data_8Y1X
# 
_entry.id   8Y1X 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8Y1X         pdb_00008y1x 10.2210/pdb8y1x/pdb 
WWPDB D_1300044662 ?            ?                   
EMDB  EMD-38849    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-29 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8Y1X 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of the aspartate:alanine antiporter AspT WT' 
_pdbx_database_related.db_id          EMD-38849 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              koshiba@megabank.tohoku.ac.jp 
_pdbx_contact_author.name_first         Seizo 
_pdbx_contact_author.name_last          Koshiba 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2001-1949 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Nanatani, K.'  1  ? 
'Kanno, R.'     2  ? 
'Kawabata, T.'  3  ? 
'Watanabe, S.'  4  ? 
'Hidaka, M.'    5  ? 
'Yamanaka, T.'  6  ? 
'Toda, K.'      7  ? 
'Fujiki, T.'    8  ? 
'Kunii, K.'     9  ? 
'Miyamoto, A.'  10 ? 
'Chiba, F.'     11 ? 
'Ogasawara, S.' 12 ? 
'Murata, T.'    13 ? 
'Humbel, B.M.'  14 ? 
'Inaba, K.'     15 ? 
'Mitsuoka, K.'  16 ? 
'Guan, L.'      17 ? 
'Abe, K.'       18 ? 
'Yamamoto, M.'  19 ? 
'Koshiba, S.'   20 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Cryo-EM structure and molecular mechanism of the aspartate:alanine antiporter AspT from Tetragenococcus halophilus' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Nanatani, K.'  1  ? 
primary 'Kanno, R.'     2  ? 
primary 'Kawabata, T.'  3  ? 
primary 'Watanabe, S.'  4  ? 
primary 'Hidaka, M.'    5  ? 
primary 'Yamanaka, T.'  6  ? 
primary 'Toda, K.'      7  ? 
primary 'Fujiki, T.'    8  ? 
primary 'Kunii, K.'     9  ? 
primary 'Miyamoto, A.'  10 ? 
primary 'Chiba, F.'     11 ? 
primary 'Ogasawara, S.' 12 ? 
primary 'Murata, T.'    13 ? 
primary 'Humbel, B.M.'  14 ? 
primary 'Inaba, K.'     15 ? 
primary 'Mitsuoka, K.'  16 ? 
primary 'Guan, L.'      17 ? 
primary 'Abe, K.'       18 ? 
primary 'Yamamoto, M.'  19 ? 
primary 'Koshiba, S.'   20 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Aspartate/alanine antiporter' 57255.129 2 ? ? ? ? 
2 non-polymer syn 'ASPARTIC ACID'                133.103   2 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MNAIGNFLVGTPVFTIFICLALGYLLGKLKIGSFTLGATVGVLIVALLIGQLGVFPRDTLLGDIFFDFFMFAIGYRVGPS
FISSMKKFGAKIVYATLIFLVSAFIVAYACFKMFHIGPGIAAGIIAGGLTQSAVIGSSLETISKLPISDHLKTLYSNQIP
IVYTLTYVFGTIGVLIFLRDIMPKLMHIDLKKQAVKTAKELDMIPVPVIVASTHFYTINDGSSLIGQTLGTVNTKFAKGL
VAAGLNDSADMASVINAGDVLAISGGIDEIGRAVQEFNLLEVTGKTKAYVSKQVVLKKNFSADVLKNAQDKGVLVATLAG
DVMDPAQFSTLKPAESVTLVGQKDAVSEVQSQLGRLRAAENIINYSWFALGIALSAALGIVGTKVSGVPIALGGGTASLI
VGLVQSIYRDKHAHMDTIPDSLLEFFQSIGLNLFIATVGLSAAKTFISAIQSMGISVLLIGAVISILPHIITFVICYYLM
KMEPISIIGAQTGADTLSAALNDVSERVGSDASPFFAAAVAPAYAIGNIFLTLMGPIFIVLLS
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MNAIGNFLVGTPVFTIFICLALGYLLGKLKIGSFTLGATVGVLIVALLIGQLGVFPRDTLLGDIFFDFFMFAIGYRVGPS
FISSMKKFGAKIVYATLIFLVSAFIVAYACFKMFHIGPGIAAGIIAGGLTQSAVIGSSLETISKLPISDHLKTLYSNQIP
IVYTLTYVFGTIGVLIFLRDIMPKLMHIDLKKQAVKTAKELDMIPVPVIVASTHFYTINDGSSLIGQTLGTVNTKFAKGL
VAAGLNDSADMASVINAGDVLAISGGIDEIGRAVQEFNLLEVTGKTKAYVSKQVVLKKNFSADVLKNAQDKGVLVATLAG
DVMDPAQFSTLKPAESVTLVGQKDAVSEVQSQLGRLRAAENIINYSWFALGIALSAALGIVGTKVSGVPIALGGGTASLI
VGLVQSIYRDKHAHMDTIPDSLLEFFQSIGLNLFIATVGLSAAKTFISAIQSMGISVLLIGAVISILPHIITFVICYYLM
KMEPISIIGAQTGADTLSAALNDVSERVGSDASPFFAAAVAPAYAIGNIFLTLMGPIFIVLLS
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'ASPARTIC ACID' 
_pdbx_entity_nonpoly.comp_id     ASP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASN n 
1 3   ALA n 
1 4   ILE n 
1 5   GLY n 
1 6   ASN n 
1 7   PHE n 
1 8   LEU n 
1 9   VAL n 
1 10  GLY n 
1 11  THR n 
1 12  PRO n 
1 13  VAL n 
1 14  PHE n 
1 15  THR n 
1 16  ILE n 
1 17  PHE n 
1 18  ILE n 
1 19  CYS n 
1 20  LEU n 
1 21  ALA n 
1 22  LEU n 
1 23  GLY n 
1 24  TYR n 
1 25  LEU n 
1 26  LEU n 
1 27  GLY n 
1 28  LYS n 
1 29  LEU n 
1 30  LYS n 
1 31  ILE n 
1 32  GLY n 
1 33  SER n 
1 34  PHE n 
1 35  THR n 
1 36  LEU n 
1 37  GLY n 
1 38  ALA n 
1 39  THR n 
1 40  VAL n 
1 41  GLY n 
1 42  VAL n 
1 43  LEU n 
1 44  ILE n 
1 45  VAL n 
1 46  ALA n 
1 47  LEU n 
1 48  LEU n 
1 49  ILE n 
1 50  GLY n 
1 51  GLN n 
1 52  LEU n 
1 53  GLY n 
1 54  VAL n 
1 55  PHE n 
1 56  PRO n 
1 57  ARG n 
1 58  ASP n 
1 59  THR n 
1 60  LEU n 
1 61  LEU n 
1 62  GLY n 
1 63  ASP n 
1 64  ILE n 
1 65  PHE n 
1 66  PHE n 
1 67  ASP n 
1 68  PHE n 
1 69  PHE n 
1 70  MET n 
1 71  PHE n 
1 72  ALA n 
1 73  ILE n 
1 74  GLY n 
1 75  TYR n 
1 76  ARG n 
1 77  VAL n 
1 78  GLY n 
1 79  PRO n 
1 80  SER n 
1 81  PHE n 
1 82  ILE n 
1 83  SER n 
1 84  SER n 
1 85  MET n 
1 86  LYS n 
1 87  LYS n 
1 88  PHE n 
1 89  GLY n 
1 90  ALA n 
1 91  LYS n 
1 92  ILE n 
1 93  VAL n 
1 94  TYR n 
1 95  ALA n 
1 96  THR n 
1 97  LEU n 
1 98  ILE n 
1 99  PHE n 
1 100 LEU n 
1 101 VAL n 
1 102 SER n 
1 103 ALA n 
1 104 PHE n 
1 105 ILE n 
1 106 VAL n 
1 107 ALA n 
1 108 TYR n 
1 109 ALA n 
1 110 CYS n 
1 111 PHE n 
1 112 LYS n 
1 113 MET n 
1 114 PHE n 
1 115 HIS n 
1 116 ILE n 
1 117 GLY n 
1 118 PRO n 
1 119 GLY n 
1 120 ILE n 
1 121 ALA n 
1 122 ALA n 
1 123 GLY n 
1 124 ILE n 
1 125 ILE n 
1 126 ALA n 
1 127 GLY n 
1 128 GLY n 
1 129 LEU n 
1 130 THR n 
1 131 GLN n 
1 132 SER n 
1 133 ALA n 
1 134 VAL n 
1 135 ILE n 
1 136 GLY n 
1 137 SER n 
1 138 SER n 
1 139 LEU n 
1 140 GLU n 
1 141 THR n 
1 142 ILE n 
1 143 SER n 
1 144 LYS n 
1 145 LEU n 
1 146 PRO n 
1 147 ILE n 
1 148 SER n 
1 149 ASP n 
1 150 HIS n 
1 151 LEU n 
1 152 LYS n 
1 153 THR n 
1 154 LEU n 
1 155 TYR n 
1 156 SER n 
1 157 ASN n 
1 158 GLN n 
1 159 ILE n 
1 160 PRO n 
1 161 ILE n 
1 162 VAL n 
1 163 TYR n 
1 164 THR n 
1 165 LEU n 
1 166 THR n 
1 167 TYR n 
1 168 VAL n 
1 169 PHE n 
1 170 GLY n 
1 171 THR n 
1 172 ILE n 
1 173 GLY n 
1 174 VAL n 
1 175 LEU n 
1 176 ILE n 
1 177 PHE n 
1 178 LEU n 
1 179 ARG n 
1 180 ASP n 
1 181 ILE n 
1 182 MET n 
1 183 PRO n 
1 184 LYS n 
1 185 LEU n 
1 186 MET n 
1 187 HIS n 
1 188 ILE n 
1 189 ASP n 
1 190 LEU n 
1 191 LYS n 
1 192 LYS n 
1 193 GLN n 
1 194 ALA n 
1 195 VAL n 
1 196 LYS n 
1 197 THR n 
1 198 ALA n 
1 199 LYS n 
1 200 GLU n 
1 201 LEU n 
1 202 ASP n 
1 203 MET n 
1 204 ILE n 
1 205 PRO n 
1 206 VAL n 
1 207 PRO n 
1 208 VAL n 
1 209 ILE n 
1 210 VAL n 
1 211 ALA n 
1 212 SER n 
1 213 THR n 
1 214 HIS n 
1 215 PHE n 
1 216 TYR n 
1 217 THR n 
1 218 ILE n 
1 219 ASN n 
1 220 ASP n 
1 221 GLY n 
1 222 SER n 
1 223 SER n 
1 224 LEU n 
1 225 ILE n 
1 226 GLY n 
1 227 GLN n 
1 228 THR n 
1 229 LEU n 
1 230 GLY n 
1 231 THR n 
1 232 VAL n 
1 233 ASN n 
1 234 THR n 
1 235 LYS n 
1 236 PHE n 
1 237 ALA n 
1 238 LYS n 
1 239 GLY n 
1 240 LEU n 
1 241 VAL n 
1 242 ALA n 
1 243 ALA n 
1 244 GLY n 
1 245 LEU n 
1 246 ASN n 
1 247 ASP n 
1 248 SER n 
1 249 ALA n 
1 250 ASP n 
1 251 MET n 
1 252 ALA n 
1 253 SER n 
1 254 VAL n 
1 255 ILE n 
1 256 ASN n 
1 257 ALA n 
1 258 GLY n 
1 259 ASP n 
1 260 VAL n 
1 261 LEU n 
1 262 ALA n 
1 263 ILE n 
1 264 SER n 
1 265 GLY n 
1 266 GLY n 
1 267 ILE n 
1 268 ASP n 
1 269 GLU n 
1 270 ILE n 
1 271 GLY n 
1 272 ARG n 
1 273 ALA n 
1 274 VAL n 
1 275 GLN n 
1 276 GLU n 
1 277 PHE n 
1 278 ASN n 
1 279 LEU n 
1 280 LEU n 
1 281 GLU n 
1 282 VAL n 
1 283 THR n 
1 284 GLY n 
1 285 LYS n 
1 286 THR n 
1 287 LYS n 
1 288 ALA n 
1 289 TYR n 
1 290 VAL n 
1 291 SER n 
1 292 LYS n 
1 293 GLN n 
1 294 VAL n 
1 295 VAL n 
1 296 LEU n 
1 297 LYS n 
1 298 LYS n 
1 299 ASN n 
1 300 PHE n 
1 301 SER n 
1 302 ALA n 
1 303 ASP n 
1 304 VAL n 
1 305 LEU n 
1 306 LYS n 
1 307 ASN n 
1 308 ALA n 
1 309 GLN n 
1 310 ASP n 
1 311 LYS n 
1 312 GLY n 
1 313 VAL n 
1 314 LEU n 
1 315 VAL n 
1 316 ALA n 
1 317 THR n 
1 318 LEU n 
1 319 ALA n 
1 320 GLY n 
1 321 ASP n 
1 322 VAL n 
1 323 MET n 
1 324 ASP n 
1 325 PRO n 
1 326 ALA n 
1 327 GLN n 
1 328 PHE n 
1 329 SER n 
1 330 THR n 
1 331 LEU n 
1 332 LYS n 
1 333 PRO n 
1 334 ALA n 
1 335 GLU n 
1 336 SER n 
1 337 VAL n 
1 338 THR n 
1 339 LEU n 
1 340 VAL n 
1 341 GLY n 
1 342 GLN n 
1 343 LYS n 
1 344 ASP n 
1 345 ALA n 
1 346 VAL n 
1 347 SER n 
1 348 GLU n 
1 349 VAL n 
1 350 GLN n 
1 351 SER n 
1 352 GLN n 
1 353 LEU n 
1 354 GLY n 
1 355 ARG n 
1 356 LEU n 
1 357 ARG n 
1 358 ALA n 
1 359 ALA n 
1 360 GLU n 
1 361 ASN n 
1 362 ILE n 
1 363 ILE n 
1 364 ASN n 
1 365 TYR n 
1 366 SER n 
1 367 TRP n 
1 368 PHE n 
1 369 ALA n 
1 370 LEU n 
1 371 GLY n 
1 372 ILE n 
1 373 ALA n 
1 374 LEU n 
1 375 SER n 
1 376 ALA n 
1 377 ALA n 
1 378 LEU n 
1 379 GLY n 
1 380 ILE n 
1 381 VAL n 
1 382 GLY n 
1 383 THR n 
1 384 LYS n 
1 385 VAL n 
1 386 SER n 
1 387 GLY n 
1 388 VAL n 
1 389 PRO n 
1 390 ILE n 
1 391 ALA n 
1 392 LEU n 
1 393 GLY n 
1 394 GLY n 
1 395 GLY n 
1 396 THR n 
1 397 ALA n 
1 398 SER n 
1 399 LEU n 
1 400 ILE n 
1 401 VAL n 
1 402 GLY n 
1 403 LEU n 
1 404 VAL n 
1 405 GLN n 
1 406 SER n 
1 407 ILE n 
1 408 TYR n 
1 409 ARG n 
1 410 ASP n 
1 411 LYS n 
1 412 HIS n 
1 413 ALA n 
1 414 HIS n 
1 415 MET n 
1 416 ASP n 
1 417 THR n 
1 418 ILE n 
1 419 PRO n 
1 420 ASP n 
1 421 SER n 
1 422 LEU n 
1 423 LEU n 
1 424 GLU n 
1 425 PHE n 
1 426 PHE n 
1 427 GLN n 
1 428 SER n 
1 429 ILE n 
1 430 GLY n 
1 431 LEU n 
1 432 ASN n 
1 433 LEU n 
1 434 PHE n 
1 435 ILE n 
1 436 ALA n 
1 437 THR n 
1 438 VAL n 
1 439 GLY n 
1 440 LEU n 
1 441 SER n 
1 442 ALA n 
1 443 ALA n 
1 444 LYS n 
1 445 THR n 
1 446 PHE n 
1 447 ILE n 
1 448 SER n 
1 449 ALA n 
1 450 ILE n 
1 451 GLN n 
1 452 SER n 
1 453 MET n 
1 454 GLY n 
1 455 ILE n 
1 456 SER n 
1 457 VAL n 
1 458 LEU n 
1 459 LEU n 
1 460 ILE n 
1 461 GLY n 
1 462 ALA n 
1 463 VAL n 
1 464 ILE n 
1 465 SER n 
1 466 ILE n 
1 467 LEU n 
1 468 PRO n 
1 469 HIS n 
1 470 ILE n 
1 471 ILE n 
1 472 THR n 
1 473 PHE n 
1 474 VAL n 
1 475 ILE n 
1 476 CYS n 
1 477 TYR n 
1 478 TYR n 
1 479 LEU n 
1 480 MET n 
1 481 LYS n 
1 482 MET n 
1 483 GLU n 
1 484 PRO n 
1 485 ILE n 
1 486 SER n 
1 487 ILE n 
1 488 ILE n 
1 489 GLY n 
1 490 ALA n 
1 491 GLN n 
1 492 THR n 
1 493 GLY n 
1 494 ALA n 
1 495 ASP n 
1 496 THR n 
1 497 LEU n 
1 498 SER n 
1 499 ALA n 
1 500 ALA n 
1 501 LEU n 
1 502 ASN n 
1 503 ASP n 
1 504 VAL n 
1 505 SER n 
1 506 GLU n 
1 507 ARG n 
1 508 VAL n 
1 509 GLY n 
1 510 SER n 
1 511 ASP n 
1 512 ALA n 
1 513 SER n 
1 514 PRO n 
1 515 PHE n 
1 516 PHE n 
1 517 ALA n 
1 518 ALA n 
1 519 ALA n 
1 520 VAL n 
1 521 ALA n 
1 522 PRO n 
1 523 ALA n 
1 524 TYR n 
1 525 ALA n 
1 526 ILE n 
1 527 GLY n 
1 528 ASN n 
1 529 ILE n 
1 530 PHE n 
1 531 LEU n 
1 532 THR n 
1 533 LEU n 
1 534 MET n 
1 535 GLY n 
1 536 PRO n 
1 537 ILE n 
1 538 PHE n 
1 539 ILE n 
1 540 VAL n 
1 541 LEU n 
1 542 LEU n 
1 543 SER n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   543 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 aspT 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    D10 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Tetragenococcus halophilus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     51669 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              C43 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pTrc99a 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   ASN 2   2   2   ASN ASN A . n 
A 1 3   ALA 3   3   3   ALA ALA A . n 
A 1 4   ILE 4   4   4   ILE ILE A . n 
A 1 5   GLY 5   5   5   GLY GLY A . n 
A 1 6   ASN 6   6   6   ASN ASN A . n 
A 1 7   PHE 7   7   7   PHE PHE A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   VAL 9   9   9   VAL VAL A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  THR 11  11  11  THR THR A . n 
A 1 12  PRO 12  12  12  PRO PRO A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  PHE 14  14  14  PHE PHE A . n 
A 1 15  THR 15  15  15  THR THR A . n 
A 1 16  ILE 16  16  16  ILE ILE A . n 
A 1 17  PHE 17  17  17  PHE PHE A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  CYS 19  19  19  CYS ALA A . n 
A 1 20  LEU 20  20  20  LEU LEU A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  LEU 22  22  22  LEU LEU A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  TYR 24  24  24  TYR TYR A . n 
A 1 25  LEU 25  25  25  LEU LEU A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  GLY 27  27  27  GLY GLY A . n 
A 1 28  LYS 28  28  28  LYS LYS A . n 
A 1 29  LEU 29  29  29  LEU LEU A . n 
A 1 30  LYS 30  30  30  LYS LYS A . n 
A 1 31  ILE 31  31  31  ILE ILE A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  SER 33  33  33  SER SER A . n 
A 1 34  PHE 34  34  34  PHE PHE A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  GLY 37  37  37  GLY GLY A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  THR 39  39  39  THR THR A . n 
A 1 40  VAL 40  40  40  VAL VAL A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  ILE 44  44  44  ILE ILE A . n 
A 1 45  VAL 45  45  45  VAL VAL A . n 
A 1 46  ALA 46  46  46  ALA ALA A . n 
A 1 47  LEU 47  47  47  LEU LEU A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  GLY 50  50  50  GLY GLY A . n 
A 1 51  GLN 51  51  51  GLN GLN A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  VAL 54  54  54  VAL VAL A . n 
A 1 55  PHE 55  55  55  PHE PHE A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  LEU 60  60  60  LEU LEU A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  PHE 65  65  65  PHE PHE A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  ASP 67  67  67  ASP ASP A . n 
A 1 68  PHE 68  68  68  PHE PHE A . n 
A 1 69  PHE 69  69  69  PHE PHE A . n 
A 1 70  MET 70  70  70  MET MET A . n 
A 1 71  PHE 71  71  71  PHE PHE A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  SER 80  80  80  SER SER A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  ILE 82  82  82  ILE ILE A . n 
A 1 83  SER 83  83  83  SER SER A . n 
A 1 84  SER 84  84  84  SER SER A . n 
A 1 85  MET 85  85  85  MET MET A . n 
A 1 86  LYS 86  86  86  LYS LYS A . n 
A 1 87  LYS 87  87  87  LYS LYS A . n 
A 1 88  PHE 88  88  88  PHE PHE A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  LYS 91  91  91  LYS LYS A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  VAL 93  93  93  VAL VAL A . n 
A 1 94  TYR 94  94  94  TYR TYR A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  THR 96  96  96  THR THR A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  ILE 98  98  98  ILE ILE A . n 
A 1 99  PHE 99  99  99  PHE PHE A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 VAL 101 101 101 VAL VAL A . n 
A 1 102 SER 102 102 102 SER SER A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 PHE 104 104 104 PHE PHE A . n 
A 1 105 ILE 105 105 105 ILE ILE A . n 
A 1 106 VAL 106 106 106 VAL VAL A . n 
A 1 107 ALA 107 107 107 ALA ALA A . n 
A 1 108 TYR 108 108 108 TYR TYR A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 CYS 110 110 110 CYS ALA A . n 
A 1 111 PHE 111 111 111 PHE PHE A . n 
A 1 112 LYS 112 112 112 LYS LYS A . n 
A 1 113 MET 113 113 113 MET MET A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 HIS 115 115 115 HIS HIS A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 PRO 118 118 118 PRO PRO A . n 
A 1 119 GLY 119 119 119 GLY GLY A . n 
A 1 120 ILE 120 120 120 ILE ILE A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 ALA 122 122 122 ALA ALA A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 ILE 125 125 125 ILE ILE A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 GLN 131 131 131 GLN GLN A . n 
A 1 132 SER 132 132 132 SER SER A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 ILE 135 135 135 ILE ILE A . n 
A 1 136 GLY 136 136 136 GLY GLY A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 LEU 139 139 139 LEU LEU A . n 
A 1 140 GLU 140 140 140 GLU GLU A . n 
A 1 141 THR 141 141 141 THR THR A . n 
A 1 142 ILE 142 142 142 ILE ILE A . n 
A 1 143 SER 143 143 143 SER SER A . n 
A 1 144 LYS 144 144 144 LYS LYS A . n 
A 1 145 LEU 145 145 145 LEU LEU A . n 
A 1 146 PRO 146 146 146 PRO PRO A . n 
A 1 147 ILE 147 147 147 ILE ILE A . n 
A 1 148 SER 148 148 148 SER SER A . n 
A 1 149 ASP 149 149 149 ASP ASP A . n 
A 1 150 HIS 150 150 150 HIS HIS A . n 
A 1 151 LEU 151 151 151 LEU LEU A . n 
A 1 152 LYS 152 152 152 LYS LYS A . n 
A 1 153 THR 153 153 153 THR THR A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 SER 156 156 156 SER SER A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 GLN 158 158 158 GLN GLN A . n 
A 1 159 ILE 159 159 159 ILE ILE A . n 
A 1 160 PRO 160 160 160 PRO PRO A . n 
A 1 161 ILE 161 161 161 ILE ILE A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 TYR 163 163 163 TYR TYR A . n 
A 1 164 THR 164 164 164 THR THR A . n 
A 1 165 LEU 165 165 165 LEU LEU A . n 
A 1 166 THR 166 166 166 THR THR A . n 
A 1 167 TYR 167 167 167 TYR TYR A . n 
A 1 168 VAL 168 168 168 VAL VAL A . n 
A 1 169 PHE 169 169 169 PHE PHE A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 THR 171 171 171 THR THR A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 GLY 173 173 173 GLY GLY A . n 
A 1 174 VAL 174 174 174 VAL VAL A . n 
A 1 175 LEU 175 175 175 LEU LEU A . n 
A 1 176 ILE 176 176 176 ILE ILE A . n 
A 1 177 PHE 177 177 177 PHE PHE A . n 
A 1 178 LEU 178 178 178 LEU LEU A . n 
A 1 179 ARG 179 179 179 ARG ARG A . n 
A 1 180 ASP 180 180 180 ASP ASP A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 MET 182 182 182 MET MET A . n 
A 1 183 PRO 183 183 183 PRO PRO A . n 
A 1 184 LYS 184 184 184 LYS LYS A . n 
A 1 185 LEU 185 185 185 LEU LEU A . n 
A 1 186 MET 186 186 186 MET MET A . n 
A 1 187 HIS 187 187 187 HIS HIS A . n 
A 1 188 ILE 188 188 188 ILE ILE A . n 
A 1 189 ASP 189 189 189 ASP ASP A . n 
A 1 190 LEU 190 190 190 LEU LEU A . n 
A 1 191 LYS 191 191 191 LYS LYS A . n 
A 1 192 LYS 192 192 192 LYS LYS A . n 
A 1 193 GLN 193 193 193 GLN GLN A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 THR 197 197 197 THR THR A . n 
A 1 198 ALA 198 198 198 ALA ALA A . n 
A 1 199 LYS 199 199 199 LYS LYS A . n 
A 1 200 GLU 200 200 200 GLU GLU A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 ASP 202 202 202 ASP ASP A . n 
A 1 203 MET 203 203 203 MET MET A . n 
A 1 204 ILE 204 204 204 ILE ILE A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 VAL 206 206 206 VAL VAL A . n 
A 1 207 PRO 207 207 207 PRO PRO A . n 
A 1 208 VAL 208 208 208 VAL VAL A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 VAL 210 210 210 VAL VAL A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 SER 212 212 212 SER SER A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 HIS 214 214 214 HIS HIS A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 TYR 216 216 216 TYR TYR A . n 
A 1 217 THR 217 217 217 THR THR A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 ASN 219 219 219 ASN ASN A . n 
A 1 220 ASP 220 220 220 ASP ASP A . n 
A 1 221 GLY 221 221 221 GLY GLY A . n 
A 1 222 SER 222 222 222 SER SER A . n 
A 1 223 SER 223 223 223 SER SER A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 ILE 225 225 225 ILE ILE A . n 
A 1 226 GLY 226 226 226 GLY GLY A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 THR 228 228 228 THR THR A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 THR 231 231 231 THR THR A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 ASN 233 233 233 ASN ASN A . n 
A 1 234 THR 234 234 234 THR THR A . n 
A 1 235 LYS 235 235 235 LYS LYS A . n 
A 1 236 PHE 236 236 236 PHE PHE A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 LYS 238 238 238 LYS LYS A . n 
A 1 239 GLY 239 239 239 GLY GLY A . n 
A 1 240 LEU 240 240 240 LEU LEU A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 ALA 242 242 242 ALA ALA A . n 
A 1 243 ALA 243 243 243 ALA ALA A . n 
A 1 244 GLY 244 244 244 GLY GLY A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 ASN 246 246 246 ASN ASN A . n 
A 1 247 ASP 247 247 247 ASP ASP A . n 
A 1 248 SER 248 248 248 SER SER A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 ASP 250 250 250 ASP ASP A . n 
A 1 251 MET 251 251 251 MET MET A . n 
A 1 252 ALA 252 252 252 ALA ALA A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 ILE 255 255 255 ILE ILE A . n 
A 1 256 ASN 256 256 256 ASN ASN A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 ASP 259 259 259 ASP ASP A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 ALA 262 262 262 ALA ALA A . n 
A 1 263 ILE 263 263 263 ILE ILE A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 GLY 266 266 266 GLY GLY A . n 
A 1 267 ILE 267 267 267 ILE ILE A . n 
A 1 268 ASP 268 268 268 ASP ASP A . n 
A 1 269 GLU 269 269 269 GLU GLU A . n 
A 1 270 ILE 270 270 270 ILE ILE A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 ARG 272 272 272 ARG ARG A . n 
A 1 273 ALA 273 273 273 ALA ALA A . n 
A 1 274 VAL 274 274 274 VAL VAL A . n 
A 1 275 GLN 275 275 275 GLN GLN A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 PHE 277 277 277 PHE PHE A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 VAL 282 282 282 VAL VAL A . n 
A 1 283 THR 283 283 283 THR THR A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 LYS 285 285 285 LYS LYS A . n 
A 1 286 THR 286 286 286 THR THR A . n 
A 1 287 LYS 287 287 287 LYS LYS A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 TYR 289 289 289 TYR TYR A . n 
A 1 290 VAL 290 290 290 VAL VAL A . n 
A 1 291 SER 291 291 291 SER SER A . n 
A 1 292 LYS 292 292 292 LYS LYS A . n 
A 1 293 GLN 293 293 293 GLN GLN A . n 
A 1 294 VAL 294 294 294 VAL VAL A . n 
A 1 295 VAL 295 295 295 VAL VAL A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 LYS 297 297 297 LYS LYS A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 ASN 299 299 299 ASN ASN A . n 
A 1 300 PHE 300 300 300 PHE PHE A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 ALA 302 302 302 ALA ALA A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 LYS 306 306 306 LYS LYS A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 ALA 308 308 308 ALA ALA A . n 
A 1 309 GLN 309 309 309 GLN GLN A . n 
A 1 310 ASP 310 310 310 ASP ASP A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 LEU 314 314 314 LEU LEU A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 ALA 316 316 316 ALA ALA A . n 
A 1 317 THR 317 317 317 THR THR A . n 
A 1 318 LEU 318 318 318 LEU LEU A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 GLY 320 320 320 GLY GLY A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 MET 323 323 323 MET MET A . n 
A 1 324 ASP 324 324 324 ASP ASP A . n 
A 1 325 PRO 325 325 325 PRO PRO A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 GLN 327 327 327 GLN GLN A . n 
A 1 328 PHE 328 328 328 PHE PHE A . n 
A 1 329 SER 329 329 329 SER SER A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 LYS 332 332 332 LYS LYS A . n 
A 1 333 PRO 333 333 333 PRO PRO A . n 
A 1 334 ALA 334 334 334 ALA ALA A . n 
A 1 335 GLU 335 335 335 GLU GLU A . n 
A 1 336 SER 336 336 336 SER SER A . n 
A 1 337 VAL 337 337 337 VAL VAL A . n 
A 1 338 THR 338 338 338 THR THR A . n 
A 1 339 LEU 339 339 339 LEU LEU A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 GLY 341 341 341 GLY GLY A . n 
A 1 342 GLN 342 342 342 GLN GLN A . n 
A 1 343 LYS 343 343 343 LYS LYS A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 ALA 345 345 345 ALA ALA A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 GLU 348 348 348 GLU GLU A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 GLN 350 350 350 GLN GLN A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 GLN 352 352 352 GLN GLN A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 ARG 355 355 355 ARG ARG A . n 
A 1 356 LEU 356 356 356 LEU LEU A . n 
A 1 357 ARG 357 357 357 ARG ARG A . n 
A 1 358 ALA 358 358 358 ALA ALA A . n 
A 1 359 ALA 359 359 359 ALA ALA A . n 
A 1 360 GLU 360 360 360 GLU GLU A . n 
A 1 361 ASN 361 361 361 ASN ASN A . n 
A 1 362 ILE 362 362 362 ILE ILE A . n 
A 1 363 ILE 363 363 363 ILE ILE A . n 
A 1 364 ASN 364 364 364 ASN ASN A . n 
A 1 365 TYR 365 365 365 TYR TYR A . n 
A 1 366 SER 366 366 366 SER SER A . n 
A 1 367 TRP 367 367 367 TRP TRP A . n 
A 1 368 PHE 368 368 368 PHE PHE A . n 
A 1 369 ALA 369 369 369 ALA ALA A . n 
A 1 370 LEU 370 370 370 LEU LEU A . n 
A 1 371 GLY 371 371 371 GLY GLY A . n 
A 1 372 ILE 372 372 372 ILE ILE A . n 
A 1 373 ALA 373 373 373 ALA ALA A . n 
A 1 374 LEU 374 374 374 LEU LEU A . n 
A 1 375 SER 375 375 375 SER SER A . n 
A 1 376 ALA 376 376 376 ALA ALA A . n 
A 1 377 ALA 377 377 377 ALA ALA A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 GLY 379 379 379 GLY GLY A . n 
A 1 380 ILE 380 380 380 ILE ILE A . n 
A 1 381 VAL 381 381 381 VAL VAL A . n 
A 1 382 GLY 382 382 382 GLY GLY A . n 
A 1 383 THR 383 383 383 THR THR A . n 
A 1 384 LYS 384 384 384 LYS LYS A . n 
A 1 385 VAL 385 385 385 VAL VAL A . n 
A 1 386 SER 386 386 386 SER SER A . n 
A 1 387 GLY 387 387 387 GLY GLY A . n 
A 1 388 VAL 388 388 388 VAL VAL A . n 
A 1 389 PRO 389 389 389 PRO PRO A . n 
A 1 390 ILE 390 390 390 ILE ILE A . n 
A 1 391 ALA 391 391 391 ALA ALA A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 GLY 393 393 393 GLY GLY A . n 
A 1 394 GLY 394 394 394 GLY GLY A . n 
A 1 395 GLY 395 395 395 GLY GLY A . n 
A 1 396 THR 396 396 396 THR THR A . n 
A 1 397 ALA 397 397 397 ALA ALA A . n 
A 1 398 SER 398 398 398 SER SER A . n 
A 1 399 LEU 399 399 399 LEU LEU A . n 
A 1 400 ILE 400 400 400 ILE ILE A . n 
A 1 401 VAL 401 401 401 VAL VAL A . n 
A 1 402 GLY 402 402 402 GLY GLY A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 VAL 404 404 404 VAL VAL A . n 
A 1 405 GLN 405 405 405 GLN GLN A . n 
A 1 406 SER 406 406 406 SER SER A . n 
A 1 407 ILE 407 407 407 ILE ILE A . n 
A 1 408 TYR 408 408 408 TYR TYR A . n 
A 1 409 ARG 409 409 409 ARG ARG A . n 
A 1 410 ASP 410 410 410 ASP ASP A . n 
A 1 411 LYS 411 411 411 LYS LYS A . n 
A 1 412 HIS 412 412 412 HIS HIS A . n 
A 1 413 ALA 413 413 413 ALA ALA A . n 
A 1 414 HIS 414 414 414 HIS HIS A . n 
A 1 415 MET 415 415 415 MET MET A . n 
A 1 416 ASP 416 416 416 ASP ASP A . n 
A 1 417 THR 417 417 417 THR THR A . n 
A 1 418 ILE 418 418 418 ILE ILE A . n 
A 1 419 PRO 419 419 419 PRO PRO A . n 
A 1 420 ASP 420 420 420 ASP ASP A . n 
A 1 421 SER 421 421 421 SER SER A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 LEU 423 423 423 LEU LEU A . n 
A 1 424 GLU 424 424 424 GLU GLU A . n 
A 1 425 PHE 425 425 425 PHE PHE A . n 
A 1 426 PHE 426 426 426 PHE PHE A . n 
A 1 427 GLN 427 427 427 GLN GLN A . n 
A 1 428 SER 428 428 428 SER SER A . n 
A 1 429 ILE 429 429 429 ILE ILE A . n 
A 1 430 GLY 430 430 430 GLY GLY A . n 
A 1 431 LEU 431 431 431 LEU LEU A . n 
A 1 432 ASN 432 432 432 ASN ASN A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 PHE 434 434 434 PHE PHE A . n 
A 1 435 ILE 435 435 435 ILE ILE A . n 
A 1 436 ALA 436 436 436 ALA ALA A . n 
A 1 437 THR 437 437 437 THR THR A . n 
A 1 438 VAL 438 438 438 VAL VAL A . n 
A 1 439 GLY 439 439 439 GLY GLY A . n 
A 1 440 LEU 440 440 440 LEU LEU A . n 
A 1 441 SER 441 441 441 SER SER A . n 
A 1 442 ALA 442 442 442 ALA ALA A . n 
A 1 443 ALA 443 443 443 ALA ALA A . n 
A 1 444 LYS 444 444 444 LYS LYS A . n 
A 1 445 THR 445 445 445 THR THR A . n 
A 1 446 PHE 446 446 446 PHE PHE A . n 
A 1 447 ILE 447 447 447 ILE ILE A . n 
A 1 448 SER 448 448 448 SER SER A . n 
A 1 449 ALA 449 449 449 ALA ALA A . n 
A 1 450 ILE 450 450 450 ILE ILE A . n 
A 1 451 GLN 451 451 451 GLN GLN A . n 
A 1 452 SER 452 452 452 SER SER A . n 
A 1 453 MET 453 453 453 MET MET A . n 
A 1 454 GLY 454 454 454 GLY GLY A . n 
A 1 455 ILE 455 455 455 ILE ILE A . n 
A 1 456 SER 456 456 456 SER SER A . n 
A 1 457 VAL 457 457 457 VAL VAL A . n 
A 1 458 LEU 458 458 458 LEU LEU A . n 
A 1 459 LEU 459 459 459 LEU LEU A . n 
A 1 460 ILE 460 460 460 ILE ILE A . n 
A 1 461 GLY 461 461 461 GLY GLY A . n 
A 1 462 ALA 462 462 462 ALA ALA A . n 
A 1 463 VAL 463 463 463 VAL VAL A . n 
A 1 464 ILE 464 464 464 ILE ILE A . n 
A 1 465 SER 465 465 465 SER SER A . n 
A 1 466 ILE 466 466 466 ILE ILE A . n 
A 1 467 LEU 467 467 467 LEU LEU A . n 
A 1 468 PRO 468 468 468 PRO PRO A . n 
A 1 469 HIS 469 469 469 HIS HIS A . n 
A 1 470 ILE 470 470 470 ILE ILE A . n 
A 1 471 ILE 471 471 471 ILE ILE A . n 
A 1 472 THR 472 472 472 THR THR A . n 
A 1 473 PHE 473 473 473 PHE PHE A . n 
A 1 474 VAL 474 474 474 VAL VAL A . n 
A 1 475 ILE 475 475 475 ILE ILE A . n 
A 1 476 CYS 476 476 476 CYS ALA A . n 
A 1 477 TYR 477 477 477 TYR TYR A . n 
A 1 478 TYR 478 478 478 TYR TYR A . n 
A 1 479 LEU 479 479 479 LEU LEU A . n 
A 1 480 MET 480 480 480 MET MET A . n 
A 1 481 LYS 481 481 481 LYS LYS A . n 
A 1 482 MET 482 482 482 MET MET A . n 
A 1 483 GLU 483 483 483 GLU GLU A . n 
A 1 484 PRO 484 484 484 PRO PRO A . n 
A 1 485 ILE 485 485 485 ILE ILE A . n 
A 1 486 SER 486 486 486 SER SER A . n 
A 1 487 ILE 487 487 487 ILE ILE A . n 
A 1 488 ILE 488 488 488 ILE ILE A . n 
A 1 489 GLY 489 489 489 GLY GLY A . n 
A 1 490 ALA 490 490 490 ALA ALA A . n 
A 1 491 GLN 491 491 491 GLN GLN A . n 
A 1 492 THR 492 492 492 THR THR A . n 
A 1 493 GLY 493 493 493 GLY GLY A . n 
A 1 494 ALA 494 494 494 ALA ALA A . n 
A 1 495 ASP 495 495 495 ASP ASP A . n 
A 1 496 THR 496 496 496 THR THR A . n 
A 1 497 LEU 497 497 497 LEU LEU A . n 
A 1 498 SER 498 498 498 SER SER A . n 
A 1 499 ALA 499 499 499 ALA ALA A . n 
A 1 500 ALA 500 500 500 ALA ALA A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 ASN 502 502 502 ASN ASN A . n 
A 1 503 ASP 503 503 503 ASP ASP A . n 
A 1 504 VAL 504 504 504 VAL VAL A . n 
A 1 505 SER 505 505 505 SER SER A . n 
A 1 506 GLU 506 506 506 GLU GLU A . n 
A 1 507 ARG 507 507 507 ARG ARG A . n 
A 1 508 VAL 508 508 508 VAL VAL A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 SER 510 510 510 SER SER A . n 
A 1 511 ASP 511 511 511 ASP ASP A . n 
A 1 512 ALA 512 512 512 ALA ALA A . n 
A 1 513 SER 513 513 513 SER SER A . n 
A 1 514 PRO 514 514 514 PRO PRO A . n 
A 1 515 PHE 515 515 515 PHE PHE A . n 
A 1 516 PHE 516 516 516 PHE PHE A . n 
A 1 517 ALA 517 517 517 ALA ALA A . n 
A 1 518 ALA 518 518 518 ALA ALA A . n 
A 1 519 ALA 519 519 519 ALA ALA A . n 
A 1 520 VAL 520 520 520 VAL VAL A . n 
A 1 521 ALA 521 521 521 ALA ALA A . n 
A 1 522 PRO 522 522 522 PRO PRO A . n 
A 1 523 ALA 523 523 523 ALA ALA A . n 
A 1 524 TYR 524 524 524 TYR TYR A . n 
A 1 525 ALA 525 525 525 ALA ALA A . n 
A 1 526 ILE 526 526 526 ILE ILE A . n 
A 1 527 GLY 527 527 527 GLY GLY A . n 
A 1 528 ASN 528 528 528 ASN ASN A . n 
A 1 529 ILE 529 529 529 ILE ILE A . n 
A 1 530 PHE 530 530 530 PHE PHE A . n 
A 1 531 LEU 531 531 531 LEU LEU A . n 
A 1 532 THR 532 532 532 THR THR A . n 
A 1 533 LEU 533 533 533 LEU LEU A . n 
A 1 534 MET 534 534 534 MET MET A . n 
A 1 535 GLY 535 535 535 GLY GLY A . n 
A 1 536 PRO 536 536 536 PRO PRO A . n 
A 1 537 ILE 537 537 537 ILE ILE A . n 
A 1 538 PHE 538 538 538 PHE PHE A . n 
A 1 539 ILE 539 539 539 ILE ILE A . n 
A 1 540 VAL 540 540 540 VAL VAL A . n 
A 1 541 LEU 541 541 541 LEU LEU A . n 
A 1 542 LEU 542 542 542 LEU LEU A . n 
A 1 543 SER 543 543 543 SER SER A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   ASN 2   2   2   ASN ASN B . n 
B 1 3   ALA 3   3   3   ALA ALA B . n 
B 1 4   ILE 4   4   4   ILE ILE B . n 
B 1 5   GLY 5   5   5   GLY GLY B . n 
B 1 6   ASN 6   6   6   ASN ASN B . n 
B 1 7   PHE 7   7   7   PHE PHE B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   VAL 9   9   9   VAL VAL B . n 
B 1 10  GLY 10  10  10  GLY GLY B . n 
B 1 11  THR 11  11  11  THR THR B . n 
B 1 12  PRO 12  12  12  PRO PRO B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  PHE 14  14  14  PHE PHE B . n 
B 1 15  THR 15  15  15  THR THR B . n 
B 1 16  ILE 16  16  16  ILE ILE B . n 
B 1 17  PHE 17  17  17  PHE PHE B . n 
B 1 18  ILE 18  18  18  ILE ILE B . n 
B 1 19  CYS 19  19  19  CYS ALA B . n 
B 1 20  LEU 20  20  20  LEU LEU B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  LEU 22  22  22  LEU LEU B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  TYR 24  24  24  TYR TYR B . n 
B 1 25  LEU 25  25  25  LEU LEU B . n 
B 1 26  LEU 26  26  26  LEU LEU B . n 
B 1 27  GLY 27  27  27  GLY GLY B . n 
B 1 28  LYS 28  28  28  LYS LYS B . n 
B 1 29  LEU 29  29  29  LEU LEU B . n 
B 1 30  LYS 30  30  30  LYS LYS B . n 
B 1 31  ILE 31  31  31  ILE ILE B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  SER 33  33  33  SER SER B . n 
B 1 34  PHE 34  34  34  PHE PHE B . n 
B 1 35  THR 35  35  35  THR THR B . n 
B 1 36  LEU 36  36  36  LEU LEU B . n 
B 1 37  GLY 37  37  37  GLY GLY B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  THR 39  39  39  THR THR B . n 
B 1 40  VAL 40  40  40  VAL VAL B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  LEU 43  43  43  LEU LEU B . n 
B 1 44  ILE 44  44  44  ILE ILE B . n 
B 1 45  VAL 45  45  45  VAL VAL B . n 
B 1 46  ALA 46  46  46  ALA ALA B . n 
B 1 47  LEU 47  47  47  LEU LEU B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  ILE 49  49  49  ILE ILE B . n 
B 1 50  GLY 50  50  50  GLY GLY B . n 
B 1 51  GLN 51  51  51  GLN GLN B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  GLY 53  53  53  GLY GLY B . n 
B 1 54  VAL 54  54  54  VAL VAL B . n 
B 1 55  PHE 55  55  55  PHE PHE B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  ARG 57  57  57  ARG ARG B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  THR 59  59  59  THR THR B . n 
B 1 60  LEU 60  60  60  LEU LEU B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  GLY 62  62  62  GLY GLY B . n 
B 1 63  ASP 63  63  63  ASP ASP B . n 
B 1 64  ILE 64  64  64  ILE ILE B . n 
B 1 65  PHE 65  65  65  PHE PHE B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  ASP 67  67  67  ASP ASP B . n 
B 1 68  PHE 68  68  68  PHE PHE B . n 
B 1 69  PHE 69  69  69  PHE PHE B . n 
B 1 70  MET 70  70  70  MET MET B . n 
B 1 71  PHE 71  71  71  PHE PHE B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  ILE 73  73  73  ILE ILE B . n 
B 1 74  GLY 74  74  74  GLY GLY B . n 
B 1 75  TYR 75  75  75  TYR TYR B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  GLY 78  78  78  GLY GLY B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  SER 80  80  80  SER SER B . n 
B 1 81  PHE 81  81  81  PHE PHE B . n 
B 1 82  ILE 82  82  82  ILE ILE B . n 
B 1 83  SER 83  83  83  SER SER B . n 
B 1 84  SER 84  84  84  SER SER B . n 
B 1 85  MET 85  85  85  MET MET B . n 
B 1 86  LYS 86  86  86  LYS LYS B . n 
B 1 87  LYS 87  87  87  LYS LYS B . n 
B 1 88  PHE 88  88  88  PHE PHE B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  LYS 91  91  91  LYS LYS B . n 
B 1 92  ILE 92  92  92  ILE ILE B . n 
B 1 93  VAL 93  93  93  VAL VAL B . n 
B 1 94  TYR 94  94  94  TYR TYR B . n 
B 1 95  ALA 95  95  95  ALA ALA B . n 
B 1 96  THR 96  96  96  THR THR B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  ILE 98  98  98  ILE ILE B . n 
B 1 99  PHE 99  99  99  PHE PHE B . n 
B 1 100 LEU 100 100 100 LEU LEU B . n 
B 1 101 VAL 101 101 101 VAL VAL B . n 
B 1 102 SER 102 102 102 SER SER B . n 
B 1 103 ALA 103 103 103 ALA ALA B . n 
B 1 104 PHE 104 104 104 PHE PHE B . n 
B 1 105 ILE 105 105 105 ILE ILE B . n 
B 1 106 VAL 106 106 106 VAL VAL B . n 
B 1 107 ALA 107 107 107 ALA ALA B . n 
B 1 108 TYR 108 108 108 TYR TYR B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 CYS 110 110 110 CYS ALA B . n 
B 1 111 PHE 111 111 111 PHE PHE B . n 
B 1 112 LYS 112 112 112 LYS LYS B . n 
B 1 113 MET 113 113 113 MET MET B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 HIS 115 115 115 HIS HIS B . n 
B 1 116 ILE 116 116 116 ILE ILE B . n 
B 1 117 GLY 117 117 117 GLY GLY B . n 
B 1 118 PRO 118 118 118 PRO PRO B . n 
B 1 119 GLY 119 119 119 GLY GLY B . n 
B 1 120 ILE 120 120 120 ILE ILE B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 ALA 122 122 122 ALA ALA B . n 
B 1 123 GLY 123 123 123 GLY GLY B . n 
B 1 124 ILE 124 124 124 ILE ILE B . n 
B 1 125 ILE 125 125 125 ILE ILE B . n 
B 1 126 ALA 126 126 126 ALA ALA B . n 
B 1 127 GLY 127 127 127 GLY GLY B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 THR 130 130 130 THR THR B . n 
B 1 131 GLN 131 131 131 GLN GLN B . n 
B 1 132 SER 132 132 132 SER SER B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 VAL 134 134 134 VAL VAL B . n 
B 1 135 ILE 135 135 135 ILE ILE B . n 
B 1 136 GLY 136 136 136 GLY GLY B . n 
B 1 137 SER 137 137 137 SER SER B . n 
B 1 138 SER 138 138 138 SER SER B . n 
B 1 139 LEU 139 139 139 LEU LEU B . n 
B 1 140 GLU 140 140 140 GLU GLU B . n 
B 1 141 THR 141 141 141 THR THR B . n 
B 1 142 ILE 142 142 142 ILE ILE B . n 
B 1 143 SER 143 143 143 SER SER B . n 
B 1 144 LYS 144 144 144 LYS LYS B . n 
B 1 145 LEU 145 145 145 LEU LEU B . n 
B 1 146 PRO 146 146 146 PRO PRO B . n 
B 1 147 ILE 147 147 147 ILE ILE B . n 
B 1 148 SER 148 148 148 SER SER B . n 
B 1 149 ASP 149 149 149 ASP ASP B . n 
B 1 150 HIS 150 150 150 HIS HIS B . n 
B 1 151 LEU 151 151 151 LEU LEU B . n 
B 1 152 LYS 152 152 152 LYS LYS B . n 
B 1 153 THR 153 153 153 THR THR B . n 
B 1 154 LEU 154 154 154 LEU LEU B . n 
B 1 155 TYR 155 155 155 TYR TYR B . n 
B 1 156 SER 156 156 156 SER SER B . n 
B 1 157 ASN 157 157 157 ASN ASN B . n 
B 1 158 GLN 158 158 158 GLN GLN B . n 
B 1 159 ILE 159 159 159 ILE ILE B . n 
B 1 160 PRO 160 160 160 PRO PRO B . n 
B 1 161 ILE 161 161 161 ILE ILE B . n 
B 1 162 VAL 162 162 162 VAL VAL B . n 
B 1 163 TYR 163 163 163 TYR TYR B . n 
B 1 164 THR 164 164 164 THR THR B . n 
B 1 165 LEU 165 165 165 LEU LEU B . n 
B 1 166 THR 166 166 166 THR THR B . n 
B 1 167 TYR 167 167 167 TYR TYR B . n 
B 1 168 VAL 168 168 168 VAL VAL B . n 
B 1 169 PHE 169 169 169 PHE PHE B . n 
B 1 170 GLY 170 170 170 GLY GLY B . n 
B 1 171 THR 171 171 171 THR THR B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 GLY 173 173 173 GLY GLY B . n 
B 1 174 VAL 174 174 174 VAL VAL B . n 
B 1 175 LEU 175 175 175 LEU LEU B . n 
B 1 176 ILE 176 176 176 ILE ILE B . n 
B 1 177 PHE 177 177 177 PHE PHE B . n 
B 1 178 LEU 178 178 178 LEU LEU B . n 
B 1 179 ARG 179 179 179 ARG ARG B . n 
B 1 180 ASP 180 180 180 ASP ASP B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 MET 182 182 182 MET MET B . n 
B 1 183 PRO 183 183 183 PRO PRO B . n 
B 1 184 LYS 184 184 184 LYS LYS B . n 
B 1 185 LEU 185 185 185 LEU LEU B . n 
B 1 186 MET 186 186 186 MET MET B . n 
B 1 187 HIS 187 187 187 HIS HIS B . n 
B 1 188 ILE 188 188 188 ILE ILE B . n 
B 1 189 ASP 189 189 189 ASP ASP B . n 
B 1 190 LEU 190 190 190 LEU LEU B . n 
B 1 191 LYS 191 191 191 LYS LYS B . n 
B 1 192 LYS 192 192 192 LYS LYS B . n 
B 1 193 GLN 193 193 193 GLN GLN B . n 
B 1 194 ALA 194 194 194 ALA ALA B . n 
B 1 195 VAL 195 195 195 VAL VAL B . n 
B 1 196 LYS 196 196 196 LYS LYS B . n 
B 1 197 THR 197 197 197 THR THR B . n 
B 1 198 ALA 198 198 198 ALA ALA B . n 
B 1 199 LYS 199 199 199 LYS LYS B . n 
B 1 200 GLU 200 200 200 GLU GLU B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 ASP 202 202 202 ASP ASP B . n 
B 1 203 MET 203 203 203 MET MET B . n 
B 1 204 ILE 204 204 204 ILE ILE B . n 
B 1 205 PRO 205 205 205 PRO PRO B . n 
B 1 206 VAL 206 206 206 VAL VAL B . n 
B 1 207 PRO 207 207 207 PRO PRO B . n 
B 1 208 VAL 208 208 208 VAL VAL B . n 
B 1 209 ILE 209 209 209 ILE ILE B . n 
B 1 210 VAL 210 210 210 VAL VAL B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 SER 212 212 212 SER SER B . n 
B 1 213 THR 213 213 213 THR THR B . n 
B 1 214 HIS 214 214 214 HIS HIS B . n 
B 1 215 PHE 215 215 215 PHE PHE B . n 
B 1 216 TYR 216 216 216 TYR TYR B . n 
B 1 217 THR 217 217 217 THR THR B . n 
B 1 218 ILE 218 218 218 ILE ILE B . n 
B 1 219 ASN 219 219 219 ASN ASN B . n 
B 1 220 ASP 220 220 220 ASP ASP B . n 
B 1 221 GLY 221 221 221 GLY GLY B . n 
B 1 222 SER 222 222 222 SER SER B . n 
B 1 223 SER 223 223 223 SER SER B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 ILE 225 225 225 ILE ILE B . n 
B 1 226 GLY 226 226 226 GLY GLY B . n 
B 1 227 GLN 227 227 227 GLN GLN B . n 
B 1 228 THR 228 228 228 THR THR B . n 
B 1 229 LEU 229 229 229 LEU LEU B . n 
B 1 230 GLY 230 230 230 GLY GLY B . n 
B 1 231 THR 231 231 231 THR THR B . n 
B 1 232 VAL 232 232 232 VAL VAL B . n 
B 1 233 ASN 233 233 233 ASN ASN B . n 
B 1 234 THR 234 234 234 THR THR B . n 
B 1 235 LYS 235 235 235 LYS LYS B . n 
B 1 236 PHE 236 236 236 PHE PHE B . n 
B 1 237 ALA 237 237 237 ALA ALA B . n 
B 1 238 LYS 238 238 238 LYS LYS B . n 
B 1 239 GLY 239 239 239 GLY GLY B . n 
B 1 240 LEU 240 240 240 LEU LEU B . n 
B 1 241 VAL 241 241 241 VAL VAL B . n 
B 1 242 ALA 242 242 242 ALA ALA B . n 
B 1 243 ALA 243 243 243 ALA ALA B . n 
B 1 244 GLY 244 244 244 GLY GLY B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 ASN 246 246 246 ASN ASN B . n 
B 1 247 ASP 247 247 247 ASP ASP B . n 
B 1 248 SER 248 248 248 SER SER B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 ASP 250 250 250 ASP ASP B . n 
B 1 251 MET 251 251 251 MET MET B . n 
B 1 252 ALA 252 252 252 ALA ALA B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 ILE 255 255 255 ILE ILE B . n 
B 1 256 ASN 256 256 256 ASN ASN B . n 
B 1 257 ALA 257 257 257 ALA ALA B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 ASP 259 259 259 ASP ASP B . n 
B 1 260 VAL 260 260 260 VAL VAL B . n 
B 1 261 LEU 261 261 261 LEU LEU B . n 
B 1 262 ALA 262 262 262 ALA ALA B . n 
B 1 263 ILE 263 263 263 ILE ILE B . n 
B 1 264 SER 264 264 264 SER SER B . n 
B 1 265 GLY 265 265 265 GLY GLY B . n 
B 1 266 GLY 266 266 266 GLY GLY B . n 
B 1 267 ILE 267 267 267 ILE ILE B . n 
B 1 268 ASP 268 268 268 ASP ASP B . n 
B 1 269 GLU 269 269 269 GLU GLU B . n 
B 1 270 ILE 270 270 270 ILE ILE B . n 
B 1 271 GLY 271 271 271 GLY GLY B . n 
B 1 272 ARG 272 272 272 ARG ARG B . n 
B 1 273 ALA 273 273 273 ALA ALA B . n 
B 1 274 VAL 274 274 274 VAL VAL B . n 
B 1 275 GLN 275 275 275 GLN GLN B . n 
B 1 276 GLU 276 276 276 GLU GLU B . n 
B 1 277 PHE 277 277 277 PHE PHE B . n 
B 1 278 ASN 278 278 278 ASN ASN B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 LEU 280 280 280 LEU LEU B . n 
B 1 281 GLU 281 281 281 GLU GLU B . n 
B 1 282 VAL 282 282 282 VAL VAL B . n 
B 1 283 THR 283 283 283 THR THR B . n 
B 1 284 GLY 284 284 284 GLY GLY B . n 
B 1 285 LYS 285 285 285 LYS LYS B . n 
B 1 286 THR 286 286 286 THR THR B . n 
B 1 287 LYS 287 287 287 LYS LYS B . n 
B 1 288 ALA 288 288 288 ALA ALA B . n 
B 1 289 TYR 289 289 289 TYR TYR B . n 
B 1 290 VAL 290 290 290 VAL VAL B . n 
B 1 291 SER 291 291 291 SER SER B . n 
B 1 292 LYS 292 292 292 LYS LYS B . n 
B 1 293 GLN 293 293 293 GLN GLN B . n 
B 1 294 VAL 294 294 294 VAL VAL B . n 
B 1 295 VAL 295 295 295 VAL VAL B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 LYS 297 297 297 LYS LYS B . n 
B 1 298 LYS 298 298 298 LYS LYS B . n 
B 1 299 ASN 299 299 299 ASN ASN B . n 
B 1 300 PHE 300 300 300 PHE PHE B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 ALA 302 302 302 ALA ALA B . n 
B 1 303 ASP 303 303 303 ASP ASP B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 LEU 305 305 305 LEU LEU B . n 
B 1 306 LYS 306 306 306 LYS LYS B . n 
B 1 307 ASN 307 307 307 ASN ASN B . n 
B 1 308 ALA 308 308 308 ALA ALA B . n 
B 1 309 GLN 309 309 309 GLN GLN B . n 
B 1 310 ASP 310 310 310 ASP ASP B . n 
B 1 311 LYS 311 311 311 LYS LYS B . n 
B 1 312 GLY 312 312 312 GLY GLY B . n 
B 1 313 VAL 313 313 313 VAL VAL B . n 
B 1 314 LEU 314 314 314 LEU LEU B . n 
B 1 315 VAL 315 315 315 VAL VAL B . n 
B 1 316 ALA 316 316 316 ALA ALA B . n 
B 1 317 THR 317 317 317 THR THR B . n 
B 1 318 LEU 318 318 318 LEU LEU B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 GLY 320 320 320 GLY GLY B . n 
B 1 321 ASP 321 321 321 ASP ASP B . n 
B 1 322 VAL 322 322 322 VAL VAL B . n 
B 1 323 MET 323 323 323 MET MET B . n 
B 1 324 ASP 324 324 324 ASP ASP B . n 
B 1 325 PRO 325 325 325 PRO PRO B . n 
B 1 326 ALA 326 326 326 ALA ALA B . n 
B 1 327 GLN 327 327 327 GLN GLN B . n 
B 1 328 PHE 328 328 328 PHE PHE B . n 
B 1 329 SER 329 329 329 SER SER B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 LEU 331 331 331 LEU LEU B . n 
B 1 332 LYS 332 332 332 LYS LYS B . n 
B 1 333 PRO 333 333 333 PRO PRO B . n 
B 1 334 ALA 334 334 334 ALA ALA B . n 
B 1 335 GLU 335 335 335 GLU GLU B . n 
B 1 336 SER 336 336 336 SER SER B . n 
B 1 337 VAL 337 337 337 VAL VAL B . n 
B 1 338 THR 338 338 338 THR THR B . n 
B 1 339 LEU 339 339 339 LEU LEU B . n 
B 1 340 VAL 340 340 340 VAL VAL B . n 
B 1 341 GLY 341 341 341 GLY GLY B . n 
B 1 342 GLN 342 342 342 GLN GLN B . n 
B 1 343 LYS 343 343 343 LYS LYS B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 ALA 345 345 345 ALA ALA B . n 
B 1 346 VAL 346 346 346 VAL VAL B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 GLU 348 348 348 GLU GLU B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 GLN 350 350 350 GLN GLN B . n 
B 1 351 SER 351 351 351 SER SER B . n 
B 1 352 GLN 352 352 352 GLN GLN B . n 
B 1 353 LEU 353 353 353 LEU LEU B . n 
B 1 354 GLY 354 354 354 GLY GLY B . n 
B 1 355 ARG 355 355 355 ARG ARG B . n 
B 1 356 LEU 356 356 356 LEU LEU B . n 
B 1 357 ARG 357 357 357 ARG ARG B . n 
B 1 358 ALA 358 358 358 ALA ALA B . n 
B 1 359 ALA 359 359 359 ALA ALA B . n 
B 1 360 GLU 360 360 360 GLU GLU B . n 
B 1 361 ASN 361 361 361 ASN ASN B . n 
B 1 362 ILE 362 362 362 ILE ILE B . n 
B 1 363 ILE 363 363 363 ILE ILE B . n 
B 1 364 ASN 364 364 364 ASN ASN B . n 
B 1 365 TYR 365 365 365 TYR TYR B . n 
B 1 366 SER 366 366 366 SER SER B . n 
B 1 367 TRP 367 367 367 TRP TRP B . n 
B 1 368 PHE 368 368 368 PHE PHE B . n 
B 1 369 ALA 369 369 369 ALA ALA B . n 
B 1 370 LEU 370 370 370 LEU LEU B . n 
B 1 371 GLY 371 371 371 GLY GLY B . n 
B 1 372 ILE 372 372 372 ILE ILE B . n 
B 1 373 ALA 373 373 373 ALA ALA B . n 
B 1 374 LEU 374 374 374 LEU LEU B . n 
B 1 375 SER 375 375 375 SER SER B . n 
B 1 376 ALA 376 376 376 ALA ALA B . n 
B 1 377 ALA 377 377 377 ALA ALA B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 GLY 379 379 379 GLY GLY B . n 
B 1 380 ILE 380 380 380 ILE ILE B . n 
B 1 381 VAL 381 381 381 VAL VAL B . n 
B 1 382 GLY 382 382 382 GLY GLY B . n 
B 1 383 THR 383 383 383 THR THR B . n 
B 1 384 LYS 384 384 384 LYS LYS B . n 
B 1 385 VAL 385 385 385 VAL VAL B . n 
B 1 386 SER 386 386 386 SER SER B . n 
B 1 387 GLY 387 387 387 GLY GLY B . n 
B 1 388 VAL 388 388 388 VAL VAL B . n 
B 1 389 PRO 389 389 389 PRO PRO B . n 
B 1 390 ILE 390 390 390 ILE ILE B . n 
B 1 391 ALA 391 391 391 ALA ALA B . n 
B 1 392 LEU 392 392 392 LEU LEU B . n 
B 1 393 GLY 393 393 393 GLY GLY B . n 
B 1 394 GLY 394 394 394 GLY GLY B . n 
B 1 395 GLY 395 395 395 GLY GLY B . n 
B 1 396 THR 396 396 396 THR THR B . n 
B 1 397 ALA 397 397 397 ALA ALA B . n 
B 1 398 SER 398 398 398 SER SER B . n 
B 1 399 LEU 399 399 399 LEU LEU B . n 
B 1 400 ILE 400 400 400 ILE ILE B . n 
B 1 401 VAL 401 401 401 VAL VAL B . n 
B 1 402 GLY 402 402 402 GLY GLY B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 VAL 404 404 404 VAL VAL B . n 
B 1 405 GLN 405 405 405 GLN GLN B . n 
B 1 406 SER 406 406 406 SER SER B . n 
B 1 407 ILE 407 407 407 ILE ILE B . n 
B 1 408 TYR 408 408 408 TYR TYR B . n 
B 1 409 ARG 409 409 409 ARG ARG B . n 
B 1 410 ASP 410 410 410 ASP ASP B . n 
B 1 411 LYS 411 411 411 LYS LYS B . n 
B 1 412 HIS 412 412 412 HIS HIS B . n 
B 1 413 ALA 413 413 413 ALA ALA B . n 
B 1 414 HIS 414 414 414 HIS HIS B . n 
B 1 415 MET 415 415 415 MET MET B . n 
B 1 416 ASP 416 416 416 ASP ASP B . n 
B 1 417 THR 417 417 417 THR THR B . n 
B 1 418 ILE 418 418 418 ILE ILE B . n 
B 1 419 PRO 419 419 419 PRO PRO B . n 
B 1 420 ASP 420 420 420 ASP ASP B . n 
B 1 421 SER 421 421 421 SER SER B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 LEU 423 423 423 LEU LEU B . n 
B 1 424 GLU 424 424 424 GLU GLU B . n 
B 1 425 PHE 425 425 425 PHE PHE B . n 
B 1 426 PHE 426 426 426 PHE PHE B . n 
B 1 427 GLN 427 427 427 GLN GLN B . n 
B 1 428 SER 428 428 428 SER SER B . n 
B 1 429 ILE 429 429 429 ILE ILE B . n 
B 1 430 GLY 430 430 430 GLY GLY B . n 
B 1 431 LEU 431 431 431 LEU LEU B . n 
B 1 432 ASN 432 432 432 ASN ASN B . n 
B 1 433 LEU 433 433 433 LEU LEU B . n 
B 1 434 PHE 434 434 434 PHE PHE B . n 
B 1 435 ILE 435 435 435 ILE ILE B . n 
B 1 436 ALA 436 436 436 ALA ALA B . n 
B 1 437 THR 437 437 437 THR THR B . n 
B 1 438 VAL 438 438 438 VAL VAL B . n 
B 1 439 GLY 439 439 439 GLY GLY B . n 
B 1 440 LEU 440 440 440 LEU LEU B . n 
B 1 441 SER 441 441 441 SER SER B . n 
B 1 442 ALA 442 442 442 ALA ALA B . n 
B 1 443 ALA 443 443 443 ALA ALA B . n 
B 1 444 LYS 444 444 444 LYS LYS B . n 
B 1 445 THR 445 445 445 THR THR B . n 
B 1 446 PHE 446 446 446 PHE PHE B . n 
B 1 447 ILE 447 447 447 ILE ILE B . n 
B 1 448 SER 448 448 448 SER SER B . n 
B 1 449 ALA 449 449 449 ALA ALA B . n 
B 1 450 ILE 450 450 450 ILE ILE B . n 
B 1 451 GLN 451 451 451 GLN GLN B . n 
B 1 452 SER 452 452 452 SER SER B . n 
B 1 453 MET 453 453 453 MET MET B . n 
B 1 454 GLY 454 454 454 GLY GLY B . n 
B 1 455 ILE 455 455 455 ILE ILE B . n 
B 1 456 SER 456 456 456 SER SER B . n 
B 1 457 VAL 457 457 457 VAL VAL B . n 
B 1 458 LEU 458 458 458 LEU LEU B . n 
B 1 459 LEU 459 459 459 LEU LEU B . n 
B 1 460 ILE 460 460 460 ILE ILE B . n 
B 1 461 GLY 461 461 461 GLY GLY B . n 
B 1 462 ALA 462 462 462 ALA ALA B . n 
B 1 463 VAL 463 463 463 VAL VAL B . n 
B 1 464 ILE 464 464 464 ILE ILE B . n 
B 1 465 SER 465 465 465 SER SER B . n 
B 1 466 ILE 466 466 466 ILE ILE B . n 
B 1 467 LEU 467 467 467 LEU LEU B . n 
B 1 468 PRO 468 468 468 PRO PRO B . n 
B 1 469 HIS 469 469 469 HIS HIS B . n 
B 1 470 ILE 470 470 470 ILE ILE B . n 
B 1 471 ILE 471 471 471 ILE ILE B . n 
B 1 472 THR 472 472 472 THR THR B . n 
B 1 473 PHE 473 473 473 PHE PHE B . n 
B 1 474 VAL 474 474 474 VAL VAL B . n 
B 1 475 ILE 475 475 475 ILE ILE B . n 
B 1 476 CYS 476 476 476 CYS ALA B . n 
B 1 477 TYR 477 477 477 TYR TYR B . n 
B 1 478 TYR 478 478 478 TYR TYR B . n 
B 1 479 LEU 479 479 479 LEU LEU B . n 
B 1 480 MET 480 480 480 MET MET B . n 
B 1 481 LYS 481 481 481 LYS LYS B . n 
B 1 482 MET 482 482 482 MET MET B . n 
B 1 483 GLU 483 483 483 GLU GLU B . n 
B 1 484 PRO 484 484 484 PRO PRO B . n 
B 1 485 ILE 485 485 485 ILE ILE B . n 
B 1 486 SER 486 486 486 SER SER B . n 
B 1 487 ILE 487 487 487 ILE ILE B . n 
B 1 488 ILE 488 488 488 ILE ILE B . n 
B 1 489 GLY 489 489 489 GLY GLY B . n 
B 1 490 ALA 490 490 490 ALA ALA B . n 
B 1 491 GLN 491 491 491 GLN GLN B . n 
B 1 492 THR 492 492 492 THR THR B . n 
B 1 493 GLY 493 493 493 GLY GLY B . n 
B 1 494 ALA 494 494 494 ALA ALA B . n 
B 1 495 ASP 495 495 495 ASP ASP B . n 
B 1 496 THR 496 496 496 THR THR B . n 
B 1 497 LEU 497 497 497 LEU LEU B . n 
B 1 498 SER 498 498 498 SER SER B . n 
B 1 499 ALA 499 499 499 ALA ALA B . n 
B 1 500 ALA 500 500 500 ALA ALA B . n 
B 1 501 LEU 501 501 501 LEU LEU B . n 
B 1 502 ASN 502 502 502 ASN ASN B . n 
B 1 503 ASP 503 503 503 ASP ASP B . n 
B 1 504 VAL 504 504 504 VAL VAL B . n 
B 1 505 SER 505 505 505 SER SER B . n 
B 1 506 GLU 506 506 506 GLU GLU B . n 
B 1 507 ARG 507 507 507 ARG ARG B . n 
B 1 508 VAL 508 508 508 VAL VAL B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 SER 510 510 510 SER SER B . n 
B 1 511 ASP 511 511 511 ASP ASP B . n 
B 1 512 ALA 512 512 512 ALA ALA B . n 
B 1 513 SER 513 513 513 SER SER B . n 
B 1 514 PRO 514 514 514 PRO PRO B . n 
B 1 515 PHE 515 515 515 PHE PHE B . n 
B 1 516 PHE 516 516 516 PHE PHE B . n 
B 1 517 ALA 517 517 517 ALA ALA B . n 
B 1 518 ALA 518 518 518 ALA ALA B . n 
B 1 519 ALA 519 519 519 ALA ALA B . n 
B 1 520 VAL 520 520 520 VAL VAL B . n 
B 1 521 ALA 521 521 521 ALA ALA B . n 
B 1 522 PRO 522 522 522 PRO PRO B . n 
B 1 523 ALA 523 523 523 ALA ALA B . n 
B 1 524 TYR 524 524 524 TYR TYR B . n 
B 1 525 ALA 525 525 525 ALA ALA B . n 
B 1 526 ILE 526 526 526 ILE ILE B . n 
B 1 527 GLY 527 527 527 GLY GLY B . n 
B 1 528 ASN 528 528 528 ASN ASN B . n 
B 1 529 ILE 529 529 529 ILE ILE B . n 
B 1 530 PHE 530 530 530 PHE PHE B . n 
B 1 531 LEU 531 531 531 LEU LEU B . n 
B 1 532 THR 532 532 532 THR THR B . n 
B 1 533 LEU 533 533 533 LEU LEU B . n 
B 1 534 MET 534 534 534 MET MET B . n 
B 1 535 GLY 535 535 535 GLY GLY B . n 
B 1 536 PRO 536 536 536 PRO PRO B . n 
B 1 537 ILE 537 537 537 ILE ILE B . n 
B 1 538 PHE 538 538 538 PHE PHE B . n 
B 1 539 ILE 539 539 539 ILE ILE B . n 
B 1 540 VAL 540 540 540 VAL VAL B . n 
B 1 541 LEU 541 541 541 LEU LEU B . n 
B 1 542 LEU 542 542 542 LEU LEU B . n 
B 1 543 SER 543 543 543 SER SER B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ASP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ASP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 ASP 1 601 601 ASP ASP A . 
D 2 ASP 1 601 601 ASP ASP B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A CYS 19  ? SG ? A CYS 19  SG 
2 1 Y 1 A CYS 110 ? SG ? A CYS 110 SG 
3 1 Y 1 A CYS 476 ? SG ? A CYS 476 SG 
4 1 Y 1 B CYS 19  ? SG ? B CYS 19  SG 
5 1 Y 1 B CYS 110 ? SG ? B CYS 110 SG 
6 1 Y 1 B CYS 476 ? SG ? B CYS 476 SG 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8Y1X 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8Y1X 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8Y1X 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8Y1X 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 8218  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.650  ? 11162 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 15.439 ? 2876  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.046  ? 1386  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1382  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8Y1X 
_struct.title                        'Cryo-EM structure of the aspartate:alanine antiporter AspT WT' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8Y1X 
_struct_keywords.text            'amino acid, antiporter, elevator mechanism, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ASPT_TETHA 
_struct_ref.pdbx_db_accession          Q8L3K8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MNAIGNFLVGTPVFTIFICLALGYLLGKLKIGSFTLGATVGVLIVALLIGQLGVFPRDTLLGDIFFDFFMFAIGYRVGPS
FISSMKKFGAKIVYATLIFLVSAFIVAYACFKMFHIGPGIAAGIIAGGLTQSAVIGSSLETISKLPISDHLKTLYSNQIP
IVYTLTYVFGTIGVLIFLRDIMPKLMHIDLKKQAVKTAKELDMIPVPVIVASTHFYTINDGSSLIGQTLGTVNTKFAKGL
VAAGLNDSADMASVINAGDVLAISGGIDEIGRAVQEFNLLEVTGKTKAYVSKQVVLKKNFSADVLKNAQDKGVLVATLAG
DVMDPAQFSTLKPAESVTLVGQKDAVSEVQSQLGRLRAAENIINYSWFALGIALSAALGIVGTKVSGVPIALGGGTASLI
VGLVQSIYRDKHAHMDTIPDSLLEFFQSIGLNLFIATVGLSAAKTFISAIQSMGISVLLIGAVISILPHIITFVICYYLM
KMEPISIIGAQTGADTLSAALNDVSERVGSDASPFFAAAVAPAYAIGNIFLTLMGPIFIVLLS
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8Y1X A 1 ? 543 ? Q8L3K8 1 ? 543 ? 1 543 
2 1 8Y1X B 1 ? 543 ? Q8L3K8 1 ? 543 ? 1 543 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 MET A 1   ? THR A 11  ? MET A 1   THR A 11  1 ? 11 
HELX_P HELX_P2  AA2 THR A 11  ? CYS A 19  ? THR A 11  CYS A 19  1 ? 9  
HELX_P HELX_P3  AA3 LEU A 20  ? LEU A 29  ? LEU A 20  LEU A 29  1 ? 10 
HELX_P HELX_P4  AA4 GLY A 37  ? GLY A 50  ? GLY A 37  GLY A 50  1 ? 14 
HELX_P HELX_P5  AA5 ASP A 58  ? PHE A 88  ? ASP A 58  PHE A 88  1 ? 31 
HELX_P HELX_P6  AA6 ALA A 90  ? HIS A 115 ? ALA A 90  HIS A 115 1 ? 26 
HELX_P HELX_P7  AA7 GLY A 117 ? LEU A 129 ? GLY A 117 LEU A 129 1 ? 13 
HELX_P HELX_P8  AA8 SER A 132 ? LEU A 145 ? SER A 132 LEU A 145 1 ? 14 
HELX_P HELX_P9  AA9 SER A 148 ? ASP A 180 ? SER A 148 ASP A 180 1 ? 33 
HELX_P HELX_P10 AB1 ASP A 180 ? HIS A 187 ? ASP A 180 HIS A 187 1 ? 8  
HELX_P HELX_P11 AB2 ASP A 189 ? LEU A 201 ? ASP A 189 LEU A 201 1 ? 13 
HELX_P HELX_P12 AB3 THR A 228 ? PHE A 236 ? THR A 228 PHE A 236 1 ? 9  
HELX_P HELX_P13 AB4 GLY A 266 ? PHE A 277 ? GLY A 266 PHE A 277 1 ? 12 
HELX_P HELX_P14 AB5 ALA A 302 ? GLY A 312 ? ALA A 302 GLY A 312 1 ? 11 
HELX_P HELX_P15 AB6 ASP A 324 ? SER A 329 ? ASP A 324 SER A 329 5 ? 6  
HELX_P HELX_P16 AB7 ASP A 344 ? GLY A 354 ? ASP A 344 GLY A 354 1 ? 11 
HELX_P HELX_P17 AB8 ASN A 364 ? VAL A 381 ? ASN A 364 VAL A 381 1 ? 18 
HELX_P HELX_P18 AB9 GLY A 393 ? HIS A 412 ? GLY A 393 HIS A 412 1 ? 20 
HELX_P HELX_P19 AC1 PRO A 419 ? ALA A 442 ? PRO A 419 ALA A 442 1 ? 24 
HELX_P HELX_P20 AC2 THR A 445 ? MET A 453 ? THR A 445 MET A 453 1 ? 9  
HELX_P HELX_P21 AC3 LEU A 458 ? TYR A 478 ? LEU A 458 TYR A 478 1 ? 21 
HELX_P HELX_P22 AC4 GLU A 483 ? ASP A 495 ? GLU A 483 ASP A 495 1 ? 13 
HELX_P HELX_P23 AC5 LEU A 497 ? GLY A 509 ? LEU A 497 GLY A 509 1 ? 13 
HELX_P HELX_P24 AC6 ALA A 512 ? SER A 543 ? ALA A 512 SER A 543 1 ? 32 
HELX_P HELX_P25 AC7 ASN B 2   ? THR B 11  ? ASN B 2   THR B 11  1 ? 10 
HELX_P HELX_P26 AC8 THR B 11  ? CYS B 19  ? THR B 11  CYS B 19  1 ? 9  
HELX_P HELX_P27 AC9 LEU B 20  ? LEU B 29  ? LEU B 20  LEU B 29  1 ? 10 
HELX_P HELX_P28 AD1 GLY B 37  ? GLY B 50  ? GLY B 37  GLY B 50  1 ? 14 
HELX_P HELX_P29 AD2 ASP B 58  ? PHE B 88  ? ASP B 58  PHE B 88  1 ? 31 
HELX_P HELX_P30 AD3 ALA B 90  ? HIS B 115 ? ALA B 90  HIS B 115 1 ? 26 
HELX_P HELX_P31 AD4 GLY B 117 ? LEU B 129 ? GLY B 117 LEU B 129 1 ? 13 
HELX_P HELX_P32 AD5 SER B 132 ? LEU B 145 ? SER B 132 LEU B 145 1 ? 14 
HELX_P HELX_P33 AD6 SER B 148 ? ASP B 180 ? SER B 148 ASP B 180 1 ? 33 
HELX_P HELX_P34 AD7 ASP B 180 ? HIS B 187 ? ASP B 180 HIS B 187 1 ? 8  
HELX_P HELX_P35 AD8 ASP B 189 ? LEU B 201 ? ASP B 189 LEU B 201 1 ? 13 
HELX_P HELX_P36 AD9 THR B 228 ? PHE B 236 ? THR B 228 PHE B 236 1 ? 9  
HELX_P HELX_P37 AE1 GLY B 266 ? PHE B 277 ? GLY B 266 PHE B 277 1 ? 12 
HELX_P HELX_P38 AE2 ALA B 302 ? GLY B 312 ? ALA B 302 GLY B 312 1 ? 11 
HELX_P HELX_P39 AE3 ASP B 324 ? SER B 329 ? ASP B 324 SER B 329 5 ? 6  
HELX_P HELX_P40 AE4 ASP B 344 ? GLY B 354 ? ASP B 344 GLY B 354 1 ? 11 
HELX_P HELX_P41 AE5 ASN B 364 ? VAL B 381 ? ASN B 364 VAL B 381 1 ? 18 
HELX_P HELX_P42 AE6 GLY B 393 ? HIS B 412 ? GLY B 393 HIS B 412 1 ? 20 
HELX_P HELX_P43 AE7 PRO B 419 ? ALA B 442 ? PRO B 419 ALA B 442 1 ? 24 
HELX_P HELX_P44 AE8 THR B 445 ? MET B 453 ? THR B 445 MET B 453 1 ? 9  
HELX_P HELX_P45 AE9 LEU B 458 ? TYR B 478 ? LEU B 458 TYR B 478 1 ? 21 
HELX_P HELX_P46 AF1 GLU B 483 ? ASP B 495 ? GLU B 483 ASP B 495 1 ? 13 
HELX_P HELX_P47 AF2 LEU B 497 ? GLY B 509 ? LEU B 497 GLY B 509 1 ? 13 
HELX_P HELX_P48 AF3 ALA B 512 ? SER B 543 ? ALA B 512 SER B 543 1 ? 32 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 3 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 3 ? 
AB1 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AB1 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 30  ? ILE A 31  ? LYS A 30  ILE A 31  
AA1 2 PHE A 34  ? THR A 35  ? PHE A 34  THR A 35  
AA2 1 SER A 212 ? HIS A 214 ? SER A 212 HIS A 214 
AA2 2 ILE A 263 ? GLY A 265 ? ILE A 263 GLY A 265 
AA2 3 VAL A 241 ? ALA A 242 ? VAL A 241 ALA A 242 
AA3 1 TYR A 216 ? THR A 217 ? TYR A 216 THR A 217 
AA3 2 LEU A 280 ? GLU A 281 ? LEU A 280 GLU A 281 
AA4 1 LYS A 292 ? VAL A 294 ? LYS A 292 VAL A 294 
AA4 2 VAL A 337 ? VAL A 340 ? VAL A 337 VAL A 340 
AA4 3 LEU A 314 ? THR A 317 ? LEU A 314 THR A 317 
AA5 1 GLY A 382 ? VAL A 385 ? GLY A 382 VAL A 385 
AA5 2 VAL A 388 ? ALA A 391 ? VAL A 388 ALA A 391 
AA6 1 LYS B 30  ? ILE B 31  ? LYS B 30  ILE B 31  
AA6 2 PHE B 34  ? THR B 35  ? PHE B 34  THR B 35  
AA7 1 SER B 212 ? HIS B 214 ? SER B 212 HIS B 214 
AA7 2 ILE B 263 ? GLY B 265 ? ILE B 263 GLY B 265 
AA7 3 VAL B 241 ? ALA B 242 ? VAL B 241 ALA B 242 
AA8 1 TYR B 216 ? THR B 217 ? TYR B 216 THR B 217 
AA8 2 LEU B 280 ? GLU B 281 ? LEU B 280 GLU B 281 
AA9 1 LYS B 292 ? VAL B 294 ? LYS B 292 VAL B 294 
AA9 2 VAL B 337 ? VAL B 340 ? VAL B 337 VAL B 340 
AA9 3 LEU B 314 ? THR B 317 ? LEU B 314 THR B 317 
AB1 1 GLY B 382 ? VAL B 385 ? GLY B 382 VAL B 385 
AB1 2 VAL B 388 ? ALA B 391 ? VAL B 388 ALA B 391 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 31  ? N ILE A 31  O PHE A 34  ? O PHE A 34  
AA2 1 2 N HIS A 214 ? N HIS A 214 O ILE A 263 ? O ILE A 263 
AA2 2 3 O SER A 264 ? O SER A 264 N VAL A 241 ? N VAL A 241 
AA3 1 2 N THR A 217 ? N THR A 217 O LEU A 280 ? O LEU A 280 
AA4 1 2 N VAL A 294 ? N VAL A 294 O VAL A 337 ? O VAL A 337 
AA4 2 3 O THR A 338 ? O THR A 338 N ALA A 316 ? N ALA A 316 
AA5 1 2 N THR A 383 ? N THR A 383 O ILE A 390 ? O ILE A 390 
AA6 1 2 N ILE B 31  ? N ILE B 31  O PHE B 34  ? O PHE B 34  
AA7 1 2 N HIS B 214 ? N HIS B 214 O ILE B 263 ? O ILE B 263 
AA7 2 3 O SER B 264 ? O SER B 264 N VAL B 241 ? N VAL B 241 
AA8 1 2 N THR B 217 ? N THR B 217 O LEU B 280 ? O LEU B 280 
AA9 1 2 N VAL B 294 ? N VAL B 294 O VAL B 337 ? O VAL B 337 
AA9 2 3 O THR B 338 ? O THR B 338 N ALA B 316 ? N ALA B 316 
AB1 1 2 N THR B 383 ? N THR B 383 O ILE B 390 ? O ILE B 390 
# 
_pdbx_entry_details.entry_id                   8Y1X 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 223 ? ? 71.03   -5.15   
2  1 ASN A 246 ? ? 52.68   -127.22 
3  1 ASN A 256 ? ? -95.53  -65.38  
4  1 ALA A 257 ? ? -170.48 126.25  
5  1 PHE A 300 ? ? 38.25   59.24   
6  1 ALA A 443 ? ? -133.61 -35.62  
7  1 SER B 223 ? ? 71.10   -5.16   
8  1 ASN B 246 ? ? 52.66   -127.25 
9  1 ASN B 256 ? ? -95.54  -65.38  
10 1 ALA B 257 ? ? -170.42 126.22  
11 1 PHE B 300 ? ? 38.27   59.16   
12 1 ASP B 321 ? ? -170.04 148.51  
13 1 ALA B 443 ? ? -133.65 -35.65  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8Y1X 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'BACKBONE TRACE' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   AlphaFold 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    8Y1X 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               125465 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            6.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'aspartate:alanine antiporter AspT' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8Y1X 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           96000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            50 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   400 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8Y1X 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              80 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   277 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8Y1X 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8Y1X 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C2 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-25 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8Y1X 
_em_admin.last_update        2025-01-29 
_em_admin.map_release_date   2025-01-29 
_em_admin.title              'Cryo-EM structure of the aspartate:alanine antiporter AspT WT' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 20    mM MES   1 '2-(N-morpholino)ethanesulfonic acid' 
1 100   mM NaCl  2 'sodium chloride'                     
1 0.003 %  LMNG  3 'Lauryl maltose neopentyl glycol'     
1 100   mM L-Asp 4 'L-aspartic acid'                     
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.058 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          51669 
_em_entity_assembly_naturalsource.organism             'Tetragenococcus halophilus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               D10 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              pTrc99a 
_em_entity_assembly_recombinant.strain               'C43(DE3)' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               30.6 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         40 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'FEI FALCON III (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    8 
_em_image_recording.num_real_images                     12357 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1636712 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? crYOLO    ?            
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       ?            
MASKING                    ? 3  ? ? ? ?         ?            
'CTF CORRECTION'           ? 4  1 ? ? RELION    ?            
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?            
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?            
'MODEL FITTING'            ? 7  ? 1 ? Coot      ?            
OTHER                      ? 8  ? ? ? ?         ?            
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? RELION    ?            
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? cryoSPARC ?            
CLASSIFICATION             ? 11 1 ? ? cryoSPARC ?            
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC ?            
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX    1.20.1_4487: 
# 
_em_specimen.concentration           2.83 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Japan Society for the Promotion of Science (JSPS)'        Japan 16K07653      1 
'Japan Society for the Promotion of Science (JSPS)'        Japan 20K05779      2 
'Japan Society for the Promotion of Science (JSPS)'        Japan 23K05004      3 
'Japan Agency for Medical Research and Development (AMED)' Japan JP23ama121019 4 
'Japan Agency for Medical Research and Development (AMED)' Japan JP23ama121038 5 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    8Y1X 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . MET A 1 1   ? 102.989 134.943 136.902 1.00 86.93  ? 1   MET A N   1 
ATOM   2    C CA  . MET A 1 1   ? 104.397 134.570 136.847 1.00 86.93  ? 1   MET A CA  1 
ATOM   3    C C   . MET A 1 1   ? 104.590 133.147 137.357 1.00 86.93  ? 1   MET A C   1 
ATOM   4    O O   . MET A 1 1   ? 105.444 132.409 136.868 1.00 86.93  ? 1   MET A O   1 
ATOM   5    C CB  . MET A 1 1   ? 105.244 135.548 137.662 1.00 86.93  ? 1   MET A CB  1 
ATOM   6    C CG  . MET A 1 1   ? 105.311 136.946 137.069 1.00 86.93  ? 1   MET A CG  1 
ATOM   7    S SD  . MET A 1 1   ? 105.220 136.943 135.269 1.00 86.93  ? 1   MET A SD  1 
ATOM   8    C CE  . MET A 1 1   ? 106.378 138.250 134.871 1.00 86.93  ? 1   MET A CE  1 
ATOM   9    N N   . ASN A 1 2   ? 103.794 132.776 138.360 1.00 76.24  ? 2   ASN A N   1 
ATOM   10   C CA  . ASN A 1 2   ? 103.812 131.411 138.869 1.00 76.24  ? 2   ASN A CA  1 
ATOM   11   C C   . ASN A 1 2   ? 102.889 130.527 138.036 1.00 76.24  ? 2   ASN A C   1 
ATOM   12   O O   . ASN A 1 2   ? 103.180 129.341 137.842 1.00 76.24  ? 2   ASN A O   1 
ATOM   13   C CB  . ASN A 1 2   ? 103.440 131.445 140.367 1.00 76.24  ? 2   ASN A CB  1 
ATOM   14   C CG  . ASN A 1 2   ? 103.301 130.058 141.033 1.00 76.24  ? 2   ASN A CG  1 
ATOM   15   O OD1 . ASN A 1 2   ? 102.876 129.068 140.443 1.00 76.24  ? 2   ASN A OD1 1 
ATOM   16   N ND2 . ASN A 1 2   ? 103.678 130.009 142.305 1.00 76.24  ? 2   ASN A ND2 1 
ATOM   17   N N   . ALA A 1 3   ? 101.817 131.104 137.486 1.00 67.30  ? 3   ALA A N   1 
ATOM   18   C CA  . ALA A 1 3   ? 100.832 130.319 136.747 1.00 67.30  ? 3   ALA A CA  1 
ATOM   19   C C   . ALA A 1 3   ? 101.429 129.702 135.487 1.00 67.30  ? 3   ALA A C   1 
ATOM   20   O O   . ALA A 1 3   ? 101.087 128.570 135.126 1.00 67.30  ? 3   ALA A O   1 
ATOM   21   C CB  . ALA A 1 3   ? 99.625  131.187 136.396 1.00 67.30  ? 3   ALA A CB  1 
ATOM   22   N N   . ILE A 1 4   ? 102.307 130.431 134.796 1.00 61.33  ? 4   ILE A N   1 
ATOM   23   C CA  . ILE A 1 4   ? 102.931 129.886 133.593 1.00 61.33  ? 4   ILE A CA  1 
ATOM   24   C C   . ILE A 1 4   ? 103.819 128.695 133.940 1.00 61.33  ? 4   ILE A C   1 
ATOM   25   O O   . ILE A 1 4   ? 103.807 127.671 133.243 1.00 61.33  ? 4   ILE A O   1 
ATOM   26   C CB  . ILE A 1 4   ? 103.704 130.988 132.843 1.00 61.33  ? 4   ILE A CB  1 
ATOM   27   C CG1 . ILE A 1 4   ? 104.530 130.388 131.704 1.00 61.33  ? 4   ILE A CG1 1 
ATOM   28   C CG2 . ILE A 1 4   ? 104.571 131.798 133.797 1.00 61.33  ? 4   ILE A CG2 1 
ATOM   29   C CD1 . ILE A 1 4   ? 103.710 130.031 130.486 1.00 61.33  ? 4   ILE A CD1 1 
ATOM   30   N N   . GLY A 1 5   ? 104.587 128.800 135.026 1.00 59.92  ? 5   GLY A N   1 
ATOM   31   C CA  . GLY A 1 5   ? 105.382 127.667 135.469 1.00 59.92  ? 5   GLY A CA  1 
ATOM   32   C C   . GLY A 1 5   ? 104.527 126.486 135.885 1.00 59.92  ? 5   GLY A C   1 
ATOM   33   O O   . GLY A 1 5   ? 104.870 125.332 135.611 1.00 59.92  ? 5   GLY A O   1 
ATOM   34   N N   . ASN A 1 6   ? 103.403 126.759 136.553 1.00 59.02  ? 6   ASN A N   1 
ATOM   35   C CA  . ASN A 1 6   ? 102.482 125.693 136.933 1.00 59.02  ? 6   ASN A CA  1 
ATOM   36   C C   . ASN A 1 6   ? 101.916 124.991 135.708 1.00 59.02  ? 6   ASN A C   1 
ATOM   37   O O   . ASN A 1 6   ? 101.819 123.761 135.680 1.00 59.02  ? 6   ASN A O   1 
ATOM   38   C CB  . ASN A 1 6   ? 101.352 126.256 137.795 1.00 59.02  ? 6   ASN A CB  1 
ATOM   39   C CG  . ASN A 1 6   ? 101.491 125.883 139.257 1.00 59.02  ? 6   ASN A CG  1 
ATOM   40   O OD1 . ASN A 1 6   ? 101.445 124.707 139.616 1.00 59.02  ? 6   ASN A OD1 1 
ATOM   41   N ND2 . ASN A 1 6   ? 101.661 126.887 140.110 1.00 59.02  ? 6   ASN A ND2 1 
ATOM   42   N N   . PHE A 1 7   ? 101.548 125.758 134.681 1.00 51.73  ? 7   PHE A N   1 
ATOM   43   C CA  . PHE A 1 7   ? 101.062 125.166 133.439 1.00 51.73  ? 7   PHE A CA  1 
ATOM   44   C C   . PHE A 1 7   ? 102.132 124.305 132.779 1.00 51.73  ? 7   PHE A C   1 
ATOM   45   O O   . PHE A 1 7   ? 101.861 123.169 132.360 1.00 51.73  ? 7   PHE A O   1 
ATOM   46   C CB  . PHE A 1 7   ? 100.603 126.279 132.496 1.00 51.73  ? 7   PHE A CB  1 
ATOM   47   C CG  . PHE A 1 7   ? 100.037 125.790 131.197 1.00 51.73  ? 7   PHE A CG  1 
ATOM   48   C CD1 . PHE A 1 7   ? 98.936  124.955 131.173 1.00 51.73  ? 7   PHE A CD1 1 
ATOM   49   C CD2 . PHE A 1 7   ? 100.598 126.186 129.996 1.00 51.73  ? 7   PHE A CD2 1 
ATOM   50   C CE1 . PHE A 1 7   ? 98.412  124.512 129.975 1.00 51.73  ? 7   PHE A CE1 1 
ATOM   51   C CE2 . PHE A 1 7   ? 100.079 125.749 128.795 1.00 51.73  ? 7   PHE A CE2 1 
ATOM   52   C CZ  . PHE A 1 7   ? 98.986  124.911 128.784 1.00 51.73  ? 7   PHE A CZ  1 
ATOM   53   N N   . LEU A 1 8   ? 103.363 124.822 132.706 1.00 49.45  ? 8   LEU A N   1 
ATOM   54   C CA  . LEU A 1 8   ? 104.442 124.094 132.047 1.00 49.45  ? 8   LEU A CA  1 
ATOM   55   C C   . LEU A 1 8   ? 104.764 122.795 132.774 1.00 49.45  ? 8   LEU A C   1 
ATOM   56   O O   . LEU A 1 8   ? 104.994 121.762 132.134 1.00 49.45  ? 8   LEU A O   1 
ATOM   57   C CB  . LEU A 1 8   ? 105.685 124.977 131.949 1.00 49.45  ? 8   LEU A CB  1 
ATOM   58   C CG  . LEU A 1 8   ? 105.612 126.138 130.954 1.00 49.45  ? 8   LEU A CG  1 
ATOM   59   C CD1 . LEU A 1 8   ? 106.696 127.163 131.247 1.00 49.45  ? 8   LEU A CD1 1 
ATOM   60   C CD2 . LEU A 1 8   ? 105.709 125.646 129.522 1.00 49.45  ? 8   LEU A CD2 1 
ATOM   61   N N   . VAL A 1 9   ? 104.786 122.821 134.108 1.00 50.31  ? 9   VAL A N   1 
ATOM   62   C CA  . VAL A 1 9   ? 105.081 121.595 134.843 1.00 50.31  ? 9   VAL A CA  1 
ATOM   63   C C   . VAL A 1 9   ? 103.876 120.655 134.839 1.00 50.31  ? 9   VAL A C   1 
ATOM   64   O O   . VAL A 1 9   ? 104.040 119.432 134.920 1.00 50.31  ? 9   VAL A O   1 
ATOM   65   C CB  . VAL A 1 9   ? 105.557 121.916 136.273 1.00 50.31  ? 9   VAL A CB  1 
ATOM   66   C CG1 . VAL A 1 9   ? 104.436 122.513 137.110 1.00 50.31  ? 9   VAL A CG1 1 
ATOM   67   C CG2 . VAL A 1 9   ? 106.138 120.675 136.943 1.00 50.31  ? 9   VAL A CG2 1 
ATOM   68   N N   . GLY A 1 10  ? 102.659 121.193 134.734 1.00 52.90  ? 10  GLY A N   1 
ATOM   69   C CA  . GLY A 1 10  ? 101.486 120.341 134.661 1.00 52.90  ? 10  GLY A CA  1 
ATOM   70   C C   . GLY A 1 10  ? 101.407 119.559 133.366 1.00 52.90  ? 10  GLY A C   1 
ATOM   71   O O   . GLY A 1 10  ? 101.011 118.390 133.362 1.00 52.90  ? 10  GLY A O   1 
ATOM   72   N N   . THR A 1 11  ? 101.778 120.187 132.249 1.00 49.51  ? 11  THR A N   1 
ATOM   73   C CA  . THR A 1 11  ? 101.687 119.524 130.951 1.00 49.51  ? 11  THR A CA  1 
ATOM   74   C C   . THR A 1 11  ? 103.077 119.282 130.379 1.00 49.51  ? 11  THR A C   1 
ATOM   75   O O   . THR A 1 11  ? 103.659 120.186 129.761 1.00 49.51  ? 11  THR A O   1 
ATOM   76   C CB  . THR A 1 11  ? 100.850 120.360 129.981 1.00 49.51  ? 11  THR A CB  1 
ATOM   77   O OG1 . THR A 1 11  ? 101.635 121.450 129.487 1.00 49.51  ? 11  THR A OG1 1 
ATOM   78   C CG2 . THR A 1 11  ? 99.646  120.914 130.692 1.00 49.51  ? 11  THR A CG2 1 
ATOM   79   N N   . PRO A 1 12  ? 103.655 118.090 130.556 1.00 44.68  ? 12  PRO A N   1 
ATOM   80   C CA  . PRO A 1 12  ? 104.993 117.841 130.000 1.00 44.68  ? 12  PRO A CA  1 
ATOM   81   C C   . PRO A 1 12  ? 105.023 117.796 128.483 1.00 44.68  ? 12  PRO A C   1 
ATOM   82   O O   . PRO A 1 12  ? 106.053 118.141 127.891 1.00 44.68  ? 12  PRO A O   1 
ATOM   83   C CB  . PRO A 1 12  ? 105.378 116.486 130.611 1.00 44.68  ? 12  PRO A CB  1 
ATOM   84   C CG  . PRO A 1 12  ? 104.476 116.335 131.807 1.00 44.68  ? 12  PRO A CG  1 
ATOM   85   C CD  . PRO A 1 12  ? 103.190 116.962 131.377 1.00 44.68  ? 12  PRO A CD  1 
ATOM   86   N N   . VAL A 1 13  ? 103.931 117.376 127.838 1.00 40.08  ? 13  VAL A N   1 
ATOM   87   C CA  . VAL A 1 13  ? 103.919 117.266 126.380 1.00 40.08  ? 13  VAL A CA  1 
ATOM   88   C C   . VAL A 1 13  ? 104.092 118.638 125.744 1.00 40.08  ? 13  VAL A C   1 
ATOM   89   O O   . VAL A 1 13  ? 104.864 118.810 124.792 1.00 40.08  ? 13  VAL A O   1 
ATOM   90   C CB  . VAL A 1 13  ? 102.625 116.585 125.901 1.00 40.08  ? 13  VAL A CB  1 
ATOM   91   C CG1 . VAL A 1 13  ? 102.755 116.179 124.444 1.00 40.08  ? 13  VAL A CG1 1 
ATOM   92   C CG2 . VAL A 1 13  ? 102.303 115.383 126.772 1.00 40.08  ? 13  VAL A CG2 1 
ATOM   93   N N   . PHE A 1 14  ? 103.373 119.636 126.265 1.00 38.39  ? 14  PHE A N   1 
ATOM   94   C CA  . PHE A 1 14  ? 103.487 120.991 125.738 1.00 38.39  ? 14  PHE A CA  1 
ATOM   95   C C   . PHE A 1 14  ? 104.900 121.530 125.905 1.00 38.39  ? 14  PHE A C   1 
ATOM   96   O O   . PHE A 1 14  ? 105.448 122.139 124.983 1.00 38.39  ? 14  PHE A O   1 
ATOM   97   C CB  . PHE A 1 14  ? 102.479 121.908 126.428 1.00 38.39  ? 14  PHE A CB  1 
ATOM   98   C CG  . PHE A 1 14  ? 102.556 123.338 125.983 1.00 38.39  ? 14  PHE A CG  1 
ATOM   99   C CD1 . PHE A 1 14  ? 102.210 123.700 124.694 1.00 38.39  ? 14  PHE A CD1 1 
ATOM   100  C CD2 . PHE A 1 14  ? 102.979 124.322 126.858 1.00 38.39  ? 14  PHE A CD2 1 
ATOM   101  C CE1 . PHE A 1 14  ? 102.281 125.019 124.289 1.00 38.39  ? 14  PHE A CE1 1 
ATOM   102  C CE2 . PHE A 1 14  ? 103.053 125.639 126.459 1.00 38.39  ? 14  PHE A CE2 1 
ATOM   103  C CZ  . PHE A 1 14  ? 102.704 125.988 125.173 1.00 38.39  ? 14  PHE A CZ  1 
ATOM   104  N N   . THR A 1 15  ? 105.516 121.296 127.066 1.00 35.62  ? 15  THR A N   1 
ATOM   105  C CA  . THR A 1 15  ? 106.868 121.792 127.297 1.00 35.62  ? 15  THR A CA  1 
ATOM   106  C C   . THR A 1 15  ? 107.873 121.125 126.364 1.00 35.62  ? 15  THR A C   1 
ATOM   107  O O   . THR A 1 15  ? 108.702 121.804 125.743 1.00 35.62  ? 15  THR A O   1 
ATOM   108  C CB  . THR A 1 15  ? 107.255 121.569 128.759 1.00 35.62  ? 15  THR A CB  1 
ATOM   109  O OG1 . THR A 1 15  ? 106.581 122.529 129.580 1.00 35.62  ? 15  THR A OG1 1 
ATOM   110  C CG2 . THR A 1 15  ? 108.748 121.734 128.951 1.00 35.62  ? 15  THR A CG2 1 
ATOM   111  N N   . ILE A 1 16  ? 107.791 119.799 126.225 1.00 33.91  ? 16  ILE A N   1 
ATOM   112  C CA  . ILE A 1 16  ? 108.747 119.074 125.392 1.00 33.91  ? 16  ILE A CA  1 
ATOM   113  C C   . ILE A 1 16  ? 108.591 119.459 123.926 1.00 33.91  ? 16  ILE A C   1 
ATOM   114  O O   . ILE A 1 16  ? 109.585 119.644 123.213 1.00 33.91  ? 16  ILE A O   1 
ATOM   115  C CB  . ILE A 1 16  ? 108.602 117.555 125.603 1.00 33.91  ? 16  ILE A CB  1 
ATOM   116  C CG1 . ILE A 1 16  ? 108.975 117.183 127.039 1.00 33.91  ? 16  ILE A CG1 1 
ATOM   117  C CG2 . ILE A 1 16  ? 109.467 116.787 124.618 1.00 33.91  ? 16  ILE A CG2 1 
ATOM   118  C CD1 . ILE A 1 16  ? 109.122 115.694 127.272 1.00 33.91  ? 16  ILE A CD1 1 
ATOM   119  N N   . PHE A 1 17  ? 107.356 119.600 123.448 1.00 55.03  ? 17  PHE A N   1 
ATOM   120  C CA  . PHE A 1 17  ? 107.146 119.914 122.042 1.00 55.03  ? 17  PHE A CA  1 
ATOM   121  C C   . PHE A 1 17  ? 107.108 121.412 121.758 1.00 55.03  ? 17  PHE A C   1 
ATOM   122  O O   . PHE A 1 17  ? 106.931 121.801 120.599 1.00 55.03  ? 17  PHE A O   1 
ATOM   123  C CB  . PHE A 1 17  ? 105.864 119.246 121.539 1.00 55.03  ? 17  PHE A CB  1 
ATOM   124  C CG  . PHE A 1 17  ? 106.060 117.817 121.114 1.00 55.03  ? 17  PHE A CG  1 
ATOM   125  C CD1 . PHE A 1 17  ? 106.003 116.791 122.041 1.00 55.03  ? 17  PHE A CD1 1 
ATOM   126  C CD2 . PHE A 1 17  ? 106.328 117.504 119.793 1.00 55.03  ? 17  PHE A CD2 1 
ATOM   127  C CE1 . PHE A 1 17  ? 106.192 115.478 121.655 1.00 55.03  ? 17  PHE A CE1 1 
ATOM   128  C CE2 . PHE A 1 17  ? 106.519 116.192 119.402 1.00 55.03  ? 17  PHE A CE2 1 
ATOM   129  C CZ  . PHE A 1 17  ? 106.451 115.180 120.335 1.00 55.03  ? 17  PHE A CZ  1 
ATOM   130  N N   . ILE A 1 18  ? 107.264 122.257 122.777 1.00 35.91  ? 18  ILE A N   1 
ATOM   131  C CA  . ILE A 1 18  ? 107.510 123.676 122.552 1.00 35.91  ? 18  ILE A CA  1 
ATOM   132  C C   . ILE A 1 18  ? 108.986 124.024 122.711 1.00 35.91  ? 18  ILE A C   1 
ATOM   133  O O   . ILE A 1 18  ? 109.413 125.088 122.236 1.00 35.91  ? 18  ILE A O   1 
ATOM   134  C CB  . ILE A 1 18  ? 106.645 124.550 123.486 1.00 35.91  ? 18  ILE A CB  1 
ATOM   135  C CG1 . ILE A 1 18  ? 106.301 125.874 122.807 1.00 35.91  ? 18  ILE A CG1 1 
ATOM   136  C CG2 . ILE A 1 18  ? 107.349 124.806 124.808 1.00 35.91  ? 18  ILE A CG2 1 
ATOM   137  C CD1 . ILE A 1 18  ? 105.542 125.710 121.518 1.00 35.91  ? 18  ILE A CD1 1 
ATOM   138  N N   . CYS A 1 19  ? 109.773 123.170 123.360 1.00 36.82  ? 19  CYS A N   1 
ATOM   139  C CA  . CYS A 1 19  ? 111.221 123.305 123.341 1.00 36.82  ? 19  CYS A CA  1 
ATOM   140  C C   . CYS A 1 19  ? 111.837 122.676 122.101 1.00 36.82  ? 19  CYS A C   1 
ATOM   141  O O   . CYS A 1 19  ? 113.054 122.762 121.915 1.00 36.82  ? 19  CYS A O   1 
ATOM   142  C CB  . CYS A 1 19  ? 111.831 122.682 124.600 1.00 36.82  ? 19  CYS A CB  1 
ATOM   143  N N   . LEU A 1 20  ? 111.022 122.045 121.255 1.00 31.92  ? 20  LEU A N   1 
ATOM   144  C CA  . LEU A 1 20  ? 111.484 121.438 120.016 1.00 31.92  ? 20  LEU A CA  1 
ATOM   145  C C   . LEU A 1 20  ? 111.063 122.220 118.779 1.00 31.92  ? 20  LEU A C   1 
ATOM   146  O O   . LEU A 1 20  ? 111.653 122.026 117.712 1.00 31.92  ? 20  LEU A O   1 
ATOM   147  C CB  . LEU A 1 20  ? 110.964 119.995 119.924 1.00 31.92  ? 20  LEU A CB  1 
ATOM   148  C CG  . LEU A 1 20  ? 111.585 118.981 118.962 1.00 31.92  ? 20  LEU A CG  1 
ATOM   149  C CD1 . LEU A 1 20  ? 111.543 117.603 119.592 1.00 31.92  ? 20  LEU A CD1 1 
ATOM   150  C CD2 . LEU A 1 20  ? 110.848 118.957 117.637 1.00 31.92  ? 20  LEU A CD2 1 
ATOM   151  N N   . ALA A 1 21  ? 110.081 123.112 118.900 1.00 36.15  ? 21  ALA A N   1 
ATOM   152  C CA  . ALA A 1 21  ? 109.599 123.886 117.763 1.00 36.15  ? 21  ALA A CA  1 
ATOM   153  C C   . ALA A 1 21  ? 110.456 125.120 117.509 1.00 36.15  ? 21  ALA A C   1 
ATOM   154  O O   . ALA A 1 21  ? 110.910 125.342 116.383 1.00 36.15  ? 21  ALA A O   1 
ATOM   155  C CB  . ALA A 1 21  ? 108.140 124.295 117.985 1.00 36.15  ? 21  ALA A CB  1 
ATOM   156  N N   . LEU A 1 22  ? 110.686 125.930 118.545 1.00 38.42  ? 22  LEU A N   1 
ATOM   157  C CA  . LEU A 1 22  ? 111.494 127.134 118.394 1.00 38.42  ? 22  LEU A CA  1 
ATOM   158  C C   . LEU A 1 22  ? 112.961 126.818 118.133 1.00 38.42  ? 22  LEU A C   1 
ATOM   159  O O   . LEU A 1 22  ? 113.678 127.663 117.582 1.00 38.42  ? 22  LEU A O   1 
ATOM   160  C CB  . LEU A 1 22  ? 111.364 128.003 119.645 1.00 38.42  ? 22  LEU A CB  1 
ATOM   161  C CG  . LEU A 1 22  ? 109.976 128.577 119.933 1.00 38.42  ? 22  LEU A CG  1 
ATOM   162  C CD1 . LEU A 1 22  ? 110.041 129.593 121.060 1.00 38.42  ? 22  LEU A CD1 1 
ATOM   163  C CD2 . LEU A 1 22  ? 109.371 129.197 118.684 1.00 38.42  ? 22  LEU A CD2 1 
ATOM   164  N N   . GLY A 1 23  ? 113.418 125.626 118.521 1.00 40.41  ? 23  GLY A N   1 
ATOM   165  C CA  . GLY A 1 23  ? 114.812 125.272 118.315 1.00 40.41  ? 23  GLY A CA  1 
ATOM   166  C C   . GLY A 1 23  ? 115.195 125.204 116.850 1.00 40.41  ? 23  GLY A C   1 
ATOM   167  O O   . GLY A 1 23  ? 116.275 125.652 116.462 1.00 40.41  ? 23  GLY A O   1 
ATOM   168  N N   . TYR A 1 24  ? 114.319 124.636 116.017 1.00 37.68  ? 24  TYR A N   1 
ATOM   169  C CA  . TYR A 1 24  ? 114.608 124.557 114.589 1.00 37.68  ? 24  TYR A CA  1 
ATOM   170  C C   . TYR A 1 24  ? 114.670 125.941 113.956 1.00 37.68  ? 24  TYR A C   1 
ATOM   171  O O   . TYR A 1 24  ? 115.532 126.203 113.110 1.00 37.68  ? 24  TYR A O   1 
ATOM   172  C CB  . TYR A 1 24  ? 113.568 123.686 113.886 1.00 37.68  ? 24  TYR A CB  1 
ATOM   173  C CG  . TYR A 1 24  ? 113.827 122.204 114.026 1.00 37.68  ? 24  TYR A CG  1 
ATOM   174  C CD1 . TYR A 1 24  ? 113.552 121.540 115.213 1.00 37.68  ? 24  TYR A CD1 1 
ATOM   175  C CD2 . TYR A 1 24  ? 114.353 121.470 112.974 1.00 37.68  ? 24  TYR A CD2 1 
ATOM   176  C CE1 . TYR A 1 24  ? 113.789 120.188 115.346 1.00 37.68  ? 24  TYR A CE1 1 
ATOM   177  C CE2 . TYR A 1 24  ? 114.594 120.117 113.097 1.00 37.68  ? 24  TYR A CE2 1 
ATOM   178  C CZ  . TYR A 1 24  ? 114.310 119.482 114.285 1.00 37.68  ? 24  TYR A CZ  1 
ATOM   179  O OH  . TYR A 1 24  ? 114.549 118.134 114.413 1.00 37.68  ? 24  TYR A OH  1 
ATOM   180  N N   . LEU A 1 25  ? 113.768 126.842 114.354 1.00 43.99  ? 25  LEU A N   1 
ATOM   181  C CA  . LEU A 1 25  ? 113.820 128.212 113.850 1.00 43.99  ? 25  LEU A CA  1 
ATOM   182  C C   . LEU A 1 25  ? 115.104 128.910 114.279 1.00 43.99  ? 25  LEU A C   1 
ATOM   183  O O   . LEU A 1 25  ? 115.741 129.608 113.477 1.00 43.99  ? 25  LEU A O   1 
ATOM   184  C CB  . LEU A 1 25  ? 112.601 128.996 114.331 1.00 43.99  ? 25  LEU A CB  1 
ATOM   185  C CG  . LEU A 1 25  ? 111.494 129.245 113.308 1.00 43.99  ? 25  LEU A CG  1 
ATOM   186  C CD1 . LEU A 1 25  ? 111.083 127.950 112.629 1.00 43.99  ? 25  LEU A CD1 1 
ATOM   187  C CD2 . LEU A 1 25  ? 110.304 129.910 113.974 1.00 43.99  ? 25  LEU A CD2 1 
ATOM   188  N N   . LEU A 1 26  ? 115.506 128.728 115.540 1.00 42.46  ? 26  LEU A N   1 
ATOM   189  C CA  . LEU A 1 26  ? 116.743 129.341 116.010 1.00 42.46  ? 26  LEU A CA  1 
ATOM   190  C C   . LEU A 1 26  ? 117.949 128.780 115.269 1.00 42.46  ? 26  LEU A C   1 
ATOM   191  O O   . LEU A 1 26  ? 118.892 129.515 114.957 1.00 42.46  ? 26  LEU A O   1 
ATOM   192  C CB  . LEU A 1 26  ? 116.896 129.136 117.514 1.00 42.46  ? 26  LEU A CB  1 
ATOM   193  C CG  . LEU A 1 26  ? 117.411 130.356 118.277 1.00 42.46  ? 26  LEU A CG  1 
ATOM   194  C CD1 . LEU A 1 26  ? 116.444 131.522 118.140 1.00 42.46  ? 26  LEU A CD1 1 
ATOM   195  C CD2 . LEU A 1 26  ? 117.641 130.012 119.735 1.00 42.46  ? 26  LEU A CD2 1 
ATOM   196  N N   . GLY A 1 27  ? 117.937 127.478 114.985 1.00 48.43  ? 27  GLY A N   1 
ATOM   197  C CA  . GLY A 1 27  ? 119.024 126.884 114.227 1.00 48.43  ? 27  GLY A CA  1 
ATOM   198  C C   . GLY A 1 27  ? 119.072 127.370 112.792 1.00 48.43  ? 27  GLY A C   1 
ATOM   199  O O   . GLY A 1 27  ? 120.153 127.554 112.226 1.00 48.43  ? 27  GLY A O   1 
ATOM   200  N N   . LYS A 1 28  ? 117.908 127.582 112.182 1.00 51.98  ? 28  LYS A N   1 
ATOM   201  C CA  . LYS A 1 28  ? 117.854 128.078 110.814 1.00 51.98  ? 28  LYS A CA  1 
ATOM   202  C C   . LYS A 1 28  ? 118.035 129.587 110.717 1.00 51.98  ? 28  LYS A C   1 
ATOM   203  O O   . LYS A 1 28  ? 118.110 130.110 109.600 1.00 51.98  ? 28  LYS A O   1 
ATOM   204  C CB  . LYS A 1 28  ? 116.536 127.670 110.152 1.00 51.98  ? 28  LYS A CB  1 
ATOM   205  C CG  . LYS A 1 28  ? 116.382 126.171 109.962 1.00 51.98  ? 28  LYS A CG  1 
ATOM   206  C CD  . LYS A 1 28  ? 114.966 125.814 109.550 1.00 51.98  ? 28  LYS A CD  1 
ATOM   207  C CE  . LYS A 1 28  ? 114.646 126.361 108.170 1.00 51.98  ? 28  LYS A CE  1 
ATOM   208  N NZ  . LYS A 1 28  ? 115.592 125.856 107.138 1.00 51.98  ? 28  LYS A NZ  1 
ATOM   209  N N   . LEU A 1 29  ? 118.096 130.296 111.842 1.00 61.46  ? 29  LEU A N   1 
ATOM   210  C CA  . LEU A 1 29  ? 118.433 131.713 111.802 1.00 61.46  ? 29  LEU A CA  1 
ATOM   211  C C   . LEU A 1 29  ? 119.859 131.910 111.303 1.00 61.46  ? 29  LEU A C   1 
ATOM   212  O O   . LEU A 1 29  ? 120.775 131.177 111.684 1.00 61.46  ? 29  LEU A O   1 
ATOM   213  C CB  . LEU A 1 29  ? 118.276 132.341 113.185 1.00 61.46  ? 29  LEU A CB  1 
ATOM   214  C CG  . LEU A 1 29  ? 118.169 133.866 113.198 1.00 61.46  ? 29  LEU A CG  1 
ATOM   215  C CD1 . LEU A 1 29  ? 116.929 134.323 112.448 1.00 61.46  ? 29  LEU A CD1 1 
ATOM   216  C CD2 . LEU A 1 29  ? 118.169 134.395 114.622 1.00 61.46  ? 29  LEU A CD2 1 
ATOM   217  N N   . LYS A 1 30  ? 120.045 132.912 110.443 1.00 84.55  ? 30  LYS A N   1 
ATOM   218  C CA  . LYS A 1 30  ? 121.348 133.233 109.869 1.00 84.55  ? 30  LYS A CA  1 
ATOM   219  C C   . LYS A 1 30  ? 121.926 134.444 110.593 1.00 84.55  ? 30  LYS A C   1 
ATOM   220  O O   . LYS A 1 30  ? 121.443 135.568 110.420 1.00 84.55  ? 30  LYS A O   1 
ATOM   221  C CB  . LYS A 1 30  ? 121.236 133.503 108.369 1.00 84.55  ? 30  LYS A CB  1 
ATOM   222  C CG  . LYS A 1 30  ? 121.416 132.273 107.498 1.00 84.55  ? 30  LYS A CG  1 
ATOM   223  C CD  . LYS A 1 30  ? 120.904 132.516 106.090 1.00 84.55  ? 30  LYS A CD  1 
ATOM   224  C CE  . LYS A 1 30  ? 119.632 131.734 105.818 1.00 84.55  ? 30  LYS A CE  1 
ATOM   225  N NZ  . LYS A 1 30  ? 118.754 132.431 104.837 1.00 84.55  ? 30  LYS A NZ  1 
ATOM   226  N N   . ILE A 1 31  ? 122.959 134.214 111.399 1.00 92.93  ? 31  ILE A N   1 
ATOM   227  C CA  . ILE A 1 31  ? 123.665 135.274 112.111 1.00 92.93  ? 31  ILE A CA  1 
ATOM   228  C C   . ILE A 1 31  ? 125.115 135.262 111.649 1.00 92.93  ? 31  ILE A C   1 
ATOM   229  O O   . ILE A 1 31  ? 125.803 134.242 111.780 1.00 92.93  ? 31  ILE A O   1 
ATOM   230  C CB  . ILE A 1 31  ? 123.578 135.099 113.636 1.00 92.93  ? 31  ILE A CB  1 
ATOM   231  C CG1 . ILE A 1 31  ? 122.166 134.676 114.048 1.00 92.93  ? 31  ILE A CG1 1 
ATOM   232  C CG2 . ILE A 1 31  ? 123.982 136.383 114.343 1.00 92.93  ? 31  ILE A CG2 1 
ATOM   233  C CD1 . ILE A 1 31  ? 121.986 134.524 115.541 1.00 92.93  ? 31  ILE A CD1 1 
ATOM   234  N N   . GLY A 1 32  ? 125.579 136.391 111.127 1.00 106.25 ? 32  GLY A N   1 
ATOM   235  C CA  . GLY A 1 32  ? 126.947 136.473 110.643 1.00 106.25 ? 32  GLY A CA  1 
ATOM   236  C C   . GLY A 1 32  ? 127.166 135.536 109.470 1.00 106.25 ? 32  GLY A C   1 
ATOM   237  O O   . GLY A 1 32  ? 126.467 135.602 108.452 1.00 106.25 ? 32  GLY A O   1 
ATOM   238  N N   . SER A 1 33  ? 128.150 134.647 109.605 1.00 107.53 ? 33  SER A N   1 
ATOM   239  C CA  . SER A 1 33  ? 128.461 133.663 108.575 1.00 107.53 ? 33  SER A CA  1 
ATOM   240  C C   . SER A 1 33  ? 128.263 132.230 109.053 1.00 107.53 ? 33  SER A C   1 
ATOM   241  O O   . SER A 1 33  ? 128.630 131.293 108.335 1.00 107.53 ? 33  SER A O   1 
ATOM   242  C CB  . SER A 1 33  ? 129.898 133.851 108.077 1.00 107.53 ? 33  SER A CB  1 
ATOM   243  O OG  . SER A 1 33  ? 130.834 133.445 109.060 1.00 107.53 ? 33  SER A OG  1 
ATOM   244  N N   . PHE A 1 34  ? 127.698 132.033 110.241 1.00 85.62  ? 34  PHE A N   1 
ATOM   245  C CA  . PHE A 1 34  ? 127.516 130.709 110.817 1.00 85.62  ? 34  PHE A CA  1 
ATOM   246  C C   . PHE A 1 34  ? 126.061 130.504 111.211 1.00 85.62  ? 34  PHE A C   1 
ATOM   247  O O   . PHE A 1 34  ? 125.381 131.444 111.634 1.00 85.62  ? 34  PHE A O   1 
ATOM   248  C CB  . PHE A 1 34  ? 128.431 130.509 112.033 1.00 85.62  ? 34  PHE A CB  1 
ATOM   249  C CG  . PHE A 1 34  ? 127.881 131.079 113.311 1.00 85.62  ? 34  PHE A CG  1 
ATOM   250  C CD1 . PHE A 1 34  ? 127.828 132.449 113.508 1.00 85.62  ? 34  PHE A CD1 1 
ATOM   251  C CD2 . PHE A 1 34  ? 127.425 130.245 114.318 1.00 85.62  ? 34  PHE A CD2 1 
ATOM   252  C CE1 . PHE A 1 34  ? 127.324 132.977 114.683 1.00 85.62  ? 34  PHE A CE1 1 
ATOM   253  C CE2 . PHE A 1 34  ? 126.921 130.767 115.496 1.00 85.62  ? 34  PHE A CE2 1 
ATOM   254  C CZ  . PHE A 1 34  ? 126.871 132.135 115.678 1.00 85.62  ? 34  PHE A CZ  1 
ATOM   255  N N   . THR A 1 35  ? 125.585 129.272 111.055 1.00 67.53  ? 35  THR A N   1 
ATOM   256  C CA  . THR A 1 35  ? 124.250 128.875 111.479 1.00 67.53  ? 35  THR A CA  1 
ATOM   257  C C   . THR A 1 35  ? 124.375 127.960 112.689 1.00 67.53  ? 35  THR A C   1 
ATOM   258  O O   . THR A 1 35  ? 125.183 127.026 112.681 1.00 67.53  ? 35  THR A O   1 
ATOM   259  C CB  . THR A 1 35  ? 123.497 128.169 110.349 1.00 67.53  ? 35  THR A CB  1 
ATOM   260  O OG1 . THR A 1 35  ? 124.138 126.923 110.049 1.00 67.53  ? 35  THR A OG1 1 
ATOM   261  C CG2 . THR A 1 35  ? 123.480 129.036 109.100 1.00 67.53  ? 35  THR A CG2 1 
ATOM   262  N N   . LEU A 1 36  ? 123.581 128.239 113.727 1.00 48.60  ? 36  LEU A N   1 
ATOM   263  C CA  . LEU A 1 36  ? 123.722 127.514 114.987 1.00 48.60  ? 36  LEU A CA  1 
ATOM   264  C C   . LEU A 1 36  ? 123.413 126.032 114.822 1.00 48.60  ? 36  LEU A C   1 
ATOM   265  O O   . LEU A 1 36  ? 124.118 125.179 115.373 1.00 48.60  ? 36  LEU A O   1 
ATOM   266  C CB  . LEU A 1 36  ? 122.816 128.130 116.050 1.00 48.60  ? 36  LEU A CB  1 
ATOM   267  C CG  . LEU A 1 36  ? 123.202 129.528 116.528 1.00 48.60  ? 36  LEU A CG  1 
ATOM   268  C CD1 . LEU A 1 36  ? 122.310 130.574 115.886 1.00 48.60  ? 36  LEU A CD1 1 
ATOM   269  C CD2 . LEU A 1 36  ? 123.131 129.607 118.040 1.00 48.60  ? 36  LEU A CD2 1 
ATOM   270  N N   . GLY A 1 37  ? 122.371 125.706 114.071 1.00 44.89  ? 37  GLY A N   1 
ATOM   271  C CA  . GLY A 1 37  ? 121.980 124.326 113.892 1.00 44.89  ? 37  GLY A CA  1 
ATOM   272  C C   . GLY A 1 37  ? 120.838 123.925 114.814 1.00 44.89  ? 37  GLY A C   1 
ATOM   273  O O   . GLY A 1 37  ? 120.581 124.543 115.853 1.00 44.89  ? 37  GLY A O   1 
ATOM   274  N N   . ALA A 1 38  ? 120.154 122.849 114.419 1.00 36.43  ? 38  ALA A N   1 
ATOM   275  C CA  . ALA A 1 38  ? 118.937 122.438 115.110 1.00 36.43  ? 38  ALA A CA  1 
ATOM   276  C C   . ALA A 1 38  ? 119.227 121.996 116.538 1.00 36.43  ? 38  ALA A C   1 
ATOM   277  O O   . ALA A 1 38  ? 118.538 122.413 117.474 1.00 36.43  ? 38  ALA A O   1 
ATOM   278  C CB  . ALA A 1 38  ? 118.249 121.320 114.329 1.00 36.43  ? 38  ALA A CB  1 
ATOM   279  N N   . THR A 1 39  ? 120.245 121.152 116.724 1.00 32.35  ? 39  THR A N   1 
ATOM   280  C CA  . THR A 1 39  ? 120.533 120.615 118.052 1.00 32.35  ? 39  THR A CA  1 
ATOM   281  C C   . THR A 1 39  ? 120.958 121.711 119.022 1.00 32.35  ? 39  THR A C   1 
ATOM   282  O O   . THR A 1 39  ? 120.494 121.750 120.170 1.00 32.35  ? 39  THR A O   1 
ATOM   283  C CB  . THR A 1 39  ? 121.615 119.543 117.953 1.00 32.35  ? 39  THR A CB  1 
ATOM   284  O OG1 . THR A 1 39  ? 121.255 118.596 116.940 1.00 32.35  ? 39  THR A OG1 1 
ATOM   285  C CG2 . THR A 1 39  ? 121.763 118.826 119.274 1.00 32.35  ? 39  THR A CG2 1 
ATOM   286  N N   . VAL A 1 40  ? 121.832 122.615 118.577 1.00 34.04  ? 40  VAL A N   1 
ATOM   287  C CA  . VAL A 1 40  ? 122.293 123.693 119.445 1.00 34.04  ? 40  VAL A CA  1 
ATOM   288  C C   . VAL A 1 40  ? 121.159 124.661 119.750 1.00 34.04  ? 40  VAL A C   1 
ATOM   289  O O   . VAL A 1 40  ? 121.024 125.140 120.885 1.00 34.04  ? 40  VAL A O   1 
ATOM   290  C CB  . VAL A 1 40  ? 123.500 124.403 118.810 1.00 34.04  ? 40  VAL A CB  1 
ATOM   291  C CG1 . VAL A 1 40  ? 124.045 125.467 119.745 1.00 34.04  ? 40  VAL A CG1 1 
ATOM   292  C CG2 . VAL A 1 40  ? 124.576 123.387 118.483 1.00 34.04  ? 40  VAL A CG2 1 
ATOM   293  N N   . GLY A 1 41  ? 120.321 124.962 118.754 1.00 34.80  ? 41  GLY A N   1 
ATOM   294  C CA  . GLY A 1 41  ? 119.172 125.814 119.011 1.00 34.80  ? 41  GLY A CA  1 
ATOM   295  C C   . GLY A 1 41  ? 118.205 125.204 120.008 1.00 34.80  ? 41  GLY A C   1 
ATOM   296  O O   . GLY A 1 41  ? 117.687 125.895 120.889 1.00 34.80  ? 41  GLY A O   1 
ATOM   297  N N   . VAL A 1 42  ? 117.963 123.897 119.892 1.00 31.07  ? 42  VAL A N   1 
ATOM   298  C CA  . VAL A 1 42  ? 117.089 123.206 120.835 1.00 31.07  ? 42  VAL A CA  1 
ATOM   299  C C   . VAL A 1 42  ? 117.684 123.228 122.236 1.00 31.07  ? 42  VAL A C   1 
ATOM   300  O O   . VAL A 1 42  ? 116.968 123.449 123.219 1.00 31.07  ? 42  VAL A O   1 
ATOM   301  C CB  . VAL A 1 42  ? 116.810 121.771 120.350 1.00 31.07  ? 42  VAL A CB  1 
ATOM   302  C CG1 . VAL A 1 42  ? 116.119 120.976 121.425 1.00 31.07  ? 42  VAL A CG1 1 
ATOM   303  C CG2 . VAL A 1 42  ? 115.926 121.806 119.123 1.00 31.07  ? 42  VAL A CG2 1 
ATOM   304  N N   . LEU A 1 43  ? 118.997 123.002 122.353 1.00 32.27  ? 43  LEU A N   1 
ATOM   305  C CA  . LEU A 1 43  ? 119.635 123.065 123.666 1.00 32.27  ? 43  LEU A CA  1 
ATOM   306  C C   . LEU A 1 43  ? 119.510 124.450 124.287 1.00 32.27  ? 43  LEU A C   1 
ATOM   307  O O   . LEU A 1 43  ? 119.208 124.576 125.479 1.00 32.27  ? 43  LEU A O   1 
ATOM   308  C CB  . LEU A 1 43  ? 121.103 122.665 123.563 1.00 32.27  ? 43  LEU A CB  1 
ATOM   309  C CG  . LEU A 1 43  ? 121.748 122.245 124.886 1.00 32.27  ? 43  LEU A CG  1 
ATOM   310  C CD1 . LEU A 1 43  ? 121.230 120.908 125.388 1.00 32.27  ? 43  LEU A CD1 1 
ATOM   311  C CD2 . LEU A 1 43  ? 123.257 122.216 124.735 1.00 32.27  ? 43  LEU A CD2 1 
ATOM   312  N N   . ILE A 1 44  ? 119.724 125.500 123.493 1.00 32.86  ? 44  ILE A N   1 
ATOM   313  C CA  . ILE A 1 44  ? 119.629 126.859 124.021 1.00 32.86  ? 44  ILE A CA  1 
ATOM   314  C C   . ILE A 1 44  ? 118.204 127.164 124.467 1.00 32.86  ? 44  ILE A C   1 
ATOM   315  O O   . ILE A 1 44  ? 117.981 127.700 125.562 1.00 32.86  ? 44  ILE A O   1 
ATOM   316  C CB  . ILE A 1 44  ? 120.130 127.872 122.974 1.00 32.86  ? 44  ILE A CB  1 
ATOM   317  C CG1 . ILE A 1 44  ? 121.653 127.790 122.846 1.00 32.86  ? 44  ILE A CG1 1 
ATOM   318  C CG2 . ILE A 1 44  ? 119.701 129.282 123.337 1.00 32.86  ? 44  ILE A CG2 1 
ATOM   319  C CD1 . ILE A 1 44  ? 122.178 128.293 121.523 1.00 32.86  ? 44  ILE A CD1 1 
ATOM   320  N N   . VAL A 1 45  ? 117.216 126.811 123.641 1.00 34.09  ? 45  VAL A N   1 
ATOM   321  C CA  . VAL A 1 45  ? 115.826 127.101 123.983 1.00 34.09  ? 45  VAL A CA  1 
ATOM   322  C C   . VAL A 1 45  ? 115.396 126.299 125.206 1.00 34.09  ? 45  VAL A C   1 
ATOM   323  O O   . VAL A 1 45  ? 114.689 126.813 126.081 1.00 34.09  ? 45  VAL A O   1 
ATOM   324  C CB  . VAL A 1 45  ? 114.915 126.841 122.768 1.00 34.09  ? 45  VAL A CB  1 
ATOM   325  C CG1 . VAL A 1 45  ? 113.509 126.456 123.204 1.00 34.09  ? 45  VAL A CG1 1 
ATOM   326  C CG2 . VAL A 1 45  ? 114.868 128.070 121.876 1.00 34.09  ? 45  VAL A CG2 1 
ATOM   327  N N   . ALA A 1 46  ? 115.828 125.038 125.298 1.00 33.13  ? 46  ALA A N   1 
ATOM   328  C CA  . ALA A 1 46  ? 115.514 124.224 126.467 1.00 33.13  ? 46  ALA A CA  1 
ATOM   329  C C   . ALA A 1 46  ? 116.136 124.806 127.728 1.00 33.13  ? 46  ALA A C   1 
ATOM   330  O O   . ALA A 1 46  ? 115.501 124.825 128.788 1.00 33.13  ? 46  ALA A O   1 
ATOM   331  C CB  . ALA A 1 46  ? 115.992 122.790 126.249 1.00 33.13  ? 46  ALA A CB  1 
ATOM   332  N N   . LEU A 1 47  ? 117.382 125.281 127.634 1.00 34.47  ? 47  LEU A N   1 
ATOM   333  C CA  . LEU A 1 47  ? 118.029 125.880 128.795 1.00 34.47  ? 47  LEU A CA  1 
ATOM   334  C C   . LEU A 1 47  ? 117.298 127.136 129.247 1.00 34.47  ? 47  LEU A C   1 
ATOM   335  O O   . LEU A 1 47  ? 117.134 127.367 130.450 1.00 34.47  ? 47  LEU A O   1 
ATOM   336  C CB  . LEU A 1 47  ? 119.491 126.193 128.481 1.00 34.47  ? 47  LEU A CB  1 
ATOM   337  C CG  . LEU A 1 47  ? 120.448 125.001 128.531 1.00 34.47  ? 47  LEU A CG  1 
ATOM   338  C CD1 . LEU A 1 47  ? 121.890 125.458 128.374 1.00 34.47  ? 47  LEU A CD1 1 
ATOM   339  C CD2 . LEU A 1 47  ? 120.265 124.206 129.813 1.00 34.47  ? 47  LEU A CD2 1 
ATOM   340  N N   . LEU A 1 48  ? 116.856 127.965 128.298 1.00 34.94  ? 48  LEU A N   1 
ATOM   341  C CA  . LEU A 1 48  ? 116.105 129.162 128.675 1.00 34.94  ? 48  LEU A CA  1 
ATOM   342  C C   . LEU A 1 48  ? 114.746 128.810 129.274 1.00 34.94  ? 48  LEU A C   1 
ATOM   343  O O   . LEU A 1 48  ? 114.305 129.447 130.238 1.00 34.94  ? 48  LEU A O   1 
ATOM   344  C CB  . LEU A 1 48  ? 115.940 130.094 127.475 1.00 34.94  ? 48  LEU A CB  1 
ATOM   345  C CG  . LEU A 1 48  ? 117.229 130.510 126.767 1.00 34.94  ? 48  LEU A CG  1 
ATOM   346  C CD1 . LEU A 1 48  ? 116.935 131.449 125.609 1.00 34.94  ? 48  LEU A CD1 1 
ATOM   347  C CD2 . LEU A 1 48  ? 118.196 131.147 127.752 1.00 34.94  ? 48  LEU A CD2 1 
ATOM   348  N N   . ILE A 1 49  ? 114.067 127.802 128.720 1.00 35.53  ? 49  ILE A N   1 
ATOM   349  C CA  . ILE A 1 49  ? 112.731 127.453 129.197 1.00 35.53  ? 49  ILE A CA  1 
ATOM   350  C C   . ILE A 1 49  ? 112.795 126.826 130.586 1.00 35.53  ? 49  ILE A C   1 
ATOM   351  O O   . ILE A 1 49  ? 111.960 127.120 131.452 1.00 35.53  ? 49  ILE A O   1 
ATOM   352  C CB  . ILE A 1 49  ? 112.030 126.530 128.181 1.00 35.53  ? 49  ILE A CB  1 
ATOM   353  C CG1 . ILE A 1 49  ? 111.513 127.344 126.993 1.00 35.53  ? 49  ILE A CG1 1 
ATOM   354  C CG2 . ILE A 1 49  ? 110.886 125.762 128.827 1.00 35.53  ? 49  ILE A CG2 1 
ATOM   355  C CD1 . ILE A 1 49  ? 110.707 126.536 126.000 1.00 35.53  ? 49  ILE A CD1 1 
ATOM   356  N N   . GLY A 1 50  ? 113.802 125.986 130.837 1.00 39.85  ? 50  GLY A N   1 
ATOM   357  C CA  . GLY A 1 50  ? 113.853 125.218 132.071 1.00 39.85  ? 50  GLY A CA  1 
ATOM   358  C C   . GLY A 1 50  ? 114.034 126.040 133.330 1.00 39.85  ? 50  GLY A C   1 
ATOM   359  O O   . GLY A 1 50  ? 113.854 125.508 134.431 1.00 39.85  ? 50  GLY A O   1 
ATOM   360  N N   . GLN A 1 51  ? 114.404 127.316 133.200 1.00 41.59  ? 51  GLN A N   1 
ATOM   361  C CA  . GLN A 1 51  ? 114.536 128.169 134.377 1.00 41.59  ? 51  GLN A CA  1 
ATOM   362  C C   . GLN A 1 51  ? 113.196 128.403 135.062 1.00 41.59  ? 51  GLN A C   1 
ATOM   363  O O   . GLN A 1 51  ? 113.146 128.555 136.288 1.00 41.59  ? 51  GLN A O   1 
ATOM   364  C CB  . GLN A 1 51  ? 115.169 129.506 133.992 1.00 41.59  ? 51  GLN A CB  1 
ATOM   365  C CG  . GLN A 1 51  ? 116.399 129.382 133.115 1.00 41.59  ? 51  GLN A CG  1 
ATOM   366  C CD  . GLN A 1 51  ? 117.682 129.403 133.918 1.00 41.59  ? 51  GLN A CD  1 
ATOM   367  O OE1 . GLN A 1 51  ? 117.765 128.809 134.993 1.00 41.59  ? 51  GLN A OE1 1 
ATOM   368  N NE2 . GLN A 1 51  ? 118.694 130.089 133.400 1.00 41.59  ? 51  GLN A NE2 1 
ATOM   369  N N   . LEU A 1 52  ? 112.106 128.449 134.292 1.00 43.66  ? 52  LEU A N   1 
ATOM   370  C CA  . LEU A 1 52  ? 110.801 128.761 134.865 1.00 43.66  ? 52  LEU A CA  1 
ATOM   371  C C   . LEU A 1 52  ? 110.316 127.662 135.804 1.00 43.66  ? 52  LEU A C   1 
ATOM   372  O O   . LEU A 1 52  ? 109.748 127.952 136.863 1.00 43.66  ? 52  LEU A O   1 
ATOM   373  C CB  . LEU A 1 52  ? 109.782 128.999 133.750 1.00 43.66  ? 52  LEU A CB  1 
ATOM   374  C CG  . LEU A 1 52  ? 110.158 130.010 132.665 1.00 43.66  ? 52  LEU A CG  1 
ATOM   375  C CD1 . LEU A 1 52  ? 108.980 130.262 131.739 1.00 43.66  ? 52  LEU A CD1 1 
ATOM   376  C CD2 . LEU A 1 52  ? 110.638 131.312 133.282 1.00 43.66  ? 52  LEU A CD2 1 
ATOM   377  N N   . GLY A 1 53  ? 110.530 126.401 135.440 1.00 49.25  ? 53  GLY A N   1 
ATOM   378  C CA  . GLY A 1 53  ? 109.966 125.306 136.206 1.00 49.25  ? 53  GLY A CA  1 
ATOM   379  C C   . GLY A 1 53  ? 110.967 124.384 136.873 1.00 49.25  ? 53  GLY A C   1 
ATOM   380  O O   . GLY A 1 53  ? 112.165 124.675 136.925 1.00 49.25  ? 53  GLY A O   1 
ATOM   381  N N   . VAL A 1 54  ? 110.469 123.268 137.403 1.00 51.49  ? 54  VAL A N   1 
ATOM   382  C CA  . VAL A 1 54  ? 111.282 122.296 138.124 1.00 51.49  ? 54  VAL A CA  1 
ATOM   383  C C   . VAL A 1 54  ? 111.110 120.929 137.457 1.00 51.49  ? 54  VAL A C   1 
ATOM   384  O O   . VAL A 1 54  ? 111.156 119.883 138.115 1.00 51.49  ? 54  VAL A O   1 
ATOM   385  C CB  . VAL A 1 54  ? 110.913 122.304 139.627 1.00 51.49  ? 54  VAL A CB  1 
ATOM   386  C CG1 . VAL A 1 54  ? 109.500 121.760 139.877 1.00 51.49  ? 54  VAL A CG1 1 
ATOM   387  C CG2 . VAL A 1 54  ? 111.980 121.613 140.491 1.00 51.49  ? 54  VAL A CG2 1 
ATOM   388  N N   . PHE A 1 55  ? 110.932 120.937 136.134 1.00 46.57  ? 55  PHE A N   1 
ATOM   389  C CA  . PHE A 1 55  ? 110.563 119.729 135.399 1.00 46.57  ? 55  PHE A CA  1 
ATOM   390  C C   . PHE A 1 55  ? 111.600 118.625 135.593 1.00 46.57  ? 55  PHE A C   1 
ATOM   391  O O   . PHE A 1 55  ? 112.806 118.887 135.492 1.00 46.57  ? 55  PHE A O   1 
ATOM   392  C CB  . PHE A 1 55  ? 110.429 120.024 133.906 1.00 46.57  ? 55  PHE A CB  1 
ATOM   393  C CG  . PHE A 1 55  ? 110.087 121.449 133.590 1.00 46.57  ? 55  PHE A CG  1 
ATOM   394  C CD1 . PHE A 1 55  ? 108.810 121.935 133.798 1.00 46.57  ? 55  PHE A CD1 1 
ATOM   395  C CD2 . PHE A 1 55  ? 111.047 122.299 133.071 1.00 46.57  ? 55  PHE A CD2 1 
ATOM   396  C CE1 . PHE A 1 55  ? 108.500 123.248 133.499 1.00 46.57  ? 55  PHE A CE1 1 
ATOM   397  C CE2 . PHE A 1 55  ? 110.743 123.609 132.772 1.00 46.57  ? 55  PHE A CE2 1 
ATOM   398  C CZ  . PHE A 1 55  ? 109.468 124.084 132.983 1.00 46.57  ? 55  PHE A CZ  1 
ATOM   399  N N   . PRO A 1 56  ? 111.182 117.395 135.868 1.00 45.60  ? 56  PRO A N   1 
ATOM   400  C CA  . PRO A 1 56  ? 112.121 116.274 135.955 1.00 45.60  ? 56  PRO A CA  1 
ATOM   401  C C   . PRO A 1 56  ? 112.405 115.704 134.568 1.00 45.60  ? 56  PRO A C   1 
ATOM   402  O O   . PRO A 1 56  ? 111.963 116.229 133.549 1.00 45.60  ? 56  PRO A O   1 
ATOM   403  C CB  . PRO A 1 56  ? 111.375 115.274 136.836 1.00 45.60  ? 56  PRO A CB  1 
ATOM   404  C CG  . PRO A 1 56  ? 109.942 115.505 136.495 1.00 45.60  ? 56  PRO A CG  1 
ATOM   405  C CD  . PRO A 1 56  ? 109.801 116.977 136.164 1.00 45.60  ? 56  PRO A CD  1 
ATOM   406  N N   . ARG A 1 57  ? 113.155 114.605 134.547 1.00 39.20  ? 57  ARG A N   1 
ATOM   407  C CA  . ARG A 1 57  ? 113.595 113.974 133.309 1.00 39.20  ? 57  ARG A CA  1 
ATOM   408  C C   . ARG A 1 57  ? 113.066 112.549 133.246 1.00 39.20  ? 57  ARG A C   1 
ATOM   409  O O   . ARG A 1 57  ? 113.175 111.799 134.220 1.00 39.20  ? 57  ARG A O   1 
ATOM   410  C CB  . ARG A 1 57  ? 115.123 113.988 133.213 1.00 39.20  ? 57  ARG A CB  1 
ATOM   411  C CG  . ARG A 1 57  ? 115.739 112.885 132.374 1.00 39.20  ? 57  ARG A CG  1 
ATOM   412  C CD  . ARG A 1 57  ? 117.260 112.978 132.422 1.00 39.20  ? 57  ARG A CD  1 
ATOM   413  N NE  . ARG A 1 57  ? 117.924 111.745 132.016 1.00 39.20  ? 57  ARG A NE  1 
ATOM   414  C CZ  . ARG A 1 57  ? 117.991 111.301 130.768 1.00 39.20  ? 57  ARG A CZ  1 
ATOM   415  N NH1 . ARG A 1 57  ? 117.460 111.977 129.762 1.00 39.20  ? 57  ARG A NH1 1 
ATOM   416  N NH2 . ARG A 1 57  ? 118.615 110.153 130.521 1.00 39.20  ? 57  ARG A NH2 1 
ATOM   417  N N   . ASP A 1 58  ? 112.493 112.183 132.101 1.00 41.61  ? 58  ASP A N   1 
ATOM   418  C CA  . ASP A 1 58  ? 111.948 110.849 131.881 1.00 41.61  ? 58  ASP A CA  1 
ATOM   419  C C   . ASP A 1 58  ? 112.955 110.021 131.092 1.00 41.61  ? 58  ASP A C   1 
ATOM   420  O O   . ASP A 1 58  ? 113.366 110.415 129.996 1.00 41.61  ? 58  ASP A O   1 
ATOM   421  C CB  . ASP A 1 58  ? 110.614 110.918 131.140 1.00 41.61  ? 58  ASP A CB  1 
ATOM   422  C CG  . ASP A 1 58  ? 109.911 109.579 131.089 1.00 41.61  ? 58  ASP A CG  1 
ATOM   423  O OD1 . ASP A 1 58  ? 109.510 109.074 132.159 1.00 41.61  ? 58  ASP A OD1 1 
ATOM   424  O OD2 . ASP A 1 58  ? 109.766 109.026 129.979 1.00 41.61  ? 58  ASP A OD2 1 
ATOM   425  N N   . THR A 1 59  ? 113.348 108.876 131.652 1.00 40.95  ? 59  THR A N   1 
ATOM   426  C CA  . THR A 1 59  ? 114.399 108.066 131.048 1.00 40.95  ? 59  THR A CA  1 
ATOM   427  C C   . THR A 1 59  ? 113.900 107.279 129.838 1.00 40.95  ? 59  THR A C   1 
ATOM   428  O O   . THR A 1 59  ? 114.615 107.160 128.836 1.00 40.95  ? 59  THR A O   1 
ATOM   429  C CB  . THR A 1 59  ? 114.982 107.117 132.095 1.00 40.95  ? 59  THR A CB  1 
ATOM   430  O OG1 . THR A 1 59  ? 115.202 107.834 133.315 1.00 40.95  ? 59  THR A OG1 1 
ATOM   431  C CG2 . THR A 1 59  ? 116.305 106.551 131.620 1.00 40.95  ? 59  THR A CG2 1 
ATOM   432  N N   . LEU A 1 60  ? 112.680 106.736 129.918 1.00 38.48  ? 60  LEU A N   1 
ATOM   433  C CA  . LEU A 1 60  ? 112.190 105.830 128.881 1.00 38.48  ? 60  LEU A CA  1 
ATOM   434  C C   . LEU A 1 60  ? 111.988 106.543 127.552 1.00 38.48  ? 60  LEU A C   1 
ATOM   435  O O   . LEU A 1 60  ? 112.333 106.001 126.494 1.00 38.48  ? 60  LEU A O   1 
ATOM   436  C CB  . LEU A 1 60  ? 110.883 105.179 129.328 1.00 38.48  ? 60  LEU A CB  1 
ATOM   437  C CG  . LEU A 1 60  ? 111.006 104.104 130.400 1.00 38.48  ? 60  LEU A CG  1 
ATOM   438  C CD1 . LEU A 1 60  ? 109.637 103.537 130.732 1.00 38.48  ? 60  LEU A CD1 1 
ATOM   439  C CD2 . LEU A 1 60  ? 111.948 103.014 129.927 1.00 38.48  ? 60  LEU A CD2 1 
ATOM   440  N N   . LEU A 1 61  ? 111.409 107.744 127.584 1.00 35.61  ? 61  LEU A N   1 
ATOM   441  C CA  . LEU A 1 61  ? 111.151 108.480 126.352 1.00 35.61  ? 61  LEU A CA  1 
ATOM   442  C C   . LEU A 1 61  ? 112.454 108.797 125.629 1.00 35.61  ? 61  LEU A C   1 
ATOM   443  O O   . LEU A 1 61  ? 112.573 108.603 124.411 1.00 35.61  ? 61  LEU A O   1 
ATOM   444  C CB  . LEU A 1 61  ? 110.383 109.761 126.674 1.00 35.61  ? 61  LEU A CB  1 
ATOM   445  C CG  . LEU A 1 61  ? 109.858 110.582 125.502 1.00 35.61  ? 61  LEU A CG  1 
ATOM   446  C CD1 . LEU A 1 61  ? 108.874 109.761 124.693 1.00 35.61  ? 61  LEU A CD1 1 
ATOM   447  C CD2 . LEU A 1 61  ? 109.217 111.861 126.003 1.00 35.61  ? 61  LEU A CD2 1 
ATOM   448  N N   . GLY A 1 62  ? 113.454 109.263 126.380 1.00 33.79  ? 62  GLY A N   1 
ATOM   449  C CA  . GLY A 1 62  ? 114.749 109.540 125.786 1.00 33.79  ? 62  GLY A CA  1 
ATOM   450  C C   . GLY A 1 62  ? 115.423 108.295 125.248 1.00 33.79  ? 62  GLY A C   1 
ATOM   451  O O   . GLY A 1 62  ? 116.003 108.318 124.160 1.00 33.79  ? 62  GLY A O   1 
ATOM   452  N N   . ASP A 1 63  ? 115.338 107.184 125.989 1.00 34.40  ? 63  ASP A N   1 
ATOM   453  C CA  . ASP A 1 63  ? 115.951 105.945 125.518 1.00 34.40  ? 63  ASP A CA  1 
ATOM   454  C C   . ASP A 1 63  ? 115.317 105.466 124.218 1.00 34.40  ? 63  ASP A C   1 
ATOM   455  O O   . ASP A 1 63  ? 116.026 105.069 123.287 1.00 34.40  ? 63  ASP A O   1 
ATOM   456  C CB  . ASP A 1 63  ? 115.855 104.860 126.589 1.00 34.40  ? 63  ASP A CB  1 
ATOM   457  C CG  . ASP A 1 63  ? 116.983 104.936 127.597 1.00 34.40  ? 63  ASP A CG  1 
ATOM   458  O OD1 . ASP A 1 63  ? 118.158 104.844 127.184 1.00 34.40  ? 63  ASP A OD1 1 
ATOM   459  O OD2 . ASP A 1 63  ? 116.698 105.077 128.802 1.00 34.40  ? 63  ASP A OD2 1 
ATOM   460  N N   . ILE A 1 64  ? 113.987 105.508 124.127 1.00 31.37  ? 64  ILE A N   1 
ATOM   461  C CA  . ILE A 1 64  ? 113.317 105.037 122.916 1.00 31.37  ? 64  ILE A CA  1 
ATOM   462  C C   . ILE A 1 64  ? 113.631 105.951 121.736 1.00 31.37  ? 64  ILE A C   1 
ATOM   463  O O   . ILE A 1 64  ? 113.957 105.483 120.635 1.00 31.37  ? 64  ILE A O   1 
ATOM   464  C CB  . ILE A 1 64  ? 111.801 104.911 123.149 1.00 31.37  ? 64  ILE A CB  1 
ATOM   465  C CG1 . ILE A 1 64  ? 111.517 103.867 124.228 1.00 31.37  ? 64  ILE A CG1 1 
ATOM   466  C CG2 . ILE A 1 64  ? 111.093 104.543 121.861 1.00 31.37  ? 64  ILE A CG2 1 
ATOM   467  C CD1 . ILE A 1 64  ? 110.050 103.649 124.490 1.00 31.37  ? 64  ILE A CD1 1 
ATOM   468  N N   . PHE A 1 65  ? 113.551 107.269 121.944 1.00 27.23  ? 65  PHE A N   1 
ATOM   469  C CA  . PHE A 1 65  ? 113.782 108.181 120.832 1.00 27.23  ? 65  PHE A CA  1 
ATOM   470  C C   . PHE A 1 65  ? 115.254 108.282 120.453 1.00 27.23  ? 65  PHE A C   1 
ATOM   471  O O   . PHE A 1 65  ? 115.563 108.779 119.366 1.00 27.23  ? 65  PHE A O   1 
ATOM   472  C CB  . PHE A 1 65  ? 113.210 109.559 121.155 1.00 27.23  ? 65  PHE A CB  1 
ATOM   473  C CG  . PHE A 1 65  ? 111.792 109.736 120.697 1.00 27.23  ? 65  PHE A CG  1 
ATOM   474  C CD1 . PHE A 1 65  ? 111.497 109.839 119.349 1.00 27.23  ? 65  PHE A CD1 1 
ATOM   475  C CD2 . PHE A 1 65  ? 110.753 109.777 121.609 1.00 27.23  ? 65  PHE A CD2 1 
ATOM   476  C CE1 . PHE A 1 65  ? 110.194 109.995 118.920 1.00 27.23  ? 65  PHE A CE1 1 
ATOM   477  C CE2 . PHE A 1 65  ? 109.448 109.931 121.185 1.00 27.23  ? 65  PHE A CE2 1 
ATOM   478  C CZ  . PHE A 1 65  ? 109.169 110.040 119.840 1.00 27.23  ? 65  PHE A CZ  1 
ATOM   479  N N   . PHE A 1 66  ? 116.166 107.824 121.309 1.00 29.47  ? 66  PHE A N   1 
ATOM   480  C CA  . PHE A 1 66  ? 117.562 107.713 120.908 1.00 29.47  ? 66  PHE A CA  1 
ATOM   481  C C   . PHE A 1 66  ? 117.857 106.388 120.222 1.00 29.47  ? 66  PHE A C   1 
ATOM   482  O O   . PHE A 1 66  ? 118.692 106.340 119.308 1.00 29.47  ? 66  PHE A O   1 
ATOM   483  C CB  . PHE A 1 66  ? 118.477 107.882 122.123 1.00 29.47  ? 66  PHE A CB  1 
ATOM   484  C CG  . PHE A 1 66  ? 119.913 108.114 121.768 1.00 29.47  ? 66  PHE A CG  1 
ATOM   485  C CD1 . PHE A 1 66  ? 120.311 109.311 121.199 1.00 29.47  ? 66  PHE A CD1 1 
ATOM   486  C CD2 . PHE A 1 66  ? 120.865 107.137 121.997 1.00 29.47  ? 66  PHE A CD2 1 
ATOM   487  C CE1 . PHE A 1 66  ? 121.631 109.531 120.868 1.00 29.47  ? 66  PHE A CE1 1 
ATOM   488  C CE2 . PHE A 1 66  ? 122.188 107.351 121.668 1.00 29.47  ? 66  PHE A CE2 1 
ATOM   489  C CZ  . PHE A 1 66  ? 122.571 108.549 121.102 1.00 29.47  ? 66  PHE A CZ  1 
ATOM   490  N N   . ASP A 1 67  ? 117.186 105.312 120.642 1.00 31.51  ? 67  ASP A N   1 
ATOM   491  C CA  . ASP A 1 67  ? 117.331 104.034 119.957 1.00 31.51  ? 67  ASP A CA  1 
ATOM   492  C C   . ASP A 1 67  ? 116.821 104.121 118.526 1.00 31.51  ? 67  ASP A C   1 
ATOM   493  O O   . ASP A 1 67  ? 117.417 103.540 117.611 1.00 31.51  ? 67  ASP A O   1 
ATOM   494  C CB  . ASP A 1 67  ? 116.594 102.941 120.727 1.00 31.51  ? 67  ASP A CB  1 
ATOM   495  C CG  . ASP A 1 67  ? 117.534 102.044 121.505 1.00 31.51  ? 67  ASP A CG  1 
ATOM   496  O OD1 . ASP A 1 67  ? 118.573 101.642 120.942 1.00 31.51  ? 67  ASP A OD1 1 
ATOM   497  O OD2 . ASP A 1 67  ? 117.239 101.746 122.681 1.00 31.51  ? 67  ASP A OD2 1 
ATOM   498  N N   . PHE A 1 68  ? 115.718 104.847 118.311 1.00 29.52  ? 68  PHE A N   1 
ATOM   499  C CA  . PHE A 1 68  ? 115.235 105.056 116.947 1.00 29.52  ? 68  PHE A CA  1 
ATOM   500  C C   . PHE A 1 68  ? 116.265 105.796 116.099 1.00 29.52  ? 68  PHE A C   1 
ATOM   501  O O   . PHE A 1 68  ? 116.502 105.434 114.939 1.00 29.52  ? 68  PHE A O   1 
ATOM   502  C CB  . PHE A 1 68  ? 113.912 105.821 116.964 1.00 29.52  ? 68  PHE A CB  1 
ATOM   503  C CG  . PHE A 1 68  ? 112.716 104.963 117.255 1.00 29.52  ? 68  PHE A CG  1 
ATOM   504  C CD1 . PHE A 1 68  ? 112.829 103.584 117.309 1.00 29.52  ? 68  PHE A CD1 1 
ATOM   505  C CD2 . PHE A 1 68  ? 111.476 105.536 117.473 1.00 29.52  ? 68  PHE A CD2 1 
ATOM   506  C CE1 . PHE A 1 68  ? 111.728 102.796 117.575 1.00 29.52  ? 68  PHE A CE1 1 
ATOM   507  C CE2 . PHE A 1 68  ? 110.373 104.754 117.741 1.00 29.52  ? 68  PHE A CE2 1 
ATOM   508  C CZ  . PHE A 1 68  ? 110.499 103.383 117.792 1.00 29.52  ? 68  PHE A CZ  1 
ATOM   509  N N   . PHE A 1 69  ? 116.889 106.831 116.666 1.00 30.82  ? 69  PHE A N   1 
ATOM   510  C CA  . PHE A 1 69  ? 117.919 107.584 115.953 1.00 30.82  ? 69  PHE A CA  1 
ATOM   511  C C   . PHE A 1 69  ? 119.101 106.696 115.586 1.00 30.82  ? 69  PHE A C   1 
ATOM   512  O O   . PHE A 1 69  ? 119.593 106.730 114.450 1.00 30.82  ? 69  PHE A O   1 
ATOM   513  C CB  . PHE A 1 69  ? 118.375 108.760 116.817 1.00 30.82  ? 69  PHE A CB  1 
ATOM   514  C CG  . PHE A 1 69  ? 119.738 109.289 116.467 1.00 30.82  ? 69  PHE A CG  1 
ATOM   515  C CD1 . PHE A 1 69  ? 119.958 109.961 115.281 1.00 30.82  ? 69  PHE A CD1 1 
ATOM   516  C CD2 . PHE A 1 69  ? 120.801 109.112 117.335 1.00 30.82  ? 69  PHE A CD2 1 
ATOM   517  C CE1 . PHE A 1 69  ? 121.210 110.449 114.965 1.00 30.82  ? 69  PHE A CE1 1 
ATOM   518  C CE2 . PHE A 1 69  ? 122.054 109.595 117.023 1.00 30.82  ? 69  PHE A CE2 1 
ATOM   519  C CZ  . PHE A 1 69  ? 122.259 110.264 115.837 1.00 30.82  ? 69  PHE A CZ  1 
ATOM   520  N N   . MET A 1 70  ? 119.570 105.892 116.542 1.00 32.02  ? 70  MET A N   1 
ATOM   521  C CA  . MET A 1 70  ? 120.714 105.025 116.282 1.00 32.02  ? 70  MET A CA  1 
ATOM   522  C C   . MET A 1 70  ? 120.380 103.971 115.232 1.00 32.02  ? 70  MET A C   1 
ATOM   523  O O   . MET A 1 70  ? 121.206 103.670 114.361 1.00 32.02  ? 70  MET A O   1 
ATOM   524  C CB  . MET A 1 70  ? 121.181 104.369 117.579 1.00 32.02  ? 70  MET A CB  1 
ATOM   525  C CG  . MET A 1 70  ? 122.204 105.193 118.340 1.00 32.02  ? 70  MET A CG  1 
ATOM   526  S SD  . MET A 1 70  ? 123.632 105.626 117.332 1.00 32.02  ? 70  MET A SD  1 
ATOM   527  C CE  . MET A 1 70  ? 124.705 106.358 118.563 1.00 32.02  ? 70  MET A CE  1 
ATOM   528  N N   . PHE A 1 71  ? 119.171 103.407 115.293 1.00 26.81  ? 71  PHE A N   1 
ATOM   529  C CA  . PHE A 1 71  ? 118.763 102.419 114.300 1.00 26.81  ? 71  PHE A CA  1 
ATOM   530  C C   . PHE A 1 71  ? 118.677 103.040 112.912 1.00 26.81  ? 71  PHE A C   1 
ATOM   531  O O   . PHE A 1 71  ? 119.090 102.423 111.924 1.00 26.81  ? 71  PHE A O   1 
ATOM   532  C CB  . PHE A 1 71  ? 117.427 101.794 114.711 1.00 26.81  ? 71  PHE A CB  1 
ATOM   533  C CG  . PHE A 1 71  ? 116.955 100.692 113.801 1.00 26.81  ? 71  PHE A CG  1 
ATOM   534  C CD1 . PHE A 1 71  ? 116.195 100.969 112.677 1.00 26.81  ? 71  PHE A CD1 1 
ATOM   535  C CD2 . PHE A 1 71  ? 117.273 99.374  114.077 1.00 26.81  ? 71  PHE A CD2 1 
ATOM   536  C CE1 . PHE A 1 71  ? 115.765 99.953  111.847 1.00 26.81  ? 71  PHE A CE1 1 
ATOM   537  C CE2 . PHE A 1 71  ? 116.845 98.356  113.251 1.00 26.81  ? 71  PHE A CE2 1 
ATOM   538  C CZ  . PHE A 1 71  ? 116.091 98.646  112.136 1.00 26.81  ? 71  PHE A CZ  1 
ATOM   539  N N   . ALA A 1 72  ? 118.142 104.261 112.816 1.00 33.50  ? 72  ALA A N   1 
ATOM   540  C CA  . ALA A 1 72  ? 118.064 104.931 111.521 1.00 33.50  ? 72  ALA A CA  1 
ATOM   541  C C   . ALA A 1 72  ? 119.451 105.211 110.955 1.00 33.50  ? 72  ALA A C   1 
ATOM   542  O O   . ALA A 1 72  ? 119.693 105.014 109.756 1.00 33.50  ? 72  ALA A O   1 
ATOM   543  C CB  . ALA A 1 72  ? 117.266 106.227 111.648 1.00 33.50  ? 72  ALA A CB  1 
ATOM   544  N N   . ILE A 1 73  ? 120.375 105.671 111.803 1.00 32.40  ? 73  ILE A N   1 
ATOM   545  C CA  . ILE A 1 73  ? 121.734 105.942 111.341 1.00 32.40  ? 73  ILE A CA  1 
ATOM   546  C C   . ILE A 1 73  ? 122.405 104.657 110.870 1.00 32.40  ? 73  ILE A C   1 
ATOM   547  O O   . ILE A 1 73  ? 123.063 104.632 109.820 1.00 32.40  ? 73  ILE A O   1 
ATOM   548  C CB  . ILE A 1 73  ? 122.546 106.643 112.447 1.00 32.40  ? 73  ILE A CB  1 
ATOM   549  C CG1 . ILE A 1 73  ? 122.254 108.143 112.442 1.00 32.40  ? 73  ILE A CG1 1 
ATOM   550  C CG2 . ILE A 1 73  ? 124.034 106.408 112.266 1.00 32.40  ? 73  ILE A CG2 1 
ATOM   551  C CD1 . ILE A 1 73  ? 122.782 108.860 111.221 1.00 32.40  ? 73  ILE A CD1 1 
ATOM   552  N N   . GLY A 1 74  ? 122.241 103.569 111.628 1.00 35.09  ? 74  GLY A N   1 
ATOM   553  C CA  . GLY A 1 74  ? 122.818 102.300 111.214 1.00 35.09  ? 74  GLY A CA  1 
ATOM   554  C C   . GLY A 1 74  ? 122.237 101.788 109.910 1.00 35.09  ? 74  GLY A C   1 
ATOM   555  O O   . GLY A 1 74  ? 122.962 101.266 109.059 1.00 35.09  ? 74  GLY A O   1 
ATOM   556  N N   . TYR A 1 75  ? 120.922 101.937 109.731 1.00 41.43  ? 75  TYR A N   1 
ATOM   557  C CA  . TYR A 1 75  ? 120.288 101.512 108.488 1.00 41.43  ? 75  TYR A CA  1 
ATOM   558  C C   . TYR A 1 75  ? 120.797 102.316 107.301 1.00 41.43  ? 75  TYR A C   1 
ATOM   559  O O   . TYR A 1 75  ? 121.046 101.757 106.227 1.00 41.43  ? 75  TYR A O   1 
ATOM   560  C CB  . TYR A 1 75  ? 118.771 101.637 108.603 1.00 41.43  ? 75  TYR A CB  1 
ATOM   561  C CG  . TYR A 1 75  ? 118.006 100.617 107.794 1.00 41.43  ? 75  TYR A CG  1 
ATOM   562  C CD1 . TYR A 1 75  ? 117.947 99.289  108.191 1.00 41.43  ? 75  TYR A CD1 1 
ATOM   563  C CD2 . TYR A 1 75  ? 117.346 100.983 106.631 1.00 41.43  ? 75  TYR A CD2 1 
ATOM   564  C CE1 . TYR A 1 75  ? 117.247 98.355  107.453 1.00 41.43  ? 75  TYR A CE1 1 
ATOM   565  C CE2 . TYR A 1 75  ? 116.645 100.058 105.886 1.00 41.43  ? 75  TYR A CE2 1 
ATOM   566  C CZ  . TYR A 1 75  ? 116.598 98.747  106.301 1.00 41.43  ? 75  TYR A CZ  1 
ATOM   567  O OH  . TYR A 1 75  ? 115.900 97.825  105.559 1.00 41.43  ? 75  TYR A OH  1 
ATOM   568  N N   . ARG A 1 76  ? 120.949 103.633 107.468 1.00 42.38  ? 76  ARG A N   1 
ATOM   569  C CA  . ARG A 1 76  ? 121.447 104.447 106.362 1.00 42.38  ? 76  ARG A CA  1 
ATOM   570  C C   . ARG A 1 76  ? 122.899 104.116 106.037 1.00 42.38  ? 76  ARG A C   1 
ATOM   571  O O   . ARG A 1 76  ? 123.279 104.053 104.862 1.00 42.38  ? 76  ARG A O   1 
ATOM   572  C CB  . ARG A 1 76  ? 121.296 105.934 106.679 1.00 42.38  ? 76  ARG A CB  1 
ATOM   573  C CG  . ARG A 1 76  ? 121.691 106.834 105.518 1.00 42.38  ? 76  ARG A CG  1 
ATOM   574  C CD  . ARG A 1 76  ? 121.191 108.256 105.700 1.00 42.38  ? 76  ARG A CD  1 
ATOM   575  N NE  . ARG A 1 76  ? 121.981 108.995 106.676 1.00 42.38  ? 76  ARG A NE  1 
ATOM   576  C CZ  . ARG A 1 76  ? 122.682 110.085 106.396 1.00 42.38  ? 76  ARG A CZ  1 
ATOM   577  N NH1 . ARG A 1 76  ? 122.715 110.590 105.174 1.00 42.38  ? 76  ARG A NH1 1 
ATOM   578  N NH2 . ARG A 1 76  ? 123.370 110.681 107.366 1.00 42.38  ? 76  ARG A NH2 1 
ATOM   579  N N   . VAL A 1 77  ? 123.726 103.897 107.063 1.00 43.02  ? 77  VAL A N   1 
ATOM   580  C CA  . VAL A 1 77  ? 125.139 103.611 106.841 1.00 43.02  ? 77  VAL A CA  1 
ATOM   581  C C   . VAL A 1 77  ? 125.351 102.209 106.273 1.00 43.02  ? 77  VAL A C   1 
ATOM   582  O O   . VAL A 1 77  ? 126.323 101.983 105.542 1.00 43.02  ? 77  VAL A O   1 
ATOM   583  C CB  . VAL A 1 77  ? 125.901 103.843 108.165 1.00 43.02  ? 77  VAL A CB  1 
ATOM   584  C CG1 . VAL A 1 77  ? 127.244 103.127 108.196 1.00 43.02  ? 77  VAL A CG1 1 
ATOM   585  C CG2 . VAL A 1 77  ? 126.095 105.335 108.400 1.00 43.02  ? 77  VAL A CG2 1 
ATOM   586  N N   . GLY A 1 78  ? 124.421 101.286 106.535 1.00 45.64  ? 78  GLY A N   1 
ATOM   587  C CA  . GLY A 1 78  ? 124.556 99.876  106.225 1.00 45.64  ? 78  GLY A CA  1 
ATOM   588  C C   . GLY A 1 78  ? 125.156 99.479  104.886 1.00 45.64  ? 78  GLY A C   1 
ATOM   589  O O   . GLY A 1 78  ? 126.208 98.835  104.834 1.00 45.64  ? 78  GLY A O   1 
ATOM   590  N N   . PRO A 1 79  ? 124.491 99.830  103.779 1.00 47.69  ? 79  PRO A N   1 
ATOM   591  C CA  . PRO A 1 79  ? 124.982 99.382  102.462 1.00 47.69  ? 79  PRO A CA  1 
ATOM   592  C C   . PRO A 1 79  ? 126.380 99.868  102.114 1.00 47.69  ? 79  PRO A C   1 
ATOM   593  O O   . PRO A 1 79  ? 127.116 99.155  101.421 1.00 47.69  ? 79  PRO A O   1 
ATOM   594  C CB  . PRO A 1 79  ? 123.936 99.948  101.492 1.00 47.69  ? 79  PRO A CB  1 
ATOM   595  C CG  . PRO A 1 79  ? 122.709 100.119 102.315 1.00 47.69  ? 79  PRO A CG  1 
ATOM   596  C CD  . PRO A 1 79  ? 123.194 100.520 103.674 1.00 47.69  ? 79  PRO A CD  1 
ATOM   597  N N   . SER A 1 80  ? 126.772 101.058 102.571 1.00 52.39  ? 80  SER A N   1 
ATOM   598  C CA  . SER A 1 80  ? 128.071 101.611 102.205 1.00 52.39  ? 80  SER A CA  1 
ATOM   599  C C   . SER A 1 80  ? 129.232 100.964 102.948 1.00 52.39  ? 80  SER A C   1 
ATOM   600  O O   . SER A 1 80  ? 130.367 101.028 102.462 1.00 52.39  ? 80  SER A O   1 
ATOM   601  C CB  . SER A 1 80  ? 128.089 103.120 102.456 1.00 52.39  ? 80  SER A CB  1 
ATOM   602  O OG  . SER A 1 80  ? 127.296 103.805 101.504 1.00 52.39  ? 80  SER A OG  1 
ATOM   603  N N   . PHE A 1 81  ? 128.978 100.348 104.106 1.00 47.86  ? 81  PHE A N   1 
ATOM   604  C CA  . PHE A 1 81  ? 130.067 99.844  104.940 1.00 47.86  ? 81  PHE A CA  1 
ATOM   605  C C   . PHE A 1 81  ? 130.826 98.718  104.247 1.00 47.86  ? 81  PHE A C   1 
ATOM   606  O O   . PHE A 1 81  ? 132.061 98.740  104.174 1.00 47.86  ? 81  PHE A O   1 
ATOM   607  C CB  . PHE A 1 81  ? 129.517 99.376  106.288 1.00 47.86  ? 81  PHE A CB  1 
ATOM   608  C CG  . PHE A 1 81  ? 130.554 98.773  107.192 1.00 47.86  ? 81  PHE A CG  1 
ATOM   609  C CD1 . PHE A 1 81  ? 131.718 99.460  107.489 1.00 47.86  ? 81  PHE A CD1 1 
ATOM   610  C CD2 . PHE A 1 81  ? 130.363 97.519  107.747 1.00 47.86  ? 81  PHE A CD2 1 
ATOM   611  C CE1 . PHE A 1 81  ? 132.674 98.906  108.321 1.00 47.86  ? 81  PHE A CE1 1 
ATOM   612  C CE2 . PHE A 1 81  ? 131.315 96.961  108.580 1.00 47.86  ? 81  PHE A CE2 1 
ATOM   613  C CZ  . PHE A 1 81  ? 132.471 97.655  108.867 1.00 47.86  ? 81  PHE A CZ  1 
ATOM   614  N N   . ILE A 1 82  ? 130.103 97.725  103.727 1.00 51.61  ? 82  ILE A N   1 
ATOM   615  C CA  . ILE A 1 82  ? 130.767 96.590  103.095 1.00 51.61  ? 82  ILE A CA  1 
ATOM   616  C C   . ILE A 1 82  ? 131.441 97.015  101.792 1.00 51.61  ? 82  ILE A C   1 
ATOM   617  O O   . ILE A 1 82  ? 132.522 96.521  101.452 1.00 51.61  ? 82  ILE A O   1 
ATOM   618  C CB  . ILE A 1 82  ? 129.779 95.420  102.903 1.00 51.61  ? 82  ILE A CB  1 
ATOM   619  C CG1 . ILE A 1 82  ? 130.538 94.095  102.802 1.00 51.61  ? 82  ILE A CG1 1 
ATOM   620  C CG2 . ILE A 1 82  ? 128.856 95.625  101.704 1.00 51.61  ? 82  ILE A CG2 1 
ATOM   621  C CD1 . ILE A 1 82  ? 131.094 93.610  104.123 1.00 51.61  ? 82  ILE A CD1 1 
ATOM   622  N N   . SER A 1 83  ? 130.836 97.954  101.058 1.00 54.30  ? 83  SER A N   1 
ATOM   623  C CA  . SER A 1 83  ? 131.454 98.437  99.828  1.00 54.30  ? 83  SER A CA  1 
ATOM   624  C C   . SER A 1 83  ? 132.755 99.174  100.119 1.00 54.30  ? 83  SER A C   1 
ATOM   625  O O   . SER A 1 83  ? 133.754 98.993  99.410  1.00 54.30  ? 83  SER A O   1 
ATOM   626  C CB  . SER A 1 83  ? 130.483 99.341  99.070  1.00 54.30  ? 83  SER A CB  1 
ATOM   627  O OG  . SER A 1 83  ? 131.177 100.216 98.200  1.00 54.30  ? 83  SER A OG  1 
ATOM   628  N N   . SER A 1 84  ? 132.764 100.004 101.164 1.00 52.07  ? 84  SER A N   1 
ATOM   629  C CA  . SER A 1 84  ? 133.988 100.696 101.549 1.00 52.07  ? 84  SER A CA  1 
ATOM   630  C C   . SER A 1 84  ? 135.045 99.715  102.041 1.00 52.07  ? 84  SER A C   1 
ATOM   631  O O   . SER A 1 84  ? 136.237 99.893  101.769 1.00 52.07  ? 84  SER A O   1 
ATOM   632  C CB  . SER A 1 84  ? 133.684 101.739 102.620 1.00 52.07  ? 84  SER A CB  1 
ATOM   633  O OG  . SER A 1 84  ? 134.594 102.823 102.548 1.00 52.07  ? 84  SER A OG  1 
ATOM   634  N N   . MET A 1 85  ? 134.631 98.681  102.777 1.00 54.11  ? 85  MET A N   1 
ATOM   635  C CA  . MET A 1 85  ? 135.587 97.673  103.222 1.00 54.11  ? 85  MET A CA  1 
ATOM   636  C C   . MET A 1 85  ? 136.207 96.940  102.039 1.00 54.11  ? 85  MET A C   1 
ATOM   637  O O   . MET A 1 85  ? 137.408 96.648  102.041 1.00 54.11  ? 85  MET A O   1 
ATOM   638  C CB  . MET A 1 85  ? 134.912 96.687  104.174 1.00 54.11  ? 85  MET A CB  1 
ATOM   639  C CG  . MET A 1 85  ? 134.960 97.108  105.632 1.00 54.11  ? 85  MET A CG  1 
ATOM   640  S SD  . MET A 1 85  ? 136.587 97.710  106.121 1.00 54.11  ? 85  MET A SD  1 
ATOM   641  C CE  . MET A 1 85  ? 136.470 97.599  107.905 1.00 54.11  ? 85  MET A CE  1 
ATOM   642  N N   . LYS A 1 86  ? 135.403 96.631  101.020 1.00 56.68  ? 86  LYS A N   1 
ATOM   643  C CA  . LYS A 1 86  ? 135.931 95.938  99.849  1.00 56.68  ? 86  LYS A CA  1 
ATOM   644  C C   . LYS A 1 86  ? 136.872 96.828  99.044  1.00 56.68  ? 86  LYS A C   1 
ATOM   645  O O   . LYS A 1 86  ? 137.981 96.411  98.690  1.00 56.68  ? 86  LYS A O   1 
ATOM   646  C CB  . LYS A 1 86  ? 134.788 95.439  98.966  1.00 56.68  ? 86  LYS A CB  1 
ATOM   647  C CG  . LYS A 1 86  ? 133.928 94.365  99.603  1.00 56.68  ? 86  LYS A CG  1 
ATOM   648  C CD  . LYS A 1 86  ? 132.919 93.811  98.614  1.00 56.68  ? 86  LYS A CD  1 
ATOM   649  C CE  . LYS A 1 86  ? 131.838 93.017  99.326  1.00 56.68  ? 86  LYS A CE  1 
ATOM   650  N NZ  . LYS A 1 86  ? 132.417 91.973  100.214 1.00 56.68  ? 86  LYS A NZ  1 
ATOM   651  N N   . LYS A 1 87  ? 136.452 98.057  98.742  1.00 62.75  ? 87  LYS A N   1 
ATOM   652  C CA  . LYS A 1 87  ? 137.183 98.881  97.784  1.00 62.75  ? 87  LYS A CA  1 
ATOM   653  C C   . LYS A 1 87  ? 138.146 99.864  98.443  1.00 62.75  ? 87  LYS A C   1 
ATOM   654  O O   . LYS A 1 87  ? 139.328 99.893  98.088  1.00 62.75  ? 87  LYS A O   1 
ATOM   655  C CB  . LYS A 1 87  ? 136.193 99.614  96.872  1.00 62.75  ? 87  LYS A CB  1 
ATOM   656  C CG  . LYS A 1 87  ? 135.237 98.653  96.175  1.00 62.75  ? 87  LYS A CG  1 
ATOM   657  C CD  . LYS A 1 87  ? 134.148 99.363  95.391  1.00 62.75  ? 87  LYS A CD  1 
ATOM   658  C CE  . LYS A 1 87  ? 134.739 100.400 94.458  1.00 62.75  ? 87  LYS A CE  1 
ATOM   659  N NZ  . LYS A 1 87  ? 135.430 99.766  93.300  1.00 62.75  ? 87  LYS A NZ  1 
ATOM   660  N N   . PHE A 1 88  ? 137.673 100.679 99.383  1.00 58.65  ? 88  PHE A N   1 
ATOM   661  C CA  . PHE A 1 88  ? 138.575 101.552 100.123 1.00 58.65  ? 88  PHE A CA  1 
ATOM   662  C C   . PHE A 1 88  ? 139.527 100.730 100.983 1.00 58.65  ? 88  PHE A C   1 
ATOM   663  O O   . PHE A 1 88  ? 139.177 99.654  101.475 1.00 58.65  ? 88  PHE A O   1 
ATOM   664  C CB  . PHE A 1 88  ? 137.787 102.530 100.996 1.00 58.65  ? 88  PHE A CB  1 
ATOM   665  C CG  . PHE A 1 88  ? 137.706 103.918 100.432 1.00 58.65  ? 88  PHE A CG  1 
ATOM   666  C CD1 . PHE A 1 88  ? 138.856 104.600 100.075 1.00 58.65  ? 88  PHE A CD1 1 
ATOM   667  C CD2 . PHE A 1 88  ? 136.483 104.544 100.265 1.00 58.65  ? 88  PHE A CD2 1 
ATOM   668  C CE1 . PHE A 1 88  ? 138.787 105.879 99.559  1.00 58.65  ? 88  PHE A CE1 1 
ATOM   669  C CE2 . PHE A 1 88  ? 136.408 105.822 99.748  1.00 58.65  ? 88  PHE A CE2 1 
ATOM   670  C CZ  . PHE A 1 88  ? 137.562 106.490 99.396  1.00 58.65  ? 88  PHE A CZ  1 
ATOM   671  N N   . GLY A 1 89  ? 140.743 101.239 101.154 1.00 59.30  ? 89  GLY A N   1 
ATOM   672  C CA  . GLY A 1 89  ? 141.767 100.533 101.892 1.00 59.30  ? 89  GLY A CA  1 
ATOM   673  C C   . GLY A 1 89  ? 141.578 100.610 103.397 1.00 59.30  ? 89  GLY A C   1 
ATOM   674  O O   . GLY A 1 89  ? 140.630 101.196 103.920 1.00 59.30  ? 89  GLY A O   1 
ATOM   675  N N   . ALA A 1 90  ? 142.521 99.986  104.108 1.00 61.08  ? 90  ALA A N   1 
ATOM   676  C CA  . ALA A 1 90  ? 142.515 99.969  105.566 1.00 61.08  ? 90  ALA A CA  1 
ATOM   677  C C   . ALA A 1 90  ? 142.962 101.291 106.177 1.00 61.08  ? 90  ALA A C   1 
ATOM   678  O O   . ALA A 1 90  ? 142.906 101.436 107.406 1.00 61.08  ? 90  ALA A O   1 
ATOM   679  C CB  . ALA A 1 90  ? 143.405 98.836  106.080 1.00 61.08  ? 90  ALA A CB  1 
ATOM   680  N N   . LYS A 1 91  ? 143.412 102.245 105.356 1.00 60.31  ? 91  LYS A N   1 
ATOM   681  C CA  . LYS A 1 91  ? 143.817 103.548 105.873 1.00 60.31  ? 91  LYS A CA  1 
ATOM   682  C C   . LYS A 1 91  ? 142.662 104.263 106.562 1.00 60.31  ? 91  LYS A C   1 
ATOM   683  O O   . LYS A 1 91  ? 142.886 105.057 107.485 1.00 60.31  ? 91  LYS A O   1 
ATOM   684  C CB  . LYS A 1 91  ? 144.384 104.406 104.740 1.00 60.31  ? 91  LYS A CB  1 
ATOM   685  C CG  . LYS A 1 91  ? 143.385 104.736 103.642 1.00 60.31  ? 91  LYS A CG  1 
ATOM   686  C CD  . LYS A 1 91  ? 144.004 104.587 102.262 1.00 60.31  ? 91  LYS A CD  1 
ATOM   687  C CE  . LYS A 1 91  ? 142.931 104.444 101.195 1.00 60.31  ? 91  LYS A CE  1 
ATOM   688  N NZ  . LYS A 1 91  ? 143.510 104.228 99.841  1.00 60.31  ? 91  LYS A NZ  1 
ATOM   689  N N   . ILE A 1 92  ? 141.424 103.981 106.146 1.00 53.97  ? 92  ILE A N   1 
ATOM   690  C CA  . ILE A 1 92  ? 140.261 104.563 106.807 1.00 53.97  ? 92  ILE A CA  1 
ATOM   691  C C   . ILE A 1 92  ? 140.188 104.105 108.257 1.00 53.97  ? 92  ILE A C   1 
ATOM   692  O O   . ILE A 1 92  ? 139.979 104.915 109.165 1.00 53.97  ? 92  ILE A O   1 
ATOM   693  C CB  . ILE A 1 92  ? 138.978 104.213 106.032 1.00 53.97  ? 92  ILE A CB  1 
ATOM   694  C CG1 . ILE A 1 92  ? 139.013 104.840 104.637 1.00 53.97  ? 92  ILE A CG1 1 
ATOM   695  C CG2 . ILE A 1 92  ? 137.748 104.680 106.788 1.00 53.97  ? 92  ILE A CG2 1 
ATOM   696  C CD1 . ILE A 1 92  ? 139.226 106.340 104.648 1.00 53.97  ? 92  ILE A CD1 1 
ATOM   697  N N   . VAL A 1 93  ? 140.385 102.808 108.501 1.00 52.53  ? 93  VAL A N   1 
ATOM   698  C CA  . VAL A 1 93  ? 140.384 102.294 109.867 1.00 52.53  ? 93  VAL A CA  1 
ATOM   699  C C   . VAL A 1 93  ? 141.602 102.805 110.631 1.00 52.53  ? 93  VAL A C   1 
ATOM   700  O O   . VAL A 1 93  ? 141.520 103.120 111.829 1.00 52.53  ? 93  VAL A O   1 
ATOM   701  C CB  . VAL A 1 93  ? 140.321 100.755 109.843 1.00 52.53  ? 93  VAL A CB  1 
ATOM   702  C CG1 . VAL A 1 93  ? 140.539 100.169 111.232 1.00 52.53  ? 93  VAL A CG1 1 
ATOM   703  C CG2 . VAL A 1 93  ? 138.996 100.293 109.253 1.00 52.53  ? 93  VAL A CG2 1 
ATOM   704  N N   . TYR A 1 94  ? 142.746 102.901 109.947 1.00 55.82  ? 94  TYR A N   1 
ATOM   705  C CA  . TYR A 1 94  ? 143.974 103.340 110.602 1.00 55.82  ? 94  TYR A CA  1 
ATOM   706  C C   . TYR A 1 94  ? 143.852 104.775 111.102 1.00 55.82  ? 94  TYR A C   1 
ATOM   707  O O   . TYR A 1 94  ? 144.336 105.106 112.193 1.00 55.82  ? 94  TYR A O   1 
ATOM   708  C CB  . TYR A 1 94  ? 145.146 103.207 109.633 1.00 55.82  ? 94  TYR A CB  1 
ATOM   709  C CG  . TYR A 1 94  ? 145.916 101.922 109.798 1.00 55.82  ? 94  TYR A CG  1 
ATOM   710  C CD1 . TYR A 1 94  ? 145.448 100.744 109.234 1.00 55.82  ? 94  TYR A CD1 1 
ATOM   711  C CD2 . TYR A 1 94  ? 147.098 101.879 110.522 1.00 55.82  ? 94  TYR A CD2 1 
ATOM   712  C CE1 . TYR A 1 94  ? 146.138 99.559  109.378 1.00 55.82  ? 94  TYR A CE1 1 
ATOM   713  C CE2 . TYR A 1 94  ? 147.796 100.696 110.673 1.00 55.82  ? 94  TYR A CE2 1 
ATOM   714  C CZ  . TYR A 1 94  ? 147.310 99.539  110.098 1.00 55.82  ? 94  TYR A CZ  1 
ATOM   715  O OH  . TYR A 1 94  ? 147.999 98.357  110.243 1.00 55.82  ? 94  TYR A OH  1 
ATOM   716  N N   . ALA A 1 95  ? 143.199 105.638 110.318 1.00 51.89  ? 95  ALA A N   1 
ATOM   717  C CA  . ALA A 1 95  ? 142.995 107.021 110.739 1.00 51.89  ? 95  ALA A CA  1 
ATOM   718  C C   . ALA A 1 95  ? 142.129 107.102 111.992 1.00 51.89  ? 95  ALA A C   1 
ATOM   719  O O   . ALA A 1 95  ? 142.411 107.896 112.897 1.00 51.89  ? 95  ALA A O   1 
ATOM   720  C CB  . ALA A 1 95  ? 142.370 107.830 109.604 1.00 51.89  ? 95  ALA A CB  1 
ATOM   721  N N   . THR A 1 96  ? 141.067 106.292 112.063 1.00 48.44  ? 96  THR A N   1 
ATOM   722  C CA  . THR A 1 96  ? 140.233 106.283 113.262 1.00 48.44  ? 96  THR A CA  1 
ATOM   723  C C   . THR A 1 96  ? 141.011 105.798 114.475 1.00 48.44  ? 96  THR A C   1 
ATOM   724  O O   . THR A 1 96  ? 140.865 106.349 115.572 1.00 48.44  ? 96  THR A O   1 
ATOM   725  C CB  . THR A 1 96  ? 138.998 105.408 113.063 1.00 48.44  ? 96  THR A CB  1 
ATOM   726  O OG1 . THR A 1 96  ? 139.358 104.029 113.220 1.00 48.44  ? 96  THR A OG1 1 
ATOM   727  C CG2 . THR A 1 96  ? 138.397 105.633 111.707 1.00 48.44  ? 96  THR A CG2 1 
ATOM   728  N N   . LEU A 1 97  ? 141.832 104.759 114.300 1.00 48.30  ? 97  LEU A N   1 
ATOM   729  C CA  . LEU A 1 97  ? 142.640 104.275 115.417 1.00 48.30  ? 97  LEU A CA  1 
ATOM   730  C C   . LEU A 1 97  ? 143.595 105.355 115.912 1.00 48.30  ? 97  LEU A C   1 
ATOM   731  O O   . LEU A 1 97  ? 143.741 105.563 117.126 1.00 48.30  ? 97  LEU A O   1 
ATOM   732  C CB  . LEU A 1 97  ? 143.409 103.023 115.006 1.00 48.30  ? 97  LEU A CB  1 
ATOM   733  C CG  . LEU A 1 97  ? 143.761 102.065 116.147 1.00 48.30  ? 97  LEU A CG  1 
ATOM   734  C CD1 . LEU A 1 97  ? 142.533 101.321 116.653 1.00 48.30  ? 97  LEU A CD1 1 
ATOM   735  C CD2 . LEU A 1 97  ? 144.849 101.096 115.712 1.00 48.30  ? 97  LEU A CD2 1 
ATOM   736  N N   . ILE A 1 98  ? 144.230 106.072 114.982 1.00 44.91  ? 98  ILE A N   1 
ATOM   737  C CA  . ILE A 1 98  ? 145.133 107.159 115.356 1.00 44.91  ? 98  ILE A CA  1 
ATOM   738  C C   . ILE A 1 98  ? 144.376 108.250 116.107 1.00 44.91  ? 98  ILE A C   1 
ATOM   739  O O   . ILE A 1 98  ? 144.843 108.752 117.139 1.00 44.91  ? 98  ILE A O   1 
ATOM   740  C CB  . ILE A 1 98  ? 145.843 107.709 114.104 1.00 44.91  ? 98  ILE A CB  1 
ATOM   741  C CG1 . ILE A 1 98  ? 146.985 106.779 113.692 1.00 44.91  ? 98  ILE A CG1 1 
ATOM   742  C CG2 . ILE A 1 98  ? 146.372 109.110 114.349 1.00 44.91  ? 98  ILE A CG2 1 
ATOM   743  C CD1 . ILE A 1 98  ? 147.702 107.218 112.436 1.00 44.91  ? 98  ILE A CD1 1 
ATOM   744  N N   . PHE A 1 99  ? 143.192 108.624 115.610 1.00 41.78  ? 99  PHE A N   1 
ATOM   745  C CA  . PHE A 1 99  ? 142.405 109.673 116.256 1.00 41.78  ? 99  PHE A CA  1 
ATOM   746  C C   . PHE A 1 99  ? 141.991 109.267 117.665 1.00 41.78  ? 99  PHE A C   1 
ATOM   747  O O   . PHE A 1 99  ? 142.054 110.080 118.595 1.00 41.78  ? 99  PHE A O   1 
ATOM   748  C CB  . PHE A 1 99  ? 141.182 110.009 115.394 1.00 41.78  ? 99  PHE A CB  1 
ATOM   749  C CG  . PHE A 1 99  ? 140.244 111.025 116.009 1.00 41.78  ? 99  PHE A CG  1 
ATOM   750  C CD1 . PHE A 1 99  ? 139.241 110.640 116.888 1.00 41.78  ? 99  PHE A CD1 1 
ATOM   751  C CD2 . PHE A 1 99  ? 140.370 112.369 115.703 1.00 41.78  ? 99  PHE A CD2 1 
ATOM   752  C CE1 . PHE A 1 99  ? 138.388 111.573 117.445 1.00 41.78  ? 99  PHE A CE1 1 
ATOM   753  C CE2 . PHE A 1 99  ? 139.518 113.306 116.259 1.00 41.78  ? 99  PHE A CE2 1 
ATOM   754  C CZ  . PHE A 1 99  ? 138.527 112.906 117.130 1.00 41.78  ? 99  PHE A CZ  1 
ATOM   755  N N   . LEU A 1 100 ? 141.554 108.018 117.841 1.00 43.21  ? 100 LEU A N   1 
ATOM   756  C CA  . LEU A 1 100 ? 141.141 107.563 119.165 1.00 43.21  ? 100 LEU A CA  1 
ATOM   757  C C   . LEU A 1 100 ? 142.314 107.549 120.137 1.00 43.21  ? 100 LEU A C   1 
ATOM   758  O O   . LEU A 1 100 ? 142.176 107.974 121.292 1.00 43.21  ? 100 LEU A O   1 
ATOM   759  C CB  . LEU A 1 100 ? 140.498 106.182 119.068 1.00 43.21  ? 100 LEU A CB  1 
ATOM   760  C CG  . LEU A 1 100 ? 139.221 106.138 118.227 1.00 43.21  ? 100 LEU A CG  1 
ATOM   761  C CD1 . LEU A 1 100 ? 138.561 104.785 118.324 1.00 43.21  ? 100 LEU A CD1 1 
ATOM   762  C CD2 . LEU A 1 100 ? 138.256 107.236 118.649 1.00 43.21  ? 100 LEU A CD2 1 
ATOM   763  N N   . VAL A 1 101 ? 143.481 107.081 119.684 1.00 42.40  ? 101 VAL A N   1 
ATOM   764  C CA  . VAL A 1 101 ? 144.659 107.077 120.550 1.00 42.40  ? 101 VAL A CA  1 
ATOM   765  C C   . VAL A 1 101 ? 145.033 108.502 120.947 1.00 42.40  ? 101 VAL A C   1 
ATOM   766  O O   . VAL A 1 101 ? 145.326 108.782 122.120 1.00 42.40  ? 101 VAL A O   1 
ATOM   767  C CB  . VAL A 1 101 ? 145.826 106.349 119.857 1.00 42.40  ? 101 VAL A CB  1 
ATOM   768  C CG1 . VAL A 1 101 ? 147.140 106.647 120.559 1.00 42.40  ? 101 VAL A CG1 1 
ATOM   769  C CG2 . VAL A 1 101 ? 145.567 104.853 119.824 1.00 42.40  ? 101 VAL A CG2 1 
ATOM   770  N N   . SER A 1 102 ? 145.012 109.426 119.981 1.00 43.71  ? 102 SER A N   1 
ATOM   771  C CA  . SER A 1 102 ? 145.360 110.813 120.272 1.00 43.71  ? 102 SER A CA  1 
ATOM   772  C C   . SER A 1 102 ? 144.384 111.437 121.263 1.00 43.71  ? 102 SER A C   1 
ATOM   773  O O   . SER A 1 102 ? 144.800 112.137 122.197 1.00 43.71  ? 102 SER A O   1 
ATOM   774  C CB  . SER A 1 102 ? 145.397 111.623 118.976 1.00 43.71  ? 102 SER A CB  1 
ATOM   775  O OG  . SER A 1 102 ? 145.382 113.014 119.243 1.00 43.71  ? 102 SER A OG  1 
ATOM   776  N N   . ALA A 1 103 ? 143.083 111.194 121.078 1.00 43.16  ? 103 ALA A N   1 
ATOM   777  C CA  . ALA A 1 103 ? 142.090 111.741 121.996 1.00 43.16  ? 103 ALA A CA  1 
ATOM   778  C C   . ALA A 1 103 ? 142.275 111.185 123.401 1.00 43.16  ? 103 ALA A C   1 
ATOM   779  O O   . ALA A 1 103 ? 142.191 111.929 124.386 1.00 43.16  ? 103 ALA A O   1 
ATOM   780  C CB  . ALA A 1 103 ? 140.681 111.450 121.484 1.00 43.16  ? 103 ALA A CB  1 
ATOM   781  N N   . PHE A 1 104 ? 142.541 109.879 123.509 1.00 44.41  ? 104 PHE A N   1 
ATOM   782  C CA  . PHE A 1 104 ? 142.797 109.271 124.812 1.00 44.41  ? 104 PHE A CA  1 
ATOM   783  C C   . PHE A 1 104 ? 143.982 109.929 125.508 1.00 44.41  ? 104 PHE A C   1 
ATOM   784  O O   . PHE A 1 104 ? 143.896 110.310 126.684 1.00 44.41  ? 104 PHE A O   1 
ATOM   785  C CB  . PHE A 1 104 ? 143.044 107.772 124.641 1.00 44.41  ? 104 PHE A CB  1 
ATOM   786  C CG  . PHE A 1 104 ? 143.308 107.047 125.927 1.00 44.41  ? 104 PHE A CG  1 
ATOM   787  C CD1 . PHE A 1 104 ? 142.370 107.044 126.942 1.00 44.41  ? 104 PHE A CD1 1 
ATOM   788  C CD2 . PHE A 1 104 ? 144.501 106.374 126.123 1.00 44.41  ? 104 PHE A CD2 1 
ATOM   789  C CE1 . PHE A 1 104 ? 142.613 106.378 128.128 1.00 44.41  ? 104 PHE A CE1 1 
ATOM   790  C CE2 . PHE A 1 104 ? 144.751 105.707 127.305 1.00 44.41  ? 104 PHE A CE2 1 
ATOM   791  C CZ  . PHE A 1 104 ? 143.805 105.709 128.310 1.00 44.41  ? 104 PHE A CZ  1 
ATOM   792  N N   . ILE A 1 105 ? 145.095 110.087 124.785 1.00 43.21  ? 105 ILE A N   1 
ATOM   793  C CA  . ILE A 1 105 ? 146.305 110.639 125.393 1.00 43.21  ? 105 ILE A CA  1 
ATOM   794  C C   . ILE A 1 105 ? 146.075 112.080 125.835 1.00 43.21  ? 105 ILE A C   1 
ATOM   795  O O   . ILE A 1 105 ? 146.434 112.469 126.956 1.00 43.21  ? 105 ILE A O   1 
ATOM   796  C CB  . ILE A 1 105 ? 147.496 110.526 124.425 1.00 43.21  ? 105 ILE A CB  1 
ATOM   797  C CG1 . ILE A 1 105 ? 147.820 109.057 124.151 1.00 43.21  ? 105 ILE A CG1 1 
ATOM   798  C CG2 . ILE A 1 105 ? 148.711 111.244 124.986 1.00 43.21  ? 105 ILE A CG2 1 
ATOM   799  C CD1 . ILE A 1 105 ? 149.036 108.852 123.275 1.00 43.21  ? 105 ILE A CD1 1 
ATOM   800  N N   . VAL A 1 106 ? 145.462 112.891 124.967 1.00 44.60  ? 106 VAL A N   1 
ATOM   801  C CA  . VAL A 1 106 ? 145.258 114.302 125.290 1.00 44.60  ? 106 VAL A CA  1 
ATOM   802  C C   . VAL A 1 106 ? 144.307 114.456 126.472 1.00 44.60  ? 106 VAL A C   1 
ATOM   803  O O   . VAL A 1 106 ? 144.538 115.280 127.369 1.00 44.60  ? 106 VAL A O   1 
ATOM   804  C CB  . VAL A 1 106 ? 144.760 115.069 124.051 1.00 44.60  ? 106 VAL A CB  1 
ATOM   805  C CG1 . VAL A 1 106 ? 144.390 116.492 124.421 1.00 44.60  ? 106 VAL A CG1 1 
ATOM   806  C CG2 . VAL A 1 106 ? 145.832 115.078 122.978 1.00 44.60  ? 106 VAL A CG2 1 
ATOM   807  N N   . ALA A 1 107 ? 143.224 113.671 126.498 1.00 50.84  ? 107 ALA A N   1 
ATOM   808  C CA  . ALA A 1 107 ? 142.275 113.769 127.600 1.00 50.84  ? 107 ALA A CA  1 
ATOM   809  C C   . ALA A 1 107 ? 142.911 113.355 128.919 1.00 50.84  ? 107 ALA A C   1 
ATOM   810  O O   . ALA A 1 107 ? 142.725 114.028 129.942 1.00 50.84  ? 107 ALA A O   1 
ATOM   811  C CB  . ALA A 1 107 ? 141.040 112.922 127.303 1.00 50.84  ? 107 ALA A CB  1 
ATOM   812  N N   . TYR A 1 108 ? 143.681 112.262 128.913 1.00 56.59  ? 108 TYR A N   1 
ATOM   813  C CA  . TYR A 1 108 ? 144.360 111.839 130.133 1.00 56.59  ? 108 TYR A CA  1 
ATOM   814  C C   . TYR A 1 108 ? 145.331 112.909 130.618 1.00 56.59  ? 108 TYR A C   1 
ATOM   815  O O   . TYR A 1 108 ? 145.376 113.226 131.813 1.00 56.59  ? 108 TYR A O   1 
ATOM   816  C CB  . TYR A 1 108 ? 145.087 110.515 129.901 1.00 56.59  ? 108 TYR A CB  1 
ATOM   817  C CG  . TYR A 1 108 ? 145.585 109.872 131.173 1.00 56.59  ? 108 TYR A CG  1 
ATOM   818  C CD1 . TYR A 1 108 ? 144.707 109.528 132.190 1.00 56.59  ? 108 TYR A CD1 1 
ATOM   819  C CD2 . TYR A 1 108 ? 146.936 109.614 131.358 1.00 56.59  ? 108 TYR A CD2 1 
ATOM   820  C CE1 . TYR A 1 108 ? 145.159 108.945 133.357 1.00 56.59  ? 108 TYR A CE1 1 
ATOM   821  C CE2 . TYR A 1 108 ? 147.399 109.030 132.522 1.00 56.59  ? 108 TYR A CE2 1 
ATOM   822  C CZ  . TYR A 1 108 ? 146.505 108.697 133.517 1.00 56.59  ? 108 TYR A CZ  1 
ATOM   823  O OH  . TYR A 1 108 ? 146.960 108.115 134.677 1.00 56.59  ? 108 TYR A OH  1 
ATOM   824  N N   . ALA A 1 109 ? 146.101 113.494 129.695 1.00 56.68  ? 109 ALA A N   1 
ATOM   825  C CA  . ALA A 1 109 ? 147.079 114.505 130.083 1.00 56.68  ? 109 ALA A CA  1 
ATOM   826  C C   . ALA A 1 109 ? 146.407 115.739 130.675 1.00 56.68  ? 109 ALA A C   1 
ATOM   827  O O   . ALA A 1 109 ? 146.830 116.236 131.726 1.00 56.68  ? 109 ALA A O   1 
ATOM   828  C CB  . ALA A 1 109 ? 147.940 114.888 128.881 1.00 56.68  ? 109 ALA A CB  1 
ATOM   829  N N   . CYS A 1 110 ? 145.353 116.239 130.024 1.00 59.00  ? 110 CYS A N   1 
ATOM   830  C CA  . CYS A 1 110 ? 144.681 117.435 130.526 1.00 59.00  ? 110 CYS A CA  1 
ATOM   831  C C   . CYS A 1 110 ? 144.023 117.178 131.877 1.00 59.00  ? 110 CYS A C   1 
ATOM   832  O O   . CYS A 1 110 ? 144.131 118.005 132.796 1.00 59.00  ? 110 CYS A O   1 
ATOM   833  C CB  . CYS A 1 110 ? 143.648 117.923 129.512 1.00 59.00  ? 110 CYS A CB  1 
ATOM   834  N N   . PHE A 1 111 ? 143.352 116.031 132.024 1.00 57.88  ? 111 PHE A N   1 
ATOM   835  C CA  . PHE A 1 111 ? 142.674 115.734 133.280 1.00 57.88  ? 111 PHE A CA  1 
ATOM   836  C C   . PHE A 1 111 ? 143.671 115.545 134.415 1.00 57.88  ? 111 PHE A C   1 
ATOM   837  O O   . PHE A 1 111 ? 143.418 115.982 135.543 1.00 57.88  ? 111 PHE A O   1 
ATOM   838  C CB  . PHE A 1 111 ? 141.791 114.499 133.117 1.00 57.88  ? 111 PHE A CB  1 
ATOM   839  C CG  . PHE A 1 111 ? 140.549 114.746 132.306 1.00 57.88  ? 111 PHE A CG  1 
ATOM   840  C CD1 . PHE A 1 111 ? 140.126 116.036 132.027 1.00 57.88  ? 111 PHE A CD1 1 
ATOM   841  C CD2 . PHE A 1 111 ? 139.812 113.687 131.811 1.00 57.88  ? 111 PHE A CD2 1 
ATOM   842  C CE1 . PHE A 1 111 ? 138.986 116.260 131.278 1.00 57.88  ? 111 PHE A CE1 1 
ATOM   843  C CE2 . PHE A 1 111 ? 138.676 113.905 131.058 1.00 57.88  ? 111 PHE A CE2 1 
ATOM   844  C CZ  . PHE A 1 111 ? 138.261 115.192 130.794 1.00 57.88  ? 111 PHE A CZ  1 
ATOM   845  N N   . LYS A 1 112 ? 144.813 114.910 134.141 1.00 66.79  ? 112 LYS A N   1 
ATOM   846  C CA  . LYS A 1 112 ? 145.826 114.768 135.180 1.00 66.79  ? 112 LYS A CA  1 
ATOM   847  C C   . LYS A 1 112 ? 146.449 116.113 135.537 1.00 66.79  ? 112 LYS A C   1 
ATOM   848  O O   . LYS A 1 112 ? 146.724 116.379 136.713 1.00 66.79  ? 112 LYS A O   1 
ATOM   849  C CB  . LYS A 1 112 ? 146.900 113.776 134.738 1.00 66.79  ? 112 LYS A CB  1 
ATOM   850  C CG  . LYS A 1 112 ? 147.853 113.375 135.849 1.00 66.79  ? 112 LYS A CG  1 
ATOM   851  C CD  . LYS A 1 112 ? 148.746 112.226 135.422 1.00 66.79  ? 112 LYS A CD  1 
ATOM   852  C CE  . LYS A 1 112 ? 149.687 111.819 136.542 1.00 66.79  ? 112 LYS A CE  1 
ATOM   853  N NZ  . LYS A 1 112 ? 150.530 110.655 136.158 1.00 66.79  ? 112 LYS A NZ  1 
ATOM   854  N N   . MET A 1 113 ? 146.675 116.978 134.543 1.00 68.98  ? 113 MET A N   1 
ATOM   855  C CA  . MET A 1 113 ? 147.335 118.248 134.827 1.00 68.98  ? 113 MET A CA  1 
ATOM   856  C C   . MET A 1 113 ? 146.417 119.217 135.564 1.00 68.98  ? 113 MET A C   1 
ATOM   857  O O   . MET A 1 113 ? 146.904 120.093 136.287 1.00 68.98  ? 113 MET A O   1 
ATOM   858  C CB  . MET A 1 113 ? 147.862 118.875 133.533 1.00 68.98  ? 113 MET A CB  1 
ATOM   859  C CG  . MET A 1 113 ? 146.921 119.860 132.860 1.00 68.98  ? 113 MET A CG  1 
ATOM   860  S SD  . MET A 1 113 ? 147.747 120.922 131.660 1.00 68.98  ? 113 MET A SD  1 
ATOM   861  C CE  . MET A 1 113 ? 148.450 119.698 130.557 1.00 68.98  ? 113 MET A CE  1 
ATOM   862  N N   . PHE A 1 114 ? 145.098 119.089 135.404 1.00 68.67  ? 114 PHE A N   1 
ATOM   863  C CA  . PHE A 1 114 ? 144.178 119.973 136.112 1.00 68.67  ? 114 PHE A CA  1 
ATOM   864  C C   . PHE A 1 114 ? 143.428 119.307 137.260 1.00 68.67  ? 114 PHE A C   1 
ATOM   865  O O   . PHE A 1 114 ? 142.600 119.971 137.894 1.00 68.67  ? 114 PHE A O   1 
ATOM   866  C CB  . PHE A 1 114 ? 143.179 120.603 135.133 1.00 68.67  ? 114 PHE A CB  1 
ATOM   867  C CG  . PHE A 1 114 ? 143.760 121.729 134.321 1.00 68.67  ? 114 PHE A CG  1 
ATOM   868  C CD1 . PHE A 1 114 ? 144.192 122.889 134.943 1.00 68.67  ? 114 PHE A CD1 1 
ATOM   869  C CD2 . PHE A 1 114 ? 143.875 121.630 132.946 1.00 68.67  ? 114 PHE A CD2 1 
ATOM   870  C CE1 . PHE A 1 114 ? 144.728 123.930 134.209 1.00 68.67  ? 114 PHE A CE1 1 
ATOM   871  C CE2 . PHE A 1 114 ? 144.412 122.670 132.205 1.00 68.67  ? 114 PHE A CE2 1 
ATOM   872  C CZ  . PHE A 1 114 ? 144.837 123.820 132.838 1.00 68.67  ? 114 PHE A CZ  1 
ATOM   873  N N   . HIS A 1 115 ? 143.709 118.034 137.558 1.00 70.44  ? 115 HIS A N   1 
ATOM   874  C CA  . HIS A 1 115 ? 143.074 117.309 138.666 1.00 70.44  ? 115 HIS A CA  1 
ATOM   875  C C   . HIS A 1 115 ? 141.550 117.348 138.566 1.00 70.44  ? 115 HIS A C   1 
ATOM   876  O O   . HIS A 1 115 ? 140.849 117.566 139.556 1.00 70.44  ? 115 HIS A O   1 
ATOM   877  C CB  . HIS A 1 115 ? 143.538 117.840 140.026 1.00 70.44  ? 115 HIS A CB  1 
ATOM   878  C CG  . HIS A 1 115 ? 145.016 118.055 140.121 1.00 70.44  ? 115 HIS A CG  1 
ATOM   879  N ND1 . HIS A 1 115 ? 145.576 119.297 140.330 1.00 70.44  ? 115 HIS A ND1 1 
ATOM   880  C CD2 . HIS A 1 115 ? 146.051 117.186 140.038 1.00 70.44  ? 115 HIS A CD2 1 
ATOM   881  C CE1 . HIS A 1 115 ? 146.891 119.184 140.372 1.00 70.44  ? 115 HIS A CE1 1 
ATOM   882  N NE2 . HIS A 1 115 ? 147.206 117.914 140.196 1.00 70.44  ? 115 HIS A NE2 1 
ATOM   883  N N   . ILE A 1 116 ? 141.033 117.141 137.356 1.00 62.93  ? 116 ILE A N   1 
ATOM   884  C CA  . ILE A 1 116 ? 139.594 117.193 137.131 1.00 62.93  ? 116 ILE A CA  1 
ATOM   885  C C   . ILE A 1 116 ? 138.945 115.951 137.728 1.00 62.93  ? 116 ILE A C   1 
ATOM   886  O O   . ILE A 1 116 ? 139.409 114.823 137.511 1.00 62.93  ? 116 ILE A O   1 
ATOM   887  C CB  . ILE A 1 116 ? 139.298 117.330 135.629 1.00 62.93  ? 116 ILE A CB  1 
ATOM   888  C CG1 . ILE A 1 116 ? 139.405 118.794 135.198 1.00 62.93  ? 116 ILE A CG1 1 
ATOM   889  C CG2 . ILE A 1 116 ? 137.921 116.794 135.286 1.00 62.93  ? 116 ILE A CG2 1 
ATOM   890  C CD1 . ILE A 1 116 ? 138.467 119.719 135.939 1.00 62.93  ? 116 ILE A CD1 1 
ATOM   891  N N   . GLY A 1 117 ? 137.872 116.153 138.494 1.00 58.88  ? 117 GLY A N   1 
ATOM   892  C CA  . GLY A 1 117 ? 137.161 115.066 139.127 1.00 58.88  ? 117 GLY A CA  1 
ATOM   893  C C   . GLY A 1 117 ? 136.503 114.145 138.120 1.00 58.88  ? 117 GLY A C   1 
ATOM   894  O O   . GLY A 1 117 ? 136.320 114.502 136.955 1.00 58.88  ? 117 GLY A O   1 
ATOM   895  N N   . PRO A 1 118 ? 136.172 112.921 138.543 1.00 56.16  ? 118 PRO A N   1 
ATOM   896  C CA  . PRO A 1 118 ? 135.617 111.941 137.590 1.00 56.16  ? 118 PRO A CA  1 
ATOM   897  C C   . PRO A 1 118 ? 134.300 112.351 136.945 1.00 56.16  ? 118 PRO A C   1 
ATOM   898  O O   . PRO A 1 118 ? 134.089 112.061 135.763 1.00 56.16  ? 118 PRO A O   1 
ATOM   899  C CB  . PRO A 1 118 ? 135.462 110.678 138.449 1.00 56.16  ? 118 PRO A CB  1 
ATOM   900  C CG  . PRO A 1 118 ? 135.420 111.174 139.856 1.00 56.16  ? 118 PRO A CG  1 
ATOM   901  C CD  . PRO A 1 118 ? 136.336 112.352 139.889 1.00 56.16  ? 118 PRO A CD  1 
ATOM   902  N N   . GLY A 1 119 ? 133.404 113.011 137.680 1.00 52.76  ? 119 GLY A N   1 
ATOM   903  C CA  . GLY A 1 119 ? 132.145 113.434 137.080 1.00 52.76  ? 119 GLY A CA  1 
ATOM   904  C C   . GLY A 1 119 ? 132.339 114.493 136.012 1.00 52.76  ? 119 GLY A C   1 
ATOM   905  O O   . GLY A 1 119 ? 131.754 114.420 134.924 1.00 52.76  ? 119 GLY A O   1 
ATOM   906  N N   . ILE A 1 120 ? 133.177 115.488 136.307 1.00 50.40  ? 120 ILE A N   1 
ATOM   907  C CA  . ILE A 1 120 ? 133.499 116.510 135.321 1.00 50.40  ? 120 ILE A CA  1 
ATOM   908  C C   . ILE A 1 120 ? 134.238 115.891 134.146 1.00 50.40  ? 120 ILE A C   1 
ATOM   909  O O   . ILE A 1 120 ? 134.057 116.304 132.997 1.00 50.40  ? 120 ILE A O   1 
ATOM   910  C CB  . ILE A 1 120 ? 134.317 117.637 135.976 1.00 50.40  ? 120 ILE A CB  1 
ATOM   911  C CG1 . ILE A 1 120 ? 133.598 118.154 137.222 1.00 50.40  ? 120 ILE A CG1 1 
ATOM   912  C CG2 . ILE A 1 120 ? 134.555 118.775 134.996 1.00 50.40  ? 120 ILE A CG2 1 
ATOM   913  C CD1 . ILE A 1 120 ? 134.396 119.163 138.006 1.00 50.40  ? 120 ILE A CD1 1 
ATOM   914  N N   . ALA A 1 121 ? 135.073 114.885 134.412 1.00 52.13  ? 121 ALA A N   1 
ATOM   915  C CA  . ALA A 1 121 ? 135.776 114.194 133.337 1.00 52.13  ? 121 ALA A CA  1 
ATOM   916  C C   . ALA A 1 121 ? 134.801 113.483 132.408 1.00 52.13  ? 121 ALA A C   1 
ATOM   917  O O   . ALA A 1 121 ? 134.934 113.556 131.180 1.00 52.13  ? 121 ALA A O   1 
ATOM   918  C CB  . ALA A 1 121 ? 136.778 113.202 133.925 1.00 52.13  ? 121 ALA A CB  1 
ATOM   919  N N   . ALA A 1 122 ? 133.808 112.798 132.979 1.00 44.13  ? 122 ALA A N   1 
ATOM   920  C CA  . ALA A 1 122 ? 132.797 112.133 132.163 1.00 44.13  ? 122 ALA A CA  1 
ATOM   921  C C   . ALA A 1 122 ? 132.003 113.142 131.344 1.00 44.13  ? 122 ALA A C   1 
ATOM   922  O O   . ALA A 1 122 ? 131.738 112.918 130.155 1.00 44.13  ? 122 ALA A O   1 
ATOM   923  C CB  . ALA A 1 122 ? 131.865 111.307 133.048 1.00 44.13  ? 122 ALA A CB  1 
ATOM   924  N N   . GLY A 1 123 ? 131.629 114.264 131.959 1.00 44.42  ? 123 GLY A N   1 
ATOM   925  C CA  . GLY A 1 123 ? 130.912 115.291 131.220 1.00 44.42  ? 123 GLY A CA  1 
ATOM   926  C C   . GLY A 1 123 ? 131.733 115.886 130.090 1.00 44.42  ? 123 GLY A C   1 
ATOM   927  O O   . GLY A 1 123 ? 131.227 116.096 128.984 1.00 44.42  ? 123 GLY A O   1 
ATOM   928  N N   . ILE A 1 124 ? 133.015 116.159 130.350 1.00 42.39  ? 124 ILE A N   1 
ATOM   929  C CA  . ILE A 1 124 ? 133.886 116.730 129.327 1.00 42.39  ? 124 ILE A CA  1 
ATOM   930  C C   . ILE A 1 124 ? 134.076 115.752 128.178 1.00 42.39  ? 124 ILE A C   1 
ATOM   931  O O   . ILE A 1 124 ? 134.081 116.147 127.009 1.00 42.39  ? 124 ILE A O   1 
ATOM   932  C CB  . ILE A 1 124 ? 135.231 117.163 129.942 1.00 42.39  ? 124 ILE A CB  1 
ATOM   933  C CG1 . ILE A 1 124 ? 135.034 118.375 130.853 1.00 42.39  ? 124 ILE A CG1 1 
ATOM   934  C CG2 . ILE A 1 124 ? 136.252 117.480 128.862 1.00 42.39  ? 124 ILE A CG2 1 
ATOM   935  C CD1 . ILE A 1 124 ? 134.849 119.676 130.105 1.00 42.39  ? 124 ILE A CD1 1 
ATOM   936  N N   . ILE A 1 125 ? 134.237 114.462 128.484 1.00 39.35  ? 125 ILE A N   1 
ATOM   937  C CA  . ILE A 1 125 ? 134.349 113.468 127.418 1.00 39.35  ? 125 ILE A CA  1 
ATOM   938  C C   . ILE A 1 125 ? 133.073 113.436 126.588 1.00 39.35  ? 125 ILE A C   1 
ATOM   939  O O   . ILE A 1 125 ? 133.114 113.533 125.353 1.00 39.35  ? 125 ILE A O   1 
ATOM   940  C CB  . ILE A 1 125 ? 134.669 112.084 128.010 1.00 39.35  ? 125 ILE A CB  1 
ATOM   941  C CG1 . ILE A 1 125 ? 136.099 112.047 128.546 1.00 39.35  ? 125 ILE A CG1 1 
ATOM   942  C CG2 . ILE A 1 125 ? 134.452 110.991 126.975 1.00 39.35  ? 125 ILE A CG2 1 
ATOM   943  C CD1 . ILE A 1 125 ? 137.145 112.356 127.505 1.00 39.35  ? 125 ILE A CD1 1 
ATOM   944  N N   . ALA A 1 126 ? 131.917 113.371 127.258 1.00 37.21  ? 126 ALA A N   1 
ATOM   945  C CA  . ALA A 1 126 ? 130.642 113.262 126.556 1.00 37.21  ? 126 ALA A CA  1 
ATOM   946  C C   . ALA A 1 126 ? 130.334 114.505 125.737 1.00 37.21  ? 126 ALA A C   1 
ATOM   947  O O   . ALA A 1 126 ? 129.584 114.427 124.758 1.00 37.21  ? 126 ALA A O   1 
ATOM   948  C CB  . ALA A 1 126 ? 129.514 113.000 127.552 1.00 37.21  ? 126 ALA A CB  1 
ATOM   949  N N   . GLY A 1 127 ? 130.887 115.651 126.117 1.00 39.60  ? 127 GLY A N   1 
ATOM   950  C CA  . GLY A 1 127 ? 130.653 116.857 125.351 1.00 39.60  ? 127 GLY A CA  1 
ATOM   951  C C   . GLY A 1 127 ? 131.653 117.081 124.234 1.00 39.60  ? 127 GLY A C   1 
ATOM   952  O O   . GLY A 1 127 ? 131.261 117.292 123.083 1.00 39.60  ? 127 GLY A O   1 
ATOM   953  N N   . GLY A 1 128 ? 132.946 117.056 124.563 1.00 38.26  ? 128 GLY A N   1 
ATOM   954  C CA  . GLY A 1 128 ? 133.965 117.301 123.556 1.00 38.26  ? 128 GLY A CA  1 
ATOM   955  C C   . GLY A 1 128 ? 133.976 116.240 122.477 1.00 38.26  ? 128 GLY A C   1 
ATOM   956  O O   . GLY A 1 128 ? 134.033 116.547 121.286 1.00 38.26  ? 128 GLY A O   1 
ATOM   957  N N   . LEU A 1 129 ? 133.921 114.975 122.877 1.00 39.39  ? 129 LEU A N   1 
ATOM   958  C CA  . LEU A 1 129 ? 133.741 113.890 121.923 1.00 39.39  ? 129 LEU A CA  1 
ATOM   959  C C   . LEU A 1 129 ? 132.242 113.632 121.846 1.00 39.39  ? 129 LEU A C   1 
ATOM   960  O O   . LEU A 1 129 ? 131.660 113.021 122.748 1.00 39.39  ? 129 LEU A O   1 
ATOM   961  C CB  . LEU A 1 129 ? 134.537 112.660 122.348 1.00 39.39  ? 129 LEU A CB  1 
ATOM   962  C CG  . LEU A 1 129 ? 136.033 112.927 122.568 1.00 39.39  ? 129 LEU A CG  1 
ATOM   963  C CD1 . LEU A 1 129 ? 136.809 111.632 122.664 1.00 39.39  ? 129 LEU A CD1 1 
ATOM   964  C CD2 . LEU A 1 129 ? 136.614 113.798 121.461 1.00 39.39  ? 129 LEU A CD2 1 
ATOM   965  N N   . THR A 1 130 ? 131.615 114.107 120.769 1.00 36.18  ? 130 THR A N   1 
ATOM   966  C CA  . THR A 1 130 ? 130.165 114.257 120.736 1.00 36.18  ? 130 THR A CA  1 
ATOM   967  C C   . THR A 1 130 ? 129.471 112.903 120.690 1.00 36.18  ? 130 THR A C   1 
ATOM   968  O O   . THR A 1 130 ? 129.106 112.415 119.616 1.00 36.18  ? 130 THR A O   1 
ATOM   969  C CB  . THR A 1 130 ? 129.743 115.113 119.540 1.00 36.18  ? 130 THR A CB  1 
ATOM   970  O OG1 . THR A 1 130 ? 130.640 116.221 119.406 1.00 36.18  ? 130 THR A OG1 1 
ATOM   971  C CG2 . THR A 1 130 ? 128.331 115.639 119.734 1.00 36.18  ? 130 THR A CG2 1 
ATOM   972  N N   . GLN A 1 131 ? 129.288 112.297 121.859 1.00 37.43  ? 131 GLN A N   1 
ATOM   973  C CA  . GLN A 1 131 ? 128.636 111.004 121.992 1.00 37.43  ? 131 GLN A CA  1 
ATOM   974  C C   . GLN A 1 131 ? 127.668 111.073 123.163 1.00 37.43  ? 131 GLN A C   1 
ATOM   975  O O   . GLN A 1 131 ? 128.038 111.532 124.249 1.00 37.43  ? 131 GLN A O   1 
ATOM   976  C CB  . GLN A 1 131 ? 129.668 109.891 122.200 1.00 37.43  ? 131 GLN A CB  1 
ATOM   977  C CG  . GLN A 1 131 ? 129.072 108.532 122.497 1.00 37.43  ? 131 GLN A CG  1 
ATOM   978  C CD  . GLN A 1 131 ? 128.887 107.702 121.243 1.00 37.43  ? 131 GLN A CD  1 
ATOM   979  O OE1 . GLN A 1 131 ? 128.840 108.235 120.135 1.00 37.43  ? 131 GLN A OE1 1 
ATOM   980  N NE2 . GLN A 1 131 ? 128.782 106.390 121.411 1.00 37.43  ? 131 GLN A NE2 1 
ATOM   981  N N   . SER A 1 132 ? 126.433 110.624 122.943 1.00 36.85  ? 132 SER A N   1 
ATOM   982  C CA  . SER A 1 132 ? 125.379 110.796 123.936 1.00 36.85  ? 132 SER A CA  1 
ATOM   983  C C   . SER A 1 132 ? 125.204 109.595 124.855 1.00 36.85  ? 132 SER A C   1 
ATOM   984  O O   . SER A 1 132 ? 124.713 109.757 125.978 1.00 36.85  ? 132 SER A O   1 
ATOM   985  C CB  . SER A 1 132 ? 124.052 111.104 123.240 1.00 36.85  ? 132 SER A CB  1 
ATOM   986  O OG  . SER A 1 132 ? 124.257 111.902 122.088 1.00 36.85  ? 132 SER A OG  1 
ATOM   987  N N   . ALA A 1 133 ? 125.587 108.394 124.417 1.00 35.93  ? 133 ALA A N   1 
ATOM   988  C CA  . ALA A 1 133 ? 125.467 107.214 125.267 1.00 35.93  ? 133 ALA A CA  1 
ATOM   989  C C   . ALA A 1 133 ? 126.437 107.234 126.441 1.00 35.93  ? 133 ALA A C   1 
ATOM   990  O O   . ALA A 1 133 ? 126.287 106.423 127.368 1.00 35.93  ? 133 ALA A O   1 
ATOM   991  C CB  . ALA A 1 133 ? 125.683 105.947 124.440 1.00 35.93  ? 133 ALA A CB  1 
ATOM   992  N N   . VAL A 1 134 ? 127.416 108.143 126.420 1.00 40.15  ? 134 VAL A N   1 
ATOM   993  C CA  . VAL A 1 134 ? 128.369 108.259 127.517 1.00 40.15  ? 134 VAL A CA  1 
ATOM   994  C C   . VAL A 1 134 ? 127.650 108.611 128.813 1.00 40.15  ? 134 VAL A C   1 
ATOM   995  O O   . VAL A 1 134 ? 128.024 108.134 129.887 1.00 40.15  ? 134 VAL A O   1 
ATOM   996  C CB  . VAL A 1 134 ? 129.461 109.289 127.170 1.00 40.15  ? 134 VAL A CB  1 
ATOM   997  C CG1 . VAL A 1 134 ? 130.417 109.480 128.336 1.00 40.15  ? 134 VAL A CG1 1 
ATOM   998  C CG2 . VAL A 1 134 ? 130.226 108.848 125.936 1.00 40.15  ? 134 VAL A CG2 1 
ATOM   999  N N   . ILE A 1 135 ? 126.601 109.435 128.733 1.00 45.29  ? 135 ILE A N   1 
ATOM   1000 C CA  . ILE A 1 135 ? 125.871 109.832 129.937 1.00 45.29  ? 135 ILE A CA  1 
ATOM   1001 C C   . ILE A 1 135 ? 125.267 108.614 130.626 1.00 45.29  ? 135 ILE A C   1 
ATOM   1002 O O   . ILE A 1 135 ? 125.478 108.390 131.824 1.00 45.29  ? 135 ILE A O   1 
ATOM   1003 C CB  . ILE A 1 135 ? 124.790 110.871 129.591 1.00 45.29  ? 135 ILE A CB  1 
ATOM   1004 C CG1 . ILE A 1 135 ? 125.430 112.161 129.082 1.00 45.29  ? 135 ILE A CG1 1 
ATOM   1005 C CG2 . ILE A 1 135 ? 123.906 111.149 130.794 1.00 45.29  ? 135 ILE A CG2 1 
ATOM   1006 C CD1 . ILE A 1 135 ? 124.535 112.946 128.158 1.00 45.29  ? 135 ILE A CD1 1 
ATOM   1007 N N   . GLY A 1 136 ? 124.532 107.794 129.872 1.00 50.81  ? 136 GLY A N   1 
ATOM   1008 C CA  . GLY A 1 136 ? 123.910 106.620 130.465 1.00 50.81  ? 136 GLY A CA  1 
ATOM   1009 C C   . GLY A 1 136 ? 124.918 105.590 130.936 1.00 50.81  ? 136 GLY A C   1 
ATOM   1010 O O   . GLY A 1 136 ? 124.774 105.017 132.024 1.00 50.81  ? 136 GLY A O   1 
ATOM   1011 N N   . SER A 1 137 ? 125.958 105.345 130.130 1.00 51.85  ? 137 SER A N   1 
ATOM   1012 C CA  . SER A 1 137 ? 126.969 104.367 130.521 1.00 51.85  ? 137 SER A CA  1 
ATOM   1013 C C   . SER A 1 137 ? 127.713 104.816 131.773 1.00 51.85  ? 137 SER A C   1 
ATOM   1014 O O   . SER A 1 137 ? 127.980 104.006 132.670 1.00 51.85  ? 137 SER A O   1 
ATOM   1015 C CB  . SER A 1 137 ? 127.942 104.134 129.368 1.00 51.85  ? 137 SER A CB  1 
ATOM   1016 O OG  . SER A 1 137 ? 128.981 103.253 129.751 1.00 51.85  ? 137 SER A OG  1 
ATOM   1017 N N   . SER A 1 138 ? 128.033 106.108 131.861 1.00 55.92  ? 138 SER A N   1 
ATOM   1018 C CA  . SER A 1 138 ? 128.715 106.645 133.029 1.00 55.92  ? 138 SER A CA  1 
ATOM   1019 C C   . SER A 1 138 ? 127.823 106.610 134.260 1.00 55.92  ? 138 SER A C   1 
ATOM   1020 O O   . SER A 1 138 ? 128.305 106.350 135.366 1.00 55.92  ? 138 SER A O   1 
ATOM   1021 C CB  . SER A 1 138 ? 129.178 108.071 132.740 1.00 55.92  ? 138 SER A CB  1 
ATOM   1022 O OG  . SER A 1 138 ? 128.095 108.875 132.311 1.00 55.92  ? 138 SER A OG  1 
ATOM   1023 N N   . LEU A 1 139 ? 126.524 106.881 134.097 1.00 59.20  ? 139 LEU A N   1 
ATOM   1024 C CA  . LEU A 1 139 ? 125.610 106.777 135.231 1.00 59.20  ? 139 LEU A CA  1 
ATOM   1025 C C   . LEU A 1 139 ? 125.555 105.348 135.757 1.00 59.20  ? 139 LEU A C   1 
ATOM   1026 O O   . LEU A 1 139 ? 125.610 105.120 136.973 1.00 59.20  ? 139 LEU A O   1 
ATOM   1027 C CB  . LEU A 1 139 ? 124.215 107.264 134.837 1.00 59.20  ? 139 LEU A CB  1 
ATOM   1028 C CG  . LEU A 1 139 ? 124.026 108.774 134.672 1.00 59.20  ? 139 LEU A CG  1 
ATOM   1029 C CD1 . LEU A 1 139 ? 122.552 109.124 134.541 1.00 59.20  ? 139 LEU A CD1 1 
ATOM   1030 C CD2 . LEU A 1 139 ? 124.656 109.526 135.833 1.00 59.20  ? 139 LEU A CD2 1 
ATOM   1031 N N   . GLU A 1 140 ? 125.466 104.368 134.850 1.00 69.08  ? 140 GLU A N   1 
ATOM   1032 C CA  . GLU A 1 140 ? 125.434 102.972 135.283 1.00 69.08  ? 140 GLU A CA  1 
ATOM   1033 C C   . GLU A 1 140 ? 126.741 102.572 135.966 1.00 69.08  ? 140 GLU A C   1 
ATOM   1034 O O   . GLU A 1 140 ? 126.731 101.890 137.002 1.00 69.08  ? 140 GLU A O   1 
ATOM   1035 C CB  . GLU A 1 140 ? 125.143 102.061 134.092 1.00 69.08  ? 140 GLU A CB  1 
ATOM   1036 C CG  . GLU A 1 140 ? 125.500 100.602 134.315 1.00 69.08  ? 140 GLU A CG  1 
ATOM   1037 C CD  . GLU A 1 140 ? 124.372 99.671  133.925 1.00 69.08  ? 140 GLU A CD  1 
ATOM   1038 O OE1 . GLU A 1 140 ? 123.774 99.882  132.850 1.00 69.08  ? 140 GLU A OE1 1 
ATOM   1039 O OE2 . GLU A 1 140 ? 124.077 98.732  134.694 1.00 69.08  ? 140 GLU A OE2 1 
ATOM   1040 N N   . THR A 1 141 ? 127.876 102.998 135.405 1.00 65.82  ? 141 THR A N   1 
ATOM   1041 C CA  . THR A 1 141 ? 129.171 102.672 135.996 1.00 65.82  ? 141 THR A CA  1 
ATOM   1042 C C   . THR A 1 141 ? 129.336 103.317 137.368 1.00 65.82  ? 141 THR A C   1 
ATOM   1043 O O   . THR A 1 141 ? 129.855 102.690 138.298 1.00 65.82  ? 141 THR A O   1 
ATOM   1044 C CB  . THR A 1 141 ? 130.291 103.096 135.045 1.00 65.82  ? 141 THR A CB  1 
ATOM   1045 O OG1 . THR A 1 141 ? 130.453 102.093 134.036 1.00 65.82  ? 141 THR A OG1 1 
ATOM   1046 C CG2 . THR A 1 141 ? 131.611 103.283 135.783 1.00 65.82  ? 141 THR A CG2 1 
ATOM   1047 N N   . ILE A 1 142 ? 128.895 104.569 137.513 1.00 68.94  ? 142 ILE A N   1 
ATOM   1048 C CA  . ILE A 1 142 ? 128.967 105.254 138.799 1.00 68.94  ? 142 ILE A CA  1 
ATOM   1049 C C   . ILE A 1 142 ? 128.087 104.551 139.824 1.00 68.94  ? 142 ILE A C   1 
ATOM   1050 O O   . ILE A 1 142 ? 128.469 104.397 140.992 1.00 68.94  ? 142 ILE A O   1 
ATOM   1051 C CB  . ILE A 1 142 ? 128.583 106.737 138.624 1.00 68.94  ? 142 ILE A CB  1 
ATOM   1052 C CG1 . ILE A 1 142 ? 129.819 107.564 138.267 1.00 68.94  ? 142 ILE A CG1 1 
ATOM   1053 C CG2 . ILE A 1 142 ? 127.906 107.290 139.870 1.00 68.94  ? 142 ILE A CG2 1 
ATOM   1054 C CD1 . ILE A 1 142 ? 130.724 107.848 139.443 1.00 68.94  ? 142 ILE A CD1 1 
ATOM   1055 N N   . SER A 1 143 ? 126.899 104.105 139.403 1.00 74.08  ? 143 SER A N   1 
ATOM   1056 C CA  . SER A 1 143 ? 126.027 103.361 140.307 1.00 74.08  ? 143 SER A CA  1 
ATOM   1057 C C   . SER A 1 143 ? 126.673 102.055 140.753 1.00 74.08  ? 143 SER A C   1 
ATOM   1058 O O   . SER A 1 143 ? 126.568 101.670 141.924 1.00 74.08  ? 143 SER A O   1 
ATOM   1059 C CB  . SER A 1 143 ? 124.684 103.089 139.633 1.00 74.08  ? 143 SER A CB  1 
ATOM   1060 O OG  . SER A 1 143 ? 124.815 102.106 138.621 1.00 74.08  ? 143 SER A OG  1 
ATOM   1061 N N   . LYS A 1 144 ? 127.343 101.356 139.835 1.00 75.76  ? 144 LYS A N   1 
ATOM   1062 C CA  . LYS A 1 144 ? 127.922 100.061 140.187 1.00 75.76  ? 144 LYS A CA  1 
ATOM   1063 C C   . LYS A 1 144 ? 129.177 100.205 141.045 1.00 75.76  ? 144 LYS A C   1 
ATOM   1064 O O   . LYS A 1 144 ? 129.385 99.421  141.978 1.00 75.76  ? 144 LYS A O   1 
ATOM   1065 C CB  . LYS A 1 144 ? 128.229 99.256  138.926 1.00 75.76  ? 144 LYS A CB  1 
ATOM   1066 C CG  . LYS A 1 144 ? 127.022 98.551  138.331 1.00 75.76  ? 144 LYS A CG  1 
ATOM   1067 C CD  . LYS A 1 144 ? 127.272 98.153  136.887 1.00 75.76  ? 144 LYS A CD  1 
ATOM   1068 C CE  . LYS A 1 144 ? 126.298 97.076  136.437 1.00 75.76  ? 144 LYS A CE  1 
ATOM   1069 N NZ  . LYS A 1 144 ? 124.883 97.468  136.677 1.00 75.76  ? 144 LYS A NZ  1 
ATOM   1070 N N   . LEU A 1 145 ? 130.028 101.182 140.743 1.00 80.83  ? 145 LEU A N   1 
ATOM   1071 C CA  . LEU A 1 145 ? 131.330 101.261 141.392 1.00 80.83  ? 145 LEU A CA  1 
ATOM   1072 C C   . LEU A 1 145 ? 131.172 101.658 142.860 1.00 80.83  ? 145 LEU A C   1 
ATOM   1073 O O   . LEU A 1 145 ? 130.312 102.479 143.194 1.00 80.83  ? 145 LEU A O   1 
ATOM   1074 C CB  . LEU A 1 145 ? 132.235 102.248 140.643 1.00 80.83  ? 145 LEU A CB  1 
ATOM   1075 C CG  . LEU A 1 145 ? 132.248 103.765 140.872 1.00 80.83  ? 145 LEU A CG  1 
ATOM   1076 C CD1 . LEU A 1 145 ? 133.162 104.171 142.024 1.00 80.83  ? 145 LEU A CD1 1 
ATOM   1077 C CD2 . LEU A 1 145 ? 132.640 104.490 139.597 1.00 80.83  ? 145 LEU A CD2 1 
ATOM   1078 N N   . PRO A 1 146 ? 131.982 101.088 143.762 1.00 90.01  ? 146 PRO A N   1 
ATOM   1079 C CA  . PRO A 1 146 ? 131.803 101.319 145.202 1.00 90.01  ? 146 PRO A CA  1 
ATOM   1080 C C   . PRO A 1 146 ? 132.467 102.608 145.677 1.00 90.01  ? 146 PRO A C   1 
ATOM   1081 O O   . PRO A 1 146 ? 133.694 102.730 145.679 1.00 90.01  ? 146 PRO A O   1 
ATOM   1082 C CB  . PRO A 1 146 ? 132.450 100.079 145.832 1.00 90.01  ? 146 PRO A CB  1 
ATOM   1083 C CG  . PRO A 1 146 ? 133.522 99.698  144.862 1.00 90.01  ? 146 PRO A CG  1 
ATOM   1084 C CD  . PRO A 1 146 ? 133.007 100.062 143.489 1.00 90.01  ? 146 PRO A CD  1 
ATOM   1085 N N   . ILE A 1 147 ? 131.643 103.568 146.095 1.00 95.87  ? 147 ILE A N   1 
ATOM   1086 C CA  . ILE A 1 147 ? 132.105 104.785 146.760 1.00 95.87  ? 147 ILE A CA  1 
ATOM   1087 C C   . ILE A 1 147 ? 131.068 105.199 147.795 1.00 95.87  ? 147 ILE A C   1 
ATOM   1088 O O   . ILE A 1 147 ? 130.059 104.512 147.990 1.00 95.87  ? 147 ILE A O   1 
ATOM   1089 C CB  . ILE A 1 147 ? 132.363 105.934 145.767 1.00 95.87  ? 147 ILE A CB  1 
ATOM   1090 C CG1 . ILE A 1 147 ? 131.303 105.944 144.663 1.00 95.87  ? 147 ILE A CG1 1 
ATOM   1091 C CG2 . ILE A 1 147 ? 133.782 105.874 145.211 1.00 95.87  ? 147 ILE A CG2 1 
ATOM   1092 C CD1 . ILE A 1 147 ? 131.510 107.030 143.631 1.00 95.87  ? 147 ILE A CD1 1 
ATOM   1093 N N   . SER A 1 148 ? 131.315 106.319 148.470 1.00 102.14 ? 148 SER A N   1 
ATOM   1094 C CA  . SER A 1 148 ? 130.340 106.867 149.401 1.00 102.14 ? 148 SER A CA  1 
ATOM   1095 C C   . SER A 1 148 ? 129.096 107.342 148.657 1.00 102.14 ? 148 SER A C   1 
ATOM   1096 O O   . SER A 1 148 ? 129.167 107.808 147.515 1.00 102.14 ? 148 SER A O   1 
ATOM   1097 C CB  . SER A 1 148 ? 130.948 108.021 150.198 1.00 102.14 ? 148 SER A CB  1 
ATOM   1098 O OG  . SER A 1 148 ? 129.938 108.798 150.817 1.00 102.14 ? 148 SER A OG  1 
ATOM   1099 N N   . ASP A 1 149 ? 127.947 107.228 149.330 1.00 102.80 ? 149 ASP A N   1 
ATOM   1100 C CA  . ASP A 1 149 ? 126.666 107.524 148.693 1.00 102.80 ? 149 ASP A CA  1 
ATOM   1101 C C   . ASP A 1 149 ? 126.587 108.984 148.260 1.00 102.80 ? 149 ASP A C   1 
ATOM   1102 O O   . ASP A 1 149 ? 126.093 109.285 147.166 1.00 102.80 ? 149 ASP A O   1 
ATOM   1103 C CB  . ASP A 1 149 ? 125.523 107.168 149.651 1.00 102.80 ? 149 ASP A CB  1 
ATOM   1104 C CG  . ASP A 1 149 ? 124.145 107.239 148.998 1.00 102.80 ? 149 ASP A CG  1 
ATOM   1105 O OD1 . ASP A 1 149 ? 123.771 108.291 148.439 1.00 102.80 ? 149 ASP A OD1 1 
ATOM   1106 O OD2 . ASP A 1 149 ? 123.424 106.220 149.047 1.00 102.80 ? 149 ASP A OD2 1 
ATOM   1107 N N   . HIS A 1 150 ? 127.057 109.902 149.109 1.00 98.74  ? 150 HIS A N   1 
ATOM   1108 C CA  . HIS A 1 150 ? 127.067 111.316 148.747 1.00 98.74  ? 150 HIS A CA  1 
ATOM   1109 C C   . HIS A 1 150 ? 127.916 111.557 147.506 1.00 98.74  ? 150 HIS A C   1 
ATOM   1110 O O   . HIS A 1 150 ? 127.551 112.360 146.637 1.00 98.74  ? 150 HIS A O   1 
ATOM   1111 C CB  . HIS A 1 150 ? 127.578 112.152 149.919 1.00 98.74  ? 150 HIS A CB  1 
ATOM   1112 C CG  . HIS A 1 150 ? 127.905 113.566 149.555 1.00 98.74  ? 150 HIS A CG  1 
ATOM   1113 N ND1 . HIS A 1 150 ? 126.971 114.434 149.032 1.00 98.74  ? 150 HIS A ND1 1 
ATOM   1114 C CD2 . HIS A 1 150 ? 129.063 114.262 149.634 1.00 98.74  ? 150 HIS A CD2 1 
ATOM   1115 C CE1 . HIS A 1 150 ? 127.539 115.605 148.808 1.00 98.74  ? 150 HIS A CE1 1 
ATOM   1116 N NE2 . HIS A 1 150 ? 128.809 115.528 149.164 1.00 98.74  ? 150 HIS A NE2 1 
ATOM   1117 N N   . LEU A 1 151 ? 129.054 110.865 147.409 1.00 93.93  ? 151 LEU A N   1 
ATOM   1118 C CA  . LEU A 1 151 ? 129.872 110.943 146.205 1.00 93.93  ? 151 LEU A CA  1 
ATOM   1119 C C   . LEU A 1 151 ? 129.109 110.435 144.989 1.00 93.93  ? 151 LEU A C   1 
ATOM   1120 O O   . LEU A 1 151 ? 129.204 111.019 143.903 1.00 93.93  ? 151 LEU A O   1 
ATOM   1121 C CB  . LEU A 1 151 ? 131.167 110.154 146.397 1.00 93.93  ? 151 LEU A CB  1 
ATOM   1122 C CG  . LEU A 1 151 ? 132.271 110.825 147.216 1.00 93.93  ? 151 LEU A CG  1 
ATOM   1123 C CD1 . LEU A 1 151 ? 133.589 110.086 147.045 1.00 93.93  ? 151 LEU A CD1 1 
ATOM   1124 C CD2 . LEU A 1 151 ? 132.422 112.288 146.828 1.00 93.93  ? 151 LEU A CD2 1 
ATOM   1125 N N   . LYS A 1 152 ? 128.345 109.348 145.152 1.00 86.68  ? 152 LYS A N   1 
ATOM   1126 C CA  . LYS A 1 152 ? 127.549 108.835 144.038 1.00 86.68  ? 152 LYS A CA  1 
ATOM   1127 C C   . LYS A 1 152 ? 126.533 109.867 143.560 1.00 86.68  ? 152 LYS A C   1 
ATOM   1128 O O   . LYS A 1 152 ? 126.406 110.113 142.355 1.00 86.68  ? 152 LYS A O   1 
ATOM   1129 C CB  . LYS A 1 152 ? 126.839 107.538 144.431 1.00 86.68  ? 152 LYS A CB  1 
ATOM   1130 C CG  . LYS A 1 152 ? 127.719 106.497 145.088 1.00 86.68  ? 152 LYS A CG  1 
ATOM   1131 C CD  . LYS A 1 152 ? 126.905 105.301 145.558 1.00 86.68  ? 152 LYS A CD  1 
ATOM   1132 C CE  . LYS A 1 152 ? 126.601 104.353 144.410 1.00 86.68  ? 152 LYS A CE  1 
ATOM   1133 N NZ  . LYS A 1 152 ? 127.831 103.690 143.897 1.00 86.68  ? 152 LYS A NZ  1 
ATOM   1134 N N   . THR A 1 153 ? 125.800 110.484 144.493 1.00 85.42  ? 153 THR A N   1 
ATOM   1135 C CA  . THR A 1 153 ? 124.808 111.483 144.091 1.00 85.42  ? 153 THR A CA  1 
ATOM   1136 C C   . THR A 1 153 ? 125.460 112.692 143.432 1.00 85.42  ? 153 THR A C   1 
ATOM   1137 O O   . THR A 1 153 ? 124.966 113.185 142.411 1.00 85.42  ? 153 THR A O   1 
ATOM   1138 C CB  . THR A 1 153 ? 123.941 111.935 145.272 1.00 85.42  ? 153 THR A CB  1 
ATOM   1139 O OG1 . THR A 1 153 ? 124.564 113.038 145.947 1.00 85.42  ? 153 THR A OG1 1 
ATOM   1140 C CG2 . THR A 1 153 ? 123.634 110.804 146.230 1.00 85.42  ? 153 THR A CG2 1 
ATOM   1141 N N   . LEU A 1 154 ? 126.568 113.186 143.993 1.00 79.12  ? 154 LEU A N   1 
ATOM   1142 C CA  . LEU A 1 154 ? 127.229 114.348 143.402 1.00 79.12  ? 154 LEU A CA  1 
ATOM   1143 C C   . LEU A 1 154 ? 127.747 114.041 142.000 1.00 79.12  ? 154 LEU A C   1 
ATOM   1144 O O   . LEU A 1 154 ? 127.560 114.839 141.069 1.00 79.12  ? 154 LEU A O   1 
ATOM   1145 C CB  . LEU A 1 154 ? 128.368 114.820 144.303 1.00 79.12  ? 154 LEU A CB  1 
ATOM   1146 C CG  . LEU A 1 154 ? 129.038 116.132 143.893 1.00 79.12  ? 154 LEU A CG  1 
ATOM   1147 C CD1 . LEU A 1 154 ? 128.021 117.259 143.845 1.00 79.12  ? 154 LEU A CD1 1 
ATOM   1148 C CD2 . LEU A 1 154 ? 130.176 116.475 144.840 1.00 79.12  ? 154 LEU A CD2 1 
ATOM   1149 N N   . TYR A 1 155 ? 128.389 112.882 141.828 1.00 72.72  ? 155 TYR A N   1 
ATOM   1150 C CA  . TYR A 1 155 ? 128.923 112.508 140.524 1.00 72.72  ? 155 TYR A CA  1 
ATOM   1151 C C   . TYR A 1 155 ? 127.808 112.298 139.508 1.00 72.72  ? 155 TYR A C   1 
ATOM   1152 O O   . TYR A 1 155 ? 127.945 112.688 138.344 1.00 72.72  ? 155 TYR A O   1 
ATOM   1153 C CB  . TYR A 1 155 ? 129.781 111.250 140.655 1.00 72.72  ? 155 TYR A CB  1 
ATOM   1154 C CG  . TYR A 1 155 ? 131.093 111.462 141.385 1.00 72.72  ? 155 TYR A CG  1 
ATOM   1155 C CD1 . TYR A 1 155 ? 131.512 112.734 141.756 1.00 72.72  ? 155 TYR A CD1 1 
ATOM   1156 C CD2 . TYR A 1 155 ? 131.900 110.384 141.722 1.00 72.72  ? 155 TYR A CD2 1 
ATOM   1157 C CE1 . TYR A 1 155 ? 132.704 112.927 142.426 1.00 72.72  ? 155 TYR A CE1 1 
ATOM   1158 C CE2 . TYR A 1 155 ? 133.092 110.567 142.396 1.00 72.72  ? 155 TYR A CE2 1 
ATOM   1159 C CZ  . TYR A 1 155 ? 133.490 111.840 142.743 1.00 72.72  ? 155 TYR A CZ  1 
ATOM   1160 O OH  . TYR A 1 155 ? 134.677 112.026 143.412 1.00 72.72  ? 155 TYR A OH  1 
ATOM   1161 N N   . SER A 1 156 ? 126.697 111.686 139.925 1.00 73.45  ? 156 SER A N   1 
ATOM   1162 C CA  . SER A 1 156 ? 125.582 111.481 139.008 1.00 73.45  ? 156 SER A CA  1 
ATOM   1163 C C   . SER A 1 156 ? 124.918 112.800 138.633 1.00 73.45  ? 156 SER A C   1 
ATOM   1164 O O   . SER A 1 156 ? 124.449 112.964 137.501 1.00 73.45  ? 156 SER A O   1 
ATOM   1165 C CB  . SER A 1 156 ? 124.565 110.525 139.629 1.00 73.45  ? 156 SER A CB  1 
ATOM   1166 O OG  . SER A 1 156 ? 125.209 109.390 140.180 1.00 73.45  ? 156 SER A OG  1 
ATOM   1167 N N   . ASN A 1 157 ? 124.860 113.749 139.569 1.00 70.79  ? 157 ASN A N   1 
ATOM   1168 C CA  . ASN A 1 157 ? 124.204 115.020 139.293 1.00 70.79  ? 157 ASN A CA  1 
ATOM   1169 C C   . ASN A 1 157 ? 125.055 115.942 138.429 1.00 70.79  ? 157 ASN A C   1 
ATOM   1170 O O   . ASN A 1 157 ? 124.504 116.728 137.651 1.00 70.79  ? 157 ASN A O   1 
ATOM   1171 C CB  . ASN A 1 157 ? 123.847 115.721 140.604 1.00 70.79  ? 157 ASN A CB  1 
ATOM   1172 C CG  . ASN A 1 157 ? 122.513 115.267 141.160 1.00 70.79  ? 157 ASN A CG  1 
ATOM   1173 O OD1 . ASN A 1 157 ? 122.068 114.149 140.902 1.00 70.79  ? 157 ASN A OD1 1 
ATOM   1174 N ND2 . ASN A 1 157 ? 121.865 116.136 141.927 1.00 70.79  ? 157 ASN A ND2 1 
ATOM   1175 N N   . GLN A 1 158 ? 126.383 115.871 138.548 1.00 60.11  ? 158 GLN A N   1 
ATOM   1176 C CA  . GLN A 1 158 ? 127.222 116.828 137.831 1.00 60.11  ? 158 GLN A CA  1 
ATOM   1177 C C   . GLN A 1 158 ? 127.331 116.544 136.334 1.00 60.11  ? 158 GLN A C   1 
ATOM   1178 O O   . GLN A 1 158 ? 127.750 117.434 135.587 1.00 60.11  ? 158 GLN A O   1 
ATOM   1179 C CB  . GLN A 1 158 ? 128.622 116.869 138.447 1.00 60.11  ? 158 GLN A CB  1 
ATOM   1180 C CG  . GLN A 1 158 ? 128.692 117.608 139.775 1.00 60.11  ? 158 GLN A CG  1 
ATOM   1181 C CD  . GLN A 1 158 ? 130.109 117.990 140.154 1.00 60.11  ? 158 GLN A CD  1 
ATOM   1182 O OE1 . GLN A 1 158 ? 131.059 117.690 139.433 1.00 60.11  ? 158 GLN A OE1 1 
ATOM   1183 N NE2 . GLN A 1 158 ? 130.258 118.657 141.293 1.00 60.11  ? 158 GLN A NE2 1 
ATOM   1184 N N   . ILE A 1 159 ? 126.977 115.339 135.877 1.00 51.41  ? 159 ILE A N   1 
ATOM   1185 C CA  . ILE A 1 159 ? 127.240 114.967 134.481 1.00 51.41  ? 159 ILE A CA  1 
ATOM   1186 C C   . ILE A 1 159 ? 126.435 115.780 133.469 1.00 51.41  ? 159 ILE A C   1 
ATOM   1187 O O   . ILE A 1 159 ? 127.044 116.339 132.542 1.00 51.41  ? 159 ILE A O   1 
ATOM   1188 C CB  . ILE A 1 159 ? 127.070 113.452 134.293 1.00 51.41  ? 159 ILE A CB  1 
ATOM   1189 C CG1 . ILE A 1 159 ? 128.058 112.691 135.177 1.00 51.41  ? 159 ILE A CG1 1 
ATOM   1190 C CG2 . ILE A 1 159 ? 127.243 113.077 132.831 1.00 51.41  ? 159 ILE A CG2 1 
ATOM   1191 C CD1 . ILE A 1 159 ? 128.183 111.221 134.841 1.00 51.41  ? 159 ILE A CD1 1 
ATOM   1192 N N   . PRO A 1 160 ? 125.096 115.871 133.552 1.00 44.37  ? 160 PRO A N   1 
ATOM   1193 C CA  . PRO A 1 160 ? 124.364 116.580 132.484 1.00 44.37  ? 160 PRO A CA  1 
ATOM   1194 C C   . PRO A 1 160 ? 124.736 118.045 132.345 1.00 44.37  ? 160 PRO A C   1 
ATOM   1195 O O   . PRO A 1 160 ? 124.714 118.578 131.226 1.00 44.37  ? 160 PRO A O   1 
ATOM   1196 C CB  . PRO A 1 160 ? 122.895 116.415 132.894 1.00 44.37  ? 160 PRO A CB  1 
ATOM   1197 C CG  . PRO A 1 160 ? 122.874 115.226 133.759 1.00 44.37  ? 160 PRO A CG  1 
ATOM   1198 C CD  . PRO A 1 160 ? 124.154 115.290 134.527 1.00 44.37  ? 160 PRO A CD  1 
ATOM   1199 N N   . ILE A 1 161 ? 125.081 118.710 133.450 1.00 42.54  ? 161 ILE A N   1 
ATOM   1200 C CA  . ILE A 1 161 ? 125.420 120.128 133.397 1.00 42.54  ? 161 ILE A CA  1 
ATOM   1201 C C   . ILE A 1 161 ? 126.666 120.351 132.550 1.00 42.54  ? 161 ILE A C   1 
ATOM   1202 O O   . ILE A 1 161 ? 126.683 121.203 131.653 1.00 42.54  ? 161 ILE A O   1 
ATOM   1203 C CB  . ILE A 1 161 ? 125.611 120.685 134.816 1.00 42.54  ? 161 ILE A CB  1 
ATOM   1204 C CG1 . ILE A 1 161 ? 124.266 120.778 135.540 1.00 42.54  ? 161 ILE A CG1 1 
ATOM   1205 C CG2 . ILE A 1 161 ? 126.300 122.031 134.752 1.00 42.54  ? 161 ILE A CG2 1 
ATOM   1206 C CD1 . ILE A 1 161 ? 124.232 121.818 136.638 1.00 42.54  ? 161 ILE A CD1 1 
ATOM   1207 N N   . VAL A 1 162 ? 127.724 119.582 132.818 1.00 41.25  ? 162 VAL A N   1 
ATOM   1208 C CA  . VAL A 1 162 ? 128.949 119.713 132.038 1.00 41.25  ? 162 VAL A CA  1 
ATOM   1209 C C   . VAL A 1 162 ? 128.702 119.291 130.596 1.00 41.25  ? 162 VAL A C   1 
ATOM   1210 O O   . VAL A 1 162 ? 129.296 119.849 129.665 1.00 41.25  ? 162 VAL A O   1 
ATOM   1211 C CB  . VAL A 1 162 ? 130.078 118.900 132.700 1.00 41.25  ? 162 VAL A CB  1 
ATOM   1212 C CG1 . VAL A 1 162 ? 131.319 118.876 131.827 1.00 41.25  ? 162 VAL A CG1 1 
ATOM   1213 C CG2 . VAL A 1 162 ? 130.403 119.470 134.072 1.00 41.25  ? 162 VAL A CG2 1 
ATOM   1214 N N   . TYR A 1 163 ? 127.804 118.325 130.388 1.00 38.51  ? 163 TYR A N   1 
ATOM   1215 C CA  . TYR A 1 163 ? 127.447 117.896 129.039 1.00 38.51  ? 163 TYR A CA  1 
ATOM   1216 C C   . TYR A 1 163 ? 126.856 119.040 128.224 1.00 38.51  ? 163 TYR A C   1 
ATOM   1217 O O   . TYR A 1 163 ? 127.295 119.299 127.094 1.00 38.51  ? 163 TYR A O   1 
ATOM   1218 C CB  . TYR A 1 163 ? 126.452 116.739 129.126 1.00 38.51  ? 163 TYR A CB  1 
ATOM   1219 C CG  . TYR A 1 163 ? 125.862 116.300 127.808 1.00 38.51  ? 163 TYR A CG  1 
ATOM   1220 C CD1 . TYR A 1 163 ? 126.661 115.765 126.811 1.00 38.51  ? 163 TYR A CD1 1 
ATOM   1221 C CD2 . TYR A 1 163 ? 124.501 116.428 127.562 1.00 38.51  ? 163 TYR A CD2 1 
ATOM   1222 C CE1 . TYR A 1 163 ? 126.120 115.358 125.609 1.00 38.51  ? 163 TYR A CE1 1 
ATOM   1223 C CE2 . TYR A 1 163 ? 123.953 116.027 126.364 1.00 38.51  ? 163 TYR A CE2 1 
ATOM   1224 C CZ  . TYR A 1 163 ? 124.766 115.494 125.391 1.00 38.51  ? 163 TYR A CZ  1 
ATOM   1225 O OH  . TYR A 1 163 ? 124.218 115.095 124.196 1.00 38.51  ? 163 TYR A OH  1 
ATOM   1226 N N   . THR A 1 164 ? 125.865 119.743 128.784 1.00 37.90  ? 164 THR A N   1 
ATOM   1227 C CA  . THR A 1 164 ? 125.204 120.817 128.045 1.00 37.90  ? 164 THR A CA  1 
ATOM   1228 C C   . THR A 1 164 ? 126.130 122.002 127.811 1.00 37.90  ? 164 THR A C   1 
ATOM   1229 O O   . THR A 1 164 ? 125.984 122.709 126.807 1.00 37.90  ? 164 THR A O   1 
ATOM   1230 C CB  . THR A 1 164 ? 123.946 121.282 128.781 1.00 37.90  ? 164 THR A CB  1 
ATOM   1231 O OG1 . THR A 1 164 ? 124.313 121.845 130.048 1.00 37.90  ? 164 THR A OG1 1 
ATOM   1232 C CG2 . THR A 1 164 ? 122.979 120.128 128.989 1.00 37.90  ? 164 THR A CG2 1 
ATOM   1233 N N   . LEU A 1 165 ? 127.069 122.245 128.725 1.00 42.49  ? 165 LEU A N   1 
ATOM   1234 C CA  . LEU A 1 165 ? 128.017 123.340 128.541 1.00 42.49  ? 165 LEU A CA  1 
ATOM   1235 C C   . LEU A 1 165 ? 128.914 123.103 127.336 1.00 42.49  ? 165 LEU A C   1 
ATOM   1236 O O   . LEU A 1 165 ? 129.082 123.987 126.488 1.00 42.49  ? 165 LEU A O   1 
ATOM   1237 C CB  . LEU A 1 165 ? 128.864 123.519 129.800 1.00 42.49  ? 165 LEU A CB  1 
ATOM   1238 C CG  . LEU A 1 165 ? 128.143 124.044 131.034 1.00 42.49  ? 165 LEU A CG  1 
ATOM   1239 C CD1 . LEU A 1 165 ? 129.143 124.464 132.084 1.00 42.49  ? 165 LEU A CD1 1 
ATOM   1240 C CD2 . LEU A 1 165 ? 127.274 125.210 130.639 1.00 42.49  ? 165 LEU A CD2 1 
ATOM   1241 N N   . THR A 1 166 ? 129.503 121.914 127.247 1.00 40.32  ? 166 THR A N   1 
ATOM   1242 C CA  . THR A 1 166 ? 130.537 121.676 126.253 1.00 40.32  ? 166 THR A CA  1 
ATOM   1243 C C   . THR A 1 166 ? 129.953 121.248 124.906 1.00 40.32  ? 166 THR A C   1 
ATOM   1244 O O   . THR A 1 166 ? 130.568 121.516 123.866 1.00 40.32  ? 166 THR A O   1 
ATOM   1245 C CB  . THR A 1 166 ? 131.531 120.653 126.823 1.00 40.32  ? 166 THR A CB  1 
ATOM   1246 O OG1 . THR A 1 166 ? 132.444 121.331 127.694 1.00 40.32  ? 166 THR A OG1 1 
ATOM   1247 C CG2 . THR A 1 166 ? 132.365 120.018 125.743 1.00 40.32  ? 166 THR A CG2 1 
ATOM   1248 N N   . TYR A 1 167 ? 128.749 120.656 124.891 1.00 36.20  ? 167 TYR A N   1 
ATOM   1249 C CA  . TYR A 1 167 ? 128.103 120.300 123.628 1.00 36.20  ? 167 TYR A CA  1 
ATOM   1250 C C   . TYR A 1 167 ? 127.914 121.510 122.721 1.00 36.20  ? 167 TYR A C   1 
ATOM   1251 O O   . TYR A 1 167 ? 127.975 121.376 121.494 1.00 36.20  ? 167 TYR A O   1 
ATOM   1252 C CB  . TYR A 1 167 ? 126.759 119.619 123.912 1.00 36.20  ? 167 TYR A CB  1 
ATOM   1253 C CG  . TYR A 1 167 ? 126.170 118.802 122.772 1.00 36.20  ? 167 TYR A CG  1 
ATOM   1254 C CD1 . TYR A 1 167 ? 125.690 119.410 121.620 1.00 36.20  ? 167 TYR A CD1 1 
ATOM   1255 C CD2 . TYR A 1 167 ? 126.096 117.418 122.853 1.00 36.20  ? 167 TYR A CD2 1 
ATOM   1256 C CE1 . TYR A 1 167 ? 125.153 118.670 120.587 1.00 36.20  ? 167 TYR A CE1 1 
ATOM   1257 C CE2 . TYR A 1 167 ? 125.560 116.668 121.822 1.00 36.20  ? 167 TYR A CE2 1 
ATOM   1258 C CZ  . TYR A 1 167 ? 125.091 117.300 120.693 1.00 36.20  ? 167 TYR A CZ  1 
ATOM   1259 O OH  . TYR A 1 167 ? 124.556 116.560 119.663 1.00 36.20  ? 167 TYR A OH  1 
ATOM   1260 N N   . VAL A 1 168 ? 127.697 122.694 123.300 1.00 39.54  ? 168 VAL A N   1 
ATOM   1261 C CA  . VAL A 1 168 ? 127.456 123.889 122.494 1.00 39.54  ? 168 VAL A CA  1 
ATOM   1262 C C   . VAL A 1 168 ? 128.664 124.192 121.616 1.00 39.54  ? 168 VAL A C   1 
ATOM   1263 O O   . VAL A 1 168 ? 128.532 124.462 120.416 1.00 39.54  ? 168 VAL A O   1 
ATOM   1264 C CB  . VAL A 1 168 ? 127.105 125.084 123.398 1.00 39.54  ? 168 VAL A CB  1 
ATOM   1265 C CG1 . VAL A 1 168 ? 127.197 126.392 122.624 1.00 39.54  ? 168 VAL A CG1 1 
ATOM   1266 C CG2 . VAL A 1 168 ? 125.724 124.906 124.004 1.00 39.54  ? 168 VAL A CG2 1 
ATOM   1267 N N   . PHE A 1 169 ? 129.865 124.136 122.195 1.00 45.26  ? 169 PHE A N   1 
ATOM   1268 C CA  . PHE A 1 169 ? 131.052 124.456 121.411 1.00 45.26  ? 169 PHE A CA  1 
ATOM   1269 C C   . PHE A 1 169 ? 131.434 123.334 120.457 1.00 45.26  ? 169 PHE A C   1 
ATOM   1270 O O   . PHE A 1 169 ? 131.971 123.607 119.379 1.00 45.26  ? 169 PHE A O   1 
ATOM   1271 C CB  . PHE A 1 169 ? 132.239 124.770 122.314 1.00 45.26  ? 169 PHE A CB  1 
ATOM   1272 C CG  . PHE A 1 169 ? 133.482 125.133 121.555 1.00 45.26  ? 169 PHE A CG  1 
ATOM   1273 C CD1 . PHE A 1 169 ? 133.582 126.350 120.902 1.00 45.26  ? 169 PHE A CD1 1 
ATOM   1274 C CD2 . PHE A 1 169 ? 134.530 124.236 121.453 1.00 45.26  ? 169 PHE A CD2 1 
ATOM   1275 C CE1 . PHE A 1 169 ? 134.722 126.677 120.188 1.00 45.26  ? 169 PHE A CE1 1 
ATOM   1276 C CE2 . PHE A 1 169 ? 135.667 124.555 120.739 1.00 45.26  ? 169 PHE A CE2 1 
ATOM   1277 C CZ  . PHE A 1 169 ? 135.765 125.777 120.108 1.00 45.26  ? 169 PHE A CZ  1 
ATOM   1278 N N   . GLY A 1 170 ? 131.188 122.079 120.836 1.00 42.74  ? 170 GLY A N   1 
ATOM   1279 C CA  . GLY A 1 170 ? 131.697 120.968 120.047 1.00 42.74  ? 170 GLY A CA  1 
ATOM   1280 C C   . GLY A 1 170 ? 131.153 120.948 118.632 1.00 42.74  ? 170 GLY A C   1 
ATOM   1281 O O   . GLY A 1 170 ? 131.917 120.945 117.664 1.00 42.74  ? 170 GLY A O   1 
ATOM   1282 N N   . THR A 1 171 ? 129.827 121.010 118.493 1.00 38.23  ? 171 THR A N   1 
ATOM   1283 C CA  . THR A 1 171 ? 129.224 120.871 117.173 1.00 38.23  ? 171 THR A CA  1 
ATOM   1284 C C   . THR A 1 171 ? 129.603 122.032 116.265 1.00 38.23  ? 171 THR A C   1 
ATOM   1285 O O   . THR A 1 171 ? 130.119 121.818 115.163 1.00 38.23  ? 171 THR A O   1 
ATOM   1286 C CB  . THR A 1 171 ? 127.705 120.769 117.300 1.00 38.23  ? 171 THR A CB  1 
ATOM   1287 O OG1 . THR A 1 171 ? 127.354 119.489 117.838 1.00 38.23  ? 171 THR A OG1 1 
ATOM   1288 C CG2 . THR A 1 171 ? 127.043 120.940 115.942 1.00 38.23  ? 171 THR A CG2 1 
ATOM   1289 N N   . ILE A 1 172 ? 129.414 123.265 116.736 1.00 41.54  ? 172 ILE A N   1 
ATOM   1290 C CA  . ILE A 1 172 ? 129.681 124.433 115.903 1.00 41.54  ? 172 ILE A CA  1 
ATOM   1291 C C   . ILE A 1 172 ? 131.167 124.526 115.575 1.00 41.54  ? 172 ILE A C   1 
ATOM   1292 O O   . ILE A 1 172 ? 131.553 124.720 114.414 1.00 41.54  ? 172 ILE A O   1 
ATOM   1293 C CB  . ILE A 1 172 ? 129.173 125.709 116.598 1.00 41.54  ? 172 ILE A CB  1 
ATOM   1294 C CG1 . ILE A 1 172 ? 127.677 125.895 116.348 1.00 41.54  ? 172 ILE A CG1 1 
ATOM   1295 C CG2 . ILE A 1 172 ? 129.955 126.931 116.133 1.00 41.54  ? 172 ILE A CG2 1 
ATOM   1296 C CD1 . ILE A 1 172 ? 127.150 127.249 116.777 1.00 41.54  ? 172 ILE A CD1 1 
ATOM   1297 N N   . GLY A 1 173 ? 132.021 124.359 116.587 1.00 44.43  ? 173 GLY A N   1 
ATOM   1298 C CA  . GLY A 1 173 ? 133.450 124.502 116.366 1.00 44.43  ? 173 GLY A CA  1 
ATOM   1299 C C   . GLY A 1 173 ? 134.014 123.457 115.425 1.00 44.43  ? 173 GLY A C   1 
ATOM   1300 O O   . GLY A 1 173 ? 134.746 123.786 114.486 1.00 44.43  ? 173 GLY A O   1 
ATOM   1301 N N   . VAL A 1 174 ? 133.676 122.184 115.648 1.00 41.39  ? 174 VAL A N   1 
ATOM   1302 C CA  . VAL A 1 174 ? 134.238 121.147 114.792 1.00 41.39  ? 174 VAL A CA  1 
ATOM   1303 C C   . VAL A 1 174 ? 133.610 121.202 113.404 1.00 41.39  ? 174 VAL A C   1 
ATOM   1304 O O   . VAL A 1 174 ? 134.272 120.900 112.404 1.00 41.39  ? 174 VAL A O   1 
ATOM   1305 C CB  . VAL A 1 174 ? 134.094 119.762 115.444 1.00 41.39  ? 174 VAL A CB  1 
ATOM   1306 C CG1 . VAL A 1 174 ? 134.764 118.709 114.589 1.00 41.39  ? 174 VAL A CG1 1 
ATOM   1307 C CG2 . VAL A 1 174 ? 134.733 119.770 116.809 1.00 41.39  ? 174 VAL A CG2 1 
ATOM   1308 N N   . LEU A 1 175 ? 132.338 121.607 113.307 1.00 41.34  ? 175 LEU A N   1 
ATOM   1309 C CA  . LEU A 1 175 ? 131.726 121.797 111.997 1.00 41.34  ? 175 LEU A CA  1 
ATOM   1310 C C   . LEU A 1 175 ? 132.471 122.855 111.193 1.00 41.34  ? 175 LEU A C   1 
ATOM   1311 O O   . LEU A 1 175 ? 132.820 122.634 110.026 1.00 41.34  ? 175 LEU A O   1 
ATOM   1312 C CB  . LEU A 1 175 ? 130.259 122.185 112.165 1.00 41.34  ? 175 LEU A CB  1 
ATOM   1313 C CG  . LEU A 1 175 ? 129.454 122.387 110.879 1.00 41.34  ? 175 LEU A CG  1 
ATOM   1314 C CD1 . LEU A 1 175 ? 128.808 121.088 110.427 1.00 41.34  ? 175 LEU A CD1 1 
ATOM   1315 C CD2 . LEU A 1 175 ? 128.412 123.476 111.073 1.00 41.34  ? 175 LEU A CD2 1 
ATOM   1316 N N   . ILE A 1 176 ? 132.751 124.002 111.816 1.00 42.37  ? 176 ILE A N   1 
ATOM   1317 C CA  . ILE A 1 176 ? 133.486 125.062 111.130 1.00 42.37  ? 176 ILE A CA  1 
ATOM   1318 C C   . ILE A 1 176 ? 134.885 124.583 110.757 1.00 42.37  ? 176 ILE A C   1 
ATOM   1319 O O   . ILE A 1 176 ? 135.350 124.790 109.627 1.00 42.37  ? 176 ILE A O   1 
ATOM   1320 C CB  . ILE A 1 176 ? 133.523 126.331 112.005 1.00 42.37  ? 176 ILE A CB  1 
ATOM   1321 C CG1 . ILE A 1 176 ? 132.316 127.218 111.702 1.00 42.37  ? 176 ILE A CG1 1 
ATOM   1322 C CG2 . ILE A 1 176 ? 134.808 127.118 111.787 1.00 42.37  ? 176 ILE A CG2 1 
ATOM   1323 C CD1 . ILE A 1 176 ? 132.222 128.446 112.580 1.00 42.37  ? 176 ILE A CD1 1 
ATOM   1324 N N   . PHE A 1 177 ? 135.557 123.896 111.688 1.00 42.95  ? 177 PHE A N   1 
ATOM   1325 C CA  . PHE A 1 177 ? 136.933 123.468 111.459 1.00 42.95  ? 177 PHE A CA  1 
ATOM   1326 C C   . PHE A 1 177 ? 137.028 122.442 110.335 1.00 42.95  ? 177 PHE A C   1 
ATOM   1327 O O   . PHE A 1 177 ? 137.968 122.477 109.534 1.00 42.95  ? 177 PHE A O   1 
ATOM   1328 C CB  . PHE A 1 177 ? 137.521 122.903 112.750 1.00 42.95  ? 177 PHE A CB  1 
ATOM   1329 C CG  . PHE A 1 177 ? 138.962 122.511 112.635 1.00 42.95  ? 177 PHE A CG  1 
ATOM   1330 C CD1 . PHE A 1 177 ? 139.911 123.434 112.236 1.00 42.95  ? 177 PHE A CD1 1 
ATOM   1331 C CD2 . PHE A 1 177 ? 139.371 121.224 112.936 1.00 42.95  ? 177 PHE A CD2 1 
ATOM   1332 C CE1 . PHE A 1 177 ? 141.239 123.082 112.131 1.00 42.95  ? 177 PHE A CE1 1 
ATOM   1333 C CE2 . PHE A 1 177 ? 140.699 120.867 112.836 1.00 42.95  ? 177 PHE A CE2 1 
ATOM   1334 C CZ  . PHE A 1 177 ? 141.633 121.796 112.429 1.00 42.95  ? 177 PHE A CZ  1 
ATOM   1335 N N   . LEU A 1 178 ? 136.073 121.516 110.262 1.00 41.83  ? 178 LEU A N   1 
ATOM   1336 C CA  . LEU A 1 178 ? 136.099 120.477 109.244 1.00 41.83  ? 178 LEU A CA  1 
ATOM   1337 C C   . LEU A 1 178 ? 135.440 120.893 107.939 1.00 41.83  ? 178 LEU A C   1 
ATOM   1338 O O   . LEU A 1 178 ? 135.551 120.159 106.952 1.00 41.83  ? 178 LEU A O   1 
ATOM   1339 C CB  . LEU A 1 178 ? 135.416 119.203 109.751 1.00 41.83  ? 178 LEU A CB  1 
ATOM   1340 C CG  . LEU A 1 178 ? 136.106 118.431 110.871 1.00 41.83  ? 178 LEU A CG  1 
ATOM   1341 C CD1 . LEU A 1 178 ? 135.273 117.225 111.280 1.00 41.83  ? 178 LEU A CD1 1 
ATOM   1342 C CD2 . LEU A 1 178 ? 137.493 118.014 110.438 1.00 41.83  ? 178 LEU A CD2 1 
ATOM   1343 N N   . ARG A 1 179 ? 134.751 122.031 107.899 1.00 51.47  ? 179 ARG A N   1 
ATOM   1344 C CA  . ARG A 1 179 ? 134.124 122.456 106.656 1.00 51.47  ? 179 ARG A CA  1 
ATOM   1345 C C   . ARG A 1 179 ? 134.861 123.587 105.953 1.00 51.47  ? 179 ARG A C   1 
ATOM   1346 O O   . ARG A 1 179 ? 134.851 123.642 104.721 1.00 51.47  ? 179 ARG A O   1 
ATOM   1347 C CB  . ARG A 1 179 ? 132.676 122.875 106.910 1.00 51.47  ? 179 ARG A CB  1 
ATOM   1348 C CG  . ARG A 1 179 ? 131.748 122.555 105.757 1.00 51.47  ? 179 ARG A CG  1 
ATOM   1349 C CD  . ARG A 1 179 ? 130.404 123.220 105.942 1.00 51.47  ? 179 ARG A CD  1 
ATOM   1350 N NE  . ARG A 1 179 ? 130.534 124.641 106.240 1.00 51.47  ? 179 ARG A NE  1 
ATOM   1351 C CZ  . ARG A 1 179 ? 129.794 125.285 107.131 1.00 51.47  ? 179 ARG A CZ  1 
ATOM   1352 N NH1 . ARG A 1 179 ? 128.861 124.663 107.832 1.00 51.47  ? 179 ARG A NH1 1 
ATOM   1353 N NH2 . ARG A 1 179 ? 129.995 126.586 107.323 1.00 51.47  ? 179 ARG A NH2 1 
ATOM   1354 N N   . ASP A 1 180 ? 135.489 124.504 106.689 1.00 53.94  ? 180 ASP A N   1 
ATOM   1355 C CA  . ASP A 1 180 ? 136.150 125.641 106.057 1.00 53.94  ? 180 ASP A CA  1 
ATOM   1356 C C   . ASP A 1 180 ? 137.655 125.656 106.273 1.00 53.94  ? 180 ASP A C   1 
ATOM   1357 O O   . ASP A 1 180 ? 138.415 125.802 105.303 1.00 53.94  ? 180 ASP A O   1 
ATOM   1358 C CB  . ASP A 1 180 ? 135.545 126.959 106.569 1.00 53.94  ? 180 ASP A CB  1 
ATOM   1359 C CG  . ASP A 1 180 ? 134.086 127.127 106.183 1.00 53.94  ? 180 ASP A CG  1 
ATOM   1360 O OD1 . ASP A 1 180 ? 133.526 126.226 105.525 1.00 53.94  ? 180 ASP A OD1 1 
ATOM   1361 O OD2 . ASP A 1 180 ? 133.497 128.169 106.539 1.00 53.94  ? 180 ASP A OD2 1 
ATOM   1362 N N   . ILE A 1 181 ? 138.107 125.510 107.520 1.00 51.01  ? 181 ILE A N   1 
ATOM   1363 C CA  . ILE A 1 181 ? 139.514 125.732 107.841 1.00 51.01  ? 181 ILE A CA  1 
ATOM   1364 C C   . ILE A 1 181 ? 140.396 124.681 107.177 1.00 51.01  ? 181 ILE A C   1 
ATOM   1365 O O   . ILE A 1 181 ? 141.419 125.009 106.568 1.00 51.01  ? 181 ILE A O   1 
ATOM   1366 C CB  . ILE A 1 181 ? 139.716 125.760 109.366 1.00 51.01  ? 181 ILE A CB  1 
ATOM   1367 C CG1 . ILE A 1 181 ? 139.018 126.980 109.974 1.00 51.01  ? 181 ILE A CG1 1 
ATOM   1368 C CG2 . ILE A 1 181 ? 141.194 125.765 109.713 1.00 51.01  ? 181 ILE A CG2 1 
ATOM   1369 C CD1 . ILE A 1 181 ? 139.614 128.306 109.548 1.00 51.01  ? 181 ILE A CD1 1 
ATOM   1370 N N   . MET A 1 182 ? 140.024 123.407 107.293 1.00 54.66  ? 182 MET A N   1 
ATOM   1371 C CA  . MET A 1 182 ? 140.817 122.351 106.664 1.00 54.66  ? 182 MET A CA  1 
ATOM   1372 C C   . MET A 1 182 ? 140.841 122.439 105.139 1.00 54.66  ? 182 MET A C   1 
ATOM   1373 O O   . MET A 1 182 ? 141.924 122.248 104.556 1.00 54.66  ? 182 MET A O   1 
ATOM   1374 C CB  . MET A 1 182 ? 140.335 120.978 107.148 1.00 54.66  ? 182 MET A CB  1 
ATOM   1375 C CG  . MET A 1 182 ? 141.371 119.876 106.972 1.00 54.66  ? 182 MET A CG  1 
ATOM   1376 S SD  . MET A 1 182 ? 141.197 118.509 108.132 1.00 54.66  ? 182 MET A SD  1 
ATOM   1377 C CE  . MET A 1 182 ? 141.164 119.398 109.681 1.00 54.66  ? 182 MET A CE  1 
ATOM   1378 N N   . PRO A 1 183 ? 139.725 122.675 104.431 1.00 57.54  ? 183 PRO A N   1 
ATOM   1379 C CA  . PRO A 1 183 ? 139.846 122.931 102.984 1.00 57.54  ? 183 PRO A CA  1 
ATOM   1380 C C   . PRO A 1 183 ? 140.689 124.149 102.642 1.00 57.54  ? 183 PRO A C   1 
ATOM   1381 O O   . PRO A 1 183 ? 141.417 124.114 101.641 1.00 57.54  ? 183 PRO A O   1 
ATOM   1382 C CB  . PRO A 1 183 ? 138.390 123.096 102.527 1.00 57.54  ? 183 PRO A CB  1 
ATOM   1383 C CG  . PRO A 1 183 ? 137.590 122.405 103.550 1.00 57.54  ? 183 PRO A CG  1 
ATOM   1384 C CD  . PRO A 1 183 ? 138.309 122.586 104.838 1.00 57.54  ? 183 PRO A CD  1 
ATOM   1385 N N   . LYS A 1 184 ? 140.632 125.221 103.440 1.00 57.34  ? 184 LYS A N   1 
ATOM   1386 C CA  . LYS A 1 184 ? 141.511 126.358 103.174 1.00 57.34  ? 184 LYS A CA  1 
ATOM   1387 C C   . LYS A 1 184 ? 142.975 125.979 103.353 1.00 57.34  ? 184 LYS A C   1 
ATOM   1388 O O   . LYS A 1 184 ? 143.835 126.415 102.579 1.00 57.34  ? 184 LYS A O   1 
ATOM   1389 C CB  . LYS A 1 184 ? 141.148 127.543 104.069 1.00 57.34  ? 184 LYS A CB  1 
ATOM   1390 C CG  . LYS A 1 184 ? 140.023 128.405 103.522 1.00 57.34  ? 184 LYS A CG  1 
ATOM   1391 C CD  . LYS A 1 184 ? 139.218 129.051 104.635 1.00 57.34  ? 184 LYS A CD  1 
ATOM   1392 C CE  . LYS A 1 184 ? 137.961 129.706 104.088 1.00 57.34  ? 184 LYS A CE  1 
ATOM   1393 N NZ  . LYS A 1 184 ? 137.182 130.402 105.148 1.00 57.34  ? 184 LYS A NZ  1 
ATOM   1394 N N   . LEU A 1 185 ? 143.279 125.172 104.372 1.00 59.19  ? 185 LEU A N   1 
ATOM   1395 C CA  . LEU A 1 185 ? 144.658 124.748 104.594 1.00 59.19  ? 185 LEU A CA  1 
ATOM   1396 C C   . LEU A 1 185 ? 145.153 123.833 103.480 1.00 59.19  ? 185 LEU A C   1 
ATOM   1397 O O   . LEU A 1 185 ? 146.311 123.935 103.060 1.00 59.19  ? 185 LEU A O   1 
ATOM   1398 C CB  . LEU A 1 185 ? 144.794 124.062 105.954 1.00 59.19  ? 185 LEU A CB  1 
ATOM   1399 C CG  . LEU A 1 185 ? 144.534 124.916 107.198 1.00 59.19  ? 185 LEU A CG  1 
ATOM   1400 C CD1 . LEU A 1 185 ? 145.172 124.285 108.424 1.00 59.19  ? 185 LEU A CD1 1 
ATOM   1401 C CD2 . LEU A 1 185 ? 145.041 126.338 107.003 1.00 59.19  ? 185 LEU A CD2 1 
ATOM   1402 N N   . MET A 1 186 ? 144.304 122.932 102.989 1.00 67.50  ? 186 MET A N   1 
ATOM   1403 C CA  . MET A 1 186 ? 144.736 122.040 101.919 1.00 67.50  ? 186 MET A CA  1 
ATOM   1404 C C   . MET A 1 186 ? 144.654 122.671 100.535 1.00 67.50  ? 186 MET A C   1 
ATOM   1405 O O   . MET A 1 186 ? 145.153 122.070 99.577  1.00 67.50  ? 186 MET A O   1 
ATOM   1406 C CB  . MET A 1 186 ? 143.928 120.739 101.921 1.00 67.50  ? 186 MET A CB  1 
ATOM   1407 C CG  . MET A 1 186 ? 144.639 119.579 102.601 1.00 67.50  ? 186 MET A CG  1 
ATOM   1408 S SD  . MET A 1 186 ? 143.631 118.089 102.710 1.00 67.50  ? 186 MET A SD  1 
ATOM   1409 C CE  . MET A 1 186 ? 142.279 118.659 103.727 1.00 67.50  ? 186 MET A CE  1 
ATOM   1410 N N   . HIS A 1 187 ? 144.054 123.860 100.414 1.00 71.37  ? 187 HIS A N   1 
ATOM   1411 C CA  . HIS A 1 187 ? 143.967 124.592 99.147  1.00 71.37  ? 187 HIS A CA  1 
ATOM   1412 C C   . HIS A 1 187 ? 143.220 123.784 98.084  1.00 71.37  ? 187 HIS A C   1 
ATOM   1413 O O   . HIS A 1 187 ? 143.616 123.729 96.919  1.00 71.37  ? 187 HIS A O   1 
ATOM   1414 C CB  . HIS A 1 187 ? 145.358 125.000 98.648  1.00 71.37  ? 187 HIS A CB  1 
ATOM   1415 C CG  . HIS A 1 187 ? 145.937 126.181 99.361  1.00 71.37  ? 187 HIS A CG  1 
ATOM   1416 N ND1 . HIS A 1 187 ? 145.158 127.115 100.011 1.00 71.37  ? 187 HIS A ND1 1 
ATOM   1417 C CD2 . HIS A 1 187 ? 147.220 126.578 99.532  1.00 71.37  ? 187 HIS A CD2 1 
ATOM   1418 C CE1 . HIS A 1 187 ? 145.937 128.038 100.547 1.00 71.37  ? 187 HIS A CE1 1 
ATOM   1419 N NE2 . HIS A 1 187 ? 147.192 127.735 100.272 1.00 71.37  ? 187 HIS A NE2 1 
ATOM   1420 N N   . ILE A 1 188 ? 142.120 123.154 98.501  1.00 76.97  ? 188 ILE A N   1 
ATOM   1421 C CA  . ILE A 1 188 ? 141.273 122.365 97.617  1.00 76.97  ? 188 ILE A CA  1 
ATOM   1422 C C   . ILE A 1 188 ? 139.840 122.866 97.731  1.00 76.97  ? 188 ILE A C   1 
ATOM   1423 O O   . ILE A 1 188 ? 139.466 123.546 98.689  1.00 76.97  ? 188 ILE A O   1 
ATOM   1424 C CB  . ILE A 1 188 ? 141.326 120.848 97.926  1.00 76.97  ? 188 ILE A CB  1 
ATOM   1425 C CG1 . ILE A 1 188 ? 140.289 120.475 98.991  1.00 76.97  ? 188 ILE A CG1 1 
ATOM   1426 C CG2 . ILE A 1 188 ? 142.720 120.413 98.343  1.00 76.97  ? 188 ILE A CG2 1 
ATOM   1427 C CD1 . ILE A 1 188 ? 140.148 118.990 99.216  1.00 76.97  ? 188 ILE A CD1 1 
ATOM   1428 N N   . ASP A 1 189 ? 139.042 122.538 96.720  1.00 82.34  ? 189 ASP A N   1 
ATOM   1429 C CA  . ASP A 1 189 ? 137.604 122.751 96.767  1.00 82.34  ? 189 ASP A CA  1 
ATOM   1430 C C   . ASP A 1 189 ? 136.895 121.430 97.029  1.00 82.34  ? 189 ASP A C   1 
ATOM   1431 O O   . ASP A 1 189 ? 137.204 120.407 96.404  1.00 82.34  ? 189 ASP A O   1 
ATOM   1432 C CB  . ASP A 1 189 ? 137.092 123.385 95.474  1.00 82.34  ? 189 ASP A CB  1 
ATOM   1433 C CG  . ASP A 1 189 ? 136.903 124.885 95.601  1.00 82.34  ? 189 ASP A CG  1 
ATOM   1434 O OD1 . ASP A 1 189 ? 137.223 125.434 96.678  1.00 82.34  ? 189 ASP A OD1 1 
ATOM   1435 O OD2 . ASP A 1 189 ? 136.433 125.514 94.631  1.00 82.34  ? 189 ASP A OD2 1 
ATOM   1436 N N   . LEU A 1 190 ? 135.938 121.469 97.961  1.00 75.39  ? 190 LEU A N   1 
ATOM   1437 C CA  . LEU A 1 190 ? 135.266 120.257 98.418  1.00 75.39  ? 190 LEU A CA  1 
ATOM   1438 C C   . LEU A 1 190 ? 134.513 119.568 97.292  1.00 75.39  ? 190 LEU A C   1 
ATOM   1439 O O   . LEU A 1 190 ? 134.504 118.334 97.217  1.00 75.39  ? 190 LEU A O   1 
ATOM   1440 C CB  . LEU A 1 190 ? 134.305 120.600 99.555  1.00 75.39  ? 190 LEU A CB  1 
ATOM   1441 C CG  . LEU A 1 190 ? 134.192 119.602 100.704 1.00 75.39  ? 190 LEU A CG  1 
ATOM   1442 C CD1 . LEU A 1 190 ? 135.498 119.522 101.471 1.00 75.39  ? 190 LEU A CD1 1 
ATOM   1443 C CD2 . LEU A 1 190 ? 133.052 120.003 101.622 1.00 75.39  ? 190 LEU A CD2 1 
ATOM   1444 N N   . LYS A 1 191 ? 133.874 120.341 96.417  1.00 79.35  ? 191 LYS A N   1 
ATOM   1445 C CA  . LYS A 1 191 ? 133.168 119.753 95.285  1.00 79.35  ? 191 LYS A CA  1 
ATOM   1446 C C   . LYS A 1 191 ? 134.146 119.135 94.291  1.00 79.35  ? 191 LYS A C   1 
ATOM   1447 O O   . LYS A 1 191 ? 134.024 117.957 93.929  1.00 79.35  ? 191 LYS A O   1 
ATOM   1448 C CB  . LYS A 1 191 ? 132.317 120.829 94.608  1.00 79.35  ? 191 LYS A CB  1 
ATOM   1449 C CG  . LYS A 1 191 ? 131.873 120.505 93.195  1.00 79.35  ? 191 LYS A CG  1 
ATOM   1450 C CD  . LYS A 1 191 ? 130.529 119.801 93.185  1.00 79.35  ? 191 LYS A CD  1 
ATOM   1451 C CE  . LYS A 1 191 ? 129.469 120.659 93.861  1.00 79.35  ? 191 LYS A CE  1 
ATOM   1452 N NZ  . LYS A 1 191 ? 128.141 119.993 93.891  1.00 79.35  ? 191 LYS A NZ  1 
ATOM   1453 N N   . LYS A 1 192 ? 135.160 119.904 93.887  1.00 82.96  ? 192 LYS A N   1 
ATOM   1454 C CA  . LYS A 1 192 ? 136.013 119.522 92.766  1.00 82.96  ? 192 LYS A CA  1 
ATOM   1455 C C   . LYS A 1 192 ? 136.915 118.344 93.109  1.00 82.96  ? 192 LYS A C   1 
ATOM   1456 O O   . LYS A 1 192 ? 137.027 117.396 92.323  1.00 82.96  ? 192 LYS A O   1 
ATOM   1457 C CB  . LYS A 1 192 ? 136.855 120.717 92.314  1.00 82.96  ? 192 LYS A CB  1 
ATOM   1458 C CG  . LYS A 1 192 ? 136.049 121.911 91.836  1.00 82.96  ? 192 LYS A CG  1 
ATOM   1459 C CD  . LYS A 1 192 ? 136.689 122.540 90.609  1.00 82.96  ? 192 LYS A CD  1 
ATOM   1460 C CE  . LYS A 1 192 ? 135.821 123.646 90.035  1.00 82.96  ? 192 LYS A CE  1 
ATOM   1461 N NZ  . LYS A 1 192 ? 134.594 123.871 90.847  1.00 82.96  ? 192 LYS A NZ  1 
ATOM   1462 N N   . GLN A 1 193 ? 137.576 118.388 94.270  1.00 85.47  ? 193 GLN A N   1 
ATOM   1463 C CA  . GLN A 1 193 ? 138.495 117.308 94.621  1.00 85.47  ? 193 GLN A CA  1 
ATOM   1464 C C   . GLN A 1 193 ? 137.755 115.992 94.822  1.00 85.47  ? 193 GLN A C   1 
ATOM   1465 O O   . GLN A 1 193 ? 138.235 114.931 94.402  1.00 85.47  ? 193 GLN A O   1 
ATOM   1466 C CB  . GLN A 1 193 ? 139.295 117.676 95.872  1.00 85.47  ? 193 GLN A CB  1 
ATOM   1467 C CG  . GLN A 1 193 ? 140.551 116.833 96.089  1.00 85.47  ? 193 GLN A CG  1 
ATOM   1468 C CD  . GLN A 1 193 ? 141.698 117.193 95.153  1.00 85.47  ? 193 GLN A CD  1 
ATOM   1469 O OE1 . GLN A 1 193 ? 141.524 117.926 94.178  1.00 85.47  ? 193 GLN A OE1 1 
ATOM   1470 N NE2 . GLN A 1 193 ? 142.882 116.673 95.450  1.00 85.47  ? 193 GLN A NE2 1 
ATOM   1471 N N   . ALA A 1 194 ? 136.583 116.042 95.459  1.00 86.57  ? 194 ALA A N   1 
ATOM   1472 C CA  . ALA A 1 194 ? 135.801 114.827 95.656  1.00 86.57  ? 194 ALA A CA  1 
ATOM   1473 C C   . ALA A 1 194 ? 135.290 114.273 94.335  1.00 86.57  ? 194 ALA A C   1 
ATOM   1474 O O   . ALA A 1 194 ? 135.274 113.053 94.135  1.00 86.57  ? 194 ALA A O   1 
ATOM   1475 C CB  . ALA A 1 194 ? 134.644 115.092 96.612  1.00 86.57  ? 194 ALA A CB  1 
ATOM   1476 N N   . VAL A 1 195 ? 134.864 115.150 93.419  1.00 89.02  ? 195 VAL A N   1 
ATOM   1477 C CA  . VAL A 1 195 ? 134.428 114.680 92.106  1.00 89.02  ? 195 VAL A CA  1 
ATOM   1478 C C   . VAL A 1 195 ? 135.583 114.024 91.360  1.00 89.02  ? 195 VAL A C   1 
ATOM   1479 O O   . VAL A 1 195 ? 135.419 112.969 90.736  1.00 89.02  ? 195 VAL A O   1 
ATOM   1480 C CB  . VAL A 1 195 ? 133.811 115.838 91.300  1.00 89.02  ? 195 VAL A CB  1 
ATOM   1481 C CG1 . VAL A 1 195 ? 133.761 115.499 89.818  1.00 89.02  ? 195 VAL A CG1 1 
ATOM   1482 C CG2 . VAL A 1 195 ? 132.417 116.146 91.817  1.00 89.02  ? 195 VAL A CG2 1 
ATOM   1483 N N   . LYS A 1 196 ? 136.771 114.633 91.420  1.00 91.66  ? 196 LYS A N   1 
ATOM   1484 C CA  . LYS A 1 196 ? 137.933 114.053 90.752  1.00 91.66  ? 196 LYS A CA  1 
ATOM   1485 C C   . LYS A 1 196 ? 138.295 112.693 91.339  1.00 91.66  ? 196 LYS A C   1 
ATOM   1486 O O   . LYS A 1 196 ? 138.585 111.744 90.598  1.00 91.66  ? 196 LYS A O   1 
ATOM   1487 C CB  . LYS A 1 196 ? 139.119 115.011 90.842  1.00 91.66  ? 196 LYS A CB  1 
ATOM   1488 C CG  . LYS A 1 196 ? 140.446 114.396 90.438  1.00 91.66  ? 196 LYS A CG  1 
ATOM   1489 C CD  . LYS A 1 196 ? 141.610 115.098 91.117  1.00 91.66  ? 196 LYS A CD  1 
ATOM   1490 C CE  . LYS A 1 196 ? 141.564 116.599 90.882  1.00 91.66  ? 196 LYS A CE  1 
ATOM   1491 N NZ  . LYS A 1 196 ? 142.428 117.331 91.849  1.00 91.66  ? 196 LYS A NZ  1 
ATOM   1492 N N   . THR A 1 197 ? 138.281 112.574 92.669  1.00 93.03  ? 197 THR A N   1 
ATOM   1493 C CA  . THR A 1 197 ? 138.609 111.294 93.289  1.00 93.03  ? 197 THR A CA  1 
ATOM   1494 C C   . THR A 1 197 ? 137.561 110.233 92.962  1.00 93.03  ? 197 THR A C   1 
ATOM   1495 O O   . THR A 1 197 ? 137.904 109.070 92.715  1.00 93.03  ? 197 THR A O   1 
ATOM   1496 C CB  . THR A 1 197 ? 138.759 111.460 94.799  1.00 93.03  ? 197 THR A CB  1 
ATOM   1497 O OG1 . THR A 1 197 ? 139.565 112.613 95.073  1.00 93.03  ? 197 THR A OG1 1 
ATOM   1498 C CG2 . THR A 1 197 ? 139.445 110.240 95.391  1.00 93.03  ? 197 THR A CG2 1 
ATOM   1499 N N   . ALA A 1 198 ? 136.280 110.616 92.949  1.00 97.11  ? 198 ALA A N   1 
ATOM   1500 C CA  . ALA A 1 198 ? 135.227 109.675 92.583  1.00 97.11  ? 198 ALA A CA  1 
ATOM   1501 C C   . ALA A 1 198 ? 135.339 109.249 91.125  1.00 97.11  ? 198 ALA A C   1 
ATOM   1502 O O   . ALA A 1 198 ? 134.996 108.112 90.786  1.00 97.11  ? 198 ALA A O   1 
ATOM   1503 C CB  . ALA A 1 198 ? 133.854 110.288 92.856  1.00 97.11  ? 198 ALA A CB  1 
ATOM   1504 N N   . LYS A 1 199 ? 135.794 110.149 90.250  1.00 100.44 ? 199 LYS A N   1 
ATOM   1505 C CA  . LYS A 1 199 ? 136.052 109.771 88.864  1.00 100.44 ? 199 LYS A CA  1 
ATOM   1506 C C   . LYS A 1 199 ? 137.230 108.811 88.764  1.00 100.44 ? 199 LYS A C   1 
ATOM   1507 O O   . LYS A 1 199 ? 137.223 107.897 87.930  1.00 100.44 ? 199 LYS A O   1 
ATOM   1508 C CB  . LYS A 1 199 ? 136.306 111.016 88.015  1.00 100.44 ? 199 LYS A CB  1 
ATOM   1509 C CG  . LYS A 1 199 ? 135.046 111.695 87.523  1.00 100.44 ? 199 LYS A CG  1 
ATOM   1510 C CD  . LYS A 1 199 ? 134.405 110.889 86.408  1.00 100.44 ? 199 LYS A CD  1 
ATOM   1511 C CE  . LYS A 1 199 ? 133.153 111.571 85.894  1.00 100.44 ? 199 LYS A CE  1 
ATOM   1512 N NZ  . LYS A 1 199 ? 132.049 111.513 86.888  1.00 100.44 ? 199 LYS A NZ  1 
ATOM   1513 N N   . GLU A 1 200 ? 138.261 109.020 89.588  1.00 103.33 ? 200 GLU A N   1 
ATOM   1514 C CA  . GLU A 1 200 ? 139.388 108.090 89.613  1.00 103.33 ? 200 GLU A CA  1 
ATOM   1515 C C   . GLU A 1 200 ? 138.925 106.707 90.052  1.00 103.33 ? 200 GLU A C   1 
ATOM   1516 O O   . GLU A 1 200 ? 139.300 105.696 89.446  1.00 103.33 ? 200 GLU A O   1 
ATOM   1517 C CB  . GLU A 1 200 ? 140.493 108.642 90.527  1.00 103.33 ? 200 GLU A CB  1 
ATOM   1518 C CG  . GLU A 1 200 ? 141.937 108.090 90.356  1.00 103.33 ? 200 GLU A CG  1 
ATOM   1519 C CD  . GLU A 1 200 ? 142.103 106.574 90.436  1.00 103.33 ? 200 GLU A CD  1 
ATOM   1520 O OE1 . GLU A 1 200 ? 141.412 105.915 91.241  1.00 103.33 ? 200 GLU A OE1 1 
ATOM   1521 O OE2 . GLU A 1 200 ? 142.932 106.036 89.674  1.00 103.33 ? 200 GLU A OE2 1 
ATOM   1522 N N   . LEU A 1 201 ? 138.086 106.643 91.081  1.00 100.51 ? 201 LEU A N   1 
ATOM   1523 C CA  . LEU A 1 201 ? 137.487 105.384 91.497  1.00 100.51 ? 201 LEU A CA  1 
ATOM   1524 C C   . LEU A 1 201 ? 136.215 105.144 90.685  1.00 100.51 ? 201 LEU A C   1 
ATOM   1525 O O   . LEU A 1 201 ? 135.973 105.793 89.665  1.00 100.51 ? 201 LEU A O   1 
ATOM   1526 C CB  . LEU A 1 201 ? 137.231 105.383 93.003  1.00 100.51 ? 201 LEU A CB  1 
ATOM   1527 C CG  . LEU A 1 201 ? 138.492 105.345 93.871  1.00 100.51 ? 201 LEU A CG  1 
ATOM   1528 C CD1 . LEU A 1 201 ? 138.589 106.580 94.753  1.00 100.51 ? 201 LEU A CD1 1 
ATOM   1529 C CD2 . LEU A 1 201 ? 138.549 104.076 94.707  1.00 100.51 ? 201 LEU A CD2 1 
ATOM   1530 N N   . ASP A 1 202 ? 135.398 104.180 91.108  1.00 101.65 ? 202 ASP A N   1 
ATOM   1531 C CA  . ASP A 1 202 ? 134.137 103.893 90.435  1.00 101.65 ? 202 ASP A CA  1 
ATOM   1532 C C   . ASP A 1 202 ? 132.951 104.028 91.385  1.00 101.65 ? 202 ASP A C   1 
ATOM   1533 O O   . ASP A 1 202 ? 131.932 103.356 91.216  1.00 101.65 ? 202 ASP A O   1 
ATOM   1534 C CB  . ASP A 1 202 ? 134.160 102.505 89.797  1.00 101.65 ? 202 ASP A CB  1 
ATOM   1535 C CG  . ASP A 1 202 ? 134.816 101.470 90.680  1.00 101.65 ? 202 ASP A CG  1 
ATOM   1536 O OD1 . ASP A 1 202 ? 136.063 101.423 90.724  1.00 101.65 ? 202 ASP A OD1 1 
ATOM   1537 O OD2 . ASP A 1 202 ? 134.078 100.695 91.322  1.00 101.65 ? 202 ASP A OD2 1 
ATOM   1538 N N   . MET A 1 203 ? 133.071 104.892 92.397  1.00 99.13  ? 203 MET A N   1 
ATOM   1539 C CA  . MET A 1 203 ? 131.938 105.192 93.265  1.00 99.13  ? 203 MET A CA  1 
ATOM   1540 C C   . MET A 1 203 ? 130.876 106.040 92.580  1.00 99.13  ? 203 MET A C   1 
ATOM   1541 O O   . MET A 1 203 ? 129.789 106.206 93.144  1.00 99.13  ? 203 MET A O   1 
ATOM   1542 C CB  . MET A 1 203 ? 132.397 105.917 94.533  1.00 99.13  ? 203 MET A CB  1 
ATOM   1543 C CG  . MET A 1 203 ? 133.703 105.440 95.137  1.00 99.13  ? 203 MET A CG  1 
ATOM   1544 S SD  . MET A 1 203 ? 133.538 103.866 95.995  1.00 99.13  ? 203 MET A SD  1 
ATOM   1545 C CE  . MET A 1 203 ? 135.259 103.445 96.239  1.00 99.13  ? 203 MET A CE  1 
ATOM   1546 N N   . ILE A 1 204 ? 131.166 106.588 91.404  1.00 111.99 ? 204 ILE A N   1 
ATOM   1547 C CA  . ILE A 1 204 ? 130.214 107.482 90.735  1.00 111.99 ? 204 ILE A CA  1 
ATOM   1548 C C   . ILE A 1 204 ? 128.967 106.696 90.343  1.00 111.99 ? 204 ILE A C   1 
ATOM   1549 O O   . ILE A 1 204 ? 129.076 105.636 89.694  1.00 111.99 ? 204 ILE A O   1 
ATOM   1550 C CB  . ILE A 1 204 ? 130.870 108.144 89.507  1.00 111.99 ? 204 ILE A CB  1 
ATOM   1551 C CG1 . ILE A 1 204 ? 129.835 108.916 88.683  1.00 111.99 ? 204 ILE A CG1 1 
ATOM   1552 C CG2 . ILE A 1 204 ? 131.635 107.124 88.664  1.00 111.99 ? 204 ILE A CG2 1 
ATOM   1553 C CD1 . ILE A 1 204 ? 129.488 110.270 89.259  1.00 111.99 ? 204 ILE A CD1 1 
ATOM   1554 N N   . PRO A 1 205 ? 127.772 107.134 90.735  1.00 119.74 ? 205 PRO A N   1 
ATOM   1555 C CA  . PRO A 1 205 ? 126.559 106.398 90.365  1.00 119.74 ? 205 PRO A CA  1 
ATOM   1556 C C   . PRO A 1 205 ? 126.298 106.452 88.868  1.00 119.74 ? 205 PRO A C   1 
ATOM   1557 O O   . PRO A 1 205 ? 126.624 107.429 88.188  1.00 119.74 ? 205 PRO A O   1 
ATOM   1558 C CB  . PRO A 1 205 ? 125.454 107.118 91.147  1.00 119.74 ? 205 PRO A CB  1 
ATOM   1559 C CG  . PRO A 1 205 ? 126.003 108.479 91.412  1.00 119.74 ? 205 PRO A CG  1 
ATOM   1560 C CD  . PRO A 1 205 ? 127.477 108.289 91.598  1.00 119.74 ? 205 PRO A CD  1 
ATOM   1561 N N   . VAL A 1 206 ? 125.697 105.382 88.361  1.00 138.43 ? 206 VAL A N   1 
ATOM   1562 C CA  . VAL A 1 206 ? 125.353 105.249 86.953  1.00 138.43 ? 206 VAL A CA  1 
ATOM   1563 C C   . VAL A 1 206 ? 123.837 105.131 86.852  1.00 138.43 ? 206 VAL A C   1 
ATOM   1564 O O   . VAL A 1 206 ? 123.250 104.218 87.440  1.00 138.43 ? 206 VAL A O   1 
ATOM   1565 C CB  . VAL A 1 206 ? 126.036 104.035 86.301  1.00 138.43 ? 206 VAL A CB  1 
ATOM   1566 C CG1 . VAL A 1 206 ? 125.691 103.965 84.821  1.00 138.43 ? 206 VAL A CG1 1 
ATOM   1567 C CG2 . VAL A 1 206 ? 127.541 104.103 86.501  1.00 138.43 ? 206 VAL A CG2 1 
ATOM   1568 N N   . PRO A 1 207 ? 123.159 106.029 86.140  1.00 147.85 ? 207 PRO A N   1 
ATOM   1569 C CA  . PRO A 1 207 ? 121.705 105.911 85.996  1.00 147.85 ? 207 PRO A CA  1 
ATOM   1570 C C   . PRO A 1 207 ? 121.320 104.669 85.209  1.00 147.85 ? 207 PRO A C   1 
ATOM   1571 O O   . PRO A 1 207 ? 122.053 104.203 84.334  1.00 147.85 ? 207 PRO A O   1 
ATOM   1572 C CB  . PRO A 1 207 ? 121.317 107.188 85.243  1.00 147.85 ? 207 PRO A CB  1 
ATOM   1573 C CG  . PRO A 1 207 ? 122.562 107.590 84.526  1.00 147.85 ? 207 PRO A CG  1 
ATOM   1574 C CD  . PRO A 1 207 ? 123.692 107.205 85.432  1.00 147.85 ? 207 PRO A CD  1 
ATOM   1575 N N   . VAL A 1 208 ? 120.148 104.132 85.536  1.00 149.56 ? 208 VAL A N   1 
ATOM   1576 C CA  . VAL A 1 208 ? 119.630 102.920 84.914  1.00 149.56 ? 208 VAL A CA  1 
ATOM   1577 C C   . VAL A 1 208 ? 118.327 103.259 84.206  1.00 149.56 ? 208 VAL A C   1 
ATOM   1578 O O   . VAL A 1 208 ? 117.461 103.937 84.772  1.00 149.56 ? 208 VAL A O   1 
ATOM   1579 C CB  . VAL A 1 208 ? 119.426 101.792 85.943  1.00 149.56 ? 208 VAL A CB  1 
ATOM   1580 C CG1 . VAL A 1 208 ? 120.762 101.166 86.310  1.00 149.56 ? 208 VAL A CG1 1 
ATOM   1581 C CG2 . VAL A 1 208 ? 118.732 102.321 87.191  1.00 149.56 ? 208 VAL A CG2 1 
ATOM   1582 N N   . ILE A 1 209 ? 118.199 102.805 82.963  1.00 138.27 ? 209 ILE A N   1 
ATOM   1583 C CA  . ILE A 1 209 ? 116.995 103.004 82.166  1.00 138.27 ? 209 ILE A CA  1 
ATOM   1584 C C   . ILE A 1 209 ? 116.106 101.778 82.320  1.00 138.27 ? 209 ILE A C   1 
ATOM   1585 O O   . ILE A 1 209 ? 116.574 100.639 82.198  1.00 138.27 ? 209 ILE A O   1 
ATOM   1586 C CB  . ILE A 1 209 ? 117.338 103.276 80.689  1.00 138.27 ? 209 ILE A CB  1 
ATOM   1587 C CG1 . ILE A 1 209 ? 116.065 103.360 79.844  1.00 138.27 ? 209 ILE A CG1 1 
ATOM   1588 C CG2 . ILE A 1 209 ? 118.323 102.243 80.145  1.00 138.27 ? 209 ILE A CG2 1 
ATOM   1589 C CD1 . ILE A 1 209 ? 116.313 103.760 78.408  1.00 138.27 ? 209 ILE A CD1 1 
ATOM   1590 N N   . VAL A 1 210 ? 114.829 102.007 82.615  1.00 130.62 ? 210 VAL A N   1 
ATOM   1591 C CA  . VAL A 1 210 ? 113.861 100.941 82.836  1.00 130.62 ? 210 VAL A CA  1 
ATOM   1592 C C   . VAL A 1 210 ? 112.939 100.865 81.628  1.00 130.62 ? 210 VAL A C   1 
ATOM   1593 O O   . VAL A 1 210 ? 112.432 101.891 81.156  1.00 130.62 ? 210 VAL A O   1 
ATOM   1594 C CB  . VAL A 1 210 ? 113.072 101.155 84.143  1.00 130.62 ? 210 VAL A CB  1 
ATOM   1595 C CG1 . VAL A 1 210 ? 112.494 102.565 84.214  1.00 130.62 ? 210 VAL A CG1 1 
ATOM   1596 C CG2 . VAL A 1 210 ? 111.974 100.111 84.287  1.00 130.62 ? 210 VAL A CG2 1 
ATOM   1597 N N   . ALA A 1 211 ? 112.752 99.657  81.107  1.00 118.17 ? 211 ALA A N   1 
ATOM   1598 C CA  . ALA A 1 211 ? 111.850 99.461  79.984  1.00 118.17 ? 211 ALA A CA  1 
ATOM   1599 C C   . ALA A 1 211 ? 110.407 99.686  80.415  1.00 118.17 ? 211 ALA A C   1 
ATOM   1600 O O   . ALA A 1 211 ? 110.040 99.488  81.576  1.00 118.17 ? 211 ALA A O   1 
ATOM   1601 C CB  . ALA A 1 211 ? 112.013 98.057  79.402  1.00 118.17 ? 211 ALA A CB  1 
ATOM   1602 N N   . SER A 1 212 ? 109.584 100.110 79.460  1.00 116.03 ? 212 SER A N   1 
ATOM   1603 C CA  . SER A 1 212 ? 108.181 100.378 79.728  1.00 116.03 ? 212 SER A CA  1 
ATOM   1604 C C   . SER A 1 212 ? 107.361 99.942  78.525  1.00 116.03 ? 212 SER A C   1 
ATOM   1605 O O   . SER A 1 212 ? 107.892 99.719  77.435  1.00 116.03 ? 212 SER A O   1 
ATOM   1606 C CB  . SER A 1 212 ? 107.935 101.859 80.038  1.00 116.03 ? 212 SER A CB  1 
ATOM   1607 O OG  . SER A 1 212 ? 106.559 102.177 79.933  1.00 116.03 ? 212 SER A OG  1 
ATOM   1608 N N   . THR A 1 213 ? 106.056 99.817  78.739  1.00 118.44 ? 213 THR A N   1 
ATOM   1609 C CA  . THR A 1 213 ? 105.126 99.398  77.699  1.00 118.44 ? 213 THR A CA  1 
ATOM   1610 C C   . THR A 1 213 ? 104.481 100.641 77.100  1.00 118.44 ? 213 THR A C   1 
ATOM   1611 O O   . THR A 1 213 ? 103.719 101.340 77.776  1.00 118.44 ? 213 THR A O   1 
ATOM   1612 C CB  . THR A 1 213 ? 104.070 98.453  78.265  1.00 118.44 ? 213 THR A CB  1 
ATOM   1613 O OG1 . THR A 1 213 ? 103.729 98.860  79.596  1.00 118.44 ? 213 THR A OG1 1 
ATOM   1614 C CG2 . THR A 1 213 ? 104.599 97.030  78.298  1.00 118.44 ? 213 THR A CG2 1 
ATOM   1615 N N   . HIS A 1 214 ? 104.790 100.919 75.837  1.00 118.70 ? 214 HIS A N   1 
ATOM   1616 C CA  . HIS A 1 214 ? 104.221 102.048 75.116  1.00 118.70 ? 214 HIS A CA  1 
ATOM   1617 C C   . HIS A 1 214 ? 103.220 101.530 74.094  1.00 118.70 ? 214 HIS A C   1 
ATOM   1618 O O   . HIS A 1 214 ? 103.544 100.649 73.290  1.00 118.70 ? 214 HIS A O   1 
ATOM   1619 C CB  . HIS A 1 214 ? 105.312 102.870 74.429  1.00 118.70 ? 214 HIS A CB  1 
ATOM   1620 C CG  . HIS A 1 214 ? 106.226 103.579 75.377  1.00 118.70 ? 214 HIS A CG  1 
ATOM   1621 N ND1 . HIS A 1 214 ? 107.277 104.362 74.951  1.00 118.70 ? 214 HIS A ND1 1 
ATOM   1622 C CD2 . HIS A 1 214 ? 106.245 103.629 76.730  1.00 118.70 ? 214 HIS A CD2 1 
ATOM   1623 C CE1 . HIS A 1 214 ? 107.905 104.862 75.999  1.00 118.70 ? 214 HIS A CE1 1 
ATOM   1624 N NE2 . HIS A 1 214 ? 107.299 104.433 77.091  1.00 118.70 ? 214 HIS A NE2 1 
ATOM   1625 N N   . PHE A 1 215 ? 102.008 102.080 74.126  1.00 125.77 ? 215 PHE A N   1 
ATOM   1626 C CA  . PHE A 1 215 ? 100.896 101.578 73.321  1.00 125.77 ? 215 PHE A CA  1 
ATOM   1627 C C   . PHE A 1 215 ? 100.867 102.320 71.991  1.00 125.77 ? 215 PHE A C   1 
ATOM   1628 O O   . PHE A 1 215 ? 100.173 103.325 71.828  1.00 125.77 ? 215 PHE A O   1 
ATOM   1629 C CB  . PHE A 1 215 ? 99.582  101.736 74.074  1.00 125.77 ? 215 PHE A CB  1 
ATOM   1630 C CG  . PHE A 1 215 ? 99.633  101.236 75.488  1.00 125.77 ? 215 PHE A CG  1 
ATOM   1631 C CD1 . PHE A 1 215 ? 99.568  99.881  75.762  1.00 125.77 ? 215 PHE A CD1 1 
ATOM   1632 C CD2 . PHE A 1 215 ? 99.749  102.124 76.543  1.00 125.77 ? 215 PHE A CD2 1 
ATOM   1633 C CE1 . PHE A 1 215 ? 99.616  99.421  77.063  1.00 125.77 ? 215 PHE A CE1 1 
ATOM   1634 C CE2 . PHE A 1 215 ? 99.798  101.671 77.845  1.00 125.77 ? 215 PHE A CE2 1 
ATOM   1635 C CZ  . PHE A 1 215 ? 99.731  100.319 78.106  1.00 125.77 ? 215 PHE A CZ  1 
ATOM   1636 N N   . TYR A 1 216 ? 101.631 101.820 71.024  1.00 137.55 ? 216 TYR A N   1 
ATOM   1637 C CA  . TYR A 1 216 ? 101.565 102.349 69.670  1.00 137.55 ? 216 TYR A CA  1 
ATOM   1638 C C   . TYR A 1 216 ? 100.445 101.667 68.895  1.00 137.55 ? 216 TYR A C   1 
ATOM   1639 O O   . TYR A 1 216 ? 100.398 100.436 68.808  1.00 137.55 ? 216 TYR A O   1 
ATOM   1640 C CB  . TYR A 1 216 ? 102.891 102.155 68.935  1.00 137.55 ? 216 TYR A CB  1 
ATOM   1641 C CG  . TYR A 1 216 ? 104.045 102.980 69.454  1.00 137.55 ? 216 TYR A CG  1 
ATOM   1642 C CD1 . TYR A 1 216 ? 104.736 102.610 70.598  1.00 137.55 ? 216 TYR A CD1 1 
ATOM   1643 C CD2 . TYR A 1 216 ? 104.440 104.138 68.797  1.00 137.55 ? 216 TYR A CD2 1 
ATOM   1644 C CE1 . TYR A 1 216 ? 105.794 103.364 71.064  1.00 137.55 ? 216 TYR A CE1 1 
ATOM   1645 C CE2 . TYR A 1 216 ? 105.492 104.901 69.261  1.00 137.55 ? 216 TYR A CE2 1 
ATOM   1646 C CZ  . TYR A 1 216 ? 106.165 104.509 70.395  1.00 137.55 ? 216 TYR A CZ  1 
ATOM   1647 O OH  . TYR A 1 216 ? 107.216 105.263 70.864  1.00 137.55 ? 216 TYR A OH  1 
ATOM   1648 N N   . THR A 1 217 ? 99.559  102.469 68.318  1.00 149.88 ? 217 THR A N   1 
ATOM   1649 C CA  . THR A 1 217 ? 98.479  101.975 67.480  1.00 149.88 ? 217 THR A CA  1 
ATOM   1650 C C   . THR A 1 217 ? 98.851  102.103 66.005  1.00 149.88 ? 217 THR A C   1 
ATOM   1651 O O   . THR A 1 217 ? 99.768  102.839 65.626  1.00 149.88 ? 217 THR A O   1 
ATOM   1652 C CB  . THR A 1 217 ? 97.168  102.713 67.778  1.00 149.88 ? 217 THR A CB  1 
ATOM   1653 O OG1 . THR A 1 217 ? 96.059  101.867 67.454  1.00 149.88 ? 217 THR A OG1 1 
ATOM   1654 C CG2 . THR A 1 217 ? 97.060  103.994 66.975  1.00 149.88 ? 217 THR A CG2 1 
ATOM   1655 N N   . ILE A 1 218 ? 98.114  101.371 65.174  1.00 159.29 ? 218 ILE A N   1 
ATOM   1656 C CA  . ILE A 1 218 ? 98.492  101.090 63.793  1.00 159.29 ? 218 ILE A CA  1 
ATOM   1657 C C   . ILE A 1 218 ? 97.988  102.189 62.868  1.00 159.29 ? 218 ILE A C   1 
ATOM   1658 O O   . ILE A 1 218 ? 96.860  102.676 63.007  1.00 159.29 ? 218 ILE A O   1 
ATOM   1659 C CB  . ILE A 1 218 ? 97.956  99.706  63.372  1.00 159.29 ? 218 ILE A CB  1 
ATOM   1660 C CG1 . ILE A 1 218 ? 98.916  98.610  63.830  1.00 159.29 ? 218 ILE A CG1 1 
ATOM   1661 C CG2 . ILE A 1 218 ? 97.706  99.621  61.868  1.00 159.29 ? 218 ILE A CG2 1 
ATOM   1662 C CD1 . ILE A 1 218 ? 100.147 98.488  62.975  1.00 159.29 ? 218 ILE A CD1 1 
ATOM   1663 N N   . ASN A 1 219 ? 98.838  102.590 61.923  1.00 169.47 ? 219 ASN A N   1 
ATOM   1664 C CA  . ASN A 1 219 ? 98.411  103.424 60.807  1.00 169.47 ? 219 ASN A CA  1 
ATOM   1665 C C   . ASN A 1 219 ? 97.755  102.530 59.761  1.00 169.47 ? 219 ASN A C   1 
ATOM   1666 O O   . ASN A 1 219 ? 98.362  101.556 59.302  1.00 169.47 ? 219 ASN A O   1 
ATOM   1667 C CB  . ASN A 1 219 ? 99.605  104.174 60.217  1.00 169.47 ? 219 ASN A CB  1 
ATOM   1668 C CG  . ASN A 1 219 ? 99.358  104.659 58.797  1.00 169.47 ? 219 ASN A CG  1 
ATOM   1669 O OD1 . ASN A 1 219 ? 98.271  105.134 58.464  1.00 169.47 ? 219 ASN A OD1 1 
ATOM   1670 N ND2 . ASN A 1 219 ? 100.373 104.533 57.950  1.00 169.47 ? 219 ASN A ND2 1 
ATOM   1671 N N   . ASP A 1 220 ? 96.518  102.853 59.393  1.00 175.09 ? 220 ASP A N   1 
ATOM   1672 C CA  . ASP A 1 220 ? 95.782  102.036 58.438  1.00 175.09 ? 220 ASP A CA  1 
ATOM   1673 C C   . ASP A 1 220 ? 96.426  102.119 57.059  1.00 175.09 ? 220 ASP A C   1 
ATOM   1674 O O   . ASP A 1 220 ? 96.846  103.191 56.613  1.00 175.09 ? 220 ASP A O   1 
ATOM   1675 C CB  . ASP A 1 220 ? 94.320  102.487 58.376  1.00 175.09 ? 220 ASP A CB  1 
ATOM   1676 C CG  . ASP A 1 220 ? 93.454  101.571 57.524  1.00 175.09 ? 220 ASP A CG  1 
ATOM   1677 O OD1 . ASP A 1 220 ? 93.612  101.564 56.285  1.00 175.09 ? 220 ASP A OD1 1 
ATOM   1678 O OD2 . ASP A 1 220 ? 92.609  100.855 58.101  1.00 175.09 ? 220 ASP A OD2 1 
ATOM   1679 N N   . GLY A 1 221 ? 96.496  100.978 56.382  1.00 175.36 ? 221 GLY A N   1 
ATOM   1680 C CA  . GLY A 1 221 ? 97.108  100.913 55.065  1.00 175.36 ? 221 GLY A CA  1 
ATOM   1681 C C   . GLY A 1 221 ? 98.598  101.175 55.052  1.00 175.36 ? 221 GLY A C   1 
ATOM   1682 O O   . GLY A 1 221 ? 99.090  101.891 54.169  1.00 175.36 ? 221 GLY A O   1 
ATOM   1683 N N   . SER A 1 222 ? 99.333  100.611 56.008  1.00 174.98 ? 222 SER A N   1 
ATOM   1684 C CA  . SER A 1 222 ? 100.775 100.795 56.107  1.00 174.98 ? 222 SER A CA  1 
ATOM   1685 C C   . SER A 1 222 ? 101.565 99.717  55.377  1.00 174.98 ? 222 SER A C   1 
ATOM   1686 O O   . SER A 1 222 ? 102.795 99.687  55.503  1.00 174.98 ? 222 SER A O   1 
ATOM   1687 C CB  . SER A 1 222 ? 101.199 100.836 57.578  1.00 174.98 ? 222 SER A CB  1 
ATOM   1688 O OG  . SER A 1 222 ? 100.935 99.598  58.217  1.00 174.98 ? 222 SER A OG  1 
ATOM   1689 N N   . SER A 1 223 ? 100.881 98.809  54.670  1.00 177.82 ? 223 SER A N   1 
ATOM   1690 C CA  . SER A 1 223 ? 101.462 97.750  53.843  1.00 177.82 ? 223 SER A CA  1 
ATOM   1691 C C   . SER A 1 223 ? 102.116 96.652  54.678  1.00 177.82 ? 223 SER A C   1 
ATOM   1692 O O   . SER A 1 223 ? 102.567 95.640  54.131  1.00 177.82 ? 223 SER A O   1 
ATOM   1693 C CB  . SER A 1 223 ? 102.467 98.319  52.833  1.00 177.82 ? 223 SER A CB  1 
ATOM   1694 O OG  . SER A 1 223 ? 103.747 98.475  53.419  1.00 177.82 ? 223 SER A OG  1 
ATOM   1695 N N   . LEU A 1 224 ? 102.174 96.834  55.995  1.00 169.85 ? 224 LEU A N   1 
ATOM   1696 C CA  . LEU A 1 224 ? 102.615 95.790  56.909  1.00 169.85 ? 224 LEU A CA  1 
ATOM   1697 C C   . LEU A 1 224 ? 101.450 95.074  57.575  1.00 169.85 ? 224 LEU A C   1 
ATOM   1698 O O   . LEU A 1 224 ? 101.673 94.192  58.409  1.00 169.85 ? 224 LEU A O   1 
ATOM   1699 C CB  . LEU A 1 224 ? 103.548 96.370  57.979  1.00 169.85 ? 224 LEU A CB  1 
ATOM   1700 C CG  . LEU A 1 224 ? 105.054 96.303  57.702  1.00 169.85 ? 224 LEU A CG  1 
ATOM   1701 C CD1 . LEU A 1 224 ? 105.436 97.091  56.455  1.00 169.85 ? 224 LEU A CD1 1 
ATOM   1702 C CD2 . LEU A 1 224 ? 105.849 96.777  58.909  1.00 169.85 ? 224 LEU A CD2 1 
ATOM   1703 N N   . ILE A 1 225 ? 100.216 95.438  57.227  1.00 173.48 ? 225 ILE A N   1 
ATOM   1704 C CA  . ILE A 1 225 ? 99.041  94.803  57.808  1.00 173.48 ? 225 ILE A CA  1 
ATOM   1705 C C   . ILE A 1 225 ? 98.863  93.418  57.202  1.00 173.48 ? 225 ILE A C   1 
ATOM   1706 O O   . ILE A 1 225 ? 98.834  93.258  55.975  1.00 173.48 ? 225 ILE A O   1 
ATOM   1707 C CB  . ILE A 1 225 ? 97.801  95.682  57.583  1.00 173.48 ? 225 ILE A CB  1 
ATOM   1708 C CG1 . ILE A 1 225 ? 97.815  96.880  58.537  1.00 173.48 ? 225 ILE A CG1 1 
ATOM   1709 C CG2 . ILE A 1 225 ? 96.523  94.873  57.732  1.00 173.48 ? 225 ILE A CG2 1 
ATOM   1710 C CD1 . ILE A 1 225 ? 96.601  97.776  58.414  1.00 173.48 ? 225 ILE A CD1 1 
ATOM   1711 N N   . GLY A 1 226 ? 98.746  92.408  58.061  1.00 168.88 ? 226 GLY A N   1 
ATOM   1712 C CA  . GLY A 1 226 ? 98.529  91.050  57.602  1.00 168.88 ? 226 GLY A CA  1 
ATOM   1713 C C   . GLY A 1 226 ? 99.692  90.112  57.855  1.00 168.88 ? 226 GLY A C   1 
ATOM   1714 O O   . GLY A 1 226 ? 99.906  89.163  57.094  1.00 168.88 ? 226 GLY A O   1 
ATOM   1715 N N   . GLN A 1 227 ? 100.451 90.363  58.918  1.00 163.22 ? 227 GLN A N   1 
ATOM   1716 C CA  . GLN A 1 227 ? 101.577 89.523  59.301  1.00 163.22 ? 227 GLN A CA  1 
ATOM   1717 C C   . GLN A 1 227 ? 101.357 89.005  60.716  1.00 163.22 ? 227 GLN A C   1 
ATOM   1718 O O   . GLN A 1 227 ? 100.874 89.738  61.585  1.00 163.22 ? 227 GLN A O   1 
ATOM   1719 C CB  . GLN A 1 227 ? 102.898 90.294  59.212  1.00 163.22 ? 227 GLN A CB  1 
ATOM   1720 C CG  . GLN A 1 227 ? 104.138 89.416  59.256  1.00 163.22 ? 227 GLN A CG  1 
ATOM   1721 C CD  . GLN A 1 227 ? 105.422 90.223  59.282  1.00 163.22 ? 227 GLN A CD  1 
ATOM   1722 O OE1 . GLN A 1 227 ? 105.674 91.036  58.393  1.00 163.22 ? 227 GLN A OE1 1 
ATOM   1723 N NE2 . GLN A 1 227 ? 106.244 89.996  60.298  1.00 163.22 ? 227 GLN A NE2 1 
ATOM   1724 N N   . THR A 1 228 ? 101.700 87.737  60.940  1.00 159.01 ? 228 THR A N   1 
ATOM   1725 C CA  . THR A 1 228 ? 101.430 87.112  62.227  1.00 159.01 ? 228 THR A CA  1 
ATOM   1726 C C   . THR A 1 228 ? 102.308 87.713  63.323  1.00 159.01 ? 228 THR A C   1 
ATOM   1727 O O   . THR A 1 228 ? 103.422 88.193  63.077  1.00 159.01 ? 228 THR A O   1 
ATOM   1728 C CB  . THR A 1 228 ? 101.620 85.592  62.140  1.00 159.01 ? 228 THR A CB  1 
ATOM   1729 O OG1 . THR A 1 228 ? 100.817 84.952  63.141  1.00 159.01 ? 228 THR A OG1 1 
ATOM   1730 C CG2 . THR A 1 228 ? 103.073 85.192  62.337  1.00 159.01 ? 228 THR A CG2 1 
ATOM   1731 N N   . LEU A 1 229 ? 101.775 87.696  64.549  1.00 152.66 ? 229 LEU A N   1 
ATOM   1732 C CA  . LEU A 1 229 ? 102.415 88.396  65.658  1.00 152.66 ? 229 LEU A CA  1 
ATOM   1733 C C   . LEU A 1 229 ? 103.760 87.785  66.021  1.00 152.66 ? 229 LEU A C   1 
ATOM   1734 O O   . LEU A 1 229 ? 104.678 88.513  66.409  1.00 152.66 ? 229 LEU A O   1 
ATOM   1735 C CB  . LEU A 1 229 ? 101.492 88.404  66.877  1.00 152.66 ? 229 LEU A CB  1 
ATOM   1736 C CG  . LEU A 1 229 ? 100.481 89.550  66.961  1.00 152.66 ? 229 LEU A CG  1 
ATOM   1737 C CD1 . LEU A 1 229 ? 99.885  89.638  68.357  1.00 152.66 ? 229 LEU A CD1 1 
ATOM   1738 C CD2 . LEU A 1 229 ? 101.120 90.872  66.562  1.00 152.66 ? 229 LEU A CD2 1 
ATOM   1739 N N   . GLY A 1 230 ? 103.901 86.463  65.903  1.00 152.08 ? 230 GLY A N   1 
ATOM   1740 C CA  . GLY A 1 230 ? 105.185 85.842  66.192  1.00 152.08 ? 230 GLY A CA  1 
ATOM   1741 C C   . GLY A 1 230 ? 106.272 86.288  65.233  1.00 152.08 ? 230 GLY A C   1 
ATOM   1742 O O   . GLY A 1 230 ? 107.388 86.618  65.645  1.00 152.08 ? 230 GLY A O   1 
ATOM   1743 N N   . THR A 1 231 ? 105.955 86.315  63.936  1.00 152.86 ? 231 THR A N   1 
ATOM   1744 C CA  . THR A 1 231 ? 106.925 86.786  62.954  1.00 152.86 ? 231 THR A CA  1 
ATOM   1745 C C   . THR A 1 231 ? 107.216 88.271  63.127  1.00 152.86 ? 231 THR A C   1 
ATOM   1746 O O   . THR A 1 231 ? 108.359 88.698  62.939  1.00 152.86 ? 231 THR A O   1 
ATOM   1747 C CB  . THR A 1 231 ? 106.430 86.492  61.536  1.00 152.86 ? 231 THR A CB  1 
ATOM   1748 O OG1 . THR A 1 231 ? 106.155 85.092  61.408  1.00 152.86 ? 231 THR A OG1 1 
ATOM   1749 C CG2 . THR A 1 231 ? 107.481 86.876  60.506  1.00 152.86 ? 231 THR A CG2 1 
ATOM   1750 N N   . VAL A 1 232 ? 106.215 89.068  63.514  1.00 150.60 ? 232 VAL A N   1 
ATOM   1751 C CA  . VAL A 1 232 ? 106.472 90.480  63.792  1.00 150.60 ? 232 VAL A CA  1 
ATOM   1752 C C   . VAL A 1 232 ? 107.411 90.634  64.989  1.00 150.60 ? 232 VAL A C   1 
ATOM   1753 O O   . VAL A 1 232 ? 108.332 91.464  64.974  1.00 150.60 ? 232 VAL A O   1 
ATOM   1754 C CB  . VAL A 1 232 ? 105.146 91.234  64.001  1.00 150.60 ? 232 VAL A CB  1 
ATOM   1755 C CG1 . VAL A 1 232 ? 105.409 92.671  64.374  1.00 150.60 ? 232 VAL A CG1 1 
ATOM   1756 C CG2 . VAL A 1 232 ? 104.307 91.190  62.738  1.00 150.60 ? 232 VAL A CG2 1 
ATOM   1757 N N   . ASN A 1 233 ? 107.199 89.835  66.039  1.00 144.06 ? 233 ASN A N   1 
ATOM   1758 C CA  . ASN A 1 233 ? 108.070 89.891  67.209  1.00 144.06 ? 233 ASN A CA  1 
ATOM   1759 C C   . ASN A 1 233 ? 109.497 89.483  66.862  1.00 144.06 ? 233 ASN A C   1 
ATOM   1760 O O   . ASN A 1 233 ? 110.458 90.091  67.348  1.00 144.06 ? 233 ASN A O   1 
ATOM   1761 C CB  . ASN A 1 233 ? 107.514 89.007  68.326  1.00 144.06 ? 233 ASN A CB  1 
ATOM   1762 C CG  . ASN A 1 233 ? 106.185 89.508  68.857  1.00 144.06 ? 233 ASN A CG  1 
ATOM   1763 O OD1 . ASN A 1 233 ? 105.655 90.513  68.386  1.00 144.06 ? 233 ASN A OD1 1 
ATOM   1764 N ND2 . ASN A 1 233 ? 105.642 88.809  69.847  1.00 144.06 ? 233 ASN A ND2 1 
ATOM   1765 N N   . THR A 1 234 ? 109.659 88.446  66.035  1.00 148.65 ? 234 THR A N   1 
ATOM   1766 C CA  . THR A 1 234 ? 110.999 88.094  65.571  1.00 148.65 ? 234 THR A CA  1 
ATOM   1767 C C   . THR A 1 234 ? 111.587 89.179  64.675  1.00 148.65 ? 234 THR A C   1 
ATOM   1768 O O   . THR A 1 234 ? 112.810 89.355  64.640  1.00 148.65 ? 234 THR A O   1 
ATOM   1769 C CB  . THR A 1 234 ? 110.986 86.752  64.835  1.00 148.65 ? 234 THR A CB  1 
ATOM   1770 O OG1 . THR A 1 234 ? 110.223 86.868  63.627  1.00 148.65 ? 234 THR A OG1 1 
ATOM   1771 C CG2 . THR A 1 234 ? 110.409 85.654  65.716  1.00 148.65 ? 234 THR A CG2 1 
ATOM   1772 N N   . LYS A 1 235 ? 110.738 89.906  63.944  1.00 150.42 ? 235 LYS A N   1 
ATOM   1773 C CA  . LYS A 1 235 ? 111.207 91.035  63.149  1.00 150.42 ? 235 LYS A CA  1 
ATOM   1774 C C   . LYS A 1 235 ? 111.742 92.153  64.032  1.00 150.42 ? 235 LYS A C   1 
ATOM   1775 O O   . LYS A 1 235 ? 112.699 92.838  63.650  1.00 150.42 ? 235 LYS A O   1 
ATOM   1776 C CB  . LYS A 1 235 ? 110.078 91.557  62.258  1.00 150.42 ? 235 LYS A CB  1 
ATOM   1777 C CG  . LYS A 1 235 ? 110.478 92.703  61.343  1.00 150.42 ? 235 LYS A CG  1 
ATOM   1778 C CD  . LYS A 1 235 ? 109.379 93.032  60.345  1.00 150.42 ? 235 LYS A CD  1 
ATOM   1779 C CE  . LYS A 1 235 ? 108.035 93.206  61.037  1.00 150.42 ? 235 LYS A CE  1 
ATOM   1780 N NZ  . LYS A 1 235 ? 106.920 93.344  60.060  1.00 150.42 ? 235 LYS A NZ  1 
ATOM   1781 N N   . PHE A 1 236 ? 111.138 92.355  65.202  1.00 139.56 ? 236 PHE A N   1 
ATOM   1782 C CA  . PHE A 1 236 ? 111.659 93.331  66.151  1.00 139.56 ? 236 PHE A CA  1 
ATOM   1783 C C   . PHE A 1 236 ? 113.080 92.976  66.575  1.00 139.56 ? 236 PHE A C   1 
ATOM   1784 O O   . PHE A 1 236 ? 113.443 91.804  66.702  1.00 139.56 ? 236 PHE A O   1 
ATOM   1785 C CB  . PHE A 1 236 ? 110.761 93.420  67.385  1.00 139.56 ? 236 PHE A CB  1 
ATOM   1786 C CG  . PHE A 1 236 ? 109.382 93.925  67.098  1.00 139.56 ? 236 PHE A CG  1 
ATOM   1787 C CD1 . PHE A 1 236 ? 109.173 94.888  66.126  1.00 139.56 ? 236 PHE A CD1 1 
ATOM   1788 C CD2 . PHE A 1 236 ? 108.294 93.444  67.805  1.00 139.56 ? 236 PHE A CD2 1 
ATOM   1789 C CE1 . PHE A 1 236 ? 107.905 95.362  65.863  1.00 139.56 ? 236 PHE A CE1 1 
ATOM   1790 C CE2 . PHE A 1 236 ? 107.022 93.908  67.543  1.00 139.56 ? 236 PHE A CE2 1 
ATOM   1791 C CZ  . PHE A 1 236 ? 106.829 94.876  66.577  1.00 139.56 ? 236 PHE A CZ  1 
ATOM   1792 N N   . ALA A 1 237 ? 113.887 94.013  66.789  1.00 131.09 ? 237 ALA A N   1 
ATOM   1793 C CA  . ALA A 1 237 ? 115.272 93.838  67.193  1.00 131.09 ? 237 ALA A CA  1 
ATOM   1794 C C   . ALA A 1 237 ? 115.355 93.208  68.584  1.00 131.09 ? 237 ALA A C   1 
ATOM   1795 O O   . ALA A 1 237 ? 114.356 93.046  69.290  1.00 131.09 ? 237 ALA A O   1 
ATOM   1796 C CB  . ALA A 1 237 ? 116.008 95.177  67.172  1.00 131.09 ? 237 ALA A CB  1 
ATOM   1797 N N   . LYS A 1 238 ? 116.577 92.842  68.966  1.00 124.03 ? 238 LYS A N   1 
ATOM   1798 C CA  . LYS A 1 238 ? 116.805 92.206  70.258  1.00 124.03 ? 238 LYS A CA  1 
ATOM   1799 C C   . LYS A 1 238 ? 116.431 93.152  71.392  1.00 124.03 ? 238 LYS A C   1 
ATOM   1800 O O   . LYS A 1 238 ? 116.868 94.306  71.427  1.00 124.03 ? 238 LYS A O   1 
ATOM   1801 C CB  . LYS A 1 238 ? 118.269 91.783  70.383  1.00 124.03 ? 238 LYS A CB  1 
ATOM   1802 C CG  . LYS A 1 238 ? 118.840 91.134  69.131  1.00 124.03 ? 238 LYS A CG  1 
ATOM   1803 C CD  . LYS A 1 238 ? 118.062 89.887  68.740  1.00 124.03 ? 238 LYS A CD  1 
ATOM   1804 C CE  . LYS A 1 238 ? 117.975 89.746  67.228  1.00 124.03 ? 238 LYS A CE  1 
ATOM   1805 N NZ  . LYS A 1 238 ? 117.269 90.899  66.602  1.00 124.03 ? 238 LYS A NZ  1 
ATOM   1806 N N   . GLY A 1 239 ? 115.622 92.657  72.323  1.00 124.63 ? 239 GLY A N   1 
ATOM   1807 C CA  . GLY A 1 239 ? 115.138 93.458  73.425  1.00 124.63 ? 239 GLY A CA  1 
ATOM   1808 C C   . GLY A 1 239 ? 113.757 94.047  73.247  1.00 124.63 ? 239 GLY A C   1 
ATOM   1809 O O   . GLY A 1 239 ? 113.336 94.849  74.088  1.00 124.63 ? 239 GLY A O   1 
ATOM   1810 N N   . LEU A 1 240 ? 113.040 93.680  72.188  1.00 124.98 ? 240 LEU A N   1 
ATOM   1811 C CA  . LEU A 1 240 ? 111.707 94.196  71.923  1.00 124.98 ? 240 LEU A CA  1 
ATOM   1812 C C   . LEU A 1 240 ? 110.701 93.059  71.895  1.00 124.98 ? 240 LEU A C   1 
ATOM   1813 O O   . LEU A 1 240 ? 111.033 91.925  71.536  1.00 124.98 ? 240 LEU A O   1 
ATOM   1814 C CB  . LEU A 1 240 ? 111.624 94.931  70.585  1.00 124.98 ? 240 LEU A CB  1 
ATOM   1815 C CG  . LEU A 1 240 ? 111.937 96.419  70.541  1.00 124.98 ? 240 LEU A CG  1 
ATOM   1816 C CD1 . LEU A 1 240 ? 113.418 96.614  70.691  1.00 124.98 ? 240 LEU A CD1 1 
ATOM   1817 C CD2 . LEU A 1 240 ? 111.440 97.019  69.247  1.00 124.98 ? 240 LEU A CD2 1 
ATOM   1818 N N   . VAL A 1 241 ? 109.460 93.380  72.261  1.00 128.80 ? 241 VAL A N   1 
ATOM   1819 C CA  . VAL A 1 241 ? 108.346 92.466  72.052  1.00 128.80 ? 241 VAL A CA  1 
ATOM   1820 C C   . VAL A 1 241 ? 107.052 93.264  72.103  1.00 128.80 ? 241 VAL A C   1 
ATOM   1821 O O   . VAL A 1 241 ? 106.975 94.322  72.738  1.00 128.80 ? 241 VAL A O   1 
ATOM   1822 C CB  . VAL A 1 241 ? 108.358 91.305  73.080  1.00 128.80 ? 241 VAL A CB  1 
ATOM   1823 C CG1 . VAL A 1 241 ? 107.646 91.693  74.368  1.00 128.80 ? 241 VAL A CG1 1 
ATOM   1824 C CG2 . VAL A 1 241 ? 107.753 90.057  72.461  1.00 128.80 ? 241 VAL A CG2 1 
ATOM   1825 N N   . ALA A 1 242 ? 106.040 92.763  71.405  1.00 130.55 ? 242 ALA A N   1 
ATOM   1826 C CA  . ALA A 1 242 ? 104.694 93.317  71.443  1.00 130.55 ? 242 ALA A CA  1 
ATOM   1827 C C   . ALA A 1 242 ? 103.843 92.427  72.338  1.00 130.55 ? 242 ALA A C   1 
ATOM   1828 O O   . ALA A 1 242 ? 103.784 91.210  72.129  1.00 130.55 ? 242 ALA A O   1 
ATOM   1829 C CB  . ALA A 1 242 ? 104.098 93.409  70.039  1.00 130.55 ? 242 ALA A CB  1 
ATOM   1830 N N   . ALA A 1 243 ? 103.200 93.032  73.339  1.00 133.47 ? 243 ALA A N   1 
ATOM   1831 C CA  . ALA A 1 243 ? 102.417 92.253  74.292  1.00 133.47 ? 243 ALA A CA  1 
ATOM   1832 C C   . ALA A 1 243 ? 101.250 91.550  73.611  1.00 133.47 ? 243 ALA A C   1 
ATOM   1833 O O   . ALA A 1 243 ? 100.952 90.389  73.916  1.00 133.47 ? 243 ALA A O   1 
ATOM   1834 C CB  . ALA A 1 243 ? 101.921 93.153  75.422  1.00 133.47 ? 243 ALA A CB  1 
ATOM   1835 N N   . GLY A 1 244 ? 100.587 92.224  72.689  1.00 141.99 ? 244 GLY A N   1 
ATOM   1836 C CA  . GLY A 1 244 ? 99.488  91.641  71.942  1.00 141.99 ? 244 GLY A CA  1 
ATOM   1837 C C   . GLY A 1 244 ? 98.416  92.666  71.631  1.00 141.99 ? 244 GLY A C   1 
ATOM   1838 O O   . GLY A 1 244 ? 98.357  93.750  72.212  1.00 141.99 ? 244 GLY A O   1 
ATOM   1839 N N   . LEU A 1 245 ? 97.550  92.311  70.685  1.00 150.34 ? 245 LEU A N   1 
ATOM   1840 C CA  . LEU A 1 245 ? 96.467  93.195  70.280  1.00 150.34 ? 245 LEU A CA  1 
ATOM   1841 C C   . LEU A 1 245 ? 95.439  93.332  71.397  1.00 150.34 ? 245 LEU A C   1 
ATOM   1842 O O   . LEU A 1 245 ? 95.103  92.355  72.073  1.00 150.34 ? 245 LEU A O   1 
ATOM   1843 C CB  . LEU A 1 245 ? 95.799  92.663  69.013  1.00 150.34 ? 245 LEU A CB  1 
ATOM   1844 C CG  . LEU A 1 245 ? 96.681  92.507  67.771  1.00 150.34 ? 245 LEU A CG  1 
ATOM   1845 C CD1 . LEU A 1 245 ? 95.823  92.303  66.534  1.00 150.34 ? 245 LEU A CD1 1 
ATOM   1846 C CD2 . LEU A 1 245 ? 97.597  93.710  67.594  1.00 150.34 ? 245 LEU A CD2 1 
ATOM   1847 N N   . ASN A 1 246 ? 94.925  94.554  71.565  1.00 150.43 ? 246 ASN A N   1 
ATOM   1848 C CA  . ASN A 1 246 ? 93.976  94.924  72.629  1.00 150.43 ? 246 ASN A CA  1 
ATOM   1849 C C   . ASN A 1 246 ? 94.579  94.491  73.966  1.00 150.43 ? 246 ASN A C   1 
ATOM   1850 O O   . ASN A 1 246 ? 95.727  94.854  74.257  1.00 150.43 ? 246 ASN A O   1 
ATOM   1851 C CB  . ASN A 1 246 ? 92.602  94.346  72.312  1.00 150.43 ? 246 ASN A CB  1 
ATOM   1852 C CG  . ASN A 1 246 ? 92.324  94.278  70.824  1.00 150.43 ? 246 ASN A CG  1 
ATOM   1853 O OD1 . ASN A 1 246 ? 92.267  95.303  70.144  1.00 150.43 ? 246 ASN A OD1 1 
ATOM   1854 N ND2 . ASN A 1 246 ? 92.150  93.067  70.308  1.00 150.43 ? 246 ASN A ND2 1 
ATOM   1855 N N   . ASP A 1 247 ? 93.863  93.732  74.793  1.00 149.26 ? 247 ASP A N   1 
ATOM   1856 C CA  . ASP A 1 247 ? 94.411  93.172  76.020  1.00 149.26 ? 247 ASP A CA  1 
ATOM   1857 C C   . ASP A 1 247 ? 94.625  91.668  75.919  1.00 149.26 ? 247 ASP A C   1 
ATOM   1858 O O   . ASP A 1 247 ? 94.837  91.010  76.943  1.00 149.26 ? 247 ASP A O   1 
ATOM   1859 C CB  . ASP A 1 247 ? 93.499  93.497  77.205  1.00 149.26 ? 247 ASP A CB  1 
ATOM   1860 C CG  . ASP A 1 247 ? 93.460  94.979  77.522  1.00 149.26 ? 247 ASP A CG  1 
ATOM   1861 O OD1 . ASP A 1 247 ? 94.086  95.764  76.779  1.00 149.26 ? 247 ASP A OD1 1 
ATOM   1862 O OD2 . ASP A 1 247 ? 92.806  95.360  78.515  1.00 149.26 ? 247 ASP A OD2 1 
ATOM   1863 N N   . SER A 1 248 ? 94.575  91.111  74.714  1.00 151.45 ? 248 SER A N   1 
ATOM   1864 C CA  . SER A 1 248 ? 94.731  89.681  74.504  1.00 151.45 ? 248 SER A CA  1 
ATOM   1865 C C   . SER A 1 248 ? 96.183  89.335  74.192  1.00 151.45 ? 248 SER A C   1 
ATOM   1866 O O   . SER A 1 248 ? 96.978  90.182  73.777  1.00 151.45 ? 248 SER A O   1 
ATOM   1867 C CB  . SER A 1 248 ? 93.826  89.202  73.369  1.00 151.45 ? 248 SER A CB  1 
ATOM   1868 O OG  . SER A 1 248 ? 94.307  89.649  72.113  1.00 151.45 ? 248 SER A OG  1 
ATOM   1869 N N   . ALA A 1 249 ? 96.521  88.063  74.399  1.00 149.92 ? 249 ALA A N   1 
ATOM   1870 C CA  . ALA A 1 249 ? 97.853  87.529  74.112  1.00 149.92 ? 249 ALA A CA  1 
ATOM   1871 C C   . ALA A 1 249 ? 97.670  86.278  73.257  1.00 149.92 ? 249 ALA A C   1 
ATOM   1872 O O   . ALA A 1 249 ? 97.569  85.165  73.781  1.00 149.92 ? 249 ALA A O   1 
ATOM   1873 C CB  . ALA A 1 249 ? 98.619  87.231  75.396  1.00 149.92 ? 249 ALA A CB  1 
ATOM   1874 N N   . ASP A 1 250 ? 97.627  86.466  71.941  1.00 157.13 ? 250 ASP A N   1 
ATOM   1875 C CA  . ASP A 1 250 ? 97.464  85.375  70.993  1.00 157.13 ? 250 ASP A CA  1 
ATOM   1876 C C   . ASP A 1 250 ? 98.612  85.408  69.994  1.00 157.13 ? 250 ASP A C   1 
ATOM   1877 O O   . ASP A 1 250 ? 99.012  86.480  69.528  1.00 157.13 ? 250 ASP A O   1 
ATOM   1878 C CB  . ASP A 1 250 ? 96.113  85.470  70.271  1.00 157.13 ? 250 ASP A CB  1 
ATOM   1879 C CG  . ASP A 1 250 ? 96.051  84.610  69.025  1.00 157.13 ? 250 ASP A CG  1 
ATOM   1880 O OD1 . ASP A 1 250 ? 96.512  83.449  69.069  1.00 157.13 ? 250 ASP A OD1 1 
ATOM   1881 O OD2 . ASP A 1 250 ? 95.526  85.092  68.000  1.00 157.13 ? 250 ASP A OD2 1 
ATOM   1882 N N   . MET A 1 251 ? 99.144  84.225  69.675  1.00 157.47 ? 251 MET A N   1 
ATOM   1883 C CA  . MET A 1 251 ? 100.336 84.146  68.837  1.00 157.47 ? 251 MET A CA  1 
ATOM   1884 C C   . MET A 1 251 ? 100.043 84.534  67.393  1.00 157.47 ? 251 MET A C   1 
ATOM   1885 O O   . MET A 1 251 ? 100.867 85.187  66.743  1.00 157.47 ? 251 MET A O   1 
ATOM   1886 C CB  . MET A 1 251 ? 100.927 82.739  68.901  1.00 157.47 ? 251 MET A CB  1 
ATOM   1887 C CG  . MET A 1 251 ? 101.870 82.528  70.065  1.00 157.47 ? 251 MET A CG  1 
ATOM   1888 S SD  . MET A 1 251 ? 102.706 84.054  70.529  1.00 157.47 ? 251 MET A SD  1 
ATOM   1889 C CE  . MET A 1 251 ? 103.694 83.471  71.897  1.00 157.47 ? 251 MET A CE  1 
ATOM   1890 N N   . ALA A 1 252 ? 98.882  84.146  66.873  1.00 162.64 ? 252 ALA A N   1 
ATOM   1891 C CA  . ALA A 1 252 ? 98.544  84.352  65.466  1.00 162.64 ? 252 ALA A CA  1 
ATOM   1892 C C   . ALA A 1 252 ? 97.284  85.210  65.384  1.00 162.64 ? 252 ALA A C   1 
ATOM   1893 O O   . ALA A 1 252 ? 96.171  84.692  65.269  1.00 162.64 ? 252 ALA A O   1 
ATOM   1894 C CB  . ALA A 1 252 ? 98.359  83.016  64.749  1.00 162.64 ? 252 ALA A CB  1 
ATOM   1895 N N   . SER A 1 253 ? 97.471  86.528  65.430  1.00 165.85 ? 253 SER A N   1 
ATOM   1896 C CA  . SER A 1 253 ? 96.381  87.489  65.259  1.00 165.85 ? 253 SER A CA  1 
ATOM   1897 C C   . SER A 1 253 ? 96.927  88.624  64.400  1.00 165.85 ? 253 SER A C   1 
ATOM   1898 O O   . SER A 1 253 ? 97.577  89.539  64.913  1.00 165.85 ? 253 SER A O   1 
ATOM   1899 C CB  . SER A 1 253 ? 95.864  88.001  66.598  1.00 165.85 ? 253 SER A CB  1 
ATOM   1900 O OG  . SER A 1 253 ? 96.922  88.493  67.402  1.00 165.85 ? 253 SER A OG  1 
ATOM   1901 N N   . VAL A 1 254 ? 96.670  88.550  63.091  1.00 169.70 ? 254 VAL A N   1 
ATOM   1902 C CA  . VAL A 1 254 ? 97.201  89.551  62.175  1.00 169.70 ? 254 VAL A CA  1 
ATOM   1903 C C   . VAL A 1 254 ? 96.571  90.914  62.455  1.00 169.70 ? 254 VAL A C   1 
ATOM   1904 O O   . VAL A 1 254 ? 95.504  91.031  63.071  1.00 169.70 ? 254 VAL A O   1 
ATOM   1905 C CB  . VAL A 1 254 ? 96.978  89.135  60.713  1.00 169.70 ? 254 VAL A CB  1 
ATOM   1906 C CG1 . VAL A 1 254 ? 97.843  87.934  60.369  1.00 169.70 ? 254 VAL A CG1 1 
ATOM   1907 C CG2 . VAL A 1 254 ? 95.509  88.828  60.467  1.00 169.70 ? 254 VAL A CG2 1 
ATOM   1908 N N   . ILE A 1 255 ? 97.260  91.960  62.000  1.00 172.94 ? 255 ILE A N   1 
ATOM   1909 C CA  . ILE A 1 255 ? 96.797  93.326  62.204  1.00 172.94 ? 255 ILE A CA  1 
ATOM   1910 C C   . ILE A 1 255 ? 95.503  93.541  61.434  1.00 172.94 ? 255 ILE A C   1 
ATOM   1911 O O   . ILE A 1 255 ? 95.412  93.221  60.242  1.00 172.94 ? 255 ILE A O   1 
ATOM   1912 C CB  . ILE A 1 255 ? 97.878  94.322  61.760  1.00 172.94 ? 255 ILE A CB  1 
ATOM   1913 C CG1 . ILE A 1 255 ? 99.233  93.933  62.360  1.00 172.94 ? 255 ILE A CG1 1 
ATOM   1914 C CG2 . ILE A 1 255 ? 97.486  95.734  62.153  1.00 172.94 ? 255 ILE A CG2 1 
ATOM   1915 C CD1 . ILE A 1 255 ? 100.329 94.941  62.113  1.00 172.94 ? 255 ILE A CD1 1 
ATOM   1916 N N   . ASN A 1 256 ? 94.483  94.064  62.116  1.00 174.11 ? 256 ASN A N   1 
ATOM   1917 C CA  . ASN A 1 256 ? 93.220  94.327  61.438  1.00 174.11 ? 256 ASN A CA  1 
ATOM   1918 C C   . ASN A 1 256 ? 93.128  95.774  60.966  1.00 174.11 ? 256 ASN A C   1 
ATOM   1919 O O   . ASN A 1 256 ? 93.121  96.032  59.757  1.00 174.11 ? 256 ASN A O   1 
ATOM   1920 C CB  . ASN A 1 256 ? 92.046  93.991  62.362  1.00 174.11 ? 256 ASN A CB  1 
ATOM   1921 C CG  . ASN A 1 256 ? 92.298  94.407  63.800  1.00 174.11 ? 256 ASN A CG  1 
ATOM   1922 O OD1 . ASN A 1 256 ? 93.393  94.850  64.147  1.00 174.11 ? 256 ASN A OD1 1 
ATOM   1923 N ND2 . ASN A 1 256 ? 91.282  94.269  64.644  1.00 174.11 ? 256 ASN A ND2 1 
ATOM   1924 N N   . ALA A 1 257 ? 93.093  96.718  61.910  1.00 170.74 ? 257 ALA A N   1 
ATOM   1925 C CA  . ALA A 1 257 ? 93.087  98.147  61.612  1.00 170.74 ? 257 ALA A CA  1 
ATOM   1926 C C   . ALA A 1 257 ? 93.280  98.963  62.883  1.00 170.74 ? 257 ALA A C   1 
ATOM   1927 O O   . ALA A 1 257 ? 92.525  98.796  63.847  1.00 170.74 ? 257 ALA A O   1 
ATOM   1928 C CB  . ALA A 1 257 ? 91.779  98.564  60.931  1.00 170.74 ? 257 ALA A CB  1 
ATOM   1929 N N   . GLY A 1 258 ? 94.268  99.857  62.885  1.00 162.37 ? 258 GLY A N   1 
ATOM   1930 C CA  . GLY A 1 258 ? 94.438  100.810 63.971  1.00 162.37 ? 258 GLY A CA  1 
ATOM   1931 C C   . GLY A 1 258 ? 94.597  100.204 65.348  1.00 162.37 ? 258 GLY A C   1 
ATOM   1932 O O   . GLY A 1 258 ? 94.283  100.862 66.345  1.00 162.37 ? 258 GLY A O   1 
ATOM   1933 N N   . ASP A 1 259 ? 95.077  98.968  65.435  1.00 155.90 ? 259 ASP A N   1 
ATOM   1934 C CA  . ASP A 1 259 ? 95.189  98.296  66.719  1.00 155.90 ? 259 ASP A CA  1 
ATOM   1935 C C   . ASP A 1 259 ? 96.549  98.577  67.353  1.00 155.90 ? 259 ASP A C   1 
ATOM   1936 O O   . ASP A 1 259 ? 97.491  99.023  66.697  1.00 155.90 ? 259 ASP A O   1 
ATOM   1937 C CB  . ASP A 1 259 ? 94.960  96.795  66.557  1.00 155.90 ? 259 ASP A CB  1 
ATOM   1938 C CG  . ASP A 1 259 ? 94.342  96.170  67.788  1.00 155.90 ? 259 ASP A CG  1 
ATOM   1939 O OD1 . ASP A 1 259 ? 94.178  96.889  68.795  1.00 155.90 ? 259 ASP A OD1 1 
ATOM   1940 O OD2 . ASP A 1 259 ? 94.001  94.971  67.742  1.00 155.90 ? 259 ASP A OD2 1 
ATOM   1941 N N   . VAL A 1 260 ? 96.648  98.296  68.650  1.00 147.53 ? 260 VAL A N   1 
ATOM   1942 C CA  . VAL A 1 260 ? 97.820  98.652  69.443  1.00 147.53 ? 260 VAL A CA  1 
ATOM   1943 C C   . VAL A 1 260 ? 98.808  97.492  69.448  1.00 147.53 ? 260 VAL A C   1 
ATOM   1944 O O   . VAL A 1 260 ? 98.416  96.317  69.441  1.00 147.53 ? 260 VAL A O   1 
ATOM   1945 C CB  . VAL A 1 260 ? 97.420  99.070  70.875  1.00 147.53 ? 260 VAL A CB  1 
ATOM   1946 C CG1 . VAL A 1 260 ? 96.232  100.021 70.833  1.00 147.53 ? 260 VAL A CG1 1 
ATOM   1947 C CG2 . VAL A 1 260 ? 97.094  97.864  71.746  1.00 147.53 ? 260 VAL A CG2 1 
ATOM   1948 N N   . LEU A 1 261 ? 100.098 97.824  69.394  1.00 137.08 ? 261 LEU A N   1 
ATOM   1949 C CA  . LEU A 1 261 ? 101.151 96.825  69.522  1.00 137.08 ? 261 LEU A CA  1 
ATOM   1950 C C   . LEU A 1 261 ? 101.637 96.665  70.954  1.00 137.08 ? 261 LEU A C   1 
ATOM   1951 O O   . LEU A 1 261 ? 102.042 95.562  71.338  1.00 137.08 ? 261 LEU A O   1 
ATOM   1952 C CB  . LEU A 1 261 ? 102.347 97.172  68.626  1.00 137.08 ? 261 LEU A CB  1 
ATOM   1953 C CG  . LEU A 1 261 ? 102.349 96.841  67.127  1.00 137.08 ? 261 LEU A CG  1 
ATOM   1954 C CD1 . LEU A 1 261 ? 102.552 95.346  66.915  1.00 137.08 ? 261 LEU A CD1 1 
ATOM   1955 C CD2 . LEU A 1 261 ? 101.104 97.323  66.402  1.00 137.08 ? 261 LEU A CD2 1 
ATOM   1956 N N   . ALA A 1 262 ? 101.597 97.741  71.747  1.00 126.81 ? 262 ALA A N   1 
ATOM   1957 C CA  . ALA A 1 262 ? 102.105 97.750  73.121  1.00 126.81 ? 262 ALA A CA  1 
ATOM   1958 C C   . ALA A 1 262 ? 103.564 97.297  73.171  1.00 126.81 ? 262 ALA A C   1 
ATOM   1959 O O   . ALA A 1 262 ? 103.919 96.327  73.844  1.00 126.81 ? 262 ALA A O   1 
ATOM   1960 C CB  . ALA A 1 262 ? 101.230 96.902  74.045  1.00 126.81 ? 262 ALA A CB  1 
ATOM   1961 N N   . ILE A 1 263 ? 104.411 98.015  72.436  1.00 119.72 ? 263 ILE A N   1 
ATOM   1962 C CA  . ILE A 1 263 ? 105.824 97.673  72.337  1.00 119.72 ? 263 ILE A CA  1 
ATOM   1963 C C   . ILE A 1 263 ? 106.497 97.879  73.689  1.00 119.72 ? 263 ILE A C   1 
ATOM   1964 O O   . ILE A 1 263 ? 106.273 98.891  74.366  1.00 119.72 ? 263 ILE A O   1 
ATOM   1965 C CB  . ILE A 1 263 ? 106.490 98.511  71.235  1.00 119.72 ? 263 ILE A CB  1 
ATOM   1966 C CG1 . ILE A 1 263 ? 106.321 97.829  69.881  1.00 119.72 ? 263 ILE A CG1 1 
ATOM   1967 C CG2 . ILE A 1 263 ? 107.963 98.727  71.518  1.00 119.72 ? 263 ILE A CG2 1 
ATOM   1968 C CD1 . ILE A 1 263 ? 107.145 96.583  69.744  1.00 119.72 ? 263 ILE A CD1 1 
ATOM   1969 N N   . SER A 1 264 ? 107.315 96.909  74.097  1.00 114.70 ? 264 SER A N   1 
ATOM   1970 C CA  . SER A 1 264 ? 108.055 96.986  75.347  1.00 114.70 ? 264 SER A CA  1 
ATOM   1971 C C   . SER A 1 264 ? 109.547 96.860  75.070  1.00 114.70 ? 264 SER A C   1 
ATOM   1972 O O   . SER A 1 264 ? 109.971 96.011  74.280  1.00 114.70 ? 264 SER A O   1 
ATOM   1973 C CB  . SER A 1 264 ? 107.609 95.891  76.317  1.00 114.70 ? 264 SER A CB  1 
ATOM   1974 O OG  . SER A 1 264 ? 107.815 94.608  75.756  1.00 114.70 ? 264 SER A OG  1 
ATOM   1975 N N   . GLY A 1 265 ? 110.336 97.709  75.718  1.00 114.67 ? 265 GLY A N   1 
ATOM   1976 C CA  . GLY A 1 265 ? 111.777 97.670  75.555  1.00 114.67 ? 265 GLY A CA  1 
ATOM   1977 C C   . GLY A 1 265 ? 112.396 99.010  75.919  1.00 114.67 ? 265 GLY A C   1 
ATOM   1978 O O   . GLY A 1 265 ? 111.751 99.862  76.526  1.00 114.67 ? 265 GLY A O   1 
ATOM   1979 N N   . GLY A 1 266 ? 113.662 99.162  75.534  1.00 121.64 ? 266 GLY A N   1 
ATOM   1980 C CA  . GLY A 1 266 ? 114.369 100.403 75.792  1.00 121.64 ? 266 GLY A CA  1 
ATOM   1981 C C   . GLY A 1 266 ? 113.915 101.518 74.870  1.00 121.64 ? 266 GLY A C   1 
ATOM   1982 O O   . GLY A 1 266 ? 113.451 101.284 73.757  1.00 121.64 ? 266 GLY A O   1 
ATOM   1983 N N   . ILE A 1 267 ? 114.066 102.757 75.349  1.00 120.21 ? 267 ILE A N   1 
ATOM   1984 C CA  . ILE A 1 267 ? 113.499 103.914 74.654  1.00 120.21 ? 267 ILE A CA  1 
ATOM   1985 C C   . ILE A 1 267 ? 114.128 104.084 73.274  1.00 120.21 ? 267 ILE A C   1 
ATOM   1986 O O   . ILE A 1 267 ? 113.428 104.273 72.271  1.00 120.21 ? 267 ILE A O   1 
ATOM   1987 C CB  . ILE A 1 267 ? 113.662 105.182 75.515  1.00 120.21 ? 267 ILE A CB  1 
ATOM   1988 C CG1 . ILE A 1 267 ? 112.554 105.260 76.566  1.00 120.21 ? 267 ILE A CG1 1 
ATOM   1989 C CG2 . ILE A 1 267 ? 113.658 106.432 74.655  1.00 120.21 ? 267 ILE A CG2 1 
ATOM   1990 C CD1 . ILE A 1 267 ? 112.657 106.467 77.477  1.00 120.21 ? 267 ILE A CD1 1 
ATOM   1991 N N   . ASP A 1 268 ? 115.458 104.008 73.200  1.00 127.12 ? 268 ASP A N   1 
ATOM   1992 C CA  . ASP A 1 268 ? 116.142 104.160 71.918  1.00 127.12 ? 268 ASP A CA  1 
ATOM   1993 C C   . ASP A 1 268 ? 115.790 103.018 70.972  1.00 127.12 ? 268 ASP A C   1 
ATOM   1994 O O   . ASP A 1 268 ? 115.668 103.211 69.753  1.00 127.12 ? 268 ASP A O   1 
ATOM   1995 C CB  . ASP A 1 268 ? 117.652 104.233 72.150  1.00 127.12 ? 268 ASP A CB  1 
ATOM   1996 C CG  . ASP A 1 268 ? 118.382 104.965 71.042  1.00 127.12 ? 268 ASP A CG  1 
ATOM   1997 O OD1 . ASP A 1 268 ? 118.192 104.608 69.863  1.00 127.12 ? 268 ASP A OD1 1 
ATOM   1998 O OD2 . ASP A 1 268 ? 119.149 105.903 71.350  1.00 127.12 ? 268 ASP A OD2 1 
ATOM   1999 N N   . GLU A 1 269 ? 115.631 101.815 71.521  1.00 127.86 ? 269 GLU A N   1 
ATOM   2000 C CA  . GLU A 1 269 ? 115.256 100.660 70.715  1.00 127.86 ? 269 GLU A CA  1 
ATOM   2001 C C   . GLU A 1 269 ? 113.858 100.831 70.128  1.00 127.86 ? 269 GLU A C   1 
ATOM   2002 O O   . GLU A 1 269 ? 113.632 100.545 68.944  1.00 127.86 ? 269 GLU A O   1 
ATOM   2003 C CB  . GLU A 1 269 ? 115.357 99.403  71.578  1.00 127.86 ? 269 GLU A CB  1 
ATOM   2004 C CG  . GLU A 1 269 ? 116.788 99.040  71.956  1.00 127.86 ? 269 GLU A CG  1 
ATOM   2005 C CD  . GLU A 1 269 ? 116.897 97.717  72.692  1.00 127.86 ? 269 GLU A CD  1 
ATOM   2006 O OE1 . GLU A 1 269 ? 115.953 96.907  72.628  1.00 127.86 ? 269 GLU A OE1 1 
ATOM   2007 O OE2 . GLU A 1 269 ? 117.941 97.486  73.339  1.00 127.86 ? 269 GLU A OE2 1 
ATOM   2008 N N   . ILE A 1 270 ? 112.917 101.335 70.932  1.00 124.66 ? 270 ILE A N   1 
ATOM   2009 C CA  . ILE A 1 270 ? 111.580 101.637 70.427  1.00 124.66 ? 270 ILE A CA  1 
ATOM   2010 C C   . ILE A 1 270 ? 111.646 102.733 69.372  1.00 124.66 ? 270 ILE A C   1 
ATOM   2011 O O   . ILE A 1 270 ? 110.888 102.720 68.398  1.00 124.66 ? 270 ILE A O   1 
ATOM   2012 C CB  . ILE A 1 270 ? 110.628 102.018 71.579  1.00 124.66 ? 270 ILE A CB  1 
ATOM   2013 C CG1 . ILE A 1 270 ? 110.584 100.923 72.646  1.00 124.66 ? 270 ILE A CG1 1 
ATOM   2014 C CG2 . ILE A 1 270 ? 109.224 102.290 71.058  1.00 124.66 ? 270 ILE A CG2 1 
ATOM   2015 C CD1 . ILE A 1 270 ? 110.189 101.424 74.019  1.00 124.66 ? 270 ILE A CD1 1 
ATOM   2016 N N   . GLY A 1 271 ? 112.548 103.699 69.552  1.00 129.46 ? 271 GLY A N   1 
ATOM   2017 C CA  . GLY A 1 271 ? 112.695 104.749 68.556  1.00 129.46 ? 271 GLY A CA  1 
ATOM   2018 C C   . GLY A 1 271 ? 113.150 104.225 67.207  1.00 129.46 ? 271 GLY A C   1 
ATOM   2019 O O   . GLY A 1 271 ? 112.593 104.591 66.165  1.00 129.46 ? 271 GLY A O   1 
ATOM   2020 N N   . ARG A 1 272 ? 114.167 103.355 67.203  1.00 132.12 ? 272 ARG A N   1 
ATOM   2021 C CA  . ARG A 1 272 ? 114.581 102.755 65.936  1.00 132.12 ? 272 ARG A CA  1 
ATOM   2022 C C   . ARG A 1 272 ? 113.487 101.862 65.364  1.00 132.12 ? 272 ARG A C   1 
ATOM   2023 O O   . ARG A 1 272 ? 113.337 101.764 64.142  1.00 132.12 ? 272 ARG A O   1 
ATOM   2024 C CB  . ARG A 1 272 ? 115.891 101.975 66.062  1.00 132.12 ? 272 ARG A CB  1 
ATOM   2025 C CG  . ARG A 1 272 ? 117.126 102.849 65.888  1.00 132.12 ? 272 ARG A CG  1 
ATOM   2026 C CD  . ARG A 1 272 ? 118.431 102.127 66.204  1.00 132.12 ? 272 ARG A CD  1 
ATOM   2027 N NE  . ARG A 1 272 ? 118.311 101.066 67.197  1.00 132.12 ? 272 ARG A NE  1 
ATOM   2028 C CZ  . ARG A 1 272 ? 118.260 101.268 68.505  1.00 132.12 ? 272 ARG A CZ  1 
ATOM   2029 N NH1 . ARG A 1 272 ? 118.292 102.483 69.018  1.00 132.12 ? 272 ARG A NH1 1 
ATOM   2030 N NH2 . ARG A 1 272 ? 118.190 100.223 69.318  1.00 132.12 ? 272 ARG A NH2 1 
ATOM   2031 N N   . ALA A 1 273 ? 112.702 101.213 66.228  1.00 135.70 ? 273 ALA A N   1 
ATOM   2032 C CA  . ALA A 1 273 ? 111.570 100.429 65.735  1.00 135.70 ? 273 ALA A CA  1 
ATOM   2033 C C   . ALA A 1 273 ? 110.543 101.311 65.032  1.00 135.70 ? 273 ALA A C   1 
ATOM   2034 O O   . ALA A 1 273 ? 110.028 100.954 63.964  1.00 135.70 ? 273 ALA A O   1 
ATOM   2035 C CB  . ALA A 1 273 ? 110.916 99.669  66.887  1.00 135.70 ? 273 ALA A CB  1 
ATOM   2036 N N   . VAL A 1 274 ? 110.229 102.464 65.626  1.00 139.49 ? 274 VAL A N   1 
ATOM   2037 C CA  . VAL A 1 274 ? 109.258 103.384 65.037  1.00 139.49 ? 274 VAL A CA  1 
ATOM   2038 C C   . VAL A 1 274 ? 109.774 103.927 63.712  1.00 139.49 ? 274 VAL A C   1 
ATOM   2039 O O   . VAL A 1 274 ? 109.010 104.090 62.752  1.00 139.49 ? 274 VAL A O   1 
ATOM   2040 C CB  . VAL A 1 274 ? 108.917 104.516 66.025  1.00 139.49 ? 274 VAL A CB  1 
ATOM   2041 C CG1 . VAL A 1 274 ? 108.003 105.545 65.372  1.00 139.49 ? 274 VAL A CG1 1 
ATOM   2042 C CG2 . VAL A 1 274 ? 108.234 103.946 67.250  1.00 139.49 ? 274 VAL A CG2 1 
ATOM   2043 N N   . GLN A 1 275 ? 111.073 104.219 63.631  1.00 141.79 ? 275 GLN A N   1 
ATOM   2044 C CA  . GLN A 1 275 ? 111.610 104.656 62.345  1.00 141.79 ? 275 GLN A CA  1 
ATOM   2045 C C   . GLN A 1 275 ? 111.629 103.531 61.318  1.00 141.79 ? 275 GLN A C   1 
ATOM   2046 O O   . GLN A 1 275 ? 111.485 103.792 60.118  1.00 141.79 ? 275 GLN A O   1 
ATOM   2047 C CB  . GLN A 1 275 ? 113.001 105.256 62.512  1.00 141.79 ? 275 GLN A CB  1 
ATOM   2048 C CG  . GLN A 1 275 ? 112.975 106.546 63.282  1.00 141.79 ? 275 GLN A CG  1 
ATOM   2049 C CD  . GLN A 1 275 ? 113.882 107.584 62.670  1.00 141.79 ? 275 GLN A CD  1 
ATOM   2050 O OE1 . GLN A 1 275 ? 114.568 107.325 61.682  1.00 141.79 ? 275 GLN A OE1 1 
ATOM   2051 N NE2 . GLN A 1 275 ? 113.853 108.783 63.223  1.00 141.79 ? 275 GLN A NE2 1 
ATOM   2052 N N   . GLU A 1 276 ? 111.814 102.284 61.756  1.00 150.81 ? 276 GLU A N   1 
ATOM   2053 C CA  . GLU A 1 276 ? 111.709 101.163 60.829  1.00 150.81 ? 276 GLU A CA  1 
ATOM   2054 C C   . GLU A 1 276 ? 110.291 101.032 60.286  1.00 150.81 ? 276 GLU A C   1 
ATOM   2055 O O   . GLU A 1 276 ? 110.095 100.796 59.088  1.00 150.81 ? 276 GLU A O   1 
ATOM   2056 C CB  . GLU A 1 276 ? 112.146 99.868  61.514  1.00 150.81 ? 276 GLU A CB  1 
ATOM   2057 C CG  . GLU A 1 276 ? 111.855 98.613  60.706  1.00 150.81 ? 276 GLU A CG  1 
ATOM   2058 C CD  . GLU A 1 276 ? 111.737 97.372  61.568  1.00 150.81 ? 276 GLU A CD  1 
ATOM   2059 O OE1 . GLU A 1 276 ? 111.743 97.503  62.810  1.00 150.81 ? 276 GLU A OE1 1 
ATOM   2060 O OE2 . GLU A 1 276 ? 111.635 96.263  61.002  1.00 150.81 ? 276 GLU A OE2 1 
ATOM   2061 N N   . PHE A 1 277 ? 109.288 101.191 61.149  1.00 154.82 ? 277 PHE A N   1 
ATOM   2062 C CA  . PHE A 1 277 ? 107.891 101.113 60.733  1.00 154.82 ? 277 PHE A CA  1 
ATOM   2063 C C   . PHE A 1 277 ? 107.087 102.094 61.572  1.00 154.82 ? 277 PHE A C   1 
ATOM   2064 O O   . PHE A 1 277 ? 107.091 102.008 62.804  1.00 154.82 ? 277 PHE A O   1 
ATOM   2065 C CB  . PHE A 1 277 ? 107.354 99.684  60.880  1.00 154.82 ? 277 PHE A CB  1 
ATOM   2066 C CG  . PHE A 1 277 ? 105.864 99.603  61.047  1.00 154.82 ? 277 PHE A CG  1 
ATOM   2067 C CD1 . PHE A 1 277 ? 105.015 100.071 60.055  1.00 154.82 ? 277 PHE A CD1 1 
ATOM   2068 C CD2 . PHE A 1 277 ? 105.312 99.041  62.184  1.00 154.82 ? 277 PHE A CD2 1 
ATOM   2069 C CE1 . PHE A 1 277 ? 103.647 99.992  60.203  1.00 154.82 ? 277 PHE A CE1 1 
ATOM   2070 C CE2 . PHE A 1 277 ? 103.944 98.957  62.335  1.00 154.82 ? 277 PHE A CE2 1 
ATOM   2071 C CZ  . PHE A 1 277 ? 103.111 99.434  61.344  1.00 154.82 ? 277 PHE A CZ  1 
ATOM   2072 N N   . ASN A 1 278 ? 106.396 103.017 60.903  1.00 155.46 ? 278 ASN A N   1 
ATOM   2073 C CA  . ASN A 1 278 ? 105.727 104.119 61.585  1.00 155.46 ? 278 ASN A CA  1 
ATOM   2074 C C   . ASN A 1 278 ? 104.560 103.622 62.433  1.00 155.46 ? 278 ASN A C   1 
ATOM   2075 O O   . ASN A 1 278 ? 103.856 102.679 62.063  1.00 155.46 ? 278 ASN A O   1 
ATOM   2076 C CB  . ASN A 1 278 ? 105.232 105.143 60.562  1.00 155.46 ? 278 ASN A CB  1 
ATOM   2077 C CG  . ASN A 1 278 ? 104.749 106.431 61.205  1.00 155.46 ? 278 ASN A CG  1 
ATOM   2078 O OD1 . ASN A 1 278 ? 104.905 106.639 62.409  1.00 155.46 ? 278 ASN A OD1 1 
ATOM   2079 N ND2 . ASN A 1 278 ? 104.154 107.304 60.400  1.00 155.46 ? 278 ASN A ND2 1 
ATOM   2080 N N   . LEU A 1 279 ? 104.356 104.279 63.575  1.00 147.75 ? 279 LEU A N   1 
ATOM   2081 C CA  . LEU A 1 279 ? 103.306 103.916 64.516  1.00 147.75 ? 279 LEU A CA  1 
ATOM   2082 C C   . LEU A 1 279 ? 102.829 105.174 65.229  1.00 147.75 ? 279 LEU A C   1 
ATOM   2083 O O   . LEU A 1 279 ? 103.573 106.147 65.371  1.00 147.75 ? 279 LEU A O   1 
ATOM   2084 C CB  . LEU A 1 279 ? 103.804 102.876 65.526  1.00 147.75 ? 279 LEU A CB  1 
ATOM   2085 C CG  . LEU A 1 279 ? 103.796 101.414 65.078  1.00 147.75 ? 279 LEU A CG  1 
ATOM   2086 C CD1 . LEU A 1 279 ? 104.469 100.521 66.106  1.00 147.75 ? 279 LEU A CD1 1 
ATOM   2087 C CD2 . LEU A 1 279 ? 102.369 100.956 64.828  1.00 147.75 ? 279 LEU A CD2 1 
ATOM   2088 N N   . LEU A 1 280 ? 101.573 105.149 65.676  1.00 144.83 ? 280 LEU A N   1 
ATOM   2089 C CA  . LEU A 1 280 ? 100.969 106.281 66.372  1.00 144.83 ? 280 LEU A CA  1 
ATOM   2090 C C   . LEU A 1 280 ? 101.134 106.078 67.872  1.00 144.83 ? 280 LEU A C   1 
ATOM   2091 O O   . LEU A 1 280 ? 100.607 105.110 68.426  1.00 144.83 ? 280 LEU A O   1 
ATOM   2092 C CB  . LEU A 1 280 ? 99.480  106.423 66.045  1.00 144.83 ? 280 LEU A CB  1 
ATOM   2093 C CG  . LEU A 1 280 ? 98.865  106.875 64.712  1.00 144.83 ? 280 LEU A CG  1 
ATOM   2094 C CD1 . LEU A 1 280 ? 99.137  108.354 64.441  1.00 144.83 ? 280 LEU A CD1 1 
ATOM   2095 C CD2 . LEU A 1 280 ? 99.248  105.990 63.527  1.00 144.83 ? 280 LEU A CD2 1 
ATOM   2096 N N   . GLU A 1 281 ? 101.837 106.991 68.534  1.00 137.98 ? 281 GLU A N   1 
ATOM   2097 C CA  . GLU A 1 281 ? 101.994 106.890 69.982  1.00 137.98 ? 281 GLU A CA  1 
ATOM   2098 C C   . GLU A 1 281 ? 100.745 107.456 70.647  1.00 137.98 ? 281 GLU A C   1 
ATOM   2099 O O   . GLU A 1 281 ? 100.492 108.663 70.589  1.00 137.98 ? 281 GLU A O   1 
ATOM   2100 C CB  . GLU A 1 281 ? 103.250 107.615 70.451  1.00 137.98 ? 281 GLU A CB  1 
ATOM   2101 C CG  . GLU A 1 281 ? 103.483 107.497 71.950  1.00 137.98 ? 281 GLU A CG  1 
ATOM   2102 C CD  . GLU A 1 281 ? 104.946 107.595 72.331  1.00 137.98 ? 281 GLU A CD  1 
ATOM   2103 O OE1 . GLU A 1 281 ? 105.667 108.415 71.727  1.00 137.98 ? 281 GLU A OE1 1 
ATOM   2104 O OE2 . GLU A 1 281 ? 105.376 106.846 73.234  1.00 137.98 ? 281 GLU A OE2 1 
ATOM   2105 N N   . VAL A 1 282 ? 99.963  106.582 71.276  1.00 134.84 ? 282 VAL A N   1 
ATOM   2106 C CA  . VAL A 1 282 ? 98.700  106.942 71.907  1.00 134.84 ? 282 VAL A CA  1 
ATOM   2107 C C   . VAL A 1 282 ? 98.768  106.544 73.374  1.00 134.84 ? 282 VAL A C   1 
ATOM   2108 O O   . VAL A 1 282 ? 99.332  105.498 73.714  1.00 134.84 ? 282 VAL A O   1 
ATOM   2109 C CB  . VAL A 1 282 ? 97.503  106.262 71.207  1.00 134.84 ? 282 VAL A CB  1 
ATOM   2110 C CG1 . VAL A 1 282 ? 96.185  106.771 71.772  1.00 134.84 ? 282 VAL A CG1 1 
ATOM   2111 C CG2 . VAL A 1 282 ? 97.563  106.490 69.703  1.00 134.84 ? 282 VAL A CG2 1 
ATOM   2112 N N   . THR A 1 283 ? 98.206  107.391 74.244  1.00 131.35 ? 283 THR A N   1 
ATOM   2113 C CA  . THR A 1 283 ? 98.274  107.135 75.680  1.00 131.35 ? 283 THR A CA  1 
ATOM   2114 C C   . THR A 1 283 ? 97.560  105.839 76.062  1.00 131.35 ? 283 THR A C   1 
ATOM   2115 O O   . THR A 1 283 ? 98.071  105.064 76.878  1.00 131.35 ? 283 THR A O   1 
ATOM   2116 C CB  . THR A 1 283 ? 97.718  108.335 76.458  1.00 131.35 ? 283 THR A CB  1 
ATOM   2117 O OG1 . THR A 1 283 ? 97.805  108.085 77.867  1.00 131.35 ? 283 THR A OG1 1 
ATOM   2118 C CG2 . THR A 1 283 ? 96.277  108.668 76.065  1.00 131.35 ? 283 THR A CG2 1 
ATOM   2119 N N   . GLY A 1 284 ? 96.389  105.580 75.482  1.00 138.68 ? 284 GLY A N   1 
ATOM   2120 C CA  . GLY A 1 284 ? 95.667  104.350 75.752  1.00 138.68 ? 284 GLY A CA  1 
ATOM   2121 C C   . GLY A 1 284 ? 95.072  104.256 77.143  1.00 138.68 ? 284 GLY A C   1 
ATOM   2122 O O   . GLY A 1 284 ? 95.467  104.992 78.052  1.00 138.68 ? 284 GLY A O   1 
ATOM   2123 N N   . LYS A 1 285 ? 94.109  103.354 77.321  1.00 140.99 ? 285 LYS A N   1 
ATOM   2124 C CA  . LYS A 1 285 ? 93.497  103.095 78.624  1.00 140.99 ? 285 LYS A CA  1 
ATOM   2125 C C   . LYS A 1 285 ? 93.364  101.587 78.815  1.00 140.99 ? 285 LYS A C   1 
ATOM   2126 O O   . LYS A 1 285 ? 92.419  100.973 78.312  1.00 140.99 ? 285 LYS A O   1 
ATOM   2127 C CB  . LYS A 1 285 ? 92.143  103.787 78.749  1.00 140.99 ? 285 LYS A CB  1 
ATOM   2128 C CG  . LYS A 1 285 ? 91.526  103.668 80.134  1.00 140.99 ? 285 LYS A CG  1 
ATOM   2129 C CD  . LYS A 1 285 ? 92.475  104.159 81.215  1.00 140.99 ? 285 LYS A CD  1 
ATOM   2130 C CE  . LYS A 1 285 ? 91.715  104.625 82.446  1.00 140.99 ? 285 LYS A CE  1 
ATOM   2131 N NZ  . LYS A 1 285 ? 92.461  105.671 83.193  1.00 140.99 ? 285 LYS A NZ  1 
ATOM   2132 N N   . THR A 1 286 ? 94.309  100.999 79.548  1.00 144.99 ? 286 THR A N   1 
ATOM   2133 C CA  . THR A 1 286 ? 94.242  99.585  79.898  1.00 144.99 ? 286 THR A CA  1 
ATOM   2134 C C   . THR A 1 286 ? 95.054  99.353  81.165  1.00 144.99 ? 286 THR A C   1 
ATOM   2135 O O   . THR A 1 286 ? 96.185  99.837  81.283  1.00 144.99 ? 286 THR A O   1 
ATOM   2136 C CB  . THR A 1 286 ? 94.734  98.692  78.743  1.00 144.99 ? 286 THR A CB  1 
ATOM   2137 O OG1 . THR A 1 286 ? 94.672  97.314  79.136  1.00 144.99 ? 286 THR A OG1 1 
ATOM   2138 C CG2 . THR A 1 286 ? 96.152  99.051  78.299  1.00 144.99 ? 286 THR A CG2 1 
ATOM   2139 N N   . LYS A 1 287 ? 94.456  98.654  82.128  1.00 146.78 ? 287 LYS A N   1 
ATOM   2140 C CA  . LYS A 1 287 ? 95.111  98.341  83.391  1.00 146.78 ? 287 LYS A CA  1 
ATOM   2141 C C   . LYS A 1 287 ? 95.661  96.923  83.439  1.00 146.78 ? 287 LYS A C   1 
ATOM   2142 O O   . LYS A 1 287 ? 96.175  96.509  84.482  1.00 146.78 ? 287 LYS A O   1 
ATOM   2143 C CB  . LYS A 1 287 ? 94.143  98.559  84.560  1.00 146.78 ? 287 LYS A CB  1 
ATOM   2144 C CG  . LYS A 1 287 ? 93.022  99.555  84.282  1.00 146.78 ? 287 LYS A CG  1 
ATOM   2145 C CD  . LYS A 1 287 ? 93.528  100.994 84.234  1.00 146.78 ? 287 LYS A CD  1 
ATOM   2146 C CE  . LYS A 1 287 ? 94.469  101.305 85.389  1.00 146.78 ? 287 LYS A CE  1 
ATOM   2147 N NZ  . LYS A 1 287 ? 95.053  102.670 85.280  1.00 146.78 ? 287 LYS A NZ  1 
ATOM   2148 N N   . ALA A 1 288 ? 95.545  96.163  82.350  1.00 148.61 ? 288 ALA A N   1 
ATOM   2149 C CA  . ALA A 1 288 ? 96.058  94.797  82.343  1.00 148.61 ? 288 ALA A CA  1 
ATOM   2150 C C   . ALA A 1 288 ? 97.577  94.769  82.221  1.00 148.61 ? 288 ALA A C   1 
ATOM   2151 O O   . ALA A 1 288 ? 98.243  93.954  82.868  1.00 148.61 ? 288 ALA A O   1 
ATOM   2152 C CB  . ALA A 1 288 ? 95.414  94.002  81.208  1.00 148.61 ? 288 ALA A CB  1 
ATOM   2153 N N   . TYR A 1 289 ? 98.140  95.654  81.399  1.00 140.41 ? 289 TYR A N   1 
ATOM   2154 C CA  . TYR A 1 289 ? 99.555  95.598  81.028  1.00 140.41 ? 289 TYR A CA  1 
ATOM   2155 C C   . TYR A 1 289 ? 100.382 96.275  82.119  1.00 140.41 ? 289 TYR A C   1 
ATOM   2156 O O   . TYR A 1 289 ? 100.766 97.444  82.028  1.00 140.41 ? 289 TYR A O   1 
ATOM   2157 C CB  . TYR A 1 289 ? 99.766  96.251  79.668  1.00 140.41 ? 289 TYR A CB  1 
ATOM   2158 C CG  . TYR A 1 289 ? 99.283  95.422  78.491  1.00 140.41 ? 289 TYR A CG  1 
ATOM   2159 C CD1 . TYR A 1 289 ? 98.534  94.266  78.681  1.00 140.41 ? 289 TYR A CD1 1 
ATOM   2160 C CD2 . TYR A 1 289 ? 99.545  95.819  77.187  1.00 140.41 ? 289 TYR A CD2 1 
ATOM   2161 C CE1 . TYR A 1 289 ? 98.085  93.517  77.610  1.00 140.41 ? 289 TYR A CE1 1 
ATOM   2162 C CE2 . TYR A 1 289 ? 99.093  95.078  76.111  1.00 140.41 ? 289 TYR A CE2 1 
ATOM   2163 C CZ  . TYR A 1 289 ? 98.368  93.928  76.328  1.00 140.41 ? 289 TYR A CZ  1 
ATOM   2164 O OH  . TYR A 1 289 ? 97.922  93.189  75.256  1.00 140.41 ? 289 TYR A OH  1 
ATOM   2165 N N   . VAL A 1 290 ? 100.664 95.513  83.178  1.00 142.08 ? 290 VAL A N   1 
ATOM   2166 C CA  . VAL A 1 290 ? 101.390 96.003  84.345  1.00 142.08 ? 290 VAL A CA  1 
ATOM   2167 C C   . VAL A 1 290 ? 102.525 95.038  84.661  1.00 142.08 ? 290 VAL A C   1 
ATOM   2168 O O   . VAL A 1 290 ? 102.363 93.818  84.556  1.00 142.08 ? 290 VAL A O   1 
ATOM   2169 C CB  . VAL A 1 290 ? 100.460 96.171  85.570  1.00 142.08 ? 290 VAL A CB  1 
ATOM   2170 C CG1 . VAL A 1 290 ? 101.209 96.794  86.740  1.00 142.08 ? 290 VAL A CG1 1 
ATOM   2171 C CG2 . VAL A 1 290 ? 99.258  97.025  85.219  1.00 142.08 ? 290 VAL A CG2 1 
ATOM   2172 N N   . SER A 1 291 ? 103.674 95.590  85.047  1.00 149.69 ? 291 SER A N   1 
ATOM   2173 C CA  . SER A 1 291 ? 104.852 94.809  85.386  1.00 149.69 ? 291 SER A CA  1 
ATOM   2174 C C   . SER A 1 291 ? 104.734 94.217  86.786  1.00 149.69 ? 291 SER A C   1 
ATOM   2175 O O   . SER A 1 291 ? 103.947 94.675  87.618  1.00 149.69 ? 291 SER A O   1 
ATOM   2176 C CB  . SER A 1 291 ? 106.107 95.675  85.309  1.00 149.69 ? 291 SER A CB  1 
ATOM   2177 O OG  . SER A 1 291 ? 106.180 96.564  86.410  1.00 149.69 ? 291 SER A OG  1 
ATOM   2178 N N   . LYS A 1 292 ? 105.546 93.192  87.046  1.00 155.42 ? 292 LYS A N   1 
ATOM   2179 C CA  . LYS A 1 292 ? 105.610 92.582  88.368  1.00 155.42 ? 292 LYS A CA  1 
ATOM   2180 C C   . LYS A 1 292 ? 107.029 92.108  88.654  1.00 155.42 ? 292 LYS A C   1 
ATOM   2181 O O   . LYS A 1 292 ? 107.764 91.707  87.747  1.00 155.42 ? 292 LYS A O   1 
ATOM   2182 C CB  . LYS A 1 292 ? 104.633 91.406  88.508  1.00 155.42 ? 292 LYS A CB  1 
ATOM   2183 C CG  . LYS A 1 292 ? 103.201 91.811  88.828  1.00 155.42 ? 292 LYS A CG  1 
ATOM   2184 C CD  . LYS A 1 292 ? 103.151 92.690  90.071  1.00 155.42 ? 292 LYS A CD  1 
ATOM   2185 C CE  . LYS A 1 292 ? 101.723 92.914  90.543  1.00 155.42 ? 292 LYS A CE  1 
ATOM   2186 N NZ  . LYS A 1 292 ? 101.067 91.642  90.951  1.00 155.42 ? 292 LYS A NZ  1 
ATOM   2187 N N   . GLN A 1 293 ? 107.394 92.145  89.934  1.00 166.79 ? 293 GLN A N   1 
ATOM   2188 C CA  . GLN A 1 293 ? 108.684 91.670  90.419  1.00 166.79 ? 293 GLN A CA  1 
ATOM   2189 C C   . GLN A 1 293 ? 108.483 90.387  91.214  1.00 166.79 ? 293 GLN A C   1 
ATOM   2190 O O   . GLN A 1 293 ? 107.601 90.319  92.077  1.00 166.79 ? 293 GLN A O   1 
ATOM   2191 C CB  . GLN A 1 293 ? 109.372 92.726  91.286  1.00 166.79 ? 293 GLN A CB  1 
ATOM   2192 C CG  . GLN A 1 293 ? 108.910 94.146  91.024  1.00 166.79 ? 293 GLN A CG  1 
ATOM   2193 C CD  . GLN A 1 293 ? 109.451 95.127  92.044  1.00 166.79 ? 293 GLN A CD  1 
ATOM   2194 O OE1 . GLN A 1 293 ? 110.629 95.086  92.396  1.00 166.79 ? 293 GLN A OE1 1 
ATOM   2195 N NE2 . GLN A 1 293 ? 108.589 96.015  92.526  1.00 166.79 ? 293 GLN A NE2 1 
ATOM   2196 N N   . VAL A 1 294 ? 109.295 89.375  90.916  1.00 170.71 ? 294 VAL A N   1 
ATOM   2197 C CA  . VAL A 1 294 ? 109.144 88.032  91.465  1.00 170.71 ? 294 VAL A CA  1 
ATOM   2198 C C   . VAL A 1 294 ? 110.526 87.471  91.774  1.00 170.71 ? 294 VAL A C   1 
ATOM   2199 O O   . VAL A 1 294 ? 111.447 87.595  90.959  1.00 170.71 ? 294 VAL A O   1 
ATOM   2200 C CB  . VAL A 1 294 ? 108.383 87.118  90.482  1.00 170.71 ? 294 VAL A CB  1 
ATOM   2201 C CG1 . VAL A 1 294 ? 108.596 85.647  90.811  1.00 170.71 ? 294 VAL A CG1 1 
ATOM   2202 C CG2 . VAL A 1 294 ? 106.903 87.464  90.482  1.00 170.71 ? 294 VAL A CG2 1 
ATOM   2203 N N   . VAL A 1 295 ? 110.677 86.864  92.954  1.00 173.43 ? 295 VAL A N   1 
ATOM   2204 C CA  . VAL A 1 295 ? 111.919 86.190  93.316  1.00 173.43 ? 295 VAL A CA  1 
ATOM   2205 C C   . VAL A 1 295 ? 111.913 84.782  92.731  1.00 173.43 ? 295 VAL A C   1 
ATOM   2206 O O   . VAL A 1 295 ? 110.888 84.092  92.739  1.00 173.43 ? 295 VAL A O   1 
ATOM   2207 C CB  . VAL A 1 295 ? 112.106 86.186  94.847  1.00 173.43 ? 295 VAL A CB  1 
ATOM   2208 C CG1 . VAL A 1 295 ? 110.834 85.751  95.551  1.00 173.43 ? 295 VAL A CG1 1 
ATOM   2209 C CG2 . VAL A 1 295 ? 113.286 85.312  95.265  1.00 173.43 ? 295 VAL A CG2 1 
ATOM   2210 N N   . LEU A 1 296 ? 113.061 84.354  92.212  1.00 180.45 ? 296 LEU A N   1 
ATOM   2211 C CA  . LEU A 1 296 ? 113.162 83.103  91.476  1.00 180.45 ? 296 LEU A CA  1 
ATOM   2212 C C   . LEU A 1 296 ? 113.413 81.928  92.418  1.00 180.45 ? 296 LEU A C   1 
ATOM   2213 O O   . LEU A 1 296 ? 113.673 82.092  93.612  1.00 180.45 ? 296 LEU A O   1 
ATOM   2214 C CB  . LEU A 1 296 ? 114.278 83.186  90.433  1.00 180.45 ? 296 LEU A CB  1 
ATOM   2215 C CG  . LEU A 1 296 ? 114.041 84.082  89.215  1.00 180.45 ? 296 LEU A CG  1 
ATOM   2216 C CD1 . LEU A 1 296 ? 114.786 83.546  88.002  1.00 180.45 ? 296 LEU A CD1 1 
ATOM   2217 C CD2 . LEU A 1 296 ? 112.557 84.236  88.923  1.00 180.45 ? 296 LEU A CD2 1 
ATOM   2218 N N   . LYS A 1 297 ? 113.316 80.724  91.861  1.00 185.06 ? 297 LYS A N   1 
ATOM   2219 C CA  . LYS A 1 297 ? 113.628 79.505  92.588  1.00 185.06 ? 297 LYS A CA  1 
ATOM   2220 C C   . LYS A 1 297 ? 115.109 79.161  92.437  1.00 185.06 ? 297 LYS A C   1 
ATOM   2221 O O   . LYS A 1 297 ? 115.836 79.757  91.640  1.00 185.06 ? 297 LYS A O   1 
ATOM   2222 C CB  . LYS A 1 297 ? 112.756 78.347  92.100  1.00 185.06 ? 297 LYS A CB  1 
ATOM   2223 C CG  . LYS A 1 297 ? 112.955 77.986  90.637  1.00 185.06 ? 297 LYS A CG  1 
ATOM   2224 C CD  . LYS A 1 297 ? 112.127 76.769  90.253  1.00 185.06 ? 297 LYS A CD  1 
ATOM   2225 C CE  . LYS A 1 297 ? 112.275 76.438  88.777  1.00 185.06 ? 297 LYS A CE  1 
ATOM   2226 N NZ  . LYS A 1 297 ? 111.902 77.588  87.908  1.00 185.06 ? 297 LYS A NZ  1 
ATOM   2227 N N   . LYS A 1 298 ? 115.553 78.181  93.229  1.00 190.75 ? 298 LYS A N   1 
ATOM   2228 C CA  . LYS A 1 298 ? 116.949 77.756  93.177  1.00 190.75 ? 298 LYS A CA  1 
ATOM   2229 C C   . LYS A 1 298 ? 117.287 77.129  91.829  1.00 190.75 ? 298 LYS A C   1 
ATOM   2230 O O   . LYS A 1 298 ? 118.379 77.350  91.289  1.00 190.75 ? 298 LYS A O   1 
ATOM   2231 C CB  . LYS A 1 298 ? 117.241 76.785  94.324  1.00 190.75 ? 298 LYS A CB  1 
ATOM   2232 C CG  . LYS A 1 298 ? 118.355 75.779  94.056  1.00 190.75 ? 298 LYS A CG  1 
ATOM   2233 C CD  . LYS A 1 298 ? 119.731 76.426  94.153  1.00 190.75 ? 298 LYS A CD  1 
ATOM   2234 C CE  . LYS A 1 298 ? 119.930 77.113  95.493  1.00 190.75 ? 298 LYS A CE  1 
ATOM   2235 N NZ  . LYS A 1 298 ? 121.248 77.800  95.570  1.00 190.75 ? 298 LYS A NZ  1 
ATOM   2236 N N   . ASN A 1 299 ? 116.360 76.349  91.265  1.00 188.64 ? 299 ASN A N   1 
ATOM   2237 C CA  . ASN A 1 299 ? 116.609 75.712  89.974  1.00 188.64 ? 299 ASN A CA  1 
ATOM   2238 C C   . ASN A 1 299 ? 116.757 76.736  88.856  1.00 188.64 ? 299 ASN A C   1 
ATOM   2239 O O   . ASN A 1 299 ? 117.507 76.494  87.902  1.00 188.64 ? 299 ASN A O   1 
ATOM   2240 C CB  . ASN A 1 299 ? 115.485 74.728  89.650  1.00 188.64 ? 299 ASN A CB  1 
ATOM   2241 C CG  . ASN A 1 299 ? 115.033 73.939  90.864  1.00 188.64 ? 299 ASN A CG  1 
ATOM   2242 O OD1 . ASN A 1 299 ? 115.764 73.820  91.847  1.00 188.64 ? 299 ASN A OD1 1 
ATOM   2243 N ND2 . ASN A 1 299 ? 113.823 73.395  90.801  1.00 188.64 ? 299 ASN A ND2 1 
ATOM   2244 N N   . PHE A 1 300 ? 116.044 77.860  88.960  1.00 189.15 ? 300 PHE A N   1 
ATOM   2245 C CA  . PHE A 1 300 ? 116.112 79.026  88.063  1.00 189.15 ? 300 PHE A CA  1 
ATOM   2246 C C   . PHE A 1 300 ? 116.290 78.616  86.591  1.00 189.15 ? 300 PHE A C   1 
ATOM   2247 O O   . PHE A 1 300 ? 117.245 78.970  85.902  1.00 189.15 ? 300 PHE A O   1 
ATOM   2248 C CB  . PHE A 1 300 ? 117.155 80.048  88.579  1.00 189.15 ? 300 PHE A CB  1 
ATOM   2249 C CG  . PHE A 1 300 ? 118.588 79.813  88.143  1.00 189.15 ? 300 PHE A CG  1 
ATOM   2250 C CD1 . PHE A 1 300 ? 119.330 78.757  88.640  1.00 189.15 ? 300 PHE A CD1 1 
ATOM   2251 C CD2 . PHE A 1 300 ? 119.205 80.698  87.268  1.00 189.15 ? 300 PHE A CD2 1 
ATOM   2252 C CE1 . PHE A 1 300 ? 120.637 78.556  88.239  1.00 189.15 ? 300 PHE A CE1 1 
ATOM   2253 C CE2 . PHE A 1 300 ? 120.507 80.502  86.864  1.00 189.15 ? 300 PHE A CE2 1 
ATOM   2254 C CZ  . PHE A 1 300 ? 121.228 79.434  87.355  1.00 189.15 ? 300 PHE A CZ  1 
ATOM   2255 N N   . SER A 1 301 ? 115.314 77.842  86.118  1.00 182.98 ? 301 SER A N   1 
ATOM   2256 C CA  . SER A 1 301 ? 115.362 77.306  84.762  1.00 182.98 ? 301 SER A CA  1 
ATOM   2257 C C   . SER A 1 301 ? 115.484 78.424  83.732  1.00 182.98 ? 301 SER A C   1 
ATOM   2258 O O   . SER A 1 301 ? 114.833 79.465  83.836  1.00 182.98 ? 301 SER A O   1 
ATOM   2259 C CB  . SER A 1 301 ? 114.114 76.468  84.483  1.00 182.98 ? 301 SER A CB  1 
ATOM   2260 O OG  . SER A 1 301 ? 114.099 76.007  83.142  1.00 182.98 ? 301 SER A OG  1 
ATOM   2261 N N   . ALA A 1 302 ? 116.364 78.214  82.753  1.00 178.42 ? 302 ALA A N   1 
ATOM   2262 C CA  . ALA A 1 302 ? 116.563 79.165  81.670  1.00 178.42 ? 302 ALA A CA  1 
ATOM   2263 C C   . ALA A 1 302 ? 115.791 78.800  80.411  1.00 178.42 ? 302 ALA A C   1 
ATOM   2264 O O   . ALA A 1 302 ? 115.568 79.671  79.560  1.00 178.42 ? 302 ALA A O   1 
ATOM   2265 C CB  . ALA A 1 302 ? 118.054 79.284  81.335  1.00 178.42 ? 302 ALA A CB  1 
ATOM   2266 N N   . ASP A 1 303 ? 115.387 77.535  80.273  1.00 176.78 ? 303 ASP A N   1 
ATOM   2267 C CA  . ASP A 1 303 ? 114.527 77.151  79.161  1.00 176.78 ? 303 ASP A CA  1 
ATOM   2268 C C   . ASP A 1 303 ? 113.198 77.888  79.226  1.00 176.78 ? 303 ASP A C   1 
ATOM   2269 O O   . ASP A 1 303 ? 112.665 78.316  78.196  1.00 176.78 ? 303 ASP A O   1 
ATOM   2270 C CB  . ASP A 1 303 ? 114.309 75.638  79.163  1.00 176.78 ? 303 ASP A CB  1 
ATOM   2271 C CG  . ASP A 1 303 ? 115.608 74.863  79.050  1.00 176.78 ? 303 ASP A CG  1 
ATOM   2272 O OD1 . ASP A 1 303 ? 116.680 75.501  78.986  1.00 176.78 ? 303 ASP A OD1 1 
ATOM   2273 O OD2 . ASP A 1 303 ? 115.556 73.616  79.024  1.00 176.78 ? 303 ASP A OD2 1 
ATOM   2274 N N   . VAL A 1 304 ? 112.651 78.058  80.433  1.00 174.63 ? 304 VAL A N   1 
ATOM   2275 C CA  . VAL A 1 304 ? 111.437 78.852  80.579  1.00 174.63 ? 304 VAL A CA  1 
ATOM   2276 C C   . VAL A 1 304 ? 111.723 80.319  80.274  1.00 174.63 ? 304 VAL A C   1 
ATOM   2277 O O   . VAL A 1 304 ? 110.841 81.039  79.799  1.00 174.63 ? 304 VAL A O   1 
ATOM   2278 C CB  . VAL A 1 304 ? 110.824 78.653  81.982  1.00 174.63 ? 304 VAL A CB  1 
ATOM   2279 C CG1 . VAL A 1 304 ? 111.826 78.979  83.067  1.00 174.63 ? 304 VAL A CG1 1 
ATOM   2280 C CG2 . VAL A 1 304 ? 109.540 79.462  82.154  1.00 174.63 ? 304 VAL A CG2 1 
ATOM   2281 N N   . LEU A 1 305 ? 112.954 80.786  80.509  1.00 175.28 ? 305 LEU A N   1 
ATOM   2282 C CA  . LEU A 1 305 ? 113.309 82.147  80.111  1.00 175.28 ? 305 LEU A CA  1 
ATOM   2283 C C   . LEU A 1 305 ? 113.277 82.309  78.593  1.00 175.28 ? 305 LEU A C   1 
ATOM   2284 O O   . LEU A 1 305 ? 112.745 83.302  78.079  1.00 175.28 ? 305 LEU A O   1 
ATOM   2285 C CB  . LEU A 1 305 ? 114.685 82.523  80.662  1.00 175.28 ? 305 LEU A CB  1 
ATOM   2286 C CG  . LEU A 1 305 ? 114.707 83.422  81.900  1.00 175.28 ? 305 LEU A CG  1 
ATOM   2287 C CD1 . LEU A 1 305 ? 114.307 82.643  83.142  1.00 175.28 ? 305 LEU A CD1 1 
ATOM   2288 C CD2 . LEU A 1 305 ? 116.079 84.055  82.078  1.00 175.28 ? 305 LEU A CD2 1 
ATOM   2289 N N   . LYS A 1 306 ? 113.838 81.343  77.859  1.00 172.84 ? 306 LYS A N   1 
ATOM   2290 C CA  . LYS A 1 306 ? 113.738 81.382  76.399  1.00 172.84 ? 306 LYS A CA  1 
ATOM   2291 C C   . LYS A 1 306 ? 112.288 81.284  75.936  1.00 172.84 ? 306 LYS A C   1 
ATOM   2292 O O   . LYS A 1 306 ? 111.874 81.989  75.005  1.00 172.84 ? 306 LYS A O   1 
ATOM   2293 C CB  . LYS A 1 306 ? 114.571 80.265  75.766  1.00 172.84 ? 306 LYS A CB  1 
ATOM   2294 C CG  . LYS A 1 306 ? 115.918 80.714  75.212  1.00 172.84 ? 306 LYS A CG  1 
ATOM   2295 C CD  . LYS A 1 306 ? 116.915 81.092  76.287  1.00 172.84 ? 306 LYS A CD  1 
ATOM   2296 C CE  . LYS A 1 306 ? 117.467 79.862  76.981  1.00 172.84 ? 306 LYS A CE  1 
ATOM   2297 N NZ  . LYS A 1 306 ? 118.274 80.227  78.173  1.00 172.84 ? 306 LYS A NZ  1 
ATOM   2298 N N   . ASN A 1 307 ? 111.502 80.412  76.572  1.00 171.97 ? 307 ASN A N   1 
ATOM   2299 C CA  . ASN A 1 307 ? 110.101 80.276  76.189  1.00 171.97 ? 307 ASN A CA  1 
ATOM   2300 C C   . ASN A 1 307 ? 109.307 81.538  76.499  1.00 171.97 ? 307 ASN A C   1 
ATOM   2301 O O   . ASN A 1 307 ? 108.379 81.873  75.763  1.00 171.97 ? 307 ASN A O   1 
ATOM   2302 C CB  . ASN A 1 307 ? 109.479 79.064  76.880  1.00 171.97 ? 307 ASN A CB  1 
ATOM   2303 C CG  . ASN A 1 307 ? 110.186 77.770  76.530  1.00 171.97 ? 307 ASN A CG  1 
ATOM   2304 O OD1 . ASN A 1 307 ? 111.088 77.750  75.693  1.00 171.97 ? 307 ASN A OD1 1 
ATOM   2305 N ND2 . ASN A 1 307 ? 109.780 76.680  77.171  1.00 171.97 ? 307 ASN A ND2 1 
ATOM   2306 N N   . ALA A 1 308 ? 109.683 82.278  77.543  1.00 162.45 ? 308 ALA A N   1 
ATOM   2307 C CA  . ALA A 1 308 ? 109.013 83.537  77.847  1.00 162.45 ? 308 ALA A CA  1 
ATOM   2308 C C   . ALA A 1 308 ? 109.444 84.646  76.899  1.00 162.45 ? 308 ALA A C   1 
ATOM   2309 O O   . ALA A 1 308 ? 108.640 85.529  76.578  1.00 162.45 ? 308 ALA A O   1 
ATOM   2310 C CB  . ALA A 1 308 ? 109.286 83.947  79.295  1.00 162.45 ? 308 ALA A CB  1 
ATOM   2311 N N   . GLN A 1 309 ? 110.702 84.622  76.453  1.00 160.76 ? 309 GLN A N   1 
ATOM   2312 C CA  . GLN A 1 309 ? 111.127 85.542  75.402  1.00 160.76 ? 309 GLN A CA  1 
ATOM   2313 C C   . GLN A 1 309 ? 110.339 85.296  74.120  1.00 160.76 ? 309 GLN A C   1 
ATOM   2314 O O   . GLN A 1 309 ? 109.913 86.244  73.451  1.00 160.76 ? 309 GLN A O   1 
ATOM   2315 C CB  . GLN A 1 309 ? 112.637 85.408  75.169  1.00 160.76 ? 309 GLN A CB  1 
ATOM   2316 C CG  . GLN A 1 309 ? 113.162 85.906  73.819  1.00 160.76 ? 309 GLN A CG  1 
ATOM   2317 C CD  . GLN A 1 309 ? 113.092 84.855  72.723  1.00 160.76 ? 309 GLN A CD  1 
ATOM   2318 O OE1 . GLN A 1 309 ? 113.414 83.688  72.945  1.00 160.76 ? 309 GLN A OE1 1 
ATOM   2319 N NE2 . GLN A 1 309 ? 112.659 85.266  71.537  1.00 160.76 ? 309 GLN A NE2 1 
ATOM   2320 N N   . ASP A 1 310 ? 110.133 84.025  73.768  1.00 157.35 ? 310 ASP A N   1 
ATOM   2321 C CA  . ASP A 1 310 ? 109.264 83.702  72.638  1.00 157.35 ? 310 ASP A CA  1 
ATOM   2322 C C   . ASP A 1 310 ? 107.813 84.074  72.921  1.00 157.35 ? 310 ASP A C   1 
ATOM   2323 O O   . ASP A 1 310 ? 107.071 84.437  72.000  1.00 157.35 ? 310 ASP A O   1 
ATOM   2324 C CB  . ASP A 1 310 ? 109.363 82.214  72.303  1.00 157.35 ? 310 ASP A CB  1 
ATOM   2325 C CG  . ASP A 1 310 ? 110.325 81.934  71.167  1.00 157.35 ? 310 ASP A CG  1 
ATOM   2326 O OD1 . ASP A 1 310 ? 110.742 82.895  70.489  1.00 157.35 ? 310 ASP A OD1 1 
ATOM   2327 O OD2 . ASP A 1 310 ? 110.660 80.750  70.951  1.00 157.35 ? 310 ASP A OD2 1 
ATOM   2328 N N   . LYS A 1 311 ? 107.398 83.985  74.184  1.00 154.49 ? 311 LYS A N   1 
ATOM   2329 C CA  . LYS A 1 311 ? 106.000 84.172  74.550  1.00 154.49 ? 311 LYS A CA  1 
ATOM   2330 C C   . LYS A 1 311 ? 105.597 85.640  74.503  1.00 154.49 ? 311 LYS A C   1 
ATOM   2331 O O   . LYS A 1 311 ? 104.478 85.968  74.091  1.00 154.49 ? 311 LYS A O   1 
ATOM   2332 C CB  . LYS A 1 311 ? 105.769 83.567  75.935  1.00 154.49 ? 311 LYS A CB  1 
ATOM   2333 C CG  . LYS A 1 311 ? 104.791 84.292  76.828  1.00 154.49 ? 311 LYS A CG  1 
ATOM   2334 C CD  . LYS A 1 311 ? 104.348 83.368  77.950  1.00 154.49 ? 311 LYS A CD  1 
ATOM   2335 C CE  . LYS A 1 311 ? 103.542 84.107  78.991  1.00 154.49 ? 311 LYS A CE  1 
ATOM   2336 N NZ  . LYS A 1 311 ? 102.958 83.189  80.008  1.00 154.49 ? 311 LYS A NZ  1 
ATOM   2337 N N   . GLY A 1 312 ? 106.491 86.536  74.906  1.00 146.78 ? 312 GLY A N   1 
ATOM   2338 C CA  . GLY A 1 312 ? 106.178 87.950  74.876  1.00 146.78 ? 312 GLY A CA  1 
ATOM   2339 C C   . GLY A 1 312 ? 106.349 88.660  76.202  1.00 146.78 ? 312 GLY A C   1 
ATOM   2340 O O   . GLY A 1 312 ? 105.715 89.690  76.449  1.00 146.78 ? 312 GLY A O   1 
ATOM   2341 N N   . VAL A 1 313 ? 107.207 88.122  77.064  1.00 148.27 ? 313 VAL A N   1 
ATOM   2342 C CA  . VAL A 1 313 ? 107.496 88.713  78.364  1.00 148.27 ? 313 VAL A CA  1 
ATOM   2343 C C   . VAL A 1 313 ? 108.962 89.122  78.376  1.00 148.27 ? 313 VAL A C   1 
ATOM   2344 O O   . VAL A 1 313 ? 109.850 88.275  78.216  1.00 148.27 ? 313 VAL A O   1 
ATOM   2345 C CB  . VAL A 1 313 ? 107.183 87.741  79.512  1.00 148.27 ? 313 VAL A CB  1 
ATOM   2346 C CG1 . VAL A 1 313 ? 107.824 88.216  80.799  1.00 148.27 ? 313 VAL A CG1 1 
ATOM   2347 C CG2 . VAL A 1 313 ? 105.678 87.590  79.683  1.00 148.27 ? 313 VAL A CG2 1 
ATOM   2348 N N   . LEU A 1 314 ? 109.213 90.417  78.553  1.00 147.47 ? 314 LEU A N   1 
ATOM   2349 C CA  . LEU A 1 314 ? 110.580 90.914  78.608  1.00 147.47 ? 314 LEU A CA  1 
ATOM   2350 C C   . LEU A 1 314 ? 111.181 90.616  79.977  1.00 147.47 ? 314 LEU A C   1 
ATOM   2351 O O   . LEU A 1 314 ? 110.507 90.723  81.005  1.00 147.47 ? 314 LEU A O   1 
ATOM   2352 C CB  . LEU A 1 314 ? 110.605 92.419  78.322  1.00 147.47 ? 314 LEU A CB  1 
ATOM   2353 C CG  . LEU A 1 314 ? 111.880 93.275  78.325  1.00 147.47 ? 314 LEU A CG  1 
ATOM   2354 C CD1 . LEU A 1 314 ? 113.115 92.519  77.850  1.00 147.47 ? 314 LEU A CD1 1 
ATOM   2355 C CD2 . LEU A 1 314 ? 111.678 94.536  77.501  1.00 147.47 ? 314 LEU A CD2 1 
ATOM   2356 N N   . VAL A 1 315 ? 112.455 90.243  79.984  1.00 160.19 ? 315 VAL A N   1 
ATOM   2357 C CA  . VAL A 1 315 ? 113.183 89.899  81.199  1.00 160.19 ? 315 VAL A CA  1 
ATOM   2358 C C   . VAL A 1 315 ? 113.966 91.126  81.647  1.00 160.19 ? 315 VAL A C   1 
ATOM   2359 O O   . VAL A 1 315 ? 114.607 91.794  80.826  1.00 160.19 ? 315 VAL A O   1 
ATOM   2360 C CB  . VAL A 1 315 ? 114.117 88.702  80.968  1.00 160.19 ? 315 VAL A CB  1 
ATOM   2361 C CG1 . VAL A 1 315 ? 113.342 87.397  81.059  1.00 160.19 ? 315 VAL A CG1 1 
ATOM   2362 C CG2 . VAL A 1 315 ? 114.796 88.818  79.610  1.00 160.19 ? 315 VAL A CG2 1 
ATOM   2363 N N   . ALA A 1 316 ? 113.912 91.443  82.941  1.00 160.57 ? 316 ALA A N   1 
ATOM   2364 C CA  . ALA A 1 316 ? 114.710 92.535  83.473  1.00 160.57 ? 316 ALA A CA  1 
ATOM   2365 C C   . ALA A 1 316 ? 115.076 92.217  84.912  1.00 160.57 ? 316 ALA A C   1 
ATOM   2366 O O   . ALA A 1 316 ? 114.457 91.367  85.555  1.00 160.57 ? 316 ALA A O   1 
ATOM   2367 C CB  . ALA A 1 316 ? 113.961 93.871  83.392  1.00 160.57 ? 316 ALA A CB  1 
ATOM   2368 N N   . THR A 1 317 ? 116.078 92.925  85.422  1.00 164.05 ? 317 THR A N   1 
ATOM   2369 C CA  . THR A 1 317 ? 116.459 92.765  86.815  1.00 164.05 ? 317 THR A CA  1 
ATOM   2370 C C   . THR A 1 317 ? 115.457 93.488  87.714  1.00 164.05 ? 317 THR A C   1 
ATOM   2371 O O   . THR A 1 317 ? 114.467 94.063  87.251  1.00 164.05 ? 317 THR A O   1 
ATOM   2372 C CB  . THR A 1 317 ? 117.879 93.279  87.042  1.00 164.05 ? 317 THR A CB  1 
ATOM   2373 O OG1 . THR A 1 317 ? 117.966 94.648  86.624  1.00 164.05 ? 317 THR A OG1 1 
ATOM   2374 C CG2 . THR A 1 317 ? 118.874 92.448  86.248  1.00 164.05 ? 317 THR A CG2 1 
ATOM   2375 N N   . LEU A 1 318 ? 115.711 93.449  89.024  1.00 164.11 ? 318 LEU A N   1 
ATOM   2376 C CA  . LEU A 1 318 ? 114.822 94.117  89.970  1.00 164.11 ? 318 LEU A CA  1 
ATOM   2377 C C   . LEU A 1 318 ? 114.807 95.625  89.754  1.00 164.11 ? 318 LEU A C   1 
ATOM   2378 O O   . LEU A 1 318 ? 113.756 96.265  89.878  1.00 164.11 ? 318 LEU A O   1 
ATOM   2379 C CB  . LEU A 1 318 ? 115.221 93.781  91.405  1.00 164.11 ? 318 LEU A CB  1 
ATOM   2380 C CG  . LEU A 1 318 ? 114.042 93.769  92.379  1.00 164.11 ? 318 LEU A CG  1 
ATOM   2381 C CD1 . LEU A 1 318 ? 113.162 92.553  92.156  1.00 164.11 ? 318 LEU A CD1 1 
ATOM   2382 C CD2 . LEU A 1 318 ? 114.537 93.821  93.817  1.00 164.11 ? 318 LEU A CD2 1 
ATOM   2383 N N   . ALA A 1 319 ? 115.965 96.212  89.447  1.00 161.01 ? 319 ALA A N   1 
ATOM   2384 C CA  . ALA A 1 319 ? 115.998 97.628  89.100  1.00 161.01 ? 319 ALA A CA  1 
ATOM   2385 C C   . ALA A 1 319 ? 115.213 97.896  87.823  1.00 161.01 ? 319 ALA A C   1 
ATOM   2386 O O   . ALA A 1 319 ? 114.495 98.898  87.722  1.00 161.01 ? 319 ALA A O   1 
ATOM   2387 C CB  . ALA A 1 319 ? 117.444 98.101  88.954  1.00 161.01 ? 319 ALA A CB  1 
ATOM   2388 N N   . GLY A 1 320 ? 115.331 97.007  86.839  1.00 156.35 ? 320 GLY A N   1 
ATOM   2389 C CA  . GLY A 1 320 ? 114.604 97.145  85.594  1.00 156.35 ? 320 GLY A CA  1 
ATOM   2390 C C   . GLY A 1 320 ? 115.476 97.631  84.456  1.00 156.35 ? 320 GLY A C   1 
ATOM   2391 O O   . GLY A 1 320 ? 115.765 98.827  84.360  1.00 156.35 ? 320 GLY A O   1 
ATOM   2392 N N   . ASP A 1 321 ? 115.899 96.711  83.591  1.00 157.05 ? 321 ASP A N   1 
ATOM   2393 C CA  . ASP A 1 321 ? 116.738 97.022  82.441  1.00 157.05 ? 321 ASP A CA  1 
ATOM   2394 C C   . ASP A 1 321 ? 116.817 95.793  81.550  1.00 157.05 ? 321 ASP A C   1 
ATOM   2395 O O   . ASP A 1 321 ? 116.763 94.659  82.035  1.00 157.05 ? 321 ASP A O   1 
ATOM   2396 C CB  . ASP A 1 321 ? 118.149 97.454  82.864  1.00 157.05 ? 321 ASP A CB  1 
ATOM   2397 C CG  . ASP A 1 321 ? 118.671 96.667  84.051  1.00 157.05 ? 321 ASP A CG  1 
ATOM   2398 O OD1 . ASP A 1 321 ? 118.126 95.580  84.338  1.00 157.05 ? 321 ASP A OD1 1 
ATOM   2399 O OD2 . ASP A 1 321 ? 119.631 97.135  84.697  1.00 157.05 ? 321 ASP A OD2 1 
ATOM   2400 N N   . VAL A 1 322 ? 116.947 96.027  80.244  1.00 165.22 ? 322 VAL A N   1 
ATOM   2401 C CA  . VAL A 1 322 ? 117.166 94.924  79.320  1.00 165.22 ? 322 VAL A CA  1 
ATOM   2402 C C   . VAL A 1 322 ? 118.546 94.328  79.571  1.00 165.22 ? 322 VAL A C   1 
ATOM   2403 O O   . VAL A 1 322 ? 119.504 95.039  79.911  1.00 165.22 ? 322 VAL A O   1 
ATOM   2404 C CB  . VAL A 1 322 ? 116.981 95.387  77.862  1.00 165.22 ? 322 VAL A CB  1 
ATOM   2405 C CG1 . VAL A 1 322 ? 118.203 96.138  77.345  1.00 165.22 ? 322 VAL A CG1 1 
ATOM   2406 C CG2 . VAL A 1 322 ? 116.659 94.200  76.965  1.00 165.22 ? 322 VAL A CG2 1 
ATOM   2407 N N   . MET A 1 323 ? 118.642 93.005  79.469  1.00 179.38 ? 323 MET A N   1 
ATOM   2408 C CA  . MET A 1 323 ? 119.868 92.290  79.784  1.00 179.38 ? 323 MET A CA  1 
ATOM   2409 C C   . MET A 1 323 ? 120.155 91.240  78.719  1.00 179.38 ? 323 MET A C   1 
ATOM   2410 O O   . MET A 1 323 ? 119.246 90.747  78.045  1.00 179.38 ? 323 MET A O   1 
ATOM   2411 C CB  . MET A 1 323 ? 119.791 91.663  81.189  1.00 179.38 ? 323 MET A CB  1 
ATOM   2412 C CG  . MET A 1 323 ? 118.431 91.086  81.553  1.00 179.38 ? 323 MET A CG  1 
ATOM   2413 S SD  . MET A 1 323 ? 118.093 89.475  80.834  1.00 179.38 ? 323 MET A SD  1 
ATOM   2414 C CE  . MET A 1 323 ? 119.286 88.468  81.707  1.00 179.38 ? 323 MET A CE  1 
ATOM   2415 N N   . ASP A 1 324 ? 121.438 90.917  78.573  1.00 191.67 ? 324 ASP A N   1 
ATOM   2416 C CA  . ASP A 1 324 ? 121.897 90.104  77.455  1.00 191.67 ? 324 ASP A CA  1 
ATOM   2417 C C   . ASP A 1 324 ? 121.357 88.678  77.566  1.00 191.67 ? 324 ASP A C   1 
ATOM   2418 O O   . ASP A 1 324 ? 121.310 88.114  78.665  1.00 191.67 ? 324 ASP A O   1 
ATOM   2419 C CB  . ASP A 1 324 ? 123.426 90.089  77.413  1.00 191.67 ? 324 ASP A CB  1 
ATOM   2420 C CG  . ASP A 1 324 ? 123.975 89.542  76.108  1.00 191.67 ? 324 ASP A CG  1 
ATOM   2421 O OD1 . ASP A 1 324 ? 123.847 88.325  75.861  1.00 191.67 ? 324 ASP A OD1 1 
ATOM   2422 O OD2 . ASP A 1 324 ? 124.543 90.334  75.327  1.00 191.67 ? 324 ASP A OD2 1 
ATOM   2423 N N   . PRO A 1 325 ? 120.943 88.072  76.446  1.00 193.48 ? 325 PRO A N   1 
ATOM   2424 C CA  . PRO A 1 325 ? 120.476 86.675  76.492  1.00 193.48 ? 325 PRO A CA  1 
ATOM   2425 C C   . PRO A 1 325 ? 121.525 85.694  76.983  1.00 193.48 ? 325 PRO A C   1 
ATOM   2426 O O   . PRO A 1 325 ? 121.168 84.668  77.576  1.00 193.48 ? 325 PRO A O   1 
ATOM   2427 C CB  . PRO A 1 325 ? 120.083 86.393  75.035  1.00 193.48 ? 325 PRO A CB  1 
ATOM   2428 C CG  . PRO A 1 325 ? 119.766 87.733  74.465  1.00 193.48 ? 325 PRO A CG  1 
ATOM   2429 C CD  . PRO A 1 325 ? 120.708 88.693  75.132  1.00 193.48 ? 325 PRO A CD  1 
ATOM   2430 N N   . ALA A 1 326 ? 122.812 85.974  76.758  1.00 194.25 ? 326 ALA A N   1 
ATOM   2431 C CA  . ALA A 1 326 ? 123.861 85.114  77.293  1.00 194.25 ? 326 ALA A CA  1 
ATOM   2432 C C   . ALA A 1 326 ? 123.872 85.108  78.815  1.00 194.25 ? 326 ALA A C   1 
ATOM   2433 O O   . ALA A 1 326 ? 124.412 84.172  79.416  1.00 194.25 ? 326 ALA A O   1 
ATOM   2434 C CB  . ALA A 1 326 ? 125.228 85.547  76.763  1.00 194.25 ? 326 ALA A CB  1 
ATOM   2435 N N   . GLN A 1 327 ? 123.288 86.126  79.450  1.00 195.31 ? 327 GLN A N   1 
ATOM   2436 C CA  . GLN A 1 327 ? 123.138 86.134  80.898  1.00 195.31 ? 327 GLN A CA  1 
ATOM   2437 C C   . GLN A 1 327 ? 122.089 85.144  81.388  1.00 195.31 ? 327 GLN A C   1 
ATOM   2438 O O   . GLN A 1 327 ? 121.997 84.927  82.601  1.00 195.31 ? 327 GLN A O   1 
ATOM   2439 C CB  . GLN A 1 327 ? 122.778 87.540  81.383  1.00 195.31 ? 327 GLN A CB  1 
ATOM   2440 C CG  . GLN A 1 327 ? 123.787 88.634  81.036  1.00 195.31 ? 327 GLN A CG  1 
ATOM   2441 C CD  . GLN A 1 327 ? 125.213 88.130  80.919  1.00 195.31 ? 327 GLN A CD  1 
ATOM   2442 O OE1 . GLN A 1 327 ? 125.813 88.182  79.846  1.00 195.31 ? 327 GLN A OE1 1 
ATOM   2443 N NE2 . GLN A 1 327 ? 125.776 87.672  82.034  1.00 195.31 ? 327 GLN A NE2 1 
ATOM   2444 N N   . PHE A 1 328 ? 121.294 84.555  80.488  1.00 193.43 ? 328 PHE A N   1 
ATOM   2445 C CA  . PHE A 1 328 ? 120.273 83.597  80.911  1.00 193.43 ? 328 PHE A CA  1 
ATOM   2446 C C   . PHE A 1 328 ? 120.898 82.373  81.571  1.00 193.43 ? 328 PHE A C   1 
ATOM   2447 O O   . PHE A 1 328 ? 120.404 81.892  82.597  1.00 193.43 ? 328 PHE A O   1 
ATOM   2448 C CB  . PHE A 1 328 ? 119.408 83.164  79.722  1.00 193.43 ? 328 PHE A CB  1 
ATOM   2449 C CG  . PHE A 1 328 ? 118.587 84.273  79.102  1.00 193.43 ? 328 PHE A CG  1 
ATOM   2450 C CD1 . PHE A 1 328 ? 118.521 85.534  79.671  1.00 193.43 ? 328 PHE A CD1 1 
ATOM   2451 C CD2 . PHE A 1 328 ? 117.884 84.040  77.932  1.00 193.43 ? 328 PHE A CD2 1 
ATOM   2452 C CE1 . PHE A 1 328 ? 117.767 86.534  79.086  1.00 193.43 ? 328 PHE A CE1 1 
ATOM   2453 C CE2 . PHE A 1 328 ? 117.130 85.037  77.344  1.00 193.43 ? 328 PHE A CE2 1 
ATOM   2454 C CZ  . PHE A 1 328 ? 117.072 86.285  77.922  1.00 193.43 ? 328 PHE A CZ  1 
ATOM   2455 N N   . SER A 1 329 ? 121.982 81.851  80.992  1.00 195.11 ? 329 SER A N   1 
ATOM   2456 C CA  . SER A 1 329 ? 122.578 80.624  81.511  1.00 195.11 ? 329 SER A CA  1 
ATOM   2457 C C   . SER A 1 329 ? 123.316 80.867  82.823  1.00 195.11 ? 329 SER A C   1 
ATOM   2458 O O   . SER A 1 329 ? 123.276 80.025  83.727  1.00 195.11 ? 329 SER A O   1 
ATOM   2459 C CB  . SER A 1 329 ? 123.521 80.020  80.470  1.00 195.11 ? 329 SER A CB  1 
ATOM   2460 O OG  . SER A 1 329 ? 124.514 80.951  80.079  1.00 195.11 ? 329 SER A OG  1 
ATOM   2461 N N   . THR A 1 330 ? 123.994 82.009  82.948  1.00 197.50 ? 330 THR A N   1 
ATOM   2462 C CA  . THR A 1 330 ? 124.854 82.291  84.091  1.00 197.50 ? 330 THR A CA  1 
ATOM   2463 C C   . THR A 1 330 ? 124.207 83.238  85.098  1.00 197.50 ? 330 THR A C   1 
ATOM   2464 O O   . THR A 1 330 ? 124.913 83.975  85.795  1.00 197.50 ? 330 THR A O   1 
ATOM   2465 C CB  . THR A 1 330 ? 126.192 82.858  83.617  1.00 197.50 ? 330 THR A CB  1 
ATOM   2466 O OG1 . THR A 1 330 ? 125.971 84.091  82.920  1.00 197.50 ? 330 THR A OG1 1 
ATOM   2467 C CG2 . THR A 1 330 ? 126.888 81.874  82.689  1.00 197.50 ? 330 THR A CG2 1 
ATOM   2468 N N   . LEU A 1 331 ? 122.880 83.237  85.188  1.00 194.20 ? 331 LEU A N   1 
ATOM   2469 C CA  . LEU A 1 331 ? 122.201 84.066  86.171  1.00 194.20 ? 331 LEU A CA  1 
ATOM   2470 C C   . LEU A 1 331 ? 122.401 83.508  87.578  1.00 194.20 ? 331 LEU A C   1 
ATOM   2471 O O   . LEU A 1 331 ? 122.780 82.351  87.773  1.00 194.20 ? 331 LEU A O   1 
ATOM   2472 C CB  . LEU A 1 331 ? 120.708 84.167  85.854  1.00 194.20 ? 331 LEU A CB  1 
ATOM   2473 C CG  . LEU A 1 331 ? 120.223 85.500  85.279  1.00 194.20 ? 331 LEU A CG  1 
ATOM   2474 C CD1 . LEU A 1 331 ? 118.705 85.529  85.192  1.00 194.20 ? 331 LEU A CD1 1 
ATOM   2475 C CD2 . LEU A 1 331 ? 120.738 86.667  86.109  1.00 194.20 ? 331 LEU A CD2 1 
ATOM   2476 N N   . LYS A 1 332 ? 122.163 84.361  88.566  1.00 189.61 ? 332 LYS A N   1 
ATOM   2477 C CA  . LYS A 1 332 ? 122.251 83.938  89.960  1.00 189.61 ? 332 LYS A CA  1 
ATOM   2478 C C   . LYS A 1 332 ? 120.994 83.169  90.351  1.00 189.61 ? 332 LYS A C   1 
ATOM   2479 O O   . LYS A 1 332 ? 119.882 83.653  90.116  1.00 189.61 ? 332 LYS A O   1 
ATOM   2480 C CB  . LYS A 1 332 ? 122.439 85.141  90.878  1.00 189.61 ? 332 LYS A CB  1 
ATOM   2481 C CG  . LYS A 1 332 ? 123.791 85.815  90.732  1.00 189.61 ? 332 LYS A CG  1 
ATOM   2482 C CD  . LYS A 1 332 ? 124.920 84.835  91.008  1.00 189.61 ? 332 LYS A CD  1 
ATOM   2483 C CE  . LYS A 1 332 ? 126.278 85.480  90.793  1.00 189.61 ? 332 LYS A CE  1 
ATOM   2484 N NZ  . LYS A 1 332 ? 127.389 84.534  91.085  1.00 189.61 ? 332 LYS A NZ  1 
ATOM   2485 N N   . PRO A 1 333 ? 121.128 81.969  90.919  1.00 191.51 ? 333 PRO A N   1 
ATOM   2486 C CA  . PRO A 1 333 ? 119.940 81.211  91.331  1.00 191.51 ? 333 PRO A CA  1 
ATOM   2487 C C   . PRO A 1 333 ? 119.156 81.939  92.413  1.00 191.51 ? 333 PRO A C   1 
ATOM   2488 O O   . PRO A 1 333 ? 119.732 82.570  93.303  1.00 191.51 ? 333 PRO A O   1 
ATOM   2489 C CB  . PRO A 1 333 ? 120.524 79.893  91.856  1.00 191.51 ? 333 PRO A CB  1 
ATOM   2490 C CG  . PRO A 1 333 ? 121.901 79.815  91.271  1.00 191.51 ? 333 PRO A CG  1 
ATOM   2491 C CD  . PRO A 1 333 ? 122.374 81.230  91.178  1.00 191.51 ? 333 PRO A CD  1 
ATOM   2492 N N   . ALA A 1 334 ? 117.828 81.833  92.327  1.00 188.98 ? 334 ALA A N   1 
ATOM   2493 C CA  . ALA A 1 334 ? 116.902 82.414  93.302  1.00 188.98 ? 334 ALA A CA  1 
ATOM   2494 C C   . ALA A 1 334 ? 117.136 83.914  93.482  1.00 188.98 ? 334 ALA A C   1 
ATOM   2495 O O   . ALA A 1 334 ? 117.201 84.430  94.600  1.00 188.98 ? 334 ALA A O   1 
ATOM   2496 C CB  . ALA A 1 334 ? 116.989 81.680  94.642  1.00 188.98 ? 334 ALA A CB  1 
ATOM   2497 N N   . GLU A 1 335 ? 117.262 84.619  92.362  1.00 188.91 ? 335 GLU A N   1 
ATOM   2498 C CA  . GLU A 1 335 ? 117.470 86.061  92.358  1.00 188.91 ? 335 GLU A CA  1 
ATOM   2499 C C   . GLU A 1 335 ? 116.216 86.750  91.838  1.00 188.91 ? 335 GLU A C   1 
ATOM   2500 O O   . GLU A 1 335 ? 115.694 86.382  90.780  1.00 188.91 ? 335 GLU A O   1 
ATOM   2501 C CB  . GLU A 1 335 ? 118.679 86.442  91.503  1.00 188.91 ? 335 GLU A CB  1 
ATOM   2502 C CG  . GLU A 1 335 ? 119.003 87.926  91.529  1.00 188.91 ? 335 GLU A CG  1 
ATOM   2503 C CD  . GLU A 1 335 ? 120.024 88.320  90.483  1.00 188.91 ? 335 GLU A CD  1 
ATOM   2504 O OE1 . GLU A 1 335 ? 120.437 87.443  89.696  1.00 188.91 ? 335 GLU A OE1 1 
ATOM   2505 O OE2 . GLU A 1 335 ? 120.410 89.507  90.444  1.00 188.91 ? 335 GLU A OE2 1 
ATOM   2506 N N   . SER A 1 336 ? 115.737 87.745  92.580  1.00 175.13 ? 336 SER A N   1 
ATOM   2507 C CA  . SER A 1 336 ? 114.503 88.429  92.219  1.00 175.13 ? 336 SER A CA  1 
ATOM   2508 C C   . SER A 1 336 ? 114.688 89.271  90.960  1.00 175.13 ? 336 SER A C   1 
ATOM   2509 O O   . SER A 1 336 ? 115.692 89.971  90.802  1.00 175.13 ? 336 SER A O   1 
ATOM   2510 C CB  . SER A 1 336 ? 114.029 89.302  93.381  1.00 175.13 ? 336 SER A CB  1 
ATOM   2511 O OG  . SER A 1 336 ? 112.620 89.451  93.372  1.00 175.13 ? 336 SER A OG  1 
ATOM   2512 N N   . VAL A 1 337 ? 113.703 89.199  90.059  1.00 170.72 ? 337 VAL A N   1 
ATOM   2513 C CA  . VAL A 1 337 ? 113.745 89.878  88.767  1.00 170.72 ? 337 VAL A CA  1 
ATOM   2514 C C   . VAL A 1 337 ? 112.383 90.507  88.495  1.00 170.72 ? 337 VAL A C   1 
ATOM   2515 O O   . VAL A 1 337 ? 111.390 90.205  89.155  1.00 170.72 ? 337 VAL A O   1 
ATOM   2516 C CB  . VAL A 1 337 ? 114.130 88.922  87.618  1.00 170.72 ? 337 VAL A CB  1 
ATOM   2517 C CG1 . VAL A 1 337 ? 115.587 88.497  87.735  1.00 170.72 ? 337 VAL A CG1 1 
ATOM   2518 C CG2 . VAL A 1 337 ? 113.211 87.712  87.602  1.00 170.72 ? 337 VAL A CG2 1 
ATOM   2519 N N   . THR A 1 338 ? 112.337 91.386  87.496  1.00 162.04 ? 338 THR A N   1 
ATOM   2520 C CA  . THR A 1 338 ? 111.116 92.089  87.128  1.00 162.04 ? 338 THR A CA  1 
ATOM   2521 C C   . THR A 1 338 ? 110.773 91.833  85.665  1.00 162.04 ? 338 THR A C   1 
ATOM   2522 O O   . THR A 1 338 ? 111.651 91.845  84.793  1.00 162.04 ? 338 THR A O   1 
ATOM   2523 C CB  . THR A 1 338 ? 111.248 93.595  87.377  1.00 162.04 ? 338 THR A CB  1 
ATOM   2524 O OG1 . THR A 1 338 ? 111.858 93.818  88.654  1.00 162.04 ? 338 THR A OG1 1 
ATOM   2525 C CG2 . THR A 1 338 ? 109.883 94.259  87.355  1.00 162.04 ? 338 THR A CG2 1 
ATOM   2526 N N   . LEU A 1 339 ? 109.488 91.617  85.399  1.00 155.11 ? 339 LEU A N   1 
ATOM   2527 C CA  . LEU A 1 339 ? 109.013 91.326  84.056  1.00 155.11 ? 339 LEU A CA  1 
ATOM   2528 C C   . LEU A 1 339 ? 107.817 92.204  83.721  1.00 155.11 ? 339 LEU A C   1 
ATOM   2529 O O   . LEU A 1 339 ? 107.032 92.581  84.597  1.00 155.11 ? 339 LEU A O   1 
ATOM   2530 C CB  . LEU A 1 339 ? 108.624 89.847  83.908  1.00 155.11 ? 339 LEU A CB  1 
ATOM   2531 C CG  . LEU A 1 339 ? 109.545 88.797  84.533  1.00 155.11 ? 339 LEU A CG  1 
ATOM   2532 C CD1 . LEU A 1 339 ? 108.905 87.418  84.474  1.00 155.11 ? 339 LEU A CD1 1 
ATOM   2533 C CD2 . LEU A 1 339 ? 110.902 88.786  83.851  1.00 155.11 ? 339 LEU A CD2 1 
ATOM   2534 N N   . VAL A 1 340 ? 107.685 92.519  82.434  1.00 144.18 ? 340 VAL A N   1 
ATOM   2535 C CA  . VAL A 1 340 ? 106.549 93.263  81.906  1.00 144.18 ? 340 VAL A CA  1 
ATOM   2536 C C   . VAL A 1 340 ? 105.735 92.325  81.028  1.00 144.18 ? 340 VAL A C   1 
ATOM   2537 O O   . VAL A 1 340 ? 106.272 91.388  80.425  1.00 144.18 ? 340 VAL A O   1 
ATOM   2538 C CB  . VAL A 1 340 ? 106.984 94.506  81.098  1.00 144.18 ? 340 VAL A CB  1 
ATOM   2539 C CG1 . VAL A 1 340 ? 107.346 95.652  82.017  1.00 144.18 ? 340 VAL A CG1 1 
ATOM   2540 C CG2 . VAL A 1 340 ? 108.148 94.166  80.197  1.00 144.18 ? 340 VAL A CG2 1 
ATOM   2541 N N   . GLY A 1 341 ? 104.435 92.572  80.958  1.00 145.35 ? 341 GLY A N   1 
ATOM   2542 C CA  . GLY A 1 341 ? 103.616 91.758  80.075  1.00 145.35 ? 341 GLY A CA  1 
ATOM   2543 C C   . GLY A 1 341 ? 102.139 91.870  80.418  1.00 145.35 ? 341 GLY A C   1 
ATOM   2544 O O   . GLY A 1 341 ? 101.683 92.892  80.931  1.00 145.35 ? 341 GLY A O   1 
ATOM   2545 N N   . GLN A 1 342 ? 101.419 90.795  80.112  1.00 154.89 ? 342 GLN A N   1 
ATOM   2546 C CA  . GLN A 1 342 ? 99.978  90.719  80.287  1.00 154.89 ? 342 GLN A CA  1 
ATOM   2547 C C   . GLN A 1 342 ? 99.643  90.537  81.771  1.00 154.89 ? 342 GLN A C   1 
ATOM   2548 O O   . GLN A 1 342 ? 100.506 90.229  82.597  1.00 154.89 ? 342 GLN A O   1 
ATOM   2549 C CB  . GLN A 1 342 ? 99.423  89.586  79.414  1.00 154.89 ? 342 GLN A CB  1 
ATOM   2550 C CG  . GLN A 1 342 ? 97.911  89.394  79.403  1.00 154.89 ? 342 GLN A CG  1 
ATOM   2551 C CD  . GLN A 1 342 ? 97.487  88.175  78.616  1.00 154.89 ? 342 GLN A CD  1 
ATOM   2552 O OE1 . GLN A 1 342 ? 98.142  87.133  78.662  1.00 154.89 ? 342 GLN A OE1 1 
ATOM   2553 N NE2 . GLN A 1 342 ? 96.386  88.297  77.884  1.00 154.89 ? 342 GLN A NE2 1 
ATOM   2554 N N   . LYS A 1 343 ? 98.367  90.759  82.106  1.00 153.21 ? 343 LYS A N   1 
ATOM   2555 C CA  . LYS A 1 343 ? 97.915  90.721  83.495  1.00 153.21 ? 343 LYS A CA  1 
ATOM   2556 C C   . LYS A 1 343 ? 98.197  89.370  84.147  1.00 153.21 ? 343 LYS A C   1 
ATOM   2557 O O   . LYS A 1 343 ? 98.695  89.308  85.277  1.00 153.21 ? 343 LYS A O   1 
ATOM   2558 C CB  . LYS A 1 343 ? 96.421  91.040  83.550  1.00 153.21 ? 343 LYS A CB  1 
ATOM   2559 C CG  . LYS A 1 343 ? 95.763  90.787  84.894  1.00 153.21 ? 343 LYS A CG  1 
ATOM   2560 C CD  . LYS A 1 343 ? 96.323  91.703  85.967  1.00 153.21 ? 343 LYS A CD  1 
ATOM   2561 C CE  . LYS A 1 343 ? 95.910  93.143  85.713  1.00 153.21 ? 343 LYS A CE  1 
ATOM   2562 N NZ  . LYS A 1 343 ? 94.430  93.305  85.732  1.00 153.21 ? 343 LYS A NZ  1 
ATOM   2563 N N   . ASP A 1 344 ? 97.889  88.274  83.449  1.00 158.87 ? 344 ASP A N   1 
ATOM   2564 C CA  . ASP A 1 344 ? 98.037  86.940  84.016  1.00 158.87 ? 344 ASP A CA  1 
ATOM   2565 C C   . ASP A 1 344 ? 99.208  86.152  83.449  1.00 158.87 ? 344 ASP A C   1 
ATOM   2566 O O   . ASP A 1 344 ? 99.677  85.220  84.109  1.00 158.87 ? 344 ASP A O   1 
ATOM   2567 C CB  . ASP A 1 344 ? 96.754  86.124  83.801  1.00 158.87 ? 344 ASP A CB  1 
ATOM   2568 C CG  . ASP A 1 344 ? 96.452  85.893  82.332  1.00 158.87 ? 344 ASP A CG  1 
ATOM   2569 O OD1 . ASP A 1 344 ? 96.217  86.882  81.605  1.00 158.87 ? 344 ASP A OD1 1 
ATOM   2570 O OD2 . ASP A 1 344 ? 96.455  84.719  81.904  1.00 158.87 ? 344 ASP A OD2 1 
ATOM   2571 N N   . ALA A 1 345 ? 99.687  86.498  82.252  1.00 156.67 ? 345 ALA A N   1 
ATOM   2572 C CA  . ALA A 1 345 ? 100.799 85.769  81.652  1.00 156.67 ? 345 ALA A CA  1 
ATOM   2573 C C   . ALA A 1 345 ? 102.078 85.933  82.462  1.00 156.67 ? 345 ALA A C   1 
ATOM   2574 O O   . ALA A 1 345 ? 102.865 84.982  82.589  1.00 156.67 ? 345 ALA A O   1 
ATOM   2575 C CB  . ALA A 1 345 ? 101.008 86.246  80.216  1.00 156.67 ? 345 ALA A CB  1 
ATOM   2576 N N   . VAL A 1 346 ? 102.292 87.126  83.017  1.00 160.26 ? 346 VAL A N   1 
ATOM   2577 C CA  . VAL A 1 346 ? 103.409 87.344  83.929  1.00 160.26 ? 346 VAL A CA  1 
ATOM   2578 C C   . VAL A 1 346 ? 103.286 86.428  85.138  1.00 160.26 ? 346 VAL A C   1 
ATOM   2579 O O   . VAL A 1 346 ? 104.277 85.858  85.607  1.00 160.26 ? 346 VAL A O   1 
ATOM   2580 C CB  . VAL A 1 346 ? 103.476 88.829  84.335  1.00 160.26 ? 346 VAL A CB  1 
ATOM   2581 C CG1 . VAL A 1 346 ? 104.333 89.021  85.577  1.00 160.26 ? 346 VAL A CG1 1 
ATOM   2582 C CG2 . VAL A 1 346 ? 104.006 89.669  83.180  1.00 160.26 ? 346 VAL A CG2 1 
ATOM   2583 N N   . SER A 1 347 ? 102.062 86.252  85.646  1.00 163.18 ? 347 SER A N   1 
ATOM   2584 C CA  . SER A 1 347 ? 101.848 85.331  86.758  1.00 163.18 ? 347 SER A CA  1 
ATOM   2585 C C   . SER A 1 347 ? 102.115 83.884  86.358  1.00 163.18 ? 347 SER A C   1 
ATOM   2586 O O   . SER A 1 347 ? 102.591 83.095  87.179  1.00 163.18 ? 347 SER A O   1 
ATOM   2587 C CB  . SER A 1 347 ? 100.426 85.476  87.299  1.00 163.18 ? 347 SER A CB  1 
ATOM   2588 O OG  . SER A 1 347 ? 100.307 84.882  88.580  1.00 163.18 ? 347 SER A OG  1 
ATOM   2589 N N   . GLU A 1 348 ? 101.821 83.513  85.108  1.00 166.65 ? 348 GLU A N   1 
ATOM   2590 C CA  . GLU A 1 348 ? 102.142 82.164  84.644  1.00 166.65 ? 348 GLU A CA  1 
ATOM   2591 C C   . GLU A 1 348 ? 103.647 81.931  84.645  1.00 166.65 ? 348 GLU A C   1 
ATOM   2592 O O   . GLU A 1 348 ? 104.137 80.917  85.170  1.00 166.65 ? 348 GLU A O   1 
ATOM   2593 C CB  . GLU A 1 348 ? 101.573 81.933  83.243  1.00 166.65 ? 348 GLU A CB  1 
ATOM   2594 C CG  . GLU A 1 348 ? 100.083 82.176  83.108  1.00 166.65 ? 348 GLU A CG  1 
ATOM   2595 C CD  . GLU A 1 348 ? 99.563  81.795  81.736  1.00 166.65 ? 348 GLU A CD  1 
ATOM   2596 O OE1 . GLU A 1 348 ? 100.015 80.765  81.195  1.00 166.65 ? 348 GLU A OE1 1 
ATOM   2597 O OE2 . GLU A 1 348 ? 98.697  82.519  81.202  1.00 166.65 ? 348 GLU A OE2 1 
ATOM   2598 N N   . VAL A 1 349 ? 104.399 82.877  84.071  1.00 167.80 ? 349 VAL A N   1 
ATOM   2599 C CA  . VAL A 1 349 ? 105.853 82.743  84.071  1.00 167.80 ? 349 VAL A CA  1 
ATOM   2600 C C   . VAL A 1 349 ? 106.391 82.769  85.496  1.00 167.80 ? 349 VAL A C   1 
ATOM   2601 O O   . VAL A 1 349 ? 107.353 82.062  85.812  1.00 167.80 ? 349 VAL A O   1 
ATOM   2602 C CB  . VAL A 1 349 ? 106.504 83.831  83.200  1.00 167.80 ? 349 VAL A CB  1 
ATOM   2603 C CG1 . VAL A 1 349 ? 107.975 83.515  82.968  1.00 167.80 ? 349 VAL A CG1 1 
ATOM   2604 C CG2 . VAL A 1 349 ? 105.789 83.936  81.870  1.00 167.80 ? 349 VAL A CG2 1 
ATOM   2605 N N   . GLN A 1 350 ? 105.766 83.551  86.380  1.00 171.83 ? 350 GLN A N   1 
ATOM   2606 C CA  . GLN A 1 350 ? 106.128 83.543  87.794  1.00 171.83 ? 350 GLN A CA  1 
ATOM   2607 C C   . GLN A 1 350 ? 105.943 82.162  88.404  1.00 171.83 ? 350 GLN A C   1 
ATOM   2608 O O   . GLN A 1 350 ? 106.825 81.659  89.109  1.00 171.83 ? 350 GLN A O   1 
ATOM   2609 C CB  . GLN A 1 350 ? 105.293 84.585  88.544  1.00 171.83 ? 350 GLN A CB  1 
ATOM   2610 C CG  . GLN A 1 350 ? 105.215 84.393  90.056  1.00 171.83 ? 350 GLN A CG  1 
ATOM   2611 C CD  . GLN A 1 350 ? 104.001 83.589  90.492  1.00 171.83 ? 350 GLN A CD  1 
ATOM   2612 O OE1 . GLN A 1 350 ? 102.867 83.915  90.139  1.00 171.83 ? 350 GLN A OE1 1 
ATOM   2613 N NE2 . GLN A 1 350 ? 104.236 82.529  91.257  1.00 171.83 ? 350 GLN A NE2 1 
ATOM   2614 N N   . SER A 1 351 ? 104.800 81.530  88.131  1.00 174.47 ? 351 SER A N   1 
ATOM   2615 C CA  . SER A 1 351 ? 104.545 80.193  88.652  1.00 174.47 ? 351 SER A CA  1 
ATOM   2616 C C   . SER A 1 351 ? 105.585 79.206  88.141  1.00 174.47 ? 351 SER A C   1 
ATOM   2617 O O   . SER A 1 351 ? 105.989 78.289  88.865  1.00 174.47 ? 351 SER A O   1 
ATOM   2618 C CB  . SER A 1 351 ? 103.134 79.740  88.275  1.00 174.47 ? 351 SER A CB  1 
ATOM   2619 O OG  . SER A 1 351 ? 102.995 79.599  86.873  1.00 174.47 ? 351 SER A OG  1 
ATOM   2620 N N   . GLN A 1 352 ? 106.039 79.383  86.901  1.00 173.59 ? 352 GLN A N   1 
ATOM   2621 C CA  . GLN A 1 352 ? 107.114 78.535  86.400  1.00 173.59 ? 352 GLN A CA  1 
ATOM   2622 C C   . GLN A 1 352 ? 108.511 79.025  86.776  1.00 173.59 ? 352 GLN A C   1 
ATOM   2623 O O   . GLN A 1 352 ? 109.486 78.340  86.448  1.00 173.59 ? 352 GLN A O   1 
ATOM   2624 C CB  . GLN A 1 352 ? 107.019 78.387  84.879  1.00 173.59 ? 352 GLN A CB  1 
ATOM   2625 C CG  . GLN A 1 352 ? 105.788 77.629  84.416  1.00 173.59 ? 352 GLN A CG  1 
ATOM   2626 C CD  . GLN A 1 352 ? 105.031 78.353  83.325  1.00 173.59 ? 352 GLN A CD  1 
ATOM   2627 O OE1 . GLN A 1 352 ? 105.463 79.401  82.845  1.00 173.59 ? 352 GLN A OE1 1 
ATOM   2628 N NE2 . GLN A 1 352 ? 103.889 77.803  82.932  1.00 173.59 ? 352 GLN A NE2 1 
ATOM   2629 N N   . LEU A 1 353 ? 108.648 80.172  87.443  1.00 176.95 ? 353 LEU A N   1 
ATOM   2630 C CA  . LEU A 1 353 ? 109.972 80.723  87.727  1.00 176.95 ? 353 LEU A CA  1 
ATOM   2631 C C   . LEU A 1 353 ? 110.298 80.847  89.209  1.00 176.95 ? 353 LEU A C   1 
ATOM   2632 O O   . LEU A 1 353 ? 111.454 80.651  89.588  1.00 176.95 ? 353 LEU A O   1 
ATOM   2633 C CB  . LEU A 1 353 ? 110.133 82.095  87.059  1.00 176.95 ? 353 LEU A CB  1 
ATOM   2634 C CG  . LEU A 1 353 ? 111.117 82.148  85.885  1.00 176.95 ? 353 LEU A CG  1 
ATOM   2635 C CD1 . LEU A 1 353 ? 111.517 83.578  85.545  1.00 176.95 ? 353 LEU A CD1 1 
ATOM   2636 C CD2 . LEU A 1 353 ? 112.350 81.300  86.173  1.00 176.95 ? 353 LEU A CD2 1 
ATOM   2637 N N   . GLY A 1 354 ? 109.336 81.177  90.064  1.00 173.36 ? 354 GLY A N   1 
ATOM   2638 C CA  . GLY A 1 354 ? 109.632 81.256  91.481  1.00 173.36 ? 354 GLY A CA  1 
ATOM   2639 C C   . GLY A 1 354 ? 108.475 81.822  92.277  1.00 173.36 ? 354 GLY A C   1 
ATOM   2640 O O   . GLY A 1 354 ? 107.415 82.157  91.741  1.00 173.36 ? 354 GLY A O   1 
ATOM   2641 N N   . ARG A 1 355 ? 108.709 81.922  93.584  1.00 166.23 ? 355 ARG A N   1 
ATOM   2642 C CA  . ARG A 1 355 ? 107.700 82.422  94.507  1.00 166.23 ? 355 ARG A CA  1 
ATOM   2643 C C   . ARG A 1 355 ? 107.495 83.922  94.307  1.00 166.23 ? 355 ARG A C   1 
ATOM   2644 O O   . ARG A 1 355 ? 108.395 84.641  93.869  1.00 166.23 ? 355 ARG A O   1 
ATOM   2645 C CB  . ARG A 1 355 ? 108.117 82.120  95.950  1.00 166.23 ? 355 ARG A CB  1 
ATOM   2646 C CG  . ARG A 1 355 ? 107.078 82.449  97.015  1.00 166.23 ? 355 ARG A CG  1 
ATOM   2647 C CD  . ARG A 1 355 ? 107.716 82.692  98.377  1.00 166.23 ? 355 ARG A CD  1 
ATOM   2648 N NE  . ARG A 1 355 ? 108.371 83.992  98.464  1.00 166.23 ? 355 ARG A NE  1 
ATOM   2649 C CZ  . ARG A 1 355 ? 109.638 84.172  98.814  1.00 166.23 ? 355 ARG A CZ  1 
ATOM   2650 N NH1 . ARG A 1 355 ? 110.423 83.152  99.118  1.00 166.23 ? 355 ARG A NH1 1 
ATOM   2651 N NH2 . ARG A 1 355 ? 110.127 85.408  98.865  1.00 166.23 ? 355 ARG A NH2 1 
ATOM   2652 N N   . LEU A 1 356 ? 106.288 84.390  94.615  1.00 167.85 ? 356 LEU A N   1 
ATOM   2653 C CA  . LEU A 1 356 ? 105.971 85.802  94.456  1.00 167.85 ? 356 LEU A CA  1 
ATOM   2654 C C   . LEU A 1 356 ? 106.761 86.654  95.447  1.00 167.85 ? 356 LEU A C   1 
ATOM   2655 O O   . LEU A 1 356 ? 107.005 86.258  96.589  1.00 167.85 ? 356 LEU A O   1 
ATOM   2656 C CB  . LEU A 1 356 ? 104.472 86.034  94.641  1.00 167.85 ? 356 LEU A CB  1 
ATOM   2657 C CG  . LEU A 1 356 ? 103.940 87.410  94.234  1.00 167.85 ? 356 LEU A CG  1 
ATOM   2658 C CD1 . LEU A 1 356 ? 103.500 87.408  92.778  1.00 167.85 ? 356 LEU A CD1 1 
ATOM   2659 C CD2 . LEU A 1 356 ? 102.800 87.838  95.145  1.00 167.85 ? 356 LEU A CD2 1 
ATOM   2660 N N   . ARG A 1 357 ? 107.162 87.839  94.991  1.00 159.28 ? 357 ARG A N   1 
ATOM   2661 C CA  . ARG A 1 357 ? 107.919 88.778  95.804  1.00 159.28 ? 357 ARG A CA  1 
ATOM   2662 C C   . ARG A 1 357 ? 106.953 89.714  96.535  1.00 159.28 ? 357 ARG A C   1 
ATOM   2663 O O   . ARG A 1 357 ? 105.735 89.517  96.526  1.00 159.28 ? 357 ARG A O   1 
ATOM   2664 C CB  . ARG A 1 357 ? 108.912 89.540  94.926  1.00 159.28 ? 357 ARG A CB  1 
ATOM   2665 C CG  . ARG A 1 357 ? 110.182 89.994  95.635  1.00 159.28 ? 357 ARG A CG  1 
ATOM   2666 C CD  . ARG A 1 357 ? 110.502 91.438  95.285  1.00 159.28 ? 357 ARG A CD  1 
ATOM   2667 N NE  . ARG A 1 357 ? 111.743 91.895  95.897  1.00 159.28 ? 357 ARG A NE  1 
ATOM   2668 C CZ  . ARG A 1 357 ? 111.822 92.887  96.773  1.00 159.28 ? 357 ARG A CZ  1 
ATOM   2669 N NH1 . ARG A 1 357 ? 110.745 93.547  97.169  1.00 159.28 ? 357 ARG A NH1 1 
ATOM   2670 N NH2 . ARG A 1 357 ? 113.010 93.225  97.266  1.00 159.28 ? 357 ARG A NH2 1 
ATOM   2671 N N   . ALA A 1 358 ? 107.491 90.749  97.177  1.00 148.63 ? 358 ALA A N   1 
ATOM   2672 C CA  . ALA A 1 358 ? 106.702 91.715  97.923  1.00 148.63 ? 358 ALA A CA  1 
ATOM   2673 C C   . ALA A 1 358 ? 107.061 93.124  97.474  1.00 148.63 ? 358 ALA A C   1 
ATOM   2674 O O   . ALA A 1 358 ? 108.139 93.370  96.927  1.00 148.63 ? 358 ALA A O   1 
ATOM   2675 C CB  . ALA A 1 358 ? 106.916 91.571  99.436  1.00 148.63 ? 358 ALA A CB  1 
ATOM   2676 N N   . ALA A 1 359 ? 106.138 94.050  97.715  1.00 135.03 ? 359 ALA A N   1 
ATOM   2677 C CA  . ALA A 1 359 ? 106.294 95.423  97.264  1.00 135.03 ? 359 ALA A CA  1 
ATOM   2678 C C   . ALA A 1 359 ? 107.244 96.198  98.174  1.00 135.03 ? 359 ALA A C   1 
ATOM   2679 O O   . ALA A 1 359 ? 107.546 95.792  99.299  1.00 135.03 ? 359 ALA A O   1 
ATOM   2680 C CB  . ALA A 1 359 ? 104.938 96.124  97.202  1.00 135.03 ? 359 ALA A CB  1 
ATOM   2681 N N   . GLU A 1 360 ? 107.718 97.334  97.660  1.00 118.26 ? 360 GLU A N   1 
ATOM   2682 C CA  . GLU A 1 360 ? 108.667 98.167  98.391  1.00 118.26 ? 360 GLU A CA  1 
ATOM   2683 C C   . GLU A 1 360 ? 107.989 98.980  99.491  1.00 118.26 ? 360 GLU A C   1 
ATOM   2684 O O   . GLU A 1 360 ? 108.556 99.152  100.576 1.00 118.26 ? 360 GLU A O   1 
ATOM   2685 C CB  . GLU A 1 360 ? 109.397 99.087  97.407  1.00 118.26 ? 360 GLU A CB  1 
ATOM   2686 C CG  . GLU A 1 360 ? 109.826 100.435 97.968  1.00 118.26 ? 360 GLU A CG  1 
ATOM   2687 C CD  . GLU A 1 360 ? 111.102 100.351 98.779  1.00 118.26 ? 360 GLU A CD  1 
ATOM   2688 O OE1 . GLU A 1 360 ? 112.143 99.953  98.214  1.00 118.26 ? 360 GLU A OE1 1 
ATOM   2689 O OE2 . GLU A 1 360 ? 111.067 100.683 99.982  1.00 118.26 ? 360 GLU A OE2 1 
ATOM   2690 N N   . ASN A 1 361 ? 106.773 99.470  99.234  1.00 119.71 ? 361 ASN A N   1 
ATOM   2691 C CA  . ASN A 1 361 ? 106.143 100.435 100.134 1.00 119.71 ? 361 ASN A CA  1 
ATOM   2692 C C   . ASN A 1 361 ? 105.794 99.820  101.487 1.00 119.71 ? 361 ASN A C   1 
ATOM   2693 O O   . ASN A 1 361 ? 105.902 100.490 102.520 1.00 119.71 ? 361 ASN A O   1 
ATOM   2694 C CB  . ASN A 1 361 ? 104.898 101.028 99.475  1.00 119.71 ? 361 ASN A CB  1 
ATOM   2695 C CG  . ASN A 1 361 ? 103.982 99.968  98.896  1.00 119.71 ? 361 ASN A CG  1 
ATOM   2696 O OD1 . ASN A 1 361 ? 104.247 98.772  99.011  1.00 119.71 ? 361 ASN A OD1 1 
ATOM   2697 N ND2 . ASN A 1 361 ? 102.895 100.403 98.269  1.00 119.71 ? 361 ASN A ND2 1 
ATOM   2698 N N   . ILE A 1 362 ? 105.355 98.559  101.502 1.00 108.90 ? 362 ILE A N   1 
ATOM   2699 C CA  . ILE A 1 362 ? 104.919 97.931  102.746 1.00 108.90 ? 362 ILE A CA  1 
ATOM   2700 C C   . ILE A 1 362 ? 106.104 97.748  103.686 1.00 108.90 ? 362 ILE A C   1 
ATOM   2701 O O   . ILE A 1 362 ? 107.236 97.495  103.252 1.00 108.90 ? 362 ILE A O   1 
ATOM   2702 C CB  . ILE A 1 362 ? 104.218 96.593  102.458 1.00 108.90 ? 362 ILE A CB  1 
ATOM   2703 C CG1 . ILE A 1 362 ? 105.012 95.780  101.434 1.00 108.90 ? 362 ILE A CG1 1 
ATOM   2704 C CG2 . ILE A 1 362 ? 102.794 96.830  101.976 1.00 108.90 ? 362 ILE A CG2 1 
ATOM   2705 C CD1 . ILE A 1 362 ? 104.338 94.488  101.024 1.00 108.90 ? 362 ILE A CD1 1 
ATOM   2706 N N   . ILE A 1 363 ? 105.846 97.882  104.987 1.00 79.73  ? 363 ILE A N   1 
ATOM   2707 C CA  . ILE A 1 363 ? 106.873 97.866  106.023 1.00 79.73  ? 363 ILE A CA  1 
ATOM   2708 C C   . ILE A 1 363 ? 106.580 96.724  106.986 1.00 79.73  ? 363 ILE A C   1 
ATOM   2709 O O   . ILE A 1 363 ? 105.422 96.510  107.365 1.00 79.73  ? 363 ILE A O   1 
ATOM   2710 C CB  . ILE A 1 363 ? 106.935 99.205  106.783 1.00 79.73  ? 363 ILE A CB  1 
ATOM   2711 C CG1 . ILE A 1 363 ? 106.615 100.374 105.849 1.00 79.73  ? 363 ILE A CG1 1 
ATOM   2712 C CG2 . ILE A 1 363 ? 108.296 99.386  107.434 1.00 79.73  ? 363 ILE A CG2 1 
ATOM   2713 C CD1 . ILE A 1 363 ? 106.251 101.652 106.577 1.00 79.73  ? 363 ILE A CD1 1 
ATOM   2714 N N   . ASN A 1 364 ? 107.623 95.991  107.379 1.00 64.30  ? 364 ASN A N   1 
ATOM   2715 C CA  . ASN A 1 364 ? 107.482 94.899  108.346 1.00 64.30  ? 364 ASN A CA  1 
ATOM   2716 C C   . ASN A 1 364 ? 107.702 95.440  109.755 1.00 64.30  ? 364 ASN A C   1 
ATOM   2717 O O   . ASN A 1 364 ? 108.827 95.494  110.273 1.00 64.30  ? 364 ASN A O   1 
ATOM   2718 C CB  . ASN A 1 364 ? 108.431 93.756  108.017 1.00 64.30  ? 364 ASN A CB  1 
ATOM   2719 C CG  . ASN A 1 364 ? 107.751 92.651  107.231 1.00 64.30  ? 364 ASN A CG  1 
ATOM   2720 O OD1 . ASN A 1 364 ? 106.543 92.696  106.998 1.00 64.30  ? 364 ASN A OD1 1 
ATOM   2721 N ND2 . ASN A 1 364 ? 108.521 91.650  106.826 1.00 64.30  ? 364 ASN A ND2 1 
ATOM   2722 N N   . TYR A 1 365 ? 106.593 95.828  110.390 1.00 54.02  ? 365 TYR A N   1 
ATOM   2723 C CA  . TYR A 1 365 ? 106.647 96.358  111.745 1.00 54.02  ? 365 TYR A CA  1 
ATOM   2724 C C   . TYR A 1 365 ? 107.131 95.306  112.732 1.00 54.02  ? 365 TYR A C   1 
ATOM   2725 O O   . TYR A 1 365 ? 107.750 95.644  113.748 1.00 54.02  ? 365 TYR A O   1 
ATOM   2726 C CB  . TYR A 1 365 ? 105.269 96.878  112.147 1.00 54.02  ? 365 TYR A CB  1 
ATOM   2727 C CG  . TYR A 1 365 ? 104.816 98.057  111.319 1.00 54.02  ? 365 TYR A CG  1 
ATOM   2728 C CD1 . TYR A 1 365 ? 105.529 99.245  111.320 1.00 54.02  ? 365 TYR A CD1 1 
ATOM   2729 C CD2 . TYR A 1 365 ? 103.679 97.976  110.527 1.00 54.02  ? 365 TYR A CD2 1 
ATOM   2730 C CE1 . TYR A 1 365 ? 105.122 100.323 110.562 1.00 54.02  ? 365 TYR A CE1 1 
ATOM   2731 C CE2 . TYR A 1 365 ? 103.263 99.049  109.765 1.00 54.02  ? 365 TYR A CE2 1 
ATOM   2732 C CZ  . TYR A 1 365 ? 103.988 100.219 109.786 1.00 54.02  ? 365 TYR A CZ  1 
ATOM   2733 O OH  . TYR A 1 365 ? 103.582 101.293 109.030 1.00 54.02  ? 365 TYR A OH  1 
ATOM   2734 N N   . SER A 1 366 ? 106.858 94.029  112.450 1.00 49.68  ? 366 SER A N   1 
ATOM   2735 C CA  . SER A 1 366 ? 107.388 92.959  113.287 1.00 49.68  ? 366 SER A CA  1 
ATOM   2736 C C   . SER A 1 366 ? 108.909 92.942  113.253 1.00 49.68  ? 366 SER A C   1 
ATOM   2737 O O   . SER A 1 366 ? 109.557 92.800  114.297 1.00 49.68  ? 366 SER A O   1 
ATOM   2738 C CB  . SER A 1 366 ? 106.827 91.613  112.836 1.00 49.68  ? 366 SER A CB  1 
ATOM   2739 O OG  . SER A 1 366 ? 107.119 91.378  111.470 1.00 49.68  ? 366 SER A OG  1 
ATOM   2740 N N   . TRP A 1 367 ? 109.499 93.098  112.064 1.00 51.61  ? 367 TRP A N   1 
ATOM   2741 C CA  . TRP A 1 367 ? 110.953 93.183  111.969 1.00 51.61  ? 367 TRP A CA  1 
ATOM   2742 C C   . TRP A 1 367 ? 111.488 94.417  112.681 1.00 51.61  ? 367 TRP A C   1 
ATOM   2743 O O   . TRP A 1 367 ? 112.533 94.352  113.338 1.00 51.61  ? 367 TRP A O   1 
ATOM   2744 C CB  . TRP A 1 367 ? 111.398 93.170  110.506 1.00 51.61  ? 367 TRP A CB  1 
ATOM   2745 C CG  . TRP A 1 367 ? 112.437 92.127  110.217 1.00 51.61  ? 367 TRP A CG  1 
ATOM   2746 C CD1 . TRP A 1 367 ? 113.720 92.349  109.810 1.00 51.61  ? 367 TRP A CD1 1 
ATOM   2747 C CD2 . TRP A 1 367 ? 112.296 90.706  110.337 1.00 51.61  ? 367 TRP A CD2 1 
ATOM   2748 N NE1 . TRP A 1 367 ? 114.383 91.158  109.659 1.00 51.61  ? 367 TRP A NE1 1 
ATOM   2749 C CE2 . TRP A 1 367 ? 113.532 90.133  109.976 1.00 51.61  ? 367 TRP A CE2 1 
ATOM   2750 C CE3 . TRP A 1 367 ? 111.245 89.862  110.707 1.00 51.61  ? 367 TRP A CE3 1 
ATOM   2751 C CZ2 . TRP A 1 367 ? 113.745 88.757  109.975 1.00 51.61  ? 367 TRP A CZ2 1 
ATOM   2752 C CZ3 . TRP A 1 367 ? 111.459 88.496  110.706 1.00 51.61  ? 367 TRP A CZ3 1 
ATOM   2753 C CH2 . TRP A 1 367 ? 112.699 87.957  110.342 1.00 51.61  ? 367 TRP A CH2 1 
ATOM   2754 N N   . PHE A 1 368 ? 110.785 95.548  112.569 1.00 35.92  ? 368 PHE A N   1 
ATOM   2755 C CA  . PHE A 1 368 ? 111.212 96.751  113.284 1.00 35.92  ? 368 PHE A CA  1 
ATOM   2756 C C   . PHE A 1 368 ? 111.254 96.518  114.795 1.00 35.92  ? 368 PHE A C   1 
ATOM   2757 O O   . PHE A 1 368 ? 112.264 96.802  115.461 1.00 35.92  ? 368 PHE A O   1 
ATOM   2758 C CB  . PHE A 1 368 ? 110.276 97.907  112.943 1.00 35.92  ? 368 PHE A CB  1 
ATOM   2759 C CG  . PHE A 1 368 ? 110.862 99.257  113.203 1.00 35.92  ? 368 PHE A CG  1 
ATOM   2760 C CD1 . PHE A 1 368 ? 111.994 99.674  112.529 1.00 35.92  ? 368 PHE A CD1 1 
ATOM   2761 C CD2 . PHE A 1 368 ? 110.282 100.108 114.124 1.00 35.92  ? 368 PHE A CD2 1 
ATOM   2762 C CE1 . PHE A 1 368 ? 112.536 100.918 112.770 1.00 35.92  ? 368 PHE A CE1 1 
ATOM   2763 C CE2 . PHE A 1 368 ? 110.821 101.352 114.369 1.00 35.92  ? 368 PHE A CE2 1 
ATOM   2764 C CZ  . PHE A 1 368 ? 111.950 101.756 113.692 1.00 35.92  ? 368 PHE A CZ  1 
ATOM   2765 N N   . ALA A 1 369 ? 110.162 95.986  115.349 1.00 34.95  ? 369 ALA A N   1 
ATOM   2766 C CA  . ALA A 1 369 ? 110.093 95.757  116.788 1.00 34.95  ? 369 ALA A CA  1 
ATOM   2767 C C   . ALA A 1 369 ? 111.110 94.715  117.238 1.00 34.95  ? 369 ALA A C   1 
ATOM   2768 O O   . ALA A 1 369 ? 111.724 94.857  118.304 1.00 34.95  ? 369 ALA A O   1 
ATOM   2769 C CB  . ALA A 1 369 ? 108.680 95.336  117.185 1.00 34.95  ? 369 ALA A CB  1 
ATOM   2770 N N   . LEU A 1 370 ? 111.298 93.656  116.446 1.00 33.85  ? 370 LEU A N   1 
ATOM   2771 C CA  . LEU A 1 370 ? 112.282 92.639  116.798 1.00 33.85  ? 370 LEU A CA  1 
ATOM   2772 C C   . LEU A 1 370 ? 113.690 93.214  116.786 1.00 33.85  ? 370 LEU A C   1 
ATOM   2773 O O   . LEU A 1 370 ? 114.518 92.858  117.632 1.00 33.85  ? 370 LEU A O   1 
ATOM   2774 C CB  . LEU A 1 370 ? 112.174 91.449  115.847 1.00 33.85  ? 370 LEU A CB  1 
ATOM   2775 C CG  . LEU A 1 370 ? 112.772 90.145  116.375 1.00 33.85  ? 370 LEU A CG  1 
ATOM   2776 C CD1 . LEU A 1 370 ? 111.986 89.651  117.576 1.00 33.85  ? 370 LEU A CD1 1 
ATOM   2777 C CD2 . LEU A 1 370 ? 112.803 89.089  115.285 1.00 33.85  ? 370 LEU A CD2 1 
ATOM   2778 N N   . GLY A 1 371 ? 113.980 94.110  115.840 1.00 33.93  ? 371 GLY A N   1 
ATOM   2779 C CA  . GLY A 1 371 ? 115.277 94.763  115.830 1.00 33.93  ? 371 GLY A CA  1 
ATOM   2780 C C   . GLY A 1 371 ? 115.509 95.612  117.065 1.00 33.93  ? 371 GLY A C   1 
ATOM   2781 O O   . GLY A 1 371 ? 116.592 95.579  117.656 1.00 33.93  ? 371 GLY A O   1 
ATOM   2782 N N   . ILE A 1 372 ? 114.491 96.372  117.482 1.00 32.47  ? 372 ILE A N   1 
ATOM   2783 C CA  . ILE A 1 372 ? 114.633 97.174  118.701 1.00 32.47  ? 372 ILE A CA  1 
ATOM   2784 C C   . ILE A 1 372 ? 114.851 96.278  119.920 1.00 32.47  ? 372 ILE A C   1 
ATOM   2785 O O   . ILE A 1 372 ? 115.711 96.554  120.773 1.00 32.47  ? 372 ILE A O   1 
ATOM   2786 C CB  . ILE A 1 372 ? 113.415 98.098  118.887 1.00 32.47  ? 372 ILE A CB  1 
ATOM   2787 C CG1 . ILE A 1 372 ? 113.212 98.972  117.651 1.00 32.47  ? 372 ILE A CG1 1 
ATOM   2788 C CG2 . ILE A 1 372 ? 113.590 98.967  120.119 1.00 32.47  ? 372 ILE A CG2 1 
ATOM   2789 C CD1 . ILE A 1 372 ? 114.329 99.958  117.418 1.00 32.47  ? 372 ILE A CD1 1 
ATOM   2790 N N   . ALA A 1 373 ? 114.077 95.193  120.021 1.00 33.30  ? 373 ALA A N   1 
ATOM   2791 C CA  . ALA A 1 373 ? 114.208 94.289  121.162 1.00 33.30  ? 373 ALA A CA  1 
ATOM   2792 C C   . ALA A 1 373 ? 115.581 93.627  121.198 1.00 33.30  ? 373 ALA A C   1 
ATOM   2793 O O   . ALA A 1 373 ? 116.195 93.510  122.267 1.00 33.30  ? 373 ALA A O   1 
ATOM   2794 C CB  . ALA A 1 373 ? 113.106 93.232  121.122 1.00 33.30  ? 373 ALA A CB  1 
ATOM   2795 N N   . LEU A 1 374 ? 116.080 93.187  120.041 1.00 36.03  ? 374 LEU A N   1 
ATOM   2796 C CA  . LEU A 1 374 ? 117.407 92.586  119.993 1.00 36.03  ? 374 LEU A CA  1 
ATOM   2797 C C   . LEU A 1 374 ? 118.488 93.609  120.310 1.00 36.03  ? 374 LEU A C   1 
ATOM   2798 O O   . LEU A 1 374 ? 119.513 93.264  120.905 1.00 36.03  ? 374 LEU A O   1 
ATOM   2799 C CB  . LEU A 1 374 ? 117.653 91.950  118.626 1.00 36.03  ? 374 LEU A CB  1 
ATOM   2800 C CG  . LEU A 1 374 ? 116.919 90.639  118.349 1.00 36.03  ? 374 LEU A CG  1 
ATOM   2801 C CD1 . LEU A 1 374 ? 117.500 89.957  117.122 1.00 36.03  ? 374 LEU A CD1 1 
ATOM   2802 C CD2 . LEU A 1 374 ? 116.983 89.720  119.559 1.00 36.03  ? 374 LEU A CD2 1 
ATOM   2803 N N   . SER A 1 375 ? 118.281 94.870  119.921 1.00 35.25  ? 375 SER A N   1 
ATOM   2804 C CA  . SER A 1 375 ? 119.233 95.914  120.288 1.00 35.25  ? 375 SER A CA  1 
ATOM   2805 C C   . SER A 1 375 ? 119.309 96.080  121.800 1.00 35.25  ? 375 SER A C   1 
ATOM   2806 O O   . SER A 1 375 ? 120.405 96.171  122.368 1.00 35.25  ? 375 SER A O   1 
ATOM   2807 C CB  . SER A 1 375 ? 118.846 97.234  119.625 1.00 35.25  ? 375 SER A CB  1 
ATOM   2808 O OG  . SER A 1 375 ? 117.961 97.972  120.449 1.00 35.25  ? 375 SER A OG  1 
ATOM   2809 N N   . ALA A 1 376 ? 118.154 96.108  122.469 1.00 37.02  ? 376 ALA A N   1 
ATOM   2810 C CA  . ALA A 1 376 ? 118.160 96.210  123.929 1.00 37.02  ? 376 ALA A CA  1 
ATOM   2811 C C   . ALA A 1 376 ? 118.819 94.990  124.571 1.00 37.02  ? 376 ALA A C   1 
ATOM   2812 O O   . ALA A 1 376 ? 119.623 95.122  125.509 1.00 37.02  ? 376 ALA A O   1 
ATOM   2813 C CB  . ALA A 1 376 ? 116.735 96.388  124.450 1.00 37.02  ? 376 ALA A CB  1 
ATOM   2814 N N   . ALA A 1 377 ? 118.500 93.793  124.070 1.00 41.13  ? 377 ALA A N   1 
ATOM   2815 C CA  . ALA A 1 377 ? 119.083 92.577  124.629 1.00 41.13  ? 377 ALA A CA  1 
ATOM   2816 C C   . ALA A 1 377 ? 120.597 92.554  124.454 1.00 41.13  ? 377 ALA A C   1 
ATOM   2817 O O   . ALA A 1 377 ? 121.329 92.152  125.366 1.00 41.13  ? 377 ALA A O   1 
ATOM   2818 C CB  . ALA A 1 377 ? 118.451 91.345  123.984 1.00 41.13  ? 377 ALA A CB  1 
ATOM   2819 N N   . LEU A 1 378 ? 121.086 92.978  123.286 1.00 44.00  ? 378 LEU A N   1 
ATOM   2820 C CA  . LEU A 1 378 ? 122.526 93.049  123.062 1.00 44.00  ? 378 LEU A CA  1 
ATOM   2821 C C   . LEU A 1 378 ? 123.175 94.095  123.956 1.00 44.00  ? 378 LEU A C   1 
ATOM   2822 O O   . LEU A 1 378 ? 124.286 93.887  124.456 1.00 44.00  ? 378 LEU A O   1 
ATOM   2823 C CB  . LEU A 1 378 ? 122.815 93.347  121.593 1.00 44.00  ? 378 LEU A CB  1 
ATOM   2824 C CG  . LEU A 1 378 ? 124.154 92.836  121.059 1.00 44.00  ? 378 LEU A CG  1 
ATOM   2825 C CD1 . LEU A 1 378 ? 124.454 91.441  121.587 1.00 44.00  ? 378 LEU A CD1 1 
ATOM   2826 C CD2 . LEU A 1 378 ? 124.161 92.850  119.540 1.00 44.00  ? 378 LEU A CD2 1 
ATOM   2827 N N   . GLY A 1 379 ? 122.504 95.230  124.166 1.00 47.12  ? 379 GLY A N   1 
ATOM   2828 C CA  . GLY A 1 379 ? 123.035 96.232  125.071 1.00 47.12  ? 379 GLY A CA  1 
ATOM   2829 C C   . GLY A 1 379 ? 123.096 95.779  126.513 1.00 47.12  ? 379 GLY A C   1 
ATOM   2830 O O   . GLY A 1 379 ? 123.879 96.330  127.293 1.00 47.12  ? 379 GLY A O   1 
ATOM   2831 N N   . ILE A 1 380 ? 122.276 94.793  126.885 1.00 52.19  ? 380 ILE A N   1 
ATOM   2832 C CA  . ILE A 1 380 ? 122.304 94.286  128.258 1.00 52.19  ? 380 ILE A CA  1 
ATOM   2833 C C   . ILE A 1 380 ? 123.656 93.662  128.597 1.00 52.19  ? 380 ILE A C   1 
ATOM   2834 O O   . ILE A 1 380 ? 124.187 93.872  129.696 1.00 52.19  ? 380 ILE A O   1 
ATOM   2835 C CB  . ILE A 1 380 ? 121.148 93.297  128.489 1.00 52.19  ? 380 ILE A CB  1 
ATOM   2836 C CG1 . ILE A 1 380 ? 119.838 94.070  128.586 1.00 52.19  ? 380 ILE A CG1 1 
ATOM   2837 C CG2 . ILE A 1 380 ? 121.379 92.455  129.738 1.00 52.19  ? 380 ILE A CG2 1 
ATOM   2838 C CD1 . ILE A 1 380 ? 119.698 94.793  129.903 1.00 52.19  ? 380 ILE A CD1 1 
ATOM   2839 N N   . VAL A 1 381 ? 124.232 92.888  127.670 1.00 59.45  ? 381 VAL A N   1 
ATOM   2840 C CA  . VAL A 1 381 ? 125.437 92.121  127.978 1.00 59.45  ? 381 VAL A CA  1 
ATOM   2841 C C   . VAL A 1 381 ? 126.587 93.052  128.369 1.00 59.45  ? 381 VAL A C   1 
ATOM   2842 O O   . VAL A 1 381 ? 126.673 94.203  127.921 1.00 59.45  ? 381 VAL A O   1 
ATOM   2843 C CB  . VAL A 1 381 ? 125.832 91.214  126.797 1.00 59.45  ? 381 VAL A CB  1 
ATOM   2844 C CG1 . VAL A 1 381 ? 126.570 91.994  125.714 1.00 59.45  ? 381 VAL A CG1 1 
ATOM   2845 C CG2 . VAL A 1 381 ? 126.666 90.032  127.277 1.00 59.45  ? 381 VAL A CG2 1 
ATOM   2846 N N   . GLY A 1 382 ? 127.454 92.559  129.250 1.00 76.05  ? 382 GLY A N   1 
ATOM   2847 C CA  . GLY A 1 382 ? 128.560 93.357  129.742 1.00 76.05  ? 382 GLY A CA  1 
ATOM   2848 C C   . GLY A 1 382 ? 129.636 92.489  130.348 1.00 76.05  ? 382 GLY A C   1 
ATOM   2849 O O   . GLY A 1 382 ? 129.375 91.370  130.802 1.00 76.05  ? 382 GLY A O   1 
ATOM   2850 N N   . THR A 1 383 ? 130.859 93.015  130.357 1.00 89.51  ? 383 THR A N   1 
ATOM   2851 C CA  . THR A 1 383 ? 132.011 92.323  130.916 1.00 89.51  ? 383 THR A CA  1 
ATOM   2852 C C   . THR A 1 383 ? 132.670 93.219  131.953 1.00 89.51  ? 383 THR A C   1 
ATOM   2853 O O   . THR A 1 383 ? 132.390 94.416  132.031 1.00 89.51  ? 383 THR A O   1 
ATOM   2854 C CB  . THR A 1 383 ? 133.040 91.935  129.839 1.00 89.51  ? 383 THR A CB  1 
ATOM   2855 O OG1 . THR A 1 383 ? 133.965 93.014  129.648 1.00 89.51  ? 383 THR A OG1 1 
ATOM   2856 C CG2 . THR A 1 383 ? 132.357 91.617  128.515 1.00 89.51  ? 383 THR A CG2 1 
ATOM   2857 N N   . LYS A 1 384 ? 133.530 92.623  132.773 1.00 105.53 ? 384 LYS A N   1 
ATOM   2858 C CA  . LYS A 1 384 ? 134.289 93.359  133.773 1.00 105.53 ? 384 LYS A CA  1 
ATOM   2859 C C   . LYS A 1 384 ? 135.773 93.317  133.436 1.00 105.53 ? 384 LYS A C   1 
ATOM   2860 O O   . LYS A 1 384 ? 136.300 92.275  133.030 1.00 105.53 ? 384 LYS A O   1 
ATOM   2861 C CB  . LYS A 1 384 ? 134.049 92.801  135.182 1.00 105.53 ? 384 LYS A CB  1 
ATOM   2862 C CG  . LYS A 1 384 ? 134.367 91.323  135.354 1.00 105.53 ? 384 LYS A CG  1 
ATOM   2863 C CD  . LYS A 1 384 ? 134.180 90.885  136.799 1.00 105.53 ? 384 LYS A CD  1 
ATOM   2864 C CE  . LYS A 1 384 ? 132.769 91.163  137.289 1.00 105.53 ? 384 LYS A CE  1 
ATOM   2865 N NZ  . LYS A 1 384 ? 131.758 90.346  136.564 1.00 105.53 ? 384 LYS A NZ  1 
ATOM   2866 N N   . VAL A 1 385 ? 136.437 94.460  133.583 1.00 112.64 ? 385 VAL A N   1 
ATOM   2867 C CA  . VAL A 1 385 ? 137.874 94.581  133.355 1.00 112.64 ? 385 VAL A CA  1 
ATOM   2868 C C   . VAL A 1 385 ? 138.480 95.260  134.583 1.00 112.64 ? 385 VAL A C   1 
ATOM   2869 O O   . VAL A 1 385 ? 138.396 96.483  134.739 1.00 112.64 ? 385 VAL A O   1 
ATOM   2870 C CB  . VAL A 1 385 ? 138.203 95.330  132.052 1.00 112.64 ? 385 VAL A CB  1 
ATOM   2871 C CG1 . VAL A 1 385 ? 137.379 96.617  131.900 1.00 112.64 ? 385 VAL A CG1 1 
ATOM   2872 C CG2 . VAL A 1 385 ? 139.699 95.620  131.957 1.00 112.64 ? 385 VAL A CG2 1 
ATOM   2873 N N   . SER A 1 386 ? 139.077 94.458  135.468 1.00 121.71 ? 386 SER A N   1 
ATOM   2874 C CA  . SER A 1 386 ? 139.695 94.940  136.706 1.00 121.71 ? 386 SER A CA  1 
ATOM   2875 C C   . SER A 1 386 ? 138.711 95.757  137.544 1.00 121.71 ? 386 SER A C   1 
ATOM   2876 O O   . SER A 1 386 ? 139.030 96.833  138.054 1.00 121.71 ? 386 SER A O   1 
ATOM   2877 C CB  . SER A 1 386 ? 140.965 95.742  136.410 1.00 121.71 ? 386 SER A CB  1 
ATOM   2878 O OG  . SER A 1 386 ? 141.842 95.013  135.570 1.00 121.71 ? 386 SER A OG  1 
ATOM   2879 N N   . GLY A 1 387 ? 137.496 95.232  137.682 1.00 117.62 ? 387 GLY A N   1 
ATOM   2880 C CA  . GLY A 1 387 ? 136.478 95.881  138.481 1.00 117.62 ? 387 GLY A CA  1 
ATOM   2881 C C   . GLY A 1 387 ? 135.673 96.949  137.777 1.00 117.62 ? 387 GLY A C   1 
ATOM   2882 O O   . GLY A 1 387 ? 134.919 97.669  138.441 1.00 117.62 ? 387 GLY A O   1 
ATOM   2883 N N   . VAL A 1 388 ? 135.804 97.081  136.461 1.00 102.62 ? 388 VAL A N   1 
ATOM   2884 C CA  . VAL A 1 388 ? 135.054 98.062  135.686 1.00 102.62 ? 388 VAL A CA  1 
ATOM   2885 C C   . VAL A 1 388 ? 133.964 97.314  134.921 1.00 102.62 ? 388 VAL A C   1 
ATOM   2886 O O   . VAL A 1 388 ? 134.262 96.634  133.928 1.00 102.62 ? 388 VAL A O   1 
ATOM   2887 C CB  . VAL A 1 388 ? 135.961 98.846  134.729 1.00 102.62 ? 388 VAL A CB  1 
ATOM   2888 C CG1 . VAL A 1 388 ? 135.208 100.026 134.138 1.00 102.62 ? 388 VAL A CG1 1 
ATOM   2889 C CG2 . VAL A 1 388 ? 137.210 99.311  135.447 1.00 102.62 ? 388 VAL A CG2 1 
ATOM   2890 N N   . PRO A 1 389 ? 132.700 97.411  135.330 1.00 91.73  ? 389 PRO A N   1 
ATOM   2891 C CA  . PRO A 1 389 ? 131.613 96.720  134.601 1.00 91.73  ? 389 PRO A CA  1 
ATOM   2892 C C   . PRO A 1 389 ? 131.248 97.437  133.307 1.00 91.73  ? 389 PRO A C   1 
ATOM   2893 O O   . PRO A 1 389 ? 130.238 98.140  133.193 1.00 91.73  ? 389 PRO A O   1 
ATOM   2894 C CB  . PRO A 1 389 ? 130.469 96.724  135.626 1.00 91.73  ? 389 PRO A CB  1 
ATOM   2895 C CG  . PRO A 1 389 ? 131.061 97.214  136.928 1.00 91.73  ? 389 PRO A CG  1 
ATOM   2896 C CD  . PRO A 1 389 ? 132.211 98.071  136.547 1.00 91.73  ? 389 PRO A CD  1 
ATOM   2897 N N   . ILE A 1 390 ? 132.094 97.261  132.291 1.00 82.21  ? 390 ILE A N   1 
ATOM   2898 C CA  . ILE A 1 390 ? 131.831 97.876  130.999 1.00 82.21  ? 390 ILE A CA  1 
ATOM   2899 C C   . ILE A 1 390 ? 130.703 97.131  130.295 1.00 82.21  ? 390 ILE A C   1 
ATOM   2900 O O   . ILE A 1 390 ? 130.510 95.919  130.474 1.00 82.21  ? 390 ILE A O   1 
ATOM   2901 C CB  . ILE A 1 390 ? 133.105 97.912  130.134 1.00 82.21  ? 390 ILE A CB  1 
ATOM   2902 C CG1 . ILE A 1 390 ? 133.532 96.499  129.730 1.00 82.21  ? 390 ILE A CG1 1 
ATOM   2903 C CG2 . ILE A 1 390 ? 134.229 98.619  130.873 1.00 82.21  ? 390 ILE A CG2 1 
ATOM   2904 C CD1 . ILE A 1 390 ? 134.728 96.463  128.804 1.00 82.21  ? 390 ILE A CD1 1 
ATOM   2905 N N   . ALA A 1 391 ? 129.936 97.870  129.498 1.00 60.33  ? 391 ALA A N   1 
ATOM   2906 C CA  . ALA A 1 391 ? 128.823 97.313  128.748 1.00 60.33  ? 391 ALA A CA  1 
ATOM   2907 C C   . ALA A 1 391 ? 128.765 97.979  127.383 1.00 60.33  ? 391 ALA A C   1 
ATOM   2908 O O   . ALA A 1 391 ? 129.271 99.087  127.189 1.00 60.33  ? 391 ALA A O   1 
ATOM   2909 C CB  . ALA A 1 391 ? 127.492 97.495  129.487 1.00 60.33  ? 391 ALA A CB  1 
ATOM   2910 N N   . LEU A 1 392 ? 128.146 97.281  126.429 1.00 44.53  ? 392 LEU A N   1 
ATOM   2911 C CA  . LEU A 1 392 ? 128.016 97.829  125.083 1.00 44.53  ? 392 LEU A CA  1 
ATOM   2912 C C   . LEU A 1 392 ? 127.134 99.071  125.075 1.00 44.53  ? 392 LEU A C   1 
ATOM   2913 O O   . LEU A 1 392 ? 127.421 100.040 124.364 1.00 44.53  ? 392 LEU A O   1 
ATOM   2914 C CB  . LEU A 1 392 ? 127.463 96.768  124.135 1.00 44.53  ? 392 LEU A CB  1 
ATOM   2915 C CG  . LEU A 1 392 ? 127.740 96.985  122.646 1.00 44.53  ? 392 LEU A CG  1 
ATOM   2916 C CD1 . LEU A 1 392 ? 129.170 97.447  122.426 1.00 44.53  ? 392 LEU A CD1 1 
ATOM   2917 C CD2 . LEU A 1 392 ? 127.461 95.715  121.860 1.00 44.53  ? 392 LEU A CD2 1 
ATOM   2918 N N   . GLY A 1 393 ? 126.065 99.065  125.861 1.00 42.49  ? 393 GLY A N   1 
ATOM   2919 C CA  . GLY A 1 393 ? 125.163 100.193 125.933 1.00 42.49  ? 393 GLY A CA  1 
ATOM   2920 C C   . GLY A 1 393 ? 123.932 100.004 125.062 1.00 42.49  ? 393 GLY A C   1 
ATOM   2921 O O   . GLY A 1 393 ? 123.913 99.221  124.111 1.00 42.49  ? 393 GLY A O   1 
ATOM   2922 N N   . GLY A 1 394 ? 122.878 100.746 125.405 1.00 39.63  ? 394 GLY A N   1 
ATOM   2923 C CA  . GLY A 1 394 ? 121.630 100.624 124.668 1.00 39.63  ? 394 GLY A CA  1 
ATOM   2924 C C   . GLY A 1 394 ? 121.716 101.198 123.266 1.00 39.63  ? 394 GLY A C   1 
ATOM   2925 O O   . GLY A 1 394 ? 121.363 100.532 122.288 1.00 39.63  ? 394 GLY A O   1 
ATOM   2926 N N   . GLY A 1 395 ? 122.177 102.444 123.150 1.00 35.12  ? 395 GLY A N   1 
ATOM   2927 C CA  . GLY A 1 395 ? 122.233 103.083 121.845 1.00 35.12  ? 395 GLY A CA  1 
ATOM   2928 C C   . GLY A 1 395 ? 123.256 102.461 120.913 1.00 35.12  ? 395 GLY A C   1 
ATOM   2929 O O   . GLY A 1 395 ? 123.018 102.345 119.708 1.00 35.12  ? 395 GLY A O   1 
ATOM   2930 N N   . THR A 1 396 ? 124.408 102.058 121.454 1.00 35.33  ? 396 THR A N   1 
ATOM   2931 C CA  . THR A 1 396 ? 125.488 101.549 120.613 1.00 35.33  ? 396 THR A CA  1 
ATOM   2932 C C   . THR A 1 396 ? 125.106 100.237 119.938 1.00 35.33  ? 396 THR A C   1 
ATOM   2933 O O   . THR A 1 396 ? 125.465 100.002 118.778 1.00 35.33  ? 396 THR A O   1 
ATOM   2934 C CB  . THR A 1 396 ? 126.759 101.375 121.443 1.00 35.33  ? 396 THR A CB  1 
ATOM   2935 O OG1 . THR A 1 396 ? 126.938 102.517 122.288 1.00 35.33  ? 396 THR A OG1 1 
ATOM   2936 C CG2 . THR A 1 396 ? 127.968 101.228 120.536 1.00 35.33  ? 396 THR A CG2 1 
ATOM   2937 N N   . ALA A 1 397 ? 124.388 99.364  120.649 1.00 34.03  ? 397 ALA A N   1 
ATOM   2938 C CA  . ALA A 1 397 ? 123.989 98.087  120.065 1.00 34.03  ? 397 ALA A CA  1 
ATOM   2939 C C   . ALA A 1 397 ? 122.980 98.270  118.938 1.00 34.03  ? 397 ALA A C   1 
ATOM   2940 O O   . ALA A 1 397 ? 122.898 97.426  118.036 1.00 34.03  ? 397 ALA A O   1 
ATOM   2941 C CB  . ALA A 1 397 ? 123.416 97.172  121.145 1.00 34.03  ? 397 ALA A CB  1 
ATOM   2942 N N   . SER A 1 398 ? 122.207 99.358  118.974 1.00 30.41  ? 398 SER A N   1 
ATOM   2943 C CA  . SER A 1 398 ? 121.228 99.608  117.921 1.00 30.41  ? 398 SER A CA  1 
ATOM   2944 C C   . SER A 1 398 ? 121.909 99.851  116.581 1.00 30.41  ? 398 SER A C   1 
ATOM   2945 O O   . SER A 1 398 ? 121.390 99.449  115.533 1.00 30.41  ? 398 SER A O   1 
ATOM   2946 C CB  . SER A 1 398 ? 120.345 100.795 118.298 1.00 30.41  ? 398 SER A CB  1 
ATOM   2947 O OG  . SER A 1 398 ? 119.482 101.140 117.231 1.00 30.41  ? 398 SER A OG  1 
ATOM   2948 N N   . LEU A 1 399 ? 123.067 100.514 116.593 1.00 31.56  ? 399 LEU A N   1 
ATOM   2949 C CA  . LEU A 1 399 ? 123.821 100.726 115.361 1.00 31.56  ? 399 LEU A CA  1 
ATOM   2950 C C   . LEU A 1 399 ? 124.241 99.400  114.738 1.00 31.56  ? 399 LEU A C   1 
ATOM   2951 O O   . LEU A 1 399 ? 124.102 99.197  113.526 1.00 31.56  ? 399 LEU A O   1 
ATOM   2952 C CB  . LEU A 1 399 ? 125.044 101.597 115.645 1.00 31.56  ? 399 LEU A CB  1 
ATOM   2953 C CG  . LEU A 1 399 ? 125.884 102.028 114.444 1.00 31.56  ? 399 LEU A CG  1 
ATOM   2954 C CD1 . LEU A 1 399 ? 125.273 103.243 113.777 1.00 31.56  ? 399 LEU A CD1 1 
ATOM   2955 C CD2 . LEU A 1 399 ? 127.309 102.314 114.875 1.00 31.56  ? 399 LEU A CD2 1 
ATOM   2956 N N   . ILE A 1 400 ? 124.745 98.479  115.562 1.00 31.34  ? 400 ILE A N   1 
ATOM   2957 C CA  . ILE A 1 400 ? 125.156 97.170  115.063 1.00 31.34  ? 400 ILE A CA  1 
ATOM   2958 C C   . ILE A 1 400 ? 123.952 96.391  114.548 1.00 31.34  ? 400 ILE A C   1 
ATOM   2959 O O   . ILE A 1 400 ? 124.029 95.712  113.516 1.00 31.34  ? 400 ILE A O   1 
ATOM   2960 C CB  . ILE A 1 400 ? 125.907 96.394  116.159 1.00 31.34  ? 400 ILE A CB  1 
ATOM   2961 C CG1 . ILE A 1 400 ? 127.058 97.235  116.709 1.00 31.34  ? 400 ILE A CG1 1 
ATOM   2962 C CG2 . ILE A 1 400 ? 126.426 95.073  115.620 1.00 31.34  ? 400 ILE A CG2 1 
ATOM   2963 C CD1 . ILE A 1 400 ? 127.844 96.550  117.802 1.00 31.34  ? 400 ILE A CD1 1 
ATOM   2964 N N   . VAL A 1 401 ? 122.825 96.471  115.261 1.00 32.55  ? 401 VAL A N   1 
ATOM   2965 C CA  . VAL A 1 401 ? 121.620 95.761  114.835 1.00 32.55  ? 401 VAL A CA  1 
ATOM   2966 C C   . VAL A 1 401 ? 121.143 96.284  113.484 1.00 32.55  ? 401 VAL A C   1 
ATOM   2967 O O   . VAL A 1 401 ? 120.801 95.508  112.585 1.00 32.55  ? 401 VAL A O   1 
ATOM   2968 C CB  . VAL A 1 401 ? 120.523 95.872  115.908 1.00 32.55  ? 401 VAL A CB  1 
ATOM   2969 C CG1 . VAL A 1 401 ? 119.159 95.549  115.320 1.00 32.55  ? 401 VAL A CG1 1 
ATOM   2970 C CG2 . VAL A 1 401 ? 120.831 94.943  117.067 1.00 32.55  ? 401 VAL A CG2 1 
ATOM   2971 N N   . GLY A 1 402 ? 121.130 97.608  113.318 1.00 33.96  ? 402 GLY A N   1 
ATOM   2972 C CA  . GLY A 1 402 ? 120.733 98.180  112.042 1.00 33.96  ? 402 GLY A CA  1 
ATOM   2973 C C   . GLY A 1 402 ? 121.683 97.817  110.917 1.00 33.96  ? 402 GLY A C   1 
ATOM   2974 O O   . GLY A 1 402 ? 121.251 97.524  109.799 1.00 33.96  ? 402 GLY A O   1 
ATOM   2975 N N   . LEU A 1 403 ? 122.989 97.827  111.201 1.00 37.11  ? 403 LEU A N   1 
ATOM   2976 C CA  . LEU A 1 403 ? 123.979 97.433  110.202 1.00 37.11  ? 403 LEU A CA  1 
ATOM   2977 C C   . LEU A 1 403 ? 123.747 95.999  109.739 1.00 37.11  ? 403 LEU A C   1 
ATOM   2978 O O   . LEU A 1 403 ? 123.703 95.717  108.533 1.00 37.11  ? 403 LEU A O   1 
ATOM   2979 C CB  . LEU A 1 403 ? 125.383 97.581  110.789 1.00 37.11  ? 403 LEU A CB  1 
ATOM   2980 C CG  . LEU A 1 403 ? 126.517 98.101  109.909 1.00 37.11  ? 403 LEU A CG  1 
ATOM   2981 C CD1 . LEU A 1 403 ? 126.184 99.482  109.385 1.00 37.11  ? 403 LEU A CD1 1 
ATOM   2982 C CD2 . LEU A 1 403 ? 127.826 98.120  110.680 1.00 37.11  ? 403 LEU A CD2 1 
ATOM   2983 N N   . VAL A 1 404 ? 123.583 95.082  110.696 1.00 38.23  ? 404 VAL A N   1 
ATOM   2984 C CA  . VAL A 1 404 ? 123.383 93.673  110.368 1.00 38.23  ? 404 VAL A CA  1 
ATOM   2985 C C   . VAL A 1 404 ? 122.082 93.481  109.601 1.00 38.23  ? 404 VAL A C   1 
ATOM   2986 O O   . VAL A 1 404 ? 122.030 92.725  108.623 1.00 38.23  ? 404 VAL A O   1 
ATOM   2987 C CB  . VAL A 1 404 ? 123.424 92.819  111.649 1.00 38.23  ? 404 VAL A CB  1 
ATOM   2988 C CG1 . VAL A 1 404 ? 122.918 91.412  111.378 1.00 38.23  ? 404 VAL A CG1 1 
ATOM   2989 C CG2 . VAL A 1 404 ? 124.836 92.778  112.207 1.00 38.23  ? 404 VAL A CG2 1 
ATOM   2990 N N   . GLN A 1 405 ? 121.013 94.159  110.028 1.00 44.30  ? 405 GLN A N   1 
ATOM   2991 C CA  . GLN A 1 405 ? 119.729 94.014  109.351 1.00 44.30  ? 405 GLN A CA  1 
ATOM   2992 C C   . GLN A 1 405 ? 119.795 94.517  107.916 1.00 44.30  ? 405 GLN A C   1 
ATOM   2993 O O   . GLN A 1 405 ? 119.274 93.867  107.003 1.00 44.30  ? 405 GLN A O   1 
ATOM   2994 C CB  . GLN A 1 405 ? 118.636 94.747  110.126 1.00 44.30  ? 405 GLN A CB  1 
ATOM   2995 C CG  . GLN A 1 405 ? 117.639 93.822  110.801 1.00 44.30  ? 405 GLN A CG  1 
ATOM   2996 C CD  . GLN A 1 405 ? 116.352 94.526  111.173 1.00 44.30  ? 405 GLN A CD  1 
ATOM   2997 O OE1 . GLN A 1 405 ? 115.658 95.070  110.314 1.00 44.30  ? 405 GLN A OE1 1 
ATOM   2998 N NE2 . GLN A 1 405 ? 116.027 94.523  112.460 1.00 44.30  ? 405 GLN A NE2 1 
ATOM   2999 N N   . SER A 1 406 ? 120.437 95.667  107.692 1.00 46.26  ? 406 SER A N   1 
ATOM   3000 C CA  . SER A 1 406 ? 120.564 96.182  106.332 1.00 46.26  ? 406 SER A CA  1 
ATOM   3001 C C   . SER A 1 406 ? 121.392 95.247  105.459 1.00 46.26  ? 406 SER A C   1 
ATOM   3002 O O   . SER A 1 406 ? 121.018 94.960  104.314 1.00 46.26  ? 406 SER A O   1 
ATOM   3003 C CB  . SER A 1 406 ? 121.180 97.579  106.351 1.00 46.26  ? 406 SER A CB  1 
ATOM   3004 O OG  . SER A 1 406 ? 121.521 97.994  105.041 1.00 46.26  ? 406 SER A OG  1 
ATOM   3005 N N   . ILE A 1 407 ? 122.514 94.749  105.990 1.00 52.80  ? 407 ILE A N   1 
ATOM   3006 C CA  . ILE A 1 407 ? 123.372 93.859  105.210 1.00 52.80  ? 407 ILE A CA  1 
ATOM   3007 C C   . ILE A 1 407 ? 122.634 92.571  104.858 1.00 52.80  ? 407 ILE A C   1 
ATOM   3008 O O   . ILE A 1 407 ? 122.703 92.089  103.721 1.00 52.80  ? 407 ILE A O   1 
ATOM   3009 C CB  . ILE A 1 407 ? 124.681 93.580  105.971 1.00 52.80  ? 407 ILE A CB  1 
ATOM   3010 C CG1 . ILE A 1 407 ? 125.589 94.810  105.929 1.00 52.80  ? 407 ILE A CG1 1 
ATOM   3011 C CG2 . ILE A 1 407 ? 125.397 92.367  105.398 1.00 52.80  ? 407 ILE A CG2 1 
ATOM   3012 C CD1 . ILE A 1 407 ? 126.941 94.594  106.574 1.00 52.80  ? 407 ILE A CD1 1 
ATOM   3013 N N   . TYR A 1 408 ? 121.903 92.004  105.819 1.00 62.17  ? 408 TYR A N   1 
ATOM   3014 C CA  . TYR A 1 408 ? 121.196 90.753  105.572 1.00 62.17  ? 408 TYR A CA  1 
ATOM   3015 C C   . TYR A 1 408 ? 120.010 90.950  104.632 1.00 62.17  ? 408 TYR A C   1 
ATOM   3016 O O   . TYR A 1 408 ? 119.721 90.070  103.812 1.00 62.17  ? 408 TYR A O   1 
ATOM   3017 C CB  . TYR A 1 408 ? 120.757 90.147  106.906 1.00 62.17  ? 408 TYR A CB  1 
ATOM   3018 C CG  . TYR A 1 408 ? 119.688 89.083  106.819 1.00 62.17  ? 408 TYR A CG  1 
ATOM   3019 C CD1 . TYR A 1 408 ? 119.904 87.905  106.117 1.00 62.17  ? 408 TYR A CD1 1 
ATOM   3020 C CD2 . TYR A 1 408 ? 118.470 89.246  107.466 1.00 62.17  ? 408 TYR A CD2 1 
ATOM   3021 C CE1 . TYR A 1 408 ? 118.930 86.927  106.045 1.00 62.17  ? 408 TYR A CE1 1 
ATOM   3022 C CE2 . TYR A 1 408 ? 117.493 88.275  107.403 1.00 62.17  ? 408 TYR A CE2 1 
ATOM   3023 C CZ  . TYR A 1 408 ? 117.726 87.119  106.690 1.00 62.17  ? 408 TYR A CZ  1 
ATOM   3024 O OH  . TYR A 1 408 ? 116.751 86.150  106.625 1.00 62.17  ? 408 TYR A OH  1 
ATOM   3025 N N   . ARG A 1 409 ? 119.322 92.093  104.721 1.00 64.03  ? 409 ARG A N   1 
ATOM   3026 C CA  . ARG A 1 409 ? 118.211 92.358  103.813 1.00 64.03  ? 409 ARG A CA  1 
ATOM   3027 C C   . ARG A 1 409 ? 118.698 92.634  102.397 1.00 64.03  ? 409 ARG A C   1 
ATOM   3028 O O   . ARG A 1 409 ? 117.967 92.378  101.433 1.00 64.03  ? 409 ARG A O   1 
ATOM   3029 C CB  . ARG A 1 409 ? 117.380 93.537  104.320 1.00 64.03  ? 409 ARG A CB  1 
ATOM   3030 C CG  . ARG A 1 409 ? 116.105 93.780  103.526 1.00 64.03  ? 409 ARG A CG  1 
ATOM   3031 C CD  . ARG A 1 409 ? 115.627 95.222  103.652 1.00 64.03  ? 409 ARG A CD  1 
ATOM   3032 N NE  . ARG A 1 409 ? 116.569 96.202  103.117 1.00 64.03  ? 409 ARG A NE  1 
ATOM   3033 C CZ  . ARG A 1 409 ? 117.003 96.258  101.862 1.00 64.03  ? 409 ARG A CZ  1 
ATOM   3034 N NH1 . ARG A 1 409 ? 116.548 95.438  100.928 1.00 64.03  ? 409 ARG A NH1 1 
ATOM   3035 N NH2 . ARG A 1 409 ? 117.904 97.179  101.530 1.00 64.03  ? 409 ARG A NH2 1 
ATOM   3036 N N   . ASP A 1 410 ? 119.915 93.167  102.251 1.00 69.74  ? 410 ASP A N   1 
ATOM   3037 C CA  . ASP A 1 410 ? 120.469 93.378  100.917 1.00 69.74  ? 410 ASP A CA  1 
ATOM   3038 C C   . ASP A 1 410 ? 120.580 92.049  100.176 1.00 69.74  ? 410 ASP A C   1 
ATOM   3039 O O   . ASP A 1 410 ? 120.198 91.947  99.004  1.00 69.74  ? 410 ASP A O   1 
ATOM   3040 C CB  . ASP A 1 410 ? 121.831 94.077  101.041 1.00 69.74  ? 410 ASP A CB  1 
ATOM   3041 C CG  . ASP A 1 410 ? 122.652 94.078  99.744  1.00 69.74  ? 410 ASP A CG  1 
ATOM   3042 O OD1 . ASP A 1 410 ? 122.116 93.852  98.639  1.00 69.74  ? 410 ASP A OD1 1 
ATOM   3043 O OD2 . ASP A 1 410 ? 123.874 94.314  99.842  1.00 69.74  ? 410 ASP A OD2 1 
ATOM   3044 N N   . LYS A 1 411 ? 121.063 91.008  100.856 1.00 77.01  ? 411 LYS A N   1 
ATOM   3045 C CA  . LYS A 1 411 ? 121.194 89.697  100.229 1.00 77.01  ? 411 LYS A CA  1 
ATOM   3046 C C   . LYS A 1 411 ? 119.844 88.993  100.121 1.00 77.01  ? 411 LYS A C   1 
ATOM   3047 O O   . LYS A 1 411 ? 119.398 88.653  99.020  1.00 77.01  ? 411 LYS A O   1 
ATOM   3048 C CB  . LYS A 1 411 ? 122.194 88.841  101.009 1.00 77.01  ? 411 LYS A CB  1 
ATOM   3049 C CG  . LYS A 1 411 ? 123.607 89.402  101.008 1.00 77.01  ? 411 LYS A CG  1 
ATOM   3050 C CD  . LYS A 1 411 ? 124.505 88.659  101.981 1.00 77.01  ? 411 LYS A CD  1 
ATOM   3051 C CE  . LYS A 1 411 ? 125.800 89.419  102.216 1.00 77.01  ? 411 LYS A CE  1 
ATOM   3052 N NZ  . LYS A 1 411 ? 126.982 88.515  102.246 1.00 77.01  ? 411 LYS A NZ  1 
ATOM   3053 N N   . HIS A 1 412 ? 119.178 88.766  101.251 1.00 87.83  ? 412 HIS A N   1 
ATOM   3054 C CA  . HIS A 1 412 ? 117.888 88.085  101.257 1.00 87.83  ? 412 HIS A CA  1 
ATOM   3055 C C   . HIS A 1 412 ? 116.771 89.119  101.170 1.00 87.83  ? 412 HIS A C   1 
ATOM   3056 O O   . HIS A 1 412 ? 116.628 89.963  102.060 1.00 87.83  ? 412 HIS A O   1 
ATOM   3057 C CB  . HIS A 1 412 ? 117.736 87.222  102.508 1.00 87.83  ? 412 HIS A CB  1 
ATOM   3058 C CG  . HIS A 1 412 ? 118.258 85.830  102.344 1.00 87.83  ? 412 HIS A CG  1 
ATOM   3059 N ND1 . HIS A 1 412 ? 119.554 85.563  101.958 1.00 87.83  ? 412 HIS A ND1 1 
ATOM   3060 C CD2 . HIS A 1 412 ? 117.659 84.626  102.508 1.00 87.83  ? 412 HIS A CD2 1 
ATOM   3061 C CE1 . HIS A 1 412 ? 119.732 84.255  101.893 1.00 87.83  ? 412 HIS A CE1 1 
ATOM   3062 N NE2 . HIS A 1 412 ? 118.597 83.664  102.223 1.00 87.83  ? 412 HIS A NE2 1 
ATOM   3063 N N   . ALA A 1 413 ? 115.973 89.039  100.106 1.00 104.58 ? 413 ALA A N   1 
ATOM   3064 C CA  . ALA A 1 413 ? 114.962 90.041  99.801  1.00 104.58 ? 413 ALA A CA  1 
ATOM   3065 C C   . ALA A 1 413 ? 113.570 89.657  100.285 1.00 104.58 ? 413 ALA A C   1 
ATOM   3066 O O   . ALA A 1 413 ? 112.591 90.291  99.879  1.00 104.58 ? 413 ALA A O   1 
ATOM   3067 C CB  . ALA A 1 413 ? 114.931 90.314  98.296  1.00 104.58 ? 413 ALA A CB  1 
ATOM   3068 N N   . HIS A 1 414 ? 113.455 88.626  101.127 1.00 113.16 ? 414 HIS A N   1 
ATOM   3069 C CA  . HIS A 1 414 ? 112.151 88.261  101.673 1.00 113.16 ? 414 HIS A CA  1 
ATOM   3070 C C   . HIS A 1 414 ? 111.581 89.384  102.531 1.00 113.16 ? 414 HIS A C   1 
ATOM   3071 O O   . HIS A 1 414 ? 110.385 89.691  102.454 1.00 113.16 ? 414 HIS A O   1 
ATOM   3072 C CB  . HIS A 1 414 ? 112.250 86.968  102.488 1.00 113.16 ? 414 HIS A CB  1 
ATOM   3073 C CG  . HIS A 1 414 ? 112.958 85.850  101.785 1.00 113.16 ? 414 HIS A CG  1 
ATOM   3074 N ND1 . HIS A 1 414 ? 114.305 85.880  101.496 1.00 113.16 ? 414 HIS A ND1 1 
ATOM   3075 C CD2 . HIS A 1 414 ? 112.500 84.665  101.315 1.00 113.16 ? 414 HIS A CD2 1 
ATOM   3076 C CE1 . HIS A 1 414 ? 114.647 84.763  100.878 1.00 113.16 ? 414 HIS A CE1 1 
ATOM   3077 N NE2 . HIS A 1 414 ? 113.570 84.009  100.756 1.00 113.16 ? 414 HIS A NE2 1 
ATOM   3078 N N   . MET A 1 415 ? 112.419 90.006  103.354 1.00 96.71  ? 415 MET A N   1 
ATOM   3079 C CA  . MET A 1 415 ? 111.991 91.116  104.189 1.00 96.71  ? 415 MET A CA  1 
ATOM   3080 C C   . MET A 1 415 ? 111.880 92.395  103.369 1.00 96.71  ? 415 MET A C   1 
ATOM   3081 O O   . MET A 1 415 ? 112.626 92.613  102.410 1.00 96.71  ? 415 MET A O   1 
ATOM   3082 C CB  . MET A 1 415 ? 112.964 91.322  105.350 1.00 96.71  ? 415 MET A CB  1 
ATOM   3083 C CG  . MET A 1 415 ? 112.970 90.192  106.368 1.00 96.71  ? 415 MET A CG  1 
ATOM   3084 S SD  . MET A 1 415 ? 113.237 88.566  105.635 1.00 96.71  ? 415 MET A SD  1 
ATOM   3085 C CE  . MET A 1 415 ? 114.918 88.725  105.037 1.00 96.71  ? 415 MET A CE  1 
ATOM   3086 N N   . ASP A 1 416 ? 110.934 93.244  103.758 1.00 90.54  ? 416 ASP A N   1 
ATOM   3087 C CA  . ASP A 1 416 ? 110.708 94.502  103.067 1.00 90.54  ? 416 ASP A CA  1 
ATOM   3088 C C   . ASP A 1 416 ? 111.652 95.581  103.595 1.00 90.54  ? 416 ASP A C   1 
ATOM   3089 O O   . ASP A 1 416 ? 112.370 95.393  104.581 1.00 90.54  ? 416 ASP A O   1 
ATOM   3090 C CB  . ASP A 1 416 ? 109.251 94.929  103.217 1.00 90.54  ? 416 ASP A CB  1 
ATOM   3091 C CG  . ASP A 1 416 ? 108.288 93.780  103.002 1.00 90.54  ? 416 ASP A CG  1 
ATOM   3092 O OD1 . ASP A 1 416 ? 108.322 92.820  103.799 1.00 90.54  ? 416 ASP A OD1 1 
ATOM   3093 O OD2 . ASP A 1 416 ? 107.506 93.828  102.030 1.00 90.54  ? 416 ASP A OD2 1 
ATOM   3094 N N   . THR A 1 417 ? 111.643 96.730  102.924 1.00 79.04  ? 417 THR A N   1 
ATOM   3095 C CA  . THR A 1 417 ? 112.563 97.819  103.216 1.00 79.04  ? 417 THR A CA  1 
ATOM   3096 C C   . THR A 1 417 ? 111.817 99.000  103.825 1.00 79.04  ? 417 THR A C   1 
ATOM   3097 O O   . THR A 1 417 ? 110.681 99.295  103.443 1.00 79.04  ? 417 THR A O   1 
ATOM   3098 C CB  . THR A 1 417 ? 113.296 98.277  101.953 1.00 79.04  ? 417 THR A CB  1 
ATOM   3099 O OG1 . THR A 1 417 ? 112.469 99.195  101.229 1.00 79.04  ? 417 THR A OG1 1 
ATOM   3100 C CG2 . THR A 1 417 ? 113.612 97.088  101.064 1.00 79.04  ? 417 THR A CG2 1 
ATOM   3101 N N   . ILE A 1 418 ? 112.468 99.667  104.769 1.00 57.97  ? 418 ILE A N   1 
ATOM   3102 C CA  . ILE A 1 418 ? 111.880 100.834 105.437 1.00 57.97  ? 418 ILE A CA  1 
ATOM   3103 C C   . ILE A 1 418 ? 111.908 102.024 104.484 1.00 57.97  ? 418 ILE A C   1 
ATOM   3104 O O   . ILE A 1 418 ? 112.914 102.220 103.778 1.00 57.97  ? 418 ILE A O   1 
ATOM   3105 C CB  . ILE A 1 418 ? 112.639 101.136 106.736 1.00 57.97  ? 418 ILE A CB  1 
ATOM   3106 C CG1 . ILE A 1 418 ? 112.227 100.162 107.847 1.00 57.97  ? 418 ILE A CG1 1 
ATOM   3107 C CG2 . ILE A 1 418 ? 112.416 102.564 107.197 1.00 57.97  ? 418 ILE A CG2 1 
ATOM   3108 C CD1 . ILE A 1 418 ? 112.986 98.850  107.853 1.00 57.97  ? 418 ILE A CD1 1 
ATOM   3109 N N   . PRO A 1 419 ? 110.842 102.824 104.407 1.00 58.41  ? 419 PRO A N   1 
ATOM   3110 C CA  . PRO A 1 419 ? 110.854 103.993 103.517 1.00 58.41  ? 419 PRO A CA  1 
ATOM   3111 C C   . PRO A 1 419 ? 111.908 105.012 103.928 1.00 58.41  ? 419 PRO A C   1 
ATOM   3112 O O   . PRO A 1 419 ? 112.316 105.088 105.088 1.00 58.41  ? 419 PRO A O   1 
ATOM   3113 C CB  . PRO A 1 419 ? 109.439 104.563 103.664 1.00 58.41  ? 419 PRO A CB  1 
ATOM   3114 C CG  . PRO A 1 419 ? 108.614 103.401 104.101 1.00 58.41  ? 419 PRO A CG  1 
ATOM   3115 C CD  . PRO A 1 419 ? 109.511 102.594 104.991 1.00 58.41  ? 419 PRO A CD  1 
ATOM   3116 N N   . ASP A 1 420 ? 112.346 105.804 102.946 1.00 59.08  ? 420 ASP A N   1 
ATOM   3117 C CA  . ASP A 1 420 ? 113.508 106.668 103.137 1.00 59.08  ? 420 ASP A CA  1 
ATOM   3118 C C   . ASP A 1 420 ? 113.206 107.827 104.083 1.00 59.08  ? 420 ASP A C   1 
ATOM   3119 O O   . ASP A 1 420 ? 114.006 108.132 104.976 1.00 59.08  ? 420 ASP A O   1 
ATOM   3120 C CB  . ASP A 1 420 ? 113.995 107.186 101.784 1.00 59.08  ? 420 ASP A CB  1 
ATOM   3121 C CG  . ASP A 1 420 ? 115.398 107.756 101.848 1.00 59.08  ? 420 ASP A CG  1 
ATOM   3122 O OD1 . ASP A 1 420 ? 115.582 108.831 102.456 1.00 59.08  ? 420 ASP A OD1 1 
ATOM   3123 O OD2 . ASP A 1 420 ? 116.320 107.123 101.293 1.00 59.08  ? 420 ASP A OD2 1 
ATOM   3124 N N   . SER A 1 421 ? 112.063 108.495 103.897 1.00 53.48  ? 421 SER A N   1 
ATOM   3125 C CA  . SER A 1 421 ? 111.748 109.667 104.713 1.00 53.48  ? 421 SER A CA  1 
ATOM   3126 C C   . SER A 1 421 ? 111.541 109.300 106.178 1.00 53.48  ? 421 SER A C   1 
ATOM   3127 O O   . SER A 1 421 ? 111.760 110.135 107.069 1.00 53.48  ? 421 SER A O   1 
ATOM   3128 C CB  . SER A 1 421 ? 110.507 110.368 104.164 1.00 53.48  ? 421 SER A CB  1 
ATOM   3129 O OG  . SER A 1 421 ? 109.448 109.448 103.976 1.00 53.48  ? 421 SER A OG  1 
ATOM   3130 N N   . LEU A 1 422 ? 111.121 108.060 106.441 1.00 46.57  ? 422 LEU A N   1 
ATOM   3131 C CA  . LEU A 1 422 ? 110.947 107.600 107.813 1.00 46.57  ? 422 LEU A CA  1 
ATOM   3132 C C   . LEU A 1 422 ? 112.263 107.645 108.577 1.00 46.57  ? 422 LEU A C   1 
ATOM   3133 O O   . LEU A 1 422 ? 112.296 108.051 109.744 1.00 46.57  ? 422 LEU A O   1 
ATOM   3134 C CB  . LEU A 1 422 ? 110.371 106.185 107.815 1.00 46.57  ? 422 LEU A CB  1 
ATOM   3135 C CG  . LEU A 1 422 ? 109.886 105.634 109.153 1.00 46.57  ? 422 LEU A CG  1 
ATOM   3136 C CD1 . LEU A 1 422 ? 108.644 106.370 109.597 1.00 46.57  ? 422 LEU A CD1 1 
ATOM   3137 C CD2 . LEU A 1 422 ? 109.614 104.145 109.050 1.00 46.57  ? 422 LEU A CD2 1 
ATOM   3138 N N   . LEU A 1 423 ? 113.360 107.245 107.930 1.00 43.63  ? 423 LEU A N   1 
ATOM   3139 C CA  . LEU A 1 423 ? 114.664 107.265 108.584 1.00 43.63  ? 423 LEU A CA  1 
ATOM   3140 C C   . LEU A 1 423 ? 115.095 108.686 108.931 1.00 43.63  ? 423 LEU A C   1 
ATOM   3141 O O   . LEU A 1 423 ? 115.630 108.932 110.021 1.00 43.63  ? 423 LEU A O   1 
ATOM   3142 C CB  . LEU A 1 423 ? 115.703 106.598 107.684 1.00 43.63  ? 423 LEU A CB  1 
ATOM   3143 C CG  . LEU A 1 423 ? 115.558 105.093 107.469 1.00 43.63  ? 423 LEU A CG  1 
ATOM   3144 C CD1 . LEU A 1 423 ? 116.827 104.525 106.863 1.00 43.63  ? 423 LEU A CD1 1 
ATOM   3145 C CD2 . LEU A 1 423 ? 115.231 104.393 108.777 1.00 43.63  ? 423 LEU A CD2 1 
ATOM   3146 N N   . GLU A 1 424 ? 114.887 109.630 108.009 1.00 44.95  ? 424 GLU A N   1 
ATOM   3147 C CA  . GLU A 1 424 ? 115.274 111.015 108.258 1.00 44.95  ? 424 GLU A CA  1 
ATOM   3148 C C   . GLU A 1 424 ? 114.467 111.611 109.404 1.00 44.95  ? 424 GLU A C   1 
ATOM   3149 O O   . GLU A 1 424 ? 115.024 112.262 110.303 1.00 44.95  ? 424 GLU A O   1 
ATOM   3150 C CB  . GLU A 1 424 ? 115.101 111.841 106.984 1.00 44.95  ? 424 GLU A CB  1 
ATOM   3151 C CG  . GLU A 1 424 ? 115.614 113.265 107.096 1.00 44.95  ? 424 GLU A CG  1 
ATOM   3152 C CD  . GLU A 1 424 ? 115.501 114.030 105.793 1.00 44.95  ? 424 GLU A CD  1 
ATOM   3153 O OE1 . GLU A 1 424 ? 116.069 113.568 104.781 1.00 44.95  ? 424 GLU A OE1 1 
ATOM   3154 O OE2 . GLU A 1 424 ? 114.850 115.095 105.781 1.00 44.95  ? 424 GLU A OE2 1 
ATOM   3155 N N   . PHE A 1 425 ? 113.146 111.395 109.385 1.00 41.31  ? 425 PHE A N   1 
ATOM   3156 C CA  . PHE A 1 425 ? 112.305 111.807 110.505 1.00 41.31  ? 425 PHE A CA  1 
ATOM   3157 C C   . PHE A 1 425 ? 112.811 111.215 111.812 1.00 41.31  ? 425 PHE A C   1 
ATOM   3158 O O   . PHE A 1 425 ? 112.946 111.925 112.821 1.00 41.31  ? 425 PHE A O   1 
ATOM   3159 C CB  . PHE A 1 425 ? 110.857 111.384 110.249 1.00 41.31  ? 425 PHE A CB  1 
ATOM   3160 C CG  . PHE A 1 425 ? 110.024 111.270 111.497 1.00 41.31  ? 425 PHE A CG  1 
ATOM   3161 C CD1 . PHE A 1 425 ? 109.392 112.377 112.029 1.00 41.31  ? 425 PHE A CD1 1 
ATOM   3162 C CD2 . PHE A 1 425 ? 109.858 110.044 112.126 1.00 41.31  ? 425 PHE A CD2 1 
ATOM   3163 C CE1 . PHE A 1 425 ? 108.625 112.264 113.169 1.00 41.31  ? 425 PHE A CE1 1 
ATOM   3164 C CE2 . PHE A 1 425 ? 109.099 109.932 113.268 1.00 41.31  ? 425 PHE A CE2 1 
ATOM   3165 C CZ  . PHE A 1 425 ? 108.485 111.043 113.791 1.00 41.31  ? 425 PHE A CZ  1 
ATOM   3166 N N   . PHE A 1 426 ? 113.095 109.909 111.805 1.00 39.98  ? 426 PHE A N   1 
ATOM   3167 C CA  . PHE A 1 426 ? 113.592 109.215 112.985 1.00 39.98  ? 426 PHE A CA  1 
ATOM   3168 C C   . PHE A 1 426 ? 114.809 109.914 113.560 1.00 39.98  ? 426 PHE A C   1 
ATOM   3169 O O   . PHE A 1 426 ? 114.789 110.382 114.703 1.00 39.98  ? 426 PHE A O   1 
ATOM   3170 C CB  . PHE A 1 426 ? 113.939 107.771 112.627 1.00 39.98  ? 426 PHE A CB  1 
ATOM   3171 C CG  . PHE A 1 426 ? 112.819 106.807 112.835 1.00 39.98  ? 426 PHE A CG  1 
ATOM   3172 C CD1 . PHE A 1 426 ? 111.919 106.984 113.871 1.00 39.98  ? 426 PHE A CD1 1 
ATOM   3173 C CD2 . PHE A 1 426 ? 112.669 105.717 111.998 1.00 39.98  ? 426 PHE A CD2 1 
ATOM   3174 C CE1 . PHE A 1 426 ? 110.889 106.092 114.063 1.00 39.98  ? 426 PHE A CE1 1 
ATOM   3175 C CE2 . PHE A 1 426 ? 111.643 104.824 112.185 1.00 39.98  ? 426 PHE A CE2 1 
ATOM   3176 C CZ  . PHE A 1 426 ? 110.753 105.010 113.218 1.00 39.98  ? 426 PHE A CZ  1 
ATOM   3177 N N   . GLN A 1 427 ? 115.876 110.013 112.762 1.00 39.99  ? 427 GLN A N   1 
ATOM   3178 C CA  . GLN A 1 427 ? 117.128 110.547 113.290 1.00 39.99  ? 427 GLN A CA  1 
ATOM   3179 C C   . GLN A 1 427 ? 116.949 111.980 113.776 1.00 39.99  ? 427 GLN A C   1 
ATOM   3180 O O   . GLN A 1 427 ? 117.301 112.303 114.921 1.00 39.99  ? 427 GLN A O   1 
ATOM   3181 C CB  . GLN A 1 427 ? 118.249 110.449 112.249 1.00 39.99  ? 427 GLN A CB  1 
ATOM   3182 C CG  . GLN A 1 427 ? 117.922 110.925 110.853 1.00 39.99  ? 427 GLN A CG  1 
ATOM   3183 C CD  . GLN A 1 427 ? 118.993 110.536 109.853 1.00 39.99  ? 427 GLN A CD  1 
ATOM   3184 O OE1 . GLN A 1 427 ? 119.287 109.355 109.671 1.00 39.99  ? 427 GLN A OE1 1 
ATOM   3185 N NE2 . GLN A 1 427 ? 119.587 111.530 109.203 1.00 39.99  ? 427 GLN A NE2 1 
ATOM   3186 N N   . SER A 1 428 ? 116.334 112.834 112.949 1.00 37.01  ? 428 SER A N   1 
ATOM   3187 C CA  . SER A 1 428 ? 116.198 114.243 113.305 1.00 37.01  ? 428 SER A CA  1 
ATOM   3188 C C   . SER A 1 428 ? 115.411 114.417 114.601 1.00 37.01  ? 428 SER A C   1 
ATOM   3189 O O   . SER A 1 428 ? 115.939 114.928 115.601 1.00 37.01  ? 428 SER A O   1 
ATOM   3190 C CB  . SER A 1 428 ? 115.534 115.006 112.159 1.00 37.01  ? 428 SER A CB  1 
ATOM   3191 O OG  . SER A 1 428 ? 115.375 116.375 112.484 1.00 37.01  ? 428 SER A OG  1 
ATOM   3192 N N   . ILE A 1 429 ? 114.144 113.988 114.606 1.00 31.65  ? 429 ILE A N   1 
ATOM   3193 C CA  . ILE A 1 429 ? 113.306 114.278 115.763 1.00 31.65  ? 429 ILE A CA  1 
ATOM   3194 C C   . ILE A 1 429 ? 113.765 113.509 116.996 1.00 31.65  ? 429 ILE A C   1 
ATOM   3195 O O   . ILE A 1 429 ? 113.703 114.042 118.108 1.00 31.65  ? 429 ILE A O   1 
ATOM   3196 C CB  . ILE A 1 429 ? 111.819 114.048 115.432 1.00 31.65  ? 429 ILE A CB  1 
ATOM   3197 C CG1 . ILE A 1 429 ? 111.244 115.326 114.818 1.00 31.65  ? 429 ILE A CG1 1 
ATOM   3198 C CG2 . ILE A 1 429 ? 111.017 113.633 116.656 1.00 31.65  ? 429 ILE A CG2 1 
ATOM   3199 C CD1 . ILE A 1 429 ? 109.802 115.233 114.418 1.00 31.65  ? 429 ILE A CD1 1 
ATOM   3200 N N   . GLY A 1 430 ? 114.264 112.278 116.844 1.00 29.59  ? 430 GLY A N   1 
ATOM   3201 C CA  . GLY A 1 430 ? 114.747 111.555 118.009 1.00 29.59  ? 430 GLY A CA  1 
ATOM   3202 C C   . GLY A 1 430 ? 115.924 112.238 118.679 1.00 29.59  ? 430 GLY A C   1 
ATOM   3203 O O   . GLY A 1 430 ? 115.944 112.409 119.906 1.00 29.59  ? 430 GLY A O   1 
ATOM   3204 N N   . LEU A 1 431 ? 116.919 112.655 117.886 1.00 29.15  ? 431 LEU A N   1 
ATOM   3205 C CA  . LEU A 1 431 ? 118.070 113.326 118.478 1.00 29.15  ? 431 LEU A CA  1 
ATOM   3206 C C   . LEU A 1 431 ? 117.669 114.645 119.125 1.00 29.15  ? 431 LEU A C   1 
ATOM   3207 O O   . LEU A 1 431 ? 118.086 114.944 120.255 1.00 29.15  ? 431 LEU A O   1 
ATOM   3208 C CB  . LEU A 1 431 ? 119.151 113.549 117.423 1.00 29.15  ? 431 LEU A CB  1 
ATOM   3209 C CG  . LEU A 1 431 ? 120.414 114.231 117.944 1.00 29.15  ? 431 LEU A CG  1 
ATOM   3210 C CD1 . LEU A 1 431 ? 121.042 113.389 119.036 1.00 29.15  ? 431 LEU A CD1 1 
ATOM   3211 C CD2 . LEU A 1 431 ? 121.399 114.468 116.813 1.00 29.15  ? 431 LEU A CD2 1 
ATOM   3212 N N   . ASN A 1 432 ? 116.837 115.440 118.439 1.00 25.36  ? 432 ASN A N   1 
ATOM   3213 C CA  . ASN A 1 432 ? 116.437 116.719 119.019 1.00 25.36  ? 432 ASN A CA  1 
ATOM   3214 C C   . ASN A 1 432 ? 115.594 116.531 120.275 1.00 25.36  ? 432 ASN A C   1 
ATOM   3215 O O   . ASN A 1 432 ? 115.705 117.318 121.219 1.00 25.36  ? 432 ASN A O   1 
ATOM   3216 C CB  . ASN A 1 432 ? 115.699 117.575 117.991 1.00 25.36  ? 432 ASN A CB  1 
ATOM   3217 C CG  . ASN A 1 432 ? 116.604 118.049 116.871 1.00 25.36  ? 432 ASN A CG  1 
ATOM   3218 O OD1 . ASN A 1 432 ? 116.518 117.579 115.740 1.00 25.36  ? 432 ASN A OD1 1 
ATOM   3219 N ND2 . ASN A 1 432 ? 117.490 118.983 117.190 1.00 25.36  ? 432 ASN A ND2 1 
ATOM   3220 N N   . LEU A 1 433 ? 114.764 115.486 120.321 1.00 29.45  ? 433 LEU A N   1 
ATOM   3221 C CA  . LEU A 1 433 ? 113.946 115.243 121.505 1.00 29.45  ? 433 LEU A CA  1 
ATOM   3222 C C   . LEU A 1 433 ? 114.803 114.827 122.692 1.00 29.45  ? 433 LEU A C   1 
ATOM   3223 O O   . LEU A 1 433 ? 114.567 115.280 123.819 1.00 29.45  ? 433 LEU A O   1 
ATOM   3224 C CB  . LEU A 1 433 ? 112.887 114.182 121.199 1.00 29.45  ? 433 LEU A CB  1 
ATOM   3225 C CG  . LEU A 1 433 ? 111.560 114.213 121.963 1.00 29.45  ? 433 LEU A CG  1 
ATOM   3226 C CD1 . LEU A 1 433 ? 110.530 113.383 121.224 1.00 29.45  ? 433 LEU A CD1 1 
ATOM   3227 C CD2 . LEU A 1 433 ? 111.702 113.706 123.388 1.00 29.45  ? 433 LEU A CD2 1 
ATOM   3228 N N   . PHE A 1 434 ? 115.796 113.961 122.466 1.00 24.47  ? 434 PHE A N   1 
ATOM   3229 C CA  . PHE A 1 434 ? 116.691 113.587 123.559 1.00 24.47  ? 434 PHE A CA  1 
ATOM   3230 C C   . PHE A 1 434 ? 117.447 114.803 124.083 1.00 24.47  ? 434 PHE A C   1 
ATOM   3231 O O   . PHE A 1 434 ? 117.576 114.992 125.304 1.00 24.47  ? 434 PHE A O   1 
ATOM   3232 C CB  . PHE A 1 434 ? 117.656 112.494 123.092 1.00 24.47  ? 434 PHE A CB  1 
ATOM   3233 C CG  . PHE A 1 434 ? 118.587 111.990 124.165 1.00 24.47  ? 434 PHE A CG  1 
ATOM   3234 C CD1 . PHE A 1 434 ? 119.774 112.646 124.452 1.00 24.47  ? 434 PHE A CD1 1 
ATOM   3235 C CD2 . PHE A 1 434 ? 118.269 110.854 124.889 1.00 24.47  ? 434 PHE A CD2 1 
ATOM   3236 C CE1 . PHE A 1 434 ? 120.622 112.178 125.435 1.00 24.47  ? 434 PHE A CE1 1 
ATOM   3237 C CE2 . PHE A 1 434 ? 119.115 110.383 125.874 1.00 24.47  ? 434 PHE A CE2 1 
ATOM   3238 C CZ  . PHE A 1 434 ? 120.292 111.046 126.147 1.00 24.47  ? 434 PHE A CZ  1 
ATOM   3239 N N   . ILE A 1 435 ? 117.944 115.645 123.172 1.00 24.66  ? 435 ILE A N   1 
ATOM   3240 C CA  . ILE A 1 435 ? 118.679 116.836 123.589 1.00 24.66  ? 435 ILE A CA  1 
ATOM   3241 C C   . ILE A 1 435 ? 117.771 117.787 124.361 1.00 24.66  ? 435 ILE A C   1 
ATOM   3242 O O   . ILE A 1 435 ? 118.174 118.361 125.381 1.00 24.66  ? 435 ILE A O   1 
ATOM   3243 C CB  . ILE A 1 435 ? 119.318 117.515 122.365 1.00 24.66  ? 435 ILE A CB  1 
ATOM   3244 C CG1 . ILE A 1 435 ? 120.393 116.608 121.769 1.00 24.66  ? 435 ILE A CG1 1 
ATOM   3245 C CG2 . ILE A 1 435 ? 119.915 118.852 122.738 1.00 24.66  ? 435 ILE A CG2 1 
ATOM   3246 C CD1 . ILE A 1 435 ? 121.422 116.149 122.770 1.00 24.66  ? 435 ILE A CD1 1 
ATOM   3247 N N   . ALA A 1 436 ? 116.530 117.959 123.897 1.00 29.48  ? 436 ALA A N   1 
ATOM   3248 C CA  . ALA A 1 436 ? 115.582 118.824 124.591 1.00 29.48  ? 436 ALA A CA  1 
ATOM   3249 C C   . ALA A 1 436 ? 115.273 118.303 125.985 1.00 29.48  ? 436 ALA A C   1 
ATOM   3250 O O   . ALA A 1 436 ? 115.186 119.084 126.939 1.00 29.48  ? 436 ALA A O   1 
ATOM   3251 C CB  . ALA A 1 436 ? 114.294 118.955 123.780 1.00 29.48  ? 436 ALA A CB  1 
ATOM   3252 N N   . THR A 1 437 ? 115.093 116.988 126.123 1.00 22.07  ? 437 THR A N   1 
ATOM   3253 C CA  . THR A 1 437 ? 114.815 116.417 127.437 1.00 22.07  ? 437 THR A CA  1 
ATOM   3254 C C   . THR A 1 437 ? 115.979 116.647 128.395 1.00 22.07  ? 437 THR A C   1 
ATOM   3255 O O   . THR A 1 437 ? 115.775 117.071 129.541 1.00 22.07  ? 437 THR A O   1 
ATOM   3256 C CB  . THR A 1 437 ? 114.501 114.926 127.302 1.00 22.07  ? 437 THR A CB  1 
ATOM   3257 O OG1 . THR A 1 437 ? 113.131 114.760 126.917 1.00 22.07  ? 437 THR A OG1 1 
ATOM   3258 C CG2 . THR A 1 437 ? 114.741 114.194 128.614 1.00 22.07  ? 437 THR A CG2 1 
ATOM   3259 N N   . VAL A 1 438 ? 117.211 116.408 127.933 1.00 31.79  ? 438 VAL A N   1 
ATOM   3260 C CA  . VAL A 1 438 ? 118.372 116.597 128.803 1.00 31.79  ? 438 VAL A CA  1 
ATOM   3261 C C   . VAL A 1 438 ? 118.517 118.065 129.197 1.00 31.79  ? 438 VAL A C   1 
ATOM   3262 O O   . VAL A 1 438 ? 118.764 118.390 130.369 1.00 31.79  ? 438 VAL A O   1 
ATOM   3263 C CB  . VAL A 1 438 ? 119.643 116.057 128.122 1.00 31.79  ? 438 VAL A CB  1 
ATOM   3264 C CG1 . VAL A 1 438 ? 120.886 116.732 128.676 1.00 31.79  ? 438 VAL A CG1 1 
ATOM   3265 C CG2 . VAL A 1 438 ? 119.731 114.552 128.295 1.00 31.79  ? 438 VAL A CG2 1 
ATOM   3266 N N   . GLY A 1 439 ? 118.350 118.972 128.231 1.00 27.38  ? 439 GLY A N   1 
ATOM   3267 C CA  . GLY A 1 439 ? 118.477 120.389 128.530 1.00 27.38  ? 439 GLY A CA  1 
ATOM   3268 C C   . GLY A 1 439 ? 117.400 120.894 129.470 1.00 27.38  ? 439 GLY A C   1 
ATOM   3269 O O   . GLY A 1 439 ? 117.665 121.729 130.340 1.00 27.38  ? 439 GLY A O   1 
ATOM   3270 N N   . LEU A 1 440 ? 116.170 120.404 129.306 1.00 31.77  ? 440 LEU A N   1 
ATOM   3271 C CA  . LEU A 1 440 ? 115.099 120.765 130.227 1.00 31.77  ? 440 LEU A CA  1 
ATOM   3272 C C   . LEU A 1 440 ? 115.372 120.223 131.622 1.00 31.77  ? 440 LEU A C   1 
ATOM   3273 O O   . LEU A 1 440 ? 115.032 120.866 132.622 1.00 31.77  ? 440 LEU A O   1 
ATOM   3274 C CB  . LEU A 1 440 ? 113.762 120.245 129.701 1.00 31.77  ? 440 LEU A CB  1 
ATOM   3275 C CG  . LEU A 1 440 ? 113.082 121.102 128.635 1.00 31.77  ? 440 LEU A CG  1 
ATOM   3276 C CD1 . LEU A 1 440 ? 111.946 120.332 127.989 1.00 31.77  ? 440 LEU A CD1 1 
ATOM   3277 C CD2 . LEU A 1 440 ? 112.585 122.405 129.234 1.00 31.77  ? 440 LEU A CD2 1 
ATOM   3278 N N   . SER A 1 441 ? 115.975 119.035 131.708 1.00 34.82  ? 441 SER A N   1 
ATOM   3279 C CA  . SER A 1 441 ? 116.335 118.475 133.006 1.00 34.82  ? 441 SER A CA  1 
ATOM   3280 C C   . SER A 1 441 ? 117.362 119.348 133.718 1.00 34.82  ? 441 SER A C   1 
ATOM   3281 O O   . SER A 1 441 ? 117.126 119.825 134.833 1.00 34.82  ? 441 SER A O   1 
ATOM   3282 C CB  . SER A 1 441 ? 116.869 117.055 132.832 1.00 34.82  ? 441 SER A CB  1 
ATOM   3283 O OG  . SER A 1 441 ? 117.521 116.611 134.010 1.00 34.82  ? 441 SER A OG  1 
ATOM   3284 N N   . ALA A 1 442 ? 118.515 119.570 133.085 1.00 34.27  ? 442 ALA A N   1 
ATOM   3285 C CA  . ALA A 1 442 ? 119.616 120.281 133.739 1.00 34.27  ? 442 ALA A CA  1 
ATOM   3286 C C   . ALA A 1 442 ? 119.544 121.766 133.392 1.00 34.27  ? 442 ALA A C   1 
ATOM   3287 O O   . ALA A 1 442 ? 120.268 122.276 132.536 1.00 34.27  ? 442 ALA A O   1 
ATOM   3288 C CB  . ALA A 1 442 ? 120.956 119.676 133.341 1.00 34.27  ? 442 ALA A CB  1 
ATOM   3289 N N   . ALA A 1 443 ? 118.652 122.475 134.084 1.00 37.77  ? 443 ALA A N   1 
ATOM   3290 C CA  . ALA A 1 443 ? 118.472 123.894 133.802 1.00 37.77  ? 443 ALA A CA  1 
ATOM   3291 C C   . ALA A 1 443 ? 118.432 124.759 135.058 1.00 37.77  ? 443 ALA A C   1 
ATOM   3292 O O   . ALA A 1 443 ? 118.914 125.896 135.040 1.00 37.77  ? 443 ALA A O   1 
ATOM   3293 C CB  . ALA A 1 443 ? 117.197 124.105 132.986 1.00 37.77  ? 443 ALA A CB  1 
ATOM   3294 N N   . LYS A 1 444 ? 117.850 124.244 136.145 1.00 47.90  ? 444 LYS A N   1 
ATOM   3295 C CA  . LYS A 1 444 ? 117.704 125.049 137.357 1.00 47.90  ? 444 LYS A CA  1 
ATOM   3296 C C   . LYS A 1 444 ? 119.054 125.366 137.992 1.00 47.90  ? 444 LYS A C   1 
ATOM   3297 O O   . LYS A 1 444 ? 119.292 126.500 138.423 1.00 47.90  ? 444 LYS A O   1 
ATOM   3298 C CB  . LYS A 1 444 ? 116.793 124.339 138.359 1.00 47.90  ? 444 LYS A CB  1 
ATOM   3299 C CG  . LYS A 1 444 ? 115.351 124.820 138.336 1.00 47.90  ? 444 LYS A CG  1 
ATOM   3300 C CD  . LYS A 1 444 ? 115.263 126.295 138.696 1.00 47.90  ? 444 LYS A CD  1 
ATOM   3301 C CE  . LYS A 1 444 ? 113.856 126.684 139.115 1.00 47.90  ? 444 LYS A CE  1 
ATOM   3302 N NZ  . LYS A 1 444 ? 113.741 128.145 139.374 1.00 47.90  ? 444 LYS A NZ  1 
ATOM   3303 N N   . THR A 1 445 ? 119.948 124.384 138.053 1.00 53.38  ? 445 THR A N   1 
ATOM   3304 C CA  . THR A 1 445 ? 121.268 124.553 138.645 1.00 53.38  ? 445 THR A CA  1 
ATOM   3305 C C   . THR A 1 445 ? 122.326 124.955 137.622 1.00 53.38  ? 445 THR A C   1 
ATOM   3306 O O   . THR A 1 445 ? 123.520 124.945 137.943 1.00 53.38  ? 445 THR A O   1 
ATOM   3307 C CB  . THR A 1 445 ? 121.683 123.269 139.366 1.00 53.38  ? 445 THR A CB  1 
ATOM   3308 O OG1 . THR A 1 445 ? 121.710 122.184 138.435 1.00 53.38  ? 445 THR A OG1 1 
ATOM   3309 C CG2 . THR A 1 445 ? 120.698 122.943 140.477 1.00 53.38  ? 445 THR A CG2 1 
ATOM   3310 N N   . PHE A 1 446 ? 121.906 125.306 136.404 1.00 55.86  ? 446 PHE A N   1 
ATOM   3311 C CA  . PHE A 1 446 ? 122.837 125.738 135.365 1.00 55.86  ? 446 PHE A CA  1 
ATOM   3312 C C   . PHE A 1 446 ? 123.619 126.976 135.787 1.00 55.86  ? 446 PHE A C   1 
ATOM   3313 O O   . PHE A 1 446 ? 124.851 127.016 135.675 1.00 55.86  ? 446 PHE A O   1 
ATOM   3314 C CB  . PHE A 1 446 ? 122.063 126.004 134.075 1.00 55.86  ? 446 PHE A CB  1 
ATOM   3315 C CG  . PHE A 1 446 ? 122.801 126.851 133.083 1.00 55.86  ? 446 PHE A CG  1 
ATOM   3316 C CD1 . PHE A 1 446 ? 123.940 126.387 132.454 1.00 55.86  ? 446 PHE A CD1 1 
ATOM   3317 C CD2 . PHE A 1 446 ? 122.348 128.126 132.784 1.00 55.86  ? 446 PHE A CD2 1 
ATOM   3318 C CE1 . PHE A 1 446 ? 124.609 127.180 131.543 1.00 55.86  ? 446 PHE A CE1 1 
ATOM   3319 C CE2 . PHE A 1 446 ? 123.013 128.919 131.876 1.00 55.86  ? 446 PHE A CE2 1 
ATOM   3320 C CZ  . PHE A 1 446 ? 124.146 128.445 131.254 1.00 55.86  ? 446 PHE A CZ  1 
ATOM   3321 N N   . ILE A 1 447 ? 122.916 128.003 136.269 1.00 63.76  ? 447 ILE A N   1 
ATOM   3322 C CA  . ILE A 1 447 ? 123.597 129.233 136.657 1.00 63.76  ? 447 ILE A CA  1 
ATOM   3323 C C   . ILE A 1 447 ? 124.462 129.012 137.894 1.00 63.76  ? 447 ILE A C   1 
ATOM   3324 O O   . ILE A 1 447 ? 125.547 129.593 138.006 1.00 63.76  ? 447 ILE A O   1 
ATOM   3325 C CB  . ILE A 1 447 ? 122.578 130.377 136.841 1.00 63.76  ? 447 ILE A CB  1 
ATOM   3326 C CG1 . ILE A 1 447 ? 123.289 131.733 136.834 1.00 63.76  ? 447 ILE A CG1 1 
ATOM   3327 C CG2 . ILE A 1 447 ? 121.727 130.186 138.092 1.00 63.76  ? 447 ILE A CG2 1 
ATOM   3328 C CD1 . ILE A 1 447 ? 122.427 132.883 137.318 1.00 63.76  ? 447 ILE A CD1 1 
ATOM   3329 N N   . SER A 1 448 ? 124.027 128.156 138.823 1.00 66.06  ? 448 SER A N   1 
ATOM   3330 C CA  . SER A 1 448 ? 124.850 127.860 139.991 1.00 66.06  ? 448 SER A CA  1 
ATOM   3331 C C   . SER A 1 448 ? 126.138 127.153 139.593 1.00 66.06  ? 448 SER A C   1 
ATOM   3332 O O   . SER A 1 448 ? 127.215 127.470 140.114 1.00 66.06  ? 448 SER A O   1 
ATOM   3333 C CB  . SER A 1 448 ? 124.064 127.016 140.992 1.00 66.06  ? 448 SER A CB  1 
ATOM   3334 O OG  . SER A 1 448 ? 124.924 126.123 141.679 1.00 66.06  ? 448 SER A OG  1 
ATOM   3335 N N   . ALA A 1 449 ? 126.058 126.209 138.655 1.00 66.75  ? 449 ALA A N   1 
ATOM   3336 C CA  . ALA A 1 449 ? 127.267 125.525 138.222 1.00 66.75  ? 449 ALA A CA  1 
ATOM   3337 C C   . ALA A 1 449 ? 128.166 126.406 137.365 1.00 66.75  ? 449 ALA A C   1 
ATOM   3338 O O   . ALA A 1 449 ? 129.390 126.253 137.419 1.00 66.75  ? 449 ALA A O   1 
ATOM   3339 C CB  . ALA A 1 449 ? 126.913 124.252 137.458 1.00 66.75  ? 449 ALA A CB  1 
ATOM   3340 N N   . ILE A 1 450 ? 127.599 127.345 136.606 1.00 67.35  ? 450 ILE A N   1 
ATOM   3341 C CA  . ILE A 1 450 ? 128.436 128.274 135.854 1.00 67.35  ? 450 ILE A CA  1 
ATOM   3342 C C   . ILE A 1 450 ? 129.032 129.348 136.752 1.00 67.35  ? 450 ILE A C   1 
ATOM   3343 O O   . ILE A 1 450 ? 130.029 129.976 136.376 1.00 67.35  ? 450 ILE A O   1 
ATOM   3344 C CB  . ILE A 1 450 ? 127.656 128.911 134.690 1.00 67.35  ? 450 ILE A CB  1 
ATOM   3345 C CG1 . ILE A 1 450 ? 128.587 129.181 133.508 1.00 67.35  ? 450 ILE A CG1 1 
ATOM   3346 C CG2 . ILE A 1 450 ? 126.974 130.202 135.122 1.00 67.35  ? 450 ILE A CG2 1 
ATOM   3347 C CD1 . ILE A 1 450 ? 129.345 127.970 133.035 1.00 67.35  ? 450 ILE A CD1 1 
ATOM   3348 N N   . GLN A 1 451 ? 128.452 129.580 137.932 1.00 71.28  ? 451 GLN A N   1 
ATOM   3349 C CA  . GLN A 1 451 ? 129.137 130.390 138.932 1.00 71.28  ? 451 GLN A CA  1 
ATOM   3350 C C   . GLN A 1 451 ? 130.254 129.605 139.606 1.00 71.28  ? 451 GLN A C   1 
ATOM   3351 O O   . GLN A 1 451 ? 131.334 130.152 139.857 1.00 71.28  ? 451 GLN A O   1 
ATOM   3352 C CB  . GLN A 1 451 ? 128.152 130.907 139.982 1.00 71.28  ? 451 GLN A CB  1 
ATOM   3353 C CG  . GLN A 1 451 ? 127.145 131.910 139.458 1.00 71.28  ? 451 GLN A CG  1 
ATOM   3354 C CD  . GLN A 1 451 ? 127.750 133.283 139.256 1.00 71.28  ? 451 GLN A CD  1 
ATOM   3355 O OE1 . GLN A 1 451 ? 128.678 133.674 139.963 1.00 71.28  ? 451 GLN A OE1 1 
ATOM   3356 N NE2 . GLN A 1 451 ? 127.227 134.023 138.285 1.00 71.28  ? 451 GLN A NE2 1 
ATOM   3357 N N   . SER A 1 452 ? 130.013 128.327 139.911 1.00 71.63  ? 452 SER A N   1 
ATOM   3358 C CA  . SER A 1 452 ? 131.017 127.533 140.613 1.00 71.63  ? 452 SER A CA  1 
ATOM   3359 C C   . SER A 1 452 ? 132.245 127.294 139.741 1.00 71.63  ? 452 SER A C   1 
ATOM   3360 O O   . SER A 1 452 ? 133.380 127.532 140.168 1.00 71.63  ? 452 SER A O   1 
ATOM   3361 C CB  . SER A 1 452 ? 130.417 126.206 141.081 1.00 71.63  ? 452 SER A CB  1 
ATOM   3362 O OG  . SER A 1 452 ? 129.886 125.468 140.000 1.00 71.63  ? 452 SER A OG  1 
ATOM   3363 N N   . MET A 1 453 ? 132.043 126.819 138.505 1.00 73.69  ? 453 MET A N   1 
ATOM   3364 C CA  . MET A 1 453 ? 133.159 126.487 137.607 1.00 73.69  ? 453 MET A CA  1 
ATOM   3365 C C   . MET A 1 453 ? 132.951 127.199 136.271 1.00 73.69  ? 453 MET A C   1 
ATOM   3366 O O   . MET A 1 453 ? 132.332 126.658 135.353 1.00 73.69  ? 453 MET A O   1 
ATOM   3367 C CB  . MET A 1 453 ? 133.295 124.971 137.431 1.00 73.69  ? 453 MET A CB  1 
ATOM   3368 C CG  . MET A 1 453 ? 132.008 124.190 137.610 1.00 73.69  ? 453 MET A CG  1 
ATOM   3369 S SD  . MET A 1 453 ? 132.291 122.411 137.567 1.00 73.69  ? 453 MET A SD  1 
ATOM   3370 C CE  . MET A 1 453 ? 130.608 121.816 137.659 1.00 73.69  ? 453 MET A CE  1 
ATOM   3371 N N   . GLY A 1 454 ? 133.480 128.417 136.171 1.00 70.23  ? 454 GLY A N   1 
ATOM   3372 C CA  . GLY A 1 454 ? 133.316 129.231 134.983 1.00 70.23  ? 454 GLY A CA  1 
ATOM   3373 C C   . GLY A 1 454 ? 134.156 128.836 133.784 1.00 70.23  ? 454 GLY A C   1 
ATOM   3374 O O   . GLY A 1 454 ? 133.615 128.448 132.744 1.00 70.23  ? 454 GLY A O   1 
ATOM   3375 N N   . ILE A 1 455 ? 135.481 128.916 133.916 1.00 67.74  ? 455 ILE A N   1 
ATOM   3376 C CA  . ILE A 1 455 ? 136.383 128.794 132.778 1.00 67.74  ? 455 ILE A CA  1 
ATOM   3377 C C   . ILE A 1 455 ? 137.065 127.425 132.732 1.00 67.74  ? 455 ILE A C   1 
ATOM   3378 O O   . ILE A 1 455 ? 137.533 127.002 131.667 1.00 67.74  ? 455 ILE A O   1 
ATOM   3379 C CB  . ILE A 1 455 ? 137.396 129.958 132.803 1.00 67.74  ? 455 ILE A CB  1 
ATOM   3380 C CG1 . ILE A 1 455 ? 136.683 131.255 132.424 1.00 67.74  ? 455 ILE A CG1 1 
ATOM   3381 C CG2 . ILE A 1 455 ? 138.587 129.754 131.869 1.00 67.74  ? 455 ILE A CG2 1 
ATOM   3382 C CD1 . ILE A 1 455 ? 135.943 131.185 131.090 1.00 67.74  ? 455 ILE A CD1 1 
ATOM   3383 N N   . SER A 1 456 ? 137.009 126.664 133.824 1.00 65.39  ? 456 SER A N   1 
ATOM   3384 C CA  . SER A 1 456 ? 137.692 125.381 133.900 1.00 65.39  ? 456 SER A CA  1 
ATOM   3385 C C   . SER A 1 456 ? 136.828 124.233 133.389 1.00 65.39  ? 456 SER A C   1 
ATOM   3386 O O   . SER A 1 456 ? 137.157 123.065 133.622 1.00 65.39  ? 456 SER A O   1 
ATOM   3387 C CB  . SER A 1 456 ? 138.136 125.109 135.337 1.00 65.39  ? 456 SER A CB  1 
ATOM   3388 O OG  . SER A 1 456 ? 138.419 123.734 135.536 1.00 65.39  ? 456 SER A OG  1 
ATOM   3389 N N   . VAL A 1 457 ? 135.737 124.537 132.684 1.00 59.71  ? 457 VAL A N   1 
ATOM   3390 C CA  . VAL A 1 457 ? 134.866 123.499 132.144 1.00 59.71  ? 457 VAL A CA  1 
ATOM   3391 C C   . VAL A 1 457 ? 134.579 123.794 130.674 1.00 59.71  ? 457 VAL A C   1 
ATOM   3392 O O   . VAL A 1 457 ? 134.079 122.933 129.940 1.00 59.71  ? 457 VAL A O   1 
ATOM   3393 C CB  . VAL A 1 457 ? 133.575 123.389 132.982 1.00 59.71  ? 457 VAL A CB  1 
ATOM   3394 C CG1 . VAL A 1 457 ? 132.719 124.632 132.833 1.00 59.71  ? 457 VAL A CG1 1 
ATOM   3395 C CG2 . VAL A 1 457 ? 132.797 122.120 132.655 1.00 59.71  ? 457 VAL A CG2 1 
ATOM   3396 N N   . LEU A 1 458 ? 134.919 125.000 130.222 1.00 53.51  ? 458 LEU A N   1 
ATOM   3397 C CA  . LEU A 1 458 ? 134.767 125.365 128.816 1.00 53.51  ? 458 LEU A CA  1 
ATOM   3398 C C   . LEU A 1 458 ? 136.070 125.293 128.034 1.00 53.51  ? 458 LEU A C   1 
ATOM   3399 O O   . LEU A 1 458 ? 136.079 124.786 126.908 1.00 53.51  ? 458 LEU A O   1 
ATOM   3400 C CB  . LEU A 1 458 ? 134.181 126.775 128.676 1.00 53.51  ? 458 LEU A CB  1 
ATOM   3401 C CG  . LEU A 1 458 ? 133.206 127.330 129.710 1.00 53.51  ? 458 LEU A CG  1 
ATOM   3402 C CD1 . LEU A 1 458 ? 132.771 128.723 129.298 1.00 53.51  ? 458 LEU A CD1 1 
ATOM   3403 C CD2 . LEU A 1 458 ? 131.995 126.428 129.797 1.00 53.51  ? 458 LEU A CD2 1 
ATOM   3404 N N   . LEU A 1 459 ? 137.170 125.796 128.598 1.00 53.26  ? 459 LEU A N   1 
ATOM   3405 C CA  . LEU A 1 459 ? 138.449 125.739 127.898 1.00 53.26  ? 459 LEU A CA  1 
ATOM   3406 C C   . LEU A 1 459 ? 138.931 124.303 127.743 1.00 53.26  ? 459 LEU A C   1 
ATOM   3407 O O   . LEU A 1 459 ? 139.491 123.940 126.703 1.00 53.26  ? 459 LEU A O   1 
ATOM   3408 C CB  . LEU A 1 459 ? 139.491 126.583 128.632 1.00 53.26  ? 459 LEU A CB  1 
ATOM   3409 C CG  . LEU A 1 459 ? 139.319 128.103 128.565 1.00 53.26  ? 459 LEU A CG  1 
ATOM   3410 C CD1 . LEU A 1 459 ? 140.645 128.795 128.822 1.00 53.26  ? 459 LEU A CD1 1 
ATOM   3411 C CD2 . LEU A 1 459 ? 138.752 128.527 127.221 1.00 53.26  ? 459 LEU A CD2 1 
ATOM   3412 N N   . ILE A 1 460 ? 138.727 123.474 128.769 1.00 50.84  ? 460 ILE A N   1 
ATOM   3413 C CA  . ILE A 1 460 ? 139.098 122.064 128.677 1.00 50.84  ? 460 ILE A CA  1 
ATOM   3414 C C   . ILE A 1 460 ? 138.292 121.375 127.584 1.00 50.84  ? 460 ILE A C   1 
ATOM   3415 O O   . ILE A 1 460 ? 138.833 120.593 126.790 1.00 50.84  ? 460 ILE A O   1 
ATOM   3416 C CB  . ILE A 1 460 ? 138.910 121.376 130.042 1.00 50.84  ? 460 ILE A CB  1 
ATOM   3417 C CG1 . ILE A 1 460 ? 139.898 121.946 131.057 1.00 50.84  ? 460 ILE A CG1 1 
ATOM   3418 C CG2 . ILE A 1 460 ? 139.091 119.875 129.918 1.00 50.84  ? 460 ILE A CG2 1 
ATOM   3419 C CD1 . ILE A 1 460 ? 141.317 121.975 130.558 1.00 50.84  ? 460 ILE A CD1 1 
ATOM   3420 N N   . GLY A 1 461 ? 136.989 121.656 127.525 1.00 46.79  ? 461 GLY A N   1 
ATOM   3421 C CA  . GLY A 1 461 ? 136.166 121.095 126.467 1.00 46.79  ? 461 GLY A CA  1 
ATOM   3422 C C   . GLY A 1 461 ? 136.601 121.548 125.087 1.00 46.79  ? 461 GLY A C   1 
ATOM   3423 O O   . GLY A 1 461 ? 136.647 120.751 124.149 1.00 46.79  ? 461 GLY A O   1 
ATOM   3424 N N   . ALA A 1 462 ? 136.937 122.833 124.947 1.00 47.31  ? 462 ALA A N   1 
ATOM   3425 C CA  . ALA A 1 462 ? 137.398 123.343 123.660 1.00 47.31  ? 462 ALA A CA  1 
ATOM   3426 C C   . ALA A 1 462 ? 138.707 122.687 123.237 1.00 47.31  ? 462 ALA A C   1 
ATOM   3427 O O   . ALA A 1 462 ? 138.877 122.319 122.067 1.00 47.31  ? 462 ALA A O   1 
ATOM   3428 C CB  . ALA A 1 462 ? 137.556 124.861 123.725 1.00 47.31  ? 462 ALA A CB  1 
ATOM   3429 N N   . VAL A 1 463 ? 139.644 122.533 124.176 1.00 43.02  ? 463 VAL A N   1 
ATOM   3430 C CA  . VAL A 1 463 ? 140.924 121.903 123.861 1.00 43.02  ? 463 VAL A CA  1 
ATOM   3431 C C   . VAL A 1 463 ? 140.717 120.449 123.456 1.00 43.02  ? 463 VAL A C   1 
ATOM   3432 O O   . VAL A 1 463 ? 141.263 119.983 122.450 1.00 43.02  ? 463 VAL A O   1 
ATOM   3433 C CB  . VAL A 1 463 ? 141.893 122.028 125.051 1.00 43.02  ? 463 VAL A CB  1 
ATOM   3434 C CG1 . VAL A 1 463 ? 143.100 121.129 124.853 1.00 43.02  ? 463 VAL A CG1 1 
ATOM   3435 C CG2 . VAL A 1 463 ? 142.338 123.471 125.214 1.00 43.02  ? 463 VAL A CG2 1 
ATOM   3436 N N   . ILE A 1 464 ? 139.907 119.714 124.223 1.00 41.32  ? 464 ILE A N   1 
ATOM   3437 C CA  . ILE A 1 464 ? 139.663 118.313 123.903 1.00 41.32  ? 464 ILE A CA  1 
ATOM   3438 C C   . ILE A 1 464 ? 138.834 118.146 122.638 1.00 41.32  ? 464 ILE A C   1 
ATOM   3439 O O   . ILE A 1 464 ? 138.853 117.072 122.028 1.00 41.32  ? 464 ILE A O   1 
ATOM   3440 C CB  . ILE A 1 464 ? 139.007 117.595 125.098 1.00 41.32  ? 464 ILE A CB  1 
ATOM   3441 C CG1 . ILE A 1 464 ? 139.396 116.122 125.081 1.00 41.32  ? 464 ILE A CG1 1 
ATOM   3442 C CG2 . ILE A 1 464 ? 137.496 117.744 125.071 1.00 41.32  ? 464 ILE A CG2 1 
ATOM   3443 C CD1 . ILE A 1 464 ? 140.868 115.919 125.170 1.00 41.32  ? 464 ILE A CD1 1 
ATOM   3444 N N   . SER A 1 465 ? 138.106 119.179 122.221 1.00 42.94  ? 465 SER A N   1 
ATOM   3445 C CA  . SER A 1 465 ? 137.323 119.104 120.998 1.00 42.94  ? 465 SER A CA  1 
ATOM   3446 C C   . SER A 1 465 ? 138.115 119.502 119.762 1.00 42.94  ? 465 SER A C   1 
ATOM   3447 O O   . SER A 1 465 ? 137.812 119.023 118.664 1.00 42.94  ? 465 SER A O   1 
ATOM   3448 C CB  . SER A 1 465 ? 136.082 119.990 121.126 1.00 42.94  ? 465 SER A CB  1 
ATOM   3449 O OG  . SER A 1 465 ? 135.455 120.177 119.873 1.00 42.94  ? 465 SER A OG  1 
ATOM   3450 N N   . ILE A 1 466 ? 139.115 120.365 119.910 1.00 41.09  ? 466 ILE A N   1 
ATOM   3451 C CA  . ILE A 1 466 ? 139.865 120.894 118.773 1.00 41.09  ? 466 ILE A CA  1 
ATOM   3452 C C   . ILE A 1 466 ? 141.181 120.155 118.561 1.00 41.09  ? 466 ILE A C   1 
ATOM   3453 O O   . ILE A 1 466 ? 141.500 119.758 117.440 1.00 41.09  ? 466 ILE A O   1 
ATOM   3454 C CB  . ILE A 1 466 ? 140.095 122.412 118.953 1.00 41.09  ? 466 ILE A CB  1 
ATOM   3455 C CG1 . ILE A 1 466 ? 138.795 123.177 118.701 1.00 41.09  ? 466 ILE A CG1 1 
ATOM   3456 C CG2 . ILE A 1 466 ? 141.205 122.904 118.037 1.00 41.09  ? 466 ILE A CG2 1 
ATOM   3457 C CD1 . ILE A 1 466 ? 138.419 123.279 117.240 1.00 41.09  ? 466 ILE A CD1 1 
ATOM   3458 N N   . LEU A 1 467 ? 141.959 119.961 119.630 1.00 40.43  ? 467 LEU A N   1 
ATOM   3459 C CA  . LEU A 1 467 ? 143.345 119.514 119.487 1.00 40.43  ? 467 LEU A CA  1 
ATOM   3460 C C   . LEU A 1 467 ? 143.513 118.158 118.801 1.00 40.43  ? 467 LEU A C   1 
ATOM   3461 O O   . LEU A 1 467 ? 144.395 118.050 117.932 1.00 40.43  ? 467 LEU A O   1 
ATOM   3462 C CB  . LEU A 1 467 ? 144.032 119.529 120.857 1.00 40.43  ? 467 LEU A CB  1 
ATOM   3463 C CG  . LEU A 1 467 ? 145.481 119.038 120.875 1.00 40.43  ? 467 LEU A CG  1 
ATOM   3464 C CD1 . LEU A 1 467 ? 146.352 119.912 119.992 1.00 40.43  ? 467 LEU A CD1 1 
ATOM   3465 C CD2 . LEU A 1 467 ? 146.026 119.009 122.291 1.00 40.43  ? 467 LEU A CD2 1 
ATOM   3466 N N   . PRO A 1 468 ? 142.760 117.095 119.138 1.00 38.06  ? 468 PRO A N   1 
ATOM   3467 C CA  . PRO A 1 468 ? 142.979 115.818 118.428 1.00 38.06  ? 468 PRO A CA  1 
ATOM   3468 C C   . PRO A 1 468 ? 142.759 115.902 116.927 1.00 38.06  ? 468 PRO A C   1 
ATOM   3469 O O   . PRO A 1 468 ? 143.473 115.237 116.161 1.00 38.06  ? 468 PRO A O   1 
ATOM   3470 C CB  . PRO A 1 468 ? 141.971 114.875 119.097 1.00 38.06  ? 468 PRO A CB  1 
ATOM   3471 C CG  . PRO A 1 468 ? 141.773 115.444 120.442 1.00 38.06  ? 468 PRO A CG  1 
ATOM   3472 C CD  . PRO A 1 468 ? 141.792 116.924 120.238 1.00 38.06  ? 468 PRO A CD  1 
ATOM   3473 N N   . HIS A 1 469 ? 141.791 116.709 116.486 1.00 39.05  ? 469 HIS A N   1 
ATOM   3474 C CA  . HIS A 1 469 ? 141.565 116.884 115.056 1.00 39.05  ? 469 HIS A CA  1 
ATOM   3475 C C   . HIS A 1 469 ? 142.784 117.494 114.376 1.00 39.05  ? 469 HIS A C   1 
ATOM   3476 O O   . HIS A 1 469 ? 143.191 117.041 113.301 1.00 39.05  ? 469 HIS A O   1 
ATOM   3477 C CB  . HIS A 1 469 ? 140.330 117.752 114.820 1.00 39.05  ? 469 HIS A CB  1 
ATOM   3478 C CG  . HIS A 1 469 ? 139.040 117.071 115.154 1.00 39.05  ? 469 HIS A CG  1 
ATOM   3479 N ND1 . HIS A 1 469 ? 138.555 116.001 114.433 1.00 39.05  ? 469 HIS A ND1 1 
ATOM   3480 C CD2 . HIS A 1 469 ? 138.134 117.306 116.133 1.00 39.05  ? 469 HIS A CD2 1 
ATOM   3481 C CE1 . HIS A 1 469 ? 137.405 115.608 114.952 1.00 39.05  ? 469 HIS A CE1 1 
ATOM   3482 N NE2 . HIS A 1 469 ? 137.128 116.383 115.985 1.00 39.05  ? 469 HIS A NE2 1 
ATOM   3483 N N   . ILE A 1 470 ? 143.388 118.511 114.997 1.00 39.85  ? 470 ILE A N   1 
ATOM   3484 C CA  . ILE A 1 470 ? 144.568 119.152 114.420 1.00 39.85  ? 470 ILE A CA  1 
ATOM   3485 C C   . ILE A 1 470 ? 145.726 118.165 114.333 1.00 39.85  ? 470 ILE A C   1 
ATOM   3486 O O   . ILE A 1 470 ? 146.421 118.088 113.311 1.00 39.85  ? 470 ILE A O   1 
ATOM   3487 C CB  . ILE A 1 470 ? 144.952 120.399 115.239 1.00 39.85  ? 470 ILE A CB  1 
ATOM   3488 C CG1 . ILE A 1 470 ? 143.883 121.483 115.098 1.00 39.85  ? 470 ILE A CG1 1 
ATOM   3489 C CG2 . ILE A 1 470 ? 146.306 120.932 114.802 1.00 39.85  ? 470 ILE A CG2 1 
ATOM   3490 C CD1 . ILE A 1 470 ? 144.261 122.805 115.730 1.00 39.85  ? 470 ILE A CD1 1 
ATOM   3491 N N   . ILE A 1 471 ? 145.947 117.395 115.402 1.00 41.37  ? 471 ILE A N   1 
ATOM   3492 C CA  . ILE A 1 471 ? 147.053 116.441 115.429 1.00 41.37  ? 471 ILE A CA  1 
ATOM   3493 C C   . ILE A 1 471 ? 146.879 115.390 114.341 1.00 41.37  ? 471 ILE A C   1 
ATOM   3494 O O   . ILE A 1 471 ? 147.809 115.100 113.576 1.00 41.37  ? 471 ILE A O   1 
ATOM   3495 C CB  . ILE A 1 471 ? 147.165 115.793 116.821 1.00 41.37  ? 471 ILE A CB  1 
ATOM   3496 C CG1 . ILE A 1 471 ? 147.498 116.847 117.877 1.00 41.37  ? 471 ILE A CG1 1 
ATOM   3497 C CG2 . ILE A 1 471 ? 148.208 114.686 116.815 1.00 41.37  ? 471 ILE A CG2 1 
ATOM   3498 C CD1 . ILE A 1 471 ? 147.711 116.277 119.261 1.00 41.37  ? 471 ILE A CD1 1 
ATOM   3499 N N   . THR A 1 472 ? 145.678 114.812 114.245 1.00 45.60  ? 472 THR A N   1 
ATOM   3500 C CA  . THR A 1 472 ? 145.468 113.764 113.253 1.00 45.60  ? 472 THR A CA  1 
ATOM   3501 C C   . THR A 1 472 ? 145.476 114.319 111.831 1.00 45.60  ? 472 THR A C   1 
ATOM   3502 O O   . THR A 1 472 ? 145.942 113.636 110.913 1.00 45.60  ? 472 THR A O   1 
ATOM   3503 C CB  . THR A 1 472 ? 144.181 112.989 113.567 1.00 45.60  ? 472 THR A CB  1 
ATOM   3504 O OG1 . THR A 1 472 ? 144.279 111.659 113.041 1.00 45.60  ? 472 THR A OG1 1 
ATOM   3505 C CG2 . THR A 1 472 ? 142.941 113.670 113.016 1.00 45.60  ? 472 THR A CG2 1 
ATOM   3506 N N   . PHE A 1 473 ? 145.029 115.564 111.632 1.00 47.36  ? 473 PHE A N   1 
ATOM   3507 C CA  . PHE A 1 473 ? 145.087 116.173 110.308 1.00 47.36  ? 473 PHE A CA  1 
ATOM   3508 C C   . PHE A 1 473 ? 146.537 116.387 109.893 1.00 47.36  ? 473 PHE A C   1 
ATOM   3509 O O   . PHE A 1 473 ? 146.920 116.077 108.759 1.00 47.36  ? 473 PHE A O   1 
ATOM   3510 C CB  . PHE A 1 473 ? 144.296 117.490 110.323 1.00 47.36  ? 473 PHE A CB  1 
ATOM   3511 C CG  . PHE A 1 473 ? 144.818 118.567 109.394 1.00 47.36  ? 473 PHE A CG  1 
ATOM   3512 C CD1 . PHE A 1 473 ? 144.997 118.336 108.034 1.00 47.36  ? 473 PHE A CD1 1 
ATOM   3513 C CD2 . PHE A 1 473 ? 145.143 119.815 109.897 1.00 47.36  ? 473 PHE A CD2 1 
ATOM   3514 C CE1 . PHE A 1 473 ? 145.478 119.330 107.204 1.00 47.36  ? 473 PHE A CE1 1 
ATOM   3515 C CE2 . PHE A 1 473 ? 145.625 120.810 109.071 1.00 47.36  ? 473 PHE A CE2 1 
ATOM   3516 C CZ  . PHE A 1 473 ? 145.792 120.568 107.723 1.00 47.36  ? 473 PHE A CZ  1 
ATOM   3517 N N   . VAL A 1 474 ? 147.361 116.903 110.809 1.00 48.56  ? 474 VAL A N   1 
ATOM   3518 C CA  . VAL A 1 474 ? 148.771 117.132 110.504 1.00 48.56  ? 474 VAL A CA  1 
ATOM   3519 C C   . VAL A 1 474 ? 149.462 115.813 110.179 1.00 48.56  ? 474 VAL A C   1 
ATOM   3520 O O   . VAL A 1 474 ? 150.175 115.697 109.173 1.00 48.56  ? 474 VAL A O   1 
ATOM   3521 C CB  . VAL A 1 474 ? 149.457 117.864 111.672 1.00 48.56  ? 474 VAL A CB  1 
ATOM   3522 C CG1 . VAL A 1 474 ? 150.957 117.614 111.663 1.00 48.56  ? 474 VAL A CG1 1 
ATOM   3523 C CG2 . VAL A 1 474 ? 149.165 119.354 111.605 1.00 48.56  ? 474 VAL A CG2 1 
ATOM   3524 N N   . ILE A 1 475 ? 149.226 114.789 111.005 1.00 50.10  ? 475 ILE A N   1 
ATOM   3525 C CA  . ILE A 1 475 ? 149.879 113.498 110.801 1.00 50.10  ? 475 ILE A CA  1 
ATOM   3526 C C   . ILE A 1 475 ? 149.448 112.875 109.478 1.00 50.10  ? 475 ILE A C   1 
ATOM   3527 O O   . ILE A 1 475 ? 150.276 112.344 108.728 1.00 50.10  ? 475 ILE A O   1 
ATOM   3528 C CB  . ILE A 1 475 ? 149.595 112.563 111.991 1.00 50.10  ? 475 ILE A CB  1 
ATOM   3529 C CG1 . ILE A 1 475 ? 150.359 113.033 113.229 1.00 50.10  ? 475 ILE A CG1 1 
ATOM   3530 C CG2 . ILE A 1 475 ? 149.976 111.130 111.657 1.00 50.10  ? 475 ILE A CG2 1 
ATOM   3531 C CD1 . ILE A 1 475 ? 150.198 112.122 114.428 1.00 50.10  ? 475 ILE A CD1 1 
ATOM   3532 N N   . CYS A 1 476 ? 148.153 112.941 109.160 1.00 55.99  ? 476 CYS A N   1 
ATOM   3533 C CA  . CYS A 1 476 ? 147.662 112.307 107.942 1.00 55.99  ? 476 CYS A CA  1 
ATOM   3534 C C   . CYS A 1 476 ? 148.119 113.049 106.690 1.00 55.99  ? 476 CYS A C   1 
ATOM   3535 O O   . CYS A 1 476 ? 148.528 112.419 105.708 1.00 55.99  ? 476 CYS A O   1 
ATOM   3536 C CB  . CYS A 1 476 ? 146.137 112.212 107.982 1.00 55.99  ? 476 CYS A CB  1 
ATOM   3537 N N   . TYR A 1 477 ? 148.060 114.383 106.699 1.00 60.14  ? 477 TYR A N   1 
ATOM   3538 C CA  . TYR A 1 477 ? 148.292 115.132 105.470 1.00 60.14  ? 477 TYR A CA  1 
ATOM   3539 C C   . TYR A 1 477 ? 149.774 115.400 105.226 1.00 60.14  ? 477 TYR A C   1 
ATOM   3540 O O   . TYR A 1 477 ? 150.250 115.251 104.096 1.00 60.14  ? 477 TYR A O   1 
ATOM   3541 C CB  . TYR A 1 477 ? 147.513 116.447 105.506 1.00 60.14  ? 477 TYR A CB  1 
ATOM   3542 C CG  . TYR A 1 477 ? 147.729 117.329 104.297 1.00 60.14  ? 477 TYR A CG  1 
ATOM   3543 C CD1 . TYR A 1 477 ? 147.511 116.846 103.014 1.00 60.14  ? 477 TYR A CD1 1 
ATOM   3544 C CD2 . TYR A 1 477 ? 148.144 118.645 104.440 1.00 60.14  ? 477 TYR A CD2 1 
ATOM   3545 C CE1 . TYR A 1 477 ? 147.705 117.650 101.907 1.00 60.14  ? 477 TYR A CE1 1 
ATOM   3546 C CE2 . TYR A 1 477 ? 148.341 119.456 103.339 1.00 60.14  ? 477 TYR A CE2 1 
ATOM   3547 C CZ  . TYR A 1 477 ? 148.120 118.953 102.075 1.00 60.14  ? 477 TYR A CZ  1 
ATOM   3548 O OH  . TYR A 1 477 ? 148.315 119.757 100.976 1.00 60.14  ? 477 TYR A OH  1 
ATOM   3549 N N   . TYR A 1 478 ? 150.521 115.794 106.258 1.00 59.83  ? 478 TYR A N   1 
ATOM   3550 C CA  . TYR A 1 478 ? 151.902 116.210 106.043 1.00 59.83  ? 478 TYR A CA  1 
ATOM   3551 C C   . TYR A 1 478 ? 152.886 115.047 106.107 1.00 59.83  ? 478 TYR A C   1 
ATOM   3552 O O   . TYR A 1 478 ? 153.775 114.939 105.258 1.00 59.83  ? 478 TYR A O   1 
ATOM   3553 C CB  . TYR A 1 478 ? 152.294 117.284 107.061 1.00 59.83  ? 478 TYR A CB  1 
ATOM   3554 C CG  . TYR A 1 478 ? 151.595 118.603 106.843 1.00 59.83  ? 478 TYR A CG  1 
ATOM   3555 C CD1 . TYR A 1 478 ? 151.764 119.309 105.662 1.00 59.83  ? 478 TYR A CD1 1 
ATOM   3556 C CD2 . TYR A 1 478 ? 150.771 119.144 107.819 1.00 59.83  ? 478 TYR A CD2 1 
ATOM   3557 C CE1 . TYR A 1 478 ? 151.129 120.516 105.455 1.00 59.83  ? 478 TYR A CE1 1 
ATOM   3558 C CE2 . TYR A 1 478 ? 150.131 120.351 107.622 1.00 59.83  ? 478 TYR A CE2 1 
ATOM   3559 C CZ  . TYR A 1 478 ? 150.313 121.033 106.438 1.00 59.83  ? 478 TYR A CZ  1 
ATOM   3560 O OH  . TYR A 1 478 ? 149.680 122.236 106.236 1.00 59.83  ? 478 TYR A OH  1 
ATOM   3561 N N   . LEU A 1 479 ? 152.750 114.176 107.104 1.00 61.35  ? 479 LEU A N   1 
ATOM   3562 C CA  . LEU A 1 479 ? 153.715 113.099 107.288 1.00 61.35  ? 479 LEU A CA  1 
ATOM   3563 C C   . LEU A 1 479 ? 153.373 111.866 106.459 1.00 61.35  ? 479 LEU A C   1 
ATOM   3564 O O   . LEU A 1 479 ? 154.216 111.370 105.705 1.00 61.35  ? 479 LEU A O   1 
ATOM   3565 C CB  . LEU A 1 479 ? 153.819 112.722 108.771 1.00 61.35  ? 479 LEU A CB  1 
ATOM   3566 C CG  . LEU A 1 479 ? 154.667 113.593 109.708 1.00 61.35  ? 479 LEU A CG  1 
ATOM   3567 C CD1 . LEU A 1 479 ? 154.079 114.985 109.920 1.00 61.35  ? 479 LEU A CD1 1 
ATOM   3568 C CD2 . LEU A 1 479 ? 154.874 112.888 111.042 1.00 61.35  ? 479 LEU A CD2 1 
ATOM   3569 N N   . MET A 1 480 ? 152.147 111.353 106.590 1.00 65.17  ? 480 MET A N   1 
ATOM   3570 C CA  . MET A 1 480 ? 151.781 110.130 105.887 1.00 65.17  ? 480 MET A CA  1 
ATOM   3571 C C   . MET A 1 480 ? 151.352 110.382 104.448 1.00 65.17  ? 480 MET A C   1 
ATOM   3572 O O   . MET A 1 480 ? 151.417 109.455 103.633 1.00 65.17  ? 480 MET A O   1 
ATOM   3573 C CB  . MET A 1 480 ? 150.669 109.397 106.642 1.00 65.17  ? 480 MET A CB  1 
ATOM   3574 C CG  . MET A 1 480 ? 150.866 107.885 106.695 1.00 65.17  ? 480 MET A CG  1 
ATOM   3575 S SD  . MET A 1 480 ? 149.545 107.008 107.551 1.00 65.17  ? 480 MET A SD  1 
ATOM   3576 C CE  . MET A 1 480 ? 148.748 106.166 106.183 1.00 65.17  ? 480 MET A CE  1 
ATOM   3577 N N   . LYS A 1 481 ? 150.924 111.605 104.124 1.00 68.43  ? 481 LYS A N   1 
ATOM   3578 C CA  . LYS A 1 481 ? 150.560 112.009 102.764 1.00 68.43  ? 481 LYS A CA  1 
ATOM   3579 C C   . LYS A 1 481 ? 149.437 111.133 102.202 1.00 68.43  ? 481 LYS A C   1 
ATOM   3580 O O   . LYS A 1 481 ? 149.618 110.372 101.247 1.00 68.43  ? 481 LYS A O   1 
ATOM   3581 C CB  . LYS A 1 481 ? 151.783 111.995 101.840 1.00 68.43  ? 481 LYS A CB  1 
ATOM   3582 C CG  . LYS A 1 481 ? 153.017 112.650 102.432 1.00 68.43  ? 481 LYS A CG  1 
ATOM   3583 C CD  . LYS A 1 481 ? 154.271 112.185 101.712 1.00 68.43  ? 481 LYS A CD  1 
ATOM   3584 C CE  . LYS A 1 481 ? 155.529 112.629 102.438 1.00 68.43  ? 481 LYS A CE  1 
ATOM   3585 N NZ  . LYS A 1 481 ? 156.749 112.024 101.833 1.00 68.43  ? 481 LYS A NZ  1 
ATOM   3586 N N   . MET A 1 482 ? 148.266 111.246 102.825 1.00 70.81  ? 482 MET A N   1 
ATOM   3587 C CA  . MET A 1 482 ? 147.081 110.539 102.373 1.00 70.81  ? 482 MET A CA  1 
ATOM   3588 C C   . MET A 1 482 ? 146.365 111.348 101.294 1.00 70.81  ? 482 MET A C   1 
ATOM   3589 O O   . MET A 1 482 ? 146.811 112.420 100.879 1.00 70.81  ? 482 MET A O   1 
ATOM   3590 C CB  . MET A 1 482 ? 146.139 110.270 103.544 1.00 70.81  ? 482 MET A CB  1 
ATOM   3591 C CG  . MET A 1 482 ? 146.536 109.104 104.423 1.00 70.81  ? 482 MET A CG  1 
ATOM   3592 S SD  . MET A 1 482 ? 145.282 108.776 105.676 1.00 70.81  ? 482 MET A SD  1 
ATOM   3593 C CE  . MET A 1 482 ? 146.284 108.630 107.153 1.00 70.81  ? 482 MET A CE  1 
ATOM   3594 N N   . GLU A 1 483 ? 145.234 110.821 100.831 1.00 70.43  ? 483 GLU A N   1 
ATOM   3595 C CA  . GLU A 1 483 ? 144.371 111.543 99.913  1.00 70.43  ? 483 GLU A CA  1 
ATOM   3596 C C   . GLU A 1 483 ? 143.597 112.627 100.664 1.00 70.43  ? 483 GLU A C   1 
ATOM   3597 O O   . GLU A 1 483 ? 143.356 112.504 101.868 1.00 70.43  ? 483 GLU A O   1 
ATOM   3598 C CB  . GLU A 1 483 ? 143.407 110.579 99.226  1.00 70.43  ? 483 GLU A CB  1 
ATOM   3599 C CG  . GLU A 1 483 ? 142.832 109.523 100.143 1.00 70.43  ? 483 GLU A CG  1 
ATOM   3600 C CD  . GLU A 1 483 ? 142.194 108.375 99.387  1.00 70.43  ? 483 GLU A CD  1 
ATOM   3601 O OE1 . GLU A 1 483 ? 142.024 108.491 98.155  1.00 70.43  ? 483 GLU A OE1 1 
ATOM   3602 O OE2 . GLU A 1 483 ? 141.855 107.359 100.029 1.00 70.43  ? 483 GLU A OE2 1 
ATOM   3603 N N   . PRO A 1 484 ? 143.205 113.708 99.979  1.00 67.64  ? 484 PRO A N   1 
ATOM   3604 C CA  . PRO A 1 484 ? 142.622 114.859 100.686 1.00 67.64  ? 484 PRO A CA  1 
ATOM   3605 C C   . PRO A 1 484 ? 141.270 114.602 101.337 1.00 67.64  ? 484 PRO A C   1 
ATOM   3606 O O   . PRO A 1 484 ? 141.085 114.905 102.519 1.00 67.64  ? 484 PRO A O   1 
ATOM   3607 C CB  . PRO A 1 484 ? 142.501 115.916 99.579  1.00 67.64  ? 484 PRO A CB  1 
ATOM   3608 C CG  . PRO A 1 484 ? 143.491 115.498 98.544  1.00 67.64  ? 484 PRO A CG  1 
ATOM   3609 C CD  . PRO A 1 484 ? 143.443 114.008 98.557  1.00 67.64  ? 484 PRO A CD  1 
ATOM   3610 N N   . ILE A 1 485 ? 140.318 114.050 100.585 1.00 61.58  ? 485 ILE A N   1 
ATOM   3611 C CA  . ILE A 1 485 ? 138.939 114.003 101.063 1.00 61.58  ? 485 ILE A CA  1 
ATOM   3612 C C   . ILE A 1 485 ? 138.736 112.885 102.087 1.00 61.58  ? 485 ILE A C   1 
ATOM   3613 O O   . ILE A 1 485 ? 137.932 113.031 103.023 1.00 61.58  ? 485 ILE A O   1 
ATOM   3614 C CB  . ILE A 1 485 ? 137.988 113.874 99.859  1.00 61.58  ? 485 ILE A CB  1 
ATOM   3615 C CG1 . ILE A 1 485 ? 137.847 115.227 99.163  1.00 61.58  ? 485 ILE A CG1 1 
ATOM   3616 C CG2 . ILE A 1 485 ? 136.612 113.380 100.276 1.00 61.58  ? 485 ILE A CG2 1 
ATOM   3617 C CD1 . ILE A 1 485 ? 137.230 116.296 100.035 1.00 61.58  ? 485 ILE A CD1 1 
ATOM   3618 N N   . SER A 1 486 ? 139.463 111.773 101.950 1.00 54.97  ? 486 SER A N   1 
ATOM   3619 C CA  . SER A 1 486 ? 139.315 110.681 102.905 1.00 54.97  ? 486 SER A CA  1 
ATOM   3620 C C   . SER A 1 486 ? 139.754 111.092 104.302 1.00 54.97  ? 486 SER A C   1 
ATOM   3621 O O   . SER A 1 486 ? 139.274 110.528 105.287 1.00 54.97  ? 486 SER A O   1 
ATOM   3622 C CB  . SER A 1 486 ? 140.103 109.456 102.448 1.00 54.97  ? 486 SER A CB  1 
ATOM   3623 O OG  . SER A 1 486 ? 141.403 109.453 103.011 1.00 54.97  ? 486 SER A OG  1 
ATOM   3624 N N   . ILE A 1 487 ? 140.654 112.073 104.411 1.00 50.53  ? 487 ILE A N   1 
ATOM   3625 C CA  . ILE A 1 487 ? 141.029 112.595 105.724 1.00 50.53  ? 487 ILE A CA  1 
ATOM   3626 C C   . ILE A 1 487 ? 139.823 113.234 106.402 1.00 50.53  ? 487 ILE A C   1 
ATOM   3627 O O   . ILE A 1 487 ? 139.519 112.951 107.570 1.00 50.53  ? 487 ILE A O   1 
ATOM   3628 C CB  . ILE A 1 487 ? 142.194 113.593 105.590 1.00 50.53  ? 487 ILE A CB  1 
ATOM   3629 C CG1 . ILE A 1 487 ? 143.472 112.869 105.165 1.00 50.53  ? 487 ILE A CG1 1 
ATOM   3630 C CG2 . ILE A 1 487 ? 142.408 114.345 106.892 1.00 50.53  ? 487 ILE A CG2 1 
ATOM   3631 C CD1 . ILE A 1 487 ? 144.650 113.793 104.954 1.00 50.53  ? 487 ILE A CD1 1 
ATOM   3632 N N   . ILE A 1 488 ? 139.109 114.093 105.668 1.00 44.25  ? 488 ILE A N   1 
ATOM   3633 C CA  . ILE A 1 488 ? 137.894 114.714 106.189 1.00 44.25  ? 488 ILE A CA  1 
ATOM   3634 C C   . ILE A 1 488 ? 136.873 113.650 106.561 1.00 44.25  ? 488 ILE A C   1 
ATOM   3635 O O   . ILE A 1 488 ? 136.256 113.702 107.634 1.00 44.25  ? 488 ILE A O   1 
ATOM   3636 C CB  . ILE A 1 488 ? 137.322 115.704 105.156 1.00 44.25  ? 488 ILE A CB  1 
ATOM   3637 C CG1 . ILE A 1 488 ? 138.157 116.981 105.107 1.00 44.25  ? 488 ILE A CG1 1 
ATOM   3638 C CG2 . ILE A 1 488 ? 135.872 116.034 105.468 1.00 44.25  ? 488 ILE A CG2 1 
ATOM   3639 C CD1 . ILE A 1 488 ? 138.166 117.741 106.404 1.00 44.25  ? 488 ILE A CD1 1 
ATOM   3640 N N   . GLY A 1 489 ? 136.688 112.664 105.682 1.00 48.27  ? 489 GLY A N   1 
ATOM   3641 C CA  . GLY A 1 489 ? 135.710 111.621 105.949 1.00 48.27  ? 489 GLY A CA  1 
ATOM   3642 C C   . GLY A 1 489 ? 136.033 110.822 107.198 1.00 48.27  ? 489 GLY A C   1 
ATOM   3643 O O   . GLY A 1 489 ? 135.169 110.596 108.049 1.00 48.27  ? 489 GLY A O   1 
ATOM   3644 N N   . ALA A 1 490 ? 137.293 110.404 107.334 1.00 42.63  ? 490 ALA A N   1 
ATOM   3645 C CA  . ALA A 1 490 ? 137.696 109.607 108.486 1.00 42.63  ? 490 ALA A CA  1 
ATOM   3646 C C   . ALA A 1 490 ? 137.595 110.404 109.777 1.00 42.63  ? 490 ALA A C   1 
ATOM   3647 O O   . ALA A 1 490 ? 137.155 109.873 110.801 1.00 42.63  ? 490 ALA A O   1 
ATOM   3648 C CB  . ALA A 1 490 ? 139.115 109.081 108.288 1.00 42.63  ? 490 ALA A CB  1 
ATOM   3649 N N   . GLN A 1 491 ? 137.987 111.680 109.754 1.00 44.08  ? 491 GLN A N   1 
ATOM   3650 C CA  . GLN A 1 491 ? 137.897 112.480 110.971 1.00 44.08  ? 491 GLN A CA  1 
ATOM   3651 C C   . GLN A 1 491 ? 136.446 112.720 111.372 1.00 44.08  ? 491 GLN A C   1 
ATOM   3652 O O   . GLN A 1 491 ? 136.095 112.598 112.554 1.00 44.08  ? 491 GLN A O   1 
ATOM   3653 C CB  . GLN A 1 491 ? 138.636 113.802 110.783 1.00 44.08  ? 491 GLN A CB  1 
ATOM   3654 C CG  . GLN A 1 491 ? 140.133 113.629 110.616 1.00 44.08  ? 491 GLN A CG  1 
ATOM   3655 C CD  . GLN A 1 491 ? 140.855 114.939 110.395 1.00 44.08  ? 491 GLN A CD  1 
ATOM   3656 O OE1 . GLN A 1 491 ? 142.069 114.965 110.215 1.00 44.08  ? 491 GLN A OE1 1 
ATOM   3657 N NE2 . GLN A 1 491 ? 140.112 116.037 110.415 1.00 44.08  ? 491 GLN A NE2 1 
ATOM   3658 N N   . THR A 1 492 ? 135.579 113.028 110.403 1.00 42.09  ? 492 THR A N   1 
ATOM   3659 C CA  . THR A 1 492 ? 134.178 113.268 110.722 1.00 42.09  ? 492 THR A CA  1 
ATOM   3660 C C   . THR A 1 492 ? 133.432 111.989 111.073 1.00 42.09  ? 492 THR A C   1 
ATOM   3661 O O   . THR A 1 492 ? 132.362 112.062 111.686 1.00 42.09  ? 492 THR A O   1 
ATOM   3662 C CB  . THR A 1 492 ? 133.484 113.990 109.561 1.00 42.09  ? 492 THR A CB  1 
ATOM   3663 O OG1 . THR A 1 492 ? 132.376 114.750 110.060 1.00 42.09  ? 492 THR A OG1 1 
ATOM   3664 C CG2 . THR A 1 492 ? 132.990 113.007 108.515 1.00 42.09  ? 492 THR A CG2 1 
ATOM   3665 N N   . GLY A 1 493 ? 133.960 110.827 110.696 1.00 40.32  ? 493 GLY A N   1 
ATOM   3666 C CA  . GLY A 1 493 ? 133.381 109.578 111.142 1.00 40.32  ? 493 GLY A CA  1 
ATOM   3667 C C   . GLY A 1 493 ? 133.850 109.188 112.529 1.00 40.32  ? 493 GLY A C   1 
ATOM   3668 O O   . GLY A 1 493 ? 133.070 108.671 113.334 1.00 40.32  ? 493 GLY A O   1 
ATOM   3669 N N   . ALA A 1 494 ? 135.135 109.421 112.811 1.00 37.63  ? 494 ALA A N   1 
ATOM   3670 C CA  . ALA A 1 494 ? 135.677 109.121 114.132 1.00 37.63  ? 494 ALA A CA  1 
ATOM   3671 C C   . ALA A 1 494 ? 135.063 110.015 115.200 1.00 37.63  ? 494 ALA A C   1 
ATOM   3672 O O   . ALA A 1 494 ? 134.775 109.555 116.310 1.00 37.63  ? 494 ALA A O   1 
ATOM   3673 C CB  . ALA A 1 494 ? 137.197 109.268 114.120 1.00 37.63  ? 494 ALA A CB  1 
ATOM   3674 N N   . ASP A 1 495 ? 134.858 111.297 114.890 1.00 37.66  ? 495 ASP A N   1 
ATOM   3675 C CA  . ASP A 1 495 ? 134.235 112.184 115.863 1.00 37.66  ? 495 ASP A CA  1 
ATOM   3676 C C   . ASP A 1 495 ? 132.730 111.967 115.970 1.00 37.66  ? 495 ASP A C   1 
ATOM   3677 O O   . ASP A 1 495 ? 132.102 112.551 116.860 1.00 37.66  ? 495 ASP A O   1 
ATOM   3678 C CB  . ASP A 1 495 ? 134.527 113.643 115.520 1.00 37.66  ? 495 ASP A CB  1 
ATOM   3679 C CG  . ASP A 1 495 ? 134.535 114.530 116.745 1.00 37.66  ? 495 ASP A CG  1 
ATOM   3680 O OD1 . ASP A 1 495 ? 134.389 113.992 117.862 1.00 37.66  ? 495 ASP A OD1 1 
ATOM   3681 O OD2 . ASP A 1 495 ? 134.684 115.760 116.593 1.00 37.66  ? 495 ASP A OD2 1 
ATOM   3682 N N   . THR A 1 496 ? 132.149 111.147 115.087 1.00 37.33  ? 496 THR A N   1 
ATOM   3683 C CA  . THR A 1 496 ? 130.729 110.776 115.112 1.00 37.33  ? 496 THR A CA  1 
ATOM   3684 C C   . THR A 1 496 ? 129.821 112.004 115.052 1.00 37.33  ? 496 THR A C   1 
ATOM   3685 O O   . THR A 1 496 ? 128.955 112.206 115.903 1.00 37.33  ? 496 THR A O   1 
ATOM   3686 C CB  . THR A 1 496 ? 130.389 109.913 116.333 1.00 37.33  ? 496 THR A CB  1 
ATOM   3687 O OG1 . THR A 1 496 ? 130.648 110.640 117.539 1.00 37.33  ? 496 THR A OG1 1 
ATOM   3688 C CG2 . THR A 1 496 ? 131.221 108.646 116.332 1.00 37.33  ? 496 THR A CG2 1 
ATOM   3689 N N   . LEU A 1 497 ? 130.033 112.840 114.038 1.00 41.48  ? 497 LEU A N   1 
ATOM   3690 C CA  . LEU A 1 497 ? 129.244 114.053 113.852 1.00 41.48  ? 497 LEU A CA  1 
ATOM   3691 C C   . LEU A 1 497 ? 128.287 113.878 112.678 1.00 41.48  ? 497 LEU A C   1 
ATOM   3692 O O   . LEU A 1 497 ? 128.681 114.026 111.515 1.00 41.48  ? 497 LEU A O   1 
ATOM   3693 C CB  . LEU A 1 497 ? 130.157 115.254 113.641 1.00 41.48  ? 497 LEU A CB  1 
ATOM   3694 C CG  . LEU A 1 497 ? 130.748 115.772 114.943 1.00 41.48  ? 497 LEU A CG  1 
ATOM   3695 C CD1 . LEU A 1 497 ? 132.056 116.444 114.656 1.00 41.48  ? 497 LEU A CD1 1 
ATOM   3696 C CD2 . LEU A 1 497 ? 129.783 116.730 115.617 1.00 41.48  ? 497 LEU A CD2 1 
ATOM   3697 N N   . SER A 1 498 ? 127.019 113.609 112.990 1.00 48.48  ? 498 SER A N   1 
ATOM   3698 C CA  . SER A 1 498 ? 126.007 113.444 111.953 1.00 48.48  ? 498 SER A CA  1 
ATOM   3699 C C   . SER A 1 498 ? 125.681 114.768 111.276 1.00 48.48  ? 498 SER A C   1 
ATOM   3700 O O   . SER A 1 498 ? 125.405 114.799 110.071 1.00 48.48  ? 498 SER A O   1 
ATOM   3701 C CB  . SER A 1 498 ? 124.745 112.826 112.553 1.00 48.48  ? 498 SER A CB  1 
ATOM   3702 O OG  . SER A 1 498 ? 125.060 111.679 113.322 1.00 48.48  ? 498 SER A OG  1 
ATOM   3703 N N   . ALA A 1 499 ? 125.704 115.869 112.032 1.00 50.74  ? 499 ALA A N   1 
ATOM   3704 C CA  . ALA A 1 499 ? 125.483 117.180 111.430 1.00 50.74  ? 499 ALA A CA  1 
ATOM   3705 C C   . ALA A 1 499 ? 126.579 117.517 110.428 1.00 50.74  ? 499 ALA A C   1 
ATOM   3706 O O   . ALA A 1 499 ? 126.295 118.009 109.329 1.00 50.74  ? 499 ALA A O   1 
ATOM   3707 C CB  . ALA A 1 499 ? 125.400 118.251 112.517 1.00 50.74  ? 499 ALA A CB  1 
ATOM   3708 N N   . ALA A 1 500 ? 127.837 117.251 110.789 1.00 53.15  ? 500 ALA A N   1 
ATOM   3709 C CA  . ALA A 1 500 ? 128.937 117.473 109.856 1.00 53.15  ? 500 ALA A CA  1 
ATOM   3710 C C   . ALA A 1 500 ? 128.831 116.548 108.652 1.00 53.15  ? 500 ALA A C   1 
ATOM   3711 O O   . ALA A 1 500 ? 129.100 116.963 107.517 1.00 53.15  ? 500 ALA A O   1 
ATOM   3712 C CB  . ALA A 1 500 ? 130.277 117.282 110.564 1.00 53.15  ? 500 ALA A CB  1 
ATOM   3713 N N   . LEU A 1 501 ? 128.442 115.290 108.884 1.00 52.92  ? 501 LEU A N   1 
ATOM   3714 C CA  . LEU A 1 501 ? 128.219 114.353 107.785 1.00 52.92  ? 501 LEU A CA  1 
ATOM   3715 C C   . LEU A 1 501 ? 127.207 114.910 106.793 1.00 52.92  ? 501 LEU A C   1 
ATOM   3716 O O   . LEU A 1 501 ? 127.470 114.973 105.587 1.00 52.92  ? 501 LEU A O   1 
ATOM   3717 C CB  . LEU A 1 501 ? 127.742 113.009 108.344 1.00 52.92  ? 501 LEU A CB  1 
ATOM   3718 C CG  . LEU A 1 501 ? 127.911 111.701 107.559 1.00 52.92  ? 501 LEU A CG  1 
ATOM   3719 C CD1 . LEU A 1 501 ? 127.700 110.520 108.492 1.00 52.92  ? 501 LEU A CD1 1 
ATOM   3720 C CD2 . LEU A 1 501 ? 126.964 111.595 106.372 1.00 52.92  ? 501 LEU A CD2 1 
ATOM   3721 N N   . ASN A 1 502 ? 126.046 115.339 107.294 1.00 58.93  ? 502 ASN A N   1 
ATOM   3722 C CA  . ASN A 1 502 ? 124.991 115.843 106.420 1.00 58.93  ? 502 ASN A CA  1 
ATOM   3723 C C   . ASN A 1 502 ? 125.415 117.122 105.710 1.00 58.93  ? 502 ASN A C   1 
ATOM   3724 O O   . ASN A 1 502 ? 125.128 117.302 104.520 1.00 58.93  ? 502 ASN A O   1 
ATOM   3725 C CB  . ASN A 1 502 ? 123.713 116.075 107.224 1.00 58.93  ? 502 ASN A CB  1 
ATOM   3726 C CG  . ASN A 1 502 ? 123.113 114.786 107.744 1.00 58.93  ? 502 ASN A CG  1 
ATOM   3727 O OD1 . ASN A 1 502 ? 123.626 113.699 107.480 1.00 58.93  ? 502 ASN A OD1 1 
ATOM   3728 N ND2 . ASN A 1 502 ? 122.018 114.900 108.487 1.00 58.93  ? 502 ASN A ND2 1 
ATOM   3729 N N   . ASP A 1 503 ? 126.098 118.024 106.420 1.00 58.92  ? 503 ASP A N   1 
ATOM   3730 C CA  . ASP A 1 503 ? 126.491 119.290 105.809 1.00 58.92  ? 503 ASP A CA  1 
ATOM   3731 C C   . ASP A 1 503 ? 127.516 119.079 104.702 1.00 58.92  ? 503 ASP A C   1 
ATOM   3732 O O   . ASP A 1 503 ? 127.391 119.659 103.615 1.00 58.92  ? 503 ASP A O   1 
ATOM   3733 C CB  . ASP A 1 503 ? 127.030 120.241 106.877 1.00 58.92  ? 503 ASP A CB  1 
ATOM   3734 C CG  . ASP A 1 503 ? 127.067 121.683 106.409 1.00 58.92  ? 503 ASP A CG  1 
ATOM   3735 O OD1 . ASP A 1 503 ? 126.625 121.959 105.274 1.00 58.92  ? 503 ASP A OD1 1 
ATOM   3736 O OD2 . ASP A 1 503 ? 127.523 122.546 107.187 1.00 58.92  ? 503 ASP A OD2 1 
ATOM   3737 N N   . VAL A 1 504 ? 128.529 118.244 104.944 1.00 59.13  ? 504 VAL A N   1 
ATOM   3738 C CA  . VAL A 1 504 ? 129.513 117.985 103.898 1.00 59.13  ? 504 VAL A CA  1 
ATOM   3739 C C   . VAL A 1 504 ? 128.873 117.222 102.743 1.00 59.13  ? 504 VAL A C   1 
ATOM   3740 O O   . VAL A 1 504 ? 129.196 117.463 101.575 1.00 59.13  ? 504 VAL A O   1 
ATOM   3741 C CB  . VAL A 1 504 ? 130.735 117.245 104.471 1.00 59.13  ? 504 VAL A CB  1 
ATOM   3742 C CG1 . VAL A 1 504 ? 131.734 116.941 103.367 1.00 59.13  ? 504 VAL A CG1 1 
ATOM   3743 C CG2 . VAL A 1 504 ? 131.397 118.081 105.552 1.00 59.13  ? 504 VAL A CG2 1 
ATOM   3744 N N   . SER A 1 505 ? 127.937 116.315 103.042 1.00 61.42  ? 505 SER A N   1 
ATOM   3745 C CA  . SER A 1 505 ? 127.269 115.568 101.980 1.00 61.42  ? 505 SER A CA  1 
ATOM   3746 C C   . SER A 1 505 ? 126.443 116.486 101.086 1.00 61.42  ? 505 SER A C   1 
ATOM   3747 O O   . SER A 1 505 ? 126.425 116.317 99.862  1.00 61.42  ? 505 SER A O   1 
ATOM   3748 C CB  . SER A 1 505 ? 126.388 114.475 102.582 1.00 61.42  ? 505 SER A CB  1 
ATOM   3749 O OG  . SER A 1 505 ? 125.237 114.255 101.785 1.00 61.42  ? 505 SER A OG  1 
ATOM   3750 N N   . GLU A 1 506 ? 125.746 117.459 101.676 1.00 66.65  ? 506 GLU A N   1 
ATOM   3751 C CA  . GLU A 1 506 ? 124.945 118.364 100.859 1.00 66.65  ? 506 GLU A CA  1 
ATOM   3752 C C   . GLU A 1 506 ? 125.814 119.381 100.127 1.00 66.65  ? 506 GLU A C   1 
ATOM   3753 O O   . GLU A 1 506 ? 125.454 119.819 99.029  1.00 66.65  ? 506 GLU A O   1 
ATOM   3754 C CB  . GLU A 1 506 ? 123.880 119.060 101.715 1.00 66.65  ? 506 GLU A CB  1 
ATOM   3755 C CG  . GLU A 1 506 ? 124.389 120.095 102.712 1.00 66.65  ? 506 GLU A CG  1 
ATOM   3756 C CD  . GLU A 1 506 ? 124.471 121.495 102.128 1.00 66.65  ? 506 GLU A CD  1 
ATOM   3757 O OE1 . GLU A 1 506 ? 123.953 121.706 101.011 1.00 66.65  ? 506 GLU A OE1 1 
ATOM   3758 O OE2 . GLU A 1 506 ? 125.055 122.382 102.784 1.00 66.65  ? 506 GLU A OE2 1 
ATOM   3759 N N   . ARG A 1 507 ? 126.954 119.769 100.708 1.00 63.37  ? 507 ARG A N   1 
ATOM   3760 C CA  . ARG A 1 507 ? 127.833 120.712 100.023 1.00 63.37  ? 507 ARG A CA  1 
ATOM   3761 C C   . ARG A 1 507 ? 128.584 120.048 98.874  1.00 63.37  ? 507 ARG A C   1 
ATOM   3762 O O   . ARG A 1 507 ? 128.855 120.689 97.852  1.00 63.37  ? 507 ARG A O   1 
ATOM   3763 C CB  . ARG A 1 507 ? 128.817 121.334 101.014 1.00 63.37  ? 507 ARG A CB  1 
ATOM   3764 C CG  . ARG A 1 507 ? 129.599 122.507 100.447 1.00 63.37  ? 507 ARG A CG  1 
ATOM   3765 C CD  . ARG A 1 507 ? 128.782 123.788 100.454 1.00 63.37  ? 507 ARG A CD  1 
ATOM   3766 N NE  . ARG A 1 507 ? 128.588 124.310 101.800 1.00 63.37  ? 507 ARG A NE  1 
ATOM   3767 C CZ  . ARG A 1 507 ? 129.489 125.021 102.465 1.00 63.37  ? 507 ARG A CZ  1 
ATOM   3768 N NH1 . ARG A 1 507 ? 130.669 125.308 101.939 1.00 63.37  ? 507 ARG A NH1 1 
ATOM   3769 N NH2 . ARG A 1 507 ? 129.198 125.457 103.686 1.00 63.37  ? 507 ARG A NH2 1 
ATOM   3770 N N   . VAL A 1 508 ? 128.928 118.767 99.020  1.00 66.47  ? 508 VAL A N   1 
ATOM   3771 C CA  . VAL A 1 508 ? 129.785 118.114 98.038  1.00 66.47  ? 508 VAL A CA  1 
ATOM   3772 C C   . VAL A 1 508 ? 129.039 117.843 96.735  1.00 66.47  ? 508 VAL A C   1 
ATOM   3773 O O   . VAL A 1 508 ? 129.659 117.760 95.668  1.00 66.47  ? 508 VAL A O   1 
ATOM   3774 C CB  . VAL A 1 508 ? 130.386 116.830 98.644  1.00 66.47  ? 508 VAL A CB  1 
ATOM   3775 C CG1 . VAL A 1 508 ? 129.420 115.660 98.545  1.00 66.47  ? 508 VAL A CG1 1 
ATOM   3776 C CG2 . VAL A 1 508 ? 131.692 116.499 97.969  1.00 66.47  ? 508 VAL A CG2 1 
ATOM   3777 N N   . GLY A 1 509 ? 127.727 117.705 96.787  1.00 77.29  ? 509 GLY A N   1 
ATOM   3778 C CA  . GLY A 1 509 ? 126.986 117.390 95.586  1.00 77.29  ? 509 GLY A CA  1 
ATOM   3779 C C   . GLY A 1 509 ? 126.509 115.948 95.585  1.00 77.29  ? 509 GLY A C   1 
ATOM   3780 O O   . GLY A 1 509 ? 127.061 115.078 96.272  1.00 77.29  ? 509 GLY A O   1 
ATOM   3781 N N   . SER A 1 510 ? 125.460 115.689 94.802  1.00 82.55  ? 510 SER A N   1 
ATOM   3782 C CA  . SER A 1 510 ? 124.890 114.347 94.753  1.00 82.55  ? 510 SER A CA  1 
ATOM   3783 C C   . SER A 1 510 ? 125.802 113.364 94.030  1.00 82.55  ? 510 SER A C   1 
ATOM   3784 O O   . SER A 1 510 ? 125.696 112.152 94.250  1.00 82.55  ? 510 SER A O   1 
ATOM   3785 C CB  . SER A 1 510 ? 123.517 114.385 94.083  1.00 82.55  ? 510 SER A CB  1 
ATOM   3786 O OG  . SER A 1 510 ? 122.997 113.078 93.913  1.00 82.55  ? 510 SER A OG  1 
ATOM   3787 N N   . ASP A 1 511 ? 126.683 113.855 93.155  1.00 87.54  ? 511 ASP A N   1 
ATOM   3788 C CA  . ASP A 1 511 ? 127.531 112.958 92.375  1.00 87.54  ? 511 ASP A CA  1 
ATOM   3789 C C   . ASP A 1 511 ? 128.519 112.200 93.256  1.00 87.54  ? 511 ASP A C   1 
ATOM   3790 O O   . ASP A 1 511 ? 128.762 111.008 93.038  1.00 87.54  ? 511 ASP A O   1 
ATOM   3791 C CB  . ASP A 1 511 ? 128.268 113.743 91.291  1.00 87.54  ? 511 ASP A CB  1 
ATOM   3792 C CG  . ASP A 1 511 ? 128.729 115.105 91.769  1.00 87.54  ? 511 ASP A CG  1 
ATOM   3793 O OD1 . ASP A 1 511 ? 128.577 115.394 92.974  1.00 87.54  ? 511 ASP A OD1 1 
ATOM   3794 O OD2 . ASP A 1 511 ? 129.243 115.886 90.941  1.00 87.54  ? 511 ASP A OD2 1 
ATOM   3795 N N   . ALA A 1 512 ? 129.101 112.869 94.251  1.00 78.33  ? 512 ALA A N   1 
ATOM   3796 C CA  . ALA A 1 512 ? 130.111 112.265 95.112  1.00 78.33  ? 512 ALA A CA  1 
ATOM   3797 C C   . ALA A 1 512 ? 129.576 111.896 96.491  1.00 78.33  ? 512 ALA A C   1 
ATOM   3798 O O   . ALA A 1 512 ? 130.367 111.581 97.392  1.00 78.33  ? 512 ALA A O   1 
ATOM   3799 C CB  . ALA A 1 512 ? 131.309 113.205 95.252  1.00 78.33  ? 512 ALA A CB  1 
ATOM   3800 N N   . SER A 1 513 ? 128.253 111.975 96.645  1.00 69.10  ? 513 SER A N   1 
ATOM   3801 C CA  . SER A 1 513 ? 127.616 111.626 97.938  1.00 69.10  ? 513 SER A CA  1 
ATOM   3802 C C   . SER A 1 513 ? 127.825 110.141 98.262  1.00 69.10  ? 513 SER A C   1 
ATOM   3803 O O   . SER A 1 513 ? 128.071 109.850 99.445  1.00 69.10  ? 513 SER A O   1 
ATOM   3804 C CB  . SER A 1 513 ? 126.168 111.991 97.940  1.00 69.10  ? 513 SER A CB  1 
ATOM   3805 O OG  . SER A 1 513 ? 125.577 111.652 99.186  1.00 69.10  ? 513 SER A OG  1 
ATOM   3806 N N   . PRO A 1 514 ? 127.736 109.177 97.318  1.00 68.48  ? 514 PRO A N   1 
ATOM   3807 C CA  . PRO A 1 514 ? 128.036 107.787 97.640  1.00 68.48  ? 514 PRO A CA  1 
ATOM   3808 C C   . PRO A 1 514 ? 129.526 107.574 97.832  1.00 68.48  ? 514 PRO A C   1 
ATOM   3809 O O   . PRO A 1 514 ? 129.931 106.436 98.123  1.00 68.48  ? 514 PRO A O   1 
ATOM   3810 C CB  . PRO A 1 514 ? 127.508 106.987 96.452  1.00 68.48  ? 514 PRO A CB  1 
ATOM   3811 C CG  . PRO A 1 514 ? 126.645 107.973 95.695  1.00 68.48  ? 514 PRO A CG  1 
ATOM   3812 C CD  . PRO A 1 514 ? 127.267 109.333 95.954  1.00 68.48  ? 514 PRO A CD  1 
ATOM   3813 N N   . PHE A 1 515 ? 130.330 108.619 97.631  1.00 67.18  ? 515 PHE A N   1 
ATOM   3814 C CA  . PHE A 1 515 ? 131.787 108.513 97.907  1.00 67.18  ? 515 PHE A CA  1 
ATOM   3815 C C   . PHE A 1 515 ? 131.999 108.934 99.347  1.00 67.18  ? 515 PHE A C   1 
ATOM   3816 O O   . PHE A 1 515 ? 132.600 108.177 100.130 1.00 67.18  ? 515 PHE A O   1 
ATOM   3817 C CB  . PHE A 1 515 ? 132.621 109.388 96.967  1.00 67.18  ? 515 PHE A CB  1 
ATOM   3818 C CG  . PHE A 1 515 ? 134.109 109.429 97.282  1.00 67.18  ? 515 PHE A CG  1 
ATOM   3819 C CD1 . PHE A 1 515 ? 134.976 108.490 96.741  1.00 67.18  ? 515 PHE A CD1 1 
ATOM   3820 C CD2 . PHE A 1 515 ? 134.636 110.405 98.117  1.00 67.18  ? 515 PHE A CD2 1 
ATOM   3821 C CE1 . PHE A 1 515 ? 136.330 108.529 97.028  1.00 67.18  ? 515 PHE A CE1 1 
ATOM   3822 C CE2 . PHE A 1 515 ? 135.991 110.438 98.401  1.00 67.18  ? 515 PHE A CE2 1 
ATOM   3823 C CZ  . PHE A 1 515 ? 136.833 109.501 97.857  1.00 67.18  ? 515 PHE A CZ  1 
ATOM   3824 N N   . PHE A 1 516 ? 131.492 110.116 99.697  1.00 57.81  ? 516 PHE A N   1 
ATOM   3825 C CA  . PHE A 1 516 ? 131.623 110.588 101.072 1.00 57.81  ? 516 PHE A CA  1 
ATOM   3826 C C   . PHE A 1 516 ? 131.009 109.599 102.056 1.00 57.81  ? 516 PHE A C   1 
ATOM   3827 O O   . PHE A 1 516 ? 131.554 109.384 103.146 1.00 57.81  ? 516 PHE A O   1 
ATOM   3828 C CB  . PHE A 1 516 ? 130.991 111.968 101.235 1.00 57.81  ? 516 PHE A CB  1 
ATOM   3829 C CG  . PHE A 1 516 ? 131.360 112.643 102.526 1.00 57.81  ? 516 PHE A CG  1 
ATOM   3830 C CD1 . PHE A 1 516 ? 132.670 113.018 102.775 1.00 57.81  ? 516 PHE A CD1 1 
ATOM   3831 C CD2 . PHE A 1 516 ? 130.405 112.878 103.502 1.00 57.81  ? 516 PHE A CD2 1 
ATOM   3832 C CE1 . PHE A 1 516 ? 133.019 113.629 103.964 1.00 57.81  ? 516 PHE A CE1 1 
ATOM   3833 C CE2 . PHE A 1 516 ? 130.749 113.489 104.694 1.00 57.81  ? 516 PHE A CE2 1 
ATOM   3834 C CZ  . PHE A 1 516 ? 132.057 113.861 104.926 1.00 57.81  ? 516 PHE A CZ  1 
ATOM   3835 N N   . ALA A 1 517 ? 129.875 108.989 101.696 1.00 54.67  ? 517 ALA A N   1 
ATOM   3836 C CA  . ALA A 1 517 ? 129.266 107.993 102.572 1.00 54.67  ? 517 ALA A CA  1 
ATOM   3837 C C   . ALA A 1 517 ? 130.180 106.787 102.756 1.00 54.67  ? 517 ALA A C   1 
ATOM   3838 O O   . ALA A 1 517 ? 130.295 106.249 103.864 1.00 54.67  ? 517 ALA A O   1 
ATOM   3839 C CB  . ALA A 1 517 ? 127.910 107.562 102.016 1.00 54.67  ? 517 ALA A CB  1 
ATOM   3840 N N   . ALA A 1 518 ? 130.836 106.342 101.680 1.00 51.66  ? 518 ALA A N   1 
ATOM   3841 C CA  . ALA A 1 518 ? 131.784 105.241 101.806 1.00 51.66  ? 518 ALA A CA  1 
ATOM   3842 C C   . ALA A 1 518 ? 133.010 105.650 102.610 1.00 51.66  ? 518 ALA A C   1 
ATOM   3843 O O   . ALA A 1 518 ? 133.592 104.819 103.314 1.00 51.66  ? 518 ALA A O   1 
ATOM   3844 C CB  . ALA A 1 518 ? 132.195 104.737 100.422 1.00 51.66  ? 518 ALA A CB  1 
ATOM   3845 N N   . ALA A 1 519 ? 133.418 106.916 102.521 1.00 49.29  ? 519 ALA A N   1 
ATOM   3846 C CA  . ALA A 1 519 ? 134.555 107.372 103.313 1.00 49.29  ? 519 ALA A CA  1 
ATOM   3847 C C   . ALA A 1 519 ? 134.223 107.441 104.797 1.00 49.29  ? 519 ALA A C   1 
ATOM   3848 O O   . ALA A 1 519 ? 135.100 107.212 105.636 1.00 49.29  ? 519 ALA A O   1 
ATOM   3849 C CB  . ALA A 1 519 ? 135.029 108.736 102.816 1.00 49.29  ? 519 ALA A CB  1 
ATOM   3850 N N   . VAL A 1 520 ? 132.978 107.761 105.140 1.00 46.75  ? 520 VAL A N   1 
ATOM   3851 C CA  . VAL A 1 520 ? 132.615 107.926 106.545 1.00 46.75  ? 520 VAL A CA  1 
ATOM   3852 C C   . VAL A 1 520 ? 132.164 106.615 107.197 1.00 46.75  ? 520 VAL A C   1 
ATOM   3853 O O   . VAL A 1 520 ? 132.382 106.419 108.398 1.00 46.75  ? 520 VAL A O   1 
ATOM   3854 C CB  . VAL A 1 520 ? 131.536 109.017 106.675 1.00 46.75  ? 520 VAL A CB  1 
ATOM   3855 C CG1 . VAL A 1 520 ? 131.090 109.187 108.120 1.00 46.75  ? 520 VAL A CG1 1 
ATOM   3856 C CG2 . VAL A 1 520 ? 132.059 110.336 106.138 1.00 46.75  ? 520 VAL A CG2 1 
ATOM   3857 N N   . ALA A 1 521 ? 131.578 105.696 106.426 1.00 43.22  ? 521 ALA A N   1 
ATOM   3858 C CA  . ALA A 1 521 ? 130.901 104.537 107.012 1.00 43.22  ? 521 ALA A CA  1 
ATOM   3859 C C   . ALA A 1 521 ? 131.787 103.646 107.883 1.00 43.22  ? 521 ALA A C   1 
ATOM   3860 O O   . ALA A 1 521 ? 131.343 103.283 108.986 1.00 43.22  ? 521 ALA A O   1 
ATOM   3861 C CB  . ALA A 1 521 ? 130.224 103.727 105.900 1.00 43.22  ? 521 ALA A CB  1 
ATOM   3862 N N   . PRO A 1 522 ? 132.997 103.230 107.474 1.00 41.41  ? 522 PRO A N   1 
ATOM   3863 C CA  . PRO A 1 522 ? 133.793 102.369 108.370 1.00 41.41  ? 522 PRO A CA  1 
ATOM   3864 C C   . PRO A 1 522 ? 134.164 103.024 109.688 1.00 41.41  ? 522 PRO A C   1 
ATOM   3865 O O   . PRO A 1 522 ? 134.302 102.327 110.700 1.00 41.41  ? 522 PRO A O   1 
ATOM   3866 C CB  . PRO A 1 522 ? 135.042 102.052 107.536 1.00 41.41  ? 522 PRO A CB  1 
ATOM   3867 C CG  . PRO A 1 522 ? 134.621 102.242 106.141 1.00 41.41  ? 522 PRO A CG  1 
ATOM   3868 C CD  . PRO A 1 522 ? 133.680 103.399 106.179 1.00 41.41  ? 522 PRO A CD  1 
ATOM   3869 N N   . ALA A 1 523 ? 134.341 104.345 109.700 1.00 42.32  ? 523 ALA A N   1 
ATOM   3870 C CA  . ALA A 1 523 ? 134.772 105.036 110.911 1.00 42.32  ? 523 ALA A CA  1 
ATOM   3871 C C   . ALA A 1 523 ? 133.708 104.994 112.000 1.00 42.32  ? 523 ALA A C   1 
ATOM   3872 O O   . ALA A 1 523 ? 134.035 104.893 113.190 1.00 42.32  ? 523 ALA A O   1 
ATOM   3873 C CB  . ALA A 1 523 ? 135.131 106.482 110.578 1.00 42.32  ? 523 ALA A CB  1 
ATOM   3874 N N   . TYR A 1 524 ? 132.433 105.085 111.610 1.00 41.24  ? 524 TYR A N   1 
ATOM   3875 C CA  . TYR A 1 524 ? 131.365 105.381 112.560 1.00 41.24  ? 524 TYR A CA  1 
ATOM   3876 C C   . TYR A 1 524 ? 131.222 104.287 113.614 1.00 41.24  ? 524 TYR A C   1 
ATOM   3877 O O   . TYR A 1 524 ? 131.091 104.579 114.807 1.00 41.24  ? 524 TYR A O   1 
ATOM   3878 C CB  . TYR A 1 524 ? 130.050 105.585 111.809 1.00 41.24  ? 524 TYR A CB  1 
ATOM   3879 C CG  . TYR A 1 524 ? 129.133 106.607 112.440 1.00 41.24  ? 524 TYR A CG  1 
ATOM   3880 C CD1 . TYR A 1 524 ? 128.560 106.386 113.684 1.00 41.24  ? 524 TYR A CD1 1 
ATOM   3881 C CD2 . TYR A 1 524 ? 128.843 107.798 111.789 1.00 41.24  ? 524 TYR A CD2 1 
ATOM   3882 C CE1 . TYR A 1 524 ? 127.722 107.321 114.260 1.00 41.24  ? 524 TYR A CE1 1 
ATOM   3883 C CE2 . TYR A 1 524 ? 128.007 108.738 112.358 1.00 41.24  ? 524 TYR A CE2 1 
ATOM   3884 C CZ  . TYR A 1 524 ? 127.450 108.495 113.593 1.00 41.24  ? 524 TYR A CZ  1 
ATOM   3885 O OH  . TYR A 1 524 ? 126.617 109.428 114.165 1.00 41.24  ? 524 TYR A OH  1 
ATOM   3886 N N   . ALA A 1 525 ? 131.247 103.019 113.194 1.00 41.41  ? 525 ALA A N   1 
ATOM   3887 C CA  . ALA A 1 525 ? 131.009 101.922 114.131 1.00 41.41  ? 525 ALA A CA  1 
ATOM   3888 C C   . ALA A 1 525 ? 132.120 101.822 115.172 1.00 41.41  ? 525 ALA A C   1 
ATOM   3889 O O   . ALA A 1 525 ? 131.853 101.739 116.380 1.00 41.41  ? 525 ALA A O   1 
ATOM   3890 C CB  . ALA A 1 525 ? 130.866 100.605 113.368 1.00 41.41  ? 525 ALA A CB  1 
ATOM   3891 N N   . ILE A 1 526 ? 133.376 101.825 114.717 1.00 41.04  ? 526 ILE A N   1 
ATOM   3892 C CA  . ILE A 1 526 ? 134.511 101.732 115.631 1.00 41.04  ? 526 ILE A CA  1 
ATOM   3893 C C   . ILE A 1 526 ? 134.546 102.939 116.557 1.00 41.04  ? 526 ILE A C   1 
ATOM   3894 O O   . ILE A 1 526 ? 134.770 102.807 117.770 1.00 41.04  ? 526 ILE A O   1 
ATOM   3895 C CB  . ILE A 1 526 ? 135.822 101.589 114.836 1.00 41.04  ? 526 ILE A CB  1 
ATOM   3896 C CG1 . ILE A 1 526 ? 135.797 100.316 113.991 1.00 41.04  ? 526 ILE A CG1 1 
ATOM   3897 C CG2 . ILE A 1 526 ? 137.022 101.587 115.770 1.00 41.04  ? 526 ILE A CG2 1 
ATOM   3898 C CD1 . ILE A 1 526 ? 135.493 99.067  114.785 1.00 41.04  ? 526 ILE A CD1 1 
ATOM   3899 N N   . GLY A 1 527 ? 134.317 104.131 116.001 1.00 39.86  ? 527 GLY A N   1 
ATOM   3900 C CA  . GLY A 1 527 ? 134.297 105.327 116.824 1.00 39.86  ? 527 GLY A CA  1 
ATOM   3901 C C   . GLY A 1 527 ? 133.229 105.274 117.898 1.00 39.86  ? 527 GLY A C   1 
ATOM   3902 O O   . GLY A 1 527 ? 133.488 105.587 119.061 1.00 39.86  ? 527 GLY A O   1 
ATOM   3903 N N   . ASN A 1 528 ? 132.016 104.855 117.524 1.00 40.02  ? 528 ASN A N   1 
ATOM   3904 C CA  . ASN A 1 528 ? 130.927 104.767 118.491 1.00 40.02  ? 528 ASN A CA  1 
ATOM   3905 C C   . ASN A 1 528 ? 131.238 103.763 119.592 1.00 40.02  ? 528 ASN A C   1 
ATOM   3906 O O   . ASN A 1 528 ? 131.049 104.054 120.778 1.00 40.02  ? 528 ASN A O   1 
ATOM   3907 C CB  . ASN A 1 528 ? 129.622 104.402 117.785 1.00 40.02  ? 528 ASN A CB  1 
ATOM   3908 C CG  . ASN A 1 528 ? 128.482 105.328 118.155 1.00 40.02  ? 528 ASN A CG  1 
ATOM   3909 O OD1 . ASN A 1 528 ? 128.102 105.425 119.321 1.00 40.02  ? 528 ASN A OD1 1 
ATOM   3910 N ND2 . ASN A 1 528 ? 127.931 106.017 117.165 1.00 40.02  ? 528 ASN A ND2 1 
ATOM   3911 N N   . ILE A 1 529 ? 131.734 102.578 119.220 1.00 42.05  ? 529 ILE A N   1 
ATOM   3912 C CA  . ILE A 1 529 ? 131.997 101.547 120.223 1.00 42.05  ? 529 ILE A CA  1 
ATOM   3913 C C   . ILE A 1 529 ? 133.083 102.004 121.191 1.00 42.05  ? 529 ILE A C   1 
ATOM   3914 O O   . ILE A 1 529 ? 132.930 101.902 122.419 1.00 42.05  ? 529 ILE A O   1 
ATOM   3915 C CB  . ILE A 1 529 ? 132.365 100.217 119.538 1.00 42.05  ? 529 ILE A CB  1 
ATOM   3916 C CG1 . ILE A 1 529 ? 131.104 99.402  119.253 1.00 42.05  ? 529 ILE A CG1 1 
ATOM   3917 C CG2 . ILE A 1 529 ? 133.325 99.403  120.395 1.00 42.05  ? 529 ILE A CG2 1 
ATOM   3918 C CD1 . ILE A 1 529 ? 131.375 98.106  118.521 1.00 42.05  ? 529 ILE A CD1 1 
ATOM   3919 N N   . PHE A 1 530 ? 134.176 102.560 120.663 1.00 44.03  ? 530 PHE A N   1 
ATOM   3920 C CA  . PHE A 1 530 ? 135.283 102.920 121.539 1.00 44.03  ? 530 PHE A CA  1 
ATOM   3921 C C   . PHE A 1 530 ? 134.959 104.153 122.373 1.00 44.03  ? 530 PHE A C   1 
ATOM   3922 O O   . PHE A 1 530 ? 135.368 104.238 123.536 1.00 44.03  ? 530 PHE A O   1 
ATOM   3923 C CB  . PHE A 1 530 ? 136.552 103.133 120.720 1.00 44.03  ? 530 PHE A CB  1 
ATOM   3924 C CG  . PHE A 1 530 ? 137.453 101.933 120.688 1.00 44.03  ? 530 PHE A CG  1 
ATOM   3925 C CD1 . PHE A 1 530 ? 137.172 100.868 119.849 1.00 44.03  ? 530 PHE A CD1 1 
ATOM   3926 C CD2 . PHE A 1 530 ? 138.570 101.862 121.504 1.00 44.03  ? 530 PHE A CD2 1 
ATOM   3927 C CE1 . PHE A 1 530 ? 137.991 99.757  119.818 1.00 44.03  ? 530 PHE A CE1 1 
ATOM   3928 C CE2 . PHE A 1 530 ? 139.394 100.753 121.477 1.00 44.03  ? 530 PHE A CE2 1 
ATOM   3929 C CZ  . PHE A 1 530 ? 139.104 99.699  120.633 1.00 44.03  ? 530 PHE A CZ  1 
ATOM   3930 N N   . LEU A 1 531 ? 134.200 105.102 121.820 1.00 41.56  ? 531 LEU A N   1 
ATOM   3931 C CA  . LEU A 1 531 ? 133.813 106.268 122.601 1.00 41.56  ? 531 LEU A CA  1 
ATOM   3932 C C   . LEU A 1 531 ? 132.799 105.908 123.677 1.00 41.56  ? 531 LEU A C   1 
ATOM   3933 O O   . LEU A 1 531 ? 132.799 106.517 124.753 1.00 41.56  ? 531 LEU A O   1 
ATOM   3934 C CB  . LEU A 1 531 ? 133.255 107.349 121.678 1.00 41.56  ? 531 LEU A CB  1 
ATOM   3935 C CG  . LEU A 1 531 ? 134.306 108.203 120.968 1.00 41.56  ? 531 LEU A CG  1 
ATOM   3936 C CD1 . LEU A 1 531 ? 133.723 109.546 120.567 1.00 41.56  ? 531 LEU A CD1 1 
ATOM   3937 C CD2 . LEU A 1 531 ? 135.553 108.374 121.820 1.00 41.56  ? 531 LEU A CD2 1 
ATOM   3938 N N   . THR A 1 532 ? 131.921 104.937 123.407 1.00 40.33  ? 532 THR A N   1 
ATOM   3939 C CA  . THR A 1 532 ? 131.029 104.444 124.448 1.00 40.33  ? 532 THR A CA  1 
ATOM   3940 C C   . THR A 1 532 ? 131.816 103.773 125.566 1.00 40.33  ? 532 THR A C   1 
ATOM   3941 O O   . THR A 1 532 ? 131.525 103.978 126.750 1.00 40.33  ? 532 THR A O   1 
ATOM   3942 C CB  . THR A 1 532 ? 130.007 103.479 123.848 1.00 40.33  ? 532 THR A CB  1 
ATOM   3943 O OG1 . THR A 1 532 ? 129.229 104.164 122.859 1.00 40.33  ? 532 THR A OG1 1 
ATOM   3944 C CG2 . THR A 1 532 ? 129.080 102.941 124.924 1.00 40.33  ? 532 THR A CG2 1 
ATOM   3945 N N   . LEU A 1 533 ? 132.832 102.984 125.213 1.00 42.88  ? 533 LEU A N   1 
ATOM   3946 C CA  . LEU A 1 533 ? 133.627 102.327 126.245 1.00 42.88  ? 533 LEU A CA  1 
ATOM   3947 C C   . LEU A 1 533 ? 134.561 103.276 126.990 1.00 42.88  ? 533 LEU A C   1 
ATOM   3948 O O   . LEU A 1 533 ? 134.951 102.965 128.119 1.00 42.88  ? 533 LEU A O   1 
ATOM   3949 C CB  . LEU A 1 533 ? 134.443 101.179 125.646 1.00 42.88  ? 533 LEU A CB  1 
ATOM   3950 C CG  . LEU A 1 533 ? 133.648 99.992  125.102 1.00 42.88  ? 533 LEU A CG  1 
ATOM   3951 C CD1 . LEU A 1 533 ? 134.544 98.772  124.969 1.00 42.88  ? 533 LEU A CD1 1 
ATOM   3952 C CD2 . LEU A 1 533 ? 132.454 99.686  125.991 1.00 42.88  ? 533 LEU A CD2 1 
ATOM   3953 N N   . MET A 1 534 ? 134.923 104.415 126.392 1.00 44.61  ? 534 MET A N   1 
ATOM   3954 C CA  . MET A 1 534 ? 135.908 105.308 127.000 1.00 44.61  ? 534 MET A CA  1 
ATOM   3955 C C   . MET A 1 534 ? 135.442 105.875 128.339 1.00 44.61  ? 534 MET A C   1 
ATOM   3956 O O   . MET A 1 534 ? 136.267 106.118 129.230 1.00 44.61  ? 534 MET A O   1 
ATOM   3957 C CB  . MET A 1 534 ? 136.228 106.450 126.033 1.00 44.61  ? 534 MET A CB  1 
ATOM   3958 C CG  . MET A 1 534 ? 137.426 107.296 126.420 1.00 44.61  ? 534 MET A CG  1 
ATOM   3959 S SD  . MET A 1 534 ? 138.350 107.879 124.986 1.00 44.61  ? 534 MET A SD  1 
ATOM   3960 C CE  . MET A 1 534 ? 139.134 106.366 124.444 1.00 44.61  ? 534 MET A CE  1 
ATOM   3961 N N   . GLY A 1 535 ? 134.138 106.086 128.499 1.00 46.04  ? 535 GLY A N   1 
ATOM   3962 C CA  . GLY A 1 535 ? 133.586 106.755 129.657 1.00 46.04  ? 535 GLY A CA  1 
ATOM   3963 C C   . GLY A 1 535 ? 133.843 106.072 130.988 1.00 46.04  ? 535 GLY A C   1 
ATOM   3964 O O   . GLY A 1 535 ? 134.421 106.664 131.909 1.00 46.04  ? 535 GLY A O   1 
ATOM   3965 N N   . PRO A 1 536 ? 133.357 104.833 131.139 1.00 51.41  ? 536 PRO A N   1 
ATOM   3966 C CA  . PRO A 1 536 ? 133.620 104.098 132.390 1.00 51.41  ? 536 PRO A CA  1 
ATOM   3967 C C   . PRO A 1 536 ? 135.095 103.924 132.701 1.00 51.41  ? 536 PRO A C   1 
ATOM   3968 O O   . PRO A 1 536 ? 135.492 104.018 133.871 1.00 51.41  ? 536 PRO A O   1 
ATOM   3969 C CB  . PRO A 1 536 ? 132.933 102.749 132.143 1.00 51.41  ? 536 PRO A CB  1 
ATOM   3970 C CG  . PRO A 1 536 ? 131.844 103.060 131.185 1.00 51.41  ? 536 PRO A CG  1 
ATOM   3971 C CD  . PRO A 1 536 ? 132.397 104.119 130.277 1.00 51.41  ? 536 PRO A CD  1 
ATOM   3972 N N   . ILE A 1 537 ? 135.922 103.671 131.682 1.00 49.80  ? 537 ILE A N   1 
ATOM   3973 C CA  . ILE A 1 537 ? 137.356 103.531 131.911 1.00 49.80  ? 537 ILE A CA  1 
ATOM   3974 C C   . ILE A 1 537 ? 137.934 104.828 132.453 1.00 49.80  ? 537 ILE A C   1 
ATOM   3975 O O   . ILE A 1 537 ? 138.750 104.818 133.383 1.00 49.80  ? 537 ILE A O   1 
ATOM   3976 C CB  . ILE A 1 537 ? 138.072 103.087 130.622 1.00 49.80  ? 537 ILE A CB  1 
ATOM   3977 C CG1 . ILE A 1 537 ? 137.336 101.911 129.981 1.00 49.80  ? 537 ILE A CG1 1 
ATOM   3978 C CG2 . ILE A 1 537 ? 139.519 102.732 130.914 1.00 49.80  ? 537 ILE A CG2 1 
ATOM   3979 C CD1 . ILE A 1 537 ? 137.903 101.493 128.647 1.00 49.80  ? 537 ILE A CD1 1 
ATOM   3980 N N   . PHE A 1 538 ? 137.514 105.964 131.892 1.00 48.94  ? 538 PHE A N   1 
ATOM   3981 C CA  . PHE A 1 538 ? 138.015 107.244 132.378 1.00 48.94  ? 538 PHE A CA  1 
ATOM   3982 C C   . PHE A 1 538 ? 137.557 107.509 133.805 1.00 48.94  ? 538 PHE A C   1 
ATOM   3983 O O   . PHE A 1 538 ? 138.336 108.001 134.634 1.00 48.94  ? 538 PHE A O   1 
ATOM   3984 C CB  . PHE A 1 538 ? 137.562 108.367 131.450 1.00 48.94  ? 538 PHE A CB  1 
ATOM   3985 C CG  . PHE A 1 538 ? 138.673 108.962 130.653 1.00 48.94  ? 538 PHE A CG  1 
ATOM   3986 C CD1 . PHE A 1 538 ? 139.199 108.278 129.575 1.00 48.94  ? 538 PHE A CD1 1 
ATOM   3987 C CD2 . PHE A 1 538 ? 139.211 110.188 130.989 1.00 48.94  ? 538 PHE A CD2 1 
ATOM   3988 C CE1 . PHE A 1 538 ? 140.227 108.812 128.839 1.00 48.94  ? 538 PHE A CE1 1 
ATOM   3989 C CE2 . PHE A 1 538 ? 140.244 110.724 130.254 1.00 48.94  ? 538 PHE A CE2 1 
ATOM   3990 C CZ  . PHE A 1 538 ? 140.753 110.031 129.179 1.00 48.94  ? 538 PHE A CZ  1 
ATOM   3991 N N   . ILE A 1 539 ? 136.296 107.185 134.109 1.00 55.16  ? 539 ILE A N   1 
ATOM   3992 C CA  . ILE A 1 539 ? 135.788 107.400 135.461 1.00 55.16  ? 539 ILE A CA  1 
ATOM   3993 C C   . ILE A 1 539 ? 136.581 106.574 136.465 1.00 55.16  ? 539 ILE A C   1 
ATOM   3994 O O   . ILE A 1 539 ? 137.005 107.080 137.513 1.00 55.16  ? 539 ILE A O   1 
ATOM   3995 C CB  . ILE A 1 539 ? 134.284 107.080 135.524 1.00 55.16  ? 539 ILE A CB  1 
ATOM   3996 C CG1 . ILE A 1 539 ? 133.465 108.272 135.028 1.00 55.16  ? 539 ILE A CG1 1 
ATOM   3997 C CG2 . ILE A 1 539 ? 133.868 106.710 136.932 1.00 55.16  ? 539 ILE A CG2 1 
ATOM   3998 C CD1 . ILE A 1 539 ? 132.003 107.992 134.934 1.00 55.16  ? 539 ILE A CD1 1 
ATOM   3999 N N   . VAL A 1 540 ? 136.832 105.305 136.141 1.00 59.80  ? 540 VAL A N   1 
ATOM   4000 C CA  . VAL A 1 540 ? 137.575 104.440 137.051 1.00 59.80  ? 540 VAL A CA  1 
ATOM   4001 C C   . VAL A 1 540 ? 139.018 104.912 137.188 1.00 59.80  ? 540 VAL A C   1 
ATOM   4002 O O   . VAL A 1 540 ? 139.580 104.919 138.291 1.00 59.80  ? 540 VAL A O   1 
ATOM   4003 C CB  . VAL A 1 540 ? 137.483 102.976 136.587 1.00 59.80  ? 540 VAL A CB  1 
ATOM   4004 C CG1 . VAL A 1 540 ? 138.468 102.108 137.356 1.00 59.80  ? 540 VAL A CG1 1 
ATOM   4005 C CG2 . VAL A 1 540 ? 136.059 102.467 136.780 1.00 59.80  ? 540 VAL A CG2 1 
ATOM   4006 N N   . LEU A 1 541 ? 139.636 105.333 136.082 1.00 58.72  ? 541 LEU A N   1 
ATOM   4007 C CA  . LEU A 1 541 ? 141.041 105.722 136.126 1.00 58.72  ? 541 LEU A CA  1 
ATOM   4008 C C   . LEU A 1 541 ? 141.250 106.996 136.936 1.00 58.72  ? 541 LEU A C   1 
ATOM   4009 O O   . LEU A 1 541 ? 142.146 107.053 137.786 1.00 58.72  ? 541 LEU A O   1 
ATOM   4010 C CB  . LEU A 1 541 ? 141.577 105.891 134.706 1.00 58.72  ? 541 LEU A CB  1 
ATOM   4011 C CG  . LEU A 1 541 ? 142.368 104.695 134.179 1.00 58.72  ? 541 LEU A CG  1 
ATOM   4012 C CD1 . LEU A 1 541 ? 142.733 104.891 132.714 1.00 58.72  ? 541 LEU A CD1 1 
ATOM   4013 C CD2 . LEU A 1 541 ? 143.607 104.469 135.033 1.00 58.72  ? 541 LEU A CD2 1 
ATOM   4014 N N   . LEU A 1 542 ? 140.442 108.031 136.691 1.00 60.15  ? 542 LEU A N   1 
ATOM   4015 C CA  . LEU A 1 542 ? 140.585 109.253 137.476 1.00 60.15  ? 542 LEU A CA  1 
ATOM   4016 C C   . LEU A 1 542 ? 140.050 109.093 138.895 1.00 60.15  ? 542 LEU A C   1 
ATOM   4017 O O   . LEU A 1 542 ? 140.424 109.870 139.780 1.00 60.15  ? 542 LEU A O   1 
ATOM   4018 C CB  . LEU A 1 542 ? 139.926 110.445 136.770 1.00 60.15  ? 542 LEU A CB  1 
ATOM   4019 C CG  . LEU A 1 542 ? 140.526 111.059 135.491 1.00 60.15  ? 542 LEU A CG  1 
ATOM   4020 C CD1 . LEU A 1 542 ? 141.926 111.584 135.804 1.00 60.15  ? 542 LEU A CD1 1 
ATOM   4021 C CD2 . LEU A 1 542 ? 140.559 110.122 134.286 1.00 60.15  ? 542 LEU A CD2 1 
ATOM   4022 N N   . SER A 1 543 ? 139.195 108.106 139.145 1.00 66.83  ? 543 SER A N   1 
ATOM   4023 C CA  . SER A 1 543 ? 138.748 107.868 140.517 1.00 66.83  ? 543 SER A CA  1 
ATOM   4024 C C   . SER A 1 543 ? 139.869 107.222 141.327 1.00 66.83  ? 543 SER A C   1 
ATOM   4025 O O   . SER A 1 543 ? 139.900 107.314 142.554 1.00 66.83  ? 543 SER A O   1 
ATOM   4026 C CB  . SER A 1 543 ? 137.504 106.980 140.551 1.00 66.83  ? 543 SER A CB  1 
ATOM   4027 O OG  . SER A 1 543 ? 137.752 105.737 139.927 1.00 66.83  ? 543 SER A OG  1 
ATOM   4028 O OXT . SER A 1 543 ? 140.772 106.594 140.772 1.00 66.83  ? 543 SER A OXT 1 
ATOM   4029 N N   . MET B 1 1   ? 113.039 81.209  137.003 1.00 86.93  ? 1   MET B N   1 
ATOM   4030 C CA  . MET B 1 1   ? 111.630 81.577  136.947 1.00 86.93  ? 1   MET B CA  1 
ATOM   4031 C C   . MET B 1 1   ? 111.432 83.000  137.457 1.00 86.93  ? 1   MET B C   1 
ATOM   4032 O O   . MET B 1 1   ? 110.576 83.735  136.968 1.00 86.93  ? 1   MET B O   1 
ATOM   4033 C CB  . MET B 1 1   ? 110.786 80.596  137.761 1.00 86.93  ? 1   MET B CB  1 
ATOM   4034 C CG  . MET B 1 1   ? 110.724 79.198  137.168 1.00 86.93  ? 1   MET B CG  1 
ATOM   4035 S SD  . MET B 1 1   ? 110.816 79.202  135.368 1.00 86.93  ? 1   MET B SD  1 
ATOM   4036 C CE  . MET B 1 1   ? 109.662 77.891  134.969 1.00 86.93  ? 1   MET B CE  1 
ATOM   4037 N N   . ASN B 1 2   ? 112.226 83.373  138.461 1.00 76.24  ? 2   ASN B N   1 
ATOM   4038 C CA  . ASN B 1 2   ? 112.203 84.738  138.970 1.00 76.24  ? 2   ASN B CA  1 
ATOM   4039 C C   . ASN B 1 2   ? 113.124 85.625  138.138 1.00 76.24  ? 2   ASN B C   1 
ATOM   4040 O O   . ASN B 1 2   ? 112.829 86.810  137.944 1.00 76.24  ? 2   ASN B O   1 
ATOM   4041 C CB  . ASN B 1 2   ? 112.575 84.705  140.468 1.00 76.24  ? 2   ASN B CB  1 
ATOM   4042 C CG  . ASN B 1 2   ? 112.709 86.092  141.134 1.00 76.24  ? 2   ASN B CG  1 
ATOM   4043 O OD1 . ASN B 1 2   ? 113.131 87.084  140.545 1.00 76.24  ? 2   ASN B OD1 1 
ATOM   4044 N ND2 . ASN B 1 2   ? 112.331 86.140  142.406 1.00 76.24  ? 2   ASN B ND2 1 
ATOM   4045 N N   . ALA B 1 3   ? 114.198 85.052  137.588 1.00 67.30  ? 3   ALA B N   1 
ATOM   4046 C CA  . ALA B 1 3   ? 115.181 85.840  136.850 1.00 67.30  ? 3   ALA B CA  1 
ATOM   4047 C C   . ALA B 1 3   ? 114.583 86.455  135.590 1.00 67.30  ? 3   ALA B C   1 
ATOM   4048 O O   . ALA B 1 3   ? 114.922 87.588  135.229 1.00 67.30  ? 3   ALA B O   1 
ATOM   4049 C CB  . ALA B 1 3   ? 116.391 84.976  136.500 1.00 67.30  ? 3   ALA B CB  1 
ATOM   4050 N N   . ILE B 1 4   ? 113.708 85.724  134.898 1.00 61.33  ? 4   ILE B N   1 
ATOM   4051 C CA  . ILE B 1 4   ? 113.083 86.267  133.695 1.00 61.33  ? 4   ILE B CA  1 
ATOM   4052 C C   . ILE B 1 4   ? 112.191 87.455  134.041 1.00 61.33  ? 4   ILE B C   1 
ATOM   4053 O O   . ILE B 1 4   ? 112.200 88.479  133.345 1.00 61.33  ? 4   ILE B O   1 
ATOM   4054 C CB  . ILE B 1 4   ? 112.314 85.162  132.944 1.00 61.33  ? 4   ILE B CB  1 
ATOM   4055 C CG1 . ILE B 1 4   ? 111.487 85.760  131.805 1.00 61.33  ? 4   ILE B CG1 1 
ATOM   4056 C CG2 . ILE B 1 4   ? 111.449 84.349  133.897 1.00 61.33  ? 4   ILE B CG2 1 
ATOM   4057 C CD1 . ILE B 1 4   ? 112.306 86.120  130.587 1.00 61.33  ? 4   ILE B CD1 1 
ATOM   4058 N N   . GLY B 1 5   ? 111.422 87.347  135.127 1.00 59.92  ? 5   GLY B N   1 
ATOM   4059 C CA  . GLY B 1 5   ? 110.623 88.477  135.570 1.00 59.92  ? 5   GLY B CA  1 
ATOM   4060 C C   . GLY B 1 5   ? 111.474 89.661  135.986 1.00 59.92  ? 5   GLY B C   1 
ATOM   4061 O O   . GLY B 1 5   ? 111.128 90.814  135.712 1.00 59.92  ? 5   GLY B O   1 
ATOM   4062 N N   . ASN B 1 6   ? 112.599 89.392  136.655 1.00 59.02  ? 6   ASN B N   1 
ATOM   4063 C CA  . ASN B 1 6   ? 113.516 90.461  137.036 1.00 59.02  ? 6   ASN B CA  1 
ATOM   4064 C C   . ASN B 1 6   ? 114.080 91.165  135.811 1.00 59.02  ? 6   ASN B C   1 
ATOM   4065 O O   . ASN B 1 6   ? 114.173 92.395  135.784 1.00 59.02  ? 6   ASN B O   1 
ATOM   4066 C CB  . ASN B 1 6   ? 114.647 89.901  137.898 1.00 59.02  ? 6   ASN B CB  1 
ATOM   4067 C CG  . ASN B 1 6   ? 114.506 90.273  139.360 1.00 59.02  ? 6   ASN B CG  1 
ATOM   4068 O OD1 . ASN B 1 6   ? 114.548 91.449  139.720 1.00 59.02  ? 6   ASN B OD1 1 
ATOM   4069 N ND2 . ASN B 1 6   ? 114.339 89.269  140.213 1.00 59.02  ? 6   ASN B ND2 1 
ATOM   4070 N N   . PHE B 1 7   ? 114.452 90.399  134.784 1.00 51.73  ? 7   PHE B N   1 
ATOM   4071 C CA  . PHE B 1 7   ? 114.936 90.993  133.543 1.00 51.73  ? 7   PHE B CA  1 
ATOM   4072 C C   . PHE B 1 7   ? 113.864 91.850  132.882 1.00 51.73  ? 7   PHE B C   1 
ATOM   4073 O O   . PHE B 1 7   ? 114.132 92.987  132.464 1.00 51.73  ? 7   PHE B O   1 
ATOM   4074 C CB  . PHE B 1 7   ? 115.400 89.882  132.600 1.00 51.73  ? 7   PHE B CB  1 
ATOM   4075 C CG  . PHE B 1 7   ? 115.965 90.373  131.301 1.00 51.73  ? 7   PHE B CG  1 
ATOM   4076 C CD1 . PHE B 1 7   ? 117.063 91.211  131.278 1.00 51.73  ? 7   PHE B CD1 1 
ATOM   4077 C CD2 . PHE B 1 7   ? 115.406 89.975  130.100 1.00 51.73  ? 7   PHE B CD2 1 
ATOM   4078 C CE1 . PHE B 1 7   ? 117.587 91.656  130.081 1.00 51.73  ? 7   PHE B CE1 1 
ATOM   4079 C CE2 . PHE B 1 7   ? 115.924 90.414  128.899 1.00 51.73  ? 7   PHE B CE2 1 
ATOM   4080 C CZ  . PHE B 1 7   ? 117.015 91.255  128.889 1.00 51.73  ? 7   PHE B CZ  1 
ATOM   4081 N N   . LEU B 1 8   ? 112.635 91.329  132.808 1.00 49.45  ? 8   LEU B N   1 
ATOM   4082 C CA  . LEU B 1 8   ? 111.554 92.054  132.149 1.00 49.45  ? 8   LEU B CA  1 
ATOM   4083 C C   . LEU B 1 8   ? 111.227 93.352  132.876 1.00 49.45  ? 8   LEU B C   1 
ATOM   4084 O O   . LEU B 1 8   ? 110.994 94.384  132.236 1.00 49.45  ? 8   LEU B O   1 
ATOM   4085 C CB  . LEU B 1 8   ? 110.314 91.167  132.050 1.00 49.45  ? 8   LEU B CB  1 
ATOM   4086 C CG  . LEU B 1 8   ? 110.391 90.006  131.055 1.00 49.45  ? 8   LEU B CG  1 
ATOM   4087 C CD1 . LEU B 1 8   ? 109.310 88.978  131.347 1.00 49.45  ? 8   LEU B CD1 1 
ATOM   4088 C CD2 . LEU B 1 8   ? 110.294 90.498  129.623 1.00 49.45  ? 8   LEU B CD2 1 
ATOM   4089 N N   . VAL B 1 9   ? 111.204 93.326  134.210 1.00 50.31  ? 9   VAL B N   1 
ATOM   4090 C CA  . VAL B 1 9   ? 110.905 94.550  134.945 1.00 50.31  ? 9   VAL B CA  1 
ATOM   4091 C C   . VAL B 1 9   ? 112.107 95.494  134.942 1.00 50.31  ? 9   VAL B C   1 
ATOM   4092 O O   . VAL B 1 9   ? 111.939 96.717  135.023 1.00 50.31  ? 9   VAL B O   1 
ATOM   4093 C CB  . VAL B 1 9   ? 110.429 94.228  136.374 1.00 50.31  ? 9   VAL B CB  1 
ATOM   4094 C CG1 . VAL B 1 9   ? 111.551 93.634  137.212 1.00 50.31  ? 9   VAL B CG1 1 
ATOM   4095 C CG2 . VAL B 1 9   ? 109.844 95.467  137.044 1.00 50.31  ? 9   VAL B CG2 1 
ATOM   4096 N N   . GLY B 1 10  ? 113.326 94.960  134.837 1.00 52.90  ? 10  GLY B N   1 
ATOM   4097 C CA  . GLY B 1 10  ? 114.496 95.816  134.765 1.00 52.90  ? 10  GLY B CA  1 
ATOM   4098 C C   . GLY B 1 10  ? 114.573 96.599  133.471 1.00 52.90  ? 10  GLY B C   1 
ATOM   4099 O O   . GLY B 1 10  ? 114.965 97.769  133.467 1.00 52.90  ? 10  GLY B O   1 
ATOM   4100 N N   . THR B 1 11  ? 114.205 95.970  132.353 1.00 49.51  ? 11  THR B N   1 
ATOM   4101 C CA  . THR B 1 11  ? 114.295 96.633  131.055 1.00 49.51  ? 11  THR B CA  1 
ATOM   4102 C C   . THR B 1 11  ? 112.904 96.871  130.483 1.00 49.51  ? 11  THR B C   1 
ATOM   4103 O O   . THR B 1 11  ? 112.326 95.965  129.864 1.00 49.51  ? 11  THR B O   1 
ATOM   4104 C CB  . THR B 1 11  ? 115.135 95.800  130.086 1.00 49.51  ? 11  THR B CB  1 
ATOM   4105 O OG1 . THR B 1 11  ? 114.354 94.708  129.591 1.00 49.51  ? 11  THR B OG1 1 
ATOM   4106 C CG2 . THR B 1 11  ? 116.340 95.250  130.797 1.00 49.51  ? 11  THR B CG2 1 
ATOM   4107 N N   . PRO B 1 12  ? 112.322 98.061  130.659 1.00 44.68  ? 12  PRO B N   1 
ATOM   4108 C CA  . PRO B 1 12  ? 110.984 98.306  130.103 1.00 44.68  ? 12  PRO B CA  1 
ATOM   4109 C C   . PRO B 1 12  ? 110.955 98.351  128.586 1.00 44.68  ? 12  PRO B C   1 
ATOM   4110 O O   . PRO B 1 12  ? 109.926 98.003  127.993 1.00 44.68  ? 12  PRO B O   1 
ATOM   4111 C CB  . PRO B 1 12  ? 110.594 99.659  130.714 1.00 44.68  ? 12  PRO B CB  1 
ATOM   4112 C CG  . PRO B 1 12  ? 111.495 99.813  131.910 1.00 44.68  ? 12  PRO B CG  1 
ATOM   4113 C CD  . PRO B 1 12  ? 112.783 99.190  131.481 1.00 44.68  ? 12  PRO B CD  1 
ATOM   4114 N N   . VAL B 1 13  ? 112.046 98.774  127.941 1.00 40.08  ? 13  VAL B N   1 
ATOM   4115 C CA  . VAL B 1 13  ? 112.058 98.885  126.483 1.00 40.08  ? 13  VAL B CA  1 
ATOM   4116 C C   . VAL B 1 13  ? 111.890 97.512  125.847 1.00 40.08  ? 13  VAL B C   1 
ATOM   4117 O O   . VAL B 1 13  ? 111.119 97.338  124.894 1.00 40.08  ? 13  VAL B O   1 
ATOM   4118 C CB  . VAL B 1 13  ? 113.350 99.570  126.005 1.00 40.08  ? 13  VAL B CB  1 
ATOM   4119 C CG1 . VAL B 1 13  ? 113.220 99.976  124.548 1.00 40.08  ? 13  VAL B CG1 1 
ATOM   4120 C CG2 . VAL B 1 13  ? 113.668 100.773 126.877 1.00 40.08  ? 13  VAL B CG2 1 
ATOM   4121 N N   . PHE B 1 14  ? 112.612 96.517  126.368 1.00 38.39  ? 14  PHE B N   1 
ATOM   4122 C CA  . PHE B 1 14  ? 112.503 95.161  125.841 1.00 38.39  ? 14  PHE B CA  1 
ATOM   4123 C C   . PHE B 1 14  ? 111.091 94.618  126.007 1.00 38.39  ? 14  PHE B C   1 
ATOM   4124 O O   . PHE B 1 14  ? 110.546 94.007  125.084 1.00 38.39  ? 14  PHE B O   1 
ATOM   4125 C CB  . PHE B 1 14  ? 113.513 94.247  126.531 1.00 38.39  ? 14  PHE B CB  1 
ATOM   4126 C CG  . PHE B 1 14  ? 113.441 92.817  126.086 1.00 38.39  ? 14  PHE B CG  1 
ATOM   4127 C CD1 . PHE B 1 14  ? 113.789 92.457  124.797 1.00 38.39  ? 14  PHE B CD1 1 
ATOM   4128 C CD2 . PHE B 1 14  ? 113.021 91.832  126.961 1.00 38.39  ? 14  PHE B CD2 1 
ATOM   4129 C CE1 . PHE B 1 14  ? 113.723 91.138  124.392 1.00 38.39  ? 14  PHE B CE1 1 
ATOM   4130 C CE2 . PHE B 1 14  ? 112.952 90.515  126.561 1.00 38.39  ? 14  PHE B CE2 1 
ATOM   4131 C CZ  . PHE B 1 14  ? 113.303 90.167  125.276 1.00 38.39  ? 14  PHE B CZ  1 
ATOM   4132 N N   . THR B 1 15  ? 110.474 94.849  127.168 1.00 35.62  ? 15  THR B N   1 
ATOM   4133 C CA  . THR B 1 15  ? 109.123 94.349  127.398 1.00 35.62  ? 15  THR B CA  1 
ATOM   4134 C C   . THR B 1 15  ? 108.117 95.013  126.464 1.00 35.62  ? 15  THR B C   1 
ATOM   4135 O O   . THR B 1 15  ? 107.291 94.331  125.842 1.00 35.62  ? 15  THR B O   1 
ATOM   4136 C CB  . THR B 1 15  ? 108.735 94.570  128.859 1.00 35.62  ? 15  THR B CB  1 
ATOM   4137 O OG1 . THR B 1 15  ? 109.411 93.613  129.681 1.00 35.62  ? 15  THR B OG1 1 
ATOM   4138 C CG2 . THR B 1 15  ? 107.242 94.401  129.050 1.00 35.62  ? 15  THR B CG2 1 
ATOM   4139 N N   . ILE B 1 16  ? 108.195 96.339  126.325 1.00 33.91  ? 16  ILE B N   1 
ATOM   4140 C CA  . ILE B 1 16  ? 107.237 97.061  125.492 1.00 33.91  ? 16  ILE B CA  1 
ATOM   4141 C C   . ILE B 1 16  ? 107.395 96.677  124.026 1.00 33.91  ? 16  ILE B C   1 
ATOM   4142 O O   . ILE B 1 16  ? 106.402 96.489  123.312 1.00 33.91  ? 16  ILE B O   1 
ATOM   4143 C CB  . ILE B 1 16  ? 107.377 98.581  125.703 1.00 33.91  ? 16  ILE B CB  1 
ATOM   4144 C CG1 . ILE B 1 16  ? 107.002 98.951  127.139 1.00 33.91  ? 16  ILE B CG1 1 
ATOM   4145 C CG2 . ILE B 1 16  ? 106.510 99.346  124.718 1.00 33.91  ? 16  ILE B CG2 1 
ATOM   4146 C CD1 . ILE B 1 16  ? 106.850 100.440 127.372 1.00 33.91  ? 16  ILE B CD1 1 
ATOM   4147 N N   . PHE B 1 17  ? 108.631 96.540  123.549 1.00 55.03  ? 17  PHE B N   1 
ATOM   4148 C CA  . PHE B 1 17  ? 108.843 96.227  122.143 1.00 55.03  ? 17  PHE B CA  1 
ATOM   4149 C C   . PHE B 1 17  ? 108.886 94.729  121.859 1.00 55.03  ? 17  PHE B C   1 
ATOM   4150 O O   . PHE B 1 17  ? 109.065 94.341  120.700 1.00 55.03  ? 17  PHE B O   1 
ATOM   4151 C CB  . PHE B 1 17  ? 110.123 96.899  121.641 1.00 55.03  ? 17  PHE B CB  1 
ATOM   4152 C CG  . PHE B 1 17  ? 109.922 98.328  121.216 1.00 55.03  ? 17  PHE B CG  1 
ATOM   4153 C CD1 . PHE B 1 17  ? 109.976 99.354  122.143 1.00 55.03  ? 17  PHE B CD1 1 
ATOM   4154 C CD2 . PHE B 1 17  ? 109.654 98.640  119.895 1.00 55.03  ? 17  PHE B CD2 1 
ATOM   4155 C CE1 . PHE B 1 17  ? 109.782 100.666 121.757 1.00 55.03  ? 17  PHE B CE1 1 
ATOM   4156 C CE2 . PHE B 1 17  ? 109.459 99.952  119.504 1.00 55.03  ? 17  PHE B CE2 1 
ATOM   4157 C CZ  . PHE B 1 17  ? 109.523 100.964 120.437 1.00 55.03  ? 17  PHE B CZ  1 
ATOM   4158 N N   . ILE B 1 18  ? 108.732 93.884  122.877 1.00 35.91  ? 18  ILE B N   1 
ATOM   4159 C CA  . ILE B 1 18  ? 108.491 92.464  122.652 1.00 35.91  ? 18  ILE B CA  1 
ATOM   4160 C C   . ILE B 1 18  ? 107.016 92.111  122.810 1.00 35.91  ? 18  ILE B C   1 
ATOM   4161 O O   . ILE B 1 18  ? 106.593 91.046  122.334 1.00 35.91  ? 18  ILE B O   1 
ATOM   4162 C CB  . ILE B 1 18  ? 109.358 91.592  123.586 1.00 35.91  ? 18  ILE B CB  1 
ATOM   4163 C CG1 . ILE B 1 18  ? 109.707 90.270  122.907 1.00 35.91  ? 18  ILE B CG1 1 
ATOM   4164 C CG2 . ILE B 1 18  ? 108.654 91.334  124.908 1.00 35.91  ? 18  ILE B CG2 1 
ATOM   4165 C CD1 . ILE B 1 18  ? 110.466 90.436  121.619 1.00 35.91  ? 18  ILE B CD1 1 
ATOM   4166 N N   . CYS B 1 19  ? 106.226 92.962  123.458 1.00 36.82  ? 19  CYS B N   1 
ATOM   4167 C CA  . CYS B 1 19  ? 104.778 92.822  123.439 1.00 36.82  ? 19  CYS B CA  1 
ATOM   4168 C C   . CYS B 1 19  ? 104.161 93.450  122.198 1.00 36.82  ? 19  CYS B C   1 
ATOM   4169 O O   . CYS B 1 19  ? 102.944 93.360  122.011 1.00 36.82  ? 19  CYS B O   1 
ATOM   4170 C CB  . CYS B 1 19  ? 104.165 93.443  124.697 1.00 36.82  ? 19  CYS B CB  1 
ATOM   4171 N N   . LEU B 1 20  ? 104.974 94.084  121.353 1.00 31.92  ? 20  LEU B N   1 
ATOM   4172 C CA  . LEU B 1 20  ? 104.511 94.689  120.114 1.00 31.92  ? 20  LEU B CA  1 
ATOM   4173 C C   . LEU B 1 20  ? 104.935 93.909  118.877 1.00 31.92  ? 20  LEU B C   1 
ATOM   4174 O O   . LEU B 1 20  ? 104.345 94.101  117.809 1.00 31.92  ? 20  LEU B O   1 
ATOM   4175 C CB  . LEU B 1 20  ? 105.026 96.134  120.022 1.00 31.92  ? 20  LEU B CB  1 
ATOM   4176 C CG  . LEU B 1 20  ? 104.403 97.146  119.060 1.00 31.92  ? 20  LEU B CG  1 
ATOM   4177 C CD1 . LEU B 1 20  ? 104.440 98.524  119.690 1.00 31.92  ? 20  LEU B CD1 1 
ATOM   4178 C CD2 . LEU B 1 20  ? 105.140 97.173  117.736 1.00 31.92  ? 20  LEU B CD2 1 
ATOM   4179 N N   . ALA B 1 21  ? 105.920 93.020  118.998 1.00 36.15  ? 21  ALA B N   1 
ATOM   4180 C CA  . ALA B 1 21  ? 106.405 92.248  117.861 1.00 36.15  ? 21  ALA B CA  1 
ATOM   4181 C C   . ALA B 1 21  ? 105.553 91.011  117.607 1.00 36.15  ? 21  ALA B C   1 
ATOM   4182 O O   . ALA B 1 21  ? 105.100 90.788  116.480 1.00 36.15  ? 21  ALA B O   1 
ATOM   4183 C CB  . ALA B 1 21  ? 107.866 91.844  118.084 1.00 36.15  ? 21  ALA B CB  1 
ATOM   4184 N N   . LEU B 1 22  ? 105.325 90.200  118.642 1.00 38.42  ? 22  LEU B N   1 
ATOM   4185 C CA  . LEU B 1 22  ? 104.521 88.994  118.491 1.00 38.42  ? 22  LEU B CA  1 
ATOM   4186 C C   . LEU B 1 22  ? 103.053 89.305  118.229 1.00 38.42  ? 22  LEU B C   1 
ATOM   4187 O O   . LEU B 1 22  ? 102.339 88.458  117.677 1.00 38.42  ? 22  LEU B O   1 
ATOM   4188 C CB  . LEU B 1 22  ? 104.653 88.125  119.742 1.00 38.42  ? 22  LEU B CB  1 
ATOM   4189 C CG  . LEU B 1 22  ? 106.042 87.555  120.030 1.00 38.42  ? 22  LEU B CG  1 
ATOM   4190 C CD1 . LEU B 1 22  ? 105.980 86.539  121.157 1.00 38.42  ? 22  LEU B CD1 1 
ATOM   4191 C CD2 . LEU B 1 22  ? 106.650 86.937  118.782 1.00 38.42  ? 22  LEU B CD2 1 
ATOM   4192 N N   . GLY B 1 23  ? 102.592 90.495  118.617 1.00 40.41  ? 23  GLY B N   1 
ATOM   4193 C CA  . GLY B 1 23  ? 101.197 90.845  118.410 1.00 40.41  ? 23  GLY B CA  1 
ATOM   4194 C C   . GLY B 1 23  ? 100.814 90.912  116.945 1.00 40.41  ? 23  GLY B C   1 
ATOM   4195 O O   . GLY B 1 23  ? 99.736  90.460  116.556 1.00 40.41  ? 23  GLY B O   1 
ATOM   4196 N N   . TYR B 1 24  ? 101.689 91.483  116.112 1.00 37.68  ? 24  TYR B N   1 
ATOM   4197 C CA  . TYR B 1 24  ? 101.401 91.561  114.684 1.00 37.68  ? 24  TYR B CA  1 
ATOM   4198 C C   . TYR B 1 24  ? 101.344 90.177  114.051 1.00 37.68  ? 24  TYR B C   1 
ATOM   4199 O O   . TYR B 1 24  ? 100.483 89.912  113.204 1.00 37.68  ? 24  TYR B O   1 
ATOM   4200 C CB  . TYR B 1 24  ? 102.438 92.436  113.982 1.00 37.68  ? 24  TYR B CB  1 
ATOM   4201 C CG  . TYR B 1 24  ? 102.174 93.917  114.122 1.00 37.68  ? 24  TYR B CG  1 
ATOM   4202 C CD1 . TYR B 1 24  ? 102.446 94.581  115.309 1.00 37.68  ? 24  TYR B CD1 1 
ATOM   4203 C CD2 . TYR B 1 24  ? 101.647 94.649  113.070 1.00 37.68  ? 24  TYR B CD2 1 
ATOM   4204 C CE1 . TYR B 1 24  ? 102.205 95.933  115.442 1.00 37.68  ? 24  TYR B CE1 1 
ATOM   4205 C CE2 . TYR B 1 24  ? 101.401 96.001  113.193 1.00 37.68  ? 24  TYR B CE2 1 
ATOM   4206 C CZ  . TYR B 1 24  ? 101.682 96.637  114.381 1.00 37.68  ? 24  TYR B CZ  1 
ATOM   4207 O OH  . TYR B 1 24  ? 101.439 97.984  114.509 1.00 37.68  ? 24  TYR B OH  1 
ATOM   4208 N N   . LEU B 1 25  ? 102.248 89.279  114.449 1.00 43.99  ? 25  LEU B N   1 
ATOM   4209 C CA  . LEU B 1 25  ? 102.201 87.909  113.945 1.00 43.99  ? 25  LEU B CA  1 
ATOM   4210 C C   . LEU B 1 25  ? 100.919 87.206  114.373 1.00 43.99  ? 25  LEU B C   1 
ATOM   4211 O O   . LEU B 1 25  ? 100.285 86.507  113.570 1.00 43.99  ? 25  LEU B O   1 
ATOM   4212 C CB  . LEU B 1 25  ? 103.422 87.129  114.427 1.00 43.99  ? 25  LEU B CB  1 
ATOM   4213 C CG  . LEU B 1 25  ? 104.531 86.883  113.404 1.00 43.99  ? 25  LEU B CG  1 
ATOM   4214 C CD1 . LEU B 1 25  ? 104.938 88.180  112.726 1.00 43.99  ? 25  LEU B CD1 1 
ATOM   4215 C CD2 . LEU B 1 25  ? 105.723 86.222  114.071 1.00 43.99  ? 25  LEU B CD2 1 
ATOM   4216 N N   . LEU B 1 26  ? 100.516 87.387  115.634 1.00 42.46  ? 26  LEU B N   1 
ATOM   4217 C CA  . LEU B 1 26  ? 99.280  86.770  116.103 1.00 42.46  ? 26  LEU B CA  1 
ATOM   4218 C C   . LEU B 1 26  ? 98.073  87.327  115.361 1.00 42.46  ? 26  LEU B C   1 
ATOM   4219 O O   . LEU B 1 26  ? 97.133  86.589  115.048 1.00 42.46  ? 26  LEU B O   1 
ATOM   4220 C CB  . LEU B 1 26  ? 99.126  86.974  117.607 1.00 42.46  ? 26  LEU B CB  1 
ATOM   4221 C CG  . LEU B 1 26  ? 98.614  85.752  118.369 1.00 42.46  ? 26  LEU B CG  1 
ATOM   4222 C CD1 . LEU B 1 26  ? 99.585  84.589  118.233 1.00 42.46  ? 26  LEU B CD1 1 
ATOM   4223 C CD2 . LEU B 1 26  ? 98.382  86.095  119.827 1.00 42.46  ? 26  LEU B CD2 1 
ATOM   4224 N N   . GLY B 1 27  ? 98.081  88.629  115.077 1.00 48.43  ? 27  GLY B N   1 
ATOM   4225 C CA  . GLY B 1 27  ? 96.993  89.220  114.319 1.00 48.43  ? 27  GLY B CA  1 
ATOM   4226 C C   . GLY B 1 27  ? 96.947  88.734  112.884 1.00 48.43  ? 27  GLY B C   1 
ATOM   4227 O O   . GLY B 1 27  ? 95.867  88.546  112.317 1.00 48.43  ? 27  GLY B O   1 
ATOM   4228 N N   . LYS B 1 28  ? 98.112  88.526  112.274 1.00 51.98  ? 28  LYS B N   1 
ATOM   4229 C CA  . LYS B 1 28  ? 98.169  88.030  110.906 1.00 51.98  ? 28  LYS B CA  1 
ATOM   4230 C C   . LYS B 1 28  ? 97.993  86.521  110.809 1.00 51.98  ? 28  LYS B C   1 
ATOM   4231 O O   . LYS B 1 28  ? 97.920  85.998  109.692 1.00 51.98  ? 28  LYS B O   1 
ATOM   4232 C CB  . LYS B 1 28  ? 99.486  88.443  110.245 1.00 51.98  ? 28  LYS B CB  1 
ATOM   4233 C CG  . LYS B 1 28  ? 99.635  89.942  110.056 1.00 51.98  ? 28  LYS B CG  1 
ATOM   4234 C CD  . LYS B 1 28  ? 101.050 90.304  109.645 1.00 51.98  ? 28  LYS B CD  1 
ATOM   4235 C CE  . LYS B 1 28  ? 101.373 89.758  108.265 1.00 51.98  ? 28  LYS B CE  1 
ATOM   4236 N NZ  . LYS B 1 28  ? 100.426 90.260  107.232 1.00 51.98  ? 28  LYS B NZ  1 
ATOM   4237 N N   . LEU B 1 29  ? 97.933  85.811  111.934 1.00 61.46  ? 29  LEU B N   1 
ATOM   4238 C CA  . LEU B 1 29  ? 97.601  84.393  111.893 1.00 61.46  ? 29  LEU B CA  1 
ATOM   4239 C C   . LEU B 1 29  ? 96.176  84.192  111.393 1.00 61.46  ? 29  LEU B C   1 
ATOM   4240 O O   . LEU B 1 29  ? 95.257  84.921  111.774 1.00 61.46  ? 29  LEU B O   1 
ATOM   4241 C CB  . LEU B 1 29  ? 97.759  83.765  113.276 1.00 61.46  ? 29  LEU B CB  1 
ATOM   4242 C CG  . LEU B 1 29  ? 97.871  82.241  113.289 1.00 61.46  ? 29  LEU B CG  1 
ATOM   4243 C CD1 . LEU B 1 29  ? 99.113  81.788  112.540 1.00 61.46  ? 29  LEU B CD1 1 
ATOM   4244 C CD2 . LEU B 1 29  ? 97.872  81.711  114.713 1.00 61.46  ? 29  LEU B CD2 1 
ATOM   4245 N N   . LYS B 1 30  ? 95.994  83.189  110.533 1.00 84.55  ? 30  LYS B N   1 
ATOM   4246 C CA  . LYS B 1 30  ? 94.692  82.864  109.958 1.00 84.55  ? 30  LYS B CA  1 
ATOM   4247 C C   . LYS B 1 30  ? 94.118  81.651  110.682 1.00 84.55  ? 30  LYS B C   1 
ATOM   4248 O O   . LYS B 1 30  ? 94.604  80.529  110.509 1.00 84.55  ? 30  LYS B O   1 
ATOM   4249 C CB  . LYS B 1 30  ? 94.806  82.595  108.458 1.00 84.55  ? 30  LYS B CB  1 
ATOM   4250 C CG  . LYS B 1 30  ? 94.623  83.824  107.587 1.00 84.55  ? 30  LYS B CG  1 
ATOM   4251 C CD  . LYS B 1 30  ? 95.136  83.583  106.180 1.00 84.55  ? 30  LYS B CD  1 
ATOM   4252 C CE  . LYS B 1 30  ? 96.406  84.369  105.909 1.00 84.55  ? 30  LYS B CE  1 
ATOM   4253 N NZ  . LYS B 1 30  ? 97.287  83.675  104.928 1.00 84.55  ? 30  LYS B NZ  1 
ATOM   4254 N N   . ILE B 1 31  ? 93.083  81.877  111.487 1.00 92.93  ? 31  ILE B N   1 
ATOM   4255 C CA  . ILE B 1 31  ? 92.380  80.815  112.198 1.00 92.93  ? 31  ILE B CA  1 
ATOM   4256 C C   . ILE B 1 31  ? 90.931  80.822  111.735 1.00 92.93  ? 31  ILE B C   1 
ATOM   4257 O O   . ILE B 1 31  ? 90.239  81.840  111.866 1.00 92.93  ? 31  ILE B O   1 
ATOM   4258 C CB  . ILE B 1 31  ? 92.466  80.990  113.723 1.00 92.93  ? 31  ILE B CB  1 
ATOM   4259 C CG1 . ILE B 1 31  ? 93.876  81.417  114.136 1.00 92.93  ? 31  ILE B CG1 1 
ATOM   4260 C CG2 . ILE B 1 31  ? 92.066  79.705  114.430 1.00 92.93  ? 31  ILE B CG2 1 
ATOM   4261 C CD1 . ILE B 1 31  ? 94.055  81.570  115.630 1.00 92.93  ? 31  ILE B CD1 1 
ATOM   4262 N N   . GLY B 1 32  ? 90.471  79.692  111.213 1.00 106.25 ? 32  GLY B N   1 
ATOM   4263 C CA  . GLY B 1 32  ? 89.103  79.605  110.728 1.00 106.25 ? 32  GLY B CA  1 
ATOM   4264 C C   . GLY B 1 32  ? 88.882  80.542  109.555 1.00 106.25 ? 32  GLY B C   1 
ATOM   4265 O O   . GLY B 1 32  ? 89.582  80.478  108.537 1.00 106.25 ? 32  GLY B O   1 
ATOM   4266 N N   . SER B 1 33  ? 87.895  81.428  109.690 1.00 107.53 ? 33  SER B N   1 
ATOM   4267 C CA  . SER B 1 33  ? 87.581  82.411  108.660 1.00 107.53 ? 33  SER B CA  1 
ATOM   4268 C C   . SER B 1 33  ? 87.774  83.844  109.138 1.00 107.53 ? 33  SER B C   1 
ATOM   4269 O O   . SER B 1 33  ? 87.405  84.780  108.420 1.00 107.53 ? 33  SER B O   1 
ATOM   4270 C CB  . SER B 1 33  ? 86.145  82.218  108.161 1.00 107.53 ? 33  SER B CB  1 
ATOM   4271 O OG  . SER B 1 33  ? 85.207  82.621  109.143 1.00 107.53 ? 33  SER B OG  1 
ATOM   4272 N N   . PHE B 1 34  ? 88.338  84.043  110.326 1.00 85.62  ? 34  PHE B N   1 
ATOM   4273 C CA  . PHE B 1 34  ? 88.515  85.368  110.903 1.00 85.62  ? 34  PHE B CA  1 
ATOM   4274 C C   . PHE B 1 34  ? 89.969  85.577  111.298 1.00 85.62  ? 34  PHE B C   1 
ATOM   4275 O O   . PHE B 1 34  ? 90.652  84.639  111.721 1.00 85.62  ? 34  PHE B O   1 
ATOM   4276 C CB  . PHE B 1 34  ? 87.599  85.564  112.118 1.00 85.62  ? 34  PHE B CB  1 
ATOM   4277 C CG  . PHE B 1 34  ? 88.150  84.996  113.396 1.00 85.62  ? 34  PHE B CG  1 
ATOM   4278 C CD1 . PHE B 1 34  ? 88.207  83.626  113.593 1.00 85.62  ? 34  PHE B CD1 1 
ATOM   4279 C CD2 . PHE B 1 34  ? 88.603  85.831  114.404 1.00 85.62  ? 34  PHE B CD2 1 
ATOM   4280 C CE1 . PHE B 1 34  ? 88.712  83.100  114.768 1.00 85.62  ? 34  PHE B CE1 1 
ATOM   4281 C CE2 . PHE B 1 34  ? 89.108  85.311  115.582 1.00 85.62  ? 34  PHE B CE2 1 
ATOM   4282 C CZ  . PHE B 1 34  ? 89.162  83.943  115.764 1.00 85.62  ? 34  PHE B CZ  1 
ATOM   4283 N N   . THR B 1 35  ? 90.441  86.811  111.142 1.00 67.53  ? 35  THR B N   1 
ATOM   4284 C CA  . THR B 1 35  ? 91.775  87.212  111.567 1.00 67.53  ? 35  THR B CA  1 
ATOM   4285 C C   . THR B 1 35  ? 91.646  88.126  112.777 1.00 67.53  ? 35  THR B C   1 
ATOM   4286 O O   . THR B 1 35  ? 90.835  89.058  112.769 1.00 67.53  ? 35  THR B O   1 
ATOM   4287 C CB  . THR B 1 35  ? 92.526  87.921  110.438 1.00 67.53  ? 35  THR B CB  1 
ATOM   4288 O OG1 . THR B 1 35  ? 91.881  89.165  110.138 1.00 67.53  ? 35  THR B OG1 1 
ATOM   4289 C CG2 . THR B 1 35  ? 92.547  87.054  109.189 1.00 67.53  ? 35  THR B CG2 1 
ATOM   4290 N N   . LEU B 1 36  ? 92.440  87.850  113.816 1.00 48.60  ? 36  LEU B N   1 
ATOM   4291 C CA  . LEU B 1 36  ? 92.296  88.574  115.076 1.00 48.60  ? 36  LEU B CA  1 
ATOM   4292 C C   . LEU B 1 36  ? 92.600  90.057  114.911 1.00 48.60  ? 36  LEU B C   1 
ATOM   4293 O O   . LEU B 1 36  ? 91.892  90.908  115.462 1.00 48.60  ? 36  LEU B O   1 
ATOM   4294 C CB  . LEU B 1 36  ? 93.204  87.961  116.139 1.00 48.60  ? 36  LEU B CB  1 
ATOM   4295 C CG  . LEU B 1 36  ? 92.822  86.562  116.617 1.00 48.60  ? 36  LEU B CG  1 
ATOM   4296 C CD1 . LEU B 1 36  ? 93.718  85.519  115.975 1.00 48.60  ? 36  LEU B CD1 1 
ATOM   4297 C CD2 . LEU B 1 36  ? 92.892  86.483  118.129 1.00 48.60  ? 36  LEU B CD2 1 
ATOM   4298 N N   . GLY B 1 37  ? 93.642  90.387  114.161 1.00 44.89  ? 37  GLY B N   1 
ATOM   4299 C CA  . GLY B 1 37  ? 94.028  91.768  113.982 1.00 44.89  ? 37  GLY B CA  1 
ATOM   4300 C C   . GLY B 1 37  ? 95.169  92.173  114.905 1.00 44.89  ? 37  GLY B C   1 
ATOM   4301 O O   . GLY B 1 37  ? 95.427  91.555  115.944 1.00 44.89  ? 37  GLY B O   1 
ATOM   4302 N N   . ALA B 1 38  ? 95.849  93.251  114.511 1.00 36.43  ? 38  ALA B N   1 
ATOM   4303 C CA  . ALA B 1 38  ? 97.065  93.666  115.203 1.00 36.43  ? 38  ALA B CA  1 
ATOM   4304 C C   . ALA B 1 38  ? 96.772  94.107  116.631 1.00 36.43  ? 38  ALA B C   1 
ATOM   4305 O O   . ALA B 1 38  ? 97.462  93.692  117.567 1.00 36.43  ? 38  ALA B O   1 
ATOM   4306 C CB  . ALA B 1 38  ? 97.749  94.786  114.422 1.00 36.43  ? 38  ALA B CB  1 
ATOM   4307 N N   . THR B 1 39  ? 95.751  94.947  116.816 1.00 32.35  ? 39  THR B N   1 
ATOM   4308 C CA  . THR B 1 39  ? 95.461  95.483  118.144 1.00 32.35  ? 39  THR B CA  1 
ATOM   4309 C C   . THR B 1 39  ? 95.039  94.385  119.114 1.00 32.35  ? 39  THR B C   1 
ATOM   4310 O O   . THR B 1 39  ? 95.502  94.348  120.262 1.00 32.35  ? 39  THR B O   1 
ATOM   4311 C CB  . THR B 1 39  ? 94.375  96.551  118.044 1.00 32.35  ? 39  THR B CB  1 
ATOM   4312 O OG1 . THR B 1 39  ? 94.733  97.500  117.032 1.00 32.35  ? 39  THR B OG1 1 
ATOM   4313 C CG2 . THR B 1 39  ? 94.224  97.268  119.366 1.00 32.35  ? 39  THR B CG2 1 
ATOM   4314 N N   . VAL B 1 40  ? 94.168  93.479  118.668 1.00 34.04  ? 40  VAL B N   1 
ATOM   4315 C CA  . VAL B 1 40  ? 93.710  92.399  119.535 1.00 34.04  ? 40  VAL B CA  1 
ATOM   4316 C C   . VAL B 1 40  ? 94.847  91.435  119.841 1.00 34.04  ? 40  VAL B C   1 
ATOM   4317 O O   . VAL B 1 40  ? 94.983  90.956  120.976 1.00 34.04  ? 40  VAL B O   1 
ATOM   4318 C CB  . VAL B 1 40  ? 92.506  91.685  118.899 1.00 34.04  ? 40  VAL B CB  1 
ATOM   4319 C CG1 . VAL B 1 40  ? 91.963  90.619  119.834 1.00 34.04  ? 40  VAL B CG1 1 
ATOM   4320 C CG2 . VAL B 1 40  ? 91.426  92.698  118.572 1.00 34.04  ? 40  VAL B CG2 1 
ATOM   4321 N N   . GLY B 1 41  ? 95.686  91.137  118.845 1.00 34.80  ? 41  GLY B N   1 
ATOM   4322 C CA  . GLY B 1 41  ? 96.838  90.288  119.103 1.00 34.80  ? 41  GLY B CA  1 
ATOM   4323 C C   . GLY B 1 41  ? 97.802  90.901  120.101 1.00 34.80  ? 41  GLY B C   1 
ATOM   4324 O O   . GLY B 1 41  ? 98.322  90.212  120.982 1.00 34.80  ? 41  GLY B O   1 
ATOM   4325 N N   . VAL B 1 42  ? 98.040  92.209  119.985 1.00 31.07  ? 42  VAL B N   1 
ATOM   4326 C CA  . VAL B 1 42  ? 98.911  92.903  120.929 1.00 31.07  ? 42  VAL B CA  1 
ATOM   4327 C C   . VAL B 1 42  ? 98.315  92.879  122.329 1.00 31.07  ? 42  VAL B C   1 
ATOM   4328 O O   . VAL B 1 42  ? 99.032  92.660  123.313 1.00 31.07  ? 42  VAL B O   1 
ATOM   4329 C CB  . VAL B 1 42  ? 99.186  94.339  120.444 1.00 31.07  ? 42  VAL B CB  1 
ATOM   4330 C CG1 . VAL B 1 42  ? 99.874  95.136  121.520 1.00 31.07  ? 42  VAL B CG1 1 
ATOM   4331 C CG2 . VAL B 1 42  ? 100.071 94.307  119.218 1.00 31.07  ? 42  VAL B CG2 1 
ATOM   4332 N N   . LEU B 1 43  ? 97.002  93.100  122.446 1.00 32.27  ? 43  LEU B N   1 
ATOM   4333 C CA  . LEU B 1 43  ? 96.363  93.035  123.758 1.00 32.27  ? 43  LEU B CA  1 
ATOM   4334 C C   . LEU B 1 43  ? 96.492  91.650  124.379 1.00 32.27  ? 43  LEU B C   1 
ATOM   4335 O O   . LEU B 1 43  ? 96.794  91.525  125.571 1.00 32.27  ? 43  LEU B O   1 
ATOM   4336 C CB  . LEU B 1 43  ? 94.894  93.430  123.654 1.00 32.27  ? 43  LEU B CB  1 
ATOM   4337 C CG  . LEU B 1 43  ? 94.247  93.848  124.977 1.00 32.27  ? 43  LEU B CG  1 
ATOM   4338 C CD1 . LEU B 1 43  ? 94.760  95.186  125.480 1.00 32.27  ? 43  LEU B CD1 1 
ATOM   4339 C CD2 . LEU B 1 43  ? 92.738  93.872  124.825 1.00 32.27  ? 43  LEU B CD2 1 
ATOM   4340 N N   . ILE B 1 44  ? 96.282  90.600  123.585 1.00 32.86  ? 44  ILE B N   1 
ATOM   4341 C CA  . ILE B 1 44  ? 96.381  89.241  124.112 1.00 32.86  ? 44  ILE B CA  1 
ATOM   4342 C C   . ILE B 1 44  ? 97.807  88.941  124.559 1.00 32.86  ? 44  ILE B C   1 
ATOM   4343 O O   . ILE B 1 44  ? 98.031  88.405  125.654 1.00 32.86  ? 44  ILE B O   1 
ATOM   4344 C CB  . ILE B 1 44  ? 95.884  88.226  123.065 1.00 32.86  ? 44  ILE B CB  1 
ATOM   4345 C CG1 . ILE B 1 44  ? 94.361  88.304  122.936 1.00 32.86  ? 44  ILE B CG1 1 
ATOM   4346 C CG2 . ILE B 1 44  ? 96.318  86.818  123.428 1.00 32.86  ? 44  ILE B CG2 1 
ATOM   4347 C CD1 . ILE B 1 44  ? 93.839  87.799  121.613 1.00 32.86  ? 44  ILE B CD1 1 
ATOM   4348 N N   . VAL B 1 45  ? 98.794  89.297  123.734 1.00 34.09  ? 45  VAL B N   1 
ATOM   4349 C CA  . VAL B 1 45  ? 100.185 89.011  124.077 1.00 34.09  ? 45  VAL B CA  1 
ATOM   4350 C C   . VAL B 1 45  ? 100.612 89.815  125.300 1.00 34.09  ? 45  VAL B C   1 
ATOM   4351 O O   . VAL B 1 45  ? 101.320 89.303  126.176 1.00 34.09  ? 45  VAL B O   1 
ATOM   4352 C CB  . VAL B 1 45  ? 101.096 89.275  122.863 1.00 34.09  ? 45  VAL B CB  1 
ATOM   4353 C CG1 . VAL B 1 45  ? 102.500 89.664  123.299 1.00 34.09  ? 45  VAL B CG1 1 
ATOM   4354 C CG2 . VAL B 1 45  ? 101.148 88.046  121.970 1.00 34.09  ? 45  VAL B CG2 1 
ATOM   4355 N N   . ALA B 1 46  ? 100.175 91.074  125.392 1.00 33.13  ? 46  ALA B N   1 
ATOM   4356 C CA  . ALA B 1 46  ? 100.486 91.889  126.562 1.00 33.13  ? 46  ALA B CA  1 
ATOM   4357 C C   . ALA B 1 46  ? 99.865  91.305  127.822 1.00 33.13  ? 46  ALA B C   1 
ATOM   4358 O O   . ALA B 1 46  ? 100.499 91.288  128.882 1.00 33.13  ? 46  ALA B O   1 
ATOM   4359 C CB  . ALA B 1 46  ? 100.003 93.321  126.344 1.00 33.13  ? 46  ALA B CB  1 
ATOM   4360 N N   . LEU B 1 47  ? 98.621  90.826  127.727 1.00 34.47  ? 47  LEU B N   1 
ATOM   4361 C CA  . LEU B 1 47  ? 97.975  90.224  128.888 1.00 34.47  ? 47  LEU B CA  1 
ATOM   4362 C C   . LEU B 1 47  ? 98.710  88.971  129.340 1.00 34.47  ? 47  LEU B C   1 
ATOM   4363 O O   . LEU B 1 47  ? 98.874  88.740  130.543 1.00 34.47  ? 47  LEU B O   1 
ATOM   4364 C CB  . LEU B 1 47  ? 96.514  89.907  128.573 1.00 34.47  ? 47  LEU B CB  1 
ATOM   4365 C CG  . LEU B 1 47  ? 95.553  91.095  128.622 1.00 34.47  ? 47  LEU B CG  1 
ATOM   4366 C CD1 . LEU B 1 47  ? 94.113  90.634  128.464 1.00 34.47  ? 47  LEU B CD1 1 
ATOM   4367 C CD2 . LEU B 1 47  ? 95.733  91.891  129.905 1.00 34.47  ? 47  LEU B CD2 1 
ATOM   4368 N N   . LEU B 1 48  ? 99.155  88.143  128.391 1.00 34.94  ? 48  LEU B N   1 
ATOM   4369 C CA  . LEU B 1 48  ? 99.910  86.949  128.768 1.00 34.94  ? 48  LEU B CA  1 
ATOM   4370 C C   . LEU B 1 48  ? 101.267 87.305  129.368 1.00 34.94  ? 48  LEU B C   1 
ATOM   4371 O O   . LEU B 1 48  ? 101.710 86.669  130.332 1.00 34.94  ? 48  LEU B O   1 
ATOM   4372 C CB  . LEU B 1 48  ? 100.079 86.017  127.568 1.00 34.94  ? 48  LEU B CB  1 
ATOM   4373 C CG  . LEU B 1 48  ? 98.791  85.597  126.859 1.00 34.94  ? 48  LEU B CG  1 
ATOM   4374 C CD1 . LEU B 1 48  ? 99.089  84.659  125.701 1.00 34.94  ? 48  LEU B CD1 1 
ATOM   4375 C CD2 . LEU B 1 48  ? 97.826  84.957  127.844 1.00 34.94  ? 48  LEU B CD2 1 
ATOM   4376 N N   . ILE B 1 49  ? 101.943 88.315  128.815 1.00 35.53  ? 49  ILE B N   1 
ATOM   4377 C CA  . ILE B 1 49  ? 103.278 88.669  129.293 1.00 35.53  ? 49  ILE B CA  1 
ATOM   4378 C C   . ILE B 1 49  ? 103.211 89.295  130.682 1.00 35.53  ? 49  ILE B C   1 
ATOM   4379 O O   . ILE B 1 49  ? 104.046 89.004  131.548 1.00 35.53  ? 49  ILE B O   1 
ATOM   4380 C CB  . ILE B 1 49  ? 103.976 89.594  128.277 1.00 35.53  ? 49  ILE B CB  1 
ATOM   4381 C CG1 . ILE B 1 49  ? 104.497 88.782  127.090 1.00 35.53  ? 49  ILE B CG1 1 
ATOM   4382 C CG2 . ILE B 1 49  ? 105.117 90.366  128.924 1.00 35.53  ? 49  ILE B CG2 1 
ATOM   4383 C CD1 . ILE B 1 49  ? 105.301 89.593  126.097 1.00 35.53  ? 49  ILE B CD1 1 
ATOM   4384 N N   . GLY B 1 50  ? 102.201 90.132  130.932 1.00 39.85  ? 50  GLY B N   1 
ATOM   4385 C CA  . GLY B 1 50  ? 102.147 90.899  132.166 1.00 39.85  ? 50  GLY B CA  1 
ATOM   4386 C C   . GLY B 1 50  ? 101.967 90.077  133.425 1.00 39.85  ? 50  GLY B C   1 
ATOM   4387 O O   . GLY B 1 50  ? 102.145 90.609  134.526 1.00 39.85  ? 50  GLY B O   1 
ATOM   4388 N N   . GLN B 1 51  ? 101.602 88.799  133.295 1.00 41.59  ? 51  GLN B N   1 
ATOM   4389 C CA  . GLN B 1 51  ? 101.472 87.946  134.472 1.00 41.59  ? 51  GLN B CA  1 
ATOM   4390 C C   . GLN B 1 51  ? 102.812 87.716  135.157 1.00 41.59  ? 51  GLN B C   1 
ATOM   4391 O O   . GLN B 1 51  ? 102.862 87.564  136.383 1.00 41.59  ? 51  GLN B O   1 
ATOM   4392 C CB  . GLN B 1 51  ? 100.843 86.607  134.086 1.00 41.59  ? 51  GLN B CB  1 
ATOM   4393 C CG  . GLN B 1 51  ? 99.614  86.727  133.208 1.00 41.59  ? 51  GLN B CG  1 
ATOM   4394 C CD  . GLN B 1 51  ? 98.330  86.702  134.010 1.00 41.59  ? 51  GLN B CD  1 
ATOM   4395 O OE1 . GLN B 1 51  ? 98.244  87.295  135.085 1.00 41.59  ? 51  GLN B OE1 1 
ATOM   4396 N NE2 . GLN B 1 51  ? 97.321  86.012  133.491 1.00 41.59  ? 51  GLN B NE2 1 
ATOM   4397 N N   . LEU B 1 52  ? 103.903 87.674  134.388 1.00 43.66  ? 52  LEU B N   1 
ATOM   4398 C CA  . LEU B 1 52  ? 105.208 87.366  134.962 1.00 43.66  ? 52  LEU B CA  1 
ATOM   4399 C C   . LEU B 1 52  ? 105.689 88.466  135.901 1.00 43.66  ? 52  LEU B C   1 
ATOM   4400 O O   . LEU B 1 52  ? 106.257 88.178  136.961 1.00 43.66  ? 52  LEU B O   1 
ATOM   4401 C CB  . LEU B 1 52  ? 106.229 87.131  133.847 1.00 43.66  ? 52  LEU B CB  1 
ATOM   4402 C CG  . LEU B 1 52  ? 105.857 86.119  132.762 1.00 43.66  ? 52  LEU B CG  1 
ATOM   4403 C CD1 . LEU B 1 52  ? 107.036 85.871  131.837 1.00 43.66  ? 52  LEU B CD1 1 
ATOM   4404 C CD2 . LEU B 1 52  ? 105.381 84.816  133.378 1.00 43.66  ? 52  LEU B CD2 1 
ATOM   4405 N N   . GLY B 1 53  ? 105.471 89.727  135.537 1.00 49.25  ? 53  GLY B N   1 
ATOM   4406 C CA  . GLY B 1 53  ? 106.031 90.823  136.304 1.00 49.25  ? 53  GLY B CA  1 
ATOM   4407 C C   . GLY B 1 53  ? 105.027 91.742  136.971 1.00 49.25  ? 53  GLY B C   1 
ATOM   4408 O O   . GLY B 1 53  ? 103.830 91.447  137.022 1.00 49.25  ? 53  GLY B O   1 
ATOM   4409 N N   . VAL B 1 54  ? 105.521 92.859  137.501 1.00 51.49  ? 54  VAL B N   1 
ATOM   4410 C CA  . VAL B 1 54  ? 104.704 93.829  138.222 1.00 51.49  ? 54  VAL B CA  1 
ATOM   4411 C C   . VAL B 1 54  ? 104.872 95.196  137.555 1.00 51.49  ? 54  VAL B C   1 
ATOM   4412 O O   . VAL B 1 54  ? 104.822 96.242  138.213 1.00 51.49  ? 54  VAL B O   1 
ATOM   4413 C CB  . VAL B 1 54  ? 105.072 93.822  139.725 1.00 51.49  ? 54  VAL B CB  1 
ATOM   4414 C CG1 . VAL B 1 54  ? 106.483 94.370  139.976 1.00 51.49  ? 54  VAL B CG1 1 
ATOM   4415 C CG2 . VAL B 1 54  ? 104.002 94.509  140.588 1.00 51.49  ? 54  VAL B CG2 1 
ATOM   4416 N N   . PHE B 1 55  ? 105.051 95.189  136.232 1.00 46.57  ? 55  PHE B N   1 
ATOM   4417 C CA  . PHE B 1 55  ? 105.417 96.398  135.498 1.00 46.57  ? 55  PHE B CA  1 
ATOM   4418 C C   . PHE B 1 55  ? 104.376 97.499  135.691 1.00 46.57  ? 55  PHE B C   1 
ATOM   4419 O O   . PHE B 1 55  ? 103.171 97.233  135.589 1.00 46.57  ? 55  PHE B O   1 
ATOM   4420 C CB  . PHE B 1 55  ? 105.552 96.104  134.005 1.00 46.57  ? 55  PHE B CB  1 
ATOM   4421 C CG  . PHE B 1 55  ? 105.899 94.680  133.689 1.00 46.57  ? 55  PHE B CG  1 
ATOM   4422 C CD1 . PHE B 1 55  ? 107.178 94.198  133.897 1.00 46.57  ? 55  PHE B CD1 1 
ATOM   4423 C CD2 . PHE B 1 55  ? 104.942 93.827  133.169 1.00 46.57  ? 55  PHE B CD2 1 
ATOM   4424 C CE1 . PHE B 1 55  ? 107.492 92.887  133.598 1.00 46.57  ? 55  PHE B CE1 1 
ATOM   4425 C CE2 . PHE B 1 55  ? 105.251 92.518  132.870 1.00 46.57  ? 55  PHE B CE2 1 
ATOM   4426 C CZ  . PHE B 1 55  ? 106.527 92.047  133.082 1.00 46.57  ? 55  PHE B CZ  1 
ATOM   4427 N N   . PRO B 1 56  ? 104.790 98.730  135.967 1.00 45.60  ? 56  PRO B N   1 
ATOM   4428 C CA  . PRO B 1 56  ? 103.847 99.848  136.053 1.00 45.60  ? 56  PRO B CA  1 
ATOM   4429 C C   . PRO B 1 56  ? 103.562 100.418 134.666 1.00 45.60  ? 56  PRO B C   1 
ATOM   4430 O O   . PRO B 1 56  ? 104.006 99.894  133.647 1.00 45.60  ? 56  PRO B O   1 
ATOM   4431 C CB  . PRO B 1 56  ? 104.589 100.851 136.935 1.00 45.60  ? 56  PRO B CB  1 
ATOM   4432 C CG  . PRO B 1 56  ? 106.023 100.624 136.595 1.00 45.60  ? 56  PRO B CG  1 
ATOM   4433 C CD  . PRO B 1 56  ? 106.169 99.153  136.264 1.00 45.60  ? 56  PRO B CD  1 
ATOM   4434 N N   . ARG B 1 57  ? 102.808 101.514 134.645 1.00 39.20  ? 57  ARG B N   1 
ATOM   4435 C CA  . ARG B 1 57  ? 102.367 102.144 133.407 1.00 39.20  ? 57  ARG B CA  1 
ATOM   4436 C C   . ARG B 1 57  ? 102.891 103.571 133.344 1.00 39.20  ? 57  ARG B C   1 
ATOM   4437 O O   . ARG B 1 57  ? 102.779 104.320 134.318 1.00 39.20  ? 57  ARG B O   1 
ATOM   4438 C CB  . ARG B 1 57  ? 100.839 102.125 133.310 1.00 39.20  ? 57  ARG B CB  1 
ATOM   4439 C CG  . ARG B 1 57  ? 100.220 103.226 132.470 1.00 39.20  ? 57  ARG B CG  1 
ATOM   4440 C CD  . ARG B 1 57  ? 98.699  103.128 132.517 1.00 39.20  ? 57  ARG B CD  1 
ATOM   4441 N NE  . ARG B 1 57  ? 98.032  104.359 132.111 1.00 39.20  ? 57  ARG B NE  1 
ATOM   4442 C CZ  . ARG B 1 57  ? 97.964  104.803 130.863 1.00 39.20  ? 57  ARG B CZ  1 
ATOM   4443 N NH1 . ARG B 1 57  ? 98.498  104.129 129.858 1.00 39.20  ? 57  ARG B NH1 1 
ATOM   4444 N NH2 . ARG B 1 57  ? 97.336  105.949 130.616 1.00 39.20  ? 57  ARG B NH2 1 
ATOM   4445 N N   . ASP B 1 58  ? 103.464 103.939 132.200 1.00 41.61  ? 58  ASP B N   1 
ATOM   4446 C CA  . ASP B 1 58  ? 104.005 105.275 131.980 1.00 41.61  ? 58  ASP B CA  1 
ATOM   4447 C C   . ASP B 1 58  ? 102.996 106.099 131.191 1.00 41.61  ? 58  ASP B C   1 
ATOM   4448 O O   . ASP B 1 58  ? 102.587 105.704 130.094 1.00 41.61  ? 58  ASP B O   1 
ATOM   4449 C CB  . ASP B 1 58  ? 105.339 105.210 131.240 1.00 41.61  ? 58  ASP B CB  1 
ATOM   4450 C CG  . ASP B 1 58  ? 106.038 106.551 131.190 1.00 41.61  ? 58  ASP B CG  1 
ATOM   4451 O OD1 . ASP B 1 58  ? 106.437 107.057 132.260 1.00 41.61  ? 58  ASP B OD1 1 
ATOM   4452 O OD2 . ASP B 1 58  ? 106.182 107.105 130.080 1.00 41.61  ? 58  ASP B OD2 1 
ATOM   4453 N N   . THR B 1 59  ? 102.598 107.243 131.751 1.00 40.95  ? 59  THR B N   1 
ATOM   4454 C CA  . THR B 1 59  ? 101.545 108.050 131.146 1.00 40.95  ? 59  THR B CA  1 
ATOM   4455 C C   . THR B 1 59  ? 102.042 108.838 129.937 1.00 40.95  ? 59  THR B C   1 
ATOM   4456 O O   . THR B 1 59  ? 101.328 108.955 128.934 1.00 40.95  ? 59  THR B O   1 
ATOM   4457 C CB  . THR B 1 59  ? 100.958 108.997 132.193 1.00 40.95  ? 59  THR B CB  1 
ATOM   4458 O OG1 . THR B 1 59  ? 100.740 108.279 133.413 1.00 40.95  ? 59  THR B OG1 1 
ATOM   4459 C CG2 . THR B 1 59  ? 99.634  109.558 131.717 1.00 40.95  ? 59  THR B CG2 1 
ATOM   4460 N N   . LEU B 1 60  ? 103.261 109.385 130.018 1.00 38.48  ? 60  LEU B N   1 
ATOM   4461 C CA  . LEU B 1 60  ? 103.748 110.293 128.981 1.00 38.48  ? 60  LEU B CA  1 
ATOM   4462 C C   . LEU B 1 60  ? 103.954 109.581 127.652 1.00 38.48  ? 60  LEU B C   1 
ATOM   4463 O O   . LEU B 1 60  ? 103.607 110.122 126.594 1.00 38.48  ? 60  LEU B O   1 
ATOM   4464 C CB  . LEU B 1 60  ? 105.053 110.948 129.429 1.00 38.48  ? 60  LEU B CB  1 
ATOM   4465 C CG  . LEU B 1 60  ? 104.926 112.023 130.501 1.00 38.48  ? 60  LEU B CG  1 
ATOM   4466 C CD1 . LEU B 1 60  ? 106.293 112.594 130.834 1.00 38.48  ? 60  LEU B CD1 1 
ATOM   4467 C CD2 . LEU B 1 60  ? 103.980 113.110 130.028 1.00 38.48  ? 60  LEU B CD2 1 
ATOM   4468 N N   . LEU B 1 61  ? 104.536 108.382 127.684 1.00 35.61  ? 61  LEU B N   1 
ATOM   4469 C CA  . LEU B 1 61  ? 104.798 107.647 126.452 1.00 35.61  ? 61  LEU B CA  1 
ATOM   4470 C C   . LEU B 1 61  ? 103.496 107.326 125.728 1.00 35.61  ? 61  LEU B C   1 
ATOM   4471 O O   . LEU B 1 61  ? 103.377 107.520 124.510 1.00 35.61  ? 61  LEU B O   1 
ATOM   4472 C CB  . LEU B 1 61  ? 105.570 106.369 126.775 1.00 35.61  ? 61  LEU B CB  1 
ATOM   4473 C CG  . LEU B 1 61  ? 106.098 105.549 125.603 1.00 35.61  ? 61  LEU B CG  1 
ATOM   4474 C CD1 . LEU B 1 61  ? 107.080 106.374 124.794 1.00 35.61  ? 61  LEU B CD1 1 
ATOM   4475 C CD2 . LEU B 1 61  ? 106.743 104.273 126.104 1.00 35.61  ? 61  LEU B CD2 1 
ATOM   4476 N N   . GLY B 1 62  ? 102.497 106.857 126.479 1.00 33.79  ? 62  GLY B N   1 
ATOM   4477 C CA  . GLY B 1 62  ? 101.203 106.575 125.884 1.00 33.79  ? 62  GLY B CA  1 
ATOM   4478 C C   . GLY B 1 62  ? 100.526 107.818 125.346 1.00 33.79  ? 62  GLY B C   1 
ATOM   4479 O O   . GLY B 1 62  ? 99.947  107.794 124.257 1.00 33.79  ? 62  GLY B O   1 
ATOM   4480 N N   . ASP B 1 63  ? 100.607 108.929 126.087 1.00 34.40  ? 63  ASP B N   1 
ATOM   4481 C CA  . ASP B 1 63  ? 99.990  110.167 125.616 1.00 34.40  ? 63  ASP B CA  1 
ATOM   4482 C C   . ASP B 1 63  ? 100.623 110.648 124.316 1.00 34.40  ? 63  ASP B C   1 
ATOM   4483 O O   . ASP B 1 63  ? 99.913  111.043 123.385 1.00 34.40  ? 63  ASP B O   1 
ATOM   4484 C CB  . ASP B 1 63  ? 100.082 111.252 126.687 1.00 34.40  ? 63  ASP B CB  1 
ATOM   4485 C CG  . ASP B 1 63  ? 98.953  111.172 127.694 1.00 34.40  ? 63  ASP B CG  1 
ATOM   4486 O OD1 . ASP B 1 63  ? 97.778  111.260 127.280 1.00 34.40  ? 63  ASP B OD1 1 
ATOM   4487 O OD2 . ASP B 1 63  ? 99.238  111.032 128.899 1.00 34.40  ? 63  ASP B OD2 1 
ATOM   4488 N N   . ILE B 1 64  ? 101.953 110.610 124.226 1.00 31.37  ? 64  ILE B N   1 
ATOM   4489 C CA  . ILE B 1 64  ? 102.623 111.084 123.015 1.00 31.37  ? 64  ILE B CA  1 
ATOM   4490 C C   . ILE B 1 64  ? 102.312 110.169 121.835 1.00 31.37  ? 64  ILE B C   1 
ATOM   4491 O O   . ILE B 1 64  ? 101.986 110.636 120.734 1.00 31.37  ? 64  ILE B O   1 
ATOM   4492 C CB  . ILE B 1 64  ? 104.138 111.215 123.249 1.00 31.37  ? 64  ILE B CB  1 
ATOM   4493 C CG1 . ILE B 1 64  ? 104.418 112.259 124.329 1.00 31.37  ? 64  ILE B CG1 1 
ATOM   4494 C CG2 . ILE B 1 64  ? 104.846 111.585 121.962 1.00 31.37  ? 64  ILE B CG2 1 
ATOM   4495 C CD1 . ILE B 1 64  ? 105.884 112.482 124.592 1.00 31.37  ? 64  ILE B CD1 1 
ATOM   4496 N N   . PHE B 1 65  ? 102.397 108.851 122.043 1.00 27.23  ? 65  PHE B N   1 
ATOM   4497 C CA  . PHE B 1 65  ? 102.169 107.939 120.931 1.00 27.23  ? 65  PHE B CA  1 
ATOM   4498 C C   . PHE B 1 65  ? 100.698 107.833 120.551 1.00 27.23  ? 65  PHE B C   1 
ATOM   4499 O O   . PHE B 1 65  ? 100.391 107.335 119.463 1.00 27.23  ? 65  PHE B O   1 
ATOM   4500 C CB  . PHE B 1 65  ? 102.745 106.562 121.254 1.00 27.23  ? 65  PHE B CB  1 
ATOM   4501 C CG  . PHE B 1 65  ? 104.164 106.390 120.797 1.00 27.23  ? 65  PHE B CG  1 
ATOM   4502 C CD1 . PHE B 1 65  ? 104.461 106.288 119.449 1.00 27.23  ? 65  PHE B CD1 1 
ATOM   4503 C CD2 . PHE B 1 65  ? 105.203 106.352 121.709 1.00 27.23  ? 65  PHE B CD2 1 
ATOM   4504 C CE1 . PHE B 1 65  ? 105.764 106.137 119.021 1.00 27.23  ? 65  PHE B CE1 1 
ATOM   4505 C CE2 . PHE B 1 65  ? 106.509 106.203 121.286 1.00 27.23  ? 65  PHE B CE2 1 
ATOM   4506 C CZ  . PHE B 1 65  ? 106.789 106.095 119.941 1.00 27.23  ? 65  PHE B CZ  1 
ATOM   4507 N N   . PHE B 1 66  ? 99.784  108.288 121.406 1.00 29.47  ? 66  PHE B N   1 
ATOM   4508 C CA  . PHE B 1 66  ? 98.388  108.394 121.004 1.00 29.47  ? 66  PHE B CA  1 
ATOM   4509 C C   . PHE B 1 66  ? 98.089  109.718 120.318 1.00 29.47  ? 66  PHE B C   1 
ATOM   4510 O O   . PHE B 1 66  ? 97.254  109.764 119.404 1.00 29.47  ? 66  PHE B O   1 
ATOM   4511 C CB  . PHE B 1 66  ? 97.472  108.222 122.219 1.00 29.47  ? 66  PHE B CB  1 
ATOM   4512 C CG  . PHE B 1 66  ? 96.037  107.985 121.863 1.00 29.47  ? 66  PHE B CG  1 
ATOM   4513 C CD1 . PHE B 1 66  ? 95.644  106.787 121.293 1.00 29.47  ? 66  PHE B CD1 1 
ATOM   4514 C CD2 . PHE B 1 66  ? 95.082  108.959 122.091 1.00 29.47  ? 66  PHE B CD2 1 
ATOM   4515 C CE1 . PHE B 1 66  ? 94.325  106.563 120.961 1.00 29.47  ? 66  PHE B CE1 1 
ATOM   4516 C CE2 . PHE B 1 66  ? 93.760  108.741 121.761 1.00 29.47  ? 66  PHE B CE2 1 
ATOM   4517 C CZ  . PHE B 1 66  ? 93.381  107.542 121.195 1.00 29.47  ? 66  PHE B CZ  1 
ATOM   4518 N N   . ASP B 1 67  ? 98.756  110.796 120.739 1.00 31.51  ? 67  ASP B N   1 
ATOM   4519 C CA  . ASP B 1 67  ? 98.607  112.074 120.054 1.00 31.51  ? 67  ASP B CA  1 
ATOM   4520 C C   . ASP B 1 67  ? 99.118  111.989 118.623 1.00 31.51  ? 67  ASP B C   1 
ATOM   4521 O O   . ASP B 1 67  ? 98.521  112.568 117.708 1.00 31.51  ? 67  ASP B O   1 
ATOM   4522 C CB  . ASP B 1 67  ? 99.340  113.169 120.825 1.00 31.51  ? 67  ASP B CB  1 
ATOM   4523 C CG  . ASP B 1 67  ? 98.397  114.063 121.602 1.00 31.51  ? 67  ASP B CG  1 
ATOM   4524 O OD1 . ASP B 1 67  ? 97.357  114.462 121.039 1.00 31.51  ? 67  ASP B OD1 1 
ATOM   4525 O OD2 . ASP B 1 67  ? 98.690  114.362 122.779 1.00 31.51  ? 67  ASP B OD2 1 
ATOM   4526 N N   . PHE B 1 68  ? 100.224 111.267 118.409 1.00 29.52  ? 68  PHE B N   1 
ATOM   4527 C CA  . PHE B 1 68  ? 100.709 111.059 117.045 1.00 29.52  ? 68  PHE B CA  1 
ATOM   4528 C C   . PHE B 1 68  ? 99.681  110.316 116.196 1.00 29.52  ? 68  PHE B C   1 
ATOM   4529 O O   . PHE B 1 68  ? 99.444  110.678 115.036 1.00 29.52  ? 68  PHE B O   1 
ATOM   4530 C CB  . PHE B 1 68  ? 102.034 110.299 117.063 1.00 29.52  ? 68  PHE B CB  1 
ATOM   4531 C CG  . PHE B 1 68  ? 103.227 111.161 117.355 1.00 29.52  ? 68  PHE B CG  1 
ATOM   4532 C CD1 . PHE B 1 68  ? 103.109 112.539 117.409 1.00 29.52  ? 68  PHE B CD1 1 
ATOM   4533 C CD2 . PHE B 1 68  ? 104.469 110.592 117.574 1.00 29.52  ? 68  PHE B CD2 1 
ATOM   4534 C CE1 . PHE B 1 68  ? 104.208 113.331 117.676 1.00 29.52  ? 68  PHE B CE1 1 
ATOM   4535 C CE2 . PHE B 1 68  ? 105.569 111.377 117.842 1.00 29.52  ? 68  PHE B CE2 1 
ATOM   4536 C CZ  . PHE B 1 68  ? 105.438 112.748 117.894 1.00 29.52  ? 68  PHE B CZ  1 
ATOM   4537 N N   . PHE B 1 69  ? 99.060  109.279 116.763 1.00 30.82  ? 69  PHE B N   1 
ATOM   4538 C CA  . PHE B 1 69  ? 98.033  108.523 116.049 1.00 30.82  ? 69  PHE B CA  1 
ATOM   4539 C C   . PHE B 1 69  ? 96.849  109.407 115.681 1.00 30.82  ? 69  PHE B C   1 
ATOM   4540 O O   . PHE B 1 69  ? 96.358  109.372 114.545 1.00 30.82  ? 69  PHE B O   1 
ATOM   4541 C CB  . PHE B 1 69  ? 97.581  107.345 116.913 1.00 30.82  ? 69  PHE B CB  1 
ATOM   4542 C CG  . PHE B 1 69  ? 96.220  106.812 116.562 1.00 30.82  ? 69  PHE B CG  1 
ATOM   4543 C CD1 . PHE B 1 69  ? 96.003  106.139 115.375 1.00 30.82  ? 69  PHE B CD1 1 
ATOM   4544 C CD2 . PHE B 1 69  ? 95.156  106.985 117.429 1.00 30.82  ? 69  PHE B CD2 1 
ATOM   4545 C CE1 . PHE B 1 69  ? 94.752  105.647 115.058 1.00 30.82  ? 69  PHE B CE1 1 
ATOM   4546 C CE2 . PHE B 1 69  ? 93.904  106.498 117.116 1.00 30.82  ? 69  PHE B CE2 1 
ATOM   4547 C CZ  . PHE B 1 69  ? 93.702  105.829 115.930 1.00 30.82  ? 69  PHE B CZ  1 
ATOM   4548 N N   . MET B 1 70  ? 96.377  110.209 116.637 1.00 32.02  ? 70  MET B N   1 
ATOM   4549 C CA  . MET B 1 70  ? 95.230  111.073 116.377 1.00 32.02  ? 70  MET B CA  1 
ATOM   4550 C C   . MET B 1 70  ? 95.561  112.128 115.327 1.00 32.02  ? 70  MET B C   1 
ATOM   4551 O O   . MET B 1 70  ? 94.735  112.426 114.456 1.00 32.02  ? 70  MET B O   1 
ATOM   4552 C CB  . MET B 1 70  ? 94.760  111.727 117.673 1.00 32.02  ? 70  MET B CB  1 
ATOM   4553 C CG  . MET B 1 70  ? 93.739  110.899 118.434 1.00 32.02  ? 70  MET B CG  1 
ATOM   4554 S SD  . MET B 1 70  ? 92.313  110.462 117.425 1.00 32.02  ? 70  MET B SD  1 
ATOM   4555 C CE  . MET B 1 70  ? 91.242  109.726 118.655 1.00 32.02  ? 70  MET B CE  1 
ATOM   4556 N N   . PHE B 1 71  ? 96.768  112.696 115.389 1.00 26.81  ? 71  PHE B N   1 
ATOM   4557 C CA  . PHE B 1 71  ? 97.174  113.685 114.396 1.00 26.81  ? 71  PHE B CA  1 
ATOM   4558 C C   . PHE B 1 71  ? 97.263  113.065 113.008 1.00 26.81  ? 71  PHE B C   1 
ATOM   4559 O O   . PHE B 1 71  ? 96.848  113.681 112.020 1.00 26.81  ? 71  PHE B O   1 
ATOM   4560 C CB  . PHE B 1 71  ? 98.507  114.315 114.808 1.00 26.81  ? 71  PHE B CB  1 
ATOM   4561 C CG  . PHE B 1 71  ? 98.976  115.418 113.899 1.00 26.81  ? 71  PHE B CG  1 
ATOM   4562 C CD1 . PHE B 1 71  ? 99.738  115.144 112.775 1.00 26.81  ? 71  PHE B CD1 1 
ATOM   4563 C CD2 . PHE B 1 71  ? 98.654  116.735 114.175 1.00 26.81  ? 71  PHE B CD2 1 
ATOM   4564 C CE1 . PHE B 1 71  ? 100.165 116.162 111.946 1.00 26.81  ? 71  PHE B CE1 1 
ATOM   4565 C CE2 . PHE B 1 71  ? 99.079  117.755 113.349 1.00 26.81  ? 71  PHE B CE2 1 
ATOM   4566 C CZ  . PHE B 1 71  ? 99.835  117.467 112.235 1.00 26.81  ? 71  PHE B CZ  1 
ATOM   4567 N N   . ALA B 1 72  ? 97.802  111.846 112.912 1.00 33.50  ? 72  ALA B N   1 
ATOM   4568 C CA  . ALA B 1 72  ? 97.883  111.176 111.617 1.00 33.50  ? 72  ALA B CA  1 
ATOM   4569 C C   . ALA B 1 72  ? 96.497  110.892 111.050 1.00 33.50  ? 72  ALA B C   1 
ATOM   4570 O O   . ALA B 1 72  ? 96.255  111.088 109.851 1.00 33.50  ? 72  ALA B O   1 
ATOM   4571 C CB  . ALA B 1 72  ? 98.685  109.883 111.745 1.00 33.50  ? 72  ALA B CB  1 
ATOM   4572 N N   . ILE B 1 73  ? 95.574  110.429 111.898 1.00 32.40  ? 73  ILE B N   1 
ATOM   4573 C CA  . ILE B 1 73  ? 94.216  110.153 111.435 1.00 32.40  ? 73  ILE B CA  1 
ATOM   4574 C C   . ILE B 1 73  ? 93.541  111.436 110.964 1.00 32.40  ? 73  ILE B C   1 
ATOM   4575 O O   . ILE B 1 73  ? 92.884  111.459 109.913 1.00 32.40  ? 73  ILE B O   1 
ATOM   4576 C CB  . ILE B 1 73  ? 93.406  109.449 112.540 1.00 32.40  ? 73  ILE B CB  1 
ATOM   4577 C CG1 . ILE B 1 73  ? 93.703  107.950 112.535 1.00 32.40  ? 73  ILE B CG1 1 
ATOM   4578 C CG2 . ILE B 1 73  ? 91.917  109.680 112.358 1.00 32.40  ? 73  ILE B CG2 1 
ATOM   4579 C CD1 . ILE B 1 73  ? 93.178  107.232 111.314 1.00 32.40  ? 73  ILE B CD1 1 
ATOM   4580 N N   . GLY B 1 74  ? 93.701  112.525 111.722 1.00 35.09  ? 74  GLY B N   1 
ATOM   4581 C CA  . GLY B 1 74  ? 93.120  113.792 111.308 1.00 35.09  ? 74  GLY B CA  1 
ATOM   4582 C C   . GLY B 1 74  ? 93.700  114.306 110.004 1.00 35.09  ? 74  GLY B C   1 
ATOM   4583 O O   . GLY B 1 74  ? 92.974  114.826 109.153 1.00 35.09  ? 74  GLY B O   1 
ATOM   4584 N N   . TYR B 1 75  ? 95.016  114.161 109.826 1.00 41.43  ? 75  TYR B N   1 
ATOM   4585 C CA  . TYR B 1 75  ? 95.649  114.588 108.584 1.00 41.43  ? 75  TYR B CA  1 
ATOM   4586 C C   . TYR B 1 75  ? 95.144  113.783 107.396 1.00 41.43  ? 75  TYR B C   1 
ATOM   4587 O O   . TYR B 1 75  ? 94.894  114.341 106.322 1.00 41.43  ? 75  TYR B O   1 
ATOM   4588 C CB  . TYR B 1 75  ? 97.167  114.468 108.700 1.00 41.43  ? 75  TYR B CB  1 
ATOM   4589 C CG  . TYR B 1 75  ? 97.929  115.491 107.891 1.00 41.43  ? 75  TYR B CG  1 
ATOM   4590 C CD1 . TYR B 1 75  ? 97.983  116.819 108.288 1.00 41.43  ? 75  TYR B CD1 1 
ATOM   4591 C CD2 . TYR B 1 75  ? 98.591  115.127 106.729 1.00 41.43  ? 75  TYR B CD2 1 
ATOM   4592 C CE1 . TYR B 1 75  ? 98.681  117.756 107.551 1.00 41.43  ? 75  TYR B CE1 1 
ATOM   4593 C CE2 . TYR B 1 75  ? 99.289  116.055 105.984 1.00 41.43  ? 75  TYR B CE2 1 
ATOM   4594 C CZ  . TYR B 1 75  ? 99.332  117.366 106.399 1.00 41.43  ? 75  TYR B CZ  1 
ATOM   4595 O OH  . TYR B 1 75  ? 100.027 118.290 105.658 1.00 41.43  ? 75  TYR B OH  1 
ATOM   4596 N N   . ARG B 1 76  ? 94.996  112.465 107.563 1.00 42.38  ? 76  ARG B N   1 
ATOM   4597 C CA  . ARG B 1 76  ? 94.501  111.650 106.456 1.00 42.38  ? 76  ARG B CA  1 
ATOM   4598 C C   . ARG B 1 76  ? 93.049  111.976 106.130 1.00 42.38  ? 76  ARG B C   1 
ATOM   4599 O O   . ARG B 1 76  ? 92.669  112.038 104.955 1.00 42.38  ? 76  ARG B O   1 
ATOM   4600 C CB  . ARG B 1 76  ? 94.657  110.164 106.773 1.00 42.38  ? 76  ARG B CB  1 
ATOM   4601 C CG  . ARG B 1 76  ? 94.266  109.262 105.612 1.00 42.38  ? 76  ARG B CG  1 
ATOM   4602 C CD  . ARG B 1 76  ? 94.770  107.842 105.794 1.00 42.38  ? 76  ARG B CD  1 
ATOM   4603 N NE  . ARG B 1 76  ? 93.982  107.100 106.769 1.00 42.38  ? 76  ARG B NE  1 
ATOM   4604 C CZ  . ARG B 1 76  ? 93.285  106.008 106.489 1.00 42.38  ? 76  ARG B CZ  1 
ATOM   4605 N NH1 . ARG B 1 76  ? 93.254  105.503 105.266 1.00 42.38  ? 76  ARG B NH1 1 
ATOM   4606 N NH2 . ARG B 1 76  ? 92.598  105.410 107.458 1.00 42.38  ? 76  ARG B NH2 1 
ATOM   4607 N N   . VAL B 1 77  ? 92.220  112.192 107.156 1.00 43.02  ? 77  VAL B N   1 
ATOM   4608 C CA  . VAL B 1 77  ? 90.806  112.474 106.933 1.00 43.02  ? 77  VAL B CA  1 
ATOM   4609 C C   . VAL B 1 77  ? 90.590  113.875 106.365 1.00 43.02  ? 77  VAL B C   1 
ATOM   4610 O O   . VAL B 1 77  ? 89.618  114.098 105.634 1.00 43.02  ? 77  VAL B O   1 
ATOM   4611 C CB  . VAL B 1 77  ? 90.044  112.239 108.257 1.00 43.02  ? 77  VAL B CB  1 
ATOM   4612 C CG1 . VAL B 1 77  ? 88.699  112.951 108.287 1.00 43.02  ? 77  VAL B CG1 1 
ATOM   4613 C CG2 . VAL B 1 77  ? 89.855  110.747 108.491 1.00 43.02  ? 77  VAL B CG2 1 
ATOM   4614 N N   . GLY B 1 78  ? 91.517  114.801 106.628 1.00 45.64  ? 78  GLY B N   1 
ATOM   4615 C CA  . GLY B 1 78  ? 91.378  116.211 106.318 1.00 45.64  ? 78  GLY B CA  1 
ATOM   4616 C C   . GLY B 1 78  ? 90.777  116.606 104.979 1.00 45.64  ? 78  GLY B C   1 
ATOM   4617 O O   . GLY B 1 78  ? 89.723  117.247 104.926 1.00 45.64  ? 78  GLY B O   1 
ATOM   4618 N N   . PRO B 1 79  ? 91.444  116.258 103.872 1.00 47.69  ? 79  PRO B N   1 
ATOM   4619 C CA  . PRO B 1 79  ? 90.952  116.704 102.555 1.00 47.69  ? 79  PRO B CA  1 
ATOM   4620 C C   . PRO B 1 79  ? 89.556  116.214 102.206 1.00 47.69  ? 79  PRO B C   1 
ATOM   4621 O O   . PRO B 1 79  ? 88.818  116.924 101.513 1.00 47.69  ? 79  PRO B O   1 
ATOM   4622 C CB  . PRO B 1 79  ? 92.001  116.142 101.586 1.00 47.69  ? 79  PRO B CB  1 
ATOM   4623 C CG  . PRO B 1 79  ? 93.228  115.975 102.409 1.00 47.69  ? 79  PRO B CG  1 
ATOM   4624 C CD  . PRO B 1 79  ? 92.743  115.572 103.768 1.00 47.69  ? 79  PRO B CD  1 
ATOM   4625 N N   . SER B 1 80  ? 89.168  115.022 102.662 1.00 52.39  ? 80  SER B N   1 
ATOM   4626 C CA  . SER B 1 80  ? 87.871  114.465 102.296 1.00 52.39  ? 80  SER B CA  1 
ATOM   4627 C C   . SER B 1 80  ? 86.707  115.108 103.038 1.00 52.39  ? 80  SER B C   1 
ATOM   4628 O O   . SER B 1 80  ? 85.573  115.041 102.551 1.00 52.39  ? 80  SER B O   1 
ATOM   4629 C CB  . SER B 1 80  ? 87.858  112.956 102.546 1.00 52.39  ? 80  SER B CB  1 
ATOM   4630 O OG  . SER B 1 80  ? 88.653  112.274 101.595 1.00 52.39  ? 80  SER B OG  1 
ATOM   4631 N N   . PHE B 1 81  ? 86.958  115.725 104.196 1.00 47.86  ? 81  PHE B N   1 
ATOM   4632 C CA  . PHE B 1 81  ? 85.867  116.225 105.030 1.00 47.86  ? 81  PHE B CA  1 
ATOM   4633 C C   . PHE B 1 81  ? 85.105  117.349 104.336 1.00 47.86  ? 81  PHE B C   1 
ATOM   4634 O O   . PHE B 1 81  ? 83.870  117.323 104.262 1.00 47.86  ? 81  PHE B O   1 
ATOM   4635 C CB  . PHE B 1 81  ? 86.415  116.695 106.378 1.00 47.86  ? 81  PHE B CB  1 
ATOM   4636 C CG  . PHE B 1 81  ? 85.375  117.294 107.281 1.00 47.86  ? 81  PHE B CG  1 
ATOM   4637 C CD1 . PHE B 1 81  ? 84.213  116.603 107.578 1.00 47.86  ? 81  PHE B CD1 1 
ATOM   4638 C CD2 . PHE B 1 81  ? 85.562  118.549 107.837 1.00 47.86  ? 81  PHE B CD2 1 
ATOM   4639 C CE1 . PHE B 1 81  ? 83.255  117.154 108.409 1.00 47.86  ? 81  PHE B CE1 1 
ATOM   4640 C CE2 . PHE B 1 81  ? 84.608  119.103 108.669 1.00 47.86  ? 81  PHE B CE2 1 
ATOM   4641 C CZ  . PHE B 1 81  ? 83.454  118.406 108.955 1.00 47.86  ? 81  PHE B CZ  1 
ATOM   4642 N N   . ILE B 1 82  ? 85.825  118.344 103.817 1.00 51.61  ? 82  ILE B N   1 
ATOM   4643 C CA  . ILE B 1 82  ? 85.158  119.477 103.185 1.00 51.61  ? 82  ILE B CA  1 
ATOM   4644 C C   . ILE B 1 82  ? 84.486  119.050 101.881 1.00 51.61  ? 82  ILE B C   1 
ATOM   4645 O O   . ILE B 1 82  ? 83.404  119.541 101.541 1.00 51.61  ? 82  ILE B O   1 
ATOM   4646 C CB  . ILE B 1 82  ? 86.142  120.650 102.994 1.00 51.61  ? 82  ILE B CB  1 
ATOM   4647 C CG1 . ILE B 1 82  ? 85.379  121.973 102.892 1.00 51.61  ? 82  ILE B CG1 1 
ATOM   4648 C CG2 . ILE B 1 82  ? 87.067  120.449 101.795 1.00 51.61  ? 82  ILE B CG2 1 
ATOM   4649 C CD1 . ILE B 1 82  ? 84.820  122.456 104.213 1.00 51.61  ? 82  ILE B CD1 1 
ATOM   4650 N N   . SER B 1 83  ? 85.095  118.113 101.147 1.00 54.30  ? 83  SER B N   1 
ATOM   4651 C CA  . SER B 1 83  ? 84.479  117.629 99.917  1.00 54.30  ? 83  SER B CA  1 
ATOM   4652 C C   . SER B 1 83  ? 83.180  116.887 100.207 1.00 54.30  ? 83  SER B C   1 
ATOM   4653 O O   . SER B 1 83  ? 82.181  117.065 99.497  1.00 54.30  ? 83  SER B O   1 
ATOM   4654 C CB  . SER B 1 83  ? 85.453  116.728 99.159  1.00 54.30  ? 83  SER B CB  1 
ATOM   4655 O OG  . SER B 1 83  ? 84.763  115.851 98.289  1.00 54.30  ? 83  SER B OG  1 
ATOM   4656 N N   . SER B 1 84  ? 83.173  116.057 101.252 1.00 52.07  ? 84  SER B N   1 
ATOM   4657 C CA  . SER B 1 84  ? 81.951  115.361 101.636 1.00 52.07  ? 84  SER B CA  1 
ATOM   4658 C C   . SER B 1 84  ? 80.891  116.338 102.127 1.00 52.07  ? 84  SER B C   1 
ATOM   4659 O O   . SER B 1 84  ? 79.700  116.157 101.855 1.00 52.07  ? 84  SER B O   1 
ATOM   4660 C CB  . SER B 1 84  ? 82.258  114.319 102.707 1.00 52.07  ? 84  SER B CB  1 
ATOM   4661 O OG  . SER B 1 84  ? 81.352  113.232 102.634 1.00 52.07  ? 84  SER B OG  1 
ATOM   4662 N N   . MET B 1 85  ? 81.301  117.374 102.864 1.00 54.11  ? 85  MET B N   1 
ATOM   4663 C CA  . MET B 1 85  ? 80.341  118.378 103.308 1.00 54.11  ? 85  MET B CA  1 
ATOM   4664 C C   . MET B 1 85  ? 79.720  119.110 102.125 1.00 54.11  ? 85  MET B C   1 
ATOM   4665 O O   . MET B 1 85  ? 78.518  119.398 102.126 1.00 54.11  ? 85  MET B O   1 
ATOM   4666 C CB  . MET B 1 85  ? 81.013  119.366 104.261 1.00 54.11  ? 85  MET B CB  1 
ATOM   4667 C CG  . MET B 1 85  ? 80.965  118.945 105.719 1.00 54.11  ? 85  MET B CG  1 
ATOM   4668 S SD  . MET B 1 85  ? 79.340  118.338 106.207 1.00 54.11  ? 85  MET B SD  1 
ATOM   4669 C CE  . MET B 1 85  ? 79.455  118.449 107.991 1.00 54.11  ? 85  MET B CE  1 
ATOM   4670 N N   . LYS B 1 86  ? 80.523  119.421 101.107 1.00 56.68  ? 86  LYS B N   1 
ATOM   4671 C CA  . LYS B 1 86  ? 79.994  120.113 99.935  1.00 56.68  ? 86  LYS B CA  1 
ATOM   4672 C C   . LYS B 1 86  ? 79.056  119.220 99.130  1.00 56.68  ? 86  LYS B C   1 
ATOM   4673 O O   . LYS B 1 86  ? 77.946  119.633 98.775  1.00 56.68  ? 86  LYS B O   1 
ATOM   4674 C CB  . LYS B 1 86  ? 81.136  120.616 99.053  1.00 56.68  ? 86  LYS B CB  1 
ATOM   4675 C CG  . LYS B 1 86  ? 81.992  121.692 99.691  1.00 56.68  ? 86  LYS B CG  1 
ATOM   4676 C CD  . LYS B 1 86  ? 83.000  122.250 98.703  1.00 56.68  ? 86  LYS B CD  1 
ATOM   4677 C CE  . LYS B 1 86  ? 84.078  123.047 99.416  1.00 56.68  ? 86  LYS B CE  1 
ATOM   4678 N NZ  . LYS B 1 86  ? 83.495  124.089 100.303 1.00 56.68  ? 86  LYS B NZ  1 
ATOM   4679 N N   . LYS B 1 87  ? 79.481  117.992 98.828  1.00 62.75  ? 87  LYS B N   1 
ATOM   4680 C CA  . LYS B 1 87  ? 78.753  117.166 97.869  1.00 62.75  ? 87  LYS B CA  1 
ATOM   4681 C C   . LYS B 1 87  ? 77.793  116.180 98.527  1.00 62.75  ? 87  LYS B C   1 
ATOM   4682 O O   . LYS B 1 87  ? 76.611  116.147 98.172  1.00 62.75  ? 87  LYS B O   1 
ATOM   4683 C CB  . LYS B 1 87  ? 79.746  116.437 96.958  1.00 62.75  ? 87  LYS B CB  1 
ATOM   4684 C CG  . LYS B 1 87  ? 80.699  117.401 96.261  1.00 62.75  ? 87  LYS B CG  1 
ATOM   4685 C CD  . LYS B 1 87  ? 81.791  116.695 95.478  1.00 62.75  ? 87  LYS B CD  1 
ATOM   4686 C CE  . LYS B 1 87  ? 81.204  115.656 94.544  1.00 62.75  ? 87  LYS B CE  1 
ATOM   4687 N NZ  . LYS B 1 87  ? 80.512  116.288 93.386  1.00 62.75  ? 87  LYS B NZ  1 
ATOM   4688 N N   . PHE B 1 88  ? 78.268  115.366 99.468  1.00 58.65  ? 88  PHE B N   1 
ATOM   4689 C CA  . PHE B 1 88  ? 77.368  114.490 100.207 1.00 58.65  ? 88  PHE B CA  1 
ATOM   4690 C C   . PHE B 1 88  ? 76.413  115.309 101.066 1.00 58.65  ? 88  PHE B C   1 
ATOM   4691 O O   . PHE B 1 88  ? 76.759  116.386 101.559 1.00 58.65  ? 88  PHE B O   1 
ATOM   4692 C CB  . PHE B 1 88  ? 78.159  113.515 101.080 1.00 58.65  ? 88  PHE B CB  1 
ATOM   4693 C CG  . PHE B 1 88  ? 78.245  112.127 100.516 1.00 58.65  ? 88  PHE B CG  1 
ATOM   4694 C CD1 . PHE B 1 88  ? 77.097  111.441 100.158 1.00 58.65  ? 88  PHE B CD1 1 
ATOM   4695 C CD2 . PHE B 1 88  ? 79.470  111.505 100.350 1.00 58.65  ? 88  PHE B CD2 1 
ATOM   4696 C CE1 . PHE B 1 88  ? 77.171  110.163 99.642  1.00 58.65  ? 88  PHE B CE1 1 
ATOM   4697 C CE2 . PHE B 1 88  ? 79.549  110.227 99.832  1.00 58.65  ? 88  PHE B CE2 1 
ATOM   4698 C CZ  . PHE B 1 88  ? 78.398  109.556 99.480  1.00 58.65  ? 88  PHE B CZ  1 
ATOM   4699 N N   . GLY B 1 89  ? 75.198  114.796 101.236 1.00 59.30  ? 89  GLY B N   1 
ATOM   4700 C CA  . GLY B 1 89  ? 74.172  115.498 101.974 1.00 59.30  ? 89  GLY B CA  1 
ATOM   4701 C C   . GLY B 1 89  ? 74.360  115.422 103.479 1.00 59.30  ? 89  GLY B C   1 
ATOM   4702 O O   . GLY B 1 89  ? 75.309  114.839 104.003 1.00 59.30  ? 89  GLY B O   1 
ATOM   4703 N N   . ALA B 1 90  ? 73.414  116.043 104.189 1.00 61.08  ? 90  ALA B N   1 
ATOM   4704 C CA  . ALA B 1 90  ? 73.419  116.059 105.648 1.00 61.08  ? 90  ALA B CA  1 
ATOM   4705 C C   . ALA B 1 90  ? 72.976  114.736 106.258 1.00 61.08  ? 90  ALA B C   1 
ATOM   4706 O O   . ALA B 1 90  ? 73.032  114.591 107.487 1.00 61.08  ? 90  ALA B O   1 
ATOM   4707 C CB  . ALA B 1 90  ? 72.525  117.189 106.161 1.00 61.08  ? 90  ALA B CB  1 
ATOM   4708 N N   . LYS B 1 91  ? 72.530  113.780 105.437 1.00 60.31  ? 91  LYS B N   1 
ATOM   4709 C CA  . LYS B 1 91  ? 72.129  112.476 105.953 1.00 60.31  ? 91  LYS B CA  1 
ATOM   4710 C C   . LYS B 1 91  ? 73.286  111.765 106.643 1.00 60.31  ? 91  LYS B C   1 
ATOM   4711 O O   . LYS B 1 91  ? 73.064  110.970 107.565 1.00 60.31  ? 91  LYS B O   1 
ATOM   4712 C CB  . LYS B 1 91  ? 71.565  111.616 104.820 1.00 60.31  ? 91  LYS B CB  1 
ATOM   4713 C CG  . LYS B 1 91  ? 72.566  111.290 103.722 1.00 60.31  ? 91  LYS B CG  1 
ATOM   4714 C CD  . LYS B 1 91  ? 71.948  111.437 102.342 1.00 60.31  ? 91  LYS B CD  1 
ATOM   4715 C CE  . LYS B 1 91  ? 73.021  111.584 101.275 1.00 60.31  ? 91  LYS B CE  1 
ATOM   4716 N NZ  . LYS B 1 91  ? 72.442  111.798 99.921  1.00 60.31  ? 91  LYS B NZ  1 
ATOM   4717 N N   . ILE B 1 92  ? 74.523  112.051 106.227 1.00 53.97  ? 92  ILE B N   1 
ATOM   4718 C CA  . ILE B 1 92  ? 75.688  111.473 106.889 1.00 53.97  ? 92  ILE B CA  1 
ATOM   4719 C C   . ILE B 1 92  ? 75.758  111.930 108.339 1.00 53.97  ? 92  ILE B C   1 
ATOM   4720 O O   . ILE B 1 92  ? 75.969  111.121 109.247 1.00 53.97  ? 92  ILE B O   1 
ATOM   4721 C CB  . ILE B 1 92  ? 76.970  111.827 106.115 1.00 53.97  ? 92  ILE B CB  1 
ATOM   4722 C CG1 . ILE B 1 92  ? 76.938  111.200 104.720 1.00 53.97  ? 92  ILE B CG1 1 
ATOM   4723 C CG2 . ILE B 1 92  ? 78.201  111.364 106.872 1.00 53.97  ? 92  ILE B CG2 1 
ATOM   4724 C CD1 . ILE B 1 92  ? 76.730  109.699 104.730 1.00 53.97  ? 92  ILE B CD1 1 
ATOM   4725 N N   . VAL B 1 93  ? 75.557  113.227 108.583 1.00 52.53  ? 93  VAL B N   1 
ATOM   4726 C CA  . VAL B 1 93  ? 75.555  113.741 109.949 1.00 52.53  ? 93  VAL B CA  1 
ATOM   4727 C C   . VAL B 1 93  ? 74.338  113.225 110.713 1.00 52.53  ? 93  VAL B C   1 
ATOM   4728 O O   . VAL B 1 93  ? 74.421  112.910 111.911 1.00 52.53  ? 93  VAL B O   1 
ATOM   4729 C CB  . VAL B 1 93  ? 75.613  115.280 109.926 1.00 52.53  ? 93  VAL B CB  1 
ATOM   4730 C CG1 . VAL B 1 93  ? 75.392  115.865 111.315 1.00 52.53  ? 93  VAL B CG1 1 
ATOM   4731 C CG2 . VAL B 1 93  ? 76.937  115.746 109.337 1.00 52.53  ? 93  VAL B CG2 1 
ATOM   4732 N N   . TYR B 1 94  ? 73.195  113.126 110.028 1.00 55.82  ? 94  TYR B N   1 
ATOM   4733 C CA  . TYR B 1 94  ? 71.968  112.683 110.682 1.00 55.82  ? 94  TYR B CA  1 
ATOM   4734 C C   . TYR B 1 94  ? 72.095  111.248 111.182 1.00 55.82  ? 94  TYR B C   1 
ATOM   4735 O O   . TYR B 1 94  ? 71.611  110.915 112.272 1.00 55.82  ? 94  TYR B O   1 
ATOM   4736 C CB  . TYR B 1 94  ? 70.796  112.812 109.712 1.00 55.82  ? 94  TYR B CB  1 
ATOM   4737 C CG  . TYR B 1 94  ? 70.022  114.094 109.877 1.00 55.82  ? 94  TYR B CG  1 
ATOM   4738 C CD1 . TYR B 1 94  ? 70.487  115.274 109.313 1.00 55.82  ? 94  TYR B CD1 1 
ATOM   4739 C CD2 . TYR B 1 94  ? 68.839  114.133 110.600 1.00 55.82  ? 94  TYR B CD2 1 
ATOM   4740 C CE1 . TYR B 1 94  ? 69.793  116.457 109.457 1.00 55.82  ? 94  TYR B CE1 1 
ATOM   4741 C CE2 . TYR B 1 94  ? 68.137  115.314 110.751 1.00 55.82  ? 94  TYR B CE2 1 
ATOM   4742 C CZ  . TYR B 1 94  ? 68.620  116.473 110.176 1.00 55.82  ? 94  TYR B CZ  1 
ATOM   4743 O OH  . TYR B 1 94  ? 67.927  117.653 110.321 1.00 55.82  ? 94  TYR B OH  1 
ATOM   4744 N N   . ALA B 1 95  ? 72.751  110.387 110.398 1.00 51.89  ? 95  ALA B N   1 
ATOM   4745 C CA  . ALA B 1 95  ? 72.959  109.005 110.819 1.00 51.89  ? 95  ALA B CA  1 
ATOM   4746 C C   . ALA B 1 95  ? 73.825  108.926 112.072 1.00 51.89  ? 95  ALA B C   1 
ATOM   4747 O O   . ALA B 1 95  ? 73.545  108.131 112.977 1.00 51.89  ? 95  ALA B O   1 
ATOM   4748 C CB  . ALA B 1 95  ? 73.587  108.198 109.684 1.00 51.89  ? 95  ALA B CB  1 
ATOM   4749 N N   . THR B 1 96  ? 74.884  109.740 112.144 1.00 48.44  ? 96  THR B N   1 
ATOM   4750 C CA  . THR B 1 96  ? 75.717  109.751 113.344 1.00 48.44  ? 96  THR B CA  1 
ATOM   4751 C C   . THR B 1 96  ? 74.937  110.234 114.556 1.00 48.44  ? 96  THR B C   1 
ATOM   4752 O O   . THR B 1 96  ? 75.084  109.683 115.653 1.00 48.44  ? 96  THR B O   1 
ATOM   4753 C CB  . THR B 1 96  ? 76.949  110.631 113.146 1.00 48.44  ? 96  THR B CB  1 
ATOM   4754 O OG1 . THR B 1 96  ? 76.585  112.008 113.303 1.00 48.44  ? 96  THR B OG1 1 
ATOM   4755 C CG2 . THR B 1 96  ? 77.552  110.408 111.790 1.00 48.44  ? 96  THR B CG2 1 
ATOM   4756 N N   . LEU B 1 97  ? 74.112  111.270 114.381 1.00 48.30  ? 97  LEU B N   1 
ATOM   4757 C CA  . LEU B 1 97  ? 73.302  111.751 115.498 1.00 48.30  ? 97  LEU B CA  1 
ATOM   4758 C C   . LEU B 1 97  ? 72.350  110.668 115.992 1.00 48.30  ? 97  LEU B C   1 
ATOM   4759 O O   . LEU B 1 97  ? 72.204  110.459 117.206 1.00 48.30  ? 97  LEU B O   1 
ATOM   4760 C CB  . LEU B 1 97  ? 72.529  113.001 115.086 1.00 48.30  ? 97  LEU B CB  1 
ATOM   4761 C CG  . LEU B 1 97  ? 72.173  113.957 116.227 1.00 48.30  ? 97  LEU B CG  1 
ATOM   4762 C CD1 . LEU B 1 97  ? 73.399  114.705 116.734 1.00 48.30  ? 97  LEU B CD1 1 
ATOM   4763 C CD2 . LEU B 1 97  ? 71.083  114.923 115.792 1.00 48.30  ? 97  LEU B CD2 1 
ATOM   4764 N N   . ILE B 1 98  ? 71.718  109.949 115.061 1.00 44.91  ? 98  ILE B N   1 
ATOM   4765 C CA  . ILE B 1 98  ? 70.819  108.859 115.435 1.00 44.91  ? 98  ILE B CA  1 
ATOM   4766 C C   . ILE B 1 98  ? 71.579  107.770 116.186 1.00 44.91  ? 98  ILE B C   1 
ATOM   4767 O O   . ILE B 1 98  ? 71.113  107.267 117.217 1.00 44.91  ? 98  ILE B O   1 
ATOM   4768 C CB  . ILE B 1 98  ? 70.111  108.307 114.182 1.00 44.91  ? 98  ILE B CB  1 
ATOM   4769 C CG1 . ILE B 1 98  ? 68.966  109.233 113.769 1.00 44.91  ? 98  ILE B CG1 1 
ATOM   4770 C CG2 . ILE B 1 98  ? 69.587  106.904 114.426 1.00 44.91  ? 98  ILE B CG2 1 
ATOM   4771 C CD1 . ILE B 1 98  ? 68.252  108.792 112.513 1.00 44.91  ? 98  ILE B CD1 1 
ATOM   4772 N N   . PHE B 1 99  ? 72.764  107.400 115.690 1.00 41.78  ? 99  PHE B N   1 
ATOM   4773 C CA  . PHE B 1 99  ? 73.554  106.354 116.336 1.00 41.78  ? 99  PHE B CA  1 
ATOM   4774 C C   . PHE B 1 99  ? 73.966  106.761 117.745 1.00 41.78  ? 99  PHE B C   1 
ATOM   4775 O O   . PHE B 1 99  ? 73.905  105.948 118.675 1.00 41.78  ? 99  PHE B O   1 
ATOM   4776 C CB  . PHE B 1 99  ? 74.779  106.022 115.475 1.00 41.78  ? 99  PHE B CB  1 
ATOM   4777 C CG  . PHE B 1 99  ? 75.720  105.009 116.090 1.00 41.78  ? 99  PHE B CG  1 
ATOM   4778 C CD1 . PHE B 1 99  ? 76.721  105.397 116.970 1.00 41.78  ? 99  PHE B CD1 1 
ATOM   4779 C CD2 . PHE B 1 99  ? 75.598  103.665 115.784 1.00 41.78  ? 99  PHE B CD2 1 
ATOM   4780 C CE1 . PHE B 1 99  ? 77.577  104.467 117.527 1.00 41.78  ? 99  PHE B CE1 1 
ATOM   4781 C CE2 . PHE B 1 99  ? 76.453  102.730 116.340 1.00 41.78  ? 99  PHE B CE2 1 
ATOM   4782 C CZ  . PHE B 1 99  ? 77.442  103.133 117.212 1.00 41.78  ? 99  PHE B CZ  1 
ATOM   4783 N N   . LEU B 1 100 ? 74.399  108.011 117.922 1.00 43.21  ? 100 LEU B N   1 
ATOM   4784 C CA  . LEU B 1 100 ? 74.809  108.467 119.246 1.00 43.21  ? 100 LEU B CA  1 
ATOM   4785 C C   . LEU B 1 100 ? 73.636  108.477 120.217 1.00 43.21  ? 100 LEU B C   1 
ATOM   4786 O O   . LEU B 1 100 ? 73.774  108.053 121.372 1.00 43.21  ? 100 LEU B O   1 
ATOM   4787 C CB  . LEU B 1 100 ? 75.448  109.851 119.150 1.00 43.21  ? 100 LEU B CB  1 
ATOM   4788 C CG  . LEU B 1 100 ? 76.725  109.899 118.310 1.00 43.21  ? 100 LEU B CG  1 
ATOM   4789 C CD1 . LEU B 1 100 ? 77.381  111.254 118.407 1.00 43.21  ? 100 LEU B CD1 1 
ATOM   4790 C CD2 . LEU B 1 100 ? 77.694  108.804 118.732 1.00 43.21  ? 100 LEU B CD2 1 
ATOM   4791 N N   . VAL B 1 101 ? 72.468  108.942 119.764 1.00 42.40  ? 101 VAL B N   1 
ATOM   4792 C CA  . VAL B 1 101 ? 71.289  108.942 120.629 1.00 42.40  ? 101 VAL B CA  1 
ATOM   4793 C C   . VAL B 1 101 ? 70.919  107.515 121.025 1.00 42.40  ? 101 VAL B C   1 
ATOM   4794 O O   . VAL B 1 101 ? 70.627  107.234 122.198 1.00 42.40  ? 101 VAL B O   1 
ATOM   4795 C CB  . VAL B 1 101 ? 70.120  109.666 119.935 1.00 42.40  ? 101 VAL B CB  1 
ATOM   4796 C CG1 . VAL B 1 101 ? 68.807  109.364 120.636 1.00 42.40  ? 101 VAL B CG1 1 
ATOM   4797 C CG2 . VAL B 1 101 ? 70.374  111.163 119.903 1.00 42.40  ? 101 VAL B CG2 1 
ATOM   4798 N N   . SER B 1 102 ? 70.944  106.592 120.059 1.00 43.71  ? 102 SER B N   1 
ATOM   4799 C CA  . SER B 1 102 ? 70.600  105.203 120.350 1.00 43.71  ? 102 SER B CA  1 
ATOM   4800 C C   . SER B 1 102 ? 71.578  104.582 121.341 1.00 43.71  ? 102 SER B C   1 
ATOM   4801 O O   . SER B 1 102 ? 71.163  103.881 122.275 1.00 43.71  ? 102 SER B O   1 
ATOM   4802 C CB  . SER B 1 102 ? 70.567  104.394 119.054 1.00 43.71  ? 102 SER B CB  1 
ATOM   4803 O OG  . SER B 1 102 ? 70.586  103.003 119.320 1.00 43.71  ? 102 SER B OG  1 
ATOM   4804 N N   . ALA B 1 103 ? 72.878  104.830 121.157 1.00 43.16  ? 103 ALA B N   1 
ATOM   4805 C CA  . ALA B 1 103 ? 73.872  104.286 122.076 1.00 43.16  ? 103 ALA B CA  1 
ATOM   4806 C C   . ALA B 1 103 ? 73.685  104.841 123.481 1.00 43.16  ? 103 ALA B C   1 
ATOM   4807 O O   . ALA B 1 103 ? 73.770  104.097 124.466 1.00 43.16  ? 103 ALA B O   1 
ATOM   4808 C CB  . ALA B 1 103 ? 75.281  104.582 121.565 1.00 43.16  ? 103 ALA B CB  1 
ATOM   4809 N N   . PHE B 1 104 ? 73.414  106.146 123.589 1.00 44.41  ? 104 PHE B N   1 
ATOM   4810 C CA  . PHE B 1 104 ? 73.155  106.753 124.892 1.00 44.41  ? 104 PHE B CA  1 
ATOM   4811 C C   . PHE B 1 104 ? 71.972  106.091 125.587 1.00 44.41  ? 104 PHE B C   1 
ATOM   4812 O O   . PHE B 1 104 ? 72.059  105.710 126.763 1.00 44.41  ? 104 PHE B O   1 
ATOM   4813 C CB  . PHE B 1 104 ? 72.904  108.251 124.721 1.00 44.41  ? 104 PHE B CB  1 
ATOM   4814 C CG  . PHE B 1 104 ? 72.636  108.975 126.007 1.00 44.41  ? 104 PHE B CG  1 
ATOM   4815 C CD1 . PHE B 1 104 ? 73.574  108.981 127.022 1.00 44.41  ? 104 PHE B CD1 1 
ATOM   4816 C CD2 . PHE B 1 104 ? 71.441  109.644 126.202 1.00 44.41  ? 104 PHE B CD2 1 
ATOM   4817 C CE1 . PHE B 1 104 ? 73.328  109.646 128.208 1.00 44.41  ? 104 PHE B CE1 1 
ATOM   4818 C CE2 . PHE B 1 104 ? 71.188  110.310 127.384 1.00 44.41  ? 104 PHE B CE2 1 
ATOM   4819 C CZ  . PHE B 1 104 ? 72.133  110.311 128.390 1.00 44.41  ? 104 PHE B CZ  1 
ATOM   4820 N N   . ILE B 1 105 ? 70.860  105.930 124.863 1.00 43.21  ? 105 ILE B N   1 
ATOM   4821 C CA  . ILE B 1 105 ? 69.651  105.373 125.470 1.00 43.21  ? 105 ILE B CA  1 
ATOM   4822 C C   . ILE B 1 105 ? 69.886  103.933 125.912 1.00 43.21  ? 105 ILE B C   1 
ATOM   4823 O O   . ILE B 1 105 ? 69.527  103.543 127.033 1.00 43.21  ? 105 ILE B O   1 
ATOM   4824 C CB  . ILE B 1 105 ? 68.461  105.483 124.501 1.00 43.21  ? 105 ILE B CB  1 
ATOM   4825 C CG1 . ILE B 1 105 ? 68.132  106.951 124.227 1.00 43.21  ? 105 ILE B CG1 1 
ATOM   4826 C CG2 . ILE B 1 105 ? 67.248  104.761 125.061 1.00 43.21  ? 105 ILE B CG2 1 
ATOM   4827 C CD1 . ILE B 1 105 ? 66.916  107.152 123.351 1.00 43.21  ? 105 ILE B CD1 1 
ATOM   4828 N N   . VAL B 1 106 ? 70.502  103.124 125.044 1.00 44.60  ? 106 VAL B N   1 
ATOM   4829 C CA  . VAL B 1 106 ? 70.710  101.714 125.367 1.00 44.60  ? 106 VAL B CA  1 
ATOM   4830 C C   . VAL B 1 106 ? 71.661  101.563 126.550 1.00 44.60  ? 106 VAL B C   1 
ATOM   4831 O O   . VAL B 1 106 ? 71.432  100.738 127.446 1.00 44.60  ? 106 VAL B O   1 
ATOM   4832 C CB  . VAL B 1 106 ? 71.212  100.949 124.128 1.00 44.60  ? 106 VAL B CB  1 
ATOM   4833 C CG1 . VAL B 1 106 ? 71.586  99.527  124.498 1.00 44.60  ? 106 VAL B CG1 1 
ATOM   4834 C CG2 . VAL B 1 106 ? 70.141  100.936 123.055 1.00 44.60  ? 106 VAL B CG2 1 
ATOM   4835 N N   . ALA B 1 107 ? 72.742  102.351 126.577 1.00 50.84  ? 107 ALA B N   1 
ATOM   4836 C CA  . ALA B 1 107 ? 73.690  102.256 127.679 1.00 50.84  ? 107 ALA B CA  1 
ATOM   4837 C C   . ALA B 1 107 ? 73.052  102.668 128.998 1.00 50.84  ? 107 ALA B C   1 
ATOM   4838 O O   . ALA B 1 107 ? 73.240  101.995 130.021 1.00 50.84  ? 107 ALA B O   1 
ATOM   4839 C CB  . ALA B 1 107 ? 74.923  103.107 127.383 1.00 50.84  ? 107 ALA B CB  1 
ATOM   4840 N N   . TYR B 1 108 ? 72.278  103.758 128.992 1.00 56.59  ? 108 TYR B N   1 
ATOM   4841 C CA  . TYR B 1 108 ? 71.597  104.179 130.211 1.00 56.59  ? 108 TYR B CA  1 
ATOM   4842 C C   . TYR B 1 108 ? 70.630  103.106 130.695 1.00 56.59  ? 108 TYR B C   1 
ATOM   4843 O O   . TYR B 1 108 ? 70.585  102.788 131.890 1.00 56.59  ? 108 TYR B O   1 
ATOM   4844 C CB  . TYR B 1 108 ? 70.866  105.501 129.979 1.00 56.59  ? 108 TYR B CB  1 
ATOM   4845 C CG  . TYR B 1 108 ? 70.365  106.142 131.251 1.00 56.59  ? 108 TYR B CG  1 
ATOM   4846 C CD1 . TYR B 1 108 ? 71.241  106.488 132.268 1.00 56.59  ? 108 TYR B CD1 1 
ATOM   4847 C CD2 . TYR B 1 108 ? 69.013  106.395 131.435 1.00 56.59  ? 108 TYR B CD2 1 
ATOM   4848 C CE1 . TYR B 1 108 ? 70.787  107.070 133.435 1.00 56.59  ? 108 TYR B CE1 1 
ATOM   4849 C CE2 . TYR B 1 108 ? 68.548  106.978 132.599 1.00 56.59  ? 108 TYR B CE2 1 
ATOM   4850 C CZ  . TYR B 1 108 ? 69.440  107.313 133.594 1.00 56.59  ? 108 TYR B CZ  1 
ATOM   4851 O OH  . TYR B 1 108 ? 68.982  107.894 134.754 1.00 56.59  ? 108 TYR B OH  1 
ATOM   4852 N N   . ALA B 1 109 ? 69.862  102.518 129.772 1.00 56.68  ? 109 ALA B N   1 
ATOM   4853 C CA  . ALA B 1 109 ? 68.887  101.504 130.159 1.00 56.68  ? 109 ALA B CA  1 
ATOM   4854 C C   . ALA B 1 109 ? 69.563  100.272 130.751 1.00 56.68  ? 109 ALA B C   1 
ATOM   4855 O O   . ALA B 1 109 ? 69.141  99.774  131.802 1.00 56.68  ? 109 ALA B O   1 
ATOM   4856 C CB  . ALA B 1 109 ? 68.028  101.118 128.956 1.00 56.68  ? 109 ALA B CB  1 
ATOM   4857 N N   . CYS B 1 110 ? 70.619  99.776  130.101 1.00 59.00  ? 110 CYS B N   1 
ATOM   4858 C CA  . CYS B 1 110 ? 71.294  98.582  130.603 1.00 59.00  ? 110 CYS B CA  1 
ATOM   4859 C C   . CYS B 1 110 ? 71.951  98.841  131.954 1.00 59.00  ? 110 CYS B C   1 
ATOM   4860 O O   . CYS B 1 110 ? 71.845  98.013  132.873 1.00 59.00  ? 110 CYS B O   1 
ATOM   4861 C CB  . CYS B 1 110 ? 72.330  98.097  129.590 1.00 59.00  ? 110 CYS B CB  1 
ATOM   4862 N N   . PHE B 1 111 ? 72.618  99.990  132.102 1.00 57.88  ? 111 PHE B N   1 
ATOM   4863 C CA  . PHE B 1 111 ? 73.294  100.289 133.359 1.00 57.88  ? 111 PHE B CA  1 
ATOM   4864 C C   . PHE B 1 111 ? 72.296  100.474 134.493 1.00 57.88  ? 111 PHE B C   1 
ATOM   4865 O O   . PHE B 1 111 ? 72.549  100.038 135.621 1.00 57.88  ? 111 PHE B O   1 
ATOM   4866 C CB  . PHE B 1 111 ? 74.173  101.527 133.196 1.00 57.88  ? 111 PHE B CB  1 
ATOM   4867 C CG  . PHE B 1 111 ? 75.416  101.284 132.386 1.00 57.88  ? 111 PHE B CG  1 
ATOM   4868 C CD1 . PHE B 1 111 ? 75.844  99.995  132.107 1.00 57.88  ? 111 PHE B CD1 1 
ATOM   4869 C CD2 . PHE B 1 111 ? 76.150  102.346 131.892 1.00 57.88  ? 111 PHE B CD2 1 
ATOM   4870 C CE1 . PHE B 1 111 ? 76.985  99.775  131.359 1.00 57.88  ? 111 PHE B CE1 1 
ATOM   4871 C CE2 . PHE B 1 111 ? 77.287  102.131 131.139 1.00 57.88  ? 111 PHE B CE2 1 
ATOM   4872 C CZ  . PHE B 1 111 ? 77.707  100.846 130.876 1.00 57.88  ? 111 PHE B CZ  1 
ATOM   4873 N N   . LYS B 1 112 ? 71.152  101.106 134.218 1.00 66.79  ? 112 LYS B N   1 
ATOM   4874 C CA  . LYS B 1 112 ? 70.138  101.244 135.257 1.00 66.79  ? 112 LYS B CA  1 
ATOM   4875 C C   . LYS B 1 112 ? 69.519  99.897  135.613 1.00 66.79  ? 112 LYS B C   1 
ATOM   4876 O O   . LYS B 1 112 ? 69.244  99.630  136.789 1.00 66.79  ? 112 LYS B O   1 
ATOM   4877 C CB  . LYS B 1 112 ? 69.061  102.233 134.814 1.00 66.79  ? 112 LYS B CB  1 
ATOM   4878 C CG  . LYS B 1 112 ? 68.106  102.631 135.925 1.00 66.79  ? 112 LYS B CG  1 
ATOM   4879 C CD  . LYS B 1 112 ? 67.209  103.777 135.497 1.00 66.79  ? 112 LYS B CD  1 
ATOM   4880 C CE  . LYS B 1 112 ? 66.266  104.180 136.617 1.00 66.79  ? 112 LYS B CE  1 
ATOM   4881 N NZ  . LYS B 1 112 ? 65.420  105.342 136.232 1.00 66.79  ? 112 LYS B NZ  1 
ATOM   4882 N N   . MET B 1 113 ? 69.296  99.032  134.619 1.00 68.98  ? 113 MET B N   1 
ATOM   4883 C CA  . MET B 1 113 ? 68.640  97.759  134.902 1.00 68.98  ? 113 MET B CA  1 
ATOM   4884 C C   . MET B 1 113 ? 69.561  96.793  135.640 1.00 68.98  ? 113 MET B C   1 
ATOM   4885 O O   . MET B 1 113 ? 69.076  95.916  136.362 1.00 68.98  ? 113 MET B O   1 
ATOM   4886 C CB  . MET B 1 113 ? 68.116  97.131  133.608 1.00 68.98  ? 113 MET B CB  1 
ATOM   4887 C CG  . MET B 1 113 ? 69.061  96.149  132.935 1.00 68.98  ? 113 MET B CG  1 
ATOM   4888 S SD  . MET B 1 113 ? 68.239  95.085  131.734 1.00 68.98  ? 113 MET B SD  1 
ATOM   4889 C CE  . MET B 1 113 ? 67.533  96.307  130.631 1.00 68.98  ? 113 MET B CE  1 
ATOM   4890 N N   . PHE B 1 114 ? 70.880  96.926  135.480 1.00 68.67  ? 114 PHE B N   1 
ATOM   4891 C CA  . PHE B 1 114 ? 71.802  96.044  136.189 1.00 68.67  ? 114 PHE B CA  1 
ATOM   4892 C C   . PHE B 1 114 ? 72.549  96.713  137.337 1.00 68.67  ? 114 PHE B C   1 
ATOM   4893 O O   . PHE B 1 114 ? 73.379  96.051  137.972 1.00 68.67  ? 114 PHE B O   1 
ATOM   4894 C CB  . PHE B 1 114 ? 72.804  95.418  135.210 1.00 68.67  ? 114 PHE B CB  1 
ATOM   4895 C CG  . PHE B 1 114 ? 72.227  94.290  134.398 1.00 68.67  ? 114 PHE B CG  1 
ATOM   4896 C CD1 . PHE B 1 114 ? 71.798  93.129  135.019 1.00 68.67  ? 114 PHE B CD1 1 
ATOM   4897 C CD2 . PHE B 1 114 ? 72.112  94.389  133.023 1.00 68.67  ? 114 PHE B CD2 1 
ATOM   4898 C CE1 . PHE B 1 114 ? 71.266  92.086  134.285 1.00 68.67  ? 114 PHE B CE1 1 
ATOM   4899 C CE2 . PHE B 1 114 ? 71.579  93.347  132.281 1.00 68.67  ? 114 PHE B CE2 1 
ATOM   4900 C CZ  . PHE B 1 114 ? 71.158  92.196  132.914 1.00 68.67  ? 114 PHE B CZ  1 
ATOM   4901 N N   . HIS B 1 115 ? 72.264  97.985  137.635 1.00 70.44  ? 115 HIS B N   1 
ATOM   4902 C CA  . HIS B 1 115 ? 72.896  98.712  138.744 1.00 70.44  ? 115 HIS B CA  1 
ATOM   4903 C C   . HIS B 1 115 ? 74.420  98.678  138.645 1.00 70.44  ? 115 HIS B C   1 
ATOM   4904 O O   . HIS B 1 115 ? 75.121  98.462  139.635 1.00 70.44  ? 115 HIS B O   1 
ATOM   4905 C CB  . HIS B 1 115 ? 72.433  98.179  140.104 1.00 70.44  ? 115 HIS B CB  1 
ATOM   4906 C CG  . HIS B 1 115 ? 70.955  97.959  140.198 1.00 70.44  ? 115 HIS B CG  1 
ATOM   4907 N ND1 . HIS B 1 115 ? 70.399  96.715  140.406 1.00 70.44  ? 115 HIS B ND1 1 
ATOM   4908 C CD2 . HIS B 1 115 ? 69.917  98.825  140.114 1.00 70.44  ? 115 HIS B CD2 1 
ATOM   4909 C CE1 . HIS B 1 115 ? 69.084  96.824  140.447 1.00 70.44  ? 115 HIS B CE1 1 
ATOM   4910 N NE2 . HIS B 1 115 ? 68.765  98.093  140.271 1.00 70.44  ? 115 HIS B NE2 1 
ATOM   4911 N N   . ILE B 1 116 ? 74.937  98.887  137.435 1.00 62.93  ? 116 ILE B N   1 
ATOM   4912 C CA  . ILE B 1 116 ? 76.376  98.839  137.211 1.00 62.93  ? 116 ILE B CA  1 
ATOM   4913 C C   . ILE B 1 116 ? 77.021  100.083 137.809 1.00 62.93  ? 116 ILE B C   1 
ATOM   4914 O O   . ILE B 1 116 ? 76.553  101.210 137.592 1.00 62.93  ? 116 ILE B O   1 
ATOM   4915 C CB  . ILE B 1 116 ? 76.674  98.704  135.709 1.00 62.93  ? 116 ILE B CB  1 
ATOM   4916 C CG1 . ILE B 1 116 ? 76.572  97.239  135.278 1.00 62.93  ? 116 ILE B CG1 1 
ATOM   4917 C CG2 . ILE B 1 116 ? 78.049  99.244  135.367 1.00 62.93  ? 116 ILE B CG2 1 
ATOM   4918 C CD1 . ILE B 1 116 ? 77.512  96.317  136.020 1.00 62.93  ? 116 ILE B CD1 1 
ATOM   4919 N N   . GLY B 1 117 ? 78.094  99.885  138.576 1.00 58.88  ? 117 GLY B N   1 
ATOM   4920 C CA  . GLY B 1 117 ? 78.801  100.974 139.209 1.00 58.88  ? 117 GLY B CA  1 
ATOM   4921 C C   . GLY B 1 117 ? 79.457  101.897 138.203 1.00 58.88  ? 117 GLY B C   1 
ATOM   4922 O O   . GLY B 1 117 ? 79.642  101.541 137.038 1.00 58.88  ? 117 GLY B O   1 
ATOM   4923 N N   . PRO B 1 118 ? 79.783  103.122 138.626 1.00 56.16  ? 118 PRO B N   1 
ATOM   4924 C CA  . PRO B 1 118 ? 80.336  104.104 137.674 1.00 56.16  ? 118 PRO B CA  1 
ATOM   4925 C C   . PRO B 1 118 ? 81.655  103.699 137.030 1.00 56.16  ? 118 PRO B C   1 
ATOM   4926 O O   . PRO B 1 118 ? 81.865  103.989 135.848 1.00 56.16  ? 118 PRO B O   1 
ATOM   4927 C CB  . PRO B 1 118 ? 80.486  105.368 138.533 1.00 56.16  ? 118 PRO B CB  1 
ATOM   4928 C CG  . PRO B 1 118 ? 80.529  104.871 139.940 1.00 56.16  ? 118 PRO B CG  1 
ATOM   4929 C CD  . PRO B 1 118 ? 79.617  103.690 139.972 1.00 56.16  ? 118 PRO B CD  1 
ATOM   4930 N N   . GLY B 1 119 ? 82.552  103.041 137.765 1.00 52.76  ? 119 GLY B N   1 
ATOM   4931 C CA  . GLY B 1 119 ? 83.813  102.623 137.166 1.00 52.76  ? 119 GLY B CA  1 
ATOM   4932 C C   . GLY B 1 119 ? 83.623  101.563 136.097 1.00 52.76  ? 119 GLY B C   1 
ATOM   4933 O O   . GLY B 1 119 ? 84.209  101.638 135.010 1.00 52.76  ? 119 GLY B O   1 
ATOM   4934 N N   . ILE B 1 120 ? 82.788  100.565 136.392 1.00 50.40  ? 120 ILE B N   1 
ATOM   4935 C CA  . ILE B 1 120 ? 82.470  99.543  135.405 1.00 50.40  ? 120 ILE B CA  1 
ATOM   4936 C C   . ILE B 1 120 ? 81.730  100.159 134.230 1.00 50.40  ? 120 ILE B C   1 
ATOM   4937 O O   . ILE B 1 120 ? 81.913  99.747  133.081 1.00 50.40  ? 120 ILE B O   1 
ATOM   4938 C CB  . ILE B 1 120 ? 81.655  98.413  136.060 1.00 50.40  ? 120 ILE B CB  1 
ATOM   4939 C CG1 . ILE B 1 120 ? 82.375  97.898  137.306 1.00 50.40  ? 120 ILE B CG1 1 
ATOM   4940 C CG2 . ILE B 1 120 ? 81.422  97.274  135.079 1.00 50.40  ? 120 ILE B CG2 1 
ATOM   4941 C CD1 . ILE B 1 120 ? 81.580  96.886  138.089 1.00 50.40  ? 120 ILE B CD1 1 
ATOM   4942 N N   . ALA B 1 121 ? 80.891  101.163 134.496 1.00 52.13  ? 121 ALA B N   1 
ATOM   4943 C CA  . ALA B 1 121 ? 80.187  101.851 133.420 1.00 52.13  ? 121 ALA B CA  1 
ATOM   4944 C C   . ALA B 1 121 ? 81.160  102.566 132.492 1.00 52.13  ? 121 ALA B C   1 
ATOM   4945 O O   . ALA B 1 121 ? 81.028  102.493 131.264 1.00 52.13  ? 121 ALA B O   1 
ATOM   4946 C CB  . ALA B 1 121 ? 79.181  102.840 134.008 1.00 52.13  ? 121 ALA B CB  1 
ATOM   4947 N N   . ALA B 1 122 ? 82.151  103.254 133.064 1.00 44.13  ? 122 ALA B N   1 
ATOM   4948 C CA  . ALA B 1 122 ? 83.160  103.922 132.249 1.00 44.13  ? 122 ALA B CA  1 
ATOM   4949 C C   . ALA B 1 122 ? 83.958  102.916 131.430 1.00 44.13  ? 122 ALA B C   1 
ATOM   4950 O O   . ALA B 1 122 ? 84.223  103.141 130.241 1.00 44.13  ? 122 ALA B O   1 
ATOM   4951 C CB  . ALA B 1 122 ? 84.089  104.751 133.134 1.00 44.13  ? 122 ALA B CB  1 
ATOM   4952 N N   . GLY B 1 123 ? 84.335  101.795 132.045 1.00 44.42  ? 123 GLY B N   1 
ATOM   4953 C CA  . GLY B 1 123 ? 85.056  100.771 131.306 1.00 44.42  ? 123 GLY B CA  1 
ATOM   4954 C C   . GLY B 1 123 ? 84.237  100.173 130.176 1.00 44.42  ? 123 GLY B C   1 
ATOM   4955 O O   . GLY B 1 123 ? 84.745  99.965  129.070 1.00 44.42  ? 123 GLY B O   1 
ATOM   4956 N N   . ILE B 1 124 ? 82.956  99.896  130.435 1.00 42.39  ? 124 ILE B N   1 
ATOM   4957 C CA  . ILE B 1 124 ? 82.088  99.322  129.411 1.00 42.39  ? 124 ILE B CA  1 
ATOM   4958 C C   . ILE B 1 124 ? 81.895  100.300 128.262 1.00 42.39  ? 124 ILE B C   1 
ATOM   4959 O O   . ILE B 1 124 ? 81.892  99.905  127.093 1.00 42.39  ? 124 ILE B O   1 
ATOM   4960 C CB  . ILE B 1 124 ? 80.744  98.885  130.025 1.00 42.39  ? 124 ILE B CB  1 
ATOM   4961 C CG1 . ILE B 1 124 ? 80.944  97.673  130.936 1.00 42.39  ? 124 ILE B CG1 1 
ATOM   4962 C CG2 . ILE B 1 124 ? 79.725  98.565  128.944 1.00 42.39  ? 124 ILE B CG2 1 
ATOM   4963 C CD1 . ILE B 1 124 ? 81.134  96.373  130.188 1.00 42.39  ? 124 ILE B CD1 1 
ATOM   4964 N N   . ILE B 1 125 ? 81.730  101.589 128.568 1.00 39.35  ? 125 ILE B N   1 
ATOM   4965 C CA  . ILE B 1 125 ? 81.615  102.583 127.502 1.00 39.35  ? 125 ILE B CA  1 
ATOM   4966 C C   . ILE B 1 125 ? 82.892  102.619 126.673 1.00 39.35  ? 125 ILE B C   1 
ATOM   4967 O O   . ILE B 1 125 ? 82.852  102.523 125.438 1.00 39.35  ? 125 ILE B O   1 
ATOM   4968 C CB  . ILE B 1 125 ? 81.290  103.966 128.094 1.00 39.35  ? 125 ILE B CB  1 
ATOM   4969 C CG1 . ILE B 1 125 ? 79.860  103.998 128.629 1.00 39.35  ? 125 ILE B CG1 1 
ATOM   4970 C CG2 . ILE B 1 125 ? 81.505  105.060 127.060 1.00 39.35  ? 125 ILE B CG2 1 
ATOM   4971 C CD1 . ILE B 1 125 ? 78.816  103.686 127.588 1.00 39.35  ? 125 ILE B CD1 1 
ATOM   4972 N N   . ALA B 1 126 ? 84.047  102.688 127.344 1.00 37.21  ? 126 ALA B N   1 
ATOM   4973 C CA  . ALA B 1 126 ? 85.322  102.801 126.643 1.00 37.21  ? 126 ALA B CA  1 
ATOM   4974 C C   . ALA B 1 126 ? 85.635  101.560 125.824 1.00 37.21  ? 126 ALA B C   1 
ATOM   4975 O O   . ALA B 1 126 ? 86.385  101.640 124.845 1.00 37.21  ? 126 ALA B O   1 
ATOM   4976 C CB  . ALA B 1 126 ? 86.449  103.067 127.640 1.00 37.21  ? 126 ALA B CB  1 
ATOM   4977 N N   . GLY B 1 127 ? 85.085  100.412 126.203 1.00 39.60  ? 127 GLY B N   1 
ATOM   4978 C CA  . GLY B 1 127 ? 85.324  99.207  125.437 1.00 39.60  ? 127 GLY B CA  1 
ATOM   4979 C C   . GLY B 1 127 ? 84.325  98.980  124.319 1.00 39.60  ? 127 GLY B C   1 
ATOM   4980 O O   . GLY B 1 127 ? 84.719  98.770  123.169 1.00 39.60  ? 127 GLY B O   1 
ATOM   4981 N N   . GLY B 1 128 ? 83.032  99.000  124.648 1.00 38.26  ? 128 GLY B N   1 
ATOM   4982 C CA  . GLY B 1 128 ? 82.014  98.752  123.640 1.00 38.26  ? 128 GLY B CA  1 
ATOM   4983 C C   . GLY B 1 128 ? 82.001  99.813  122.561 1.00 38.26  ? 128 GLY B C   1 
ATOM   4984 O O   . GLY B 1 128 ? 81.945  99.506  121.370 1.00 38.26  ? 128 GLY B O   1 
ATOM   4985 N N   . LEU B 1 129 ? 82.051  101.078 122.961 1.00 39.39  ? 129 LEU B N   1 
ATOM   4986 C CA  . LEU B 1 129 ? 82.228  102.164 122.008 1.00 39.39  ? 129 LEU B CA  1 
ATOM   4987 C C   . LEU B 1 129 ? 83.726  102.427 121.932 1.00 39.39  ? 129 LEU B C   1 
ATOM   4988 O O   . LEU B 1 129 ? 84.306  103.040 122.834 1.00 39.39  ? 129 LEU B O   1 
ATOM   4989 C CB  . LEU B 1 129 ? 81.428  103.391 122.432 1.00 39.39  ? 129 LEU B CB  1 
ATOM   4990 C CG  . LEU B 1 129 ? 79.933  103.120 122.651 1.00 39.39  ? 129 LEU B CG  1 
ATOM   4991 C CD1 . LEU B 1 129 ? 79.152  104.412 122.747 1.00 39.39  ? 129 LEU B CD1 1 
ATOM   4992 C CD2 . LEU B 1 129 ? 79.355  102.247 121.544 1.00 39.39  ? 129 LEU B CD2 1 
ATOM   4993 N N   . THR B 1 130 ? 84.356  101.954 120.855 1.00 36.18  ? 130 THR B N   1 
ATOM   4994 C CA  . THR B 1 130 ? 85.806  101.809 120.823 1.00 36.18  ? 130 THR B CA  1 
ATOM   4995 C C   . THR B 1 130 ? 86.496  103.165 120.778 1.00 36.18  ? 130 THR B C   1 
ATOM   4996 O O   . THR B 1 130 ? 86.860  103.655 119.704 1.00 36.18  ? 130 THR B O   1 
ATOM   4997 C CB  . THR B 1 130 ? 86.232  100.955 119.627 1.00 36.18  ? 130 THR B CB  1 
ATOM   4998 O OG1 . THR B 1 130 ? 85.338  99.844  119.492 1.00 36.18  ? 130 THR B OG1 1 
ATOM   4999 C CG2 . THR B 1 130 ? 87.645  100.433 119.822 1.00 36.18  ? 130 THR B CG2 1 
ATOM   5000 N N   . GLN B 1 131 ? 86.676  103.772 121.947 1.00 37.43  ? 131 GLN B N   1 
ATOM   5001 C CA  . GLN B 1 131 ? 87.324  105.067 122.080 1.00 37.43  ? 131 GLN B CA  1 
ATOM   5002 C C   . GLN B 1 131 ? 88.291  105.001 123.252 1.00 37.43  ? 131 GLN B C   1 
ATOM   5003 O O   . GLN B 1 131 ? 87.922  104.540 124.338 1.00 37.43  ? 131 GLN B O   1 
ATOM   5004 C CB  . GLN B 1 131 ? 86.288  106.176 122.288 1.00 37.43  ? 131 GLN B CB  1 
ATOM   5005 C CG  . GLN B 1 131 ? 86.879  107.537 122.586 1.00 37.43  ? 131 GLN B CG  1 
ATOM   5006 C CD  . GLN B 1 131 ? 87.062  108.368 121.332 1.00 37.43  ? 131 GLN B CD  1 
ATOM   5007 O OE1 . GLN B 1 131 ? 87.112  107.835 120.224 1.00 37.43  ? 131 GLN B OE1 1 
ATOM   5008 N NE2 . GLN B 1 131 ? 87.163  109.680 121.500 1.00 37.43  ? 131 GLN B NE2 1 
ATOM   5009 N N   . SER B 1 132 ? 89.525  105.454 123.033 1.00 36.85  ? 132 SER B N   1 
ATOM   5010 C CA  . SER B 1 132 ? 90.579  105.285 124.027 1.00 36.85  ? 132 SER B CA  1 
ATOM   5011 C C   . SER B 1 132 ? 90.749  106.486 124.946 1.00 36.85  ? 132 SER B C   1 
ATOM   5012 O O   . SER B 1 132 ? 91.240  106.326 126.069 1.00 36.85  ? 132 SER B O   1 
ATOM   5013 C CB  . SER B 1 132 ? 91.907  104.982 123.331 1.00 36.85  ? 132 SER B CB  1 
ATOM   5014 O OG  . SER B 1 132 ? 91.706  104.183 122.179 1.00 36.85  ? 132 SER B OG  1 
ATOM   5015 N N   . ALA B 1 133 ? 90.363  107.686 124.508 1.00 35.93  ? 133 ALA B N   1 
ATOM   5016 C CA  . ALA B 1 133 ? 90.478  108.867 125.358 1.00 35.93  ? 133 ALA B CA  1 
ATOM   5017 C C   . ALA B 1 133 ? 89.508  108.843 126.532 1.00 35.93  ? 133 ALA B C   1 
ATOM   5018 O O   . ALA B 1 133 ? 89.654  109.654 127.459 1.00 35.93  ? 133 ALA B O   1 
ATOM   5019 C CB  . ALA B 1 133 ? 90.259  110.133 124.531 1.00 35.93  ? 133 ALA B CB  1 
ATOM   5020 N N   . VAL B 1 134 ? 88.532  107.931 126.510 1.00 40.15  ? 134 VAL B N   1 
ATOM   5021 C CA  . VAL B 1 134 ? 87.578  107.812 127.606 1.00 40.15  ? 134 VAL B CA  1 
ATOM   5022 C C   . VAL B 1 134 ? 88.298  107.462 128.903 1.00 40.15  ? 134 VAL B C   1 
ATOM   5023 O O   . VAL B 1 134 ? 87.921  107.937 129.976 1.00 40.15  ? 134 VAL B O   1 
ATOM   5024 C CB  . VAL B 1 134 ? 86.490  106.778 127.258 1.00 40.15  ? 134 VAL B CB  1 
ATOM   5025 C CG1 . VAL B 1 134 ? 85.534  106.584 128.424 1.00 40.15  ? 134 VAL B CG1 1 
ATOM   5026 C CG2 . VAL B 1 134 ? 85.724  107.217 126.024 1.00 40.15  ? 134 VAL B CG2 1 
ATOM   5027 N N   . ILE B 1 135 ? 89.349  106.641 128.823 1.00 45.29  ? 135 ILE B N   1 
ATOM   5028 C CA  . ILE B 1 135 ? 90.080  106.246 130.027 1.00 45.29  ? 135 ILE B CA  1 
ATOM   5029 C C   . ILE B 1 135 ? 90.679  107.466 130.717 1.00 45.29  ? 135 ILE B C   1 
ATOM   5030 O O   . ILE B 1 135 ? 90.467  107.689 131.915 1.00 45.29  ? 135 ILE B O   1 
ATOM   5031 C CB  . ILE B 1 135 ? 91.164  105.211 129.682 1.00 45.29  ? 135 ILE B CB  1 
ATOM   5032 C CG1 . ILE B 1 135 ? 90.529  103.919 129.172 1.00 45.29  ? 135 ILE B CG1 1 
ATOM   5033 C CG2 . ILE B 1 135 ? 92.049  104.936 130.886 1.00 45.29  ? 135 ILE B CG2 1 
ATOM   5034 C CD1 . ILE B 1 135 ? 91.427  103.137 128.249 1.00 45.29  ? 135 ILE B CD1 1 
ATOM   5035 N N   . GLY B 1 136 ? 91.412  108.289 129.964 1.00 50.81  ? 136 GLY B N   1 
ATOM   5036 C CA  . GLY B 1 136 ? 92.030  109.465 130.557 1.00 50.81  ? 136 GLY B CA  1 
ATOM   5037 C C   . GLY B 1 136 ? 91.018  110.491 131.028 1.00 50.81  ? 136 GLY B C   1 
ATOM   5038 O O   . GLY B 1 136 ? 91.160  111.065 132.116 1.00 50.81  ? 136 GLY B O   1 
ATOM   5039 N N   . SER B 1 137 ? 89.978  110.733 130.221 1.00 51.85  ? 137 SER B N   1 
ATOM   5040 C CA  . SER B 1 137 ? 88.964  111.708 130.612 1.00 51.85  ? 137 SER B CA  1 
ATOM   5041 C C   . SER B 1 137 ? 88.220  111.256 131.863 1.00 51.85  ? 137 SER B C   1 
ATOM   5042 O O   . SER B 1 137 ? 87.950  112.065 132.760 1.00 51.85  ? 137 SER B O   1 
ATOM   5043 C CB  . SER B 1 137 ? 87.991  111.938 129.458 1.00 51.85  ? 137 SER B CB  1 
ATOM   5044 O OG  . SER B 1 137 ? 86.948  112.815 129.841 1.00 51.85  ? 137 SER B OG  1 
ATOM   5045 N N   . SER B 1 138 ? 87.904  109.963 131.951 1.00 55.92  ? 138 SER B N   1 
ATOM   5046 C CA  . SER B 1 138 ? 87.223  109.424 133.118 1.00 55.92  ? 138 SER B CA  1 
ATOM   5047 C C   . SER B 1 138 ? 88.114  109.461 134.350 1.00 55.92  ? 138 SER B C   1 
ATOM   5048 O O   . SER B 1 138 ? 87.631  109.719 135.456 1.00 55.92  ? 138 SER B O   1 
ATOM   5049 C CB  . SER B 1 138 ? 86.765  107.996 132.829 1.00 55.92  ? 138 SER B CB  1 
ATOM   5050 O OG  . SER B 1 138 ? 87.851  107.196 132.400 1.00 55.92  ? 138 SER B OG  1 
ATOM   5051 N N   . LEU B 1 139 ? 89.414  109.194 134.188 1.00 59.20  ? 139 LEU B N   1 
ATOM   5052 C CA  . LEU B 1 139 ? 90.327  109.301 135.322 1.00 59.20  ? 139 LEU B CA  1 
ATOM   5053 C C   . LEU B 1 139 ? 90.377  110.730 135.848 1.00 59.20  ? 139 LEU B C   1 
ATOM   5054 O O   . LEU B 1 139 ? 90.321  110.958 137.064 1.00 59.20  ? 139 LEU B O   1 
ATOM   5055 C CB  . LEU B 1 139 ? 91.724  108.819 134.929 1.00 59.20  ? 139 LEU B CB  1 
ATOM   5056 C CG  . LEU B 1 139 ? 91.918  107.310 134.764 1.00 59.20  ? 139 LEU B CG  1 
ATOM   5057 C CD1 . LEU B 1 139 ? 93.393  106.964 134.634 1.00 59.20  ? 139 LEU B CD1 1 
ATOM   5058 C CD2 . LEU B 1 139 ? 91.290  106.555 135.924 1.00 59.20  ? 139 LEU B CD2 1 
ATOM   5059 N N   . GLU B 1 140 ? 90.464  111.711 134.942 1.00 69.08  ? 140 GLU B N   1 
ATOM   5060 C CA  . GLU B 1 140 ? 90.491  113.107 135.375 1.00 69.08  ? 140 GLU B CA  1 
ATOM   5061 C C   . GLU B 1 140 ? 89.182  113.502 136.057 1.00 69.08  ? 140 GLU B C   1 
ATOM   5062 O O   . GLU B 1 140 ? 89.189  114.184 137.093 1.00 69.08  ? 140 GLU B O   1 
ATOM   5063 C CB  . GLU B 1 140 ? 90.780  114.019 134.184 1.00 69.08  ? 140 GLU B CB  1 
ATOM   5064 C CG  . GLU B 1 140 ? 90.418  115.477 134.407 1.00 69.08  ? 140 GLU B CG  1 
ATOM   5065 C CD  . GLU B 1 140 ? 91.543  116.411 134.018 1.00 69.08  ? 140 GLU B CD  1 
ATOM   5066 O OE1 . GLU B 1 140 ? 92.142  116.203 132.944 1.00 69.08  ? 140 GLU B OE1 1 
ATOM   5067 O OE2 . GLU B 1 140 ? 91.834  117.351 134.788 1.00 69.08  ? 140 GLU B OE2 1 
ATOM   5068 N N   . THR B 1 141 ? 88.049  113.073 135.495 1.00 65.82  ? 141 THR B N   1 
ATOM   5069 C CA  . THR B 1 141 ? 86.753  113.394 136.086 1.00 65.82  ? 141 THR B CA  1 
ATOM   5070 C C   . THR B 1 141 ? 86.589  112.749 137.457 1.00 65.82  ? 141 THR B C   1 
ATOM   5071 O O   . THR B 1 141 ? 86.067  113.374 138.387 1.00 65.82  ? 141 THR B O   1 
ATOM   5072 C CB  . THR B 1 141 ? 85.635  112.967 135.134 1.00 65.82  ? 141 THR B CB  1 
ATOM   5073 O OG1 . THR B 1 141 ? 85.470  113.970 134.125 1.00 65.82  ? 141 THR B OG1 1 
ATOM   5074 C CG2 . THR B 1 141 ? 84.315  112.776 135.871 1.00 65.82  ? 141 THR B CG2 1 
ATOM   5075 N N   . ILE B 1 142 ? 87.034  111.498 137.602 1.00 68.94  ? 142 ILE B N   1 
ATOM   5076 C CA  . ILE B 1 142 ? 86.963  110.813 138.888 1.00 68.94  ? 142 ILE B CA  1 
ATOM   5077 C C   . ILE B 1 142 ? 87.840  111.518 139.914 1.00 68.94  ? 142 ILE B C   1 
ATOM   5078 O O   . ILE B 1 142 ? 87.457  111.671 141.082 1.00 68.94  ? 142 ILE B O   1 
ATOM   5079 C CB  . ILE B 1 142 ? 87.352  109.331 138.713 1.00 68.94  ? 142 ILE B CB  1 
ATOM   5080 C CG1 . ILE B 1 142 ? 86.119  108.500 138.355 1.00 68.94  ? 142 ILE B CG1 1 
ATOM   5081 C CG2 . ILE B 1 142 ? 88.030  108.780 139.960 1.00 68.94  ? 142 ILE B CG2 1 
ATOM   5082 C CD1 . ILE B 1 142 ? 85.214  108.213 139.531 1.00 68.94  ? 142 ILE B CD1 1 
ATOM   5083 N N   . SER B 1 143 ? 89.027  111.968 139.494 1.00 74.08  ? 143 SER B N   1 
ATOM   5084 C CA  . SER B 1 143 ? 89.896  112.715 140.399 1.00 74.08  ? 143 SER B CA  1 
ATOM   5085 C C   . SER B 1 143 ? 89.245  114.019 140.844 1.00 74.08  ? 143 SER B C   1 
ATOM   5086 O O   . SER B 1 143 ? 89.348  114.404 142.015 1.00 74.08  ? 143 SER B O   1 
ATOM   5087 C CB  . SER B 1 143 ? 91.238  112.991 139.725 1.00 74.08  ? 143 SER B CB  1 
ATOM   5088 O OG  . SER B 1 143 ? 91.105  113.974 138.714 1.00 74.08  ? 143 SER B OG  1 
ATOM   5089 N N   . LYS B 1 144 ? 88.574  114.716 139.926 1.00 75.76  ? 144 LYS B N   1 
ATOM   5090 C CA  . LYS B 1 144 ? 87.990  116.009 140.278 1.00 75.76  ? 144 LYS B CA  1 
ATOM   5091 C C   . LYS B 1 144 ? 86.735  115.861 141.135 1.00 75.76  ? 144 LYS B C   1 
ATOM   5092 O O   . LYS B 1 144 ? 86.524  116.644 142.068 1.00 75.76  ? 144 LYS B O   1 
ATOM   5093 C CB  . LYS B 1 144 ? 87.681  116.813 139.017 1.00 75.76  ? 144 LYS B CB  1 
ATOM   5094 C CG  . LYS B 1 144 ? 88.887  117.522 138.423 1.00 75.76  ? 144 LYS B CG  1 
ATOM   5095 C CD  . LYS B 1 144 ? 88.636  117.919 136.979 1.00 75.76  ? 144 LYS B CD  1 
ATOM   5096 C CE  . LYS B 1 144 ? 89.607  119.000 136.529 1.00 75.76  ? 144 LYS B CE  1 
ATOM   5097 N NZ  . LYS B 1 144 ? 91.023  118.612 136.770 1.00 75.76  ? 144 LYS B NZ  1 
ATOM   5098 N N   . LEU B 1 145 ? 85.888  114.881 140.832 1.00 80.83  ? 145 LEU B N   1 
ATOM   5099 C CA  . LEU B 1 145 ? 84.585  114.797 141.480 1.00 80.83  ? 145 LEU B CA  1 
ATOM   5100 C C   . LEU B 1 145 ? 84.744  114.401 142.949 1.00 80.83  ? 145 LEU B C   1 
ATOM   5101 O O   . LEU B 1 145 ? 85.606  113.582 143.283 1.00 80.83  ? 145 LEU B O   1 
ATOM   5102 C CB  . LEU B 1 145 ? 83.684  113.808 140.731 1.00 80.83  ? 145 LEU B CB  1 
ATOM   5103 C CG  . LEU B 1 145 ? 83.676  112.291 140.959 1.00 80.83  ? 145 LEU B CG  1 
ATOM   5104 C CD1 . LEU B 1 145 ? 82.763  111.881 142.111 1.00 80.83  ? 145 LEU B CD1 1 
ATOM   5105 C CD2 . LEU B 1 145 ? 83.287  111.564 139.684 1.00 80.83  ? 145 LEU B CD2 1 
ATOM   5106 N N   . PRO B 1 146 ? 83.931  114.968 143.850 1.00 90.01  ? 146 PRO B N   1 
ATOM   5107 C CA  . PRO B 1 146 ? 84.110  114.737 145.290 1.00 90.01  ? 146 PRO B CA  1 
ATOM   5108 C C   . PRO B 1 146 ? 83.450  113.446 145.765 1.00 90.01  ? 146 PRO B C   1 
ATOM   5109 O O   . PRO B 1 146 ? 82.223  113.320 145.766 1.00 90.01  ? 146 PRO B O   1 
ATOM   5110 C CB  . PRO B 1 146 ? 83.459  115.975 145.920 1.00 90.01  ? 146 PRO B CB  1 
ATOM   5111 C CG  . PRO B 1 146 ? 82.386  116.353 144.949 1.00 90.01  ? 146 PRO B CG  1 
ATOM   5112 C CD  . PRO B 1 146 ? 82.903  115.991 143.577 1.00 90.01  ? 146 PRO B CD  1 
ATOM   5113 N N   . ILE B 1 147 ? 84.277  112.489 146.183 1.00 95.87  ? 147 ILE B N   1 
ATOM   5114 C CA  . ILE B 1 147 ? 83.818  111.270 146.847 1.00 95.87  ? 147 ILE B CA  1 
ATOM   5115 C C   . ILE B 1 147 ? 84.856  110.859 147.883 1.00 95.87  ? 147 ILE B C   1 
ATOM   5116 O O   . ILE B 1 147 ? 85.863  111.549 148.079 1.00 95.87  ? 147 ILE B O   1 
ATOM   5117 C CB  . ILE B 1 147 ? 83.565  110.120 145.854 1.00 95.87  ? 147 ILE B CB  1 
ATOM   5118 C CG1 . ILE B 1 147 ? 84.626  110.114 144.751 1.00 95.87  ? 147 ILE B CG1 1 
ATOM   5119 C CG2 . ILE B 1 147 ? 82.146  110.176 145.297 1.00 95.87  ? 147 ILE B CG2 1 
ATOM   5120 C CD1 . ILE B 1 147 ? 84.423  109.027 143.718 1.00 95.87  ? 147 ILE B CD1 1 
ATOM   5121 N N   . SER B 1 148 ? 84.612  109.738 148.558 1.00 102.14 ? 148 SER B N   1 
ATOM   5122 C CA  . SER B 1 148 ? 85.589  109.193 149.489 1.00 102.14 ? 148 SER B CA  1 
ATOM   5123 C C   . SER B 1 148 ? 86.835  108.722 148.746 1.00 102.14 ? 148 SER B C   1 
ATOM   5124 O O   . SER B 1 148 ? 86.766  108.256 147.604 1.00 102.14 ? 148 SER B O   1 
ATOM   5125 C CB  . SER B 1 148 ? 84.984  108.037 150.286 1.00 102.14 ? 148 SER B CB  1 
ATOM   5126 O OG  . SER B 1 148 ? 85.996  107.263 150.905 1.00 102.14 ? 148 SER B OG  1 
ATOM   5127 N N   . ASP B 1 149 ? 87.983  108.840 149.420 1.00 102.80 ? 149 ASP B N   1 
ATOM   5128 C CA  . ASP B 1 149 ? 89.265  108.548 148.783 1.00 102.80 ? 149 ASP B CA  1 
ATOM   5129 C C   . ASP B 1 149 ? 89.349  107.089 148.350 1.00 102.80 ? 149 ASP B C   1 
ATOM   5130 O O   . ASP B 1 149 ? 89.845  106.790 147.256 1.00 102.80 ? 149 ASP B O   1 
ATOM   5131 C CB  . ASP B 1 149 ? 90.406  108.908 149.742 1.00 102.80 ? 149 ASP B CB  1 
ATOM   5132 C CG  . ASP B 1 149 ? 91.785  108.842 149.090 1.00 102.80 ? 149 ASP B CG  1 
ATOM   5133 O OD1 . ASP B 1 149 ? 92.163  107.791 148.531 1.00 102.80 ? 149 ASP B OD1 1 
ATOM   5134 O OD2 . ASP B 1 149 ? 92.503  109.863 149.140 1.00 102.80 ? 149 ASP B OD2 1 
ATOM   5135 N N   . HIS B 1 150 ? 88.882  106.169 149.199 1.00 98.74  ? 150 HIS B N   1 
ATOM   5136 C CA  . HIS B 1 150 ? 88.877  104.755 148.836 1.00 98.74  ? 150 HIS B CA  1 
ATOM   5137 C C   . HIS B 1 150 ? 88.029  104.512 147.595 1.00 98.74  ? 150 HIS B C   1 
ATOM   5138 O O   . HIS B 1 150 ? 88.397  103.710 146.726 1.00 98.74  ? 150 HIS B O   1 
ATOM   5139 C CB  . HIS B 1 150 ? 88.367  103.917 150.008 1.00 98.74  ? 150 HIS B CB  1 
ATOM   5140 C CG  . HIS B 1 150 ? 88.045  102.502 149.643 1.00 98.74  ? 150 HIS B CG  1 
ATOM   5141 N ND1 . HIS B 1 150 ? 88.983  101.637 149.121 1.00 98.74  ? 150 HIS B ND1 1 
ATOM   5142 C CD2 . HIS B 1 150 ? 86.890  101.802 149.722 1.00 98.74  ? 150 HIS B CD2 1 
ATOM   5143 C CE1 . HIS B 1 150 ? 88.418  100.465 148.896 1.00 98.74  ? 150 HIS B CE1 1 
ATOM   5144 N NE2 . HIS B 1 150 ? 87.148  100.537 149.252 1.00 98.74  ? 150 HIS B NE2 1 
ATOM   5145 N N   . LEU B 1 151 ? 86.889  105.200 147.497 1.00 93.93  ? 151 LEU B N   1 
ATOM   5146 C CA  . LEU B 1 151 ? 86.072  105.119 146.293 1.00 93.93  ? 151 LEU B CA  1 
ATOM   5147 C C   . LEU B 1 151 ? 86.834  105.630 145.077 1.00 93.93  ? 151 LEU B C   1 
ATOM   5148 O O   . LEU B 1 151 ? 86.742  105.046 143.991 1.00 93.93  ? 151 LEU B O   1 
ATOM   5149 C CB  . LEU B 1 151 ? 84.774  105.904 146.484 1.00 93.93  ? 151 LEU B CB  1 
ATOM   5150 C CG  . LEU B 1 151 ? 83.672  105.229 147.302 1.00 93.93  ? 151 LEU B CG  1 
ATOM   5151 C CD1 . LEU B 1 151 ? 82.352  105.964 147.130 1.00 93.93  ? 151 LEU B CD1 1 
ATOM   5152 C CD2 . LEU B 1 151 ? 83.526  103.766 146.914 1.00 93.93  ? 151 LEU B CD2 1 
ATOM   5153 N N   . LYS B 1 152 ? 87.594  106.720 145.241 1.00 86.68  ? 152 LYS B N   1 
ATOM   5154 C CA  . LYS B 1 152 ? 88.389  107.235 144.128 1.00 86.68  ? 152 LYS B CA  1 
ATOM   5155 C C   . LYS B 1 152 ? 89.409  106.207 143.650 1.00 86.68  ? 152 LYS B C   1 
ATOM   5156 O O   . LYS B 1 152 ? 89.538  105.961 142.445 1.00 86.68  ? 152 LYS B O   1 
ATOM   5157 C CB  . LYS B 1 152 ? 89.095  108.535 144.521 1.00 86.68  ? 152 LYS B CB  1 
ATOM   5158 C CG  . LYS B 1 152 ? 88.211  109.573 145.178 1.00 86.68  ? 152 LYS B CG  1 
ATOM   5159 C CD  . LYS B 1 152 ? 89.021  110.771 145.649 1.00 86.68  ? 152 LYS B CD  1 
ATOM   5160 C CE  . LYS B 1 152 ? 89.323  111.720 144.501 1.00 86.68  ? 152 LYS B CE  1 
ATOM   5161 N NZ  . LYS B 1 152 ? 88.091  112.379 143.987 1.00 86.68  ? 152 LYS B NZ  1 
ATOM   5162 N N   . THR B 1 153 ? 90.144  105.592 144.583 1.00 85.42  ? 153 THR B N   1 
ATOM   5163 C CA  . THR B 1 153 ? 91.139  104.596 144.182 1.00 85.42  ? 153 THR B CA  1 
ATOM   5164 C C   . THR B 1 153 ? 90.491  103.385 143.522 1.00 85.42  ? 153 THR B C   1 
ATOM   5165 O O   . THR B 1 153 ? 90.988  102.894 142.501 1.00 85.42  ? 153 THR B O   1 
ATOM   5166 C CB  . THR B 1 153 ? 92.007  104.147 145.363 1.00 85.42  ? 153 THR B CB  1 
ATOM   5167 O OG1 . THR B 1 153 ? 91.387  103.042 146.038 1.00 85.42  ? 153 THR B OG1 1 
ATOM   5168 C CG2 . THR B 1 153 ? 92.309  105.279 146.322 1.00 85.42  ? 153 THR B CG2 1 
ATOM   5169 N N   . LEU B 1 154 ? 89.385  102.888 144.082 1.00 79.12  ? 154 LEU B N   1 
ATOM   5170 C CA  . LEU B 1 154 ? 88.728  101.724 143.491 1.00 79.12  ? 154 LEU B CA  1 
ATOM   5171 C C   . LEU B 1 154 ? 88.210  102.029 142.089 1.00 79.12  ? 154 LEU B C   1 
ATOM   5172 O O   . LEU B 1 154 ? 88.400  101.232 141.157 1.00 79.12  ? 154 LEU B O   1 
ATOM   5173 C CB  . LEU B 1 154 ? 87.590  101.248 144.391 1.00 79.12  ? 154 LEU B CB  1 
ATOM   5174 C CG  . LEU B 1 154 ? 86.924  99.934  143.980 1.00 79.12  ? 154 LEU B CG  1 
ATOM   5175 C CD1 . LEU B 1 154 ? 87.945  98.810  143.933 1.00 79.12  ? 154 LEU B CD1 1 
ATOM   5176 C CD2 . LEU B 1 154 ? 85.787  99.587  144.927 1.00 79.12  ? 154 LEU B CD2 1 
ATOM   5177 N N   . TYR B 1 155 ? 87.564  103.186 141.916 1.00 72.72  ? 155 TYR B N   1 
ATOM   5178 C CA  . TYR B 1 155 ? 87.030  103.558 140.612 1.00 72.72  ? 155 TYR B CA  1 
ATOM   5179 C C   . TYR B 1 155 ? 88.145  103.772 139.597 1.00 72.72  ? 155 TYR B C   1 
ATOM   5180 O O   . TYR B 1 155 ? 88.010  103.382 138.433 1.00 72.72  ? 155 TYR B O   1 
ATOM   5181 C CB  . TYR B 1 155 ? 86.168  104.814 140.743 1.00 72.72  ? 155 TYR B CB  1 
ATOM   5182 C CG  . TYR B 1 155 ? 84.856  104.597 141.472 1.00 72.72  ? 155 TYR B CG  1 
ATOM   5183 C CD1 . TYR B 1 155 ? 84.441  103.324 141.842 1.00 72.72  ? 155 TYR B CD1 1 
ATOM   5184 C CD2 . TYR B 1 155 ? 84.045  105.673 141.808 1.00 72.72  ? 155 TYR B CD2 1 
ATOM   5185 C CE1 . TYR B 1 155 ? 83.249  103.127 142.512 1.00 72.72  ? 155 TYR B CE1 1 
ATOM   5186 C CE2 . TYR B 1 155 ? 82.853  105.486 142.482 1.00 72.72  ? 155 TYR B CE2 1 
ATOM   5187 C CZ  . TYR B 1 155 ? 82.459  104.211 142.828 1.00 72.72  ? 155 TYR B CZ  1 
ATOM   5188 O OH  . TYR B 1 155 ? 81.272  104.021 143.496 1.00 72.72  ? 155 TYR B OH  1 
ATOM   5189 N N   . SER B 1 156 ? 89.253  104.388 140.015 1.00 73.45  ? 156 SER B N   1 
ATOM   5190 C CA  . SER B 1 156 ? 90.368  104.597 139.098 1.00 73.45  ? 156 SER B CA  1 
ATOM   5191 C C   . SER B 1 156 ? 91.037  103.280 138.724 1.00 73.45  ? 156 SER B C   1 
ATOM   5192 O O   . SER B 1 156 ? 91.507  103.118 137.592 1.00 73.45  ? 156 SER B O   1 
ATOM   5193 C CB  . SER B 1 156 ? 91.382  105.556 139.720 1.00 73.45  ? 156 SER B CB  1 
ATOM   5194 O OG  . SER B 1 156 ? 90.734  106.689 140.271 1.00 73.45  ? 156 SER B OG  1 
ATOM   5195 N N   . ASN B 1 157 ? 91.097  102.331 139.659 1.00 70.79  ? 157 ASN B N   1 
ATOM   5196 C CA  . ASN B 1 157 ? 91.758  101.062 139.384 1.00 70.79  ? 157 ASN B CA  1 
ATOM   5197 C C   . ASN B 1 157 ? 90.910  100.138 138.519 1.00 70.79  ? 157 ASN B C   1 
ATOM   5198 O O   . ASN B 1 157 ? 91.464  99.353  137.741 1.00 70.79  ? 157 ASN B O   1 
ATOM   5199 C CB  . ASN B 1 157 ? 92.116  100.362 140.695 1.00 70.79  ? 157 ASN B CB  1 
ATOM   5200 C CG  . ASN B 1 157 ? 93.448  100.820 141.252 1.00 70.79  ? 157 ASN B CG  1 
ATOM   5201 O OD1 . ASN B 1 157 ? 93.890  101.940 140.994 1.00 70.79  ? 157 ASN B OD1 1 
ATOM   5202 N ND2 . ASN B 1 157 ? 94.099  99.953  142.019 1.00 70.79  ? 157 ASN B ND2 1 
ATOM   5203 N N   . GLN B 1 158 ? 89.582  100.204 138.637 1.00 60.11  ? 158 GLN B N   1 
ATOM   5204 C CA  . GLN B 1 158 ? 88.747  99.245  137.919 1.00 60.11  ? 158 GLN B CA  1 
ATOM   5205 C C   . GLN B 1 158 ? 88.638  99.528  136.422 1.00 60.11  ? 158 GLN B C   1 
ATOM   5206 O O   . GLN B 1 158 ? 88.222  98.637  135.675 1.00 60.11  ? 158 GLN B O   1 
ATOM   5207 C CB  . GLN B 1 158 ? 87.346  99.199  138.534 1.00 60.11  ? 158 GLN B CB  1 
ATOM   5208 C CG  . GLN B 1 158 ? 87.278  98.459  139.862 1.00 60.11  ? 158 GLN B CG  1 
ATOM   5209 C CD  . GLN B 1 158 ? 85.862  98.073  140.240 1.00 60.11  ? 158 GLN B CD  1 
ATOM   5210 O OE1 . GLN B 1 158 ? 84.911  98.370  139.519 1.00 60.11  ? 158 GLN B OE1 1 
ATOM   5211 N NE2 . GLN B 1 158 ? 85.714  97.405  141.379 1.00 60.11  ? 158 GLN B NE2 1 
ATOM   5212 N N   . ILE B 1 159 ? 88.988  100.735 135.966 1.00 51.41  ? 159 ILE B N   1 
ATOM   5213 C CA  . ILE B 1 159 ? 88.725  101.106 134.570 1.00 51.41  ? 159 ILE B CA  1 
ATOM   5214 C C   . ILE B 1 159 ? 89.533  100.296 133.558 1.00 51.41  ? 159 ILE B C   1 
ATOM   5215 O O   . ILE B 1 159 ? 88.926  99.735  132.631 1.00 51.41  ? 159 ILE B O   1 
ATOM   5216 C CB  . ILE B 1 159 ? 88.890  102.622 134.382 1.00 51.41  ? 159 ILE B CB  1 
ATOM   5217 C CG1 . ILE B 1 159 ? 87.899  103.379 135.266 1.00 51.41  ? 159 ILE B CG1 1 
ATOM   5218 C CG2 . ILE B 1 159 ? 88.717  102.996 132.920 1.00 51.41  ? 159 ILE B CG2 1 
ATOM   5219 C CD1 . ILE B 1 159 ? 87.769  104.849 134.930 1.00 51.41  ? 159 ILE B CD1 1 
ATOM   5220 N N   . PRO B 1 160 ? 90.872  100.209 133.642 1.00 44.37  ? 160 PRO B N   1 
ATOM   5221 C CA  . PRO B 1 160 ? 91.607  99.503  132.574 1.00 44.37  ? 160 PRO B CA  1 
ATOM   5222 C C   . PRO B 1 160 ? 91.240  98.037  132.435 1.00 44.37  ? 160 PRO B C   1 
ATOM   5223 O O   . PRO B 1 160 ? 91.265  97.504  131.316 1.00 44.37  ? 160 PRO B O   1 
ATOM   5224 C CB  . PRO B 1 160 ? 93.075  99.673  132.985 1.00 44.37  ? 160 PRO B CB  1 
ATOM   5225 C CG  . PRO B 1 160 ? 93.092  100.861 133.850 1.00 44.37  ? 160 PRO B CG  1 
ATOM   5226 C CD  . PRO B 1 160 ? 91.812  100.793 134.618 1.00 44.37  ? 160 PRO B CD  1 
ATOM   5227 N N   . ILE B 1 161 ? 90.897  97.370  133.539 1.00 42.54  ? 161 ILE B N   1 
ATOM   5228 C CA  . ILE B 1 161 ? 90.562  95.951  133.486 1.00 42.54  ? 161 ILE B CA  1 
ATOM   5229 C C   . ILE B 1 161 ? 89.317  95.724  132.638 1.00 42.54  ? 161 ILE B C   1 
ATOM   5230 O O   . ILE B 1 161 ? 89.304  94.872  131.741 1.00 42.54  ? 161 ILE B O   1 
ATOM   5231 C CB  . ILE B 1 161 ? 90.372  95.393  134.905 1.00 42.54  ? 161 ILE B CB  1 
ATOM   5232 C CG1 . ILE B 1 161 ? 91.717  95.305  135.630 1.00 42.54  ? 161 ILE B CG1 1 
ATOM   5233 C CG2 . ILE B 1 161 ? 89.688  94.045  134.840 1.00 42.54  ? 161 ILE B CG2 1 
ATOM   5234 C CD1 . ILE B 1 161 ? 91.754  94.265  136.727 1.00 42.54  ? 161 ILE B CD1 1 
ATOM   5235 N N   . VAL B 1 162 ? 88.257  96.490  132.906 1.00 41.25  ? 162 VAL B N   1 
ATOM   5236 C CA  . VAL B 1 162 ? 87.033  96.355  132.125 1.00 41.25  ? 162 VAL B CA  1 
ATOM   5237 C C   . VAL B 1 162 ? 87.279  96.778  130.683 1.00 41.25  ? 162 VAL B C   1 
ATOM   5238 O O   . VAL B 1 162 ? 86.688  96.218  129.751 1.00 41.25  ? 162 VAL B O   1 
ATOM   5239 C CB  . VAL B 1 162 ? 85.901  97.164  132.786 1.00 41.25  ? 162 VAL B CB  1 
ATOM   5240 C CG1 . VAL B 1 162 ? 84.660  97.184  131.912 1.00 41.25  ? 162 VAL B CG1 1 
ATOM   5241 C CG2 . VAL B 1 162 ? 85.577  96.593  134.158 1.00 41.25  ? 162 VAL B CG2 1 
ATOM   5242 N N   . TYR B 1 163 ? 88.174  97.747  130.476 1.00 38.51  ? 163 TYR B N   1 
ATOM   5243 C CA  . TYR B 1 163 ? 88.531  98.177  129.127 1.00 38.51  ? 163 TYR B CA  1 
ATOM   5244 C C   . TYR B 1 163 ? 89.126  97.036  128.312 1.00 38.51  ? 163 TYR B C   1 
ATOM   5245 O O   . TYR B 1 163 ? 88.689  96.775  127.182 1.00 38.51  ? 163 TYR B O   1 
ATOM   5246 C CB  . TYR B 1 163 ? 89.522  99.338  129.215 1.00 38.51  ? 163 TYR B CB  1 
ATOM   5247 C CG  . TYR B 1 163 ? 90.111  99.779  127.897 1.00 38.51  ? 163 TYR B CG  1 
ATOM   5248 C CD1 . TYR B 1 163 ? 89.311  100.311 126.900 1.00 38.51  ? 163 TYR B CD1 1 
ATOM   5249 C CD2 . TYR B 1 163 ? 91.473  99.655  127.652 1.00 38.51  ? 163 TYR B CD2 1 
ATOM   5250 C CE1 . TYR B 1 163 ? 89.852  100.720 125.698 1.00 38.51  ? 163 TYR B CE1 1 
ATOM   5251 C CE2 . TYR B 1 163 ? 92.020  100.058 126.455 1.00 38.51  ? 163 TYR B CE2 1 
ATOM   5252 C CZ  . TYR B 1 163 ? 91.206  100.589 125.481 1.00 38.51  ? 163 TYR B CZ  1 
ATOM   5253 O OH  . TYR B 1 163 ? 91.754  100.990 124.287 1.00 38.51  ? 163 TYR B OH  1 
ATOM   5254 N N   . THR B 1 164 ? 90.119  96.336  128.873 1.00 37.90  ? 164 THR B N   1 
ATOM   5255 C CA  . THR B 1 164 ? 90.784  95.264  128.134 1.00 37.90  ? 164 THR B CA  1 
ATOM   5256 C C   . THR B 1 164 ? 89.862  94.076  127.899 1.00 37.90  ? 164 THR B C   1 
ATOM   5257 O O   . THR B 1 164 ? 90.011  93.370  126.895 1.00 37.90  ? 164 THR B O   1 
ATOM   5258 C CB  . THR B 1 164 ? 92.043  94.803  128.871 1.00 37.90  ? 164 THR B CB  1 
ATOM   5259 O OG1 . THR B 1 164 ? 91.677  94.239  130.137 1.00 37.90  ? 164 THR B OG1 1 
ATOM   5260 C CG2 . THR B 1 164 ? 93.006  95.960  129.080 1.00 37.90  ? 164 THR B CG2 1 
ATOM   5261 N N   . LEU B 1 165 ? 88.923  93.830  128.812 1.00 42.49  ? 165 LEU B N   1 
ATOM   5262 C CA  . LEU B 1 165 ? 87.979  92.732  128.628 1.00 42.49  ? 165 LEU B CA  1 
ATOM   5263 C C   . LEU B 1 165 ? 87.082  92.966  127.422 1.00 42.49  ? 165 LEU B C   1 
ATOM   5264 O O   . LEU B 1 165 ? 86.917  92.082  126.574 1.00 42.49  ? 165 LEU B O   1 
ATOM   5265 C CB  . LEU B 1 165 ? 87.132  92.550  129.886 1.00 42.49  ? 165 LEU B CB  1 
ATOM   5266 C CG  . LEU B 1 165 ? 87.854  92.027  131.120 1.00 42.49  ? 165 LEU B CG  1 
ATOM   5267 C CD1 . LEU B 1 165 ? 86.854  91.603  132.170 1.00 42.49  ? 165 LEU B CD1 1 
ATOM   5268 C CD2 . LEU B 1 165 ? 88.727  90.864  130.726 1.00 42.49  ? 165 LEU B CD2 1 
ATOM   5269 N N   . THR B 1 166 ? 86.489  94.153  127.333 1.00 40.32  ? 166 THR B N   1 
ATOM   5270 C CA  . THR B 1 166 ? 85.455  94.388  126.338 1.00 40.32  ? 166 THR B CA  1 
ATOM   5271 C C   . THR B 1 166 ? 86.038  94.818  124.992 1.00 40.32  ? 166 THR B C   1 
ATOM   5272 O O   . THR B 1 166 ? 85.425  94.548  123.951 1.00 40.32  ? 166 THR B O   1 
ATOM   5273 C CB  . THR B 1 166 ? 84.457  95.408  126.908 1.00 40.32  ? 166 THR B CB  1 
ATOM   5274 O OG1 . THR B 1 166 ? 83.546  94.726  127.778 1.00 40.32  ? 166 THR B OG1 1 
ATOM   5275 C CG2 . THR B 1 166 ? 83.622  96.040  125.827 1.00 40.32  ? 166 THR B CG2 1 
ATOM   5276 N N   . TYR B 1 167 ? 87.240  95.414  124.978 1.00 36.20  ? 167 TYR B N   1 
ATOM   5277 C CA  . TYR B 1 167 ? 87.886  95.772  123.715 1.00 36.20  ? 167 TYR B CA  1 
ATOM   5278 C C   . TYR B 1 167 ? 88.080  94.563  122.808 1.00 36.20  ? 167 TYR B C   1 
ATOM   5279 O O   . TYR B 1 167 ? 88.019  94.697  121.581 1.00 36.20  ? 167 TYR B O   1 
ATOM   5280 C CB  . TYR B 1 167 ? 89.228  96.458  124.000 1.00 36.20  ? 167 TYR B CB  1 
ATOM   5281 C CG  . TYR B 1 167 ? 89.815  97.277  122.861 1.00 36.20  ? 167 TYR B CG  1 
ATOM   5282 C CD1 . TYR B 1 167 ? 90.297  96.671  121.709 1.00 36.20  ? 167 TYR B CD1 1 
ATOM   5283 C CD2 . TYR B 1 167 ? 89.884  98.661  122.942 1.00 36.20  ? 167 TYR B CD2 1 
ATOM   5284 C CE1 . TYR B 1 167 ? 90.833  97.412  120.676 1.00 36.20  ? 167 TYR B CE1 1 
ATOM   5285 C CE2 . TYR B 1 167 ? 90.418  99.413  121.911 1.00 36.20  ? 167 TYR B CE2 1 
ATOM   5286 C CZ  . TYR B 1 167 ? 90.890  98.783  120.783 1.00 36.20  ? 167 TYR B CZ  1 
ATOM   5287 O OH  . TYR B 1 167 ? 91.423  99.525  119.753 1.00 36.20  ? 167 TYR B OH  1 
ATOM   5288 N N   . VAL B 1 168 ? 88.300  93.380  123.387 1.00 39.54  ? 168 VAL B N   1 
ATOM   5289 C CA  . VAL B 1 168 ? 88.546  92.186  122.581 1.00 39.54  ? 168 VAL B CA  1 
ATOM   5290 C C   . VAL B 1 168 ? 87.339  91.879  121.702 1.00 39.54  ? 168 VAL B C   1 
ATOM   5291 O O   . VAL B 1 168 ? 87.473  91.609  120.502 1.00 39.54  ? 168 VAL B O   1 
ATOM   5292 C CB  . VAL B 1 168 ? 88.900  90.992  123.485 1.00 39.54  ? 168 VAL B CB  1 
ATOM   5293 C CG1 . VAL B 1 168 ? 88.813  89.683  122.711 1.00 39.54  ? 168 VAL B CG1 1 
ATOM   5294 C CG2 . VAL B 1 168 ? 90.280  91.174  124.092 1.00 39.54  ? 168 VAL B CG2 1 
ATOM   5295 N N   . PHE B 1 169 ? 86.138  91.931  122.280 1.00 45.26  ? 169 PHE B N   1 
ATOM   5296 C CA  . PHE B 1 169 ? 84.952  91.607  121.496 1.00 45.26  ? 169 PHE B CA  1 
ATOM   5297 C C   . PHE B 1 169 ? 84.567  92.728  120.541 1.00 45.26  ? 169 PHE B C   1 
ATOM   5298 O O   . PHE B 1 169 ? 84.032  92.453  119.463 1.00 45.26  ? 169 PHE B O   1 
ATOM   5299 C CB  . PHE B 1 169 ? 83.766  91.289  122.398 1.00 45.26  ? 169 PHE B CB  1 
ATOM   5300 C CG  . PHE B 1 169 ? 82.524  90.922  121.638 1.00 45.26  ? 169 PHE B CG  1 
ATOM   5301 C CD1 . PHE B 1 169 ? 82.429  89.705  120.985 1.00 45.26  ? 169 PHE B CD1 1 
ATOM   5302 C CD2 . PHE B 1 169 ? 81.473  91.816  121.535 1.00 45.26  ? 169 PHE B CD2 1 
ATOM   5303 C CE1 . PHE B 1 169 ? 81.290  89.374  120.270 1.00 45.26  ? 169 PHE B CE1 1 
ATOM   5304 C CE2 . PHE B 1 169 ? 80.338  91.493  120.821 1.00 45.26  ? 169 PHE B CE2 1 
ATOM   5305 C CZ  . PHE B 1 169 ? 80.244  90.271  120.189 1.00 45.26  ? 169 PHE B CZ  1 
ATOM   5306 N N   . GLY B 1 170 ? 84.809  93.984  120.921 1.00 42.74  ? 170 GLY B N   1 
ATOM   5307 C CA  . GLY B 1 170 ? 84.297  95.093  120.132 1.00 42.74  ? 170 GLY B CA  1 
ATOM   5308 C C   . GLY B 1 170 ? 84.841  95.115  118.717 1.00 42.74  ? 170 GLY B C   1 
ATOM   5309 O O   . GLY B 1 170 ? 84.078  95.116  117.749 1.00 42.74  ? 170 GLY B O   1 
ATOM   5310 N N   . THR B 1 171 ? 86.168  95.058  118.579 1.00 38.23  ? 171 THR B N   1 
ATOM   5311 C CA  . THR B 1 171 ? 86.771  95.199  117.259 1.00 38.23  ? 171 THR B CA  1 
ATOM   5312 C C   . THR B 1 171 ? 86.396  94.037  116.351 1.00 38.23  ? 171 THR B C   1 
ATOM   5313 O O   . THR B 1 171 ? 85.881  94.249  115.249 1.00 38.23  ? 171 THR B O   1 
ATOM   5314 C CB  . THR B 1 171 ? 88.290  95.306  117.387 1.00 38.23  ? 171 THR B CB  1 
ATOM   5315 O OG1 . THR B 1 171 ? 88.636  96.587  117.926 1.00 38.23  ? 171 THR B OG1 1 
ATOM   5316 C CG2 . THR B 1 171 ? 88.953  95.137  116.030 1.00 38.23  ? 171 THR B CG2 1 
ATOM   5317 N N   . ILE B 1 172 ? 86.589  92.804  116.822 1.00 41.54  ? 172 ILE B N   1 
ATOM   5318 C CA  . ILE B 1 172 ? 86.327  91.636  115.988 1.00 41.54  ? 172 ILE B CA  1 
ATOM   5319 C C   . ILE B 1 172 ? 84.841  91.538  115.659 1.00 41.54  ? 172 ILE B C   1 
ATOM   5320 O O   . ILE B 1 172 ? 84.456  91.343  114.498 1.00 41.54  ? 172 ILE B O   1 
ATOM   5321 C CB  . ILE B 1 172 ? 86.838  90.361  116.684 1.00 41.54  ? 172 ILE B CB  1 
ATOM   5322 C CG1 . ILE B 1 172 ? 88.335  90.180  116.434 1.00 41.54  ? 172 ILE B CG1 1 
ATOM   5323 C CG2 . ILE B 1 172 ? 86.061  89.137  116.218 1.00 41.54  ? 172 ILE B CG2 1 
ATOM   5324 C CD1 . ILE B 1 172 ? 88.866  88.828  116.864 1.00 41.54  ? 172 ILE B CD1 1 
ATOM   5325 N N   . GLY B 1 173 ? 83.986  91.702  116.671 1.00 44.43  ? 173 GLY B N   1 
ATOM   5326 C CA  . GLY B 1 173 ? 82.558  91.554  116.449 1.00 44.43  ? 173 GLY B CA  1 
ATOM   5327 C C   . GLY B 1 173 ? 81.991  92.597  115.508 1.00 44.43  ? 173 GLY B C   1 
ATOM   5328 O O   . GLY B 1 173 ? 81.260  92.266  114.568 1.00 44.43  ? 173 GLY B O   1 
ATOM   5329 N N   . VAL B 1 174 ? 82.324  93.872  115.731 1.00 41.39  ? 174 VAL B N   1 
ATOM   5330 C CA  . VAL B 1 174 ? 81.760  94.907  114.875 1.00 41.39  ? 174 VAL B CA  1 
ATOM   5331 C C   . VAL B 1 174 ? 82.389  94.854  113.487 1.00 41.39  ? 174 VAL B C   1 
ATOM   5332 O O   . VAL B 1 174 ? 81.726  95.154  112.487 1.00 41.39  ? 174 VAL B O   1 
ATOM   5333 C CB  . VAL B 1 174 ? 81.899  96.292  115.527 1.00 41.39  ? 174 VAL B CB  1 
ATOM   5334 C CG1 . VAL B 1 174 ? 81.226  97.343  114.672 1.00 41.39  ? 174 VAL B CG1 1 
ATOM   5335 C CG2 . VAL B 1 174 ? 81.259  96.282  116.892 1.00 41.39  ? 174 VAL B CG2 1 
ATOM   5336 N N   . LEU B 1 175 ? 83.662  94.453  113.391 1.00 41.34  ? 175 LEU B N   1 
ATOM   5337 C CA  . LEU B 1 175 ? 84.275  94.266  112.082 1.00 41.34  ? 175 LEU B CA  1 
ATOM   5338 C C   . LEU B 1 175 ? 83.534  93.205  111.277 1.00 41.34  ? 175 LEU B C   1 
ATOM   5339 O O   . LEU B 1 175 ? 83.185  93.425  110.110 1.00 41.34  ? 175 LEU B O   1 
ATOM   5340 C CB  . LEU B 1 175 ? 85.744  93.882  112.250 1.00 41.34  ? 175 LEU B CB  1 
ATOM   5341 C CG  . LEU B 1 175 ? 86.550  93.683  110.965 1.00 41.34  ? 175 LEU B CG  1 
ATOM   5342 C CD1 . LEU B 1 175 ? 87.192  94.984  110.514 1.00 41.34  ? 175 LEU B CD1 1 
ATOM   5343 C CD2 . LEU B 1 175 ? 87.596  92.598  111.159 1.00 41.34  ? 175 LEU B CD2 1 
ATOM   5344 N N   . ILE B 1 176 ? 83.258  92.057  111.900 1.00 42.37  ? 176 ILE B N   1 
ATOM   5345 C CA  . ILE B 1 176 ? 82.527  90.995  111.213 1.00 42.37  ? 176 ILE B CA  1 
ATOM   5346 C C   . ILE B 1 176 ? 81.126  91.469  110.839 1.00 42.37  ? 176 ILE B C   1 
ATOM   5347 O O   . ILE B 1 176 ? 80.663  91.261  109.709 1.00 42.37  ? 176 ILE B O   1 
ATOM   5348 C CB  . ILE B 1 176 ? 82.493  89.726  112.088 1.00 42.37  ? 176 ILE B CB  1 
ATOM   5349 C CG1 . ILE B 1 176 ? 83.703  88.843  111.785 1.00 42.37  ? 176 ILE B CG1 1 
ATOM   5350 C CG2 . ILE B 1 176 ? 81.211  88.935  111.869 1.00 42.37  ? 176 ILE B CG2 1 
ATOM   5351 C CD1 . ILE B 1 176 ? 83.801  87.615  112.663 1.00 42.37  ? 176 ILE B CD1 1 
ATOM   5352 N N   . PHE B 1 177 ? 80.452  92.154  111.770 1.00 42.95  ? 177 PHE B N   1 
ATOM   5353 C CA  . PHE B 1 177 ? 79.074  92.578  111.540 1.00 42.95  ? 177 PHE B CA  1 
ATOM   5354 C C   . PHE B 1 177 ? 78.977  93.604  110.416 1.00 42.95  ? 177 PHE B C   1 
ATOM   5355 O O   . PHE B 1 177 ? 78.037  93.566  109.614 1.00 42.95  ? 177 PHE B O   1 
ATOM   5356 C CB  . PHE B 1 177 ? 78.484  93.140  112.831 1.00 42.95  ? 177 PHE B CB  1 
ATOM   5357 C CG  . PHE B 1 177 ? 77.041  93.528  112.715 1.00 42.95  ? 177 PHE B CG  1 
ATOM   5358 C CD1 . PHE B 1 177 ? 76.096  92.602  112.315 1.00 42.95  ? 177 PHE B CD1 1 
ATOM   5359 C CD2 . PHE B 1 177 ? 76.628  94.813  113.016 1.00 42.95  ? 177 PHE B CD2 1 
ATOM   5360 C CE1 . PHE B 1 177 ? 74.767  92.949  112.209 1.00 42.95  ? 177 PHE B CE1 1 
ATOM   5361 C CE2 . PHE B 1 177 ? 75.299  95.166  112.915 1.00 42.95  ? 177 PHE B CE2 1 
ATOM   5362 C CZ  . PHE B 1 177 ? 74.368  94.234  112.507 1.00 42.95  ? 177 PHE B CZ  1 
ATOM   5363 N N   . LEU B 1 178 ? 79.929  94.533  110.344 1.00 41.83  ? 178 LEU B N   1 
ATOM   5364 C CA  . LEU B 1 178 ? 79.900  95.572  109.326 1.00 41.83  ? 178 LEU B CA  1 
ATOM   5365 C C   . LEU B 1 178 ? 80.561  95.158  108.021 1.00 41.83  ? 178 LEU B C   1 
ATOM   5366 O O   . LEU B 1 178 ? 80.448  95.892  107.034 1.00 41.83  ? 178 LEU B O   1 
ATOM   5367 C CB  . LEU B 1 178 ? 80.578  96.848  109.834 1.00 41.83  ? 178 LEU B CB  1 
ATOM   5368 C CG  . LEU B 1 178 ? 79.885  97.617  110.953 1.00 41.83  ? 178 LEU B CG  1 
ATOM   5369 C CD1 . LEU B 1 178 ? 80.714  98.826  111.363 1.00 41.83  ? 178 LEU B CD1 1 
ATOM   5370 C CD2 . LEU B 1 178 ? 78.497  98.030  110.520 1.00 41.83  ? 178 LEU B CD2 1 
ATOM   5371 N N   . ARG B 1 179 ? 81.254  94.022  107.982 1.00 51.47  ? 179 ARG B N   1 
ATOM   5372 C CA  . ARG B 1 179 ? 81.883  93.600  106.739 1.00 51.47  ? 179 ARG B CA  1 
ATOM   5373 C C   . ARG B 1 179 ? 81.150  92.466  106.035 1.00 51.47  ? 179 ARG B C   1 
ATOM   5374 O O   . ARG B 1 179 ? 81.161  92.412  104.803 1.00 51.47  ? 179 ARG B O   1 
ATOM   5375 C CB  . ARG B 1 179 ? 83.332  93.185  106.994 1.00 51.47  ? 179 ARG B CB  1 
ATOM   5376 C CG  . ARG B 1 179 ? 84.260  93.509  105.841 1.00 51.47  ? 179 ARG B CG  1 
ATOM   5377 C CD  . ARG B 1 179 ? 85.606  92.848  106.027 1.00 51.47  ? 179 ARG B CD  1 
ATOM   5378 N NE  . ARG B 1 179 ? 85.480  91.427  106.325 1.00 51.47  ? 179 ARG B NE  1 
ATOM   5379 C CZ  . ARG B 1 179 ? 86.222  90.785  107.216 1.00 51.47  ? 179 ARG B CZ  1 
ATOM   5380 N NH1 . ARG B 1 179 ? 87.153  91.410  107.918 1.00 51.47  ? 179 ARG B NH1 1 
ATOM   5381 N NH2 . ARG B 1 179 ? 86.025  89.483  107.408 1.00 51.47  ? 179 ARG B NH2 1 
ATOM   5382 N N   . ASP B 1 180 ? 80.525  91.547  106.771 1.00 53.94  ? 180 ASP B N   1 
ATOM   5383 C CA  . ASP B 1 180 ? 79.868  90.408  106.138 1.00 53.94  ? 180 ASP B CA  1 
ATOM   5384 C C   . ASP B 1 180 ? 78.363  90.388  106.353 1.00 53.94  ? 180 ASP B C   1 
ATOM   5385 O O   . ASP B 1 180 ? 77.604  90.240  105.383 1.00 53.94  ? 180 ASP B O   1 
ATOM   5386 C CB  . ASP B 1 180 ? 80.477  89.092  106.650 1.00 53.94  ? 180 ASP B CB  1 
ATOM   5387 C CG  . ASP B 1 180 ? 81.937  88.929  106.265 1.00 53.94  ? 180 ASP B CG  1 
ATOM   5388 O OD1 . ASP B 1 180 ? 82.494  89.832  105.608 1.00 53.94  ? 180 ASP B OD1 1 
ATOM   5389 O OD2 . ASP B 1 180 ? 82.529  87.889  106.621 1.00 53.94  ? 180 ASP B OD2 1 
ATOM   5390 N N   . ILE B 1 181 ? 77.910  90.533  107.600 1.00 51.01  ? 181 ILE B N   1 
ATOM   5391 C CA  . ILE B 1 181 ? 76.503  90.306  107.920 1.00 51.01  ? 181 ILE B CA  1 
ATOM   5392 C C   . ILE B 1 181 ? 75.618  91.354  107.255 1.00 51.01  ? 181 ILE B C   1 
ATOM   5393 O O   . ILE B 1 181 ? 74.597  91.023  106.646 1.00 51.01  ? 181 ILE B O   1 
ATOM   5394 C CB  . ILE B 1 181 ? 76.300  90.277  109.445 1.00 51.01  ? 181 ILE B CB  1 
ATOM   5395 C CG1 . ILE B 1 181 ? 77.002  89.059  110.053 1.00 51.01  ? 181 ILE B CG1 1 
ATOM   5396 C CG2 . ILE B 1 181 ? 74.822  90.267  109.791 1.00 51.01  ? 181 ILE B CG2 1 
ATOM   5397 C CD1 . ILE B 1 181 ? 76.410  87.731  109.626 1.00 51.01  ? 181 ILE B CD1 1 
ATOM   5398 N N   . MET B 1 182 ? 75.986  92.629  107.372 1.00 54.66  ? 182 MET B N   1 
ATOM   5399 C CA  . MET B 1 182 ? 75.190  93.683  106.743 1.00 54.66  ? 182 MET B CA  1 
ATOM   5400 C C   . MET B 1 182 ? 75.167  93.595  105.218 1.00 54.66  ? 182 MET B C   1 
ATOM   5401 O O   . MET B 1 182 ? 74.084  93.783  104.634 1.00 54.66  ? 182 MET B O   1 
ATOM   5402 C CB  . MET B 1 182 ? 75.667  95.057  107.227 1.00 54.66  ? 182 MET B CB  1 
ATOM   5403 C CG  . MET B 1 182 ? 74.628  96.156  107.051 1.00 54.66  ? 182 MET B CG  1 
ATOM   5404 S SD  . MET B 1 182 ? 74.796  97.523  108.211 1.00 54.66  ? 182 MET B SD  1 
ATOM   5405 C CE  . MET B 1 182 ? 74.831  96.634  109.760 1.00 54.66  ? 182 MET B CE  1 
ATOM   5406 N N   . PRO B 1 183 ? 76.284  93.363  104.510 1.00 57.54  ? 183 PRO B N   1 
ATOM   5407 C CA  . PRO B 1 183 ? 76.165  93.107  103.063 1.00 57.54  ? 183 PRO B CA  1 
ATOM   5408 C C   . PRO B 1 183 ? 75.326  91.886  102.720 1.00 57.54  ? 183 PRO B C   1 
ATOM   5409 O O   . PRO B 1 183 ? 74.599  91.919  101.719 1.00 57.54  ? 183 PRO B O   1 
ATOM   5410 C CB  . PRO B 1 183 ? 77.622  92.947  102.607 1.00 57.54  ? 183 PRO B CB  1 
ATOM   5411 C CG  . PRO B 1 183 ? 78.419  93.640  103.631 1.00 57.54  ? 183 PRO B CG  1 
ATOM   5412 C CD  . PRO B 1 183 ? 77.700  93.456  104.918 1.00 57.54  ? 183 PRO B CD  1 
ATOM   5413 N N   . LYS B 1 184 ? 75.386  90.814  103.518 1.00 57.34  ? 184 LYS B N   1 
ATOM   5414 C CA  . LYS B 1 184 ? 74.511  89.674  103.251 1.00 57.34  ? 184 LYS B CA  1 
ATOM   5415 C C   . LYS B 1 184 ? 73.046  90.048  103.430 1.00 57.34  ? 184 LYS B C   1 
ATOM   5416 O O   . LYS B 1 184 ? 72.188  89.610  102.655 1.00 57.34  ? 184 LYS B O   1 
ATOM   5417 C CB  . LYS B 1 184 ? 74.877  88.490  104.146 1.00 57.34  ? 184 LYS B CB  1 
ATOM   5418 C CG  . LYS B 1 184 ? 76.006  87.632  103.600 1.00 57.34  ? 184 LYS B CG  1 
ATOM   5419 C CD  . LYS B 1 184 ? 76.812  86.988  104.713 1.00 57.34  ? 184 LYS B CD  1 
ATOM   5420 C CE  . LYS B 1 184 ? 78.071  86.338  104.167 1.00 57.34  ? 184 LYS B CE  1 
ATOM   5421 N NZ  . LYS B 1 184 ? 78.852  85.644  105.228 1.00 57.34  ? 184 LYS B NZ  1 
ATOM   5422 N N   . LEU B 1 185 ? 72.738  90.854  104.449 1.00 59.19  ? 185 LEU B N   1 
ATOM   5423 C CA  . LEU B 1 185 ? 71.358  91.274  104.670 1.00 59.19  ? 185 LEU B CA  1 
ATOM   5424 C C   . LEU B 1 185 ? 70.861  92.187  103.556 1.00 59.19  ? 185 LEU B C   1 
ATOM   5425 O O   . LEU B 1 185 ? 69.703  92.082  103.135 1.00 59.19  ? 185 LEU B O   1 
ATOM   5426 C CB  . LEU B 1 185 ? 71.219  91.959  106.030 1.00 59.19  ? 185 LEU B CB  1 
ATOM   5427 C CG  . LEU B 1 185 ? 71.481  91.106  107.274 1.00 59.19  ? 185 LEU B CG  1 
ATOM   5428 C CD1 . LEU B 1 185 ? 70.840  91.734  108.499 1.00 59.19  ? 185 LEU B CD1 1 
ATOM   5429 C CD2 . LEU B 1 185 ? 70.979  89.682  107.078 1.00 59.19  ? 185 LEU B CD2 1 
ATOM   5430 N N   . MET B 1 186 ? 71.707  93.091  103.065 1.00 67.50  ? 186 MET B N   1 
ATOM   5431 C CA  . MET B 1 186 ? 71.273  93.982  101.995 1.00 67.50  ? 186 MET B CA  1 
ATOM   5432 C C   . MET B 1 186 ? 71.358  93.351  100.611 1.00 67.50  ? 186 MET B C   1 
ATOM   5433 O O   . MET B 1 186 ? 70.857  93.951  99.653  1.00 67.50  ? 186 MET B O   1 
ATOM   5434 C CB  . MET B 1 186 ? 72.077  95.286  101.998 1.00 67.50  ? 186 MET B CB  1 
ATOM   5435 C CG  . MET B 1 186 ? 71.361  96.443  102.678 1.00 67.50  ? 186 MET B CG  1 
ATOM   5436 S SD  . MET B 1 186 ? 72.364  97.936  102.788 1.00 67.50  ? 186 MET B SD  1 
ATOM   5437 C CE  . MET B 1 186 ? 73.718  97.371  103.805 1.00 67.50  ? 186 MET B CE  1 
ATOM   5438 N N   . HIS B 1 187 ? 71.962  92.164  100.490 1.00 71.37  ? 187 HIS B N   1 
ATOM   5439 C CA  . HIS B 1 187 ? 72.052  91.433  99.223  1.00 71.37  ? 187 HIS B CA  1 
ATOM   5440 C C   . HIS B 1 187 ? 72.797  92.244  98.161  1.00 71.37  ? 187 HIS B C   1 
ATOM   5441 O O   . HIS B 1 187 ? 72.402  92.297  96.996  1.00 71.37  ? 187 HIS B O   1 
ATOM   5442 C CB  . HIS B 1 187 ? 70.663  91.020  98.723  1.00 71.37  ? 187 HIS B CB  1 
ATOM   5443 C CG  . HIS B 1 187 ? 70.087  89.837  99.436  1.00 71.37  ? 187 HIS B CG  1 
ATOM   5444 N ND1 . HIS B 1 187 ? 70.869  88.906  100.086 1.00 71.37  ? 187 HIS B ND1 1 
ATOM   5445 C CD2 . HIS B 1 187 ? 68.805  89.436  99.606  1.00 71.37  ? 187 HIS B CD2 1 
ATOM   5446 C CE1 . HIS B 1 187 ? 70.092  87.980  100.621 1.00 71.37  ? 187 HIS B CE1 1 
ATOM   5447 N NE2 . HIS B 1 187 ? 68.837  88.279  100.346 1.00 71.37  ? 187 HIS B NE2 1 
ATOM   5448 N N   . ILE B 1 188 ? 73.895  92.877  98.579  1.00 76.97  ? 188 ILE B N   1 
ATOM   5449 C CA  . ILE B 1 188 ? 74.740  93.669  97.695  1.00 76.97  ? 188 ILE B CA  1 
ATOM   5450 C C   . ILE B 1 188 ? 76.174  93.173  97.810  1.00 76.97  ? 188 ILE B C   1 
ATOM   5451 O O   . ILE B 1 188 ? 76.550  92.494  98.768  1.00 76.97  ? 188 ILE B O   1 
ATOM   5452 C CB  . ILE B 1 188 ? 74.682  95.186  98.005  1.00 76.97  ? 188 ILE B CB  1 
ATOM   5453 C CG1 . ILE B 1 188 ? 75.717  95.562  99.070  1.00 76.97  ? 188 ILE B CG1 1 
ATOM   5454 C CG2 . ILE B 1 188 ? 73.286  95.616  98.421  1.00 76.97  ? 188 ILE B CG2 1 
ATOM   5455 C CD1 . ILE B 1 188 ? 75.853  97.047  99.296  1.00 76.97  ? 188 ILE B CD1 1 
ATOM   5456 N N   . ASP B 1 189 ? 76.972  93.503  96.800  1.00 82.34  ? 189 ASP B N   1 
ATOM   5457 C CA  . ASP B 1 189 ? 78.410  93.295  96.848  1.00 82.34  ? 189 ASP B CA  1 
ATOM   5458 C C   . ASP B 1 189 ? 79.115  94.618  97.110  1.00 82.34  ? 189 ASP B C   1 
ATOM   5459 O O   . ASP B 1 189 ? 78.803  95.640  96.485  1.00 82.34  ? 189 ASP B O   1 
ATOM   5460 C CB  . ASP B 1 189 ? 78.925  92.663  95.555  1.00 82.34  ? 189 ASP B CB  1 
ATOM   5461 C CG  . ASP B 1 189 ? 79.119  91.164  95.682  1.00 82.34  ? 189 ASP B CG  1 
ATOM   5462 O OD1 . ASP B 1 189 ? 78.800  90.613  96.758  1.00 82.34  ? 189 ASP B OD1 1 
ATOM   5463 O OD2 . ASP B 1 189 ? 79.592  90.536  94.712  1.00 82.34  ? 189 ASP B OD2 1 
ATOM   5464 N N   . LEU B 1 190 ? 80.071  94.582  98.043  1.00 75.39  ? 190 LEU B N   1 
ATOM   5465 C CA  . LEU B 1 190 ? 80.739  95.796  98.501  1.00 75.39  ? 190 LEU B CA  1 
ATOM   5466 C C   . LEU B 1 190 ? 81.491  96.488  97.375  1.00 75.39  ? 190 LEU B C   1 
ATOM   5467 O O   . LEU B 1 190 ? 81.496  97.722  97.300  1.00 75.39  ? 190 LEU B O   1 
ATOM   5468 C CB  . LEU B 1 190 ? 81.701  95.456  99.638  1.00 75.39  ? 190 LEU B CB  1 
ATOM   5469 C CG  . LEU B 1 190 ? 81.810  96.455  100.787 1.00 75.39  ? 190 LEU B CG  1 
ATOM   5470 C CD1 . LEU B 1 190 ? 80.503  96.530  101.554 1.00 75.39  ? 190 LEU B CD1 1 
ATOM   5471 C CD2 . LEU B 1 190 ? 82.950  96.057  101.706 1.00 75.39  ? 190 LEU B CD2 1 
ATOM   5472 N N   . LYS B 1 191 ? 82.133  95.717  96.500  1.00 79.35  ? 191 LYS B N   1 
ATOM   5473 C CA  . LYS B 1 191 ? 82.838  96.308  95.369  1.00 79.35  ? 191 LYS B CA  1 
ATOM   5474 C C   . LYS B 1 191 ? 81.858  96.923  94.374  1.00 79.35  ? 191 LYS B C   1 
ATOM   5475 O O   . LYS B 1 191 ? 81.977  98.101  94.013  1.00 79.35  ? 191 LYS B O   1 
ATOM   5476 C CB  . LYS B 1 191 ? 83.693  95.235  94.692  1.00 79.35  ? 191 LYS B CB  1 
ATOM   5477 C CG  . LYS B 1 191 ? 84.136  95.560  93.280  1.00 79.35  ? 191 LYS B CG  1 
ATOM   5478 C CD  . LYS B 1 191 ? 85.478  96.269  93.271  1.00 79.35  ? 191 LYS B CD  1 
ATOM   5479 C CE  . LYS B 1 191 ? 86.540  95.414  93.947  1.00 79.35  ? 191 LYS B CE  1 
ATOM   5480 N NZ  . LYS B 1 191 ? 87.866  96.085  93.978  1.00 79.35  ? 191 LYS B NZ  1 
ATOM   5481 N N   . LYS B 1 192 ? 80.847  96.151  93.970  1.00 82.96  ? 192 LYS B N   1 
ATOM   5482 C CA  . LYS B 1 192 ? 79.993  96.530  92.848  1.00 82.96  ? 192 LYS B CA  1 
ATOM   5483 C C   . LYS B 1 192 ? 79.087  97.705  93.191  1.00 82.96  ? 192 LYS B C   1 
ATOM   5484 O O   . LYS B 1 192 ? 78.973  98.653  92.405  1.00 82.96  ? 192 LYS B O   1 
ATOM   5485 C CB  . LYS B 1 192 ? 79.156  95.332  92.395  1.00 82.96  ? 192 LYS B CB  1 
ATOM   5486 C CG  . LYS B 1 192 ? 79.966  94.141  91.918  1.00 82.96  ? 192 LYS B CG  1 
ATOM   5487 C CD  . LYS B 1 192 ? 79.329  93.510  90.690  1.00 82.96  ? 192 LYS B CD  1 
ATOM   5488 C CE  . LYS B 1 192 ? 80.201  92.407  90.117  1.00 82.96  ? 192 LYS B CE  1 
ATOM   5489 N NZ  . LYS B 1 192 ? 81.428  92.186  90.929  1.00 82.96  ? 192 LYS B NZ  1 
ATOM   5490 N N   . GLN B 1 193 ? 78.426  97.659  94.351  1.00 85.47  ? 193 GLN B N   1 
ATOM   5491 C CA  . GLN B 1 193 ? 77.503  98.736  94.702  1.00 85.47  ? 193 GLN B CA  1 
ATOM   5492 C C   . GLN B 1 193 ? 78.239  100.054 94.904  1.00 85.47  ? 193 GLN B C   1 
ATOM   5493 O O   . GLN B 1 193 ? 77.755  101.113 94.484  1.00 85.47  ? 193 GLN B O   1 
ATOM   5494 C CB  . GLN B 1 193 ? 76.703  98.365  95.952  1.00 85.47  ? 193 GLN B CB  1 
ATOM   5495 C CG  . GLN B 1 193 ? 75.445  99.204  96.169  1.00 85.47  ? 193 GLN B CG  1 
ATOM   5496 C CD  . GLN B 1 193 ? 74.299  98.840  95.232  1.00 85.47  ? 193 GLN B CD  1 
ATOM   5497 O OE1 . GLN B 1 193 ? 74.476  98.108  94.257  1.00 85.47  ? 193 GLN B OE1 1 
ATOM   5498 N NE2 . GLN B 1 193 ? 73.113  99.356  95.528  1.00 85.47  ? 193 GLN B NE2 1 
ATOM   5499 N N   . ALA B 1 194 ? 79.410  100.008 95.541  1.00 86.57  ? 194 ALA B N   1 
ATOM   5500 C CA  . ALA B 1 194 ? 80.188  101.225 95.739  1.00 86.57  ? 194 ALA B CA  1 
ATOM   5501 C C   . ALA B 1 194 ? 80.698  101.781 94.419  1.00 86.57  ? 194 ALA B C   1 
ATOM   5502 O O   . ALA B 1 194 ? 80.710  103.001 94.219  1.00 86.57  ? 194 ALA B O   1 
ATOM   5503 C CB  . ALA B 1 194 ? 81.346  100.964 96.696  1.00 86.57  ? 194 ALA B CB  1 
ATOM   5504 N N   . VAL B 1 195 ? 81.128  100.906 93.503  1.00 89.02  ? 195 VAL B N   1 
ATOM   5505 C CA  . VAL B 1 195 ? 81.563  101.377 92.190  1.00 89.02  ? 195 VAL B CA  1 
ATOM   5506 C C   . VAL B 1 195 ? 80.406  102.030 91.443  1.00 89.02  ? 195 VAL B C   1 
ATOM   5507 O O   . VAL B 1 195 ? 80.567  103.085 90.820  1.00 89.02  ? 195 VAL B O   1 
ATOM   5508 C CB  . VAL B 1 195 ? 82.184  100.221 91.384  1.00 89.02  ? 195 VAL B CB  1 
ATOM   5509 C CG1 . VAL B 1 195 ? 82.234  100.561 89.902  1.00 89.02  ? 195 VAL B CG1 1 
ATOM   5510 C CG2 . VAL B 1 195 ? 83.579  99.918  91.902  1.00 89.02  ? 195 VAL B CG2 1 
ATOM   5511 N N   . LYS B 1 196 ? 79.220  101.417 91.503  1.00 91.66  ? 196 LYS B N   1 
ATOM   5512 C CA  . LYS B 1 196 ? 78.057  101.993 90.834  1.00 91.66  ? 196 LYS B CA  1 
ATOM   5513 C C   . LYS B 1 196 ? 77.690  103.352 91.421  1.00 91.66  ? 196 LYS B C   1 
ATOM   5514 O O   . LYS B 1 196 ? 77.397  104.300 90.680  1.00 91.66  ? 196 LYS B O   1 
ATOM   5515 C CB  . LYS B 1 196 ? 76.874  101.031 90.923  1.00 91.66  ? 196 LYS B CB  1 
ATOM   5516 C CG  . LYS B 1 196 ? 75.545  101.642 90.518  1.00 91.66  ? 196 LYS B CG  1 
ATOM   5517 C CD  . LYS B 1 196 ? 74.383  100.936 91.196  1.00 91.66  ? 196 LYS B CD  1 
ATOM   5518 C CE  . LYS B 1 196 ? 74.434  99.435  90.961  1.00 91.66  ? 196 LYS B CE  1 
ATOM   5519 N NZ  . LYS B 1 196 ? 73.572  98.700  91.927  1.00 91.66  ? 196 LYS B NZ  1 
ATOM   5520 N N   . THR B 1 197 ? 77.703  103.471 92.751  1.00 93.03  ? 197 THR B N   1 
ATOM   5521 C CA  . THR B 1 197 ? 77.370  104.749 93.371  1.00 93.03  ? 197 THR B CA  1 
ATOM   5522 C C   . THR B 1 197 ? 78.415  105.814 93.045  1.00 93.03  ? 197 THR B C   1 
ATOM   5523 O O   . THR B 1 197 ? 78.068  106.976 92.798  1.00 93.03  ? 197 THR B O   1 
ATOM   5524 C CB  . THR B 1 197 ? 77.220  104.583 94.881  1.00 93.03  ? 197 THR B CB  1 
ATOM   5525 O OG1 . THR B 1 197 ? 76.417  103.427 95.154  1.00 93.03  ? 197 THR B OG1 1 
ATOM   5526 C CG2 . THR B 1 197 ? 76.529  105.800 95.473  1.00 93.03  ? 197 THR B CG2 1 
ATOM   5527 N N   . ALA B 1 198 ? 79.697  105.435 93.033  1.00 97.11  ? 198 ALA B N   1 
ATOM   5528 C CA  . ALA B 1 198 ? 80.747  106.380 92.667  1.00 97.11  ? 198 ALA B CA  1 
ATOM   5529 C C   . ALA B 1 198 ? 80.635  106.805 91.209  1.00 97.11  ? 198 ALA B C   1 
ATOM   5530 O O   . ALA B 1 198 ? 80.974  107.944 90.871  1.00 97.11  ? 198 ALA B O   1 
ATOM   5531 C CB  . ALA B 1 198 ? 82.122  105.771 92.941  1.00 97.11  ? 198 ALA B CB  1 
ATOM   5532 N N   . LYS B 1 199 ? 80.183  105.904 90.334  1.00 100.44 ? 199 LYS B N   1 
ATOM   5533 C CA  . LYS B 1 199 ? 79.925  106.282 88.948  1.00 100.44 ? 199 LYS B CA  1 
ATOM   5534 C C   . LYS B 1 199 ? 78.744  107.238 88.847  1.00 100.44 ? 199 LYS B C   1 
ATOM   5535 O O   . LYS B 1 199 ? 78.749  108.152 88.014  1.00 100.44 ? 199 LYS B O   1 
ATOM   5536 C CB  . LYS B 1 199 ? 79.676  105.036 88.099  1.00 100.44 ? 199 LYS B CB  1 
ATOM   5537 C CG  . LYS B 1 199 ? 80.938  104.361 87.607  1.00 100.44 ? 199 LYS B CG  1 
ATOM   5538 C CD  . LYS B 1 199 ? 81.577  105.169 86.493  1.00 100.44 ? 199 LYS B CD  1 
ATOM   5539 C CE  . LYS B 1 199 ? 82.832  104.492 85.979  1.00 100.44 ? 199 LYS B CE  1 
ATOM   5540 N NZ  . LYS B 1 199 ? 83.935  104.553 86.974  1.00 100.44 ? 199 LYS B NZ  1 
ATOM   5541 N N   . GLU B 1 200 ? 77.713  107.025 89.671  1.00 103.33 ? 200 GLU B N   1 
ATOM   5542 C CA  . GLU B 1 200 ? 76.583  107.952 89.695  1.00 103.33 ? 200 GLU B CA  1 
ATOM   5543 C C   . GLU B 1 200 ? 77.041  109.336 90.135  1.00 103.33 ? 200 GLU B C   1 
ATOM   5544 O O   . GLU B 1 200 ? 76.663  110.346 89.529  1.00 103.33 ? 200 GLU B O   1 
ATOM   5545 C CB  . GLU B 1 200 ? 75.479  107.396 90.608  1.00 103.33 ? 200 GLU B CB  1 
ATOM   5546 C CG  . GLU B 1 200 ? 74.034  107.943 90.436  1.00 103.33 ? 200 GLU B CG  1 
ATOM   5547 C CD  . GLU B 1 200 ? 73.863  109.458 90.517  1.00 103.33 ? 200 GLU B CD  1 
ATOM   5548 O OE1 . GLU B 1 200 ? 74.551  110.120 91.322  1.00 103.33 ? 200 GLU B OE1 1 
ATOM   5549 O OE2 . GLU B 1 200 ? 73.032  109.994 89.754  1.00 103.33 ? 200 GLU B OE2 1 
ATOM   5550 N N   . LEU B 1 201 ? 77.880  109.402 91.164  1.00 100.51 ? 201 LEU B N   1 
ATOM   5551 C CA  . LEU B 1 201 ? 78.474  110.663 91.581  1.00 100.51 ? 201 LEU B CA  1 
ATOM   5552 C C   . LEU B 1 201 ? 79.746  110.908 90.770  1.00 100.51 ? 201 LEU B C   1 
ATOM   5553 O O   . LEU B 1 201 ? 79.991  110.260 89.750  1.00 100.51 ? 201 LEU B O   1 
ATOM   5554 C CB  . LEU B 1 201 ? 78.729  110.665 93.087  1.00 100.51 ? 201 LEU B CB  1 
ATOM   5555 C CG  . LEU B 1 201 ? 77.467  110.699 93.954  1.00 100.51 ? 201 LEU B CG  1 
ATOM   5556 C CD1 . LEU B 1 201 ? 77.374  109.463 94.836  1.00 100.51 ? 201 LEU B CD1 1 
ATOM   5557 C CD2 . LEU B 1 201 ? 77.406  111.967 94.790  1.00 100.51 ? 201 LEU B CD2 1 
ATOM   5558 N N   . ASP B 1 202 ? 80.559  111.874 91.193  1.00 101.65 ? 202 ASP B N   1 
ATOM   5559 C CA  . ASP B 1 202 ? 81.820  112.165 90.521  1.00 101.65 ? 202 ASP B CA  1 
ATOM   5560 C C   . ASP B 1 202 ? 83.006  112.034 91.472  1.00 101.65 ? 202 ASP B C   1 
ATOM   5561 O O   . ASP B 1 202 ? 84.023  112.710 91.304  1.00 101.65 ? 202 ASP B O   1 
ATOM   5562 C CB  . ASP B 1 202 ? 81.793  113.554 89.883  1.00 101.65 ? 202 ASP B CB  1 
ATOM   5563 C CG  . ASP B 1 202 ? 81.133  114.586 90.766  1.00 101.65 ? 202 ASP B CG  1 
ATOM   5564 O OD1 . ASP B 1 202 ? 79.886  114.629 90.809  1.00 101.65 ? 202 ASP B OD1 1 
ATOM   5565 O OD2 . ASP B 1 202 ? 81.868  115.364 91.409  1.00 101.65 ? 202 ASP B OD2 1 
ATOM   5566 N N   . MET B 1 203 ? 82.888  111.170 92.484  1.00 99.13  ? 203 MET B N   1 
ATOM   5567 C CA  . MET B 1 203 ? 84.021  110.873 93.352  1.00 99.13  ? 203 MET B CA  1 
ATOM   5568 C C   . MET B 1 203 ? 85.087  110.029 92.668  1.00 99.13  ? 203 MET B C   1 
ATOM   5569 O O   . MET B 1 203 ? 86.174  109.866 93.233  1.00 99.13  ? 203 MET B O   1 
ATOM   5570 C CB  . MET B 1 203 ? 83.564  110.146 94.620  1.00 99.13  ? 203 MET B CB  1 
ATOM   5571 C CG  . MET B 1 203 ? 82.256  110.619 95.223  1.00 99.13  ? 203 MET B CG  1 
ATOM   5572 S SD  . MET B 1 203 ? 82.415  112.193 96.082  1.00 99.13  ? 203 MET B SD  1 
ATOM   5573 C CE  . MET B 1 203 ? 80.693  112.609 96.325  1.00 99.13  ? 203 MET B CE  1 
ATOM   5574 N N   . ILE B 1 204 ? 84.799  109.480 91.492  1.00 111.99 ? 204 ILE B N   1 
ATOM   5575 C CA  . ILE B 1 204 ? 85.754  108.589 90.823  1.00 111.99 ? 204 ILE B CA  1 
ATOM   5576 C C   . ILE B 1 204 ? 86.999  109.379 90.432  1.00 111.99 ? 204 ILE B C   1 
ATOM   5577 O O   . ILE B 1 204 ? 86.887  110.439 89.783  1.00 111.99 ? 204 ILE B O   1 
ATOM   5578 C CB  . ILE B 1 204 ? 85.101  107.925 89.595  1.00 111.99 ? 204 ILE B CB  1 
ATOM   5579 C CG1 . ILE B 1 204 ? 86.139  107.157 88.771  1.00 111.99 ? 204 ILE B CG1 1 
ATOM   5580 C CG2 . ILE B 1 204 ? 84.334  108.943 88.751  1.00 111.99 ? 204 ILE B CG2 1 
ATOM   5581 C CD1 . ILE B 1 204 ? 86.490  105.804 89.347  1.00 111.99 ? 204 ILE B CD1 1 
ATOM   5582 N N   . PRO B 1 205 ? 88.195  108.945 90.825  1.00 119.74 ? 205 PRO B N   1 
ATOM   5583 C CA  . PRO B 1 205 ? 89.406  109.685 90.456  1.00 119.74 ? 205 PRO B CA  1 
ATOM   5584 C C   . PRO B 1 205 ? 89.668  109.632 88.959  1.00 119.74 ? 205 PRO B C   1 
ATOM   5585 O O   . PRO B 1 205 ? 89.346  108.654 88.278  1.00 119.74 ? 205 PRO B O   1 
ATOM   5586 C CB  . PRO B 1 205 ? 90.513  108.969 91.238  1.00 119.74 ? 205 PRO B CB  1 
ATOM   5587 C CG  . PRO B 1 205 ? 89.968  107.606 91.503  1.00 119.74 ? 205 PRO B CG  1 
ATOM   5588 C CD  . PRO B 1 205 ? 88.493  107.791 91.688  1.00 119.74 ? 205 PRO B CD  1 
ATOM   5589 N N   . VAL B 1 206 ? 90.266  110.704 88.452  1.00 138.43 ? 206 VAL B N   1 
ATOM   5590 C CA  . VAL B 1 206 ? 90.611  110.839 87.045  1.00 138.43 ? 206 VAL B CA  1 
ATOM   5591 C C   . VAL B 1 206 ? 92.126  110.962 86.945  1.00 138.43 ? 206 VAL B C   1 
ATOM   5592 O O   . VAL B 1 206 ? 92.710  111.877 87.533  1.00 138.43 ? 206 VAL B O   1 
ATOM   5593 C CB  . VAL B 1 206 ? 89.924  112.051 86.392  1.00 138.43 ? 206 VAL B CB  1 
ATOM   5594 C CG1 . VAL B 1 206 ? 90.270  112.122 84.913  1.00 138.43 ? 206 VAL B CG1 1 
ATOM   5595 C CG2 . VAL B 1 206 ? 88.419  111.978 86.591  1.00 138.43 ? 206 VAL B CG2 1 
ATOM   5596 N N   . PRO B 1 207 ? 92.808  110.066 86.233  1.00 147.85 ? 207 PRO B N   1 
ATOM   5597 C CA  . PRO B 1 207 ? 94.261  110.189 86.090  1.00 147.85 ? 207 PRO B CA  1 
ATOM   5598 C C   . PRO B 1 207 ? 94.643  111.432 85.303  1.00 147.85 ? 207 PRO B C   1 
ATOM   5599 O O   . PRO B 1 207 ? 93.909  111.896 84.428  1.00 147.85 ? 207 PRO B O   1 
ATOM   5600 C CB  . PRO B 1 207 ? 94.654  108.913 85.337  1.00 147.85 ? 207 PRO B CB  1 
ATOM   5601 C CG  . PRO B 1 207 ? 93.411  108.507 84.619  1.00 147.85 ? 207 PRO B CG  1 
ATOM   5602 C CD  . PRO B 1 207 ? 92.279  108.889 85.524  1.00 147.85 ? 207 PRO B CD  1 
ATOM   5603 N N   . VAL B 1 208 ? 95.813  111.973 85.631  1.00 149.56 ? 208 VAL B N   1 
ATOM   5604 C CA  . VAL B 1 208 ? 96.327  113.187 85.010  1.00 149.56 ? 208 VAL B CA  1 
ATOM   5605 C C   . VAL B 1 208 ? 97.632  112.852 84.303  1.00 149.56 ? 208 VAL B C   1 
ATOM   5606 O O   . VAL B 1 208 ? 98.500  112.177 84.869  1.00 149.56 ? 208 VAL B O   1 
ATOM   5607 C CB  . VAL B 1 208 ? 96.527  114.315 86.039  1.00 149.56 ? 208 VAL B CB  1 
ATOM   5608 C CG1 . VAL B 1 208 ? 95.189  114.937 86.405  1.00 149.56 ? 208 VAL B CG1 1 
ATOM   5609 C CG2 . VAL B 1 208 ? 97.222  113.788 87.287  1.00 149.56 ? 208 VAL B CG2 1 
ATOM   5610 N N   . ILE B 1 209 ? 97.759  113.307 83.060  1.00 138.27 ? 209 ILE B N   1 
ATOM   5611 C CA  . ILE B 1 209 ? 98.964  113.112 82.263  1.00 138.27 ? 209 ILE B CA  1 
ATOM   5612 C C   . ILE B 1 209 ? 99.849  114.341 82.418  1.00 138.27 ? 209 ILE B C   1 
ATOM   5613 O O   . ILE B 1 209 ? 99.378  115.478 82.296  1.00 138.27 ? 209 ILE B O   1 
ATOM   5614 C CB  . ILE B 1 209 ? 98.623  112.839 80.786  1.00 138.27 ? 209 ILE B CB  1 
ATOM   5615 C CG1 . ILE B 1 209 ? 99.897  112.759 79.942  1.00 138.27 ? 209 ILE B CG1 1 
ATOM   5616 C CG2 . ILE B 1 209 ? 97.635  113.869 80.242  1.00 138.27 ? 209 ILE B CG2 1 
ATOM   5617 C CD1 . ILE B 1 209 ? 99.651  112.359 78.506  1.00 138.27 ? 209 ILE B CD1 1 
ATOM   5618 N N   . VAL B 1 210 ? 101.127 114.116 82.714  1.00 130.62 ? 210 VAL B N   1 
ATOM   5619 C CA  . VAL B 1 210 ? 102.091 115.185 82.936  1.00 130.62 ? 210 VAL B CA  1 
ATOM   5620 C C   . VAL B 1 210 ? 103.014 115.264 81.728  1.00 130.62 ? 210 VAL B C   1 
ATOM   5621 O O   . VAL B 1 210 ? 103.524 114.240 81.257  1.00 130.62 ? 210 VAL B O   1 
ATOM   5622 C CB  . VAL B 1 210 ? 102.880 114.973 84.243  1.00 130.62 ? 210 VAL B CB  1 
ATOM   5623 C CG1 . VAL B 1 210 ? 103.462 113.565 84.314  1.00 130.62 ? 210 VAL B CG1 1 
ATOM   5624 C CG2 . VAL B 1 210 ? 103.974 116.021 84.388  1.00 130.62 ? 210 VAL B CG2 1 
ATOM   5625 N N   . ALA B 1 211 ? 103.197 116.473 81.208  1.00 118.17 ? 211 ALA B N   1 
ATOM   5626 C CA  . ALA B 1 211 ? 104.099 116.672 80.085  1.00 118.17 ? 211 ALA B CA  1 
ATOM   5627 C C   . ALA B 1 211 ? 105.543 116.452 80.517  1.00 118.17 ? 211 ALA B C   1 
ATOM   5628 O O   . ALA B 1 211 ? 105.908 116.651 81.679  1.00 118.17 ? 211 ALA B O   1 
ATOM   5629 C CB  . ALA B 1 211 ? 103.932 118.076 79.504  1.00 118.17 ? 211 ALA B CB  1 
ATOM   5630 N N   . SER B 1 212 ? 106.368 116.031 79.563  1.00 116.03 ? 212 SER B N   1 
ATOM   5631 C CA  . SER B 1 212 ? 107.771 115.767 79.832  1.00 116.03 ? 212 SER B CA  1 
ATOM   5632 C C   . SER B 1 212 ? 108.591 116.206 78.629  1.00 116.03 ? 212 SER B C   1 
ATOM   5633 O O   . SER B 1 212 ? 108.060 116.428 77.539  1.00 116.03 ? 212 SER B O   1 
ATOM   5634 C CB  . SER B 1 212 ? 108.022 114.287 80.142  1.00 116.03 ? 212 SER B CB  1 
ATOM   5635 O OG  . SER B 1 212 ? 109.399 113.973 80.037  1.00 116.03 ? 212 SER B OG  1 
ATOM   5636 N N   . THR B 1 213 ? 109.895 116.335 78.844  1.00 118.44 ? 213 THR B N   1 
ATOM   5637 C CA  . THR B 1 213 ? 110.824 116.758 77.805  1.00 118.44 ? 213 THR B CA  1 
ATOM   5638 C C   . THR B 1 213 ? 111.474 115.517 77.206  1.00 118.44 ? 213 THR B C   1 
ATOM   5639 O O   . THR B 1 213 ? 112.238 114.820 77.882  1.00 118.44 ? 213 THR B O   1 
ATOM   5640 C CB  . THR B 1 213 ? 111.877 117.706 78.372  1.00 118.44 ? 213 THR B CB  1 
ATOM   5641 O OG1 . THR B 1 213 ? 112.218 117.300 79.703  1.00 118.44 ? 213 THR B OG1 1 
ATOM   5642 C CG2 . THR B 1 213 ? 111.343 119.127 78.405  1.00 118.44 ? 213 THR B CG2 1 
ATOM   5643 N N   . HIS B 1 214 ? 111.166 115.238 75.943  1.00 118.70 ? 214 HIS B N   1 
ATOM   5644 C CA  . HIS B 1 214 ? 111.740 114.111 75.222  1.00 118.70 ? 214 HIS B CA  1 
ATOM   5645 C C   . HIS B 1 214 ? 112.740 114.632 74.201  1.00 118.70 ? 214 HIS B C   1 
ATOM   5646 O O   . HIS B 1 214 ? 112.413 115.513 73.397  1.00 118.70 ? 214 HIS B O   1 
ATOM   5647 C CB  . HIS B 1 214 ? 110.652 113.286 74.534  1.00 118.70 ? 214 HIS B CB  1 
ATOM   5648 C CG  . HIS B 1 214 ? 109.739 112.573 75.481  1.00 118.70 ? 214 HIS B CG  1 
ATOM   5649 N ND1 . HIS B 1 214 ? 108.691 111.787 75.054  1.00 118.70 ? 214 HIS B ND1 1 
ATOM   5650 C CD2 . HIS B 1 214 ? 109.720 112.523 76.834  1.00 118.70 ? 214 HIS B CD2 1 
ATOM   5651 C CE1 . HIS B 1 214 ? 108.064 111.285 76.102  1.00 118.70 ? 214 HIS B CE1 1 
ATOM   5652 N NE2 . HIS B 1 214 ? 108.668 111.716 77.194  1.00 118.70 ? 214 HIS B NE2 1 
ATOM   5653 N N   . PHE B 1 215 ? 113.953 114.086 74.233  1.00 125.77 ? 215 PHE B N   1 
ATOM   5654 C CA  . PHE B 1 215 ? 115.064 114.592 73.429  1.00 125.77 ? 215 PHE B CA  1 
ATOM   5655 C C   . PHE B 1 215 ? 115.096 113.851 72.099  1.00 125.77 ? 215 PHE B C   1 
ATOM   5656 O O   . PHE B 1 215 ? 115.794 112.848 71.936  1.00 125.77 ? 215 PHE B O   1 
ATOM   5657 C CB  . PHE B 1 215 ? 116.378 114.438 74.183  1.00 125.77 ? 215 PHE B CB  1 
ATOM   5658 C CG  . PHE B 1 215 ? 116.325 114.938 75.597  1.00 125.77 ? 215 PHE B CG  1 
ATOM   5659 C CD1 . PHE B 1 215 ? 116.385 116.293 75.871  1.00 125.77 ? 215 PHE B CD1 1 
ATOM   5660 C CD2 . PHE B 1 215 ? 116.211 114.049 76.652  1.00 125.77 ? 215 PHE B CD2 1 
ATOM   5661 C CE1 . PHE B 1 215 ? 116.335 116.753 77.172  1.00 125.77 ? 215 PHE B CE1 1 
ATOM   5662 C CE2 . PHE B 1 215 ? 116.160 114.502 77.954  1.00 125.77 ? 215 PHE B CE2 1 
ATOM   5663 C CZ  . PHE B 1 215 ? 116.222 115.854 78.215  1.00 125.77 ? 215 PHE B CZ  1 
ATOM   5664 N N   . TYR B 1 216 ? 114.331 114.348 71.132  1.00 137.55 ? 216 TYR B N   1 
ATOM   5665 C CA  . TYR B 1 216 ? 114.400 113.820 69.778  1.00 137.55 ? 216 TYR B CA  1 
ATOM   5666 C C   . TYR B 1 216 ? 115.518 114.505 69.003  1.00 137.55 ? 216 TYR B C   1 
ATOM   5667 O O   . TYR B 1 216 ? 115.561 115.737 68.917  1.00 137.55 ? 216 TYR B O   1 
ATOM   5668 C CB  . TYR B 1 216 ? 113.074 114.009 69.042  1.00 137.55 ? 216 TYR B CB  1 
ATOM   5669 C CG  . TYR B 1 216 ? 111.922 113.181 69.560  1.00 137.55 ? 216 TYR B CG  1 
ATOM   5670 C CD1 . TYR B 1 216 ? 111.229 113.548 70.703  1.00 137.55 ? 216 TYR B CD1 1 
ATOM   5671 C CD2 . TYR B 1 216 ? 111.532 112.021 68.902  1.00 137.55 ? 216 TYR B CD2 1 
ATOM   5672 C CE1 . TYR B 1 216 ? 110.174 112.791 71.169  1.00 137.55 ? 216 TYR B CE1 1 
ATOM   5673 C CE2 . TYR B 1 216 ? 110.482 111.255 69.366  1.00 137.55 ? 216 TYR B CE2 1 
ATOM   5674 C CZ  . TYR B 1 216 ? 109.807 111.645 70.499  1.00 137.55 ? 216 TYR B CZ  1 
ATOM   5675 O OH  . TYR B 1 216 ? 108.758 110.887 70.967  1.00 137.55 ? 216 TYR B OH  1 
ATOM   5676 N N   . THR B 1 217 ? 116.407 113.706 68.427  1.00 149.88 ? 217 THR B N   1 
ATOM   5677 C CA  . THR B 1 217 ? 117.486 114.204 67.590  1.00 149.88 ? 217 THR B CA  1 
ATOM   5678 C C   . THR B 1 217 ? 117.116 114.075 66.114  1.00 149.88 ? 217 THR B C   1 
ATOM   5679 O O   . THR B 1 217 ? 116.201 113.336 65.735  1.00 149.88 ? 217 THR B O   1 
ATOM   5680 C CB  . THR B 1 217 ? 118.799 113.470 67.888  1.00 149.88 ? 217 THR B CB  1 
ATOM   5681 O OG1 . THR B 1 217 ? 119.906 114.320 67.565  1.00 149.88 ? 217 THR B OG1 1 
ATOM   5682 C CG2 . THR B 1 217 ? 118.912 112.190 67.085  1.00 149.88 ? 217 THR B CG2 1 
ATOM   5683 N N   . ILE B 1 218 ? 117.851 114.810 65.284  1.00 159.29 ? 218 ILE B N   1 
ATOM   5684 C CA  . ILE B 1 218 ? 117.473 115.090 63.903  1.00 159.29 ? 218 ILE B CA  1 
ATOM   5685 C C   . ILE B 1 218 ? 117.981 113.993 62.978  1.00 159.29 ? 218 ILE B C   1 
ATOM   5686 O O   . ILE B 1 218 ? 119.110 113.509 63.118  1.00 159.29 ? 218 ILE B O   1 
ATOM   5687 C CB  . ILE B 1 218 ? 118.005 116.476 63.482  1.00 159.29 ? 218 ILE B CB  1 
ATOM   5688 C CG1 . ILE B 1 218 ? 117.041 117.568 63.940  1.00 159.29 ? 218 ILE B CG1 1 
ATOM   5689 C CG2 . ILE B 1 218 ? 118.255 116.562 61.979  1.00 159.29 ? 218 ILE B CG2 1 
ATOM   5690 C CD1 . ILE B 1 218 ? 115.810 117.686 63.084  1.00 159.29 ? 218 ILE B CD1 1 
ATOM   5691 N N   . ASN B 1 219 ? 117.133 113.589 62.032  1.00 169.47 ? 219 ASN B N   1 
ATOM   5692 C CA  . ASN B 1 219 ? 117.563 112.757 60.916  1.00 169.47 ? 219 ASN B CA  1 
ATOM   5693 C C   . ASN B 1 219 ? 118.217 113.653 59.871  1.00 169.47 ? 219 ASN B C   1 
ATOM   5694 O O   . ASN B 1 219 ? 117.607 114.625 59.412  1.00 169.47 ? 219 ASN B O   1 
ATOM   5695 C CB  . ASN B 1 219 ? 116.372 112.003 60.325  1.00 169.47 ? 219 ASN B CB  1 
ATOM   5696 C CG  . ASN B 1 219 ? 116.622 111.519 58.906  1.00 169.47 ? 219 ASN B CG  1 
ATOM   5697 O OD1 . ASN B 1 219 ? 117.710 111.047 58.573  1.00 169.47 ? 219 ASN B OD1 1 
ATOM   5698 N ND2 . ASN B 1 219 ? 115.607 111.642 58.058  1.00 169.47 ? 219 ASN B ND2 1 
ATOM   5699 N N   . ASP B 1 220 ? 119.455 113.334 59.504  1.00 175.09 ? 220 ASP B N   1 
ATOM   5700 C CA  . ASP B 1 220 ? 120.189 114.154 58.549  1.00 175.09 ? 220 ASP B CA  1 
ATOM   5701 C C   . ASP B 1 220 ? 119.546 114.069 57.170  1.00 175.09 ? 220 ASP B C   1 
ATOM   5702 O O   . ASP B 1 220 ? 119.130 112.995 56.723  1.00 175.09 ? 220 ASP B O   1 
ATOM   5703 C CB  . ASP B 1 220 ? 121.653 113.707 58.488  1.00 175.09 ? 220 ASP B CB  1 
ATOM   5704 C CG  . ASP B 1 220 ? 122.516 114.626 57.637  1.00 175.09 ? 220 ASP B CG  1 
ATOM   5705 O OD1 . ASP B 1 220 ? 122.359 114.633 56.398  1.00 175.09 ? 220 ASP B OD1 1 
ATOM   5706 O OD2 . ASP B 1 220 ? 123.359 115.345 58.215  1.00 175.09 ? 220 ASP B OD2 1 
ATOM   5707 N N   . GLY B 1 221 ? 119.473 115.210 56.493  1.00 175.36 ? 221 GLY B N   1 
ATOM   5708 C CA  . GLY B 1 221 ? 118.862 115.273 55.176  1.00 175.36 ? 221 GLY B CA  1 
ATOM   5709 C C   . GLY B 1 221 ? 117.373 115.006 55.162  1.00 175.36 ? 221 GLY B C   1 
ATOM   5710 O O   . GLY B 1 221 ? 116.884 114.289 54.278  1.00 175.36 ? 221 GLY B O   1 
ATOM   5711 N N   . SER B 1 222 ? 116.635 115.567 56.117  1.00 174.98 ? 222 SER B N   1 
ATOM   5712 C CA  . SER B 1 222 ? 115.194 115.379 56.215  1.00 174.98 ? 222 SER B CA  1 
ATOM   5713 C C   . SER B 1 222 ? 114.401 116.454 55.485  1.00 174.98 ? 222 SER B C   1 
ATOM   5714 O O   . SER B 1 222 ? 113.171 116.480 55.610  1.00 174.98 ? 222 SER B O   1 
ATOM   5715 C CB  . SER B 1 222 ? 114.769 115.336 57.686  1.00 174.98 ? 222 SER B CB  1 
ATOM   5716 O OG  . SER B 1 222 ? 115.028 116.575 58.325  1.00 174.98 ? 222 SER B OG  1 
ATOM   5717 N N   . SER B 1 223 ? 115.082 117.365 54.779  1.00 177.82 ? 223 SER B N   1 
ATOM   5718 C CA  . SER B 1 223 ? 114.498 118.422 53.951  1.00 177.82 ? 223 SER B CA  1 
ATOM   5719 C C   . SER B 1 223 ? 113.840 119.518 54.786  1.00 177.82 ? 223 SER B C   1 
ATOM   5720 O O   . SER B 1 223 ? 113.386 120.528 54.239  1.00 177.82 ? 223 SER B O   1 
ATOM   5721 C CB  . SER B 1 223 ? 113.496 117.850 52.941  1.00 177.82 ? 223 SER B CB  1 
ATOM   5722 O OG  . SER B 1 223 ? 112.216 117.689 53.526  1.00 177.82 ? 223 SER B OG  1 
ATOM   5723 N N   . LEU B 1 224 ? 113.782 119.335 56.103  1.00 169.85 ? 224 LEU B N   1 
ATOM   5724 C CA  . LEU B 1 224 ? 113.337 120.377 57.017  1.00 169.85 ? 224 LEU B CA  1 
ATOM   5725 C C   . LEU B 1 224 ? 114.499 121.097 57.684  1.00 169.85 ? 224 LEU B C   1 
ATOM   5726 O O   . LEU B 1 224 ? 114.273 121.978 58.518  1.00 169.85 ? 224 LEU B O   1 
ATOM   5727 C CB  . LEU B 1 224 ? 112.405 119.794 58.086  1.00 169.85 ? 224 LEU B CB  1 
ATOM   5728 C CG  . LEU B 1 224 ? 110.899 119.856 57.808  1.00 169.85 ? 224 LEU B CG  1 
ATOM   5729 C CD1 . LEU B 1 224 ? 110.520 119.067 56.561  1.00 169.85 ? 224 LEU B CD1 1 
ATOM   5730 C CD2 . LEU B 1 224 ? 110.105 119.380 59.015  1.00 169.85 ? 224 LEU B CD2 1 
ATOM   5731 N N   . ILE B 1 225 ? 115.735 120.737 57.337  1.00 173.48 ? 225 ILE B N   1 
ATOM   5732 C CA  . ILE B 1 225 ? 116.907 121.376 57.919  1.00 173.48 ? 225 ILE B CA  1 
ATOM   5733 C C   . ILE B 1 225 ? 117.081 122.762 57.313  1.00 173.48 ? 225 ILE B C   1 
ATOM   5734 O O   . ILE B 1 225 ? 117.110 122.922 56.086  1.00 173.48 ? 225 ILE B O   1 
ATOM   5735 C CB  . ILE B 1 225 ? 118.150 120.501 57.694  1.00 173.48 ? 225 ILE B CB  1 
ATOM   5736 C CG1 . ILE B 1 225 ? 118.139 119.303 58.648  1.00 173.48 ? 225 ILE B CG1 1 
ATOM   5737 C CG2 . ILE B 1 225 ? 119.425 121.314 57.844  1.00 173.48 ? 225 ILE B CG2 1 
ATOM   5738 C CD1 . ILE B 1 225 ? 119.356 118.411 58.526  1.00 173.48 ? 225 ILE B CD1 1 
ATOM   5739 N N   . GLY B 1 226 ? 117.194 123.772 58.172  1.00 168.88 ? 226 GLY B N   1 
ATOM   5740 C CA  . GLY B 1 226 ? 117.407 125.131 57.714  1.00 168.88 ? 226 GLY B CA  1 
ATOM   5741 C C   . GLY B 1 226 ? 116.241 126.065 57.966  1.00 168.88 ? 226 GLY B C   1 
ATOM   5742 O O   . GLY B 1 226 ? 116.024 127.013 57.205  1.00 168.88 ? 226 GLY B O   1 
ATOM   5743 N N   . GLN B 1 227 ? 115.482 125.811 59.028  1.00 163.22 ? 227 GLN B N   1 
ATOM   5744 C CA  . GLN B 1 227 ? 114.353 126.647 59.411  1.00 163.22 ? 227 GLN B CA  1 
ATOM   5745 C C   . GLN B 1 227 ? 114.570 127.166 60.826  1.00 163.22 ? 227 GLN B C   1 
ATOM   5746 O O   . GLN B 1 227 ? 115.055 126.434 61.695  1.00 163.22 ? 227 GLN B O   1 
ATOM   5747 C CB  . GLN B 1 227 ? 113.034 125.872 59.321  1.00 163.22 ? 227 GLN B CB  1 
ATOM   5748 C CG  . GLN B 1 227 ? 111.792 126.746 59.364  1.00 163.22 ? 227 GLN B CG  1 
ATOM   5749 C CD  . GLN B 1 227 ? 110.510 125.935 59.389  1.00 163.22 ? 227 GLN B CD  1 
ATOM   5750 O OE1 . GLN B 1 227 ? 110.261 125.121 58.500  1.00 163.22 ? 227 GLN B OE1 1 
ATOM   5751 N NE2 . GLN B 1 227 ? 109.687 126.159 60.405  1.00 163.22 ? 227 GLN B NE2 1 
ATOM   5752 N N   . THR B 1 228 ? 114.223 128.433 61.050  1.00 159.01 ? 228 THR B N   1 
ATOM   5753 C CA  . THR B 1 228 ? 114.490 129.058 62.337  1.00 159.01 ? 228 THR B CA  1 
ATOM   5754 C C   . THR B 1 228 ? 113.613 128.454 63.433  1.00 159.01 ? 228 THR B C   1 
ATOM   5755 O O   . THR B 1 228 ? 112.501 127.971 63.186  1.00 159.01 ? 228 THR B O   1 
ATOM   5756 C CB  . THR B 1 228 ? 114.295 130.578 62.251  1.00 159.01 ? 228 THR B CB  1 
ATOM   5757 O OG1 . THR B 1 228 ? 115.095 131.220 63.252  1.00 159.01 ? 228 THR B OG1 1 
ATOM   5758 C CG2 . THR B 1 228 ? 112.841 130.973 62.447  1.00 159.01 ? 228 THR B CG2 1 
ATOM   5759 N N   . LEU B 1 229 ? 114.146 128.473 64.659  1.00 152.66 ? 229 LEU B N   1 
ATOM   5760 C CA  . LEU B 1 229 ? 113.507 127.771 65.767  1.00 152.66 ? 229 LEU B CA  1 
ATOM   5761 C C   . LEU B 1 229 ? 112.160 128.377 66.130  1.00 152.66 ? 229 LEU B C   1 
ATOM   5762 O O   . LEU B 1 229 ? 111.244 127.646 66.517  1.00 152.66 ? 229 LEU B O   1 
ATOM   5763 C CB  . LEU B 1 229 ? 114.429 127.765 66.987  1.00 152.66 ? 229 LEU B CB  1 
ATOM   5764 C CG  . LEU B 1 229 ? 115.444 126.623 67.072  1.00 152.66 ? 229 LEU B CG  1 
ATOM   5765 C CD1 . LEU B 1 229 ? 116.039 126.536 68.468  1.00 152.66 ? 229 LEU B CD1 1 
ATOM   5766 C CD2 . LEU B 1 229 ? 114.810 125.299 66.672  1.00 152.66 ? 229 LEU B CD2 1 
ATOM   5767 N N   . GLY B 1 230 ? 112.015 129.699 66.012  1.00 152.08 ? 230 GLY B N   1 
ATOM   5768 C CA  . GLY B 1 230 ? 110.728 130.315 66.300  1.00 152.08 ? 230 GLY B CA  1 
ATOM   5769 C C   . GLY B 1 230 ? 109.644 129.866 65.340  1.00 152.08 ? 230 GLY B C   1 
ATOM   5770 O O   . GLY B 1 230 ? 108.528 129.532 65.752  1.00 152.08 ? 230 GLY B O   1 
ATOM   5771 N N   . THR B 1 231 ? 109.961 129.840 64.044  1.00 152.86 ? 231 THR B N   1 
ATOM   5772 C CA  . THR B 1 231 ? 108.994 129.366 63.061  1.00 152.86 ? 231 THR B CA  1 
ATOM   5773 C C   . THR B 1 231 ? 108.707 127.880 63.233  1.00 152.86 ? 231 THR B C   1 
ATOM   5774 O O   . THR B 1 231 ? 107.566 127.450 63.045  1.00 152.86 ? 231 THR B O   1 
ATOM   5775 C CB  . THR B 1 231 ? 109.489 129.662 61.643  1.00 152.86 ? 231 THR B CB  1 
ATOM   5776 O OG1 . THR B 1 231 ? 109.759 131.063 61.516  1.00 152.86 ? 231 THR B OG1 1 
ATOM   5777 C CG2 . THR B 1 231 ? 108.439 129.275 60.612  1.00 152.86 ? 231 THR B CG2 1 
ATOM   5778 N N   . VAL B 1 232 ? 109.711 127.087 63.621  1.00 150.60 ? 232 VAL B N   1 
ATOM   5779 C CA  . VAL B 1 232 ? 109.458 125.674 63.898  1.00 150.60 ? 232 VAL B CA  1 
ATOM   5780 C C   . VAL B 1 232 ? 108.519 125.516 65.095  1.00 150.60 ? 232 VAL B C   1 
ATOM   5781 O O   . VAL B 1 232 ? 107.601 124.683 65.079  1.00 150.60 ? 232 VAL B O   1 
ATOM   5782 C CB  . VAL B 1 232 ? 110.786 124.924 64.108  1.00 150.60 ? 232 VAL B CB  1 
ATOM   5783 C CG1 . VAL B 1 232 ? 110.528 123.486 64.481  1.00 150.60 ? 232 VAL B CG1 1 
ATOM   5784 C CG2 . VAL B 1 232 ? 111.626 124.971 62.846  1.00 150.60 ? 232 VAL B CG2 1 
ATOM   5785 N N   . ASN B 1 233 ? 108.728 126.316 66.145  1.00 144.06 ? 233 ASN B N   1 
ATOM   5786 C CA  . ASN B 1 233 ? 107.856 126.257 67.315  1.00 144.06 ? 233 ASN B CA  1 
ATOM   5787 C C   . ASN B 1 233 ? 106.428 126.660 66.967  1.00 144.06 ? 233 ASN B C   1 
ATOM   5788 O O   . ASN B 1 233 ? 105.469 126.049 67.452  1.00 144.06 ? 233 ASN B O   1 
ATOM   5789 C CB  . ASN B 1 233 ? 108.408 127.142 68.432  1.00 144.06 ? 233 ASN B CB  1 
ATOM   5790 C CG  . ASN B 1 233 ? 109.739 126.646 68.964  1.00 144.06 ? 233 ASN B CG  1 
ATOM   5791 O OD1 . ASN B 1 233 ? 110.272 125.642 68.493  1.00 144.06 ? 233 ASN B OD1 1 
ATOM   5792 N ND2 . ASN B 1 233 ? 110.279 127.346 69.954  1.00 144.06 ? 233 ASN B ND2 1 
ATOM   5793 N N   . THR B 1 234 ? 106.263 127.697 66.140  1.00 148.65 ? 234 THR B N   1 
ATOM   5794 C CA  . THR B 1 234 ? 104.922 128.044 65.675  1.00 148.65 ? 234 THR B CA  1 
ATOM   5795 C C   . THR B 1 234 ? 104.338 126.958 64.778  1.00 148.65 ? 234 THR B C   1 
ATOM   5796 O O   . THR B 1 234 ? 103.116 126.778 64.743  1.00 148.65 ? 234 THR B O   1 
ATOM   5797 C CB  . THR B 1 234 ? 104.931 129.387 64.939  1.00 148.65 ? 234 THR B CB  1 
ATOM   5798 O OG1 . THR B 1 234 ? 105.695 129.273 63.732  1.00 148.65 ? 234 THR B OG1 1 
ATOM   5799 C CG2 . THR B 1 234 ? 105.504 130.486 65.821  1.00 148.65 ? 234 THR B CG2 1 
ATOM   5800 N N   . LYS B 1 235 ? 105.190 126.234 64.048  1.00 150.42 ? 235 LYS B N   1 
ATOM   5801 C CA  . LYS B 1 235 ? 104.725 125.103 63.252  1.00 150.42 ? 235 LYS B CA  1 
ATOM   5802 C C   . LYS B 1 235 ? 104.193 123.983 64.135  1.00 150.42 ? 235 LYS B C   1 
ATOM   5803 O O   . LYS B 1 235 ? 103.239 123.295 63.752  1.00 150.42 ? 235 LYS B O   1 
ATOM   5804 C CB  . LYS B 1 235 ? 105.857 124.585 62.362  1.00 150.42 ? 235 LYS B CB  1 
ATOM   5805 C CG  . LYS B 1 235 ? 105.461 123.438 61.447  1.00 150.42 ? 235 LYS B CG  1 
ATOM   5806 C CD  . LYS B 1 235 ? 106.562 123.113 60.449  1.00 150.42 ? 235 LYS B CD  1 
ATOM   5807 C CE  . LYS B 1 235 ? 107.906 122.943 61.142  1.00 150.42 ? 235 LYS B CE  1 
ATOM   5808 N NZ  . LYS B 1 235 ? 109.022 122.809 60.166  1.00 150.42 ? 235 LYS B NZ  1 
ATOM   5809 N N   . PHE B 1 236 ? 104.797 123.783 65.305  1.00 139.56 ? 236 PHE B N   1 
ATOM   5810 C CA  . PHE B 1 236 ? 104.279 122.805 66.254  1.00 139.56 ? 236 PHE B CA  1 
ATOM   5811 C C   . PHE B 1 236 ? 102.857 123.156 66.677  1.00 139.56 ? 236 PHE B C   1 
ATOM   5812 O O   . PHE B 1 236 ? 102.490 124.326 66.804  1.00 139.56 ? 236 PHE B O   1 
ATOM   5813 C CB  . PHE B 1 236 ? 105.176 122.719 67.488  1.00 139.56 ? 236 PHE B CB  1 
ATOM   5814 C CG  . PHE B 1 236 ? 106.557 122.219 67.202  1.00 139.56 ? 236 PHE B CG  1 
ATOM   5815 C CD1 . PHE B 1 236 ? 106.770 121.256 66.230  1.00 139.56 ? 236 PHE B CD1 1 
ATOM   5816 C CD2 . PHE B 1 236 ? 107.643 122.703 67.910  1.00 139.56 ? 236 PHE B CD2 1 
ATOM   5817 C CE1 . PHE B 1 236 ? 108.040 120.787 65.968  1.00 139.56 ? 236 PHE B CE1 1 
ATOM   5818 C CE2 . PHE B 1 236 ? 108.917 122.243 67.649  1.00 139.56 ? 236 PHE B CE2 1 
ATOM   5819 C CZ  . PHE B 1 236 ? 109.114 121.276 66.682  1.00 139.56 ? 236 PHE B CZ  1 
ATOM   5820 N N   . ALA B 1 237 ? 102.053 122.116 66.890  1.00 131.09 ? 237 ALA B N   1 
ATOM   5821 C CA  . ALA B 1 237 ? 100.667 122.286 67.293  1.00 131.09 ? 237 ALA B CA  1 
ATOM   5822 C C   . ALA B 1 237 ? 100.581 122.916 68.684  1.00 131.09 ? 237 ALA B C   1 
ATOM   5823 O O   . ALA B 1 237 ? 101.579 123.081 69.391  1.00 131.09 ? 237 ALA B O   1 
ATOM   5824 C CB  . ALA B 1 237 ? 99.935  120.945 67.271  1.00 131.09 ? 237 ALA B CB  1 
ATOM   5825 N N   . LYS B 1 238 ? 99.358  123.278 69.066  1.00 124.03 ? 238 LYS B N   1 
ATOM   5826 C CA  . LYS B 1 238 ? 99.127  123.913 70.358  1.00 124.03 ? 238 LYS B CA  1 
ATOM   5827 C C   . LYS B 1 238 ? 99.503  122.968 71.492  1.00 124.03 ? 238 LYS B C   1 
ATOM   5828 O O   . LYS B 1 238 ? 99.070  121.812 71.526  1.00 124.03 ? 238 LYS B O   1 
ATOM   5829 C CB  . LYS B 1 238 ? 97.661  124.331 70.482  1.00 124.03 ? 238 LYS B CB  1 
ATOM   5830 C CG  . LYS B 1 238 ? 97.089  124.978 69.229  1.00 124.03 ? 238 LYS B CG  1 
ATOM   5831 C CD  . LYS B 1 238 ? 97.863  126.228 68.839  1.00 124.03 ? 238 LYS B CD  1 
ATOM   5832 C CE  . LYS B 1 238 ? 97.951  126.369 67.327  1.00 124.03 ? 238 LYS B CE  1 
ATOM   5833 N NZ  . LYS B 1 238 ? 98.661  125.219 66.701  1.00 124.03 ? 238 LYS B NZ  1 
ATOM   5834 N N   . GLY B 1 239 ? 100.310 123.465 72.423  1.00 124.63 ? 239 GLY B N   1 
ATOM   5835 C CA  . GLY B 1 239 ? 100.796 122.666 73.525  1.00 124.63 ? 239 GLY B CA  1 
ATOM   5836 C C   . GLY B 1 239 ? 102.179 122.081 73.348  1.00 124.63 ? 239 GLY B C   1 
ATOM   5837 O O   . GLY B 1 239 ? 102.602 121.280 74.189  1.00 124.63 ? 239 GLY B O   1 
ATOM   5838 N N   . LEU B 1 240 ? 102.895 122.451 72.290  1.00 124.98 ? 240 LEU B N   1 
ATOM   5839 C CA  . LEU B 1 240 ? 104.230 121.939 72.025  1.00 124.98 ? 240 LEU B CA  1 
ATOM   5840 C C   . LEU B 1 240 ? 105.232 123.079 71.998  1.00 124.98 ? 240 LEU B C   1 
ATOM   5841 O O   . LEU B 1 240 ? 104.897 124.212 71.639  1.00 124.98 ? 240 LEU B O   1 
ATOM   5842 C CB  . LEU B 1 240 ? 104.316 121.205 70.687  1.00 124.98 ? 240 LEU B CB  1 
ATOM   5843 C CG  . LEU B 1 240 ? 104.008 119.716 70.643  1.00 124.98 ? 240 LEU B CG  1 
ATOM   5844 C CD1 . LEU B 1 240 ? 102.528 119.516 70.792  1.00 124.98 ? 240 LEU B CD1 1 
ATOM   5845 C CD2 . LEU B 1 240 ? 104.508 119.117 69.349  1.00 124.98 ? 240 LEU B CD2 1 
ATOM   5846 N N   . VAL B 1 241 ? 106.474 122.762 72.365  1.00 128.80 ? 241 VAL B N   1 
ATOM   5847 C CA  . VAL B 1 241 ? 107.585 123.680 72.157  1.00 128.80 ? 241 VAL B CA  1 
ATOM   5848 C C   . VAL B 1 241 ? 108.882 122.886 72.209  1.00 128.80 ? 241 VAL B C   1 
ATOM   5849 O O   . VAL B 1 241 ? 108.962 121.828 72.843  1.00 128.80 ? 241 VAL B O   1 
ATOM   5850 C CB  . VAL B 1 241 ? 107.569 124.841 73.185  1.00 128.80 ? 241 VAL B CB  1 
ATOM   5851 C CG1 . VAL B 1 241 ? 108.281 124.455 74.474  1.00 128.80 ? 241 VAL B CG1 1 
ATOM   5852 C CG2 . VAL B 1 241 ? 108.170 126.091 72.567  1.00 128.80 ? 241 VAL B CG2 1 
ATOM   5853 N N   . ALA B 1 242 ? 109.893 123.391 71.511  1.00 130.55 ? 242 ALA B N   1 
ATOM   5854 C CA  . ALA B 1 242 ? 111.240 122.841 71.550  1.00 130.55 ? 242 ALA B CA  1 
ATOM   5855 C C   . ALA B 1 242 ? 112.088 123.734 72.446  1.00 130.55 ? 242 ALA B C   1 
ATOM   5856 O O   . ALA B 1 242 ? 112.143 124.951 72.237  1.00 130.55 ? 242 ALA B O   1 
ATOM   5857 C CB  . ALA B 1 242 ? 111.838 122.751 70.147  1.00 130.55 ? 242 ALA B CB  1 
ATOM   5858 N N   . ALA B 1 243 ? 112.732 123.131 73.447  1.00 133.47 ? 243 ALA B N   1 
ATOM   5859 C CA  . ALA B 1 243 ? 113.512 123.912 74.401  1.00 133.47 ? 243 ALA B CA  1 
ATOM   5860 C C   . ALA B 1 243 ? 114.677 124.619 73.721  1.00 133.47 ? 243 ALA B C   1 
ATOM   5861 O O   . ALA B 1 243 ? 114.971 125.781 74.026  1.00 133.47 ? 243 ALA B O   1 
ATOM   5862 C CB  . ALA B 1 243 ? 114.010 123.013 75.531  1.00 133.47 ? 243 ALA B CB  1 
ATOM   5863 N N   . GLY B 1 244 ? 115.343 123.947 72.799  1.00 141.99 ? 244 GLY B N   1 
ATOM   5864 C CA  . GLY B 1 244 ? 116.441 124.534 72.053  1.00 141.99 ? 244 GLY B CA  1 
ATOM   5865 C C   . GLY B 1 244 ? 117.516 123.513 71.742  1.00 141.99 ? 244 GLY B C   1 
ATOM   5866 O O   . GLY B 1 244 ? 117.578 122.429 72.323  1.00 141.99 ? 244 GLY B O   1 
ATOM   5867 N N   . LEU B 1 245 ? 118.382 123.871 70.797  1.00 150.34 ? 245 LEU B N   1 
ATOM   5868 C CA  . LEU B 1 245 ? 119.468 122.990 70.392  1.00 150.34 ? 245 LEU B CA  1 
ATOM   5869 C C   . LEU B 1 245 ? 120.495 122.856 71.510  1.00 150.34 ? 245 LEU B C   1 
ATOM   5870 O O   . LEU B 1 245 ? 120.828 123.834 72.186  1.00 150.34 ? 245 LEU B O   1 
ATOM   5871 C CB  . LEU B 1 245 ? 120.135 123.525 69.126  1.00 150.34 ? 245 LEU B CB  1 
ATOM   5872 C CG  . LEU B 1 245 ? 119.253 123.678 67.883  1.00 150.34 ? 245 LEU B CG  1 
ATOM   5873 C CD1 . LEU B 1 245 ? 120.111 123.885 66.647  1.00 150.34 ? 245 LEU B CD1 1 
ATOM   5874 C CD2 . LEU B 1 245 ? 118.341 122.472 67.706  1.00 150.34 ? 245 LEU B CD2 1 
ATOM   5875 N N   . ASN B 1 246 ? 121.013 121.636 71.678  1.00 150.43 ? 246 ASN B N   1 
ATOM   5876 C CA  . ASN B 1 246 ? 121.963 121.269 72.743  1.00 150.43 ? 246 ASN B CA  1 
ATOM   5877 C C   . ASN B 1 246 ? 121.358 121.700 74.079  1.00 150.43 ? 246 ASN B C   1 
ATOM   5878 O O   . ASN B 1 246 ? 120.211 121.333 74.370  1.00 150.43 ? 246 ASN B O   1 
ATOM   5879 C CB  . ASN B 1 246 ? 123.335 121.851 72.427  1.00 150.43 ? 246 ASN B CB  1 
ATOM   5880 C CG  . ASN B 1 246 ? 123.614 121.921 70.939  1.00 150.43 ? 246 ASN B CG  1 
ATOM   5881 O OD1 . ASN B 1 246 ? 123.675 120.896 70.259  1.00 150.43 ? 246 ASN B OD1 1 
ATOM   5882 N ND2 . ASN B 1 246 ? 123.784 123.132 70.423  1.00 150.43 ? 246 ASN B ND2 1 
ATOM   5883 N N   . ASP B 1 247 ? 122.071 122.461 74.907  1.00 149.26 ? 247 ASP B N   1 
ATOM   5884 C CA  . ASP B 1 247 ? 121.520 123.019 76.134  1.00 149.26 ? 247 ASP B CA  1 
ATOM   5885 C C   . ASP B 1 247 ? 121.301 124.522 76.033  1.00 149.26 ? 247 ASP B C   1 
ATOM   5886 O O   . ASP B 1 247 ? 121.086 125.179 77.057  1.00 149.26 ? 247 ASP B O   1 
ATOM   5887 C CB  . ASP B 1 247 ? 122.432 122.697 77.319  1.00 149.26 ? 247 ASP B CB  1 
ATOM   5888 C CG  . ASP B 1 247 ? 122.476 121.215 77.636  1.00 149.26 ? 247 ASP B CG  1 
ATOM   5889 O OD1 . ASP B 1 247 ? 121.853 120.428 76.893  1.00 149.26 ? 247 ASP B OD1 1 
ATOM   5890 O OD2 . ASP B 1 247 ? 123.131 120.836 78.629  1.00 149.26 ? 247 ASP B OD2 1 
ATOM   5891 N N   . SER B 1 248 ? 121.350 125.080 74.828  1.00 151.45 ? 248 SER B N   1 
ATOM   5892 C CA  . SER B 1 248 ? 121.190 126.509 74.618  1.00 151.45 ? 248 SER B CA  1 
ATOM   5893 C C   . SER B 1 248 ? 119.737 126.850 74.305  1.00 151.45 ? 248 SER B C   1 
ATOM   5894 O O   . SER B 1 248 ? 118.945 126.001 73.890  1.00 151.45 ? 248 SER B O   1 
ATOM   5895 C CB  . SER B 1 248 ? 122.094 126.991 73.484  1.00 151.45 ? 248 SER B CB  1 
ATOM   5896 O OG  . SER B 1 248 ? 121.615 126.543 72.227  1.00 151.45 ? 248 SER B OG  1 
ATOM   5897 N N   . ALA B 1 249 ? 119.394 128.121 74.512  1.00 149.92 ? 249 ALA B N   1 
ATOM   5898 C CA  . ALA B 1 249 ? 118.061 128.651 74.225  1.00 149.92 ? 249 ALA B CA  1 
ATOM   5899 C C   . ALA B 1 249 ? 118.240 129.903 73.370  1.00 149.92 ? 249 ALA B C   1 
ATOM   5900 O O   . ALA B 1 249 ? 118.337 131.016 73.894  1.00 149.92 ? 249 ALA B O   1 
ATOM   5901 C CB  . ALA B 1 249 ? 117.293 128.946 75.508  1.00 149.92 ? 249 ALA B CB  1 
ATOM   5902 N N   . ASP B 1 250 ? 118.285 129.715 72.054  1.00 157.13 ? 250 ASP B N   1 
ATOM   5903 C CA  . ASP B 1 250 ? 118.445 130.807 71.106  1.00 157.13 ? 250 ASP B CA  1 
ATOM   5904 C C   . ASP B 1 250 ? 117.298 130.770 70.106  1.00 157.13 ? 250 ASP B C   1 
ATOM   5905 O O   . ASP B 1 250 ? 116.901 129.697 69.640  1.00 157.13 ? 250 ASP B O   1 
ATOM   5906 C CB  . ASP B 1 250 ? 119.797 130.716 70.385  1.00 157.13 ? 250 ASP B CB  1 
ATOM   5907 C CG  . ASP B 1 250 ? 119.857 131.577 69.139  1.00 157.13 ? 250 ASP B CG  1 
ATOM   5908 O OD1 . ASP B 1 250 ? 119.392 132.736 69.183  1.00 157.13 ? 250 ASP B OD1 1 
ATOM   5909 O OD2 . ASP B 1 250 ? 120.384 131.097 68.115  1.00 157.13 ? 250 ASP B OD2 1 
ATOM   5910 N N   . MET B 1 251 ? 116.762 131.951 69.787  1.00 157.47 ? 251 MET B N   1 
ATOM   5911 C CA  . MET B 1 251 ? 115.570 132.027 68.949  1.00 157.47 ? 251 MET B CA  1 
ATOM   5912 C C   . MET B 1 251 ? 115.865 131.640 67.505  1.00 157.47 ? 251 MET B C   1 
ATOM   5913 O O   . MET B 1 251 ? 115.044 130.984 66.854  1.00 157.47 ? 251 MET B O   1 
ATOM   5914 C CB  . MET B 1 251 ? 114.975 133.432 69.012  1.00 157.47 ? 251 MET B CB  1 
ATOM   5915 C CG  . MET B 1 251 ? 114.030 133.639 70.176  1.00 157.47 ? 251 MET B CG  1 
ATOM   5916 S SD  . MET B 1 251 ? 113.199 132.111 70.639  1.00 157.47 ? 251 MET B SD  1 
ATOM   5917 C CE  . MET B 1 251 ? 112.208 132.690 72.007  1.00 157.47 ? 251 MET B CE  1 
ATOM   5918 N N   . ALA B 1 252 ? 117.025 132.032 66.986  1.00 162.64 ? 252 ALA B N   1 
ATOM   5919 C CA  . ALA B 1 252 ? 117.365 131.827 65.579  1.00 162.64 ? 252 ALA B CA  1 
ATOM   5920 C C   . ALA B 1 252 ? 118.628 130.973 65.497  1.00 162.64 ? 252 ALA B C   1 
ATOM   5921 O O   . ALA B 1 252 ? 119.739 131.495 65.383  1.00 162.64 ? 252 ALA B O   1 
ATOM   5922 C CB  . ALA B 1 252 ? 117.546 133.164 64.862  1.00 162.64 ? 252 ALA B CB  1 
ATOM   5923 N N   . SER B 1 253 ? 118.445 129.655 65.543  1.00 165.85 ? 253 SER B N   1 
ATOM   5924 C CA  . SER B 1 253 ? 119.538 128.697 65.373  1.00 165.85 ? 253 SER B CA  1 
ATOM   5925 C C   . SER B 1 253 ? 118.997 127.561 64.513  1.00 165.85 ? 253 SER B C   1 
ATOM   5926 O O   . SER B 1 253 ? 118.349 126.643 65.025  1.00 165.85 ? 253 SER B O   1 
ATOM   5927 C CB  . SER B 1 253 ? 120.056 128.187 66.712  1.00 165.85 ? 253 SER B CB  1 
ATOM   5928 O OG  . SER B 1 253 ? 118.999 127.691 67.515  1.00 165.85 ? 253 SER B OG  1 
ATOM   5929 N N   . VAL B 1 254 ? 119.254 127.636 63.204  1.00 169.70 ? 254 VAL B N   1 
ATOM   5930 C CA  . VAL B 1 254 ? 118.727 126.633 62.288  1.00 169.70 ? 254 VAL B CA  1 
ATOM   5931 C C   . VAL B 1 254 ? 119.361 125.272 62.568  1.00 169.70 ? 254 VAL B C   1 
ATOM   5932 O O   . VAL B 1 254 ? 120.428 125.159 63.184  1.00 169.70 ? 254 VAL B O   1 
ATOM   5933 C CB  . VAL B 1 254 ? 118.950 127.050 60.826  1.00 169.70 ? 254 VAL B CB  1 
ATOM   5934 C CG1 . VAL B 1 254 ? 118.081 128.248 60.482  1.00 169.70 ? 254 VAL B CG1 1 
ATOM   5935 C CG2 . VAL B 1 254 ? 120.418 127.362 60.581  1.00 169.70 ? 254 VAL B CG2 1 
ATOM   5936 N N   . ILE B 1 255 ? 118.676 124.224 62.112  1.00 172.94 ? 255 ILE B N   1 
ATOM   5937 C CA  . ILE B 1 255 ? 119.143 122.860 62.316  1.00 172.94 ? 255 ILE B CA  1 
ATOM   5938 C C   . ILE B 1 255 ? 120.439 122.649 61.547  1.00 172.94 ? 255 ILE B C   1 
ATOM   5939 O O   . ILE B 1 255 ? 120.529 122.969 60.355  1.00 172.94 ? 255 ILE B O   1 
ATOM   5940 C CB  . ILE B 1 255 ? 118.066 121.860 61.871  1.00 172.94 ? 255 ILE B CB  1 
ATOM   5941 C CG1 . ILE B 1 255 ? 116.709 122.245 62.471  1.00 172.94 ? 255 ILE B CG1 1 
ATOM   5942 C CG2 . ILE B 1 255 ? 118.462 120.449 62.264  1.00 172.94 ? 255 ILE B CG2 1 
ATOM   5943 C CD1 . ILE B 1 255 ? 115.617 121.233 62.223  1.00 172.94 ? 255 ILE B CD1 1 
ATOM   5944 N N   . ASN B 1 256 ? 121.460 122.129 62.230  1.00 174.11 ? 256 ASN B N   1 
ATOM   5945 C CA  . ASN B 1 256 ? 122.724 121.870 61.552  1.00 174.11 ? 256 ASN B CA  1 
ATOM   5946 C C   . ASN B 1 256 ? 122.821 120.424 61.080  1.00 174.11 ? 256 ASN B C   1 
ATOM   5947 O O   . ASN B 1 256 ? 122.830 120.166 59.871  1.00 174.11 ? 256 ASN B O   1 
ATOM   5948 C CB  . ASN B 1 256 ? 123.896 122.210 62.477  1.00 174.11 ? 256 ASN B CB  1 
ATOM   5949 C CG  . ASN B 1 256 ? 123.645 121.793 63.915  1.00 174.11 ? 256 ASN B CG  1 
ATOM   5950 O OD1 . ASN B 1 256 ? 122.551 121.346 64.261  1.00 174.11 ? 256 ASN B OD1 1 
ATOM   5951 N ND2 . ASN B 1 256 ? 124.660 121.934 64.760  1.00 174.11 ? 256 ASN B ND2 1 
ATOM   5952 N N   . ALA B 1 257 ? 122.859 119.480 62.024  1.00 170.74 ? 257 ALA B N   1 
ATOM   5953 C CA  . ALA B 1 257 ? 122.870 118.051 61.726  1.00 170.74 ? 257 ALA B CA  1 
ATOM   5954 C C   . ALA B 1 257 ? 122.678 117.234 62.996  1.00 170.74 ? 257 ALA B C   1 
ATOM   5955 O O   . ALA B 1 257 ? 123.432 117.403 63.961  1.00 170.74 ? 257 ALA B O   1 
ATOM   5956 C CB  . ALA B 1 257 ? 124.179 117.638 61.046  1.00 170.74 ? 257 ALA B CB  1 
ATOM   5957 N N   . GLY B 1 258 ? 121.693 116.337 62.998  1.00 162.37 ? 258 GLY B N   1 
ATOM   5958 C CA  . GLY B 1 258 ? 121.526 115.383 64.083  1.00 162.37 ? 258 GLY B CA  1 
ATOM   5959 C C   . GLY B 1 258 ? 121.364 115.988 65.460  1.00 162.37 ? 258 GLY B C   1 
ATOM   5960 O O   . GLY B 1 258 ? 121.679 115.331 66.458  1.00 162.37 ? 258 GLY B O   1 
ATOM   5961 N N   . ASP B 1 259 ? 120.880 117.223 65.547  1.00 155.90 ? 259 ASP B N   1 
ATOM   5962 C CA  . ASP B 1 259 ? 120.765 117.894 66.831  1.00 155.90 ? 259 ASP B CA  1 
ATOM   5963 C C   . ASP B 1 259 ? 119.405 117.608 67.464  1.00 155.90 ? 259 ASP B C   1 
ATOM   5964 O O   . ASP B 1 259 ? 118.465 117.159 66.808  1.00 155.90 ? 259 ASP B O   1 
ATOM   5965 C CB  . ASP B 1 259 ? 120.989 119.396 66.670  1.00 155.90 ? 259 ASP B CB  1 
ATOM   5966 C CG  . ASP B 1 259 ? 121.604 120.023 67.901  1.00 155.90 ? 259 ASP B CG  1 
ATOM   5967 O OD1 . ASP B 1 259 ? 121.770 119.304 68.908  1.00 155.90 ? 259 ASP B OD1 1 
ATOM   5968 O OD2 . ASP B 1 259 ? 121.941 121.223 67.856  1.00 155.90 ? 259 ASP B OD2 1 
ATOM   5969 N N   . VAL B 1 260 ? 119.304 117.889 68.761  1.00 147.53 ? 260 VAL B N   1 
ATOM   5970 C CA  . VAL B 1 260 ? 118.133 117.529 69.554  1.00 147.53 ? 260 VAL B CA  1 
ATOM   5971 C C   . VAL B 1 260 ? 117.141 118.686 69.558  1.00 147.53 ? 260 VAL B C   1 
ATOM   5972 O O   . VAL B 1 260 ? 117.530 119.862 69.552  1.00 147.53 ? 260 VAL B O   1 
ATOM   5973 C CB  . VAL B 1 260 ? 118.534 117.112 70.986  1.00 147.53 ? 260 VAL B CB  1 
ATOM   5974 C CG1 . VAL B 1 260 ? 119.725 116.165 70.944  1.00 147.53 ? 260 VAL B CG1 1 
ATOM   5975 C CG2 . VAL B 1 260 ? 118.855 118.319 71.857  1.00 147.53 ? 260 VAL B CG2 1 
ATOM   5976 N N   . LEU B 1 261 ? 115.852 118.349 69.503  1.00 137.08 ? 261 LEU B N   1 
ATOM   5977 C CA  . LEU B 1 261 ? 114.796 119.345 69.631  1.00 137.08 ? 261 LEU B CA  1 
ATOM   5978 C C   . LEU B 1 261 ? 114.309 119.503 71.063  1.00 137.08 ? 261 LEU B C   1 
ATOM   5979 O O   . LEU B 1 261 ? 113.900 120.605 71.446  1.00 137.08 ? 261 LEU B O   1 
ATOM   5980 C CB  . LEU B 1 261 ? 113.602 118.994 68.734  1.00 137.08 ? 261 LEU B CB  1 
ATOM   5981 C CG  . LEU B 1 261 ? 113.600 119.326 67.235  1.00 137.08 ? 261 LEU B CG  1 
ATOM   5982 C CD1 . LEU B 1 261 ? 113.392 120.820 67.023  1.00 137.08 ? 261 LEU B CD1 1 
ATOM   5983 C CD2 . LEU B 1 261 ? 114.847 118.848 66.511  1.00 137.08 ? 261 LEU B CD2 1 
ATOM   5984 N N   . ALA B 1 262 ? 114.352 118.427 71.855  1.00 126.81 ? 262 ALA B N   1 
ATOM   5985 C CA  . ALA B 1 262 ? 113.843 118.416 73.229  1.00 126.81 ? 262 ALA B CA  1 
ATOM   5986 C C   . ALA B 1 262 ? 112.382 118.864 73.278  1.00 126.81 ? 262 ALA B C   1 
ATOM   5987 O O   . ALA B 1 262 ? 112.024 119.833 73.951  1.00 126.81 ? 262 ALA B O   1 
ATOM   5988 C CB  . ALA B 1 262 ? 114.714 119.267 74.154  1.00 126.81 ? 262 ALA B CB  1 
ATOM   5989 N N   . ILE B 1 263 ? 111.538 118.144 72.542  1.00 119.72 ? 263 ILE B N   1 
ATOM   5990 C CA  . ILE B 1 263 ? 110.124 118.481 72.443  1.00 119.72 ? 263 ILE B CA  1 
ATOM   5991 C C   . ILE B 1 263 ? 109.451 118.273 73.794  1.00 119.72 ? 263 ILE B C   1 
ATOM   5992 O O   . ILE B 1 263 ? 109.678 117.261 74.471  1.00 119.72 ? 263 ILE B O   1 
ATOM   5993 C CB  . ILE B 1 263 ? 109.462 117.641 71.340  1.00 119.72 ? 263 ILE B CB  1 
ATOM   5994 C CG1 . ILE B 1 263 ? 109.629 118.324 69.986  1.00 119.72 ? 263 ILE B CG1 1 
ATOM   5995 C CG2 . ILE B 1 263 ? 107.989 117.420 71.622  1.00 119.72 ? 263 ILE B CG2 1 
ATOM   5996 C CD1 . ILE B 1 263 ? 108.801 119.567 69.849  1.00 119.72 ? 263 ILE B CD1 1 
ATOM   5997 N N   . SER B 1 264 ? 108.629 119.240 74.202  1.00 114.70 ? 264 SER B N   1 
ATOM   5998 C CA  . SER B 1 264 ? 107.889 119.160 75.451  1.00 114.70 ? 264 SER B CA  1 
ATOM   5999 C C   . SER B 1 264 ? 106.397 119.282 75.173  1.00 114.70 ? 264 SER B C   1 
ATOM   6000 O O   . SER B 1 264 ? 105.970 120.129 74.383  1.00 114.70 ? 264 SER B O   1 
ATOM   6001 C CB  . SER B 1 264 ? 108.331 120.257 76.422  1.00 114.70 ? 264 SER B CB  1 
ATOM   6002 O OG  . SER B 1 264 ? 108.121 121.539 75.861  1.00 114.70 ? 264 SER B OG  1 
ATOM   6003 N N   . GLY B 1 265 ? 105.610 118.430 75.821  1.00 114.67 ? 265 GLY B N   1 
ATOM   6004 C CA  . GLY B 1 265 ? 104.169 118.464 75.657  1.00 114.67 ? 265 GLY B CA  1 
ATOM   6005 C C   . GLY B 1 265 ? 103.554 117.122 76.020  1.00 114.67 ? 265 GLY B C   1 
ATOM   6006 O O   . GLY B 1 265 ? 104.202 116.272 76.627  1.00 114.67 ? 265 GLY B O   1 
ATOM   6007 N N   . GLY B 1 266 ? 102.289 116.966 75.634  1.00 121.64 ? 266 GLY B N   1 
ATOM   6008 C CA  . GLY B 1 266 ? 101.586 115.723 75.892  1.00 121.64 ? 266 GLY B CA  1 
ATOM   6009 C C   . GLY B 1 266 ? 102.044 114.609 74.970  1.00 121.64 ? 266 GLY B C   1 
ATOM   6010 O O   . GLY B 1 266 ? 102.508 114.845 73.857  1.00 121.64 ? 266 GLY B O   1 
ATOM   6011 N N   . ILE B 1 267 ? 101.897 113.370 75.448  1.00 120.21 ? 267 ILE B N   1 
ATOM   6012 C CA  . ILE B 1 267 ? 102.468 112.215 74.754  1.00 120.21 ? 267 ILE B CA  1 
ATOM   6013 C C   . ILE B 1 267 ? 101.841 112.043 73.373  1.00 120.21 ? 267 ILE B C   1 
ATOM   6014 O O   . ILE B 1 267 ? 102.542 111.856 72.371  1.00 120.21 ? 267 ILE B O   1 
ATOM   6015 C CB  . ILE B 1 267 ? 102.309 110.946 75.614  1.00 120.21 ? 267 ILE B CB  1 
ATOM   6016 C CG1 . ILE B 1 267 ? 103.416 110.872 76.666  1.00 120.21 ? 267 ILE B CG1 1 
ATOM   6017 C CG2 . ILE B 1 267 ? 102.317 109.696 74.754  1.00 120.21 ? 267 ILE B CG2 1 
ATOM   6018 C CD1 . ILE B 1 267 ? 103.317 109.664 77.577  1.00 120.21 ? 267 ILE B CD1 1 
ATOM   6019 N N   . ASP B 1 268 ? 100.510 112.115 73.298  1.00 127.12 ? 268 ASP B N   1 
ATOM   6020 C CA  . ASP B 1 268 ? 99.828  111.961 72.016  1.00 127.12 ? 268 ASP B CA  1 
ATOM   6021 C C   . ASP B 1 268 ? 100.177 113.104 71.070  1.00 127.12 ? 268 ASP B C   1 
ATOM   6022 O O   . ASP B 1 268 ? 100.300 112.912 69.851  1.00 127.12 ? 268 ASP B O   1 
ATOM   6023 C CB  . ASP B 1 268 ? 98.318  111.883 72.247  1.00 127.12 ? 268 ASP B CB  1 
ATOM   6024 C CG  . ASP B 1 268 ? 97.591  111.148 71.138  1.00 127.12 ? 268 ASP B CG  1 
ATOM   6025 O OD1 . ASP B 1 268 ? 97.780  111.506 69.959  1.00 127.12 ? 268 ASP B OD1 1 
ATOM   6026 O OD2 . ASP B 1 268 ? 96.827  110.208 71.446  1.00 127.12 ? 268 ASP B OD2 1 
ATOM   6027 N N   . GLU B 1 269 ? 100.331 114.307 71.620  1.00 127.86 ? 269 GLU B N   1 
ATOM   6028 C CA  . GLU B 1 269 ? 100.703 115.464 70.814  1.00 127.86 ? 269 GLU B CA  1 
ATOM   6029 C C   . GLU B 1 269 ? 102.102 115.297 70.228  1.00 127.86 ? 269 GLU B C   1 
ATOM   6030 O O   . GLU B 1 269 ? 102.328 115.584 69.044  1.00 127.86 ? 269 GLU B O   1 
ATOM   6031 C CB  . GLU B 1 269 ? 100.597 116.720 71.677  1.00 127.86 ? 269 GLU B CB  1 
ATOM   6032 C CG  . GLU B 1 269 ? 99.165  117.078 72.054  1.00 127.86 ? 269 GLU B CG  1 
ATOM   6033 C CD  . GLU B 1 269 ? 99.051  118.401 72.790  1.00 127.86 ? 269 GLU B CD  1 
ATOM   6034 O OE1 . GLU B 1 269 ? 99.992  119.214 72.727  1.00 127.86 ? 269 GLU B OE1 1 
ATOM   6035 O OE2 . GLU B 1 269 ? 98.006  118.628 73.437  1.00 127.86 ? 269 GLU B OE2 1 
ATOM   6036 N N   . ILE B 1 270 ? 103.044 114.796 71.032  1.00 124.66 ? 270 ILE B N   1 
ATOM   6037 C CA  . ILE B 1 270 ? 104.382 114.499 70.528  1.00 124.66 ? 270 ILE B CA  1 
ATOM   6038 C C   . ILE B 1 270 ? 104.321 113.403 69.473  1.00 124.66 ? 270 ILE B C   1 
ATOM   6039 O O   . ILE B 1 270 ? 105.079 113.418 68.499  1.00 124.66 ? 270 ILE B O   1 
ATOM   6040 C CB  . ILE B 1 270 ? 105.335 114.121 71.681  1.00 124.66 ? 270 ILE B CB  1 
ATOM   6041 C CG1 . ILE B 1 270 ? 105.375 115.216 72.748  1.00 124.66 ? 270 ILE B CG1 1 
ATOM   6042 C CG2 . ILE B 1 270 ? 106.740 113.853 71.161  1.00 124.66 ? 270 ILE B CG2 1 
ATOM   6043 C CD1 . ILE B 1 270 ? 105.770 114.716 74.121  1.00 124.66 ? 270 ILE B CD1 1 
ATOM   6044 N N   . GLY B 1 271 ? 103.422 112.434 69.652  1.00 129.46 ? 271 GLY B N   1 
ATOM   6045 C CA  . GLY B 1 271 ? 103.279 111.384 68.656  1.00 129.46 ? 271 GLY B CA  1 
ATOM   6046 C C   . GLY B 1 271 ? 102.823 111.906 67.307  1.00 129.46 ? 271 GLY B C   1 
ATOM   6047 O O   . GLY B 1 271 ? 103.382 111.542 66.265  1.00 129.46 ? 271 GLY B O   1 
ATOM   6048 N N   . ARG B 1 272 ? 101.803 112.773 67.302  1.00 132.12 ? 272 ARG B N   1 
ATOM   6049 C CA  . ARG B 1 272 ? 101.388 113.372 66.035  1.00 132.12 ? 272 ARG B CA  1 
ATOM   6050 C C   . ARG B 1 272 ? 102.479 114.268 65.464  1.00 132.12 ? 272 ARG B C   1 
ATOM   6051 O O   . ARG B 1 272 ? 102.630 114.367 64.242  1.00 132.12 ? 272 ARG B O   1 
ATOM   6052 C CB  . ARG B 1 272 ? 100.075 114.147 66.160  1.00 132.12 ? 272 ARG B CB  1 
ATOM   6053 C CG  . ARG B 1 272 ? 98.843  113.270 65.985  1.00 132.12 ? 272 ARG B CG  1 
ATOM   6054 C CD  . ARG B 1 272 ? 97.536  113.987 66.301  1.00 132.12 ? 272 ARG B CD  1 
ATOM   6055 N NE  . ARG B 1 272 ? 97.652  115.048 67.294  1.00 132.12 ? 272 ARG B NE  1 
ATOM   6056 C CZ  . ARG B 1 272 ? 97.702  114.846 68.602  1.00 132.12 ? 272 ARG B CZ  1 
ATOM   6057 N NH1 . ARG B 1 272 ? 97.674  113.631 69.115  1.00 132.12 ? 272 ARG B NH1 1 
ATOM   6058 N NH2 . ARG B 1 272 ? 97.768  115.891 69.415  1.00 132.12 ? 272 ARG B NH2 1 
ATOM   6059 N N   . ALA B 1 273 ? 103.262 114.920 66.329  1.00 135.70 ? 273 ALA B N   1 
ATOM   6060 C CA  . ALA B 1 273 ? 104.391 115.708 65.836  1.00 135.70 ? 273 ALA B CA  1 
ATOM   6061 C C   . ALA B 1 273 ? 105.422 114.829 65.134  1.00 135.70 ? 273 ALA B C   1 
ATOM   6062 O O   . ALA B 1 273 ? 105.936 115.188 64.066  1.00 135.70 ? 273 ALA B O   1 
ATOM   6063 C CB  . ALA B 1 273 ? 105.042 116.470 66.989  1.00 135.70 ? 273 ALA B CB  1 
ATOM   6064 N N   . VAL B 1 274 ? 105.739 113.677 65.728  1.00 139.49 ? 274 VAL B N   1 
ATOM   6065 C CA  . VAL B 1 274 ? 106.714 112.760 65.139  1.00 139.49 ? 274 VAL B CA  1 
ATOM   6066 C C   . VAL B 1 274 ? 106.200 112.216 63.814  1.00 139.49 ? 274 VAL B C   1 
ATOM   6067 O O   . VAL B 1 274 ? 106.965 112.056 62.854  1.00 139.49 ? 274 VAL B O   1 
ATOM   6068 C CB  . VAL B 1 274 ? 107.058 111.629 66.127  1.00 139.49 ? 274 VAL B CB  1 
ATOM   6069 C CG1 . VAL B 1 274 ? 107.975 110.603 65.475  1.00 139.49 ? 274 VAL B CG1 1 
ATOM   6070 C CG2 . VAL B 1 274 ? 107.738 112.201 67.353  1.00 139.49 ? 274 VAL B CG2 1 
ATOM   6071 N N   . GLN B 1 275 ? 104.902 111.920 63.732  1.00 141.79 ? 275 GLN B N   1 
ATOM   6072 C CA  . GLN B 1 275 ? 104.367 111.481 62.446  1.00 141.79 ? 275 GLN B CA  1 
ATOM   6073 C C   . GLN B 1 275 ? 104.345 112.606 61.419  1.00 141.79 ? 275 GLN B C   1 
ATOM   6074 O O   . GLN B 1 275 ? 104.491 112.346 60.219  1.00 141.79 ? 275 GLN B O   1 
ATOM   6075 C CB  . GLN B 1 275 ? 102.978 110.877 62.612  1.00 141.79 ? 275 GLN B CB  1 
ATOM   6076 C CG  . GLN B 1 275 ? 103.008 109.587 63.381  1.00 141.79 ? 275 GLN B CG  1 
ATOM   6077 C CD  . GLN B 1 275 ? 102.105 108.546 62.769  1.00 141.79 ? 275 GLN B CD  1 
ATOM   6078 O OE1 . GLN B 1 275 ? 101.419 108.803 61.780  1.00 141.79 ? 275 GLN B OE1 1 
ATOM   6079 N NE2 . GLN B 1 275 ? 102.137 107.347 63.321  1.00 141.79 ? 275 GLN B NE2 1 
ATOM   6080 N N   . GLU B 1 276 ? 104.156 113.853 61.857  1.00 150.81 ? 276 GLU B N   1 
ATOM   6081 C CA  . GLU B 1 276 ? 104.258 114.974 60.930  1.00 150.81 ? 276 GLU B CA  1 
ATOM   6082 C C   . GLU B 1 276 ? 105.676 115.110 60.388  1.00 150.81 ? 276 GLU B C   1 
ATOM   6083 O O   . GLU B 1 276 ? 105.872 115.347 59.190  1.00 150.81 ? 276 GLU B O   1 
ATOM   6084 C CB  . GLU B 1 276 ? 103.816 116.268 61.615  1.00 150.81 ? 276 GLU B CB  1 
ATOM   6085 C CG  . GLU B 1 276 ? 104.104 117.524 60.808  1.00 150.81 ? 276 GLU B CG  1 
ATOM   6086 C CD  . GLU B 1 276 ? 104.217 118.765 61.670  1.00 150.81 ? 276 GLU B CD  1 
ATOM   6087 O OE1 . GLU B 1 276 ? 104.211 118.634 62.912  1.00 150.81 ? 276 GLU B OE1 1 
ATOM   6088 O OE2 . GLU B 1 276 ? 104.316 119.874 61.104  1.00 150.81 ? 276 GLU B OE2 1 
ATOM   6089 N N   . PHE B 1 277 ? 106.679 114.954 61.252  1.00 154.82 ? 277 PHE B N   1 
ATOM   6090 C CA  . PHE B 1 277 ? 108.076 115.037 60.837  1.00 154.82 ? 277 PHE B CA  1 
ATOM   6091 C C   . PHE B 1 277 ? 108.883 114.058 61.676  1.00 154.82 ? 277 PHE B C   1 
ATOM   6092 O O   . PHE B 1 277 ? 108.877 114.144 62.908  1.00 154.82 ? 277 PHE B O   1 
ATOM   6093 C CB  . PHE B 1 277 ? 108.608 116.467 60.984  1.00 154.82 ? 277 PHE B CB  1 
ATOM   6094 C CG  . PHE B 1 277 ? 110.098 116.553 61.152  1.00 154.82 ? 277 PHE B CG  1 
ATOM   6095 C CD1 . PHE B 1 277 ? 110.949 116.088 60.161  1.00 154.82 ? 277 PHE B CD1 1 
ATOM   6096 C CD2 . PHE B 1 277 ? 110.647 117.117 62.290  1.00 154.82 ? 277 PHE B CD2 1 
ATOM   6097 C CE1 . PHE B 1 277 ? 112.317 116.172 60.310  1.00 154.82 ? 277 PHE B CE1 1 
ATOM   6098 C CE2 . PHE B 1 277 ? 112.015 117.205 62.442  1.00 154.82 ? 277 PHE B CE2 1 
ATOM   6099 C CZ  . PHE B 1 277 ? 112.850 116.731 61.451  1.00 154.82 ? 277 PHE B CZ  1 
ATOM   6100 N N   . ASN B 1 278 ? 109.577 113.137 61.007  1.00 155.46 ? 278 ASN B N   1 
ATOM   6101 C CA  . ASN B 1 278 ? 110.249 112.038 61.690  1.00 155.46 ? 278 ASN B CA  1 
ATOM   6102 C C   . ASN B 1 278 ? 111.414 112.538 62.538  1.00 155.46 ? 278 ASN B C   1 
ATOM   6103 O O   . ASN B 1 278 ? 112.115 113.484 62.169  1.00 155.46 ? 278 ASN B O   1 
ATOM   6104 C CB  . ASN B 1 278 ? 110.748 111.015 60.667  1.00 155.46 ? 278 ASN B CB  1 
ATOM   6105 C CG  . ASN B 1 278 ? 111.235 109.729 61.310  1.00 155.46 ? 278 ASN B CG  1 
ATOM   6106 O OD1 . ASN B 1 278 ? 111.079 109.520 62.514  1.00 155.46 ? 278 ASN B OD1 1 
ATOM   6107 N ND2 . ASN B 1 278 ? 111.833 108.858 60.505  1.00 155.46 ? 278 ASN B ND2 1 
ATOM   6108 N N   . LEU B 1 279 ? 111.619 111.882 63.680  1.00 147.75 ? 279 LEU B N   1 
ATOM   6109 C CA  . LEU B 1 279 ? 112.668 112.248 64.622  1.00 147.75 ? 279 LEU B CA  1 
ATOM   6110 C C   . LEU B 1 279 ? 113.148 110.991 65.335  1.00 147.75 ? 279 LEU B C   1 
ATOM   6111 O O   . LEU B 1 279 ? 112.407 110.016 65.477  1.00 147.75 ? 279 LEU B O   1 
ATOM   6112 C CB  . LEU B 1 279 ? 112.166 113.286 65.632  1.00 147.75 ? 279 LEU B CB  1 
ATOM   6113 C CG  . LEU B 1 279 ? 112.169 114.748 65.184  1.00 147.75 ? 279 LEU B CG  1 
ATOM   6114 C CD1 . LEU B 1 279 ? 111.492 115.639 66.212  1.00 147.75 ? 279 LEU B CD1 1 
ATOM   6115 C CD2 . LEU B 1 279 ? 113.595 115.211 64.935  1.00 147.75 ? 279 LEU B CD2 1 
ATOM   6116 N N   . LEU B 1 280 ? 114.404 111.020 65.783  1.00 144.83 ? 280 LEU B N   1 
ATOM   6117 C CA  . LEU B 1 280 ? 115.011 109.890 66.479  1.00 144.83 ? 280 LEU B CA  1 
ATOM   6118 C C   . LEU B 1 280 ? 114.844 110.092 67.979  1.00 144.83 ? 280 LEU B C   1 
ATOM   6119 O O   . LEU B 1 280 ? 115.368 111.062 68.534  1.00 144.83 ? 280 LEU B O   1 
ATOM   6120 C CB  . LEU B 1 280 ? 116.501 109.753 66.153  1.00 144.83 ? 280 LEU B CB  1 
ATOM   6121 C CG  . LEU B 1 280 ? 117.118 109.303 64.820  1.00 144.83 ? 280 LEU B CG  1 
ATOM   6122 C CD1 . LEU B 1 280 ? 116.851 107.824 64.549  1.00 144.83 ? 280 LEU B CD1 1 
ATOM   6123 C CD2 . LEU B 1 280 ? 116.733 110.187 63.635  1.00 144.83 ? 280 LEU B CD2 1 
ATOM   6124 N N   . GLU B 1 281 ? 114.144 109.177 68.641  1.00 137.98 ? 281 GLU B N   1 
ATOM   6125 C CA  . GLU B 1 281 ? 113.986 109.277 70.088  1.00 137.98 ? 281 GLU B CA  1 
ATOM   6126 C C   . GLU B 1 281 ? 115.236 108.715 70.754  1.00 137.98 ? 281 GLU B C   1 
ATOM   6127 O O   . GLU B 1 281 ? 115.493 107.509 70.696  1.00 137.98 ? 281 GLU B O   1 
ATOM   6128 C CB  . GLU B 1 281 ? 112.732 108.548 70.557  1.00 137.98 ? 281 GLU B CB  1 
ATOM   6129 C CG  . GLU B 1 281 ? 112.497 108.665 72.055  1.00 137.98 ? 281 GLU B CG  1 
ATOM   6130 C CD  . GLU B 1 281 ? 111.035 108.562 72.435  1.00 137.98 ? 281 GLU B CD  1 
ATOM   6131 O OE1 . GLU B 1 281 ? 110.317 107.740 71.831  1.00 137.98 ? 281 GLU B OE1 1 
ATOM   6132 O OE2 . GLU B 1 281 ? 110.602 109.310 73.338  1.00 137.98 ? 281 GLU B OE2 1 
ATOM   6133 N N   . VAL B 1 282 ? 116.015 109.592 71.384  1.00 134.84 ? 282 VAL B N   1 
ATOM   6134 C CA  . VAL B 1 282 ? 117.279 109.236 72.016  1.00 134.84 ? 282 VAL B CA  1 
ATOM   6135 C C   . VAL B 1 282 ? 117.208 109.633 73.483  1.00 134.84 ? 282 VAL B C   1 
ATOM   6136 O O   . VAL B 1 282 ? 116.641 110.677 73.822  1.00 134.84 ? 282 VAL B O   1 
ATOM   6137 C CB  . VAL B 1 282 ? 118.474 109.920 71.316  1.00 134.84 ? 282 VAL B CB  1 
ATOM   6138 C CG1 . VAL B 1 282 ? 119.793 109.415 71.882  1.00 134.84 ? 282 VAL B CG1 1 
ATOM   6139 C CG2 . VAL B 1 282 ? 118.416 109.692 69.812  1.00 134.84 ? 282 VAL B CG2 1 
ATOM   6140 N N   . THR B 1 283 ? 117.773 108.788 74.353  1.00 131.35 ? 283 THR B N   1 
ATOM   6141 C CA  . THR B 1 283 ? 117.703 109.043 75.789  1.00 131.35 ? 283 THR B CA  1 
ATOM   6142 C C   . THR B 1 283 ? 118.412 110.342 76.171  1.00 131.35 ? 283 THR B C   1 
ATOM   6143 O O   . THR B 1 283 ? 117.898 111.115 76.987  1.00 131.35 ? 283 THR B O   1 
ATOM   6144 C CB  . THR B 1 283 ? 118.262 107.845 76.567  1.00 131.35 ? 283 THR B CB  1 
ATOM   6145 O OG1 . THR B 1 283 ? 118.174 108.094 77.976  1.00 131.35 ? 283 THR B OG1 1 
ATOM   6146 C CG2 . THR B 1 283 ? 119.705 107.517 76.175  1.00 131.35 ? 283 THR B CG2 1 
ATOM   6147 N N   . GLY B 1 284 ? 119.583 110.605 75.592  1.00 138.68 ? 284 GLY B N   1 
ATOM   6148 C CA  . GLY B 1 284 ? 120.301 111.837 75.863  1.00 138.68 ? 284 GLY B CA  1 
ATOM   6149 C C   . GLY B 1 284 ? 120.894 111.933 77.254  1.00 138.68 ? 284 GLY B C   1 
ATOM   6150 O O   . GLY B 1 284 ? 120.501 111.195 78.163  1.00 138.68 ? 284 GLY B O   1 
ATOM   6151 N N   . LYS B 1 285 ? 121.854 112.838 77.433  1.00 140.99 ? 285 LYS B N   1 
ATOM   6152 C CA  . LYS B 1 285 ? 122.465 113.098 78.737  1.00 140.99 ? 285 LYS B CA  1 
ATOM   6153 C C   . LYS B 1 285 ? 122.593 114.607 78.928  1.00 140.99 ? 285 LYS B C   1 
ATOM   6154 O O   . LYS B 1 285 ? 123.536 115.224 78.426  1.00 140.99 ? 285 LYS B O   1 
ATOM   6155 C CB  . LYS B 1 285 ? 123.821 112.411 78.862  1.00 140.99 ? 285 LYS B CB  1 
ATOM   6156 C CG  . LYS B 1 285 ? 124.437 112.532 80.248  1.00 140.99 ? 285 LYS B CG  1 
ATOM   6157 C CD  . LYS B 1 285 ? 123.489 112.037 81.328  1.00 140.99 ? 285 LYS B CD  1 
ATOM   6158 C CE  . LYS B 1 285 ? 124.249 111.574 82.559  1.00 140.99 ? 285 LYS B CE  1 
ATOM   6159 N NZ  . LYS B 1 285 ? 123.506 110.525 83.306  1.00 140.99 ? 285 LYS B NZ  1 
ATOM   6160 N N   . THR B 1 286 ? 121.645 115.192 79.660  1.00 144.99 ? 286 THR B N   1 
ATOM   6161 C CA  . THR B 1 286 ? 121.707 116.606 80.011  1.00 144.99 ? 286 THR B CA  1 
ATOM   6162 C C   . THR B 1 286 ? 120.894 116.835 81.277  1.00 144.99 ? 286 THR B C   1 
ATOM   6163 O O   . THR B 1 286 ? 119.764 116.347 81.394  1.00 144.99 ? 286 THR B O   1 
ATOM   6164 C CB  . THR B 1 286 ? 121.213 117.497 78.856  1.00 144.99 ? 286 THR B CB  1 
ATOM   6165 O OG1 . THR B 1 286 ? 121.270 118.875 79.249  1.00 144.99 ? 286 THR B OG1 1 
ATOM   6166 C CG2 . THR B 1 286 ? 119.797 117.134 78.411  1.00 144.99 ? 286 THR B CG2 1 
ATOM   6167 N N   . LYS B 1 287 ? 121.489 117.536 82.241  1.00 146.78 ? 287 LYS B N   1 
ATOM   6168 C CA  . LYS B 1 287 ? 120.832 117.846 83.503  1.00 146.78 ? 287 LYS B CA  1 
ATOM   6169 C C   . LYS B 1 287 ? 120.277 119.262 83.551  1.00 146.78 ? 287 LYS B C   1 
ATOM   6170 O O   . LYS B 1 287 ? 119.761 119.675 84.594  1.00 146.78 ? 287 LYS B O   1 
ATOM   6171 C CB  . LYS B 1 287 ? 121.800 117.631 84.673  1.00 146.78 ? 287 LYS B CB  1 
ATOM   6172 C CG  . LYS B 1 287 ? 122.924 116.639 84.396  1.00 146.78 ? 287 LYS B CG  1 
ATOM   6173 C CD  . LYS B 1 287 ? 122.423 115.198 84.347  1.00 146.78 ? 287 LYS B CD  1 
ATOM   6174 C CE  . LYS B 1 287 ? 121.483 114.884 85.501  1.00 146.78 ? 287 LYS B CE  1 
ATOM   6175 N NZ  . LYS B 1 287 ? 120.903 113.517 85.392  1.00 146.78 ? 287 LYS B NZ  1 
ATOM   6176 N N   . ALA B 1 288 ? 120.392 120.023 82.463  1.00 148.61 ? 288 ALA B N   1 
ATOM   6177 C CA  . ALA B 1 288 ? 119.874 121.387 82.455  1.00 148.61 ? 288 ALA B CA  1 
ATOM   6178 C C   . ALA B 1 288 ? 118.355 121.410 82.332  1.00 148.61 ? 288 ALA B C   1 
ATOM   6179 O O   . ALA B 1 288 ? 117.686 122.223 82.979  1.00 148.61 ? 288 ALA B O   1 
ATOM   6180 C CB  . ALA B 1 288 ? 120.516 122.185 81.321  1.00 148.61 ? 288 ALA B CB  1 
ATOM   6181 N N   . TYR B 1 289 ? 117.796 120.524 81.510  1.00 140.41 ? 289 TYR B N   1 
ATOM   6182 C CA  . TYR B 1 289 ? 116.381 120.575 81.138  1.00 140.41 ? 289 TYR B CA  1 
ATOM   6183 C C   . TYR B 1 289 ? 115.555 119.895 82.228  1.00 140.41 ? 289 TYR B C   1 
ATOM   6184 O O   . TYR B 1 289 ? 115.175 118.725 82.137  1.00 140.41 ? 289 TYR B O   1 
ATOM   6185 C CB  . TYR B 1 289 ? 116.173 119.922 79.778  1.00 140.41 ? 289 TYR B CB  1 
ATOM   6186 C CG  . TYR B 1 289 ? 116.654 120.752 78.601  1.00 140.41 ? 289 TYR B CG  1 
ATOM   6187 C CD1 . TYR B 1 289 ? 117.399 121.911 78.792  1.00 140.41 ? 289 TYR B CD1 1 
ATOM   6188 C CD2 . TYR B 1 289 ? 116.394 120.355 77.297  1.00 140.41 ? 289 TYR B CD2 1 
ATOM   6189 C CE1 . TYR B 1 289 ? 117.846 122.662 77.721  1.00 140.41 ? 289 TYR B CE1 1 
ATOM   6190 C CE2 . TYR B 1 289 ? 116.844 121.098 76.221  1.00 140.41 ? 289 TYR B CE2 1 
ATOM   6191 C CZ  . TYR B 1 289 ? 117.565 122.250 76.439  1.00 140.41 ? 289 TYR B CZ  1 
ATOM   6192 O OH  . TYR B 1 289 ? 118.010 122.990 75.368  1.00 140.41 ? 289 TYR B OH  1 
ATOM   6193 N N   . VAL B 1 290 ? 115.270 120.656 83.287  1.00 142.08 ? 290 VAL B N   1 
ATOM   6194 C CA  . VAL B 1 290 ? 114.545 120.164 84.454  1.00 142.08 ? 290 VAL B CA  1 
ATOM   6195 C C   . VAL B 1 290 ? 113.407 121.125 84.769  1.00 142.08 ? 290 VAL B C   1 
ATOM   6196 O O   . VAL B 1 290 ? 113.565 122.345 84.665  1.00 142.08 ? 290 VAL B O   1 
ATOM   6197 C CB  . VAL B 1 290 ? 115.475 119.998 85.679  1.00 142.08 ? 290 VAL B CB  1 
ATOM   6198 C CG1 . VAL B 1 290 ? 114.727 119.373 86.849  1.00 142.08 ? 290 VAL B CG1 1 
ATOM   6199 C CG2 . VAL B 1 290 ? 116.680 119.148 85.329  1.00 142.08 ? 290 VAL B CG2 1 
ATOM   6200 N N   . SER B 1 291 ? 112.259 120.569 85.154  1.00 149.69 ? 291 SER B N   1 
ATOM   6201 C CA  . SER B 1 291 ? 111.078 121.346 85.493  1.00 149.69 ? 291 SER B CA  1 
ATOM   6202 C C   . SER B 1 291 ? 111.194 121.938 86.893  1.00 149.69 ? 291 SER B C   1 
ATOM   6203 O O   . SER B 1 291 ? 111.981 121.483 87.725  1.00 149.69 ? 291 SER B O   1 
ATOM   6204 C CB  . SER B 1 291 ? 109.826 120.476 85.415  1.00 149.69 ? 291 SER B CB  1 
ATOM   6205 O OG  . SER B 1 291 ? 109.755 119.587 86.516  1.00 149.69 ? 291 SER B OG  1 
ATOM   6206 N N   . LYS B 1 292 ? 110.378 122.960 87.153  1.00 155.42 ? 292 LYS B N   1 
ATOM   6207 C CA  . LYS B 1 292 ? 110.311 123.570 88.475  1.00 155.42 ? 292 LYS B CA  1 
ATOM   6208 C C   . LYS B 1 292 ? 108.890 124.039 88.760  1.00 155.42 ? 292 LYS B C   1 
ATOM   6209 O O   . LYS B 1 292 ? 108.155 124.438 87.852  1.00 155.42 ? 292 LYS B O   1 
ATOM   6210 C CB  . LYS B 1 292 ? 111.284 124.749 88.616  1.00 155.42 ? 292 LYS B CB  1 
ATOM   6211 C CG  . LYS B 1 292 ? 112.717 124.349 88.936  1.00 155.42 ? 292 LYS B CG  1 
ATOM   6212 C CD  . LYS B 1 292 ? 112.769 123.470 90.179  1.00 155.42 ? 292 LYS B CD  1 
ATOM   6213 C CE  . LYS B 1 292 ? 114.198 123.250 90.652  1.00 155.42 ? 292 LYS B CE  1 
ATOM   6214 N NZ  . LYS B 1 292 ? 114.849 124.524 91.061  1.00 155.42 ? 292 LYS B NZ  1 
ATOM   6215 N N   . GLN B 1 293 ? 108.525 124.001 90.040  1.00 166.79 ? 293 GLN B N   1 
ATOM   6216 C CA  . GLN B 1 293 ? 107.233 124.472 90.524  1.00 166.79 ? 293 GLN B CA  1 
ATOM   6217 C C   . GLN B 1 293 ? 107.429 125.755 91.319  1.00 166.79 ? 293 GLN B C   1 
ATOM   6218 O O   . GLN B 1 293 ? 108.310 125.826 92.183  1.00 166.79 ? 293 GLN B O   1 
ATOM   6219 C CB  . GLN B 1 293 ? 106.548 123.413 91.390  1.00 166.79 ? 293 GLN B CB  1 
ATOM   6220 C CG  . GLN B 1 293 ? 107.015 121.995 91.128  1.00 166.79 ? 293 GLN B CG  1 
ATOM   6221 C CD  . GLN B 1 293 ? 106.476 121.012 92.148  1.00 166.79 ? 293 GLN B CD  1 
ATOM   6222 O OE1 . GLN B 1 293 ? 105.298 121.049 92.499  1.00 166.79 ? 293 GLN B OE1 1 
ATOM   6223 N NE2 . GLN B 1 293 ? 107.341 120.127 92.630  1.00 166.79 ? 293 GLN B NE2 1 
ATOM   6224 N N   . VAL B 1 294 ? 106.614 126.764 91.021  1.00 170.71 ? 294 VAL B N   1 
ATOM   6225 C CA  . VAL B 1 294 ? 106.760 128.108 91.570  1.00 170.71 ? 294 VAL B CA  1 
ATOM   6226 C C   . VAL B 1 294 ? 105.376 128.664 91.878  1.00 170.71 ? 294 VAL B C   1 
ATOM   6227 O O   . VAL B 1 294 ? 104.456 128.537 91.063  1.00 170.71 ? 294 VAL B O   1 
ATOM   6228 C CB  . VAL B 1 294 ? 107.519 129.025 90.588  1.00 170.71 ? 294 VAL B CB  1 
ATOM   6229 C CG1 . VAL B 1 294 ? 107.301 130.495 90.917  1.00 170.71 ? 294 VAL B CG1 1 
ATOM   6230 C CG2 . VAL B 1 294 ? 109.000 128.683 90.589  1.00 170.71 ? 294 VAL B CG2 1 
ATOM   6231 N N   . VAL B 1 295 ? 105.223 129.271 93.058  1.00 173.43 ? 295 VAL B N   1 
ATOM   6232 C CA  . VAL B 1 295 ? 103.978 129.940 93.420  1.00 173.43 ? 295 VAL B CA  1 
ATOM   6233 C C   . VAL B 1 295 ? 103.980 131.349 92.835  1.00 173.43 ? 295 VAL B C   1 
ATOM   6234 O O   . VAL B 1 295 ? 105.003 132.042 92.844  1.00 173.43 ? 295 VAL B O   1 
ATOM   6235 C CB  . VAL B 1 295 ? 103.790 129.944 94.951  1.00 173.43 ? 295 VAL B CB  1 
ATOM   6236 C CG1 . VAL B 1 295 ? 105.060 130.383 95.656  1.00 173.43 ? 295 VAL B CG1 1 
ATOM   6237 C CG2 . VAL B 1 295 ? 102.607 130.814 95.368  1.00 173.43 ? 295 VAL B CG2 1 
ATOM   6238 N N   . LEU B 1 296 ? 102.831 131.773 92.315  1.00 180.45 ? 296 LEU B N   1 
ATOM   6239 C CA  . LEU B 1 296 ? 102.726 133.024 91.579  1.00 180.45 ? 296 LEU B CA  1 
ATOM   6240 C C   . LEU B 1 296 ? 102.471 134.198 92.522  1.00 180.45 ? 296 LEU B C   1 
ATOM   6241 O O   . LEU B 1 296 ? 102.211 134.033 93.715  1.00 180.45 ? 296 LEU B O   1 
ATOM   6242 C CB  . LEU B 1 296 ? 101.611 132.937 90.536  1.00 180.45 ? 296 LEU B CB  1 
ATOM   6243 C CG  . LEU B 1 296 ? 101.852 132.042 89.318  1.00 180.45 ? 296 LEU B CG  1 
ATOM   6244 C CD1 . LEU B 1 296 ? 101.106 132.576 88.104  1.00 180.45 ? 296 LEU B CD1 1 
ATOM   6245 C CD2 . LEU B 1 296 ? 103.337 131.893 89.027  1.00 180.45 ? 296 LEU B CD2 1 
ATOM   6246 N N   . LYS B 1 297 ? 102.564 135.402 91.965  1.00 185.06 ? 297 LYS B N   1 
ATOM   6247 C CA  . LYS B 1 297 ? 102.248 136.620 92.692  1.00 185.06 ? 297 LYS B CA  1 
ATOM   6248 C C   . LYS B 1 297 ? 100.766 136.959 92.540  1.00 185.06 ? 297 LYS B C   1 
ATOM   6249 O O   . LYS B 1 297 ? 100.041 136.361 91.742  1.00 185.06 ? 297 LYS B O   1 
ATOM   6250 C CB  . LYS B 1 297 ? 103.116 137.781 92.205  1.00 185.06 ? 297 LYS B CB  1 
ATOM   6251 C CG  . LYS B 1 297 ? 102.917 138.142 90.742  1.00 185.06 ? 297 LYS B CG  1 
ATOM   6252 C CD  . LYS B 1 297 ? 103.741 139.361 90.358  1.00 185.06 ? 297 LYS B CD  1 
ATOM   6253 C CE  . LYS B 1 297 ? 103.593 139.692 88.882  1.00 185.06 ? 297 LYS B CE  1 
ATOM   6254 N NZ  . LYS B 1 297 ? 103.970 138.543 88.013  1.00 185.06 ? 297 LYS B NZ  1 
ATOM   6255 N N   . LYS B 1 298 ? 100.318 137.938 93.332  1.00 190.75 ? 298 LYS B N   1 
ATOM   6256 C CA  . LYS B 1 298 ? 98.921  138.358 93.279  1.00 190.75 ? 298 LYS B CA  1 
ATOM   6257 C C   . LYS B 1 298 ? 98.581  138.984 91.931  1.00 190.75 ? 298 LYS B C   1 
ATOM   6258 O O   . LYS B 1 298 ? 97.491  138.760 91.390  1.00 190.75 ? 298 LYS B O   1 
ATOM   6259 C CB  . LYS B 1 298 ? 98.625  139.328 94.426  1.00 190.75 ? 298 LYS B CB  1 
ATOM   6260 C CG  . LYS B 1 298 ? 97.508  140.330 94.157  1.00 190.75 ? 298 LYS B CG  1 
ATOM   6261 C CD  . LYS B 1 298 ? 96.134  139.679 94.253  1.00 190.75 ? 298 LYS B CD  1 
ATOM   6262 C CE  . LYS B 1 298 ? 95.936  138.991 95.593  1.00 190.75 ? 298 LYS B CE  1 
ATOM   6263 N NZ  . LYS B 1 298 ? 94.620  138.300 95.669  1.00 190.75 ? 298 LYS B NZ  1 
ATOM   6264 N N   . ASN B 1 299 ? 99.506  139.767 91.368  1.00 188.64 ? 299 ASN B N   1 
ATOM   6265 C CA  . ASN B 1 299 ? 99.256  140.404 90.077  1.00 188.64 ? 299 ASN B CA  1 
ATOM   6266 C C   . ASN B 1 299 ? 99.112  139.379 88.958  1.00 188.64 ? 299 ASN B C   1 
ATOM   6267 O O   . ASN B 1 299 ? 98.362  139.619 88.004  1.00 188.64 ? 299 ASN B O   1 
ATOM   6268 C CB  . ASN B 1 299 ? 100.377 141.391 89.753  1.00 188.64 ? 299 ASN B CB  1 
ATOM   6269 C CG  . ASN B 1 299 ? 100.826 142.182 90.968  1.00 188.64 ? 299 ASN B CG  1 
ATOM   6270 O OD1 . ASN B 1 299 ? 100.094 142.298 91.950  1.00 188.64 ? 299 ASN B OD1 1 
ATOM   6271 N ND2 . ASN B 1 299 ? 102.034 142.730 90.906  1.00 188.64 ? 299 ASN B ND2 1 
ATOM   6272 N N   . PHE B 1 300 ? 99.829  138.258 89.063  1.00 189.15 ? 300 PHE B N   1 
ATOM   6273 C CA  . PHE B 1 300 ? 99.765  137.092 88.165  1.00 189.15 ? 300 PHE B CA  1 
ATOM   6274 C C   . PHE B 1 300 ? 99.587  137.501 86.693  1.00 189.15 ? 300 PHE B C   1 
ATOM   6275 O O   . PHE B 1 300 ? 98.633  137.144 86.004  1.00 189.15 ? 300 PHE B O   1 
ATOM   6276 C CB  . PHE B 1 300 ? 98.725  136.066 88.680  1.00 189.15 ? 300 PHE B CB  1 
ATOM   6277 C CG  . PHE B 1 300 ? 97.292  136.297 88.244  1.00 189.15 ? 300 PHE B CG  1 
ATOM   6278 C CD1 . PHE B 1 300 ? 96.546  137.350 88.740  1.00 189.15 ? 300 PHE B CD1 1 
ATOM   6279 C CD2 . PHE B 1 300 ? 96.678  135.410 87.368  1.00 189.15 ? 300 PHE B CD2 1 
ATOM   6280 C CE1 . PHE B 1 300 ? 95.238  137.547 88.338  1.00 189.15 ? 300 PHE B CE1 1 
ATOM   6281 C CE2 . PHE B 1 300 ? 95.376  135.602 86.963  1.00 189.15 ? 300 PHE B CE2 1 
ATOM   6282 C CZ  . PHE B 1 300 ? 94.651  136.667 87.454  1.00 189.15 ? 300 PHE B CZ  1 
ATOM   6283 N N   . SER B 1 301 ? 100.560 138.279 86.221  1.00 182.98 ? 301 SER B N   1 
ATOM   6284 C CA  . SER B 1 301 ? 100.512 138.815 84.865  1.00 182.98 ? 301 SER B CA  1 
ATOM   6285 C C   . SER B 1 301 ? 100.394 137.697 83.835  1.00 182.98 ? 301 SER B C   1 
ATOM   6286 O O   . SER B 1 301 ? 101.048 136.658 83.939  1.00 182.98 ? 301 SER B O   1 
ATOM   6287 C CB  . SER B 1 301 ? 101.757 139.657 84.587  1.00 182.98 ? 301 SER B CB  1 
ATOM   6288 O OG  . SER B 1 301 ? 101.771 140.118 83.246  1.00 182.98 ? 301 SER B OG  1 
ATOM   6289 N N   . ALA B 1 302 ? 99.514  137.904 82.855  1.00 178.42 ? 302 ALA B N   1 
ATOM   6290 C CA  . ALA B 1 302 ? 99.319  136.952 81.772  1.00 178.42 ? 302 ALA B CA  1 
ATOM   6291 C C   . ALA B 1 302 ? 100.090 137.320 80.514  1.00 178.42 ? 302 ALA B C   1 
ATOM   6292 O O   . ALA B 1 302 ? 100.317 136.450 79.663  1.00 178.42 ? 302 ALA B O   1 
ATOM   6293 C CB  . ALA B 1 302 ? 97.828  136.829 81.436  1.00 178.42 ? 302 ALA B CB  1 
ATOM   6294 N N   . ASP B 1 303 ? 100.490 138.586 80.376  1.00 176.78 ? 303 ASP B N   1 
ATOM   6295 C CA  . ASP B 1 303 ? 101.350 138.973 79.265  1.00 176.78 ? 303 ASP B CA  1 
ATOM   6296 C C   . ASP B 1 303 ? 102.681 138.241 79.330  1.00 176.78 ? 303 ASP B C   1 
ATOM   6297 O O   . ASP B 1 303 ? 103.216 137.815 78.301  1.00 176.78 ? 303 ASP B O   1 
ATOM   6298 C CB  . ASP B 1 303 ? 101.563 140.487 79.267  1.00 176.78 ? 303 ASP B CB  1 
ATOM   6299 C CG  . ASP B 1 303 ? 100.261 141.258 79.153  1.00 176.78 ? 303 ASP B CG  1 
ATOM   6300 O OD1 . ASP B 1 303 ? 99.191  140.616 79.089  1.00 176.78 ? 303 ASP B OD1 1 
ATOM   6301 O OD2 . ASP B 1 303 ? 100.309 142.505 79.128  1.00 176.78 ? 303 ASP B OD2 1 
ATOM   6302 N N   . VAL B 1 304 ? 103.228 138.072 80.538  1.00 174.63 ? 304 VAL B N   1 
ATOM   6303 C CA  . VAL B 1 304 ? 104.444 137.282 80.684  1.00 174.63 ? 304 VAL B CA  1 
ATOM   6304 C C   . VAL B 1 304 ? 104.163 135.814 80.379  1.00 174.63 ? 304 VAL B C   1 
ATOM   6305 O O   . VAL B 1 304 ? 105.048 135.097 79.904  1.00 174.63 ? 304 VAL B O   1 
ATOM   6306 C CB  . VAL B 1 304 ? 105.056 137.483 82.088  1.00 174.63 ? 304 VAL B CB  1 
ATOM   6307 C CG1 . VAL B 1 304 ? 104.054 137.154 83.172  1.00 174.63 ? 304 VAL B CG1 1 
ATOM   6308 C CG2 . VAL B 1 304 ? 106.342 136.678 82.260  1.00 174.63 ? 304 VAL B CG2 1 
ATOM   6309 N N   . LEU B 1 305 ? 102.934 135.343 80.613  1.00 175.28 ? 305 LEU B N   1 
ATOM   6310 C CA  . LEU B 1 305 ? 102.583 133.981 80.215  1.00 175.28 ? 305 LEU B CA  1 
ATOM   6311 C C   . LEU B 1 305 ? 102.617 133.820 78.697  1.00 175.28 ? 305 LEU B C   1 
ATOM   6312 O O   . LEU B 1 305 ? 103.153 132.829 78.183  1.00 175.28 ? 305 LEU B O   1 
ATOM   6313 C CB  . LEU B 1 305 ? 101.208 133.601 80.765  1.00 175.28 ? 305 LEU B CB  1 
ATOM   6314 C CG  . LEU B 1 305 ? 101.188 132.701 82.002  1.00 175.28 ? 305 LEU B CG  1 
ATOM   6315 C CD1 . LEU B 1 305 ? 101.585 133.481 83.245  1.00 175.28 ? 305 LEU B CD1 1 
ATOM   6316 C CD2 . LEU B 1 305 ? 99.818  132.064 82.179  1.00 175.28 ? 305 LEU B CD2 1 
ATOM   6317 N N   . LYS B 1 306 ? 102.053 134.784 77.962  1.00 172.84 ? 306 LYS B N   1 
ATOM   6318 C CA  . LYS B 1 306 ? 102.154 134.746 76.502  1.00 172.84 ? 306 LYS B CA  1 
ATOM   6319 C C   . LYS B 1 306 ? 103.604 134.848 76.040  1.00 172.84 ? 306 LYS B C   1 
ATOM   6320 O O   . LYS B 1 306 ? 104.021 134.145 75.110  1.00 172.84 ? 306 LYS B O   1 
ATOM   6321 C CB  . LYS B 1 306 ? 101.318 135.860 75.869  1.00 172.84 ? 306 LYS B CB  1 
ATOM   6322 C CG  . LYS B 1 306 ? 99.973  135.407 75.314  1.00 172.84 ? 306 LYS B CG  1 
ATOM   6323 C CD  . LYS B 1 306 ? 98.976  135.025 76.388  1.00 172.84 ? 306 LYS B CD  1 
ATOM   6324 C CE  . LYS B 1 306 ? 98.420  136.253 77.082  1.00 172.84 ? 306 LYS B CE  1 
ATOM   6325 N NZ  . LYS B 1 306 ? 97.613  135.885 78.274  1.00 172.84 ? 306 LYS B NZ  1 
ATOM   6326 N N   . ASN B 1 307 ? 104.387 135.723 76.677  1.00 171.97 ? 307 ASN B N   1 
ATOM   6327 C CA  . ASN B 1 307 ? 105.788 135.863 76.295  1.00 171.97 ? 307 ASN B CA  1 
ATOM   6328 C C   . ASN B 1 307 ? 106.586 134.604 76.605  1.00 171.97 ? 307 ASN B C   1 
ATOM   6329 O O   . ASN B 1 307 ? 107.515 134.272 75.870  1.00 171.97 ? 307 ASN B O   1 
ATOM   6330 C CB  . ASN B 1 307 ? 106.405 137.077 76.987  1.00 171.97 ? 307 ASN B CB  1 
ATOM   6331 C CG  . ASN B 1 307 ? 105.694 138.369 76.636  1.00 171.97 ? 307 ASN B CG  1 
ATOM   6332 O OD1 . ASN B 1 307 ? 104.793 138.386 75.799  1.00 171.97 ? 307 ASN B OD1 1 
ATOM   6333 N ND2 . ASN B 1 307 ? 106.096 139.460 77.278  1.00 171.97 ? 307 ASN B ND2 1 
ATOM   6334 N N   . ALA B 1 308 ? 106.211 133.863 77.649  1.00 162.45 ? 308 ALA B N   1 
ATOM   6335 C CA  . ALA B 1 308 ? 106.885 132.606 77.953  1.00 162.45 ? 308 ALA B CA  1 
ATOM   6336 C C   . ALA B 1 308 ? 106.459 131.496 77.005  1.00 162.45 ? 308 ALA B C   1 
ATOM   6337 O O   . ALA B 1 308 ? 107.266 130.615 76.684  1.00 162.45 ? 308 ALA B O   1 
ATOM   6338 C CB  . ALA B 1 308 ? 106.613 132.195 79.401  1.00 162.45 ? 308 ALA B CB  1 
ATOM   6339 N N   . GLN B 1 309 ? 105.201 131.515 76.558  1.00 160.76 ? 309 GLN B N   1 
ATOM   6340 C CA  . GLN B 1 309 ? 104.780 130.594 75.506  1.00 160.76 ? 309 GLN B CA  1 
ATOM   6341 C C   . GLN B 1 309 ? 105.568 130.843 74.225  1.00 160.76 ? 309 GLN B C   1 
ATOM   6342 O O   . GLN B 1 309 ? 105.997 129.897 73.556  1.00 160.76 ? 309 GLN B O   1 
ATOM   6343 C CB  . GLN B 1 309 ? 103.269 130.723 75.272  1.00 160.76 ? 309 GLN B CB  1 
ATOM   6344 C CG  . GLN B 1 309 ? 102.747 130.224 73.922  1.00 160.76 ? 309 GLN B CG  1 
ATOM   6345 C CD  . GLN B 1 309 ? 102.814 131.275 72.826  1.00 160.76 ? 309 GLN B CD  1 
ATOM   6346 O OE1 . GLN B 1 309 ? 102.488 132.441 73.048  1.00 160.76 ? 309 GLN B OE1 1 
ATOM   6347 N NE2 . GLN B 1 309 ? 103.249 130.866 71.640  1.00 160.76 ? 309 GLN B NE2 1 
ATOM   6348 N N   . ASP B 1 310 ? 105.770 132.115 73.873  1.00 157.35 ? 310 ASP B N   1 
ATOM   6349 C CA  . ASP B 1 310 ? 106.638 132.441 72.744  1.00 157.35 ? 310 ASP B CA  1 
ATOM   6350 C C   . ASP B 1 310 ? 108.090 132.074 73.028  1.00 157.35 ? 310 ASP B C   1 
ATOM   6351 O O   . ASP B 1 310 ? 108.834 131.713 72.107  1.00 157.35 ? 310 ASP B O   1 
ATOM   6352 C CB  . ASP B 1 310 ? 106.535 133.929 72.409  1.00 157.35 ? 310 ASP B CB  1 
ATOM   6353 C CG  . ASP B 1 310 ? 105.572 134.206 71.273  1.00 157.35 ? 310 ASP B CG  1 
ATOM   6354 O OD1 . ASP B 1 310 ? 105.159 133.243 70.594  1.00 157.35 ? 310 ASP B OD1 1 
ATOM   6355 O OD2 . ASP B 1 310 ? 105.234 135.389 71.057  1.00 157.35 ? 310 ASP B OD2 1 
ATOM   6356 N N   . LYS B 1 311 ? 108.504 132.164 74.291  1.00 154.49 ? 311 LYS B N   1 
ATOM   6357 C CA  . LYS B 1 311 ? 109.903 131.981 74.658  1.00 154.49 ? 311 LYS B CA  1 
ATOM   6358 C C   . LYS B 1 311 ? 110.310 130.515 74.611  1.00 154.49 ? 311 LYS B C   1 
ATOM   6359 O O   . LYS B 1 311 ? 111.431 130.190 74.200  1.00 154.49 ? 311 LYS B O   1 
ATOM   6360 C CB  . LYS B 1 311 ? 110.131 132.587 76.043  1.00 154.49 ? 311 LYS B CB  1 
ATOM   6361 C CG  . LYS B 1 311 ? 111.111 131.865 76.937  1.00 154.49 ? 311 LYS B CG  1 
ATOM   6362 C CD  . LYS B 1 311 ? 111.550 132.790 78.059  1.00 154.49 ? 311 LYS B CD  1 
ATOM   6363 C CE  . LYS B 1 311 ? 112.357 132.053 79.101  1.00 154.49 ? 311 LYS B CE  1 
ATOM   6364 N NZ  . LYS B 1 311 ? 112.938 132.973 80.118  1.00 154.49 ? 311 LYS B NZ  1 
ATOM   6365 N N   . GLY B 1 312 ? 109.419 129.616 75.013  1.00 146.78 ? 312 GLY B N   1 
ATOM   6366 C CA  . GLY B 1 312 ? 109.737 128.203 74.983  1.00 146.78 ? 312 GLY B CA  1 
ATOM   6367 C C   . GLY B 1 312 ? 109.567 127.492 76.309  1.00 146.78 ? 312 GLY B C   1 
ATOM   6368 O O   . GLY B 1 312 ? 110.204 126.464 76.556  1.00 146.78 ? 312 GLY B O   1 
ATOM   6369 N N   . VAL B 1 313 ? 108.707 128.027 77.170  1.00 148.27 ? 313 VAL B N   1 
ATOM   6370 C CA  . VAL B 1 313 ? 108.419 127.435 78.470  1.00 148.27 ? 313 VAL B CA  1 
ATOM   6371 C C   . VAL B 1 313 ? 106.954 127.021 78.481  1.00 148.27 ? 313 VAL B C   1 
ATOM   6372 O O   . VAL B 1 313 ? 106.064 127.865 78.321  1.00 148.27 ? 313 VAL B O   1 
ATOM   6373 C CB  . VAL B 1 313 ? 108.728 128.407 79.619  1.00 148.27 ? 313 VAL B CB  1 
ATOM   6374 C CG1 . VAL B 1 313 ? 108.088 127.930 80.905  1.00 148.27 ? 313 VAL B CG1 1 
ATOM   6375 C CG2 . VAL B 1 313 ? 110.232 128.563 79.791  1.00 148.27 ? 313 VAL B CG2 1 
ATOM   6376 N N   . LEU B 1 314 ? 106.707 125.725 78.658  1.00 147.47 ? 314 LEU B N   1 
ATOM   6377 C CA  . LEU B 1 314 ? 105.342 125.224 78.712  1.00 147.47 ? 314 LEU B CA  1 
ATOM   6378 C C   . LEU B 1 314 ? 104.739 125.519 80.080  1.00 147.47 ? 314 LEU B C   1 
ATOM   6379 O O   . LEU B 1 314 ? 105.413 125.414 81.109  1.00 147.47 ? 314 LEU B O   1 
ATOM   6380 C CB  . LEU B 1 314 ? 105.322 123.718 78.425  1.00 147.47 ? 314 LEU B CB  1 
ATOM   6381 C CG  . LEU B 1 314 ? 104.050 122.858 78.427  1.00 147.47 ? 314 LEU B CG  1 
ATOM   6382 C CD1 . LEU B 1 314 ? 102.813 123.610 77.952  1.00 147.47 ? 314 LEU B CD1 1 
ATOM   6383 C CD2 . LEU B 1 314 ? 104.257 121.598 77.603  1.00 147.47 ? 314 LEU B CD2 1 
ATOM   6384 N N   . VAL B 1 315 ? 103.464 125.888 80.087  1.00 160.19 ? 315 VAL B N   1 
ATOM   6385 C CA  . VAL B 1 315 ? 102.734 126.230 81.301  1.00 160.19 ? 315 VAL B CA  1 
ATOM   6386 C C   . VAL B 1 315 ? 101.955 125.000 81.749  1.00 160.19 ? 315 VAL B C   1 
ATOM   6387 O O   . VAL B 1 315 ? 101.316 124.330 80.927  1.00 160.19 ? 315 VAL B O   1 
ATOM   6388 C CB  . VAL B 1 315 ? 101.796 127.424 81.070  1.00 160.19 ? 315 VAL B CB  1 
ATOM   6389 C CG1 . VAL B 1 315 ? 102.567 128.731 81.162  1.00 160.19 ? 315 VAL B CG1 1 
ATOM   6390 C CG2 . VAL B 1 315 ? 101.119 127.306 79.711  1.00 160.19 ? 315 VAL B CG2 1 
ATOM   6391 N N   . ALA B 1 316 ? 102.009 124.683 83.043  1.00 160.57 ? 316 ALA B N   1 
ATOM   6392 C CA  . ALA B 1 316 ? 101.214 123.588 83.574  1.00 160.57 ? 316 ALA B CA  1 
ATOM   6393 C C   . ALA B 1 316 ? 100.846 123.905 85.013  1.00 160.57 ? 316 ALA B C   1 
ATOM   6394 O O   . ALA B 1 316 ? 101.462 124.757 85.656  1.00 160.57 ? 316 ALA B O   1 
ATOM   6395 C CB  . ALA B 1 316 ? 101.968 122.255 83.493  1.00 160.57 ? 316 ALA B CB  1 
ATOM   6396 N N   . THR B 1 317 ? 99.846  123.193 85.522  1.00 164.05 ? 317 THR B N   1 
ATOM   6397 C CA  . THR B 1 317 ? 99.464  123.352 86.915  1.00 164.05 ? 317 THR B CA  1 
ATOM   6398 C C   . THR B 1 317 ? 100.468 122.632 87.814  1.00 164.05 ? 317 THR B C   1 
ATOM   6399 O O   . THR B 1 317 ? 101.460 122.060 87.352  1.00 164.05 ? 317 THR B O   1 
ATOM   6400 C CB  . THR B 1 317 ? 98.045  122.833 87.141  1.00 164.05 ? 317 THR B CB  1 
ATOM   6401 O OG1 . THR B 1 317 ? 97.963  121.464 86.722  1.00 164.05 ? 317 THR B OG1 1 
ATOM   6402 C CG2 . THR B 1 317 ? 97.048  123.661 86.346  1.00 164.05 ? 317 THR B CG2 1 
ATOM   6403 N N   . LEU B 1 318 ? 100.213 122.670 89.124  1.00 164.11 ? 318 LEU B N   1 
ATOM   6404 C CA  . LEU B 1 318 ? 101.103 122.005 90.070  1.00 164.11 ? 318 LEU B CA  1 
ATOM   6405 C C   . LEU B 1 318 ? 101.123 120.497 89.854  1.00 164.11 ? 318 LEU B C   1 
ATOM   6406 O O   . LEU B 1 318 ? 102.176 119.860 89.979  1.00 164.11 ? 318 LEU B O   1 
ATOM   6407 C CB  . LEU B 1 318 ? 100.702 122.339 91.505  1.00 164.11 ? 318 LEU B CB  1 
ATOM   6408 C CG  . LEU B 1 318 ? 101.880 122.355 92.480  1.00 164.11 ? 318 LEU B CG  1 
ATOM   6409 C CD1 . LEU B 1 318 ? 102.757 123.574 92.258  1.00 164.11 ? 318 LEU B CD1 1 
ATOM   6410 C CD2 . LEU B 1 318 ? 101.385 122.301 93.918  1.00 164.11 ? 318 LEU B CD2 1 
ATOM   6411 N N   . ALA B 1 319 ? 99.967  119.906 89.546  1.00 161.01 ? 319 ALA B N   1 
ATOM   6412 C CA  . ALA B 1 319 ? 99.939  118.490 89.199  1.00 161.01 ? 319 ALA B CA  1 
ATOM   6413 C C   . ALA B 1 319 ? 100.726 118.225 87.923  1.00 161.01 ? 319 ALA B C   1 
ATOM   6414 O O   . ALA B 1 319 ? 101.447 117.225 87.822  1.00 161.01 ? 319 ALA B O   1 
ATOM   6415 C CB  . ALA B 1 319 ? 98.495  118.012 89.052  1.00 161.01 ? 319 ALA B CB  1 
ATOM   6416 N N   . GLY B 1 320 ? 100.606 119.114 86.939  1.00 156.35 ? 320 GLY B N   1 
ATOM   6417 C CA  . GLY B 1 320 ? 101.334 118.978 85.694  1.00 156.35 ? 320 GLY B CA  1 
ATOM   6418 C C   . GLY B 1 320 ? 100.464 118.490 84.555  1.00 156.35 ? 320 GLY B C   1 
ATOM   6419 O O   . GLY B 1 320 ? 100.179 117.293 84.459  1.00 156.35 ? 320 GLY B O   1 
ATOM   6420 N N   . ASP B 1 321 ? 100.039 119.408 83.690  1.00 157.05 ? 321 ASP B N   1 
ATOM   6421 C CA  . ASP B 1 321 ? 99.202  119.095 82.540  1.00 157.05 ? 321 ASP B CA  1 
ATOM   6422 C C   . ASP B 1 321 ? 99.119  120.324 81.649  1.00 157.05 ? 321 ASP B C   1 
ATOM   6423 O O   . ASP B 1 321 ? 99.169  121.458 82.134  1.00 157.05 ? 321 ASP B O   1 
ATOM   6424 C CB  . ASP B 1 321 ? 97.792  118.658 82.962  1.00 157.05 ? 321 ASP B CB  1 
ATOM   6425 C CG  . ASP B 1 321 ? 97.266  119.443 84.149  1.00 157.05 ? 321 ASP B CG  1 
ATOM   6426 O OD1 . ASP B 1 321 ? 97.808  120.532 84.436  1.00 157.05 ? 321 ASP B OD1 1 
ATOM   6427 O OD2 . ASP B 1 321 ? 96.307  118.972 84.794  1.00 157.05 ? 321 ASP B OD2 1 
ATOM   6428 N N   . VAL B 1 322 ? 98.991  120.089 80.343  1.00 165.22 ? 322 VAL B N   1 
ATOM   6429 C CA  . VAL B 1 322 ? 98.769  121.192 79.419  1.00 165.22 ? 322 VAL B CA  1 
ATOM   6430 C C   . VAL B 1 322 ? 97.387  121.783 79.669  1.00 165.22 ? 322 VAL B C   1 
ATOM   6431 O O   . VAL B 1 322 ? 96.431  121.069 80.008  1.00 165.22 ? 322 VAL B O   1 
ATOM   6432 C CB  . VAL B 1 322 ? 98.956  120.730 77.961  1.00 165.22 ? 322 VAL B CB  1 
ATOM   6433 C CG1 . VAL B 1 322 ? 97.737  119.975 77.443  1.00 165.22 ? 322 VAL B CG1 1 
ATOM   6434 C CG2 . VAL B 1 322 ? 99.275  121.918 77.064  1.00 165.22 ? 322 VAL B CG2 1 
ATOM   6435 N N   . MET B 1 323 ? 97.286  123.106 79.567  1.00 179.38 ? 323 MET B N   1 
ATOM   6436 C CA  . MET B 1 323 ? 96.058  123.817 79.882  1.00 179.38 ? 323 MET B CA  1 
ATOM   6437 C C   . MET B 1 323 ? 95.768  124.866 78.817  1.00 179.38 ? 323 MET B C   1 
ATOM   6438 O O   . MET B 1 323 ? 96.676  125.362 78.143  1.00 179.38 ? 323 MET B O   1 
ATOM   6439 C CB  . MET B 1 323 ? 96.132  124.444 81.287  1.00 179.38 ? 323 MET B CB  1 
ATOM   6440 C CG  . MET B 1 323 ? 97.490  125.025 81.652  1.00 179.38 ? 323 MET B CG  1 
ATOM   6441 S SD  . MET B 1 323 ? 97.823  126.638 80.933  1.00 179.38 ? 323 MET B SD  1 
ATOM   6442 C CE  . MET B 1 323 ? 96.626  127.641 81.806  1.00 179.38 ? 323 MET B CE  1 
ATOM   6443 N N   . ASP B 1 324 ? 94.484  125.185 78.670  1.00 191.67 ? 324 ASP B N   1 
ATOM   6444 C CA  . ASP B 1 324 ? 94.023  125.997 77.552  1.00 191.67 ? 324 ASP B CA  1 
ATOM   6445 C C   . ASP B 1 324 ? 94.558  127.424 77.663  1.00 191.67 ? 324 ASP B C   1 
ATOM   6446 O O   . ASP B 1 324 ? 94.603  127.988 78.762  1.00 191.67 ? 324 ASP B O   1 
ATOM   6447 C CB  . ASP B 1 324 ? 92.494  126.007 77.509  1.00 191.67 ? 324 ASP B CB  1 
ATOM   6448 C CG  . ASP B 1 324 ? 91.944  126.552 76.203  1.00 191.67 ? 324 ASP B CG  1 
ATOM   6449 O OD1 . ASP B 1 324 ? 92.068  127.770 75.957  1.00 191.67 ? 324 ASP B OD1 1 
ATOM   6450 O OD2 . ASP B 1 324 ? 91.379  125.758 75.422  1.00 191.67 ? 324 ASP B OD2 1 
ATOM   6451 N N   . PRO B 1 325 ? 94.971  128.032 76.544  1.00 193.48 ? 325 PRO B N   1 
ATOM   6452 C CA  . PRO B 1 325 ? 95.434  129.431 76.590  1.00 193.48 ? 325 PRO B CA  1 
ATOM   6453 C C   . PRO B 1 325 ? 94.381  130.408 77.081  1.00 193.48 ? 325 PRO B C   1 
ATOM   6454 O O   . PRO B 1 325 ? 94.734  131.435 77.674  1.00 193.48 ? 325 PRO B O   1 
ATOM   6455 C CB  . PRO B 1 325 ? 95.827  129.714 75.133  1.00 193.48 ? 325 PRO B CB  1 
ATOM   6456 C CG  . PRO B 1 325 ? 96.148  128.375 74.563  1.00 193.48 ? 325 PRO B CG  1 
ATOM   6457 C CD  . PRO B 1 325 ? 95.209  127.412 75.230  1.00 193.48 ? 325 PRO B CD  1 
ATOM   6458 N N   . ALA B 1 326 ? 93.095  130.124 76.855  1.00 194.25 ? 326 ALA B N   1 
ATOM   6459 C CA  . ALA B 1 326 ? 92.043  130.980 77.389  1.00 194.25 ? 326 ALA B CA  1 
ATOM   6460 C C   . ALA B 1 326 ? 92.031  130.986 78.911  1.00 194.25 ? 326 ALA B C   1 
ATOM   6461 O O   . ALA B 1 326 ? 91.488  131.920 79.512  1.00 194.25 ? 326 ALA B O   1 
ATOM   6462 C CB  . ALA B 1 326 ? 90.678  130.543 76.858  1.00 194.25 ? 326 ALA B CB  1 
ATOM   6463 N N   . GLN B 1 327 ? 92.618  129.970 79.546  1.00 195.31 ? 327 GLN B N   1 
ATOM   6464 C CA  . GLN B 1 327 ? 92.767  129.962 80.995  1.00 195.31 ? 327 GLN B CA  1 
ATOM   6465 C C   . GLN B 1 327 ? 93.812  130.955 81.485  1.00 195.31 ? 327 GLN B C   1 
ATOM   6466 O O   . GLN B 1 327 ? 93.903  131.172 82.698  1.00 195.31 ? 327 GLN B O   1 
ATOM   6467 C CB  . GLN B 1 327 ? 93.131  128.557 81.479  1.00 195.31 ? 327 GLN B CB  1 
ATOM   6468 C CG  . GLN B 1 327 ? 92.126  127.460 81.132  1.00 195.31 ? 327 GLN B CG  1 
ATOM   6469 C CD  . GLN B 1 327 ? 90.699  127.959 81.014  1.00 195.31 ? 327 GLN B CD  1 
ATOM   6470 O OE1 . GLN B 1 327 ? 90.099  127.906 79.940  1.00 195.31 ? 327 GLN B OE1 1 
ATOM   6471 N NE2 . GLN B 1 327 ? 90.133  128.415 82.129  1.00 195.31 ? 327 GLN B NE2 1 
ATOM   6472 N N   . PHE B 1 328 ? 94.606  131.547 80.586  1.00 193.43 ? 328 PHE B N   1 
ATOM   6473 C CA  . PHE B 1 328 ? 95.624  132.508 81.010  1.00 193.43 ? 328 PHE B CA  1 
ATOM   6474 C C   . PHE B 1 328 ? 94.994  133.730 81.670  1.00 193.43 ? 328 PHE B C   1 
ATOM   6475 O O   . PHE B 1 328 ? 95.486  134.213 82.696  1.00 193.43 ? 328 PHE B O   1 
ATOM   6476 C CB  . PHE B 1 328 ? 96.488  132.944 79.821  1.00 193.43 ? 328 PHE B CB  1 
ATOM   6477 C CG  . PHE B 1 328 ? 97.313  131.838 79.202  1.00 193.43 ? 328 PHE B CG  1 
ATOM   6478 C CD1 . PHE B 1 328 ? 97.383  130.577 79.771  1.00 193.43 ? 328 PHE B CD1 1 
ATOM   6479 C CD2 . PHE B 1 328 ? 98.016  132.074 78.032  1.00 193.43 ? 328 PHE B CD2 1 
ATOM   6480 C CE1 . PHE B 1 328 ? 98.140  129.580 79.186  1.00 193.43 ? 328 PHE B CE1 1 
ATOM   6481 C CE2 . PHE B 1 328 ? 98.774  131.079 77.445  1.00 193.43 ? 328 PHE B CE2 1 
ATOM   6482 C CZ  . PHE B 1 328 ? 98.835  129.831 78.022  1.00 193.43 ? 328 PHE B CZ  1 
ATOM   6483 N N   . SER B 1 329 ? 93.909  134.249 81.090  1.00 195.11 ? 329 SER B N   1 
ATOM   6484 C CA  . SER B 1 329 ? 93.309  135.474 81.609  1.00 195.11 ? 329 SER B CA  1 
ATOM   6485 C C   . SER B 1 329 ? 92.571  135.228 82.920  1.00 195.11 ? 329 SER B C   1 
ATOM   6486 O O   . SER B 1 329 ? 92.607  136.070 83.825  1.00 195.11 ? 329 SER B O   1 
ATOM   6487 C CB  . SER B 1 329 ? 92.364  136.075 80.567  1.00 195.11 ? 329 SER B CB  1 
ATOM   6488 O OG  . SER B 1 329 ? 91.375  135.141 80.176  1.00 195.11 ? 329 SER B OG  1 
ATOM   6489 N N   . THR B 1 330 ? 91.896  134.084 83.045  1.00 197.50 ? 330 THR B N   1 
ATOM   6490 C CA  . THR B 1 330 ? 91.036  133.799 84.187  1.00 197.50 ? 330 THR B CA  1 
ATOM   6491 C C   . THR B 1 330 ? 91.686  132.854 85.194  1.00 197.50 ? 330 THR B C   1 
ATOM   6492 O O   . THR B 1 330 ? 90.982  132.114 85.891  1.00 197.50 ? 330 THR B O   1 
ATOM   6493 C CB  . THR B 1 330 ? 89.701  133.228 83.712  1.00 197.50 ? 330 THR B CB  1 
ATOM   6494 O OG1 . THR B 1 330 ? 89.926  131.995 83.015  1.00 197.50 ? 330 THR B OG1 1 
ATOM   6495 C CG2 . THR B 1 330 ? 89.002  134.209 82.784  1.00 197.50 ? 330 THR B CG2 1 
ATOM   6496 N N   . LEU B 1 331 ? 93.013  132.859 85.285  1.00 194.20 ? 331 LEU B N   1 
ATOM   6497 C CA  . LEU B 1 331 ? 93.694  132.032 86.268  1.00 194.20 ? 331 LEU B CA  1 
ATOM   6498 C C   . LEU B 1 331 ? 93.491  132.589 87.675  1.00 194.20 ? 331 LEU B C   1 
ATOM   6499 O O   . LEU B 1 331 ? 93.108  133.745 87.870  1.00 194.20 ? 331 LEU B O   1 
ATOM   6500 C CB  . LEU B 1 331 ? 95.187  131.936 85.952  1.00 194.20 ? 331 LEU B CB  1 
ATOM   6501 C CG  . LEU B 1 331 ? 95.677  130.605 85.377  1.00 194.20 ? 331 LEU B CG  1 
ATOM   6502 C CD1 . LEU B 1 331 ? 97.195  130.581 85.291  1.00 194.20 ? 331 LEU B CD1 1 
ATOM   6503 C CD2 . LEU B 1 331 ? 95.165  129.436 86.207  1.00 194.20 ? 331 LEU B CD2 1 
ATOM   6504 N N   . LYS B 1 332 ? 93.731  131.737 88.663  1.00 189.61 ? 332 LYS B N   1 
ATOM   6505 C CA  . LYS B 1 332 ? 93.641  132.159 90.057  1.00 189.61 ? 332 LYS B CA  1 
ATOM   6506 C C   . LYS B 1 332 ? 94.895  132.932 90.449  1.00 189.61 ? 332 LYS B C   1 
ATOM   6507 O O   . LYS B 1 332 ? 96.009  132.452 90.215  1.00 189.61 ? 332 LYS B O   1 
ATOM   6508 C CB  . LYS B 1 332 ? 93.456  130.956 90.975  1.00 189.61 ? 332 LYS B CB  1 
ATOM   6509 C CG  . LYS B 1 332 ? 92.107  130.277 90.828  1.00 189.61 ? 332 LYS B CG  1 
ATOM   6510 C CD  . LYS B 1 332 ? 90.974  131.253 91.104  1.00 189.61 ? 332 LYS B CD  1 
ATOM   6511 C CE  . LYS B 1 332 ? 89.618  130.604 90.888  1.00 189.61 ? 332 LYS B CE  1 
ATOM   6512 N NZ  . LYS B 1 332 ? 88.504  131.546 91.179  1.00 189.61 ? 332 LYS B NZ  1 
ATOM   6513 N N   . PRO B 1 333 ? 94.757  134.132 91.018  1.00 191.51 ? 333 PRO B N   1 
ATOM   6514 C CA  . PRO B 1 333 ? 95.942  134.894 91.430  1.00 191.51 ? 333 PRO B CA  1 
ATOM   6515 C C   . PRO B 1 333 ? 96.728  134.168 92.513  1.00 191.51 ? 333 PRO B C   1 
ATOM   6516 O O   . PRO B 1 333 ? 96.153  133.535 93.402  1.00 191.51 ? 333 PRO B O   1 
ATOM   6517 C CB  . PRO B 1 333 ? 95.354  136.210 91.955  1.00 191.51 ? 333 PRO B CB  1 
ATOM   6518 C CG  . PRO B 1 333 ? 93.977  136.283 91.369  1.00 191.51 ? 333 PRO B CG  1 
ATOM   6519 C CD  . PRO B 1 333 ? 93.508  134.867 91.276  1.00 191.51 ? 333 PRO B CD  1 
ATOM   6520 N N   . ALA B 1 334 ? 98.056  134.278 92.428  1.00 188.98 ? 334 ALA B N   1 
ATOM   6521 C CA  . ALA B 1 334 ? 98.983  133.700 93.403  1.00 188.98 ? 334 ALA B CA  1 
ATOM   6522 C C   . ALA B 1 334 ? 98.754  132.199 93.583  1.00 188.98 ? 334 ALA B C   1 
ATOM   6523 O O   . ALA B 1 334 ? 98.690  131.683 94.701  1.00 188.98 ? 334 ALA B O   1 
ATOM   6524 C CB  . ALA B 1 334 ? 98.893  134.434 94.743  1.00 188.98 ? 334 ALA B CB  1 
ATOM   6525 N N   . GLU B 1 335 ? 98.631  131.494 92.463  1.00 188.91 ? 335 GLU B N   1 
ATOM   6526 C CA  . GLU B 1 335 ? 98.427  130.051 92.458  1.00 188.91 ? 335 GLU B CA  1 
ATOM   6527 C C   . GLU B 1 335 ? 99.684  129.367 91.939  1.00 188.91 ? 335 GLU B C   1 
ATOM   6528 O O   . GLU B 1 335 ? 100.205 129.737 90.881  1.00 188.91 ? 335 GLU B O   1 
ATOM   6529 C CB  . GLU B 1 335 ? 97.220  129.667 91.602  1.00 188.91 ? 335 GLU B CB  1 
ATOM   6530 C CG  . GLU B 1 335 ? 96.901  128.182 91.628  1.00 188.91 ? 335 GLU B CG  1 
ATOM   6531 C CD  . GLU B 1 335 ? 95.882  127.785 90.581  1.00 188.91 ? 335 GLU B CD  1 
ATOM   6532 O OE1 . GLU B 1 335 ? 95.467  128.660 89.794  1.00 188.91 ? 335 GLU B OE1 1 
ATOM   6533 O OE2 . GLU B 1 335 ? 95.500  126.596 90.542  1.00 188.91 ? 335 GLU B OE2 1 
ATOM   6534 N N   . SER B 1 336 ? 100.166 128.373 92.681  1.00 175.13 ? 336 SER B N   1 
ATOM   6535 C CA  . SER B 1 336 ? 101.402 127.693 92.321  1.00 175.13 ? 336 SER B CA  1 
ATOM   6536 C C   . SER B 1 336 ? 101.221 126.851 91.061  1.00 175.13 ? 336 SER B C   1 
ATOM   6537 O O   . SER B 1 336 ? 100.219 126.148 90.903  1.00 175.13 ? 336 SER B O   1 
ATOM   6538 C CB  . SER B 1 336 ? 101.878 126.822 93.483  1.00 175.13 ? 336 SER B CB  1 
ATOM   6539 O OG  . SER B 1 336 ? 103.288 126.677 93.475  1.00 175.13 ? 336 SER B OG  1 
ATOM   6540 N N   . VAL B 1 337 ? 102.206 126.926 90.161  1.00 170.72 ? 337 VAL B N   1 
ATOM   6541 C CA  . VAL B 1 337 ? 102.167 126.247 88.869  1.00 170.72 ? 337 VAL B CA  1 
ATOM   6542 C C   . VAL B 1 337 ? 103.531 125.623 88.598  1.00 170.72 ? 337 VAL B C   1 
ATOM   6543 O O   . VAL B 1 337 ? 104.523 125.928 89.258  1.00 170.72 ? 337 VAL B O   1 
ATOM   6544 C CB  . VAL B 1 337 ? 101.780 127.202 87.720  1.00 170.72 ? 337 VAL B CB  1 
ATOM   6545 C CG1 . VAL B 1 337 ? 100.321 127.622 87.836  1.00 170.72 ? 337 VAL B CG1 1 
ATOM   6546 C CG2 . VAL B 1 337 ? 102.695 128.415 87.705  1.00 170.72 ? 337 VAL B CG2 1 
ATOM   6547 N N   . THR B 1 338 ? 103.581 124.744 87.599  1.00 162.04 ? 338 THR B N   1 
ATOM   6548 C CA  . THR B 1 338 ? 104.804 124.045 87.231  1.00 162.04 ? 338 THR B CA  1 
ATOM   6549 C C   . THR B 1 338 ? 105.147 124.303 85.768  1.00 162.04 ? 338 THR B C   1 
ATOM   6550 O O   . THR B 1 338 ? 104.270 124.288 84.896  1.00 162.04 ? 338 THR B O   1 
ATOM   6551 C CB  . THR B 1 338 ? 104.677 122.539 87.480  1.00 162.04 ? 338 THR B CB  1 
ATOM   6552 O OG1 . THR B 1 338 ? 104.067 122.314 88.756  1.00 162.04 ? 338 THR B OG1 1 
ATOM   6553 C CG2 . THR B 1 338 ? 106.044 121.879 87.459  1.00 162.04 ? 338 THR B CG2 1 
ATOM   6554 N N   . LEU B 1 339 ? 106.432 124.523 85.503  1.00 155.11 ? 339 LEU B N   1 
ATOM   6555 C CA  . LEU B 1 339 ? 106.907 124.816 84.161  1.00 155.11 ? 339 LEU B CA  1 
ATOM   6556 C C   . LEU B 1 339 ? 108.106 123.942 83.826  1.00 155.11 ? 339 LEU B C   1 
ATOM   6557 O O   . LEU B 1 339 ? 108.892 123.567 84.703  1.00 155.11 ? 339 LEU B O   1 
ATOM   6558 C CB  . LEU B 1 339 ? 107.291 126.296 84.013  1.00 155.11 ? 339 LEU B CB  1 
ATOM   6559 C CG  . LEU B 1 339 ? 106.366 127.343 84.638  1.00 155.11 ? 339 LEU B CG  1 
ATOM   6560 C CD1 . LEU B 1 339 ? 107.002 128.724 84.579  1.00 155.11 ? 339 LEU B CD1 1 
ATOM   6561 C CD2 . LEU B 1 339 ? 105.010 127.350 83.955  1.00 155.11 ? 339 LEU B CD2 1 
ATOM   6562 N N   . VAL B 1 340 ? 108.240 123.627 82.539  1.00 144.18 ? 340 VAL B N   1 
ATOM   6563 C CA  . VAL B 1 340 ? 109.379 122.887 82.012  1.00 144.18 ? 340 VAL B CA  1 
ATOM   6564 C C   . VAL B 1 340 ? 110.190 123.828 81.135  1.00 144.18 ? 340 VAL B C   1 
ATOM   6565 O O   . VAL B 1 340 ? 109.650 124.763 80.531  1.00 144.18 ? 340 VAL B O   1 
ATOM   6566 C CB  . VAL B 1 340 ? 108.948 121.643 81.203  1.00 144.18 ? 340 VAL B CB  1 
ATOM   6567 C CG1 . VAL B 1 340 ? 108.589 120.495 82.122  1.00 144.18 ? 340 VAL B CG1 1 
ATOM   6568 C CG2 . VAL B 1 340 ? 107.784 121.979 80.302  1.00 144.18 ? 340 VAL B CG2 1 
ATOM   6569 N N   . GLY B 1 341 ? 111.491 123.585 81.065  1.00 145.35 ? 341 GLY B N   1 
ATOM   6570 C CA  . GLY B 1 341 ? 112.308 124.402 80.183  1.00 145.35 ? 341 GLY B CA  1 
ATOM   6571 C C   . GLY B 1 341 ? 113.785 124.295 80.527  1.00 145.35 ? 341 GLY B C   1 
ATOM   6572 O O   . GLY B 1 341 ? 114.244 123.274 81.040  1.00 145.35 ? 341 GLY B O   1 
ATOM   6573 N N   . GLN B 1 342 ? 114.502 125.372 80.222  1.00 154.89 ? 342 GLN B N   1 
ATOM   6574 C CA  . GLN B 1 342 ? 115.942 125.453 80.398  1.00 154.89 ? 342 GLN B CA  1 
ATOM   6575 C C   . GLN B 1 342 ? 116.276 125.636 81.882  1.00 154.89 ? 342 GLN B C   1 
ATOM   6576 O O   . GLN B 1 342 ? 115.411 125.941 82.707  1.00 154.89 ? 342 GLN B O   1 
ATOM   6577 C CB  . GLN B 1 342 ? 116.494 126.588 79.525  1.00 154.89 ? 342 GLN B CB  1 
ATOM   6578 C CG  . GLN B 1 342 ? 118.005 126.785 79.515  1.00 154.89 ? 342 GLN B CG  1 
ATOM   6579 C CD  . GLN B 1 342 ? 118.426 128.005 78.729  1.00 154.89 ? 342 GLN B CD  1 
ATOM   6580 O OE1 . GLN B 1 342 ? 117.768 129.045 78.774  1.00 154.89 ? 342 GLN B OE1 1 
ATOM   6581 N NE2 . GLN B 1 342 ? 119.528 127.887 77.997  1.00 154.89 ? 342 GLN B NE2 1 
ATOM   6582 N N   . LYS B 1 343 ? 117.552 125.418 82.218  1.00 153.21 ? 343 LYS B N   1 
ATOM   6583 C CA  . LYS B 1 343 ? 118.003 125.457 83.607  1.00 153.21 ? 343 LYS B CA  1 
ATOM   6584 C C   . LYS B 1 343 ? 117.716 126.807 84.259  1.00 153.21 ? 343 LYS B C   1 
ATOM   6585 O O   . LYS B 1 343 ? 117.217 126.867 85.389  1.00 153.21 ? 343 LYS B O   1 
ATOM   6586 C CB  . LYS B 1 343 ? 119.498 125.143 83.663  1.00 153.21 ? 343 LYS B CB  1 
ATOM   6587 C CG  . LYS B 1 343 ? 120.154 125.398 85.007  1.00 153.21 ? 343 LYS B CG  1 
ATOM   6588 C CD  . LYS B 1 343 ? 119.597 124.480 86.080  1.00 153.21 ? 343 LYS B CD  1 
ATOM   6589 C CE  . LYS B 1 343 ? 120.015 123.041 85.826  1.00 153.21 ? 343 LYS B CE  1 
ATOM   6590 N NZ  . LYS B 1 343 ? 121.495 122.884 85.846  1.00 153.21 ? 343 LYS B NZ  1 
ATOM   6591 N N   . ASP B 1 344 ? 118.021 127.904 83.561  1.00 158.87 ? 344 ASP B N   1 
ATOM   6592 C CA  . ASP B 1 344 ? 117.868 129.237 84.129  1.00 158.87 ? 344 ASP B CA  1 
ATOM   6593 C C   . ASP B 1 344 ? 116.695 130.022 83.561  1.00 158.87 ? 344 ASP B C   1 
ATOM   6594 O O   . ASP B 1 344 ? 116.223 130.952 84.221  1.00 158.87 ? 344 ASP B O   1 
ATOM   6595 C CB  . ASP B 1 344 ? 119.149 130.058 83.915  1.00 158.87 ? 344 ASP B CB  1 
ATOM   6596 C CG  . ASP B 1 344 ? 119.451 130.290 82.446  1.00 158.87 ? 344 ASP B CG  1 
ATOM   6597 O OD1 . ASP B 1 344 ? 119.690 129.302 81.719  1.00 158.87 ? 344 ASP B OD1 1 
ATOM   6598 O OD2 . ASP B 1 344 ? 119.445 131.464 82.018  1.00 158.87 ? 344 ASP B OD2 1 
ATOM   6599 N N   . ALA B 1 345 ? 116.218 129.674 82.364  1.00 156.67 ? 345 ALA B N   1 
ATOM   6600 C CA  . ALA B 1 345 ? 115.104 130.400 81.763  1.00 156.67 ? 345 ALA B CA  1 
ATOM   6601 C C   . ALA B 1 345 ? 113.825 130.232 82.572  1.00 156.67 ? 345 ALA B C   1 
ATOM   6602 O O   . ALA B 1 345 ? 113.035 131.180 82.699  1.00 156.67 ? 345 ALA B O   1 
ATOM   6603 C CB  . ALA B 1 345 ? 114.898 129.922 80.327  1.00 156.67 ? 345 ALA B CB  1 
ATOM   6604 N N   . VAL B 1 346 ? 113.615 129.038 83.127  1.00 160.26 ? 346 VAL B N   1 
ATOM   6605 C CA  . VAL B 1 346 ? 112.498 128.816 84.038  1.00 160.26 ? 346 VAL B CA  1 
ATOM   6606 C C   . VAL B 1 346 ? 112.617 129.732 85.247  1.00 160.26 ? 346 VAL B C   1 
ATOM   6607 O O   . VAL B 1 346 ? 111.624 130.299 85.716  1.00 160.26 ? 346 VAL B O   1 
ATOM   6608 C CB  . VAL B 1 346 ? 112.435 127.331 84.444  1.00 160.26 ? 346 VAL B CB  1 
ATOM   6609 C CG1 . VAL B 1 346 ? 111.578 127.136 85.685  1.00 160.26 ? 346 VAL B CG1 1 
ATOM   6610 C CG2 . VAL B 1 346 ? 111.909 126.489 83.288  1.00 160.26 ? 346 VAL B CG2 1 
ATOM   6611 N N   . SER B 1 347 ? 113.840 129.912 85.756  1.00 163.18 ? 347 SER B N   1 
ATOM   6612 C CA  . SER B 1 347 ? 114.050 130.834 86.868  1.00 163.18 ? 347 SER B CA  1 
ATOM   6613 C C   . SER B 1 347 ? 113.779 132.280 86.468  1.00 163.18 ? 347 SER B C   1 
ATOM   6614 O O   . SER B 1 347 ? 113.300 133.067 87.289  1.00 163.18 ? 347 SER B O   1 
ATOM   6615 C CB  . SER B 1 347 ? 115.473 130.693 87.410  1.00 163.18 ? 347 SER B CB  1 
ATOM   6616 O OG  . SER B 1 347 ? 115.589 131.287 88.691  1.00 163.18 ? 347 SER B OG  1 
ATOM   6617 N N   . GLU B 1 348 ? 114.073 132.652 85.219  1.00 166.65 ? 348 GLU B N   1 
ATOM   6618 C CA  . GLU B 1 348 ? 113.747 134.000 84.755  1.00 166.65 ? 348 GLU B CA  1 
ATOM   6619 C C   . GLU B 1 348 ? 112.242 134.228 84.755  1.00 166.65 ? 348 GLU B C   1 
ATOM   6620 O O   . GLU B 1 348 ? 111.748 135.240 85.280  1.00 166.65 ? 348 GLU B O   1 
ATOM   6621 C CB  . GLU B 1 348 ? 114.317 134.233 83.354  1.00 166.65 ? 348 GLU B CB  1 
ATOM   6622 C CG  . GLU B 1 348 ? 115.808 133.995 83.220  1.00 166.65 ? 348 GLU B CG  1 
ATOM   6623 C CD  . GLU B 1 348 ? 116.327 134.378 81.849  1.00 166.65 ? 348 GLU B CD  1 
ATOM   6624 O OE1 . GLU B 1 348 ? 115.872 135.407 81.307  1.00 166.65 ? 348 GLU B OE1 1 
ATOM   6625 O OE2 . GLU B 1 348 ? 117.196 133.657 81.315  1.00 166.65 ? 348 GLU B OE2 1 
ATOM   6626 N N   . VAL B 1 349 ? 111.493 133.280 84.180  1.00 167.80 ? 349 VAL B N   1 
ATOM   6627 C CA  . VAL B 1 349 ? 110.039 133.409 84.179  1.00 167.80 ? 349 VAL B CA  1 
ATOM   6628 C C   . VAL B 1 349 ? 109.500 133.381 85.604  1.00 167.80 ? 349 VAL B C   1 
ATOM   6629 O O   . VAL B 1 349 ? 108.535 134.085 85.919  1.00 167.80 ? 349 VAL B O   1 
ATOM   6630 C CB  . VAL B 1 349 ? 109.392 132.319 83.308  1.00 167.80 ? 349 VAL B CB  1 
ATOM   6631 C CG1 . VAL B 1 349 ? 107.920 132.630 83.075  1.00 167.80 ? 349 VAL B CG1 1 
ATOM   6632 C CG2 . VAL B 1 349 ? 110.108 132.217 81.978  1.00 167.80 ? 349 VAL B CG2 1 
ATOM   6633 N N   . GLN B 1 350 ? 110.127 132.601 86.488  1.00 171.83 ? 350 GLN B N   1 
ATOM   6634 C CA  . GLN B 1 350 ? 109.764 132.607 87.902  1.00 171.83 ? 350 GLN B CA  1 
ATOM   6635 C C   . GLN B 1 350 ? 109.944 133.989 88.512  1.00 171.83 ? 350 GLN B C   1 
ATOM   6636 O O   . GLN B 1 350 ? 109.060 134.489 89.217  1.00 171.83 ? 350 GLN B O   1 
ATOM   6637 C CB  . GLN B 1 350 ? 110.602 131.568 88.652  1.00 171.83 ? 350 GLN B CB  1 
ATOM   6638 C CG  . GLN B 1 350 ? 110.678 131.760 90.164  1.00 171.83 ? 350 GLN B CG  1 
ATOM   6639 C CD  . GLN B 1 350 ? 111.889 132.568 90.601  1.00 171.83 ? 350 GLN B CD  1 
ATOM   6640 O OE1 . GLN B 1 350 ? 113.025 132.246 90.249  1.00 171.83 ? 350 GLN B OE1 1 
ATOM   6641 N NE2 . GLN B 1 350 ? 111.650 133.627 91.366  1.00 171.83 ? 350 GLN B NE2 1 
ATOM   6642 N N   . SER B 1 351 ? 111.085 134.625 88.240  1.00 174.47 ? 351 SER B N   1 
ATOM   6643 C CA  . SER B 1 351 ? 111.335 135.962 88.762  1.00 174.47 ? 351 SER B CA  1 
ATOM   6644 C C   . SER B 1 351 ? 110.293 136.946 88.250  1.00 174.47 ? 351 SER B C   1 
ATOM   6645 O O   . SER B 1 351 ? 109.885 137.862 88.974  1.00 174.47 ? 351 SER B O   1 
ATOM   6646 C CB  . SER B 1 351 ? 112.745 136.420 88.386  1.00 174.47 ? 351 SER B CB  1 
ATOM   6647 O OG  . SER B 1 351 ? 112.885 136.562 86.984  1.00 174.47 ? 351 SER B OG  1 
ATOM   6648 N N   . GLN B 1 352 ? 109.840 136.768 87.010  1.00 173.59 ? 352 GLN B N   1 
ATOM   6649 C CA  . GLN B 1 352 ? 108.763 137.612 86.508  1.00 173.59 ? 352 GLN B CA  1 
ATOM   6650 C C   . GLN B 1 352 ? 107.367 137.118 86.883  1.00 173.59 ? 352 GLN B C   1 
ATOM   6651 O O   . GLN B 1 352 ? 106.390 137.800 86.555  1.00 173.59 ? 352 GLN B O   1 
ATOM   6652 C CB  . GLN B 1 352 ? 108.858 137.761 84.987  1.00 173.59 ? 352 GLN B CB  1 
ATOM   6653 C CG  . GLN B 1 352 ? 110.087 138.523 84.525  1.00 173.59 ? 352 GLN B CG  1 
ATOM   6654 C CD  . GLN B 1 352 ? 110.847 137.802 83.435  1.00 173.59 ? 352 GLN B CD  1 
ATOM   6655 O OE1 . GLN B 1 352 ? 110.419 136.752 82.954  1.00 173.59 ? 352 GLN B OE1 1 
ATOM   6656 N NE2 . GLN B 1 352 ? 111.987 138.356 83.042  1.00 173.59 ? 352 GLN B NE2 1 
ATOM   6657 N N   . LEU B 1 353 ? 107.233 135.970 87.550  1.00 176.95 ? 353 LEU B N   1 
ATOM   6658 C CA  . LEU B 1 353 ? 105.911 135.415 87.833  1.00 176.95 ? 353 LEU B CA  1 
ATOM   6659 C C   . LEU B 1 353 ? 105.584 135.289 89.315  1.00 176.95 ? 353 LEU B C   1 
ATOM   6660 O O   . LEU B 1 353 ? 104.427 135.482 89.693  1.00 176.95 ? 353 LEU B O   1 
ATOM   6661 C CB  . LEU B 1 353 ? 105.755 134.042 87.165  1.00 176.95 ? 353 LEU B CB  1 
ATOM   6662 C CG  . LEU B 1 353 ? 104.772 133.986 85.990  1.00 176.95 ? 353 LEU B CG  1 
ATOM   6663 C CD1 . LEU B 1 353 ? 104.377 132.555 85.649  1.00 176.95 ? 353 LEU B CD1 1 
ATOM   6664 C CD2 . LEU B 1 353 ? 103.536 134.830 86.277  1.00 176.95 ? 353 LEU B CD2 1 
ATOM   6665 N N   . GLY B 1 354 ? 106.547 134.962 90.170  1.00 173.36 ? 354 GLY B N   1 
ATOM   6666 C CA  . GLY B 1 354 ? 106.250 134.882 91.587  1.00 173.36 ? 354 GLY B CA  1 
ATOM   6667 C C   . GLY B 1 354 ? 107.408 134.320 92.384  1.00 173.36 ? 354 GLY B C   1 
ATOM   6668 O O   . GLY B 1 354 ? 108.470 133.988 91.848  1.00 173.36 ? 354 GLY B O   1 
ATOM   6669 N N   . ARG B 1 355 ? 107.174 134.219 93.691  1.00 166.23 ? 355 ARG B N   1 
ATOM   6670 C CA  . ARG B 1 355 ? 108.184 133.722 94.614  1.00 166.23 ? 355 ARG B CA  1 
ATOM   6671 C C   . ARG B 1 355 ? 108.394 132.223 94.414  1.00 166.23 ? 355 ARG B C   1 
ATOM   6672 O O   . ARG B 1 355 ? 107.497 131.501 93.975  1.00 166.23 ? 355 ARG B O   1 
ATOM   6673 C CB  . ARG B 1 355 ? 107.765 134.022 96.057  1.00 166.23 ? 355 ARG B CB  1 
ATOM   6674 C CG  . ARG B 1 355 ? 108.804 133.697 97.123  1.00 166.23 ? 355 ARG B CG  1 
ATOM   6675 C CD  . ARG B 1 355 ? 108.166 133.451 98.484  1.00 166.23 ? 355 ARG B CD  1 
ATOM   6676 N NE  . ARG B 1 355 ? 107.516 132.149 98.570  1.00 166.23 ? 355 ARG B NE  1 
ATOM   6677 C CZ  . ARG B 1 355 ? 106.249 131.965 98.920  1.00 166.23 ? 355 ARG B CZ  1 
ATOM   6678 N NH1 . ARG B 1 355 ? 105.460 132.982 99.223  1.00 166.23 ? 355 ARG B NH1 1 
ATOM   6679 N NH2 . ARG B 1 355 ? 105.764 130.727 98.970  1.00 166.23 ? 355 ARG B NH2 1 
ATOM   6680 N N   . LEU B 1 356 ? 109.602 131.759 94.723  1.00 167.85 ? 356 LEU B N   1 
ATOM   6681 C CA  . LEU B 1 356 ? 109.924 130.348 94.564  1.00 167.85 ? 356 LEU B CA  1 
ATOM   6682 C C   . LEU B 1 356 ? 109.136 129.493 95.554  1.00 167.85 ? 356 LEU B C   1 
ATOM   6683 O O   . LEU B 1 356 ? 108.890 129.888 96.696  1.00 167.85 ? 356 LEU B O   1 
ATOM   6684 C CB  . LEU B 1 356 ? 111.424 130.121 94.750  1.00 167.85 ? 356 LEU B CB  1 
ATOM   6685 C CG  . LEU B 1 356 ? 111.960 128.746 94.343  1.00 167.85 ? 356 LEU B CG  1 
ATOM   6686 C CD1 . LEU B 1 356 ? 112.401 128.750 92.887  1.00 167.85 ? 356 LEU B CD1 1 
ATOM   6687 C CD2 . LEU B 1 356 ? 113.101 128.322 95.254  1.00 167.85 ? 356 LEU B CD2 1 
ATOM   6688 N N   . ARG B 1 357 ? 108.739 128.307 95.098  1.00 159.28 ? 357 ARG B N   1 
ATOM   6689 C CA  . ARG B 1 357 ? 107.985 127.365 95.910  1.00 159.28 ? 357 ARG B CA  1 
ATOM   6690 C C   . ARG B 1 357 ? 108.954 126.432 96.641  1.00 159.28 ? 357 ARG B C   1 
ATOM   6691 O O   . ARG B 1 357 ? 110.171 126.633 96.633  1.00 159.28 ? 357 ARG B O   1 
ATOM   6692 C CB  . ARG B 1 357 ? 106.995 126.600 95.031  1.00 159.28 ? 357 ARG B CB  1 
ATOM   6693 C CG  . ARG B 1 357 ? 105.726 126.142 95.739  1.00 159.28 ? 357 ARG B CG  1 
ATOM   6694 C CD  . ARG B 1 357 ? 105.411 124.697 95.389  1.00 159.28 ? 357 ARG B CD  1 
ATOM   6695 N NE  . ARG B 1 357 ? 104.171 124.236 96.000  1.00 159.28 ? 357 ARG B NE  1 
ATOM   6696 C CZ  . ARG B 1 357 ? 104.095 123.243 96.876  1.00 159.28 ? 357 ARG B CZ  1 
ATOM   6697 N NH1 . ARG B 1 357 ? 105.174 122.587 97.272  1.00 159.28 ? 357 ARG B NH1 1 
ATOM   6698 N NH2 . ARG B 1 357 ? 102.908 122.901 97.368  1.00 159.28 ? 357 ARG B NH2 1 
ATOM   6699 N N   . ALA B 1 358 ? 108.418 125.395 97.283  1.00 148.63 ? 358 ALA B N   1 
ATOM   6700 C CA  . ALA B 1 358 ? 109.210 124.432 98.029  1.00 148.63 ? 358 ALA B CA  1 
ATOM   6701 C C   . ALA B 1 358 ? 108.856 123.022 97.580  1.00 148.63 ? 358 ALA B C   1 
ATOM   6702 O O   . ALA B 1 358 ? 107.779 122.772 97.032  1.00 148.63 ? 358 ALA B O   1 
ATOM   6703 C CB  . ALA B 1 358 ? 108.995 124.575 99.542  1.00 148.63 ? 358 ALA B CB  1 
ATOM   6704 N N   . ALA B 1 359 ? 109.782 122.099 97.821  1.00 135.03 ? 359 ALA B N   1 
ATOM   6705 C CA  . ALA B 1 359 ? 109.631 120.725 97.370  1.00 135.03 ? 359 ALA B CA  1 
ATOM   6706 C C   . ALA B 1 359 ? 108.683 119.947 98.279  1.00 135.03 ? 359 ALA B C   1 
ATOM   6707 O O   . ALA B 1 359 ? 108.379 120.352 99.404  1.00 135.03 ? 359 ALA B O   1 
ATOM   6708 C CB  . ALA B 1 359 ? 110.989 120.029 97.308  1.00 135.03 ? 359 ALA B CB  1 
ATOM   6709 N N   . GLU B 1 360 ? 108.213 118.809 97.764  1.00 118.26 ? 360 GLU B N   1 
ATOM   6710 C CA  . GLU B 1 360 ? 107.266 117.973 98.495  1.00 118.26 ? 360 GLU B CA  1 
ATOM   6711 C C   . GLU B 1 360 ? 107.946 117.162 99.595  1.00 118.26 ? 360 GLU B C   1 
ATOM   6712 O O   . GLU B 1 360 ? 107.379 116.988 100.680 1.00 118.26 ? 360 GLU B O   1 
ATOM   6713 C CB  . GLU B 1 360 ? 106.540 117.051 97.510  1.00 118.26 ? 360 GLU B CB  1 
ATOM   6714 C CG  . GLU B 1 360 ? 106.115 115.702 98.071  1.00 118.26 ? 360 GLU B CG  1 
ATOM   6715 C CD  . GLU B 1 360 ? 104.838 115.781 98.881  1.00 118.26 ? 360 GLU B CD  1 
ATOM   6716 O OE1 . GLU B 1 360 ? 103.796 116.176 98.315  1.00 118.26 ? 360 GLU B OE1 1 
ATOM   6717 O OE2 . GLU B 1 360 ? 104.873 115.449 100.084 1.00 118.26 ? 360 GLU B OE2 1 
ATOM   6718 N N   . ASN B 1 361 ? 109.164 116.676 99.339  1.00 119.71 ? 361 ASN B N   1 
ATOM   6719 C CA  . ASN B 1 361 ? 109.796 115.713 100.239 1.00 119.71 ? 361 ASN B CA  1 
ATOM   6720 C C   . ASN B 1 361 ? 110.142 116.329 101.592 1.00 119.71 ? 361 ASN B C   1 
ATOM   6721 O O   . ASN B 1 361 ? 110.036 115.659 102.625 1.00 119.71 ? 361 ASN B O   1 
ATOM   6722 C CB  . ASN B 1 361 ? 111.044 115.124 99.581  1.00 119.71 ? 361 ASN B CB  1 
ATOM   6723 C CG  . ASN B 1 361 ? 111.956 116.187 99.002  1.00 119.71 ? 361 ASN B CG  1 
ATOM   6724 O OD1 . ASN B 1 361 ? 111.687 117.383 99.117  1.00 119.71 ? 361 ASN B OD1 1 
ATOM   6725 N ND2 . ASN B 1 361 ? 113.045 115.756 98.376  1.00 119.71 ? 361 ASN B ND2 1 
ATOM   6726 N N   . ILE B 1 362 ? 110.577 117.591 101.608 1.00 108.90 ? 362 ILE B N   1 
ATOM   6727 C CA  . ILE B 1 362 ? 111.010 118.221 102.852 1.00 108.90 ? 362 ILE B CA  1 
ATOM   6728 C C   . ILE B 1 362 ? 109.824 118.400 103.791 1.00 108.90 ? 362 ILE B C   1 
ATOM   6729 O O   . ILE B 1 362 ? 108.692 118.649 103.357 1.00 108.90 ? 362 ILE B O   1 
ATOM   6730 C CB  . ILE B 1 362 ? 111.707 119.561 102.565 1.00 108.90 ? 362 ILE B CB  1 
ATOM   6731 C CG1 . ILE B 1 362 ? 110.911 120.372 101.540 1.00 108.90 ? 362 ILE B CG1 1 
ATOM   6732 C CG2 . ILE B 1 362 ? 113.132 119.329 102.084 1.00 108.90 ? 362 ILE B CG2 1 
ATOM   6733 C CD1 . ILE B 1 362 ? 111.581 121.666 101.131 1.00 108.90 ? 362 ILE B CD1 1 
ATOM   6734 N N   . ILE B 1 363 ? 110.082 118.266 105.093 1.00 79.73  ? 363 ILE B N   1 
ATOM   6735 C CA  . ILE B 1 363 ? 109.054 118.279 106.128 1.00 79.73  ? 363 ILE B CA  1 
ATOM   6736 C C   . ILE B 1 363 ? 109.343 119.421 107.091 1.00 79.73  ? 363 ILE B C   1 
ATOM   6737 O O   . ILE B 1 363 ? 110.500 119.639 107.471 1.00 79.73  ? 363 ILE B O   1 
ATOM   6738 C CB  . ILE B 1 363 ? 108.996 116.939 106.888 1.00 79.73  ? 363 ILE B CB  1 
ATOM   6739 C CG1 . ILE B 1 363 ? 109.320 115.772 105.954 1.00 79.73  ? 363 ILE B CG1 1 
ATOM   6740 C CG2 . ILE B 1 363 ? 107.635 116.754 107.538 1.00 79.73  ? 363 ILE B CG2 1 
ATOM   6741 C CD1 . ILE B 1 363 ? 109.688 114.495 106.682 1.00 79.73  ? 363 ILE B CD1 1 
ATOM   6742 N N   . ASN B 1 364 ? 108.297 120.151 107.484 1.00 64.30  ? 364 ASN B N   1 
ATOM   6743 C CA  . ASN B 1 364 ? 108.434 121.243 108.451 1.00 64.30  ? 364 ASN B CA  1 
ATOM   6744 C C   . ASN B 1 364 ? 108.215 120.701 109.860 1.00 64.30  ? 364 ASN B C   1 
ATOM   6745 O O   . ASN B 1 364 ? 107.090 120.644 110.377 1.00 64.30  ? 364 ASN B O   1 
ATOM   6746 C CB  . ASN B 1 364 ? 107.481 122.383 108.122 1.00 64.30  ? 364 ASN B CB  1 
ATOM   6747 C CG  . ASN B 1 364 ? 108.158 123.491 107.336 1.00 64.30  ? 364 ASN B CG  1 
ATOM   6748 O OD1 . ASN B 1 364 ? 109.366 123.450 107.104 1.00 64.30  ? 364 ASN B OD1 1 
ATOM   6749 N ND2 . ASN B 1 364 ? 107.385 124.489 106.931 1.00 64.30  ? 364 ASN B ND2 1 
ATOM   6750 N N   . TYR B 1 365 ? 109.325 120.317 110.495 1.00 54.02  ? 365 TYR B N   1 
ATOM   6751 C CA  . TYR B 1 365 ? 109.271 119.786 111.850 1.00 54.02  ? 365 TYR B CA  1 
ATOM   6752 C C   . TYR B 1 365 ? 108.783 120.837 112.837 1.00 54.02  ? 365 TYR B C   1 
ATOM   6753 O O   . TYR B 1 365 ? 108.165 120.496 113.853 1.00 54.02  ? 365 TYR B O   1 
ATOM   6754 C CB  . TYR B 1 365 ? 110.651 119.271 112.253 1.00 54.02  ? 365 TYR B CB  1 
ATOM   6755 C CG  . TYR B 1 365 ? 111.108 118.093 111.425 1.00 54.02  ? 365 TYR B CG  1 
ATOM   6756 C CD1 . TYR B 1 365 ? 110.399 116.903 111.426 1.00 54.02  ? 365 TYR B CD1 1 
ATOM   6757 C CD2 . TYR B 1 365 ? 112.245 118.178 110.634 1.00 54.02  ? 365 TYR B CD2 1 
ATOM   6758 C CE1 . TYR B 1 365 ? 110.810 115.827 110.668 1.00 54.02  ? 365 TYR B CE1 1 
ATOM   6759 C CE2 . TYR B 1 365 ? 112.665 117.107 109.872 1.00 54.02  ? 365 TYR B CE2 1 
ATOM   6760 C CZ  . TYR B 1 365 ? 111.944 115.934 109.892 1.00 54.02  ? 365 TYR B CZ  1 
ATOM   6761 O OH  . TYR B 1 365 ? 112.354 114.862 109.136 1.00 54.02  ? 365 TYR B OH  1 
ATOM   6762 N N   . SER B 1 366 ? 109.052 122.115 112.556 1.00 49.68  ? 366 SER B N   1 
ATOM   6763 C CA  . SER B 1 366 ? 108.518 123.183 113.392 1.00 49.68  ? 366 SER B CA  1 
ATOM   6764 C C   . SER B 1 366 ? 106.997 123.195 113.357 1.00 49.68  ? 366 SER B C   1 
ATOM   6765 O O   . SER B 1 366 ? 106.348 123.334 114.401 1.00 49.68  ? 366 SER B O   1 
ATOM   6766 C CB  . SER B 1 366 ? 109.075 124.531 112.942 1.00 49.68  ? 366 SER B CB  1 
ATOM   6767 O OG  . SER B 1 366 ? 108.783 124.765 111.576 1.00 49.68  ? 366 SER B OG  1 
ATOM   6768 N N   . TRP B 1 367 ? 106.409 123.037 112.168 1.00 51.61  ? 367 TRP B N   1 
ATOM   6769 C CA  . TRP B 1 367 ? 104.955 122.947 112.072 1.00 51.61  ? 367 TRP B CA  1 
ATOM   6770 C C   . TRP B 1 367 ? 104.423 121.711 112.784 1.00 51.61  ? 367 TRP B C   1 
ATOM   6771 O O   . TRP B 1 367 ? 103.378 121.773 113.440 1.00 51.61  ? 367 TRP B O   1 
ATOM   6772 C CB  . TRP B 1 367 ? 104.511 122.959 110.609 1.00 51.61  ? 367 TRP B CB  1 
ATOM   6773 C CG  . TRP B 1 367 ? 103.469 123.999 110.319 1.00 51.61  ? 367 TRP B CG  1 
ATOM   6774 C CD1 . TRP B 1 367 ? 102.187 123.773 109.911 1.00 51.61  ? 367 TRP B CD1 1 
ATOM   6775 C CD2 . TRP B 1 367 ? 103.605 125.420 110.440 1.00 51.61  ? 367 TRP B CD2 1 
ATOM   6776 N NE1 . TRP B 1 367 ? 101.520 124.961 109.760 1.00 51.61  ? 367 TRP B NE1 1 
ATOM   6777 C CE2 . TRP B 1 367 ? 102.367 125.989 110.078 1.00 51.61  ? 367 TRP B CE2 1 
ATOM   6778 C CE3 . TRP B 1 367 ? 104.653 126.268 110.811 1.00 51.61  ? 367 TRP B CE3 1 
ATOM   6779 C CZ2 . TRP B 1 367 ? 102.150 127.364 110.077 1.00 51.61  ? 367 TRP B CZ2 1 
ATOM   6780 C CZ3 . TRP B 1 367 ? 104.434 127.633 110.810 1.00 51.61  ? 367 TRP B CZ3 1 
ATOM   6781 C CH2 . TRP B 1 367 ? 103.193 128.168 110.445 1.00 51.61  ? 367 TRP B CH2 1 
ATOM   6782 N N   . PHE B 1 368 ? 105.130 120.583 112.672 1.00 35.92  ? 368 PHE B N   1 
ATOM   6783 C CA  . PHE B 1 368 ? 104.707 119.378 113.386 1.00 35.92  ? 368 PHE B CA  1 
ATOM   6784 C C   . PHE B 1 368 ? 104.663 119.611 114.897 1.00 35.92  ? 368 PHE B C   1 
ATOM   6785 O O   . PHE B 1 368 ? 103.653 119.323 115.563 1.00 35.92  ? 368 PHE B O   1 
ATOM   6786 C CB  . PHE B 1 368 ? 105.647 118.225 113.046 1.00 35.92  ? 368 PHE B CB  1 
ATOM   6787 C CG  . PHE B 1 368 ? 105.065 116.873 113.305 1.00 35.92  ? 368 PHE B CG  1 
ATOM   6788 C CD1 . PHE B 1 368 ? 103.935 116.453 112.630 1.00 35.92  ? 368 PHE B CD1 1 
ATOM   6789 C CD2 . PHE B 1 368 ? 105.647 116.024 114.226 1.00 35.92  ? 368 PHE B CD2 1 
ATOM   6790 C CE1 . PHE B 1 368 ? 103.397 115.207 112.871 1.00 35.92  ? 368 PHE B CE1 1 
ATOM   6791 C CE2 . PHE B 1 368 ? 105.112 114.778 114.471 1.00 35.92  ? 368 PHE B CE2 1 
ATOM   6792 C CZ  . PHE B 1 368 ? 103.985 114.371 113.793 1.00 35.92  ? 368 PHE B CZ  1 
ATOM   6793 N N   . ALA B 1 369 ? 105.753 120.146 115.452 1.00 34.95  ? 369 ALA B N   1 
ATOM   6794 C CA  . ALA B 1 369 ? 105.820 120.375 116.891 1.00 34.95  ? 369 ALA B CA  1 
ATOM   6795 C C   . ALA B 1 369 ? 104.800 121.414 117.341 1.00 34.95  ? 369 ALA B C   1 
ATOM   6796 O O   . ALA B 1 369 ? 104.185 121.270 118.406 1.00 34.95  ? 369 ALA B O   1 
ATOM   6797 C CB  . ALA B 1 369 ? 107.232 120.801 117.289 1.00 34.95  ? 369 ALA B CB  1 
ATOM   6798 N N   . LEU B 1 370 ? 104.609 122.472 116.549 1.00 33.85  ? 370 LEU B N   1 
ATOM   6799 C CA  . LEU B 1 370 ? 103.621 123.486 116.900 1.00 33.85  ? 370 LEU B CA  1 
ATOM   6800 C C   . LEU B 1 370 ? 102.215 122.906 116.887 1.00 33.85  ? 370 LEU B C   1 
ATOM   6801 O O   . LEU B 1 370 ? 101.385 123.260 117.733 1.00 33.85  ? 370 LEU B O   1 
ATOM   6802 C CB  . LEU B 1 370 ? 103.726 124.677 115.950 1.00 33.85  ? 370 LEU B CB  1 
ATOM   6803 C CG  . LEU B 1 370 ? 103.123 125.979 116.477 1.00 33.85  ? 370 LEU B CG  1 
ATOM   6804 C CD1 . LEU B 1 370 ? 103.907 126.475 117.679 1.00 33.85  ? 370 LEU B CD1 1 
ATOM   6805 C CD2 . LEU B 1 370 ? 103.089 127.035 115.388 1.00 33.85  ? 370 LEU B CD2 1 
ATOM   6806 N N   . GLY B 1 371 ? 101.928 122.010 115.941 1.00 33.93  ? 371 GLY B N   1 
ATOM   6807 C CA  . GLY B 1 371 ? 100.634 121.352 115.930 1.00 33.93  ? 371 GLY B CA  1 
ATOM   6808 C C   . GLY B 1 371 ? 100.404 120.502 117.165 1.00 33.93  ? 371 GLY B C   1 
ATOM   6809 O O   . GLY B 1 371 ? 99.320  120.532 117.755 1.00 33.93  ? 371 GLY B O   1 
ATOM   6810 N N   . ILE B 1 372 ? 101.424 119.746 117.582 1.00 32.47  ? 372 ILE B N   1 
ATOM   6811 C CA  . ILE B 1 372 ? 101.284 118.943 118.801 1.00 32.47  ? 372 ILE B CA  1 
ATOM   6812 C C   . ILE B 1 372 ? 101.062 119.838 120.020 1.00 32.47  ? 372 ILE B C   1 
ATOM   6813 O O   . ILE B 1 372 ? 100.202 119.559 120.872 1.00 32.47  ? 372 ILE B O   1 
ATOM   6814 C CB  . ILE B 1 372 ? 102.505 118.023 118.988 1.00 32.47  ? 372 ILE B CB  1 
ATOM   6815 C CG1 . ILE B 1 372 ? 102.711 117.150 117.752 1.00 32.47  ? 372 ILE B CG1 1 
ATOM   6816 C CG2 . ILE B 1 372 ? 102.332 117.153 120.219 1.00 32.47  ? 372 ILE B CG2 1 
ATOM   6817 C CD1 . ILE B 1 372 ? 101.598 116.160 117.518 1.00 32.47  ? 372 ILE B CD1 1 
ATOM   6818 N N   . ALA B 1 373 ? 101.832 120.926 120.122 1.00 33.30  ? 373 ALA B N   1 
ATOM   6819 C CA  . ALA B 1 373 ? 101.698 121.829 121.263 1.00 33.30  ? 373 ALA B CA  1 
ATOM   6820 C C   . ALA B 1 373 ? 100.322 122.486 121.298 1.00 33.30  ? 373 ALA B C   1 
ATOM   6821 O O   . ALA B 1 373 ? 99.707  122.601 122.367 1.00 33.30  ? 373 ALA B O   1 
ATOM   6822 C CB  . ALA B 1 373 ? 102.796 122.890 121.224 1.00 33.30  ? 373 ALA B CB  1 
ATOM   6823 N N   . LEU B 1 374 ? 99.823  122.925 120.141 1.00 36.03  ? 374 LEU B N   1 
ATOM   6824 C CA  . LEU B 1 374 ? 98.494  123.522 120.092 1.00 36.03  ? 374 LEU B CA  1 
ATOM   6825 C C   . LEU B 1 374 ? 97.416  122.495 120.408 1.00 36.03  ? 374 LEU B C   1 
ATOM   6826 O O   . LEU B 1 374 ? 96.389  122.837 121.003 1.00 36.03  ? 374 LEU B O   1 
ATOM   6827 C CB  . LEU B 1 374 ? 98.247  124.157 118.725 1.00 36.03  ? 374 LEU B CB  1 
ATOM   6828 C CG  . LEU B 1 374 ? 98.977  125.471 118.449 1.00 36.03  ? 374 LEU B CG  1 
ATOM   6829 C CD1 . LEU B 1 374 ? 98.394  126.151 117.221 1.00 36.03  ? 374 LEU B CD1 1 
ATOM   6830 C CD2 . LEU B 1 374 ? 98.909  126.389 119.659 1.00 36.03  ? 374 LEU B CD2 1 
ATOM   6831 N N   . SER B 1 375 ? 97.627  121.235 120.019 1.00 35.25  ? 375 SER B N   1 
ATOM   6832 C CA  . SER B 1 375 ? 96.679  120.188 120.385 1.00 35.25  ? 375 SER B CA  1 
ATOM   6833 C C   . SER B 1 375 ? 96.602  120.021 121.897 1.00 35.25  ? 375 SER B C   1 
ATOM   6834 O O   . SER B 1 375 ? 95.506  119.927 122.464 1.00 35.25  ? 375 SER B O   1 
ATOM   6835 C CB  . SER B 1 375 ? 97.070  118.869 119.722 1.00 35.25  ? 375 SER B CB  1 
ATOM   6836 O OG  . SER B 1 375 ? 97.957  118.134 120.547 1.00 35.25  ? 375 SER B OG  1 
ATOM   6837 N N   . ALA B 1 376 ? 97.757  119.997 122.567 1.00 37.02  ? 376 ALA B N   1 
ATOM   6838 C CA  . ALA B 1 376 ? 97.750  119.895 124.027 1.00 37.02  ? 376 ALA B CA  1 
ATOM   6839 C C   . ALA B 1 376 ? 97.087  121.112 124.669 1.00 37.02  ? 376 ALA B C   1 
ATOM   6840 O O   . ALA B 1 376 ? 96.283  120.978 125.606 1.00 37.02  ? 376 ALA B O   1 
ATOM   6841 C CB  . ALA B 1 376 ? 99.175  119.721 124.549 1.00 37.02  ? 376 ALA B CB  1 
ATOM   6842 N N   . ALA B 1 377 ? 97.402  122.310 124.168 1.00 41.13  ? 377 ALA B N   1 
ATOM   6843 C CA  . ALA B 1 377 ? 96.815  123.524 124.727 1.00 41.13  ? 377 ALA B CA  1 
ATOM   6844 C C   . ALA B 1 377 ? 95.301  123.543 124.551 1.00 41.13  ? 377 ALA B C   1 
ATOM   6845 O O   . ALA B 1 377 ? 94.567  123.942 125.463 1.00 41.13  ? 377 ALA B O   1 
ATOM   6846 C CB  . ALA B 1 377 ? 97.443  124.759 124.083 1.00 41.13  ? 377 ALA B CB  1 
ATOM   6847 N N   . LEU B 1 378 ? 94.814  123.117 123.383 1.00 44.00  ? 378 LEU B N   1 
ATOM   6848 C CA  . LEU B 1 378 ? 93.374  123.041 123.158 1.00 44.00  ? 378 LEU B CA  1 
ATOM   6849 C C   . LEU B 1 378 ? 92.728  121.993 124.051 1.00 44.00  ? 378 LEU B C   1 
ATOM   6850 O O   . LEU B 1 378 ? 91.616  122.197 124.550 1.00 44.00  ? 378 LEU B O   1 
ATOM   6851 C CB  . LEU B 1 378 ? 93.087  122.743 121.688 1.00 44.00  ? 378 LEU B CB  1 
ATOM   6852 C CG  . LEU B 1 378 ? 91.747  123.249 121.154 1.00 44.00  ? 378 LEU B CG  1 
ATOM   6853 C CD1 . LEU B 1 378 ? 91.442  124.643 121.682 1.00 44.00  ? 378 LEU B CD1 1 
ATOM   6854 C CD2 . LEU B 1 378 ? 91.741  123.236 119.635 1.00 44.00  ? 378 LEU B CD2 1 
ATOM   6855 N N   . GLY B 1 379 ? 93.403  120.860 124.261 1.00 47.12  ? 379 GLY B N   1 
ATOM   6856 C CA  . GLY B 1 379 ? 92.874  119.856 125.166 1.00 47.12  ? 379 GLY B CA  1 
ATOM   6857 C C   . GLY B 1 379 ? 92.811  120.309 126.608 1.00 47.12  ? 379 GLY B C   1 
ATOM   6858 O O   . GLY B 1 379 ? 92.029  119.755 127.387 1.00 47.12  ? 379 GLY B O   1 
ATOM   6859 N N   . ILE B 1 380 ? 93.628  121.298 126.980 1.00 52.19  ? 380 ILE B N   1 
ATOM   6860 C CA  . ILE B 1 380 ? 93.597  121.804 128.354 1.00 52.19  ? 380 ILE B CA  1 
ATOM   6861 C C   . ILE B 1 380 ? 92.243  122.424 128.692 1.00 52.19  ? 380 ILE B C   1 
ATOM   6862 O O   . ILE B 1 380 ? 91.712  122.212 129.790 1.00 52.19  ? 380 ILE B O   1 
ATOM   6863 C CB  . ILE B 1 380 ? 94.750  122.797 128.585 1.00 52.19  ? 380 ILE B CB  1 
ATOM   6864 C CG1 . ILE B 1 380 ? 96.062  122.028 128.683 1.00 52.19  ? 380 ILE B CG1 1 
ATOM   6865 C CG2 . ILE B 1 380 ? 94.515  123.638 129.834 1.00 52.19  ? 380 ILE B CG2 1 
ATOM   6866 C CD1 . ILE B 1 380 ? 96.204  121.305 130.000 1.00 52.19  ? 380 ILE B CD1 1 
ATOM   6867 N N   . VAL B 1 381 ? 91.665  123.196 127.765 1.00 59.45  ? 381 VAL B N   1 
ATOM   6868 C CA  . VAL B 1 381 ? 90.457  123.959 128.072 1.00 59.45  ? 381 VAL B CA  1 
ATOM   6869 C C   . VAL B 1 381 ? 89.310  123.024 128.462 1.00 59.45  ? 381 VAL B C   1 
ATOM   6870 O O   . VAL B 1 381 ? 89.228  121.873 128.014 1.00 59.45  ? 381 VAL B O   1 
ATOM   6871 C CB  . VAL B 1 381 ? 90.060  124.865 126.891 1.00 59.45  ? 381 VAL B CB  1 
ATOM   6872 C CG1 . VAL B 1 381 ? 89.325  124.083 125.807 1.00 59.45  ? 381 VAL B CG1 1 
ATOM   6873 C CG2 . VAL B 1 381 ? 89.222  126.044 127.371 1.00 59.45  ? 381 VAL B CG2 1 
ATOM   6874 N N   . GLY B 1 382 ? 88.441  123.514 129.343 1.00 76.05  ? 382 GLY B N   1 
ATOM   6875 C CA  . GLY B 1 382 ? 87.337  122.713 129.834 1.00 76.05  ? 382 GLY B CA  1 
ATOM   6876 C C   . GLY B 1 382 ? 86.258  123.577 130.439 1.00 76.05  ? 382 GLY B C   1 
ATOM   6877 O O   . GLY B 1 382 ? 86.515  124.697 130.894 1.00 76.05  ? 382 GLY B O   1 
ATOM   6878 N N   . THR B 1 383 ? 85.037  123.047 130.447 1.00 89.51  ? 383 THR B N   1 
ATOM   6879 C CA  . THR B 1 383 ? 83.882  123.735 131.006 1.00 89.51  ? 383 THR B CA  1 
ATOM   6880 C C   . THR B 1 383 ? 83.225  122.837 132.042 1.00 89.51  ? 383 THR B C   1 
ATOM   6881 O O   . THR B 1 383 ? 83.509  121.641 132.120 1.00 89.51  ? 383 THR B O   1 
ATOM   6882 C CB  . THR B 1 383 ? 82.852  124.120 129.928 1.00 89.51  ? 383 THR B CB  1 
ATOM   6883 O OG1 . THR B 1 383 ? 81.931  123.038 129.736 1.00 89.51  ? 383 THR B OG1 1 
ATOM   6884 C CG2 . THR B 1 383 ? 83.535  124.440 128.605 1.00 89.51  ? 383 THR B CG2 1 
ATOM   6885 N N   . LYS B 1 384 ? 82.363  123.430 132.862 1.00 105.53 ? 384 LYS B N   1 
ATOM   6886 C CA  . LYS B 1 384 ? 81.606  122.691 133.861 1.00 105.53 ? 384 LYS B CA  1 
ATOM   6887 C C   . LYS B 1 384 ? 80.122  122.728 133.523 1.00 105.53 ? 384 LYS B C   1 
ATOM   6888 O O   . LYS B 1 384 ? 79.591  123.769 133.117 1.00 105.53 ? 384 LYS B O   1 
ATOM   6889 C CB  . LYS B 1 384 ? 81.843  123.250 135.270 1.00 105.53 ? 384 LYS B CB  1 
ATOM   6890 C CG  . LYS B 1 384 ? 81.520  124.727 135.442 1.00 105.53 ? 384 LYS B CG  1 
ATOM   6891 C CD  . LYS B 1 384 ? 81.705  125.165 136.888 1.00 105.53 ? 384 LYS B CD  1 
ATOM   6892 C CE  . LYS B 1 384 ? 83.116  124.891 137.378 1.00 105.53 ? 384 LYS B CE  1 
ATOM   6893 N NZ  . LYS B 1 384 ? 84.125  125.712 136.654 1.00 105.53 ? 384 LYS B NZ  1 
ATOM   6894 N N   . VAL B 1 385 ? 79.461  121.583 133.669 1.00 112.64 ? 385 VAL B N   1 
ATOM   6895 C CA  . VAL B 1 385 ? 78.025  121.457 133.440 1.00 112.64 ? 385 VAL B CA  1 
ATOM   6896 C C   . VAL B 1 385 ? 77.420  120.776 134.668 1.00 112.64 ? 385 VAL B C   1 
ATOM   6897 O O   . VAL B 1 385 ? 77.508  119.554 134.824 1.00 112.64 ? 385 VAL B O   1 
ATOM   6898 C CB  . VAL B 1 385 ? 77.699  120.708 132.137 1.00 112.64 ? 385 VAL B CB  1 
ATOM   6899 C CG1 . VAL B 1 385 ? 78.527  119.423 131.985 1.00 112.64 ? 385 VAL B CG1 1 
ATOM   6900 C CG2 . VAL B 1 385 ? 76.204  120.413 132.041 1.00 112.64 ? 385 VAL B CG2 1 
ATOM   6901 N N   . SER B 1 386 ? 76.820  121.576 135.553 1.00 121.71 ? 386 SER B N   1 
ATOM   6902 C CA  . SER B 1 386 ? 76.203  121.092 136.790 1.00 121.71 ? 386 SER B CA  1 
ATOM   6903 C C   . SER B 1 386 ? 77.189  120.278 137.629 1.00 121.71 ? 386 SER B C   1 
ATOM   6904 O O   . SER B 1 386 ? 76.873  119.201 138.138 1.00 121.71 ? 386 SER B O   1 
ATOM   6905 C CB  . SER B 1 386 ? 74.936  120.286 136.493 1.00 121.71 ? 386 SER B CB  1 
ATOM   6906 O OG  . SER B 1 386 ? 74.057  121.012 135.653 1.00 121.71 ? 386 SER B OG  1 
ATOM   6907 N N   . GLY B 1 387 ? 78.402  120.807 137.768 1.00 117.62 ? 387 GLY B N   1 
ATOM   6908 C CA  . GLY B 1 387 ? 79.422  120.161 138.567 1.00 117.62 ? 387 GLY B CA  1 
ATOM   6909 C C   . GLY B 1 387 ? 80.231  119.096 137.863 1.00 117.62 ? 387 GLY B C   1 
ATOM   6910 O O   . GLY B 1 387 ? 80.987  118.378 138.528 1.00 117.62 ? 387 GLY B O   1 
ATOM   6911 N N   . VAL B 1 388 ? 80.101  118.964 136.547 1.00 102.62 ? 388 VAL B N   1 
ATOM   6912 C CA  . VAL B 1 388 ? 80.855  117.985 135.773 1.00 102.62 ? 388 VAL B CA  1 
ATOM   6913 C C   . VAL B 1 388 ? 81.943  118.737 135.008 1.00 102.62 ? 388 VAL B C   1 
ATOM   6914 O O   . VAL B 1 388 ? 81.643  119.416 134.015 1.00 102.62 ? 388 VAL B O   1 
ATOM   6915 C CB  . VAL B 1 388 ? 79.951  117.198 134.815 1.00 102.62 ? 388 VAL B CB  1 
ATOM   6916 C CG1 . VAL B 1 388 ? 80.708  116.021 134.224 1.00 102.62 ? 388 VAL B CG1 1 
ATOM   6917 C CG2 . VAL B 1 388 ? 78.703  116.729 135.532 1.00 102.62 ? 388 VAL B CG2 1 
ATOM   6918 N N   . PRO B 1 389 ? 83.207  118.644 135.418 1.00 91.73  ? 389 PRO B N   1 
ATOM   6919 C CA  . PRO B 1 389 ? 84.292  119.339 134.690 1.00 91.73  ? 389 PRO B CA  1 
ATOM   6920 C C   . PRO B 1 389 ? 84.660  118.623 133.396 1.00 91.73  ? 389 PRO B C   1 
ATOM   6921 O O   . PRO B 1 389 ? 85.673  117.923 133.283 1.00 91.73  ? 389 PRO B O   1 
ATOM   6922 C CB  . PRO B 1 389 ? 85.435  119.338 135.716 1.00 91.73  ? 389 PRO B CB  1 
ATOM   6923 C CG  . PRO B 1 389 ? 84.844  118.846 137.017 1.00 91.73  ? 389 PRO B CG  1 
ATOM   6924 C CD  . PRO B 1 389 ? 83.697  117.985 136.635 1.00 91.73  ? 389 PRO B CD  1 
ATOM   6925 N N   . ILE B 1 390 ? 83.814  118.797 132.380 1.00 82.21  ? 390 ILE B N   1 
ATOM   6926 C CA  . ILE B 1 390 ? 84.080  118.183 131.088 1.00 82.21  ? 390 ILE B CA  1 
ATOM   6927 C C   . ILE B 1 390 ? 85.206  118.931 130.385 1.00 82.21  ? 390 ILE B C   1 
ATOM   6928 O O   . ILE B 1 390 ? 85.395  120.144 130.564 1.00 82.21  ? 390 ILE B O   1 
ATOM   6929 C CB  . ILE B 1 390 ? 82.807  118.143 130.222 1.00 82.21  ? 390 ILE B CB  1 
ATOM   6930 C CG1 . ILE B 1 390 ? 82.375  119.554 129.818 1.00 82.21  ? 390 ILE B CG1 1 
ATOM   6931 C CG2 . ILE B 1 390 ? 81.685  117.432 130.960 1.00 82.21  ? 390 ILE B CG2 1 
ATOM   6932 C CD1 . ILE B 1 390 ? 81.180  119.587 128.891 1.00 82.21  ? 390 ILE B CD1 1 
ATOM   6933 N N   . ALA B 1 391 ? 85.976  118.195 129.588 1.00 60.33  ? 391 ALA B N   1 
ATOM   6934 C CA  . ALA B 1 391 ? 87.088  118.756 128.839 1.00 60.33  ? 391 ALA B CA  1 
ATOM   6935 C C   . ALA B 1 391 ? 87.149  118.090 127.474 1.00 60.33  ? 391 ALA B C   1 
ATOM   6936 O O   . ALA B 1 391 ? 86.646  116.981 127.279 1.00 60.33  ? 391 ALA B O   1 
ATOM   6937 C CB  . ALA B 1 391 ? 88.419  118.578 129.579 1.00 60.33  ? 391 ALA B CB  1 
ATOM   6938 N N   . LEU B 1 392 ? 87.766  118.791 126.520 1.00 44.53  ? 392 LEU B N   1 
ATOM   6939 C CA  . LEU B 1 392 ? 87.899  118.243 125.174 1.00 44.53  ? 392 LEU B CA  1 
ATOM   6940 C C   . LEU B 1 392 ? 88.785  117.004 125.167 1.00 44.53  ? 392 LEU B C   1 
ATOM   6941 O O   . LEU B 1 392 ? 88.501  116.034 124.455 1.00 44.53  ? 392 LEU B O   1 
ATOM   6942 C CB  . LEU B 1 392 ? 88.449  119.306 124.227 1.00 44.53  ? 392 LEU B CB  1 
ATOM   6943 C CG  . LEU B 1 392 ? 88.174  119.089 122.738 1.00 44.53  ? 392 LEU B CG  1 
ATOM   6944 C CD1 . LEU B 1 392 ? 86.745  118.622 122.517 1.00 44.53  ? 392 LEU B CD1 1 
ATOM   6945 C CD2 . LEU B 1 392 ? 88.449  120.360 121.952 1.00 44.53  ? 392 LEU B CD2 1 
ATOM   6946 N N   . GLY B 1 393 ? 89.853  117.013 125.953 1.00 42.49  ? 393 GLY B N   1 
ATOM   6947 C CA  . GLY B 1 393 ? 90.759  115.888 126.026 1.00 42.49  ? 393 GLY B CA  1 
ATOM   6948 C C   . GLY B 1 393 ? 91.990  116.082 125.155 1.00 42.49  ? 393 GLY B C   1 
ATOM   6949 O O   . GLY B 1 393 ? 92.007  116.865 124.205 1.00 42.49  ? 393 GLY B O   1 
ATOM   6950 N N   . GLY B 1 394 ? 93.046  115.343 125.499 1.00 39.63  ? 394 GLY B N   1 
ATOM   6951 C CA  . GLY B 1 394 ? 94.294  115.469 124.763 1.00 39.63  ? 394 GLY B CA  1 
ATOM   6952 C C   . GLY B 1 394 ? 94.211  114.895 123.361 1.00 39.63  ? 394 GLY B C   1 
ATOM   6953 O O   . GLY B 1 394 ? 94.562  115.562 122.383 1.00 39.63  ? 394 GLY B O   1 
ATOM   6954 N N   . GLY B 1 395 ? 93.754  113.648 123.244 1.00 35.12  ? 395 GLY B N   1 
ATOM   6955 C CA  . GLY B 1 395 ? 93.701  113.009 121.939 1.00 35.12  ? 395 GLY B CA  1 
ATOM   6956 C C   . GLY B 1 395 ? 92.677  113.628 121.006 1.00 35.12  ? 395 GLY B C   1 
ATOM   6957 O O   . GLY B 1 395 ? 92.915  113.745 119.802 1.00 35.12  ? 395 GLY B O   1 
ATOM   6958 N N   . THR B 1 396 ? 91.523  114.027 121.547 1.00 35.33  ? 396 THR B N   1 
ATOM   6959 C CA  . THR B 1 396 ? 90.442  114.532 120.705 1.00 35.33  ? 396 THR B CA  1 
ATOM   6960 C C   . THR B 1 396 ? 90.820  115.846 120.031 1.00 35.33  ? 396 THR B C   1 
ATOM   6961 O O   . THR B 1 396 ? 90.461  116.080 118.871 1.00 35.33  ? 396 THR B O   1 
ATOM   6962 C CB  . THR B 1 396 ? 89.170  114.702 121.534 1.00 35.33  ? 396 THR B CB  1 
ATOM   6963 O OG1 . THR B 1 396 ? 88.994  113.559 122.379 1.00 35.33  ? 396 THR B OG1 1 
ATOM   6964 C CG2 . THR B 1 396 ? 87.961  114.845 120.627 1.00 35.33  ? 396 THR B CG2 1 
ATOM   6965 N N   . ALA B 1 397 ? 91.535  116.721 120.742 1.00 34.03  ? 397 ALA B N   1 
ATOM   6966 C CA  . ALA B 1 397 ? 91.930  117.999 120.159 1.00 34.03  ? 397 ALA B CA  1 
ATOM   6967 C C   . ALA B 1 397 ? 92.940  117.820 119.032 1.00 34.03  ? 397 ALA B C   1 
ATOM   6968 O O   . ALA B 1 397 ? 93.020  118.664 118.131 1.00 34.03  ? 397 ALA B O   1 
ATOM   6969 C CB  . ALA B 1 397 ? 92.499  118.916 121.239 1.00 34.03  ? 397 ALA B CB  1 
ATOM   6970 N N   . SER B 1 398 ? 93.717  116.734 119.069 1.00 30.41  ? 398 SER B N   1 
ATOM   6971 C CA  . SER B 1 398 ? 94.697  116.488 118.016 1.00 30.41  ? 398 SER B CA  1 
ATOM   6972 C C   . SER B 1 398 ? 94.018  116.243 116.676 1.00 30.41  ? 398 SER B C   1 
ATOM   6973 O O   . SER B 1 398 ? 94.536  116.647 115.628 1.00 30.41  ? 398 SER B O   1 
ATOM   6974 C CB  . SER B 1 398 ? 95.584  115.303 118.394 1.00 30.41  ? 398 SER B CB  1 
ATOM   6975 O OG  . SER B 1 398 ? 96.449  114.961 117.327 1.00 30.41  ? 398 SER B OG  1 
ATOM   6976 N N   . LEU B 1 399 ? 92.862  115.576 116.687 1.00 31.56  ? 399 LEU B N   1 
ATOM   6977 C CA  . LEU B 1 399 ? 92.109  115.362 115.454 1.00 31.56  ? 399 LEU B CA  1 
ATOM   6978 C C   . LEU B 1 399 ? 91.686  116.686 114.831 1.00 31.56  ? 399 LEU B C   1 
ATOM   6979 O O   . LEU B 1 399 ? 91.825  116.890 113.620 1.00 31.56  ? 399 LEU B O   1 
ATOM   6980 C CB  . LEU B 1 399 ? 90.889  114.487 115.737 1.00 31.56  ? 399 LEU B CB  1 
ATOM   6981 C CG  . LEU B 1 399 ? 90.051  114.053 114.536 1.00 31.56  ? 399 LEU B CG  1 
ATOM   6982 C CD1 . LEU B 1 399 ? 90.667  112.840 113.869 1.00 31.56  ? 399 LEU B CD1 1 
ATOM   6983 C CD2 . LEU B 1 399 ? 88.627  113.762 114.966 1.00 31.56  ? 399 LEU B CD2 1 
ATOM   6984 N N   . ILE B 1 400 ? 91.178  117.606 115.655 1.00 31.34  ? 400 ILE B N   1 
ATOM   6985 C CA  . ILE B 1 400 ? 90.763  118.913 115.156 1.00 31.34  ? 400 ILE B CA  1 
ATOM   6986 C C   . ILE B 1 400 ? 91.965  119.696 114.642 1.00 31.34  ? 400 ILE B C   1 
ATOM   6987 O O   . ILE B 1 400 ? 91.886  120.375 113.610 1.00 31.34  ? 400 ILE B O   1 
ATOM   6988 C CB  . ILE B 1 400 ? 90.009  119.687 116.252 1.00 31.34  ? 400 ILE B CB  1 
ATOM   6989 C CG1 . ILE B 1 400 ? 88.860  118.842 116.801 1.00 31.34  ? 400 ILE B CG1 1 
ATOM   6990 C CG2 . ILE B 1 400 ? 89.486  121.006 115.713 1.00 31.34  ? 400 ILE B CG2 1 
ATOM   6991 C CD1 . ILE B 1 400 ? 88.071  119.524 117.894 1.00 31.34  ? 400 ILE B CD1 1 
ATOM   6992 N N   . VAL B 1 401 ? 93.092  119.620 115.356 1.00 32.55  ? 401 VAL B N   1 
ATOM   6993 C CA  . VAL B 1 401 ? 94.295  120.334 114.931 1.00 32.55  ? 401 VAL B CA  1 
ATOM   6994 C C   . VAL B 1 401 ? 94.774  119.813 113.580 1.00 32.55  ? 401 VAL B C   1 
ATOM   6995 O O   . VAL B 1 401 ? 95.114  120.590 112.681 1.00 32.55  ? 401 VAL B O   1 
ATOM   6996 C CB  . VAL B 1 401 ? 95.391  120.226 116.004 1.00 32.55  ? 401 VAL B CB  1 
ATOM   6997 C CG1 . VAL B 1 401 ? 96.755  120.554 115.417 1.00 32.55  ? 401 VAL B CG1 1 
ATOM   6998 C CG2 . VAL B 1 401 ? 95.079  121.154 117.163 1.00 32.55  ? 401 VAL B CG2 1 
ATOM   6999 N N   . GLY B 1 402 ? 94.792  118.489 113.414 1.00 33.96  ? 402 GLY B N   1 
ATOM   7000 C CA  . GLY B 1 402 ? 95.191  117.918 112.138 1.00 33.96  ? 402 GLY B CA  1 
ATOM   7001 C C   . GLY B 1 402 ? 94.241  118.278 111.012 1.00 33.96  ? 402 GLY B C   1 
ATOM   7002 O O   . GLY B 1 402 ? 94.673  118.573 109.895 1.00 33.96  ? 402 GLY B O   1 
ATOM   7003 N N   . LEU B 1 403 ? 92.935  118.264 111.295 1.00 37.11  ? 403 LEU B N   1 
ATOM   7004 C CA  . LEU B 1 403 ? 91.944  118.655 110.296 1.00 37.11  ? 403 LEU B CA  1 
ATOM   7005 C C   . LEU B 1 403 ? 92.172  120.090 109.833 1.00 37.11  ? 403 LEU B C   1 
ATOM   7006 O O   . LEU B 1 403 ? 92.215  120.372 108.627 1.00 37.11  ? 403 LEU B O   1 
ATOM   7007 C CB  . LEU B 1 403 ? 90.540  118.502 110.882 1.00 37.11  ? 403 LEU B CB  1 
ATOM   7008 C CG  . LEU B 1 403 ? 89.408  117.979 110.001 1.00 37.11  ? 403 LEU B CG  1 
ATOM   7009 C CD1 . LEU B 1 403 ? 89.746  116.599 109.477 1.00 37.11  ? 403 LEU B CD1 1 
ATOM   7010 C CD2 . LEU B 1 403 ? 88.099  117.955 110.771 1.00 37.11  ? 403 LEU B CD2 1 
ATOM   7011 N N   . VAL B 1 404 ? 92.332  121.007 110.791 1.00 38.23  ? 404 VAL B N   1 
ATOM   7012 C CA  . VAL B 1 404 ? 92.528  122.417 110.463 1.00 38.23  ? 404 VAL B CA  1 
ATOM   7013 C C   . VAL B 1 404 ? 93.828  122.613 109.697 1.00 38.23  ? 404 VAL B C   1 
ATOM   7014 O O   . VAL B 1 404 ? 93.879  123.370 108.719 1.00 38.23  ? 404 VAL B O   1 
ATOM   7015 C CB  . VAL B 1 404 ? 92.483  123.271 111.744 1.00 38.23  ? 404 VAL B CB  1 
ATOM   7016 C CG1 . VAL B 1 404 ? 92.985  124.679 111.474 1.00 38.23  ? 404 VAL B CG1 1 
ATOM   7017 C CG2 . VAL B 1 404 ? 91.071  123.307 112.301 1.00 38.23  ? 404 VAL B CG2 1 
ATOM   7018 N N   . GLN B 1 405 ? 94.899  121.939 110.124 1.00 44.30  ? 405 GLN B N   1 
ATOM   7019 C CA  . GLN B 1 405 ? 96.183  122.088 109.448 1.00 44.30  ? 405 GLN B CA  1 
ATOM   7020 C C   . GLN B 1 405 ? 96.120  121.585 108.013 1.00 44.30  ? 405 GLN B C   1 
ATOM   7021 O O   . GLN B 1 405 ? 96.639  122.237 107.101 1.00 44.30  ? 405 GLN B O   1 
ATOM   7022 C CB  . GLN B 1 405 ? 97.278  121.359 110.224 1.00 44.30  ? 405 GLN B CB  1 
ATOM   7023 C CG  . GLN B 1 405 ? 98.272  122.287 110.900 1.00 44.30  ? 405 GLN B CG  1 
ATOM   7024 C CD  . GLN B 1 405 ? 99.561  121.587 111.272 1.00 44.30  ? 405 GLN B CD  1 
ATOM   7025 O OE1 . GLN B 1 405 ? 100.257 121.045 110.414 1.00 44.30  ? 405 GLN B OE1 1 
ATOM   7026 N NE2 . GLN B 1 405 ? 99.885  121.591 112.560 1.00 44.30  ? 405 GLN B NE2 1 
ATOM   7027 N N   . SER B 1 406 ? 95.482  120.433 107.789 1.00 46.26  ? 406 SER B N   1 
ATOM   7028 C CA  . SER B 1 406 ? 95.357  119.918 106.428 1.00 46.26  ? 406 SER B CA  1 
ATOM   7029 C C   . SER B 1 406 ? 94.527  120.850 105.555 1.00 46.26  ? 406 SER B C   1 
ATOM   7030 O O   . SER B 1 406 ? 94.901  121.139 104.410 1.00 46.26  ? 406 SER B O   1 
ATOM   7031 C CB  . SER B 1 406 ? 94.746  118.519 106.447 1.00 46.26  ? 406 SER B CB  1 
ATOM   7032 O OG  . SER B 1 406 ? 94.407  118.103 105.136 1.00 46.26  ? 406 SER B OG  1 
ATOM   7033 N N   . ILE B 1 407 ? 93.403  121.345 106.085 1.00 52.80  ? 407 ILE B N   1 
ATOM   7034 C CA  . ILE B 1 407 ? 92.543  122.232 105.305 1.00 52.80  ? 407 ILE B CA  1 
ATOM   7035 C C   . ILE B 1 407 ? 93.277  123.522 104.954 1.00 52.80  ? 407 ILE B C   1 
ATOM   7036 O O   . ILE B 1 407 ? 93.207  124.004 103.817 1.00 52.80  ? 407 ILE B O   1 
ATOM   7037 C CB  . ILE B 1 407 ? 91.232  122.507 106.065 1.00 52.80  ? 407 ILE B CB  1 
ATOM   7038 C CG1 . ILE B 1 407 ? 90.328  121.274 106.022 1.00 52.80  ? 407 ILE B CG1 1 
ATOM   7039 C CG2 . ILE B 1 407 ? 90.513  123.717 105.492 1.00 52.80  ? 407 ILE B CG2 1 
ATOM   7040 C CD1 . ILE B 1 407 ? 88.975  121.485 106.667 1.00 52.80  ? 407 ILE B CD1 1 
ATOM   7041 N N   . TYR B 1 408 ? 94.005  124.092 105.915 1.00 62.17  ? 408 TYR B N   1 
ATOM   7042 C CA  . TYR B 1 408 ? 94.708  125.345 105.669 1.00 62.17  ? 408 TYR B CA  1 
ATOM   7043 C C   . TYR B 1 408 ? 95.895  125.152 104.730 1.00 62.17  ? 408 TYR B C   1 
ATOM   7044 O O   . TYR B 1 408 ? 96.182  126.033 103.910 1.00 62.17  ? 408 TYR B O   1 
ATOM   7045 C CB  . TYR B 1 408 ? 95.144  125.952 107.003 1.00 62.17  ? 408 TYR B CB  1 
ATOM   7046 C CG  . TYR B 1 408 ? 96.210  127.020 106.917 1.00 62.17  ? 408 TYR B CG  1 
ATOM   7047 C CD1 . TYR B 1 408 ? 95.990  128.197 106.215 1.00 62.17  ? 408 TYR B CD1 1 
ATOM   7048 C CD2 . TYR B 1 408 ? 97.428  126.861 107.565 1.00 62.17  ? 408 TYR B CD2 1 
ATOM   7049 C CE1 . TYR B 1 408 ? 96.961  129.178 106.144 1.00 62.17  ? 408 TYR B CE1 1 
ATOM   7050 C CE2 . TYR B 1 408 ? 98.402  127.835 107.503 1.00 62.17  ? 408 TYR B CE2 1 
ATOM   7051 C CZ  . TYR B 1 408 ? 98.166  128.990 106.790 1.00 62.17  ? 408 TYR B CZ  1 
ATOM   7052 O OH  . TYR B 1 408 ? 99.137  129.962 106.726 1.00 62.17  ? 408 TYR B OH  1 
ATOM   7053 N N   . ARG B 1 409 ? 96.587  124.011 104.819 1.00 64.03  ? 409 ARG B N   1 
ATOM   7054 C CA  . ARG B 1 409 ? 97.700  123.750 103.912 1.00 64.03  ? 409 ARG B CA  1 
ATOM   7055 C C   . ARG B 1 409 ? 97.214  123.473 102.495 1.00 64.03  ? 409 ARG B C   1 
ATOM   7056 O O   . ARG B 1 409 ? 97.945  123.731 101.532 1.00 64.03  ? 409 ARG B O   1 
ATOM   7057 C CB  . ARG B 1 409 ? 98.534  122.574 104.419 1.00 64.03  ? 409 ARG B CB  1 
ATOM   7058 C CG  . ARG B 1 409 ? 99.810  122.335 103.626 1.00 64.03  ? 409 ARG B CG  1 
ATOM   7059 C CD  . ARG B 1 409 ? 100.293 120.895 103.752 1.00 64.03  ? 409 ARG B CD  1 
ATOM   7060 N NE  . ARG B 1 409 ? 99.355  119.912 103.216 1.00 64.03  ? 409 ARG B NE  1 
ATOM   7061 C CZ  . ARG B 1 409 ? 98.922  119.854 101.961 1.00 64.03  ? 409 ARG B CZ  1 
ATOM   7062 N NH1 . ARG B 1 409 ? 99.374  120.676 101.027 1.00 64.03  ? 409 ARG B NH1 1 
ATOM   7063 N NH2 . ARG B 1 409 ? 98.024  118.930 101.628 1.00 64.03  ? 409 ARG B NH2 1 
ATOM   7064 N N   . ASP B 1 410 ? 95.999  122.936 102.348 1.00 69.74  ? 410 ASP B N   1 
ATOM   7065 C CA  . ASP B 1 410 ? 95.447  122.723 101.014 1.00 69.74  ? 410 ASP B CA  1 
ATOM   7066 C C   . ASP B 1 410 ? 95.332  124.052 100.273 1.00 69.74  ? 410 ASP B C   1 
ATOM   7067 O O   . ASP B 1 410 ? 95.714  124.155 99.101  1.00 69.74  ? 410 ASP B O   1 
ATOM   7068 C CB  . ASP B 1 410 ? 94.087  122.020 101.137 1.00 69.74  ? 410 ASP B CB  1 
ATOM   7069 C CG  . ASP B 1 410 ? 93.267  122.016 99.839  1.00 69.74  ? 410 ASP B CG  1 
ATOM   7070 O OD1 . ASP B 1 410 ? 93.803  122.244 98.735  1.00 69.74  ? 410 ASP B OD1 1 
ATOM   7071 O OD2 . ASP B 1 410 ? 92.045  121.776 99.937  1.00 69.74  ? 410 ASP B OD2 1 
ATOM   7072 N N   . LYS B 1 411 ? 94.845  125.091 100.953 1.00 77.01  ? 411 LYS B N   1 
ATOM   7073 C CA  . LYS B 1 411 ? 94.710  126.402 100.326 1.00 77.01  ? 411 LYS B CA  1 
ATOM   7074 C C   . LYS B 1 411 ? 96.058  127.110 100.219 1.00 77.01  ? 411 LYS B C   1 
ATOM   7075 O O   . LYS B 1 411 ? 96.504  127.452 99.118  1.00 77.01  ? 411 LYS B O   1 
ATOM   7076 C CB  . LYS B 1 411 ? 93.707  127.255 101.106 1.00 77.01  ? 411 LYS B CB  1 
ATOM   7077 C CG  . LYS B 1 411 ? 92.296  126.689 101.104 1.00 77.01  ? 411 LYS B CG  1 
ATOM   7078 C CD  . LYS B 1 411 ? 91.395  127.429 102.076 1.00 77.01  ? 411 LYS B CD  1 
ATOM   7079 C CE  . LYS B 1 411 ? 90.102  126.665 102.310 1.00 77.01  ? 411 LYS B CE  1 
ATOM   7080 N NZ  . LYS B 1 411 ? 88.917  127.565 102.340 1.00 77.01  ? 411 LYS B NZ  1 
ATOM   7081 N N   . HIS B 1 412 ? 96.722  127.339 101.350 1.00 87.83  ? 412 HIS B N   1 
ATOM   7082 C CA  . HIS B 1 412 ? 98.010  128.025 101.357 1.00 87.83  ? 412 HIS B CA  1 
ATOM   7083 C C   . HIS B 1 412 ? 99.131  126.994 101.270 1.00 87.83  ? 412 HIS B C   1 
ATOM   7084 O O   . HIS B 1 412 ? 99.276  126.151 102.160 1.00 87.83  ? 412 HIS B O   1 
ATOM   7085 C CB  . HIS B 1 412 ? 98.159  128.888 102.608 1.00 87.83  ? 412 HIS B CB  1 
ATOM   7086 C CG  . HIS B 1 412 ? 97.632  130.278 102.444 1.00 87.83  ? 412 HIS B CG  1 
ATOM   7087 N ND1 . HIS B 1 412 ? 96.336  130.541 102.057 1.00 87.83  ? 412 HIS B ND1 1 
ATOM   7088 C CD2 . HIS B 1 412 ? 98.227  131.484 102.608 1.00 87.83  ? 412 HIS B CD2 1 
ATOM   7089 C CE1 . HIS B 1 412 ? 96.153  131.848 101.992 1.00 87.83  ? 412 HIS B CE1 1 
ATOM   7090 N NE2 . HIS B 1 412 ? 97.286  132.443 102.323 1.00 87.83  ? 412 HIS B NE2 1 
ATOM   7091 N N   . ALA B 1 413 ? 99.929  127.077 100.207 1.00 104.58 ? 413 ALA B N   1 
ATOM   7092 C CA  . ALA B 1 413 ? 100.944 126.078 99.902  1.00 104.58 ? 413 ALA B CA  1 
ATOM   7093 C C   . ALA B 1 413 ? 102.334 126.467 100.387 1.00 104.58 ? 413 ALA B C   1 
ATOM   7094 O O   . ALA B 1 413 ? 103.315 125.836 99.982  1.00 104.58 ? 413 ALA B O   1 
ATOM   7095 C CB  . ALA B 1 413 ? 100.976 125.806 98.397  1.00 104.58 ? 413 ALA B CB  1 
ATOM   7096 N N   . HIS B 1 414 ? 102.445 127.498 101.229 1.00 113.16 ? 414 HIS B N   1 
ATOM   7097 C CA  . HIS B 1 414 ? 103.747 127.867 101.776 1.00 113.16 ? 414 HIS B CA  1 
ATOM   7098 C C   . HIS B 1 414 ? 104.321 126.746 102.634 1.00 113.16 ? 414 HIS B C   1 
ATOM   7099 O O   . HIS B 1 414 ? 105.518 126.443 102.558 1.00 113.16 ? 414 HIS B O   1 
ATOM   7100 C CB  . HIS B 1 414 ? 103.644 129.160 102.591 1.00 113.16 ? 414 HIS B CB  1 
ATOM   7101 C CG  . HIS B 1 414 ? 102.933 130.276 101.888 1.00 113.16 ? 414 HIS B CG  1 
ATOM   7102 N ND1 . HIS B 1 414 ? 101.586 130.241 101.598 1.00 113.16 ? 414 HIS B ND1 1 
ATOM   7103 C CD2 . HIS B 1 414 ? 103.387 131.462 101.419 1.00 113.16 ? 414 HIS B CD2 1 
ATOM   7104 C CE1 . HIS B 1 414 ? 101.241 131.357 100.980 1.00 113.16 ? 414 HIS B CE1 1 
ATOM   7105 N NE2 . HIS B 1 414 ? 102.315 132.115 100.859 1.00 113.16 ? 414 HIS B NE2 1 
ATOM   7106 N N   . MET B 1 415 ? 103.484 126.121 103.457 1.00 96.71  ? 415 MET B N   1 
ATOM   7107 C CA  . MET B 1 415 ? 103.915 125.012 104.292 1.00 96.71  ? 415 MET B CA  1 
ATOM   7108 C C   . MET B 1 415 ? 104.031 123.734 103.472 1.00 96.71  ? 415 MET B C   1 
ATOM   7109 O O   . MET B 1 415 ? 103.286 123.514 102.512 1.00 96.71  ? 415 MET B O   1 
ATOM   7110 C CB  . MET B 1 415 ? 102.942 124.803 105.452 1.00 96.71  ? 415 MET B CB  1 
ATOM   7111 C CG  . MET B 1 415 ? 102.932 125.933 106.470 1.00 96.71  ? 415 MET B CG  1 
ATOM   7112 S SD  . MET B 1 415 ? 102.660 127.558 105.737 1.00 96.71  ? 415 MET B SD  1 
ATOM   7113 C CE  . MET B 1 415 ? 100.980 127.394 105.138 1.00 96.71  ? 415 MET B CE  1 
ATOM   7114 N N   . ASP B 1 416 ? 104.979 122.888 103.861 1.00 90.54  ? 416 ASP B N   1 
ATOM   7115 C CA  . ASP B 1 416 ? 105.210 121.631 103.170 1.00 90.54  ? 416 ASP B CA  1 
ATOM   7116 C C   . ASP B 1 416 ? 104.269 120.549 103.697 1.00 90.54  ? 416 ASP B C   1 
ATOM   7117 O O   . ASP B 1 416 ? 103.550 120.734 104.683 1.00 90.54  ? 416 ASP B O   1 
ATOM   7118 C CB  . ASP B 1 416 ? 106.668 121.208 103.321 1.00 90.54  ? 416 ASP B CB  1 
ATOM   7119 C CG  . ASP B 1 416 ? 107.628 122.361 103.107 1.00 90.54  ? 416 ASP B CG  1 
ATOM   7120 O OD1 . ASP B 1 416 ? 107.590 123.320 103.904 1.00 90.54  ? 416 ASP B OD1 1 
ATOM   7121 O OD2 . ASP B 1 416 ? 108.410 122.315 102.135 1.00 90.54  ? 416 ASP B OD2 1 
ATOM   7122 N N   . THR B 1 417 ? 104.282 119.400 103.026 1.00 79.04  ? 417 THR B N   1 
ATOM   7123 C CA  . THR B 1 417 ? 103.366 118.308 103.317 1.00 79.04  ? 417 THR B CA  1 
ATOM   7124 C C   . THR B 1 417 ? 104.115 117.129 103.927 1.00 79.04  ? 417 THR B C   1 
ATOM   7125 O O   . THR B 1 417 ? 105.252 116.838 103.545 1.00 79.04  ? 417 THR B O   1 
ATOM   7126 C CB  . THR B 1 417 ? 102.635 117.847 102.054 1.00 79.04  ? 417 THR B CB  1 
ATOM   7127 O OG1 . THR B 1 417 ? 103.465 116.932 101.330 1.00 79.04  ? 417 THR B OG1 1 
ATOM   7128 C CG2 . THR B 1 417 ? 102.316 119.036 101.165 1.00 79.04  ? 417 THR B CG2 1 
ATOM   7129 N N   . ILE B 1 418 ? 103.466 116.460 104.870 1.00 57.97  ? 418 ILE B N   1 
ATOM   7130 C CA  . ILE B 1 418 ? 104.057 115.294 105.538 1.00 57.97  ? 418 ILE B CA  1 
ATOM   7131 C C   . ILE B 1 418 ? 104.034 114.105 104.585 1.00 57.97  ? 418 ILE B C   1 
ATOM   7132 O O   . ILE B 1 418 ? 103.029 113.905 103.878 1.00 57.97  ? 418 ILE B O   1 
ATOM   7133 C CB  . ILE B 1 418 ? 103.298 114.990 106.837 1.00 57.97  ? 418 ILE B CB  1 
ATOM   7134 C CG1 . ILE B 1 418 ? 103.706 115.965 107.948 1.00 57.97  ? 418 ILE B CG1 1 
ATOM   7135 C CG2 . ILE B 1 418 ? 103.526 113.562 107.297 1.00 57.97  ? 418 ILE B CG2 1 
ATOM   7136 C CD1 . ILE B 1 418 ? 102.943 117.274 107.954 1.00 57.97  ? 418 ILE B CD1 1 
ATOM   7137 N N   . PRO B 1 419 ? 105.102 113.308 104.508 1.00 58.41  ? 419 PRO B N   1 
ATOM   7138 C CA  . PRO B 1 419 ? 105.095 112.139 103.618 1.00 58.41  ? 419 PRO B CA  1 
ATOM   7139 C C   . PRO B 1 419 ? 104.044 111.117 104.028 1.00 58.41  ? 419 PRO B C   1 
ATOM   7140 O O   . PRO B 1 419 ? 103.635 111.039 105.188 1.00 58.41  ? 419 PRO B O   1 
ATOM   7141 C CB  . PRO B 1 419 ? 106.511 111.574 103.766 1.00 58.41  ? 419 PRO B CB  1 
ATOM   7142 C CG  . PRO B 1 419 ? 107.332 112.738 104.204 1.00 58.41  ? 419 PRO B CG  1 
ATOM   7143 C CD  . PRO B 1 419 ? 106.432 113.542 105.093 1.00 58.41  ? 419 PRO B CD  1 
ATOM   7144 N N   . ASP B 1 420 ? 103.609 110.323 103.046 1.00 59.08  ? 420 ASP B N   1 
ATOM   7145 C CA  . ASP B 1 420 ? 102.450 109.456 103.236 1.00 59.08  ? 420 ASP B CA  1 
ATOM   7146 C C   . ASP B 1 420 ? 102.755 108.297 104.182 1.00 59.08  ? 420 ASP B C   1 
ATOM   7147 O O   . ASP B 1 420 ? 101.955 107.990 105.074 1.00 59.08  ? 420 ASP B O   1 
ATOM   7148 C CB  . ASP B 1 420 ? 101.965 108.936 101.883 1.00 59.08  ? 420 ASP B CB  1 
ATOM   7149 C CG  . ASP B 1 420 ? 100.564 108.362 101.946 1.00 59.08  ? 420 ASP B CG  1 
ATOM   7150 O OD1 . ASP B 1 420 ? 100.383 107.286 102.553 1.00 59.08  ? 420 ASP B OD1 1 
ATOM   7151 O OD2 . ASP B 1 420 ? 99.640  108.992 101.390 1.00 59.08  ? 420 ASP B OD2 1 
ATOM   7152 N N   . SER B 1 421 ? 103.900 107.633 103.997 1.00 53.48  ? 421 SER B N   1 
ATOM   7153 C CA  . SER B 1 421 ? 104.218 106.462 104.813 1.00 53.48  ? 421 SER B CA  1 
ATOM   7154 C C   . SER B 1 421 ? 104.423 106.829 106.278 1.00 53.48  ? 421 SER B C   1 
ATOM   7155 O O   . SER B 1 421 ? 104.206 105.994 107.169 1.00 53.48  ? 421 SER B O   1 
ATOM   7156 C CB  . SER B 1 421 ? 105.462 105.765 104.264 1.00 53.48  ? 421 SER B CB  1 
ATOM   7157 O OG  . SER B 1 421 ? 106.518 106.689 104.077 1.00 53.48  ? 421 SER B OG  1 
ATOM   7158 N N   . LEU B 1 422 ? 104.839 108.071 106.541 1.00 46.57  ? 422 LEU B N   1 
ATOM   7159 C CA  . LEU B 1 422 ? 105.011 108.531 107.914 1.00 46.57  ? 422 LEU B CA  1 
ATOM   7160 C C   . LEU B 1 422 ? 103.694 108.482 108.677 1.00 46.57  ? 422 LEU B C   1 
ATOM   7161 O O   . LEU B 1 422 ? 103.662 108.075 109.844 1.00 46.57  ? 422 LEU B O   1 
ATOM   7162 C CB  . LEU B 1 422 ? 105.582 109.948 107.916 1.00 46.57  ? 422 LEU B CB  1 
ATOM   7163 C CG  . LEU B 1 422 ? 106.064 110.500 109.255 1.00 46.57  ? 422 LEU B CG  1 
ATOM   7164 C CD1 . LEU B 1 422 ? 107.309 109.768 109.699 1.00 46.57  ? 422 LEU B CD1 1 
ATOM   7165 C CD2 . LEU B 1 422 ? 106.332 111.990 109.152 1.00 46.57  ? 422 LEU B CD2 1 
ATOM   7166 N N   . LEU B 1 423 ? 102.596 108.878 108.029 1.00 43.63  ? 423 LEU B N   1 
ATOM   7167 C CA  . LEU B 1 423 ? 101.292 108.854 108.682 1.00 43.63  ? 423 LEU B CA  1 
ATOM   7168 C C   . LEU B 1 423 ? 100.866 107.431 109.029 1.00 43.63  ? 423 LEU B C   1 
ATOM   7169 O O   . LEU B 1 423 ? 100.331 107.183 110.118 1.00 43.63  ? 423 LEU B O   1 
ATOM   7170 C CB  . LEU B 1 423 ? 100.252 109.518 107.782 1.00 43.63  ? 423 LEU B CB  1 
ATOM   7171 C CG  . LEU B 1 423 ? 100.392 111.023 107.567 1.00 43.63  ? 423 LEU B CG  1 
ATOM   7172 C CD1 . LEU B 1 423 ? 99.121  111.587 106.960 1.00 43.63  ? 423 LEU B CD1 1 
ATOM   7173 C CD2 . LEU B 1 423 ? 100.716 111.724 108.875 1.00 43.63  ? 423 LEU B CD2 1 
ATOM   7174 N N   . GLU B 1 424 ? 101.077 106.488 108.107 1.00 44.95  ? 424 GLU B N   1 
ATOM   7175 C CA  . GLU B 1 424 ? 100.695 105.102 108.355 1.00 44.95  ? 424 GLU B CA  1 
ATOM   7176 C C   . GLU B 1 424 ? 101.503 104.508 109.502 1.00 44.95  ? 424 GLU B C   1 
ATOM   7177 O O   . GLU B 1 424 ? 100.947 103.855 110.400 1.00 44.95  ? 424 GLU B O   1 
ATOM   7178 C CB  . GLU B 1 424 ? 100.871 104.277 107.081 1.00 44.95  ? 424 GLU B CB  1 
ATOM   7179 C CG  . GLU B 1 424 ? 100.363 102.851 107.193 1.00 44.95  ? 424 GLU B CG  1 
ATOM   7180 C CD  . GLU B 1 424 ? 100.479 102.087 105.889 1.00 44.95  ? 424 GLU B CD  1 
ATOM   7181 O OE1 . GLU B 1 424 ? 99.910  102.547 104.877 1.00 44.95  ? 424 GLU B OE1 1 
ATOM   7182 O OE2 . GLU B 1 424 ? 101.134 101.024 105.878 1.00 44.95  ? 424 GLU B OE2 1 
ATOM   7183 N N   . PHE B 1 425 ? 102.823 104.729 109.483 1.00 41.31  ? 425 PHE B N   1 
ATOM   7184 C CA  . PHE B 1 425 ? 103.665 104.319 110.604 1.00 41.31  ? 425 PHE B CA  1 
ATOM   7185 C C   . PHE B 1 425 ? 103.156 104.909 111.911 1.00 41.31  ? 425 PHE B C   1 
ATOM   7186 O O   . PHE B 1 425 ? 103.023 104.199 112.919 1.00 41.31  ? 425 PHE B O   1 
ATOM   7187 C CB  . PHE B 1 425 ? 105.111 104.747 110.349 1.00 41.31  ? 425 PHE B CB  1 
ATOM   7188 C CG  . PHE B 1 425 ? 105.943 104.863 111.597 1.00 41.31  ? 425 PHE B CG  1 
ATOM   7189 C CD1 . PHE B 1 425 ? 106.579 103.758 112.130 1.00 41.31  ? 425 PHE B CD1 1 
ATOM   7190 C CD2 . PHE B 1 425 ? 106.105 106.090 112.227 1.00 41.31  ? 425 PHE B CD2 1 
ATOM   7191 C CE1 . PHE B 1 425 ? 107.344 103.874 113.270 1.00 41.31  ? 425 PHE B CE1 1 
ATOM   7192 C CE2 . PHE B 1 425 ? 106.863 106.204 113.369 1.00 41.31  ? 425 PHE B CE2 1 
ATOM   7193 C CZ  . PHE B 1 425 ? 107.480 105.095 113.893 1.00 41.31  ? 425 PHE B CZ  1 
ATOM   7194 N N   . PHE B 1 426 ? 102.868 106.214 111.904 1.00 39.98  ? 426 PHE B N   1 
ATOM   7195 C CA  . PHE B 1 426 ? 102.368 106.907 113.084 1.00 39.98  ? 426 PHE B CA  1 
ATOM   7196 C C   . PHE B 1 426 ? 101.153 106.203 113.658 1.00 39.98  ? 426 PHE B C   1 
ATOM   7197 O O   . PHE B 1 426 ? 101.173 105.735 114.801 1.00 39.98  ? 426 PHE B O   1 
ATOM   7198 C CB  . PHE B 1 426 ? 102.016 108.349 112.726 1.00 39.98  ? 426 PHE B CB  1 
ATOM   7199 C CG  . PHE B 1 426 ? 103.133 109.317 112.934 1.00 39.98  ? 426 PHE B CG  1 
ATOM   7200 C CD1 . PHE B 1 426 ? 104.033 109.143 113.971 1.00 39.98  ? 426 PHE B CD1 1 
ATOM   7201 C CD2 . PHE B 1 426 ? 103.280 110.408 112.098 1.00 39.98  ? 426 PHE B CD2 1 
ATOM   7202 C CE1 . PHE B 1 426 ? 105.060 110.038 114.164 1.00 39.98  ? 426 PHE B CE1 1 
ATOM   7203 C CE2 . PHE B 1 426 ? 104.303 111.304 112.286 1.00 39.98  ? 426 PHE B CE2 1 
ATOM   7204 C CZ  . PHE B 1 426 ? 105.193 111.121 113.319 1.00 39.98  ? 426 PHE B CZ  1 
ATOM   7205 N N   . GLN B 1 427 ? 100.086 106.101 112.859 1.00 39.99  ? 427 GLN B N   1 
ATOM   7206 C CA  . GLN B 1 427 ? 98.836  105.563 113.386 1.00 39.99  ? 427 GLN B CA  1 
ATOM   7207 C C   . GLN B 1 427 ? 99.019  104.130 113.872 1.00 39.99  ? 427 GLN B C   1 
ATOM   7208 O O   . GLN B 1 427 ? 98.668  103.806 115.017 1.00 39.99  ? 427 GLN B O   1 
ATOM   7209 C CB  . GLN B 1 427 ? 97.715  105.657 112.344 1.00 39.99  ? 427 GLN B CB  1 
ATOM   7210 C CG  . GLN B 1 427 ? 98.045  105.183 110.948 1.00 39.99  ? 427 GLN B CG  1 
ATOM   7211 C CD  . GLN B 1 427 ? 96.973  105.568 109.948 1.00 39.99  ? 427 GLN B CD  1 
ATOM   7212 O OE1 . GLN B 1 427 ? 96.675  106.749 109.766 1.00 39.99  ? 427 GLN B OE1 1 
ATOM   7213 N NE2 . GLN B 1 427 ? 96.383  104.573 109.297 1.00 39.99  ? 427 GLN B NE2 1 
ATOM   7214 N N   . SER B 1 428 ? 99.638  103.279 113.045 1.00 37.01  ? 428 SER B N   1 
ATOM   7215 C CA  . SER B 1 428 ? 99.778  101.870 113.401 1.00 37.01  ? 428 SER B CA  1 
ATOM   7216 C C   . SER B 1 428 ? 100.565 101.698 114.697 1.00 37.01  ? 428 SER B C   1 
ATOM   7217 O O   . SER B 1 428 ? 100.038 101.185 115.697 1.00 37.01  ? 428 SER B O   1 
ATOM   7218 C CB  . SER B 1 428 ? 100.445 101.109 112.255 1.00 37.01  ? 428 SER B CB  1 
ATOM   7219 O OG  . SER B 1 428 ? 100.608 99.741  112.580 1.00 37.01  ? 428 SER B OG  1 
ATOM   7220 N N   . ILE B 1 429 ? 101.830 102.131 114.703 1.00 31.65  ? 429 ILE B N   1 
ATOM   7221 C CA  . ILE B 1 429 ? 102.668 101.844 115.861 1.00 31.65  ? 429 ILE B CA  1 
ATOM   7222 C C   . ILE B 1 429 ? 102.206 102.611 117.094 1.00 31.65  ? 429 ILE B C   1 
ATOM   7223 O O   . ILE B 1 429 ? 102.269 102.078 118.206 1.00 31.65  ? 429 ILE B O   1 
ATOM   7224 C CB  . ILE B 1 429 ? 104.155 102.079 115.531 1.00 31.65  ? 429 ILE B CB  1 
ATOM   7225 C CG1 . ILE B 1 429 ? 104.734 100.803 114.917 1.00 31.65  ? 429 ILE B CG1 1 
ATOM   7226 C CG2 . ILE B 1 429 ? 104.955 102.496 116.755 1.00 31.65  ? 429 ILE B CG2 1 
ATOM   7227 C CD1 . ILE B 1 429 ? 106.176 100.901 114.518 1.00 31.65  ? 429 ILE B CD1 1 
ATOM   7228 N N   . GLY B 1 430 ? 101.703 103.841 116.942 1.00 29.59  ? 430 GLY B N   1 
ATOM   7229 C CA  . GLY B 1 430 ? 101.217 104.562 118.106 1.00 29.59  ? 430 GLY B CA  1 
ATOM   7230 C C   . GLY B 1 430 ? 100.042 103.875 118.775 1.00 29.59  ? 430 GLY B C   1 
ATOM   7231 O O   . GLY B 1 430 ? 100.022 103.704 120.002 1.00 29.59  ? 430 GLY B O   1 
ATOM   7232 N N   . LEU B 1 431 ? 99.049  103.455 117.982 1.00 29.15  ? 431 LEU B N   1 
ATOM   7233 C CA  . LEU B 1 431 ? 97.900  102.780 118.573 1.00 29.15  ? 431 LEU B CA  1 
ATOM   7234 C C   . LEU B 1 431 ? 98.304  101.462 119.220 1.00 29.15  ? 431 LEU B C   1 
ATOM   7235 O O   . LEU B 1 431 ? 97.888  101.162 120.350 1.00 29.15  ? 431 LEU B O   1 
ATOM   7236 C CB  . LEU B 1 431 ? 96.820  102.554 117.517 1.00 29.15  ? 431 LEU B CB  1 
ATOM   7237 C CG  . LEU B 1 431 ? 95.559  101.867 118.037 1.00 29.15  ? 431 LEU B CG  1 
ATOM   7238 C CD1 . LEU B 1 431 ? 94.927  102.707 119.129 1.00 29.15  ? 431 LEU B CD1 1 
ATOM   7239 C CD2 . LEU B 1 431 ? 94.575  101.627 116.906 1.00 29.15  ? 431 LEU B CD2 1 
ATOM   7240 N N   . ASN B 1 432 ? 99.139  100.670 118.534 1.00 25.36  ? 432 ASN B N   1 
ATOM   7241 C CA  . ASN B 1 432 ? 99.543  99.392  119.114 1.00 25.36  ? 432 ASN B CA  1 
ATOM   7242 C C   . ASN B 1 432 ? 100.385 99.583  120.371 1.00 25.36  ? 432 ASN B C   1 
ATOM   7243 O O   . ASN B 1 432 ? 100.276 98.795  121.315 1.00 25.36  ? 432 ASN B O   1 
ATOM   7244 C CB  . ASN B 1 432 ? 100.285 98.539  118.087 1.00 25.36  ? 432 ASN B CB  1 
ATOM   7245 C CG  . ASN B 1 432 ? 99.382  98.062  116.966 1.00 25.36  ? 432 ASN B CG  1 
ATOM   7246 O OD1 . ASN B 1 432 ? 99.467  98.533  115.835 1.00 25.36  ? 432 ASN B OD1 1 
ATOM   7247 N ND2 . ASN B 1 432 ? 98.499  97.125  117.284 1.00 25.36  ? 432 ASN B ND2 1 
ATOM   7248 N N   . LEU B 1 433 ? 101.211 100.630 120.418 1.00 29.45  ? 433 LEU B N   1 
ATOM   7249 C CA  . LEU B 1 433 ? 102.028 100.876 121.602 1.00 29.45  ? 433 LEU B CA  1 
ATOM   7250 C C   . LEU B 1 433 ? 101.169 101.289 122.789 1.00 29.45  ? 433 LEU B C   1 
ATOM   7251 O O   . LEU B 1 433 ? 101.405 100.836 123.916 1.00 29.45  ? 433 LEU B O   1 
ATOM   7252 C CB  . LEU B 1 433 ? 103.084 101.940 121.297 1.00 29.45  ? 433 LEU B CB  1 
ATOM   7253 C CG  . LEU B 1 433 ? 104.410 101.914 122.062 1.00 29.45  ? 433 LEU B CG  1 
ATOM   7254 C CD1 . LEU B 1 433 ? 105.438 102.747 121.324 1.00 29.45  ? 433 LEU B CD1 1 
ATOM   7255 C CD2 . LEU B 1 433 ? 104.266 102.420 123.487 1.00 29.45  ? 433 LEU B CD2 1 
ATOM   7256 N N   . PHE B 1 434 ? 100.173 102.152 122.562 1.00 24.47  ? 434 PHE B N   1 
ATOM   7257 C CA  . PHE B 1 434 ? 99.276  102.523 123.655 1.00 24.47  ? 434 PHE B CA  1 
ATOM   7258 C C   . PHE B 1 434 ? 98.524  101.304 124.178 1.00 24.47  ? 434 PHE B C   1 
ATOM   7259 O O   . PHE B 1 434 ? 98.395  101.114 125.399 1.00 24.47  ? 434 PHE B O   1 
ATOM   7260 C CB  . PHE B 1 434 ? 98.308  103.612 123.187 1.00 24.47  ? 434 PHE B CB  1 
ATOM   7261 C CG  . PHE B 1 434 ? 97.375  104.113 124.260 1.00 24.47  ? 434 PHE B CG  1 
ATOM   7262 C CD1 . PHE B 1 434 ? 96.189  103.453 124.546 1.00 24.47  ? 434 PHE B CD1 1 
ATOM   7263 C CD2 . PHE B 1 434 ? 97.688  105.250 124.984 1.00 24.47  ? 434 PHE B CD2 1 
ATOM   7264 C CE1 . PHE B 1 434 ? 95.339  103.918 125.528 1.00 24.47  ? 434 PHE B CE1 1 
ATOM   7265 C CE2 . PHE B 1 434 ? 96.840  105.718 125.969 1.00 24.47  ? 434 PHE B CE2 1 
ATOM   7266 C CZ  . PHE B 1 434 ? 95.665  105.051 126.241 1.00 24.47  ? 434 PHE B CZ  1 
ATOM   7267 N N   . ILE B 1 435 ? 98.030  100.461 123.267 1.00 24.66  ? 435 ILE B N   1 
ATOM   7268 C CA  . ILE B 1 435 ? 97.299  99.267  123.683 1.00 24.66  ? 435 ILE B CA  1 
ATOM   7269 C C   . ILE B 1 435 ? 98.209  98.319  124.455 1.00 24.66  ? 435 ILE B C   1 
ATOM   7270 O O   . ILE B 1 435 ? 97.808  97.743  125.475 1.00 24.66  ? 435 ILE B O   1 
ATOM   7271 C CB  . ILE B 1 435 ? 96.663  98.586  122.458 1.00 24.66  ? 435 ILE B CB  1 
ATOM   7272 C CG1 . ILE B 1 435 ? 95.585  99.490  121.862 1.00 24.66  ? 435 ILE B CG1 1 
ATOM   7273 C CG2 . ILE B 1 435 ? 96.070  97.247  122.831 1.00 24.66  ? 435 ILE B CG2 1 
ATOM   7274 C CD1 . ILE B 1 435 ? 94.554  99.945  122.862 1.00 24.66  ? 435 ILE B CD1 1 
ATOM   7275 N N   . ALA B 1 436 ? 99.451  98.151  123.992 1.00 29.48  ? 436 ALA B N   1 
ATOM   7276 C CA  . ALA B 1 436 ? 100.402 97.289  124.687 1.00 29.48  ? 436 ALA B CA  1 
ATOM   7277 C C   . ALA B 1 436 ? 100.708 97.811  126.081 1.00 29.48  ? 436 ALA B C   1 
ATOM   7278 O O   . ALA B 1 436 ? 100.797 97.030  127.035 1.00 29.48  ? 436 ALA B O   1 
ATOM   7279 C CB  . ALA B 1 436 ? 101.691 97.162  123.876 1.00 29.48  ? 436 ALA B CB  1 
ATOM   7280 N N   . THR B 1 437 ? 100.884 99.126  126.219 1.00 22.07  ? 437 THR B N   1 
ATOM   7281 C CA  . THR B 1 437 ? 101.159 99.698  127.533 1.00 22.07  ? 437 THR B CA  1 
ATOM   7282 C C   . THR B 1 437 ? 99.995  99.464  128.491 1.00 22.07  ? 437 THR B C   1 
ATOM   7283 O O   . THR B 1 437 ? 100.200 99.040  129.637 1.00 22.07  ? 437 THR B O   1 
ATOM   7284 C CB  . THR B 1 437 ? 101.468 101.190 127.399 1.00 22.07  ? 437 THR B CB  1 
ATOM   7285 O OG1 . THR B 1 437 ? 102.838 101.361 127.015 1.00 22.07  ? 437 THR B OG1 1 
ATOM   7286 C CG2 . THR B 1 437 ? 101.225 101.921 128.711 1.00 22.07  ? 437 THR B CG2 1 
ATOM   7287 N N   . VAL B 1 438 ? 98.763  99.699  128.028 1.00 31.79  ? 438 VAL B N   1 
ATOM   7288 C CA  . VAL B 1 438 ? 97.602  99.506  128.897 1.00 31.79  ? 438 VAL B CA  1 
ATOM   7289 C C   . VAL B 1 438 ? 97.461  98.038  129.291 1.00 31.79  ? 438 VAL B C   1 
ATOM   7290 O O   . VAL B 1 438 ? 97.214  97.712  130.463 1.00 31.79  ? 438 VAL B O   1 
ATOM   7291 C CB  . VAL B 1 438 ? 96.329  100.042 128.215 1.00 31.79  ? 438 VAL B CB  1 
ATOM   7292 C CG1 . VAL B 1 438 ? 95.088  99.363  128.768 1.00 31.79  ? 438 VAL B CG1 1 
ATOM   7293 C CG2 . VAL B 1 438 ? 96.236  101.547 128.389 1.00 31.79  ? 438 VAL B CG2 1 
ATOM   7294 N N   . GLY B 1 439 ? 97.632  97.131  128.325 1.00 27.38  ? 439 GLY B N   1 
ATOM   7295 C CA  . GLY B 1 439 ? 97.509  95.714  128.623 1.00 27.38  ? 439 GLY B CA  1 
ATOM   7296 C C   . GLY B 1 439 ? 98.587  95.212  129.564 1.00 27.38  ? 439 GLY B C   1 
ATOM   7297 O O   . GLY B 1 439 ? 98.324  94.376  130.434 1.00 27.38  ? 439 GLY B O   1 
ATOM   7298 N N   . LEU B 1 440 ? 99.816  95.706  129.401 1.00 31.77  ? 440 LEU B N   1 
ATOM   7299 C CA  . LEU B 1 440 ? 100.887 95.349  130.322 1.00 31.77  ? 440 LEU B CA  1 
ATOM   7300 C C   . LEU B 1 440 ? 100.612 95.889  131.717 1.00 31.77  ? 440 LEU B C   1 
ATOM   7301 O O   . LEU B 1 440 ? 100.953 95.247  132.718 1.00 31.77  ? 440 LEU B O   1 
ATOM   7302 C CB  . LEU B 1 440 ? 102.223 95.873  129.797 1.00 31.77  ? 440 LEU B CB  1 
ATOM   7303 C CG  . LEU B 1 440 ? 102.906 95.018  128.732 1.00 31.77  ? 440 LEU B CG  1 
ATOM   7304 C CD1 . LEU B 1 440 ? 104.040 95.792  128.087 1.00 31.77  ? 440 LEU B CD1 1 
ATOM   7305 C CD2 . LEU B 1 440 ? 103.407 93.717  129.331 1.00 31.77  ? 440 LEU B CD2 1 
ATOM   7306 N N   . SER B 1 441 ? 100.005 97.075  131.803 1.00 34.82  ? 441 SER B N   1 
ATOM   7307 C CA  . SER B 1 441 ? 99.642  97.634  133.101 1.00 34.82  ? 441 SER B CA  1 
ATOM   7308 C C   . SER B 1 441 ? 98.617  96.758  133.812 1.00 34.82  ? 441 SER B C   1 
ATOM   7309 O O   . SER B 1 441 ? 98.854  96.281  134.927 1.00 34.82  ? 441 SER B O   1 
ATOM   7310 C CB  . SER B 1 441 ? 99.103  99.052  132.927 1.00 34.82  ? 441 SER B CB  1 
ATOM   7311 O OG  . SER B 1 441 ? 98.449  99.494  134.105 1.00 34.82  ? 441 SER B OG  1 
ATOM   7312 N N   . ALA B 1 442 ? 97.466  96.532  133.178 1.00 34.27  ? 442 ALA B N   1 
ATOM   7313 C CA  . ALA B 1 442 ? 96.366  95.817  133.832 1.00 34.27  ? 442 ALA B CA  1 
ATOM   7314 C C   . ALA B 1 442 ? 96.444  94.332  133.484 1.00 34.27  ? 442 ALA B C   1 
ATOM   7315 O O   . ALA B 1 442 ? 95.722  93.820  132.628 1.00 34.27  ? 442 ALA B O   1 
ATOM   7316 C CB  . ALA B 1 442 ? 95.025  96.418  133.433 1.00 34.27  ? 442 ALA B CB  1 
ATOM   7317 N N   . ALA B 1 443 ? 97.337  93.626  134.177 1.00 37.77  ? 443 ALA B N   1 
ATOM   7318 C CA  . ALA B 1 443 ? 97.522  92.208  133.895 1.00 37.77  ? 443 ALA B CA  1 
ATOM   7319 C C   . ALA B 1 443 ? 97.564  91.343  135.151 1.00 37.77  ? 443 ALA B C   1 
ATOM   7320 O O   . ALA B 1 443 ? 97.086  90.204  135.132 1.00 37.77  ? 443 ALA B O   1 
ATOM   7321 C CB  . ALA B 1 443 ? 98.798  92.001  133.080 1.00 37.77  ? 443 ALA B CB  1 
ATOM   7322 N N   . LYS B 1 444 ? 98.144  91.860  136.238 1.00 47.90  ? 444 LYS B N   1 
ATOM   7323 C CA  . LYS B 1 444 ? 98.292  91.055  137.450 1.00 47.90  ? 444 LYS B CA  1 
ATOM   7324 C C   . LYS B 1 444 ? 96.942  90.733  138.084 1.00 47.90  ? 444 LYS B C   1 
ATOM   7325 O O   . LYS B 1 444 ? 96.708  89.598  138.515 1.00 47.90  ? 444 LYS B O   1 
ATOM   7326 C CB  . LYS B 1 444 ? 99.200  91.768  138.453 1.00 47.90  ? 444 LYS B CB  1 
ATOM   7327 C CG  . LYS B 1 444 ? 100.643 91.291  138.431 1.00 47.90  ? 444 LYS B CG  1 
ATOM   7328 C CD  . LYS B 1 444 ? 100.736 89.817  138.790 1.00 47.90  ? 444 LYS B CD  1 
ATOM   7329 C CE  . LYS B 1 444 ? 102.144 89.432  139.210 1.00 47.90  ? 444 LYS B CE  1 
ATOM   7330 N NZ  . LYS B 1 444 ? 102.263 87.971  139.469 1.00 47.90  ? 444 LYS B NZ  1 
ATOM   7331 N N   . THR B 1 445 ? 96.045  91.712  138.145 1.00 53.38  ? 445 THR B N   1 
ATOM   7332 C CA  . THR B 1 445 ? 94.725  91.539  138.736 1.00 53.38  ? 445 THR B CA  1 
ATOM   7333 C C   . THR B 1 445 ? 93.669  91.134  137.712 1.00 53.38  ? 445 THR B C   1 
ATOM   7334 O O   . THR B 1 445 ? 92.475  91.140  138.032 1.00 53.38  ? 445 THR B O   1 
ATOM   7335 C CB  . THR B 1 445 ? 94.306  92.821  139.457 1.00 53.38  ? 445 THR B CB  1 
ATOM   7336 O OG1 . THR B 1 445 ? 94.276  93.906  138.526 1.00 53.38  ? 445 THR B OG1 1 
ATOM   7337 C CG2 . THR B 1 445 ? 95.289  93.150  140.568 1.00 53.38  ? 445 THR B CG2 1 
ATOM   7338 N N   . PHE B 1 446 ? 94.091  90.784  136.494 1.00 55.86  ? 446 PHE B N   1 
ATOM   7339 C CA  . PHE B 1 446 ? 93.162  90.349  135.455 1.00 55.86  ? 446 PHE B CA  1 
ATOM   7340 C C   . PHE B 1 446 ? 92.384  89.109  135.876 1.00 55.86  ? 446 PHE B C   1 
ATOM   7341 O O   . PHE B 1 446 ? 91.152  89.065  135.763 1.00 55.86  ? 446 PHE B O   1 
ATOM   7342 C CB  . PHE B 1 446 ? 93.938  90.086  134.165 1.00 55.86  ? 446 PHE B CB  1 
ATOM   7343 C CG  . PHE B 1 446 ? 93.203  89.237  133.172 1.00 55.86  ? 446 PHE B CG  1 
ATOM   7344 C CD1 . PHE B 1 446 ? 92.063  89.697  132.543 1.00 55.86  ? 446 PHE B CD1 1 
ATOM   7345 C CD2 . PHE B 1 446 ? 93.661  87.963  132.873 1.00 55.86  ? 446 PHE B CD2 1 
ATOM   7346 C CE1 . PHE B 1 446 ? 91.397  88.902  131.631 1.00 55.86  ? 446 PHE B CE1 1 
ATOM   7347 C CE2 . PHE B 1 446 ? 92.999  87.168  131.965 1.00 55.86  ? 446 PHE B CE2 1 
ATOM   7348 C CZ  . PHE B 1 446 ? 91.865  87.639  131.342 1.00 55.86  ? 446 PHE B CZ  1 
ATOM   7349 N N   . ILE B 1 447 ? 93.090  88.084  136.358 1.00 63.76  ? 447 ILE B N   1 
ATOM   7350 C CA  . ILE B 1 447 ? 92.413  86.852  136.745 1.00 63.76  ? 447 ILE B CA  1 
ATOM   7351 C C   . ILE B 1 447 ? 91.546  87.070  137.982 1.00 63.76  ? 447 ILE B C   1 
ATOM   7352 O O   . ILE B 1 447 ? 90.463  86.485  138.093 1.00 63.76  ? 447 ILE B O   1 
ATOM   7353 C CB  . ILE B 1 447 ? 93.435  85.711  136.930 1.00 63.76  ? 447 ILE B CB  1 
ATOM   7354 C CG1 . ILE B 1 447 ? 92.729  84.353  136.922 1.00 63.76  ? 447 ILE B CG1 1 
ATOM   7355 C CG2 . ILE B 1 447 ? 94.285  85.905  138.182 1.00 63.76  ? 447 ILE B CG2 1 
ATOM   7356 C CD1 . ILE B 1 447 ? 93.594  83.205  137.407 1.00 63.76  ? 447 ILE B CD1 1 
ATOM   7357 N N   . SER B 1 448 ? 91.978  87.927  138.911 1.00 66.06  ? 448 SER B N   1 
ATOM   7358 C CA  . SER B 1 448 ? 91.153  88.220  140.079 1.00 66.06  ? 448 SER B CA  1 
ATOM   7359 C C   . SER B 1 448 ? 89.863  88.923  139.680 1.00 66.06  ? 448 SER B C   1 
ATOM   7360 O O   . SER B 1 448 ? 88.787  88.602  140.200 1.00 66.06  ? 448 SER B O   1 
ATOM   7361 C CB  . SER B 1 448 ? 91.936  89.066  141.081 1.00 66.06  ? 448 SER B CB  1 
ATOM   7362 O OG  . SER B 1 448 ? 91.072  89.956  141.767 1.00 66.06  ? 448 SER B OG  1 
ATOM   7363 N N   . ALA B 1 449 ? 89.941  89.867  138.742 1.00 66.75  ? 449 ALA B N   1 
ATOM   7364 C CA  . ALA B 1 449 ? 88.730  90.547  138.309 1.00 66.75  ? 449 ALA B CA  1 
ATOM   7365 C C   . ALA B 1 449 ? 87.834  89.664  137.451 1.00 66.75  ? 449 ALA B C   1 
ATOM   7366 O O   . ALA B 1 449 ? 86.610  89.813  137.504 1.00 66.75  ? 449 ALA B O   1 
ATOM   7367 C CB  . ALA B 1 449 ? 89.080  91.822  137.545 1.00 66.75  ? 449 ALA B CB  1 
ATOM   7368 N N   . ILE B 1 450 ? 88.405  88.727  136.692 1.00 67.35  ? 450 ILE B N   1 
ATOM   7369 C CA  . ILE B 1 450 ? 87.571  87.795  135.940 1.00 67.35  ? 450 ILE B CA  1 
ATOM   7370 C C   . ILE B 1 450 ? 86.978  86.719  136.837 1.00 67.35  ? 450 ILE B C   1 
ATOM   7371 O O   . ILE B 1 450 ? 85.983  86.088  136.460 1.00 67.35  ? 450 ILE B O   1 
ATOM   7372 C CB  . ILE B 1 450 ? 88.354  87.161  134.776 1.00 67.35  ? 450 ILE B CB  1 
ATOM   7373 C CG1 . ILE B 1 450 ? 87.425  86.888  133.593 1.00 67.35  ? 450 ILE B CG1 1 
ATOM   7374 C CG2 . ILE B 1 450 ? 89.040  85.872  135.208 1.00 67.35  ? 450 ILE B CG2 1 
ATOM   7375 C CD1 . ILE B 1 450 ? 86.663  88.097  133.120 1.00 67.35  ? 450 ILE B CD1 1 
ATOM   7376 N N   . GLN B 1 451 ? 87.558  86.489  138.017 1.00 71.28  ? 451 GLN B N   1 
ATOM   7377 C CA  . GLN B 1 451 ? 86.875  85.676  139.017 1.00 71.28  ? 451 GLN B CA  1 
ATOM   7378 C C   . GLN B 1 451 ? 85.755  86.457  139.690 1.00 71.28  ? 451 GLN B C   1 
ATOM   7379 O O   . GLN B 1 451 ? 84.677  85.907  139.940 1.00 71.28  ? 451 GLN B O   1 
ATOM   7380 C CB  . GLN B 1 451 ? 87.861  85.162  140.067 1.00 71.28  ? 451 GLN B CB  1 
ATOM   7381 C CG  . GLN B 1 451 ? 88.872  84.163  139.544 1.00 71.28  ? 451 GLN B CG  1 
ATOM   7382 C CD  . GLN B 1 451 ? 88.271  82.788  139.341 1.00 71.28  ? 451 GLN B CD  1 
ATOM   7383 O OE1 . GLN B 1 451 ? 87.344  82.394  140.047 1.00 71.28  ? 451 GLN B OE1 1 
ATOM   7384 N NE2 . GLN B 1 451 ? 88.797  82.050  138.370 1.00 71.28  ? 451 GLN B NE2 1 
ATOM   7385 N N   . SER B 1 452 ? 85.992  87.736  139.995 1.00 71.63  ? 452 SER B N   1 
ATOM   7386 C CA  . SER B 1 452 ? 84.985  88.527  140.697 1.00 71.63  ? 452 SER B CA  1 
ATOM   7387 C C   . SER B 1 452 ? 83.757  88.762  139.824 1.00 71.63  ? 452 SER B C   1 
ATOM   7388 O O   . SER B 1 452 ? 82.622  88.520  140.250 1.00 71.63  ? 452 SER B O   1 
ATOM   7389 C CB  . SER B 1 452 ? 85.580  89.856  141.166 1.00 71.63  ? 452 SER B CB  1 
ATOM   7390 O OG  . SER B 1 452 ? 86.109  90.596  140.085 1.00 71.63  ? 452 SER B OG  1 
ATOM   7391 N N   . MET B 1 453 ? 83.958  89.238  138.588 1.00 73.69  ? 453 MET B N   1 
ATOM   7392 C CA  . MET B 1 453 ? 82.841  89.566  137.690 1.00 73.69  ? 453 MET B CA  1 
ATOM   7393 C C   . MET B 1 453 ? 83.052  88.855  136.354 1.00 73.69  ? 453 MET B C   1 
ATOM   7394 O O   . MET B 1 453 ? 83.670  89.398  135.436 1.00 73.69  ? 453 MET B O   1 
ATOM   7395 C CB  . MET B 1 453 ? 82.700  91.082  137.514 1.00 73.69  ? 453 MET B CB  1 
ATOM   7396 C CG  . MET B 1 453 ? 83.985  91.867  137.694 1.00 73.69  ? 453 MET B CG  1 
ATOM   7397 S SD  . MET B 1 453 ? 83.696  93.645  137.651 1.00 73.69  ? 453 MET B SD  1 
ATOM   7398 C CE  . MET B 1 453 ? 85.377  94.246  137.744 1.00 73.69  ? 453 MET B CE  1 
ATOM   7399 N N   . GLY B 1 454 ? 82.528  87.635  136.253 1.00 70.23  ? 454 GLY B N   1 
ATOM   7400 C CA  . GLY B 1 454 ? 82.695  86.822  135.065 1.00 70.23  ? 454 GLY B CA  1 
ATOM   7401 C C   . GLY B 1 454 ? 81.854  87.215  133.866 1.00 70.23  ? 454 GLY B C   1 
ATOM   7402 O O   . GLY B 1 454 ? 82.395  87.605  132.826 1.00 70.23  ? 454 GLY B O   1 
ATOM   7403 N N   . ILE B 1 455 ? 80.530  87.130  133.997 1.00 67.74  ? 455 ILE B N   1 
ATOM   7404 C CA  . ILE B 1 455 ? 79.628  87.250  132.858 1.00 67.74  ? 455 ILE B CA  1 
ATOM   7405 C C   . ILE B 1 455 ? 78.942  88.616  132.812 1.00 67.74  ? 455 ILE B C   1 
ATOM   7406 O O   . ILE B 1 455 ? 78.473  89.038  131.747 1.00 67.74  ? 455 ILE B O   1 
ATOM   7407 C CB  . ILE B 1 455 ? 78.619  86.082  132.882 1.00 67.74  ? 455 ILE B CB  1 
ATOM   7408 C CG1 . ILE B 1 455 ? 79.336  84.788  132.504 1.00 67.74  ? 455 ILE B CG1 1 
ATOM   7409 C CG2 . ILE B 1 455 ? 77.428  86.283  131.948 1.00 67.74  ? 455 ILE B CG2 1 
ATOM   7410 C CD1 . ILE B 1 455 ? 80.077  84.860  131.170 1.00 67.74  ? 455 ILE B CD1 1 
ATOM   7411 N N   . SER B 1 456 ? 78.994  89.377  133.904 1.00 65.39  ? 456 SER B N   1 
ATOM   7412 C CA  . SER B 1 456 ? 78.307  90.658  133.980 1.00 65.39  ? 456 SER B CA  1 
ATOM   7413 C C   . SER B 1 456 ? 79.168  91.809  133.470 1.00 65.39  ? 456 SER B C   1 
ATOM   7414 O O   . SER B 1 456 ? 78.835  92.976  133.703 1.00 65.39  ? 456 SER B O   1 
ATOM   7415 C CB  . SER B 1 456 ? 77.861  90.928  135.417 1.00 65.39  ? 456 SER B CB  1 
ATOM   7416 O OG  . SER B 1 456 ? 77.574  92.302  135.616 1.00 65.39  ? 456 SER B OG  1 
ATOM   7417 N N   . VAL B 1 457 ? 80.260  91.509  132.765 1.00 59.71  ? 457 VAL B N   1 
ATOM   7418 C CA  . VAL B 1 457 ? 81.128  92.550  132.226 1.00 59.71  ? 457 VAL B CA  1 
ATOM   7419 C C   . VAL B 1 457 ? 81.417  92.256  130.756 1.00 59.71  ? 457 VAL B C   1 
ATOM   7420 O O   . VAL B 1 457 ? 81.915  93.119  130.023 1.00 59.71  ? 457 VAL B O   1 
ATOM   7421 C CB  . VAL B 1 457 ? 82.418  92.664  133.065 1.00 59.71  ? 457 VAL B CB  1 
ATOM   7422 C CG1 . VAL B 1 457 ? 83.278  91.424  132.916 1.00 59.71  ? 457 VAL B CG1 1 
ATOM   7423 C CG2 . VAL B 1 457 ? 83.192  93.935  132.739 1.00 59.71  ? 457 VAL B CG2 1 
ATOM   7424 N N   . LEU B 1 458 ? 81.081  91.049  130.304 1.00 53.51  ? 458 LEU B N   1 
ATOM   7425 C CA  . LEU B 1 458 ? 81.235  90.685  128.898 1.00 53.51  ? 458 LEU B CA  1 
ATOM   7426 C C   . LEU B 1 458 ? 79.933  90.752  128.115 1.00 53.51  ? 458 LEU B C   1 
ATOM   7427 O O   . LEU B 1 458 ? 79.923  91.260  126.989 1.00 53.51  ? 458 LEU B O   1 
ATOM   7428 C CB  . LEU B 1 458 ? 81.826  89.277  128.758 1.00 53.51  ? 458 LEU B CB  1 
ATOM   7429 C CG  . LEU B 1 458 ? 82.802  88.725  129.793 1.00 53.51  ? 458 LEU B CG  1 
ATOM   7430 C CD1 . LEU B 1 458 ? 83.242  87.333  129.381 1.00 53.51  ? 458 LEU B CD1 1 
ATOM   7431 C CD2 . LEU B 1 458 ? 84.010  89.630  129.881 1.00 53.51  ? 458 LEU B CD2 1 
ATOM   7432 N N   . LEU B 1 459 ? 78.834  90.246  128.678 1.00 53.26  ? 459 LEU B N   1 
ATOM   7433 C CA  . LEU B 1 459 ? 77.555  90.299  127.978 1.00 53.26  ? 459 LEU B CA  1 
ATOM   7434 C C   . LEU B 1 459 ? 77.069  91.733  127.822 1.00 53.26  ? 459 LEU B C   1 
ATOM   7435 O O   . LEU B 1 459 ? 76.508  92.095  126.782 1.00 53.26  ? 459 LEU B O   1 
ATOM   7436 C CB  . LEU B 1 459 ? 76.515  89.451  128.711 1.00 53.26  ? 459 LEU B CB  1 
ATOM   7437 C CG  . LEU B 1 459 ? 76.692  87.932  128.644 1.00 53.26  ? 459 LEU B CG  1 
ATOM   7438 C CD1 . LEU B 1 459 ? 75.369  87.235  128.900 1.00 53.26  ? 459 LEU B CD1 1 
ATOM   7439 C CD2 . LEU B 1 459 ? 77.262  87.510  127.300 1.00 53.26  ? 459 LEU B CD2 1 
ATOM   7440 N N   . ILE B 1 460 ? 77.269  92.563  128.849 1.00 50.84  ? 460 ILE B N   1 
ATOM   7441 C CA  . ILE B 1 460 ? 76.894  93.971  128.757 1.00 50.84  ? 460 ILE B CA  1 
ATOM   7442 C C   . ILE B 1 460 ? 77.698  94.663  127.664 1.00 50.84  ? 460 ILE B C   1 
ATOM   7443 O O   . ILE B 1 460 ? 77.155  95.444  126.870 1.00 50.84  ? 460 ILE B O   1 
ATOM   7444 C CB  . ILE B 1 460 ? 77.079  94.660  130.122 1.00 50.84  ? 460 ILE B CB  1 
ATOM   7445 C CG1 . ILE B 1 460 ? 76.092  94.086  131.136 1.00 50.84  ? 460 ILE B CG1 1 
ATOM   7446 C CG2 . ILE B 1 460 ? 76.893  96.160  129.998 1.00 50.84  ? 460 ILE B CG2 1 
ATOM   7447 C CD1 . ILE B 1 460 ? 74.673  94.053  130.636 1.00 50.84  ? 460 ILE B CD1 1 
ATOM   7448 N N   . GLY B 1 461 ? 79.002  94.387  127.606 1.00 46.79  ? 461 GLY B N   1 
ATOM   7449 C CA  . GLY B 1 461 ? 79.824  94.950  126.549 1.00 46.79  ? 461 GLY B CA  1 
ATOM   7450 C C   . GLY B 1 461 ? 79.391  94.496  125.168 1.00 46.79  ? 461 GLY B C   1 
ATOM   7451 O O   . GLY B 1 461 ? 79.343  95.293  124.231 1.00 46.79  ? 461 GLY B O   1 
ATOM   7452 N N   . ALA B 1 462 ? 79.060  93.210  125.028 1.00 47.31  ? 462 ALA B N   1 
ATOM   7453 C CA  . ALA B 1 462 ? 78.601  92.699  123.741 1.00 47.31  ? 462 ALA B CA  1 
ATOM   7454 C C   . ALA B 1 462 ? 77.290  93.351  123.317 1.00 47.31  ? 462 ALA B C   1 
ATOM   7455 O O   . ALA B 1 462 ? 77.120  93.718  122.147 1.00 47.31  ? 462 ALA B O   1 
ATOM   7456 C CB  . ALA B 1 462 ? 78.448  91.180  123.805 1.00 47.31  ? 462 ALA B CB  1 
ATOM   7457 N N   . VAL B 1 463 ? 76.352  93.501  124.255 1.00 43.02  ? 463 VAL B N   1 
ATOM   7458 C CA  . VAL B 1 463 ? 75.070  94.127  123.940 1.00 43.02  ? 463 VAL B CA  1 
ATOM   7459 C C   . VAL B 1 463 ? 75.273  95.582  123.535 1.00 43.02  ? 463 VAL B C   1 
ATOM   7460 O O   . VAL B 1 463 ? 74.726  96.046  122.529 1.00 43.02  ? 463 VAL B O   1 
ATOM   7461 C CB  . VAL B 1 463 ? 74.101  93.999  125.129 1.00 43.02  ? 463 VAL B CB  1 
ATOM   7462 C CG1 . VAL B 1 463 ? 72.891  94.894  124.930 1.00 43.02  ? 463 VAL B CG1 1 
ATOM   7463 C CG2 . VAL B 1 463 ? 73.660  92.555  125.291 1.00 43.02  ? 463 VAL B CG2 1 
ATOM   7464 N N   . ILE B 1 464 ? 76.080  96.320  124.303 1.00 41.32  ? 464 ILE B N   1 
ATOM   7465 C CA  . ILE B 1 464 ? 76.319  97.721  123.983 1.00 41.32  ? 464 ILE B CA  1 
ATOM   7466 C C   . ILE B 1 464 ? 77.149  97.891  122.719 1.00 41.32  ? 464 ILE B C   1 
ATOM   7467 O O   . ILE B 1 464 ? 77.127  98.965  122.109 1.00 41.32  ? 464 ILE B O   1 
ATOM   7468 C CB  . ILE B 1 464 ? 76.972  98.441  125.179 1.00 41.32  ? 464 ILE B CB  1 
ATOM   7469 C CG1 . ILE B 1 464 ? 76.579  99.913  125.162 1.00 41.32  ? 464 ILE B CG1 1 
ATOM   7470 C CG2 . ILE B 1 464 ? 78.484  98.297  125.153 1.00 41.32  ? 464 ILE B CG2 1 
ATOM   7471 C CD1 . ILE B 1 464 ? 75.106  100.111 125.250 1.00 41.32  ? 464 ILE B CD1 1 
ATOM   7472 N N   . SER B 1 465 ? 77.880  96.861  122.302 1.00 42.94  ? 465 SER B N   1 
ATOM   7473 C CA  . SER B 1 465 ? 78.664  96.939  121.079 1.00 42.94  ? 465 SER B CA  1 
ATOM   7474 C C   . SER B 1 465 ? 77.874  96.538  119.843 1.00 42.94  ? 465 SER B C   1 
ATOM   7475 O O   . SER B 1 465 ? 78.176  97.018  118.745 1.00 42.94  ? 465 SER B O   1 
ATOM   7476 C CB  . SER B 1 465 ? 79.908  96.057  121.208 1.00 42.94  ? 465 SER B CB  1 
ATOM   7477 O OG  . SER B 1 465 ? 80.536  95.872  119.955 1.00 42.94  ? 465 SER B OG  1 
ATOM   7478 N N   . ILE B 1 466 ? 76.877  95.672  119.990 1.00 41.09  ? 466 ILE B N   1 
ATOM   7479 C CA  . ILE B 1 466 ? 76.129  95.141  118.852 1.00 41.09  ? 466 ILE B CA  1 
ATOM   7480 C C   . ILE B 1 466 ? 74.811  95.875  118.640 1.00 41.09  ? 466 ILE B C   1 
ATOM   7481 O O   . ILE B 1 466 ? 74.491  96.272  117.519 1.00 41.09  ? 466 ILE B O   1 
ATOM   7482 C CB  . ILE B 1 466 ? 75.904  93.622  119.032 1.00 41.09  ? 466 ILE B CB  1 
ATOM   7483 C CG1 . ILE B 1 466 ? 77.207  92.861  118.781 1.00 41.09  ? 466 ILE B CG1 1 
ATOM   7484 C CG2 . ILE B 1 466 ? 74.796  93.127  118.115 1.00 41.09  ? 466 ILE B CG2 1 
ATOM   7485 C CD1 . ILE B 1 466 ? 77.584  92.761  117.320 1.00 41.09  ? 466 ILE B CD1 1 
ATOM   7486 N N   . LEU B 1 467 ? 74.032  96.067  119.708 1.00 40.43  ? 467 LEU B N   1 
ATOM   7487 C CA  . LEU B 1 467 ? 72.644  96.509  119.564 1.00 40.43  ? 467 LEU B CA  1 
ATOM   7488 C C   . LEU B 1 467 ? 72.472  97.865  118.879 1.00 40.43  ? 467 LEU B C   1 
ATOM   7489 O O   . LEU B 1 467 ? 71.590  97.970  118.009 1.00 40.43  ? 467 LEU B O   1 
ATOM   7490 C CB  . LEU B 1 467 ? 71.956  96.492  120.934 1.00 40.43  ? 467 LEU B CB  1 
ATOM   7491 C CG  . LEU B 1 467 ? 70.506  96.978  120.951 1.00 40.43  ? 467 LEU B CG  1 
ATOM   7492 C CD1 . LEU B 1 467 ? 69.638  96.101  120.067 1.00 40.43  ? 467 LEU B CD1 1 
ATOM   7493 C CD2 . LEU B 1 467 ? 69.960  97.005  122.367 1.00 40.43  ? 467 LEU B CD2 1 
ATOM   7494 N N   . PRO B 1 468 ? 73.222  98.930  119.216 1.00 38.06  ? 468 PRO B N   1 
ATOM   7495 C CA  . PRO B 1 468 ? 72.999  100.207 118.506 1.00 38.06  ? 468 PRO B CA  1 
ATOM   7496 C C   . PRO B 1 468 ? 73.220  100.124 117.005 1.00 38.06  ? 468 PRO B C   1 
ATOM   7497 O O   . PRO B 1 468 ? 72.504  100.786 116.239 1.00 38.06  ? 468 PRO B O   1 
ATOM   7498 C CB  . PRO B 1 468 ? 74.003  101.153 119.176 1.00 38.06  ? 468 PRO B CB  1 
ATOM   7499 C CG  . PRO B 1 468 ? 74.202  100.584 120.521 1.00 38.06  ? 468 PRO B CG  1 
ATOM   7500 C CD  . PRO B 1 468 ? 74.188  99.104  120.317 1.00 38.06  ? 468 PRO B CD  1 
ATOM   7501 N N   . HIS B 1 469 ? 74.191  99.320  116.565 1.00 39.05  ? 469 HIS B N   1 
ATOM   7502 C CA  . HIS B 1 469 ? 74.419  99.146  115.135 1.00 39.05  ? 469 HIS B CA  1 
ATOM   7503 C C   . HIS B 1 469 ? 73.202  98.532  114.454 1.00 39.05  ? 469 HIS B C   1 
ATOM   7504 O O   . HIS B 1 469 ? 72.794  98.984  113.379 1.00 39.05  ? 469 HIS B O   1 
ATOM   7505 C CB  . HIS B 1 469 ? 75.656  98.282  114.900 1.00 39.05  ? 469 HIS B CB  1 
ATOM   7506 C CG  . HIS B 1 469 ? 76.944  98.967  115.235 1.00 39.05  ? 469 HIS B CG  1 
ATOM   7507 N ND1 . HIS B 1 469 ? 77.426  100.039 114.514 1.00 39.05  ? 469 HIS B ND1 1 
ATOM   7508 C CD2 . HIS B 1 469 ? 77.850  98.735  116.214 1.00 39.05  ? 469 HIS B CD2 1 
ATOM   7509 C CE1 . HIS B 1 469 ? 78.574  100.435 115.034 1.00 39.05  ? 469 HIS B CE1 1 
ATOM   7510 N NE2 . HIS B 1 469 ? 78.853  99.661  116.067 1.00 39.05  ? 469 HIS B NE2 1 
ATOM   7511 N N   . ILE B 1 470 ? 72.601  97.513  115.075 1.00 39.85  ? 470 ILE B N   1 
ATOM   7512 C CA  . ILE B 1 470 ? 71.423  96.868  114.497 1.00 39.85  ? 470 ILE B CA  1 
ATOM   7513 C C   . ILE B 1 470 ? 70.262  97.851  114.409 1.00 39.85  ? 470 ILE B C   1 
ATOM   7514 O O   . ILE B 1 470 ? 69.568  97.926  113.387 1.00 39.85  ? 470 ILE B O   1 
ATOM   7515 C CB  . ILE B 1 470 ? 71.043  95.620  115.315 1.00 39.85  ? 470 ILE B CB  1 
ATOM   7516 C CG1 . ILE B 1 470 ? 72.116  94.539  115.175 1.00 39.85  ? 470 ILE B CG1 1 
ATOM   7517 C CG2 . ILE B 1 470 ? 69.691  95.082  114.877 1.00 39.85  ? 470 ILE B CG2 1 
ATOM   7518 C CD1 . ILE B 1 470 ? 71.741  93.216  115.806 1.00 39.85  ? 470 ILE B CD1 1 
ATOM   7519 N N   . ILE B 1 471 ? 70.038  98.620  115.478 1.00 41.37  ? 471 ILE B N   1 
ATOM   7520 C CA  . ILE B 1 471 ? 68.929  99.571  115.505 1.00 41.37  ? 471 ILE B CA  1 
ATOM   7521 C C   . ILE B 1 471 ? 69.100  100.623 114.417 1.00 41.37  ? 471 ILE B C   1 
ATOM   7522 O O   . ILE B 1 471 ? 68.170  100.910 113.651 1.00 41.37  ? 471 ILE B O   1 
ATOM   7523 C CB  . ILE B 1 471 ? 68.814  100.218 116.897 1.00 41.37  ? 471 ILE B CB  1 
ATOM   7524 C CG1 . ILE B 1 471 ? 68.484  99.163  117.952 1.00 41.37  ? 471 ILE B CG1 1 
ATOM   7525 C CG2 . ILE B 1 471 ? 67.767  101.322 116.890 1.00 41.37  ? 471 ILE B CG2 1 
ATOM   7526 C CD1 . ILE B 1 471 ? 68.268  99.732  119.336 1.00 41.37  ? 471 ILE B CD1 1 
ATOM   7527 N N   . THR B 1 472 ? 70.299  101.205 114.322 1.00 45.60  ? 472 THR B N   1 
ATOM   7528 C CA  . THR B 1 472 ? 70.507  102.253 113.330 1.00 45.60  ? 472 THR B CA  1 
ATOM   7529 C C   . THR B 1 472 ? 70.501  101.699 111.908 1.00 45.60  ? 472 THR B C   1 
ATOM   7530 O O   . THR B 1 472 ? 70.034  102.380 110.990 1.00 45.60  ? 472 THR B O   1 
ATOM   7531 C CB  . THR B 1 472 ? 71.791  103.033 113.645 1.00 45.60  ? 472 THR B CB  1 
ATOM   7532 O OG1 . THR B 1 472 ? 71.689  104.362 113.119 1.00 45.60  ? 472 THR B OG1 1 
ATOM   7533 C CG2 . THR B 1 472 ? 73.033  102.356 113.095 1.00 45.60  ? 472 THR B CG2 1 
ATOM   7534 N N   . PHE B 1 473 ? 70.952  100.455 111.709 1.00 47.36  ? 473 PHE B N   1 
ATOM   7535 C CA  . PHE B 1 473 ? 70.897  99.846  110.385 1.00 47.36  ? 473 PHE B CA  1 
ATOM   7536 C C   . PHE B 1 473 ? 69.448  99.628  109.969 1.00 47.36  ? 473 PHE B C   1 
ATOM   7537 O O   . PHE B 1 473 ? 69.065  99.936  108.835 1.00 47.36  ? 473 PHE B O   1 
ATOM   7538 C CB  . PHE B 1 473 ? 71.693  98.532  110.400 1.00 47.36  ? 473 PHE B CB  1 
ATOM   7539 C CG  . PHE B 1 473 ? 71.175  97.453  109.471 1.00 47.36  ? 473 PHE B CG  1 
ATOM   7540 C CD1 . PHE B 1 473 ? 70.996  97.684  108.111 1.00 47.36  ? 473 PHE B CD1 1 
ATOM   7541 C CD2 . PHE B 1 473 ? 70.853  96.204  109.973 1.00 47.36  ? 473 PHE B CD2 1 
ATOM   7542 C CE1 . PHE B 1 473 ? 70.519  96.688  107.280 1.00 47.36  ? 473 PHE B CE1 1 
ATOM   7543 C CE2 . PHE B 1 473 ? 70.375  95.208  109.147 1.00 47.36  ? 473 PHE B CE2 1 
ATOM   7544 C CZ  . PHE B 1 473 ? 70.208  95.449  107.799 1.00 47.36  ? 473 PHE B CZ  1 
ATOM   7545 N N   . VAL B 1 474 ? 68.625  99.109  110.884 1.00 48.56  ? 474 VAL B N   1 
ATOM   7546 C CA  . VAL B 1 474 ? 67.216  98.875  110.578 1.00 48.56  ? 474 VAL B CA  1 
ATOM   7547 C C   . VAL B 1 474 ? 66.521  100.192 110.253 1.00 48.56  ? 474 VAL B C   1 
ATOM   7548 O O   . VAL B 1 474 ? 65.808  100.306 109.247 1.00 48.56  ? 474 VAL B O   1 
ATOM   7549 C CB  . VAL B 1 474 ? 66.532  98.141  111.746 1.00 48.56  ? 474 VAL B CB  1 
ATOM   7550 C CG1 . VAL B 1 474 ? 65.031  98.386  111.736 1.00 48.56  ? 474 VAL B CG1 1 
ATOM   7551 C CG2 . VAL B 1 474 ? 66.829  96.652  111.679 1.00 48.56  ? 474 VAL B CG2 1 
ATOM   7552 N N   . ILE B 1 475 ? 66.753  101.217 111.080 1.00 50.10  ? 475 ILE B N   1 
ATOM   7553 C CA  . ILE B 1 475 ? 66.096  102.505 110.875 1.00 50.10  ? 475 ILE B CA  1 
ATOM   7554 C C   . ILE B 1 475 ? 66.526  103.130 109.553 1.00 50.10  ? 475 ILE B C   1 
ATOM   7555 O O   . ILE B 1 475 ? 65.697  103.658 108.802 1.00 50.10  ? 475 ILE B O   1 
ATOM   7556 C CB  . ILE B 1 475 ? 66.376  103.441 112.066 1.00 50.10  ? 475 ILE B CB  1 
ATOM   7557 C CG1 . ILE B 1 475 ? 65.613  102.968 113.303 1.00 50.10  ? 475 ILE B CG1 1 
ATOM   7558 C CG2 . ILE B 1 475 ? 65.991  104.873 111.732 1.00 50.10  ? 475 ILE B CG2 1 
ATOM   7559 C CD1 . ILE B 1 475 ? 65.770  103.880 114.502 1.00 50.10  ? 475 ILE B CD1 1 
ATOM   7560 N N   . CYS B 1 476 ? 67.821  103.068 109.236 1.00 55.99  ? 476 CYS B N   1 
ATOM   7561 C CA  . CYS B 1 476 ? 68.311  103.704 108.018 1.00 55.99  ? 476 CYS B CA  1 
ATOM   7562 C C   . CYS B 1 476 ? 67.857  102.961 106.766 1.00 55.99  ? 476 CYS B C   1 
ATOM   7563 O O   . CYS B 1 476 ? 67.447  103.590 105.783 1.00 55.99  ? 476 CYS B O   1 
ATOM   7564 C CB  . CYS B 1 476 ? 69.836  103.804 108.059 1.00 55.99  ? 476 CYS B CB  1 
ATOM   7565 N N   . TYR B 1 477 ? 67.921  101.627 106.774 1.00 60.14  ? 477 TYR B N   1 
ATOM   7566 C CA  . TYR B 1 477 ? 67.692  100.878 105.545 1.00 60.14  ? 477 TYR B CA  1 
ATOM   7567 C C   . TYR B 1 477 ? 66.211  100.605 105.300 1.00 60.14  ? 477 TYR B C   1 
ATOM   7568 O O   . TYR B 1 477 ? 65.735  100.752 104.170 1.00 60.14  ? 477 TYR B O   1 
ATOM   7569 C CB  . TYR B 1 477 ? 68.475  99.565  105.581 1.00 60.14  ? 477 TYR B CB  1 
ATOM   7570 C CG  . TYR B 1 477 ? 68.263  98.683  104.372 1.00 60.14  ? 477 TYR B CG  1 
ATOM   7571 C CD1 . TYR B 1 477 ? 68.480  99.167  103.089 1.00 60.14  ? 477 TYR B CD1 1 
ATOM   7572 C CD2 . TYR B 1 477 ? 67.852  97.365  104.515 1.00 60.14  ? 477 TYR B CD2 1 
ATOM   7573 C CE1 . TYR B 1 477 ? 68.290  98.362  101.982 1.00 60.14  ? 477 TYR B CE1 1 
ATOM   7574 C CE2 . TYR B 1 477 ? 67.659  96.554  103.413 1.00 60.14  ? 477 TYR B CE2 1 
ATOM   7575 C CZ  . TYR B 1 477 ? 67.879  97.058  102.149 1.00 60.14  ? 477 TYR B CZ  1 
ATOM   7576 O OH  . TYR B 1 477 ? 67.687  96.253  101.050 1.00 60.14  ? 477 TYR B OH  1 
ATOM   7577 N N   . TYR B 1 478 ? 65.465  100.208 106.332 1.00 59.83  ? 478 TYR B N   1 
ATOM   7578 C CA  . TYR B 1 478 ? 64.085  99.788  106.116 1.00 59.83  ? 478 TYR B CA  1 
ATOM   7579 C C   . TYR B 1 478 ? 63.097  100.947 106.179 1.00 59.83  ? 478 TYR B C   1 
ATOM   7580 O O   . TYR B 1 478 ? 62.209  101.053 105.330 1.00 59.83  ? 478 TYR B O   1 
ATOM   7581 C CB  . TYR B 1 478 ? 63.696  98.712  107.133 1.00 59.83  ? 478 TYR B CB  1 
ATOM   7582 C CG  . TYR B 1 478 ? 64.399  97.396  106.915 1.00 59.83  ? 478 TYR B CG  1 
ATOM   7583 C CD1 . TYR B 1 478 ? 64.234  96.689  105.734 1.00 59.83  ? 478 TYR B CD1 1 
ATOM   7584 C CD2 . TYR B 1 478 ? 65.225  96.857  107.892 1.00 59.83  ? 478 TYR B CD2 1 
ATOM   7585 C CE1 . TYR B 1 478 ? 64.873  95.484  105.527 1.00 59.83  ? 478 TYR B CE1 1 
ATOM   7586 C CE2 . TYR B 1 478 ? 65.869  95.652  107.695 1.00 59.83  ? 478 TYR B CE2 1 
ATOM   7587 C CZ  . TYR B 1 478 ? 65.690  94.970  106.511 1.00 59.83  ? 478 TYR B CZ  1 
ATOM   7588 O OH  . TYR B 1 478 ? 66.327  93.769  106.309 1.00 59.83  ? 478 TYR B OH  1 
ATOM   7589 N N   . LEU B 1 479 ? 63.230  101.819 107.176 1.00 61.35  ? 479 LEU B N   1 
ATOM   7590 C CA  . LEU B 1 479 ? 62.261  102.893 107.360 1.00 61.35  ? 479 LEU B CA  1 
ATOM   7591 C C   . LEU B 1 479 ? 62.600  104.127 106.531 1.00 61.35  ? 479 LEU B C   1 
ATOM   7592 O O   . LEU B 1 479 ? 61.756  104.620 105.777 1.00 61.35  ? 479 LEU B O   1 
ATOM   7593 C CB  . LEU B 1 479 ? 62.155  103.269 108.843 1.00 61.35  ? 479 LEU B CB  1 
ATOM   7594 C CG  . LEU B 1 479 ? 61.309  102.395 109.779 1.00 61.35  ? 479 LEU B CG  1 
ATOM   7595 C CD1 . LEU B 1 479 ? 61.902  101.005 109.991 1.00 61.35  ? 479 LEU B CD1 1 
ATOM   7596 C CD2 . LEU B 1 479 ? 61.099  103.099 111.113 1.00 61.35  ? 479 LEU B CD2 1 
ATOM   7597 N N   . MET B 1 480 ? 63.824  104.644 106.663 1.00 65.17  ? 480 MET B N   1 
ATOM   7598 C CA  . MET B 1 480 ? 64.186  105.868 105.961 1.00 65.17  ? 480 MET B CA  1 
ATOM   7599 C C   . MET B 1 480 ? 64.617  105.618 104.522 1.00 65.17  ? 480 MET B C   1 
ATOM   7600 O O   . MET B 1 480 ? 64.550  106.545 103.707 1.00 65.17  ? 480 MET B O   1 
ATOM   7601 C CB  . MET B 1 480 ? 65.296  106.605 106.717 1.00 65.17  ? 480 MET B CB  1 
ATOM   7602 C CG  . MET B 1 480 ? 65.094  108.116 106.770 1.00 65.17  ? 480 MET B CG  1 
ATOM   7603 S SD  . MET B 1 480 ? 66.411  108.997 107.627 1.00 65.17  ? 480 MET B SD  1 
ATOM   7604 C CE  . MET B 1 480 ? 67.206  109.842 106.259 1.00 65.17  ? 480 MET B CE  1 
ATOM   7605 N N   . LYS B 1 481 ? 65.049  104.396 104.198 1.00 68.43  ? 481 LYS B N   1 
ATOM   7606 C CA  . LYS B 1 481 ? 65.416  103.994 102.838 1.00 68.43  ? 481 LYS B CA  1 
ATOM   7607 C C   . LYS B 1 481 ? 66.536  104.873 102.277 1.00 68.43  ? 481 LYS B C   1 
ATOM   7608 O O   . LYS B 1 481 ? 66.353  105.634 101.322 1.00 68.43  ? 481 LYS B O   1 
ATOM   7609 C CB  . LYS B 1 481 ? 64.193  104.004 101.913 1.00 68.43  ? 481 LYS B CB  1 
ATOM   7610 C CG  . LYS B 1 481 ? 62.961  103.345 102.504 1.00 68.43  ? 481 LYS B CG  1 
ATOM   7611 C CD  . LYS B 1 481 ? 61.706  103.806 101.784 1.00 68.43  ? 481 LYS B CD  1 
ATOM   7612 C CE  . LYS B 1 481 ? 60.449  103.357 102.509 1.00 68.43  ? 481 LYS B CE  1 
ATOM   7613 N NZ  . LYS B 1 481 ? 59.227  103.959 101.903 1.00 68.43  ? 481 LYS B NZ  1 
ATOM   7614 N N   . MET B 1 482 ? 67.707  104.764 102.901 1.00 70.81  ? 482 MET B N   1 
ATOM   7615 C CA  . MET B 1 482 ? 68.890  105.475 102.450 1.00 70.81  ? 482 MET B CA  1 
ATOM   7616 C C   . MET B 1 482 ? 69.609  104.669 101.371 1.00 70.81  ? 482 MET B C   1 
ATOM   7617 O O   . MET B 1 482 ? 69.167  103.595 100.956 1.00 70.81  ? 482 MET B O   1 
ATOM   7618 C CB  . MET B 1 482 ? 69.830  105.747 103.621 1.00 70.81  ? 482 MET B CB  1 
ATOM   7619 C CG  . MET B 1 482 ? 69.429  106.911 104.500 1.00 70.81  ? 482 MET B CG  1 
ATOM   7620 S SD  . MET B 1 482 ? 70.681  107.243 105.754 1.00 70.81  ? 482 MET B SD  1 
ATOM   7621 C CE  . MET B 1 482 ? 69.678  107.386 107.231 1.00 70.81  ? 482 MET B CE  1 
ATOM   7622 N N   . GLU B 1 483 ? 70.739  105.199 100.909 1.00 70.43  ? 483 GLU B N   1 
ATOM   7623 C CA  . GLU B 1 483 ? 71.605  104.480 99.991  1.00 70.43  ? 483 GLU B CA  1 
ATOM   7624 C C   . GLU B 1 483 ? 72.382  103.399 100.743 1.00 70.43  ? 483 GLU B C   1 
ATOM   7625 O O   . GLU B 1 483 ? 72.622  103.522 101.947 1.00 70.43  ? 483 GLU B O   1 
ATOM   7626 C CB  . GLU B 1 483 ? 72.566  105.448 99.305  1.00 70.43  ? 483 GLU B CB  1 
ATOM   7627 C CG  . GLU B 1 483 ? 73.137  106.505 100.223 1.00 70.43  ? 483 GLU B CG  1 
ATOM   7628 C CD  . GLU B 1 483 ? 73.772  107.656 99.467  1.00 70.43  ? 483 GLU B CD  1 
ATOM   7629 O OE1 . GLU B 1 483 ? 73.943  107.540 98.235  1.00 70.43  ? 483 GLU B OE1 1 
ATOM   7630 O OE2 . GLU B 1 483 ? 74.107  108.673 100.110 1.00 70.43  ? 483 GLU B OE2 1 
ATOM   7631 N N   . PRO B 1 484 ? 72.778  102.319 100.058 1.00 67.64  ? 484 PRO B N   1 
ATOM   7632 C CA  . PRO B 1 484 ? 73.364  101.170 100.765 1.00 67.64  ? 484 PRO B CA  1 
ATOM   7633 C C   . PRO B 1 484 ? 74.715  101.431 101.417 1.00 67.64  ? 484 PRO B C   1 
ATOM   7634 O O   . PRO B 1 484 ? 74.900  101.129 102.599 1.00 67.64  ? 484 PRO B O   1 
ATOM   7635 C CB  . PRO B 1 484 ? 73.489  100.114 99.658  1.00 67.64  ? 484 PRO B CB  1 
ATOM   7636 C CG  . PRO B 1 484 ? 72.499  100.529 98.622  1.00 67.64  ? 484 PRO B CG  1 
ATOM   7637 C CD  . PRO B 1 484 ? 72.542  102.019 98.635  1.00 67.64  ? 484 PRO B CD  1 
ATOM   7638 N N   . ILE B 1 485 ? 75.666  101.987 100.665 1.00 61.58  ? 485 ILE B N   1 
ATOM   7639 C CA  . ILE B 1 485 ? 77.044  102.038 101.144 1.00 61.58  ? 485 ILE B CA  1 
ATOM   7640 C C   . ILE B 1 485 ? 77.243  103.156 102.169 1.00 61.58  ? 485 ILE B C   1 
ATOM   7641 O O   . ILE B 1 485 ? 78.047  103.013 103.105 1.00 61.58  ? 485 ILE B O   1 
ATOM   7642 C CB  . ILE B 1 485 ? 77.995  102.170 99.941  1.00 61.58  ? 485 ILE B CB  1 
ATOM   7643 C CG1 . ILE B 1 485 ? 78.141  100.818 99.245  1.00 61.58  ? 485 ILE B CG1 1 
ATOM   7644 C CG2 . ILE B 1 485 ? 79.370  102.669 100.359 1.00 61.58  ? 485 ILE B CG2 1 
ATOM   7645 C CD1 . ILE B 1 485 ? 78.761  99.751  100.117 1.00 61.58  ? 485 ILE B CD1 1 
ATOM   7646 N N   . SER B 1 486 ? 76.512  104.266 102.031 1.00 54.97  ? 486 SER B N   1 
ATOM   7647 C CA  . SER B 1 486 ? 76.656  105.358 102.987 1.00 54.97  ? 486 SER B CA  1 
ATOM   7648 C C   . SER B 1 486 ? 76.218  104.946 104.383 1.00 54.97  ? 486 SER B C   1 
ATOM   7649 O O   . SER B 1 486 ? 76.695  105.511 105.369 1.00 54.97  ? 486 SER B O   1 
ATOM   7650 C CB  . SER B 1 486 ? 75.864  106.581 102.529 1.00 54.97  ? 486 SER B CB  1 
ATOM   7651 O OG  . SER B 1 486 ? 74.564  106.580 103.092 1.00 54.97  ? 486 SER B OG  1 
ATOM   7652 N N   . ILE B 1 487 ? 75.321  103.962 104.492 1.00 50.53  ? 487 ILE B N   1 
ATOM   7653 C CA  . ILE B 1 487 ? 74.947  103.438 105.804 1.00 50.53  ? 487 ILE B CA  1 
ATOM   7654 C C   . ILE B 1 487 ? 76.154  102.803 106.483 1.00 50.53  ? 487 ILE B C   1 
ATOM   7655 O O   . ILE B 1 487 ? 76.456  103.087 107.651 1.00 50.53  ? 487 ILE B O   1 
ATOM   7656 C CB  . ILE B 1 487 ? 73.785  102.436 105.669 1.00 50.53  ? 487 ILE B CB  1 
ATOM   7657 C CG1 . ILE B 1 487 ? 72.505  103.156 105.244 1.00 50.53  ? 487 ILE B CG1 1 
ATOM   7658 C CG2 . ILE B 1 487 ? 73.572  101.684 106.971 1.00 50.53  ? 487 ILE B CG2 1 
ATOM   7659 C CD1 . ILE B 1 487 ? 71.330  102.229 105.032 1.00 50.53  ? 487 ILE B CD1 1 
ATOM   7660 N N   . ILE B 1 488 ? 76.871  101.947 105.749 1.00 44.25  ? 488 ILE B N   1 
ATOM   7661 C CA  . ILE B 1 488 ? 78.088  101.329 106.271 1.00 44.25  ? 488 ILE B CA  1 
ATOM   7662 C C   . ILE B 1 488 ? 79.105  102.397 106.644 1.00 44.25  ? 488 ILE B C   1 
ATOM   7663 O O   . ILE B 1 488 ? 79.722  102.347 107.717 1.00 44.25  ? 488 ILE B O   1 
ATOM   7664 C CB  . ILE B 1 488 ? 78.664  100.341 105.238 1.00 44.25  ? 488 ILE B CB  1 
ATOM   7665 C CG1 . ILE B 1 488 ? 77.833  99.062  105.188 1.00 44.25  ? 488 ILE B CG1 1 
ATOM   7666 C CG2 . ILE B 1 488 ? 80.115  100.016 105.551 1.00 44.25  ? 488 ILE B CG2 1 
ATOM   7667 C CD1 . ILE B 1 488 ? 77.826  98.302  106.485 1.00 44.25  ? 488 ILE B CD1 1 
ATOM   7668 N N   . GLY B 1 489 ? 79.288  103.383 105.765 1.00 48.27  ? 489 GLY B N   1 
ATOM   7669 C CA  . GLY B 1 489 ? 80.262  104.430 106.033 1.00 48.27  ? 489 GLY B CA  1 
ATOM   7670 C C   . GLY B 1 489 ? 79.936  105.227 107.282 1.00 48.27  ? 489 GLY B C   1 
ATOM   7671 O O   . GLY B 1 489 ? 80.798  105.456 108.133 1.00 48.27  ? 489 GLY B O   1 
ATOM   7672 N N   . ALA B 1 490 ? 78.674  105.641 107.417 1.00 42.63  ? 490 ALA B N   1 
ATOM   7673 C CA  . ALA B 1 490 ? 78.268  106.437 108.569 1.00 42.63  ? 490 ALA B CA  1 
ATOM   7674 C C   . ALA B 1 490 ? 78.371  105.640 109.860 1.00 42.63  ? 490 ALA B C   1 
ATOM   7675 O O   . ALA B 1 490 ? 78.808  106.172 110.884 1.00 42.63  ? 490 ALA B O   1 
ATOM   7676 C CB  . ALA B 1 490 ? 76.847  106.958 108.370 1.00 42.63  ? 490 ALA B CB  1 
ATOM   7677 N N   . GLN B 1 491 ? 77.983  104.362 109.836 1.00 44.08  ? 491 GLN B N   1 
ATOM   7678 C CA  . GLN B 1 491 ? 78.075  103.563 111.053 1.00 44.08  ? 491 GLN B CA  1 
ATOM   7679 C C   . GLN B 1 491 ? 79.526  103.327 111.455 1.00 44.08  ? 491 GLN B C   1 
ATOM   7680 O O   . GLN B 1 491 ? 79.876  103.450 112.637 1.00 44.08  ? 491 GLN B O   1 
ATOM   7681 C CB  . GLN B 1 491 ? 77.340  102.238 110.865 1.00 44.08  ? 491 GLN B CB  1 
ATOM   7682 C CG  . GLN B 1 491 ? 75.843  102.406 110.697 1.00 44.08  ? 491 GLN B CG  1 
ATOM   7683 C CD  . GLN B 1 491 ? 75.125  101.094 110.475 1.00 44.08  ? 491 GLN B CD  1 
ATOM   7684 O OE1 . GLN B 1 491 ? 73.911  101.064 110.294 1.00 44.08  ? 491 GLN B OE1 1 
ATOM   7685 N NE2 . GLN B 1 491 ? 75.872  99.998  110.495 1.00 44.08  ? 491 GLN B NE2 1 
ATOM   7686 N N   . THR B 1 492 ? 80.395  103.022 110.487 1.00 42.09  ? 492 THR B N   1 
ATOM   7687 C CA  . THR B 1 492 ? 81.796  102.787 110.807 1.00 42.09  ? 492 THR B CA  1 
ATOM   7688 C C   . THR B 1 492 ? 82.538  104.068 111.158 1.00 42.09  ? 492 THR B C   1 
ATOM   7689 O O   . THR B 1 492 ? 83.608  103.998 111.772 1.00 42.09  ? 492 THR B O   1 
ATOM   7690 C CB  . THR B 1 492 ? 82.494  102.067 109.646 1.00 42.09  ? 492 THR B CB  1 
ATOM   7691 O OG1 . THR B 1 492 ? 83.604  101.311 110.145 1.00 42.09  ? 492 THR B OG1 1 
ATOM   7692 C CG2 . THR B 1 492 ? 82.985  103.052 108.600 1.00 42.09  ? 492 THR B CG2 1 
ATOM   7693 N N   . GLY B 1 493 ? 82.006  105.228 110.781 1.00 40.32  ? 493 GLY B N   1 
ATOM   7694 C CA  . GLY B 1 493 ? 82.581  106.479 111.228 1.00 40.32  ? 493 GLY B CA  1 
ATOM   7695 C C   . GLY B 1 493 ? 82.110  106.867 112.614 1.00 40.32  ? 493 GLY B C   1 
ATOM   7696 O O   . GLY B 1 493 ? 82.888  107.387 113.420 1.00 40.32  ? 493 GLY B O   1 
ATOM   7697 N N   . ALA B 1 494 ? 80.826  106.630 112.896 1.00 37.63  ? 494 ALA B N   1 
ATOM   7698 C CA  . ALA B 1 494 ? 80.282  106.928 114.216 1.00 37.63  ? 494 ALA B CA  1 
ATOM   7699 C C   . ALA B 1 494 ? 80.898  106.036 115.285 1.00 37.63  ? 494 ALA B C   1 
ATOM   7700 O O   . ALA B 1 494 ? 81.184  106.497 116.395 1.00 37.63  ? 494 ALA B O   1 
ATOM   7701 C CB  . ALA B 1 494 ? 78.762  106.776 114.203 1.00 37.63  ? 494 ALA B CB  1 
ATOM   7702 N N   . ASP B 1 495 ? 81.107  104.755 114.974 1.00 37.66  ? 495 ASP B N   1 
ATOM   7703 C CA  . ASP B 1 495 ? 81.733  103.870 115.948 1.00 37.66  ? 495 ASP B CA  1 
ATOM   7704 C C   . ASP B 1 495 ? 83.237  104.092 116.056 1.00 37.66  ? 495 ASP B C   1 
ATOM   7705 O O   . ASP B 1 495 ? 83.866  103.509 116.946 1.00 37.66  ? 495 ASP B O   1 
ATOM   7706 C CB  . ASP B 1 495 ? 81.446  102.410 115.604 1.00 37.66  ? 495 ASP B CB  1 
ATOM   7707 C CG  . ASP B 1 495 ? 81.440  101.522 116.829 1.00 37.66  ? 495 ASP B CG  1 
ATOM   7708 O OD1 . ASP B 1 495 ? 81.583  102.061 117.946 1.00 37.66  ? 495 ASP B OD1 1 
ATOM   7709 O OD2 . ASP B 1 495 ? 81.295  100.292 116.677 1.00 37.66  ? 495 ASP B OD2 1 
ATOM   7710 N N   . THR B 1 496 ? 83.816  104.914 115.173 1.00 37.33  ? 496 THR B N   1 
ATOM   7711 C CA  . THR B 1 496 ? 85.234  105.289 115.199 1.00 37.33  ? 496 THR B CA  1 
ATOM   7712 C C   . THR B 1 496 ? 86.147  104.064 115.140 1.00 37.33  ? 496 THR B C   1 
ATOM   7713 O O   . THR B 1 496 ? 87.013  103.865 115.991 1.00 37.33  ? 496 THR B O   1 
ATOM   7714 C CB  . THR B 1 496 ? 85.571  106.153 116.421 1.00 37.33  ? 496 THR B CB  1 
ATOM   7715 O OG1 . THR B 1 496 ? 85.313  105.425 117.626 1.00 37.33  ? 496 THR B OG1 1 
ATOM   7716 C CG2 . THR B 1 496 ? 84.735  107.417 116.419 1.00 37.33  ? 496 THR B CG2 1 
ATOM   7717 N N   . LEU B 1 497 ? 85.938  103.228 114.125 1.00 41.48  ? 497 LEU B N   1 
ATOM   7718 C CA  . LEU B 1 497 ? 86.731  102.017 113.940 1.00 41.48  ? 497 LEU B CA  1 
ATOM   7719 C C   . LEU B 1 497 ? 87.688  102.196 112.766 1.00 41.48  ? 497 LEU B C   1 
ATOM   7720 O O   . LEU B 1 497 ? 87.295  102.047 111.603 1.00 41.48  ? 497 LEU B O   1 
ATOM   7721 C CB  . LEU B 1 497 ? 85.822  100.813 113.728 1.00 41.48  ? 497 LEU B CB  1 
ATOM   7722 C CG  . LEU B 1 497 ? 85.232  100.293 115.029 1.00 41.48  ? 497 LEU B CG  1 
ATOM   7723 C CD1 . LEU B 1 497 ? 83.926  99.617  114.741 1.00 41.48  ? 497 LEU B CD1 1 
ATOM   7724 C CD2 . LEU B 1 497 ? 86.200  99.338  115.704 1.00 41.48  ? 497 LEU B CD2 1 
ATOM   7725 N N   . SER B 1 498 ? 88.955  102.469 113.079 1.00 48.48  ? 498 SER B N   1 
ATOM   7726 C CA  . SER B 1 498 ? 89.967  102.637 112.043 1.00 48.48  ? 498 SER B CA  1 
ATOM   7727 C C   . SER B 1 498 ? 90.298  101.314 111.366 1.00 48.48  ? 498 SER B C   1 
ATOM   7728 O O   . SER B 1 498 ? 90.575  101.285 110.161 1.00 48.48  ? 498 SER B O   1 
ATOM   7729 C CB  . SER B 1 498 ? 91.227  103.259 112.644 1.00 48.48  ? 498 SER B CB  1 
ATOM   7730 O OG  . SER B 1 498 ? 90.908  104.405 113.413 1.00 48.48  ? 498 SER B OG  1 
ATOM   7731 N N   . ALA B 1 499 ? 90.278  100.213 112.122 1.00 50.74  ? 499 ALA B N   1 
ATOM   7732 C CA  . ALA B 1 499 ? 90.504  98.903  111.519 1.00 50.74  ? 499 ALA B CA  1 
ATOM   7733 C C   . ALA B 1 499 ? 89.409  98.563  110.517 1.00 50.74  ? 499 ALA B C   1 
ATOM   7734 O O   . ALA B 1 499 ? 89.696  98.072  109.418 1.00 50.74  ? 499 ALA B O   1 
ATOM   7735 C CB  . ALA B 1 499 ? 90.590  97.832  112.606 1.00 50.74  ? 499 ALA B CB  1 
ATOM   7736 N N   . ALA B 1 500 ? 88.150  98.824  110.877 1.00 53.15  ? 500 ALA B N   1 
ATOM   7737 C CA  . ALA B 1 500 ? 87.052  98.599  109.943 1.00 53.15  ? 500 ALA B CA  1 
ATOM   7738 C C   . ALA B 1 500 ? 87.155  99.525  108.739 1.00 53.15  ? 500 ALA B C   1 
ATOM   7739 O O   . ALA B 1 500 ? 86.889  99.109  107.604 1.00 53.15  ? 500 ALA B O   1 
ATOM   7740 C CB  . ALA B 1 500 ? 85.711  98.786  110.650 1.00 53.15  ? 500 ALA B CB  1 
ATOM   7741 N N   . LEU B 1 501 ? 87.540  100.784 108.972 1.00 52.92  ? 501 LEU B N   1 
ATOM   7742 C CA  . LEU B 1 501 ? 87.761  101.722 107.873 1.00 52.92  ? 501 LEU B CA  1 
ATOM   7743 C C   . LEU B 1 501 ? 88.775  101.168 106.882 1.00 52.92  ? 501 LEU B C   1 
ATOM   7744 O O   . LEU B 1 501 ? 88.513  101.105 105.676 1.00 52.92  ? 501 LEU B O   1 
ATOM   7745 C CB  . LEU B 1 501 ? 88.233  103.067 108.433 1.00 52.92  ? 501 LEU B CB  1 
ATOM   7746 C CG  . LEU B 1 501 ? 88.060  104.375 107.648 1.00 52.92  ? 501 LEU B CG  1 
ATOM   7747 C CD1 . LEU B 1 501 ? 88.267  105.556 108.581 1.00 52.92  ? 501 LEU B CD1 1 
ATOM   7748 C CD2 . LEU B 1 501 ? 89.008  104.484 106.461 1.00 52.92  ? 501 LEU B CD2 1 
ATOM   7749 N N   . ASN B 1 502 ? 89.937  100.743 107.383 1.00 58.93  ? 502 ASN B N   1 
ATOM   7750 C CA  . ASN B 1 502 ? 90.995  100.243 106.510 1.00 58.93  ? 502 ASN B CA  1 
ATOM   7751 C C   . ASN B 1 502 ? 90.575  98.962  105.799 1.00 58.93  ? 502 ASN B C   1 
ATOM   7752 O O   . ASN B 1 502 ? 90.864  98.783  104.610 1.00 58.93  ? 502 ASN B O   1 
ATOM   7753 C CB  . ASN B 1 502 ? 92.273  100.015 107.315 1.00 58.93  ? 502 ASN B CB  1 
ATOM   7754 C CG  . ASN B 1 502 ? 92.868  101.305 107.835 1.00 58.93  ? 502 ASN B CG  1 
ATOM   7755 O OD1 . ASN B 1 502 ? 92.352  102.391 107.571 1.00 58.93  ? 502 ASN B OD1 1 
ATOM   7756 N ND2 . ASN B 1 502 ? 93.963  101.195 108.579 1.00 58.93  ? 502 ASN B ND2 1 
ATOM   7757 N N   . ASP B 1 503 ? 89.895  98.058  106.509 1.00 58.92  ? 503 ASP B N   1 
ATOM   7758 C CA  . ASP B 1 503 ? 89.506  96.791  105.897 1.00 58.92  ? 503 ASP B CA  1 
ATOM   7759 C C   . ASP B 1 503 ? 88.481  96.999  104.790 1.00 58.92  ? 503 ASP B C   1 
ATOM   7760 O O   . ASP B 1 503 ? 88.609  96.419  103.703 1.00 58.92  ? 503 ASP B O   1 
ATOM   7761 C CB  . ASP B 1 503 ? 88.970  95.838  106.965 1.00 58.92  ? 503 ASP B CB  1 
ATOM   7762 C CG  . ASP B 1 503 ? 88.938  94.396  106.497 1.00 58.92  ? 503 ASP B CG  1 
ATOM   7763 O OD1 . ASP B 1 503 ? 89.381  94.121  105.362 1.00 58.92  ? 503 ASP B OD1 1 
ATOM   7764 O OD2 . ASP B 1 503 ? 88.484  93.531  107.274 1.00 58.92  ? 503 ASP B OD2 1 
ATOM   7765 N N   . VAL B 1 504 ? 87.465  97.830  105.031 1.00 59.13  ? 504 VAL B N   1 
ATOM   7766 C CA  . VAL B 1 504 ? 86.481  98.086  103.985 1.00 59.13  ? 504 VAL B CA  1 
ATOM   7767 C C   . VAL B 1 504 ? 87.119  98.852  102.830 1.00 59.13  ? 504 VAL B C   1 
ATOM   7768 O O   . VAL B 1 504 ? 86.798  98.610  101.662 1.00 59.13  ? 504 VAL B O   1 
ATOM   7769 C CB  . VAL B 1 504 ? 85.256  98.822  104.557 1.00 59.13  ? 504 VAL B CB  1 
ATOM   7770 C CG1 . VAL B 1 504 ? 84.257  99.123  103.452 1.00 59.13  ? 504 VAL B CG1 1 
ATOM   7771 C CG2 . VAL B 1 504 ? 84.597  97.984  105.637 1.00 59.13  ? 504 VAL B CG2 1 
ATOM   7772 N N   . SER B 1 505 ? 88.052  99.762  103.130 1.00 61.42  ? 505 SER B N   1 
ATOM   7773 C CA  . SER B 1 505 ? 88.719  100.511 102.069 1.00 61.42  ? 505 SER B CA  1 
ATOM   7774 C C   . SER B 1 505 ? 89.548  99.596  101.175 1.00 61.42  ? 505 SER B C   1 
ATOM   7775 O O   . SER B 1 505 ? 89.566  99.765  99.951  1.00 61.42  ? 505 SER B O   1 
ATOM   7776 C CB  . SER B 1 505 ? 89.596  101.607 102.671 1.00 61.42  ? 505 SER B CB  1 
ATOM   7777 O OG  . SER B 1 505 ? 90.746  101.831 101.875 1.00 61.42  ? 505 SER B OG  1 
ATOM   7778 N N   . GLU B 1 506 ? 90.248  98.625  101.765 1.00 66.65  ? 506 GLU B N   1 
ATOM   7779 C CA  . GLU B 1 506 ? 91.052  97.723  100.949 1.00 66.65  ? 506 GLU B CA  1 
ATOM   7780 C C   . GLU B 1 506 ? 90.187  96.703  100.216 1.00 66.65  ? 506 GLU B C   1 
ATOM   7781 O O   . GLU B 1 506 ? 90.549  96.266  99.118  1.00 66.65  ? 506 GLU B O   1 
ATOM   7782 C CB  . GLU B 1 506 ? 92.119  97.030  101.805 1.00 66.65  ? 506 GLU B CB  1 
ATOM   7783 C CG  . GLU B 1 506 ? 91.613  95.993  102.802 1.00 66.65  ? 506 GLU B CG  1 
ATOM   7784 C CD  . GLU B 1 506 ? 91.536  94.593  102.217 1.00 66.65  ? 506 GLU B CD  1 
ATOM   7785 O OE1 . GLU B 1 506 ? 92.055  94.384  101.101 1.00 66.65  ? 506 GLU B OE1 1 
ATOM   7786 O OE2 . GLU B 1 506 ? 90.954  93.704  102.873 1.00 66.65  ? 506 GLU B OE2 1 
ATOM   7787 N N   . ARG B 1 507 ? 89.048  96.311  100.796 1.00 63.37  ? 507 ARG B N   1 
ATOM   7788 C CA  . ARG B 1 507 ? 88.173  95.365  100.110 1.00 63.37  ? 507 ARG B CA  1 
ATOM   7789 C C   . ARG B 1 507 ? 87.420  96.027  98.961  1.00 63.37  ? 507 ARG B C   1 
ATOM   7790 O O   . ARG B 1 507 ? 87.152  95.385  97.939  1.00 63.37  ? 507 ARG B O   1 
ATOM   7791 C CB  . ARG B 1 507 ? 87.190  94.740  101.101 1.00 63.37  ? 507 ARG B CB  1 
ATOM   7792 C CG  . ARG B 1 507 ? 86.412  93.565  100.533 1.00 63.37  ? 507 ARG B CG  1 
ATOM   7793 C CD  . ARG B 1 507 ? 87.233  92.286  100.540 1.00 63.37  ? 507 ARG B CD  1 
ATOM   7794 N NE  . ARG B 1 507 ? 87.428  91.765  101.886 1.00 63.37  ? 507 ARG B NE  1 
ATOM   7795 C CZ  . ARG B 1 507 ? 86.529  91.051  102.550 1.00 63.37  ? 507 ARG B CZ  1 
ATOM   7796 N NH1 . ARG B 1 507 ? 85.350  90.760  102.024 1.00 63.37  ? 507 ARG B NH1 1 
ATOM   7797 N NH2 . ARG B 1 507 ? 86.821  90.615  103.772 1.00 63.37  ? 507 ARG B NH2 1 
ATOM   7798 N N   . VAL B 1 508 ? 87.072  97.307  99.107  1.00 66.47  ? 508 VAL B N   1 
ATOM   7799 C CA  . VAL B 1 508 ? 86.213  97.957  98.124  1.00 66.47  ? 508 VAL B CA  1 
ATOM   7800 C C   . VAL B 1 508 ? 86.959  98.231  96.822  1.00 66.47  ? 508 VAL B C   1 
ATOM   7801 O O   . VAL B 1 508 ? 86.340  98.312  95.755  1.00 66.47  ? 508 VAL B O   1 
ATOM   7802 C CB  . VAL B 1 508 ? 85.608  99.239  98.730  1.00 66.47  ? 508 VAL B CB  1 
ATOM   7803 C CG1 . VAL B 1 508 ? 86.570  100.412 98.632  1.00 66.47  ? 508 VAL B CG1 1 
ATOM   7804 C CG2 . VAL B 1 508 ? 84.301  99.566  98.055  1.00 66.47  ? 508 VAL B CG2 1 
ATOM   7805 N N   . GLY B 1 509 ? 88.271  98.373  96.875  1.00 77.29  ? 509 GLY B N   1 
ATOM   7806 C CA  . GLY B 1 509 ? 89.012  98.691  95.674  1.00 77.29  ? 509 GLY B CA  1 
ATOM   7807 C C   . GLY B 1 509 ? 89.484  100.135 95.674  1.00 77.29  ? 509 GLY B C   1 
ATOM   7808 O O   . GLY B 1 509 ? 88.929  101.003 96.361  1.00 77.29  ? 509 GLY B O   1 
ATOM   7809 N N   . SER B 1 510 ? 90.533  100.397 94.892  1.00 82.55  ? 510 SER B N   1 
ATOM   7810 C CA  . SER B 1 510 ? 91.098  101.741 94.843  1.00 82.55  ? 510 SER B CA  1 
ATOM   7811 C C   . SER B 1 510 ? 90.183  102.721 94.120  1.00 82.55  ? 510 SER B C   1 
ATOM   7812 O O   . SER B 1 510 ? 90.285  103.933 94.340  1.00 82.55  ? 510 SER B O   1 
ATOM   7813 C CB  . SER B 1 510 ? 92.472  101.708 94.174  1.00 82.55  ? 510 SER B CB  1 
ATOM   7814 O OG  . SER B 1 510 ? 92.988  103.016 94.005  1.00 82.55  ? 510 SER B OG  1 
ATOM   7815 N N   . ASP B 1 511 ? 89.305  102.227 93.244  1.00 87.54  ? 511 ASP B N   1 
ATOM   7816 C CA  . ASP B 1 511 ? 88.454  103.122 92.464  1.00 87.54  ? 511 ASP B CA  1 
ATOM   7817 C C   . ASP B 1 511 ? 87.463  103.876 93.344  1.00 87.54  ? 511 ASP B C   1 
ATOM   7818 O O   . ASP B 1 511 ? 87.216  105.068 93.126  1.00 87.54  ? 511 ASP B O   1 
ATOM   7819 C CB  . ASP B 1 511 ? 87.721  102.335 91.379  1.00 87.54  ? 511 ASP B CB  1 
ATOM   7820 C CG  . ASP B 1 511 ? 87.264  100.971 91.857  1.00 87.54  ? 511 ASP B CG  1 
ATOM   7821 O OD1 . ASP B 1 511 ? 87.416  100.682 93.062  1.00 87.54  ? 511 ASP B OD1 1 
ATOM   7822 O OD2 . ASP B 1 511 ? 86.753  100.188 91.028  1.00 87.54  ? 511 ASP B OD2 1 
ATOM   7823 N N   . ALA B 1 512 ? 86.883  103.205 94.339  1.00 78.33  ? 512 ALA B N   1 
ATOM   7824 C CA  . ALA B 1 512 ? 85.870  103.806 95.199  1.00 78.33  ? 512 ALA B CA  1 
ATOM   7825 C C   . ALA B 1 512 ? 86.403  104.176 96.579  1.00 78.33  ? 512 ALA B C   1 
ATOM   7826 O O   . ALA B 1 512 ? 85.611  104.489 97.479  1.00 78.33  ? 512 ALA B O   1 
ATOM   7827 C CB  . ALA B 1 512 ? 84.675  102.862 95.338  1.00 78.33  ? 512 ALA B CB  1 
ATOM   7828 N N   . SER B 1 513 ? 87.726  104.102 96.734  1.00 69.10  ? 513 SER B N   1 
ATOM   7829 C CA  . SER B 1 513 ? 88.362  104.452 98.027  1.00 69.10  ? 513 SER B CA  1 
ATOM   7830 C C   . SER B 1 513 ? 88.148  105.937 98.351  1.00 69.10  ? 513 SER B C   1 
ATOM   7831 O O   . SER B 1 513 ? 87.900  106.227 99.534  1.00 69.10  ? 513 SER B O   1 
ATOM   7832 C CB  . SER B 1 513 ? 89.811  104.092 98.030  1.00 69.10  ? 513 SER B CB  1 
ATOM   7833 O OG  . SER B 1 513 ? 90.400  104.433 99.277  1.00 69.10  ? 513 SER B OG  1 
ATOM   7834 N N   . PRO B 1 514 ? 88.234  106.901 97.408  1.00 68.48  ? 514 PRO B N   1 
ATOM   7835 C CA  . PRO B 1 514 ? 87.929  108.290 97.729  1.00 68.48  ? 514 PRO B CA  1 
ATOM   7836 C C   . PRO B 1 514 ? 86.438  108.498 97.921  1.00 68.48  ? 514 PRO B C   1 
ATOM   7837 O O   . PRO B 1 514 ? 86.029  109.635 98.211  1.00 68.48  ? 514 PRO B O   1 
ATOM   7838 C CB  . PRO B 1 514 ? 88.455  109.092 96.542  1.00 68.48  ? 514 PRO B CB  1 
ATOM   7839 C CG  . PRO B 1 514 ? 89.321  108.110 95.785  1.00 68.48  ? 514 PRO B CG  1 
ATOM   7840 C CD  . PRO B 1 514 ? 88.704  106.747 96.044  1.00 68.48  ? 514 PRO B CD  1 
ATOM   7841 N N   . PHE B 1 515 ? 85.638  107.450 97.719  1.00 67.18  ? 515 PHE B N   1 
ATOM   7842 C CA  . PHE B 1 515 ? 84.180  107.552 97.994  1.00 67.18  ? 515 PHE B CA  1 
ATOM   7843 C C   . PHE B 1 515 ? 83.969  107.130 99.433  1.00 67.18  ? 515 PHE B C   1 
ATOM   7844 O O   . PHE B 1 515 ? 83.365  107.885 100.216 1.00 67.18  ? 515 PHE B O   1 
ATOM   7845 C CB  . PHE B 1 515 ? 83.350  106.674 97.053  1.00 67.18  ? 515 PHE B CB  1 
ATOM   7846 C CG  . PHE B 1 515 ? 81.862  106.629 97.367  1.00 67.18  ? 515 PHE B CG  1 
ATOM   7847 C CD1 . PHE B 1 515 ? 80.991  107.565 96.826  1.00 67.18  ? 515 PHE B CD1 1 
ATOM   7848 C CD2 . PHE B 1 515 ? 81.337  105.650 98.201  1.00 67.18  ? 515 PHE B CD2 1 
ATOM   7849 C CE1 . PHE B 1 515 ? 79.638  107.521 97.112  1.00 67.18  ? 515 PHE B CE1 1 
ATOM   7850 C CE2 . PHE B 1 515 ? 79.983  105.613 98.485  1.00 67.18  ? 515 PHE B CE2 1 
ATOM   7851 C CZ  . PHE B 1 515 ? 79.137  106.547 97.941  1.00 67.18  ? 515 PHE B CZ  1 
ATOM   7852 N N   . PHE B 1 516 ? 84.479  105.949 99.784  1.00 57.81  ? 516 PHE B N   1 
ATOM   7853 C CA  . PHE B 1 516 ? 84.349  105.477 101.159 1.00 57.81  ? 516 PHE B CA  1 
ATOM   7854 C C   . PHE B 1 516 ? 84.959  106.468 102.143 1.00 57.81  ? 516 PHE B C   1 
ATOM   7855 O O   . PHE B 1 516 ? 84.413  106.681 103.233 1.00 57.81  ? 516 PHE B O   1 
ATOM   7856 C CB  . PHE B 1 516 ? 84.985  104.099 101.322 1.00 57.81  ? 516 PHE B CB  1 
ATOM   7857 C CG  . PHE B 1 516 ? 84.618  103.422 102.612 1.00 57.81  ? 516 PHE B CG  1 
ATOM   7858 C CD1 . PHE B 1 516 ? 83.309  103.043 102.861 1.00 57.81  ? 516 PHE B CD1 1 
ATOM   7859 C CD2 . PHE B 1 516 ? 85.573  103.190 103.589 1.00 57.81  ? 516 PHE B CD2 1 
ATOM   7860 C CE1 . PHE B 1 516 ? 82.961  102.431 104.049 1.00 57.81  ? 516 PHE B CE1 1 
ATOM   7861 C CE2 . PHE B 1 516 ? 85.230  102.578 104.781 1.00 57.81  ? 516 PHE B CE2 1 
ATOM   7862 C CZ  . PHE B 1 516 ? 83.923  102.202 105.012 1.00 57.81  ? 516 PHE B CZ  1 
ATOM   7863 N N   . ALA B 1 517 ? 86.091  107.081 101.784 1.00 54.67  ? 517 ALA B N   1 
ATOM   7864 C CA  . ALA B 1 517 ? 86.696  108.079 102.661 1.00 54.67  ? 517 ALA B CA  1 
ATOM   7865 C C   . ALA B 1 517 ? 85.778  109.282 102.844 1.00 54.67  ? 517 ALA B C   1 
ATOM   7866 O O   . ALA B 1 517 ? 85.661  109.820 103.952 1.00 54.67  ? 517 ALA B O   1 
ATOM   7867 C CB  . ALA B 1 517 ? 88.051  108.515 102.106 1.00 54.67  ? 517 ALA B CB  1 
ATOM   7868 N N   . ALA B 1 518 ? 85.122  109.725 101.768 1.00 51.66  ? 518 ALA B N   1 
ATOM   7869 C CA  . ALA B 1 518 ? 84.170  110.823 101.893 1.00 51.66  ? 518 ALA B CA  1 
ATOM   7870 C C   . ALA B 1 518 ? 82.945  110.410 102.697 1.00 51.66  ? 518 ALA B C   1 
ATOM   7871 O O   . ALA B 1 518 ? 82.360  111.239 103.400 1.00 51.66  ? 518 ALA B O   1 
ATOM   7872 C CB  . ALA B 1 518 ? 83.758  111.326 100.509 1.00 51.66  ? 518 ALA B CB  1 
ATOM   7873 N N   . ALA B 1 519 ? 82.541  109.143 102.607 1.00 49.29  ? 519 ALA B N   1 
ATOM   7874 C CA  . ALA B 1 519 ? 81.405  108.683 103.398 1.00 49.29  ? 519 ALA B CA  1 
ATOM   7875 C C   . ALA B 1 519 ? 81.736  108.615 104.883 1.00 49.29  ? 519 ALA B C   1 
ATOM   7876 O O   . ALA B 1 519 ? 80.858  108.841 105.721 1.00 49.29  ? 519 ALA B O   1 
ATOM   7877 C CB  . ALA B 1 519 ? 80.936  107.317 102.901 1.00 49.29  ? 519 ALA B CB  1 
ATOM   7878 N N   . VAL B 1 520 ? 82.982  108.299 105.226 1.00 46.75  ? 520 VAL B N   1 
ATOM   7879 C CA  . VAL B 1 520 ? 83.345  108.135 106.631 1.00 46.75  ? 520 VAL B CA  1 
ATOM   7880 C C   . VAL B 1 520 ? 83.791  109.447 107.284 1.00 46.75  ? 520 VAL B C   1 
ATOM   7881 O O   . VAL B 1 520 ? 83.572  109.642 108.485 1.00 46.75  ? 520 VAL B O   1 
ATOM   7882 C CB  . VAL B 1 520 ? 84.427  107.047 106.762 1.00 46.75  ? 520 VAL B CB  1 
ATOM   7883 C CG1 . VAL B 1 520 ? 84.873  106.878 108.207 1.00 46.75  ? 520 VAL B CG1 1 
ATOM   7884 C CG2 . VAL B 1 520 ? 83.909  105.726 106.224 1.00 46.75  ? 520 VAL B CG2 1 
ATOM   7885 N N   . ALA B 1 521 ? 84.374  110.368 106.514 1.00 43.22  ? 521 ALA B N   1 
ATOM   7886 C CA  . ALA B 1 521 ? 85.047  111.529 107.100 1.00 43.22  ? 521 ALA B CA  1 
ATOM   7887 C C   . ALA B 1 521 ? 84.158  112.417 107.971 1.00 43.22  ? 521 ALA B C   1 
ATOM   7888 O O   . ALA B 1 521 ? 84.600  112.781 109.074 1.00 43.22  ? 521 ALA B O   1 
ATOM   7889 C CB  . ALA B 1 521 ? 85.722  112.341 105.989 1.00 43.22  ? 521 ALA B CB  1 
ATOM   7890 N N   . PRO B 1 522 ? 82.947  112.829 107.561 1.00 41.41  ? 522 PRO B N   1 
ATOM   7891 C CA  . PRO B 1 522 ? 82.147  113.687 108.457 1.00 41.41  ? 522 PRO B CA  1 
ATOM   7892 C C   . PRO B 1 522 ? 81.778  113.031 109.774 1.00 41.41  ? 522 PRO B C   1 
ATOM   7893 O O   . PRO B 1 522 ? 81.637  113.727 110.786 1.00 41.41  ? 522 PRO B O   1 
ATOM   7894 C CB  . PRO B 1 522 ? 80.898  114.000 107.622 1.00 41.41  ? 522 PRO B CB  1 
ATOM   7895 C CG  . PRO B 1 522 ? 81.320  113.812 106.227 1.00 41.41  ? 522 PRO B CG  1 
ATOM   7896 C CD  . PRO B 1 522 ? 82.265  112.658 106.266 1.00 41.41  ? 522 PRO B CD  1 
ATOM   7897 N N   . ALA B 1 523 ? 81.605  111.709 109.786 1.00 42.32  ? 523 ALA B N   1 
ATOM   7898 C CA  . ALA B 1 523 ? 81.175  111.017 110.997 1.00 42.32  ? 523 ALA B CA  1 
ATOM   7899 C C   . ALA B 1 523 ? 82.239  111.062 112.086 1.00 42.32  ? 523 ALA B C   1 
ATOM   7900 O O   . ALA B 1 523 ? 81.911  111.162 113.276 1.00 42.32  ? 523 ALA B O   1 
ATOM   7901 C CB  . ALA B 1 523 ? 80.821  109.570 110.663 1.00 42.32  ? 523 ALA B CB  1 
ATOM   7902 N N   . TYR B 1 524 ? 83.514  110.975 111.697 1.00 41.24  ? 524 TYR B N   1 
ATOM   7903 C CA  . TYR B 1 524 ? 84.582  110.683 112.648 1.00 41.24  ? 524 TYR B CA  1 
ATOM   7904 C C   . TYR B 1 524 ? 84.721  111.777 113.702 1.00 41.24  ? 524 TYR B C   1 
ATOM   7905 O O   . TYR B 1 524 ? 84.852  111.485 114.895 1.00 41.24  ? 524 TYR B O   1 
ATOM   7906 C CB  . TYR B 1 524 ? 85.899  110.483 111.898 1.00 41.24  ? 524 TYR B CB  1 
ATOM   7907 C CG  . TYR B 1 524 ? 86.819  109.464 112.529 1.00 41.24  ? 524 TYR B CG  1 
ATOM   7908 C CD1 . TYR B 1 524 ? 87.390  109.687 113.773 1.00 41.24  ? 524 TYR B CD1 1 
ATOM   7909 C CD2 . TYR B 1 524 ? 87.113  108.274 111.878 1.00 41.24  ? 524 TYR B CD2 1 
ATOM   7910 C CE1 . TYR B 1 524 ? 88.231  108.754 114.350 1.00 41.24  ? 524 TYR B CE1 1 
ATOM   7911 C CE2 . TYR B 1 524 ? 87.952  107.337 112.447 1.00 41.24  ? 524 TYR B CE2 1 
ATOM   7912 C CZ  . TYR B 1 524 ? 88.507  107.581 113.683 1.00 41.24  ? 524 TYR B CZ  1 
ATOM   7913 O OH  . TYR B 1 524 ? 89.343  106.651 114.255 1.00 41.24  ? 524 TYR B OH  1 
ATOM   7914 N N   . ALA B 1 525 ? 84.692  113.045 113.282 1.00 41.41  ? 525 ALA B N   1 
ATOM   7915 C CA  . ALA B 1 525 ? 84.926  114.142 114.220 1.00 41.41  ? 525 ALA B CA  1 
ATOM   7916 C C   . ALA B 1 525 ? 83.814  114.239 115.260 1.00 41.41  ? 525 ALA B C   1 
ATOM   7917 O O   . ALA B 1 525 ? 84.080  114.322 116.468 1.00 41.41  ? 525 ALA B O   1 
ATOM   7918 C CB  . ALA B 1 525 ? 85.065  115.460 113.457 1.00 41.41  ? 525 ALA B CB  1 
ATOM   7919 N N   . ILE B 1 526 ? 82.558  114.232 114.804 1.00 41.04  ? 526 ILE B N   1 
ATOM   7920 C CA  . ILE B 1 526 ? 81.423  114.321 115.717 1.00 41.04  ? 526 ILE B CA  1 
ATOM   7921 C C   . ILE B 1 526 ? 81.391  113.113 116.643 1.00 41.04  ? 526 ILE B C   1 
ATOM   7922 O O   . ILE B 1 526 ? 81.166  113.244 117.856 1.00 41.04  ? 526 ILE B O   1 
ATOM   7923 C CB  . ILE B 1 526 ? 80.112  114.460 114.922 1.00 41.04  ? 526 ILE B CB  1 
ATOM   7924 C CG1 . ILE B 1 526 ? 80.133  115.733 114.077 1.00 41.04  ? 526 ILE B CG1 1 
ATOM   7925 C CG2 . ILE B 1 526 ? 78.911  114.457 115.855 1.00 41.04  ? 526 ILE B CG2 1 
ATOM   7926 C CD1 . ILE B 1 526 ? 80.432  116.983 114.871 1.00 41.04  ? 526 ILE B CD1 1 
ATOM   7927 N N   . GLY B 1 527 ? 81.624  111.922 116.087 1.00 39.86  ? 527 GLY B N   1 
ATOM   7928 C CA  . GLY B 1 527 ? 81.648  110.726 116.910 1.00 39.86  ? 527 GLY B CA  1 
ATOM   7929 C C   . GLY B 1 527 ? 82.715  110.782 117.985 1.00 39.86  ? 527 GLY B C   1 
ATOM   7930 O O   . GLY B 1 527 ? 82.456  110.468 119.147 1.00 39.86  ? 527 GLY B O   1 
ATOM   7931 N N   . ASN B 1 528 ? 83.927  111.206 117.611 1.00 40.02  ? 528 ASN B N   1 
ATOM   7932 C CA  . ASN B 1 528 ? 85.015  111.297 118.579 1.00 40.02  ? 528 ASN B CA  1 
ATOM   7933 C C   . ASN B 1 528 ? 84.700  112.300 119.680 1.00 40.02  ? 528 ASN B C   1 
ATOM   7934 O O   . ASN B 1 528 ? 84.889  112.009 120.866 1.00 40.02  ? 528 ASN B O   1 
ATOM   7935 C CB  . ASN B 1 528 ? 86.319  111.666 117.874 1.00 40.02  ? 528 ASN B CB  1 
ATOM   7936 C CG  . ASN B 1 528 ? 87.462  110.744 118.245 1.00 40.02  ? 528 ASN B CG  1 
ATOM   7937 O OD1 . ASN B 1 528 ? 87.841  110.648 119.411 1.00 40.02  ? 528 ASN B OD1 1 
ATOM   7938 N ND2 . ASN B 1 528 ? 88.016  110.057 117.255 1.00 40.02  ? 528 ASN B ND2 1 
ATOM   7939 N N   . ILE B 1 529 ? 84.200  113.483 119.308 1.00 42.05  ? 529 ILE B N   1 
ATOM   7940 C CA  . ILE B 1 529 ? 83.933  114.513 120.311 1.00 42.05  ? 529 ILE B CA  1 
ATOM   7941 C C   . ILE B 1 529 ? 82.848  114.052 121.278 1.00 42.05  ? 529 ILE B C   1 
ATOM   7942 O O   . ILE B 1 529 ? 83.000  114.155 122.506 1.00 42.05  ? 529 ILE B O   1 
ATOM   7943 C CB  . ILE B 1 529 ? 83.561  115.842 119.626 1.00 42.05  ? 529 ILE B CB  1 
ATOM   7944 C CG1 . ILE B 1 529 ? 84.820  116.661 119.342 1.00 42.05  ? 529 ILE B CG1 1 
ATOM   7945 C CG2 . ILE B 1 529 ? 82.598  116.653 120.483 1.00 42.05  ? 529 ILE B CG2 1 
ATOM   7946 C CD1 . ILE B 1 529 ? 84.545  117.956 118.610 1.00 42.05  ? 529 ILE B CD1 1 
ATOM   7947 N N   . PHE B 1 530 ? 81.757  113.493 120.749 1.00 44.03  ? 530 PHE B N   1 
ATOM   7948 C CA  . PHE B 1 530 ? 80.651  113.129 121.625 1.00 44.03  ? 530 PHE B CA  1 
ATOM   7949 C C   . PHE B 1 530 ? 80.978  111.897 122.459 1.00 44.03  ? 530 PHE B C   1 
ATOM   7950 O O   . PHE B 1 530 ? 80.569  111.810 123.621 1.00 44.03  ? 530 PHE B O   1 
ATOM   7951 C CB  . PHE B 1 530 ? 79.383  112.912 120.805 1.00 44.03  ? 530 PHE B CB  1 
ATOM   7952 C CG  . PHE B 1 530 ? 78.478  114.109 120.772 1.00 44.03  ? 530 PHE B CG  1 
ATOM   7953 C CD1 . PHE B 1 530 ? 78.756  115.175 119.934 1.00 44.03  ? 530 PHE B CD1 1 
ATOM   7954 C CD2 . PHE B 1 530 ? 77.360  114.176 121.588 1.00 44.03  ? 530 PHE B CD2 1 
ATOM   7955 C CE1 . PHE B 1 530 ? 77.933  116.284 119.902 1.00 44.03  ? 530 PHE B CE1 1 
ATOM   7956 C CE2 . PHE B 1 530 ? 76.533  115.283 121.560 1.00 44.03  ? 530 PHE B CE2 1 
ATOM   7957 C CZ  . PHE B 1 530 ? 76.820  116.338 120.717 1.00 44.03  ? 530 PHE B CZ  1 
ATOM   7958 N N   . LEU B 1 531 ? 81.741  110.951 121.906 1.00 41.56  ? 531 LEU B N   1 
ATOM   7959 C CA  . LEU B 1 531 ? 82.131  109.786 122.687 1.00 41.56  ? 531 LEU B CA  1 
ATOM   7960 C C   . LEU B 1 531 ? 83.143  110.149 123.764 1.00 41.56  ? 531 LEU B C   1 
ATOM   7961 O O   . LEU B 1 531 ? 83.144  109.540 124.840 1.00 41.56  ? 531 LEU B O   1 
ATOM   7962 C CB  . LEU B 1 531 ? 82.693  108.707 121.764 1.00 41.56  ? 531 LEU B CB  1 
ATOM   7963 C CG  . LEU B 1 531 ? 81.645  107.849 121.053 1.00 41.56  ? 531 LEU B CG  1 
ATOM   7964 C CD1 . LEU B 1 531 ? 82.233  106.508 120.652 1.00 41.56  ? 531 LEU B CD1 1 
ATOM   7965 C CD2 . LEU B 1 531 ? 80.398  107.674 121.904 1.00 41.56  ? 531 LEU B CD2 1 
ATOM   7966 N N   . THR B 1 532 ? 84.018  111.123 123.494 1.00 40.33  ? 532 THR B N   1 
ATOM   7967 C CA  . THR B 1 532 ? 84.908  111.618 124.536 1.00 40.33  ? 532 THR B CA  1 
ATOM   7968 C C   . THR B 1 532 ? 84.118  112.287 125.654 1.00 40.33  ? 532 THR B C   1 
ATOM   7969 O O   . THR B 1 532 ? 84.409  112.082 126.838 1.00 40.33  ? 532 THR B O   1 
ATOM   7970 C CB  . THR B 1 532 ? 85.927  112.587 123.937 1.00 40.33  ? 532 THR B CB  1 
ATOM   7971 O OG1 . THR B 1 532 ? 86.708  111.905 122.948 1.00 40.33  ? 532 THR B OG1 1 
ATOM   7972 C CG2 . THR B 1 532 ? 86.852  113.128 125.014 1.00 40.33  ? 532 THR B CG2 1 
ATOM   7973 N N   . LEU B 1 533 ? 83.100  113.072 125.300 1.00 42.88  ? 533 LEU B N   1 
ATOM   7974 C CA  . LEU B 1 533 ? 82.302  113.727 126.332 1.00 42.88  ? 533 LEU B CA  1 
ATOM   7975 C C   . LEU B 1 533 ? 81.370  112.774 127.076 1.00 42.88  ? 533 LEU B C   1 
ATOM   7976 O O   . LEU B 1 533 ? 80.979  113.084 128.205 1.00 42.88  ? 533 LEU B O   1 
ATOM   7977 C CB  . LEU B 1 533 ? 81.482  114.872 125.732 1.00 42.88  ? 533 LEU B CB  1 
ATOM   7978 C CG  . LEU B 1 533 ? 82.274  116.062 125.189 1.00 42.88  ? 533 LEU B CG  1 
ATOM   7979 C CD1 . LEU B 1 533 ? 81.374  117.279 125.056 1.00 42.88  ? 533 LEU B CD1 1 
ATOM   7980 C CD2 . LEU B 1 533 ? 83.466  116.372 126.079 1.00 42.88  ? 533 LEU B CD2 1 
ATOM   7981 N N   . MET B 1 534 ? 81.012  111.634 126.478 1.00 44.61  ? 534 MET B N   1 
ATOM   7982 C CA  . MET B 1 534 ? 80.030  110.738 127.085 1.00 44.61  ? 534 MET B CA  1 
ATOM   7983 C C   . MET B 1 534 ? 80.497  110.172 128.424 1.00 44.61  ? 534 MET B C   1 
ATOM   7984 O O   . MET B 1 534 ? 79.672  109.927 129.314 1.00 44.61  ? 534 MET B O   1 
ATOM   7985 C CB  . MET B 1 534 ? 79.714  109.595 126.117 1.00 44.61  ? 534 MET B CB  1 
ATOM   7986 C CG  . MET B 1 534 ? 78.519  108.745 126.503 1.00 44.61  ? 534 MET B CG  1 
ATOM   7987 S SD  . MET B 1 534 ? 77.598  108.159 125.069 1.00 44.61  ? 534 MET B SD  1 
ATOM   7988 C CE  . MET B 1 534 ? 76.809  109.670 124.527 1.00 44.61  ? 534 MET B CE  1 
ATOM   7989 N N   . GLY B 1 535 ? 81.802  109.966 128.585 1.00 46.04  ? 535 GLY B N   1 
ATOM   7990 C CA  . GLY B 1 535 ? 82.355  109.298 129.743 1.00 46.04  ? 535 GLY B CA  1 
ATOM   7991 C C   . GLY B 1 535 ? 82.095  109.980 131.074 1.00 46.04  ? 535 GLY B C   1 
ATOM   7992 O O   . GLY B 1 535 ? 81.518  109.386 131.995 1.00 46.04  ? 535 GLY B O   1 
ATOM   7993 N N   . PRO B 1 536 ? 82.577  111.221 131.226 1.00 51.41  ? 536 PRO B N   1 
ATOM   7994 C CA  . PRO B 1 536 ? 82.311  111.955 132.477 1.00 51.41  ? 536 PRO B CA  1 
ATOM   7995 C C   . PRO B 1 536 ? 80.835  112.124 132.787 1.00 51.41  ? 536 PRO B C   1 
ATOM   7996 O O   . PRO B 1 536 ? 80.437  112.028 133.956 1.00 51.41  ? 536 PRO B O   1 
ATOM   7997 C CB  . PRO B 1 536 ? 82.993  113.306 132.230 1.00 51.41  ? 536 PRO B CB  1 
ATOM   7998 C CG  . PRO B 1 536 ? 84.084  112.999 131.273 1.00 51.41  ? 536 PRO B CG  1 
ATOM   7999 C CD  . PRO B 1 536 ? 83.535  111.938 130.364 1.00 51.41  ? 536 PRO B CD  1 
ATOM   8000 N N   . ILE B 1 537 ? 80.008  112.374 131.767 1.00 49.80  ? 537 ILE B N   1 
ATOM   8001 C CA  . ILE B 1 537 ? 78.573  112.509 131.995 1.00 49.80  ? 537 ILE B CA  1 
ATOM   8002 C C   . ILE B 1 537 ? 77.999  111.210 132.537 1.00 49.80  ? 537 ILE B C   1 
ATOM   8003 O O   . ILE B 1 537 ? 77.182  111.218 133.466 1.00 49.80  ? 537 ILE B O   1 
ATOM   8004 C CB  . ILE B 1 537 ? 77.856  112.951 130.706 1.00 49.80  ? 537 ILE B CB  1 
ATOM   8005 C CG1 . ILE B 1 537 ? 78.589  114.130 130.065 1.00 49.80  ? 537 ILE B CG1 1 
ATOM   8006 C CG2 . ILE B 1 537 ? 76.408  113.302 130.997 1.00 49.80  ? 537 ILE B CG2 1 
ATOM   8007 C CD1 . ILE B 1 537 ? 78.021  114.546 128.731 1.00 49.80  ? 537 ILE B CD1 1 
ATOM   8008 N N   . PHE B 1 538 ? 78.423  110.076 131.976 1.00 48.94  ? 538 PHE B N   1 
ATOM   8009 C CA  . PHE B 1 538 ? 77.926  108.794 132.461 1.00 48.94  ? 538 PHE B CA  1 
ATOM   8010 C C   . PHE B 1 538 ? 78.384  108.530 133.888 1.00 48.94  ? 538 PHE B C   1 
ATOM   8011 O O   . PHE B 1 538 ? 77.606  108.036 134.717 1.00 48.94  ? 538 PHE B O   1 
ATOM   8012 C CB  . PHE B 1 538 ? 78.383  107.673 131.533 1.00 48.94  ? 538 PHE B CB  1 
ATOM   8013 C CG  . PHE B 1 538 ? 77.275  107.074 130.735 1.00 48.94  ? 538 PHE B CG  1 
ATOM   8014 C CD1 . PHE B 1 538 ? 76.747  107.757 129.657 1.00 48.94  ? 538 PHE B CD1 1 
ATOM   8015 C CD2 . PHE B 1 538 ? 76.740  105.847 131.071 1.00 48.94  ? 538 PHE B CD2 1 
ATOM   8016 C CE1 . PHE B 1 538 ? 75.721  107.220 128.920 1.00 48.94  ? 538 PHE B CE1 1 
ATOM   8017 C CE2 . PHE B 1 538 ? 75.710  105.307 130.335 1.00 48.94  ? 538 PHE B CE2 1 
ATOM   8018 C CZ  . PHE B 1 538 ? 75.199  105.999 129.260 1.00 48.94  ? 538 PHE B CZ  1 
ATOM   8019 N N   . ILE B 1 539 ? 79.644  108.859 134.193 1.00 55.16  ? 539 ILE B N   1 
ATOM   8020 C CA  . ILE B 1 539 ? 80.151  108.645 135.546 1.00 55.16  ? 539 ILE B CA  1 
ATOM   8021 C C   . ILE B 1 539 ? 79.355  109.468 136.549 1.00 55.16  ? 539 ILE B C   1 
ATOM   8022 O O   . ILE B 1 539 ? 78.932  108.961 137.597 1.00 55.16  ? 539 ILE B O   1 
ATOM   8023 C CB  . ILE B 1 539 ? 81.654  108.970 135.610 1.00 55.16  ? 539 ILE B CB  1 
ATOM   8024 C CG1 . ILE B 1 539 ? 82.477  107.781 135.114 1.00 55.16  ? 539 ILE B CG1 1 
ATOM   8025 C CG2 . ILE B 1 539 ? 82.068  109.341 137.018 1.00 55.16  ? 539 ILE B CG2 1 
ATOM   8026 C CD1 . ILE B 1 539 ? 83.939  108.065 135.021 1.00 55.16  ? 539 ILE B CD1 1 
ATOM   8027 N N   . VAL B 1 540 ? 79.100  110.736 136.225 1.00 59.80  ? 540 VAL B N   1 
ATOM   8028 C CA  . VAL B 1 540 ? 78.354  111.599 137.135 1.00 59.80  ? 540 VAL B CA  1 
ATOM   8029 C C   . VAL B 1 540 ? 76.912  111.122 137.271 1.00 59.80  ? 540 VAL B C   1 
ATOM   8030 O O   . VAL B 1 540 ? 76.349  111.113 138.374 1.00 59.80  ? 540 VAL B O   1 
ATOM   8031 C CB  . VAL B 1 540 ? 78.441  113.063 136.671 1.00 59.80  ? 540 VAL B CB  1 
ATOM   8032 C CG1 . VAL B 1 540 ? 77.453  113.928 137.440 1.00 59.80  ? 540 VAL B CG1 1 
ATOM   8033 C CG2 . VAL B 1 540 ? 79.863  113.577 136.865 1.00 59.80  ? 540 VAL B CG2 1 
ATOM   8034 N N   . LEU B 1 541 ? 76.296  110.699 136.164 1.00 58.72  ? 541 LEU B N   1 
ATOM   8035 C CA  . LEU B 1 541 ? 74.892  110.306 136.207 1.00 58.72  ? 541 LEU B CA  1 
ATOM   8036 C C   . LEU B 1 541 ? 74.687  109.031 137.017 1.00 58.72  ? 541 LEU B C   1 
ATOM   8037 O O   . LEU B 1 541 ? 73.791  108.971 137.866 1.00 58.72  ? 541 LEU B O   1 
ATOM   8038 C CB  . LEU B 1 541 ? 74.358  110.135 134.787 1.00 58.72  ? 541 LEU B CB  1 
ATOM   8039 C CG  . LEU B 1 541 ? 73.563  111.329 134.260 1.00 58.72  ? 541 LEU B CG  1 
ATOM   8040 C CD1 . LEU B 1 541 ? 73.200  111.132 132.794 1.00 58.72  ? 541 LEU B CD1 1 
ATOM   8041 C CD2 . LEU B 1 541 ? 72.323  111.550 135.113 1.00 58.72  ? 541 LEU B CD2 1 
ATOM   8042 N N   . LEU B 1 542 ? 75.499  107.999 136.772 1.00 60.15  ? 542 LEU B N   1 
ATOM   8043 C CA  . LEU B 1 542 ? 75.359  106.776 137.557 1.00 60.15  ? 542 LEU B CA  1 
ATOM   8044 C C   . LEU B 1 542 ? 75.893  106.937 138.976 1.00 60.15  ? 542 LEU B C   1 
ATOM   8045 O O   . LEU B 1 542 ? 75.521  106.159 139.861 1.00 60.15  ? 542 LEU B O   1 
ATOM   8046 C CB  . LEU B 1 542 ? 76.022  105.586 136.851 1.00 60.15  ? 542 LEU B CB  1 
ATOM   8047 C CG  . LEU B 1 542 ? 75.425  104.970 135.572 1.00 60.15  ? 542 LEU B CG  1 
ATOM   8048 C CD1 . LEU B 1 542 ? 74.027  104.441 135.884 1.00 60.15  ? 542 LEU B CD1 1 
ATOM   8049 C CD2 . LEU B 1 542 ? 75.390  105.908 134.367 1.00 60.15  ? 542 LEU B CD2 1 
ATOM   8050 N N   . SER B 1 543 ? 76.744  107.927 139.227 1.00 66.83  ? 543 SER B N   1 
ATOM   8051 C CA  . SER B 1 543 ? 77.190  108.166 140.600 1.00 66.83  ? 543 SER B CA  1 
ATOM   8052 C C   . SER B 1 543 ? 76.066  108.809 141.409 1.00 66.83  ? 543 SER B C   1 
ATOM   8053 O O   . SER B 1 543 ? 76.034  108.716 142.636 1.00 66.83  ? 543 SER B O   1 
ATOM   8054 C CB  . SER B 1 543 ? 78.431  109.058 140.634 1.00 66.83  ? 543 SER B CB  1 
ATOM   8055 O OG  . SER B 1 543 ? 78.179  110.301 140.011 1.00 66.83  ? 543 SER B OG  1 
ATOM   8056 O OXT . SER B 1 543 ? 75.161  109.434 140.853 1.00 66.83  ? 543 SER B OXT 1 
HETATM 8057 N N   . ASP C 2 .   ? 125.808 112.223 115.997 1.00 37.80  ? 601 ASP A N   1 
HETATM 8058 C CA  . ASP C 2 .   ? 125.989 112.373 117.434 1.00 37.80  ? 601 ASP A CA  1 
HETATM 8059 C C   . ASP C 2 .   ? 125.938 110.998 118.092 1.00 37.80  ? 601 ASP A C   1 
HETATM 8060 O O   . ASP C 2 .   ? 125.100 110.168 117.747 1.00 37.80  ? 601 ASP A O   1 
HETATM 8061 C CB  . ASP C 2 .   ? 124.917 113.300 118.015 1.00 37.80  ? 601 ASP A CB  1 
HETATM 8062 C CG  . ASP C 2 .   ? 125.050 113.498 119.517 1.00 37.80  ? 601 ASP A CG  1 
HETATM 8063 O OD1 . ASP C 2 .   ? 126.110 113.169 120.088 1.00 37.80  ? 601 ASP A OD1 1 
HETATM 8064 O OD2 . ASP C 2 .   ? 124.082 113.991 120.133 1.00 37.80  ? 601 ASP A OD2 1 
HETATM 8065 O OXT . ASP C 2 .   ? 126.729 110.680 118.979 1.00 37.80  ? 601 ASP A OXT 1 
HETATM 8066 N N   . ASP D 2 .   ? 90.160  103.858 116.087 1.00 37.80  ? 601 ASP B N   1 
HETATM 8067 C CA  . ASP D 2 .   ? 89.978  103.707 117.524 1.00 37.80  ? 601 ASP B CA  1 
HETATM 8068 C C   . ASP D 2 .   ? 90.024  105.082 118.182 1.00 37.80  ? 601 ASP B C   1 
HETATM 8069 O O   . ASP D 2 .   ? 90.860  105.915 117.838 1.00 37.80  ? 601 ASP B O   1 
HETATM 8070 C CB  . ASP D 2 .   ? 91.053  102.784 118.105 1.00 37.80  ? 601 ASP B CB  1 
HETATM 8071 C CG  . ASP D 2 .   ? 90.919  102.585 119.607 1.00 37.80  ? 601 ASP B CG  1 
HETATM 8072 O OD1 . ASP D 2 .   ? 89.858  102.910 120.178 1.00 37.80  ? 601 ASP B OD1 1 
HETATM 8073 O OD2 . ASP D 2 .   ? 91.889  102.095 120.224 1.00 37.80  ? 601 ASP B OD2 1 
HETATM 8074 O OXT . ASP D 2 .   ? 89.232  105.398 119.069 1.00 37.80  ? 601 ASP B OXT 1 
# 
