data_8XXR
# 
_entry.id   8XXR 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XXR         pdb_00008xxr 10.2210/pdb8xxr/pdb 
WWPDB D_1300044457 ?            ?                   
EMDB  EMD-38759    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-15 ? 
2 'Structure model' 1 1 2025-04-09 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.journal_volume'          
7  2 'Structure model' '_citation.page_first'              
8  2 'Structure model' '_citation.page_last'               
9  2 'Structure model' '_citation.pdbx_database_id_DOI'    
10 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 2 'Structure model' '_citation.title'                   
12 2 'Structure model' '_citation.year'                    
13 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XXR 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of CXCR2 bound to CXCL6 (CXCR2-CXCL6-Go Full map)' 
_pdbx_database_related.db_id          EMD-38759 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 arshukla@iitk.ac.in       Arun  Shukla K 'principal investigator/group leader' 0000-0003-2910-8288 
3 nureki@bs.s.u-tokyo.ac.jp Osamu Nureki ? 'principal investigator/group leader' 0000-0003-1813-7008 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Sano, F.K.'   1 0000-0002-8965-788X 
'Saha, S.'     2 0000-0002-0036-4969 
'Sharma, S.'   3 0009-0005-9109-9054 
'Ganguly, M.'  4 0009-0007-6165-3063 
'Shihoya, W.'  5 0000-0003-4813-5740 
'Nureki, O.'   6 0000-0003-1813-7008 
'Shukla, A.K.' 7 0000-0003-2910-8288 
'Banerjee, R.' 8 0000-0002-7751-2317 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mol.Cell 
_citation.journal_id_ASTM           MOCEFL 
_citation.journal_id_CSD            2168 
_citation.journal_id_ISSN           1097-2765 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            85 
_citation.language                  ? 
_citation.page_first                976 
_citation.page_last                 988.e9 
_citation.title                     
'Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.molcel.2025.01.024 
_citation.pdbx_database_id_PubMed   39978339 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Saha, S.'        1  ? 
primary 'Sano, F.K.'      2  ? 
primary 'Sharma, S.'      3  ? 
primary 'Ganguly, M.'     4  ? 
primary 'Mishra, S.'      5  ? 
primary 'Dalal, A.'       6  ? 
primary 'Akasaka, H.'     7  ? 
primary 'Kobayashi, T.A.' 8  ? 
primary 'Zaidi, N.'       9  ? 
primary 'Tiwari, D.'      10 ? 
primary 'Roy, N.'         11 ? 
primary 'Yadav, M.K.'     12 ? 
primary 'Banerjee, N.'    13 ? 
primary 'Saha, S.'        14 ? 
primary 'Mohapatra, S.'   15 ? 
primary 'Itoh, Y.'        16 ? 
primary 'Chevigne, A.'    17 ? 
primary 'Banerjee, R.'    18 ? 
primary 'Shihoya, W.'     19 ? 
primary 'Nureki, O.'      20 ? 
primary 'Shukla, A.K.'    21 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'C-X-C chemokine receptor type 2'                                   46699.609 1 ? ?                                 
? ? 
2 polymer man 'Guanine nucleotide-binding protein G(o) subunit alpha'             27024.762 1 ? G42D,E43N,A227D,G230D,I332A,V335I 
? ? 
3 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  38534.062 1 ? ?                                 
? ? 
4 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143  1 ? ?                                 
? ? 
5 polymer man 'Antibody fragment ScFv16'                                          26466.486 1 ? ?                                 
? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 CXC-R2,CXCR-2             
3 'Transducin beta chain 1' 
4 'G gamma-I'               
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
R ? 
2 'polypeptide(L)' no no 
;MGHHHHHHENLYFQGTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGADNSGKSTIVKQMKIIHGGSGGSGGTTG
IVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVDLSDYNRMHESLMLFDSICNNKFFIDTSIILFLNKKDL
FGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNAQVIFDAVTDIIIANNLRGCGLY
;
;MGHHHHHHENLYFQGTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGADNSGKSTIVKQMKIIHGGSGGSGGTTG
IVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVDLSDYNRMHESLMLFDSICNNKFFIDTSIILFLNKKDL
FGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNAQVIFDAVTDIIIANNLRGCGLY
;
A ? 
3 'polypeptide(L)' no no 
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
B ? 
4 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
5 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELK
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELK
;
S ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   LYS n 
1 4   THR n 
1 5   ILE n 
1 6   ILE n 
1 7   ALA n 
1 8   LEU n 
1 9   SER n 
1 10  TYR n 
1 11  ILE n 
1 12  PHE n 
1 13  CYS n 
1 14  LEU n 
1 15  VAL n 
1 16  PHE n 
1 17  ALA n 
1 18  ASP n 
1 19  TYR n 
1 20  LYS n 
1 21  ASP n 
1 22  ASP n 
1 23  ASP n 
1 24  ASP n 
1 25  ALA n 
1 26  ALA n 
1 27  ASN n 
1 28  PHE n 
1 29  THR n 
1 30  PRO n 
1 31  VAL n 
1 32  ASN n 
1 33  GLY n 
1 34  SER n 
1 35  SER n 
1 36  GLY n 
1 37  ASN n 
1 38  GLN n 
1 39  SER n 
1 40  VAL n 
1 41  ARG n 
1 42  LEU n 
1 43  VAL n 
1 44  THR n 
1 45  SER n 
1 46  SER n 
1 47  SER n 
1 48  LEU n 
1 49  GLU n 
1 50  VAL n 
1 51  LEU n 
1 52  PHE n 
1 53  GLN n 
1 54  GLY n 
1 55  PRO n 
1 56  GLY n 
1 57  SER n 
1 58  GLU n 
1 59  ASP n 
1 60  PHE n 
1 61  ASN n 
1 62  MET n 
1 63  GLU n 
1 64  SER n 
1 65  ASP n 
1 66  SER n 
1 67  PHE n 
1 68  GLU n 
1 69  ASP n 
1 70  PHE n 
1 71  TRP n 
1 72  LYS n 
1 73  GLY n 
1 74  GLU n 
1 75  ASP n 
1 76  LEU n 
1 77  SER n 
1 78  ASN n 
1 79  TYR n 
1 80  SER n 
1 81  TYR n 
1 82  SER n 
1 83  SER n 
1 84  THR n 
1 85  LEU n 
1 86  PRO n 
1 87  PRO n 
1 88  PHE n 
1 89  LEU n 
1 90  LEU n 
1 91  ASP n 
1 92  ALA n 
1 93  ALA n 
1 94  PRO n 
1 95  CYS n 
1 96  GLU n 
1 97  PRO n 
1 98  GLU n 
1 99  SER n 
1 100 LEU n 
1 101 GLU n 
1 102 ILE n 
1 103 ASN n 
1 104 LYS n 
1 105 TYR n 
1 106 PHE n 
1 107 VAL n 
1 108 VAL n 
1 109 ILE n 
1 110 ILE n 
1 111 TYR n 
1 112 ALA n 
1 113 LEU n 
1 114 VAL n 
1 115 PHE n 
1 116 LEU n 
1 117 LEU n 
1 118 SER n 
1 119 LEU n 
1 120 LEU n 
1 121 GLY n 
1 122 ASN n 
1 123 SER n 
1 124 LEU n 
1 125 VAL n 
1 126 MET n 
1 127 LEU n 
1 128 VAL n 
1 129 ILE n 
1 130 LEU n 
1 131 TYR n 
1 132 SER n 
1 133 ARG n 
1 134 VAL n 
1 135 GLY n 
1 136 ARG n 
1 137 SER n 
1 138 VAL n 
1 139 THR n 
1 140 ASP n 
1 141 VAL n 
1 142 TYR n 
1 143 LEU n 
1 144 LEU n 
1 145 ASN n 
1 146 LEU n 
1 147 ALA n 
1 148 LEU n 
1 149 ALA n 
1 150 ASP n 
1 151 LEU n 
1 152 LEU n 
1 153 PHE n 
1 154 ALA n 
1 155 LEU n 
1 156 THR n 
1 157 LEU n 
1 158 PRO n 
1 159 ILE n 
1 160 TRP n 
1 161 ALA n 
1 162 ALA n 
1 163 SER n 
1 164 LYS n 
1 165 VAL n 
1 166 ASN n 
1 167 GLY n 
1 168 TRP n 
1 169 ILE n 
1 170 PHE n 
1 171 GLY n 
1 172 THR n 
1 173 PHE n 
1 174 LEU n 
1 175 CYS n 
1 176 LYS n 
1 177 VAL n 
1 178 VAL n 
1 179 SER n 
1 180 LEU n 
1 181 LEU n 
1 182 LYS n 
1 183 GLU n 
1 184 VAL n 
1 185 ASN n 
1 186 PHE n 
1 187 TYR n 
1 188 SER n 
1 189 GLY n 
1 190 ILE n 
1 191 LEU n 
1 192 LEU n 
1 193 LEU n 
1 194 ALA n 
1 195 CYS n 
1 196 ILE n 
1 197 SER n 
1 198 VAL n 
1 199 ASP n 
1 200 ARG n 
1 201 TYR n 
1 202 LEU n 
1 203 ALA n 
1 204 ILE n 
1 205 VAL n 
1 206 HIS n 
1 207 ALA n 
1 208 THR n 
1 209 ARG n 
1 210 THR n 
1 211 LEU n 
1 212 THR n 
1 213 GLN n 
1 214 LYS n 
1 215 ARG n 
1 216 TYR n 
1 217 LEU n 
1 218 VAL n 
1 219 LYS n 
1 220 PHE n 
1 221 ILE n 
1 222 CYS n 
1 223 LEU n 
1 224 SER n 
1 225 ILE n 
1 226 TRP n 
1 227 GLY n 
1 228 LEU n 
1 229 SER n 
1 230 LEU n 
1 231 LEU n 
1 232 LEU n 
1 233 ALA n 
1 234 LEU n 
1 235 PRO n 
1 236 VAL n 
1 237 LEU n 
1 238 LEU n 
1 239 PHE n 
1 240 ARG n 
1 241 ARG n 
1 242 THR n 
1 243 VAL n 
1 244 TYR n 
1 245 SER n 
1 246 SER n 
1 247 ASN n 
1 248 VAL n 
1 249 SER n 
1 250 PRO n 
1 251 ALA n 
1 252 CYS n 
1 253 TYR n 
1 254 GLU n 
1 255 ASP n 
1 256 MET n 
1 257 GLY n 
1 258 ASN n 
1 259 ASN n 
1 260 THR n 
1 261 ALA n 
1 262 ASN n 
1 263 TRP n 
1 264 ARG n 
1 265 MET n 
1 266 LEU n 
1 267 LEU n 
1 268 ARG n 
1 269 ILE n 
1 270 LEU n 
1 271 PRO n 
1 272 GLN n 
1 273 SER n 
1 274 PHE n 
1 275 GLY n 
1 276 PHE n 
1 277 ILE n 
1 278 VAL n 
1 279 PRO n 
1 280 LEU n 
1 281 LEU n 
1 282 ILE n 
1 283 MET n 
1 284 LEU n 
1 285 PHE n 
1 286 CYS n 
1 287 TYR n 
1 288 GLY n 
1 289 PHE n 
1 290 THR n 
1 291 LEU n 
1 292 ARG n 
1 293 THR n 
1 294 LEU n 
1 295 PHE n 
1 296 LYS n 
1 297 ALA n 
1 298 HIS n 
1 299 MET n 
1 300 GLY n 
1 301 GLN n 
1 302 LYS n 
1 303 HIS n 
1 304 ARG n 
1 305 ALA n 
1 306 MET n 
1 307 ARG n 
1 308 VAL n 
1 309 ILE n 
1 310 PHE n 
1 311 ALA n 
1 312 VAL n 
1 313 VAL n 
1 314 LEU n 
1 315 ILE n 
1 316 PHE n 
1 317 LEU n 
1 318 LEU n 
1 319 CYS n 
1 320 TRP n 
1 321 LEU n 
1 322 PRO n 
1 323 TYR n 
1 324 ASN n 
1 325 LEU n 
1 326 VAL n 
1 327 LEU n 
1 328 LEU n 
1 329 ALA n 
1 330 ASP n 
1 331 THR n 
1 332 LEU n 
1 333 MET n 
1 334 ARG n 
1 335 THR n 
1 336 GLN n 
1 337 VAL n 
1 338 ILE n 
1 339 GLN n 
1 340 GLU n 
1 341 THR n 
1 342 CYS n 
1 343 GLU n 
1 344 ARG n 
1 345 ARG n 
1 346 ASN n 
1 347 HIS n 
1 348 ILE n 
1 349 ASP n 
1 350 ARG n 
1 351 ALA n 
1 352 LEU n 
1 353 ASP n 
1 354 ALA n 
1 355 THR n 
1 356 GLU n 
1 357 ILE n 
1 358 LEU n 
1 359 GLY n 
1 360 ILE n 
1 361 LEU n 
1 362 HIS n 
1 363 SER n 
1 364 CYS n 
1 365 LEU n 
1 366 ASN n 
1 367 PRO n 
1 368 LEU n 
1 369 ILE n 
1 370 TYR n 
1 371 ALA n 
1 372 PHE n 
1 373 ILE n 
1 374 GLY n 
1 375 GLN n 
1 376 LYS n 
1 377 PHE n 
1 378 ARG n 
1 379 HIS n 
1 380 GLY n 
1 381 LEU n 
1 382 LEU n 
1 383 LYS n 
1 384 ILE n 
1 385 LEU n 
1 386 ALA n 
1 387 ILE n 
1 388 HIS n 
1 389 GLY n 
1 390 LEU n 
1 391 ILE n 
1 392 SER n 
1 393 LYS n 
1 394 ASP n 
1 395 SER n 
1 396 LEU n 
1 397 PRO n 
1 398 LYS n 
1 399 ASP n 
1 400 SER n 
1 401 ARG n 
1 402 PRO n 
1 403 SER n 
1 404 PHE n 
1 405 VAL n 
1 406 GLY n 
1 407 SER n 
1 408 SER n 
1 409 SER n 
1 410 GLY n 
1 411 HIS n 
1 412 THR n 
1 413 SER n 
1 414 THR n 
1 415 THR n 
1 416 LEU n 
2 1   MET n 
2 2   GLY n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   HIS n 
2 9   GLU n 
2 10  ASN n 
2 11  LEU n 
2 12  TYR n 
2 13  PHE n 
2 14  GLN n 
2 15  GLY n 
2 16  THR n 
2 17  LEU n 
2 18  SER n 
2 19  ALA n 
2 20  GLU n 
2 21  GLU n 
2 22  ARG n 
2 23  ALA n 
2 24  ALA n 
2 25  LEU n 
2 26  GLU n 
2 27  ARG n 
2 28  SER n 
2 29  LYS n 
2 30  ALA n 
2 31  ILE n 
2 32  GLU n 
2 33  LYS n 
2 34  ASN n 
2 35  LEU n 
2 36  LYS n 
2 37  GLU n 
2 38  ASP n 
2 39  GLY n 
2 40  ILE n 
2 41  SER n 
2 42  ALA n 
2 43  ALA n 
2 44  LYS n 
2 45  ASP n 
2 46  VAL n 
2 47  LYS n 
2 48  LEU n 
2 49  LEU n 
2 50  LEU n 
2 51  LEU n 
2 52  GLY n 
2 53  ALA n 
2 54  ASP n 
2 55  ASN n 
2 56  SER n 
2 57  GLY n 
2 58  LYS n 
2 59  SER n 
2 60  THR n 
2 61  ILE n 
2 62  VAL n 
2 63  LYS n 
2 64  GLN n 
2 65  MET n 
2 66  LYS n 
2 67  ILE n 
2 68  ILE n 
2 69  HIS n 
2 70  GLY n 
2 71  GLY n 
2 72  SER n 
2 73  GLY n 
2 74  GLY n 
2 75  SER n 
2 76  GLY n 
2 77  GLY n 
2 78  THR n 
2 79  THR n 
2 80  GLY n 
2 81  ILE n 
2 82  VAL n 
2 83  GLU n 
2 84  THR n 
2 85  HIS n 
2 86  PHE n 
2 87  THR n 
2 88  PHE n 
2 89  LYS n 
2 90  ASN n 
2 91  LEU n 
2 92  HIS n 
2 93  PHE n 
2 94  ARG n 
2 95  LEU n 
2 96  PHE n 
2 97  ASP n 
2 98  VAL n 
2 99  GLY n 
2 100 GLY n 
2 101 GLN n 
2 102 ARG n 
2 103 SER n 
2 104 GLU n 
2 105 ARG n 
2 106 LYS n 
2 107 LYS n 
2 108 TRP n 
2 109 ILE n 
2 110 HIS n 
2 111 CYS n 
2 112 PHE n 
2 113 GLU n 
2 114 ASP n 
2 115 VAL n 
2 116 THR n 
2 117 ALA n 
2 118 ILE n 
2 119 ILE n 
2 120 PHE n 
2 121 CYS n 
2 122 VAL n 
2 123 ASP n 
2 124 LEU n 
2 125 SER n 
2 126 ASP n 
2 127 TYR n 
2 128 ASN n 
2 129 ARG n 
2 130 MET n 
2 131 HIS n 
2 132 GLU n 
2 133 SER n 
2 134 LEU n 
2 135 MET n 
2 136 LEU n 
2 137 PHE n 
2 138 ASP n 
2 139 SER n 
2 140 ILE n 
2 141 CYS n 
2 142 ASN n 
2 143 ASN n 
2 144 LYS n 
2 145 PHE n 
2 146 PHE n 
2 147 ILE n 
2 148 ASP n 
2 149 THR n 
2 150 SER n 
2 151 ILE n 
2 152 ILE n 
2 153 LEU n 
2 154 PHE n 
2 155 LEU n 
2 156 ASN n 
2 157 LYS n 
2 158 LYS n 
2 159 ASP n 
2 160 LEU n 
2 161 PHE n 
2 162 GLY n 
2 163 GLU n 
2 164 LYS n 
2 165 ILE n 
2 166 LYS n 
2 167 LYS n 
2 168 SER n 
2 169 PRO n 
2 170 LEU n 
2 171 THR n 
2 172 ILE n 
2 173 CYS n 
2 174 PHE n 
2 175 PRO n 
2 176 GLU n 
2 177 TYR n 
2 178 THR n 
2 179 GLY n 
2 180 PRO n 
2 181 ASN n 
2 182 THR n 
2 183 TYR n 
2 184 GLU n 
2 185 ASP n 
2 186 ALA n 
2 187 ALA n 
2 188 ALA n 
2 189 TYR n 
2 190 ILE n 
2 191 GLN n 
2 192 ALA n 
2 193 GLN n 
2 194 PHE n 
2 195 GLU n 
2 196 SER n 
2 197 LYS n 
2 198 ASN n 
2 199 ARG n 
2 200 SER n 
2 201 PRO n 
2 202 ASN n 
2 203 LYS n 
2 204 GLU n 
2 205 ILE n 
2 206 TYR n 
2 207 CYS n 
2 208 HIS n 
2 209 MET n 
2 210 THR n 
2 211 CYS n 
2 212 ALA n 
2 213 THR n 
2 214 ASP n 
2 215 THR n 
2 216 ASN n 
2 217 ASN n 
2 218 ALA n 
2 219 GLN n 
2 220 VAL n 
2 221 ILE n 
2 222 PHE n 
2 223 ASP n 
2 224 ALA n 
2 225 VAL n 
2 226 THR n 
2 227 ASP n 
2 228 ILE n 
2 229 ILE n 
2 230 ILE n 
2 231 ALA n 
2 232 ASN n 
2 233 ASN n 
2 234 LEU n 
2 235 ARG n 
2 236 GLY n 
2 237 CYS n 
2 238 GLY n 
2 239 LEU n 
2 240 TYR n 
3 1   MET n 
3 2   HIS n 
3 3   HIS n 
3 4   HIS n 
3 5   HIS n 
3 6   HIS n 
3 7   HIS n 
3 8   GLY n 
3 9   SER n 
3 10  SER n 
3 11  GLY n 
3 12  SER n 
3 13  GLU n 
3 14  LEU n 
3 15  ASP n 
3 16  GLN n 
3 17  LEU n 
3 18  ARG n 
3 19  GLN n 
3 20  GLU n 
3 21  ALA n 
3 22  GLU n 
3 23  GLN n 
3 24  LEU n 
3 25  LYS n 
3 26  ASN n 
3 27  GLN n 
3 28  ILE n 
3 29  ARG n 
3 30  ASP n 
3 31  ALA n 
3 32  ARG n 
3 33  LYS n 
3 34  ALA n 
3 35  CYS n 
3 36  ALA n 
3 37  ASP n 
3 38  ALA n 
3 39  THR n 
3 40  LEU n 
3 41  SER n 
3 42  GLN n 
3 43  ILE n 
3 44  THR n 
3 45  ASN n 
3 46  ASN n 
3 47  ILE n 
3 48  ASP n 
3 49  PRO n 
3 50  VAL n 
3 51  GLY n 
3 52  ARG n 
3 53  ILE n 
3 54  GLN n 
3 55  MET n 
3 56  ARG n 
3 57  THR n 
3 58  ARG n 
3 59  ARG n 
3 60  THR n 
3 61  LEU n 
3 62  ARG n 
3 63  GLY n 
3 64  HIS n 
3 65  LEU n 
3 66  ALA n 
3 67  LYS n 
3 68  ILE n 
3 69  TYR n 
3 70  ALA n 
3 71  MET n 
3 72  HIS n 
3 73  TRP n 
3 74  GLY n 
3 75  THR n 
3 76  ASP n 
3 77  SER n 
3 78  ARG n 
3 79  LEU n 
3 80  LEU n 
3 81  VAL n 
3 82  SER n 
3 83  ALA n 
3 84  SER n 
3 85  GLN n 
3 86  ASP n 
3 87  GLY n 
3 88  LYS n 
3 89  LEU n 
3 90  ILE n 
3 91  ILE n 
3 92  TRP n 
3 93  ASP n 
3 94  SER n 
3 95  TYR n 
3 96  THR n 
3 97  THR n 
3 98  ASN n 
3 99  LYS n 
3 100 VAL n 
3 101 HIS n 
3 102 ALA n 
3 103 ILE n 
3 104 PRO n 
3 105 LEU n 
3 106 ARG n 
3 107 SER n 
3 108 SER n 
3 109 TRP n 
3 110 VAL n 
3 111 MET n 
3 112 THR n 
3 113 CYS n 
3 114 ALA n 
3 115 TYR n 
3 116 ALA n 
3 117 PRO n 
3 118 SER n 
3 119 GLY n 
3 120 ASN n 
3 121 TYR n 
3 122 VAL n 
3 123 ALA n 
3 124 CYS n 
3 125 GLY n 
3 126 GLY n 
3 127 LEU n 
3 128 ASP n 
3 129 ASN n 
3 130 ILE n 
3 131 CYS n 
3 132 SER n 
3 133 ILE n 
3 134 TYR n 
3 135 ASN n 
3 136 LEU n 
3 137 LYS n 
3 138 THR n 
3 139 ARG n 
3 140 GLU n 
3 141 GLY n 
3 142 ASN n 
3 143 VAL n 
3 144 ARG n 
3 145 VAL n 
3 146 SER n 
3 147 ARG n 
3 148 GLU n 
3 149 LEU n 
3 150 ALA n 
3 151 GLY n 
3 152 HIS n 
3 153 THR n 
3 154 GLY n 
3 155 TYR n 
3 156 LEU n 
3 157 SER n 
3 158 CYS n 
3 159 CYS n 
3 160 ARG n 
3 161 PHE n 
3 162 LEU n 
3 163 ASP n 
3 164 ASP n 
3 165 ASN n 
3 166 GLN n 
3 167 ILE n 
3 168 VAL n 
3 169 THR n 
3 170 SER n 
3 171 SER n 
3 172 GLY n 
3 173 ASP n 
3 174 THR n 
3 175 THR n 
3 176 CYS n 
3 177 ALA n 
3 178 LEU n 
3 179 TRP n 
3 180 ASP n 
3 181 ILE n 
3 182 GLU n 
3 183 THR n 
3 184 GLY n 
3 185 GLN n 
3 186 GLN n 
3 187 THR n 
3 188 THR n 
3 189 THR n 
3 190 PHE n 
3 191 THR n 
3 192 GLY n 
3 193 HIS n 
3 194 THR n 
3 195 GLY n 
3 196 ASP n 
3 197 VAL n 
3 198 MET n 
3 199 SER n 
3 200 LEU n 
3 201 SER n 
3 202 LEU n 
3 203 ALA n 
3 204 PRO n 
3 205 ASP n 
3 206 THR n 
3 207 ARG n 
3 208 LEU n 
3 209 PHE n 
3 210 VAL n 
3 211 SER n 
3 212 GLY n 
3 213 ALA n 
3 214 CYS n 
3 215 ASP n 
3 216 ALA n 
3 217 SER n 
3 218 ALA n 
3 219 LYS n 
3 220 LEU n 
3 221 TRP n 
3 222 ASP n 
3 223 VAL n 
3 224 ARG n 
3 225 GLU n 
3 226 GLY n 
3 227 MET n 
3 228 CYS n 
3 229 ARG n 
3 230 GLN n 
3 231 THR n 
3 232 PHE n 
3 233 THR n 
3 234 GLY n 
3 235 HIS n 
3 236 GLU n 
3 237 SER n 
3 238 ASP n 
3 239 ILE n 
3 240 ASN n 
3 241 ALA n 
3 242 ILE n 
3 243 CYS n 
3 244 PHE n 
3 245 PHE n 
3 246 PRO n 
3 247 ASN n 
3 248 GLY n 
3 249 ASN n 
3 250 ALA n 
3 251 PHE n 
3 252 ALA n 
3 253 THR n 
3 254 GLY n 
3 255 SER n 
3 256 ASP n 
3 257 ASP n 
3 258 ALA n 
3 259 THR n 
3 260 CYS n 
3 261 ARG n 
3 262 LEU n 
3 263 PHE n 
3 264 ASP n 
3 265 LEU n 
3 266 ARG n 
3 267 ALA n 
3 268 ASP n 
3 269 GLN n 
3 270 GLU n 
3 271 LEU n 
3 272 MET n 
3 273 THR n 
3 274 TYR n 
3 275 SER n 
3 276 HIS n 
3 277 ASP n 
3 278 ASN n 
3 279 ILE n 
3 280 ILE n 
3 281 CYS n 
3 282 GLY n 
3 283 ILE n 
3 284 THR n 
3 285 SER n 
3 286 VAL n 
3 287 SER n 
3 288 PHE n 
3 289 SER n 
3 290 LYS n 
3 291 SER n 
3 292 GLY n 
3 293 ARG n 
3 294 LEU n 
3 295 LEU n 
3 296 LEU n 
3 297 ALA n 
3 298 GLY n 
3 299 TYR n 
3 300 ASP n 
3 301 ASP n 
3 302 PHE n 
3 303 ASN n 
3 304 CYS n 
3 305 ASN n 
3 306 VAL n 
3 307 TRP n 
3 308 ASP n 
3 309 ALA n 
3 310 LEU n 
3 311 LYS n 
3 312 ALA n 
3 313 ASP n 
3 314 ARG n 
3 315 ALA n 
3 316 GLY n 
3 317 VAL n 
3 318 LEU n 
3 319 ALA n 
3 320 GLY n 
3 321 HIS n 
3 322 ASP n 
3 323 ASN n 
3 324 ARG n 
3 325 VAL n 
3 326 SER n 
3 327 CYS n 
3 328 LEU n 
3 329 GLY n 
3 330 VAL n 
3 331 THR n 
3 332 ASP n 
3 333 ASP n 
3 334 GLY n 
3 335 MET n 
3 336 ALA n 
3 337 VAL n 
3 338 ALA n 
3 339 THR n 
3 340 GLY n 
3 341 SER n 
3 342 TRP n 
3 343 ASP n 
3 344 SER n 
3 345 PHE n 
3 346 LEU n 
3 347 LYS n 
3 348 ILE n 
3 349 TRP n 
3 350 ASN n 
4 1   MET n 
4 2   ALA n 
4 3   SER n 
4 4   ASN n 
4 5   ASN n 
4 6   THR n 
4 7   ALA n 
4 8   SER n 
4 9   ILE n 
4 10  ALA n 
4 11  GLN n 
4 12  ALA n 
4 13  ARG n 
4 14  LYS n 
4 15  LEU n 
4 16  VAL n 
4 17  GLU n 
4 18  GLN n 
4 19  LEU n 
4 20  LYS n 
4 21  MET n 
4 22  GLU n 
4 23  ALA n 
4 24  ASN n 
4 25  ILE n 
4 26  ASP n 
4 27  ARG n 
4 28  ILE n 
4 29  LYS n 
4 30  VAL n 
4 31  SER n 
4 32  LYS n 
4 33  ALA n 
4 34  ALA n 
4 35  ALA n 
4 36  ASP n 
4 37  LEU n 
4 38  MET n 
4 39  ALA n 
4 40  TYR n 
4 41  CYS n 
4 42  GLU n 
4 43  ALA n 
4 44  HIS n 
4 45  ALA n 
4 46  LYS n 
4 47  GLU n 
4 48  ASP n 
4 49  PRO n 
4 50  LEU n 
4 51  LEU n 
4 52  THR n 
4 53  PRO n 
4 54  VAL n 
4 55  PRO n 
4 56  ALA n 
4 57  SER n 
4 58  GLU n 
4 59  ASN n 
4 60  PRO n 
4 61  PHE n 
4 62  ARG n 
4 63  GLU n 
4 64  LYS n 
4 65  LYS n 
4 66  PHE n 
4 67  PHE n 
4 68  CYS n 
4 69  ALA n 
4 70  ILE n 
4 71  LEU n 
5 1   ASP n 
5 2   VAL n 
5 3   GLN n 
5 4   LEU n 
5 5   VAL n 
5 6   GLU n 
5 7   SER n 
5 8   GLY n 
5 9   GLY n 
5 10  GLY n 
5 11  LEU n 
5 12  VAL n 
5 13  GLN n 
5 14  PRO n 
5 15  GLY n 
5 16  GLY n 
5 17  SER n 
5 18  ARG n 
5 19  LYS n 
5 20  LEU n 
5 21  SER n 
5 22  CYS n 
5 23  SER n 
5 24  ALA n 
5 25  SER n 
5 26  GLY n 
5 27  PHE n 
5 28  ALA n 
5 29  PHE n 
5 30  SER n 
5 31  SER n 
5 32  PHE n 
5 33  GLY n 
5 34  MET n 
5 35  HIS n 
5 36  TRP n 
5 37  VAL n 
5 38  ARG n 
5 39  GLN n 
5 40  ALA n 
5 41  PRO n 
5 42  GLU n 
5 43  LYS n 
5 44  GLY n 
5 45  LEU n 
5 46  GLU n 
5 47  TRP n 
5 48  VAL n 
5 49  ALA n 
5 50  TYR n 
5 51  ILE n 
5 52  SER n 
5 53  SER n 
5 54  GLY n 
5 55  SER n 
5 56  GLY n 
5 57  THR n 
5 58  ILE n 
5 59  TYR n 
5 60  TYR n 
5 61  ALA n 
5 62  ASP n 
5 63  THR n 
5 64  VAL n 
5 65  LYS n 
5 66  GLY n 
5 67  ARG n 
5 68  PHE n 
5 69  THR n 
5 70  ILE n 
5 71  SER n 
5 72  ARG n 
5 73  ASP n 
5 74  ASP n 
5 75  PRO n 
5 76  LYS n 
5 77  ASN n 
5 78  THR n 
5 79  LEU n 
5 80  PHE n 
5 81  LEU n 
5 82  GLN n 
5 83  MET n 
5 84  THR n 
5 85  SER n 
5 86  LEU n 
5 87  ARG n 
5 88  SER n 
5 89  GLU n 
5 90  ASP n 
5 91  THR n 
5 92  ALA n 
5 93  MET n 
5 94  TYR n 
5 95  TYR n 
5 96  CYS n 
5 97  VAL n 
5 98  ARG n 
5 99  SER n 
5 100 ILE n 
5 101 TYR n 
5 102 TYR n 
5 103 TYR n 
5 104 GLY n 
5 105 SER n 
5 106 SER n 
5 107 PRO n 
5 108 PHE n 
5 109 ASP n 
5 110 PHE n 
5 111 TRP n 
5 112 GLY n 
5 113 GLN n 
5 114 GLY n 
5 115 THR n 
5 116 THR n 
5 117 LEU n 
5 118 THR n 
5 119 VAL n 
5 120 SER n 
5 121 SER n 
5 122 GLY n 
5 123 GLY n 
5 124 GLY n 
5 125 GLY n 
5 126 SER n 
5 127 GLY n 
5 128 GLY n 
5 129 GLY n 
5 130 GLY n 
5 131 SER n 
5 132 GLY n 
5 133 GLY n 
5 134 GLY n 
5 135 GLY n 
5 136 SER n 
5 137 ASP n 
5 138 ILE n 
5 139 VAL n 
5 140 MET n 
5 141 THR n 
5 142 GLN n 
5 143 ALA n 
5 144 THR n 
5 145 SER n 
5 146 SER n 
5 147 VAL n 
5 148 PRO n 
5 149 VAL n 
5 150 THR n 
5 151 PRO n 
5 152 GLY n 
5 153 GLU n 
5 154 SER n 
5 155 VAL n 
5 156 SER n 
5 157 ILE n 
5 158 SER n 
5 159 CYS n 
5 160 ARG n 
5 161 SER n 
5 162 SER n 
5 163 LYS n 
5 164 SER n 
5 165 LEU n 
5 166 LEU n 
5 167 HIS n 
5 168 SER n 
5 169 ASN n 
5 170 GLY n 
5 171 ASN n 
5 172 THR n 
5 173 TYR n 
5 174 LEU n 
5 175 TYR n 
5 176 TRP n 
5 177 PHE n 
5 178 LEU n 
5 179 GLN n 
5 180 ARG n 
5 181 PRO n 
5 182 GLY n 
5 183 GLN n 
5 184 SER n 
5 185 PRO n 
5 186 GLN n 
5 187 LEU n 
5 188 LEU n 
5 189 ILE n 
5 190 TYR n 
5 191 ARG n 
5 192 MET n 
5 193 SER n 
5 194 ASN n 
5 195 LEU n 
5 196 ALA n 
5 197 SER n 
5 198 GLY n 
5 199 VAL n 
5 200 PRO n 
5 201 ASP n 
5 202 ARG n 
5 203 PHE n 
5 204 SER n 
5 205 GLY n 
5 206 SER n 
5 207 GLY n 
5 208 SER n 
5 209 GLY n 
5 210 THR n 
5 211 ALA n 
5 212 PHE n 
5 213 THR n 
5 214 LEU n 
5 215 THR n 
5 216 ILE n 
5 217 SER n 
5 218 ARG n 
5 219 LEU n 
5 220 GLU n 
5 221 ALA n 
5 222 GLU n 
5 223 ASP n 
5 224 VAL n 
5 225 GLY n 
5 226 VAL n 
5 227 TYR n 
5 228 TYR n 
5 229 CYS n 
5 230 MET n 
5 231 GLN n 
5 232 HIS n 
5 233 LEU n 
5 234 GLU n 
5 235 TYR n 
5 236 PRO n 
5 237 LEU n 
5 238 THR n 
5 239 PHE n 
5 240 GLY n 
5 241 ALA n 
5 242 GLY n 
5 243 THR n 
5 244 LYS n 
5 245 LEU n 
5 246 GLU n 
5 247 LEU n 
5 248 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1  416 human ? CXCR2 ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1  77  human ? GNAO1 ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 'Escherichia coli'      562 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 2 sample 'Biological sequence' 78 240 human ? GNAO1 ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 'Escherichia coli'      562 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1  350 human ? GNB1  ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1  71  human ? GNG2  ? ? ? ? ? ? 'Homo sapiens' 9606  ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 
7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1  248 ?     ? ?     ? ? ? ? ? ? 'Mus musculus' 10090 ? ? ? ? ? ? ? ? 'Escherichia coli'      562 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -55 ?   ?   ?   R . n 
A 1 2   GLY 2   -54 ?   ?   ?   R . n 
A 1 3   LYS 3   -53 ?   ?   ?   R . n 
A 1 4   THR 4   -52 ?   ?   ?   R . n 
A 1 5   ILE 5   -51 ?   ?   ?   R . n 
A 1 6   ILE 6   -50 ?   ?   ?   R . n 
A 1 7   ALA 7   -49 ?   ?   ?   R . n 
A 1 8   LEU 8   -48 ?   ?   ?   R . n 
A 1 9   SER 9   -47 ?   ?   ?   R . n 
A 1 10  TYR 10  -46 ?   ?   ?   R . n 
A 1 11  ILE 11  -45 ?   ?   ?   R . n 
A 1 12  PHE 12  -44 ?   ?   ?   R . n 
A 1 13  CYS 13  -43 ?   ?   ?   R . n 
A 1 14  LEU 14  -42 ?   ?   ?   R . n 
A 1 15  VAL 15  -41 ?   ?   ?   R . n 
A 1 16  PHE 16  -40 ?   ?   ?   R . n 
A 1 17  ALA 17  -39 ?   ?   ?   R . n 
A 1 18  ASP 18  -38 ?   ?   ?   R . n 
A 1 19  TYR 19  -37 ?   ?   ?   R . n 
A 1 20  LYS 20  -36 ?   ?   ?   R . n 
A 1 21  ASP 21  -35 ?   ?   ?   R . n 
A 1 22  ASP 22  -34 ?   ?   ?   R . n 
A 1 23  ASP 23  -33 ?   ?   ?   R . n 
A 1 24  ASP 24  -32 ?   ?   ?   R . n 
A 1 25  ALA 25  -31 ?   ?   ?   R . n 
A 1 26  ALA 26  -30 ?   ?   ?   R . n 
A 1 27  ASN 27  -29 ?   ?   ?   R . n 
A 1 28  PHE 28  -28 ?   ?   ?   R . n 
A 1 29  THR 29  -27 ?   ?   ?   R . n 
A 1 30  PRO 30  -26 ?   ?   ?   R . n 
A 1 31  VAL 31  -25 ?   ?   ?   R . n 
A 1 32  ASN 32  -24 ?   ?   ?   R . n 
A 1 33  GLY 33  -23 ?   ?   ?   R . n 
A 1 34  SER 34  -22 ?   ?   ?   R . n 
A 1 35  SER 35  -21 ?   ?   ?   R . n 
A 1 36  GLY 36  -20 ?   ?   ?   R . n 
A 1 37  ASN 37  -19 ?   ?   ?   R . n 
A 1 38  GLN 38  -18 ?   ?   ?   R . n 
A 1 39  SER 39  -17 ?   ?   ?   R . n 
A 1 40  VAL 40  -16 ?   ?   ?   R . n 
A 1 41  ARG 41  -15 ?   ?   ?   R . n 
A 1 42  LEU 42  -14 ?   ?   ?   R . n 
A 1 43  VAL 43  -13 ?   ?   ?   R . n 
A 1 44  THR 44  -12 ?   ?   ?   R . n 
A 1 45  SER 45  -11 ?   ?   ?   R . n 
A 1 46  SER 46  -10 ?   ?   ?   R . n 
A 1 47  SER 47  -9  ?   ?   ?   R . n 
A 1 48  LEU 48  -8  ?   ?   ?   R . n 
A 1 49  GLU 49  -7  ?   ?   ?   R . n 
A 1 50  VAL 50  -6  ?   ?   ?   R . n 
A 1 51  LEU 51  -5  ?   ?   ?   R . n 
A 1 52  PHE 52  -4  ?   ?   ?   R . n 
A 1 53  GLN 53  -3  ?   ?   ?   R . n 
A 1 54  GLY 54  -2  ?   ?   ?   R . n 
A 1 55  PRO 55  -1  ?   ?   ?   R . n 
A 1 56  GLY 56  0   ?   ?   ?   R . n 
A 1 57  SER 57  1   ?   ?   ?   R . n 
A 1 58  GLU 58  2   ?   ?   ?   R . n 
A 1 59  ASP 59  3   ?   ?   ?   R . n 
A 1 60  PHE 60  4   ?   ?   ?   R . n 
A 1 61  ASN 61  5   ?   ?   ?   R . n 
A 1 62  MET 62  6   ?   ?   ?   R . n 
A 1 63  GLU 63  7   ?   ?   ?   R . n 
A 1 64  SER 64  8   ?   ?   ?   R . n 
A 1 65  ASP 65  9   ?   ?   ?   R . n 
A 1 66  SER 66  10  ?   ?   ?   R . n 
A 1 67  PHE 67  11  ?   ?   ?   R . n 
A 1 68  GLU 68  12  ?   ?   ?   R . n 
A 1 69  ASP 69  13  ?   ?   ?   R . n 
A 1 70  PHE 70  14  ?   ?   ?   R . n 
A 1 71  TRP 71  15  ?   ?   ?   R . n 
A 1 72  LYS 72  16  ?   ?   ?   R . n 
A 1 73  GLY 73  17  ?   ?   ?   R . n 
A 1 74  GLU 74  18  ?   ?   ?   R . n 
A 1 75  ASP 75  19  ?   ?   ?   R . n 
A 1 76  LEU 76  20  ?   ?   ?   R . n 
A 1 77  SER 77  21  ?   ?   ?   R . n 
A 1 78  ASN 78  22  ?   ?   ?   R . n 
A 1 79  TYR 79  23  ?   ?   ?   R . n 
A 1 80  SER 80  24  ?   ?   ?   R . n 
A 1 81  TYR 81  25  ?   ?   ?   R . n 
A 1 82  SER 82  26  ?   ?   ?   R . n 
A 1 83  SER 83  27  ?   ?   ?   R . n 
A 1 84  THR 84  28  ?   ?   ?   R . n 
A 1 85  LEU 85  29  ?   ?   ?   R . n 
A 1 86  PRO 86  30  ?   ?   ?   R . n 
A 1 87  PRO 87  31  ?   ?   ?   R . n 
A 1 88  PHE 88  32  ?   ?   ?   R . n 
A 1 89  LEU 89  33  ?   ?   ?   R . n 
A 1 90  LEU 90  34  ?   ?   ?   R . n 
A 1 91  ASP 91  35  ?   ?   ?   R . n 
A 1 92  ALA 92  36  ?   ?   ?   R . n 
A 1 93  ALA 93  37  ?   ?   ?   R . n 
A 1 94  PRO 94  38  38  PRO PRO R . n 
A 1 95  CYS 95  39  39  CYS CYS R . n 
A 1 96  GLU 96  40  40  GLU GLU R . n 
A 1 97  PRO 97  41  41  PRO PRO R . n 
A 1 98  GLU 98  42  42  GLU GLU R . n 
A 1 99  SER 99  43  43  SER SER R . n 
A 1 100 LEU 100 44  44  LEU LEU R . n 
A 1 101 GLU 101 45  45  GLU GLU R . n 
A 1 102 ILE 102 46  46  ILE ILE R . n 
A 1 103 ASN 103 47  47  ASN ASN R . n 
A 1 104 LYS 104 48  48  LYS LYS R . n 
A 1 105 TYR 105 49  49  TYR TYR R . n 
A 1 106 PHE 106 50  50  PHE PHE R . n 
A 1 107 VAL 107 51  51  VAL VAL R . n 
A 1 108 VAL 108 52  52  VAL VAL R . n 
A 1 109 ILE 109 53  53  ILE ILE R . n 
A 1 110 ILE 110 54  54  ILE ILE R . n 
A 1 111 TYR 111 55  55  TYR TYR R . n 
A 1 112 ALA 112 56  56  ALA ALA R . n 
A 1 113 LEU 113 57  57  LEU LEU R . n 
A 1 114 VAL 114 58  58  VAL VAL R . n 
A 1 115 PHE 115 59  59  PHE PHE R . n 
A 1 116 LEU 116 60  60  LEU LEU R . n 
A 1 117 LEU 117 61  61  LEU LEU R . n 
A 1 118 SER 118 62  62  SER SER R . n 
A 1 119 LEU 119 63  63  LEU LEU R . n 
A 1 120 LEU 120 64  64  LEU LEU R . n 
A 1 121 GLY 121 65  65  GLY GLY R . n 
A 1 122 ASN 122 66  66  ASN ASN R . n 
A 1 123 SER 123 67  67  SER SER R . n 
A 1 124 LEU 124 68  68  LEU LEU R . n 
A 1 125 VAL 125 69  69  VAL VAL R . n 
A 1 126 MET 126 70  70  MET MET R . n 
A 1 127 LEU 127 71  71  LEU LEU R . n 
A 1 128 VAL 128 72  72  VAL VAL R . n 
A 1 129 ILE 129 73  73  ILE ILE R . n 
A 1 130 LEU 130 74  74  LEU LEU R . n 
A 1 131 TYR 131 75  75  TYR TYR R . n 
A 1 132 SER 132 76  76  SER SER R . n 
A 1 133 ARG 133 77  77  ARG ARG R . n 
A 1 134 VAL 134 78  78  VAL VAL R . n 
A 1 135 GLY 135 79  79  GLY GLY R . n 
A 1 136 ARG 136 80  80  ARG ARG R . n 
A 1 137 SER 137 81  81  SER SER R . n 
A 1 138 VAL 138 82  82  VAL VAL R . n 
A 1 139 THR 139 83  83  THR THR R . n 
A 1 140 ASP 140 84  84  ASP ASP R . n 
A 1 141 VAL 141 85  85  VAL VAL R . n 
A 1 142 TYR 142 86  86  TYR TYR R . n 
A 1 143 LEU 143 87  87  LEU LEU R . n 
A 1 144 LEU 144 88  88  LEU LEU R . n 
A 1 145 ASN 145 89  89  ASN ASN R . n 
A 1 146 LEU 146 90  90  LEU LEU R . n 
A 1 147 ALA 147 91  91  ALA ALA R . n 
A 1 148 LEU 148 92  92  LEU LEU R . n 
A 1 149 ALA 149 93  93  ALA ALA R . n 
A 1 150 ASP 150 94  94  ASP ASP R . n 
A 1 151 LEU 151 95  95  LEU LEU R . n 
A 1 152 LEU 152 96  96  LEU LEU R . n 
A 1 153 PHE 153 97  97  PHE PHE R . n 
A 1 154 ALA 154 98  98  ALA ALA R . n 
A 1 155 LEU 155 99  99  LEU LEU R . n 
A 1 156 THR 156 100 100 THR THR R . n 
A 1 157 LEU 157 101 101 LEU LEU R . n 
A 1 158 PRO 158 102 102 PRO PRO R . n 
A 1 159 ILE 159 103 103 ILE ILE R . n 
A 1 160 TRP 160 104 104 TRP TRP R . n 
A 1 161 ALA 161 105 105 ALA ALA R . n 
A 1 162 ALA 162 106 106 ALA ALA R . n 
A 1 163 SER 163 107 107 SER SER R . n 
A 1 164 LYS 164 108 108 LYS LYS R . n 
A 1 165 VAL 165 109 109 VAL VAL R . n 
A 1 166 ASN 166 110 110 ASN ASN R . n 
A 1 167 GLY 167 111 111 GLY GLY R . n 
A 1 168 TRP 168 112 112 TRP TRP R . n 
A 1 169 ILE 169 113 113 ILE ILE R . n 
A 1 170 PHE 170 114 114 PHE PHE R . n 
A 1 171 GLY 171 115 115 GLY GLY R . n 
A 1 172 THR 172 116 116 THR THR R . n 
A 1 173 PHE 173 117 117 PHE PHE R . n 
A 1 174 LEU 174 118 118 LEU LEU R . n 
A 1 175 CYS 175 119 119 CYS CYS R . n 
A 1 176 LYS 176 120 120 LYS LYS R . n 
A 1 177 VAL 177 121 121 VAL VAL R . n 
A 1 178 VAL 178 122 122 VAL VAL R . n 
A 1 179 SER 179 123 123 SER SER R . n 
A 1 180 LEU 180 124 124 LEU LEU R . n 
A 1 181 LEU 181 125 125 LEU LEU R . n 
A 1 182 LYS 182 126 126 LYS LYS R . n 
A 1 183 GLU 183 127 127 GLU GLU R . n 
A 1 184 VAL 184 128 128 VAL VAL R . n 
A 1 185 ASN 185 129 129 ASN ASN R . n 
A 1 186 PHE 186 130 130 PHE PHE R . n 
A 1 187 TYR 187 131 131 TYR TYR R . n 
A 1 188 SER 188 132 132 SER SER R . n 
A 1 189 GLY 189 133 133 GLY GLY R . n 
A 1 190 ILE 190 134 134 ILE ILE R . n 
A 1 191 LEU 191 135 135 LEU LEU R . n 
A 1 192 LEU 192 136 136 LEU LEU R . n 
A 1 193 LEU 193 137 137 LEU LEU R . n 
A 1 194 ALA 194 138 138 ALA ALA R . n 
A 1 195 CYS 195 139 139 CYS CYS R . n 
A 1 196 ILE 196 140 140 ILE ILE R . n 
A 1 197 SER 197 141 141 SER SER R . n 
A 1 198 VAL 198 142 142 VAL VAL R . n 
A 1 199 ASP 199 143 143 ASP ASP R . n 
A 1 200 ARG 200 144 144 ARG ARG R . n 
A 1 201 TYR 201 145 145 TYR TYR R . n 
A 1 202 LEU 202 146 146 LEU LEU R . n 
A 1 203 ALA 203 147 147 ALA ALA R . n 
A 1 204 ILE 204 148 148 ILE ILE R . n 
A 1 205 VAL 205 149 149 VAL VAL R . n 
A 1 206 HIS 206 150 150 HIS HIS R . n 
A 1 207 ALA 207 151 151 ALA ALA R . n 
A 1 208 THR 208 152 152 THR THR R . n 
A 1 209 ARG 209 153 153 ARG ARG R . n 
A 1 210 THR 210 154 154 THR THR R . n 
A 1 211 LEU 211 155 155 LEU LEU R . n 
A 1 212 THR 212 156 156 THR THR R . n 
A 1 213 GLN 213 157 157 GLN GLN R . n 
A 1 214 LYS 214 158 158 LYS LYS R . n 
A 1 215 ARG 215 159 159 ARG ARG R . n 
A 1 216 TYR 216 160 160 TYR TYR R . n 
A 1 217 LEU 217 161 161 LEU LEU R . n 
A 1 218 VAL 218 162 162 VAL VAL R . n 
A 1 219 LYS 219 163 163 LYS LYS R . n 
A 1 220 PHE 220 164 164 PHE PHE R . n 
A 1 221 ILE 221 165 165 ILE ILE R . n 
A 1 222 CYS 222 166 166 CYS CYS R . n 
A 1 223 LEU 223 167 167 LEU LEU R . n 
A 1 224 SER 224 168 168 SER SER R . n 
A 1 225 ILE 225 169 169 ILE ILE R . n 
A 1 226 TRP 226 170 170 TRP TRP R . n 
A 1 227 GLY 227 171 171 GLY GLY R . n 
A 1 228 LEU 228 172 172 LEU LEU R . n 
A 1 229 SER 229 173 173 SER SER R . n 
A 1 230 LEU 230 174 174 LEU LEU R . n 
A 1 231 LEU 231 175 175 LEU LEU R . n 
A 1 232 LEU 232 176 176 LEU LEU R . n 
A 1 233 ALA 233 177 177 ALA ALA R . n 
A 1 234 LEU 234 178 178 LEU LEU R . n 
A 1 235 PRO 235 179 179 PRO PRO R . n 
A 1 236 VAL 236 180 180 VAL VAL R . n 
A 1 237 LEU 237 181 181 LEU LEU R . n 
A 1 238 LEU 238 182 182 LEU LEU R . n 
A 1 239 PHE 239 183 183 PHE PHE R . n 
A 1 240 ARG 240 184 184 ARG ARG R . n 
A 1 241 ARG 241 185 185 ARG ARG R . n 
A 1 242 THR 242 186 186 THR THR R . n 
A 1 243 VAL 243 187 187 VAL VAL R . n 
A 1 244 TYR 244 188 188 TYR TYR R . n 
A 1 245 SER 245 189 189 SER SER R . n 
A 1 246 SER 246 190 190 SER SER R . n 
A 1 247 ASN 247 191 191 ASN ASN R . n 
A 1 248 VAL 248 192 192 VAL VAL R . n 
A 1 249 SER 249 193 193 SER SER R . n 
A 1 250 PRO 250 194 194 PRO PRO R . n 
A 1 251 ALA 251 195 195 ALA ALA R . n 
A 1 252 CYS 252 196 196 CYS CYS R . n 
A 1 253 TYR 253 197 197 TYR TYR R . n 
A 1 254 GLU 254 198 198 GLU GLU R . n 
A 1 255 ASP 255 199 199 ASP ASP R . n 
A 1 256 MET 256 200 200 MET MET R . n 
A 1 257 GLY 257 201 201 GLY GLY R . n 
A 1 258 ASN 258 202 202 ASN ASN R . n 
A 1 259 ASN 259 203 203 ASN ASN R . n 
A 1 260 THR 260 204 204 THR THR R . n 
A 1 261 ALA 261 205 205 ALA ALA R . n 
A 1 262 ASN 262 206 206 ASN ASN R . n 
A 1 263 TRP 263 207 207 TRP TRP R . n 
A 1 264 ARG 264 208 208 ARG ARG R . n 
A 1 265 MET 265 209 209 MET MET R . n 
A 1 266 LEU 266 210 210 LEU LEU R . n 
A 1 267 LEU 267 211 211 LEU LEU R . n 
A 1 268 ARG 268 212 212 ARG ARG R . n 
A 1 269 ILE 269 213 213 ILE ILE R . n 
A 1 270 LEU 270 214 214 LEU LEU R . n 
A 1 271 PRO 271 215 215 PRO PRO R . n 
A 1 272 GLN 272 216 216 GLN GLN R . n 
A 1 273 SER 273 217 217 SER SER R . n 
A 1 274 PHE 274 218 218 PHE PHE R . n 
A 1 275 GLY 275 219 219 GLY GLY R . n 
A 1 276 PHE 276 220 220 PHE PHE R . n 
A 1 277 ILE 277 221 221 ILE ILE R . n 
A 1 278 VAL 278 222 222 VAL VAL R . n 
A 1 279 PRO 279 223 223 PRO PRO R . n 
A 1 280 LEU 280 224 224 LEU LEU R . n 
A 1 281 LEU 281 225 225 LEU LEU R . n 
A 1 282 ILE 282 226 226 ILE ILE R . n 
A 1 283 MET 283 227 227 MET MET R . n 
A 1 284 LEU 284 228 228 LEU LEU R . n 
A 1 285 PHE 285 229 229 PHE PHE R . n 
A 1 286 CYS 286 230 230 CYS CYS R . n 
A 1 287 TYR 287 231 231 TYR TYR R . n 
A 1 288 GLY 288 232 232 GLY GLY R . n 
A 1 289 PHE 289 233 233 PHE PHE R . n 
A 1 290 THR 290 234 234 THR THR R . n 
A 1 291 LEU 291 235 235 LEU LEU R . n 
A 1 292 ARG 292 236 236 ARG ARG R . n 
A 1 293 THR 293 237 237 THR THR R . n 
A 1 294 LEU 294 238 238 LEU LEU R . n 
A 1 295 PHE 295 239 239 PHE PHE R . n 
A 1 296 LYS 296 240 240 LYS LYS R . n 
A 1 297 ALA 297 241 241 ALA ALA R . n 
A 1 298 HIS 298 242 242 HIS HIS R . n 
A 1 299 MET 299 243 243 MET MET R . n 
A 1 300 GLY 300 244 244 GLY GLY R . n 
A 1 301 GLN 301 245 245 GLN GLN R . n 
A 1 302 LYS 302 246 246 LYS LYS R . n 
A 1 303 HIS 303 247 247 HIS HIS R . n 
A 1 304 ARG 304 248 248 ARG ARG R . n 
A 1 305 ALA 305 249 249 ALA ALA R . n 
A 1 306 MET 306 250 250 MET MET R . n 
A 1 307 ARG 307 251 251 ARG ARG R . n 
A 1 308 VAL 308 252 252 VAL VAL R . n 
A 1 309 ILE 309 253 253 ILE ILE R . n 
A 1 310 PHE 310 254 254 PHE PHE R . n 
A 1 311 ALA 311 255 255 ALA ALA R . n 
A 1 312 VAL 312 256 256 VAL VAL R . n 
A 1 313 VAL 313 257 257 VAL VAL R . n 
A 1 314 LEU 314 258 258 LEU LEU R . n 
A 1 315 ILE 315 259 259 ILE ILE R . n 
A 1 316 PHE 316 260 260 PHE PHE R . n 
A 1 317 LEU 317 261 261 LEU LEU R . n 
A 1 318 LEU 318 262 262 LEU LEU R . n 
A 1 319 CYS 319 263 263 CYS CYS R . n 
A 1 320 TRP 320 264 264 TRP TRP R . n 
A 1 321 LEU 321 265 265 LEU LEU R . n 
A 1 322 PRO 322 266 266 PRO PRO R . n 
A 1 323 TYR 323 267 267 TYR TYR R . n 
A 1 324 ASN 324 268 268 ASN ASN R . n 
A 1 325 LEU 325 269 269 LEU LEU R . n 
A 1 326 VAL 326 270 270 VAL VAL R . n 
A 1 327 LEU 327 271 271 LEU LEU R . n 
A 1 328 LEU 328 272 272 LEU LEU R . n 
A 1 329 ALA 329 273 273 ALA ALA R . n 
A 1 330 ASP 330 274 274 ASP ASP R . n 
A 1 331 THR 331 275 275 THR THR R . n 
A 1 332 LEU 332 276 276 LEU LEU R . n 
A 1 333 MET 333 277 277 MET MET R . n 
A 1 334 ARG 334 278 278 ARG ARG R . n 
A 1 335 THR 335 279 279 THR THR R . n 
A 1 336 GLN 336 280 280 GLN GLN R . n 
A 1 337 VAL 337 281 281 VAL VAL R . n 
A 1 338 ILE 338 282 282 ILE ILE R . n 
A 1 339 GLN 339 283 283 GLN GLN R . n 
A 1 340 GLU 340 284 284 GLU GLU R . n 
A 1 341 THR 341 285 285 THR THR R . n 
A 1 342 CYS 342 286 286 CYS CYS R . n 
A 1 343 GLU 343 287 287 GLU GLU R . n 
A 1 344 ARG 344 288 288 ARG ARG R . n 
A 1 345 ARG 345 289 289 ARG ARG R . n 
A 1 346 ASN 346 290 290 ASN ASN R . n 
A 1 347 HIS 347 291 291 HIS HIS R . n 
A 1 348 ILE 348 292 292 ILE ILE R . n 
A 1 349 ASP 349 293 293 ASP ASP R . n 
A 1 350 ARG 350 294 294 ARG ARG R . n 
A 1 351 ALA 351 295 295 ALA ALA R . n 
A 1 352 LEU 352 296 296 LEU LEU R . n 
A 1 353 ASP 353 297 297 ASP ASP R . n 
A 1 354 ALA 354 298 298 ALA ALA R . n 
A 1 355 THR 355 299 299 THR THR R . n 
A 1 356 GLU 356 300 300 GLU GLU R . n 
A 1 357 ILE 357 301 301 ILE ILE R . n 
A 1 358 LEU 358 302 302 LEU LEU R . n 
A 1 359 GLY 359 303 303 GLY GLY R . n 
A 1 360 ILE 360 304 304 ILE ILE R . n 
A 1 361 LEU 361 305 305 LEU LEU R . n 
A 1 362 HIS 362 306 306 HIS HIS R . n 
A 1 363 SER 363 307 307 SER SER R . n 
A 1 364 CYS 364 308 308 CYS CYS R . n 
A 1 365 LEU 365 309 309 LEU LEU R . n 
A 1 366 ASN 366 310 310 ASN ASN R . n 
A 1 367 PRO 367 311 311 PRO PRO R . n 
A 1 368 LEU 368 312 312 LEU LEU R . n 
A 1 369 ILE 369 313 313 ILE ILE R . n 
A 1 370 TYR 370 314 314 TYR TYR R . n 
A 1 371 ALA 371 315 315 ALA ALA R . n 
A 1 372 PHE 372 316 316 PHE PHE R . n 
A 1 373 ILE 373 317 317 ILE ILE R . n 
A 1 374 GLY 374 318 318 GLY GLY R . n 
A 1 375 GLN 375 319 319 GLN GLN R . n 
A 1 376 LYS 376 320 320 LYS LYS R . n 
A 1 377 PHE 377 321 321 PHE PHE R . n 
A 1 378 ARG 378 322 322 ARG ARG R . n 
A 1 379 HIS 379 323 323 HIS HIS R . n 
A 1 380 GLY 380 324 324 GLY GLY R . n 
A 1 381 LEU 381 325 325 LEU LEU R . n 
A 1 382 LEU 382 326 326 LEU LEU R . n 
A 1 383 LYS 383 327 327 LYS LYS R . n 
A 1 384 ILE 384 328 328 ILE ILE R . n 
A 1 385 LEU 385 329 329 LEU LEU R . n 
A 1 386 ALA 386 330 330 ALA ALA R . n 
A 1 387 ILE 387 331 ?   ?   ?   R . n 
A 1 388 HIS 388 332 ?   ?   ?   R . n 
A 1 389 GLY 389 333 ?   ?   ?   R . n 
A 1 390 LEU 390 334 ?   ?   ?   R . n 
A 1 391 ILE 391 335 ?   ?   ?   R . n 
A 1 392 SER 392 336 ?   ?   ?   R . n 
A 1 393 LYS 393 337 ?   ?   ?   R . n 
A 1 394 ASP 394 338 ?   ?   ?   R . n 
A 1 395 SER 395 339 ?   ?   ?   R . n 
A 1 396 LEU 396 340 ?   ?   ?   R . n 
A 1 397 PRO 397 341 ?   ?   ?   R . n 
A 1 398 LYS 398 342 ?   ?   ?   R . n 
A 1 399 ASP 399 343 ?   ?   ?   R . n 
A 1 400 SER 400 344 ?   ?   ?   R . n 
A 1 401 ARG 401 345 ?   ?   ?   R . n 
A 1 402 PRO 402 346 ?   ?   ?   R . n 
A 1 403 SER 403 347 ?   ?   ?   R . n 
A 1 404 PHE 404 348 ?   ?   ?   R . n 
A 1 405 VAL 405 349 ?   ?   ?   R . n 
A 1 406 GLY 406 350 ?   ?   ?   R . n 
A 1 407 SER 407 351 ?   ?   ?   R . n 
A 1 408 SER 408 352 ?   ?   ?   R . n 
A 1 409 SER 409 353 ?   ?   ?   R . n 
A 1 410 GLY 410 354 ?   ?   ?   R . n 
A 1 411 HIS 411 355 ?   ?   ?   R . n 
A 1 412 THR 412 356 ?   ?   ?   R . n 
A 1 413 SER 413 357 ?   ?   ?   R . n 
A 1 414 THR 414 358 ?   ?   ?   R . n 
A 1 415 THR 415 359 ?   ?   ?   R . n 
A 1 416 LEU 416 360 ?   ?   ?   R . n 
B 2 1   MET 1   -11 ?   ?   ?   A . n 
B 2 2   GLY 2   -10 ?   ?   ?   A . n 
B 2 3   HIS 3   -9  ?   ?   ?   A . n 
B 2 4   HIS 4   -8  ?   ?   ?   A . n 
B 2 5   HIS 5   -7  ?   ?   ?   A . n 
B 2 6   HIS 6   -6  ?   ?   ?   A . n 
B 2 7   HIS 7   -5  ?   ?   ?   A . n 
B 2 8   HIS 8   -4  ?   ?   ?   A . n 
B 2 9   GLU 9   -3  ?   ?   ?   A . n 
B 2 10  ASN 10  -2  ?   ?   ?   A . n 
B 2 11  LEU 11  -1  ?   ?   ?   A . n 
B 2 12  TYR 12  0   ?   ?   ?   A . n 
B 2 13  PHE 13  1   ?   ?   ?   A . n 
B 2 14  GLN 14  2   ?   ?   ?   A . n 
B 2 15  GLY 15  3   ?   ?   ?   A . n 
B 2 16  THR 16  4   4   THR THR A . n 
B 2 17  LEU 17  5   5   LEU LEU A . n 
B 2 18  SER 18  6   6   SER SER A . n 
B 2 19  ALA 19  7   7   ALA ALA A . n 
B 2 20  GLU 20  8   8   GLU GLU A . n 
B 2 21  GLU 21  9   9   GLU GLU A . n 
B 2 22  ARG 22  10  10  ARG ARG A . n 
B 2 23  ALA 23  11  11  ALA ALA A . n 
B 2 24  ALA 24  12  12  ALA ALA A . n 
B 2 25  LEU 25  13  13  LEU LEU A . n 
B 2 26  GLU 26  14  14  GLU GLU A . n 
B 2 27  ARG 27  15  15  ARG ARG A . n 
B 2 28  SER 28  16  16  SER SER A . n 
B 2 29  LYS 29  17  17  LYS LYS A . n 
B 2 30  ALA 30  18  18  ALA ALA A . n 
B 2 31  ILE 31  19  19  ILE ILE A . n 
B 2 32  GLU 32  20  20  GLU GLU A . n 
B 2 33  LYS 33  21  21  LYS LYS A . n 
B 2 34  ASN 34  22  22  ASN ASN A . n 
B 2 35  LEU 35  23  23  LEU LEU A . n 
B 2 36  LYS 36  24  24  LYS LYS A . n 
B 2 37  GLU 37  25  25  GLU GLU A . n 
B 2 38  ASP 38  26  26  ASP ASP A . n 
B 2 39  GLY 39  27  27  GLY GLY A . n 
B 2 40  ILE 40  28  28  ILE ILE A . n 
B 2 41  SER 41  29  29  SER SER A . n 
B 2 42  ALA 42  30  30  ALA ALA A . n 
B 2 43  ALA 43  31  31  ALA ALA A . n 
B 2 44  LYS 44  32  32  LYS LYS A . n 
B 2 45  ASP 45  33  33  ASP ASP A . n 
B 2 46  VAL 46  34  34  VAL VAL A . n 
B 2 47  LYS 47  35  35  LYS LYS A . n 
B 2 48  LEU 48  36  36  LEU LEU A . n 
B 2 49  LEU 49  37  37  LEU LEU A . n 
B 2 50  LEU 50  38  38  LEU LEU A . n 
B 2 51  LEU 51  39  39  LEU LEU A . n 
B 2 52  GLY 52  40  40  GLY GLY A . n 
B 2 53  ALA 53  41  41  ALA ALA A . n 
B 2 54  ASP 54  42  42  ASP ASP A . n 
B 2 55  ASN 55  43  43  ASN ASN A . n 
B 2 56  SER 56  44  44  SER SER A . n 
B 2 57  GLY 57  45  45  GLY GLY A . n 
B 2 58  LYS 58  46  46  LYS LYS A . n 
B 2 59  SER 59  47  47  SER SER A . n 
B 2 60  THR 60  48  48  THR THR A . n 
B 2 61  ILE 61  49  49  ILE ILE A . n 
B 2 62  VAL 62  50  50  VAL VAL A . n 
B 2 63  LYS 63  51  51  LYS LYS A . n 
B 2 64  GLN 64  52  52  GLN GLN A . n 
B 2 65  MET 65  53  53  MET MET A . n 
B 2 66  LYS 66  54  54  LYS LYS A . n 
B 2 67  ILE 67  55  55  ILE ILE A . n 
B 2 68  ILE 68  56  56  ILE ILE A . n 
B 2 69  HIS 69  173 ?   ?   ?   A . n 
B 2 70  GLY 70  174 ?   ?   ?   A . n 
B 2 71  GLY 71  175 ?   ?   ?   A . n 
B 2 72  SER 72  176 ?   ?   ?   A . n 
B 2 73  GLY 73  177 ?   ?   ?   A . n 
B 2 74  GLY 74  178 ?   ?   ?   A . n 
B 2 75  SER 75  179 ?   ?   ?   A . n 
B 2 76  GLY 76  180 ?   ?   ?   A . n 
B 2 77  GLY 77  181 ?   ?   ?   A . n 
B 2 78  THR 78  182 ?   ?   ?   A . n 
B 2 79  THR 79  183 183 THR THR A . n 
B 2 80  GLY 80  184 184 GLY GLY A . n 
B 2 81  ILE 81  185 185 ILE ILE A . n 
B 2 82  VAL 82  186 186 VAL VAL A . n 
B 2 83  GLU 83  187 187 GLU GLU A . n 
B 2 84  THR 84  188 188 THR THR A . n 
B 2 85  HIS 85  189 189 HIS HIS A . n 
B 2 86  PHE 86  190 190 PHE PHE A . n 
B 2 87  THR 87  191 191 THR THR A . n 
B 2 88  PHE 88  192 192 PHE PHE A . n 
B 2 89  LYS 89  193 193 LYS LYS A . n 
B 2 90  ASN 90  194 194 ASN ASN A . n 
B 2 91  LEU 91  195 195 LEU LEU A . n 
B 2 92  HIS 92  196 196 HIS HIS A . n 
B 2 93  PHE 93  197 197 PHE PHE A . n 
B 2 94  ARG 94  198 198 ARG ARG A . n 
B 2 95  LEU 95  199 199 LEU LEU A . n 
B 2 96  PHE 96  200 200 PHE PHE A . n 
B 2 97  ASP 97  201 201 ASP ASP A . n 
B 2 98  VAL 98  202 202 VAL VAL A . n 
B 2 99  GLY 99  203 203 GLY GLY A . n 
B 2 100 GLY 100 204 204 GLY GLY A . n 
B 2 101 GLN 101 205 205 GLN GLN A . n 
B 2 102 ARG 102 206 206 ARG ARG A . n 
B 2 103 SER 103 207 207 SER SER A . n 
B 2 104 GLU 104 208 208 GLU GLU A . n 
B 2 105 ARG 105 209 209 ARG ARG A . n 
B 2 106 LYS 106 210 210 LYS LYS A . n 
B 2 107 LYS 107 211 211 LYS LYS A . n 
B 2 108 TRP 108 212 212 TRP TRP A . n 
B 2 109 ILE 109 213 213 ILE ILE A . n 
B 2 110 HIS 110 214 214 HIS HIS A . n 
B 2 111 CYS 111 215 215 CYS CYS A . n 
B 2 112 PHE 112 216 216 PHE PHE A . n 
B 2 113 GLU 113 217 217 GLU GLU A . n 
B 2 114 ASP 114 218 218 ASP ASP A . n 
B 2 115 VAL 115 219 219 VAL VAL A . n 
B 2 116 THR 116 220 220 THR THR A . n 
B 2 117 ALA 117 221 221 ALA ALA A . n 
B 2 118 ILE 118 222 222 ILE ILE A . n 
B 2 119 ILE 119 223 223 ILE ILE A . n 
B 2 120 PHE 120 224 224 PHE PHE A . n 
B 2 121 CYS 121 225 225 CYS CYS A . n 
B 2 122 VAL 122 226 226 VAL VAL A . n 
B 2 123 ASP 123 227 227 ASP ASP A . n 
B 2 124 LEU 124 228 228 LEU LEU A . n 
B 2 125 SER 125 229 229 SER SER A . n 
B 2 126 ASP 126 240 ?   ?   ?   A . n 
B 2 127 TYR 127 241 ?   ?   ?   A . n 
B 2 128 ASN 128 242 ?   ?   ?   A . n 
B 2 129 ARG 129 243 ?   ?   ?   A . n 
B 2 130 MET 130 244 ?   ?   ?   A . n 
B 2 131 HIS 131 245 245 HIS HIS A . n 
B 2 132 GLU 132 246 246 GLU GLU A . n 
B 2 133 SER 133 247 247 SER SER A . n 
B 2 134 LEU 134 248 248 LEU LEU A . n 
B 2 135 MET 135 249 249 MET MET A . n 
B 2 136 LEU 136 250 250 LEU LEU A . n 
B 2 137 PHE 137 251 251 PHE PHE A . n 
B 2 138 ASP 138 252 252 ASP ASP A . n 
B 2 139 SER 139 253 253 SER SER A . n 
B 2 140 ILE 140 254 254 ILE ILE A . n 
B 2 141 CYS 141 255 255 CYS CYS A . n 
B 2 142 ASN 142 256 256 ASN ASN A . n 
B 2 143 ASN 143 257 257 ASN ASN A . n 
B 2 144 LYS 144 258 258 LYS LYS A . n 
B 2 145 PHE 145 259 259 PHE PHE A . n 
B 2 146 PHE 146 260 260 PHE PHE A . n 
B 2 147 ILE 147 261 261 ILE ILE A . n 
B 2 148 ASP 148 262 262 ASP ASP A . n 
B 2 149 THR 149 263 263 THR THR A . n 
B 2 150 SER 150 264 264 SER SER A . n 
B 2 151 ILE 151 265 265 ILE ILE A . n 
B 2 152 ILE 152 266 266 ILE ILE A . n 
B 2 153 LEU 153 267 267 LEU LEU A . n 
B 2 154 PHE 154 268 268 PHE PHE A . n 
B 2 155 LEU 155 269 269 LEU LEU A . n 
B 2 156 ASN 156 270 270 ASN ASN A . n 
B 2 157 LYS 157 271 271 LYS LYS A . n 
B 2 158 LYS 158 272 272 LYS LYS A . n 
B 2 159 ASP 159 273 273 ASP ASP A . n 
B 2 160 LEU 160 274 274 LEU LEU A . n 
B 2 161 PHE 161 275 275 PHE PHE A . n 
B 2 162 GLY 162 276 276 GLY GLY A . n 
B 2 163 GLU 163 277 277 GLU GLU A . n 
B 2 164 LYS 164 278 278 LYS LYS A . n 
B 2 165 ILE 165 279 279 ILE ILE A . n 
B 2 166 LYS 166 280 280 LYS LYS A . n 
B 2 167 LYS 167 281 281 LYS LYS A . n 
B 2 168 SER 168 282 282 SER SER A . n 
B 2 169 PRO 169 283 283 PRO PRO A . n 
B 2 170 LEU 170 284 284 LEU LEU A . n 
B 2 171 THR 171 285 285 THR THR A . n 
B 2 172 ILE 172 286 286 ILE ILE A . n 
B 2 173 CYS 173 287 287 CYS CYS A . n 
B 2 174 PHE 174 288 288 PHE PHE A . n 
B 2 175 PRO 175 289 289 PRO PRO A . n 
B 2 176 GLU 176 290 290 GLU GLU A . n 
B 2 177 TYR 177 291 291 TYR TYR A . n 
B 2 178 THR 178 292 292 THR THR A . n 
B 2 179 GLY 179 293 293 GLY GLY A . n 
B 2 180 PRO 180 294 294 PRO PRO A . n 
B 2 181 ASN 181 295 295 ASN ASN A . n 
B 2 182 THR 182 296 296 THR THR A . n 
B 2 183 TYR 183 297 297 TYR TYR A . n 
B 2 184 GLU 184 298 298 GLU GLU A . n 
B 2 185 ASP 185 299 299 ASP ASP A . n 
B 2 186 ALA 186 300 300 ALA ALA A . n 
B 2 187 ALA 187 301 301 ALA ALA A . n 
B 2 188 ALA 188 302 302 ALA ALA A . n 
B 2 189 TYR 189 303 303 TYR TYR A . n 
B 2 190 ILE 190 304 304 ILE ILE A . n 
B 2 191 GLN 191 305 305 GLN GLN A . n 
B 2 192 ALA 192 306 306 ALA ALA A . n 
B 2 193 GLN 193 307 307 GLN GLN A . n 
B 2 194 PHE 194 308 308 PHE PHE A . n 
B 2 195 GLU 195 309 309 GLU GLU A . n 
B 2 196 SER 196 310 310 SER SER A . n 
B 2 197 LYS 197 311 311 LYS LYS A . n 
B 2 198 ASN 198 312 312 ASN ASN A . n 
B 2 199 ARG 199 313 313 ARG ARG A . n 
B 2 200 SER 200 314 314 SER SER A . n 
B 2 201 PRO 201 315 315 PRO PRO A . n 
B 2 202 ASN 202 316 316 ASN ASN A . n 
B 2 203 LYS 203 317 317 LYS LYS A . n 
B 2 204 GLU 204 318 318 GLU GLU A . n 
B 2 205 ILE 205 319 319 ILE ILE A . n 
B 2 206 TYR 206 320 320 TYR TYR A . n 
B 2 207 CYS 207 321 321 CYS CYS A . n 
B 2 208 HIS 208 322 322 HIS HIS A . n 
B 2 209 MET 209 323 323 MET MET A . n 
B 2 210 THR 210 324 324 THR THR A . n 
B 2 211 CYS 211 325 325 CYS CYS A . n 
B 2 212 ALA 212 326 326 ALA ALA A . n 
B 2 213 THR 213 327 327 THR THR A . n 
B 2 214 ASP 214 328 328 ASP ASP A . n 
B 2 215 THR 215 329 329 THR THR A . n 
B 2 216 ASN 216 330 330 ASN ASN A . n 
B 2 217 ASN 217 331 331 ASN ASN A . n 
B 2 218 ALA 218 332 332 ALA ALA A . n 
B 2 219 GLN 219 333 333 GLN GLN A . n 
B 2 220 VAL 220 334 334 VAL VAL A . n 
B 2 221 ILE 221 335 335 ILE ILE A . n 
B 2 222 PHE 222 336 336 PHE PHE A . n 
B 2 223 ASP 223 337 337 ASP ASP A . n 
B 2 224 ALA 224 338 338 ALA ALA A . n 
B 2 225 VAL 225 339 339 VAL VAL A . n 
B 2 226 THR 226 340 340 THR THR A . n 
B 2 227 ASP 227 341 341 ASP ASP A . n 
B 2 228 ILE 228 342 342 ILE ILE A . n 
B 2 229 ILE 229 343 343 ILE ILE A . n 
B 2 230 ILE 230 344 344 ILE ILE A . n 
B 2 231 ALA 231 345 345 ALA ALA A . n 
B 2 232 ASN 232 346 346 ASN ASN A . n 
B 2 233 ASN 233 347 347 ASN ASN A . n 
B 2 234 LEU 234 348 348 LEU LEU A . n 
B 2 235 ARG 235 349 349 ARG ARG A . n 
B 2 236 GLY 236 350 350 GLY GLY A . n 
B 2 237 CYS 237 351 351 CYS CYS A . n 
B 2 238 GLY 238 352 352 GLY GLY A . n 
B 2 239 LEU 239 353 353 LEU LEU A . n 
B 2 240 TYR 240 354 354 TYR TYR A . n 
C 3 1   MET 1   -9  ?   ?   ?   B . n 
C 3 2   HIS 2   -8  ?   ?   ?   B . n 
C 3 3   HIS 3   -7  ?   ?   ?   B . n 
C 3 4   HIS 4   -6  ?   ?   ?   B . n 
C 3 5   HIS 5   -5  ?   ?   ?   B . n 
C 3 6   HIS 6   -4  ?   ?   ?   B . n 
C 3 7   HIS 7   -3  ?   ?   ?   B . n 
C 3 8   GLY 8   -2  ?   ?   ?   B . n 
C 3 9   SER 9   -1  ?   ?   ?   B . n 
C 3 10  SER 10  0   ?   ?   ?   B . n 
C 3 11  GLY 11  1   ?   ?   ?   B . n 
C 3 12  SER 12  2   ?   ?   ?   B . n 
C 3 13  GLU 13  3   ?   ?   ?   B . n 
C 3 14  LEU 14  4   ?   ?   ?   B . n 
C 3 15  ASP 15  5   5   ASP ASP B . n 
C 3 16  GLN 16  6   6   GLN GLN B . n 
C 3 17  LEU 17  7   7   LEU LEU B . n 
C 3 18  ARG 18  8   8   ARG ARG B . n 
C 3 19  GLN 19  9   9   GLN GLN B . n 
C 3 20  GLU 20  10  10  GLU GLU B . n 
C 3 21  ALA 21  11  11  ALA ALA B . n 
C 3 22  GLU 22  12  12  GLU GLU B . n 
C 3 23  GLN 23  13  13  GLN GLN B . n 
C 3 24  LEU 24  14  14  LEU LEU B . n 
C 3 25  LYS 25  15  15  LYS LYS B . n 
C 3 26  ASN 26  16  16  ASN ASN B . n 
C 3 27  GLN 27  17  17  GLN GLN B . n 
C 3 28  ILE 28  18  18  ILE ILE B . n 
C 3 29  ARG 29  19  19  ARG ARG B . n 
C 3 30  ASP 30  20  20  ASP ASP B . n 
C 3 31  ALA 31  21  21  ALA ALA B . n 
C 3 32  ARG 32  22  22  ARG ARG B . n 
C 3 33  LYS 33  23  23  LYS LYS B . n 
C 3 34  ALA 34  24  24  ALA ALA B . n 
C 3 35  CYS 35  25  25  CYS CYS B . n 
C 3 36  ALA 36  26  26  ALA ALA B . n 
C 3 37  ASP 37  27  27  ASP ASP B . n 
C 3 38  ALA 38  28  28  ALA ALA B . n 
C 3 39  THR 39  29  29  THR THR B . n 
C 3 40  LEU 40  30  30  LEU LEU B . n 
C 3 41  SER 41  31  31  SER SER B . n 
C 3 42  GLN 42  32  32  GLN GLN B . n 
C 3 43  ILE 43  33  33  ILE ILE B . n 
C 3 44  THR 44  34  34  THR THR B . n 
C 3 45  ASN 45  35  35  ASN ASN B . n 
C 3 46  ASN 46  36  36  ASN ASN B . n 
C 3 47  ILE 47  37  37  ILE ILE B . n 
C 3 48  ASP 48  38  38  ASP ASP B . n 
C 3 49  PRO 49  39  39  PRO PRO B . n 
C 3 50  VAL 50  40  40  VAL VAL B . n 
C 3 51  GLY 51  41  41  GLY GLY B . n 
C 3 52  ARG 52  42  42  ARG ARG B . n 
C 3 53  ILE 53  43  43  ILE ILE B . n 
C 3 54  GLN 54  44  44  GLN GLN B . n 
C 3 55  MET 55  45  45  MET MET B . n 
C 3 56  ARG 56  46  46  ARG ARG B . n 
C 3 57  THR 57  47  47  THR THR B . n 
C 3 58  ARG 58  48  48  ARG ARG B . n 
C 3 59  ARG 59  49  49  ARG ARG B . n 
C 3 60  THR 60  50  50  THR THR B . n 
C 3 61  LEU 61  51  51  LEU LEU B . n 
C 3 62  ARG 62  52  52  ARG ARG B . n 
C 3 63  GLY 63  53  53  GLY GLY B . n 
C 3 64  HIS 64  54  54  HIS HIS B . n 
C 3 65  LEU 65  55  55  LEU LEU B . n 
C 3 66  ALA 66  56  56  ALA ALA B . n 
C 3 67  LYS 67  57  57  LYS LYS B . n 
C 3 68  ILE 68  58  58  ILE ILE B . n 
C 3 69  TYR 69  59  59  TYR TYR B . n 
C 3 70  ALA 70  60  60  ALA ALA B . n 
C 3 71  MET 71  61  61  MET MET B . n 
C 3 72  HIS 72  62  62  HIS HIS B . n 
C 3 73  TRP 73  63  63  TRP TRP B . n 
C 3 74  GLY 74  64  64  GLY GLY B . n 
C 3 75  THR 75  65  65  THR THR B . n 
C 3 76  ASP 76  66  66  ASP ASP B . n 
C 3 77  SER 77  67  67  SER SER B . n 
C 3 78  ARG 78  68  68  ARG ARG B . n 
C 3 79  LEU 79  69  69  LEU LEU B . n 
C 3 80  LEU 80  70  70  LEU LEU B . n 
C 3 81  VAL 81  71  71  VAL VAL B . n 
C 3 82  SER 82  72  72  SER SER B . n 
C 3 83  ALA 83  73  73  ALA ALA B . n 
C 3 84  SER 84  74  74  SER SER B . n 
C 3 85  GLN 85  75  75  GLN GLN B . n 
C 3 86  ASP 86  76  76  ASP ASP B . n 
C 3 87  GLY 87  77  77  GLY GLY B . n 
C 3 88  LYS 88  78  78  LYS LYS B . n 
C 3 89  LEU 89  79  79  LEU LEU B . n 
C 3 90  ILE 90  80  80  ILE ILE B . n 
C 3 91  ILE 91  81  81  ILE ILE B . n 
C 3 92  TRP 92  82  82  TRP TRP B . n 
C 3 93  ASP 93  83  83  ASP ASP B . n 
C 3 94  SER 94  84  84  SER SER B . n 
C 3 95  TYR 95  85  85  TYR TYR B . n 
C 3 96  THR 96  86  86  THR THR B . n 
C 3 97  THR 97  87  87  THR THR B . n 
C 3 98  ASN 98  88  88  ASN ASN B . n 
C 3 99  LYS 99  89  89  LYS LYS B . n 
C 3 100 VAL 100 90  90  VAL VAL B . n 
C 3 101 HIS 101 91  91  HIS HIS B . n 
C 3 102 ALA 102 92  92  ALA ALA B . n 
C 3 103 ILE 103 93  93  ILE ILE B . n 
C 3 104 PRO 104 94  94  PRO PRO B . n 
C 3 105 LEU 105 95  95  LEU LEU B . n 
C 3 106 ARG 106 96  96  ARG ARG B . n 
C 3 107 SER 107 97  97  SER SER B . n 
C 3 108 SER 108 98  98  SER SER B . n 
C 3 109 TRP 109 99  99  TRP TRP B . n 
C 3 110 VAL 110 100 100 VAL VAL B . n 
C 3 111 MET 111 101 101 MET MET B . n 
C 3 112 THR 112 102 102 THR THR B . n 
C 3 113 CYS 113 103 103 CYS CYS B . n 
C 3 114 ALA 114 104 104 ALA ALA B . n 
C 3 115 TYR 115 105 105 TYR TYR B . n 
C 3 116 ALA 116 106 106 ALA ALA B . n 
C 3 117 PRO 117 107 107 PRO PRO B . n 
C 3 118 SER 118 108 108 SER SER B . n 
C 3 119 GLY 119 109 109 GLY GLY B . n 
C 3 120 ASN 120 110 110 ASN ASN B . n 
C 3 121 TYR 121 111 111 TYR TYR B . n 
C 3 122 VAL 122 112 112 VAL VAL B . n 
C 3 123 ALA 123 113 113 ALA ALA B . n 
C 3 124 CYS 124 114 114 CYS CYS B . n 
C 3 125 GLY 125 115 115 GLY GLY B . n 
C 3 126 GLY 126 116 116 GLY GLY B . n 
C 3 127 LEU 127 117 117 LEU LEU B . n 
C 3 128 ASP 128 118 118 ASP ASP B . n 
C 3 129 ASN 129 119 119 ASN ASN B . n 
C 3 130 ILE 130 120 120 ILE ILE B . n 
C 3 131 CYS 131 121 121 CYS CYS B . n 
C 3 132 SER 132 122 122 SER SER B . n 
C 3 133 ILE 133 123 123 ILE ILE B . n 
C 3 134 TYR 134 124 124 TYR TYR B . n 
C 3 135 ASN 135 125 125 ASN ASN B . n 
C 3 136 LEU 136 126 126 LEU LEU B . n 
C 3 137 LYS 137 127 127 LYS LYS B . n 
C 3 138 THR 138 128 128 THR THR B . n 
C 3 139 ARG 139 129 129 ARG ARG B . n 
C 3 140 GLU 140 130 130 GLU GLU B . n 
C 3 141 GLY 141 131 131 GLY GLY B . n 
C 3 142 ASN 142 132 132 ASN ASN B . n 
C 3 143 VAL 143 133 133 VAL VAL B . n 
C 3 144 ARG 144 134 134 ARG ARG B . n 
C 3 145 VAL 145 135 135 VAL VAL B . n 
C 3 146 SER 146 136 136 SER SER B . n 
C 3 147 ARG 147 137 137 ARG ARG B . n 
C 3 148 GLU 148 138 138 GLU GLU B . n 
C 3 149 LEU 149 139 139 LEU LEU B . n 
C 3 150 ALA 150 140 140 ALA ALA B . n 
C 3 151 GLY 151 141 141 GLY GLY B . n 
C 3 152 HIS 152 142 142 HIS HIS B . n 
C 3 153 THR 153 143 143 THR THR B . n 
C 3 154 GLY 154 144 144 GLY GLY B . n 
C 3 155 TYR 155 145 145 TYR TYR B . n 
C 3 156 LEU 156 146 146 LEU LEU B . n 
C 3 157 SER 157 147 147 SER SER B . n 
C 3 158 CYS 158 148 148 CYS CYS B . n 
C 3 159 CYS 159 149 149 CYS CYS B . n 
C 3 160 ARG 160 150 150 ARG ARG B . n 
C 3 161 PHE 161 151 151 PHE PHE B . n 
C 3 162 LEU 162 152 152 LEU LEU B . n 
C 3 163 ASP 163 153 153 ASP ASP B . n 
C 3 164 ASP 164 154 154 ASP ASP B . n 
C 3 165 ASN 165 155 155 ASN ASN B . n 
C 3 166 GLN 166 156 156 GLN GLN B . n 
C 3 167 ILE 167 157 157 ILE ILE B . n 
C 3 168 VAL 168 158 158 VAL VAL B . n 
C 3 169 THR 169 159 159 THR THR B . n 
C 3 170 SER 170 160 160 SER SER B . n 
C 3 171 SER 171 161 161 SER SER B . n 
C 3 172 GLY 172 162 162 GLY GLY B . n 
C 3 173 ASP 173 163 163 ASP ASP B . n 
C 3 174 THR 174 164 164 THR THR B . n 
C 3 175 THR 175 165 165 THR THR B . n 
C 3 176 CYS 176 166 166 CYS CYS B . n 
C 3 177 ALA 177 167 167 ALA ALA B . n 
C 3 178 LEU 178 168 168 LEU LEU B . n 
C 3 179 TRP 179 169 169 TRP TRP B . n 
C 3 180 ASP 180 170 170 ASP ASP B . n 
C 3 181 ILE 181 171 171 ILE ILE B . n 
C 3 182 GLU 182 172 172 GLU GLU B . n 
C 3 183 THR 183 173 173 THR THR B . n 
C 3 184 GLY 184 174 174 GLY GLY B . n 
C 3 185 GLN 185 175 175 GLN GLN B . n 
C 3 186 GLN 186 176 176 GLN GLN B . n 
C 3 187 THR 187 177 177 THR THR B . n 
C 3 188 THR 188 178 178 THR THR B . n 
C 3 189 THR 189 179 179 THR THR B . n 
C 3 190 PHE 190 180 180 PHE PHE B . n 
C 3 191 THR 191 181 181 THR THR B . n 
C 3 192 GLY 192 182 182 GLY GLY B . n 
C 3 193 HIS 193 183 183 HIS HIS B . n 
C 3 194 THR 194 184 184 THR THR B . n 
C 3 195 GLY 195 185 185 GLY GLY B . n 
C 3 196 ASP 196 186 186 ASP ASP B . n 
C 3 197 VAL 197 187 187 VAL VAL B . n 
C 3 198 MET 198 188 188 MET MET B . n 
C 3 199 SER 199 189 189 SER SER B . n 
C 3 200 LEU 200 190 190 LEU LEU B . n 
C 3 201 SER 201 191 191 SER SER B . n 
C 3 202 LEU 202 192 192 LEU LEU B . n 
C 3 203 ALA 203 193 193 ALA ALA B . n 
C 3 204 PRO 204 194 194 PRO PRO B . n 
C 3 205 ASP 205 195 195 ASP ASP B . n 
C 3 206 THR 206 196 196 THR THR B . n 
C 3 207 ARG 207 197 197 ARG ARG B . n 
C 3 208 LEU 208 198 198 LEU LEU B . n 
C 3 209 PHE 209 199 199 PHE PHE B . n 
C 3 210 VAL 210 200 200 VAL VAL B . n 
C 3 211 SER 211 201 201 SER SER B . n 
C 3 212 GLY 212 202 202 GLY GLY B . n 
C 3 213 ALA 213 203 203 ALA ALA B . n 
C 3 214 CYS 214 204 204 CYS CYS B . n 
C 3 215 ASP 215 205 205 ASP ASP B . n 
C 3 216 ALA 216 206 206 ALA ALA B . n 
C 3 217 SER 217 207 207 SER SER B . n 
C 3 218 ALA 218 208 208 ALA ALA B . n 
C 3 219 LYS 219 209 209 LYS LYS B . n 
C 3 220 LEU 220 210 210 LEU LEU B . n 
C 3 221 TRP 221 211 211 TRP TRP B . n 
C 3 222 ASP 222 212 212 ASP ASP B . n 
C 3 223 VAL 223 213 213 VAL VAL B . n 
C 3 224 ARG 224 214 214 ARG ARG B . n 
C 3 225 GLU 225 215 215 GLU GLU B . n 
C 3 226 GLY 226 216 216 GLY GLY B . n 
C 3 227 MET 227 217 217 MET MET B . n 
C 3 228 CYS 228 218 218 CYS CYS B . n 
C 3 229 ARG 229 219 219 ARG ARG B . n 
C 3 230 GLN 230 220 220 GLN GLN B . n 
C 3 231 THR 231 221 221 THR THR B . n 
C 3 232 PHE 232 222 222 PHE PHE B . n 
C 3 233 THR 233 223 223 THR THR B . n 
C 3 234 GLY 234 224 224 GLY GLY B . n 
C 3 235 HIS 235 225 225 HIS HIS B . n 
C 3 236 GLU 236 226 226 GLU GLU B . n 
C 3 237 SER 237 227 227 SER SER B . n 
C 3 238 ASP 238 228 228 ASP ASP B . n 
C 3 239 ILE 239 229 229 ILE ILE B . n 
C 3 240 ASN 240 230 230 ASN ASN B . n 
C 3 241 ALA 241 231 231 ALA ALA B . n 
C 3 242 ILE 242 232 232 ILE ILE B . n 
C 3 243 CYS 243 233 233 CYS CYS B . n 
C 3 244 PHE 244 234 234 PHE PHE B . n 
C 3 245 PHE 245 235 235 PHE PHE B . n 
C 3 246 PRO 246 236 236 PRO PRO B . n 
C 3 247 ASN 247 237 237 ASN ASN B . n 
C 3 248 GLY 248 238 238 GLY GLY B . n 
C 3 249 ASN 249 239 239 ASN ASN B . n 
C 3 250 ALA 250 240 240 ALA ALA B . n 
C 3 251 PHE 251 241 241 PHE PHE B . n 
C 3 252 ALA 252 242 242 ALA ALA B . n 
C 3 253 THR 253 243 243 THR THR B . n 
C 3 254 GLY 254 244 244 GLY GLY B . n 
C 3 255 SER 255 245 245 SER SER B . n 
C 3 256 ASP 256 246 246 ASP ASP B . n 
C 3 257 ASP 257 247 247 ASP ASP B . n 
C 3 258 ALA 258 248 248 ALA ALA B . n 
C 3 259 THR 259 249 249 THR THR B . n 
C 3 260 CYS 260 250 250 CYS CYS B . n 
C 3 261 ARG 261 251 251 ARG ARG B . n 
C 3 262 LEU 262 252 252 LEU LEU B . n 
C 3 263 PHE 263 253 253 PHE PHE B . n 
C 3 264 ASP 264 254 254 ASP ASP B . n 
C 3 265 LEU 265 255 255 LEU LEU B . n 
C 3 266 ARG 266 256 256 ARG ARG B . n 
C 3 267 ALA 267 257 257 ALA ALA B . n 
C 3 268 ASP 268 258 258 ASP ASP B . n 
C 3 269 GLN 269 259 259 GLN GLN B . n 
C 3 270 GLU 270 260 260 GLU GLU B . n 
C 3 271 LEU 271 261 261 LEU LEU B . n 
C 3 272 MET 272 262 262 MET MET B . n 
C 3 273 THR 273 263 263 THR THR B . n 
C 3 274 TYR 274 264 264 TYR TYR B . n 
C 3 275 SER 275 265 265 SER SER B . n 
C 3 276 HIS 276 266 266 HIS HIS B . n 
C 3 277 ASP 277 267 267 ASP ASP B . n 
C 3 278 ASN 278 268 268 ASN ASN B . n 
C 3 279 ILE 279 269 269 ILE ILE B . n 
C 3 280 ILE 280 270 270 ILE ILE B . n 
C 3 281 CYS 281 271 271 CYS CYS B . n 
C 3 282 GLY 282 272 272 GLY GLY B . n 
C 3 283 ILE 283 273 273 ILE ILE B . n 
C 3 284 THR 284 274 274 THR THR B . n 
C 3 285 SER 285 275 275 SER SER B . n 
C 3 286 VAL 286 276 276 VAL VAL B . n 
C 3 287 SER 287 277 277 SER SER B . n 
C 3 288 PHE 288 278 278 PHE PHE B . n 
C 3 289 SER 289 279 279 SER SER B . n 
C 3 290 LYS 290 280 280 LYS LYS B . n 
C 3 291 SER 291 281 281 SER SER B . n 
C 3 292 GLY 292 282 282 GLY GLY B . n 
C 3 293 ARG 293 283 283 ARG ARG B . n 
C 3 294 LEU 294 284 284 LEU LEU B . n 
C 3 295 LEU 295 285 285 LEU LEU B . n 
C 3 296 LEU 296 286 286 LEU LEU B . n 
C 3 297 ALA 297 287 287 ALA ALA B . n 
C 3 298 GLY 298 288 288 GLY GLY B . n 
C 3 299 TYR 299 289 289 TYR TYR B . n 
C 3 300 ASP 300 290 290 ASP ASP B . n 
C 3 301 ASP 301 291 291 ASP ASP B . n 
C 3 302 PHE 302 292 292 PHE PHE B . n 
C 3 303 ASN 303 293 293 ASN ASN B . n 
C 3 304 CYS 304 294 294 CYS CYS B . n 
C 3 305 ASN 305 295 295 ASN ASN B . n 
C 3 306 VAL 306 296 296 VAL VAL B . n 
C 3 307 TRP 307 297 297 TRP TRP B . n 
C 3 308 ASP 308 298 298 ASP ASP B . n 
C 3 309 ALA 309 299 299 ALA ALA B . n 
C 3 310 LEU 310 300 300 LEU LEU B . n 
C 3 311 LYS 311 301 301 LYS LYS B . n 
C 3 312 ALA 312 302 302 ALA ALA B . n 
C 3 313 ASP 313 303 303 ASP ASP B . n 
C 3 314 ARG 314 304 304 ARG ARG B . n 
C 3 315 ALA 315 305 305 ALA ALA B . n 
C 3 316 GLY 316 306 306 GLY GLY B . n 
C 3 317 VAL 317 307 307 VAL VAL B . n 
C 3 318 LEU 318 308 308 LEU LEU B . n 
C 3 319 ALA 319 309 309 ALA ALA B . n 
C 3 320 GLY 320 310 310 GLY GLY B . n 
C 3 321 HIS 321 311 311 HIS HIS B . n 
C 3 322 ASP 322 312 312 ASP ASP B . n 
C 3 323 ASN 323 313 313 ASN ASN B . n 
C 3 324 ARG 324 314 314 ARG ARG B . n 
C 3 325 VAL 325 315 315 VAL VAL B . n 
C 3 326 SER 326 316 316 SER SER B . n 
C 3 327 CYS 327 317 317 CYS CYS B . n 
C 3 328 LEU 328 318 318 LEU LEU B . n 
C 3 329 GLY 329 319 319 GLY GLY B . n 
C 3 330 VAL 330 320 320 VAL VAL B . n 
C 3 331 THR 331 321 321 THR THR B . n 
C 3 332 ASP 332 322 322 ASP ASP B . n 
C 3 333 ASP 333 323 323 ASP ASP B . n 
C 3 334 GLY 334 324 324 GLY GLY B . n 
C 3 335 MET 335 325 325 MET MET B . n 
C 3 336 ALA 336 326 326 ALA ALA B . n 
C 3 337 VAL 337 327 327 VAL VAL B . n 
C 3 338 ALA 338 328 328 ALA ALA B . n 
C 3 339 THR 339 329 329 THR THR B . n 
C 3 340 GLY 340 330 330 GLY GLY B . n 
C 3 341 SER 341 331 331 SER SER B . n 
C 3 342 TRP 342 332 332 TRP TRP B . n 
C 3 343 ASP 343 333 333 ASP ASP B . n 
C 3 344 SER 344 334 334 SER SER B . n 
C 3 345 PHE 345 335 335 PHE PHE B . n 
C 3 346 LEU 346 336 336 LEU LEU B . n 
C 3 347 LYS 347 337 337 LYS LYS B . n 
C 3 348 ILE 348 338 338 ILE ILE B . n 
C 3 349 TRP 349 339 339 TRP TRP B . n 
C 3 350 ASN 350 340 340 ASN ASN B . n 
D 4 1   MET 1   1   ?   ?   ?   G . n 
D 4 2   ALA 2   2   ?   ?   ?   G . n 
D 4 3   SER 3   3   ?   ?   ?   G . n 
D 4 4   ASN 4   4   ?   ?   ?   G . n 
D 4 5   ASN 5   5   ?   ?   ?   G . n 
D 4 6   THR 6   6   ?   ?   ?   G . n 
D 4 7   ALA 7   7   ?   ?   ?   G . n 
D 4 8   SER 8   8   ?   ?   ?   G . n 
D 4 9   ILE 9   9   9   ILE ILE G . n 
D 4 10  ALA 10  10  10  ALA ALA G . n 
D 4 11  GLN 11  11  11  GLN GLN G . n 
D 4 12  ALA 12  12  12  ALA ALA G . n 
D 4 13  ARG 13  13  13  ARG ARG G . n 
D 4 14  LYS 14  14  14  LYS LYS G . n 
D 4 15  LEU 15  15  15  LEU LEU G . n 
D 4 16  VAL 16  16  16  VAL VAL G . n 
D 4 17  GLU 17  17  17  GLU GLU G . n 
D 4 18  GLN 18  18  18  GLN GLN G . n 
D 4 19  LEU 19  19  19  LEU LEU G . n 
D 4 20  LYS 20  20  20  LYS LYS G . n 
D 4 21  MET 21  21  21  MET MET G . n 
D 4 22  GLU 22  22  22  GLU GLU G . n 
D 4 23  ALA 23  23  23  ALA ALA G . n 
D 4 24  ASN 24  24  24  ASN ASN G . n 
D 4 25  ILE 25  25  25  ILE ILE G . n 
D 4 26  ASP 26  26  26  ASP ASP G . n 
D 4 27  ARG 27  27  27  ARG ARG G . n 
D 4 28  ILE 28  28  28  ILE ILE G . n 
D 4 29  LYS 29  29  29  LYS LYS G . n 
D 4 30  VAL 30  30  30  VAL VAL G . n 
D 4 31  SER 31  31  31  SER SER G . n 
D 4 32  LYS 32  32  32  LYS LYS G . n 
D 4 33  ALA 33  33  33  ALA ALA G . n 
D 4 34  ALA 34  34  34  ALA ALA G . n 
D 4 35  ALA 35  35  35  ALA ALA G . n 
D 4 36  ASP 36  36  36  ASP ASP G . n 
D 4 37  LEU 37  37  37  LEU LEU G . n 
D 4 38  MET 38  38  38  MET MET G . n 
D 4 39  ALA 39  39  39  ALA ALA G . n 
D 4 40  TYR 40  40  40  TYR TYR G . n 
D 4 41  CYS 41  41  41  CYS CYS G . n 
D 4 42  GLU 42  42  42  GLU GLU G . n 
D 4 43  ALA 43  43  43  ALA ALA G . n 
D 4 44  HIS 44  44  44  HIS HIS G . n 
D 4 45  ALA 45  45  45  ALA ALA G . n 
D 4 46  LYS 46  46  46  LYS LYS G . n 
D 4 47  GLU 47  47  47  GLU GLU G . n 
D 4 48  ASP 48  48  48  ASP ASP G . n 
D 4 49  PRO 49  49  49  PRO PRO G . n 
D 4 50  LEU 50  50  50  LEU LEU G . n 
D 4 51  LEU 51  51  51  LEU LEU G . n 
D 4 52  THR 52  52  52  THR THR G . n 
D 4 53  PRO 53  53  53  PRO PRO G . n 
D 4 54  VAL 54  54  54  VAL VAL G . n 
D 4 55  PRO 55  55  55  PRO PRO G . n 
D 4 56  ALA 56  56  56  ALA ALA G . n 
D 4 57  SER 57  57  57  SER SER G . n 
D 4 58  GLU 58  58  58  GLU GLU G . n 
D 4 59  ASN 59  59  59  ASN ASN G . n 
D 4 60  PRO 60  60  60  PRO PRO G . n 
D 4 61  PHE 61  61  61  PHE PHE G . n 
D 4 62  ARG 62  62  ?   ?   ?   G . n 
D 4 63  GLU 63  63  ?   ?   ?   G . n 
D 4 64  LYS 64  64  ?   ?   ?   G . n 
D 4 65  LYS 65  65  ?   ?   ?   G . n 
D 4 66  PHE 66  66  ?   ?   ?   G . n 
D 4 67  PHE 67  67  ?   ?   ?   G . n 
D 4 68  CYS 68  68  ?   ?   ?   G . n 
D 4 69  ALA 69  69  ?   ?   ?   G . n 
D 4 70  ILE 70  70  ?   ?   ?   G . n 
D 4 71  LEU 71  71  ?   ?   ?   G . n 
E 5 1   ASP 1   1   1   ASP ASP S . n 
E 5 2   VAL 2   2   2   VAL VAL S . n 
E 5 3   GLN 3   3   3   GLN GLN S . n 
E 5 4   LEU 4   4   4   LEU LEU S . n 
E 5 5   VAL 5   5   5   VAL VAL S . n 
E 5 6   GLU 6   6   6   GLU GLU S . n 
E 5 7   SER 7   7   7   SER SER S . n 
E 5 8   GLY 8   8   8   GLY GLY S . n 
E 5 9   GLY 9   9   9   GLY GLY S . n 
E 5 10  GLY 10  10  10  GLY GLY S . n 
E 5 11  LEU 11  11  11  LEU LEU S . n 
E 5 12  VAL 12  12  12  VAL VAL S . n 
E 5 13  GLN 13  13  13  GLN GLN S . n 
E 5 14  PRO 14  14  14  PRO PRO S . n 
E 5 15  GLY 15  15  15  GLY GLY S . n 
E 5 16  GLY 16  16  16  GLY GLY S . n 
E 5 17  SER 17  17  17  SER SER S . n 
E 5 18  ARG 18  18  18  ARG ARG S . n 
E 5 19  LYS 19  19  19  LYS LYS S . n 
E 5 20  LEU 20  20  20  LEU LEU S . n 
E 5 21  SER 21  21  21  SER SER S . n 
E 5 22  CYS 22  22  22  CYS CYS S . n 
E 5 23  SER 23  23  23  SER SER S . n 
E 5 24  ALA 24  24  24  ALA ALA S . n 
E 5 25  SER 25  25  25  SER SER S . n 
E 5 26  GLY 26  26  26  GLY GLY S . n 
E 5 27  PHE 27  27  27  PHE PHE S . n 
E 5 28  ALA 28  28  28  ALA ALA S . n 
E 5 29  PHE 29  29  29  PHE PHE S . n 
E 5 30  SER 30  30  30  SER SER S . n 
E 5 31  SER 31  31  31  SER SER S . n 
E 5 32  PHE 32  32  32  PHE PHE S . n 
E 5 33  GLY 33  33  33  GLY GLY S . n 
E 5 34  MET 34  34  34  MET MET S . n 
E 5 35  HIS 35  35  35  HIS HIS S . n 
E 5 36  TRP 36  36  36  TRP TRP S . n 
E 5 37  VAL 37  37  37  VAL VAL S . n 
E 5 38  ARG 38  38  38  ARG ARG S . n 
E 5 39  GLN 39  39  39  GLN GLN S . n 
E 5 40  ALA 40  40  40  ALA ALA S . n 
E 5 41  PRO 41  41  41  PRO PRO S . n 
E 5 42  GLU 42  42  42  GLU GLU S . n 
E 5 43  LYS 43  43  43  LYS LYS S . n 
E 5 44  GLY 44  44  44  GLY GLY S . n 
E 5 45  LEU 45  45  45  LEU LEU S . n 
E 5 46  GLU 46  46  46  GLU GLU S . n 
E 5 47  TRP 47  47  47  TRP TRP S . n 
E 5 48  VAL 48  48  48  VAL VAL S . n 
E 5 49  ALA 49  49  49  ALA ALA S . n 
E 5 50  TYR 50  50  50  TYR TYR S . n 
E 5 51  ILE 51  51  51  ILE ILE S . n 
E 5 52  SER 52  52  52  SER SER S . n 
E 5 53  SER 53  53  53  SER SER S . n 
E 5 54  GLY 54  54  54  GLY GLY S . n 
E 5 55  SER 55  55  55  SER SER S . n 
E 5 56  GLY 56  56  56  GLY GLY S . n 
E 5 57  THR 57  57  57  THR THR S . n 
E 5 58  ILE 58  58  58  ILE ILE S . n 
E 5 59  TYR 59  59  59  TYR TYR S . n 
E 5 60  TYR 60  60  60  TYR TYR S . n 
E 5 61  ALA 61  61  61  ALA ALA S . n 
E 5 62  ASP 62  62  62  ASP ASP S . n 
E 5 63  THR 63  63  63  THR THR S . n 
E 5 64  VAL 64  64  64  VAL VAL S . n 
E 5 65  LYS 65  65  65  LYS LYS S . n 
E 5 66  GLY 66  66  66  GLY GLY S . n 
E 5 67  ARG 67  67  67  ARG ARG S . n 
E 5 68  PHE 68  68  68  PHE PHE S . n 
E 5 69  THR 69  69  69  THR THR S . n 
E 5 70  ILE 70  70  70  ILE ILE S . n 
E 5 71  SER 71  71  71  SER SER S . n 
E 5 72  ARG 72  72  72  ARG ARG S . n 
E 5 73  ASP 73  73  73  ASP ASP S . n 
E 5 74  ASP 74  74  74  ASP ASP S . n 
E 5 75  PRO 75  75  75  PRO PRO S . n 
E 5 76  LYS 76  76  76  LYS LYS S . n 
E 5 77  ASN 77  77  77  ASN ASN S . n 
E 5 78  THR 78  78  78  THR THR S . n 
E 5 79  LEU 79  79  79  LEU LEU S . n 
E 5 80  PHE 80  80  80  PHE PHE S . n 
E 5 81  LEU 81  81  81  LEU LEU S . n 
E 5 82  GLN 82  82  82  GLN GLN S . n 
E 5 83  MET 83  83  83  MET MET S . n 
E 5 84  THR 84  84  84  THR THR S . n 
E 5 85  SER 85  85  85  SER SER S . n 
E 5 86  LEU 86  86  86  LEU LEU S . n 
E 5 87  ARG 87  87  87  ARG ARG S . n 
E 5 88  SER 88  88  88  SER SER S . n 
E 5 89  GLU 89  89  89  GLU GLU S . n 
E 5 90  ASP 90  90  90  ASP ASP S . n 
E 5 91  THR 91  91  91  THR THR S . n 
E 5 92  ALA 92  92  92  ALA ALA S . n 
E 5 93  MET 93  93  93  MET MET S . n 
E 5 94  TYR 94  94  94  TYR TYR S . n 
E 5 95  TYR 95  95  95  TYR TYR S . n 
E 5 96  CYS 96  96  96  CYS CYS S . n 
E 5 97  VAL 97  97  97  VAL VAL S . n 
E 5 98  ARG 98  98  98  ARG ARG S . n 
E 5 99  SER 99  99  99  SER SER S . n 
E 5 100 ILE 100 100 100 ILE ILE S . n 
E 5 101 TYR 101 101 101 TYR TYR S . n 
E 5 102 TYR 102 102 102 TYR TYR S . n 
E 5 103 TYR 103 103 103 TYR TYR S . n 
E 5 104 GLY 104 104 104 GLY GLY S . n 
E 5 105 SER 105 105 105 SER SER S . n 
E 5 106 SER 106 106 106 SER SER S . n 
E 5 107 PRO 107 107 107 PRO PRO S . n 
E 5 108 PHE 108 108 108 PHE PHE S . n 
E 5 109 ASP 109 109 109 ASP ASP S . n 
E 5 110 PHE 110 110 110 PHE PHE S . n 
E 5 111 TRP 111 111 111 TRP TRP S . n 
E 5 112 GLY 112 112 112 GLY GLY S . n 
E 5 113 GLN 113 113 113 GLN GLN S . n 
E 5 114 GLY 114 114 114 GLY GLY S . n 
E 5 115 THR 115 115 115 THR THR S . n 
E 5 116 THR 116 116 116 THR THR S . n 
E 5 117 LEU 117 117 117 LEU LEU S . n 
E 5 118 THR 118 118 118 THR THR S . n 
E 5 119 VAL 119 119 119 VAL VAL S . n 
E 5 120 SER 120 120 120 SER SER S . n 
E 5 121 SER 121 121 121 SER SER S . n 
E 5 122 GLY 122 121 ?   ?   ?   S A n 
E 5 123 GLY 123 121 ?   ?   ?   S B n 
E 5 124 GLY 124 121 ?   ?   ?   S C n 
E 5 125 GLY 125 121 ?   ?   ?   S D n 
E 5 126 SER 126 121 ?   ?   ?   S E n 
E 5 127 GLY 127 121 ?   ?   ?   S F n 
E 5 128 GLY 128 121 ?   ?   ?   S G n 
E 5 129 GLY 129 121 ?   ?   ?   S H n 
E 5 130 GLY 130 121 ?   ?   ?   S I n 
E 5 131 SER 131 121 ?   ?   ?   S J n 
E 5 132 GLY 132 121 ?   ?   ?   S K n 
E 5 133 GLY 133 121 ?   ?   ?   S L n 
E 5 134 GLY 134 121 ?   ?   ?   S M n 
E 5 135 GLY 135 121 ?   ?   ?   S N n 
E 5 136 SER 136 124 124 SER SER S . n 
E 5 137 ASP 137 125 125 ASP ASP S . n 
E 5 138 ILE 138 126 126 ILE ILE S . n 
E 5 139 VAL 139 127 127 VAL VAL S . n 
E 5 140 MET 140 128 128 MET MET S . n 
E 5 141 THR 141 129 129 THR THR S . n 
E 5 142 GLN 142 130 130 GLN GLN S . n 
E 5 143 ALA 143 131 131 ALA ALA S . n 
E 5 144 THR 144 132 132 THR THR S . n 
E 5 145 SER 145 133 133 SER SER S . n 
E 5 146 SER 146 134 134 SER SER S . n 
E 5 147 VAL 147 135 135 VAL VAL S . n 
E 5 148 PRO 148 136 136 PRO PRO S . n 
E 5 149 VAL 149 137 137 VAL VAL S . n 
E 5 150 THR 150 138 138 THR THR S . n 
E 5 151 PRO 151 139 139 PRO PRO S . n 
E 5 152 GLY 152 140 140 GLY GLY S . n 
E 5 153 GLU 153 141 141 GLU GLU S . n 
E 5 154 SER 154 142 142 SER SER S . n 
E 5 155 VAL 155 143 143 VAL VAL S . n 
E 5 156 SER 156 144 144 SER SER S . n 
E 5 157 ILE 157 145 145 ILE ILE S . n 
E 5 158 SER 158 146 146 SER SER S . n 
E 5 159 CYS 159 147 147 CYS CYS S . n 
E 5 160 ARG 160 148 148 ARG ARG S . n 
E 5 161 SER 161 149 149 SER SER S . n 
E 5 162 SER 162 150 150 SER SER S . n 
E 5 163 LYS 163 151 151 LYS LYS S . n 
E 5 164 SER 164 152 152 SER SER S . n 
E 5 165 LEU 165 153 153 LEU LEU S . n 
E 5 166 LEU 166 154 154 LEU LEU S . n 
E 5 167 HIS 167 155 155 HIS HIS S . n 
E 5 168 SER 168 156 156 SER SER S . n 
E 5 169 ASN 169 157 157 ASN ASN S . n 
E 5 170 GLY 170 158 158 GLY GLY S . n 
E 5 171 ASN 171 159 159 ASN ASN S . n 
E 5 172 THR 172 160 160 THR THR S . n 
E 5 173 TYR 173 161 161 TYR TYR S . n 
E 5 174 LEU 174 162 162 LEU LEU S . n 
E 5 175 TYR 175 163 163 TYR TYR S . n 
E 5 176 TRP 176 164 164 TRP TRP S . n 
E 5 177 PHE 177 165 165 PHE PHE S . n 
E 5 178 LEU 178 166 166 LEU LEU S . n 
E 5 179 GLN 179 167 167 GLN GLN S . n 
E 5 180 ARG 180 168 168 ARG ARG S . n 
E 5 181 PRO 181 169 169 PRO PRO S . n 
E 5 182 GLY 182 170 170 GLY GLY S . n 
E 5 183 GLN 183 171 171 GLN GLN S . n 
E 5 184 SER 184 172 172 SER SER S . n 
E 5 185 PRO 185 173 173 PRO PRO S . n 
E 5 186 GLN 186 174 174 GLN GLN S . n 
E 5 187 LEU 187 175 175 LEU LEU S . n 
E 5 188 LEU 188 176 176 LEU LEU S . n 
E 5 189 ILE 189 177 177 ILE ILE S . n 
E 5 190 TYR 190 178 178 TYR TYR S . n 
E 5 191 ARG 191 179 179 ARG ARG S . n 
E 5 192 MET 192 180 180 MET MET S . n 
E 5 193 SER 193 181 181 SER SER S . n 
E 5 194 ASN 194 182 182 ASN ASN S . n 
E 5 195 LEU 195 183 183 LEU LEU S . n 
E 5 196 ALA 196 184 184 ALA ALA S . n 
E 5 197 SER 197 185 185 SER SER S . n 
E 5 198 GLY 198 186 186 GLY GLY S . n 
E 5 199 VAL 199 187 187 VAL VAL S . n 
E 5 200 PRO 200 188 188 PRO PRO S . n 
E 5 201 ASP 201 189 189 ASP ASP S . n 
E 5 202 ARG 202 190 190 ARG ARG S . n 
E 5 203 PHE 203 191 191 PHE PHE S . n 
E 5 204 SER 204 192 192 SER SER S . n 
E 5 205 GLY 205 193 193 GLY GLY S . n 
E 5 206 SER 206 194 194 SER SER S . n 
E 5 207 GLY 207 195 195 GLY GLY S . n 
E 5 208 SER 208 196 196 SER SER S . n 
E 5 209 GLY 209 197 197 GLY GLY S . n 
E 5 210 THR 210 198 198 THR THR S . n 
E 5 211 ALA 211 199 199 ALA ALA S . n 
E 5 212 PHE 212 200 200 PHE PHE S . n 
E 5 213 THR 213 201 201 THR THR S . n 
E 5 214 LEU 214 202 202 LEU LEU S . n 
E 5 215 THR 215 203 203 THR THR S . n 
E 5 216 ILE 216 204 204 ILE ILE S . n 
E 5 217 SER 217 205 205 SER SER S . n 
E 5 218 ARG 218 206 206 ARG ARG S . n 
E 5 219 LEU 219 207 207 LEU LEU S . n 
E 5 220 GLU 220 208 208 GLU GLU S . n 
E 5 221 ALA 221 209 209 ALA ALA S . n 
E 5 222 GLU 222 210 210 GLU GLU S . n 
E 5 223 ASP 223 211 211 ASP ASP S . n 
E 5 224 VAL 224 212 212 VAL VAL S . n 
E 5 225 GLY 225 213 213 GLY GLY S . n 
E 5 226 VAL 226 214 214 VAL VAL S . n 
E 5 227 TYR 227 215 215 TYR TYR S . n 
E 5 228 TYR 228 216 216 TYR TYR S . n 
E 5 229 CYS 229 217 217 CYS CYS S . n 
E 5 230 MET 230 218 218 MET MET S . n 
E 5 231 GLN 231 219 219 GLN GLN S . n 
E 5 232 HIS 232 220 220 HIS HIS S . n 
E 5 233 LEU 233 221 221 LEU LEU S . n 
E 5 234 GLU 234 222 222 GLU GLU S . n 
E 5 235 TYR 235 223 223 TYR TYR S . n 
E 5 236 PRO 236 224 224 PRO PRO S . n 
E 5 237 LEU 237 225 225 LEU LEU S . n 
E 5 238 THR 238 226 226 THR THR S . n 
E 5 239 PHE 239 227 227 PHE PHE S . n 
E 5 240 GLY 240 228 228 GLY GLY S . n 
E 5 241 ALA 241 229 229 ALA ALA S . n 
E 5 242 GLY 242 230 230 GLY GLY S . n 
E 5 243 THR 243 231 231 THR THR S . n 
E 5 244 LYS 244 232 232 LYS LYS S . n 
E 5 245 LEU 245 233 233 LEU LEU S . n 
E 5 246 GLU 246 234 234 GLU GLU S . n 
E 5 247 LEU 247 235 235 LEU LEU S . n 
E 5 248 LYS 248 236 ?   ?   ?   S . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 R GLU 40  ? CG  ? A GLU 96  CG  
2   1 Y 1 R GLU 40  ? CD  ? A GLU 96  CD  
3   1 Y 1 R GLU 40  ? OE1 ? A GLU 96  OE1 
4   1 Y 1 R GLU 40  ? OE2 ? A GLU 96  OE2 
5   1 Y 1 R GLU 42  ? CG  ? A GLU 98  CG  
6   1 Y 1 R GLU 42  ? CD  ? A GLU 98  CD  
7   1 Y 1 R GLU 42  ? OE1 ? A GLU 98  OE1 
8   1 Y 1 R GLU 42  ? OE2 ? A GLU 98  OE2 
9   1 Y 1 R GLU 45  ? CG  ? A GLU 101 CG  
10  1 Y 1 R GLU 45  ? CD  ? A GLU 101 CD  
11  1 Y 1 R GLU 45  ? OE1 ? A GLU 101 OE1 
12  1 Y 1 R GLU 45  ? OE2 ? A GLU 101 OE2 
13  1 Y 1 R ASN 47  ? CG  ? A ASN 103 CG  
14  1 Y 1 R ASN 47  ? OD1 ? A ASN 103 OD1 
15  1 Y 1 R ASN 47  ? ND2 ? A ASN 103 ND2 
16  1 Y 1 R LYS 48  ? CG  ? A LYS 104 CG  
17  1 Y 1 R LYS 48  ? CD  ? A LYS 104 CD  
18  1 Y 1 R LYS 48  ? CE  ? A LYS 104 CE  
19  1 Y 1 R LYS 48  ? NZ  ? A LYS 104 NZ  
20  1 Y 1 R TYR 49  ? CG  ? A TYR 105 CG  
21  1 Y 1 R TYR 49  ? CD1 ? A TYR 105 CD1 
22  1 Y 1 R TYR 49  ? CD2 ? A TYR 105 CD2 
23  1 Y 1 R TYR 49  ? CE1 ? A TYR 105 CE1 
24  1 Y 1 R TYR 49  ? CE2 ? A TYR 105 CE2 
25  1 Y 1 R TYR 49  ? CZ  ? A TYR 105 CZ  
26  1 Y 1 R TYR 49  ? OH  ? A TYR 105 OH  
27  1 Y 1 R LEU 57  ? CG  ? A LEU 113 CG  
28  1 Y 1 R LEU 57  ? CD1 ? A LEU 113 CD1 
29  1 Y 1 R LEU 57  ? CD2 ? A LEU 113 CD2 
30  1 Y 1 R LEU 60  ? CG  ? A LEU 116 CG  
31  1 Y 1 R LEU 60  ? CD1 ? A LEU 116 CD1 
32  1 Y 1 R LEU 60  ? CD2 ? A LEU 116 CD2 
33  1 Y 1 R LYS 158 ? CG  ? A LYS 214 CG  
34  1 Y 1 R LYS 158 ? CD  ? A LYS 214 CD  
35  1 Y 1 R LYS 158 ? CE  ? A LYS 214 CE  
36  1 Y 1 R LYS 158 ? NZ  ? A LYS 214 NZ  
37  1 Y 1 R LYS 163 ? CG  ? A LYS 219 CG  
38  1 Y 1 R LYS 163 ? CD  ? A LYS 219 CD  
39  1 Y 1 R LYS 163 ? CE  ? A LYS 219 CE  
40  1 Y 1 R LYS 163 ? NZ  ? A LYS 219 NZ  
41  1 Y 1 R LEU 167 ? CG  ? A LEU 223 CG  
42  1 Y 1 R LEU 167 ? CD1 ? A LEU 223 CD1 
43  1 Y 1 R LEU 167 ? CD2 ? A LEU 223 CD2 
44  1 Y 1 R LEU 174 ? CG  ? A LEU 230 CG  
45  1 Y 1 R LEU 174 ? CD1 ? A LEU 230 CD1 
46  1 Y 1 R LEU 174 ? CD2 ? A LEU 230 CD2 
47  1 Y 1 R MET 209 ? CG  ? A MET 265 CG  
48  1 Y 1 R MET 209 ? SD  ? A MET 265 SD  
49  1 Y 1 R MET 209 ? CE  ? A MET 265 CE  
50  1 Y 1 R LEU 228 ? CG  ? A LEU 284 CG  
51  1 Y 1 R LEU 228 ? CD1 ? A LEU 284 CD1 
52  1 Y 1 R LEU 228 ? CD2 ? A LEU 284 CD2 
53  1 Y 1 R LYS 240 ? CG  ? A LYS 296 CG  
54  1 Y 1 R LYS 240 ? CD  ? A LYS 296 CD  
55  1 Y 1 R LYS 240 ? CE  ? A LYS 296 CE  
56  1 Y 1 R LYS 240 ? NZ  ? A LYS 296 NZ  
57  1 Y 1 R LEU 272 ? CG  ? A LEU 328 CG  
58  1 Y 1 R LEU 272 ? CD1 ? A LEU 328 CD1 
59  1 Y 1 R LEU 272 ? CD2 ? A LEU 328 CD2 
60  1 Y 1 R GLN 280 ? CG  ? A GLN 336 CG  
61  1 Y 1 R GLN 280 ? CD  ? A GLN 336 CD  
62  1 Y 1 R GLN 280 ? OE1 ? A GLN 336 OE1 
63  1 Y 1 R GLN 280 ? NE2 ? A GLN 336 NE2 
64  1 Y 1 R GLU 287 ? CG  ? A GLU 343 CG  
65  1 Y 1 R GLU 287 ? CD  ? A GLU 343 CD  
66  1 Y 1 R GLU 287 ? OE1 ? A GLU 343 OE1 
67  1 Y 1 R GLU 287 ? OE2 ? A GLU 343 OE2 
68  1 Y 1 R LYS 320 ? CG  ? A LYS 376 CG  
69  1 Y 1 R LYS 320 ? CD  ? A LYS 376 CD  
70  1 Y 1 R LYS 320 ? CE  ? A LYS 376 CE  
71  1 Y 1 R LYS 320 ? NZ  ? A LYS 376 NZ  
72  1 Y 1 R LEU 326 ? CG  ? A LEU 382 CG  
73  1 Y 1 R LEU 326 ? CD1 ? A LEU 382 CD1 
74  1 Y 1 R LEU 326 ? CD2 ? A LEU 382 CD2 
75  1 Y 1 A GLU 246 ? CG  ? B GLU 132 CG  
76  1 Y 1 A GLU 246 ? CD  ? B GLU 132 CD  
77  1 Y 1 A GLU 246 ? OE1 ? B GLU 132 OE1 
78  1 Y 1 A GLU 246 ? OE2 ? B GLU 132 OE2 
79  1 Y 1 A LYS 278 ? CG  ? B LYS 164 CG  
80  1 Y 1 A LYS 278 ? CD  ? B LYS 164 CD  
81  1 Y 1 A LYS 278 ? CE  ? B LYS 164 CE  
82  1 Y 1 A LYS 278 ? NZ  ? B LYS 164 NZ  
83  1 Y 1 A LYS 281 ? CG  ? B LYS 167 CG  
84  1 Y 1 A LYS 281 ? CD  ? B LYS 167 CD  
85  1 Y 1 A LYS 281 ? CE  ? B LYS 167 CE  
86  1 Y 1 A LYS 281 ? NZ  ? B LYS 167 NZ  
87  1 Y 1 B ASP 5   ? CG  ? C ASP 15  CG  
88  1 Y 1 B ASP 5   ? OD1 ? C ASP 15  OD1 
89  1 Y 1 B ASP 5   ? OD2 ? C ASP 15  OD2 
90  1 Y 1 B GLN 6   ? CG  ? C GLN 16  CG  
91  1 Y 1 B GLN 6   ? CD  ? C GLN 16  CD  
92  1 Y 1 B GLN 6   ? OE1 ? C GLN 16  OE1 
93  1 Y 1 B GLN 6   ? NE2 ? C GLN 16  NE2 
94  1 Y 1 B LEU 7   ? CG  ? C LEU 17  CG  
95  1 Y 1 B LEU 7   ? CD1 ? C LEU 17  CD1 
96  1 Y 1 B LEU 7   ? CD2 ? C LEU 17  CD2 
97  1 Y 1 B GLN 9   ? CG  ? C GLN 19  CG  
98  1 Y 1 B GLN 9   ? CD  ? C GLN 19  CD  
99  1 Y 1 B GLN 9   ? OE1 ? C GLN 19  OE1 
100 1 Y 1 B GLN 9   ? NE2 ? C GLN 19  NE2 
101 1 Y 1 B ARG 19  ? CG  ? C ARG 29  CG  
102 1 Y 1 B ARG 19  ? CD  ? C ARG 29  CD  
103 1 Y 1 B ARG 19  ? NE  ? C ARG 29  NE  
104 1 Y 1 B ARG 19  ? CZ  ? C ARG 29  CZ  
105 1 Y 1 B ARG 19  ? NH1 ? C ARG 29  NH1 
106 1 Y 1 B ARG 19  ? NH2 ? C ARG 29  NH2 
107 1 Y 1 B LYS 23  ? CG  ? C LYS 33  CG  
108 1 Y 1 B LYS 23  ? CD  ? C LYS 33  CD  
109 1 Y 1 B LYS 23  ? CE  ? C LYS 33  CE  
110 1 Y 1 B LYS 23  ? NZ  ? C LYS 33  NZ  
111 1 Y 1 B GLU 172 ? CG  ? C GLU 182 CG  
112 1 Y 1 B GLU 172 ? CD  ? C GLU 182 CD  
113 1 Y 1 B GLU 172 ? OE1 ? C GLU 182 OE1 
114 1 Y 1 B GLU 172 ? OE2 ? C GLU 182 OE2 
115 1 Y 1 B ARG 197 ? CG  ? C ARG 207 CG  
116 1 Y 1 B ARG 197 ? CD  ? C ARG 207 CD  
117 1 Y 1 B ARG 197 ? NE  ? C ARG 207 NE  
118 1 Y 1 B ARG 197 ? CZ  ? C ARG 207 CZ  
119 1 Y 1 B ARG 197 ? NH1 ? C ARG 207 NH1 
120 1 Y 1 B ARG 197 ? NH2 ? C ARG 207 NH2 
121 1 Y 1 G GLN 11  ? CG  ? D GLN 11  CG  
122 1 Y 1 G GLN 11  ? CD  ? D GLN 11  CD  
123 1 Y 1 G GLN 11  ? OE1 ? D GLN 11  OE1 
124 1 Y 1 G GLN 11  ? NE2 ? D GLN 11  NE2 
125 1 Y 1 G ARG 13  ? CG  ? D ARG 13  CG  
126 1 Y 1 G ARG 13  ? CD  ? D ARG 13  CD  
127 1 Y 1 G ARG 13  ? NE  ? D ARG 13  NE  
128 1 Y 1 G ARG 13  ? CZ  ? D ARG 13  CZ  
129 1 Y 1 G ARG 13  ? NH1 ? D ARG 13  NH1 
130 1 Y 1 G ARG 13  ? NH2 ? D ARG 13  NH2 
131 1 Y 1 G GLU 17  ? CG  ? D GLU 17  CG  
132 1 Y 1 G GLU 17  ? CD  ? D GLU 17  CD  
133 1 Y 1 G GLU 17  ? OE1 ? D GLU 17  OE1 
134 1 Y 1 G GLU 17  ? OE2 ? D GLU 17  OE2 
135 1 Y 1 G MET 21  ? CG  ? D MET 21  CG  
136 1 Y 1 G MET 21  ? SD  ? D MET 21  SD  
137 1 Y 1 G MET 21  ? CE  ? D MET 21  CE  
138 1 Y 1 G ASP 26  ? CG  ? D ASP 26  CG  
139 1 Y 1 G ASP 26  ? OD1 ? D ASP 26  OD1 
140 1 Y 1 G ASP 26  ? OD2 ? D ASP 26  OD2 
141 1 Y 1 G GLU 58  ? CG  ? D GLU 58  CG  
142 1 Y 1 G GLU 58  ? CD  ? D GLU 58  CD  
143 1 Y 1 G GLU 58  ? OE1 ? D GLU 58  OE1 
144 1 Y 1 G GLU 58  ? OE2 ? D GLU 58  OE2 
145 1 Y 1 S GLU 89  ? CG  ? E GLU 89  CG  
146 1 Y 1 S GLU 89  ? CD  ? E GLU 89  CD  
147 1 Y 1 S GLU 89  ? OE1 ? E GLU 89  OE1 
148 1 Y 1 S GLU 89  ? OE2 ? E GLU 89  OE2 
149 1 Y 1 S THR 138 ? OG1 ? E THR 150 OG1 
150 1 Y 1 S THR 138 ? CG2 ? E THR 150 CG2 
151 1 Y 1 S GLU 141 ? CG  ? E GLU 153 CG  
152 1 Y 1 S GLU 141 ? CD  ? E GLU 153 CD  
153 1 Y 1 S GLU 141 ? OE1 ? E GLU 153 OE1 
154 1 Y 1 S GLU 141 ? OE2 ? E GLU 153 OE2 
155 1 Y 1 S ASP 189 ? CG  ? E ASP 201 CG  
156 1 Y 1 S ASP 189 ? OD1 ? E ASP 201 OD1 
157 1 Y 1 S ASP 189 ? OD2 ? E ASP 201 OD2 
158 1 Y 1 S ARG 206 ? CG  ? E ARG 218 CG  
159 1 Y 1 S ARG 206 ? CD  ? E ARG 218 CD  
160 1 Y 1 S ARG 206 ? NE  ? E ARG 218 NE  
161 1 Y 1 S ARG 206 ? CZ  ? E ARG 218 CZ  
162 1 Y 1 S ARG 206 ? NH1 ? E ARG 218 NH1 
163 1 Y 1 S ARG 206 ? NH2 ? E ARG 218 NH2 
164 1 Y 1 S GLU 208 ? CG  ? E GLU 220 CG  
165 1 Y 1 S GLU 208 ? CD  ? E GLU 220 CD  
166 1 Y 1 S GLU 208 ? OE1 ? E GLU 220 OE1 
167 1 Y 1 S GLU 208 ? OE2 ? E GLU 220 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XXR 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XXR 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XXR 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8XXR 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 8854  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.592 ? 12018 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.816 ? 1220  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 1393  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 1518  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8XXR 
_struct.title                        'Structure of CXCR2 bound to CXCL6 (CXCR2-CXCL6-Go Full map)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XXR 
_struct_keywords.text            'GPCR, Arrestin, SIGNALING PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CXCR2_HUMAN P25025 ? 1 
;EDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRS
VTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL
VKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKA
HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKF
RHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
;
2   
2 UNP GNAO_HUMAN  P09471 ? 2 TLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMKIIH 4   
3 UNP GNAO_HUMAN  P09471 ? 2 
;TTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQVLHEDETTNRMHESLMLFDSICNNKFFI
DTSIILFLNKKDLFGEKIKKSPLTICFPEYTGPNTYEDAAAYIQAQFESKNRSPNKEIYCHMTCATDTNNIQVVFDAVTD
IIIANNLRGCGLY
;
182 
4 UNP GBB1_HUMAN  P62873 ? 3 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2   
5 UNP GBG2_HUMAN  P59768 ? 4 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
6 PDB 8XXR        8XXR   ? 5 ? 1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XXR R 58 ? 416 ? P25025 2   ? 360 ? 2   360 
2 2 8XXR A 16 ? 69  ? P09471 4   ? 57  ? 4   173 
3 3 8XXR A 78 ? 240 ? P09471 182 ? 354 ? 182 354 
4 4 8XXR B 12 ? 350 ? P62873 2   ? 340 ? 2   340 
5 5 8XXR G 1  ? 71  ? P59768 1   ? 71  ? 1   71  
6 6 8XXR S 1  ? 248 ? 8XXR   1   ? 236 ? 1   236 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XXR MET R 1   ? UNP P25025 ?   ?   'initiating methionine' -55 1   
1 8XXR GLY R 2   ? UNP P25025 ?   ?   'expression tag'        -54 2   
1 8XXR LYS R 3   ? UNP P25025 ?   ?   'expression tag'        -53 3   
1 8XXR THR R 4   ? UNP P25025 ?   ?   'expression tag'        -52 4   
1 8XXR ILE R 5   ? UNP P25025 ?   ?   'expression tag'        -51 5   
1 8XXR ILE R 6   ? UNP P25025 ?   ?   'expression tag'        -50 6   
1 8XXR ALA R 7   ? UNP P25025 ?   ?   'expression tag'        -49 7   
1 8XXR LEU R 8   ? UNP P25025 ?   ?   'expression tag'        -48 8   
1 8XXR SER R 9   ? UNP P25025 ?   ?   'expression tag'        -47 9   
1 8XXR TYR R 10  ? UNP P25025 ?   ?   'expression tag'        -46 10  
1 8XXR ILE R 11  ? UNP P25025 ?   ?   'expression tag'        -45 11  
1 8XXR PHE R 12  ? UNP P25025 ?   ?   'expression tag'        -44 12  
1 8XXR CYS R 13  ? UNP P25025 ?   ?   'expression tag'        -43 13  
1 8XXR LEU R 14  ? UNP P25025 ?   ?   'expression tag'        -42 14  
1 8XXR VAL R 15  ? UNP P25025 ?   ?   'expression tag'        -41 15  
1 8XXR PHE R 16  ? UNP P25025 ?   ?   'expression tag'        -40 16  
1 8XXR ALA R 17  ? UNP P25025 ?   ?   'expression tag'        -39 17  
1 8XXR ASP R 18  ? UNP P25025 ?   ?   'expression tag'        -38 18  
1 8XXR TYR R 19  ? UNP P25025 ?   ?   'expression tag'        -37 19  
1 8XXR LYS R 20  ? UNP P25025 ?   ?   'expression tag'        -36 20  
1 8XXR ASP R 21  ? UNP P25025 ?   ?   'expression tag'        -35 21  
1 8XXR ASP R 22  ? UNP P25025 ?   ?   'expression tag'        -34 22  
1 8XXR ASP R 23  ? UNP P25025 ?   ?   'expression tag'        -33 23  
1 8XXR ASP R 24  ? UNP P25025 ?   ?   'expression tag'        -32 24  
1 8XXR ALA R 25  ? UNP P25025 ?   ?   'expression tag'        -31 25  
1 8XXR ALA R 26  ? UNP P25025 ?   ?   'expression tag'        -30 26  
1 8XXR ASN R 27  ? UNP P25025 ?   ?   'expression tag'        -29 27  
1 8XXR PHE R 28  ? UNP P25025 ?   ?   'expression tag'        -28 28  
1 8XXR THR R 29  ? UNP P25025 ?   ?   'expression tag'        -27 29  
1 8XXR PRO R 30  ? UNP P25025 ?   ?   'expression tag'        -26 30  
1 8XXR VAL R 31  ? UNP P25025 ?   ?   'expression tag'        -25 31  
1 8XXR ASN R 32  ? UNP P25025 ?   ?   'expression tag'        -24 32  
1 8XXR GLY R 33  ? UNP P25025 ?   ?   'expression tag'        -23 33  
1 8XXR SER R 34  ? UNP P25025 ?   ?   'expression tag'        -22 34  
1 8XXR SER R 35  ? UNP P25025 ?   ?   'expression tag'        -21 35  
1 8XXR GLY R 36  ? UNP P25025 ?   ?   'expression tag'        -20 36  
1 8XXR ASN R 37  ? UNP P25025 ?   ?   'expression tag'        -19 37  
1 8XXR GLN R 38  ? UNP P25025 ?   ?   'expression tag'        -18 38  
1 8XXR SER R 39  ? UNP P25025 ?   ?   'expression tag'        -17 39  
1 8XXR VAL R 40  ? UNP P25025 ?   ?   'expression tag'        -16 40  
1 8XXR ARG R 41  ? UNP P25025 ?   ?   'expression tag'        -15 41  
1 8XXR LEU R 42  ? UNP P25025 ?   ?   'expression tag'        -14 42  
1 8XXR VAL R 43  ? UNP P25025 ?   ?   'expression tag'        -13 43  
1 8XXR THR R 44  ? UNP P25025 ?   ?   'expression tag'        -12 44  
1 8XXR SER R 45  ? UNP P25025 ?   ?   'expression tag'        -11 45  
1 8XXR SER R 46  ? UNP P25025 ?   ?   'expression tag'        -10 46  
1 8XXR SER R 47  ? UNP P25025 ?   ?   'expression tag'        -9  47  
1 8XXR LEU R 48  ? UNP P25025 ?   ?   'expression tag'        -8  48  
1 8XXR GLU R 49  ? UNP P25025 ?   ?   'expression tag'        -7  49  
1 8XXR VAL R 50  ? UNP P25025 ?   ?   'expression tag'        -6  50  
1 8XXR LEU R 51  ? UNP P25025 ?   ?   'expression tag'        -5  51  
1 8XXR PHE R 52  ? UNP P25025 ?   ?   'expression tag'        -4  52  
1 8XXR GLN R 53  ? UNP P25025 ?   ?   'expression tag'        -3  53  
1 8XXR GLY R 54  ? UNP P25025 ?   ?   'expression tag'        -2  54  
1 8XXR PRO R 55  ? UNP P25025 ?   ?   'expression tag'        -1  55  
1 8XXR GLY R 56  ? UNP P25025 ?   ?   'expression tag'        0   56  
1 8XXR SER R 57  ? UNP P25025 ?   ?   'expression tag'        1   57  
2 8XXR MET A 1   ? UNP P09471 ?   ?   'initiating methionine' -11 58  
2 8XXR GLY A 2   ? UNP P09471 ?   ?   'expression tag'        -10 59  
2 8XXR HIS A 3   ? UNP P09471 ?   ?   'expression tag'        -9  60  
2 8XXR HIS A 4   ? UNP P09471 ?   ?   'expression tag'        -8  61  
2 8XXR HIS A 5   ? UNP P09471 ?   ?   'expression tag'        -7  62  
2 8XXR HIS A 6   ? UNP P09471 ?   ?   'expression tag'        -6  63  
2 8XXR HIS A 7   ? UNP P09471 ?   ?   'expression tag'        -5  64  
2 8XXR HIS A 8   ? UNP P09471 ?   ?   'expression tag'        -4  65  
2 8XXR GLU A 9   ? UNP P09471 ?   ?   'expression tag'        -3  66  
2 8XXR ASN A 10  ? UNP P09471 ?   ?   'expression tag'        -2  67  
2 8XXR LEU A 11  ? UNP P09471 ?   ?   'expression tag'        -1  68  
2 8XXR TYR A 12  ? UNP P09471 ?   ?   'expression tag'        0   69  
2 8XXR PHE A 13  ? UNP P09471 ?   ?   'expression tag'        1   70  
2 8XXR GLN A 14  ? UNP P09471 ?   ?   'expression tag'        2   71  
2 8XXR GLY A 15  ? UNP P09471 ?   ?   'expression tag'        3   72  
2 8XXR ASP A 54  ? UNP P09471 GLY 42  'engineered mutation'   42  73  
2 8XXR ASN A 55  ? UNP P09471 GLU 43  'engineered mutation'   43  74  
2 8XXR GLY A 70  ? UNP P09471 ?   ?   linker                  174 75  
2 8XXR GLY A 71  ? UNP P09471 ?   ?   linker                  175 76  
2 8XXR SER A 72  ? UNP P09471 ?   ?   linker                  176 77  
2 8XXR GLY A 73  ? UNP P09471 ?   ?   linker                  177 78  
2 8XXR GLY A 74  ? UNP P09471 ?   ?   linker                  178 79  
2 8XXR SER A 75  ? UNP P09471 ?   ?   linker                  179 80  
2 8XXR GLY A 76  ? UNP P09471 ?   ?   linker                  180 81  
2 8XXR GLY A 77  ? UNP P09471 ?   ?   linker                  181 82  
3 8XXR ASP A 123 ? UNP P09471 ALA 227 'engineered mutation'   227 83  
3 8XXR ASP A 126 ? UNP P09471 GLY 230 'engineered mutation'   240 84  
3 8XXR ?   A ?   ? UNP P09471 ASP 232 deletion                ?   85  
3 8XXR ?   A ?   ? UNP P09471 GLN 233 deletion                ?   86  
3 8XXR ?   A ?   ? UNP P09471 VAL 234 deletion                ?   87  
3 8XXR ?   A ?   ? UNP P09471 LEU 235 deletion                ?   88  
3 8XXR ?   A ?   ? UNP P09471 HIS 236 deletion                ?   89  
3 8XXR ?   A ?   ? UNP P09471 GLU 237 deletion                ?   90  
3 8XXR ?   A ?   ? UNP P09471 ASP 238 deletion                ?   91  
3 8XXR ?   A ?   ? UNP P09471 GLU 239 deletion                ?   92  
3 8XXR ?   A ?   ? UNP P09471 THR 240 deletion                ?   93  
3 8XXR ?   A ?   ? UNP P09471 THR 241 deletion                ?   94  
3 8XXR ALA A 218 ? UNP P09471 ILE 332 'engineered mutation'   332 95  
3 8XXR ILE A 221 ? UNP P09471 VAL 335 'engineered mutation'   335 96  
4 8XXR MET B 1   ? UNP P62873 ?   ?   'initiating methionine' -9  97  
4 8XXR HIS B 2   ? UNP P62873 ?   ?   'expression tag'        -8  98  
4 8XXR HIS B 3   ? UNP P62873 ?   ?   'expression tag'        -7  99  
4 8XXR HIS B 4   ? UNP P62873 ?   ?   'expression tag'        -6  100 
4 8XXR HIS B 5   ? UNP P62873 ?   ?   'expression tag'        -5  101 
4 8XXR HIS B 6   ? UNP P62873 ?   ?   'expression tag'        -4  102 
4 8XXR HIS B 7   ? UNP P62873 ?   ?   'expression tag'        -3  103 
4 8XXR GLY B 8   ? UNP P62873 ?   ?   'expression tag'        -2  104 
4 8XXR SER B 9   ? UNP P62873 ?   ?   'expression tag'        -1  105 
4 8XXR SER B 10  ? UNP P62873 ?   ?   'expression tag'        0   106 
4 8XXR GLY B 11  ? UNP P62873 ?   ?   'expression tag'        1   107 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 100 ? SER A 132 ? LEU R 44  SER R 76  1 ? 33 
HELX_P HELX_P2  AA2 SER A 137 ? GLY A 167 ? SER R 81  GLY R 111 1 ? 31 
HELX_P HELX_P3  AA3 GLY A 171 ? VAL A 205 ? GLY R 115 VAL R 149 1 ? 35 
HELX_P HELX_P4  AA4 ARG A 209 ? TYR A 216 ? ARG R 153 TYR R 160 5 ? 8  
HELX_P HELX_P5  AA5 LEU A 217 ? PHE A 239 ? LEU R 161 PHE R 183 1 ? 23 
HELX_P HELX_P6  AA6 ASN A 259 ? ARG A 268 ? ASN R 203 ARG R 212 1 ? 10 
HELX_P HELX_P7  AA7 PHE A 276 ? LYS A 296 ? PHE R 220 LYS R 240 1 ? 21 
HELX_P HELX_P8  AA8 GLN A 301 ? THR A 335 ? GLN R 245 THR R 279 1 ? 35 
HELX_P HELX_P9  AA9 THR A 341 ? LEU A 361 ? THR R 285 LEU R 305 1 ? 21 
HELX_P HELX_P10 AB1 LEU A 361 ? ALA A 371 ? LEU R 305 ALA R 315 1 ? 11 
HELX_P HELX_P11 AB2 GLY A 374 ? LEU A 385 ? GLY R 318 LEU R 329 1 ? 12 
HELX_P HELX_P12 AB3 SER B 18  ? ALA B 42  ? SER A 6   ALA A 30  1 ? 25 
HELX_P HELX_P13 AB4 GLU B 104 ? GLU B 113 ? GLU A 208 GLU A 217 5 ? 10 
HELX_P HELX_P14 AB5 GLU B 132 ? ASN B 142 ? GLU A 246 ASN A 256 1 ? 11 
HELX_P HELX_P15 AB6 LYS B 157 ? SER B 168 ? LYS A 271 SER A 282 1 ? 12 
HELX_P HELX_P16 AB7 THR B 182 ? SER B 196 ? THR A 296 SER A 310 1 ? 15 
HELX_P HELX_P17 AB8 ASN B 216 ? CYS B 237 ? ASN A 330 CYS A 351 1 ? 22 
HELX_P HELX_P18 AB9 GLN C 16  ? ALA C 36  ? GLN B 6   ALA B 26  1 ? 21 
HELX_P HELX_P19 AC1 THR C 39  ? THR C 44  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P20 AC2 ALA D 12  ? ASN D 24  ? ALA G 12  ASN G 24  1 ? 13 
HELX_P HELX_P21 AC3 LYS D 29  ? HIS D 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P22 AC4 PRO D 55  ? ASN D 59  ? PRO G 55  ASN G 59  5 ? 5  
HELX_P HELX_P23 AC5 ALA E 28  ? PHE E 32  ? ALA S 28  PHE S 32  5 ? 5  
HELX_P HELX_P24 AC6 SER E 53  ? GLY E 56  ? SER S 53  GLY S 56  5 ? 4  
HELX_P HELX_P25 AC7 GLU E 220 ? VAL E 224 ? GLU S 208 VAL S 212 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 95  SG ? ? ? 1_555 A CYS 342 SG ? ? R CYS 39  R CYS 286 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? A CYS 175 SG ? ? ? 1_555 A CYS 252 SG ? ? R CYS 119 R CYS 196 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ? ? E CYS 22  SG ? ? ? 1_555 E CYS 96  SG ? ? S CYS 22  S CYS 96  1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf4 disulf ? ? E CYS 159 SG ? ? ? 1_555 E CYS 229 SG ? ? S CYS 147 S CYS 217 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 95  ? CYS A 342 ? CYS R 39  ? 1_555 CYS R 286 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 175 ? CYS A 252 ? CYS R 119 ? 1_555 CYS R 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 22  ? CYS E 96  ? CYS S 22  ? 1_555 CYS S 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS E 159 ? CYS E 229 ? CYS S 147 ? 1_555 CYS S 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          E 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           S 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   E 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    S 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -0.06 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 3 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 6 ? 
AB4 ? 4 ? 
AB5 ? 5 ? 
AB6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB3 5 6 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB6 1 2 ? parallel      
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 240 ? VAL A 243 ? ARG R 184 VAL R 187 
AA1 2 ALA A 251 ? GLU A 254 ? ALA R 195 GLU R 198 
AA2 1 VAL B 82  ? THR B 84  ? VAL A 186 THR A 188 
AA2 2 LEU B 91  ? ASP B 97  ? LEU A 195 ASP A 201 
AA2 3 THR B 87  ? PHE B 88  ? THR A 191 PHE A 192 
AA3 1 VAL B 82  ? THR B 84  ? VAL A 186 THR A 188 
AA3 2 LEU B 91  ? ASP B 97  ? LEU A 195 ASP A 201 
AA3 3 ASP B 45  ? GLY B 52  ? ASP A 33  GLY A 40  
AA3 4 ALA B 117 ? ASP B 123 ? ALA A 221 ASP A 227 
AA3 5 ILE B 151 ? ASN B 156 ? ILE A 265 ASN A 270 
AA3 6 ILE B 205 ? MET B 209 ? ILE A 319 MET A 323 
AA4 1 THR C 57  ? LEU C 61  ? THR B 47  LEU B 51  
AA4 2 LEU C 346 ? TRP C 349 ? LEU B 336 TRP B 339 
AA4 3 VAL C 337 ? SER C 341 ? VAL B 327 SER B 331 
AA4 4 VAL C 325 ? VAL C 330 ? VAL B 315 VAL B 320 
AA5 1 ILE C 68  ? TRP C 73  ? ILE B 58  TRP B 63  
AA5 2 LEU C 80  ? SER C 84  ? LEU B 70  SER B 74  
AA5 3 LYS C 88  ? ASP C 93  ? LYS B 78  ASP B 83  
AA5 4 ASN C 98  ? PRO C 104 ? ASN B 88  PRO B 94  
AA6 1 VAL C 110 ? TYR C 115 ? VAL B 100 TYR B 105 
AA6 2 TYR C 121 ? GLY C 126 ? TYR B 111 GLY B 116 
AA6 3 CYS C 131 ? ASN C 135 ? CYS B 121 ASN B 125 
AA6 4 ARG C 144 ? LEU C 149 ? ARG B 134 LEU B 139 
AA7 1 LEU C 156 ? ASP C 163 ? LEU B 146 ASP B 153 
AA7 2 GLN C 166 ? SER C 171 ? GLN B 156 SER B 161 
AA7 3 THR C 175 ? ASP C 180 ? THR B 165 ASP B 170 
AA7 4 GLN C 186 ? THR C 191 ? GLN B 176 THR B 181 
AA8 1 VAL C 197 ? LEU C 202 ? VAL B 187 LEU B 192 
AA8 2 LEU C 208 ? ALA C 213 ? LEU B 198 ALA B 203 
AA8 3 SER C 217 ? ASP C 222 ? SER B 207 ASP B 212 
AA8 4 CYS C 228 ? THR C 233 ? CYS B 218 THR B 223 
AA9 1 ILE C 239 ? PHE C 244 ? ILE B 229 PHE B 234 
AA9 2 ALA C 250 ? SER C 255 ? ALA B 240 SER B 245 
AA9 3 CYS C 260 ? ASP C 264 ? CYS B 250 ASP B 254 
AA9 4 GLU C 270 ? THR C 273 ? GLU B 260 THR B 263 
AB1 1 ILE C 283 ? SER C 287 ? ILE B 273 SER B 277 
AB1 2 LEU C 294 ? TYR C 299 ? LEU B 284 TYR B 289 
AB1 3 CYS C 304 ? ASP C 308 ? CYS B 294 ASP B 298 
AB1 4 ARG C 314 ? VAL C 317 ? ARG B 304 VAL B 307 
AB2 1 GLN E 3   ? SER E 7   ? GLN S 3   SER S 7   
AB2 2 ARG E 18  ? SER E 25  ? ARG S 18  SER S 25  
AB2 3 THR E 78  ? MET E 83  ? THR S 78  MET S 83  
AB2 4 PHE E 68  ? ASP E 73  ? PHE S 68  ASP S 73  
AB3 1 LEU E 11  ? VAL E 12  ? LEU S 11  VAL S 12  
AB3 2 THR E 115 ? VAL E 119 ? THR S 115 VAL S 119 
AB3 3 ALA E 92  ? SER E 99  ? ALA S 92  SER S 99  
AB3 4 GLY E 33  ? ALA E 40  ? GLY S 33  ALA S 40  
AB3 5 GLY E 44  ? ILE E 51  ? GLY S 44  ILE S 51  
AB3 6 ILE E 58  ? TYR E 60  ? ILE S 58  TYR S 60  
AB4 1 MET E 140 ? GLN E 142 ? MET S 128 GLN S 130 
AB4 2 VAL E 155 ? SER E 161 ? VAL S 143 SER S 149 
AB4 3 ALA E 211 ? ILE E 216 ? ALA S 199 ILE S 204 
AB4 4 PHE E 203 ? SER E 208 ? PHE S 191 SER S 196 
AB5 1 SER E 146 ? PRO E 148 ? SER S 134 PRO S 136 
AB5 2 THR E 243 ? GLU E 246 ? THR S 231 GLU S 234 
AB5 3 VAL E 226 ? GLN E 231 ? VAL S 214 GLN S 219 
AB5 4 LEU E 174 ? GLN E 179 ? LEU S 162 GLN S 167 
AB5 5 GLN E 186 ? ILE E 189 ? GLN S 174 ILE S 177 
AB6 1 SER E 146 ? PRO E 148 ? SER S 134 PRO S 136 
AB6 2 THR E 243 ? GLU E 246 ? THR S 231 GLU S 234 
AB6 3 VAL E 226 ? GLN E 231 ? VAL S 214 GLN S 219 
AB6 4 THR E 238 ? PHE E 239 ? THR S 226 PHE S 227 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG A 241 ? N ARG R 185 O TYR A 253 ? O TYR R 197 
AA2 1 2 N THR B 84  ? N THR A 188 O LEU B 95  ? O LEU A 199 
AA2 2 3 O LEU B 91  ? O LEU A 195 N PHE B 88  ? N PHE A 192 
AA3 1 2 N THR B 84  ? N THR A 188 O LEU B 95  ? O LEU A 199 
AA3 2 3 O HIS B 92  ? O HIS A 196 N VAL B 46  ? N VAL A 34  
AA3 3 4 N LEU B 49  ? N LEU A 37  O ILE B 119 ? O ILE A 223 
AA3 4 5 N ILE B 118 ? N ILE A 222 O ILE B 152 ? O ILE A 266 
AA3 5 6 N LEU B 153 ? N LEU A 267 O TYR B 206 ? O TYR A 320 
AA4 1 2 N LEU C 61  ? N LEU B 51  O LEU C 346 ? O LEU B 336 
AA4 2 3 O TRP C 349 ? O TRP B 339 N VAL C 337 ? N VAL B 327 
AA4 3 4 O ALA C 338 ? O ALA B 328 N GLY C 329 ? N GLY B 319 
AA5 1 2 N HIS C 72  ? N HIS B 62  O VAL C 81  ? O VAL B 71  
AA5 2 3 N SER C 82  ? N SER B 72  O ILE C 90  ? O ILE B 80  
AA5 3 4 N LEU C 89  ? N LEU B 79  O ILE C 103 ? O ILE B 93  
AA6 1 2 N THR C 112 ? N THR B 102 O GLY C 125 ? O GLY B 115 
AA6 2 3 N CYS C 124 ? N CYS B 114 O SER C 132 ? O SER B 122 
AA6 3 4 N ASN C 135 ? N ASN B 125 O ARG C 144 ? O ARG B 134 
AA7 1 2 N SER C 157 ? N SER B 147 O SER C 170 ? O SER B 160 
AA7 2 3 N ILE C 167 ? N ILE B 157 O TRP C 179 ? O TRP B 169 
AA7 3 4 N CYS C 176 ? N CYS B 166 O PHE C 190 ? O PHE B 180 
AA8 1 2 N SER C 199 ? N SER B 189 O GLY C 212 ? O GLY B 202 
AA8 2 3 N PHE C 209 ? N PHE B 199 O TRP C 221 ? O TRP B 211 
AA8 3 4 N ALA C 218 ? N ALA B 208 O PHE C 232 ? O PHE B 222 
AA9 1 2 N ASN C 240 ? N ASN B 230 O GLY C 254 ? O GLY B 244 
AA9 2 3 N PHE C 251 ? N PHE B 241 O PHE C 263 ? O PHE B 253 
AA9 3 4 N LEU C 262 ? N LEU B 252 O LEU C 271 ? O LEU B 261 
AB1 1 2 N THR C 284 ? N THR B 274 O GLY C 298 ? O GLY B 288 
AB1 2 3 N LEU C 295 ? N LEU B 285 O TRP C 307 ? O TRP B 297 
AB1 3 4 N VAL C 306 ? N VAL B 296 O ALA C 315 ? O ALA B 305 
AB2 1 2 N VAL E 5   ? N VAL S 5   O SER E 23  ? O SER S 23  
AB2 2 3 N CYS E 22  ? N CYS S 22  O LEU E 79  ? O LEU S 79  
AB2 3 4 O GLN E 82  ? O GLN S 82  N THR E 69  ? N THR S 69  
AB3 1 2 N VAL E 12  ? N VAL S 12  O THR E 118 ? O THR S 118 
AB3 2 3 O THR E 115 ? O THR S 115 N TYR E 94  ? N TYR S 94  
AB3 3 4 O TYR E 95  ? O TYR S 95  N VAL E 37  ? N VAL S 37  
AB3 4 5 N MET E 34  ? N MET S 34  O ILE E 51  ? O ILE S 51  
AB3 5 6 N TYR E 50  ? N TYR S 50  O TYR E 59  ? O TYR S 59  
AB4 1 2 N THR E 141 ? N THR S 129 O ARG E 160 ? O ARG S 148 
AB4 2 3 N ILE E 157 ? N ILE S 145 O LEU E 214 ? O LEU S 202 
AB4 3 4 O THR E 215 ? O THR S 203 N SER E 204 ? N SER S 192 
AB5 1 2 N VAL E 147 ? N VAL S 135 O GLU E 246 ? O GLU S 234 
AB5 2 3 O THR E 243 ? O THR S 231 N TYR E 227 ? N TYR S 215 
AB5 3 4 O TYR E 228 ? O TYR S 216 N PHE E 177 ? N PHE S 165 
AB5 4 5 N LEU E 178 ? N LEU S 166 O GLN E 186 ? O GLN S 174 
AB6 1 2 N VAL E 147 ? N VAL S 135 O GLU E 246 ? O GLU S 234 
AB6 2 3 O THR E 243 ? O THR S 231 N TYR E 227 ? N TYR S 215 
AB6 3 4 N GLN E 231 ? N GLN S 219 O THR E 238 ? O THR S 226 
# 
_pdbx_entry_details.entry_id                   8XXR 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASN R 110 ? ? -141.56 26.58   
2  1 LYS R 240 ? ? -94.69  31.24   
3  1 THR A 327 ? ? -94.67  56.60   
4  1 ASN B 119 ? ? 78.30   -2.57   
5  1 ALA B 299 ? ? -67.84  3.81    
6  1 ALA B 305 ? ? -93.03  52.98   
7  1 ALA B 309 ? ? 59.26   -154.55 
8  1 HIS G 44  ? ? -91.89  49.98   
9  1 VAL S 48  ? ? -122.40 -61.33  
10 1 PHE S 108 ? ? -142.54 33.00   
11 1 ARG S 179 ? ? -121.07 -67.10  
12 1 MET S 180 ? ? -135.33 -39.04  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8XXR 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   SwissModel 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    8XXR 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.17 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               61539 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'C-X-C chemokine receptor type 2 in complex with C-X-C motif chemokine 6 and Go' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_image_scans.entry_id                8XXR 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        40 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8XXR 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              8XXR 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8XXR 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 R MET -55 ? A MET 1   
2   1 Y 1 R GLY -54 ? A GLY 2   
3   1 Y 1 R LYS -53 ? A LYS 3   
4   1 Y 1 R THR -52 ? A THR 4   
5   1 Y 1 R ILE -51 ? A ILE 5   
6   1 Y 1 R ILE -50 ? A ILE 6   
7   1 Y 1 R ALA -49 ? A ALA 7   
8   1 Y 1 R LEU -48 ? A LEU 8   
9   1 Y 1 R SER -47 ? A SER 9   
10  1 Y 1 R TYR -46 ? A TYR 10  
11  1 Y 1 R ILE -45 ? A ILE 11  
12  1 Y 1 R PHE -44 ? A PHE 12  
13  1 Y 1 R CYS -43 ? A CYS 13  
14  1 Y 1 R LEU -42 ? A LEU 14  
15  1 Y 1 R VAL -41 ? A VAL 15  
16  1 Y 1 R PHE -40 ? A PHE 16  
17  1 Y 1 R ALA -39 ? A ALA 17  
18  1 Y 1 R ASP -38 ? A ASP 18  
19  1 Y 1 R TYR -37 ? A TYR 19  
20  1 Y 1 R LYS -36 ? A LYS 20  
21  1 Y 1 R ASP -35 ? A ASP 21  
22  1 Y 1 R ASP -34 ? A ASP 22  
23  1 Y 1 R ASP -33 ? A ASP 23  
24  1 Y 1 R ASP -32 ? A ASP 24  
25  1 Y 1 R ALA -31 ? A ALA 25  
26  1 Y 1 R ALA -30 ? A ALA 26  
27  1 Y 1 R ASN -29 ? A ASN 27  
28  1 Y 1 R PHE -28 ? A PHE 28  
29  1 Y 1 R THR -27 ? A THR 29  
30  1 Y 1 R PRO -26 ? A PRO 30  
31  1 Y 1 R VAL -25 ? A VAL 31  
32  1 Y 1 R ASN -24 ? A ASN 32  
33  1 Y 1 R GLY -23 ? A GLY 33  
34  1 Y 1 R SER -22 ? A SER 34  
35  1 Y 1 R SER -21 ? A SER 35  
36  1 Y 1 R GLY -20 ? A GLY 36  
37  1 Y 1 R ASN -19 ? A ASN 37  
38  1 Y 1 R GLN -18 ? A GLN 38  
39  1 Y 1 R SER -17 ? A SER 39  
40  1 Y 1 R VAL -16 ? A VAL 40  
41  1 Y 1 R ARG -15 ? A ARG 41  
42  1 Y 1 R LEU -14 ? A LEU 42  
43  1 Y 1 R VAL -13 ? A VAL 43  
44  1 Y 1 R THR -12 ? A THR 44  
45  1 Y 1 R SER -11 ? A SER 45  
46  1 Y 1 R SER -10 ? A SER 46  
47  1 Y 1 R SER -9  ? A SER 47  
48  1 Y 1 R LEU -8  ? A LEU 48  
49  1 Y 1 R GLU -7  ? A GLU 49  
50  1 Y 1 R VAL -6  ? A VAL 50  
51  1 Y 1 R LEU -5  ? A LEU 51  
52  1 Y 1 R PHE -4  ? A PHE 52  
53  1 Y 1 R GLN -3  ? A GLN 53  
54  1 Y 1 R GLY -2  ? A GLY 54  
55  1 Y 1 R PRO -1  ? A PRO 55  
56  1 Y 1 R GLY 0   ? A GLY 56  
57  1 Y 1 R SER 1   ? A SER 57  
58  1 Y 1 R GLU 2   ? A GLU 58  
59  1 Y 1 R ASP 3   ? A ASP 59  
60  1 Y 1 R PHE 4   ? A PHE 60  
61  1 Y 1 R ASN 5   ? A ASN 61  
62  1 Y 1 R MET 6   ? A MET 62  
63  1 Y 1 R GLU 7   ? A GLU 63  
64  1 Y 1 R SER 8   ? A SER 64  
65  1 Y 1 R ASP 9   ? A ASP 65  
66  1 Y 1 R SER 10  ? A SER 66  
67  1 Y 1 R PHE 11  ? A PHE 67  
68  1 Y 1 R GLU 12  ? A GLU 68  
69  1 Y 1 R ASP 13  ? A ASP 69  
70  1 Y 1 R PHE 14  ? A PHE 70  
71  1 Y 1 R TRP 15  ? A TRP 71  
72  1 Y 1 R LYS 16  ? A LYS 72  
73  1 Y 1 R GLY 17  ? A GLY 73  
74  1 Y 1 R GLU 18  ? A GLU 74  
75  1 Y 1 R ASP 19  ? A ASP 75  
76  1 Y 1 R LEU 20  ? A LEU 76  
77  1 Y 1 R SER 21  ? A SER 77  
78  1 Y 1 R ASN 22  ? A ASN 78  
79  1 Y 1 R TYR 23  ? A TYR 79  
80  1 Y 1 R SER 24  ? A SER 80  
81  1 Y 1 R TYR 25  ? A TYR 81  
82  1 Y 1 R SER 26  ? A SER 82  
83  1 Y 1 R SER 27  ? A SER 83  
84  1 Y 1 R THR 28  ? A THR 84  
85  1 Y 1 R LEU 29  ? A LEU 85  
86  1 Y 1 R PRO 30  ? A PRO 86  
87  1 Y 1 R PRO 31  ? A PRO 87  
88  1 Y 1 R PHE 32  ? A PHE 88  
89  1 Y 1 R LEU 33  ? A LEU 89  
90  1 Y 1 R LEU 34  ? A LEU 90  
91  1 Y 1 R ASP 35  ? A ASP 91  
92  1 Y 1 R ALA 36  ? A ALA 92  
93  1 Y 1 R ALA 37  ? A ALA 93  
94  1 Y 1 R ILE 331 ? A ILE 387 
95  1 Y 1 R HIS 332 ? A HIS 388 
96  1 Y 1 R GLY 333 ? A GLY 389 
97  1 Y 1 R LEU 334 ? A LEU 390 
98  1 Y 1 R ILE 335 ? A ILE 391 
99  1 Y 1 R SER 336 ? A SER 392 
100 1 Y 1 R LYS 337 ? A LYS 393 
101 1 Y 1 R ASP 338 ? A ASP 394 
102 1 Y 1 R SER 339 ? A SER 395 
103 1 Y 1 R LEU 340 ? A LEU 396 
104 1 Y 1 R PRO 341 ? A PRO 397 
105 1 Y 1 R LYS 342 ? A LYS 398 
106 1 Y 1 R ASP 343 ? A ASP 399 
107 1 Y 1 R SER 344 ? A SER 400 
108 1 Y 1 R ARG 345 ? A ARG 401 
109 1 Y 1 R PRO 346 ? A PRO 402 
110 1 Y 1 R SER 347 ? A SER 403 
111 1 Y 1 R PHE 348 ? A PHE 404 
112 1 Y 1 R VAL 349 ? A VAL 405 
113 1 Y 1 R GLY 350 ? A GLY 406 
114 1 Y 1 R SER 351 ? A SER 407 
115 1 Y 1 R SER 352 ? A SER 408 
116 1 Y 1 R SER 353 ? A SER 409 
117 1 Y 1 R GLY 354 ? A GLY 410 
118 1 Y 1 R HIS 355 ? A HIS 411 
119 1 Y 1 R THR 356 ? A THR 412 
120 1 Y 1 R SER 357 ? A SER 413 
121 1 Y 1 R THR 358 ? A THR 414 
122 1 Y 1 R THR 359 ? A THR 415 
123 1 Y 1 R LEU 360 ? A LEU 416 
124 1 Y 1 A MET -11 ? B MET 1   
125 1 Y 1 A GLY -10 ? B GLY 2   
126 1 Y 1 A HIS -9  ? B HIS 3   
127 1 Y 1 A HIS -8  ? B HIS 4   
128 1 Y 1 A HIS -7  ? B HIS 5   
129 1 Y 1 A HIS -6  ? B HIS 6   
130 1 Y 1 A HIS -5  ? B HIS 7   
131 1 Y 1 A HIS -4  ? B HIS 8   
132 1 Y 1 A GLU -3  ? B GLU 9   
133 1 Y 1 A ASN -2  ? B ASN 10  
134 1 Y 1 A LEU -1  ? B LEU 11  
135 1 Y 1 A TYR 0   ? B TYR 12  
136 1 Y 1 A PHE 1   ? B PHE 13  
137 1 Y 1 A GLN 2   ? B GLN 14  
138 1 Y 1 A GLY 3   ? B GLY 15  
139 1 Y 1 A HIS 173 ? B HIS 69  
140 1 Y 1 A GLY 174 ? B GLY 70  
141 1 Y 1 A GLY 175 ? B GLY 71  
142 1 Y 1 A SER 176 ? B SER 72  
143 1 Y 1 A GLY 177 ? B GLY 73  
144 1 Y 1 A GLY 178 ? B GLY 74  
145 1 Y 1 A SER 179 ? B SER 75  
146 1 Y 1 A GLY 180 ? B GLY 76  
147 1 Y 1 A GLY 181 ? B GLY 77  
148 1 Y 1 A THR 182 ? B THR 78  
149 1 Y 1 A ASP 240 ? B ASP 126 
150 1 Y 1 A TYR 241 ? B TYR 127 
151 1 Y 1 A ASN 242 ? B ASN 128 
152 1 Y 1 A ARG 243 ? B ARG 129 
153 1 Y 1 A MET 244 ? B MET 130 
154 1 Y 1 B MET -9  ? C MET 1   
155 1 Y 1 B HIS -8  ? C HIS 2   
156 1 Y 1 B HIS -7  ? C HIS 3   
157 1 Y 1 B HIS -6  ? C HIS 4   
158 1 Y 1 B HIS -5  ? C HIS 5   
159 1 Y 1 B HIS -4  ? C HIS 6   
160 1 Y 1 B HIS -3  ? C HIS 7   
161 1 Y 1 B GLY -2  ? C GLY 8   
162 1 Y 1 B SER -1  ? C SER 9   
163 1 Y 1 B SER 0   ? C SER 10  
164 1 Y 1 B GLY 1   ? C GLY 11  
165 1 Y 1 B SER 2   ? C SER 12  
166 1 Y 1 B GLU 3   ? C GLU 13  
167 1 Y 1 B LEU 4   ? C LEU 14  
168 1 Y 1 G MET 1   ? D MET 1   
169 1 Y 1 G ALA 2   ? D ALA 2   
170 1 Y 1 G SER 3   ? D SER 3   
171 1 Y 1 G ASN 4   ? D ASN 4   
172 1 Y 1 G ASN 5   ? D ASN 5   
173 1 Y 1 G THR 6   ? D THR 6   
174 1 Y 1 G ALA 7   ? D ALA 7   
175 1 Y 1 G SER 8   ? D SER 8   
176 1 Y 1 G ARG 62  ? D ARG 62  
177 1 Y 1 G GLU 63  ? D GLU 63  
178 1 Y 1 G LYS 64  ? D LYS 64  
179 1 Y 1 G LYS 65  ? D LYS 65  
180 1 Y 1 G PHE 66  ? D PHE 66  
181 1 Y 1 G PHE 67  ? D PHE 67  
182 1 Y 1 G CYS 68  ? D CYS 68  
183 1 Y 1 G ALA 69  ? D ALA 69  
184 1 Y 1 G ILE 70  ? D ILE 70  
185 1 Y 1 G LEU 71  ? D LEU 71  
186 1 Y 1 S GLY 121 A E GLY 122 
187 1 Y 1 S GLY 121 B E GLY 123 
188 1 Y 1 S GLY 121 C E GLY 124 
189 1 Y 1 S GLY 121 D E GLY 125 
190 1 Y 1 S SER 121 E E SER 126 
191 1 Y 1 S GLY 121 F E GLY 127 
192 1 Y 1 S GLY 121 G E GLY 128 
193 1 Y 1 S GLY 121 H E GLY 129 
194 1 Y 1 S GLY 121 I E GLY 130 
195 1 Y 1 S SER 121 J E SER 131 
196 1 Y 1 S GLY 121 K E GLY 132 
197 1 Y 1 S GLY 121 L E GLY 133 
198 1 Y 1 S GLY 121 M E GLY 134 
199 1 Y 1 S GLY 121 N E GLY 135 
200 1 Y 1 S LYS 236 ? E LYS 248 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-18 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8XXR 
_em_admin.last_update        2025-04-09 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'Structure of CXCR2 bound to CXCL6 (CXCR2-CXCL6-Go Full map)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1609421 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?         ?   
MASKING                         ? 3  ? ? ? ?         ?   
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC 4.4 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?   
'MODEL FITTING'                 ? 7  ? 1 ? Coot      ?   
OTHER                           ? 8  ? ? ? ?         ?   
'MODEL REFINEMENT'              ? 9  ? 1 ? PHENIX    ?   
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?         ?   
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?         ?   
CLASSIFICATION                  ? 12 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION                  ? 13 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION                  ? 14 1 ? ? RELION    4   
'VOLUME SELECTION'              ? 15 1 1 1 ?         ?   
'SERIES ALIGNMENT'              ? 16 1 1 1 ?         ?   
'MOLECULAR REPLACEMENT'         ? 17 1 1 1 ?         ?   
'LATTICE DISTORTION CORRECTION' ? 18 1 1 1 ?         ?   
'SYMMETRY DETERMINATION'        ? 19 1 1 1 ?         ?   
'CRYSTALLOGRAPHY MERGING'       ? 20 1 1 1 ?         ?   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Science and Engineering Research Board (SERB)' 
_pdbx_audit_support.country                India 
_pdbx_audit_support.grant_number           IPA/2020/000405 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      SwissModel 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8XXR 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . PRO A 1 94  ? 115.252 137.823 64.656  1.00 140.68 ? 38  PRO R N   1 
ATOM 2    C CA  . PRO A 1 94  ? 115.155 137.840 66.120  1.00 140.29 ? 38  PRO R CA  1 
ATOM 3    C C   . PRO A 1 94  ? 114.993 136.443 66.711  1.00 140.39 ? 38  PRO R C   1 
ATOM 4    O O   . PRO A 1 94  ? 114.602 135.517 66.002  1.00 140.00 ? 38  PRO R O   1 
ATOM 5    C CB  . PRO A 1 94  ? 113.906 138.689 66.380  1.00 138.59 ? 38  PRO R CB  1 
ATOM 6    C CG  . PRO A 1 94  ? 113.751 139.523 65.156  1.00 139.87 ? 38  PRO R CG  1 
ATOM 7    C CD  . PRO A 1 94  ? 114.219 138.661 64.025  1.00 139.76 ? 38  PRO R CD  1 
ATOM 8    N N   . CYS A 1 95  ? 115.293 136.301 67.999  1.00 142.27 ? 39  CYS R N   1 
ATOM 9    C CA  . CYS A 1 95  ? 115.168 135.035 68.708  1.00 141.73 ? 39  CYS R CA  1 
ATOM 10   C C   . CYS A 1 95  ? 113.971 135.101 69.647  1.00 141.88 ? 39  CYS R C   1 
ATOM 11   O O   . CYS A 1 95  ? 113.856 136.034 70.449  1.00 141.37 ? 39  CYS R O   1 
ATOM 12   C CB  . CYS A 1 95  ? 116.443 134.717 69.492  1.00 141.32 ? 39  CYS R CB  1 
ATOM 13   S SG  . CYS A 1 95  ? 116.216 133.550 70.856  1.00 146.33 ? 39  CYS R SG  1 
ATOM 14   N N   . GLU A 1 96  ? 113.084 134.112 69.542  1.00 130.01 ? 40  GLU R N   1 
ATOM 15   C CA  . GLU A 1 96  ? 111.876 134.074 70.352  1.00 129.81 ? 40  GLU R CA  1 
ATOM 16   C C   . GLU A 1 96  ? 112.074 133.133 71.527  1.00 130.93 ? 40  GLU R C   1 
ATOM 17   O O   . GLU A 1 96  ? 112.305 131.932 71.311  1.00 130.40 ? 40  GLU R O   1 
ATOM 18   C CB  . GLU A 1 96  ? 110.684 133.625 69.514  1.00 128.00 ? 40  GLU R CB  1 
ATOM 19   N N   . PRO A 1 97  ? 112.002 133.614 72.769  1.00 126.33 ? 41  PRO R N   1 
ATOM 20   C CA  . PRO A 1 97  ? 112.105 132.704 73.919  1.00 125.19 ? 41  PRO R CA  1 
ATOM 21   C C   . PRO A 1 97  ? 110.901 131.775 73.985  1.00 124.24 ? 41  PRO R C   1 
ATOM 22   O O   . PRO A 1 97  ? 109.752 132.217 73.920  1.00 122.93 ? 41  PRO R O   1 
ATOM 23   C CB  . PRO A 1 97  ? 112.157 133.652 75.123  1.00 124.30 ? 41  PRO R CB  1 
ATOM 24   C CG  . PRO A 1 97  ? 111.533 134.920 74.644  1.00 125.07 ? 41  PRO R CG  1 
ATOM 25   C CD  . PRO A 1 97  ? 111.823 135.018 73.174  1.00 124.51 ? 41  PRO R CD  1 
ATOM 26   N N   . GLU A 1 98  ? 111.173 130.481 74.116  1.00 121.91 ? 42  GLU R N   1 
ATOM 27   C CA  . GLU A 1 98  ? 110.144 129.453 74.103  1.00 122.16 ? 42  GLU R CA  1 
ATOM 28   C C   . GLU A 1 98  ? 109.976 128.840 75.488  1.00 123.62 ? 42  GLU R C   1 
ATOM 29   O O   . GLU A 1 98  ? 110.866 128.910 76.340  1.00 122.90 ? 42  GLU R O   1 
ATOM 30   C CB  . GLU A 1 98  ? 110.479 128.357 73.085  1.00 122.36 ? 42  GLU R CB  1 
ATOM 31   N N   . SER A 1 99  ? 108.809 128.234 75.700  1.00 126.96 ? 43  SER R N   1 
ATOM 32   C CA  . SER A 1 99  ? 108.498 127.572 76.960  1.00 126.06 ? 43  SER R CA  1 
ATOM 33   C C   . SER A 1 99  ? 107.434 126.516 76.705  1.00 124.96 ? 43  SER R C   1 
ATOM 34   O O   . SER A 1 99  ? 106.773 126.513 75.663  1.00 124.83 ? 43  SER R O   1 
ATOM 35   C CB  . SER A 1 99  ? 108.023 128.572 78.020  1.00 126.22 ? 43  SER R CB  1 
ATOM 36   O OG  . SER A 1 99  ? 106.797 129.173 77.640  1.00 125.66 ? 43  SER R OG  1 
ATOM 37   N N   . LEU A 1 100 ? 107.278 125.615 77.673  1.00 129.17 ? 44  LEU R N   1 
ATOM 38   C CA  . LEU A 1 100 ? 106.293 124.547 77.596  1.00 130.18 ? 44  LEU R CA  1 
ATOM 39   C C   . LEU A 1 100 ? 105.515 124.466 78.902  1.00 130.81 ? 44  LEU R C   1 
ATOM 40   O O   . LEU A 1 100 ? 106.050 124.736 79.981  1.00 131.16 ? 44  LEU R O   1 
ATOM 41   C CB  . LEU A 1 100 ? 106.951 123.192 77.296  1.00 129.84 ? 44  LEU R CB  1 
ATOM 42   C CG  . LEU A 1 100 ? 107.753 123.093 75.998  1.00 129.64 ? 44  LEU R CG  1 
ATOM 43   C CD1 . LEU A 1 100 ? 108.542 121.793 75.949  1.00 128.05 ? 44  LEU R CD1 1 
ATOM 44   C CD2 . LEU A 1 100 ? 106.837 123.216 74.790  1.00 127.69 ? 44  LEU R CD2 1 
ATOM 45   N N   . GLU A 1 101 ? 104.238 124.089 78.790  1.00 125.86 ? 45  GLU R N   1 
ATOM 46   C CA  . GLU A 1 101 ? 103.396 123.961 79.976  1.00 125.07 ? 45  GLU R CA  1 
ATOM 47   C C   . GLU A 1 101 ? 103.771 122.740 80.805  1.00 124.65 ? 45  GLU R C   1 
ATOM 48   O O   . GLU A 1 101 ? 103.571 122.735 82.027  1.00 123.22 ? 45  GLU R O   1 
ATOM 49   C CB  . GLU A 1 101 ? 101.924 123.895 79.568  1.00 123.88 ? 45  GLU R CB  1 
ATOM 50   N N   . ILE A 1 102 ? 104.303 121.698 80.161  1.00 125.74 ? 46  ILE R N   1 
ATOM 51   C CA  . ILE A 1 102 ? 104.764 120.522 80.893  1.00 125.42 ? 46  ILE R CA  1 
ATOM 52   C C   . ILE A 1 102 ? 105.851 120.912 81.884  1.00 125.04 ? 46  ILE R C   1 
ATOM 53   O O   . ILE A 1 102 ? 105.872 120.439 83.028  1.00 125.01 ? 46  ILE R O   1 
ATOM 54   C CB  . ILE A 1 102 ? 105.255 119.441 79.911  1.00 126.11 ? 46  ILE R CB  1 
ATOM 55   C CG1 . ILE A 1 102 ? 104.115 118.991 78.995  1.00 126.08 ? 46  ILE R CG1 1 
ATOM 56   C CG2 . ILE A 1 102 ? 105.839 118.255 80.664  1.00 124.64 ? 46  ILE R CG2 1 
ATOM 57   C CD1 . ILE A 1 102 ? 104.585 118.306 77.730  1.00 124.70 ? 46  ILE R CD1 1 
ATOM 58   N N   . ASN A 1 103 ? 106.769 121.783 81.459  1.00 122.50 ? 47  ASN R N   1 
ATOM 59   C CA  . ASN A 1 103 ? 107.816 122.254 82.358  1.00 124.30 ? 47  ASN R CA  1 
ATOM 60   C C   . ASN A 1 103 ? 107.227 122.996 83.549  1.00 122.73 ? 47  ASN R C   1 
ATOM 61   O O   . ASN A 1 103 ? 107.662 122.795 84.687  1.00 122.43 ? 47  ASN R O   1 
ATOM 62   C CB  . ASN A 1 103 ? 108.797 123.149 81.599  1.00 120.70 ? 47  ASN R CB  1 
ATOM 63   N N   . LYS A 1 104 ? 106.232 123.854 83.310  1.00 111.88 ? 48  LYS R N   1 
ATOM 64   C CA  . LYS A 1 104 ? 105.617 124.594 84.409  1.00 111.01 ? 48  LYS R CA  1 
ATOM 65   C C   . LYS A 1 104 ? 104.933 123.655 85.395  1.00 111.08 ? 48  LYS R C   1 
ATOM 66   O O   . LYS A 1 104 ? 105.054 123.828 86.616  1.00 110.40 ? 48  LYS R O   1 
ATOM 67   C CB  . LYS A 1 104 ? 104.620 125.615 83.860  1.00 110.90 ? 48  LYS R CB  1 
ATOM 68   N N   . TYR A 1 105 ? 104.207 122.656 84.886  1.00 113.05 ? 49  TYR R N   1 
ATOM 69   C CA  . TYR A 1 105 ? 103.551 121.697 85.770  1.00 112.25 ? 49  TYR R CA  1 
ATOM 70   C C   . TYR A 1 105 ? 104.573 120.913 86.586  1.00 112.66 ? 49  TYR R C   1 
ATOM 71   O O   . TYR A 1 105 ? 104.397 120.715 87.796  1.00 113.23 ? 49  TYR R O   1 
ATOM 72   C CB  . TYR A 1 105 ? 102.670 120.749 84.957  1.00 112.03 ? 49  TYR R CB  1 
ATOM 73   N N   . PHE A 1 106 ? 105.652 120.468 85.940  1.00 111.42 ? 50  PHE R N   1 
ATOM 74   C CA  . PHE A 1 106 ? 106.716 119.770 86.654  1.00 112.43 ? 50  PHE R CA  1 
ATOM 75   C C   . PHE A 1 106 ? 107.295 120.647 87.757  1.00 112.92 ? 50  PHE R C   1 
ATOM 76   O O   . PHE A 1 106 ? 107.465 120.203 88.902  1.00 111.46 ? 50  PHE R O   1 
ATOM 77   C CB  . PHE A 1 106 ? 107.803 119.352 85.663  1.00 110.16 ? 50  PHE R CB  1 
ATOM 78   C CG  . PHE A 1 106 ? 109.005 118.721 86.301  1.00 113.35 ? 50  PHE R CG  1 
ATOM 79   C CD1 . PHE A 1 106 ? 108.933 117.451 86.847  1.00 115.74 ? 50  PHE R CD1 1 
ATOM 80   C CD2 . PHE A 1 106 ? 110.212 119.399 86.347  1.00 110.23 ? 50  PHE R CD2 1 
ATOM 81   C CE1 . PHE A 1 106 ? 110.043 116.869 87.431  1.00 113.07 ? 50  PHE R CE1 1 
ATOM 82   C CE2 . PHE A 1 106 ? 111.324 118.824 86.929  1.00 110.91 ? 50  PHE R CE2 1 
ATOM 83   C CZ  . PHE A 1 106 ? 111.240 117.557 87.472  1.00 110.59 ? 50  PHE R CZ  1 
ATOM 84   N N   . VAL A 1 107 ? 107.577 121.910 87.431  1.00 107.40 ? 51  VAL R N   1 
ATOM 85   C CA  . VAL A 1 107 ? 108.174 122.826 88.397  1.00 106.59 ? 51  VAL R CA  1 
ATOM 86   C C   . VAL A 1 107 ? 107.255 123.011 89.596  1.00 105.30 ? 51  VAL R C   1 
ATOM 87   O O   . VAL A 1 107 ? 107.697 122.951 90.748  1.00 105.16 ? 51  VAL R O   1 
ATOM 88   C CB  . VAL A 1 107 ? 108.506 124.172 87.725  1.00 105.93 ? 51  VAL R CB  1 
ATOM 89   C CG1 . VAL A 1 107 ? 108.919 125.195 88.761  1.00 103.58 ? 51  VAL R CG1 1 
ATOM 90   C CG2 . VAL A 1 107 ? 109.621 123.995 86.709  1.00 107.38 ? 51  VAL R CG2 1 
ATOM 91   N N   . VAL A 1 108 ? 105.961 123.223 89.348  1.00 102.70 ? 52  VAL R N   1 
ATOM 92   C CA  . VAL A 1 108 ? 105.061 123.520 90.459  1.00 102.02 ? 52  VAL R CA  1 
ATOM 93   C C   . VAL A 1 108 ? 104.832 122.283 91.323  1.00 103.07 ? 52  VAL R C   1 
ATOM 94   O O   . VAL A 1 108 ? 104.743 122.383 92.554  1.00 103.93 ? 52  VAL R O   1 
ATOM 95   C CB  . VAL A 1 108 ? 103.741 124.126 89.950  1.00 101.60 ? 52  VAL R CB  1 
ATOM 96   C CG1 . VAL A 1 108 ? 104.024 125.442 89.263  1.00 102.75 ? 52  VAL R CG1 1 
ATOM 97   C CG2 . VAL A 1 108 ? 103.004 123.177 89.026  1.00 102.73 ? 52  VAL R CG2 1 
ATOM 98   N N   . ILE A 1 109 ? 104.739 121.099 90.708  1.00 102.61 ? 53  ILE R N   1 
ATOM 99   C CA  . ILE A 1 109 ? 104.573 119.881 91.500  1.00 103.84 ? 53  ILE R CA  1 
ATOM 100  C C   . ILE A 1 109 ? 105.795 119.649 92.383  1.00 105.22 ? 53  ILE R C   1 
ATOM 101  O O   . ILE A 1 109 ? 105.674 119.343 93.579  1.00 105.51 ? 53  ILE R O   1 
ATOM 102  C CB  . ILE A 1 109 ? 104.291 118.672 90.588  1.00 102.89 ? 53  ILE R CB  1 
ATOM 103  C CG1 . ILE A 1 109 ? 102.910 118.799 89.941  1.00 103.88 ? 53  ILE R CG1 1 
ATOM 104  C CG2 . ILE A 1 109 ? 104.393 117.373 91.373  1.00 102.74 ? 53  ILE R CG2 1 
ATOM 105  C CD1 . ILE A 1 109 ? 102.798 118.129 88.588  1.00 104.02 ? 53  ILE R CD1 1 
ATOM 106  N N   . ILE A 1 110 ? 106.994 119.805 91.811  1.00 99.88  ? 54  ILE R N   1 
ATOM 107  C CA  . ILE A 1 110 ? 108.207 119.610 92.601  1.00 97.99  ? 54  ILE R CA  1 
ATOM 108  C C   . ILE A 1 110 ? 108.299 120.657 93.704  1.00 93.95  ? 54  ILE R C   1 
ATOM 109  O O   . ILE A 1 110 ? 108.730 120.362 94.825  1.00 94.38  ? 54  ILE R O   1 
ATOM 110  C CB  . ILE A 1 110 ? 109.450 119.622 91.692  1.00 97.50  ? 54  ILE R CB  1 
ATOM 111  C CG1 . ILE A 1 110 ? 109.375 118.481 90.676  1.00 96.52  ? 54  ILE R CG1 1 
ATOM 112  C CG2 . ILE A 1 110 ? 110.721 119.503 92.517  1.00 97.17  ? 54  ILE R CG2 1 
ATOM 113  C CD1 . ILE A 1 110 ? 109.543 117.107 91.285  1.00 96.76  ? 54  ILE R CD1 1 
ATOM 114  N N   . TYR A 1 111 ? 107.884 121.893 93.410  1.00 95.49  ? 55  TYR R N   1 
ATOM 115  C CA  . TYR A 1 111 ? 107.904 122.944 94.421  1.00 98.76  ? 55  TYR R CA  1 
ATOM 116  C C   . TYR A 1 111 ? 106.977 122.611 95.581  1.00 97.83  ? 55  TYR R C   1 
ATOM 117  O O   . TYR A 1 111 ? 107.342 122.795 96.747  1.00 99.89  ? 55  TYR R O   1 
ATOM 118  C CB  . TYR A 1 111 ? 107.508 124.279 93.793  1.00 99.12  ? 55  TYR R CB  1 
ATOM 119  C CG  . TYR A 1 111 ? 108.669 125.194 93.484  1.00 98.49  ? 55  TYR R CG  1 
ATOM 120  C CD1 . TYR A 1 111 ? 109.241 125.984 94.469  1.00 96.03  ? 55  TYR R CD1 1 
ATOM 121  C CD2 . TYR A 1 111 ? 109.193 125.266 92.203  1.00 100.26 ? 55  TYR R CD2 1 
ATOM 122  C CE1 . TYR A 1 111 ? 110.300 126.823 94.183  1.00 98.62  ? 55  TYR R CE1 1 
ATOM 123  C CE2 . TYR A 1 111 ? 110.251 126.099 91.909  1.00 101.43 ? 55  TYR R CE2 1 
ATOM 124  C CZ  . TYR A 1 111 ? 110.802 126.875 92.902  1.00 100.63 ? 55  TYR R CZ  1 
ATOM 125  O OH  . TYR A 1 111 ? 111.857 127.706 92.606  1.00 97.42  ? 55  TYR R OH  1 
ATOM 126  N N   . ALA A 1 112 ? 105.771 122.125 95.281  1.00 97.90  ? 56  ALA R N   1 
ATOM 127  C CA  . ALA A 1 112 ? 104.842 121.758 96.346  1.00 100.25 ? 56  ALA R CA  1 
ATOM 128  C C   . ALA A 1 112 ? 105.393 120.614 97.189  1.00 100.96 ? 56  ALA R C   1 
ATOM 129  O O   . ALA A 1 112 ? 105.302 120.639 98.426  1.00 100.30 ? 56  ALA R O   1 
ATOM 130  C CB  . ALA A 1 112 ? 103.484 121.385 95.753  1.00 100.20 ? 56  ALA R CB  1 
ATOM 131  N N   . LEU A 1 113 ? 105.973 119.601 96.536  1.00 101.60 ? 57  LEU R N   1 
ATOM 132  C CA  . LEU A 1 113 ? 106.539 118.481 97.283  1.00 100.37 ? 57  LEU R CA  1 
ATOM 133  C C   . LEU A 1 113 ? 107.679 118.940 98.185  1.00 101.63 ? 57  LEU R C   1 
ATOM 134  O O   . LEU A 1 113 ? 107.764 118.532 99.352  1.00 102.05 ? 57  LEU R O   1 
ATOM 135  C CB  . LEU A 1 113 ? 107.018 117.396 96.320  1.00 97.60  ? 57  LEU R CB  1 
ATOM 136  N N   . VAL A 1 114 ? 108.558 119.800 97.663  1.00 102.23 ? 58  VAL R N   1 
ATOM 137  C CA  . VAL A 1 114 ? 109.674 120.312 98.454  1.00 100.35 ? 58  VAL R CA  1 
ATOM 138  C C   . VAL A 1 114 ? 109.162 121.131 99.630  1.00 99.17  ? 58  VAL R C   1 
ATOM 139  O O   . VAL A 1 114 ? 109.672 121.022 100.752 1.00 97.66  ? 58  VAL R O   1 
ATOM 140  C CB  . VAL A 1 114 ? 110.623 121.135 97.563  1.00 96.06  ? 58  VAL R CB  1 
ATOM 141  C CG1 . VAL A 1 114 ? 111.521 122.013 98.411  1.00 94.27  ? 58  VAL R CG1 1 
ATOM 142  C CG2 . VAL A 1 114 ? 111.448 120.217 96.680  1.00 96.61  ? 58  VAL R CG2 1 
ATOM 143  N N   . PHE A 1 115 ? 108.153 121.971 99.390  1.00 100.13 ? 59  PHE R N   1 
ATOM 144  C CA  . PHE A 1 115 ? 107.571 122.771 100.461 1.00 99.95  ? 59  PHE R CA  1 
ATOM 145  C C   . PHE A 1 115 ? 107.045 121.885 101.581 1.00 101.00 ? 59  PHE R C   1 
ATOM 146  O O   . PHE A 1 115 ? 107.353 122.105 102.759 1.00 98.83  ? 59  PHE R O   1 
ATOM 147  C CB  . PHE A 1 115 ? 106.458 123.653 99.892  1.00 100.53 ? 59  PHE R CB  1 
ATOM 148  C CG  . PHE A 1 115 ? 105.551 124.243 100.932 1.00 101.62 ? 59  PHE R CG  1 
ATOM 149  C CD1 . PHE A 1 115 ? 106.063 124.990 101.979 1.00 102.16 ? 59  PHE R CD1 1 
ATOM 150  C CD2 . PHE A 1 115 ? 104.181 124.055 100.857 1.00 100.39 ? 59  PHE R CD2 1 
ATOM 151  C CE1 . PHE A 1 115 ? 105.226 125.536 102.933 1.00 102.03 ? 59  PHE R CE1 1 
ATOM 152  C CE2 . PHE A 1 115 ? 103.340 124.597 101.807 1.00 101.57 ? 59  PHE R CE2 1 
ATOM 153  C CZ  . PHE A 1 115 ? 103.863 125.339 102.847 1.00 102.82 ? 59  PHE R CZ  1 
ATOM 154  N N   . LEU A 1 116 ? 106.260 120.864 101.227 1.00 105.95 ? 60  LEU R N   1 
ATOM 155  C CA  . LEU A 1 116 ? 105.701 119.979 102.246 1.00 106.78 ? 60  LEU R CA  1 
ATOM 156  C C   . LEU A 1 116 ? 106.804 119.258 103.015 1.00 106.63 ? 60  LEU R C   1 
ATOM 157  O O   . LEU A 1 116 ? 106.781 119.199 104.255 1.00 107.38 ? 60  LEU R O   1 
ATOM 158  C CB  . LEU A 1 116 ? 104.747 118.974 101.600 1.00 104.25 ? 60  LEU R CB  1 
ATOM 159  N N   . LEU A 1 117 ? 107.788 118.711 102.294 1.00 103.71 ? 61  LEU R N   1 
ATOM 160  C CA  . LEU A 1 117 ? 108.843 117.942 102.948 1.00 102.97 ? 61  LEU R CA  1 
ATOM 161  C C   . LEU A 1 117 ? 109.659 118.814 103.894 1.00 105.50 ? 61  LEU R C   1 
ATOM 162  O O   . LEU A 1 117 ? 109.939 118.419 105.033 1.00 105.41 ? 61  LEU R O   1 
ATOM 163  C CB  . LEU A 1 117 ? 109.745 117.294 101.899 1.00 99.90  ? 61  LEU R CB  1 
ATOM 164  C CG  . LEU A 1 117 ? 109.183 116.052 101.207 1.00 103.49 ? 61  LEU R CG  1 
ATOM 165  C CD1 . LEU A 1 117 ? 110.074 115.635 100.049 1.00 103.43 ? 61  LEU R CD1 1 
ATOM 166  C CD2 . LEU A 1 117 ? 109.023 114.916 102.202 1.00 103.73 ? 61  LEU R CD2 1 
ATOM 167  N N   . SER A 1 118 ? 110.050 120.008 103.441 1.00 103.45 ? 62  SER R N   1 
ATOM 168  C CA  . SER A 1 118 ? 110.838 120.899 104.286 1.00 101.52 ? 62  SER R CA  1 
ATOM 169  C C   . SER A 1 118 ? 110.039 121.346 105.501 1.00 101.92 ? 62  SER R C   1 
ATOM 170  O O   . SER A 1 118 ? 110.561 121.368 106.626 1.00 101.28 ? 62  SER R O   1 
ATOM 171  C CB  . SER A 1 118 ? 111.313 122.105 103.477 1.00 100.18 ? 62  SER R CB  1 
ATOM 172  O OG  . SER A 1 118 ? 112.403 121.761 102.642 1.00 101.96 ? 62  SER R OG  1 
ATOM 173  N N   . LEU A 1 119 ? 108.770 121.713 105.295 1.00 98.04  ? 63  LEU R N   1 
ATOM 174  C CA  . LEU A 1 119 ? 107.919 122.099 106.413 1.00 96.74  ? 63  LEU R CA  1 
ATOM 175  C C   . LEU A 1 119 ? 107.901 121.011 107.476 1.00 96.93  ? 63  LEU R C   1 
ATOM 176  O O   . LEU A 1 119 ? 108.195 121.267 108.650 1.00 93.39  ? 63  LEU R O   1 
ATOM 177  C CB  . LEU A 1 119 ? 106.505 122.388 105.906 1.00 96.69  ? 63  LEU R CB  1 
ATOM 178  C CG  . LEU A 1 119 ? 105.413 122.635 106.948 1.00 99.22  ? 63  LEU R CG  1 
ATOM 179  C CD1 . LEU A 1 119 ? 105.700 123.899 107.740 1.00 99.23  ? 63  LEU R CD1 1 
ATOM 180  C CD2 . LEU A 1 119 ? 104.045 122.708 106.284 1.00 95.47  ? 63  LEU R CD2 1 
ATOM 181  N N   . LEU A 1 120 ? 107.605 119.774 107.066 1.00 101.29 ? 64  LEU R N   1 
ATOM 182  C CA  . LEU A 1 120 ? 107.524 118.678 108.028 1.00 101.19 ? 64  LEU R CA  1 
ATOM 183  C C   . LEU A 1 120 ? 108.863 118.448 108.723 1.00 102.17 ? 64  LEU R C   1 
ATOM 184  O O   . LEU A 1 120 ? 108.924 118.330 109.955 1.00 101.42 ? 64  LEU R O   1 
ATOM 185  C CB  . LEU A 1 120 ? 107.049 117.405 107.328 1.00 99.77  ? 64  LEU R CB  1 
ATOM 186  C CG  . LEU A 1 120 ? 106.792 116.187 108.217 1.00 101.19 ? 64  LEU R CG  1 
ATOM 187  C CD1 . LEU A 1 120 ? 105.620 116.440 109.151 1.00 99.34  ? 64  LEU R CD1 1 
ATOM 188  C CD2 . LEU A 1 120 ? 106.538 114.954 107.363 1.00 102.91 ? 64  LEU R CD2 1 
ATOM 189  N N   . GLY A 1 121 ? 109.950 118.392 107.948 1.00 99.76  ? 65  GLY R N   1 
ATOM 190  C CA  . GLY A 1 121 ? 111.243 118.063 108.528 1.00 97.83  ? 65  GLY R CA  1 
ATOM 191  C C   . GLY A 1 121 ? 111.707 119.081 109.551 1.00 97.71  ? 65  GLY R C   1 
ATOM 192  O O   . GLY A 1 121 ? 112.049 118.730 110.687 1.00 98.79  ? 65  GLY R O   1 
ATOM 193  N N   . ASN A 1 122 ? 111.712 120.363 109.194 1.00 93.98  ? 66  ASN R N   1 
ATOM 194  C CA  . ASN A 1 122 ? 112.152 121.414 110.148 1.00 92.75  ? 66  ASN R CA  1 
ATOM 195  C C   . ASN A 1 122 ? 111.110 121.586 111.275 1.00 93.69  ? 66  ASN R C   1 
ATOM 196  O O   . ASN A 1 122 ? 111.473 122.114 112.326 1.00 89.25  ? 66  ASN R O   1 
ATOM 197  C CB  . ASN A 1 122 ? 112.590 122.668 109.400 1.00 92.01  ? 66  ASN R CB  1 
ATOM 198  C CG  . ASN A 1 122 ? 113.141 122.372 108.022 1.00 92.82  ? 66  ASN R CG  1 
ATOM 199  O OD1 . ASN A 1 122 ? 114.151 121.694 107.885 1.00 95.47  ? 66  ASN R OD1 1 
ATOM 200  N ND2 . ASN A 1 122 ? 112.491 122.879 106.990 1.00 91.81  ? 66  ASN R ND2 1 
ATOM 201  N N   . SER A 1 123 ? 109.845 121.213 111.071 1.00 99.54  ? 67  SER R N   1 
ATOM 202  C CA  . SER A 1 123 ? 108.919 121.197 112.196 1.00 99.32  ? 67  SER R CA  1 
ATOM 203  C C   . SER A 1 123 ? 109.338 120.159 113.227 1.00 101.16 ? 67  SER R C   1 
ATOM 204  O O   . SER A 1 123 ? 109.383 120.450 114.431 1.00 105.06 ? 67  SER R O   1 
ATOM 205  C CB  . SER A 1 123 ? 107.499 120.928 111.702 1.00 97.88  ? 67  SER R CB  1 
ATOM 206  O OG  . SER A 1 123 ? 107.042 121.984 110.875 1.00 97.74  ? 67  SER R OG  1 
ATOM 207  N N   . LEU A 1 124 ? 109.688 118.952 112.771 1.00 95.38  ? 68  LEU R N   1 
ATOM 208  C CA  . LEU A 1 124 ? 110.152 117.936 113.714 1.00 93.56  ? 68  LEU R CA  1 
ATOM 209  C C   . LEU A 1 124 ? 111.449 118.363 114.391 1.00 92.04  ? 68  LEU R C   1 
ATOM 210  O O   . LEU A 1 124 ? 111.630 118.131 115.594 1.00 89.46  ? 68  LEU R O   1 
ATOM 211  C CB  . LEU A 1 124 ? 110.340 116.585 113.020 1.00 96.18  ? 68  LEU R CB  1 
ATOM 212  C CG  . LEU A 1 124 ? 109.355 116.112 111.953 1.00 96.61  ? 68  LEU R CG  1 
ATOM 213  C CD1 . LEU A 1 124 ? 109.849 114.831 111.298 1.00 93.61  ? 68  LEU R CD1 1 
ATOM 214  C CD2 . LEU A 1 124 ? 107.972 115.912 112.549 1.00 98.34  ? 68  LEU R CD2 1 
ATOM 215  N N   . VAL A 1 125 ? 112.359 118.991 113.642 1.00 95.16  ? 69  VAL R N   1 
ATOM 216  C CA  . VAL A 1 125 ? 113.642 119.388 114.225 1.00 94.50  ? 69  VAL R CA  1 
ATOM 217  C C   . VAL A 1 125 ? 113.433 120.393 115.356 1.00 95.68  ? 69  VAL R C   1 
ATOM 218  O O   . VAL A 1 125 ? 113.954 120.219 116.467 1.00 97.37  ? 69  VAL R O   1 
ATOM 219  C CB  . VAL A 1 125 ? 114.585 119.944 113.144 1.00 96.59  ? 69  VAL R CB  1 
ATOM 220  C CG1 . VAL A 1 125 ? 115.888 120.402 113.776 1.00 91.40  ? 69  VAL R CG1 1 
ATOM 221  C CG2 . VAL A 1 125 ? 114.864 118.887 112.092 1.00 98.43  ? 69  VAL R CG2 1 
ATOM 222  N N   . MET A 1 126 ? 112.664 121.457 115.095 1.00 97.21  ? 70  MET R N   1 
ATOM 223  C CA  . MET A 1 126 ? 112.433 122.453 116.141 1.00 94.40  ? 70  MET R CA  1 
ATOM 224  C C   . MET A 1 126 ? 111.642 121.873 117.306 1.00 94.58  ? 70  MET R C   1 
ATOM 225  O O   . MET A 1 126 ? 111.913 122.207 118.465 1.00 91.37  ? 70  MET R O   1 
ATOM 226  C CB  . MET A 1 126 ? 111.736 123.700 115.590 1.00 92.37  ? 70  MET R CB  1 
ATOM 227  C CG  . MET A 1 126 ? 112.118 124.095 114.184 1.00 92.83  ? 70  MET R CG  1 
ATOM 228  S SD  . MET A 1 126 ? 113.176 125.553 114.141 1.00 97.18  ? 70  MET R SD  1 
ATOM 229  C CE  . MET A 1 126 ? 111.952 126.859 114.141 1.00 93.77  ? 70  MET R CE  1 
ATOM 230  N N   . LEU A 1 127 ? 110.659 121.009 117.031 1.00 106.53 ? 71  LEU R N   1 
ATOM 231  C CA  . LEU A 1 127 ? 109.901 120.405 118.124 1.00 106.46 ? 71  LEU R CA  1 
ATOM 232  C C   . LEU A 1 127 ? 110.812 119.591 119.036 1.00 107.22 ? 71  LEU R C   1 
ATOM 233  O O   . LEU A 1 127 ? 110.766 119.729 120.266 1.00 107.74 ? 71  LEU R O   1 
ATOM 234  C CB  . LEU A 1 127 ? 108.777 119.530 117.566 1.00 106.26 ? 71  LEU R CB  1 
ATOM 235  C CG  . LEU A 1 127 ? 108.231 118.446 118.501 1.00 107.84 ? 71  LEU R CG  1 
ATOM 236  C CD1 . LEU A 1 127 ? 107.494 119.059 119.685 1.00 107.42 ? 71  LEU R CD1 1 
ATOM 237  C CD2 . LEU A 1 127 ? 107.331 117.480 117.745 1.00 108.77 ? 71  LEU R CD2 1 
ATOM 238  N N   . VAL A 1 128 ? 111.668 118.754 118.445 1.00 103.47 ? 72  VAL R N   1 
ATOM 239  C CA  . VAL A 1 128 ? 112.556 117.913 119.242 1.00 102.39 ? 72  VAL R CA  1 
ATOM 240  C C   . VAL A 1 128 ? 113.533 118.771 120.033 1.00 103.34 ? 72  VAL R C   1 
ATOM 241  O O   . VAL A 1 128 ? 113.805 118.502 121.210 1.00 102.13 ? 72  VAL R O   1 
ATOM 242  C CB  . VAL A 1 128 ? 113.290 116.903 118.341 1.00 102.56 ? 72  VAL R CB  1 
ATOM 243  C CG1 . VAL A 1 128 ? 114.489 116.317 119.066 1.00 101.63 ? 72  VAL R CG1 1 
ATOM 244  C CG2 . VAL A 1 128 ? 112.343 115.804 117.899 1.00 104.75 ? 72  VAL R CG2 1 
ATOM 245  N N   . ILE A 1 129 ? 114.073 119.820 119.408 1.00 107.35 ? 73  ILE R N   1 
ATOM 246  C CA  . ILE A 1 129 ? 115.056 120.655 120.093 1.00 104.28 ? 73  ILE R CA  1 
ATOM 247  C C   . ILE A 1 129 ? 114.413 121.402 121.257 1.00 104.41 ? 73  ILE R C   1 
ATOM 248  O O   . ILE A 1 129 ? 114.955 121.436 122.368 1.00 105.58 ? 73  ILE R O   1 
ATOM 249  C CB  . ILE A 1 129 ? 115.725 121.623 119.103 1.00 100.45 ? 73  ILE R CB  1 
ATOM 250  C CG1 . ILE A 1 129 ? 116.741 120.876 118.242 1.00 100.26 ? 73  ILE R CG1 1 
ATOM 251  C CG2 . ILE A 1 129 ? 116.408 122.756 119.846 1.00 99.47  ? 73  ILE R CG2 1 
ATOM 252  C CD1 . ILE A 1 129 ? 117.491 121.761 117.281 1.00 103.60 ? 73  ILE R CD1 1 
ATOM 253  N N   . LEU A 1 130 ? 113.244 122.001 121.029 1.00 112.02 ? 74  LEU R N   1 
ATOM 254  C CA  . LEU A 1 130 ? 112.664 122.922 121.996 1.00 113.05 ? 74  LEU R CA  1 
ATOM 255  C C   . LEU A 1 130 ? 111.732 122.262 123.003 1.00 114.49 ? 74  LEU R C   1 
ATOM 256  O O   . LEU A 1 130 ? 111.280 122.943 123.929 1.00 117.80 ? 74  LEU R O   1 
ATOM 257  C CB  . LEU A 1 130 ? 111.903 124.036 121.269 1.00 113.81 ? 74  LEU R CB  1 
ATOM 258  C CG  . LEU A 1 130 ? 112.750 125.183 120.716 1.00 114.55 ? 74  LEU R CG  1 
ATOM 259  C CD1 . LEU A 1 130 ? 111.862 126.263 120.122 1.00 112.80 ? 74  LEU R CD1 1 
ATOM 260  C CD2 . LEU A 1 130 ? 113.647 125.759 121.802 1.00 113.18 ? 74  LEU R CD2 1 
ATOM 261  N N   . TYR A 1 131 ? 111.420 120.971 122.857 1.00 118.92 ? 75  TYR R N   1 
ATOM 262  C CA  . TYR A 1 131 ? 110.545 120.336 123.839 1.00 119.03 ? 75  TYR R CA  1 
ATOM 263  C C   . TYR A 1 131 ? 111.226 120.224 125.200 1.00 121.02 ? 75  TYR R C   1 
ATOM 264  O O   . TYR A 1 131 ? 110.640 120.582 126.228 1.00 121.92 ? 75  TYR R O   1 
ATOM 265  C CB  . TYR A 1 131 ? 110.098 118.961 123.346 1.00 119.68 ? 75  TYR R CB  1 
ATOM 266  C CG  . TYR A 1 131 ? 108.808 118.481 123.980 1.00 122.55 ? 75  TYR R CG  1 
ATOM 267  C CD1 . TYR A 1 131 ? 108.762 118.108 125.318 1.00 121.80 ? 75  TYR R CD1 1 
ATOM 268  C CD2 . TYR A 1 131 ? 107.636 118.399 123.239 1.00 123.35 ? 75  TYR R CD2 1 
ATOM 269  C CE1 . TYR A 1 131 ? 107.587 117.669 125.899 1.00 120.76 ? 75  TYR R CE1 1 
ATOM 270  C CE2 . TYR A 1 131 ? 106.457 117.960 123.812 1.00 123.32 ? 75  TYR R CE2 1 
ATOM 271  C CZ  . TYR A 1 131 ? 106.438 117.597 125.142 1.00 121.84 ? 75  TYR R CZ  1 
ATOM 272  O OH  . TYR A 1 131 ? 105.267 117.161 125.716 1.00 120.82 ? 75  TYR R OH  1 
ATOM 273  N N   . SER A 1 132 ? 112.462 119.729 125.230 1.00 128.48 ? 76  SER R N   1 
ATOM 274  C CA  . SER A 1 132 ? 113.181 119.501 126.477 1.00 130.11 ? 76  SER R CA  1 
ATOM 275  C C   . SER A 1 132 ? 114.523 120.214 126.433 1.00 130.70 ? 76  SER R C   1 
ATOM 276  O O   . SER A 1 132 ? 115.255 120.109 125.444 1.00 130.35 ? 76  SER R O   1 
ATOM 277  C CB  . SER A 1 132 ? 113.384 118.003 126.734 1.00 127.29 ? 76  SER R CB  1 
ATOM 278  O OG  . SER A 1 132 ? 113.679 117.313 125.533 1.00 128.82 ? 76  SER R OG  1 
ATOM 279  N N   . ARG A 1 133 ? 114.845 120.932 127.511 1.00 125.04 ? 77  ARG R N   1 
ATOM 280  C CA  . ARG A 1 133 ? 116.081 121.694 127.617 1.00 123.35 ? 77  ARG R CA  1 
ATOM 281  C C   . ARG A 1 133 ? 117.205 120.912 128.289 1.00 120.23 ? 77  ARG R C   1 
ATOM 282  O O   . ARG A 1 133 ? 118.128 121.524 128.839 1.00 116.81 ? 77  ARG R O   1 
ATOM 283  C CB  . ARG A 1 133 ? 115.832 122.998 128.378 1.00 121.85 ? 77  ARG R CB  1 
ATOM 284  C CG  . ARG A 1 133 ? 115.125 124.073 127.570 1.00 121.44 ? 77  ARG R CG  1 
ATOM 285  C CD  . ARG A 1 133 ? 114.940 125.339 128.395 1.00 122.74 ? 77  ARG R CD  1 
ATOM 286  N NE  . ARG A 1 133 ? 115.159 126.548 127.609 1.00 123.90 ? 77  ARG R NE  1 
ATOM 287  C CZ  . ARG A 1 133 ? 114.434 127.653 127.719 1.00 121.44 ? 77  ARG R CZ  1 
ATOM 288  N NH1 . ARG A 1 133 ? 113.425 127.735 128.571 1.00 121.43 ? 77  ARG R NH1 1 
ATOM 289  N NH2 . ARG A 1 133 ? 114.728 128.701 126.955 1.00 119.00 ? 77  ARG R NH2 1 
ATOM 290  N N   . VAL A 1 134 ? 117.153 119.583 128.259 1.00 121.41 ? 78  VAL R N   1 
ATOM 291  C CA  . VAL A 1 134 ? 118.169 118.758 128.906 1.00 122.86 ? 78  VAL R CA  1 
ATOM 292  C C   . VAL A 1 134 ? 119.367 118.651 127.967 1.00 125.45 ? 78  VAL R C   1 
ATOM 293  O O   . VAL A 1 134 ? 119.277 118.044 126.897 1.00 128.29 ? 78  VAL R O   1 
ATOM 294  C CB  . VAL A 1 134 ? 117.623 117.372 129.266 1.00 122.47 ? 78  VAL R CB  1 
ATOM 295  C CG1 . VAL A 1 134 ? 118.755 116.452 129.702 1.00 120.49 ? 78  VAL R CG1 1 
ATOM 296  C CG2 . VAL A 1 134 ? 116.565 117.481 130.354 1.00 121.55 ? 78  VAL R CG2 1 
ATOM 297  N N   . GLY A 1 135 ? 120.492 119.237 128.369 1.00 120.29 ? 79  GLY R N   1 
ATOM 298  C CA  . GLY A 1 135 ? 121.694 119.199 127.560 1.00 119.74 ? 79  GLY R CA  1 
ATOM 299  C C   . GLY A 1 135 ? 121.605 120.033 126.298 1.00 119.25 ? 79  GLY R C   1 
ATOM 300  O O   . GLY A 1 135 ? 121.609 119.494 125.187 1.00 118.73 ? 79  GLY R O   1 
ATOM 301  N N   . ARG A 1 136 ? 121.527 121.355 126.456 1.00 107.26 ? 80  ARG R N   1 
ATOM 302  C CA  . ARG A 1 136 ? 121.427 122.272 125.321 1.00 106.54 ? 80  ARG R CA  1 
ATOM 303  C C   . ARG A 1 136 ? 122.830 122.559 124.792 1.00 107.05 ? 80  ARG R C   1 
ATOM 304  O O   . ARG A 1 136 ? 123.447 123.588 125.078 1.00 110.45 ? 80  ARG R O   1 
ATOM 305  C CB  . ARG A 1 136 ? 120.707 123.552 125.725 1.00 110.00 ? 80  ARG R CB  1 
ATOM 306  C CG  . ARG A 1 136 ? 119.230 123.366 126.016 1.00 109.20 ? 80  ARG R CG  1 
ATOM 307  C CD  . ARG A 1 136 ? 118.414 124.491 125.405 1.00 107.85 ? 80  ARG R CD  1 
ATOM 308  N NE  . ARG A 1 136 ? 118.795 124.734 124.019 1.00 107.76 ? 80  ARG R NE  1 
ATOM 309  C CZ  . ARG A 1 136 ? 118.140 124.262 122.968 1.00 106.18 ? 80  ARG R CZ  1 
ATOM 310  N NH1 . ARG A 1 136 ? 117.058 123.514 123.107 1.00 107.06 ? 80  ARG R NH1 1 
ATOM 311  N NH2 . ARG A 1 136 ? 118.582 124.547 121.747 1.00 105.13 ? 80  ARG R NH2 1 
ATOM 312  N N   . SER A 1 137 ? 123.338 121.620 123.999 1.00 94.07  ? 81  SER R N   1 
ATOM 313  C CA  . SER A 1 137 ? 124.665 121.747 123.421 1.00 94.15  ? 81  SER R CA  1 
ATOM 314  C C   . SER A 1 137 ? 124.656 122.745 122.263 1.00 95.10  ? 81  SER R C   1 
ATOM 315  O O   . SER A 1 137 ? 123.606 123.157 121.764 1.00 96.08  ? 81  SER R O   1 
ATOM 316  C CB  . SER A 1 137 ? 125.178 120.387 122.951 1.00 94.47  ? 81  SER R CB  1 
ATOM 317  O OG  . SER A 1 137 ? 125.431 119.532 124.051 1.00 95.07  ? 81  SER R OG  1 
ATOM 318  N N   . VAL A 1 138 ? 125.861 123.133 121.838 1.00 85.47  ? 82  VAL R N   1 
ATOM 319  C CA  . VAL A 1 138 ? 126.010 124.103 120.756 1.00 84.13  ? 82  VAL R CA  1 
ATOM 320  C C   . VAL A 1 138 ? 125.459 123.551 119.448 1.00 81.68  ? 82  VAL R C   1 
ATOM 321  O O   . VAL A 1 138 ? 124.905 124.300 118.627 1.00 85.38  ? 82  VAL R O   1 
ATOM 322  C CB  . VAL A 1 138 ? 127.490 124.513 120.625 1.00 85.52  ? 82  VAL R CB  1 
ATOM 323  C CG1 . VAL A 1 138 ? 127.936 125.269 121.865 1.00 84.02  ? 82  VAL R CG1 1 
ATOM 324  C CG2 . VAL A 1 138 ? 128.370 123.294 120.410 1.00 88.13  ? 82  VAL R CG2 1 
ATOM 325  N N   . THR A 1 139 ? 125.606 122.243 119.228 1.00 79.12  ? 83  THR R N   1 
ATOM 326  C CA  . THR A 1 139 ? 125.069 121.626 118.021 1.00 82.75  ? 83  THR R CA  1 
ATOM 327  C C   . THR A 1 139 ? 123.562 121.816 117.937 1.00 84.95  ? 83  THR R C   1 
ATOM 328  O O   . THR A 1 139 ? 123.014 122.022 116.849 1.00 82.66  ? 83  THR R O   1 
ATOM 329  C CB  . THR A 1 139 ? 125.427 120.141 117.991 1.00 80.46  ? 83  THR R CB  1 
ATOM 330  O OG1 . THR A 1 139 ? 126.821 119.981 118.276 1.00 82.33  ? 83  THR R OG1 1 
ATOM 331  C CG2 . THR A 1 139 ? 125.127 119.551 116.625 1.00 80.49  ? 83  THR R CG2 1 
ATOM 332  N N   . ASP A 1 140 ? 122.875 121.760 119.080 1.00 92.00  ? 84  ASP R N   1 
ATOM 333  C CA  . ASP A 1 140 ? 121.438 122.006 119.088 1.00 89.98  ? 84  ASP R CA  1 
ATOM 334  C C   . ASP A 1 140 ? 121.120 123.425 118.634 1.00 86.70  ? 84  ASP R C   1 
ATOM 335  O O   . ASP A 1 140 ? 120.165 123.642 117.883 1.00 87.75  ? 84  ASP R O   1 
ATOM 336  C CB  . ASP A 1 140 ? 120.868 121.745 120.481 1.00 92.73  ? 84  ASP R CB  1 
ATOM 337  C CG  . ASP A 1 140 ? 121.074 120.315 120.935 1.00 92.38  ? 84  ASP R CG  1 
ATOM 338  O OD1 . ASP A 1 140 ? 121.571 119.501 120.129 1.00 88.86  ? 84  ASP R OD1 1 
ATOM 339  O OD2 . ASP A 1 140 ? 120.738 120.003 122.097 1.00 94.07  ? 84  ASP R OD2 1 
ATOM 340  N N   . VAL A 1 141 ? 121.911 124.404 119.078 1.00 77.77  ? 85  VAL R N   1 
ATOM 341  C CA  . VAL A 1 141 ? 121.695 125.788 118.660 1.00 79.53  ? 85  VAL R CA  1 
ATOM 342  C C   . VAL A 1 141 ? 121.876 125.922 117.152 1.00 76.33  ? 85  VAL R C   1 
ATOM 343  O O   . VAL A 1 141 ? 121.049 126.530 116.455 1.00 73.83  ? 85  VAL R O   1 
ATOM 344  C CB  . VAL A 1 141 ? 122.640 126.730 119.426 1.00 77.64  ? 85  VAL R CB  1 
ATOM 345  C CG1 . VAL A 1 141 ? 122.657 128.107 118.786 1.00 74.74  ? 85  VAL R CG1 1 
ATOM 346  C CG2 . VAL A 1 141 ? 122.233 126.817 120.887 1.00 78.90  ? 85  VAL R CG2 1 
ATOM 347  N N   . TYR A 1 142 ? 122.965 125.352 116.626 1.00 70.07  ? 86  TYR R N   1 
ATOM 348  C CA  . TYR A 1 142 ? 123.216 125.433 115.190 1.00 60.08  ? 86  TYR R CA  1 
ATOM 349  C C   . TYR A 1 142 ? 122.099 124.769 114.396 1.00 64.19  ? 86  TYR R C   1 
ATOM 350  O O   . TYR A 1 142 ? 121.640 125.307 113.381 1.00 71.00  ? 86  TYR R O   1 
ATOM 351  C CB  . TYR A 1 142 ? 124.559 124.790 114.852 1.00 61.82  ? 86  TYR R CB  1 
ATOM 352  C CG  . TYR A 1 142 ? 125.751 125.692 115.054 1.00 62.24  ? 86  TYR R CG  1 
ATOM 353  C CD1 . TYR A 1 142 ? 125.921 126.831 114.281 1.00 64.45  ? 86  TYR R CD1 1 
ATOM 354  C CD2 . TYR A 1 142 ? 126.716 125.396 116.005 1.00 63.28  ? 86  TYR R CD2 1 
ATOM 355  C CE1 . TYR A 1 142 ? 127.012 127.655 114.456 1.00 65.07  ? 86  TYR R CE1 1 
ATOM 356  C CE2 . TYR A 1 142 ? 127.811 126.214 116.186 1.00 64.00  ? 86  TYR R CE2 1 
ATOM 357  C CZ  . TYR A 1 142 ? 127.954 127.343 115.410 1.00 64.84  ? 86  TYR R CZ  1 
ATOM 358  O OH  . TYR A 1 142 ? 129.043 128.163 115.587 1.00 67.96  ? 86  TYR R OH  1 
ATOM 359  N N   . LEU A 1 143 ? 121.645 123.602 114.851 1.00 70.36  ? 87  LEU R N   1 
ATOM 360  C CA  . LEU A 1 143 ? 120.599 122.875 114.142 1.00 70.85  ? 87  LEU R CA  1 
ATOM 361  C C   . LEU A 1 143 ? 119.268 123.611 114.207 1.00 73.31  ? 87  LEU R C   1 
ATOM 362  O O   . LEU A 1 143 ? 118.517 123.627 113.227 1.00 78.06  ? 87  LEU R O   1 
ATOM 363  C CB  . LEU A 1 143 ? 120.479 121.468 114.719 1.00 72.56  ? 87  LEU R CB  1 
ATOM 364  C CG  . LEU A 1 143 ? 121.250 120.380 113.974 1.00 73.51  ? 87  LEU R CG  1 
ATOM 365  C CD1 . LEU A 1 143 ? 122.745 120.601 114.058 1.00 74.80  ? 87  LEU R CD1 1 
ATOM 366  C CD2 . LEU A 1 143 ? 120.908 119.049 114.584 1.00 75.99  ? 87  LEU R CD2 1 
ATOM 367  N N   . LEU A 1 144 ? 118.959 124.230 115.349 1.00 74.33  ? 88  LEU R N   1 
ATOM 368  C CA  . LEU A 1 144 ? 117.744 125.030 115.459 1.00 72.57  ? 88  LEU R CA  1 
ATOM 369  C C   . LEU A 1 144 ? 117.772 126.205 114.491 1.00 69.98  ? 88  LEU R C   1 
ATOM 370  O O   . LEU A 1 144 ? 116.785 126.477 113.799 1.00 68.66  ? 88  LEU R O   1 
ATOM 371  C CB  . LEU A 1 144 ? 117.573 125.522 116.896 1.00 74.94  ? 88  LEU R CB  1 
ATOM 372  C CG  . LEU A 1 144 ? 116.267 126.243 117.232 1.00 73.39  ? 88  LEU R CG  1 
ATOM 373  C CD1 . LEU A 1 144 ? 115.154 125.256 117.534 1.00 70.97  ? 88  LEU R CD1 1 
ATOM 374  C CD2 . LEU A 1 144 ? 116.480 127.186 118.403 1.00 74.07  ? 88  LEU R CD2 1 
ATOM 375  N N   . ASN A 1 145 ? 118.902 126.914 114.427 1.00 62.91  ? 89  ASN R N   1 
ATOM 376  C CA  . ASN A 1 145 ? 119.002 128.043 113.506 1.00 56.87  ? 89  ASN R CA  1 
ATOM 377  C C   . ASN A 1 145 ? 118.877 127.588 112.055 1.00 61.62  ? 89  ASN R C   1 
ATOM 378  O O   . ASN A 1 145 ? 118.181 128.223 111.250 1.00 70.43  ? 89  ASN R O   1 
ATOM 379  C CB  . ASN A 1 145 ? 120.318 128.788 113.727 1.00 62.90  ? 89  ASN R CB  1 
ATOM 380  C CG  . ASN A 1 145 ? 120.384 129.474 115.078 1.00 66.36  ? 89  ASN R CG  1 
ATOM 381  O OD1 . ASN A 1 145 ? 120.518 130.694 115.158 1.00 71.28  ? 89  ASN R OD1 1 
ATOM 382  N ND2 . ASN A 1 145 ? 120.305 128.694 116.148 1.00 65.48  ? 89  ASN R ND2 1 
ATOM 383  N N   . LEU A 1 146 ? 119.539 126.482 111.706 1.00 64.79  ? 90  LEU R N   1 
ATOM 384  C CA  . LEU A 1 146 ? 119.467 125.971 110.342 1.00 65.94  ? 90  LEU R CA  1 
ATOM 385  C C   . LEU A 1 146 ? 118.046 125.550 109.981 1.00 70.10  ? 90  LEU R C   1 
ATOM 386  O O   . LEU A 1 146 ? 117.563 125.836 108.876 1.00 74.42  ? 90  LEU R O   1 
ATOM 387  C CB  . LEU A 1 146 ? 120.439 124.803 110.183 1.00 60.21  ? 90  LEU R CB  1 
ATOM 388  C CG  . LEU A 1 146 ? 120.716 124.282 108.776 1.00 67.40  ? 90  LEU R CG  1 
ATOM 389  C CD1 . LEU A 1 146 ? 121.500 125.307 107.982 1.00 69.09  ? 90  LEU R CD1 1 
ATOM 390  C CD2 . LEU A 1 146 ? 121.476 122.971 108.852 1.00 69.73  ? 90  LEU R CD2 1 
ATOM 391  N N   . ALA A 1 147 ? 117.358 124.873 110.904 1.00 67.39  ? 91  ALA R N   1 
ATOM 392  C CA  . ALA A 1 147 ? 115.983 124.461 110.655 1.00 66.06  ? 91  ALA R CA  1 
ATOM 393  C C   . ALA A 1 147 ? 115.062 125.666 110.520 1.00 70.82  ? 91  ALA R C   1 
ATOM 394  O O   . ALA A 1 147 ? 114.143 125.655 109.698 1.00 75.25  ? 91  ALA R O   1 
ATOM 395  C CB  . ALA A 1 147 ? 115.499 123.535 111.769 1.00 69.02  ? 91  ALA R CB  1 
ATOM 396  N N   . LEU A 1 148 ? 115.286 126.710 111.320 1.00 69.59  ? 92  LEU R N   1 
ATOM 397  C CA  . LEU A 1 148 ? 114.488 127.926 111.190 1.00 68.72  ? 92  LEU R CA  1 
ATOM 398  C C   . LEU A 1 148 ? 114.676 128.558 109.816 1.00 73.61  ? 92  LEU R C   1 
ATOM 399  O O   . LEU A 1 148 ? 113.703 128.965 109.164 1.00 79.78  ? 92  LEU R O   1 
ATOM 400  C CB  . LEU A 1 148 ? 114.866 128.914 112.293 1.00 72.40  ? 92  LEU R CB  1 
ATOM 401  C CG  . LEU A 1 148 ? 114.332 130.341 112.167 1.00 68.40  ? 92  LEU R CG  1 
ATOM 402  C CD1 . LEU A 1 148 ? 112.818 130.353 112.278 1.00 74.22  ? 92  LEU R CD1 1 
ATOM 403  C CD2 . LEU A 1 148 ? 114.961 131.242 113.217 1.00 67.55  ? 92  LEU R CD2 1 
ATOM 404  N N   . ALA A 1 149 ? 115.929 128.648 109.361 1.00 71.23  ? 93  ALA R N   1 
ATOM 405  C CA  . ALA A 1 149 ? 116.198 129.226 108.046 1.00 65.98  ? 93  ALA R CA  1 
ATOM 406  C C   . ALA A 1 149 ? 115.524 128.416 106.945 1.00 69.88  ? 93  ALA R C   1 
ATOM 407  O O   . ALA A 1 149 ? 114.876 128.975 106.049 1.00 73.30  ? 93  ALA R O   1 
ATOM 408  C CB  . ALA A 1 149 ? 117.705 129.310 107.810 1.00 59.07  ? 93  ALA R CB  1 
ATOM 409  N N   . ASP A 1 150 ? 115.644 127.087 107.013 1.00 74.02  ? 94  ASP R N   1 
ATOM 410  C CA  . ASP A 1 150 ? 115.020 126.238 106.003 1.00 76.41  ? 94  ASP R CA  1 
ATOM 411  C C   . ASP A 1 150 ? 113.500 126.345 106.050 1.00 76.94  ? 94  ASP R C   1 
ATOM 412  O O   . ASP A 1 150 ? 112.836 126.316 105.007 1.00 80.83  ? 94  ASP R O   1 
ATOM 413  C CB  . ASP A 1 150 ? 115.462 124.791 106.193 1.00 75.21  ? 94  ASP R CB  1 
ATOM 414  C CG  . ASP A 1 150 ? 116.915 124.581 105.840 1.00 80.06  ? 94  ASP R CG  1 
ATOM 415  O OD1 . ASP A 1 150 ? 117.608 125.580 105.558 1.00 80.96  ? 94  ASP R OD1 1 
ATOM 416  O OD2 . ASP A 1 150 ? 117.366 123.418 105.846 1.00 82.02  ? 94  ASP R OD2 1 
ATOM 417  N N   . LEU A 1 151 ? 112.932 126.462 107.251 1.00 80.30  ? 95  LEU R N   1 
ATOM 418  C CA  . LEU A 1 151 ? 111.485 126.580 107.386 1.00 81.78  ? 95  LEU R CA  1 
ATOM 419  C C   . LEU A 1 151 ? 110.975 127.868 106.756 1.00 78.16  ? 95  LEU R C   1 
ATOM 420  O O   . LEU A 1 151 ? 109.973 127.856 106.032 1.00 76.28  ? 95  LEU R O   1 
ATOM 421  C CB  . LEU A 1 151 ? 111.095 126.506 108.862 1.00 77.27  ? 95  LEU R CB  1 
ATOM 422  C CG  . LEU A 1 151 ? 109.615 126.675 109.202 1.00 81.32  ? 95  LEU R CG  1 
ATOM 423  C CD1 . LEU A 1 151 ? 108.761 125.754 108.350 1.00 82.09  ? 95  LEU R CD1 1 
ATOM 424  C CD2 . LEU A 1 151 ? 109.380 126.410 110.679 1.00 80.49  ? 95  LEU R CD2 1 
ATOM 425  N N   . LEU A 1 152 ? 111.653 128.990 107.006 1.00 73.92  ? 96  LEU R N   1 
ATOM 426  C CA  . LEU A 1 152 ? 111.221 130.233 106.371 1.00 73.06  ? 96  LEU R CA  1 
ATOM 427  C C   . LEU A 1 152 ? 111.417 130.175 104.858 1.00 75.92  ? 96  LEU R C   1 
ATOM 428  O O   . LEU A 1 152 ? 110.605 130.724 104.100 1.00 82.94  ? 96  LEU R O   1 
ATOM 429  C CB  . LEU A 1 152 ? 111.954 131.433 106.969 1.00 70.21  ? 96  LEU R CB  1 
ATOM 430  C CG  . LEU A 1 152 ? 111.766 131.763 108.448 1.00 74.01  ? 96  LEU R CG  1 
ATOM 431  C CD1 . LEU A 1 152 ? 113.107 132.068 109.088 1.00 73.03  ? 96  LEU R CD1 1 
ATOM 432  C CD2 . LEU A 1 152 ? 110.813 132.933 108.616 1.00 80.38  ? 96  LEU R CD2 1 
ATOM 433  N N   . PHE A 1 153 ? 112.481 129.512 104.395 1.00 76.14  ? 97  PHE R N   1 
ATOM 434  C CA  . PHE A 1 153 ? 112.680 129.362 102.956 1.00 80.53  ? 97  PHE R CA  1 
ATOM 435  C C   . PHE A 1 153 ? 111.529 128.582 102.329 1.00 84.19  ? 97  PHE R C   1 
ATOM 436  O O   . PHE A 1 153 ? 110.986 128.970 101.284 1.00 86.29  ? 97  PHE R O   1 
ATOM 437  C CB  . PHE A 1 153 ? 114.019 128.671 102.691 1.00 80.51  ? 97  PHE R CB  1 
ATOM 438  C CG  . PHE A 1 153 ? 114.432 128.671 101.249 1.00 82.20  ? 97  PHE R CG  1 
ATOM 439  C CD1 . PHE A 1 153 ? 114.030 127.658 100.396 1.00 82.76  ? 97  PHE R CD1 1 
ATOM 440  C CD2 . PHE A 1 153 ? 115.235 129.680 100.748 1.00 81.84  ? 97  PHE R CD2 1 
ATOM 441  C CE1 . PHE A 1 153 ? 114.414 127.657 99.071  1.00 84.11  ? 97  PHE R CE1 1 
ATOM 442  C CE2 . PHE A 1 153 ? 115.623 129.683 99.424  1.00 83.44  ? 97  PHE R CE2 1 
ATOM 443  C CZ  . PHE A 1 153 ? 115.212 128.670 98.585  1.00 84.55  ? 97  PHE R CZ  1 
ATOM 444  N N   . ALA A 1 154 ? 111.131 127.481 102.970 1.00 87.47  ? 98  ALA R N   1 
ATOM 445  C CA  . ALA A 1 154 ? 109.967 126.735 102.505 1.00 88.84  ? 98  ALA R CA  1 
ATOM 446  C C   . ALA A 1 154 ? 108.709 127.588 102.555 1.00 89.71  ? 98  ALA R C   1 
ATOM 447  O O   . ALA A 1 154 ? 107.834 127.454 101.693 1.00 90.24  ? 98  ALA R O   1 
ATOM 448  C CB  . ALA A 1 154 ? 109.787 125.466 103.338 1.00 89.94  ? 98  ALA R CB  1 
ATOM 449  N N   . LEU A 1 155 ? 108.603 128.469 103.551 1.00 87.50  ? 99  LEU R N   1 
ATOM 450  C CA  . LEU A 1 155 ? 107.460 129.373 103.626 1.00 85.66  ? 99  LEU R CA  1 
ATOM 451  C C   . LEU A 1 155 ? 107.394 130.281 102.403 1.00 82.94  ? 99  LEU R C   1 
ATOM 452  O O   . LEU A 1 155 ? 106.313 130.514 101.851 1.00 84.88  ? 99  LEU R O   1 
ATOM 453  C CB  . LEU A 1 155 ? 107.535 130.202 104.908 1.00 85.26  ? 99  LEU R CB  1 
ATOM 454  C CG  . LEU A 1 155 ? 106.226 130.746 105.480 1.00 86.62  ? 99  LEU R CG  1 
ATOM 455  C CD1 . LEU A 1 155 ? 105.415 129.630 106.118 1.00 85.92  ? 99  LEU R CD1 1 
ATOM 456  C CD2 . LEU A 1 155 ? 106.505 131.852 106.485 1.00 84.47  ? 99  LEU R CD2 1 
ATOM 457  N N   . THR A 1 156 ? 108.540 130.810 101.970 1.00 84.07  ? 100 THR R N   1 
ATOM 458  C CA  . THR A 1 156 ? 108.549 131.662 100.781 1.00 87.76  ? 100 THR R CA  1 
ATOM 459  C C   . THR A 1 156 ? 108.454 130.879 99.475  1.00 86.86  ? 100 THR R C   1 
ATOM 460  O O   . THR A 1 156 ? 108.185 131.483 98.431  1.00 86.81  ? 100 THR R O   1 
ATOM 461  C CB  . THR A 1 156 ? 109.802 132.544 100.730 1.00 89.02  ? 100 THR R CB  1 
ATOM 462  O OG1 . THR A 1 156 ? 110.861 131.845 100.064 1.00 86.26  ? 100 THR R OG1 1 
ATOM 463  C CG2 . THR A 1 156 ? 110.241 132.966 102.116 1.00 88.76  ? 100 THR R CG2 1 
ATOM 464  N N   . LEU A 1 157 ? 108.685 129.564 99.503  1.00 95.74  ? 101 LEU R N   1 
ATOM 465  C CA  . LEU A 1 157 ? 108.666 128.782 98.264  1.00 99.74  ? 101 LEU R CA  1 
ATOM 466  C C   . LEU A 1 157 ? 107.361 128.873 97.470  1.00 103.44 ? 101 LEU R C   1 
ATOM 467  O O   . LEU A 1 157 ? 107.430 129.060 96.241  1.00 104.45 ? 101 LEU R O   1 
ATOM 468  C CB  . LEU A 1 157 ? 109.011 127.322 98.577  1.00 94.90  ? 101 LEU R CB  1 
ATOM 469  C CG  . LEU A 1 157 ? 110.497 126.997 98.744  1.00 98.34  ? 101 LEU R CG  1 
ATOM 470  C CD1 . LEU A 1 157 ? 110.690 125.554 99.176  1.00 101.48 ? 101 LEU R CD1 1 
ATOM 471  C CD2 . LEU A 1 157 ? 111.265 127.284 97.470  1.00 96.86  ? 101 LEU R CD2 1 
ATOM 472  N N   . PRO A 1 158 ? 106.166 128.725 98.064  1.00 100.87 ? 102 PRO R N   1 
ATOM 473  C CA  . PRO A 1 158 ? 104.943 128.710 97.234  1.00 96.87  ? 102 PRO R CA  1 
ATOM 474  C C   . PRO A 1 158 ? 104.713 129.980 96.430  1.00 96.24  ? 102 PRO R C   1 
ATOM 475  O O   . PRO A 1 158 ? 104.144 129.913 95.331  1.00 99.32  ? 102 PRO R O   1 
ATOM 476  C CB  . PRO A 1 158 ? 103.826 128.490 98.264  1.00 96.06  ? 102 PRO R CB  1 
ATOM 477  C CG  . PRO A 1 158 ? 104.493 127.816 99.399  1.00 96.86  ? 102 PRO R CG  1 
ATOM 478  C CD  . PRO A 1 158 ? 105.851 128.439 99.475  1.00 96.58  ? 102 PRO R CD  1 
ATOM 479  N N   . ILE A 1 159 ? 105.120 131.141 96.945  1.00 100.40 ? 103 ILE R N   1 
ATOM 480  C CA  . ILE A 1 159 ? 104.983 132.372 96.172  1.00 101.93 ? 103 ILE R CA  1 
ATOM 481  C C   . ILE A 1 159 ? 105.843 132.303 94.918  1.00 102.95 ? 103 ILE R C   1 
ATOM 482  O O   . ILE A 1 159 ? 105.425 132.724 93.832  1.00 103.74 ? 103 ILE R O   1 
ATOM 483  C CB  . ILE A 1 159 ? 105.332 133.596 97.038  1.00 103.59 ? 103 ILE R CB  1 
ATOM 484  C CG1 . ILE A 1 159 ? 104.535 133.579 98.345  1.00 102.40 ? 103 ILE R CG1 1 
ATOM 485  C CG2 . ILE A 1 159 ? 105.062 134.881 96.274  1.00 103.90 ? 103 ILE R CG2 1 
ATOM 486  C CD1 . ILE A 1 159 ? 103.059 133.265 98.172  1.00 102.69 ? 103 ILE R CD1 1 
ATOM 487  N N   . TRP A 1 160 ? 107.057 131.761 95.043  1.00 98.12  ? 104 TRP R N   1 
ATOM 488  C CA  . TRP A 1 160 ? 107.890 131.552 93.865  1.00 98.19  ? 104 TRP R CA  1 
ATOM 489  C C   . TRP A 1 160 ? 107.274 130.529 92.919  1.00 100.36 ? 104 TRP R C   1 
ATOM 490  O O   . TRP A 1 160 ? 107.418 130.653 91.698  1.00 106.33 ? 104 TRP R O   1 
ATOM 491  C CB  . TRP A 1 160 ? 109.294 131.115 94.279  1.00 100.50 ? 104 TRP R CB  1 
ATOM 492  C CG  . TRP A 1 160 ? 110.372 131.782 93.487  1.00 102.32 ? 104 TRP R CG  1 
ATOM 493  C CD1 . TRP A 1 160 ? 111.118 131.229 92.489  1.00 102.31 ? 104 TRP R CD1 1 
ATOM 494  C CD2 . TRP A 1 160 ? 110.824 133.134 93.624  1.00 101.73 ? 104 TRP R CD2 1 
ATOM 495  N NE1 . TRP A 1 160 ? 112.009 132.152 91.997  1.00 102.42 ? 104 TRP R NE1 1 
ATOM 496  C CE2 . TRP A 1 160 ? 111.848 133.330 92.678  1.00 102.87 ? 104 TRP R CE2 1 
ATOM 497  C CE3 . TRP A 1 160 ? 110.463 134.197 94.456  1.00 101.05 ? 104 TRP R CE3 1 
ATOM 498  C CZ2 . TRP A 1 160 ? 112.514 134.546 92.540  1.00 102.10 ? 104 TRP R CZ2 1 
ATOM 499  C CZ3 . TRP A 1 160 ? 111.125 135.403 94.318  1.00 100.34 ? 104 TRP R CZ3 1 
ATOM 500  C CH2 . TRP A 1 160 ? 112.139 135.567 93.368  1.00 99.72  ? 104 TRP R CH2 1 
ATOM 501  N N   . ALA A 1 161 ? 106.594 129.514 93.457  1.00 95.26  ? 105 ALA R N   1 
ATOM 502  C CA  . ALA A 1 161 ? 105.895 128.566 92.592  1.00 98.12  ? 105 ALA R CA  1 
ATOM 503  C C   . ALA A 1 161 ? 104.812 129.263 91.774  1.00 97.70  ? 105 ALA R C   1 
ATOM 504  O O   . ALA A 1 161 ? 104.679 129.027 90.567  1.00 93.64  ? 105 ALA R O   1 
ATOM 505  C CB  . ALA A 1 161 ? 105.296 127.436 93.427  1.00 98.13  ? 105 ALA R CB  1 
ATOM 506  N N   . ALA A 1 162 ? 104.036 130.137 92.415  1.00 104.37 ? 106 ALA R N   1 
ATOM 507  C CA  . ALA A 1 162 ? 103.022 130.897 91.688  1.00 103.81 ? 106 ALA R CA  1 
ATOM 508  C C   . ALA A 1 162 ? 103.662 131.831 90.665  1.00 103.20 ? 106 ALA R C   1 
ATOM 509  O O   . ALA A 1 162 ? 103.117 132.043 89.571  1.00 102.99 ? 106 ALA R O   1 
ATOM 510  C CB  . ALA A 1 162 ? 102.151 131.681 92.667  1.00 101.91 ? 106 ALA R CB  1 
ATOM 511  N N   . SER A 1 163 ? 104.813 132.410 91.011  1.00 103.93 ? 107 SER R N   1 
ATOM 512  C CA  . SER A 1 163 ? 105.544 133.240 90.059  1.00 103.43 ? 107 SER R CA  1 
ATOM 513  C C   . SER A 1 163 ? 105.931 132.438 88.823  1.00 101.60 ? 107 SER R C   1 
ATOM 514  O O   . SER A 1 163 ? 105.760 132.897 87.690  1.00 101.52 ? 107 SER R O   1 
ATOM 515  C CB  . SER A 1 163 ? 106.787 133.828 90.724  1.00 104.55 ? 107 SER R CB  1 
ATOM 516  O OG  . SER A 1 163 ? 107.462 134.712 89.846  1.00 105.36 ? 107 SER R OG  1 
ATOM 517  N N   . LYS A 1 164 ? 106.450 131.227 89.024  1.00 102.03 ? 108 LYS R N   1 
ATOM 518  C CA  . LYS A 1 164 ? 106.752 130.370 87.883  1.00 104.00 ? 108 LYS R CA  1 
ATOM 519  C C   . LYS A 1 164 ? 105.484 129.982 87.132  1.00 106.08 ? 108 LYS R C   1 
ATOM 520  O O   . LYS A 1 164 ? 105.539 129.702 85.929  1.00 104.07 ? 108 LYS R O   1 
ATOM 521  C CB  . LYS A 1 164 ? 107.512 129.124 88.338  1.00 106.23 ? 108 LYS R CB  1 
ATOM 522  C CG  . LYS A 1 164 ? 108.755 129.427 89.157  1.00 103.47 ? 108 LYS R CG  1 
ATOM 523  C CD  . LYS A 1 164 ? 110.024 129.119 88.384  1.00 105.37 ? 108 LYS R CD  1 
ATOM 524  C CE  . LYS A 1 164 ? 111.232 129.760 89.046  1.00 105.79 ? 108 LYS R CE  1 
ATOM 525  N NZ  . LYS A 1 164 ? 112.472 129.586 88.241  1.00 106.69 ? 108 LYS R NZ  1 
ATOM 526  N N   . VAL A 1 165 ? 104.342 129.952 87.823  1.00 105.42 ? 109 VAL R N   1 
ATOM 527  C CA  . VAL A 1 165 ? 103.074 129.687 87.145  1.00 104.21 ? 109 VAL R CA  1 
ATOM 528  C C   . VAL A 1 165 ? 102.754 130.802 86.156  1.00 103.91 ? 109 VAL R C   1 
ATOM 529  O O   . VAL A 1 165 ? 102.494 130.550 84.973  1.00 103.16 ? 109 VAL R O   1 
ATOM 530  C CB  . VAL A 1 165 ? 101.935 129.512 88.166  1.00 103.78 ? 109 VAL R CB  1 
ATOM 531  C CG1 . VAL A 1 165 ? 100.588 129.827 87.525  1.00 103.00 ? 109 VAL R CG1 1 
ATOM 532  C CG2 . VAL A 1 165 ? 101.923 128.112 88.723  1.00 105.22 ? 109 VAL R CG2 1 
ATOM 533  N N   . ASN A 1 166 ? 102.775 132.058 86.622  1.00 109.01 ? 110 ASN R N   1 
ATOM 534  C CA  . ASN A 1 166 ? 102.246 133.134 85.786  1.00 110.54 ? 110 ASN R CA  1 
ATOM 535  C C   . ASN A 1 166 ? 103.062 134.421 85.881  1.00 109.51 ? 110 ASN R C   1 
ATOM 536  O O   . ASN A 1 166 ? 102.524 135.511 85.661  1.00 109.15 ? 110 ASN R O   1 
ATOM 537  C CB  . ASN A 1 166 ? 100.786 133.429 86.139  1.00 111.03 ? 110 ASN R CB  1 
ATOM 538  C CG  . ASN A 1 166 ? 99.981  133.901 84.943  1.00 109.45 ? 110 ASN R CG  1 
ATOM 539  O OD1 . ASN A 1 166 ? 100.540 134.318 83.929  1.00 110.09 ? 110 ASN R OD1 1 
ATOM 540  N ND2 . ASN A 1 166 ? 98.660  133.837 85.057  1.00 107.17 ? 110 ASN R ND2 1 
ATOM 541  N N   . GLY A 1 167 ? 104.345 134.329 86.200  1.00 111.84 ? 111 GLY R N   1 
ATOM 542  C CA  . GLY A 1 167 ? 105.130 135.533 86.373  1.00 113.80 ? 111 GLY R CA  1 
ATOM 543  C C   . GLY A 1 167 ? 104.804 136.211 87.691  1.00 115.20 ? 111 GLY R C   1 
ATOM 544  O O   . GLY A 1 167 ? 104.068 135.686 88.531  1.00 115.26 ? 111 GLY R O   1 
ATOM 545  N N   . TRP A 1 168 ? 105.363 137.405 87.871  1.00 114.10 ? 112 TRP R N   1 
ATOM 546  C CA  . TRP A 1 168 ? 105.105 138.180 89.083  1.00 113.00 ? 112 TRP R CA  1 
ATOM 547  C C   . TRP A 1 168 ? 103.953 139.138 88.813  1.00 115.85 ? 112 TRP R C   1 
ATOM 548  O O   . TRP A 1 168 ? 104.148 140.234 88.282  1.00 115.67 ? 112 TRP R O   1 
ATOM 549  C CB  . TRP A 1 168 ? 106.348 138.929 89.546  1.00 112.40 ? 112 TRP R CB  1 
ATOM 550  C CG  . TRP A 1 168 ? 106.322 139.158 91.020  1.00 113.62 ? 112 TRP R CG  1 
ATOM 551  C CD1 . TRP A 1 168 ? 105.886 140.273 91.670  1.00 114.54 ? 112 TRP R CD1 1 
ATOM 552  C CD2 . TRP A 1 168 ? 106.726 138.233 92.035  1.00 115.37 ? 112 TRP R CD2 1 
ATOM 553  N NE1 . TRP A 1 168 ? 106.000 140.103 93.028  1.00 114.69 ? 112 TRP R NE1 1 
ATOM 554  C CE2 . TRP A 1 168 ? 106.515 138.858 93.278  1.00 114.75 ? 112 TRP R CE2 1 
ATOM 555  C CE3 . TRP A 1 168 ? 107.252 136.940 92.013  1.00 115.91 ? 112 TRP R CE3 1 
ATOM 556  C CZ2 . TRP A 1 168 ? 106.809 138.232 94.487  1.00 115.15 ? 112 TRP R CZ2 1 
ATOM 557  C CZ3 . TRP A 1 168 ? 107.545 136.321 93.213  1.00 115.67 ? 112 TRP R CZ3 1 
ATOM 558  C CH2 . TRP A 1 168 ? 107.325 136.968 94.433  1.00 115.48 ? 112 TRP R CH2 1 
ATOM 559  N N   . ILE A 1 169 ? 102.744 138.718 89.183  1.00 119.74 ? 113 ILE R N   1 
ATOM 560  C CA  . ILE A 1 169 ? 101.561 139.563 89.108  1.00 118.56 ? 113 ILE R CA  1 
ATOM 561  C C   . ILE A 1 169 ? 101.130 140.048 90.487  1.00 115.37 ? 113 ILE R C   1 
ATOM 562  O O   . ILE A 1 169 ? 100.030 140.587 90.636  1.00 116.49 ? 113 ILE R O   1 
ATOM 563  C CB  . ILE A 1 169 ? 100.410 138.831 88.404  1.00 118.98 ? 113 ILE R CB  1 
ATOM 564  C CG1 . ILE A 1 169 ? 100.150 137.485 89.088  1.00 117.50 ? 113 ILE R CG1 1 
ATOM 565  C CG2 . ILE A 1 169 ? 100.723 138.642 86.927  1.00 117.78 ? 113 ILE R CG2 1 
ATOM 566  C CD1 . ILE A 1 169 ? 99.357  136.505 88.249  1.00 118.10 ? 113 ILE R CD1 1 
ATOM 567  N N   . PHE A 1 170 ? 101.973 139.865 91.500  1.00 110.79 ? 114 PHE R N   1 
ATOM 568  C CA  . PHE A 1 170 ? 101.607 140.112 92.887  1.00 114.86 ? 114 PHE R CA  1 
ATOM 569  C C   . PHE A 1 170 ? 101.999 141.499 93.379  1.00 115.98 ? 114 PHE R C   1 
ATOM 570  O O   . PHE A 1 170 ? 101.717 141.831 94.535  1.00 115.51 ? 114 PHE R O   1 
ATOM 571  C CB  . PHE A 1 170 ? 102.241 139.046 93.787  1.00 115.02 ? 114 PHE R CB  1 
ATOM 572  C CG  . PHE A 1 170 ? 101.827 137.640 93.448  1.00 114.88 ? 114 PHE R CG  1 
ATOM 573  C CD1 . PHE A 1 170 ? 100.625 137.390 92.807  1.00 113.69 ? 114 PHE R CD1 1 
ATOM 574  C CD2 . PHE A 1 170 ? 102.646 136.569 93.764  1.00 114.70 ? 114 PHE R CD2 1 
ATOM 575  C CE1 . PHE A 1 170 ? 100.247 136.101 92.493  1.00 112.96 ? 114 PHE R CE1 1 
ATOM 576  C CE2 . PHE A 1 170 ? 102.272 135.278 93.451  1.00 114.97 ? 114 PHE R CE2 1 
ATOM 577  C CZ  . PHE A 1 170 ? 101.071 135.044 92.815  1.00 114.35 ? 114 PHE R CZ  1 
ATOM 578  N N   . GLY A 1 171 ? 102.633 142.313 92.544  1.00 113.56 ? 115 GLY R N   1 
ATOM 579  C CA  . GLY A 1 171 ? 103.012 143.659 92.920  1.00 113.07 ? 115 GLY R CA  1 
ATOM 580  C C   . GLY A 1 171 ? 104.488 143.775 93.260  1.00 113.09 ? 115 GLY R C   1 
ATOM 581  O O   . GLY A 1 171 ? 105.209 142.789 93.432  1.00 115.59 ? 115 GLY R O   1 
ATOM 582  N N   . THR A 1 172 ? 104.937 145.028 93.356  1.00 112.14 ? 116 THR R N   1 
ATOM 583  C CA  . THR A 1 172 ? 106.345 145.303 93.624  1.00 114.95 ? 116 THR R CA  1 
ATOM 584  C C   . THR A 1 172 ? 106.699 145.071 95.090  1.00 114.10 ? 116 THR R C   1 
ATOM 585  O O   . THR A 1 172 ? 107.796 144.588 95.396  1.00 114.57 ? 116 THR R O   1 
ATOM 586  C CB  . THR A 1 172 ? 106.682 146.737 93.211  1.00 115.61 ? 116 THR R CB  1 
ATOM 587  O OG1 . THR A 1 172 ? 106.464 146.891 91.803  1.00 114.36 ? 116 THR R OG1 1 
ATOM 588  C CG2 . THR A 1 172 ? 108.136 147.063 93.522  1.00 114.12 ? 116 THR R CG2 1 
ATOM 589  N N   . PHE A 1 173 ? 105.789 145.410 96.008  1.00 106.81 ? 117 PHE R N   1 
ATOM 590  C CA  . PHE A 1 173 ? 106.067 145.223 97.430  1.00 107.98 ? 117 PHE R CA  1 
ATOM 591  C C   . PHE A 1 173 ? 106.257 143.750 97.768  1.00 111.70 ? 117 PHE R C   1 
ATOM 592  O O   . PHE A 1 173 ? 107.177 143.388 98.515  1.00 113.16 ? 117 PHE R O   1 
ATOM 593  C CB  . PHE A 1 173 ? 104.938 145.823 98.266  1.00 108.28 ? 117 PHE R CB  1 
ATOM 594  C CG  . PHE A 1 173 ? 105.216 145.836 99.741  1.00 111.66 ? 117 PHE R CG  1 
ATOM 595  C CD1 . PHE A 1 173 ? 106.124 146.732 100.281 1.00 110.94 ? 117 PHE R CD1 1 
ATOM 596  C CD2 . PHE A 1 173 ? 104.568 144.953 100.588 1.00 110.84 ? 117 PHE R CD2 1 
ATOM 597  C CE1 . PHE A 1 173 ? 106.382 146.747 101.639 1.00 109.26 ? 117 PHE R CE1 1 
ATOM 598  C CE2 . PHE A 1 173 ? 104.821 144.963 101.946 1.00 111.20 ? 117 PHE R CE2 1 
ATOM 599  C CZ  . PHE A 1 173 ? 105.729 145.861 102.472 1.00 111.16 ? 117 PHE R CZ  1 
ATOM 600  N N   . LEU A 1 174 ? 105.396 142.885 97.228  1.00 109.51 ? 118 LEU R N   1 
ATOM 601  C CA  . LEU A 1 174 ? 105.553 141.453 97.451  1.00 109.04 ? 118 LEU R CA  1 
ATOM 602  C C   . LEU A 1 174 ? 106.840 140.939 96.820  1.00 111.84 ? 118 LEU R C   1 
ATOM 603  O O   . LEU A 1 174 ? 107.516 140.077 97.393  1.00 112.34 ? 118 LEU R O   1 
ATOM 604  C CB  . LEU A 1 174 ? 104.338 140.698 96.910  1.00 107.74 ? 118 LEU R CB  1 
ATOM 605  C CG  . LEU A 1 174 ? 103.108 140.741 97.820  1.00 109.41 ? 118 LEU R CG  1 
ATOM 606  C CD1 . LEU A 1 174 ? 101.960 139.929 97.244  1.00 109.82 ? 118 LEU R CD1 1 
ATOM 607  C CD2 . LEU A 1 174 ? 103.463 140.251 99.214  1.00 110.28 ? 118 LEU R CD2 1 
ATOM 608  N N   . CYS A 1 175 ? 107.194 141.455 95.640  1.00 113.18 ? 119 CYS R N   1 
ATOM 609  C CA  . CYS A 1 175 ? 108.482 141.123 95.036  1.00 112.72 ? 119 CYS R CA  1 
ATOM 610  C C   . CYS A 1 175 ? 109.628 141.434 95.988  1.00 112.96 ? 119 CYS R C   1 
ATOM 611  O O   . CYS A 1 175 ? 110.467 140.570 96.273  1.00 114.77 ? 119 CYS R O   1 
ATOM 612  C CB  . CYS A 1 175 ? 108.650 141.879 93.716  1.00 112.18 ? 119 CYS R CB  1 
ATOM 613  S SG  . CYS A 1 175 ? 110.353 142.038 93.098  1.00 115.88 ? 119 CYS R SG  1 
ATOM 614  N N   . LYS A 1 176 ? 109.662 142.662 96.510  1.00 105.22 ? 120 LYS R N   1 
ATOM 615  C CA  . LYS A 1 176 ? 110.735 143.055 97.416  1.00 105.84 ? 120 LYS R CA  1 
ATOM 616  C C   . LYS A 1 176 ? 110.777 142.152 98.642  1.00 104.84 ? 120 LYS R C   1 
ATOM 617  O O   . LYS A 1 176 ? 111.836 141.624 99.001  1.00 104.94 ? 120 LYS R O   1 
ATOM 618  C CB  . LYS A 1 176 ? 110.563 144.515 97.833  1.00 108.30 ? 120 LYS R CB  1 
ATOM 619  C CG  . LYS A 1 176 ? 110.856 145.524 96.736  1.00 108.08 ? 120 LYS R CG  1 
ATOM 620  C CD  . LYS A 1 176 ? 110.741 146.945 97.262  1.00 108.15 ? 120 LYS R CD  1 
ATOM 621  C CE  . LYS A 1 176 ? 111.324 147.948 96.284  1.00 107.98 ? 120 LYS R CE  1 
ATOM 622  N NZ  . LYS A 1 176 ? 112.804 147.823 96.186  1.00 107.17 ? 120 LYS R NZ  1 
ATOM 623  N N   . VAL A 1 177 ? 109.624 141.942 99.282  1.00 101.88 ? 121 VAL R N   1 
ATOM 624  C CA  . VAL A 1 177 ? 109.597 141.186 100.533 1.00 103.53 ? 121 VAL R CA  1 
ATOM 625  C C   . VAL A 1 177 ? 110.038 139.745 100.301 1.00 106.82 ? 121 VAL R C   1 
ATOM 626  O O   . VAL A 1 177 ? 110.912 139.221 101.007 1.00 106.56 ? 121 VAL R O   1 
ATOM 627  C CB  . VAL A 1 177 ? 108.196 141.252 101.168 1.00 104.31 ? 121 VAL R CB  1 
ATOM 628  C CG1 . VAL A 1 177 ? 107.992 140.099 102.140 1.00 103.54 ? 121 VAL R CG1 1 
ATOM 629  C CG2 . VAL A 1 177 ? 107.997 142.588 101.867 1.00 106.36 ? 121 VAL R CG2 1 
ATOM 630  N N   . VAL A 1 178 ? 109.447 139.085 99.300  1.00 107.41 ? 122 VAL R N   1 
ATOM 631  C CA  . VAL A 1 178 ? 109.733 137.675 99.058  1.00 105.84 ? 122 VAL R CA  1 
ATOM 632  C C   . VAL A 1 178 ? 111.188 137.489 98.646  1.00 106.64 ? 122 VAL R C   1 
ATOM 633  O O   . VAL A 1 178 ? 111.881 136.592 99.144  1.00 107.23 ? 122 VAL R O   1 
ATOM 634  C CB  . VAL A 1 178 ? 108.768 137.109 98.000  1.00 100.88 ? 122 VAL R CB  1 
ATOM 635  C CG1 . VAL A 1 178 ? 109.277 135.784 97.461  1.00 104.81 ? 122 VAL R CG1 1 
ATOM 636  C CG2 . VAL A 1 178 ? 107.376 136.949 98.588  1.00 101.34 ? 122 VAL R CG2 1 
ATOM 637  N N   . SER A 1 179 ? 111.677 138.335 97.734  1.00 103.13 ? 123 SER R N   1 
ATOM 638  C CA  . SER A 1 179 ? 113.055 138.200 97.278  1.00 102.54 ? 123 SER R CA  1 
ATOM 639  C C   . SER A 1 179 ? 114.041 138.452 98.412  1.00 105.51 ? 123 SER R C   1 
ATOM 640  O O   . SER A 1 179 ? 115.030 137.721 98.554  1.00 107.76 ? 123 SER R O   1 
ATOM 641  C CB  . SER A 1 179 ? 113.309 139.153 96.111  1.00 102.74 ? 123 SER R CB  1 
ATOM 642  O OG  . SER A 1 179 ? 112.356 138.963 95.081  1.00 103.81 ? 123 SER R OG  1 
ATOM 643  N N   . LEU A 1 180 ? 113.790 139.477 99.234  1.00 102.14 ? 124 LEU R N   1 
ATOM 644  C CA  . LEU A 1 180 ? 114.677 139.759 100.357 1.00 100.12 ? 124 LEU R CA  1 
ATOM 645  C C   . LEU A 1 180 ? 114.712 138.591 101.332 1.00 99.93  ? 124 LEU R C   1 
ATOM 646  O O   . LEU A 1 180 ? 115.788 138.165 101.768 1.00 99.51  ? 124 LEU R O   1 
ATOM 647  C CB  . LEU A 1 180 ? 114.230 141.036 101.068 1.00 100.98 ? 124 LEU R CB  1 
ATOM 648  C CG  . LEU A 1 180 ? 114.709 141.220 102.511 1.00 99.80  ? 124 LEU R CG  1 
ATOM 649  C CD1 . LEU A 1 180 ? 116.210 141.458 102.561 1.00 96.18  ? 124 LEU R CD1 1 
ATOM 650  C CD2 . LEU A 1 180 ? 113.955 142.354 103.191 1.00 102.73 ? 124 LEU R CD2 1 
ATOM 651  N N   . LEU A 1 181 ? 113.539 138.053 101.683 1.00 95.06  ? 125 LEU R N   1 
ATOM 652  C CA  . LEU A 1 181 ? 113.501 136.939 102.624 1.00 95.10  ? 125 LEU R CA  1 
ATOM 653  C C   . LEU A 1 181 ? 114.215 135.717 102.060 1.00 99.17  ? 125 LEU R C   1 
ATOM 654  O O   . LEU A 1 181 ? 114.985 135.055 102.770 1.00 98.49  ? 125 LEU R O   1 
ATOM 655  C CB  . LEU A 1 181 ? 112.053 136.605 102.979 1.00 93.54  ? 125 LEU R CB  1 
ATOM 656  C CG  . LEU A 1 181 ? 111.854 135.725 104.213 1.00 97.17  ? 125 LEU R CG  1 
ATOM 657  C CD1 . LEU A 1 181 ? 112.656 136.268 105.384 1.00 97.36  ? 125 LEU R CD1 1 
ATOM 658  C CD2 . LEU A 1 181 ? 110.381 135.636 104.571 1.00 98.39  ? 125 LEU R CD2 1 
ATOM 659  N N   . LYS A 1 182 ? 113.989 135.414 100.778 1.00 97.73  ? 126 LYS R N   1 
ATOM 660  C CA  . LYS A 1 182 ? 114.618 134.249 100.165 1.00 94.73  ? 126 LYS R CA  1 
ATOM 661  C C   . LYS A 1 182 ? 116.135 134.393 100.122 1.00 94.12  ? 126 LYS R C   1 
ATOM 662  O O   . LYS A 1 182 ? 116.864 133.448 100.449 1.00 96.68  ? 126 LYS R O   1 
ATOM 663  C CB  . LYS A 1 182 ? 114.056 134.038 98.760  1.00 91.35  ? 126 LYS R CB  1 
ATOM 664  C CG  . LYS A 1 182 ? 114.592 132.812 98.045  1.00 94.27  ? 126 LYS R CG  1 
ATOM 665  C CD  . LYS A 1 182 ? 113.755 132.494 96.816  1.00 94.66  ? 126 LYS R CD  1 
ATOM 666  C CE  . LYS A 1 182 ? 114.014 131.083 96.316  1.00 92.06  ? 126 LYS R CE  1 
ATOM 667  N NZ  . LYS A 1 182 ? 113.219 130.774 95.097  1.00 91.99  ? 126 LYS R NZ  1 
ATOM 668  N N   . GLU A 1 183 ? 116.630 135.569 99.724  1.00 85.51  ? 127 GLU R N   1 
ATOM 669  C CA  . GLU A 1 183 ? 118.074 135.776 99.666  1.00 84.95  ? 127 GLU R CA  1 
ATOM 670  C C   . GLU A 1 183 ? 118.698 135.720 101.056 1.00 88.79  ? 127 GLU R C   1 
ATOM 671  O O   . GLU A 1 183 ? 119.775 135.129 101.237 1.00 94.23  ? 127 GLU R O   1 
ATOM 672  C CB  . GLU A 1 183 ? 118.384 137.110 98.988  1.00 87.92  ? 127 GLU R CB  1 
ATOM 673  C CG  . GLU A 1 183 ? 119.793 137.217 98.414  1.00 91.66  ? 127 GLU R CG  1 
ATOM 674  C CD  . GLU A 1 183 ? 119.976 136.449 97.114  1.00 91.31  ? 127 GLU R CD  1 
ATOM 675  O OE1 . GLU A 1 183 ? 119.071 135.679 96.729  1.00 91.18  ? 127 GLU R OE1 1 
ATOM 676  O OE2 . GLU A 1 183 ? 121.034 136.618 96.473  1.00 87.51  ? 127 GLU R OE2 1 
ATOM 677  N N   . VAL A 1 184 ? 118.036 136.321 102.049 1.00 87.25  ? 128 VAL R N   1 
ATOM 678  C CA  . VAL A 1 184 ? 118.547 136.279 103.416 1.00 91.94  ? 128 VAL R CA  1 
ATOM 679  C C   . VAL A 1 184 ? 118.647 134.838 103.894 1.00 92.68  ? 128 VAL R C   1 
ATOM 680  O O   . VAL A 1 184 ? 119.656 134.428 104.479 1.00 92.74  ? 128 VAL R O   1 
ATOM 681  C CB  . VAL A 1 184 ? 117.661 137.122 104.351 1.00 89.80  ? 128 VAL R CB  1 
ATOM 682  C CG1 . VAL A 1 184 ? 117.906 136.741 105.803 1.00 89.34  ? 128 VAL R CG1 1 
ATOM 683  C CG2 . VAL A 1 184 ? 117.928 138.599 104.149 1.00 92.04  ? 128 VAL R CG2 1 
ATOM 684  N N   . ASN A 1 185 ? 117.603 134.046 103.643 1.00 80.95  ? 129 ASN R N   1 
ATOM 685  C CA  . ASN A 1 185 ? 117.619 132.656 104.083 1.00 76.60  ? 129 ASN R CA  1 
ATOM 686  C C   . ASN A 1 185 ? 118.694 131.849 103.372 1.00 79.34  ? 129 ASN R C   1 
ATOM 687  O O   . ASN A 1 185 ? 119.353 131.009 103.992 1.00 83.50  ? 129 ASN R O   1 
ATOM 688  C CB  . ASN A 1 185 ? 116.254 132.021 103.868 1.00 81.30  ? 129 ASN R CB  1 
ATOM 689  C CG  . ASN A 1 185 ? 115.328 132.265 105.021 1.00 89.57  ? 129 ASN R CG  1 
ATOM 690  O OD1 . ASN A 1 185 ? 115.415 133.285 105.705 1.00 85.79  ? 129 ASN R OD1 1 
ATOM 691  N ND2 . ASN A 1 185 ? 114.458 131.310 105.274 1.00 89.64  ? 129 ASN R ND2 1 
ATOM 692  N N   . PHE A 1 186 ? 118.872 132.070 102.070 1.00 76.39  ? 130 PHE R N   1 
ATOM 693  C CA  . PHE A 1 186 ? 119.905 131.349 101.334 1.00 73.51  ? 130 PHE R CA  1 
ATOM 694  C C   . PHE A 1 186 ? 121.286 131.643 101.913 1.00 73.82  ? 130 PHE R C   1 
ATOM 695  O O   . PHE A 1 186 ? 122.059 130.721 102.226 1.00 82.45  ? 130 PHE R O   1 
ATOM 696  C CB  . PHE A 1 186 ? 119.819 131.729 99.854  1.00 72.31  ? 130 PHE R CB  1 
ATOM 697  C CG  . PHE A 1 186 ? 121.055 131.429 99.063  1.00 67.86  ? 130 PHE R CG  1 
ATOM 698  C CD1 . PHE A 1 186 ? 121.575 130.149 99.017  1.00 72.34  ? 130 PHE R CD1 1 
ATOM 699  C CD2 . PHE A 1 186 ? 121.682 132.428 98.340  1.00 71.12  ? 130 PHE R CD2 1 
ATOM 700  C CE1 . PHE A 1 186 ? 122.706 129.877 98.276  1.00 77.66  ? 130 PHE R CE1 1 
ATOM 701  C CE2 . PHE A 1 186 ? 122.813 132.161 97.600  1.00 77.39  ? 130 PHE R CE2 1 
ATOM 702  C CZ  . PHE A 1 186 ? 123.326 130.885 97.568  1.00 80.33  ? 130 PHE R CZ  1 
ATOM 703  N N   . TYR A 1 187 ? 121.593 132.929 102.106 1.00 68.80  ? 131 TYR R N   1 
ATOM 704  C CA  . TYR A 1 187 ? 122.883 133.306 102.677 1.00 73.68  ? 131 TYR R CA  1 
ATOM 705  C C   . TYR A 1 187 ? 123.060 132.714 104.071 1.00 75.21  ? 131 TYR R C   1 
ATOM 706  O O   . TYR A 1 187 ? 124.124 132.172 104.400 1.00 74.92  ? 131 TYR R O   1 
ATOM 707  C CB  . TYR A 1 187 ? 123.002 134.827 102.732 1.00 72.30  ? 131 TYR R CB  1 
ATOM 708  C CG  . TYR A 1 187 ? 123.525 135.474 101.474 1.00 72.02  ? 131 TYR R CG  1 
ATOM 709  C CD1 . TYR A 1 187 ? 122.986 136.667 101.018 1.00 76.20  ? 131 TYR R CD1 1 
ATOM 710  C CD2 . TYR A 1 187 ? 124.565 134.908 100.754 1.00 72.17  ? 131 TYR R CD2 1 
ATOM 711  C CE1 . TYR A 1 187 ? 123.457 137.273 99.878  1.00 77.22  ? 131 TYR R CE1 1 
ATOM 712  C CE2 . TYR A 1 187 ? 125.046 135.509 99.609  1.00 74.57  ? 131 TYR R CE2 1 
ATOM 713  C CZ  . TYR A 1 187 ? 124.486 136.693 99.177  1.00 77.12  ? 131 TYR R CZ  1 
ATOM 714  O OH  . TYR A 1 187 ? 124.953 137.306 98.039  1.00 80.80  ? 131 TYR R OH  1 
ATOM 715  N N   . SER A 1 188 ? 122.020 132.810 104.905 1.00 71.69  ? 132 SER R N   1 
ATOM 716  C CA  . SER A 1 188 ? 122.117 132.331 106.278 1.00 69.44  ? 132 SER R CA  1 
ATOM 717  C C   . SER A 1 188 ? 122.326 130.826 106.325 1.00 67.52  ? 132 SER R C   1 
ATOM 718  O O   . SER A 1 188 ? 123.124 130.332 107.125 1.00 70.83  ? 132 SER R O   1 
ATOM 719  C CB  . SER A 1 188 ? 120.865 132.720 107.061 1.00 77.42  ? 132 SER R CB  1 
ATOM 720  O OG  . SER A 1 188 ? 120.783 134.124 107.225 1.00 80.98  ? 132 SER R OG  1 
ATOM 721  N N   . GLY A 1 189 ? 121.620 130.079 105.475 1.00 60.19  ? 133 GLY R N   1 
ATOM 722  C CA  . GLY A 1 189 ? 121.797 128.637 105.455 1.00 57.40  ? 133 GLY R CA  1 
ATOM 723  C C   . GLY A 1 189 ? 123.200 128.233 105.050 1.00 64.29  ? 133 GLY R C   1 
ATOM 724  O O   . GLY A 1 189 ? 123.817 127.364 105.677 1.00 73.62  ? 133 GLY R O   1 
ATOM 725  N N   . ILE A 1 190 ? 123.734 128.867 104.002 1.00 57.91  ? 134 ILE R N   1 
ATOM 726  C CA  . ILE A 1 190 ? 125.079 128.503 103.556 1.00 56.03  ? 134 ILE R CA  1 
ATOM 727  C C   . ILE A 1 190 ? 126.112 128.844 104.628 1.00 60.73  ? 134 ILE R C   1 
ATOM 728  O O   . ILE A 1 190 ? 127.004 128.039 104.945 1.00 62.04  ? 134 ILE R O   1 
ATOM 729  C CB  . ILE A 1 190 ? 125.408 129.178 102.214 1.00 50.35  ? 134 ILE R CB  1 
ATOM 730  C CG1 . ILE A 1 190 ? 124.308 128.898 101.193 1.00 50.79  ? 134 ILE R CG1 1 
ATOM 731  C CG2 . ILE A 1 190 ? 126.710 128.647 101.690 1.00 56.78  ? 134 ILE R CG2 1 
ATOM 732  C CD1 . ILE A 1 190 ? 124.397 127.535 100.551 1.00 58.46  ? 134 ILE R CD1 1 
ATOM 733  N N   . LEU A 1 191 ? 126.004 130.039 105.216 1.00 60.90  ? 135 LEU R N   1 
ATOM 734  C CA  . LEU A 1 191 ? 126.963 130.418 106.249 1.00 59.28  ? 135 LEU R CA  1 
ATOM 735  C C   . LEU A 1 191 ? 126.812 129.562 107.501 1.00 53.39  ? 135 LEU R C   1 
ATOM 736  O O   . LEU A 1 191 ? 127.799 129.315 108.203 1.00 59.84  ? 135 LEU R O   1 
ATOM 737  C CB  . LEU A 1 191 ? 126.818 131.901 106.583 1.00 62.71  ? 135 LEU R CB  1 
ATOM 738  C CG  . LEU A 1 191 ? 127.078 132.867 105.423 1.00 61.41  ? 135 LEU R CG  1 
ATOM 739  C CD1 . LEU A 1 191 ? 127.056 134.310 105.902 1.00 63.53  ? 135 LEU R CD1 1 
ATOM 740  C CD2 . LEU A 1 191 ? 128.396 132.547 104.731 1.00 57.74  ? 135 LEU R CD2 1 
ATOM 741  N N   . LEU A 1 192 ? 125.600 129.083 107.790 1.00 45.46  ? 136 LEU R N   1 
ATOM 742  C CA  . LEU A 1 192 ? 125.409 128.189 108.925 1.00 44.45  ? 136 LEU R CA  1 
ATOM 743  C C   . LEU A 1 192 ? 126.052 126.834 108.671 1.00 48.52  ? 136 LEU R C   1 
ATOM 744  O O   . LEU A 1 192 ? 126.608 126.224 109.590 1.00 55.19  ? 136 LEU R O   1 
ATOM 745  C CB  . LEU A 1 192 ? 123.920 128.032 109.222 1.00 51.11  ? 136 LEU R CB  1 
ATOM 746  C CG  . LEU A 1 192 ? 123.304 129.115 110.106 1.00 55.51  ? 136 LEU R CG  1 
ATOM 747  C CD1 . LEU A 1 192 ? 121.894 128.727 110.503 1.00 49.43  ? 136 LEU R CD1 1 
ATOM 748  C CD2 . LEU A 1 192 ? 124.164 129.357 111.335 1.00 54.79  ? 136 LEU R CD2 1 
ATOM 749  N N   . LEU A 1 193 ? 125.981 126.343 107.432 1.00 50.04  ? 137 LEU R N   1 
ATOM 750  C CA  . LEU A 1 193 ? 126.709 125.122 107.095 1.00 49.09  ? 137 LEU R CA  1 
ATOM 751  C C   . LEU A 1 193 ? 128.208 125.313 107.293 1.00 48.19  ? 137 LEU R C   1 
ATOM 752  O O   . LEU A 1 193 ? 128.892 124.440 107.850 1.00 51.46  ? 137 LEU R O   1 
ATOM 753  C CB  . LEU A 1 193 ? 126.407 124.704 105.657 1.00 47.38  ? 137 LEU R CB  1 
ATOM 754  C CG  . LEU A 1 193 ? 124.951 124.385 105.314 1.00 46.71  ? 137 LEU R CG  1 
ATOM 755  C CD1 . LEU A 1 193 ? 124.859 123.707 103.960 1.00 46.64  ? 137 LEU R CD1 1 
ATOM 756  C CD2 . LEU A 1 193 ? 124.325 123.519 106.390 1.00 52.21  ? 137 LEU R CD2 1 
ATOM 757  N N   . ALA A 1 194 ? 128.732 126.462 106.856 1.00 48.36  ? 138 ALA R N   1 
ATOM 758  C CA  . ALA A 1 194 ? 130.152 126.743 107.057 1.00 44.32  ? 138 ALA R CA  1 
ATOM 759  C C   . ALA A 1 194 ? 130.510 126.780 108.541 1.00 45.12  ? 138 ALA R C   1 
ATOM 760  O O   . ALA A 1 194 ? 131.541 126.231 108.956 1.00 46.15  ? 138 ALA R O   1 
ATOM 761  C CB  . ALA A 1 194 ? 130.529 128.060 106.382 1.00 47.70  ? 138 ALA R CB  1 
ATOM 762  N N   . CYS A 1 195 ? 129.668 127.418 109.357 1.00 49.03  ? 139 CYS R N   1 
ATOM 763  C CA  . CYS A 1 195 ? 129.939 127.507 110.789 1.00 46.53  ? 139 CYS R CA  1 
ATOM 764  C C   . CYS A 1 195 ? 129.864 126.140 111.463 1.00 53.35  ? 139 CYS R C   1 
ATOM 765  O O   . CYS A 1 195 ? 130.641 125.853 112.381 1.00 56.35  ? 139 CYS R O   1 
ATOM 766  C CB  . CYS A 1 195 ? 128.968 128.485 111.445 1.00 50.47  ? 139 CYS R CB  1 
ATOM 767  S SG  . CYS A 1 195 ? 129.293 130.217 111.049 1.00 78.40  ? 139 CYS R SG  1 
ATOM 768  N N   . ILE A 1 196 ? 128.930 125.289 111.033 1.00 42.83  ? 140 ILE R N   1 
ATOM 769  C CA  . ILE A 1 196 ? 128.855 123.932 111.571 1.00 32.84  ? 140 ILE R CA  1 
ATOM 770  C C   . ILE A 1 196 ? 130.130 123.162 111.248 1.00 38.78  ? 140 ILE R C   1 
ATOM 771  O O   . ILE A 1 196 ? 130.676 122.444 112.100 1.00 40.09  ? 140 ILE R O   1 
ATOM 772  C CB  . ILE A 1 196 ? 127.605 123.213 111.032 1.00 33.75  ? 140 ILE R CB  1 
ATOM 773  C CG1 . ILE A 1 196 ? 126.379 123.574 111.870 1.00 40.04  ? 140 ILE R CG1 1 
ATOM 774  C CG2 . ILE A 1 196 ? 127.809 121.710 111.016 1.00 44.54  ? 140 ILE R CG2 1 
ATOM 775  C CD1 . ILE A 1 196 ? 125.074 123.106 111.271 1.00 45.10  ? 140 ILE R CD1 1 
ATOM 776  N N   . SER A 1 197 ? 130.622 123.292 110.013 1.00 54.33  ? 141 SER R N   1 
ATOM 777  C CA  . SER A 1 197 ? 131.875 122.631 109.659 1.00 44.94  ? 141 SER R CA  1 
ATOM 778  C C   . SER A 1 197 ? 133.028 123.147 110.511 1.00 38.04  ? 141 SER R C   1 
ATOM 779  O O   . SER A 1 197 ? 133.884 122.368 110.951 1.00 50.59  ? 141 SER R O   1 
ATOM 780  C CB  . SER A 1 197 ? 132.178 122.827 108.175 1.00 53.45  ? 141 SER R CB  1 
ATOM 781  O OG  . SER A 1 197 ? 131.790 124.116 107.743 1.00 58.73  ? 141 SER R OG  1 
ATOM 782  N N   . VAL A 1 198 ? 133.068 124.460 110.753 1.00 35.74  ? 142 VAL R N   1 
ATOM 783  C CA  . VAL A 1 198 ? 134.112 125.032 111.602 1.00 43.34  ? 142 VAL R CA  1 
ATOM 784  C C   . VAL A 1 198 ? 134.031 124.456 113.012 1.00 48.84  ? 142 VAL R C   1 
ATOM 785  O O   . VAL A 1 198 ? 135.054 124.127 113.628 1.00 46.16  ? 142 VAL R O   1 
ATOM 786  C CB  . VAL A 1 198 ? 134.012 126.569 111.609 1.00 43.77  ? 142 VAL R CB  1 
ATOM 787  C CG1 . VAL A 1 198 ? 134.636 127.147 112.869 1.00 42.26  ? 142 VAL R CG1 1 
ATOM 788  C CG2 . VAL A 1 198 ? 134.684 127.143 110.380 1.00 42.64  ? 142 VAL R CG2 1 
ATOM 789  N N   . ASP A 1 199 ? 132.814 124.339 113.549 1.00 54.18  ? 143 ASP R N   1 
ATOM 790  C CA  . ASP A 1 199 ? 132.639 123.776 114.884 1.00 54.93  ? 143 ASP R CA  1 
ATOM 791  C C   . ASP A 1 199 ? 133.142 122.340 114.945 1.00 50.58  ? 143 ASP R C   1 
ATOM 792  O O   . ASP A 1 199 ? 133.829 121.956 115.897 1.00 45.60  ? 143 ASP R O   1 
ATOM 793  C CB  . ASP A 1 199 ? 131.167 123.843 115.293 1.00 59.90  ? 143 ASP R CB  1 
ATOM 794  C CG  . ASP A 1 199 ? 130.939 123.444 116.740 1.00 58.35  ? 143 ASP R CG  1 
ATOM 795  O OD1 . ASP A 1 199 ? 131.928 123.242 117.476 1.00 54.64  ? 143 ASP R OD1 1 
ATOM 796  O OD2 . ASP A 1 199 ? 129.763 123.325 117.143 1.00 58.84  ? 143 ASP R OD2 1 
ATOM 797  N N   . ARG A 1 200 ? 132.809 121.531 113.936 1.00 53.20  ? 144 ARG R N   1 
ATOM 798  C CA  . ARG A 1 200 ? 133.281 120.148 113.922 1.00 46.46  ? 144 ARG R CA  1 
ATOM 799  C C   . ARG A 1 200 ? 134.802 120.083 113.841 1.00 46.89  ? 144 ARG R C   1 
ATOM 800  O O   . ARG A 1 200 ? 135.436 119.263 114.520 1.00 53.41  ? 144 ARG R O   1 
ATOM 801  C CB  . ARG A 1 200 ? 132.645 119.384 112.763 1.00 39.58  ? 144 ARG R CB  1 
ATOM 802  C CG  . ARG A 1 200 ? 131.276 118.817 113.089 1.00 41.47  ? 144 ARG R CG  1 
ATOM 803  C CD  . ARG A 1 200 ? 130.448 118.614 111.836 1.00 47.78  ? 144 ARG R CD  1 
ATOM 804  N NE  . ARG A 1 200 ? 129.117 118.107 112.143 1.00 50.17  ? 144 ARG R NE  1 
ATOM 805  C CZ  . ARG A 1 200 ? 128.154 117.943 111.248 1.00 47.19  ? 144 ARG R CZ  1 
ATOM 806  N NH1 . ARG A 1 200 ? 128.335 118.248 109.974 1.00 47.90  ? 144 ARG R NH1 1 
ATOM 807  N NH2 . ARG A 1 200 ? 126.978 117.462 111.641 1.00 45.66  ? 144 ARG R NH2 1 
ATOM 808  N N   . TYR A 1 201 ? 135.406 120.948 113.021 1.00 45.91  ? 145 TYR R N   1 
ATOM 809  C CA  . TYR A 1 201 ? 136.861 120.981 112.915 1.00 44.95  ? 145 TYR R CA  1 
ATOM 810  C C   . TYR A 1 201 ? 137.500 121.320 114.255 1.00 52.83  ? 145 TYR R C   1 
ATOM 811  O O   . TYR A 1 201 ? 138.453 120.662 114.687 1.00 57.61  ? 145 TYR R O   1 
ATOM 812  C CB  . TYR A 1 201 ? 137.284 121.996 111.854 1.00 51.01  ? 145 TYR R CB  1 
ATOM 813  C CG  . TYR A 1 201 ? 138.741 122.399 111.921 1.00 50.93  ? 145 TYR R CG  1 
ATOM 814  C CD1 . TYR A 1 201 ? 139.748 121.446 111.928 1.00 50.85  ? 145 TYR R CD1 1 
ATOM 815  C CD2 . TYR A 1 201 ? 139.106 123.735 111.995 1.00 52.79  ? 145 TYR R CD2 1 
ATOM 816  C CE1 . TYR A 1 201 ? 141.077 121.811 111.994 1.00 50.43  ? 145 TYR R CE1 1 
ATOM 817  C CE2 . TYR A 1 201 ? 140.433 124.109 112.063 1.00 54.84  ? 145 TYR R CE2 1 
ATOM 818  C CZ  . TYR A 1 201 ? 141.413 123.143 112.062 1.00 54.21  ? 145 TYR R CZ  1 
ATOM 819  O OH  . TYR A 1 201 ? 142.735 123.514 112.130 1.00 55.73  ? 145 TYR R OH  1 
ATOM 820  N N   . LEU A 1 202 ? 136.984 122.348 114.932 1.00 56.46  ? 146 LEU R N   1 
ATOM 821  C CA  . LEU A 1 202 ? 137.551 122.738 116.219 1.00 58.05  ? 146 LEU R CA  1 
ATOM 822  C C   . LEU A 1 202 ? 137.240 121.735 117.321 1.00 56.31  ? 146 LEU R C   1 
ATOM 823  O O   . LEU A 1 202 ? 137.934 121.722 118.343 1.00 50.18  ? 146 LEU R O   1 
ATOM 824  C CB  . LEU A 1 202 ? 137.049 124.123 116.625 1.00 55.24  ? 146 LEU R CB  1 
ATOM 825  C CG  . LEU A 1 202 ? 137.581 125.291 115.798 1.00 52.53  ? 146 LEU R CG  1 
ATOM 826  C CD1 . LEU A 1 202 ? 137.017 126.608 116.305 1.00 54.59  ? 146 LEU R CD1 1 
ATOM 827  C CD2 . LEU A 1 202 ? 139.097 125.303 115.830 1.00 52.79  ? 146 LEU R CD2 1 
ATOM 828  N N   . ALA A 1 203 ? 136.218 120.901 117.143 1.00 53.92  ? 147 ALA R N   1 
ATOM 829  C CA  . ALA A 1 203 ? 135.857 119.934 118.168 1.00 49.61  ? 147 ALA R CA  1 
ATOM 830  C C   . ALA A 1 203 ? 136.603 118.615 118.039 1.00 49.01  ? 147 ALA R C   1 
ATOM 831  O O   . ALA A 1 203 ? 136.851 117.957 119.055 1.00 56.07  ? 147 ALA R O   1 
ATOM 832  C CB  . ALA A 1 203 ? 134.351 119.667 118.132 1.00 53.63  ? 147 ALA R CB  1 
ATOM 833  N N   . ILE A 1 204 ? 136.965 118.204 116.827 1.00 52.20  ? 148 ILE R N   1 
ATOM 834  C CA  . ILE A 1 204 ? 137.596 116.907 116.622 1.00 52.48  ? 148 ILE R CA  1 
ATOM 835  C C   . ILE A 1 204 ? 139.105 117.027 116.437 1.00 53.05  ? 148 ILE R C   1 
ATOM 836  O O   . ILE A 1 204 ? 139.858 116.200 116.949 1.00 49.10  ? 148 ILE R O   1 
ATOM 837  C CB  . ILE A 1 204 ? 136.941 116.175 115.433 1.00 45.30  ? 148 ILE R CB  1 
ATOM 838  C CG1 . ILE A 1 204 ? 135.470 115.908 115.739 1.00 46.99  ? 148 ILE R CG1 1 
ATOM 839  C CG2 . ILE A 1 204 ? 137.651 114.865 115.154 1.00 44.89  ? 148 ILE R CG2 1 
ATOM 840  C CD1 . ILE A 1 204 ? 134.724 115.276 114.605 1.00 53.72  ? 148 ILE R CD1 1 
ATOM 841  N N   . VAL A 1 205 ? 139.575 118.044 115.720 1.00 59.15  ? 149 VAL R N   1 
ATOM 842  C CA  . VAL A 1 205 ? 141.015 118.204 115.530 1.00 52.74  ? 149 VAL R CA  1 
ATOM 843  C C   . VAL A 1 205 ? 141.655 118.838 116.759 1.00 63.43  ? 149 VAL R C   1 
ATOM 844  O O   . VAL A 1 205 ? 142.555 118.261 117.379 1.00 66.61  ? 149 VAL R O   1 
ATOM 845  C CB  . VAL A 1 205 ? 141.307 119.016 114.257 1.00 52.89  ? 149 VAL R CB  1 
ATOM 846  C CG1 . VAL A 1 205 ? 142.804 119.178 114.075 1.00 59.22  ? 149 VAL R CG1 1 
ATOM 847  C CG2 . VAL A 1 205 ? 140.708 118.319 113.053 1.00 59.93  ? 149 VAL R CG2 1 
ATOM 848  N N   . HIS A 1 206 ? 141.202 120.036 117.129 1.00 70.35  ? 150 HIS R N   1 
ATOM 849  C CA  . HIS A 1 206 ? 141.704 120.719 118.323 1.00 64.63  ? 150 HIS R CA  1 
ATOM 850  C C   . HIS A 1 206 ? 140.824 120.361 119.522 1.00 66.05  ? 150 HIS R C   1 
ATOM 851  O O   . HIS A 1 206 ? 140.129 121.194 120.104 1.00 66.27  ? 150 HIS R O   1 
ATOM 852  C CB  . HIS A 1 206 ? 141.751 122.224 118.097 1.00 72.64  ? 150 HIS R CB  1 
ATOM 853  C CG  . HIS A 1 206 ? 142.764 122.658 117.085 1.00 74.07  ? 150 HIS R CG  1 
ATOM 854  N ND1 . HIS A 1 206 ? 144.118 122.655 117.340 1.00 74.06  ? 150 HIS R ND1 1 
ATOM 855  C CD2 . HIS A 1 206 ? 142.622 123.096 115.812 1.00 70.38  ? 150 HIS R CD2 1 
ATOM 856  C CE1 . HIS A 1 206 ? 144.767 123.077 116.270 1.00 72.94  ? 150 HIS R CE1 1 
ATOM 857  N NE2 . HIS A 1 206 ? 143.882 123.352 115.328 1.00 72.15  ? 150 HIS R NE2 1 
ATOM 858  N N   . ALA A 1 207 ? 140.870 119.082 119.889 1.00 69.77  ? 151 ALA R N   1 
ATOM 859  C CA  . ALA A 1 207 ? 140.020 118.579 120.962 1.00 71.61  ? 151 ALA R CA  1 
ATOM 860  C C   . ALA A 1 207 ? 140.712 118.619 122.319 1.00 69.85  ? 151 ALA R C   1 
ATOM 861  O O   . ALA A 1 207 ? 140.120 119.066 123.306 1.00 72.82  ? 151 ALA R O   1 
ATOM 862  C CB  . ALA A 1 207 ? 139.569 117.151 120.649 1.00 66.53  ? 151 ALA R CB  1 
ATOM 863  N N   . THR A 1 208 ? 141.958 118.151 122.387 1.00 72.29  ? 152 THR R N   1 
ATOM 864  C CA  . THR A 1 208 ? 142.670 118.125 123.659 1.00 73.00  ? 152 THR R CA  1 
ATOM 865  C C   . THR A 1 208 ? 143.163 119.504 124.075 1.00 71.20  ? 152 THR R C   1 
ATOM 866  O O   . THR A 1 208 ? 143.213 119.803 125.273 1.00 69.96  ? 152 THR R O   1 
ATOM 867  C CB  . THR A 1 208 ? 143.847 117.152 123.584 1.00 77.29  ? 152 THR R CB  1 
ATOM 868  O OG1 . THR A 1 208 ? 144.447 117.222 122.285 1.00 75.81  ? 152 THR R OG1 1 
ATOM 869  C CG2 . THR A 1 208 ? 143.374 115.733 123.843 1.00 72.28  ? 152 THR R CG2 1 
ATOM 870  N N   . ARG A 1 209 ? 143.521 120.352 123.114 1.00 82.28  ? 153 ARG R N   1 
ATOM 871  C CA  . ARG A 1 209 ? 144.034 121.674 123.431 1.00 84.98  ? 153 ARG R CA  1 
ATOM 872  C C   . ARG A 1 209 ? 142.921 122.566 123.982 1.00 92.00  ? 153 ARG R C   1 
ATOM 873  O O   . ARG A 1 209 ? 141.740 122.208 123.995 1.00 91.33  ? 153 ARG R O   1 
ATOM 874  C CB  . ARG A 1 209 ? 144.663 122.317 122.196 1.00 85.24  ? 153 ARG R CB  1 
ATOM 875  C CG  . ARG A 1 209 ? 145.764 121.491 121.556 1.00 84.64  ? 153 ARG R CG  1 
ATOM 876  C CD  . ARG A 1 209 ? 146.351 122.207 120.348 1.00 86.34  ? 153 ARG R CD  1 
ATOM 877  N NE  . ARG A 1 209 ? 147.670 121.700 119.986 1.00 88.62  ? 153 ARG R NE  1 
ATOM 878  C CZ  . ARG A 1 209 ? 147.898 120.511 119.444 1.00 86.94  ? 153 ARG R CZ  1 
ATOM 879  N NH1 . ARG A 1 209 ? 146.911 119.673 119.172 1.00 84.38  ? 153 ARG R NH1 1 
ATOM 880  N NH2 . ARG A 1 209 ? 149.149 120.155 119.165 1.00 85.24  ? 153 ARG R NH2 1 
ATOM 881  N N   . THR A 1 210 ? 143.318 123.753 124.438 1.00 112.00 ? 154 THR R N   1 
ATOM 882  C CA  . THR A 1 210 ? 142.387 124.708 125.022 1.00 111.56 ? 154 THR R CA  1 
ATOM 883  C C   . THR A 1 210 ? 141.648 125.531 123.976 1.00 108.71 ? 154 THR R C   1 
ATOM 884  O O   . THR A 1 210 ? 140.841 126.390 124.346 1.00 109.09 ? 154 THR R O   1 
ATOM 885  C CB  . THR A 1 210 ? 143.123 125.645 125.983 1.00 109.63 ? 154 THR R CB  1 
ATOM 886  O OG1 . THR A 1 210 ? 144.256 126.219 125.320 1.00 107.72 ? 154 THR R OG1 1 
ATOM 887  C CG2 . THR A 1 210 ? 143.592 124.882 127.212 1.00 108.91 ? 154 THR R CG2 1 
ATOM 888  N N   . LEU A 1 211 ? 141.909 125.298 122.688 1.00 102.07 ? 155 LEU R N   1 
ATOM 889  C CA  . LEU A 1 211 ? 141.177 125.997 121.639 1.00 101.41 ? 155 LEU R CA  1 
ATOM 890  C C   . LEU A 1 211 ? 139.697 125.641 121.643 1.00 103.80 ? 155 LEU R C   1 
ATOM 891  O O   . LEU A 1 211 ? 138.878 126.431 121.160 1.00 104.22 ? 155 LEU R O   1 
ATOM 892  C CB  . LEU A 1 211 ? 141.796 125.683 120.276 1.00 98.22  ? 155 LEU R CB  1 
ATOM 893  C CG  . LEU A 1 211 ? 141.295 126.487 119.075 1.00 100.06 ? 155 LEU R CG  1 
ATOM 894  C CD1 . LEU A 1 211 ? 141.291 127.975 119.392 1.00 103.67 ? 155 LEU R CD1 1 
ATOM 895  C CD2 . LEU A 1 211 ? 142.148 126.200 117.851 1.00 98.79  ? 155 LEU R CD2 1 
ATOM 896  N N   . THR A 1 212 ? 139.335 124.477 122.189 1.00 106.90 ? 156 THR R N   1 
ATOM 897  C CA  . THR A 1 212 ? 137.938 124.066 122.269 1.00 108.72 ? 156 THR R CA  1 
ATOM 898  C C   . THR A 1 212 ? 137.108 124.957 123.185 1.00 110.16 ? 156 THR R C   1 
ATOM 899  O O   . THR A 1 212 ? 135.876 124.893 123.127 1.00 108.61 ? 156 THR R O   1 
ATOM 900  C CB  . THR A 1 212 ? 137.843 122.615 122.746 1.00 106.23 ? 156 THR R CB  1 
ATOM 901  O OG1 . THR A 1 212 ? 136.484 122.171 122.663 1.00 105.98 ? 156 THR R OG1 1 
ATOM 902  C CG2 . THR A 1 212 ? 138.327 122.491 124.183 1.00 105.80 ? 156 THR R CG2 1 
ATOM 903  N N   . GLN A 1 213 ? 137.744 125.777 124.023 1.00 113.70 ? 157 GLN R N   1 
ATOM 904  C CA  . GLN A 1 213 ? 137.013 126.684 124.899 1.00 112.71 ? 157 GLN R CA  1 
ATOM 905  C C   . GLN A 1 213 ? 136.411 127.869 124.156 1.00 115.08 ? 157 GLN R C   1 
ATOM 906  O O   . GLN A 1 213 ? 135.635 128.620 124.754 1.00 115.68 ? 157 GLN R O   1 
ATOM 907  C CB  . GLN A 1 213 ? 137.933 127.196 126.011 1.00 110.98 ? 157 GLN R CB  1 
ATOM 908  C CG  . GLN A 1 213 ? 138.482 126.128 126.952 1.00 112.99 ? 157 GLN R CG  1 
ATOM 909  C CD  . GLN A 1 213 ? 137.406 125.238 127.550 1.00 116.02 ? 157 GLN R CD  1 
ATOM 910  O OE1 . GLN A 1 213 ? 136.944 124.287 126.920 1.00 116.14 ? 157 GLN R OE1 1 
ATOM 911  N NE2 . GLN A 1 213 ? 137.004 125.545 128.778 1.00 115.46 ? 157 GLN R NE2 1 
ATOM 912  N N   . LYS A 1 214 ? 136.748 128.058 122.882 1.00 114.56 ? 158 LYS R N   1 
ATOM 913  C CA  . LYS A 1 214 ? 136.337 129.238 122.131 1.00 113.56 ? 158 LYS R CA  1 
ATOM 914  C C   . LYS A 1 214 ? 135.055 129.039 121.332 1.00 112.21 ? 158 LYS R C   1 
ATOM 915  O O   . LYS A 1 214 ? 134.637 129.965 120.630 1.00 111.88 ? 158 LYS R O   1 
ATOM 916  C CB  . LYS A 1 214 ? 137.462 129.673 121.185 1.00 109.91 ? 158 LYS R CB  1 
ATOM 917  N N   . ARG A 1 215 ? 134.419 127.872 121.417 1.00 103.46 ? 159 ARG R N   1 
ATOM 918  C CA  . ARG A 1 215 ? 133.241 127.573 120.613 1.00 105.14 ? 159 ARG R CA  1 
ATOM 919  C C   . ARG A 1 215 ? 131.933 127.767 121.372 1.00 101.90 ? 159 ARG R C   1 
ATOM 920  O O   . ARG A 1 215 ? 130.877 127.360 120.878 1.00 97.54  ? 159 ARG R O   1 
ATOM 921  C CB  . ARG A 1 215 ? 133.326 126.147 120.061 1.00 104.47 ? 159 ARG R CB  1 
ATOM 922  C CG  . ARG A 1 215 ? 133.096 125.048 121.085 1.00 104.47 ? 159 ARG R CG  1 
ATOM 923  C CD  . ARG A 1 215 ? 133.589 123.711 120.555 1.00 102.91 ? 159 ARG R CD  1 
ATOM 924  N NE  . ARG A 1 215 ? 133.004 122.580 121.266 1.00 103.56 ? 159 ARG R NE  1 
ATOM 925  C CZ  . ARG A 1 215 ? 132.285 121.625 120.690 1.00 101.58 ? 159 ARG R CZ  1 
ATOM 926  N NH1 . ARG A 1 215 ? 132.016 121.649 119.396 1.00 97.57  ? 159 ARG R NH1 1 
ATOM 927  N NH2 . ARG A 1 215 ? 131.823 120.624 121.433 1.00 101.52 ? 159 ARG R NH2 1 
ATOM 928  N N   . TYR A 1 216 ? 131.975 128.386 122.551 1.00 108.73 ? 160 TYR R N   1 
ATOM 929  C CA  . TYR A 1 216 ? 130.783 128.619 123.356 1.00 111.26 ? 160 TYR R CA  1 
ATOM 930  C C   . TYR A 1 216 ? 130.101 129.943 123.024 1.00 111.09 ? 160 TYR R C   1 
ATOM 931  O O   . TYR A 1 216 ? 129.307 130.443 123.829 1.00 111.11 ? 160 TYR R O   1 
ATOM 932  C CB  . TYR A 1 216 ? 131.139 128.567 124.843 1.00 110.69 ? 160 TYR R CB  1 
ATOM 933  C CG  . TYR A 1 216 ? 131.840 127.291 125.249 1.00 111.94 ? 160 TYR R CG  1 
ATOM 934  C CD1 . TYR A 1 216 ? 131.295 126.050 124.949 1.00 111.21 ? 160 TYR R CD1 1 
ATOM 935  C CD2 . TYR A 1 216 ? 133.050 127.328 125.929 1.00 111.20 ? 160 TYR R CD2 1 
ATOM 936  C CE1 . TYR A 1 216 ? 131.935 124.882 125.315 1.00 111.72 ? 160 TYR R CE1 1 
ATOM 937  C CE2 . TYR A 1 216 ? 133.697 126.166 126.300 1.00 110.00 ? 160 TYR R CE2 1 
ATOM 938  C CZ  . TYR A 1 216 ? 133.135 124.946 125.990 1.00 112.18 ? 160 TYR R CZ  1 
ATOM 939  O OH  . TYR A 1 216 ? 133.775 123.784 126.357 1.00 114.86 ? 160 TYR R OH  1 
ATOM 940  N N   . LEU A 1 217 ? 130.390 130.515 121.855 1.00 105.31 ? 161 LEU R N   1 
ATOM 941  C CA  . LEU A 1 217 ? 129.874 131.813 121.439 1.00 104.59 ? 161 LEU R CA  1 
ATOM 942  C C   . LEU A 1 217 ? 128.821 131.686 120.337 1.00 103.94 ? 161 LEU R C   1 
ATOM 943  O O   . LEU A 1 217 ? 128.639 132.596 119.528 1.00 101.47 ? 161 LEU R O   1 
ATOM 944  C CB  . LEU A 1 217 ? 131.048 132.709 121.028 1.00 106.30 ? 161 LEU R CB  1 
ATOM 945  C CG  . LEU A 1 217 ? 131.824 132.624 119.700 1.00 105.09 ? 161 LEU R CG  1 
ATOM 946  C CD1 . LEU A 1 217 ? 131.266 133.490 118.576 1.00 103.15 ? 161 LEU R CD1 1 
ATOM 947  C CD2 . LEU A 1 217 ? 133.293 132.950 119.942 1.00 102.61 ? 161 LEU R CD2 1 
ATOM 948  N N   . VAL A 1 218 ? 128.069 130.581 120.347 1.00 99.76  ? 162 VAL R N   1 
ATOM 949  C CA  . VAL A 1 218 ? 127.196 130.249 119.223 1.00 98.98  ? 162 VAL R CA  1 
ATOM 950  C C   . VAL A 1 218 ? 126.141 131.326 119.004 1.00 101.74 ? 162 VAL R C   1 
ATOM 951  O O   . VAL A 1 218 ? 125.778 131.629 117.862 1.00 99.55  ? 162 VAL R O   1 
ATOM 952  C CB  . VAL A 1 218 ? 126.557 128.864 119.432 1.00 97.04  ? 162 VAL R CB  1 
ATOM 953  C CG1 . VAL A 1 218 ? 127.607 127.791 119.279 1.00 99.78  ? 162 VAL R CG1 1 
ATOM 954  C CG2 . VAL A 1 218 ? 125.896 128.776 120.798 1.00 97.89  ? 162 VAL R CG2 1 
ATOM 955  N N   . LYS A 1 219 ? 125.621 131.914 120.084 1.00 107.02 ? 163 LYS R N   1 
ATOM 956  C CA  . LYS A 1 219 ? 124.625 132.970 119.926 1.00 105.71 ? 163 LYS R CA  1 
ATOM 957  C C   . LYS A 1 219 ? 125.212 134.176 119.203 1.00 104.74 ? 163 LYS R C   1 
ATOM 958  O O   . LYS A 1 219 ? 124.580 134.741 118.301 1.00 101.50 ? 163 LYS R O   1 
ATOM 959  C CB  . LYS A 1 219 ? 124.071 133.377 121.291 1.00 102.19 ? 163 LYS R CB  1 
ATOM 960  N N   . PHE A 1 220 ? 126.432 134.571 119.573 1.00 104.74 ? 164 PHE R N   1 
ATOM 961  C CA  . PHE A 1 220 ? 127.063 135.734 118.956 1.00 103.25 ? 164 PHE R CA  1 
ATOM 962  C C   . PHE A 1 220 ? 127.328 135.493 117.475 1.00 103.04 ? 164 PHE R C   1 
ATOM 963  O O   . PHE A 1 220 ? 127.033 136.348 116.631 1.00 98.86  ? 164 PHE R O   1 
ATOM 964  C CB  . PHE A 1 220 ? 128.366 136.078 119.684 1.00 101.31 ? 164 PHE R CB  1 
ATOM 965  C CG  . PHE A 1 220 ? 128.181 136.561 121.105 1.00 102.68 ? 164 PHE R CG  1 
ATOM 966  C CD1 . PHE A 1 220 ? 129.252 137.101 121.799 1.00 103.14 ? 164 PHE R CD1 1 
ATOM 967  C CD2 . PHE A 1 220 ? 126.948 136.499 121.738 1.00 101.44 ? 164 PHE R CD2 1 
ATOM 968  C CE1 . PHE A 1 220 ? 129.102 137.551 123.096 1.00 103.12 ? 164 PHE R CE1 1 
ATOM 969  C CE2 . PHE A 1 220 ? 126.792 136.948 123.035 1.00 99.34  ? 164 PHE R CE2 1 
ATOM 970  C CZ  . PHE A 1 220 ? 127.870 137.476 123.714 1.00 102.06 ? 164 PHE R CZ  1 
ATOM 971  N N   . ILE A 1 221 ? 127.887 134.327 117.139 1.00 102.03 ? 165 ILE R N   1 
ATOM 972  C CA  . ILE A 1 221 ? 128.195 134.038 115.742 1.00 100.22 ? 165 ILE R CA  1 
ATOM 973  C C   . ILE A 1 221 ? 126.916 133.869 114.932 1.00 98.51  ? 165 ILE R C   1 
ATOM 974  O O   . ILE A 1 221 ? 126.869 134.247 113.758 1.00 97.35  ? 165 ILE R O   1 
ATOM 975  C CB  . ILE A 1 221 ? 129.120 132.810 115.623 1.00 97.37  ? 165 ILE R CB  1 
ATOM 976  C CG1 . ILE A 1 221 ? 129.629 132.661 114.187 1.00 94.65  ? 165 ILE R CG1 1 
ATOM 977  C CG2 . ILE A 1 221 ? 128.420 131.541 116.074 1.00 94.14  ? 165 ILE R CG2 1 
ATOM 978  C CD1 . ILE A 1 221 ? 130.924 131.888 114.076 1.00 94.32  ? 165 ILE R CD1 1 
ATOM 979  N N   . CYS A 1 222 ? 125.859 133.318 115.534 1.00 96.50  ? 166 CYS R N   1 
ATOM 980  C CA  . CYS A 1 222 ? 124.586 133.217 114.829 1.00 98.98  ? 166 CYS R CA  1 
ATOM 981  C C   . CYS A 1 222 ? 124.010 134.596 114.532 1.00 98.64  ? 166 CYS R C   1 
ATOM 982  O O   . CYS A 1 222 ? 123.538 134.851 113.417 1.00 91.46  ? 166 CYS R O   1 
ATOM 983  C CB  . CYS A 1 222 ? 123.598 132.384 115.645 1.00 91.95  ? 166 CYS R CB  1 
ATOM 984  S SG  . CYS A 1 222 ? 123.855 130.601 115.526 1.00 85.94  ? 166 CYS R SG  1 
ATOM 985  N N   . LEU A 1 223 ? 124.047 135.501 115.514 1.00 102.11 ? 167 LEU R N   1 
ATOM 986  C CA  . LEU A 1 223 ? 123.575 136.860 115.273 1.00 100.09 ? 167 LEU R CA  1 
ATOM 987  C C   . LEU A 1 223 ? 124.404 137.541 114.192 1.00 99.14  ? 167 LEU R C   1 
ATOM 988  O O   . LEU A 1 223 ? 123.860 138.231 113.321 1.00 102.48 ? 167 LEU R O   1 
ATOM 989  C CB  . LEU A 1 223 ? 123.611 137.668 116.570 1.00 99.10  ? 167 LEU R CB  1 
ATOM 990  N N   . SER A 1 224 ? 125.725 137.347 114.226 1.00 93.89  ? 168 SER R N   1 
ATOM 991  C CA  . SER A 1 224 ? 126.586 137.920 113.197 1.00 97.87  ? 168 SER R CA  1 
ATOM 992  C C   . SER A 1 224 ? 126.243 137.367 111.820 1.00 95.90  ? 168 SER R C   1 
ATOM 993  O O   . SER A 1 224 ? 126.230 138.109 110.832 1.00 94.51  ? 168 SER R O   1 
ATOM 994  C CB  . SER A 1 224 ? 128.053 137.652 113.533 1.00 96.12  ? 168 SER R CB  1 
ATOM 995  O OG  . SER A 1 224 ? 128.898 138.029 112.460 1.00 96.35  ? 168 SER R OG  1 
ATOM 996  N N   . ILE A 1 225 ? 125.966 136.065 111.735 1.00 92.06  ? 169 ILE R N   1 
ATOM 997  C CA  . ILE A 1 225 ? 125.644 135.449 110.451 1.00 93.78  ? 169 ILE R CA  1 
ATOM 998  C C   . ILE A 1 225 ? 124.330 135.998 109.909 1.00 95.66  ? 169 ILE R C   1 
ATOM 999  O O   . ILE A 1 225 ? 124.225 136.341 108.725 1.00 94.01  ? 169 ILE R O   1 
ATOM 1000 C CB  . ILE A 1 225 ? 125.605 133.916 110.587 1.00 90.93  ? 169 ILE R CB  1 
ATOM 1001 C CG1 . ILE A 1 225 ? 127.024 133.361 110.713 1.00 89.00  ? 169 ILE R CG1 1 
ATOM 1002 C CG2 . ILE A 1 225 ? 124.888 133.290 109.404 1.00 90.47  ? 169 ILE R CG2 1 
ATOM 1003 C CD1 . ILE A 1 225 ? 127.903 133.660 109.521 1.00 86.87  ? 169 ILE R CD1 1 
ATOM 1004 N N   . TRP A 1 226 ? 123.309 136.094 110.767 1.00 90.98  ? 170 TRP R N   1 
ATOM 1005 C CA  . TRP A 1 226 ? 122.035 136.657 110.326 1.00 89.38  ? 170 TRP R CA  1 
ATOM 1006 C C   . TRP A 1 226 ? 122.201 138.101 109.868 1.00 85.76  ? 170 TRP R C   1 
ATOM 1007 O O   . TRP A 1 226 ? 121.652 138.501 108.831 1.00 80.35  ? 170 TRP R O   1 
ATOM 1008 C CB  . TRP A 1 226 ? 120.990 136.565 111.441 1.00 87.47  ? 170 TRP R CB  1 
ATOM 1009 C CG  . TRP A 1 226 ? 120.495 135.170 111.727 1.00 85.22  ? 170 TRP R CG  1 
ATOM 1010 C CD1 . TRP A 1 226 ? 120.803 134.397 112.807 1.00 81.99  ? 170 TRP R CD1 1 
ATOM 1011 C CD2 . TRP A 1 226 ? 119.588 134.398 110.930 1.00 85.65  ? 170 TRP R CD2 1 
ATOM 1012 N NE1 . TRP A 1 226 ? 120.158 133.189 112.727 1.00 83.02  ? 170 TRP R NE1 1 
ATOM 1013 C CE2 . TRP A 1 226 ? 119.403 133.165 111.585 1.00 84.79  ? 170 TRP R CE2 1 
ATOM 1014 C CE3 . TRP A 1 226 ? 118.918 134.628 109.725 1.00 86.34  ? 170 TRP R CE3 1 
ATOM 1015 C CZ2 . TRP A 1 226 ? 118.578 132.166 111.075 1.00 84.97  ? 170 TRP R CZ2 1 
ATOM 1016 C CZ3 . TRP A 1 226 ? 118.100 133.635 109.221 1.00 84.00  ? 170 TRP R CZ3 1 
ATOM 1017 C CH2 . TRP A 1 226 ? 117.937 132.419 109.895 1.00 84.87  ? 170 TRP R CH2 1 
ATOM 1018 N N   . GLY A 1 227 ? 122.969 138.896 110.617 1.00 95.28  ? 171 GLY R N   1 
ATOM 1019 C CA  . GLY A 1 227 ? 123.178 140.282 110.230 1.00 95.91  ? 171 GLY R CA  1 
ATOM 1020 C C   . GLY A 1 227 ? 123.921 140.421 108.915 1.00 97.20  ? 171 GLY R C   1 
ATOM 1021 O O   . GLY A 1 227 ? 123.558 141.245 108.071 1.00 100.91 ? 171 GLY R O   1 
ATOM 1022 N N   . LEU A 1 228 ? 124.972 139.621 108.723 1.00 91.50  ? 172 LEU R N   1 
ATOM 1023 C CA  . LEU A 1 228 ? 125.733 139.692 107.480 1.00 93.12  ? 172 LEU R CA  1 
ATOM 1024 C C   . LEU A 1 228 ? 124.895 139.225 106.298 1.00 92.44  ? 172 LEU R C   1 
ATOM 1025 O O   . LEU A 1 228 ? 124.990 139.791 105.203 1.00 92.17  ? 172 LEU R O   1 
ATOM 1026 C CB  . LEU A 1 228 ? 127.015 138.868 107.598 1.00 94.32  ? 172 LEU R CB  1 
ATOM 1027 C CG  . LEU A 1 228 ? 127.899 138.814 106.350 1.00 93.26  ? 172 LEU R CG  1 
ATOM 1028 C CD1 . LEU A 1 228 ? 128.477 140.185 106.045 1.00 89.98  ? 172 LEU R CD1 1 
ATOM 1029 C CD2 . LEU A 1 228 ? 129.011 137.792 106.523 1.00 95.01  ? 172 LEU R CD2 1 
ATOM 1030 N N   . SER A 1 229 ? 124.064 138.199 106.499 1.00 87.77  ? 173 SER R N   1 
ATOM 1031 C CA  . SER A 1 229 ? 123.163 137.762 105.439 1.00 92.24  ? 173 SER R CA  1 
ATOM 1032 C C   . SER A 1 229 ? 122.174 138.859 105.066 1.00 94.98  ? 173 SER R C   1 
ATOM 1033 O O   . SER A 1 229 ? 121.935 139.116 103.878 1.00 88.22  ? 173 SER R O   1 
ATOM 1034 C CB  . SER A 1 229 ? 122.423 136.500 105.878 1.00 90.68  ? 173 SER R CB  1 
ATOM 1035 O OG  . SER A 1 229 ? 121.304 136.250 105.049 1.00 91.46  ? 173 SER R OG  1 
ATOM 1036 N N   . LEU A 1 230 ? 121.594 139.524 106.070 1.00 103.18 ? 174 LEU R N   1 
ATOM 1037 C CA  . LEU A 1 230 ? 120.673 140.621 105.789 1.00 98.84  ? 174 LEU R CA  1 
ATOM 1038 C C   . LEU A 1 230 ? 121.373 141.750 105.042 1.00 97.35  ? 174 LEU R C   1 
ATOM 1039 O O   . LEU A 1 230 ? 120.823 142.307 104.084 1.00 95.76  ? 174 LEU R O   1 
ATOM 1040 C CB  . LEU A 1 230 ? 120.059 141.137 107.090 1.00 97.68  ? 174 LEU R CB  1 
ATOM 1041 N N   . LEU A 1 231 ? 122.590 142.100 105.466 1.00 101.34 ? 175 LEU R N   1 
ATOM 1042 C CA  . LEU A 1 231 ? 123.331 143.161 104.791 1.00 102.48 ? 175 LEU R CA  1 
ATOM 1043 C C   . LEU A 1 231 ? 123.636 142.788 103.346 1.00 102.90 ? 175 LEU R C   1 
ATOM 1044 O O   . LEU A 1 231 ? 123.511 143.621 102.441 1.00 104.46 ? 175 LEU R O   1 
ATOM 1045 C CB  . LEU A 1 231 ? 124.623 143.465 105.548 1.00 99.26  ? 175 LEU R CB  1 
ATOM 1046 C CG  . LEU A 1 231 ? 125.613 144.374 104.818 1.00 100.80 ? 175 LEU R CG  1 
ATOM 1047 C CD1 . LEU A 1 231 ? 125.082 145.796 104.754 1.00 101.86 ? 175 LEU R CD1 1 
ATOM 1048 C CD2 . LEU A 1 231 ? 126.981 144.337 105.480 1.00 103.08 ? 175 LEU R CD2 1 
ATOM 1049 N N   . LEU A 1 232 ? 124.036 141.537 103.109 1.00 98.16  ? 176 LEU R N   1 
ATOM 1050 C CA  . LEU A 1 232 ? 124.365 141.108 101.756 1.00 99.34  ? 176 LEU R CA  1 
ATOM 1051 C C   . LEU A 1 232 ? 123.129 141.033 100.868 1.00 102.75 ? 176 LEU R C   1 
ATOM 1052 O O   . LEU A 1 232 ? 123.232 141.223 99.651  1.00 101.09 ? 176 LEU R O   1 
ATOM 1053 C CB  . LEU A 1 232 ? 125.080 139.758 101.798 1.00 97.85  ? 176 LEU R CB  1 
ATOM 1054 C CG  . LEU A 1 232 ? 126.521 139.788 102.310 1.00 97.20  ? 176 LEU R CG  1 
ATOM 1055 C CD1 . LEU A 1 232 ? 127.174 138.422 102.179 1.00 96.28  ? 176 LEU R CD1 1 
ATOM 1056 C CD2 . LEU A 1 232 ? 127.322 140.837 101.561 1.00 99.81  ? 176 LEU R CD2 1 
ATOM 1057 N N   . ALA A 1 233 ? 121.961 140.757 101.447 1.00 101.44 ? 177 ALA R N   1 
ATOM 1058 C CA  . ALA A 1 233 ? 120.733 140.688 100.665 1.00 100.99 ? 177 ALA R CA  1 
ATOM 1059 C C   . ALA A 1 233 ? 119.993 142.017 100.581 1.00 101.78 ? 177 ALA R C   1 
ATOM 1060 O O   . ALA A 1 233 ? 118.982 142.098 99.876  1.00 99.60  ? 177 ALA R O   1 
ATOM 1061 C CB  . ALA A 1 233 ? 119.800 139.622 101.243 1.00 102.71 ? 177 ALA R CB  1 
ATOM 1062 N N   . LEU A 1 234 ? 120.453 143.045 101.293 1.00 103.42 ? 178 LEU R N   1 
ATOM 1063 C CA  . LEU A 1 234 ? 119.844 144.370 101.177 1.00 104.45 ? 178 LEU R CA  1 
ATOM 1064 C C   . LEU A 1 234 ? 119.761 144.903 99.747  1.00 105.29 ? 178 LEU R C   1 
ATOM 1065 O O   . LEU A 1 234 ? 118.738 145.528 99.417  1.00 104.67 ? 178 LEU R O   1 
ATOM 1066 C CB  . LEU A 1 234 ? 120.594 145.366 102.074 1.00 101.83 ? 178 LEU R CB  1 
ATOM 1067 C CG  . LEU A 1 234 ? 120.094 145.470 103.515 1.00 101.54 ? 178 LEU R CG  1 
ATOM 1068 C CD1 . LEU A 1 234 ? 120.937 146.453 104.311 1.00 100.92 ? 178 LEU R CD1 1 
ATOM 1069 C CD2 . LEU A 1 234 ? 118.629 145.872 103.543 1.00 99.42  ? 178 LEU R CD2 1 
ATOM 1070 N N   . PRO A 1 235 ? 120.766 144.736 98.876  1.00 105.62 ? 179 PRO R N   1 
ATOM 1071 C CA  . PRO A 1 235 ? 120.589 145.186 97.486  1.00 103.34 ? 179 PRO R CA  1 
ATOM 1072 C C   . PRO A 1 235 ? 119.393 144.556 96.799  1.00 104.94 ? 179 PRO R C   1 
ATOM 1073 O O   . PRO A 1 235 ? 118.810 145.172 95.898  1.00 106.41 ? 179 PRO R O   1 
ATOM 1074 C CB  . PRO A 1 235 ? 121.904 144.770 96.818  1.00 105.10 ? 179 PRO R CB  1 
ATOM 1075 C CG  . PRO A 1 235 ? 122.895 144.828 97.909  1.00 105.45 ? 179 PRO R CG  1 
ATOM 1076 C CD  . PRO A 1 235 ? 122.165 144.343 99.134  1.00 105.04 ? 179 PRO R CD  1 
ATOM 1077 N N   . VAL A 1 236 ? 119.014 143.338 97.190  1.00 111.25 ? 180 VAL R N   1 
ATOM 1078 C CA  . VAL A 1 236 ? 117.802 142.727 96.651  1.00 113.21 ? 180 VAL R CA  1 
ATOM 1079 C C   . VAL A 1 236 ? 116.575 143.536 97.057  1.00 111.72 ? 180 VAL R C   1 
ATOM 1080 O O   . VAL A 1 236 ? 115.697 143.821 96.236  1.00 111.53 ? 180 VAL R O   1 
ATOM 1081 C CB  . VAL A 1 236 ? 117.696 141.261 97.108  1.00 112.23 ? 180 VAL R CB  1 
ATOM 1082 C CG1 . VAL A 1 236 ? 116.267 140.780 97.015  1.00 109.61 ? 180 VAL R CG1 1 
ATOM 1083 C CG2 . VAL A 1 236 ? 118.610 140.380 96.270  1.00 111.62 ? 180 VAL R CG2 1 
ATOM 1084 N N   . LEU A 1 237 ? 116.500 143.927 98.330  1.00 111.85 ? 181 LEU R N   1 
ATOM 1085 C CA  . LEU A 1 237 ? 115.363 144.724 98.779  1.00 112.00 ? 181 LEU R CA  1 
ATOM 1086 C C   . LEU A 1 237 ? 115.336 146.085 98.095  1.00 113.08 ? 181 LEU R C   1 
ATOM 1087 O O   . LEU A 1 237 ? 114.268 146.575 97.709  1.00 110.95 ? 181 LEU R O   1 
ATOM 1088 C CB  . LEU A 1 237 ? 115.404 144.888 100.298 1.00 113.25 ? 181 LEU R CB  1 
ATOM 1089 C CG  . LEU A 1 237 ? 114.665 146.099 100.870 1.00 112.16 ? 181 LEU R CG  1 
ATOM 1090 C CD1 . LEU A 1 237 ? 113.178 145.807 101.002 1.00 110.84 ? 181 LEU R CD1 1 
ATOM 1091 C CD2 . LEU A 1 237 ? 115.255 146.507 102.209 1.00 112.91 ? 181 LEU R CD2 1 
ATOM 1092 N N   . LEU A 1 238 ? 116.503 146.709 97.931  1.00 114.59 ? 182 LEU R N   1 
ATOM 1093 C CA  . LEU A 1 238 ? 116.544 148.085 97.444  1.00 113.29 ? 182 LEU R CA  1 
ATOM 1094 C C   . LEU A 1 238 ? 116.317 148.187 95.936  1.00 111.28 ? 182 LEU R C   1 
ATOM 1095 O O   . LEU A 1 238 ? 115.655 149.124 95.476  1.00 111.03 ? 182 LEU R O   1 
ATOM 1096 C CB  . LEU A 1 238 ? 117.876 148.731 97.825  1.00 112.90 ? 182 LEU R CB  1 
ATOM 1097 C CG  . LEU A 1 238 ? 118.173 148.856 99.319  1.00 111.97 ? 182 LEU R CG  1 
ATOM 1098 C CD1 . LEU A 1 238 ? 119.586 149.371 99.539  1.00 112.09 ? 182 LEU R CD1 1 
ATOM 1099 C CD2 . LEU A 1 238 ? 117.155 149.765 99.988  1.00 111.27 ? 182 LEU R CD2 1 
ATOM 1100 N N   . PHE A 1 239 ? 116.847 147.251 95.150  1.00 111.72 ? 183 PHE R N   1 
ATOM 1101 C CA  . PHE A 1 239 ? 116.852 147.368 93.690  1.00 111.35 ? 183 PHE R CA  1 
ATOM 1102 C C   . PHE A 1 239 ? 116.170 146.171 93.031  1.00 112.45 ? 183 PHE R C   1 
ATOM 1103 O O   . PHE A 1 239 ? 116.718 145.538 92.127  1.00 112.66 ? 183 PHE R O   1 
ATOM 1104 C CB  . PHE A 1 239 ? 118.264 147.515 93.122  1.00 112.52 ? 183 PHE R CB  1 
ATOM 1105 C CG  . PHE A 1 239 ? 119.253 148.145 94.064  1.00 112.33 ? 183 PHE R CG  1 
ATOM 1106 C CD1 . PHE A 1 239 ? 119.043 149.418 94.570  1.00 112.35 ? 183 PHE R CD1 1 
ATOM 1107 C CD2 . PHE A 1 239 ? 120.402 147.466 94.433  1.00 112.22 ? 183 PHE R CD2 1 
ATOM 1108 C CE1 . PHE A 1 239 ? 119.960 149.999 95.428  1.00 112.72 ? 183 PHE R CE1 1 
ATOM 1109 C CE2 . PHE A 1 239 ? 121.318 148.040 95.294  1.00 113.17 ? 183 PHE R CE2 1 
ATOM 1110 C CZ  . PHE A 1 239 ? 121.096 149.307 95.793  1.00 113.08 ? 183 PHE R CZ  1 
ATOM 1111 N N   . ARG A 1 240 ? 114.958 145.842 93.471  1.00 113.73 ? 184 ARG R N   1 
ATOM 1112 C CA  . ARG A 1 240 ? 114.136 144.846 92.792  1.00 113.92 ? 184 ARG R CA  1 
ATOM 1113 C C   . ARG A 1 240 ? 112.724 145.383 92.628  1.00 113.77 ? 184 ARG R C   1 
ATOM 1114 O O   . ARG A 1 240 ? 112.125 145.872 93.591  1.00 113.73 ? 184 ARG R O   1 
ATOM 1115 C CB  . ARG A 1 240 ? 114.114 143.516 93.552  1.00 114.69 ? 184 ARG R CB  1 
ATOM 1116 C CG  . ARG A 1 240 ? 115.402 142.715 93.433  1.00 115.32 ? 184 ARG R CG  1 
ATOM 1117 C CD  . ARG A 1 240 ? 115.414 141.832 92.198  1.00 114.81 ? 184 ARG R CD  1 
ATOM 1118 N NE  . ARG A 1 240 ? 116.581 140.956 92.168  1.00 114.40 ? 184 ARG R NE  1 
ATOM 1119 C CZ  . ARG A 1 240 ? 116.792 139.946 93.001  1.00 113.81 ? 184 ARG R CZ  1 
ATOM 1120 N NH1 . ARG A 1 240 ? 115.912 139.619 93.932  1.00 113.24 ? 184 ARG R NH1 1 
ATOM 1121 N NH2 . ARG A 1 240 ? 117.914 139.240 92.891  1.00 113.57 ? 184 ARG R NH2 1 
ATOM 1122 N N   . ARG A 1 241 ? 112.196 145.288 91.410  1.00 119.07 ? 185 ARG R N   1 
ATOM 1123 C CA  . ARG A 1 241 ? 110.855 145.763 91.108  1.00 120.52 ? 185 ARG R CA  1 
ATOM 1124 C C   . ARG A 1 241 ? 110.318 144.997 89.909  1.00 120.76 ? 185 ARG R C   1 
ATOM 1125 O O   . ARG A 1 241 ? 111.073 144.386 89.148  1.00 121.12 ? 185 ARG R O   1 
ATOM 1126 C CB  . ARG A 1 241 ? 110.839 147.271 90.829  1.00 120.48 ? 185 ARG R CB  1 
ATOM 1127 C CG  . ARG A 1 241 ? 111.132 147.628 89.381  1.00 118.33 ? 185 ARG R CG  1 
ATOM 1128 C CD  . ARG A 1 241 ? 111.019 149.121 89.136  1.00 118.82 ? 185 ARG R CD  1 
ATOM 1129 N NE  . ARG A 1 241 ? 110.706 149.414 87.742  1.00 119.25 ? 185 ARG R NE  1 
ATOM 1130 C CZ  . ARG A 1 241 ? 110.579 150.636 87.243  1.00 119.05 ? 185 ARG R CZ  1 
ATOM 1131 N NH1 . ARG A 1 241 ? 110.734 151.711 87.998  1.00 119.19 ? 185 ARG R NH1 1 
ATOM 1132 N NH2 . ARG A 1 241 ? 110.290 150.782 85.953  1.00 118.75 ? 185 ARG R NH2 1 
ATOM 1133 N N   . THR A 1 242 ? 108.997 145.033 89.750  1.00 117.30 ? 186 THR R N   1 
ATOM 1134 C CA  . THR A 1 242 ? 108.368 144.388 88.606  1.00 117.00 ? 186 THR R CA  1 
ATOM 1135 C C   . THR A 1 242 ? 108.742 145.120 87.324  1.00 118.82 ? 186 THR R C   1 
ATOM 1136 O O   . THR A 1 242 ? 108.680 146.352 87.258  1.00 120.36 ? 186 THR R O   1 
ATOM 1137 C CB  . THR A 1 242 ? 106.851 144.360 88.776  1.00 116.49 ? 186 THR R CB  1 
ATOM 1138 O OG1 . THR A 1 242 ? 106.346 145.700 88.795  1.00 119.41 ? 186 THR R OG1 1 
ATOM 1139 C CG2 . THR A 1 242 ? 106.475 143.668 90.076  1.00 116.58 ? 186 THR R CG2 1 
ATOM 1140 N N   . VAL A 1 243 ? 109.135 144.361 86.304  1.00 118.81 ? 187 VAL R N   1 
ATOM 1141 C CA  . VAL A 1 243 ? 109.539 144.907 85.014  1.00 118.82 ? 187 VAL R CA  1 
ATOM 1142 C C   . VAL A 1 243 ? 108.619 144.341 83.944  1.00 118.89 ? 187 VAL R C   1 
ATOM 1143 O O   . VAL A 1 243 ? 108.405 143.125 83.880  1.00 119.13 ? 187 VAL R O   1 
ATOM 1144 C CB  . VAL A 1 243 ? 111.011 144.593 84.694  1.00 118.67 ? 187 VAL R CB  1 
ATOM 1145 C CG1 . VAL A 1 243 ? 111.485 145.429 83.518  1.00 119.71 ? 187 VAL R CG1 1 
ATOM 1146 C CG2 . VAL A 1 243 ? 111.880 144.860 85.908  1.00 118.07 ? 187 VAL R CG2 1 
ATOM 1147 N N   . TYR A 1 244 ? 108.082 145.221 83.106  1.00 123.40 ? 188 TYR R N   1 
ATOM 1148 C CA  . TYR A 1 244 ? 107.124 144.849 82.078  1.00 125.27 ? 188 TYR R CA  1 
ATOM 1149 C C   . TYR A 1 244 ? 107.789 144.832 80.707  1.00 126.02 ? 188 TYR R C   1 
ATOM 1150 O O   . TYR A 1 244 ? 108.719 145.596 80.435  1.00 125.95 ? 188 TYR R O   1 
ATOM 1151 C CB  . TYR A 1 244 ? 105.940 145.819 82.067  1.00 124.08 ? 188 TYR R CB  1 
ATOM 1152 C CG  . TYR A 1 244 ? 104.968 145.612 83.205  1.00 124.88 ? 188 TYR R CG  1 
ATOM 1153 C CD1 . TYR A 1 244 ? 104.260 144.425 83.333  1.00 123.86 ? 188 TYR R CD1 1 
ATOM 1154 C CD2 . TYR A 1 244 ? 104.764 146.602 84.157  1.00 125.33 ? 188 TYR R CD2 1 
ATOM 1155 C CE1 . TYR A 1 244 ? 103.371 144.232 84.374  1.00 124.54 ? 188 TYR R CE1 1 
ATOM 1156 C CE2 . TYR A 1 244 ? 103.879 146.419 85.202  1.00 125.41 ? 188 TYR R CE2 1 
ATOM 1157 C CZ  . TYR A 1 244 ? 103.185 145.232 85.306  1.00 126.12 ? 188 TYR R CZ  1 
ATOM 1158 O OH  . TYR A 1 244 ? 102.302 145.043 86.344  1.00 125.51 ? 188 TYR R OH  1 
ATOM 1159 N N   . SER A 1 245 ? 107.301 143.943 79.844  1.00 122.40 ? 189 SER R N   1 
ATOM 1160 C CA  . SER A 1 245 ? 107.787 143.845 78.476  1.00 121.18 ? 189 SER R CA  1 
ATOM 1161 C C   . SER A 1 245 ? 106.669 143.305 77.598  1.00 121.59 ? 189 SER R C   1 
ATOM 1162 O O   . SER A 1 245 ? 105.789 142.578 78.067  1.00 121.95 ? 189 SER R O   1 
ATOM 1163 C CB  . SER A 1 245 ? 109.028 142.950 78.377  1.00 121.08 ? 189 SER R CB  1 
ATOM 1164 O OG  . SER A 1 245 ? 110.084 143.451 79.176  1.00 120.31 ? 189 SER R OG  1 
ATOM 1165 N N   . SER A 1 246 ? 106.711 143.672 76.315  1.00 120.46 ? 190 SER R N   1 
ATOM 1166 C CA  . SER A 1 246 ? 105.657 143.258 75.394  1.00 119.13 ? 190 SER R CA  1 
ATOM 1167 C C   . SER A 1 246 ? 105.680 141.753 75.154  1.00 117.99 ? 190 SER R C   1 
ATOM 1168 O O   . SER A 1 246 ? 104.628 141.105 75.148  1.00 118.68 ? 190 SER R O   1 
ATOM 1169 C CB  . SER A 1 246 ? 105.791 144.012 74.071  1.00 119.18 ? 190 SER R CB  1 
ATOM 1170 O OG  . SER A 1 246 ? 105.626 145.407 74.259  1.00 120.79 ? 190 SER R OG  1 
ATOM 1171 N N   . ASN A 1 247 ? 106.867 141.181 74.957  1.00 115.31 ? 191 ASN R N   1 
ATOM 1172 C CA  . ASN A 1 247 ? 107.000 139.770 74.619  1.00 115.27 ? 191 ASN R CA  1 
ATOM 1173 C C   . ASN A 1 247 ? 107.340 138.887 75.812  1.00 116.35 ? 191 ASN R C   1 
ATOM 1174 O O   . ASN A 1 247 ? 107.319 137.660 75.676  1.00 115.75 ? 191 ASN R O   1 
ATOM 1175 C CB  . ASN A 1 247 ? 108.068 139.587 73.534  1.00 116.58 ? 191 ASN R CB  1 
ATOM 1176 C CG  . ASN A 1 247 ? 109.277 140.477 73.751  1.00 117.45 ? 191 ASN R CG  1 
ATOM 1177 O OD1 . ASN A 1 247 ? 109.582 140.865 74.878  1.00 117.86 ? 191 ASN R OD1 1 
ATOM 1178 N ND2 . ASN A 1 247 ? 109.974 140.802 72.668  1.00 116.64 ? 191 ASN R ND2 1 
ATOM 1179 N N   . VAL A 1 248 ? 107.648 139.470 76.967  1.00 113.75 ? 192 VAL R N   1 
ATOM 1180 C CA  . VAL A 1 248 ? 108.042 138.718 78.153  1.00 113.85 ? 192 VAL R CA  1 
ATOM 1181 C C   . VAL A 1 248 ? 107.019 138.973 79.249  1.00 114.19 ? 192 VAL R C   1 
ATOM 1182 O O   . VAL A 1 248 ? 106.646 140.124 79.503  1.00 112.86 ? 192 VAL R O   1 
ATOM 1183 C CB  . VAL A 1 248 ? 109.456 139.099 78.628  1.00 112.97 ? 192 VAL R CB  1 
ATOM 1184 C CG1 . VAL A 1 248 ? 109.915 138.158 79.731  1.00 112.66 ? 192 VAL R CG1 1 
ATOM 1185 C CG2 . VAL A 1 248 ? 110.434 139.077 77.465  1.00 112.02 ? 192 VAL R CG2 1 
ATOM 1186 N N   . SER A 1 249 ? 106.565 137.899 79.891  1.00 117.59 ? 193 SER R N   1 
ATOM 1187 C CA  . SER A 1 249 ? 105.664 138.029 81.022  1.00 116.19 ? 193 SER R CA  1 
ATOM 1188 C C   . SER A 1 249 ? 106.369 138.763 82.162  1.00 117.26 ? 193 SER R C   1 
ATOM 1189 O O   . SER A 1 249 ? 107.588 138.649 82.322  1.00 119.70 ? 193 SER R O   1 
ATOM 1190 C CB  . SER A 1 249 ? 105.195 136.650 81.485  1.00 114.85 ? 193 SER R CB  1 
ATOM 1191 O OG  . SER A 1 249 ? 106.270 135.902 82.025  1.00 114.03 ? 193 SER R OG  1 
ATOM 1192 N N   . PRO A 1 250 ? 105.634 139.533 82.964  1.00 114.75 ? 194 PRO R N   1 
ATOM 1193 C CA  . PRO A 1 250 ? 106.283 140.301 84.031  1.00 114.52 ? 194 PRO R CA  1 
ATOM 1194 C C   . PRO A 1 250 ? 106.857 139.394 85.107  1.00 113.52 ? 194 PRO R C   1 
ATOM 1195 O O   . PRO A 1 250 ? 106.325 138.322 85.402  1.00 113.87 ? 194 PRO R O   1 
ATOM 1196 C CB  . PRO A 1 250 ? 105.154 141.181 84.586  1.00 115.62 ? 194 PRO R CB  1 
ATOM 1197 C CG  . PRO A 1 250 ? 103.896 140.775 83.857  1.00 114.05 ? 194 PRO R CG  1 
ATOM 1198 C CD  . PRO A 1 250 ? 104.172 139.515 83.115  1.00 114.31 ? 194 PRO R CD  1 
ATOM 1199 N N   . ALA A 1 251 ? 107.963 139.842 85.697  1.00 109.43 ? 195 ALA R N   1 
ATOM 1200 C CA  . ALA A 1 251 ? 108.650 139.058 86.710  1.00 111.42 ? 195 ALA R CA  1 
ATOM 1201 C C   . ALA A 1 251 ? 109.314 139.995 87.707  1.00 112.70 ? 195 ALA R C   1 
ATOM 1202 O O   . ALA A 1 251 ? 109.614 141.152 87.399  1.00 109.99 ? 195 ALA R O   1 
ATOM 1203 C CB  . ALA A 1 251 ? 109.687 138.116 86.087  1.00 111.66 ? 195 ALA R CB  1 
ATOM 1204 N N   . CYS A 1 252 ? 109.544 139.474 88.912  1.00 115.11 ? 196 CYS R N   1 
ATOM 1205 C CA  . CYS A 1 252 ? 110.198 140.239 89.965  1.00 113.25 ? 196 CYS R CA  1 
ATOM 1206 C C   . CYS A 1 252 ? 111.682 140.349 89.638  1.00 112.88 ? 196 CYS R C   1 
ATOM 1207 O O   . CYS A 1 252 ? 112.493 139.532 90.087  1.00 114.21 ? 196 CYS R O   1 
ATOM 1208 C CB  . CYS A 1 252 ? 109.953 139.582 91.329  1.00 110.92 ? 196 CYS R CB  1 
ATOM 1209 S SG  . CYS A 1 252 ? 110.986 140.148 92.705  1.00 114.88 ? 196 CYS R SG  1 
ATOM 1210 N N   . TYR A 1 253 ? 112.034 141.348 88.838  1.00 117.41 ? 197 TYR R N   1 
ATOM 1211 C CA  . TYR A 1 253 ? 113.361 141.520 88.272  1.00 118.82 ? 197 TYR R CA  1 
ATOM 1212 C C   . TYR A 1 253 ? 114.048 142.709 88.944  1.00 120.86 ? 197 TYR R C   1 
ATOM 1213 O O   . TYR A 1 253 ? 113.531 143.292 89.903  1.00 120.41 ? 197 TYR R O   1 
ATOM 1214 C CB  . TYR A 1 253 ? 113.239 141.691 86.756  1.00 119.51 ? 197 TYR R CB  1 
ATOM 1215 C CG  . TYR A 1 253 ? 114.469 141.325 85.960  1.00 117.32 ? 197 TYR R CG  1 
ATOM 1216 C CD1 . TYR A 1 253 ? 114.988 142.196 85.013  1.00 116.36 ? 197 TYR R CD1 1 
ATOM 1217 C CD2 . TYR A 1 253 ? 115.094 140.100 86.137  1.00 117.36 ? 197 TYR R CD2 1 
ATOM 1218 C CE1 . TYR A 1 253 ? 116.105 141.863 84.275  1.00 118.25 ? 197 TYR R CE1 1 
ATOM 1219 C CE2 . TYR A 1 253 ? 116.211 139.758 85.403  1.00 118.93 ? 197 TYR R CE2 1 
ATOM 1220 C CZ  . TYR A 1 253 ? 116.712 140.643 84.473  1.00 120.01 ? 197 TYR R CZ  1 
ATOM 1221 O OH  . TYR A 1 253 ? 117.826 140.304 83.739  1.00 121.12 ? 197 TYR R OH  1 
ATOM 1222 N N   . GLU A 1 254 ? 115.226 143.069 88.444  1.00 125.23 ? 198 GLU R N   1 
ATOM 1223 C CA  . GLU A 1 254 ? 115.991 144.178 88.996  1.00 122.86 ? 198 GLU R CA  1 
ATOM 1224 C C   . GLU A 1 254 ? 115.923 145.390 88.075  1.00 122.64 ? 198 GLU R C   1 
ATOM 1225 O O   . GLU A 1 254 ? 115.830 145.262 86.852  1.00 123.08 ? 198 GLU R O   1 
ATOM 1226 C CB  . GLU A 1 254 ? 117.449 143.779 89.226  1.00 122.67 ? 198 GLU R CB  1 
ATOM 1227 C CG  . GLU A 1 254 ? 117.675 142.288 89.396  1.00 124.23 ? 198 GLU R CG  1 
ATOM 1228 C CD  . GLU A 1 254 ? 119.144 141.918 89.386  1.00 123.14 ? 198 GLU R CD  1 
ATOM 1229 O OE1 . GLU A 1 254 ? 119.985 142.823 89.564  1.00 122.82 ? 198 GLU R OE1 1 
ATOM 1230 O OE2 . GLU A 1 254 ? 119.458 140.724 89.204  1.00 121.47 ? 198 GLU R OE2 1 
ATOM 1231 N N   . ASP A 1 255 ? 115.969 146.576 88.681  1.00 129.52 ? 199 ASP R N   1 
ATOM 1232 C CA  . ASP A 1 255 ? 115.868 147.837 87.949  1.00 131.03 ? 199 ASP R CA  1 
ATOM 1233 C C   . ASP A 1 255 ? 116.753 148.866 88.638  1.00 129.86 ? 199 ASP R C   1 
ATOM 1234 O O   . ASP A 1 255 ? 116.428 149.332 89.734  1.00 128.73 ? 199 ASP R O   1 
ATOM 1235 C CB  . ASP A 1 255 ? 114.417 148.320 87.882  1.00 132.00 ? 199 ASP R CB  1 
ATOM 1236 C CG  . ASP A 1 255 ? 114.257 149.598 87.073  1.00 131.46 ? 199 ASP R CG  1 
ATOM 1237 O OD1 . ASP A 1 255 ? 114.763 150.656 87.503  1.00 129.86 ? 199 ASP R OD1 1 
ATOM 1238 O OD2 . ASP A 1 255 ? 113.618 149.543 86.002  1.00 130.30 ? 199 ASP R OD2 1 
ATOM 1239 N N   . MET A 1 256 ? 117.869 149.219 87.998  1.00 127.61 ? 200 MET R N   1 
ATOM 1240 C CA  . MET A 1 256 ? 118.737 150.274 88.497  1.00 127.90 ? 200 MET R CA  1 
ATOM 1241 C C   . MET A 1 256 ? 119.202 151.240 87.416  1.00 128.39 ? 200 MET R C   1 
ATOM 1242 O O   . MET A 1 256 ? 119.985 152.147 87.721  1.00 129.11 ? 200 MET R O   1 
ATOM 1243 C CB  . MET A 1 256 ? 119.965 149.679 89.203  1.00 128.06 ? 200 MET R CB  1 
ATOM 1244 C CG  . MET A 1 256 ? 120.717 148.639 88.393  1.00 128.29 ? 200 MET R CG  1 
ATOM 1245 S SD  . MET A 1 256 ? 121.389 147.331 89.435  1.00 129.61 ? 200 MET R SD  1 
ATOM 1246 C CE  . MET A 1 256 ? 120.007 146.201 89.489  1.00 127.78 ? 200 MET R CE  1 
ATOM 1247 N N   . GLY A 1 257 ? 118.753 151.083 86.181  1.00 125.49 ? 201 GLY R N   1 
ATOM 1248 C CA  . GLY A 1 257 ? 119.151 151.986 85.122  1.00 124.27 ? 201 GLY R CA  1 
ATOM 1249 C C   . GLY A 1 257 ? 118.958 151.356 83.760  1.00 124.49 ? 201 GLY R C   1 
ATOM 1250 O O   . GLY A 1 257 ? 118.481 150.229 83.626  1.00 127.04 ? 201 GLY R O   1 
ATOM 1251 N N   . ASN A 1 258 ? 119.340 152.127 82.739  1.00 118.44 ? 202 ASN R N   1 
ATOM 1252 C CA  . ASN A 1 258 ? 119.216 151.655 81.363  1.00 118.30 ? 202 ASN R CA  1 
ATOM 1253 C C   . ASN A 1 258 ? 120.227 150.560 81.047  1.00 119.36 ? 202 ASN R C   1 
ATOM 1254 O O   . ASN A 1 258 ? 119.981 149.727 80.167  1.00 119.80 ? 202 ASN R O   1 
ATOM 1255 C CB  . ASN A 1 258 ? 119.379 152.823 80.392  1.00 119.05 ? 202 ASN R CB  1 
ATOM 1256 C CG  . ASN A 1 258 ? 118.082 153.188 79.699  1.00 120.22 ? 202 ASN R CG  1 
ATOM 1257 O OD1 . ASN A 1 258 ? 117.052 152.544 79.902  1.00 118.79 ? 202 ASN R OD1 1 
ATOM 1258 N ND2 . ASN A 1 258 ? 118.125 154.228 78.873  1.00 120.20 ? 202 ASN R ND2 1 
ATOM 1259 N N   . ASN A 1 259 ? 121.359 150.542 81.746  1.00 128.84 ? 203 ASN R N   1 
ATOM 1260 C CA  . ASN A 1 259 ? 122.417 149.555 81.539  1.00 128.64 ? 203 ASN R CA  1 
ATOM 1261 C C   . ASN A 1 259 ? 122.388 148.479 82.615  1.00 129.16 ? 203 ASN R C   1 
ATOM 1262 O O   . ASN A 1 259 ? 123.431 148.034 83.100  1.00 128.33 ? 203 ASN R O   1 
ATOM 1263 C CB  . ASN A 1 259 ? 123.779 150.239 81.493  1.00 128.47 ? 203 ASN R CB  1 
ATOM 1264 C CG  . ASN A 1 259 ? 123.967 151.077 80.244  1.00 129.74 ? 203 ASN R CG  1 
ATOM 1265 O OD1 . ASN A 1 259 ? 124.219 152.280 80.321  1.00 129.85 ? 203 ASN R OD1 1 
ATOM 1266 N ND2 . ASN A 1 259 ? 123.839 150.445 79.084  1.00 128.55 ? 203 ASN R ND2 1 
ATOM 1267 N N   . THR A 1 260 ? 121.183 148.056 83.004  1.00 129.26 ? 204 THR R N   1 
ATOM 1268 C CA  . THR A 1 260 ? 121.011 147.180 84.156  1.00 129.29 ? 204 THR R CA  1 
ATOM 1269 C C   . THR A 1 260 ? 121.645 145.806 83.956  1.00 129.50 ? 204 THR R C   1 
ATOM 1270 O O   . THR A 1 260 ? 121.947 145.134 84.943  1.00 128.72 ? 204 THR R O   1 
ATOM 1271 C CB  . THR A 1 260 ? 119.515 147.044 84.470  1.00 128.92 ? 204 THR R CB  1 
ATOM 1272 O OG1 . THR A 1 260 ? 118.958 148.344 84.697  1.00 129.20 ? 204 THR R OG1 1 
ATOM 1273 C CG2 . THR A 1 260 ? 119.279 146.203 85.720  1.00 127.95 ? 204 THR R CG2 1 
ATOM 1274 N N   . ALA A 1 261 ? 121.868 145.371 82.713  1.00 126.04 ? 205 ALA R N   1 
ATOM 1275 C CA  . ALA A 1 261 ? 122.425 144.038 82.488  1.00 124.13 ? 205 ALA R CA  1 
ATOM 1276 C C   . ALA A 1 261 ? 123.815 143.899 83.104  1.00 124.28 ? 205 ALA R C   1 
ATOM 1277 O O   . ALA A 1 261 ? 124.093 142.944 83.845  1.00 125.78 ? 205 ALA R O   1 
ATOM 1278 C CB  . ALA A 1 261 ? 122.467 143.737 80.990  1.00 123.62 ? 205 ALA R CB  1 
ATOM 1279 N N   . ASN A 1 262 ? 124.707 144.847 82.810  1.00 122.38 ? 206 ASN R N   1 
ATOM 1280 C CA  . ASN A 1 262 ? 126.051 144.782 83.371  1.00 122.66 ? 206 ASN R CA  1 
ATOM 1281 C C   . ASN A 1 262 ? 126.031 144.949 84.883  1.00 122.68 ? 206 ASN R C   1 
ATOM 1282 O O   . ASN A 1 262 ? 126.858 144.356 85.584  1.00 122.56 ? 206 ASN R O   1 
ATOM 1283 C CB  . ASN A 1 262 ? 126.941 145.843 82.725  1.00 123.80 ? 206 ASN R CB  1 
ATOM 1284 C CG  . ASN A 1 262 ? 126.608 146.071 81.263  1.00 124.07 ? 206 ASN R CG  1 
ATOM 1285 O OD1 . ASN A 1 262 ? 126.731 145.165 80.439  1.00 123.87 ? 206 ASN R OD1 1 
ATOM 1286 N ND2 . ASN A 1 262 ? 126.182 147.284 80.935  1.00 122.45 ? 206 ASN R ND2 1 
ATOM 1287 N N   . TRP A 1 263 ? 125.091 145.739 85.404  1.00 121.62 ? 207 TRP R N   1 
ATOM 1288 C CA  . TRP A 1 263 ? 124.969 145.879 86.849  1.00 123.94 ? 207 TRP R CA  1 
ATOM 1289 C C   . TRP A 1 263 ? 124.489 144.584 87.496  1.00 123.46 ? 207 TRP R C   1 
ATOM 1290 O O   . TRP A 1 263 ? 124.901 144.263 88.613  1.00 121.06 ? 207 TRP R O   1 
ATOM 1291 C CB  . TRP A 1 263 ? 124.031 147.038 87.171  1.00 122.22 ? 207 TRP R CB  1 
ATOM 1292 C CG  . TRP A 1 263 ? 124.651 148.370 86.889  1.00 122.23 ? 207 TRP R CG  1 
ATOM 1293 C CD1 . TRP A 1 263 ? 124.268 149.264 85.933  1.00 122.51 ? 207 TRP R CD1 1 
ATOM 1294 C CD2 . TRP A 1 263 ? 125.773 148.956 87.560  1.00 121.66 ? 207 TRP R CD2 1 
ATOM 1295 N NE1 . TRP A 1 263 ? 125.078 150.372 85.969  1.00 123.50 ? 207 TRP R NE1 1 
ATOM 1296 C CE2 . TRP A 1 263 ? 126.010 150.208 86.960  1.00 122.12 ? 207 TRP R CE2 1 
ATOM 1297 C CE3 . TRP A 1 263 ? 126.598 148.545 88.611  1.00 121.39 ? 207 TRP R CE3 1 
ATOM 1298 C CZ2 . TRP A 1 263 ? 127.037 151.052 87.375  1.00 121.81 ? 207 TRP R CZ2 1 
ATOM 1299 C CZ3 . TRP A 1 263 ? 127.616 149.385 89.022  1.00 123.01 ? 207 TRP R CZ3 1 
ATOM 1300 C CH2 . TRP A 1 263 ? 127.827 150.624 88.405  1.00 122.45 ? 207 TRP R CH2 1 
ATOM 1301 N N   . ARG A 1 264 ? 123.630 143.829 86.807  1.00 117.92 ? 208 ARG R N   1 
ATOM 1302 C CA  . ARG A 1 264 ? 123.257 142.496 87.269  1.00 115.55 ? 208 ARG R CA  1 
ATOM 1303 C C   . ARG A 1 264 ? 124.460 141.567 87.275  1.00 112.95 ? 208 ARG R C   1 
ATOM 1304 O O   . ARG A 1 264 ? 124.647 140.780 88.211  1.00 112.75 ? 208 ARG R O   1 
ATOM 1305 C CB  . ARG A 1 264 ? 122.154 141.923 86.379  1.00 115.50 ? 208 ARG R CB  1 
ATOM 1306 C CG  . ARG A 1 264 ? 120.825 142.647 86.467  1.00 115.50 ? 208 ARG R CG  1 
ATOM 1307 C CD  . ARG A 1 264 ? 119.728 141.903 85.717  1.00 114.12 ? 208 ARG R CD  1 
ATOM 1308 N NE  . ARG A 1 264 ? 119.164 140.796 86.479  1.00 114.54 ? 208 ARG R NE  1 
ATOM 1309 C CZ  . ARG A 1 264 ? 119.575 139.539 86.392  1.00 114.58 ? 208 ARG R CZ  1 
ATOM 1310 N NH1 . ARG A 1 264 ? 120.543 139.184 85.563  1.00 114.98 ? 208 ARG R NH1 1 
ATOM 1311 N NH2 . ARG A 1 264 ? 118.995 138.612 87.149  1.00 116.02 ? 208 ARG R NH2 1 
ATOM 1312 N N   . MET A 1 265 ? 125.282 141.638 86.227  1.00 110.10 ? 209 MET R N   1 
ATOM 1313 C CA  . MET A 1 265 ? 126.493 140.823 86.192  1.00 112.38 ? 209 MET R CA  1 
ATOM 1314 C C   . MET A 1 265 ? 127.417 141.173 87.352  1.00 113.87 ? 209 MET R C   1 
ATOM 1315 O O   . MET A 1 265 ? 128.040 140.289 87.952  1.00 113.54 ? 209 MET R O   1 
ATOM 1316 C CB  . MET A 1 265 ? 127.211 141.003 84.855  1.00 112.81 ? 209 MET R CB  1 
ATOM 1317 N N   . LEU A 1 266 ? 127.524 142.464 87.674  1.00 112.33 ? 210 LEU R N   1 
ATOM 1318 C CA  . LEU A 1 266 ? 128.324 142.885 88.821  1.00 112.53 ? 210 LEU R CA  1 
ATOM 1319 C C   . LEU A 1 266 ? 127.729 142.385 90.133  1.00 111.48 ? 210 LEU R C   1 
ATOM 1320 O O   . LEU A 1 266 ? 128.456 141.905 91.010  1.00 109.74 ? 210 LEU R O   1 
ATOM 1321 C CB  . LEU A 1 266 ? 128.449 144.409 88.839  1.00 110.40 ? 210 LEU R CB  1 
ATOM 1322 C CG  . LEU A 1 266 ? 129.721 144.987 88.220  1.00 109.21 ? 210 LEU R CG  1 
ATOM 1323 C CD1 . LEU A 1 266 ? 129.701 146.509 88.258  1.00 107.65 ? 210 LEU R CD1 1 
ATOM 1324 C CD2 . LEU A 1 266 ? 130.954 144.440 88.922  1.00 111.17 ? 210 LEU R CD2 1 
ATOM 1325 N N   . LEU A 1 267 ? 126.406 142.493 90.286  1.00 107.59 ? 211 LEU R N   1 
ATOM 1326 C CA  . LEU A 1 267 ? 125.753 142.079 91.524  1.00 106.56 ? 211 LEU R CA  1 
ATOM 1327 C C   . LEU A 1 267 ? 125.813 140.572 91.720  1.00 107.00 ? 211 LEU R C   1 
ATOM 1328 O O   . LEU A 1 267 ? 125.740 140.092 92.856  1.00 108.50 ? 211 LEU R O   1 
ATOM 1329 C CB  . LEU A 1 267 ? 124.298 142.550 91.534  1.00 105.22 ? 211 LEU R CB  1 
ATOM 1330 C CG  . LEU A 1 267 ? 123.942 143.764 92.393  1.00 107.74 ? 211 LEU R CG  1 
ATOM 1331 C CD1 . LEU A 1 267 ? 122.440 143.843 92.592  1.00 106.11 ? 211 LEU R CD1 1 
ATOM 1332 C CD2 . LEU A 1 267 ? 124.649 143.699 93.734  1.00 106.48 ? 211 LEU R CD2 1 
ATOM 1333 N N   . ARG A 1 268 ? 125.929 139.812 90.631  1.00 95.32  ? 212 ARG R N   1 
ATOM 1334 C CA  . ARG A 1 268 ? 126.026 138.363 90.748  1.00 94.51  ? 212 ARG R CA  1 
ATOM 1335 C C   . ARG A 1 268 ? 127.304 137.932 91.460  1.00 96.39  ? 212 ARG R C   1 
ATOM 1336 O O   . ARG A 1 268 ? 127.359 136.822 91.997  1.00 98.02  ? 212 ARG R O   1 
ATOM 1337 C CB  . ARG A 1 268 ? 125.933 137.734 89.353  1.00 95.42  ? 212 ARG R CB  1 
ATOM 1338 C CG  . ARG A 1 268 ? 126.302 136.264 89.269  1.00 93.70  ? 212 ARG R CG  1 
ATOM 1339 C CD  . ARG A 1 268 ? 125.693 135.627 88.039  1.00 93.22  ? 212 ARG R CD  1 
ATOM 1340 N NE  . ARG A 1 268 ? 124.346 136.122 87.788  1.00 93.79  ? 212 ARG R NE  1 
ATOM 1341 C CZ  . ARG A 1 268 ? 123.851 136.367 86.583  1.00 95.08  ? 212 ARG R CZ  1 
ATOM 1342 N NH1 . ARG A 1 268 ? 124.568 136.171 85.488  1.00 94.36  ? 212 ARG R NH1 1 
ATOM 1343 N NH2 . ARG A 1 268 ? 122.606 136.819 86.473  1.00 98.95  ? 212 ARG R NH2 1 
ATOM 1344 N N   . ILE A 1 269 ? 128.320 138.796 91.508  1.00 97.21  ? 213 ILE R N   1 
ATOM 1345 C CA  . ILE A 1 269 ? 129.593 138.412 92.108  1.00 97.70  ? 213 ILE R CA  1 
ATOM 1346 C C   . ILE A 1 269 ? 129.475 138.142 93.605  1.00 95.91  ? 213 ILE R C   1 
ATOM 1347 O O   . ILE A 1 269 ? 130.311 137.422 94.162  1.00 96.45  ? 213 ILE R O   1 
ATOM 1348 C CB  . ILE A 1 269 ? 130.661 139.486 91.820  1.00 96.09  ? 213 ILE R CB  1 
ATOM 1349 C CG1 . ILE A 1 269 ? 132.014 138.829 91.540  1.00 95.87  ? 213 ILE R CG1 1 
ATOM 1350 C CG2 . ILE A 1 269 ? 130.777 140.471 92.974  1.00 95.49  ? 213 ILE R CG2 1 
ATOM 1351 C CD1 . ILE A 1 269 ? 132.996 139.739 90.840  1.00 96.54  ? 213 ILE R CD1 1 
ATOM 1352 N N   . LEU A 1 270 ? 128.464 138.694 94.280  1.00 88.11  ? 214 LEU R N   1 
ATOM 1353 C CA  . LEU A 1 270 ? 128.319 138.453 95.714  1.00 88.94  ? 214 LEU R CA  1 
ATOM 1354 C C   . LEU A 1 270 ? 127.764 137.060 96.016  1.00 91.51  ? 214 LEU R C   1 
ATOM 1355 O O   . LEU A 1 270 ? 128.404 136.312 96.767  1.00 92.68  ? 214 LEU R O   1 
ATOM 1356 C CB  . LEU A 1 270 ? 127.457 139.534 96.378  1.00 87.47  ? 214 LEU R CB  1 
ATOM 1357 C CG  . LEU A 1 270 ? 127.911 140.995 96.291  1.00 90.09  ? 214 LEU R CG  1 
ATOM 1358 C CD1 . LEU A 1 270 ? 129.428 141.094 96.377  1.00 94.07  ? 214 LEU R CD1 1 
ATOM 1359 C CD2 . LEU A 1 270 ? 127.393 141.684 95.041  1.00 88.79  ? 214 LEU R CD2 1 
ATOM 1360 N N   . PRO A 1 271 ? 126.601 136.660 95.483  1.00 84.83  ? 215 PRO R N   1 
ATOM 1361 C CA  . PRO A 1 271 ? 126.062 135.339 95.851  1.00 82.39  ? 215 PRO R CA  1 
ATOM 1362 C C   . PRO A 1 271 ? 126.940 134.174 95.433  1.00 83.52  ? 215 PRO R C   1 
ATOM 1363 O O   . PRO A 1 271 ? 126.795 133.083 95.997  1.00 84.30  ? 215 PRO R O   1 
ATOM 1364 C CB  . PRO A 1 271 ? 124.702 135.296 95.140  1.00 80.74  ? 215 PRO R CB  1 
ATOM 1365 C CG  . PRO A 1 271 ? 124.802 136.282 94.054  1.00 83.78  ? 215 PRO R CG  1 
ATOM 1366 C CD  . PRO A 1 271 ? 125.695 137.366 94.558  1.00 83.82  ? 215 PRO R CD  1 
ATOM 1367 N N   . GLN A 1 272 ? 127.837 134.357 94.466  1.00 84.89  ? 216 GLN R N   1 
ATOM 1368 C CA  . GLN A 1 272 ? 128.735 133.285 94.059  1.00 85.16  ? 216 GLN R CA  1 
ATOM 1369 C C   . GLN A 1 272 ? 130.079 133.323 94.773  1.00 88.92  ? 216 GLN R C   1 
ATOM 1370 O O   . GLN A 1 272 ? 130.883 132.404 94.586  1.00 89.93  ? 216 GLN R O   1 
ATOM 1371 C CB  . GLN A 1 272 ? 128.962 133.326 92.542  1.00 81.83  ? 216 GLN R CB  1 
ATOM 1372 C CG  . GLN A 1 272 ? 127.759 133.781 91.716  1.00 86.14  ? 216 GLN R CG  1 
ATOM 1373 C CD  . GLN A 1 272 ? 126.568 132.831 91.758  1.00 88.87  ? 216 GLN R CD  1 
ATOM 1374 O OE1 . GLN A 1 272 ? 126.469 131.955 92.615  1.00 90.97  ? 216 GLN R OE1 1 
ATOM 1375 N NE2 . GLN A 1 272 ? 125.645 133.019 90.824  1.00 88.39  ? 216 GLN R NE2 1 
ATOM 1376 N N   . SER A 1 273 ? 130.344 134.348 95.582  1.00 84.42  ? 217 SER R N   1 
ATOM 1377 C CA  . SER A 1 273 ? 131.587 134.455 96.337  1.00 82.50  ? 217 SER R CA  1 
ATOM 1378 C C   . SER A 1 273 ? 131.378 134.280 97.832  1.00 81.80  ? 217 SER R C   1 
ATOM 1379 O O   . SER A 1 273 ? 132.090 133.500 98.470  1.00 84.44  ? 217 SER R O   1 
ATOM 1380 C CB  . SER A 1 273 ? 132.258 135.808 96.064  1.00 84.16  ? 217 SER R CB  1 
ATOM 1381 O OG  . SER A 1 273 ? 131.992 136.724 97.110  1.00 85.75  ? 217 SER R OG  1 
ATOM 1382 N N   . PHE A 1 274 ? 130.417 134.992 98.412  1.00 81.56  ? 218 PHE R N   1 
ATOM 1383 C CA  . PHE A 1 274 ? 130.030 134.784 99.799  1.00 84.59  ? 218 PHE R CA  1 
ATOM 1384 C C   . PHE A 1 274 ? 128.964 133.711 99.949  1.00 85.70  ? 218 PHE R C   1 
ATOM 1385 O O   . PHE A 1 274 ? 128.500 133.467 101.068 1.00 87.76  ? 218 PHE R O   1 
ATOM 1386 C CB  . PHE A 1 274 ? 129.531 136.094 100.418 1.00 85.55  ? 218 PHE R CB  1 
ATOM 1387 C CG  . PHE A 1 274 ? 130.619 137.091 100.687 1.00 86.29  ? 218 PHE R CG  1 
ATOM 1388 C CD1 . PHE A 1 274 ? 131.786 136.704 101.327 1.00 86.76  ? 218 PHE R CD1 1 
ATOM 1389 C CD2 . PHE A 1 274 ? 130.475 138.414 100.307 1.00 82.57  ? 218 PHE R CD2 1 
ATOM 1390 C CE1 . PHE A 1 274 ? 132.790 137.617 101.579 1.00 87.40  ? 218 PHE R CE1 1 
ATOM 1391 C CE2 . PHE A 1 274 ? 131.477 139.333 100.556 1.00 86.95  ? 218 PHE R CE2 1 
ATOM 1392 C CZ  . PHE A 1 274 ? 132.636 138.933 101.194 1.00 89.01  ? 218 PHE R CZ  1 
ATOM 1393 N N   . GLY A 1 275 ? 128.566 133.070 98.855  1.00 73.98  ? 219 GLY R N   1 
ATOM 1394 C CA  . GLY A 1 275 ? 127.554 132.039 98.913  1.00 72.87  ? 219 GLY R CA  1 
ATOM 1395 C C   . GLY A 1 275 ? 128.055 130.682 98.470  1.00 73.26  ? 219 GLY R C   1 
ATOM 1396 O O   . GLY A 1 275 ? 127.477 129.658 98.842  1.00 80.78  ? 219 GLY R O   1 
ATOM 1397 N N   . PHE A 1 276 ? 129.103 130.647 97.660  1.00 60.06  ? 220 PHE R N   1 
ATOM 1398 C CA  . PHE A 1 276 ? 129.614 129.334 97.284  1.00 66.79  ? 220 PHE R CA  1 
ATOM 1399 C C   . PHE A 1 276 ? 131.113 129.172 97.482  1.00 73.19  ? 220 PHE R C   1 
ATOM 1400 O O   . PHE A 1 276 ? 131.548 128.107 97.917  1.00 78.33  ? 220 PHE R O   1 
ATOM 1401 C CB  . PHE A 1 276 ? 129.261 129.030 95.825  1.00 64.85  ? 220 PHE R CB  1 
ATOM 1402 C CG  . PHE A 1 276 ? 129.538 127.612 95.422  1.00 59.17  ? 220 PHE R CG  1 
ATOM 1403 C CD1 . PHE A 1 276 ? 128.742 126.580 95.886  1.00 59.61  ? 220 PHE R CD1 1 
ATOM 1404 C CD2 . PHE A 1 276 ? 130.595 127.311 94.582  1.00 63.39  ? 220 PHE R CD2 1 
ATOM 1405 C CE1 . PHE A 1 276 ? 128.994 125.276 95.519  1.00 62.63  ? 220 PHE R CE1 1 
ATOM 1406 C CE2 . PHE A 1 276 ? 130.851 126.008 94.212  1.00 67.13  ? 220 PHE R CE2 1 
ATOM 1407 C CZ  . PHE A 1 276 ? 130.049 124.989 94.681  1.00 64.92  ? 220 PHE R CZ  1 
ATOM 1408 N N   . ILE A 1 277 ? 131.913 130.197 97.190  1.00 68.28  ? 221 ILE R N   1 
ATOM 1409 C CA  . ILE A 1 277 ? 133.364 130.021 97.182  1.00 61.30  ? 221 ILE R CA  1 
ATOM 1410 C C   . ILE A 1 277 ? 133.901 129.925 98.604  1.00 63.66  ? 221 ILE R C   1 
ATOM 1411 O O   . ILE A 1 277 ? 134.556 128.944 98.976  1.00 66.39  ? 221 ILE R O   1 
ATOM 1412 C CB  . ILE A 1 277 ? 134.046 131.158 96.401  1.00 60.35  ? 221 ILE R CB  1 
ATOM 1413 C CG1 . ILE A 1 277 ? 133.722 131.052 94.912  1.00 65.29  ? 221 ILE R CG1 1 
ATOM 1414 C CG2 . ILE A 1 277 ? 135.548 131.122 96.615  1.00 64.50  ? 221 ILE R CG2 1 
ATOM 1415 C CD1 . ILE A 1 277 ? 134.074 132.294 94.125  1.00 66.42  ? 221 ILE R CD1 1 
ATOM 1416 N N   . VAL A 1 278 ? 133.641 130.951 99.415  1.00 57.08  ? 222 VAL R N   1 
ATOM 1417 C CA  . VAL A 1 278 ? 134.126 130.948 100.796 1.00 53.66  ? 222 VAL R CA  1 
ATOM 1418 C C   . VAL A 1 278 ? 133.567 129.774 101.596 1.00 59.16  ? 222 VAL R C   1 
ATOM 1419 O O   . VAL A 1 278 ? 134.352 129.095 102.280 1.00 62.52  ? 222 VAL R O   1 
ATOM 1420 C CB  . VAL A 1 278 ? 133.844 132.307 101.456 1.00 56.27  ? 222 VAL R CB  1 
ATOM 1421 C CG1 . VAL A 1 278 ? 133.894 132.190 102.971 1.00 58.09  ? 222 VAL R CG1 1 
ATOM 1422 C CG2 . VAL A 1 278 ? 134.830 133.350 100.961 1.00 64.27  ? 222 VAL R CG2 1 
ATOM 1423 N N   . PRO A 1 279 ? 132.257 129.493 101.584 1.00 57.77  ? 223 PRO R N   1 
ATOM 1424 C CA  . PRO A 1 279 ? 131.775 128.320 102.334 1.00 59.56  ? 223 PRO R CA  1 
ATOM 1425 C C   . PRO A 1 279 ? 132.342 127.003 101.840 1.00 61.37  ? 223 PRO R C   1 
ATOM 1426 O O   . PRO A 1 279 ? 132.627 126.120 102.657 1.00 64.95  ? 223 PRO R O   1 
ATOM 1427 C CB  . PRO A 1 279 ? 130.254 128.393 102.150 1.00 52.89  ? 223 PRO R CB  1 
ATOM 1428 C CG  . PRO A 1 279 ? 129.987 129.823 101.852 1.00 61.57  ? 223 PRO R CG  1 
ATOM 1429 C CD  . PRO A 1 279 ? 131.133 130.255 101.013 1.00 60.11  ? 223 PRO R CD  1 
ATOM 1430 N N   . LEU A 1 280 ? 132.521 126.838 100.526 1.00 50.49  ? 224 LEU R N   1 
ATOM 1431 C CA  . LEU A 1 280 ? 133.114 125.601 100.028 1.00 52.38  ? 224 LEU R CA  1 
ATOM 1432 C C   . LEU A 1 280 ? 134.554 125.458 100.495 1.00 60.52  ? 224 LEU R C   1 
ATOM 1433 O O   . LEU A 1 280 ? 134.978 124.368 100.891 1.00 60.19  ? 224 LEU R O   1 
ATOM 1434 C CB  . LEU A 1 280 ? 133.047 125.542 98.504  1.00 46.33  ? 224 LEU R CB  1 
ATOM 1435 C CG  . LEU A 1 280 ? 133.532 124.226 97.899  1.00 48.71  ? 224 LEU R CG  1 
ATOM 1436 C CD1 . LEU A 1 280 ? 132.554 123.108 98.215  1.00 50.05  ? 224 LEU R CD1 1 
ATOM 1437 C CD2 . LEU A 1 280 ? 133.738 124.358 96.401  1.00 55.43  ? 224 LEU R CD2 1 
ATOM 1438 N N   . LEU A 1 281 ? 135.321 126.550 100.460 1.00 55.84  ? 225 LEU R N   1 
ATOM 1439 C CA  . LEU A 1 281 ? 136.697 126.494 100.942 1.00 53.87  ? 225 LEU R CA  1 
ATOM 1440 C C   . LEU A 1 281 ? 136.742 126.146 102.424 1.00 58.50  ? 225 LEU R C   1 
ATOM 1441 O O   . LEU A 1 281 ? 137.541 125.300 102.850 1.00 56.31  ? 225 LEU R O   1 
ATOM 1442 C CB  . LEU A 1 281 ? 137.398 127.827 100.682 1.00 47.84  ? 225 LEU R CB  1 
ATOM 1443 C CG  . LEU A 1 281 ? 137.741 128.156 99.228  1.00 48.54  ? 225 LEU R CG  1 
ATOM 1444 C CD1 . LEU A 1 281 ? 138.626 129.388 99.157  1.00 54.99  ? 225 LEU R CD1 1 
ATOM 1445 C CD2 . LEU A 1 281 ? 138.408 126.974 98.547  1.00 52.92  ? 225 LEU R CD2 1 
ATOM 1446 N N   . ILE A 1 282 ? 135.879 126.779 103.223 1.00 47.50  ? 226 ILE R N   1 
ATOM 1447 C CA  . ILE A 1 282 ? 135.864 126.524 104.661 1.00 47.36  ? 226 ILE R CA  1 
ATOM 1448 C C   . ILE A 1 282 ? 135.500 125.072 104.940 1.00 56.99  ? 226 ILE R C   1 
ATOM 1449 O O   . ILE A 1 282 ? 136.155 124.391 105.740 1.00 59.92  ? 226 ILE R O   1 
ATOM 1450 C CB  . ILE A 1 282 ? 134.897 127.490 105.368 1.00 39.81  ? 226 ILE R CB  1 
ATOM 1451 C CG1 . ILE A 1 282 ? 135.428 128.922 105.313 1.00 48.81  ? 226 ILE R CG1 1 
ATOM 1452 C CG2 . ILE A 1 282 ? 134.683 127.066 106.804 1.00 50.54  ? 226 ILE R CG2 1 
ATOM 1453 C CD1 . ILE A 1 282 ? 134.475 129.941 105.894 1.00 51.59  ? 226 ILE R CD1 1 
ATOM 1454 N N   . MET A 1 283 ? 134.447 124.576 104.285 1.00 51.12  ? 227 MET R N   1 
ATOM 1455 C CA  . MET A 1 283 ? 134.023 123.198 104.502 1.00 44.03  ? 227 MET R CA  1 
ATOM 1456 C C   . MET A 1 283 ? 135.102 122.216 104.074 1.00 46.29  ? 227 MET R C   1 
ATOM 1457 O O   . MET A 1 283 ? 135.380 121.244 104.784 1.00 51.76  ? 227 MET R O   1 
ATOM 1458 C CB  . MET A 1 283 ? 132.722 122.922 103.750 1.00 44.04  ? 227 MET R CB  1 
ATOM 1459 C CG  . MET A 1 283 ? 131.483 123.483 104.423 1.00 47.88  ? 227 MET R CG  1 
ATOM 1460 S SD  . MET A 1 283 ? 129.945 122.825 103.750 1.00 63.73  ? 227 MET R SD  1 
ATOM 1461 C CE  . MET A 1 283 ? 130.555 121.488 102.726 1.00 50.85  ? 227 MET R CE  1 
ATOM 1462 N N   . LEU A 1 284 ? 135.731 122.456 102.920 1.00 41.60  ? 228 LEU R N   1 
ATOM 1463 C CA  . LEU A 1 284 ? 136.777 121.559 102.445 1.00 45.42  ? 228 LEU R CA  1 
ATOM 1464 C C   . LEU A 1 284 ? 137.935 121.505 103.429 1.00 52.57  ? 228 LEU R C   1 
ATOM 1465 O O   . LEU A 1 284 ? 138.369 120.420 103.830 1.00 53.14  ? 228 LEU R O   1 
ATOM 1466 C CB  . LEU A 1 284 ? 137.259 122.005 101.064 1.00 48.61  ? 228 LEU R CB  1 
ATOM 1467 N N   . PHE A 1 285 ? 138.434 122.671 103.848 1.00 54.62  ? 229 PHE R N   1 
ATOM 1468 C CA  . PHE A 1 285 ? 139.537 122.717 104.805 1.00 52.59  ? 229 PHE R CA  1 
ATOM 1469 C C   . PHE A 1 285 ? 139.176 121.997 106.102 1.00 56.74  ? 229 PHE R C   1 
ATOM 1470 O O   . PHE A 1 285 ? 139.902 121.096 106.556 1.00 49.91  ? 229 PHE R O   1 
ATOM 1471 C CB  . PHE A 1 285 ? 139.903 124.180 105.066 1.00 49.17  ? 229 PHE R CB  1 
ATOM 1472 C CG  . PHE A 1 285 ? 140.655 124.415 106.346 1.00 52.51  ? 229 PHE R CG  1 
ATOM 1473 C CD1 . PHE A 1 285 ? 141.853 123.773 106.600 1.00 53.42  ? 229 PHE R CD1 1 
ATOM 1474 C CD2 . PHE A 1 285 ? 140.158 125.294 107.294 1.00 54.25  ? 229 PHE R CD2 1 
ATOM 1475 C CE1 . PHE A 1 285 ? 142.536 124.003 107.778 1.00 53.37  ? 229 PHE R CE1 1 
ATOM 1476 C CE2 . PHE A 1 285 ? 140.838 125.525 108.472 1.00 51.91  ? 229 PHE R CE2 1 
ATOM 1477 C CZ  . PHE A 1 285 ? 142.028 124.878 108.714 1.00 51.50  ? 229 PHE R CZ  1 
ATOM 1478 N N   . CYS A 1 286 ? 138.039 122.368 106.698 1.00 56.97  ? 230 CYS R N   1 
ATOM 1479 C CA  . CYS A 1 286 ? 137.664 121.833 108.001 1.00 48.45  ? 230 CYS R CA  1 
ATOM 1480 C C   . CYS A 1 286 ? 137.450 120.326 107.941 1.00 53.10  ? 230 CYS R C   1 
ATOM 1481 O O   . CYS A 1 286 ? 137.972 119.581 108.779 1.00 53.96  ? 230 CYS R O   1 
ATOM 1482 C CB  . CYS A 1 286 ? 136.404 122.536 108.505 1.00 41.75  ? 230 CYS R CB  1 
ATOM 1483 S SG  . CYS A 1 286 ? 136.651 124.268 108.953 1.00 55.16  ? 230 CYS R SG  1 
ATOM 1484 N N   . TYR A 1 287 ? 136.699 119.853 106.946 1.00 54.44  ? 231 TYR R N   1 
ATOM 1485 C CA  . TYR A 1 287 ? 136.392 118.433 106.884 1.00 45.64  ? 231 TYR R CA  1 
ATOM 1486 C C   . TYR A 1 287 ? 137.587 117.608 106.430 1.00 54.36  ? 231 TYR R C   1 
ATOM 1487 O O   . TYR A 1 287 ? 137.710 116.452 106.836 1.00 63.35  ? 231 TYR R O   1 
ATOM 1488 C CB  . TYR A 1 287 ? 135.190 118.192 105.973 1.00 41.98  ? 231 TYR R CB  1 
ATOM 1489 C CG  . TYR A 1 287 ? 133.868 118.435 106.667 1.00 47.22  ? 231 TYR R CG  1 
ATOM 1490 C CD1 . TYR A 1 287 ? 133.529 117.739 107.818 1.00 49.85  ? 231 TYR R CD1 1 
ATOM 1491 C CD2 . TYR A 1 287 ? 132.958 119.355 106.171 1.00 54.08  ? 231 TYR R CD2 1 
ATOM 1492 C CE1 . TYR A 1 287 ? 132.325 117.955 108.456 1.00 48.90  ? 231 TYR R CE1 1 
ATOM 1493 C CE2 . TYR A 1 287 ? 131.750 119.577 106.802 1.00 48.58  ? 231 TYR R CE2 1 
ATOM 1494 C CZ  . TYR A 1 287 ? 131.440 118.874 107.943 1.00 44.86  ? 231 TYR R CZ  1 
ATOM 1495 O OH  . TYR A 1 287 ? 130.239 119.091 108.575 1.00 47.59  ? 231 TYR R OH  1 
ATOM 1496 N N   . GLY A 1 288 ? 138.492 118.173 105.627 1.00 54.16  ? 232 GLY R N   1 
ATOM 1497 C CA  . GLY A 1 288 ? 139.718 117.460 105.313 1.00 59.25  ? 232 GLY R CA  1 
ATOM 1498 C C   . GLY A 1 288 ? 140.585 117.247 106.537 1.00 58.07  ? 232 GLY R C   1 
ATOM 1499 O O   . GLY A 1 288 ? 141.086 116.143 106.778 1.00 56.41  ? 232 GLY R O   1 
ATOM 1500 N N   . PHE A 1 289 ? 140.764 118.300 107.341 1.00 54.50  ? 233 PHE R N   1 
ATOM 1501 C CA  . PHE A 1 289 ? 141.548 118.131 108.562 1.00 57.41  ? 233 PHE R CA  1 
ATOM 1502 C C   . PHE A 1 289 ? 140.849 117.202 109.551 1.00 59.93  ? 233 PHE R C   1 
ATOM 1503 O O   . PHE A 1 289 ? 141.507 116.404 110.231 1.00 62.92  ? 233 PHE R O   1 
ATOM 1504 C CB  . PHE A 1 289 ? 141.855 119.486 109.200 1.00 59.43  ? 233 PHE R CB  1 
ATOM 1505 C CG  . PHE A 1 289 ? 142.961 120.248 108.513 1.00 64.21  ? 233 PHE R CG  1 
ATOM 1506 C CD1 . PHE A 1 289 ? 143.190 120.105 107.153 1.00 64.26  ? 233 PHE R CD1 1 
ATOM 1507 C CD2 . PHE A 1 289 ? 143.791 121.086 109.238 1.00 61.49  ? 233 PHE R CD2 1 
ATOM 1508 C CE1 . PHE A 1 289 ? 144.210 120.797 106.528 1.00 61.97  ? 233 PHE R CE1 1 
ATOM 1509 C CE2 . PHE A 1 289 ? 144.816 121.778 108.617 1.00 64.32  ? 233 PHE R CE2 1 
ATOM 1510 C CZ  . PHE A 1 289 ? 145.023 121.634 107.260 1.00 60.75  ? 233 PHE R CZ  1 
ATOM 1511 N N   . THR A 1 290 ? 139.518 117.276 109.637 1.00 54.94  ? 234 THR R N   1 
ATOM 1512 C CA  . THR A 1 290 ? 138.785 116.370 110.516 1.00 50.87  ? 234 THR R CA  1 
ATOM 1513 C C   . THR A 1 290 ? 138.925 114.922 110.059 1.00 58.00  ? 234 THR R C   1 
ATOM 1514 O O   . THR A 1 290 ? 139.074 114.013 110.885 1.00 62.08  ? 234 THR R O   1 
ATOM 1515 C CB  . THR A 1 290 ? 137.312 116.775 110.575 1.00 48.08  ? 234 THR R CB  1 
ATOM 1516 O OG1 . THR A 1 290 ? 137.201 118.092 111.126 1.00 48.89  ? 234 THR R OG1 1 
ATOM 1517 C CG2 . THR A 1 290 ? 136.531 115.812 111.445 1.00 52.18  ? 234 THR R CG2 1 
ATOM 1518 N N   . LEU A 1 291 ? 138.877 114.686 108.746 1.00 56.84  ? 235 LEU R N   1 
ATOM 1519 C CA  . LEU A 1 291 ? 139.067 113.339 108.223 1.00 56.20  ? 235 LEU R CA  1 
ATOM 1520 C C   . LEU A 1 291 ? 140.472 112.833 108.511 1.00 65.35  ? 235 LEU R C   1 
ATOM 1521 O O   . LEU A 1 291 ? 140.657 111.659 108.851 1.00 70.07  ? 235 LEU R O   1 
ATOM 1522 C CB  . LEU A 1 291 ? 138.787 113.313 106.721 1.00 56.34  ? 235 LEU R CB  1 
ATOM 1523 C CG  . LEU A 1 291 ? 137.321 113.207 106.301 1.00 62.28  ? 235 LEU R CG  1 
ATOM 1524 C CD1 . LEU A 1 291 ? 137.164 113.530 104.823 1.00 62.57  ? 235 LEU R CD1 1 
ATOM 1525 C CD2 . LEU A 1 291 ? 136.773 111.824 106.614 1.00 61.72  ? 235 LEU R CD2 1 
ATOM 1526 N N   . ARG A 1 292 ? 141.479 113.700 108.370 1.00 67.65  ? 236 ARG R N   1 
ATOM 1527 C CA  . ARG A 1 292 ? 142.840 113.290 108.705 1.00 67.08  ? 236 ARG R CA  1 
ATOM 1528 C C   . ARG A 1 292 ? 142.947 112.916 110.178 1.00 68.31  ? 236 ARG R C   1 
ATOM 1529 O O   . ARG A 1 292 ? 143.570 111.906 110.526 1.00 69.25  ? 236 ARG R O   1 
ATOM 1530 C CB  . ARG A 1 292 ? 143.832 114.402 108.352 1.00 66.39  ? 236 ARG R CB  1 
ATOM 1531 C CG  . ARG A 1 292 ? 145.291 114.107 108.719 1.00 64.29  ? 236 ARG R CG  1 
ATOM 1532 C CD  . ARG A 1 292 ? 145.666 114.612 110.110 1.00 68.33  ? 236 ARG R CD  1 
ATOM 1533 N NE  . ARG A 1 292 ? 147.072 114.383 110.421 1.00 74.25  ? 236 ARG R NE  1 
ATOM 1534 C CZ  . ARG A 1 292 ? 147.624 114.610 111.606 1.00 71.74  ? 236 ARG R CZ  1 
ATOM 1535 N NH1 . ARG A 1 292 ? 146.912 115.065 112.624 1.00 66.40  ? 236 ARG R NH1 1 
ATOM 1536 N NH2 . ARG A 1 292 ? 148.921 114.372 111.773 1.00 67.56  ? 236 ARG R NH2 1 
ATOM 1537 N N   . THR A 1 293 ? 142.347 113.721 111.058 1.00 67.42  ? 237 THR R N   1 
ATOM 1538 C CA  . THR A 1 293 ? 142.397 113.424 112.487 1.00 64.37  ? 237 THR R CA  1 
ATOM 1539 C C   . THR A 1 293 ? 141.699 112.105 112.805 1.00 66.12  ? 237 THR R C   1 
ATOM 1540 O O   . THR A 1 293 ? 142.222 111.287 113.571 1.00 67.46  ? 237 THR R O   1 
ATOM 1541 C CB  . THR A 1 293 ? 141.772 114.571 113.281 1.00 65.14  ? 237 THR R CB  1 
ATOM 1542 O OG1 . THR A 1 293 ? 142.729 115.626 113.429 1.00 66.58  ? 237 THR R OG1 1 
ATOM 1543 C CG2 . THR A 1 293 ? 141.331 114.099 114.657 1.00 66.52  ? 237 THR R CG2 1 
ATOM 1544 N N   . LEU A 1 294 ? 140.523 111.877 112.217 1.00 71.31  ? 238 LEU R N   1 
ATOM 1545 C CA  . LEU A 1 294 ? 139.805 110.626 112.450 1.00 72.46  ? 238 LEU R CA  1 
ATOM 1546 C C   . LEU A 1 294 ? 140.580 109.429 111.914 1.00 75.57  ? 238 LEU R C   1 
ATOM 1547 O O   . LEU A 1 294 ? 140.557 108.348 112.513 1.00 78.68  ? 238 LEU R O   1 
ATOM 1548 C CB  . LEU A 1 294 ? 138.418 110.685 111.809 1.00 69.21  ? 238 LEU R CB  1 
ATOM 1549 C CG  . LEU A 1 294 ? 137.336 111.478 112.538 1.00 68.01  ? 238 LEU R CG  1 
ATOM 1550 C CD1 . LEU A 1 294 ? 136.351 112.070 111.551 1.00 72.06  ? 238 LEU R CD1 1 
ATOM 1551 C CD2 . LEU A 1 294 ? 136.621 110.573 113.511 1.00 67.12  ? 238 LEU R CD2 1 
ATOM 1552 N N   . PHE A 1 295 ? 141.268 109.603 110.783 1.00 82.32  ? 239 PHE R N   1 
ATOM 1553 C CA  . PHE A 1 295 ? 141.913 108.476 110.117 1.00 84.24  ? 239 PHE R CA  1 
ATOM 1554 C C   . PHE A 1 295 ? 143.009 107.865 110.983 1.00 87.74  ? 239 PHE R C   1 
ATOM 1555 O O   . PHE A 1 295 ? 143.177 106.640 111.011 1.00 89.33  ? 239 PHE R O   1 
ATOM 1556 C CB  . PHE A 1 295 ? 142.473 108.924 108.766 1.00 81.54  ? 239 PHE R CB  1 
ATOM 1557 C CG  . PHE A 1 295 ? 142.872 107.789 107.868 1.00 86.26  ? 239 PHE R CG  1 
ATOM 1558 C CD1 . PHE A 1 295 ? 141.957 107.229 106.994 1.00 87.21  ? 239 PHE R CD1 1 
ATOM 1559 C CD2 . PHE A 1 295 ? 144.163 107.289 107.890 1.00 88.30  ? 239 PHE R CD2 1 
ATOM 1560 C CE1 . PHE A 1 295 ? 142.319 106.185 106.164 1.00 87.42  ? 239 PHE R CE1 1 
ATOM 1561 C CE2 . PHE A 1 295 ? 144.531 106.245 107.062 1.00 86.47  ? 239 PHE R CE2 1 
ATOM 1562 C CZ  . PHE A 1 295 ? 143.608 105.693 106.198 1.00 88.57  ? 239 PHE R CZ  1 
ATOM 1563 N N   . LYS A 1 296 ? 143.761 108.699 111.704 1.00 92.74  ? 240 LYS R N   1 
ATOM 1564 C CA  . LYS A 1 296 ? 144.882 108.240 112.515 1.00 95.89  ? 240 LYS R CA  1 
ATOM 1565 C C   . LYS A 1 296 ? 144.496 107.993 113.970 1.00 98.75  ? 240 LYS R C   1 
ATOM 1566 O O   . LYS A 1 296 ? 145.330 108.173 114.868 1.00 101.71 ? 240 LYS R O   1 
ATOM 1567 C CB  . LYS A 1 296 ? 146.034 109.243 112.432 1.00 93.46  ? 240 LYS R CB  1 
ATOM 1568 N N   . ALA A 1 297 ? 143.255 107.589 114.228 1.00 92.45  ? 241 ALA R N   1 
ATOM 1569 C CA  . ALA A 1 297 ? 142.774 107.316 115.573 1.00 92.86  ? 241 ALA R CA  1 
ATOM 1570 C C   . ALA A 1 297 ? 142.237 105.892 115.650 1.00 93.57  ? 241 ALA R C   1 
ATOM 1571 O O   . ALA A 1 297 ? 141.935 105.265 114.632 1.00 92.56  ? 241 ALA R O   1 
ATOM 1572 C CB  . ALA A 1 297 ? 141.692 108.317 115.986 1.00 94.31  ? 241 ALA R CB  1 
ATOM 1573 N N   . HIS A 1 298 ? 142.124 105.381 116.875 1.00 92.39  ? 242 HIS R N   1 
ATOM 1574 C CA  . HIS A 1 298 ? 141.827 103.972 117.117 1.00 92.44  ? 242 HIS R CA  1 
ATOM 1575 C C   . HIS A 1 298 ? 140.497 103.758 117.838 1.00 88.72  ? 242 HIS R C   1 
ATOM 1576 O O   . HIS A 1 298 ? 140.389 102.906 118.721 1.00 79.75  ? 242 HIS R O   1 
ATOM 1577 C CB  . HIS A 1 298 ? 142.959 103.317 117.903 1.00 88.08  ? 242 HIS R CB  1 
ATOM 1578 C CG  . HIS A 1 298 ? 144.229 103.174 117.125 1.00 91.89  ? 242 HIS R CG  1 
ATOM 1579 N ND1 . HIS A 1 298 ? 144.259 102.708 115.828 1.00 89.33  ? 242 HIS R ND1 1 
ATOM 1580 C CD2 . HIS A 1 298 ? 145.515 103.436 117.460 1.00 92.04  ? 242 HIS R CD2 1 
ATOM 1581 C CE1 . HIS A 1 298 ? 145.508 102.689 115.398 1.00 88.35  ? 242 HIS R CE1 1 
ATOM 1582 N NE2 . HIS A 1 298 ? 146.290 103.126 116.369 1.00 91.87  ? 242 HIS R NE2 1 
ATOM 1583 N N   . MET A 1 299 ? 139.467 104.519 117.473 1.00 87.52  ? 243 MET R N   1 
ATOM 1584 C CA  . MET A 1 299 ? 138.136 104.251 117.997 1.00 83.68  ? 243 MET R CA  1 
ATOM 1585 C C   . MET A 1 299 ? 137.535 103.030 117.304 1.00 90.18  ? 243 MET R C   1 
ATOM 1586 O O   . MET A 1 299 ? 138.156 102.385 116.456 1.00 93.49  ? 243 MET R O   1 
ATOM 1587 C CB  . MET A 1 299 ? 137.216 105.457 117.816 1.00 83.59  ? 243 MET R CB  1 
ATOM 1588 C CG  . MET A 1 299 ? 137.681 106.733 118.478 1.00 85.26  ? 243 MET R CG  1 
ATOM 1589 S SD  . MET A 1 299 ? 138.581 107.809 117.356 1.00 84.51  ? 243 MET R SD  1 
ATOM 1590 C CE  . MET A 1 299 ? 137.270 108.284 116.238 1.00 86.88  ? 243 MET R CE  1 
ATOM 1591 N N   . GLY A 1 300 ? 136.301 102.709 117.680 1.00 101.04 ? 244 GLY R N   1 
ATOM 1592 C CA  . GLY A 1 300 ? 135.558 101.663 117.010 1.00 99.47  ? 244 GLY R CA  1 
ATOM 1593 C C   . GLY A 1 300 ? 134.472 102.210 116.108 1.00 98.64  ? 244 GLY R C   1 
ATOM 1594 O O   . GLY A 1 300 ? 133.825 101.454 115.376 1.00 97.21  ? 244 GLY R O   1 
ATOM 1595 N N   . GLN A 1 301 ? 134.263 103.525 116.149 1.00 92.37  ? 245 GLN R N   1 
ATOM 1596 C CA  . GLN A 1 301 ? 133.192 104.184 115.409 1.00 91.09  ? 245 GLN R CA  1 
ATOM 1597 C C   . GLN A 1 301 ? 133.744 105.291 114.521 1.00 93.78  ? 245 GLN R C   1 
ATOM 1598 O O   . GLN A 1 301 ? 133.118 106.339 114.343 1.00 100.78 ? 245 GLN R O   1 
ATOM 1599 C CB  . GLN A 1 301 ? 132.134 104.740 116.358 1.00 92.01  ? 245 GLN R CB  1 
ATOM 1600 C CG  . GLN A 1 301 ? 131.877 103.883 117.586 1.00 91.03  ? 245 GLN R CG  1 
ATOM 1601 C CD  . GLN A 1 301 ? 132.625 104.378 118.807 1.00 94.82  ? 245 GLN R CD  1 
ATOM 1602 O OE1 . GLN A 1 301 ? 132.530 105.549 119.174 1.00 95.81  ? 245 GLN R OE1 1 
ATOM 1603 N NE2 . GLN A 1 301 ? 133.370 103.485 119.448 1.00 93.64  ? 245 GLN R NE2 1 
ATOM 1604 N N   . LYS A 1 302 ? 134.930 105.077 113.953 1.00 87.43  ? 246 LYS R N   1 
ATOM 1605 C CA  . LYS A 1 302 ? 135.507 106.055 113.037 1.00 90.69  ? 246 LYS R CA  1 
ATOM 1606 C C   . LYS A 1 302 ? 134.844 106.003 111.663 1.00 95.19  ? 246 LYS R C   1 
ATOM 1607 O O   . LYS A 1 302 ? 134.653 107.045 111.017 1.00 100.44 ? 246 LYS R O   1 
ATOM 1608 C CB  . LYS A 1 302 ? 137.013 105.816 112.918 1.00 91.49  ? 246 LYS R CB  1 
ATOM 1609 C CG  . LYS A 1 302 ? 137.376 104.371 112.590 1.00 94.18  ? 246 LYS R CG  1 
ATOM 1610 C CD  . LYS A 1 302 ? 138.850 104.063 112.823 1.00 94.97  ? 246 LYS R CD  1 
ATOM 1611 C CE  . LYS A 1 302 ? 139.741 105.208 112.384 1.00 96.73  ? 246 LYS R CE  1 
ATOM 1612 N NZ  . LYS A 1 302 ? 141.163 104.790 112.249 1.00 94.46  ? 246 LYS R NZ  1 
ATOM 1613 N N   . HIS A 1 303 ? 134.479 104.800 111.210 1.00 92.84  ? 247 HIS R N   1 
ATOM 1614 C CA  . HIS A 1 303 ? 133.977 104.630 109.851 1.00 92.74  ? 247 HIS R CA  1 
ATOM 1615 C C   . HIS A 1 303 ? 132.662 105.369 109.646 1.00 94.60  ? 247 HIS R C   1 
ATOM 1616 O O   . HIS A 1 303 ? 132.454 105.994 108.600 1.00 98.10  ? 247 HIS R O   1 
ATOM 1617 C CB  . HIS A 1 303 ? 133.813 103.144 109.531 1.00 93.34  ? 247 HIS R CB  1 
ATOM 1618 C CG  . HIS A 1 303 ? 135.022 102.317 109.843 1.00 96.92  ? 247 HIS R CG  1 
ATOM 1619 N ND1 . HIS A 1 303 ? 135.465 102.098 111.130 1.00 98.47  ? 247 HIS R ND1 1 
ATOM 1620 C CD2 . HIS A 1 303 ? 135.885 101.660 109.032 1.00 96.86  ? 247 HIS R CD2 1 
ATOM 1621 C CE1 . HIS A 1 303 ? 136.546 101.338 111.099 1.00 94.64  ? 247 HIS R CE1 1 
ATOM 1622 N NE2 . HIS A 1 303 ? 136.822 101.059 109.838 1.00 95.10  ? 247 HIS R NE2 1 
ATOM 1623 N N   . ARG A 1 304 ? 131.760 105.307 110.629 1.00 85.72  ? 248 ARG R N   1 
ATOM 1624 C CA  . ARG A 1 304 ? 130.501 106.036 110.512 1.00 89.82  ? 248 ARG R CA  1 
ATOM 1625 C C   . ARG A 1 304 ? 130.737 107.539 110.463 1.00 90.73  ? 248 ARG R C   1 
ATOM 1626 O O   . ARG A 1 304 ? 130.050 108.257 109.727 1.00 92.74  ? 248 ARG R O   1 
ATOM 1627 C CB  . ARG A 1 304 ? 129.566 105.679 111.665 1.00 89.41  ? 248 ARG R CB  1 
ATOM 1628 C CG  . ARG A 1 304 ? 128.146 106.196 111.474 1.00 88.02  ? 248 ARG R CG  1 
ATOM 1629 C CD  . ARG A 1 304 ? 127.109 105.193 111.947 1.00 90.88  ? 248 ARG R CD  1 
ATOM 1630 N NE  . ARG A 1 304 ? 125.784 105.485 111.413 1.00 91.35  ? 248 ARG R NE  1 
ATOM 1631 C CZ  . ARG A 1 304 ? 124.649 105.240 112.052 1.00 90.50  ? 248 ARG R CZ  1 
ATOM 1632 N NH1 . ARG A 1 304 ? 124.637 104.695 113.257 1.00 88.31  ? 248 ARG R NH1 1 
ATOM 1633 N NH2 . ARG A 1 304 ? 123.495 105.550 111.467 1.00 87.92  ? 248 ARG R NH2 1 
ATOM 1634 N N   . ALA A 1 305 ? 131.696 108.037 111.245 1.00 79.56  ? 249 ALA R N   1 
ATOM 1635 C CA  . ALA A 1 305 ? 131.997 109.464 111.223 1.00 73.39  ? 249 ALA R CA  1 
ATOM 1636 C C   . ALA A 1 305 ? 132.488 109.899 109.848 1.00 75.51  ? 249 ALA R C   1 
ATOM 1637 O O   . ALA A 1 305 ? 132.030 110.913 109.302 1.00 80.41  ? 249 ALA R O   1 
ATOM 1638 C CB  . ALA A 1 305 ? 133.032 109.798 112.296 1.00 77.25  ? 249 ALA R CB  1 
ATOM 1639 N N   . MET A 1 306 ? 133.417 109.134 109.262 1.00 74.02  ? 250 MET R N   1 
ATOM 1640 C CA  . MET A 1 306 ? 133.884 109.480 107.922 1.00 75.49  ? 250 MET R CA  1 
ATOM 1641 C C   . MET A 1 306 ? 132.761 109.378 106.897 1.00 78.42  ? 250 MET R C   1 
ATOM 1642 O O   . MET A 1 306 ? 132.668 110.210 105.987 1.00 81.27  ? 250 MET R O   1 
ATOM 1643 C CB  . MET A 1 306 ? 135.066 108.604 107.508 1.00 78.29  ? 250 MET R CB  1 
ATOM 1644 C CG  . MET A 1 306 ? 136.112 108.382 108.577 1.00 76.72  ? 250 MET R CG  1 
ATOM 1645 S SD  . MET A 1 306 ? 137.087 106.906 108.248 1.00 85.97  ? 250 MET R SD  1 
ATOM 1646 C CE  . MET A 1 306 ? 138.143 106.883 109.687 1.00 75.32  ? 250 MET R CE  1 
ATOM 1647 N N   . ARG A 1 307 ? 131.901 108.364 107.023 1.00 74.84  ? 251 ARG R N   1 
ATOM 1648 C CA  . ARG A 1 307 ? 130.787 108.226 106.091 1.00 75.63  ? 251 ARG R CA  1 
ATOM 1649 C C   . ARG A 1 307 ? 129.853 109.426 106.167 1.00 76.82  ? 251 ARG R C   1 
ATOM 1650 O O   . ARG A 1 307 ? 129.433 109.959 105.135 1.00 76.92  ? 251 ARG R O   1 
ATOM 1651 C CB  . ARG A 1 307 ? 130.021 106.933 106.370 1.00 76.14  ? 251 ARG R CB  1 
ATOM 1652 C CG  . ARG A 1 307 ? 128.576 106.955 105.893 1.00 78.70  ? 251 ARG R CG  1 
ATOM 1653 C CD  . ARG A 1 307 ? 128.011 105.550 105.739 1.00 82.07  ? 251 ARG R CD  1 
ATOM 1654 N NE  . ARG A 1 307 ? 127.318 105.094 106.939 1.00 81.39  ? 251 ARG R NE  1 
ATOM 1655 C CZ  . ARG A 1 307 ? 126.117 105.511 107.319 1.00 82.45  ? 251 ARG R CZ  1 
ATOM 1656 N NH1 . ARG A 1 307 ? 125.437 106.400 106.613 1.00 77.84  ? 251 ARG R NH1 1 
ATOM 1657 N NH2 . ARG A 1 307 ? 125.584 105.022 108.434 1.00 80.16  ? 251 ARG R NH2 1 
ATOM 1658 N N   . VAL A 1 308 ? 129.526 109.872 107.382 1.00 70.02  ? 252 VAL R N   1 
ATOM 1659 C CA  . VAL A 1 308 ? 128.633 111.017 107.540 1.00 61.99  ? 252 VAL R CA  1 
ATOM 1660 C C   . VAL A 1 308 ? 129.272 112.281 106.977 1.00 67.58  ? 252 VAL R C   1 
ATOM 1661 O O   . VAL A 1 308 ? 128.610 113.076 106.299 1.00 71.81  ? 252 VAL R O   1 
ATOM 1662 C CB  . VAL A 1 308 ? 128.243 111.192 109.018 1.00 64.27  ? 252 VAL R CB  1 
ATOM 1663 C CG1 . VAL A 1 308 ? 127.452 112.472 109.207 1.00 66.45  ? 252 VAL R CG1 1 
ATOM 1664 C CG2 . VAL A 1 308 ? 127.441 109.998 109.499 1.00 68.37  ? 252 VAL R CG2 1 
ATOM 1665 N N   . ILE A 1 309 ? 130.563 112.492 107.252 1.00 65.71  ? 253 ILE R N   1 
ATOM 1666 C CA  . ILE A 1 309 ? 131.245 113.681 106.741 1.00 58.05  ? 253 ILE R CA  1 
ATOM 1667 C C   . ILE A 1 309 ? 131.242 113.683 105.215 1.00 61.83  ? 253 ILE R C   1 
ATOM 1668 O O   . ILE A 1 309 ? 130.932 114.699 104.572 1.00 69.19  ? 253 ILE R O   1 
ATOM 1669 C CB  . ILE A 1 309 ? 132.676 113.752 107.304 1.00 63.00  ? 253 ILE R CB  1 
ATOM 1670 C CG1 . ILE A 1 309 ? 132.659 114.311 108.726 1.00 64.92  ? 253 ILE R CG1 1 
ATOM 1671 C CG2 . ILE A 1 309 ? 133.572 114.579 106.397 1.00 62.57  ? 253 ILE R CG2 1 
ATOM 1672 C CD1 . ILE A 1 309 ? 133.970 114.153 109.453 1.00 59.99  ? 253 ILE R CD1 1 
ATOM 1673 N N   . PHE A 1 310 ? 131.584 112.541 104.613 1.00 58.64  ? 254 PHE R N   1 
ATOM 1674 C CA  . PHE A 1 310 ? 131.607 112.450 103.159 1.00 59.58  ? 254 PHE R CA  1 
ATOM 1675 C C   . PHE A 1 310 ? 130.217 112.652 102.575 1.00 59.04  ? 254 PHE R C   1 
ATOM 1676 O O   . PHE A 1 310 ? 130.065 113.301 101.534 1.00 66.01  ? 254 PHE R O   1 
ATOM 1677 C CB  . PHE A 1 310 ? 132.184 111.104 102.725 1.00 64.02  ? 254 PHE R CB  1 
ATOM 1678 C CG  . PHE A 1 310 ? 133.626 111.169 102.317 1.00 69.71  ? 254 PHE R CG  1 
ATOM 1679 C CD1 . PHE A 1 310 ? 134.067 112.148 101.443 1.00 64.08  ? 254 PHE R CD1 1 
ATOM 1680 C CD2 . PHE A 1 310 ? 134.542 110.255 102.811 1.00 68.12  ? 254 PHE R CD2 1 
ATOM 1681 C CE1 . PHE A 1 310 ? 135.394 112.213 101.068 1.00 66.19  ? 254 PHE R CE1 1 
ATOM 1682 C CE2 . PHE A 1 310 ? 135.870 110.314 102.440 1.00 64.53  ? 254 PHE R CE2 1 
ATOM 1683 C CZ  . PHE A 1 310 ? 136.297 111.294 101.567 1.00 66.75  ? 254 PHE R CZ  1 
ATOM 1684 N N   . ALA A 1 311 ? 129.191 112.104 103.228 1.00 52.78  ? 255 ALA R N   1 
ATOM 1685 C CA  . ALA A 1 311 ? 127.827 112.298 102.752 1.00 55.69  ? 255 ALA R CA  1 
ATOM 1686 C C   . ALA A 1 311 ? 127.433 113.767 102.794 1.00 52.81  ? 255 ALA R C   1 
ATOM 1687 O O   . ALA A 1 311 ? 126.811 114.274 101.856 1.00 56.92  ? 255 ALA R O   1 
ATOM 1688 C CB  . ALA A 1 311 ? 126.855 111.457 103.579 1.00 60.84  ? 255 ALA R CB  1 
ATOM 1689 N N   . VAL A 1 312 ? 127.790 114.469 103.872 1.00 53.54  ? 256 VAL R N   1 
ATOM 1690 C CA  . VAL A 1 312 ? 127.460 115.889 103.975 1.00 50.48  ? 256 VAL R CA  1 
ATOM 1691 C C   . VAL A 1 312 ? 128.125 116.670 102.848 1.00 53.67  ? 256 VAL R C   1 
ATOM 1692 O O   . VAL A 1 312 ? 127.487 117.487 102.169 1.00 53.49  ? 256 VAL R O   1 
ATOM 1693 C CB  . VAL A 1 312 ? 127.870 116.438 105.354 1.00 47.65  ? 256 VAL R CB  1 
ATOM 1694 C CG1 . VAL A 1 312 ? 127.812 117.956 105.358 1.00 52.36  ? 256 VAL R CG1 1 
ATOM 1695 C CG2 . VAL A 1 312 ? 126.985 115.863 106.443 1.00 47.94  ? 256 VAL R CG2 1 
ATOM 1696 N N   . VAL A 1 313 ? 129.418 116.418 102.625 1.00 54.45  ? 257 VAL R N   1 
ATOM 1697 C CA  . VAL A 1 313 ? 130.139 117.156 101.589 1.00 51.24  ? 257 VAL R CA  1 
ATOM 1698 C C   . VAL A 1 313 ? 129.565 116.851 100.209 1.00 52.96  ? 257 VAL R C   1 
ATOM 1699 O O   . VAL A 1 313 ? 129.353 117.759 99.391  1.00 55.87  ? 257 VAL R O   1 
ATOM 1700 C CB  . VAL A 1 313 ? 131.645 116.846 101.659 1.00 52.62  ? 257 VAL R CB  1 
ATOM 1701 C CG1 . VAL A 1 313 ? 132.388 117.592 100.565 1.00 56.96  ? 257 VAL R CG1 1 
ATOM 1702 C CG2 . VAL A 1 313 ? 132.196 117.223 103.021 1.00 52.69  ? 257 VAL R CG2 1 
ATOM 1703 N N   . LEU A 1 314 ? 129.298 115.572 99.929  1.00 51.06  ? 258 LEU R N   1 
ATOM 1704 C CA  . LEU A 1 314 ? 128.768 115.193 98.624  1.00 51.06  ? 258 LEU R CA  1 
ATOM 1705 C C   . LEU A 1 314 ? 127.381 115.775 98.395  1.00 56.50  ? 258 LEU R C   1 
ATOM 1706 O O   . LEU A 1 314 ? 127.061 116.200 97.282  1.00 59.50  ? 258 LEU R O   1 
ATOM 1707 C CB  . LEU A 1 314 ? 128.740 113.673 98.487  1.00 51.90  ? 258 LEU R CB  1 
ATOM 1708 C CG  . LEU A 1 314 ? 130.103 113.008 98.297  1.00 62.61  ? 258 LEU R CG  1 
ATOM 1709 C CD1 . LEU A 1 314 ? 129.984 111.496 98.391  1.00 59.78  ? 258 LEU R CD1 1 
ATOM 1710 C CD2 . LEU A 1 314 ? 130.713 113.423 96.969  1.00 55.21  ? 258 LEU R CD2 1 
ATOM 1711 N N   . ILE A 1 315 ? 126.537 115.794 99.429  1.00 60.60  ? 259 ILE R N   1 
ATOM 1712 C CA  . ILE A 1 315 ? 125.208 116.372 99.274  1.00 53.92  ? 259 ILE R CA  1 
ATOM 1713 C C   . ILE A 1 315 ? 125.302 117.867 99.008  1.00 56.30  ? 259 ILE R C   1 
ATOM 1714 O O   . ILE A 1 315 ? 124.598 118.396 98.140  1.00 57.42  ? 259 ILE R O   1 
ATOM 1715 C CB  . ILE A 1 315 ? 124.333 116.071 100.502 1.00 51.03  ? 259 ILE R CB  1 
ATOM 1716 C CG1 . ILE A 1 315 ? 123.996 114.581 100.561 1.00 53.26  ? 259 ILE R CG1 1 
ATOM 1717 C CG2 . ILE A 1 315 ? 123.065 116.904 100.459 1.00 52.77  ? 259 ILE R CG2 1 
ATOM 1718 C CD1 . ILE A 1 315 ? 123.003 114.137 99.515  1.00 55.19  ? 259 ILE R CD1 1 
ATOM 1719 N N   . PHE A 1 316 ? 126.168 118.576 99.738  1.00 57.30  ? 260 PHE R N   1 
ATOM 1720 C CA  . PHE A 1 316 ? 126.311 120.009 99.495  1.00 52.22  ? 260 PHE R CA  1 
ATOM 1721 C C   . PHE A 1 316 ? 126.773 120.274 98.067  1.00 53.95  ? 260 PHE R C   1 
ATOM 1722 O O   . PHE A 1 316 ? 126.233 121.152 97.375  1.00 55.42  ? 260 PHE R O   1 
ATOM 1723 C CB  . PHE A 1 316 ? 127.286 120.625 100.499 1.00 53.74  ? 260 PHE R CB  1 
ATOM 1724 C CG  . PHE A 1 316 ? 127.546 122.090 100.271 1.00 51.93  ? 260 PHE R CG  1 
ATOM 1725 C CD1 . PHE A 1 316 ? 126.735 123.047 100.852 1.00 53.82  ? 260 PHE R CD1 1 
ATOM 1726 C CD2 . PHE A 1 316 ? 128.606 122.508 99.485  1.00 53.15  ? 260 PHE R CD2 1 
ATOM 1727 C CE1 . PHE A 1 316 ? 126.971 124.392 100.647 1.00 55.22  ? 260 PHE R CE1 1 
ATOM 1728 C CE2 . PHE A 1 316 ? 128.844 123.851 99.276  1.00 54.93  ? 260 PHE R CE2 1 
ATOM 1729 C CZ  . PHE A 1 316 ? 128.026 124.794 99.858  1.00 52.31  ? 260 PHE R CZ  1 
ATOM 1730 N N   . LEU A 1 317 ? 127.769 119.514 97.604  1.00 54.66  ? 261 LEU R N   1 
ATOM 1731 C CA  . LEU A 1 317 ? 128.257 119.698 96.241  1.00 57.59  ? 261 LEU R CA  1 
ATOM 1732 C C   . LEU A 1 317 ? 127.164 119.399 95.223  1.00 63.69  ? 261 LEU R C   1 
ATOM 1733 O O   . LEU A 1 317 ? 126.862 120.231 94.361  1.00 68.27  ? 261 LEU R O   1 
ATOM 1734 C CB  . LEU A 1 317 ? 129.482 118.818 95.999  1.00 59.44  ? 261 LEU R CB  1 
ATOM 1735 C CG  . LEU A 1 317 ? 130.816 119.432 96.423  1.00 59.58  ? 261 LEU R CG  1 
ATOM 1736 C CD1 . LEU A 1 317 ? 131.963 118.480 96.133  1.00 61.64  ? 261 LEU R CD1 1 
ATOM 1737 C CD2 . LEU A 1 317 ? 131.030 120.764 95.722  1.00 55.87  ? 261 LEU R CD2 1 
ATOM 1738 N N   . LEU A 1 318 ? 126.534 118.226 95.330  1.00 57.99  ? 262 LEU R N   1 
ATOM 1739 C CA  . LEU A 1 318 ? 125.475 117.847 94.402  1.00 56.59  ? 262 LEU R CA  1 
ATOM 1740 C C   . LEU A 1 318 ? 124.359 118.882 94.375  1.00 59.11  ? 262 LEU R C   1 
ATOM 1741 O O   . LEU A 1 318 ? 123.769 119.145 93.321  1.00 59.58  ? 262 LEU R O   1 
ATOM 1742 C CB  . LEU A 1 318 ? 124.927 116.470 94.784  1.00 53.33  ? 262 LEU R CB  1 
ATOM 1743 C CG  . LEU A 1 318 ? 123.626 115.972 94.150  1.00 55.97  ? 262 LEU R CG  1 
ATOM 1744 C CD1 . LEU A 1 318 ? 123.742 114.499 93.805  1.00 57.01  ? 262 LEU R CD1 1 
ATOM 1745 C CD2 . LEU A 1 318 ? 122.444 116.200 95.083  1.00 50.60  ? 262 LEU R CD2 1 
ATOM 1746 N N   . CYS A 1 319 ? 124.057 119.484 95.526  1.00 64.54  ? 263 CYS R N   1 
ATOM 1747 C CA  . CYS A 1 319 ? 122.959 120.438 95.590  1.00 62.95  ? 263 CYS R CA  1 
ATOM 1748 C C   . CYS A 1 319 ? 123.319 121.776 94.957  1.00 61.51  ? 263 CYS R C   1 
ATOM 1749 O O   . CYS A 1 319 ? 122.512 122.341 94.212  1.00 61.99  ? 263 CYS R O   1 
ATOM 1750 C CB  . CYS A 1 319 ? 122.526 120.638 97.043  1.00 65.03  ? 263 CYS R CB  1 
ATOM 1751 S SG  . CYS A 1 319 ? 121.438 119.343 97.680  1.00 66.14  ? 263 CYS R SG  1 
ATOM 1752 N N   . TRP A 1 320 ? 124.518 122.303 95.219  1.00 63.54  ? 264 TRP R N   1 
ATOM 1753 C CA  . TRP A 1 320 ? 124.775 123.696 94.875  1.00 68.57  ? 264 TRP R CA  1 
ATOM 1754 C C   . TRP A 1 320 ? 125.766 123.916 93.738  1.00 67.83  ? 264 TRP R C   1 
ATOM 1755 O O   . TRP A 1 320 ? 125.839 125.039 93.227  1.00 66.95  ? 264 TRP R O   1 
ATOM 1756 C CB  . TRP A 1 320 ? 125.249 124.466 96.116  1.00 72.03  ? 264 TRP R CB  1 
ATOM 1757 C CG  . TRP A 1 320 ? 124.108 124.949 96.964  1.00 67.58  ? 264 TRP R CG  1 
ATOM 1758 C CD1 . TRP A 1 320 ? 123.856 124.620 98.262  1.00 64.48  ? 264 TRP R CD1 1 
ATOM 1759 C CD2 . TRP A 1 320 ? 123.056 125.837 96.564  1.00 66.70  ? 264 TRP R CD2 1 
ATOM 1760 N NE1 . TRP A 1 320 ? 122.717 125.250 98.699  1.00 60.65  ? 264 TRP R NE1 1 
ATOM 1761 C CE2 . TRP A 1 320 ? 122.207 126.004 97.675  1.00 62.94  ? 264 TRP R CE2 1 
ATOM 1762 C CE3 . TRP A 1 320 ? 122.751 126.510 95.377  1.00 69.77  ? 264 TRP R CE3 1 
ATOM 1763 C CZ2 . TRP A 1 320 ? 121.075 126.813 97.634  1.00 67.78  ? 264 TRP R CZ2 1 
ATOM 1764 C CZ3 . TRP A 1 320 ? 121.626 127.312 95.339  1.00 66.09  ? 264 TRP R CZ3 1 
ATOM 1765 C CH2 . TRP A 1 320 ? 120.803 127.458 96.460  1.00 67.05  ? 264 TRP R CH2 1 
ATOM 1766 N N   . LEU A 1 321 ? 126.532 122.900 93.325  1.00 69.91  ? 265 LEU R N   1 
ATOM 1767 C CA  . LEU A 1 321 ? 127.479 123.105 92.228  1.00 71.46  ? 265 LEU R CA  1 
ATOM 1768 C C   . LEU A 1 321 ? 126.798 123.406 90.897  1.00 76.94  ? 265 LEU R C   1 
ATOM 1769 O O   . LEU A 1 321 ? 127.220 124.360 90.217  1.00 82.58  ? 265 LEU R O   1 
ATOM 1770 C CB  . LEU A 1 321 ? 128.414 121.898 92.121  1.00 70.29  ? 265 LEU R CB  1 
ATOM 1771 C CG  . LEU A 1 321 ? 129.586 122.058 91.155  1.00 68.08  ? 265 LEU R CG  1 
ATOM 1772 C CD1 . LEU A 1 321 ? 130.613 123.017 91.727  1.00 68.73  ? 265 LEU R CD1 1 
ATOM 1773 C CD2 . LEU A 1 321 ? 130.213 120.709 90.853  1.00 72.03  ? 265 LEU R CD2 1 
ATOM 1774 N N   . PRO A 1 322 ? 125.788 122.645 90.444  1.00 76.52  ? 266 PRO R N   1 
ATOM 1775 C CA  . PRO A 1 322 ? 125.223 122.925 89.110  1.00 77.72  ? 266 PRO R CA  1 
ATOM 1776 C C   . PRO A 1 322 ? 124.653 124.325 88.964  1.00 73.48  ? 266 PRO R C   1 
ATOM 1777 O O   . PRO A 1 322 ? 124.792 124.934 87.896  1.00 70.71  ? 266 PRO R O   1 
ATOM 1778 C CB  . PRO A 1 322 ? 124.136 121.850 88.962  1.00 72.92  ? 266 PRO R CB  1 
ATOM 1779 C CG  . PRO A 1 322 ? 124.552 120.765 89.878  1.00 72.91  ? 266 PRO R CG  1 
ATOM 1780 C CD  . PRO A 1 322 ? 125.151 121.463 91.053  1.00 70.02  ? 266 PRO R CD  1 
ATOM 1781 N N   . TYR A 1 323 ? 124.019 124.856 90.011  1.00 77.56  ? 267 TYR R N   1 
ATOM 1782 C CA  . TYR A 1 323 ? 123.470 126.206 89.935  1.00 77.17  ? 267 TYR R CA  1 
ATOM 1783 C C   . TYR A 1 323 ? 124.572 127.229 89.695  1.00 82.78  ? 267 TYR R C   1 
ATOM 1784 O O   . TYR A 1 323 ? 124.446 128.107 88.833  1.00 91.98  ? 267 TYR R O   1 
ATOM 1785 C CB  . TYR A 1 323 ? 122.701 126.530 91.216  1.00 83.60  ? 267 TYR R CB  1 
ATOM 1786 C CG  . TYR A 1 323 ? 122.047 127.892 91.213  1.00 82.13  ? 267 TYR R CG  1 
ATOM 1787 C CD1 . TYR A 1 323 ? 120.913 128.136 90.452  1.00 82.08  ? 267 TYR R CD1 1 
ATOM 1788 C CD2 . TYR A 1 323 ? 122.564 128.933 91.970  1.00 83.21  ? 267 TYR R CD2 1 
ATOM 1789 C CE1 . TYR A 1 323 ? 120.309 129.379 90.448  1.00 82.81  ? 267 TYR R CE1 1 
ATOM 1790 C CE2 . TYR A 1 323 ? 121.970 130.179 91.971  1.00 83.48  ? 267 TYR R CE2 1 
ATOM 1791 C CZ  . TYR A 1 323 ? 120.843 130.397 91.208  1.00 86.10  ? 267 TYR R CZ  1 
ATOM 1792 O OH  . TYR A 1 323 ? 120.247 131.637 91.205  1.00 87.58  ? 267 TYR R OH  1 
ATOM 1793 N N   . ASN A 1 324 ? 125.673 127.118 90.441  1.00 76.34  ? 268 ASN R N   1 
ATOM 1794 C CA  . ASN A 1 324 ? 126.769 128.066 90.278  1.00 75.35  ? 268 ASN R CA  1 
ATOM 1795 C C   . ASN A 1 324 ? 127.446 127.906 88.925  1.00 76.72  ? 268 ASN R C   1 
ATOM 1796 O O   . ASN A 1 324 ? 127.855 128.898 88.311  1.00 78.77  ? 268 ASN R O   1 
ATOM 1797 C CB  . ASN A 1 324 ? 127.776 127.905 91.412  1.00 74.70  ? 268 ASN R CB  1 
ATOM 1798 C CG  . ASN A 1 324 ? 127.419 128.737 92.622  1.00 78.17  ? 268 ASN R CG  1 
ATOM 1799 O OD1 . ASN A 1 324 ? 128.118 129.689 92.961  1.00 79.85  ? 268 ASN R OD1 1 
ATOM 1800 N ND2 . ASN A 1 324 ? 126.319 128.387 93.277  1.00 74.51  ? 268 ASN R ND2 1 
ATOM 1801 N N   . LEU A 1 325 ? 127.574 126.668 88.439  1.00 77.83  ? 269 LEU R N   1 
ATOM 1802 C CA  . LEU A 1 325 ? 128.155 126.463 87.114  1.00 81.65  ? 269 LEU R CA  1 
ATOM 1803 C C   . LEU A 1 325 ? 127.291 127.095 86.028  1.00 85.77  ? 269 LEU R C   1 
ATOM 1804 O O   . LEU A 1 325 ? 127.808 127.755 85.116  1.00 83.52  ? 269 LEU R O   1 
ATOM 1805 C CB  . LEU A 1 325 ? 128.350 124.971 86.851  1.00 79.40  ? 269 LEU R CB  1 
ATOM 1806 C CG  . LEU A 1 325 ? 129.585 124.342 87.497  1.00 81.00  ? 269 LEU R CG  1 
ATOM 1807 C CD1 . LEU A 1 325 ? 129.709 122.878 87.112  1.00 84.18  ? 269 LEU R CD1 1 
ATOM 1808 C CD2 . LEU A 1 325 ? 130.841 125.108 87.117  1.00 78.54  ? 269 LEU R CD2 1 
ATOM 1809 N N   . VAL A 1 326 ? 125.971 126.919 86.118  1.00 87.04  ? 270 VAL R N   1 
ATOM 1810 C CA  . VAL A 1 326 ? 125.071 127.513 85.133  1.00 81.20  ? 270 VAL R CA  1 
ATOM 1811 C C   . VAL A 1 326 ? 125.127 129.033 85.204  1.00 79.05  ? 270 VAL R C   1 
ATOM 1812 O O   . VAL A 1 326 ? 125.122 129.717 84.173  1.00 81.58  ? 270 VAL R O   1 
ATOM 1813 C CB  . VAL A 1 326 ? 123.637 126.987 85.330  1.00 78.83  ? 270 VAL R CB  1 
ATOM 1814 C CG1 . VAL A 1 326 ? 122.659 127.782 84.484  1.00 78.31  ? 270 VAL R CG1 1 
ATOM 1815 C CG2 . VAL A 1 326 ? 123.566 125.514 84.972  1.00 83.63  ? 270 VAL R CG2 1 
ATOM 1816 N N   . LEU A 1 327 ? 125.178 129.589 86.416  1.00 86.36  ? 271 LEU R N   1 
ATOM 1817 C CA  . LEU A 1 327 ? 125.251 131.041 86.552  1.00 87.24  ? 271 LEU R CA  1 
ATOM 1818 C C   . LEU A 1 327 ? 126.559 131.589 85.991  1.00 86.49  ? 271 LEU R C   1 
ATOM 1819 O O   . LEU A 1 327 ? 126.571 132.650 85.354  1.00 91.72  ? 271 LEU R O   1 
ATOM 1820 C CB  . LEU A 1 327 ? 125.074 131.443 88.015  1.00 86.27  ? 271 LEU R CB  1 
ATOM 1821 C CG  . LEU A 1 327 ? 123.645 131.792 88.442  1.00 87.67  ? 271 LEU R CG  1 
ATOM 1822 C CD1 . LEU A 1 327 ? 123.165 133.039 87.724  1.00 89.52  ? 271 LEU R CD1 1 
ATOM 1823 C CD2 . LEU A 1 327 ? 122.687 130.641 88.190  1.00 87.81  ? 271 LEU R CD2 1 
ATOM 1824 N N   . LEU A 1 328 ? 127.672 130.889 86.222  1.00 89.79  ? 272 LEU R N   1 
ATOM 1825 C CA  . LEU A 1 328 ? 128.943 131.312 85.641  1.00 93.41  ? 272 LEU R CA  1 
ATOM 1826 C C   . LEU A 1 328 ? 128.896 131.255 84.120  1.00 92.77  ? 272 LEU R C   1 
ATOM 1827 O O   . LEU A 1 328 ? 129.407 132.154 83.441  1.00 94.12  ? 272 LEU R O   1 
ATOM 1828 C CB  . LEU A 1 328 ? 130.084 130.448 86.177  1.00 93.99  ? 272 LEU R CB  1 
ATOM 1829 N N   . ALA A 1 329 ? 128.284 130.206 83.565  1.00 92.88  ? 273 ALA R N   1 
ATOM 1830 C CA  . ALA A 1 329 ? 128.138 130.127 82.114  1.00 95.30  ? 273 ALA R CA  1 
ATOM 1831 C C   . ALA A 1 329 ? 127.282 131.272 81.585  1.00 97.43  ? 273 ALA R C   1 
ATOM 1832 O O   . ALA A 1 329 ? 127.573 131.840 80.525  1.00 96.52  ? 273 ALA R O   1 
ATOM 1833 C CB  . ALA A 1 329 ? 127.539 128.779 81.718  1.00 95.01  ? 273 ALA R CB  1 
ATOM 1834 N N   . ASP A 1 330 ? 126.218 131.623 82.310  1.00 101.73 ? 274 ASP R N   1 
ATOM 1835 C CA  . ASP A 1 330 ? 125.368 132.739 81.901  1.00 99.59  ? 274 ASP R CA  1 
ATOM 1836 C C   . ASP A 1 330 ? 126.148 134.048 81.906  1.00 95.04  ? 274 ASP R C   1 
ATOM 1837 O O   . ASP A 1 330 ? 126.054 134.847 80.966  1.00 95.46  ? 274 ASP R O   1 
ATOM 1838 C CB  . ASP A 1 330 ? 124.151 132.827 82.823  1.00 97.92  ? 274 ASP R CB  1 
ATOM 1839 C CG  . ASP A 1 330 ? 123.093 133.790 82.314  1.00 99.93  ? 274 ASP R CG  1 
ATOM 1840 O OD1 . ASP A 1 330 ? 123.283 134.382 81.232  1.00 103.30 ? 274 ASP R OD1 1 
ATOM 1841 O OD2 . ASP A 1 330 ? 122.063 133.952 83.001  1.00 100.45 ? 274 ASP R OD2 1 
ATOM 1842 N N   . THR A 1 331 ? 126.933 134.281 82.962  1.00 95.85  ? 275 THR R N   1 
ATOM 1843 C CA  . THR A 1 331 ? 127.749 135.489 83.018  1.00 98.44  ? 275 THR R CA  1 
ATOM 1844 C C   . THR A 1 331 ? 128.775 135.514 81.894  1.00 101.73 ? 275 THR R C   1 
ATOM 1845 O O   . THR A 1 331 ? 129.066 136.581 81.341  1.00 104.79 ? 275 THR R O   1 
ATOM 1846 C CB  . THR A 1 331 ? 128.444 135.600 84.376  1.00 97.84  ? 275 THR R CB  1 
ATOM 1847 O OG1 . THR A 1 331 ? 127.463 135.561 85.418  1.00 101.40 ? 275 THR R OG1 1 
ATOM 1848 C CG2 . THR A 1 331 ? 129.217 136.906 84.476  1.00 95.15  ? 275 THR R CG2 1 
ATOM 1849 N N   . LEU A 1 332 ? 129.329 134.353 81.541  1.00 104.71 ? 276 LEU R N   1 
ATOM 1850 C CA  . LEU A 1 332 ? 130.240 134.286 80.403  1.00 104.05 ? 276 LEU R CA  1 
ATOM 1851 C C   . LEU A 1 332 ? 129.524 134.631 79.102  1.00 106.16 ? 276 LEU R C   1 
ATOM 1852 O O   . LEU A 1 332 ? 130.090 135.311 78.238  1.00 104.76 ? 276 LEU R O   1 
ATOM 1853 C CB  . LEU A 1 332 ? 130.873 132.898 80.318  1.00 101.94 ? 276 LEU R CB  1 
ATOM 1854 C CG  . LEU A 1 332 ? 132.037 132.634 81.275  1.00 103.49 ? 276 LEU R CG  1 
ATOM 1855 C CD1 . LEU A 1 332 ? 132.802 131.389 80.859  1.00 104.21 ? 276 LEU R CD1 1 
ATOM 1856 C CD2 . LEU A 1 332 ? 132.963 133.837 81.339  1.00 103.99 ? 276 LEU R CD2 1 
ATOM 1857 N N   . MET A 1 333 ? 128.283 134.165 78.941  1.00 106.60 ? 277 MET R N   1 
ATOM 1858 C CA  . MET A 1 333 ? 127.526 134.486 77.733  1.00 105.68 ? 277 MET R CA  1 
ATOM 1859 C C   . MET A 1 333 ? 127.243 135.980 77.636  1.00 106.91 ? 277 MET R C   1 
ATOM 1860 O O   . MET A 1 333 ? 127.418 136.588 76.574  1.00 107.90 ? 277 MET R O   1 
ATOM 1861 C CB  . MET A 1 333 ? 126.218 133.694 77.689  1.00 102.95 ? 277 MET R CB  1 
ATOM 1862 C CG  . MET A 1 333 ? 125.177 134.326 76.771  1.00 104.62 ? 277 MET R CG  1 
ATOM 1863 S SD  . MET A 1 333 ? 123.583 133.491 76.739  1.00 109.63 ? 277 MET R SD  1 
ATOM 1864 C CE  . MET A 1 333 ? 124.105 131.783 76.740  1.00 108.47 ? 277 MET R CE  1 
ATOM 1865 N N   . ARG A 1 334 ? 126.804 136.594 78.739  1.00 101.58 ? 278 ARG R N   1 
ATOM 1866 C CA  . ARG A 1 334 ? 126.518 138.025 78.706  1.00 99.71  ? 278 ARG R CA  1 
ATOM 1867 C C   . ARG A 1 334 ? 127.770 138.858 78.471  1.00 102.17 ? 278 ARG R C   1 
ATOM 1868 O O   . ARG A 1 334 ? 127.665 139.989 77.985  1.00 105.10 ? 278 ARG R O   1 
ATOM 1869 C CB  . ARG A 1 334 ? 125.829 138.466 79.998  1.00 99.44  ? 278 ARG R CB  1 
ATOM 1870 C CG  . ARG A 1 334 ? 124.654 137.593 80.405  1.00 101.94 ? 278 ARG R CG  1 
ATOM 1871 C CD  . ARG A 1 334 ? 123.449 138.427 80.814  1.00 102.63 ? 278 ARG R CD  1 
ATOM 1872 N NE  . ARG A 1 334 ? 122.664 138.859 79.663  1.00 104.70 ? 278 ARG R NE  1 
ATOM 1873 C CZ  . ARG A 1 334 ? 121.883 138.064 78.942  1.00 102.91 ? 278 ARG R CZ  1 
ATOM 1874 N NH1 . ARG A 1 334 ? 121.746 136.781 79.232  1.00 101.15 ? 278 ARG R NH1 1 
ATOM 1875 N NH2 . ARG A 1 334 ? 121.221 138.571 77.906  1.00 98.59  ? 278 ARG R NH2 1 
ATOM 1876 N N   . THR A 1 335 ? 128.946 138.327 78.796  1.00 103.32 ? 279 THR R N   1 
ATOM 1877 C CA  . THR A 1 335 ? 130.208 139.001 78.529  1.00 104.08 ? 279 THR R CA  1 
ATOM 1878 C C   . THR A 1 335 ? 130.709 138.742 77.110  1.00 107.39 ? 279 THR R C   1 
ATOM 1879 O O   . THR A 1 335 ? 131.709 139.341 76.697  1.00 110.08 ? 279 THR R O   1 
ATOM 1880 C CB  . THR A 1 335 ? 131.256 138.553 79.560  1.00 105.17 ? 279 THR R CB  1 
ATOM 1881 O OG1 . THR A 1 335 ? 130.676 138.598 80.869  1.00 104.32 ? 279 THR R OG1 1 
ATOM 1882 C CG2 . THR A 1 335 ? 132.468 139.480 79.560  1.00 108.48 ? 279 THR R CG2 1 
ATOM 1883 N N   . GLN A 1 336 ? 130.023 137.879 76.357  1.00 108.92 ? 280 GLN R N   1 
ATOM 1884 C CA  . GLN A 1 336 ? 130.362 137.511 74.984  1.00 109.81 ? 280 GLN R CA  1 
ATOM 1885 C C   . GLN A 1 336 ? 131.671 136.736 74.886  1.00 109.80 ? 280 GLN R C   1 
ATOM 1886 O O   . GLN A 1 336 ? 132.249 136.632 73.799  1.00 109.24 ? 280 GLN R O   1 
ATOM 1887 C CB  . GLN A 1 336 ? 130.409 138.738 74.063  1.00 107.94 ? 280 GLN R CB  1 
ATOM 1888 N N   . VAL A 1 337 ? 132.157 136.188 76.002  1.00 107.02 ? 281 VAL R N   1 
ATOM 1889 C CA  . VAL A 1 337 ? 133.326 135.317 75.949  1.00 107.77 ? 281 VAL R CA  1 
ATOM 1890 C C   . VAL A 1 337 ? 133.005 134.043 75.177  1.00 109.10 ? 281 VAL R C   1 
ATOM 1891 O O   . VAL A 1 337 ? 133.790 133.596 74.331  1.00 111.17 ? 281 VAL R O   1 
ATOM 1892 C CB  . VAL A 1 337 ? 133.827 135.010 77.371  1.00 107.88 ? 281 VAL R CB  1 
ATOM 1893 C CG1 . VAL A 1 337 ? 134.964 134.000 77.330  1.00 108.86 ? 281 VAL R CG1 1 
ATOM 1894 C CG2 . VAL A 1 337 ? 134.268 136.289 78.064  1.00 106.91 ? 281 VAL R CG2 1 
ATOM 1895 N N   . ILE A 1 338 ? 131.849 133.445 75.448  1.00 114.02 ? 282 ILE R N   1 
ATOM 1896 C CA  . ILE A 1 338 ? 131.376 132.258 74.745  1.00 115.07 ? 282 ILE R CA  1 
ATOM 1897 C C   . ILE A 1 338 ? 130.343 132.693 73.716  1.00 116.29 ? 282 ILE R C   1 
ATOM 1898 O O   . ILE A 1 338 ? 129.487 133.541 74.001  1.00 115.33 ? 282 ILE R O   1 
ATOM 1899 C CB  . ILE A 1 338 ? 130.791 131.226 75.729  1.00 115.16 ? 282 ILE R CB  1 
ATOM 1900 C CG1 . ILE A 1 338 ? 129.975 130.163 74.990  1.00 114.90 ? 282 ILE R CG1 1 
ATOM 1901 C CG2 . ILE A 1 338 ? 129.941 131.914 76.785  1.00 115.20 ? 282 ILE R CG2 1 
ATOM 1902 C CD1 . ILE A 1 338 ? 129.728 128.910 75.803  1.00 114.72 ? 282 ILE R CD1 1 
ATOM 1903 N N   . GLN A 1 339 ? 130.435 132.130 72.511  1.00 126.14 ? 283 GLN R N   1 
ATOM 1904 C CA  . GLN A 1 339 ? 129.547 132.524 71.425  1.00 126.66 ? 283 GLN R CA  1 
ATOM 1905 C C   . GLN A 1 339 ? 128.087 132.327 71.817  1.00 126.51 ? 283 GLN R C   1 
ATOM 1906 O O   . GLN A 1 339 ? 127.716 131.314 72.417  1.00 125.68 ? 283 GLN R O   1 
ATOM 1907 C CB  . GLN A 1 339 ? 129.867 131.725 70.162  1.00 125.49 ? 283 GLN R CB  1 
ATOM 1908 C CG  . GLN A 1 339 ? 129.252 132.300 68.897  1.00 125.09 ? 283 GLN R CG  1 
ATOM 1909 C CD  . GLN A 1 339 ? 130.125 132.084 67.678  1.00 125.84 ? 283 GLN R CD  1 
ATOM 1910 O OE1 . GLN A 1 339 ? 131.179 131.453 67.758  1.00 127.07 ? 283 GLN R OE1 1 
ATOM 1911 N NE2 . GLN A 1 339 ? 129.691 132.612 66.539  1.00 124.65 ? 283 GLN R NE2 1 
ATOM 1912 N N   . GLU A 1 340 ? 127.260 133.308 71.473  1.00 129.74 ? 284 GLU R N   1 
ATOM 1913 C CA  . GLU A 1 340 ? 125.867 133.361 71.894  1.00 129.44 ? 284 GLU R CA  1 
ATOM 1914 C C   . GLU A 1 340 ? 124.954 133.033 70.722  1.00 128.50 ? 284 GLU R C   1 
ATOM 1915 O O   . GLU A 1 340 ? 125.057 133.650 69.656  1.00 129.58 ? 284 GLU R O   1 
ATOM 1916 C CB  . GLU A 1 340 ? 125.528 134.743 72.457  1.00 129.88 ? 284 GLU R CB  1 
ATOM 1917 C CG  . GLU A 1 340 ? 124.144 134.850 73.070  1.00 129.89 ? 284 GLU R CG  1 
ATOM 1918 C CD  . GLU A 1 340 ? 123.934 136.166 73.791  1.00 128.92 ? 284 GLU R CD  1 
ATOM 1919 O OE1 . GLU A 1 340 ? 124.894 136.961 73.867  1.00 126.94 ? 284 GLU R OE1 1 
ATOM 1920 O OE2 . GLU A 1 340 ? 122.810 136.406 74.279  1.00 129.66 ? 284 GLU R OE2 1 
ATOM 1921 N N   . THR A 1 341 ? 124.065 132.063 70.923  1.00 132.97 ? 285 THR R N   1 
ATOM 1922 C CA  . THR A 1 341 ? 123.046 131.703 69.949  1.00 134.46 ? 285 THR R CA  1 
ATOM 1923 C C   . THR A 1 341 ? 121.715 131.535 70.668  1.00 134.56 ? 285 THR R C   1 
ATOM 1924 O O   . THR A 1 341 ? 121.668 131.299 71.878  1.00 135.08 ? 285 THR R O   1 
ATOM 1925 C CB  . THR A 1 341 ? 123.394 130.411 69.191  1.00 134.48 ? 285 THR R CB  1 
ATOM 1926 O OG1 . THR A 1 341 ? 123.451 129.314 70.111  1.00 135.57 ? 285 THR R OG1 1 
ATOM 1927 C CG2 . THR A 1 341 ? 124.731 130.543 68.474  1.00 133.64 ? 285 THR R CG2 1 
ATOM 1928 N N   . CYS A 1 342 ? 120.627 131.663 69.904  1.00 135.16 ? 286 CYS R N   1 
ATOM 1929 C CA  . CYS A 1 342 ? 119.294 131.538 70.486  1.00 136.54 ? 286 CYS R CA  1 
ATOM 1930 C C   . CYS A 1 342 ? 119.098 130.170 71.128  1.00 134.35 ? 286 CYS R C   1 
ATOM 1931 O O   . CYS A 1 342 ? 118.478 130.056 72.194  1.00 132.37 ? 286 CYS R O   1 
ATOM 1932 C CB  . CYS A 1 342 ? 118.230 131.789 69.417  1.00 138.24 ? 286 CYS R CB  1 
ATOM 1933 S SG  . CYS A 1 342 ? 116.525 131.725 70.018  1.00 145.90 ? 286 CYS R SG  1 
ATOM 1934 N N   . GLU A 1 343 ? 119.624 129.120 70.495  1.00 132.95 ? 287 GLU R N   1 
ATOM 1935 C CA  . GLU A 1 343 ? 119.556 127.789 71.089  1.00 134.35 ? 287 GLU R CA  1 
ATOM 1936 C C   . GLU A 1 343 ? 120.310 127.742 72.412  1.00 135.05 ? 287 GLU R C   1 
ATOM 1937 O O   . GLU A 1 343 ? 119.841 127.132 73.379  1.00 135.46 ? 287 GLU R O   1 
ATOM 1938 C CB  . GLU A 1 343 ? 120.110 126.749 70.115  1.00 133.57 ? 287 GLU R CB  1 
ATOM 1939 N N   . ARG A 1 344 ? 121.479 128.385 72.473  1.00 129.95 ? 288 ARG R N   1 
ATOM 1940 C CA  . ARG A 1 344 ? 122.223 128.448 73.727  1.00 129.02 ? 288 ARG R CA  1 
ATOM 1941 C C   . ARG A 1 344 ? 121.446 129.213 74.791  1.00 127.49 ? 288 ARG R C   1 
ATOM 1942 O O   . ARG A 1 344 ? 121.439 128.826 75.967  1.00 125.49 ? 288 ARG R O   1 
ATOM 1943 C CB  . ARG A 1 344 ? 123.590 129.091 73.494  1.00 128.39 ? 288 ARG R CB  1 
ATOM 1944 C CG  . ARG A 1 344 ? 124.652 128.675 74.497  1.00 127.26 ? 288 ARG R CG  1 
ATOM 1945 C CD  . ARG A 1 344 ? 126.001 128.497 73.824  1.00 127.32 ? 288 ARG R CD  1 
ATOM 1946 N NE  . ARG A 1 344 ? 126.102 127.214 73.140  1.00 127.49 ? 288 ARG R NE  1 
ATOM 1947 C CZ  . ARG A 1 344 ? 126.577 126.106 73.693  1.00 128.36 ? 288 ARG R CZ  1 
ATOM 1948 N NH1 . ARG A 1 344 ? 127.008 126.088 74.944  1.00 128.39 ? 288 ARG R NH1 1 
ATOM 1949 N NH2 . ARG A 1 344 ? 126.621 124.989 72.974  1.00 128.24 ? 288 ARG R NH2 1 
ATOM 1950 N N   . ARG A 1 345 ? 120.792 130.310 74.397  1.00 129.18 ? 289 ARG R N   1 
ATOM 1951 C CA  . ARG A 1 345 ? 119.985 131.072 75.343  1.00 129.84 ? 289 ARG R CA  1 
ATOM 1952 C C   . ARG A 1 345 ? 118.861 130.218 75.913  1.00 130.08 ? 289 ARG R C   1 
ATOM 1953 O O   . ARG A 1 345 ? 118.634 130.203 77.128  1.00 129.57 ? 289 ARG R O   1 
ATOM 1954 C CB  . ARG A 1 345 ? 119.419 132.322 74.666  1.00 129.91 ? 289 ARG R CB  1 
ATOM 1955 C CG  . ARG A 1 345 ? 120.472 133.254 74.089  1.00 129.39 ? 289 ARG R CG  1 
ATOM 1956 C CD  . ARG A 1 345 ? 119.846 134.285 73.162  1.00 129.07 ? 289 ARG R CD  1 
ATOM 1957 N NE  . ARG A 1 345 ? 119.937 135.637 73.699  1.00 127.63 ? 289 ARG R NE  1 
ATOM 1958 C CZ  . ARG A 1 345 ? 119.239 136.670 73.247  1.00 130.09 ? 289 ARG R CZ  1 
ATOM 1959 N NH1 . ARG A 1 345 ? 118.383 136.540 72.246  1.00 130.86 ? 289 ARG R NH1 1 
ATOM 1960 N NH2 . ARG A 1 345 ? 119.402 137.862 73.813  1.00 130.72 ? 289 ARG R NH2 1 
ATOM 1961 N N   . ASN A 1 346 ? 118.155 129.483 75.049  1.00 128.99 ? 290 ASN R N   1 
ATOM 1962 C CA  . ASN A 1 346 ? 117.085 128.609 75.523  1.00 129.02 ? 290 ASN R CA  1 
ATOM 1963 C C   . ASN A 1 346 ? 117.629 127.510 76.430  1.00 128.92 ? 290 ASN R C   1 
ATOM 1964 O O   . ASN A 1 346 ? 117.031 127.194 77.469  1.00 129.26 ? 290 ASN R O   1 
ATOM 1965 C CB  . ASN A 1 346 ? 116.340 128.001 74.335  1.00 129.57 ? 290 ASN R CB  1 
ATOM 1966 C CG  . ASN A 1 346 ? 115.085 128.772 73.977  1.00 130.09 ? 290 ASN R CG  1 
ATOM 1967 O OD1 . ASN A 1 346 ? 114.620 129.615 74.744  1.00 130.53 ? 290 ASN R OD1 1 
ATOM 1968 N ND2 . ASN A 1 346 ? 114.528 128.484 72.806  1.00 129.08 ? 290 ASN R ND2 1 
ATOM 1969 N N   . HIS A 1 347 ? 118.763 126.916 76.050  1.00 124.41 ? 291 HIS R N   1 
ATOM 1970 C CA  . HIS A 1 347 ? 119.348 125.840 76.842  1.00 124.85 ? 291 HIS R CA  1 
ATOM 1971 C C   . HIS A 1 347 ? 119.702 126.323 78.241  1.00 123.88 ? 291 HIS R C   1 
ATOM 1972 O O   . HIS A 1 347 ? 119.362 125.677 79.239  1.00 123.25 ? 291 HIS R O   1 
ATOM 1973 C CB  . HIS A 1 347 ? 120.589 125.288 76.140  1.00 124.51 ? 291 HIS R CB  1 
ATOM 1974 C CG  . HIS A 1 347 ? 120.290 124.532 74.883  1.00 125.15 ? 291 HIS R CG  1 
ATOM 1975 N ND1 . HIS A 1 347 ? 121.266 124.196 73.969  1.00 124.72 ? 291 HIS R ND1 1 
ATOM 1976 C CD2 . HIS A 1 347 ? 119.127 124.051 74.386  1.00 124.56 ? 291 HIS R CD2 1 
ATOM 1977 C CE1 . HIS A 1 347 ? 120.716 123.539 72.964  1.00 125.75 ? 291 HIS R CE1 1 
ATOM 1978 N NE2 . HIS A 1 347 ? 119.419 123.437 73.192  1.00 125.63 ? 291 HIS R NE2 1 
ATOM 1979 N N   . ILE A 1 348 ? 120.384 127.467 78.333  1.00 112.40 ? 292 ILE R N   1 
ATOM 1980 C CA  . ILE A 1 348 ? 120.775 127.983 79.641  1.00 112.95 ? 292 ILE R CA  1 
ATOM 1981 C C   . ILE A 1 348 ? 119.553 128.441 80.428  1.00 110.97 ? 292 ILE R C   1 
ATOM 1982 O O   . ILE A 1 348 ? 119.494 128.274 81.651  1.00 111.60 ? 292 ILE R O   1 
ATOM 1983 C CB  . ILE A 1 348 ? 121.830 129.096 79.491  1.00 112.85 ? 292 ILE R CB  1 
ATOM 1984 C CG1 . ILE A 1 348 ? 123.230 128.478 79.490  1.00 109.59 ? 292 ILE R CG1 1 
ATOM 1985 C CG2 . ILE A 1 348 ? 121.707 130.136 80.594  1.00 112.82 ? 292 ILE R CG2 1 
ATOM 1986 C CD1 . ILE A 1 348 ? 124.350 129.476 79.375  1.00 107.15 ? 292 ILE R CD1 1 
ATOM 1987 N N   . ASP A 1 349 ? 118.547 128.999 79.748  1.00 112.83 ? 293 ASP R N   1 
ATOM 1988 C CA  . ASP A 1 349 ? 117.339 129.427 80.446  1.00 113.90 ? 293 ASP R CA  1 
ATOM 1989 C C   . ASP A 1 349 ? 116.623 128.245 81.090  1.00 115.83 ? 293 ASP R C   1 
ATOM 1990 O O   . ASP A 1 349 ? 116.129 128.351 82.218  1.00 116.36 ? 293 ASP R O   1 
ATOM 1991 C CB  . ASP A 1 349 ? 116.410 130.158 79.477  1.00 116.42 ? 293 ASP R CB  1 
ATOM 1992 C CG  . ASP A 1 349 ? 115.502 131.151 80.178  1.00 117.72 ? 293 ASP R CG  1 
ATOM 1993 O OD1 . ASP A 1 349 ? 115.296 131.012 81.402  1.00 119.00 ? 293 ASP R OD1 1 
ATOM 1994 O OD2 . ASP A 1 349 ? 114.994 132.072 79.503  1.00 117.15 ? 293 ASP R OD2 1 
ATOM 1995 N N   . ARG A 1 350 ? 116.550 127.112 80.387  1.00 113.56 ? 294 ARG R N   1 
ATOM 1996 C CA  . ARG A 1 350 ? 115.915 125.931 80.971  1.00 111.09 ? 294 ARG R CA  1 
ATOM 1997 C C   . ARG A 1 350 ? 116.790 125.305 82.054  1.00 116.55 ? 294 ARG R C   1 
ATOM 1998 O O   . ARG A 1 350 ? 116.288 124.887 83.111  1.00 115.99 ? 294 ARG R O   1 
ATOM 1999 C CB  . ARG A 1 350 ? 115.600 124.914 79.875  1.00 111.13 ? 294 ARG R CB  1 
ATOM 2000 C CG  . ARG A 1 350 ? 114.501 123.931 80.235  1.00 113.59 ? 294 ARG R CG  1 
ATOM 2001 C CD  . ARG A 1 350 ? 114.710 122.595 79.541  1.00 114.32 ? 294 ARG R CD  1 
ATOM 2002 N NE  . ARG A 1 350 ? 115.215 122.758 78.184  1.00 115.62 ? 294 ARG R NE  1 
ATOM 2003 C CZ  . ARG A 1 350 ? 114.534 122.451 77.088  1.00 115.83 ? 294 ARG R CZ  1 
ATOM 2004 N NH1 . ARG A 1 350 ? 113.307 121.962 77.152  1.00 113.58 ? 294 ARG R NH1 1 
ATOM 2005 N NH2 . ARG A 1 350 ? 115.099 122.639 75.899  1.00 116.09 ? 294 ARG R NH2 1 
ATOM 2006 N N   . ALA A 1 351 ? 118.103 125.233 81.810  1.00 108.95 ? 295 ALA R N   1 
ATOM 2007 C CA  . ALA A 1 351 ? 119.012 124.637 82.779  1.00 101.93 ? 295 ALA R CA  1 
ATOM 2008 C C   . ALA A 1 351 ? 119.067 125.440 84.070  1.00 101.76 ? 295 ALA R C   1 
ATOM 2009 O O   . ALA A 1 351 ? 119.287 124.866 85.139  1.00 102.33 ? 295 ALA R O   1 
ATOM 2010 C CB  . ALA A 1 351 ? 120.410 124.505 82.177  1.00 101.28 ? 295 ALA R CB  1 
ATOM 2011 N N   . LEU A 1 352 ? 118.871 126.757 83.995  1.00 98.33  ? 296 LEU R N   1 
ATOM 2012 C CA  . LEU A 1 352 ? 118.851 127.573 85.203  1.00 96.14  ? 296 LEU R CA  1 
ATOM 2013 C C   . LEU A 1 352 ? 117.700 127.168 86.113  1.00 96.20  ? 296 LEU R C   1 
ATOM 2014 O O   . LEU A 1 352 ? 117.882 126.990 87.322  1.00 96.30  ? 296 LEU R O   1 
ATOM 2015 C CB  . LEU A 1 352 ? 118.753 129.053 84.830  1.00 95.16  ? 296 LEU R CB  1 
ATOM 2016 C CG  . LEU A 1 352 ? 119.407 130.062 85.775  1.00 97.59  ? 296 LEU R CG  1 
ATOM 2017 C CD1 . LEU A 1 352 ? 119.775 131.326 85.016  1.00 100.65 ? 296 LEU R CD1 1 
ATOM 2018 C CD2 . LEU A 1 352 ? 118.493 130.388 86.945  1.00 96.83  ? 296 LEU R CD2 1 
ATOM 2019 N N   . ASP A 1 353 ? 116.503 127.009 85.543  1.00 98.84  ? 297 ASP R N   1 
ATOM 2020 C CA  . ASP A 1 353 ? 115.360 126.568 86.335  1.00 99.28  ? 297 ASP R CA  1 
ATOM 2021 C C   . ASP A 1 353 ? 115.585 125.163 86.880  1.00 101.24 ? 297 ASP R C   1 
ATOM 2022 O O   . ASP A 1 353 ? 115.280 124.884 88.049  1.00 102.33 ? 297 ASP R O   1 
ATOM 2023 C CB  . ASP A 1 353 ? 114.088 126.626 85.488  1.00 101.79 ? 297 ASP R CB  1 
ATOM 2024 C CG  . ASP A 1 353 ? 112.821 126.488 86.315  1.00 102.10 ? 297 ASP R CG  1 
ATOM 2025 O OD1 . ASP A 1 353 ? 111.930 127.352 86.174  1.00 102.42 ? 297 ASP R OD1 1 
ATOM 2026 O OD2 . ASP A 1 353 ? 112.702 125.519 87.092  1.00 99.89  ? 297 ASP R OD2 1 
ATOM 2027 N N   . ALA A 1 354 ? 116.123 124.266 86.049  1.00 102.21 ? 298 ALA R N   1 
ATOM 2028 C CA  . ALA A 1 354 ? 116.369 122.900 86.507  1.00 102.37 ? 298 ALA R CA  1 
ATOM 2029 C C   . ALA A 1 354 ? 117.347 122.880 87.679  1.00 102.37 ? 298 ALA R C   1 
ATOM 2030 O O   . ALA A 1 354 ? 117.118 122.200 88.689  1.00 100.54 ? 298 ALA R O   1 
ATOM 2031 C CB  . ALA A 1 354 ? 116.891 122.047 85.351  1.00 100.33 ? 298 ALA R CB  1 
ATOM 2032 N N   . THR A 1 355 ? 118.438 123.641 87.570  1.00 96.60  ? 299 THR R N   1 
ATOM 2033 C CA  . THR A 1 355 ? 119.438 123.676 88.628  1.00 93.30  ? 299 THR R CA  1 
ATOM 2034 C C   . THR A 1 355 ? 118.915 124.368 89.877  1.00 94.24  ? 299 THR R C   1 
ATOM 2035 O O   . THR A 1 355 ? 119.275 123.977 90.990  1.00 95.17  ? 299 THR R O   1 
ATOM 2036 C CB  . THR A 1 355 ? 120.701 124.373 88.131  1.00 94.10  ? 299 THR R CB  1 
ATOM 2037 O OG1 . THR A 1 355 ? 120.339 125.566 87.426  1.00 100.71 ? 299 THR R OG1 1 
ATOM 2038 C CG2 . THR A 1 355 ? 121.472 123.458 87.197  1.00 93.17  ? 299 THR R CG2 1 
ATOM 2039 N N   . GLU A 1 356 ? 118.079 125.397 89.720  1.00 96.43  ? 300 GLU R N   1 
ATOM 2040 C CA  . GLU A 1 356 ? 117.465 126.026 90.883  1.00 97.93  ? 300 GLU R CA  1 
ATOM 2041 C C   . GLU A 1 356 ? 116.578 125.039 91.629  1.00 97.56  ? 300 GLU R C   1 
ATOM 2042 O O   . GLU A 1 356 ? 116.620 124.960 92.865  1.00 98.01  ? 300 GLU R O   1 
ATOM 2043 C CB  . GLU A 1 356 ? 116.665 127.255 90.448  1.00 97.88  ? 300 GLU R CB  1 
ATOM 2044 C CG  . GLU A 1 356 ? 115.508 127.609 91.365  1.00 98.19  ? 300 GLU R CG  1 
ATOM 2045 C CD  . GLU A 1 356 ? 114.654 128.735 90.815  1.00 98.45  ? 300 GLU R CD  1 
ATOM 2046 O OE1 . GLU A 1 356 ? 115.145 129.486 89.947  1.00 97.65  ? 300 GLU R OE1 1 
ATOM 2047 O OE2 . GLU A 1 356 ? 113.491 128.866 91.250  1.00 99.14  ? 300 GLU R OE2 1 
ATOM 2048 N N   . ILE A 1 357 ? 115.778 124.264 90.892  1.00 97.09  ? 301 ILE R N   1 
ATOM 2049 C CA  . ILE A 1 357 ? 114.940 123.251 91.525  1.00 98.58  ? 301 ILE R CA  1 
ATOM 2050 C C   . ILE A 1 357 ? 115.803 122.218 92.240  1.00 100.22 ? 301 ILE R C   1 
ATOM 2051 O O   . ILE A 1 357 ? 115.511 121.823 93.375  1.00 98.11  ? 301 ILE R O   1 
ATOM 2052 C CB  . ILE A 1 357 ? 114.011 122.597 90.486  1.00 97.88  ? 301 ILE R CB  1 
ATOM 2053 C CG1 . ILE A 1 357 ? 112.790 123.481 90.237  1.00 96.50  ? 301 ILE R CG1 1 
ATOM 2054 C CG2 . ILE A 1 357 ? 113.577 121.211 90.939  1.00 97.63  ? 301 ILE R CG2 1 
ATOM 2055 C CD1 . ILE A 1 357 ? 111.759 122.840 89.350  1.00 99.24  ? 301 ILE R CD1 1 
ATOM 2056 N N   . LEU A 1 358 ? 116.882 121.770 91.592  1.00 99.05  ? 302 LEU R N   1 
ATOM 2057 C CA  . LEU A 1 358 ? 117.762 120.789 92.222  1.00 97.30  ? 302 LEU R CA  1 
ATOM 2058 C C   . LEU A 1 358 ? 118.399 121.341 93.492  1.00 94.96  ? 302 LEU R C   1 
ATOM 2059 O O   . LEU A 1 358 ? 118.476 120.644 94.510  1.00 95.19  ? 302 LEU R O   1 
ATOM 2060 C CB  . LEU A 1 358 ? 118.842 120.339 91.238  1.00 94.35  ? 302 LEU R CB  1 
ATOM 2061 C CG  . LEU A 1 358 ? 119.833 119.304 91.777  1.00 89.24  ? 302 LEU R CG  1 
ATOM 2062 C CD1 . LEU A 1 358 ? 119.104 118.057 92.248  1.00 93.84  ? 302 LEU R CD1 1 
ATOM 2063 C CD2 . LEU A 1 358 ? 120.873 118.954 90.727  1.00 89.77  ? 302 LEU R CD2 1 
ATOM 2064 N N   . GLY A 1 359 ? 118.857 122.594 93.455  1.00 93.13  ? 303 GLY R N   1 
ATOM 2065 C CA  . GLY A 1 359 ? 119.534 123.180 94.596  1.00 93.66  ? 303 GLY R CA  1 
ATOM 2066 C C   . GLY A 1 359 ? 118.619 123.549 95.742  1.00 98.49  ? 303 GLY R C   1 
ATOM 2067 O O   . GLY A 1 359 ? 119.080 123.631 96.885  1.00 99.96  ? 303 GLY R O   1 
ATOM 2068 N N   . ILE A 1 360 ? 117.333 123.777 95.464  1.00 97.98  ? 304 ILE R N   1 
ATOM 2069 C CA  . ILE A 1 360 ? 116.387 124.077 96.532  1.00 93.77  ? 304 ILE R CA  1 
ATOM 2070 C C   . ILE A 1 360 ? 116.277 122.919 97.519  1.00 96.31  ? 304 ILE R C   1 
ATOM 2071 O O   . ILE A 1 360 ? 115.942 123.130 98.690  1.00 97.70  ? 304 ILE R O   1 
ATOM 2072 C CB  . ILE A 1 360 ? 115.026 124.459 95.906  1.00 95.37  ? 304 ILE R CB  1 
ATOM 2073 C CG1 . ILE A 1 360 ? 115.030 125.935 95.512  1.00 98.07  ? 304 ILE R CG1 1 
ATOM 2074 C CG2 . ILE A 1 360 ? 113.869 124.193 96.847  1.00 96.42  ? 304 ILE R CG2 1 
ATOM 2075 C CD1 . ILE A 1 360 ? 113.823 126.351 94.718  1.00 99.32  ? 304 ILE R CD1 1 
ATOM 2076 N N   . LEU A 1 361 ? 116.624 121.703 97.092  1.00 100.53 ? 305 LEU R N   1 
ATOM 2077 C CA  . LEU A 1 361 ? 116.511 120.502 97.917  1.00 101.04 ? 305 LEU R CA  1 
ATOM 2078 C C   . LEU A 1 361 ? 117.383 120.543 99.168  1.00 98.72  ? 305 LEU R C   1 
ATOM 2079 O O   . LEU A 1 361 ? 117.365 119.598 99.965  1.00 99.15  ? 305 LEU R O   1 
ATOM 2080 C CB  . LEU A 1 361 ? 116.876 119.263 97.095  1.00 99.11  ? 305 LEU R CB  1 
ATOM 2081 C CG  . LEU A 1 361 ? 115.939 118.842 95.965  1.00 97.20  ? 305 LEU R CG  1 
ATOM 2082 C CD1 . LEU A 1 361 ? 116.538 117.679 95.197  1.00 97.48  ? 305 LEU R CD1 1 
ATOM 2083 C CD2 . LEU A 1 361 ? 114.581 118.464 96.522  1.00 96.37  ? 305 LEU R CD2 1 
ATOM 2084 N N   . HIS A 1 362 ? 118.165 121.612 99.343  1.00 90.08  ? 306 HIS R N   1 
ATOM 2085 C CA  . HIS A 1 362 ? 118.993 121.724 100.539 1.00 91.90  ? 306 HIS R CA  1 
ATOM 2086 C C   . HIS A 1 362 ? 118.134 121.795 101.795 1.00 91.09  ? 306 HIS R C   1 
ATOM 2087 O O   . HIS A 1 362 ? 118.449 121.159 102.808 1.00 91.88  ? 306 HIS R O   1 
ATOM 2088 C CB  . HIS A 1 362 ? 119.919 122.939 100.429 1.00 90.94  ? 306 HIS R CB  1 
ATOM 2089 C CG  . HIS A 1 362 ? 119.257 124.245 100.744 1.00 93.05  ? 306 HIS R CG  1 
ATOM 2090 N ND1 . HIS A 1 362 ? 119.220 124.774 102.016 1.00 93.20  ? 306 HIS R ND1 1 
ATOM 2091 C CD2 . HIS A 1 362 ? 118.611 125.131 99.949  1.00 92.14  ? 306 HIS R CD2 1 
ATOM 2092 C CE1 . HIS A 1 362 ? 118.578 125.929 101.992 1.00 89.77  ? 306 HIS R CE1 1 
ATOM 2093 N NE2 . HIS A 1 362 ? 118.198 126.168 100.750 1.00 91.47  ? 306 HIS R NE2 1 
ATOM 2094 N N   . SER A 1 363 ? 117.033 122.548 101.742 1.00 92.18  ? 307 SER R N   1 
ATOM 2095 C CA  . SER A 1 363 ? 116.143 122.636 102.894 1.00 93.14  ? 307 SER R CA  1 
ATOM 2096 C C   . SER A 1 363 ? 115.460 121.305 103.177 1.00 96.30  ? 307 SER R C   1 
ATOM 2097 O O   . SER A 1 363 ? 115.150 121.003 104.334 1.00 94.18  ? 307 SER R O   1 
ATOM 2098 C CB  . SER A 1 363 ? 115.101 123.732 102.669 1.00 92.01  ? 307 SER R CB  1 
ATOM 2099 O OG  . SER A 1 363 ? 114.167 123.351 101.674 1.00 93.04  ? 307 SER R OG  1 
ATOM 2100 N N   . CYS A 1 364 ? 115.218 120.502 102.140 1.00 100.50 ? 308 CYS R N   1 
ATOM 2101 C CA  . CYS A 1 364 ? 114.604 119.195 102.338 1.00 100.16 ? 308 CYS R CA  1 
ATOM 2102 C C   . CYS A 1 364 ? 115.586 118.196 102.934 1.00 99.47  ? 308 CYS R C   1 
ATOM 2103 O O   . CYS A 1 364 ? 115.215 117.399 103.803 1.00 103.01 ? 308 CYS R O   1 
ATOM 2104 C CB  . CYS A 1 364 ? 114.058 118.668 101.012 1.00 98.72  ? 308 CYS R CB  1 
ATOM 2105 S SG  . CYS A 1 364 ? 112.415 119.277 100.593 1.00 111.81 ? 308 CYS R SG  1 
ATOM 2106 N N   . LEU A 1 365 ? 116.838 118.222 102.483 1.00 85.57  ? 309 LEU R N   1 
ATOM 2107 C CA  . LEU A 1 365 ? 117.815 117.226 102.901 1.00 86.41  ? 309 LEU R CA  1 
ATOM 2108 C C   . LEU A 1 365 ? 118.595 117.620 104.149 1.00 85.89  ? 309 LEU R C   1 
ATOM 2109 O O   . LEU A 1 365 ? 119.307 116.774 104.700 1.00 87.90  ? 309 LEU R O   1 
ATOM 2110 C CB  . LEU A 1 365 ? 118.793 116.941 101.757 1.00 90.34  ? 309 LEU R CB  1 
ATOM 2111 C CG  . LEU A 1 365 ? 118.457 115.735 100.876 1.00 89.40  ? 309 LEU R CG  1 
ATOM 2112 C CD1 . LEU A 1 365 ? 119.539 115.509 99.837  1.00 89.66  ? 309 LEU R CD1 1 
ATOM 2113 C CD2 . LEU A 1 365 ? 118.266 114.489 101.725 1.00 86.92  ? 309 LEU R CD2 1 
ATOM 2114 N N   . ASN A 1 366 ? 118.485 118.866 104.609 1.00 82.05  ? 310 ASN R N   1 
ATOM 2115 C CA  . ASN A 1 366 ? 119.203 119.265 105.819 1.00 83.77  ? 310 ASN R CA  1 
ATOM 2116 C C   . ASN A 1 366 ? 118.799 118.471 107.057 1.00 81.94  ? 310 ASN R C   1 
ATOM 2117 O O   . ASN A 1 366 ? 119.698 118.059 107.811 1.00 83.41  ? 310 ASN R O   1 
ATOM 2118 C CB  . ASN A 1 366 ? 119.028 120.770 106.042 1.00 81.99  ? 310 ASN R CB  1 
ATOM 2119 C CG  . ASN A 1 366 ? 120.125 121.586 105.391 1.00 83.79  ? 310 ASN R CG  1 
ATOM 2120 O OD1 . ASN A 1 366 ? 120.852 121.092 104.530 1.00 84.67  ? 310 ASN R OD1 1 
ATOM 2121 N ND2 . ASN A 1 366 ? 120.243 122.845 105.789 1.00 82.20  ? 310 ASN R ND2 1 
ATOM 2122 N N   . PRO A 1 367 ? 117.500 118.235 107.352 1.00 89.81  ? 311 PRO R N   1 
ATOM 2123 C CA  . PRO A 1 367 ? 117.162 117.473 108.565 1.00 90.10  ? 311 PRO R CA  1 
ATOM 2124 C C   . PRO A 1 367 ? 117.772 116.080 108.596 1.00 89.01  ? 311 PRO R C   1 
ATOM 2125 O O   . PRO A 1 367 ? 118.550 115.766 109.501 1.00 87.34  ? 311 PRO R O   1 
ATOM 2126 C CB  . PRO A 1 367 ? 115.630 117.404 108.525 1.00 88.49  ? 311 PRO R CB  1 
ATOM 2127 C CG  . PRO A 1 367 ? 115.218 118.556 107.705 1.00 91.78  ? 311 PRO R CG  1 
ATOM 2128 C CD  . PRO A 1 367 ? 116.290 118.743 106.680 1.00 91.47  ? 311 PRO R CD  1 
ATOM 2129 N N   . LEU A 1 368 ? 117.455 115.253 107.597 1.00 86.36  ? 312 LEU R N   1 
ATOM 2130 C CA  . LEU A 1 368 ? 117.904 113.864 107.600 1.00 85.29  ? 312 LEU R CA  1 
ATOM 2131 C C   . LEU A 1 368 ? 119.421 113.741 107.619 1.00 89.40  ? 312 LEU R C   1 
ATOM 2132 O O   . LEU A 1 368 ? 119.942 112.691 108.010 1.00 94.13  ? 312 LEU R O   1 
ATOM 2133 C CB  . LEU A 1 368 ? 117.346 113.129 106.380 1.00 85.54  ? 312 LEU R CB  1 
ATOM 2134 C CG  . LEU A 1 368 ? 115.900 113.416 105.972 1.00 87.05  ? 312 LEU R CG  1 
ATOM 2135 C CD1 . LEU A 1 368 ? 115.503 112.537 104.799 1.00 89.65  ? 312 LEU R CD1 1 
ATOM 2136 C CD2 . LEU A 1 368 ? 114.950 113.204 107.139 1.00 87.69  ? 312 LEU R CD2 1 
ATOM 2137 N N   . ILE A 1 369 ? 120.136 114.781 107.203 1.00 83.34  ? 313 ILE R N   1 
ATOM 2138 C CA  . ILE A 1 369 ? 121.591 114.726 107.114 1.00 80.05  ? 313 ILE R CA  1 
ATOM 2139 C C   . ILE A 1 369 ? 122.255 115.254 108.380 1.00 80.20  ? 313 ILE R C   1 
ATOM 2140 O O   . ILE A 1 369 ? 123.265 114.707 108.830 1.00 79.20  ? 313 ILE R O   1 
ATOM 2141 C CB  . ILE A 1 369 ? 122.047 115.496 105.860 1.00 76.55  ? 313 ILE R CB  1 
ATOM 2142 C CG1 . ILE A 1 369 ? 121.981 114.581 104.641 1.00 80.18  ? 313 ILE R CG1 1 
ATOM 2143 C CG2 . ILE A 1 369 ? 123.443 116.061 106.038 1.00 76.21  ? 313 ILE R CG2 1 
ATOM 2144 C CD1 . ILE A 1 369 ? 121.843 115.318 103.346 1.00 79.59  ? 313 ILE R CD1 1 
ATOM 2145 N N   . TYR A 1 370 ? 121.705 116.306 108.984 1.00 78.13  ? 314 TYR R N   1 
ATOM 2146 C CA  . TYR A 1 370 ? 122.332 116.941 110.137 1.00 77.67  ? 314 TYR R CA  1 
ATOM 2147 C C   . TYR A 1 370 ? 121.752 116.478 111.470 1.00 77.83  ? 314 TYR R C   1 
ATOM 2148 O O   . TYR A 1 370 ? 122.509 116.173 112.395 1.00 74.14  ? 314 TYR R O   1 
ATOM 2149 C CB  . TYR A 1 370 ? 122.219 118.466 110.020 1.00 75.70  ? 314 TYR R CB  1 
ATOM 2150 C CG  . TYR A 1 370 ? 123.252 119.079 109.100 1.00 76.34  ? 314 TYR R CG  1 
ATOM 2151 C CD1 . TYR A 1 370 ? 124.511 119.421 109.570 1.00 72.30  ? 314 TYR R CD1 1 
ATOM 2152 C CD2 . TYR A 1 370 ? 122.969 119.307 107.761 1.00 76.60  ? 314 TYR R CD2 1 
ATOM 2153 C CE1 . TYR A 1 370 ? 125.456 119.978 108.734 1.00 73.39  ? 314 TYR R CE1 1 
ATOM 2154 C CE2 . TYR A 1 370 ? 123.908 119.863 106.918 1.00 72.51  ? 314 TYR R CE2 1 
ATOM 2155 C CZ  . TYR A 1 370 ? 125.150 120.196 107.409 1.00 73.37  ? 314 TYR R CZ  1 
ATOM 2156 O OH  . TYR A 1 370 ? 126.089 120.750 106.571 1.00 72.43  ? 314 TYR R OH  1 
ATOM 2157 N N   . ALA A 1 371 ? 120.426 116.420 111.595 1.00 88.34  ? 315 ALA R N   1 
ATOM 2158 C CA  . ALA A 1 371 ? 119.802 116.148 112.886 1.00 89.74  ? 315 ALA R CA  1 
ATOM 2159 C C   . ALA A 1 371 ? 119.522 114.663 113.093 1.00 90.34  ? 315 ALA R C   1 
ATOM 2160 O O   . ALA A 1 371 ? 120.030 114.055 114.040 1.00 91.66  ? 315 ALA R O   1 
ATOM 2161 C CB  . ALA A 1 371 ? 118.503 116.953 113.015 1.00 87.92  ? 315 ALA R CB  1 
ATOM 2162 N N   . PHE A 1 372 ? 118.723 114.067 112.211 1.00 91.25  ? 316 PHE R N   1 
ATOM 2163 C CA  . PHE A 1 372 ? 118.226 112.717 112.438 1.00 92.87  ? 316 PHE R CA  1 
ATOM 2164 C C   . PHE A 1 372 ? 119.270 111.641 112.173 1.00 92.88  ? 316 PHE R C   1 
ATOM 2165 O O   . PHE A 1 372 ? 119.010 110.468 112.461 1.00 95.08  ? 316 PHE R O   1 
ATOM 2166 C CB  . PHE A 1 372 ? 116.988 112.469 111.573 1.00 91.44  ? 316 PHE R CB  1 
ATOM 2167 C CG  . PHE A 1 372 ? 115.800 113.301 111.970 1.00 92.37  ? 316 PHE R CG  1 
ATOM 2168 C CD1 . PHE A 1 372 ? 115.293 113.238 113.257 1.00 94.30  ? 316 PHE R CD1 1 
ATOM 2169 C CD2 . PHE A 1 372 ? 115.199 114.154 111.060 1.00 93.38  ? 316 PHE R CD2 1 
ATOM 2170 C CE1 . PHE A 1 372 ? 114.205 114.006 113.625 1.00 95.09  ? 316 PHE R CE1 1 
ATOM 2171 C CE2 . PHE A 1 372 ? 114.111 114.923 111.424 1.00 91.22  ? 316 PHE R CE2 1 
ATOM 2172 C CZ  . PHE A 1 372 ? 113.614 114.848 112.708 1.00 91.22  ? 316 PHE R CZ  1 
ATOM 2173 N N   . ILE A 1 373 ? 120.439 112.004 111.638 1.00 87.92  ? 317 ILE R N   1 
ATOM 2174 C CA  . ILE A 1 373 ? 121.491 111.018 111.394 1.00 91.22  ? 317 ILE R CA  1 
ATOM 2175 C C   . ILE A 1 373 ? 122.205 110.601 112.669 1.00 93.43  ? 317 ILE R C   1 
ATOM 2176 O O   . ILE A 1 373 ? 122.965 109.624 112.652 1.00 92.58  ? 317 ILE R O   1 
ATOM 2177 C CB  . ILE A 1 373 ? 122.505 111.564 110.371 1.00 87.95  ? 317 ILE R CB  1 
ATOM 2178 C CG1 . ILE A 1 373 ? 123.146 110.419 109.587 1.00 86.87  ? 317 ILE R CG1 1 
ATOM 2179 C CG2 . ILE A 1 373 ? 123.571 112.398 111.066 1.00 87.20  ? 317 ILE R CG2 1 
ATOM 2180 C CD1 . ILE A 1 373 ? 124.099 110.882 108.513 1.00 87.34  ? 317 ILE R CD1 1 
ATOM 2181 N N   . GLY A 1 374 ? 121.979 111.308 113.776 1.00 100.36 ? 318 GLY R N   1 
ATOM 2182 C CA  . GLY A 1 374 ? 122.559 110.951 115.050 1.00 99.06  ? 318 GLY R CA  1 
ATOM 2183 C C   . GLY A 1 374 ? 121.558 110.257 115.954 1.00 97.99  ? 318 GLY R C   1 
ATOM 2184 O O   . GLY A 1 374 ? 120.348 110.425 115.821 1.00 98.77  ? 318 GLY R O   1 
ATOM 2185 N N   . GLN A 1 375 ? 122.085 109.463 116.889 1.00 105.00 ? 319 GLN R N   1 
ATOM 2186 C CA  . GLN A 1 375 ? 121.216 108.699 117.778 1.00 106.72 ? 319 GLN R CA  1 
ATOM 2187 C C   . GLN A 1 375 ? 120.529 109.591 118.804 1.00 110.39 ? 319 GLN R C   1 
ATOM 2188 O O   . GLN A 1 375 ? 119.439 109.253 119.283 1.00 110.92 ? 319 GLN R O   1 
ATOM 2189 C CB  . GLN A 1 375 ? 122.017 107.602 118.479 1.00 106.82 ? 319 GLN R CB  1 
ATOM 2190 C CG  . GLN A 1 375 ? 121.161 106.524 119.127 1.00 110.02 ? 319 GLN R CG  1 
ATOM 2191 C CD  . GLN A 1 375 ? 121.637 105.123 118.796 1.00 109.84 ? 319 GLN R CD  1 
ATOM 2192 O OE1 . GLN A 1 375 ? 122.527 104.937 117.966 1.00 110.92 ? 319 GLN R OE1 1 
ATOM 2193 N NE2 . GLN A 1 375 ? 121.045 104.127 119.445 1.00 107.22 ? 319 GLN R NE2 1 
ATOM 2194 N N   . LYS A 1 376 ? 121.139 110.728 119.145 1.00 106.12 ? 320 LYS R N   1 
ATOM 2195 C CA  . LYS A 1 376 ? 120.559 111.603 120.159 1.00 105.01 ? 320 LYS R CA  1 
ATOM 2196 C C   . LYS A 1 376 ? 119.203 112.139 119.721 1.00 102.11 ? 320 LYS R C   1 
ATOM 2197 O O   . LYS A 1 376 ? 118.248 112.145 120.505 1.00 99.30  ? 320 LYS R O   1 
ATOM 2198 C CB  . LYS A 1 376 ? 121.516 112.754 120.467 1.00 104.94 ? 320 LYS R CB  1 
ATOM 2199 N N   . PHE A 1 377 ? 119.092 112.576 118.466 1.00 103.31 ? 321 PHE R N   1 
ATOM 2200 C CA  . PHE A 1 377 ? 117.846 113.183 118.010 1.00 104.07 ? 321 PHE R CA  1 
ATOM 2201 C C   . PHE A 1 377 ? 116.753 112.139 117.817 1.00 103.16 ? 321 PHE R C   1 
ATOM 2202 O O   . PHE A 1 377 ? 115.581 112.401 118.110 1.00 104.47 ? 321 PHE R O   1 
ATOM 2203 C CB  . PHE A 1 377 ? 118.089 113.964 116.722 1.00 101.74 ? 321 PHE R CB  1 
ATOM 2204 C CG  . PHE A 1 377 ? 118.335 115.423 116.949 1.00 101.35 ? 321 PHE R CG  1 
ATOM 2205 C CD1 . PHE A 1 377 ? 117.283 116.318 116.977 1.00 101.46 ? 321 PHE R CD1 1 
ATOM 2206 C CD2 . PHE A 1 377 ? 119.618 115.895 117.163 1.00 102.41 ? 321 PHE R CD2 1 
ATOM 2207 C CE1 . PHE A 1 377 ? 117.506 117.660 117.196 1.00 104.52 ? 321 PHE R CE1 1 
ATOM 2208 C CE2 . PHE A 1 377 ? 119.847 117.236 117.385 1.00 101.72 ? 321 PHE R CE2 1 
ATOM 2209 C CZ  . PHE A 1 377 ? 118.790 118.120 117.400 1.00 103.46 ? 321 PHE R CZ  1 
ATOM 2210 N N   . ARG A 1 378 ? 117.114 110.952 117.328 1.00 104.82 ? 322 ARG R N   1 
ATOM 2211 C CA  . ARG A 1 378 ? 116.137 109.872 117.233 1.00 105.06 ? 322 ARG R CA  1 
ATOM 2212 C C   . ARG A 1 378 ? 115.635 109.467 118.614 1.00 105.12 ? 322 ARG R C   1 
ATOM 2213 O O   . ARG A 1 378 ? 114.434 109.238 118.807 1.00 102.62 ? 322 ARG R O   1 
ATOM 2214 C CB  . ARG A 1 378 ? 116.748 108.676 116.507 1.00 104.92 ? 322 ARG R CB  1 
ATOM 2215 C CG  . ARG A 1 378 ? 116.864 108.863 115.005 1.00 105.65 ? 322 ARG R CG  1 
ATOM 2216 C CD  . ARG A 1 378 ? 117.523 107.665 114.351 1.00 105.09 ? 322 ARG R CD  1 
ATOM 2217 N NE  . ARG A 1 378 ? 118.977 107.748 114.403 1.00 103.92 ? 322 ARG R NE  1 
ATOM 2218 C CZ  . ARG A 1 378 ? 119.757 106.843 114.975 1.00 106.53 ? 322 ARG R CZ  1 
ATOM 2219 N NH1 . ARG A 1 378 ? 119.254 105.773 115.569 1.00 107.44 ? 322 ARG R NH1 1 
ATOM 2220 N NH2 . ARG A 1 378 ? 121.075 107.014 114.950 1.00 105.60 ? 322 ARG R NH2 1 
ATOM 2221 N N   . HIS A 1 379 ? 116.544 109.380 119.589 1.00 114.52 ? 323 HIS R N   1 
ATOM 2222 C CA  . HIS A 1 379 ? 116.142 109.070 120.956 1.00 118.50 ? 323 HIS R CA  1 
ATOM 2223 C C   . HIS A 1 379 ? 115.229 110.152 121.518 1.00 116.09 ? 323 HIS R C   1 
ATOM 2224 O O   . HIS A 1 379 ? 114.234 109.852 122.190 1.00 111.99 ? 323 HIS R O   1 
ATOM 2225 C CB  . HIS A 1 379 ? 117.383 108.898 121.833 1.00 116.45 ? 323 HIS R CB  1 
ATOM 2226 C CG  . HIS A 1 379 ? 117.096 108.335 123.189 1.00 115.75 ? 323 HIS R CG  1 
ATOM 2227 N ND1 . HIS A 1 379 ? 116.685 107.034 123.384 1.00 116.62 ? 323 HIS R ND1 1 
ATOM 2228 C CD2 . HIS A 1 379 ? 117.170 108.895 124.420 1.00 114.03 ? 323 HIS R CD2 1 
ATOM 2229 C CE1 . HIS A 1 379 ? 116.514 106.818 124.676 1.00 116.62 ? 323 HIS R CE1 1 
ATOM 2230 N NE2 . HIS A 1 379 ? 116.801 107.930 125.327 1.00 116.01 ? 323 HIS R NE2 1 
ATOM 2231 N N   . GLY A 1 380 ? 115.549 111.419 121.247 1.00 113.06 ? 324 GLY R N   1 
ATOM 2232 C CA  . GLY A 1 380 ? 114.695 112.503 121.704 1.00 111.77 ? 324 GLY R CA  1 
ATOM 2233 C C   . GLY A 1 380 ? 113.311 112.455 121.089 1.00 110.02 ? 324 GLY R C   1 
ATOM 2234 O O   . GLY A 1 380 ? 112.311 112.666 121.776 1.00 110.36 ? 324 GLY R O   1 
ATOM 2235 N N   . LEU A 1 381 ? 113.233 112.175 119.786 1.00 110.72 ? 325 LEU R N   1 
ATOM 2236 C CA  . LEU A 1 381 ? 111.933 112.054 119.131 1.00 113.04 ? 325 LEU R CA  1 
ATOM 2237 C C   . LEU A 1 381 ? 111.129 110.893 119.706 1.00 115.24 ? 325 LEU R C   1 
ATOM 2238 O O   . LEU A 1 381 ? 109.923 111.024 119.954 1.00 110.87 ? 325 LEU R O   1 
ATOM 2239 C CB  . LEU A 1 381 ? 112.119 111.886 117.623 1.00 112.50 ? 325 LEU R CB  1 
ATOM 2240 C CG  . LEU A 1 381 ? 110.847 111.798 116.776 1.00 108.11 ? 325 LEU R CG  1 
ATOM 2241 C CD1 . LEU A 1 381 ? 110.187 113.159 116.641 1.00 108.26 ? 325 LEU R CD1 1 
ATOM 2242 C CD2 . LEU A 1 381 ? 111.158 111.213 115.408 1.00 106.64 ? 325 LEU R CD2 1 
ATOM 2243 N N   . LEU A 1 382 ? 111.782 109.749 119.930 1.00 116.08 ? 326 LEU R N   1 
ATOM 2244 C CA  . LEU A 1 382 ? 111.086 108.608 120.516 1.00 112.55 ? 326 LEU R CA  1 
ATOM 2245 C C   . LEU A 1 382 ? 110.572 108.936 121.912 1.00 115.31 ? 326 LEU R C   1 
ATOM 2246 O O   . LEU A 1 382 ? 109.455 108.552 122.277 1.00 115.11 ? 326 LEU R O   1 
ATOM 2247 C CB  . LEU A 1 382 ? 112.010 107.391 120.553 1.00 110.15 ? 326 LEU R CB  1 
ATOM 2248 N N   . LYS A 1 383 ? 111.377 109.644 122.708 1.00 119.22 ? 327 LYS R N   1 
ATOM 2249 C CA  . LYS A 1 383 ? 110.930 110.069 124.032 1.00 116.76 ? 327 LYS R CA  1 
ATOM 2250 C C   . LYS A 1 383 ? 109.749 111.028 123.935 1.00 114.43 ? 327 LYS R C   1 
ATOM 2251 O O   . LYS A 1 383 ? 108.806 110.948 124.731 1.00 113.45 ? 327 LYS R O   1 
ATOM 2252 C CB  . LYS A 1 383 ? 112.089 110.716 124.789 1.00 114.87 ? 327 LYS R CB  1 
ATOM 2253 C CG  . LYS A 1 383 ? 111.762 111.113 126.218 1.00 117.29 ? 327 LYS R CG  1 
ATOM 2254 C CD  . LYS A 1 383 ? 112.885 111.936 126.831 1.00 117.25 ? 327 LYS R CD  1 
ATOM 2255 C CE  . LYS A 1 383 ? 114.220 111.212 126.747 1.00 116.32 ? 327 LYS R CE  1 
ATOM 2256 N NZ  . LYS A 1 383 ? 114.137 109.814 127.257 1.00 116.32 ? 327 LYS R NZ  1 
ATOM 2257 N N   . ILE A 1 384 ? 109.788 111.948 122.968 1.00 114.94 ? 328 ILE R N   1 
ATOM 2258 C CA  . ILE A 1 384 ? 108.700 112.906 122.794 1.00 117.74 ? 328 ILE R CA  1 
ATOM 2259 C C   . ILE A 1 384 ? 107.417 112.197 122.378 1.00 117.40 ? 328 ILE R C   1 
ATOM 2260 O O   . ILE A 1 384 ? 106.314 112.635 122.732 1.00 115.71 ? 328 ILE R O   1 
ATOM 2261 C CB  . ILE A 1 384 ? 109.111 113.992 121.780 1.00 117.31 ? 328 ILE R CB  1 
ATOM 2262 C CG1 . ILE A 1 384 ? 110.226 114.866 122.358 1.00 116.50 ? 328 ILE R CG1 1 
ATOM 2263 C CG2 . ILE A 1 384 ? 107.924 114.859 121.387 1.00 114.30 ? 328 ILE R CG2 1 
ATOM 2264 C CD1 . ILE A 1 384 ? 110.023 115.244 123.804 1.00 115.71 ? 328 ILE R CD1 1 
ATOM 2265 N N   . LEU A 1 385 ? 107.532 111.083 121.647 1.00 116.13 ? 329 LEU R N   1 
ATOM 2266 C CA  . LEU A 1 385 ? 106.348 110.363 121.189 1.00 116.53 ? 329 LEU R CA  1 
ATOM 2267 C C   . LEU A 1 385 ? 105.462 109.895 122.339 1.00 118.01 ? 329 LEU R C   1 
ATOM 2268 O O   . LEU A 1 385 ? 104.271 109.648 122.125 1.00 116.60 ? 329 LEU R O   1 
ATOM 2269 C CB  . LEU A 1 385 ? 106.759 109.161 120.336 1.00 115.72 ? 329 LEU R CB  1 
ATOM 2270 C CG  . LEU A 1 385 ? 107.247 109.457 118.917 1.00 114.57 ? 329 LEU R CG  1 
ATOM 2271 C CD1 . LEU A 1 385 ? 107.696 108.178 118.228 1.00 113.24 ? 329 LEU R CD1 1 
ATOM 2272 C CD2 . LEU A 1 385 ? 106.166 110.157 118.109 1.00 115.72 ? 329 LEU R CD2 1 
ATOM 2273 N N   . ALA A 1 386 ? 106.010 109.769 123.544 1.00 123.83 ? 330 ALA R N   1 
ATOM 2274 C CA  . ALA A 1 386 ? 105.222 109.378 124.708 1.00 123.14 ? 330 ALA R CA  1 
ATOM 2275 C C   . ALA A 1 386 ? 104.418 110.560 125.244 1.00 121.85 ? 330 ALA R C   1 
ATOM 2276 O O   . ALA A 1 386 ? 103.214 110.663 125.010 1.00 120.79 ? 330 ALA R O   1 
ATOM 2277 C CB  . ALA A 1 386 ? 106.123 108.813 125.794 1.00 119.89 ? 330 ALA R CB  1 
ATOM 2278 N N   . THR B 2 16  ? 120.206 148.433 145.050 1.00 95.40  ? 4   THR A N   1 
ATOM 2279 C CA  . THR B 2 16  ? 121.300 149.023 144.292 1.00 94.87  ? 4   THR A CA  1 
ATOM 2280 C C   . THR B 2 16  ? 121.223 150.542 144.454 1.00 94.27  ? 4   THR A C   1 
ATOM 2281 O O   . THR B 2 16  ? 122.174 151.269 144.170 1.00 92.47  ? 4   THR A O   1 
ATOM 2282 C CB  . THR B 2 16  ? 121.235 148.606 142.802 1.00 97.61  ? 4   THR A CB  1 
ATOM 2283 O OG1 . THR B 2 16  ? 121.372 147.184 142.706 1.00 96.01  ? 4   THR A OG1 1 
ATOM 2284 C CG2 . THR B 2 16  ? 122.355 149.245 141.993 1.00 97.78  ? 4   THR A CG2 1 
ATOM 2285 N N   . LEU B 2 17  ? 120.078 151.010 144.955 1.00 90.61  ? 5   LEU A N   1 
ATOM 2286 C CA  . LEU B 2 17  ? 119.874 152.444 145.129 1.00 90.89  ? 5   LEU A CA  1 
ATOM 2287 C C   . LEU B 2 17  ? 120.865 153.033 146.127 1.00 89.51  ? 5   LEU A C   1 
ATOM 2288 O O   . LEU B 2 17  ? 121.392 154.131 145.916 1.00 91.60  ? 5   LEU A O   1 
ATOM 2289 C CB  . LEU B 2 17  ? 118.437 152.715 145.573 1.00 90.14  ? 5   LEU A CB  1 
ATOM 2290 C CG  . LEU B 2 17  ? 117.342 152.416 144.547 1.00 88.87  ? 5   LEU A CG  1 
ATOM 2291 C CD1 . LEU B 2 17  ? 115.984 152.865 145.062 1.00 88.18  ? 5   LEU A CD1 1 
ATOM 2292 C CD2 . LEU B 2 17  ? 117.657 153.079 143.215 1.00 87.74  ? 5   LEU A CD2 1 
ATOM 2293 N N   . SER B 2 18  ? 121.131 152.321 147.219 1.00 70.16  ? 6   SER A N   1 
ATOM 2294 C CA  . SER B 2 18  ? 122.025 152.823 148.250 1.00 70.02  ? 6   SER A CA  1 
ATOM 2295 C C   . SER B 2 18  ? 123.485 152.683 147.821 1.00 72.36  ? 6   SER A C   1 
ATOM 2296 O O   . SER B 2 18  ? 123.823 151.962 146.879 1.00 74.79  ? 6   SER A O   1 
ATOM 2297 C CB  . SER B 2 18  ? 121.787 152.089 149.567 1.00 69.82  ? 6   SER A CB  1 
ATOM 2298 O OG  . SER B 2 18  ? 122.509 152.698 150.621 1.00 66.56  ? 6   SER A OG  1 
ATOM 2299 N N   . ALA B 2 19  ? 124.361 153.399 148.531 1.00 61.48  ? 7   ALA A N   1 
ATOM 2300 C CA  . ALA B 2 19  ? 125.792 153.318 148.253 1.00 61.64  ? 7   ALA A CA  1 
ATOM 2301 C C   . ALA B 2 19  ? 126.373 151.993 148.733 1.00 65.49  ? 7   ALA A C   1 
ATOM 2302 O O   . ALA B 2 19  ? 127.157 151.349 148.023 1.00 63.60  ? 7   ALA A O   1 
ATOM 2303 C CB  . ALA B 2 19  ? 126.518 154.492 148.908 1.00 55.70  ? 7   ALA A CB  1 
ATOM 2304 N N   . GLU B 2 20  ? 126.001 151.573 149.945 1.00 60.31  ? 8   GLU A N   1 
ATOM 2305 C CA  . GLU B 2 20  ? 126.500 150.310 150.475 1.00 55.67  ? 8   GLU A CA  1 
ATOM 2306 C C   . GLU B 2 20  ? 126.033 149.137 149.627 1.00 53.98  ? 8   GLU A C   1 
ATOM 2307 O O   . GLU B 2 20  ? 126.780 148.174 149.421 1.00 63.78  ? 8   GLU A O   1 
ATOM 2308 C CB  . GLU B 2 20  ? 126.058 150.139 151.926 1.00 47.53  ? 8   GLU A CB  1 
ATOM 2309 C CG  . GLU B 2 20  ? 126.318 151.355 152.791 1.00 44.98  ? 8   GLU A CG  1 
ATOM 2310 C CD  . GLU B 2 20  ? 126.561 150.993 154.238 1.00 56.76  ? 8   GLU A CD  1 
ATOM 2311 O OE1 . GLU B 2 20  ? 126.883 149.819 154.512 1.00 62.03  ? 8   GLU A OE1 1 
ATOM 2312 O OE2 . GLU B 2 20  ? 126.430 151.884 155.102 1.00 61.30  ? 8   GLU A OE2 1 
ATOM 2313 N N   . GLU B 2 21  ? 124.801 149.198 149.121 1.00 57.18  ? 9   GLU A N   1 
ATOM 2314 C CA  . GLU B 2 21  ? 124.325 148.135 148.245 1.00 64.25  ? 9   GLU A CA  1 
ATOM 2315 C C   . GLU B 2 21  ? 125.063 148.141 146.911 1.00 65.72  ? 9   GLU A C   1 
ATOM 2316 O O   . GLU B 2 21  ? 125.310 147.074 146.338 1.00 77.37  ? 9   GLU A O   1 
ATOM 2317 C CB  . GLU B 2 21  ? 122.818 148.261 148.033 1.00 64.48  ? 9   GLU A CB  1 
ATOM 2318 C CG  . GLU B 2 21  ? 122.218 147.132 147.217 1.00 66.00  ? 9   GLU A CG  1 
ATOM 2319 C CD  . GLU B 2 21  ? 122.698 145.768 147.668 1.00 72.26  ? 9   GLU A CD  1 
ATOM 2320 O OE1 . GLU B 2 21  ? 122.503 145.428 148.854 1.00 71.75  ? 9   GLU A OE1 1 
ATOM 2321 O OE2 . GLU B 2 21  ? 123.271 145.034 146.836 1.00 67.56  ? 9   GLU A OE2 1 
ATOM 2322 N N   . ARG B 2 22  ? 125.436 149.321 146.409 1.00 53.57  ? 10  ARG A N   1 
ATOM 2323 C CA  . ARG B 2 22  ? 126.270 149.382 145.212 1.00 55.92  ? 10  ARG A CA  1 
ATOM 2324 C C   . ARG B 2 22  ? 127.623 148.728 145.452 1.00 58.48  ? 10  ARG A C   1 
ATOM 2325 O O   . ARG B 2 22  ? 128.126 147.984 144.600 1.00 62.46  ? 10  ARG A O   1 
ATOM 2326 C CB  . ARG B 2 22  ? 126.459 150.833 144.773 1.00 65.90  ? 10  ARG A CB  1 
ATOM 2327 C CG  . ARG B 2 22  ? 125.286 151.427 144.021 1.00 67.43  ? 10  ARG A CG  1 
ATOM 2328 C CD  . ARG B 2 22  ? 125.751 152.483 143.032 1.00 65.73  ? 10  ARG A CD  1 
ATOM 2329 N NE  . ARG B 2 22  ? 126.479 153.564 143.687 1.00 60.32  ? 10  ARG A NE  1 
ATOM 2330 C CZ  . ARG B 2 22  ? 125.912 154.530 144.396 1.00 67.06  ? 10  ARG A CZ  1 
ATOM 2331 N NH1 . ARG B 2 22  ? 124.601 154.586 144.565 1.00 64.65  ? 10  ARG A NH1 1 
ATOM 2332 N NH2 . ARG B 2 22  ? 126.679 155.465 144.948 1.00 69.05  ? 10  ARG A NH2 1 
ATOM 2333 N N   . ALA B 2 23  ? 128.232 148.999 146.608 1.00 46.42  ? 11  ALA A N   1 
ATOM 2334 C CA  . ALA B 2 23  ? 129.513 148.376 146.927 1.00 48.70  ? 11  ALA A CA  1 
ATOM 2335 C C   . ALA B 2 23  ? 129.370 146.865 147.080 1.00 47.68  ? 11  ALA A C   1 
ATOM 2336 O O   . ALA B 2 23  ? 130.253 146.104 146.668 1.00 51.28  ? 11  ALA A O   1 
ATOM 2337 C CB  . ALA B 2 23  ? 130.095 148.997 148.193 1.00 49.84  ? 11  ALA A CB  1 
ATOM 2338 N N   . ALA B 2 24  ? 128.264 146.414 147.675 1.00 47.23  ? 12  ALA A N   1 
ATOM 2339 C CA  . ALA B 2 24  ? 128.012 144.981 147.784 1.00 41.45  ? 12  ALA A CA  1 
ATOM 2340 C C   . ALA B 2 24  ? 127.863 144.342 146.410 1.00 49.55  ? 12  ALA A C   1 
ATOM 2341 O O   . ALA B 2 24  ? 128.361 143.236 146.173 1.00 63.66  ? 12  ALA A O   1 
ATOM 2342 C CB  . ALA B 2 24  ? 126.766 144.731 148.631 1.00 46.27  ? 12  ALA A CB  1 
ATOM 2343 N N   . LEU B 2 25  ? 127.173 145.022 145.491 1.00 52.77  ? 13  LEU A N   1 
ATOM 2344 C CA  . LEU B 2 25  ? 127.039 144.508 144.132 1.00 53.53  ? 13  LEU A CA  1 
ATOM 2345 C C   . LEU B 2 25  ? 128.392 144.442 143.433 1.00 49.69  ? 13  LEU A C   1 
ATOM 2346 O O   . LEU B 2 25  ? 128.671 143.495 142.688 1.00 57.94  ? 13  LEU A O   1 
ATOM 2347 C CB  . LEU B 2 25  ? 126.066 145.377 143.338 1.00 57.10  ? 13  LEU A CB  1 
ATOM 2348 C CG  . LEU B 2 25  ? 125.618 144.853 141.974 1.00 58.82  ? 13  LEU A CG  1 
ATOM 2349 C CD1 . LEU B 2 25  ? 125.345 143.360 142.032 1.00 52.05  ? 13  LEU A CD1 1 
ATOM 2350 C CD2 . LEU B 2 25  ? 124.389 145.607 141.494 1.00 58.26  ? 13  LEU A CD2 1 
ATOM 2351 N N   . GLU B 2 26  ? 129.242 145.447 143.656 1.00 49.40  ? 14  GLU A N   1 
ATOM 2352 C CA  . GLU B 2 26  ? 130.589 145.414 143.091 1.00 55.40  ? 14  GLU A CA  1 
ATOM 2353 C C   . GLU B 2 26  ? 131.390 144.240 143.644 1.00 62.37  ? 14  GLU A C   1 
ATOM 2354 O O   . GLU B 2 26  ? 132.114 143.564 142.901 1.00 66.99  ? 14  GLU A O   1 
ATOM 2355 C CB  . GLU B 2 26  ? 131.303 146.735 143.373 1.00 60.05  ? 14  GLU A CB  1 
ATOM 2356 C CG  . GLU B 2 26  ? 132.699 146.828 142.788 1.00 60.74  ? 14  GLU A CG  1 
ATOM 2357 C CD  . GLU B 2 26  ? 133.313 148.202 142.970 1.00 64.88  ? 14  GLU A CD  1 
ATOM 2358 O OE1 . GLU B 2 26  ? 132.634 149.088 143.530 1.00 60.58  ? 14  GLU A OE1 1 
ATOM 2359 O OE2 . GLU B 2 26  ? 134.474 148.396 142.555 1.00 66.94  ? 14  GLU A OE2 1 
ATOM 2360 N N   . ARG B 2 27  ? 131.272 143.983 144.948 1.00 56.80  ? 15  ARG A N   1 
ATOM 2361 C CA  . ARG B 2 27  ? 131.950 142.837 145.548 1.00 46.31  ? 15  ARG A CA  1 
ATOM 2362 C C   . ARG B 2 27  ? 131.442 141.527 144.959 1.00 43.33  ? 15  ARG A C   1 
ATOM 2363 O O   . ARG B 2 27  ? 132.228 140.610 144.687 1.00 50.92  ? 15  ARG A O   1 
ATOM 2364 C CB  . ARG B 2 27  ? 131.759 142.856 147.065 1.00 49.16  ? 15  ARG A CB  1 
ATOM 2365 C CG  . ARG B 2 27  ? 132.329 141.649 147.789 1.00 53.94  ? 15  ARG A CG  1 
ATOM 2366 C CD  . ARG B 2 27  ? 131.989 141.686 149.270 1.00 47.92  ? 15  ARG A CD  1 
ATOM 2367 N NE  . ARG B 2 27  ? 132.336 140.440 149.942 1.00 39.26  ? 15  ARG A NE  1 
ATOM 2368 C CZ  . ARG B 2 27  ? 133.518 140.187 150.486 1.00 47.67  ? 15  ARG A CZ  1 
ATOM 2369 N NH1 . ARG B 2 27  ? 134.497 141.076 150.455 1.00 48.13  ? 15  ARG A NH1 1 
ATOM 2370 N NH2 . ARG B 2 27  ? 133.724 139.013 151.076 1.00 52.32  ? 15  ARG A NH2 1 
ATOM 2371 N N   . SER B 2 28  ? 130.127 141.422 144.757 1.00 41.78  ? 16  SER A N   1 
ATOM 2372 C CA  . SER B 2 28  ? 129.560 140.221 144.154 1.00 45.16  ? 16  SER A CA  1 
ATOM 2373 C C   . SER B 2 28  ? 130.067 140.024 142.731 1.00 54.21  ? 16  SER A C   1 
ATOM 2374 O O   . SER B 2 28  ? 130.369 138.897 142.323 1.00 55.16  ? 16  SER A O   1 
ATOM 2375 C CB  . SER B 2 28  ? 128.034 140.296 144.173 1.00 43.81  ? 16  SER A CB  1 
ATOM 2376 O OG  . SER B 2 28  ? 127.462 139.156 143.559 1.00 51.46  ? 16  SER A OG  1 
ATOM 2377 N N   . LYS B 2 29  ? 130.163 141.107 141.957 1.00 63.22  ? 17  LYS A N   1 
ATOM 2378 C CA  . LYS B 2 29  ? 130.686 140.999 140.597 1.00 60.43  ? 17  LYS A CA  1 
ATOM 2379 C C   . LYS B 2 29  ? 132.150 140.576 140.598 1.00 56.13  ? 17  LYS A C   1 
ATOM 2380 O O   . LYS B 2 29  ? 132.575 139.778 139.752 1.00 61.81  ? 17  LYS A O   1 
ATOM 2381 C CB  . LYS B 2 29  ? 130.506 142.323 139.857 1.00 57.41  ? 17  LYS A CB  1 
ATOM 2382 C CG  . LYS B 2 29  ? 129.260 142.376 138.989 1.00 58.14  ? 17  LYS A CG  1 
ATOM 2383 C CD  . LYS B 2 29  ? 128.618 143.753 139.024 1.00 62.02  ? 17  LYS A CD  1 
ATOM 2384 C CE  . LYS B 2 29  ? 127.507 143.867 137.994 1.00 64.61  ? 17  LYS A CE  1 
ATOM 2385 N NZ  . LYS B 2 29  ? 126.842 145.198 138.037 1.00 59.99  ? 17  LYS A NZ  1 
ATOM 2386 N N   . ALA B 2 30  ? 132.941 141.104 141.535 1.00 50.50  ? 18  ALA A N   1 
ATOM 2387 C CA  . ALA B 2 30  ? 134.336 140.684 141.640 1.00 54.68  ? 18  ALA A CA  1 
ATOM 2388 C C   . ALA B 2 30  ? 134.443 139.203 141.986 1.00 57.65  ? 18  ALA A C   1 
ATOM 2389 O O   . ALA B 2 30  ? 135.279 138.481 141.425 1.00 62.41  ? 18  ALA A O   1 
ATOM 2390 C CB  . ALA B 2 30  ? 135.063 141.533 142.681 1.00 60.25  ? 18  ALA A CB  1 
ATOM 2391 N N   . ILE B 2 31  ? 133.603 138.733 142.911 1.00 60.44  ? 19  ILE A N   1 
ATOM 2392 C CA  . ILE B 2 31  ? 133.604 137.316 143.267 1.00 61.41  ? 19  ILE A CA  1 
ATOM 2393 C C   . ILE B 2 31  ? 133.198 136.466 142.068 1.00 61.40  ? 19  ILE A C   1 
ATOM 2394 O O   . ILE B 2 31  ? 133.758 135.389 141.834 1.00 64.16  ? 19  ILE A O   1 
ATOM 2395 C CB  . ILE B 2 31  ? 132.691 137.069 144.483 1.00 62.37  ? 19  ILE A CB  1 
ATOM 2396 C CG1 . ILE B 2 31  ? 133.396 137.504 145.769 1.00 57.78  ? 19  ILE A CG1 1 
ATOM 2397 C CG2 . ILE B 2 31  ? 132.283 135.608 144.575 1.00 59.13  ? 19  ILE A CG2 1 
ATOM 2398 C CD1 . ILE B 2 31  ? 132.479 137.605 146.962 1.00 49.90  ? 19  ILE A CD1 1 
ATOM 2399 N N   . GLU B 2 32  ? 132.222 136.937 141.289 1.00 58.24  ? 20  GLU A N   1 
ATOM 2400 C CA  . GLU B 2 32  ? 131.811 136.208 140.092 1.00 58.55  ? 20  GLU A CA  1 
ATOM 2401 C C   . GLU B 2 32  ? 132.947 136.118 139.082 1.00 65.86  ? 20  GLU A C   1 
ATOM 2402 O O   . GLU B 2 32  ? 133.158 135.068 138.462 1.00 71.71  ? 20  GLU A O   1 
ATOM 2403 C CB  . GLU B 2 32  ? 130.591 136.880 139.464 1.00 56.23  ? 20  GLU A CB  1 
ATOM 2404 C CG  . GLU B 2 32  ? 129.271 136.215 139.802 1.00 62.55  ? 20  GLU A CG  1 
ATOM 2405 C CD  . GLU B 2 32  ? 128.079 137.085 139.460 1.00 71.56  ? 20  GLU A CD  1 
ATOM 2406 O OE1 . GLU B 2 32  ? 128.105 137.741 138.397 1.00 68.25  ? 20  GLU A OE1 1 
ATOM 2407 O OE2 . GLU B 2 32  ? 127.115 137.115 140.254 1.00 77.69  ? 20  GLU A OE2 1 
ATOM 2408 N N   . LYS B 2 33  ? 133.686 137.215 138.895 1.00 72.75  ? 21  LYS A N   1 
ATOM 2409 C CA  . LYS B 2 33  ? 134.828 137.189 137.986 1.00 70.26  ? 21  LYS A CA  1 
ATOM 2410 C C   . LYS B 2 33  ? 135.892 136.211 138.467 1.00 69.58  ? 21  LYS A C   1 
ATOM 2411 O O   . LYS B 2 33  ? 136.471 135.465 137.666 1.00 71.53  ? 21  LYS A O   1 
ATOM 2412 C CB  . LYS B 2 33  ? 135.419 138.591 137.841 1.00 72.43  ? 21  LYS A CB  1 
ATOM 2413 C CG  . LYS B 2 33  ? 136.046 138.857 136.484 1.00 76.78  ? 21  LYS A CG  1 
ATOM 2414 C CD  . LYS B 2 33  ? 136.754 140.198 136.455 1.00 73.75  ? 21  LYS A CD  1 
ATOM 2415 C CE  . LYS B 2 33  ? 138.051 140.149 137.247 1.00 74.30  ? 21  LYS A CE  1 
ATOM 2416 N NZ  . LYS B 2 33  ? 138.981 139.110 136.725 1.00 75.40  ? 21  LYS A NZ  1 
ATOM 2417 N N   . ASN B 2 34  ? 136.167 136.204 139.774 1.00 70.95  ? 22  ASN A N   1 
ATOM 2418 C CA  . ASN B 2 34  ? 137.139 135.259 140.316 1.00 73.80  ? 22  ASN A CA  1 
ATOM 2419 C C   . ASN B 2 34  ? 136.684 133.820 140.107 1.00 75.43  ? 22  ASN A C   1 
ATOM 2420 O O   . ASN B 2 34  ? 137.490 132.949 139.755 1.00 76.49  ? 22  ASN A O   1 
ATOM 2421 C CB  . ASN B 2 34  ? 137.373 135.540 141.800 1.00 75.21  ? 22  ASN A CB  1 
ATOM 2422 C CG  . ASN B 2 34  ? 138.843 135.543 142.167 1.00 74.48  ? 22  ASN A CG  1 
ATOM 2423 O OD1 . ASN B 2 34  ? 139.678 135.026 141.428 1.00 74.96  ? 22  ASN A OD1 1 
ATOM 2424 N ND2 . ASN B 2 34  ? 139.166 136.132 143.312 1.00 74.46  ? 22  ASN A ND2 1 
ATOM 2425 N N   . LEU B 2 35  ? 135.392 133.553 140.316 1.00 71.56  ? 23  LEU A N   1 
ATOM 2426 C CA  . LEU B 2 35  ? 134.865 132.210 140.098 1.00 69.50  ? 23  LEU A CA  1 
ATOM 2427 C C   . LEU B 2 35  ? 135.001 131.793 138.641 1.00 75.13  ? 23  LEU A C   1 
ATOM 2428 O O   . LEU B 2 35  ? 135.376 130.652 138.347 1.00 74.47  ? 23  LEU A O   1 
ATOM 2429 C CB  . LEU B 2 35  ? 133.401 132.142 140.530 1.00 66.05  ? 23  LEU A CB  1 
ATOM 2430 C CG  . LEU B 2 35  ? 133.112 132.069 142.027 1.00 66.39  ? 23  LEU A CG  1 
ATOM 2431 C CD1 . LEU B 2 35  ? 131.630 131.855 142.254 1.00 67.11  ? 23  LEU A CD1 1 
ATOM 2432 C CD2 . LEU B 2 35  ? 133.923 130.963 142.674 1.00 69.72  ? 23  LEU A CD2 1 
ATOM 2433 N N   . LYS B 2 36  ? 134.693 132.702 137.714 1.00 82.86  ? 24  LYS A N   1 
ATOM 2434 C CA  . LYS B 2 36  ? 134.808 132.373 136.297 1.00 81.30  ? 24  LYS A CA  1 
ATOM 2435 C C   . LYS B 2 36  ? 136.255 132.098 135.909 1.00 81.25  ? 24  LYS A C   1 
ATOM 2436 O O   . LYS B 2 36  ? 136.535 131.161 135.153 1.00 81.26  ? 24  LYS A O   1 
ATOM 2437 C CB  . LYS B 2 36  ? 134.228 133.499 135.442 1.00 84.45  ? 24  LYS A CB  1 
ATOM 2438 C CG  . LYS B 2 36  ? 133.983 133.105 133.994 1.00 88.13  ? 24  LYS A CG  1 
ATOM 2439 C CD  . LYS B 2 36  ? 133.155 131.831 133.900 1.00 87.70  ? 24  LYS A CD  1 
ATOM 2440 C CE  . LYS B 2 36  ? 132.148 131.901 132.762 1.00 84.24  ? 24  LYS A CE  1 
ATOM 2441 N NZ  . LYS B 2 36  ? 132.800 131.779 131.429 1.00 82.43  ? 24  LYS A NZ  1 
ATOM 2442 N N   . GLU B 2 37  ? 137.192 132.904 136.418 1.00 86.06  ? 25  GLU A N   1 
ATOM 2443 C CA  . GLU B 2 37  ? 138.600 132.665 136.116 1.00 87.37  ? 25  GLU A CA  1 
ATOM 2444 C C   . GLU B 2 37  ? 139.064 131.326 136.679 1.00 87.12  ? 25  GLU A C   1 
ATOM 2445 O O   . GLU B 2 37  ? 139.786 130.576 136.008 1.00 89.04  ? 25  GLU A O   1 
ATOM 2446 C CB  . GLU B 2 37  ? 139.458 133.810 136.655 1.00 88.13  ? 25  GLU A CB  1 
ATOM 2447 C CG  . GLU B 2 37  ? 140.801 133.375 137.223 1.00 87.98  ? 25  GLU A CG  1 
ATOM 2448 C CD  . GLU B 2 37  ? 141.533 134.503 137.922 1.00 90.72  ? 25  GLU A CD  1 
ATOM 2449 O OE1 . GLU B 2 37  ? 141.119 134.882 139.036 1.00 90.11  ? 25  GLU A OE1 1 
ATOM 2450 O OE2 . GLU B 2 37  ? 142.524 135.010 137.356 1.00 92.94  ? 25  GLU A OE2 1 
ATOM 2451 N N   . ASP B 2 38  ? 138.651 131.003 137.908 1.00 84.04  ? 26  ASP A N   1 
ATOM 2452 C CA  . ASP B 2 38  ? 139.034 129.726 138.502 1.00 84.80  ? 26  ASP A CA  1 
ATOM 2453 C C   . ASP B 2 38  ? 138.448 128.557 137.721 1.00 84.30  ? 26  ASP A C   1 
ATOM 2454 O O   . ASP B 2 38  ? 139.103 127.522 137.553 1.00 84.59  ? 26  ASP A O   1 
ATOM 2455 C CB  . ASP B 2 38  ? 138.592 129.672 139.964 1.00 85.21  ? 26  ASP A CB  1 
ATOM 2456 C CG  . ASP B 2 38  ? 139.657 130.184 140.914 1.00 86.11  ? 26  ASP A CG  1 
ATOM 2457 O OD1 . ASP B 2 38  ? 140.813 129.721 140.818 1.00 85.73  ? 26  ASP A OD1 1 
ATOM 2458 O OD2 . ASP B 2 38  ? 139.339 131.049 141.756 1.00 85.47  ? 26  ASP A OD2 1 
ATOM 2459 N N   . GLY B 2 39  ? 137.211 128.700 137.242 1.00 81.19  ? 27  GLY A N   1 
ATOM 2460 C CA  . GLY B 2 39  ? 136.620 127.654 136.425 1.00 80.89  ? 27  GLY A CA  1 
ATOM 2461 C C   . GLY B 2 39  ? 137.319 127.492 135.089 1.00 82.69  ? 27  GLY A C   1 
ATOM 2462 O O   . GLY B 2 39  ? 137.466 126.374 134.588 1.00 84.33  ? 27  GLY A O   1 
ATOM 2463 N N   . ILE B 2 40  ? 137.748 128.604 134.488 1.00 85.30  ? 28  ILE A N   1 
ATOM 2464 C CA  . ILE B 2 40  ? 138.511 128.532 133.244 1.00 83.57  ? 28  ILE A CA  1 
ATOM 2465 C C   . ILE B 2 40  ? 139.825 127.797 133.474 1.00 78.76  ? 28  ILE A C   1 
ATOM 2466 O O   . ILE B 2 40  ? 140.219 126.928 132.687 1.00 80.45  ? 28  ILE A O   1 
ATOM 2467 C CB  . ILE B 2 40  ? 138.743 129.942 132.671 1.00 81.64  ? 28  ILE A CB  1 
ATOM 2468 C CG1 . ILE B 2 40  ? 137.443 130.505 132.096 1.00 82.76  ? 28  ILE A CG1 1 
ATOM 2469 C CG2 . ILE B 2 40  ? 139.833 129.920 131.610 1.00 78.84  ? 28  ILE A CG2 1 
ATOM 2470 C CD1 . ILE B 2 40  ? 136.876 129.687 130.957 1.00 79.38  ? 28  ILE A CD1 1 
ATOM 2471 N N   . SER B 2 41  ? 140.517 128.125 134.567 1.00 77.71  ? 29  SER A N   1 
ATOM 2472 C CA  . SER B 2 41  ? 141.762 127.439 134.891 1.00 79.04  ? 29  SER A CA  1 
ATOM 2473 C C   . SER B 2 41  ? 141.551 125.994 135.327 1.00 80.61  ? 29  SER A C   1 
ATOM 2474 O O   . SER B 2 41  ? 142.531 125.249 135.426 1.00 79.33  ? 29  SER A O   1 
ATOM 2475 C CB  . SER B 2 41  ? 142.512 128.198 135.985 1.00 83.65  ? 29  SER A CB  1 
ATOM 2476 O OG  . SER B 2 41  ? 143.822 127.685 136.151 1.00 83.13  ? 29  SER A OG  1 
ATOM 2477 N N   . ALA B 2 42  ? 140.312 125.582 135.591 1.00 84.25  ? 30  ALA A N   1 
ATOM 2478 C CA  . ALA B 2 42  ? 140.015 124.238 136.068 1.00 83.05  ? 30  ALA A CA  1 
ATOM 2479 C C   . ALA B 2 42  ? 139.513 123.314 134.967 1.00 80.40  ? 30  ALA A C   1 
ATOM 2480 O O   . ALA B 2 42  ? 139.053 122.207 135.264 1.00 80.69  ? 30  ALA A O   1 
ATOM 2481 C CB  . ALA B 2 42  ? 138.992 124.295 137.204 1.00 83.90  ? 30  ALA A CB  1 
ATOM 2482 N N   . ALA B 2 43  ? 139.583 123.739 133.707 1.00 83.05  ? 31  ALA A N   1 
ATOM 2483 C CA  . ALA B 2 43  ? 139.189 122.898 132.586 1.00 83.36  ? 31  ALA A CA  1 
ATOM 2484 C C   . ALA B 2 43  ? 140.377 122.299 131.847 1.00 80.89  ? 31  ALA A C   1 
ATOM 2485 O O   . ALA B 2 43  ? 140.182 121.412 131.009 1.00 80.57  ? 31  ALA A O   1 
ATOM 2486 C CB  . ALA B 2 43  ? 138.327 123.694 131.599 1.00 81.11  ? 31  ALA A CB  1 
ATOM 2487 N N   . LYS B 2 44  ? 141.596 122.758 132.138 1.00 77.53  ? 32  LYS A N   1 
ATOM 2488 C CA  . LYS B 2 44  ? 142.772 122.222 131.463 1.00 79.55  ? 32  LYS A CA  1 
ATOM 2489 C C   . LYS B 2 44  ? 143.111 120.818 131.946 1.00 79.01  ? 32  LYS A C   1 
ATOM 2490 O O   . LYS B 2 44  ? 143.639 120.010 131.174 1.00 82.98  ? 32  LYS A O   1 
ATOM 2491 C CB  . LYS B 2 44  ? 143.961 123.161 131.672 1.00 82.14  ? 32  LYS A CB  1 
ATOM 2492 C CG  . LYS B 2 44  ? 145.233 122.744 130.953 1.00 80.81  ? 32  LYS A CG  1 
ATOM 2493 C CD  . LYS B 2 44  ? 146.462 123.263 131.681 1.00 79.68  ? 32  LYS A CD  1 
ATOM 2494 C CE  . LYS B 2 44  ? 146.975 122.251 132.690 1.00 77.64  ? 32  LYS A CE  1 
ATOM 2495 N NZ  . LYS B 2 44  ? 148.461 122.225 132.745 1.00 78.89  ? 32  LYS A NZ  1 
ATOM 2496 N N   . ASP B 2 45  ? 142.808 120.504 133.203 1.00 72.77  ? 33  ASP A N   1 
ATOM 2497 C CA  . ASP B 2 45  ? 143.186 119.219 133.768 1.00 71.03  ? 33  ASP A CA  1 
ATOM 2498 C C   . ASP B 2 45  ? 142.269 118.099 133.278 1.00 74.52  ? 33  ASP A C   1 
ATOM 2499 O O   . ASP B 2 45  ? 141.156 118.328 132.796 1.00 71.52  ? 33  ASP A O   1 
ATOM 2500 C CB  . ASP B 2 45  ? 143.207 119.291 135.301 1.00 72.04  ? 33  ASP A CB  1 
ATOM 2501 C CG  . ASP B 2 45  ? 141.816 119.404 135.923 1.00 78.95  ? 33  ASP A CG  1 
ATOM 2502 O OD1 . ASP B 2 45  ? 140.807 119.514 135.197 1.00 81.60  ? 33  ASP A OD1 1 
ATOM 2503 O OD2 . ASP B 2 45  ? 141.735 119.383 137.169 1.00 75.67  ? 33  ASP A OD2 1 
ATOM 2504 N N   . VAL B 2 46  ? 142.770 116.871 133.391 1.00 64.77  ? 34  VAL A N   1 
ATOM 2505 C CA  . VAL B 2 46  ? 142.034 115.665 133.031 1.00 60.55  ? 34  VAL A CA  1 
ATOM 2506 C C   . VAL B 2 46  ? 141.908 114.803 134.278 1.00 62.54  ? 34  VAL A C   1 
ATOM 2507 O O   . VAL B 2 46  ? 142.915 114.480 134.918 1.00 63.46  ? 34  VAL A O   1 
ATOM 2508 C CB  . VAL B 2 46  ? 142.728 114.893 131.895 1.00 50.77  ? 34  VAL A CB  1 
ATOM 2509 C CG1 . VAL B 2 46  ? 141.994 113.599 131.612 1.00 55.47  ? 34  VAL A CG1 1 
ATOM 2510 C CG2 . VAL B 2 46  ? 142.799 115.749 130.643 1.00 51.65  ? 34  VAL A CG2 1 
ATOM 2511 N N   . LYS B 2 47  ? 140.677 114.433 134.620 1.00 49.29  ? 35  LYS A N   1 
ATOM 2512 C CA  . LYS B 2 47  ? 140.385 113.712 135.854 1.00 47.62  ? 35  LYS A CA  1 
ATOM 2513 C C   . LYS B 2 47  ? 140.211 112.232 135.532 1.00 48.10  ? 35  LYS A C   1 
ATOM 2514 O O   . LYS B 2 47  ? 139.284 111.852 134.811 1.00 58.45  ? 35  LYS A O   1 
ATOM 2515 C CB  . LYS B 2 47  ? 139.138 114.283 136.523 1.00 56.44  ? 35  LYS A CB  1 
ATOM 2516 C CG  . LYS B 2 47  ? 139.392 115.560 137.307 1.00 64.10  ? 35  LYS A CG  1 
ATOM 2517 C CD  . LYS B 2 47  ? 138.219 115.909 138.206 1.00 59.08  ? 35  LYS A CD  1 
ATOM 2518 C CE  . LYS B 2 47  ? 137.077 116.506 137.405 1.00 60.49  ? 35  LYS A CE  1 
ATOM 2519 N NZ  . LYS B 2 47  ? 137.464 117.795 136.769 1.00 57.36  ? 35  LYS A NZ  1 
ATOM 2520 N N   . LEU B 2 48  ? 141.100 111.402 136.070 1.00 41.45  ? 36  LEU A N   1 
ATOM 2521 C CA  . LEU B 2 48  ? 141.061 109.963 135.872 1.00 42.02  ? 36  LEU A CA  1 
ATOM 2522 C C   . LEU B 2 48  ? 140.888 109.258 137.210 1.00 42.49  ? 36  LEU A C   1 
ATOM 2523 O O   . LEU B 2 48  ? 141.239 109.789 138.267 1.00 51.91  ? 36  LEU A O   1 
ATOM 2524 C CB  . LEU B 2 48  ? 142.331 109.459 135.177 1.00 40.42  ? 36  LEU A CB  1 
ATOM 2525 C CG  . LEU B 2 48  ? 142.632 110.067 133.809 1.00 39.91  ? 36  LEU A CG  1 
ATOM 2526 C CD1 . LEU B 2 48  ? 144.033 109.713 133.360 1.00 46.47  ? 36  LEU A CD1 1 
ATOM 2527 C CD2 . LEU B 2 48  ? 141.615 109.591 132.794 1.00 41.39  ? 36  LEU A CD2 1 
ATOM 2528 N N   . LEU B 2 49  ? 140.340 108.050 137.153 1.00 41.45  ? 37  LEU A N   1 
ATOM 2529 C CA  . LEU B 2 49  ? 140.082 107.239 138.334 1.00 36.99  ? 37  LEU A CA  1 
ATOM 2530 C C   . LEU B 2 49  ? 140.952 105.992 138.291 1.00 33.12  ? 37  LEU A C   1 
ATOM 2531 O O   . LEU B 2 49  ? 141.024 105.317 137.260 1.00 43.60  ? 37  LEU A O   1 
ATOM 2532 C CB  . LEU B 2 49  ? 138.603 106.855 138.414 1.00 38.30  ? 37  LEU A CB  1 
ATOM 2533 C CG  . LEU B 2 49  ? 138.139 106.048 139.628 1.00 37.74  ? 37  LEU A CG  1 
ATOM 2534 C CD1 . LEU B 2 49  ? 138.540 106.741 140.911 1.00 44.68  ? 37  LEU A CD1 1 
ATOM 2535 C CD2 . LEU B 2 49  ? 136.638 105.831 139.589 1.00 34.29  ? 37  LEU A CD2 1 
ATOM 2536 N N   . LEU B 2 50  ? 141.613 105.695 139.404 1.00 38.96  ? 38  LEU A N   1 
ATOM 2537 C CA  . LEU B 2 50  ? 142.436 104.502 139.533 1.00 35.11  ? 38  LEU A CA  1 
ATOM 2538 C C   . LEU B 2 50  ? 141.683 103.436 140.315 1.00 45.91  ? 38  LEU A C   1 
ATOM 2539 O O   . LEU B 2 50  ? 141.027 103.733 141.317 1.00 56.00  ? 38  LEU A O   1 
ATOM 2540 C CB  . LEU B 2 50  ? 143.760 104.820 140.229 1.00 37.04  ? 38  LEU A CB  1 
ATOM 2541 C CG  . LEU B 2 50  ? 144.954 105.068 139.310 1.00 41.47  ? 38  LEU A CG  1 
ATOM 2542 C CD1 . LEU B 2 50  ? 146.106 105.691 140.076 1.00 48.26  ? 38  LEU A CD1 1 
ATOM 2543 C CD2 . LEU B 2 50  ? 145.384 103.762 138.680 1.00 40.56  ? 38  LEU A CD2 1 
ATOM 2544 N N   . LEU B 2 51  ? 141.783 102.193 139.853 1.00 47.36  ? 39  LEU A N   1 
ATOM 2545 C CA  . LEU B 2 51  ? 141.064 101.093 140.476 1.00 44.50  ? 39  LEU A CA  1 
ATOM 2546 C C   . LEU B 2 51  ? 141.841 99.803  140.261 1.00 51.69  ? 39  LEU A C   1 
ATOM 2547 O O   . LEU B 2 51  ? 142.738 99.728  139.419 1.00 56.62  ? 39  LEU A O   1 
ATOM 2548 C CB  . LEU B 2 51  ? 139.643 100.968 139.918 1.00 46.09  ? 39  LEU A CB  1 
ATOM 2549 C CG  . LEU B 2 51  ? 138.556 101.672 140.729 1.00 49.70  ? 39  LEU A CG  1 
ATOM 2550 C CD1 . LEU B 2 51  ? 137.248 101.689 139.967 1.00 50.40  ? 39  LEU A CD1 1 
ATOM 2551 C CD2 . LEU B 2 51  ? 138.381 100.995 142.077 1.00 56.50  ? 39  LEU A CD2 1 
ATOM 2552 N N   . GLY B 2 52  ? 141.486 98.787  141.041 1.00 70.10  ? 40  GLY A N   1 
ATOM 2553 C CA  . GLY B 2 52  ? 142.137 97.497  140.939 1.00 71.34  ? 40  GLY A CA  1 
ATOM 2554 C C   . GLY B 2 52  ? 142.348 96.830  142.281 1.00 73.07  ? 40  GLY A C   1 
ATOM 2555 O O   . GLY B 2 52  ? 142.119 97.442  143.329 1.00 74.50  ? 40  GLY A O   1 
ATOM 2556 N N   . ALA B 2 53  ? 142.783 95.574  142.263 1.00 92.64  ? 41  ALA A N   1 
ATOM 2557 C CA  . ALA B 2 53  ? 143.029 94.851  143.499 1.00 97.84  ? 41  ALA A CA  1 
ATOM 2558 C C   . ALA B 2 53  ? 144.284 95.381  144.189 1.00 100.88 ? 41  ALA A C   1 
ATOM 2559 O O   . ALA B 2 53  ? 145.114 96.069  143.590 1.00 97.66  ? 41  ALA A O   1 
ATOM 2560 C CB  . ALA B 2 53  ? 143.169 93.354  143.228 1.00 96.90  ? 41  ALA A CB  1 
ATOM 2561 N N   . ASP B 2 54  ? 144.409 95.056  145.473 1.00 110.76 ? 42  ASP A N   1 
ATOM 2562 C CA  . ASP B 2 54  ? 145.563 95.490  146.243 1.00 107.79 ? 42  ASP A CA  1 
ATOM 2563 C C   . ASP B 2 54  ? 146.832 94.804  145.749 1.00 109.47 ? 42  ASP A C   1 
ATOM 2564 O O   . ASP B 2 54  ? 146.801 93.683  145.235 1.00 109.41 ? 42  ASP A O   1 
ATOM 2565 C CB  . ASP B 2 54  ? 145.356 95.200  147.730 1.00 107.54 ? 42  ASP A CB  1 
ATOM 2566 C CG  . ASP B 2 54  ? 145.050 96.451  148.530 1.00 110.15 ? 42  ASP A CG  1 
ATOM 2567 O OD1 . ASP B 2 54  ? 145.103 97.556  147.950 1.00 109.96 ? 42  ASP A OD1 1 
ATOM 2568 O OD2 . ASP B 2 54  ? 144.759 96.330  149.739 1.00 110.97 ? 42  ASP A OD2 1 
ATOM 2569 N N   . ASN B 2 55  ? 147.959 95.503  145.908 1.00 108.79 ? 43  ASN A N   1 
ATOM 2570 C CA  . ASN B 2 55  ? 149.273 95.016  145.486 1.00 107.60 ? 43  ASN A CA  1 
ATOM 2571 C C   . ASN B 2 55  ? 149.308 94.693  143.995 1.00 106.83 ? 43  ASN A C   1 
ATOM 2572 O O   . ASN B 2 55  ? 149.998 93.765  143.564 1.00 108.97 ? 43  ASN A O   1 
ATOM 2573 C CB  . ASN B 2 55  ? 149.709 93.798  146.307 1.00 106.71 ? 43  ASN A CB  1 
ATOM 2574 C CG  . ASN B 2 55  ? 151.216 93.670  146.403 1.00 108.20 ? 43  ASN A CG  1 
ATOM 2575 O OD1 . ASN B 2 55  ? 151.955 94.373  145.713 1.00 109.82 ? 43  ASN A OD1 1 
ATOM 2576 N ND2 . ASN B 2 55  ? 151.680 92.769  147.260 1.00 107.32 ? 43  ASN A ND2 1 
ATOM 2577 N N   . SER B 2 56  ? 148.561 95.451  143.196 1.00 96.68  ? 44  SER A N   1 
ATOM 2578 C CA  . SER B 2 56  ? 148.554 95.298  141.749 1.00 96.16  ? 44  SER A CA  1 
ATOM 2579 C C   . SER B 2 56  ? 149.341 96.394  141.043 1.00 97.50  ? 44  SER A C   1 
ATOM 2580 O O   . SER B 2 56  ? 149.251 96.516  139.818 1.00 96.22  ? 44  SER A O   1 
ATOM 2581 C CB  . SER B 2 56  ? 147.117 95.269  141.226 1.00 93.63  ? 44  SER A CB  1 
ATOM 2582 O OG  . SER B 2 56  ? 146.415 96.443  141.596 1.00 89.47  ? 44  SER A OG  1 
ATOM 2583 N N   . GLY B 2 57  ? 150.111 97.188  141.783 1.00 94.46  ? 45  GLY A N   1 
ATOM 2584 C CA  . GLY B 2 57  ? 150.816 98.303  141.186 1.00 90.99  ? 45  GLY A CA  1 
ATOM 2585 C C   . GLY B 2 57  ? 149.949 99.500  140.877 1.00 86.33  ? 45  GLY A C   1 
ATOM 2586 O O   . GLY B 2 57  ? 150.322 100.319 140.033 1.00 87.03  ? 45  GLY A O   1 
ATOM 2587 N N   . LYS B 2 58  ? 148.799 99.629  141.540 1.00 80.04  ? 46  LYS A N   1 
ATOM 2588 C CA  . LYS B 2 58  ? 147.871 100.719 141.269 1.00 79.72  ? 46  LYS A CA  1 
ATOM 2589 C C   . LYS B 2 58  ? 148.404 102.077 141.705 1.00 84.43  ? 46  LYS A C   1 
ATOM 2590 O O   . LYS B 2 58  ? 147.791 103.096 141.371 1.00 87.98  ? 46  LYS A O   1 
ATOM 2591 C CB  . LYS B 2 58  ? 146.531 100.443 141.952 1.00 82.09  ? 46  LYS A CB  1 
ATOM 2592 C CG  . LYS B 2 58  ? 146.624 100.308 143.462 1.00 83.50  ? 46  LYS A CG  1 
ATOM 2593 C CD  . LYS B 2 58  ? 145.295 99.879  144.061 1.00 85.18  ? 46  LYS A CD  1 
ATOM 2594 C CE  . LYS B 2 58  ? 144.270 100.994 143.983 1.00 83.67  ? 46  LYS A CE  1 
ATOM 2595 N NZ  . LYS B 2 58  ? 143.110 100.751 144.884 1.00 83.42  ? 46  LYS A NZ  1 
ATOM 2596 N N   . SER B 2 59  ? 149.505 102.119 142.453 1.00 95.63  ? 47  SER A N   1 
ATOM 2597 C CA  . SER B 2 59  ? 150.124 103.372 142.861 1.00 94.48  ? 47  SER A CA  1 
ATOM 2598 C C   . SER B 2 59  ? 151.502 103.581 142.248 1.00 94.81  ? 47  SER A C   1 
ATOM 2599 O O   . SER B 2 59  ? 152.169 104.566 142.581 1.00 93.83  ? 47  SER A O   1 
ATOM 2600 C CB  . SER B 2 59  ? 150.226 103.439 144.389 1.00 94.27  ? 47  SER A CB  1 
ATOM 2601 O OG  . SER B 2 59  ? 151.103 102.444 144.888 1.00 94.59  ? 47  SER A OG  1 
ATOM 2602 N N   . THR B 2 60  ? 151.946 102.688 141.367 1.00 94.14  ? 48  THR A N   1 
ATOM 2603 C CA  . THR B 2 60  ? 153.284 102.733 140.781 1.00 92.57  ? 48  THR A CA  1 
ATOM 2604 C C   . THR B 2 60  ? 153.212 102.590 139.266 1.00 93.97  ? 48  THR A C   1 
ATOM 2605 O O   . THR B 2 60  ? 153.943 101.807 138.655 1.00 95.33  ? 48  THR A O   1 
ATOM 2606 C CB  . THR B 2 60  ? 154.182 101.646 141.368 1.00 93.42  ? 48  THR A CB  1 
ATOM 2607 O OG1 . THR B 2 60  ? 153.629 100.357 141.076 1.00 91.98  ? 48  THR A OG1 1 
ATOM 2608 C CG2 . THR B 2 60  ? 154.317 101.809 142.876 1.00 92.19  ? 48  THR A CG2 1 
ATOM 2609 N N   . ILE B 2 61  ? 152.321 103.351 138.632 1.00 91.48  ? 49  ILE A N   1 
ATOM 2610 C CA  . ILE B 2 61  ? 152.208 103.306 137.176 1.00 90.29  ? 49  ILE A CA  1 
ATOM 2611 C C   . ILE B 2 61  ? 153.283 104.168 136.526 1.00 93.04  ? 49  ILE A C   1 
ATOM 2612 O O   . ILE B 2 61  ? 154.123 103.674 135.765 1.00 94.99  ? 49  ILE A O   1 
ATOM 2613 C CB  . ILE B 2 61  ? 150.800 103.738 136.727 1.00 88.20  ? 49  ILE A CB  1 
ATOM 2614 C CG1 . ILE B 2 61  ? 149.739 102.840 137.358 1.00 89.29  ? 49  ILE A CG1 1 
ATOM 2615 C CG2 . ILE B 2 61  ? 150.693 103.706 135.215 1.00 92.07  ? 49  ILE A CG2 1 
ATOM 2616 C CD1 . ILE B 2 61  ? 148.998 103.495 138.489 1.00 91.68  ? 49  ILE A CD1 1 
ATOM 2617 N N   . VAL B 2 62  ? 153.273 105.466 136.817 1.00 99.43  ? 50  VAL A N   1 
ATOM 2618 C CA  . VAL B 2 62  ? 154.219 106.414 136.240 1.00 100.29 ? 50  VAL A CA  1 
ATOM 2619 C C   . VAL B 2 62  ? 155.235 106.805 137.304 1.00 102.45 ? 50  VAL A C   1 
ATOM 2620 O O   . VAL B 2 62  ? 154.871 107.074 138.456 1.00 102.58 ? 50  VAL A O   1 
ATOM 2621 C CB  . VAL B 2 62  ? 153.496 107.649 135.674 1.00 99.16  ? 50  VAL A CB  1 
ATOM 2622 C CG1 . VAL B 2 62  ? 152.647 107.257 134.481 1.00 98.33  ? 50  VAL A CG1 1 
ATOM 2623 C CG2 . VAL B 2 62  ? 152.627 108.301 136.736 1.00 99.44  ? 50  VAL A CG2 1 
ATOM 2624 N N   . LYS B 2 63  ? 156.516 106.813 136.927 1.00 115.70 ? 51  LYS A N   1 
ATOM 2625 C CA  . LYS B 2 63  ? 157.561 107.202 137.866 1.00 117.36 ? 51  LYS A CA  1 
ATOM 2626 C C   . LYS B 2 63  ? 157.509 108.685 138.204 1.00 117.92 ? 51  LYS A C   1 
ATOM 2627 O O   . LYS B 2 63  ? 158.015 109.086 139.258 1.00 120.16 ? 51  LYS A O   1 
ATOM 2628 C CB  . LYS B 2 63  ? 158.936 106.838 137.305 1.00 117.99 ? 51  LYS A CB  1 
ATOM 2629 C CG  . LYS B 2 63  ? 159.185 105.341 137.217 1.00 118.05 ? 51  LYS A CG  1 
ATOM 2630 C CD  . LYS B 2 63  ? 160.643 105.003 137.477 1.00 116.91 ? 51  LYS A CD  1 
ATOM 2631 C CE  . LYS B 2 63  ? 160.800 103.561 137.932 1.00 118.16 ? 51  LYS A CE  1 
ATOM 2632 N NZ  . LYS B 2 63  ? 160.184 102.604 136.971 1.00 119.02 ? 51  LYS A NZ  1 
ATOM 2633 N N   . GLN B 2 64  ? 156.909 109.503 137.339 1.00 108.74 ? 52  GLN A N   1 
ATOM 2634 C CA  . GLN B 2 64  ? 156.709 110.926 137.611 1.00 110.04 ? 52  GLN A CA  1 
ATOM 2635 C C   . GLN B 2 64  ? 155.464 111.054 138.482 1.00 108.97 ? 52  GLN A C   1 
ATOM 2636 O O   . GLN B 2 64  ? 154.369 111.387 138.024 1.00 109.81 ? 52  GLN A O   1 
ATOM 2637 C CB  . GLN B 2 64  ? 156.574 111.706 136.310 1.00 108.36 ? 52  GLN A CB  1 
ATOM 2638 C CG  . GLN B 2 64  ? 157.710 111.477 135.329 1.00 107.48 ? 52  GLN A CG  1 
ATOM 2639 C CD  . GLN B 2 64  ? 157.357 111.909 133.920 1.00 108.72 ? 52  GLN A CD  1 
ATOM 2640 O OE1 . GLN B 2 64  ? 156.220 112.293 133.643 1.00 108.28 ? 52  GLN A OE1 1 
ATOM 2641 N NE2 . GLN B 2 64  ? 158.330 111.845 133.019 1.00 108.37 ? 52  GLN A NE2 1 
ATOM 2642 N N   . MET B 2 65  ? 155.639 110.776 139.774 1.00 108.73 ? 53  MET A N   1 
ATOM 2643 C CA  . MET B 2 65  ? 154.482 110.623 140.651 1.00 108.06 ? 53  MET A CA  1 
ATOM 2644 C C   . MET B 2 65  ? 153.944 111.977 141.123 1.00 109.41 ? 53  MET A C   1 
ATOM 2645 O O   . MET B 2 65  ? 152.813 112.344 140.787 1.00 109.40 ? 53  MET A O   1 
ATOM 2646 C CB  . MET B 2 65  ? 154.839 109.657 141.798 1.00 112.25 ? 53  MET A CB  1 
ATOM 2647 C CG  . MET B 2 65  ? 155.584 110.185 143.023 1.00 110.85 ? 53  MET A CG  1 
ATOM 2648 S SD  . MET B 2 65  ? 154.517 111.007 144.214 1.00 112.64 ? 53  MET A SD  1 
ATOM 2649 C CE  . MET B 2 65  ? 153.604 109.598 144.841 1.00 109.14 ? 53  MET A CE  1 
ATOM 2650 N N   . LYS B 2 66  ? 154.747 112.754 141.851 1.00 107.33 ? 54  LYS A N   1 
ATOM 2651 C CA  . LYS B 2 66  ? 154.372 114.092 142.319 1.00 108.77 ? 54  LYS A CA  1 
ATOM 2652 C C   . LYS B 2 66  ? 152.963 114.098 142.923 1.00 106.22 ? 54  LYS A C   1 
ATOM 2653 O O   . LYS B 2 66  ? 152.024 114.677 142.377 1.00 104.42 ? 54  LYS A O   1 
ATOM 2654 C CB  . LYS B 2 66  ? 154.483 115.116 141.185 1.00 108.42 ? 54  LYS A CB  1 
ATOM 2655 C CG  . LYS B 2 66  ? 155.689 114.931 140.280 1.00 103.81 ? 54  LYS A CG  1 
ATOM 2656 C CD  . LYS B 2 66  ? 155.824 116.093 139.309 1.00 105.22 ? 54  LYS A CD  1 
ATOM 2657 C CE  . LYS B 2 66  ? 154.886 115.937 138.124 1.00 105.32 ? 54  LYS A CE  1 
ATOM 2658 N NZ  . LYS B 2 66  ? 154.955 114.572 137.540 1.00 105.06 ? 54  LYS A NZ  1 
ATOM 2659 N N   . ILE B 2 67  ? 152.841 113.408 144.062 1.00 97.75  ? 55  ILE A N   1 
ATOM 2660 C CA  . ILE B 2 67  ? 151.529 113.180 144.674 1.00 100.10 ? 55  ILE A CA  1 
ATOM 2661 C C   . ILE B 2 67  ? 150.792 114.499 144.888 1.00 101.56 ? 55  ILE A C   1 
ATOM 2662 O O   . ILE B 2 67  ? 149.729 114.739 144.305 1.00 106.94 ? 55  ILE A O   1 
ATOM 2663 C CB  . ILE B 2 67  ? 151.671 112.392 145.989 1.00 102.47 ? 55  ILE A CB  1 
ATOM 2664 C CG1 . ILE B 2 67  ? 150.382 112.475 146.812 1.00 101.25 ? 55  ILE A CG1 1 
ATOM 2665 C CG2 . ILE B 2 67  ? 152.884 112.862 146.790 1.00 106.57 ? 55  ILE A CG2 1 
ATOM 2666 C CD1 . ILE B 2 67  ? 150.321 111.478 147.946 1.00 99.18  ? 55  ILE A CD1 1 
ATOM 2667 N N   . ILE B 2 68  ? 151.354 115.379 145.711 1.00 105.67 ? 56  ILE A N   1 
ATOM 2668 C CA  . ILE B 2 68  ? 150.714 116.653 146.014 1.00 108.57 ? 56  ILE A CA  1 
ATOM 2669 C C   . ILE B 2 68  ? 151.690 117.574 146.736 1.00 110.82 ? 56  ILE A C   1 
ATOM 2670 O O   . ILE B 2 68  ? 151.514 118.792 146.753 1.00 110.51 ? 56  ILE A O   1 
ATOM 2671 C CB  . ILE B 2 68  ? 149.431 116.450 146.847 1.00 106.19 ? 56  ILE A CB  1 
ATOM 2672 C CG1 . ILE B 2 68  ? 148.377 117.491 146.466 1.00 105.79 ? 56  ILE A CG1 1 
ATOM 2673 C CG2 . ILE B 2 68  ? 149.740 116.512 148.336 1.00 108.21 ? 56  ILE A CG2 1 
ATOM 2674 C CD1 . ILE B 2 68  ? 147.001 117.196 147.017 1.00 106.91 ? 56  ILE A CD1 1 
ATOM 2675 N N   . THR B 2 79  ? 144.832 108.640 155.465 1.00 82.69  ? 183 THR A N   1 
ATOM 2676 C CA  . THR B 2 79  ? 143.660 107.845 155.118 1.00 83.98  ? 183 THR A CA  1 
ATOM 2677 C C   . THR B 2 79  ? 142.575 108.729 154.509 1.00 83.98  ? 183 THR A C   1 
ATOM 2678 O O   . THR B 2 79  ? 142.209 109.759 155.075 1.00 83.34  ? 183 THR A O   1 
ATOM 2679 C CB  . THR B 2 79  ? 143.095 107.104 156.348 1.00 82.90  ? 183 THR A CB  1 
ATOM 2680 O OG1 . THR B 2 79  ? 144.040 106.123 156.793 1.00 83.47  ? 183 THR A OG1 1 
ATOM 2681 C CG2 . THR B 2 79  ? 141.783 106.412 156.004 1.00 78.61  ? 183 THR A CG2 1 
ATOM 2682 N N   . GLY B 2 80  ? 142.068 108.320 153.350 1.00 84.00  ? 184 GLY A N   1 
ATOM 2683 C CA  . GLY B 2 80  ? 141.060 109.087 152.646 1.00 79.50  ? 184 GLY A CA  1 
ATOM 2684 C C   . GLY B 2 80  ? 141.129 108.878 151.149 1.00 85.59  ? 184 GLY A C   1 
ATOM 2685 O O   . GLY B 2 80  ? 141.100 107.739 150.674 1.00 90.67  ? 184 GLY A O   1 
ATOM 2686 N N   . ILE B 2 81  ? 141.219 109.969 150.395 1.00 74.40  ? 185 ILE A N   1 
ATOM 2687 C CA  . ILE B 2 81  ? 141.376 109.919 148.947 1.00 71.85  ? 185 ILE A CA  1 
ATOM 2688 C C   . ILE B 2 81  ? 142.755 110.459 148.594 1.00 78.01  ? 185 ILE A C   1 
ATOM 2689 O O   . ILE B 2 81  ? 143.204 111.465 149.157 1.00 81.56  ? 185 ILE A O   1 
ATOM 2690 C CB  . ILE B 2 81  ? 140.258 110.701 148.228 1.00 70.01  ? 185 ILE A CB  1 
ATOM 2691 C CG1 . ILE B 2 81  ? 140.404 110.572 146.713 1.00 71.95  ? 185 ILE A CG1 1 
ATOM 2692 C CG2 . ILE B 2 81  ? 140.242 112.163 148.658 1.00 73.77  ? 185 ILE A CG2 1 
ATOM 2693 C CD1 . ILE B 2 81  ? 139.159 110.946 145.956 1.00 74.25  ? 185 ILE A CD1 1 
ATOM 2694 N N   . VAL B 2 82  ? 143.437 109.774 147.680 1.00 74.56  ? 186 VAL A N   1 
ATOM 2695 C CA  . VAL B 2 82  ? 144.812 110.089 147.311 1.00 74.33  ? 186 VAL A CA  1 
ATOM 2696 C C   . VAL B 2 82  ? 144.822 110.621 145.886 1.00 71.86  ? 186 VAL A C   1 
ATOM 2697 O O   . VAL B 2 82  ? 144.283 109.982 144.975 1.00 76.11  ? 186 VAL A O   1 
ATOM 2698 C CB  . VAL B 2 82  ? 145.724 108.858 147.445 1.00 70.81  ? 186 VAL A CB  1 
ATOM 2699 C CG1 . VAL B 2 82  ? 147.180 109.258 147.280 1.00 75.19  ? 186 VAL A CG1 1 
ATOM 2700 C CG2 . VAL B 2 82  ? 145.497 108.177 148.784 1.00 69.11  ? 186 VAL A CG2 1 
ATOM 2701 N N   . GLU B 2 83  ? 145.437 111.784 145.694 1.00 65.38  ? 187 GLU A N   1 
ATOM 2702 C CA  . GLU B 2 83  ? 145.480 112.450 144.401 1.00 65.66  ? 187 GLU A CA  1 
ATOM 2703 C C   . GLU B 2 83  ? 146.902 112.446 143.856 1.00 70.22  ? 187 GLU A C   1 
ATOM 2704 O O   . GLU B 2 83  ? 147.866 112.629 144.606 1.00 77.29  ? 187 GLU A O   1 
ATOM 2705 C CB  . GLU B 2 83  ? 144.965 113.888 144.512 1.00 67.12  ? 187 GLU A CB  1 
ATOM 2706 C CG  . GLU B 2 83  ? 145.094 114.702 143.236 1.00 66.85  ? 187 GLU A CG  1 
ATOM 2707 C CD  . GLU B 2 83  ? 143.993 115.733 143.089 1.00 70.11  ? 187 GLU A CD  1 
ATOM 2708 O OE1 . GLU B 2 83  ? 142.970 115.614 143.794 1.00 75.20  ? 187 GLU A OE1 1 
ATOM 2709 O OE2 . GLU B 2 83  ? 144.148 116.659 142.266 1.00 69.73  ? 187 GLU A OE2 1 
ATOM 2710 N N   . THR B 2 84  ? 147.023 112.226 142.549 1.00 73.61  ? 188 THR A N   1 
ATOM 2711 C CA  . THR B 2 84  ? 148.294 112.267 141.838 1.00 69.38  ? 188 THR A CA  1 
ATOM 2712 C C   . THR B 2 84  ? 148.113 113.133 140.601 1.00 71.23  ? 188 THR A C   1 
ATOM 2713 O O   . THR B 2 84  ? 147.197 112.894 139.810 1.00 78.03  ? 188 THR A O   1 
ATOM 2714 C CB  . THR B 2 84  ? 148.753 110.857 141.451 1.00 72.99  ? 188 THR A CB  1 
ATOM 2715 O OG1 . THR B 2 84  ? 148.881 110.054 142.631 1.00 73.10  ? 188 THR A OG1 1 
ATOM 2716 C CG2 . THR B 2 84  ? 150.077 110.903 140.722 1.00 73.61  ? 188 THR A CG2 1 
ATOM 2717 N N   . HIS B 2 85  ? 148.980 114.129 140.430 1.00 78.61  ? 189 HIS A N   1 
ATOM 2718 C CA  . HIS B 2 85  ? 148.745 115.197 139.460 1.00 85.10  ? 189 HIS A CA  1 
ATOM 2719 C C   . HIS B 2 85  ? 149.932 115.362 138.515 1.00 89.35  ? 189 HIS A C   1 
ATOM 2720 O O   . HIS B 2 85  ? 150.431 116.468 138.295 1.00 93.15  ? 189 HIS A O   1 
ATOM 2721 C CB  . HIS B 2 85  ? 148.433 116.515 140.166 1.00 85.07  ? 189 HIS A CB  1 
ATOM 2722 C CG  . HIS B 2 85  ? 149.506 116.973 141.104 1.00 85.21  ? 189 HIS A CG  1 
ATOM 2723 N ND1 . HIS B 2 85  ? 150.790 117.252 140.689 1.00 83.66  ? 189 HIS A ND1 1 
ATOM 2724 C CD2 . HIS B 2 85  ? 149.481 117.215 142.436 1.00 89.17  ? 189 HIS A CD2 1 
ATOM 2725 C CE1 . HIS B 2 85  ? 151.512 117.638 141.725 1.00 88.32  ? 189 HIS A CE1 1 
ATOM 2726 N NE2 . HIS B 2 85  ? 150.742 117.624 142.798 1.00 92.05  ? 189 HIS A NE2 1 
ATOM 2727 N N   . PHE B 2 86  ? 150.407 114.262 137.940 1.00 81.94  ? 190 PHE A N   1 
ATOM 2728 C CA  . PHE B 2 86  ? 151.462 114.360 136.941 1.00 77.41  ? 190 PHE A CA  1 
ATOM 2729 C C   . PHE B 2 86  ? 150.926 114.991 135.660 1.00 77.64  ? 190 PHE A C   1 
ATOM 2730 O O   . PHE B 2 86  ? 149.731 114.923 135.360 1.00 79.64  ? 190 PHE A O   1 
ATOM 2731 C CB  . PHE B 2 86  ? 152.056 112.982 136.648 1.00 80.03  ? 190 PHE A CB  1 
ATOM 2732 C CG  . PHE B 2 86  ? 151.465 112.302 135.447 1.00 79.22  ? 190 PHE A CG  1 
ATOM 2733 C CD1 . PHE B 2 86  ? 150.220 111.701 135.514 1.00 78.09  ? 190 PHE A CD1 1 
ATOM 2734 C CD2 . PHE B 2 86  ? 152.162 112.253 134.251 1.00 80.37  ? 190 PHE A CD2 1 
ATOM 2735 C CE1 . PHE B 2 86  ? 149.680 111.071 134.410 1.00 76.85  ? 190 PHE A CE1 1 
ATOM 2736 C CE2 . PHE B 2 86  ? 151.624 111.627 133.145 1.00 80.28  ? 190 PHE A CE2 1 
ATOM 2737 C CZ  . PHE B 2 86  ? 150.382 111.035 133.224 1.00 77.19  ? 190 PHE A CZ  1 
ATOM 2738 N N   . THR B 2 87  ? 151.824 115.618 134.903 1.00 77.39  ? 191 THR A N   1 
ATOM 2739 C CA  . THR B 2 87  ? 151.466 116.332 133.686 1.00 80.83  ? 191 THR A CA  1 
ATOM 2740 C C   . THR B 2 87  ? 152.271 115.805 132.504 1.00 80.21  ? 191 THR A C   1 
ATOM 2741 O O   . THR B 2 87  ? 153.366 115.258 132.663 1.00 80.99  ? 191 THR A O   1 
ATOM 2742 C CB  . THR B 2 87  ? 151.690 117.843 133.838 1.00 78.82  ? 191 THR A CB  1 
ATOM 2743 O OG1 . THR B 2 87  ? 151.198 118.520 132.675 1.00 80.23  ? 191 THR A OG1 1 
ATOM 2744 C CG2 . THR B 2 87  ? 153.167 118.152 134.012 1.00 78.91  ? 191 THR A CG2 1 
ATOM 2745 N N   . PHE B 2 88  ? 151.711 115.977 131.307 1.00 70.12  ? 192 PHE A N   1 
ATOM 2746 C CA  . PHE B 2 88  ? 152.332 115.461 130.093 1.00 69.64  ? 192 PHE A CA  1 
ATOM 2747 C C   . PHE B 2 88  ? 151.745 116.180 128.887 1.00 77.19  ? 192 PHE A C   1 
ATOM 2748 O O   . PHE B 2 88  ? 150.524 116.330 128.792 1.00 78.77  ? 192 PHE A O   1 
ATOM 2749 C CB  . PHE B 2 88  ? 152.112 113.949 129.974 1.00 68.08  ? 192 PHE A CB  1 
ATOM 2750 C CG  . PHE B 2 88  ? 152.949 113.294 128.915 1.00 73.19  ? 192 PHE A CG  1 
ATOM 2751 C CD1 . PHE B 2 88  ? 154.306 113.103 129.107 1.00 77.19  ? 192 PHE A CD1 1 
ATOM 2752 C CD2 . PHE B 2 88  ? 152.376 112.857 127.734 1.00 71.16  ? 192 PHE A CD2 1 
ATOM 2753 C CE1 . PHE B 2 88  ? 155.078 112.496 128.136 1.00 77.31  ? 192 PHE A CE1 1 
ATOM 2754 C CE2 . PHE B 2 88  ? 153.144 112.248 126.759 1.00 72.49  ? 192 PHE A CE2 1 
ATOM 2755 C CZ  . PHE B 2 88  ? 154.496 112.068 126.961 1.00 73.94  ? 192 PHE A CZ  1 
ATOM 2756 N N   . LYS B 2 89  ? 152.617 116.614 127.974 1.00 75.54  ? 193 LYS A N   1 
ATOM 2757 C CA  . LYS B 2 89  ? 152.216 117.254 126.717 1.00 67.61  ? 193 LYS A CA  1 
ATOM 2758 C C   . LYS B 2 89  ? 151.272 118.429 126.959 1.00 67.70  ? 193 LYS A C   1 
ATOM 2759 O O   . LYS B 2 89  ? 150.237 118.571 126.305 1.00 72.48  ? 193 LYS A O   1 
ATOM 2760 C CB  . LYS B 2 89  ? 151.586 116.239 125.761 1.00 69.17  ? 193 LYS A CB  1 
ATOM 2761 C CG  . LYS B 2 89  ? 152.578 115.287 125.119 1.00 70.10  ? 193 LYS A CG  1 
ATOM 2762 C CD  . LYS B 2 89  ? 152.940 115.738 123.716 1.00 72.25  ? 193 LYS A CD  1 
ATOM 2763 C CE  . LYS B 2 89  ? 153.712 114.661 122.974 1.00 73.27  ? 193 LYS A CE  1 
ATOM 2764 N NZ  . LYS B 2 89  ? 152.862 113.479 122.668 1.00 72.21  ? 193 LYS A NZ  1 
ATOM 2765 N N   . ASN B 2 90  ? 151.643 119.278 127.918 1.00 73.66  ? 194 ASN A N   1 
ATOM 2766 C CA  . ASN B 2 90  ? 150.866 120.469 128.265 1.00 76.51  ? 194 ASN A CA  1 
ATOM 2767 C C   . ASN B 2 90  ? 149.434 120.103 128.651 1.00 76.85  ? 194 ASN A C   1 
ATOM 2768 O O   . ASN B 2 90  ? 148.487 120.846 128.384 1.00 74.91  ? 194 ASN A O   1 
ATOM 2769 C CB  . ASN B 2 90  ? 150.879 121.490 127.124 1.00 83.43  ? 194 ASN A CB  1 
ATOM 2770 C CG  . ASN B 2 90  ? 151.879 122.606 127.350 1.00 84.27  ? 194 ASN A CG  1 
ATOM 2771 O OD1 . ASN B 2 90  ? 152.891 122.421 128.026 1.00 82.23  ? 194 ASN A OD1 1 
ATOM 2772 N ND2 . ASN B 2 90  ? 151.603 123.773 126.779 1.00 79.40  ? 194 ASN A ND2 1 
ATOM 2773 N N   . LEU B 2 91  ? 149.277 118.944 129.287 1.00 76.47  ? 195 LEU A N   1 
ATOM 2774 C CA  . LEU B 2 91  ? 147.974 118.455 129.715 1.00 76.99  ? 195 LEU A CA  1 
ATOM 2775 C C   . LEU B 2 91  ? 148.124 117.841 131.097 1.00 73.07  ? 195 LEU A C   1 
ATOM 2776 O O   . LEU B 2 91  ? 149.051 117.061 131.333 1.00 66.41  ? 195 LEU A O   1 
ATOM 2777 C CB  . LEU B 2 91  ? 147.416 117.430 128.721 1.00 70.17  ? 195 LEU A CB  1 
ATOM 2778 C CG  . LEU B 2 91  ? 145.906 117.204 128.726 1.00 70.51  ? 195 LEU A CG  1 
ATOM 2779 C CD1 . LEU B 2 91  ? 145.177 118.515 128.500 1.00 71.64  ? 195 LEU A CD1 1 
ATOM 2780 C CD2 . LEU B 2 91  ? 145.522 116.190 127.661 1.00 73.82  ? 195 LEU A CD2 1 
ATOM 2781 N N   . HIS B 2 92  ? 147.217 118.192 132.002 1.00 72.07  ? 196 HIS A N   1 
ATOM 2782 C CA  . HIS B 2 92  ? 147.313 117.798 133.400 1.00 70.00  ? 196 HIS A CA  1 
ATOM 2783 C C   . HIS B 2 92  ? 146.404 116.606 133.666 1.00 71.51  ? 196 HIS A C   1 
ATOM 2784 O O   . HIS B 2 92  ? 145.204 116.658 133.379 1.00 73.20  ? 196 HIS A O   1 
ATOM 2785 C CB  . HIS B 2 92  ? 146.937 118.964 134.315 1.00 76.16  ? 196 HIS A CB  1 
ATOM 2786 C CG  . HIS B 2 92  ? 147.532 118.875 135.686 1.00 79.80  ? 196 HIS A CG  1 
ATOM 2787 N ND1 . HIS B 2 92  ? 147.031 119.575 136.762 1.00 76.54  ? 196 HIS A ND1 1 
ATOM 2788 C CD2 . HIS B 2 92  ? 148.592 118.174 136.154 1.00 74.71  ? 196 HIS A CD2 1 
ATOM 2789 C CE1 . HIS B 2 92  ? 147.754 119.307 137.834 1.00 72.25  ? 196 HIS A CE1 1 
ATOM 2790 N NE2 . HIS B 2 92  ? 148.707 118.460 137.492 1.00 73.21  ? 196 HIS A NE2 1 
ATOM 2791 N N   . PHE B 2 93  ? 146.977 115.539 134.215 1.00 64.47  ? 197 PHE A N   1 
ATOM 2792 C CA  . PHE B 2 93  ? 146.240 114.331 134.561 1.00 63.49  ? 197 PHE A CA  1 
ATOM 2793 C C   . PHE B 2 93  ? 146.189 114.209 136.076 1.00 61.24  ? 197 PHE A C   1 
ATOM 2794 O O   . PHE B 2 93  ? 147.233 114.223 136.737 1.00 63.80  ? 197 PHE A O   1 
ATOM 2795 C CB  . PHE B 2 93  ? 146.893 113.091 133.951 1.00 69.95  ? 197 PHE A CB  1 
ATOM 2796 C CG  . PHE B 2 93  ? 146.919 113.092 132.452 1.00 64.92  ? 197 PHE A CG  1 
ATOM 2797 C CD1 . PHE B 2 93  ? 145.756 112.923 131.725 1.00 60.19  ? 197 PHE A CD1 1 
ATOM 2798 C CD2 . PHE B 2 93  ? 148.110 113.254 131.769 1.00 60.70  ? 197 PHE A CD2 1 
ATOM 2799 C CE1 . PHE B 2 93  ? 145.779 112.924 130.349 1.00 58.15  ? 197 PHE A CE1 1 
ATOM 2800 C CE2 . PHE B 2 93  ? 148.138 113.255 130.395 1.00 62.50  ? 197 PHE A CE2 1 
ATOM 2801 C CZ  . PHE B 2 93  ? 146.971 113.089 129.684 1.00 61.36  ? 197 PHE A CZ  1 
ATOM 2802 N N   . ARG B 2 94  ? 144.982 114.088 136.620 1.00 60.07  ? 198 ARG A N   1 
ATOM 2803 C CA  . ARG B 2 94  ? 144.770 113.932 138.055 1.00 59.10  ? 198 ARG A CA  1 
ATOM 2804 C C   . ARG B 2 94  ? 144.203 112.541 138.306 1.00 57.11  ? 198 ARG A C   1 
ATOM 2805 O O   . ARG B 2 94  ? 143.071 112.246 137.910 1.00 65.88  ? 198 ARG A O   1 
ATOM 2806 C CB  . ARG B 2 94  ? 143.840 115.019 138.587 1.00 61.18  ? 198 ARG A CB  1 
ATOM 2807 C CG  . ARG B 2 94  ? 144.558 116.297 138.981 1.00 67.16  ? 198 ARG A CG  1 
ATOM 2808 C CD  . ARG B 2 94  ? 143.612 117.485 139.002 1.00 65.23  ? 198 ARG A CD  1 
ATOM 2809 N NE  . ARG B 2 94  ? 143.005 117.683 140.312 1.00 64.82  ? 198 ARG A NE  1 
ATOM 2810 C CZ  . ARG B 2 94  ? 141.743 118.038 140.505 1.00 63.12  ? 198 ARG A CZ  1 
ATOM 2811 N NH1 . ARG B 2 94  ? 140.920 118.245 139.490 1.00 63.64  ? 198 ARG A NH1 1 
ATOM 2812 N NH2 . ARG B 2 94  ? 141.294 118.190 141.748 1.00 59.63  ? 198 ARG A NH2 1 
ATOM 2813 N N   . LEU B 2 95  ? 144.989 111.689 138.960 1.00 48.13  ? 199 LEU A N   1 
ATOM 2814 C CA  . LEU B 2 95  ? 144.600 110.311 139.241 1.00 47.03  ? 199 LEU A CA  1 
ATOM 2815 C C   . LEU B 2 95  ? 144.089 110.231 140.674 1.00 58.14  ? 199 LEU A C   1 
ATOM 2816 O O   . LEU B 2 95  ? 144.860 110.394 141.624 1.00 67.50  ? 199 LEU A O   1 
ATOM 2817 C CB  . LEU B 2 95  ? 145.774 109.358 139.030 1.00 50.04  ? 199 LEU A CB  1 
ATOM 2818 C CG  . LEU B 2 95  ? 146.632 109.546 137.778 1.00 58.61  ? 199 LEU A CG  1 
ATOM 2819 C CD1 . LEU B 2 95  ? 147.711 108.480 137.711 1.00 57.88  ? 199 LEU A CD1 1 
ATOM 2820 C CD2 . LEU B 2 95  ? 145.775 109.510 136.530 1.00 58.65  ? 199 LEU A CD2 1 
ATOM 2821 N N   . PHE B 2 96  ? 142.793 109.972 140.829 1.00 53.76  ? 200 PHE A N   1 
ATOM 2822 C CA  . PHE B 2 96  ? 142.178 109.831 142.145 1.00 48.84  ? 200 PHE A CA  1 
ATOM 2823 C C   . PHE B 2 96  ? 142.196 108.360 142.536 1.00 43.19  ? 200 PHE A C   1 
ATOM 2824 O O   . PHE B 2 96  ? 141.439 107.556 141.986 1.00 49.14  ? 200 PHE A O   1 
ATOM 2825 C CB  . PHE B 2 96  ? 140.752 110.373 142.140 1.00 44.64  ? 200 PHE A CB  1 
ATOM 2826 C CG  . PHE B 2 96  ? 140.633 111.770 141.611 1.00 46.71  ? 200 PHE A CG  1 
ATOM 2827 C CD1 . PHE B 2 96  ? 141.217 112.830 142.279 1.00 51.36  ? 200 PHE A CD1 1 
ATOM 2828 C CD2 . PHE B 2 96  ? 139.930 112.024 140.449 1.00 54.35  ? 200 PHE A CD2 1 
ATOM 2829 C CE1 . PHE B 2 96  ? 141.104 114.116 141.793 1.00 58.14  ? 200 PHE A CE1 1 
ATOM 2830 C CE2 . PHE B 2 96  ? 139.814 113.306 139.961 1.00 47.85  ? 200 PHE A CE2 1 
ATOM 2831 C CZ  . PHE B 2 96  ? 140.402 114.353 140.632 1.00 51.23  ? 200 PHE A CZ  1 
ATOM 2832 N N   . ASP B 2 97  ? 143.055 108.006 143.486 1.00 53.48  ? 201 ASP A N   1 
ATOM 2833 C CA  . ASP B 2 97  ? 143.129 106.641 143.994 1.00 55.81  ? 201 ASP A CA  1 
ATOM 2834 C C   . ASP B 2 97  ? 142.151 106.515 145.157 1.00 64.44  ? 201 ASP A C   1 
ATOM 2835 O O   . ASP B 2 97  ? 142.361 107.102 146.222 1.00 67.57  ? 201 ASP A O   1 
ATOM 2836 C CB  . ASP B 2 97  ? 144.554 106.299 144.419 1.00 62.84  ? 201 ASP A CB  1 
ATOM 2837 C CG  . ASP B 2 97  ? 144.771 104.809 144.576 1.00 66.47  ? 201 ASP A CG  1 
ATOM 2838 O OD1 . ASP B 2 97  ? 143.781 104.053 144.495 1.00 66.70  ? 201 ASP A OD1 1 
ATOM 2839 O OD2 . ASP B 2 97  ? 145.931 104.392 144.774 1.00 65.67  ? 201 ASP A OD2 1 
ATOM 2840 N N   . VAL B 2 98  ? 141.083 105.746 144.952 1.00 65.29  ? 202 VAL A N   1 
ATOM 2841 C CA  . VAL B 2 98  ? 139.996 105.649 145.921 1.00 64.18  ? 202 VAL A CA  1 
ATOM 2842 C C   . VAL B 2 98  ? 140.321 104.607 146.982 1.00 71.49  ? 202 VAL A C   1 
ATOM 2843 O O   . VAL B 2 98  ? 139.474 104.276 147.819 1.00 72.52  ? 202 VAL A O   1 
ATOM 2844 C CB  . VAL B 2 98  ? 138.666 105.318 145.223 1.00 59.97  ? 202 VAL A CB  1 
ATOM 2845 C CG1 . VAL B 2 98  ? 138.106 106.555 144.548 1.00 65.65  ? 202 VAL A CG1 1 
ATOM 2846 C CG2 . VAL B 2 98  ? 138.862 104.196 144.216 1.00 61.63  ? 202 VAL A CG2 1 
ATOM 2847 N N   . GLY B 2 99  ? 141.542 104.079 146.952 1.00 81.36  ? 203 GLY A N   1 
ATOM 2848 C CA  . GLY B 2 99  ? 141.920 103.058 147.908 1.00 81.54  ? 203 GLY A CA  1 
ATOM 2849 C C   . GLY B 2 99  ? 141.966 103.590 149.328 1.00 83.92  ? 203 GLY A C   1 
ATOM 2850 O O   . GLY B 2 99  ? 142.222 104.768 149.574 1.00 77.40  ? 203 GLY A O   1 
ATOM 2851 N N   . GLY B 2 100 ? 141.709 102.693 150.278 1.00 103.41 ? 204 GLY A N   1 
ATOM 2852 C CA  . GLY B 2 100 ? 141.733 103.028 151.684 1.00 100.47 ? 204 GLY A CA  1 
ATOM 2853 C C   . GLY B 2 100 ? 140.408 103.467 152.269 1.00 97.97  ? 204 GLY A C   1 
ATOM 2854 O O   . GLY B 2 100 ? 140.302 103.578 153.497 1.00 101.07 ? 204 GLY A O   1 
ATOM 2855 N N   . GLN B 2 101 ? 139.395 103.723 151.437 1.00 89.10  ? 205 GLN A N   1 
ATOM 2856 C CA  . GLN B 2 101 ? 138.102 104.150 151.962 1.00 93.67  ? 205 GLN A CA  1 
ATOM 2857 C C   . GLN B 2 101 ? 137.436 103.042 152.770 1.00 95.06  ? 205 GLN A C   1 
ATOM 2858 O O   . GLN B 2 101 ? 136.912 103.294 153.861 1.00 95.01  ? 205 GLN A O   1 
ATOM 2859 C CB  . GLN B 2 101 ? 137.196 104.603 150.819 1.00 94.16  ? 205 GLN A CB  1 
ATOM 2860 C CG  . GLN B 2 101 ? 136.104 105.565 151.248 1.00 93.67  ? 205 GLN A CG  1 
ATOM 2861 C CD  . GLN B 2 101 ? 136.536 107.012 151.139 1.00 91.55  ? 205 GLN A CD  1 
ATOM 2862 O OE1 . GLN B 2 101 ? 136.974 107.461 150.081 1.00 90.55  ? 205 GLN A OE1 1 
ATOM 2863 N NE2 . GLN B 2 101 ? 136.418 107.749 152.236 1.00 89.78  ? 205 GLN A NE2 1 
ATOM 2864 N N   . ARG B 2 102 ? 137.451 101.813 152.249 1.00 111.64 ? 206 ARG A N   1 
ATOM 2865 C CA  . ARG B 2 102 ? 136.912 100.641 152.946 1.00 111.10 ? 206 ARG A CA  1 
ATOM 2866 C C   . ARG B 2 102 ? 135.454 100.845 153.355 1.00 110.90 ? 206 ARG A C   1 
ATOM 2867 O O   . ARG B 2 102 ? 135.040 100.469 154.453 1.00 112.87 ? 206 ARG A O   1 
ATOM 2868 C CB  . ARG B 2 102 ? 137.771 100.282 154.161 1.00 111.59 ? 206 ARG A CB  1 
ATOM 2869 C CG  . ARG B 2 102 ? 139.216 99.928  153.830 1.00 111.38 ? 206 ARG A CG  1 
ATOM 2870 C CD  . ARG B 2 102 ? 139.347 98.498  153.322 1.00 111.45 ? 206 ARG A CD  1 
ATOM 2871 N NE  . ARG B 2 102 ? 139.045 98.381  151.900 1.00 113.70 ? 206 ARG A NE  1 
ATOM 2872 C CZ  . ARG B 2 102 ? 139.902 98.652  150.925 1.00 113.41 ? 206 ARG A CZ  1 
ATOM 2873 N NH1 . ARG B 2 102 ? 141.137 99.051  151.181 1.00 111.54 ? 206 ARG A NH1 1 
ATOM 2874 N NH2 . ARG B 2 102 ? 139.511 98.517  149.661 1.00 111.65 ? 206 ARG A NH2 1 
ATOM 2875 N N   . SER B 2 103 ? 134.667 101.445 152.464 1.00 113.19 ? 207 SER A N   1 
ATOM 2876 C CA  . SER B 2 103 ? 133.249 101.661 152.726 1.00 113.37 ? 207 SER A CA  1 
ATOM 2877 C C   . SER B 2 103 ? 132.404 101.121 151.579 1.00 114.12 ? 207 SER A C   1 
ATOM 2878 O O   . SER B 2 103 ? 132.925 100.459 150.676 1.00 113.84 ? 207 SER A O   1 
ATOM 2879 C CB  . SER B 2 103 ? 132.963 103.148 152.946 1.00 112.17 ? 207 SER A CB  1 
ATOM 2880 O OG  . SER B 2 103 ? 133.593 103.619 154.124 1.00 113.08 ? 207 SER A OG  1 
ATOM 2881 N N   . GLU B 2 104 ? 131.102 101.394 151.606 1.00 114.33 ? 208 GLU A N   1 
ATOM 2882 C CA  . GLU B 2 104 ? 130.214 100.969 150.531 1.00 115.24 ? 208 GLU A CA  1 
ATOM 2883 C C   . GLU B 2 104 ? 130.380 101.906 149.342 1.00 113.44 ? 208 GLU A C   1 
ATOM 2884 O O   . GLU B 2 104 ? 130.167 103.117 149.463 1.00 110.68 ? 208 GLU A O   1 
ATOM 2885 C CB  . GLU B 2 104 ? 128.764 100.948 151.009 1.00 114.43 ? 208 GLU A CB  1 
ATOM 2886 C CG  . GLU B 2 104 ? 127.804 100.240 150.061 1.00 114.99 ? 208 GLU A CG  1 
ATOM 2887 C CD  . GLU B 2 104 ? 128.195 98.799  149.791 1.00 114.92 ? 208 GLU A CD  1 
ATOM 2888 O OE1 . GLU B 2 104 ? 128.676 98.123  150.726 1.00 115.80 ? 208 GLU A OE1 1 
ATOM 2889 O OE2 . GLU B 2 104 ? 128.022 98.340  148.643 1.00 114.24 ? 208 GLU A OE2 1 
ATOM 2890 N N   . ARG B 2 105 ? 130.760 101.345 148.193 1.00 103.83 ? 209 ARG A N   1 
ATOM 2891 C CA  . ARG B 2 105 ? 131.024 102.160 147.015 1.00 104.99 ? 209 ARG A CA  1 
ATOM 2892 C C   . ARG B 2 105 ? 129.767 102.813 146.458 1.00 103.97 ? 209 ARG A C   1 
ATOM 2893 O O   . ARG B 2 105 ? 129.871 103.822 145.755 1.00 105.94 ? 209 ARG A O   1 
ATOM 2894 C CB  . ARG B 2 105 ? 131.694 101.315 145.931 1.00 106.22 ? 209 ARG A CB  1 
ATOM 2895 C CG  . ARG B 2 105 ? 133.193 101.140 146.123 1.00 104.27 ? 209 ARG A CG  1 
ATOM 2896 C CD  . ARG B 2 105 ? 133.840 100.488 144.912 1.00 103.23 ? 209 ARG A CD  1 
ATOM 2897 N NE  . ARG B 2 105 ? 133.264 99.180  144.624 1.00 106.46 ? 209 ARG A NE  1 
ATOM 2898 C CZ  . ARG B 2 105 ? 133.754 98.324  143.738 1.00 106.50 ? 209 ARG A CZ  1 
ATOM 2899 N NH1 . ARG B 2 105 ? 134.837 98.604  143.032 1.00 105.29 ? 209 ARG A NH1 1 
ATOM 2900 N NH2 . ARG B 2 105 ? 133.144 97.156  143.557 1.00 105.35 ? 209 ARG A NH2 1 
ATOM 2901 N N   . LYS B 2 106 ? 128.584 102.279 146.763 1.00 101.41 ? 210 LYS A N   1 
ATOM 2902 C CA  . LYS B 2 106 ? 127.356 102.814 146.188 1.00 102.74 ? 210 LYS A CA  1 
ATOM 2903 C C   . LYS B 2 106 ? 127.024 104.218 146.676 1.00 103.93 ? 210 LYS A C   1 
ATOM 2904 O O   . LYS B 2 106 ? 126.153 104.865 146.085 1.00 106.81 ? 210 LYS A O   1 
ATOM 2905 C CB  . LYS B 2 106 ? 126.181 101.881 146.491 1.00 102.30 ? 210 LYS A CB  1 
ATOM 2906 C CG  . LYS B 2 106 ? 126.469 100.411 146.242 1.00 103.47 ? 210 LYS A CG  1 
ATOM 2907 C CD  . LYS B 2 106 ? 125.188 99.595  146.251 1.00 102.83 ? 210 LYS A CD  1 
ATOM 2908 C CE  . LYS B 2 106 ? 125.213 98.515  145.183 1.00 102.41 ? 210 LYS A CE  1 
ATOM 2909 N NZ  . LYS B 2 106 ? 124.042 97.602  145.291 1.00 103.89 ? 210 LYS A NZ  1 
ATOM 2910 N N   . LYS B 2 107 ? 127.686 104.708 147.724 1.00 85.53  ? 211 LYS A N   1 
ATOM 2911 C CA  . LYS B 2 107 ? 127.318 105.987 148.315 1.00 87.07  ? 211 LYS A CA  1 
ATOM 2912 C C   . LYS B 2 107 ? 128.239 107.138 147.933 1.00 87.14  ? 211 LYS A C   1 
ATOM 2913 O O   . LYS B 2 107 ? 127.830 108.297 148.063 1.00 84.04  ? 211 LYS A O   1 
ATOM 2914 C CB  . LYS B 2 107 ? 127.262 105.868 149.842 1.00 84.05  ? 211 LYS A CB  1 
ATOM 2915 C CG  . LYS B 2 107 ? 126.202 104.894 150.333 1.00 80.96  ? 211 LYS A CG  1 
ATOM 2916 C CD  . LYS B 2 107 ? 124.920 105.048 149.527 1.00 85.47  ? 211 LYS A CD  1 
ATOM 2917 C CE  . LYS B 2 107 ? 123.693 105.075 150.416 1.00 83.44  ? 211 LYS A CE  1 
ATOM 2918 N NZ  . LYS B 2 107 ? 122.572 105.822 149.783 1.00 77.56  ? 211 LYS A NZ  1 
ATOM 2919 N N   . TRP B 2 108 ? 129.459 106.864 147.471 1.00 86.88  ? 212 TRP A N   1 
ATOM 2920 C CA  . TRP B 2 108 ? 130.360 107.934 147.067 1.00 83.22  ? 212 TRP A CA  1 
ATOM 2921 C C   . TRP B 2 108 ? 130.937 107.775 145.668 1.00 82.81  ? 212 TRP A C   1 
ATOM 2922 O O   . TRP B 2 108 ? 131.622 108.693 145.205 1.00 85.71  ? 212 TRP A O   1 
ATOM 2923 C CB  . TRP B 2 108 ? 131.521 108.076 148.064 1.00 81.48  ? 212 TRP A CB  1 
ATOM 2924 C CG  . TRP B 2 108 ? 132.217 106.796 148.381 1.00 84.82  ? 212 TRP A CG  1 
ATOM 2925 C CD1 . TRP B 2 108 ? 132.006 105.996 149.463 1.00 87.92  ? 212 TRP A CD1 1 
ATOM 2926 C CD2 . TRP B 2 108 ? 133.257 106.175 147.618 1.00 87.17  ? 212 TRP A CD2 1 
ATOM 2927 N NE1 . TRP B 2 108 ? 132.842 104.908 149.417 1.00 91.93  ? 212 TRP A NE1 1 
ATOM 2928 C CE2 . TRP B 2 108 ? 133.622 104.995 148.294 1.00 88.13  ? 212 TRP A CE2 1 
ATOM 2929 C CE3 . TRP B 2 108 ? 133.913 106.500 146.428 1.00 85.02  ? 212 TRP A CE3 1 
ATOM 2930 C CZ2 . TRP B 2 108 ? 134.611 104.139 147.819 1.00 84.05  ? 212 TRP A CZ2 1 
ATOM 2931 C CZ3 . TRP B 2 108 ? 134.893 105.650 145.958 1.00 84.72  ? 212 TRP A CZ3 1 
ATOM 2932 C CH2 . TRP B 2 108 ? 135.233 104.483 146.652 1.00 86.66  ? 212 TRP A CH2 1 
ATOM 2933 N N   . ILE B 2 109 ? 130.692 106.656 144.982 1.00 77.09  ? 213 ILE A N   1 
ATOM 2934 C CA  . ILE B 2 109 ? 131.244 106.480 143.644 1.00 77.98  ? 213 ILE A CA  1 
ATOM 2935 C C   . ILE B 2 109 ? 130.627 107.447 142.644 1.00 79.59  ? 213 ILE A C   1 
ATOM 2936 O O   . ILE B 2 109 ? 131.208 107.681 141.579 1.00 81.07  ? 213 ILE A O   1 
ATOM 2937 C CB  . ILE B 2 109 ? 131.073 105.025 143.166 1.00 77.01  ? 213 ILE A CB  1 
ATOM 2938 C CG1 . ILE B 2 109 ? 132.214 104.632 142.225 1.00 74.09  ? 213 ILE A CG1 1 
ATOM 2939 C CG2 . ILE B 2 109 ? 129.724 104.827 142.497 1.00 76.28  ? 213 ILE A CG2 1 
ATOM 2940 C CD1 . ILE B 2 109 ? 133.520 104.360 142.932 1.00 76.96  ? 213 ILE A CD1 1 
ATOM 2941 N N   . HIS B 2 110 ? 129.464 108.022 142.954 1.00 79.23  ? 214 HIS A N   1 
ATOM 2942 C CA  . HIS B 2 110 ? 128.876 109.011 142.061 1.00 79.02  ? 214 HIS A CA  1 
ATOM 2943 C C   . HIS B 2 110 ? 129.594 110.351 142.120 1.00 75.36  ? 214 HIS A C   1 
ATOM 2944 O O   . HIS B 2 110 ? 129.308 111.225 141.295 1.00 73.87  ? 214 HIS A O   1 
ATOM 2945 C CB  . HIS B 2 110 ? 127.387 109.194 142.371 1.00 80.40  ? 214 HIS A CB  1 
ATOM 2946 C CG  . HIS B 2 110 ? 127.099 109.544 143.797 1.00 79.64  ? 214 HIS A CG  1 
ATOM 2947 N ND1 . HIS B 2 110 ? 127.333 110.797 144.319 1.00 78.13  ? 214 HIS A ND1 1 
ATOM 2948 C CD2 . HIS B 2 110 ? 126.583 108.806 144.808 1.00 76.67  ? 214 HIS A CD2 1 
ATOM 2949 C CE1 . HIS B 2 110 ? 126.981 110.814 145.592 1.00 78.01  ? 214 HIS A CE1 1 
ATOM 2950 N NE2 . HIS B 2 110 ? 126.523 109.618 145.913 1.00 78.66  ? 214 HIS A NE2 1 
ATOM 2951 N N   . CYS B 2 111 ? 130.513 110.535 143.071 1.00 69.30  ? 215 CYS A N   1 
ATOM 2952 C CA  . CYS B 2 111 ? 131.348 111.729 143.084 1.00 71.70  ? 215 CYS A CA  1 
ATOM 2953 C C   . CYS B 2 111 ? 132.306 111.772 141.901 1.00 75.12  ? 215 CYS A C   1 
ATOM 2954 O O   . CYS B 2 111 ? 132.817 112.847 141.572 1.00 75.45  ? 215 CYS A O   1 
ATOM 2955 C CB  . CYS B 2 111 ? 132.139 111.808 144.391 1.00 69.89  ? 215 CYS A CB  1 
ATOM 2956 S SG  . CYS B 2 111 ? 131.131 112.034 145.872 1.00 82.02  ? 215 CYS A SG  1 
ATOM 2957 N N   . PHE B 2 112 ? 132.561 110.631 141.260 1.00 69.75  ? 216 PHE A N   1 
ATOM 2958 C CA  . PHE B 2 112 ? 133.481 110.537 140.134 1.00 66.06  ? 216 PHE A CA  1 
ATOM 2959 C C   . PHE B 2 112 ? 132.754 110.276 138.818 1.00 67.82  ? 216 PHE A C   1 
ATOM 2960 O O   . PHE B 2 112 ? 133.298 109.626 137.924 1.00 68.09  ? 216 PHE A O   1 
ATOM 2961 C CB  . PHE B 2 112 ? 134.521 109.446 140.385 1.00 61.71  ? 216 PHE A CB  1 
ATOM 2962 C CG  . PHE B 2 112 ? 135.170 109.525 141.733 1.00 59.41  ? 216 PHE A CG  1 
ATOM 2963 C CD1 . PHE B 2 112 ? 136.276 110.331 141.937 1.00 61.30  ? 216 PHE A CD1 1 
ATOM 2964 C CD2 . PHE B 2 112 ? 134.680 108.789 142.797 1.00 60.66  ? 216 PHE A CD2 1 
ATOM 2965 C CE1 . PHE B 2 112 ? 136.877 110.403 143.176 1.00 59.66  ? 216 PHE A CE1 1 
ATOM 2966 C CE2 . PHE B 2 112 ? 135.276 108.857 144.038 1.00 64.28  ? 216 PHE A CE2 1 
ATOM 2967 C CZ  . PHE B 2 112 ? 136.375 109.665 144.228 1.00 62.37  ? 216 PHE A CZ  1 
ATOM 2968 N N   . GLU B 2 113 ? 131.524 110.777 138.686 1.00 73.58  ? 217 GLU A N   1 
ATOM 2969 C CA  . GLU B 2 113 ? 130.768 110.573 137.454 1.00 66.88  ? 217 GLU A CA  1 
ATOM 2970 C C   . GLU B 2 113 ? 131.427 111.247 136.258 1.00 68.79  ? 217 GLU A C   1 
ATOM 2971 O O   . GLU B 2 113 ? 131.263 110.787 135.123 1.00 74.55  ? 217 GLU A O   1 
ATOM 2972 C CB  . GLU B 2 113 ? 129.343 111.097 137.621 1.00 71.52  ? 217 GLU A CB  1 
ATOM 2973 C CG  . GLU B 2 113 ? 128.396 110.704 136.500 1.00 74.61  ? 217 GLU A CG  1 
ATOM 2974 C CD  . GLU B 2 113 ? 126.979 110.472 136.981 1.00 79.87  ? 217 GLU A CD  1 
ATOM 2975 O OE1 . GLU B 2 113 ? 126.190 111.441 137.003 1.00 81.90  ? 217 GLU A OE1 1 
ATOM 2976 O OE2 . GLU B 2 113 ? 126.650 109.321 137.328 1.00 76.24  ? 217 GLU A OE2 1 
ATOM 2977 N N   . ASP B 2 114 ? 132.175 112.323 136.485 1.00 64.28  ? 218 ASP A N   1 
ATOM 2978 C CA  . ASP B 2 114 ? 132.702 113.148 135.408 1.00 67.55  ? 218 ASP A CA  1 
ATOM 2979 C C   . ASP B 2 114 ? 134.148 112.823 135.055 1.00 64.77  ? 218 ASP A C   1 
ATOM 2980 O O   . ASP B 2 114 ? 134.785 113.597 134.335 1.00 68.95  ? 218 ASP A O   1 
ATOM 2981 C CB  . ASP B 2 114 ? 132.575 114.627 135.776 1.00 71.09  ? 218 ASP A CB  1 
ATOM 2982 C CG  . ASP B 2 114 ? 131.135 115.051 135.994 1.00 76.11  ? 218 ASP A CG  1 
ATOM 2983 O OD1 . ASP B 2 114 ? 130.418 115.263 134.994 1.00 74.84  ? 218 ASP A OD1 1 
ATOM 2984 O OD2 . ASP B 2 114 ? 130.721 115.170 137.166 1.00 75.30  ? 218 ASP A OD2 1 
ATOM 2985 N N   . VAL B 2 115 ? 134.683 111.703 135.545 1.00 55.66  ? 219 VAL A N   1 
ATOM 2986 C CA  . VAL B 2 115 ? 136.054 111.336 135.217 1.00 55.67  ? 219 VAL A CA  1 
ATOM 2987 C C   . VAL B 2 115 ? 136.154 110.992 133.735 1.00 55.70  ? 219 VAL A C   1 
ATOM 2988 O O   . VAL B 2 115 ? 135.223 110.441 133.132 1.00 59.20  ? 219 VAL A O   1 
ATOM 2989 C CB  . VAL B 2 115 ? 136.540 110.167 136.092 1.00 45.56  ? 219 VAL A CB  1 
ATOM 2990 C CG1 . VAL B 2 115 ? 136.586 110.583 137.551 1.00 51.74  ? 219 VAL A CG1 1 
ATOM 2991 C CG2 . VAL B 2 115 ? 135.652 108.950 135.902 1.00 49.01  ? 219 VAL A CG2 1 
ATOM 2992 N N   . THR B 2 116 ? 137.295 111.336 133.136 1.00 49.16  ? 220 THR A N   1 
ATOM 2993 C CA  . THR B 2 116 ? 137.492 111.071 131.714 1.00 45.54  ? 220 THR A CA  1 
ATOM 2994 C C   . THR B 2 116 ? 137.559 109.575 131.430 1.00 46.52  ? 220 THR A C   1 
ATOM 2995 O O   . THR B 2 116 ? 137.013 109.106 130.425 1.00 53.98  ? 220 THR A O   1 
ATOM 2996 C CB  . THR B 2 116 ? 138.758 111.772 131.220 1.00 45.32  ? 220 THR A CB  1 
ATOM 2997 O OG1 . THR B 2 116 ? 138.642 113.182 131.445 1.00 46.19  ? 220 THR A OG1 1 
ATOM 2998 C CG2 . THR B 2 116 ? 138.964 111.526 129.736 1.00 46.89  ? 220 THR A CG2 1 
ATOM 2999 N N   . ALA B 2 117 ? 138.212 108.811 132.300 1.00 34.12  ? 221 ALA A N   1 
ATOM 3000 C CA  . ALA B 2 117 ? 138.383 107.381 132.079 1.00 34.74  ? 221 ALA A CA  1 
ATOM 3001 C C   . ALA B 2 117 ? 138.637 106.700 133.417 1.00 37.24  ? 221 ALA A C   1 
ATOM 3002 O O   . ALA B 2 117 ? 138.767 107.352 134.456 1.00 54.46  ? 221 ALA A O   1 
ATOM 3003 C CB  . ALA B 2 117 ? 139.522 107.107 131.097 1.00 35.88  ? 221 ALA A CB  1 
ATOM 3004 N N   . ILE B 2 118 ? 138.705 105.372 133.378 1.00 31.72  ? 222 ILE A N   1 
ATOM 3005 C CA  . ILE B 2 118 ? 139.044 104.548 134.531 1.00 27.30  ? 222 ILE A CA  1 
ATOM 3006 C C   . ILE B 2 118 ? 140.312 103.781 134.194 1.00 31.95  ? 222 ILE A C   1 
ATOM 3007 O O   . ILE B 2 118 ? 140.369 103.094 133.168 1.00 52.83  ? 222 ILE A O   1 
ATOM 3008 C CB  . ILE B 2 118 ? 137.908 103.573 134.891 1.00 28.91  ? 222 ILE A CB  1 
ATOM 3009 C CG1 . ILE B 2 118 ? 136.558 104.286 134.888 1.00 29.12  ? 222 ILE A CG1 1 
ATOM 3010 C CG2 . ILE B 2 118 ? 138.168 102.928 136.238 1.00 34.08  ? 222 ILE A CG2 1 
ATOM 3011 C CD1 . ILE B 2 118 ? 136.427 105.341 135.944 1.00 49.21  ? 222 ILE A CD1 1 
ATOM 3012 N N   . ILE B 2 119 ? 141.321 103.894 135.046 1.00 29.94  ? 223 ILE A N   1 
ATOM 3013 C CA  . ILE B 2 119 ? 142.572 103.168 134.869 1.00 30.50  ? 223 ILE A CA  1 
ATOM 3014 C C   . ILE B 2 119 ? 142.518 101.939 135.764 1.00 35.22  ? 223 ILE A C   1 
ATOM 3015 O O   . ILE B 2 119 ? 142.618 102.046 136.990 1.00 53.19  ? 223 ILE A O   1 
ATOM 3016 C CB  . ILE B 2 119 ? 143.792 104.041 135.188 1.00 37.11  ? 223 ILE A CB  1 
ATOM 3017 C CG1 . ILE B 2 119 ? 143.856 105.236 134.237 1.00 39.98  ? 223 ILE A CG1 1 
ATOM 3018 C CG2 . ILE B 2 119 ? 145.066 103.223 135.086 1.00 35.89  ? 223 ILE A CG2 1 
ATOM 3019 C CD1 . ILE B 2 119 ? 144.880 106.272 134.634 1.00 34.24  ? 223 ILE A CD1 1 
ATOM 3020 N N   . PHE B 2 120 ? 142.360 100.770 135.154 1.00 42.42  ? 224 PHE A N   1 
ATOM 3021 C CA  . PHE B 2 120 ? 142.261 99.511  135.878 1.00 53.85  ? 224 PHE A CA  1 
ATOM 3022 C C   . PHE B 2 120 ? 143.603 98.795  135.807 1.00 58.84  ? 224 PHE A C   1 
ATOM 3023 O O   . PHE B 2 120 ? 144.114 98.535  134.713 1.00 68.77  ? 224 PHE A O   1 
ATOM 3024 C CB  . PHE B 2 120 ? 141.151 98.637  135.295 1.00 52.38  ? 224 PHE A CB  1 
ATOM 3025 C CG  . PHE B 2 120 ? 140.523 97.712  136.292 1.00 55.72  ? 224 PHE A CG  1 
ATOM 3026 C CD1 . PHE B 2 120 ? 141.075 96.472  136.548 1.00 53.83  ? 224 PHE A CD1 1 
ATOM 3027 C CD2 . PHE B 2 120 ? 139.376 98.082  136.971 1.00 56.48  ? 224 PHE A CD2 1 
ATOM 3028 C CE1 . PHE B 2 120 ? 140.499 95.617  137.464 1.00 53.62  ? 224 PHE A CE1 1 
ATOM 3029 C CE2 . PHE B 2 120 ? 138.795 97.232  137.889 1.00 62.81  ? 224 PHE A CE2 1 
ATOM 3030 C CZ  . PHE B 2 120 ? 139.358 95.997  138.135 1.00 62.36  ? 224 PHE A CZ  1 
ATOM 3031 N N   . CYS B 2 121 ? 144.167 98.478  136.968 1.00 53.89  ? 225 CYS A N   1 
ATOM 3032 C CA  . CYS B 2 121 ? 145.461 97.815  137.061 1.00 57.20  ? 225 CYS A CA  1 
ATOM 3033 C C   . CYS B 2 121 ? 145.250 96.394  137.564 1.00 70.93  ? 225 CYS A C   1 
ATOM 3034 O O   . CYS B 2 121 ? 144.662 96.191  138.631 1.00 80.58  ? 225 CYS A O   1 
ATOM 3035 C CB  . CYS B 2 121 ? 146.402 98.583  137.988 1.00 64.46  ? 225 CYS A CB  1 
ATOM 3036 S SG  . CYS B 2 121 ? 147.077 100.096 137.272 1.00 81.18  ? 225 CYS A SG  1 
ATOM 3037 N N   . VAL B 2 122 ? 145.730 95.419  136.798 1.00 80.46  ? 226 VAL A N   1 
ATOM 3038 C CA  . VAL B 2 122 ? 145.591 94.006  137.126 1.00 73.85  ? 226 VAL A CA  1 
ATOM 3039 C C   . VAL B 2 122 ? 146.978 93.385  137.180 1.00 77.13  ? 226 VAL A C   1 
ATOM 3040 O O   . VAL B 2 122 ? 147.773 93.548  136.247 1.00 82.01  ? 226 VAL A O   1 
ATOM 3041 C CB  . VAL B 2 122 ? 144.707 93.270  136.104 1.00 71.97  ? 226 VAL A CB  1 
ATOM 3042 C CG1 . VAL B 2 122 ? 144.705 91.777  136.381 1.00 76.14  ? 226 VAL A CG1 1 
ATOM 3043 C CG2 . VAL B 2 122 ? 143.300 93.821  136.140 1.00 74.28  ? 226 VAL A CG2 1 
ATOM 3044 N N   . ASP B 2 123 ? 147.265 92.675  138.266 1.00 104.07 ? 227 ASP A N   1 
ATOM 3045 C CA  . ASP B 2 123 ? 148.527 91.967  138.431 1.00 106.87 ? 227 ASP A CA  1 
ATOM 3046 C C   . ASP B 2 123 ? 148.335 90.513  138.018 1.00 106.79 ? 227 ASP A C   1 
ATOM 3047 O O   . ASP B 2 123 ? 147.486 89.810  138.576 1.00 106.89 ? 227 ASP A O   1 
ATOM 3048 C CB  . ASP B 2 123 ? 149.026 92.071  139.872 1.00 108.28 ? 227 ASP A CB  1 
ATOM 3049 C CG  . ASP B 2 123 ? 148.007 91.578  140.881 1.00 110.97 ? 227 ASP A CG  1 
ATOM 3050 O OD1 . ASP B 2 123 ? 146.794 91.673  140.600 1.00 108.04 ? 227 ASP A OD1 1 
ATOM 3051 O OD2 . ASP B 2 123 ? 148.420 91.097  141.957 1.00 111.64 ? 227 ASP A OD2 1 
ATOM 3052 N N   . LEU B 2 124 ? 149.114 90.071  137.033 1.00 112.85 ? 228 LEU A N   1 
ATOM 3053 C CA  . LEU B 2 124 ? 148.970 88.726  136.495 1.00 115.53 ? 228 LEU A CA  1 
ATOM 3054 C C   . LEU B 2 124 ? 149.702 87.672  137.315 1.00 115.53 ? 228 LEU A C   1 
ATOM 3055 O O   . LEU B 2 124 ? 149.470 86.477  137.102 1.00 114.58 ? 228 LEU A O   1 
ATOM 3056 C CB  . LEU B 2 124 ? 149.466 88.686  135.047 1.00 114.10 ? 228 LEU A CB  1 
ATOM 3057 C CG  . LEU B 2 124 ? 148.423 88.877  133.943 1.00 109.34 ? 228 LEU A CG  1 
ATOM 3058 C CD1 . LEU B 2 124 ? 147.715 90.212  134.083 1.00 109.44 ? 228 LEU A CD1 1 
ATOM 3059 C CD2 . LEU B 2 124 ? 149.076 88.767  132.578 1.00 112.84 ? 228 LEU A CD2 1 
ATOM 3060 N N   . SER B 2 125 ? 150.572 88.076  138.242 1.00 124.86 ? 229 SER A N   1 
ATOM 3061 C CA  . SER B 2 125 ? 151.328 87.111  139.028 1.00 126.00 ? 229 SER A CA  1 
ATOM 3062 C C   . SER B 2 125 ? 150.528 86.534  140.188 1.00 125.85 ? 229 SER A C   1 
ATOM 3063 O O   . SER B 2 125 ? 150.930 85.508  140.747 1.00 127.19 ? 229 SER A O   1 
ATOM 3064 C CB  . SER B 2 125 ? 152.610 87.755  139.561 1.00 127.10 ? 229 SER A CB  1 
ATOM 3065 O OG  . SER B 2 125 ? 152.318 88.743  140.533 1.00 128.48 ? 229 SER A OG  1 
ATOM 3066 N N   . HIS B 2 131 ? 140.516 86.281  140.266 1.00 113.96 ? 245 HIS A N   1 
ATOM 3067 C CA  . HIS B 2 131 ? 139.061 86.208  140.366 1.00 113.59 ? 245 HIS A CA  1 
ATOM 3068 C C   . HIS B 2 131 ? 138.498 87.448  141.045 1.00 113.87 ? 245 HIS A C   1 
ATOM 3069 O O   . HIS B 2 131 ? 137.474 87.991  140.614 1.00 113.56 ? 245 HIS A O   1 
ATOM 3070 C CB  . HIS B 2 131 ? 138.638 84.950  141.123 1.00 114.10 ? 245 HIS A CB  1 
ATOM 3071 C CG  . HIS B 2 131 ? 138.247 83.813  140.234 1.00 115.50 ? 245 HIS A CG  1 
ATOM 3072 N ND1 . HIS B 2 131 ? 139.115 82.799  139.893 1.00 116.17 ? 245 HIS A ND1 1 
ATOM 3073 C CD2 . HIS B 2 131 ? 137.076 83.530  139.616 1.00 114.47 ? 245 HIS A CD2 1 
ATOM 3074 C CE1 . HIS B 2 131 ? 138.496 81.940  139.104 1.00 114.50 ? 245 HIS A CE1 1 
ATOM 3075 N NE2 . HIS B 2 131 ? 137.258 82.360  138.919 1.00 113.99 ? 245 HIS A NE2 1 
ATOM 3076 N N   . GLU B 2 132 ? 139.158 87.916  142.106 1.00 108.57 ? 246 GLU A N   1 
ATOM 3077 C CA  . GLU B 2 132 ? 138.721 89.148  142.752 1.00 108.00 ? 246 GLU A CA  1 
ATOM 3078 C C   . GLU B 2 132 ? 138.815 90.329  141.796 1.00 108.64 ? 246 GLU A C   1 
ATOM 3079 O O   . GLU B 2 132 ? 137.895 91.152  141.726 1.00 108.52 ? 246 GLU A O   1 
ATOM 3080 C CB  . GLU B 2 132 ? 139.549 89.405  144.010 1.00 106.13 ? 246 GLU A CB  1 
ATOM 3081 N N   . SER B 2 133 ? 139.915 90.421  141.043 1.00 97.76  ? 247 SER A N   1 
ATOM 3082 C CA  . SER B 2 133 ? 140.068 91.512  140.086 1.00 94.19  ? 247 SER A CA  1 
ATOM 3083 C C   . SER B 2 133 ? 138.974 91.466  139.029 1.00 94.13  ? 247 SER A C   1 
ATOM 3084 O O   . SER B 2 133 ? 138.418 92.505  138.656 1.00 95.89  ? 247 SER A O   1 
ATOM 3085 C CB  . SER B 2 133 ? 141.448 91.450  139.434 1.00 95.57  ? 247 SER A CB  1 
ATOM 3086 O OG  . SER B 2 133 ? 142.474 91.478  140.410 1.00 98.47  ? 247 SER A OG  1 
ATOM 3087 N N   . LEU B 2 134 ? 138.647 90.267  138.543 1.00 92.76  ? 248 LEU A N   1 
ATOM 3088 C CA  . LEU B 2 134 ? 137.537 90.127  137.607 1.00 93.57  ? 248 LEU A CA  1 
ATOM 3089 C C   . LEU B 2 134 ? 136.225 90.564  138.246 1.00 92.89  ? 248 LEU A C   1 
ATOM 3090 O O   . LEU B 2 134 ? 135.368 91.153  137.580 1.00 92.45  ? 248 LEU A O   1 
ATOM 3091 C CB  . LEU B 2 134 ? 137.443 88.682  137.119 1.00 91.56  ? 248 LEU A CB  1 
ATOM 3092 C CG  . LEU B 2 134 ? 137.873 88.418  135.675 1.00 89.92  ? 248 LEU A CG  1 
ATOM 3093 C CD1 . LEU B 2 134 ? 138.032 86.928  135.424 1.00 92.92  ? 248 LEU A CD1 1 
ATOM 3094 C CD2 . LEU B 2 134 ? 136.879 89.022  134.701 1.00 89.55  ? 248 LEU A CD2 1 
ATOM 3095 N N   . MET B 2 135 ? 136.053 90.286  139.540 1.00 98.14  ? 249 MET A N   1 
ATOM 3096 C CA  . MET B 2 135 ? 134.824 90.681  140.224 1.00 99.28  ? 249 MET A CA  1 
ATOM 3097 C C   . MET B 2 135 ? 134.694 92.199  140.304 1.00 98.43  ? 249 MET A C   1 
ATOM 3098 O O   . MET B 2 135 ? 133.634 92.756  139.989 1.00 98.46  ? 249 MET A O   1 
ATOM 3099 C CB  . MET B 2 135 ? 134.776 90.060  141.620 1.00 98.70  ? 249 MET A CB  1 
ATOM 3100 C CG  . MET B 2 135 ? 133.383 90.023  142.236 1.00 101.04 ? 249 MET A CG  1 
ATOM 3101 S SD  . MET B 2 135 ? 132.157 89.109  141.273 1.00 105.44 ? 249 MET A SD  1 
ATOM 3102 C CE  . MET B 2 135 ? 133.079 87.648  140.793 1.00 96.57  ? 249 MET A CE  1 
ATOM 3103 N N   . LEU B 2 136 ? 135.784 92.869  140.693 1.00 88.87  ? 250 LEU A N   1 
ATOM 3104 C CA  . LEU B 2 136 ? 135.772 94.356  140.719 1.00 88.32  ? 250 LEU A CA  1 
ATOM 3105 C C   . LEU B 2 136 ? 135.478 94.858  139.314 1.00 85.33  ? 250 LEU A C   1 
ATOM 3106 O O   . LEU B 2 136 ? 134.608 95.711  139.149 1.00 86.90  ? 250 LEU A O   1 
ATOM 3107 C CB  . LEU B 2 136 ? 137.139 94.877  141.147 1.00 86.94  ? 250 LEU A CB  1 
ATOM 3108 C CG  . LEU B 2 136 ? 137.300 95.193  142.629 1.00 89.24  ? 250 LEU A CG  1 
ATOM 3109 C CD1 . LEU B 2 136 ? 138.098 94.103  143.323 1.00 89.63  ? 250 LEU A CD1 1 
ATOM 3110 C CD2 . LEU B 2 136 ? 137.972 96.543  142.815 1.00 88.17  ? 250 LEU A CD2 1 
ATOM 3111 N N   . PHE B 2 137 ? 136.164 94.298  138.336 1.00 73.55  ? 251 PHE A N   1 
ATOM 3112 C CA  . PHE B 2 137 ? 135.996 94.786  136.970 1.00 72.05  ? 251 PHE A CA  1 
ATOM 3113 C C   . PHE B 2 137 ? 134.549 94.656  136.513 1.00 77.10  ? 251 PHE A C   1 
ATOM 3114 O O   . PHE B 2 137 ? 133.999 95.575  135.895 1.00 81.51  ? 251 PHE A O   1 
ATOM 3115 C CB  . PHE B 2 137 ? 136.930 94.042  136.016 1.00 70.53  ? 251 PHE A CB  1 
ATOM 3116 C CG  . PHE B 2 137 ? 136.987 94.641  134.639 1.00 70.27  ? 251 PHE A CG  1 
ATOM 3117 C CD1 . PHE B 2 137 ? 136.046 94.307  133.680 1.00 77.00  ? 251 PHE A CD1 1 
ATOM 3118 C CD2 . PHE B 2 137 ? 137.975 95.549  134.308 1.00 71.13  ? 251 PHE A CD2 1 
ATOM 3119 C CE1 . PHE B 2 137 ? 136.094 94.862  132.420 1.00 70.42  ? 251 PHE A CE1 1 
ATOM 3120 C CE2 . PHE B 2 137 ? 138.028 96.106  133.047 1.00 73.95  ? 251 PHE A CE2 1 
ATOM 3121 C CZ  . PHE B 2 137 ? 137.086 95.761  132.103 1.00 70.89  ? 251 PHE A CZ  1 
ATOM 3122 N N   . ASP B 2 138 ? 133.916 93.518  136.806 1.00 87.15  ? 252 ASP A N   1 
ATOM 3123 C CA  . ASP B 2 138 ? 132.514 93.338  136.449 1.00 88.21  ? 252 ASP A CA  1 
ATOM 3124 C C   . ASP B 2 138 ? 131.636 94.346  137.179 1.00 88.18  ? 252 ASP A C   1 
ATOM 3125 O O   . ASP B 2 138 ? 130.709 94.915  136.591 1.00 90.21  ? 252 ASP A O   1 
ATOM 3126 C CB  . ASP B 2 138 ? 132.074 91.908  136.765 1.00 88.68  ? 252 ASP A CB  1 
ATOM 3127 C CG  . ASP B 2 138 ? 130.810 91.503  136.025 1.00 90.22  ? 252 ASP A CG  1 
ATOM 3128 O OD1 . ASP B 2 138 ? 130.038 92.392  135.611 1.00 88.47  ? 252 ASP A OD1 1 
ATOM 3129 O OD2 . ASP B 2 138 ? 130.586 90.285  135.859 1.00 91.82  ? 252 ASP A OD2 1 
ATOM 3130 N N   . SER B 2 139 ? 131.918 94.582  138.462 1.00 89.14  ? 253 SER A N   1 
ATOM 3131 C CA  . SER B 2 139 ? 131.120 95.532  139.230 1.00 90.92  ? 253 SER A CA  1 
ATOM 3132 C C   . SER B 2 139 ? 131.271 96.952  138.695 1.00 92.01  ? 253 SER A C   1 
ATOM 3133 O O   . SER B 2 139 ? 130.291 97.703  138.625 1.00 92.72  ? 253 SER A O   1 
ATOM 3134 C CB  . SER B 2 139 ? 131.513 95.470  140.705 1.00 92.19  ? 253 SER A CB  1 
ATOM 3135 O OG  . SER B 2 139 ? 131.793 94.139  141.100 1.00 95.73  ? 253 SER A OG  1 
ATOM 3136 N N   . ILE B 2 140 ? 132.489 97.339  138.310 1.00 91.47  ? 254 ILE A N   1 
ATOM 3137 C CA  . ILE B 2 140 ? 132.735 98.729  137.942 1.00 90.18  ? 254 ILE A CA  1 
ATOM 3138 C C   . ILE B 2 140 ? 132.319 98.988  136.495 1.00 86.33  ? 254 ILE A C   1 
ATOM 3139 O O   . ILE B 2 140 ? 131.939 100.112 136.146 1.00 85.32  ? 254 ILE A O   1 
ATOM 3140 C CB  . ILE B 2 140 ? 134.216 99.084  138.174 1.00 84.54  ? 254 ILE A CB  1 
ATOM 3141 C CG1 . ILE B 2 140 ? 134.464 100.577 137.981 1.00 85.25  ? 254 ILE A CG1 1 
ATOM 3142 C CG2 . ILE B 2 140 ? 135.112 98.331  137.211 1.00 85.49  ? 254 ILE A CG2 1 
ATOM 3143 C CD1 . ILE B 2 140 ? 133.402 101.445 138.593 1.00 85.04  ? 254 ILE A CD1 1 
ATOM 3144 N N   . CYS B 2 141 ? 132.367 97.967  135.636 1.00 85.25  ? 255 CYS A N   1 
ATOM 3145 C CA  . CYS B 2 141 ? 132.041 98.171  134.229 1.00 86.27  ? 255 CYS A CA  1 
ATOM 3146 C C   . CYS B 2 141 ? 130.541 98.329  134.020 1.00 89.56  ? 255 CYS A C   1 
ATOM 3147 O O   . CYS B 2 141 ? 130.106 99.128  133.182 1.00 93.14  ? 255 CYS A O   1 
ATOM 3148 C CB  . CYS B 2 141 ? 132.579 97.012  133.392 1.00 87.28  ? 255 CYS A CB  1 
ATOM 3149 S SG  . CYS B 2 141 ? 132.413 97.248  131.610 1.00 93.71  ? 255 CYS A SG  1 
ATOM 3150 N N   . ASN B 2 142 ? 129.735 97.579  134.767 1.00 91.74  ? 256 ASN A N   1 
ATOM 3151 C CA  . ASN B 2 142 ? 128.287 97.594  134.612 1.00 91.70  ? 256 ASN A CA  1 
ATOM 3152 C C   . ASN B 2 142 ? 127.595 98.521  135.602 1.00 92.08  ? 256 ASN A C   1 
ATOM 3153 O O   . ASN B 2 142 ? 126.369 98.461  135.737 1.00 91.40  ? 256 ASN A O   1 
ATOM 3154 C CB  . ASN B 2 142 ? 127.727 96.176  134.745 1.00 94.38  ? 256 ASN A CB  1 
ATOM 3155 C CG  . ASN B 2 142 ? 128.485 95.169  133.902 1.00 94.11  ? 256 ASN A CG  1 
ATOM 3156 O OD1 . ASN B 2 142 ? 128.157 94.947  132.737 1.00 92.35  ? 256 ASN A OD1 1 
ATOM 3157 N ND2 . ASN B 2 142 ? 129.504 94.552  134.489 1.00 92.36  ? 256 ASN A ND2 1 
ATOM 3158 N N   . ASN B 2 143 ? 128.347 99.367  136.302 1.00 95.67  ? 257 ASN A N   1 
ATOM 3159 C CA  . ASN B 2 143 ? 127.738 100.342 137.192 1.00 94.06  ? 257 ASN A CA  1 
ATOM 3160 C C   . ASN B 2 143 ? 126.936 101.359 136.387 1.00 94.03  ? 257 ASN A C   1 
ATOM 3161 O O   . ASN B 2 143 ? 127.304 101.730 135.270 1.00 93.41  ? 257 ASN A O   1 
ATOM 3162 C CB  . ASN B 2 143 ? 128.808 101.051 138.022 1.00 93.50  ? 257 ASN A CB  1 
ATOM 3163 C CG  . ASN B 2 143 ? 128.250 101.666 139.289 1.00 97.58  ? 257 ASN A CG  1 
ATOM 3164 O OD1 . ASN B 2 143 ? 127.111 102.132 139.318 1.00 98.06  ? 257 ASN A OD1 1 
ATOM 3165 N ND2 . ASN B 2 143 ? 129.052 101.671 140.347 1.00 99.02  ? 257 ASN A ND2 1 
ATOM 3166 N N   . LYS B 2 144 ? 125.823 101.811 136.969 1.00 96.42  ? 258 LYS A N   1 
ATOM 3167 C CA  . LYS B 2 144 ? 124.919 102.694 136.244 1.00 96.56  ? 258 LYS A CA  1 
ATOM 3168 C C   . LYS B 2 144 ? 125.513 104.076 136.007 1.00 98.68  ? 258 LYS A C   1 
ATOM 3169 O O   . LYS B 2 144 ? 125.096 104.761 135.068 1.00 101.24 ? 258 LYS A O   1 
ATOM 3170 C CB  . LYS B 2 144 ? 123.588 102.816 136.991 1.00 98.06  ? 258 LYS A CB  1 
ATOM 3171 C CG  . LYS B 2 144 ? 123.622 103.744 138.193 1.00 97.08  ? 258 LYS A CG  1 
ATOM 3172 C CD  . LYS B 2 144 ? 122.287 103.754 138.919 1.00 96.08  ? 258 LYS A CD  1 
ATOM 3173 C CE  . LYS B 2 144 ? 122.257 102.722 140.036 1.00 98.70  ? 258 LYS A CE  1 
ATOM 3174 N NZ  . LYS B 2 144 ? 123.402 102.884 140.974 1.00 98.47  ? 258 LYS A NZ  1 
ATOM 3175 N N   . PHE B 2 145 ? 126.472 104.502 136.830 1.00 88.45  ? 259 PHE A N   1 
ATOM 3176 C CA  . PHE B 2 145 ? 127.093 105.806 136.631 1.00 90.63  ? 259 PHE A CA  1 
ATOM 3177 C C   . PHE B 2 145 ? 128.112 105.794 135.497 1.00 90.62  ? 259 PHE A C   1 
ATOM 3178 O O   . PHE B 2 145 ? 128.277 106.806 134.808 1.00 85.62  ? 259 PHE A O   1 
ATOM 3179 C CB  . PHE B 2 145 ? 127.757 106.279 137.925 1.00 86.10  ? 259 PHE A CB  1 
ATOM 3180 C CG  . PHE B 2 145 ? 126.825 106.335 139.103 1.00 89.09  ? 259 PHE A CG  1 
ATOM 3181 C CD1 . PHE B 2 145 ? 125.654 107.071 139.045 1.00 87.73  ? 259 PHE A CD1 1 
ATOM 3182 C CD2 . PHE B 2 145 ? 127.124 105.657 140.271 1.00 92.72  ? 259 PHE A CD2 1 
ATOM 3183 C CE1 . PHE B 2 145 ? 124.798 107.127 140.127 1.00 88.72  ? 259 PHE A CE1 1 
ATOM 3184 C CE2 . PHE B 2 145 ? 126.271 105.709 141.358 1.00 91.47  ? 259 PHE A CE2 1 
ATOM 3185 C CZ  . PHE B 2 145 ? 125.107 106.445 141.285 1.00 90.08  ? 259 PHE A CZ  1 
ATOM 3186 N N   . PHE B 2 146 ? 128.793 104.671 135.284 1.00 80.07  ? 260 PHE A N   1 
ATOM 3187 C CA  . PHE B 2 146 ? 129.905 104.580 134.344 1.00 75.71  ? 260 PHE A CA  1 
ATOM 3188 C C   . PHE B 2 146 ? 129.550 103.739 133.121 1.00 76.11  ? 260 PHE A C   1 
ATOM 3189 O O   . PHE B 2 146 ? 130.371 102.974 132.612 1.00 71.01  ? 260 PHE A O   1 
ATOM 3190 C CB  . PHE B 2 146 ? 131.140 104.017 135.038 1.00 75.65  ? 260 PHE A CB  1 
ATOM 3191 C CG  . PHE B 2 146 ? 131.603 104.844 136.199 1.00 77.23  ? 260 PHE A CG  1 
ATOM 3192 C CD1 . PHE B 2 146 ? 131.558 106.224 136.145 1.00 78.75  ? 260 PHE A CD1 1 
ATOM 3193 C CD2 . PHE B 2 146 ? 132.066 104.242 137.350 1.00 74.90  ? 260 PHE A CD2 1 
ATOM 3194 C CE1 . PHE B 2 146 ? 131.978 106.984 137.215 1.00 74.50  ? 260 PHE A CE1 1 
ATOM 3195 C CE2 . PHE B 2 146 ? 132.489 104.995 138.424 1.00 74.44  ? 260 PHE A CE2 1 
ATOM 3196 C CZ  . PHE B 2 146 ? 132.444 106.369 138.356 1.00 75.80  ? 260 PHE A CZ  1 
ATOM 3197 N N   . ILE B 2 147 ? 128.312 103.873 132.640 1.00 88.86  ? 261 ILE A N   1 
ATOM 3198 C CA  . ILE B 2 147 ? 127.893 103.155 131.443 1.00 89.40  ? 261 ILE A CA  1 
ATOM 3199 C C   . ILE B 2 147 ? 128.581 103.700 130.197 1.00 89.34  ? 261 ILE A C   1 
ATOM 3200 O O   . ILE B 2 147 ? 128.803 102.954 129.235 1.00 89.47  ? 261 ILE A O   1 
ATOM 3201 C CB  . ILE B 2 147 ? 126.356 103.215 131.322 1.00 90.90  ? 261 ILE A CB  1 
ATOM 3202 C CG1 . ILE B 2 147 ? 125.710 102.323 132.383 1.00 89.20  ? 261 ILE A CG1 1 
ATOM 3203 C CG2 . ILE B 2 147 ? 125.886 102.792 129.938 1.00 88.33  ? 261 ILE A CG2 1 
ATOM 3204 C CD1 . ILE B 2 147 ? 126.184 100.887 132.340 1.00 88.14  ? 261 ILE A CD1 1 
ATOM 3205 N N   . ASP B 2 148 ? 128.970 104.975 130.204 1.00 75.32  ? 262 ASP A N   1 
ATOM 3206 C CA  . ASP B 2 148 ? 129.572 105.606 129.040 1.00 70.80  ? 262 ASP A CA  1 
ATOM 3207 C C   . ASP B 2 148 ? 131.033 105.981 129.242 1.00 70.42  ? 262 ASP A C   1 
ATOM 3208 O O   . ASP B 2 148 ? 131.644 106.538 128.322 1.00 69.52  ? 262 ASP A O   1 
ATOM 3209 C CB  . ASP B 2 148 ? 128.781 106.862 128.651 1.00 71.99  ? 262 ASP A CB  1 
ATOM 3210 C CG  . ASP B 2 148 ? 127.786 106.602 127.542 1.00 74.87  ? 262 ASP A CG  1 
ATOM 3211 O OD1 . ASP B 2 148 ? 127.597 105.423 127.180 1.00 74.16  ? 262 ASP A OD1 1 
ATOM 3212 O OD2 . ASP B 2 148 ? 127.194 107.577 127.032 1.00 73.35  ? 262 ASP A OD2 1 
ATOM 3213 N N   . THR B 2 149 ? 131.612 105.695 130.405 1.00 59.48  ? 263 THR A N   1 
ATOM 3214 C CA  . THR B 2 149 ? 132.997 106.048 130.689 1.00 56.53  ? 263 THR A CA  1 
ATOM 3215 C C   . THR B 2 149 ? 133.907 104.904 130.256 1.00 49.81  ? 263 THR A C   1 
ATOM 3216 O O   . THR B 2 149 ? 133.753 103.771 130.721 1.00 61.81  ? 263 THR A O   1 
ATOM 3217 C CB  . THR B 2 149 ? 133.184 106.355 132.175 1.00 52.37  ? 263 THR A CB  1 
ATOM 3218 O OG1 . THR B 2 149 ? 132.687 107.669 132.458 1.00 49.42  ? 263 THR A OG1 1 
ATOM 3219 C CG2 . THR B 2 149 ? 134.654 106.292 132.549 1.00 49.04  ? 263 THR A CG2 1 
ATOM 3220 N N   . SER B 2 150 ? 134.847 105.203 129.364 1.00 35.73  ? 264 SER A N   1 
ATOM 3221 C CA  . SER B 2 150 ? 135.755 104.188 128.858 1.00 33.95  ? 264 SER A CA  1 
ATOM 3222 C C   . SER B 2 150 ? 136.757 103.776 129.932 1.00 39.81  ? 264 SER A C   1 
ATOM 3223 O O   . SER B 2 150 ? 137.023 104.507 130.889 1.00 50.93  ? 264 SER A O   1 
ATOM 3224 C CB  . SER B 2 150 ? 136.488 104.699 127.620 1.00 51.25  ? 264 SER A CB  1 
ATOM 3225 O OG  . SER B 2 150 ? 135.568 105.155 126.645 1.00 62.96  ? 264 SER A OG  1 
ATOM 3226 N N   . ILE B 2 151 ? 137.317 102.582 129.761 1.00 27.19  ? 265 ILE A N   1 
ATOM 3227 C CA  . ILE B 2 151 ? 138.221 101.979 130.732 1.00 18.04  ? 265 ILE A CA  1 
ATOM 3228 C C   . ILE B 2 151 ? 139.568 101.744 130.067 1.00 24.60  ? 265 ILE A C   1 
ATOM 3229 O O   . ILE B 2 151 ? 139.634 101.178 128.970 1.00 48.78  ? 265 ILE A O   1 
ATOM 3230 C CB  . ILE B 2 151 ? 137.654 100.659 131.285 1.00 7.41   ? 265 ILE A CB  1 
ATOM 3231 C CG1 . ILE B 2 151 ? 136.338 100.910 132.020 1.00 23.27  ? 265 ILE A CG1 1 
ATOM 3232 C CG2 . ILE B 2 151 ? 138.659 99.986  132.200 1.00 26.85  ? 265 ILE A CG2 1 
ATOM 3233 C CD1 . ILE B 2 151 ? 135.588 99.649  132.363 1.00 35.25  ? 265 ILE A CD1 1 
ATOM 3234 N N   . ILE B 2 152 ? 140.636 102.180 130.726 1.00 35.94  ? 266 ILE A N   1 
ATOM 3235 C CA  . ILE B 2 152 ? 141.999 101.874 130.310 1.00 41.29  ? 266 ILE A CA  1 
ATOM 3236 C C   . ILE B 2 152 ? 142.506 100.755 131.207 1.00 45.37  ? 266 ILE A C   1 
ATOM 3237 O O   . ILE B 2 152 ? 142.637 100.936 132.423 1.00 53.79  ? 266 ILE A O   1 
ATOM 3238 C CB  . ILE B 2 152 ? 142.908 103.110 130.395 1.00 38.35  ? 266 ILE A CB  1 
ATOM 3239 C CG1 . ILE B 2 152 ? 142.250 104.306 129.710 1.00 35.90  ? 266 ILE A CG1 1 
ATOM 3240 C CG2 . ILE B 2 152 ? 144.259 102.823 129.760 1.00 37.96  ? 266 ILE A CG2 1 
ATOM 3241 C CD1 . ILE B 2 152 ? 142.792 105.637 130.173 1.00 40.98  ? 266 ILE A CD1 1 
ATOM 3242 N N   . LEU B 2 153 ? 142.786 99.599  130.618 1.00 40.59  ? 267 LEU A N   1 
ATOM 3243 C CA  . LEU B 2 153 ? 143.168 98.413  131.370 1.00 41.10  ? 267 LEU A CA  1 
ATOM 3244 C C   . LEU B 2 153 ? 144.672 98.205  131.265 1.00 41.35  ? 267 LEU A C   1 
ATOM 3245 O O   . LEU B 2 153 ? 145.223 98.164  130.161 1.00 52.36  ? 267 LEU A O   1 
ATOM 3246 C CB  . LEU B 2 153 ? 142.420 97.181  130.856 1.00 45.28  ? 267 LEU A CB  1 
ATOM 3247 C CG  . LEU B 2 153 ? 142.746 95.835  131.505 1.00 44.67  ? 267 LEU A CG  1 
ATOM 3248 C CD1 . LEU B 2 153 ? 142.049 95.711  132.843 1.00 46.14  ? 267 LEU A CD1 1 
ATOM 3249 C CD2 . LEU B 2 153 ? 142.347 94.692  130.591 1.00 45.45  ? 267 LEU A CD2 1 
ATOM 3250 N N   . PHE B 2 154 ? 145.330 98.080  132.414 1.00 50.82  ? 268 PHE A N   1 
ATOM 3251 C CA  . PHE B 2 154 ? 146.769 97.864  132.487 1.00 53.77  ? 268 PHE A CA  1 
ATOM 3252 C C   . PHE B 2 154 ? 147.026 96.488  133.084 1.00 55.22  ? 268 PHE A C   1 
ATOM 3253 O O   . PHE B 2 154 ? 146.539 96.183  134.178 1.00 61.19  ? 268 PHE A O   1 
ATOM 3254 C CB  . PHE B 2 154 ? 147.444 98.946  133.329 1.00 62.21  ? 268 PHE A CB  1 
ATOM 3255 C CG  . PHE B 2 154 ? 147.773 100.196 132.565 1.00 60.07  ? 268 PHE A CG  1 
ATOM 3256 C CD1 . PHE B 2 154 ? 148.527 100.139 131.407 1.00 57.46  ? 268 PHE A CD1 1 
ATOM 3257 C CD2 . PHE B 2 154 ? 147.326 101.429 133.006 1.00 54.92  ? 268 PHE A CD2 1 
ATOM 3258 C CE1 . PHE B 2 154 ? 148.828 101.288 130.704 1.00 60.71  ? 268 PHE A CE1 1 
ATOM 3259 C CE2 . PHE B 2 154 ? 147.624 102.580 132.307 1.00 54.51  ? 268 PHE A CE2 1 
ATOM 3260 C CZ  . PHE B 2 154 ? 148.375 102.509 131.155 1.00 58.05  ? 268 PHE A CZ  1 
ATOM 3261 N N   . LEU B 2 155 ? 147.788 95.666  132.371 1.00 61.89  ? 269 LEU A N   1 
ATOM 3262 C CA  . LEU B 2 155 ? 148.183 94.340  132.839 1.00 66.04  ? 269 LEU A CA  1 
ATOM 3263 C C   . LEU B 2 155 ? 149.650 94.423  133.248 1.00 74.21  ? 269 LEU A C   1 
ATOM 3264 O O   . LEU B 2 155 ? 150.541 94.458  132.396 1.00 81.36  ? 269 LEU A O   1 
ATOM 3265 C CB  . LEU B 2 155 ? 147.952 93.288  131.759 1.00 67.66  ? 269 LEU A CB  1 
ATOM 3266 C CG  . LEU B 2 155 ? 146.510 93.137  131.268 1.00 71.95  ? 269 LEU A CG  1 
ATOM 3267 C CD1 . LEU B 2 155 ? 146.403 92.018  130.251 1.00 72.47  ? 269 LEU A CD1 1 
ATOM 3268 C CD2 . LEU B 2 155 ? 145.564 92.892  132.429 1.00 72.02  ? 269 LEU A CD2 1 
ATOM 3269 N N   . ASN B 2 156 ? 149.894 94.453  134.553 1.00 85.73  ? 270 ASN A N   1 
ATOM 3270 C CA  . ASN B 2 156 ? 151.229 94.671  135.087 1.00 84.55  ? 270 ASN A CA  1 
ATOM 3271 C C   . ASN B 2 156 ? 151.995 93.359  135.219 1.00 87.66  ? 270 ASN A C   1 
ATOM 3272 O O   . ASN B 2 156 ? 151.427 92.266  135.159 1.00 87.73  ? 270 ASN A O   1 
ATOM 3273 C CB  . ASN B 2 156 ? 151.155 95.361  136.449 1.00 83.29  ? 270 ASN A CB  1 
ATOM 3274 C CG  . ASN B 2 156 ? 150.459 96.704  136.387 1.00 83.04  ? 270 ASN A CG  1 
ATOM 3275 O OD1 . ASN B 2 156 ? 149.405 96.898  136.991 1.00 83.83  ? 270 ASN A OD1 1 
ATOM 3276 N ND2 . ASN B 2 156 ? 151.049 97.643  135.658 1.00 85.34  ? 270 ASN A ND2 1 
ATOM 3277 N N   . LYS B 2 157 ? 153.310 93.491  135.401 1.00 107.06 ? 271 LYS A N   1 
ATOM 3278 C CA  . LYS B 2 157 ? 154.197 92.379  135.741 1.00 108.53 ? 271 LYS A CA  1 
ATOM 3279 C C   . LYS B 2 157 ? 154.156 91.278  134.678 1.00 108.79 ? 271 LYS A C   1 
ATOM 3280 O O   . LYS B 2 157 ? 153.733 90.147  134.926 1.00 109.51 ? 271 LYS A O   1 
ATOM 3281 C CB  . LYS B 2 157 ? 153.855 91.827  137.129 1.00 108.68 ? 271 LYS A CB  1 
ATOM 3282 C CG  . LYS B 2 157 ? 154.054 92.832  138.252 1.00 108.43 ? 271 LYS A CG  1 
ATOM 3283 C CD  . LYS B 2 157 ? 153.549 92.295  139.580 1.00 109.32 ? 271 LYS A CD  1 
ATOM 3284 C CE  . LYS B 2 157 ? 153.324 93.420  140.576 1.00 108.71 ? 271 LYS A CE  1 
ATOM 3285 N NZ  . LYS B 2 157 ? 152.385 93.024  141.661 1.00 108.52 ? 271 LYS A NZ  1 
ATOM 3286 N N   . LYS B 2 158 ? 154.603 91.636  133.472 1.00 112.49 ? 272 LYS A N   1 
ATOM 3287 C CA  . LYS B 2 158 ? 154.731 90.644  132.409 1.00 114.23 ? 272 LYS A CA  1 
ATOM 3288 C C   . LYS B 2 158 ? 155.781 89.597  132.761 1.00 117.33 ? 272 LYS A C   1 
ATOM 3289 O O   . LYS B 2 158 ? 155.566 88.395  132.570 1.00 116.26 ? 272 LYS A O   1 
ATOM 3290 C CB  . LYS B 2 158 ? 155.090 91.323  131.088 1.00 115.02 ? 272 LYS A CB  1 
ATOM 3291 C CG  . LYS B 2 158 ? 154.110 92.378  130.621 1.00 113.59 ? 272 LYS A CG  1 
ATOM 3292 C CD  . LYS B 2 158 ? 154.452 92.825  129.208 1.00 115.89 ? 272 LYS A CD  1 
ATOM 3293 C CE  . LYS B 2 158 ? 155.811 93.504  129.146 1.00 115.46 ? 272 LYS A CE  1 
ATOM 3294 N NZ  . LYS B 2 158 ? 155.807 94.826  129.826 1.00 111.26 ? 272 LYS A NZ  1 
ATOM 3295 N N   . ASP B 2 159 ? 156.934 90.043  133.268 1.00 127.76 ? 273 ASP A N   1 
ATOM 3296 C CA  . ASP B 2 159 ? 158.031 89.121  133.551 1.00 128.12 ? 273 ASP A CA  1 
ATOM 3297 C C   . ASP B 2 159 ? 157.646 88.144  134.655 1.00 127.37 ? 273 ASP A C   1 
ATOM 3298 O O   . ASP B 2 159 ? 157.935 86.945  134.561 1.00 126.95 ? 273 ASP A O   1 
ATOM 3299 C CB  . ASP B 2 159 ? 159.289 89.925  133.910 1.00 128.08 ? 273 ASP A CB  1 
ATOM 3300 C CG  . ASP B 2 159 ? 160.470 89.057  134.360 1.00 129.28 ? 273 ASP A CG  1 
ATOM 3301 O OD1 . ASP B 2 159 ? 160.318 88.145  135.198 1.00 130.03 ? 273 ASP A OD1 1 
ATOM 3302 O OD2 . ASP B 2 159 ? 161.585 89.301  133.851 1.00 128.56 ? 273 ASP A OD2 1 
ATOM 3303 N N   . LEU B 2 160 ? 156.994 88.639  135.710 1.00 126.65 ? 274 LEU A N   1 
ATOM 3304 C CA  . LEU B 2 160 ? 156.581 87.760  136.799 1.00 128.34 ? 274 LEU A CA  1 
ATOM 3305 C C   . LEU B 2 160 ? 155.578 86.720  136.318 1.00 127.65 ? 274 LEU A C   1 
ATOM 3306 O O   . LEU B 2 160 ? 155.670 85.544  136.687 1.00 127.89 ? 274 LEU A O   1 
ATOM 3307 C CB  . LEU B 2 160 ? 155.996 88.584  137.947 1.00 128.37 ? 274 LEU A CB  1 
ATOM 3308 C CG  . LEU B 2 160 ? 156.948 89.559  138.643 1.00 127.51 ? 274 LEU A CG  1 
ATOM 3309 C CD1 . LEU B 2 160 ? 156.401 89.962  140.003 1.00 126.13 ? 274 LEU A CD1 1 
ATOM 3310 C CD2 . LEU B 2 160 ? 158.337 88.957  138.781 1.00 127.87 ? 274 LEU A CD2 1 
ATOM 3311 N N   . PHE B 2 161 ? 154.616 87.133  135.491 1.00 121.58 ? 275 PHE A N   1 
ATOM 3312 C CA  . PHE B 2 161 ? 153.645 86.186  134.952 1.00 121.88 ? 275 PHE A CA  1 
ATOM 3313 C C   . PHE B 2 161 ? 154.318 85.148  134.063 1.00 123.33 ? 275 PHE A C   1 
ATOM 3314 O O   . PHE B 2 161 ? 154.000 83.954  134.136 1.00 122.72 ? 275 PHE A O   1 
ATOM 3315 C CB  . PHE B 2 161 ? 152.561 86.936  134.179 1.00 121.70 ? 275 PHE A CB  1 
ATOM 3316 C CG  . PHE B 2 161 ? 151.592 86.039  133.465 1.00 121.71 ? 275 PHE A CG  1 
ATOM 3317 C CD1 . PHE B 2 161 ? 150.827 85.124  134.167 1.00 121.79 ? 275 PHE A CD1 1 
ATOM 3318 C CD2 . PHE B 2 161 ? 151.446 86.113  132.089 1.00 119.98 ? 275 PHE A CD2 1 
ATOM 3319 C CE1 . PHE B 2 161 ? 149.934 84.300  133.511 1.00 122.01 ? 275 PHE A CE1 1 
ATOM 3320 C CE2 . PHE B 2 161 ? 150.554 85.292  131.428 1.00 118.92 ? 275 PHE A CE2 1 
ATOM 3321 C CZ  . PHE B 2 161 ? 149.798 84.384  132.139 1.00 121.50 ? 275 PHE A CZ  1 
ATOM 3322 N N   . GLY B 2 162 ? 155.249 85.586  133.211 1.00 125.15 ? 276 GLY A N   1 
ATOM 3323 C CA  . GLY B 2 162 ? 155.951 84.656  132.344 1.00 125.13 ? 276 GLY A CA  1 
ATOM 3324 C C   . GLY B 2 162 ? 156.823 83.675  133.101 1.00 126.00 ? 276 GLY A C   1 
ATOM 3325 O O   . GLY B 2 162 ? 156.995 82.531  132.670 1.00 124.71 ? 276 GLY A O   1 
ATOM 3326 N N   . GLU B 2 163 ? 157.400 84.107  134.222 1.00 125.77 ? 277 GLU A N   1 
ATOM 3327 C CA  . GLU B 2 163 ? 158.187 83.194  135.041 1.00 125.33 ? 277 GLU A CA  1 
ATOM 3328 C C   . GLU B 2 163 ? 157.303 82.253  135.851 1.00 125.47 ? 277 GLU A C   1 
ATOM 3329 O O   . GLU B 2 163 ? 157.681 81.098  136.078 1.00 125.31 ? 277 GLU A O   1 
ATOM 3330 C CB  . GLU B 2 163 ? 159.109 83.984  135.972 1.00 124.43 ? 277 GLU A CB  1 
ATOM 3331 C CG  . GLU B 2 163 ? 160.171 83.146  136.672 1.00 124.48 ? 277 GLU A CG  1 
ATOM 3332 C CD  . GLU B 2 163 ? 161.255 82.657  135.728 1.00 125.71 ? 277 GLU A CD  1 
ATOM 3333 O OE1 . GLU B 2 163 ? 160.997 81.713  134.952 1.00 125.99 ? 277 GLU A OE1 1 
ATOM 3334 O OE2 . GLU B 2 163 ? 162.369 83.221  135.761 1.00 125.92 ? 277 GLU A OE2 1 
ATOM 3335 N N   . LYS B 2 164 ? 156.133 82.722  136.289 1.00 128.10 ? 278 LYS A N   1 
ATOM 3336 C CA  . LYS B 2 164 ? 155.246 81.896  137.100 1.00 128.88 ? 278 LYS A CA  1 
ATOM 3337 C C   . LYS B 2 164 ? 154.492 80.863  136.273 1.00 128.05 ? 278 LYS A C   1 
ATOM 3338 O O   . LYS B 2 164 ? 154.190 79.777  136.781 1.00 128.24 ? 278 LYS A O   1 
ATOM 3339 C CB  . LYS B 2 164 ? 154.254 82.779  137.858 1.00 128.06 ? 278 LYS A CB  1 
ATOM 3340 N N   . ILE B 2 165 ? 154.171 81.177  135.015 1.00 124.93 ? 279 ILE A N   1 
ATOM 3341 C CA  . ILE B 2 165 ? 153.380 80.249  134.213 1.00 125.89 ? 279 ILE A CA  1 
ATOM 3342 C C   . ILE B 2 165 ? 154.153 78.961  133.949 1.00 126.34 ? 279 ILE A C   1 
ATOM 3343 O O   . ILE B 2 165 ? 153.561 77.875  133.897 1.00 125.45 ? 279 ILE A O   1 
ATOM 3344 C CB  . ILE B 2 165 ? 152.921 80.922  132.904 1.00 124.28 ? 279 ILE A CB  1 
ATOM 3345 C CG1 . ILE B 2 165 ? 152.087 79.956  132.063 1.00 124.65 ? 279 ILE A CG1 1 
ATOM 3346 C CG2 . ILE B 2 165 ? 154.108 81.423  132.101 1.00 124.63 ? 279 ILE A CG2 1 
ATOM 3347 C CD1 . ILE B 2 165 ? 151.313 80.631  130.960 1.00 125.30 ? 279 ILE A CD1 1 
ATOM 3348 N N   . LYS B 2 166 ? 155.474 79.050  133.781 1.00 126.44 ? 280 LYS A N   1 
ATOM 3349 C CA  . LYS B 2 166 ? 156.274 77.845  133.585 1.00 126.44 ? 280 LYS A CA  1 
ATOM 3350 C C   . LYS B 2 166 ? 156.235 76.950  134.818 1.00 125.44 ? 280 LYS A C   1 
ATOM 3351 O O   . LYS B 2 166 ? 156.118 75.725  134.702 1.00 124.80 ? 280 LYS A O   1 
ATOM 3352 C CB  . LYS B 2 166 ? 157.715 78.221  133.239 1.00 125.93 ? 280 LYS A CB  1 
ATOM 3353 C CG  . LYS B 2 166 ? 157.864 79.033  131.959 1.00 124.89 ? 280 LYS A CG  1 
ATOM 3354 C CD  . LYS B 2 166 ? 157.693 78.165  130.720 1.00 124.08 ? 280 LYS A CD  1 
ATOM 3355 C CE  . LYS B 2 166 ? 156.351 78.407  130.047 1.00 122.75 ? 280 LYS A CE  1 
ATOM 3356 N NZ  . LYS B 2 166 ? 156.208 77.618  128.793 1.00 124.60 ? 280 LYS A NZ  1 
ATOM 3357 N N   . LYS B 2 167 ? 156.334 77.545  136.009 1.00 129.91 ? 281 LYS A N   1 
ATOM 3358 C CA  . LYS B 2 167 ? 156.284 76.756  137.235 1.00 131.42 ? 281 LYS A CA  1 
ATOM 3359 C C   . LYS B 2 167 ? 154.897 76.166  137.462 1.00 130.81 ? 281 LYS A C   1 
ATOM 3360 O O   . LYS B 2 167 ? 154.769 74.997  137.843 1.00 129.19 ? 281 LYS A O   1 
ATOM 3361 C CB  . LYS B 2 167 ? 156.705 77.614  138.428 1.00 129.52 ? 281 LYS A CB  1 
ATOM 3362 N N   . SER B 2 168 ? 153.850 76.955  137.231 1.00 131.89 ? 282 SER A N   1 
ATOM 3363 C CA  . SER B 2 168 ? 152.475 76.519  137.457 1.00 131.22 ? 282 SER A CA  1 
ATOM 3364 C C   . SER B 2 168 ? 151.637 76.882  136.240 1.00 132.47 ? 282 SER A C   1 
ATOM 3365 O O   . SER B 2 168 ? 151.554 78.075  135.882 1.00 132.07 ? 282 SER A O   1 
ATOM 3366 C CB  . SER B 2 168 ? 151.900 77.155  138.725 1.00 130.69 ? 282 SER A CB  1 
ATOM 3367 O OG  . SER B 2 168 ? 152.148 78.550  138.751 1.00 130.80 ? 282 SER A OG  1 
ATOM 3368 N N   . PRO B 2 169 ? 151.003 75.916  135.579 1.00 132.59 ? 283 PRO A N   1 
ATOM 3369 C CA  . PRO B 2 169 ? 150.174 76.240  134.414 1.00 129.98 ? 283 PRO A CA  1 
ATOM 3370 C C   . PRO B 2 169 ? 148.942 77.039  134.805 1.00 130.39 ? 283 PRO A C   1 
ATOM 3371 O O   . PRO B 2 169 ? 148.439 76.948  135.927 1.00 130.71 ? 283 PRO A O   1 
ATOM 3372 C CB  . PRO B 2 169 ? 149.790 74.865  133.857 1.00 129.90 ? 283 PRO A CB  1 
ATOM 3373 C CG  . PRO B 2 169 ? 149.875 73.949  135.030 1.00 130.76 ? 283 PRO A CG  1 
ATOM 3374 C CD  . PRO B 2 169 ? 150.980 74.478  135.900 1.00 131.15 ? 283 PRO A CD  1 
ATOM 3375 N N   . LEU B 2 170 ? 148.452 77.834  133.850 1.00 129.05 ? 284 LEU A N   1 
ATOM 3376 C CA  . LEU B 2 170 ? 147.279 78.683  134.065 1.00 130.67 ? 284 LEU A CA  1 
ATOM 3377 C C   . LEU B 2 170 ? 146.015 77.821  134.019 1.00 129.93 ? 284 LEU A C   1 
ATOM 3378 O O   . LEU B 2 170 ? 145.198 77.885  133.098 1.00 129.07 ? 284 LEU A O   1 
ATOM 3379 C CB  . LEU B 2 170 ? 147.238 79.804  133.035 1.00 129.73 ? 284 LEU A CB  1 
ATOM 3380 C CG  . LEU B 2 170 ? 146.179 80.893  133.229 1.00 128.62 ? 284 LEU A CG  1 
ATOM 3381 C CD1 . LEU B 2 170 ? 146.305 81.526  134.602 1.00 130.24 ? 284 LEU A CD1 1 
ATOM 3382 C CD2 . LEU B 2 170 ? 146.287 81.947  132.138 1.00 125.80 ? 284 LEU A CD2 1 
ATOM 3383 N N   . THR B 2 171 ? 145.873 76.984  135.045 1.00 134.23 ? 285 THR A N   1 
ATOM 3384 C CA  . THR B 2 171 ? 144.709 76.119  135.183 1.00 133.63 ? 285 THR A CA  1 
ATOM 3385 C C   . THR B 2 171 ? 144.106 76.103  136.579 1.00 133.84 ? 285 THR A C   1 
ATOM 3386 O O   . THR B 2 171 ? 142.933 75.733  136.711 1.00 132.76 ? 285 THR A O   1 
ATOM 3387 C CB  . THR B 2 171 ? 145.058 74.676  134.786 1.00 134.27 ? 285 THR A CB  1 
ATOM 3388 O OG1 . THR B 2 171 ? 143.900 73.844  134.933 1.00 133.79 ? 285 THR A OG1 1 
ATOM 3389 C CG2 . THR B 2 171 ? 146.180 74.135  135.661 1.00 133.00 ? 285 THR A CG2 1 
ATOM 3390 N N   . ILE B 2 172 ? 144.854 76.481  137.618 1.00 134.75 ? 286 ILE A N   1 
ATOM 3391 C CA  . ILE B 2 172 ? 144.311 76.445  138.972 1.00 134.54 ? 286 ILE A CA  1 
ATOM 3392 C C   . ILE B 2 172 ? 143.225 77.499  139.145 1.00 133.85 ? 286 ILE A C   1 
ATOM 3393 O O   . ILE B 2 172 ? 142.179 77.237  139.753 1.00 132.64 ? 286 ILE A O   1 
ATOM 3394 C CB  . ILE B 2 172 ? 145.439 76.611  140.008 1.00 133.64 ? 286 ILE A CB  1 
ATOM 3395 C CG1 . ILE B 2 172 ? 146.396 77.730  139.593 1.00 132.64 ? 286 ILE A CG1 1 
ATOM 3396 C CG2 . ILE B 2 172 ? 146.193 75.302  140.189 1.00 132.67 ? 286 ILE A CG2 1 
ATOM 3397 C CD1 . ILE B 2 172 ? 147.484 78.005  140.608 1.00 132.85 ? 286 ILE A CD1 1 
ATOM 3398 N N   . CYS B 2 173 ? 143.448 78.704  138.621 1.00 131.75 ? 287 CYS A N   1 
ATOM 3399 C CA  . CYS B 2 173 ? 142.446 79.758  138.716 1.00 130.26 ? 287 CYS A CA  1 
ATOM 3400 C C   . CYS B 2 173 ? 141.473 79.745  137.546 1.00 129.90 ? 287 CYS A C   1 
ATOM 3401 O O   . CYS B 2 173 ? 140.305 80.109  137.719 1.00 129.53 ? 287 CYS A O   1 
ATOM 3402 C CB  . CYS B 2 173 ? 143.122 81.128  138.807 1.00 131.83 ? 287 CYS A CB  1 
ATOM 3403 S SG  . CYS B 2 173 ? 141.968 82.520  138.859 1.00 134.91 ? 287 CYS A SG  1 
ATOM 3404 N N   . PHE B 2 174 ? 141.918 79.322  136.362 1.00 125.84 ? 288 PHE A N   1 
ATOM 3405 C CA  . PHE B 2 174 ? 141.059 79.193  135.185 1.00 126.40 ? 288 PHE A CA  1 
ATOM 3406 C C   . PHE B 2 174 ? 141.014 77.726  134.781 1.00 127.69 ? 288 PHE A C   1 
ATOM 3407 O O   . PHE B 2 174 ? 141.783 77.286  133.912 1.00 127.79 ? 288 PHE A O   1 
ATOM 3408 C CB  . PHE B 2 174 ? 141.556 80.065  134.034 1.00 125.39 ? 288 PHE A CB  1 
ATOM 3409 C CG  . PHE B 2 174 ? 141.075 81.487  134.097 1.00 124.97 ? 288 PHE A CG  1 
ATOM 3410 C CD1 . PHE B 2 174 ? 139.793 81.814  133.688 1.00 123.58 ? 288 PHE A CD1 1 
ATOM 3411 C CD2 . PHE B 2 174 ? 141.903 82.496  134.557 1.00 124.14 ? 288 PHE A CD2 1 
ATOM 3412 C CE1 . PHE B 2 174 ? 139.344 83.119  133.741 1.00 121.24 ? 288 PHE A CE1 1 
ATOM 3413 C CE2 . PHE B 2 174 ? 141.458 83.804  134.611 1.00 123.69 ? 288 PHE A CE2 1 
ATOM 3414 C CZ  . PHE B 2 174 ? 140.177 84.114  134.203 1.00 122.87 ? 288 PHE A CZ  1 
ATOM 3415 N N   . PRO B 2 175 ? 140.131 76.928  135.389 1.00 134.61 ? 289 PRO A N   1 
ATOM 3416 C CA  . PRO B 2 175 ? 140.021 75.518  134.987 1.00 133.58 ? 289 PRO A CA  1 
ATOM 3417 C C   . PRO B 2 175 ? 139.448 75.327  133.595 1.00 132.43 ? 289 PRO A C   1 
ATOM 3418 O O   . PRO B 2 175 ? 139.597 74.238  133.027 1.00 133.09 ? 289 PRO A O   1 
ATOM 3419 C CB  . PRO B 2 175 ? 139.101 74.918  136.058 1.00 133.64 ? 289 PRO A CB  1 
ATOM 3420 C CG  . PRO B 2 175 ? 138.290 76.074  136.540 1.00 133.62 ? 289 PRO A CG  1 
ATOM 3421 C CD  . PRO B 2 175 ? 139.192 77.275  136.471 1.00 133.32 ? 289 PRO A CD  1 
ATOM 3422 N N   . GLU B 2 176 ? 138.801 76.343  133.029 1.00 124.22 ? 290 GLU A N   1 
ATOM 3423 C CA  . GLU B 2 176 ? 138.196 76.240  131.708 1.00 124.31 ? 290 GLU A CA  1 
ATOM 3424 C C   . GLU B 2 176 ? 139.198 76.428  130.577 1.00 125.71 ? 290 GLU A C   1 
ATOM 3425 O O   . GLU B 2 176 ? 138.820 76.285  129.409 1.00 126.13 ? 290 GLU A O   1 
ATOM 3426 C CB  . GLU B 2 176 ? 137.065 77.264  131.571 1.00 126.98 ? 290 GLU A CB  1 
ATOM 3427 C CG  . GLU B 2 176 ? 136.491 77.733  132.898 1.00 127.77 ? 290 GLU A CG  1 
ATOM 3428 C CD  . GLU B 2 176 ? 135.124 78.373  132.750 1.00 128.79 ? 290 GLU A CD  1 
ATOM 3429 O OE1 . GLU B 2 176 ? 134.933 79.162  131.801 1.00 127.47 ? 290 GLU A OE1 1 
ATOM 3430 O OE2 . GLU B 2 176 ? 134.239 78.087  133.584 1.00 129.32 ? 290 GLU A OE2 1 
ATOM 3431 N N   . TYR B 2 177 ? 140.452 76.749  130.887 1.00 118.59 ? 291 TYR A N   1 
ATOM 3432 C CA  . TYR B 2 177 ? 141.453 76.958  129.851 1.00 118.15 ? 291 TYR A CA  1 
ATOM 3433 C C   . TYR B 2 177 ? 141.734 75.670  129.086 1.00 119.41 ? 291 TYR A C   1 
ATOM 3434 O O   . TYR B 2 177 ? 141.779 74.580  129.662 1.00 118.48 ? 291 TYR A O   1 
ATOM 3435 C CB  . TYR B 2 177 ? 142.748 77.495  130.458 1.00 117.14 ? 291 TYR A CB  1 
ATOM 3436 C CG  . TYR B 2 177 ? 143.574 78.308  129.489 1.00 116.87 ? 291 TYR A CG  1 
ATOM 3437 C CD1 . TYR B 2 177 ? 143.036 78.743  128.285 1.00 115.59 ? 291 TYR A CD1 1 
ATOM 3438 C CD2 . TYR B 2 177 ? 144.895 78.629  129.770 1.00 118.27 ? 291 TYR A CD2 1 
ATOM 3439 C CE1 . TYR B 2 177 ? 143.785 79.477  127.392 1.00 117.80 ? 291 TYR A CE1 1 
ATOM 3440 C CE2 . TYR B 2 177 ? 145.654 79.367  128.882 1.00 117.73 ? 291 TYR A CE2 1 
ATOM 3441 C CZ  . TYR B 2 177 ? 145.093 79.788  127.695 1.00 119.30 ? 291 TYR A CZ  1 
ATOM 3442 O OH  . TYR B 2 177 ? 145.839 80.522  126.803 1.00 119.27 ? 291 TYR A OH  1 
ATOM 3443 N N   . THR B 2 178 ? 141.922 75.809  127.774 1.00 126.05 ? 292 THR A N   1 
ATOM 3444 C CA  . THR B 2 178 ? 142.229 74.686  126.899 1.00 126.00 ? 292 THR A CA  1 
ATOM 3445 C C   . THR B 2 178 ? 143.387 74.951  125.945 1.00 125.03 ? 292 THR A C   1 
ATOM 3446 O O   . THR B 2 178 ? 143.957 73.987  125.420 1.00 123.97 ? 292 THR A O   1 
ATOM 3447 C CB  . THR B 2 178 ? 140.990 74.296  126.075 1.00 125.29 ? 292 THR A CB  1 
ATOM 3448 O OG1 . THR B 2 178 ? 139.814 74.463  126.876 1.00 123.95 ? 292 THR A OG1 1 
ATOM 3449 C CG2 . THR B 2 178 ? 141.073 72.844  125.625 1.00 123.93 ? 292 THR A CG2 1 
ATOM 3450 N N   . GLY B 2 179 ? 143.766 76.209  125.718 1.00 122.28 ? 293 GLY A N   1 
ATOM 3451 C CA  . GLY B 2 179 ? 144.778 76.530  124.742 1.00 120.95 ? 293 GLY A CA  1 
ATOM 3452 C C   . GLY B 2 179 ? 146.177 76.243  125.238 1.00 121.02 ? 293 GLY A C   1 
ATOM 3453 O O   . GLY B 2 179 ? 146.398 75.727  126.342 1.00 120.03 ? 293 GLY A O   1 
ATOM 3454 N N   . PRO B 2 180 ? 147.158 76.578  124.399 1.00 125.51 ? 294 PRO A N   1 
ATOM 3455 C CA  . PRO B 2 180 ? 148.557 76.306  124.749 1.00 125.63 ? 294 PRO A CA  1 
ATOM 3456 C C   . PRO B 2 180 ? 149.003 77.109  125.962 1.00 125.02 ? 294 PRO A C   1 
ATOM 3457 O O   . PRO B 2 180 ? 148.481 78.188  126.251 1.00 123.90 ? 294 PRO A O   1 
ATOM 3458 C CB  . PRO B 2 180 ? 149.327 76.723  123.490 1.00 124.96 ? 294 PRO A CB  1 
ATOM 3459 C CG  . PRO B 2 180 ? 148.306 76.722  122.391 1.00 124.76 ? 294 PRO A CG  1 
ATOM 3460 C CD  . PRO B 2 180 ? 147.023 77.130  123.042 1.00 124.57 ? 294 PRO A CD  1 
ATOM 3461 N N   . ASN B 2 181 ? 149.983 76.560  126.676 1.00 127.90 ? 295 ASN A N   1 
ATOM 3462 C CA  . ASN B 2 181 ? 150.506 77.162  127.896 1.00 128.63 ? 295 ASN A CA  1 
ATOM 3463 C C   . ASN B 2 181 ? 151.558 78.235  127.635 1.00 127.09 ? 295 ASN A C   1 
ATOM 3464 O O   . ASN B 2 181 ? 152.276 78.613  128.566 1.00 125.94 ? 295 ASN A O   1 
ATOM 3465 C CB  . ASN B 2 181 ? 151.094 76.075  128.802 1.00 128.31 ? 295 ASN A CB  1 
ATOM 3466 C CG  . ASN B 2 181 ? 150.995 76.425  130.273 1.00 128.29 ? 295 ASN A CG  1 
ATOM 3467 O OD1 . ASN B 2 181 ? 150.443 77.461  130.641 1.00 128.10 ? 295 ASN A OD1 1 
ATOM 3468 N ND2 . ASN B 2 181 ? 151.536 75.561  131.124 1.00 127.62 ? 295 ASN A ND2 1 
ATOM 3469 N N   . THR B 2 182 ? 151.671 78.730  126.406 1.00 125.18 ? 296 THR A N   1 
ATOM 3470 C CA  . THR B 2 182 ? 152.657 79.759  126.114 1.00 126.37 ? 296 THR A CA  1 
ATOM 3471 C C   . THR B 2 182 ? 152.219 81.104  126.691 1.00 126.09 ? 296 THR A C   1 
ATOM 3472 O O   . THR B 2 182 ? 151.064 81.302  127.078 1.00 123.66 ? 296 THR A O   1 
ATOM 3473 C CB  . THR B 2 182 ? 152.885 79.880  124.606 1.00 125.58 ? 296 THR A CB  1 
ATOM 3474 O OG1 . THR B 2 182 ? 153.957 80.797  124.355 1.00 123.72 ? 296 THR A OG1 1 
ATOM 3475 C CG2 . THR B 2 182 ? 151.631 80.380  123.917 1.00 123.98 ? 296 THR A CG2 1 
ATOM 3476 N N   . TYR B 2 183 ? 153.174 82.034  126.753 1.00 118.31 ? 297 TYR A N   1 
ATOM 3477 C CA  . TYR B 2 183 ? 152.915 83.335  127.362 1.00 116.50 ? 297 TYR A CA  1 
ATOM 3478 C C   . TYR B 2 183 ? 151.882 84.127  126.570 1.00 115.05 ? 297 TYR A C   1 
ATOM 3479 O O   . TYR B 2 183 ? 150.939 84.688  127.143 1.00 117.82 ? 297 TYR A O   1 
ATOM 3480 C CB  . TYR B 2 183 ? 154.224 84.117  127.479 1.00 115.45 ? 297 TYR A CB  1 
ATOM 3481 C CG  . TYR B 2 183 ? 154.049 85.591  127.773 1.00 117.56 ? 297 TYR A CG  1 
ATOM 3482 C CD1 . TYR B 2 183 ? 153.718 86.030  129.049 1.00 117.87 ? 297 TYR A CD1 1 
ATOM 3483 C CD2 . TYR B 2 183 ? 154.224 86.543  126.777 1.00 116.67 ? 297 TYR A CD2 1 
ATOM 3484 C CE1 . TYR B 2 183 ? 153.560 87.376  129.322 1.00 118.28 ? 297 TYR A CE1 1 
ATOM 3485 C CE2 . TYR B 2 183 ? 154.068 87.891  127.041 1.00 116.19 ? 297 TYR A CE2 1 
ATOM 3486 C CZ  . TYR B 2 183 ? 153.736 88.302  128.314 1.00 116.35 ? 297 TYR A CZ  1 
ATOM 3487 O OH  . TYR B 2 183 ? 153.580 89.642  128.581 1.00 113.93 ? 297 TYR A OH  1 
ATOM 3488 N N   . GLU B 2 184 ? 152.042 84.180  125.245 1.00 113.68 ? 298 GLU A N   1 
ATOM 3489 C CA  . GLU B 2 184 ? 151.175 85.019  124.422 1.00 115.87 ? 298 GLU A CA  1 
ATOM 3490 C C   . GLU B 2 184 ? 149.724 84.556  124.491 1.00 117.06 ? 298 GLU A C   1 
ATOM 3491 O O   . GLU B 2 184 ? 148.810 85.368  124.676 1.00 118.27 ? 298 GLU A O   1 
ATOM 3492 C CB  . GLU B 2 184 ? 151.668 85.022  122.975 1.00 117.08 ? 298 GLU A CB  1 
ATOM 3493 C CG  . GLU B 2 184 ? 152.764 86.036  122.685 1.00 117.83 ? 298 GLU A CG  1 
ATOM 3494 C CD  . GLU B 2 184 ? 154.134 85.556  123.120 1.00 119.76 ? 298 GLU A CD  1 
ATOM 3495 O OE1 . GLU B 2 184 ? 154.303 84.335  123.317 1.00 121.58 ? 298 GLU A OE1 1 
ATOM 3496 O OE2 . GLU B 2 184 ? 155.044 86.400  123.262 1.00 118.68 ? 298 GLU A OE2 1 
ATOM 3497 N N   . ASP B 2 185 ? 149.494 83.249  124.343 1.00 113.46 ? 299 ASP A N   1 
ATOM 3498 C CA  . ASP B 2 185 ? 148.125 82.740  124.342 1.00 112.28 ? 299 ASP A CA  1 
ATOM 3499 C C   . ASP B 2 185 ? 147.465 82.905  125.705 1.00 111.66 ? 299 ASP A C   1 
ATOM 3500 O O   . ASP B 2 185 ? 146.285 83.262  125.786 1.00 109.64 ? 299 ASP A O   1 
ATOM 3501 C CB  . ASP B 2 185 ? 148.107 81.277  123.904 1.00 112.01 ? 299 ASP A CB  1 
ATOM 3502 C CG  . ASP B 2 185 ? 148.609 81.089  122.487 1.00 112.90 ? 299 ASP A CG  1 
ATOM 3503 O OD1 . ASP B 2 185 ? 149.015 82.091  121.863 1.00 113.27 ? 299 ASP A OD1 1 
ATOM 3504 O OD2 . ASP B 2 185 ? 148.597 79.941  121.998 1.00 112.57 ? 299 ASP A OD2 1 
ATOM 3505 N N   . ALA B 2 186 ? 148.204 82.650  126.787 1.00 108.41 ? 300 ALA A N   1 
ATOM 3506 C CA  . ALA B 2 186 ? 147.639 82.835  128.120 1.00 109.56 ? 300 ALA A CA  1 
ATOM 3507 C C   . ALA B 2 186 ? 147.291 84.296  128.375 1.00 109.10 ? 300 ALA A C   1 
ATOM 3508 O O   . ALA B 2 186 ? 146.221 84.605  128.917 1.00 107.12 ? 300 ALA A O   1 
ATOM 3509 C CB  . ALA B 2 186 ? 148.615 82.323  129.179 1.00 109.65 ? 300 ALA A CB  1 
ATOM 3510 N N   . ALA B 2 187 ? 148.184 85.210  127.987 1.00 99.41  ? 301 ALA A N   1 
ATOM 3511 C CA  . ALA B 2 187 ? 147.904 86.630  128.164 1.00 94.96  ? 301 ALA A CA  1 
ATOM 3512 C C   . ALA B 2 187 ? 146.692 87.057  127.347 1.00 96.32  ? 301 ALA A C   1 
ATOM 3513 O O   . ALA B 2 187 ? 145.846 87.820  127.828 1.00 96.82  ? 301 ALA A O   1 
ATOM 3514 C CB  . ALA B 2 187 ? 149.133 87.454  127.785 1.00 94.18  ? 301 ALA A CB  1 
ATOM 3515 N N   . ALA B 2 188 ? 146.585 86.564  126.110 1.00 94.09  ? 302 ALA A N   1 
ATOM 3516 C CA  . ALA B 2 188 ? 145.431 86.894  125.281 1.00 92.54  ? 302 ALA A CA  1 
ATOM 3517 C C   . ALA B 2 188 ? 144.146 86.328  125.872 1.00 91.79  ? 302 ALA A C   1 
ATOM 3518 O O   . ALA B 2 188 ? 143.086 86.953  125.782 1.00 90.98  ? 302 ALA A O   1 
ATOM 3519 C CB  . ALA B 2 188 ? 145.641 86.378  123.858 1.00 92.25  ? 302 ALA A CB  1 
ATOM 3520 N N   . TYR B 2 189 ? 144.220 85.141  126.475 1.00 96.59  ? 303 TYR A N   1 
ATOM 3521 C CA  . TYR B 2 189 ? 143.046 84.544  127.105 1.00 98.56  ? 303 TYR A CA  1 
ATOM 3522 C C   . TYR B 2 189 ? 142.583 85.371  128.301 1.00 98.10  ? 303 TYR A C   1 
ATOM 3523 O O   . TYR B 2 189 ? 141.379 85.611  128.475 1.00 98.72  ? 303 TYR A O   1 
ATOM 3524 C CB  . TYR B 2 189 ? 143.379 83.112  127.521 1.00 99.28  ? 303 TYR A CB  1 
ATOM 3525 C CG  . TYR B 2 189 ? 142.268 82.347  128.201 1.00 97.70  ? 303 TYR A CG  1 
ATOM 3526 C CD1 . TYR B 2 189 ? 141.207 81.833  127.470 1.00 96.83  ? 303 TYR A CD1 1 
ATOM 3527 C CD2 . TYR B 2 189 ? 142.292 82.121  129.569 1.00 98.08  ? 303 TYR A CD2 1 
ATOM 3528 C CE1 . TYR B 2 189 ? 140.200 81.118  128.083 1.00 97.57  ? 303 TYR A CE1 1 
ATOM 3529 C CE2 . TYR B 2 189 ? 141.286 81.413  130.193 1.00 97.81  ? 303 TYR A CE2 1 
ATOM 3530 C CZ  . TYR B 2 189 ? 140.243 80.913  129.446 1.00 98.04  ? 303 TYR A CZ  1 
ATOM 3531 O OH  . TYR B 2 189 ? 139.237 80.208  130.064 1.00 99.96  ? 303 TYR A OH  1 
ATOM 3532 N N   . ILE B 2 190 ? 143.528 85.821  129.132 1.00 88.98  ? 304 ILE A N   1 
ATOM 3533 C CA  . ILE B 2 190 ? 143.175 86.684  130.259 1.00 84.39  ? 304 ILE A CA  1 
ATOM 3534 C C   . ILE B 2 190 ? 142.580 87.995  129.760 1.00 82.48  ? 304 ILE A C   1 
ATOM 3535 O O   . ILE B 2 190 ? 141.591 88.497  130.311 1.00 84.30  ? 304 ILE A O   1 
ATOM 3536 C CB  . ILE B 2 190 ? 144.398 86.927  131.161 1.00 83.34  ? 304 ILE A CB  1 
ATOM 3537 C CG1 . ILE B 2 190 ? 145.002 85.596  131.614 1.00 86.25  ? 304 ILE A CG1 1 
ATOM 3538 C CG2 . ILE B 2 190 ? 144.011 87.784  132.356 1.00 85.72  ? 304 ILE A CG2 1 
ATOM 3539 C CD1 . ILE B 2 190 ? 145.812 85.687  132.890 1.00 87.50  ? 304 ILE A CD1 1 
ATOM 3540 N N   . GLN B 2 191 ? 143.172 88.570  128.711 1.00 75.17  ? 305 GLN A N   1 
ATOM 3541 C CA  . GLN B 2 191 ? 142.627 89.793  128.133 1.00 72.32  ? 305 GLN A CA  1 
ATOM 3542 C C   . GLN B 2 191 ? 141.215 89.572  127.605 1.00 74.82  ? 305 GLN A C   1 
ATOM 3543 O O   . GLN B 2 191 ? 140.350 90.446  127.736 1.00 78.34  ? 305 GLN A O   1 
ATOM 3544 C CB  . GLN B 2 191 ? 143.544 90.296  127.018 1.00 76.69  ? 305 GLN A CB  1 
ATOM 3545 C CG  . GLN B 2 191 ? 143.079 91.587  126.379 1.00 74.14  ? 305 GLN A CG  1 
ATOM 3546 C CD  . GLN B 2 191 ? 143.020 92.732  127.367 1.00 78.55  ? 305 GLN A CD  1 
ATOM 3547 O OE1 . GLN B 2 191 ? 142.135 93.584  127.297 1.00 79.66  ? 305 GLN A OE1 1 
ATOM 3548 N NE2 . GLN B 2 191 ? 143.975 92.766  128.289 1.00 78.31  ? 305 GLN A NE2 1 
ATOM 3549 N N   . ALA B 2 192 ? 140.967 88.412  126.993 1.00 79.46  ? 306 ALA A N   1 
ATOM 3550 C CA  . ALA B 2 192 ? 139.642 88.110  126.465 1.00 79.33  ? 306 ALA A CA  1 
ATOM 3551 C C   . ALA B 2 192 ? 138.610 88.000  127.578 1.00 78.93  ? 306 ALA A C   1 
ATOM 3552 O O   . ALA B 2 192 ? 137.499 88.525  127.452 1.00 80.83  ? 306 ALA A O   1 
ATOM 3553 C CB  . ALA B 2 192 ? 139.687 86.821  125.646 1.00 78.66  ? 306 ALA A CB  1 
ATOM 3554 N N   . GLN B 2 193 ? 138.951 87.317  128.675 1.00 84.01  ? 307 GLN A N   1 
ATOM 3555 C CA  . GLN B 2 193 ? 138.009 87.253  129.792 1.00 83.54  ? 307 GLN A CA  1 
ATOM 3556 C C   . GLN B 2 193 ? 137.822 88.602  130.473 1.00 81.25  ? 307 GLN A C   1 
ATOM 3557 O O   . GLN B 2 193 ? 136.753 88.859  131.038 1.00 83.28  ? 307 GLN A O   1 
ATOM 3558 C CB  . GLN B 2 193 ? 138.429 86.190  130.807 1.00 81.44  ? 307 GLN A CB  1 
ATOM 3559 C CG  . GLN B 2 193 ? 138.878 84.885  130.191 1.00 84.77  ? 307 GLN A CG  1 
ATOM 3560 C CD  . GLN B 2 193 ? 137.698 84.069  129.681 1.00 87.40  ? 307 GLN A CD  1 
ATOM 3561 O OE1 . GLN B 2 193 ? 136.556 84.528  129.696 1.00 89.80  ? 307 GLN A OE1 1 
ATOM 3562 N NE2 . GLN B 2 193 ? 137.969 82.855  129.232 1.00 83.55  ? 307 GLN A NE2 1 
ATOM 3563 N N   . PHE B 2 194 ? 138.831 89.475  130.441 1.00 75.30  ? 308 PHE A N   1 
ATOM 3564 C CA  . PHE B 2 194 ? 138.628 90.811  130.993 1.00 71.41  ? 308 PHE A CA  1 
ATOM 3565 C C   . PHE B 2 194 ? 137.756 91.675  130.089 1.00 70.64  ? 308 PHE A C   1 
ATOM 3566 O O   . PHE B 2 194 ? 136.980 92.497  130.587 1.00 70.21  ? 308 PHE A O   1 
ATOM 3567 C CB  . PHE B 2 194 ? 139.970 91.491  131.253 1.00 71.72  ? 308 PHE A CB  1 
ATOM 3568 C CG  . PHE B 2 194 ? 140.463 91.324  132.658 1.00 67.61  ? 308 PHE A CG  1 
ATOM 3569 C CD1 . PHE B 2 194 ? 139.915 92.071  133.685 1.00 67.06  ? 308 PHE A CD1 1 
ATOM 3570 C CD2 . PHE B 2 194 ? 141.466 90.420  132.955 1.00 73.70  ? 308 PHE A CD2 1 
ATOM 3571 C CE1 . PHE B 2 194 ? 140.361 91.922  134.979 1.00 72.00  ? 308 PHE A CE1 1 
ATOM 3572 C CE2 . PHE B 2 194 ? 141.916 90.267  134.250 1.00 71.02  ? 308 PHE A CE2 1 
ATOM 3573 C CZ  . PHE B 2 194 ? 141.362 91.019  135.262 1.00 73.93  ? 308 PHE A CZ  1 
ATOM 3574 N N   . GLU B 2 195 ? 137.871 91.515  128.771 1.00 70.99  ? 309 GLU A N   1 
ATOM 3575 C CA  . GLU B 2 195 ? 137.029 92.268  127.849 1.00 69.13  ? 309 GLU A CA  1 
ATOM 3576 C C   . GLU B 2 195 ? 135.621 91.700  127.730 1.00 76.49  ? 309 GLU A C   1 
ATOM 3577 O O   . GLU B 2 195 ? 134.712 92.423  127.309 1.00 77.28  ? 309 GLU A O   1 
ATOM 3578 C CB  . GLU B 2 195 ? 137.671 92.318  126.461 1.00 70.59  ? 309 GLU A CB  1 
ATOM 3579 C CG  . GLU B 2 195 ? 138.758 93.367  126.310 1.00 71.85  ? 309 GLU A CG  1 
ATOM 3580 C CD  . GLU B 2 195 ? 139.352 93.388  124.916 1.00 77.33  ? 309 GLU A CD  1 
ATOM 3581 O OE1 . GLU B 2 195 ? 140.066 94.357  124.586 1.00 72.68  ? 309 GLU A OE1 1 
ATOM 3582 O OE2 . GLU B 2 195 ? 139.101 92.436  124.148 1.00 81.85  ? 309 GLU A OE2 1 
ATOM 3583 N N   . SER B 2 196 ? 135.422 90.428  128.082 1.00 79.73  ? 310 SER A N   1 
ATOM 3584 C CA  . SER B 2 196 ? 134.108 89.809  127.944 1.00 76.60  ? 310 SER A CA  1 
ATOM 3585 C C   . SER B 2 196 ? 133.089 90.355  128.935 1.00 78.51  ? 310 SER A C   1 
ATOM 3586 O O   . SER B 2 196 ? 131.888 90.141  128.746 1.00 79.73  ? 310 SER A O   1 
ATOM 3587 C CB  . SER B 2 196 ? 134.224 88.293  128.107 1.00 78.10  ? 310 SER A CB  1 
ATOM 3588 O OG  . SER B 2 196 ? 132.955 87.708  128.337 1.00 84.17  ? 310 SER A OG  1 
ATOM 3589 N N   . LYS B 2 197 ? 133.533 91.050  129.978 1.00 84.14  ? 311 LYS A N   1 
ATOM 3590 C CA  . LYS B 2 197 ? 132.629 91.637  130.957 1.00 82.66  ? 311 LYS A CA  1 
ATOM 3591 C C   . LYS B 2 197 ? 132.143 93.023  130.557 1.00 84.75  ? 311 LYS A C   1 
ATOM 3592 O O   . LYS B 2 197 ? 131.416 93.652  131.332 1.00 85.36  ? 311 LYS A O   1 
ATOM 3593 C CB  . LYS B 2 197 ? 133.304 91.708  132.329 1.00 79.80  ? 311 LYS A CB  1 
ATOM 3594 C CG  . LYS B 2 197 ? 133.848 90.382  132.826 1.00 78.51  ? 311 LYS A CG  1 
ATOM 3595 C CD  . LYS B 2 197 ? 132.729 89.509  133.366 1.00 82.37  ? 311 LYS A CD  1 
ATOM 3596 C CE  . LYS B 2 197 ? 133.258 88.452  134.318 1.00 84.43  ? 311 LYS A CE  1 
ATOM 3597 N NZ  . LYS B 2 197 ? 133.971 87.362  133.599 1.00 87.85  ? 311 LYS A NZ  1 
ATOM 3598 N N   . ASN B 2 198 ? 132.531 93.514  129.380 1.00 82.47  ? 312 ASN A N   1 
ATOM 3599 C CA  . ASN B 2 198 ? 132.106 94.829  128.918 1.00 81.12  ? 312 ASN A CA  1 
ATOM 3600 C C   . ASN B 2 198 ? 130.590 94.873  128.771 1.00 86.45  ? 312 ASN A C   1 
ATOM 3601 O O   . ASN B 2 198 ? 129.914 95.591  129.514 1.00 85.61  ? 312 ASN A O   1 
ATOM 3602 C CB  . ASN B 2 198 ? 132.798 95.169  127.594 1.00 79.57  ? 312 ASN A CB  1 
ATOM 3603 C CG  . ASN B 2 198 ? 132.440 96.549  127.080 1.00 83.23  ? 312 ASN A CG  1 
ATOM 3604 O OD1 . ASN B 2 198 ? 131.303 96.806  126.689 1.00 86.04  ? 312 ASN A OD1 1 
ATOM 3605 N ND2 . ASN B 2 198 ? 133.418 97.447  127.072 1.00 80.45  ? 312 ASN A ND2 1 
ATOM 3606 N N   . ARG B 2 199 ? 130.055 94.100  127.823 1.00 96.16  ? 313 ARG A N   1 
ATOM 3607 C CA  . ARG B 2 199 ? 128.610 93.903  127.675 1.00 94.44  ? 313 ARG A CA  1 
ATOM 3608 C C   . ARG B 2 199 ? 127.860 95.230  127.586 1.00 92.82  ? 313 ARG A C   1 
ATOM 3609 O O   . ARG B 2 199 ? 126.769 95.389  128.139 1.00 94.51  ? 313 ARG A O   1 
ATOM 3610 C CB  . ARG B 2 199 ? 128.060 93.052  128.821 1.00 94.92  ? 313 ARG A CB  1 
ATOM 3611 C CG  . ARG B 2 199 ? 126.859 92.199  128.448 1.00 95.38  ? 313 ARG A CG  1 
ATOM 3612 C CD  . ARG B 2 199 ? 126.501 91.249  129.577 1.00 95.13  ? 313 ARG A CD  1 
ATOM 3613 N NE  . ARG B 2 199 ? 125.988 91.967  130.738 1.00 96.52  ? 313 ARG A NE  1 
ATOM 3614 C CZ  . ARG B 2 199 ? 126.528 91.918  131.948 1.00 98.59  ? 313 ARG A CZ  1 
ATOM 3615 N NH1 . ARG B 2 199 ? 127.600 91.185  132.198 1.00 97.85  ? 313 ARG A NH1 1 
ATOM 3616 N NH2 . ARG B 2 199 ? 125.977 92.623  132.932 1.00 96.83  ? 313 ARG A NH2 1 
ATOM 3617 N N   . SER B 2 200 ? 128.448 96.200  126.885 1.00 86.97  ? 314 SER A N   1 
ATOM 3618 C CA  . SER B 2 200 ? 127.830 97.512  126.820 1.00 88.53  ? 314 SER A CA  1 
ATOM 3619 C C   . SER B 2 200 ? 128.266 98.256  125.569 1.00 90.41  ? 314 SER A C   1 
ATOM 3620 O O   . SER B 2 200 ? 129.433 98.146  125.166 1.00 89.69  ? 314 SER A O   1 
ATOM 3621 C CB  . SER B 2 200 ? 128.178 98.343  128.060 1.00 92.36  ? 314 SER A CB  1 
ATOM 3622 O OG  . SER B 2 200 ? 127.431 99.546  128.098 1.00 94.53  ? 314 SER A OG  1 
ATOM 3623 N N   . PRO B 2 201 ? 127.370 99.007  124.940 1.00 93.99  ? 315 PRO A N   1 
ATOM 3624 C CA  . PRO B 2 201 ? 127.772 99.878  123.835 1.00 94.05  ? 315 PRO A CA  1 
ATOM 3625 C C   . PRO B 2 201 ? 128.311 101.198 124.369 1.00 93.65  ? 315 PRO A C   1 
ATOM 3626 O O   . PRO B 2 201 ? 128.287 101.470 125.570 1.00 91.86  ? 315 PRO A O   1 
ATOM 3627 C CB  . PRO B 2 201 ? 126.475 100.083 123.046 1.00 91.71  ? 315 PRO A CB  1 
ATOM 3628 C CG  . PRO B 2 201 ? 125.360 99.767  124.015 1.00 89.60  ? 315 PRO A CG  1 
ATOM 3629 C CD  . PRO B 2 201 ? 125.939 99.139  125.257 1.00 88.73  ? 315 PRO A CD  1 
ATOM 3630 N N   . ASN B 2 202 ? 128.818 102.015 123.445 1.00 81.49  ? 316 ASN A N   1 
ATOM 3631 C CA  . ASN B 2 202 ? 129.346 103.342 123.758 1.00 78.66  ? 316 ASN A CA  1 
ATOM 3632 C C   . ASN B 2 202 ? 130.542 103.292 124.701 1.00 78.44  ? 316 ASN A C   1 
ATOM 3633 O O   . ASN B 2 202 ? 130.870 104.294 125.343 1.00 76.78  ? 316 ASN A O   1 
ATOM 3634 C CB  . ASN B 2 202 ? 128.253 104.245 124.341 1.00 74.26  ? 316 ASN A CB  1 
ATOM 3635 C CG  . ASN B 2 202 ? 128.260 105.624 123.738 1.00 74.67  ? 316 ASN A CG  1 
ATOM 3636 O OD1 . ASN B 2 202 ? 129.294 106.094 123.272 1.00 75.25  ? 316 ASN A OD1 1 
ATOM 3637 N ND2 . ASN B 2 202 ? 127.108 106.283 123.740 1.00 75.19  ? 316 ASN A ND2 1 
ATOM 3638 N N   . LYS B 2 203 ? 131.205 102.144 124.800 1.00 70.36  ? 317 LYS A N   1 
ATOM 3639 C CA  . LYS B 2 203 ? 132.351 101.986 125.680 1.00 66.93  ? 317 LYS A CA  1 
ATOM 3640 C C   . LYS B 2 203 ? 133.441 101.215 124.954 1.00 68.84  ? 317 LYS A C   1 
ATOM 3641 O O   . LYS B 2 203 ? 133.159 100.251 124.238 1.00 74.19  ? 317 LYS A O   1 
ATOM 3642 C CB  . LYS B 2 203 ? 131.965 101.258 126.974 1.00 69.41  ? 317 LYS A CB  1 
ATOM 3643 C CG  . LYS B 2 203 ? 133.073 101.196 128.010 1.00 70.19  ? 317 LYS A CG  1 
ATOM 3644 C CD  . LYS B 2 203 ? 132.682 100.322 129.186 1.00 66.17  ? 317 LYS A CD  1 
ATOM 3645 C CE  . LYS B 2 203 ? 131.638 100.997 130.052 1.00 67.81  ? 317 LYS A CE  1 
ATOM 3646 N NZ  . LYS B 2 203 ? 131.345 100.201 131.272 1.00 70.65  ? 317 LYS A NZ  1 
ATOM 3647 N N   . GLU B 2 204 ? 134.684 101.650 125.140 1.00 57.07  ? 318 GLU A N   1 
ATOM 3648 C CA  . GLU B 2 204 ? 135.849 100.960 124.607 1.00 57.94  ? 318 GLU A CA  1 
ATOM 3649 C C   . GLU B 2 204 ? 136.834 100.695 125.732 1.00 54.91  ? 318 GLU A C   1 
ATOM 3650 O O   . GLU B 2 204 ? 136.998 101.524 126.632 1.00 59.25  ? 318 GLU A O   1 
ATOM 3651 C CB  . GLU B 2 204 ? 136.532 101.772 123.501 1.00 62.31  ? 318 GLU A CB  1 
ATOM 3652 C CG  . GLU B 2 204 ? 135.941 101.564 122.120 1.00 68.83  ? 318 GLU A CG  1 
ATOM 3653 C CD  . GLU B 2 204 ? 136.878 100.806 121.198 1.00 67.79  ? 318 GLU A CD  1 
ATOM 3654 O OE1 . GLU B 2 204 ? 138.009 100.493 121.624 1.00 60.74  ? 318 GLU A OE1 1 
ATOM 3655 O OE2 . GLU B 2 204 ? 136.482 100.521 120.049 1.00 68.81  ? 318 GLU A OE2 1 
ATOM 3656 N N   . ILE B 2 205 ? 137.486 99.539  125.678 1.00 47.38  ? 319 ILE A N   1 
ATOM 3657 C CA  . ILE B 2 205 ? 138.516 99.164  126.638 1.00 46.39  ? 319 ILE A CA  1 
ATOM 3658 C C   . ILE B 2 205 ? 139.856 99.208  125.919 1.00 53.42  ? 319 ILE A C   1 
ATOM 3659 O O   . ILE B 2 205 ? 140.058 98.501  124.925 1.00 62.06  ? 319 ILE A O   1 
ATOM 3660 C CB  . ILE B 2 205 ? 138.257 97.776  127.241 1.00 39.84  ? 319 ILE A CB  1 
ATOM 3661 C CG1 . ILE B 2 205 ? 136.940 97.770  128.016 1.00 45.85  ? 319 ILE A CG1 1 
ATOM 3662 C CG2 . ILE B 2 205 ? 139.408 97.366  128.140 1.00 41.43  ? 319 ILE A CG2 1 
ATOM 3663 C CD1 . ILE B 2 205 ? 136.561 96.413  128.555 1.00 56.05  ? 319 ILE A CD1 1 
ATOM 3664 N N   . TYR B 2 206 ? 140.767 100.035 126.418 1.00 45.90  ? 320 TYR A N   1 
ATOM 3665 C CA  . TYR B 2 206 ? 142.095 100.180 125.840 1.00 43.68  ? 320 TYR A CA  1 
ATOM 3666 C C   . TYR B 2 206 ? 143.078 99.385  126.687 1.00 47.86  ? 320 TYR A C   1 
ATOM 3667 O O   . TYR B 2 206 ? 143.183 99.609  127.898 1.00 54.93  ? 320 TYR A O   1 
ATOM 3668 C CB  . TYR B 2 206 ? 142.497 101.651 125.763 1.00 45.29  ? 320 TYR A CB  1 
ATOM 3669 C CG  . TYR B 2 206 ? 141.493 102.502 125.024 1.00 45.70  ? 320 TYR A CG  1 
ATOM 3670 C CD1 . TYR B 2 206 ? 141.568 102.660 123.650 1.00 48.08  ? 320 TYR A CD1 1 
ATOM 3671 C CD2 . TYR B 2 206 ? 140.463 103.138 125.701 1.00 48.28  ? 320 TYR A CD2 1 
ATOM 3672 C CE1 . TYR B 2 206 ? 140.648 103.431 122.971 1.00 47.97  ? 320 TYR A CE1 1 
ATOM 3673 C CE2 . TYR B 2 206 ? 139.540 103.911 125.031 1.00 46.76  ? 320 TYR A CE2 1 
ATOM 3674 C CZ  . TYR B 2 206 ? 139.637 104.055 123.666 1.00 45.92  ? 320 TYR A CZ  1 
ATOM 3675 O OH  . TYR B 2 206 ? 138.719 104.825 122.993 1.00 47.67  ? 320 TYR A OH  1 
ATOM 3676 N N   . CYS B 2 207 ? 143.791 98.462  126.054 1.00 59.40  ? 321 CYS A N   1 
ATOM 3677 C CA  . CYS B 2 207 ? 144.648 97.520  126.753 1.00 58.23  ? 321 CYS A CA  1 
ATOM 3678 C C   . CYS B 2 207 ? 146.114 97.844  126.505 1.00 60.14  ? 321 CYS A C   1 
ATOM 3679 O O   . CYS B 2 207 ? 146.482 98.396  125.464 1.00 62.50  ? 321 CYS A O   1 
ATOM 3680 C CB  . CYS B 2 207 ? 144.351 96.087  126.310 1.00 52.17  ? 321 CYS A CB  1 
ATOM 3681 S SG  . CYS B 2 207 ? 142.606 95.789  125.967 1.00 70.24  ? 321 CYS A SG  1 
ATOM 3682 N N   . HIS B 2 208 ? 146.948 97.494  127.479 1.00 62.08  ? 322 HIS A N   1 
ATOM 3683 C CA  . HIS B 2 208 ? 148.385 97.690  127.382 1.00 62.11  ? 322 HIS A CA  1 
ATOM 3684 C C   . HIS B 2 208 ? 149.049 96.773  128.394 1.00 69.45  ? 322 HIS A C   1 
ATOM 3685 O O   . HIS B 2 208 ? 148.511 96.552  129.481 1.00 74.36  ? 322 HIS A O   1 
ATOM 3686 C CB  . HIS B 2 208 ? 148.772 99.152  127.635 1.00 67.63  ? 322 HIS A CB  1 
ATOM 3687 C CG  . HIS B 2 208 ? 150.227 99.439  127.428 1.00 74.20  ? 322 HIS A CG  1 
ATOM 3688 N ND1 . HIS B 2 208 ? 150.990 100.119 128.353 1.00 74.10  ? 322 HIS A ND1 1 
ATOM 3689 C CD2 . HIS B 2 208 ? 151.058 99.142  126.402 1.00 71.96  ? 322 HIS A CD2 1 
ATOM 3690 C CE1 . HIS B 2 208 ? 152.228 100.227 127.905 1.00 67.01  ? 322 HIS A CE1 1 
ATOM 3691 N NE2 . HIS B 2 208 ? 152.296 99.642  126.723 1.00 67.39  ? 322 HIS A NE2 1 
ATOM 3692 N N   . MET B 2 209 ? 150.209 96.238  128.031 1.00 81.55  ? 323 MET A N   1 
ATOM 3693 C CA  . MET B 2 209 ? 150.938 95.298  128.871 1.00 82.89  ? 323 MET A CA  1 
ATOM 3694 C C   . MET B 2 209 ? 152.174 95.999  129.415 1.00 84.41  ? 323 MET A C   1 
ATOM 3695 O O   . MET B 2 209 ? 153.007 96.483  128.642 1.00 87.95  ? 323 MET A O   1 
ATOM 3696 C CB  . MET B 2 209 ? 151.314 94.049  128.079 1.00 85.57  ? 323 MET A CB  1 
ATOM 3697 C CG  . MET B 2 209 ? 150.109 93.270  127.589 1.00 85.63  ? 323 MET A CG  1 
ATOM 3698 S SD  . MET B 2 209 ? 150.339 91.486  127.570 1.00 92.56  ? 323 MET A SD  1 
ATOM 3699 C CE  . MET B 2 209 ? 148.631 90.954  127.545 1.00 86.29  ? 323 MET A CE  1 
ATOM 3700 N N   . THR B 2 210 ? 152.293 96.049  130.738 1.00 91.27  ? 324 THR A N   1 
ATOM 3701 C CA  . THR B 2 210 ? 153.309 96.850  131.400 1.00 94.61  ? 324 THR A CA  1 
ATOM 3702 C C   . THR B 2 210 ? 154.169 95.982  132.308 1.00 98.81  ? 324 THR A C   1 
ATOM 3703 O O   . THR B 2 210 ? 153.692 95.014  132.909 1.00 98.28  ? 324 THR A O   1 
ATOM 3704 C CB  . THR B 2 210 ? 152.672 97.979  132.222 1.00 92.31  ? 324 THR A CB  1 
ATOM 3705 O OG1 . THR B 2 210 ? 151.638 98.606  131.454 1.00 88.37  ? 324 THR A OG1 1 
ATOM 3706 C CG2 . THR B 2 210 ? 153.710 99.023  132.595 1.00 95.66  ? 324 THR A CG2 1 
ATOM 3707 N N   . CYS B 2 211 ? 155.446 96.339  132.395 1.00 117.63 ? 325 CYS A N   1 
ATOM 3708 C CA  . CYS B 2 211 ? 156.393 95.738  133.320 1.00 116.90 ? 325 CYS A CA  1 
ATOM 3709 C C   . CYS B 2 211 ? 156.808 96.768  134.362 1.00 114.64 ? 325 CYS A C   1 
ATOM 3710 O O   . CYS B 2 211 ? 156.428 97.940  134.300 1.00 114.03 ? 325 CYS A O   1 
ATOM 3711 C CB  . CYS B 2 211 ? 157.621 95.201  132.574 1.00 115.03 ? 325 CYS A CB  1 
ATOM 3712 S SG  . CYS B 2 211 ? 158.935 94.580  133.647 1.00 119.08 ? 325 CYS A SG  1 
ATOM 3713 N N   . ALA B 2 212 ? 157.597 96.312  135.337 1.00 120.66 ? 326 ALA A N   1 
ATOM 3714 C CA  . ALA B 2 212 ? 158.083 97.219  136.371 1.00 121.14 ? 326 ALA A CA  1 
ATOM 3715 C C   . ALA B 2 212 ? 158.989 98.294  135.784 1.00 122.71 ? 326 ALA A C   1 
ATOM 3716 O O   . ALA B 2 212 ? 158.899 99.468  136.162 1.00 123.16 ? 326 ALA A O   1 
ATOM 3717 C CB  . ALA B 2 212 ? 158.814 96.433  137.459 1.00 120.50 ? 326 ALA A CB  1 
ATOM 3718 N N   . THR B 2 213 ? 159.868 97.913  134.858 1.00 127.13 ? 327 THR A N   1 
ATOM 3719 C CA  . THR B 2 213 ? 160.825 98.845  134.261 1.00 126.93 ? 327 THR A CA  1 
ATOM 3720 C C   . THR B 2 213 ? 160.284 99.420  132.949 1.00 126.40 ? 327 THR A C   1 
ATOM 3721 O O   . THR B 2 213 ? 160.895 99.318  131.886 1.00 125.94 ? 327 THR A O   1 
ATOM 3722 C CB  . THR B 2 213 ? 162.169 98.157  134.048 1.00 127.11 ? 327 THR A CB  1 
ATOM 3723 O OG1 . THR B 2 213 ? 162.041 97.164  133.022 1.00 126.08 ? 327 THR A OG1 1 
ATOM 3724 C CG2 . THR B 2 213 ? 162.634 97.491  135.334 1.00 126.23 ? 327 THR A CG2 1 
ATOM 3725 N N   . ASP B 2 214 ? 159.108 100.034 133.042 1.00 118.93 ? 328 ASP A N   1 
ATOM 3726 C CA  . ASP B 2 214 ? 158.478 100.702 131.912 1.00 117.44 ? 328 ASP A CA  1 
ATOM 3727 C C   . ASP B 2 214 ? 158.245 102.167 132.251 1.00 116.97 ? 328 ASP A C   1 
ATOM 3728 O O   . ASP B 2 214 ? 157.804 102.497 133.356 1.00 117.41 ? 328 ASP A O   1 
ATOM 3729 C CB  . ASP B 2 214 ? 157.154 100.031 131.532 1.00 116.44 ? 328 ASP A CB  1 
ATOM 3730 C CG  . ASP B 2 214 ? 157.357 98.744  130.755 1.00 118.78 ? 328 ASP A CG  1 
ATOM 3731 O OD1 . ASP B 2 214 ? 158.391 98.621  130.067 1.00 121.65 ? 328 ASP A OD1 1 
ATOM 3732 O OD2 . ASP B 2 214 ? 156.480 97.858  130.828 1.00 117.90 ? 328 ASP A OD2 1 
ATOM 3733 N N   . THR B 2 215 ? 158.548 103.045 131.292 1.00 107.30 ? 329 THR A N   1 
ATOM 3734 C CA  . THR B 2 215 ? 158.458 104.482 131.502 1.00 107.77 ? 329 THR A CA  1 
ATOM 3735 C C   . THR B 2 215 ? 157.437 105.179 130.615 1.00 106.76 ? 329 THR A C   1 
ATOM 3736 O O   . THR B 2 215 ? 157.051 106.311 130.924 1.00 105.85 ? 329 THR A O   1 
ATOM 3737 C CB  . THR B 2 215 ? 159.827 105.142 131.280 1.00 107.02 ? 329 THR A CB  1 
ATOM 3738 O OG1 . THR B 2 215 ? 159.711 106.560 131.453 1.00 105.70 ? 329 THR A OG1 1 
ATOM 3739 C CG2 . THR B 2 215 ? 160.338 104.845 129.879 1.00 106.07 ? 329 THR A CG2 1 
ATOM 3740 N N   . ASN B 2 216 ? 156.996 104.546 129.529 1.00 92.88  ? 330 ASN A N   1 
ATOM 3741 C CA  . ASN B 2 216 ? 156.096 105.175 128.572 1.00 89.44  ? 330 ASN A CA  1 
ATOM 3742 C C   . ASN B 2 216 ? 154.620 105.050 128.954 1.00 89.09  ? 330 ASN A C   1 
ATOM 3743 O O   . ASN B 2 216 ? 153.752 105.239 128.092 1.00 85.60  ? 330 ASN A O   1 
ATOM 3744 C CB  . ASN B 2 216 ? 156.341 104.598 127.173 1.00 89.32  ? 330 ASN A CB  1 
ATOM 3745 C CG  . ASN B 2 216 ? 155.573 103.315 126.921 1.00 91.82  ? 330 ASN A CG  1 
ATOM 3746 O OD1 . ASN B 2 216 ? 155.559 102.411 127.756 1.00 92.72  ? 330 ASN A OD1 1 
ATOM 3747 N ND2 . ASN B 2 216 ? 154.926 103.232 125.765 1.00 89.90  ? 330 ASN A ND2 1 
ATOM 3748 N N   . ASN B 2 217 ? 154.316 104.759 130.223 1.00 84.86  ? 331 ASN A N   1 
ATOM 3749 C CA  . ASN B 2 217 ? 152.922 104.684 130.652 1.00 79.01  ? 331 ASN A CA  1 
ATOM 3750 C C   . ASN B 2 217 ? 152.208 106.016 130.473 1.00 82.45  ? 331 ASN A C   1 
ATOM 3751 O O   . ASN B 2 217 ? 151.013 106.040 130.152 1.00 87.53  ? 331 ASN A O   1 
ATOM 3752 C CB  . ASN B 2 217 ? 152.835 104.237 132.111 1.00 77.24  ? 331 ASN A CB  1 
ATOM 3753 C CG  . ASN B 2 217 ? 153.268 102.801 132.311 1.00 80.88  ? 331 ASN A CG  1 
ATOM 3754 O OD1 . ASN B 2 217 ? 152.485 101.968 132.762 1.00 85.91  ? 331 ASN A OD1 1 
ATOM 3755 N ND2 . ASN B 2 217 ? 154.520 102.504 131.987 1.00 84.07  ? 331 ASN A ND2 1 
ATOM 3756 N N   . ALA B 2 218 ? 152.915 107.129 130.676 1.00 69.98  ? 332 ALA A N   1 
ATOM 3757 C CA  . ALA B 2 218 ? 152.308 108.439 130.471 1.00 71.10  ? 332 ALA A CA  1 
ATOM 3758 C C   . ALA B 2 218 ? 151.857 108.615 129.028 1.00 70.50  ? 332 ALA A C   1 
ATOM 3759 O O   . ALA B 2 218 ? 150.774 109.150 128.767 1.00 68.02  ? 332 ALA A O   1 
ATOM 3760 C CB  . ALA B 2 218 ? 153.292 109.539 130.865 1.00 69.46  ? 332 ALA A CB  1 
ATOM 3761 N N   . GLN B 2 219 ? 152.676 108.166 128.075 1.00 62.53  ? 333 GLN A N   1 
ATOM 3762 C CA  . GLN B 2 219 ? 152.311 108.276 126.667 1.00 59.43  ? 333 GLN A CA  1 
ATOM 3763 C C   . GLN B 2 219 ? 151.068 107.450 126.351 1.00 56.36  ? 333 GLN A C   1 
ATOM 3764 O O   . GLN B 2 219 ? 150.173 107.911 125.631 1.00 60.21  ? 333 GLN A O   1 
ATOM 3765 C CB  . GLN B 2 219 ? 153.496 107.848 125.800 1.00 65.61  ? 333 GLN A CB  1 
ATOM 3766 C CG  . GLN B 2 219 ? 153.649 108.627 124.508 1.00 66.36  ? 333 GLN A CG  1 
ATOM 3767 C CD  . GLN B 2 219 ? 152.782 108.083 123.399 1.00 68.67  ? 333 GLN A CD  1 
ATOM 3768 O OE1 . GLN B 2 219 ? 152.561 106.876 123.309 1.00 64.27  ? 333 GLN A OE1 1 
ATOM 3769 N NE2 . GLN B 2 219 ? 152.282 108.969 122.545 1.00 68.55  ? 333 GLN A NE2 1 
ATOM 3770 N N   . VAL B 2 220 ? 150.992 106.230 126.888 1.00 58.06  ? 334 VAL A N   1 
ATOM 3771 C CA  . VAL B 2 220 ? 149.829 105.377 126.653 1.00 59.55  ? 334 VAL A CA  1 
ATOM 3772 C C   . VAL B 2 220 ? 148.576 106.008 127.245 1.00 54.24  ? 334 VAL A C   1 
ATOM 3773 O O   . VAL B 2 220 ? 147.506 106.012 126.619 1.00 56.49  ? 334 VAL A O   1 
ATOM 3774 C CB  . VAL B 2 220 ? 150.078 103.969 127.223 1.00 56.83  ? 334 VAL A CB  1 
ATOM 3775 C CG1 . VAL B 2 220 ? 148.783 103.178 127.279 1.00 56.77  ? 334 VAL A CG1 1 
ATOM 3776 C CG2 . VAL B 2 220 ? 151.119 103.239 126.394 1.00 57.98  ? 334 VAL A CG2 1 
ATOM 3777 N N   . ILE B 2 221 ? 148.685 106.544 128.464 1.00 49.30  ? 335 ILE A N   1 
ATOM 3778 C CA  . ILE B 2 221 ? 147.547 107.217 129.081 1.00 46.33  ? 335 ILE A CA  1 
ATOM 3779 C C   . ILE B 2 221 ? 147.117 108.409 128.238 1.00 47.92  ? 335 ILE A C   1 
ATOM 3780 O O   . ILE B 2 221 ? 145.920 108.663 128.064 1.00 58.69  ? 335 ILE A O   1 
ATOM 3781 C CB  . ILE B 2 221 ? 147.885 107.637 130.524 1.00 45.17  ? 335 ILE A CB  1 
ATOM 3782 C CG1 . ILE B 2 221 ? 148.159 106.410 131.390 1.00 50.96  ? 335 ILE A CG1 1 
ATOM 3783 C CG2 . ILE B 2 221 ? 146.752 108.449 131.121 1.00 42.20  ? 335 ILE A CG2 1 
ATOM 3784 C CD1 . ILE B 2 221 ? 148.633 106.746 132.783 1.00 51.40  ? 335 ILE A CD1 1 
ATOM 3785 N N   . PHE B 2 222 ? 148.084 109.157 127.704 1.00 47.21  ? 336 PHE A N   1 
ATOM 3786 C CA  . PHE B 2 222 ? 147.752 110.312 126.877 1.00 48.63  ? 336 PHE A CA  1 
ATOM 3787 C C   . PHE B 2 222 ? 147.003 109.895 125.618 1.00 47.68  ? 336 PHE A C   1 
ATOM 3788 O O   . PHE B 2 222 ? 146.010 110.529 125.242 1.00 46.04  ? 336 PHE A O   1 
ATOM 3789 C CB  . PHE B 2 222 ? 149.022 111.079 126.513 1.00 54.53  ? 336 PHE A CB  1 
ATOM 3790 C CG  . PHE B 2 222 ? 148.773 112.290 125.666 1.00 48.25  ? 336 PHE A CG  1 
ATOM 3791 C CD1 . PHE B 2 222 ? 148.093 113.380 126.178 1.00 47.60  ? 336 PHE A CD1 1 
ATOM 3792 C CD2 . PHE B 2 222 ? 149.215 112.337 124.356 1.00 54.31  ? 336 PHE A CD2 1 
ATOM 3793 C CE1 . PHE B 2 222 ? 147.862 114.496 125.402 1.00 52.46  ? 336 PHE A CE1 1 
ATOM 3794 C CE2 . PHE B 2 222 ? 148.987 113.451 123.573 1.00 60.46  ? 336 PHE A CE2 1 
ATOM 3795 C CZ  . PHE B 2 222 ? 148.309 114.532 124.097 1.00 59.59  ? 336 PHE A CZ  1 
ATOM 3796 N N   . ASP B 2 223 ? 147.464 108.832 124.951 1.00 55.68  ? 337 ASP A N   1 
ATOM 3797 C CA  . ASP B 2 223 ? 146.767 108.370 123.752 1.00 50.92  ? 337 ASP A CA  1 
ATOM 3798 C C   . ASP B 2 223 ? 145.359 107.891 124.079 1.00 53.20  ? 337 ASP A C   1 
ATOM 3799 O O   . ASP B 2 223 ? 144.405 108.203 123.356 1.00 50.76  ? 337 ASP A O   1 
ATOM 3800 C CB  . ASP B 2 223 ? 147.546 107.256 123.054 1.00 48.24  ? 337 ASP A CB  1 
ATOM 3801 C CG  . ASP B 2 223 ? 148.988 107.620 122.795 1.00 57.95  ? 337 ASP A CG  1 
ATOM 3802 O OD1 . ASP B 2 223 ? 149.237 108.656 122.145 1.00 53.52  ? 337 ASP A OD1 1 
ATOM 3803 O OD2 . ASP B 2 223 ? 149.870 106.842 123.206 1.00 57.69  ? 337 ASP A OD2 1 
ATOM 3804 N N   . ALA B 2 224 ? 145.205 107.130 125.164 1.00 45.85  ? 338 ALA A N   1 
ATOM 3805 C CA  . ALA B 2 224 ? 143.877 106.648 125.529 1.00 34.94  ? 338 ALA A CA  1 
ATOM 3806 C C   . ALA B 2 224 ? 142.942 107.806 125.857 1.00 37.81  ? 338 ALA A C   1 
ATOM 3807 O O   . ALA B 2 224 ? 141.783 107.821 125.426 1.00 47.57  ? 338 ALA A O   1 
ATOM 3808 C CB  . ALA B 2 224 ? 143.976 105.682 126.708 1.00 38.10  ? 338 ALA A CB  1 
ATOM 3809 N N   . VAL B 2 225 ? 143.434 108.796 126.603 1.00 32.65  ? 339 VAL A N   1 
ATOM 3810 C CA  . VAL B 2 225 ? 142.598 109.926 126.990 1.00 28.18  ? 339 VAL A CA  1 
ATOM 3811 C C   . VAL B 2 225 ? 142.216 110.759 125.773 1.00 47.29  ? 339 VAL A C   1 
ATOM 3812 O O   . VAL B 2 225 ? 141.066 111.197 125.645 1.00 53.28  ? 339 VAL A O   1 
ATOM 3813 C CB  . VAL B 2 225 ? 143.311 110.769 128.063 1.00 32.20  ? 339 VAL A CB  1 
ATOM 3814 C CG1 . VAL B 2 225 ? 142.660 112.131 128.192 1.00 42.12  ? 339 VAL A CG1 1 
ATOM 3815 C CG2 . VAL B 2 225 ? 143.284 110.045 129.396 1.00 33.31  ? 339 VAL A CG2 1 
ATOM 3816 N N   . THR B 2 226 ? 143.161 110.994 124.857 1.00 48.76  ? 340 THR A N   1 
ATOM 3817 C CA  . THR B 2 226 ? 142.825 111.774 123.670 1.00 42.24  ? 340 THR A CA  1 
ATOM 3818 C C   . THR B 2 226 ? 141.851 111.018 122.772 1.00 37.54  ? 340 THR A C   1 
ATOM 3819 O O   . THR B 2 226 ? 140.957 111.626 122.177 1.00 38.51  ? 340 THR A O   1 
ATOM 3820 C CB  . THR B 2 226 ? 144.091 112.186 122.908 1.00 37.69  ? 340 THR A CB  1 
ATOM 3821 O OG1 . THR B 2 226 ? 143.763 113.199 121.950 1.00 37.22  ? 340 THR A OG1 1 
ATOM 3822 C CG2 . THR B 2 226 ? 144.728 111.017 122.185 1.00 37.25  ? 340 THR A CG2 1 
ATOM 3823 N N   . ASP B 2 227 ? 141.977 109.690 122.690 1.00 43.40  ? 341 ASP A N   1 
ATOM 3824 C CA  . ASP B 2 227 ? 141.016 108.899 121.928 1.00 43.34  ? 341 ASP A CA  1 
ATOM 3825 C C   . ASP B 2 227 ? 139.625 108.998 122.549 1.00 37.31  ? 341 ASP A C   1 
ATOM 3826 O O   . ASP B 2 227 ? 138.625 109.169 121.837 1.00 37.62  ? 341 ASP A O   1 
ATOM 3827 C CB  . ASP B 2 227 ? 141.523 107.451 121.854 1.00 47.86  ? 341 ASP A CB  1 
ATOM 3828 C CG  . ASP B 2 227 ? 140.557 106.484 121.169 1.00 53.32  ? 341 ASP A CG  1 
ATOM 3829 O OD1 . ASP B 2 227 ? 139.341 106.733 121.083 1.00 52.67  ? 341 ASP A OD1 1 
ATOM 3830 O OD2 . ASP B 2 227 ? 141.045 105.439 120.691 1.00 59.07  ? 341 ASP A OD2 1 
ATOM 3831 N N   . ILE B 2 228 ? 139.546 108.916 123.878 1.00 32.88  ? 342 ILE A N   1 
ATOM 3832 C CA  . ILE B 2 228 ? 138.259 109.027 124.560 1.00 36.46  ? 342 ILE A CA  1 
ATOM 3833 C C   . ILE B 2 228 ? 137.646 110.403 124.326 1.00 42.14  ? 342 ILE A C   1 
ATOM 3834 O O   . ILE B 2 228 ? 136.435 110.532 124.099 1.00 47.39  ? 342 ILE A O   1 
ATOM 3835 C CB  . ILE B 2 228 ? 138.429 108.721 126.058 1.00 35.32  ? 342 ILE A CB  1 
ATOM 3836 C CG1 . ILE B 2 228 ? 138.764 107.243 126.252 1.00 30.49  ? 342 ILE A CG1 1 
ATOM 3837 C CG2 . ILE B 2 228 ? 137.174 109.083 126.829 1.00 36.24  ? 342 ILE A CG2 1 
ATOM 3838 C CD1 . ILE B 2 228 ? 139.414 106.935 127.566 1.00 26.46  ? 342 ILE A CD1 1 
ATOM 3839 N N   . ILE B 2 229 ? 138.469 111.452 124.381 1.00 36.77  ? 343 ILE A N   1 
ATOM 3840 C CA  . ILE B 2 229 ? 137.973 112.805 124.147 1.00 30.12  ? 343 ILE A CA  1 
ATOM 3841 C C   . ILE B 2 229 ? 137.472 112.954 122.714 1.00 42.44  ? 343 ILE A C   1 
ATOM 3842 O O   . ILE B 2 229 ? 136.435 113.582 122.467 1.00 46.59  ? 343 ILE A O   1 
ATOM 3843 C CB  . ILE B 2 229 ? 139.065 113.837 124.485 1.00 31.96  ? 343 ILE A CB  1 
ATOM 3844 C CG1 . ILE B 2 229 ? 139.171 114.012 126.000 1.00 32.89  ? 343 ILE A CG1 1 
ATOM 3845 C CG2 . ILE B 2 229 ? 138.779 115.172 123.820 1.00 44.45  ? 343 ILE A CG2 1 
ATOM 3846 C CD1 . ILE B 2 229 ? 140.479 114.606 126.453 1.00 44.16  ? 343 ILE A CD1 1 
ATOM 3847 N N   . ILE B 2 230 ? 138.196 112.380 121.748 1.00 47.28  ? 344 ILE A N   1 
ATOM 3848 C CA  . ILE B 2 230 ? 137.748 112.418 120.357 1.00 33.61  ? 344 ILE A CA  1 
ATOM 3849 C C   . ILE B 2 230 ? 136.390 111.745 120.220 1.00 36.47  ? 344 ILE A C   1 
ATOM 3850 O O   . ILE B 2 230 ? 135.492 112.255 119.544 1.00 39.64  ? 344 ILE A O   1 
ATOM 3851 C CB  . ILE B 2 230 ? 138.788 111.764 119.427 1.00 39.81  ? 344 ILE A CB  1 
ATOM 3852 C CG1 . ILE B 2 230 ? 140.111 112.526 119.455 1.00 37.41  ? 344 ILE A CG1 1 
ATOM 3853 C CG2 . ILE B 2 230 ? 138.259 111.685 118.005 1.00 42.18  ? 344 ILE A CG2 1 
ATOM 3854 C CD1 . ILE B 2 230 ? 139.987 113.961 119.081 1.00 42.40  ? 344 ILE A CD1 1 
ATOM 3855 N N   . ALA B 2 231 ? 136.224 110.581 120.854 1.00 38.09  ? 345 ALA A N   1 
ATOM 3856 C CA  . ALA B 2 231 ? 134.951 109.869 120.756 1.00 35.61  ? 345 ALA A CA  1 
ATOM 3857 C C   . ALA B 2 231 ? 133.813 110.661 121.393 1.00 39.65  ? 345 ALA A C   1 
ATOM 3858 O O   . ALA B 2 231 ? 132.707 110.725 120.841 1.00 50.90  ? 345 ALA A O   1 
ATOM 3859 C CB  . ALA B 2 231 ? 135.069 108.488 121.398 1.00 42.20  ? 345 ALA A CB  1 
ATOM 3860 N N   . ASN B 2 232 ? 134.062 111.269 122.555 1.00 38.25  ? 346 ASN A N   1 
ATOM 3861 C CA  . ASN B 2 232 ? 133.024 112.068 123.202 1.00 34.56  ? 346 ASN A CA  1 
ATOM 3862 C C   . ASN B 2 232 ? 132.639 113.274 122.354 1.00 41.66  ? 346 ASN A C   1 
ATOM 3863 O O   . ASN B 2 232 ? 131.453 113.601 122.226 1.00 39.18  ? 346 ASN A O   1 
ATOM 3864 C CB  . ASN B 2 232 ? 133.486 112.515 124.588 1.00 43.63  ? 346 ASN A CB  1 
ATOM 3865 C CG  . ASN B 2 232 ? 133.882 111.353 125.473 1.00 50.12  ? 346 ASN A CG  1 
ATOM 3866 O OD1 . ASN B 2 232 ? 133.310 110.267 125.385 1.00 56.96  ? 346 ASN A OD1 1 
ATOM 3867 N ND2 . ASN B 2 232 ? 134.865 111.577 126.337 1.00 50.03  ? 346 ASN A ND2 1 
ATOM 3868 N N   . ASN B 2 233 ? 133.630 113.954 121.771 1.00 49.77  ? 347 ASN A N   1 
ATOM 3869 C CA  . ASN B 2 233 ? 133.335 115.090 120.905 1.00 47.70  ? 347 ASN A CA  1 
ATOM 3870 C C   . ASN B 2 233 ? 132.577 114.647 119.661 1.00 55.84  ? 347 ASN A C   1 
ATOM 3871 O O   . ASN B 2 233 ? 131.678 115.352 119.187 1.00 64.00  ? 347 ASN A O   1 
ATOM 3872 C CB  . ASN B 2 233 ? 134.627 115.808 120.523 1.00 44.63  ? 347 ASN A CB  1 
ATOM 3873 C CG  . ASN B 2 233 ? 135.120 116.734 121.612 1.00 47.17  ? 347 ASN A CG  1 
ATOM 3874 O OD1 . ASN B 2 233 ? 134.452 116.929 122.626 1.00 45.83  ? 347 ASN A OD1 1 
ATOM 3875 N ND2 . ASN B 2 233 ? 136.297 117.311 121.409 1.00 51.01  ? 347 ASN A ND2 1 
ATOM 3876 N N   . LEU B 2 234 ? 132.934 113.484 119.114 1.00 56.06  ? 348 LEU A N   1 
ATOM 3877 C CA  . LEU B 2 234 ? 132.203 112.927 117.983 1.00 45.35  ? 348 LEU A CA  1 
ATOM 3878 C C   . LEU B 2 234 ? 130.743 112.700 118.335 1.00 41.42  ? 348 LEU A C   1 
ATOM 3879 O O   . LEU B 2 234 ? 129.846 113.022 117.549 1.00 56.47  ? 348 LEU A O   1 
ATOM 3880 C CB  . LEU B 2 234 ? 132.852 111.615 117.549 1.00 47.87  ? 348 LEU A CB  1 
ATOM 3881 C CG  . LEU B 2 234 ? 132.712 111.183 116.095 1.00 55.85  ? 348 LEU A CG  1 
ATOM 3882 C CD1 . LEU B 2 234 ? 133.784 111.844 115.265 1.00 58.44  ? 348 LEU A CD1 1 
ATOM 3883 C CD2 . LEU B 2 234 ? 132.804 109.671 115.993 1.00 52.81  ? 348 LEU A CD2 1 
ATOM 3884 N N   . ARG B 2 235 ? 130.486 112.136 119.514 1.00 49.50  ? 349 ARG A N   1 
ATOM 3885 C CA  . ARG B 2 235 ? 129.108 111.902 119.929 1.00 57.26  ? 349 ARG A CA  1 
ATOM 3886 C C   . ARG B 2 235 ? 128.364 113.216 120.130 1.00 62.05  ? 349 ARG A C   1 
ATOM 3887 O O   . ARG B 2 235 ? 127.189 113.334 119.761 1.00 66.43  ? 349 ARG A O   1 
ATOM 3888 C CB  . ARG B 2 235 ? 129.083 111.075 121.209 1.00 64.70  ? 349 ARG A CB  1 
ATOM 3889 C CG  . ARG B 2 235 ? 127.738 110.466 121.527 1.00 57.14  ? 349 ARG A CG  1 
ATOM 3890 C CD  . ARG B 2 235 ? 127.969 109.082 122.078 1.00 59.54  ? 349 ARG A CD  1 
ATOM 3891 N NE  . ARG B 2 235 ? 128.504 108.205 121.044 1.00 65.48  ? 349 ARG A NE  1 
ATOM 3892 C CZ  . ARG B 2 235 ? 129.747 107.745 121.032 1.00 66.52  ? 349 ARG A CZ  1 
ATOM 3893 N NH1 . ARG B 2 235 ? 130.609 108.061 121.985 1.00 62.15  ? 349 ARG A NH1 1 
ATOM 3894 N NH2 . ARG B 2 235 ? 130.135 106.942 120.047 1.00 63.14  ? 349 ARG A NH2 1 
ATOM 3895 N N   . GLY B 2 236 ? 129.029 114.209 120.722 1.00 58.17  ? 350 GLY A N   1 
ATOM 3896 C CA  . GLY B 2 236 ? 128.379 115.489 120.947 1.00 59.88  ? 350 GLY A CA  1 
ATOM 3897 C C   . GLY B 2 236 ? 128.033 116.209 119.658 1.00 61.29  ? 350 GLY A C   1 
ATOM 3898 O O   . GLY B 2 236 ? 126.958 116.801 119.534 1.00 65.92  ? 350 GLY A O   1 
ATOM 3899 N N   . CYS B 2 237 ? 128.937 116.166 118.677 1.00 62.17  ? 351 CYS A N   1 
ATOM 3900 C CA  . CYS B 2 237 ? 128.718 116.850 117.409 1.00 53.18  ? 351 CYS A CA  1 
ATOM 3901 C C   . CYS B 2 237 ? 127.619 116.212 116.572 1.00 62.06  ? 351 CYS A C   1 
ATOM 3902 O O   . CYS B 2 237 ? 127.191 116.815 115.583 1.00 65.11  ? 351 CYS A O   1 
ATOM 3903 C CB  . CYS B 2 237 ? 130.018 116.886 116.606 1.00 52.90  ? 351 CYS A CB  1 
ATOM 3904 S SG  . CYS B 2 237 ? 131.258 118.023 117.253 1.00 77.76  ? 351 CYS A SG  1 
ATOM 3905 N N   . GLY B 2 238 ? 127.155 115.019 116.936 1.00 67.74  ? 352 GLY A N   1 
ATOM 3906 C CA  . GLY B 2 238 ? 126.117 114.346 116.188 1.00 69.64  ? 352 GLY A CA  1 
ATOM 3907 C C   . GLY B 2 238 ? 126.592 113.541 115.000 1.00 67.92  ? 352 GLY A C   1 
ATOM 3908 O O   . GLY B 2 238 ? 125.753 113.007 114.264 1.00 67.98  ? 352 GLY A O   1 
ATOM 3909 N N   . LEU B 2 239 ? 127.904 113.441 114.780 1.00 68.16  ? 353 LEU A N   1 
ATOM 3910 C CA  . LEU B 2 239 ? 128.404 112.654 113.658 1.00 66.81  ? 353 LEU A CA  1 
ATOM 3911 C C   . LEU B 2 239 ? 128.041 111.183 113.811 1.00 71.05  ? 353 LEU A C   1 
ATOM 3912 O O   . LEU B 2 239 ? 127.660 110.525 112.836 1.00 79.98  ? 353 LEU A O   1 
ATOM 3913 C CB  . LEU B 2 239 ? 129.917 112.826 113.529 1.00 63.55  ? 353 LEU A CB  1 
ATOM 3914 C CG  . LEU B 2 239 ? 130.384 114.111 112.846 1.00 68.90  ? 353 LEU A CG  1 
ATOM 3915 C CD1 . LEU B 2 239 ? 131.893 114.134 112.728 1.00 67.10  ? 353 LEU A CD1 1 
ATOM 3916 C CD2 . LEU B 2 239 ? 129.741 114.254 111.479 1.00 69.66  ? 353 LEU A CD2 1 
ATOM 3917 N N   . TYR B 2 240 ? 128.150 110.651 115.024 1.00 88.86  ? 354 TYR A N   1 
ATOM 3918 C CA  . TYR B 2 240 ? 127.773 109.268 115.288 1.00 91.31  ? 354 TYR A CA  1 
ATOM 3919 C C   . TYR B 2 240 ? 126.551 109.210 116.200 1.00 91.50  ? 354 TYR A C   1 
ATOM 3920 O O   . TYR B 2 240 ? 125.882 108.183 116.308 1.00 91.76  ? 354 TYR A O   1 
ATOM 3921 C CB  . TYR B 2 240 ? 128.936 108.500 115.918 1.00 87.60  ? 354 TYR A CB  1 
ATOM 3922 C CG  . TYR B 2 240 ? 128.647 107.034 116.143 1.00 89.31  ? 354 TYR A CG  1 
ATOM 3923 C CD1 . TYR B 2 240 ? 128.292 106.206 115.089 1.00 90.02  ? 354 TYR A CD1 1 
ATOM 3924 C CD2 . TYR B 2 240 ? 128.713 106.483 117.412 1.00 92.26  ? 354 TYR A CD2 1 
ATOM 3925 C CE1 . TYR B 2 240 ? 128.024 104.864 115.293 1.00 93.60  ? 354 TYR A CE1 1 
ATOM 3926 C CE2 . TYR B 2 240 ? 128.447 105.144 117.628 1.00 95.41  ? 354 TYR A CE2 1 
ATOM 3927 C CZ  . TYR B 2 240 ? 128.102 104.339 116.565 1.00 95.19  ? 354 TYR A CZ  1 
ATOM 3928 O OH  . TYR B 2 240 ? 127.834 103.006 116.774 1.00 90.18  ? 354 TYR A OH  1 
ATOM 3929 O OXT . TYR B 2 240 ? 126.204 110.194 116.852 1.00 94.01  ? 354 TYR A OXT 1 
ATOM 3930 N N   . ASP C 3 15  ? 124.932 81.478  172.369 1.00 114.44 ? 5   ASP B N   1 
ATOM 3931 C CA  . ASP C 3 15  ? 123.783 80.781  171.803 1.00 116.54 ? 5   ASP B CA  1 
ATOM 3932 C C   . ASP C 3 15  ? 122.493 81.198  172.501 1.00 117.36 ? 5   ASP B C   1 
ATOM 3933 O O   . ASP C 3 15  ? 121.506 81.541  171.850 1.00 116.53 ? 5   ASP B O   1 
ATOM 3934 C CB  . ASP C 3 15  ? 123.971 79.266  171.902 1.00 114.73 ? 5   ASP B CB  1 
ATOM 3935 N N   . GLN C 3 16  ? 122.508 81.161  173.836 1.00 120.57 ? 6   GLN B N   1 
ATOM 3936 C CA  . GLN C 3 16  ? 121.345 81.596  174.601 1.00 119.75 ? 6   GLN B CA  1 
ATOM 3937 C C   . GLN C 3 16  ? 121.079 83.085  174.418 1.00 120.02 ? 6   GLN B C   1 
ATOM 3938 O O   . GLN C 3 16  ? 119.922 83.518  174.468 1.00 118.50 ? 6   GLN B O   1 
ATOM 3939 C CB  . GLN C 3 16  ? 121.535 81.268  176.082 1.00 117.00 ? 6   GLN B CB  1 
ATOM 3940 N N   . LEU C 3 17  ? 122.133 83.879  174.211 1.00 122.73 ? 7   LEU B N   1 
ATOM 3941 C CA  . LEU C 3 17  ? 121.949 85.308  173.987 1.00 122.00 ? 7   LEU B CA  1 
ATOM 3942 C C   . LEU C 3 17  ? 121.184 85.579  172.698 1.00 120.31 ? 7   LEU B C   1 
ATOM 3943 O O   . LEU C 3 17  ? 120.409 86.538  172.629 1.00 120.55 ? 7   LEU B O   1 
ATOM 3944 C CB  . LEU C 3 17  ? 123.304 86.014  173.960 1.00 121.84 ? 7   LEU B CB  1 
ATOM 3945 N N   . ARG C 3 18  ? 121.385 84.751  171.671 1.00 120.86 ? 8   ARG B N   1 
ATOM 3946 C CA  . ARG C 3 18  ? 120.648 84.927  170.423 1.00 122.69 ? 8   ARG B CA  1 
ATOM 3947 C C   . ARG C 3 18  ? 119.153 84.715  170.634 1.00 122.72 ? 8   ARG B C   1 
ATOM 3948 O O   . ARG C 3 18  ? 118.327 85.499  170.153 1.00 122.16 ? 8   ARG B O   1 
ATOM 3949 C CB  . ARG C 3 18  ? 121.187 83.971  169.359 1.00 122.84 ? 8   ARG B CB  1 
ATOM 3950 C CG  . ARG C 3 18  ? 122.682 84.098  169.116 1.00 121.31 ? 8   ARG B CG  1 
ATOM 3951 C CD  . ARG C 3 18  ? 123.020 85.403  168.413 1.00 123.51 ? 8   ARG B CD  1 
ATOM 3952 N NE  . ARG C 3 18  ? 124.373 85.859  168.713 1.00 124.28 ? 8   ARG B NE  1 
ATOM 3953 C CZ  . ARG C 3 18  ? 125.478 85.309  168.228 1.00 123.28 ? 8   ARG B CZ  1 
ATOM 3954 N NH1 . ARG C 3 18  ? 125.433 84.277  167.401 1.00 122.22 ? 8   ARG B NH1 1 
ATOM 3955 N NH2 . ARG C 3 18  ? 126.659 85.810  168.579 1.00 123.38 ? 8   ARG B NH2 1 
ATOM 3956 N N   . GLN C 3 19  ? 118.786 83.659  171.365 1.00 125.11 ? 9   GLN B N   1 
ATOM 3957 C CA  . GLN C 3 19  ? 117.377 83.422  171.665 1.00 126.32 ? 9   GLN B CA  1 
ATOM 3958 C C   . GLN C 3 19  ? 116.810 84.506  172.573 1.00 126.99 ? 9   GLN B C   1 
ATOM 3959 O O   . GLN C 3 19  ? 115.640 84.883  172.431 1.00 125.89 ? 9   GLN B O   1 
ATOM 3960 C CB  . GLN C 3 19  ? 117.198 82.045  172.304 1.00 125.40 ? 9   GLN B CB  1 
ATOM 3961 N N   . GLU C 3 20  ? 117.616 85.009  173.510 1.00 126.54 ? 10  GLU B N   1 
ATOM 3962 C CA  . GLU C 3 20  ? 117.172 86.115  174.350 1.00 126.30 ? 10  GLU B CA  1 
ATOM 3963 C C   . GLU C 3 20  ? 116.880 87.354  173.513 1.00 126.15 ? 10  GLU B C   1 
ATOM 3964 O O   . GLU C 3 20  ? 115.859 88.022  173.709 1.00 123.82 ? 10  GLU B O   1 
ATOM 3965 C CB  . GLU C 3 20  ? 118.228 86.411  175.416 1.00 125.97 ? 10  GLU B CB  1 
ATOM 3966 C CG  . GLU C 3 20  ? 117.833 87.478  176.421 1.00 126.28 ? 10  GLU B CG  1 
ATOM 3967 C CD  . GLU C 3 20  ? 119.002 87.926  177.278 1.00 126.76 ? 10  GLU B CD  1 
ATOM 3968 O OE1 . GLU C 3 20  ? 120.130 87.439  177.050 1.00 124.63 ? 10  GLU B OE1 1 
ATOM 3969 O OE2 . GLU C 3 20  ? 118.794 88.763  178.181 1.00 127.70 ? 10  GLU B OE2 1 
ATOM 3970 N N   . ALA C 3 21  ? 117.757 87.663  172.556 1.00 127.16 ? 11  ALA B N   1 
ATOM 3971 C CA  . ALA C 3 21  ? 117.513 88.787  171.660 1.00 124.97 ? 11  ALA B CA  1 
ATOM 3972 C C   . ALA C 3 21  ? 116.271 88.553  170.809 1.00 125.50 ? 11  ALA B C   1 
ATOM 3973 O O   . ALA C 3 21  ? 115.499 89.484  170.554 1.00 127.62 ? 11  ALA B O   1 
ATOM 3974 C CB  . ALA C 3 21  ? 118.735 89.026  170.774 1.00 126.06 ? 11  ALA B CB  1 
ATOM 3975 N N   . GLU C 3 22  ? 116.068 87.315  170.353 1.00 123.80 ? 12  GLU B N   1 
ATOM 3976 C CA  . GLU C 3 22  ? 114.898 87.008  169.536 1.00 125.03 ? 12  GLU B CA  1 
ATOM 3977 C C   . GLU C 3 22  ? 113.606 87.219  170.317 1.00 123.76 ? 12  GLU B C   1 
ATOM 3978 O O   . GLU C 3 22  ? 112.653 87.826  169.812 1.00 121.88 ? 12  GLU B O   1 
ATOM 3979 C CB  . GLU C 3 22  ? 114.985 85.573  169.016 1.00 126.04 ? 12  GLU B CB  1 
ATOM 3980 C CG  . GLU C 3 22  ? 113.977 85.249  167.926 1.00 125.49 ? 12  GLU B CG  1 
ATOM 3981 C CD  . GLU C 3 22  ? 114.325 85.889  166.597 1.00 125.62 ? 12  GLU B CD  1 
ATOM 3982 O OE1 . GLU C 3 22  ? 115.465 86.377  166.445 1.00 125.53 ? 12  GLU B OE1 1 
ATOM 3983 O OE2 . GLU C 3 22  ? 113.455 85.908  165.701 1.00 126.08 ? 12  GLU B OE2 1 
ATOM 3984 N N   . GLN C 3 23  ? 113.555 86.730  171.559 1.00 124.68 ? 13  GLN B N   1 
ATOM 3985 C CA  . GLN C 3 23  ? 112.349 86.927  172.359 1.00 125.80 ? 13  GLN B CA  1 
ATOM 3986 C C   . GLN C 3 23  ? 112.171 88.390  172.745 1.00 125.97 ? 13  GLN B C   1 
ATOM 3987 O O   . GLN C 3 23  ? 111.036 88.862  172.861 1.00 124.55 ? 13  GLN B O   1 
ATOM 3988 C CB  . GLN C 3 23  ? 112.366 86.032  173.602 1.00 125.99 ? 13  GLN B CB  1 
ATOM 3989 C CG  . GLN C 3 23  ? 113.541 86.238  174.538 1.00 125.46 ? 13  GLN B CG  1 
ATOM 3990 C CD  . GLN C 3 23  ? 113.258 87.257  175.627 1.00 126.11 ? 13  GLN B CD  1 
ATOM 3991 O OE1 . GLN C 3 23  ? 112.132 87.733  175.772 1.00 125.47 ? 13  GLN B OE1 1 
ATOM 3992 N NE2 . GLN C 3 23  ? 114.286 87.602  176.395 1.00 124.25 ? 13  GLN B NE2 1 
ATOM 3993 N N   . LEU C 3 24  ? 113.272 89.124  172.935 1.00 122.42 ? 14  LEU B N   1 
ATOM 3994 C CA  . LEU C 3 24  ? 113.169 90.557  173.189 1.00 120.74 ? 14  LEU B CA  1 
ATOM 3995 C C   . LEU C 3 24  ? 112.556 91.287  172.001 1.00 119.18 ? 14  LEU B C   1 
ATOM 3996 O O   . LEU C 3 24  ? 111.673 92.138  172.169 1.00 119.76 ? 14  LEU B O   1 
ATOM 3997 C CB  . LEU C 3 24  ? 114.553 91.120  173.505 1.00 121.12 ? 14  LEU B CB  1 
ATOM 3998 C CG  . LEU C 3 24  ? 115.068 90.838  174.913 1.00 121.79 ? 14  LEU B CG  1 
ATOM 3999 C CD1 . LEU C 3 24  ? 116.537 91.198  175.005 1.00 120.15 ? 14  LEU B CD1 1 
ATOM 4000 C CD2 . LEU C 3 24  ? 114.250 91.603  175.940 1.00 121.48 ? 14  LEU B CD2 1 
ATOM 4001 N N   . LYS C 3 25  ? 113.014 90.964  170.789 1.00 117.30 ? 15  LYS B N   1 
ATOM 4002 C CA  . LYS C 3 25  ? 112.435 91.564  169.592 1.00 118.40 ? 15  LYS B CA  1 
ATOM 4003 C C   . LYS C 3 25  ? 110.969 91.184  169.444 1.00 118.71 ? 15  LYS B C   1 
ATOM 4004 O O   . LYS C 3 25  ? 110.143 92.013  169.047 1.00 119.72 ? 15  LYS B O   1 
ATOM 4005 C CB  . LYS C 3 25  ? 113.225 91.144  168.352 1.00 119.58 ? 15  LYS B CB  1 
ATOM 4006 C CG  . LYS C 3 25  ? 114.669 91.616  168.337 1.00 119.62 ? 15  LYS B CG  1 
ATOM 4007 C CD  . LYS C 3 25  ? 114.761 93.119  168.534 1.00 120.01 ? 15  LYS B CD  1 
ATOM 4008 C CE  . LYS C 3 25  ? 114.221 93.870  167.328 1.00 119.81 ? 15  LYS B CE  1 
ATOM 4009 N NZ  . LYS C 3 25  ? 114.301 95.346  167.512 1.00 116.70 ? 15  LYS B NZ  1 
ATOM 4010 N N   . ASN C 3 26  ? 110.630 89.929  169.750 1.00 120.62 ? 16  ASN B N   1 
ATOM 4011 C CA  . ASN C 3 26  ? 109.236 89.504  169.675 1.00 121.73 ? 16  ASN B CA  1 
ATOM 4012 C C   . ASN C 3 26  ? 108.368 90.283  170.656 1.00 120.05 ? 16  ASN B C   1 
ATOM 4013 O O   . ASN C 3 26  ? 107.262 90.713  170.309 1.00 117.40 ? 16  ASN B O   1 
ATOM 4014 C CB  . ASN C 3 26  ? 109.130 88.002  169.937 1.00 121.90 ? 16  ASN B CB  1 
ATOM 4015 C CG  . ASN C 3 26  ? 109.602 87.172  168.760 1.00 121.84 ? 16  ASN B CG  1 
ATOM 4016 O OD1 . ASN C 3 26  ? 109.336 87.505  167.606 1.00 121.40 ? 16  ASN B OD1 1 
ATOM 4017 N ND2 . ASN C 3 26  ? 110.305 86.083  169.048 1.00 120.90 ? 16  ASN B ND2 1 
ATOM 4018 N N   . GLN C 3 27  ? 108.854 90.479  171.885 1.00 114.65 ? 17  GLN B N   1 
ATOM 4019 C CA  . GLN C 3 27  ? 108.106 91.260  172.866 1.00 113.40 ? 17  GLN B CA  1 
ATOM 4020 C C   . GLN C 3 27  ? 107.938 92.704  172.412 1.00 114.00 ? 17  GLN B C   1 
ATOM 4021 O O   . GLN C 3 27  ? 106.856 93.289  172.555 1.00 113.69 ? 17  GLN B O   1 
ATOM 4022 C CB  . GLN C 3 27  ? 108.809 91.210  174.223 1.00 113.53 ? 17  GLN B CB  1 
ATOM 4023 C CG  . GLN C 3 27  ? 108.207 90.224  175.208 1.00 115.39 ? 17  GLN B CG  1 
ATOM 4024 C CD  . GLN C 3 27  ? 108.929 90.228  176.541 1.00 115.28 ? 17  GLN B CD  1 
ATOM 4025 O OE1 . GLN C 3 27  ? 110.158 90.238  176.594 1.00 113.95 ? 17  GLN B OE1 1 
ATOM 4026 N NE2 . GLN C 3 27  ? 108.165 90.224  177.627 1.00 115.14 ? 17  GLN B NE2 1 
ATOM 4027 N N   . ILE C 3 28  ? 109.004 93.298  171.869 1.00 107.41 ? 18  ILE B N   1 
ATOM 4028 C CA  . ILE C 3 28  ? 108.929 94.681  171.405 1.00 104.57 ? 18  ILE B CA  1 
ATOM 4029 C C   . ILE C 3 28  ? 107.906 94.806  170.283 1.00 104.78 ? 18  ILE B C   1 
ATOM 4030 O O   . ILE C 3 28  ? 107.073 95.719  170.277 1.00 105.98 ? 18  ILE B O   1 
ATOM 4031 C CB  . ILE C 3 28  ? 110.318 95.176  170.964 1.00 104.04 ? 18  ILE B CB  1 
ATOM 4032 C CG1 . ILE C 3 28  ? 111.152 95.579  172.181 1.00 104.64 ? 18  ILE B CG1 1 
ATOM 4033 C CG2 . ILE C 3 28  ? 110.195 96.343  169.997 1.00 104.71 ? 18  ILE B CG2 1 
ATOM 4034 C CD1 . ILE C 3 28  ? 112.572 95.975  171.842 1.00 105.36 ? 18  ILE B CD1 1 
ATOM 4035 N N   . ARG C 3 29  ? 107.944 93.876  169.325 1.00 103.29 ? 19  ARG B N   1 
ATOM 4036 C CA  . ARG C 3 29  ? 106.992 93.906  168.218 1.00 102.40 ? 19  ARG B CA  1 
ATOM 4037 C C   . ARG C 3 29  ? 105.565 93.699  168.708 1.00 104.78 ? 19  ARG B C   1 
ATOM 4038 O O   . ARG C 3 29  ? 104.634 94.347  168.216 1.00 102.28 ? 19  ARG B O   1 
ATOM 4039 C CB  . ARG C 3 29  ? 107.362 92.847  167.180 1.00 102.42 ? 19  ARG B CB  1 
ATOM 4040 N N   . ASP C 3 30  ? 105.370 92.794  169.670 1.00 109.67 ? 20  ASP B N   1 
ATOM 4041 C CA  . ASP C 3 30  ? 104.031 92.540  170.192 1.00 108.08 ? 20  ASP B CA  1 
ATOM 4042 C C   . ASP C 3 30  ? 103.469 93.775  170.885 1.00 107.22 ? 20  ASP B C   1 
ATOM 4043 O O   . ASP C 3 30  ? 102.312 94.151  170.665 1.00 106.82 ? 20  ASP B O   1 
ATOM 4044 C CB  . ASP C 3 30  ? 104.060 91.349  171.149 1.00 108.10 ? 20  ASP B CB  1 
ATOM 4045 C CG  . ASP C 3 30  ? 102.674 90.923  171.590 1.00 110.24 ? 20  ASP B CG  1 
ATOM 4046 O OD1 . ASP C 3 30  ? 101.831 90.643  170.712 1.00 108.32 ? 20  ASP B OD1 1 
ATOM 4047 O OD2 . ASP C 3 30  ? 102.429 90.868  172.813 1.00 111.86 ? 20  ASP B OD2 1 
ATOM 4048 N N   . ALA C 3 31  ? 104.281 94.428  171.721 1.00 102.78 ? 21  ALA B N   1 
ATOM 4049 C CA  . ALA C 3 31  ? 103.828 95.653  172.374 1.00 102.18 ? 21  ALA B CA  1 
ATOM 4050 C C   . ALA C 3 31  ? 103.554 96.751  171.353 1.00 102.87 ? 21  ALA B C   1 
ATOM 4051 O O   . ALA C 3 31  ? 102.562 97.486  171.465 1.00 102.70 ? 21  ALA B O   1 
ATOM 4052 C CB  . ALA C 3 31  ? 104.864 96.116  173.398 1.00 101.21 ? 21  ALA B CB  1 
ATOM 4053 N N   . ARG C 3 32  ? 104.420 96.869  170.344 1.00 94.27  ? 22  ARG B N   1 
ATOM 4054 C CA  . ARG C 3 32  ? 104.251 97.892  169.321 1.00 91.28  ? 22  ARG B CA  1 
ATOM 4055 C C   . ARG C 3 32  ? 102.957 97.688  168.544 1.00 91.42  ? 22  ARG B C   1 
ATOM 4056 O O   . ARG C 3 32  ? 102.245 98.654  168.242 1.00 89.99  ? 22  ARG B O   1 
ATOM 4057 C CB  . ARG C 3 32  ? 105.462 97.874  168.387 1.00 89.23  ? 22  ARG B CB  1 
ATOM 4058 C CG  . ARG C 3 32  ? 105.606 99.091  167.506 1.00 87.48  ? 22  ARG B CG  1 
ATOM 4059 C CD  . ARG C 3 32  ? 106.892 99.037  166.700 1.00 87.69  ? 22  ARG B CD  1 
ATOM 4060 N NE  . ARG C 3 32  ? 108.074 99.146  167.548 1.00 86.67  ? 22  ARG B NE  1 
ATOM 4061 C CZ  . ARG C 3 32  ? 109.173 99.810  167.217 1.00 85.31  ? 22  ARG B CZ  1 
ATOM 4062 N NH1 . ARG C 3 32  ? 109.281 100.433 166.055 1.00 85.05  ? 22  ARG B NH1 1 
ATOM 4063 N NH2 . ARG C 3 32  ? 110.189 99.850  168.074 1.00 82.90  ? 22  ARG B NH2 1 
ATOM 4064 N N   . LYS C 3 33  ? 102.633 96.436  168.214 1.00 96.70  ? 23  LYS B N   1 
ATOM 4065 C CA  . LYS C 3 33  ? 101.376 96.152  167.531 1.00 97.29  ? 23  LYS B CA  1 
ATOM 4066 C C   . LYS C 3 33  ? 100.180 96.340  168.455 1.00 97.25  ? 23  LYS B C   1 
ATOM 4067 O O   . LYS C 3 33  ? 99.098  96.719  167.995 1.00 98.92  ? 23  LYS B O   1 
ATOM 4068 C CB  . LYS C 3 33  ? 101.392 94.732  166.966 1.00 97.22  ? 23  LYS B CB  1 
ATOM 4069 N N   . ALA C 3 34  ? 100.351 96.073  169.752 1.00 103.20 ? 24  ALA B N   1 
ATOM 4070 C CA  . ALA C 3 34  ? 99.260  96.277  170.699 1.00 105.83 ? 24  ALA B CA  1 
ATOM 4071 C C   . ALA C 3 34  ? 98.915  97.753  170.838 1.00 108.26 ? 24  ALA B C   1 
ATOM 4072 O O   . ALA C 3 34  ? 97.740  98.112  170.976 1.00 107.77 ? 24  ALA B O   1 
ATOM 4073 C CB  . ALA C 3 34  ? 99.625  95.680  172.057 1.00 105.20 ? 24  ALA B CB  1 
ATOM 4074 N N   . CYS C 3 35  ? 99.926  98.625  170.810 1.00 107.22 ? 25  CYS B N   1 
ATOM 4075 C CA  . CYS C 3 35  ? 99.668  100.056 170.935 1.00 105.31 ? 25  CYS B CA  1 
ATOM 4076 C C   . CYS C 3 35  ? 98.929  100.629 169.730 1.00 103.70 ? 25  CYS B C   1 
ATOM 4077 O O   . CYS C 3 35  ? 98.333  101.705 169.842 1.00 104.29 ? 25  CYS B O   1 
ATOM 4078 C CB  . CYS C 3 35  ? 100.980 100.814 171.144 1.00 106.24 ? 25  CYS B CB  1 
ATOM 4079 S SG  . CYS C 3 35  ? 101.864 100.370 172.655 1.00 109.55 ? 25  CYS B SG  1 
ATOM 4080 N N   . ALA C 3 36  ? 98.951  99.942  168.590 1.00 103.91 ? 26  ALA B N   1 
ATOM 4081 C CA  . ALA C 3 36  ? 98.321  100.455 167.381 1.00 103.55 ? 26  ALA B CA  1 
ATOM 4082 C C   . ALA C 3 36  ? 96.838  100.104 167.357 1.00 104.83 ? 26  ALA B C   1 
ATOM 4083 O O   . ALA C 3 36  ? 96.463  98.940  167.525 1.00 105.95 ? 26  ALA B O   1 
ATOM 4084 C CB  . ALA C 3 36  ? 99.013  99.894  166.141 1.00 103.32 ? 26  ALA B CB  1 
ATOM 4085 N N   . ASP C 3 37  ? 95.998  101.115 167.147 1.00 116.18 ? 27  ASP B N   1 
ATOM 4086 C CA  . ASP C 3 37  ? 94.556  100.927 167.039 1.00 118.60 ? 27  ASP B CA  1 
ATOM 4087 C C   . ASP C 3 37  ? 94.010  101.378 165.695 1.00 118.25 ? 27  ASP B C   1 
ATOM 4088 O O   . ASP C 3 37  ? 93.274  100.626 165.045 1.00 119.23 ? 27  ASP B O   1 
ATOM 4089 C CB  . ASP C 3 37  ? 93.842  101.679 168.172 1.00 118.97 ? 27  ASP B CB  1 
ATOM 4090 C CG  . ASP C 3 37  ? 94.581  101.582 169.487 1.00 121.15 ? 27  ASP B CG  1 
ATOM 4091 O OD1 . ASP C 3 37  ? 94.826  100.449 169.953 1.00 121.50 ? 27  ASP B OD1 1 
ATOM 4092 O OD2 . ASP C 3 37  ? 94.926  102.640 170.050 1.00 118.95 ? 27  ASP B OD2 1 
ATOM 4093 N N   . ALA C 3 38  ? 94.348  102.589 165.259 1.00 121.45 ? 28  ALA B N   1 
ATOM 4094 C CA  . ALA C 3 38  ? 93.896  103.113 163.980 1.00 121.01 ? 28  ALA B CA  1 
ATOM 4095 C C   . ALA C 3 38  ? 95.044  103.850 163.309 1.00 122.16 ? 28  ALA B C   1 
ATOM 4096 O O   . ALA C 3 38  ? 95.865  104.480 163.981 1.00 122.35 ? 28  ALA B O   1 
ATOM 4097 C CB  . ALA C 3 38  ? 92.694  104.050 164.149 1.00 118.95 ? 28  ALA B CB  1 
ATOM 4098 N N   . THR C 3 39  ? 95.100  103.762 161.984 1.00 110.78 ? 29  THR B N   1 
ATOM 4099 C CA  . THR C 3 39  ? 96.132  104.455 161.232 1.00 109.13 ? 29  THR B CA  1 
ATOM 4100 C C   . THR C 3 39  ? 95.863  105.958 161.216 1.00 107.04 ? 29  THR B C   1 
ATOM 4101 O O   . THR C 3 39  ? 94.747  106.420 161.468 1.00 106.21 ? 29  THR B O   1 
ATOM 4102 C CB  . THR C 3 39  ? 96.205  103.923 159.801 1.00 109.25 ? 29  THR B CB  1 
ATOM 4103 O OG1 . THR C 3 39  ? 94.884  103.842 159.252 1.00 110.43 ? 29  THR B OG1 1 
ATOM 4104 C CG2 . THR C 3 39  ? 96.841  102.540 159.780 1.00 106.25 ? 29  THR B CG2 1 
ATOM 4105 N N   . LEU C 3 40  ? 96.916  106.726 160.925 1.00 89.65  ? 30  LEU B N   1 
ATOM 4106 C CA  . LEU C 3 40  ? 96.755  108.171 160.804 1.00 89.22  ? 30  LEU B CA  1 
ATOM 4107 C C   . LEU C 3 40  ? 95.812  108.522 159.661 1.00 90.47  ? 30  LEU B C   1 
ATOM 4108 O O   . LEU C 3 40  ? 94.946  109.392 159.806 1.00 94.21  ? 30  LEU B O   1 
ATOM 4109 C CB  . LEU C 3 40  ? 98.116  108.840 160.602 1.00 93.08  ? 30  LEU B CB  1 
ATOM 4110 C CG  . LEU C 3 40  ? 98.107  110.333 160.263 1.00 90.04  ? 30  LEU B CG  1 
ATOM 4111 C CD1 . LEU C 3 40  ? 97.382  111.123 161.338 1.00 91.83  ? 30  LEU B CD1 1 
ATOM 4112 C CD2 . LEU C 3 40  ? 99.521  110.861 160.073 1.00 87.14  ? 30  LEU B CD2 1 
ATOM 4113 N N   . SER C 3 41  ? 95.951  107.837 158.522 1.00 98.65  ? 31  SER B N   1 
ATOM 4114 C CA  . SER C 3 41  ? 95.116  108.122 157.360 1.00 101.42 ? 31  SER B CA  1 
ATOM 4115 C C   . SER C 3 41  ? 93.639  107.853 157.619 1.00 100.84 ? 31  SER B C   1 
ATOM 4116 O O   . SER C 3 41  ? 92.789  108.368 156.884 1.00 97.62  ? 31  SER B O   1 
ATOM 4117 C CB  . SER C 3 41  ? 95.591  107.298 156.161 1.00 95.98  ? 31  SER B CB  1 
ATOM 4118 O OG  . SER C 3 41  ? 95.391  105.912 156.381 1.00 94.80  ? 31  SER B OG  1 
ATOM 4119 N N   . GLN C 3 42  ? 93.312  107.057 158.636 1.00 101.62 ? 32  GLN B N   1 
ATOM 4120 C CA  . GLN C 3 42  ? 91.921  106.770 158.965 1.00 100.47 ? 32  GLN B CA  1 
ATOM 4121 C C   . GLN C 3 42  ? 91.369  107.790 159.953 1.00 103.81 ? 32  GLN B C   1 
ATOM 4122 O O   . GLN C 3 42  ? 90.234  108.252 159.791 1.00 104.79 ? 32  GLN B O   1 
ATOM 4123 C CB  . GLN C 3 42  ? 91.822  105.315 159.472 1.00 100.77 ? 32  GLN B CB  1 
ATOM 4124 C CG  . GLN C 3 42  ? 90.441  104.650 159.775 1.00 102.83 ? 32  GLN B CG  1 
ATOM 4125 C CD  . GLN C 3 42  ? 89.575  105.255 160.886 1.00 103.71 ? 32  GLN B CD  1 
ATOM 4126 O OE1 . GLN C 3 42  ? 89.918  106.244 161.523 1.00 104.72 ? 32  GLN B OE1 1 
ATOM 4127 N NE2 . GLN C 3 42  ? 88.425  104.629 161.118 1.00 103.35 ? 32  GLN B NE2 1 
ATOM 4128 N N   . ILE C 3 43  ? 92.161  108.181 160.953 1.00 105.95 ? 33  ILE B N   1 
ATOM 4129 C CA  . ILE C 3 43  ? 91.665  109.090 161.982 1.00 105.20 ? 33  ILE B CA  1 
ATOM 4130 C C   . ILE C 3 43  ? 91.416  110.478 161.402 1.00 103.52 ? 33  ILE B C   1 
ATOM 4131 O O   . ILE C 3 43  ? 90.384  111.104 161.671 1.00 104.19 ? 33  ILE B O   1 
ATOM 4132 C CB  . ILE C 3 43  ? 92.646  109.137 163.166 1.00 103.39 ? 33  ILE B CB  1 
ATOM 4133 C CG1 . ILE C 3 43  ? 92.729  107.763 163.832 1.00 103.64 ? 33  ILE B CG1 1 
ATOM 4134 C CG2 . ILE C 3 43  ? 92.221  110.198 164.167 1.00 104.03 ? 33  ILE B CG2 1 
ATOM 4135 C CD1 . ILE C 3 43  ? 93.584  107.735 165.069 1.00 103.29 ? 33  ILE B CD1 1 
ATOM 4136 N N   . THR C 3 44  ? 92.347  110.973 160.588 1.00 99.57  ? 34  THR B N   1 
ATOM 4137 C CA  . THR C 3 44  ? 92.293  112.330 160.065 1.00 101.14 ? 34  THR B CA  1 
ATOM 4138 C C   . THR C 3 44  ? 91.598  112.416 158.705 1.00 101.70 ? 34  THR B C   1 
ATOM 4139 O O   . THR C 3 44  ? 91.793  113.394 157.975 1.00 103.89 ? 34  THR B O   1 
ATOM 4140 C CB  . THR C 3 44  ? 93.711  112.909 159.986 1.00 103.18 ? 34  THR B CB  1 
ATOM 4141 O OG1 . THR C 3 44  ? 93.649  114.333 159.846 1.00 104.37 ? 34  THR B OG1 1 
ATOM 4142 C CG2 . THR C 3 44  ? 94.487  112.310 158.821 1.00 102.63 ? 34  THR B CG2 1 
ATOM 4143 N N   . ASN C 3 45  ? 90.759  111.434 158.370 1.00 106.16 ? 35  ASN B N   1 
ATOM 4144 C CA  . ASN C 3 45  ? 90.121  111.378 157.059 1.00 110.32 ? 35  ASN B CA  1 
ATOM 4145 C C   . ASN C 3 45  ? 89.107  112.494 156.833 1.00 109.15 ? 35  ASN B C   1 
ATOM 4146 O O   . ASN C 3 45  ? 88.656  112.670 155.696 1.00 105.89 ? 35  ASN B O   1 
ATOM 4147 C CB  . ASN C 3 45  ? 89.438  110.021 156.874 1.00 109.89 ? 35  ASN B CB  1 
ATOM 4148 C CG  . ASN C 3 45  ? 89.475  109.540 155.437 1.00 109.67 ? 35  ASN B CG  1 
ATOM 4149 O OD1 . ASN C 3 45  ? 90.045  110.193 154.564 1.00 109.32 ? 35  ASN B OD1 1 
ATOM 4150 N ND2 . ASN C 3 45  ? 88.865  108.387 155.185 1.00 108.29 ? 35  ASN B ND2 1 
ATOM 4151 N N   . ASN C 3 46  ? 88.738  113.242 157.868 1.00 114.02 ? 36  ASN B N   1 
ATOM 4152 C CA  . ASN C 3 46  ? 87.682  114.241 157.767 1.00 114.95 ? 36  ASN B CA  1 
ATOM 4153 C C   . ASN C 3 46  ? 88.191  115.644 157.453 1.00 114.44 ? 36  ASN B C   1 
ATOM 4154 O O   . ASN C 3 46  ? 87.376  116.567 157.353 1.00 113.77 ? 36  ASN B O   1 
ATOM 4155 C CB  . ASN C 3 46  ? 86.867  114.275 159.064 1.00 114.90 ? 36  ASN B CB  1 
ATOM 4156 C CG  . ASN C 3 46  ? 85.990  113.051 159.232 1.00 114.25 ? 36  ASN B CG  1 
ATOM 4157 O OD1 . ASN C 3 46  ? 85.886  112.219 158.331 1.00 114.21 ? 36  ASN B OD1 1 
ATOM 4158 N ND2 . ASN C 3 46  ? 85.353  112.934 160.391 1.00 112.41 ? 36  ASN B ND2 1 
ATOM 4159 N N   . ILE C 3 47  ? 89.501  115.839 157.297 1.00 103.06 ? 37  ILE B N   1 
ATOM 4160 C CA  . ILE C 3 47  ? 90.017  117.174 157.015 1.00 103.99 ? 37  ILE B CA  1 
ATOM 4161 C C   . ILE C 3 47  ? 89.796  117.498 155.545 1.00 104.49 ? 37  ILE B C   1 
ATOM 4162 O O   . ILE C 3 47  ? 89.777  116.613 154.683 1.00 102.31 ? 37  ILE B O   1 
ATOM 4163 C CB  . ILE C 3 47  ? 91.510  117.303 157.377 1.00 100.72 ? 37  ILE B CB  1 
ATOM 4164 C CG1 . ILE C 3 47  ? 92.325  116.208 156.691 1.00 102.21 ? 37  ILE B CG1 1 
ATOM 4165 C CG2 . ILE C 3 47  ? 91.693  117.251 158.887 1.00 100.95 ? 37  ILE B CG2 1 
ATOM 4166 C CD1 . ILE C 3 47  ? 93.695  115.999 157.283 1.00 101.12 ? 37  ILE B CD1 1 
ATOM 4167 N N   . ASP C 3 48  ? 89.624  118.782 155.257 1.00 106.91 ? 38  ASP B N   1 
ATOM 4168 C CA  . ASP C 3 48  ? 89.560  119.221 153.874 1.00 106.89 ? 38  ASP B CA  1 
ATOM 4169 C C   . ASP C 3 48  ? 90.949  119.144 153.244 1.00 106.67 ? 38  ASP B C   1 
ATOM 4170 O O   . ASP C 3 48  ? 91.941  119.512 153.881 1.00 105.91 ? 38  ASP B O   1 
ATOM 4171 C CB  . ASP C 3 48  ? 89.022  120.648 153.790 1.00 106.96 ? 38  ASP B CB  1 
ATOM 4172 C CG  . ASP C 3 48  ? 87.794  120.858 154.654 1.00 106.98 ? 38  ASP B CG  1 
ATOM 4173 O OD1 . ASP C 3 48  ? 86.772  120.183 154.412 1.00 106.27 ? 38  ASP B OD1 1 
ATOM 4174 O OD2 . ASP C 3 48  ? 87.853  121.695 155.579 1.00 106.36 ? 38  ASP B OD2 1 
ATOM 4175 N N   . PRO C 3 49  ? 91.057  118.658 152.008 1.00 98.55  ? 39  PRO B N   1 
ATOM 4176 C CA  . PRO C 3 49  ? 92.367  118.614 151.351 1.00 96.44  ? 39  PRO B CA  1 
ATOM 4177 C C   . PRO C 3 49  ? 92.913  120.013 151.113 1.00 97.21  ? 39  PRO B C   1 
ATOM 4178 O O   . PRO C 3 49  ? 92.163  120.977 150.940 1.00 98.71  ? 39  PRO B O   1 
ATOM 4179 C CB  . PRO C 3 49  ? 92.079  117.891 150.029 1.00 96.73  ? 39  PRO B CB  1 
ATOM 4180 C CG  . PRO C 3 49  ? 90.791  117.162 150.262 1.00 97.75  ? 39  PRO B CG  1 
ATOM 4181 C CD  . PRO C 3 49  ? 90.006  118.045 151.182 1.00 96.87  ? 39  PRO B CD  1 
ATOM 4182 N N   . VAL C 3 50  ? 94.241  120.116 151.101 1.00 86.30  ? 40  VAL B N   1 
ATOM 4183 C CA  . VAL C 3 50  ? 94.915  121.401 150.950 1.00 85.34  ? 40  VAL B CA  1 
ATOM 4184 C C   . VAL C 3 50  ? 94.847  121.862 149.500 1.00 88.60  ? 40  VAL B C   1 
ATOM 4185 O O   . VAL C 3 50  ? 95.327  122.949 149.161 1.00 86.66  ? 40  VAL B O   1 
ATOM 4186 C CB  . VAL C 3 50  ? 96.375  121.320 151.430 1.00 82.09  ? 40  VAL B CB  1 
ATOM 4187 C CG1 . VAL C 3 50  ? 96.431  120.789 152.850 1.00 79.86  ? 40  VAL B CG1 1 
ATOM 4188 C CG2 . VAL C 3 50  ? 97.196  120.450 150.494 1.00 83.76  ? 40  VAL B CG2 1 
ATOM 4189 N N   . GLY C 3 51  ? 94.251  121.043 148.636 1.00 97.45  ? 41  GLY B N   1 
ATOM 4190 C CA  . GLY C 3 51  ? 94.134  121.421 147.242 1.00 96.35  ? 41  GLY B CA  1 
ATOM 4191 C C   . GLY C 3 51  ? 95.458  121.299 146.508 1.00 95.34  ? 41  GLY B C   1 
ATOM 4192 O O   . GLY C 3 51  ? 96.315  120.474 146.836 1.00 93.23  ? 41  GLY B O   1 
ATOM 4193 N N   . ARG C 3 52  ? 95.622  122.140 145.491 1.00 102.65 ? 42  ARG B N   1 
ATOM 4194 C CA  . ARG C 3 52  ? 96.828  122.159 144.675 1.00 100.25 ? 42  ARG B CA  1 
ATOM 4195 C C   . ARG C 3 52  ? 97.705  123.327 145.101 1.00 102.52 ? 42  ARG B C   1 
ATOM 4196 O O   . ARG C 3 52  ? 97.254  124.478 145.108 1.00 105.59 ? 42  ARG B O   1 
ATOM 4197 C CB  . ARG C 3 52  ? 96.481  122.274 143.191 1.00 100.99 ? 42  ARG B CB  1 
ATOM 4198 C CG  . ARG C 3 52  ? 97.466  121.582 142.265 1.00 101.88 ? 42  ARG B CG  1 
ATOM 4199 C CD  . ARG C 3 52  ? 97.269  120.074 142.286 1.00 102.18 ? 42  ARG B CD  1 
ATOM 4200 N NE  . ARG C 3 52  ? 98.361  119.365 141.630 1.00 106.07 ? 42  ARG B NE  1 
ATOM 4201 C CZ  . ARG C 3 52  ? 98.574  118.061 141.733 1.00 104.67 ? 42  ARG B CZ  1 
ATOM 4202 N NH1 . ARG C 3 52  ? 97.785  117.286 142.459 1.00 103.02 ? 42  ARG B NH1 1 
ATOM 4203 N NH2 . ARG C 3 52  ? 99.604  117.519 141.088 1.00 102.92 ? 42  ARG B NH2 1 
ATOM 4204 N N   . ILE C 3 53  ? 98.951  123.031 145.452 1.00 102.33 ? 43  ILE B N   1 
ATOM 4205 C CA  . ILE C 3 53  ? 99.901  124.032 145.922 1.00 104.05 ? 43  ILE B CA  1 
ATOM 4206 C C   . ILE C 3 53  ? 100.889 124.274 144.789 1.00 98.63  ? 43  ILE B C   1 
ATOM 4207 O O   . ILE C 3 53  ? 101.792 123.464 144.549 1.00 97.44  ? 43  ILE B O   1 
ATOM 4208 C CB  . ILE C 3 53  ? 100.610 123.592 147.207 1.00 100.87 ? 43  ILE B CB  1 
ATOM 4209 C CG1 . ILE C 3 53  ? 99.586  123.296 148.304 1.00 98.65  ? 43  ILE B CG1 1 
ATOM 4210 C CG2 . ILE C 3 53  ? 101.559 124.672 147.681 1.00 99.50  ? 43  ILE B CG2 1 
ATOM 4211 C CD1 . ILE C 3 53  ? 98.571  124.403 148.506 1.00 101.63 ? 43  ILE B CD1 1 
ATOM 4212 N N   . GLN C 3 54  ? 100.720 125.390 144.087 1.00 100.08 ? 44  GLN B N   1 
ATOM 4213 C CA  . GLN C 3 54  ? 101.567 125.751 142.957 1.00 102.34 ? 44  GLN B CA  1 
ATOM 4214 C C   . GLN C 3 54  ? 102.648 126.714 143.429 1.00 104.83 ? 44  GLN B C   1 
ATOM 4215 O O   . GLN C 3 54  ? 102.339 127.799 143.936 1.00 105.86 ? 44  GLN B O   1 
ATOM 4216 C CB  . GLN C 3 54  ? 100.734 126.382 141.841 1.00 104.59 ? 44  GLN B CB  1 
ATOM 4217 C CG  . GLN C 3 54  ? 101.544 126.871 140.650 1.00 103.94 ? 44  GLN B CG  1 
ATOM 4218 C CD  . GLN C 3 54  ? 101.940 125.747 139.713 1.00 105.58 ? 44  GLN B CD  1 
ATOM 4219 O OE1 . GLN C 3 54  ? 101.144 124.853 139.427 1.00 105.41 ? 44  GLN B OE1 1 
ATOM 4220 N NE2 . GLN C 3 54  ? 103.174 125.790 139.226 1.00 105.62 ? 44  GLN B NE2 1 
ATOM 4221 N N   . MET C 3 55  ? 103.908 126.321 143.263 1.00 87.01  ? 45  MET B N   1 
ATOM 4222 C CA  . MET C 3 55  ? 105.046 127.159 143.609 1.00 83.90  ? 45  MET B CA  1 
ATOM 4223 C C   . MET C 3 55  ? 105.780 127.580 142.344 1.00 83.76  ? 45  MET B C   1 
ATOM 4224 O O   . MET C 3 55  ? 106.005 126.764 141.445 1.00 81.82  ? 45  MET B O   1 
ATOM 4225 C CB  . MET C 3 55  ? 106.014 126.434 144.548 1.00 85.72  ? 45  MET B CB  1 
ATOM 4226 C CG  . MET C 3 55  ? 105.701 126.594 146.026 1.00 89.65  ? 45  MET B CG  1 
ATOM 4227 S SD  . MET C 3 55  ? 106.391 125.261 147.025 1.00 92.59  ? 45  MET B SD  1 
ATOM 4228 C CE  . MET C 3 55  ? 105.028 124.104 147.054 1.00 84.56  ? 45  MET B CE  1 
ATOM 4229 N N   . ARG C 3 56  ? 106.152 128.854 142.281 1.00 78.51  ? 46  ARG B N   1 
ATOM 4230 C CA  . ARG C 3 56  ? 106.836 129.423 141.131 1.00 77.90  ? 46  ARG B CA  1 
ATOM 4231 C C   . ARG C 3 56  ? 108.251 129.829 141.520 1.00 78.28  ? 46  ARG B C   1 
ATOM 4232 O O   . ARG C 3 56  ? 108.477 130.357 142.613 1.00 80.84  ? 46  ARG B O   1 
ATOM 4233 C CB  . ARG C 3 56  ? 106.072 130.634 140.586 1.00 79.19  ? 46  ARG B CB  1 
ATOM 4234 C CG  . ARG C 3 56  ? 106.778 131.363 139.457 1.00 80.52  ? 46  ARG B CG  1 
ATOM 4235 C CD  . ARG C 3 56  ? 106.154 132.725 139.197 1.00 81.82  ? 46  ARG B CD  1 
ATOM 4236 N NE  . ARG C 3 56  ? 107.158 133.781 139.138 1.00 82.13  ? 46  ARG B NE  1 
ATOM 4237 C CZ  . ARG C 3 56  ? 108.010 133.957 138.137 1.00 81.64  ? 46  ARG B CZ  1 
ATOM 4238 N NH1 . ARG C 3 56  ? 107.998 133.173 137.072 1.00 79.50  ? 46  ARG B NH1 1 
ATOM 4239 N NH2 . ARG C 3 56  ? 108.896 134.947 138.207 1.00 82.83  ? 46  ARG B NH2 1 
ATOM 4240 N N   . THR C 3 57  ? 109.201 129.578 140.621 1.00 69.57  ? 47  THR B N   1 
ATOM 4241 C CA  . THR C 3 57  ? 110.600 129.912 140.864 1.00 70.10  ? 47  THR B CA  1 
ATOM 4242 C C   . THR C 3 57  ? 110.757 131.425 140.946 1.00 72.24  ? 47  THR B C   1 
ATOM 4243 O O   . THR C 3 57  ? 110.569 132.132 139.951 1.00 73.15  ? 47  THR B O   1 
ATOM 4244 C CB  . THR C 3 57  ? 111.479 129.337 139.758 1.00 67.65  ? 47  THR B CB  1 
ATOM 4245 O OG1 . THR C 3 57  ? 111.489 127.908 139.847 1.00 64.95  ? 47  THR B OG1 1 
ATOM 4246 C CG2 . THR C 3 57  ? 112.901 129.855 139.884 1.00 64.10  ? 47  THR B CG2 1 
ATOM 4247 N N   . ARG C 3 58  ? 111.102 131.926 142.132 1.00 66.71  ? 48  ARG B N   1 
ATOM 4248 C CA  . ARG C 3 58  ? 111.302 133.356 142.327 1.00 66.00  ? 48  ARG B CA  1 
ATOM 4249 C C   . ARG C 3 58  ? 112.735 133.785 142.040 1.00 68.33  ? 48  ARG B C   1 
ATOM 4250 O O   . ARG C 3 58  ? 112.956 134.856 141.465 1.00 75.57  ? 48  ARG B O   1 
ATOM 4251 C CB  . ARG C 3 58  ? 110.919 133.751 143.754 1.00 66.59  ? 48  ARG B CB  1 
ATOM 4252 C CG  . ARG C 3 58  ? 109.585 133.193 144.211 1.00 68.22  ? 48  ARG B CG  1 
ATOM 4253 C CD  . ARG C 3 58  ? 108.431 133.982 143.619 1.00 69.53  ? 48  ARG B CD  1 
ATOM 4254 N NE  . ARG C 3 58  ? 107.137 133.464 144.045 1.00 70.16  ? 48  ARG B NE  1 
ATOM 4255 C CZ  . ARG C 3 58  ? 105.974 134.038 143.771 1.00 72.56  ? 48  ARG B CZ  1 
ATOM 4256 N NH1 . ARG C 3 58  ? 105.905 135.158 143.070 1.00 73.14  ? 48  ARG B NH1 1 
ATOM 4257 N NH2 . ARG C 3 58  ? 104.853 133.476 144.213 1.00 70.30  ? 48  ARG B NH2 1 
ATOM 4258 N N   . ARG C 3 59  ? 113.714 132.972 142.430 1.00 62.40  ? 49  ARG B N   1 
ATOM 4259 C CA  . ARG C 3 59  ? 115.119 133.266 142.198 1.00 63.03  ? 49  ARG B CA  1 
ATOM 4260 C C   . ARG C 3 59  ? 115.809 132.035 141.629 1.00 59.41  ? 49  ARG B C   1 
ATOM 4261 O O   . ARG C 3 59  ? 115.358 130.902 141.811 1.00 65.32  ? 49  ARG B O   1 
ATOM 4262 C CB  . ARG C 3 59  ? 115.837 133.704 143.486 1.00 65.93  ? 49  ARG B CB  1 
ATOM 4263 C CG  . ARG C 3 59  ? 115.031 134.619 144.393 1.00 63.03  ? 49  ARG B CG  1 
ATOM 4264 C CD  . ARG C 3 59  ? 115.032 136.049 143.885 1.00 63.97  ? 49  ARG B CD  1 
ATOM 4265 N NE  . ARG C 3 59  ? 114.212 136.917 144.722 1.00 68.06  ? 49  ARG B NE  1 
ATOM 4266 C CZ  . ARG C 3 59  ? 114.076 138.223 144.540 1.00 68.45  ? 49  ARG B CZ  1 
ATOM 4267 N NH1 . ARG C 3 59  ? 114.701 138.853 143.559 1.00 67.00  ? 49  ARG B NH1 1 
ATOM 4268 N NH2 . ARG C 3 59  ? 113.295 138.915 145.364 1.00 64.03  ? 49  ARG B NH2 1 
ATOM 4269 N N   . THR C 3 60  ? 116.914 132.275 140.929 1.00 54.22  ? 50  THR B N   1 
ATOM 4270 C CA  . THR C 3 60  ? 117.764 131.205 140.415 1.00 56.94  ? 50  THR B CA  1 
ATOM 4271 C C   . THR C 3 60  ? 119.208 131.597 140.690 1.00 58.09  ? 50  THR B C   1 
ATOM 4272 O O   . THR C 3 60  ? 119.739 132.511 140.051 1.00 56.42  ? 50  THR B O   1 
ATOM 4273 C CB  . THR C 3 60  ? 117.533 130.970 138.923 1.00 62.88  ? 50  THR B CB  1 
ATOM 4274 O OG1 . THR C 3 60  ? 116.137 130.754 138.685 1.00 67.18  ? 50  THR B OG1 1 
ATOM 4275 C CG2 . THR C 3 60  ? 118.315 129.753 138.451 1.00 60.16  ? 50  THR B CG2 1 
ATOM 4276 N N   . LEU C 3 61  ? 119.838 130.910 141.637 1.00 59.71  ? 51  LEU B N   1 
ATOM 4277 C CA  . LEU C 3 61  ? 121.181 131.253 142.092 1.00 58.79  ? 51  LEU B CA  1 
ATOM 4278 C C   . LEU C 3 61  ? 122.196 130.524 141.222 1.00 60.81  ? 51  LEU B C   1 
ATOM 4279 O O   . LEU C 3 61  ? 122.285 129.293 141.257 1.00 62.95  ? 51  LEU B O   1 
ATOM 4280 C CB  . LEU C 3 61  ? 121.350 130.888 143.564 1.00 51.45  ? 51  LEU B CB  1 
ATOM 4281 C CG  . LEU C 3 61  ? 120.301 131.489 144.501 1.00 53.98  ? 51  LEU B CG  1 
ATOM 4282 C CD1 . LEU C 3 61  ? 120.370 130.837 145.867 1.00 55.76  ? 51  LEU B CD1 1 
ATOM 4283 C CD2 . LEU C 3 61  ? 120.483 132.990 144.617 1.00 57.64  ? 51  LEU B CD2 1 
ATOM 4284 N N   . ARG C 3 62  ? 122.963 131.282 140.444 1.00 57.52  ? 52  ARG B N   1 
ATOM 4285 C CA  . ARG C 3 62  ? 123.974 130.726 139.562 1.00 60.52  ? 52  ARG B CA  1 
ATOM 4286 C C   . ARG C 3 62  ? 125.358 131.189 139.998 1.00 61.91  ? 52  ARG B C   1 
ATOM 4287 O O   . ARG C 3 62  ? 125.513 132.207 140.678 1.00 60.85  ? 52  ARG B O   1 
ATOM 4288 C CB  . ARG C 3 62  ? 123.723 131.125 138.102 1.00 61.01  ? 52  ARG B CB  1 
ATOM 4289 C CG  . ARG C 3 62  ? 122.300 130.888 137.624 1.00 55.37  ? 52  ARG B CG  1 
ATOM 4290 C CD  . ARG C 3 62  ? 122.147 131.256 136.155 1.00 58.43  ? 52  ARG B CD  1 
ATOM 4291 N NE  . ARG C 3 62  ? 121.728 132.639 135.968 1.00 62.72  ? 52  ARG B NE  1 
ATOM 4292 C CZ  . ARG C 3 62  ? 120.492 133.082 136.158 1.00 62.59  ? 52  ARG B CZ  1 
ATOM 4293 N NH1 . ARG C 3 62  ? 119.515 132.269 136.525 1.00 63.12  ? 52  ARG B NH1 1 
ATOM 4294 N NH2 . ARG C 3 62  ? 120.229 134.372 135.971 1.00 57.29  ? 52  ARG B NH2 1 
ATOM 4295 N N   . GLY C 3 63  ? 126.368 130.429 139.585 1.00 57.51  ? 53  GLY B N   1 
ATOM 4296 C CA  . GLY C 3 63  ? 127.739 130.716 139.952 1.00 56.43  ? 53  GLY B CA  1 
ATOM 4297 C C   . GLY C 3 63  ? 128.540 129.461 140.225 1.00 59.81  ? 53  GLY B C   1 
ATOM 4298 O O   . GLY C 3 63  ? 129.765 129.449 140.073 1.00 60.60  ? 53  GLY B O   1 
ATOM 4299 N N   . HIS C 3 64  ? 127.856 128.394 140.628 1.00 61.13  ? 54  HIS B N   1 
ATOM 4300 C CA  . HIS C 3 64  ? 128.514 127.111 140.813 1.00 57.56  ? 54  HIS B CA  1 
ATOM 4301 C C   . HIS C 3 64  ? 128.833 126.481 139.463 1.00 64.04  ? 54  HIS B C   1 
ATOM 4302 O O   . HIS C 3 64  ? 128.095 126.641 138.487 1.00 64.98  ? 54  HIS B O   1 
ATOM 4303 C CB  . HIS C 3 64  ? 127.635 126.174 141.639 1.00 55.66  ? 54  HIS B CB  1 
ATOM 4304 C CG  . HIS C 3 64  ? 127.813 126.326 143.117 1.00 53.62  ? 54  HIS B CG  1 
ATOM 4305 N ND1 . HIS C 3 64  ? 129.053 126.349 143.719 1.00 53.50  ? 54  HIS B ND1 1 
ATOM 4306 C CD2 . HIS C 3 64  ? 126.909 126.466 144.115 1.00 57.87  ? 54  HIS B CD2 1 
ATOM 4307 C CE1 . HIS C 3 64  ? 128.904 126.494 145.023 1.00 54.81  ? 54  HIS B CE1 1 
ATOM 4308 N NE2 . HIS C 3 64  ? 127.613 126.569 145.289 1.00 54.35  ? 54  HIS B NE2 1 
ATOM 4309 N N   . LEU C 3 65  ? 129.954 125.761 139.411 1.00 68.38  ? 55  LEU B N   1 
ATOM 4310 C CA  . LEU C 3 65  ? 130.432 125.156 138.174 1.00 67.95  ? 55  LEU B CA  1 
ATOM 4311 C C   . LEU C 3 65  ? 130.488 123.634 138.253 1.00 72.30  ? 55  LEU B C   1 
ATOM 4312 O O   . LEU C 3 65  ? 131.174 123.004 137.443 1.00 75.23  ? 55  LEU B O   1 
ATOM 4313 C CB  . LEU C 3 65  ? 131.807 125.716 137.807 1.00 64.40  ? 55  LEU B CB  1 
ATOM 4314 C CG  . LEU C 3 65  ? 131.868 127.218 137.523 1.00 67.84  ? 55  LEU B CG  1 
ATOM 4315 C CD1 . LEU C 3 65  ? 133.254 127.760 137.820 1.00 71.13  ? 55  LEU B CD1 1 
ATOM 4316 C CD2 . LEU C 3 65  ? 131.473 127.510 136.084 1.00 67.96  ? 55  LEU B CD2 1 
ATOM 4317 N N   . ALA C 3 66  ? 129.779 123.029 139.201 1.00 66.31  ? 56  ALA B N   1 
ATOM 4318 C CA  . ALA C 3 66  ? 129.824 121.583 139.382 1.00 62.40  ? 56  ALA B CA  1 
ATOM 4319 C C   . ALA C 3 66  ? 128.627 121.154 140.222 1.00 60.31  ? 56  ALA B C   1 
ATOM 4320 O O   . ALA C 3 66  ? 127.823 121.979 140.663 1.00 61.36  ? 56  ALA B O   1 
ATOM 4321 C CB  . ALA C 3 66  ? 131.146 121.153 140.021 1.00 58.82  ? 56  ALA B CB  1 
ATOM 4322 N N   . LYS C 3 67  ? 128.522 119.844 140.447 1.00 61.29  ? 57  LYS B N   1 
ATOM 4323 C CA  . LYS C 3 67  ? 127.391 119.293 141.182 1.00 64.36  ? 57  LYS B CA  1 
ATOM 4324 C C   . LYS C 3 67  ? 127.358 119.818 142.611 1.00 68.13  ? 57  LYS B C   1 
ATOM 4325 O O   . LYS C 3 67  ? 128.393 119.945 143.267 1.00 74.40  ? 57  LYS B O   1 
ATOM 4326 C CB  . LYS C 3 67  ? 127.464 117.767 141.209 1.00 63.36  ? 57  LYS B CB  1 
ATOM 4327 C CG  . LYS C 3 67  ? 127.382 117.088 139.861 1.00 63.65  ? 57  LYS B CG  1 
ATOM 4328 C CD  . LYS C 3 67  ? 127.427 115.583 140.047 1.00 67.70  ? 57  LYS B CD  1 
ATOM 4329 C CE  . LYS C 3 67  ? 127.451 114.848 138.724 1.00 64.83  ? 57  LYS B CE  1 
ATOM 4330 N NZ  . LYS C 3 67  ? 127.475 113.377 138.940 1.00 61.69  ? 57  LYS B NZ  1 
ATOM 4331 N N   . ILE C 3 68  ? 126.153 120.097 143.099 1.00 56.64  ? 58  ILE B N   1 
ATOM 4332 C CA  . ILE C 3 68  ? 125.935 120.569 144.462 1.00 53.37  ? 58  ILE B CA  1 
ATOM 4333 C C   . ILE C 3 68  ? 125.383 119.417 145.288 1.00 54.48  ? 58  ILE B C   1 
ATOM 4334 O O   . ILE C 3 68  ? 124.384 118.795 144.906 1.00 58.18  ? 58  ILE B O   1 
ATOM 4335 C CB  . ILE C 3 68  ? 124.975 121.770 144.485 1.00 53.97  ? 58  ILE B CB  1 
ATOM 4336 C CG1 . ILE C 3 68  ? 125.634 122.991 143.849 1.00 53.21  ? 58  ILE B CG1 1 
ATOM 4337 C CG2 . ILE C 3 68  ? 124.537 122.079 145.905 1.00 53.24  ? 58  ILE B CG2 1 
ATOM 4338 C CD1 . ILE C 3 68  ? 124.654 123.926 143.195 1.00 58.59  ? 58  ILE B CD1 1 
ATOM 4339 N N   . TYR C 3 69  ? 126.030 119.127 146.417 1.00 54.27  ? 59  TYR B N   1 
ATOM 4340 C CA  . TYR C 3 69  ? 125.582 118.054 147.296 1.00 54.44  ? 59  TYR B CA  1 
ATOM 4341 C C   . TYR C 3 69  ? 124.830 118.534 148.526 1.00 56.78  ? 59  TYR B C   1 
ATOM 4342 O O   . TYR C 3 69  ? 124.052 117.759 149.092 1.00 56.50  ? 59  TYR B O   1 
ATOM 4343 C CB  . TYR C 3 69  ? 126.767 117.203 147.762 1.00 53.90  ? 59  TYR B CB  1 
ATOM 4344 C CG  . TYR C 3 69  ? 127.483 116.480 146.655 1.00 56.30  ? 59  TYR B CG  1 
ATOM 4345 C CD1 . TYR C 3 69  ? 126.966 115.306 146.125 1.00 61.86  ? 59  TYR B CD1 1 
ATOM 4346 C CD2 . TYR C 3 69  ? 128.672 116.963 146.141 1.00 55.03  ? 59  TYR B CD2 1 
ATOM 4347 C CE1 . TYR C 3 69  ? 127.616 114.636 145.114 1.00 62.69  ? 59  TYR B CE1 1 
ATOM 4348 C CE2 . TYR C 3 69  ? 129.325 116.302 145.134 1.00 55.06  ? 59  TYR B CE2 1 
ATOM 4349 C CZ  . TYR C 3 69  ? 128.796 115.139 144.621 1.00 60.76  ? 59  TYR B CZ  1 
ATOM 4350 O OH  . TYR C 3 69  ? 129.451 114.477 143.611 1.00 63.57  ? 59  TYR B OH  1 
ATOM 4351 N N   . ALA C 3 70  ? 125.033 119.775 148.960 1.00 44.68  ? 60  ALA B N   1 
ATOM 4352 C CA  . ALA C 3 70  ? 124.443 120.204 150.216 1.00 43.16  ? 60  ALA B CA  1 
ATOM 4353 C C   . ALA C 3 70  ? 124.186 121.701 150.194 1.00 40.98  ? 60  ALA B C   1 
ATOM 4354 O O   . ALA C 3 70  ? 124.713 122.436 149.356 1.00 42.65  ? 60  ALA B O   1 
ATOM 4355 C CB  . ALA C 3 70  ? 125.334 119.836 151.402 1.00 48.73  ? 60  ALA B CB  1 
ATOM 4356 N N   . MET C 3 71  ? 123.368 122.137 151.145 1.00 55.60  ? 61  MET B N   1 
ATOM 4357 C CA  . MET C 3 71  ? 122.907 123.511 151.261 1.00 55.76  ? 61  MET B CA  1 
ATOM 4358 C C   . MET C 3 71  ? 122.251 123.675 152.621 1.00 53.84  ? 61  MET B C   1 
ATOM 4359 O O   . MET C 3 71  ? 121.639 122.737 153.141 1.00 60.75  ? 61  MET B O   1 
ATOM 4360 C CB  . MET C 3 71  ? 121.948 123.862 150.110 1.00 51.45  ? 61  MET B CB  1 
ATOM 4361 C CG  . MET C 3 71  ? 120.492 123.407 150.261 1.00 52.54  ? 61  MET B CG  1 
ATOM 4362 S SD  . MET C 3 71  ? 119.424 124.324 151.381 1.00 73.04  ? 61  MET B SD  1 
ATOM 4363 C CE  . MET C 3 71  ? 119.083 125.734 150.346 1.00 58.88  ? 61  MET B CE  1 
ATOM 4364 N N   . HIS C 3 72  ? 122.407 124.859 153.204 1.00 50.15  ? 62  HIS B N   1 
ATOM 4365 C CA  . HIS C 3 72  ? 121.794 125.153 154.489 1.00 55.71  ? 62  HIS B CA  1 
ATOM 4366 C C   . HIS C 3 72  ? 121.355 126.607 154.522 1.00 64.64  ? 62  HIS B C   1 
ATOM 4367 O O   . HIS C 3 72  ? 121.972 127.475 153.900 1.00 74.10  ? 62  HIS B O   1 
ATOM 4368 C CB  . HIS C 3 72  ? 122.744 124.859 155.651 1.00 62.51  ? 62  HIS B CB  1 
ATOM 4369 C CG  . HIS C 3 72  ? 122.045 124.462 156.912 1.00 62.03  ? 62  HIS B CG  1 
ATOM 4370 N ND1 . HIS C 3 72  ? 121.971 125.284 158.015 1.00 64.48  ? 62  HIS B ND1 1 
ATOM 4371 C CD2 . HIS C 3 72  ? 121.380 123.331 157.242 1.00 63.47  ? 62  HIS B CD2 1 
ATOM 4372 C CE1 . HIS C 3 72  ? 121.295 124.674 158.972 1.00 61.59  ? 62  HIS B CE1 1 
ATOM 4373 N NE2 . HIS C 3 72  ? 120.925 123.487 158.528 1.00 57.79  ? 62  HIS B NE2 1 
ATOM 4374 N N   . TRP C 3 73  ? 120.281 126.861 155.261 1.00 45.64  ? 63  TRP B N   1 
ATOM 4375 C CA  . TRP C 3 73  ? 119.684 128.183 155.373 1.00 37.25  ? 63  TRP B CA  1 
ATOM 4376 C C   . TRP C 3 73  ? 120.166 128.869 156.642 1.00 39.93  ? 63  TRP B C   1 
ATOM 4377 O O   . TRP C 3 73  ? 120.334 128.226 157.682 1.00 46.93  ? 63  TRP B O   1 
ATOM 4378 C CB  . TRP C 3 73  ? 118.157 128.084 155.393 1.00 37.95  ? 63  TRP B CB  1 
ATOM 4379 C CG  . TRP C 3 73  ? 117.518 128.112 154.042 1.00 44.75  ? 63  TRP B CG  1 
ATOM 4380 C CD1 . TRP C 3 73  ? 117.043 127.045 153.340 1.00 40.62  ? 63  TRP B CD1 1 
ATOM 4381 C CD2 . TRP C 3 73  ? 117.254 129.269 153.241 1.00 44.87  ? 63  TRP B CD2 1 
ATOM 4382 N NE1 . TRP C 3 73  ? 116.515 127.463 152.144 1.00 44.70  ? 63  TRP B NE1 1 
ATOM 4383 C CE2 . TRP C 3 73  ? 116.631 128.825 152.060 1.00 42.44  ? 63  TRP B CE2 1 
ATOM 4384 C CE3 . TRP C 3 73  ? 117.492 130.635 153.404 1.00 47.46  ? 63  TRP B CE3 1 
ATOM 4385 C CZ2 . TRP C 3 73  ? 116.242 129.697 151.050 1.00 36.23  ? 63  TRP B CZ2 1 
ATOM 4386 C CZ3 . TRP C 3 73  ? 117.106 131.498 152.400 1.00 43.53  ? 63  TRP B CZ3 1 
ATOM 4387 C CH2 . TRP C 3 73  ? 116.488 131.027 151.238 1.00 31.54  ? 63  TRP B CH2 1 
ATOM 4388 N N   . GLY C 3 74  ? 120.388 130.175 156.553 1.00 45.55  ? 64  GLY B N   1 
ATOM 4389 C CA  . GLY C 3 74  ? 120.688 130.944 157.739 1.00 44.23  ? 64  GLY B CA  1 
ATOM 4390 C C   . GLY C 3 74  ? 119.491 131.050 158.662 1.00 49.79  ? 64  GLY B C   1 
ATOM 4391 O O   . GLY C 3 74  ? 118.339 130.886 158.259 1.00 54.10  ? 64  GLY B O   1 
ATOM 4392 N N   . THR C 3 75  ? 119.775 131.322 159.937 1.00 51.73  ? 65  THR B N   1 
ATOM 4393 C CA  . THR C 3 75  ? 118.698 131.489 160.907 1.00 51.43  ? 65  THR B CA  1 
ATOM 4394 C C   . THR C 3 75  ? 117.836 132.699 160.568 1.00 50.96  ? 65  THR B C   1 
ATOM 4395 O O   . THR C 3 75  ? 116.633 132.709 160.853 1.00 55.89  ? 65  THR B O   1 
ATOM 4396 C CB  . THR C 3 75  ? 119.282 131.611 162.316 1.00 54.38  ? 65  THR B CB  1 
ATOM 4397 O OG1 . THR C 3 75  ? 119.907 130.374 162.679 1.00 53.77  ? 65  THR B OG1 1 
ATOM 4398 C CG2 . THR C 3 75  ? 118.197 131.921 163.335 1.00 51.42  ? 65  THR B CG2 1 
ATOM 4399 N N   . ASP C 3 76  ? 118.421 133.706 159.922 1.00 37.90  ? 66  ASP B N   1 
ATOM 4400 C CA  . ASP C 3 76  ? 117.690 134.896 159.512 1.00 40.72  ? 66  ASP B CA  1 
ATOM 4401 C C   . ASP C 3 76  ? 116.919 134.700 158.214 1.00 45.61  ? 66  ASP B C   1 
ATOM 4402 O O   . ASP C 3 76  ? 116.276 135.647 157.749 1.00 51.86  ? 66  ASP B O   1 
ATOM 4403 C CB  . ASP C 3 76  ? 118.654 136.078 159.372 1.00 46.63  ? 66  ASP B CB  1 
ATOM 4404 C CG  . ASP C 3 76  ? 119.827 135.770 158.463 1.00 51.49  ? 66  ASP B CG  1 
ATOM 4405 O OD1 . ASP C 3 76  ? 119.615 135.621 157.242 1.00 51.92  ? 66  ASP B OD1 1 
ATOM 4406 O OD2 . ASP C 3 76  ? 120.964 135.675 158.970 1.00 52.34  ? 66  ASP B OD2 1 
ATOM 4407 N N   . SER C 3 77  ? 116.963 133.501 157.629 1.00 36.06  ? 67  SER B N   1 
ATOM 4408 C CA  . SER C 3 77  ? 116.222 133.157 156.412 1.00 34.79  ? 67  SER B CA  1 
ATOM 4409 C C   . SER C 3 77  ? 116.542 134.098 155.255 1.00 38.35  ? 67  SER B C   1 
ATOM 4410 O O   . SER C 3 77  ? 115.687 134.373 154.411 1.00 43.74  ? 67  SER B O   1 
ATOM 4411 C CB  . SER C 3 77  ? 114.708 133.112 156.658 1.00 45.09  ? 67  SER B CB  1 
ATOM 4412 O OG  . SER C 3 77  ? 114.264 134.116 157.553 1.00 44.70  ? 67  SER B OG  1 
ATOM 4413 N N   . ARG C 3 78  ? 117.776 134.597 155.199 1.00 48.56  ? 68  ARG B N   1 
ATOM 4414 C CA  . ARG C 3 78  ? 118.181 135.476 154.110 1.00 43.66  ? 68  ARG B CA  1 
ATOM 4415 C C   . ARG C 3 78  ? 119.506 135.027 153.505 1.00 45.53  ? 68  ARG B C   1 
ATOM 4416 O O   . ARG C 3 78  ? 119.749 135.226 152.311 1.00 50.99  ? 68  ARG B O   1 
ATOM 4417 C CB  . ARG C 3 78  ? 118.277 136.924 154.598 1.00 41.24  ? 68  ARG B CB  1 
ATOM 4418 C CG  . ARG C 3 78  ? 118.811 137.888 153.558 1.00 45.58  ? 68  ARG B CG  1 
ATOM 4419 C CD  . ARG C 3 78  ? 118.355 139.310 153.815 1.00 46.86  ? 68  ARG B CD  1 
ATOM 4420 N NE  . ARG C 3 78  ? 118.842 140.217 152.783 1.00 51.42  ? 68  ARG B NE  1 
ATOM 4421 C CZ  . ARG C 3 78  ? 118.486 141.489 152.673 1.00 49.71  ? 68  ARG B CZ  1 
ATOM 4422 N NH1 . ARG C 3 78  ? 117.637 142.044 153.522 1.00 47.62  ? 68  ARG B NH1 1 
ATOM 4423 N NH2 . ARG C 3 78  ? 118.995 142.222 151.688 1.00 45.96  ? 68  ARG B NH2 1 
ATOM 4424 N N   . LEU C 3 79  ? 120.364 134.409 154.311 1.00 35.71  ? 69  LEU B N   1 
ATOM 4425 C CA  . LEU C 3 79  ? 121.691 133.999 153.875 1.00 35.86  ? 69  LEU B CA  1 
ATOM 4426 C C   . LEU C 3 79  ? 121.743 132.492 153.675 1.00 41.21  ? 69  LEU B C   1 
ATOM 4427 O O   . LEU C 3 79  ? 121.187 131.730 154.470 1.00 37.97  ? 69  LEU B O   1 
ATOM 4428 C CB  . LEU C 3 79  ? 122.759 134.426 154.883 1.00 38.28  ? 69  LEU B CB  1 
ATOM 4429 C CG  . LEU C 3 79  ? 123.050 135.923 154.954 1.00 36.69  ? 69  LEU B CG  1 
ATOM 4430 C CD1 . LEU C 3 79  ? 123.562 136.303 156.331 1.00 43.71  ? 69  LEU B CD1 1 
ATOM 4431 C CD2 . LEU C 3 79  ? 124.047 136.309 153.880 1.00 38.66  ? 69  LEU B CD2 1 
ATOM 4432 N N   . LEU C 3 80  ? 122.416 132.072 152.611 1.00 53.02  ? 70  LEU B N   1 
ATOM 4433 C CA  . LEU C 3 80  ? 122.537 130.669 152.252 1.00 42.37  ? 70  LEU B CA  1 
ATOM 4434 C C   . LEU C 3 80  ? 123.993 130.225 152.324 1.00 49.61  ? 70  LEU B C   1 
ATOM 4435 O O   . LEU C 3 80  ? 124.905 131.018 152.570 1.00 59.41  ? 70  LEU B O   1 
ATOM 4436 C CB  . LEU C 3 80  ? 121.976 130.421 150.853 1.00 39.93  ? 70  LEU B CB  1 
ATOM 4437 C CG  . LEU C 3 80  ? 120.484 130.120 150.809 1.00 45.79  ? 70  LEU B CG  1 
ATOM 4438 C CD1 . LEU C 3 80  ? 119.982 130.095 149.381 1.00 46.90  ? 70  LEU B CD1 1 
ATOM 4439 C CD2 . LEU C 3 80  ? 120.201 128.818 151.510 1.00 50.26  ? 70  LEU B CD2 1 
ATOM 4440 N N   . VAL C 3 81  ? 124.199 128.932 152.098 1.00 47.82  ? 71  VAL B N   1 
ATOM 4441 C CA  . VAL C 3 81  ? 125.531 128.349 151.991 1.00 33.04  ? 71  VAL B CA  1 
ATOM 4442 C C   . VAL C 3 81  ? 125.418 127.086 151.146 1.00 40.87  ? 71  VAL B C   1 
ATOM 4443 O O   . VAL C 3 81  ? 124.435 126.348 151.244 1.00 55.53  ? 71  VAL B O   1 
ATOM 4444 C CB  . VAL C 3 81  ? 126.132 128.065 153.384 1.00 26.32  ? 71  VAL B CB  1 
ATOM 4445 C CG1 . VAL C 3 81  ? 125.351 126.981 154.106 1.00 38.76  ? 71  VAL B CG1 1 
ATOM 4446 C CG2 . VAL C 3 81  ? 127.588 127.696 153.268 1.00 40.07  ? 71  VAL B CG2 1 
ATOM 4447 N N   . SER C 3 82  ? 126.414 126.847 150.294 1.00 36.78  ? 72  SER B N   1 
ATOM 4448 C CA  . SER C 3 82  ? 126.365 125.698 149.398 1.00 38.09  ? 72  SER B CA  1 
ATOM 4449 C C   . SER C 3 82  ? 127.773 125.262 149.028 1.00 40.37  ? 72  SER B C   1 
ATOM 4450 O O   . SER C 3 82  ? 128.625 126.104 148.733 1.00 54.99  ? 72  SER B O   1 
ATOM 4451 C CB  . SER C 3 82  ? 125.568 126.023 148.132 1.00 44.16  ? 72  SER B CB  1 
ATOM 4452 O OG  . SER C 3 82  ? 126.361 126.743 147.206 1.00 43.99  ? 72  SER B OG  1 
ATOM 4453 N N   . ALA C 3 83  ? 128.009 123.951 149.040 1.00 28.78  ? 73  ALA B N   1 
ATOM 4454 C CA  . ALA C 3 83  ? 129.273 123.365 148.619 1.00 35.56  ? 73  ALA B CA  1 
ATOM 4455 C C   . ALA C 3 83  ? 129.061 122.520 147.371 1.00 41.87  ? 73  ALA B C   1 
ATOM 4456 O O   . ALA C 3 83  ? 128.020 121.874 147.216 1.00 51.45  ? 73  ALA B O   1 
ATOM 4457 C CB  . ALA C 3 83  ? 129.891 122.509 149.725 1.00 37.97  ? 73  ALA B CB  1 
ATOM 4458 N N   . SER C 3 84  ? 130.049 122.534 146.480 1.00 45.63  ? 74  SER B N   1 
ATOM 4459 C CA  . SER C 3 84  ? 129.968 121.810 145.223 1.00 48.01  ? 74  SER B CA  1 
ATOM 4460 C C   . SER C 3 84  ? 131.310 121.144 144.947 1.00 52.63  ? 74  SER B C   1 
ATOM 4461 O O   . SER C 3 84  ? 132.253 121.242 145.739 1.00 56.96  ? 74  SER B O   1 
ATOM 4462 C CB  . SER C 3 84  ? 129.554 122.742 144.082 1.00 56.39  ? 74  SER B CB  1 
ATOM 4463 O OG  . SER C 3 84  ? 130.342 123.917 144.086 1.00 58.86  ? 74  SER B OG  1 
ATOM 4464 N N   . GLN C 3 85  ? 131.389 120.455 143.807 1.00 62.74  ? 75  GLN B N   1 
ATOM 4465 C CA  . GLN C 3 85  ? 132.586 119.702 143.447 1.00 66.13  ? 75  GLN B CA  1 
ATOM 4466 C C   . GLN C 3 85  ? 133.761 120.594 143.068 1.00 71.52  ? 75  GLN B C   1 
ATOM 4467 O O   . GLN C 3 85  ? 134.906 120.135 143.124 1.00 69.80  ? 75  GLN B O   1 
ATOM 4468 C CB  . GLN C 3 85  ? 132.273 118.750 142.293 1.00 66.75  ? 75  GLN B CB  1 
ATOM 4469 C CG  . GLN C 3 85  ? 131.322 117.629 142.651 1.00 67.27  ? 75  GLN B CG  1 
ATOM 4470 C CD  . GLN C 3 85  ? 132.038 116.428 143.232 1.00 70.68  ? 75  GLN B CD  1 
ATOM 4471 O OE1 . GLN C 3 85  ? 132.238 116.328 144.442 1.00 69.80  ? 75  GLN B OE1 1 
ATOM 4472 N NE2 . GLN C 3 85  ? 132.401 115.488 142.367 1.00 69.92  ? 75  GLN B NE2 1 
ATOM 4473 N N   . ASP C 3 86  ? 133.485 121.873 142.773 1.00 63.72  ? 76  ASP B N   1 
ATOM 4474 C CA  . ASP C 3 86  ? 134.521 122.823 142.317 1.00 58.65  ? 76  ASP B CA  1 
ATOM 4475 C C   . ASP C 3 86  ? 135.430 123.242 143.447 1.00 56.26  ? 76  ASP B C   1 
ATOM 4476 O O   . ASP C 3 86  ? 136.364 123.964 143.180 1.00 60.06  ? 76  ASP B O   1 
ATOM 4477 C CB  . ASP C 3 86  ? 133.888 124.104 141.818 1.00 59.18  ? 76  ASP B CB  1 
ATOM 4478 C CG  . ASP C 3 86  ? 132.417 124.266 142.133 1.00 64.09  ? 76  ASP B CG  1 
ATOM 4479 O OD1 . ASP C 3 86  ? 132.058 125.270 142.775 1.00 65.60  ? 76  ASP B OD1 1 
ATOM 4480 O OD2 . ASP C 3 86  ? 131.645 123.406 141.709 1.00 68.45  ? 76  ASP B OD2 1 
ATOM 4481 N N   . GLY C 3 87  ? 135.174 122.782 144.648 1.00 60.75  ? 77  GLY B N   1 
ATOM 4482 C CA  . GLY C 3 87  ? 135.948 123.197 145.796 1.00 64.08  ? 77  GLY B CA  1 
ATOM 4483 C C   . GLY C 3 87  ? 135.577 124.543 146.369 1.00 62.07  ? 77  GLY B C   1 
ATOM 4484 O O   . GLY C 3 87  ? 136.326 125.071 147.199 1.00 67.67  ? 77  GLY B O   1 
ATOM 4485 N N   . LYS C 3 88  ? 134.451 125.117 145.959 1.00 56.37  ? 78  LYS B N   1 
ATOM 4486 C CA  . LYS C 3 88  ? 134.037 126.438 146.401 1.00 61.73  ? 78  LYS B CA  1 
ATOM 4487 C C   . LYS C 3 88  ? 132.887 126.324 147.390 1.00 53.89  ? 78  LYS B C   1 
ATOM 4488 O O   . LYS C 3 88  ? 131.973 125.515 147.207 1.00 54.83  ? 78  LYS B O   1 
ATOM 4489 C CB  . LYS C 3 88  ? 133.615 127.313 145.218 1.00 60.94  ? 78  LYS B CB  1 
ATOM 4490 C CG  . LYS C 3 88  ? 134.742 127.665 144.263 1.00 59.97  ? 78  LYS B CG  1 
ATOM 4491 C CD  . LYS C 3 88  ? 135.778 128.556 144.925 1.00 60.43  ? 78  LYS B CD  1 
ATOM 4492 C CE  . LYS C 3 88  ? 137.012 128.701 144.050 1.00 66.89  ? 78  LYS B CE  1 
ATOM 4493 N NZ  . LYS C 3 88  ? 137.196 127.532 143.144 1.00 65.06  ? 78  LYS B NZ  1 
ATOM 4494 N N   . LEU C 3 89  ? 132.947 127.137 148.439 1.00 36.47  ? 79  LEU B N   1 
ATOM 4495 C CA  . LEU C 3 89  ? 131.881 127.254 149.426 1.00 32.86  ? 79  LEU B CA  1 
ATOM 4496 C C   . LEU C 3 89  ? 131.346 128.676 149.328 1.00 43.53  ? 79  LEU B C   1 
ATOM 4497 O O   . LEU C 3 89  ? 132.010 129.622 149.765 1.00 52.91  ? 79  LEU B O   1 
ATOM 4498 C CB  . LEU C 3 89  ? 132.403 126.951 150.828 1.00 41.29  ? 79  LEU B CB  1 
ATOM 4499 C CG  . LEU C 3 89  ? 131.384 126.929 151.963 1.00 32.33  ? 79  LEU B CG  1 
ATOM 4500 C CD1 . LEU C 3 89  ? 130.238 126.009 151.604 1.00 37.77  ? 79  LEU B CD1 1 
ATOM 4501 C CD2 . LEU C 3 89  ? 132.037 126.504 153.260 1.00 28.69  ? 79  LEU B CD2 1 
ATOM 4502 N N   . ILE C 3 90  ? 130.159 128.830 148.749 1.00 40.50  ? 80  ILE B N   1 
ATOM 4503 C CA  . ILE C 3 90  ? 129.599 130.138 148.428 1.00 35.88  ? 80  ILE B CA  1 
ATOM 4504 C C   . ILE C 3 90  ? 128.485 130.453 149.413 1.00 35.65  ? 80  ILE B C   1 
ATOM 4505 O O   . ILE C 3 90  ? 127.624 129.606 149.678 1.00 53.20  ? 80  ILE B O   1 
ATOM 4506 C CB  . ILE C 3 90  ? 129.075 130.190 146.982 1.00 39.24  ? 80  ILE B CB  1 
ATOM 4507 C CG1 . ILE C 3 90  ? 130.190 129.858 145.993 1.00 45.47  ? 80  ILE B CG1 1 
ATOM 4508 C CG2 . ILE C 3 90  ? 128.495 131.556 146.674 1.00 42.62  ? 80  ILE B CG2 1 
ATOM 4509 C CD1 . ILE C 3 90  ? 129.725 129.817 144.561 1.00 46.35  ? 80  ILE B CD1 1 
ATOM 4510 N N   . ILE C 3 91  ? 128.505 131.667 149.954 1.00 29.07  ? 81  ILE B N   1 
ATOM 4511 C CA  . ILE C 3 91  ? 127.451 132.173 150.826 1.00 30.22  ? 81  ILE B CA  1 
ATOM 4512 C C   . ILE C 3 91  ? 126.651 133.197 150.036 1.00 34.23  ? 81  ILE B C   1 
ATOM 4513 O O   . ILE C 3 91  ? 127.194 134.219 149.602 1.00 45.88  ? 81  ILE B O   1 
ATOM 4514 C CB  . ILE C 3 91  ? 128.023 132.788 152.110 1.00 25.79  ? 81  ILE B CB  1 
ATOM 4515 C CG1 . ILE C 3 91  ? 128.660 131.705 152.976 1.00 34.09  ? 81  ILE B CG1 1 
ATOM 4516 C CG2 . ILE C 3 91  ? 126.939 133.522 152.877 1.00 27.72  ? 81  ILE B CG2 1 
ATOM 4517 C CD1 . ILE C 3 91  ? 129.178 132.216 154.292 1.00 37.68  ? 81  ILE B CD1 1 
ATOM 4518 N N   . TRP C 3 92  ? 125.364 132.927 149.854 1.00 36.32  ? 82  TRP B N   1 
ATOM 4519 C CA  . TRP C 3 92  ? 124.499 133.759 149.033 1.00 41.19  ? 82  TRP B CA  1 
ATOM 4520 C C   . TRP C 3 92  ? 123.686 134.720 149.887 1.00 45.26  ? 82  TRP B C   1 
ATOM 4521 O O   . TRP C 3 92  ? 123.476 134.510 151.083 1.00 48.63  ? 82  TRP B O   1 
ATOM 4522 C CB  . TRP C 3 92  ? 123.545 132.900 148.201 1.00 46.36  ? 82  TRP B CB  1 
ATOM 4523 C CG  . TRP C 3 92  ? 124.202 131.785 147.467 1.00 53.75  ? 82  TRP B CG  1 
ATOM 4524 C CD1 . TRP C 3 92  ? 124.539 130.563 147.965 1.00 56.85  ? 82  TRP B CD1 1 
ATOM 4525 C CD2 . TRP C 3 92  ? 124.584 131.778 146.090 1.00 48.08  ? 82  TRP B CD2 1 
ATOM 4526 N NE1 . TRP C 3 92  ? 125.120 129.797 146.985 1.00 55.00  ? 82  TRP B NE1 1 
ATOM 4527 C CE2 . TRP C 3 92  ? 125.159 130.521 145.823 1.00 44.57  ? 82  TRP B CE2 1 
ATOM 4528 C CE3 . TRP C 3 92  ? 124.502 132.714 145.057 1.00 45.41  ? 82  TRP B CE3 1 
ATOM 4529 C CZ2 . TRP C 3 92  ? 125.647 130.176 144.569 1.00 43.59  ? 82  TRP B CZ2 1 
ATOM 4530 C CZ3 . TRP C 3 92  ? 124.987 132.371 143.813 1.00 53.73  ? 82  TRP B CZ3 1 
ATOM 4531 C CH2 . TRP C 3 92  ? 125.552 131.112 143.579 1.00 51.02  ? 82  TRP B CH2 1 
ATOM 4532 N N   . ASP C 3 93  ? 123.228 135.789 149.245 1.00 46.89  ? 83  ASP B N   1 
ATOM 4533 C CA  . ASP C 3 93  ? 122.189 136.654 149.786 1.00 43.15  ? 83  ASP B CA  1 
ATOM 4534 C C   . ASP C 3 93  ? 120.907 136.307 149.039 1.00 49.35  ? 83  ASP B C   1 
ATOM 4535 O O   . ASP C 3 93  ? 120.742 136.675 147.873 1.00 52.93  ? 83  ASP B O   1 
ATOM 4536 C CB  . ASP C 3 93  ? 122.559 138.126 149.625 1.00 40.35  ? 83  ASP B CB  1 
ATOM 4537 C CG  . ASP C 3 93  ? 121.573 139.054 150.302 1.00 44.44  ? 83  ASP B CG  1 
ATOM 4538 O OD1 . ASP C 3 93  ? 120.751 138.569 151.103 1.00 41.18  ? 83  ASP B OD1 1 
ATOM 4539 O OD2 . ASP C 3 93  ? 121.623 140.273 150.037 1.00 43.60  ? 83  ASP B OD2 1 
ATOM 4540 N N   . SER C 3 94  ? 120.003 135.591 149.709 1.00 42.80  ? 84  SER B N   1 
ATOM 4541 C CA  . SER C 3 94  ? 118.861 134.992 149.028 1.00 37.88  ? 84  SER B CA  1 
ATOM 4542 C C   . SER C 3 94  ? 117.842 136.014 148.540 1.00 50.96  ? 84  SER B C   1 
ATOM 4543 O O   . SER C 3 94  ? 116.944 135.642 147.778 1.00 62.67  ? 84  SER B O   1 
ATOM 4544 C CB  . SER C 3 94  ? 118.178 133.983 149.950 1.00 43.06  ? 84  SER B CB  1 
ATOM 4545 O OG  . SER C 3 94  ? 116.982 133.497 149.374 1.00 47.27  ? 84  SER B OG  1 
ATOM 4546 N N   . TYR C 3 95  ? 117.948 137.276 148.952 1.00 48.95  ? 85  TYR B N   1 
ATOM 4547 C CA  . TYR C 3 95  ? 117.003 138.297 148.510 1.00 43.76  ? 85  TYR B CA  1 
ATOM 4548 C C   . TYR C 3 95  ? 117.444 138.937 147.197 1.00 42.71  ? 85  TYR B C   1 
ATOM 4549 O O   . TYR C 3 95  ? 116.719 138.887 146.199 1.00 48.50  ? 85  TYR B O   1 
ATOM 4550 C CB  . TYR C 3 95  ? 116.836 139.367 149.595 1.00 41.05  ? 85  TYR B CB  1 
ATOM 4551 C CG  . TYR C 3 95  ? 115.880 138.992 150.703 1.00 41.00  ? 85  TYR B CG  1 
ATOM 4552 C CD1 . TYR C 3 95  ? 115.442 137.685 150.860 1.00 44.80  ? 85  TYR B CD1 1 
ATOM 4553 C CD2 . TYR C 3 95  ? 115.419 139.947 151.597 1.00 43.52  ? 85  TYR B CD2 1 
ATOM 4554 C CE1 . TYR C 3 95  ? 114.571 137.341 151.875 1.00 51.89  ? 85  TYR B CE1 1 
ATOM 4555 C CE2 . TYR C 3 95  ? 114.549 139.612 152.614 1.00 41.78  ? 85  TYR B CE2 1 
ATOM 4556 C CZ  . TYR C 3 95  ? 114.128 138.309 152.749 1.00 49.77  ? 85  TYR B CZ  1 
ATOM 4557 O OH  . TYR C 3 95  ? 113.260 137.974 153.761 1.00 52.94  ? 85  TYR B OH  1 
ATOM 4558 N N   . THR C 3 96  ? 118.629 139.540 147.184 1.00 36.16  ? 86  THR B N   1 
ATOM 4559 C CA  . THR C 3 96  ? 119.132 140.250 146.016 1.00 33.69  ? 86  THR B CA  1 
ATOM 4560 C C   . THR C 3 96  ? 120.046 139.403 145.140 1.00 35.82  ? 86  THR B C   1 
ATOM 4561 O O   . THR C 3 96  ? 120.550 139.910 144.133 1.00 40.45  ? 86  THR B O   1 
ATOM 4562 C CB  . THR C 3 96  ? 119.875 141.517 146.448 1.00 36.67  ? 86  THR B CB  1 
ATOM 4563 O OG1 . THR C 3 96  ? 121.165 141.164 146.959 1.00 41.90  ? 86  THR B OG1 1 
ATOM 4564 C CG2 . THR C 3 96  ? 119.093 142.251 147.524 1.00 38.80  ? 86  THR B CG2 1 
ATOM 4565 N N   . THR C 3 97  ? 120.269 138.136 145.494 1.00 43.98  ? 87  THR B N   1 
ATOM 4566 C CA  . THR C 3 97  ? 121.103 137.212 144.721 1.00 46.23  ? 87  THR B CA  1 
ATOM 4567 C C   . THR C 3 97  ? 122.514 137.802 144.564 1.00 44.98  ? 87  THR B C   1 
ATOM 4568 O O   . THR C 3 97  ? 122.948 138.255 143.503 1.00 49.79  ? 87  THR B O   1 
ATOM 4569 C CB  . THR C 3 97  ? 120.414 136.863 143.388 1.00 52.09  ? 87  THR B CB  1 
ATOM 4570 O OG1 . THR C 3 97  ? 119.421 135.863 143.637 1.00 50.00  ? 87  THR B OG1 1 
ATOM 4571 C CG2 . THR C 3 97  ? 121.376 136.233 142.381 1.00 46.00  ? 87  THR B CG2 1 
ATOM 4572 N N   . ASN C 3 98  ? 123.185 137.884 145.709 1.00 38.79  ? 88  ASN B N   1 
ATOM 4573 C CA  . ASN C 3 98  ? 124.556 138.366 145.779 1.00 42.40  ? 88  ASN B CA  1 
ATOM 4574 C C   . ASN C 3 98  ? 125.411 137.348 146.518 1.00 49.56  ? 88  ASN B C   1 
ATOM 4575 O O   . ASN C 3 98  ? 124.945 136.677 147.443 1.00 53.78  ? 88  ASN B O   1 
ATOM 4576 C CB  . ASN C 3 98  ? 124.650 139.726 146.485 1.00 43.56  ? 88  ASN B CB  1 
ATOM 4577 C CG  . ASN C 3 98  ? 124.098 140.860 145.646 1.00 49.30  ? 88  ASN B CG  1 
ATOM 4578 O OD1 . ASN C 3 98  ? 123.134 141.519 146.031 1.00 49.92  ? 88  ASN B OD1 1 
ATOM 4579 N ND2 . ASN C 3 98  ? 124.712 141.096 144.494 1.00 50.81  ? 88  ASN B ND2 1 
ATOM 4580 N N   . LYS C 3 99  ? 126.668 137.239 146.100 1.00 50.21  ? 89  LYS B N   1 
ATOM 4581 C CA  . LYS C 3 99  ? 127.618 136.313 146.713 1.00 41.27  ? 89  LYS B CA  1 
ATOM 4582 C C   . LYS C 3 99  ? 128.361 137.056 147.816 1.00 42.60  ? 89  LYS B C   1 
ATOM 4583 O O   . LYS C 3 99  ? 129.262 137.853 147.547 1.00 51.95  ? 89  LYS B O   1 
ATOM 4584 C CB  . LYS C 3 99  ? 128.577 135.759 145.667 1.00 41.93  ? 89  LYS B CB  1 
ATOM 4585 C CG  . LYS C 3 99  ? 127.891 134.993 144.555 1.00 44.14  ? 89  LYS B CG  1 
ATOM 4586 C CD  . LYS C 3 99  ? 128.865 134.641 143.448 1.00 46.63  ? 89  LYS B CD  1 
ATOM 4587 C CE  . LYS C 3 99  ? 128.193 133.797 142.381 1.00 49.07  ? 89  LYS B CE  1 
ATOM 4588 N NZ  . LYS C 3 99  ? 127.092 134.537 141.709 1.00 42.30  ? 89  LYS B NZ  1 
ATOM 4589 N N   . VAL C 3 100 ? 127.978 136.798 149.066 1.00 32.47  ? 90  VAL B N   1 
ATOM 4590 C CA  . VAL C 3 100 ? 128.616 137.476 150.190 1.00 35.62  ? 90  VAL B CA  1 
ATOM 4591 C C   . VAL C 3 100 ? 130.044 136.975 150.376 1.00 44.40  ? 90  VAL B C   1 
ATOM 4592 O O   . VAL C 3 100 ? 130.976 137.764 150.565 1.00 48.93  ? 90  VAL B O   1 
ATOM 4593 C CB  . VAL C 3 100 ? 127.780 137.293 151.470 1.00 37.09  ? 90  VAL B CB  1 
ATOM 4594 C CG1 . VAL C 3 100 ? 128.382 138.086 152.613 1.00 41.43  ? 90  VAL B CG1 1 
ATOM 4595 C CG2 . VAL C 3 100 ? 126.345 137.715 151.227 1.00 36.49  ? 90  VAL B CG2 1 
ATOM 4596 N N   . HIS C 3 101 ? 130.239 135.658 150.318 1.00 33.34  ? 91  HIS B N   1 
ATOM 4597 C CA  . HIS C 3 101 ? 131.543 135.055 150.547 1.00 26.24  ? 91  HIS B CA  1 
ATOM 4598 C C   . HIS C 3 101 ? 131.791 133.958 149.523 1.00 33.22  ? 91  HIS B C   1 
ATOM 4599 O O   . HIS C 3 101 ? 130.860 133.395 148.944 1.00 51.61  ? 91  HIS B O   1 
ATOM 4600 C CB  . HIS C 3 101 ? 131.660 134.469 151.961 1.00 32.62  ? 91  HIS B CB  1 
ATOM 4601 C CG  . HIS C 3 101 ? 131.721 135.498 153.045 1.00 27.25  ? 91  HIS B CG  1 
ATOM 4602 N ND1 . HIS C 3 101 ? 132.837 136.272 153.275 1.00 32.46  ? 91  HIS B ND1 1 
ATOM 4603 C CD2 . HIS C 3 101 ? 130.806 135.872 153.970 1.00 27.57  ? 91  HIS B CD2 1 
ATOM 4604 C CE1 . HIS C 3 101 ? 132.606 137.082 154.293 1.00 40.18  ? 91  HIS B CE1 1 
ATOM 4605 N NE2 . HIS C 3 101 ? 131.380 136.860 154.732 1.00 32.82  ? 91  HIS B NE2 1 
ATOM 4606 N N   . ALA C 3 102 ? 133.070 133.660 149.310 1.00 33.29  ? 92  ALA B N   1 
ATOM 4607 C CA  . ALA C 3 102 ? 133.492 132.541 148.471 1.00 34.72  ? 92  ALA B CA  1 
ATOM 4608 C C   . ALA C 3 102 ? 134.693 131.895 149.145 1.00 44.94  ? 92  ALA B C   1 
ATOM 4609 O O   . ALA C 3 102 ? 135.804 132.429 149.080 1.00 48.85  ? 92  ALA B O   1 
ATOM 4610 C CB  . ALA C 3 102 ? 133.834 132.998 147.054 1.00 36.16  ? 92  ALA B CB  1 
ATOM 4611 N N   . ILE C 3 103 ? 134.471 130.757 149.788 1.00 37.93  ? 93  ILE B N   1 
ATOM 4612 C CA  . ILE C 3 103 ? 135.483 130.090 150.603 1.00 38.82  ? 93  ILE B CA  1 
ATOM 4613 C C   . ILE C 3 103 ? 136.036 128.912 149.811 1.00 42.91  ? 93  ILE B C   1 
ATOM 4614 O O   . ILE C 3 103 ? 135.260 128.024 149.426 1.00 49.42  ? 93  ILE B O   1 
ATOM 4615 C CB  . ILE C 3 103 ? 134.904 129.627 151.947 1.00 37.38  ? 93  ILE B CB  1 
ATOM 4616 C CG1 . ILE C 3 103 ? 134.094 130.753 152.590 1.00 36.72  ? 93  ILE B CG1 1 
ATOM 4617 C CG2 . ILE C 3 103 ? 136.014 129.174 152.868 1.00 37.25  ? 93  ILE B CG2 1 
ATOM 4618 C CD1 . ILE C 3 103 ? 133.033 130.273 153.550 1.00 41.45  ? 93  ILE B CD1 1 
ATOM 4619 N N   . PRO C 3 104 ? 137.343 128.855 149.547 1.00 49.94  ? 94  PRO B N   1 
ATOM 4620 C CA  . PRO C 3 104 ? 137.906 127.718 148.812 1.00 53.96  ? 94  PRO B CA  1 
ATOM 4621 C C   . PRO C 3 104 ? 138.308 126.547 149.699 1.00 59.48  ? 94  PRO B C   1 
ATOM 4622 O O   . PRO C 3 104 ? 139.121 126.688 150.618 1.00 53.62  ? 94  PRO B O   1 
ATOM 4623 C CB  . PRO C 3 104 ? 139.118 128.360 148.113 1.00 55.90  ? 94  PRO B CB  1 
ATOM 4624 C CG  . PRO C 3 104 ? 139.277 129.776 148.850 1.00 55.99  ? 94  PRO B CG  1 
ATOM 4625 C CD  . PRO C 3 104 ? 138.472 129.609 150.095 1.00 55.51  ? 94  PRO B CD  1 
ATOM 4626 N N   . LEU C 3 105 ? 137.749 125.376 149.412 1.00 63.53  ? 95  LEU B N   1 
ATOM 4627 C CA  . LEU C 3 105 ? 138.014 124.186 150.205 1.00 53.24  ? 95  LEU B CA  1 
ATOM 4628 C C   . LEU C 3 105 ? 139.349 123.561 149.820 1.00 61.17  ? 95  LEU B C   1 
ATOM 4629 O O   . LEU C 3 105 ? 139.817 123.690 148.686 1.00 64.35  ? 95  LEU B O   1 
ATOM 4630 C CB  . LEU C 3 105 ? 136.892 123.166 150.021 1.00 54.37  ? 95  LEU B CB  1 
ATOM 4631 C CG  . LEU C 3 105 ? 135.478 123.712 150.209 1.00 57.71  ? 95  LEU B CG  1 
ATOM 4632 C CD1 . LEU C 3 105 ? 134.478 122.852 149.468 1.00 55.11  ? 95  LEU B CD1 1 
ATOM 4633 C CD2 . LEU C 3 105 ? 135.129 123.787 151.681 1.00 60.45  ? 95  LEU B CD2 1 
ATOM 4634 N N   . ARG C 3 106 ? 139.963 122.874 150.786 1.00 76.52  ? 96  ARG B N   1 
ATOM 4635 C CA  . ARG C 3 106 ? 141.205 122.161 150.504 1.00 77.21  ? 96  ARG B CA  1 
ATOM 4636 C C   . ARG C 3 106 ? 140.952 120.935 149.636 1.00 76.78  ? 96  ARG B C   1 
ATOM 4637 O O   . ARG C 3 106 ? 141.755 120.619 148.750 1.00 77.42  ? 96  ARG B O   1 
ATOM 4638 C CB  . ARG C 3 106 ? 141.893 121.762 151.808 1.00 77.50  ? 96  ARG B CB  1 
ATOM 4639 C CG  . ARG C 3 106 ? 141.747 122.779 152.926 1.00 78.31  ? 96  ARG B CG  1 
ATOM 4640 C CD  . ARG C 3 106 ? 142.670 122.446 154.087 1.00 78.87  ? 96  ARG B CD  1 
ATOM 4641 N NE  . ARG C 3 106 ? 144.040 122.220 153.644 1.00 80.70  ? 96  ARG B NE  1 
ATOM 4642 C CZ  . ARG C 3 106 ? 145.001 121.717 154.407 1.00 81.29  ? 96  ARG B CZ  1 
ATOM 4643 N NH1 . ARG C 3 106 ? 144.775 121.373 155.665 1.00 79.38  ? 96  ARG B NH1 1 
ATOM 4644 N NH2 . ARG C 3 106 ? 146.218 121.554 153.896 1.00 80.40  ? 96  ARG B NH2 1 
ATOM 4645 N N   . SER C 3 107 ? 139.848 120.233 149.873 1.00 70.59  ? 97  SER B N   1 
ATOM 4646 C CA  . SER C 3 107 ? 139.484 119.046 149.112 1.00 68.76  ? 97  SER B CA  1 
ATOM 4647 C C   . SER C 3 107 ? 138.202 119.315 148.338 1.00 65.27  ? 97  SER B C   1 
ATOM 4648 O O   . SER C 3 107 ? 137.212 119.780 148.911 1.00 70.43  ? 97  SER B O   1 
ATOM 4649 C CB  . SER C 3 107 ? 139.299 117.838 150.032 1.00 68.09  ? 97  SER B CB  1 
ATOM 4650 O OG  . SER C 3 107 ? 137.988 117.804 150.569 1.00 63.54  ? 97  SER B OG  1 
ATOM 4651 N N   . SER C 3 108 ? 138.223 119.015 147.039 1.00 64.77  ? 98  SER B N   1 
ATOM 4652 C CA  . SER C 3 108 ? 137.067 119.260 146.187 1.00 67.73  ? 98  SER B CA  1 
ATOM 4653 C C   . SER C 3 108 ? 135.914 118.300 146.453 1.00 68.80  ? 98  SER B C   1 
ATOM 4654 O O   . SER C 3 108 ? 134.812 118.535 145.947 1.00 65.73  ? 98  SER B O   1 
ATOM 4655 C CB  . SER C 3 108 ? 137.477 119.173 144.716 1.00 69.84  ? 98  SER B CB  1 
ATOM 4656 O OG  . SER C 3 108 ? 138.785 119.680 144.518 1.00 74.43  ? 98  SER B OG  1 
ATOM 4657 N N   . TRP C 3 109 ? 136.134 117.238 147.226 1.00 63.04  ? 99  TRP B N   1 
ATOM 4658 C CA  . TRP C 3 109 ? 135.117 116.218 147.483 1.00 62.96  ? 99  TRP B CA  1 
ATOM 4659 C C   . TRP C 3 109 ? 134.441 116.555 148.810 1.00 61.50  ? 99  TRP B C   1 
ATOM 4660 O O   . TRP C 3 109 ? 134.917 116.184 149.883 1.00 65.50  ? 99  TRP B O   1 
ATOM 4661 C CB  . TRP C 3 109 ? 135.741 114.827 147.500 1.00 67.09  ? 99  TRP B CB  1 
ATOM 4662 C CG  . TRP C 3 109 ? 136.731 114.588 146.392 1.00 60.18  ? 99  TRP B CG  1 
ATOM 4663 C CD1 . TRP C 3 109 ? 138.048 114.259 146.528 1.00 51.70  ? 99  TRP B CD1 1 
ATOM 4664 C CD2 . TRP C 3 109 ? 136.481 114.654 144.983 1.00 58.58  ? 99  TRP B CD2 1 
ATOM 4665 N NE1 . TRP C 3 109 ? 138.633 114.122 145.295 1.00 55.16  ? 99  TRP B NE1 1 
ATOM 4666 C CE2 . TRP C 3 109 ? 137.691 114.358 144.329 1.00 58.73  ? 99  TRP B CE2 1 
ATOM 4667 C CE3 . TRP C 3 109 ? 135.351 114.937 144.211 1.00 62.49  ? 99  TRP B CE3 1 
ATOM 4668 C CZ2 . TRP C 3 109 ? 137.803 114.336 142.943 1.00 65.22  ? 99  TRP B CZ2 1 
ATOM 4669 C CZ3 . TRP C 3 109 ? 135.466 114.915 142.836 1.00 63.25  ? 99  TRP B CZ3 1 
ATOM 4670 C CH2 . TRP C 3 109 ? 136.681 114.617 142.216 1.00 63.61  ? 99  TRP B CH2 1 
ATOM 4671 N N   . VAL C 3 110 ? 133.323 117.274 148.731 1.00 51.66  ? 100 VAL B N   1 
ATOM 4672 C CA  . VAL C 3 110 ? 132.573 117.721 149.900 1.00 50.09  ? 100 VAL B CA  1 
ATOM 4673 C C   . VAL C 3 110 ? 131.110 117.336 149.722 1.00 54.91  ? 100 VAL B C   1 
ATOM 4674 O O   . VAL C 3 110 ? 130.542 117.528 148.641 1.00 64.31  ? 100 VAL B O   1 
ATOM 4675 C CB  . VAL C 3 110 ? 132.717 119.236 150.120 1.00 53.09  ? 100 VAL B CB  1 
ATOM 4676 C CG1 . VAL C 3 110 ? 132.434 119.989 148.833 1.00 54.01  ? 100 VAL B CG1 1 
ATOM 4677 C CG2 . VAL C 3 110 ? 131.778 119.687 151.208 1.00 55.54  ? 100 VAL B CG2 1 
ATOM 4678 N N   . MET C 3 111 ? 130.506 116.779 150.773 1.00 53.98  ? 101 MET B N   1 
ATOM 4679 C CA  . MET C 3 111 ? 129.137 116.288 150.698 1.00 53.26  ? 101 MET B CA  1 
ATOM 4680 C C   . MET C 3 111 ? 128.177 116.932 151.692 1.00 59.25  ? 101 MET B C   1 
ATOM 4681 O O   . MET C 3 111 ? 126.976 116.650 151.630 1.00 69.61  ? 101 MET B O   1 
ATOM 4682 C CB  . MET C 3 111 ? 129.125 114.768 150.895 1.00 48.48  ? 101 MET B CB  1 
ATOM 4683 C CG  . MET C 3 111 ? 130.137 114.031 150.034 1.00 54.48  ? 101 MET B CG  1 
ATOM 4684 S SD  . MET C 3 111 ? 130.417 112.330 150.556 1.00 74.06  ? 101 MET B SD  1 
ATOM 4685 C CE  . MET C 3 111 ? 128.766 111.840 151.038 1.00 57.69  ? 101 MET B CE  1 
ATOM 4686 N N   . THR C 3 112 ? 128.651 117.773 152.610 1.00 46.07  ? 102 THR B N   1 
ATOM 4687 C CA  . THR C 3 112 ? 127.738 118.278 153.631 1.00 41.45  ? 102 THR B CA  1 
ATOM 4688 C C   . THR C 3 112 ? 128.069 119.670 154.171 1.00 44.44  ? 102 THR B C   1 
ATOM 4689 O O   . THR C 3 112 ? 128.973 119.837 154.994 1.00 51.17  ? 102 THR B O   1 
ATOM 4690 C CB  . THR C 3 112 ? 127.624 117.260 154.771 1.00 43.71  ? 102 THR B CB  1 
ATOM 4691 O OG1 . THR C 3 112 ? 126.713 117.750 155.760 1.00 52.17  ? 102 THR B OG1 1 
ATOM 4692 C CG2 . THR C 3 112 ? 128.973 116.918 155.389 1.00 42.40  ? 102 THR B CG2 1 
ATOM 4693 N N   . CYS C 3 113 ? 127.355 120.683 153.682 1.00 48.07  ? 103 CYS B N   1 
ATOM 4694 C CA  . CYS C 3 113 ? 127.366 121.998 154.310 1.00 36.53  ? 103 CYS B CA  1 
ATOM 4695 C C   . CYS C 3 113 ? 126.671 121.969 155.671 1.00 45.58  ? 103 CYS B C   1 
ATOM 4696 O O   . CYS C 3 113 ? 125.902 121.058 155.996 1.00 47.95  ? 103 CYS B O   1 
ATOM 4697 C CB  . CYS C 3 113 ? 126.666 123.036 153.436 1.00 34.61  ? 103 CYS B CB  1 
ATOM 4698 S SG  . CYS C 3 113 ? 127.437 123.394 151.869 1.00 64.67  ? 103 CYS B SG  1 
ATOM 4699 N N   . ALA C 3 114 ? 126.960 122.995 156.471 1.00 40.75  ? 104 ALA B N   1 
ATOM 4700 C CA  . ALA C 3 114 ? 126.245 123.273 157.709 1.00 37.45  ? 104 ALA B CA  1 
ATOM 4701 C C   . ALA C 3 114 ? 126.439 124.745 158.038 1.00 41.80  ? 104 ALA B C   1 
ATOM 4702 O O   . ALA C 3 114 ? 127.541 125.275 157.888 1.00 55.78  ? 104 ALA B O   1 
ATOM 4703 C CB  . ALA C 3 114 ? 126.740 122.399 158.865 1.00 39.57  ? 104 ALA B CB  1 
ATOM 4704 N N   . TYR C 3 115 ? 125.374 125.398 158.493 1.00 24.45  ? 105 TYR B N   1 
ATOM 4705 C CA  . TYR C 3 115 ? 125.426 126.806 158.856 1.00 17.73  ? 105 TYR B CA  1 
ATOM 4706 C C   . TYR C 3 115 ? 125.148 126.940 160.345 1.00 28.69  ? 105 TYR B C   1 
ATOM 4707 O O   . TYR C 3 115 ? 124.217 126.319 160.868 1.00 45.22  ? 105 TYR B O   1 
ATOM 4708 C CB  . TYR C 3 115 ? 124.408 127.631 158.056 1.00 20.69  ? 105 TYR B CB  1 
ATOM 4709 C CG  . TYR C 3 115 ? 124.829 129.065 157.827 1.00 25.94  ? 105 TYR B CG  1 
ATOM 4710 C CD1 . TYR C 3 115 ? 124.598 130.036 158.787 1.00 28.81  ? 105 TYR B CD1 1 
ATOM 4711 C CD2 . TYR C 3 115 ? 125.436 129.452 156.642 1.00 35.80  ? 105 TYR B CD2 1 
ATOM 4712 C CE1 . TYR C 3 115 ? 124.981 131.343 158.583 1.00 23.48  ? 105 TYR B CE1 1 
ATOM 4713 C CE2 . TYR C 3 115 ? 125.818 130.761 156.427 1.00 25.55  ? 105 TYR B CE2 1 
ATOM 4714 C CZ  . TYR C 3 115 ? 125.587 131.701 157.403 1.00 16.52  ? 105 TYR B CZ  1 
ATOM 4715 O OH  . TYR C 3 115 ? 125.961 133.008 157.207 1.00 28.02  ? 105 TYR B OH  1 
ATOM 4716 N N   . ALA C 3 116 ? 125.959 127.740 161.030 1.00 37.48  ? 106 ALA B N   1 
ATOM 4717 C CA  . ALA C 3 116 ? 125.785 127.903 162.462 1.00 37.55  ? 106 ALA B CA  1 
ATOM 4718 C C   . ALA C 3 116 ? 124.492 128.661 162.756 1.00 44.86  ? 106 ALA B C   1 
ATOM 4719 O O   . ALA C 3 116 ? 124.059 129.498 161.960 1.00 51.71  ? 106 ALA B O   1 
ATOM 4720 C CB  . ALA C 3 116 ? 126.972 128.643 163.072 1.00 45.66  ? 106 ALA B CB  1 
ATOM 4721 N N   . PRO C 3 117 ? 123.843 128.367 163.884 1.00 46.52  ? 107 PRO B N   1 
ATOM 4722 C CA  . PRO C 3 117 ? 122.621 129.106 164.236 1.00 41.41  ? 107 PRO B CA  1 
ATOM 4723 C C   . PRO C 3 117 ? 122.852 130.592 164.432 1.00 45.02  ? 107 PRO B C   1 
ATOM 4724 O O   . PRO C 3 117 ? 121.957 131.393 164.137 1.00 49.92  ? 107 PRO B O   1 
ATOM 4725 C CB  . PRO C 3 117 ? 122.162 128.428 165.535 1.00 40.84  ? 107 PRO B CB  1 
ATOM 4726 C CG  . PRO C 3 117 ? 122.907 127.131 165.593 1.00 50.51  ? 107 PRO B CG  1 
ATOM 4727 C CD  . PRO C 3 117 ? 124.204 127.379 164.910 1.00 55.32  ? 107 PRO B CD  1 
ATOM 4728 N N   . SER C 3 118 ? 124.024 130.988 164.922 1.00 48.27  ? 108 SER B N   1 
ATOM 4729 C CA  . SER C 3 118 ? 124.321 132.392 165.163 1.00 47.30  ? 108 SER B CA  1 
ATOM 4730 C C   . SER C 3 118 ? 124.886 133.103 163.941 1.00 45.23  ? 108 SER B C   1 
ATOM 4731 O O   . SER C 3 118 ? 125.036 134.328 163.974 1.00 54.79  ? 108 SER B O   1 
ATOM 4732 C CB  . SER C 3 118 ? 125.304 132.531 166.328 1.00 48.72  ? 108 SER B CB  1 
ATOM 4733 O OG  . SER C 3 118 ? 126.571 131.996 165.989 1.00 44.20  ? 108 SER B OG  1 
ATOM 4734 N N   . GLY C 3 119 ? 125.202 132.374 162.874 1.00 39.05  ? 109 GLY B N   1 
ATOM 4735 C CA  . GLY C 3 119 ? 125.739 132.973 161.674 1.00 39.00  ? 109 GLY B CA  1 
ATOM 4736 C C   . GLY C 3 119 ? 127.213 133.304 161.720 1.00 39.77  ? 109 GLY B C   1 
ATOM 4737 O O   . GLY C 3 119 ? 127.731 133.874 160.751 1.00 47.23  ? 109 GLY B O   1 
ATOM 4738 N N   . ASN C 3 120 ? 127.908 132.970 162.808 1.00 44.02  ? 110 ASN B N   1 
ATOM 4739 C CA  . ASN C 3 120 ? 129.326 133.294 162.909 1.00 41.91  ? 110 ASN B CA  1 
ATOM 4740 C C   . ASN C 3 120 ? 130.190 132.290 162.156 1.00 41.31  ? 110 ASN B C   1 
ATOM 4741 O O   . ASN C 3 120 ? 131.143 132.680 161.474 1.00 49.45  ? 110 ASN B O   1 
ATOM 4742 C CB  . ASN C 3 120 ? 129.748 133.356 164.377 1.00 49.60  ? 110 ASN B CB  1 
ATOM 4743 C CG  . ASN C 3 120 ? 129.276 134.619 165.068 1.00 57.06  ? 110 ASN B CG  1 
ATOM 4744 O OD1 . ASN C 3 120 ? 129.833 135.697 164.864 1.00 58.43  ? 110 ASN B OD1 1 
ATOM 4745 N ND2 . ASN C 3 120 ? 128.244 134.491 165.893 1.00 50.64  ? 110 ASN B ND2 1 
ATOM 4746 N N   . TYR C 3 121 ? 129.878 131.003 162.265 1.00 44.40  ? 111 TYR B N   1 
ATOM 4747 C CA  . TYR C 3 121 ? 130.683 129.950 161.670 1.00 41.52  ? 111 TYR B CA  1 
ATOM 4748 C C   . TYR C 3 121 ? 129.904 129.228 160.579 1.00 41.98  ? 111 TYR B C   1 
ATOM 4749 O O   . TYR C 3 121 ? 128.680 129.340 160.476 1.00 46.32  ? 111 TYR B O   1 
ATOM 4750 C CB  . TYR C 3 121 ? 131.140 128.938 162.728 1.00 41.61  ? 111 TYR B CB  1 
ATOM 4751 C CG  . TYR C 3 121 ? 131.914 129.547 163.872 1.00 48.24  ? 111 TYR B CG  1 
ATOM 4752 C CD1 . TYR C 3 121 ? 133.294 129.671 163.813 1.00 52.90  ? 111 TYR B CD1 1 
ATOM 4753 C CD2 . TYR C 3 121 ? 131.266 129.995 165.013 1.00 50.01  ? 111 TYR B CD2 1 
ATOM 4754 C CE1 . TYR C 3 121 ? 134.007 130.228 164.856 1.00 52.39  ? 111 TYR B CE1 1 
ATOM 4755 C CE2 . TYR C 3 121 ? 131.969 130.553 166.061 1.00 54.73  ? 111 TYR B CE2 1 
ATOM 4756 C CZ  . TYR C 3 121 ? 133.338 130.667 165.978 1.00 51.92  ? 111 TYR B CZ  1 
ATOM 4757 O OH  . TYR C 3 121 ? 134.039 131.223 167.022 1.00 50.96  ? 111 TYR B OH  1 
ATOM 4758 N N   . VAL C 3 122 ? 130.641 128.497 159.748 1.00 39.86  ? 112 VAL B N   1 
ATOM 4759 C CA  . VAL C 3 122 ? 130.050 127.597 158.766 1.00 35.31  ? 112 VAL B CA  1 
ATOM 4760 C C   . VAL C 3 122 ? 130.975 126.401 158.582 1.00 38.70  ? 112 VAL B C   1 
ATOM 4761 O O   . VAL C 3 122 ? 132.123 126.551 158.151 1.00 55.45  ? 112 VAL B O   1 
ATOM 4762 C CB  . VAL C 3 122 ? 129.777 128.322 157.434 1.00 33.11  ? 112 VAL B CB  1 
ATOM 4763 C CG1 . VAL C 3 122 ? 130.986 129.116 156.993 1.00 42.30  ? 112 VAL B CG1 1 
ATOM 4764 C CG2 . VAL C 3 122 ? 129.406 127.326 156.367 1.00 36.74  ? 112 VAL B CG2 1 
ATOM 4765 N N   . ALA C 3 123 ? 130.496 125.209 158.925 1.00 26.74  ? 113 ALA B N   1 
ATOM 4766 C CA  . ALA C 3 123 ? 131.303 124.008 158.779 1.00 30.96  ? 113 ALA B CA  1 
ATOM 4767 C C   . ALA C 3 123 ? 131.032 123.347 157.437 1.00 31.73  ? 113 ALA B C   1 
ATOM 4768 O O   . ALA C 3 123 ? 129.927 123.409 156.895 1.00 44.41  ? 113 ALA B O   1 
ATOM 4769 C CB  . ALA C 3 123 ? 131.029 123.019 159.911 1.00 41.11  ? 113 ALA B CB  1 
ATOM 4770 N N   . CYS C 3 124 ? 132.063 122.702 156.901 1.00 42.65  ? 114 CYS B N   1 
ATOM 4771 C CA  . CYS C 3 124 ? 131.930 122.102 155.583 1.00 43.69  ? 114 CYS B CA  1 
ATOM 4772 C C   . CYS C 3 124 ? 132.919 120.958 155.392 1.00 43.98  ? 114 CYS B C   1 
ATOM 4773 O O   . CYS C 3 124 ? 134.087 121.191 155.071 1.00 51.49  ? 114 CYS B O   1 
ATOM 4774 C CB  . CYS C 3 124 ? 132.130 123.184 154.521 1.00 53.85  ? 114 CYS B CB  1 
ATOM 4775 S SG  . CYS C 3 124 ? 131.948 122.652 152.820 1.00 78.65  ? 114 CYS B SG  1 
ATOM 4776 N N   . GLY C 3 125 ? 132.456 119.716 155.558 1.00 33.38  ? 115 GLY B N   1 
ATOM 4777 C CA  . GLY C 3 125 ? 133.304 118.552 155.444 1.00 43.47  ? 115 GLY B CA  1 
ATOM 4778 C C   . GLY C 3 125 ? 132.776 117.583 154.397 1.00 47.59  ? 115 GLY B C   1 
ATOM 4779 O O   . GLY C 3 125 ? 131.692 117.767 153.834 1.00 58.65  ? 115 GLY B O   1 
ATOM 4780 N N   . GLY C 3 126 ? 133.554 116.534 154.147 1.00 41.47  ? 116 GLY B N   1 
ATOM 4781 C CA  . GLY C 3 126 ? 133.163 115.571 153.137 1.00 45.66  ? 116 GLY B CA  1 
ATOM 4782 C C   . GLY C 3 126 ? 134.030 114.334 153.042 1.00 53.02  ? 116 GLY B C   1 
ATOM 4783 O O   . GLY C 3 126 ? 134.450 113.777 154.059 1.00 55.86  ? 116 GLY B O   1 
ATOM 4784 N N   . LEU C 3 127 ? 134.304 113.901 151.808 1.00 60.24  ? 117 LEU B N   1 
ATOM 4785 C CA  . LEU C 3 127 ? 135.008 112.645 151.570 1.00 53.81  ? 117 LEU B CA  1 
ATOM 4786 C C   . LEU C 3 127 ? 136.412 112.633 152.158 1.00 52.62  ? 117 LEU B C   1 
ATOM 4787 O O   . LEU C 3 127 ? 136.961 111.553 152.398 1.00 51.31  ? 117 LEU B O   1 
ATOM 4788 C CB  . LEU C 3 127 ? 135.080 112.367 150.067 1.00 50.33  ? 117 LEU B CB  1 
ATOM 4789 C CG  . LEU C 3 127 ? 134.277 111.186 149.524 1.00 55.12  ? 117 LEU B CG  1 
ATOM 4790 C CD1 . LEU C 3 127 ? 134.313 111.166 148.006 1.00 52.19  ? 117 LEU B CD1 1 
ATOM 4791 C CD2 . LEU C 3 127 ? 134.815 109.887 150.086 1.00 64.52  ? 117 LEU B CD2 1 
ATOM 4792 N N   . ASP C 3 128 ? 137.004 113.799 152.398 1.00 59.44  ? 118 ASP B N   1 
ATOM 4793 C CA  . ASP C 3 128 ? 138.371 113.896 152.891 1.00 58.55  ? 118 ASP B CA  1 
ATOM 4794 C C   . ASP C 3 128 ? 138.491 113.644 154.394 1.00 59.11  ? 118 ASP B C   1 
ATOM 4795 O O   . ASP C 3 128 ? 139.559 113.893 154.964 1.00 57.46  ? 118 ASP B O   1 
ATOM 4796 C CB  . ASP C 3 128 ? 138.958 115.257 152.489 1.00 59.94  ? 118 ASP B CB  1 
ATOM 4797 C CG  . ASP C 3 128 ? 138.517 116.391 153.394 1.00 68.66  ? 118 ASP B CG  1 
ATOM 4798 O OD1 . ASP C 3 128 ? 139.000 116.481 154.536 1.00 71.24  ? 118 ASP B OD1 1 
ATOM 4799 O OD2 . ASP C 3 128 ? 137.675 117.202 152.953 1.00 66.47  ? 118 ASP B OD2 1 
ATOM 4800 N N   . ASN C 3 129 ? 137.427 113.156 155.032 1.00 55.38  ? 119 ASN B N   1 
ATOM 4801 C CA  . ASN C 3 129 ? 137.382 112.547 156.364 1.00 52.36  ? 119 ASN B CA  1 
ATOM 4802 C C   . ASN C 3 129 ? 137.409 113.530 157.533 1.00 59.41  ? 119 ASN B C   1 
ATOM 4803 O O   . ASN C 3 129 ? 137.320 113.074 158.679 1.00 59.15  ? 119 ASN B O   1 
ATOM 4804 C CB  . ASN C 3 129 ? 138.521 111.537 156.584 1.00 57.19  ? 119 ASN B CB  1 
ATOM 4805 C CG  . ASN C 3 129 ? 138.163 110.145 156.114 1.00 61.94  ? 119 ASN B CG  1 
ATOM 4806 O OD1 . ASN C 3 129 ? 137.148 109.585 156.519 1.00 55.01  ? 119 ASN B OD1 1 
ATOM 4807 N ND2 . ASN C 3 129 ? 139.000 109.576 155.256 1.00 70.25  ? 119 ASN B ND2 1 
ATOM 4808 N N   . ILE C 3 130 ? 137.521 114.838 157.311 1.00 60.28  ? 120 ILE B N   1 
ATOM 4809 C CA  . ILE C 3 130 ? 137.550 115.784 158.419 1.00 55.67  ? 120 ILE B CA  1 
ATOM 4810 C C   . ILE C 3 130 ? 136.497 116.858 158.192 1.00 52.34  ? 120 ILE B C   1 
ATOM 4811 O O   . ILE C 3 130 ? 136.137 117.175 157.054 1.00 57.24  ? 120 ILE B O   1 
ATOM 4812 C CB  . ILE C 3 130 ? 138.942 116.428 158.620 1.00 54.11  ? 120 ILE B CB  1 
ATOM 4813 C CG1 . ILE C 3 130 ? 139.335 117.267 157.407 1.00 54.15  ? 120 ILE B CG1 1 
ATOM 4814 C CG2 . ILE C 3 130 ? 139.989 115.360 158.900 1.00 55.48  ? 120 ILE B CG2 1 
ATOM 4815 C CD1 . ILE C 3 130 ? 140.820 117.522 157.286 1.00 60.79  ? 120 ILE B CD1 1 
ATOM 4816 N N   . CYS C 3 131 ? 135.998 117.414 159.294 1.00 51.59  ? 121 CYS B N   1 
ATOM 4817 C CA  . CYS C 3 131 ? 134.966 118.448 159.272 1.00 51.13  ? 121 CYS B CA  1 
ATOM 4818 C C   . CYS C 3 131 ? 135.640 119.803 159.449 1.00 54.10  ? 121 CYS B C   1 
ATOM 4819 O O   . CYS C 3 131 ? 135.891 120.241 160.574 1.00 59.68  ? 121 CYS B O   1 
ATOM 4820 C CB  . CYS C 3 131 ? 133.931 118.198 160.364 1.00 50.91  ? 121 CYS B CB  1 
ATOM 4821 S SG  . CYS C 3 131 ? 132.738 119.532 160.590 1.00 71.85  ? 121 CYS B SG  1 
ATOM 4822 N N   . SER C 3 132 ? 135.934 120.468 158.336 1.00 45.27  ? 122 SER B N   1 
ATOM 4823 C CA  . SER C 3 132 ? 136.538 121.791 158.397 1.00 35.57  ? 122 SER B CA  1 
ATOM 4824 C C   . SER C 3 132 ? 135.509 122.811 158.865 1.00 46.60  ? 122 SER B C   1 
ATOM 4825 O O   . SER C 3 132 ? 134.368 122.818 158.394 1.00 64.54  ? 122 SER B O   1 
ATOM 4826 C CB  . SER C 3 132 ? 137.094 122.184 157.031 1.00 45.94  ? 122 SER B CB  1 
ATOM 4827 O OG  . SER C 3 132 ? 137.991 121.202 156.544 1.00 60.50  ? 122 SER B OG  1 
ATOM 4828 N N   . ILE C 3 133 ? 135.911 123.675 159.792 1.00 46.80  ? 123 ILE B N   1 
ATOM 4829 C CA  . ILE C 3 133 ? 135.040 124.699 160.355 1.00 42.75  ? 123 ILE B CA  1 
ATOM 4830 C C   . ILE C 3 133 ? 135.632 126.062 160.032 1.00 48.48  ? 123 ILE B C   1 
ATOM 4831 O O   . ILE C 3 133 ? 136.804 126.320 160.324 1.00 57.81  ? 123 ILE B O   1 
ATOM 4832 C CB  . ILE C 3 133 ? 134.866 124.523 161.873 1.00 37.79  ? 123 ILE B CB  1 
ATOM 4833 C CG1 . ILE C 3 133 ? 134.052 123.265 162.162 1.00 40.99  ? 123 ILE B CG1 1 
ATOM 4834 C CG2 . ILE C 3 133 ? 134.198 125.742 162.478 1.00 46.10  ? 123 ILE B CG2 1 
ATOM 4835 C CD1 . ILE C 3 133 ? 133.837 123.013 163.625 1.00 54.75  ? 123 ILE B CD1 1 
ATOM 4836 N N   . TYR C 3 134 ? 134.819 126.931 159.439 1.00 48.15  ? 124 TYR B N   1 
ATOM 4837 C CA  . TYR C 3 134 ? 135.269 128.223 158.948 1.00 40.00  ? 124 TYR B CA  1 
ATOM 4838 C C   . TYR C 3 134 ? 134.667 129.344 159.782 1.00 45.56  ? 124 TYR B C   1 
ATOM 4839 O O   . TYR C 3 134 ? 133.516 129.259 160.218 1.00 52.82  ? 124 TYR B O   1 
ATOM 4840 C CB  . TYR C 3 134 ? 134.897 128.405 157.475 1.00 35.27  ? 124 TYR B CB  1 
ATOM 4841 C CG  . TYR C 3 134 ? 135.472 127.335 156.578 1.00 49.00  ? 124 TYR B CG  1 
ATOM 4842 C CD1 . TYR C 3 134 ? 134.844 126.105 156.436 1.00 52.08  ? 124 TYR B CD1 1 
ATOM 4843 C CD2 . TYR C 3 134 ? 136.653 127.548 155.884 1.00 51.22  ? 124 TYR B CD2 1 
ATOM 4844 C CE1 . TYR C 3 134 ? 135.371 125.124 155.622 1.00 47.96  ? 124 TYR B CE1 1 
ATOM 4845 C CE2 . TYR C 3 134 ? 137.185 126.575 155.066 1.00 56.31  ? 124 TYR B CE2 1 
ATOM 4846 C CZ  . TYR C 3 134 ? 136.542 125.365 154.940 1.00 56.39  ? 124 TYR B CZ  1 
ATOM 4847 O OH  . TYR C 3 134 ? 137.075 124.394 154.129 1.00 59.59  ? 124 TYR B OH  1 
ATOM 4848 N N   . ASN C 3 135 ? 135.457 130.390 160.004 1.00 50.62  ? 125 ASN B N   1 
ATOM 4849 C CA  . ASN C 3 135 ? 135.040 131.550 160.779 1.00 46.40  ? 125 ASN B CA  1 
ATOM 4850 C C   . ASN C 3 135 ? 134.758 132.700 159.822 1.00 56.68  ? 125 ASN B C   1 
ATOM 4851 O O   . ASN C 3 135 ? 135.626 133.078 159.029 1.00 65.99  ? 125 ASN B O   1 
ATOM 4852 C CB  . ASN C 3 135 ? 136.116 131.933 161.794 1.00 43.90  ? 125 ASN B CB  1 
ATOM 4853 C CG  . ASN C 3 135 ? 135.701 133.086 162.679 1.00 57.44  ? 125 ASN B CG  1 
ATOM 4854 O OD1 . ASN C 3 135 ? 134.521 133.425 162.766 1.00 60.59  ? 125 ASN B OD1 1 
ATOM 4855 N ND2 . ASN C 3 135 ? 136.670 133.690 163.355 1.00 60.13  ? 125 ASN B ND2 1 
ATOM 4856 N N   . LEU C 3 136 ? 133.548 133.252 159.897 1.00 43.21  ? 126 LEU B N   1 
ATOM 4857 C CA  . LEU C 3 136 ? 133.128 134.301 158.976 1.00 32.42  ? 126 LEU B CA  1 
ATOM 4858 C C   . LEU C 3 136 ? 133.413 135.700 159.506 1.00 42.13  ? 126 LEU B C   1 
ATOM 4859 O O   . LEU C 3 136 ? 133.792 136.587 158.734 1.00 51.24  ? 126 LEU B O   1 
ATOM 4860 C CB  . LEU C 3 136 ? 131.636 134.164 158.668 1.00 37.73  ? 126 LEU B CB  1 
ATOM 4861 C CG  . LEU C 3 136 ? 131.179 132.827 158.090 1.00 28.21  ? 126 LEU B CG  1 
ATOM 4862 C CD1 . LEU C 3 136 ? 129.674 132.806 157.936 1.00 38.51  ? 126 LEU B CD1 1 
ATOM 4863 C CD2 . LEU C 3 136 ? 131.852 132.588 156.760 1.00 31.81  ? 126 LEU B CD2 1 
ATOM 4864 N N   . LYS C 3 137 ? 133.236 135.921 160.808 1.00 48.75  ? 127 LYS B N   1 
ATOM 4865 C CA  . LYS C 3 137 ? 133.423 137.240 161.408 1.00 46.91  ? 127 LYS B CA  1 
ATOM 4866 C C   . LYS C 3 137 ? 134.830 137.314 161.992 1.00 50.18  ? 127 LYS B C   1 
ATOM 4867 O O   . LYS C 3 137 ? 135.062 137.063 163.174 1.00 57.22  ? 127 LYS B O   1 
ATOM 4868 C CB  . LYS C 3 137 ? 132.355 137.509 162.462 1.00 45.46  ? 127 LYS B CB  1 
ATOM 4869 C CG  . LYS C 3 137 ? 130.965 137.043 162.070 1.00 49.78  ? 127 LYS B CG  1 
ATOM 4870 C CD  . LYS C 3 137 ? 130.362 137.944 161.007 1.00 50.32  ? 127 LYS B CD  1 
ATOM 4871 C CE  . LYS C 3 137 ? 128.877 137.679 160.843 1.00 47.13  ? 127 LYS B CE  1 
ATOM 4872 N NZ  . LYS C 3 137 ? 128.152 137.833 162.133 1.00 45.58  ? 127 LYS B NZ  1 
ATOM 4873 N N   . THR C 3 138 ? 135.782 137.666 161.137 1.00 55.57  ? 128 THR B N   1 
ATOM 4874 C CA  . THR C 3 138 ? 137.171 137.833 161.531 1.00 56.89  ? 128 THR B CA  1 
ATOM 4875 C C   . THR C 3 138 ? 137.566 139.301 161.458 1.00 61.91  ? 128 THR B C   1 
ATOM 4876 O O   . THR C 3 138 ? 136.967 140.096 160.729 1.00 57.23  ? 128 THR B O   1 
ATOM 4877 C CB  . THR C 3 138 ? 138.102 137.002 160.642 1.00 56.76  ? 128 THR B CB  1 
ATOM 4878 O OG1 . THR C 3 138 ? 137.817 137.275 159.266 1.00 63.25  ? 128 THR B OG1 1 
ATOM 4879 C CG2 . THR C 3 138 ? 137.923 135.520 160.911 1.00 57.26  ? 128 THR B CG2 1 
ATOM 4880 N N   . ARG C 3 139 ? 138.590 139.655 162.235 1.00 68.41  ? 129 ARG B N   1 
ATOM 4881 C CA  . ARG C 3 139 ? 139.103 141.018 162.229 1.00 66.76  ? 129 ARG B CA  1 
ATOM 4882 C C   . ARG C 3 139 ? 139.945 141.314 160.994 1.00 71.37  ? 129 ARG B C   1 
ATOM 4883 O O   . ARG C 3 139 ? 140.073 142.482 160.612 1.00 73.56  ? 129 ARG B O   1 
ATOM 4884 C CB  . ARG C 3 139 ? 139.920 141.273 163.500 1.00 65.15  ? 129 ARG B CB  1 
ATOM 4885 C CG  . ARG C 3 139 ? 140.351 142.718 163.693 1.00 65.54  ? 129 ARG B CG  1 
ATOM 4886 C CD  . ARG C 3 139 ? 140.014 143.220 165.088 1.00 70.25  ? 129 ARG B CD  1 
ATOM 4887 N NE  . ARG C 3 139 ? 140.164 144.666 165.193 1.00 72.31  ? 129 ARG B NE  1 
ATOM 4888 C CZ  . ARG C 3 139 ? 139.195 145.540 164.955 1.00 69.81  ? 129 ARG B CZ  1 
ATOM 4889 N NH1 . ARG C 3 139 ? 137.983 145.148 164.600 1.00 69.19  ? 129 ARG B NH1 1 
ATOM 4890 N NH2 . ARG C 3 139 ? 139.449 146.840 165.077 1.00 68.48  ? 129 ARG B NH2 1 
ATOM 4891 N N   . GLU C 3 140 ? 140.502 140.286 160.354 1.00 63.58  ? 130 GLU B N   1 
ATOM 4892 C CA  . GLU C 3 140 ? 141.325 140.477 159.168 1.00 58.93  ? 130 GLU B CA  1 
ATOM 4893 C C   . GLU C 3 140 ? 140.510 140.621 157.890 1.00 63.84  ? 130 GLU B C   1 
ATOM 4894 O O   . GLU C 3 140 ? 141.087 140.927 156.842 1.00 64.57  ? 130 GLU B O   1 
ATOM 4895 C CB  . GLU C 3 140 ? 142.307 139.314 159.018 1.00 58.42  ? 130 GLU B CB  1 
ATOM 4896 C CG  . GLU C 3 140 ? 143.400 139.293 160.068 1.00 66.74  ? 130 GLU B CG  1 
ATOM 4897 C CD  . GLU C 3 140 ? 143.052 138.419 161.253 1.00 71.46  ? 130 GLU B CD  1 
ATOM 4898 O OE1 . GLU C 3 140 ? 142.016 137.725 161.195 1.00 71.01  ? 130 GLU B OE1 1 
ATOM 4899 O OE2 . GLU C 3 140 ? 143.811 138.431 162.245 1.00 69.38  ? 130 GLU B OE2 1 
ATOM 4900 N N   . GLY C 3 141 ? 139.198 140.406 157.945 1.00 64.92  ? 131 GLY B N   1 
ATOM 4901 C CA  . GLY C 3 141 ? 138.348 140.575 156.788 1.00 63.53  ? 131 GLY B CA  1 
ATOM 4902 C C   . GLY C 3 141 ? 138.227 139.367 155.885 1.00 69.71  ? 131 GLY B C   1 
ATOM 4903 O O   . GLY C 3 141 ? 137.444 139.410 154.927 1.00 72.35  ? 131 GLY B O   1 
ATOM 4904 N N   . ASN C 3 142 ? 138.968 138.298 156.150 1.00 68.39  ? 132 ASN B N   1 
ATOM 4905 C CA  . ASN C 3 142 ? 138.888 137.075 155.367 1.00 58.35  ? 132 ASN B CA  1 
ATOM 4906 C C   . ASN C 3 142 ? 138.312 135.948 156.216 1.00 63.51  ? 132 ASN B C   1 
ATOM 4907 O O   . ASN C 3 142 ? 138.136 136.074 157.430 1.00 66.96  ? 132 ASN B O   1 
ATOM 4908 C CB  . ASN C 3 142 ? 140.265 136.684 154.813 1.00 58.10  ? 132 ASN B CB  1 
ATOM 4909 C CG  . ASN C 3 142 ? 141.356 136.721 155.867 1.00 65.81  ? 132 ASN B CG  1 
ATOM 4910 O OD1 . ASN C 3 142 ? 141.105 136.495 157.050 1.00 67.65  ? 132 ASN B OD1 1 
ATOM 4911 N ND2 . ASN C 3 142 ? 142.580 137.000 155.437 1.00 66.62  ? 132 ASN B ND2 1 
ATOM 4912 N N   . VAL C 3 143 ? 138.019 134.834 155.555 1.00 58.76  ? 133 VAL B N   1 
ATOM 4913 C CA  . VAL C 3 143 ? 137.448 133.660 156.203 1.00 50.08  ? 133 VAL B CA  1 
ATOM 4914 C C   . VAL C 3 143 ? 138.568 132.650 156.412 1.00 46.28  ? 133 VAL B C   1 
ATOM 4915 O O   . VAL C 3 143 ? 139.226 132.232 155.452 1.00 50.11  ? 133 VAL B O   1 
ATOM 4916 C CB  . VAL C 3 143 ? 136.304 133.064 155.369 1.00 44.76  ? 133 VAL B CB  1 
ATOM 4917 C CG1 . VAL C 3 143 ? 136.118 131.590 155.687 1.00 54.32  ? 133 VAL B CG1 1 
ATOM 4918 C CG2 . VAL C 3 143 ? 135.024 133.838 155.607 1.00 44.38  ? 133 VAL B CG2 1 
ATOM 4919 N N   . ARG C 3 144 ? 138.792 132.263 157.664 1.00 47.95  ? 134 ARG B N   1 
ATOM 4920 C CA  . ARG C 3 144 ? 139.861 131.346 158.023 1.00 57.30  ? 134 ARG B CA  1 
ATOM 4921 C C   . ARG C 3 144 ? 139.282 130.071 158.617 1.00 63.53  ? 134 ARG B C   1 
ATOM 4922 O O   . ARG C 3 144 ? 138.229 130.088 159.260 1.00 72.31  ? 134 ARG B O   1 
ATOM 4923 C CB  . ARG C 3 144 ? 140.828 131.979 159.031 1.00 59.10  ? 134 ARG B CB  1 
ATOM 4924 C CG  . ARG C 3 144 ? 141.490 133.260 158.560 1.00 68.33  ? 134 ARG B CG  1 
ATOM 4925 C CD  . ARG C 3 144 ? 142.584 133.696 159.523 1.00 67.29  ? 134 ARG B CD  1 
ATOM 4926 N NE  . ARG C 3 144 ? 142.055 134.460 160.647 1.00 63.54  ? 134 ARG B NE  1 
ATOM 4927 C CZ  . ARG C 3 144 ? 141.738 133.939 161.825 1.00 62.27  ? 134 ARG B CZ  1 
ATOM 4928 N NH1 . ARG C 3 144 ? 141.889 132.649 162.074 1.00 59.87  ? 134 ARG B NH1 1 
ATOM 4929 N NH2 . ARG C 3 144 ? 141.259 134.734 162.778 1.00 63.13  ? 134 ARG B NH2 1 
ATOM 4930 N N   . VAL C 3 145 ? 139.985 128.962 158.397 1.00 56.46  ? 135 VAL B N   1 
ATOM 4931 C CA  . VAL C 3 145 ? 139.610 127.684 158.989 1.00 49.78  ? 135 VAL B CA  1 
ATOM 4932 C C   . VAL C 3 145 ? 139.969 127.717 160.466 1.00 54.14  ? 135 VAL B C   1 
ATOM 4933 O O   . VAL C 3 145 ? 141.142 127.581 160.832 1.00 62.81  ? 135 VAL B O   1 
ATOM 4934 C CB  . VAL C 3 145 ? 140.304 126.509 158.279 1.00 54.23  ? 135 VAL B CB  1 
ATOM 4935 C CG1 . VAL C 3 145 ? 139.712 125.188 158.738 1.00 52.18  ? 135 VAL B CG1 1 
ATOM 4936 C CG2 . VAL C 3 145 ? 140.198 126.658 156.774 1.00 54.84  ? 135 VAL B CG2 1 
ATOM 4937 N N   . SER C 3 146 ? 138.967 127.909 161.324 1.00 51.05  ? 136 SER B N   1 
ATOM 4938 C CA  . SER C 3 146 ? 139.230 127.986 162.757 1.00 56.10  ? 136 SER B CA  1 
ATOM 4939 C C   . SER C 3 146 ? 139.731 126.652 163.297 1.00 61.66  ? 136 SER B C   1 
ATOM 4940 O O   . SER C 3 146 ? 140.704 126.607 164.058 1.00 70.59  ? 136 SER B O   1 
ATOM 4941 C CB  . SER C 3 146 ? 137.972 128.431 163.501 1.00 57.96  ? 136 SER B CB  1 
ATOM 4942 O OG  . SER C 3 146 ? 136.974 127.428 163.458 1.00 63.91  ? 136 SER B OG  1 
ATOM 4943 N N   . ARG C 3 147 ? 139.086 125.554 162.906 1.00 62.15  ? 137 ARG B N   1 
ATOM 4944 C CA  . ARG C 3 147 ? 139.452 124.229 163.382 1.00 61.46  ? 137 ARG B CA  1 
ATOM 4945 C C   . ARG C 3 147 ? 139.268 123.219 162.259 1.00 65.68  ? 137 ARG B C   1 
ATOM 4946 O O   . ARG C 3 147 ? 138.519 123.447 161.306 1.00 73.85  ? 137 ARG B O   1 
ATOM 4947 C CB  . ARG C 3 147 ? 138.613 123.808 164.598 1.00 57.86  ? 137 ARG B CB  1 
ATOM 4948 C CG  . ARG C 3 147 ? 139.012 124.475 165.904 1.00 62.40  ? 137 ARG B CG  1 
ATOM 4949 C CD  . ARG C 3 147 ? 140.493 124.306 166.194 1.00 65.16  ? 137 ARG B CD  1 
ATOM 4950 N NE  . ARG C 3 147 ? 140.798 123.023 166.813 1.00 70.88  ? 137 ARG B NE  1 
ATOM 4951 C CZ  . ARG C 3 147 ? 141.269 122.882 168.044 1.00 70.52  ? 137 ARG B CZ  1 
ATOM 4952 N NH1 . ARG C 3 147 ? 141.489 123.927 168.823 1.00 70.35  ? 137 ARG B NH1 1 
ATOM 4953 N NH2 . ARG C 3 147 ? 141.530 121.661 168.503 1.00 67.24  ? 137 ARG B NH2 1 
ATOM 4954 N N   . GLU C 3 148 ? 139.971 122.095 162.381 1.00 61.59  ? 138 GLU B N   1 
ATOM 4955 C CA  . GLU C 3 148 ? 139.791 120.945 161.500 1.00 56.37  ? 138 GLU B CA  1 
ATOM 4956 C C   . GLU C 3 148 ? 139.668 119.710 162.381 1.00 60.44  ? 138 GLU B C   1 
ATOM 4957 O O   . GLU C 3 148 ? 140.646 119.292 163.009 1.00 68.30  ? 138 GLU B O   1 
ATOM 4958 C CB  . GLU C 3 148 ? 140.949 120.807 160.512 1.00 56.96  ? 138 GLU B CB  1 
ATOM 4959 C CG  . GLU C 3 148 ? 140.694 121.471 159.167 1.00 60.34  ? 138 GLU B CG  1 
ATOM 4960 C CD  . GLU C 3 148 ? 141.933 121.530 158.295 1.00 63.68  ? 138 GLU B CD  1 
ATOM 4961 O OE1 . GLU C 3 148 ? 142.245 120.519 157.632 1.00 61.95  ? 138 GLU B OE1 1 
ATOM 4962 O OE2 . GLU C 3 148 ? 142.596 122.588 158.271 1.00 66.48  ? 138 GLU B OE2 1 
ATOM 4963 N N   . LEU C 3 149 ? 138.472 119.130 162.429 1.00 56.97  ? 139 LEU B N   1 
ATOM 4964 C CA  . LEU C 3 149 ? 138.169 118.041 163.349 1.00 57.93  ? 139 LEU B CA  1 
ATOM 4965 C C   . LEU C 3 149 ? 138.422 116.704 162.663 1.00 61.03  ? 139 LEU B C   1 
ATOM 4966 O O   . LEU C 3 149 ? 137.845 116.425 161.607 1.00 65.65  ? 139 LEU B O   1 
ATOM 4967 C CB  . LEU C 3 149 ? 136.722 118.136 163.827 1.00 54.53  ? 139 LEU B CB  1 
ATOM 4968 C CG  . LEU C 3 149 ? 136.275 119.509 164.330 1.00 54.19  ? 139 LEU B CG  1 
ATOM 4969 C CD1 . LEU C 3 149 ? 134.770 119.544 164.514 1.00 57.51  ? 139 LEU B CD1 1 
ATOM 4970 C CD2 . LEU C 3 149 ? 136.981 119.864 165.624 1.00 60.27  ? 139 LEU B CD2 1 
ATOM 4971 N N   . ALA C 3 150 ? 139.266 115.875 163.273 1.00 62.41  ? 140 ALA B N   1 
ATOM 4972 C CA  . ALA C 3 150 ? 139.647 114.589 162.711 1.00 61.15  ? 140 ALA B CA  1 
ATOM 4973 C C   . ALA C 3 150 ? 139.388 113.485 163.727 1.00 63.02  ? 140 ALA B C   1 
ATOM 4974 O O   . ALA C 3 150 ? 139.322 113.724 164.935 1.00 65.63  ? 140 ALA B O   1 
ATOM 4975 C CB  . ALA C 3 150 ? 141.121 114.573 162.287 1.00 62.28  ? 140 ALA B CB  1 
ATOM 4976 N N   . GLY C 3 151 ? 139.248 112.263 163.218 1.00 74.47  ? 141 GLY B N   1 
ATOM 4977 C CA  . GLY C 3 151 ? 138.988 111.117 164.066 1.00 76.29  ? 141 GLY B CA  1 
ATOM 4978 C C   . GLY C 3 151 ? 138.022 110.121 163.458 1.00 77.51  ? 141 GLY B C   1 
ATOM 4979 O O   . GLY C 3 151 ? 137.738 109.077 164.052 1.00 78.14  ? 141 GLY B O   1 
ATOM 4980 N N   . HIS C 3 152 ? 137.510 110.432 162.272 1.00 72.52  ? 142 HIS B N   1 
ATOM 4981 C CA  . HIS C 3 152 ? 136.588 109.559 161.562 1.00 68.22  ? 142 HIS B CA  1 
ATOM 4982 C C   . HIS C 3 152 ? 137.337 108.772 160.494 1.00 70.42  ? 142 HIS B C   1 
ATOM 4983 O O   . HIS C 3 152 ? 138.250 109.296 159.849 1.00 72.05  ? 142 HIS B O   1 
ATOM 4984 C CB  . HIS C 3 152 ? 135.459 110.365 160.919 1.00 72.44  ? 142 HIS B CB  1 
ATOM 4985 C CG  . HIS C 3 152 ? 134.298 110.616 161.831 1.00 72.66  ? 142 HIS B CG  1 
ATOM 4986 N ND1 . HIS C 3 152 ? 133.520 109.600 162.342 1.00 69.83  ? 142 HIS B ND1 1 
ATOM 4987 C CD2 . HIS C 3 152 ? 133.774 111.768 162.310 1.00 69.22  ? 142 HIS B CD2 1 
ATOM 4988 C CE1 . HIS C 3 152 ? 132.571 110.115 163.102 1.00 69.25  ? 142 HIS B CE1 1 
ATOM 4989 N NE2 . HIS C 3 152 ? 132.703 111.429 163.100 1.00 67.65  ? 142 HIS B NE2 1 
ATOM 4990 N N   . THR C 3 153 ? 136.949 107.512 160.314 1.00 71.73  ? 143 THR B N   1 
ATOM 4991 C CA  . THR C 3 153 ? 137.570 106.635 159.332 1.00 72.51  ? 143 THR B CA  1 
ATOM 4992 C C   . THR C 3 153 ? 136.748 106.500 158.057 1.00 70.41  ? 143 THR B C   1 
ATOM 4993 O O   . THR C 3 153 ? 137.082 105.676 157.202 1.00 70.90  ? 143 THR B O   1 
ATOM 4994 C CB  . THR C 3 153 ? 137.813 105.250 159.936 1.00 71.82  ? 143 THR B CB  1 
ATOM 4995 O OG1 . THR C 3 153 ? 136.624 104.462 159.815 1.00 70.50  ? 143 THR B OG1 1 
ATOM 4996 C CG2 . THR C 3 153 ? 138.188 105.368 161.404 1.00 73.36  ? 143 THR B CG2 1 
ATOM 4997 N N   . GLY C 3 154 ? 135.682 107.287 157.911 1.00 64.85  ? 144 GLY B N   1 
ATOM 4998 C CA  . GLY C 3 154 ? 134.835 107.201 156.739 1.00 61.80  ? 144 GLY B CA  1 
ATOM 4999 C C   . GLY C 3 154 ? 134.321 108.567 156.341 1.00 62.46  ? 144 GLY B C   1 
ATOM 5000 O O   . GLY C 3 154 ? 134.441 109.543 157.085 1.00 61.74  ? 144 GLY B O   1 
ATOM 5001 N N   . TYR C 3 155 ? 133.737 108.620 155.146 1.00 60.88  ? 145 TYR B N   1 
ATOM 5002 C CA  . TYR C 3 155 ? 133.241 109.877 154.605 1.00 48.38  ? 145 TYR B CA  1 
ATOM 5003 C C   . TYR C 3 155 ? 132.202 110.489 155.536 1.00 57.57  ? 145 TYR B C   1 
ATOM 5004 O O   . TYR C 3 155 ? 131.415 109.787 156.174 1.00 72.12  ? 145 TYR B O   1 
ATOM 5005 C CB  . TYR C 3 155 ? 132.643 109.659 153.215 1.00 49.99  ? 145 TYR B CB  1 
ATOM 5006 C CG  . TYR C 3 155 ? 131.432 108.751 153.193 1.00 61.60  ? 145 TYR B CG  1 
ATOM 5007 C CD1 . TYR C 3 155 ? 131.571 107.377 153.050 1.00 61.09  ? 145 TYR B CD1 1 
ATOM 5008 C CD2 . TYR C 3 155 ? 130.148 109.269 153.302 1.00 63.85  ? 145 TYR B CD2 1 
ATOM 5009 C CE1 . TYR C 3 155 ? 130.468 106.547 153.027 1.00 60.90  ? 145 TYR B CE1 1 
ATOM 5010 C CE2 . TYR C 3 155 ? 129.041 108.448 153.280 1.00 56.66  ? 145 TYR B CE2 1 
ATOM 5011 C CZ  . TYR C 3 155 ? 129.206 107.089 153.142 1.00 62.27  ? 145 TYR B CZ  1 
ATOM 5012 O OH  . TYR C 3 155 ? 128.103 106.270 153.119 1.00 70.76  ? 145 TYR B OH  1 
ATOM 5013 N N   . LEU C 3 156 ? 132.209 111.814 155.610 1.00 47.09  ? 146 LEU B N   1 
ATOM 5014 C CA  . LEU C 3 156 ? 131.363 112.559 156.528 1.00 43.93  ? 146 LEU B CA  1 
ATOM 5015 C C   . LEU C 3 156 ? 130.067 112.976 155.842 1.00 48.11  ? 146 LEU B C   1 
ATOM 5016 O O   . LEU C 3 156 ? 130.022 113.170 154.626 1.00 55.78  ? 146 LEU B O   1 
ATOM 5017 C CB  . LEU C 3 156 ? 132.099 113.794 157.045 1.00 40.78  ? 146 LEU B CB  1 
ATOM 5018 C CG  . LEU C 3 156 ? 131.625 114.386 158.366 1.00 39.96  ? 146 LEU B CG  1 
ATOM 5019 C CD1 . LEU C 3 156 ? 132.053 113.507 159.518 1.00 46.54  ? 146 LEU B CD1 1 
ATOM 5020 C CD2 . LEU C 3 156 ? 132.187 115.771 158.526 1.00 47.50  ? 146 LEU B CD2 1 
ATOM 5021 N N   . SER C 3 157 ? 129.006 113.108 156.637 1.00 50.36  ? 147 SER B N   1 
ATOM 5022 C CA  . SER C 3 157 ? 127.706 113.497 156.111 1.00 50.90  ? 147 SER B CA  1 
ATOM 5023 C C   . SER C 3 157 ? 126.887 114.179 157.199 1.00 51.17  ? 147 SER B C   1 
ATOM 5024 O O   . SER C 3 157 ? 126.935 113.781 158.365 1.00 47.62  ? 147 SER B O   1 
ATOM 5025 C CB  . SER C 3 157 ? 126.946 112.286 155.560 1.00 37.50  ? 147 SER B CB  1 
ATOM 5026 O OG  . SER C 3 157 ? 127.107 111.158 156.400 1.00 37.92  ? 147 SER B OG  1 
ATOM 5027 N N   . CYS C 3 158 ? 126.140 115.211 156.801 1.00 46.16  ? 148 CYS B N   1 
ATOM 5028 C CA  . CYS C 3 158 ? 125.176 115.909 157.654 1.00 39.34  ? 148 CYS B CA  1 
ATOM 5029 C C   . CYS C 3 158 ? 125.829 116.440 158.935 1.00 48.99  ? 148 CYS B C   1 
ATOM 5030 O O   . CYS C 3 158 ? 125.526 116.019 160.051 1.00 58.84  ? 148 CYS B O   1 
ATOM 5031 C CB  . CYS C 3 158 ? 123.975 115.012 157.969 1.00 37.12  ? 148 CYS B CB  1 
ATOM 5032 S SG  . CYS C 3 158 ? 122.620 115.199 156.788 1.00 59.88  ? 148 CYS B SG  1 
ATOM 5033 N N   . CYS C 3 159 ? 126.749 117.380 158.736 1.00 41.42  ? 149 CYS B N   1 
ATOM 5034 C CA  . CYS C 3 159 ? 127.214 118.205 159.842 1.00 31.48  ? 149 CYS B CA  1 
ATOM 5035 C C   . CYS C 3 159 ? 126.065 119.056 160.363 1.00 44.44  ? 149 CYS B C   1 
ATOM 5036 O O   . CYS C 3 159 ? 125.244 119.556 159.589 1.00 59.70  ? 149 CYS B O   1 
ATOM 5037 C CB  . CYS C 3 159 ? 128.360 119.110 159.398 1.00 41.65  ? 149 CYS B CB  1 
ATOM 5038 S SG  . CYS C 3 159 ? 129.781 118.259 158.703 1.00 69.34  ? 149 CYS B SG  1 
ATOM 5039 N N   . ARG C 3 160 ? 125.999 119.219 161.681 1.00 34.89  ? 150 ARG B N   1 
ATOM 5040 C CA  . ARG C 3 160 ? 124.968 120.046 162.289 1.00 29.63  ? 150 ARG B CA  1 
ATOM 5041 C C   . ARG C 3 160 ? 125.543 120.776 163.492 1.00 36.83  ? 150 ARG B C   1 
ATOM 5042 O O   . ARG C 3 160 ? 126.256 120.184 164.305 1.00 47.04  ? 150 ARG B O   1 
ATOM 5043 C CB  . ARG C 3 160 ? 123.755 119.213 162.712 1.00 24.72  ? 150 ARG B CB  1 
ATOM 5044 C CG  . ARG C 3 160 ? 122.780 118.932 161.584 1.00 28.99  ? 150 ARG B CG  1 
ATOM 5045 C CD  . ARG C 3 160 ? 122.297 120.211 160.926 1.00 29.18  ? 150 ARG B CD  1 
ATOM 5046 N NE  . ARG C 3 160 ? 121.457 119.933 159.768 1.00 25.68  ? 150 ARG B NE  1 
ATOM 5047 C CZ  . ARG C 3 160 ? 121.890 119.916 158.514 1.00 34.93  ? 150 ARG B CZ  1 
ATOM 5048 N NH1 . ARG C 3 160 ? 123.154 120.167 158.216 1.00 39.81  ? 150 ARG B NH1 1 
ATOM 5049 N NH2 . ARG C 3 160 ? 121.034 119.638 157.536 1.00 40.10  ? 150 ARG B NH2 1 
ATOM 5050 N N   . PHE C 3 161 ? 125.225 122.062 163.599 1.00 36.89  ? 151 PHE B N   1 
ATOM 5051 C CA  . PHE C 3 161 ? 125.725 122.900 164.678 1.00 36.75  ? 151 PHE B CA  1 
ATOM 5052 C C   . PHE C 3 161 ? 124.734 122.912 165.833 1.00 38.67  ? 151 PHE B C   1 
ATOM 5053 O O   . PHE C 3 161 ? 123.565 123.265 165.652 1.00 51.97  ? 151 PHE B O   1 
ATOM 5054 C CB  . PHE C 3 161 ? 125.959 124.327 164.181 1.00 41.81  ? 151 PHE B CB  1 
ATOM 5055 C CG  . PHE C 3 161 ? 127.368 124.599 163.742 1.00 36.40  ? 151 PHE B CG  1 
ATOM 5056 C CD1 . PHE C 3 161 ? 128.351 124.901 164.664 1.00 38.67  ? 151 PHE B CD1 1 
ATOM 5057 C CD2 . PHE C 3 161 ? 127.705 124.560 162.403 1.00 40.33  ? 151 PHE B CD2 1 
ATOM 5058 C CE1 . PHE C 3 161 ? 129.643 125.157 164.259 1.00 41.15  ? 151 PHE B CE1 1 
ATOM 5059 C CE2 . PHE C 3 161 ? 128.994 124.815 161.995 1.00 34.96  ? 151 PHE B CE2 1 
ATOM 5060 C CZ  . PHE C 3 161 ? 129.964 125.112 162.923 1.00 37.60  ? 151 PHE B CZ  1 
ATOM 5061 N N   . LEU C 3 162 ? 125.204 122.525 167.019 1.00 49.36  ? 152 LEU B N   1 
ATOM 5062 C CA  . LEU C 3 162 ? 124.398 122.694 168.222 1.00 49.80  ? 152 LEU B CA  1 
ATOM 5063 C C   . LEU C 3 162 ? 124.500 124.118 168.751 1.00 56.34  ? 152 LEU B C   1 
ATOM 5064 O O   . LEU C 3 162 ? 123.489 124.727 169.117 1.00 49.82  ? 152 LEU B O   1 
ATOM 5065 C CB  . LEU C 3 162 ? 124.840 121.707 169.301 1.00 49.32  ? 152 LEU B CB  1 
ATOM 5066 C CG  . LEU C 3 162 ? 124.436 120.241 169.175 1.00 53.20  ? 152 LEU B CG  1 
ATOM 5067 C CD1 . LEU C 3 162 ? 125.212 119.414 170.174 1.00 55.37  ? 152 LEU B CD1 1 
ATOM 5068 C CD2 . LEU C 3 162 ? 122.954 120.080 169.405 1.00 57.42  ? 152 LEU B CD2 1 
ATOM 5069 N N   . ASP C 3 163 ? 125.714 124.652 168.797 1.00 71.46  ? 153 ASP B N   1 
ATOM 5070 C CA  . ASP C 3 163 ? 125.990 126.001 169.266 1.00 66.53  ? 153 ASP B CA  1 
ATOM 5071 C C   . ASP C 3 163 ? 127.227 126.476 168.505 1.00 65.01  ? 153 ASP B C   1 
ATOM 5072 O O   . ASP C 3 163 ? 127.620 125.865 167.506 1.00 68.02  ? 153 ASP B O   1 
ATOM 5073 C CB  . ASP C 3 163 ? 126.137 125.994 170.801 1.00 68.67  ? 153 ASP B CB  1 
ATOM 5074 C CG  . ASP C 3 163 ? 126.350 127.377 171.385 1.00 73.83  ? 153 ASP B CG  1 
ATOM 5075 O OD1 . ASP C 3 163 ? 125.597 128.302 171.015 1.00 73.69  ? 153 ASP B OD1 1 
ATOM 5076 O OD2 . ASP C 3 163 ? 127.269 127.538 172.214 1.00 73.78  ? 153 ASP B OD2 1 
ATOM 5077 N N   . ASP C 3 164 ? 127.850 127.559 168.964 1.00 67.61  ? 154 ASP B N   1 
ATOM 5078 C CA  . ASP C 3 164 ? 129.060 128.045 168.316 1.00 67.21  ? 154 ASP B CA  1 
ATOM 5079 C C   . ASP C 3 164 ? 130.297 127.237 168.684 1.00 66.91  ? 154 ASP B C   1 
ATOM 5080 O O   . ASP C 3 164 ? 131.357 127.459 168.088 1.00 73.60  ? 154 ASP B O   1 
ATOM 5081 C CB  . ASP C 3 164 ? 129.287 129.518 168.659 1.00 71.69  ? 154 ASP B CB  1 
ATOM 5082 C CG  . ASP C 3 164 ? 128.571 130.455 167.705 1.00 75.19  ? 154 ASP B CG  1 
ATOM 5083 O OD1 . ASP C 3 164 ? 127.645 129.997 167.002 1.00 72.50  ? 154 ASP B OD1 1 
ATOM 5084 O OD2 . ASP C 3 164 ? 128.932 131.649 167.657 1.00 74.98  ? 154 ASP B OD2 1 
ATOM 5085 N N   . ASN C 3 165 ? 130.196 126.313 169.643 1.00 75.27  ? 155 ASN B N   1 
ATOM 5086 C CA  . ASN C 3 165 ? 131.330 125.476 170.020 1.00 78.36  ? 155 ASN B CA  1 
ATOM 5087 C C   . ASN C 3 165 ? 130.910 124.028 170.246 1.00 80.37  ? 155 ASN B C   1 
ATOM 5088 O O   . ASN C 3 165 ? 131.534 123.314 171.039 1.00 82.91  ? 155 ASN B O   1 
ATOM 5089 C CB  . ASN C 3 165 ? 132.027 126.021 171.269 1.00 77.33  ? 155 ASN B CB  1 
ATOM 5090 C CG  . ASN C 3 165 ? 131.124 126.026 172.486 1.00 81.77  ? 155 ASN B CG  1 
ATOM 5091 O OD1 . ASN C 3 165 ? 130.017 126.562 172.449 1.00 79.62  ? 155 ASN B OD1 1 
ATOM 5092 N ND2 . ASN C 3 165 ? 131.596 125.431 173.575 1.00 77.86  ? 155 ASN B ND2 1 
ATOM 5093 N N   . GLN C 3 166 ? 129.861 123.576 169.561 1.00 64.27  ? 156 GLN B N   1 
ATOM 5094 C CA  . GLN C 3 166 ? 129.390 122.200 169.686 1.00 54.12  ? 156 GLN B CA  1 
ATOM 5095 C C   . GLN C 3 166 ? 128.755 121.790 168.368 1.00 55.62  ? 156 GLN B C   1 
ATOM 5096 O O   . GLN C 3 166 ? 127.816 122.443 167.906 1.00 64.57  ? 156 GLN B O   1 
ATOM 5097 C CB  . GLN C 3 166 ? 128.390 122.064 170.835 1.00 54.69  ? 156 GLN B CB  1 
ATOM 5098 C CG  . GLN C 3 166 ? 129.003 121.569 172.132 1.00 64.52  ? 156 GLN B CG  1 
ATOM 5099 C CD  . GLN C 3 166 ? 127.960 121.152 173.149 1.00 72.11  ? 156 GLN B CD  1 
ATOM 5100 O OE1 . GLN C 3 166 ? 126.798 121.551 173.063 1.00 65.04  ? 156 GLN B OE1 1 
ATOM 5101 N NE2 . GLN C 3 166 ? 128.370 120.344 174.119 1.00 70.38  ? 156 GLN B NE2 1 
ATOM 5102 N N   . ILE C 3 167 ? 129.261 120.715 167.769 1.00 46.00  ? 157 ILE B N   1 
ATOM 5103 C CA  . ILE C 3 167 ? 128.840 120.284 166.442 1.00 39.66  ? 157 ILE B CA  1 
ATOM 5104 C C   . ILE C 3 167 ? 128.687 118.768 166.437 1.00 47.12  ? 157 ILE B C   1 
ATOM 5105 O O   . ILE C 3 167 ? 129.490 118.051 167.043 1.00 57.65  ? 157 ILE B O   1 
ATOM 5106 C CB  . ILE C 3 167 ? 129.842 120.753 165.365 1.00 43.18  ? 157 ILE B CB  1 
ATOM 5107 C CG1 . ILE C 3 167 ? 129.470 120.206 163.987 1.00 48.20  ? 157 ILE B CG1 1 
ATOM 5108 C CG2 . ILE C 3 167 ? 131.258 120.356 165.739 1.00 55.75  ? 157 ILE B CG2 1 
ATOM 5109 C CD1 . ILE C 3 167 ? 130.206 120.875 162.853 1.00 46.70  ? 157 ILE B CD1 1 
ATOM 5110 N N   . VAL C 3 168 ? 127.648 118.283 165.760 1.00 42.79  ? 158 VAL B N   1 
ATOM 5111 C CA  . VAL C 3 168 ? 127.373 116.857 165.624 1.00 38.57  ? 158 VAL B CA  1 
ATOM 5112 C C   . VAL C 3 168 ? 127.664 116.444 164.189 1.00 47.50  ? 158 VAL B C   1 
ATOM 5113 O O   . VAL C 3 168 ? 127.294 117.149 163.244 1.00 61.53  ? 158 VAL B O   1 
ATOM 5114 C CB  . VAL C 3 168 ? 125.918 116.519 166.001 1.00 34.11  ? 158 VAL B CB  1 
ATOM 5115 C CG1 . VAL C 3 168 ? 125.733 115.018 166.103 1.00 44.13  ? 158 VAL B CG1 1 
ATOM 5116 C CG2 . VAL C 3 168 ? 125.539 117.194 167.301 1.00 43.97  ? 158 VAL B CG2 1 
ATOM 5117 N N   . THR C 3 169 ? 128.328 115.301 164.026 1.00 49.21  ? 159 THR B N   1 
ATOM 5118 C CA  . THR C 3 169 ? 128.712 114.807 162.712 1.00 48.72  ? 159 THR B CA  1 
ATOM 5119 C C   . THR C 3 169 ? 128.259 113.363 162.545 1.00 48.95  ? 159 THR B C   1 
ATOM 5120 O O   . THR C 3 169 ? 128.051 112.636 163.518 1.00 54.59  ? 159 THR B O   1 
ATOM 5121 C CB  . THR C 3 169 ? 130.229 114.900 162.491 1.00 49.88  ? 159 THR B CB  1 
ATOM 5122 O OG1 . THR C 3 169 ? 130.910 114.192 163.533 1.00 56.69  ? 159 THR B OG1 1 
ATOM 5123 C CG2 . THR C 3 169 ? 130.683 116.350 162.494 1.00 41.05  ? 159 THR B CG2 1 
ATOM 5124 N N   . SER C 3 170 ? 128.106 112.960 161.285 1.00 38.01  ? 160 SER B N   1 
ATOM 5125 C CA  . SER C 3 170 ? 127.764 111.593 160.920 1.00 39.05  ? 160 SER B CA  1 
ATOM 5126 C C   . SER C 3 170 ? 128.736 111.107 159.858 1.00 41.91  ? 160 SER B C   1 
ATOM 5127 O O   . SER C 3 170 ? 129.153 111.880 158.991 1.00 51.54  ? 160 SER B O   1 
ATOM 5128 C CB  . SER C 3 170 ? 126.331 111.494 160.401 1.00 48.44  ? 160 SER B CB  1 
ATOM 5129 O OG  . SER C 3 170 ? 126.105 110.252 159.767 1.00 55.32  ? 160 SER B OG  1 
ATOM 5130 N N   . SER C 3 171 ? 129.090 109.826 159.919 1.00 48.58  ? 161 SER B N   1 
ATOM 5131 C CA  . SER C 3 171 ? 130.125 109.282 159.054 1.00 54.13  ? 161 SER B CA  1 
ATOM 5132 C C   . SER C 3 171 ? 129.691 107.942 158.486 1.00 55.67  ? 161 SER B C   1 
ATOM 5133 O O   . SER C 3 171 ? 128.670 107.371 158.877 1.00 68.26  ? 161 SER B O   1 
ATOM 5134 C CB  . SER C 3 171 ? 131.451 109.120 159.802 1.00 60.91  ? 161 SER B CB  1 
ATOM 5135 O OG  . SER C 3 171 ? 132.104 110.364 159.945 1.00 64.76  ? 161 SER B OG  1 
ATOM 5136 N N   . GLY C 3 172 ? 130.493 107.444 157.548 1.00 48.23  ? 162 GLY B N   1 
ATOM 5137 C CA  . GLY C 3 172 ? 130.362 106.104 157.025 1.00 49.13  ? 162 GLY B CA  1 
ATOM 5138 C C   . GLY C 3 172 ? 130.980 105.036 157.890 1.00 56.43  ? 162 GLY B C   1 
ATOM 5139 O O   . GLY C 3 172 ? 130.965 103.858 157.526 1.00 61.85  ? 162 GLY B O   1 
ATOM 5140 N N   . ASP C 3 173 ? 131.533 105.424 159.039 1.00 60.28  ? 163 ASP B N   1 
ATOM 5141 C CA  . ASP C 3 173 ? 132.077 104.500 160.023 1.00 61.27  ? 163 ASP B CA  1 
ATOM 5142 C C   . ASP C 3 173 ? 130.999 103.884 160.906 1.00 61.15  ? 163 ASP B C   1 
ATOM 5143 O O   . ASP C 3 173 ? 131.319 103.350 161.975 1.00 65.93  ? 163 ASP B O   1 
ATOM 5144 C CB  . ASP C 3 173 ? 133.122 105.213 160.887 1.00 61.19  ? 163 ASP B CB  1 
ATOM 5145 C CG  . ASP C 3 173 ? 134.096 104.252 161.540 1.00 66.64  ? 163 ASP B CG  1 
ATOM 5146 O OD1 . ASP C 3 173 ? 134.041 103.043 161.231 1.00 65.66  ? 163 ASP B OD1 1 
ATOM 5147 O OD2 . ASP C 3 173 ? 134.918 104.706 162.364 1.00 68.26  ? 163 ASP B OD2 1 
ATOM 5148 N N   . THR C 3 174 ? 129.736 103.953 160.480 1.00 59.11  ? 164 THR B N   1 
ATOM 5149 C CA  . THR C 3 174 ? 128.604 103.412 161.235 1.00 59.75  ? 164 THR B CA  1 
ATOM 5150 C C   . THR C 3 174 ? 128.534 104.009 162.639 1.00 61.52  ? 164 THR B C   1 
ATOM 5151 O O   . THR C 3 174 ? 128.200 103.324 163.607 1.00 63.94  ? 164 THR B O   1 
ATOM 5152 C CB  . THR C 3 174 ? 128.649 101.882 161.300 1.00 65.43  ? 164 THR B CB  1 
ATOM 5153 O OG1 . THR C 3 174 ? 129.512 101.471 162.368 1.00 62.65  ? 164 THR B OG1 1 
ATOM 5154 C CG2 . THR C 3 174 ? 129.146 101.293 159.984 1.00 63.65  ? 164 THR B CG2 1 
ATOM 5155 N N   . THR C 3 175 ? 128.850 105.297 162.752 1.00 59.97  ? 165 THR B N   1 
ATOM 5156 C CA  . THR C 3 175 ? 128.810 105.974 164.039 1.00 62.21  ? 165 THR B CA  1 
ATOM 5157 C C   . THR C 3 175 ? 128.611 107.467 163.830 1.00 62.07  ? 165 THR B C   1 
ATOM 5158 O O   . THR C 3 175 ? 128.981 108.022 162.792 1.00 61.20  ? 165 THR B O   1 
ATOM 5159 C CB  . THR C 3 175 ? 130.088 105.727 164.851 1.00 57.58  ? 165 THR B CB  1 
ATOM 5160 O OG1 . THR C 3 175 ? 129.968 106.352 166.134 1.00 56.14  ? 165 THR B OG1 1 
ATOM 5161 C CG2 . THR C 3 175 ? 131.301 106.292 164.130 1.00 58.25  ? 165 THR B CG2 1 
ATOM 5162 N N   . CYS C 3 176 ? 128.016 108.107 164.831 1.00 53.37  ? 166 CYS B N   1 
ATOM 5163 C CA  . CYS C 3 176 ? 127.878 109.553 164.889 1.00 49.46  ? 166 CYS B CA  1 
ATOM 5164 C C   . CYS C 3 176 ? 128.662 110.077 166.085 1.00 60.86  ? 166 CYS B C   1 
ATOM 5165 O O   . CYS C 3 176 ? 128.814 109.386 167.096 1.00 65.51  ? 166 CYS B O   1 
ATOM 5166 C CB  . CYS C 3 176 ? 126.410 109.971 164.999 1.00 42.38  ? 166 CYS B CB  1 
ATOM 5167 S SG  . CYS C 3 176 ? 125.406 109.562 163.555 1.00 47.63  ? 166 CYS B SG  1 
ATOM 5168 N N   . ALA C 3 177 ? 129.169 111.299 165.962 1.00 53.67  ? 167 ALA B N   1 
ATOM 5169 C CA  . ALA C 3 177 ? 130.045 111.867 166.973 1.00 46.57  ? 167 ALA B CA  1 
ATOM 5170 C C   . ALA C 3 177 ? 129.601 113.274 167.333 1.00 50.01  ? 167 ALA B C   1 
ATOM 5171 O O   . ALA C 3 177 ? 129.100 114.022 166.490 1.00 58.24  ? 167 ALA B O   1 
ATOM 5172 C CB  . ALA C 3 177 ? 131.499 111.898 166.495 1.00 48.59  ? 167 ALA B CB  1 
ATOM 5173 N N   . LEU C 3 178 ? 129.795 113.626 168.600 1.00 59.48  ? 168 LEU B N   1 
ATOM 5174 C CA  . LEU C 3 178 ? 129.577 114.979 169.095 1.00 59.27  ? 168 LEU B CA  1 
ATOM 5175 C C   . LEU C 3 178 ? 130.932 115.574 169.449 1.00 61.66  ? 168 LEU B C   1 
ATOM 5176 O O   . LEU C 3 178 ? 131.685 114.988 170.234 1.00 65.17  ? 168 LEU B O   1 
ATOM 5177 C CB  . LEU C 3 178 ? 128.647 114.982 170.307 1.00 56.25  ? 168 LEU B CB  1 
ATOM 5178 C CG  . LEU C 3 178 ? 128.636 116.276 171.121 1.00 52.58  ? 168 LEU B CG  1 
ATOM 5179 C CD1 . LEU C 3 178 ? 128.157 117.428 170.264 1.00 53.29  ? 168 LEU B CD1 1 
ATOM 5180 C CD2 . LEU C 3 178 ? 127.764 116.132 172.356 1.00 58.96  ? 168 LEU B CD2 1 
ATOM 5181 N N   . TRP C 3 179 ? 131.237 116.731 168.876 1.00 62.39  ? 169 TRP B N   1 
ATOM 5182 C CA  . TRP C 3 179 ? 132.552 117.340 168.993 1.00 60.91  ? 169 TRP B CA  1 
ATOM 5183 C C   . TRP C 3 179 ? 132.512 118.542 169.926 1.00 67.36  ? 169 TRP B C   1 
ATOM 5184 O O   . TRP C 3 179 ? 131.451 119.010 170.346 1.00 67.82  ? 169 TRP B O   1 
ATOM 5185 C CB  . TRP C 3 179 ? 133.074 117.773 167.619 1.00 56.48  ? 169 TRP B CB  1 
ATOM 5186 C CG  . TRP C 3 179 ? 133.190 116.663 166.632 1.00 57.69  ? 169 TRP B CG  1 
ATOM 5187 C CD1 . TRP C 3 179 ? 132.191 116.141 165.869 1.00 62.70  ? 169 TRP B CD1 1 
ATOM 5188 C CD2 . TRP C 3 179 ? 134.377 115.945 166.286 1.00 56.78  ? 169 TRP B CD2 1 
ATOM 5189 N NE1 . TRP C 3 179 ? 132.679 115.136 165.073 1.00 66.04  ? 169 TRP B NE1 1 
ATOM 5190 C CE2 . TRP C 3 179 ? 134.021 114.996 165.310 1.00 63.02  ? 169 TRP B CE2 1 
ATOM 5191 C CE3 . TRP C 3 179 ? 135.707 116.010 166.710 1.00 62.21  ? 169 TRP B CE3 1 
ATOM 5192 C CZ2 . TRP C 3 179 ? 134.944 114.119 164.751 1.00 65.23  ? 169 TRP B CZ2 1 
ATOM 5193 C CZ3 . TRP C 3 179 ? 136.622 115.139 166.153 1.00 65.72  ? 169 TRP B CZ3 1 
ATOM 5194 C CH2 . TRP C 3 179 ? 136.237 114.206 165.185 1.00 65.34  ? 169 TRP B CH2 1 
ATOM 5195 N N   . ASP C 3 180 ? 133.706 119.032 170.249 1.00 81.80  ? 170 ASP B N   1 
ATOM 5196 C CA  . ASP C 3 180 ? 133.893 120.301 170.943 1.00 81.00  ? 170 ASP B CA  1 
ATOM 5197 C C   . ASP C 3 180 ? 134.885 121.111 170.122 1.00 77.08  ? 170 ASP B C   1 
ATOM 5198 O O   . ASP C 3 180 ? 136.068 120.765 170.059 1.00 75.67  ? 170 ASP B O   1 
ATOM 5199 C CB  . ASP C 3 180 ? 134.397 120.091 172.371 1.00 82.66  ? 170 ASP B CB  1 
ATOM 5200 C CG  . ASP C 3 180 ? 134.179 121.306 173.250 1.00 83.51  ? 170 ASP B CG  1 
ATOM 5201 O OD1 . ASP C 3 180 ? 134.780 122.363 172.964 1.00 83.40  ? 170 ASP B OD1 1 
ATOM 5202 O OD2 . ASP C 3 180 ? 133.407 121.204 174.226 1.00 84.07  ? 170 ASP B OD2 1 
ATOM 5203 N N   . ILE C 3 181 ? 134.403 122.183 169.490 1.00 74.80  ? 171 ILE B N   1 
ATOM 5204 C CA  . ILE C 3 181 ? 135.236 122.938 168.558 1.00 77.56  ? 171 ILE B CA  1 
ATOM 5205 C C   . ILE C 3 181 ? 136.412 123.586 169.274 1.00 80.09  ? 171 ILE B C   1 
ATOM 5206 O O   . ILE C 3 181 ? 137.506 123.699 168.708 1.00 78.78  ? 171 ILE B O   1 
ATOM 5207 C CB  . ILE C 3 181 ? 134.383 123.980 167.809 1.00 77.18  ? 171 ILE B CB  1 
ATOM 5208 C CG1 . ILE C 3 181 ? 133.172 123.306 167.165 1.00 72.23  ? 171 ILE B CG1 1 
ATOM 5209 C CG2 . ILE C 3 181 ? 135.208 124.693 166.753 1.00 76.61  ? 171 ILE B CG2 1 
ATOM 5210 C CD1 . ILE C 3 181 ? 132.133 124.276 166.662 1.00 70.21  ? 171 ILE B CD1 1 
ATOM 5211 N N   . GLU C 3 182 ? 136.215 124.021 170.520 1.00 84.78  ? 172 GLU B N   1 
ATOM 5212 C CA  . GLU C 3 182 ? 137.294 124.657 171.269 1.00 84.16  ? 172 GLU B CA  1 
ATOM 5213 C C   . GLU C 3 182 ? 138.471 123.704 171.451 1.00 82.13  ? 172 GLU B C   1 
ATOM 5214 O O   . GLU C 3 182 ? 139.585 123.973 170.988 1.00 81.45  ? 172 GLU B O   1 
ATOM 5215 C CB  . GLU C 3 182 ? 136.774 125.143 172.622 1.00 85.12  ? 172 GLU B CB  1 
ATOM 5216 N N   . THR C 3 183 ? 138.240 122.578 172.129 1.00 85.22  ? 173 THR B N   1 
ATOM 5217 C CA  . THR C 3 183 ? 139.313 121.611 172.336 1.00 88.63  ? 173 THR B CA  1 
ATOM 5218 C C   . THR C 3 183 ? 139.672 120.893 171.040 1.00 88.89  ? 173 THR B C   1 
ATOM 5219 O O   . THR C 3 183 ? 140.854 120.663 170.759 1.00 87.08  ? 173 THR B O   1 
ATOM 5220 C CB  . THR C 3 183 ? 138.914 120.602 173.412 1.00 88.73  ? 173 THR B CB  1 
ATOM 5221 O OG1 . THR C 3 183 ? 137.955 119.681 172.876 1.00 88.95  ? 173 THR B OG1 1 
ATOM 5222 C CG2 . THR C 3 183 ? 138.308 121.315 174.611 1.00 86.93  ? 173 THR B CG2 1 
ATOM 5223 N N   . GLY C 3 184 ? 138.672 120.536 170.240 1.00 90.22  ? 174 GLY B N   1 
ATOM 5224 C CA  . GLY C 3 184 ? 138.898 119.791 169.020 1.00 87.00  ? 174 GLY B CA  1 
ATOM 5225 C C   . GLY C 3 184 ? 138.836 118.289 169.164 1.00 85.71  ? 174 GLY B C   1 
ATOM 5226 O O   . GLY C 3 184 ? 139.155 117.579 168.203 1.00 84.57  ? 174 GLY B O   1 
ATOM 5227 N N   . GLN C 3 185 ? 138.434 117.782 170.324 1.00 85.74  ? 175 GLN B N   1 
ATOM 5228 C CA  . GLN C 3 185 ? 138.407 116.354 170.594 1.00 86.75  ? 175 GLN B CA  1 
ATOM 5229 C C   . GLN C 3 185 ? 136.984 115.816 170.508 1.00 85.45  ? 175 GLN B C   1 
ATOM 5230 O O   . GLN C 3 185 ? 136.009 116.542 170.715 1.00 87.40  ? 175 GLN B O   1 
ATOM 5231 C CB  . GLN C 3 185 ? 138.993 116.050 171.974 1.00 87.71  ? 175 GLN B CB  1 
ATOM 5232 C CG  . GLN C 3 185 ? 140.345 116.697 172.234 1.00 88.29  ? 175 GLN B CG  1 
ATOM 5233 C CD  . GLN C 3 185 ? 141.447 116.119 171.369 1.00 88.84  ? 175 GLN B CD  1 
ATOM 5234 O OE1 . GLN C 3 185 ? 141.359 114.982 170.907 1.00 88.81  ? 175 GLN B OE1 1 
ATOM 5235 N NE2 . GLN C 3 185 ? 142.495 116.903 171.144 1.00 85.58  ? 175 GLN B NE2 1 
ATOM 5236 N N   . GLN C 3 186 ? 136.880 114.526 170.201 1.00 77.34  ? 176 GLN B N   1 
ATOM 5237 C CA  . GLN C 3 186 ? 135.595 113.837 170.118 1.00 75.49  ? 176 GLN B CA  1 
ATOM 5238 C C   . GLN C 3 186 ? 135.042 113.667 171.526 1.00 75.09  ? 176 GLN B C   1 
ATOM 5239 O O   . GLN C 3 186 ? 135.441 112.760 172.259 1.00 79.63  ? 176 GLN B O   1 
ATOM 5240 C CB  . GLN C 3 186 ? 135.771 112.492 169.422 1.00 73.29  ? 176 GLN B CB  1 
ATOM 5241 C CG  . GLN C 3 186 ? 134.584 112.037 168.596 1.00 71.51  ? 176 GLN B CG  1 
ATOM 5242 C CD  . GLN C 3 186 ? 134.967 110.978 167.581 1.00 77.09  ? 176 GLN B CD  1 
ATOM 5243 O OE1 . GLN C 3 186 ? 136.076 110.988 167.047 1.00 74.12  ? 176 GLN B OE1 1 
ATOM 5244 N NE2 . GLN C 3 186 ? 134.056 110.049 167.320 1.00 78.64  ? 176 GLN B NE2 1 
ATOM 5245 N N   . THR C 3 187 ? 134.117 114.548 171.913 1.00 67.26  ? 177 THR B N   1 
ATOM 5246 C CA  . THR C 3 187 ? 133.589 114.521 173.275 1.00 68.32  ? 177 THR B CA  1 
ATOM 5247 C C   . THR C 3 187 ? 132.780 113.255 173.530 1.00 70.14  ? 177 THR B C   1 
ATOM 5248 O O   . THR C 3 187 ? 132.998 112.556 174.526 1.00 69.56  ? 177 THR B O   1 
ATOM 5249 C CB  . THR C 3 187 ? 132.738 115.765 173.533 1.00 69.04  ? 177 THR B CB  1 
ATOM 5250 O OG1 . THR C 3 187 ? 133.586 116.917 173.613 1.00 65.92  ? 177 THR B OG1 1 
ATOM 5251 C CG2 . THR C 3 187 ? 131.965 115.624 174.834 1.00 72.40  ? 177 THR B CG2 1 
ATOM 5252 N N   . THR C 3 188 ? 131.845 112.939 172.637 1.00 70.99  ? 178 THR B N   1 
ATOM 5253 C CA  . THR C 3 188 ? 131.006 111.761 172.779 1.00 68.33  ? 178 THR B CA  1 
ATOM 5254 C C   . THR C 3 188 ? 130.894 111.066 171.431 1.00 71.00  ? 178 THR B C   1 
ATOM 5255 O O   . THR C 3 188 ? 130.926 111.710 170.379 1.00 77.91  ? 178 THR B O   1 
ATOM 5256 C CB  . THR C 3 188 ? 129.609 112.120 173.304 1.00 67.34  ? 178 THR B CB  1 
ATOM 5257 O OG1 . THR C 3 188 ? 129.724 113.124 174.320 1.00 67.96  ? 178 THR B OG1 1 
ATOM 5258 C CG2 . THR C 3 188 ? 128.926 110.898 173.893 1.00 69.13  ? 178 THR B CG2 1 
ATOM 5259 N N   . THR C 3 189 ? 130.767 109.743 171.470 1.00 61.27  ? 179 THR B N   1 
ATOM 5260 C CA  . THR C 3 189 ? 130.619 108.934 170.269 1.00 60.86  ? 179 THR B CA  1 
ATOM 5261 C C   . THR C 3 189 ? 129.380 108.066 170.410 1.00 63.82  ? 179 THR B C   1 
ATOM 5262 O O   . THR C 3 189 ? 129.202 107.397 171.433 1.00 67.47  ? 179 THR B O   1 
ATOM 5263 C CB  . THR C 3 189 ? 131.854 108.061 170.029 1.00 66.05  ? 179 THR B CB  1 
ATOM 5264 O OG1 . THR C 3 189 ? 133.030 108.879 170.047 1.00 69.36  ? 179 THR B OG1 1 
ATOM 5265 C CG2 . THR C 3 189 ? 131.757 107.359 168.686 1.00 65.85  ? 179 THR B CG2 1 
ATOM 5266 N N   . PHE C 3 190 ? 128.530 108.077 169.388 1.00 64.34  ? 180 PHE B N   1 
ATOM 5267 C CA  . PHE C 3 190 ? 127.308 107.285 169.368 1.00 64.06  ? 180 PHE B CA  1 
ATOM 5268 C C   . PHE C 3 190 ? 127.498 106.116 168.411 1.00 69.54  ? 180 PHE B C   1 
ATOM 5269 O O   . PHE C 3 190 ? 127.812 106.319 167.233 1.00 69.22  ? 180 PHE B O   1 
ATOM 5270 C CB  . PHE C 3 190 ? 126.107 108.133 168.949 1.00 61.32  ? 180 PHE B CB  1 
ATOM 5271 C CG  . PHE C 3 190 ? 126.086 109.504 169.562 1.00 65.21  ? 180 PHE B CG  1 
ATOM 5272 C CD1 . PHE C 3 190 ? 125.532 109.711 170.811 1.00 71.76  ? 180 PHE B CD1 1 
ATOM 5273 C CD2 . PHE C 3 190 ? 126.605 110.590 168.879 1.00 66.15  ? 180 PHE B CD2 1 
ATOM 5274 C CE1 . PHE C 3 190 ? 125.506 110.973 171.373 1.00 68.59  ? 180 PHE B CE1 1 
ATOM 5275 C CE2 . PHE C 3 190 ? 126.582 111.853 169.437 1.00 66.08  ? 180 PHE B CE2 1 
ATOM 5276 C CZ  . PHE C 3 190 ? 126.032 112.044 170.685 1.00 66.21  ? 180 PHE B CZ  1 
ATOM 5277 N N   . THR C 3 191 ? 127.308 104.900 168.917 1.00 66.24  ? 181 THR B N   1 
ATOM 5278 C CA  . THR C 3 191 ? 127.469 103.689 168.127 1.00 64.30  ? 181 THR B CA  1 
ATOM 5279 C C   . THR C 3 191 ? 126.241 102.805 168.293 1.00 67.61  ? 181 THR B C   1 
ATOM 5280 O O   . THR C 3 191 ? 125.481 102.933 169.256 1.00 64.20  ? 181 THR B O   1 
ATOM 5281 C CB  . THR C 3 191 ? 128.727 102.908 168.530 1.00 63.46  ? 181 THR B CB  1 
ATOM 5282 O OG1 . THR C 3 191 ? 128.693 102.634 169.936 1.00 62.26  ? 181 THR B OG1 1 
ATOM 5283 C CG2 . THR C 3 191 ? 129.979 103.707 168.207 1.00 64.27  ? 181 THR B CG2 1 
ATOM 5284 N N   . GLY C 3 192 ? 126.063 101.895 167.341 1.00 66.85  ? 182 GLY B N   1 
ATOM 5285 C CA  . GLY C 3 192 ? 124.922 101.002 167.351 1.00 64.18  ? 182 GLY B CA  1 
ATOM 5286 C C   . GLY C 3 192 ? 124.407 100.691 165.962 1.00 63.51  ? 182 GLY B C   1 
ATOM 5287 O O   . GLY C 3 192 ? 123.703 99.697  165.761 1.00 67.39  ? 182 GLY B O   1 
ATOM 5288 N N   . HIS C 3 193 ? 124.750 101.535 164.995 1.00 54.76  ? 183 HIS B N   1 
ATOM 5289 C CA  . HIS C 3 193 ? 124.387 101.269 163.613 1.00 55.50  ? 183 HIS B CA  1 
ATOM 5290 C C   . HIS C 3 193 ? 125.234 100.138 163.045 1.00 50.73  ? 183 HIS B C   1 
ATOM 5291 O O   . HIS C 3 193 ? 126.362 99.895  163.481 1.00 62.18  ? 183 HIS B O   1 
ATOM 5292 C CB  . HIS C 3 193 ? 124.561 102.525 162.761 1.00 62.47  ? 183 HIS B CB  1 
ATOM 5293 C CG  . HIS C 3 193 ? 123.382 103.446 162.791 1.00 59.33  ? 183 HIS B CG  1 
ATOM 5294 N ND1 . HIS C 3 193 ? 122.097 103.016 162.543 1.00 49.73  ? 183 HIS B ND1 1 
ATOM 5295 C CD2 . HIS C 3 193 ? 123.294 104.776 163.032 1.00 50.47  ? 183 HIS B CD2 1 
ATOM 5296 C CE1 . HIS C 3 193 ? 121.269 104.040 162.629 1.00 47.35  ? 183 HIS B CE1 1 
ATOM 5297 N NE2 . HIS C 3 193 ? 121.969 105.119 162.928 1.00 45.57  ? 183 HIS B NE2 1 
ATOM 5298 N N   . THR C 3 194 ? 124.673 99.436  162.060 1.00 53.04  ? 184 THR B N   1 
ATOM 5299 C CA  . THR C 3 194 ? 125.389 98.381  161.352 1.00 60.86  ? 184 THR B CA  1 
ATOM 5300 C C   . THR C 3 194 ? 125.595 98.728  159.882 1.00 64.20  ? 184 THR B C   1 
ATOM 5301 O O   . THR C 3 194 ? 125.757 97.830  159.050 1.00 67.83  ? 184 THR B O   1 
ATOM 5302 C CB  . THR C 3 194 ? 124.657 97.043  161.486 1.00 62.55  ? 184 THR B CB  1 
ATOM 5303 O OG1 . THR C 3 194 ? 125.172 96.116  160.523 1.00 67.52  ? 184 THR B OG1 1 
ATOM 5304 C CG2 . THR C 3 194 ? 123.167 97.223  161.264 1.00 56.09  ? 184 THR B CG2 1 
ATOM 5305 N N   . GLY C 3 195 ? 125.594 100.015 159.549 1.00 57.55  ? 185 GLY B N   1 
ATOM 5306 C CA  . GLY C 3 195 ? 125.809 100.456 158.184 1.00 57.50  ? 185 GLY B CA  1 
ATOM 5307 C C   . GLY C 3 195 ? 126.185 101.918 158.171 1.00 54.54  ? 185 GLY B C   1 
ATOM 5308 O O   . GLY C 3 195 ? 126.152 102.601 159.197 1.00 56.52  ? 185 GLY B O   1 
ATOM 5309 N N   . ASP C 3 196 ? 126.552 102.394 156.984 1.00 55.85  ? 186 ASP B N   1 
ATOM 5310 C CA  . ASP C 3 196 ? 126.962 103.783 156.833 1.00 52.75  ? 186 ASP B CA  1 
ATOM 5311 C C   . ASP C 3 196 ? 125.819 104.716 157.208 1.00 58.53  ? 186 ASP B C   1 
ATOM 5312 O O   . ASP C 3 196 ? 124.691 104.559 156.731 1.00 67.67  ? 186 ASP B O   1 
ATOM 5313 C CB  . ASP C 3 196 ? 127.408 104.046 155.396 1.00 55.40  ? 186 ASP B CB  1 
ATOM 5314 C CG  . ASP C 3 196 ? 128.411 103.024 154.902 1.00 65.07  ? 186 ASP B CG  1 
ATOM 5315 O OD1 . ASP C 3 196 ? 129.052 102.363 155.745 1.00 67.19  ? 186 ASP B OD1 1 
ATOM 5316 O OD2 . ASP C 3 196 ? 128.558 102.882 153.670 1.00 66.08  ? 186 ASP B OD2 1 
ATOM 5317 N N   . VAL C 3 197 ? 126.115 105.692 158.058 1.00 46.48  ? 187 VAL B N   1 
ATOM 5318 C CA  . VAL C 3 197 ? 125.121 106.655 158.519 1.00 37.74  ? 187 VAL B CA  1 
ATOM 5319 C C   . VAL C 3 197 ? 125.123 107.834 157.555 1.00 42.83  ? 187 VAL B C   1 
ATOM 5320 O O   . VAL C 3 197 ? 126.137 108.523 157.408 1.00 60.73  ? 187 VAL B O   1 
ATOM 5321 C CB  . VAL C 3 197 ? 125.415 107.110 159.954 1.00 28.72  ? 187 VAL B CB  1 
ATOM 5322 C CG1 . VAL C 3 197 ? 124.218 107.831 160.534 1.00 38.22  ? 187 VAL B CG1 1 
ATOM 5323 C CG2 . VAL C 3 197 ? 125.792 105.919 160.812 1.00 40.25  ? 187 VAL B CG2 1 
ATOM 5324 N N   . MET C 3 198 ? 123.987 108.071 156.902 1.00 36.73  ? 188 MET B N   1 
ATOM 5325 C CA  . MET C 3 198 ? 123.934 109.013 155.792 1.00 35.08  ? 188 MET B CA  1 
ATOM 5326 C C   . MET C 3 198 ? 123.388 110.384 156.159 1.00 43.09  ? 188 MET B C   1 
ATOM 5327 O O   . MET C 3 198 ? 123.790 111.374 155.541 1.00 53.64  ? 188 MET B O   1 
ATOM 5328 C CB  . MET C 3 198 ? 123.093 108.436 154.649 1.00 36.17  ? 188 MET B CB  1 
ATOM 5329 C CG  . MET C 3 198 ? 123.462 107.017 154.273 1.00 45.58  ? 188 MET B CG  1 
ATOM 5330 S SD  . MET C 3 198 ? 125.006 106.959 153.352 1.00 57.73  ? 188 MET B SD  1 
ATOM 5331 C CE  . MET C 3 198 ? 124.666 108.153 152.062 1.00 41.86  ? 188 MET B CE  1 
ATOM 5332 N N   . SER C 3 199 ? 122.486 110.485 157.133 1.00 31.65  ? 189 SER B N   1 
ATOM 5333 C CA  . SER C 3 199 ? 121.898 111.784 157.423 1.00 27.20  ? 189 SER B CA  1 
ATOM 5334 C C   . SER C 3 199 ? 121.401 111.827 158.858 1.00 32.97  ? 189 SER B C   1 
ATOM 5335 O O   . SER C 3 199 ? 121.055 110.798 159.443 1.00 43.25  ? 189 SER B O   1 
ATOM 5336 C CB  . SER C 3 199 ? 120.751 112.101 156.461 1.00 32.72  ? 189 SER B CB  1 
ATOM 5337 O OG  . SER C 3 199 ? 121.212 112.863 155.359 1.00 39.46  ? 189 SER B OG  1 
ATOM 5338 N N   . LEU C 3 200 ? 121.366 113.039 159.410 1.00 46.02  ? 190 LEU B N   1 
ATOM 5339 C CA  . LEU C 3 200 ? 120.835 113.274 160.744 1.00 43.05  ? 190 LEU B CA  1 
ATOM 5340 C C   . LEU C 3 200 ? 120.168 114.640 160.771 1.00 40.80  ? 190 LEU B C   1 
ATOM 5341 O O   . LEU C 3 200 ? 120.442 115.504 159.934 1.00 43.12  ? 190 LEU B O   1 
ATOM 5342 C CB  . LEU C 3 200 ? 121.927 113.189 161.821 1.00 33.53  ? 190 LEU B CB  1 
ATOM 5343 C CG  . LEU C 3 200 ? 123.029 114.252 161.869 1.00 33.28  ? 190 LEU B CG  1 
ATOM 5344 C CD1 . LEU C 3 200 ? 122.656 115.418 162.768 1.00 37.48  ? 190 LEU B CD1 1 
ATOM 5345 C CD2 . LEU C 3 200 ? 124.318 113.632 162.351 1.00 44.26  ? 190 LEU B CD2 1 
ATOM 5346 N N   . SER C 3 201 ? 119.285 114.826 161.749 1.00 31.36  ? 191 SER B N   1 
ATOM 5347 C CA  . SER C 3 201 ? 118.640 116.110 161.976 1.00 25.21  ? 191 SER B CA  1 
ATOM 5348 C C   . SER C 3 201 ? 118.516 116.346 163.472 1.00 32.30  ? 191 SER B C   1 
ATOM 5349 O O   . SER C 3 201 ? 118.206 115.424 164.230 1.00 41.84  ? 191 SER B O   1 
ATOM 5350 C CB  . SER C 3 201 ? 117.260 116.174 161.318 1.00 37.41  ? 191 SER B CB  1 
ATOM 5351 O OG  . SER C 3 201 ? 116.959 117.497 160.909 1.00 41.07  ? 191 SER B OG  1 
ATOM 5352 N N   . LEU C 3 202 ? 118.757 117.584 163.888 1.00 41.14  ? 192 LEU B N   1 
ATOM 5353 C CA  . LEU C 3 202 ? 118.719 117.949 165.296 1.00 40.24  ? 192 LEU B CA  1 
ATOM 5354 C C   . LEU C 3 202 ? 117.319 118.403 165.684 1.00 45.13  ? 192 LEU B C   1 
ATOM 5355 O O   . LEU C 3 202 ? 116.672 119.155 164.951 1.00 55.63  ? 192 LEU B O   1 
ATOM 5356 C CB  . LEU C 3 202 ? 119.728 119.058 165.591 1.00 41.58  ? 192 LEU B CB  1 
ATOM 5357 C CG  . LEU C 3 202 ? 121.173 118.620 165.829 1.00 43.87  ? 192 LEU B CG  1 
ATOM 5358 C CD1 . LEU C 3 202 ? 122.082 119.830 165.887 1.00 45.76  ? 192 LEU B CD1 1 
ATOM 5359 C CD2 . LEU C 3 202 ? 121.286 117.806 167.102 1.00 46.89  ? 192 LEU B CD2 1 
ATOM 5360 N N   . ALA C 3 203 ? 116.858 117.942 166.842 1.00 45.26  ? 193 ALA B N   1 
ATOM 5361 C CA  . ALA C 3 203 ? 115.531 118.302 167.307 1.00 50.84  ? 193 ALA B CA  1 
ATOM 5362 C C   . ALA C 3 203 ? 115.468 119.792 167.638 1.00 55.22  ? 193 ALA B C   1 
ATOM 5363 O O   . ALA C 3 203 ? 116.473 120.391 168.028 1.00 62.34  ? 193 ALA B O   1 
ATOM 5364 C CB  . ALA C 3 203 ? 115.151 117.481 168.536 1.00 54.83  ? 193 ALA B CB  1 
ATOM 5365 N N   . PRO C 3 204 ? 114.300 120.417 167.472 1.00 63.09  ? 194 PRO B N   1 
ATOM 5366 C CA  . PRO C 3 204 ? 114.168 121.828 167.873 1.00 64.84  ? 194 PRO B CA  1 
ATOM 5367 C C   . PRO C 3 204 ? 114.456 122.060 169.344 1.00 66.79  ? 194 PRO B C   1 
ATOM 5368 O O   . PRO C 3 204 ? 114.976 123.122 169.706 1.00 63.12  ? 194 PRO B O   1 
ATOM 5369 C CB  . PRO C 3 204 ? 112.709 122.160 167.521 1.00 66.35  ? 194 PRO B CB  1 
ATOM 5370 C CG  . PRO C 3 204 ? 112.031 120.837 167.334 1.00 66.14  ? 194 PRO B CG  1 
ATOM 5371 C CD  . PRO C 3 204 ? 113.079 119.905 166.833 1.00 63.74  ? 194 PRO B CD  1 
ATOM 5372 N N   . ASP C 3 205 ? 114.130 121.094 170.207 1.00 75.59  ? 195 ASP B N   1 
ATOM 5373 C CA  . ASP C 3 205 ? 114.490 121.192 171.616 1.00 76.44  ? 195 ASP B CA  1 
ATOM 5374 C C   . ASP C 3 205 ? 116.001 121.147 171.817 1.00 76.11  ? 195 ASP B C   1 
ATOM 5375 O O   . ASP C 3 205 ? 116.490 121.597 172.860 1.00 73.91  ? 195 ASP B O   1 
ATOM 5376 C CB  . ASP C 3 205 ? 113.789 120.075 172.397 1.00 75.77  ? 195 ASP B CB  1 
ATOM 5377 C CG  . ASP C 3 205 ? 114.262 119.966 173.834 1.00 80.65  ? 195 ASP B CG  1 
ATOM 5378 O OD1 . ASP C 3 205 ? 115.320 119.350 174.073 1.00 79.37  ? 195 ASP B OD1 1 
ATOM 5379 O OD2 . ASP C 3 205 ? 113.571 120.498 174.728 1.00 83.87  ? 195 ASP B OD2 1 
ATOM 5380 N N   . THR C 3 206 ? 116.741 120.624 170.836 1.00 70.22  ? 196 THR B N   1 
ATOM 5381 C CA  . THR C 3 206 ? 118.207 120.631 170.831 1.00 66.19  ? 196 THR B CA  1 
ATOM 5382 C C   . THR C 3 206 ? 118.767 119.801 171.988 1.00 66.88  ? 196 THR B C   1 
ATOM 5383 O O   . THR C 3 206 ? 119.714 120.197 172.671 1.00 70.88  ? 196 THR B O   1 
ATOM 5384 C CB  . THR C 3 206 ? 118.749 122.065 170.850 1.00 69.39  ? 196 THR B CB  1 
ATOM 5385 O OG1 . THR C 3 206 ? 118.003 122.860 169.922 1.00 72.86  ? 196 THR B OG1 1 
ATOM 5386 C CG2 . THR C 3 206 ? 120.205 122.098 170.414 1.00 62.61  ? 196 THR B CG2 1 
ATOM 5387 N N   . ARG C 3 207 ? 118.157 118.639 172.222 1.00 62.03  ? 197 ARG B N   1 
ATOM 5388 C CA  . ARG C 3 207 ? 118.690 117.652 173.149 1.00 60.13  ? 197 ARG B CA  1 
ATOM 5389 C C   . ARG C 3 207 ? 118.625 116.232 172.613 1.00 60.77  ? 197 ARG B C   1 
ATOM 5390 O O   . ARG C 3 207 ? 119.154 115.324 173.262 1.00 61.43  ? 197 ARG B O   1 
ATOM 5391 C CB  . ARG C 3 207 ? 117.951 117.711 174.494 1.00 65.66  ? 197 ARG B CB  1 
ATOM 5392 N N   . LEU C 3 208 ? 117.992 116.011 171.463 1.00 56.43  ? 198 LEU B N   1 
ATOM 5393 C CA  . LEU C 3 208 ? 117.896 114.699 170.846 1.00 53.47  ? 198 LEU B CA  1 
ATOM 5394 C C   . LEU C 3 208 ? 118.139 114.859 169.353 1.00 52.53  ? 198 LEU B C   1 
ATOM 5395 O O   . LEU C 3 208 ? 117.944 115.937 168.789 1.00 59.78  ? 198 LEU B O   1 
ATOM 5396 C CB  . LEU C 3 208 ? 116.522 114.061 171.092 1.00 51.56  ? 198 LEU B CB  1 
ATOM 5397 C CG  . LEU C 3 208 ? 116.125 113.731 172.534 1.00 55.87  ? 198 LEU B CG  1 
ATOM 5398 C CD1 . LEU C 3 208 ? 114.622 113.525 172.632 1.00 52.24  ? 198 LEU B CD1 1 
ATOM 5399 C CD2 . LEU C 3 208 ? 116.865 112.516 173.060 1.00 54.02  ? 198 LEU B CD2 1 
ATOM 5400 N N   . PHE C 3 209 ? 118.576 113.779 168.710 1.00 42.30  ? 199 PHE B N   1 
ATOM 5401 C CA  . PHE C 3 209 ? 118.691 113.786 167.260 1.00 45.86  ? 199 PHE B CA  1 
ATOM 5402 C C   . PHE C 3 209 ? 118.582 112.364 166.734 1.00 50.26  ? 199 PHE B C   1 
ATOM 5403 O O   . PHE C 3 209 ? 118.892 111.398 167.435 1.00 60.85  ? 199 PHE B O   1 
ATOM 5404 C CB  . PHE C 3 209 ? 119.996 114.441 166.784 1.00 44.74  ? 199 PHE B CB  1 
ATOM 5405 C CG  . PHE C 3 209 ? 121.216 113.579 166.939 1.00 48.43  ? 199 PHE B CG  1 
ATOM 5406 C CD1 . PHE C 3 209 ? 121.767 113.348 168.185 1.00 52.58  ? 199 PHE B CD1 1 
ATOM 5407 C CD2 . PHE C 3 209 ? 121.823 113.016 165.831 1.00 47.87  ? 199 PHE B CD2 1 
ATOM 5408 C CE1 . PHE C 3 209 ? 122.898 112.568 168.323 1.00 52.62  ? 199 PHE B CE1 1 
ATOM 5409 C CE2 . PHE C 3 209 ? 122.949 112.231 165.964 1.00 51.19  ? 199 PHE B CE2 1 
ATOM 5410 C CZ  . PHE C 3 209 ? 123.486 112.006 167.212 1.00 50.84  ? 199 PHE B CZ  1 
ATOM 5411 N N   . VAL C 3 210 ? 118.137 112.252 165.485 1.00 42.14  ? 200 VAL B N   1 
ATOM 5412 C CA  . VAL C 3 210 ? 117.894 110.974 164.830 1.00 41.95  ? 200 VAL B CA  1 
ATOM 5413 C C   . VAL C 3 210 ? 118.821 110.864 163.630 1.00 46.45  ? 200 VAL B C   1 
ATOM 5414 O O   . VAL C 3 210 ? 119.051 111.848 162.921 1.00 56.63  ? 200 VAL B O   1 
ATOM 5415 C CB  . VAL C 3 210 ? 116.422 110.828 164.395 1.00 41.34  ? 200 VAL B CB  1 
ATOM 5416 C CG1 . VAL C 3 210 ? 115.541 110.565 165.594 1.00 41.75  ? 200 VAL B CG1 1 
ATOM 5417 C CG2 . VAL C 3 210 ? 115.962 112.076 163.673 1.00 37.96  ? 200 VAL B CG2 1 
ATOM 5418 N N   . SER C 3 211 ? 119.357 109.668 163.410 1.00 28.48  ? 201 SER B N   1 
ATOM 5419 C CA  . SER C 3 211 ? 120.288 109.413 162.322 1.00 21.40  ? 201 SER B CA  1 
ATOM 5420 C C   . SER C 3 211 ? 119.745 108.311 161.425 1.00 33.24  ? 201 SER B C   1 
ATOM 5421 O O   . SER C 3 211 ? 119.230 107.301 161.911 1.00 51.96  ? 201 SER B O   1 
ATOM 5422 C CB  . SER C 3 211 ? 121.662 109.015 162.860 1.00 30.18  ? 201 SER B CB  1 
ATOM 5423 O OG  . SER C 3 211 ? 121.596 107.783 163.555 1.00 40.14  ? 201 SER B OG  1 
ATOM 5424 N N   . GLY C 3 212 ? 119.861 108.510 160.115 1.00 30.79  ? 202 GLY B N   1 
ATOM 5425 C CA  . GLY C 3 212 ? 119.420 107.513 159.161 1.00 25.22  ? 202 GLY B CA  1 
ATOM 5426 C C   . GLY C 3 212 ? 120.576 106.795 158.501 1.00 28.55  ? 202 GLY B C   1 
ATOM 5427 O O   . GLY C 3 212 ? 121.358 107.408 157.770 1.00 42.68  ? 202 GLY B O   1 
ATOM 5428 N N   . ALA C 3 213 ? 120.689 105.495 158.741 1.00 28.34  ? 203 ALA B N   1 
ATOM 5429 C CA  . ALA C 3 213 ? 121.830 104.725 158.281 1.00 37.81  ? 203 ALA B CA  1 
ATOM 5430 C C   . ALA C 3 213 ? 121.473 103.923 157.035 1.00 45.55  ? 203 ALA B C   1 
ATOM 5431 O O   . ALA C 3 213 ? 120.367 104.009 156.497 1.00 67.34  ? 203 ALA B O   1 
ATOM 5432 C CB  . ALA C 3 213 ? 122.336 103.808 159.393 1.00 42.35  ? 203 ALA B CB  1 
ATOM 5433 N N   . CYS C 3 214 ? 122.435 103.133 156.572 1.00 47.01  ? 204 CYS B N   1 
ATOM 5434 C CA  . CYS C 3 214 ? 122.280 102.318 155.376 1.00 49.72  ? 204 CYS B CA  1 
ATOM 5435 C C   . CYS C 3 214 ? 121.685 100.948 155.665 1.00 58.48  ? 204 CYS B C   1 
ATOM 5436 O O   . CYS C 3 214 ? 121.523 100.151 154.735 1.00 60.71  ? 204 CYS B O   1 
ATOM 5437 C CB  . CYS C 3 214 ? 123.631 102.151 154.678 1.00 55.34  ? 204 CYS B CB  1 
ATOM 5438 S SG  . CYS C 3 214 ? 124.026 103.465 153.513 1.00 73.62  ? 204 CYS B SG  1 
ATOM 5439 N N   . ASP C 3 215 ? 121.363 100.651 156.923 1.00 56.87  ? 205 ASP B N   1 
ATOM 5440 C CA  . ASP C 3 215 ? 120.763 99.380  157.297 1.00 58.69  ? 205 ASP B CA  1 
ATOM 5441 C C   . ASP C 3 215 ? 119.242 99.439  157.329 1.00 57.07  ? 205 ASP B C   1 
ATOM 5442 O O   . ASP C 3 215 ? 118.613 98.584  157.965 1.00 59.31  ? 205 ASP B O   1 
ATOM 5443 C CB  . ASP C 3 215 ? 121.296 98.924  158.656 1.00 56.21  ? 205 ASP B CB  1 
ATOM 5444 C CG  . ASP C 3 215 ? 120.916 99.869  159.773 1.00 60.21  ? 205 ASP B CG  1 
ATOM 5445 O OD1 . ASP C 3 215 ? 120.680 101.060 159.487 1.00 61.67  ? 205 ASP B OD1 1 
ATOM 5446 O OD2 . ASP C 3 215 ? 120.846 99.423  160.937 1.00 56.45  ? 205 ASP B OD2 1 
ATOM 5447 N N   . ALA C 3 216 ? 118.643 100.429 156.663 1.00 48.25  ? 206 ALA B N   1 
ATOM 5448 C CA  . ALA C 3 216 ? 117.190 100.595 156.620 1.00 52.98  ? 206 ALA B CA  1 
ATOM 5449 C C   . ALA C 3 216 ? 116.602 100.754 158.020 1.00 58.16  ? 206 ALA B C   1 
ATOM 5450 O O   . ALA C 3 216 ? 115.574 100.160 158.353 1.00 65.06  ? 206 ALA B O   1 
ATOM 5451 C CB  . ALA C 3 216 ? 116.521 99.434  155.880 1.00 55.69  ? 206 ALA B CB  1 
ATOM 5452 N N   . SER C 3 217 ? 117.260 101.560 158.850 1.00 46.02  ? 207 SER B N   1 
ATOM 5453 C CA  . SER C 3 217 ? 116.789 101.809 160.204 1.00 45.35  ? 207 SER B CA  1 
ATOM 5454 C C   . SER C 3 217 ? 117.309 103.156 160.678 1.00 45.59  ? 207 SER B C   1 
ATOM 5455 O O   . SER C 3 217 ? 118.480 103.483 160.474 1.00 58.94  ? 207 SER B O   1 
ATOM 5456 C CB  . SER C 3 217 ? 117.237 100.707 161.169 1.00 44.92  ? 207 SER B CB  1 
ATOM 5457 O OG  . SER C 3 217 ? 118.504 101.004 161.727 1.00 45.44  ? 207 SER B OG  1 
ATOM 5458 N N   . ALA C 3 218 ? 116.430 103.930 161.308 1.00 44.00  ? 208 ALA B N   1 
ATOM 5459 C CA  . ALA C 3 218 ? 116.779 105.212 161.902 1.00 42.45  ? 208 ALA B CA  1 
ATOM 5460 C C   . ALA C 3 218 ? 116.503 105.142 163.395 1.00 43.47  ? 208 ALA B C   1 
ATOM 5461 O O   . ALA C 3 218 ? 115.423 104.708 163.807 1.00 57.20  ? 208 ALA B O   1 
ATOM 5462 C CB  . ALA C 3 218 ? 115.984 106.353 161.266 1.00 43.24  ? 208 ALA B CB  1 
ATOM 5463 N N   . LYS C 3 219 ? 117.472 105.563 164.201 1.00 40.90  ? 209 LYS B N   1 
ATOM 5464 C CA  . LYS C 3 219 ? 117.372 105.434 165.646 1.00 52.88  ? 209 LYS B CA  1 
ATOM 5465 C C   . LYS C 3 219 ? 117.610 106.778 166.316 1.00 54.11  ? 209 LYS B C   1 
ATOM 5466 O O   . LYS C 3 219 ? 118.480 107.547 165.899 1.00 56.16  ? 209 LYS B O   1 
ATOM 5467 C CB  . LYS C 3 219 ? 118.360 104.390 166.176 1.00 55.74  ? 209 LYS B CB  1 
ATOM 5468 C CG  . LYS C 3 219 ? 119.708 104.399 165.499 1.00 57.85  ? 209 LYS B CG  1 
ATOM 5469 C CD  . LYS C 3 219 ? 120.690 103.501 166.227 1.00 58.34  ? 209 LYS B CD  1 
ATOM 5470 C CE  . LYS C 3 219 ? 120.210 102.062 166.251 1.00 53.18  ? 209 LYS B CE  1 
ATOM 5471 N NZ  . LYS C 3 219 ? 120.101 101.497 164.881 1.00 55.19  ? 209 LYS B NZ  1 
ATOM 5472 N N   . LEU C 3 220 ? 116.825 107.050 167.355 1.00 62.30  ? 210 LEU B N   1 
ATOM 5473 C CA  . LEU C 3 220 ? 116.906 108.311 168.077 1.00 56.72  ? 210 LEU B CA  1 
ATOM 5474 C C   . LEU C 3 220 ? 118.035 108.270 169.099 1.00 56.07  ? 210 LEU B C   1 
ATOM 5475 O O   . LEU C 3 220 ? 118.212 107.278 169.812 1.00 66.65  ? 210 LEU B O   1 
ATOM 5476 C CB  . LEU C 3 220 ? 115.574 108.603 168.768 1.00 57.33  ? 210 LEU B CB  1 
ATOM 5477 C CG  . LEU C 3 220 ? 115.503 109.718 169.811 1.00 57.72  ? 210 LEU B CG  1 
ATOM 5478 C CD1 . LEU C 3 220 ? 115.339 111.070 169.145 1.00 63.44  ? 210 LEU B CD1 1 
ATOM 5479 C CD2 . LEU C 3 220 ? 114.364 109.461 170.781 1.00 57.05  ? 210 LEU B CD2 1 
ATOM 5480 N N   . TRP C 3 221 ? 118.798 109.357 169.168 1.00 53.86  ? 211 TRP B N   1 
ATOM 5481 C CA  . TRP C 3 221 ? 119.940 109.470 170.060 1.00 61.05  ? 211 TRP B CA  1 
ATOM 5482 C C   . TRP C 3 221 ? 119.702 110.569 171.085 1.00 59.01  ? 211 TRP B C   1 
ATOM 5483 O O   . TRP C 3 221 ? 118.862 111.454 170.898 1.00 66.11  ? 211 TRP B O   1 
ATOM 5484 C CB  . TRP C 3 221 ? 121.230 109.791 169.300 1.00 62.87  ? 211 TRP B CB  1 
ATOM 5485 C CG  . TRP C 3 221 ? 121.621 108.820 168.240 1.00 58.83  ? 211 TRP B CG  1 
ATOM 5486 C CD1 . TRP C 3 221 ? 121.426 108.951 166.899 1.00 56.46  ? 211 TRP B CD1 1 
ATOM 5487 C CD2 . TRP C 3 221 ? 122.323 107.587 168.424 1.00 57.62  ? 211 TRP B CD2 1 
ATOM 5488 N NE1 . TRP C 3 221 ? 121.942 107.866 166.236 1.00 56.87  ? 211 TRP B NE1 1 
ATOM 5489 C CE2 . TRP C 3 221 ? 122.499 107.014 167.152 1.00 57.85  ? 211 TRP B CE2 1 
ATOM 5490 C CE3 . TRP C 3 221 ? 122.808 106.905 169.543 1.00 60.08  ? 211 TRP B CE3 1 
ATOM 5491 C CZ2 . TRP C 3 221 ? 123.141 105.795 166.966 1.00 59.73  ? 211 TRP B CZ2 1 
ATOM 5492 C CZ3 . TRP C 3 221 ? 123.444 105.696 169.357 1.00 60.79  ? 211 TRP B CZ3 1 
ATOM 5493 C CH2 . TRP C 3 221 ? 123.603 105.152 168.079 1.00 59.78  ? 211 TRP B CH2 1 
ATOM 5494 N N   . ASP C 3 222 ? 120.468 110.510 172.170 1.00 75.20  ? 212 ASP B N   1 
ATOM 5495 C CA  . ASP C 3 222 ? 120.516 111.566 173.170 1.00 82.78  ? 212 ASP B CA  1 
ATOM 5496 C C   . ASP C 3 222 ? 121.910 112.177 173.165 1.00 85.68  ? 212 ASP B C   1 
ATOM 5497 O O   . ASP C 3 222 ? 122.906 111.456 173.282 1.00 90.46  ? 212 ASP B O   1 
ATOM 5498 C CB  . ASP C 3 222 ? 120.173 111.026 174.559 1.00 86.16  ? 212 ASP B CB  1 
ATOM 5499 C CG  . ASP C 3 222 ? 119.748 112.118 175.520 1.00 87.89  ? 212 ASP B CG  1 
ATOM 5500 O OD1 . ASP C 3 222 ? 120.553 113.043 175.765 1.00 83.74  ? 212 ASP B OD1 1 
ATOM 5501 O OD2 . ASP C 3 222 ? 118.612 112.052 176.033 1.00 88.33  ? 212 ASP B OD2 1 
ATOM 5502 N N   . VAL C 3 223 ? 121.981 113.502 173.028 1.00 82.94  ? 213 VAL B N   1 
ATOM 5503 C CA  . VAL C 3 223 ? 123.280 114.159 172.925 1.00 83.58  ? 213 VAL B CA  1 
ATOM 5504 C C   . VAL C 3 223 ? 123.972 114.227 174.281 1.00 86.41  ? 213 VAL B C   1 
ATOM 5505 O O   . VAL C 3 223 ? 125.206 114.278 174.353 1.00 85.59  ? 213 VAL B O   1 
ATOM 5506 C CB  . VAL C 3 223 ? 123.129 115.560 172.303 1.00 82.10  ? 213 VAL B CB  1 
ATOM 5507 C CG1 . VAL C 3 223 ? 122.573 115.458 170.893 1.00 81.10  ? 213 VAL B CG1 1 
ATOM 5508 C CG2 . VAL C 3 223 ? 122.241 116.437 173.167 1.00 83.17  ? 213 VAL B CG2 1 
ATOM 5509 N N   . ARG C 3 224 ? 123.205 114.229 175.373 1.00 109.40 ? 214 ARG B N   1 
ATOM 5510 C CA  . ARG C 3 224 ? 123.801 114.400 176.694 1.00 110.85 ? 214 ARG B CA  1 
ATOM 5511 C C   . ARG C 3 224 ? 124.379 113.097 177.231 1.00 111.52 ? 214 ARG B C   1 
ATOM 5512 O O   . ARG C 3 224 ? 125.490 113.086 177.774 1.00 111.76 ? 214 ARG B O   1 
ATOM 5513 C CB  . ARG C 3 224 ? 122.763 114.961 177.666 1.00 110.55 ? 214 ARG B CB  1 
ATOM 5514 C CG  . ARG C 3 224 ? 123.242 115.047 179.106 1.00 111.74 ? 214 ARG B CG  1 
ATOM 5515 C CD  . ARG C 3 224 ? 122.080 114.976 180.084 1.00 112.19 ? 214 ARG B CD  1 
ATOM 5516 N NE  . ARG C 3 224 ? 121.221 116.151 180.004 1.00 114.22 ? 214 ARG B NE  1 
ATOM 5517 C CZ  . ARG C 3 224 ? 119.995 116.148 179.499 1.00 114.49 ? 214 ARG B CZ  1 
ATOM 5518 N NH1 . ARG C 3 224 ? 119.447 115.042 179.023 1.00 114.96 ? 214 ARG B NH1 1 
ATOM 5519 N NH2 . ARG C 3 224 ? 119.301 117.282 179.474 1.00 112.14 ? 214 ARG B NH2 1 
ATOM 5520 N N   . GLU C 3 225 ? 123.648 111.991 177.089 1.00 119.90 ? 215 GLU B N   1 
ATOM 5521 C CA  . GLU C 3 225 ? 124.073 110.713 177.643 1.00 120.01 ? 215 GLU B CA  1 
ATOM 5522 C C   . GLU C 3 225 ? 124.750 109.803 176.629 1.00 120.70 ? 215 GLU B C   1 
ATOM 5523 O O   . GLU C 3 225 ? 125.442 108.862 177.033 1.00 122.39 ? 215 GLU B O   1 
ATOM 5524 C CB  . GLU C 3 225 ? 122.875 109.973 178.250 1.00 119.97 ? 215 GLU B CB  1 
ATOM 5525 C CG  . GLU C 3 225 ? 122.155 110.742 179.343 1.00 121.44 ? 215 GLU B CG  1 
ATOM 5526 C CD  . GLU C 3 225 ? 122.569 110.302 180.732 1.00 122.72 ? 215 GLU B CD  1 
ATOM 5527 O OE1 . GLU C 3 225 ? 123.382 109.360 180.840 1.00 121.92 ? 215 GLU B OE1 1 
ATOM 5528 O OE2 . GLU C 3 225 ? 122.080 110.895 181.716 1.00 123.01 ? 215 GLU B OE2 1 
ATOM 5529 N N   . GLY C 3 226 ? 124.578 110.056 175.336 1.00 112.64 ? 216 GLY B N   1 
ATOM 5530 C CA  . GLY C 3 226 ? 125.138 109.176 174.326 1.00 108.84 ? 216 GLY B CA  1 
ATOM 5531 C C   . GLY C 3 226 ? 124.516 107.797 174.304 1.00 111.30 ? 216 GLY B C   1 
ATOM 5532 O O   . GLY C 3 226 ? 125.237 106.798 174.183 1.00 110.58 ? 216 GLY B O   1 
ATOM 5533 N N   . MET C 3 227 ? 123.193 107.716 174.417 1.00 103.22 ? 217 MET B N   1 
ATOM 5534 C CA  . MET C 3 227 ? 122.478 106.451 174.449 1.00 102.58 ? 217 MET B CA  1 
ATOM 5535 C C   . MET C 3 227 ? 121.450 106.406 173.328 1.00 100.52 ? 217 MET B C   1 
ATOM 5536 O O   . MET C 3 227 ? 120.858 107.426 172.965 1.00 100.20 ? 217 MET B O   1 
ATOM 5537 C CB  . MET C 3 227 ? 121.775 106.242 175.795 1.00 103.49 ? 217 MET B CB  1 
ATOM 5538 C CG  . MET C 3 227 ? 121.064 107.479 176.316 1.00 101.96 ? 217 MET B CG  1 
ATOM 5539 S SD  . MET C 3 227 ? 119.685 107.087 177.409 1.00 109.80 ? 217 MET B SD  1 
ATOM 5540 C CE  . MET C 3 227 ? 120.347 105.683 178.301 1.00 103.59 ? 217 MET B CE  1 
ATOM 5541 N N   . CYS C 3 228 ? 121.241 105.210 172.784 1.00 83.90  ? 218 CYS B N   1 
ATOM 5542 C CA  . CYS C 3 228 ? 120.227 104.992 171.756 1.00 78.98  ? 218 CYS B CA  1 
ATOM 5543 C C   . CYS C 3 228 ? 118.890 104.764 172.447 1.00 80.87  ? 218 CYS B C   1 
ATOM 5544 O O   . CYS C 3 228 ? 118.570 103.647 172.859 1.00 86.29  ? 218 CYS B O   1 
ATOM 5545 C CB  . CYS C 3 228 ? 120.603 103.811 170.871 1.00 87.25  ? 218 CYS B CB  1 
ATOM 5546 S SG  . CYS C 3 228 ? 119.416 103.461 169.559 1.00 92.01  ? 218 CYS B SG  1 
ATOM 5547 N N   . ARG C 3 229 ? 118.105 105.834 172.584 1.00 74.72  ? 219 ARG B N   1 
ATOM 5548 C CA  . ARG C 3 229 ? 116.817 105.728 173.262 1.00 77.38  ? 219 ARG B CA  1 
ATOM 5549 C C   . ARG C 3 229 ? 115.851 104.831 172.496 1.00 80.27  ? 219 ARG B C   1 
ATOM 5550 O O   . ARG C 3 229 ? 115.145 104.014 173.097 1.00 81.35  ? 219 ARG B O   1 
ATOM 5551 C CB  . ARG C 3 229 ? 116.212 107.117 173.454 1.00 78.97  ? 219 ARG B CB  1 
ATOM 5552 C CG  . ARG C 3 229 ? 116.693 107.845 174.696 1.00 78.39  ? 219 ARG B CG  1 
ATOM 5553 C CD  . ARG C 3 229 ? 116.036 109.210 174.816 1.00 79.78  ? 219 ARG B CD  1 
ATOM 5554 N NE  . ARG C 3 229 ? 114.698 109.222 174.237 1.00 83.73  ? 219 ARG B NE  1 
ATOM 5555 C CZ  . ARG C 3 229 ? 113.576 109.163 174.940 1.00 82.20  ? 219 ARG B CZ  1 
ATOM 5556 N NH1 . ARG C 3 229 ? 113.591 109.086 176.261 1.00 79.40  ? 219 ARG B NH1 1 
ATOM 5557 N NH2 . ARG C 3 229 ? 112.409 109.179 174.302 1.00 81.47  ? 219 ARG B NH2 1 
ATOM 5558 N N   . GLN C 3 230 ? 115.805 104.970 171.173 1.00 72.56  ? 220 GLN B N   1 
ATOM 5559 C CA  . GLN C 3 230 ? 114.811 104.292 170.355 1.00 64.24  ? 220 GLN B CA  1 
ATOM 5560 C C   . GLN C 3 230 ? 115.440 103.889 169.032 1.00 60.70  ? 220 GLN B C   1 
ATOM 5561 O O   . GLN C 3 230 ? 116.479 104.418 168.633 1.00 68.02  ? 220 GLN B O   1 
ATOM 5562 C CB  . GLN C 3 230 ? 113.596 105.188 170.094 1.00 61.99  ? 220 GLN B CB  1 
ATOM 5563 C CG  . GLN C 3 230 ? 112.900 105.697 171.337 1.00 65.09  ? 220 GLN B CG  1 
ATOM 5564 C CD  . GLN C 3 230 ? 111.415 105.832 171.134 1.00 67.12  ? 220 GLN B CD  1 
ATOM 5565 O OE1 . GLN C 3 230 ? 110.945 105.909 170.001 1.00 64.33  ? 220 GLN B OE1 1 
ATOM 5566 N NE2 . GLN C 3 230 ? 110.662 105.856 172.227 1.00 71.79  ? 220 GLN B NE2 1 
ATOM 5567 N N   . THR C 3 231 ? 114.796 102.940 168.356 1.00 52.49  ? 221 THR B N   1 
ATOM 5568 C CA  . THR C 3 231 ? 115.157 102.580 166.993 1.00 54.23  ? 221 THR B CA  1 
ATOM 5569 C C   . THR C 3 231 ? 113.882 102.346 166.195 1.00 57.73  ? 221 THR B C   1 
ATOM 5570 O O   . THR C 3 231 ? 112.853 101.940 166.743 1.00 62.13  ? 221 THR B O   1 
ATOM 5571 C CB  . THR C 3 231 ? 116.068 101.341 166.944 1.00 58.35  ? 221 THR B CB  1 
ATOM 5572 O OG1 . THR C 3 231 ? 116.874 101.386 165.761 1.00 59.64  ? 221 THR B OG1 1 
ATOM 5573 C CG2 . THR C 3 231 ? 115.257 100.055 166.945 1.00 65.28  ? 221 THR B CG2 1 
ATOM 5574 N N   . PHE C 3 232 ? 113.950 102.632 164.898 1.00 54.68  ? 222 PHE B N   1 
ATOM 5575 C CA  . PHE C 3 232 ? 112.795 102.543 164.017 1.00 55.90  ? 222 PHE B CA  1 
ATOM 5576 C C   . PHE C 3 232 ? 113.156 101.752 162.770 1.00 57.85  ? 222 PHE B C   1 
ATOM 5577 O O   . PHE C 3 232 ? 114.230 101.942 162.193 1.00 64.66  ? 222 PHE B O   1 
ATOM 5578 C CB  . PHE C 3 232 ? 112.291 103.933 163.623 1.00 52.20  ? 222 PHE B CB  1 
ATOM 5579 C CG  . PHE C 3 232 ? 111.855 104.770 164.788 1.00 51.25  ? 222 PHE B CG  1 
ATOM 5580 C CD1 . PHE C 3 232 ? 110.595 104.618 165.333 1.00 52.65  ? 222 PHE B CD1 1 
ATOM 5581 C CD2 . PHE C 3 232 ? 112.712 105.702 165.345 1.00 46.60  ? 222 PHE B CD2 1 
ATOM 5582 C CE1 . PHE C 3 232 ? 110.196 105.386 166.405 1.00 52.36  ? 222 PHE B CE1 1 
ATOM 5583 C CE2 . PHE C 3 232 ? 112.317 106.472 166.415 1.00 47.60  ? 222 PHE B CE2 1 
ATOM 5584 C CZ  . PHE C 3 232 ? 111.058 106.313 166.946 1.00 56.72  ? 222 PHE B CZ  1 
ATOM 5585 N N   . THR C 3 233 ? 112.251 100.868 162.358 1.00 53.30  ? 223 THR B N   1 
ATOM 5586 C CA  . THR C 3 233 ? 112.441 100.028 161.186 1.00 51.38  ? 223 THR B CA  1 
ATOM 5587 C C   . THR C 3 233 ? 111.215 100.126 160.289 1.00 52.92  ? 223 THR B C   1 
ATOM 5588 O O   . THR C 3 233 ? 110.181 100.683 160.666 1.00 52.02  ? 223 THR B O   1 
ATOM 5589 C CB  . THR C 3 233 ? 112.693 98.565  161.575 1.00 55.28  ? 223 THR B CB  1 
ATOM 5590 O OG1 . THR C 3 233 ? 111.553 98.052  162.275 1.00 60.30  ? 223 THR B OG1 1 
ATOM 5591 C CG2 . THR C 3 233 ? 113.924 98.446  162.460 1.00 53.62  ? 223 THR B CG2 1 
ATOM 5592 N N   . GLY C 3 234 ? 111.340 99.568  159.089 1.00 57.91  ? 224 GLY B N   1 
ATOM 5593 C CA  . GLY C 3 234 ? 110.245 99.563  158.140 1.00 56.93  ? 224 GLY B CA  1 
ATOM 5594 C C   . GLY C 3 234 ? 110.675 99.829  156.713 1.00 58.83  ? 224 GLY B C   1 
ATOM 5595 O O   . GLY C 3 234 ? 110.043 99.345  155.770 1.00 62.28  ? 224 GLY B O   1 
ATOM 5596 N N   . HIS C 3 235 ? 111.746 100.596 156.539 1.00 49.37  ? 225 HIS B N   1 
ATOM 5597 C CA  . HIS C 3 235 ? 112.243 100.886 155.203 1.00 47.00  ? 225 HIS B CA  1 
ATOM 5598 C C   . HIS C 3 235 ? 112.868 99.642  154.581 1.00 50.11  ? 225 HIS B C   1 
ATOM 5599 O O   . HIS C 3 235 ? 113.433 98.791  155.271 1.00 56.16  ? 225 HIS B O   1 
ATOM 5600 C CB  . HIS C 3 235 ? 113.262 102.022 155.248 1.00 51.34  ? 225 HIS B CB  1 
ATOM 5601 C CG  . HIS C 3 235 ? 112.645 103.383 155.188 1.00 50.29  ? 225 HIS B CG  1 
ATOM 5602 N ND1 . HIS C 3 235 ? 112.084 103.897 154.039 1.00 46.29  ? 225 HIS B ND1 1 
ATOM 5603 C CD2 . HIS C 3 235 ? 112.489 104.332 156.140 1.00 52.13  ? 225 HIS B CD2 1 
ATOM 5604 C CE1 . HIS C 3 235 ? 111.614 105.107 154.285 1.00 49.25  ? 225 HIS B CE1 1 
ATOM 5605 N NE2 . HIS C 3 235 ? 111.848 105.395 155.553 1.00 55.00  ? 225 HIS B NE2 1 
ATOM 5606 N N   . GLU C 3 236 ? 112.750 99.538  153.259 1.00 62.53  ? 226 GLU B N   1 
ATOM 5607 C CA  . GLU C 3 236 ? 113.281 98.394  152.532 1.00 64.47  ? 226 GLU B CA  1 
ATOM 5608 C C   . GLU C 3 236 ? 114.683 98.621  151.985 1.00 64.56  ? 226 GLU B C   1 
ATOM 5609 O O   . GLU C 3 236 ? 115.279 97.679  151.451 1.00 66.05  ? 226 GLU B O   1 
ATOM 5610 C CB  . GLU C 3 236 ? 112.344 98.018  151.378 1.00 63.13  ? 226 GLU B CB  1 
ATOM 5611 C CG  . GLU C 3 236 ? 111.292 96.984  151.748 1.00 65.01  ? 226 GLU B CG  1 
ATOM 5612 C CD  . GLU C 3 236 ? 109.992 97.176  150.991 1.00 69.46  ? 226 GLU B CD  1 
ATOM 5613 O OE1 . GLU C 3 236 ? 110.037 97.665  149.843 1.00 67.65  ? 226 GLU B OE1 1 
ATOM 5614 O OE2 . GLU C 3 236 ? 108.926 96.836  151.546 1.00 71.58  ? 226 GLU B OE2 1 
ATOM 5615 N N   . SER C 3 237 ? 115.227 99.829  152.100 1.00 61.27  ? 227 SER B N   1 
ATOM 5616 C CA  . SER C 3 237 ? 116.550 100.120 151.565 1.00 58.97  ? 227 SER B CA  1 
ATOM 5617 C C   . SER C 3 237 ? 117.219 101.162 152.455 1.00 55.48  ? 227 SER B C   1 
ATOM 5618 O O   . SER C 3 237 ? 116.700 101.530 153.512 1.00 60.21  ? 227 SER B O   1 
ATOM 5619 C CB  . SER C 3 237 ? 116.456 100.581 150.106 1.00 63.37  ? 227 SER B CB  1 
ATOM 5620 O OG  . SER C 3 237 ? 117.716 100.490 149.465 1.00 66.41  ? 227 SER B OG  1 
ATOM 5621 N N   . ASP C 3 238 ? 118.377 101.646 152.013 1.00 56.46  ? 228 ASP B N   1 
ATOM 5622 C CA  . ASP C 3 238 ? 119.165 102.576 152.811 1.00 56.90  ? 228 ASP B CA  1 
ATOM 5623 C C   . ASP C 3 238 ? 118.471 103.927 152.913 1.00 50.57  ? 228 ASP B C   1 
ATOM 5624 O O   . ASP C 3 238 ? 118.055 104.503 151.904 1.00 59.64  ? 228 ASP B O   1 
ATOM 5625 C CB  . ASP C 3 238 ? 120.553 102.739 152.196 1.00 56.09  ? 228 ASP B CB  1 
ATOM 5626 C CG  . ASP C 3 238 ? 120.524 102.704 150.682 1.00 59.27  ? 228 ASP B CG  1 
ATOM 5627 O OD1 . ASP C 3 238 ? 119.416 102.646 150.111 1.00 64.84  ? 228 ASP B OD1 1 
ATOM 5628 O OD2 . ASP C 3 238 ? 121.607 102.721 150.062 1.00 55.03  ? 228 ASP B OD2 1 
ATOM 5629 N N   . ILE C 3 239 ? 118.361 104.439 154.135 1.00 30.19  ? 229 ILE B N   1 
ATOM 5630 C CA  . ILE C 3 239 ? 117.750 105.741 154.371 1.00 34.10  ? 229 ILE B CA  1 
ATOM 5631 C C   . ILE C 3 239 ? 118.719 106.828 153.927 1.00 35.30  ? 229 ILE B C   1 
ATOM 5632 O O   . ILE C 3 239 ? 119.909 106.791 154.260 1.00 26.85  ? 229 ILE B O   1 
ATOM 5633 C CB  . ILE C 3 239 ? 117.366 105.900 155.850 1.00 25.01  ? 229 ILE B CB  1 
ATOM 5634 C CG1 . ILE C 3 239 ? 116.279 104.893 156.222 1.00 19.60  ? 229 ILE B CG1 1 
ATOM 5635 C CG2 . ILE C 3 239 ? 116.898 107.314 156.133 1.00 28.84  ? 229 ILE B CG2 1 
ATOM 5636 C CD1 . ILE C 3 239 ? 115.709 105.095 157.603 1.00 32.08  ? 229 ILE B CD1 1 
ATOM 5637 N N   . ASN C 3 240 ? 118.212 107.801 153.168 1.00 43.64  ? 230 ASN B N   1 
ATOM 5638 C CA  . ASN C 3 240 ? 119.052 108.809 152.541 1.00 32.50  ? 230 ASN B CA  1 
ATOM 5639 C C   . ASN C 3 240 ? 118.933 110.194 153.160 1.00 39.02  ? 230 ASN B C   1 
ATOM 5640 O O   . ASN C 3 240 ? 119.863 110.992 153.016 1.00 46.38  ? 230 ASN B O   1 
ATOM 5641 C CB  . ASN C 3 240 ? 118.723 108.908 151.044 1.00 36.19  ? 230 ASN B CB  1 
ATOM 5642 C CG  . ASN C 3 240 ? 119.956 108.845 150.171 1.00 47.75  ? 230 ASN B CG  1 
ATOM 5643 O OD1 . ASN C 3 240 ? 121.028 109.310 150.553 1.00 60.39  ? 230 ASN B OD1 1 
ATOM 5644 N ND2 . ASN C 3 240 ? 119.809 108.263 148.987 1.00 42.75  ? 230 ASN B ND2 1 
ATOM 5645 N N   . ALA C 3 241 ? 117.826 110.503 153.831 1.00 32.29  ? 231 ALA B N   1 
ATOM 5646 C CA  . ALA C 3 241 ? 117.664 111.810 154.451 1.00 32.10  ? 231 ALA B CA  1 
ATOM 5647 C C   . ALA C 3 241 ? 116.621 111.720 155.553 1.00 34.08  ? 231 ALA B C   1 
ATOM 5648 O O   . ALA C 3 241 ? 115.782 110.817 155.567 1.00 46.90  ? 231 ALA B O   1 
ATOM 5649 C CB  . ALA C 3 241 ? 117.266 112.872 153.424 1.00 32.32  ? 231 ALA B CB  1 
ATOM 5650 N N   . ILE C 3 242 ? 116.681 112.684 156.473 1.00 17.58  ? 232 ILE B N   1 
ATOM 5651 C CA  . ILE C 3 242 ? 115.778 112.740 157.616 1.00 21.55  ? 232 ILE B CA  1 
ATOM 5652 C C   . ILE C 3 242 ? 115.533 114.199 157.972 1.00 34.60  ? 232 ILE B C   1 
ATOM 5653 O O   . ILE C 3 242 ? 116.434 115.036 157.885 1.00 44.53  ? 232 ILE B O   1 
ATOM 5654 C CB  . ILE C 3 242 ? 116.344 111.957 158.827 1.00 22.09  ? 232 ILE B CB  1 
ATOM 5655 C CG1 . ILE C 3 242 ? 116.042 110.467 158.698 1.00 25.96  ? 232 ILE B CG1 1 
ATOM 5656 C CG2 . ILE C 3 242 ? 115.803 112.487 160.139 1.00 29.86  ? 232 ILE B CG2 1 
ATOM 5657 C CD1 . ILE C 3 242 ? 116.670 109.636 159.776 1.00 31.97  ? 232 ILE B CD1 1 
ATOM 5658 N N   . CYS C 3 243 ? 114.296 114.504 158.368 1.00 31.83  ? 233 CYS B N   1 
ATOM 5659 C CA  . CYS C 3 243 ? 113.943 115.814 158.893 1.00 28.01  ? 233 CYS B CA  1 
ATOM 5660 C C   . CYS C 3 243 ? 112.943 115.649 160.028 1.00 29.94  ? 233 CYS B C   1 
ATOM 5661 O O   . CYS C 3 243 ? 112.056 114.795 159.961 1.00 35.60  ? 233 CYS B O   1 
ATOM 5662 C CB  . CYS C 3 243 ? 113.354 116.718 157.805 1.00 29.20  ? 233 CYS B CB  1 
ATOM 5663 S SG  . CYS C 3 243 ? 113.234 118.457 158.275 1.00 51.95  ? 233 CYS B SG  1 
ATOM 5664 N N   . PHE C 3 244 ? 113.093 116.467 161.066 1.00 34.64  ? 234 PHE B N   1 
ATOM 5665 C CA  . PHE C 3 244 ? 112.193 116.433 162.210 1.00 31.30  ? 234 PHE B CA  1 
ATOM 5666 C C   . PHE C 3 244 ? 110.890 117.166 161.912 1.00 39.43  ? 234 PHE B C   1 
ATOM 5667 O O   . PHE C 3 244 ? 110.838 118.078 161.083 1.00 53.03  ? 234 PHE B O   1 
ATOM 5668 C CB  . PHE C 3 244 ? 112.852 117.066 163.435 1.00 31.63  ? 234 PHE B CB  1 
ATOM 5669 C CG  . PHE C 3 244 ? 113.211 116.086 164.512 1.00 34.68  ? 234 PHE B CG  1 
ATOM 5670 C CD1 . PHE C 3 244 ? 112.245 115.607 165.378 1.00 40.04  ? 234 PHE B CD1 1 
ATOM 5671 C CD2 . PHE C 3 244 ? 114.516 115.661 164.676 1.00 34.54  ? 234 PHE B CD2 1 
ATOM 5672 C CE1 . PHE C 3 244 ? 112.569 114.712 166.376 1.00 38.47  ? 234 PHE B CE1 1 
ATOM 5673 C CE2 . PHE C 3 244 ? 114.845 114.767 165.675 1.00 40.47  ? 234 PHE B CE2 1 
ATOM 5674 C CZ  . PHE C 3 244 ? 113.870 114.292 166.524 1.00 38.75  ? 234 PHE B CZ  1 
ATOM 5675 N N   . PHE C 3 245 ? 109.829 116.751 162.600 1.00 50.80  ? 235 PHE B N   1 
ATOM 5676 C CA  . PHE C 3 245 ? 108.590 117.508 162.583 1.00 52.51  ? 235 PHE B CA  1 
ATOM 5677 C C   . PHE C 3 245 ? 108.778 118.795 163.389 1.00 61.70  ? 235 PHE B C   1 
ATOM 5678 O O   . PHE C 3 245 ? 109.577 118.831 164.328 1.00 63.26  ? 235 PHE B O   1 
ATOM 5679 C CB  . PHE C 3 245 ? 107.448 116.674 163.162 1.00 48.60  ? 235 PHE B CB  1 
ATOM 5680 C CG  . PHE C 3 245 ? 106.086 117.068 162.664 1.00 50.96  ? 235 PHE B CG  1 
ATOM 5681 C CD1 . PHE C 3 245 ? 105.694 116.764 161.373 1.00 59.42  ? 235 PHE B CD1 1 
ATOM 5682 C CD2 . PHE C 3 245 ? 105.193 117.726 163.486 1.00 54.41  ? 235 PHE B CD2 1 
ATOM 5683 C CE1 . PHE C 3 245 ? 104.443 117.121 160.912 1.00 57.86  ? 235 PHE B CE1 1 
ATOM 5684 C CE2 . PHE C 3 245 ? 103.942 118.084 163.033 1.00 56.52  ? 235 PHE B CE2 1 
ATOM 5685 C CZ  . PHE C 3 245 ? 103.566 117.781 161.744 1.00 54.05  ? 235 PHE B CZ  1 
ATOM 5686 N N   . PRO C 3 246 ? 108.066 119.870 163.031 1.00 66.57  ? 236 PRO B N   1 
ATOM 5687 C CA  . PRO C 3 246 ? 108.333 121.166 163.681 1.00 66.99  ? 236 PRO B CA  1 
ATOM 5688 C C   . PRO C 3 246 ? 108.231 121.158 165.199 1.00 63.04  ? 236 PRO B C   1 
ATOM 5689 O O   . PRO C 3 246 ? 109.019 121.848 165.858 1.00 60.60  ? 236 PRO B O   1 
ATOM 5690 C CB  . PRO C 3 246 ? 107.279 122.079 163.044 1.00 65.01  ? 236 PRO B CB  1 
ATOM 5691 C CG  . PRO C 3 246 ? 107.128 121.526 161.676 1.00 60.85  ? 236 PRO B CG  1 
ATOM 5692 C CD  . PRO C 3 246 ? 107.224 120.031 161.833 1.00 63.57  ? 236 PRO B CD  1 
ATOM 5693 N N   . ASN C 3 247 ? 107.301 120.406 165.783 1.00 63.05  ? 237 ASN B N   1 
ATOM 5694 C CA  . ASN C 3 247 ? 107.134 120.424 167.231 1.00 67.96  ? 237 ASN B CA  1 
ATOM 5695 C C   . ASN C 3 247 ? 108.036 119.420 167.936 1.00 66.16  ? 237 ASN B C   1 
ATOM 5696 O O   . ASN C 3 247 ? 107.902 119.230 169.149 1.00 67.96  ? 237 ASN B O   1 
ATOM 5697 C CB  . ASN C 3 247 ? 105.672 120.164 167.612 1.00 69.30  ? 237 ASN B CB  1 
ATOM 5698 C CG  . ASN C 3 247 ? 105.252 118.731 167.376 1.00 66.76  ? 237 ASN B CG  1 
ATOM 5699 O OD1 . ASN C 3 247 ? 105.556 118.146 166.344 1.00 70.48  ? 237 ASN B OD1 1 
ATOM 5700 N ND2 . ASN C 3 247 ? 104.536 118.160 168.337 1.00 63.77  ? 237 ASN B ND2 1 
ATOM 5701 N N   . GLY C 3 248 ? 108.946 118.779 167.210 1.00 55.24  ? 238 GLY B N   1 
ATOM 5702 C CA  . GLY C 3 248 ? 109.883 117.852 167.819 1.00 56.26  ? 238 GLY B CA  1 
ATOM 5703 C C   . GLY C 3 248 ? 109.251 116.603 168.393 1.00 62.00  ? 238 GLY B C   1 
ATOM 5704 O O   . GLY C 3 248 ? 109.619 116.179 169.496 1.00 64.06  ? 238 GLY B O   1 
ATOM 5705 N N   . ASN C 3 249 ? 108.302 116.002 167.674 1.00 62.04  ? 239 ASN B N   1 
ATOM 5706 C CA  . ASN C 3 249 ? 107.682 114.767 168.134 1.00 59.28  ? 239 ASN B CA  1 
ATOM 5707 C C   . ASN C 3 249 ? 107.510 113.751 167.012 1.00 55.73  ? 239 ASN B C   1 
ATOM 5708 O O   . ASN C 3 249 ? 106.885 112.707 167.235 1.00 56.99  ? 239 ASN B O   1 
ATOM 5709 C CB  . ASN C 3 249 ? 106.329 115.056 168.788 1.00 56.14  ? 239 ASN B CB  1 
ATOM 5710 C CG  . ASN C 3 249 ? 106.446 115.296 170.278 1.00 64.90  ? 239 ASN B CG  1 
ATOM 5711 O OD1 . ASN C 3 249 ? 107.176 114.592 170.976 1.00 68.46  ? 239 ASN B OD1 1 
ATOM 5712 N ND2 . ASN C 3 249 ? 105.728 116.296 170.776 1.00 62.93  ? 239 ASN B ND2 1 
ATOM 5713 N N   . ALA C 3 250 ? 108.036 114.023 165.822 1.00 49.03  ? 240 ALA B N   1 
ATOM 5714 C CA  . ALA C 3 250 ? 107.985 113.086 164.710 1.00 43.86  ? 240 ALA B CA  1 
ATOM 5715 C C   . ALA C 3 250 ? 109.096 113.446 163.739 1.00 48.99  ? 240 ALA B C   1 
ATOM 5716 O O   . ALA C 3 250 ? 109.666 114.537 163.800 1.00 60.65  ? 240 ALA B O   1 
ATOM 5717 C CB  . ALA C 3 250 ? 106.622 113.108 164.011 1.00 47.20  ? 240 ALA B CB  1 
ATOM 5718 N N   . PHE C 3 251 ? 109.409 112.510 162.848 1.00 44.11  ? 241 PHE B N   1 
ATOM 5719 C CA  . PHE C 3 251 ? 110.403 112.770 161.819 1.00 40.23  ? 241 PHE B CA  1 
ATOM 5720 C C   . PHE C 3 251 ? 110.076 111.951 160.582 1.00 39.10  ? 241 PHE B C   1 
ATOM 5721 O O   . PHE C 3 251 ? 109.493 110.868 160.671 1.00 52.99  ? 241 PHE B O   1 
ATOM 5722 C CB  . PHE C 3 251 ? 111.823 112.469 162.315 1.00 40.17  ? 241 PHE B CB  1 
ATOM 5723 C CG  . PHE C 3 251 ? 112.054 111.032 162.681 1.00 34.72  ? 241 PHE B CG  1 
ATOM 5724 C CD1 . PHE C 3 251 ? 111.795 110.582 163.962 1.00 38.21  ? 241 PHE B CD1 1 
ATOM 5725 C CD2 . PHE C 3 251 ? 112.555 110.138 161.754 1.00 42.52  ? 241 PHE B CD2 1 
ATOM 5726 C CE1 . PHE C 3 251 ? 112.014 109.267 164.304 1.00 41.12  ? 241 PHE B CE1 1 
ATOM 5727 C CE2 . PHE C 3 251 ? 112.776 108.822 162.092 1.00 42.60  ? 241 PHE B CE2 1 
ATOM 5728 C CZ  . PHE C 3 251 ? 112.505 108.387 163.367 1.00 40.69  ? 241 PHE B CZ  1 
ATOM 5729 N N   . ALA C 3 252 ? 110.462 112.480 159.427 1.00 31.75  ? 242 ALA B N   1 
ATOM 5730 C CA  . ALA C 3 252 ? 110.197 111.854 158.141 1.00 33.97  ? 242 ALA B CA  1 
ATOM 5731 C C   . ALA C 3 252 ? 111.508 111.398 157.521 1.00 36.48  ? 242 ALA B C   1 
ATOM 5732 O O   . ALA C 3 252 ? 112.487 112.150 157.509 1.00 47.88  ? 242 ALA B O   1 
ATOM 5733 C CB  . ALA C 3 252 ? 109.473 112.817 157.199 1.00 39.42  ? 242 ALA B CB  1 
ATOM 5734 N N   . THR C 3 253 ? 111.522 110.172 157.008 1.00 30.20  ? 243 THR B N   1 
ATOM 5735 C CA  . THR C 3 253 ? 112.715 109.570 156.437 1.00 26.29  ? 243 THR B CA  1 
ATOM 5736 C C   . THR C 3 253 ? 112.515 109.329 154.948 1.00 34.68  ? 243 THR B C   1 
ATOM 5737 O O   . THR C 3 253 ? 111.396 109.097 154.485 1.00 53.22  ? 243 THR B O   1 
ATOM 5738 C CB  . THR C 3 253 ? 113.052 108.245 157.123 1.00 38.00  ? 243 THR B CB  1 
ATOM 5739 O OG1 . THR C 3 253 ? 112.045 107.278 156.807 1.00 37.55  ? 243 THR B OG1 1 
ATOM 5740 C CG2 . THR C 3 253 ? 113.104 108.423 158.625 1.00 38.84  ? 243 THR B CG2 1 
ATOM 5741 N N   . GLY C 3 254 ? 113.613 109.385 154.203 1.00 31.20  ? 244 GLY B N   1 
ATOM 5742 C CA  . GLY C 3 254 ? 113.576 109.103 152.782 1.00 35.73  ? 244 GLY B CA  1 
ATOM 5743 C C   . GLY C 3 254 ? 114.655 108.125 152.373 1.00 40.70  ? 244 GLY B C   1 
ATOM 5744 O O   . GLY C 3 254 ? 115.827 108.321 152.700 1.00 52.54  ? 244 GLY B O   1 
ATOM 5745 N N   . SER C 3 255 ? 114.280 107.071 151.659 1.00 36.63  ? 245 SER B N   1 
ATOM 5746 C CA  . SER C 3 255 ? 115.205 106.013 151.281 1.00 39.76  ? 245 SER B CA  1 
ATOM 5747 C C   . SER C 3 255 ? 115.228 105.855 149.765 1.00 40.79  ? 245 SER B C   1 
ATOM 5748 O O   . SER C 3 255 ? 114.504 106.532 149.032 1.00 53.34  ? 245 SER B O   1 
ATOM 5749 C CB  . SER C 3 255 ? 114.824 104.692 151.952 1.00 43.75  ? 245 SER B CB  1 
ATOM 5750 O OG  . SER C 3 255 ? 113.419 104.551 152.035 1.00 44.44  ? 245 SER B OG  1 
ATOM 5751 N N   . ASP C 3 256 ? 116.083 104.945 149.299 1.00 46.71  ? 246 ASP B N   1 
ATOM 5752 C CA  . ASP C 3 256 ? 116.122 104.581 147.890 1.00 55.56  ? 246 ASP B CA  1 
ATOM 5753 C C   . ASP C 3 256 ? 114.961 103.683 147.487 1.00 62.44  ? 246 ASP B C   1 
ATOM 5754 O O   . ASP C 3 256 ? 114.806 103.395 146.296 1.00 60.26  ? 246 ASP B O   1 
ATOM 5755 C CB  . ASP C 3 256 ? 117.447 103.894 147.559 1.00 52.24  ? 246 ASP B CB  1 
ATOM 5756 C CG  . ASP C 3 256 ? 118.646 104.745 147.917 1.00 62.72  ? 246 ASP B CG  1 
ATOM 5757 O OD1 . ASP C 3 256 ? 118.445 105.896 148.359 1.00 59.61  ? 246 ASP B OD1 1 
ATOM 5758 O OD2 . ASP C 3 256 ? 119.788 104.266 147.757 1.00 66.56  ? 246 ASP B OD2 1 
ATOM 5759 N N   . ASP C 3 257 ? 114.151 103.235 148.447 1.00 65.12  ? 247 ASP B N   1 
ATOM 5760 C CA  . ASP C 3 257 ? 112.942 102.468 148.173 1.00 59.22  ? 247 ASP B CA  1 
ATOM 5761 C C   . ASP C 3 257 ? 111.842 103.313 147.540 1.00 54.67  ? 247 ASP B C   1 
ATOM 5762 O O   . ASP C 3 257 ? 110.731 102.806 147.349 1.00 55.74  ? 247 ASP B O   1 
ATOM 5763 C CB  . ASP C 3 257 ? 112.439 101.830 149.471 1.00 58.94  ? 247 ASP B CB  1 
ATOM 5764 C CG  . ASP C 3 257 ? 111.407 100.745 149.232 1.00 67.20  ? 247 ASP B CG  1 
ATOM 5765 O OD1 . ASP C 3 257 ? 111.510 100.038 148.208 1.00 64.47  ? 247 ASP B OD1 1 
ATOM 5766 O OD2 . ASP C 3 257 ? 110.492 100.601 150.069 1.00 70.45  ? 247 ASP B OD2 1 
ATOM 5767 N N   . ALA C 3 258 ? 112.124 104.579 147.221 1.00 49.42  ? 248 ALA B N   1 
ATOM 5768 C CA  . ALA C 3 258 ? 111.158 105.492 146.612 1.00 54.09  ? 248 ALA B CA  1 
ATOM 5769 C C   . ALA C 3 258 ? 109.959 105.742 147.522 1.00 58.78  ? 248 ALA B C   1 
ATOM 5770 O O   . ALA C 3 258 ? 108.856 106.026 147.049 1.00 67.85  ? 248 ALA B O   1 
ATOM 5771 C CB  . ALA C 3 258 ? 110.694 104.985 145.243 1.00 61.38  ? 248 ALA B CB  1 
ATOM 5772 N N   . THR C 3 259 ? 110.164 105.644 148.833 1.00 48.07  ? 249 THR B N   1 
ATOM 5773 C CA  . THR C 3 259 ? 109.100 105.847 149.803 1.00 50.07  ? 249 THR B CA  1 
ATOM 5774 C C   . THR C 3 259 ? 109.569 106.792 150.898 1.00 54.65  ? 249 THR B C   1 
ATOM 5775 O O   . THR C 3 259 ? 110.751 106.833 151.245 1.00 65.48  ? 249 THR B O   1 
ATOM 5776 C CB  . THR C 3 259 ? 108.647 104.525 150.442 1.00 48.93  ? 249 THR B CB  1 
ATOM 5777 O OG1 . THR C 3 259 ? 109.766 103.881 151.062 1.00 49.98  ? 249 THR B OG1 1 
ATOM 5778 C CG2 . THR C 3 259 ? 108.055 103.597 149.398 1.00 53.82  ? 249 THR B CG2 1 
ATOM 5779 N N   . CYS C 3 260 ? 108.623 107.556 151.433 1.00 54.59  ? 250 CYS B N   1 
ATOM 5780 C CA  . CYS C 3 260 ? 108.834 108.366 152.621 1.00 41.54  ? 250 CYS B CA  1 
ATOM 5781 C C   . CYS C 3 260 ? 107.895 107.877 153.713 1.00 42.94  ? 250 CYS B C   1 
ATOM 5782 O O   . CYS C 3 260 ? 106.774 107.440 153.438 1.00 59.34  ? 250 CYS B O   1 
ATOM 5783 C CB  . CYS C 3 260 ? 108.590 109.854 152.345 1.00 46.04  ? 250 CYS B CB  1 
ATOM 5784 S SG  . CYS C 3 260 ? 109.956 110.704 151.526 1.00 59.08  ? 250 CYS B SG  1 
ATOM 5785 N N   . ARG C 3 261 ? 108.360 107.944 154.955 1.00 33.23  ? 251 ARG B N   1 
ATOM 5786 C CA  . ARG C 3 261 ? 107.592 107.460 156.089 1.00 41.60  ? 251 ARG B CA  1 
ATOM 5787 C C   . ARG C 3 261 ? 107.640 108.484 157.211 1.00 45.18  ? 251 ARG B C   1 
ATOM 5788 O O   . ARG C 3 261 ? 108.573 109.282 157.312 1.00 55.37  ? 251 ARG B O   1 
ATOM 5789 C CB  . ARG C 3 261 ? 108.115 106.106 156.582 1.00 49.76  ? 251 ARG B CB  1 
ATOM 5790 C CG  . ARG C 3 261 ? 107.858 104.968 155.614 1.00 53.50  ? 251 ARG B CG  1 
ATOM 5791 C CD  . ARG C 3 261 ? 108.661 103.734 155.969 1.00 47.62  ? 251 ARG B CD  1 
ATOM 5792 N NE  . ARG C 3 261 ? 108.639 102.754 154.890 1.00 48.58  ? 251 ARG B NE  1 
ATOM 5793 C CZ  . ARG C 3 261 ? 107.859 101.683 154.867 1.00 50.45  ? 251 ARG B CZ  1 
ATOM 5794 N NH1 . ARG C 3 261 ? 107.029 101.411 155.859 1.00 46.83  ? 251 ARG B NH1 1 
ATOM 5795 N NH2 . ARG C 3 261 ? 107.913 100.864 153.821 1.00 56.45  ? 251 ARG B NH2 1 
ATOM 5796 N N   . LEU C 3 262 ? 106.615 108.455 158.055 1.00 41.86  ? 252 LEU B N   1 
ATOM 5797 C CA  . LEU C 3 262 ? 106.498 109.366 159.188 1.00 49.32  ? 252 LEU B CA  1 
ATOM 5798 C C   . LEU C 3 262 ? 106.490 108.538 160.465 1.00 51.53  ? 252 LEU B C   1 
ATOM 5799 O O   . LEU C 3 262 ? 105.511 107.843 160.753 1.00 63.86  ? 252 LEU B O   1 
ATOM 5800 C CB  . LEU C 3 262 ? 105.237 110.222 159.071 1.00 50.66  ? 252 LEU B CB  1 
ATOM 5801 C CG  . LEU C 3 262 ? 105.012 111.306 160.125 1.00 49.82  ? 252 LEU B CG  1 
ATOM 5802 C CD1 . LEU C 3 262 ? 105.779 112.563 159.770 1.00 52.05  ? 252 LEU B CD1 1 
ATOM 5803 C CD2 . LEU C 3 262 ? 103.532 111.611 160.255 1.00 50.95  ? 252 LEU B CD2 1 
ATOM 5804 N N   . PHE C 3 263 ? 107.578 108.613 161.224 1.00 46.90  ? 253 PHE B N   1 
ATOM 5805 C CA  . PHE C 3 263 ? 107.704 107.910 162.491 1.00 50.99  ? 253 PHE B CA  1 
ATOM 5806 C C   . PHE C 3 263 ? 107.451 108.882 163.634 1.00 51.34  ? 253 PHE B C   1 
ATOM 5807 O O   . PHE C 3 263 ? 107.810 110.059 163.549 1.00 60.90  ? 253 PHE B O   1 
ATOM 5808 C CB  . PHE C 3 263 ? 109.090 107.282 162.642 1.00 49.79  ? 253 PHE B CB  1 
ATOM 5809 C CG  . PHE C 3 263 ? 109.468 106.360 161.521 1.00 50.61  ? 253 PHE B CG  1 
ATOM 5810 C CD1 . PHE C 3 263 ? 109.124 105.021 161.563 1.00 52.84  ? 253 PHE B CD1 1 
ATOM 5811 C CD2 . PHE C 3 263 ? 110.181 106.828 160.432 1.00 51.07  ? 253 PHE B CD2 1 
ATOM 5812 C CE1 . PHE C 3 263 ? 109.474 104.171 160.536 1.00 54.21  ? 253 PHE B CE1 1 
ATOM 5813 C CE2 . PHE C 3 263 ? 110.535 105.981 159.404 1.00 47.69  ? 253 PHE B CE2 1 
ATOM 5814 C CZ  . PHE C 3 263 ? 110.181 104.652 159.456 1.00 52.66  ? 253 PHE B CZ  1 
ATOM 5815 N N   . ASP C 3 264 ? 106.828 108.391 164.698 1.00 54.17  ? 254 ASP B N   1 
ATOM 5816 C CA  . ASP C 3 264 ? 106.486 109.217 165.845 1.00 55.39  ? 254 ASP B CA  1 
ATOM 5817 C C   . ASP C 3 264 ? 107.258 108.701 167.051 1.00 59.11  ? 254 ASP B C   1 
ATOM 5818 O O   . ASP C 3 264 ? 107.262 107.496 167.323 1.00 61.49  ? 254 ASP B O   1 
ATOM 5819 C CB  . ASP C 3 264 ? 104.967 109.209 166.077 1.00 58.59  ? 254 ASP B CB  1 
ATOM 5820 C CG  . ASP C 3 264 ? 104.543 109.820 167.416 1.00 71.87  ? 254 ASP B CG  1 
ATOM 5821 O OD1 . ASP C 3 264 ? 103.503 110.509 167.416 1.00 72.68  ? 254 ASP B OD1 1 
ATOM 5822 O OD2 . ASP C 3 264 ? 105.182 109.605 168.466 1.00 70.01  ? 254 ASP B OD2 1 
ATOM 5823 N N   . LEU C 3 265 ? 107.910 109.619 167.768 1.00 63.64  ? 255 LEU B N   1 
ATOM 5824 C CA  . LEU C 3 265 ? 108.756 109.229 168.891 1.00 61.13  ? 255 LEU B CA  1 
ATOM 5825 C C   . LEU C 3 265 ? 107.947 108.668 170.054 1.00 61.82  ? 255 LEU B C   1 
ATOM 5826 O O   . LEU C 3 265 ? 108.415 107.757 170.744 1.00 68.62  ? 255 LEU B O   1 
ATOM 5827 C CB  . LEU C 3 265 ? 109.591 110.423 169.353 1.00 62.87  ? 255 LEU B CB  1 
ATOM 5828 C CG  . LEU C 3 265 ? 110.560 111.000 168.319 1.00 62.74  ? 255 LEU B CG  1 
ATOM 5829 C CD1 . LEU C 3 265 ? 111.409 112.101 168.931 1.00 67.10  ? 255 LEU B CD1 1 
ATOM 5830 C CD2 . LEU C 3 265 ? 111.439 109.904 167.752 1.00 59.79  ? 255 LEU B CD2 1 
ATOM 5831 N N   . ARG C 3 266 ? 106.748 109.199 170.298 1.00 70.41  ? 256 ARG B N   1 
ATOM 5832 C CA  . ARG C 3 266 ? 105.953 108.729 171.428 1.00 77.00  ? 256 ARG B CA  1 
ATOM 5833 C C   . ARG C 3 266 ? 105.299 107.381 171.145 1.00 77.58  ? 256 ARG B C   1 
ATOM 5834 O O   . ARG C 3 266 ? 105.173 106.549 172.050 1.00 80.70  ? 256 ARG B O   1 
ATOM 5835 C CB  . ARG C 3 266 ? 104.889 109.764 171.790 1.00 76.79  ? 256 ARG B CB  1 
ATOM 5836 C CG  . ARG C 3 266 ? 105.368 110.840 172.746 1.00 77.81  ? 256 ARG B CG  1 
ATOM 5837 C CD  . ARG C 3 266 ? 104.198 111.458 173.489 1.00 74.66  ? 256 ARG B CD  1 
ATOM 5838 N NE  . ARG C 3 266 ? 103.222 112.025 172.567 1.00 75.94  ? 256 ARG B NE  1 
ATOM 5839 C CZ  . ARG C 3 266 ? 103.341 113.212 171.989 1.00 78.18  ? 256 ARG B CZ  1 
ATOM 5840 N NH1 . ARG C 3 266 ? 104.380 113.994 172.227 1.00 78.06  ? 256 ARG B NH1 1 
ATOM 5841 N NH2 . ARG C 3 266 ? 102.394 113.624 171.152 1.00 77.54  ? 256 ARG B NH2 1 
ATOM 5842 N N   . ALA C 3 267 ? 104.875 107.147 169.903 1.00 68.57  ? 257 ALA B N   1 
ATOM 5843 C CA  . ALA C 3 267 ? 104.198 105.906 169.552 1.00 70.82  ? 257 ALA B CA  1 
ATOM 5844 C C   . ALA C 3 267 ? 105.152 104.811 169.096 1.00 70.70  ? 257 ALA B C   1 
ATOM 5845 O O   . ALA C 3 267 ? 104.771 103.635 169.115 1.00 70.06  ? 257 ALA B O   1 
ATOM 5846 C CB  . ALA C 3 267 ? 103.161 106.163 168.456 1.00 73.69  ? 257 ALA B CB  1 
ATOM 5847 N N   . ASP C 3 268 ? 106.369 105.169 168.687 1.00 70.61  ? 258 ASP B N   1 
ATOM 5848 C CA  . ASP C 3 268 ? 107.416 104.241 168.267 1.00 67.13  ? 258 ASP B CA  1 
ATOM 5849 C C   . ASP C 3 268 ? 107.060 103.474 166.999 1.00 73.79  ? 258 ASP B C   1 
ATOM 5850 O O   . ASP C 3 268 ? 107.676 102.445 166.708 1.00 81.80  ? 258 ASP B O   1 
ATOM 5851 C CB  . ASP C 3 268 ? 107.768 103.243 169.376 1.00 71.86  ? 258 ASP B CB  1 
ATOM 5852 C CG  . ASP C 3 268 ? 107.954 103.908 170.717 1.00 73.91  ? 258 ASP B CG  1 
ATOM 5853 O OD1 . ASP C 3 268 ? 108.578 104.982 170.771 1.00 76.25  ? 258 ASP B OD1 1 
ATOM 5854 O OD2 . ASP C 3 268 ? 107.487 103.347 171.726 1.00 74.81  ? 258 ASP B OD2 1 
ATOM 5855 N N   . GLN C 3 269 ? 106.082 103.944 166.231 1.00 66.68  ? 259 GLN B N   1 
ATOM 5856 C CA  . GLN C 3 269 ? 105.668 103.274 165.009 1.00 60.65  ? 259 GLN B CA  1 
ATOM 5857 C C   . GLN C 3 269 ? 105.586 104.279 163.874 1.00 60.49  ? 259 GLN B C   1 
ATOM 5858 O O   . GLN C 3 269 ? 105.404 105.478 164.089 1.00 73.50  ? 259 GLN B O   1 
ATOM 5859 C CB  . GLN C 3 269 ? 104.306 102.583 165.162 1.00 65.82  ? 259 GLN B CB  1 
ATOM 5860 C CG  . GLN C 3 269 ? 104.045 101.995 166.527 1.00 67.28  ? 259 GLN B CG  1 
ATOM 5861 C CD  . GLN C 3 269 ? 102.594 101.622 166.731 1.00 72.51  ? 259 GLN B CD  1 
ATOM 5862 O OE1 . GLN C 3 269 ? 101.882 101.313 165.777 1.00 74.36  ? 259 GLN B OE1 1 
ATOM 5863 N NE2 . GLN C 3 269 ? 102.150 101.635 167.982 1.00 74.03  ? 259 GLN B NE2 1 
ATOM 5864 N N   . GLU C 3 270 ? 105.725 103.772 162.654 1.00 57.09  ? 260 GLU B N   1 
ATOM 5865 C CA  . GLU C 3 270 ? 105.415 104.581 161.487 1.00 61.98  ? 260 GLU B CA  1 
ATOM 5866 C C   . GLU C 3 270 ? 103.925 104.899 161.474 1.00 63.02  ? 260 GLU B C   1 
ATOM 5867 O O   . GLU C 3 270 ? 103.091 104.069 161.849 1.00 64.85  ? 260 GLU B O   1 
ATOM 5868 C CB  . GLU C 3 270 ? 105.836 103.856 160.206 1.00 58.42  ? 260 GLU B CB  1 
ATOM 5869 C CG  . GLU C 3 270 ? 104.763 102.991 159.568 1.00 61.02  ? 260 GLU B CG  1 
ATOM 5870 C CD  . GLU C 3 270 ? 105.126 102.555 158.165 1.00 69.76  ? 260 GLU B CD  1 
ATOM 5871 O OE1 . GLU C 3 270 ? 106.328 102.572 157.830 1.00 69.45  ? 260 GLU B OE1 1 
ATOM 5872 O OE2 . GLU C 3 270 ? 104.210 102.192 157.397 1.00 69.97  ? 260 GLU B OE2 1 
ATOM 5873 N N   . LEU C 3 271 ? 103.591 106.125 161.081 1.00 57.36  ? 261 LEU B N   1 
ATOM 5874 C CA  . LEU C 3 271 ? 102.201 106.561 161.067 1.00 57.57  ? 261 LEU B CA  1 
ATOM 5875 C C   . LEU C 3 271 ? 101.558 106.442 159.695 1.00 56.30  ? 261 LEU B C   1 
ATOM 5876 O O   . LEU C 3 271 ? 100.402 106.022 159.594 1.00 64.41  ? 261 LEU B O   1 
ATOM 5877 C CB  . LEU C 3 271 ? 102.092 108.006 161.564 1.00 55.47  ? 261 LEU B CB  1 
ATOM 5878 C CG  . LEU C 3 271 ? 102.581 108.241 162.994 1.00 54.65  ? 261 LEU B CG  1 
ATOM 5879 C CD1 . LEU C 3 271 ? 102.733 109.724 163.271 1.00 61.09  ? 261 LEU B CD1 1 
ATOM 5880 C CD2 . LEU C 3 271 ? 101.642 107.600 163.999 1.00 58.80  ? 261 LEU B CD2 1 
ATOM 5881 N N   . MET C 3 272 ? 102.280 106.796 158.637 1.00 49.56  ? 262 MET B N   1 
ATOM 5882 C CA  . MET C 3 272 ? 101.767 106.640 157.285 1.00 52.26  ? 262 MET B CA  1 
ATOM 5883 C C   . MET C 3 272 ? 102.938 106.632 156.317 1.00 53.83  ? 262 MET B C   1 
ATOM 5884 O O   . MET C 3 272 ? 104.054 107.030 156.661 1.00 56.44  ? 262 MET B O   1 
ATOM 5885 C CB  . MET C 3 272 ? 100.766 107.747 156.937 1.00 54.66  ? 262 MET B CB  1 
ATOM 5886 C CG  . MET C 3 272 ? 101.392 109.095 156.652 1.00 58.05  ? 262 MET B CG  1 
ATOM 5887 S SD  . MET C 3 272 ? 100.402 110.062 155.500 1.00 65.19  ? 262 MET B SD  1 
ATOM 5888 C CE  . MET C 3 272 ? 98.750  109.523 155.933 1.00 57.74  ? 262 MET B CE  1 
ATOM 5889 N N   . THR C 3 273 ? 102.669 106.165 155.102 1.00 53.01  ? 263 THR B N   1 
ATOM 5890 C CA  . THR C 3 273 ? 103.671 106.061 154.053 1.00 47.63  ? 263 THR B CA  1 
ATOM 5891 C C   . THR C 3 273 ? 103.311 106.999 152.910 1.00 51.56  ? 263 THR B C   1 
ATOM 5892 O O   . THR C 3 273 ? 102.135 107.279 152.662 1.00 62.10  ? 263 THR B O   1 
ATOM 5893 C CB  . THR C 3 273 ? 103.785 104.622 153.536 1.00 48.24  ? 263 THR B CB  1 
ATOM 5894 O OG1 . THR C 3 273 ? 103.725 103.713 154.641 1.00 51.08  ? 263 THR B OG1 1 
ATOM 5895 C CG2 . THR C 3 273 ? 105.098 104.420 152.801 1.00 49.57  ? 263 THR B CG2 1 
ATOM 5896 N N   . TYR C 3 274 ? 104.336 107.479 152.209 1.00 45.18  ? 264 TYR B N   1 
ATOM 5897 C CA  . TYR C 3 274 ? 104.148 108.474 151.162 1.00 51.79  ? 264 TYR B CA  1 
ATOM 5898 C C   . TYR C 3 274 ? 104.595 107.933 149.812 1.00 62.25  ? 264 TYR B C   1 
ATOM 5899 O O   . TYR C 3 274 ? 105.306 108.613 149.066 1.00 61.93  ? 264 TYR B O   1 
ATOM 5900 C CB  . TYR C 3 274 ? 104.912 109.752 151.507 1.00 53.45  ? 264 TYR B CB  1 
ATOM 5901 C CG  . TYR C 3 274 ? 104.477 110.383 152.808 1.00 48.99  ? 264 TYR B CG  1 
ATOM 5902 C CD1 . TYR C 3 274 ? 103.386 111.236 152.858 1.00 56.18  ? 264 TYR B CD1 1 
ATOM 5903 C CD2 . TYR C 3 274 ? 105.147 110.110 153.991 1.00 55.58  ? 264 TYR B CD2 1 
ATOM 5904 C CE1 . TYR C 3 274 ? 102.985 111.810 154.046 1.00 53.51  ? 264 TYR B CE1 1 
ATOM 5905 C CE2 . TYR C 3 274 ? 104.750 110.675 155.183 1.00 52.86  ? 264 TYR B CE2 1 
ATOM 5906 C CZ  . TYR C 3 274 ? 103.670 111.524 155.205 1.00 49.26  ? 264 TYR B CZ  1 
ATOM 5907 O OH  . TYR C 3 274 ? 103.275 112.089 156.394 1.00 58.95  ? 264 TYR B OH  1 
ATOM 5908 N N   . SER C 3 275 ? 104.188 106.707 149.495 1.00 72.57  ? 265 SER B N   1 
ATOM 5909 C CA  . SER C 3 275 ? 104.570 106.061 148.248 1.00 70.82  ? 265 SER B CA  1 
ATOM 5910 C C   . SER C 3 275 ? 103.531 106.315 147.166 1.00 73.25  ? 265 SER B C   1 
ATOM 5911 O O   . SER C 3 275 ? 102.326 106.328 147.433 1.00 71.50  ? 265 SER B O   1 
ATOM 5912 C CB  . SER C 3 275 ? 104.742 104.556 148.454 1.00 70.06  ? 265 SER B CB  1 
ATOM 5913 O OG  . SER C 3 275 ? 104.801 103.878 147.212 1.00 74.20  ? 265 SER B OG  1 
ATOM 5914 N N   . HIS C 3 276 ? 104.008 106.519 145.942 1.00 94.35  ? 266 HIS B N   1 
ATOM 5915 C CA  . HIS C 3 276 ? 103.160 106.663 144.769 1.00 97.53  ? 266 HIS B CA  1 
ATOM 5916 C C   . HIS C 3 276 ? 103.581 105.639 143.725 1.00 98.98  ? 266 HIS B C   1 
ATOM 5917 O O   . HIS C 3 276 ? 104.769 105.327 143.592 1.00 96.56  ? 266 HIS B O   1 
ATOM 5918 C CB  . HIS C 3 276 ? 103.244 108.078 144.187 1.00 95.21  ? 266 HIS B CB  1 
ATOM 5919 C CG  . HIS C 3 276 ? 102.083 108.444 143.316 1.00 96.86  ? 266 HIS B CG  1 
ATOM 5920 N ND1 . HIS C 3 276 ? 102.150 108.426 141.939 1.00 95.55  ? 266 HIS B ND1 1 
ATOM 5921 C CD2 . HIS C 3 276 ? 100.825 108.840 143.625 1.00 96.38  ? 266 HIS B CD2 1 
ATOM 5922 C CE1 . HIS C 3 276 ? 100.985 108.795 141.438 1.00 93.78  ? 266 HIS B CE1 1 
ATOM 5923 N NE2 . HIS C 3 276 ? 100.163 109.052 142.440 1.00 94.78  ? 266 HIS B NE2 1 
ATOM 5924 N N   . ASP C 3 277 ? 102.599 105.116 142.987 1.00 109.04 ? 267 ASP B N   1 
ATOM 5925 C CA  . ASP C 3 277 ? 102.876 104.035 142.046 1.00 108.11 ? 267 ASP B CA  1 
ATOM 5926 C C   . ASP C 3 277 ? 103.788 104.484 140.912 1.00 107.75 ? 267 ASP B C   1 
ATOM 5927 O O   . ASP C 3 277 ? 104.542 103.669 140.368 1.00 106.56 ? 267 ASP B O   1 
ATOM 5928 C CB  . ASP C 3 277 ? 101.566 103.483 141.486 1.00 110.49 ? 267 ASP B CB  1 
ATOM 5929 C CG  . ASP C 3 277 ? 101.679 102.033 141.066 1.00 110.92 ? 267 ASP B CG  1 
ATOM 5930 O OD1 . ASP C 3 277 ? 102.759 101.440 141.266 1.00 110.45 ? 267 ASP B OD1 1 
ATOM 5931 O OD2 . ASP C 3 277 ? 100.688 101.485 140.539 1.00 109.74 ? 267 ASP B OD2 1 
ATOM 5932 N N   . ASN C 3 278 ? 103.739 105.763 140.542 1.00 106.59 ? 268 ASN B N   1 
ATOM 5933 C CA  . ASN C 3 278 ? 104.553 106.271 139.446 1.00 107.96 ? 268 ASN B CA  1 
ATOM 5934 C C   . ASN C 3 278 ? 105.987 106.569 139.872 1.00 107.46 ? 268 ASN B C   1 
ATOM 5935 O O   . ASN C 3 278 ? 106.822 106.862 139.010 1.00 105.74 ? 268 ASN B O   1 
ATOM 5936 C CB  . ASN C 3 278 ? 103.898 107.533 138.864 1.00 108.17 ? 268 ASN B CB  1 
ATOM 5937 C CG  . ASN C 3 278 ? 104.413 107.894 137.472 1.00 109.41 ? 268 ASN B CG  1 
ATOM 5938 O OD1 . ASN C 3 278 ? 103.662 108.417 136.649 1.00 109.58 ? 268 ASN B OD1 1 
ATOM 5939 N ND2 . ASN C 3 278 ? 105.682 107.615 137.202 1.00 107.96 ? 268 ASN B ND2 1 
ATOM 5940 N N   . ILE C 3 279 ? 106.293 106.496 141.162 1.00 101.08 ? 269 ILE B N   1 
ATOM 5941 C CA  . ILE C 3 279 ? 107.624 106.814 141.667 1.00 101.48 ? 269 ILE B CA  1 
ATOM 5942 C C   . ILE C 3 279 ? 108.490 105.562 141.614 1.00 100.93 ? 269 ILE B C   1 
ATOM 5943 O O   . ILE C 3 279 ? 108.113 104.510 142.143 1.00 98.12  ? 269 ILE B O   1 
ATOM 5944 C CB  . ILE C 3 279 ? 107.550 107.374 143.096 1.00 99.54  ? 269 ILE B CB  1 
ATOM 5945 C CG1 . ILE C 3 279 ? 106.634 108.598 143.140 1.00 98.11  ? 269 ILE B CG1 1 
ATOM 5946 C CG2 . ILE C 3 279 ? 108.936 107.736 143.597 1.00 98.05  ? 269 ILE B CG2 1 
ATOM 5947 C CD1 . ILE C 3 279 ? 107.188 109.802 142.412 1.00 97.92  ? 269 ILE B CD1 1 
ATOM 5948 N N   . ILE C 3 280 ? 109.656 105.677 140.974 1.00 98.28  ? 270 ILE B N   1 
ATOM 5949 C CA  . ILE C 3 280 ? 110.594 104.573 140.841 1.00 97.86  ? 270 ILE B CA  1 
ATOM 5950 C C   . ILE C 3 280 ? 111.893 104.837 141.590 1.00 98.85  ? 270 ILE B C   1 
ATOM 5951 O O   . ILE C 3 280 ? 112.403 103.954 142.288 1.00 96.38  ? 270 ILE B O   1 
ATOM 5952 C CB  . ILE C 3 280 ? 110.884 104.264 139.356 1.00 99.00  ? 270 ILE B CB  1 
ATOM 5953 C CG1 . ILE C 3 280 ? 109.583 104.225 138.551 1.00 98.56  ? 270 ILE B CG1 1 
ATOM 5954 C CG2 . ILE C 3 280 ? 111.639 102.951 139.222 1.00 98.25  ? 270 ILE B CG2 1 
ATOM 5955 C CD1 . ILE C 3 280 ? 108.673 103.072 138.917 1.00 97.77  ? 270 ILE B CD1 1 
ATOM 5956 N N   . CYS C 3 281 ? 112.445 106.038 141.461 1.00 82.59  ? 271 CYS B N   1 
ATOM 5957 C CA  . CYS C 3 281 ? 113.709 106.384 142.091 1.00 80.38  ? 271 CYS B CA  1 
ATOM 5958 C C   . CYS C 3 281 ? 113.492 106.838 143.531 1.00 77.14  ? 271 CYS B C   1 
ATOM 5959 O O   . CYS C 3 281 ? 112.410 107.288 143.913 1.00 77.86  ? 271 CYS B O   1 
ATOM 5960 C CB  . CYS C 3 281 ? 114.418 107.479 141.299 1.00 77.40  ? 271 CYS B CB  1 
ATOM 5961 S SG  . CYS C 3 281 ? 113.293 108.655 140.535 1.00 80.32  ? 271 CYS B SG  1 
ATOM 5962 N N   . GLY C 3 282 ? 114.553 106.730 144.327 1.00 55.41  ? 272 GLY B N   1 
ATOM 5963 C CA  . GLY C 3 282 ? 114.475 107.016 145.741 1.00 53.80  ? 272 GLY B CA  1 
ATOM 5964 C C   . GLY C 3 282 ? 114.482 108.499 146.054 1.00 59.38  ? 272 GLY B C   1 
ATOM 5965 O O   . GLY C 3 282 ? 114.549 109.361 145.180 1.00 64.73  ? 272 GLY B O   1 
ATOM 5966 N N   . ILE C 3 283 ? 114.408 108.791 147.350 1.00 47.95  ? 273 ILE B N   1 
ATOM 5967 C CA  . ILE C 3 283 ? 114.368 110.156 147.859 1.00 35.20  ? 273 ILE B CA  1 
ATOM 5968 C C   . ILE C 3 283 ? 115.768 110.557 148.297 1.00 40.69  ? 273 ILE B C   1 
ATOM 5969 O O   . ILE C 3 283 ? 116.437 109.810 149.022 1.00 49.12  ? 273 ILE B O   1 
ATOM 5970 C CB  . ILE C 3 283 ? 113.372 110.287 149.023 1.00 31.82  ? 273 ILE B CB  1 
ATOM 5971 C CG1 . ILE C 3 283 ? 111.939 110.164 148.514 1.00 40.57  ? 273 ILE B CG1 1 
ATOM 5972 C CG2 . ILE C 3 283 ? 113.563 111.608 149.732 1.00 40.16  ? 273 ILE B CG2 1 
ATOM 5973 C CD1 . ILE C 3 283 ? 111.357 108.781 148.655 1.00 46.00  ? 273 ILE B CD1 1 
ATOM 5974 N N   . THR C 3 284 ? 116.213 111.733 147.860 1.00 39.57  ? 274 THR B N   1 
ATOM 5975 C CA  . THR C 3 284 ? 117.536 112.224 148.223 1.00 38.90  ? 274 THR B CA  1 
ATOM 5976 C C   . THR C 3 284 ? 117.503 113.137 149.444 1.00 51.58  ? 274 THR B C   1 
ATOM 5977 O O   . THR C 3 284 ? 118.393 113.058 150.297 1.00 59.46  ? 274 THR B O   1 
ATOM 5978 C CB  . THR C 3 284 ? 118.165 112.966 147.042 1.00 37.00  ? 274 THR B CB  1 
ATOM 5979 O OG1 . THR C 3 284 ? 118.157 112.119 145.888 1.00 47.52  ? 274 THR B OG1 1 
ATOM 5980 C CG2 . THR C 3 284 ? 119.596 113.352 147.361 1.00 42.79  ? 274 THR B CG2 1 
ATOM 5981 N N   . SER C 3 285 ? 116.498 114.002 149.548 1.00 44.24  ? 275 SER B N   1 
ATOM 5982 C CA  . SER C 3 285 ? 116.398 114.939 150.656 1.00 30.46  ? 275 SER B CA  1 
ATOM 5983 C C   . SER C 3 285 ? 114.945 115.079 151.084 1.00 37.53  ? 275 SER B C   1 
ATOM 5984 O O   . SER C 3 285 ? 114.030 115.011 150.261 1.00 48.77  ? 275 SER B O   1 
ATOM 5985 C CB  . SER C 3 285 ? 116.975 116.303 150.280 1.00 36.35  ? 275 SER B CB  1 
ATOM 5986 O OG  . SER C 3 285 ? 116.146 116.948 149.336 1.00 50.82  ? 275 SER B OG  1 
ATOM 5987 N N   . VAL C 3 286 ? 114.746 115.282 152.385 1.00 31.57  ? 276 VAL B N   1 
ATOM 5988 C CA  . VAL C 3 286 ? 113.421 115.377 152.987 1.00 25.09  ? 276 VAL B CA  1 
ATOM 5989 C C   . VAL C 3 286 ? 113.370 116.630 153.849 1.00 39.09  ? 276 VAL B C   1 
ATOM 5990 O O   . VAL C 3 286 ? 114.299 116.894 154.621 1.00 51.05  ? 276 VAL B O   1 
ATOM 5991 C CB  . VAL C 3 286 ? 113.090 114.127 153.824 1.00 23.04  ? 276 VAL B CB  1 
ATOM 5992 C CG1 . VAL C 3 286 ? 111.987 114.420 154.818 1.00 23.47  ? 276 VAL B CG1 1 
ATOM 5993 C CG2 . VAL C 3 286 ? 112.691 112.983 152.922 1.00 30.24  ? 276 VAL B CG2 1 
ATOM 5994 N N   . SER C 3 287 ? 112.292 117.402 153.716 1.00 40.42  ? 277 SER B N   1 
ATOM 5995 C CA  . SER C 3 287 ? 112.098 118.590 154.534 1.00 38.05  ? 277 SER B CA  1 
ATOM 5996 C C   . SER C 3 287 ? 110.610 118.789 154.781 1.00 40.33  ? 277 SER B C   1 
ATOM 5997 O O   . SER C 3 287 ? 109.765 118.293 154.033 1.00 49.27  ? 277 SER B O   1 
ATOM 5998 C CB  . SER C 3 287 ? 112.702 119.832 153.875 1.00 37.16  ? 277 SER B CB  1 
ATOM 5999 O OG  . SER C 3 287 ? 112.571 119.769 152.467 1.00 46.44  ? 277 SER B OG  1 
ATOM 6000 N N   . PHE C 3 288 ? 110.302 119.527 155.842 1.00 37.09  ? 278 PHE B N   1 
ATOM 6001 C CA  . PHE C 3 288 ? 108.938 119.835 156.245 1.00 35.08  ? 278 PHE B CA  1 
ATOM 6002 C C   . PHE C 3 288 ? 108.640 121.309 155.987 1.00 47.50  ? 278 PHE B C   1 
ATOM 6003 O O   . PHE C 3 288 ? 109.497 122.076 155.543 1.00 56.91  ? 278 PHE B O   1 
ATOM 6004 C CB  . PHE C 3 288 ? 108.725 119.500 157.722 1.00 37.41  ? 278 PHE B CB  1 
ATOM 6005 C CG  . PHE C 3 288 ? 108.138 118.140 157.963 1.00 40.63  ? 278 PHE B CG  1 
ATOM 6006 C CD1 . PHE C 3 288 ? 106.808 117.886 157.688 1.00 48.75  ? 278 PHE B CD1 1 
ATOM 6007 C CD2 . PHE C 3 288 ? 108.914 117.122 158.486 1.00 39.32  ? 278 PHE B CD2 1 
ATOM 6008 C CE1 . PHE C 3 288 ? 106.267 116.638 157.918 1.00 49.60  ? 278 PHE B CE1 1 
ATOM 6009 C CE2 . PHE C 3 288 ? 108.377 115.874 158.719 1.00 34.85  ? 278 PHE B CE2 1 
ATOM 6010 C CZ  . PHE C 3 288 ? 107.053 115.632 158.433 1.00 39.47  ? 278 PHE B CZ  1 
ATOM 6011 N N   . SER C 3 289 ? 107.403 121.700 156.270 1.00 55.22  ? 279 SER B N   1 
ATOM 6012 C CA  . SER C 3 289 ? 107.002 123.098 156.283 1.00 51.88  ? 279 SER B CA  1 
ATOM 6013 C C   . SER C 3 289 ? 106.925 123.596 157.723 1.00 57.34  ? 279 SER B C   1 
ATOM 6014 O O   . SER C 3 289 ? 107.000 122.821 158.678 1.00 58.08  ? 279 SER B O   1 
ATOM 6015 C CB  . SER C 3 289 ? 105.658 123.287 155.576 1.00 55.94  ? 279 SER B CB  1 
ATOM 6016 O OG  . SER C 3 289 ? 104.936 124.369 156.139 1.00 54.86  ? 279 SER B OG  1 
ATOM 6017 N N   . LYS C 3 290 ? 106.769 124.914 157.871 1.00 64.88  ? 280 LYS B N   1 
ATOM 6018 C CA  . LYS C 3 290 ? 106.755 125.504 159.207 1.00 63.25  ? 280 LYS B CA  1 
ATOM 6019 C C   . LYS C 3 290 ? 105.592 124.974 160.035 1.00 65.37  ? 280 LYS B C   1 
ATOM 6020 O O   . LYS C 3 290 ? 105.754 124.673 161.223 1.00 68.00  ? 280 LYS B O   1 
ATOM 6021 C CB  . LYS C 3 290 ? 106.696 127.028 159.116 1.00 62.40  ? 280 LYS B CB  1 
ATOM 6022 C CG  . LYS C 3 290 ? 106.750 127.718 160.471 1.00 64.48  ? 280 LYS B CG  1 
ATOM 6023 C CD  . LYS C 3 290 ? 106.759 129.230 160.335 1.00 63.79  ? 280 LYS B CD  1 
ATOM 6024 C CE  . LYS C 3 290 ? 106.799 129.900 161.699 1.00 66.40  ? 280 LYS B CE  1 
ATOM 6025 N NZ  . LYS C 3 290 ? 106.811 131.385 161.589 1.00 67.56  ? 280 LYS B NZ  1 
ATOM 6026 N N   . SER C 3 291 ? 104.410 124.854 159.428 1.00 64.38  ? 281 SER B N   1 
ATOM 6027 C CA  . SER C 3 291 ? 103.280 124.263 160.137 1.00 66.15  ? 281 SER B CA  1 
ATOM 6028 C C   . SER C 3 291 ? 103.460 122.766 160.340 1.00 67.26  ? 281 SER B C   1 
ATOM 6029 O O   . SER C 3 291 ? 103.018 122.224 161.359 1.00 65.55  ? 281 SER B O   1 
ATOM 6030 C CB  . SER C 3 291 ? 101.981 124.532 159.381 1.00 66.39  ? 281 SER B CB  1 
ATOM 6031 O OG  . SER C 3 291 ? 101.686 125.916 159.357 1.00 67.30  ? 281 SER B OG  1 
ATOM 6032 N N   . GLY C 3 292 ? 104.102 122.089 159.394 1.00 62.45  ? 282 GLY B N   1 
ATOM 6033 C CA  . GLY C 3 292 ? 104.183 120.645 159.426 1.00 59.81  ? 282 GLY B CA  1 
ATOM 6034 C C   . GLY C 3 292 ? 103.134 119.945 158.597 1.00 59.70  ? 282 GLY B C   1 
ATOM 6035 O O   . GLY C 3 292 ? 102.738 118.824 158.934 1.00 59.59  ? 282 GLY B O   1 
ATOM 6036 N N   . ARG C 3 293 ? 102.668 120.570 157.518 1.00 60.04  ? 283 ARG B N   1 
ATOM 6037 C CA  . ARG C 3 293 ? 101.644 119.998 156.654 1.00 57.75  ? 283 ARG B CA  1 
ATOM 6038 C C   . ARG C 3 293 ? 102.183 119.528 155.314 1.00 57.19  ? 283 ARG B C   1 
ATOM 6039 O O   . ARG C 3 293 ? 101.713 118.520 154.786 1.00 68.90  ? 283 ARG B O   1 
ATOM 6040 C CB  . ARG C 3 293 ? 100.523 121.017 156.414 1.00 58.29  ? 283 ARG B CB  1 
ATOM 6041 C CG  . ARG C 3 293 ? 99.377  120.484 155.573 1.00 59.83  ? 283 ARG B CG  1 
ATOM 6042 C CD  . ARG C 3 293 ? 98.250  119.978 156.452 1.00 57.60  ? 283 ARG B CD  1 
ATOM 6043 N NE  . ARG C 3 293 ? 97.211  119.308 155.681 1.00 56.40  ? 283 ARG B NE  1 
ATOM 6044 C CZ  . ARG C 3 293 ? 95.988  119.063 156.129 1.00 64.18  ? 283 ARG B CZ  1 
ATOM 6045 N NH1 . ARG C 3 293 ? 95.610  119.431 157.342 1.00 64.37  ? 283 ARG B NH1 1 
ATOM 6046 N NH2 . ARG C 3 293 ? 95.122  118.434 155.340 1.00 69.58  ? 283 ARG B NH2 1 
ATOM 6047 N N   . LEU C 3 294 ? 103.159 120.229 154.750 1.00 40.18  ? 284 LEU B N   1 
ATOM 6048 C CA  . LEU C 3 294 ? 103.767 119.842 153.485 1.00 44.23  ? 284 LEU B CA  1 
ATOM 6049 C C   . LEU C 3 294 ? 105.090 119.143 153.764 1.00 49.34  ? 284 LEU B C   1 
ATOM 6050 O O   . LEU C 3 294 ? 105.973 119.714 154.411 1.00 59.48  ? 284 LEU B O   1 
ATOM 6051 C CB  . LEU C 3 294 ? 103.983 121.059 152.587 1.00 46.99  ? 284 LEU B CB  1 
ATOM 6052 C CG  . LEU C 3 294 ? 102.757 121.921 152.293 1.00 52.63  ? 284 LEU B CG  1 
ATOM 6053 C CD1 . LEU C 3 294 ? 103.132 123.050 151.351 1.00 60.29  ? 284 LEU B CD1 1 
ATOM 6054 C CD2 . LEU C 3 294 ? 101.633 121.085 151.711 1.00 54.04  ? 284 LEU B CD2 1 
ATOM 6055 N N   . LEU C 3 295 ? 105.223 117.913 153.282 1.00 47.59  ? 285 LEU B N   1 
ATOM 6056 C CA  . LEU C 3 295 ? 106.453 117.139 153.410 1.00 35.59  ? 285 LEU B CA  1 
ATOM 6057 C C   . LEU C 3 295 ? 107.111 117.115 152.033 1.00 33.31  ? 285 LEU B C   1 
ATOM 6058 O O   . LEU C 3 295 ? 106.798 116.273 151.190 1.00 40.40  ? 285 LEU B O   1 
ATOM 6059 C CB  . LEU C 3 295 ? 106.171 115.734 153.939 1.00 33.88  ? 285 LEU B CB  1 
ATOM 6060 C CG  . LEU C 3 295 ? 107.314 114.721 153.858 1.00 36.84  ? 285 LEU B CG  1 
ATOM 6061 C CD1 . LEU C 3 295 ? 108.501 115.221 154.644 1.00 46.42  ? 285 LEU B CD1 1 
ATOM 6062 C CD2 . LEU C 3 295 ? 106.868 113.371 154.377 1.00 38.75  ? 285 LEU B CD2 1 
ATOM 6063 N N   . LEU C 3 296 ? 108.014 118.061 151.803 1.00 30.91  ? 286 LEU B N   1 
ATOM 6064 C CA  . LEU C 3 296 ? 108.710 118.154 150.528 1.00 40.28  ? 286 LEU B CA  1 
ATOM 6065 C C   . LEU C 3 296 ? 109.835 117.129 150.474 1.00 46.20  ? 286 LEU B C   1 
ATOM 6066 O O   . LEU C 3 296 ? 110.609 116.995 151.425 1.00 52.54  ? 286 LEU B O   1 
ATOM 6067 C CB  . LEU C 3 296 ? 109.263 119.563 150.326 1.00 35.51  ? 286 LEU B CB  1 
ATOM 6068 C CG  . LEU C 3 296 ? 108.231 120.671 150.111 1.00 42.53  ? 286 LEU B CG  1 
ATOM 6069 C CD1 . LEU C 3 296 ? 107.917 121.382 151.417 1.00 47.25  ? 286 LEU B CD1 1 
ATOM 6070 C CD2 . LEU C 3 296 ? 108.725 121.655 149.067 1.00 46.23  ? 286 LEU B CD2 1 
ATOM 6071 N N   . ALA C 3 297 ? 109.924 116.409 149.359 1.00 43.05  ? 287 ALA B N   1 
ATOM 6072 C CA  . ALA C 3 297 ? 110.933 115.377 149.180 1.00 31.35  ? 287 ALA B CA  1 
ATOM 6073 C C   . ALA C 3 297 ? 111.526 115.485 147.785 1.00 35.10  ? 287 ALA B C   1 
ATOM 6074 O O   . ALA C 3 297 ? 110.802 115.713 146.813 1.00 49.53  ? 287 ALA B O   1 
ATOM 6075 C CB  . ALA C 3 297 ? 110.345 113.978 149.394 1.00 40.31  ? 287 ALA B CB  1 
ATOM 6076 N N   . GLY C 3 298 ? 112.840 115.322 147.692 1.00 35.91  ? 288 GLY B N   1 
ATOM 6077 C CA  . GLY C 3 298 ? 113.542 115.382 146.421 1.00 39.67  ? 288 GLY B CA  1 
ATOM 6078 C C   . GLY C 3 298 ? 113.901 113.990 145.932 1.00 54.26  ? 288 GLY B C   1 
ATOM 6079 O O   . GLY C 3 298 ? 114.409 113.166 146.691 1.00 62.63  ? 288 GLY B O   1 
ATOM 6080 N N   . TYR C 3 299 ? 113.639 113.743 144.655 1.00 59.73  ? 289 TYR B N   1 
ATOM 6081 C CA  . TYR C 3 299 ? 113.855 112.446 144.032 1.00 55.67  ? 289 TYR B CA  1 
ATOM 6082 C C   . TYR C 3 299 ? 115.011 112.526 143.043 1.00 61.60  ? 289 TYR B C   1 
ATOM 6083 O O   . TYR C 3 299 ? 115.595 113.587 142.810 1.00 68.43  ? 289 TYR B O   1 
ATOM 6084 C CB  . TYR C 3 299 ? 112.580 111.966 143.336 1.00 52.32  ? 289 TYR B CB  1 
ATOM 6085 C CG  . TYR C 3 299 ? 111.369 111.902 144.235 1.00 53.91  ? 289 TYR B CG  1 
ATOM 6086 C CD1 . TYR C 3 299 ? 111.068 110.748 144.941 1.00 53.68  ? 289 TYR B CD1 1 
ATOM 6087 C CD2 . TYR C 3 299 ? 110.532 112.996 144.382 1.00 57.59  ? 289 TYR B CD2 1 
ATOM 6088 C CE1 . TYR C 3 299 ? 109.964 110.683 145.761 1.00 53.60  ? 289 TYR B CE1 1 
ATOM 6089 C CE2 . TYR C 3 299 ? 109.428 112.940 145.203 1.00 58.08  ? 289 TYR B CE2 1 
ATOM 6090 C CZ  . TYR C 3 299 ? 109.149 111.782 145.890 1.00 59.39  ? 289 TYR B CZ  1 
ATOM 6091 O OH  . TYR C 3 299 ? 108.048 111.721 146.711 1.00 69.76  ? 289 TYR B OH  1 
ATOM 6092 N N   . ASP C 3 300 ? 115.341 111.376 142.458 1.00 69.04  ? 290 ASP B N   1 
ATOM 6093 C CA  . ASP C 3 300 ? 116.373 111.297 141.436 1.00 69.42  ? 290 ASP B CA  1 
ATOM 6094 C C   . ASP C 3 300 ? 115.839 111.550 140.032 1.00 75.50  ? 290 ASP B C   1 
ATOM 6095 O O   . ASP C 3 300 ? 116.636 111.640 139.091 1.00 75.75  ? 290 ASP B O   1 
ATOM 6096 C CB  . ASP C 3 300 ? 117.061 109.927 141.479 1.00 71.55  ? 290 ASP B CB  1 
ATOM 6097 C CG  . ASP C 3 300 ? 117.351 109.463 142.893 1.00 72.50  ? 290 ASP B CG  1 
ATOM 6098 O OD1 . ASP C 3 300 ? 118.373 109.891 143.465 1.00 74.19  ? 290 ASP B OD1 1 
ATOM 6099 O OD2 . ASP C 3 300 ? 116.562 108.658 143.431 1.00 69.80  ? 290 ASP B OD2 1 
ATOM 6100 N N   . ASP C 3 301 ? 114.519 111.674 139.866 1.00 77.13  ? 291 ASP B N   1 
ATOM 6101 C CA  . ASP C 3 301 ? 113.914 111.968 138.572 1.00 75.40  ? 291 ASP B CA  1 
ATOM 6102 C C   . ASP C 3 301 ? 113.801 113.464 138.301 1.00 78.43  ? 291 ASP B C   1 
ATOM 6103 O O   . ASP C 3 301 ? 112.920 113.890 137.543 1.00 75.55  ? 291 ASP B O   1 
ATOM 6104 C CB  . ASP C 3 301 ? 112.547 111.289 138.456 1.00 76.33  ? 291 ASP B CB  1 
ATOM 6105 C CG  . ASP C 3 301 ? 111.609 111.650 139.592 1.00 80.08  ? 291 ASP B CG  1 
ATOM 6106 O OD1 . ASP C 3 301 ? 111.703 112.773 140.121 1.00 81.16  ? 291 ASP B OD1 1 
ATOM 6107 O OD2 . ASP C 3 301 ? 110.767 110.802 139.955 1.00 83.46  ? 291 ASP B OD2 1 
ATOM 6108 N N   . PHE C 3 302 ? 114.655 114.267 138.931 1.00 82.12  ? 292 PHE B N   1 
ATOM 6109 C CA  . PHE C 3 302 ? 114.928 115.675 138.647 1.00 80.04  ? 292 PHE B CA  1 
ATOM 6110 C C   . PHE C 3 302 ? 113.862 116.617 139.201 1.00 83.28  ? 292 PHE B C   1 
ATOM 6111 O O   . PHE C 3 302 ? 113.981 117.830 138.992 1.00 84.23  ? 292 PHE B O   1 
ATOM 6112 C CB  . PHE C 3 302 ? 115.090 115.967 137.144 1.00 81.01  ? 292 PHE B CB  1 
ATOM 6113 C CG  . PHE C 3 302 ? 116.058 115.052 136.431 1.00 84.25  ? 292 PHE B CG  1 
ATOM 6114 C CD1 . PHE C 3 302 ? 116.980 114.287 137.130 1.00 82.61  ? 292 PHE B CD1 1 
ATOM 6115 C CD2 . PHE C 3 302 ? 116.038 114.959 135.049 1.00 84.57  ? 292 PHE B CD2 1 
ATOM 6116 C CE1 . PHE C 3 302 ? 117.859 113.452 136.467 1.00 83.30  ? 292 PHE B CE1 1 
ATOM 6117 C CE2 . PHE C 3 302 ? 116.915 114.125 134.380 1.00 85.21  ? 292 PHE B CE2 1 
ATOM 6118 C CZ  . PHE C 3 302 ? 117.827 113.371 135.091 1.00 83.60  ? 292 PHE B CZ  1 
ATOM 6119 N N   . ASN C 3 303 ? 112.838 116.125 139.894 1.00 74.13  ? 293 ASN B N   1 
ATOM 6120 C CA  . ASN C 3 303 ? 111.792 116.991 140.418 1.00 72.84  ? 293 ASN B CA  1 
ATOM 6121 C C   . ASN C 3 303 ? 111.491 116.644 141.871 1.00 72.47  ? 293 ASN B C   1 
ATOM 6122 O O   . ASN C 3 303 ? 111.867 115.581 142.371 1.00 73.80  ? 293 ASN B O   1 
ATOM 6123 C CB  . ASN C 3 303 ? 110.517 116.932 139.542 1.00 72.30  ? 293 ASN B CB  1 
ATOM 6124 C CG  . ASN C 3 303 ? 109.639 115.710 139.808 1.00 75.19  ? 293 ASN B CG  1 
ATOM 6125 O OD1 . ASN C 3 303 ? 110.013 114.778 140.514 1.00 74.24  ? 293 ASN B OD1 1 
ATOM 6126 N ND2 . ASN C 3 303 ? 108.448 115.721 139.221 1.00 80.40  ? 293 ASN B ND2 1 
ATOM 6127 N N   . CYS C 3 304 ? 110.820 117.571 142.548 1.00 65.89  ? 294 CYS B N   1 
ATOM 6128 C CA  . CYS C 3 304 ? 110.403 117.400 143.931 1.00 60.72  ? 294 CYS B CA  1 
ATOM 6129 C C   . CYS C 3 304 ? 108.884 117.359 144.006 1.00 59.46  ? 294 CYS B C   1 
ATOM 6130 O O   . CYS C 3 304 ? 108.200 118.112 143.307 1.00 69.21  ? 294 CYS B O   1 
ATOM 6131 C CB  . CYS C 3 304 ? 110.936 118.532 144.811 1.00 62.99  ? 294 CYS B CB  1 
ATOM 6132 S SG  . CYS C 3 304 ? 112.733 118.684 144.824 1.00 90.08  ? 294 CYS B SG  1 
ATOM 6133 N N   . ASN C 3 305 ? 108.360 116.480 144.854 1.00 59.83  ? 295 ASN B N   1 
ATOM 6134 C CA  . ASN C 3 305 ? 106.924 116.319 145.032 1.00 64.07  ? 295 ASN B CA  1 
ATOM 6135 C C   . ASN C 3 305 ? 106.545 116.747 146.440 1.00 63.96  ? 295 ASN B C   1 
ATOM 6136 O O   . ASN C 3 305 ? 107.158 116.299 147.414 1.00 68.76  ? 295 ASN B O   1 
ATOM 6137 C CB  . ASN C 3 305 ? 106.495 114.872 144.782 1.00 65.94  ? 295 ASN B CB  1 
ATOM 6138 C CG  . ASN C 3 305 ? 106.864 114.386 143.394 1.00 69.33  ? 295 ASN B CG  1 
ATOM 6139 O OD1 . ASN C 3 305 ? 107.325 115.159 142.556 1.00 68.95  ? 295 ASN B OD1 1 
ATOM 6140 N ND2 . ASN C 3 305 ? 106.658 113.100 143.144 1.00 73.48  ? 295 ASN B ND2 1 
ATOM 6141 N N   . VAL C 3 306 ? 105.535 117.603 146.545 1.00 60.76  ? 296 VAL B N   1 
ATOM 6142 C CA  . VAL C 3 306 ? 105.078 118.121 147.828 1.00 59.45  ? 296 VAL B CA  1 
ATOM 6143 C C   . VAL C 3 306 ? 103.976 117.202 148.339 1.00 62.83  ? 296 VAL B C   1 
ATOM 6144 O O   . VAL C 3 306 ? 102.896 117.124 147.749 1.00 72.68  ? 296 VAL B O   1 
ATOM 6145 C CB  . VAL C 3 306 ? 104.584 119.566 147.706 1.00 63.47  ? 296 VAL B CB  1 
ATOM 6146 C CG1 . VAL C 3 306 ? 104.155 120.095 149.062 1.00 60.55  ? 296 VAL B CG1 1 
ATOM 6147 C CG2 . VAL C 3 306 ? 105.668 120.443 147.103 1.00 65.08  ? 296 VAL B CG2 1 
ATOM 6148 N N   . TRP C 3 307 ? 104.244 116.510 149.441 1.00 61.13  ? 297 TRP B N   1 
ATOM 6149 C CA  . TRP C 3 307 ? 103.311 115.551 150.016 1.00 58.94  ? 297 TRP B CA  1 
ATOM 6150 C C   . TRP C 3 307 ? 102.584 116.190 151.189 1.00 53.99  ? 297 TRP B C   1 
ATOM 6151 O O   . TRP C 3 307 ? 103.221 116.663 152.135 1.00 69.74  ? 297 TRP B O   1 
ATOM 6152 C CB  . TRP C 3 307 ? 104.038 114.287 150.471 1.00 60.24  ? 297 TRP B CB  1 
ATOM 6153 C CG  . TRP C 3 307 ? 104.716 113.550 149.366 1.00 63.43  ? 297 TRP B CG  1 
ATOM 6154 C CD1 . TRP C 3 307 ? 105.971 113.767 148.883 1.00 63.83  ? 297 TRP B CD1 1 
ATOM 6155 C CD2 . TRP C 3 307 ? 104.175 112.465 148.608 1.00 59.52  ? 297 TRP B CD2 1 
ATOM 6156 N NE1 . TRP C 3 307 ? 106.244 112.887 147.866 1.00 62.00  ? 297 TRP B NE1 1 
ATOM 6157 C CE2 . TRP C 3 307 ? 105.156 112.076 147.677 1.00 60.96  ? 297 TRP B CE2 1 
ATOM 6158 C CE3 . TRP C 3 307 ? 102.953 111.787 148.623 1.00 58.07  ? 297 TRP B CE3 1 
ATOM 6159 C CZ2 . TRP C 3 307 ? 104.955 111.039 146.772 1.00 62.29  ? 297 TRP B CZ2 1 
ATOM 6160 C CZ3 . TRP C 3 307 ? 102.756 110.758 147.725 1.00 66.13  ? 297 TRP B CZ3 1 
ATOM 6161 C CH2 . TRP C 3 307 ? 103.751 110.394 146.812 1.00 67.79  ? 297 TRP B CH2 1 
ATOM 6162 N N   . ASP C 3 308 ? 101.256 116.198 151.130 1.00 47.89  ? 298 ASP B N   1 
ATOM 6163 C CA  . ASP C 3 308 ? 100.457 116.645 152.263 1.00 53.60  ? 298 ASP B CA  1 
ATOM 6164 C C   . ASP C 3 308 ? 100.637 115.646 153.399 1.00 57.58  ? 298 ASP B C   1 
ATOM 6165 O O   . ASP C 3 308 ? 100.163 114.509 153.317 1.00 67.52  ? 298 ASP B O   1 
ATOM 6166 C CB  . ASP C 3 308 ? 98.993  116.778 151.857 1.00 58.48  ? 298 ASP B CB  1 
ATOM 6167 C CG  . ASP C 3 308 ? 98.051  116.688 153.036 1.00 66.19  ? 298 ASP B CG  1 
ATOM 6168 O OD1 . ASP C 3 308 ? 97.909  117.693 153.764 1.00 72.31  ? 298 ASP B OD1 1 
ATOM 6169 O OD2 . ASP C 3 308 ? 97.452  115.614 153.238 1.00 62.26  ? 298 ASP B OD2 1 
ATOM 6170 N N   . ALA C 3 309 ? 101.325 116.069 154.459 1.00 52.92  ? 299 ALA B N   1 
ATOM 6171 C CA  . ALA C 3 309 ? 101.818 115.164 155.493 1.00 51.66  ? 299 ALA B CA  1 
ATOM 6172 C C   . ALA C 3 309 ? 100.719 114.523 156.327 1.00 53.98  ? 299 ALA B C   1 
ATOM 6173 O O   . ALA C 3 309 ? 101.044 113.802 157.276 1.00 63.66  ? 299 ALA B O   1 
ATOM 6174 C CB  . ALA C 3 309 ? 102.786 115.905 156.416 1.00 51.96  ? 299 ALA B CB  1 
ATOM 6175 N N   . LEU C 3 310 ? 99.443  114.756 156.022 1.00 58.12  ? 300 LEU B N   1 
ATOM 6176 C CA  . LEU C 3 310 ? 98.361  114.168 156.794 1.00 64.88  ? 300 LEU B CA  1 
ATOM 6177 C C   . LEU C 3 310 ? 97.452  113.245 155.997 1.00 68.97  ? 300 LEU B C   1 
ATOM 6178 O O   . LEU C 3 310 ? 96.729  112.452 156.608 1.00 67.19  ? 300 LEU B O   1 
ATOM 6179 C CB  . LEU C 3 310 ? 97.505  115.267 157.445 1.00 70.53  ? 300 LEU B CB  1 
ATOM 6180 C CG  . LEU C 3 310 ? 97.944  115.707 158.844 1.00 63.91  ? 300 LEU B CG  1 
ATOM 6181 C CD1 . LEU C 3 310 ? 99.220  116.529 158.784 1.00 60.97  ? 300 LEU B CD1 1 
ATOM 6182 C CD2 . LEU C 3 310 ? 96.840  116.485 159.539 1.00 66.12  ? 300 LEU B CD2 1 
ATOM 6183 N N   . LYS C 3 311 ? 97.463  113.314 154.663 1.00 78.55  ? 301 LYS B N   1 
ATOM 6184 C CA  . LYS C 3 311 ? 96.637  112.429 153.851 1.00 81.07  ? 301 LYS B CA  1 
ATOM 6185 C C   . LYS C 3 311 ? 97.421  111.715 152.755 1.00 77.32  ? 301 LYS B C   1 
ATOM 6186 O O   . LYS C 3 311 ? 96.833  110.920 152.014 1.00 79.00  ? 301 LYS B O   1 
ATOM 6187 C CB  . LYS C 3 311 ? 95.466  113.200 153.228 1.00 78.27  ? 301 LYS B CB  1 
ATOM 6188 C CG  . LYS C 3 311 ? 94.607  113.947 154.233 1.00 75.16  ? 301 LYS B CG  1 
ATOM 6189 C CD  . LYS C 3 311 ? 93.418  114.602 153.554 1.00 79.03  ? 301 LYS B CD  1 
ATOM 6190 C CE  . LYS C 3 311 ? 92.230  113.654 153.498 1.00 82.07  ? 301 LYS B CE  1 
ATOM 6191 N NZ  . LYS C 3 311 ? 91.568  113.498 154.821 1.00 83.84  ? 301 LYS B NZ  1 
ATOM 6192 N N   . ALA C 3 312 ? 98.728  111.960 152.645 1.00 61.70  ? 302 ALA B N   1 
ATOM 6193 C CA  . ALA C 3 312 ? 99.591  111.273 151.680 1.00 63.79  ? 302 ALA B CA  1 
ATOM 6194 C C   . ALA C 3 312 ? 99.108  111.462 150.243 1.00 66.19  ? 302 ALA B C   1 
ATOM 6195 O O   . ALA C 3 312 ? 99.076  110.517 149.452 1.00 72.02  ? 302 ALA B O   1 
ATOM 6196 C CB  . ALA C 3 312 ? 99.719  109.786 152.016 1.00 66.30  ? 302 ALA B CB  1 
ATOM 6197 N N   . ASP C 3 313 ? 98.725  112.689 149.900 1.00 66.89  ? 303 ASP B N   1 
ATOM 6198 C CA  . ASP C 3 313 ? 98.371  113.058 148.534 1.00 68.84  ? 303 ASP B CA  1 
ATOM 6199 C C   . ASP C 3 313 ? 99.362  114.089 148.018 1.00 73.19  ? 303 ASP B C   1 
ATOM 6200 O O   . ASP C 3 313 ? 99.700  115.040 148.730 1.00 77.37  ? 303 ASP B O   1 
ATOM 6201 C CB  . ASP C 3 313 ? 96.947  113.616 148.447 1.00 71.74  ? 303 ASP B CB  1 
ATOM 6202 C CG  . ASP C 3 313 ? 95.890  112.573 148.739 1.00 76.24  ? 303 ASP B CG  1 
ATOM 6203 O OD1 . ASP C 3 313 ? 96.180  111.620 149.487 1.00 75.11  ? 303 ASP B OD1 1 
ATOM 6204 O OD2 . ASP C 3 313 ? 94.764  112.708 148.215 1.00 76.73  ? 303 ASP B OD2 1 
ATOM 6205 N N   . ARG C 3 314 ? 99.821  113.900 146.784 1.00 75.72  ? 304 ARG B N   1 
ATOM 6206 C CA  . ARG C 3 314 ? 100.745 114.841 146.160 1.00 75.43  ? 304 ARG B CA  1 
ATOM 6207 C C   . ARG C 3 314 ? 100.027 116.160 145.911 1.00 73.54  ? 304 ARG B C   1 
ATOM 6208 O O   . ARG C 3 314 ? 99.206  116.266 144.995 1.00 77.13  ? 304 ARG B O   1 
ATOM 6209 C CB  . ARG C 3 314 ? 101.283 114.263 144.856 1.00 72.76  ? 304 ARG B CB  1 
ATOM 6210 C CG  . ARG C 3 314 ? 102.038 112.959 145.013 1.00 71.37  ? 304 ARG B CG  1 
ATOM 6211 C CD  . ARG C 3 314 ? 102.304 112.317 143.662 1.00 74.69  ? 304 ARG B CD  1 
ATOM 6212 N NE  . ARG C 3 314 ? 103.107 113.169 142.793 1.00 76.84  ? 304 ARG B NE  1 
ATOM 6213 C CZ  . ARG C 3 314 ? 103.736 112.747 141.705 1.00 78.81  ? 304 ARG B CZ  1 
ATOM 6214 N NH1 . ARG C 3 314 ? 103.671 111.484 141.316 1.00 77.73  ? 304 ARG B NH1 1 
ATOM 6215 N NH2 . ARG C 3 314 ? 104.448 113.612 140.989 1.00 73.20  ? 304 ARG B NH2 1 
ATOM 6216 N N   . ALA C 3 315 ? 100.327 117.167 146.725 1.00 77.31  ? 305 ALA B N   1 
ATOM 6217 C CA  . ALA C 3 315 ? 99.724  118.490 146.569 1.00 80.71  ? 305 ALA B CA  1 
ATOM 6218 C C   . ALA C 3 315 ? 100.589 119.405 145.707 1.00 79.25  ? 305 ALA B C   1 
ATOM 6219 O O   . ALA C 3 315 ? 100.926 120.520 146.098 1.00 82.47  ? 305 ALA B O   1 
ATOM 6220 C CB  . ALA C 3 315 ? 99.469  119.107 147.938 1.00 82.74  ? 305 ALA B CB  1 
ATOM 6221 N N   . GLY C 3 316 ? 100.948 118.939 144.520 1.00 73.21  ? 306 GLY B N   1 
ATOM 6222 C CA  . GLY C 3 316 ? 101.733 119.720 143.587 1.00 78.76  ? 306 GLY B CA  1 
ATOM 6223 C C   . GLY C 3 316 ? 103.099 119.107 143.330 1.00 80.93  ? 306 GLY B C   1 
ATOM 6224 O O   . GLY C 3 316 ? 103.540 118.178 144.002 1.00 80.82  ? 306 GLY B O   1 
ATOM 6225 N N   . VAL C 3 317 ? 103.760 119.662 142.317 1.00 75.66  ? 307 VAL B N   1 
ATOM 6226 C CA  . VAL C 3 317 ? 105.089 119.230 141.899 1.00 69.49  ? 307 VAL B CA  1 
ATOM 6227 C C   . VAL C 3 317 ? 105.918 120.470 141.596 1.00 73.48  ? 307 VAL B C   1 
ATOM 6228 O O   . VAL C 3 317 ? 105.446 121.385 140.914 1.00 78.17  ? 307 VAL B O   1 
ATOM 6229 C CB  . VAL C 3 317 ? 105.026 118.303 140.669 1.00 68.04  ? 307 VAL B CB  1 
ATOM 6230 C CG1 . VAL C 3 317 ? 106.374 118.239 139.969 1.00 66.52  ? 307 VAL B CG1 1 
ATOM 6231 C CG2 . VAL C 3 317 ? 104.572 116.914 141.078 1.00 70.45  ? 307 VAL B CG2 1 
ATOM 6232 N N   . LEU C 3 318 ? 107.154 120.501 142.098 1.00 75.15  ? 308 LEU B N   1 
ATOM 6233 C CA  . LEU C 3 318 ? 108.022 121.651 141.868 1.00 67.95  ? 308 LEU B CA  1 
ATOM 6234 C C   . LEU C 3 318 ? 108.635 121.616 140.472 1.00 69.23  ? 308 LEU B C   1 
ATOM 6235 O O   . LEU C 3 318 ? 108.479 122.560 139.690 1.00 69.84  ? 308 LEU B O   1 
ATOM 6236 C CB  . LEU C 3 318 ? 109.118 121.700 142.935 1.00 64.12  ? 308 LEU B CB  1 
ATOM 6237 C CG  . LEU C 3 318 ? 108.665 122.071 144.347 1.00 68.64  ? 308 LEU B CG  1 
ATOM 6238 C CD1 . LEU C 3 318 ? 109.839 122.054 145.310 1.00 71.97  ? 308 LEU B CD1 1 
ATOM 6239 C CD2 . LEU C 3 318 ? 108.001 123.430 144.339 1.00 69.60  ? 308 LEU B CD2 1 
ATOM 6240 N N   . ALA C 3 319 ? 109.337 120.534 140.150 1.00 72.93  ? 309 ALA B N   1 
ATOM 6241 C CA  . ALA C 3 319 ? 109.999 120.340 138.852 1.00 72.34  ? 309 ALA B CA  1 
ATOM 6242 C C   . ALA C 3 319 ? 111.005 121.474 138.641 1.00 73.93  ? 309 ALA B C   1 
ATOM 6243 O O   . ALA C 3 319 ? 111.516 122.054 139.607 1.00 77.81  ? 309 ALA B O   1 
ATOM 6244 C CB  . ALA C 3 319 ? 108.958 120.201 137.755 1.00 73.70  ? 309 ALA B CB  1 
ATOM 6245 N N   . GLY C 3 320 ? 111.314 121.786 137.382 1.00 70.10  ? 310 GLY B N   1 
ATOM 6246 C CA  . GLY C 3 320 ? 112.167 122.900 137.043 1.00 71.06  ? 310 GLY B CA  1 
ATOM 6247 C C   . GLY C 3 320 ? 113.645 122.582 136.950 1.00 74.83  ? 310 GLY B C   1 
ATOM 6248 O O   . GLY C 3 320 ? 114.387 123.344 136.321 1.00 72.93  ? 310 GLY B O   1 
ATOM 6249 N N   . HIS C 3 321 ? 114.096 121.486 137.550 1.00 74.86  ? 311 HIS B N   1 
ATOM 6250 C CA  . HIS C 3 321 ? 115.511 121.150 137.559 1.00 73.01  ? 311 HIS B CA  1 
ATOM 6251 C C   . HIS C 3 321 ? 115.863 120.209 136.415 1.00 72.28  ? 311 HIS B C   1 
ATOM 6252 O O   . HIS C 3 321 ? 115.038 119.413 135.958 1.00 72.55  ? 311 HIS B O   1 
ATOM 6253 C CB  . HIS C 3 321 ? 115.909 120.517 138.892 1.00 69.98  ? 311 HIS B CB  1 
ATOM 6254 C CG  . HIS C 3 321 ? 116.409 121.504 139.899 1.00 70.72  ? 311 HIS B CG  1 
ATOM 6255 N ND1 . HIS C 3 321 ? 117.581 122.209 139.730 1.00 65.25  ? 311 HIS B ND1 1 
ATOM 6256 C CD2 . HIS C 3 321 ? 115.891 121.911 141.081 1.00 74.44  ? 311 HIS B CD2 1 
ATOM 6257 C CE1 . HIS C 3 321 ? 117.767 123.004 140.768 1.00 67.48  ? 311 HIS B CE1 1 
ATOM 6258 N NE2 . HIS C 3 321 ? 116.755 122.843 141.602 1.00 75.49  ? 311 HIS B NE2 1 
ATOM 6259 N N   . ASP C 3 322 ? 117.110 120.309 135.959 1.00 87.49  ? 312 ASP B N   1 
ATOM 6260 C CA  . ASP C 3 322 ? 117.594 119.485 134.861 1.00 86.95  ? 312 ASP B CA  1 
ATOM 6261 C C   . ASP C 3 322 ? 118.225 118.183 135.333 1.00 87.05  ? 312 ASP B C   1 
ATOM 6262 O O   . ASP C 3 322 ? 118.229 117.199 134.584 1.00 87.66  ? 312 ASP B O   1 
ATOM 6263 C CB  . ASP C 3 322 ? 118.612 120.269 134.028 1.00 84.66  ? 312 ASP B CB  1 
ATOM 6264 C CG  . ASP C 3 322 ? 118.020 120.808 132.743 1.00 89.52  ? 312 ASP B CG  1 
ATOM 6265 O OD1 . ASP C 3 322 ? 117.173 120.116 132.141 1.00 94.28  ? 312 ASP B OD1 1 
ATOM 6266 O OD2 . ASP C 3 322 ? 118.400 121.925 132.334 1.00 91.20  ? 312 ASP B OD2 1 
ATOM 6267 N N   . ASN C 3 323 ? 118.758 118.150 136.554 1.00 82.28  ? 313 ASN B N   1 
ATOM 6268 C CA  . ASN C 3 323 ? 119.413 116.952 137.062 1.00 81.35  ? 313 ASN B CA  1 
ATOM 6269 C C   . ASN C 3 323 ? 118.861 116.561 138.427 1.00 79.30  ? 313 ASN B C   1 
ATOM 6270 O O   . ASN C 3 323 ? 117.876 117.142 138.895 1.00 83.88  ? 313 ASN B O   1 
ATOM 6271 C CB  . ASN C 3 323 ? 120.927 117.163 137.135 1.00 81.87  ? 313 ASN B CB  1 
ATOM 6272 C CG  . ASN C 3 323 ? 121.705 115.904 136.814 1.00 79.87  ? 313 ASN B CG  1 
ATOM 6273 O OD1 . ASN C 3 323 ? 121.140 114.814 136.740 1.00 82.27  ? 313 ASN B OD1 1 
ATOM 6274 N ND2 . ASN C 3 323 ? 123.008 116.050 136.611 1.00 78.78  ? 313 ASN B ND2 1 
ATOM 6275 N N   . ARG C 3 324 ? 119.484 115.573 139.067 1.00 70.68  ? 314 ARG B N   1 
ATOM 6276 C CA  . ARG C 3 324 ? 118.980 115.048 140.329 1.00 71.45  ? 314 ARG B CA  1 
ATOM 6277 C C   . ARG C 3 324 ? 119.024 116.107 141.423 1.00 72.53  ? 314 ARG B C   1 
ATOM 6278 O O   . ARG C 3 324 ? 120.041 116.777 141.615 1.00 72.89  ? 314 ARG B O   1 
ATOM 6279 C CB  . ARG C 3 324 ? 119.802 113.831 140.751 1.00 72.92  ? 314 ARG B CB  1 
ATOM 6280 C CG  . ARG C 3 324 ? 119.433 113.279 142.115 1.00 71.93  ? 314 ARG B CG  1 
ATOM 6281 C CD  . ARG C 3 324 ? 120.380 112.170 142.538 1.00 71.01  ? 314 ARG B CD  1 
ATOM 6282 N NE  . ARG C 3 324 ? 120.271 110.997 141.679 1.00 73.27  ? 314 ARG B NE  1 
ATOM 6283 C CZ  . ARG C 3 324 ? 121.005 109.901 141.813 1.00 72.84  ? 314 ARG B CZ  1 
ATOM 6284 N NH1 . ARG C 3 324 ? 121.909 109.788 142.772 1.00 71.29  ? 314 ARG B NH1 1 
ATOM 6285 N NH2 . ARG C 3 324 ? 120.826 108.893 140.965 1.00 73.13  ? 314 ARG B NH2 1 
ATOM 6286 N N   . VAL C 3 325 ? 117.920 116.239 142.153 1.00 62.28  ? 315 VAL B N   1 
ATOM 6287 C CA  . VAL C 3 325 ? 117.853 117.154 143.288 1.00 56.39  ? 315 VAL B CA  1 
ATOM 6288 C C   . VAL C 3 325 ? 118.591 116.520 144.459 1.00 62.01  ? 315 VAL B C   1 
ATOM 6289 O O   . VAL C 3 325 ? 118.227 115.434 144.921 1.00 62.99  ? 315 VAL B O   1 
ATOM 6290 C CB  . VAL C 3 325 ? 116.398 117.471 143.659 1.00 53.99  ? 315 VAL B CB  1 
ATOM 6291 C CG1 . VAL C 3 325 ? 116.346 118.273 144.945 1.00 54.94  ? 315 VAL B CG1 1 
ATOM 6292 C CG2 . VAL C 3 325 ? 115.717 118.225 142.532 1.00 61.39  ? 315 VAL B CG2 1 
ATOM 6293 N N   . SER C 3 326 ? 119.628 117.200 144.946 1.00 55.02  ? 316 SER B N   1 
ATOM 6294 C CA  . SER C 3 326 ? 120.487 116.639 145.978 1.00 46.83  ? 316 SER B CA  1 
ATOM 6295 C C   . SER C 3 326 ? 120.261 117.235 147.360 1.00 50.15  ? 316 SER B C   1 
ATOM 6296 O O   . SER C 3 326 ? 120.700 116.638 148.348 1.00 59.47  ? 316 SER B O   1 
ATOM 6297 C CB  . SER C 3 326 ? 121.960 116.819 145.597 1.00 44.94  ? 316 SER B CB  1 
ATOM 6298 O OG  . SER C 3 326 ? 122.284 118.191 145.468 1.00 41.91  ? 316 SER B OG  1 
ATOM 6299 N N   . CYS C 3 327 ? 119.594 118.382 147.463 1.00 44.07  ? 317 CYS B N   1 
ATOM 6300 C CA  . CYS C 3 327 ? 119.417 119.026 148.754 1.00 37.04  ? 317 CYS B CA  1 
ATOM 6301 C C   . CYS C 3 327 ? 118.173 119.900 148.732 1.00 40.76  ? 317 CYS B C   1 
ATOM 6302 O O   . CYS C 3 327 ? 117.847 120.518 147.716 1.00 48.67  ? 317 CYS B O   1 
ATOM 6303 C CB  . CYS C 3 327 ? 120.642 119.863 149.128 1.00 39.98  ? 317 CYS B CB  1 
ATOM 6304 S SG  . CYS C 3 327 ? 121.249 120.912 147.790 1.00 70.67  ? 317 CYS B SG  1 
ATOM 6305 N N   . LEU C 3 328 ? 117.488 119.947 149.872 1.00 38.65  ? 318 LEU B N   1 
ATOM 6306 C CA  . LEU C 3 328 ? 116.319 120.789 150.063 1.00 28.12  ? 318 LEU B CA  1 
ATOM 6307 C C   . LEU C 3 328 ? 116.534 121.673 151.282 1.00 34.93  ? 318 LEU B C   1 
ATOM 6308 O O   . LEU C 3 328 ? 117.283 121.331 152.199 1.00 50.72  ? 318 LEU B O   1 
ATOM 6309 C CB  . LEU C 3 328 ? 115.037 119.965 150.250 1.00 28.63  ? 318 LEU B CB  1 
ATOM 6310 C CG  . LEU C 3 328 ? 114.326 119.438 149.004 1.00 30.88  ? 318 LEU B CG  1 
ATOM 6311 C CD1 . LEU C 3 328 ? 112.917 118.995 149.349 1.00 34.12  ? 318 LEU B CD1 1 
ATOM 6312 C CD2 . LEU C 3 328 ? 114.304 120.485 147.917 1.00 39.06  ? 318 LEU B CD2 1 
ATOM 6313 N N   . GLY C 3 329 ? 115.861 122.818 151.283 1.00 36.14  ? 319 GLY B N   1 
ATOM 6314 C CA  . GLY C 3 329 ? 115.949 123.729 152.404 1.00 32.04  ? 319 GLY B CA  1 
ATOM 6315 C C   . GLY C 3 329 ? 114.726 124.607 152.546 1.00 36.24  ? 319 GLY B C   1 
ATOM 6316 O O   . GLY C 3 329 ? 114.303 125.257 151.586 1.00 52.50  ? 319 GLY B O   1 
ATOM 6317 N N   . VAL C 3 330 ? 114.150 124.634 153.743 1.00 40.04  ? 320 VAL B N   1 
ATOM 6318 C CA  . VAL C 3 330 ? 112.993 125.464 154.052 1.00 41.31  ? 320 VAL B CA  1 
ATOM 6319 C C   . VAL C 3 330 ? 113.413 126.478 155.104 1.00 47.48  ? 320 VAL B C   1 
ATOM 6320 O O   . VAL C 3 330 ? 113.945 126.103 156.155 1.00 56.40  ? 320 VAL B O   1 
ATOM 6321 C CB  . VAL C 3 330 ? 111.803 124.622 154.544 1.00 40.32  ? 320 VAL B CB  1 
ATOM 6322 C CG1 . VAL C 3 330 ? 110.641 125.520 154.922 1.00 41.72  ? 320 VAL B CG1 1 
ATOM 6323 C CG2 . VAL C 3 330 ? 111.387 123.629 153.475 1.00 46.18  ? 320 VAL B CG2 1 
ATOM 6324 N N   . THR C 3 331 ? 113.178 127.756 154.819 1.00 48.35  ? 321 THR B N   1 
ATOM 6325 C CA  . THR C 3 331 ? 113.597 128.813 155.726 1.00 45.00  ? 321 THR B CA  1 
ATOM 6326 C C   . THR C 3 331 ? 112.869 128.694 157.062 1.00 46.63  ? 321 THR B C   1 
ATOM 6327 O O   . THR C 3 331 ? 111.843 128.021 157.186 1.00 57.72  ? 321 THR B O   1 
ATOM 6328 C CB  . THR C 3 331 ? 113.337 130.185 155.109 1.00 45.52  ? 321 THR B CB  1 
ATOM 6329 O OG1 . THR C 3 331 ? 112.003 130.604 155.419 1.00 54.96  ? 321 THR B OG1 1 
ATOM 6330 C CG2 . THR C 3 331 ? 113.512 130.134 153.602 1.00 46.68  ? 321 THR B CG2 1 
ATOM 6331 N N   . ASP C 3 332 ? 113.425 129.360 158.076 1.00 52.90  ? 322 ASP B N   1 
ATOM 6332 C CA  . ASP C 3 332 ? 112.881 129.240 159.424 1.00 59.15  ? 322 ASP B CA  1 
ATOM 6333 C C   . ASP C 3 332 ? 111.467 129.802 159.508 1.00 62.75  ? 322 ASP B C   1 
ATOM 6334 O O   . ASP C 3 332 ? 110.616 129.250 160.214 1.00 65.31  ? 322 ASP B O   1 
ATOM 6335 C CB  . ASP C 3 332 ? 113.802 129.936 160.423 1.00 60.76  ? 322 ASP B CB  1 
ATOM 6336 C CG  . ASP C 3 332 ? 115.046 129.126 160.725 1.00 62.41  ? 322 ASP B CG  1 
ATOM 6337 O OD1 . ASP C 3 332 ? 115.895 128.980 159.822 1.00 58.83  ? 322 ASP B OD1 1 
ATOM 6338 O OD2 . ASP C 3 332 ? 115.172 128.630 161.865 1.00 68.60  ? 322 ASP B OD2 1 
ATOM 6339 N N   . ASP C 3 333 ? 111.196 130.896 158.798 1.00 64.67  ? 323 ASP B N   1 
ATOM 6340 C CA  . ASP C 3 333 ? 109.853 131.457 158.773 1.00 67.02  ? 323 ASP B CA  1 
ATOM 6341 C C   . ASP C 3 333 ? 108.939 130.765 157.770 1.00 67.60  ? 323 ASP B C   1 
ATOM 6342 O O   . ASP C 3 333 ? 107.744 131.072 157.732 1.00 70.30  ? 323 ASP B O   1 
ATOM 6343 C CB  . ASP C 3 333 ? 109.911 132.957 158.465 1.00 67.96  ? 323 ASP B CB  1 
ATOM 6344 C CG  . ASP C 3 333 ? 110.796 133.278 157.275 1.00 69.19  ? 323 ASP B CG  1 
ATOM 6345 O OD1 . ASP C 3 333 ? 111.086 132.362 156.479 1.00 68.38  ? 323 ASP B OD1 1 
ATOM 6346 O OD2 . ASP C 3 333 ? 111.197 134.451 157.132 1.00 69.79  ? 323 ASP B OD2 1 
ATOM 6347 N N   . GLY C 3 334 ? 109.465 129.843 156.967 1.00 64.23  ? 324 GLY B N   1 
ATOM 6348 C CA  . GLY C 3 334 ? 108.670 129.168 155.963 1.00 59.81  ? 324 GLY B CA  1 
ATOM 6349 C C   . GLY C 3 334 ? 108.406 129.972 154.713 1.00 55.99  ? 324 GLY B C   1 
ATOM 6350 O O   . GLY C 3 334 ? 107.606 129.541 153.877 1.00 61.78  ? 324 GLY B O   1 
ATOM 6351 N N   . MET C 3 335 ? 109.057 131.126 154.554 1.00 52.56  ? 325 MET B N   1 
ATOM 6352 C CA  . MET C 3 335 ? 108.772 132.000 153.424 1.00 62.28  ? 325 MET B CA  1 
ATOM 6353 C C   . MET C 3 335 ? 109.226 131.417 152.092 1.00 62.44  ? 325 MET B C   1 
ATOM 6354 O O   . MET C 3 335 ? 108.713 131.832 151.049 1.00 66.99  ? 325 MET B O   1 
ATOM 6355 C CB  . MET C 3 335 ? 109.431 133.365 153.634 1.00 68.35  ? 325 MET B CB  1 
ATOM 6356 C CG  . MET C 3 335 ? 108.814 134.495 152.817 1.00 68.38  ? 325 MET B CG  1 
ATOM 6357 S SD  . MET C 3 335 ? 107.113 134.882 153.273 1.00 69.53  ? 325 MET B SD  1 
ATOM 6358 C CE  . MET C 3 335 ? 107.254 134.978 155.055 1.00 59.04  ? 325 MET B CE  1 
ATOM 6359 N N   . ALA C 3 336 ? 110.168 130.476 152.089 1.00 48.78  ? 326 ALA B N   1 
ATOM 6360 C CA  . ALA C 3 336 ? 110.705 129.990 150.828 1.00 49.57  ? 326 ALA B CA  1 
ATOM 6361 C C   . ALA C 3 336 ? 111.205 128.562 150.976 1.00 48.54  ? 326 ALA B C   1 
ATOM 6362 O O   . ALA C 3 336 ? 111.471 128.081 152.080 1.00 51.23  ? 326 ALA B O   1 
ATOM 6363 C CB  . ALA C 3 336 ? 111.836 130.889 150.318 1.00 49.14  ? 326 ALA B CB  1 
ATOM 6364 N N   . VAL C 3 337 ? 111.320 127.889 149.834 1.00 46.60  ? 327 VAL B N   1 
ATOM 6365 C CA  . VAL C 3 337 ? 111.935 126.572 149.727 1.00 42.23  ? 327 VAL B CA  1 
ATOM 6366 C C   . VAL C 3 337 ? 112.983 126.654 148.631 1.00 42.64  ? 327 VAL B C   1 
ATOM 6367 O O   . VAL C 3 337 ? 112.670 127.039 147.499 1.00 55.66  ? 327 VAL B O   1 
ATOM 6368 C CB  . VAL C 3 337 ? 110.909 125.474 149.407 1.00 38.86  ? 327 VAL B CB  1 
ATOM 6369 C CG1 . VAL C 3 337 ? 111.610 124.148 149.172 1.00 39.08  ? 327 VAL B CG1 1 
ATOM 6370 C CG2 . VAL C 3 337 ? 109.897 125.353 150.527 1.00 49.56  ? 327 VAL B CG2 1 
ATOM 6371 N N   . ALA C 3 338 ? 114.219 126.295 148.957 1.00 22.40  ? 328 ALA B N   1 
ATOM 6372 C CA  . ALA C 3 338 ? 115.324 126.364 148.013 1.00 24.66  ? 328 ALA B CA  1 
ATOM 6373 C C   . ALA C 3 338 ? 115.824 124.960 147.713 1.00 26.33  ? 328 ALA B C   1 
ATOM 6374 O O   . ALA C 3 338 ? 116.031 124.160 148.631 1.00 33.64  ? 328 ALA B O   1 
ATOM 6375 C CB  . ALA C 3 338 ? 116.458 127.231 148.557 1.00 28.26  ? 328 ALA B CB  1 
ATOM 6376 N N   . THR C 3 339 ? 116.009 124.665 146.431 1.00 48.98  ? 329 THR B N   1 
ATOM 6377 C CA  . THR C 3 339 ? 116.420 123.349 145.968 1.00 46.84  ? 329 THR B CA  1 
ATOM 6378 C C   . THR C 3 339 ? 117.750 123.453 145.239 1.00 42.92  ? 329 THR B C   1 
ATOM 6379 O O   . THR C 3 339 ? 117.964 124.375 144.446 1.00 50.23  ? 329 THR B O   1 
ATOM 6380 C CB  . THR C 3 339 ? 115.374 122.735 145.032 1.00 49.15  ? 329 THR B CB  1 
ATOM 6381 O OG1 . THR C 3 339 ? 115.546 123.268 143.715 1.00 58.48  ? 329 THR B OG1 1 
ATOM 6382 C CG2 . THR C 3 339 ? 113.970 123.056 145.510 1.00 45.47  ? 329 THR B CG2 1 
ATOM 6383 N N   . GLY C 3 340 ? 118.637 122.510 145.509 1.00 42.97  ? 330 GLY B N   1 
ATOM 6384 C CA  . GLY C 3 340 ? 119.911 122.418 144.813 1.00 43.72  ? 330 GLY B CA  1 
ATOM 6385 C C   . GLY C 3 340 ? 120.027 121.071 144.129 1.00 49.21  ? 330 GLY B C   1 
ATOM 6386 O O   . GLY C 3 340 ? 119.581 120.057 144.666 1.00 58.53  ? 330 GLY B O   1 
ATOM 6387 N N   . SER C 3 341 ? 120.625 121.068 142.942 1.00 60.41  ? 331 SER B N   1 
ATOM 6388 C CA  . SER C 3 341 ? 120.700 119.860 142.133 1.00 64.66  ? 331 SER B CA  1 
ATOM 6389 C C   . SER C 3 341 ? 122.104 119.744 141.555 1.00 63.48  ? 331 SER B C   1 
ATOM 6390 O O   . SER C 3 341 ? 122.995 120.539 141.866 1.00 66.30  ? 331 SER B O   1 
ATOM 6391 C CB  . SER C 3 341 ? 119.622 119.872 141.042 1.00 70.13  ? 331 SER B CB  1 
ATOM 6392 O OG  . SER C 3 341 ? 118.327 119.933 141.609 1.00 71.84  ? 331 SER B OG  1 
ATOM 6393 N N   . TRP C 3 342 ? 122.296 118.741 140.703 1.00 65.66  ? 332 TRP B N   1 
ATOM 6394 C CA  . TRP C 3 342 ? 123.603 118.445 140.132 1.00 67.86  ? 332 TRP B CA  1 
ATOM 6395 C C   . TRP C 3 342 ? 123.929 119.287 138.906 1.00 70.95  ? 332 TRP B C   1 
ATOM 6396 O O   . TRP C 3 342 ? 125.042 119.174 138.380 1.00 71.39  ? 332 TRP B O   1 
ATOM 6397 C CB  . TRP C 3 342 ? 123.694 116.958 139.777 1.00 70.81  ? 332 TRP B CB  1 
ATOM 6398 C CG  . TRP C 3 342 ? 123.981 116.078 140.957 1.00 69.43  ? 332 TRP B CG  1 
ATOM 6399 C CD1 . TRP C 3 342 ? 124.320 116.480 142.214 1.00 72.10  ? 332 TRP B CD1 1 
ATOM 6400 C CD2 . TRP C 3 342 ? 123.964 114.646 140.985 1.00 69.56  ? 332 TRP B CD2 1 
ATOM 6401 N NE1 . TRP C 3 342 ? 124.510 115.389 143.026 1.00 66.56  ? 332 TRP B NE1 1 
ATOM 6402 C CE2 . TRP C 3 342 ? 124.298 114.251 142.294 1.00 69.91  ? 332 TRP B CE2 1 
ATOM 6403 C CE3 . TRP C 3 342 ? 123.697 113.660 140.031 1.00 72.50  ? 332 TRP B CE3 1 
ATOM 6404 C CZ2 . TRP C 3 342 ? 124.373 112.913 142.674 1.00 73.32  ? 332 TRP B CZ2 1 
ATOM 6405 C CZ3 . TRP C 3 342 ? 123.771 112.333 140.410 1.00 70.37  ? 332 TRP B CZ3 1 
ATOM 6406 C CH2 . TRP C 3 342 ? 124.106 111.972 141.719 1.00 70.83  ? 332 TRP B CH2 1 
ATOM 6407 N N   . ASP C 3 343 ? 123.002 120.120 138.433 1.00 76.60  ? 333 ASP B N   1 
ATOM 6408 C CA  . ASP C 3 343 ? 123.264 121.007 137.308 1.00 77.48  ? 333 ASP B CA  1 
ATOM 6409 C C   . ASP C 3 343 ? 123.838 122.349 137.745 1.00 74.85  ? 333 ASP B C   1 
ATOM 6410 O O   . ASP C 3 343 ? 123.805 123.309 136.968 1.00 72.84  ? 333 ASP B O   1 
ATOM 6411 C CB  . ASP C 3 343 ? 121.990 121.219 136.487 1.00 77.03  ? 333 ASP B CB  1 
ATOM 6412 C CG  . ASP C 3 343 ? 120.773 121.453 137.351 1.00 75.21  ? 333 ASP B CG  1 
ATOM 6413 O OD1 . ASP C 3 343 ? 120.881 121.282 138.580 1.00 73.41  ? 333 ASP B OD1 1 
ATOM 6414 O OD2 . ASP C 3 343 ? 119.709 121.808 136.802 1.00 82.54  ? 333 ASP B OD2 1 
ATOM 6415 N N   . SER C 3 344 ? 124.379 122.427 138.964 1.00 75.03  ? 334 SER B N   1 
ATOM 6416 C CA  . SER C 3 344 ? 125.015 123.636 139.499 1.00 76.88  ? 334 SER B CA  1 
ATOM 6417 C C   . SER C 3 344 ? 124.074 124.839 139.471 1.00 70.06  ? 334 SER B C   1 
ATOM 6418 O O   . SER C 3 344 ? 124.484 125.961 139.170 1.00 71.32  ? 334 SER B O   1 
ATOM 6419 C CB  . SER C 3 344 ? 126.325 123.962 138.771 1.00 75.83  ? 334 SER B CB  1 
ATOM 6420 O OG  . SER C 3 344 ? 126.260 123.712 137.378 1.00 73.30  ? 334 SER B OG  1 
ATOM 6421 N N   . PHE C 3 345 ? 122.802 124.611 139.795 1.00 64.28  ? 335 PHE B N   1 
ATOM 6422 C CA  . PHE C 3 345 ? 121.832 125.695 139.883 1.00 69.30  ? 335 PHE B CA  1 
ATOM 6423 C C   . PHE C 3 345 ? 120.968 125.508 141.120 1.00 66.82  ? 335 PHE B C   1 
ATOM 6424 O O   . PHE C 3 345 ? 120.475 124.407 141.375 1.00 70.80  ? 335 PHE B O   1 
ATOM 6425 C CB  . PHE C 3 345 ? 120.948 125.764 138.631 1.00 68.58  ? 335 PHE B CB  1 
ATOM 6426 C CG  . PHE C 3 345 ? 121.688 126.164 137.387 1.00 70.84  ? 335 PHE B CG  1 
ATOM 6427 C CD1 . PHE C 3 345 ? 122.394 127.353 137.337 1.00 72.45  ? 335 PHE B CD1 1 
ATOM 6428 C CD2 . PHE C 3 345 ? 121.664 125.359 136.262 1.00 70.53  ? 335 PHE B CD2 1 
ATOM 6429 C CE1 . PHE C 3 345 ? 123.075 127.724 136.194 1.00 67.96  ? 335 PHE B CE1 1 
ATOM 6430 C CE2 . PHE C 3 345 ? 122.343 125.724 135.116 1.00 73.63  ? 335 PHE B CE2 1 
ATOM 6431 C CZ  . PHE C 3 345 ? 123.048 126.909 135.083 1.00 69.86  ? 335 PHE B CZ  1 
ATOM 6432 N N   . LEU C 3 346 ? 120.790 126.585 141.879 1.00 52.73  ? 336 LEU B N   1 
ATOM 6433 C CA  . LEU C 3 346 ? 119.890 126.615 143.023 1.00 53.46  ? 336 LEU B CA  1 
ATOM 6434 C C   . LEU C 3 346 ? 118.668 127.445 142.660 1.00 51.73  ? 336 LEU B C   1 
ATOM 6435 O O   . LEU C 3 346 ? 118.803 128.545 142.116 1.00 62.32  ? 336 LEU B O   1 
ATOM 6436 C CB  . LEU C 3 346 ? 120.575 127.206 144.257 1.00 57.07  ? 336 LEU B CB  1 
ATOM 6437 C CG  . LEU C 3 346 ? 121.691 126.400 144.920 1.00 57.52  ? 336 LEU B CG  1 
ATOM 6438 C CD1 . LEU C 3 346 ? 123.043 126.909 144.463 1.00 62.98  ? 336 LEU B CD1 1 
ATOM 6439 C CD2 . LEU C 3 346 ? 121.575 126.470 146.432 1.00 49.50  ? 336 LEU B CD2 1 
ATOM 6440 N N   . LYS C 3 347 ? 117.484 126.920 142.955 1.00 41.03  ? 337 LYS B N   1 
ATOM 6441 C CA  . LYS C 3 347 ? 116.233 127.601 142.656 1.00 51.13  ? 337 LYS B CA  1 
ATOM 6442 C C   . LYS C 3 347 ? 115.430 127.776 143.934 1.00 53.04  ? 337 LYS B C   1 
ATOM 6443 O O   . LYS C 3 347 ? 115.268 126.826 144.707 1.00 60.14  ? 337 LYS B O   1 
ATOM 6444 C CB  . LYS C 3 347 ? 115.420 126.831 141.612 1.00 58.32  ? 337 LYS B CB  1 
ATOM 6445 C CG  . LYS C 3 347 ? 115.899 127.060 140.190 1.00 59.93  ? 337 LYS B CG  1 
ATOM 6446 C CD  . LYS C 3 347 ? 115.125 126.225 139.189 1.00 61.56  ? 337 LYS B CD  1 
ATOM 6447 C CE  . LYS C 3 347 ? 115.731 126.353 137.801 1.00 59.76  ? 337 LYS B CE  1 
ATOM 6448 N NZ  . LYS C 3 347 ? 115.054 125.477 136.810 1.00 55.55  ? 337 LYS B NZ  1 
ATOM 6449 N N   . ILE C 3 348 ? 114.929 128.988 144.149 1.00 53.68  ? 338 ILE B N   1 
ATOM 6450 C CA  . ILE C 3 348 ? 114.161 129.334 145.337 1.00 44.77  ? 338 ILE B CA  1 
ATOM 6451 C C   . ILE C 3 348 ? 112.691 129.407 144.954 1.00 49.93  ? 338 ILE B C   1 
ATOM 6452 O O   . ILE C 3 348 ? 112.328 130.082 143.983 1.00 58.20  ? 338 ILE B O   1 
ATOM 6453 C CB  . ILE C 3 348 ? 114.645 130.662 145.939 1.00 46.47  ? 338 ILE B CB  1 
ATOM 6454 C CG1 . ILE C 3 348 ? 116.174 130.687 145.967 1.00 49.25  ? 338 ILE B CG1 1 
ATOM 6455 C CG2 . ILE C 3 348 ? 114.073 130.855 147.332 1.00 50.30  ? 338 ILE B CG2 1 
ATOM 6456 C CD1 . ILE C 3 348 ? 116.753 131.873 146.683 1.00 55.25  ? 338 ILE B CD1 1 
ATOM 6457 N N   . TRP C 3 349 ? 111.847 128.715 145.711 1.00 57.68  ? 339 TRP B N   1 
ATOM 6458 C CA  . TRP C 3 349 ? 110.438 128.575 145.385 1.00 58.69  ? 339 TRP B CA  1 
ATOM 6459 C C   . TRP C 3 349 ? 109.578 129.196 146.475 1.00 58.76  ? 339 TRP B C   1 
ATOM 6460 O O   . TRP C 3 349 ? 109.956 129.224 147.649 1.00 67.54  ? 339 TRP B O   1 
ATOM 6461 C CB  . TRP C 3 349 ? 110.064 127.100 145.196 1.00 55.40  ? 339 TRP B CB  1 
ATOM 6462 C CG  . TRP C 3 349 ? 110.980 126.377 144.258 1.00 61.23  ? 339 TRP B CG  1 
ATOM 6463 C CD1 . TRP C 3 349 ? 112.262 125.981 144.505 1.00 60.78  ? 339 TRP B CD1 1 
ATOM 6464 C CD2 . TRP C 3 349 ? 110.687 125.970 142.918 1.00 66.45  ? 339 TRP B CD2 1 
ATOM 6465 N NE1 . TRP C 3 349 ? 112.784 125.352 143.403 1.00 62.11  ? 339 TRP B NE1 1 
ATOM 6466 C CE2 . TRP C 3 349 ? 111.837 125.332 142.414 1.00 65.23  ? 339 TRP B CE2 1 
ATOM 6467 C CE3 . TRP C 3 349 ? 109.563 126.082 142.095 1.00 65.96  ? 339 TRP B CE3 1 
ATOM 6468 C CZ2 . TRP C 3 349 ? 111.895 124.809 141.127 1.00 61.16  ? 339 TRP B CZ2 1 
ATOM 6469 C CZ3 . TRP C 3 349 ? 109.623 125.563 140.818 1.00 66.95  ? 339 TRP B CZ3 1 
ATOM 6470 C CH2 . TRP C 3 349 ? 110.780 124.934 140.346 1.00 66.07  ? 339 TRP B CH2 1 
ATOM 6471 N N   . ASN C 3 350 ? 108.416 129.697 146.071 1.00 67.54  ? 340 ASN B N   1 
ATOM 6472 C CA  . ASN C 3 350 ? 107.478 130.316 146.999 1.00 73.08  ? 340 ASN B CA  1 
ATOM 6473 C C   . ASN C 3 350 ? 106.053 130.224 146.466 1.00 79.52  ? 340 ASN B C   1 
ATOM 6474 O O   . ASN C 3 350 ? 105.118 129.912 147.203 1.00 79.97  ? 340 ASN B O   1 
ATOM 6475 C CB  . ASN C 3 350 ? 107.856 131.776 147.248 1.00 73.98  ? 340 ASN B CB  1 
ATOM 6476 C CG  . ASN C 3 350 ? 107.251 132.326 148.524 1.00 75.84  ? 340 ASN B CG  1 
ATOM 6477 O OD1 . ASN C 3 350 ? 106.320 131.748 149.083 1.00 73.35  ? 340 ASN B OD1 1 
ATOM 6478 N ND2 . ASN C 3 350 ? 107.784 133.446 148.995 1.00 73.45  ? 340 ASN B ND2 1 
ATOM 6479 O OXT . ASN C 3 350 ? 105.803 130.456 145.283 1.00 76.70  ? 340 ASN B OXT 1 
ATOM 6480 N N   . ILE D 4 9   ? 131.523 86.233  171.226 1.00 125.56 ? 9   ILE G N   1 
ATOM 6481 C CA  . ILE D 4 9   ? 130.800 86.009  172.471 1.00 127.94 ? 9   ILE G CA  1 
ATOM 6482 C C   . ILE D 4 9   ? 130.741 87.304  173.279 1.00 128.31 ? 9   ILE G C   1 
ATOM 6483 O O   . ILE D 4 9   ? 129.803 87.529  174.044 1.00 126.79 ? 9   ILE G O   1 
ATOM 6484 C CB  . ILE D 4 9   ? 131.440 84.860  173.284 1.00 127.55 ? 9   ILE G CB  1 
ATOM 6485 C CG1 . ILE D 4 9   ? 130.598 84.534  174.520 1.00 127.59 ? 9   ILE G CG1 1 
ATOM 6486 C CG2 . ILE D 4 9   ? 132.874 85.199  173.671 1.00 125.90 ? 9   ILE G CG2 1 
ATOM 6487 C CD1 . ILE D 4 9   ? 129.230 83.974  174.199 1.00 126.47 ? 9   ILE G CD1 1 
ATOM 6488 N N   . ALA D 4 10  ? 131.742 88.162  173.094 1.00 128.99 ? 10  ALA G N   1 
ATOM 6489 C CA  . ALA D 4 10  ? 131.800 89.446  173.778 1.00 128.91 ? 10  ALA G CA  1 
ATOM 6490 C C   . ALA D 4 10  ? 131.215 90.586  172.954 1.00 128.79 ? 10  ALA G C   1 
ATOM 6491 O O   . ALA D 4 10  ? 131.190 91.725  173.430 1.00 128.87 ? 10  ALA G O   1 
ATOM 6492 C CB  . ALA D 4 10  ? 133.247 89.777  174.158 1.00 127.54 ? 10  ALA G CB  1 
ATOM 6493 N N   . GLN D 4 11  ? 130.747 90.310  171.737 1.00 126.28 ? 11  GLN G N   1 
ATOM 6494 C CA  . GLN D 4 11  ? 130.183 91.339  170.873 1.00 125.49 ? 11  GLN G CA  1 
ATOM 6495 C C   . GLN D 4 11  ? 128.669 91.445  170.969 1.00 126.32 ? 11  GLN G C   1 
ATOM 6496 O O   . GLN D 4 11  ? 128.126 92.542  170.804 1.00 125.76 ? 11  GLN G O   1 
ATOM 6497 C CB  . GLN D 4 11  ? 130.575 91.080  169.414 1.00 124.65 ? 11  GLN G CB  1 
ATOM 6498 N N   . ALA D 4 12  ? 127.976 90.338  171.228 1.00 125.62 ? 12  ALA G N   1 
ATOM 6499 C CA  . ALA D 4 12  ? 126.523 90.335  171.324 1.00 124.96 ? 12  ALA G CA  1 
ATOM 6500 C C   . ALA D 4 12  ? 126.016 90.632  172.730 1.00 125.16 ? 12  ALA G C   1 
ATOM 6501 O O   . ALA D 4 12  ? 124.799 90.691  172.932 1.00 123.94 ? 12  ALA G O   1 
ATOM 6502 C CB  . ALA D 4 12  ? 125.967 88.987  170.853 1.00 123.06 ? 12  ALA G CB  1 
ATOM 6503 N N   . ARG D 4 13  ? 126.913 90.817  173.701 1.00 130.22 ? 13  ARG G N   1 
ATOM 6504 C CA  . ARG D 4 13  ? 126.478 91.091  175.067 1.00 130.41 ? 13  ARG G CA  1 
ATOM 6505 C C   . ARG D 4 13  ? 125.827 92.465  175.179 1.00 130.83 ? 13  ARG G C   1 
ATOM 6506 O O   . ARG D 4 13  ? 124.869 92.644  175.939 1.00 128.66 ? 13  ARG G O   1 
ATOM 6507 C CB  . ARG D 4 13  ? 127.662 90.978  176.027 1.00 128.16 ? 13  ARG G CB  1 
ATOM 6508 N N   . LYS D 4 14  ? 126.340 93.450  174.442 1.00 130.36 ? 14  LYS G N   1 
ATOM 6509 C CA  . LYS D 4 14  ? 125.777 94.795  174.494 1.00 129.55 ? 14  LYS G CA  1 
ATOM 6510 C C   . LYS D 4 14  ? 124.470 94.905  173.718 1.00 129.41 ? 14  LYS G C   1 
ATOM 6511 O O   . LYS D 4 14  ? 123.637 95.763  174.035 1.00 127.59 ? 14  LYS G O   1 
ATOM 6512 C CB  . LYS D 4 14  ? 126.797 95.804  173.965 1.00 128.40 ? 14  LYS G CB  1 
ATOM 6513 C CG  . LYS D 4 14  ? 127.345 95.465  172.590 1.00 126.24 ? 14  LYS G CG  1 
ATOM 6514 C CD  . LYS D 4 14  ? 128.552 96.321  172.249 1.00 127.37 ? 14  LYS G CD  1 
ATOM 6515 C CE  . LYS D 4 14  ? 128.983 96.111  170.808 1.00 128.52 ? 14  LYS G CE  1 
ATOM 6516 N NZ  . LYS D 4 14  ? 129.430 94.713  170.565 1.00 126.44 ? 14  LYS G NZ  1 
ATOM 6517 N N   . LEU D 4 15  ? 124.276 94.060  172.702 1.00 129.97 ? 15  LEU G N   1 
ATOM 6518 C CA  . LEU D 4 15  ? 123.062 94.134  171.894 1.00 130.04 ? 15  LEU G CA  1 
ATOM 6519 C C   . LEU D 4 15  ? 121.822 93.808  172.719 1.00 128.93 ? 15  LEU G C   1 
ATOM 6520 O O   . LEU D 4 15  ? 120.797 94.494  172.614 1.00 128.92 ? 15  LEU G O   1 
ATOM 6521 C CB  . LEU D 4 15  ? 123.178 93.189  170.699 1.00 129.74 ? 15  LEU G CB  1 
ATOM 6522 C CG  . LEU D 4 15  ? 122.227 93.437  169.528 1.00 129.92 ? 15  LEU G CG  1 
ATOM 6523 C CD1 . LEU D 4 15  ? 122.997 93.477  168.218 1.00 128.54 ? 15  LEU G CD1 1 
ATOM 6524 C CD2 . LEU D 4 15  ? 121.142 92.374  169.484 1.00 128.16 ? 15  LEU G CD2 1 
ATOM 6525 N N   . VAL D 4 16  ? 121.894 92.766  173.549 1.00 128.28 ? 16  VAL G N   1 
ATOM 6526 C CA  . VAL D 4 16  ? 120.740 92.398  174.362 1.00 130.15 ? 16  VAL G CA  1 
ATOM 6527 C C   . VAL D 4 16  ? 120.462 93.465  175.415 1.00 131.24 ? 16  VAL G C   1 
ATOM 6528 O O   . VAL D 4 16  ? 119.304 93.729  175.753 1.00 130.94 ? 16  VAL G O   1 
ATOM 6529 C CB  . VAL D 4 16  ? 120.938 91.005  174.988 1.00 129.72 ? 16  VAL G CB  1 
ATOM 6530 C CG1 . VAL D 4 16  ? 120.903 89.934  173.907 1.00 129.11 ? 16  VAL G CG1 1 
ATOM 6531 C CG2 . VAL D 4 16  ? 122.242 90.940  175.759 1.00 128.58 ? 16  VAL G CG2 1 
ATOM 6532 N N   . GLU D 4 17  ? 121.511 94.092  175.952 1.00 128.13 ? 17  GLU G N   1 
ATOM 6533 C CA  . GLU D 4 17  ? 121.308 95.200  176.882 1.00 126.57 ? 17  GLU G CA  1 
ATOM 6534 C C   . GLU D 4 17  ? 120.631 96.379  176.193 1.00 125.45 ? 17  GLU G C   1 
ATOM 6535 O O   . GLU D 4 17  ? 119.754 97.032  176.774 1.00 124.67 ? 17  GLU G O   1 
ATOM 6536 C CB  . GLU D 4 17  ? 122.644 95.627  177.491 1.00 126.60 ? 17  GLU G CB  1 
ATOM 6537 N N   . GLN D 4 18  ? 121.028 96.668  174.951 1.00 123.29 ? 18  GLN G N   1 
ATOM 6538 C CA  . GLN D 4 18  ? 120.339 97.694  174.176 1.00 123.77 ? 18  GLN G CA  1 
ATOM 6539 C C   . GLN D 4 18  ? 118.873 97.334  173.978 1.00 123.31 ? 18  GLN G C   1 
ATOM 6540 O O   . GLN D 4 18  ? 117.998 98.207  174.023 1.00 125.87 ? 18  GLN G O   1 
ATOM 6541 C CB  . GLN D 4 18  ? 121.025 97.888  172.824 1.00 123.82 ? 18  GLN G CB  1 
ATOM 6542 C CG  . GLN D 4 18  ? 122.192 98.858  172.839 1.00 125.47 ? 18  GLN G CG  1 
ATOM 6543 C CD  . GLN D 4 18  ? 122.661 99.216  171.442 1.00 126.40 ? 18  GLN G CD  1 
ATOM 6544 O OE1 . GLN D 4 18  ? 122.802 98.348  170.581 1.00 124.23 ? 18  GLN G OE1 1 
ATOM 6545 N NE2 . GLN D 4 18  ? 122.903 100.501 171.210 1.00 124.31 ? 18  GLN G NE2 1 
ATOM 6546 N N   . LEU D 4 19  ? 118.588 96.053  173.741 1.00 116.83 ? 19  LEU G N   1 
ATOM 6547 C CA  . LEU D 4 19  ? 117.200 95.624  173.591 1.00 116.43 ? 19  LEU G CA  1 
ATOM 6548 C C   . LEU D 4 19  ? 116.419 95.793  174.891 1.00 118.62 ? 19  LEU G C   1 
ATOM 6549 O O   . LEU D 4 19  ? 115.243 96.172  174.865 1.00 119.97 ? 19  LEU G O   1 
ATOM 6550 C CB  . LEU D 4 19  ? 117.144 94.180  173.102 1.00 118.44 ? 19  LEU G CB  1 
ATOM 6551 C CG  . LEU D 4 19  ? 117.757 93.955  171.719 1.00 122.07 ? 19  LEU G CG  1 
ATOM 6552 C CD1 . LEU D 4 19  ? 117.645 92.499  171.307 1.00 122.45 ? 19  LEU G CD1 1 
ATOM 6553 C CD2 . LEU D 4 19  ? 117.104 94.863  170.690 1.00 119.64 ? 19  LEU G CD2 1 
ATOM 6554 N N   . LYS D 4 20  ? 117.049 95.508  176.036 1.00 116.53 ? 20  LYS G N   1 
ATOM 6555 C CA  . LYS D 4 20  ? 116.405 95.798  177.318 1.00 116.27 ? 20  LYS G CA  1 
ATOM 6556 C C   . LYS D 4 20  ? 116.099 97.282  177.454 1.00 115.28 ? 20  LYS G C   1 
ATOM 6557 O O   . LYS D 4 20  ? 115.010 97.662  177.900 1.00 111.51 ? 20  LYS G O   1 
ATOM 6558 C CB  . LYS D 4 20  ? 117.277 95.349  178.496 1.00 115.66 ? 20  LYS G CB  1 
ATOM 6559 C CG  . LYS D 4 20  ? 117.888 93.968  178.408 1.00 116.07 ? 20  LYS G CG  1 
ATOM 6560 C CD  . LYS D 4 20  ? 116.860 92.936  178.004 1.00 115.66 ? 20  LYS G CD  1 
ATOM 6561 C CE  . LYS D 4 20  ? 117.025 91.649  178.795 1.00 116.04 ? 20  LYS G CE  1 
ATOM 6562 N NZ  . LYS D 4 20  ? 118.391 91.077  178.640 1.00 116.75 ? 20  LYS G NZ  1 
ATOM 6563 N N   . MET D 4 21  ? 117.054 98.135  177.081 1.00 109.27 ? 21  MET G N   1 
ATOM 6564 C CA  . MET D 4 21  ? 116.842 99.575  177.190 1.00 107.27 ? 21  MET G CA  1 
ATOM 6565 C C   . MET D 4 21  ? 115.702 100.036 176.289 1.00 105.47 ? 21  MET G C   1 
ATOM 6566 O O   . MET D 4 21  ? 114.887 100.877 176.686 1.00 106.70 ? 21  MET G O   1 
ATOM 6567 C CB  . MET D 4 21  ? 118.131 100.322 176.851 1.00 104.81 ? 21  MET G CB  1 
ATOM 6568 N N   . GLU D 4 22  ? 115.630 99.496  175.073 1.00 95.85  ? 22  GLU G N   1 
ATOM 6569 C CA  . GLU D 4 22  ? 114.611 99.917  174.117 1.00 96.57  ? 22  GLU G CA  1 
ATOM 6570 C C   . GLU D 4 22  ? 113.234 99.352  174.443 1.00 98.73  ? 22  GLU G C   1 
ATOM 6571 O O   . GLU D 4 22  ? 112.221 99.974  174.104 1.00 97.77  ? 22  GLU G O   1 
ATOM 6572 C CB  . GLU D 4 22  ? 115.016 99.500  172.703 1.00 96.66  ? 22  GLU G CB  1 
ATOM 6573 C CG  . GLU D 4 22  ? 115.872 100.517 171.974 1.00 95.07  ? 22  GLU G CG  1 
ATOM 6574 C CD  . GLU D 4 22  ? 116.334 100.016 170.622 1.00 94.52  ? 22  GLU G CD  1 
ATOM 6575 O OE1 . GLU D 4 22  ? 115.707 99.075  170.092 1.00 94.71  ? 22  GLU G OE1 1 
ATOM 6576 O OE2 . GLU D 4 22  ? 117.323 100.560 170.090 1.00 94.62  ? 22  GLU G OE2 1 
ATOM 6577 N N   . ALA D 4 23  ? 113.171 98.180  175.080 1.00 108.56 ? 23  ALA G N   1 
ATOM 6578 C CA  . ALA D 4 23  ? 111.883 97.542  175.329 1.00 108.94 ? 23  ALA G CA  1 
ATOM 6579 C C   . ALA D 4 23  ? 111.064 98.309  176.360 1.00 109.85 ? 23  ALA G C   1 
ATOM 6580 O O   . ALA D 4 23  ? 109.844 98.447  176.213 1.00 106.91 ? 23  ALA G O   1 
ATOM 6581 C CB  . ALA D 4 23  ? 112.093 96.097  175.779 1.00 107.58 ? 23  ALA G CB  1 
ATOM 6582 N N   . ASN D 4 24  ? 111.714 98.815  177.409 1.00 109.76 ? 24  ASN G N   1 
ATOM 6583 C CA  . ASN D 4 24  ? 111.016 99.499  178.498 1.00 107.64 ? 24  ASN G CA  1 
ATOM 6584 C C   . ASN D 4 24  ? 110.925 100.986 178.169 1.00 104.73 ? 24  ASN G C   1 
ATOM 6585 O O   . ASN D 4 24  ? 111.735 101.809 178.599 1.00 102.37 ? 24  ASN G O   1 
ATOM 6586 C CB  . ASN D 4 24  ? 111.723 99.254  179.825 1.00 108.17 ? 24  ASN G CB  1 
ATOM 6587 C CG  . ASN D 4 24  ? 110.885 99.671  181.018 1.00 107.93 ? 24  ASN G CG  1 
ATOM 6588 O OD1 . ASN D 4 24  ? 109.713 100.022 180.875 1.00 107.84 ? 24  ASN G OD1 1 
ATOM 6589 N ND2 . ASN D 4 24  ? 111.481 99.635  182.203 1.00 106.70 ? 24  ASN G ND2 1 
ATOM 6590 N N   . ILE D 4 25  ? 109.910 101.326 177.379 1.00 107.63 ? 25  ILE G N   1 
ATOM 6591 C CA  . ILE D 4 25  ? 109.615 102.703 177.002 1.00 108.76 ? 25  ILE G CA  1 
ATOM 6592 C C   . ILE D 4 25  ? 108.130 102.945 177.230 1.00 108.77 ? 25  ILE G C   1 
ATOM 6593 O O   . ILE D 4 25  ? 107.299 102.106 176.867 1.00 108.46 ? 25  ILE G O   1 
ATOM 6594 C CB  . ILE D 4 25  ? 109.997 102.992 175.537 1.00 110.16 ? 25  ILE G CB  1 
ATOM 6595 C CG1 . ILE D 4 25  ? 111.509 102.864 175.342 1.00 110.25 ? 25  ILE G CG1 1 
ATOM 6596 C CG2 . ILE D 4 25  ? 109.525 104.376 175.118 1.00 107.28 ? 25  ILE G CG2 1 
ATOM 6597 C CD1 . ILE D 4 25  ? 112.307 103.957 176.016 1.00 109.24 ? 25  ILE G CD1 1 
ATOM 6598 N N   . ASP D 4 26  ? 107.798 104.088 177.830 1.00 114.04 ? 26  ASP G N   1 
ATOM 6599 C CA  . ASP D 4 26  ? 106.404 104.417 178.100 1.00 114.88 ? 26  ASP G CA  1 
ATOM 6600 C C   . ASP D 4 26  ? 105.681 104.743 176.800 1.00 115.24 ? 26  ASP G C   1 
ATOM 6601 O O   . ASP D 4 26  ? 105.709 105.886 176.332 1.00 115.34 ? 26  ASP G O   1 
ATOM 6602 C CB  . ASP D 4 26  ? 106.308 105.590 179.078 1.00 113.03 ? 26  ASP G CB  1 
ATOM 6603 N N   . ARG D 4 27  ? 105.031 103.743 176.214 1.00 104.77 ? 27  ARG G N   1 
ATOM 6604 C CA  . ARG D 4 27  ? 104.383 103.909 174.923 1.00 104.49 ? 27  ARG G CA  1 
ATOM 6605 C C   . ARG D 4 27  ? 103.001 104.533 175.074 1.00 104.72 ? 27  ARG G C   1 
ATOM 6606 O O   . ARG D 4 27  ? 102.340 104.402 176.108 1.00 104.55 ? 27  ARG G O   1 
ATOM 6607 C CB  . ARG D 4 27  ? 104.282 102.566 174.201 1.00 102.83 ? 27  ARG G CB  1 
ATOM 6608 C CG  . ARG D 4 27  ? 105.628 102.039 173.749 1.00 102.22 ? 27  ARG G CG  1 
ATOM 6609 C CD  . ARG D 4 27  ? 105.533 100.696 173.051 1.00 103.66 ? 27  ARG G CD  1 
ATOM 6610 N NE  . ARG D 4 27  ? 106.829 100.288 172.521 1.00 103.74 ? 27  ARG G NE  1 
ATOM 6611 C CZ  . ARG D 4 27  ? 107.747 99.621  173.205 1.00 102.63 ? 27  ARG G CZ  1 
ATOM 6612 N NH1 . ARG D 4 27  ? 107.545 99.256  174.460 1.00 104.24 ? 27  ARG G NH1 1 
ATOM 6613 N NH2 . ARG D 4 27  ? 108.900 99.317  172.617 1.00 102.20 ? 27  ARG G NH2 1 
ATOM 6614 N N   . ILE D 4 28  ? 102.571 105.220 174.019 1.00 103.09 ? 28  ILE G N   1 
ATOM 6615 C CA  . ILE D 4 28  ? 101.301 105.933 173.988 1.00 104.49 ? 28  ILE G CA  1 
ATOM 6616 C C   . ILE D 4 28  ? 100.541 105.502 172.742 1.00 103.94 ? 28  ILE G C   1 
ATOM 6617 O O   . ILE D 4 28  ? 101.139 105.308 171.678 1.00 102.39 ? 28  ILE G O   1 
ATOM 6618 C CB  . ILE D 4 28  ? 101.517 107.463 174.016 1.00 105.77 ? 28  ILE G CB  1 
ATOM 6619 C CG1 . ILE D 4 28  ? 101.716 107.944 175.455 1.00 106.93 ? 28  ILE G CG1 1 
ATOM 6620 C CG2 . ILE D 4 28  ? 100.360 108.204 173.360 1.00 102.77 ? 28  ILE G CG2 1 
ATOM 6621 C CD1 . ILE D 4 28  ? 100.589 107.561 176.389 1.00 105.06 ? 28  ILE G CD1 1 
ATOM 6622 N N   . LYS D 4 29  ? 99.226  105.335 172.883 1.00 108.11 ? 29  LYS G N   1 
ATOM 6623 C CA  . LYS D 4 29  ? 98.391  104.887 171.776 1.00 109.00 ? 29  LYS G CA  1 
ATOM 6624 C C   . LYS D 4 29  ? 98.542  105.810 170.573 1.00 107.90 ? 29  LYS G C   1 
ATOM 6625 O O   . LYS D 4 29  ? 98.612  107.034 170.711 1.00 107.90 ? 29  LYS G O   1 
ATOM 6626 C CB  . LYS D 4 29  ? 96.928  104.832 172.217 1.00 107.43 ? 29  LYS G CB  1 
ATOM 6627 C CG  . LYS D 4 29  ? 96.482  103.475 172.739 1.00 105.57 ? 29  LYS G CG  1 
ATOM 6628 C CD  . LYS D 4 29  ? 95.071  103.531 173.313 1.00 106.02 ? 29  LYS G CD  1 
ATOM 6629 C CE  . LYS D 4 29  ? 94.166  104.453 172.509 1.00 107.98 ? 29  LYS G CE  1 
ATOM 6630 N NZ  . LYS D 4 29  ? 92.734  104.061 172.618 1.00 109.36 ? 29  LYS G NZ  1 
ATOM 6631 N N   . VAL D 4 30  ? 98.602  105.208 169.381 1.00 101.67 ? 30  VAL G N   1 
ATOM 6632 C CA  . VAL D 4 30  ? 98.819  105.973 168.159 1.00 100.39 ? 30  VAL G CA  1 
ATOM 6633 C C   . VAL D 4 30  ? 97.684  106.945 167.885 1.00 101.55 ? 30  VAL G C   1 
ATOM 6634 O O   . VAL D 4 30  ? 97.890  107.954 167.204 1.00 103.14 ? 30  VAL G O   1 
ATOM 6635 C CB  . VAL D 4 30  ? 99.022  105.028 166.957 1.00 100.39 ? 30  VAL G CB  1 
ATOM 6636 C CG1 . VAL D 4 30  ? 100.321 104.259 167.104 1.00 99.15  ? 30  VAL G CG1 1 
ATOM 6637 C CG2 . VAL D 4 30  ? 97.842  104.081 166.818 1.00 101.75 ? 30  VAL G CG2 1 
ATOM 6638 N N   . SER D 4 31  ? 96.481  106.664 168.390 1.00 105.14 ? 31  SER G N   1 
ATOM 6639 C CA  . SER D 4 31  ? 95.369  107.588 168.196 1.00 106.85 ? 31  SER G CA  1 
ATOM 6640 C C   . SER D 4 31  ? 95.651  108.930 168.860 1.00 108.12 ? 31  SER G C   1 
ATOM 6641 O O   . SER D 4 31  ? 95.453  109.990 168.255 1.00 107.14 ? 31  SER G O   1 
ATOM 6642 C CB  . SER D 4 31  ? 94.078  106.976 168.740 1.00 107.78 ? 31  SER G CB  1 
ATOM 6643 O OG  . SER D 4 31  ? 92.978  107.845 168.533 1.00 106.98 ? 31  SER G OG  1 
ATOM 6644 N N   . LYS D 4 32  ? 96.138  108.901 170.102 1.00 103.59 ? 32  LYS G N   1 
ATOM 6645 C CA  . LYS D 4 32  ? 96.441  110.141 170.809 1.00 103.09 ? 32  LYS G CA  1 
ATOM 6646 C C   . LYS D 4 32  ? 97.589  110.893 170.145 1.00 100.14 ? 32  LYS G C   1 
ATOM 6647 O O   . LYS D 4 32  ? 97.548  112.123 170.030 1.00 98.57  ? 32  LYS G O   1 
ATOM 6648 C CB  . LYS D 4 32  ? 96.766  109.841 172.273 1.00 101.86 ? 32  LYS G CB  1 
ATOM 6649 C CG  . LYS D 4 32  ? 97.445  110.982 173.010 1.00 103.26 ? 32  LYS G CG  1 
ATOM 6650 C CD  . LYS D 4 32  ? 97.477  110.732 174.508 1.00 102.95 ? 32  LYS G CD  1 
ATOM 6651 C CE  . LYS D 4 32  ? 98.361  111.742 175.217 1.00 101.84 ? 32  LYS G CE  1 
ATOM 6652 N NZ  . LYS D 4 32  ? 98.411  111.500 176.685 1.00 103.59 ? 32  LYS G NZ  1 
ATOM 6653 N N   . ALA D 4 33  ? 98.622  110.172 169.705 1.00 93.08  ? 33  ALA G N   1 
ATOM 6654 C CA  . ALA D 4 33  ? 99.752  110.821 169.048 1.00 92.36  ? 33  ALA G CA  1 
ATOM 6655 C C   . ALA D 4 33  ? 99.335  111.464 167.730 1.00 95.62  ? 33  ALA G C   1 
ATOM 6656 O O   . ALA D 4 33  ? 99.742  112.593 167.421 1.00 100.35 ? 33  ALA G O   1 
ATOM 6657 C CB  . ALA D 4 33  ? 100.870 109.807 168.824 1.00 92.22  ? 33  ALA G CB  1 
ATOM 6658 N N   . ALA D 4 34  ? 98.523  110.760 166.939 1.00 98.27  ? 34  ALA G N   1 
ATOM 6659 C CA  . ALA D 4 34  ? 98.019  111.332 165.697 1.00 95.16  ? 34  ALA G CA  1 
ATOM 6660 C C   . ALA D 4 34  ? 97.134  112.539 165.971 1.00 96.88  ? 34  ALA G C   1 
ATOM 6661 O O   . ALA D 4 34  ? 97.177  113.530 165.233 1.00 96.93  ? 34  ALA G O   1 
ATOM 6662 C CB  . ALA D 4 34  ? 97.257  110.273 164.903 1.00 95.31  ? 34  ALA G CB  1 
ATOM 6663 N N   . ALA D 4 35  ? 96.320  112.474 167.029 1.00 98.47  ? 35  ALA G N   1 
ATOM 6664 C CA  . ALA D 4 35  ? 95.493  113.617 167.396 1.00 99.08  ? 35  ALA G CA  1 
ATOM 6665 C C   . ALA D 4 35  ? 96.349  114.816 167.782 1.00 97.51  ? 35  ALA G C   1 
ATOM 6666 O O   . ALA D 4 35  ? 96.029  115.954 167.426 1.00 96.82  ? 35  ALA G O   1 
ATOM 6667 C CB  . ALA D 4 35  ? 94.551  113.238 168.537 1.00 98.30  ? 35  ALA G CB  1 
ATOM 6668 N N   . ASP D 4 36  ? 97.437  114.582 168.519 1.00 90.87  ? 36  ASP G N   1 
ATOM 6669 C CA  . ASP D 4 36  ? 98.333  115.675 168.890 1.00 89.64  ? 36  ASP G CA  1 
ATOM 6670 C C   . ASP D 4 36  ? 98.998  116.286 167.663 1.00 86.00  ? 36  ASP G C   1 
ATOM 6671 O O   . ASP D 4 36  ? 99.121  117.514 167.556 1.00 90.88  ? 36  ASP G O   1 
ATOM 6672 C CB  . ASP D 4 36  ? 99.387  115.173 169.876 1.00 91.71  ? 36  ASP G CB  1 
ATOM 6673 C CG  . ASP D 4 36  ? 98.892  115.175 171.308 1.00 93.05  ? 36  ASP G CG  1 
ATOM 6674 O OD1 . ASP D 4 36  ? 97.661  115.194 171.512 1.00 93.76  ? 36  ASP G OD1 1 
ATOM 6675 O OD2 . ASP D 4 36  ? 99.735  115.156 172.230 1.00 90.11  ? 36  ASP G OD2 1 
ATOM 6676 N N   . LEU D 4 37  ? 99.440  115.442 166.728 1.00 80.17  ? 37  LEU G N   1 
ATOM 6677 C CA  . LEU D 4 37  ? 100.041 115.952 165.499 1.00 84.01  ? 37  LEU G CA  1 
ATOM 6678 C C   . LEU D 4 37  ? 99.037  116.777 164.700 1.00 88.44  ? 37  LEU G C   1 
ATOM 6679 O O   . LEU D 4 37  ? 99.369  117.855 164.191 1.00 87.11  ? 37  LEU G O   1 
ATOM 6680 C CB  . LEU D 4 37  ? 100.582 114.790 164.664 1.00 85.59  ? 37  LEU G CB  1 
ATOM 6681 C CG  . LEU D 4 37  ? 101.585 115.094 163.549 1.00 80.74  ? 37  LEU G CG  1 
ATOM 6682 C CD1 . LEU D 4 37  ? 102.566 113.943 163.403 1.00 76.23  ? 37  LEU G CD1 1 
ATOM 6683 C CD2 . LEU D 4 37  ? 100.877 115.356 162.231 1.00 84.40  ? 37  LEU G CD2 1 
ATOM 6684 N N   . MET D 4 38  ? 97.798  116.288 164.594 1.00 96.92  ? 38  MET G N   1 
ATOM 6685 C CA  . MET D 4 38  ? 96.748  117.045 163.920 1.00 93.99  ? 38  MET G CA  1 
ATOM 6686 C C   . MET D 4 38  ? 96.484  118.370 164.619 1.00 95.85  ? 38  MET G C   1 
ATOM 6687 O O   . MET D 4 38  ? 96.293  119.401 163.962 1.00 96.77  ? 38  MET G O   1 
ATOM 6688 C CB  . MET D 4 38  ? 95.462  116.223 163.863 1.00 94.03  ? 38  MET G CB  1 
ATOM 6689 C CG  . MET D 4 38  ? 94.709  116.325 162.552 1.00 96.74  ? 38  MET G CG  1 
ATOM 6690 S SD  . MET D 4 38  ? 93.264  115.251 162.531 1.00 104.50 ? 38  MET G SD  1 
ATOM 6691 C CE  . MET D 4 38  ? 92.119  116.208 163.520 1.00 96.47  ? 38  MET G CE  1 
ATOM 6692 N N   . ALA D 4 39  ? 96.450  118.358 165.952 1.00 91.10  ? 39  ALA G N   1 
ATOM 6693 C CA  . ALA D 4 39  ? 96.187  119.580 166.701 1.00 88.27  ? 39  ALA G CA  1 
ATOM 6694 C C   . ALA D 4 39  ? 97.271  120.616 166.455 1.00 87.96  ? 39  ALA G C   1 
ATOM 6695 O O   . ALA D 4 39  ? 96.972  121.797 166.250 1.00 89.20  ? 39  ALA G O   1 
ATOM 6696 C CB  . ALA D 4 39  ? 96.067  119.268 168.192 1.00 87.39  ? 39  ALA G CB  1 
ATOM 6697 N N   . TYR D 4 40  ? 98.538  120.196 166.462 1.00 78.76  ? 40  TYR G N   1 
ATOM 6698 C CA  . TYR D 4 40  ? 99.615  121.138 166.170 1.00 75.70  ? 40  TYR G CA  1 
ATOM 6699 C C   . TYR D 4 40  ? 99.511  121.666 164.744 1.00 77.17  ? 40  TYR G C   1 
ATOM 6700 O O   . TYR D 4 40  ? 99.630  122.876 164.504 1.00 85.18  ? 40  TYR G O   1 
ATOM 6701 C CB  . TYR D 4 40  ? 100.979 120.485 166.401 1.00 82.86  ? 40  TYR G CB  1 
ATOM 6702 C CG  . TYR D 4 40  ? 102.142 121.382 166.028 1.00 85.93  ? 40  TYR G CG  1 
ATOM 6703 C CD1 . TYR D 4 40  ? 102.675 122.278 166.944 1.00 82.99  ? 40  TYR G CD1 1 
ATOM 6704 C CD2 . TYR D 4 40  ? 102.707 121.331 164.760 1.00 84.56  ? 40  TYR G CD2 1 
ATOM 6705 C CE1 . TYR D 4 40  ? 103.732 123.101 166.606 1.00 81.40  ? 40  TYR G CE1 1 
ATOM 6706 C CE2 . TYR D 4 40  ? 103.763 122.149 164.415 1.00 80.50  ? 40  TYR G CE2 1 
ATOM 6707 C CZ  . TYR D 4 40  ? 104.272 123.030 165.341 1.00 80.33  ? 40  TYR G CZ  1 
ATOM 6708 O OH  . TYR D 4 40  ? 105.326 123.845 164.999 1.00 79.52  ? 40  TYR G OH  1 
ATOM 6709 N N   . CYS D 4 41  ? 99.292  120.768 163.779 1.00 82.15  ? 41  CYS G N   1 
ATOM 6710 C CA  . CYS D 4 41  ? 99.255  121.176 162.380 1.00 85.80  ? 41  CYS G CA  1 
ATOM 6711 C C   . CYS D 4 41  ? 98.069  122.076 162.066 1.00 88.02  ? 41  CYS G C   1 
ATOM 6712 O O   . CYS D 4 41  ? 98.137  122.858 161.112 1.00 84.17  ? 41  CYS G O   1 
ATOM 6713 C CB  . CYS D 4 41  ? 99.228  119.946 161.475 1.00 89.71  ? 41  CYS G CB  1 
ATOM 6714 S SG  . CYS D 4 41  ? 99.575  120.301 159.744 1.00 101.23 ? 41  CYS G SG  1 
ATOM 6715 N N   . GLU D 4 42  ? 96.986  121.980 162.836 1.00 95.04  ? 42  GLU G N   1 
ATOM 6716 C CA  . GLU D 4 42  ? 95.850  122.873 162.656 1.00 91.50  ? 42  GLU G CA  1 
ATOM 6717 C C   . GLU D 4 42  ? 95.997  124.172 163.434 1.00 90.65  ? 42  GLU G C   1 
ATOM 6718 O O   . GLU D 4 42  ? 95.542  125.221 162.963 1.00 93.40  ? 42  GLU G O   1 
ATOM 6719 C CB  . GLU D 4 42  ? 94.553  122.172 163.073 1.00 92.92  ? 42  GLU G CB  1 
ATOM 6720 C CG  . GLU D 4 42  ? 94.130  121.048 162.141 1.00 94.47  ? 42  GLU G CG  1 
ATOM 6721 C CD  . GLU D 4 42  ? 92.624  120.948 161.995 1.00 93.97  ? 42  GLU G CD  1 
ATOM 6722 O OE1 . GLU D 4 42  ? 91.905  121.479 162.867 1.00 95.72  ? 42  GLU G OE1 1 
ATOM 6723 O OE2 . GLU D 4 42  ? 92.160  120.339 161.009 1.00 93.17  ? 42  GLU G OE2 1 
ATOM 6724 N N   . ALA D 4 43  ? 96.618  124.130 164.615 1.00 86.16  ? 43  ALA G N   1 
ATOM 6725 C CA  . ALA D 4 43  ? 96.801  125.344 165.401 1.00 86.47  ? 43  ALA G CA  1 
ATOM 6726 C C   . ALA D 4 43  ? 97.799  126.283 164.738 1.00 87.88  ? 43  ALA G C   1 
ATOM 6727 O O   . ALA D 4 43  ? 97.535  127.482 164.596 1.00 92.06  ? 43  ALA G O   1 
ATOM 6728 C CB  . ALA D 4 43  ? 97.251  124.989 166.818 1.00 87.76  ? 43  ALA G CB  1 
ATOM 6729 N N   . HIS D 4 44  ? 98.952  125.762 164.326 1.00 84.69  ? 44  HIS G N   1 
ATOM 6730 C CA  . HIS D 4 44  ? 99.960  126.611 163.689 1.00 82.74  ? 44  HIS G CA  1 
ATOM 6731 C C   . HIS D 4 44  ? 99.801  126.631 162.173 1.00 85.42  ? 44  HIS G C   1 
ATOM 6732 O O   . HIS D 4 44  ? 100.763 126.456 161.430 1.00 89.15  ? 44  HIS G O   1 
ATOM 6733 C CB  . HIS D 4 44  ? 101.357 126.149 164.082 1.00 83.71  ? 44  HIS G CB  1 
ATOM 6734 C CG  . HIS D 4 44  ? 101.679 126.352 165.529 1.00 86.60  ? 44  HIS G CG  1 
ATOM 6735 N ND1 . HIS D 4 44  ? 101.052 125.652 166.537 1.00 88.79  ? 44  HIS G ND1 1 
ATOM 6736 C CD2 . HIS D 4 44  ? 102.565 127.175 166.137 1.00 90.10  ? 44  HIS G CD2 1 
ATOM 6737 C CE1 . HIS D 4 44  ? 101.538 126.036 167.704 1.00 88.51  ? 44  HIS G CE1 1 
ATOM 6738 N NE2 . HIS D 4 44  ? 102.457 126.960 167.489 1.00 89.19  ? 44  HIS G NE2 1 
ATOM 6739 N N   . ALA D 4 45  ? 98.581  126.881 161.699 1.00 83.38  ? 45  ALA G N   1 
ATOM 6740 C CA  . ALA D 4 45  ? 98.299  126.860 160.270 1.00 83.54  ? 45  ALA G CA  1 
ATOM 6741 C C   . ALA D 4 45  ? 98.206  128.246 159.649 1.00 86.56  ? 45  ALA G C   1 
ATOM 6742 O O   . ALA D 4 45  ? 98.391  128.375 158.434 1.00 86.76  ? 45  ALA G O   1 
ATOM 6743 C CB  . ALA D 4 45  ? 96.995  126.102 159.996 1.00 86.81  ? 45  ALA G CB  1 
ATOM 6744 N N   . LYS D 4 46  ? 97.926  129.278 160.445 1.00 99.60  ? 46  LYS G N   1 
ATOM 6745 C CA  . LYS D 4 46  ? 97.807  130.633 159.925 1.00 100.55 ? 46  LYS G CA  1 
ATOM 6746 C C   . LYS D 4 46  ? 99.154  131.292 159.658 1.00 101.05 ? 46  LYS G C   1 
ATOM 6747 O O   . LYS D 4 46  ? 99.189  132.362 159.042 1.00 101.16 ? 46  LYS G O   1 
ATOM 6748 C CB  . LYS D 4 46  ? 97.002  131.499 160.897 1.00 99.52  ? 46  LYS G CB  1 
ATOM 6749 C CG  . LYS D 4 46  ? 95.580  131.016 161.125 1.00 101.70 ? 46  LYS G CG  1 
ATOM 6750 C CD  . LYS D 4 46  ? 94.773  131.046 159.837 1.00 101.42 ? 46  LYS G CD  1 
ATOM 6751 C CE  . LYS D 4 46  ? 94.559  132.471 159.350 1.00 100.48 ? 46  LYS G CE  1 
ATOM 6752 N NZ  . LYS D 4 46  ? 93.733  133.267 160.299 1.00 100.36 ? 46  LYS G NZ  1 
ATOM 6753 N N   . GLU D 4 47  ? 100.256 130.687 160.101 1.00 91.84  ? 47  GLU G N   1 
ATOM 6754 C CA  . GLU D 4 47  ? 101.584 131.271 159.970 1.00 87.74  ? 47  GLU G CA  1 
ATOM 6755 C C   . GLU D 4 47  ? 102.445 130.523 158.955 1.00 85.89  ? 47  GLU G C   1 
ATOM 6756 O O   . GLU D 4 47  ? 103.673 130.513 159.062 1.00 88.03  ? 47  GLU G O   1 
ATOM 6757 C CB  . GLU D 4 47  ? 102.278 131.312 161.330 1.00 90.86  ? 47  GLU G CB  1 
ATOM 6758 C CG  . GLU D 4 47  ? 101.376 131.772 162.466 1.00 91.78  ? 47  GLU G CG  1 
ATOM 6759 C CD  . GLU D 4 47  ? 102.066 131.737 163.815 1.00 91.41  ? 47  GLU G CD  1 
ATOM 6760 O OE1 . GLU D 4 47  ? 102.403 130.630 164.284 1.00 90.85  ? 47  GLU G OE1 1 
ATOM 6761 O OE2 . GLU D 4 47  ? 102.270 132.817 164.408 1.00 94.29  ? 47  GLU G OE2 1 
ATOM 6762 N N   . ASP D 4 48  ? 101.816 129.892 157.966 1.00 75.89  ? 48  ASP G N   1 
ATOM 6763 C CA  . ASP D 4 48  ? 102.545 129.133 156.957 1.00 78.37  ? 48  ASP G CA  1 
ATOM 6764 C C   . ASP D 4 48  ? 102.463 129.846 155.617 1.00 78.02  ? 48  ASP G C   1 
ATOM 6765 O O   . ASP D 4 48  ? 101.398 129.834 154.979 1.00 79.33  ? 48  ASP G O   1 
ATOM 6766 C CB  . ASP D 4 48  ? 101.985 127.715 156.840 1.00 81.29  ? 48  ASP G CB  1 
ATOM 6767 C CG  . ASP D 4 48  ? 102.918 126.776 156.097 1.00 79.99  ? 48  ASP G CG  1 
ATOM 6768 O OD1 . ASP D 4 48  ? 103.998 127.227 155.661 1.00 79.21  ? 48  ASP G OD1 1 
ATOM 6769 O OD2 . ASP D 4 48  ? 102.575 125.584 155.954 1.00 76.81  ? 48  ASP G OD2 1 
ATOM 6770 N N   . PRO D 4 49  ? 103.542 130.479 155.147 1.00 71.09  ? 49  PRO G N   1 
ATOM 6771 C CA  . PRO D 4 49  ? 103.507 131.129 153.829 1.00 70.83  ? 49  PRO G CA  1 
ATOM 6772 C C   . PRO D 4 49  ? 103.502 130.157 152.662 1.00 75.87  ? 49  PRO G C   1 
ATOM 6773 O O   . PRO D 4 49  ? 103.445 130.603 151.511 1.00 76.84  ? 49  PRO G O   1 
ATOM 6774 C CB  . PRO D 4 49  ? 104.789 131.980 153.824 1.00 73.59  ? 49  PRO G CB  1 
ATOM 6775 C CG  . PRO D 4 49  ? 105.245 132.027 155.253 1.00 75.07  ? 49  PRO G CG  1 
ATOM 6776 C CD  . PRO D 4 49  ? 104.797 130.746 155.862 1.00 72.62  ? 49  PRO G CD  1 
ATOM 6777 N N   . LEU D 4 50  ? 103.571 128.850 152.914 1.00 79.59  ? 50  LEU G N   1 
ATOM 6778 C CA  . LEU D 4 50  ? 103.553 127.841 151.862 1.00 77.79  ? 50  LEU G CA  1 
ATOM 6779 C C   . LEU D 4 50  ? 102.185 127.193 151.700 1.00 78.14  ? 50  LEU G C   1 
ATOM 6780 O O   . LEU D 4 50  ? 101.697 127.045 150.575 1.00 81.35  ? 50  LEU G O   1 
ATOM 6781 C CB  . LEU D 4 50  ? 104.607 126.766 152.151 1.00 74.19  ? 50  LEU G CB  1 
ATOM 6782 C CG  . LEU D 4 50  ? 106.066 127.157 151.922 1.00 75.76  ? 50  LEU G CG  1 
ATOM 6783 C CD1 . LEU D 4 50  ? 106.984 126.116 152.530 1.00 76.21  ? 50  LEU G CD1 1 
ATOM 6784 C CD2 . LEU D 4 50  ? 106.351 127.326 150.440 1.00 70.69  ? 50  LEU G CD2 1 
ATOM 6785 N N   . LEU D 4 51  ? 101.558 126.790 152.808 1.00 76.66  ? 51  LEU G N   1 
ATOM 6786 C CA  . LEU D 4 51  ? 100.227 126.196 152.737 1.00 74.79  ? 51  LEU G CA  1 
ATOM 6787 C C   . LEU D 4 51  ? 99.209  127.199 152.211 1.00 79.40  ? 51  LEU G C   1 
ATOM 6788 O O   . LEU D 4 51  ? 98.384  126.873 151.349 1.00 82.37  ? 51  LEU G O   1 
ATOM 6789 C CB  . LEU D 4 51  ? 99.815  125.680 154.115 1.00 72.47  ? 51  LEU G CB  1 
ATOM 6790 C CG  . LEU D 4 51  ? 98.652  124.690 154.141 1.00 75.77  ? 51  LEU G CG  1 
ATOM 6791 C CD1 . LEU D 4 51  ? 99.022  123.427 153.384 1.00 81.06  ? 51  LEU G CD1 1 
ATOM 6792 C CD2 . LEU D 4 51  ? 98.256  124.370 155.572 1.00 77.26  ? 51  LEU G CD2 1 
ATOM 6793 N N   . THR D 4 52  ? 99.253  128.428 152.720 1.00 91.75  ? 52  THR G N   1 
ATOM 6794 C CA  . THR D 4 52  ? 98.393  129.505 152.255 1.00 91.68  ? 52  THR G CA  1 
ATOM 6795 C C   . THR D 4 52  ? 99.252  130.567 151.591 1.00 91.54  ? 52  THR G C   1 
ATOM 6796 O O   . THR D 4 52  ? 100.136 131.133 152.251 1.00 91.24  ? 52  THR G O   1 
ATOM 6797 C CB  . THR D 4 52  ? 97.599  130.110 153.412 1.00 94.29  ? 52  THR G CB  1 
ATOM 6798 O OG1 . THR D 4 52  ? 98.502  130.681 154.368 1.00 92.67  ? 52  THR G OG1 1 
ATOM 6799 C CG2 . THR D 4 52  ? 96.757  129.044 154.093 1.00 94.77  ? 52  THR G CG2 1 
ATOM 6800 N N   . PRO D 4 53  ? 99.052  130.856 150.305 1.00 101.84 ? 53  PRO G N   1 
ATOM 6801 C CA  . PRO D 4 53  ? 99.905  131.842 149.631 1.00 103.50 ? 53  PRO G CA  1 
ATOM 6802 C C   . PRO D 4 53  ? 99.837  133.203 150.308 1.00 103.60 ? 53  PRO G C   1 
ATOM 6803 O O   . PRO D 4 53  ? 98.768  133.674 150.698 1.00 102.66 ? 53  PRO G O   1 
ATOM 6804 C CB  . PRO D 4 53  ? 99.334  131.891 148.209 1.00 101.51 ? 53  PRO G CB  1 
ATOM 6805 C CG  . PRO D 4 53  ? 98.648  130.577 148.032 1.00 104.33 ? 53  PRO G CG  1 
ATOM 6806 C CD  . PRO D 4 53  ? 98.096  130.223 149.381 1.00 102.02 ? 53  PRO G CD  1 
ATOM 6807 N N   . VAL D 4 54  ? 101.001 133.830 150.443 1.00 105.64 ? 54  VAL G N   1 
ATOM 6808 C CA  . VAL D 4 54  ? 101.126 135.132 151.092 1.00 105.48 ? 54  VAL G CA  1 
ATOM 6809 C C   . VAL D 4 54  ? 100.712 136.210 150.096 1.00 107.69 ? 54  VAL G C   1 
ATOM 6810 O O   . VAL D 4 54  ? 100.882 136.026 148.881 1.00 106.29 ? 54  VAL G O   1 
ATOM 6811 C CB  . VAL D 4 54  ? 102.557 135.346 151.618 1.00 104.12 ? 54  VAL G CB  1 
ATOM 6812 C CG1 . VAL D 4 54  ? 103.506 135.727 150.488 1.00 103.54 ? 54  VAL G CG1 1 
ATOM 6813 C CG2 . VAL D 4 54  ? 102.588 136.384 152.732 1.00 104.59 ? 54  VAL G CG2 1 
ATOM 6814 N N   . PRO D 4 55  ? 100.129 137.322 150.546 1.00 108.44 ? 55  PRO G N   1 
ATOM 6815 C CA  . PRO D 4 55  ? 99.885  138.441 149.629 1.00 104.51 ? 55  PRO G CA  1 
ATOM 6816 C C   . PRO D 4 55  ? 101.187 138.974 149.053 1.00 105.25 ? 55  PRO G C   1 
ATOM 6817 O O   . PRO D 4 55  ? 102.237 138.948 149.700 1.00 107.53 ? 55  PRO G O   1 
ATOM 6818 C CB  . PRO D 4 55  ? 99.195  139.482 150.517 1.00 106.23 ? 55  PRO G CB  1 
ATOM 6819 C CG  . PRO D 4 55  ? 98.524  138.675 151.570 1.00 105.99 ? 55  PRO G CG  1 
ATOM 6820 C CD  . PRO D 4 55  ? 99.429  137.502 151.830 1.00 107.31 ? 55  PRO G CD  1 
ATOM 6821 N N   . ALA D 4 56  ? 101.108 139.462 147.813 1.00 104.26 ? 56  ALA G N   1 
ATOM 6822 C CA  . ALA D 4 56  ? 102.300 139.922 147.109 1.00 104.88 ? 56  ALA G CA  1 
ATOM 6823 C C   . ALA D 4 56  ? 102.968 141.105 147.798 1.00 105.22 ? 56  ALA G C   1 
ATOM 6824 O O   . ALA D 4 56  ? 104.148 141.369 147.542 1.00 105.15 ? 56  ALA G O   1 
ATOM 6825 C CB  . ALA D 4 56  ? 101.949 140.293 145.668 1.00 105.05 ? 56  ALA G CB  1 
ATOM 6826 N N   . SER D 4 57  ? 102.246 141.823 148.659 1.00 105.29 ? 57  SER G N   1 
ATOM 6827 C CA  . SER D 4 57  ? 102.840 142.937 149.387 1.00 106.72 ? 57  SER G CA  1 
ATOM 6828 C C   . SER D 4 57  ? 103.771 142.480 150.501 1.00 103.55 ? 57  SER G C   1 
ATOM 6829 O O   . SER D 4 57  ? 104.657 143.243 150.900 1.00 103.81 ? 57  SER G O   1 
ATOM 6830 C CB  . SER D 4 57  ? 101.743 143.831 149.969 1.00 106.61 ? 57  SER G CB  1 
ATOM 6831 O OG  . SER D 4 57  ? 100.821 143.074 150.734 1.00 106.09 ? 57  SER G OG  1 
ATOM 6832 N N   . GLU D 4 58  ? 103.596 141.259 151.006 1.00 99.17  ? 58  GLU G N   1 
ATOM 6833 C CA  . GLU D 4 58  ? 104.408 140.727 152.093 1.00 100.55 ? 58  GLU G CA  1 
ATOM 6834 C C   . GLU D 4 58  ? 105.268 139.550 151.641 1.00 100.04 ? 58  GLU G C   1 
ATOM 6835 O O   . GLU D 4 58  ? 105.582 138.661 152.435 1.00 101.01 ? 58  GLU G O   1 
ATOM 6836 C CB  . GLU D 4 58  ? 103.522 140.317 153.269 1.00 99.70  ? 58  GLU G CB  1 
ATOM 6837 N N   . ASN D 4 59  ? 105.656 139.534 150.367 1.00 84.55  ? 59  ASN G N   1 
ATOM 6838 C CA  . ASN D 4 59  ? 106.487 138.468 149.817 1.00 82.84  ? 59  ASN G CA  1 
ATOM 6839 C C   . ASN D 4 59  ? 107.849 139.037 149.446 1.00 84.77  ? 59  ASN G C   1 
ATOM 6840 O O   . ASN D 4 59  ? 107.990 139.666 148.386 1.00 85.72  ? 59  ASN G O   1 
ATOM 6841 C CB  . ASN D 4 59  ? 105.815 137.840 148.592 1.00 81.50  ? 59  ASN G CB  1 
ATOM 6842 C CG  . ASN D 4 59  ? 106.554 136.620 148.081 1.00 83.66  ? 59  ASN G CG  1 
ATOM 6843 O OD1 . ASN D 4 59  ? 107.527 136.171 148.684 1.00 83.12  ? 59  ASN G OD1 1 
ATOM 6844 N ND2 . ASN D 4 59  ? 106.093 136.078 146.961 1.00 84.07  ? 59  ASN G ND2 1 
ATOM 6845 N N   . PRO D 4 60  ? 108.878 138.851 150.276 1.00 71.23  ? 60  PRO G N   1 
ATOM 6846 C CA  . PRO D 4 60  ? 110.200 139.408 149.944 1.00 67.42  ? 60  PRO G CA  1 
ATOM 6847 C C   . PRO D 4 60  ? 110.808 138.830 148.679 1.00 66.17  ? 60  PRO G C   1 
ATOM 6848 O O   . PRO D 4 60  ? 111.665 139.481 148.069 1.00 64.42  ? 60  PRO G O   1 
ATOM 6849 C CB  . PRO D 4 60  ? 111.045 139.067 151.179 1.00 64.73  ? 60  PRO G CB  1 
ATOM 6850 C CG  . PRO D 4 60  ? 110.350 137.909 151.807 1.00 64.64  ? 60  PRO G CG  1 
ATOM 6851 C CD  . PRO D 4 60  ? 108.889 138.112 151.549 1.00 67.78  ? 60  PRO G CD  1 
ATOM 6852 N N   . PHE D 4 61  ? 110.398 137.637 148.265 1.00 66.18  ? 61  PHE G N   1 
ATOM 6853 C CA  . PHE D 4 61  ? 110.947 137.013 147.068 1.00 69.51  ? 61  PHE G CA  1 
ATOM 6854 C C   . PHE D 4 61  ? 110.110 137.346 145.837 1.00 69.49  ? 61  PHE G C   1 
ATOM 6855 O O   . PHE D 4 61  ? 109.300 138.272 145.857 1.00 67.34  ? 61  PHE G O   1 
ATOM 6856 C CB  . PHE D 4 61  ? 111.035 135.498 147.254 1.00 67.65  ? 61  PHE G CB  1 
ATOM 6857 C CG  . PHE D 4 61  ? 111.958 135.080 148.359 1.00 67.96  ? 61  PHE G CG  1 
ATOM 6858 C CD1 . PHE D 4 61  ? 113.323 135.023 148.153 1.00 59.50  ? 61  PHE G CD1 1 
ATOM 6859 C CD2 . PHE D 4 61  ? 111.460 134.755 149.608 1.00 67.63  ? 61  PHE G CD2 1 
ATOM 6860 C CE1 . PHE D 4 61  ? 114.174 134.645 149.169 1.00 58.40  ? 61  PHE G CE1 1 
ATOM 6861 C CE2 . PHE D 4 61  ? 112.308 134.376 150.629 1.00 63.39  ? 61  PHE G CE2 1 
ATOM 6862 C CZ  . PHE D 4 61  ? 113.666 134.320 150.409 1.00 66.42  ? 61  PHE G CZ  1 
ATOM 6863 N N   . ASP E 5 1   ? 147.660 141.752 164.471 1.00 93.49  ? 1   ASP S N   1 
ATOM 6864 C CA  . ASP E 5 1   ? 147.090 143.036 164.859 1.00 93.84  ? 1   ASP S CA  1 
ATOM 6865 C C   . ASP E 5 1   ? 146.834 143.923 163.647 1.00 93.66  ? 1   ASP S C   1 
ATOM 6866 O O   . ASP E 5 1   ? 147.720 144.126 162.816 1.00 95.34  ? 1   ASP S O   1 
ATOM 6867 C CB  . ASP E 5 1   ? 148.012 143.758 165.844 1.00 97.22  ? 1   ASP S CB  1 
ATOM 6868 C CG  . ASP E 5 1   ? 147.951 143.169 167.239 1.00 99.11  ? 1   ASP S CG  1 
ATOM 6869 O OD1 . ASP E 5 1   ? 146.881 142.649 167.619 1.00 98.67  ? 1   ASP S OD1 1 
ATOM 6870 O OD2 . ASP E 5 1   ? 148.971 143.230 167.957 1.00 99.89  ? 1   ASP S OD2 1 
ATOM 6871 N N   . VAL E 5 2   ? 145.618 144.447 163.550 1.00 74.46  ? 2   VAL S N   1 
ATOM 6872 C CA  . VAL E 5 2   ? 145.276 145.393 162.495 1.00 74.32  ? 2   VAL S CA  1 
ATOM 6873 C C   . VAL E 5 2   ? 145.884 146.745 162.835 1.00 76.74  ? 2   VAL S C   1 
ATOM 6874 O O   . VAL E 5 2   ? 145.700 147.263 163.943 1.00 80.17  ? 2   VAL S O   1 
ATOM 6875 C CB  . VAL E 5 2   ? 143.752 145.494 162.326 1.00 73.80  ? 2   VAL S CB  1 
ATOM 6876 C CG1 . VAL E 5 2   ? 143.402 146.557 161.299 1.00 71.30  ? 2   VAL S CG1 1 
ATOM 6877 C CG2 . VAL E 5 2   ? 143.180 144.149 161.919 1.00 72.93  ? 2   VAL S CG2 1 
ATOM 6878 N N   . GLN E 5 3   ? 146.617 147.321 161.885 1.00 74.83  ? 3   GLN S N   1 
ATOM 6879 C CA  . GLN E 5 3   ? 147.288 148.592 162.116 1.00 71.59  ? 3   GLN S CA  1 
ATOM 6880 C C   . GLN E 5 3   ? 147.330 149.389 160.823 1.00 74.69  ? 3   GLN S C   1 
ATOM 6881 O O   . GLN E 5 3   ? 147.781 148.880 159.793 1.00 74.91  ? 3   GLN S O   1 
ATOM 6882 C CB  . GLN E 5 3   ? 148.707 148.375 162.651 1.00 73.09  ? 3   GLN S CB  1 
ATOM 6883 C CG  . GLN E 5 3   ? 149.176 149.449 163.616 1.00 77.41  ? 3   GLN S CG  1 
ATOM 6884 C CD  . GLN E 5 3   ? 150.670 149.394 163.864 1.00 79.53  ? 3   GLN S CD  1 
ATOM 6885 O OE1 . GLN E 5 3   ? 151.465 149.341 162.925 1.00 77.87  ? 3   GLN S OE1 1 
ATOM 6886 N NE2 . GLN E 5 3   ? 151.060 149.407 165.133 1.00 77.53  ? 3   GLN S NE2 1 
ATOM 6887 N N   . LEU E 5 4   ? 146.859 150.632 160.884 1.00 76.57  ? 4   LEU S N   1 
ATOM 6888 C CA  . LEU E 5 4   ? 146.961 151.578 159.781 1.00 72.44  ? 4   LEU S CA  1 
ATOM 6889 C C   . LEU E 5 4   ? 147.826 152.742 160.236 1.00 72.96  ? 4   LEU S C   1 
ATOM 6890 O O   . LEU E 5 4   ? 147.455 153.469 161.164 1.00 79.62  ? 4   LEU S O   1 
ATOM 6891 C CB  . LEU E 5 4   ? 145.581 152.071 159.341 1.00 64.70  ? 4   LEU S CB  1 
ATOM 6892 C CG  . LEU E 5 4   ? 144.672 151.076 158.620 1.00 67.35  ? 4   LEU S CG  1 
ATOM 6893 C CD1 . LEU E 5 4   ? 143.221 151.487 158.756 1.00 70.18  ? 4   LEU S CD1 1 
ATOM 6894 C CD2 . LEU E 5 4   ? 145.055 150.987 157.160 1.00 67.21  ? 4   LEU S CD2 1 
ATOM 6895 N N   . VAL E 5 5   ? 148.973 152.917 159.588 1.00 76.50  ? 5   VAL S N   1 
ATOM 6896 C CA  . VAL E 5 5   ? 149.902 153.994 159.903 1.00 76.47  ? 5   VAL S CA  1 
ATOM 6897 C C   . VAL E 5 5   ? 150.216 154.739 158.615 1.00 80.12  ? 5   VAL S C   1 
ATOM 6898 O O   . VAL E 5 5   ? 150.487 154.116 157.582 1.00 86.22  ? 5   VAL S O   1 
ATOM 6899 C CB  . VAL E 5 5   ? 151.190 153.469 160.569 1.00 78.79  ? 5   VAL S CB  1 
ATOM 6900 C CG1 . VAL E 5 5   ? 151.786 152.320 159.767 1.00 82.40  ? 5   VAL S CG1 1 
ATOM 6901 C CG2 . VAL E 5 5   ? 152.200 154.594 160.744 1.00 79.12  ? 5   VAL S CG2 1 
ATOM 6902 N N   . GLU E 5 6   ? 150.156 156.066 158.670 1.00 83.63  ? 6   GLU S N   1 
ATOM 6903 C CA  . GLU E 5 6   ? 150.336 156.904 157.496 1.00 84.86  ? 6   GLU S CA  1 
ATOM 6904 C C   . GLU E 5 6   ? 151.332 158.017 157.787 1.00 83.91  ? 6   GLU S C   1 
ATOM 6905 O O   . GLU E 5 6   ? 151.429 158.513 158.913 1.00 83.40  ? 6   GLU S O   1 
ATOM 6906 C CB  . GLU E 5 6   ? 148.996 157.484 157.030 1.00 84.45  ? 6   GLU S CB  1 
ATOM 6907 C CG  . GLU E 5 6   ? 148.375 158.443 158.015 1.00 83.93  ? 6   GLU S CG  1 
ATOM 6908 C CD  . GLU E 5 6   ? 147.320 157.767 158.863 1.00 85.37  ? 6   GLU S CD  1 
ATOM 6909 O OE1 . GLU E 5 6   ? 146.730 156.773 158.395 1.00 87.84  ? 6   GLU S OE1 1 
ATOM 6910 O OE2 . GLU E 5 6   ? 147.095 158.211 160.003 1.00 80.82  ? 6   GLU S OE2 1 
ATOM 6911 N N   . SER E 5 7   ? 152.080 158.396 156.753 1.00 89.50  ? 7   SER S N   1 
ATOM 6912 C CA  . SER E 5 7   ? 153.115 159.411 156.864 1.00 92.02  ? 7   SER S CA  1 
ATOM 6913 C C   . SER E 5 7   ? 153.089 160.298 155.629 1.00 90.80  ? 7   SER S C   1 
ATOM 6914 O O   . SER E 5 7   ? 152.487 159.961 154.607 1.00 87.87  ? 7   SER S O   1 
ATOM 6915 C CB  . SER E 5 7   ? 154.505 158.786 157.035 1.00 93.83  ? 7   SER S CB  1 
ATOM 6916 O OG  . SER E 5 7   ? 155.524 159.736 156.775 1.00 95.70  ? 7   SER S OG  1 
ATOM 6917 N N   . GLY E 5 8   ? 153.758 161.443 155.737 1.00 93.84  ? 8   GLY S N   1 
ATOM 6918 C CA  . GLY E 5 8   ? 153.827 162.388 154.642 1.00 95.00  ? 8   GLY S CA  1 
ATOM 6919 C C   . GLY E 5 8   ? 153.408 163.787 155.042 1.00 95.87  ? 8   GLY S C   1 
ATOM 6920 O O   . GLY E 5 8   ? 153.503 164.724 154.244 1.00 93.50  ? 8   GLY S O   1 
ATOM 6921 N N   . GLY E 5 9   ? 152.944 163.942 156.281 1.00 94.28  ? 9   GLY S N   1 
ATOM 6922 C CA  . GLY E 5 9   ? 152.522 165.239 156.759 1.00 95.40  ? 9   GLY S CA  1 
ATOM 6923 C C   . GLY E 5 9   ? 153.687 166.157 157.072 1.00 94.13  ? 9   GLY S C   1 
ATOM 6924 O O   . GLY E 5 9   ? 154.840 165.742 157.179 1.00 94.26  ? 9   GLY S O   1 
ATOM 6925 N N   . GLY E 5 10  ? 153.367 167.434 157.220 1.00 95.17  ? 10  GLY S N   1 
ATOM 6926 C CA  . GLY E 5 10  ? 154.374 168.428 157.520 1.00 95.31  ? 10  GLY S CA  1 
ATOM 6927 C C   . GLY E 5 10  ? 153.934 169.795 157.033 1.00 96.94  ? 10  GLY S C   1 
ATOM 6928 O O   . GLY E 5 10  ? 152.805 169.985 156.582 1.00 98.00  ? 10  GLY S O   1 
ATOM 6929 N N   . LEU E 5 11  ? 154.862 170.743 157.135 1.00 103.75 ? 11  LEU S N   1 
ATOM 6930 C CA  . LEU E 5 11  ? 154.618 172.116 156.719 1.00 103.04 ? 11  LEU S CA  1 
ATOM 6931 C C   . LEU E 5 11  ? 154.932 172.265 155.236 1.00 102.22 ? 11  LEU S C   1 
ATOM 6932 O O   . LEU E 5 11  ? 156.034 171.930 154.791 1.00 103.08 ? 11  LEU S O   1 
ATOM 6933 C CB  . LEU E 5 11  ? 155.467 173.084 157.545 1.00 101.11 ? 11  LEU S CB  1 
ATOM 6934 C CG  . LEU E 5 11  ? 155.087 174.565 157.507 1.00 102.47 ? 11  LEU S CG  1 
ATOM 6935 C CD1 . LEU E 5 11  ? 155.275 175.188 158.880 1.00 101.46 ? 11  LEU S CD1 1 
ATOM 6936 C CD2 . LEU E 5 11  ? 155.904 175.313 156.466 1.00 103.90 ? 11  LEU S CD2 1 
ATOM 6937 N N   . VAL E 5 12  ? 153.960 172.764 154.475 1.00 104.24 ? 12  VAL S N   1 
ATOM 6938 C CA  . VAL E 5 12  ? 154.115 172.969 153.042 1.00 107.94 ? 12  VAL S CA  1 
ATOM 6939 C C   . VAL E 5 12  ? 153.635 174.371 152.691 1.00 109.24 ? 12  VAL S C   1 
ATOM 6940 O O   . VAL E 5 12  ? 152.788 174.950 153.379 1.00 110.27 ? 12  VAL S O   1 
ATOM 6941 C CB  . VAL E 5 12  ? 153.350 171.898 152.226 1.00 106.80 ? 12  VAL S CB  1 
ATOM 6942 C CG1 . VAL E 5 12  ? 151.853 172.153 152.267 1.00 106.47 ? 12  VAL S CG1 1 
ATOM 6943 C CG2 . VAL E 5 12  ? 153.853 171.849 150.790 1.00 107.23 ? 12  VAL S CG2 1 
ATOM 6944 N N   . GLN E 5 13  ? 154.203 174.925 151.623 1.00 114.62 ? 13  GLN S N   1 
ATOM 6945 C CA  . GLN E 5 13  ? 153.797 176.233 151.137 1.00 114.42 ? 13  GLN S CA  1 
ATOM 6946 C C   . GLN E 5 13  ? 152.564 176.112 150.242 1.00 113.67 ? 13  GLN S C   1 
ATOM 6947 O O   . GLN E 5 13  ? 152.320 175.057 149.649 1.00 112.76 ? 13  GLN S O   1 
ATOM 6948 C CB  . GLN E 5 13  ? 154.936 176.889 150.364 1.00 115.52 ? 13  GLN S CB  1 
ATOM 6949 C CG  . GLN E 5 13  ? 156.131 177.265 151.224 1.00 115.33 ? 13  GLN S CG  1 
ATOM 6950 C CD  . GLN E 5 13  ? 155.785 178.297 152.280 1.00 118.26 ? 13  GLN S CD  1 
ATOM 6951 O OE1 . GLN E 5 13  ? 155.071 179.262 152.010 1.00 119.93 ? 13  GLN S OE1 1 
ATOM 6952 N NE2 . GLN E 5 13  ? 156.290 178.096 153.492 1.00 116.15 ? 13  GLN S NE2 1 
ATOM 6953 N N   . PRO E 5 14  ? 151.763 177.173 150.141 1.00 106.23 ? 14  PRO S N   1 
ATOM 6954 C CA  . PRO E 5 14  ? 150.609 177.137 149.234 1.00 107.56 ? 14  PRO S CA  1 
ATOM 6955 C C   . PRO E 5 14  ? 151.044 176.932 147.790 1.00 106.25 ? 14  PRO S C   1 
ATOM 6956 O O   . PRO E 5 14  ? 152.077 177.443 147.353 1.00 106.82 ? 14  PRO S O   1 
ATOM 6957 C CB  . PRO E 5 14  ? 149.956 178.509 149.435 1.00 107.16 ? 14  PRO S CB  1 
ATOM 6958 C CG  . PRO E 5 14  ? 150.414 178.954 150.777 1.00 107.12 ? 14  PRO S CG  1 
ATOM 6959 C CD  . PRO E 5 14  ? 151.801 178.413 150.934 1.00 105.32 ? 14  PRO S CD  1 
ATOM 6960 N N   . GLY E 5 15  ? 150.238 176.173 147.049 1.00 105.51 ? 15  GLY S N   1 
ATOM 6961 C CA  . GLY E 5 15  ? 150.517 175.878 145.662 1.00 103.78 ? 15  GLY S CA  1 
ATOM 6962 C C   . GLY E 5 15  ? 151.398 174.671 145.427 1.00 106.05 ? 15  GLY S C   1 
ATOM 6963 O O   . GLY E 5 15  ? 151.584 174.278 144.268 1.00 106.87 ? 15  GLY S O   1 
ATOM 6964 N N   . GLY E 5 16  ? 151.944 174.070 146.482 1.00 110.29 ? 16  GLY S N   1 
ATOM 6965 C CA  . GLY E 5 16  ? 152.782 172.901 146.340 1.00 109.88 ? 16  GLY S CA  1 
ATOM 6966 C C   . GLY E 5 16  ? 151.980 171.619 146.238 1.00 111.52 ? 16  GLY S C   1 
ATOM 6967 O O   . GLY E 5 16  ? 150.751 171.602 146.301 1.00 110.64 ? 16  GLY S O   1 
ATOM 6968 N N   . SER E 5 17  ? 152.706 170.517 146.075 1.00 110.69 ? 17  SER S N   1 
ATOM 6969 C CA  . SER E 5 17  ? 152.116 169.191 145.960 1.00 110.37 ? 17  SER S CA  1 
ATOM 6970 C C   . SER E 5 17  ? 152.715 168.270 147.012 1.00 108.77 ? 17  SER S C   1 
ATOM 6971 O O   . SER E 5 17  ? 153.930 168.269 147.231 1.00 109.25 ? 17  SER S O   1 
ATOM 6972 C CB  . SER E 5 17  ? 152.341 168.604 144.562 1.00 110.61 ? 17  SER S CB  1 
ATOM 6973 O OG  . SER E 5 17  ? 151.946 169.518 143.555 1.00 110.75 ? 17  SER S OG  1 
ATOM 6974 N N   . ARG E 5 18  ? 151.856 167.488 147.663 1.00 96.81  ? 18  ARG S N   1 
ATOM 6975 C CA  . ARG E 5 18  ? 152.287 166.550 148.687 1.00 96.49  ? 18  ARG S CA  1 
ATOM 6976 C C   . ARG E 5 18  ? 151.511 165.251 148.536 1.00 97.78  ? 18  ARG S C   1 
ATOM 6977 O O   . ARG E 5 18  ? 150.337 165.251 148.156 1.00 96.49  ? 18  ARG S O   1 
ATOM 6978 C CB  . ARG E 5 18  ? 152.096 167.133 150.096 1.00 95.39  ? 18  ARG S CB  1 
ATOM 6979 C CG  . ARG E 5 18  ? 152.455 166.183 151.226 1.00 94.63  ? 18  ARG S CG  1 
ATOM 6980 C CD  . ARG E 5 18  ? 153.952 165.923 151.278 1.00 95.64  ? 18  ARG S CD  1 
ATOM 6981 N NE  . ARG E 5 18  ? 154.730 167.106 150.931 1.00 97.15  ? 18  ARG S NE  1 
ATOM 6982 C CZ  . ARG E 5 18  ? 155.038 168.075 151.783 1.00 96.97  ? 18  ARG S CZ  1 
ATOM 6983 N NH1 . ARG E 5 18  ? 154.649 168.033 153.047 1.00 97.12  ? 18  ARG S NH1 1 
ATOM 6984 N NH2 . ARG E 5 18  ? 155.756 169.109 151.356 1.00 95.97  ? 18  ARG S NH2 1 
ATOM 6985 N N   . LYS E 5 19  ? 152.181 164.141 148.835 1.00 90.92  ? 19  LYS S N   1 
ATOM 6986 C CA  . LYS E 5 19  ? 151.596 162.811 148.749 1.00 88.19  ? 19  LYS S CA  1 
ATOM 6987 C C   . LYS E 5 19  ? 151.613 162.166 150.127 1.00 90.19  ? 19  LYS S C   1 
ATOM 6988 O O   . LYS E 5 19  ? 152.630 162.216 150.826 1.00 88.68  ? 19  LYS S O   1 
ATOM 6989 C CB  . LYS E 5 19  ? 152.359 161.941 147.747 1.00 86.65  ? 19  LYS S CB  1 
ATOM 6990 C CG  . LYS E 5 19  ? 151.623 160.686 147.316 1.00 85.44  ? 19  LYS S CG  1 
ATOM 6991 C CD  . LYS E 5 19  ? 152.286 160.060 146.100 1.00 85.71  ? 19  LYS S CD  1 
ATOM 6992 C CE  . LYS E 5 19  ? 151.341 159.120 145.373 1.00 86.87  ? 19  LYS S CE  1 
ATOM 6993 N NZ  . LYS E 5 19  ? 151.988 158.496 144.186 1.00 88.25  ? 19  LYS S NZ  1 
ATOM 6994 N N   . LEU E 5 20  ? 150.490 161.568 150.513 1.00 84.69  ? 20  LEU S N   1 
ATOM 6995 C CA  . LEU E 5 20  ? 150.365 160.862 151.779 1.00 80.05  ? 20  LEU S CA  1 
ATOM 6996 C C   . LEU E 5 20  ? 150.176 159.376 151.515 1.00 79.07  ? 20  LEU S C   1 
ATOM 6997 O O   . LEU E 5 20  ? 149.377 158.987 150.658 1.00 76.16  ? 20  LEU S O   1 
ATOM 6998 C CB  . LEU E 5 20  ? 149.190 161.399 152.600 1.00 76.03  ? 20  LEU S CB  1 
ATOM 6999 C CG  . LEU E 5 20  ? 149.093 162.914 152.780 1.00 77.62  ? 20  LEU S CG  1 
ATOM 7000 C CD1 . LEU E 5 20  ? 147.973 163.259 153.745 1.00 79.38  ? 20  LEU S CD1 1 
ATOM 7001 C CD2 . LEU E 5 20  ? 150.412 163.491 153.263 1.00 80.34  ? 20  LEU S CD2 1 
ATOM 7002 N N   . SER E 5 21  ? 150.909 158.548 152.253 1.00 84.96  ? 21  SER S N   1 
ATOM 7003 C CA  . SER E 5 21  ? 150.873 157.102 152.085 1.00 87.74  ? 21  SER S CA  1 
ATOM 7004 C C   . SER E 5 21  ? 150.288 156.461 153.334 1.00 85.97  ? 21  SER S C   1 
ATOM 7005 O O   . SER E 5 21  ? 150.780 156.694 154.441 1.00 82.68  ? 21  SER S O   1 
ATOM 7006 C CB  . SER E 5 21  ? 152.273 156.545 151.814 1.00 88.68  ? 21  SER S CB  1 
ATOM 7007 O OG  . SER E 5 21  ? 152.740 156.931 150.534 1.00 91.23  ? 21  SER S OG  1 
ATOM 7008 N N   . CYS E 5 22  ? 149.249 155.647 153.152 1.00 78.09  ? 22  CYS S N   1 
ATOM 7009 C CA  . CYS E 5 22  ? 148.599 154.922 154.243 1.00 73.75  ? 22  CYS S CA  1 
ATOM 7010 C C   . CYS E 5 22  ? 148.974 153.450 154.106 1.00 75.81  ? 22  CYS S C   1 
ATOM 7011 O O   . CYS E 5 22  ? 148.416 152.733 153.271 1.00 74.20  ? 22  CYS S O   1 
ATOM 7012 C CB  . CYS E 5 22  ? 147.084 155.121 154.210 1.00 81.33  ? 22  CYS S CB  1 
ATOM 7013 S SG  . CYS E 5 22  ? 146.143 154.007 155.293 1.00 98.12  ? 22  CYS S SG  1 
ATOM 7014 N N   . SER E 5 23  ? 149.923 153.006 154.926 1.00 76.07  ? 23  SER S N   1 
ATOM 7015 C CA  . SER E 5 23  ? 150.405 151.632 154.886 1.00 74.37  ? 23  SER S CA  1 
ATOM 7016 C C   . SER E 5 23  ? 149.589 150.769 155.839 1.00 76.29  ? 23  SER S C   1 
ATOM 7017 O O   . SER E 5 23  ? 149.410 151.124 157.008 1.00 80.17  ? 23  SER S O   1 
ATOM 7018 C CB  . SER E 5 23  ? 151.887 151.569 155.254 1.00 75.48  ? 23  SER S CB  1 
ATOM 7019 O OG  . SER E 5 23  ? 152.155 152.330 156.418 1.00 78.85  ? 23  SER S OG  1 
ATOM 7020 N N   . ALA E 5 24  ? 149.103 149.638 155.338 1.00 70.51  ? 24  ALA S N   1 
ATOM 7021 C CA  . ALA E 5 24  ? 148.254 148.736 156.100 1.00 66.18  ? 24  ALA S CA  1 
ATOM 7022 C C   . ALA E 5 24  ? 148.972 147.417 156.344 1.00 67.76  ? 24  ALA S C   1 
ATOM 7023 O O   . ALA E 5 24  ? 149.699 146.925 155.475 1.00 72.39  ? 24  ALA S O   1 
ATOM 7024 C CB  . ALA E 5 24  ? 146.937 148.478 155.373 1.00 68.96  ? 24  ALA S CB  1 
ATOM 7025 N N   . SER E 5 25  ? 148.761 146.848 157.529 1.00 70.79  ? 25  SER S N   1 
ATOM 7026 C CA  . SER E 5 25  ? 149.393 145.580 157.886 1.00 76.17  ? 25  SER S CA  1 
ATOM 7027 C C   . SER E 5 25  ? 148.546 144.916 158.961 1.00 76.08  ? 25  SER S C   1 
ATOM 7028 O O   . SER E 5 25  ? 148.470 145.420 160.085 1.00 80.98  ? 25  SER S O   1 
ATOM 7029 C CB  . SER E 5 25  ? 150.821 145.805 158.370 1.00 77.20  ? 25  SER S CB  1 
ATOM 7030 O OG  . SER E 5 25  ? 150.837 146.532 159.586 1.00 76.38  ? 25  SER S OG  1 
ATOM 7031 N N   . GLY E 5 26  ? 147.916 143.795 158.619 1.00 66.04  ? 26  GLY S N   1 
ATOM 7032 C CA  . GLY E 5 26  ? 147.137 143.055 159.591 1.00 70.76  ? 26  GLY S CA  1 
ATOM 7033 C C   . GLY E 5 26  ? 145.773 142.620 159.100 1.00 70.02  ? 26  GLY S C   1 
ATOM 7034 O O   . GLY E 5 26  ? 144.980 142.075 159.872 1.00 73.16  ? 26  GLY S O   1 
ATOM 7035 N N   . PHE E 5 27  ? 145.481 142.858 157.824 1.00 59.86  ? 27  PHE S N   1 
ATOM 7036 C CA  . PHE E 5 27  ? 144.206 142.454 157.248 1.00 62.90  ? 27  PHE S CA  1 
ATOM 7037 C C   . PHE E 5 27  ? 144.364 142.345 155.738 1.00 63.22  ? 27  PHE S C   1 
ATOM 7038 O O   . PHE E 5 27  ? 145.357 142.794 155.162 1.00 61.83  ? 27  PHE S O   1 
ATOM 7039 C CB  . PHE E 5 27  ? 143.083 143.429 157.621 1.00 65.88  ? 27  PHE S CB  1 
ATOM 7040 C CG  . PHE E 5 27  ? 143.302 144.834 157.131 1.00 62.75  ? 27  PHE S CG  1 
ATOM 7041 C CD1 . PHE E 5 27  ? 143.976 145.756 157.911 1.00 60.33  ? 27  PHE S CD1 1 
ATOM 7042 C CD2 . PHE E 5 27  ? 142.822 145.235 155.896 1.00 60.78  ? 27  PHE S CD2 1 
ATOM 7043 C CE1 . PHE E 5 27  ? 144.174 147.046 157.467 1.00 58.72  ? 27  PHE S CE1 1 
ATOM 7044 C CE2 . PHE E 5 27  ? 143.020 146.524 155.448 1.00 58.32  ? 27  PHE S CE2 1 
ATOM 7045 C CZ  . PHE E 5 27  ? 143.694 147.430 156.235 1.00 56.98  ? 27  PHE S CZ  1 
ATOM 7046 N N   . ALA E 5 28  ? 143.364 141.733 155.104 1.00 57.20  ? 28  ALA S N   1 
ATOM 7047 C CA  . ALA E 5 28  ? 143.359 141.585 153.655 1.00 58.25  ? 28  ALA S CA  1 
ATOM 7048 C C   . ALA E 5 28  ? 143.073 142.924 152.990 1.00 54.47  ? 28  ALA S C   1 
ATOM 7049 O O   . ALA E 5 28  ? 141.911 143.296 152.808 1.00 63.67  ? 28  ALA S O   1 
ATOM 7050 C CB  . ALA E 5 28  ? 142.328 140.542 153.223 1.00 59.13  ? 28  ALA S CB  1 
ATOM 7051 N N   . PHE E 5 29  ? 144.131 143.646 152.616 1.00 55.58  ? 29  PHE S N   1 
ATOM 7052 C CA  . PHE E 5 29  ? 143.967 145.003 152.103 1.00 60.96  ? 29  PHE S CA  1 
ATOM 7053 C C   . PHE E 5 29  ? 143.153 145.026 150.816 1.00 56.71  ? 29  PHE S C   1 
ATOM 7054 O O   . PHE E 5 29  ? 142.350 145.939 150.600 1.00 59.09  ? 29  PHE S O   1 
ATOM 7055 C CB  . PHE E 5 29  ? 145.338 145.642 151.886 1.00 68.99  ? 29  PHE S CB  1 
ATOM 7056 C CG  . PHE E 5 29  ? 145.281 147.081 151.463 1.00 61.21  ? 29  PHE S CG  1 
ATOM 7057 C CD1 . PHE E 5 29  ? 145.253 148.090 152.406 1.00 58.02  ? 29  PHE S CD1 1 
ATOM 7058 C CD2 . PHE E 5 29  ? 145.284 147.425 150.124 1.00 65.49  ? 29  PHE S CD2 1 
ATOM 7059 C CE1 . PHE E 5 29  ? 145.210 149.413 152.022 1.00 63.16  ? 29  PHE S CE1 1 
ATOM 7060 C CE2 . PHE E 5 29  ? 145.241 148.745 149.735 1.00 66.22  ? 29  PHE S CE2 1 
ATOM 7061 C CZ  . PHE E 5 29  ? 145.204 149.741 150.685 1.00 65.16  ? 29  PHE S CZ  1 
ATOM 7062 N N   . SER E 5 30  ? 143.342 144.030 149.951 1.00 60.67  ? 30  SER S N   1 
ATOM 7063 C CA  . SER E 5 30  ? 142.693 144.036 148.646 1.00 70.85  ? 30  SER S CA  1 
ATOM 7064 C C   . SER E 5 30  ? 141.177 143.909 148.728 1.00 70.50  ? 30  SER S C   1 
ATOM 7065 O O   . SER E 5 30  ? 140.501 144.166 147.727 1.00 69.91  ? 30  SER S O   1 
ATOM 7066 C CB  . SER E 5 30  ? 143.253 142.908 147.779 1.00 68.10  ? 30  SER S CB  1 
ATOM 7067 O OG  . SER E 5 30  ? 144.587 143.178 147.388 1.00 69.21  ? 30  SER S OG  1 
ATOM 7068 N N   . SER E 5 31  ? 140.631 143.521 149.877 1.00 58.61  ? 31  SER S N   1 
ATOM 7069 C CA  . SER E 5 31  ? 139.200 143.305 150.028 1.00 57.11  ? 31  SER S CA  1 
ATOM 7070 C C   . SER E 5 31  ? 138.493 144.429 150.774 1.00 63.00  ? 31  SER S C   1 
ATOM 7071 O O   . SER E 5 31  ? 137.297 144.306 151.055 1.00 68.90  ? 31  SER S O   1 
ATOM 7072 C CB  . SER E 5 31  ? 138.945 141.975 150.744 1.00 56.43  ? 31  SER S CB  1 
ATOM 7073 O OG  . SER E 5 31  ? 137.559 141.757 150.932 1.00 66.44  ? 31  SER S OG  1 
ATOM 7074 N N   . PHE E 5 32  ? 139.190 145.514 151.098 1.00 54.84  ? 32  PHE S N   1 
ATOM 7075 C CA  . PHE E 5 32  ? 138.633 146.601 151.891 1.00 47.02  ? 32  PHE S CA  1 
ATOM 7076 C C   . PHE E 5 32  ? 138.618 147.886 151.079 1.00 52.87  ? 32  PHE S C   1 
ATOM 7077 O O   . PHE E 5 32  ? 139.647 148.286 150.527 1.00 65.14  ? 32  PHE S O   1 
ATOM 7078 C CB  . PHE E 5 32  ? 139.440 146.815 153.173 1.00 41.03  ? 32  PHE S CB  1 
ATOM 7079 C CG  . PHE E 5 32  ? 139.081 145.872 154.278 1.00 44.13  ? 32  PHE S CG  1 
ATOM 7080 C CD1 . PHE E 5 32  ? 139.592 144.590 154.305 1.00 51.34  ? 32  PHE S CD1 1 
ATOM 7081 C CD2 . PHE E 5 32  ? 138.239 146.271 155.295 1.00 56.47  ? 32  PHE S CD2 1 
ATOM 7082 C CE1 . PHE E 5 32  ? 139.265 143.722 155.322 1.00 50.59  ? 32  PHE S CE1 1 
ATOM 7083 C CE2 . PHE E 5 32  ? 137.910 145.407 156.311 1.00 59.13  ? 32  PHE S CE2 1 
ATOM 7084 C CZ  . PHE E 5 32  ? 138.424 144.132 156.326 1.00 51.04  ? 32  PHE S CZ  1 
ATOM 7085 N N   . GLY E 5 33  ? 137.457 148.534 151.016 1.00 48.57  ? 33  GLY S N   1 
ATOM 7086 C CA  . GLY E 5 33  ? 137.385 149.875 150.462 1.00 42.12  ? 33  GLY S CA  1 
ATOM 7087 C C   . GLY E 5 33  ? 137.940 150.862 151.469 1.00 41.16  ? 33  GLY S C   1 
ATOM 7088 O O   . GLY E 5 33  ? 137.597 150.815 152.654 1.00 58.13  ? 33  GLY S O   1 
ATOM 7089 N N   . MET E 5 34  ? 138.806 151.755 151.005 1.00 40.82  ? 34  MET S N   1 
ATOM 7090 C CA  . MET E 5 34  ? 139.532 152.659 151.882 1.00 45.73  ? 34  MET S CA  1 
ATOM 7091 C C   . MET E 5 34  ? 139.095 154.098 151.650 1.00 48.80  ? 34  MET S C   1 
ATOM 7092 O O   . MET E 5 34  ? 138.849 154.507 150.512 1.00 56.00  ? 34  MET S O   1 
ATOM 7093 C CB  . MET E 5 34  ? 141.040 152.528 151.669 1.00 46.07  ? 34  MET S CB  1 
ATOM 7094 C CG  . MET E 5 34  ? 141.538 151.097 151.730 1.00 49.36  ? 34  MET S CG  1 
ATOM 7095 S SD  . MET E 5 34  ? 141.599 150.453 153.411 1.00 67.10  ? 34  MET S SD  1 
ATOM 7096 C CE  . MET E 5 34  ? 142.805 151.550 154.148 1.00 51.67  ? 34  MET S CE  1 
ATOM 7097 N N   . HIS E 5 35  ? 139.002 154.858 152.735 1.00 57.53  ? 35  HIS S N   1 
ATOM 7098 C CA  . HIS E 5 35  ? 138.598 156.254 152.707 1.00 55.96  ? 35  HIS S CA  1 
ATOM 7099 C C   . HIS E 5 35  ? 139.746 157.151 153.151 1.00 59.78  ? 35  HIS S C   1 
ATOM 7100 O O   . HIS E 5 35  ? 140.811 156.690 153.567 1.00 68.38  ? 35  HIS S O   1 
ATOM 7101 C CB  . HIS E 5 35  ? 137.384 156.493 153.612 1.00 59.08  ? 35  HIS S CB  1 
ATOM 7102 C CG  . HIS E 5 35  ? 136.148 155.768 153.183 1.00 61.94  ? 35  HIS S CG  1 
ATOM 7103 N ND1 . HIS E 5 35  ? 135.067 156.410 152.618 1.00 67.69  ? 35  HIS S ND1 1 
ATOM 7104 C CD2 . HIS E 5 35  ? 135.814 154.459 153.249 1.00 64.17  ? 35  HIS S CD2 1 
ATOM 7105 C CE1 . HIS E 5 35  ? 134.124 155.526 152.349 1.00 61.05  ? 35  HIS S CE1 1 
ATOM 7106 N NE2 . HIS E 5 35  ? 134.553 154.334 152.721 1.00 59.58  ? 35  HIS S NE2 1 
ATOM 7107 N N   . TRP E 5 36  ? 139.506 158.455 153.047 1.00 33.02  ? 36  TRP S N   1 
ATOM 7108 C CA  . TRP E 5 36  ? 140.356 159.478 153.644 1.00 30.61  ? 36  TRP S CA  1 
ATOM 7109 C C   . TRP E 5 36  ? 139.447 160.487 154.324 1.00 46.04  ? 36  TRP S C   1 
ATOM 7110 O O   . TRP E 5 36  ? 138.558 161.053 153.681 1.00 57.46  ? 36  TRP S O   1 
ATOM 7111 C CB  . TRP E 5 36  ? 141.235 160.169 152.598 1.00 42.08  ? 36  TRP S CB  1 
ATOM 7112 C CG  . TRP E 5 36  ? 142.519 159.459 152.291 1.00 42.74  ? 36  TRP S CG  1 
ATOM 7113 C CD1 . TRP E 5 36  ? 142.786 158.685 151.203 1.00 48.28  ? 36  TRP S CD1 1 
ATOM 7114 C CD2 . TRP E 5 36  ? 143.720 159.479 153.072 1.00 42.05  ? 36  TRP S CD2 1 
ATOM 7115 N NE1 . TRP E 5 36  ? 144.073 158.211 151.262 1.00 48.65  ? 36  TRP S NE1 1 
ATOM 7116 C CE2 . TRP E 5 36  ? 144.668 158.684 152.401 1.00 39.52  ? 36  TRP S CE2 1 
ATOM 7117 C CE3 . TRP E 5 36  ? 144.083 160.086 154.277 1.00 47.38  ? 36  TRP S CE3 1 
ATOM 7118 C CZ2 . TRP E 5 36  ? 145.953 158.481 152.893 1.00 35.11  ? 36  TRP S CZ2 1 
ATOM 7119 C CZ3 . TRP E 5 36  ? 145.360 159.882 154.763 1.00 46.27  ? 36  TRP S CZ3 1 
ATOM 7120 C CH2 . TRP E 5 36  ? 146.279 159.087 154.072 1.00 38.12  ? 36  TRP S CH2 1 
ATOM 7121 N N   . VAL E 5 37  ? 139.659 160.705 155.618 1.00 57.73  ? 37  VAL S N   1 
ATOM 7122 C CA  . VAL E 5 37  ? 138.860 161.637 156.402 1.00 53.46  ? 37  VAL S CA  1 
ATOM 7123 C C   . VAL E 5 37  ? 139.805 162.620 157.074 1.00 55.73  ? 37  VAL S C   1 
ATOM 7124 O O   . VAL E 5 37  ? 140.761 162.209 157.740 1.00 58.68  ? 37  VAL S O   1 
ATOM 7125 C CB  . VAL E 5 37  ? 137.994 160.913 157.450 1.00 48.45  ? 37  VAL S CB  1 
ATOM 7126 C CG1 . VAL E 5 37  ? 137.185 161.915 158.250 1.00 53.06  ? 37  VAL S CG1 1 
ATOM 7127 C CG2 . VAL E 5 37  ? 137.081 159.899 156.780 1.00 48.51  ? 37  VAL S CG2 1 
ATOM 7128 N N   . ARG E 5 38  ? 139.539 163.911 156.904 1.00 57.05  ? 38  ARG S N   1 
ATOM 7129 C CA  . ARG E 5 38  ? 140.371 164.963 157.466 1.00 53.99  ? 38  ARG S CA  1 
ATOM 7130 C C   . ARG E 5 38  ? 139.607 165.696 158.558 1.00 53.56  ? 38  ARG S C   1 
ATOM 7131 O O   . ARG E 5 38  ? 138.387 165.864 158.472 1.00 65.59  ? 38  ARG S O   1 
ATOM 7132 C CB  . ARG E 5 38  ? 140.824 165.950 156.385 1.00 60.14  ? 38  ARG S CB  1 
ATOM 7133 C CG  . ARG E 5 38  ? 139.748 166.904 155.894 1.00 58.87  ? 38  ARG S CG  1 
ATOM 7134 C CD  . ARG E 5 38  ? 140.317 168.289 155.640 1.00 62.48  ? 38  ARG S CD  1 
ATOM 7135 N NE  . ARG E 5 38  ? 139.383 169.145 154.919 1.00 62.98  ? 38  ARG S NE  1 
ATOM 7136 C CZ  . ARG E 5 38  ? 139.215 169.129 153.604 1.00 67.44  ? 38  ARG S CZ  1 
ATOM 7137 N NH1 . ARG E 5 38  ? 139.906 168.310 152.829 1.00 65.08  ? 38  ARG S NH1 1 
ATOM 7138 N NH2 . ARG E 5 38  ? 138.333 169.958 153.053 1.00 68.37  ? 38  ARG S NH2 1 
ATOM 7139 N N   . GLN E 5 39  ? 140.328 166.114 159.594 1.00 57.52  ? 39  GLN S N   1 
ATOM 7140 C CA  . GLN E 5 39  ? 139.745 166.840 160.717 1.00 62.96  ? 39  GLN S CA  1 
ATOM 7141 C C   . GLN E 5 39  ? 140.499 168.150 160.880 1.00 66.41  ? 39  GLN S C   1 
ATOM 7142 O O   . GLN E 5 39  ? 141.681 168.150 161.240 1.00 75.68  ? 39  GLN S O   1 
ATOM 7143 C CB  . GLN E 5 39  ? 139.801 166.013 162.001 1.00 68.02  ? 39  GLN S CB  1 
ATOM 7144 C CG  . GLN E 5 39  ? 139.569 166.821 163.265 1.00 69.11  ? 39  GLN S CG  1 
ATOM 7145 C CD  . GLN E 5 39  ? 139.232 165.953 164.458 1.00 66.73  ? 39  GLN S CD  1 
ATOM 7146 O OE1 . GLN E 5 39  ? 139.175 164.729 164.353 1.00 67.97  ? 39  GLN S OE1 1 
ATOM 7147 N NE2 . GLN E 5 39  ? 139.008 166.584 165.604 1.00 67.28  ? 39  GLN S NE2 1 
ATOM 7148 N N   . ALA E 5 40  ? 139.819 169.261 160.618 1.00 73.00  ? 40  ALA S N   1 
ATOM 7149 C CA  . ALA E 5 40  ? 140.421 170.565 160.800 1.00 76.10  ? 40  ALA S CA  1 
ATOM 7150 C C   . ALA E 5 40  ? 140.676 170.817 162.283 1.00 80.92  ? 40  ALA S C   1 
ATOM 7151 O O   . ALA E 5 40  ? 140.022 170.222 163.142 1.00 88.55  ? 40  ALA S O   1 
ATOM 7152 C CB  . ALA E 5 40  ? 139.516 171.648 160.221 1.00 83.22  ? 40  ALA S CB  1 
ATOM 7153 N N   . PRO E 5 41  ? 141.642 171.676 162.609 1.00 97.33  ? 41  PRO S N   1 
ATOM 7154 C CA  . PRO E 5 41  ? 141.932 171.963 164.023 1.00 99.86  ? 41  PRO S CA  1 
ATOM 7155 C C   . PRO E 5 41  ? 140.699 172.468 164.758 1.00 104.27 ? 41  PRO S C   1 
ATOM 7156 O O   . PRO E 5 41  ? 140.107 173.485 164.390 1.00 103.78 ? 41  PRO S O   1 
ATOM 7157 C CB  . PRO E 5 41  ? 143.026 173.033 163.946 1.00 99.16  ? 41  PRO S CB  1 
ATOM 7158 C CG  . PRO E 5 41  ? 143.698 172.780 162.643 1.00 100.52 ? 41  PRO S CG  1 
ATOM 7159 C CD  . PRO E 5 41  ? 142.622 172.307 161.707 1.00 97.39  ? 41  PRO S CD  1 
ATOM 7160 N N   . GLU E 5 42  ? 140.312 171.725 165.802 1.00 113.44 ? 42  GLU S N   1 
ATOM 7161 C CA  . GLU E 5 42  ? 139.190 172.053 166.693 1.00 111.52 ? 42  GLU S CA  1 
ATOM 7162 C C   . GLU E 5 42  ? 137.941 172.493 165.926 1.00 111.19 ? 42  GLU S C   1 
ATOM 7163 O O   . GLU E 5 42  ? 137.181 173.355 166.371 1.00 114.72 ? 42  GLU S O   1 
ATOM 7164 C CB  . GLU E 5 42  ? 139.601 173.096 167.743 1.00 109.08 ? 42  GLU S CB  1 
ATOM 7165 C CG  . GLU E 5 42  ? 139.864 174.511 167.241 1.00 111.22 ? 42  GLU S CG  1 
ATOM 7166 C CD  . GLU E 5 42  ? 141.338 174.786 167.024 1.00 111.66 ? 42  GLU S CD  1 
ATOM 7167 O OE1 . GLU E 5 42  ? 142.167 173.951 167.445 1.00 111.21 ? 42  GLU S OE1 1 
ATOM 7168 O OE2 . GLU E 5 42  ? 141.670 175.834 166.432 1.00 111.51 ? 42  GLU S OE2 1 
ATOM 7169 N N   . LYS E 5 43  ? 137.710 171.876 164.768 1.00 102.76 ? 43  LYS S N   1 
ATOM 7170 C CA  . LYS E 5 43  ? 136.504 172.143 163.992 1.00 104.02 ? 43  LYS S CA  1 
ATOM 7171 C C   . LYS E 5 43  ? 135.646 170.905 163.787 1.00 107.89 ? 43  LYS S C   1 
ATOM 7172 O O   . LYS E 5 43  ? 134.425 170.969 163.973 1.00 114.99 ? 43  LYS S O   1 
ATOM 7173 C CB  . LYS E 5 43  ? 136.865 172.768 162.634 1.00 103.15 ? 43  LYS S CB  1 
ATOM 7174 C CG  . LYS E 5 43  ? 137.062 174.275 162.696 1.00 106.23 ? 43  LYS S CG  1 
ATOM 7175 C CD  . LYS E 5 43  ? 136.883 174.924 161.333 1.00 109.54 ? 43  LYS S CD  1 
ATOM 7176 C CE  . LYS E 5 43  ? 138.178 174.941 160.543 1.00 108.65 ? 43  LYS S CE  1 
ATOM 7177 N NZ  . LYS E 5 43  ? 138.024 175.660 159.249 1.00 105.04 ? 43  LYS S NZ  1 
ATOM 7178 N N   . GLY E 5 44  ? 136.241 169.776 163.409 1.00 82.85  ? 44  GLY S N   1 
ATOM 7179 C CA  . GLY E 5 44  ? 135.468 168.562 163.231 1.00 82.58  ? 44  GLY S CA  1 
ATOM 7180 C C   . GLY E 5 44  ? 135.845 167.753 162.006 1.00 87.32  ? 44  GLY S C   1 
ATOM 7181 O O   . GLY E 5 44  ? 136.587 168.227 161.141 1.00 90.17  ? 44  GLY S O   1 
ATOM 7182 N N   . LEU E 5 45  ? 135.331 166.528 161.925 1.00 68.57  ? 45  LEU S N   1 
ATOM 7183 C CA  . LEU E 5 45  ? 135.673 165.632 160.832 1.00 61.66  ? 45  LEU S CA  1 
ATOM 7184 C C   . LEU E 5 45  ? 134.994 166.068 159.537 1.00 62.19  ? 45  LEU S C   1 
ATOM 7185 O O   . LEU E 5 45  ? 133.984 166.778 159.537 1.00 60.86  ? 45  LEU S O   1 
ATOM 7186 C CB  . LEU E 5 45  ? 135.274 164.197 161.174 1.00 58.62  ? 45  LEU S CB  1 
ATOM 7187 C CG  . LEU E 5 45  ? 136.042 163.530 162.317 1.00 54.86  ? 45  LEU S CG  1 
ATOM 7188 C CD1 . LEU E 5 45  ? 135.300 162.303 162.817 1.00 59.01  ? 45  LEU S CD1 1 
ATOM 7189 C CD2 . LEU E 5 45  ? 137.446 163.164 161.879 1.00 59.46  ? 45  LEU S CD2 1 
ATOM 7190 N N   . GLU E 5 46  ? 135.570 165.631 158.418 1.00 55.79  ? 46  GLU S N   1 
ATOM 7191 C CA  . GLU E 5 46  ? 135.026 165.938 157.102 1.00 53.55  ? 46  GLU S CA  1 
ATOM 7192 C C   . GLU E 5 46  ? 135.550 164.912 156.110 1.00 57.10  ? 46  GLU S C   1 
ATOM 7193 O O   . GLU E 5 46  ? 136.751 164.632 156.087 1.00 71.09  ? 46  GLU S O   1 
ATOM 7194 C CB  . GLU E 5 46  ? 135.409 167.356 156.664 1.00 54.87  ? 46  GLU S CB  1 
ATOM 7195 C CG  . GLU E 5 46  ? 135.032 167.690 155.232 1.00 60.48  ? 46  GLU S CG  1 
ATOM 7196 C CD  . GLU E 5 46  ? 135.095 169.177 154.946 1.00 63.27  ? 46  GLU S CD  1 
ATOM 7197 O OE1 . GLU E 5 46  ? 135.559 169.934 155.825 1.00 66.11  ? 46  GLU S OE1 1 
ATOM 7198 O OE2 . GLU E 5 46  ? 134.681 169.590 153.843 1.00 60.10  ? 46  GLU S OE2 1 
ATOM 7199 N N   . TRP E 5 47  ? 134.653 164.358 155.300 1.00 38.93  ? 47  TRP S N   1 
ATOM 7200 C CA  . TRP E 5 47  ? 135.024 163.337 154.332 1.00 42.91  ? 47  TRP S CA  1 
ATOM 7201 C C   . TRP E 5 47  ? 135.775 163.955 153.158 1.00 52.99  ? 47  TRP S C   1 
ATOM 7202 O O   . TRP E 5 47  ? 135.514 165.093 152.758 1.00 59.74  ? 47  TRP S O   1 
ATOM 7203 C CB  . TRP E 5 47  ? 133.779 162.602 153.840 1.00 34.86  ? 47  TRP S CB  1 
ATOM 7204 C CG  . TRP E 5 47  ? 134.058 161.495 152.882 1.00 34.48  ? 47  TRP S CG  1 
ATOM 7205 C CD1 . TRP E 5 47  ? 134.678 160.314 153.154 1.00 37.70  ? 47  TRP S CD1 1 
ATOM 7206 C CD2 . TRP E 5 47  ? 133.702 161.452 151.496 1.00 46.62  ? 47  TRP S CD2 1 
ATOM 7207 N NE1 . TRP E 5 47  ? 134.743 159.542 152.021 1.00 46.13  ? 47  TRP S NE1 1 
ATOM 7208 C CE2 . TRP E 5 47  ? 134.149 160.218 150.989 1.00 45.23  ? 47  TRP S CE2 1 
ATOM 7209 C CE3 . TRP E 5 47  ? 133.053 162.340 150.634 1.00 51.53  ? 47  TRP S CE3 1 
ATOM 7210 C CZ2 . TRP E 5 47  ? 133.968 159.850 149.660 1.00 45.04  ? 47  TRP S CZ2 1 
ATOM 7211 C CZ3 . TRP E 5 47  ? 132.875 161.972 149.315 1.00 50.48  ? 47  TRP S CZ3 1 
ATOM 7212 C CH2 . TRP E 5 47  ? 133.331 160.738 148.841 1.00 50.36  ? 47  TRP S CH2 1 
ATOM 7213 N N   . VAL E 5 48  ? 136.722 163.193 152.608 1.00 57.18  ? 48  VAL S N   1 
ATOM 7214 C CA  . VAL E 5 48  ? 137.589 163.700 151.547 1.00 52.16  ? 48  VAL S CA  1 
ATOM 7215 C C   . VAL E 5 48  ? 137.490 162.840 150.293 1.00 50.15  ? 48  VAL S C   1 
ATOM 7216 O O   . VAL E 5 48  ? 137.096 163.327 149.228 1.00 54.63  ? 48  VAL S O   1 
ATOM 7217 C CB  . VAL E 5 48  ? 139.048 163.792 152.026 1.00 47.13  ? 48  VAL S CB  1 
ATOM 7218 C CG1 . VAL E 5 48  ? 139.981 164.012 150.846 1.00 54.63  ? 48  VAL S CG1 1 
ATOM 7219 C CG2 . VAL E 5 48  ? 139.199 164.908 153.037 1.00 42.59  ? 48  VAL S CG2 1 
ATOM 7220 N N   . ALA E 5 49  ? 137.850 161.562 150.401 1.00 50.98  ? 49  ALA S N   1 
ATOM 7221 C CA  . ALA E 5 49  ? 137.923 160.702 149.227 1.00 51.78  ? 49  ALA S CA  1 
ATOM 7222 C C   . ALA E 5 49  ? 137.647 159.260 149.624 1.00 54.39  ? 49  ALA S C   1 
ATOM 7223 O O   . ALA E 5 49  ? 137.743 158.887 150.795 1.00 71.70  ? 49  ALA S O   1 
ATOM 7224 C CB  . ALA E 5 49  ? 139.286 160.812 148.537 1.00 54.70  ? 49  ALA S CB  1 
ATOM 7225 N N   . TYR E 5 50  ? 137.303 158.449 148.625 1.00 41.26  ? 50  TYR S N   1 
ATOM 7226 C CA  . TYR E 5 50  ? 137.012 157.038 148.834 1.00 48.71  ? 50  TYR S CA  1 
ATOM 7227 C C   . TYR E 5 50  ? 137.347 156.261 147.571 1.00 54.30  ? 50  TYR S C   1 
ATOM 7228 O O   . TYR E 5 50  ? 137.007 156.689 146.465 1.00 65.40  ? 50  TYR S O   1 
ATOM 7229 C CB  . TYR E 5 50  ? 135.543 156.820 149.209 1.00 47.90  ? 50  TYR S CB  1 
ATOM 7230 C CG  . TYR E 5 50  ? 134.991 155.470 148.809 1.00 48.22  ? 50  TYR S CG  1 
ATOM 7231 C CD1 . TYR E 5 50  ? 135.379 154.314 149.470 1.00 54.20  ? 50  TYR S CD1 1 
ATOM 7232 C CD2 . TYR E 5 50  ? 134.075 155.353 147.774 1.00 52.79  ? 50  TYR S CD2 1 
ATOM 7233 C CE1 . TYR E 5 50  ? 134.875 153.082 149.109 1.00 52.18  ? 50  TYR S CE1 1 
ATOM 7234 C CE2 . TYR E 5 50  ? 133.566 154.125 147.407 1.00 52.81  ? 50  TYR S CE2 1 
ATOM 7235 C CZ  . TYR E 5 50  ? 133.969 152.993 148.078 1.00 50.02  ? 50  TYR S CZ  1 
ATOM 7236 O OH  . TYR E 5 50  ? 133.465 151.766 147.717 1.00 46.07  ? 50  TYR S OH  1 
ATOM 7237 N N   . ILE E 5 51  ? 138.008 155.118 147.743 1.00 61.15  ? 51  ILE S N   1 
ATOM 7238 C CA  . ILE E 5 51  ? 138.341 154.219 146.644 1.00 60.38  ? 51  ILE S CA  1 
ATOM 7239 C C   . ILE E 5 51  ? 137.846 152.823 147.001 1.00 60.57  ? 51  ILE S C   1 
ATOM 7240 O O   . ILE E 5 51  ? 138.080 152.342 148.114 1.00 71.71  ? 51  ILE S O   1 
ATOM 7241 C CB  . ILE E 5 51  ? 139.853 154.211 146.347 1.00 56.25  ? 51  ILE S CB  1 
ATOM 7242 C CG1 . ILE E 5 51  ? 140.193 153.127 145.324 1.00 63.01  ? 51  ILE S CG1 1 
ATOM 7243 C CG2 . ILE E 5 51  ? 140.655 154.032 147.623 1.00 62.47  ? 51  ILE S CG2 1 
ATOM 7244 C CD1 . ILE E 5 51  ? 141.460 153.403 144.552 1.00 69.98  ? 51  ILE S CD1 1 
ATOM 7245 N N   . SER E 5 52  ? 137.155 152.181 146.064 1.00 50.73  ? 52  SER S N   1 
ATOM 7246 C CA  . SER E 5 52  ? 136.520 150.896 146.323 1.00 55.02  ? 52  SER S CA  1 
ATOM 7247 C C   . SER E 5 52  ? 137.562 149.780 146.286 1.00 58.79  ? 52  SER S C   1 
ATOM 7248 O O   . SER E 5 52  ? 138.769 150.021 146.200 1.00 63.88  ? 52  SER S O   1 
ATOM 7249 C CB  . SER E 5 52  ? 135.395 150.652 145.322 1.00 58.64  ? 52  SER S CB  1 
ATOM 7250 O OG  . SER E 5 52  ? 135.909 150.439 144.020 1.00 60.56  ? 52  SER S OG  1 
ATOM 7251 N N   . SER E 5 53  ? 137.098 148.535 146.359 1.00 65.68  ? 53  SER S N   1 
ATOM 7252 C CA  . SER E 5 53  ? 137.985 147.385 146.265 1.00 66.66  ? 53  SER S CA  1 
ATOM 7253 C C   . SER E 5 53  ? 138.372 147.152 144.811 1.00 69.70  ? 53  SER S C   1 
ATOM 7254 O O   . SER E 5 53  ? 137.509 147.090 143.931 1.00 67.18  ? 53  SER S O   1 
ATOM 7255 C CB  . SER E 5 53  ? 137.313 146.140 146.841 1.00 72.04  ? 53  SER S CB  1 
ATOM 7256 O OG  . SER E 5 53  ? 136.274 145.684 145.994 1.00 77.11  ? 53  SER S OG  1 
ATOM 7257 N N   . GLY E 5 54  ? 139.672 147.016 144.562 1.00 76.59  ? 54  GLY S N   1 
ATOM 7258 C CA  . GLY E 5 54  ? 140.151 146.867 143.204 1.00 76.93  ? 54  GLY S CA  1 
ATOM 7259 C C   . GLY E 5 54  ? 140.200 148.148 142.409 1.00 75.62  ? 54  GLY S C   1 
ATOM 7260 O O   . GLY E 5 54  ? 140.313 148.095 141.180 1.00 79.84  ? 54  GLY S O   1 
ATOM 7261 N N   . SER E 5 55  ? 140.111 149.302 143.074 1.00 67.93  ? 55  SER S N   1 
ATOM 7262 C CA  . SER E 5 55  ? 140.159 150.611 142.421 1.00 66.83  ? 55  SER S CA  1 
ATOM 7263 C C   . SER E 5 55  ? 139.069 150.761 141.363 1.00 66.95  ? 55  SER S C   1 
ATOM 7264 O O   . SER E 5 55  ? 139.273 151.408 140.335 1.00 69.07  ? 55  SER S O   1 
ATOM 7265 C CB  . SER E 5 55  ? 141.537 150.877 141.810 1.00 66.08  ? 55  SER S CB  1 
ATOM 7266 O OG  . SER E 5 55  ? 142.559 150.725 142.778 1.00 65.31  ? 55  SER S OG  1 
ATOM 7267 N N   . GLY E 5 56  ? 137.905 150.167 141.609 1.00 67.98  ? 56  GLY S N   1 
ATOM 7268 C CA  . GLY E 5 56  ? 136.811 150.234 140.663 1.00 69.76  ? 56  GLY S CA  1 
ATOM 7269 C C   . GLY E 5 56  ? 136.051 151.543 140.706 1.00 72.41  ? 56  GLY S C   1 
ATOM 7270 O O   . GLY E 5 56  ? 135.971 152.253 139.700 1.00 77.73  ? 56  GLY S O   1 
ATOM 7271 N N   . THR E 5 57  ? 135.489 151.874 141.864 1.00 61.43  ? 57  THR S N   1 
ATOM 7272 C CA  . THR E 5 57  ? 134.695 153.083 142.041 1.00 58.14  ? 57  THR S CA  1 
ATOM 7273 C C   . THR E 5 57  ? 135.439 154.046 142.955 1.00 60.13  ? 57  THR S C   1 
ATOM 7274 O O   . THR E 5 57  ? 135.872 153.664 144.046 1.00 63.87  ? 57  THR S O   1 
ATOM 7275 C CB  . THR E 5 57  ? 133.318 152.753 142.622 1.00 62.69  ? 57  THR S CB  1 
ATOM 7276 O OG1 . THR E 5 57  ? 132.446 152.323 141.570 1.00 70.56  ? 57  THR S OG1 1 
ATOM 7277 C CG2 . THR E 5 57  ? 132.714 153.973 143.300 1.00 59.84  ? 57  THR S CG2 1 
ATOM 7278 N N   . ILE E 5 58  ? 135.589 155.289 142.503 1.00 59.65  ? 58  ILE S N   1 
ATOM 7279 C CA  . ILE E 5 58  ? 136.284 156.330 143.249 1.00 55.49  ? 58  ILE S CA  1 
ATOM 7280 C C   . ILE E 5 58  ? 135.404 157.569 143.296 1.00 49.10  ? 58  ILE S C   1 
ATOM 7281 O O   . ILE E 5 58  ? 134.833 157.977 142.279 1.00 58.58  ? 58  ILE S O   1 
ATOM 7282 C CB  . ILE E 5 58  ? 137.656 156.661 142.624 1.00 53.12  ? 58  ILE S CB  1 
ATOM 7283 C CG1 . ILE E 5 58  ? 138.538 155.413 142.573 1.00 54.34  ? 58  ILE S CG1 1 
ATOM 7284 C CG2 . ILE E 5 58  ? 138.340 157.770 143.395 1.00 52.11  ? 58  ILE S CG2 1 
ATOM 7285 C CD1 . ILE E 5 58  ? 139.859 155.629 141.877 1.00 57.46  ? 58  ILE S CD1 1 
ATOM 7286 N N   . TYR E 5 59  ? 135.293 158.165 144.480 1.00 51.05  ? 59  TYR S N   1 
ATOM 7287 C CA  . TYR E 5 59  ? 134.515 159.377 144.680 1.00 54.03  ? 59  TYR S CA  1 
ATOM 7288 C C   . TYR E 5 59  ? 135.398 160.443 145.309 1.00 61.54  ? 59  TYR S C   1 
ATOM 7289 O O   . TYR E 5 59  ? 136.473 160.156 145.841 1.00 68.67  ? 59  TYR S O   1 
ATOM 7290 C CB  . TYR E 5 59  ? 133.291 159.119 145.567 1.00 58.80  ? 59  TYR S CB  1 
ATOM 7291 C CG  . TYR E 5 59  ? 132.205 158.311 144.896 1.00 56.74  ? 59  TYR S CG  1 
ATOM 7292 C CD1 . TYR E 5 59  ? 131.718 158.669 143.648 1.00 59.14  ? 59  TYR S CD1 1 
ATOM 7293 C CD2 . TYR E 5 59  ? 131.674 157.184 145.508 1.00 59.00  ? 59  TYR S CD2 1 
ATOM 7294 C CE1 . TYR E 5 59  ? 130.726 157.932 143.030 1.00 64.44  ? 59  TYR S CE1 1 
ATOM 7295 C CE2 . TYR E 5 59  ? 130.685 156.441 144.898 1.00 60.85  ? 59  TYR S CE2 1 
ATOM 7296 C CZ  . TYR E 5 59  ? 130.215 156.818 143.660 1.00 65.68  ? 59  TYR S CZ  1 
ATOM 7297 O OH  . TYR E 5 59  ? 129.228 156.079 143.049 1.00 64.91  ? 59  TYR S OH  1 
ATOM 7298 N N   . TYR E 5 60  ? 134.936 161.688 145.235 1.00 62.07  ? 60  TYR S N   1 
ATOM 7299 C CA  . TYR E 5 60  ? 135.646 162.811 145.827 1.00 65.10  ? 60  TYR S CA  1 
ATOM 7300 C C   . TYR E 5 60  ? 134.646 163.779 146.438 1.00 63.20  ? 60  TYR S C   1 
ATOM 7301 O O   . TYR E 5 60  ? 133.495 163.865 146.003 1.00 61.51  ? 60  TYR S O   1 
ATOM 7302 C CB  . TYR E 5 60  ? 136.511 163.551 144.800 1.00 61.55  ? 60  TYR S CB  1 
ATOM 7303 C CG  . TYR E 5 60  ? 137.749 162.801 144.373 1.00 56.37  ? 60  TYR S CG  1 
ATOM 7304 C CD1 . TYR E 5 60  ? 138.938 162.932 145.075 1.00 56.04  ? 60  TYR S CD1 1 
ATOM 7305 C CD2 . TYR E 5 60  ? 137.731 161.971 143.263 1.00 61.09  ? 60  TYR S CD2 1 
ATOM 7306 C CE1 . TYR E 5 60  ? 140.073 162.251 144.686 1.00 62.03  ? 60  TYR S CE1 1 
ATOM 7307 C CE2 . TYR E 5 60  ? 138.861 161.286 142.866 1.00 68.75  ? 60  TYR S CE2 1 
ATOM 7308 C CZ  . TYR E 5 60  ? 140.029 161.430 143.581 1.00 69.43  ? 60  TYR S CZ  1 
ATOM 7309 O OH  . TYR E 5 60  ? 141.157 160.748 143.188 1.00 69.63  ? 60  TYR S OH  1 
ATOM 7310 N N   . ALA E 5 61  ? 135.100 164.508 147.452 1.00 64.69  ? 61  ALA S N   1 
ATOM 7311 C CA  . ALA E 5 61  ? 134.284 165.560 148.035 1.00 66.64  ? 61  ALA S CA  1 
ATOM 7312 C C   . ALA E 5 61  ? 134.174 166.735 147.072 1.00 73.87  ? 61  ALA S C   1 
ATOM 7313 O O   . ALA E 5 61  ? 135.064 166.985 146.256 1.00 75.03  ? 61  ALA S O   1 
ATOM 7314 C CB  . ALA E 5 61  ? 134.875 166.022 149.366 1.00 66.07  ? 61  ALA S CB  1 
ATOM 7315 N N   . ASP E 5 62  ? 133.056 167.458 147.169 1.00 87.38  ? 62  ASP S N   1 
ATOM 7316 C CA  . ASP E 5 62  ? 132.838 168.600 146.287 1.00 86.47  ? 62  ASP S CA  1 
ATOM 7317 C C   . ASP E 5 62  ? 133.850 169.710 146.537 1.00 85.45  ? 62  ASP S C   1 
ATOM 7318 O O   . ASP E 5 62  ? 134.143 170.496 145.629 1.00 85.07  ? 62  ASP S O   1 
ATOM 7319 C CB  . ASP E 5 62  ? 131.415 169.129 146.458 1.00 87.03  ? 62  ASP S CB  1 
ATOM 7320 C CG  . ASP E 5 62  ? 130.414 168.026 146.740 1.00 85.67  ? 62  ASP S CG  1 
ATOM 7321 O OD1 . ASP E 5 62  ? 130.292 167.104 145.905 1.00 84.13  ? 62  ASP S OD1 1 
ATOM 7322 O OD2 . ASP E 5 62  ? 129.749 168.078 147.796 1.00 85.63  ? 62  ASP S OD2 1 
ATOM 7323 N N   . THR E 5 63  ? 134.388 169.795 147.756 1.00 90.08  ? 63  THR S N   1 
ATOM 7324 C CA  . THR E 5 63  ? 135.364 170.834 148.066 1.00 90.78  ? 63  THR S CA  1 
ATOM 7325 C C   . THR E 5 63  ? 136.668 170.621 147.306 1.00 90.96  ? 63  THR S C   1 
ATOM 7326 O O   . THR E 5 63  ? 137.291 171.587 146.851 1.00 94.05  ? 63  THR S O   1 
ATOM 7327 C CB  . THR E 5 63  ? 135.623 170.877 149.572 1.00 91.65  ? 63  THR S CB  1 
ATOM 7328 O OG1 . THR E 5 63  ? 134.378 171.005 150.269 1.00 94.21  ? 63  THR S OG1 1 
ATOM 7329 C CG2 . THR E 5 63  ? 136.518 172.055 149.928 1.00 87.90  ? 63  THR S CG2 1 
ATOM 7330 N N   . VAL E 5 64  ? 137.094 169.368 147.152 1.00 88.79  ? 64  VAL S N   1 
ATOM 7331 C CA  . VAL E 5 64  ? 138.389 169.072 146.549 1.00 89.18  ? 64  VAL S CA  1 
ATOM 7332 C C   . VAL E 5 64  ? 138.218 168.209 145.306 1.00 92.18  ? 64  VAL S C   1 
ATOM 7333 O O   . VAL E 5 64  ? 139.122 167.451 144.937 1.00 91.65  ? 64  VAL S O   1 
ATOM 7334 C CB  . VAL E 5 64  ? 139.322 168.389 147.565 1.00 86.00  ? 64  VAL S CB  1 
ATOM 7335 C CG1 . VAL E 5 64  ? 139.637 169.336 148.709 1.00 87.71  ? 64  VAL S CG1 1 
ATOM 7336 C CG2 . VAL E 5 64  ? 138.690 167.111 148.090 1.00 85.09  ? 64  VAL S CG2 1 
ATOM 7337 N N   . LYS E 5 65  ? 137.068 168.320 144.647 1.00 91.32  ? 65  LYS S N   1 
ATOM 7338 C CA  . LYS E 5 65  ? 136.834 167.552 143.430 1.00 88.68  ? 65  LYS S CA  1 
ATOM 7339 C C   . LYS E 5 65  ? 137.721 168.063 142.303 1.00 91.65  ? 65  LYS S C   1 
ATOM 7340 O O   . LYS E 5 65  ? 137.765 169.266 142.028 1.00 95.33  ? 65  LYS S O   1 
ATOM 7341 C CB  . LYS E 5 65  ? 135.364 167.630 143.023 1.00 87.61  ? 65  LYS S CB  1 
ATOM 7342 C CG  . LYS E 5 65  ? 135.025 166.804 141.792 1.00 91.46  ? 65  LYS S CG  1 
ATOM 7343 C CD  . LYS E 5 65  ? 133.543 166.482 141.728 1.00 92.13  ? 65  LYS S CD  1 
ATOM 7344 C CE  . LYS E 5 65  ? 133.206 165.290 142.606 1.00 93.44  ? 65  LYS S CE  1 
ATOM 7345 N NZ  . LYS E 5 65  ? 131.796 164.849 142.429 1.00 94.09  ? 65  LYS S NZ  1 
ATOM 7346 N N   . GLY E 5 66  ? 138.430 167.144 141.650 1.00 90.17  ? 66  GLY S N   1 
ATOM 7347 C CA  . GLY E 5 66  ? 139.327 167.494 140.570 1.00 91.11  ? 66  GLY S CA  1 
ATOM 7348 C C   . GLY E 5 66  ? 140.676 168.018 141.005 1.00 94.50  ? 66  GLY S C   1 
ATOM 7349 O O   . GLY E 5 66  ? 141.514 168.314 140.143 1.00 95.19  ? 66  GLY S O   1 
ATOM 7350 N N   . ARG E 5 67  ? 140.916 168.138 142.309 1.00 93.45  ? 67  ARG S N   1 
ATOM 7351 C CA  . ARG E 5 67  ? 142.174 168.643 142.841 1.00 92.08  ? 67  ARG S CA  1 
ATOM 7352 C C   . ARG E 5 67  ? 143.021 167.574 143.508 1.00 94.71  ? 67  ARG S C   1 
ATOM 7353 O O   . ARG E 5 67  ? 144.250 167.660 143.462 1.00 91.09  ? 67  ARG S O   1 
ATOM 7354 C CB  . ARG E 5 67  ? 141.904 169.766 143.850 1.00 89.99  ? 67  ARG S CB  1 
ATOM 7355 C CG  . ARG E 5 67  ? 142.848 170.947 143.751 1.00 91.73  ? 67  ARG S CG  1 
ATOM 7356 C CD  . ARG E 5 67  ? 142.369 172.078 144.640 1.00 93.00  ? 67  ARG S CD  1 
ATOM 7357 N NE  . ARG E 5 67  ? 142.507 171.756 146.054 1.00 91.04  ? 67  ARG S NE  1 
ATOM 7358 C CZ  . ARG E 5 67  ? 141.814 172.336 147.024 1.00 92.31  ? 67  ARG S CZ  1 
ATOM 7359 N NH1 . ARG E 5 67  ? 140.909 173.266 146.765 1.00 92.46  ? 67  ARG S NH1 1 
ATOM 7360 N NH2 . ARG E 5 67  ? 142.029 171.971 148.284 1.00 93.48  ? 67  ARG S NH2 1 
ATOM 7361 N N   . PHE E 5 68  ? 142.397 166.577 144.126 1.00 89.32  ? 68  PHE S N   1 
ATOM 7362 C CA  . PHE E 5 68  ? 143.098 165.483 144.778 1.00 85.41  ? 68  PHE S CA  1 
ATOM 7363 C C   . PHE E 5 68  ? 143.072 164.243 143.892 1.00 84.21  ? 68  PHE S C   1 
ATOM 7364 O O   . PHE E 5 68  ? 142.193 164.072 143.044 1.00 82.09  ? 68  PHE S O   1 
ATOM 7365 C CB  . PHE E 5 68  ? 142.466 165.161 146.137 1.00 85.64  ? 68  PHE S CB  1 
ATOM 7366 C CG  . PHE E 5 68  ? 142.736 166.190 147.201 1.00 81.93  ? 68  PHE S CG  1 
ATOM 7367 C CD1 . PHE E 5 68  ? 143.400 167.367 146.906 1.00 86.57  ? 68  PHE S CD1 1 
ATOM 7368 C CD2 . PHE E 5 68  ? 142.311 165.978 148.500 1.00 82.65  ? 68  PHE S CD2 1 
ATOM 7369 C CE1 . PHE E 5 68  ? 143.640 168.309 147.887 1.00 85.74  ? 68  PHE S CE1 1 
ATOM 7370 C CE2 . PHE E 5 68  ? 142.548 166.916 149.484 1.00 84.08  ? 68  PHE S CE2 1 
ATOM 7371 C CZ  . PHE E 5 68  ? 143.212 168.082 149.177 1.00 84.87  ? 68  PHE S CZ  1 
ATOM 7372 N N   . THR E 5 69  ? 144.055 163.372 144.101 1.00 85.52  ? 69  THR S N   1 
ATOM 7373 C CA  . THR E 5 69  ? 144.119 162.102 143.392 1.00 85.56  ? 69  THR S CA  1 
ATOM 7374 C C   . THR E 5 69  ? 144.432 160.997 144.387 1.00 87.10  ? 69  THR S C   1 
ATOM 7375 O O   . THR E 5 69  ? 145.384 161.110 145.164 1.00 86.77  ? 69  THR S O   1 
ATOM 7376 C CB  . THR E 5 69  ? 145.176 162.130 142.281 1.00 88.35  ? 69  THR S CB  1 
ATOM 7377 O OG1 . THR E 5 69  ? 145.037 163.336 141.520 1.00 91.47  ? 69  THR S OG1 1 
ATOM 7378 C CG2 . THR E 5 69  ? 145.005 160.934 141.359 1.00 85.34  ? 69  THR S CG2 1 
ATOM 7379 N N   . ILE E 5 70  ? 143.633 159.935 144.358 1.00 79.13  ? 70  ILE S N   1 
ATOM 7380 C CA  . ILE E 5 70  ? 143.786 158.801 145.258 1.00 77.54  ? 70  ILE S CA  1 
ATOM 7381 C C   . ILE E 5 70  ? 144.138 157.571 144.432 1.00 75.77  ? 70  ILE S C   1 
ATOM 7382 O O   . ILE E 5 70  ? 143.589 157.361 143.344 1.00 74.00  ? 70  ILE S O   1 
ATOM 7383 C CB  . ILE E 5 70  ? 142.514 158.574 146.107 1.00 75.46  ? 70  ILE S CB  1 
ATOM 7384 C CG1 . ILE E 5 70  ? 142.792 157.618 147.268 1.00 73.88  ? 70  ILE S CG1 1 
ATOM 7385 C CG2 . ILE E 5 70  ? 141.359 158.076 145.261 1.00 71.79  ? 70  ILE S CG2 1 
ATOM 7386 C CD1 . ILE E 5 70  ? 141.636 157.496 148.233 1.00 67.48  ? 70  ILE S CD1 1 
ATOM 7387 N N   . SER E 5 71  ? 145.086 156.782 144.930 1.00 71.93  ? 71  SER S N   1 
ATOM 7388 C CA  . SER E 5 71  ? 145.564 155.607 144.220 1.00 71.74  ? 71  SER S CA  1 
ATOM 7389 C C   . SER E 5 71  ? 145.743 154.460 145.201 1.00 72.95  ? 71  SER S C   1 
ATOM 7390 O O   . SER E 5 71  ? 145.968 154.669 146.395 1.00 70.81  ? 71  SER S O   1 
ATOM 7391 C CB  . SER E 5 71  ? 146.882 155.885 143.486 1.00 76.49  ? 71  SER S CB  1 
ATOM 7392 O OG  . SER E 5 71  ? 147.914 156.221 144.396 1.00 73.24  ? 71  SER S OG  1 
ATOM 7393 N N   . ARG E 5 72  ? 145.645 153.242 144.677 1.00 76.57  ? 72  ARG S N   1 
ATOM 7394 C CA  . ARG E 5 72  ? 145.689 152.029 145.478 1.00 73.97  ? 72  ARG S CA  1 
ATOM 7395 C C   . ARG E 5 72  ? 146.759 151.104 144.921 1.00 76.76  ? 72  ARG S C   1 
ATOM 7396 O O   . ARG E 5 72  ? 146.823 150.889 143.707 1.00 77.75  ? 72  ARG S O   1 
ATOM 7397 C CB  . ARG E 5 72  ? 144.330 151.328 145.466 1.00 76.28  ? 72  ARG S CB  1 
ATOM 7398 C CG  . ARG E 5 72  ? 144.148 150.270 146.525 1.00 74.99  ? 72  ARG S CG  1 
ATOM 7399 C CD  . ARG E 5 72  ? 142.728 150.319 147.059 1.00 71.43  ? 72  ARG S CD  1 
ATOM 7400 N NE  . ARG E 5 72  ? 142.561 149.499 148.250 1.00 69.01  ? 72  ARG S NE  1 
ATOM 7401 C CZ  . ARG E 5 72  ? 141.731 148.470 148.335 1.00 72.70  ? 72  ARG S CZ  1 
ATOM 7402 N NH1 . ARG E 5 72  ? 140.986 148.097 147.309 1.00 71.62  ? 72  ARG S NH1 1 
ATOM 7403 N NH2 . ARG E 5 72  ? 141.656 147.790 149.474 1.00 75.88  ? 72  ARG S NH2 1 
ATOM 7404 N N   . ASP E 5 73  ? 147.592 150.560 145.804 1.00 84.92  ? 73  ASP S N   1 
ATOM 7405 C CA  . ASP E 5 73  ? 148.674 149.650 145.431 1.00 84.79  ? 73  ASP S CA  1 
ATOM 7406 C C   . ASP E 5 73  ? 148.426 148.342 146.174 1.00 87.82  ? 73  ASP S C   1 
ATOM 7407 O O   . ASP E 5 73  ? 148.939 148.138 147.278 1.00 88.26  ? 73  ASP S O   1 
ATOM 7408 C CB  . ASP E 5 73  ? 150.040 150.240 145.770 1.00 86.03  ? 73  ASP S CB  1 
ATOM 7409 C CG  . ASP E 5 73  ? 151.150 149.674 144.907 1.00 87.38  ? 73  ASP S CG  1 
ATOM 7410 O OD1 . ASP E 5 73  ? 150.841 149.026 143.888 1.00 90.57  ? 73  ASP S OD1 1 
ATOM 7411 O OD2 . ASP E 5 73  ? 152.334 149.859 145.262 1.00 85.03  ? 73  ASP S OD2 1 
ATOM 7412 N N   . ASP E 5 74  ? 147.633 147.460 145.566 1.00 89.66  ? 74  ASP S N   1 
ATOM 7413 C CA  . ASP E 5 74  ? 147.211 146.248 146.266 1.00 90.37  ? 74  ASP S CA  1 
ATOM 7414 C C   . ASP E 5 74  ? 148.372 145.328 146.618 1.00 93.58  ? 74  ASP S C   1 
ATOM 7415 O O   . ASP E 5 74  ? 148.439 144.876 147.773 1.00 90.70  ? 74  ASP S O   1 
ATOM 7416 C CB  . ASP E 5 74  ? 146.150 145.515 145.438 1.00 88.52  ? 74  ASP S CB  1 
ATOM 7417 C CG  . ASP E 5 74  ? 144.804 146.209 145.455 1.00 87.72  ? 74  ASP S CG  1 
ATOM 7418 O OD1 . ASP E 5 74  ? 144.503 146.922 146.437 1.00 85.00  ? 74  ASP S OD1 1 
ATOM 7419 O OD2 . ASP E 5 74  ? 144.038 146.024 144.490 1.00 88.65  ? 74  ASP S OD2 1 
ATOM 7420 N N   . PRO E 5 75  ? 149.374 145.069 145.756 1.00 104.09 ? 75  PRO S N   1 
ATOM 7421 C CA  . PRO E 5 75  ? 150.415 144.132 146.141 1.00 99.64  ? 75  PRO S CA  1 
ATOM 7422 C C   . PRO E 5 75  ? 151.227 144.700 147.302 1.00 94.33  ? 75  PRO S C   1 
ATOM 7423 O O   . PRO E 5 75  ? 151.541 143.960 148.194 1.00 95.32  ? 75  PRO S O   1 
ATOM 7424 C CB  . PRO E 5 75  ? 151.273 144.054 144.883 1.00 99.53  ? 75  PRO S CB  1 
ATOM 7425 C CG  . PRO E 5 75  ? 151.045 145.364 144.183 1.00 101.64 ? 75  PRO S CG  1 
ATOM 7426 C CD  . PRO E 5 75  ? 149.574 145.616 144.408 1.00 101.02 ? 75  PRO S CD  1 
ATOM 7427 N N   . LYS E 5 76  ? 151.513 145.993 147.270 1.00 86.15  ? 76  LYS S N   1 
ATOM 7428 C CA  . LYS E 5 76  ? 152.360 146.610 148.278 1.00 92.27  ? 76  LYS S CA  1 
ATOM 7429 C C   . LYS E 5 76  ? 151.625 146.908 149.577 1.00 95.87  ? 76  LYS S C   1 
ATOM 7430 O O   . LYS E 5 76  ? 152.281 147.241 150.571 1.00 94.63  ? 76  LYS S O   1 
ATOM 7431 C CB  . LYS E 5 76  ? 152.972 147.900 147.717 1.00 92.93  ? 76  LYS S CB  1 
ATOM 7432 C CG  . LYS E 5 76  ? 154.291 148.317 148.347 1.00 93.54  ? 76  LYS S CG  1 
ATOM 7433 C CD  . LYS E 5 76  ? 155.358 147.253 148.141 1.00 93.71  ? 76  LYS S CD  1 
ATOM 7434 C CE  . LYS E 5 76  ? 156.694 147.669 148.729 1.00 93.64  ? 76  LYS S CE  1 
ATOM 7435 N NZ  . LYS E 5 76  ? 156.591 148.047 150.162 1.00 95.92  ? 76  LYS S NZ  1 
ATOM 7436 N N   . ASN E 5 77  ? 150.298 146.785 149.601 1.00 86.32  ? 77  ASN S N   1 
ATOM 7437 C CA  . ASN E 5 77  ? 149.479 147.135 150.764 1.00 81.11  ? 77  ASN S CA  1 
ATOM 7438 C C   . ASN E 5 77  ? 149.739 148.576 151.203 1.00 82.21  ? 77  ASN S C   1 
ATOM 7439 O O   . ASN E 5 77  ? 150.103 148.857 152.347 1.00 84.80  ? 77  ASN S O   1 
ATOM 7440 C CB  . ASN E 5 77  ? 149.713 146.159 151.921 1.00 81.69  ? 77  ASN S CB  1 
ATOM 7441 C CG  . ASN E 5 77  ? 149.245 144.757 151.605 1.00 86.17  ? 77  ASN S CG  1 
ATOM 7442 O OD1 . ASN E 5 77  ? 149.156 144.364 150.445 1.00 86.77  ? 77  ASN S OD1 1 
ATOM 7443 N ND2 . ASN E 5 77  ? 148.932 143.993 152.646 1.00 83.58  ? 77  ASN S ND2 1 
ATOM 7444 N N   . THR E 5 78  ? 149.549 149.495 150.259 1.00 74.14  ? 78  THR S N   1 
ATOM 7445 C CA  . THR E 5 78  ? 149.761 150.914 150.503 1.00 73.23  ? 78  THR S CA  1 
ATOM 7446 C C   . THR E 5 78  ? 148.679 151.718 149.798 1.00 75.26  ? 78  THR S C   1 
ATOM 7447 O O   . THR E 5 78  ? 148.305 151.411 148.663 1.00 73.95  ? 78  THR S O   1 
ATOM 7448 C CB  . THR E 5 78  ? 151.149 151.363 150.021 1.00 75.37  ? 78  THR S CB  1 
ATOM 7449 O OG1 . THR E 5 78  ? 152.136 150.422 150.460 1.00 77.93  ? 78  THR S OG1 1 
ATOM 7450 C CG2 . THR E 5 78  ? 151.493 152.734 150.584 1.00 74.30  ? 78  THR S CG2 1 
ATOM 7451 N N   . LEU E 5 79  ? 148.179 152.747 150.479 1.00 78.11  ? 79  LEU S N   1 
ATOM 7452 C CA  . LEU E 5 79  ? 147.161 153.642 149.945 1.00 78.51  ? 79  LEU S CA  1 
ATOM 7453 C C   . LEU E 5 79  ? 147.723 155.056 149.897 1.00 77.93  ? 79  LEU S C   1 
ATOM 7454 O O   . LEU E 5 79  ? 148.285 155.537 150.886 1.00 77.09  ? 79  LEU S O   1 
ATOM 7455 C CB  . LEU E 5 79  ? 145.889 153.595 150.796 1.00 73.98  ? 79  LEU S CB  1 
ATOM 7456 C CG  . LEU E 5 79  ? 144.743 154.536 150.423 1.00 68.25  ? 79  LEU S CG  1 
ATOM 7457 C CD1 . LEU E 5 79  ? 143.835 153.886 149.398 1.00 72.85  ? 79  LEU S CD1 1 
ATOM 7458 C CD2 . LEU E 5 79  ? 143.956 154.918 151.660 1.00 67.02  ? 79  LEU S CD2 1 
ATOM 7459 N N   . PHE E 5 80  ? 147.574 155.716 148.752 1.00 75.11  ? 80  PHE S N   1 
ATOM 7460 C CA  . PHE E 5 80  ? 148.166 157.024 148.519 1.00 73.04  ? 80  PHE S CA  1 
ATOM 7461 C C   . PHE E 5 80  ? 147.090 158.091 148.366 1.00 75.23  ? 80  PHE S C   1 
ATOM 7462 O O   . PHE E 5 80  ? 145.895 157.804 148.271 1.00 77.19  ? 80  PHE S O   1 
ATOM 7463 C CB  . PHE E 5 80  ? 149.060 157.008 147.274 1.00 80.21  ? 80  PHE S CB  1 
ATOM 7464 C CG  . PHE E 5 80  ? 150.068 155.897 147.259 1.00 77.87  ? 80  PHE S CG  1 
ATOM 7465 C CD1 . PHE E 5 80  ? 151.248 156.008 147.972 1.00 74.10  ? 80  PHE S CD1 1 
ATOM 7466 C CD2 . PHE E 5 80  ? 149.842 154.749 146.519 1.00 75.24  ? 80  PHE S CD2 1 
ATOM 7467 C CE1 . PHE E 5 80  ? 152.181 154.993 147.956 1.00 73.14  ? 80  PHE S CE1 1 
ATOM 7468 C CE2 . PHE E 5 80  ? 150.772 153.729 146.499 1.00 76.23  ? 80  PHE S CE2 1 
ATOM 7469 C CZ  . PHE E 5 80  ? 151.943 153.852 147.219 1.00 77.23  ? 80  PHE S CZ  1 
ATOM 7470 N N   . LEU E 5 81  ? 147.544 159.344 148.343 1.00 81.94  ? 81  LEU S N   1 
ATOM 7471 C CA  . LEU E 5 81  ? 146.665 160.487 148.105 1.00 79.25  ? 81  LEU S CA  1 
ATOM 7472 C C   . LEU E 5 81  ? 147.522 161.620 147.558 1.00 83.17  ? 81  LEU S C   1 
ATOM 7473 O O   . LEU E 5 81  ? 148.341 162.181 148.292 1.00 80.12  ? 81  LEU S O   1 
ATOM 7474 C CB  . LEU E 5 81  ? 145.950 160.907 149.382 1.00 80.60  ? 81  LEU S CB  1 
ATOM 7475 C CG  . LEU E 5 81  ? 145.152 162.208 149.282 1.00 78.65  ? 81  LEU S CG  1 
ATOM 7476 C CD1 . LEU E 5 81  ? 143.800 161.956 148.636 1.00 80.75  ? 81  LEU S CD1 1 
ATOM 7477 C CD2 . LEU E 5 81  ? 144.988 162.857 150.646 1.00 75.85  ? 81  LEU S CD2 1 
ATOM 7478 N N   . GLN E 5 82  ? 147.336 161.954 146.285 1.00 92.08  ? 82  GLN S N   1 
ATOM 7479 C CA  . GLN E 5 82  ? 148.115 162.995 145.628 1.00 90.58  ? 82  GLN S CA  1 
ATOM 7480 C C   . GLN E 5 82  ? 147.277 164.260 145.496 1.00 89.77  ? 82  GLN S C   1 
ATOM 7481 O O   . GLN E 5 82  ? 146.171 164.224 144.947 1.00 87.96  ? 82  GLN S O   1 
ATOM 7482 C CB  . GLN E 5 82  ? 148.595 162.532 144.252 1.00 89.54  ? 82  GLN S CB  1 
ATOM 7483 C CG  . GLN E 5 82  ? 149.273 163.621 143.438 1.00 91.82  ? 82  GLN S CG  1 
ATOM 7484 C CD  . GLN E 5 82  ? 150.663 163.948 143.950 1.00 95.07  ? 82  GLN S CD  1 
ATOM 7485 O OE1 . GLN E 5 82  ? 151.002 165.112 144.161 1.00 94.00  ? 82  GLN S OE1 1 
ATOM 7486 N NE2 . GLN E 5 82  ? 151.475 162.917 144.155 1.00 94.02  ? 82  GLN S NE2 1 
ATOM 7487 N N   . MET E 5 83  ? 147.808 165.372 145.998 1.00 98.19  ? 83  MET S N   1 
ATOM 7488 C CA  . MET E 5 83  ? 147.132 166.661 145.971 1.00 101.68 ? 83  MET S CA  1 
ATOM 7489 C C   . MET E 5 83  ? 147.934 167.630 145.115 1.00 103.86 ? 83  MET S C   1 
ATOM 7490 O O   . MET E 5 83  ? 149.147 167.772 145.302 1.00 101.67 ? 83  MET S O   1 
ATOM 7491 C CB  . MET E 5 83  ? 146.957 167.210 147.387 1.00 103.76 ? 83  MET S CB  1 
ATOM 7492 C CG  . MET E 5 83  ? 146.588 166.146 148.407 1.00 104.17 ? 83  MET S CG  1 
ATOM 7493 S SD  . MET E 5 83  ? 146.318 166.813 150.056 1.00 101.79 ? 83  MET S SD  1 
ATOM 7494 C CE  . MET E 5 83  ? 148.004 166.903 150.636 1.00 98.16  ? 83  MET S CE  1 
ATOM 7495 N N   . THR E 5 84  ? 147.255 168.297 144.179 1.00 110.98 ? 84  THR S N   1 
ATOM 7496 C CA  . THR E 5 84  ? 147.948 169.154 143.222 1.00 110.47 ? 84  THR S CA  1 
ATOM 7497 C C   . THR E 5 84  ? 148.242 170.531 143.811 1.00 110.28 ? 84  THR S C   1 
ATOM 7498 O O   . THR E 5 84  ? 149.403 170.942 143.906 1.00 109.23 ? 84  THR S O   1 
ATOM 7499 C CB  . THR E 5 84  ? 147.122 169.281 141.938 1.00 110.54 ? 84  THR S CB  1 
ATOM 7500 O OG1 . THR E 5 84  ? 147.227 168.069 141.182 1.00 112.07 ? 84  THR S OG1 1 
ATOM 7501 C CG2 . THR E 5 84  ? 147.628 170.438 141.088 1.00 111.03 ? 84  THR S CG2 1 
ATOM 7502 N N   . SER E 5 85  ? 147.201 171.260 144.208 1.00 107.31 ? 85  SER S N   1 
ATOM 7503 C CA  . SER E 5 85  ? 147.341 172.604 144.755 1.00 106.78 ? 85  SER S CA  1 
ATOM 7504 C C   . SER E 5 85  ? 146.706 172.652 146.136 1.00 109.17 ? 85  SER S C   1 
ATOM 7505 O O   . SER E 5 85  ? 145.581 172.178 146.322 1.00 110.23 ? 85  SER S O   1 
ATOM 7506 C CB  . SER E 5 85  ? 146.695 173.644 143.837 1.00 104.79 ? 85  SER S CB  1 
ATOM 7507 O OG  . SER E 5 85  ? 145.288 173.486 143.800 1.00 104.67 ? 85  SER S OG  1 
ATOM 7508 N N   . LEU E 5 86  ? 147.425 173.226 147.096 1.00 105.70 ? 86  LEU S N   1 
ATOM 7509 C CA  . LEU E 5 86  ? 146.988 173.287 148.484 1.00 103.59 ? 86  LEU S CA  1 
ATOM 7510 C C   . LEU E 5 86  ? 146.726 174.732 148.881 1.00 101.59 ? 86  LEU S C   1 
ATOM 7511 O O   . LEU E 5 86  ? 147.602 175.591 148.730 1.00 103.69 ? 86  LEU S O   1 
ATOM 7512 C CB  . LEU E 5 86  ? 148.034 172.669 149.414 1.00 102.91 ? 86  LEU S CB  1 
ATOM 7513 C CG  . LEU E 5 86  ? 147.966 171.154 149.616 1.00 104.37 ? 86  LEU S CG  1 
ATOM 7514 C CD1 . LEU E 5 86  ? 148.535 170.417 148.415 1.00 102.80 ? 86  LEU S CD1 1 
ATOM 7515 C CD2 . LEU E 5 86  ? 148.696 170.754 150.887 1.00 105.81 ? 86  LEU S CD2 1 
ATOM 7516 N N   . ARG E 5 87  ? 145.526 174.996 149.387 1.00 96.49  ? 87  ARG S N   1 
ATOM 7517 C CA  . ARG E 5 87  ? 145.179 176.306 149.912 1.00 97.69  ? 87  ARG S CA  1 
ATOM 7518 C C   . ARG E 5 87  ? 145.478 176.342 151.410 1.00 98.93  ? 87  ARG S C   1 
ATOM 7519 O O   . ARG E 5 87  ? 146.080 175.421 151.968 1.00 99.83  ? 87  ARG S O   1 
ATOM 7520 C CB  . ARG E 5 87  ? 143.713 176.625 149.629 1.00 96.80  ? 87  ARG S CB  1 
ATOM 7521 C CG  . ARG E 5 87  ? 143.196 176.096 148.306 1.00 96.52  ? 87  ARG S CG  1 
ATOM 7522 C CD  . ARG E 5 87  ? 141.680 176.036 148.311 1.00 95.00  ? 87  ARG S CD  1 
ATOM 7523 N NE  . ARG E 5 87  ? 141.080 177.267 147.813 1.00 98.02  ? 87  ARG S NE  1 
ATOM 7524 C CZ  . ARG E 5 87  ? 140.772 177.488 146.543 1.00 99.64  ? 87  ARG S CZ  1 
ATOM 7525 N NH1 . ARG E 5 87  ? 140.995 176.577 145.609 1.00 98.36  ? 87  ARG S NH1 1 
ATOM 7526 N NH2 . ARG E 5 87  ? 140.225 178.650 146.200 1.00 99.29  ? 87  ARG S NH2 1 
ATOM 7527 N N   . SER E 5 88  ? 145.053 177.411 152.081 1.00 99.08  ? 88  SER S N   1 
ATOM 7528 C CA  . SER E 5 88  ? 145.172 177.485 153.530 1.00 97.95  ? 88  SER S CA  1 
ATOM 7529 C C   . SER E 5 88  ? 144.057 176.739 154.249 1.00 96.27  ? 88  SER S C   1 
ATOM 7530 O O   . SER E 5 88  ? 144.119 176.599 155.474 1.00 96.12  ? 88  SER S O   1 
ATOM 7531 C CB  . SER E 5 88  ? 145.188 178.946 153.985 1.00 97.42  ? 88  SER S CB  1 
ATOM 7532 O OG  . SER E 5 88  ? 146.342 179.616 153.508 1.00 99.28  ? 88  SER S OG  1 
ATOM 7533 N N   . GLU E 5 89  ? 143.046 176.266 153.524 1.00 84.85  ? 89  GLU S N   1 
ATOM 7534 C CA  . GLU E 5 89  ? 141.939 175.525 154.111 1.00 85.70  ? 89  GLU S CA  1 
ATOM 7535 C C   . GLU E 5 89  ? 142.168 174.020 154.119 1.00 83.84  ? 89  GLU S C   1 
ATOM 7536 O O   . GLU E 5 89  ? 141.319 173.283 154.631 1.00 86.25  ? 89  GLU S O   1 
ATOM 7537 C CB  . GLU E 5 89  ? 140.640 175.842 153.364 1.00 83.58  ? 89  GLU S CB  1 
ATOM 7538 N N   . ASP E 5 90  ? 143.281 173.546 153.565 1.00 79.40  ? 90  ASP S N   1 
ATOM 7539 C CA  . ASP E 5 90  ? 143.576 172.120 153.531 1.00 81.05  ? 90  ASP S CA  1 
ATOM 7540 C C   . ASP E 5 90  ? 144.356 171.638 154.746 1.00 82.87  ? 90  ASP S C   1 
ATOM 7541 O O   . ASP E 5 90  ? 144.592 170.431 154.867 1.00 82.45  ? 90  ASP S O   1 
ATOM 7542 C CB  . ASP E 5 90  ? 144.352 171.770 152.258 1.00 81.62  ? 90  ASP S CB  1 
ATOM 7543 C CG  . ASP E 5 90  ? 143.490 171.838 151.015 1.00 82.29  ? 90  ASP S CG  1 
ATOM 7544 O OD1 . ASP E 5 90  ? 142.338 172.308 151.117 1.00 84.97  ? 90  ASP S OD1 1 
ATOM 7545 O OD2 . ASP E 5 90  ? 143.961 171.423 149.936 1.00 82.40  ? 90  ASP S OD2 1 
ATOM 7546 N N   . THR E 5 91  ? 144.761 172.536 155.641 1.00 79.32  ? 91  THR S N   1 
ATOM 7547 C CA  . THR E 5 91  ? 145.494 172.127 156.832 1.00 79.34  ? 91  THR S CA  1 
ATOM 7548 C C   . THR E 5 91  ? 144.562 171.390 157.789 1.00 74.46  ? 91  THR S C   1 
ATOM 7549 O O   . THR E 5 91  ? 143.556 171.945 158.243 1.00 75.24  ? 91  THR S O   1 
ATOM 7550 C CB  . THR E 5 91  ? 146.132 173.340 157.511 1.00 77.48  ? 91  THR S CB  1 
ATOM 7551 O OG1 . THR E 5 91  ? 146.653 172.960 158.791 1.00 78.53  ? 91  THR S OG1 1 
ATOM 7552 C CG2 . THR E 5 91  ? 145.132 174.479 157.676 1.00 75.84  ? 91  THR S CG2 1 
ATOM 7553 N N   . ALA E 5 92  ? 144.897 170.139 158.091 1.00 66.24  ? 92  ALA S N   1 
ATOM 7554 C CA  . ALA E 5 92  ? 144.058 169.292 158.928 1.00 68.57  ? 92  ALA S CA  1 
ATOM 7555 C C   . ALA E 5 92  ? 144.824 168.019 159.251 1.00 71.10  ? 92  ALA S C   1 
ATOM 7556 O O   . ALA E 5 92  ? 145.898 167.759 158.703 1.00 75.90  ? 92  ALA S O   1 
ATOM 7557 C CB  . ALA E 5 92  ? 142.730 168.960 158.243 1.00 70.70  ? 92  ALA S CB  1 
ATOM 7558 N N   . MET E 5 93  ? 144.252 167.225 160.152 1.00 67.27  ? 93  MET S N   1 
ATOM 7559 C CA  . MET E 5 93  ? 144.792 165.923 160.521 1.00 61.41  ? 93  MET S CA  1 
ATOM 7560 C C   . MET E 5 93  ? 144.075 164.873 159.680 1.00 63.56  ? 93  MET S C   1 
ATOM 7561 O O   . MET E 5 93  ? 142.862 164.687 159.813 1.00 72.31  ? 93  MET S O   1 
ATOM 7562 C CB  . MET E 5 93  ? 144.604 165.666 162.015 1.00 63.55  ? 93  MET S CB  1 
ATOM 7563 C CG  . MET E 5 93  ? 145.249 164.393 162.534 1.00 66.01  ? 93  MET S CG  1 
ATOM 7564 S SD  . MET E 5 93  ? 146.168 164.701 164.056 1.00 83.68  ? 93  MET S SD  1 
ATOM 7565 C CE  . MET E 5 93  ? 147.173 163.225 164.170 1.00 68.09  ? 93  MET S CE  1 
ATOM 7566 N N   . TYR E 5 94  ? 144.820 164.194 158.813 1.00 59.39  ? 94  TYR S N   1 
ATOM 7567 C CA  . TYR E 5 94  ? 144.236 163.261 157.858 1.00 60.91  ? 94  TYR S CA  1 
ATOM 7568 C C   . TYR E 5 94  ? 144.217 161.852 158.436 1.00 65.86  ? 94  TYR S C   1 
ATOM 7569 O O   . TYR E 5 94  ? 145.238 161.360 158.925 1.00 69.48  ? 94  TYR S O   1 
ATOM 7570 C CB  . TYR E 5 94  ? 145.012 163.286 156.541 1.00 56.33  ? 94  TYR S CB  1 
ATOM 7571 C CG  . TYR E 5 94  ? 144.678 164.473 155.668 1.00 54.83  ? 94  TYR S CG  1 
ATOM 7572 C CD1 . TYR E 5 94  ? 145.099 165.750 156.009 1.00 57.99  ? 94  TYR S CD1 1 
ATOM 7573 C CD2 . TYR E 5 94  ? 143.943 164.316 154.502 1.00 59.83  ? 94  TYR S CD2 1 
ATOM 7574 C CE1 . TYR E 5 94  ? 144.795 166.837 155.218 1.00 59.03  ? 94  TYR S CE1 1 
ATOM 7575 C CE2 . TYR E 5 94  ? 143.636 165.398 153.703 1.00 63.03  ? 94  TYR S CE2 1 
ATOM 7576 C CZ  . TYR E 5 94  ? 144.065 166.656 154.066 1.00 60.03  ? 94  TYR S CZ  1 
ATOM 7577 O OH  . TYR E 5 94  ? 143.762 167.739 153.275 1.00 59.38  ? 94  TYR S OH  1 
ATOM 7578 N N   . TYR E 5 95  ? 143.054 161.210 158.373 1.00 56.02  ? 95  TYR S N   1 
ATOM 7579 C CA  . TYR E 5 95  ? 142.857 159.867 158.895 1.00 51.09  ? 95  TYR S CA  1 
ATOM 7580 C C   . TYR E 5 95  ? 142.652 158.885 157.749 1.00 52.34  ? 95  TYR S C   1 
ATOM 7581 O O   . TYR E 5 95  ? 142.145 159.246 156.684 1.00 64.79  ? 95  TYR S O   1 
ATOM 7582 C CB  . TYR E 5 95  ? 141.651 159.814 159.836 1.00 50.88  ? 95  TYR S CB  1 
ATOM 7583 C CG  . TYR E 5 95  ? 141.824 160.617 161.101 1.00 52.00  ? 95  TYR S CG  1 
ATOM 7584 C CD1 . TYR E 5 95  ? 142.502 160.095 162.191 1.00 55.06  ? 95  TYR S CD1 1 
ATOM 7585 C CD2 . TYR E 5 95  ? 141.304 161.898 161.207 1.00 54.37  ? 95  TYR S CD2 1 
ATOM 7586 C CE1 . TYR E 5 95  ? 142.661 160.826 163.350 1.00 60.94  ? 95  TYR S CE1 1 
ATOM 7587 C CE2 . TYR E 5 95  ? 141.457 162.637 162.360 1.00 52.61  ? 95  TYR S CE2 1 
ATOM 7588 C CZ  . TYR E 5 95  ? 142.137 162.097 163.428 1.00 56.47  ? 95  TYR S CZ  1 
ATOM 7589 O OH  . TYR E 5 95  ? 142.292 162.831 164.581 1.00 59.56  ? 95  TYR S OH  1 
ATOM 7590 N N   . CYS E 5 96  ? 143.051 157.637 157.980 1.00 49.47  ? 96  CYS S N   1 
ATOM 7591 C CA  . CYS E 5 96  ? 142.889 156.558 157.013 1.00 52.05  ? 96  CYS S CA  1 
ATOM 7592 C C   . CYS E 5 96  ? 141.942 155.531 157.617 1.00 55.94  ? 96  CYS S C   1 
ATOM 7593 O O   . CYS E 5 96  ? 142.201 155.014 158.708 1.00 70.68  ? 96  CYS S O   1 
ATOM 7594 C CB  . CYS E 5 96  ? 144.242 155.931 156.667 1.00 61.97  ? 96  CYS S CB  1 
ATOM 7595 S SG  . CYS E 5 96  ? 144.247 154.749 155.299 1.00 65.56  ? 96  CYS S SG  1 
ATOM 7596 N N   . VAL E 5 97  ? 140.847 155.244 156.916 1.00 21.43  ? 97  VAL S N   1 
ATOM 7597 C CA  . VAL E 5 97  ? 139.772 154.408 157.436 1.00 17.22  ? 97  VAL S CA  1 
ATOM 7598 C C   . VAL E 5 97  ? 139.482 153.289 156.449 1.00 23.29  ? 97  VAL S C   1 
ATOM 7599 O O   . VAL E 5 97  ? 139.383 153.527 155.241 1.00 45.18  ? 97  VAL S O   1 
ATOM 7600 C CB  . VAL E 5 97  ? 138.494 155.230 157.696 1.00 19.34  ? 97  VAL S CB  1 
ATOM 7601 C CG1 . VAL E 5 97  ? 137.481 154.399 158.451 1.00 35.61  ? 97  VAL S CG1 1 
ATOM 7602 C CG2 . VAL E 5 97  ? 138.820 156.504 158.455 1.00 25.92  ? 97  VAL S CG2 1 
ATOM 7603 N N   . ARG E 5 98  ? 139.338 152.069 156.961 1.00 34.79  ? 98  ARG S N   1 
ATOM 7604 C CA  . ARG E 5 98  ? 138.975 150.922 156.142 1.00 42.11  ? 98  ARG S CA  1 
ATOM 7605 C C   . ARG E 5 98  ? 137.467 150.708 156.175 1.00 45.03  ? 98  ARG S C   1 
ATOM 7606 O O   . ARG E 5 98  ? 136.788 151.081 157.133 1.00 55.41  ? 98  ARG S O   1 
ATOM 7607 C CB  . ARG E 5 98  ? 139.699 149.654 156.604 1.00 42.88  ? 98  ARG S CB  1 
ATOM 7608 C CG  . ARG E 5 98  ? 139.270 149.094 157.952 1.00 41.02  ? 98  ARG S CG  1 
ATOM 7609 C CD  . ARG E 5 98  ? 140.066 147.829 158.267 1.00 56.70  ? 98  ARG S CD  1 
ATOM 7610 N NE  . ARG E 5 98  ? 139.965 147.418 159.663 1.00 52.29  ? 98  ARG S NE  1 
ATOM 7611 C CZ  . ARG E 5 98  ? 139.252 146.391 160.105 1.00 47.29  ? 98  ARG S CZ  1 
ATOM 7612 N NH1 . ARG E 5 98  ? 138.571 145.615 159.281 1.00 45.72  ? 98  ARG S NH1 1 
ATOM 7613 N NH2 . ARG E 5 98  ? 139.229 146.131 161.408 1.00 48.50  ? 98  ARG S NH2 1 
ATOM 7614 N N   . SER E 5 99  ? 136.948 150.108 155.107 1.00 39.98  ? 99  SER S N   1 
ATOM 7615 C CA  . SER E 5 99  ? 135.506 149.933 154.955 1.00 30.30  ? 99  SER S CA  1 
ATOM 7616 C C   . SER E 5 99  ? 135.255 148.734 154.059 1.00 38.67  ? 99  SER S C   1 
ATOM 7617 O O   . SER E 5 99  ? 135.643 148.751 152.888 1.00 58.81  ? 99  SER S O   1 
ATOM 7618 C CB  . SER E 5 99  ? 134.871 151.181 154.355 1.00 28.09  ? 99  SER S CB  1 
ATOM 7619 O OG  . SER E 5 99  ? 135.466 151.502 153.114 1.00 53.10  ? 99  SER S OG  1 
ATOM 7620 N N   . ILE E 5 100 ? 134.603 147.707 154.593 1.00 17.22  ? 100 ILE S N   1 
ATOM 7621 C CA  . ILE E 5 100 ? 134.213 146.534 153.821 1.00 32.49  ? 100 ILE S CA  1 
ATOM 7622 C C   . ILE E 5 100 ? 132.693 146.482 153.781 1.00 41.70  ? 100 ILE S C   1 
ATOM 7623 O O   . ILE E 5 100 ? 132.032 146.600 154.820 1.00 51.48  ? 100 ILE S O   1 
ATOM 7624 C CB  . ILE E 5 100 ? 134.812 145.242 154.404 1.00 41.94  ? 100 ILE S CB  1 
ATOM 7625 C CG1 . ILE E 5 100 ? 134.393 144.034 153.565 1.00 39.26  ? 100 ILE S CG1 1 
ATOM 7626 C CG2 . ILE E 5 100 ? 134.432 145.066 155.870 1.00 43.55  ? 100 ILE S CG2 1 
ATOM 7627 C CD1 . ILE E 5 100 ? 135.303 142.841 153.718 1.00 39.83  ? 100 ILE S CD1 1 
ATOM 7628 N N   . TYR E 5 101 ? 132.138 146.337 152.582 1.00 41.92  ? 101 TYR S N   1 
ATOM 7629 C CA  . TYR E 5 101 ? 130.696 146.384 152.378 1.00 35.76  ? 101 TYR S CA  1 
ATOM 7630 C C   . TYR E 5 101 ? 130.188 145.029 151.908 1.00 36.88  ? 101 TYR S C   1 
ATOM 7631 O O   . TYR E 5 101 ? 130.623 144.523 150.868 1.00 43.06  ? 101 TYR S O   1 
ATOM 7632 C CB  . TYR E 5 101 ? 130.317 147.465 151.367 1.00 34.91  ? 101 TYR S CB  1 
ATOM 7633 C CG  . TYR E 5 101 ? 130.757 148.864 151.733 1.00 35.90  ? 101 TYR S CG  1 
ATOM 7634 C CD1 . TYR E 5 101 ? 130.029 149.625 152.635 1.00 40.68  ? 101 TYR S CD1 1 
ATOM 7635 C CD2 . TYR E 5 101 ? 131.891 149.428 151.169 1.00 43.14  ? 101 TYR S CD2 1 
ATOM 7636 C CE1 . TYR E 5 101 ? 130.421 150.905 152.967 1.00 38.98  ? 101 TYR S CE1 1 
ATOM 7637 C CE2 . TYR E 5 101 ? 132.290 150.706 151.497 1.00 44.61  ? 101 TYR S CE2 1 
ATOM 7638 C CZ  . TYR E 5 101 ? 131.552 151.439 152.397 1.00 41.64  ? 101 TYR S CZ  1 
ATOM 7639 O OH  . TYR E 5 101 ? 131.946 152.713 152.728 1.00 53.76  ? 101 TYR S OH  1 
ATOM 7640 N N   . TYR E 5 102 ? 129.275 144.453 152.680 1.00 37.80  ? 102 TYR S N   1 
ATOM 7641 C CA  . TYR E 5 102 ? 128.437 143.335 152.263 1.00 40.01  ? 102 TYR S CA  1 
ATOM 7642 C C   . TYR E 5 102 ? 127.269 143.274 153.240 1.00 43.99  ? 102 TYR S C   1 
ATOM 7643 O O   . TYR E 5 102 ? 127.087 144.176 154.064 1.00 46.13  ? 102 TYR S O   1 
ATOM 7644 C CB  . TYR E 5 102 ? 129.225 142.020 152.188 1.00 38.79  ? 102 TYR S CB  1 
ATOM 7645 C CG  . TYR E 5 102 ? 130.007 141.652 153.427 1.00 32.59  ? 102 TYR S CG  1 
ATOM 7646 C CD1 . TYR E 5 102 ? 129.399 140.996 154.486 1.00 35.00  ? 102 TYR S CD1 1 
ATOM 7647 C CD2 . TYR E 5 102 ? 131.359 141.937 153.527 1.00 44.92  ? 102 TYR S CD2 1 
ATOM 7648 C CE1 . TYR E 5 102 ? 130.111 140.650 155.614 1.00 38.75  ? 102 TYR S CE1 1 
ATOM 7649 C CE2 . TYR E 5 102 ? 132.078 141.594 154.652 1.00 36.41  ? 102 TYR S CE2 1 
ATOM 7650 C CZ  . TYR E 5 102 ? 131.449 140.953 155.691 1.00 35.21  ? 102 TYR S CZ  1 
ATOM 7651 O OH  . TYR E 5 102 ? 132.162 140.608 156.815 1.00 49.63  ? 102 TYR S OH  1 
ATOM 7652 N N   . TYR E 5 103 ? 126.471 142.216 153.153 1.00 41.65  ? 103 TYR S N   1 
ATOM 7653 C CA  . TYR E 5 103 ? 125.283 142.108 153.996 1.00 30.32  ? 103 TYR S CA  1 
ATOM 7654 C C   . TYR E 5 103 ? 125.710 141.861 155.437 1.00 38.01  ? 103 TYR S C   1 
ATOM 7655 O O   . TYR E 5 103 ? 126.108 140.753 155.801 1.00 47.77  ? 103 TYR S O   1 
ATOM 7656 C CB  . TYR E 5 103 ? 124.368 140.997 153.497 1.00 27.20  ? 103 TYR S CB  1 
ATOM 7657 C CG  . TYR E 5 103 ? 123.156 140.791 154.371 1.00 30.83  ? 103 TYR S CG  1 
ATOM 7658 C CD1 . TYR E 5 103 ? 122.142 141.736 154.414 1.00 36.57  ? 103 TYR S CD1 1 
ATOM 7659 C CD2 . TYR E 5 103 ? 123.029 139.659 155.161 1.00 37.09  ? 103 TYR S CD2 1 
ATOM 7660 C CE1 . TYR E 5 103 ? 121.033 141.557 155.214 1.00 39.70  ? 103 TYR S CE1 1 
ATOM 7661 C CE2 . TYR E 5 103 ? 121.924 139.472 155.965 1.00 40.39  ? 103 TYR S CE2 1 
ATOM 7662 C CZ  . TYR E 5 103 ? 120.930 140.424 155.988 1.00 43.47  ? 103 TYR S CZ  1 
ATOM 7663 O OH  . TYR E 5 103 ? 119.826 140.242 156.787 1.00 48.71  ? 103 TYR S OH  1 
ATOM 7664 N N   . GLY E 5 104 ? 125.623 142.896 156.268 1.00 22.12  ? 104 GLY S N   1 
ATOM 7665 C CA  . GLY E 5 104 ? 125.925 142.762 157.678 1.00 18.19  ? 104 GLY S CA  1 
ATOM 7666 C C   . GLY E 5 104 ? 127.343 143.084 158.083 1.00 28.19  ? 104 GLY S C   1 
ATOM 7667 O O   . GLY E 5 104 ? 127.812 142.561 159.100 1.00 40.94  ? 104 GLY S O   1 
ATOM 7668 N N   . SER E 5 105 ? 128.045 143.922 157.329 1.00 23.45  ? 105 SER S N   1 
ATOM 7669 C CA  . SER E 5 105 ? 129.423 144.273 157.631 1.00 29.85  ? 105 SER S CA  1 
ATOM 7670 C C   . SER E 5 105 ? 129.490 145.581 158.413 1.00 36.05  ? 105 SER S C   1 
ATOM 7671 O O   . SER E 5 105 ? 128.516 146.328 158.517 1.00 41.90  ? 105 SER S O   1 
ATOM 7672 C CB  . SER E 5 105 ? 130.243 144.378 156.343 1.00 29.31  ? 105 SER S CB  1 
ATOM 7673 O OG  . SER E 5 105 ? 129.673 145.320 155.454 1.00 35.19  ? 105 SER S OG  1 
ATOM 7674 N N   . SER E 5 106 ? 130.673 145.853 158.964 1.00 32.87  ? 106 SER S N   1 
ATOM 7675 C CA  . SER E 5 106 ? 130.926 147.065 159.736 1.00 27.64  ? 106 SER S CA  1 
ATOM 7676 C C   . SER E 5 106 ? 131.862 147.967 158.943 1.00 31.32  ? 106 SER S C   1 
ATOM 7677 O O   . SER E 5 106 ? 133.084 147.753 158.948 1.00 50.51  ? 106 SER S O   1 
ATOM 7678 C CB  . SER E 5 106 ? 131.537 146.717 161.096 1.00 37.98  ? 106 SER S CB  1 
ATOM 7679 O OG  . SER E 5 106 ? 131.919 147.884 161.798 1.00 52.09  ? 106 SER S OG  1 
ATOM 7680 N N   . PRO E 5 107 ? 131.349 148.984 158.256 1.00 22.59  ? 107 PRO S N   1 
ATOM 7681 C CA  . PRO E 5 107 ? 132.158 149.680 157.248 1.00 46.84  ? 107 PRO S CA  1 
ATOM 7682 C C   . PRO E 5 107 ? 132.944 150.889 157.736 1.00 47.16  ? 107 PRO S C   1 
ATOM 7683 O O   . PRO E 5 107 ? 133.437 151.661 156.913 1.00 50.69  ? 107 PRO S O   1 
ATOM 7684 C CB  . PRO E 5 107 ? 131.110 150.096 156.212 1.00 34.65  ? 107 PRO S CB  1 
ATOM 7685 C CG  . PRO E 5 107 ? 129.868 150.282 156.997 1.00 35.68  ? 107 PRO S CG  1 
ATOM 7686 C CD  . PRO E 5 107 ? 129.948 149.431 158.240 1.00 39.15  ? 107 PRO S CD  1 
ATOM 7687 N N   . PHE E 5 108 ? 133.051 151.108 159.043 1.00 30.13  ? 108 PHE S N   1 
ATOM 7688 C CA  . PHE E 5 108 ? 133.904 152.194 159.516 1.00 22.30  ? 108 PHE S CA  1 
ATOM 7689 C C   . PHE E 5 108 ? 134.633 151.806 160.796 1.00 34.64  ? 108 PHE S C   1 
ATOM 7690 O O   . PHE E 5 108 ? 134.892 152.659 161.651 1.00 41.97  ? 108 PHE S O   1 
ATOM 7691 C CB  . PHE E 5 108 ? 133.092 153.474 159.708 1.00 43.24  ? 108 PHE S CB  1 
ATOM 7692 C CG  . PHE E 5 108 ? 133.098 154.377 158.504 1.00 38.89  ? 108 PHE S CG  1 
ATOM 7693 C CD1 . PHE E 5 108 ? 134.137 155.264 158.291 1.00 35.38  ? 108 PHE S CD1 1 
ATOM 7694 C CD2 . PHE E 5 108 ? 132.078 154.318 157.571 1.00 36.87  ? 108 PHE S CD2 1 
ATOM 7695 C CE1 . PHE E 5 108 ? 134.148 156.089 157.185 1.00 30.74  ? 108 PHE S CE1 1 
ATOM 7696 C CE2 . PHE E 5 108 ? 132.089 155.136 156.461 1.00 32.15  ? 108 PHE S CE2 1 
ATOM 7697 C CZ  . PHE E 5 108 ? 133.123 156.023 156.269 1.00 31.91  ? 108 PHE S CZ  1 
ATOM 7698 N N   . ASP E 5 109 ? 134.975 150.525 160.934 1.00 45.02  ? 109 ASP S N   1 
ATOM 7699 C CA  . ASP E 5 109 ? 135.402 149.992 162.224 1.00 44.41  ? 109 ASP S CA  1 
ATOM 7700 C C   . ASP E 5 109 ? 136.761 150.533 162.661 1.00 48.12  ? 109 ASP S C   1 
ATOM 7701 O O   . ASP E 5 109 ? 136.931 150.910 163.826 1.00 50.57  ? 109 ASP S O   1 
ATOM 7702 C CB  . ASP E 5 109 ? 135.417 148.467 162.165 1.00 38.33  ? 109 ASP S CB  1 
ATOM 7703 C CG  . ASP E 5 109 ? 136.008 147.945 160.874 1.00 52.11  ? 109 ASP S CG  1 
ATOM 7704 O OD1 . ASP E 5 109 ? 136.367 148.772 160.012 1.00 53.55  ? 109 ASP S OD1 1 
ATOM 7705 O OD2 . ASP E 5 109 ? 136.105 146.711 160.716 1.00 63.06  ? 109 ASP S OD2 1 
ATOM 7706 N N   . PHE E 5 110 ? 137.740 150.577 161.762 1.00 51.17  ? 110 PHE S N   1 
ATOM 7707 C CA  . PHE E 5 110 ? 139.109 150.905 162.138 1.00 46.53  ? 110 PHE S CA  1 
ATOM 7708 C C   . PHE E 5 110 ? 139.550 152.214 161.502 1.00 46.06  ? 110 PHE S C   1 
ATOM 7709 O O   . PHE E 5 110 ? 139.302 152.456 160.317 1.00 60.40  ? 110 PHE S O   1 
ATOM 7710 C CB  . PHE E 5 110 ? 140.078 149.793 161.743 1.00 52.17  ? 110 PHE S CB  1 
ATOM 7711 C CG  . PHE E 5 110 ? 141.329 149.761 162.571 1.00 59.42  ? 110 PHE S CG  1 
ATOM 7712 C CD1 . PHE E 5 110 ? 141.289 149.344 163.891 1.00 55.95  ? 110 PHE S CD1 1 
ATOM 7713 C CD2 . PHE E 5 110 ? 142.544 150.147 162.034 1.00 58.94  ? 110 PHE S CD2 1 
ATOM 7714 C CE1 . PHE E 5 110 ? 142.435 149.313 164.658 1.00 53.67  ? 110 PHE S CE1 1 
ATOM 7715 C CE2 . PHE E 5 110 ? 143.694 150.118 162.798 1.00 58.48  ? 110 PHE S CE2 1 
ATOM 7716 C CZ  . PHE E 5 110 ? 143.639 149.701 164.111 1.00 55.55  ? 110 PHE S CZ  1 
ATOM 7717 N N   . TRP E 5 111 ? 140.218 153.046 162.297 1.00 51.85  ? 111 TRP S N   1 
ATOM 7718 C CA  . TRP E 5 111 ? 140.702 154.348 161.869 1.00 50.28  ? 111 TRP S CA  1 
ATOM 7719 C C   . TRP E 5 111 ? 142.210 154.432 162.055 1.00 47.00  ? 111 TRP S C   1 
ATOM 7720 O O   . TRP E 5 111 ? 142.773 153.829 162.973 1.00 51.98  ? 111 TRP S O   1 
ATOM 7721 C CB  . TRP E 5 111 ? 140.024 155.476 162.654 1.00 46.31  ? 111 TRP S CB  1 
ATOM 7722 C CG  . TRP E 5 111 ? 138.614 155.739 162.235 1.00 44.88  ? 111 TRP S CG  1 
ATOM 7723 C CD1 . TRP E 5 111 ? 137.596 154.837 162.170 1.00 47.20  ? 111 TRP S CD1 1 
ATOM 7724 C CD2 . TRP E 5 111 ? 138.065 156.994 161.823 1.00 43.64  ? 111 TRP S CD2 1 
ATOM 7725 N NE1 . TRP E 5 111 ? 136.446 155.451 161.742 1.00 49.26  ? 111 TRP S NE1 1 
ATOM 7726 C CE2 . TRP E 5 111 ? 136.708 156.776 161.521 1.00 50.89  ? 111 TRP S CE2 1 
ATOM 7727 C CE3 . TRP E 5 111 ? 138.590 158.280 161.678 1.00 51.01  ? 111 TRP S CE3 1 
ATOM 7728 C CZ2 . TRP E 5 111 ? 135.869 157.796 161.085 1.00 54.92  ? 111 TRP S CZ2 1 
ATOM 7729 C CZ3 . TRP E 5 111 ? 137.756 159.291 161.245 1.00 52.56  ? 111 TRP S CZ3 1 
ATOM 7730 C CH2 . TRP E 5 111 ? 136.411 159.044 160.953 1.00 51.78  ? 111 TRP S CH2 1 
ATOM 7731 N N   . GLY E 5 112 ? 142.860 155.186 161.177 1.00 57.30  ? 112 GLY S N   1 
ATOM 7732 C CA  . GLY E 5 112 ? 144.291 155.376 161.274 1.00 59.99  ? 112 GLY S CA  1 
ATOM 7733 C C   . GLY E 5 112 ? 144.674 156.296 162.417 1.00 62.92  ? 112 GLY S C   1 
ATOM 7734 O O   . GLY E 5 112 ? 143.847 156.978 163.024 1.00 69.64  ? 112 GLY S O   1 
ATOM 7735 N N   . GLN E 5 113 ? 145.975 156.311 162.715 1.00 70.50  ? 113 GLN S N   1 
ATOM 7736 C CA  . GLN E 5 113 ? 146.474 157.119 163.822 1.00 77.45  ? 113 GLN S CA  1 
ATOM 7737 C C   . GLN E 5 113 ? 146.437 158.612 163.521 1.00 81.09  ? 113 GLN S C   1 
ATOM 7738 O O   . GLN E 5 113 ? 146.529 159.419 164.452 1.00 84.12  ? 113 GLN S O   1 
ATOM 7739 C CB  . GLN E 5 113 ? 147.899 156.700 164.184 1.00 77.60  ? 113 GLN S CB  1 
ATOM 7740 C CG  . GLN E 5 113 ? 148.944 157.085 163.150 1.00 80.41  ? 113 GLN S CG  1 
ATOM 7741 C CD  . GLN E 5 113 ? 150.359 156.992 163.689 1.00 83.31  ? 113 GLN S CD  1 
ATOM 7742 O OE1 . GLN E 5 113 ? 150.612 156.319 164.688 1.00 80.32  ? 113 GLN S OE1 1 
ATOM 7743 N NE2 . GLN E 5 113 ? 151.290 157.670 163.028 1.00 84.15  ? 113 GLN S NE2 1 
ATOM 7744 N N   . GLY E 5 114 ? 146.309 158.998 162.254 1.00 75.14  ? 114 GLY S N   1 
ATOM 7745 C CA  . GLY E 5 114 ? 146.237 160.403 161.903 1.00 75.79  ? 114 GLY S CA  1 
ATOM 7746 C C   . GLY E 5 114 ? 147.585 161.015 161.585 1.00 76.23  ? 114 GLY S C   1 
ATOM 7747 O O   . GLY E 5 114 ? 148.559 160.799 162.311 1.00 75.03  ? 114 GLY S O   1 
ATOM 7748 N N   . THR E 5 115 ? 147.653 161.782 160.500 1.00 75.74  ? 115 THR S N   1 
ATOM 7749 C CA  . THR E 5 115 ? 148.848 162.528 160.131 1.00 77.85  ? 115 THR S CA  1 
ATOM 7750 C C   . THR E 5 115 ? 148.501 164.007 160.025 1.00 79.37  ? 115 THR S C   1 
ATOM 7751 O O   . THR E 5 115 ? 147.452 164.372 159.485 1.00 81.72  ? 115 THR S O   1 
ATOM 7752 C CB  . THR E 5 115 ? 149.449 162.021 158.811 1.00 76.61  ? 115 THR S CB  1 
ATOM 7753 O OG1 . THR E 5 115 ? 150.586 162.820 158.462 1.00 77.69  ? 115 THR S OG1 1 
ATOM 7754 C CG2 . THR E 5 115 ? 148.427 162.073 157.684 1.00 76.52  ? 115 THR S CG2 1 
ATOM 7755 N N   . THR E 5 116 ? 149.377 164.855 160.555 1.00 77.15  ? 116 THR S N   1 
ATOM 7756 C CA  . THR E 5 116 ? 149.125 166.288 160.609 1.00 77.02  ? 116 THR S CA  1 
ATOM 7757 C C   . THR E 5 116 ? 149.774 166.978 159.418 1.00 75.47  ? 116 THR S C   1 
ATOM 7758 O O   . THR E 5 116 ? 150.973 166.812 159.173 1.00 79.02  ? 116 THR S O   1 
ATOM 7759 C CB  . THR E 5 116 ? 149.653 166.884 161.914 1.00 75.21  ? 116 THR S CB  1 
ATOM 7760 O OG1 . THR E 5 116 ? 148.984 166.274 163.024 1.00 76.65  ? 116 THR S OG1 1 
ATOM 7761 C CG2 . THR E 5 116 ? 149.410 168.384 161.948 1.00 71.49  ? 116 THR S CG2 1 
ATOM 7762 N N   . LEU E 5 117 ? 148.980 167.752 158.684 1.00 75.87  ? 117 LEU S N   1 
ATOM 7763 C CA  . LEU E 5 117 ? 149.455 168.516 157.541 1.00 76.42  ? 117 LEU S CA  1 
ATOM 7764 C C   . LEU E 5 117 ? 149.150 169.988 157.773 1.00 75.73  ? 117 LEU S C   1 
ATOM 7765 O O   . LEU E 5 117 ? 148.013 170.347 158.093 1.00 76.08  ? 117 LEU S O   1 
ATOM 7766 C CB  . LEU E 5 117 ? 148.807 168.023 156.244 1.00 76.27  ? 117 LEU S CB  1 
ATOM 7767 C CG  . LEU E 5 117 ? 149.219 168.707 154.940 1.00 76.49  ? 117 LEU S CG  1 
ATOM 7768 C CD1 . LEU E 5 117 ? 149.278 167.680 153.835 1.00 75.17  ? 117 LEU S CD1 1 
ATOM 7769 C CD2 . LEU E 5 117 ? 148.249 169.815 154.566 1.00 76.53  ? 117 LEU S CD2 1 
ATOM 7770 N N   . THR E 5 118 ? 150.164 170.833 157.610 1.00 88.93  ? 118 THR S N   1 
ATOM 7771 C CA  . THR E 5 118 ? 150.047 172.262 157.855 1.00 89.89  ? 118 THR S CA  1 
ATOM 7772 C C   . THR E 5 118 ? 150.427 173.033 156.600 1.00 89.22  ? 118 THR S C   1 
ATOM 7773 O O   . THR E 5 118 ? 151.407 172.698 155.927 1.00 92.31  ? 118 THR S O   1 
ATOM 7774 C CB  . THR E 5 118 ? 150.939 172.698 159.023 1.00 89.81  ? 118 THR S CB  1 
ATOM 7775 O OG1 . THR E 5 118 ? 150.732 171.822 160.138 1.00 87.86  ? 118 THR S OG1 1 
ATOM 7776 C CG2 . THR E 5 118 ? 150.613 174.122 159.442 1.00 89.12  ? 118 THR S CG2 1 
ATOM 7777 N N   . VAL E 5 119 ? 149.647 174.063 156.288 1.00 91.98  ? 119 VAL S N   1 
ATOM 7778 C CA  . VAL E 5 119 ? 149.912 174.948 155.161 1.00 93.28  ? 119 VAL S CA  1 
ATOM 7779 C C   . VAL E 5 119 ? 150.089 176.357 155.707 1.00 97.40  ? 119 VAL S C   1 
ATOM 7780 O O   . VAL E 5 119 ? 149.194 176.884 156.380 1.00 99.23  ? 119 VAL S O   1 
ATOM 7781 C CB  . VAL E 5 119 ? 148.787 174.903 154.116 1.00 91.44  ? 119 VAL S CB  1 
ATOM 7782 C CG1 . VAL E 5 119 ? 149.082 175.870 152.986 1.00 94.45  ? 119 VAL S CG1 1 
ATOM 7783 C CG2 . VAL E 5 119 ? 148.615 173.491 153.584 1.00 91.70  ? 119 VAL S CG2 1 
ATOM 7784 N N   . SER E 5 120 ? 151.237 176.963 155.421 1.00 111.80 ? 120 SER S N   1 
ATOM 7785 C CA  . SER E 5 120 ? 151.503 178.314 155.886 1.00 111.92 ? 120 SER S CA  1 
ATOM 7786 C C   . SER E 5 120 ? 150.676 179.325 155.097 1.00 112.30 ? 120 SER S C   1 
ATOM 7787 O O   . SER E 5 120 ? 150.247 179.076 153.968 1.00 111.90 ? 120 SER S O   1 
ATOM 7788 C CB  . SER E 5 120 ? 152.991 178.641 155.762 1.00 111.66 ? 120 SER S CB  1 
ATOM 7789 O OG  . SER E 5 120 ? 153.265 179.950 156.231 1.00 112.43 ? 120 SER S OG  1 
ATOM 7790 N N   . SER E 5 121 ? 150.454 180.482 155.713 1.00 119.38 ? 121 SER S N   1 
ATOM 7791 C CA  . SER E 5 121 ? 149.686 181.547 155.079 1.00 120.22 ? 121 SER S CA  1 
ATOM 7792 C C   . SER E 5 121 ? 150.552 182.340 154.106 1.00 119.99 ? 121 SER S C   1 
ATOM 7793 O O   . SER E 5 121 ? 151.714 182.005 153.879 1.00 119.75 ? 121 SER S O   1 
ATOM 7794 C CB  . SER E 5 121 ? 149.090 182.480 156.135 1.00 118.83 ? 121 SER S CB  1 
ATOM 7795 O OG  . SER E 5 121 ? 148.106 181.813 156.906 1.00 118.21 ? 121 SER S OG  1 
ATOM 7796 N N   . SER E 5 136 ? 121.197 170.251 148.304 1.00 119.18 ? 124 SER S N   1 
ATOM 7797 C CA  . SER E 5 136 ? 122.012 169.316 147.538 1.00 119.83 ? 124 SER S CA  1 
ATOM 7798 C C   . SER E 5 136 ? 122.490 168.161 148.412 1.00 118.33 ? 124 SER S C   1 
ATOM 7799 O O   . SER E 5 136 ? 122.041 167.025 148.256 1.00 117.44 ? 124 SER S O   1 
ATOM 7800 C CB  . SER E 5 136 ? 123.210 170.036 146.915 1.00 120.97 ? 124 SER S CB  1 
ATOM 7801 O OG  . SER E 5 136 ? 124.010 170.652 147.909 1.00 120.99 ? 124 SER S OG  1 
ATOM 7802 N N   . ASP E 5 137 ? 123.402 168.458 149.331 1.00 102.18 ? 125 ASP S N   1 
ATOM 7803 C CA  . ASP E 5 137 ? 123.943 167.458 150.237 1.00 99.19  ? 125 ASP S CA  1 
ATOM 7804 C C   . ASP E 5 137 ? 123.060 167.319 151.473 1.00 97.47  ? 125 ASP S C   1 
ATOM 7805 O O   . ASP E 5 137 ? 122.254 168.194 151.797 1.00 98.82  ? 125 ASP S O   1 
ATOM 7806 C CB  . ASP E 5 137 ? 125.369 167.821 150.651 1.00 97.61  ? 125 ASP S CB  1 
ATOM 7807 C CG  . ASP E 5 137 ? 126.310 167.924 149.469 1.00 100.27 ? 125 ASP S CG  1 
ATOM 7808 O OD1 . ASP E 5 137 ? 126.028 167.297 148.427 1.00 99.48  ? 125 ASP S OD1 1 
ATOM 7809 O OD2 . ASP E 5 137 ? 127.332 168.632 149.583 1.00 103.81 ? 125 ASP S OD2 1 
ATOM 7810 N N   . ILE E 5 138 ? 123.226 166.196 152.165 1.00 76.42  ? 126 ILE S N   1 
ATOM 7811 C CA  . ILE E 5 138 ? 122.475 165.933 153.387 1.00 76.66  ? 126 ILE S CA  1 
ATOM 7812 C C   . ILE E 5 138 ? 123.168 166.629 154.549 1.00 77.85  ? 126 ILE S C   1 
ATOM 7813 O O   . ILE E 5 138 ? 124.367 166.433 154.782 1.00 78.29  ? 126 ILE S O   1 
ATOM 7814 C CB  . ILE E 5 138 ? 122.351 164.423 153.634 1.00 77.37  ? 126 ILE S CB  1 
ATOM 7815 C CG1 . ILE E 5 138 ? 121.821 163.724 152.381 1.00 78.10  ? 126 ILE S CG1 1 
ATOM 7816 C CG2 . ILE E 5 138 ? 121.441 164.153 154.819 1.00 79.24  ? 126 ILE S CG2 1 
ATOM 7817 C CD1 . ILE E 5 138 ? 121.656 162.231 152.538 1.00 76.26  ? 126 ILE S CD1 1 
ATOM 7818 N N   . VAL E 5 139 ? 122.417 167.444 155.282 1.00 81.07  ? 127 VAL S N   1 
ATOM 7819 C CA  . VAL E 5 139 ? 122.958 168.256 156.366 1.00 80.94  ? 127 VAL S CA  1 
ATOM 7820 C C   . VAL E 5 139 ? 122.598 167.600 157.691 1.00 80.32  ? 127 VAL S C   1 
ATOM 7821 O O   . VAL E 5 139 ? 121.415 167.424 158.005 1.00 80.93  ? 127 VAL S O   1 
ATOM 7822 C CB  . VAL E 5 139 ? 122.429 169.697 156.304 1.00 80.85  ? 127 VAL S CB  1 
ATOM 7823 C CG1 . VAL E 5 139 ? 122.913 170.492 157.506 1.00 82.56  ? 127 VAL S CG1 1 
ATOM 7824 C CG2 . VAL E 5 139 ? 122.859 170.363 155.007 1.00 79.14  ? 127 VAL S CG2 1 
ATOM 7825 N N   . MET E 5 140 ? 123.615 167.241 158.469 1.00 74.27  ? 128 MET S N   1 
ATOM 7826 C CA  . MET E 5 140 ? 123.432 166.667 159.795 1.00 74.58  ? 128 MET S CA  1 
ATOM 7827 C C   . MET E 5 140 ? 123.785 167.722 160.837 1.00 74.74  ? 128 MET S C   1 
ATOM 7828 O O   . MET E 5 140 ? 124.890 168.274 160.815 1.00 78.53  ? 128 MET S O   1 
ATOM 7829 C CB  . MET E 5 140 ? 124.296 165.421 159.976 1.00 73.02  ? 128 MET S CB  1 
ATOM 7830 C CG  . MET E 5 140 ? 124.389 164.549 158.737 1.00 72.26  ? 128 MET S CG  1 
ATOM 7831 S SD  . MET E 5 140 ? 123.013 163.396 158.616 1.00 75.74  ? 128 MET S SD  1 
ATOM 7832 C CE  . MET E 5 140 ? 123.081 162.634 160.232 1.00 72.93  ? 128 MET S CE  1 
ATOM 7833 N N   . THR E 5 141 ? 122.851 167.997 161.744 1.00 83.03  ? 129 THR S N   1 
ATOM 7834 C CA  . THR E 5 141 ? 123.016 169.033 162.754 1.00 86.78  ? 129 THR S CA  1 
ATOM 7835 C C   . THR E 5 141 ? 122.919 168.415 164.141 1.00 86.29  ? 129 THR S C   1 
ATOM 7836 O O   . THR E 5 141 ? 122.005 167.631 164.412 1.00 86.61  ? 129 THR S O   1 
ATOM 7837 C CB  . THR E 5 141 ? 121.960 170.132 162.601 1.00 85.62  ? 129 THR S CB  1 
ATOM 7838 O OG1 . THR E 5 141 ? 120.793 169.784 163.356 1.00 86.07  ? 129 THR S OG1 1 
ATOM 7839 C CG2 . THR E 5 141 ? 121.574 170.307 161.139 1.00 82.97  ? 129 THR S CG2 1 
ATOM 7840 N N   . GLN E 5 142 ? 123.857 168.773 165.013 1.00 84.84  ? 130 GLN S N   1 
ATOM 7841 C CA  . GLN E 5 142 ? 123.852 168.344 166.404 1.00 83.38  ? 130 GLN S CA  1 
ATOM 7842 C C   . GLN E 5 142 ? 123.444 169.520 167.281 1.00 86.28  ? 130 GLN S C   1 
ATOM 7843 O O   . GLN E 5 142 ? 124.006 170.614 167.160 1.00 88.75  ? 130 GLN S O   1 
ATOM 7844 C CB  . GLN E 5 142 ? 125.222 167.804 166.819 1.00 82.97  ? 130 GLN S CB  1 
ATOM 7845 C CG  . GLN E 5 142 ? 125.596 166.509 166.117 1.00 82.03  ? 130 GLN S CG  1 
ATOM 7846 C CD  . GLN E 5 142 ? 126.670 165.731 166.846 1.00 85.20  ? 130 GLN S CD  1 
ATOM 7847 O OE1 . GLN E 5 142 ? 126.566 165.483 168.047 1.00 88.04  ? 130 GLN S OE1 1 
ATOM 7848 N NE2 . GLN E 5 142 ? 127.705 165.329 166.120 1.00 82.47  ? 130 GLN S NE2 1 
ATOM 7849 N N   . ALA E 5 143 ? 122.463 169.290 168.156 1.00 99.74  ? 131 ALA S N   1 
ATOM 7850 C CA  . ALA E 5 143 ? 121.839 170.388 168.888 1.00 101.76 ? 131 ALA S CA  1 
ATOM 7851 C C   . ALA E 5 143 ? 122.814 171.071 169.841 1.00 104.35 ? 131 ALA S C   1 
ATOM 7852 O O   . ALA E 5 143 ? 122.850 172.305 169.916 1.00 104.04 ? 131 ALA S O   1 
ATOM 7853 C CB  . ALA E 5 143 ? 120.618 169.878 169.652 1.00 100.71 ? 131 ALA S CB  1 
ATOM 7854 N N   . THR E 5 144 ? 123.612 170.298 170.572 1.00 100.21 ? 132 THR S N   1 
ATOM 7855 C CA  . THR E 5 144 ? 124.437 170.829 171.648 1.00 99.10  ? 132 THR S CA  1 
ATOM 7856 C C   . THR E 5 144 ? 125.902 170.510 171.388 1.00 99.80  ? 132 THR S C   1 
ATOM 7857 O O   . THR E 5 144 ? 126.235 169.422 170.906 1.00 101.05 ? 132 THR S O   1 
ATOM 7858 C CB  . THR E 5 144 ? 123.998 170.255 173.004 1.00 98.86  ? 132 THR S CB  1 
ATOM 7859 O OG1 . THR E 5 144 ? 122.656 170.673 173.284 1.00 103.54 ? 132 THR S OG1 1 
ATOM 7860 C CG2 . THR E 5 144 ? 124.901 170.749 174.121 1.00 98.78  ? 132 THR S CG2 1 
ATOM 7861 N N   . SER E 5 145 ? 126.776 171.467 171.708 1.00 102.45 ? 133 SER S N   1 
ATOM 7862 C CA  . SER E 5 145 ? 128.207 171.318 171.482 1.00 103.54 ? 133 SER S CA  1 
ATOM 7863 C C   . SER E 5 145 ? 128.979 170.863 172.715 1.00 103.49 ? 133 SER S C   1 
ATOM 7864 O O   . SER E 5 145 ? 130.100 170.365 172.569 1.00 101.81 ? 133 SER S O   1 
ATOM 7865 C CB  . SER E 5 145 ? 128.803 172.640 170.983 1.00 102.84 ? 133 SER S CB  1 
ATOM 7866 O OG  . SER E 5 145 ? 130.218 172.586 170.957 1.00 104.58 ? 133 SER S OG  1 
ATOM 7867 N N   . SER E 5 146 ? 128.420 171.017 173.914 1.00 110.57 ? 134 SER S N   1 
ATOM 7868 C CA  . SER E 5 146 ? 129.118 170.623 175.131 1.00 110.99 ? 134 SER S CA  1 
ATOM 7869 C C   . SER E 5 146 ? 128.105 170.232 176.196 1.00 112.63 ? 134 SER S C   1 
ATOM 7870 O O   . SER E 5 146 ? 127.169 170.988 176.471 1.00 111.21 ? 134 SER S O   1 
ATOM 7871 C CB  . SER E 5 146 ? 130.016 171.754 175.642 1.00 111.19 ? 134 SER S CB  1 
ATOM 7872 O OG  . SER E 5 146 ? 130.655 171.390 176.853 1.00 111.31 ? 134 SER S OG  1 
ATOM 7873 N N   . VAL E 5 147 ? 128.299 169.059 176.794 1.00 120.48 ? 135 VAL S N   1 
ATOM 7874 C CA  . VAL E 5 147 ? 127.400 168.550 177.828 1.00 119.18 ? 135 VAL S CA  1 
ATOM 7875 C C   . VAL E 5 147 ? 128.211 168.097 179.037 1.00 117.93 ? 135 VAL S C   1 
ATOM 7876 O O   . VAL E 5 147 ? 128.914 167.078 178.964 1.00 116.59 ? 135 VAL S O   1 
ATOM 7877 C CB  . VAL E 5 147 ? 126.530 167.399 177.298 1.00 118.06 ? 135 VAL S CB  1 
ATOM 7878 C CG1 . VAL E 5 147 ? 125.736 166.769 178.431 1.00 117.09 ? 135 VAL S CG1 1 
ATOM 7879 C CG2 . VAL E 5 147 ? 125.596 167.892 176.207 1.00 116.78 ? 135 VAL S CG2 1 
ATOM 7880 N N   . PRO E 5 148 ? 128.159 168.816 180.157 1.00 124.01 ? 136 PRO S N   1 
ATOM 7881 C CA  . PRO E 5 148 ? 128.808 168.327 181.379 1.00 124.79 ? 136 PRO S CA  1 
ATOM 7882 C C   . PRO E 5 148 ? 127.927 167.321 182.102 1.00 124.78 ? 136 PRO S C   1 
ATOM 7883 O O   . PRO E 5 148 ? 126.702 167.454 182.144 1.00 126.11 ? 136 PRO S O   1 
ATOM 7884 C CB  . PRO E 5 148 ? 129.002 169.600 182.218 1.00 123.40 ? 136 PRO S CB  1 
ATOM 7885 C CG  . PRO E 5 148 ? 128.522 170.753 181.356 1.00 122.64 ? 136 PRO S CG  1 
ATOM 7886 C CD  . PRO E 5 148 ? 127.610 170.168 180.331 1.00 122.10 ? 136 PRO S CD  1 
ATOM 7887 N N   . VAL E 5 149 ? 128.567 166.305 182.682 1.00 121.27 ? 137 VAL S N   1 
ATOM 7888 C CA  . VAL E 5 149 ? 127.847 165.248 183.382 1.00 122.06 ? 137 VAL S CA  1 
ATOM 7889 C C   . VAL E 5 149 ? 128.823 164.541 184.311 1.00 123.75 ? 137 VAL S C   1 
ATOM 7890 O O   . VAL E 5 149 ? 130.037 164.561 184.092 1.00 122.14 ? 137 VAL S O   1 
ATOM 7891 C CB  . VAL E 5 149 ? 127.186 164.264 182.382 1.00 122.41 ? 137 VAL S CB  1 
ATOM 7892 C CG1 . VAL E 5 149 ? 128.237 163.385 181.720 1.00 123.25 ? 137 VAL S CG1 1 
ATOM 7893 C CG2 . VAL E 5 149 ? 126.114 163.428 183.071 1.00 122.00 ? 137 VAL S CG2 1 
ATOM 7894 N N   . THR E 5 150 ? 128.276 163.910 185.377 1.00 120.35 ? 138 THR S N   1 
ATOM 7895 C CA  . THR E 5 150 ? 128.965 163.127 186.387 1.00 117.99 ? 138 THR S CA  1 
ATOM 7896 C C   . THR E 5 150 ? 128.870 161.639 186.066 1.00 117.84 ? 138 THR S C   1 
ATOM 7897 O O   . THR E 5 150 ? 127.928 161.202 185.397 1.00 116.76 ? 138 THR S O   1 
ATOM 7898 C CB  . THR E 5 150 ? 128.365 163.386 187.773 1.00 117.85 ? 138 THR S CB  1 
ATOM 7899 N N   . PRO E 5 151 ? 129.834 160.834 186.518 1.00 114.48 ? 139 PRO S N   1 
ATOM 7900 C CA  . PRO E 5 151 ? 129.780 159.395 186.235 1.00 114.65 ? 139 PRO S CA  1 
ATOM 7901 C C   . PRO E 5 151 ? 128.559 158.742 186.864 1.00 115.26 ? 139 PRO S C   1 
ATOM 7902 O O   . PRO E 5 151 ? 128.077 159.157 187.921 1.00 114.80 ? 139 PRO S O   1 
ATOM 7903 C CB  . PRO E 5 151 ? 131.079 158.861 186.852 1.00 112.63 ? 139 PRO S CB  1 
ATOM 7904 C CG  . PRO E 5 151 ? 131.981 160.047 186.928 1.00 113.27 ? 139 PRO S CG  1 
ATOM 7905 C CD  . PRO E 5 151 ? 131.084 161.216 187.196 1.00 113.55 ? 139 PRO S CD  1 
ATOM 7906 N N   . GLY E 5 152 ? 128.059 157.705 186.195 1.00 114.21 ? 140 GLY S N   1 
ATOM 7907 C CA  . GLY E 5 152 ? 126.893 156.983 186.652 1.00 112.12 ? 140 GLY S CA  1 
ATOM 7908 C C   . GLY E 5 152 ? 125.565 157.551 186.205 1.00 112.81 ? 140 GLY S C   1 
ATOM 7909 O O   . GLY E 5 152 ? 124.521 156.979 186.546 1.00 115.94 ? 140 GLY S O   1 
ATOM 7910 N N   . GLU E 5 153 ? 125.564 158.650 185.457 1.00 116.41 ? 141 GLU S N   1 
ATOM 7911 C CA  . GLU E 5 153 ? 124.343 159.288 184.985 1.00 117.68 ? 141 GLU S CA  1 
ATOM 7912 C C   . GLU E 5 153 ? 124.205 159.075 183.484 1.00 117.76 ? 141 GLU S C   1 
ATOM 7913 O O   . GLU E 5 153 ? 125.159 159.300 182.731 1.00 116.79 ? 141 GLU S O   1 
ATOM 7914 C CB  . GLU E 5 153 ? 124.344 160.783 185.310 1.00 117.47 ? 141 GLU S CB  1 
ATOM 7915 N N   . SER E 5 154 ? 123.023 158.638 183.057 1.00 116.67 ? 142 SER S N   1 
ATOM 7916 C CA  . SER E 5 154 ? 122.774 158.411 181.641 1.00 117.36 ? 142 SER S CA  1 
ATOM 7917 C C   . SER E 5 154 ? 122.781 159.729 180.875 1.00 115.56 ? 142 SER S C   1 
ATOM 7918 O O   . SER E 5 154 ? 122.291 160.752 181.361 1.00 111.95 ? 142 SER S O   1 
ATOM 7919 C CB  . SER E 5 154 ? 121.440 157.694 181.444 1.00 114.97 ? 142 SER S CB  1 
ATOM 7920 O OG  . SER E 5 154 ? 121.356 156.541 182.264 1.00 115.33 ? 142 SER S OG  1 
ATOM 7921 N N   . VAL E 5 155 ? 123.341 159.696 179.669 1.00 109.96 ? 143 VAL S N   1 
ATOM 7922 C CA  . VAL E 5 155 ? 123.453 160.868 178.810 1.00 109.24 ? 143 VAL S CA  1 
ATOM 7923 C C   . VAL E 5 155 ? 122.751 160.578 177.493 1.00 107.74 ? 143 VAL S C   1 
ATOM 7924 O O   . VAL E 5 155 ? 122.838 159.465 176.963 1.00 106.28 ? 143 VAL S O   1 
ATOM 7925 C CB  . VAL E 5 155 ? 124.925 161.259 178.568 1.00 107.71 ? 143 VAL S CB  1 
ATOM 7926 C CG1 . VAL E 5 155 ? 125.445 162.093 179.721 1.00 108.20 ? 143 VAL S CG1 1 
ATOM 7927 C CG2 . VAL E 5 155 ? 125.777 160.017 178.382 1.00 107.17 ? 143 VAL S CG2 1 
ATOM 7928 N N   . SER E 5 156 ? 122.052 161.581 176.970 1.00 92.87  ? 144 SER S N   1 
ATOM 7929 C CA  . SER E 5 156 ? 121.339 161.474 175.705 1.00 91.91  ? 144 SER S CA  1 
ATOM 7930 C C   . SER E 5 156 ? 121.962 162.425 174.694 1.00 91.87  ? 144 SER S C   1 
ATOM 7931 O O   . SER E 5 156 ? 122.082 163.626 174.957 1.00 91.43  ? 144 SER S O   1 
ATOM 7932 C CB  . SER E 5 156 ? 119.852 161.787 175.884 1.00 91.60  ? 144 SER S CB  1 
ATOM 7933 O OG  . SER E 5 156 ? 119.179 161.796 174.638 1.00 91.71  ? 144 SER S OG  1 
ATOM 7934 N N   . ILE E 5 157 ? 122.358 161.886 173.544 1.00 83.82  ? 145 ILE S N   1 
ATOM 7935 C CA  . ILE E 5 157 ? 122.925 162.663 172.448 1.00 79.54  ? 145 ILE S CA  1 
ATOM 7936 C C   . ILE E 5 157 ? 122.055 162.448 171.220 1.00 81.49  ? 145 ILE S C   1 
ATOM 7937 O O   . ILE E 5 157 ? 121.749 161.305 170.863 1.00 83.37  ? 145 ILE S O   1 
ATOM 7938 C CB  . ILE E 5 157 ? 124.385 162.266 172.163 1.00 77.71  ? 145 ILE S CB  1 
ATOM 7939 C CG1 . ILE E 5 157 ? 125.171 162.154 173.470 1.00 81.78  ? 145 ILE S CG1 1 
ATOM 7940 C CG2 . ILE E 5 157 ? 125.036 163.271 171.228 1.00 78.57  ? 145 ILE S CG2 1 
ATOM 7941 C CD1 . ILE E 5 157 ? 126.613 161.751 173.282 1.00 79.50  ? 145 ILE S CD1 1 
ATOM 7942 N N   . SER E 5 158 ? 121.655 163.544 170.578 1.00 82.08  ? 146 SER S N   1 
ATOM 7943 C CA  . SER E 5 158 ? 120.743 163.480 169.446 1.00 81.55  ? 146 SER S CA  1 
ATOM 7944 C C   . SER E 5 158 ? 121.233 164.384 168.327 1.00 82.23  ? 146 SER S C   1 
ATOM 7945 O O   . SER E 5 158 ? 121.789 165.456 168.582 1.00 86.02  ? 146 SER S O   1 
ATOM 7946 C CB  . SER E 5 158 ? 119.322 163.887 169.856 1.00 83.28  ? 146 SER S CB  1 
ATOM 7947 O OG  . SER E 5 158 ? 119.250 165.274 170.138 1.00 84.53  ? 146 SER S OG  1 
ATOM 7948 N N   . CYS E 5 159 ? 121.025 163.945 167.086 1.00 85.76  ? 147 CYS S N   1 
ATOM 7949 C CA  . CYS E 5 159 ? 121.313 164.760 165.916 1.00 88.36  ? 147 CYS S CA  1 
ATOM 7950 C C   . CYS E 5 159 ? 120.290 164.457 164.831 1.00 86.81  ? 147 CYS S C   1 
ATOM 7951 O O   . CYS E 5 159 ? 119.853 163.316 164.668 1.00 86.96  ? 147 CYS S O   1 
ATOM 7952 C CB  . CYS E 5 159 ? 122.738 164.528 165.387 1.00 88.16  ? 147 CYS S CB  1 
ATOM 7953 S SG  . CYS E 5 159 ? 123.044 162.938 164.584 1.00 97.38  ? 147 CYS S SG  1 
ATOM 7954 N N   . ARG E 5 160 ? 119.915 165.494 164.092 1.00 92.36  ? 148 ARG S N   1 
ATOM 7955 C CA  . ARG E 5 160 ? 118.901 165.402 163.053 1.00 91.53  ? 148 ARG S CA  1 
ATOM 7956 C C   . ARG E 5 160 ? 119.546 165.333 161.672 1.00 92.03  ? 148 ARG S C   1 
ATOM 7957 O O   . ARG E 5 160 ? 120.738 165.594 161.496 1.00 97.85  ? 148 ARG S O   1 
ATOM 7958 C CB  . ARG E 5 160 ? 117.941 166.595 163.144 1.00 91.54  ? 148 ARG S CB  1 
ATOM 7959 C CG  . ARG E 5 160 ? 118.224 167.713 162.150 1.00 91.95  ? 148 ARG S CG  1 
ATOM 7960 C CD  . ARG E 5 160 ? 117.016 168.615 161.961 1.00 94.15  ? 148 ARG S CD  1 
ATOM 7961 N NE  . ARG E 5 160 ? 116.334 168.892 163.220 1.00 95.88  ? 148 ARG S NE  1 
ATOM 7962 C CZ  . ARG E 5 160 ? 116.459 170.020 163.906 1.00 95.74  ? 148 ARG S CZ  1 
ATOM 7963 N NH1 . ARG E 5 160 ? 117.236 171.004 163.483 1.00 94.86  ? 148 ARG S NH1 1 
ATOM 7964 N NH2 . ARG E 5 160 ? 115.787 170.164 165.045 1.00 94.08  ? 148 ARG S NH2 1 
ATOM 7965 N N   . SER E 5 161 ? 118.732 164.974 160.681 1.00 84.20  ? 149 SER S N   1 
ATOM 7966 C CA  . SER E 5 161 ? 119.168 164.924 159.294 1.00 85.79  ? 149 SER S CA  1 
ATOM 7967 C C   . SER E 5 161 ? 118.128 165.608 158.421 1.00 89.29  ? 149 SER S C   1 
ATOM 7968 O O   . SER E 5 161 ? 116.941 165.644 158.757 1.00 88.11  ? 149 SER S O   1 
ATOM 7969 C CB  . SER E 5 161 ? 119.385 163.482 158.820 1.00 87.90  ? 149 SER S CB  1 
ATOM 7970 O OG  . SER E 5 161 ? 118.148 162.829 158.599 1.00 92.79  ? 149 SER S OG  1 
ATOM 7971 N N   . SER E 5 162 ? 118.586 166.155 157.294 1.00 93.26  ? 150 SER S N   1 
ATOM 7972 C CA  . SER E 5 162 ? 117.680 166.853 156.387 1.00 92.39  ? 150 SER S CA  1 
ATOM 7973 C C   . SER E 5 162 ? 116.721 165.877 155.717 1.00 93.97  ? 150 SER S C   1 
ATOM 7974 O O   . SER E 5 162 ? 115.499 165.979 155.873 1.00 97.10  ? 150 SER S O   1 
ATOM 7975 C CB  . SER E 5 162 ? 118.481 167.631 155.342 1.00 90.45  ? 150 SER S CB  1 
ATOM 7976 O OG  . SER E 5 162 ? 119.330 168.583 155.958 1.00 93.11  ? 150 SER S OG  1 
ATOM 7977 N N   . LYS E 5 163 ? 117.258 164.921 154.964 1.00 91.07  ? 151 LYS S N   1 
ATOM 7978 C CA  . LYS E 5 163 ? 116.430 163.893 154.360 1.00 92.70  ? 151 LYS S CA  1 
ATOM 7979 C C   . LYS E 5 163 ? 116.135 162.787 155.368 1.00 96.13  ? 151 LYS S C   1 
ATOM 7980 O O   . LYS E 5 163 ? 116.669 162.758 156.480 1.00 96.49  ? 151 LYS S O   1 
ATOM 7981 C CB  . LYS E 5 163 ? 117.110 163.309 153.122 1.00 88.14  ? 151 LYS S CB  1 
ATOM 7982 C CG  . LYS E 5 163 ? 117.281 164.290 151.979 1.00 91.45  ? 151 LYS S CG  1 
ATOM 7983 C CD  . LYS E 5 163 ? 117.853 163.597 150.754 1.00 91.12  ? 151 LYS S CD  1 
ATOM 7984 C CE  . LYS E 5 163 ? 117.086 162.322 150.436 1.00 91.17  ? 151 LYS S CE  1 
ATOM 7985 N NZ  . LYS E 5 163 ? 117.415 161.790 149.085 1.00 93.53  ? 151 LYS S NZ  1 
ATOM 7986 N N   . SER E 5 164 ? 115.265 161.865 154.966 1.00 92.15  ? 152 SER S N   1 
ATOM 7987 C CA  . SER E 5 164 ? 114.972 160.678 155.758 1.00 89.97  ? 152 SER S CA  1 
ATOM 7988 C C   . SER E 5 164 ? 115.933 159.577 155.330 1.00 90.30  ? 152 SER S C   1 
ATOM 7989 O O   . SER E 5 164 ? 115.833 159.054 154.215 1.00 89.17  ? 152 SER S O   1 
ATOM 7990 C CB  . SER E 5 164 ? 113.519 160.247 155.576 1.00 90.30  ? 152 SER S CB  1 
ATOM 7991 O OG  . SER E 5 164 ? 113.128 159.338 156.590 1.00 89.11  ? 152 SER S OG  1 
ATOM 7992 N N   . LEU E 5 165 ? 116.869 159.228 156.214 1.00 76.59  ? 153 LEU S N   1 
ATOM 7993 C CA  . LEU E 5 165 ? 117.879 158.228 155.892 1.00 72.94  ? 153 LEU S CA  1 
ATOM 7994 C C   . LEU E 5 165 ? 117.314 156.817 155.815 1.00 73.41  ? 153 LEU S C   1 
ATOM 7995 O O   . LEU E 5 165 ? 118.020 155.912 155.357 1.00 71.69  ? 153 LEU S O   1 
ATOM 7996 C CB  . LEU E 5 165 ? 119.009 158.277 156.921 1.00 74.90  ? 153 LEU S CB  1 
ATOM 7997 C CG  . LEU E 5 165 ? 119.775 159.598 157.004 1.00 71.56  ? 153 LEU S CG  1 
ATOM 7998 C CD1 . LEU E 5 165 ? 120.835 159.539 158.088 1.00 67.51  ? 153 LEU S CD1 1 
ATOM 7999 C CD2 . LEU E 5 165 ? 120.397 159.937 155.660 1.00 69.14  ? 153 LEU S CD2 1 
ATOM 8000 N N   . LEU E 5 166 ? 116.073 156.606 156.245 1.00 76.30  ? 154 LEU S N   1 
ATOM 8001 C CA  . LEU E 5 166 ? 115.451 155.285 156.206 1.00 72.68  ? 154 LEU S CA  1 
ATOM 8002 C C   . LEU E 5 166 ? 115.214 154.902 154.751 1.00 69.07  ? 154 LEU S C   1 
ATOM 8003 O O   . LEU E 5 166 ? 114.305 155.417 154.098 1.00 71.10  ? 154 LEU S O   1 
ATOM 8004 C CB  . LEU E 5 166 ? 114.154 155.291 157.008 1.00 71.65  ? 154 LEU S CB  1 
ATOM 8005 C CG  . LEU E 5 166 ? 113.442 153.966 157.292 1.00 70.55  ? 154 LEU S CG  1 
ATOM 8006 C CD1 . LEU E 5 166 ? 112.680 154.063 158.602 1.00 69.92  ? 154 LEU S CD1 1 
ATOM 8007 C CD2 . LEU E 5 166 ? 112.493 153.589 156.167 1.00 72.63  ? 154 LEU S CD2 1 
ATOM 8008 N N   . HIS E 5 167 ? 116.037 153.991 154.240 1.00 69.60  ? 155 HIS S N   1 
ATOM 8009 C CA  . HIS E 5 167 ? 115.939 153.575 152.851 1.00 72.48  ? 155 HIS S CA  1 
ATOM 8010 C C   . HIS E 5 167 ? 114.729 152.663 152.649 1.00 78.21  ? 155 HIS S C   1 
ATOM 8011 O O   . HIS E 5 167 ? 114.046 152.264 153.597 1.00 78.08  ? 155 HIS S O   1 
ATOM 8012 C CB  . HIS E 5 167 ? 117.223 152.869 152.418 1.00 74.44  ? 155 HIS S CB  1 
ATOM 8013 C CG  . HIS E 5 167 ? 117.483 152.932 150.946 1.00 74.67  ? 155 HIS S CG  1 
ATOM 8014 N ND1 . HIS E 5 167 ? 117.140 151.912 150.085 1.00 75.31  ? 155 HIS S ND1 1 
ATOM 8015 C CD2 . HIS E 5 167 ? 118.053 153.893 150.182 1.00 72.60  ? 155 HIS S CD2 1 
ATOM 8016 C CE1 . HIS E 5 167 ? 117.488 152.242 148.854 1.00 74.39  ? 155 HIS S CE1 1 
ATOM 8017 N NE2 . HIS E 5 167 ? 118.044 153.439 148.885 1.00 74.12  ? 155 HIS S NE2 1 
ATOM 8018 N N   . SER E 5 168 ? 114.466 152.336 151.382 1.00 79.90  ? 156 SER S N   1 
ATOM 8019 C CA  . SER E 5 168 ? 113.330 151.485 151.049 1.00 81.45  ? 156 SER S CA  1 
ATOM 8020 C C   . SER E 5 168 ? 113.509 150.053 151.536 1.00 78.78  ? 156 SER S C   1 
ATOM 8021 O O   . SER E 5 168 ? 112.514 149.336 151.686 1.00 78.49  ? 156 SER S O   1 
ATOM 8022 C CB  . SER E 5 168 ? 113.095 151.491 149.538 1.00 79.33  ? 156 SER S CB  1 
ATOM 8023 O OG  . SER E 5 168 ? 114.316 151.360 148.832 1.00 73.00  ? 156 SER S OG  1 
ATOM 8024 N N   . ASN E 5 169 ? 114.742 149.622 151.787 1.00 72.78  ? 157 ASN S N   1 
ATOM 8025 C CA  . ASN E 5 169 ? 115.013 148.262 152.232 1.00 74.01  ? 157 ASN S CA  1 
ATOM 8026 C C   . ASN E 5 169 ? 114.926 148.101 153.744 1.00 74.79  ? 157 ASN S C   1 
ATOM 8027 O O   . ASN E 5 169 ? 115.162 146.999 154.249 1.00 78.07  ? 157 ASN S O   1 
ATOM 8028 C CB  . ASN E 5 169 ? 116.393 147.811 151.741 1.00 76.79  ? 157 ASN S CB  1 
ATOM 8029 C CG  . ASN E 5 169 ? 117.482 148.822 152.041 1.00 74.98  ? 157 ASN S CG  1 
ATOM 8030 O OD1 . ASN E 5 169 ? 117.564 149.357 153.146 1.00 74.21  ? 157 ASN S OD1 1 
ATOM 8031 N ND2 . ASN E 5 169 ? 118.329 149.085 151.054 1.00 76.54  ? 157 ASN S ND2 1 
ATOM 8032 N N   . GLY E 5 170 ? 114.595 149.165 154.474 1.00 71.22  ? 158 GLY S N   1 
ATOM 8033 C CA  . GLY E 5 170 ? 114.455 149.099 155.911 1.00 73.73  ? 158 GLY S CA  1 
ATOM 8034 C C   . GLY E 5 170 ? 115.715 149.381 156.698 1.00 78.21  ? 158 GLY S C   1 
ATOM 8035 O O   . GLY E 5 170 ? 115.650 149.453 157.931 1.00 79.78  ? 158 GLY S O   1 
ATOM 8036 N N   . ASN E 5 171 ? 116.855 149.542 156.034 1.00 69.86  ? 159 ASN S N   1 
ATOM 8037 C CA  . ASN E 5 171 ? 118.114 149.841 156.701 1.00 63.04  ? 159 ASN S CA  1 
ATOM 8038 C C   . ASN E 5 171 ? 118.345 151.345 156.700 1.00 62.32  ? 159 ASN S C   1 
ATOM 8039 O O   . ASN E 5 171 ? 118.298 151.985 155.644 1.00 64.35  ? 159 ASN S O   1 
ATOM 8040 C CB  . ASN E 5 171 ? 119.281 149.126 156.018 1.00 64.60  ? 159 ASN S CB  1 
ATOM 8041 C CG  . ASN E 5 171 ? 119.310 147.641 156.318 1.00 66.22  ? 159 ASN S CG  1 
ATOM 8042 O OD1 . ASN E 5 171 ? 119.326 146.811 155.409 1.00 66.92  ? 159 ASN S OD1 1 
ATOM 8043 N ND2 . ASN E 5 171 ? 119.315 147.297 157.600 1.00 64.42  ? 159 ASN S ND2 1 
ATOM 8044 N N   . THR E 5 172 ? 118.595 151.902 157.881 1.00 57.54  ? 160 THR S N   1 
ATOM 8045 C CA  . THR E 5 172 ? 118.891 153.319 158.037 1.00 59.64  ? 160 THR S CA  1 
ATOM 8046 C C   . THR E 5 172 ? 120.394 153.496 158.195 1.00 67.89  ? 160 THR S C   1 
ATOM 8047 O O   . THR E 5 172 ? 121.005 152.888 159.080 1.00 70.47  ? 160 THR S O   1 
ATOM 8048 C CB  . THR E 5 172 ? 118.161 153.902 159.247 1.00 52.76  ? 160 THR S CB  1 
ATOM 8049 O OG1 . THR E 5 172 ? 116.814 153.414 159.275 1.00 62.66  ? 160 THR S OG1 1 
ATOM 8050 C CG2 . THR E 5 172 ? 118.139 155.419 159.174 1.00 55.39  ? 160 THR S CG2 1 
ATOM 8051 N N   . TYR E 5 173 ? 120.985 154.328 157.341 1.00 56.60  ? 161 TYR S N   1 
ATOM 8052 C CA  . TYR E 5 173 ? 122.437 154.490 157.297 1.00 48.90  ? 161 TYR S CA  1 
ATOM 8053 C C   . TYR E 5 173 ? 122.832 155.672 158.173 1.00 48.05  ? 161 TYR S C   1 
ATOM 8054 O O   . TYR E 5 173 ? 122.973 156.802 157.708 1.00 61.59  ? 161 TYR S O   1 
ATOM 8055 C CB  . TYR E 5 173 ? 122.911 154.661 155.861 1.00 47.09  ? 161 TYR S CB  1 
ATOM 8056 C CG  . TYR E 5 173 ? 122.533 153.504 154.965 1.00 54.64  ? 161 TYR S CG  1 
ATOM 8057 C CD1 . TYR E 5 173 ? 123.311 152.357 154.918 1.00 62.57  ? 161 TYR S CD1 1 
ATOM 8058 C CD2 . TYR E 5 173 ? 121.395 153.555 154.174 1.00 53.69  ? 161 TYR S CD2 1 
ATOM 8059 C CE1 . TYR E 5 173 ? 122.971 151.295 154.106 1.00 59.80  ? 161 TYR S CE1 1 
ATOM 8060 C CE2 . TYR E 5 173 ? 121.047 152.497 153.358 1.00 57.07  ? 161 TYR S CE2 1 
ATOM 8061 C CZ  . TYR E 5 173 ? 121.838 151.370 153.328 1.00 60.06  ? 161 TYR S CZ  1 
ATOM 8062 O OH  . TYR E 5 173 ? 121.497 150.313 152.518 1.00 64.47  ? 161 TYR S OH  1 
ATOM 8063 N N   . LEU E 5 174 ? 123.014 155.400 159.462 1.00 36.41  ? 162 LEU S N   1 
ATOM 8064 C CA  . LEU E 5 174 ? 123.502 156.379 160.422 1.00 40.01  ? 162 LEU S CA  1 
ATOM 8065 C C   . LEU E 5 174 ? 124.611 155.746 161.244 1.00 44.27  ? 162 LEU S C   1 
ATOM 8066 O O   . LEU E 5 174 ? 124.456 154.626 161.739 1.00 50.44  ? 162 LEU S O   1 
ATOM 8067 C CB  . LEU E 5 174 ? 122.390 156.862 161.350 1.00 44.50  ? 162 LEU S CB  1 
ATOM 8068 C CG  . LEU E 5 174 ? 122.864 157.931 162.333 1.00 44.42  ? 162 LEU S CG  1 
ATOM 8069 C CD1 . LEU E 5 174 ? 123.032 159.270 161.639 1.00 51.04  ? 162 LEU S CD1 1 
ATOM 8070 C CD2 . LEU E 5 174 ? 121.935 158.034 163.515 1.00 53.54  ? 162 LEU S CD2 1 
ATOM 8071 N N   . TYR E 5 175 ? 125.718 156.463 161.401 1.00 42.40  ? 163 TYR S N   1 
ATOM 8072 C CA  . TYR E 5 175 ? 126.892 155.949 162.090 1.00 38.65  ? 163 TYR S CA  1 
ATOM 8073 C C   . TYR E 5 175 ? 127.275 156.891 163.220 1.00 42.32  ? 163 TYR S C   1 
ATOM 8074 O O   . TYR E 5 175 ? 127.278 158.113 163.046 1.00 47.89  ? 163 TYR S O   1 
ATOM 8075 C CB  . TYR E 5 175 ? 128.066 155.778 161.117 1.00 38.52  ? 163 TYR S CB  1 
ATOM 8076 C CG  . TYR E 5 175 ? 127.834 154.716 160.066 1.00 32.99  ? 163 TYR S CG  1 
ATOM 8077 C CD1 . TYR E 5 175 ? 126.901 154.902 159.059 1.00 39.68  ? 163 TYR S CD1 1 
ATOM 8078 C CD2 . TYR E 5 175 ? 128.543 153.526 160.085 1.00 34.49  ? 163 TYR S CD2 1 
ATOM 8079 C CE1 . TYR E 5 175 ? 126.679 153.938 158.107 1.00 43.19  ? 163 TYR S CE1 1 
ATOM 8080 C CE2 . TYR E 5 175 ? 128.327 152.556 159.131 1.00 31.97  ? 163 TYR S CE2 1 
ATOM 8081 C CZ  . TYR E 5 175 ? 127.393 152.769 158.144 1.00 36.79  ? 163 TYR S CZ  1 
ATOM 8082 O OH  . TYR E 5 175 ? 127.164 151.813 157.187 1.00 44.46  ? 163 TYR S OH  1 
ATOM 8083 N N   . TRP E 5 176 ? 127.595 156.320 164.378 1.00 45.88  ? 164 TRP S N   1 
ATOM 8084 C CA  . TRP E 5 176 ? 127.984 157.084 165.557 1.00 47.05  ? 164 TRP S CA  1 
ATOM 8085 C C   . TRP E 5 176 ? 129.442 156.779 165.875 1.00 45.29  ? 164 TRP S C   1 
ATOM 8086 O O   . TRP E 5 176 ? 129.807 155.615 166.067 1.00 56.78  ? 164 TRP S O   1 
ATOM 8087 C CB  . TRP E 5 176 ? 127.091 156.745 166.751 1.00 58.11  ? 164 TRP S CB  1 
ATOM 8088 C CG  . TRP E 5 176 ? 125.752 157.422 166.723 1.00 56.92  ? 164 TRP S CG  1 
ATOM 8089 C CD1 . TRP E 5 176 ? 124.570 156.879 166.315 1.00 54.87  ? 164 TRP S CD1 1 
ATOM 8090 C CD2 . TRP E 5 176 ? 125.457 158.765 167.127 1.00 50.80  ? 164 TRP S CD2 1 
ATOM 8091 N NE1 . TRP E 5 176 ? 123.559 157.799 166.435 1.00 54.38  ? 164 TRP S NE1 1 
ATOM 8092 C CE2 . TRP E 5 176 ? 124.078 158.965 166.932 1.00 49.66  ? 164 TRP S CE2 1 
ATOM 8093 C CE3 . TRP E 5 176 ? 126.225 159.816 167.634 1.00 55.66  ? 164 TRP S CE3 1 
ATOM 8094 C CZ2 . TRP E 5 176 ? 123.451 160.172 167.223 1.00 55.54  ? 164 TRP S CZ2 1 
ATOM 8095 C CZ3 . TRP E 5 176 ? 125.601 161.014 167.923 1.00 57.57  ? 164 TRP S CZ3 1 
ATOM 8096 C CH2 . TRP E 5 176 ? 124.228 161.182 167.717 1.00 58.51  ? 164 TRP S CH2 1 
ATOM 8097 N N   . PHE E 5 177 ? 130.265 157.823 165.937 1.00 45.04  ? 165 PHE S N   1 
ATOM 8098 C CA  . PHE E 5 177 ? 131.692 157.691 166.184 1.00 52.37  ? 165 PHE S CA  1 
ATOM 8099 C C   . PHE E 5 177 ? 132.059 158.347 167.507 1.00 59.00  ? 165 PHE S C   1 
ATOM 8100 O O   . PHE E 5 177 ? 131.408 159.297 167.951 1.00 66.75  ? 165 PHE S O   1 
ATOM 8101 C CB  . PHE E 5 177 ? 132.515 158.317 165.055 1.00 53.60  ? 165 PHE S CB  1 
ATOM 8102 C CG  . PHE E 5 177 ? 132.258 157.710 163.711 1.00 49.68  ? 165 PHE S CG  1 
ATOM 8103 C CD1 . PHE E 5 177 ? 132.923 156.565 163.318 1.00 45.45  ? 165 PHE S CD1 1 
ATOM 8104 C CD2 . PHE E 5 177 ? 131.352 158.283 162.841 1.00 55.51  ? 165 PHE S CD2 1 
ATOM 8105 C CE1 . PHE E 5 177 ? 132.690 156.004 162.085 1.00 42.18  ? 165 PHE S CE1 1 
ATOM 8106 C CE2 . PHE E 5 177 ? 131.115 157.725 161.604 1.00 54.20  ? 165 PHE S CE2 1 
ATOM 8107 C CZ  . PHE E 5 177 ? 131.784 156.584 161.226 1.00 46.74  ? 165 PHE S CZ  1 
ATOM 8108 N N   . LEU E 5 178 ? 133.113 157.828 168.132 1.00 60.03  ? 166 LEU S N   1 
ATOM 8109 C CA  . LEU E 5 178 ? 133.621 158.335 169.399 1.00 57.59  ? 166 LEU S CA  1 
ATOM 8110 C C   . LEU E 5 178 ? 135.093 158.685 169.255 1.00 62.03  ? 166 LEU S C   1 
ATOM 8111 O O   . LEU E 5 178 ? 135.883 157.868 168.774 1.00 67.66  ? 166 LEU S O   1 
ATOM 8112 C CB  . LEU E 5 178 ? 133.440 157.309 170.517 1.00 61.74  ? 166 LEU S CB  1 
ATOM 8113 C CG  . LEU E 5 178 ? 134.153 157.648 171.826 1.00 67.05  ? 166 LEU S CG  1 
ATOM 8114 C CD1 . LEU E 5 178 ? 133.227 158.350 172.791 1.00 65.82  ? 166 LEU S CD1 1 
ATOM 8115 C CD2 . LEU E 5 178 ? 134.716 156.388 172.451 1.00 65.88  ? 166 LEU S CD2 1 
ATOM 8116 N N   . GLN E 5 179 ? 135.460 159.888 169.686 1.00 66.97  ? 167 GLN S N   1 
ATOM 8117 C CA  . GLN E 5 179 ? 136.840 160.356 169.627 1.00 72.54  ? 167 GLN S CA  1 
ATOM 8118 C C   . GLN E 5 179 ? 137.274 160.779 171.024 1.00 74.42  ? 167 GLN S C   1 
ATOM 8119 O O   . GLN E 5 179 ? 136.887 161.851 171.501 1.00 73.23  ? 167 GLN S O   1 
ATOM 8120 C CB  . GLN E 5 179 ? 136.988 161.508 168.635 1.00 71.84  ? 167 GLN S CB  1 
ATOM 8121 C CG  . GLN E 5 179 ? 138.415 162.007 168.493 1.00 72.52  ? 167 GLN S CG  1 
ATOM 8122 C CD  . GLN E 5 179 ? 138.577 163.020 167.380 1.00 70.86  ? 167 GLN S CD  1 
ATOM 8123 O OE1 . GLN E 5 179 ? 137.645 163.752 167.050 1.00 70.15  ? 167 GLN S OE1 1 
ATOM 8124 N NE2 . GLN E 5 179 ? 139.764 163.063 166.789 1.00 74.40  ? 167 GLN S NE2 1 
ATOM 8125 N N   . ARG E 5 180 ? 138.074 159.938 171.679 1.00 91.29  ? 168 ARG S N   1 
ATOM 8126 C CA  . ARG E 5 180 ? 138.677 160.318 172.943 1.00 88.00  ? 168 ARG S CA  1 
ATOM 8127 C C   . ARG E 5 180 ? 139.732 161.397 172.711 1.00 88.04  ? 168 ARG S C   1 
ATOM 8128 O O   . ARG E 5 180 ? 140.282 161.513 171.613 1.00 89.92  ? 168 ARG S O   1 
ATOM 8129 C CB  . ARG E 5 180 ? 139.308 159.109 173.631 1.00 87.87  ? 168 ARG S CB  1 
ATOM 8130 C CG  . ARG E 5 180 ? 138.337 158.032 174.094 1.00 88.93  ? 168 ARG S CG  1 
ATOM 8131 C CD  . ARG E 5 180 ? 138.921 156.644 173.862 1.00 91.24  ? 168 ARG S CD  1 
ATOM 8132 N NE  . ARG E 5 180 ? 137.906 155.631 173.598 1.00 90.56  ? 168 ARG S NE  1 
ATOM 8133 C CZ  . ARG E 5 180 ? 137.176 155.046 174.537 1.00 90.27  ? 168 ARG S CZ  1 
ATOM 8134 N NH1 . ARG E 5 180 ? 137.295 155.378 175.812 1.00 91.61  ? 168 ARG S NH1 1 
ATOM 8135 N NH2 . ARG E 5 180 ? 136.307 154.101 174.190 1.00 89.50  ? 168 ARG S NH2 1 
ATOM 8136 N N   . PRO E 5 181 ? 140.022 162.209 173.727 1.00 104.89 ? 169 PRO S N   1 
ATOM 8137 C CA  . PRO E 5 181 ? 141.022 163.272 173.556 1.00 107.04 ? 169 PRO S CA  1 
ATOM 8138 C C   . PRO E 5 181 ? 142.389 162.703 173.203 1.00 107.54 ? 169 PRO S C   1 
ATOM 8139 O O   . PRO E 5 181 ? 142.912 161.821 173.889 1.00 105.44 ? 169 PRO S O   1 
ATOM 8140 C CB  . PRO E 5 181 ? 141.035 163.969 174.921 1.00 107.87 ? 169 PRO S CB  1 
ATOM 8141 C CG  . PRO E 5 181 ? 139.712 163.645 175.525 1.00 106.82 ? 169 PRO S CG  1 
ATOM 8142 C CD  . PRO E 5 181 ? 139.388 162.262 175.055 1.00 107.50 ? 169 PRO S CD  1 
ATOM 8143 N N   . GLY E 5 182 ? 142.967 163.219 172.120 1.00 111.63 ? 170 GLY S N   1 
ATOM 8144 C CA  . GLY E 5 182 ? 144.283 162.809 171.682 1.00 110.98 ? 170 GLY S CA  1 
ATOM 8145 C C   . GLY E 5 182 ? 144.339 161.498 170.930 1.00 111.14 ? 170 GLY S C   1 
ATOM 8146 O O   . GLY E 5 182 ? 145.441 161.048 170.591 1.00 112.86 ? 170 GLY S O   1 
ATOM 8147 N N   . GLN E 5 183 ? 143.201 160.873 170.654 1.00 95.31  ? 171 GLN S N   1 
ATOM 8148 C CA  . GLN E 5 183 ? 143.148 159.581 169.986 1.00 95.38  ? 171 GLN S CA  1 
ATOM 8149 C C   . GLN E 5 183 ? 142.408 159.717 168.656 1.00 93.42  ? 171 GLN S C   1 
ATOM 8150 O O   . GLN E 5 183 ? 142.060 160.819 168.222 1.00 88.87  ? 171 GLN S O   1 
ATOM 8151 C CB  . GLN E 5 183 ? 142.488 158.536 170.889 1.00 92.27  ? 171 GLN S CB  1 
ATOM 8152 C CG  . GLN E 5 183 ? 143.167 158.358 172.235 1.00 92.82  ? 171 GLN S CG  1 
ATOM 8153 C CD  . GLN E 5 183 ? 142.708 157.107 172.956 1.00 96.24  ? 171 GLN S CD  1 
ATOM 8154 O OE1 . GLN E 5 183 ? 142.013 156.267 172.385 1.00 94.74  ? 171 GLN S OE1 1 
ATOM 8155 N NE2 . GLN E 5 183 ? 143.096 156.976 174.219 1.00 96.96  ? 171 GLN S NE2 1 
ATOM 8156 N N   . SER E 5 184 ? 142.172 158.575 168.007 1.00 76.13  ? 172 SER S N   1 
ATOM 8157 C CA  . SER E 5 184 ? 141.468 158.504 166.739 1.00 68.81  ? 172 SER S CA  1 
ATOM 8158 C C   . SER E 5 184 ? 140.035 158.029 166.948 1.00 72.02  ? 172 SER S C   1 
ATOM 8159 O O   . SER E 5 184 ? 139.754 157.279 167.888 1.00 71.89  ? 172 SER S O   1 
ATOM 8160 C CB  . SER E 5 184 ? 142.185 157.552 165.778 1.00 66.68  ? 172 SER S CB  1 
ATOM 8161 O OG  . SER E 5 184 ? 143.590 157.691 165.883 1.00 72.86  ? 172 SER S OG  1 
ATOM 8162 N N   . PRO E 5 185 ? 139.110 158.460 166.090 1.00 63.80  ? 173 PRO S N   1 
ATOM 8163 C CA  . PRO E 5 185 ? 137.708 158.061 166.257 1.00 63.95  ? 173 PRO S CA  1 
ATOM 8164 C C   . PRO E 5 185 ? 137.520 156.554 166.151 1.00 61.44  ? 173 PRO S C   1 
ATOM 8165 O O   . PRO E 5 185 ? 138.218 155.866 165.404 1.00 63.10  ? 173 PRO S O   1 
ATOM 8166 C CB  . PRO E 5 185 ? 136.995 158.794 165.115 1.00 59.35  ? 173 PRO S CB  1 
ATOM 8167 C CG  . PRO E 5 185 ? 137.874 159.956 164.812 1.00 54.38  ? 173 PRO S CG  1 
ATOM 8168 C CD  . PRO E 5 185 ? 139.273 159.462 165.024 1.00 60.89  ? 173 PRO S CD  1 
ATOM 8169 N N   . GLN E 5 186 ? 136.562 156.045 166.925 1.00 57.26  ? 174 GLN S N   1 
ATOM 8170 C CA  . GLN E 5 186 ? 136.196 154.637 166.914 1.00 56.00  ? 174 GLN S CA  1 
ATOM 8171 C C   . GLN E 5 186 ? 134.696 154.505 166.703 1.00 59.69  ? 174 GLN S C   1 
ATOM 8172 O O   . GLN E 5 186 ? 133.913 155.295 167.238 1.00 64.34  ? 174 GLN S O   1 
ATOM 8173 C CB  . GLN E 5 186 ? 136.600 153.936 168.216 1.00 60.31  ? 174 GLN S CB  1 
ATOM 8174 C CG  . GLN E 5 186 ? 137.801 154.548 168.913 1.00 65.54  ? 174 GLN S CG  1 
ATOM 8175 C CD  . GLN E 5 186 ? 138.170 153.808 170.182 1.00 69.07  ? 174 GLN S CD  1 
ATOM 8176 O OE1 . GLN E 5 186 ? 137.790 152.654 170.375 1.00 65.08  ? 174 GLN S OE1 1 
ATOM 8177 N NE2 . GLN E 5 186 ? 138.923 154.468 171.054 1.00 70.39  ? 174 GLN S NE2 1 
ATOM 8178 N N   . LEU E 5 187 ? 134.302 153.504 165.922 1.00 52.42  ? 175 LEU S N   1 
ATOM 8179 C CA  . LEU E 5 187 ? 132.897 153.282 165.613 1.00 43.21  ? 175 LEU S CA  1 
ATOM 8180 C C   . LEU E 5 187 ? 132.190 152.606 166.780 1.00 49.76  ? 175 LEU S C   1 
ATOM 8181 O O   . LEU E 5 187 ? 132.740 151.707 167.421 1.00 59.80  ? 175 LEU S O   1 
ATOM 8182 C CB  . LEU E 5 187 ? 132.762 152.429 164.353 1.00 37.50  ? 175 LEU S CB  1 
ATOM 8183 C CG  . LEU E 5 187 ? 131.352 152.027 163.926 1.00 37.93  ? 175 LEU S CG  1 
ATOM 8184 C CD1 . LEU E 5 187 ? 130.709 153.131 163.110 1.00 48.41  ? 175 LEU S CD1 1 
ATOM 8185 C CD2 . LEU E 5 187 ? 131.381 150.732 163.143 1.00 44.82  ? 175 LEU S CD2 1 
ATOM 8186 N N   . LEU E 5 188 ? 130.961 153.046 167.054 1.00 57.64  ? 176 LEU S N   1 
ATOM 8187 C CA  . LEU E 5 188 ? 130.142 152.483 168.120 1.00 50.14  ? 176 LEU S CA  1 
ATOM 8188 C C   . LEU E 5 188 ? 128.909 151.772 167.578 1.00 55.59  ? 176 LEU S C   1 
ATOM 8189 O O   . LEU E 5 188 ? 128.688 150.595 167.875 1.00 55.29  ? 176 LEU S O   1 
ATOM 8190 C CB  . LEU E 5 188 ? 129.726 153.589 169.099 1.00 45.49  ? 176 LEU S CB  1 
ATOM 8191 C CG  . LEU E 5 188 ? 130.848 154.383 169.768 1.00 51.27  ? 176 LEU S CG  1 
ATOM 8192 C CD1 . LEU E 5 188 ? 130.265 155.444 170.683 1.00 56.70  ? 176 LEU S CD1 1 
ATOM 8193 C CD2 . LEU E 5 188 ? 131.776 153.461 170.536 1.00 51.54  ? 176 LEU S CD2 1 
ATOM 8194 N N   . ILE E 5 189 ? 128.091 152.467 166.791 1.00 55.72  ? 177 ILE S N   1 
ATOM 8195 C CA  . ILE E 5 189 ? 126.885 151.916 166.185 1.00 45.57  ? 177 ILE S CA  1 
ATOM 8196 C C   . ILE E 5 189 ? 126.899 152.265 164.707 1.00 43.48  ? 177 ILE S C   1 
ATOM 8197 O O   . ILE E 5 189 ? 127.216 153.401 164.340 1.00 47.97  ? 177 ILE S O   1 
ATOM 8198 C CB  . ILE E 5 189 ? 125.608 152.465 166.852 1.00 50.34  ? 177 ILE S CB  1 
ATOM 8199 C CG1 . ILE E 5 189 ? 125.724 152.407 168.375 1.00 54.50  ? 177 ILE S CG1 1 
ATOM 8200 C CG2 . ILE E 5 189 ? 124.397 151.720 166.356 1.00 58.96  ? 177 ILE S CG2 1 
ATOM 8201 C CD1 . ILE E 5 189 ? 125.468 153.723 169.044 1.00 57.37  ? 177 ILE S CD1 1 
ATOM 8202 N N   . TYR E 5 190 ? 126.557 151.298 163.850 1.00 42.16  ? 178 TYR S N   1 
ATOM 8203 C CA  . TYR E 5 190 ? 126.717 151.543 162.425 1.00 54.14  ? 178 TYR S CA  1 
ATOM 8204 C C   . TYR E 5 190 ? 125.430 151.697 161.623 1.00 57.35  ? 178 TYR S C   1 
ATOM 8205 O O   . TYR E 5 190 ? 125.487 152.289 160.542 1.00 67.67  ? 178 TYR S O   1 
ATOM 8206 C CB  . TYR E 5 190 ? 127.598 150.465 161.767 1.00 48.06  ? 178 TYR S CB  1 
ATOM 8207 C CG  . TYR E 5 190 ? 127.387 149.022 162.159 1.00 43.65  ? 178 TYR S CG  1 
ATOM 8208 C CD1 . TYR E 5 190 ? 128.052 148.475 163.246 1.00 46.93  ? 178 TYR S CD1 1 
ATOM 8209 C CD2 . TYR E 5 190 ? 126.590 148.185 161.394 1.00 53.53  ? 178 TYR S CD2 1 
ATOM 8210 C CE1 . TYR E 5 190 ? 127.890 147.149 163.589 1.00 45.50  ? 178 TYR S CE1 1 
ATOM 8211 C CE2 . TYR E 5 190 ? 126.425 146.856 161.727 1.00 53.67  ? 178 TYR S CE2 1 
ATOM 8212 C CZ  . TYR E 5 190 ? 127.077 146.343 162.826 1.00 50.62  ? 178 TYR S CZ  1 
ATOM 8213 O OH  . TYR E 5 190 ? 126.912 145.021 163.165 1.00 54.30  ? 178 TYR S OH  1 
ATOM 8214 N N   . ARG E 5 191 ? 124.280 151.184 162.072 1.00 53.88  ? 179 ARG S N   1 
ATOM 8215 C CA  . ARG E 5 191 ? 123.033 151.539 161.394 1.00 48.35  ? 179 ARG S CA  1 
ATOM 8216 C C   . ARG E 5 191 ? 122.018 152.210 162.312 1.00 54.48  ? 179 ARG S C   1 
ATOM 8217 O O   . ARG E 5 191 ? 121.733 153.395 162.124 1.00 59.33  ? 179 ARG S O   1 
ATOM 8218 C CB  . ARG E 5 191 ? 122.452 150.299 160.715 1.00 53.50  ? 179 ARG S CB  1 
ATOM 8219 C CG  . ARG E 5 191 ? 123.056 150.058 159.344 1.00 51.43  ? 179 ARG S CG  1 
ATOM 8220 C CD  . ARG E 5 191 ? 122.529 148.795 158.700 1.00 62.38  ? 179 ARG S CD  1 
ATOM 8221 N NE  . ARG E 5 191 ? 123.296 148.443 157.511 1.00 60.62  ? 179 ARG S NE  1 
ATOM 8222 C CZ  . ARG E 5 191 ? 124.453 147.796 157.529 1.00 55.34  ? 179 ARG S CZ  1 
ATOM 8223 N NH1 . ARG E 5 191 ? 125.007 147.402 158.663 1.00 50.85  ? 179 ARG S NH1 1 
ATOM 8224 N NH2 . ARG E 5 191 ? 125.068 147.534 156.380 1.00 56.57  ? 179 ARG S NH2 1 
ATOM 8225 N N   . MET E 5 192 ? 121.464 151.512 163.298 1.00 63.06  ? 180 MET S N   1 
ATOM 8226 C CA  . MET E 5 192 ? 120.609 152.188 164.273 1.00 63.23  ? 180 MET S CA  1 
ATOM 8227 C C   . MET E 5 192 ? 120.902 151.774 165.707 1.00 65.18  ? 180 MET S C   1 
ATOM 8228 O O   . MET E 5 192 ? 120.874 152.619 166.603 1.00 67.31  ? 180 MET S O   1 
ATOM 8229 C CB  . MET E 5 192 ? 119.116 151.949 163.934 1.00 70.36  ? 180 MET S CB  1 
ATOM 8230 C CG  . MET E 5 192 ? 118.405 150.889 164.771 1.00 72.11  ? 180 MET S CG  1 
ATOM 8231 S SD  . MET E 5 192 ? 116.621 150.860 164.518 1.00 75.61  ? 180 MET S SD  1 
ATOM 8232 C CE  . MET E 5 192 ? 116.212 152.581 164.796 1.00 66.04  ? 180 MET S CE  1 
ATOM 8233 N N   . SER E 5 193 ? 121.180 150.492 165.940 1.00 58.46  ? 181 SER S N   1 
ATOM 8234 C CA  . SER E 5 193 ? 121.521 149.981 167.257 1.00 62.03  ? 181 SER S CA  1 
ATOM 8235 C C   . SER E 5 193 ? 122.543 148.861 167.171 1.00 68.30  ? 181 SER S C   1 
ATOM 8236 O O   . SER E 5 193 ? 122.873 148.266 168.202 1.00 72.87  ? 181 SER S O   1 
ATOM 8237 C CB  . SER E 5 193 ? 120.267 149.483 167.994 1.00 60.28  ? 181 SER S CB  1 
ATOM 8238 O OG  . SER E 5 193 ? 119.580 148.507 167.231 1.00 63.25  ? 181 SER S OG  1 
ATOM 8239 N N   . ASN E 5 194 ? 123.051 148.562 165.980 1.00 56.59  ? 182 ASN S N   1 
ATOM 8240 C CA  . ASN E 5 194 ? 123.971 147.454 165.766 1.00 51.17  ? 182 ASN S CA  1 
ATOM 8241 C C   . ASN E 5 194 ? 125.293 147.790 166.437 1.00 57.63  ? 182 ASN S C   1 
ATOM 8242 O O   . ASN E 5 194 ? 126.065 148.614 165.946 1.00 62.89  ? 182 ASN S O   1 
ATOM 8243 C CB  . ASN E 5 194 ? 124.146 147.207 164.274 1.00 50.87  ? 182 ASN S CB  1 
ATOM 8244 C CG  . ASN E 5 194 ? 122.883 146.691 163.620 1.00 54.90  ? 182 ASN S CG  1 
ATOM 8245 O OD1 . ASN E 5 194 ? 122.448 147.206 162.591 1.00 57.84  ? 182 ASN S OD1 1 
ATOM 8246 N ND2 . ASN E 5 194 ? 122.287 145.664 164.212 1.00 60.67  ? 182 ASN S ND2 1 
ATOM 8247 N N   . LEU E 5 195 ? 125.545 147.158 167.578 1.00 61.31  ? 183 LEU S N   1 
ATOM 8248 C CA  . LEU E 5 195 ? 126.747 147.437 168.345 1.00 56.50  ? 183 LEU S CA  1 
ATOM 8249 C C   . LEU E 5 195 ? 127.988 147.012 167.572 1.00 58.69  ? 183 LEU S C   1 
ATOM 8250 O O   . LEU E 5 195 ? 128.011 145.959 166.931 1.00 57.09  ? 183 LEU S O   1 
ATOM 8251 C CB  . LEU E 5 195 ? 126.688 146.712 169.687 1.00 62.71  ? 183 LEU S CB  1 
ATOM 8252 C CG  . LEU E 5 195 ? 127.399 147.389 170.854 1.00 63.34  ? 183 LEU S CG  1 
ATOM 8253 C CD1 . LEU E 5 195 ? 126.689 148.676 171.233 1.00 66.54  ? 183 LEU S CD1 1 
ATOM 8254 C CD2 . LEU E 5 195 ? 127.484 146.446 172.041 1.00 61.52  ? 183 LEU S CD2 1 
ATOM 8255 N N   . ALA E 5 196 ? 129.026 147.842 167.636 1.00 65.68  ? 184 ALA S N   1 
ATOM 8256 C CA  . ALA E 5 196 ? 130.284 147.518 166.986 1.00 66.08  ? 184 ALA S CA  1 
ATOM 8257 C C   . ALA E 5 196 ? 130.976 146.377 167.729 1.00 68.83  ? 184 ALA S C   1 
ATOM 8258 O O   . ALA E 5 196 ? 130.501 145.880 168.754 1.00 72.39  ? 184 ALA S O   1 
ATOM 8259 C CB  . ALA E 5 196 ? 131.178 148.752 166.915 1.00 65.85  ? 184 ALA S CB  1 
ATOM 8260 N N   . SER E 5 197 ? 132.123 145.959 167.205 1.00 82.60  ? 185 SER S N   1 
ATOM 8261 C CA  . SER E 5 197 ? 132.865 144.840 167.769 1.00 86.62  ? 185 SER S CA  1 
ATOM 8262 C C   . SER E 5 197 ? 133.800 145.344 168.861 1.00 88.90  ? 185 SER S C   1 
ATOM 8263 O O   . SER E 5 197 ? 134.728 146.112 168.585 1.00 93.13  ? 185 SER S O   1 
ATOM 8264 C CB  . SER E 5 197 ? 133.651 144.114 166.678 1.00 86.70  ? 185 SER S CB  1 
ATOM 8265 O OG  . SER E 5 197 ? 134.527 143.152 167.237 1.00 87.88  ? 185 SER S OG  1 
ATOM 8266 N N   . GLY E 5 198 ? 133.556 144.911 170.097 1.00 92.88  ? 186 GLY S N   1 
ATOM 8267 C CA  . GLY E 5 198 ? 134.435 145.196 171.210 1.00 93.96  ? 186 GLY S CA  1 
ATOM 8268 C C   . GLY E 5 198 ? 134.029 146.364 172.084 1.00 94.86  ? 186 GLY S C   1 
ATOM 8269 O O   . GLY E 5 198 ? 134.587 146.515 173.179 1.00 93.63  ? 186 GLY S O   1 
ATOM 8270 N N   . VAL E 5 199 ? 133.085 147.192 171.648 1.00 93.10  ? 187 VAL S N   1 
ATOM 8271 C CA  . VAL E 5 199 ? 132.646 148.330 172.453 1.00 95.39  ? 187 VAL S CA  1 
ATOM 8272 C C   . VAL E 5 199 ? 131.736 147.818 173.564 1.00 94.88  ? 187 VAL S C   1 
ATOM 8273 O O   . VAL E 5 199 ? 131.098 146.767 173.403 1.00 94.30  ? 187 VAL S O   1 
ATOM 8274 C CB  . VAL E 5 199 ? 131.949 149.393 171.588 1.00 90.91  ? 187 VAL S CB  1 
ATOM 8275 C CG1 . VAL E 5 199 ? 132.848 149.807 170.434 1.00 90.52  ? 187 VAL S CG1 1 
ATOM 8276 C CG2 . VAL E 5 199 ? 130.622 148.879 171.073 1.00 86.22  ? 187 VAL S CG2 1 
ATOM 8277 N N   . PRO E 5 200 ? 131.658 148.504 174.706 1.00 95.91  ? 188 PRO S N   1 
ATOM 8278 C CA  . PRO E 5 200 ? 130.809 148.016 175.799 1.00 92.71  ? 188 PRO S CA  1 
ATOM 8279 C C   . PRO E 5 200 ? 129.338 148.011 175.412 1.00 93.02  ? 188 PRO S C   1 
ATOM 8280 O O   . PRO E 5 200 ? 128.883 148.810 174.591 1.00 90.73  ? 188 PRO S O   1 
ATOM 8281 C CB  . PRO E 5 200 ? 131.083 149.005 176.940 1.00 95.16  ? 188 PRO S CB  1 
ATOM 8282 C CG  . PRO E 5 200 ? 131.729 150.186 176.304 1.00 94.81  ? 188 PRO S CG  1 
ATOM 8283 C CD  . PRO E 5 200 ? 132.439 149.691 175.090 1.00 94.99  ? 188 PRO S CD  1 
ATOM 8284 N N   . ASP E 5 201 ? 128.593 147.088 176.021 1.00 100.21 ? 189 ASP S N   1 
ATOM 8285 C CA  . ASP E 5 201 ? 127.180 146.908 175.715 1.00 100.24 ? 189 ASP S CA  1 
ATOM 8286 C C   . ASP E 5 201 ? 126.293 147.994 176.309 1.00 98.14  ? 189 ASP S C   1 
ATOM 8287 O O   . ASP E 5 201 ? 125.092 148.012 176.018 1.00 96.89  ? 189 ASP S O   1 
ATOM 8288 C CB  . ASP E 5 201 ? 126.708 145.538 176.208 1.00 99.55  ? 189 ASP S CB  1 
ATOM 8289 N N   . ARG E 5 202 ? 126.843 148.888 177.135 1.00 96.74  ? 190 ARG S N   1 
ATOM 8290 C CA  . ARG E 5 202 ? 126.029 149.945 177.725 1.00 96.38  ? 190 ARG S CA  1 
ATOM 8291 C C   . ARG E 5 202 ? 125.489 150.900 176.667 1.00 97.64  ? 190 ARG S C   1 
ATOM 8292 O O   . ARG E 5 202 ? 124.466 151.556 176.890 1.00 96.19  ? 190 ARG S O   1 
ATOM 8293 C CB  . ARG E 5 202 ? 126.836 150.713 178.771 1.00 95.04  ? 190 ARG S CB  1 
ATOM 8294 C CG  . ARG E 5 202 ? 128.138 151.298 178.255 1.00 95.52  ? 190 ARG S CG  1 
ATOM 8295 C CD  . ARG E 5 202 ? 128.700 152.322 179.226 1.00 97.72  ? 190 ARG S CD  1 
ATOM 8296 N NE  . ARG E 5 202 ? 130.083 152.667 178.920 1.00 98.63  ? 190 ARG S NE  1 
ATOM 8297 C CZ  . ARG E 5 202 ? 131.136 151.990 179.356 1.00 97.33  ? 190 ARG S CZ  1 
ATOM 8298 N NH1 . ARG E 5 202 ? 131.002 150.921 180.123 1.00 97.39  ? 190 ARG S NH1 1 
ATOM 8299 N NH2 . ARG E 5 202 ? 132.355 152.396 179.013 1.00 95.22  ? 190 ARG S NH2 1 
ATOM 8300 N N   . PHE E 5 203 ? 126.158 150.995 175.521 1.00 93.03  ? 191 PHE S N   1 
ATOM 8301 C CA  . PHE E 5 203 ? 125.686 151.852 174.444 1.00 89.42  ? 191 PHE S CA  1 
ATOM 8302 C C   . PHE E 5 203 ? 124.385 151.324 173.855 1.00 89.72  ? 191 PHE S C   1 
ATOM 8303 O O   . PHE E 5 203 ? 124.142 150.115 173.802 1.00 89.08  ? 191 PHE S O   1 
ATOM 8304 C CB  . PHE E 5 203 ? 126.732 151.958 173.337 1.00 85.46  ? 191 PHE S CB  1 
ATOM 8305 C CG  . PHE E 5 203 ? 127.950 152.733 173.726 1.00 86.86  ? 191 PHE S CG  1 
ATOM 8306 C CD1 . PHE E 5 203 ? 127.940 154.115 173.705 1.00 87.43  ? 191 PHE S CD1 1 
ATOM 8307 C CD2 . PHE E 5 203 ? 129.110 152.081 174.101 1.00 88.70  ? 191 PHE S CD2 1 
ATOM 8308 C CE1 . PHE E 5 203 ? 129.062 154.833 174.060 1.00 88.84  ? 191 PHE S CE1 1 
ATOM 8309 C CE2 . PHE E 5 203 ? 130.236 152.794 174.455 1.00 89.24  ? 191 PHE S CE2 1 
ATOM 8310 C CZ  . PHE E 5 203 ? 130.212 154.171 174.433 1.00 88.58  ? 191 PHE S CZ  1 
ATOM 8311 N N   . SER E 5 204 ? 123.543 152.251 173.408 1.00 88.10  ? 192 SER S N   1 
ATOM 8312 C CA  . SER E 5 204 ? 122.316 151.899 172.712 1.00 87.16  ? 192 SER S CA  1 
ATOM 8313 C C   . SER E 5 204 ? 121.914 153.071 171.832 1.00 87.56  ? 192 SER S C   1 
ATOM 8314 O O   . SER E 5 204 ? 122.060 154.228 172.230 1.00 91.90  ? 192 SER S O   1 
ATOM 8315 C CB  . SER E 5 204 ? 121.190 151.552 173.692 1.00 86.89  ? 192 SER S CB  1 
ATOM 8316 O OG  . SER E 5 204 ? 119.971 151.328 173.007 1.00 88.12  ? 192 SER S OG  1 
ATOM 8317 N N   . GLY E 5 205 ? 121.412 152.765 170.645 1.00 82.68  ? 193 GLY S N   1 
ATOM 8318 C CA  . GLY E 5 205 ? 121.016 153.790 169.703 1.00 81.94  ? 193 GLY S CA  1 
ATOM 8319 C C   . GLY E 5 205 ? 119.608 153.558 169.199 1.00 83.20  ? 193 GLY S C   1 
ATOM 8320 O O   . GLY E 5 205 ? 119.117 152.430 169.155 1.00 85.69  ? 193 GLY S O   1 
ATOM 8321 N N   . SER E 5 206 ? 118.963 154.652 168.811 1.00 80.67  ? 194 SER S N   1 
ATOM 8322 C CA  . SER E 5 206 ? 117.601 154.605 168.300 1.00 83.87  ? 194 SER S CA  1 
ATOM 8323 C C   . SER E 5 206 ? 117.452 155.687 167.238 1.00 83.66  ? 194 SER S C   1 
ATOM 8324 O O   . SER E 5 206 ? 118.428 156.332 166.843 1.00 84.81  ? 194 SER S O   1 
ATOM 8325 C CB  . SER E 5 206 ? 116.589 154.765 169.441 1.00 85.06  ? 194 SER S CB  1 
ATOM 8326 O OG  . SER E 5 206 ? 116.694 156.045 170.039 1.00 88.30  ? 194 SER S OG  1 
ATOM 8327 N N   . GLY E 5 207 ? 116.232 155.883 166.775 1.00 77.38  ? 195 GLY S N   1 
ATOM 8328 C CA  . GLY E 5 207 ? 115.939 156.889 165.775 1.00 80.20  ? 195 GLY S CA  1 
ATOM 8329 C C   . GLY E 5 207 ? 114.747 156.488 164.936 1.00 83.66  ? 195 GLY S C   1 
ATOM 8330 O O   . GLY E 5 207 ? 114.321 155.335 164.907 1.00 84.01  ? 195 GLY S O   1 
ATOM 8331 N N   . SER E 5 208 ? 114.192 157.474 164.229 1.00 92.14  ? 196 SER S N   1 
ATOM 8332 C CA  . SER E 5 208 ? 113.021 157.240 163.386 1.00 90.10  ? 196 SER S CA  1 
ATOM 8333 C C   . SER E 5 208 ? 113.041 158.263 162.253 1.00 91.31  ? 196 SER S C   1 
ATOM 8334 O O   . SER E 5 208 ? 112.627 159.410 162.444 1.00 92.63  ? 196 SER S O   1 
ATOM 8335 C CB  . SER E 5 208 ? 111.736 157.333 164.197 1.00 92.06  ? 196 SER S CB  1 
ATOM 8336 O OG  . SER E 5 208 ? 111.783 158.424 165.100 1.00 92.19  ? 196 SER S OG  1 
ATOM 8337 N N   . GLY E 5 209 ? 113.520 157.841 161.086 1.00 95.38  ? 197 GLY S N   1 
ATOM 8338 C CA  . GLY E 5 209 ? 113.463 158.667 159.896 1.00 98.07  ? 197 GLY S CA  1 
ATOM 8339 C C   . GLY E 5 209 ? 114.494 159.774 159.838 1.00 96.67  ? 197 GLY S C   1 
ATOM 8340 O O   . GLY E 5 209 ? 115.444 159.704 159.052 1.00 91.15  ? 197 GLY S O   1 
ATOM 8341 N N   . THR E 5 210 ? 114.319 160.808 160.663 1.00 95.97  ? 198 THR S N   1 
ATOM 8342 C CA  . THR E 5 210 ? 115.209 161.963 160.653 1.00 95.48  ? 198 THR S CA  1 
ATOM 8343 C C   . THR E 5 210 ? 115.761 162.342 162.018 1.00 94.20  ? 198 THR S C   1 
ATOM 8344 O O   . THR E 5 210 ? 116.797 163.015 162.071 1.00 94.78  ? 198 THR S O   1 
ATOM 8345 C CB  . THR E 5 210 ? 114.497 163.191 160.062 1.00 96.19  ? 198 THR S CB  1 
ATOM 8346 O OG1 . THR E 5 210 ? 113.321 163.480 160.828 1.00 97.02  ? 198 THR S OG1 1 
ATOM 8347 C CG2 . THR E 5 210 ? 114.106 162.941 158.614 1.00 93.48  ? 198 THR S CG2 1 
ATOM 8348 N N   . ALA E 5 211 ? 115.120 161.947 163.112 1.00 89.98  ? 199 ALA S N   1 
ATOM 8349 C CA  . ALA E 5 211 ? 115.591 162.252 164.455 1.00 92.22  ? 199 ALA S CA  1 
ATOM 8350 C C   . ALA E 5 211 ? 116.169 160.990 165.076 1.00 94.74  ? 199 ALA S C   1 
ATOM 8351 O O   . ALA E 5 211 ? 115.500 159.953 165.119 1.00 95.86  ? 199 ALA S O   1 
ATOM 8352 C CB  . ALA E 5 211 ? 114.460 162.805 165.324 1.00 91.65  ? 199 ALA S CB  1 
ATOM 8353 N N   . PHE E 5 212 ? 117.405 161.083 165.558 1.00 90.28  ? 200 PHE S N   1 
ATOM 8354 C CA  . PHE E 5 212 ? 118.126 159.943 166.102 1.00 85.09  ? 200 PHE S CA  1 
ATOM 8355 C C   . PHE E 5 212 ? 118.686 160.297 167.470 1.00 83.52  ? 200 PHE S C   1 
ATOM 8356 O O   . PHE E 5 212 ? 118.968 161.462 167.757 1.00 88.41  ? 200 PHE S O   1 
ATOM 8357 C CB  . PHE E 5 212 ? 119.257 159.513 165.174 1.00 79.20  ? 200 PHE S CB  1 
ATOM 8358 C CG  . PHE E 5 212 ? 118.882 159.517 163.721 1.00 80.46  ? 200 PHE S CG  1 
ATOM 8359 C CD1 . PHE E 5 212 ? 118.140 158.481 163.181 1.00 79.49  ? 200 PHE S CD1 1 
ATOM 8360 C CD2 . PHE E 5 212 ? 119.273 160.554 162.894 1.00 86.41  ? 200 PHE S CD2 1 
ATOM 8361 C CE1 . PHE E 5 212 ? 117.794 158.480 161.845 1.00 81.76  ? 200 PHE S CE1 1 
ATOM 8362 C CE2 . PHE E 5 212 ? 118.930 160.559 161.556 1.00 89.94  ? 200 PHE S CE2 1 
ATOM 8363 C CZ  . PHE E 5 212 ? 118.189 159.521 161.032 1.00 85.68  ? 200 PHE S CZ  1 
ATOM 8364 N N   . THR E 5 213 ? 118.846 159.280 168.314 1.00 76.39  ? 201 THR S N   1 
ATOM 8365 C CA  . THR E 5 213 ? 119.289 159.484 169.685 1.00 79.34  ? 201 THR S CA  1 
ATOM 8366 C C   . THR E 5 213 ? 120.274 158.396 170.085 1.00 79.95  ? 201 THR S C   1 
ATOM 8367 O O   . THR E 5 213 ? 120.094 157.225 169.740 1.00 79.79  ? 201 THR S O   1 
ATOM 8368 C CB  . THR E 5 213 ? 118.099 159.492 170.654 1.00 80.54  ? 201 THR S CB  1 
ATOM 8369 O OG1 . THR E 5 213 ? 117.073 160.352 170.144 1.00 80.02  ? 201 THR S OG1 1 
ATOM 8370 C CG2 . THR E 5 213 ? 118.528 159.988 172.024 1.00 80.03  ? 201 THR S CG2 1 
ATOM 8371 N N   . LEU E 5 214 ? 121.316 158.794 170.811 1.00 77.86  ? 202 LEU S N   1 
ATOM 8372 C CA  . LEU E 5 214 ? 122.280 157.874 171.401 1.00 75.99  ? 202 LEU S CA  1 
ATOM 8373 C C   . LEU E 5 214 ? 122.235 158.017 172.915 1.00 80.19  ? 202 LEU S C   1 
ATOM 8374 O O   . LEU E 5 214 ? 122.314 159.133 173.438 1.00 83.17  ? 202 LEU S O   1 
ATOM 8375 C CB  . LEU E 5 214 ? 123.696 158.144 170.883 1.00 75.49  ? 202 LEU S CB  1 
ATOM 8376 C CG  . LEU E 5 214 ? 124.847 157.504 171.665 1.00 78.92  ? 202 LEU S CG  1 
ATOM 8377 C CD1 . LEU E 5 214 ? 124.731 155.994 171.670 1.00 79.58  ? 202 LEU S CD1 1 
ATOM 8378 C CD2 . LEU E 5 214 ? 126.191 157.930 171.095 1.00 78.55  ? 202 LEU S CD2 1 
ATOM 8379 N N   . THR E 5 215 ? 122.108 156.892 173.613 1.00 88.60  ? 203 THR S N   1 
ATOM 8380 C CA  . THR E 5 215 ? 122.041 156.872 175.066 1.00 88.00  ? 203 THR S CA  1 
ATOM 8381 C C   . THR E 5 215 ? 123.146 155.988 175.626 1.00 89.23  ? 203 THR S C   1 
ATOM 8382 O O   . THR E 5 215 ? 123.444 154.922 175.076 1.00 89.29  ? 203 THR S O   1 
ATOM 8383 C CB  . THR E 5 215 ? 120.671 156.379 175.556 1.00 91.96  ? 203 THR S CB  1 
ATOM 8384 O OG1 . THR E 5 215 ? 120.689 156.249 176.982 1.00 93.06  ? 203 THR S OG1 1 
ATOM 8385 C CG2 . THR E 5 215 ? 120.316 155.039 174.926 1.00 89.83  ? 203 THR S CG2 1 
ATOM 8386 N N   . ILE E 5 216 ? 123.762 156.443 176.713 1.00 101.12 ? 204 ILE S N   1 
ATOM 8387 C CA  . ILE E 5 216 ? 124.846 155.727 177.377 1.00 103.73 ? 204 ILE S CA  1 
ATOM 8388 C C   . ILE E 5 216 ? 124.454 155.547 178.836 1.00 102.96 ? 204 ILE S C   1 
ATOM 8389 O O   . ILE E 5 216 ? 124.496 156.504 179.619 1.00 101.78 ? 204 ILE S O   1 
ATOM 8390 C CB  . ILE E 5 216 ? 126.187 156.465 177.258 1.00 100.90 ? 204 ILE S CB  1 
ATOM 8391 C CG1 . ILE E 5 216 ? 126.440 156.893 175.813 1.00 99.22  ? 204 ILE S CG1 1 
ATOM 8392 C CG2 . ILE E 5 216 ? 127.322 155.589 177.761 1.00 98.53  ? 204 ILE S CG2 1 
ATOM 8393 C CD1 . ILE E 5 216 ? 127.381 158.065 175.685 1.00 99.25  ? 204 ILE S CD1 1 
ATOM 8394 N N   . SER E 5 217 ? 124.077 154.326 179.205 1.00 100.87 ? 205 SER S N   1 
ATOM 8395 C CA  . SER E 5 217 ? 123.727 154.011 180.581 1.00 99.28  ? 205 SER S CA  1 
ATOM 8396 C C   . SER E 5 217 ? 124.981 153.674 181.375 1.00 101.01 ? 205 SER S C   1 
ATOM 8397 O O   . SER E 5 217 ? 125.869 152.971 180.885 1.00 103.28 ? 205 SER S O   1 
ATOM 8398 C CB  . SER E 5 217 ? 122.743 152.841 180.634 1.00 100.27 ? 205 SER S CB  1 
ATOM 8399 O OG  . SER E 5 217 ? 121.682 153.025 179.715 1.00 101.27 ? 205 SER S OG  1 
ATOM 8400 N N   . ARG E 5 218 ? 125.047 154.185 182.606 1.00 101.37 ? 206 ARG S N   1 
ATOM 8401 C CA  . ARG E 5 218 ? 126.177 153.960 183.508 1.00 101.50 ? 206 ARG S CA  1 
ATOM 8402 C C   . ARG E 5 218 ? 127.489 154.420 182.866 1.00 102.73 ? 206 ARG S C   1 
ATOM 8403 O O   . ARG E 5 218 ? 128.398 153.631 182.601 1.00 100.43 ? 206 ARG S O   1 
ATOM 8404 C CB  . ARG E 5 218 ? 126.252 152.490 183.937 1.00 99.69  ? 206 ARG S CB  1 
ATOM 8405 N N   . LEU E 5 219 ? 127.563 155.725 182.615 1.00 109.21 ? 207 LEU S N   1 
ATOM 8406 C CA  . LEU E 5 219 ? 128.729 156.303 181.960 1.00 107.78 ? 207 LEU S CA  1 
ATOM 8407 C C   . LEU E 5 219 ? 129.974 156.130 182.822 1.00 108.71 ? 207 LEU S C   1 
ATOM 8408 O O   . LEU E 5 219 ? 129.917 156.209 184.052 1.00 110.04 ? 207 LEU S O   1 
ATOM 8409 C CB  . LEU E 5 219 ? 128.471 157.784 181.655 1.00 107.77 ? 207 LEU S CB  1 
ATOM 8410 C CG  . LEU E 5 219 ? 129.591 158.773 181.306 1.00 109.57 ? 207 LEU S CG  1 
ATOM 8411 C CD1 . LEU E 5 219 ? 129.009 159.921 180.504 1.00 110.50 ? 207 LEU S CD1 1 
ATOM 8412 C CD2 . LEU E 5 219 ? 130.275 159.332 182.548 1.00 106.86 ? 207 LEU S CD2 1 
ATOM 8413 N N   . GLU E 5 220 ? 131.105 155.890 182.165 1.00 109.24 ? 208 GLU S N   1 
ATOM 8414 C CA  . GLU E 5 220 ? 132.390 155.717 182.825 1.00 109.97 ? 208 GLU S CA  1 
ATOM 8415 C C   . GLU E 5 220 ? 133.295 156.911 182.541 1.00 111.40 ? 208 GLU S C   1 
ATOM 8416 O O   . GLU E 5 220 ? 133.021 157.741 181.671 1.00 110.14 ? 208 GLU S O   1 
ATOM 8417 C CB  . GLU E 5 220 ? 133.064 154.417 182.372 1.00 108.62 ? 208 GLU S CB  1 
ATOM 8418 N N   . ALA E 5 221 ? 134.394 156.982 183.295 1.00 118.52 ? 209 ALA S N   1 
ATOM 8419 C CA  . ALA E 5 221 ? 135.329 158.093 183.157 1.00 119.28 ? 209 ALA S CA  1 
ATOM 8420 C C   . ALA E 5 221 ? 136.120 158.038 181.856 1.00 119.22 ? 209 ALA S C   1 
ATOM 8421 O O   . ALA E 5 221 ? 136.580 159.082 181.382 1.00 117.28 ? 209 ALA S O   1 
ATOM 8422 C CB  . ALA E 5 221 ? 136.288 158.123 184.348 1.00 118.80 ? 209 ALA S CB  1 
ATOM 8423 N N   . GLU E 5 222 ? 136.284 156.855 181.269 1.00 112.23 ? 210 GLU S N   1 
ATOM 8424 C CA  . GLU E 5 222 ? 136.995 156.702 180.007 1.00 109.82 ? 210 GLU S CA  1 
ATOM 8425 C C   . GLU E 5 222 ? 136.115 156.981 178.797 1.00 110.22 ? 210 GLU S C   1 
ATOM 8426 O O   . GLU E 5 222 ? 136.580 156.829 177.663 1.00 110.81 ? 210 GLU S O   1 
ATOM 8427 C CB  . GLU E 5 222 ? 137.576 155.288 179.897 1.00 109.10 ? 210 GLU S CB  1 
ATOM 8428 C CG  . GLU E 5 222 ? 136.520 154.192 179.877 1.00 110.67 ? 210 GLU S CG  1 
ATOM 8429 C CD  . GLU E 5 222 ? 136.213 153.696 178.476 1.00 111.28 ? 210 GLU S CD  1 
ATOM 8430 O OE1 . GLU E 5 222 ? 137.042 153.917 177.569 1.00 111.43 ? 210 GLU S OE1 1 
ATOM 8431 O OE2 . GLU E 5 222 ? 135.138 153.088 178.281 1.00 109.39 ? 210 GLU S OE2 1 
ATOM 8432 N N   . ASP E 5 223 ? 134.864 157.383 179.012 1.00 101.24 ? 211 ASP S N   1 
ATOM 8433 C CA  . ASP E 5 223 ? 133.881 157.535 177.949 1.00 99.66  ? 211 ASP S CA  1 
ATOM 8434 C C   . ASP E 5 223 ? 133.760 158.975 177.454 1.00 101.24 ? 211 ASP S C   1 
ATOM 8435 O O   . ASP E 5 223 ? 133.014 159.235 176.506 1.00 100.52 ? 211 ASP S O   1 
ATOM 8436 C CB  . ASP E 5 223 ? 132.527 157.012 178.444 1.00 100.52 ? 211 ASP S CB  1 
ATOM 8437 C CG  . ASP E 5 223 ? 131.484 156.913 177.346 1.00 102.72 ? 211 ASP S CG  1 
ATOM 8438 O OD1 . ASP E 5 223 ? 131.295 155.804 176.807 1.00 104.17 ? 211 ASP S OD1 1 
ATOM 8439 O OD2 . ASP E 5 223 ? 130.813 157.925 177.060 1.00 100.75 ? 211 ASP S OD2 1 
ATOM 8440 N N   . VAL E 5 224 ? 134.507 159.910 178.041 1.00 107.72 ? 212 VAL S N   1 
ATOM 8441 C CA  . VAL E 5 224 ? 134.397 161.304 177.629 1.00 107.25 ? 212 VAL S CA  1 
ATOM 8442 C C   . VAL E 5 224 ? 135.066 161.501 176.273 1.00 105.08 ? 212 VAL S C   1 
ATOM 8443 O O   . VAL E 5 224 ? 136.023 160.801 175.913 1.00 105.19 ? 212 VAL S O   1 
ATOM 8444 C CB  . VAL E 5 224 ? 135.004 162.238 178.692 1.00 104.88 ? 212 VAL S CB  1 
ATOM 8445 C CG1 . VAL E 5 224 ? 134.209 162.153 179.988 1.00 105.39 ? 212 VAL S CG1 1 
ATOM 8446 C CG2 . VAL E 5 224 ? 136.467 161.898 178.930 1.00 102.15 ? 212 VAL S CG2 1 
ATOM 8447 N N   . GLY E 5 225 ? 134.557 162.460 175.509 1.00 95.00  ? 213 GLY S N   1 
ATOM 8448 C CA  . GLY E 5 225 ? 135.101 162.744 174.193 1.00 94.07  ? 213 GLY S CA  1 
ATOM 8449 C C   . GLY E 5 225 ? 134.087 163.499 173.349 1.00 95.72  ? 213 GLY S C   1 
ATOM 8450 O O   . GLY E 5 225 ? 133.148 164.096 173.871 1.00 97.43  ? 213 GLY S O   1 
ATOM 8451 N N   . VAL E 5 226 ? 134.305 163.450 172.037 1.00 85.53  ? 214 VAL S N   1 
ATOM 8452 C CA  . VAL E 5 226 ? 133.449 164.109 171.056 1.00 82.76  ? 214 VAL S CA  1 
ATOM 8453 C C   . VAL E 5 226 ? 132.734 163.035 170.248 1.00 85.73  ? 214 VAL S C   1 
ATOM 8454 O O   . VAL E 5 226 ? 133.375 162.113 169.729 1.00 87.25  ? 214 VAL S O   1 
ATOM 8455 C CB  . VAL E 5 226 ? 134.257 165.040 170.137 1.00 77.94  ? 214 VAL S CB  1 
ATOM 8456 C CG1 . VAL E 5 226 ? 133.324 165.915 169.317 1.00 74.89  ? 214 VAL S CG1 1 
ATOM 8457 C CG2 . VAL E 5 226 ? 135.216 165.889 170.954 1.00 83.38  ? 214 VAL S CG2 1 
ATOM 8458 N N   . TYR E 5 227 ? 131.410 163.153 170.141 1.00 78.82  ? 215 TYR S N   1 
ATOM 8459 C CA  . TYR E 5 227 ? 130.573 162.145 169.494 1.00 75.20  ? 215 TYR S CA  1 
ATOM 8460 C C   . TYR E 5 227 ? 130.100 162.684 168.149 1.00 77.35  ? 215 TYR S C   1 
ATOM 8461 O O   . TYR E 5 227 ? 129.407 163.705 168.091 1.00 82.37  ? 215 TYR S O   1 
ATOM 8462 C CB  . TYR E 5 227 ? 129.381 161.769 170.374 1.00 74.12  ? 215 TYR S CB  1 
ATOM 8463 C CG  . TYR E 5 227 ? 129.731 161.015 171.641 1.00 78.14  ? 215 TYR S CG  1 
ATOM 8464 C CD1 . TYR E 5 227 ? 130.602 161.552 172.581 1.00 75.38  ? 215 TYR S CD1 1 
ATOM 8465 C CD2 . TYR E 5 227 ? 129.200 159.759 171.888 1.00 79.79  ? 215 TYR S CD2 1 
ATOM 8466 C CE1 . TYR E 5 227 ? 130.919 160.865 173.735 1.00 78.45  ? 215 TYR S CE1 1 
ATOM 8467 C CE2 . TYR E 5 227 ? 129.514 159.064 173.037 1.00 81.53  ? 215 TYR S CE2 1 
ATOM 8468 C CZ  . TYR E 5 227 ? 130.372 159.623 173.957 1.00 81.63  ? 215 TYR S CZ  1 
ATOM 8469 O OH  . TYR E 5 227 ? 130.688 158.932 175.103 1.00 84.06  ? 215 TYR S OH  1 
ATOM 8470 N N   . TYR E 5 228 ? 130.463 161.992 167.073 1.00 59.25  ? 216 TYR S N   1 
ATOM 8471 C CA  . TYR E 5 228 ? 130.125 162.399 165.716 1.00 62.02  ? 216 TYR S CA  1 
ATOM 8472 C C   . TYR E 5 228 ? 129.103 161.435 165.130 1.00 64.33  ? 216 TYR S C   1 
ATOM 8473 O O   . TYR E 5 228 ? 129.251 160.216 165.260 1.00 65.98  ? 216 TYR S O   1 
ATOM 8474 C CB  . TYR E 5 228 ? 131.374 162.436 164.833 1.00 62.16  ? 216 TYR S CB  1 
ATOM 8475 C CG  . TYR E 5 228 ? 132.405 163.451 165.265 1.00 64.54  ? 216 TYR S CG  1 
ATOM 8476 C CD1 . TYR E 5 228 ? 132.274 164.790 164.923 1.00 68.11  ? 216 TYR S CD1 1 
ATOM 8477 C CD2 . TYR E 5 228 ? 133.508 163.073 166.015 1.00 60.32  ? 216 TYR S CD2 1 
ATOM 8478 C CE1 . TYR E 5 228 ? 133.214 165.721 165.315 1.00 65.20  ? 216 TYR S CE1 1 
ATOM 8479 C CE2 . TYR E 5 228 ? 134.453 163.997 166.412 1.00 62.38  ? 216 TYR S CE2 1 
ATOM 8480 C CZ  . TYR E 5 228 ? 134.301 165.319 166.059 1.00 65.02  ? 216 TYR S CZ  1 
ATOM 8481 O OH  . TYR E 5 228 ? 135.239 166.243 166.454 1.00 69.72  ? 216 TYR S OH  1 
ATOM 8482 N N   . CYS E 5 229 ? 128.073 161.980 164.487 1.00 60.83  ? 217 CYS S N   1 
ATOM 8483 C CA  . CYS E 5 229 ? 127.092 161.184 163.761 1.00 56.15  ? 217 CYS S CA  1 
ATOM 8484 C C   . CYS E 5 229 ? 127.214 161.480 162.273 1.00 53.63  ? 217 CYS S C   1 
ATOM 8485 O O   . CYS E 5 229 ? 127.203 162.645 161.864 1.00 66.02  ? 217 CYS S O   1 
ATOM 8486 C CB  . CYS E 5 229 ? 125.667 161.451 164.261 1.00 58.67  ? 217 CYS S CB  1 
ATOM 8487 S SG  . CYS E 5 229 ? 124.962 163.083 163.922 1.00 69.13  ? 217 CYS S SG  1 
ATOM 8488 N N   . MET E 5 230 ? 127.344 160.425 161.473 1.00 34.04  ? 218 MET S N   1 
ATOM 8489 C CA  . MET E 5 230 ? 127.594 160.539 160.044 1.00 44.82  ? 218 MET S CA  1 
ATOM 8490 C C   . MET E 5 230 ? 126.560 159.729 159.278 1.00 42.19  ? 218 MET S C   1 
ATOM 8491 O O   . MET E 5 230 ? 126.128 158.668 159.738 1.00 56.25  ? 218 MET S O   1 
ATOM 8492 C CB  . MET E 5 230 ? 129.008 160.050 159.694 1.00 53.63  ? 218 MET S CB  1 
ATOM 8493 C CG  . MET E 5 230 ? 129.290 159.933 158.204 1.00 55.13  ? 218 MET S CG  1 
ATOM 8494 S SD  . MET E 5 230 ? 130.579 158.737 157.822 1.00 47.57  ? 218 MET S SD  1 
ATOM 8495 C CE  . MET E 5 230 ? 129.603 157.245 157.695 1.00 51.25  ? 218 MET S CE  1 
ATOM 8496 N N   . GLN E 5 231 ? 126.165 160.230 158.112 1.00 40.51  ? 219 GLN S N   1 
ATOM 8497 C CA  . GLN E 5 231 ? 125.228 159.539 157.239 1.00 40.31  ? 219 GLN S CA  1 
ATOM 8498 C C   . GLN E 5 231 ? 125.979 158.892 156.084 1.00 44.74  ? 219 GLN S C   1 
ATOM 8499 O O   . GLN E 5 231 ? 126.934 159.464 155.552 1.00 60.90  ? 219 GLN S O   1 
ATOM 8500 C CB  . GLN E 5 231 ? 124.167 160.500 156.699 1.00 52.11  ? 219 GLN S CB  1 
ATOM 8501 C CG  . GLN E 5 231 ? 124.722 161.705 155.959 1.00 55.67  ? 219 GLN S CG  1 
ATOM 8502 C CD  . GLN E 5 231 ? 124.883 161.451 154.473 1.00 60.22  ? 219 GLN S CD  1 
ATOM 8503 O OE1 . GLN E 5 231 ? 124.369 160.467 153.942 1.00 59.22  ? 219 GLN S OE1 1 
ATOM 8504 N NE2 . GLN E 5 231 ? 125.599 162.338 153.794 1.00 60.01  ? 219 GLN S NE2 1 
ATOM 8505 N N   . HIS E 5 232 ? 125.545 157.692 155.701 1.00 43.87  ? 220 HIS S N   1 
ATOM 8506 C CA  . HIS E 5 232 ? 126.150 156.962 154.593 1.00 46.40  ? 220 HIS S CA  1 
ATOM 8507 C C   . HIS E 5 232 ? 125.142 156.661 153.491 1.00 54.39  ? 220 HIS S C   1 
ATOM 8508 O O   . HIS E 5 232 ? 125.390 155.792 152.650 1.00 62.38  ? 220 HIS S O   1 
ATOM 8509 C CB  . HIS E 5 232 ? 126.787 155.664 155.092 1.00 42.00  ? 220 HIS S CB  1 
ATOM 8510 C CG  . HIS E 5 232 ? 127.950 155.206 154.269 1.00 39.80  ? 220 HIS S CG  1 
ATOM 8511 N ND1 . HIS E 5 232 ? 127.810 154.362 153.190 1.00 44.48  ? 220 HIS S ND1 1 
ATOM 8512 C CD2 . HIS E 5 232 ? 129.273 155.466 154.373 1.00 49.20  ? 220 HIS S CD2 1 
ATOM 8513 C CE1 . HIS E 5 232 ? 128.996 154.126 152.661 1.00 42.63  ? 220 HIS S CE1 1 
ATOM 8514 N NE2 . HIS E 5 232 ? 129.902 154.784 153.361 1.00 48.10  ? 220 HIS S NE2 1 
ATOM 8515 N N   . LEU E 5 233 ? 124.006 157.360 153.485 1.00 57.73  ? 221 LEU S N   1 
ATOM 8516 C CA  . LEU E 5 233 ? 122.965 157.074 152.503 1.00 55.66  ? 221 LEU S CA  1 
ATOM 8517 C C   . LEU E 5 233 ? 123.427 157.390 151.086 1.00 56.03  ? 221 LEU S C   1 
ATOM 8518 O O   . LEU E 5 233 ? 123.163 156.618 150.157 1.00 60.96  ? 221 LEU S O   1 
ATOM 8519 C CB  . LEU E 5 233 ? 121.700 157.860 152.843 1.00 55.17  ? 221 LEU S CB  1 
ATOM 8520 C CG  . LEU E 5 233 ? 120.526 157.685 151.883 1.00 54.75  ? 221 LEU S CG  1 
ATOM 8521 C CD1 . LEU E 5 233 ? 120.029 156.253 151.918 1.00 58.39  ? 221 LEU S CD1 1 
ATOM 8522 C CD2 . LEU E 5 233 ? 119.409 158.649 152.237 1.00 63.64  ? 221 LEU S CD2 1 
ATOM 8523 N N   . GLU E 5 234 ? 124.119 158.510 150.900 1.00 55.86  ? 222 GLU S N   1 
ATOM 8524 C CA  . GLU E 5 234 ? 124.524 158.931 149.567 1.00 57.76  ? 222 GLU S CA  1 
ATOM 8525 C C   . GLU E 5 234 ? 125.729 159.853 149.684 1.00 52.95  ? 222 GLU S C   1 
ATOM 8526 O O   . GLU E 5 234 ? 125.800 160.677 150.599 1.00 53.90  ? 222 GLU S O   1 
ATOM 8527 C CB  . GLU E 5 234 ? 123.372 159.637 148.841 1.00 64.93  ? 222 GLU S CB  1 
ATOM 8528 C CG  . GLU E 5 234 ? 123.617 159.906 147.367 1.00 62.12  ? 222 GLU S CG  1 
ATOM 8529 C CD  . GLU E 5 234 ? 122.430 160.575 146.698 1.00 68.30  ? 222 GLU S CD  1 
ATOM 8530 O OE1 . GLU E 5 234 ? 121.439 160.870 147.400 1.00 64.75  ? 222 GLU S OE1 1 
ATOM 8531 O OE2 . GLU E 5 234 ? 122.483 160.801 145.471 1.00 69.21  ? 222 GLU S OE2 1 
ATOM 8532 N N   . TYR E 5 235 ? 126.667 159.706 148.753 1.00 55.40  ? 223 TYR S N   1 
ATOM 8533 C CA  . TYR E 5 235 ? 127.863 160.530 148.760 1.00 57.21  ? 223 TYR S CA  1 
ATOM 8534 C C   . TYR E 5 235 ? 127.527 161.962 148.343 1.00 58.05  ? 223 TYR S C   1 
ATOM 8535 O O   . TYR E 5 235 ? 126.597 162.188 147.565 1.00 59.96  ? 223 TYR S O   1 
ATOM 8536 C CB  . TYR E 5 235 ? 128.914 159.943 147.823 1.00 54.03  ? 223 TYR S CB  1 
ATOM 8537 C CG  . TYR E 5 235 ? 129.462 158.616 148.292 1.00 53.51  ? 223 TYR S CG  1 
ATOM 8538 C CD1 . TYR E 5 235 ? 130.404 158.552 149.308 1.00 52.51  ? 223 TYR S CD1 1 
ATOM 8539 C CD2 . TYR E 5 235 ? 129.025 157.427 147.730 1.00 55.42  ? 223 TYR S CD2 1 
ATOM 8540 C CE1 . TYR E 5 235 ? 130.902 157.342 149.742 1.00 51.97  ? 223 TYR S CE1 1 
ATOM 8541 C CE2 . TYR E 5 235 ? 129.518 156.213 148.157 1.00 52.94  ? 223 TYR S CE2 1 
ATOM 8542 C CZ  . TYR E 5 235 ? 130.455 156.176 149.163 1.00 52.41  ? 223 TYR S CZ  1 
ATOM 8543 O OH  . TYR E 5 235 ? 130.946 154.965 149.591 1.00 59.49  ? 223 TYR S OH  1 
ATOM 8544 N N   . PRO E 5 236 ? 128.272 162.954 148.851 1.00 54.30  ? 224 PRO S N   1 
ATOM 8545 C CA  . PRO E 5 236 ? 129.402 162.850 149.784 1.00 48.39  ? 224 PRO S CA  1 
ATOM 8546 C C   . PRO E 5 236 ? 128.957 162.616 151.222 1.00 52.81  ? 224 PRO S C   1 
ATOM 8547 O O   . PRO E 5 236 ? 127.942 163.148 151.661 1.00 55.96  ? 224 PRO S O   1 
ATOM 8548 C CB  . PRO E 5 236 ? 130.100 164.204 149.615 1.00 47.19  ? 224 PRO S CB  1 
ATOM 8549 C CG  . PRO E 5 236 ? 128.974 165.150 149.326 1.00 49.96  ? 224 PRO S CG  1 
ATOM 8550 C CD  . PRO E 5 236 ? 127.987 164.357 148.497 1.00 56.63  ? 224 PRO S CD  1 
ATOM 8551 N N   . LEU E 5 237 ? 129.707 161.815 151.974 1.00 43.67  ? 225 LEU S N   1 
ATOM 8552 C CA  . LEU E 5 237 ? 129.381 161.578 153.372 1.00 42.17  ? 225 LEU S CA  1 
ATOM 8553 C C   . LEU E 5 237 ? 129.581 162.853 154.178 1.00 48.57  ? 225 LEU S C   1 
ATOM 8554 O O   . LEU E 5 237 ? 130.566 163.573 153.999 1.00 59.12  ? 225 LEU S O   1 
ATOM 8555 C CB  . LEU E 5 237 ? 130.248 160.455 153.936 1.00 39.79  ? 225 LEU S CB  1 
ATOM 8556 C CG  . LEU E 5 237 ? 130.441 159.238 153.032 1.00 35.67  ? 225 LEU S CG  1 
ATOM 8557 C CD1 . LEU E 5 237 ? 131.298 158.199 153.724 1.00 49.28  ? 225 LEU S CD1 1 
ATOM 8558 C CD2 . LEU E 5 237 ? 129.103 158.647 152.637 1.00 35.75  ? 225 LEU S CD2 1 
ATOM 8559 N N   . THR E 5 238 ? 128.638 163.134 155.070 1.00 38.72  ? 226 THR S N   1 
ATOM 8560 C CA  . THR E 5 238 ? 128.666 164.351 155.865 1.00 40.88  ? 226 THR S CA  1 
ATOM 8561 C C   . THR E 5 238 ? 128.608 164.000 157.342 1.00 38.80  ? 226 THR S C   1 
ATOM 8562 O O   . THR E 5 238 ? 127.834 163.131 157.753 1.00 50.22  ? 226 THR S O   1 
ATOM 8563 C CB  . THR E 5 238 ? 127.505 165.279 155.504 1.00 56.91  ? 226 THR S CB  1 
ATOM 8564 O OG1 . THR E 5 238 ? 127.217 165.160 154.106 1.00 59.33  ? 226 THR S OG1 1 
ATOM 8565 C CG2 . THR E 5 238 ? 127.863 166.723 155.817 1.00 55.58  ? 226 THR S CG2 1 
ATOM 8566 N N   . PHE E 5 239 ? 129.428 164.680 158.133 1.00 44.89  ? 227 PHE S N   1 
ATOM 8567 C CA  . PHE E 5 239 ? 129.484 164.481 159.572 1.00 51.53  ? 227 PHE S CA  1 
ATOM 8568 C C   . PHE E 5 239 ? 128.715 165.582 160.291 1.00 55.65  ? 227 PHE S C   1 
ATOM 8569 O O   . PHE E 5 239 ? 128.409 166.634 159.726 1.00 60.47  ? 227 PHE S O   1 
ATOM 8570 C CB  . PHE E 5 239 ? 130.935 164.456 160.061 1.00 51.94  ? 227 PHE S CB  1 
ATOM 8571 C CG  . PHE E 5 239 ? 131.654 163.172 159.766 1.00 53.00  ? 227 PHE S CG  1 
ATOM 8572 C CD1 . PHE E 5 239 ? 132.041 162.858 158.476 1.00 51.61  ? 227 PHE S CD1 1 
ATOM 8573 C CD2 . PHE E 5 239 ? 131.947 162.280 160.782 1.00 52.13  ? 227 PHE S CD2 1 
ATOM 8574 C CE1 . PHE E 5 239 ? 132.702 161.680 158.204 1.00 44.90  ? 227 PHE S CE1 1 
ATOM 8575 C CE2 . PHE E 5 239 ? 132.609 161.101 160.515 1.00 47.74  ? 227 PHE S CE2 1 
ATOM 8576 C CZ  . PHE E 5 239 ? 132.986 160.801 159.225 1.00 48.83  ? 227 PHE S CZ  1 
ATOM 8577 N N   . GLY E 5 240 ? 128.401 165.322 161.556 1.00 57.00  ? 228 GLY S N   1 
ATOM 8578 C CA  . GLY E 5 240 ? 127.748 166.316 162.376 1.00 59.54  ? 228 GLY S CA  1 
ATOM 8579 C C   . GLY E 5 240 ? 128.724 167.332 162.932 1.00 64.48  ? 228 GLY S C   1 
ATOM 8580 O O   . GLY E 5 240 ? 129.937 167.238 162.751 1.00 72.02  ? 228 GLY S O   1 
ATOM 8581 N N   . ALA E 5 241 ? 128.168 168.330 163.621 1.00 70.48  ? 229 ALA S N   1 
ATOM 8582 C CA  . ALA E 5 241 ? 129.003 169.360 164.229 1.00 71.09  ? 229 ALA S CA  1 
ATOM 8583 C C   . ALA E 5 241 ? 129.915 168.772 165.298 1.00 70.95  ? 229 ALA S C   1 
ATOM 8584 O O   . ALA E 5 241 ? 131.092 169.140 165.393 1.00 71.88  ? 229 ALA S O   1 
ATOM 8585 C CB  . ALA E 5 241 ? 128.128 170.467 164.817 1.00 72.31  ? 229 ALA S CB  1 
ATOM 8586 N N   . GLY E 5 242 ? 129.392 167.858 166.112 1.00 76.23  ? 230 GLY S N   1 
ATOM 8587 C CA  . GLY E 5 242 ? 130.184 167.231 167.150 1.00 74.66  ? 230 GLY S CA  1 
ATOM 8588 C C   . GLY E 5 242 ? 129.776 167.645 168.548 1.00 81.14  ? 230 GLY S C   1 
ATOM 8589 O O   . GLY E 5 242 ? 129.876 168.821 168.908 1.00 83.87  ? 230 GLY S O   1 
ATOM 8590 N N   . THR E 5 243 ? 129.315 166.687 169.346 1.00 88.36  ? 231 THR S N   1 
ATOM 8591 C CA  . THR E 5 243 ? 128.916 166.935 170.724 1.00 86.94  ? 231 THR S CA  1 
ATOM 8592 C C   . THR E 5 243 ? 130.011 166.445 171.660 1.00 89.52  ? 231 THR S C   1 
ATOM 8593 O O   . THR E 5 243 ? 130.415 165.280 171.595 1.00 90.40  ? 231 THR S O   1 
ATOM 8594 C CB  . THR E 5 243 ? 127.594 166.236 171.047 1.00 88.23  ? 231 THR S CB  1 
ATOM 8595 O OG1 . THR E 5 243 ? 126.516 166.930 170.407 1.00 90.51  ? 231 THR S OG1 1 
ATOM 8596 C CG2 . THR E 5 243 ? 127.353 166.216 172.549 1.00 88.17  ? 231 THR S CG2 1 
ATOM 8597 N N   . LYS E 5 244 ? 130.485 167.333 172.528 1.00 102.03 ? 232 LYS S N   1 
ATOM 8598 C CA  . LYS E 5 244 ? 131.563 167.025 173.455 1.00 104.54 ? 232 LYS S CA  1 
ATOM 8599 C C   . LYS E 5 244 ? 131.003 166.783 174.850 1.00 104.30 ? 232 LYS S C   1 
ATOM 8600 O O   . LYS E 5 244 ? 130.157 167.542 175.332 1.00 104.44 ? 232 LYS S O   1 
ATOM 8601 C CB  . LYS E 5 244 ? 132.591 168.159 173.492 1.00 103.17 ? 232 LYS S CB  1 
ATOM 8602 C CG  . LYS E 5 244 ? 133.546 168.095 174.674 1.00 101.90 ? 232 LYS S CG  1 
ATOM 8603 C CD  . LYS E 5 244 ? 134.950 168.516 174.278 1.00 101.20 ? 232 LYS S CD  1 
ATOM 8604 C CE  . LYS E 5 244 ? 135.035 170.016 174.056 1.00 105.51 ? 232 LYS S CE  1 
ATOM 8605 N NZ  . LYS E 5 244 ? 136.446 170.488 174.009 1.00 104.77 ? 232 LYS S NZ  1 
ATOM 8606 N N   . LEU E 5 245 ? 131.476 165.720 175.491 1.00 110.43 ? 233 LEU S N   1 
ATOM 8607 C CA  . LEU E 5 245 ? 131.087 165.387 176.854 1.00 109.33 ? 233 LEU S CA  1 
ATOM 8608 C C   . LEU E 5 245 ? 132.108 165.964 177.824 1.00 110.57 ? 233 LEU S C   1 
ATOM 8609 O O   . LEU E 5 245 ? 133.318 165.815 177.621 1.00 112.10 ? 233 LEU S O   1 
ATOM 8610 C CB  . LEU E 5 245 ? 130.975 163.873 177.039 1.00 108.42 ? 233 LEU S CB  1 
ATOM 8611 C CG  . LEU E 5 245 ? 129.766 163.186 176.401 1.00 109.87 ? 233 LEU S CG  1 
ATOM 8612 C CD1 . LEU E 5 245 ? 129.483 161.861 177.093 1.00 109.66 ? 233 LEU S CD1 1 
ATOM 8613 C CD2 . LEU E 5 245 ? 128.542 164.087 176.440 1.00 109.59 ? 233 LEU S CD2 1 
ATOM 8614 N N   . GLU E 5 246 ? 131.620 166.621 178.872 1.00 121.31 ? 234 GLU S N   1 
ATOM 8615 C CA  . GLU E 5 246 ? 132.470 167.255 179.868 1.00 121.74 ? 234 GLU S CA  1 
ATOM 8616 C C   . GLU E 5 246 ? 132.292 166.569 181.215 1.00 123.11 ? 234 GLU S C   1 
ATOM 8617 O O   . GLU E 5 246 ? 131.215 166.057 181.535 1.00 123.22 ? 234 GLU S O   1 
ATOM 8618 C CB  . GLU E 5 246 ? 132.155 168.750 179.998 1.00 120.88 ? 234 GLU S CB  1 
ATOM 8619 C CG  . GLU E 5 246 ? 132.604 169.587 178.812 1.00 121.36 ? 234 GLU S CG  1 
ATOM 8620 C CD  . GLU E 5 246 ? 134.111 169.703 178.716 1.00 122.95 ? 234 GLU S CD  1 
ATOM 8621 O OE1 . GLU E 5 246 ? 134.788 169.566 179.757 1.00 121.47 ? 234 GLU S OE1 1 
ATOM 8622 O OE2 . GLU E 5 246 ? 134.620 169.932 177.599 1.00 124.32 ? 234 GLU S OE2 1 
ATOM 8623 N N   . LEU E 5 247 ? 133.364 166.562 182.001 1.00 125.09 ? 235 LEU S N   1 
ATOM 8624 C CA  . LEU E 5 247 ? 133.347 165.932 183.314 1.00 124.56 ? 235 LEU S CA  1 
ATOM 8625 C C   . LEU E 5 247 ? 134.031 166.819 184.350 1.00 124.12 ? 235 LEU S C   1 
ATOM 8626 O O   . LEU E 5 247 ? 135.208 167.152 184.215 1.00 123.68 ? 235 LEU S O   1 
ATOM 8627 C CB  . LEU E 5 247 ? 134.025 164.561 183.258 1.00 124.81 ? 235 LEU S CB  1 
ATOM 8628 C CG  . LEU E 5 247 ? 134.425 163.928 184.592 1.00 125.10 ? 235 LEU S CG  1 
ATOM 8629 C CD1 . LEU E 5 247 ? 133.196 163.645 185.443 1.00 125.41 ? 235 LEU S CD1 1 
ATOM 8630 C CD2 . LEU E 5 247 ? 135.228 162.658 184.363 1.00 124.56 ? 235 LEU S CD2 1 
# 
