data_8XXF
# 
_entry.id   8XXF 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XXF         pdb_00008xxf 10.2210/pdb8xxf/pdb 
WWPDB D_1300044207 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XXF 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yl521gl@ustc.edu.cn 
_pdbx_contact_author.name_first         Lin 
_pdbx_contact_author.name_last          Yang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1550-6947 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, L.'   1 0000-0003-1550-6947 
'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'TtCS, oxaloacetate, acetyl-CoA complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, L.'   1 0000-0003-1550-6947 
primary 'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Citrate synthase'   51100.664 6   2.3.3.16 ? ? ? 
2 non-polymer syn 'OXALOACETATE ION'   131.064   5   ?        ? ? ? 
3 non-polymer syn 'ACETYL COENZYME *A' 809.571   2   ?        ? ? ? 
4 non-polymer syn 'COENZYME A'         767.534   1   ?        ? ? ? 
5 water       nat water                18.015    883 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        CS 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGSKLAAALE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGSKLAAALE
;
_entity_poly.pdbx_strand_id                 A,B,C,D,E,F 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'OXALOACETATE ION'   OAA 
3 'ACETYL COENZYME *A' ACO 
4 'COENZYME A'         COA 
5 water                HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   LEU n 
1 4   LYS n 
1 5   GLU n 
1 6   ARG n 
1 7   LEU n 
1 8   ALA n 
1 9   GLU n 
1 10  LEU n 
1 11  ILE n 
1 12  PRO n 
1 13  GLN n 
1 14  TRP n 
1 15  ARG n 
1 16  ALA n 
1 17  GLU n 
1 18  VAL n 
1 19  ALA n 
1 20  GLU n 
1 21  ILE n 
1 22  ARG n 
1 23  LYS n 
1 24  LYS n 
1 25  TYR n 
1 26  GLY n 
1 27  ASN n 
1 28  ARG n 
1 29  LYS n 
1 30  THR n 
1 31  MET n 
1 32  ASP n 
1 33  CYS n 
1 34  THR n 
1 35  ILE n 
1 36  GLY n 
1 37  HIS n 
1 38  ALA n 
1 39  TYR n 
1 40  GLY n 
1 41  GLY n 
1 42  MET n 
1 43  ARG n 
1 44  GLY n 
1 45  LEU n 
1 46  LYS n 
1 47  ALA n 
1 48  LEU n 
1 49  VAL n 
1 50  CYS n 
1 51  ASP n 
1 52  THR n 
1 53  SER n 
1 54  GLU n 
1 55  VAL n 
1 56  PHE n 
1 57  PRO n 
1 58  ASP n 
1 59  GLU n 
1 60  GLY n 
1 61  VAL n 
1 62  LYS n 
1 63  PHE n 
1 64  ARG n 
1 65  GLY n 
1 66  TYR n 
1 67  THR n 
1 68  ILE n 
1 69  PRO n 
1 70  GLU n 
1 71  LEU n 
1 72  ARG n 
1 73  GLU n 
1 74  GLY n 
1 75  PRO n 
1 76  HIS n 
1 77  LYS n 
1 78  LEU n 
1 79  PRO n 
1 80  THR n 
1 81  ALA n 
1 82  GLU n 
1 83  GLY n 
1 84  GLY n 
1 85  PHE n 
1 86  GLU n 
1 87  PRO n 
1 88  LEU n 
1 89  PRO n 
1 90  GLU n 
1 91  GLY n 
1 92  LEU n 
1 93  TRP n 
1 94  TYR n 
1 95  LEU n 
1 96  LEU n 
1 97  LEU n 
1 98  THR n 
1 99  GLY n 
1 100 GLU n 
1 101 LEU n 
1 102 PRO n 
1 103 THR n 
1 104 GLU n 
1 105 GLU n 
1 106 ASP n 
1 107 VAL n 
1 108 LYS n 
1 109 GLU n 
1 110 ILE n 
1 111 SER n 
1 112 ALA n 
1 113 GLU n 
1 114 PHE n 
1 115 THR n 
1 116 LYS n 
1 117 ARG n 
1 118 MET n 
1 119 GLN n 
1 120 ASN n 
1 121 VAL n 
1 122 PRO n 
1 123 GLN n 
1 124 TYR n 
1 125 VAL n 
1 126 PHE n 
1 127 ASP n 
1 128 VAL n 
1 129 LEU n 
1 130 ARG n 
1 131 ALA n 
1 132 MET n 
1 133 PRO n 
1 134 VAL n 
1 135 ASP n 
1 136 THR n 
1 137 HIS n 
1 138 PRO n 
1 139 MET n 
1 140 THR n 
1 141 MET n 
1 142 PHE n 
1 143 ALA n 
1 144 ALA n 
1 145 GLY n 
1 146 ILE n 
1 147 LEU n 
1 148 ALA n 
1 149 MET n 
1 150 GLN n 
1 151 ARG n 
1 152 GLU n 
1 153 SER n 
1 154 VAL n 
1 155 PHE n 
1 156 ALA n 
1 157 LYS n 
1 158 ARG n 
1 159 TYR n 
1 160 GLU n 
1 161 GLU n 
1 162 GLY n 
1 163 MET n 
1 164 ARG n 
1 165 ARG n 
1 166 GLU n 
1 167 GLU n 
1 168 HIS n 
1 169 TRP n 
1 170 GLU n 
1 171 ALA n 
1 172 MET n 
1 173 LEU n 
1 174 GLU n 
1 175 ASP n 
1 176 SER n 
1 177 LEU n 
1 178 ASN n 
1 179 MET n 
1 180 LEU n 
1 181 ALA n 
1 182 ALA n 
1 183 LEU n 
1 184 PRO n 
1 185 VAL n 
1 186 ILE n 
1 187 ALA n 
1 188 ALA n 
1 189 TYR n 
1 190 ILE n 
1 191 TYR n 
1 192 ARG n 
1 193 ARG n 
1 194 LYS n 
1 195 TYR n 
1 196 LYS n 
1 197 GLY n 
1 198 ASP n 
1 199 THR n 
1 200 HIS n 
1 201 ILE n 
1 202 ALA n 
1 203 PRO n 
1 204 ASP n 
1 205 PRO n 
1 206 ASN n 
1 207 LEU n 
1 208 ASP n 
1 209 TRP n 
1 210 SER n 
1 211 ALA n 
1 212 ASN n 
1 213 LEU n 
1 214 ALA n 
1 215 HIS n 
1 216 MET n 
1 217 MET n 
1 218 GLY n 
1 219 PHE n 
1 220 ASP n 
1 221 ASP n 
1 222 PHE n 
1 223 GLU n 
1 224 VAL n 
1 225 TYR n 
1 226 GLU n 
1 227 LEU n 
1 228 PHE n 
1 229 ARG n 
1 230 LEU n 
1 231 TYR n 
1 232 MET n 
1 233 PHE n 
1 234 LEU n 
1 235 HIS n 
1 236 SER n 
1 237 ASP n 
1 238 HIS n 
1 239 GLU n 
1 240 GLY n 
1 241 GLY n 
1 242 ASN n 
1 243 VAL n 
1 244 SER n 
1 245 ALA n 
1 246 HIS n 
1 247 THR n 
1 248 ASN n 
1 249 LEU n 
1 250 LEU n 
1 251 VAL n 
1 252 ASN n 
1 253 SER n 
1 254 ALA n 
1 255 TYR n 
1 256 SER n 
1 257 ASP n 
1 258 ILE n 
1 259 TYR n 
1 260 ARG n 
1 261 SER n 
1 262 PHE n 
1 263 SER n 
1 264 ALA n 
1 265 ALA n 
1 266 MET n 
1 267 ASN n 
1 268 GLY n 
1 269 LEU n 
1 270 ALA n 
1 271 GLY n 
1 272 PRO n 
1 273 LEU n 
1 274 HIS n 
1 275 GLY n 
1 276 LEU n 
1 277 ALA n 
1 278 ASN n 
1 279 GLN n 
1 280 GLU n 
1 281 VAL n 
1 282 LEU n 
1 283 ARG n 
1 284 TRP n 
1 285 ILE n 
1 286 GLN n 
1 287 MET n 
1 288 LEU n 
1 289 TYR n 
1 290 LYS n 
1 291 LYS n 
1 292 PHE n 
1 293 GLY n 
1 294 GLY n 
1 295 VAL n 
1 296 PRO n 
1 297 THR n 
1 298 LYS n 
1 299 GLU n 
1 300 GLN n 
1 301 LEU n 
1 302 GLU n 
1 303 ARG n 
1 304 PHE n 
1 305 ALA n 
1 306 TRP n 
1 307 ASP n 
1 308 THR n 
1 309 LEU n 
1 310 ASN n 
1 311 SER n 
1 312 GLY n 
1 313 GLN n 
1 314 VAL n 
1 315 ILE n 
1 316 PRO n 
1 317 GLY n 
1 318 TYR n 
1 319 GLY n 
1 320 HIS n 
1 321 ALA n 
1 322 VAL n 
1 323 LEU n 
1 324 ARG n 
1 325 VAL n 
1 326 THR n 
1 327 ASP n 
1 328 PRO n 
1 329 ARG n 
1 330 TYR n 
1 331 VAL n 
1 332 ALA n 
1 333 GLN n 
1 334 ARG n 
1 335 ASP n 
1 336 PHE n 
1 337 ALA n 
1 338 LEU n 
1 339 LYS n 
1 340 HIS n 
1 341 LEU n 
1 342 PRO n 
1 343 ASP n 
1 344 ASP n 
1 345 GLU n 
1 346 LEU n 
1 347 PHE n 
1 348 LYS n 
1 349 ILE n 
1 350 VAL n 
1 351 SER n 
1 352 LEU n 
1 353 CYS n 
1 354 TYR n 
1 355 GLU n 
1 356 VAL n 
1 357 ILE n 
1 358 PRO n 
1 359 GLU n 
1 360 VAL n 
1 361 LEU n 
1 362 LYS n 
1 363 LYS n 
1 364 HIS n 
1 365 GLY n 
1 366 LYS n 
1 367 ALA n 
1 368 LYS n 
1 369 ASN n 
1 370 PRO n 
1 371 TRP n 
1 372 PRO n 
1 373 ASN n 
1 374 VAL n 
1 375 ASP n 
1 376 ALA n 
1 377 HIS n 
1 378 SER n 
1 379 GLY n 
1 380 VAL n 
1 381 LEU n 
1 382 LEU n 
1 383 TRP n 
1 384 HIS n 
1 385 TYR n 
1 386 GLY n 
1 387 ILE n 
1 388 ARG n 
1 389 GLU n 
1 390 TYR n 
1 391 ASP n 
1 392 PHE n 
1 393 TYR n 
1 394 THR n 
1 395 VAL n 
1 396 LEU n 
1 397 PHE n 
1 398 GLY n 
1 399 VAL n 
1 400 SER n 
1 401 ARG n 
1 402 ALA n 
1 403 LEU n 
1 404 GLY n 
1 405 CYS n 
1 406 THR n 
1 407 ALA n 
1 408 GLN n 
1 409 ALA n 
1 410 ILE n 
1 411 LEU n 
1 412 VAL n 
1 413 ARG n 
1 414 GLY n 
1 415 TYR n 
1 416 MET n 
1 417 LEU n 
1 418 PRO n 
1 419 ILE n 
1 420 GLU n 
1 421 ARG n 
1 422 PRO n 
1 423 LYS n 
1 424 SER n 
1 425 ILE n 
1 426 THR n 
1 427 THR n 
1 428 ARG n 
1 429 TRP n 
1 430 VAL n 
1 431 LYS n 
1 432 GLU n 
1 433 VAL n 
1 434 ALA n 
1 435 GLU n 
1 436 SER n 
1 437 LEU n 
1 438 PRO n 
1 439 VAL n 
1 440 ALA n 
1 441 GLY n 
1 442 SER n 
1 443 LYS n 
1 444 LEU n 
1 445 ALA n 
1 446 ALA n 
1 447 ALA n 
1 448 LEU n 
1 449 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   449 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'gltA, TST_0783' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Thermosulfidibacter takaii' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     412593 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ACO non-polymer         . 'ACETYL COENZYME *A' ? 'C23 H38 N7 O17 P3 S' 809.571 
ALA 'L-peptide linking' y ALANINE              ? 'C3 H7 N O2'          89.093  
ARG 'L-peptide linking' y ARGININE             ? 'C6 H15 N4 O2 1'      175.209 
ASN 'L-peptide linking' y ASPARAGINE           ? 'C4 H8 N2 O3'         132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'      ? 'C4 H7 N O4'          133.103 
COA non-polymer         . 'COENZYME A'         ? 'C21 H36 N7 O16 P3 S' 767.534 
CYS 'L-peptide linking' y CYSTEINE             ? 'C3 H7 N O2 S'        121.158 
GLN 'L-peptide linking' y GLUTAMINE            ? 'C5 H10 N2 O3'        146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'      ? 'C5 H9 N O4'          147.129 
GLY 'peptide linking'   y GLYCINE              ? 'C2 H5 N O2'          75.067  
HIS 'L-peptide linking' y HISTIDINE            ? 'C6 H10 N3 O2 1'      156.162 
HOH non-polymer         . WATER                ? 'H2 O'                18.015  
ILE 'L-peptide linking' y ISOLEUCINE           ? 'C6 H13 N O2'         131.173 
LEU 'L-peptide linking' y LEUCINE              ? 'C6 H13 N O2'         131.173 
LYS 'L-peptide linking' y LYSINE               ? 'C6 H15 N2 O2 1'      147.195 
MET 'L-peptide linking' y METHIONINE           ? 'C5 H11 N O2 S'       149.211 
OAA non-polymer         . 'OXALOACETATE ION'   ? 'C4 H3 O5 -1'         131.064 
PHE 'L-peptide linking' y PHENYLALANINE        ? 'C9 H11 N O2'         165.189 
PRO 'L-peptide linking' y PROLINE              ? 'C5 H9 N O2'          115.130 
SER 'L-peptide linking' y SERINE               ? 'C3 H7 N O3'          105.093 
THR 'L-peptide linking' y THREONINE            ? 'C4 H9 N O3'          119.119 
TRP 'L-peptide linking' y TRYPTOPHAN           ? 'C11 H12 N2 O2'       204.225 
TYR 'L-peptide linking' y TYROSINE             ? 'C9 H11 N O3'         181.189 
VAL 'L-peptide linking' y VALINE               ? 'C5 H11 N O2'         117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   LYS 4   4   4   LYS LYS A . n 
A 1 5   GLU 5   5   5   GLU GLU A . n 
A 1 6   ARG 6   6   6   ARG ARG A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   ALA 8   8   8   ALA ALA A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  ILE 11  11  11  ILE ILE A . n 
A 1 12  PRO 12  12  12  PRO PRO A . n 
A 1 13  GLN 13  13  13  GLN GLN A . n 
A 1 14  TRP 14  14  14  TRP TRP A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  GLU 20  20  20  GLU GLU A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  LYS 23  23  23  LYS LYS A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  TYR 25  25  25  TYR TYR A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  ASN 27  27  27  ASN ASN A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  CYS 33  33  33  CYS CYS A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  ILE 35  35  35  ILE ILE A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  HIS 37  37  37  HIS HIS A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  MET 42  42  42  MET MET A . n 
A 1 43  ARG 43  43  43  ARG ARG A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  VAL 49  49  49  VAL VAL A . n 
A 1 50  CYS 50  50  50  CYS CYS A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  THR 52  52  52  THR THR A . n 
A 1 53  SER 53  53  53  SER SER A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PHE 63  63  63  PHE PHE A . n 
A 1 64  ARG 64  64  64  ARG ARG A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  TYR 66  66  66  TYR TYR A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  PRO 69  69  69  PRO PRO A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  PRO 75  75  75  PRO PRO A . n 
A 1 76  HIS 76  76  76  HIS HIS A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  GLU 82  82  82  GLU GLU A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  PHE 85  85  85  PHE PHE A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  TRP 93  93  93  TRP TRP A . n 
A 1 94  TYR 94  94  94  TYR TYR A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 GLU 105 105 105 GLU GLU A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 VAL 107 107 107 VAL VAL A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 ILE 110 110 110 ILE ILE A . n 
A 1 111 SER 111 111 111 SER SER A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 GLN 119 119 119 GLN GLN A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 VAL 121 121 121 VAL VAL A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 PHE 126 126 126 PHE PHE A . n 
A 1 127 ASP 127 127 127 ASP ASP A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 ARG 130 130 130 ARG ARG A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 HIS 137 137 137 HIS HIS A . n 
A 1 138 PRO 138 138 138 PRO PRO A . n 
A 1 139 MET 139 139 139 MET MET A . n 
A 1 140 THR 140 140 140 THR THR A . n 
A 1 141 MET 141 141 141 MET MET A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 MET 149 149 149 MET MET A . n 
A 1 150 GLN 150 150 150 GLN GLN A . n 
A 1 151 ARG 151 151 151 ARG ARG A . n 
A 1 152 GLU 152 152 152 GLU GLU A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 VAL 154 154 154 VAL VAL A . n 
A 1 155 PHE 155 155 155 PHE PHE A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 LYS 157 157 157 LYS LYS A . n 
A 1 158 ARG 158 158 158 ARG ARG A . n 
A 1 159 TYR 159 159 159 TYR TYR A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 GLU 161 161 161 GLU GLU A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 MET 163 163 163 MET MET A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 ARG 165 165 165 ARG ARG A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 GLU 167 167 167 GLU GLU A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 TRP 169 169 169 TRP TRP A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 ASP 175 175 175 ASP ASP A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 LEU 183 183 183 LEU LEU A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 TYR 189 189 189 TYR TYR A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 TYR 191 191 191 TYR TYR A . n 
A 1 192 ARG 192 192 192 ARG ARG A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 LYS 194 194 194 LYS LYS A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 GLY 197 197 197 GLY GLY A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 HIS 200 200 200 HIS HIS A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 PRO 203 203 203 PRO PRO A . n 
A 1 204 ASP 204 204 204 ASP ASP A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 ASN 206 206 206 ASN ASN A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 ASP 208 208 208 ASP ASP A . n 
A 1 209 TRP 209 209 209 TRP TRP A . n 
A 1 210 SER 210 210 210 SER SER A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 ASN 212 212 212 ASN ASN A . n 
A 1 213 LEU 213 213 213 LEU LEU A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 HIS 215 215 215 HIS HIS A . n 
A 1 216 MET 216 216 216 MET MET A . n 
A 1 217 MET 217 217 217 MET MET A . n 
A 1 218 GLY 218 218 218 GLY GLY A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 ASP 220 220 220 ASP ASP A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 PHE 222 222 222 PHE PHE A . n 
A 1 223 GLU 223 223 223 GLU GLU A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 TYR 225 225 225 TYR TYR A . n 
A 1 226 GLU 226 226 226 GLU GLU A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 PHE 228 228 228 PHE PHE A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 TYR 231 231 231 TYR TYR A . n 
A 1 232 MET 232 232 232 MET MET A . n 
A 1 233 PHE 233 233 233 PHE PHE A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 HIS 235 235 235 HIS HIS A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 HIS 238 238 238 HIS HIS A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 ASN 242 242 242 ASN ASN A . n 
A 1 243 VAL 243 243 243 VAL VAL A . n 
A 1 244 SER 244 244 244 SER SER A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 ASP 257 257 257 ASP ASP A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 TYR 259 259 259 TYR TYR A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 PHE 262 262 262 PHE PHE A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 MET 266 266 266 MET MET A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 PRO 272 272 272 PRO PRO A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 HIS 274 274 274 HIS HIS A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 GLN 279 279 279 GLN GLN A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 VAL 281 281 281 VAL VAL A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 ARG 283 283 283 ARG ARG A . n 
A 1 284 TRP 284 284 284 TRP TRP A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 GLN 286 286 286 GLN GLN A . n 
A 1 287 MET 287 287 287 MET MET A . n 
A 1 288 LEU 288 288 288 LEU LEU A . n 
A 1 289 TYR 289 289 289 TYR TYR A . n 
A 1 290 LYS 290 290 290 LYS LYS A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 PHE 292 292 292 PHE PHE A . n 
A 1 293 GLY 293 293 293 GLY GLY A . n 
A 1 294 GLY 294 294 294 GLY GLY A . n 
A 1 295 VAL 295 295 295 VAL VAL A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 GLN 300 300 300 GLN GLN A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 GLU 302 302 302 GLU GLU A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 PHE 304 304 304 PHE PHE A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 TRP 306 306 306 TRP TRP A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 THR 308 308 308 THR THR A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 TYR 318 318 318 TYR TYR A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 HIS 320 320 320 HIS HIS A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 ARG 324 324 324 ARG ARG A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 THR 326 326 326 THR THR A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 PRO 328 328 328 PRO PRO A . n 
A 1 329 ARG 329 329 329 ARG ARG A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 VAL 331 331 331 VAL VAL A . n 
A 1 332 ALA 332 332 332 ALA ALA A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 LYS 339 339 339 LYS LYS A . n 
A 1 340 HIS 340 340 340 HIS HIS A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 GLU 345 345 345 GLU GLU A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 LYS 348 348 348 LYS LYS A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 CYS 353 353 353 CYS CYS A . n 
A 1 354 TYR 354 354 354 TYR TYR A . n 
A 1 355 GLU 355 355 355 GLU GLU A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 GLU 359 359 359 GLU GLU A . n 
A 1 360 VAL 360 360 360 VAL VAL A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 LYS 362 362 362 LYS LYS A . n 
A 1 363 LYS 363 363 363 LYS LYS A . n 
A 1 364 HIS 364 364 364 HIS HIS A . n 
A 1 365 GLY 365 365 ?   ?   ?   A . n 
A 1 366 LYS 366 366 ?   ?   ?   A . n 
A 1 367 ALA 367 367 ?   ?   ?   A . n 
A 1 368 LYS 368 368 ?   ?   ?   A . n 
A 1 369 ASN 369 369 ?   ?   ?   A . n 
A 1 370 PRO 370 370 370 PRO PRO A . n 
A 1 371 TRP 371 371 371 TRP TRP A . n 
A 1 372 PRO 372 372 372 PRO PRO A . n 
A 1 373 ASN 373 373 373 ASN ASN A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 ASP 375 375 375 ASP ASP A . n 
A 1 376 ALA 376 376 376 ALA ALA A . n 
A 1 377 HIS 377 377 377 HIS HIS A . n 
A 1 378 SER 378 378 378 SER SER A . n 
A 1 379 GLY 379 379 379 GLY GLY A . n 
A 1 380 VAL 380 380 380 VAL VAL A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 TRP 383 383 383 TRP TRP A . n 
A 1 384 HIS 384 384 384 HIS HIS A . n 
A 1 385 TYR 385 385 385 TYR TYR A . n 
A 1 386 GLY 386 386 386 GLY GLY A . n 
A 1 387 ILE 387 387 387 ILE ILE A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 GLU 389 389 389 GLU GLU A . n 
A 1 390 TYR 390 390 390 TYR TYR A . n 
A 1 391 ASP 391 391 391 ASP ASP A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 TYR 393 393 393 TYR TYR A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 VAL 395 395 395 VAL VAL A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 GLY 398 398 398 GLY GLY A . n 
A 1 399 VAL 399 399 399 VAL VAL A . n 
A 1 400 SER 400 400 400 SER SER A . n 
A 1 401 ARG 401 401 401 ARG ARG A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 GLY 404 404 404 GLY GLY A . n 
A 1 405 CYS 405 405 405 CYS CYS A . n 
A 1 406 THR 406 406 406 THR THR A . n 
A 1 407 ALA 407 407 407 ALA ALA A . n 
A 1 408 GLN 408 408 408 GLN GLN A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 ILE 410 410 410 ILE ILE A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ARG 413 413 413 ARG ARG A . n 
A 1 414 GLY 414 414 414 GLY GLY A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 MET 416 416 416 MET MET A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 PRO 418 418 418 PRO PRO A . n 
A 1 419 ILE 419 419 419 ILE ILE A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 PRO 422 422 422 PRO PRO A . n 
A 1 423 LYS 423 423 423 LYS LYS A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 THR 427 427 427 THR THR A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 TRP 429 429 429 TRP TRP A . n 
A 1 430 VAL 430 430 430 VAL VAL A . n 
A 1 431 LYS 431 431 431 LYS LYS A . n 
A 1 432 GLU 432 432 432 GLU GLU A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 GLU 435 435 435 GLU GLU A . n 
A 1 436 SER 436 436 436 SER SER A . n 
A 1 437 LEU 437 437 437 LEU LEU A . n 
A 1 438 PRO 438 438 438 PRO PRO A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 ALA 440 440 440 ALA ALA A . n 
A 1 441 GLY 441 441 ?   ?   ?   A . n 
A 1 442 SER 442 442 ?   ?   ?   A . n 
A 1 443 LYS 443 443 ?   ?   ?   A . n 
A 1 444 LEU 444 444 ?   ?   ?   A . n 
A 1 445 ALA 445 445 ?   ?   ?   A . n 
A 1 446 ALA 446 446 ?   ?   ?   A . n 
A 1 447 ALA 447 447 ?   ?   ?   A . n 
A 1 448 LEU 448 448 ?   ?   ?   A . n 
A 1 449 GLU 449 449 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   LYS 2   2   2   LYS LYS B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   LYS 4   4   4   LYS LYS B . n 
B 1 5   GLU 5   5   5   GLU GLU B . n 
B 1 6   ARG 6   6   6   ARG ARG B . n 
B 1 7   LEU 7   7   7   LEU LEU B . n 
B 1 8   ALA 8   8   8   ALA ALA B . n 
B 1 9   GLU 9   9   9   GLU GLU B . n 
B 1 10  LEU 10  10  10  LEU LEU B . n 
B 1 11  ILE 11  11  11  ILE ILE B . n 
B 1 12  PRO 12  12  12  PRO PRO B . n 
B 1 13  GLN 13  13  13  GLN GLN B . n 
B 1 14  TRP 14  14  14  TRP TRP B . n 
B 1 15  ARG 15  15  15  ARG ARG B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  GLU 17  17  17  GLU GLU B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  GLU 20  20  20  GLU GLU B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  ARG 22  22  22  ARG ARG B . n 
B 1 23  LYS 23  23  23  LYS LYS B . n 
B 1 24  LYS 24  24  24  LYS LYS B . n 
B 1 25  TYR 25  25  25  TYR TYR B . n 
B 1 26  GLY 26  26  26  GLY GLY B . n 
B 1 27  ASN 27  27  27  ASN ASN B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  THR 30  30  30  THR THR B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  ASP 32  32  32  ASP ASP B . n 
B 1 33  CYS 33  33  33  CYS CYS B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  ILE 35  35  35  ILE ILE B . n 
B 1 36  GLY 36  36  36  GLY GLY B . n 
B 1 37  HIS 37  37  37  HIS HIS B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  GLY 40  40  40  GLY GLY B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  MET 42  42  42  MET MET B . n 
B 1 43  ARG 43  43  43  ARG ARG B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  LYS 46  46  46  LYS LYS B . n 
B 1 47  ALA 47  47  47  ALA ALA B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  VAL 49  49  49  VAL VAL B . n 
B 1 50  CYS 50  50  50  CYS CYS B . n 
B 1 51  ASP 51  51  51  ASP ASP B . n 
B 1 52  THR 52  52  52  THR THR B . n 
B 1 53  SER 53  53  53  SER SER B . n 
B 1 54  GLU 54  54  54  GLU GLU B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  PHE 56  56  56  PHE PHE B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  VAL 61  61  61  VAL VAL B . n 
B 1 62  LYS 62  62  62  LYS LYS B . n 
B 1 63  PHE 63  63  63  PHE PHE B . n 
B 1 64  ARG 64  64  64  ARG ARG B . n 
B 1 65  GLY 65  65  65  GLY GLY B . n 
B 1 66  TYR 66  66  66  TYR TYR B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  ILE 68  68  68  ILE ILE B . n 
B 1 69  PRO 69  69  69  PRO PRO B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  GLU 73  73  73  GLU GLU B . n 
B 1 74  GLY 74  74  74  GLY GLY B . n 
B 1 75  PRO 75  75  75  PRO PRO B . n 
B 1 76  HIS 76  76  76  HIS HIS B . n 
B 1 77  LYS 77  77  77  LYS LYS B . n 
B 1 78  LEU 78  78  78  LEU LEU B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  THR 80  80  80  THR THR B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  GLU 82  82  82  GLU GLU B . n 
B 1 83  GLY 83  83  83  GLY GLY B . n 
B 1 84  GLY 84  84  84  GLY GLY B . n 
B 1 85  PHE 85  85  85  PHE PHE B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  LEU 92  92  92  LEU LEU B . n 
B 1 93  TRP 93  93  93  TRP TRP B . n 
B 1 94  TYR 94  94  94  TYR TYR B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  GLY 99  99  99  GLY GLY B . n 
B 1 100 GLU 100 100 100 GLU GLU B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 PRO 102 102 102 PRO PRO B . n 
B 1 103 THR 103 103 103 THR THR B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 GLU 105 105 105 GLU GLU B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 VAL 107 107 107 VAL VAL B . n 
B 1 108 LYS 108 108 108 LYS LYS B . n 
B 1 109 GLU 109 109 109 GLU GLU B . n 
B 1 110 ILE 110 110 110 ILE ILE B . n 
B 1 111 SER 111 111 111 SER SER B . n 
B 1 112 ALA 112 112 112 ALA ALA B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 THR 115 115 115 THR THR B . n 
B 1 116 LYS 116 116 116 LYS LYS B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 MET 118 118 118 MET MET B . n 
B 1 119 GLN 119 119 119 GLN GLN B . n 
B 1 120 ASN 120 120 120 ASN ASN B . n 
B 1 121 VAL 121 121 121 VAL VAL B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 GLN 123 123 123 GLN GLN B . n 
B 1 124 TYR 124 124 124 TYR TYR B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 PHE 126 126 126 PHE PHE B . n 
B 1 127 ASP 127 127 127 ASP ASP B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 ARG 130 130 130 ARG ARG B . n 
B 1 131 ALA 131 131 131 ALA ALA B . n 
B 1 132 MET 132 132 132 MET MET B . n 
B 1 133 PRO 133 133 133 PRO PRO B . n 
B 1 134 VAL 134 134 134 VAL VAL B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 THR 136 136 136 THR THR B . n 
B 1 137 HIS 137 137 137 HIS HIS B . n 
B 1 138 PRO 138 138 138 PRO PRO B . n 
B 1 139 MET 139 139 139 MET MET B . n 
B 1 140 THR 140 140 140 THR THR B . n 
B 1 141 MET 141 141 141 MET MET B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ALA 143 143 143 ALA ALA B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 MET 149 149 149 MET MET B . n 
B 1 150 GLN 150 150 150 GLN GLN B . n 
B 1 151 ARG 151 151 151 ARG ARG B . n 
B 1 152 GLU 152 152 152 GLU GLU B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 VAL 154 154 154 VAL VAL B . n 
B 1 155 PHE 155 155 155 PHE PHE B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 LYS 157 157 157 LYS LYS B . n 
B 1 158 ARG 158 158 158 ARG ARG B . n 
B 1 159 TYR 159 159 159 TYR TYR B . n 
B 1 160 GLU 160 160 160 GLU GLU B . n 
B 1 161 GLU 161 161 161 GLU GLU B . n 
B 1 162 GLY 162 162 162 GLY GLY B . n 
B 1 163 MET 163 163 163 MET MET B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 ARG 165 165 165 ARG ARG B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 GLU 167 167 167 GLU GLU B . n 
B 1 168 HIS 168 168 168 HIS HIS B . n 
B 1 169 TRP 169 169 169 TRP TRP B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 MET 172 172 172 MET MET B . n 
B 1 173 LEU 173 173 173 LEU LEU B . n 
B 1 174 GLU 174 174 174 GLU GLU B . n 
B 1 175 ASP 175 175 175 ASP ASP B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 ASN 178 178 178 ASN ASN B . n 
B 1 179 MET 179 179 179 MET MET B . n 
B 1 180 LEU 180 180 180 LEU LEU B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 LEU 183 183 183 LEU LEU B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 VAL 185 185 185 VAL VAL B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 TYR 189 189 189 TYR TYR B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 TYR 191 191 191 TYR TYR B . n 
B 1 192 ARG 192 192 192 ARG ARG B . n 
B 1 193 ARG 193 193 193 ARG ARG B . n 
B 1 194 LYS 194 194 194 LYS LYS B . n 
B 1 195 TYR 195 195 195 TYR TYR B . n 
B 1 196 LYS 196 196 196 LYS LYS B . n 
B 1 197 GLY 197 197 197 GLY GLY B . n 
B 1 198 ASP 198 198 198 ASP ASP B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 HIS 200 200 200 HIS HIS B . n 
B 1 201 ILE 201 201 201 ILE ILE B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 PRO 203 203 203 PRO PRO B . n 
B 1 204 ASP 204 204 204 ASP ASP B . n 
B 1 205 PRO 205 205 205 PRO PRO B . n 
B 1 206 ASN 206 206 206 ASN ASN B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 ASP 208 208 208 ASP ASP B . n 
B 1 209 TRP 209 209 209 TRP TRP B . n 
B 1 210 SER 210 210 210 SER SER B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 ASN 212 212 212 ASN ASN B . n 
B 1 213 LEU 213 213 213 LEU LEU B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 HIS 215 215 215 HIS HIS B . n 
B 1 216 MET 216 216 216 MET MET B . n 
B 1 217 MET 217 217 217 MET MET B . n 
B 1 218 GLY 218 218 218 GLY GLY B . n 
B 1 219 PHE 219 219 219 PHE PHE B . n 
B 1 220 ASP 220 220 220 ASP ASP B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 PHE 222 222 222 PHE PHE B . n 
B 1 223 GLU 223 223 223 GLU GLU B . n 
B 1 224 VAL 224 224 224 VAL VAL B . n 
B 1 225 TYR 225 225 225 TYR TYR B . n 
B 1 226 GLU 226 226 226 GLU GLU B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 PHE 228 228 228 PHE PHE B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 TYR 231 231 231 TYR TYR B . n 
B 1 232 MET 232 232 232 MET MET B . n 
B 1 233 PHE 233 233 233 PHE PHE B . n 
B 1 234 LEU 234 234 234 LEU LEU B . n 
B 1 235 HIS 235 235 235 HIS HIS B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 ASP 237 237 237 ASP ASP B . n 
B 1 238 HIS 238 238 238 HIS HIS B . n 
B 1 239 GLU 239 239 239 GLU GLU B . n 
B 1 240 GLY 240 240 240 GLY GLY B . n 
B 1 241 GLY 241 241 241 GLY GLY B . n 
B 1 242 ASN 242 242 242 ASN ASN B . n 
B 1 243 VAL 243 243 243 VAL VAL B . n 
B 1 244 SER 244 244 244 SER SER B . n 
B 1 245 ALA 245 245 245 ALA ALA B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 THR 247 247 247 THR THR B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 VAL 251 251 251 VAL VAL B . n 
B 1 252 ASN 252 252 252 ASN ASN B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 TYR 255 255 255 TYR TYR B . n 
B 1 256 SER 256 256 256 SER SER B . n 
B 1 257 ASP 257 257 257 ASP ASP B . n 
B 1 258 ILE 258 258 258 ILE ILE B . n 
B 1 259 TYR 259 259 259 TYR TYR B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 PHE 262 262 262 PHE PHE B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 MET 266 266 266 MET MET B . n 
B 1 267 ASN 267 267 267 ASN ASN B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 LEU 269 269 269 LEU LEU B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 GLY 271 271 271 GLY GLY B . n 
B 1 272 PRO 272 272 272 PRO PRO B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 HIS 274 274 274 HIS HIS B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 LEU 276 276 276 LEU LEU B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 ASN 278 278 278 ASN ASN B . n 
B 1 279 GLN 279 279 279 GLN GLN B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 VAL 281 281 281 VAL VAL B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 ARG 283 283 283 ARG ARG B . n 
B 1 284 TRP 284 284 284 TRP TRP B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 GLN 286 286 286 GLN GLN B . n 
B 1 287 MET 287 287 287 MET MET B . n 
B 1 288 LEU 288 288 288 LEU LEU B . n 
B 1 289 TYR 289 289 289 TYR TYR B . n 
B 1 290 LYS 290 290 290 LYS LYS B . n 
B 1 291 LYS 291 291 291 LYS LYS B . n 
B 1 292 PHE 292 292 292 PHE PHE B . n 
B 1 293 GLY 293 293 293 GLY GLY B . n 
B 1 294 GLY 294 294 294 GLY GLY B . n 
B 1 295 VAL 295 295 295 VAL VAL B . n 
B 1 296 PRO 296 296 296 PRO PRO B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 LYS 298 298 298 LYS LYS B . n 
B 1 299 GLU 299 299 299 GLU GLU B . n 
B 1 300 GLN 300 300 300 GLN GLN B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 GLU 302 302 302 GLU GLU B . n 
B 1 303 ARG 303 303 303 ARG ARG B . n 
B 1 304 PHE 304 304 304 PHE PHE B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 TRP 306 306 306 TRP TRP B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 THR 308 308 308 THR THR B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 GLY 312 312 312 GLY GLY B . n 
B 1 313 GLN 313 313 313 GLN GLN B . n 
B 1 314 VAL 314 314 314 VAL VAL B . n 
B 1 315 ILE 315 315 315 ILE ILE B . n 
B 1 316 PRO 316 316 316 PRO PRO B . n 
B 1 317 GLY 317 317 317 GLY GLY B . n 
B 1 318 TYR 318 318 318 TYR TYR B . n 
B 1 319 GLY 319 319 319 GLY GLY B . n 
B 1 320 HIS 320 320 320 HIS HIS B . n 
B 1 321 ALA 321 321 321 ALA ALA B . n 
B 1 322 VAL 322 322 322 VAL VAL B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 ARG 324 324 324 ARG ARG B . n 
B 1 325 VAL 325 325 325 VAL VAL B . n 
B 1 326 THR 326 326 326 THR THR B . n 
B 1 327 ASP 327 327 327 ASP ASP B . n 
B 1 328 PRO 328 328 328 PRO PRO B . n 
B 1 329 ARG 329 329 329 ARG ARG B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 VAL 331 331 331 VAL VAL B . n 
B 1 332 ALA 332 332 332 ALA ALA B . n 
B 1 333 GLN 333 333 333 GLN GLN B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 ASP 335 335 335 ASP ASP B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 LEU 338 338 338 LEU LEU B . n 
B 1 339 LYS 339 339 339 LYS LYS B . n 
B 1 340 HIS 340 340 340 HIS HIS B . n 
B 1 341 LEU 341 341 341 LEU LEU B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 GLU 345 345 345 GLU GLU B . n 
B 1 346 LEU 346 346 346 LEU LEU B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 LYS 348 348 348 LYS LYS B . n 
B 1 349 ILE 349 349 349 ILE ILE B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 SER 351 351 351 SER SER B . n 
B 1 352 LEU 352 352 352 LEU LEU B . n 
B 1 353 CYS 353 353 353 CYS CYS B . n 
B 1 354 TYR 354 354 354 TYR TYR B . n 
B 1 355 GLU 355 355 355 GLU GLU B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 ILE 357 357 357 ILE ILE B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 GLU 359 359 359 GLU GLU B . n 
B 1 360 VAL 360 360 360 VAL VAL B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 LYS 362 362 362 LYS LYS B . n 
B 1 363 LYS 363 363 363 LYS LYS B . n 
B 1 364 HIS 364 364 364 HIS HIS B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 LYS 366 366 366 LYS LYS B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 LYS 368 368 368 LYS LYS B . n 
B 1 369 ASN 369 369 369 ASN ASN B . n 
B 1 370 PRO 370 370 370 PRO PRO B . n 
B 1 371 TRP 371 371 371 TRP TRP B . n 
B 1 372 PRO 372 372 372 PRO PRO B . n 
B 1 373 ASN 373 373 373 ASN ASN B . n 
B 1 374 VAL 374 374 374 VAL VAL B . n 
B 1 375 ASP 375 375 375 ASP ASP B . n 
B 1 376 ALA 376 376 376 ALA ALA B . n 
B 1 377 HIS 377 377 377 HIS HIS B . n 
B 1 378 SER 378 378 378 SER SER B . n 
B 1 379 GLY 379 379 379 GLY GLY B . n 
B 1 380 VAL 380 380 380 VAL VAL B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 TRP 383 383 383 TRP TRP B . n 
B 1 384 HIS 384 384 384 HIS HIS B . n 
B 1 385 TYR 385 385 385 TYR TYR B . n 
B 1 386 GLY 386 386 386 GLY GLY B . n 
B 1 387 ILE 387 387 387 ILE ILE B . n 
B 1 388 ARG 388 388 388 ARG ARG B . n 
B 1 389 GLU 389 389 389 GLU GLU B . n 
B 1 390 TYR 390 390 390 TYR TYR B . n 
B 1 391 ASP 391 391 391 ASP ASP B . n 
B 1 392 PHE 392 392 392 PHE PHE B . n 
B 1 393 TYR 393 393 393 TYR TYR B . n 
B 1 394 THR 394 394 394 THR THR B . n 
B 1 395 VAL 395 395 395 VAL VAL B . n 
B 1 396 LEU 396 396 396 LEU LEU B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 GLY 398 398 398 GLY GLY B . n 
B 1 399 VAL 399 399 399 VAL VAL B . n 
B 1 400 SER 400 400 400 SER SER B . n 
B 1 401 ARG 401 401 401 ARG ARG B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 GLY 404 404 404 GLY GLY B . n 
B 1 405 CYS 405 405 405 CYS CYS B . n 
B 1 406 THR 406 406 406 THR THR B . n 
B 1 407 ALA 407 407 407 ALA ALA B . n 
B 1 408 GLN 408 408 408 GLN GLN B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 ILE 410 410 410 ILE ILE B . n 
B 1 411 LEU 411 411 411 LEU LEU B . n 
B 1 412 VAL 412 412 412 VAL VAL B . n 
B 1 413 ARG 413 413 413 ARG ARG B . n 
B 1 414 GLY 414 414 414 GLY GLY B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 MET 416 416 416 MET MET B . n 
B 1 417 LEU 417 417 417 LEU LEU B . n 
B 1 418 PRO 418 418 418 PRO PRO B . n 
B 1 419 ILE 419 419 419 ILE ILE B . n 
B 1 420 GLU 420 420 420 GLU GLU B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 PRO 422 422 422 PRO PRO B . n 
B 1 423 LYS 423 423 423 LYS LYS B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 THR 427 427 427 THR THR B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 TRP 429 429 429 TRP TRP B . n 
B 1 430 VAL 430 430 430 VAL VAL B . n 
B 1 431 LYS 431 431 431 LYS LYS B . n 
B 1 432 GLU 432 432 432 GLU GLU B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 GLU 435 435 435 GLU GLU B . n 
B 1 436 SER 436 436 436 SER SER B . n 
B 1 437 LEU 437 437 437 LEU LEU B . n 
B 1 438 PRO 438 438 438 PRO PRO B . n 
B 1 439 VAL 439 439 439 VAL VAL B . n 
B 1 440 ALA 440 440 440 ALA ALA B . n 
B 1 441 GLY 441 441 441 GLY GLY B . n 
B 1 442 SER 442 442 442 SER SER B . n 
B 1 443 LYS 443 443 443 LYS LYS B . n 
B 1 444 LEU 444 444 444 LEU LEU B . n 
B 1 445 ALA 445 445 445 ALA ALA B . n 
B 1 446 ALA 446 446 446 ALA ALA B . n 
B 1 447 ALA 447 447 447 ALA ALA B . n 
B 1 448 LEU 448 448 448 LEU LEU B . n 
B 1 449 GLU 449 449 449 GLU GLU B . n 
C 1 1   MET 1   1   1   MET MET C . n 
C 1 2   LYS 2   2   2   LYS LYS C . n 
C 1 3   LEU 3   3   3   LEU LEU C . n 
C 1 4   LYS 4   4   4   LYS LYS C . n 
C 1 5   GLU 5   5   5   GLU GLU C . n 
C 1 6   ARG 6   6   6   ARG ARG C . n 
C 1 7   LEU 7   7   7   LEU LEU C . n 
C 1 8   ALA 8   8   8   ALA ALA C . n 
C 1 9   GLU 9   9   9   GLU GLU C . n 
C 1 10  LEU 10  10  10  LEU LEU C . n 
C 1 11  ILE 11  11  11  ILE ILE C . n 
C 1 12  PRO 12  12  12  PRO PRO C . n 
C 1 13  GLN 13  13  13  GLN GLN C . n 
C 1 14  TRP 14  14  14  TRP TRP C . n 
C 1 15  ARG 15  15  15  ARG ARG C . n 
C 1 16  ALA 16  16  16  ALA ALA C . n 
C 1 17  GLU 17  17  17  GLU GLU C . n 
C 1 18  VAL 18  18  18  VAL VAL C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  GLU 20  20  20  GLU GLU C . n 
C 1 21  ILE 21  21  21  ILE ILE C . n 
C 1 22  ARG 22  22  22  ARG ARG C . n 
C 1 23  LYS 23  23  23  LYS LYS C . n 
C 1 24  LYS 24  24  24  LYS LYS C . n 
C 1 25  TYR 25  25  25  TYR TYR C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  ASN 27  27  27  ASN ASN C . n 
C 1 28  ARG 28  28  28  ARG ARG C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  THR 30  30  30  THR THR C . n 
C 1 31  MET 31  31  31  MET MET C . n 
C 1 32  ASP 32  32  32  ASP ASP C . n 
C 1 33  CYS 33  33  33  CYS CYS C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  ILE 35  35  35  ILE ILE C . n 
C 1 36  GLY 36  36  36  GLY GLY C . n 
C 1 37  HIS 37  37  37  HIS HIS C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  TYR 39  39  39  TYR TYR C . n 
C 1 40  GLY 40  40  40  GLY GLY C . n 
C 1 41  GLY 41  41  41  GLY GLY C . n 
C 1 42  MET 42  42  42  MET MET C . n 
C 1 43  ARG 43  43  43  ARG ARG C . n 
C 1 44  GLY 44  44  44  GLY GLY C . n 
C 1 45  LEU 45  45  45  LEU LEU C . n 
C 1 46  LYS 46  46  46  LYS LYS C . n 
C 1 47  ALA 47  47  47  ALA ALA C . n 
C 1 48  LEU 48  48  48  LEU LEU C . n 
C 1 49  VAL 49  49  49  VAL VAL C . n 
C 1 50  CYS 50  50  50  CYS CYS C . n 
C 1 51  ASP 51  51  51  ASP ASP C . n 
C 1 52  THR 52  52  52  THR THR C . n 
C 1 53  SER 53  53  53  SER SER C . n 
C 1 54  GLU 54  54  54  GLU GLU C . n 
C 1 55  VAL 55  55  55  VAL VAL C . n 
C 1 56  PHE 56  56  56  PHE PHE C . n 
C 1 57  PRO 57  57  57  PRO PRO C . n 
C 1 58  ASP 58  58  58  ASP ASP C . n 
C 1 59  GLU 59  59  59  GLU GLU C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  VAL 61  61  61  VAL VAL C . n 
C 1 62  LYS 62  62  62  LYS LYS C . n 
C 1 63  PHE 63  63  63  PHE PHE C . n 
C 1 64  ARG 64  64  64  ARG ARG C . n 
C 1 65  GLY 65  65  65  GLY GLY C . n 
C 1 66  TYR 66  66  66  TYR TYR C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  ILE 68  68  68  ILE ILE C . n 
C 1 69  PRO 69  69  69  PRO PRO C . n 
C 1 70  GLU 70  70  70  GLU GLU C . n 
C 1 71  LEU 71  71  71  LEU LEU C . n 
C 1 72  ARG 72  72  72  ARG ARG C . n 
C 1 73  GLU 73  73  73  GLU GLU C . n 
C 1 74  GLY 74  74  74  GLY GLY C . n 
C 1 75  PRO 75  75  75  PRO PRO C . n 
C 1 76  HIS 76  76  76  HIS HIS C . n 
C 1 77  LYS 77  77  77  LYS LYS C . n 
C 1 78  LEU 78  78  78  LEU LEU C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  THR 80  80  80  THR THR C . n 
C 1 81  ALA 81  81  81  ALA ALA C . n 
C 1 82  GLU 82  82  82  GLU GLU C . n 
C 1 83  GLY 83  83  83  GLY GLY C . n 
C 1 84  GLY 84  84  84  GLY GLY C . n 
C 1 85  PHE 85  85  85  PHE PHE C . n 
C 1 86  GLU 86  86  86  GLU GLU C . n 
C 1 87  PRO 87  87  87  PRO PRO C . n 
C 1 88  LEU 88  88  88  LEU LEU C . n 
C 1 89  PRO 89  89  89  PRO PRO C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  LEU 92  92  92  LEU LEU C . n 
C 1 93  TRP 93  93  93  TRP TRP C . n 
C 1 94  TYR 94  94  94  TYR TYR C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  LEU 96  96  96  LEU LEU C . n 
C 1 97  LEU 97  97  97  LEU LEU C . n 
C 1 98  THR 98  98  98  THR THR C . n 
C 1 99  GLY 99  99  99  GLY GLY C . n 
C 1 100 GLU 100 100 100 GLU GLU C . n 
C 1 101 LEU 101 101 101 LEU LEU C . n 
C 1 102 PRO 102 102 102 PRO PRO C . n 
C 1 103 THR 103 103 103 THR THR C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 GLU 105 105 105 GLU GLU C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 VAL 107 107 107 VAL VAL C . n 
C 1 108 LYS 108 108 108 LYS LYS C . n 
C 1 109 GLU 109 109 109 GLU GLU C . n 
C 1 110 ILE 110 110 110 ILE ILE C . n 
C 1 111 SER 111 111 111 SER SER C . n 
C 1 112 ALA 112 112 112 ALA ALA C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 PHE 114 114 114 PHE PHE C . n 
C 1 115 THR 115 115 115 THR THR C . n 
C 1 116 LYS 116 116 116 LYS LYS C . n 
C 1 117 ARG 117 117 117 ARG ARG C . n 
C 1 118 MET 118 118 118 MET MET C . n 
C 1 119 GLN 119 119 119 GLN GLN C . n 
C 1 120 ASN 120 120 120 ASN ASN C . n 
C 1 121 VAL 121 121 121 VAL VAL C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 GLN 123 123 123 GLN GLN C . n 
C 1 124 TYR 124 124 124 TYR TYR C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 PHE 126 126 126 PHE PHE C . n 
C 1 127 ASP 127 127 127 ASP ASP C . n 
C 1 128 VAL 128 128 128 VAL VAL C . n 
C 1 129 LEU 129 129 129 LEU LEU C . n 
C 1 130 ARG 130 130 130 ARG ARG C . n 
C 1 131 ALA 131 131 131 ALA ALA C . n 
C 1 132 MET 132 132 132 MET MET C . n 
C 1 133 PRO 133 133 133 PRO PRO C . n 
C 1 134 VAL 134 134 134 VAL VAL C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 THR 136 136 136 THR THR C . n 
C 1 137 HIS 137 137 137 HIS HIS C . n 
C 1 138 PRO 138 138 138 PRO PRO C . n 
C 1 139 MET 139 139 139 MET MET C . n 
C 1 140 THR 140 140 140 THR THR C . n 
C 1 141 MET 141 141 141 MET MET C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 ALA 143 143 143 ALA ALA C . n 
C 1 144 ALA 144 144 144 ALA ALA C . n 
C 1 145 GLY 145 145 145 GLY GLY C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 LEU 147 147 147 LEU LEU C . n 
C 1 148 ALA 148 148 148 ALA ALA C . n 
C 1 149 MET 149 149 149 MET MET C . n 
C 1 150 GLN 150 150 150 GLN GLN C . n 
C 1 151 ARG 151 151 151 ARG ARG C . n 
C 1 152 GLU 152 152 152 GLU GLU C . n 
C 1 153 SER 153 153 153 SER SER C . n 
C 1 154 VAL 154 154 154 VAL VAL C . n 
C 1 155 PHE 155 155 155 PHE PHE C . n 
C 1 156 ALA 156 156 156 ALA ALA C . n 
C 1 157 LYS 157 157 157 LYS LYS C . n 
C 1 158 ARG 158 158 158 ARG ARG C . n 
C 1 159 TYR 159 159 159 TYR TYR C . n 
C 1 160 GLU 160 160 160 GLU GLU C . n 
C 1 161 GLU 161 161 161 GLU GLU C . n 
C 1 162 GLY 162 162 162 GLY GLY C . n 
C 1 163 MET 163 163 163 MET MET C . n 
C 1 164 ARG 164 164 164 ARG ARG C . n 
C 1 165 ARG 165 165 165 ARG ARG C . n 
C 1 166 GLU 166 166 166 GLU GLU C . n 
C 1 167 GLU 167 167 167 GLU GLU C . n 
C 1 168 HIS 168 168 168 HIS HIS C . n 
C 1 169 TRP 169 169 169 TRP TRP C . n 
C 1 170 GLU 170 170 170 GLU GLU C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 MET 172 172 172 MET MET C . n 
C 1 173 LEU 173 173 173 LEU LEU C . n 
C 1 174 GLU 174 174 174 GLU GLU C . n 
C 1 175 ASP 175 175 175 ASP ASP C . n 
C 1 176 SER 176 176 176 SER SER C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 ASN 178 178 178 ASN ASN C . n 
C 1 179 MET 179 179 179 MET MET C . n 
C 1 180 LEU 180 180 180 LEU LEU C . n 
C 1 181 ALA 181 181 181 ALA ALA C . n 
C 1 182 ALA 182 182 182 ALA ALA C . n 
C 1 183 LEU 183 183 183 LEU LEU C . n 
C 1 184 PRO 184 184 184 PRO PRO C . n 
C 1 185 VAL 185 185 185 VAL VAL C . n 
C 1 186 ILE 186 186 186 ILE ILE C . n 
C 1 187 ALA 187 187 187 ALA ALA C . n 
C 1 188 ALA 188 188 188 ALA ALA C . n 
C 1 189 TYR 189 189 189 TYR TYR C . n 
C 1 190 ILE 190 190 190 ILE ILE C . n 
C 1 191 TYR 191 191 191 TYR TYR C . n 
C 1 192 ARG 192 192 192 ARG ARG C . n 
C 1 193 ARG 193 193 193 ARG ARG C . n 
C 1 194 LYS 194 194 194 LYS LYS C . n 
C 1 195 TYR 195 195 195 TYR TYR C . n 
C 1 196 LYS 196 196 196 LYS LYS C . n 
C 1 197 GLY 197 197 197 GLY GLY C . n 
C 1 198 ASP 198 198 198 ASP ASP C . n 
C 1 199 THR 199 199 199 THR THR C . n 
C 1 200 HIS 200 200 200 HIS HIS C . n 
C 1 201 ILE 201 201 201 ILE ILE C . n 
C 1 202 ALA 202 202 202 ALA ALA C . n 
C 1 203 PRO 203 203 203 PRO PRO C . n 
C 1 204 ASP 204 204 204 ASP ASP C . n 
C 1 205 PRO 205 205 205 PRO PRO C . n 
C 1 206 ASN 206 206 206 ASN ASN C . n 
C 1 207 LEU 207 207 207 LEU LEU C . n 
C 1 208 ASP 208 208 208 ASP ASP C . n 
C 1 209 TRP 209 209 209 TRP TRP C . n 
C 1 210 SER 210 210 210 SER SER C . n 
C 1 211 ALA 211 211 211 ALA ALA C . n 
C 1 212 ASN 212 212 212 ASN ASN C . n 
C 1 213 LEU 213 213 213 LEU LEU C . n 
C 1 214 ALA 214 214 214 ALA ALA C . n 
C 1 215 HIS 215 215 215 HIS HIS C . n 
C 1 216 MET 216 216 216 MET MET C . n 
C 1 217 MET 217 217 217 MET MET C . n 
C 1 218 GLY 218 218 218 GLY GLY C . n 
C 1 219 PHE 219 219 219 PHE PHE C . n 
C 1 220 ASP 220 220 220 ASP ASP C . n 
C 1 221 ASP 221 221 221 ASP ASP C . n 
C 1 222 PHE 222 222 222 PHE PHE C . n 
C 1 223 GLU 223 223 223 GLU GLU C . n 
C 1 224 VAL 224 224 224 VAL VAL C . n 
C 1 225 TYR 225 225 225 TYR TYR C . n 
C 1 226 GLU 226 226 226 GLU GLU C . n 
C 1 227 LEU 227 227 227 LEU LEU C . n 
C 1 228 PHE 228 228 228 PHE PHE C . n 
C 1 229 ARG 229 229 229 ARG ARG C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 TYR 231 231 231 TYR TYR C . n 
C 1 232 MET 232 232 232 MET MET C . n 
C 1 233 PHE 233 233 233 PHE PHE C . n 
C 1 234 LEU 234 234 234 LEU LEU C . n 
C 1 235 HIS 235 235 235 HIS HIS C . n 
C 1 236 SER 236 236 236 SER SER C . n 
C 1 237 ASP 237 237 237 ASP ASP C . n 
C 1 238 HIS 238 238 238 HIS HIS C . n 
C 1 239 GLU 239 239 239 GLU GLU C . n 
C 1 240 GLY 240 240 240 GLY GLY C . n 
C 1 241 GLY 241 241 241 GLY GLY C . n 
C 1 242 ASN 242 242 242 ASN ASN C . n 
C 1 243 VAL 243 243 243 VAL VAL C . n 
C 1 244 SER 244 244 244 SER SER C . n 
C 1 245 ALA 245 245 245 ALA ALA C . n 
C 1 246 HIS 246 246 246 HIS HIS C . n 
C 1 247 THR 247 247 247 THR THR C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 LEU 249 249 249 LEU LEU C . n 
C 1 250 LEU 250 250 250 LEU LEU C . n 
C 1 251 VAL 251 251 251 VAL VAL C . n 
C 1 252 ASN 252 252 252 ASN ASN C . n 
C 1 253 SER 253 253 253 SER SER C . n 
C 1 254 ALA 254 254 254 ALA ALA C . n 
C 1 255 TYR 255 255 255 TYR TYR C . n 
C 1 256 SER 256 256 256 SER SER C . n 
C 1 257 ASP 257 257 257 ASP ASP C . n 
C 1 258 ILE 258 258 258 ILE ILE C . n 
C 1 259 TYR 259 259 259 TYR TYR C . n 
C 1 260 ARG 260 260 260 ARG ARG C . n 
C 1 261 SER 261 261 261 SER SER C . n 
C 1 262 PHE 262 262 262 PHE PHE C . n 
C 1 263 SER 263 263 263 SER SER C . n 
C 1 264 ALA 264 264 264 ALA ALA C . n 
C 1 265 ALA 265 265 265 ALA ALA C . n 
C 1 266 MET 266 266 266 MET MET C . n 
C 1 267 ASN 267 267 267 ASN ASN C . n 
C 1 268 GLY 268 268 268 GLY GLY C . n 
C 1 269 LEU 269 269 269 LEU LEU C . n 
C 1 270 ALA 270 270 270 ALA ALA C . n 
C 1 271 GLY 271 271 271 GLY GLY C . n 
C 1 272 PRO 272 272 272 PRO PRO C . n 
C 1 273 LEU 273 273 273 LEU LEU C . n 
C 1 274 HIS 274 274 274 HIS HIS C . n 
C 1 275 GLY 275 275 275 GLY GLY C . n 
C 1 276 LEU 276 276 276 LEU LEU C . n 
C 1 277 ALA 277 277 277 ALA ALA C . n 
C 1 278 ASN 278 278 278 ASN ASN C . n 
C 1 279 GLN 279 279 279 GLN GLN C . n 
C 1 280 GLU 280 280 280 GLU GLU C . n 
C 1 281 VAL 281 281 281 VAL VAL C . n 
C 1 282 LEU 282 282 282 LEU LEU C . n 
C 1 283 ARG 283 283 283 ARG ARG C . n 
C 1 284 TRP 284 284 284 TRP TRP C . n 
C 1 285 ILE 285 285 285 ILE ILE C . n 
C 1 286 GLN 286 286 286 GLN GLN C . n 
C 1 287 MET 287 287 287 MET MET C . n 
C 1 288 LEU 288 288 288 LEU LEU C . n 
C 1 289 TYR 289 289 289 TYR TYR C . n 
C 1 290 LYS 290 290 290 LYS LYS C . n 
C 1 291 LYS 291 291 291 LYS LYS C . n 
C 1 292 PHE 292 292 292 PHE PHE C . n 
C 1 293 GLY 293 293 293 GLY GLY C . n 
C 1 294 GLY 294 294 294 GLY GLY C . n 
C 1 295 VAL 295 295 295 VAL VAL C . n 
C 1 296 PRO 296 296 296 PRO PRO C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 LYS 298 298 298 LYS LYS C . n 
C 1 299 GLU 299 299 299 GLU GLU C . n 
C 1 300 GLN 300 300 300 GLN GLN C . n 
C 1 301 LEU 301 301 301 LEU LEU C . n 
C 1 302 GLU 302 302 302 GLU GLU C . n 
C 1 303 ARG 303 303 303 ARG ARG C . n 
C 1 304 PHE 304 304 304 PHE PHE C . n 
C 1 305 ALA 305 305 305 ALA ALA C . n 
C 1 306 TRP 306 306 306 TRP TRP C . n 
C 1 307 ASP 307 307 307 ASP ASP C . n 
C 1 308 THR 308 308 308 THR THR C . n 
C 1 309 LEU 309 309 309 LEU LEU C . n 
C 1 310 ASN 310 310 310 ASN ASN C . n 
C 1 311 SER 311 311 311 SER SER C . n 
C 1 312 GLY 312 312 312 GLY GLY C . n 
C 1 313 GLN 313 313 313 GLN GLN C . n 
C 1 314 VAL 314 314 314 VAL VAL C . n 
C 1 315 ILE 315 315 315 ILE ILE C . n 
C 1 316 PRO 316 316 316 PRO PRO C . n 
C 1 317 GLY 317 317 317 GLY GLY C . n 
C 1 318 TYR 318 318 318 TYR TYR C . n 
C 1 319 GLY 319 319 319 GLY GLY C . n 
C 1 320 HIS 320 320 320 HIS HIS C . n 
C 1 321 ALA 321 321 321 ALA ALA C . n 
C 1 322 VAL 322 322 322 VAL VAL C . n 
C 1 323 LEU 323 323 323 LEU LEU C . n 
C 1 324 ARG 324 324 324 ARG ARG C . n 
C 1 325 VAL 325 325 325 VAL VAL C . n 
C 1 326 THR 326 326 326 THR THR C . n 
C 1 327 ASP 327 327 327 ASP ASP C . n 
C 1 328 PRO 328 328 328 PRO PRO C . n 
C 1 329 ARG 329 329 329 ARG ARG C . n 
C 1 330 TYR 330 330 330 TYR TYR C . n 
C 1 331 VAL 331 331 331 VAL VAL C . n 
C 1 332 ALA 332 332 332 ALA ALA C . n 
C 1 333 GLN 333 333 333 GLN GLN C . n 
C 1 334 ARG 334 334 334 ARG ARG C . n 
C 1 335 ASP 335 335 335 ASP ASP C . n 
C 1 336 PHE 336 336 336 PHE PHE C . n 
C 1 337 ALA 337 337 337 ALA ALA C . n 
C 1 338 LEU 338 338 338 LEU LEU C . n 
C 1 339 LYS 339 339 339 LYS LYS C . n 
C 1 340 HIS 340 340 340 HIS HIS C . n 
C 1 341 LEU 341 341 341 LEU LEU C . n 
C 1 342 PRO 342 342 342 PRO PRO C . n 
C 1 343 ASP 343 343 343 ASP ASP C . n 
C 1 344 ASP 344 344 344 ASP ASP C . n 
C 1 345 GLU 345 345 345 GLU GLU C . n 
C 1 346 LEU 346 346 346 LEU LEU C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 LYS 348 348 348 LYS LYS C . n 
C 1 349 ILE 349 349 349 ILE ILE C . n 
C 1 350 VAL 350 350 350 VAL VAL C . n 
C 1 351 SER 351 351 351 SER SER C . n 
C 1 352 LEU 352 352 352 LEU LEU C . n 
C 1 353 CYS 353 353 353 CYS CYS C . n 
C 1 354 TYR 354 354 354 TYR TYR C . n 
C 1 355 GLU 355 355 355 GLU GLU C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 ILE 357 357 357 ILE ILE C . n 
C 1 358 PRO 358 358 358 PRO PRO C . n 
C 1 359 GLU 359 359 359 GLU GLU C . n 
C 1 360 VAL 360 360 360 VAL VAL C . n 
C 1 361 LEU 361 361 361 LEU LEU C . n 
C 1 362 LYS 362 362 362 LYS LYS C . n 
C 1 363 LYS 363 363 363 LYS LYS C . n 
C 1 364 HIS 364 364 364 HIS HIS C . n 
C 1 365 GLY 365 365 365 GLY GLY C . n 
C 1 366 LYS 366 366 366 LYS LYS C . n 
C 1 367 ALA 367 367 367 ALA ALA C . n 
C 1 368 LYS 368 368 368 LYS LYS C . n 
C 1 369 ASN 369 369 369 ASN ASN C . n 
C 1 370 PRO 370 370 370 PRO PRO C . n 
C 1 371 TRP 371 371 371 TRP TRP C . n 
C 1 372 PRO 372 372 372 PRO PRO C . n 
C 1 373 ASN 373 373 373 ASN ASN C . n 
C 1 374 VAL 374 374 374 VAL VAL C . n 
C 1 375 ASP 375 375 375 ASP ASP C . n 
C 1 376 ALA 376 376 376 ALA ALA C . n 
C 1 377 HIS 377 377 377 HIS HIS C . n 
C 1 378 SER 378 378 378 SER SER C . n 
C 1 379 GLY 379 379 379 GLY GLY C . n 
C 1 380 VAL 380 380 380 VAL VAL C . n 
C 1 381 LEU 381 381 381 LEU LEU C . n 
C 1 382 LEU 382 382 382 LEU LEU C . n 
C 1 383 TRP 383 383 383 TRP TRP C . n 
C 1 384 HIS 384 384 384 HIS HIS C . n 
C 1 385 TYR 385 385 385 TYR TYR C . n 
C 1 386 GLY 386 386 386 GLY GLY C . n 
C 1 387 ILE 387 387 387 ILE ILE C . n 
C 1 388 ARG 388 388 388 ARG ARG C . n 
C 1 389 GLU 389 389 389 GLU GLU C . n 
C 1 390 TYR 390 390 390 TYR TYR C . n 
C 1 391 ASP 391 391 391 ASP ASP C . n 
C 1 392 PHE 392 392 392 PHE PHE C . n 
C 1 393 TYR 393 393 393 TYR TYR C . n 
C 1 394 THR 394 394 394 THR THR C . n 
C 1 395 VAL 395 395 395 VAL VAL C . n 
C 1 396 LEU 396 396 396 LEU LEU C . n 
C 1 397 PHE 397 397 397 PHE PHE C . n 
C 1 398 GLY 398 398 398 GLY GLY C . n 
C 1 399 VAL 399 399 399 VAL VAL C . n 
C 1 400 SER 400 400 400 SER SER C . n 
C 1 401 ARG 401 401 401 ARG ARG C . n 
C 1 402 ALA 402 402 402 ALA ALA C . n 
C 1 403 LEU 403 403 403 LEU LEU C . n 
C 1 404 GLY 404 404 404 GLY GLY C . n 
C 1 405 CYS 405 405 405 CYS CYS C . n 
C 1 406 THR 406 406 406 THR THR C . n 
C 1 407 ALA 407 407 407 ALA ALA C . n 
C 1 408 GLN 408 408 408 GLN GLN C . n 
C 1 409 ALA 409 409 409 ALA ALA C . n 
C 1 410 ILE 410 410 410 ILE ILE C . n 
C 1 411 LEU 411 411 411 LEU LEU C . n 
C 1 412 VAL 412 412 412 VAL VAL C . n 
C 1 413 ARG 413 413 413 ARG ARG C . n 
C 1 414 GLY 414 414 414 GLY GLY C . n 
C 1 415 TYR 415 415 415 TYR TYR C . n 
C 1 416 MET 416 416 416 MET MET C . n 
C 1 417 LEU 417 417 417 LEU LEU C . n 
C 1 418 PRO 418 418 418 PRO PRO C . n 
C 1 419 ILE 419 419 419 ILE ILE C . n 
C 1 420 GLU 420 420 420 GLU GLU C . n 
C 1 421 ARG 421 421 421 ARG ARG C . n 
C 1 422 PRO 422 422 422 PRO PRO C . n 
C 1 423 LYS 423 423 423 LYS LYS C . n 
C 1 424 SER 424 424 424 SER SER C . n 
C 1 425 ILE 425 425 425 ILE ILE C . n 
C 1 426 THR 426 426 426 THR THR C . n 
C 1 427 THR 427 427 427 THR THR C . n 
C 1 428 ARG 428 428 428 ARG ARG C . n 
C 1 429 TRP 429 429 429 TRP TRP C . n 
C 1 430 VAL 430 430 430 VAL VAL C . n 
C 1 431 LYS 431 431 431 LYS LYS C . n 
C 1 432 GLU 432 432 432 GLU GLU C . n 
C 1 433 VAL 433 433 433 VAL VAL C . n 
C 1 434 ALA 434 434 434 ALA ALA C . n 
C 1 435 GLU 435 435 435 GLU GLU C . n 
C 1 436 SER 436 436 436 SER SER C . n 
C 1 437 LEU 437 437 437 LEU LEU C . n 
C 1 438 PRO 438 438 438 PRO PRO C . n 
C 1 439 VAL 439 439 439 VAL VAL C . n 
C 1 440 ALA 440 440 440 ALA ALA C . n 
C 1 441 GLY 441 441 441 GLY GLY C . n 
C 1 442 SER 442 442 442 SER SER C . n 
C 1 443 LYS 443 443 ?   ?   ?   C . n 
C 1 444 LEU 444 444 ?   ?   ?   C . n 
C 1 445 ALA 445 445 ?   ?   ?   C . n 
C 1 446 ALA 446 446 ?   ?   ?   C . n 
C 1 447 ALA 447 447 ?   ?   ?   C . n 
C 1 448 LEU 448 448 ?   ?   ?   C . n 
C 1 449 GLU 449 449 ?   ?   ?   C . n 
D 1 1   MET 1   1   1   MET MET D . n 
D 1 2   LYS 2   2   2   LYS LYS D . n 
D 1 3   LEU 3   3   3   LEU LEU D . n 
D 1 4   LYS 4   4   4   LYS LYS D . n 
D 1 5   GLU 5   5   5   GLU GLU D . n 
D 1 6   ARG 6   6   6   ARG ARG D . n 
D 1 7   LEU 7   7   7   LEU LEU D . n 
D 1 8   ALA 8   8   8   ALA ALA D . n 
D 1 9   GLU 9   9   9   GLU GLU D . n 
D 1 10  LEU 10  10  10  LEU LEU D . n 
D 1 11  ILE 11  11  11  ILE ILE D . n 
D 1 12  PRO 12  12  12  PRO PRO D . n 
D 1 13  GLN 13  13  13  GLN GLN D . n 
D 1 14  TRP 14  14  14  TRP TRP D . n 
D 1 15  ARG 15  15  15  ARG ARG D . n 
D 1 16  ALA 16  16  16  ALA ALA D . n 
D 1 17  GLU 17  17  17  GLU GLU D . n 
D 1 18  VAL 18  18  18  VAL VAL D . n 
D 1 19  ALA 19  19  19  ALA ALA D . n 
D 1 20  GLU 20  20  20  GLU GLU D . n 
D 1 21  ILE 21  21  21  ILE ILE D . n 
D 1 22  ARG 22  22  22  ARG ARG D . n 
D 1 23  LYS 23  23  23  LYS LYS D . n 
D 1 24  LYS 24  24  24  LYS LYS D . n 
D 1 25  TYR 25  25  25  TYR TYR D . n 
D 1 26  GLY 26  26  26  GLY GLY D . n 
D 1 27  ASN 27  27  27  ASN ASN D . n 
D 1 28  ARG 28  28  28  ARG ARG D . n 
D 1 29  LYS 29  29  29  LYS LYS D . n 
D 1 30  THR 30  30  30  THR THR D . n 
D 1 31  MET 31  31  31  MET MET D . n 
D 1 32  ASP 32  32  32  ASP ASP D . n 
D 1 33  CYS 33  33  33  CYS CYS D . n 
D 1 34  THR 34  34  34  THR THR D . n 
D 1 35  ILE 35  35  35  ILE ILE D . n 
D 1 36  GLY 36  36  36  GLY GLY D . n 
D 1 37  HIS 37  37  37  HIS HIS D . n 
D 1 38  ALA 38  38  38  ALA ALA D . n 
D 1 39  TYR 39  39  39  TYR TYR D . n 
D 1 40  GLY 40  40  40  GLY GLY D . n 
D 1 41  GLY 41  41  41  GLY GLY D . n 
D 1 42  MET 42  42  42  MET MET D . n 
D 1 43  ARG 43  43  43  ARG ARG D . n 
D 1 44  GLY 44  44  44  GLY GLY D . n 
D 1 45  LEU 45  45  45  LEU LEU D . n 
D 1 46  LYS 46  46  46  LYS LYS D . n 
D 1 47  ALA 47  47  47  ALA ALA D . n 
D 1 48  LEU 48  48  48  LEU LEU D . n 
D 1 49  VAL 49  49  49  VAL VAL D . n 
D 1 50  CYS 50  50  50  CYS CYS D . n 
D 1 51  ASP 51  51  51  ASP ASP D . n 
D 1 52  THR 52  52  52  THR THR D . n 
D 1 53  SER 53  53  53  SER SER D . n 
D 1 54  GLU 54  54  54  GLU GLU D . n 
D 1 55  VAL 55  55  55  VAL VAL D . n 
D 1 56  PHE 56  56  56  PHE PHE D . n 
D 1 57  PRO 57  57  57  PRO PRO D . n 
D 1 58  ASP 58  58  58  ASP ASP D . n 
D 1 59  GLU 59  59  59  GLU GLU D . n 
D 1 60  GLY 60  60  60  GLY GLY D . n 
D 1 61  VAL 61  61  61  VAL VAL D . n 
D 1 62  LYS 62  62  62  LYS LYS D . n 
D 1 63  PHE 63  63  63  PHE PHE D . n 
D 1 64  ARG 64  64  64  ARG ARG D . n 
D 1 65  GLY 65  65  65  GLY GLY D . n 
D 1 66  TYR 66  66  66  TYR TYR D . n 
D 1 67  THR 67  67  67  THR THR D . n 
D 1 68  ILE 68  68  68  ILE ILE D . n 
D 1 69  PRO 69  69  69  PRO PRO D . n 
D 1 70  GLU 70  70  70  GLU GLU D . n 
D 1 71  LEU 71  71  71  LEU LEU D . n 
D 1 72  ARG 72  72  72  ARG ARG D . n 
D 1 73  GLU 73  73  73  GLU GLU D . n 
D 1 74  GLY 74  74  74  GLY GLY D . n 
D 1 75  PRO 75  75  75  PRO PRO D . n 
D 1 76  HIS 76  76  76  HIS HIS D . n 
D 1 77  LYS 77  77  77  LYS LYS D . n 
D 1 78  LEU 78  78  78  LEU LEU D . n 
D 1 79  PRO 79  79  79  PRO PRO D . n 
D 1 80  THR 80  80  80  THR THR D . n 
D 1 81  ALA 81  81  81  ALA ALA D . n 
D 1 82  GLU 82  82  82  GLU GLU D . n 
D 1 83  GLY 83  83  83  GLY GLY D . n 
D 1 84  GLY 84  84  84  GLY GLY D . n 
D 1 85  PHE 85  85  85  PHE PHE D . n 
D 1 86  GLU 86  86  86  GLU GLU D . n 
D 1 87  PRO 87  87  87  PRO PRO D . n 
D 1 88  LEU 88  88  88  LEU LEU D . n 
D 1 89  PRO 89  89  89  PRO PRO D . n 
D 1 90  GLU 90  90  90  GLU GLU D . n 
D 1 91  GLY 91  91  91  GLY GLY D . n 
D 1 92  LEU 92  92  92  LEU LEU D . n 
D 1 93  TRP 93  93  93  TRP TRP D . n 
D 1 94  TYR 94  94  94  TYR TYR D . n 
D 1 95  LEU 95  95  95  LEU LEU D . n 
D 1 96  LEU 96  96  96  LEU LEU D . n 
D 1 97  LEU 97  97  97  LEU LEU D . n 
D 1 98  THR 98  98  98  THR THR D . n 
D 1 99  GLY 99  99  99  GLY GLY D . n 
D 1 100 GLU 100 100 100 GLU GLU D . n 
D 1 101 LEU 101 101 101 LEU LEU D . n 
D 1 102 PRO 102 102 102 PRO PRO D . n 
D 1 103 THR 103 103 103 THR THR D . n 
D 1 104 GLU 104 104 104 GLU GLU D . n 
D 1 105 GLU 105 105 105 GLU GLU D . n 
D 1 106 ASP 106 106 106 ASP ASP D . n 
D 1 107 VAL 107 107 107 VAL VAL D . n 
D 1 108 LYS 108 108 108 LYS LYS D . n 
D 1 109 GLU 109 109 109 GLU GLU D . n 
D 1 110 ILE 110 110 110 ILE ILE D . n 
D 1 111 SER 111 111 111 SER SER D . n 
D 1 112 ALA 112 112 112 ALA ALA D . n 
D 1 113 GLU 113 113 113 GLU GLU D . n 
D 1 114 PHE 114 114 114 PHE PHE D . n 
D 1 115 THR 115 115 115 THR THR D . n 
D 1 116 LYS 116 116 116 LYS LYS D . n 
D 1 117 ARG 117 117 117 ARG ARG D . n 
D 1 118 MET 118 118 118 MET MET D . n 
D 1 119 GLN 119 119 119 GLN GLN D . n 
D 1 120 ASN 120 120 120 ASN ASN D . n 
D 1 121 VAL 121 121 121 VAL VAL D . n 
D 1 122 PRO 122 122 122 PRO PRO D . n 
D 1 123 GLN 123 123 123 GLN GLN D . n 
D 1 124 TYR 124 124 124 TYR TYR D . n 
D 1 125 VAL 125 125 125 VAL VAL D . n 
D 1 126 PHE 126 126 126 PHE PHE D . n 
D 1 127 ASP 127 127 127 ASP ASP D . n 
D 1 128 VAL 128 128 128 VAL VAL D . n 
D 1 129 LEU 129 129 129 LEU LEU D . n 
D 1 130 ARG 130 130 130 ARG ARG D . n 
D 1 131 ALA 131 131 131 ALA ALA D . n 
D 1 132 MET 132 132 132 MET MET D . n 
D 1 133 PRO 133 133 133 PRO PRO D . n 
D 1 134 VAL 134 134 134 VAL VAL D . n 
D 1 135 ASP 135 135 135 ASP ASP D . n 
D 1 136 THR 136 136 136 THR THR D . n 
D 1 137 HIS 137 137 137 HIS HIS D . n 
D 1 138 PRO 138 138 138 PRO PRO D . n 
D 1 139 MET 139 139 139 MET MET D . n 
D 1 140 THR 140 140 140 THR THR D . n 
D 1 141 MET 141 141 141 MET MET D . n 
D 1 142 PHE 142 142 142 PHE PHE D . n 
D 1 143 ALA 143 143 143 ALA ALA D . n 
D 1 144 ALA 144 144 144 ALA ALA D . n 
D 1 145 GLY 145 145 145 GLY GLY D . n 
D 1 146 ILE 146 146 146 ILE ILE D . n 
D 1 147 LEU 147 147 147 LEU LEU D . n 
D 1 148 ALA 148 148 148 ALA ALA D . n 
D 1 149 MET 149 149 149 MET MET D . n 
D 1 150 GLN 150 150 150 GLN GLN D . n 
D 1 151 ARG 151 151 151 ARG ARG D . n 
D 1 152 GLU 152 152 152 GLU GLU D . n 
D 1 153 SER 153 153 153 SER SER D . n 
D 1 154 VAL 154 154 154 VAL VAL D . n 
D 1 155 PHE 155 155 155 PHE PHE D . n 
D 1 156 ALA 156 156 156 ALA ALA D . n 
D 1 157 LYS 157 157 157 LYS LYS D . n 
D 1 158 ARG 158 158 158 ARG ARG D . n 
D 1 159 TYR 159 159 159 TYR TYR D . n 
D 1 160 GLU 160 160 160 GLU GLU D . n 
D 1 161 GLU 161 161 161 GLU GLU D . n 
D 1 162 GLY 162 162 162 GLY GLY D . n 
D 1 163 MET 163 163 163 MET MET D . n 
D 1 164 ARG 164 164 164 ARG ARG D . n 
D 1 165 ARG 165 165 165 ARG ARG D . n 
D 1 166 GLU 166 166 166 GLU GLU D . n 
D 1 167 GLU 167 167 167 GLU GLU D . n 
D 1 168 HIS 168 168 168 HIS HIS D . n 
D 1 169 TRP 169 169 169 TRP TRP D . n 
D 1 170 GLU 170 170 170 GLU GLU D . n 
D 1 171 ALA 171 171 171 ALA ALA D . n 
D 1 172 MET 172 172 172 MET MET D . n 
D 1 173 LEU 173 173 173 LEU LEU D . n 
D 1 174 GLU 174 174 174 GLU GLU D . n 
D 1 175 ASP 175 175 175 ASP ASP D . n 
D 1 176 SER 176 176 176 SER SER D . n 
D 1 177 LEU 177 177 177 LEU LEU D . n 
D 1 178 ASN 178 178 178 ASN ASN D . n 
D 1 179 MET 179 179 179 MET MET D . n 
D 1 180 LEU 180 180 180 LEU LEU D . n 
D 1 181 ALA 181 181 181 ALA ALA D . n 
D 1 182 ALA 182 182 182 ALA ALA D . n 
D 1 183 LEU 183 183 183 LEU LEU D . n 
D 1 184 PRO 184 184 184 PRO PRO D . n 
D 1 185 VAL 185 185 185 VAL VAL D . n 
D 1 186 ILE 186 186 186 ILE ILE D . n 
D 1 187 ALA 187 187 187 ALA ALA D . n 
D 1 188 ALA 188 188 188 ALA ALA D . n 
D 1 189 TYR 189 189 189 TYR TYR D . n 
D 1 190 ILE 190 190 190 ILE ILE D . n 
D 1 191 TYR 191 191 191 TYR TYR D . n 
D 1 192 ARG 192 192 192 ARG ARG D . n 
D 1 193 ARG 193 193 193 ARG ARG D . n 
D 1 194 LYS 194 194 194 LYS LYS D . n 
D 1 195 TYR 195 195 195 TYR TYR D . n 
D 1 196 LYS 196 196 196 LYS LYS D . n 
D 1 197 GLY 197 197 197 GLY GLY D . n 
D 1 198 ASP 198 198 198 ASP ASP D . n 
D 1 199 THR 199 199 199 THR THR D . n 
D 1 200 HIS 200 200 200 HIS HIS D . n 
D 1 201 ILE 201 201 201 ILE ILE D . n 
D 1 202 ALA 202 202 202 ALA ALA D . n 
D 1 203 PRO 203 203 203 PRO PRO D . n 
D 1 204 ASP 204 204 204 ASP ASP D . n 
D 1 205 PRO 205 205 205 PRO PRO D . n 
D 1 206 ASN 206 206 206 ASN ASN D . n 
D 1 207 LEU 207 207 207 LEU LEU D . n 
D 1 208 ASP 208 208 208 ASP ASP D . n 
D 1 209 TRP 209 209 209 TRP TRP D . n 
D 1 210 SER 210 210 210 SER SER D . n 
D 1 211 ALA 211 211 211 ALA ALA D . n 
D 1 212 ASN 212 212 212 ASN ASN D . n 
D 1 213 LEU 213 213 213 LEU LEU D . n 
D 1 214 ALA 214 214 214 ALA ALA D . n 
D 1 215 HIS 215 215 215 HIS HIS D . n 
D 1 216 MET 216 216 216 MET MET D . n 
D 1 217 MET 217 217 217 MET MET D . n 
D 1 218 GLY 218 218 218 GLY GLY D . n 
D 1 219 PHE 219 219 219 PHE PHE D . n 
D 1 220 ASP 220 220 220 ASP ASP D . n 
D 1 221 ASP 221 221 221 ASP ASP D . n 
D 1 222 PHE 222 222 222 PHE PHE D . n 
D 1 223 GLU 223 223 223 GLU GLU D . n 
D 1 224 VAL 224 224 224 VAL VAL D . n 
D 1 225 TYR 225 225 225 TYR TYR D . n 
D 1 226 GLU 226 226 226 GLU GLU D . n 
D 1 227 LEU 227 227 227 LEU LEU D . n 
D 1 228 PHE 228 228 228 PHE PHE D . n 
D 1 229 ARG 229 229 229 ARG ARG D . n 
D 1 230 LEU 230 230 230 LEU LEU D . n 
D 1 231 TYR 231 231 231 TYR TYR D . n 
D 1 232 MET 232 232 232 MET MET D . n 
D 1 233 PHE 233 233 233 PHE PHE D . n 
D 1 234 LEU 234 234 234 LEU LEU D . n 
D 1 235 HIS 235 235 235 HIS HIS D . n 
D 1 236 SER 236 236 236 SER SER D . n 
D 1 237 ASP 237 237 237 ASP ASP D . n 
D 1 238 HIS 238 238 238 HIS HIS D . n 
D 1 239 GLU 239 239 239 GLU GLU D . n 
D 1 240 GLY 240 240 240 GLY GLY D . n 
D 1 241 GLY 241 241 241 GLY GLY D . n 
D 1 242 ASN 242 242 242 ASN ASN D . n 
D 1 243 VAL 243 243 243 VAL VAL D . n 
D 1 244 SER 244 244 244 SER SER D . n 
D 1 245 ALA 245 245 245 ALA ALA D . n 
D 1 246 HIS 246 246 246 HIS HIS D . n 
D 1 247 THR 247 247 247 THR THR D . n 
D 1 248 ASN 248 248 248 ASN ASN D . n 
D 1 249 LEU 249 249 249 LEU LEU D . n 
D 1 250 LEU 250 250 250 LEU LEU D . n 
D 1 251 VAL 251 251 251 VAL VAL D . n 
D 1 252 ASN 252 252 252 ASN ASN D . n 
D 1 253 SER 253 253 253 SER SER D . n 
D 1 254 ALA 254 254 254 ALA ALA D . n 
D 1 255 TYR 255 255 255 TYR TYR D . n 
D 1 256 SER 256 256 256 SER SER D . n 
D 1 257 ASP 257 257 257 ASP ASP D . n 
D 1 258 ILE 258 258 258 ILE ILE D . n 
D 1 259 TYR 259 259 259 TYR TYR D . n 
D 1 260 ARG 260 260 260 ARG ARG D . n 
D 1 261 SER 261 261 261 SER SER D . n 
D 1 262 PHE 262 262 262 PHE PHE D . n 
D 1 263 SER 263 263 263 SER SER D . n 
D 1 264 ALA 264 264 264 ALA ALA D . n 
D 1 265 ALA 265 265 265 ALA ALA D . n 
D 1 266 MET 266 266 266 MET MET D . n 
D 1 267 ASN 267 267 267 ASN ASN D . n 
D 1 268 GLY 268 268 268 GLY GLY D . n 
D 1 269 LEU 269 269 269 LEU LEU D . n 
D 1 270 ALA 270 270 270 ALA ALA D . n 
D 1 271 GLY 271 271 271 GLY GLY D . n 
D 1 272 PRO 272 272 272 PRO PRO D . n 
D 1 273 LEU 273 273 273 LEU LEU D . n 
D 1 274 HIS 274 274 274 HIS HIS D . n 
D 1 275 GLY 275 275 275 GLY GLY D . n 
D 1 276 LEU 276 276 276 LEU LEU D . n 
D 1 277 ALA 277 277 277 ALA ALA D . n 
D 1 278 ASN 278 278 278 ASN ASN D . n 
D 1 279 GLN 279 279 279 GLN GLN D . n 
D 1 280 GLU 280 280 280 GLU GLU D . n 
D 1 281 VAL 281 281 281 VAL VAL D . n 
D 1 282 LEU 282 282 282 LEU LEU D . n 
D 1 283 ARG 283 283 283 ARG ARG D . n 
D 1 284 TRP 284 284 284 TRP TRP D . n 
D 1 285 ILE 285 285 285 ILE ILE D . n 
D 1 286 GLN 286 286 286 GLN GLN D . n 
D 1 287 MET 287 287 287 MET MET D . n 
D 1 288 LEU 288 288 288 LEU LEU D . n 
D 1 289 TYR 289 289 289 TYR TYR D . n 
D 1 290 LYS 290 290 290 LYS LYS D . n 
D 1 291 LYS 291 291 291 LYS LYS D . n 
D 1 292 PHE 292 292 292 PHE PHE D . n 
D 1 293 GLY 293 293 293 GLY GLY D . n 
D 1 294 GLY 294 294 294 GLY GLY D . n 
D 1 295 VAL 295 295 295 VAL VAL D . n 
D 1 296 PRO 296 296 296 PRO PRO D . n 
D 1 297 THR 297 297 297 THR THR D . n 
D 1 298 LYS 298 298 298 LYS LYS D . n 
D 1 299 GLU 299 299 299 GLU GLU D . n 
D 1 300 GLN 300 300 300 GLN GLN D . n 
D 1 301 LEU 301 301 301 LEU LEU D . n 
D 1 302 GLU 302 302 302 GLU GLU D . n 
D 1 303 ARG 303 303 303 ARG ARG D . n 
D 1 304 PHE 304 304 304 PHE PHE D . n 
D 1 305 ALA 305 305 305 ALA ALA D . n 
D 1 306 TRP 306 306 306 TRP TRP D . n 
D 1 307 ASP 307 307 307 ASP ASP D . n 
D 1 308 THR 308 308 308 THR THR D . n 
D 1 309 LEU 309 309 309 LEU LEU D . n 
D 1 310 ASN 310 310 310 ASN ASN D . n 
D 1 311 SER 311 311 311 SER SER D . n 
D 1 312 GLY 312 312 312 GLY GLY D . n 
D 1 313 GLN 313 313 313 GLN GLN D . n 
D 1 314 VAL 314 314 314 VAL VAL D . n 
D 1 315 ILE 315 315 315 ILE ILE D . n 
D 1 316 PRO 316 316 316 PRO PRO D . n 
D 1 317 GLY 317 317 317 GLY GLY D . n 
D 1 318 TYR 318 318 318 TYR TYR D . n 
D 1 319 GLY 319 319 319 GLY GLY D . n 
D 1 320 HIS 320 320 320 HIS HIS D . n 
D 1 321 ALA 321 321 321 ALA ALA D . n 
D 1 322 VAL 322 322 322 VAL VAL D . n 
D 1 323 LEU 323 323 323 LEU LEU D . n 
D 1 324 ARG 324 324 324 ARG ARG D . n 
D 1 325 VAL 325 325 325 VAL VAL D . n 
D 1 326 THR 326 326 326 THR THR D . n 
D 1 327 ASP 327 327 327 ASP ASP D . n 
D 1 328 PRO 328 328 328 PRO PRO D . n 
D 1 329 ARG 329 329 329 ARG ARG D . n 
D 1 330 TYR 330 330 330 TYR TYR D . n 
D 1 331 VAL 331 331 331 VAL VAL D . n 
D 1 332 ALA 332 332 332 ALA ALA D . n 
D 1 333 GLN 333 333 333 GLN GLN D . n 
D 1 334 ARG 334 334 334 ARG ARG D . n 
D 1 335 ASP 335 335 335 ASP ASP D . n 
D 1 336 PHE 336 336 336 PHE PHE D . n 
D 1 337 ALA 337 337 337 ALA ALA D . n 
D 1 338 LEU 338 338 338 LEU LEU D . n 
D 1 339 LYS 339 339 339 LYS LYS D . n 
D 1 340 HIS 340 340 340 HIS HIS D . n 
D 1 341 LEU 341 341 341 LEU LEU D . n 
D 1 342 PRO 342 342 342 PRO PRO D . n 
D 1 343 ASP 343 343 343 ASP ASP D . n 
D 1 344 ASP 344 344 344 ASP ASP D . n 
D 1 345 GLU 345 345 345 GLU GLU D . n 
D 1 346 LEU 346 346 346 LEU LEU D . n 
D 1 347 PHE 347 347 347 PHE PHE D . n 
D 1 348 LYS 348 348 348 LYS LYS D . n 
D 1 349 ILE 349 349 349 ILE ILE D . n 
D 1 350 VAL 350 350 350 VAL VAL D . n 
D 1 351 SER 351 351 351 SER SER D . n 
D 1 352 LEU 352 352 352 LEU LEU D . n 
D 1 353 CYS 353 353 353 CYS CYS D . n 
D 1 354 TYR 354 354 354 TYR TYR D . n 
D 1 355 GLU 355 355 355 GLU GLU D . n 
D 1 356 VAL 356 356 356 VAL VAL D . n 
D 1 357 ILE 357 357 357 ILE ILE D . n 
D 1 358 PRO 358 358 358 PRO PRO D . n 
D 1 359 GLU 359 359 359 GLU GLU D . n 
D 1 360 VAL 360 360 360 VAL VAL D . n 
D 1 361 LEU 361 361 361 LEU LEU D . n 
D 1 362 LYS 362 362 362 LYS LYS D . n 
D 1 363 LYS 363 363 363 LYS LYS D . n 
D 1 364 HIS 364 364 364 HIS HIS D . n 
D 1 365 GLY 365 365 365 GLY GLY D . n 
D 1 366 LYS 366 366 366 LYS LYS D . n 
D 1 367 ALA 367 367 367 ALA ALA D . n 
D 1 368 LYS 368 368 368 LYS LYS D . n 
D 1 369 ASN 369 369 369 ASN ASN D . n 
D 1 370 PRO 370 370 370 PRO PRO D . n 
D 1 371 TRP 371 371 371 TRP TRP D . n 
D 1 372 PRO 372 372 372 PRO PRO D . n 
D 1 373 ASN 373 373 373 ASN ASN D . n 
D 1 374 VAL 374 374 374 VAL VAL D . n 
D 1 375 ASP 375 375 375 ASP ASP D . n 
D 1 376 ALA 376 376 376 ALA ALA D . n 
D 1 377 HIS 377 377 377 HIS HIS D . n 
D 1 378 SER 378 378 378 SER SER D . n 
D 1 379 GLY 379 379 379 GLY GLY D . n 
D 1 380 VAL 380 380 380 VAL VAL D . n 
D 1 381 LEU 381 381 381 LEU LEU D . n 
D 1 382 LEU 382 382 382 LEU LEU D . n 
D 1 383 TRP 383 383 383 TRP TRP D . n 
D 1 384 HIS 384 384 384 HIS HIS D . n 
D 1 385 TYR 385 385 385 TYR TYR D . n 
D 1 386 GLY 386 386 386 GLY GLY D . n 
D 1 387 ILE 387 387 387 ILE ILE D . n 
D 1 388 ARG 388 388 388 ARG ARG D . n 
D 1 389 GLU 389 389 389 GLU GLU D . n 
D 1 390 TYR 390 390 390 TYR TYR D . n 
D 1 391 ASP 391 391 391 ASP ASP D . n 
D 1 392 PHE 392 392 392 PHE PHE D . n 
D 1 393 TYR 393 393 393 TYR TYR D . n 
D 1 394 THR 394 394 394 THR THR D . n 
D 1 395 VAL 395 395 395 VAL VAL D . n 
D 1 396 LEU 396 396 396 LEU LEU D . n 
D 1 397 PHE 397 397 397 PHE PHE D . n 
D 1 398 GLY 398 398 398 GLY GLY D . n 
D 1 399 VAL 399 399 399 VAL VAL D . n 
D 1 400 SER 400 400 400 SER SER D . n 
D 1 401 ARG 401 401 401 ARG ARG D . n 
D 1 402 ALA 402 402 402 ALA ALA D . n 
D 1 403 LEU 403 403 403 LEU LEU D . n 
D 1 404 GLY 404 404 404 GLY GLY D . n 
D 1 405 CYS 405 405 405 CYS CYS D . n 
D 1 406 THR 406 406 406 THR THR D . n 
D 1 407 ALA 407 407 407 ALA ALA D . n 
D 1 408 GLN 408 408 408 GLN GLN D . n 
D 1 409 ALA 409 409 409 ALA ALA D . n 
D 1 410 ILE 410 410 410 ILE ILE D . n 
D 1 411 LEU 411 411 411 LEU LEU D . n 
D 1 412 VAL 412 412 412 VAL VAL D . n 
D 1 413 ARG 413 413 413 ARG ARG D . n 
D 1 414 GLY 414 414 414 GLY GLY D . n 
D 1 415 TYR 415 415 415 TYR TYR D . n 
D 1 416 MET 416 416 416 MET MET D . n 
D 1 417 LEU 417 417 417 LEU LEU D . n 
D 1 418 PRO 418 418 418 PRO PRO D . n 
D 1 419 ILE 419 419 419 ILE ILE D . n 
D 1 420 GLU 420 420 420 GLU GLU D . n 
D 1 421 ARG 421 421 421 ARG ARG D . n 
D 1 422 PRO 422 422 422 PRO PRO D . n 
D 1 423 LYS 423 423 423 LYS LYS D . n 
D 1 424 SER 424 424 424 SER SER D . n 
D 1 425 ILE 425 425 425 ILE ILE D . n 
D 1 426 THR 426 426 426 THR THR D . n 
D 1 427 THR 427 427 427 THR THR D . n 
D 1 428 ARG 428 428 428 ARG ARG D . n 
D 1 429 TRP 429 429 429 TRP TRP D . n 
D 1 430 VAL 430 430 430 VAL VAL D . n 
D 1 431 LYS 431 431 431 LYS LYS D . n 
D 1 432 GLU 432 432 432 GLU GLU D . n 
D 1 433 VAL 433 433 433 VAL VAL D . n 
D 1 434 ALA 434 434 434 ALA ALA D . n 
D 1 435 GLU 435 435 435 GLU GLU D . n 
D 1 436 SER 436 436 436 SER SER D . n 
D 1 437 LEU 437 437 437 LEU LEU D . n 
D 1 438 PRO 438 438 438 PRO PRO D . n 
D 1 439 VAL 439 439 439 VAL VAL D . n 
D 1 440 ALA 440 440 440 ALA ALA D . n 
D 1 441 GLY 441 441 ?   ?   ?   D . n 
D 1 442 SER 442 442 ?   ?   ?   D . n 
D 1 443 LYS 443 443 ?   ?   ?   D . n 
D 1 444 LEU 444 444 ?   ?   ?   D . n 
D 1 445 ALA 445 445 ?   ?   ?   D . n 
D 1 446 ALA 446 446 ?   ?   ?   D . n 
D 1 447 ALA 447 447 ?   ?   ?   D . n 
D 1 448 LEU 448 448 ?   ?   ?   D . n 
D 1 449 GLU 449 449 ?   ?   ?   D . n 
E 1 1   MET 1   1   1   MET MET E . n 
E 1 2   LYS 2   2   2   LYS LYS E . n 
E 1 3   LEU 3   3   3   LEU LEU E . n 
E 1 4   LYS 4   4   4   LYS LYS E . n 
E 1 5   GLU 5   5   5   GLU GLU E . n 
E 1 6   ARG 6   6   6   ARG ARG E . n 
E 1 7   LEU 7   7   7   LEU LEU E . n 
E 1 8   ALA 8   8   8   ALA ALA E . n 
E 1 9   GLU 9   9   9   GLU GLU E . n 
E 1 10  LEU 10  10  10  LEU LEU E . n 
E 1 11  ILE 11  11  11  ILE ILE E . n 
E 1 12  PRO 12  12  12  PRO PRO E . n 
E 1 13  GLN 13  13  13  GLN GLN E . n 
E 1 14  TRP 14  14  14  TRP TRP E . n 
E 1 15  ARG 15  15  15  ARG ARG E . n 
E 1 16  ALA 16  16  16  ALA ALA E . n 
E 1 17  GLU 17  17  17  GLU GLU E . n 
E 1 18  VAL 18  18  18  VAL VAL E . n 
E 1 19  ALA 19  19  19  ALA ALA E . n 
E 1 20  GLU 20  20  20  GLU GLU E . n 
E 1 21  ILE 21  21  21  ILE ILE E . n 
E 1 22  ARG 22  22  22  ARG ARG E . n 
E 1 23  LYS 23  23  23  LYS LYS E . n 
E 1 24  LYS 24  24  24  LYS LYS E . n 
E 1 25  TYR 25  25  25  TYR TYR E . n 
E 1 26  GLY 26  26  26  GLY GLY E . n 
E 1 27  ASN 27  27  27  ASN ASN E . n 
E 1 28  ARG 28  28  28  ARG ARG E . n 
E 1 29  LYS 29  29  29  LYS LYS E . n 
E 1 30  THR 30  30  30  THR THR E . n 
E 1 31  MET 31  31  31  MET MET E . n 
E 1 32  ASP 32  32  32  ASP ASP E . n 
E 1 33  CYS 33  33  33  CYS CYS E . n 
E 1 34  THR 34  34  34  THR THR E . n 
E 1 35  ILE 35  35  35  ILE ILE E . n 
E 1 36  GLY 36  36  36  GLY GLY E . n 
E 1 37  HIS 37  37  37  HIS HIS E . n 
E 1 38  ALA 38  38  38  ALA ALA E . n 
E 1 39  TYR 39  39  39  TYR TYR E . n 
E 1 40  GLY 40  40  40  GLY GLY E . n 
E 1 41  GLY 41  41  41  GLY GLY E . n 
E 1 42  MET 42  42  42  MET MET E . n 
E 1 43  ARG 43  43  43  ARG ARG E . n 
E 1 44  GLY 44  44  44  GLY GLY E . n 
E 1 45  LEU 45  45  45  LEU LEU E . n 
E 1 46  LYS 46  46  46  LYS LYS E . n 
E 1 47  ALA 47  47  47  ALA ALA E . n 
E 1 48  LEU 48  48  48  LEU LEU E . n 
E 1 49  VAL 49  49  49  VAL VAL E . n 
E 1 50  CYS 50  50  50  CYS CYS E . n 
E 1 51  ASP 51  51  51  ASP ASP E . n 
E 1 52  THR 52  52  52  THR THR E . n 
E 1 53  SER 53  53  53  SER SER E . n 
E 1 54  GLU 54  54  54  GLU GLU E . n 
E 1 55  VAL 55  55  55  VAL VAL E . n 
E 1 56  PHE 56  56  56  PHE PHE E . n 
E 1 57  PRO 57  57  57  PRO PRO E . n 
E 1 58  ASP 58  58  58  ASP ASP E . n 
E 1 59  GLU 59  59  59  GLU GLU E . n 
E 1 60  GLY 60  60  60  GLY GLY E . n 
E 1 61  VAL 61  61  61  VAL VAL E . n 
E 1 62  LYS 62  62  62  LYS LYS E . n 
E 1 63  PHE 63  63  63  PHE PHE E . n 
E 1 64  ARG 64  64  64  ARG ARG E . n 
E 1 65  GLY 65  65  65  GLY GLY E . n 
E 1 66  TYR 66  66  66  TYR TYR E . n 
E 1 67  THR 67  67  67  THR THR E . n 
E 1 68  ILE 68  68  68  ILE ILE E . n 
E 1 69  PRO 69  69  69  PRO PRO E . n 
E 1 70  GLU 70  70  70  GLU GLU E . n 
E 1 71  LEU 71  71  71  LEU LEU E . n 
E 1 72  ARG 72  72  72  ARG ARG E . n 
E 1 73  GLU 73  73  73  GLU GLU E . n 
E 1 74  GLY 74  74  74  GLY GLY E . n 
E 1 75  PRO 75  75  75  PRO PRO E . n 
E 1 76  HIS 76  76  76  HIS HIS E . n 
E 1 77  LYS 77  77  77  LYS LYS E . n 
E 1 78  LEU 78  78  78  LEU LEU E . n 
E 1 79  PRO 79  79  79  PRO PRO E . n 
E 1 80  THR 80  80  80  THR THR E . n 
E 1 81  ALA 81  81  81  ALA ALA E . n 
E 1 82  GLU 82  82  82  GLU GLU E . n 
E 1 83  GLY 83  83  83  GLY GLY E . n 
E 1 84  GLY 84  84  84  GLY GLY E . n 
E 1 85  PHE 85  85  85  PHE PHE E . n 
E 1 86  GLU 86  86  86  GLU GLU E . n 
E 1 87  PRO 87  87  87  PRO PRO E . n 
E 1 88  LEU 88  88  88  LEU LEU E . n 
E 1 89  PRO 89  89  89  PRO PRO E . n 
E 1 90  GLU 90  90  90  GLU GLU E . n 
E 1 91  GLY 91  91  91  GLY GLY E . n 
E 1 92  LEU 92  92  92  LEU LEU E . n 
E 1 93  TRP 93  93  93  TRP TRP E . n 
E 1 94  TYR 94  94  94  TYR TYR E . n 
E 1 95  LEU 95  95  95  LEU LEU E . n 
E 1 96  LEU 96  96  96  LEU LEU E . n 
E 1 97  LEU 97  97  97  LEU LEU E . n 
E 1 98  THR 98  98  98  THR THR E . n 
E 1 99  GLY 99  99  99  GLY GLY E . n 
E 1 100 GLU 100 100 100 GLU GLU E . n 
E 1 101 LEU 101 101 101 LEU LEU E . n 
E 1 102 PRO 102 102 102 PRO PRO E . n 
E 1 103 THR 103 103 103 THR THR E . n 
E 1 104 GLU 104 104 104 GLU GLU E . n 
E 1 105 GLU 105 105 105 GLU GLU E . n 
E 1 106 ASP 106 106 106 ASP ASP E . n 
E 1 107 VAL 107 107 107 VAL VAL E . n 
E 1 108 LYS 108 108 108 LYS LYS E . n 
E 1 109 GLU 109 109 109 GLU GLU E . n 
E 1 110 ILE 110 110 110 ILE ILE E . n 
E 1 111 SER 111 111 111 SER SER E . n 
E 1 112 ALA 112 112 112 ALA ALA E . n 
E 1 113 GLU 113 113 113 GLU GLU E . n 
E 1 114 PHE 114 114 114 PHE PHE E . n 
E 1 115 THR 115 115 115 THR THR E . n 
E 1 116 LYS 116 116 116 LYS LYS E . n 
E 1 117 ARG 117 117 117 ARG ARG E . n 
E 1 118 MET 118 118 118 MET MET E . n 
E 1 119 GLN 119 119 119 GLN GLN E . n 
E 1 120 ASN 120 120 120 ASN ASN E . n 
E 1 121 VAL 121 121 121 VAL VAL E . n 
E 1 122 PRO 122 122 122 PRO PRO E . n 
E 1 123 GLN 123 123 123 GLN GLN E . n 
E 1 124 TYR 124 124 124 TYR TYR E . n 
E 1 125 VAL 125 125 125 VAL VAL E . n 
E 1 126 PHE 126 126 126 PHE PHE E . n 
E 1 127 ASP 127 127 127 ASP ASP E . n 
E 1 128 VAL 128 128 128 VAL VAL E . n 
E 1 129 LEU 129 129 129 LEU LEU E . n 
E 1 130 ARG 130 130 130 ARG ARG E . n 
E 1 131 ALA 131 131 131 ALA ALA E . n 
E 1 132 MET 132 132 132 MET MET E . n 
E 1 133 PRO 133 133 133 PRO PRO E . n 
E 1 134 VAL 134 134 134 VAL VAL E . n 
E 1 135 ASP 135 135 135 ASP ASP E . n 
E 1 136 THR 136 136 136 THR THR E . n 
E 1 137 HIS 137 137 137 HIS HIS E . n 
E 1 138 PRO 138 138 138 PRO PRO E . n 
E 1 139 MET 139 139 139 MET MET E . n 
E 1 140 THR 140 140 140 THR THR E . n 
E 1 141 MET 141 141 141 MET MET E . n 
E 1 142 PHE 142 142 142 PHE PHE E . n 
E 1 143 ALA 143 143 143 ALA ALA E . n 
E 1 144 ALA 144 144 144 ALA ALA E . n 
E 1 145 GLY 145 145 145 GLY GLY E . n 
E 1 146 ILE 146 146 146 ILE ILE E . n 
E 1 147 LEU 147 147 147 LEU LEU E . n 
E 1 148 ALA 148 148 148 ALA ALA E . n 
E 1 149 MET 149 149 149 MET MET E . n 
E 1 150 GLN 150 150 150 GLN GLN E . n 
E 1 151 ARG 151 151 151 ARG ARG E . n 
E 1 152 GLU 152 152 152 GLU GLU E . n 
E 1 153 SER 153 153 153 SER SER E . n 
E 1 154 VAL 154 154 154 VAL VAL E . n 
E 1 155 PHE 155 155 155 PHE PHE E . n 
E 1 156 ALA 156 156 156 ALA ALA E . n 
E 1 157 LYS 157 157 157 LYS LYS E . n 
E 1 158 ARG 158 158 158 ARG ARG E . n 
E 1 159 TYR 159 159 159 TYR TYR E . n 
E 1 160 GLU 160 160 160 GLU GLU E . n 
E 1 161 GLU 161 161 161 GLU GLU E . n 
E 1 162 GLY 162 162 162 GLY GLY E . n 
E 1 163 MET 163 163 163 MET MET E . n 
E 1 164 ARG 164 164 164 ARG ARG E . n 
E 1 165 ARG 165 165 165 ARG ARG E . n 
E 1 166 GLU 166 166 166 GLU GLU E . n 
E 1 167 GLU 167 167 167 GLU GLU E . n 
E 1 168 HIS 168 168 168 HIS HIS E . n 
E 1 169 TRP 169 169 169 TRP TRP E . n 
E 1 170 GLU 170 170 170 GLU GLU E . n 
E 1 171 ALA 171 171 171 ALA ALA E . n 
E 1 172 MET 172 172 172 MET MET E . n 
E 1 173 LEU 173 173 173 LEU LEU E . n 
E 1 174 GLU 174 174 174 GLU GLU E . n 
E 1 175 ASP 175 175 175 ASP ASP E . n 
E 1 176 SER 176 176 176 SER SER E . n 
E 1 177 LEU 177 177 177 LEU LEU E . n 
E 1 178 ASN 178 178 178 ASN ASN E . n 
E 1 179 MET 179 179 179 MET MET E . n 
E 1 180 LEU 180 180 180 LEU LEU E . n 
E 1 181 ALA 181 181 181 ALA ALA E . n 
E 1 182 ALA 182 182 182 ALA ALA E . n 
E 1 183 LEU 183 183 183 LEU LEU E . n 
E 1 184 PRO 184 184 184 PRO PRO E . n 
E 1 185 VAL 185 185 185 VAL VAL E . n 
E 1 186 ILE 186 186 186 ILE ILE E . n 
E 1 187 ALA 187 187 187 ALA ALA E . n 
E 1 188 ALA 188 188 188 ALA ALA E . n 
E 1 189 TYR 189 189 189 TYR TYR E . n 
E 1 190 ILE 190 190 190 ILE ILE E . n 
E 1 191 TYR 191 191 191 TYR TYR E . n 
E 1 192 ARG 192 192 192 ARG ARG E . n 
E 1 193 ARG 193 193 193 ARG ARG E . n 
E 1 194 LYS 194 194 194 LYS LYS E . n 
E 1 195 TYR 195 195 195 TYR TYR E . n 
E 1 196 LYS 196 196 196 LYS LYS E . n 
E 1 197 GLY 197 197 197 GLY GLY E . n 
E 1 198 ASP 198 198 198 ASP ASP E . n 
E 1 199 THR 199 199 199 THR THR E . n 
E 1 200 HIS 200 200 200 HIS HIS E . n 
E 1 201 ILE 201 201 201 ILE ILE E . n 
E 1 202 ALA 202 202 202 ALA ALA E . n 
E 1 203 PRO 203 203 203 PRO PRO E . n 
E 1 204 ASP 204 204 204 ASP ASP E . n 
E 1 205 PRO 205 205 205 PRO PRO E . n 
E 1 206 ASN 206 206 206 ASN ASN E . n 
E 1 207 LEU 207 207 207 LEU LEU E . n 
E 1 208 ASP 208 208 208 ASP ASP E . n 
E 1 209 TRP 209 209 209 TRP TRP E . n 
E 1 210 SER 210 210 210 SER SER E . n 
E 1 211 ALA 211 211 211 ALA ALA E . n 
E 1 212 ASN 212 212 212 ASN ASN E . n 
E 1 213 LEU 213 213 213 LEU LEU E . n 
E 1 214 ALA 214 214 214 ALA ALA E . n 
E 1 215 HIS 215 215 215 HIS HIS E . n 
E 1 216 MET 216 216 216 MET MET E . n 
E 1 217 MET 217 217 217 MET MET E . n 
E 1 218 GLY 218 218 218 GLY GLY E . n 
E 1 219 PHE 219 219 219 PHE PHE E . n 
E 1 220 ASP 220 220 220 ASP ASP E . n 
E 1 221 ASP 221 221 221 ASP ASP E . n 
E 1 222 PHE 222 222 222 PHE PHE E . n 
E 1 223 GLU 223 223 223 GLU GLU E . n 
E 1 224 VAL 224 224 224 VAL VAL E . n 
E 1 225 TYR 225 225 225 TYR TYR E . n 
E 1 226 GLU 226 226 226 GLU GLU E . n 
E 1 227 LEU 227 227 227 LEU LEU E . n 
E 1 228 PHE 228 228 228 PHE PHE E . n 
E 1 229 ARG 229 229 229 ARG ARG E . n 
E 1 230 LEU 230 230 230 LEU LEU E . n 
E 1 231 TYR 231 231 231 TYR TYR E . n 
E 1 232 MET 232 232 232 MET MET E . n 
E 1 233 PHE 233 233 233 PHE PHE E . n 
E 1 234 LEU 234 234 234 LEU LEU E . n 
E 1 235 HIS 235 235 235 HIS HIS E . n 
E 1 236 SER 236 236 236 SER SER E . n 
E 1 237 ASP 237 237 237 ASP ASP E . n 
E 1 238 HIS 238 238 238 HIS HIS E . n 
E 1 239 GLU 239 239 239 GLU GLU E . n 
E 1 240 GLY 240 240 240 GLY GLY E . n 
E 1 241 GLY 241 241 241 GLY GLY E . n 
E 1 242 ASN 242 242 242 ASN ASN E . n 
E 1 243 VAL 243 243 243 VAL VAL E . n 
E 1 244 SER 244 244 244 SER SER E . n 
E 1 245 ALA 245 245 245 ALA ALA E . n 
E 1 246 HIS 246 246 246 HIS HIS E . n 
E 1 247 THR 247 247 247 THR THR E . n 
E 1 248 ASN 248 248 248 ASN ASN E . n 
E 1 249 LEU 249 249 249 LEU LEU E . n 
E 1 250 LEU 250 250 250 LEU LEU E . n 
E 1 251 VAL 251 251 251 VAL VAL E . n 
E 1 252 ASN 252 252 252 ASN ASN E . n 
E 1 253 SER 253 253 253 SER SER E . n 
E 1 254 ALA 254 254 254 ALA ALA E . n 
E 1 255 TYR 255 255 255 TYR TYR E . n 
E 1 256 SER 256 256 256 SER SER E . n 
E 1 257 ASP 257 257 257 ASP ASP E . n 
E 1 258 ILE 258 258 258 ILE ILE E . n 
E 1 259 TYR 259 259 259 TYR TYR E . n 
E 1 260 ARG 260 260 260 ARG ARG E . n 
E 1 261 SER 261 261 261 SER SER E . n 
E 1 262 PHE 262 262 262 PHE PHE E . n 
E 1 263 SER 263 263 263 SER SER E . n 
E 1 264 ALA 264 264 264 ALA ALA E . n 
E 1 265 ALA 265 265 265 ALA ALA E . n 
E 1 266 MET 266 266 266 MET MET E . n 
E 1 267 ASN 267 267 267 ASN ASN E . n 
E 1 268 GLY 268 268 268 GLY GLY E . n 
E 1 269 LEU 269 269 269 LEU LEU E . n 
E 1 270 ALA 270 270 270 ALA ALA E . n 
E 1 271 GLY 271 271 271 GLY GLY E . n 
E 1 272 PRO 272 272 272 PRO PRO E . n 
E 1 273 LEU 273 273 273 LEU LEU E . n 
E 1 274 HIS 274 274 274 HIS HIS E . n 
E 1 275 GLY 275 275 275 GLY GLY E . n 
E 1 276 LEU 276 276 276 LEU LEU E . n 
E 1 277 ALA 277 277 277 ALA ALA E . n 
E 1 278 ASN 278 278 278 ASN ASN E . n 
E 1 279 GLN 279 279 279 GLN GLN E . n 
E 1 280 GLU 280 280 280 GLU GLU E . n 
E 1 281 VAL 281 281 281 VAL VAL E . n 
E 1 282 LEU 282 282 282 LEU LEU E . n 
E 1 283 ARG 283 283 283 ARG ARG E . n 
E 1 284 TRP 284 284 284 TRP TRP E . n 
E 1 285 ILE 285 285 285 ILE ILE E . n 
E 1 286 GLN 286 286 286 GLN GLN E . n 
E 1 287 MET 287 287 287 MET MET E . n 
E 1 288 LEU 288 288 288 LEU LEU E . n 
E 1 289 TYR 289 289 289 TYR TYR E . n 
E 1 290 LYS 290 290 290 LYS LYS E . n 
E 1 291 LYS 291 291 291 LYS LYS E . n 
E 1 292 PHE 292 292 292 PHE PHE E . n 
E 1 293 GLY 293 293 293 GLY GLY E . n 
E 1 294 GLY 294 294 294 GLY GLY E . n 
E 1 295 VAL 295 295 295 VAL VAL E . n 
E 1 296 PRO 296 296 296 PRO PRO E . n 
E 1 297 THR 297 297 297 THR THR E . n 
E 1 298 LYS 298 298 298 LYS LYS E . n 
E 1 299 GLU 299 299 299 GLU GLU E . n 
E 1 300 GLN 300 300 300 GLN GLN E . n 
E 1 301 LEU 301 301 301 LEU LEU E . n 
E 1 302 GLU 302 302 302 GLU GLU E . n 
E 1 303 ARG 303 303 303 ARG ARG E . n 
E 1 304 PHE 304 304 304 PHE PHE E . n 
E 1 305 ALA 305 305 305 ALA ALA E . n 
E 1 306 TRP 306 306 306 TRP TRP E . n 
E 1 307 ASP 307 307 307 ASP ASP E . n 
E 1 308 THR 308 308 308 THR THR E . n 
E 1 309 LEU 309 309 309 LEU LEU E . n 
E 1 310 ASN 310 310 310 ASN ASN E . n 
E 1 311 SER 311 311 311 SER SER E . n 
E 1 312 GLY 312 312 312 GLY GLY E . n 
E 1 313 GLN 313 313 313 GLN GLN E . n 
E 1 314 VAL 314 314 314 VAL VAL E . n 
E 1 315 ILE 315 315 315 ILE ILE E . n 
E 1 316 PRO 316 316 316 PRO PRO E . n 
E 1 317 GLY 317 317 317 GLY GLY E . n 
E 1 318 TYR 318 318 318 TYR TYR E . n 
E 1 319 GLY 319 319 319 GLY GLY E . n 
E 1 320 HIS 320 320 320 HIS HIS E . n 
E 1 321 ALA 321 321 321 ALA ALA E . n 
E 1 322 VAL 322 322 322 VAL VAL E . n 
E 1 323 LEU 323 323 323 LEU LEU E . n 
E 1 324 ARG 324 324 324 ARG ARG E . n 
E 1 325 VAL 325 325 325 VAL VAL E . n 
E 1 326 THR 326 326 326 THR THR E . n 
E 1 327 ASP 327 327 327 ASP ASP E . n 
E 1 328 PRO 328 328 328 PRO PRO E . n 
E 1 329 ARG 329 329 329 ARG ARG E . n 
E 1 330 TYR 330 330 330 TYR TYR E . n 
E 1 331 VAL 331 331 331 VAL VAL E . n 
E 1 332 ALA 332 332 332 ALA ALA E . n 
E 1 333 GLN 333 333 333 GLN GLN E . n 
E 1 334 ARG 334 334 334 ARG ARG E . n 
E 1 335 ASP 335 335 335 ASP ASP E . n 
E 1 336 PHE 336 336 336 PHE PHE E . n 
E 1 337 ALA 337 337 337 ALA ALA E . n 
E 1 338 LEU 338 338 338 LEU LEU E . n 
E 1 339 LYS 339 339 339 LYS LYS E . n 
E 1 340 HIS 340 340 340 HIS HIS E . n 
E 1 341 LEU 341 341 341 LEU LEU E . n 
E 1 342 PRO 342 342 342 PRO PRO E . n 
E 1 343 ASP 343 343 343 ASP ASP E . n 
E 1 344 ASP 344 344 344 ASP ASP E . n 
E 1 345 GLU 345 345 345 GLU GLU E . n 
E 1 346 LEU 346 346 346 LEU LEU E . n 
E 1 347 PHE 347 347 347 PHE PHE E . n 
E 1 348 LYS 348 348 348 LYS LYS E . n 
E 1 349 ILE 349 349 349 ILE ILE E . n 
E 1 350 VAL 350 350 350 VAL VAL E . n 
E 1 351 SER 351 351 351 SER SER E . n 
E 1 352 LEU 352 352 352 LEU LEU E . n 
E 1 353 CYS 353 353 353 CYS CYS E . n 
E 1 354 TYR 354 354 354 TYR TYR E . n 
E 1 355 GLU 355 355 355 GLU GLU E . n 
E 1 356 VAL 356 356 356 VAL VAL E . n 
E 1 357 ILE 357 357 357 ILE ILE E . n 
E 1 358 PRO 358 358 358 PRO PRO E . n 
E 1 359 GLU 359 359 359 GLU GLU E . n 
E 1 360 VAL 360 360 360 VAL VAL E . n 
E 1 361 LEU 361 361 361 LEU LEU E . n 
E 1 362 LYS 362 362 362 LYS LYS E . n 
E 1 363 LYS 363 363 363 LYS LYS E . n 
E 1 364 HIS 364 364 364 HIS HIS E . n 
E 1 365 GLY 365 365 365 GLY GLY E . n 
E 1 366 LYS 366 366 366 LYS LYS E . n 
E 1 367 ALA 367 367 367 ALA ALA E . n 
E 1 368 LYS 368 368 368 LYS LYS E . n 
E 1 369 ASN 369 369 369 ASN ASN E . n 
E 1 370 PRO 370 370 370 PRO PRO E . n 
E 1 371 TRP 371 371 371 TRP TRP E . n 
E 1 372 PRO 372 372 372 PRO PRO E . n 
E 1 373 ASN 373 373 373 ASN ASN E . n 
E 1 374 VAL 374 374 374 VAL VAL E . n 
E 1 375 ASP 375 375 375 ASP ASP E . n 
E 1 376 ALA 376 376 376 ALA ALA E . n 
E 1 377 HIS 377 377 377 HIS HIS E . n 
E 1 378 SER 378 378 378 SER SER E . n 
E 1 379 GLY 379 379 379 GLY GLY E . n 
E 1 380 VAL 380 380 380 VAL VAL E . n 
E 1 381 LEU 381 381 381 LEU LEU E . n 
E 1 382 LEU 382 382 382 LEU LEU E . n 
E 1 383 TRP 383 383 383 TRP TRP E . n 
E 1 384 HIS 384 384 384 HIS HIS E . n 
E 1 385 TYR 385 385 385 TYR TYR E . n 
E 1 386 GLY 386 386 386 GLY GLY E . n 
E 1 387 ILE 387 387 387 ILE ILE E . n 
E 1 388 ARG 388 388 388 ARG ARG E . n 
E 1 389 GLU 389 389 389 GLU GLU E . n 
E 1 390 TYR 390 390 390 TYR TYR E . n 
E 1 391 ASP 391 391 391 ASP ASP E . n 
E 1 392 PHE 392 392 392 PHE PHE E . n 
E 1 393 TYR 393 393 393 TYR TYR E . n 
E 1 394 THR 394 394 394 THR THR E . n 
E 1 395 VAL 395 395 395 VAL VAL E . n 
E 1 396 LEU 396 396 396 LEU LEU E . n 
E 1 397 PHE 397 397 397 PHE PHE E . n 
E 1 398 GLY 398 398 398 GLY GLY E . n 
E 1 399 VAL 399 399 399 VAL VAL E . n 
E 1 400 SER 400 400 400 SER SER E . n 
E 1 401 ARG 401 401 401 ARG ARG E . n 
E 1 402 ALA 402 402 402 ALA ALA E . n 
E 1 403 LEU 403 403 403 LEU LEU E . n 
E 1 404 GLY 404 404 404 GLY GLY E . n 
E 1 405 CYS 405 405 405 CYS CYS E . n 
E 1 406 THR 406 406 406 THR THR E . n 
E 1 407 ALA 407 407 407 ALA ALA E . n 
E 1 408 GLN 408 408 408 GLN GLN E . n 
E 1 409 ALA 409 409 409 ALA ALA E . n 
E 1 410 ILE 410 410 410 ILE ILE E . n 
E 1 411 LEU 411 411 411 LEU LEU E . n 
E 1 412 VAL 412 412 412 VAL VAL E . n 
E 1 413 ARG 413 413 413 ARG ARG E . n 
E 1 414 GLY 414 414 414 GLY GLY E . n 
E 1 415 TYR 415 415 415 TYR TYR E . n 
E 1 416 MET 416 416 416 MET MET E . n 
E 1 417 LEU 417 417 417 LEU LEU E . n 
E 1 418 PRO 418 418 418 PRO PRO E . n 
E 1 419 ILE 419 419 419 ILE ILE E . n 
E 1 420 GLU 420 420 420 GLU GLU E . n 
E 1 421 ARG 421 421 421 ARG ARG E . n 
E 1 422 PRO 422 422 422 PRO PRO E . n 
E 1 423 LYS 423 423 423 LYS LYS E . n 
E 1 424 SER 424 424 424 SER SER E . n 
E 1 425 ILE 425 425 425 ILE ILE E . n 
E 1 426 THR 426 426 426 THR THR E . n 
E 1 427 THR 427 427 427 THR THR E . n 
E 1 428 ARG 428 428 428 ARG ARG E . n 
E 1 429 TRP 429 429 429 TRP TRP E . n 
E 1 430 VAL 430 430 430 VAL VAL E . n 
E 1 431 LYS 431 431 431 LYS LYS E . n 
E 1 432 GLU 432 432 432 GLU GLU E . n 
E 1 433 VAL 433 433 433 VAL VAL E . n 
E 1 434 ALA 434 434 434 ALA ALA E . n 
E 1 435 GLU 435 435 435 GLU GLU E . n 
E 1 436 SER 436 436 436 SER SER E . n 
E 1 437 LEU 437 437 437 LEU LEU E . n 
E 1 438 PRO 438 438 438 PRO PRO E . n 
E 1 439 VAL 439 439 439 VAL VAL E . n 
E 1 440 ALA 440 440 440 ALA ALA E . n 
E 1 441 GLY 441 441 441 GLY GLY E . n 
E 1 442 SER 442 442 ?   ?   ?   E . n 
E 1 443 LYS 443 443 ?   ?   ?   E . n 
E 1 444 LEU 444 444 ?   ?   ?   E . n 
E 1 445 ALA 445 445 ?   ?   ?   E . n 
E 1 446 ALA 446 446 ?   ?   ?   E . n 
E 1 447 ALA 447 447 ?   ?   ?   E . n 
E 1 448 LEU 448 448 ?   ?   ?   E . n 
E 1 449 GLU 449 449 ?   ?   ?   E . n 
F 1 1   MET 1   1   1   MET MET F . n 
F 1 2   LYS 2   2   2   LYS LYS F . n 
F 1 3   LEU 3   3   3   LEU LEU F . n 
F 1 4   LYS 4   4   4   LYS LYS F . n 
F 1 5   GLU 5   5   5   GLU GLU F . n 
F 1 6   ARG 6   6   6   ARG ARG F . n 
F 1 7   LEU 7   7   7   LEU LEU F . n 
F 1 8   ALA 8   8   8   ALA ALA F . n 
F 1 9   GLU 9   9   9   GLU GLU F . n 
F 1 10  LEU 10  10  10  LEU LEU F . n 
F 1 11  ILE 11  11  11  ILE ILE F . n 
F 1 12  PRO 12  12  12  PRO PRO F . n 
F 1 13  GLN 13  13  13  GLN GLN F . n 
F 1 14  TRP 14  14  14  TRP TRP F . n 
F 1 15  ARG 15  15  15  ARG ARG F . n 
F 1 16  ALA 16  16  16  ALA ALA F . n 
F 1 17  GLU 17  17  17  GLU GLU F . n 
F 1 18  VAL 18  18  18  VAL VAL F . n 
F 1 19  ALA 19  19  19  ALA ALA F . n 
F 1 20  GLU 20  20  20  GLU GLU F . n 
F 1 21  ILE 21  21  21  ILE ILE F . n 
F 1 22  ARG 22  22  22  ARG ARG F . n 
F 1 23  LYS 23  23  23  LYS LYS F . n 
F 1 24  LYS 24  24  24  LYS LYS F . n 
F 1 25  TYR 25  25  25  TYR TYR F . n 
F 1 26  GLY 26  26  26  GLY GLY F . n 
F 1 27  ASN 27  27  27  ASN ASN F . n 
F 1 28  ARG 28  28  28  ARG ARG F . n 
F 1 29  LYS 29  29  29  LYS LYS F . n 
F 1 30  THR 30  30  30  THR THR F . n 
F 1 31  MET 31  31  31  MET MET F . n 
F 1 32  ASP 32  32  32  ASP ASP F . n 
F 1 33  CYS 33  33  33  CYS CYS F . n 
F 1 34  THR 34  34  34  THR THR F . n 
F 1 35  ILE 35  35  35  ILE ILE F . n 
F 1 36  GLY 36  36  36  GLY GLY F . n 
F 1 37  HIS 37  37  37  HIS HIS F . n 
F 1 38  ALA 38  38  38  ALA ALA F . n 
F 1 39  TYR 39  39  39  TYR TYR F . n 
F 1 40  GLY 40  40  40  GLY GLY F . n 
F 1 41  GLY 41  41  41  GLY GLY F . n 
F 1 42  MET 42  42  42  MET MET F . n 
F 1 43  ARG 43  43  43  ARG ARG F . n 
F 1 44  GLY 44  44  44  GLY GLY F . n 
F 1 45  LEU 45  45  45  LEU LEU F . n 
F 1 46  LYS 46  46  46  LYS LYS F . n 
F 1 47  ALA 47  47  47  ALA ALA F . n 
F 1 48  LEU 48  48  48  LEU LEU F . n 
F 1 49  VAL 49  49  49  VAL VAL F . n 
F 1 50  CYS 50  50  50  CYS CYS F . n 
F 1 51  ASP 51  51  51  ASP ASP F . n 
F 1 52  THR 52  52  52  THR THR F . n 
F 1 53  SER 53  53  53  SER SER F . n 
F 1 54  GLU 54  54  54  GLU GLU F . n 
F 1 55  VAL 55  55  55  VAL VAL F . n 
F 1 56  PHE 56  56  56  PHE PHE F . n 
F 1 57  PRO 57  57  57  PRO PRO F . n 
F 1 58  ASP 58  58  58  ASP ASP F . n 
F 1 59  GLU 59  59  59  GLU GLU F . n 
F 1 60  GLY 60  60  60  GLY GLY F . n 
F 1 61  VAL 61  61  61  VAL VAL F . n 
F 1 62  LYS 62  62  62  LYS LYS F . n 
F 1 63  PHE 63  63  63  PHE PHE F . n 
F 1 64  ARG 64  64  64  ARG ARG F . n 
F 1 65  GLY 65  65  65  GLY GLY F . n 
F 1 66  TYR 66  66  66  TYR TYR F . n 
F 1 67  THR 67  67  67  THR THR F . n 
F 1 68  ILE 68  68  68  ILE ILE F . n 
F 1 69  PRO 69  69  69  PRO PRO F . n 
F 1 70  GLU 70  70  70  GLU GLU F . n 
F 1 71  LEU 71  71  71  LEU LEU F . n 
F 1 72  ARG 72  72  72  ARG ARG F . n 
F 1 73  GLU 73  73  73  GLU GLU F . n 
F 1 74  GLY 74  74  74  GLY GLY F . n 
F 1 75  PRO 75  75  75  PRO PRO F . n 
F 1 76  HIS 76  76  76  HIS HIS F . n 
F 1 77  LYS 77  77  77  LYS LYS F . n 
F 1 78  LEU 78  78  78  LEU LEU F . n 
F 1 79  PRO 79  79  79  PRO PRO F . n 
F 1 80  THR 80  80  80  THR THR F . n 
F 1 81  ALA 81  81  81  ALA ALA F . n 
F 1 82  GLU 82  82  82  GLU GLU F . n 
F 1 83  GLY 83  83  83  GLY GLY F . n 
F 1 84  GLY 84  84  84  GLY GLY F . n 
F 1 85  PHE 85  85  85  PHE PHE F . n 
F 1 86  GLU 86  86  86  GLU GLU F . n 
F 1 87  PRO 87  87  87  PRO PRO F . n 
F 1 88  LEU 88  88  88  LEU LEU F . n 
F 1 89  PRO 89  89  89  PRO PRO F . n 
F 1 90  GLU 90  90  90  GLU GLU F . n 
F 1 91  GLY 91  91  91  GLY GLY F . n 
F 1 92  LEU 92  92  92  LEU LEU F . n 
F 1 93  TRP 93  93  93  TRP TRP F . n 
F 1 94  TYR 94  94  94  TYR TYR F . n 
F 1 95  LEU 95  95  95  LEU LEU F . n 
F 1 96  LEU 96  96  96  LEU LEU F . n 
F 1 97  LEU 97  97  97  LEU LEU F . n 
F 1 98  THR 98  98  98  THR THR F . n 
F 1 99  GLY 99  99  99  GLY GLY F . n 
F 1 100 GLU 100 100 100 GLU GLU F . n 
F 1 101 LEU 101 101 101 LEU LEU F . n 
F 1 102 PRO 102 102 102 PRO PRO F . n 
F 1 103 THR 103 103 103 THR THR F . n 
F 1 104 GLU 104 104 104 GLU GLU F . n 
F 1 105 GLU 105 105 105 GLU GLU F . n 
F 1 106 ASP 106 106 106 ASP ASP F . n 
F 1 107 VAL 107 107 107 VAL VAL F . n 
F 1 108 LYS 108 108 108 LYS LYS F . n 
F 1 109 GLU 109 109 109 GLU GLU F . n 
F 1 110 ILE 110 110 110 ILE ILE F . n 
F 1 111 SER 111 111 111 SER SER F . n 
F 1 112 ALA 112 112 112 ALA ALA F . n 
F 1 113 GLU 113 113 113 GLU GLU F . n 
F 1 114 PHE 114 114 114 PHE PHE F . n 
F 1 115 THR 115 115 115 THR THR F . n 
F 1 116 LYS 116 116 116 LYS LYS F . n 
F 1 117 ARG 117 117 117 ARG ARG F . n 
F 1 118 MET 118 118 118 MET MET F . n 
F 1 119 GLN 119 119 119 GLN GLN F . n 
F 1 120 ASN 120 120 120 ASN ASN F . n 
F 1 121 VAL 121 121 121 VAL VAL F . n 
F 1 122 PRO 122 122 122 PRO PRO F . n 
F 1 123 GLN 123 123 123 GLN GLN F . n 
F 1 124 TYR 124 124 124 TYR TYR F . n 
F 1 125 VAL 125 125 125 VAL VAL F . n 
F 1 126 PHE 126 126 126 PHE PHE F . n 
F 1 127 ASP 127 127 127 ASP ASP F . n 
F 1 128 VAL 128 128 128 VAL VAL F . n 
F 1 129 LEU 129 129 129 LEU LEU F . n 
F 1 130 ARG 130 130 130 ARG ARG F . n 
F 1 131 ALA 131 131 131 ALA ALA F . n 
F 1 132 MET 132 132 132 MET MET F . n 
F 1 133 PRO 133 133 133 PRO PRO F . n 
F 1 134 VAL 134 134 134 VAL VAL F . n 
F 1 135 ASP 135 135 135 ASP ASP F . n 
F 1 136 THR 136 136 136 THR THR F . n 
F 1 137 HIS 137 137 137 HIS HIS F . n 
F 1 138 PRO 138 138 138 PRO PRO F . n 
F 1 139 MET 139 139 139 MET MET F . n 
F 1 140 THR 140 140 140 THR THR F . n 
F 1 141 MET 141 141 141 MET MET F . n 
F 1 142 PHE 142 142 142 PHE PHE F . n 
F 1 143 ALA 143 143 143 ALA ALA F . n 
F 1 144 ALA 144 144 144 ALA ALA F . n 
F 1 145 GLY 145 145 145 GLY GLY F . n 
F 1 146 ILE 146 146 146 ILE ILE F . n 
F 1 147 LEU 147 147 147 LEU LEU F . n 
F 1 148 ALA 148 148 148 ALA ALA F . n 
F 1 149 MET 149 149 149 MET MET F . n 
F 1 150 GLN 150 150 150 GLN GLN F . n 
F 1 151 ARG 151 151 151 ARG ARG F . n 
F 1 152 GLU 152 152 152 GLU GLU F . n 
F 1 153 SER 153 153 153 SER SER F . n 
F 1 154 VAL 154 154 154 VAL VAL F . n 
F 1 155 PHE 155 155 155 PHE PHE F . n 
F 1 156 ALA 156 156 156 ALA ALA F . n 
F 1 157 LYS 157 157 157 LYS LYS F . n 
F 1 158 ARG 158 158 158 ARG ARG F . n 
F 1 159 TYR 159 159 159 TYR TYR F . n 
F 1 160 GLU 160 160 160 GLU GLU F . n 
F 1 161 GLU 161 161 161 GLU GLU F . n 
F 1 162 GLY 162 162 162 GLY GLY F . n 
F 1 163 MET 163 163 163 MET MET F . n 
F 1 164 ARG 164 164 164 ARG ARG F . n 
F 1 165 ARG 165 165 165 ARG ARG F . n 
F 1 166 GLU 166 166 166 GLU GLU F . n 
F 1 167 GLU 167 167 167 GLU GLU F . n 
F 1 168 HIS 168 168 168 HIS HIS F . n 
F 1 169 TRP 169 169 169 TRP TRP F . n 
F 1 170 GLU 170 170 170 GLU GLU F . n 
F 1 171 ALA 171 171 171 ALA ALA F . n 
F 1 172 MET 172 172 172 MET MET F . n 
F 1 173 LEU 173 173 173 LEU LEU F . n 
F 1 174 GLU 174 174 174 GLU GLU F . n 
F 1 175 ASP 175 175 175 ASP ASP F . n 
F 1 176 SER 176 176 176 SER SER F . n 
F 1 177 LEU 177 177 177 LEU LEU F . n 
F 1 178 ASN 178 178 178 ASN ASN F . n 
F 1 179 MET 179 179 179 MET MET F . n 
F 1 180 LEU 180 180 180 LEU LEU F . n 
F 1 181 ALA 181 181 181 ALA ALA F . n 
F 1 182 ALA 182 182 182 ALA ALA F . n 
F 1 183 LEU 183 183 183 LEU LEU F . n 
F 1 184 PRO 184 184 184 PRO PRO F . n 
F 1 185 VAL 185 185 185 VAL VAL F . n 
F 1 186 ILE 186 186 186 ILE ILE F . n 
F 1 187 ALA 187 187 187 ALA ALA F . n 
F 1 188 ALA 188 188 188 ALA ALA F . n 
F 1 189 TYR 189 189 189 TYR TYR F . n 
F 1 190 ILE 190 190 190 ILE ILE F . n 
F 1 191 TYR 191 191 191 TYR TYR F . n 
F 1 192 ARG 192 192 192 ARG ARG F . n 
F 1 193 ARG 193 193 193 ARG ARG F . n 
F 1 194 LYS 194 194 194 LYS LYS F . n 
F 1 195 TYR 195 195 195 TYR TYR F . n 
F 1 196 LYS 196 196 196 LYS LYS F . n 
F 1 197 GLY 197 197 197 GLY GLY F . n 
F 1 198 ASP 198 198 198 ASP ASP F . n 
F 1 199 THR 199 199 199 THR THR F . n 
F 1 200 HIS 200 200 200 HIS HIS F . n 
F 1 201 ILE 201 201 201 ILE ILE F . n 
F 1 202 ALA 202 202 202 ALA ALA F . n 
F 1 203 PRO 203 203 203 PRO PRO F . n 
F 1 204 ASP 204 204 204 ASP ASP F . n 
F 1 205 PRO 205 205 205 PRO PRO F . n 
F 1 206 ASN 206 206 206 ASN ASN F . n 
F 1 207 LEU 207 207 207 LEU LEU F . n 
F 1 208 ASP 208 208 208 ASP ASP F . n 
F 1 209 TRP 209 209 209 TRP TRP F . n 
F 1 210 SER 210 210 210 SER SER F . n 
F 1 211 ALA 211 211 211 ALA ALA F . n 
F 1 212 ASN 212 212 212 ASN ASN F . n 
F 1 213 LEU 213 213 213 LEU LEU F . n 
F 1 214 ALA 214 214 214 ALA ALA F . n 
F 1 215 HIS 215 215 215 HIS HIS F . n 
F 1 216 MET 216 216 216 MET MET F . n 
F 1 217 MET 217 217 217 MET MET F . n 
F 1 218 GLY 218 218 218 GLY GLY F . n 
F 1 219 PHE 219 219 219 PHE PHE F . n 
F 1 220 ASP 220 220 220 ASP ASP F . n 
F 1 221 ASP 221 221 221 ASP ASP F . n 
F 1 222 PHE 222 222 222 PHE PHE F . n 
F 1 223 GLU 223 223 223 GLU GLU F . n 
F 1 224 VAL 224 224 224 VAL VAL F . n 
F 1 225 TYR 225 225 225 TYR TYR F . n 
F 1 226 GLU 226 226 226 GLU GLU F . n 
F 1 227 LEU 227 227 227 LEU LEU F . n 
F 1 228 PHE 228 228 228 PHE PHE F . n 
F 1 229 ARG 229 229 229 ARG ARG F . n 
F 1 230 LEU 230 230 230 LEU LEU F . n 
F 1 231 TYR 231 231 231 TYR TYR F . n 
F 1 232 MET 232 232 232 MET MET F . n 
F 1 233 PHE 233 233 233 PHE PHE F . n 
F 1 234 LEU 234 234 234 LEU LEU F . n 
F 1 235 HIS 235 235 235 HIS HIS F . n 
F 1 236 SER 236 236 236 SER SER F . n 
F 1 237 ASP 237 237 237 ASP ASP F . n 
F 1 238 HIS 238 238 238 HIS HIS F . n 
F 1 239 GLU 239 239 239 GLU GLU F . n 
F 1 240 GLY 240 240 240 GLY GLY F . n 
F 1 241 GLY 241 241 241 GLY GLY F . n 
F 1 242 ASN 242 242 242 ASN ASN F . n 
F 1 243 VAL 243 243 243 VAL VAL F . n 
F 1 244 SER 244 244 244 SER SER F . n 
F 1 245 ALA 245 245 245 ALA ALA F . n 
F 1 246 HIS 246 246 246 HIS HIS F . n 
F 1 247 THR 247 247 247 THR THR F . n 
F 1 248 ASN 248 248 248 ASN ASN F . n 
F 1 249 LEU 249 249 249 LEU LEU F . n 
F 1 250 LEU 250 250 250 LEU LEU F . n 
F 1 251 VAL 251 251 251 VAL VAL F . n 
F 1 252 ASN 252 252 252 ASN ASN F . n 
F 1 253 SER 253 253 253 SER SER F . n 
F 1 254 ALA 254 254 254 ALA ALA F . n 
F 1 255 TYR 255 255 255 TYR TYR F . n 
F 1 256 SER 256 256 256 SER SER F . n 
F 1 257 ASP 257 257 257 ASP ASP F . n 
F 1 258 ILE 258 258 258 ILE ILE F . n 
F 1 259 TYR 259 259 259 TYR TYR F . n 
F 1 260 ARG 260 260 260 ARG ARG F . n 
F 1 261 SER 261 261 261 SER SER F . n 
F 1 262 PHE 262 262 262 PHE PHE F . n 
F 1 263 SER 263 263 263 SER SER F . n 
F 1 264 ALA 264 264 264 ALA ALA F . n 
F 1 265 ALA 265 265 265 ALA ALA F . n 
F 1 266 MET 266 266 266 MET MET F . n 
F 1 267 ASN 267 267 267 ASN ASN F . n 
F 1 268 GLY 268 268 268 GLY GLY F . n 
F 1 269 LEU 269 269 269 LEU LEU F . n 
F 1 270 ALA 270 270 270 ALA ALA F . n 
F 1 271 GLY 271 271 271 GLY GLY F . n 
F 1 272 PRO 272 272 272 PRO PRO F . n 
F 1 273 LEU 273 273 273 LEU LEU F . n 
F 1 274 HIS 274 274 274 HIS HIS F . n 
F 1 275 GLY 275 275 275 GLY GLY F . n 
F 1 276 LEU 276 276 276 LEU LEU F . n 
F 1 277 ALA 277 277 277 ALA ALA F . n 
F 1 278 ASN 278 278 278 ASN ASN F . n 
F 1 279 GLN 279 279 279 GLN GLN F . n 
F 1 280 GLU 280 280 280 GLU GLU F . n 
F 1 281 VAL 281 281 281 VAL VAL F . n 
F 1 282 LEU 282 282 282 LEU LEU F . n 
F 1 283 ARG 283 283 283 ARG ARG F . n 
F 1 284 TRP 284 284 284 TRP TRP F . n 
F 1 285 ILE 285 285 285 ILE ILE F . n 
F 1 286 GLN 286 286 286 GLN GLN F . n 
F 1 287 MET 287 287 287 MET MET F . n 
F 1 288 LEU 288 288 288 LEU LEU F . n 
F 1 289 TYR 289 289 289 TYR TYR F . n 
F 1 290 LYS 290 290 290 LYS LYS F . n 
F 1 291 LYS 291 291 291 LYS LYS F . n 
F 1 292 PHE 292 292 292 PHE PHE F . n 
F 1 293 GLY 293 293 293 GLY GLY F . n 
F 1 294 GLY 294 294 294 GLY GLY F . n 
F 1 295 VAL 295 295 295 VAL VAL F . n 
F 1 296 PRO 296 296 296 PRO PRO F . n 
F 1 297 THR 297 297 297 THR THR F . n 
F 1 298 LYS 298 298 298 LYS LYS F . n 
F 1 299 GLU 299 299 299 GLU GLU F . n 
F 1 300 GLN 300 300 300 GLN GLN F . n 
F 1 301 LEU 301 301 301 LEU LEU F . n 
F 1 302 GLU 302 302 302 GLU GLU F . n 
F 1 303 ARG 303 303 303 ARG ARG F . n 
F 1 304 PHE 304 304 304 PHE PHE F . n 
F 1 305 ALA 305 305 305 ALA ALA F . n 
F 1 306 TRP 306 306 306 TRP TRP F . n 
F 1 307 ASP 307 307 307 ASP ASP F . n 
F 1 308 THR 308 308 308 THR THR F . n 
F 1 309 LEU 309 309 309 LEU LEU F . n 
F 1 310 ASN 310 310 310 ASN ASN F . n 
F 1 311 SER 311 311 311 SER SER F . n 
F 1 312 GLY 312 312 312 GLY GLY F . n 
F 1 313 GLN 313 313 313 GLN GLN F . n 
F 1 314 VAL 314 314 314 VAL VAL F . n 
F 1 315 ILE 315 315 315 ILE ILE F . n 
F 1 316 PRO 316 316 316 PRO PRO F . n 
F 1 317 GLY 317 317 317 GLY GLY F . n 
F 1 318 TYR 318 318 318 TYR TYR F . n 
F 1 319 GLY 319 319 319 GLY GLY F . n 
F 1 320 HIS 320 320 320 HIS HIS F . n 
F 1 321 ALA 321 321 321 ALA ALA F . n 
F 1 322 VAL 322 322 322 VAL VAL F . n 
F 1 323 LEU 323 323 323 LEU LEU F . n 
F 1 324 ARG 324 324 324 ARG ARG F . n 
F 1 325 VAL 325 325 325 VAL VAL F . n 
F 1 326 THR 326 326 326 THR THR F . n 
F 1 327 ASP 327 327 327 ASP ASP F . n 
F 1 328 PRO 328 328 328 PRO PRO F . n 
F 1 329 ARG 329 329 329 ARG ARG F . n 
F 1 330 TYR 330 330 330 TYR TYR F . n 
F 1 331 VAL 331 331 331 VAL VAL F . n 
F 1 332 ALA 332 332 332 ALA ALA F . n 
F 1 333 GLN 333 333 333 GLN GLN F . n 
F 1 334 ARG 334 334 334 ARG ARG F . n 
F 1 335 ASP 335 335 335 ASP ASP F . n 
F 1 336 PHE 336 336 336 PHE PHE F . n 
F 1 337 ALA 337 337 337 ALA ALA F . n 
F 1 338 LEU 338 338 338 LEU LEU F . n 
F 1 339 LYS 339 339 339 LYS LYS F . n 
F 1 340 HIS 340 340 340 HIS HIS F . n 
F 1 341 LEU 341 341 341 LEU LEU F . n 
F 1 342 PRO 342 342 342 PRO PRO F . n 
F 1 343 ASP 343 343 343 ASP ASP F . n 
F 1 344 ASP 344 344 344 ASP ASP F . n 
F 1 345 GLU 345 345 345 GLU GLU F . n 
F 1 346 LEU 346 346 346 LEU LEU F . n 
F 1 347 PHE 347 347 347 PHE PHE F . n 
F 1 348 LYS 348 348 348 LYS LYS F . n 
F 1 349 ILE 349 349 349 ILE ILE F . n 
F 1 350 VAL 350 350 350 VAL VAL F . n 
F 1 351 SER 351 351 351 SER SER F . n 
F 1 352 LEU 352 352 352 LEU LEU F . n 
F 1 353 CYS 353 353 353 CYS CYS F . n 
F 1 354 TYR 354 354 354 TYR TYR F . n 
F 1 355 GLU 355 355 355 GLU GLU F . n 
F 1 356 VAL 356 356 356 VAL VAL F . n 
F 1 357 ILE 357 357 357 ILE ILE F . n 
F 1 358 PRO 358 358 358 PRO PRO F . n 
F 1 359 GLU 359 359 359 GLU GLU F . n 
F 1 360 VAL 360 360 360 VAL VAL F . n 
F 1 361 LEU 361 361 361 LEU LEU F . n 
F 1 362 LYS 362 362 362 LYS LYS F . n 
F 1 363 LYS 363 363 363 LYS LYS F . n 
F 1 364 HIS 364 364 364 HIS HIS F . n 
F 1 365 GLY 365 365 365 GLY GLY F . n 
F 1 366 LYS 366 366 366 LYS LYS F . n 
F 1 367 ALA 367 367 367 ALA ALA F . n 
F 1 368 LYS 368 368 368 LYS LYS F . n 
F 1 369 ASN 369 369 369 ASN ASN F . n 
F 1 370 PRO 370 370 370 PRO PRO F . n 
F 1 371 TRP 371 371 371 TRP TRP F . n 
F 1 372 PRO 372 372 372 PRO PRO F . n 
F 1 373 ASN 373 373 373 ASN ASN F . n 
F 1 374 VAL 374 374 374 VAL VAL F . n 
F 1 375 ASP 375 375 375 ASP ASP F . n 
F 1 376 ALA 376 376 376 ALA ALA F . n 
F 1 377 HIS 377 377 377 HIS HIS F . n 
F 1 378 SER 378 378 378 SER SER F . n 
F 1 379 GLY 379 379 379 GLY GLY F . n 
F 1 380 VAL 380 380 380 VAL VAL F . n 
F 1 381 LEU 381 381 381 LEU LEU F . n 
F 1 382 LEU 382 382 382 LEU LEU F . n 
F 1 383 TRP 383 383 383 TRP TRP F . n 
F 1 384 HIS 384 384 384 HIS HIS F . n 
F 1 385 TYR 385 385 385 TYR TYR F . n 
F 1 386 GLY 386 386 386 GLY GLY F . n 
F 1 387 ILE 387 387 387 ILE ILE F . n 
F 1 388 ARG 388 388 388 ARG ARG F . n 
F 1 389 GLU 389 389 389 GLU GLU F . n 
F 1 390 TYR 390 390 390 TYR TYR F . n 
F 1 391 ASP 391 391 391 ASP ASP F . n 
F 1 392 PHE 392 392 392 PHE PHE F . n 
F 1 393 TYR 393 393 393 TYR TYR F . n 
F 1 394 THR 394 394 394 THR THR F . n 
F 1 395 VAL 395 395 395 VAL VAL F . n 
F 1 396 LEU 396 396 396 LEU LEU F . n 
F 1 397 PHE 397 397 397 PHE PHE F . n 
F 1 398 GLY 398 398 398 GLY GLY F . n 
F 1 399 VAL 399 399 399 VAL VAL F . n 
F 1 400 SER 400 400 400 SER SER F . n 
F 1 401 ARG 401 401 401 ARG ARG F . n 
F 1 402 ALA 402 402 402 ALA ALA F . n 
F 1 403 LEU 403 403 403 LEU LEU F . n 
F 1 404 GLY 404 404 404 GLY GLY F . n 
F 1 405 CYS 405 405 405 CYS CYS F . n 
F 1 406 THR 406 406 406 THR THR F . n 
F 1 407 ALA 407 407 407 ALA ALA F . n 
F 1 408 GLN 408 408 408 GLN GLN F . n 
F 1 409 ALA 409 409 409 ALA ALA F . n 
F 1 410 ILE 410 410 410 ILE ILE F . n 
F 1 411 LEU 411 411 411 LEU LEU F . n 
F 1 412 VAL 412 412 412 VAL VAL F . n 
F 1 413 ARG 413 413 413 ARG ARG F . n 
F 1 414 GLY 414 414 414 GLY GLY F . n 
F 1 415 TYR 415 415 415 TYR TYR F . n 
F 1 416 MET 416 416 416 MET MET F . n 
F 1 417 LEU 417 417 417 LEU LEU F . n 
F 1 418 PRO 418 418 418 PRO PRO F . n 
F 1 419 ILE 419 419 419 ILE ILE F . n 
F 1 420 GLU 420 420 420 GLU GLU F . n 
F 1 421 ARG 421 421 421 ARG ARG F . n 
F 1 422 PRO 422 422 422 PRO PRO F . n 
F 1 423 LYS 423 423 423 LYS LYS F . n 
F 1 424 SER 424 424 424 SER SER F . n 
F 1 425 ILE 425 425 425 ILE ILE F . n 
F 1 426 THR 426 426 426 THR THR F . n 
F 1 427 THR 427 427 427 THR THR F . n 
F 1 428 ARG 428 428 428 ARG ARG F . n 
F 1 429 TRP 429 429 429 TRP TRP F . n 
F 1 430 VAL 430 430 430 VAL VAL F . n 
F 1 431 LYS 431 431 431 LYS LYS F . n 
F 1 432 GLU 432 432 432 GLU GLU F . n 
F 1 433 VAL 433 433 433 VAL VAL F . n 
F 1 434 ALA 434 434 434 ALA ALA F . n 
F 1 435 GLU 435 435 435 GLU GLU F . n 
F 1 436 SER 436 436 436 SER SER F . n 
F 1 437 LEU 437 437 437 LEU LEU F . n 
F 1 438 PRO 438 438 438 PRO PRO F . n 
F 1 439 VAL 439 439 439 VAL VAL F . n 
F 1 440 ALA 440 440 440 ALA ALA F . n 
F 1 441 GLY 441 441 441 GLY GLY F . n 
F 1 442 SER 442 442 ?   ?   ?   F . n 
F 1 443 LYS 443 443 ?   ?   ?   F . n 
F 1 444 LEU 444 444 ?   ?   ?   F . n 
F 1 445 ALA 445 445 ?   ?   ?   F . n 
F 1 446 ALA 446 446 ?   ?   ?   F . n 
F 1 447 ALA 447 447 ?   ?   ?   F . n 
F 1 448 LEU 448 448 ?   ?   ?   F . n 
F 1 449 GLU 449 449 ?   ?   ?   F . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ACO ? ? ACO ? ? 'SUBJECT OF INVESTIGATION' ? 
2 COA ? ? COA ? ? 'SUBJECT OF INVESTIGATION' ? 
3 OAA ? ? OAA ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 2 OAA 1   501 503 OAA OAA A . 
H 3 ACO 1   502 504 ACO ACO A . 
I 2 OAA 1   501 501 OAA OAA B . 
J 2 OAA 1   501 501 OAA OAA D . 
K 4 COA 1   502 502 COA COA D . 
L 2 OAA 1   501 501 OAA OAA E . 
M 2 OAA 1   501 505 OAA OAA F . 
N 3 ACO 1   502 506 ACO ACO F . 
O 5 HOH 1   601 675 HOH HOH A . 
O 5 HOH 2   602 211 HOH HOH A . 
O 5 HOH 3   603 262 HOH HOH A . 
O 5 HOH 4   604 760 HOH HOH A . 
O 5 HOH 5   605 372 HOH HOH A . 
O 5 HOH 6   606 487 HOH HOH A . 
O 5 HOH 7   607 466 HOH HOH A . 
O 5 HOH 8   608 689 HOH HOH A . 
O 5 HOH 9   609 845 HOH HOH A . 
O 5 HOH 10  610 491 HOH HOH A . 
O 5 HOH 11  611 149 HOH HOH A . 
O 5 HOH 12  612 458 HOH HOH A . 
O 5 HOH 13  613 764 HOH HOH A . 
O 5 HOH 14  614 217 HOH HOH A . 
O 5 HOH 15  615 124 HOH HOH A . 
O 5 HOH 16  616 37  HOH HOH A . 
O 5 HOH 17  617 315 HOH HOH A . 
O 5 HOH 18  618 750 HOH HOH A . 
O 5 HOH 19  619 290 HOH HOH A . 
O 5 HOH 20  620 289 HOH HOH A . 
O 5 HOH 21  621 545 HOH HOH A . 
O 5 HOH 22  622 20  HOH HOH A . 
O 5 HOH 23  623 296 HOH HOH A . 
O 5 HOH 24  624 267 HOH HOH A . 
O 5 HOH 25  625 309 HOH HOH A . 
O 5 HOH 26  626 84  HOH HOH A . 
O 5 HOH 27  627 255 HOH HOH A . 
O 5 HOH 28  628 424 HOH HOH A . 
O 5 HOH 29  629 814 HOH HOH A . 
O 5 HOH 30  630 767 HOH HOH A . 
O 5 HOH 31  631 638 HOH HOH A . 
O 5 HOH 32  632 319 HOH HOH A . 
O 5 HOH 33  633 203 HOH HOH A . 
O 5 HOH 34  634 125 HOH HOH A . 
O 5 HOH 35  635 687 HOH HOH A . 
O 5 HOH 36  636 843 HOH HOH A . 
O 5 HOH 37  637 361 HOH HOH A . 
O 5 HOH 38  638 335 HOH HOH A . 
O 5 HOH 39  639 779 HOH HOH A . 
O 5 HOH 40  640 308 HOH HOH A . 
O 5 HOH 41  641 869 HOH HOH A . 
O 5 HOH 42  642 784 HOH HOH A . 
O 5 HOH 43  643 824 HOH HOH A . 
O 5 HOH 44  644 83  HOH HOH A . 
O 5 HOH 45  645 806 HOH HOH A . 
O 5 HOH 46  646 825 HOH HOH A . 
O 5 HOH 47  647 575 HOH HOH A . 
O 5 HOH 48  648 35  HOH HOH A . 
O 5 HOH 49  649 259 HOH HOH A . 
O 5 HOH 50  650 177 HOH HOH A . 
O 5 HOH 51  651 853 HOH HOH A . 
O 5 HOH 52  652 140 HOH HOH A . 
O 5 HOH 53  653 696 HOH HOH A . 
O 5 HOH 54  654 142 HOH HOH A . 
O 5 HOH 55  655 827 HOH HOH A . 
O 5 HOH 56  656 79  HOH HOH A . 
O 5 HOH 57  657 108 HOH HOH A . 
O 5 HOH 58  658 647 HOH HOH A . 
O 5 HOH 59  659 598 HOH HOH A . 
O 5 HOH 60  660 718 HOH HOH A . 
O 5 HOH 61  661 205 HOH HOH A . 
O 5 HOH 62  662 373 HOH HOH A . 
O 5 HOH 63  663 56  HOH HOH A . 
O 5 HOH 64  664 344 HOH HOH A . 
O 5 HOH 65  665 29  HOH HOH A . 
O 5 HOH 66  666 581 HOH HOH A . 
O 5 HOH 67  667 89  HOH HOH A . 
O 5 HOH 68  668 698 HOH HOH A . 
O 5 HOH 69  669 128 HOH HOH A . 
O 5 HOH 70  670 612 HOH HOH A . 
O 5 HOH 71  671 310 HOH HOH A . 
O 5 HOH 72  672 820 HOH HOH A . 
O 5 HOH 73  673 801 HOH HOH A . 
O 5 HOH 74  674 86  HOH HOH A . 
O 5 HOH 75  675 81  HOH HOH A . 
O 5 HOH 76  676 725 HOH HOH A . 
O 5 HOH 77  677 14  HOH HOH A . 
O 5 HOH 78  678 770 HOH HOH A . 
O 5 HOH 79  679 608 HOH HOH A . 
O 5 HOH 80  680 327 HOH HOH A . 
O 5 HOH 81  681 420 HOH HOH A . 
O 5 HOH 82  682 789 HOH HOH A . 
O 5 HOH 83  683 774 HOH HOH A . 
O 5 HOH 84  684 719 HOH HOH A . 
O 5 HOH 85  685 406 HOH HOH A . 
O 5 HOH 86  686 553 HOH HOH A . 
O 5 HOH 87  687 798 HOH HOH A . 
O 5 HOH 88  688 742 HOH HOH A . 
O 5 HOH 89  689 448 HOH HOH A . 
O 5 HOH 90  690 858 HOH HOH A . 
O 5 HOH 91  691 857 HOH HOH A . 
O 5 HOH 92  692 730 HOH HOH A . 
O 5 HOH 93  693 678 HOH HOH A . 
O 5 HOH 94  694 409 HOH HOH A . 
O 5 HOH 95  695 795 HOH HOH A . 
O 5 HOH 96  696 663 HOH HOH A . 
O 5 HOH 97  697 712 HOH HOH A . 
O 5 HOH 98  698 546 HOH HOH A . 
O 5 HOH 99  699 523 HOH HOH A . 
O 5 HOH 100 700 230 HOH HOH A . 
O 5 HOH 101 701 295 HOH HOH A . 
O 5 HOH 102 702 716 HOH HOH A . 
O 5 HOH 103 703 570 HOH HOH A . 
O 5 HOH 104 704 813 HOH HOH A . 
O 5 HOH 105 705 264 HOH HOH A . 
O 5 HOH 106 706 874 HOH HOH A . 
O 5 HOH 107 707 148 HOH HOH A . 
O 5 HOH 108 708 218 HOH HOH A . 
O 5 HOH 109 709 882 HOH HOH A . 
O 5 HOH 110 710 855 HOH HOH A . 
O 5 HOH 111 711 468 HOH HOH A . 
O 5 HOH 112 712 884 HOH HOH A . 
O 5 HOH 113 713 668 HOH HOH A . 
O 5 HOH 114 714 276 HOH HOH A . 
O 5 HOH 115 715 822 HOH HOH A . 
O 5 HOH 116 716 732 HOH HOH A . 
O 5 HOH 117 717 879 HOH HOH A . 
P 5 HOH 1   601 525 HOH HOH B . 
P 5 HOH 2   602 714 HOH HOH B . 
P 5 HOH 3   603 741 HOH HOH B . 
P 5 HOH 4   604 25  HOH HOH B . 
P 5 HOH 5   605 132 HOH HOH B . 
P 5 HOH 6   606 200 HOH HOH B . 
P 5 HOH 7   607 269 HOH HOH B . 
P 5 HOH 8   608 873 HOH HOH B . 
P 5 HOH 9   609 588 HOH HOH B . 
P 5 HOH 10  610 861 HOH HOH B . 
P 5 HOH 11  611 283 HOH HOH B . 
P 5 HOH 12  612 157 HOH HOH B . 
P 5 HOH 13  613 58  HOH HOH B . 
P 5 HOH 14  614 318 HOH HOH B . 
P 5 HOH 15  615 644 HOH HOH B . 
P 5 HOH 16  616 550 HOH HOH B . 
P 5 HOH 17  617 507 HOH HOH B . 
P 5 HOH 18  618 127 HOH HOH B . 
P 5 HOH 19  619 589 HOH HOH B . 
P 5 HOH 20  620 736 HOH HOH B . 
P 5 HOH 21  621 121 HOH HOH B . 
P 5 HOH 22  622 311 HOH HOH B . 
P 5 HOH 23  623 166 HOH HOH B . 
P 5 HOH 24  624 665 HOH HOH B . 
P 5 HOH 25  625 88  HOH HOH B . 
P 5 HOH 26  626 184 HOH HOH B . 
P 5 HOH 27  627 336 HOH HOH B . 
P 5 HOH 28  628 735 HOH HOH B . 
P 5 HOH 29  629 453 HOH HOH B . 
P 5 HOH 30  630 451 HOH HOH B . 
P 5 HOH 31  631 61  HOH HOH B . 
P 5 HOH 32  632 771 HOH HOH B . 
P 5 HOH 33  633 509 HOH HOH B . 
P 5 HOH 34  634 439 HOH HOH B . 
P 5 HOH 35  635 859 HOH HOH B . 
P 5 HOH 36  636 502 HOH HOH B . 
P 5 HOH 37  637 300 HOH HOH B . 
P 5 HOH 38  638 629 HOH HOH B . 
P 5 HOH 39  639 416 HOH HOH B . 
P 5 HOH 40  640 776 HOH HOH B . 
P 5 HOH 41  641 170 HOH HOH B . 
P 5 HOH 42  642 388 HOH HOH B . 
P 5 HOH 43  643 654 HOH HOH B . 
P 5 HOH 44  644 683 HOH HOH B . 
P 5 HOH 45  645 430 HOH HOH B . 
P 5 HOH 46  646 815 HOH HOH B . 
P 5 HOH 47  647 47  HOH HOH B . 
P 5 HOH 48  648 791 HOH HOH B . 
P 5 HOH 49  649 234 HOH HOH B . 
P 5 HOH 50  650 216 HOH HOH B . 
P 5 HOH 51  651 585 HOH HOH B . 
P 5 HOH 52  652 342 HOH HOH B . 
P 5 HOH 53  653 246 HOH HOH B . 
P 5 HOH 54  654 569 HOH HOH B . 
P 5 HOH 55  655 160 HOH HOH B . 
P 5 HOH 56  656 367 HOH HOH B . 
P 5 HOH 57  657 87  HOH HOH B . 
P 5 HOH 58  658 783 HOH HOH B . 
P 5 HOH 59  659 59  HOH HOH B . 
P 5 HOH 60  660 516 HOH HOH B . 
P 5 HOH 61  661 727 HOH HOH B . 
P 5 HOH 62  662 106 HOH HOH B . 
P 5 HOH 63  663 233 HOH HOH B . 
P 5 HOH 64  664 220 HOH HOH B . 
P 5 HOH 65  665 182 HOH HOH B . 
P 5 HOH 66  666 57  HOH HOH B . 
P 5 HOH 67  667 365 HOH HOH B . 
P 5 HOH 68  668 870 HOH HOH B . 
P 5 HOH 69  669 413 HOH HOH B . 
P 5 HOH 70  670 729 HOH HOH B . 
P 5 HOH 71  671 461 HOH HOH B . 
P 5 HOH 72  672 605 HOH HOH B . 
P 5 HOH 73  673 384 HOH HOH B . 
P 5 HOH 74  674 701 HOH HOH B . 
P 5 HOH 75  675 208 HOH HOH B . 
P 5 HOH 76  676 370 HOH HOH B . 
P 5 HOH 77  677 480 HOH HOH B . 
P 5 HOH 78  678 862 HOH HOH B . 
P 5 HOH 79  679 559 HOH HOH B . 
P 5 HOH 80  680 122 HOH HOH B . 
P 5 HOH 81  681 436 HOH HOH B . 
P 5 HOH 82  682 688 HOH HOH B . 
P 5 HOH 83  683 284 HOH HOH B . 
P 5 HOH 84  684 819 HOH HOH B . 
P 5 HOH 85  685 55  HOH HOH B . 
P 5 HOH 86  686 692 HOH HOH B . 
P 5 HOH 87  687 724 HOH HOH B . 
P 5 HOH 88  688 482 HOH HOH B . 
P 5 HOH 89  689 700 HOH HOH B . 
P 5 HOH 90  690 249 HOH HOH B . 
P 5 HOH 91  691 800 HOH HOH B . 
P 5 HOH 92  692 375 HOH HOH B . 
P 5 HOH 93  693 794 HOH HOH B . 
P 5 HOH 94  694 260 HOH HOH B . 
P 5 HOH 95  695 434 HOH HOH B . 
P 5 HOH 96  696 401 HOH HOH B . 
P 5 HOH 97  697 619 HOH HOH B . 
P 5 HOH 98  698 671 HOH HOH B . 
P 5 HOH 99  699 350 HOH HOH B . 
P 5 HOH 100 700 91  HOH HOH B . 
P 5 HOH 101 701 834 HOH HOH B . 
P 5 HOH 102 702 186 HOH HOH B . 
P 5 HOH 103 703 485 HOH HOH B . 
P 5 HOH 104 704 279 HOH HOH B . 
P 5 HOH 105 705 109 HOH HOH B . 
P 5 HOH 106 706 339 HOH HOH B . 
P 5 HOH 107 707 497 HOH HOH B . 
P 5 HOH 108 708 43  HOH HOH B . 
P 5 HOH 109 709 666 HOH HOH B . 
P 5 HOH 110 710 699 HOH HOH B . 
P 5 HOH 111 711 871 HOH HOH B . 
P 5 HOH 112 712 49  HOH HOH B . 
P 5 HOH 113 713 583 HOH HOH B . 
P 5 HOH 114 714 323 HOH HOH B . 
P 5 HOH 115 715 769 HOH HOH B . 
P 5 HOH 116 716 720 HOH HOH B . 
P 5 HOH 117 717 396 HOH HOH B . 
P 5 HOH 118 718 614 HOH HOH B . 
P 5 HOH 119 719 584 HOH HOH B . 
P 5 HOH 120 720 715 HOH HOH B . 
P 5 HOH 121 721 758 HOH HOH B . 
P 5 HOH 122 722 607 HOH HOH B . 
P 5 HOH 123 723 543 HOH HOH B . 
P 5 HOH 124 724 765 HOH HOH B . 
P 5 HOH 125 725 391 HOH HOH B . 
P 5 HOH 126 726 600 HOH HOH B . 
P 5 HOH 127 727 386 HOH HOH B . 
P 5 HOH 128 728 398 HOH HOH B . 
P 5 HOH 129 729 77  HOH HOH B . 
P 5 HOH 130 730 676 HOH HOH B . 
P 5 HOH 131 731 551 HOH HOH B . 
P 5 HOH 132 732 886 HOH HOH B . 
P 5 HOH 133 733 829 HOH HOH B . 
P 5 HOH 134 734 532 HOH HOH B . 
P 5 HOH 135 735 721 HOH HOH B . 
P 5 HOH 136 736 892 HOH HOH B . 
P 5 HOH 137 737 5   HOH HOH B . 
P 5 HOH 138 738 856 HOH HOH B . 
P 5 HOH 139 739 172 HOH HOH B . 
P 5 HOH 140 740 555 HOH HOH B . 
P 5 HOH 141 741 891 HOH HOH B . 
P 5 HOH 142 742 887 HOH HOH B . 
P 5 HOH 143 743 212 HOH HOH B . 
P 5 HOH 144 744 519 HOH HOH B . 
P 5 HOH 145 745 863 HOH HOH B . 
P 5 HOH 146 746 885 HOH HOH B . 
P 5 HOH 147 747 639 HOH HOH B . 
P 5 HOH 148 748 554 HOH HOH B . 
P 5 HOH 149 749 883 HOH HOH B . 
P 5 HOH 150 750 889 HOH HOH B . 
P 5 HOH 151 751 816 HOH HOH B . 
P 5 HOH 152 752 669 HOH HOH B . 
Q 5 HOH 1   501 477 HOH HOH C . 
Q 5 HOH 2   502 236 HOH HOH C . 
Q 5 HOH 3   503 489 HOH HOH C . 
Q 5 HOH 4   504 437 HOH HOH C . 
Q 5 HOH 5   505 844 HOH HOH C . 
Q 5 HOH 6   506 465 HOH HOH C . 
Q 5 HOH 7   507 72  HOH HOH C . 
Q 5 HOH 8   508 129 HOH HOH C . 
Q 5 HOH 9   509 192 HOH HOH C . 
Q 5 HOH 10  510 593 HOH HOH C . 
Q 5 HOH 11  511 158 HOH HOH C . 
Q 5 HOH 12  512 187 HOH HOH C . 
Q 5 HOH 13  513 618 HOH HOH C . 
Q 5 HOH 14  514 227 HOH HOH C . 
Q 5 HOH 15  515 38  HOH HOH C . 
Q 5 HOH 16  516 195 HOH HOH C . 
Q 5 HOH 17  517 175 HOH HOH C . 
Q 5 HOH 18  518 655 HOH HOH C . 
Q 5 HOH 19  519 201 HOH HOH C . 
Q 5 HOH 20  520 431 HOH HOH C . 
Q 5 HOH 21  521 483 HOH HOH C . 
Q 5 HOH 22  522 389 HOH HOH C . 
Q 5 HOH 23  523 731 HOH HOH C . 
Q 5 HOH 24  524 399 HOH HOH C . 
Q 5 HOH 25  525 4   HOH HOH C . 
Q 5 HOH 26  526 872 HOH HOH C . 
Q 5 HOH 27  527 329 HOH HOH C . 
Q 5 HOH 28  528 99  HOH HOH C . 
Q 5 HOH 29  529 42  HOH HOH C . 
Q 5 HOH 30  530 297 HOH HOH C . 
Q 5 HOH 31  531 578 HOH HOH C . 
Q 5 HOH 32  532 82  HOH HOH C . 
Q 5 HOH 33  533 601 HOH HOH C . 
Q 5 HOH 34  534 790 HOH HOH C . 
Q 5 HOH 35  535 433 HOH HOH C . 
Q 5 HOH 36  536 444 HOH HOH C . 
Q 5 HOH 37  537 726 HOH HOH C . 
Q 5 HOH 38  538 582 HOH HOH C . 
Q 5 HOH 39  539 256 HOH HOH C . 
Q 5 HOH 40  540 785 HOH HOH C . 
Q 5 HOH 41  541 828 HOH HOH C . 
Q 5 HOH 42  542 739 HOH HOH C . 
Q 5 HOH 43  543 222 HOH HOH C . 
Q 5 HOH 44  544 830 HOH HOH C . 
Q 5 HOH 45  545 103 HOH HOH C . 
Q 5 HOH 46  546 219 HOH HOH C . 
Q 5 HOH 47  547 472 HOH HOH C . 
Q 5 HOH 48  548 40  HOH HOH C . 
Q 5 HOH 49  549 356 HOH HOH C . 
Q 5 HOH 50  550 410 HOH HOH C . 
Q 5 HOH 51  551 235 HOH HOH C . 
Q 5 HOH 52  552 254 HOH HOH C . 
Q 5 HOH 53  553 15  HOH HOH C . 
Q 5 HOH 54  554 478 HOH HOH C . 
Q 5 HOH 55  555 651 HOH HOH C . 
Q 5 HOH 56  556 473 HOH HOH C . 
Q 5 HOH 57  557 488 HOH HOH C . 
Q 5 HOH 58  558 832 HOH HOH C . 
Q 5 HOH 59  559 708 HOH HOH C . 
Q 5 HOH 60  560 411 HOH HOH C . 
Q 5 HOH 61  561 680 HOH HOH C . 
Q 5 HOH 62  562 455 HOH HOH C . 
Q 5 HOH 63  563 664 HOH HOH C . 
Q 5 HOH 64  564 547 HOH HOH C . 
Q 5 HOH 65  565 93  HOH HOH C . 
Q 5 HOH 66  566 33  HOH HOH C . 
Q 5 HOH 67  567 266 HOH HOH C . 
Q 5 HOH 68  568 52  HOH HOH C . 
Q 5 HOH 69  569 347 HOH HOH C . 
Q 5 HOH 70  570 225 HOH HOH C . 
Q 5 HOH 71  571 199 HOH HOH C . 
Q 5 HOH 72  572 180 HOH HOH C . 
Q 5 HOH 73  573 402 HOH HOH C . 
Q 5 HOH 74  574 400 HOH HOH C . 
Q 5 HOH 75  575 54  HOH HOH C . 
Q 5 HOH 76  576 838 HOH HOH C . 
Q 5 HOH 77  577 117 HOH HOH C . 
Q 5 HOH 78  578 781 HOH HOH C . 
Q 5 HOH 79  579 579 HOH HOH C . 
Q 5 HOH 80  580 667 HOH HOH C . 
Q 5 HOH 81  581 426 HOH HOH C . 
Q 5 HOH 82  582 403 HOH HOH C . 
Q 5 HOH 83  583 617 HOH HOH C . 
Q 5 HOH 84  584 722 HOH HOH C . 
Q 5 HOH 85  585 599 HOH HOH C . 
Q 5 HOH 86  586 821 HOH HOH C . 
Q 5 HOH 87  587 441 HOH HOH C . 
Q 5 HOH 88  588 438 HOH HOH C . 
Q 5 HOH 89  589 355 HOH HOH C . 
Q 5 HOH 90  590 576 HOH HOH C . 
Q 5 HOH 91  591 530 HOH HOH C . 
Q 5 HOH 92  592 693 HOH HOH C . 
Q 5 HOH 93  593 110 HOH HOH C . 
Q 5 HOH 94  594 429 HOH HOH C . 
Q 5 HOH 95  595 390 HOH HOH C . 
Q 5 HOH 96  596 161 HOH HOH C . 
Q 5 HOH 97  597 417 HOH HOH C . 
Q 5 HOH 98  598 734 HOH HOH C . 
Q 5 HOH 99  599 580 HOH HOH C . 
Q 5 HOH 100 600 471 HOH HOH C . 
Q 5 HOH 101 601 567 HOH HOH C . 
Q 5 HOH 102 602 9   HOH HOH C . 
Q 5 HOH 103 603 16  HOH HOH C . 
Q 5 HOH 104 604 662 HOH HOH C . 
Q 5 HOH 105 605 179 HOH HOH C . 
Q 5 HOH 106 606 288 HOH HOH C . 
Q 5 HOH 107 607 810 HOH HOH C . 
Q 5 HOH 108 608 486 HOH HOH C . 
Q 5 HOH 109 609 332 HOH HOH C . 
Q 5 HOH 110 610 702 HOH HOH C . 
Q 5 HOH 111 611 749 HOH HOH C . 
Q 5 HOH 112 612 418 HOH HOH C . 
Q 5 HOH 113 613 196 HOH HOH C . 
Q 5 HOH 114 614 48  HOH HOH C . 
Q 5 HOH 115 615 164 HOH HOH C . 
Q 5 HOH 116 616 147 HOH HOH C . 
Q 5 HOH 117 617 528 HOH HOH C . 
Q 5 HOH 118 618 804 HOH HOH C . 
Q 5 HOH 119 619 759 HOH HOH C . 
Q 5 HOH 120 620 312 HOH HOH C . 
Q 5 HOH 121 621 307 HOH HOH C . 
Q 5 HOH 122 622 435 HOH HOH C . 
Q 5 HOH 123 623 221 HOH HOH C . 
Q 5 HOH 124 624 328 HOH HOH C . 
Q 5 HOH 125 625 238 HOH HOH C . 
Q 5 HOH 126 626 842 HOH HOH C . 
Q 5 HOH 127 627 631 HOH HOH C . 
Q 5 HOH 128 628 314 HOH HOH C . 
Q 5 HOH 129 629 514 HOH HOH C . 
Q 5 HOH 130 630 746 HOH HOH C . 
Q 5 HOH 131 631 733 HOH HOH C . 
Q 5 HOH 132 632 301 HOH HOH C . 
Q 5 HOH 133 633 876 HOH HOH C . 
Q 5 HOH 134 634 878 HOH HOH C . 
Q 5 HOH 135 635 866 HOH HOH C . 
Q 5 HOH 136 636 383 HOH HOH C . 
R 5 HOH 1   601 316 HOH HOH D . 
R 5 HOH 2   602 805 HOH HOH D . 
R 5 HOH 3   603 358 HOH HOH D . 
R 5 HOH 4   604 102 HOH HOH D . 
R 5 HOH 5   605 540 HOH HOH D . 
R 5 HOH 6   606 78  HOH HOH D . 
R 5 HOH 7   607 60  HOH HOH D . 
R 5 HOH 8   608 587 HOH HOH D . 
R 5 HOH 9   609 74  HOH HOH D . 
R 5 HOH 10  610 360 HOH HOH D . 
R 5 HOH 11  611 210 HOH HOH D . 
R 5 HOH 12  612 317 HOH HOH D . 
R 5 HOH 13  613 802 HOH HOH D . 
R 5 HOH 14  614 138 HOH HOH D . 
R 5 HOH 15  615 377 HOH HOH D . 
R 5 HOH 16  616 143 HOH HOH D . 
R 5 HOH 17  617 457 HOH HOH D . 
R 5 HOH 18  618 41  HOH HOH D . 
R 5 HOH 19  619 673 HOH HOH D . 
R 5 HOH 20  620 131 HOH HOH D . 
R 5 HOH 21  621 107 HOH HOH D . 
R 5 HOH 22  622 557 HOH HOH D . 
R 5 HOH 23  623 137 HOH HOH D . 
R 5 HOH 24  624 303 HOH HOH D . 
R 5 HOH 25  625 340 HOH HOH D . 
R 5 HOH 26  626 153 HOH HOH D . 
R 5 HOH 27  627 207 HOH HOH D . 
R 5 HOH 28  628 450 HOH HOH D . 
R 5 HOH 29  629 204 HOH HOH D . 
R 5 HOH 30  630 252 HOH HOH D . 
R 5 HOH 31  631 80  HOH HOH D . 
R 5 HOH 32  632 577 HOH HOH D . 
R 5 HOH 33  633 67  HOH HOH D . 
R 5 HOH 34  634 261 HOH HOH D . 
R 5 HOH 35  635 357 HOH HOH D . 
R 5 HOH 36  636 620 HOH HOH D . 
R 5 HOH 37  637 494 HOH HOH D . 
R 5 HOH 38  638 202 HOH HOH D . 
R 5 HOH 39  639 302 HOH HOH D . 
R 5 HOH 40  640 213 HOH HOH D . 
R 5 HOH 41  641 100 HOH HOH D . 
R 5 HOH 42  642 754 HOH HOH D . 
R 5 HOH 43  643 63  HOH HOH D . 
R 5 HOH 44  644 119 HOH HOH D . 
R 5 HOH 45  645 738 HOH HOH D . 
R 5 HOH 46  646 425 HOH HOH D . 
R 5 HOH 47  647 338 HOH HOH D . 
R 5 HOH 48  648 298 HOH HOH D . 
R 5 HOH 49  649 113 HOH HOH D . 
R 5 HOH 50  650 116 HOH HOH D . 
R 5 HOH 51  651 839 HOH HOH D . 
R 5 HOH 52  652 737 HOH HOH D . 
R 5 HOH 53  653 114 HOH HOH D . 
R 5 HOH 54  654 541 HOH HOH D . 
R 5 HOH 55  655 479 HOH HOH D . 
R 5 HOH 56  656 684 HOH HOH D . 
R 5 HOH 57  657 337 HOH HOH D . 
R 5 HOH 58  658 92  HOH HOH D . 
R 5 HOH 59  659 596 HOH HOH D . 
R 5 HOH 60  660 71  HOH HOH D . 
R 5 HOH 61  661 590 HOH HOH D . 
R 5 HOH 62  662 36  HOH HOH D . 
R 5 HOH 63  663 586 HOH HOH D . 
R 5 HOH 64  664 12  HOH HOH D . 
R 5 HOH 65  665 19  HOH HOH D . 
R 5 HOH 66  666 492 HOH HOH D . 
R 5 HOH 67  667 214 HOH HOH D . 
R 5 HOH 68  668 835 HOH HOH D . 
R 5 HOH 69  669 558 HOH HOH D . 
R 5 HOH 70  670 185 HOH HOH D . 
R 5 HOH 71  671 467 HOH HOH D . 
R 5 HOH 72  672 97  HOH HOH D . 
R 5 HOH 73  673 786 HOH HOH D . 
R 5 HOH 74  674 287 HOH HOH D . 
R 5 HOH 75  675 368 HOH HOH D . 
R 5 HOH 76  676 281 HOH HOH D . 
R 5 HOH 77  677 850 HOH HOH D . 
R 5 HOH 78  678 257 HOH HOH D . 
R 5 HOH 79  679 865 HOH HOH D . 
R 5 HOH 80  680 704 HOH HOH D . 
R 5 HOH 81  681 711 HOH HOH D . 
R 5 HOH 82  682 65  HOH HOH D . 
R 5 HOH 83  683 349 HOH HOH D . 
R 5 HOH 84  684 352 HOH HOH D . 
R 5 HOH 85  685 280 HOH HOH D . 
R 5 HOH 86  686 630 HOH HOH D . 
R 5 HOH 87  687 650 HOH HOH D . 
R 5 HOH 88  688 134 HOH HOH D . 
R 5 HOH 89  689 75  HOH HOH D . 
R 5 HOH 90  690 549 HOH HOH D . 
R 5 HOH 91  691 501 HOH HOH D . 
R 5 HOH 92  692 787 HOH HOH D . 
R 5 HOH 93  693 707 HOH HOH D . 
R 5 HOH 94  694 542 HOH HOH D . 
R 5 HOH 95  695 592 HOH HOH D . 
R 5 HOH 96  696 641 HOH HOH D . 
R 5 HOH 97  697 62  HOH HOH D . 
R 5 HOH 98  698 274 HOH HOH D . 
R 5 HOH 99  699 341 HOH HOH D . 
R 5 HOH 100 700 841 HOH HOH D . 
R 5 HOH 101 701 325 HOH HOH D . 
R 5 HOH 102 702 484 HOH HOH D . 
R 5 HOH 103 703 633 HOH HOH D . 
R 5 HOH 104 704 364 HOH HOH D . 
R 5 HOH 105 705 751 HOH HOH D . 
R 5 HOH 106 706 8   HOH HOH D . 
R 5 HOH 107 707 762 HOH HOH D . 
R 5 HOH 108 708 395 HOH HOH D . 
R 5 HOH 109 709 171 HOH HOH D . 
R 5 HOH 110 710 818 HOH HOH D . 
R 5 HOH 111 711 50  HOH HOH D . 
R 5 HOH 112 712 797 HOH HOH D . 
R 5 HOH 113 713 594 HOH HOH D . 
R 5 HOH 114 714 191 HOH HOH D . 
R 5 HOH 115 715 428 HOH HOH D . 
R 5 HOH 116 716 616 HOH HOH D . 
R 5 HOH 117 717 780 HOH HOH D . 
R 5 HOH 118 718 123 HOH HOH D . 
R 5 HOH 119 719 11  HOH HOH D . 
R 5 HOH 120 720 7   HOH HOH D . 
R 5 HOH 121 721 520 HOH HOH D . 
R 5 HOH 122 722 808 HOH HOH D . 
R 5 HOH 123 723 24  HOH HOH D . 
R 5 HOH 124 724 646 HOH HOH D . 
R 5 HOH 125 725 775 HOH HOH D . 
R 5 HOH 126 726 571 HOH HOH D . 
R 5 HOH 127 727 188 HOH HOH D . 
R 5 HOH 128 728 392 HOH HOH D . 
R 5 HOH 129 729 206 HOH HOH D . 
R 5 HOH 130 730 495 HOH HOH D . 
R 5 HOH 131 731 572 HOH HOH D . 
R 5 HOH 132 732 634 HOH HOH D . 
R 5 HOH 133 733 459 HOH HOH D . 
R 5 HOH 134 734 812 HOH HOH D . 
R 5 HOH 135 735 564 HOH HOH D . 
R 5 HOH 136 736 474 HOH HOH D . 
R 5 HOH 137 737 709 HOH HOH D . 
R 5 HOH 138 738 228 HOH HOH D . 
R 5 HOH 139 739 503 HOH HOH D . 
R 5 HOH 140 740 446 HOH HOH D . 
R 5 HOH 141 741 563 HOH HOH D . 
R 5 HOH 142 742 394 HOH HOH D . 
R 5 HOH 143 743 226 HOH HOH D . 
R 5 HOH 144 744 566 HOH HOH D . 
R 5 HOH 145 745 229 HOH HOH D . 
R 5 HOH 146 746 223 HOH HOH D . 
R 5 HOH 147 747 53  HOH HOH D . 
R 5 HOH 148 748 606 HOH HOH D . 
R 5 HOH 149 749 101 HOH HOH D . 
R 5 HOH 150 750 115 HOH HOH D . 
R 5 HOH 151 751 1   HOH HOH D . 
R 5 HOH 152 752 334 HOH HOH D . 
R 5 HOH 153 753 285 HOH HOH D . 
R 5 HOH 154 754 470 HOH HOH D . 
R 5 HOH 155 755 452 HOH HOH D . 
R 5 HOH 156 756 163 HOH HOH D . 
R 5 HOH 157 757 685 HOH HOH D . 
R 5 HOH 158 758 880 HOH HOH D . 
R 5 HOH 159 759 354 HOH HOH D . 
R 5 HOH 160 760 521 HOH HOH D . 
R 5 HOH 161 761 427 HOH HOH D . 
R 5 HOH 162 762 407 HOH HOH D . 
R 5 HOH 163 763 894 HOH HOH D . 
R 5 HOH 164 764 98  HOH HOH D . 
S 5 HOH 1   601 792 HOH HOH E . 
S 5 HOH 2   602 539 HOH HOH E . 
S 5 HOH 3   603 376 HOH HOH E . 
S 5 HOH 4   604 636 HOH HOH E . 
S 5 HOH 5   605 515 HOH HOH E . 
S 5 HOH 6   606 626 HOH HOH E . 
S 5 HOH 7   607 490 HOH HOH E . 
S 5 HOH 8   608 159 HOH HOH E . 
S 5 HOH 9   609 475 HOH HOH E . 
S 5 HOH 10  610 268 HOH HOH E . 
S 5 HOH 11  611 643 HOH HOH E . 
S 5 HOH 12  612 632 HOH HOH E . 
S 5 HOH 13  613 499 HOH HOH E . 
S 5 HOH 14  614 291 HOH HOH E . 
S 5 HOH 15  615 625 HOH HOH E . 
S 5 HOH 16  616 440 HOH HOH E . 
S 5 HOH 17  617 167 HOH HOH E . 
S 5 HOH 18  618 381 HOH HOH E . 
S 5 HOH 19  619 454 HOH HOH E . 
S 5 HOH 20  620 670 HOH HOH E . 
S 5 HOH 21  621 241 HOH HOH E . 
S 5 HOH 22  622 197 HOH HOH E . 
S 5 HOH 23  623 415 HOH HOH E . 
S 5 HOH 24  624 793 HOH HOH E . 
S 5 HOH 25  625 111 HOH HOH E . 
S 5 HOH 26  626 126 HOH HOH E . 
S 5 HOH 27  627 831 HOH HOH E . 
S 5 HOH 28  628 250 HOH HOH E . 
S 5 HOH 29  629 379 HOH HOH E . 
S 5 HOH 30  630 653 HOH HOH E . 
S 5 HOH 31  631 877 HOH HOH E . 
S 5 HOH 32  632 538 HOH HOH E . 
S 5 HOH 33  633 152 HOH HOH E . 
S 5 HOH 34  634 595 HOH HOH E . 
S 5 HOH 35  635 371 HOH HOH E . 
S 5 HOH 36  636 273 HOH HOH E . 
S 5 HOH 37  637 723 HOH HOH E . 
S 5 HOH 38  638 305 HOH HOH E . 
S 5 HOH 39  639 363 HOH HOH E . 
S 5 HOH 40  640 505 HOH HOH E . 
S 5 HOH 41  641 640 HOH HOH E . 
S 5 HOH 42  642 85  HOH HOH E . 
S 5 HOH 43  643 324 HOH HOH E . 
S 5 HOH 44  644 144 HOH HOH E . 
S 5 HOH 45  645 747 HOH HOH E . 
S 5 HOH 46  646 661 HOH HOH E . 
S 5 HOH 47  647 561 HOH HOH E . 
S 5 HOH 48  648 155 HOH HOH E . 
S 5 HOH 49  649 565 HOH HOH E . 
S 5 HOH 50  650 773 HOH HOH E . 
S 5 HOH 51  651 313 HOH HOH E . 
S 5 HOH 52  652 743 HOH HOH E . 
S 5 HOH 53  653 44  HOH HOH E . 
S 5 HOH 54  654 624 HOH HOH E . 
S 5 HOH 55  655 568 HOH HOH E . 
S 5 HOH 56  656 13  HOH HOH E . 
S 5 HOH 57  657 694 HOH HOH E . 
S 5 HOH 58  658 562 HOH HOH E . 
S 5 HOH 59  659 306 HOH HOH E . 
S 5 HOH 60  660 69  HOH HOH E . 
S 5 HOH 61  661 833 HOH HOH E . 
S 5 HOH 62  662 248 HOH HOH E . 
S 5 HOH 63  663 757 HOH HOH E . 
S 5 HOH 64  664 686 HOH HOH E . 
S 5 HOH 65  665 697 HOH HOH E . 
S 5 HOH 66  666 151 HOH HOH E . 
S 5 HOH 67  667 168 HOH HOH E . 
S 5 HOH 68  668 544 HOH HOH E . 
S 5 HOH 69  669 761 HOH HOH E . 
S 5 HOH 70  670 405 HOH HOH E . 
S 5 HOH 71  671 304 HOH HOH E . 
S 5 HOH 72  672 817 HOH HOH E . 
S 5 HOH 73  673 848 HOH HOH E . 
S 5 HOH 74  674 756 HOH HOH E . 
S 5 HOH 75  675 496 HOH HOH E . 
S 5 HOH 76  676 31  HOH HOH E . 
S 5 HOH 77  677 766 HOH HOH E . 
S 5 HOH 78  678 867 HOH HOH E . 
S 5 HOH 79  679 136 HOH HOH E . 
S 5 HOH 80  680 139 HOH HOH E . 
S 5 HOH 81  681 156 HOH HOH E . 
S 5 HOH 82  682 135 HOH HOH E . 
S 5 HOH 83  683 141 HOH HOH E . 
S 5 HOH 84  684 118 HOH HOH E . 
S 5 HOH 85  685 506 HOH HOH E . 
S 5 HOH 86  686 875 HOH HOH E . 
S 5 HOH 87  687 849 HOH HOH E . 
S 5 HOH 88  688 173 HOH HOH E . 
S 5 HOH 89  689 104 HOH HOH E . 
S 5 HOH 90  690 237 HOH HOH E . 
S 5 HOH 91  691 10  HOH HOH E . 
S 5 HOH 92  692 752 HOH HOH E . 
S 5 HOH 93  693 652 HOH HOH E . 
S 5 HOH 94  694 556 HOH HOH E . 
S 5 HOH 95  695 649 HOH HOH E . 
S 5 HOH 96  696 120 HOH HOH E . 
S 5 HOH 97  697 414 HOH HOH E . 
S 5 HOH 98  698 658 HOH HOH E . 
S 5 HOH 99  699 70  HOH HOH E . 
S 5 HOH 100 700 511 HOH HOH E . 
S 5 HOH 101 701 560 HOH HOH E . 
S 5 HOH 102 702 385 HOH HOH E . 
S 5 HOH 103 703 745 HOH HOH E . 
S 5 HOH 104 704 846 HOH HOH E . 
S 5 HOH 105 705 851 HOH HOH E . 
S 5 HOH 106 706 657 HOH HOH E . 
S 5 HOH 107 707 27  HOH HOH E . 
S 5 HOH 108 708 322 HOH HOH E . 
S 5 HOH 109 709 753 HOH HOH E . 
S 5 HOH 110 710 198 HOH HOH E . 
S 5 HOH 111 711 145 HOH HOH E . 
S 5 HOH 112 712 271 HOH HOH E . 
S 5 HOH 113 713 397 HOH HOH E . 
S 5 HOH 114 714 68  HOH HOH E . 
S 5 HOH 115 715 263 HOH HOH E . 
S 5 HOH 116 716 679 HOH HOH E . 
S 5 HOH 117 717 591 HOH HOH E . 
S 5 HOH 118 718 672 HOH HOH E . 
S 5 HOH 119 719 423 HOH HOH E . 
S 5 HOH 120 720 447 HOH HOH E . 
S 5 HOH 121 721 703 HOH HOH E . 
S 5 HOH 122 722 615 HOH HOH E . 
S 5 HOH 123 723 609 HOH HOH E . 
S 5 HOH 124 724 18  HOH HOH E . 
S 5 HOH 125 725 232 HOH HOH E . 
S 5 HOH 126 726 799 HOH HOH E . 
S 5 HOH 127 727 26  HOH HOH E . 
S 5 HOH 128 728 893 HOH HOH E . 
S 5 HOH 129 729 481 HOH HOH E . 
S 5 HOH 130 730 788 HOH HOH E . 
S 5 HOH 131 731 881 HOH HOH E . 
S 5 HOH 132 732 28  HOH HOH E . 
S 5 HOH 133 733 456 HOH HOH E . 
S 5 HOH 134 734 404 HOH HOH E . 
S 5 HOH 135 735 464 HOH HOH E . 
S 5 HOH 136 736 346 HOH HOH E . 
S 5 HOH 137 737 854 HOH HOH E . 
S 5 HOH 138 738 194 HOH HOH E . 
S 5 HOH 139 739 895 HOH HOH E . 
S 5 HOH 140 740 888 HOH HOH E . 
S 5 HOH 141 741 527 HOH HOH E . 
S 5 HOH 142 742 890 HOH HOH E . 
S 5 HOH 143 743 847 HOH HOH E . 
S 5 HOH 144 744 613 HOH HOH E . 
S 5 HOH 145 745 224 HOH HOH E . 
S 5 HOH 146 746 659 HOH HOH E . 
S 5 HOH 147 747 710 HOH HOH E . 
T 5 HOH 1   601 162 HOH HOH F . 
T 5 HOH 2   602 169 HOH HOH F . 
T 5 HOH 3   603 331 HOH HOH F . 
T 5 HOH 4   604 190 HOH HOH F . 
T 5 HOH 5   605 635 HOH HOH F . 
T 5 HOH 6   606 768 HOH HOH F . 
T 5 HOH 7   607 628 HOH HOH F . 
T 5 HOH 8   608 642 HOH HOH F . 
T 5 HOH 9   609 860 HOH HOH F . 
T 5 HOH 10  610 610 HOH HOH F . 
T 5 HOH 11  611 622 HOH HOH F . 
T 5 HOH 12  612 777 HOH HOH F . 
T 5 HOH 13  613 460 HOH HOH F . 
T 5 HOH 14  614 294 HOH HOH F . 
T 5 HOH 15  615 627 HOH HOH F . 
T 5 HOH 16  616 706 HOH HOH F . 
T 5 HOH 17  617 112 HOH HOH F . 
T 5 HOH 18  618 239 HOH HOH F . 
T 5 HOH 19  619 493 HOH HOH F . 
T 5 HOH 20  620 445 HOH HOH F . 
T 5 HOH 21  621 278 HOH HOH F . 
T 5 HOH 22  622 755 HOH HOH F . 
T 5 HOH 23  623 705 HOH HOH F . 
T 5 HOH 24  624 193 HOH HOH F . 
T 5 HOH 25  625 660 HOH HOH F . 
T 5 HOH 26  626 837 HOH HOH F . 
T 5 HOH 27  627 245 HOH HOH F . 
T 5 HOH 28  628 94  HOH HOH F . 
T 5 HOH 29  629 181 HOH HOH F . 
T 5 HOH 30  630 387 HOH HOH F . 
T 5 HOH 31  631 293 HOH HOH F . 
T 5 HOH 32  632 728 HOH HOH F . 
T 5 HOH 33  633 209 HOH HOH F . 
T 5 HOH 34  634 189 HOH HOH F . 
T 5 HOH 35  635 868 HOH HOH F . 
T 5 HOH 36  636 275 HOH HOH F . 
T 5 HOH 37  637 105 HOH HOH F . 
T 5 HOH 38  638 251 HOH HOH F . 
T 5 HOH 39  639 51  HOH HOH F . 
T 5 HOH 40  640 64  HOH HOH F . 
T 5 HOH 41  641 351 HOH HOH F . 
T 5 HOH 42  642 691 HOH HOH F . 
T 5 HOH 43  643 623 HOH HOH F . 
T 5 HOH 44  644 374 HOH HOH F . 
T 5 HOH 45  645 34  HOH HOH F . 
T 5 HOH 46  646 282 HOH HOH F . 
T 5 HOH 47  647 299 HOH HOH F . 
T 5 HOH 48  648 463 HOH HOH F . 
T 5 HOH 49  649 265 HOH HOH F . 
T 5 HOH 50  650 537 HOH HOH F . 
T 5 HOH 51  651 782 HOH HOH F . 
T 5 HOH 52  652 809 HOH HOH F . 
T 5 HOH 53  653 573 HOH HOH F . 
T 5 HOH 54  654 681 HOH HOH F . 
T 5 HOH 55  655 242 HOH HOH F . 
T 5 HOH 56  656 46  HOH HOH F . 
T 5 HOH 57  657 243 HOH HOH F . 
T 5 HOH 58  658 713 HOH HOH F . 
T 5 HOH 59  659 343 HOH HOH F . 
T 5 HOH 60  660 73  HOH HOH F . 
T 5 HOH 61  661 603 HOH HOH F . 
T 5 HOH 62  662 432 HOH HOH F . 
T 5 HOH 63  663 378 HOH HOH F . 
T 5 HOH 64  664 359 HOH HOH F . 
T 5 HOH 65  665 811 HOH HOH F . 
T 5 HOH 66  666 535 HOH HOH F . 
T 5 HOH 67  667 690 HOH HOH F . 
T 5 HOH 68  668 215 HOH HOH F . 
T 5 HOH 69  669 574 HOH HOH F . 
T 5 HOH 70  670 286 HOH HOH F . 
T 5 HOH 71  671 408 HOH HOH F . 
T 5 HOH 72  672 604 HOH HOH F . 
T 5 HOH 73  673 45  HOH HOH F . 
T 5 HOH 74  674 320 HOH HOH F . 
T 5 HOH 75  675 382 HOH HOH F . 
T 5 HOH 76  676 174 HOH HOH F . 
T 5 HOH 77  677 247 HOH HOH F . 
T 5 HOH 78  678 244 HOH HOH F . 
T 5 HOH 79  679 362 HOH HOH F . 
T 5 HOH 80  680 330 HOH HOH F . 
T 5 HOH 81  681 422 HOH HOH F . 
T 5 HOH 82  682 90  HOH HOH F . 
T 5 HOH 83  683 419 HOH HOH F . 
T 5 HOH 84  684 270 HOH HOH F . 
T 5 HOH 85  685 796 HOH HOH F . 
T 5 HOH 86  686 380 HOH HOH F . 
T 5 HOH 87  687 95  HOH HOH F . 
T 5 HOH 88  688 548 HOH HOH F . 
T 5 HOH 89  689 178 HOH HOH F . 
T 5 HOH 90  690 277 HOH HOH F . 
T 5 HOH 91  691 740 HOH HOH F . 
T 5 HOH 92  692 823 HOH HOH F . 
T 5 HOH 93  693 150 HOH HOH F . 
T 5 HOH 94  694 130 HOH HOH F . 
T 5 HOH 95  695 369 HOH HOH F . 
T 5 HOH 96  696 674 HOH HOH F . 
T 5 HOH 97  697 66  HOH HOH F . 
T 5 HOH 98  698 240 HOH HOH F . 
T 5 HOH 99  699 748 HOH HOH F . 
T 5 HOH 100 700 677 HOH HOH F . 
T 5 HOH 101 701 778 HOH HOH F . 
T 5 HOH 102 702 840 HOH HOH F . 
T 5 HOH 103 703 183 HOH HOH F . 
T 5 HOH 104 704 637 HOH HOH F . 
T 5 HOH 105 705 449 HOH HOH F . 
T 5 HOH 106 706 656 HOH HOH F . 
T 5 HOH 107 707 744 HOH HOH F . 
T 5 HOH 108 708 442 HOH HOH F . 
T 5 HOH 109 709 864 HOH HOH F . 
T 5 HOH 110 710 345 HOH HOH F . 
T 5 HOH 111 711 96  HOH HOH F . 
T 5 HOH 112 712 682 HOH HOH F . 
T 5 HOH 113 713 621 HOH HOH F . 
T 5 HOH 114 714 611 HOH HOH F . 
T 5 HOH 115 715 176 HOH HOH F . 
T 5 HOH 116 716 165 HOH HOH F . 
T 5 HOH 117 717 695 HOH HOH F . 
T 5 HOH 118 718 462 HOH HOH F . 
T 5 HOH 119 719 3   HOH HOH F . 
T 5 HOH 120 720 552 HOH HOH F . 
T 5 HOH 121 721 353 HOH HOH F . 
T 5 HOH 122 722 292 HOH HOH F . 
T 5 HOH 123 723 512 HOH HOH F . 
T 5 HOH 124 724 645 HOH HOH F . 
T 5 HOH 125 725 597 HOH HOH F . 
T 5 HOH 126 726 76  HOH HOH F . 
T 5 HOH 127 727 763 HOH HOH F . 
T 5 HOH 128 728 469 HOH HOH F . 
T 5 HOH 129 729 253 HOH HOH F . 
T 5 HOH 130 730 348 HOH HOH F . 
T 5 HOH 131 731 21  HOH HOH F . 
T 5 HOH 132 732 648 HOH HOH F . 
T 5 HOH 133 733 852 HOH HOH F . 
T 5 HOH 134 734 508 HOH HOH F . 
T 5 HOH 135 735 22  HOH HOH F . 
T 5 HOH 136 736 717 HOH HOH F . 
T 5 HOH 137 737 896 HOH HOH F . 
T 5 HOH 138 738 272 HOH HOH F . 
T 5 HOH 139 739 30  HOH HOH F . 
T 5 HOH 140 740 500 HOH HOH F . 
T 5 HOH 141 741 518 HOH HOH F . 
T 5 HOH 142 742 393 HOH HOH F . 
T 5 HOH 143 743 504 HOH HOH F . 
T 5 HOH 144 744 803 HOH HOH F . 
T 5 HOH 145 745 476 HOH HOH F . 
T 5 HOH 146 746 258 HOH HOH F . 
T 5 HOH 147 747 321 HOH HOH F . 
T 5 HOH 148 748 807 HOH HOH F . 
T 5 HOH 149 749 602 HOH HOH F . 
T 5 HOH 150 750 32  HOH HOH F . 
T 5 HOH 151 751 836 HOH HOH F . 
T 5 HOH 152 752 510 HOH HOH F . 
T 5 HOH 153 753 533 HOH HOH F . 
T 5 HOH 154 754 366 HOH HOH F . 
T 5 HOH 155 755 522 HOH HOH F . 
T 5 HOH 156 756 524 HOH HOH F . 
T 5 HOH 157 757 526 HOH HOH F . 
T 5 HOH 158 758 133 HOH HOH F . 
T 5 HOH 159 759 534 HOH HOH F . 
T 5 HOH 160 760 333 HOH HOH F . 
T 5 HOH 161 761 826 HOH HOH F . 
T 5 HOH 162 762 443 HOH HOH F . 
T 5 HOH 163 763 531 HOH HOH F . 
T 5 HOH 164 764 513 HOH HOH F . 
T 5 HOH 165 765 412 HOH HOH F . 
T 5 HOH 166 766 772 HOH HOH F . 
T 5 HOH 167 767 498 HOH HOH F . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 B LYS 368 ? CG  ? B LYS 368 CG  
2  1 Y 1 B LYS 368 ? CD  ? B LYS 368 CD  
3  1 Y 1 B LYS 368 ? CE  ? B LYS 368 CE  
4  1 Y 1 B LYS 368 ? NZ  ? B LYS 368 NZ  
5  1 Y 1 C LYS 368 ? CG  ? C LYS 368 CG  
6  1 Y 1 C LYS 368 ? CD  ? C LYS 368 CD  
7  1 Y 1 C LYS 368 ? CE  ? C LYS 368 CE  
8  1 Y 1 C LYS 368 ? NZ  ? C LYS 368 NZ  
9  1 Y 1 C ARG 421 ? CG  ? C ARG 421 CG  
10 1 Y 1 C ARG 421 ? CD  ? C ARG 421 CD  
11 1 Y 1 C ARG 421 ? NE  ? C ARG 421 NE  
12 1 Y 1 C ARG 421 ? CZ  ? C ARG 421 CZ  
13 1 Y 1 C ARG 421 ? NH1 ? C ARG 421 NH1 
14 1 Y 1 C ARG 421 ? NH2 ? C ARG 421 NH2 
15 1 Y 1 E LYS 368 ? CG  ? E LYS 368 CG  
16 1 Y 1 E LYS 368 ? CD  ? E LYS 368 CD  
17 1 Y 1 E LYS 368 ? CE  ? E LYS 368 CE  
18 1 Y 1 E LYS 368 ? NZ  ? E LYS 368 NZ  
19 1 Y 1 E ARG 421 ? CG  ? E ARG 421 CG  
20 1 Y 1 E ARG 421 ? CD  ? E ARG 421 CD  
21 1 Y 1 E ARG 421 ? NE  ? E ARG 421 NE  
22 1 Y 1 E ARG 421 ? CZ  ? E ARG 421 CZ  
23 1 Y 1 E ARG 421 ? NH1 ? E ARG 421 NH1 
24 1 Y 1 E ARG 421 ? NH2 ? E ARG 421 NH2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0419 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? xia2   ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XXF 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     108.490 
_cell.length_a_esd                 ? 
_cell.length_b                     131.760 
_cell.length_b_esd                 ? 
_cell.length_c                     207.240 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XXF 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XXF 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.45 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          49.73 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M BIS-TRIS pH 6.5, 2.4 M Ammonium sulfate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            333.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-03-26 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9792 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9792 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8XXF 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.33 
_reflns.d_resolution_low                               30.15 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     127185 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                11.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          5.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.349 
_reflns.pdbx_Rpim_I_all                                0.139 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.983 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.319 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.33 
_reflns_shell.d_res_low                                     2.39 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.9 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             9287 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.449 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  2.213 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.08 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            -0.18 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            0.10 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               38.029 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.954 
_refine.correlation_coeff_Fo_to_Fc_free          0.918 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8XXF 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.33 
_refine.ls_d_res_low                             30.15 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     120779 
_refine.ls_number_reflns_R_free                  6296 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.89 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.18941 
_refine.ls_R_factor_R_free                       0.24500 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.18654 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.373 
_refine.pdbx_overall_ESU_R_Free                  0.250 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             10.427 
_refine.overall_SU_ML                            0.226 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.33 
_refine_hist.d_res_low                        30.15 
_refine_hist.number_atoms_solvent             883 
_refine_hist.number_atoms_total               22318 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        21435 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.007  0.012  22024 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  20642 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.712  1.850  29871 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.565  1.755  47538 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.728  5.000  2643  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 10.434 5.000  174   ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 15.641 10.000 3685  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.078  0.200  3168  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.006  0.020  25919 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  5136  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.284  3.744  10590 ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.287  3.744  10590 ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.992  6.721  13222 ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.993  6.722  13223 ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 4.054  4.158  11434 ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.054  4.159  11435 ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 6.331  7.466  16649 ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 8.619  35.90  25740 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 8.629  35.91  25644 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.330 
_refine_ls_shell.d_res_low                        2.390 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             482 
_refine_ls_shell.number_reflns_R_work             8737 
_refine_ls_shell.percent_reflns_obs               99.73 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.395 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.401 
# 
_struct.entry_id                     8XXF 
_struct.title                        'TtCS, oxaloacetate, acetyl-CoA complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XXF 
_struct_keywords.text            'citrate synthase, citrate cleavage, reversible, high-temperature crystal, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 1 ? 
E N N 1 ? 
F N N 1 ? 
G N N 2 ? 
H N N 3 ? 
I N N 2 ? 
J N N 2 ? 
K N N 4 ? 
L N N 2 ? 
M N N 2 ? 
N N N 3 ? 
O N N 5 ? 
P N N 5 ? 
Q N N 5 ? 
R N N 5 ? 
S N N 5 ? 
T N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CISY_THET7 
_struct_ref.pdbx_db_accession          A0A0S3QTD0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGS
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XXF A 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
2 1 8XXF B 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
3 1 8XXF C 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
4 1 8XXF D 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
5 1 8XXF E 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
6 1 8XXF F 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XXF LYS A 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 1  
1 8XXF LEU A 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 2  
1 8XXF ALA A 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 3  
1 8XXF ALA A 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 4  
1 8XXF ALA A 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 5  
1 8XXF LEU A 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 6  
1 8XXF GLU A 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 7  
2 8XXF LYS B 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 8  
2 8XXF LEU B 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 9  
2 8XXF ALA B 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 10 
2 8XXF ALA B 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 11 
2 8XXF ALA B 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 12 
2 8XXF LEU B 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 13 
2 8XXF GLU B 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 14 
3 8XXF LYS C 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 15 
3 8XXF LEU C 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 16 
3 8XXF ALA C 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 17 
3 8XXF ALA C 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 18 
3 8XXF ALA C 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 19 
3 8XXF LEU C 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 20 
3 8XXF GLU C 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 21 
4 8XXF LYS D 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 22 
4 8XXF LEU D 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 23 
4 8XXF ALA D 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 24 
4 8XXF ALA D 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 25 
4 8XXF ALA D 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 26 
4 8XXF LEU D 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 27 
4 8XXF GLU D 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 28 
5 8XXF LYS E 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 29 
5 8XXF LEU E 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 30 
5 8XXF ALA E 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 31 
5 8XXF ALA E 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 32 
5 8XXF ALA E 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 33 
5 8XXF LEU E 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 34 
5 8XXF GLU E 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 35 
6 8XXF LYS F 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 36 
6 8XXF LEU F 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 37 
6 8XXF ALA F 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 38 
6 8XXF ALA F 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 39 
6 8XXF ALA F 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 40 
6 8XXF LEU F 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 41 
6 8XXF GLU F 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 42 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1   AA1 MET A 1   ? GLY A 26  ? MET A 1   GLY A 26  1 ? 26 
HELX_P HELX_P2   AA2 ILE A 35  ? GLY A 40  ? ILE A 35  GLY A 40  1 ? 6  
HELX_P HELX_P3   AA3 THR A 67  ? GLY A 74  ? THR A 67  GLY A 74  1 ? 8  
HELX_P HELX_P4   AA4 LEU A 88  ? GLY A 99  ? LEU A 88  GLY A 99  1 ? 12 
HELX_P HELX_P5   AA5 THR A 103 ? MET A 118 ? THR A 103 MET A 118 1 ? 16 
HELX_P HELX_P6   AA6 GLN A 119 ? VAL A 121 ? GLN A 119 VAL A 121 5 ? 3  
HELX_P HELX_P7   AA7 PRO A 122 ? MET A 132 ? PRO A 122 MET A 132 1 ? 11 
HELX_P HELX_P8   AA8 HIS A 137 ? MET A 149 ? HIS A 137 MET A 149 1 ? 13 
HELX_P HELX_P9   AA9 GLN A 150 ? GLU A 152 ? GLN A 150 GLU A 152 5 ? 3  
HELX_P HELX_P10  AB1 SER A 153 ? GLY A 162 ? SER A 153 GLY A 162 1 ? 10 
HELX_P HELX_P11  AB2 ARG A 164 ? GLU A 166 ? ARG A 164 GLU A 166 5 ? 3  
HELX_P HELX_P12  AB3 GLU A 167 ? LYS A 196 ? GLU A 167 LYS A 196 1 ? 30 
HELX_P HELX_P13  AB4 ASP A 208 ? GLY A 218 ? ASP A 208 GLY A 218 1 ? 11 
HELX_P HELX_P14  AB5 ASP A 221 ? HIS A 235 ? ASP A 221 HIS A 235 1 ? 15 
HELX_P HELX_P15  AB6 ASN A 242 ? ALA A 254 ? ASN A 242 ALA A 254 1 ? 13 
HELX_P HELX_P16  AB7 ASP A 257 ? ALA A 270 ? ASP A 257 ALA A 270 1 ? 14 
HELX_P HELX_P17  AB8 GLY A 271 ? LEU A 276 ? GLY A 271 LEU A 276 1 ? 6  
HELX_P HELX_P18  AB9 LEU A 276 ? PHE A 292 ? LEU A 276 PHE A 292 1 ? 17 
HELX_P HELX_P19  AC1 THR A 297 ? SER A 311 ? THR A 297 SER A 311 1 ? 15 
HELX_P HELX_P20  AC2 ASP A 327 ? LEU A 341 ? ASP A 327 LEU A 341 1 ? 15 
HELX_P HELX_P21  AC3 ASP A 344 ? HIS A 364 ? ASP A 344 HIS A 364 1 ? 21 
HELX_P HELX_P22  AC4 VAL A 374 ? TYR A 385 ? VAL A 374 TYR A 385 1 ? 12 
HELX_P HELX_P23  AC5 GLU A 389 ? ASP A 391 ? GLU A 389 ASP A 391 5 ? 3  
HELX_P HELX_P24  AC6 PHE A 392 ? MET A 416 ? PHE A 392 MET A 416 1 ? 25 
HELX_P HELX_P25  AC7 THR A 426 ? ALA A 434 ? THR A 426 ALA A 434 1 ? 9  
HELX_P HELX_P26  AC8 GLU A 435 ? LEU A 437 ? GLU A 435 LEU A 437 5 ? 3  
HELX_P HELX_P27  AC9 LYS B 2   ? GLY B 26  ? LYS B 2   GLY B 26  1 ? 25 
HELX_P HELX_P28  AD1 ILE B 35  ? GLY B 40  ? ILE B 35  GLY B 40  1 ? 6  
HELX_P HELX_P29  AD2 THR B 67  ? GLU B 73  ? THR B 67  GLU B 73  1 ? 7  
HELX_P HELX_P30  AD3 LEU B 88  ? GLY B 99  ? LEU B 88  GLY B 99  1 ? 12 
HELX_P HELX_P31  AD4 THR B 103 ? MET B 118 ? THR B 103 MET B 118 1 ? 16 
HELX_P HELX_P32  AD5 PRO B 122 ? MET B 132 ? PRO B 122 MET B 132 1 ? 11 
HELX_P HELX_P33  AD6 HIS B 137 ? MET B 149 ? HIS B 137 MET B 149 1 ? 13 
HELX_P HELX_P34  AD7 GLN B 150 ? GLU B 152 ? GLN B 150 GLU B 152 5 ? 3  
HELX_P HELX_P35  AD8 SER B 153 ? GLY B 162 ? SER B 153 GLY B 162 1 ? 10 
HELX_P HELX_P36  AD9 ARG B 164 ? GLU B 166 ? ARG B 164 GLU B 166 5 ? 3  
HELX_P HELX_P37  AE1 GLU B 167 ? LYS B 196 ? GLU B 167 LYS B 196 1 ? 30 
HELX_P HELX_P38  AE2 ASP B 208 ? GLY B 218 ? ASP B 208 GLY B 218 1 ? 11 
HELX_P HELX_P39  AE3 ASP B 221 ? HIS B 235 ? ASP B 221 HIS B 235 1 ? 15 
HELX_P HELX_P40  AE4 ASN B 242 ? SER B 253 ? ASN B 242 SER B 253 1 ? 12 
HELX_P HELX_P41  AE5 ASP B 257 ? ALA B 270 ? ASP B 257 ALA B 270 1 ? 14 
HELX_P HELX_P42  AE6 LEU B 276 ? PHE B 292 ? LEU B 276 PHE B 292 1 ? 17 
HELX_P HELX_P43  AE7 THR B 297 ? SER B 311 ? THR B 297 SER B 311 1 ? 15 
HELX_P HELX_P44  AE8 ASP B 327 ? LEU B 341 ? ASP B 327 LEU B 341 1 ? 15 
HELX_P HELX_P45  AE9 ASP B 344 ? GLY B 365 ? ASP B 344 GLY B 365 1 ? 22 
HELX_P HELX_P46  AF1 VAL B 374 ? TYR B 385 ? VAL B 374 TYR B 385 1 ? 12 
HELX_P HELX_P47  AF2 GLU B 389 ? ASP B 391 ? GLU B 389 ASP B 391 5 ? 3  
HELX_P HELX_P48  AF3 PHE B 392 ? MET B 416 ? PHE B 392 MET B 416 1 ? 25 
HELX_P HELX_P49  AF4 THR B 426 ? ALA B 434 ? THR B 426 ALA B 434 1 ? 9  
HELX_P HELX_P50  AF5 GLU B 435 ? LEU B 437 ? GLU B 435 LEU B 437 5 ? 3  
HELX_P HELX_P51  AF6 SER B 442 ? LEU B 448 ? SER B 442 LEU B 448 1 ? 7  
HELX_P HELX_P52  AF7 LYS C 2   ? GLY C 26  ? LYS C 2   GLY C 26  1 ? 25 
HELX_P HELX_P53  AF8 ILE C 35  ? GLY C 40  ? ILE C 35  GLY C 40  1 ? 6  
HELX_P HELX_P54  AF9 THR C 67  ? GLU C 73  ? THR C 67  GLU C 73  1 ? 7  
HELX_P HELX_P55  AG1 LEU C 88  ? GLY C 99  ? LEU C 88  GLY C 99  1 ? 12 
HELX_P HELX_P56  AG2 THR C 103 ? MET C 118 ? THR C 103 MET C 118 1 ? 16 
HELX_P HELX_P57  AG3 PRO C 122 ? MET C 132 ? PRO C 122 MET C 132 1 ? 11 
HELX_P HELX_P58  AG4 HIS C 137 ? MET C 149 ? HIS C 137 MET C 149 1 ? 13 
HELX_P HELX_P59  AG5 GLN C 150 ? GLU C 152 ? GLN C 150 GLU C 152 5 ? 3  
HELX_P HELX_P60  AG6 SER C 153 ? GLY C 162 ? SER C 153 GLY C 162 1 ? 10 
HELX_P HELX_P61  AG7 ARG C 164 ? GLU C 166 ? ARG C 164 GLU C 166 5 ? 3  
HELX_P HELX_P62  AG8 GLU C 167 ? LYS C 196 ? GLU C 167 LYS C 196 1 ? 30 
HELX_P HELX_P63  AG9 ASP C 208 ? GLY C 218 ? ASP C 208 GLY C 218 1 ? 11 
HELX_P HELX_P64  AH1 ASP C 221 ? HIS C 235 ? ASP C 221 HIS C 235 1 ? 15 
HELX_P HELX_P65  AH2 ASN C 242 ? ALA C 254 ? ASN C 242 ALA C 254 1 ? 13 
HELX_P HELX_P66  AH3 ASP C 257 ? ALA C 270 ? ASP C 257 ALA C 270 1 ? 14 
HELX_P HELX_P67  AH4 LEU C 276 ? PHE C 292 ? LEU C 276 PHE C 292 1 ? 17 
HELX_P HELX_P68  AH5 THR C 297 ? SER C 311 ? THR C 297 SER C 311 1 ? 15 
HELX_P HELX_P69  AH6 ASP C 327 ? LEU C 341 ? ASP C 327 LEU C 341 1 ? 15 
HELX_P HELX_P70  AH7 ASP C 344 ? GLY C 365 ? ASP C 344 GLY C 365 1 ? 22 
HELX_P HELX_P71  AH8 ASN C 373 ? ALA C 376 ? ASN C 373 ALA C 376 5 ? 4  
HELX_P HELX_P72  AH9 HIS C 377 ? TYR C 385 ? HIS C 377 TYR C 385 1 ? 9  
HELX_P HELX_P73  AI1 GLU C 389 ? MET C 416 ? GLU C 389 MET C 416 1 ? 28 
HELX_P HELX_P74  AI2 THR C 426 ? ALA C 434 ? THR C 426 ALA C 434 1 ? 9  
HELX_P HELX_P75  AI3 LYS D 2   ? GLY D 26  ? LYS D 2   GLY D 26  1 ? 25 
HELX_P HELX_P76  AI4 ILE D 35  ? GLY D 40  ? ILE D 35  GLY D 40  1 ? 6  
HELX_P HELX_P77  AI5 THR D 67  ? GLU D 73  ? THR D 67  GLU D 73  1 ? 7  
HELX_P HELX_P78  AI6 LEU D 88  ? GLY D 99  ? LEU D 88  GLY D 99  1 ? 12 
HELX_P HELX_P79  AI7 THR D 103 ? MET D 118 ? THR D 103 MET D 118 1 ? 16 
HELX_P HELX_P80  AI8 GLN D 119 ? VAL D 121 ? GLN D 119 VAL D 121 5 ? 3  
HELX_P HELX_P81  AI9 PRO D 122 ? MET D 132 ? PRO D 122 MET D 132 1 ? 11 
HELX_P HELX_P82  AJ1 HIS D 137 ? MET D 149 ? HIS D 137 MET D 149 1 ? 13 
HELX_P HELX_P83  AJ2 GLN D 150 ? GLU D 152 ? GLN D 150 GLU D 152 5 ? 3  
HELX_P HELX_P84  AJ3 SER D 153 ? GLY D 162 ? SER D 153 GLY D 162 1 ? 10 
HELX_P HELX_P85  AJ4 ARG D 164 ? GLU D 166 ? ARG D 164 GLU D 166 5 ? 3  
HELX_P HELX_P86  AJ5 GLU D 167 ? LYS D 196 ? GLU D 167 LYS D 196 1 ? 30 
HELX_P HELX_P87  AJ6 ASP D 208 ? GLY D 218 ? ASP D 208 GLY D 218 1 ? 11 
HELX_P HELX_P88  AJ7 ASP D 221 ? SER D 236 ? ASP D 221 SER D 236 1 ? 16 
HELX_P HELX_P89  AJ8 ASN D 242 ? SER D 253 ? ASN D 242 SER D 253 1 ? 12 
HELX_P HELX_P90  AJ9 ASP D 257 ? ALA D 270 ? ASP D 257 ALA D 270 1 ? 14 
HELX_P HELX_P91  AK1 LEU D 276 ? PHE D 292 ? LEU D 276 PHE D 292 1 ? 17 
HELX_P HELX_P92  AK2 THR D 297 ? SER D 311 ? THR D 297 SER D 311 1 ? 15 
HELX_P HELX_P93  AK3 ASP D 327 ? LEU D 341 ? ASP D 327 LEU D 341 1 ? 15 
HELX_P HELX_P94  AK4 ASP D 344 ? GLY D 365 ? ASP D 344 GLY D 365 1 ? 22 
HELX_P HELX_P95  AK5 VAL D 374 ? GLY D 386 ? VAL D 374 GLY D 386 1 ? 13 
HELX_P HELX_P96  AK6 GLU D 389 ? ASP D 391 ? GLU D 389 ASP D 391 5 ? 3  
HELX_P HELX_P97  AK7 PHE D 392 ? MET D 416 ? PHE D 392 MET D 416 1 ? 25 
HELX_P HELX_P98  AK8 THR D 426 ? ALA D 434 ? THR D 426 ALA D 434 1 ? 9  
HELX_P HELX_P99  AK9 GLU D 435 ? LEU D 437 ? GLU D 435 LEU D 437 5 ? 3  
HELX_P HELX_P100 AL1 LYS E 2   ? GLY E 26  ? LYS E 2   GLY E 26  1 ? 25 
HELX_P HELX_P101 AL2 ILE E 35  ? TYR E 39  ? ILE E 35  TYR E 39  1 ? 5  
HELX_P HELX_P102 AL3 THR E 67  ? GLU E 73  ? THR E 67  GLU E 73  1 ? 7  
HELX_P HELX_P103 AL4 LEU E 88  ? GLY E 99  ? LEU E 88  GLY E 99  1 ? 12 
HELX_P HELX_P104 AL5 THR E 103 ? MET E 118 ? THR E 103 MET E 118 1 ? 16 
HELX_P HELX_P105 AL6 PRO E 122 ? MET E 132 ? PRO E 122 MET E 132 1 ? 11 
HELX_P HELX_P106 AL7 HIS E 137 ? MET E 149 ? HIS E 137 MET E 149 1 ? 13 
HELX_P HELX_P107 AL8 GLN E 150 ? GLU E 152 ? GLN E 150 GLU E 152 5 ? 3  
HELX_P HELX_P108 AL9 SER E 153 ? GLY E 162 ? SER E 153 GLY E 162 1 ? 10 
HELX_P HELX_P109 AM1 ARG E 164 ? GLU E 166 ? ARG E 164 GLU E 166 5 ? 3  
HELX_P HELX_P110 AM2 GLU E 167 ? LYS E 196 ? GLU E 167 LYS E 196 1 ? 30 
HELX_P HELX_P111 AM3 ASP E 208 ? GLY E 218 ? ASP E 208 GLY E 218 1 ? 11 
HELX_P HELX_P112 AM4 ASP E 221 ? HIS E 235 ? ASP E 221 HIS E 235 1 ? 15 
HELX_P HELX_P113 AM5 ASN E 242 ? SER E 253 ? ASN E 242 SER E 253 1 ? 12 
HELX_P HELX_P114 AM6 ASP E 257 ? ALA E 270 ? ASP E 257 ALA E 270 1 ? 14 
HELX_P HELX_P115 AM7 LEU E 276 ? PHE E 292 ? LEU E 276 PHE E 292 1 ? 17 
HELX_P HELX_P116 AM8 THR E 297 ? ASN E 310 ? THR E 297 ASN E 310 1 ? 14 
HELX_P HELX_P117 AM9 ASP E 327 ? LEU E 341 ? ASP E 327 LEU E 341 1 ? 15 
HELX_P HELX_P118 AN1 ASP E 344 ? GLY E 365 ? ASP E 344 GLY E 365 1 ? 22 
HELX_P HELX_P119 AN2 ASN E 373 ? ALA E 376 ? ASN E 373 ALA E 376 5 ? 4  
HELX_P HELX_P120 AN3 HIS E 377 ? TYR E 385 ? HIS E 377 TYR E 385 1 ? 9  
HELX_P HELX_P121 AN4 GLU E 389 ? ASP E 391 ? GLU E 389 ASP E 391 5 ? 3  
HELX_P HELX_P122 AN5 PHE E 392 ? MET E 416 ? PHE E 392 MET E 416 1 ? 25 
HELX_P HELX_P123 AN6 THR E 426 ? ALA E 434 ? THR E 426 ALA E 434 1 ? 9  
HELX_P HELX_P124 AN7 GLU E 435 ? LEU E 437 ? GLU E 435 LEU E 437 5 ? 3  
HELX_P HELX_P125 AN8 LYS F 2   ? GLY F 26  ? LYS F 2   GLY F 26  1 ? 25 
HELX_P HELX_P126 AN9 ILE F 35  ? GLY F 40  ? ILE F 35  GLY F 40  1 ? 6  
HELX_P HELX_P127 AO1 THR F 67  ? GLU F 73  ? THR F 67  GLU F 73  1 ? 7  
HELX_P HELX_P128 AO2 LEU F 88  ? GLY F 99  ? LEU F 88  GLY F 99  1 ? 12 
HELX_P HELX_P129 AO3 THR F 103 ? MET F 118 ? THR F 103 MET F 118 1 ? 16 
HELX_P HELX_P130 AO4 GLN F 119 ? VAL F 121 ? GLN F 119 VAL F 121 5 ? 3  
HELX_P HELX_P131 AO5 PRO F 122 ? MET F 132 ? PRO F 122 MET F 132 1 ? 11 
HELX_P HELX_P132 AO6 HIS F 137 ? MET F 149 ? HIS F 137 MET F 149 1 ? 13 
HELX_P HELX_P133 AO7 GLN F 150 ? GLU F 152 ? GLN F 150 GLU F 152 5 ? 3  
HELX_P HELX_P134 AO8 SER F 153 ? GLY F 162 ? SER F 153 GLY F 162 1 ? 10 
HELX_P HELX_P135 AO9 ARG F 164 ? GLU F 166 ? ARG F 164 GLU F 166 5 ? 3  
HELX_P HELX_P136 AP1 GLU F 167 ? LYS F 196 ? GLU F 167 LYS F 196 1 ? 30 
HELX_P HELX_P137 AP2 ASP F 208 ? GLY F 218 ? ASP F 208 GLY F 218 1 ? 11 
HELX_P HELX_P138 AP3 ASP F 221 ? HIS F 235 ? ASP F 221 HIS F 235 1 ? 15 
HELX_P HELX_P139 AP4 ASN F 242 ? ALA F 254 ? ASN F 242 ALA F 254 1 ? 13 
HELX_P HELX_P140 AP5 ASP F 257 ? ALA F 270 ? ASP F 257 ALA F 270 1 ? 14 
HELX_P HELX_P141 AP6 LEU F 276 ? PHE F 292 ? LEU F 276 PHE F 292 1 ? 17 
HELX_P HELX_P142 AP7 THR F 297 ? SER F 311 ? THR F 297 SER F 311 1 ? 15 
HELX_P HELX_P143 AP8 ASP F 327 ? LEU F 341 ? ASP F 327 LEU F 341 1 ? 15 
HELX_P HELX_P144 AP9 ASP F 344 ? GLY F 365 ? ASP F 344 GLY F 365 1 ? 22 
HELX_P HELX_P145 AQ1 VAL F 374 ? TYR F 385 ? VAL F 374 TYR F 385 1 ? 12 
HELX_P HELX_P146 AQ2 GLU F 389 ? ASP F 391 ? GLU F 389 ASP F 391 5 ? 3  
HELX_P HELX_P147 AQ3 PHE F 392 ? MET F 416 ? PHE F 392 MET F 416 1 ? 25 
HELX_P HELX_P148 AQ4 THR F 426 ? ALA F 434 ? THR F 426 ALA F 434 1 ? 9  
HELX_P HELX_P149 AQ5 GLU F 435 ? LEU F 437 ? GLU F 435 LEU F 437 5 ? 3  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLY 74 A . ? GLY 74 A PRO 75 A ? PRO 75 A 1 9.29 
2 GLY 74 B . ? GLY 74 B PRO 75 B ? PRO 75 B 1 0.54 
3 GLY 74 D . ? GLY 74 D PRO 75 D ? PRO 75 D 1 3.81 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 2 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? parallel      
AA8 1 2 ? anti-parallel 
AA9 1 2 ? parallel      
AB1 1 2 ? anti-parallel 
AB2 1 2 ? parallel      
AB3 1 2 ? anti-parallel 
AB4 1 2 ? parallel      
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 29  ? THR A 34  ? LYS A 29  THR A 34  
AA1 2 LYS B 29  ? THR B 34  ? LYS B 29  THR B 34  
AA2 1 LYS A 46  ? VAL A 49  ? LYS A 46  VAL A 49  
AA2 2 LYS B 423 ? ILE B 425 ? LYS B 423 ILE B 425 
AA3 1 SER A 53  ? PHE A 56  ? SER A 53  PHE A 56  
AA3 2 GLY A 60  ? PHE A 63  ? GLY A 60  PHE A 63  
AA4 1 LYS A 423 ? ILE A 425 ? LYS A 423 ILE A 425 
AA4 2 LYS B 46  ? VAL B 49  ? LYS B 46  VAL B 49  
AA5 1 SER B 53  ? PHE B 56  ? SER B 53  PHE B 56  
AA5 2 GLY B 60  ? PHE B 63  ? GLY B 60  PHE B 63  
AA6 1 LYS C 29  ? THR C 34  ? LYS C 29  THR C 34  
AA6 2 LYS E 29  ? THR E 34  ? LYS E 29  THR E 34  
AA7 1 LYS C 46  ? VAL C 49  ? LYS C 46  VAL C 49  
AA7 2 LYS E 423 ? ILE E 425 ? LYS E 423 ILE E 425 
AA8 1 SER C 53  ? PHE C 56  ? SER C 53  PHE C 56  
AA8 2 GLY C 60  ? PHE C 63  ? GLY C 60  PHE C 63  
AA9 1 LYS C 423 ? ILE C 425 ? LYS C 423 ILE C 425 
AA9 2 LYS E 46  ? VAL E 49  ? LYS E 46  VAL E 49  
AB1 1 LYS D 29  ? THR D 34  ? LYS D 29  THR D 34  
AB1 2 LYS F 29  ? THR F 34  ? LYS F 29  THR F 34  
AB2 1 LYS D 46  ? VAL D 49  ? LYS D 46  VAL D 49  
AB2 2 LYS F 423 ? ILE F 425 ? LYS F 423 ILE F 425 
AB3 1 SER D 53  ? PHE D 56  ? SER D 53  PHE D 56  
AB3 2 GLY D 60  ? PHE D 63  ? GLY D 60  PHE D 63  
AB4 1 LYS D 423 ? ILE D 425 ? LYS D 423 ILE D 425 
AB4 2 LYS F 46  ? VAL F 49  ? LYS F 46  VAL F 49  
AB5 1 SER E 53  ? PHE E 56  ? SER E 53  PHE E 56  
AB5 2 GLY E 60  ? PHE E 63  ? GLY E 60  PHE E 63  
AB6 1 SER F 53  ? PHE F 56  ? SER F 53  PHE F 56  
AB6 2 GLY F 60  ? PHE F 63  ? GLY F 60  PHE F 63  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 30  ? N THR A 30  O CYS B 33  ? O CYS B 33  
AA2 1 2 N LEU A 48  ? N LEU A 48  O ILE B 425 ? O ILE B 425 
AA3 1 2 N PHE A 56  ? N PHE A 56  O GLY A 60  ? O GLY A 60  
AA4 1 2 N ILE A 425 ? N ILE A 425 O LEU B 48  ? O LEU B 48  
AA5 1 2 N PHE B 56  ? N PHE B 56  O GLY B 60  ? O GLY B 60  
AA6 1 2 N CYS C 33  ? N CYS C 33  O THR E 30  ? O THR E 30  
AA7 1 2 N LEU C 48  ? N LEU C 48  O ILE E 425 ? O ILE E 425 
AA8 1 2 N GLU C 54  ? N GLU C 54  O LYS C 62  ? O LYS C 62  
AA9 1 2 N ILE C 425 ? N ILE C 425 O LEU E 48  ? O LEU E 48  
AB1 1 2 N THR D 30  ? N THR D 30  O CYS F 33  ? O CYS F 33  
AB2 1 2 N LEU D 48  ? N LEU D 48  O ILE F 425 ? O ILE F 425 
AB3 1 2 N PHE D 56  ? N PHE D 56  O GLY D 60  ? O GLY D 60  
AB4 1 2 N ILE D 425 ? N ILE D 425 O LEU F 48  ? O LEU F 48  
AB5 1 2 N PHE E 56  ? N PHE E 56  O GLY E 60  ? O GLY E 60  
AB6 1 2 N PHE F 56  ? N PHE F 56  O GLY F 60  ? O GLY F 60  
# 
_pdbx_entry_details.entry_id                   8XXF 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O F HOH 740 ? ? O F HOH 749 ? ? 1.78 
2 1 O E HOH 713 ? ? O E HOH 724 ? ? 2.04 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CG A MET 232 ? ? SD A MET 232 ? ? CE  A MET 232 ? ? 110.06 100.20 9.86   1.60 N 
2  1 CG A MET 287 ? ? SD A MET 287 ? ? CE  A MET 287 ? ? 112.82 100.20 12.62  1.60 N 
3  1 NE B ARG 151 ? ? CZ B ARG 151 ? ? NH2 B ARG 151 ? ? 116.32 120.30 -3.98  0.50 N 
4  1 NE C ARG 64  ? ? CZ C ARG 64  ? ? NH1 C ARG 64  ? ? 117.07 120.30 -3.23  0.50 N 
5  1 CB C GLU 70  ? ? CA C GLU 70  ? ? C   C GLU 70  ? ? 97.98  110.40 -12.42 2.00 N 
6  1 CG C MET 287 ? ? SD C MET 287 ? ? CE  C MET 287 ? ? 110.42 100.20 10.22  1.60 N 
7  1 CG D ARG 6   ? ? CD D ARG 6   ? ? NE  D ARG 6   ? ? 96.94  111.80 -14.86 2.10 N 
8  1 NE D ARG 64  ? ? CZ D ARG 64  ? ? NH2 D ARG 64  ? ? 123.30 120.30 3.00   0.50 N 
9  1 NE E ARG 413 ? ? CZ E ARG 413 ? ? NH2 E ARG 413 ? ? 116.96 120.30 -3.34  0.50 N 
10 1 CD F ARG 260 ? ? NE F ARG 260 ? ? CZ  F ARG 260 ? ? 132.25 123.60 8.65   1.40 N 
11 1 NE F ARG 260 ? ? CZ F ARG 260 ? ? NH1 F ARG 260 ? ? 126.02 120.30 5.72   0.50 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS A 238 ? ? -150.26 66.35   
2  1 GLU A 239 ? ? 71.10   -177.36 
3  1 VAL A 322 ? ? -144.83 -33.51  
4  1 ARG A 324 ? ? -149.99 -13.69  
5  1 LEU A 341 ? ? -150.65 62.10   
6  1 MET B 42  ? ? 59.28   17.59   
7  1 GLU B 59  ? ? -136.14 -32.03  
8  1 HIS B 238 ? ? -165.86 71.78   
9  1 GLU B 239 ? ? 64.82   -171.86 
10 1 TYR B 255 ? ? 81.82   21.31   
11 1 LEU B 341 ? ? -145.02 47.59   
12 1 LEU B 448 ? ? -100.13 43.71   
13 1 HIS C 238 ? ? -165.36 67.06   
14 1 GLU C 239 ? ? 65.97   -172.20 
15 1 LEU C 341 ? ? -154.26 57.69   
16 1 MET C 416 ? ? 74.45   36.62   
17 1 ARG D 43  ? ? -38.96  113.38  
18 1 GLU D 59  ? ? -135.95 -35.93  
19 1 HIS D 238 ? ? -165.26 64.33   
20 1 GLU D 239 ? ? 71.91   -176.67 
21 1 LEU D 341 ? ? -153.58 56.61   
22 1 MET D 416 ? ? 70.21   46.20   
23 1 ARG D 421 ? ? -154.90 82.34   
24 1 GLU E 59  ? ? -131.71 -48.91  
25 1 HIS E 238 ? ? -157.14 67.04   
26 1 GLU E 239 ? ? 68.11   -175.47 
27 1 LEU E 341 ? ? -153.46 49.64   
28 1 MET E 416 ? ? 70.04   41.25   
29 1 MET F 31  ? ? 179.03  169.67  
30 1 HIS F 238 ? ? -162.12 68.95   
31 1 GLU F 239 ? ? 68.03   -173.85 
32 1 HIS F 274 ? ? -105.36 -126.07 
33 1 LEU F 341 ? ? -149.70 52.55   
34 1 ARG F 421 ? ? -159.95 81.62   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   GLU 
_pdbx_validate_peptide_omega.auth_asym_id_1   E 
_pdbx_validate_peptide_omega.auth_seq_id_1    73 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   GLY 
_pdbx_validate_peptide_omega.auth_asym_id_2   E 
_pdbx_validate_peptide_omega.auth_seq_id_2    74 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -147.93 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 6   ? ? 0.110 'SIDE CHAIN' 
2  1 ARG A 72  ? ? 0.074 'SIDE CHAIN' 
3  1 ARG A 334 ? ? 0.100 'SIDE CHAIN' 
4  1 ARG A 388 ? ? 0.096 'SIDE CHAIN' 
5  1 ARG A 421 ? ? 0.089 'SIDE CHAIN' 
6  1 ARG D 6   ? ? 0.110 'SIDE CHAIN' 
7  1 ARG D 43  ? ? 0.168 'SIDE CHAIN' 
8  1 ARG D 324 ? ? 0.078 'SIDE CHAIN' 
9  1 ARG D 421 ? ? 0.109 'SIDE CHAIN' 
10 1 ARG E 151 ? ? 0.079 'SIDE CHAIN' 
11 1 ARG E 303 ? ? 0.097 'SIDE CHAIN' 
12 1 ARG E 388 ? ? 0.075 'SIDE CHAIN' 
13 1 ARG E 413 ? ? 0.078 'SIDE CHAIN' 
14 1 ARG F 6   ? ? 0.081 'SIDE CHAIN' 
15 1 ARG F 117 ? ? 0.078 'SIDE CHAIN' 
16 1 ARG F 413 ? ? 0.076 'SIDE CHAIN' 
# 
_pdbx_distant_solvent_atoms.id                                1 
_pdbx_distant_solvent_atoms.PDB_model_num                     1 
_pdbx_distant_solvent_atoms.auth_atom_id                      O 
_pdbx_distant_solvent_atoms.label_alt_id                      ? 
_pdbx_distant_solvent_atoms.auth_asym_id                      B 
_pdbx_distant_solvent_atoms.auth_comp_id                      HOH 
_pdbx_distant_solvent_atoms.auth_seq_id                       752 
_pdbx_distant_solvent_atoms.PDB_ins_code                      ? 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance   5.99 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance          . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 365 ? A GLY 365 
2  1 Y 1 A LYS 366 ? A LYS 366 
3  1 Y 1 A ALA 367 ? A ALA 367 
4  1 Y 1 A LYS 368 ? A LYS 368 
5  1 Y 1 A ASN 369 ? A ASN 369 
6  1 Y 1 A GLY 441 ? A GLY 441 
7  1 Y 1 A SER 442 ? A SER 442 
8  1 Y 1 A LYS 443 ? A LYS 443 
9  1 Y 1 A LEU 444 ? A LEU 444 
10 1 Y 1 A ALA 445 ? A ALA 445 
11 1 Y 1 A ALA 446 ? A ALA 446 
12 1 Y 1 A ALA 447 ? A ALA 447 
13 1 Y 1 A LEU 448 ? A LEU 448 
14 1 Y 1 A GLU 449 ? A GLU 449 
15 1 Y 1 C LYS 443 ? C LYS 443 
16 1 Y 1 C LEU 444 ? C LEU 444 
17 1 Y 1 C ALA 445 ? C ALA 445 
18 1 Y 1 C ALA 446 ? C ALA 446 
19 1 Y 1 C ALA 447 ? C ALA 447 
20 1 Y 1 C LEU 448 ? C LEU 448 
21 1 Y 1 C GLU 449 ? C GLU 449 
22 1 Y 1 D GLY 441 ? D GLY 441 
23 1 Y 1 D SER 442 ? D SER 442 
24 1 Y 1 D LYS 443 ? D LYS 443 
25 1 Y 1 D LEU 444 ? D LEU 444 
26 1 Y 1 D ALA 445 ? D ALA 445 
27 1 Y 1 D ALA 446 ? D ALA 446 
28 1 Y 1 D ALA 447 ? D ALA 447 
29 1 Y 1 D LEU 448 ? D LEU 448 
30 1 Y 1 D GLU 449 ? D GLU 449 
31 1 Y 1 E SER 442 ? E SER 442 
32 1 Y 1 E LYS 443 ? E LYS 443 
33 1 Y 1 E LEU 444 ? E LEU 444 
34 1 Y 1 E ALA 445 ? E ALA 445 
35 1 Y 1 E ALA 446 ? E ALA 446 
36 1 Y 1 E ALA 447 ? E ALA 447 
37 1 Y 1 E LEU 448 ? E LEU 448 
38 1 Y 1 E GLU 449 ? E GLU 449 
39 1 Y 1 F SER 442 ? F SER 442 
40 1 Y 1 F LYS 443 ? F LYS 443 
41 1 Y 1 F LEU 444 ? F LEU 444 
42 1 Y 1 F ALA 445 ? F ALA 445 
43 1 Y 1 F ALA 446 ? F ALA 446 
44 1 Y 1 F ALA 447 ? F ALA 447 
45 1 Y 1 F LEU 448 ? F LEU 448 
46 1 Y 1 F GLU 449 ? F GLU 449 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ACO N1A  N Y N 1   
ACO C2A  C Y N 2   
ACO N3A  N Y N 3   
ACO C4A  C Y N 4   
ACO C5A  C Y N 5   
ACO C6A  C Y N 6   
ACO N6A  N N N 7   
ACO N7A  N Y N 8   
ACO C8A  C Y N 9   
ACO N9A  N Y N 10  
ACO C1B  C N R 11  
ACO C2B  C N R 12  
ACO O2B  O N N 13  
ACO C3B  C N S 14  
ACO O3B  O N N 15  
ACO P3B  P N N 16  
ACO O7A  O N N 17  
ACO O8A  O N N 18  
ACO O9A  O N N 19  
ACO C4B  C N R 20  
ACO O4B  O N N 21  
ACO C5B  C N N 22  
ACO O5B  O N N 23  
ACO P1A  P N S 24  
ACO O1A  O N N 25  
ACO O2A  O N N 26  
ACO O3A  O N N 27  
ACO P2A  P N S 28  
ACO O4A  O N N 29  
ACO O5A  O N N 30  
ACO O6A  O N N 31  
ACO CBP  C N N 32  
ACO CCP  C N N 33  
ACO CDP  C N N 34  
ACO CEP  C N N 35  
ACO CAP  C N R 36  
ACO OAP  O N N 37  
ACO C9P  C N N 38  
ACO O9P  O N N 39  
ACO N8P  N N N 40  
ACO C7P  C N N 41  
ACO C6P  C N N 42  
ACO C5P  C N N 43  
ACO O5P  O N N 44  
ACO N4P  N N N 45  
ACO C3P  C N N 46  
ACO C2P  C N N 47  
ACO S1P  S N N 48  
ACO C    C N N 49  
ACO O    O N N 50  
ACO CH3  C N N 51  
ACO H2A  H N N 52  
ACO H61A H N N 53  
ACO H62A H N N 54  
ACO H8A  H N N 55  
ACO H1B  H N N 56  
ACO H2B  H N N 57  
ACO HO2A H N N 58  
ACO H3B  H N N 59  
ACO HOA8 H N N 60  
ACO HOA9 H N N 61  
ACO H4B  H N N 62  
ACO H51A H N N 63  
ACO H52A H N N 64  
ACO HOA2 H N N 65  
ACO HOA5 H N N 66  
ACO H121 H N N 67  
ACO H122 H N N 68  
ACO H131 H N N 69  
ACO H132 H N N 70  
ACO H133 H N N 71  
ACO H141 H N N 72  
ACO H142 H N N 73  
ACO H143 H N N 74  
ACO H10  H N N 75  
ACO HO1  H N N 76  
ACO HN8  H N N 77  
ACO H71  H N N 78  
ACO H72  H N N 79  
ACO H61  H N N 80  
ACO H62  H N N 81  
ACO HN4  H N N 82  
ACO H31  H N N 83  
ACO H32  H N N 84  
ACO H21  H N N 85  
ACO H22  H N N 86  
ACO HH31 H N N 87  
ACO HH32 H N N 88  
ACO HH33 H N N 89  
ALA N    N N N 90  
ALA CA   C N S 91  
ALA C    C N N 92  
ALA O    O N N 93  
ALA CB   C N N 94  
ALA OXT  O N N 95  
ALA H    H N N 96  
ALA H2   H N N 97  
ALA HA   H N N 98  
ALA HB1  H N N 99  
ALA HB2  H N N 100 
ALA HB3  H N N 101 
ALA HXT  H N N 102 
ARG N    N N N 103 
ARG CA   C N S 104 
ARG C    C N N 105 
ARG O    O N N 106 
ARG CB   C N N 107 
ARG CG   C N N 108 
ARG CD   C N N 109 
ARG NE   N N N 110 
ARG CZ   C N N 111 
ARG NH1  N N N 112 
ARG NH2  N N N 113 
ARG OXT  O N N 114 
ARG H    H N N 115 
ARG H2   H N N 116 
ARG HA   H N N 117 
ARG HB2  H N N 118 
ARG HB3  H N N 119 
ARG HG2  H N N 120 
ARG HG3  H N N 121 
ARG HD2  H N N 122 
ARG HD3  H N N 123 
ARG HE   H N N 124 
ARG HH11 H N N 125 
ARG HH12 H N N 126 
ARG HH21 H N N 127 
ARG HH22 H N N 128 
ARG HXT  H N N 129 
ASN N    N N N 130 
ASN CA   C N S 131 
ASN C    C N N 132 
ASN O    O N N 133 
ASN CB   C N N 134 
ASN CG   C N N 135 
ASN OD1  O N N 136 
ASN ND2  N N N 137 
ASN OXT  O N N 138 
ASN H    H N N 139 
ASN H2   H N N 140 
ASN HA   H N N 141 
ASN HB2  H N N 142 
ASN HB3  H N N 143 
ASN HD21 H N N 144 
ASN HD22 H N N 145 
ASN HXT  H N N 146 
ASP N    N N N 147 
ASP CA   C N S 148 
ASP C    C N N 149 
ASP O    O N N 150 
ASP CB   C N N 151 
ASP CG   C N N 152 
ASP OD1  O N N 153 
ASP OD2  O N N 154 
ASP OXT  O N N 155 
ASP H    H N N 156 
ASP H2   H N N 157 
ASP HA   H N N 158 
ASP HB2  H N N 159 
ASP HB3  H N N 160 
ASP HD2  H N N 161 
ASP HXT  H N N 162 
COA N1A  N Y N 163 
COA C2A  C Y N 164 
COA N3A  N Y N 165 
COA C4A  C Y N 166 
COA C5A  C Y N 167 
COA C6A  C Y N 168 
COA N6A  N N N 169 
COA N7A  N Y N 170 
COA C8A  C Y N 171 
COA N9A  N Y N 172 
COA C1B  C N R 173 
COA C2B  C N R 174 
COA O2B  O N N 175 
COA C3B  C N S 176 
COA O3B  O N N 177 
COA P3B  P N N 178 
COA O7A  O N N 179 
COA O8A  O N N 180 
COA O9A  O N N 181 
COA C4B  C N R 182 
COA O4B  O N N 183 
COA C5B  C N N 184 
COA O5B  O N N 185 
COA P1A  P N S 186 
COA O1A  O N N 187 
COA O2A  O N N 188 
COA O3A  O N N 189 
COA P2A  P N S 190 
COA O4A  O N N 191 
COA O5A  O N N 192 
COA O6A  O N N 193 
COA CBP  C N N 194 
COA CCP  C N N 195 
COA CDP  C N N 196 
COA CEP  C N N 197 
COA CAP  C N R 198 
COA OAP  O N N 199 
COA C9P  C N N 200 
COA O9P  O N N 201 
COA N8P  N N N 202 
COA C7P  C N N 203 
COA C6P  C N N 204 
COA C5P  C N N 205 
COA O5P  O N N 206 
COA N4P  N N N 207 
COA C3P  C N N 208 
COA C2P  C N N 209 
COA S1P  S N N 210 
COA H2A  H N N 211 
COA H61A H N N 212 
COA H62A H N N 213 
COA H8A  H N N 214 
COA H1B  H N N 215 
COA H2B  H N N 216 
COA HO2A H N N 217 
COA H3B  H N N 218 
COA HOA8 H N N 219 
COA HOA9 H N N 220 
COA H4B  H N N 221 
COA H51A H N N 222 
COA H52A H N N 223 
COA HOA2 H N N 224 
COA HOA5 H N N 225 
COA H121 H N N 226 
COA H122 H N N 227 
COA H131 H N N 228 
COA H132 H N N 229 
COA H133 H N N 230 
COA H141 H N N 231 
COA H142 H N N 232 
COA H143 H N N 233 
COA H10  H N N 234 
COA HO1  H N N 235 
COA HN8  H N N 236 
COA H71  H N N 237 
COA H72  H N N 238 
COA H61  H N N 239 
COA H62  H N N 240 
COA HN4  H N N 241 
COA H31  H N N 242 
COA H32  H N N 243 
COA H21  H N N 244 
COA H22  H N N 245 
COA HS1  H N N 246 
CYS N    N N N 247 
CYS CA   C N R 248 
CYS C    C N N 249 
CYS O    O N N 250 
CYS CB   C N N 251 
CYS SG   S N N 252 
CYS OXT  O N N 253 
CYS H    H N N 254 
CYS H2   H N N 255 
CYS HA   H N N 256 
CYS HB2  H N N 257 
CYS HB3  H N N 258 
CYS HG   H N N 259 
CYS HXT  H N N 260 
GLN N    N N N 261 
GLN CA   C N S 262 
GLN C    C N N 263 
GLN O    O N N 264 
GLN CB   C N N 265 
GLN CG   C N N 266 
GLN CD   C N N 267 
GLN OE1  O N N 268 
GLN NE2  N N N 269 
GLN OXT  O N N 270 
GLN H    H N N 271 
GLN H2   H N N 272 
GLN HA   H N N 273 
GLN HB2  H N N 274 
GLN HB3  H N N 275 
GLN HG2  H N N 276 
GLN HG3  H N N 277 
GLN HE21 H N N 278 
GLN HE22 H N N 279 
GLN HXT  H N N 280 
GLU N    N N N 281 
GLU CA   C N S 282 
GLU C    C N N 283 
GLU O    O N N 284 
GLU CB   C N N 285 
GLU CG   C N N 286 
GLU CD   C N N 287 
GLU OE1  O N N 288 
GLU OE2  O N N 289 
GLU OXT  O N N 290 
GLU H    H N N 291 
GLU H2   H N N 292 
GLU HA   H N N 293 
GLU HB2  H N N 294 
GLU HB3  H N N 295 
GLU HG2  H N N 296 
GLU HG3  H N N 297 
GLU HE2  H N N 298 
GLU HXT  H N N 299 
GLY N    N N N 300 
GLY CA   C N N 301 
GLY C    C N N 302 
GLY O    O N N 303 
GLY OXT  O N N 304 
GLY H    H N N 305 
GLY H2   H N N 306 
GLY HA2  H N N 307 
GLY HA3  H N N 308 
GLY HXT  H N N 309 
HIS N    N N N 310 
HIS CA   C N S 311 
HIS C    C N N 312 
HIS O    O N N 313 
HIS CB   C N N 314 
HIS CG   C Y N 315 
HIS ND1  N Y N 316 
HIS CD2  C Y N 317 
HIS CE1  C Y N 318 
HIS NE2  N Y N 319 
HIS OXT  O N N 320 
HIS H    H N N 321 
HIS H2   H N N 322 
HIS HA   H N N 323 
HIS HB2  H N N 324 
HIS HB3  H N N 325 
HIS HD1  H N N 326 
HIS HD2  H N N 327 
HIS HE1  H N N 328 
HIS HE2  H N N 329 
HIS HXT  H N N 330 
HOH O    O N N 331 
HOH H1   H N N 332 
HOH H2   H N N 333 
ILE N    N N N 334 
ILE CA   C N S 335 
ILE C    C N N 336 
ILE O    O N N 337 
ILE CB   C N S 338 
ILE CG1  C N N 339 
ILE CG2  C N N 340 
ILE CD1  C N N 341 
ILE OXT  O N N 342 
ILE H    H N N 343 
ILE H2   H N N 344 
ILE HA   H N N 345 
ILE HB   H N N 346 
ILE HG12 H N N 347 
ILE HG13 H N N 348 
ILE HG21 H N N 349 
ILE HG22 H N N 350 
ILE HG23 H N N 351 
ILE HD11 H N N 352 
ILE HD12 H N N 353 
ILE HD13 H N N 354 
ILE HXT  H N N 355 
LEU N    N N N 356 
LEU CA   C N S 357 
LEU C    C N N 358 
LEU O    O N N 359 
LEU CB   C N N 360 
LEU CG   C N N 361 
LEU CD1  C N N 362 
LEU CD2  C N N 363 
LEU OXT  O N N 364 
LEU H    H N N 365 
LEU H2   H N N 366 
LEU HA   H N N 367 
LEU HB2  H N N 368 
LEU HB3  H N N 369 
LEU HG   H N N 370 
LEU HD11 H N N 371 
LEU HD12 H N N 372 
LEU HD13 H N N 373 
LEU HD21 H N N 374 
LEU HD22 H N N 375 
LEU HD23 H N N 376 
LEU HXT  H N N 377 
LYS N    N N N 378 
LYS CA   C N S 379 
LYS C    C N N 380 
LYS O    O N N 381 
LYS CB   C N N 382 
LYS CG   C N N 383 
LYS CD   C N N 384 
LYS CE   C N N 385 
LYS NZ   N N N 386 
LYS OXT  O N N 387 
LYS H    H N N 388 
LYS H2   H N N 389 
LYS HA   H N N 390 
LYS HB2  H N N 391 
LYS HB3  H N N 392 
LYS HG2  H N N 393 
LYS HG3  H N N 394 
LYS HD2  H N N 395 
LYS HD3  H N N 396 
LYS HE2  H N N 397 
LYS HE3  H N N 398 
LYS HZ1  H N N 399 
LYS HZ2  H N N 400 
LYS HZ3  H N N 401 
LYS HXT  H N N 402 
MET N    N N N 403 
MET CA   C N S 404 
MET C    C N N 405 
MET O    O N N 406 
MET CB   C N N 407 
MET CG   C N N 408 
MET SD   S N N 409 
MET CE   C N N 410 
MET OXT  O N N 411 
MET H    H N N 412 
MET H2   H N N 413 
MET HA   H N N 414 
MET HB2  H N N 415 
MET HB3  H N N 416 
MET HG2  H N N 417 
MET HG3  H N N 418 
MET HE1  H N N 419 
MET HE2  H N N 420 
MET HE3  H N N 421 
MET HXT  H N N 422 
OAA O1   O N N 423 
OAA O2   O N N 424 
OAA O4   O N N 425 
OAA O5   O N N 426 
OAA O3   O N N 427 
OAA C1   C N N 428 
OAA C2   C N N 429 
OAA C3   C N N 430 
OAA C4   C N N 431 
OAA HO5  H N N 432 
OAA H21  H N N 433 
OAA H22  H N N 434 
PHE N    N N N 435 
PHE CA   C N S 436 
PHE C    C N N 437 
PHE O    O N N 438 
PHE CB   C N N 439 
PHE CG   C Y N 440 
PHE CD1  C Y N 441 
PHE CD2  C Y N 442 
PHE CE1  C Y N 443 
PHE CE2  C Y N 444 
PHE CZ   C Y N 445 
PHE OXT  O N N 446 
PHE H    H N N 447 
PHE H2   H N N 448 
PHE HA   H N N 449 
PHE HB2  H N N 450 
PHE HB3  H N N 451 
PHE HD1  H N N 452 
PHE HD2  H N N 453 
PHE HE1  H N N 454 
PHE HE2  H N N 455 
PHE HZ   H N N 456 
PHE HXT  H N N 457 
PRO N    N N N 458 
PRO CA   C N S 459 
PRO C    C N N 460 
PRO O    O N N 461 
PRO CB   C N N 462 
PRO CG   C N N 463 
PRO CD   C N N 464 
PRO OXT  O N N 465 
PRO H    H N N 466 
PRO HA   H N N 467 
PRO HB2  H N N 468 
PRO HB3  H N N 469 
PRO HG2  H N N 470 
PRO HG3  H N N 471 
PRO HD2  H N N 472 
PRO HD3  H N N 473 
PRO HXT  H N N 474 
SER N    N N N 475 
SER CA   C N S 476 
SER C    C N N 477 
SER O    O N N 478 
SER CB   C N N 479 
SER OG   O N N 480 
SER OXT  O N N 481 
SER H    H N N 482 
SER H2   H N N 483 
SER HA   H N N 484 
SER HB2  H N N 485 
SER HB3  H N N 486 
SER HG   H N N 487 
SER HXT  H N N 488 
THR N    N N N 489 
THR CA   C N S 490 
THR C    C N N 491 
THR O    O N N 492 
THR CB   C N R 493 
THR OG1  O N N 494 
THR CG2  C N N 495 
THR OXT  O N N 496 
THR H    H N N 497 
THR H2   H N N 498 
THR HA   H N N 499 
THR HB   H N N 500 
THR HG1  H N N 501 
THR HG21 H N N 502 
THR HG22 H N N 503 
THR HG23 H N N 504 
THR HXT  H N N 505 
TRP N    N N N 506 
TRP CA   C N S 507 
TRP C    C N N 508 
TRP O    O N N 509 
TRP CB   C N N 510 
TRP CG   C Y N 511 
TRP CD1  C Y N 512 
TRP CD2  C Y N 513 
TRP NE1  N Y N 514 
TRP CE2  C Y N 515 
TRP CE3  C Y N 516 
TRP CZ2  C Y N 517 
TRP CZ3  C Y N 518 
TRP CH2  C Y N 519 
TRP OXT  O N N 520 
TRP H    H N N 521 
TRP H2   H N N 522 
TRP HA   H N N 523 
TRP HB2  H N N 524 
TRP HB3  H N N 525 
TRP HD1  H N N 526 
TRP HE1  H N N 527 
TRP HE3  H N N 528 
TRP HZ2  H N N 529 
TRP HZ3  H N N 530 
TRP HH2  H N N 531 
TRP HXT  H N N 532 
TYR N    N N N 533 
TYR CA   C N S 534 
TYR C    C N N 535 
TYR O    O N N 536 
TYR CB   C N N 537 
TYR CG   C Y N 538 
TYR CD1  C Y N 539 
TYR CD2  C Y N 540 
TYR CE1  C Y N 541 
TYR CE2  C Y N 542 
TYR CZ   C Y N 543 
TYR OH   O N N 544 
TYR OXT  O N N 545 
TYR H    H N N 546 
TYR H2   H N N 547 
TYR HA   H N N 548 
TYR HB2  H N N 549 
TYR HB3  H N N 550 
TYR HD1  H N N 551 
TYR HD2  H N N 552 
TYR HE1  H N N 553 
TYR HE2  H N N 554 
TYR HH   H N N 555 
TYR HXT  H N N 556 
VAL N    N N N 557 
VAL CA   C N S 558 
VAL C    C N N 559 
VAL O    O N N 560 
VAL CB   C N N 561 
VAL CG1  C N N 562 
VAL CG2  C N N 563 
VAL OXT  O N N 564 
VAL H    H N N 565 
VAL H2   H N N 566 
VAL HA   H N N 567 
VAL HB   H N N 568 
VAL HG11 H N N 569 
VAL HG12 H N N 570 
VAL HG13 H N N 571 
VAL HG21 H N N 572 
VAL HG22 H N N 573 
VAL HG23 H N N 574 
VAL HXT  H N N 575 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ACO N1A C2A  sing Y N 1   
ACO N1A C6A  doub Y N 2   
ACO C2A N3A  doub Y N 3   
ACO C2A H2A  sing N N 4   
ACO N3A C4A  sing Y N 5   
ACO C4A C5A  doub Y N 6   
ACO C4A N9A  sing Y N 7   
ACO C5A C6A  sing Y N 8   
ACO C5A N7A  sing Y N 9   
ACO C6A N6A  sing N N 10  
ACO N6A H61A sing N N 11  
ACO N6A H62A sing N N 12  
ACO N7A C8A  doub Y N 13  
ACO C8A N9A  sing Y N 14  
ACO C8A H8A  sing N N 15  
ACO N9A C1B  sing N N 16  
ACO C1B C2B  sing N N 17  
ACO C1B O4B  sing N N 18  
ACO C1B H1B  sing N N 19  
ACO C2B O2B  sing N N 20  
ACO C2B C3B  sing N N 21  
ACO C2B H2B  sing N N 22  
ACO O2B HO2A sing N N 23  
ACO C3B O3B  sing N N 24  
ACO C3B C4B  sing N N 25  
ACO C3B H3B  sing N N 26  
ACO O3B P3B  sing N N 27  
ACO P3B O7A  doub N N 28  
ACO P3B O8A  sing N N 29  
ACO P3B O9A  sing N N 30  
ACO O8A HOA8 sing N N 31  
ACO O9A HOA9 sing N N 32  
ACO C4B O4B  sing N N 33  
ACO C4B C5B  sing N N 34  
ACO C4B H4B  sing N N 35  
ACO C5B O5B  sing N N 36  
ACO C5B H51A sing N N 37  
ACO C5B H52A sing N N 38  
ACO O5B P1A  sing N N 39  
ACO P1A O1A  doub N N 40  
ACO P1A O2A  sing N N 41  
ACO P1A O3A  sing N N 42  
ACO O2A HOA2 sing N N 43  
ACO O3A P2A  sing N N 44  
ACO P2A O4A  doub N N 45  
ACO P2A O5A  sing N N 46  
ACO P2A O6A  sing N N 47  
ACO O5A HOA5 sing N N 48  
ACO O6A CCP  sing N N 49  
ACO CBP CCP  sing N N 50  
ACO CBP CDP  sing N N 51  
ACO CBP CEP  sing N N 52  
ACO CBP CAP  sing N N 53  
ACO CCP H121 sing N N 54  
ACO CCP H122 sing N N 55  
ACO CDP H131 sing N N 56  
ACO CDP H132 sing N N 57  
ACO CDP H133 sing N N 58  
ACO CEP H141 sing N N 59  
ACO CEP H142 sing N N 60  
ACO CEP H143 sing N N 61  
ACO CAP OAP  sing N N 62  
ACO CAP C9P  sing N N 63  
ACO CAP H10  sing N N 64  
ACO OAP HO1  sing N N 65  
ACO C9P O9P  doub N N 66  
ACO C9P N8P  sing N N 67  
ACO N8P C7P  sing N N 68  
ACO N8P HN8  sing N N 69  
ACO C7P C6P  sing N N 70  
ACO C7P H71  sing N N 71  
ACO C7P H72  sing N N 72  
ACO C6P C5P  sing N N 73  
ACO C6P H61  sing N N 74  
ACO C6P H62  sing N N 75  
ACO C5P O5P  doub N N 76  
ACO C5P N4P  sing N N 77  
ACO N4P C3P  sing N N 78  
ACO N4P HN4  sing N N 79  
ACO C3P C2P  sing N N 80  
ACO C3P H31  sing N N 81  
ACO C3P H32  sing N N 82  
ACO C2P S1P  sing N N 83  
ACO C2P H21  sing N N 84  
ACO C2P H22  sing N N 85  
ACO S1P C    sing N N 86  
ACO C   O    doub N N 87  
ACO C   CH3  sing N N 88  
ACO CH3 HH31 sing N N 89  
ACO CH3 HH32 sing N N 90  
ACO CH3 HH33 sing N N 91  
ALA N   CA   sing N N 92  
ALA N   H    sing N N 93  
ALA N   H2   sing N N 94  
ALA CA  C    sing N N 95  
ALA CA  CB   sing N N 96  
ALA CA  HA   sing N N 97  
ALA C   O    doub N N 98  
ALA C   OXT  sing N N 99  
ALA CB  HB1  sing N N 100 
ALA CB  HB2  sing N N 101 
ALA CB  HB3  sing N N 102 
ALA OXT HXT  sing N N 103 
ARG N   CA   sing N N 104 
ARG N   H    sing N N 105 
ARG N   H2   sing N N 106 
ARG CA  C    sing N N 107 
ARG CA  CB   sing N N 108 
ARG CA  HA   sing N N 109 
ARG C   O    doub N N 110 
ARG C   OXT  sing N N 111 
ARG CB  CG   sing N N 112 
ARG CB  HB2  sing N N 113 
ARG CB  HB3  sing N N 114 
ARG CG  CD   sing N N 115 
ARG CG  HG2  sing N N 116 
ARG CG  HG3  sing N N 117 
ARG CD  NE   sing N N 118 
ARG CD  HD2  sing N N 119 
ARG CD  HD3  sing N N 120 
ARG NE  CZ   sing N N 121 
ARG NE  HE   sing N N 122 
ARG CZ  NH1  sing N N 123 
ARG CZ  NH2  doub N N 124 
ARG NH1 HH11 sing N N 125 
ARG NH1 HH12 sing N N 126 
ARG NH2 HH21 sing N N 127 
ARG NH2 HH22 sing N N 128 
ARG OXT HXT  sing N N 129 
ASN N   CA   sing N N 130 
ASN N   H    sing N N 131 
ASN N   H2   sing N N 132 
ASN CA  C    sing N N 133 
ASN CA  CB   sing N N 134 
ASN CA  HA   sing N N 135 
ASN C   O    doub N N 136 
ASN C   OXT  sing N N 137 
ASN CB  CG   sing N N 138 
ASN CB  HB2  sing N N 139 
ASN CB  HB3  sing N N 140 
ASN CG  OD1  doub N N 141 
ASN CG  ND2  sing N N 142 
ASN ND2 HD21 sing N N 143 
ASN ND2 HD22 sing N N 144 
ASN OXT HXT  sing N N 145 
ASP N   CA   sing N N 146 
ASP N   H    sing N N 147 
ASP N   H2   sing N N 148 
ASP CA  C    sing N N 149 
ASP CA  CB   sing N N 150 
ASP CA  HA   sing N N 151 
ASP C   O    doub N N 152 
ASP C   OXT  sing N N 153 
ASP CB  CG   sing N N 154 
ASP CB  HB2  sing N N 155 
ASP CB  HB3  sing N N 156 
ASP CG  OD1  doub N N 157 
ASP CG  OD2  sing N N 158 
ASP OD2 HD2  sing N N 159 
ASP OXT HXT  sing N N 160 
COA N1A C2A  sing Y N 161 
COA N1A C6A  doub Y N 162 
COA C2A N3A  doub Y N 163 
COA C2A H2A  sing N N 164 
COA N3A C4A  sing Y N 165 
COA C4A C5A  doub Y N 166 
COA C4A N9A  sing Y N 167 
COA C5A C6A  sing Y N 168 
COA C5A N7A  sing Y N 169 
COA C6A N6A  sing N N 170 
COA N6A H61A sing N N 171 
COA N6A H62A sing N N 172 
COA N7A C8A  doub Y N 173 
COA C8A N9A  sing Y N 174 
COA C8A H8A  sing N N 175 
COA N9A C1B  sing N N 176 
COA C1B C2B  sing N N 177 
COA C1B O4B  sing N N 178 
COA C1B H1B  sing N N 179 
COA C2B O2B  sing N N 180 
COA C2B C3B  sing N N 181 
COA C2B H2B  sing N N 182 
COA O2B HO2A sing N N 183 
COA C3B O3B  sing N N 184 
COA C3B C4B  sing N N 185 
COA C3B H3B  sing N N 186 
COA O3B P3B  sing N N 187 
COA P3B O7A  doub N N 188 
COA P3B O8A  sing N N 189 
COA P3B O9A  sing N N 190 
COA O8A HOA8 sing N N 191 
COA O9A HOA9 sing N N 192 
COA C4B O4B  sing N N 193 
COA C4B C5B  sing N N 194 
COA C4B H4B  sing N N 195 
COA C5B O5B  sing N N 196 
COA C5B H51A sing N N 197 
COA C5B H52A sing N N 198 
COA O5B P1A  sing N N 199 
COA P1A O1A  doub N N 200 
COA P1A O2A  sing N N 201 
COA P1A O3A  sing N N 202 
COA O2A HOA2 sing N N 203 
COA O3A P2A  sing N N 204 
COA P2A O4A  doub N N 205 
COA P2A O5A  sing N N 206 
COA P2A O6A  sing N N 207 
COA O5A HOA5 sing N N 208 
COA O6A CCP  sing N N 209 
COA CBP CCP  sing N N 210 
COA CBP CDP  sing N N 211 
COA CBP CEP  sing N N 212 
COA CBP CAP  sing N N 213 
COA CCP H121 sing N N 214 
COA CCP H122 sing N N 215 
COA CDP H131 sing N N 216 
COA CDP H132 sing N N 217 
COA CDP H133 sing N N 218 
COA CEP H141 sing N N 219 
COA CEP H142 sing N N 220 
COA CEP H143 sing N N 221 
COA CAP OAP  sing N N 222 
COA CAP C9P  sing N N 223 
COA CAP H10  sing N N 224 
COA OAP HO1  sing N N 225 
COA C9P O9P  doub N N 226 
COA C9P N8P  sing N N 227 
COA N8P C7P  sing N N 228 
COA N8P HN8  sing N N 229 
COA C7P C6P  sing N N 230 
COA C7P H71  sing N N 231 
COA C7P H72  sing N N 232 
COA C6P C5P  sing N N 233 
COA C6P H61  sing N N 234 
COA C6P H62  sing N N 235 
COA C5P O5P  doub N N 236 
COA C5P N4P  sing N N 237 
COA N4P C3P  sing N N 238 
COA N4P HN4  sing N N 239 
COA C3P C2P  sing N N 240 
COA C3P H31  sing N N 241 
COA C3P H32  sing N N 242 
COA C2P S1P  sing N N 243 
COA C2P H21  sing N N 244 
COA C2P H22  sing N N 245 
COA S1P HS1  sing N N 246 
CYS N   CA   sing N N 247 
CYS N   H    sing N N 248 
CYS N   H2   sing N N 249 
CYS CA  C    sing N N 250 
CYS CA  CB   sing N N 251 
CYS CA  HA   sing N N 252 
CYS C   O    doub N N 253 
CYS C   OXT  sing N N 254 
CYS CB  SG   sing N N 255 
CYS CB  HB2  sing N N 256 
CYS CB  HB3  sing N N 257 
CYS SG  HG   sing N N 258 
CYS OXT HXT  sing N N 259 
GLN N   CA   sing N N 260 
GLN N   H    sing N N 261 
GLN N   H2   sing N N 262 
GLN CA  C    sing N N 263 
GLN CA  CB   sing N N 264 
GLN CA  HA   sing N N 265 
GLN C   O    doub N N 266 
GLN C   OXT  sing N N 267 
GLN CB  CG   sing N N 268 
GLN CB  HB2  sing N N 269 
GLN CB  HB3  sing N N 270 
GLN CG  CD   sing N N 271 
GLN CG  HG2  sing N N 272 
GLN CG  HG3  sing N N 273 
GLN CD  OE1  doub N N 274 
GLN CD  NE2  sing N N 275 
GLN NE2 HE21 sing N N 276 
GLN NE2 HE22 sing N N 277 
GLN OXT HXT  sing N N 278 
GLU N   CA   sing N N 279 
GLU N   H    sing N N 280 
GLU N   H2   sing N N 281 
GLU CA  C    sing N N 282 
GLU CA  CB   sing N N 283 
GLU CA  HA   sing N N 284 
GLU C   O    doub N N 285 
GLU C   OXT  sing N N 286 
GLU CB  CG   sing N N 287 
GLU CB  HB2  sing N N 288 
GLU CB  HB3  sing N N 289 
GLU CG  CD   sing N N 290 
GLU CG  HG2  sing N N 291 
GLU CG  HG3  sing N N 292 
GLU CD  OE1  doub N N 293 
GLU CD  OE2  sing N N 294 
GLU OE2 HE2  sing N N 295 
GLU OXT HXT  sing N N 296 
GLY N   CA   sing N N 297 
GLY N   H    sing N N 298 
GLY N   H2   sing N N 299 
GLY CA  C    sing N N 300 
GLY CA  HA2  sing N N 301 
GLY CA  HA3  sing N N 302 
GLY C   O    doub N N 303 
GLY C   OXT  sing N N 304 
GLY OXT HXT  sing N N 305 
HIS N   CA   sing N N 306 
HIS N   H    sing N N 307 
HIS N   H2   sing N N 308 
HIS CA  C    sing N N 309 
HIS CA  CB   sing N N 310 
HIS CA  HA   sing N N 311 
HIS C   O    doub N N 312 
HIS C   OXT  sing N N 313 
HIS CB  CG   sing N N 314 
HIS CB  HB2  sing N N 315 
HIS CB  HB3  sing N N 316 
HIS CG  ND1  sing Y N 317 
HIS CG  CD2  doub Y N 318 
HIS ND1 CE1  doub Y N 319 
HIS ND1 HD1  sing N N 320 
HIS CD2 NE2  sing Y N 321 
HIS CD2 HD2  sing N N 322 
HIS CE1 NE2  sing Y N 323 
HIS CE1 HE1  sing N N 324 
HIS NE2 HE2  sing N N 325 
HIS OXT HXT  sing N N 326 
HOH O   H1   sing N N 327 
HOH O   H2   sing N N 328 
ILE N   CA   sing N N 329 
ILE N   H    sing N N 330 
ILE N   H2   sing N N 331 
ILE CA  C    sing N N 332 
ILE CA  CB   sing N N 333 
ILE CA  HA   sing N N 334 
ILE C   O    doub N N 335 
ILE C   OXT  sing N N 336 
ILE CB  CG1  sing N N 337 
ILE CB  CG2  sing N N 338 
ILE CB  HB   sing N N 339 
ILE CG1 CD1  sing N N 340 
ILE CG1 HG12 sing N N 341 
ILE CG1 HG13 sing N N 342 
ILE CG2 HG21 sing N N 343 
ILE CG2 HG22 sing N N 344 
ILE CG2 HG23 sing N N 345 
ILE CD1 HD11 sing N N 346 
ILE CD1 HD12 sing N N 347 
ILE CD1 HD13 sing N N 348 
ILE OXT HXT  sing N N 349 
LEU N   CA   sing N N 350 
LEU N   H    sing N N 351 
LEU N   H2   sing N N 352 
LEU CA  C    sing N N 353 
LEU CA  CB   sing N N 354 
LEU CA  HA   sing N N 355 
LEU C   O    doub N N 356 
LEU C   OXT  sing N N 357 
LEU CB  CG   sing N N 358 
LEU CB  HB2  sing N N 359 
LEU CB  HB3  sing N N 360 
LEU CG  CD1  sing N N 361 
LEU CG  CD2  sing N N 362 
LEU CG  HG   sing N N 363 
LEU CD1 HD11 sing N N 364 
LEU CD1 HD12 sing N N 365 
LEU CD1 HD13 sing N N 366 
LEU CD2 HD21 sing N N 367 
LEU CD2 HD22 sing N N 368 
LEU CD2 HD23 sing N N 369 
LEU OXT HXT  sing N N 370 
LYS N   CA   sing N N 371 
LYS N   H    sing N N 372 
LYS N   H2   sing N N 373 
LYS CA  C    sing N N 374 
LYS CA  CB   sing N N 375 
LYS CA  HA   sing N N 376 
LYS C   O    doub N N 377 
LYS C   OXT  sing N N 378 
LYS CB  CG   sing N N 379 
LYS CB  HB2  sing N N 380 
LYS CB  HB3  sing N N 381 
LYS CG  CD   sing N N 382 
LYS CG  HG2  sing N N 383 
LYS CG  HG3  sing N N 384 
LYS CD  CE   sing N N 385 
LYS CD  HD2  sing N N 386 
LYS CD  HD3  sing N N 387 
LYS CE  NZ   sing N N 388 
LYS CE  HE2  sing N N 389 
LYS CE  HE3  sing N N 390 
LYS NZ  HZ1  sing N N 391 
LYS NZ  HZ2  sing N N 392 
LYS NZ  HZ3  sing N N 393 
LYS OXT HXT  sing N N 394 
MET N   CA   sing N N 395 
MET N   H    sing N N 396 
MET N   H2   sing N N 397 
MET CA  C    sing N N 398 
MET CA  CB   sing N N 399 
MET CA  HA   sing N N 400 
MET C   O    doub N N 401 
MET C   OXT  sing N N 402 
MET CB  CG   sing N N 403 
MET CB  HB2  sing N N 404 
MET CB  HB3  sing N N 405 
MET CG  SD   sing N N 406 
MET CG  HG2  sing N N 407 
MET CG  HG3  sing N N 408 
MET SD  CE   sing N N 409 
MET CE  HE1  sing N N 410 
MET CE  HE2  sing N N 411 
MET CE  HE3  sing N N 412 
MET OXT HXT  sing N N 413 
OAA O1  C1   doub N N 414 
OAA O2  C1   sing N N 415 
OAA O4  C4   doub N N 416 
OAA O5  C4   sing N N 417 
OAA O5  HO5  sing N N 418 
OAA O3  C3   doub N N 419 
OAA C1  C2   sing N N 420 
OAA C2  C3   sing N N 421 
OAA C2  H21  sing N N 422 
OAA C2  H22  sing N N 423 
OAA C3  C4   sing N N 424 
PHE N   CA   sing N N 425 
PHE N   H    sing N N 426 
PHE N   H2   sing N N 427 
PHE CA  C    sing N N 428 
PHE CA  CB   sing N N 429 
PHE CA  HA   sing N N 430 
PHE C   O    doub N N 431 
PHE C   OXT  sing N N 432 
PHE CB  CG   sing N N 433 
PHE CB  HB2  sing N N 434 
PHE CB  HB3  sing N N 435 
PHE CG  CD1  doub Y N 436 
PHE CG  CD2  sing Y N 437 
PHE CD1 CE1  sing Y N 438 
PHE CD1 HD1  sing N N 439 
PHE CD2 CE2  doub Y N 440 
PHE CD2 HD2  sing N N 441 
PHE CE1 CZ   doub Y N 442 
PHE CE1 HE1  sing N N 443 
PHE CE2 CZ   sing Y N 444 
PHE CE2 HE2  sing N N 445 
PHE CZ  HZ   sing N N 446 
PHE OXT HXT  sing N N 447 
PRO N   CA   sing N N 448 
PRO N   CD   sing N N 449 
PRO N   H    sing N N 450 
PRO CA  C    sing N N 451 
PRO CA  CB   sing N N 452 
PRO CA  HA   sing N N 453 
PRO C   O    doub N N 454 
PRO C   OXT  sing N N 455 
PRO CB  CG   sing N N 456 
PRO CB  HB2  sing N N 457 
PRO CB  HB3  sing N N 458 
PRO CG  CD   sing N N 459 
PRO CG  HG2  sing N N 460 
PRO CG  HG3  sing N N 461 
PRO CD  HD2  sing N N 462 
PRO CD  HD3  sing N N 463 
PRO OXT HXT  sing N N 464 
SER N   CA   sing N N 465 
SER N   H    sing N N 466 
SER N   H2   sing N N 467 
SER CA  C    sing N N 468 
SER CA  CB   sing N N 469 
SER CA  HA   sing N N 470 
SER C   O    doub N N 471 
SER C   OXT  sing N N 472 
SER CB  OG   sing N N 473 
SER CB  HB2  sing N N 474 
SER CB  HB3  sing N N 475 
SER OG  HG   sing N N 476 
SER OXT HXT  sing N N 477 
THR N   CA   sing N N 478 
THR N   H    sing N N 479 
THR N   H2   sing N N 480 
THR CA  C    sing N N 481 
THR CA  CB   sing N N 482 
THR CA  HA   sing N N 483 
THR C   O    doub N N 484 
THR C   OXT  sing N N 485 
THR CB  OG1  sing N N 486 
THR CB  CG2  sing N N 487 
THR CB  HB   sing N N 488 
THR OG1 HG1  sing N N 489 
THR CG2 HG21 sing N N 490 
THR CG2 HG22 sing N N 491 
THR CG2 HG23 sing N N 492 
THR OXT HXT  sing N N 493 
TRP N   CA   sing N N 494 
TRP N   H    sing N N 495 
TRP N   H2   sing N N 496 
TRP CA  C    sing N N 497 
TRP CA  CB   sing N N 498 
TRP CA  HA   sing N N 499 
TRP C   O    doub N N 500 
TRP C   OXT  sing N N 501 
TRP CB  CG   sing N N 502 
TRP CB  HB2  sing N N 503 
TRP CB  HB3  sing N N 504 
TRP CG  CD1  doub Y N 505 
TRP CG  CD2  sing Y N 506 
TRP CD1 NE1  sing Y N 507 
TRP CD1 HD1  sing N N 508 
TRP CD2 CE2  doub Y N 509 
TRP CD2 CE3  sing Y N 510 
TRP NE1 CE2  sing Y N 511 
TRP NE1 HE1  sing N N 512 
TRP CE2 CZ2  sing Y N 513 
TRP CE3 CZ3  doub Y N 514 
TRP CE3 HE3  sing N N 515 
TRP CZ2 CH2  doub Y N 516 
TRP CZ2 HZ2  sing N N 517 
TRP CZ3 CH2  sing Y N 518 
TRP CZ3 HZ3  sing N N 519 
TRP CH2 HH2  sing N N 520 
TRP OXT HXT  sing N N 521 
TYR N   CA   sing N N 522 
TYR N   H    sing N N 523 
TYR N   H2   sing N N 524 
TYR CA  C    sing N N 525 
TYR CA  CB   sing N N 526 
TYR CA  HA   sing N N 527 
TYR C   O    doub N N 528 
TYR C   OXT  sing N N 529 
TYR CB  CG   sing N N 530 
TYR CB  HB2  sing N N 531 
TYR CB  HB3  sing N N 532 
TYR CG  CD1  doub Y N 533 
TYR CG  CD2  sing Y N 534 
TYR CD1 CE1  sing Y N 535 
TYR CD1 HD1  sing N N 536 
TYR CD2 CE2  doub Y N 537 
TYR CD2 HD2  sing N N 538 
TYR CE1 CZ   doub Y N 539 
TYR CE1 HE1  sing N N 540 
TYR CE2 CZ   sing Y N 541 
TYR CE2 HE2  sing N N 542 
TYR CZ  OH   sing N N 543 
TYR OH  HH   sing N N 544 
TYR OXT HXT  sing N N 545 
VAL N   CA   sing N N 546 
VAL N   H    sing N N 547 
VAL N   H2   sing N N 548 
VAL CA  C    sing N N 549 
VAL CA  CB   sing N N 550 
VAL CA  HA   sing N N 551 
VAL C   O    doub N N 552 
VAL C   OXT  sing N N 553 
VAL CB  CG1  sing N N 554 
VAL CB  CG2  sing N N 555 
VAL CB  HB   sing N N 556 
VAL CG1 HG11 sing N N 557 
VAL CG1 HG12 sing N N 558 
VAL CG1 HG13 sing N N 559 
VAL CG2 HG21 sing N N 560 
VAL CG2 HG22 sing N N 561 
VAL CG2 HG23 sing N N 562 
VAL OXT HXT  sing N N 563 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   A0A0S3QTD0 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8XXF 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009217 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007590 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004825 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . MET A 1 1   ? 11.550  39.110  -7.756  1.00 54.59  ? 1   MET A N   1 
ATOM   2     C CA  . MET A 1 1   ? 11.766  37.963  -6.839  1.00 50.42  ? 1   MET A CA  1 
ATOM   3     C C   . MET A 1 1   ? 10.787  36.863  -7.238  1.00 49.37  ? 1   MET A C   1 
ATOM   4     O O   . MET A 1 1   ? 9.596   37.118  -7.372  1.00 42.60  ? 1   MET A O   1 
ATOM   5     C CB  . MET A 1 1   ? 11.554  38.392  -5.383  1.00 47.07  ? 1   MET A CB  1 
ATOM   6     C CG  . MET A 1 1   ? 11.739  37.260  -4.402  1.00 48.87  ? 1   MET A CG  1 
ATOM   7     S SD  . MET A 1 1   ? 11.574  37.702  -2.657  1.00 53.04  ? 1   MET A SD  1 
ATOM   8     C CE  . MET A 1 1   ? 10.520  39.156  -2.755  1.00 55.59  ? 1   MET A CE  1 
ATOM   9     N N   . LYS A 1 2   ? 11.310  35.655  -7.463  1.00 50.17  ? 2   LYS A N   1 
ATOM   10    C CA  . LYS A 1 2   ? 10.504  34.494  -7.801  1.00 54.30  ? 2   LYS A CA  1 
ATOM   11    C C   . LYS A 1 2   ? 9.345   34.335  -6.807  1.00 49.38  ? 2   LYS A C   1 
ATOM   12    O O   . LYS A 1 2   ? 8.194   34.147  -7.205  1.00 49.82  ? 2   LYS A O   1 
ATOM   13    C CB  . LYS A 1 2   ? 11.442  33.281  -7.847  1.00 57.95  ? 2   LYS A CB  1 
ATOM   14    C CG  . LYS A 1 2   ? 10.816  31.922  -8.137  1.00 62.57  ? 2   LYS A CG  1 
ATOM   15    C CD  . LYS A 1 2   ? 10.327  31.714  -9.565  1.00 64.25  ? 2   LYS A CD  1 
ATOM   16    C CE  . LYS A 1 2   ? 10.165  30.247  -9.819  1.00 67.15  ? 2   LYS A CE  1 
ATOM   17    N NZ  . LYS A 1 2   ? 8.916   29.966  -10.534 1.00 68.65  ? 2   LYS A NZ  1 
ATOM   18    N N   . LEU A 1 3   ? 9.642   34.407  -5.509  1.00 46.11  ? 3   LEU A N   1 
ATOM   19    C CA  . LEU A 1 3   ? 8.638   34.155  -4.488  1.00 42.77  ? 3   LEU A CA  1 
ATOM   20    C C   . LEU A 1 3   ? 7.376   34.986  -4.760  1.00 40.06  ? 3   LEU A C   1 
ATOM   21    O O   . LEU A 1 3   ? 6.273   34.465  -4.706  1.00 38.64  ? 3   LEU A O   1 
ATOM   22    C CB  . LEU A 1 3   ? 9.219   34.396  -3.093  1.00 38.77  ? 3   LEU A CB  1 
ATOM   23    C CG  . LEU A 1 3   ? 8.196   34.409  -1.953  1.00 39.92  ? 3   LEU A CG  1 
ATOM   24    C CD1 . LEU A 1 3   ? 7.589   33.030  -1.831  1.00 39.34  ? 3   LEU A CD1 1 
ATOM   25    C CD2 . LEU A 1 3   ? 8.775   34.882  -0.616  1.00 41.36  ? 3   LEU A CD2 1 
ATOM   26    N N   . LYS A 1 4   ? 7.515   36.277  -5.069  1.00 38.01  ? 4   LYS A N   1 
ATOM   27    C CA  . LYS A 1 4   ? 6.346   37.122  -5.246  1.00 39.67  ? 4   LYS A CA  1 
ATOM   28    C C   . LYS A 1 4   ? 5.587   36.728  -6.514  1.00 43.71  ? 4   LYS A C   1 
ATOM   29    O O   . LYS A 1 4   ? 4.356   36.693  -6.523  1.00 42.86  ? 4   LYS A O   1 
ATOM   30    C CB  . LYS A 1 4   ? 6.726   38.609  -5.261  1.00 42.00  ? 4   LYS A CB  1 
ATOM   31    C CG  . LYS A 1 4   ? 5.521   39.537  -5.339  1.00 42.83  ? 4   LYS A CG  1 
ATOM   32    C CD  . LYS A 1 4   ? 5.793   41.020  -5.105  1.00 44.44  ? 4   LYS A CD  1 
ATOM   33    C CE  . LYS A 1 4   ? 4.604   41.861  -5.484  1.00 45.18  ? 4   LYS A CE  1 
ATOM   34    N NZ  . LYS A 1 4   ? 4.516   43.079  -4.675  1.00 47.10  ? 4   LYS A NZ  1 
ATOM   35    N N   . GLU A 1 5   ? 6.323   36.441  -7.591  1.00 49.22  ? 5   GLU A N   1 
ATOM   36    C CA  . GLU A 1 5   ? 5.717   36.113  -8.877  1.00 50.69  ? 5   GLU A CA  1 
ATOM   37    C C   . GLU A 1 5   ? 4.792   34.909  -8.731  1.00 44.39  ? 5   GLU A C   1 
ATOM   38    O O   . GLU A 1 5   ? 3.675   34.923  -9.225  1.00 43.48  ? 5   GLU A O   1 
ATOM   39    C CB  . GLU A 1 5   ? 6.799   35.871  -9.931  1.00 49.58  ? 5   GLU A CB  1 
ATOM   40    C CG  . GLU A 1 5   ? 7.362   37.172  -10.497 1.00 50.45  ? 5   GLU A CG  1 
ATOM   41    C CD  . GLU A 1 5   ? 8.741   37.062  -11.131 1.00 52.69  ? 5   GLU A CD  1 
ATOM   42    O OE1 . GLU A 1 5   ? 9.245   38.128  -11.570 1.00 55.46  ? 5   GLU A OE1 1 
ATOM   43    O OE2 . GLU A 1 5   ? 9.329   35.953  -11.175 1.00 52.68  ? 5   GLU A OE2 1 
ATOM   44    N N   . ARG A 1 6   ? 5.274   33.896  -8.014  1.00 46.85  ? 6   ARG A N   1 
ATOM   45    C CA  . ARG A 1 6   ? 4.560   32.652  -7.767  1.00 47.90  ? 6   ARG A CA  1 
ATOM   46    C C   . ARG A 1 6   ? 3.341   32.905  -6.883  1.00 45.11  ? 6   ARG A C   1 
ATOM   47    O O   . ARG A 1 6   ? 2.284   32.333  -7.085  1.00 45.35  ? 6   ARG A O   1 
ATOM   48    C CB  . ARG A 1 6   ? 5.554   31.721  -7.068  1.00 52.37  ? 6   ARG A CB  1 
ATOM   49    C CG  . ARG A 1 6   ? 5.238   30.247  -7.208  1.00 58.01  ? 6   ARG A CG  1 
ATOM   50    C CD  . ARG A 1 6   ? 5.687   29.725  -8.565  1.00 59.58  ? 6   ARG A CD  1 
ATOM   51    N NE  . ARG A 1 6   ? 4.740   28.655  -8.886  1.00 57.40  ? 6   ARG A NE  1 
ATOM   52    C CZ  . ARG A 1 6   ? 3.525   28.884  -9.349  1.00 58.93  ? 6   ARG A CZ  1 
ATOM   53    N NH1 . ARG A 1 6   ? 3.258   30.000  -10.001 1.00 58.54  ? 6   ARG A NH1 1 
ATOM   54    N NH2 . ARG A 1 6   ? 2.592   27.964  -9.232  1.00 64.93  ? 6   ARG A NH2 1 
ATOM   55    N N   . LEU A 1 7   ? 3.489   33.785  -5.891  1.00 47.01  ? 7   LEU A N   1 
ATOM   56    C CA  . LEU A 1 7   ? 2.361   34.181  -5.067  1.00 44.96  ? 7   LEU A CA  1 
ATOM   57    C C   . LEU A 1 7   ? 1.330   34.954  -5.896  1.00 44.75  ? 7   LEU A C   1 
ATOM   58    O O   . LEU A 1 7   ? 0.131   34.806  -5.648  1.00 41.86  ? 7   LEU A O   1 
ATOM   59    C CB  . LEU A 1 7   ? 2.851   34.983  -3.860  1.00 39.77  ? 7   LEU A CB  1 
ATOM   60    C CG  . LEU A 1 7   ? 3.523   34.179  -2.748  1.00 37.92  ? 7   LEU A CG  1 
ATOM   61    C CD1 . LEU A 1 7   ? 4.110   35.145  -1.738  1.00 40.65  ? 7   LEU A CD1 1 
ATOM   62    C CD2 . LEU A 1 7   ? 2.589   33.225  -2.038  1.00 34.98  ? 7   LEU A CD2 1 
ATOM   63    N N   . ALA A 1 8   ? 1.797   35.788  -6.851  1.00 43.79  ? 8   ALA A N   1 
ATOM   64    C CA  . ALA A 1 8   ? 0.924   36.621  -7.677  1.00 43.32  ? 8   ALA A CA  1 
ATOM   65    C C   . ALA A 1 8   ? 0.033   35.747  -8.576  1.00 41.56  ? 8   ALA A C   1 
ATOM   66    O O   . ALA A 1 8   ? -1.048  36.162  -8.976  1.00 32.02  ? 8   ALA A O   1 
ATOM   67    C CB  . ALA A 1 8   ? 1.759   37.619  -8.478  1.00 41.59  ? 8   ALA A CB  1 
ATOM   68    N N   . GLU A 1 9   ? 0.485   34.516  -8.859  1.00 43.36  ? 9   GLU A N   1 
ATOM   69    C CA  . GLU A 1 9   ? -0.354  33.505  -9.484  1.00 50.95  ? 9   GLU A CA  1 
ATOM   70    C C   . GLU A 1 9   ? -1.181  32.752  -8.448  1.00 47.28  ? 9   GLU A C   1 
ATOM   71    O O   . GLU A 1 9   ? -2.379  32.585  -8.626  1.00 50.50  ? 9   GLU A O   1 
ATOM   72    C CB  . GLU A 1 9   ? 0.462   32.454  -10.229 1.00 55.36  ? 9   GLU A CB  1 
ATOM   73    C CG  . GLU A 1 9   ? 1.007   32.972  -11.554 1.00 66.51  ? 9   GLU A CG  1 
ATOM   74    C CD  . GLU A 1 9   ? 1.699   31.900  -12.372 1.00 78.85  ? 9   GLU A CD  1 
ATOM   75    O OE1 . GLU A 1 9   ? 2.787   32.231  -12.903 1.00 84.98  ? 9   GLU A OE1 1 
ATOM   76    O OE2 . GLU A 1 9   ? 1.167   30.755  -12.455 1.00 76.14  ? 9   GLU A OE2 1 
ATOM   77    N N   . LEU A 1 10  ? -0.536  32.271  -7.383  1.00 40.89  ? 10  LEU A N   1 
ATOM   78    C CA  . LEU A 1 10  ? -1.164  31.283  -6.530  1.00 39.37  ? 10  LEU A CA  1 
ATOM   79    C C   . LEU A 1 10  ? -2.299  31.900  -5.712  1.00 38.76  ? 10  LEU A C   1 
ATOM   80    O O   . LEU A 1 10  ? -3.348  31.276  -5.575  1.00 34.05  ? 10  LEU A O   1 
ATOM   81    C CB  . LEU A 1 10  ? -0.142  30.581  -5.636  1.00 37.29  ? 10  LEU A CB  1 
ATOM   82    C CG  . LEU A 1 10  ? 0.752   29.522  -6.292  1.00 36.00  ? 10  LEU A CG  1 
ATOM   83    C CD1 . LEU A 1 10  ? 1.930   29.170  -5.366  1.00 34.28  ? 10  LEU A CD1 1 
ATOM   84    C CD2 . LEU A 1 10  ? -0.010  28.269  -6.646  1.00 33.04  ? 10  LEU A CD2 1 
ATOM   85    N N   . ILE A 1 11  ? -2.096  33.105  -5.162  1.00 40.05  ? 11  ILE A N   1 
ATOM   86    C CA  . ILE A 1 11  ? -3.018  33.648  -4.166  1.00 43.76  ? 11  ILE A CA  1 
ATOM   87    C C   . ILE A 1 11  ? -4.415  33.912  -4.744  1.00 42.95  ? 11  ILE A C   1 
ATOM   88    O O   . ILE A 1 11  ? -5.420  33.510  -4.143  1.00 38.81  ? 11  ILE A O   1 
ATOM   89    C CB  . ILE A 1 11  ? -2.413  34.885  -3.481  1.00 44.75  ? 11  ILE A CB  1 
ATOM   90    C CG1 . ILE A 1 11  ? -1.425  34.426  -2.376  1.00 44.33  ? 11  ILE A CG1 1 
ATOM   91    C CG2 . ILE A 1 11  ? -3.514  35.817  -2.953  1.00 43.58  ? 11  ILE A CG2 1 
ATOM   92    C CD1 . ILE A 1 11  ? -0.537  35.516  -1.794  1.00 43.53  ? 11  ILE A CD1 1 
ATOM   93    N N   . PRO A 1 12  ? -4.557  34.587  -5.911  1.00 41.08  ? 12  PRO A N   1 
ATOM   94    C CA  . PRO A 1 12  ? -5.865  34.673  -6.561  1.00 41.56  ? 12  PRO A CA  1 
ATOM   95    C C   . PRO A 1 12  ? -6.594  33.335  -6.735  1.00 39.66  ? 12  PRO A C   1 
ATOM   96    O O   . PRO A 1 12  ? -7.813  33.278  -6.610  1.00 42.71  ? 12  PRO A O   1 
ATOM   97    C CB  . PRO A 1 12  ? -5.520  35.342  -7.900  1.00 42.23  ? 12  PRO A CB  1 
ATOM   98    C CG  . PRO A 1 12  ? -4.294  36.186  -7.584  1.00 41.91  ? 12  PRO A CG  1 
ATOM   99    C CD  . PRO A 1 12  ? -3.505  35.298  -6.652  1.00 39.56  ? 12  PRO A CD  1 
ATOM   100   N N   . GLN A 1 13  ? -5.874  32.251  -7.025  1.00 38.57  ? 13  GLN A N   1 
ATOM   101   C CA  . GLN A 1 13  ? -6.525  30.962  -7.183  1.00 44.24  ? 13  GLN A CA  1 
ATOM   102   C C   . GLN A 1 13  ? -7.026  30.449  -5.840  1.00 50.47  ? 13  GLN A C   1 
ATOM   103   O O   . GLN A 1 13  ? -8.159  29.974  -5.734  1.00 50.43  ? 13  GLN A O   1 
ATOM   104   C CB  . GLN A 1 13  ? -5.599  29.854  -7.656  1.00 49.41  ? 13  GLN A CB  1 
ATOM   105   C CG  . GLN A 1 13  ? -5.220  29.961  -9.122  1.00 57.66  ? 13  GLN A CG  1 
ATOM   106   C CD  . GLN A 1 13  ? -4.292  28.839  -9.510  1.00 59.84  ? 13  GLN A CD  1 
ATOM   107   O OE1 . GLN A 1 13  ? -4.083  27.884  -8.749  1.00 57.83  ? 13  GLN A OE1 1 
ATOM   108   N NE2 . GLN A 1 13  ? -3.731  28.962  -10.699 1.00 60.69  ? 13  GLN A NE2 1 
ATOM   109   N N   . TRP A 1 14  ? -6.152  30.526  -4.829  1.00 45.89  ? 14  TRP A N   1 
ATOM   110   C CA  . TRP A 1 14  ? -6.510  30.110  -3.488  1.00 41.76  ? 14  TRP A CA  1 
ATOM   111   C C   . TRP A 1 14  ? -7.724  30.897  -3.001  1.00 41.35  ? 14  TRP A C   1 
ATOM   112   O O   . TRP A 1 14  ? -8.663  30.306  -2.476  1.00 42.88  ? 14  TRP A O   1 
ATOM   113   C CB  . TRP A 1 14  ? -5.308  30.274  -2.555  1.00 38.45  ? 14  TRP A CB  1 
ATOM   114   C CG  . TRP A 1 14  ? -4.209  29.279  -2.801  1.00 40.85  ? 14  TRP A CG  1 
ATOM   115   C CD1 . TRP A 1 14  ? -4.329  28.027  -3.319  1.00 42.43  ? 14  TRP A CD1 1 
ATOM   116   C CD2 . TRP A 1 14  ? -2.804  29.466  -2.522  1.00 44.01  ? 14  TRP A CD2 1 
ATOM   117   N NE1 . TRP A 1 14  ? -3.101  27.425  -3.389  1.00 43.35  ? 14  TRP A NE1 1 
ATOM   118   C CE2 . TRP A 1 14  ? -2.152  28.271  -2.894  1.00 41.37  ? 14  TRP A CE2 1 
ATOM   119   C CE3 . TRP A 1 14  ? -2.042  30.520  -1.995  1.00 44.99  ? 14  TRP A CE3 1 
ATOM   120   C CZ2 . TRP A 1 14  ? -0.782  28.100  -2.756  1.00 40.52  ? 14  TRP A CZ2 1 
ATOM   121   C CZ3 . TRP A 1 14  ? -0.685  30.347  -1.852  1.00 43.07  ? 14  TRP A CZ3 1 
ATOM   122   C CH2 . TRP A 1 14  ? -0.069  29.149  -2.221  1.00 42.29  ? 14  TRP A CH2 1 
ATOM   123   N N   . ARG A 1 15  ? -7.695  32.222  -3.187  1.00 39.23  ? 15  ARG A N   1 
ATOM   124   C CA  . ARG A 1 15  ? -8.823  33.065  -2.839  1.00 43.49  ? 15  ARG A CA  1 
ATOM   125   C C   . ARG A 1 15  ? -10.116 32.498  -3.427  1.00 41.77  ? 15  ARG A C   1 
ATOM   126   O O   . ARG A 1 15  ? -11.097 32.276  -2.704  1.00 39.87  ? 15  ARG A O   1 
ATOM   127   C CB  . ARG A 1 15  ? -8.533  34.487  -3.315  1.00 46.46  ? 15  ARG A CB  1 
ATOM   128   C CG  . ARG A 1 15  ? -9.715  35.411  -3.102  1.00 50.16  ? 15  ARG A CG  1 
ATOM   129   C CD  . ARG A 1 15  ? -9.316  36.791  -3.526  1.00 58.73  ? 15  ARG A CD  1 
ATOM   130   N NE  . ARG A 1 15  ? -10.495 37.654  -3.655  1.00 68.98  ? 15  ARG A NE  1 
ATOM   131   C CZ  . ARG A 1 15  ? -10.724 38.530  -4.634  1.00 76.05  ? 15  ARG A CZ  1 
ATOM   132   N NH1 . ARG A 1 15  ? -9.879  38.660  -5.647  1.00 83.41  ? 15  ARG A NH1 1 
ATOM   133   N NH2 . ARG A 1 15  ? -11.810 39.281  -4.593  1.00 70.93  ? 15  ARG A NH2 1 
ATOM   134   N N   . ALA A 1 16  ? -10.101 32.234  -4.739  1.00 38.99  ? 16  ALA A N   1 
ATOM   135   C CA  . ALA A 1 16  ? -11.289 31.742  -5.439  1.00 40.01  ? 16  ALA A CA  1 
ATOM   136   C C   . ALA A 1 16  ? -11.710 30.356  -4.944  1.00 35.72  ? 16  ALA A C   1 
ATOM   137   O O   . ALA A 1 16  ? -12.884 30.061  -4.857  1.00 39.44  ? 16  ALA A O   1 
ATOM   138   C CB  . ALA A 1 16  ? -11.063 31.729  -6.947  1.00 40.44  ? 16  ALA A CB  1 
ATOM   139   N N   . GLU A 1 17  ? -10.748 29.497  -4.641  1.00 38.00  ? 17  GLU A N   1 
ATOM   140   C CA  . GLU A 1 17  ? -11.013 28.195  -4.069  1.00 38.36  ? 17  GLU A CA  1 
ATOM   141   C C   . GLU A 1 17  ? -11.656 28.342  -2.692  1.00 40.01  ? 17  GLU A C   1 
ATOM   142   O O   . GLU A 1 17  ? -12.522 27.560  -2.319  1.00 39.85  ? 17  GLU A O   1 
ATOM   143   C CB  . GLU A 1 17  ? -9.655  27.519  -3.910  1.00 48.51  ? 17  GLU A CB  1 
ATOM   144   C CG  . GLU A 1 17  ? -9.515  26.163  -4.594  1.00 58.04  ? 17  GLU A CG  1 
ATOM   145   C CD  . GLU A 1 17  ? -8.046  25.784  -4.699  1.00 66.14  ? 17  GLU A CD  1 
ATOM   146   O OE1 . GLU A 1 17  ? -7.521  25.012  -3.853  1.00 69.61  ? 17  GLU A OE1 1 
ATOM   147   O OE2 . GLU A 1 17  ? -7.433  26.297  -5.652  1.00 60.21  ? 17  GLU A OE2 1 
ATOM   148   N N   . VAL A 1 18  ? -11.195 29.323  -1.905  1.00 41.41  ? 18  VAL A N   1 
ATOM   149   C CA  . VAL A 1 18  ? -11.680 29.495  -0.539  1.00 38.57  ? 18  VAL A CA  1 
ATOM   150   C C   . VAL A 1 18  ? -13.130 30.010  -0.582  1.00 42.75  ? 18  VAL A C   1 
ATOM   151   O O   . VAL A 1 18  ? -13.976 29.442  0.112   1.00 41.27  ? 18  VAL A O   1 
ATOM   152   C CB  . VAL A 1 18  ? -10.711 30.383  0.284   1.00 34.78  ? 18  VAL A CB  1 
ATOM   153   C CG1 . VAL A 1 18  ? -11.297 30.918  1.586   1.00 31.69  ? 18  VAL A CG1 1 
ATOM   154   C CG2 . VAL A 1 18  ? -9.408  29.659  0.585   1.00 36.58  ? 18  VAL A CG2 1 
ATOM   155   N N   . ALA A 1 19  ? -13.424 31.037  -1.419  1.00 43.61  ? 19  ALA A N   1 
ATOM   156   C CA  . ALA A 1 19  ? -14.783 31.562  -1.600  1.00 42.61  ? 19  ALA A CA  1 
ATOM   157   C C   . ALA A 1 19  ? -15.772 30.458  -1.986  1.00 38.95  ? 19  ALA A C   1 
ATOM   158   O O   . ALA A 1 19  ? -16.898 30.459  -1.505  1.00 39.58  ? 19  ALA A O   1 
ATOM   159   C CB  . ALA A 1 19  ? -14.813 32.670  -2.639  1.00 40.19  ? 19  ALA A CB  1 
ATOM   160   N N   . GLU A 1 20  ? -15.347 29.537  -2.861  1.00 42.78  ? 20  GLU A N   1 
ATOM   161   C CA  . GLU A 1 20  ? -16.127 28.371  -3.273  1.00 49.73  ? 20  GLU A CA  1 
ATOM   162   C C   . GLU A 1 20  ? -16.328 27.432  -2.081  1.00 47.16  ? 20  GLU A C   1 
ATOM   163   O O   . GLU A 1 20  ? -17.424 26.933  -1.854  1.00 47.14  ? 20  GLU A O   1 
ATOM   164   C CB  . GLU A 1 20  ? -15.472 27.668  -4.474  1.00 52.90  ? 20  GLU A CB  1 
ATOM   165   C CG  . GLU A 1 20  ? -16.266 26.505  -5.080  1.00 62.97  ? 20  GLU A CG  1 
ATOM   166   C CD  . GLU A 1 20  ? -17.613 26.810  -5.759  1.00 72.07  ? 20  GLU A CD  1 
ATOM   167   O OE1 . GLU A 1 20  ? -18.037 27.996  -5.868  1.00 70.02  ? 20  GLU A OE1 1 
ATOM   168   O OE2 . GLU A 1 20  ? -18.279 25.827  -6.183  1.00 70.21  ? 20  GLU A OE2 1 
ATOM   169   N N   . ILE A 1 21  ? -15.286 27.221  -1.279  1.00 44.39  ? 21  ILE A N   1 
ATOM   170   C CA  . ILE A 1 21  ? -15.421 26.336  -0.141  1.00 42.97  ? 21  ILE A CA  1 
ATOM   171   C C   . ILE A 1 21  ? -16.372 26.959  0.875   1.00 42.12  ? 21  ILE A C   1 
ATOM   172   O O   . ILE A 1 21  ? -17.143 26.238  1.499   1.00 42.11  ? 21  ILE A O   1 
ATOM   173   C CB  . ILE A 1 21  ? -14.039 25.985  0.439   1.00 45.68  ? 21  ILE A CB  1 
ATOM   174   C CG1 . ILE A 1 21  ? -13.303 25.050  -0.482  1.00 45.83  ? 21  ILE A CG1 1 
ATOM   175   C CG2 . ILE A 1 21  ? -14.132 25.393  1.847   1.00 50.10  ? 21  ILE A CG2 1 
ATOM   176   C CD1 . ILE A 1 21  ? -11.809 25.029  -0.231  1.00 50.38  ? 21  ILE A CD1 1 
ATOM   177   N N   . ARG A 1 22  ? -16.316 28.284  1.061   1.00 42.65  ? 22  ARG A N   1 
ATOM   178   C CA  . ARG A 1 22  ? -17.171 28.937  2.054   1.00 45.68  ? 22  ARG A CA  1 
ATOM   179   C C   . ARG A 1 22  ? -18.650 28.926  1.638   1.00 49.70  ? 22  ARG A C   1 
ATOM   180   O O   . ARG A 1 22  ? -19.517 28.738  2.485   1.00 55.81  ? 22  ARG A O   1 
ATOM   181   C CB  . ARG A 1 22  ? -16.710 30.367  2.369   1.00 46.82  ? 22  ARG A CB  1 
ATOM   182   C CG  . ARG A 1 22  ? -15.445 30.423  3.223   1.00 47.78  ? 22  ARG A CG  1 
ATOM   183   C CD  . ARG A 1 22  ? -14.939 31.845  3.475   1.00 43.99  ? 22  ARG A CD  1 
ATOM   184   N NE  . ARG A 1 22  ? -15.782 32.570  4.427   1.00 42.80  ? 22  ARG A NE  1 
ATOM   185   C CZ  . ARG A 1 22  ? -15.868 33.891  4.506   1.00 48.47  ? 22  ARG A CZ  1 
ATOM   186   N NH1 . ARG A 1 22  ? -15.190 34.667  3.667   1.00 48.41  ? 22  ARG A NH1 1 
ATOM   187   N NH2 . ARG A 1 22  ? -16.653 34.439  5.418   1.00 50.71  ? 22  ARG A NH2 1 
ATOM   188   N N   . LYS A 1 23  ? -18.927 29.101  0.337   1.00 48.73  ? 23  LYS A N   1 
ATOM   189   C CA  . LYS A 1 23  ? -20.278 29.164  -0.198  1.00 50.50  ? 23  LYS A CA  1 
ATOM   190   C C   . LYS A 1 23  ? -20.920 27.767  -0.301  1.00 52.72  ? 23  LYS A C   1 
ATOM   191   O O   . LYS A 1 23  ? -22.099 27.604  0.013   1.00 44.66  ? 23  LYS A O   1 
ATOM   192   C CB  . LYS A 1 23  ? -20.141 29.920  -1.526  1.00 56.70  ? 23  LYS A CB  1 
ATOM   193   C CG  . LYS A 1 23  ? -21.386 30.052  -2.398  1.00 69.64  ? 23  LYS A CG  1 
ATOM   194   C CD  . LYS A 1 23  ? -21.099 29.995  -3.900  1.00 74.81  ? 23  LYS A CD  1 
ATOM   195   C CE  . LYS A 1 23  ? -22.321 30.283  -4.728  1.00 85.34  ? 23  LYS A CE  1 
ATOM   196   N NZ  . LYS A 1 23  ? -22.233 29.788  -6.104  1.00 83.95  ? 23  LYS A NZ  1 
ATOM   197   N N   . LYS A 1 24  ? -20.155 26.746  -0.726  1.00 52.10  ? 24  LYS A N   1 
ATOM   198   C CA  . LYS A 1 24  ? -20.714 25.434  -1.045  1.00 52.87  ? 24  LYS A CA  1 
ATOM   199   C C   . LYS A 1 24  ? -20.727 24.482  0.154   1.00 52.62  ? 24  LYS A C   1 
ATOM   200   O O   . LYS A 1 24  ? -21.588 23.610  0.228   1.00 50.33  ? 24  LYS A O   1 
ATOM   201   C CB  . LYS A 1 24  ? -19.916 24.809  -2.196  1.00 56.75  ? 24  LYS A CB  1 
ATOM   202   C CG  . LYS A 1 24  ? -20.472 23.516  -2.773  1.00 61.52  ? 24  LYS A CG  1 
ATOM   203   C CD  . LYS A 1 24  ? -20.123 23.229  -4.236  1.00 67.62  ? 24  LYS A CD  1 
ATOM   204   C CE  . LYS A 1 24  ? -18.858 22.464  -4.516  1.00 68.66  ? 24  LYS A CE  1 
ATOM   205   N NZ  . LYS A 1 24  ? -17.664 23.312  -4.435  1.00 70.75  ? 24  LYS A NZ  1 
ATOM   206   N N   . TYR A 1 25  ? -19.752 24.622  1.066   1.00 52.99  ? 25  TYR A N   1 
ATOM   207   C CA  . TYR A 1 25  ? -19.521 23.653  2.130   1.00 48.81  ? 25  TYR A CA  1 
ATOM   208   C C   . TYR A 1 25  ? -19.428 24.310  3.506   1.00 43.89  ? 25  TYR A C   1 
ATOM   209   O O   . TYR A 1 25  ? -19.133 23.609  4.465   1.00 42.75  ? 25  TYR A O   1 
ATOM   210   C CB  . TYR A 1 25  ? -18.202 22.900  1.933   1.00 50.05  ? 25  TYR A CB  1 
ATOM   211   C CG  . TYR A 1 25  ? -18.057 22.076  0.660   1.00 52.76  ? 25  TYR A CG  1 
ATOM   212   C CD1 . TYR A 1 25  ? -19.052 21.201  0.239   1.00 55.84  ? 25  TYR A CD1 1 
ATOM   213   C CD2 . TYR A 1 25  ? -16.906 22.171  -0.122  1.00 53.79  ? 25  TYR A CD2 1 
ATOM   214   C CE1 . TYR A 1 25  ? -18.895 20.437  -0.910  1.00 60.83  ? 25  TYR A CE1 1 
ATOM   215   C CE2 . TYR A 1 25  ? -16.741 21.422  -1.276  1.00 51.03  ? 25  TYR A CE2 1 
ATOM   216   C CZ  . TYR A 1 25  ? -17.738 20.550  -1.669  1.00 57.77  ? 25  TYR A CZ  1 
ATOM   217   O OH  . TYR A 1 25  ? -17.560 19.816  -2.804  1.00 67.30  ? 25  TYR A OH  1 
ATOM   218   N N   . GLY A 1 26  ? -19.695 25.626  3.607   1.00 42.96  ? 26  GLY A N   1 
ATOM   219   C CA  . GLY A 1 26  ? -19.717 26.328  4.888   1.00 41.95  ? 26  GLY A CA  1 
ATOM   220   C C   . GLY A 1 26  ? -20.596 25.635  5.937   1.00 43.63  ? 26  GLY A C   1 
ATOM   221   O O   . GLY A 1 26  ? -20.306 25.645  7.130   1.00 42.25  ? 26  GLY A O   1 
ATOM   222   N N   . ASN A 1 27  ? -21.692 25.016  5.499   1.00 48.84  ? 27  ASN A N   1 
ATOM   223   C CA  . ASN A 1 27  ? -22.637 24.422  6.430   1.00 50.07  ? 27  ASN A CA  1 
ATOM   224   C C   . ASN A 1 27  ? -22.259 22.974  6.732   1.00 49.71  ? 27  ASN A C   1 
ATOM   225   O O   . ASN A 1 27  ? -23.025 22.279  7.382   1.00 47.51  ? 27  ASN A O   1 
ATOM   226   C CB  . ASN A 1 27  ? -24.086 24.584  5.972   1.00 49.19  ? 27  ASN A CB  1 
ATOM   227   C CG  . ASN A 1 27  ? -24.355 24.174  4.538   1.00 48.24  ? 27  ASN A CG  1 
ATOM   228   O OD1 . ASN A 1 27  ? -23.612 23.399  3.926   1.00 42.93  ? 27  ASN A OD1 1 
ATOM   229   N ND2 . ASN A 1 27  ? -25.449 24.677  3.990   1.00 50.50  ? 27  ASN A ND2 1 
ATOM   230   N N   . ARG A 1 28  ? -21.080 22.522  6.290   1.00 50.32  ? 28  ARG A N   1 
ATOM   231   C CA  . ARG A 1 28  ? -20.673 21.154  6.568   1.00 53.90  ? 28  ARG A CA  1 
ATOM   232   C C   . ARG A 1 28  ? -20.180 21.054  8.015   1.00 52.53  ? 28  ARG A C   1 
ATOM   233   O O   . ARG A 1 28  ? -19.327 21.819  8.453   1.00 51.16  ? 28  ARG A O   1 
ATOM   234   C CB  . ARG A 1 28  ? -19.660 20.702  5.509   1.00 58.01  ? 28  ARG A CB  1 
ATOM   235   C CG  . ARG A 1 28  ? -20.207 20.481  4.101   1.00 61.64  ? 28  ARG A CG  1 
ATOM   236   C CD  . ARG A 1 28  ? -21.346 19.462  4.089   1.00 64.08  ? 28  ARG A CD  1 
ATOM   237   N NE  . ARG A 1 28  ? -21.385 18.548  2.941   1.00 62.27  ? 28  ARG A NE  1 
ATOM   238   C CZ  . ARG A 1 28  ? -21.847 18.842  1.734   1.00 60.85  ? 28  ARG A CZ  1 
ATOM   239   N NH1 . ARG A 1 28  ? -22.287 20.062  1.474   1.00 60.93  ? 28  ARG A NH1 1 
ATOM   240   N NH2 . ARG A 1 28  ? -21.852 17.917  0.787   1.00 60.61  ? 28  ARG A NH2 1 
ATOM   241   N N   . LYS A 1 29  ? -20.746 20.104  8.762   1.00 51.66  ? 29  LYS A N   1 
ATOM   242   C CA  . LYS A 1 29  ? -20.409 19.894  10.161  1.00 49.59  ? 29  LYS A CA  1 
ATOM   243   C C   . LYS A 1 29  ? -19.108 19.098  10.271  1.00 48.01  ? 29  LYS A C   1 
ATOM   244   O O   . LYS A 1 29  ? -18.947 18.099  9.584   1.00 51.15  ? 29  LYS A O   1 
ATOM   245   C CB  . LYS A 1 29  ? -21.557 19.141  10.843  1.00 49.59  ? 29  LYS A CB  1 
ATOM   246   C CG  . LYS A 1 29  ? -21.163 18.342  12.072  1.00 53.51  ? 29  LYS A CG  1 
ATOM   247   C CD  . LYS A 1 29  ? -22.308 17.778  12.899  1.00 53.90  ? 29  LYS A CD  1 
ATOM   248   C CE  . LYS A 1 29  ? -21.774 16.974  14.040  1.00 51.89  ? 29  LYS A CE  1 
ATOM   249   N NZ  . LYS A 1 29  ? -22.718 16.999  15.149  1.00 50.09  ? 29  LYS A NZ  1 
ATOM   250   N N   . THR A 1 30  ? -18.210 19.527  11.169  1.00 47.60  ? 30  THR A N   1 
ATOM   251   C CA  . THR A 1 30  ? -16.940 18.846  11.412  1.00 48.60  ? 30  THR A CA  1 
ATOM   252   C C   . THR A 1 30  ? -16.965 18.160  12.782  1.00 42.48  ? 30  THR A C   1 
ATOM   253   O O   . THR A 1 30  ? -16.327 17.138  12.985  1.00 40.36  ? 30  THR A O   1 
ATOM   254   C CB  . THR A 1 30  ? -15.767 19.832  11.300  1.00 45.34  ? 30  THR A CB  1 
ATOM   255   O OG1 . THR A 1 30  ? -15.931 20.930  12.192  1.00 42.71  ? 30  THR A OG1 1 
ATOM   256   C CG2 . THR A 1 30  ? -15.673 20.467  9.929   1.00 49.06  ? 30  THR A CG2 1 
ATOM   257   N N   . MET A 1 31  ? -17.692 18.724  13.740  1.00 39.67  ? 31  MET A N   1 
ATOM   258   C CA  . MET A 1 31  ? -17.727 18.157  15.072  1.00 36.84  ? 31  MET A CA  1 
ATOM   259   C C   . MET A 1 31  ? -18.755 18.930  15.887  1.00 37.31  ? 31  MET A C   1 
ATOM   260   O O   . MET A 1 31  ? -19.287 19.936  15.414  1.00 38.96  ? 31  MET A O   1 
ATOM   261   C CB  . MET A 1 31  ? -16.351 18.240  15.744  1.00 38.19  ? 31  MET A CB  1 
ATOM   262   C CG  . MET A 1 31  ? -15.768 19.655  15.842  1.00 40.75  ? 31  MET A CG  1 
ATOM   263   S SD  . MET A 1 31  ? -14.038 19.720  16.365  1.00 45.21  ? 31  MET A SD  1 
ATOM   264   C CE  . MET A 1 31  ? -14.225 19.173  18.074  1.00 41.27  ? 31  MET A CE  1 
ATOM   265   N N   . ASP A 1 32  ? -18.995 18.434  17.108  1.00 38.37  ? 32  ASP A N   1 
ATOM   266   C CA  . ASP A 1 32  ? -19.836 19.078  18.094  1.00 36.03  ? 32  ASP A CA  1 
ATOM   267   C C   . ASP A 1 32  ? -18.993 20.071  18.877  1.00 36.19  ? 32  ASP A C   1 
ATOM   268   O O   . ASP A 1 32  ? -17.894 19.734  19.312  1.00 41.04  ? 32  ASP A O   1 
ATOM   269   C CB  . ASP A 1 32  ? -20.467 18.051  19.021  1.00 38.15  ? 32  ASP A CB  1 
ATOM   270   C CG  . ASP A 1 32  ? -21.664 17.296  18.456  1.00 42.16  ? 32  ASP A CG  1 
ATOM   271   O OD1 . ASP A 1 32  ? -22.224 17.749  17.448  1.00 46.59  ? 32  ASP A OD1 1 
ATOM   272   O OD2 . ASP A 1 32  ? -22.035 16.255  19.022  1.00 49.00  ? 32  ASP A OD2 1 
ATOM   273   N N   . CYS A 1 33  ? -19.509 21.294  19.016  1.00 35.40  ? 33  CYS A N   1 
ATOM   274   C CA  . CYS A 1 33  ? -19.013 22.241  19.994  1.00 36.73  ? 33  CYS A CA  1 
ATOM   275   C C   . CYS A 1 33  ? -19.759 21.947  21.299  1.00 38.70  ? 33  CYS A C   1 
ATOM   276   O O   . CYS A 1 33  ? -20.976 21.790  21.270  1.00 38.62  ? 33  CYS A O   1 
ATOM   277   C CB  . CYS A 1 33  ? -19.096 23.670  19.454  1.00 35.84  ? 33  CYS A CB  1 
ATOM   278   S SG  . CYS A 1 33  ? -18.567 24.955  20.632  1.00 41.88  ? 33  CYS A SG  1 
ATOM   279   N N   . THR A 1 34  ? -19.005 21.837  22.412  1.00 43.99  ? 34  THR A N   1 
ATOM   280   C CA  . THR A 1 34  ? -19.486 21.447  23.734  1.00 40.93  ? 34  THR A CA  1 
ATOM   281   C C   . THR A 1 34  ? -19.135 22.519  24.759  1.00 41.14  ? 34  THR A C   1 
ATOM   282   O O   . THR A 1 34  ? -18.393 23.457  24.470  1.00 42.62  ? 34  THR A O   1 
ATOM   283   C CB  . THR A 1 34  ? -18.843 20.140  24.189  1.00 44.19  ? 34  THR A CB  1 
ATOM   284   O OG1 . THR A 1 34  ? -17.493 20.494  24.468  1.00 42.17  ? 34  THR A OG1 1 
ATOM   285   C CG2 . THR A 1 34  ? -18.938 19.043  23.148  1.00 49.52  ? 34  THR A CG2 1 
ATOM   286   N N   . ILE A 1 35  ? -19.637 22.324  25.984  1.00 40.27  ? 35  ILE A N   1 
ATOM   287   C CA  . ILE A 1 35  ? -19.411 23.256  27.075  1.00 38.15  ? 35  ILE A CA  1 
ATOM   288   C C   . ILE A 1 35  ? -17.956 23.146  27.508  1.00 39.28  ? 35  ILE A C   1 
ATOM   289   O O   . ILE A 1 35  ? -17.359 24.151  27.883  1.00 33.93  ? 35  ILE A O   1 
ATOM   290   C CB  . ILE A 1 35  ? -20.414 23.001  28.217  1.00 39.99  ? 35  ILE A CB  1 
ATOM   291   C CG1 . ILE A 1 35  ? -21.708 23.767  27.950  1.00 41.73  ? 35  ILE A CG1 1 
ATOM   292   C CG2 . ILE A 1 35  ? -19.832 23.350  29.589  1.00 38.46  ? 35  ILE A CG2 1 
ATOM   293   C CD1 . ILE A 1 35  ? -22.892 23.295  28.764  1.00 47.83  ? 35  ILE A CD1 1 
ATOM   294   N N   . GLY A 1 36  ? -17.424 21.914  27.433  1.00 39.83  ? 36  GLY A N   1 
ATOM   295   C CA  . GLY A 1 36  ? -16.020 21.613  27.682  1.00 40.90  ? 36  GLY A CA  1 
ATOM   296   C C   . GLY A 1 36  ? -15.060 22.475  26.855  1.00 38.99  ? 36  GLY A C   1 
ATOM   297   O O   . GLY A 1 36  ? -14.136 23.043  27.405  1.00 36.52  ? 36  GLY A O   1 
ATOM   298   N N   . HIS A 1 37  ? -15.295 22.591  25.543  1.00 38.61  ? 37  HIS A N   1 
ATOM   299   C CA  . HIS A 1 37  ? -14.524 23.472  24.680  1.00 40.45  ? 37  HIS A CA  1 
ATOM   300   C C   . HIS A 1 37  ? -14.433 24.918  25.210  1.00 41.24  ? 37  HIS A C   1 
ATOM   301   O O   . HIS A 1 37  ? -13.363 25.521  25.141  1.00 44.15  ? 37  HIS A O   1 
ATOM   302   C CB  . HIS A 1 37  ? -15.086 23.381  23.260  1.00 41.60  ? 37  HIS A CB  1 
ATOM   303   C CG  . HIS A 1 37  ? -14.905 22.055  22.610  1.00 42.11  ? 37  HIS A CG  1 
ATOM   304   N ND1 . HIS A 1 37  ? -13.699 21.376  22.596  1.00 39.81  ? 37  HIS A ND1 1 
ATOM   305   C CD2 . HIS A 1 37  ? -15.775 21.314  21.906  1.00 40.26  ? 37  HIS A CD2 1 
ATOM   306   C CE1 . HIS A 1 37  ? -13.851 20.246  21.915  1.00 41.74  ? 37  HIS A CE1 1 
ATOM   307   N NE2 . HIS A 1 37  ? -15.101 20.197  21.485  1.00 46.19  ? 37  HIS A NE2 1 
ATOM   308   N N   . ALA A 1 38  ? -15.524 25.491  25.747  1.00 40.32  ? 38  ALA A N   1 
ATOM   309   C CA  . ALA A 1 38  ? -15.525 26.868  26.240  1.00 39.25  ? 38  ALA A CA  1 
ATOM   310   C C   . ALA A 1 38  ? -14.690 27.045  27.503  1.00 38.92  ? 38  ALA A C   1 
ATOM   311   O O   . ALA A 1 38  ? -14.005 28.059  27.617  1.00 39.55  ? 38  ALA A O   1 
ATOM   312   C CB  . ALA A 1 38  ? -16.926 27.342  26.515  1.00 40.53  ? 38  ALA A CB  1 
ATOM   313   N N   . TYR A 1 39  ? -14.806 26.087  28.442  1.00 37.46  ? 39  TYR A N   1 
ATOM   314   C CA  . TYR A 1 39  ? -14.078 26.073  29.707  1.00 37.56  ? 39  TYR A CA  1 
ATOM   315   C C   . TYR A 1 39  ? -12.724 25.338  29.586  1.00 37.10  ? 39  TYR A C   1 
ATOM   316   O O   . TYR A 1 39  ? -11.924 25.340  30.517  1.00 36.86  ? 39  TYR A O   1 
ATOM   317   C CB  . TYR A 1 39  ? -14.965 25.442  30.798  1.00 37.11  ? 39  TYR A CB  1 
ATOM   318   C CG  . TYR A 1 39  ? -16.153 26.275  31.263  1.00 36.88  ? 39  TYR A CG  1 
ATOM   319   C CD1 . TYR A 1 39  ? -17.373 26.239  30.599  1.00 36.21  ? 39  TYR A CD1 1 
ATOM   320   C CD2 . TYR A 1 39  ? -16.062 27.092  32.384  1.00 39.12  ? 39  TYR A CD2 1 
ATOM   321   C CE1 . TYR A 1 39  ? -18.445 27.010  31.023  1.00 36.26  ? 39  TYR A CE1 1 
ATOM   322   C CE2 . TYR A 1 39  ? -17.128 27.867  32.820  1.00 38.22  ? 39  TYR A CE2 1 
ATOM   323   C CZ  . TYR A 1 39  ? -18.325 27.826  32.134  1.00 37.76  ? 39  TYR A CZ  1 
ATOM   324   O OH  . TYR A 1 39  ? -19.359 28.605  32.550  1.00 36.93  ? 39  TYR A OH  1 
ATOM   325   N N   . GLY A 1 40  ? -12.424 24.721  28.442  1.00 36.73  ? 40  GLY A N   1 
ATOM   326   C CA  . GLY A 1 40  ? -11.207 23.925  28.289  1.00 35.78  ? 40  GLY A CA  1 
ATOM   327   C C   . GLY A 1 40  ? -10.305 24.443  27.170  1.00 31.51  ? 40  GLY A C   1 
ATOM   328   O O   . GLY A 1 40  ? -9.645  23.664  26.490  1.00 28.33  ? 40  GLY A O   1 
ATOM   329   N N   . GLY A 1 41  ? -10.294 25.767  26.992  1.00 31.94  ? 41  GLY A N   1 
ATOM   330   C CA  . GLY A 1 41  ? -9.382  26.426  26.075  1.00 32.47  ? 41  GLY A CA  1 
ATOM   331   C C   . GLY A 1 41  ? -9.523  25.924  24.638  1.00 35.52  ? 41  GLY A C   1 
ATOM   332   O O   . GLY A 1 41  ? -8.538  25.920  23.897  1.00 39.73  ? 41  GLY A O   1 
ATOM   333   N N   . MET A 1 42  ? -10.738 25.523  24.245  1.00 33.26  ? 42  MET A N   1 
ATOM   334   C CA  . MET A 1 42  ? -11.043 25.099  22.882  1.00 35.92  ? 42  MET A CA  1 
ATOM   335   C C   . MET A 1 42  ? -10.291 23.830  22.450  1.00 33.28  ? 42  MET A C   1 
ATOM   336   O O   . MET A 1 42  ? -10.158 23.591  21.256  1.00 35.06  ? 42  MET A O   1 
ATOM   337   C CB  . MET A 1 42  ? -10.713 26.192  21.846  1.00 37.85  ? 42  MET A CB  1 
ATOM   338   C CG  . MET A 1 42  ? -11.271 27.579  22.137  1.00 36.77  ? 42  MET A CG  1 
ATOM   339   S SD  . MET A 1 42  ? -11.153 28.627  20.669  1.00 39.29  ? 42  MET A SD  1 
ATOM   340   C CE  . MET A 1 42  ? -11.585 30.202  21.418  1.00 39.87  ? 42  MET A CE  1 
ATOM   341   N N   . ARG A 1 43  ? -9.813  22.994  23.381  1.00 36.16  ? 43  ARG A N   1 
ATOM   342   C CA  . ARG A 1 43  ? -9.006  21.837  23.011  1.00 37.32  ? 43  ARG A CA  1 
ATOM   343   C C   . ARG A 1 43  ? -9.768  20.971  22.019  1.00 35.58  ? 43  ARG A C   1 
ATOM   344   O O   . ARG A 1 43  ? -10.890 20.554  22.295  1.00 29.90  ? 43  ARG A O   1 
ATOM   345   C CB  . ARG A 1 43  ? -8.667  20.933  24.196  1.00 43.54  ? 43  ARG A CB  1 
ATOM   346   C CG  . ARG A 1 43  ? -7.434  20.075  23.932  1.00 57.18  ? 43  ARG A CG  1 
ATOM   347   C CD  . ARG A 1 43  ? -6.102  20.891  23.874  1.00 66.24  ? 43  ARG A CD  1 
ATOM   348   N NE  . ARG A 1 43  ? -5.831  21.694  25.084  1.00 64.73  ? 43  ARG A NE  1 
ATOM   349   C CZ  . ARG A 1 43  ? -5.928  23.033  25.284  1.00 57.05  ? 43  ARG A CZ  1 
ATOM   350   N NH1 . ARG A 1 43  ? -5.918  23.576  26.498  1.00 48.60  ? 43  ARG A NH1 1 
ATOM   351   N NH2 . ARG A 1 43  ? -6.116  23.860  24.275  1.00 65.07  ? 43  ARG A NH2 1 
ATOM   352   N N   . GLY A 1 44  ? -9.170  20.742  20.843  1.00 37.44  ? 44  GLY A N   1 
ATOM   353   C CA  . GLY A 1 44  ? -9.740  19.826  19.865  1.00 34.65  ? 44  GLY A CA  1 
ATOM   354   C C   . GLY A 1 44  ? -10.755 20.494  18.933  1.00 35.61  ? 44  GLY A C   1 
ATOM   355   O O   . GLY A 1 44  ? -11.113 19.907  17.900  1.00 33.16  ? 44  GLY A O   1 
ATOM   356   N N   . LEU A 1 45  ? -11.147 21.747  19.243  1.00 34.56  ? 45  LEU A N   1 
ATOM   357   C CA  . LEU A 1 45  ? -12.180 22.439  18.483  1.00 34.83  ? 45  LEU A CA  1 
ATOM   358   C C   . LEU A 1 45  ? -11.594 22.943  17.167  1.00 36.30  ? 45  LEU A C   1 
ATOM   359   O O   . LEU A 1 45  ? -10.601 23.640  17.188  1.00 37.96  ? 45  LEU A O   1 
ATOM   360   C CB  . LEU A 1 45  ? -12.765 23.576  19.320  1.00 33.12  ? 45  LEU A CB  1 
ATOM   361   C CG  . LEU A 1 45  ? -14.097 24.164  18.840  1.00 32.50  ? 45  LEU A CG  1 
ATOM   362   C CD1 . LEU A 1 45  ? -15.199 23.132  18.704  1.00 32.72  ? 45  LEU A CD1 1 
ATOM   363   C CD2 . LEU A 1 45  ? -14.562 25.240  19.790  1.00 32.89  ? 45  LEU A CD2 1 
ATOM   364   N N   . LYS A 1 46  ? -12.230 22.596  16.037  1.00 38.37  ? 46  LYS A N   1 
ATOM   365   C CA  . LYS A 1 46  ? -11.709 22.864  14.705  1.00 40.67  ? 46  LYS A CA  1 
ATOM   366   C C   . LYS A 1 46  ? -12.149 24.251  14.254  1.00 37.40  ? 46  LYS A C   1 
ATOM   367   O O   . LYS A 1 46  ? -12.976 24.378  13.365  1.00 33.00  ? 46  LYS A O   1 
ATOM   368   C CB  . LYS A 1 46  ? -12.147 21.786  13.695  1.00 42.26  ? 46  LYS A CB  1 
ATOM   369   C CG  . LYS A 1 46  ? -11.429 20.429  13.859  1.00 44.79  ? 46  LYS A CG  1 
ATOM   370   C CD  . LYS A 1 46  ? -11.880 19.361  12.868  1.00 47.50  ? 46  LYS A CD  1 
ATOM   371   C CE  . LYS A 1 46  ? -10.944 18.197  12.696  1.00 49.33  ? 46  LYS A CE  1 
ATOM   372   N NZ  . LYS A 1 46  ? -11.264 17.079  13.576  1.00 50.37  ? 46  LYS A NZ  1 
ATOM   373   N N   . ALA A 1 47  ? -11.496 25.271  14.812  1.00 38.53  ? 47  ALA A N   1 
ATOM   374   C CA  . ALA A 1 47  ? -11.995 26.634  14.783  1.00 38.04  ? 47  ALA A CA  1 
ATOM   375   C C   . ALA A 1 47  ? -11.148 27.530  13.882  1.00 38.57  ? 47  ALA A C   1 
ATOM   376   O O   . ALA A 1 47  ? -11.477 28.699  13.710  1.00 41.07  ? 47  ALA A O   1 
ATOM   377   C CB  . ALA A 1 47  ? -12.057 27.166  16.202  1.00 35.25  ? 47  ALA A CB  1 
ATOM   378   N N   . LEU A 1 48  ? -10.094 26.983  13.268  1.00 40.71  ? 48  LEU A N   1 
ATOM   379   C CA  . LEU A 1 48  ? -9.072  27.793  12.612  1.00 40.85  ? 48  LEU A CA  1 
ATOM   380   C C   . LEU A 1 48  ? -8.618  27.136  11.318  1.00 41.24  ? 48  LEU A C   1 
ATOM   381   O O   . LEU A 1 48  ? -8.561  25.912  11.219  1.00 40.86  ? 48  LEU A O   1 
ATOM   382   C CB  . LEU A 1 48  ? -7.854  27.958  13.517  1.00 39.83  ? 48  LEU A CB  1 
ATOM   383   C CG  . LEU A 1 48  ? -7.957  29.037  14.587  1.00 40.63  ? 48  LEU A CG  1 
ATOM   384   C CD1 . LEU A 1 48  ? -6.697  28.980  15.411  1.00 42.85  ? 48  LEU A CD1 1 
ATOM   385   C CD2 . LEU A 1 48  ? -8.149  30.398  13.961  1.00 41.16  ? 48  LEU A CD2 1 
ATOM   386   N N   . VAL A 1 49  ? -8.236  27.985  10.361  1.00 43.19  ? 49  VAL A N   1 
ATOM   387   C CA  . VAL A 1 49  ? -7.617  27.533  9.129   1.00 43.93  ? 49  VAL A CA  1 
ATOM   388   C C   . VAL A 1 49  ? -6.134  27.882  9.170   1.00 36.98  ? 49  VAL A C   1 
ATOM   389   O O   . VAL A 1 49  ? -5.771  28.994  9.536   1.00 36.47  ? 49  VAL A O   1 
ATOM   390   C CB  . VAL A 1 49  ? -8.260  28.178  7.893   1.00 52.84  ? 49  VAL A CB  1 
ATOM   391   C CG1 . VAL A 1 49  ? -7.529  27.750  6.622   1.00 52.39  ? 49  VAL A CG1 1 
ATOM   392   C CG2 . VAL A 1 49  ? -9.752  27.877  7.812   1.00 57.30  ? 49  VAL A CG2 1 
ATOM   393   N N   . CYS A 1 50  ? -5.304  26.908  8.790   1.00 36.11  ? 50  CYS A N   1 
ATOM   394   C CA  . CYS A 1 50  ? -3.886  27.106  8.551   1.00 32.70  ? 50  CYS A CA  1 
ATOM   395   C C   . CYS A 1 50  ? -3.420  26.157  7.451   1.00 32.89  ? 50  CYS A C   1 
ATOM   396   O O   . CYS A 1 50  ? -3.658  24.948  7.549   1.00 31.11  ? 50  CYS A O   1 
ATOM   397   C CB  . CYS A 1 50  ? -3.102  26.833  9.815   1.00 31.65  ? 50  CYS A CB  1 
ATOM   398   S SG  . CYS A 1 50  ? -1.329  26.989  9.558   1.00 39.06  ? 50  CYS A SG  1 
ATOM   399   N N   . ASP A 1 51  ? -2.781  26.713  6.407   1.00 31.98  ? 51  ASP A N   1 
ATOM   400   C CA  . ASP A 1 51  ? -2.287  25.896  5.311   1.00 36.44  ? 51  ASP A CA  1 
ATOM   401   C C   . ASP A 1 51  ? -0.765  25.757  5.312   1.00 37.45  ? 51  ASP A C   1 
ATOM   402   O O   . ASP A 1 51  ? -0.246  24.999  4.488   1.00 35.27  ? 51  ASP A O   1 
ATOM   403   C CB  . ASP A 1 51  ? -2.812  26.366  3.965   1.00 39.06  ? 51  ASP A CB  1 
ATOM   404   C CG  . ASP A 1 51  ? -4.296  26.128  3.767   1.00 37.53  ? 51  ASP A CG  1 
ATOM   405   O OD1 . ASP A 1 51  ? -4.725  24.985  4.041   1.00 37.06  ? 51  ASP A OD1 1 
ATOM   406   O OD2 . ASP A 1 51  ? -4.996  27.086  3.372   1.00 36.86  ? 51  ASP A OD2 1 
ATOM   407   N N   . THR A 1 52  ? -0.064  26.431  6.243   1.00 36.01  ? 52  THR A N   1 
ATOM   408   C CA  . THR A 1 52  ? 1.387   26.359  6.307   1.00 33.14  ? 52  THR A CA  1 
ATOM   409   C C   . THR A 1 52  ? 1.842   25.010  6.879   1.00 32.14  ? 52  THR A C   1 
ATOM   410   O O   . THR A 1 52  ? 2.753   24.381  6.353   1.00 31.93  ? 52  THR A O   1 
ATOM   411   C CB  . THR A 1 52  ? 1.951   27.567  7.056   1.00 33.91  ? 52  THR A CB  1 
ATOM   412   O OG1 . THR A 1 52  ? 1.234   27.739  8.277   1.00 36.77  ? 52  THR A OG1 1 
ATOM   413   C CG2 . THR A 1 52  ? 1.850   28.828  6.215   1.00 31.81  ? 52  THR A CG2 1 
ATOM   414   N N   . SER A 1 53  ? 1.178   24.500  7.908   1.00 34.22  ? 53  SER A N   1 
ATOM   415   C CA  . SER A 1 53  ? 1.569   23.206  8.439   1.00 35.55  ? 53  SER A CA  1 
ATOM   416   C C   . SER A 1 53  ? 0.400   22.523  9.145   1.00 36.91  ? 53  SER A C   1 
ATOM   417   O O   . SER A 1 53  ? -0.601  23.158  9.480   1.00 37.96  ? 53  SER A O   1 
ATOM   418   C CB  . SER A 1 53  ? 2.774   23.335  9.354   1.00 39.74  ? 53  SER A CB  1 
ATOM   419   O OG  . SER A 1 53  ? 2.514   24.184  10.468  1.00 38.41  ? 53  SER A OG  1 
ATOM   420   N N   . GLU A 1 54  ? 0.581   21.216  9.380   1.00 41.85  ? 54  GLU A N   1 
ATOM   421   C CA  . GLU A 1 54  ? -0.401  20.360  10.023  1.00 43.06  ? 54  GLU A CA  1 
ATOM   422   C C   . GLU A 1 54  ? 0.304   19.461  11.037  1.00 39.36  ? 54  GLU A C   1 
ATOM   423   O O   . GLU A 1 54  ? 1.241   18.770  10.686  1.00 43.74  ? 54  GLU A O   1 
ATOM   424   C CB  . GLU A 1 54  ? -1.103  19.551  8.931   1.00 42.37  ? 54  GLU A CB  1 
ATOM   425   C CG  . GLU A 1 54  ? -2.384  18.880  9.420   1.00 43.26  ? 54  GLU A CG  1 
ATOM   426   C CD  . GLU A 1 54  ? -3.265  18.277  8.337   1.00 44.15  ? 54  GLU A CD  1 
ATOM   427   O OE1 . GLU A 1 54  ? -4.374  17.796  8.684   1.00 50.50  ? 54  GLU A OE1 1 
ATOM   428   O OE2 . GLU A 1 54  ? -2.859  18.308  7.160   1.00 42.53  ? 54  GLU A OE2 1 
ATOM   429   N N   . VAL A 1 55  ? -0.169  19.461  12.285  1.00 42.61  ? 55  VAL A N   1 
ATOM   430   C CA  . VAL A 1 55  ? 0.327   18.579  13.333  1.00 44.24  ? 55  VAL A CA  1 
ATOM   431   C C   . VAL A 1 55  ? -0.566  17.346  13.422  1.00 49.36  ? 55  VAL A C   1 
ATOM   432   O O   . VAL A 1 55  ? -1.709  17.426  13.880  1.00 48.37  ? 55  VAL A O   1 
ATOM   433   C CB  . VAL A 1 55  ? 0.355   19.284  14.700  1.00 43.93  ? 55  VAL A CB  1 
ATOM   434   C CG1 . VAL A 1 55  ? 0.734   18.320  15.816  1.00 43.69  ? 55  VAL A CG1 1 
ATOM   435   C CG2 . VAL A 1 55  ? 1.269   20.496  14.703  1.00 44.94  ? 55  VAL A CG2 1 
ATOM   436   N N   . PHE A 1 56  ? -0.043  16.215  12.954  1.00 56.82  ? 56  PHE A N   1 
ATOM   437   C CA  . PHE A 1 56  ? -0.710  14.935  13.122  1.00 66.29  ? 56  PHE A CA  1 
ATOM   438   C C   . PHE A 1 56  ? -0.294  14.394  14.491  1.00 76.35  ? 56  PHE A C   1 
ATOM   439   O O   . PHE A 1 56  ? 0.895   14.326  14.792  1.00 90.00  ? 56  PHE A O   1 
ATOM   440   C CB  . PHE A 1 56  ? -0.346  14.011  11.952  1.00 64.32  ? 56  PHE A CB  1 
ATOM   441   C CG  . PHE A 1 56  ? -0.734  14.509  10.563  1.00 61.82  ? 56  PHE A CG  1 
ATOM   442   C CD1 . PHE A 1 56  ? 0.052   15.448  9.895   1.00 61.45  ? 56  PHE A CD1 1 
ATOM   443   C CD2 . PHE A 1 56  ? -1.864  14.009  9.911   1.00 55.69  ? 56  PHE A CD2 1 
ATOM   444   C CE1 . PHE A 1 56  ? -0.287  15.890  8.622   1.00 63.36  ? 56  PHE A CE1 1 
ATOM   445   C CE2 . PHE A 1 56  ? -2.193  14.446  8.636   1.00 58.40  ? 56  PHE A CE2 1 
ATOM   446   C CZ  . PHE A 1 56  ? -1.410  15.392  7.995   1.00 62.15  ? 56  PHE A CZ  1 
ATOM   447   N N   . PRO A 1 57  ? -1.237  14.084  15.410  1.00 82.78  ? 57  PRO A N   1 
ATOM   448   C CA  . PRO A 1 57  ? -0.874  13.396  16.657  1.00 77.31  ? 57  PRO A CA  1 
ATOM   449   C C   . PRO A 1 57  ? 0.053   12.170  16.600  1.00 75.08  ? 57  PRO A C   1 
ATOM   450   O O   . PRO A 1 57  ? 0.864   11.977  17.508  1.00 78.22  ? 57  PRO A O   1 
ATOM   451   C CB  . PRO A 1 57  ? -2.286  13.061  17.197  1.00 78.85  ? 57  PRO A CB  1 
ATOM   452   C CG  . PRO A 1 57  ? -3.150  14.234  16.759  1.00 72.90  ? 57  PRO A CG  1 
ATOM   453   C CD  . PRO A 1 57  ? -2.655  14.506  15.359  1.00 74.93  ? 57  PRO A CD  1 
ATOM   454   N N   . ASP A 1 58  ? -0.041  11.354  15.538  1.00 73.37  ? 58  ASP A N   1 
ATOM   455   C CA  . ASP A 1 58  ? 0.712   10.106  15.442  1.00 79.39  ? 58  ASP A CA  1 
ATOM   456   C C   . ASP A 1 58  ? 1.972   10.233  14.576  1.00 82.06  ? 58  ASP A C   1 
ATOM   457   O O   . ASP A 1 58  ? 2.737   9.276   14.495  1.00 91.31  ? 58  ASP A O   1 
ATOM   458   C CB  . ASP A 1 58  ? -0.138  8.967   14.884  1.00 82.03  ? 58  ASP A CB  1 
ATOM   459   C CG  . ASP A 1 58  ? -1.186  8.344   15.802  1.00 77.73  ? 58  ASP A CG  1 
ATOM   460   O OD1 . ASP A 1 58  ? -1.235  8.678   17.012  1.00 64.44  ? 58  ASP A OD1 1 
ATOM   461   O OD2 . ASP A 1 58  ? -1.963  7.518   15.287  1.00 77.47  ? 58  ASP A OD2 1 
ATOM   462   N N   . GLU A 1 59  ? 2.195   11.382  13.914  1.00 79.72  ? 59  GLU A N   1 
ATOM   463   C CA  . GLU A 1 59  ? 3.346   11.547  13.027  1.00 70.58  ? 59  GLU A CA  1 
ATOM   464   C C   . GLU A 1 59  ? 4.186   12.796  13.341  1.00 58.79  ? 59  GLU A C   1 
ATOM   465   O O   . GLU A 1 59  ? 5.373   12.815  13.050  1.00 54.82  ? 59  GLU A O   1 
ATOM   466   C CB  . GLU A 1 59  ? 2.904   11.607  11.566  1.00 76.90  ? 59  GLU A CB  1 
ATOM   467   C CG  . GLU A 1 59  ? 2.203   10.347  11.060  1.00 79.47  ? 59  GLU A CG  1 
ATOM   468   C CD  . GLU A 1 59  ? 2.132   10.331  9.540   1.00 74.38  ? 59  GLU A CD  1 
ATOM   469   O OE1 . GLU A 1 59  ? 3.228   10.286  8.934   1.00 64.57  ? 59  GLU A OE1 1 
ATOM   470   O OE2 . GLU A 1 59  ? 1.018   10.404  8.965   1.00 66.13  ? 59  GLU A OE2 1 
ATOM   471   N N   . GLY A 1 60  ? 3.579   13.852  13.900  1.00 54.81  ? 60  GLY A N   1 
ATOM   472   C CA  . GLY A 1 60  ? 4.258   15.108  14.189  1.00 50.58  ? 60  GLY A CA  1 
ATOM   473   C C   . GLY A 1 60  ? 3.846   16.188  13.189  1.00 50.34  ? 60  GLY A C   1 
ATOM   474   O O   . GLY A 1 60  ? 2.931   15.977  12.385  1.00 45.05  ? 60  GLY A O   1 
ATOM   475   N N   . VAL A 1 61  ? 4.551   17.329  13.218  1.00 44.37  ? 61  VAL A N   1 
ATOM   476   C CA  . VAL A 1 61  ? 4.261   18.425  12.304  1.00 39.98  ? 61  VAL A CA  1 
ATOM   477   C C   . VAL A 1 61  ? 4.753   18.092  10.890  1.00 38.88  ? 61  VAL A C   1 
ATOM   478   O O   . VAL A 1 61  ? 5.834   17.529  10.707  1.00 38.65  ? 61  VAL A O   1 
ATOM   479   C CB  . VAL A 1 61  ? 4.869   19.750  12.797  1.00 39.90  ? 61  VAL A CB  1 
ATOM   480   C CG1 . VAL A 1 61  ? 6.390   19.742  12.724  1.00 38.05  ? 61  VAL A CG1 1 
ATOM   481   C CG2 . VAL A 1 61  ? 4.308   20.948  12.032  1.00 43.30  ? 61  VAL A CG2 1 
ATOM   482   N N   . LYS A 1 62  ? 3.942   18.475  9.894   1.00 35.84  ? 62  LYS A N   1 
ATOM   483   C CA  . LYS A 1 62  ? 4.292   18.382  8.490   1.00 38.52  ? 62  LYS A CA  1 
ATOM   484   C C   . LYS A 1 62  ? 4.118   19.748  7.847   1.00 36.76  ? 62  LYS A C   1 
ATOM   485   O O   . LYS A 1 62  ? 3.068   20.365  7.961   1.00 34.85  ? 62  LYS A O   1 
ATOM   486   C CB  . LYS A 1 62  ? 3.412   17.376  7.746   1.00 43.82  ? 62  LYS A CB  1 
ATOM   487   C CG  . LYS A 1 62  ? 3.771   15.926  8.038   1.00 47.14  ? 62  LYS A CG  1 
ATOM   488   C CD  . LYS A 1 62  ? 3.064   14.970  7.081   1.00 50.36  ? 62  LYS A CD  1 
ATOM   489   C CE  . LYS A 1 62  ? 3.125   13.560  7.575   1.00 52.19  ? 62  LYS A CE  1 
ATOM   490   N NZ  . LYS A 1 62  ? 2.219   12.670  6.854   1.00 50.22  ? 62  LYS A NZ  1 
ATOM   491   N N   . PHE A 1 63  ? 5.173   20.207  7.173   1.00 40.41  ? 63  PHE A N   1 
ATOM   492   C CA  . PHE A 1 63  ? 5.203   21.537  6.586   1.00 37.85  ? 63  PHE A CA  1 
ATOM   493   C C   . PHE A 1 63  ? 4.787   21.475  5.119   1.00 37.13  ? 63  PHE A C   1 
ATOM   494   O O   . PHE A 1 63  ? 5.581   21.040  4.297   1.00 36.68  ? 63  PHE A O   1 
ATOM   495   C CB  . PHE A 1 63  ? 6.644   22.031  6.712   1.00 36.97  ? 63  PHE A CB  1 
ATOM   496   C CG  . PHE A 1 63  ? 7.217   22.248  8.106   1.00 32.58  ? 63  PHE A CG  1 
ATOM   497   C CD1 . PHE A 1 63  ? 6.544   22.993  9.060   1.00 32.19  ? 63  PHE A CD1 1 
ATOM   498   C CD2 . PHE A 1 63  ? 8.500   21.822  8.411   1.00 32.76  ? 63  PHE A CD2 1 
ATOM   499   C CE1 . PHE A 1 63  ? 7.129   23.252  10.295  1.00 33.12  ? 63  PHE A CE1 1 
ATOM   500   C CE2 . PHE A 1 63  ? 9.066   22.078  9.652   1.00 32.48  ? 63  PHE A CE2 1 
ATOM   501   C CZ  . PHE A 1 63  ? 8.381   22.785  10.591  1.00 29.88  ? 63  PHE A CZ  1 
ATOM   502   N N   . ARG A 1 64  ? 3.564   21.932  4.798   1.00 37.22  ? 64  ARG A N   1 
ATOM   503   C CA  . ARG A 1 64  ? 2.994   21.801  3.468   1.00 35.01  ? 64  ARG A CA  1 
ATOM   504   C C   . ARG A 1 64  ? 3.099   20.342  3.007   1.00 39.63  ? 64  ARG A C   1 
ATOM   505   O O   . ARG A 1 64  ? 3.446   20.066  1.849   1.00 37.33  ? 64  ARG A O   1 
ATOM   506   C CB  . ARG A 1 64  ? 3.661   22.741  2.462   1.00 34.67  ? 64  ARG A CB  1 
ATOM   507   C CG  . ARG A 1 64  ? 3.319   24.210  2.612   1.00 37.03  ? 64  ARG A CG  1 
ATOM   508   C CD  . ARG A 1 64  ? 1.929   24.533  2.082   1.00 36.99  ? 64  ARG A CD  1 
ATOM   509   N NE  . ARG A 1 64  ? 1.684   25.980  2.151   1.00 38.18  ? 64  ARG A NE  1 
ATOM   510   C CZ  . ARG A 1 64  ? 0.644   26.653  1.653   1.00 38.37  ? 64  ARG A CZ  1 
ATOM   511   N NH1 . ARG A 1 64  ? -0.315  26.026  1.007   1.00 33.54  ? 64  ARG A NH1 1 
ATOM   512   N NH2 . ARG A 1 64  ? 0.578   27.971  1.784   1.00 41.88  ? 64  ARG A NH2 1 
ATOM   513   N N   . GLY A 1 65  ? 2.790   19.406  3.916   1.00 40.95  ? 65  GLY A N   1 
ATOM   514   C CA  . GLY A 1 65  ? 2.710   17.999  3.553   1.00 42.93  ? 65  GLY A CA  1 
ATOM   515   C C   . GLY A 1 65  ? 4.046   17.251  3.650   1.00 45.93  ? 65  GLY A C   1 
ATOM   516   O O   . GLY A 1 65  ? 4.034   16.019  3.597   1.00 47.44  ? 65  GLY A O   1 
ATOM   517   N N   . TYR A 1 66  ? 5.183   17.959  3.805   1.00 43.66  ? 66  TYR A N   1 
ATOM   518   C CA  . TYR A 1 66  ? 6.484   17.301  3.948   1.00 44.92  ? 66  TYR A CA  1 
ATOM   519   C C   . TYR A 1 66  ? 6.850   17.060  5.420   1.00 44.47  ? 66  TYR A C   1 
ATOM   520   O O   . TYR A 1 66  ? 6.594   17.897  6.288   1.00 39.81  ? 66  TYR A O   1 
ATOM   521   C CB  . TYR A 1 66  ? 7.579   18.126  3.274   1.00 42.86  ? 66  TYR A CB  1 
ATOM   522   C CG  . TYR A 1 66  ? 7.307   18.336  1.797   1.00 45.11  ? 66  TYR A CG  1 
ATOM   523   C CD1 . TYR A 1 66  ? 7.665   17.380  0.861   1.00 49.94  ? 66  TYR A CD1 1 
ATOM   524   C CD2 . TYR A 1 66  ? 6.656   19.472  1.350   1.00 45.88  ? 66  TYR A CD2 1 
ATOM   525   C CE1 . TYR A 1 66  ? 7.398   17.558  -0.485  1.00 49.96  ? 66  TYR A CE1 1 
ATOM   526   C CE2 . TYR A 1 66  ? 6.362   19.653  0.014   1.00 45.39  ? 66  TYR A CE2 1 
ATOM   527   C CZ  . TYR A 1 66  ? 6.738   18.696  -0.902  1.00 45.64  ? 66  TYR A CZ  1 
ATOM   528   O OH  . TYR A 1 66  ? 6.470   18.904  -2.214  1.00 46.63  ? 66  TYR A OH  1 
ATOM   529   N N   . THR A 1 67  ? 7.468   15.896  5.683   1.00 44.41  ? 67  THR A N   1 
ATOM   530   C CA  . THR A 1 67  ? 7.999   15.565  6.999   1.00 46.65  ? 67  THR A CA  1 
ATOM   531   C C   . THR A 1 67  ? 9.361   16.237  7.164   1.00 42.42  ? 67  THR A C   1 
ATOM   532   O O   . THR A 1 67  ? 10.022  16.537  6.170   1.00 39.95  ? 67  THR A O   1 
ATOM   533   C CB  . THR A 1 67  ? 8.124   14.050  7.195   1.00 50.78  ? 67  THR A CB  1 
ATOM   534   O OG1 . THR A 1 67  ? 9.201   13.616  6.374   1.00 53.64  ? 67  THR A OG1 1 
ATOM   535   C CG2 . THR A 1 67  ? 6.866   13.280  6.836   1.00 52.23  ? 67  THR A CG2 1 
ATOM   536   N N   . ILE A 1 68  ? 9.777   16.429  8.428   1.00 40.30  ? 68  ILE A N   1 
ATOM   537   C CA  . ILE A 1 68  ? 11.075  17.007  8.761   1.00 39.45  ? 68  ILE A CA  1 
ATOM   538   C C   . ILE A 1 68  ? 12.210  16.143  8.188   1.00 40.32  ? 68  ILE A C   1 
ATOM   539   O O   . ILE A 1 68  ? 13.135  16.682  7.585   1.00 36.88  ? 68  ILE A O   1 
ATOM   540   C CB  . ILE A 1 68  ? 11.197  17.244  10.280  1.00 36.55  ? 68  ILE A CB  1 
ATOM   541   C CG1 . ILE A 1 68  ? 10.348  18.445  10.719  1.00 37.46  ? 68  ILE A CG1 1 
ATOM   542   C CG2 . ILE A 1 68  ? 12.662  17.402  10.705  1.00 36.98  ? 68  ILE A CG2 1 
ATOM   543   C CD1 . ILE A 1 68  ? 10.162  18.569  12.223  1.00 38.77  ? 68  ILE A CD1 1 
ATOM   544   N N   . PRO A 1 69  ? 12.211  14.796  8.355   1.00 42.54  ? 69  PRO A N   1 
ATOM   545   C CA  . PRO A 1 69  ? 13.194  13.963  7.658   1.00 42.49  ? 69  PRO A CA  1 
ATOM   546   C C   . PRO A 1 69  ? 13.220  14.205  6.153   1.00 40.13  ? 69  PRO A C   1 
ATOM   547   O O   . PRO A 1 69  ? 14.288  14.325  5.557   1.00 34.11  ? 69  PRO A O   1 
ATOM   548   C CB  . PRO A 1 69  ? 12.769  12.535  8.051   1.00 44.36  ? 69  PRO A CB  1 
ATOM   549   C CG  . PRO A 1 69  ? 12.161  12.715  9.452   1.00 44.55  ? 69  PRO A CG  1 
ATOM   550   C CD  . PRO A 1 69  ? 11.392  14.022  9.315   1.00 42.77  ? 69  PRO A CD  1 
ATOM   551   N N   . GLU A 1 70  ? 12.046  14.342  5.535   1.00 45.02  ? 70  GLU A N   1 
ATOM   552   C CA  . GLU A 1 70  ? 12.006  14.575  4.098   1.00 44.65  ? 70  GLU A CA  1 
ATOM   553   C C   . GLU A 1 70  ? 12.832  15.813  3.763   1.00 43.04  ? 70  GLU A C   1 
ATOM   554   O O   . GLU A 1 70  ? 13.617  15.792  2.827   1.00 45.02  ? 70  GLU A O   1 
ATOM   555   C CB  . GLU A 1 70  ? 10.588  14.730  3.558   1.00 46.61  ? 70  GLU A CB  1 
ATOM   556   C CG  . GLU A 1 70  ? 9.888   13.403  3.265   1.00 52.78  ? 70  GLU A CG  1 
ATOM   557   C CD  . GLU A 1 70  ? 8.436   13.558  2.823   1.00 57.85  ? 70  GLU A CD  1 
ATOM   558   O OE1 . GLU A 1 70  ? 8.145   13.483  1.602   1.00 60.92  ? 70  GLU A OE1 1 
ATOM   559   O OE2 . GLU A 1 70  ? 7.596   13.770  3.719   1.00 56.55  ? 70  GLU A OE2 1 
ATOM   560   N N   . LEU A 1 71  ? 12.661  16.885  4.543   1.00 40.66  ? 71  LEU A N   1 
ATOM   561   C CA  . LEU A 1 71  ? 13.190  18.179  4.151   1.00 40.51  ? 71  LEU A CA  1 
ATOM   562   C C   . LEU A 1 71  ? 14.664  18.322  4.542   1.00 42.28  ? 71  LEU A C   1 
ATOM   563   O O   . LEU A 1 71  ? 15.415  19.059  3.897   1.00 39.45  ? 71  LEU A O   1 
ATOM   564   C CB  . LEU A 1 71  ? 12.322  19.256  4.795   1.00 36.24  ? 71  LEU A CB  1 
ATOM   565   C CG  . LEU A 1 71  ? 10.892  19.351  4.267   1.00 35.35  ? 71  LEU A CG  1 
ATOM   566   C CD1 . LEU A 1 71  ? 10.118  20.289  5.183   1.00 37.44  ? 71  LEU A CD1 1 
ATOM   567   C CD2 . LEU A 1 71  ? 10.768  19.836  2.819   1.00 36.61  ? 71  LEU A CD2 1 
ATOM   568   N N   . ARG A 1 72  ? 15.060  17.622  5.609   1.00 43.82  ? 72  ARG A N   1 
ATOM   569   C CA  . ARG A 1 72  ? 16.382  17.756  6.191   1.00 45.07  ? 72  ARG A CA  1 
ATOM   570   C C   . ARG A 1 72  ? 17.368  16.757  5.580   1.00 44.42  ? 72  ARG A C   1 
ATOM   571   O O   . ARG A 1 72  ? 18.525  17.106  5.356   1.00 40.02  ? 72  ARG A O   1 
ATOM   572   C CB  . ARG A 1 72  ? 16.220  17.552  7.699   1.00 43.30  ? 72  ARG A CB  1 
ATOM   573   C CG  . ARG A 1 72  ? 17.531  17.625  8.464   1.00 42.38  ? 72  ARG A CG  1 
ATOM   574   C CD  . ARG A 1 72  ? 17.311  17.982  9.932   1.00 42.82  ? 72  ARG A CD  1 
ATOM   575   N NE  . ARG A 1 72  ? 18.579  17.937  10.666  1.00 42.45  ? 72  ARG A NE  1 
ATOM   576   C CZ  . ARG A 1 72  ? 19.201  16.836  11.057  1.00 42.37  ? 72  ARG A CZ  1 
ATOM   577   N NH1 . ARG A 1 72  ? 18.557  15.686  11.107  1.00 41.30  ? 72  ARG A NH1 1 
ATOM   578   N NH2 . ARG A 1 72  ? 20.458  16.910  11.445  1.00 44.17  ? 72  ARG A NH2 1 
ATOM   579   N N   . GLU A 1 73  ? 16.910  15.516  5.352   1.00 47.86  ? 73  GLU A N   1 
ATOM   580   C CA  . GLU A 1 73  ? 17.768  14.410  4.930   1.00 52.92  ? 73  GLU A CA  1 
ATOM   581   C C   . GLU A 1 73  ? 17.521  13.998  3.478   1.00 49.34  ? 73  GLU A C   1 
ATOM   582   O O   . GLU A 1 73  ? 18.361  13.303  2.919   1.00 47.53  ? 73  GLU A O   1 
ATOM   583   C CB  . GLU A 1 73  ? 17.565  13.140  5.764   1.00 53.58  ? 73  GLU A CB  1 
ATOM   584   C CG  . GLU A 1 73  ? 17.765  13.375  7.257   1.00 64.56  ? 73  GLU A CG  1 
ATOM   585   C CD  . GLU A 1 73  ? 17.702  12.162  8.163   1.00 72.31  ? 73  GLU A CD  1 
ATOM   586   O OE1 . GLU A 1 73  ? 18.793  11.774  8.637   1.00 74.63  ? 73  GLU A OE1 1 
ATOM   587   O OE2 . GLU A 1 73  ? 16.587  11.649  8.433   1.00 75.19  ? 73  GLU A OE2 1 
ATOM   588   N N   . GLY A 1 74  ? 16.385  14.420  2.894   1.00 49.70  ? 74  GLY A N   1 
ATOM   589   C CA  . GLY A 1 74  ? 15.835  13.864  1.660   1.00 44.44  ? 74  GLY A CA  1 
ATOM   590   C C   . GLY A 1 74  ? 14.692  12.896  1.969   1.00 40.63  ? 74  GLY A C   1 
ATOM   591   O O   . GLY A 1 74  ? 14.533  12.487  3.115   1.00 42.70  ? 74  GLY A O   1 
ATOM   592   N N   . PRO A 1 75  ? 13.880  12.458  0.978   1.00 37.05  ? 75  PRO A N   1 
ATOM   593   C CA  . PRO A 1 75  ? 14.153  12.709  -0.432  1.00 41.00  ? 75  PRO A CA  1 
ATOM   594   C C   . PRO A 1 75  ? 13.601  14.005  -1.010  1.00 41.74  ? 75  PRO A C   1 
ATOM   595   O O   . PRO A 1 75  ? 13.475  14.083  -2.218  1.00 52.77  ? 75  PRO A O   1 
ATOM   596   C CB  . PRO A 1 75  ? 13.474  11.487  -1.066  1.00 38.20  ? 75  PRO A CB  1 
ATOM   597   C CG  . PRO A 1 75  ? 12.209  11.331  -0.259  1.00 38.36  ? 75  PRO A CG  1 
ATOM   598   C CD  . PRO A 1 75  ? 12.655  11.662  1.159   1.00 37.88  ? 75  PRO A CD  1 
ATOM   599   N N   . HIS A 1 76  ? 13.254  14.996  -0.176  1.00 40.68  ? 76  HIS A N   1 
ATOM   600   C CA  . HIS A 1 76  ? 12.890  16.310  -0.688  1.00 42.60  ? 76  HIS A CA  1 
ATOM   601   C C   . HIS A 1 76  ? 13.632  17.403  0.082   1.00 40.47  ? 76  HIS A C   1 
ATOM   602   O O   . HIS A 1 76  ? 13.020  18.254  0.727   1.00 39.36  ? 76  HIS A O   1 
ATOM   603   C CB  . HIS A 1 76  ? 11.372  16.519  -0.638  1.00 48.22  ? 76  HIS A CB  1 
ATOM   604   C CG  . HIS A 1 76  ? 10.568  15.639  -1.540  1.00 49.45  ? 76  HIS A CG  1 
ATOM   605   N ND1 . HIS A 1 76  ? 10.626  15.721  -2.918  1.00 55.78  ? 76  HIS A ND1 1 
ATOM   606   C CD2 . HIS A 1 76  ? 9.694   14.662  -1.248  1.00 48.11  ? 76  HIS A CD2 1 
ATOM   607   C CE1 . HIS A 1 76  ? 9.795   14.823  -3.433  1.00 60.18  ? 76  HIS A CE1 1 
ATOM   608   N NE2 . HIS A 1 76  ? 9.216   14.171  -2.431  1.00 56.42  ? 76  HIS A NE2 1 
ATOM   609   N N   . LYS A 1 77  ? 14.960  17.389  -0.040  1.00 37.15  ? 77  LYS A N   1 
ATOM   610   C CA  . LYS A 1 77  ? 15.832  18.170  0.811   1.00 39.39  ? 77  LYS A CA  1 
ATOM   611   C C   . LYS A 1 77  ? 15.836  19.639  0.401   1.00 37.06  ? 77  LYS A C   1 
ATOM   612   O O   . LYS A 1 77  ? 16.042  19.981  -0.758  1.00 36.14  ? 77  LYS A O   1 
ATOM   613   C CB  . LYS A 1 77  ? 17.251  17.593  0.761   1.00 43.10  ? 77  LYS A CB  1 
ATOM   614   C CG  . LYS A 1 77  ? 18.186  18.136  1.819   1.00 41.12  ? 77  LYS A CG  1 
ATOM   615   C CD  . LYS A 1 77  ? 19.583  17.549  1.777   1.00 43.77  ? 77  LYS A CD  1 
ATOM   616   C CE  . LYS A 1 77  ? 20.545  18.443  2.497   1.00 51.83  ? 77  LYS A CE  1 
ATOM   617   N NZ  . LYS A 1 77  ? 20.239  18.520  3.931   1.00 56.17  ? 77  LYS A NZ  1 
ATOM   618   N N   . LEU A 1 78  ? 15.651  20.515  1.390   1.00 36.72  ? 78  LEU A N   1 
ATOM   619   C CA  . LEU A 1 78  ? 15.731  21.951  1.155   1.00 38.28  ? 78  LEU A CA  1 
ATOM   620   C C   . LEU A 1 78  ? 17.185  22.387  0.939   1.00 35.26  ? 78  LEU A C   1 
ATOM   621   O O   . LEU A 1 78  ? 18.112  21.828  1.520   1.00 36.48  ? 78  LEU A O   1 
ATOM   622   C CB  . LEU A 1 78  ? 15.108  22.687  2.345   1.00 40.18  ? 78  LEU A CB  1 
ATOM   623   C CG  . LEU A 1 78  ? 13.610  22.456  2.574   1.00 44.97  ? 78  LEU A CG  1 
ATOM   624   C CD1 . LEU A 1 78  ? 13.080  22.968  3.909   1.00 44.24  ? 78  LEU A CD1 1 
ATOM   625   C CD2 . LEU A 1 78  ? 12.878  23.118  1.419   1.00 46.81  ? 78  LEU A CD2 1 
ATOM   626   N N   . PRO A 1 79  ? 17.421  23.466  0.165   1.00 33.98  ? 79  PRO A N   1 
ATOM   627   C CA  . PRO A 1 79  ? 18.745  24.079  0.058   1.00 32.11  ? 79  PRO A CA  1 
ATOM   628   C C   . PRO A 1 79  ? 19.378  24.415  1.401   1.00 34.95  ? 79  PRO A C   1 
ATOM   629   O O   . PRO A 1 79  ? 18.654  24.782  2.338   1.00 35.01  ? 79  PRO A O   1 
ATOM   630   C CB  . PRO A 1 79  ? 18.470  25.349  -0.747  1.00 31.33  ? 79  PRO A CB  1 
ATOM   631   C CG  . PRO A 1 79  ? 17.278  24.985  -1.587  1.00 32.64  ? 79  PRO A CG  1 
ATOM   632   C CD  . PRO A 1 79  ? 16.409  24.176  -0.639  1.00 35.66  ? 79  PRO A CD  1 
ATOM   633   N N   . THR A 1 80  ? 20.724  24.294  1.432   1.00 35.10  ? 80  THR A N   1 
ATOM   634   C CA  . THR A 1 80  ? 21.551  24.493  2.612   1.00 37.05  ? 80  THR A CA  1 
ATOM   635   C C   . THR A 1 80  ? 22.532  25.629  2.338   1.00 39.15  ? 80  THR A C   1 
ATOM   636   O O   . THR A 1 80  ? 22.561  26.175  1.236   1.00 38.61  ? 80  THR A O   1 
ATOM   637   C CB  . THR A 1 80  ? 22.310  23.212  2.947   1.00 38.45  ? 80  THR A CB  1 
ATOM   638   O OG1 . THR A 1 80  ? 23.243  23.174  1.880   1.00 41.17  ? 80  THR A OG1 1 
ATOM   639   C CG2 . THR A 1 80  ? 21.450  21.960  2.998   1.00 38.68  ? 80  THR A CG2 1 
ATOM   640   N N   . ALA A 1 81  ? 23.354  25.974  3.336   1.00 39.14  ? 81  ALA A N   1 
ATOM   641   C CA  . ALA A 1 81  ? 24.472  26.868  3.059   1.00 41.75  ? 81  ALA A CA  1 
ATOM   642   C C   . ALA A 1 81  ? 25.560  26.107  2.287   1.00 40.37  ? 81  ALA A C   1 
ATOM   643   O O   . ALA A 1 81  ? 25.615  24.879  2.314   1.00 38.43  ? 81  ALA A O   1 
ATOM   644   C CB  . ALA A 1 81  ? 24.998  27.461  4.353   1.00 40.78  ? 81  ALA A CB  1 
ATOM   645   N N   . GLU A 1 82  ? 26.437  26.845  1.605   1.00 39.45  ? 82  GLU A N   1 
ATOM   646   C CA  . GLU A 1 82  ? 27.595  26.256  0.941   1.00 43.77  ? 82  GLU A CA  1 
ATOM   647   C C   . GLU A 1 82  ? 28.436  25.450  1.939   1.00 39.14  ? 82  GLU A C   1 
ATOM   648   O O   . GLU A 1 82  ? 28.976  25.993  2.901   1.00 38.76  ? 82  GLU A O   1 
ATOM   649   C CB  . GLU A 1 82  ? 28.379  27.399  0.286   1.00 50.44  ? 82  GLU A CB  1 
ATOM   650   C CG  . GLU A 1 82  ? 29.149  27.024  -0.981  1.00 65.43  ? 82  GLU A CG  1 
ATOM   651   C CD  . GLU A 1 82  ? 29.703  28.260  -1.694  1.00 78.43  ? 82  GLU A CD  1 
ATOM   652   O OE1 . GLU A 1 82  ? 30.932  28.378  -1.936  1.00 71.57  ? 82  GLU A OE1 1 
ATOM   653   O OE2 . GLU A 1 82  ? 28.874  29.157  -1.985  1.00 88.63  ? 82  GLU A OE2 1 
ATOM   654   N N   . GLY A 1 83  ? 28.559  24.140  1.709   1.00 37.33  ? 83  GLY A N   1 
ATOM   655   C CA  . GLY A 1 83  ? 29.402  23.288  2.537   1.00 38.76  ? 83  GLY A CA  1 
ATOM   656   C C   . GLY A 1 83  ? 28.629  22.680  3.705   1.00 45.43  ? 83  GLY A C   1 
ATOM   657   O O   . GLY A 1 83  ? 29.196  21.939  4.518   1.00 44.02  ? 83  GLY A O   1 
ATOM   658   N N   . GLY A 1 84  ? 27.315  22.970  3.747   1.00 51.14  ? 84  GLY A N   1 
ATOM   659   C CA  . GLY A 1 84  ? 26.504  22.788  4.946   1.00 50.42  ? 84  GLY A CA  1 
ATOM   660   C C   . GLY A 1 84  ? 25.456  21.705  4.729   1.00 47.81  ? 84  GLY A C   1 
ATOM   661   O O   . GLY A 1 84  ? 25.190  21.329  3.595   1.00 41.23  ? 84  GLY A O   1 
ATOM   662   N N   . PHE A 1 85  ? 24.882  21.192  5.822   1.00 47.04  ? 85  PHE A N   1 
ATOM   663   C CA  . PHE A 1 85  ? 23.900  20.127  5.701   1.00 45.91  ? 85  PHE A CA  1 
ATOM   664   C C   . PHE A 1 85  ? 22.521  20.612  6.163   1.00 45.10  ? 85  PHE A C   1 
ATOM   665   O O   . PHE A 1 85  ? 21.514  20.159  5.629   1.00 47.22  ? 85  PHE A O   1 
ATOM   666   C CB  . PHE A 1 85  ? 24.377  18.862  6.426   1.00 41.74  ? 85  PHE A CB  1 
ATOM   667   C CG  . PHE A 1 85  ? 23.293  17.801  6.588   1.00 42.63  ? 85  PHE A CG  1 
ATOM   668   C CD1 . PHE A 1 85  ? 23.064  16.860  5.607   1.00 43.23  ? 85  PHE A CD1 1 
ATOM   669   C CD2 . PHE A 1 85  ? 22.488  17.762  7.724   1.00 46.06  ? 85  PHE A CD2 1 
ATOM   670   C CE1 . PHE A 1 85  ? 22.084  15.892  5.773   1.00 50.21  ? 85  PHE A CE1 1 
ATOM   671   C CE2 . PHE A 1 85  ? 21.506  16.800  7.878   1.00 46.73  ? 85  PHE A CE2 1 
ATOM   672   C CZ  . PHE A 1 85  ? 21.304  15.866  6.901   1.00 49.11  ? 85  PHE A CZ  1 
ATOM   673   N N   . GLU A 1 86  ? 22.451  21.517  7.147   1.00 43.07  ? 86  GLU A N   1 
ATOM   674   C CA  . GLU A 1 86  ? 21.163  21.840  7.754   1.00 42.24  ? 86  GLU A CA  1 
ATOM   675   C C   . GLU A 1 86  ? 20.354  22.753  6.830   1.00 36.69  ? 86  GLU A C   1 
ATOM   676   O O   . GLU A 1 86  ? 20.895  23.670  6.212   1.00 35.82  ? 86  GLU A O   1 
ATOM   677   C CB  . GLU A 1 86  ? 21.316  22.499  9.123   1.00 41.21  ? 86  GLU A CB  1 
ATOM   678   C CG  . GLU A 1 86  ? 22.127  21.654  10.100  1.00 39.43  ? 86  GLU A CG  1 
ATOM   679   C CD  . GLU A 1 86  ? 21.397  20.409  10.508  1.00 36.32  ? 86  GLU A CD  1 
ATOM   680   O OE1 . GLU A 1 86  ? 22.066  19.513  11.033  1.00 37.67  ? 86  GLU A OE1 1 
ATOM   681   O OE2 . GLU A 1 86  ? 20.161  20.367  10.331  1.00 38.32  ? 86  GLU A OE2 1 
ATOM   682   N N   . PRO A 1 87  ? 19.029  22.527  6.721   1.00 33.19  ? 87  PRO A N   1 
ATOM   683   C CA  . PRO A 1 87  ? 18.177  23.314  5.835   1.00 34.63  ? 87  PRO A CA  1 
ATOM   684   C C   . PRO A 1 87  ? 18.136  24.784  6.228   1.00 33.90  ? 87  PRO A C   1 
ATOM   685   O O   . PRO A 1 87  ? 17.989  25.114  7.404   1.00 37.66  ? 87  PRO A O   1 
ATOM   686   C CB  . PRO A 1 87  ? 16.812  22.644  6.010   1.00 33.97  ? 87  PRO A CB  1 
ATOM   687   C CG  . PRO A 1 87  ? 16.877  22.093  7.401   1.00 33.84  ? 87  PRO A CG  1 
ATOM   688   C CD  . PRO A 1 87  ? 18.264  21.525  7.475   1.00 34.94  ? 87  PRO A CD  1 
ATOM   689   N N   . LEU A 1 88  ? 18.288  25.658  5.236   1.00 30.52  ? 88  LEU A N   1 
ATOM   690   C CA  . LEU A 1 88  ? 18.152  27.081  5.479   1.00 33.38  ? 88  LEU A CA  1 
ATOM   691   C C   . LEU A 1 88  ? 16.684  27.413  5.749   1.00 34.86  ? 88  LEU A C   1 
ATOM   692   O O   . LEU A 1 88  ? 15.794  26.948  5.028   1.00 34.42  ? 88  LEU A O   1 
ATOM   693   C CB  . LEU A 1 88  ? 18.700  27.904  4.317   1.00 34.48  ? 88  LEU A CB  1 
ATOM   694   C CG  . LEU A 1 88  ? 20.201  27.761  4.045   1.00 37.25  ? 88  LEU A CG  1 
ATOM   695   C CD1 . LEU A 1 88  ? 20.579  28.428  2.731   1.00 37.54  ? 88  LEU A CD1 1 
ATOM   696   C CD2 . LEU A 1 88  ? 21.029  28.320  5.196   1.00 35.34  ? 88  LEU A CD2 1 
ATOM   697   N N   . PRO A 1 89  ? 16.386  28.197  6.818   1.00 35.69  ? 89  PRO A N   1 
ATOM   698   C CA  . PRO A 1 89  ? 15.034  28.711  7.041   1.00 36.32  ? 89  PRO A CA  1 
ATOM   699   C C   . PRO A 1 89  ? 14.465  29.554  5.900   1.00 35.80  ? 89  PRO A C   1 
ATOM   700   O O   . PRO A 1 89  ? 13.261  29.460  5.636   1.00 35.60  ? 89  PRO A O   1 
ATOM   701   C CB  . PRO A 1 89  ? 15.140  29.482  8.360   1.00 37.10  ? 89  PRO A CB  1 
ATOM   702   C CG  . PRO A 1 89  ? 16.619  29.738  8.527   1.00 36.30  ? 89  PRO A CG  1 
ATOM   703   C CD  . PRO A 1 89  ? 17.300  28.536  7.916   1.00 34.48  ? 89  PRO A CD  1 
ATOM   704   N N   . GLU A 1 90  ? 15.324  30.310  5.191   1.00 31.83  ? 90  GLU A N   1 
ATOM   705   C CA  . GLU A 1 90  ? 14.854  31.065  4.033   1.00 32.88  ? 90  GLU A CA  1 
ATOM   706   C C   . GLU A 1 90  ? 14.057  30.168  3.078   1.00 35.25  ? 90  GLU A C   1 
ATOM   707   O O   . GLU A 1 90  ? 12.996  30.579  2.611   1.00 39.06  ? 90  GLU A O   1 
ATOM   708   C CB  . GLU A 1 90  ? 15.976  31.781  3.280   1.00 32.84  ? 90  GLU A CB  1 
ATOM   709   C CG  . GLU A 1 90  ? 16.688  32.821  4.137   1.00 30.45  ? 90  GLU A CG  1 
ATOM   710   C CD  . GLU A 1 90  ? 17.861  32.258  4.918   1.00 29.68  ? 90  GLU A CD  1 
ATOM   711   O OE1 . GLU A 1 90  ? 18.877  32.957  4.882   1.00 29.07  ? 90  GLU A OE1 1 
ATOM   712   O OE2 . GLU A 1 90  ? 17.788  31.173  5.534   1.00 28.77  ? 90  GLU A OE2 1 
ATOM   713   N N   . GLY A 1 91  ? 14.562  28.951  2.797   1.00 33.53  ? 91  GLY A N   1 
ATOM   714   C CA  . GLY A 1 91  ? 13.910  27.987  1.913   1.00 32.37  ? 91  GLY A CA  1 
ATOM   715   C C   . GLY A 1 91  ? 12.600  27.407  2.456   1.00 33.73  ? 91  GLY A C   1 
ATOM   716   O O   . GLY A 1 91  ? 11.609  27.280  1.736   1.00 35.77  ? 91  GLY A O   1 
ATOM   717   N N   . LEU A 1 92  ? 12.593  27.008  3.727   1.00 36.71  ? 92  LEU A N   1 
ATOM   718   C CA  . LEU A 1 92  ? 11.357  26.620  4.382   1.00 36.32  ? 92  LEU A CA  1 
ATOM   719   C C   . LEU A 1 92  ? 10.310  27.724  4.225   1.00 35.27  ? 92  LEU A C   1 
ATOM   720   O O   . LEU A 1 92  ? 9.130   27.438  4.050   1.00 36.75  ? 92  LEU A O   1 
ATOM   721   C CB  . LEU A 1 92  ? 11.647  26.328  5.850   1.00 37.53  ? 92  LEU A CB  1 
ATOM   722   C CG  . LEU A 1 92  ? 10.404  26.144  6.714   1.00 40.84  ? 92  LEU A CG  1 
ATOM   723   C CD1 . LEU A 1 92  ? 9.660   24.863  6.369   1.00 41.67  ? 92  LEU A CD1 1 
ATOM   724   C CD2 . LEU A 1 92  ? 10.819  26.177  8.144   1.00 45.15  ? 92  LEU A CD2 1 
ATOM   725   N N   . TRP A 1 93  ? 10.740  28.986  4.323   1.00 34.04  ? 93  TRP A N   1 
ATOM   726   C CA  . TRP A 1 93  ? 9.818   30.100  4.236   1.00 34.24  ? 93  TRP A CA  1 
ATOM   727   C C   . TRP A 1 93  ? 9.122   30.134  2.868   1.00 33.61  ? 93  TRP A C   1 
ATOM   728   O O   . TRP A 1 93  ? 7.938   30.461  2.768   1.00 31.13  ? 93  TRP A O   1 
ATOM   729   C CB  . TRP A 1 93  ? 10.539  31.427  4.514   1.00 31.43  ? 93  TRP A CB  1 
ATOM   730   C CG  . TRP A 1 93  ? 9.564   32.530  4.823   1.00 29.95  ? 93  TRP A CG  1 
ATOM   731   C CD1 . TRP A 1 93  ? 8.516   32.493  5.696   1.00 28.10  ? 93  TRP A CD1 1 
ATOM   732   C CD2 . TRP A 1 93  ? 9.489   33.809  4.178   1.00 28.41  ? 93  TRP A CD2 1 
ATOM   733   N NE1 . TRP A 1 93  ? 7.836   33.678  5.693   1.00 26.75  ? 93  TRP A NE1 1 
ATOM   734   C CE2 . TRP A 1 93  ? 8.403   34.497  4.758   1.00 27.54  ? 93  TRP A CE2 1 
ATOM   735   C CE3 . TRP A 1 93  ? 10.233  34.427  3.183   1.00 30.01  ? 93  TRP A CE3 1 
ATOM   736   C CZ2 . TRP A 1 93  ? 8.049   35.774  4.366   1.00 27.14  ? 93  TRP A CZ2 1 
ATOM   737   C CZ3 . TRP A 1 93  ? 9.875   35.695  2.791   1.00 30.21  ? 93  TRP A CZ3 1 
ATOM   738   C CH2 . TRP A 1 93  ? 8.796   36.349  3.368   1.00 28.94  ? 93  TRP A CH2 1 
ATOM   739   N N   . TYR A 1 94  ? 9.876   29.818  1.814   1.00 32.03  ? 94  TYR A N   1 
ATOM   740   C CA  . TYR A 1 94  ? 9.323   29.744  0.473   1.00 33.68  ? 94  TYR A CA  1 
ATOM   741   C C   . TYR A 1 94  ? 8.267   28.642  0.435   1.00 30.87  ? 94  TYR A C   1 
ATOM   742   O O   . TYR A 1 94  ? 7.177   28.842  -0.089  1.00 26.83  ? 94  TYR A O   1 
ATOM   743   C CB  . TYR A 1 94  ? 10.470  29.540  -0.525  1.00 37.11  ? 94  TYR A CB  1 
ATOM   744   C CG  . TYR A 1 94  ? 10.129  29.582  -2.016  1.00 41.95  ? 94  TYR A CG  1 
ATOM   745   C CD1 . TYR A 1 94  ? 9.632   28.453  -2.658  1.00 42.05  ? 94  TYR A CD1 1 
ATOM   746   C CD2 . TYR A 1 94  ? 10.355  30.720  -2.792  1.00 40.82  ? 94  TYR A CD2 1 
ATOM   747   C CE1 . TYR A 1 94  ? 9.336   28.461  -4.009  1.00 42.63  ? 94  TYR A CE1 1 
ATOM   748   C CE2 . TYR A 1 94  ? 10.051  30.744  -4.144  1.00 40.80  ? 94  TYR A CE2 1 
ATOM   749   C CZ  . TYR A 1 94  ? 9.560   29.602  -4.759  1.00 43.34  ? 94  TYR A CZ  1 
ATOM   750   O OH  . TYR A 1 94  ? 9.242   29.556  -6.088  1.00 40.81  ? 94  TYR A OH  1 
ATOM   751   N N   . LEU A 1 95  ? 8.590   27.490  1.029   1.00 32.52  ? 95  LEU A N   1 
ATOM   752   C CA  . LEU A 1 95  ? 7.699   26.345  1.013   1.00 31.46  ? 95  LEU A CA  1 
ATOM   753   C C   . LEU A 1 95  ? 6.389   26.708  1.722   1.00 34.36  ? 95  LEU A C   1 
ATOM   754   O O   . LEU A 1 95  ? 5.308   26.526  1.160   1.00 32.24  ? 95  LEU A O   1 
ATOM   755   C CB  . LEU A 1 95  ? 8.417   25.135  1.605   1.00 31.37  ? 95  LEU A CB  1 
ATOM   756   C CG  . LEU A 1 95  ? 7.541   23.906  1.877   1.00 33.87  ? 95  LEU A CG  1 
ATOM   757   C CD1 . LEU A 1 95  ? 6.786   23.485  0.642   1.00 33.54  ? 95  LEU A CD1 1 
ATOM   758   C CD2 . LEU A 1 95  ? 8.339   22.728  2.402   1.00 33.15  ? 95  LEU A CD2 1 
ATOM   759   N N   . LEU A 1 96  ? 6.481   27.278  2.933   1.00 35.52  ? 96  LEU A N   1 
ATOM   760   C CA  . LEU A 1 96  ? 5.305   27.725  3.680   1.00 33.22  ? 96  LEU A CA  1 
ATOM   761   C C   . LEU A 1 96  ? 4.381   28.599  2.814   1.00 33.25  ? 96  LEU A C   1 
ATOM   762   O O   . LEU A 1 96  ? 3.165   28.402  2.765   1.00 32.59  ? 96  LEU A O   1 
ATOM   763   C CB  . LEU A 1 96  ? 5.728   28.446  4.964   1.00 30.25  ? 96  LEU A CB  1 
ATOM   764   C CG  . LEU A 1 96  ? 6.459   27.611  6.027   1.00 29.62  ? 96  LEU A CG  1 
ATOM   765   C CD1 . LEU A 1 96  ? 6.454   28.319  7.388   1.00 27.52  ? 96  LEU A CD1 1 
ATOM   766   C CD2 . LEU A 1 96  ? 5.900   26.183  6.169   1.00 29.54  ? 96  LEU A CD2 1 
ATOM   767   N N   . LEU A 1 97  ? 4.949   29.549  2.080   1.00 31.02  ? 97  LEU A N   1 
ATOM   768   C CA  . LEU A 1 97  ? 4.128   30.469  1.323   1.00 30.51  ? 97  LEU A CA  1 
ATOM   769   C C   . LEU A 1 97  ? 3.570   29.883  0.015   1.00 33.18  ? 97  LEU A C   1 
ATOM   770   O O   . LEU A 1 97  ? 2.436   30.200  -0.335  1.00 33.13  ? 97  LEU A O   1 
ATOM   771   C CB  . LEU A 1 97  ? 5.013   31.693  1.124   1.00 31.79  ? 97  LEU A CB  1 
ATOM   772   C CG  . LEU A 1 97  ? 5.027   32.667  2.306   1.00 34.25  ? 97  LEU A CG  1 
ATOM   773   C CD1 . LEU A 1 97  ? 6.190   33.651  2.209   1.00 35.84  ? 97  LEU A CD1 1 
ATOM   774   C CD2 . LEU A 1 97  ? 3.701   33.407  2.343   1.00 33.11  ? 97  LEU A CD2 1 
ATOM   775   N N   . THR A 1 98  ? 4.341   29.071  -0.733  1.00 34.23  ? 98  THR A N   1 
ATOM   776   C CA  . THR A 1 98  ? 3.952   28.623  -2.074  1.00 34.76  ? 98  THR A CA  1 
ATOM   777   C C   . THR A 1 98  ? 3.444   27.180  -2.112  1.00 34.51  ? 98  THR A C   1 
ATOM   778   O O   . THR A 1 98  ? 2.891   26.733  -3.113  1.00 39.56  ? 98  THR A O   1 
ATOM   779   C CB  . THR A 1 98  ? 5.142   28.719  -3.027  1.00 34.61  ? 98  THR A CB  1 
ATOM   780   O OG1 . THR A 1 98  ? 6.118   27.782  -2.577  1.00 35.94  ? 98  THR A OG1 1 
ATOM   781   C CG2 . THR A 1 98  ? 5.707   30.120  -3.067  1.00 38.19  ? 98  THR A CG2 1 
ATOM   782   N N   . GLY A 1 99  ? 3.756   26.407  -1.081  1.00 33.21  ? 99  GLY A N   1 
ATOM   783   C CA  . GLY A 1 99  ? 3.483   24.991  -1.112  1.00 31.66  ? 99  GLY A CA  1 
ATOM   784   C C   . GLY A 1 99  ? 4.458   24.276  -2.023  1.00 32.88  ? 99  GLY A C   1 
ATOM   785   O O   . GLY A 1 99  ? 4.301   23.086  -2.253  1.00 32.53  ? 99  GLY A O   1 
ATOM   786   N N   . GLU A 1 100 ? 5.496   24.989  -2.482  1.00 40.97  ? 100 GLU A N   1 
ATOM   787   C CA  . GLU A 1 100 ? 6.384   24.469  -3.518  1.00 39.75  ? 100 GLU A CA  1 
ATOM   788   C C   . GLU A 1 100 ? 7.824   24.490  -3.011  1.00 36.33  ? 100 GLU A C   1 
ATOM   789   O O   . GLU A 1 100 ? 8.214   25.429  -2.327  1.00 38.26  ? 100 GLU A O   1 
ATOM   790   C CB  . GLU A 1 100 ? 6.260   25.285  -4.807  1.00 41.41  ? 100 GLU A CB  1 
ATOM   791   C CG  . GLU A 1 100 ? 4.944   25.109  -5.559  1.00 42.70  ? 100 GLU A CG  1 
ATOM   792   C CD  . GLU A 1 100 ? 4.695   26.060  -6.725  1.00 43.09  ? 100 GLU A CD  1 
ATOM   793   O OE1 . GLU A 1 100 ? 3.675   25.804  -7.387  1.00 47.21  ? 100 GLU A OE1 1 
ATOM   794   O OE2 . GLU A 1 100 ? 5.439   27.032  -6.983  1.00 38.81  ? 100 GLU A OE2 1 
ATOM   795   N N   . LEU A 1 101 ? 8.607   23.468  -3.377  1.00 33.84  ? 101 LEU A N   1 
ATOM   796   C CA  . LEU A 1 101 ? 10.001  23.392  -2.981  1.00 37.52  ? 101 LEU A CA  1 
ATOM   797   C C   . LEU A 1 101 ? 10.811  24.420  -3.769  1.00 38.84  ? 101 LEU A C   1 
ATOM   798   O O   . LEU A 1 101 ? 10.704  24.503  -4.988  1.00 41.70  ? 101 LEU A O   1 
ATOM   799   C CB  . LEU A 1 101 ? 10.529  21.974  -3.172  1.00 38.69  ? 101 LEU A CB  1 
ATOM   800   C CG  . LEU A 1 101 ? 9.926   20.925  -2.233  1.00 41.48  ? 101 LEU A CG  1 
ATOM   801   C CD1 . LEU A 1 101 ? 10.288  19.526  -2.682  1.00 43.17  ? 101 LEU A CD1 1 
ATOM   802   C CD2 . LEU A 1 101 ? 10.349  21.133  -0.791  1.00 40.39  ? 101 LEU A CD2 1 
ATOM   803   N N   . PRO A 1 102 ? 11.653  25.234  -3.096  1.00 40.19  ? 102 PRO A N   1 
ATOM   804   C CA  . PRO A 1 102 ? 12.481  26.234  -3.775  1.00 41.00  ? 102 PRO A CA  1 
ATOM   805   C C   . PRO A 1 102 ? 13.752  25.650  -4.380  1.00 39.19  ? 102 PRO A C   1 
ATOM   806   O O   . PRO A 1 102 ? 14.251  24.629  -3.911  1.00 38.68  ? 102 PRO A O   1 
ATOM   807   C CB  . PRO A 1 102 ? 12.814  27.169  -2.613  1.00 40.87  ? 102 PRO A CB  1 
ATOM   808   C CG  . PRO A 1 102 ? 13.022  26.211  -1.468  1.00 40.00  ? 102 PRO A CG  1 
ATOM   809   C CD  . PRO A 1 102 ? 11.902  25.197  -1.646  1.00 40.90  ? 102 PRO A CD  1 
ATOM   810   N N   . THR A 1 103 ? 14.272  26.346  -5.392  1.00 40.01  ? 103 THR A N   1 
ATOM   811   C CA  . THR A 1 103 ? 15.604  26.090  -5.906  1.00 46.60  ? 103 THR A CA  1 
ATOM   812   C C   . THR A 1 103 ? 16.618  26.828  -5.035  1.00 51.75  ? 103 THR A C   1 
ATOM   813   O O   . THR A 1 103 ? 16.253  27.692  -4.235  1.00 49.03  ? 103 THR A O   1 
ATOM   814   C CB  . THR A 1 103 ? 15.697  26.550  -7.365  1.00 51.74  ? 103 THR A CB  1 
ATOM   815   O OG1 . THR A 1 103 ? 15.639  27.979  -7.384  1.00 53.48  ? 103 THR A OG1 1 
ATOM   816   C CG2 . THR A 1 103 ? 14.613  25.941  -8.240  1.00 49.89  ? 103 THR A CG2 1 
ATOM   817   N N   . GLU A 1 104 ? 17.902  26.492  -5.222  1.00 59.16  ? 104 GLU A N   1 
ATOM   818   C CA  . GLU A 1 104 ? 19.003  27.302  -4.721  1.00 57.64  ? 104 GLU A CA  1 
ATOM   819   C C   . GLU A 1 104 ? 18.752  28.784  -4.975  1.00 53.82  ? 104 GLU A C   1 
ATOM   820   O O   . GLU A 1 104 ? 18.866  29.581  -4.054  1.00 53.13  ? 104 GLU A O   1 
ATOM   821   C CB  . GLU A 1 104 ? 20.302  26.943  -5.427  1.00 64.32  ? 104 GLU A CB  1 
ATOM   822   C CG  . GLU A 1 104 ? 21.031  25.777  -4.775  1.00 71.31  ? 104 GLU A CG  1 
ATOM   823   C CD  . GLU A 1 104 ? 21.884  26.226  -3.613  1.00 75.31  ? 104 GLU A CD  1 
ATOM   824   O OE1 . GLU A 1 104 ? 21.761  25.608  -2.529  1.00 78.68  ? 104 GLU A OE1 1 
ATOM   825   O OE2 . GLU A 1 104 ? 22.653  27.199  -3.810  1.00 66.08  ? 104 GLU A OE2 1 
ATOM   826   N N   . GLU A 1 105 ? 18.424  29.137  -6.226  1.00 57.38  ? 105 GLU A N   1 
ATOM   827   C CA  . GLU A 1 105 ? 18.248  30.532  -6.633  1.00 63.54  ? 105 GLU A CA  1 
ATOM   828   C C   . GLU A 1 105 ? 17.078  31.195  -5.897  1.00 56.99  ? 105 GLU A C   1 
ATOM   829   O O   . GLU A 1 105 ? 17.141  32.386  -5.575  1.00 46.90  ? 105 GLU A O   1 
ATOM   830   C CB  . GLU A 1 105 ? 18.054  30.727  -8.145  1.00 66.40  ? 105 GLU A CB  1 
ATOM   831   C CG  . GLU A 1 105 ? 19.276  31.316  -8.858  1.00 81.21  ? 105 GLU A CG  1 
ATOM   832   C CD  . GLU A 1 105 ? 19.755  32.692  -8.381  1.00 90.61  ? 105 GLU A CD  1 
ATOM   833   O OE1 . GLU A 1 105 ? 20.904  32.791  -7.870  1.00 84.87  ? 105 GLU A OE1 1 
ATOM   834   O OE2 . GLU A 1 105 ? 18.984  33.678  -8.518  1.00 89.17  ? 105 GLU A OE2 1 
ATOM   835   N N   . ASP A 1 106 ? 15.998  30.435  -5.670  1.00 53.08  ? 106 ASP A N   1 
ATOM   836   C CA  . ASP A 1 106 ? 14.842  30.945  -4.949  1.00 50.83  ? 106 ASP A CA  1 
ATOM   837   C C   . ASP A 1 106 ? 15.253  31.351  -3.541  1.00 47.57  ? 106 ASP A C   1 
ATOM   838   O O   . ASP A 1 106 ? 14.798  32.387  -3.054  1.00 42.76  ? 106 ASP A O   1 
ATOM   839   C CB  . ASP A 1 106 ? 13.717  29.926  -4.918  1.00 51.65  ? 106 ASP A CB  1 
ATOM   840   C CG  . ASP A 1 106 ? 13.187  29.574  -6.295  1.00 45.57  ? 106 ASP A CG  1 
ATOM   841   O OD1 . ASP A 1 106 ? 13.405  30.394  -7.189  1.00 44.00  ? 106 ASP A OD1 1 
ATOM   842   O OD2 . ASP A 1 106 ? 12.633  28.467  -6.461  1.00 43.80  ? 106 ASP A OD2 1 
ATOM   843   N N   . VAL A 1 107 ? 16.126  30.533  -2.924  1.00 43.86  ? 107 VAL A N   1 
ATOM   844   C CA  . VAL A 1 107 ? 16.555  30.751  -1.553  1.00 45.10  ? 107 VAL A CA  1 
ATOM   845   C C   . VAL A 1 107 ? 17.503  31.948  -1.486  1.00 45.05  ? 107 VAL A C   1 
ATOM   846   O O   . VAL A 1 107 ? 17.342  32.819  -0.646  1.00 44.26  ? 107 VAL A O   1 
ATOM   847   C CB  . VAL A 1 107 ? 17.161  29.469  -0.958  1.00 46.36  ? 107 VAL A CB  1 
ATOM   848   C CG1 . VAL A 1 107 ? 17.892  29.740  0.350   1.00 53.56  ? 107 VAL A CG1 1 
ATOM   849   C CG2 . VAL A 1 107 ? 16.086  28.416  -0.738  1.00 44.90  ? 107 VAL A CG2 1 
ATOM   850   N N   . LYS A 1 108 ? 18.464  32.027  -2.400  1.00 48.34  ? 108 LYS A N   1 
ATOM   851   C CA  . LYS A 1 108 ? 19.396  33.137  -2.393  1.00 49.54  ? 108 LYS A CA  1 
ATOM   852   C C   . LYS A 1 108 ? 18.669  34.464  -2.651  1.00 45.58  ? 108 LYS A C   1 
ATOM   853   O O   . LYS A 1 108 ? 19.107  35.503  -2.157  1.00 42.10  ? 108 LYS A O   1 
ATOM   854   C CB  . LYS A 1 108 ? 20.583  32.801  -3.309  1.00 56.60  ? 108 LYS A CB  1 
ATOM   855   C CG  . LYS A 1 108 ? 21.562  31.786  -2.703  1.00 63.89  ? 108 LYS A CG  1 
ATOM   856   C CD  . LYS A 1 108 ? 23.011  31.897  -3.182  1.00 75.09  ? 108 LYS A CD  1 
ATOM   857   C CE  . LYS A 1 108 ? 23.284  31.423  -4.583  1.00 77.46  ? 108 LYS A CE  1 
ATOM   858   N NZ  . LYS A 1 108 ? 23.248  29.960  -4.706  1.00 76.01  ? 108 LYS A NZ  1 
ATOM   859   N N   . GLU A 1 109 ? 17.534  34.453  -3.372  1.00 48.01  ? 109 GLU A N   1 
ATOM   860   C CA  . GLU A 1 109 ? 16.769  35.685  -3.583  1.00 47.20  ? 109 GLU A CA  1 
ATOM   861   C C   . GLU A 1 109 ? 16.258  36.227  -2.250  1.00 45.34  ? 109 GLU A C   1 
ATOM   862   O O   . GLU A 1 109 ? 16.269  37.433  -2.032  1.00 40.65  ? 109 GLU A O   1 
ATOM   863   C CB  . GLU A 1 109 ? 15.591  35.587  -4.556  1.00 45.19  ? 109 GLU A CB  1 
ATOM   864   C CG  . GLU A 1 109 ? 16.051  35.621  -6.014  1.00 50.95  ? 109 GLU A CG  1 
ATOM   865   C CD  . GLU A 1 109 ? 14.998  35.492  -7.100  1.00 49.74  ? 109 GLU A CD  1 
ATOM   866   O OE1 . GLU A 1 109 ? 15.379  35.640  -8.273  1.00 50.14  ? 109 GLU A OE1 1 
ATOM   867   O OE2 . GLU A 1 109 ? 13.815  35.259  -6.784  1.00 53.03  ? 109 GLU A OE2 1 
ATOM   868   N N   . ILE A 1 110 ? 15.847  35.308  -1.366  1.00 43.05  ? 110 ILE A N   1 
ATOM   869   C CA  . ILE A 1 110 ? 15.241  35.635  -0.093  1.00 36.54  ? 110 ILE A CA  1 
ATOM   870   C C   . ILE A 1 110 ? 16.352  36.065  0.858   1.00 36.04  ? 110 ILE A C   1 
ATOM   871   O O   . ILE A 1 110 ? 16.237  37.094  1.516   1.00 31.99  ? 110 ILE A O   1 
ATOM   872   C CB  . ILE A 1 110 ? 14.419  34.427  0.385   1.00 36.31  ? 110 ILE A CB  1 
ATOM   873   C CG1 . ILE A 1 110 ? 13.272  34.169  -0.590  1.00 37.99  ? 110 ILE A CG1 1 
ATOM   874   C CG2 . ILE A 1 110 ? 13.902  34.593  1.812   1.00 37.21  ? 110 ILE A CG2 1 
ATOM   875   C CD1 . ILE A 1 110 ? 12.549  32.847  -0.399  1.00 39.91  ? 110 ILE A CD1 1 
ATOM   876   N N   . SER A 1 111 ? 17.452  35.307  0.870   1.00 35.57  ? 111 SER A N   1 
ATOM   877   C CA  . SER A 1 111 ? 18.619  35.672  1.659   1.00 38.23  ? 111 SER A CA  1 
ATOM   878   C C   . SER A 1 111 ? 19.118  37.075  1.293   1.00 36.36  ? 111 SER A C   1 
ATOM   879   O O   . SER A 1 111 ? 19.449  37.849  2.182   1.00 31.06  ? 111 SER A O   1 
ATOM   880   C CB  . SER A 1 111 ? 19.733  34.646  1.516   1.00 41.66  ? 111 SER A CB  1 
ATOM   881   O OG  . SER A 1 111 ? 19.388  33.379  2.072   1.00 43.04  ? 111 SER A OG  1 
ATOM   882   N N   . ALA A 1 112 ? 19.158  37.391  -0.010  1.00 35.97  ? 112 ALA A N   1 
ATOM   883   C CA  . ALA A 1 112 ? 19.574  38.703  -0.488  1.00 38.93  ? 112 ALA A CA  1 
ATOM   884   C C   . ALA A 1 112 ? 18.649  39.805  0.035   1.00 42.57  ? 112 ALA A C   1 
ATOM   885   O O   . ALA A 1 112 ? 19.083  40.921  0.342   1.00 46.07  ? 112 ALA A O   1 
ATOM   886   C CB  . ALA A 1 112 ? 19.588  38.708  -2.001  1.00 34.48  ? 112 ALA A CB  1 
ATOM   887   N N   . GLU A 1 113 ? 17.352  39.488  0.090   1.00 44.40  ? 113 GLU A N   1 
ATOM   888   C CA  . GLU A 1 113 ? 16.328  40.457  0.432   1.00 39.88  ? 113 GLU A CA  1 
ATOM   889   C C   . GLU A 1 113 ? 16.428  40.778  1.924   1.00 38.56  ? 113 GLU A C   1 
ATOM   890   O O   . GLU A 1 113 ? 16.386  41.942  2.300   1.00 35.93  ? 113 GLU A O   1 
ATOM   891   C CB  . GLU A 1 113 ? 15.028  39.811  -0.030  1.00 40.29  ? 113 GLU A CB  1 
ATOM   892   C CG  . GLU A 1 113 ? 13.939  40.816  -0.349  1.00 46.22  ? 113 GLU A CG  1 
ATOM   893   C CD  . GLU A 1 113 ? 14.200  41.711  -1.537  1.00 44.73  ? 113 GLU A CD  1 
ATOM   894   O OE1 . GLU A 1 113 ? 14.302  42.943  -1.376  1.00 49.60  ? 113 GLU A OE1 1 
ATOM   895   O OE2 . GLU A 1 113 ? 14.270  41.146  -2.629  1.00 47.31  ? 113 GLU A OE2 1 
ATOM   896   N N   . PHE A 1 114 ? 16.610  39.732  2.748   1.00 37.13  ? 114 PHE A N   1 
ATOM   897   C CA  . PHE A 1 114 ? 16.798  39.861  4.184   1.00 38.42  ? 114 PHE A CA  1 
ATOM   898   C C   . PHE A 1 114 ? 18.065  40.663  4.481   1.00 43.16  ? 114 PHE A C   1 
ATOM   899   O O   . PHE A 1 114 ? 18.046  41.552  5.324   1.00 47.80  ? 114 PHE A O   1 
ATOM   900   C CB  . PHE A 1 114 ? 16.858  38.501  4.891   1.00 38.21  ? 114 PHE A CB  1 
ATOM   901   C CG  . PHE A 1 114 ? 15.557  37.693  4.983   1.00 40.08  ? 114 PHE A CG  1 
ATOM   902   C CD1 . PHE A 1 114 ? 14.304  38.281  4.800   1.00 36.60  ? 114 PHE A CD1 1 
ATOM   903   C CD2 . PHE A 1 114 ? 15.585  36.333  5.301   1.00 36.62  ? 114 PHE A CD2 1 
ATOM   904   C CE1 . PHE A 1 114 ? 13.142  37.527  4.921   1.00 36.64  ? 114 PHE A CE1 1 
ATOM   905   C CE2 . PHE A 1 114 ? 14.420  35.580  5.384   1.00 32.37  ? 114 PHE A CE2 1 
ATOM   906   C CZ  . PHE A 1 114 ? 13.203  36.175  5.206   1.00 35.41  ? 114 PHE A CZ  1 
ATOM   907   N N   . THR A 1 115 ? 19.158  40.347  3.783   1.00 45.48  ? 115 THR A N   1 
ATOM   908   C CA  . THR A 1 115 ? 20.456  40.962  4.020   1.00 44.15  ? 115 THR A CA  1 
ATOM   909   C C   . THR A 1 115 ? 20.420  42.455  3.678   1.00 40.22  ? 115 THR A C   1 
ATOM   910   O O   . THR A 1 115 ? 20.929  43.269  4.435   1.00 45.27  ? 115 THR A O   1 
ATOM   911   C CB  . THR A 1 115 ? 21.514  40.167  3.243   1.00 48.52  ? 115 THR A CB  1 
ATOM   912   O OG1 . THR A 1 115 ? 22.012  39.234  4.205   1.00 49.94  ? 115 THR A OG1 1 
ATOM   913   C CG2 . THR A 1 115 ? 22.635  41.011  2.661   1.00 46.03  ? 115 THR A CG2 1 
ATOM   914   N N   . LYS A 1 116 ? 19.808  42.819  2.556   1.00 38.66  ? 116 LYS A N   1 
ATOM   915   C CA  . LYS A 1 116 ? 19.644  44.216  2.184   1.00 40.62  ? 116 LYS A CA  1 
ATOM   916   C C   . LYS A 1 116 ? 18.747  44.966  3.184   1.00 38.78  ? 116 LYS A C   1 
ATOM   917   O O   . LYS A 1 116 ? 18.974  46.129  3.486   1.00 39.77  ? 116 LYS A O   1 
ATOM   918   C CB  . LYS A 1 116 ? 19.138  44.245  0.733   1.00 47.70  ? 116 LYS A CB  1 
ATOM   919   C CG  . LYS A 1 116 ? 18.400  45.521  0.319   1.00 60.06  ? 116 LYS A CG  1 
ATOM   920   C CD  . LYS A 1 116 ? 17.759  45.531  -1.072  1.00 68.50  ? 116 LYS A CD  1 
ATOM   921   C CE  . LYS A 1 116 ? 17.154  46.874  -1.396  1.00 72.42  ? 116 LYS A CE  1 
ATOM   922   N NZ  . LYS A 1 116 ? 16.977  47.078  -2.836  1.00 76.40  ? 116 LYS A NZ  1 
ATOM   923   N N   . ARG A 1 117 ? 17.719  44.314  3.725   1.00 39.76  ? 117 ARG A N   1 
ATOM   924   C CA  . ARG A 1 117 ? 16.761  44.990  4.589   1.00 37.49  ? 117 ARG A CA  1 
ATOM   925   C C   . ARG A 1 117 ? 17.155  44.982  6.076   1.00 33.45  ? 117 ARG A C   1 
ATOM   926   O O   . ARG A 1 117 ? 16.553  45.707  6.867   1.00 28.15  ? 117 ARG A O   1 
ATOM   927   C CB  . ARG A 1 117 ? 15.391  44.342  4.379   1.00 37.78  ? 117 ARG A CB  1 
ATOM   928   C CG  . ARG A 1 117 ? 14.779  44.612  3.013   1.00 37.55  ? 117 ARG A CG  1 
ATOM   929   C CD  . ARG A 1 117 ? 13.621  43.657  2.761   1.00 40.18  ? 117 ARG A CD  1 
ATOM   930   N NE  . ARG A 1 117 ? 13.194  43.702  1.360   1.00 40.48  ? 117 ARG A NE  1 
ATOM   931   C CZ  . ARG A 1 117 ? 12.080  44.239  0.912   1.00 40.77  ? 117 ARG A CZ  1 
ATOM   932   N NH1 . ARG A 1 117 ? 11.362  45.048  1.669   1.00 45.36  ? 117 ARG A NH1 1 
ATOM   933   N NH2 . ARG A 1 117 ? 11.693  43.977  -0.314  1.00 42.24  ? 117 ARG A NH2 1 
ATOM   934   N N   . MET A 1 118 ? 18.182  44.222  6.481   1.00 33.59  ? 118 MET A N   1 
ATOM   935   C CA  . MET A 1 118 ? 18.580  44.303  7.877   1.00 36.41  ? 118 MET A CA  1 
ATOM   936   C C   . MET A 1 118 ? 19.329  45.603  8.135   1.00 38.01  ? 118 MET A C   1 
ATOM   937   O O   . MET A 1 118 ? 19.511  45.989  9.291   1.00 34.71  ? 118 MET A O   1 
ATOM   938   C CB  . MET A 1 118 ? 19.335  43.082  8.411   1.00 38.58  ? 118 MET A CB  1 
ATOM   939   C CG  . MET A 1 118 ? 20.532  42.568  7.657   1.00 44.88  ? 118 MET A CG  1 
ATOM   940   S SD  . MET A 1 118 ? 21.040  41.110  8.599   1.00 55.99  ? 118 MET A SD  1 
ATOM   941   C CE  . MET A 1 118 ? 19.860  39.772  8.314   1.00 54.14  ? 118 MET A CE  1 
ATOM   942   N N   . GLN A 1 119 ? 19.671  46.313  7.050   1.00 42.39  ? 119 GLN A N   1 
ATOM   943   C CA  . GLN A 1 119 ? 20.368  47.583  7.152   1.00 45.21  ? 119 GLN A CA  1 
ATOM   944   C C   . GLN A 1 119 ? 19.357  48.697  7.385   1.00 43.71  ? 119 GLN A C   1 
ATOM   945   O O   . GLN A 1 119 ? 19.767  49.860  7.463   1.00 41.32  ? 119 GLN A O   1 
ATOM   946   C CB  . GLN A 1 119 ? 21.131  47.980  5.882   1.00 51.83  ? 119 GLN A CB  1 
ATOM   947   C CG  . GLN A 1 119 ? 22.303  47.078  5.498   1.00 55.49  ? 119 GLN A CG  1 
ATOM   948   C CD  . GLN A 1 119 ? 23.317  46.885  6.605   1.00 61.01  ? 119 GLN A CD  1 
ATOM   949   O OE1 . GLN A 1 119 ? 23.690  47.827  7.315   1.00 62.17  ? 119 GLN A OE1 1 
ATOM   950   N NE2 . GLN A 1 119 ? 23.770  45.648  6.766   1.00 64.78  ? 119 GLN A NE2 1 
ATOM   951   N N   . ASN A 1 120 ? 18.057  48.327  7.435   1.00 39.15  ? 120 ASN A N   1 
ATOM   952   C CA  . ASN A 1 120 ? 16.961  49.290  7.438   1.00 36.99  ? 120 ASN A CA  1 
ATOM   953   C C   . ASN A 1 120 ? 16.188  49.294  8.767   1.00 31.28  ? 120 ASN A C   1 
ATOM   954   O O   . ASN A 1 120 ? 15.026  49.720  8.793   1.00 31.08  ? 120 ASN A O   1 
ATOM   955   C CB  . ASN A 1 120 ? 15.988  49.027  6.289   1.00 39.57  ? 120 ASN A CB  1 
ATOM   956   C CG  . ASN A 1 120 ? 16.570  49.241  4.902   1.00 44.81  ? 120 ASN A CG  1 
ATOM   957   O OD1 . ASN A 1 120 ? 16.071  48.650  3.934   1.00 38.89  ? 120 ASN A OD1 1 
ATOM   958   N ND2 . ASN A 1 120 ? 17.602  50.062  4.765   1.00 43.51  ? 120 ASN A ND2 1 
ATOM   959   N N   . VAL A 1 121 ? 16.809  48.849  9.875   1.00 27.15  ? 121 VAL A N   1 
ATOM   960   C CA  . VAL A 1 121 ? 16.156  48.979  11.174  1.00 24.22  ? 121 VAL A CA  1 
ATOM   961   C C   . VAL A 1 121 ? 16.220  50.439  11.604  1.00 21.58  ? 121 VAL A C   1 
ATOM   962   O O   . VAL A 1 121 ? 17.267  51.048  11.680  1.00 24.78  ? 121 VAL A O   1 
ATOM   963   C CB  . VAL A 1 121 ? 16.716  48.053  12.258  1.00 24.08  ? 121 VAL A CB  1 
ATOM   964   C CG1 . VAL A 1 121 ? 15.929  48.197  13.537  1.00 24.81  ? 121 VAL A CG1 1 
ATOM   965   C CG2 . VAL A 1 121 ? 16.684  46.601  11.803  1.00 26.47  ? 121 VAL A CG2 1 
ATOM   966   N N   . PRO A 1 122 ? 15.086  51.118  11.792  1.00 21.43  ? 122 PRO A N   1 
ATOM   967   C CA  . PRO A 1 122 ? 15.129  52.540  12.135  1.00 24.02  ? 122 PRO A CA  1 
ATOM   968   C C   . PRO A 1 122 ? 15.988  52.816  13.374  1.00 29.08  ? 122 PRO A C   1 
ATOM   969   O O   . PRO A 1 122 ? 16.003  52.003  14.303  1.00 31.13  ? 122 PRO A O   1 
ATOM   970   C CB  . PRO A 1 122 ? 13.671  52.879  12.398  1.00 23.20  ? 122 PRO A CB  1 
ATOM   971   C CG  . PRO A 1 122 ? 12.896  51.789  11.719  1.00 22.78  ? 122 PRO A CG  1 
ATOM   972   C CD  . PRO A 1 122 ? 13.742  50.551  11.690  1.00 21.07  ? 122 PRO A CD  1 
ATOM   973   N N   . GLN A 1 123 ? 16.655  53.977  13.407  1.00 31.30  ? 123 GLN A N   1 
ATOM   974   C CA  . GLN A 1 123 ? 17.439  54.394  14.568  1.00 35.76  ? 123 GLN A CA  1 
ATOM   975   C C   . GLN A 1 123 ? 16.545  54.439  15.820  1.00 30.34  ? 123 GLN A C   1 
ATOM   976   O O   . GLN A 1 123 ? 16.988  54.067  16.900  1.00 29.29  ? 123 GLN A O   1 
ATOM   977   C CB  . GLN A 1 123 ? 18.227  55.675  14.219  1.00 38.09  ? 123 GLN A CB  1 
ATOM   978   C CG  . GLN A 1 123 ? 19.229  56.182  15.258  1.00 45.47  ? 123 GLN A CG  1 
ATOM   979   C CD  . GLN A 1 123 ? 20.158  55.128  15.854  1.00 59.08  ? 123 GLN A CD  1 
ATOM   980   O OE1 . GLN A 1 123 ? 20.775  54.312  15.145  1.00 62.39  ? 123 GLN A OE1 1 
ATOM   981   N NE2 . GLN A 1 123 ? 20.275  55.132  17.182  1.00 59.14  ? 123 GLN A NE2 1 
ATOM   982   N N   . TYR A 1 124 ? 15.280  54.872  15.696  1.00 29.63  ? 124 TYR A N   1 
ATOM   983   C CA  . TYR A 1 124 ? 14.456  55.101  16.882  1.00 30.26  ? 124 TYR A CA  1 
ATOM   984   C C   . TYR A 1 124 ? 14.162  53.779  17.615  1.00 28.30  ? 124 TYR A C   1 
ATOM   985   O O   . TYR A 1 124 ? 13.976  53.770  18.828  1.00 30.60  ? 124 TYR A O   1 
ATOM   986   C CB  . TYR A 1 124 ? 13.199  55.914  16.548  1.00 29.36  ? 124 TYR A CB  1 
ATOM   987   C CG  . TYR A 1 124 ? 12.245  55.215  15.585  1.00 29.42  ? 124 TYR A CG  1 
ATOM   988   C CD1 . TYR A 1 124 ? 11.452  54.156  16.000  1.00 29.07  ? 124 TYR A CD1 1 
ATOM   989   C CD2 . TYR A 1 124 ? 12.101  55.653  14.272  1.00 28.50  ? 124 TYR A CD2 1 
ATOM   990   C CE1 . TYR A 1 124 ? 10.576  53.525  15.129  1.00 31.48  ? 124 TYR A CE1 1 
ATOM   991   C CE2 . TYR A 1 124 ? 11.255  55.012  13.386  1.00 29.00  ? 124 TYR A CE2 1 
ATOM   992   C CZ  . TYR A 1 124 ? 10.488  53.941  13.811  1.00 29.89  ? 124 TYR A CZ  1 
ATOM   993   O OH  . TYR A 1 124 ? 9.636   53.314  12.945  1.00 30.14  ? 124 TYR A OH  1 
ATOM   994   N N   . VAL A 1 125 ? 14.145  52.660  16.892  1.00 26.10  ? 125 VAL A N   1 
ATOM   995   C CA  . VAL A 1 125 ? 13.953  51.354  17.489  1.00 27.30  ? 125 VAL A CA  1 
ATOM   996   C C   . VAL A 1 125 ? 15.046  51.085  18.518  1.00 28.86  ? 125 VAL A C   1 
ATOM   997   O O   . VAL A 1 125 ? 14.780  50.558  19.594  1.00 29.13  ? 125 VAL A O   1 
ATOM   998   C CB  . VAL A 1 125 ? 13.972  50.288  16.376  1.00 29.94  ? 125 VAL A CB  1 
ATOM   999   C CG1 . VAL A 1 125 ? 14.132  48.875  16.941  1.00 29.81  ? 125 VAL A CG1 1 
ATOM   1000  C CG2 . VAL A 1 125 ? 12.739  50.408  15.487  1.00 31.39  ? 125 VAL A CG2 1 
ATOM   1001  N N   . PHE A 1 126 ? 16.288  51.399  18.141  1.00 26.48  ? 126 PHE A N   1 
ATOM   1002  C CA  . PHE A 1 126 ? 17.409  51.270  19.041  1.00 27.55  ? 126 PHE A CA  1 
ATOM   1003  C C   . PHE A 1 126 ? 17.212  52.221  20.216  1.00 27.22  ? 126 PHE A C   1 
ATOM   1004  O O   . PHE A 1 126 ? 17.428  51.821  21.360  1.00 26.41  ? 126 PHE A O   1 
ATOM   1005  C CB  . PHE A 1 126 ? 18.703  51.461  18.246  1.00 30.04  ? 126 PHE A CB  1 
ATOM   1006  C CG  . PHE A 1 126 ? 18.962  50.383  17.196  1.00 29.90  ? 126 PHE A CG  1 
ATOM   1007  C CD1 . PHE A 1 126 ? 19.241  49.064  17.566  1.00 29.66  ? 126 PHE A CD1 1 
ATOM   1008  C CD2 . PHE A 1 126 ? 18.969  50.698  15.839  1.00 28.14  ? 126 PHE A CD2 1 
ATOM   1009  C CE1 . PHE A 1 126 ? 19.481  48.093  16.606  1.00 29.63  ? 126 PHE A CE1 1 
ATOM   1010  C CE2 . PHE A 1 126 ? 19.214  49.729  14.874  1.00 27.63  ? 126 PHE A CE2 1 
ATOM   1011  C CZ  . PHE A 1 126 ? 19.483  48.434  15.259  1.00 31.04  ? 126 PHE A CZ  1 
ATOM   1012  N N   . ASP A 1 127 ? 16.707  53.429  19.947  1.00 27.17  ? 127 ASP A N   1 
ATOM   1013  C CA  . ASP A 1 127 ? 16.428  54.375  21.023  1.00 28.28  ? 127 ASP A CA  1 
ATOM   1014  C C   . ASP A 1 127 ? 15.431  53.771  21.997  1.00 27.08  ? 127 ASP A C   1 
ATOM   1015  O O   . ASP A 1 127 ? 15.644  53.825  23.195  1.00 26.81  ? 127 ASP A O   1 
ATOM   1016  C CB  . ASP A 1 127 ? 15.975  55.729  20.500  1.00 30.46  ? 127 ASP A CB  1 
ATOM   1017  C CG  . ASP A 1 127 ? 16.995  56.421  19.604  1.00 31.18  ? 127 ASP A CG  1 
ATOM   1018  O OD1 . ASP A 1 127 ? 18.175  55.993  19.642  1.00 30.95  ? 127 ASP A OD1 1 
ATOM   1019  O OD2 . ASP A 1 127 ? 16.604  57.354  18.865  1.00 29.96  ? 127 ASP A OD2 1 
ATOM   1020  N N   . VAL A 1 128 ? 14.369  53.160  21.470  1.00 28.07  ? 128 VAL A N   1 
ATOM   1021  C CA  . VAL A 1 128 ? 13.384  52.475  22.297  1.00 28.07  ? 128 VAL A CA  1 
ATOM   1022  C C   . VAL A 1 128 ? 14.074  51.355  23.093  1.00 28.81  ? 128 VAL A C   1 
ATOM   1023  O O   . VAL A 1 128 ? 13.980  51.312  24.323  1.00 33.19  ? 128 VAL A O   1 
ATOM   1024  C CB  . VAL A 1 128 ? 12.165  51.987  21.463  1.00 27.60  ? 128 VAL A CB  1 
ATOM   1025  C CG1 . VAL A 1 128 ? 11.277  50.960  22.170  1.00 27.14  ? 128 VAL A CG1 1 
ATOM   1026  C CG2 . VAL A 1 128 ? 11.288  53.159  21.040  1.00 29.16  ? 128 VAL A CG2 1 
ATOM   1027  N N   . LEU A 1 129 ? 14.801  50.457  22.423  1.00 27.51  ? 129 LEU A N   1 
ATOM   1028  C CA  . LEU A 1 129 ? 15.454  49.372  23.142  1.00 27.54  ? 129 LEU A CA  1 
ATOM   1029  C C   . LEU A 1 129 ? 16.293  49.899  24.292  1.00 27.11  ? 129 LEU A C   1 
ATOM   1030  O O   . LEU A 1 129 ? 16.308  49.271  25.336  1.00 30.02  ? 129 LEU A O   1 
ATOM   1031  C CB  . LEU A 1 129 ? 16.315  48.510  22.238  1.00 26.93  ? 129 LEU A CB  1 
ATOM   1032  C CG  . LEU A 1 129 ? 15.524  47.716  21.211  1.00 27.59  ? 129 LEU A CG  1 
ATOM   1033  C CD1 . LEU A 1 129 ? 16.461  47.126  20.190  1.00 28.28  ? 129 LEU A CD1 1 
ATOM   1034  C CD2 . LEU A 1 129 ? 14.725  46.652  21.957  1.00 27.64  ? 129 LEU A CD2 1 
ATOM   1035  N N   . ARG A 1 130 ? 16.975  51.032  24.110  1.00 27.57  ? 130 ARG A N   1 
ATOM   1036  C CA  . ARG A 1 130 ? 17.879  51.521  25.142  1.00 27.82  ? 130 ARG A CA  1 
ATOM   1037  C C   . ARG A 1 130 ? 17.130  52.265  26.242  1.00 27.77  ? 130 ARG A C   1 
ATOM   1038  O O   . ARG A 1 130 ? 17.644  52.374  27.348  1.00 26.38  ? 130 ARG A O   1 
ATOM   1039  C CB  . ARG A 1 130 ? 18.976  52.447  24.617  1.00 27.25  ? 130 ARG A CB  1 
ATOM   1040  C CG  . ARG A 1 130 ? 20.105  51.708  23.926  1.00 29.97  ? 130 ARG A CG  1 
ATOM   1041  C CD  . ARG A 1 130 ? 21.260  52.656  23.552  1.00 33.60  ? 130 ARG A CD  1 
ATOM   1042  N NE  . ARG A 1 130 ? 22.285  52.837  24.585  1.00 30.67  ? 130 ARG A NE  1 
ATOM   1043  C CZ  . ARG A 1 130 ? 23.101  51.860  24.950  1.00 33.58  ? 130 ARG A CZ  1 
ATOM   1044  N NH1 . ARG A 1 130 ? 23.923  52.041  25.971  1.00 31.84  ? 130 ARG A NH1 1 
ATOM   1045  N NH2 . ARG A 1 130 ? 23.068  50.692  24.315  1.00 34.51  ? 130 ARG A NH2 1 
ATOM   1046  N N   . ALA A 1 131 ? 15.935  52.791  25.959  1.00 26.82  ? 131 ALA A N   1 
ATOM   1047  C CA  . ALA A 1 131 ? 15.192  53.504  26.995  1.00 27.66  ? 131 ALA A CA  1 
ATOM   1048  C C   . ALA A 1 131 ? 14.700  52.521  28.053  1.00 24.13  ? 131 ALA A C   1 
ATOM   1049  O O   . ALA A 1 131 ? 14.354  52.923  29.143  1.00 23.09  ? 131 ALA A O   1 
ATOM   1050  C CB  . ALA A 1 131 ? 14.037  54.305  26.407  1.00 26.40  ? 131 ALA A CB  1 
ATOM   1051  N N   . MET A 1 132 ? 14.641  51.238  27.706  1.00 23.37  ? 132 MET A N   1 
ATOM   1052  C CA  . MET A 1 132 ? 14.186  50.215  28.629  1.00 25.39  ? 132 MET A CA  1 
ATOM   1053  C C   . MET A 1 132 ? 15.339  49.856  29.562  1.00 29.24  ? 132 MET A C   1 
ATOM   1054  O O   . MET A 1 132 ? 16.479  49.742  29.118  1.00 29.61  ? 132 MET A O   1 
ATOM   1055  C CB  . MET A 1 132 ? 13.723  48.959  27.880  1.00 26.32  ? 132 MET A CB  1 
ATOM   1056  C CG  . MET A 1 132 ? 12.641  49.206  26.839  1.00 27.85  ? 132 MET A CG  1 
ATOM   1057  S SD  . MET A 1 132 ? 12.201  47.730  25.892  1.00 31.46  ? 132 MET A SD  1 
ATOM   1058  C CE  . MET A 1 132 ? 10.693  47.273  26.754  1.00 29.24  ? 132 MET A CE  1 
ATOM   1059  N N   . PRO A 1 133 ? 15.106  49.679  30.879  1.00 29.34  ? 133 PRO A N   1 
ATOM   1060  C CA  . PRO A 1 133 ? 16.193  49.347  31.791  1.00 28.19  ? 133 PRO A CA  1 
ATOM   1061  C C   . PRO A 1 133 ? 16.767  48.023  31.317  1.00 24.21  ? 133 PRO A C   1 
ATOM   1062  O O   . PRO A 1 133 ? 16.014  47.193  30.872  1.00 23.36  ? 133 PRO A O   1 
ATOM   1063  C CB  . PRO A 1 133 ? 15.512  49.232  33.154  1.00 29.30  ? 133 PRO A CB  1 
ATOM   1064  C CG  . PRO A 1 133 ? 14.225  50.023  32.992  1.00 30.88  ? 133 PRO A CG  1 
ATOM   1065  C CD  . PRO A 1 133 ? 13.806  49.787  31.550  1.00 31.19  ? 133 PRO A CD  1 
ATOM   1066  N N   . VAL A 1 134 ? 18.081  47.814  31.460  1.00 24.15  ? 134 VAL A N   1 
ATOM   1067  C CA  . VAL A 1 134 ? 18.728  46.654  30.870  1.00 25.45  ? 134 VAL A CA  1 
ATOM   1068  C C   . VAL A 1 134 ? 18.318  45.360  31.580  1.00 24.13  ? 134 VAL A C   1 
ATOM   1069  O O   . VAL A 1 134 ? 18.452  44.294  30.994  1.00 21.85  ? 134 VAL A O   1 
ATOM   1070  C CB  . VAL A 1 134 ? 20.259  46.801  30.814  1.00 27.01  ? 134 VAL A CB  1 
ATOM   1071  C CG1 . VAL A 1 134 ? 20.907  46.895  32.197  1.00 28.98  ? 134 VAL A CG1 1 
ATOM   1072  C CG2 . VAL A 1 134 ? 20.887  45.672  30.009  1.00 26.92  ? 134 VAL A CG2 1 
ATOM   1073  N N   . ASP A 1 135 ? 17.781  45.441  32.807  1.00 26.59  ? 135 ASP A N   1 
ATOM   1074  C CA  . ASP A 1 135 ? 17.280  44.270  33.531  1.00 28.27  ? 135 ASP A CA  1 
ATOM   1075  C C   . ASP A 1 135 ? 15.854  43.866  33.107  1.00 26.87  ? 135 ASP A C   1 
ATOM   1076  O O   . ASP A 1 135 ? 15.346  42.871  33.624  1.00 23.53  ? 135 ASP A O   1 
ATOM   1077  C CB  . ASP A 1 135 ? 17.428  44.421  35.045  1.00 28.09  ? 135 ASP A CB  1 
ATOM   1078  C CG  . ASP A 1 135 ? 16.573  45.494  35.711  1.00 28.84  ? 135 ASP A CG  1 
ATOM   1079  O OD1 . ASP A 1 135 ? 15.920  46.271  34.985  1.00 28.51  ? 135 ASP A OD1 1 
ATOM   1080  O OD2 . ASP A 1 135 ? 16.533  45.526  36.960  1.00 29.59  ? 135 ASP A OD2 1 
ATOM   1081  N N   . THR A 1 136 ? 15.251  44.563  32.121  1.00 26.69  ? 136 THR A N   1 
ATOM   1082  C CA  . THR A 1 136 ? 13.978  44.170  31.523  1.00 27.66  ? 136 THR A CA  1 
ATOM   1083  C C   . THR A 1 136 ? 14.108  42.791  30.863  1.00 30.20  ? 136 THR A C   1 
ATOM   1084  O O   . THR A 1 136 ? 15.119  42.494  30.225  1.00 30.93  ? 136 THR A O   1 
ATOM   1085  C CB  . THR A 1 136 ? 13.527  45.213  30.495  1.00 26.39  ? 136 THR A CB  1 
ATOM   1086  O OG1 . THR A 1 136 ? 13.213  46.471  31.083  1.00 24.25  ? 136 THR A OG1 1 
ATOM   1087  C CG2 . THR A 1 136 ? 12.233  44.814  29.815  1.00 27.69  ? 136 THR A CG2 1 
ATOM   1088  N N   . HIS A 1 137 ? 13.068  41.949  30.982  1.00 29.65  ? 137 HIS A N   1 
ATOM   1089  C CA  . HIS A 1 137 ? 13.087  40.617  30.388  1.00 30.67  ? 137 HIS A CA  1 
ATOM   1090  C C   . HIS A 1 137 ? 13.303  40.746  28.881  1.00 31.82  ? 137 HIS A C   1 
ATOM   1091  O O   . HIS A 1 137 ? 12.853  41.701  28.250  1.00 34.10  ? 137 HIS A O   1 
ATOM   1092  C CB  . HIS A 1 137 ? 11.787  39.853  30.673  1.00 32.34  ? 137 HIS A CB  1 
ATOM   1093  C CG  . HIS A 1 137 ? 11.809  38.410  30.281  1.00 32.27  ? 137 HIS A CG  1 
ATOM   1094  N ND1 . HIS A 1 137 ? 11.737  37.975  28.975  1.00 29.52  ? 137 HIS A ND1 1 
ATOM   1095  C CD2 . HIS A 1 137 ? 11.969  37.309  31.036  1.00 33.14  ? 137 HIS A CD2 1 
ATOM   1096  C CE1 . HIS A 1 137 ? 11.820  36.659  28.947  1.00 30.20  ? 137 HIS A CE1 1 
ATOM   1097  N NE2 . HIS A 1 137 ? 11.989  36.234  30.189  1.00 33.03  ? 137 HIS A NE2 1 
ATOM   1098  N N   . PRO A 1 138 ? 14.036  39.821  28.244  1.00 32.20  ? 138 PRO A N   1 
ATOM   1099  C CA  . PRO A 1 138 ? 14.325  39.981  26.816  1.00 31.57  ? 138 PRO A CA  1 
ATOM   1100  C C   . PRO A 1 138 ? 13.136  39.922  25.855  1.00 28.57  ? 138 PRO A C   1 
ATOM   1101  O O   . PRO A 1 138 ? 13.095  40.647  24.855  1.00 26.91  ? 138 PRO A O   1 
ATOM   1102  C CB  . PRO A 1 138 ? 15.425  38.939  26.517  1.00 33.42  ? 138 PRO A CB  1 
ATOM   1103  C CG  . PRO A 1 138 ? 15.449  38.011  27.721  1.00 36.28  ? 138 PRO A CG  1 
ATOM   1104  C CD  . PRO A 1 138 ? 14.771  38.727  28.894  1.00 33.64  ? 138 PRO A CD  1 
ATOM   1105  N N   . MET A 1 139 ? 12.139  39.097  26.173  1.00 31.32  ? 139 MET A N   1 
ATOM   1106  C CA  . MET A 1 139 ? 10.908  39.034  25.389  1.00 28.35  ? 139 MET A CA  1 
ATOM   1107  C C   . MET A 1 139 ? 10.071  40.323  25.490  1.00 27.32  ? 139 MET A C   1 
ATOM   1108  O O   . MET A 1 139 ? 9.366   40.695  24.546  1.00 27.34  ? 139 MET A O   1 
ATOM   1109  C CB  . MET A 1 139 ? 10.083  37.826  25.817  1.00 29.65  ? 139 MET A CB  1 
ATOM   1110  C CG  . MET A 1 139 ? 10.667  36.517  25.344  1.00 30.72  ? 139 MET A CG  1 
ATOM   1111  S SD  . MET A 1 139 ? 10.561  36.352  23.549  1.00 30.74  ? 139 MET A SD  1 
ATOM   1112  C CE  . MET A 1 139 ? 8.833   36.158  23.107  1.00 28.73  ? 139 MET A CE  1 
ATOM   1113  N N   . THR A 1 140 ? 10.152  41.049  26.603  1.00 25.58  ? 140 THR A N   1 
ATOM   1114  C CA  . THR A 1 140 ? 9.523   42.370  26.671  1.00 26.28  ? 140 THR A CA  1 
ATOM   1115  C C   . THR A 1 140 ? 10.261  43.343  25.752  1.00 26.74  ? 140 THR A C   1 
ATOM   1116  O O   . THR A 1 140 ? 9.626   44.054  24.991  1.00 25.53  ? 140 THR A O   1 
ATOM   1117  C CB  . THR A 1 140 ? 9.480   42.887  28.108  1.00 24.77  ? 140 THR A CB  1 
ATOM   1118  O OG1 . THR A 1 140 ? 8.739   41.912  28.832  1.00 24.35  ? 140 THR A OG1 1 
ATOM   1119  C CG2 . THR A 1 140 ? 8.783   44.227  28.250  1.00 24.71  ? 140 THR A CG2 1 
ATOM   1120  N N   . MET A 1 141 ? 11.600  43.363  25.830  1.00 28.49  ? 141 MET A N   1 
ATOM   1121  C CA  . MET A 1 141 ? 12.427  44.177  24.955  1.00 27.79  ? 141 MET A CA  1 
ATOM   1122  C C   . MET A 1 141 ? 12.159  43.822  23.493  1.00 27.07  ? 141 MET A C   1 
ATOM   1123  O O   . MET A 1 141 ? 11.909  44.695  22.667  1.00 26.40  ? 141 MET A O   1 
ATOM   1124  C CB  . MET A 1 141 ? 13.918  43.931  25.210  1.00 30.41  ? 141 MET A CB  1 
ATOM   1125  C CG  . MET A 1 141 ? 14.491  44.634  26.430  1.00 31.75  ? 141 MET A CG  1 
ATOM   1126  S SD  . MET A 1 141 ? 16.239  44.218  26.618  1.00 28.86  ? 141 MET A SD  1 
ATOM   1127  C CE  . MET A 1 141 ? 16.608  45.141  28.112  1.00 30.41  ? 141 MET A CE  1 
ATOM   1128  N N   . PHE A 1 142 ? 12.226  42.531  23.172  1.00 25.83  ? 142 PHE A N   1 
ATOM   1129  C CA  . PHE A 1 142 ? 12.007  42.097  21.804  1.00 25.62  ? 142 PHE A CA  1 
ATOM   1130  C C   . PHE A 1 142 ? 10.665  42.590  21.252  1.00 25.98  ? 142 PHE A C   1 
ATOM   1131  O O   . PHE A 1 142 ? 10.597  43.256  20.219  1.00 23.80  ? 142 PHE A O   1 
ATOM   1132  C CB  . PHE A 1 142 ? 12.078  40.570  21.812  1.00 25.34  ? 142 PHE A CB  1 
ATOM   1133  C CG  . PHE A 1 142 ? 12.132  39.916  20.432  1.00 24.93  ? 142 PHE A CG  1 
ATOM   1134  C CD1 . PHE A 1 142 ? 13.022  40.361  19.466  1.00 22.76  ? 142 PHE A CD1 1 
ATOM   1135  C CD2 . PHE A 1 142 ? 11.288  38.865  20.109  1.00 24.71  ? 142 PHE A CD2 1 
ATOM   1136  C CE1 . PHE A 1 142 ? 13.101  39.738  18.245  1.00 23.00  ? 142 PHE A CE1 1 
ATOM   1137  C CE2 . PHE A 1 142 ? 11.373  38.248  18.877  1.00 24.96  ? 142 PHE A CE2 1 
ATOM   1138  C CZ  . PHE A 1 142 ? 12.268  38.699  17.943  1.00 23.49  ? 142 PHE A CZ  1 
ATOM   1139  N N   . ALA A 1 143 ? 9.572   42.227  21.932  1.00 28.21  ? 143 ALA A N   1 
ATOM   1140  C CA  . ALA A 1 143 ? 8.234   42.603  21.496  1.00 26.83  ? 143 ALA A CA  1 
ATOM   1141  C C   . ALA A 1 143 ? 8.108   44.124  21.381  1.00 25.73  ? 143 ALA A C   1 
ATOM   1142  O O   . ALA A 1 143 ? 7.521   44.599  20.418  1.00 27.35  ? 143 ALA A O   1 
ATOM   1143  C CB  . ALA A 1 143 ? 7.196   42.023  22.437  1.00 27.20  ? 143 ALA A CB  1 
ATOM   1144  N N   . ALA A 1 144 ? 8.704   44.889  22.312  1.00 25.46  ? 144 ALA A N   1 
ATOM   1145  C CA  . ALA A 1 144 ? 8.579   46.346  22.297  1.00 25.99  ? 144 ALA A CA  1 
ATOM   1146  C C   . ALA A 1 144 ? 9.315   46.950  21.098  1.00 25.53  ? 144 ALA A C   1 
ATOM   1147  O O   . ALA A 1 144 ? 8.899   47.965  20.528  1.00 24.75  ? 144 ALA A O   1 
ATOM   1148  C CB  . ALA A 1 144 ? 9.070   46.956  23.609  1.00 24.16  ? 144 ALA A CB  1 
ATOM   1149  N N   . GLY A 1 145 ? 10.442  46.339  20.736  1.00 24.05  ? 145 GLY A N   1 
ATOM   1150  C CA  . GLY A 1 145 ? 11.213  46.826  19.613  1.00 24.97  ? 145 GLY A CA  1 
ATOM   1151  C C   . GLY A 1 145 ? 10.485  46.622  18.288  1.00 24.04  ? 145 GLY A C   1 
ATOM   1152  O O   . GLY A 1 145 ? 10.461  47.504  17.431  1.00 22.11  ? 145 GLY A O   1 
ATOM   1153  N N   . ILE A 1 146 ? 9.913   45.430  18.136  1.00 26.38  ? 146 ILE A N   1 
ATOM   1154  C CA  . ILE A 1 146 ? 9.099   45.106  16.977  1.00 26.33  ? 146 ILE A CA  1 
ATOM   1155  C C   . ILE A 1 146 ? 7.933   46.082  16.874  1.00 27.79  ? 146 ILE A C   1 
ATOM   1156  O O   . ILE A 1 146 ? 7.652   46.626  15.803  1.00 29.28  ? 146 ILE A O   1 
ATOM   1157  C CB  . ILE A 1 146 ? 8.573   43.676  17.083  1.00 24.44  ? 146 ILE A CB  1 
ATOM   1158  C CG1 . ILE A 1 146 ? 9.742   42.684  17.120  1.00 22.56  ? 146 ILE A CG1 1 
ATOM   1159  C CG2 . ILE A 1 146 ? 7.592   43.432  15.940  1.00 24.61  ? 146 ILE A CG2 1 
ATOM   1160  C CD1 . ILE A 1 146 ? 9.339   41.258  17.388  1.00 22.05  ? 146 ILE A CD1 1 
ATOM   1161  N N   . LEU A 1 147 ? 7.252   46.282  18.005  1.00 28.88  ? 147 LEU A N   1 
ATOM   1162  C CA  . LEU A 1 147 ? 6.068   47.129  18.051  1.00 28.26  ? 147 LEU A CA  1 
ATOM   1163  C C   . LEU A 1 147 ? 6.426   48.554  17.624  1.00 28.17  ? 147 LEU A C   1 
ATOM   1164  O O   . LEU A 1 147 ? 5.643   49.150  16.889  1.00 30.22  ? 147 LEU A O   1 
ATOM   1165  C CB  . LEU A 1 147 ? 5.358   47.083  19.403  1.00 25.68  ? 147 LEU A CB  1 
ATOM   1166  C CG  . LEU A 1 147 ? 4.150   48.012  19.570  1.00 27.74  ? 147 LEU A CG  1 
ATOM   1167  C CD1 . LEU A 1 147 ? 3.056   47.748  18.556  1.00 26.56  ? 147 LEU A CD1 1 
ATOM   1168  C CD2 . LEU A 1 147 ? 3.639   47.831  20.994  1.00 28.64  ? 147 LEU A CD2 1 
ATOM   1169  N N   . ALA A 1 148 ? 7.587   49.089  18.040  1.00 26.18  ? 148 ALA A N   1 
ATOM   1170  C CA  . ALA A 1 148 ? 7.904   50.482  17.723  1.00 29.22  ? 148 ALA A CA  1 
ATOM   1171  C C   . ALA A 1 148 ? 8.048   50.665  16.220  1.00 26.62  ? 148 ALA A C   1 
ATOM   1172  O O   . ALA A 1 148 ? 7.742   51.723  15.712  1.00 25.95  ? 148 ALA A O   1 
ATOM   1173  C CB  . ALA A 1 148 ? 9.151   50.984  18.441  1.00 31.48  ? 148 ALA A CB  1 
ATOM   1174  N N   . MET A 1 149 ? 8.511   49.618  15.528  1.00 29.19  ? 149 MET A N   1 
ATOM   1175  C CA  . MET A 1 149 ? 8.743   49.648  14.088  1.00 28.81  ? 149 MET A CA  1 
ATOM   1176  C C   . MET A 1 149 ? 7.432   49.672  13.280  1.00 28.79  ? 149 MET A C   1 
ATOM   1177  O O   . MET A 1 149 ? 7.435   49.933  12.080  1.00 28.53  ? 149 MET A O   1 
ATOM   1178  C CB  . MET A 1 149 ? 9.627   48.455  13.719  1.00 27.08  ? 149 MET A CB  1 
ATOM   1179  C CG  . MET A 1 149 ? 10.262  48.552  12.372  1.00 28.67  ? 149 MET A CG  1 
ATOM   1180  S SD  . MET A 1 149 ? 11.597  47.355  12.142  1.00 31.14  ? 149 MET A SD  1 
ATOM   1181  C CE  . MET A 1 149 ? 11.763  47.410  10.350  1.00 29.32  ? 149 MET A CE  1 
ATOM   1182  N N   . GLN A 1 150 ? 6.295   49.445  13.942  1.00 26.21  ? 150 GLN A N   1 
ATOM   1183  C CA  . GLN A 1 150 ? 4.991   49.625  13.322  1.00 28.49  ? 150 GLN A CA  1 
ATOM   1184  C C   . GLN A 1 150 ? 4.911   50.901  12.481  1.00 28.66  ? 150 GLN A C   1 
ATOM   1185  O O   . GLN A 1 150 ? 4.123   50.956  11.531  1.00 24.59  ? 150 GLN A O   1 
ATOM   1186  C CB  . GLN A 1 150 ? 3.905   49.717  14.394  1.00 28.19  ? 150 GLN A CB  1 
ATOM   1187  C CG  . GLN A 1 150 ? 2.473   49.602  13.892  1.00 28.71  ? 150 GLN A CG  1 
ATOM   1188  C CD  . GLN A 1 150 ? 1.869   50.903  13.399  1.00 30.02  ? 150 GLN A CD  1 
ATOM   1189  O OE1 . GLN A 1 150 ? 1.114   50.917  12.409  1.00 29.10  ? 150 GLN A OE1 1 
ATOM   1190  N NE2 . GLN A 1 150 ? 2.141   51.988  14.114  1.00 25.92  ? 150 GLN A NE2 1 
ATOM   1191  N N   . ARG A 1 151 ? 5.682   51.931  12.849  1.00 25.69  ? 151 ARG A N   1 
ATOM   1192  C CA  . ARG A 1 151 ? 5.568   53.208  12.174  1.00 24.69  ? 151 ARG A CA  1 
ATOM   1193  C C   . ARG A 1 151 ? 5.874   53.027  10.695  1.00 25.35  ? 151 ARG A C   1 
ATOM   1194  O O   . ARG A 1 151 ? 5.392   53.793  9.889   1.00 28.77  ? 151 ARG A O   1 
ATOM   1195  C CB  . ARG A 1 151 ? 6.526   54.242  12.756  1.00 23.51  ? 151 ARG A CB  1 
ATOM   1196  C CG  . ARG A 1 151 ? 6.511   55.626  12.132  1.00 23.39  ? 151 ARG A CG  1 
ATOM   1197  C CD  . ARG A 1 151 ? 7.657   56.440  12.767  1.00 26.39  ? 151 ARG A CD  1 
ATOM   1198  N NE  . ARG A 1 151 ? 7.792   57.798  12.227  1.00 26.24  ? 151 ARG A NE  1 
ATOM   1199  C CZ  . ARG A 1 151 ? 8.566   58.156  11.200  1.00 26.13  ? 151 ARG A CZ  1 
ATOM   1200  N NH1 . ARG A 1 151 ? 9.307   57.266  10.541  1.00 27.25  ? 151 ARG A NH1 1 
ATOM   1201  N NH2 . ARG A 1 151 ? 8.576   59.425  10.837  1.00 24.01  ? 151 ARG A NH2 1 
ATOM   1202  N N   . GLU A 1 152 ? 6.692   52.033  10.352  1.00 28.06  ? 152 GLU A N   1 
ATOM   1203  C CA  . GLU A 1 152 ? 7.122   51.802  8.981   1.00 29.57  ? 152 GLU A CA  1 
ATOM   1204  C C   . GLU A 1 152 ? 6.203   50.787  8.289   1.00 30.76  ? 152 GLU A C   1 
ATOM   1205  O O   . GLU A 1 152 ? 6.622   50.151  7.322   1.00 29.91  ? 152 GLU A O   1 
ATOM   1206  C CB  . GLU A 1 152 ? 8.568   51.272  9.016   1.00 31.38  ? 152 GLU A CB  1 
ATOM   1207  C CG  . GLU A 1 152 ? 9.576   52.169  9.746   1.00 30.54  ? 152 GLU A CG  1 
ATOM   1208  C CD  . GLU A 1 152 ? 9.481   53.665  9.467   1.00 29.84  ? 152 GLU A CD  1 
ATOM   1209  O OE1 . GLU A 1 152 ? 9.494   54.418  10.480  1.00 25.80  ? 152 GLU A OE1 1 
ATOM   1210  O OE2 . GLU A 1 152 ? 9.350   54.077  8.272   1.00 26.00  ? 152 GLU A OE2 1 
ATOM   1211  N N   . SER A 1 153 ? 4.979   50.569  8.807   1.00 30.20  ? 153 SER A N   1 
ATOM   1212  C CA  . SER A 1 153 ? 4.135   49.537  8.239   1.00 32.41  ? 153 SER A CA  1 
ATOM   1213  C C   . SER A 1 153 ? 3.559   50.025  6.923   1.00 32.43  ? 153 SER A C   1 
ATOM   1214  O O   . SER A 1 153 ? 2.868   51.031  6.887   1.00 29.59  ? 153 SER A O   1 
ATOM   1215  C CB  . SER A 1 153 ? 3.013   49.084  9.095   1.00 33.70  ? 153 SER A CB  1 
ATOM   1216  O OG  . SER A 1 153 ? 2.329   48.058  8.380   1.00 31.46  ? 153 SER A OG  1 
ATOM   1217  N N   . VAL A 1 154 ? 3.882   49.281  5.869   1.00 32.39  ? 154 VAL A N   1 
ATOM   1218  C CA  . VAL A 1 154 ? 3.369   49.542  4.541   1.00 34.32  ? 154 VAL A CA  1 
ATOM   1219  C C   . VAL A 1 154 ? 1.877   49.238  4.520   1.00 32.29  ? 154 VAL A C   1 
ATOM   1220  O O   . VAL A 1 154 ? 1.083   50.008  3.963   1.00 30.68  ? 154 VAL A O   1 
ATOM   1221  C CB  . VAL A 1 154 ? 4.130   48.682  3.522   1.00 33.18  ? 154 VAL A CB  1 
ATOM   1222  C CG1 . VAL A 1 154 ? 3.551   48.876  2.138   1.00 34.97  ? 154 VAL A CG1 1 
ATOM   1223  C CG2 . VAL A 1 154 ? 5.622   48.983  3.535   1.00 32.23  ? 154 VAL A CG2 1 
ATOM   1224  N N   . PHE A 1 155 ? 1.518   48.117  5.157   1.00 31.75  ? 155 PHE A N   1 
ATOM   1225  C CA  . PHE A 1 155 ? 0.127   47.697  5.213   1.00 33.50  ? 155 PHE A CA  1 
ATOM   1226  C C   . PHE A 1 155 ? -0.699  48.790  5.887   1.00 35.60  ? 155 PHE A C   1 
ATOM   1227  O O   . PHE A 1 155 ? -1.770  49.112  5.388   1.00 37.67  ? 155 PHE A O   1 
ATOM   1228  C CB  . PHE A 1 155 ? -0.079  46.350  5.911   1.00 31.92  ? 155 PHE A CB  1 
ATOM   1229  C CG  . PHE A 1 155 ? -1.519  45.858  5.917   1.00 33.27  ? 155 PHE A CG  1 
ATOM   1230  C CD1 . PHE A 1 155 ? -2.448  46.373  6.811   1.00 35.73  ? 155 PHE A CD1 1 
ATOM   1231  C CD2 . PHE A 1 155 ? -1.936  44.873  5.036   1.00 36.01  ? 155 PHE A CD2 1 
ATOM   1232  C CE1 . PHE A 1 155 ? -3.757  45.924  6.811   1.00 37.31  ? 155 PHE A CE1 1 
ATOM   1233  C CE2 . PHE A 1 155 ? -3.240  44.419  5.051   1.00 36.87  ? 155 PHE A CE2 1 
ATOM   1234  C CZ  . PHE A 1 155 ? -4.149  44.949  5.930   1.00 35.71  ? 155 PHE A CZ  1 
ATOM   1235  N N   . ALA A 1 156 ? -0.223  49.352  7.011   1.00 33.56  ? 156 ALA A N   1 
ATOM   1236  C CA  . ALA A 1 156 ? -1.057  50.311  7.711   1.00 34.65  ? 156 ALA A CA  1 
ATOM   1237  C C   . ALA A 1 156 ? -1.223  51.548  6.848   1.00 36.06  ? 156 ALA A C   1 
ATOM   1238  O O   . ALA A 1 156 ? -2.338  52.038  6.712   1.00 36.89  ? 156 ALA A O   1 
ATOM   1239  C CB  . ALA A 1 156 ? -0.542  50.662  9.076   1.00 34.48  ? 156 ALA A CB  1 
ATOM   1240  N N   . LYS A 1 157 ? -0.119  52.034  6.273   1.00 40.96  ? 157 LYS A N   1 
ATOM   1241  C CA  . LYS A 1 157 ? -0.154  53.234  5.445   1.00 46.61  ? 157 LYS A CA  1 
ATOM   1242  C C   . LYS A 1 157 ? -1.045  53.014  4.218   1.00 43.60  ? 157 LYS A C   1 
ATOM   1243  O O   . LYS A 1 157 ? -1.935  53.817  3.982   1.00 47.30  ? 157 LYS A O   1 
ATOM   1244  C CB  . LYS A 1 157 ? 1.256   53.704  5.061   1.00 50.78  ? 157 LYS A CB  1 
ATOM   1245  C CG  . LYS A 1 157 ? 1.299   55.055  4.359   1.00 60.65  ? 157 LYS A CG  1 
ATOM   1246  C CD  . LYS A 1 157 ? 2.675   55.709  4.355   1.00 71.75  ? 157 LYS A CD  1 
ATOM   1247  C CE  . LYS A 1 157 ? 2.700   57.135  3.874   1.00 76.89  ? 157 LYS A CE  1 
ATOM   1248  N NZ  . LYS A 1 157 ? 3.671   57.927  4.644   1.00 79.22  ? 157 LYS A NZ  1 
ATOM   1249  N N   . ARG A 1 158 ? -0.823  51.932  3.456   1.00 44.76  ? 158 ARG A N   1 
ATOM   1250  C CA  . ARG A 1 158 ? -1.585  51.679  2.240   1.00 44.83  ? 158 ARG A CA  1 
ATOM   1251  C C   . ARG A 1 158 ? -3.073  51.571  2.587   1.00 45.03  ? 158 ARG A C   1 
ATOM   1252  O O   . ARG A 1 158 ? -3.921  52.138  1.905   1.00 54.14  ? 158 ARG A O   1 
ATOM   1253  C CB  . ARG A 1 158 ? -0.994  50.522  1.410   1.00 50.84  ? 158 ARG A CB  1 
ATOM   1254  C CG  . ARG A 1 158 ? -0.216  50.966  0.168   1.00 61.88  ? 158 ARG A CG  1 
ATOM   1255  C CD  . ARG A 1 158 ? 1.134   50.257  -0.160  1.00 71.87  ? 158 ARG A CD  1 
ATOM   1256  N NE  . ARG A 1 158 ? 1.172   48.985  -0.913  1.00 80.61  ? 158 ARG A NE  1 
ATOM   1257  C CZ  . ARG A 1 158 ? 2.270   48.281  -1.306  1.00 76.61  ? 158 ARG A CZ  1 
ATOM   1258  N NH1 . ARG A 1 158 ? 2.140   47.057  -1.815  1.00 68.79  ? 158 ARG A NH1 1 
ATOM   1259  N NH2 . ARG A 1 158 ? 3.495   48.776  -1.155  1.00 71.95  ? 158 ARG A NH2 1 
ATOM   1260  N N   . TYR A 1 159 ? -3.408  50.874  3.667   1.00 43.35  ? 159 TYR A N   1 
ATOM   1261  C CA  . TYR A 1 159 ? -4.789  50.762  4.101   1.00 41.88  ? 159 TYR A CA  1 
ATOM   1262  C C   . TYR A 1 159 ? -5.403  52.130  4.357   1.00 43.16  ? 159 TYR A C   1 
ATOM   1263  O O   . TYR A 1 159 ? -6.543  52.362  3.984   1.00 51.12  ? 159 TYR A O   1 
ATOM   1264  C CB  . TYR A 1 159 ? -4.966  50.001  5.414   1.00 42.75  ? 159 TYR A CB  1 
ATOM   1265  C CG  . TYR A 1 159 ? -6.424  49.676  5.679   1.00 48.24  ? 159 TYR A CG  1 
ATOM   1266  C CD1 . TYR A 1 159 ? -7.048  48.640  4.994   1.00 52.30  ? 159 TYR A CD1 1 
ATOM   1267  C CD2 . TYR A 1 159 ? -7.186  50.434  6.565   1.00 55.05  ? 159 TYR A CD2 1 
ATOM   1268  C CE1 . TYR A 1 159 ? -8.383  48.343  5.204   1.00 55.73  ? 159 TYR A CE1 1 
ATOM   1269  C CE2 . TYR A 1 159 ? -8.527  50.151  6.776   1.00 57.25  ? 159 TYR A CE2 1 
ATOM   1270  C CZ  . TYR A 1 159 ? -9.120  49.096  6.100   1.00 52.22  ? 159 TYR A CZ  1 
ATOM   1271  O OH  . TYR A 1 159 ? -10.432 48.800  6.279   1.00 52.87  ? 159 TYR A OH  1 
ATOM   1272  N N   . GLU A 1 160 ? -4.675  52.992  5.059   1.00 43.25  ? 160 GLU A N   1 
ATOM   1273  C CA  . GLU A 1 160 ? -5.168  54.306  5.441   1.00 50.73  ? 160 GLU A CA  1 
ATOM   1274  C C   . GLU A 1 160 ? -5.402  55.162  4.186   1.00 49.45  ? 160 GLU A C   1 
ATOM   1275  O O   . GLU A 1 160 ? -6.384  55.890  4.100   1.00 48.82  ? 160 GLU A O   1 
ATOM   1276  C CB  . GLU A 1 160 ? -4.174  54.898  6.446   1.00 55.05  ? 160 GLU A CB  1 
ATOM   1277  C CG  . GLU A 1 160 ? -4.778  55.871  7.458   1.00 61.41  ? 160 GLU A CG  1 
ATOM   1278  C CD  . GLU A 1 160 ? -5.112  57.241  6.897   1.00 74.46  ? 160 GLU A CD  1 
ATOM   1279  O OE1 . GLU A 1 160 ? -6.167  57.792  7.276   1.00 68.08  ? 160 GLU A OE1 1 
ATOM   1280  O OE2 . GLU A 1 160 ? -4.326  57.755  6.063   1.00 92.08  ? 160 GLU A OE2 1 
ATOM   1281  N N   . GLU A 1 161 ? -4.508  55.075  3.198   1.00 48.08  ? 161 GLU A N   1 
ATOM   1282  C CA  . GLU A 1 161 ? -4.670  55.796  1.941   1.00 51.66  ? 161 GLU A CA  1 
ATOM   1283  C C   . GLU A 1 161 ? -5.929  55.319  1.212   1.00 52.62  ? 161 GLU A C   1 
ATOM   1284  O O   . GLU A 1 161 ? -6.673  56.121  0.643   1.00 59.01  ? 161 GLU A O   1 
ATOM   1285  C CB  . GLU A 1 161 ? -3.456  55.547  1.037   1.00 54.49  ? 161 GLU A CB  1 
ATOM   1286  C CG  . GLU A 1 161 ? -2.177  56.229  1.512   1.00 55.17  ? 161 GLU A CG  1 
ATOM   1287  C CD  . GLU A 1 161 ? -0.890  55.900  0.773   1.00 56.64  ? 161 GLU A CD  1 
ATOM   1288  O OE1 . GLU A 1 161 ? 0.049   56.647  1.099   1.00 58.82  ? 161 GLU A OE1 1 
ATOM   1289  O OE2 . GLU A 1 161 ? -0.772  54.958  -0.055  1.00 55.55  ? 161 GLU A OE2 1 
ATOM   1290  N N   . GLY A 1 162 ? -6.147  53.999  1.259   1.00 46.52  ? 162 GLY A N   1 
ATOM   1291  C CA  . GLY A 1 162 ? -7.224  53.317  0.575   1.00 43.27  ? 162 GLY A CA  1 
ATOM   1292  C C   . GLY A 1 162 ? -6.606  52.368  -0.431  1.00 45.38  ? 162 GLY A C   1 
ATOM   1293  O O   . GLY A 1 162 ? -5.885  52.824  -1.299  1.00 54.57  ? 162 GLY A O   1 
ATOM   1294  N N   . MET A 1 163 ? -6.779  51.065  -0.241  1.00 43.97  ? 163 MET A N   1 
ATOM   1295  C CA  . MET A 1 163 ? -6.210  50.103  -1.173  1.00 45.75  ? 163 MET A CA  1 
ATOM   1296  C C   . MET A 1 163 ? -7.234  48.985  -1.347  1.00 47.89  ? 163 MET A C   1 
ATOM   1297  O O   . MET A 1 163 ? -8.019  48.717  -0.444  1.00 47.22  ? 163 MET A O   1 
ATOM   1298  C CB  . MET A 1 163 ? -4.826  49.566  -0.730  1.00 46.79  ? 163 MET A CB  1 
ATOM   1299  C CG  . MET A 1 163 ? -4.760  48.659  0.548   1.00 44.69  ? 163 MET A CG  1 
ATOM   1300  S SD  . MET A 1 163 ? -3.431  47.424  0.704   1.00 39.69  ? 163 MET A SD  1 
ATOM   1301  C CE  . MET A 1 163 ? -3.412  47.244  2.492   1.00 34.75  ? 163 MET A CE  1 
ATOM   1302  N N   . ARG A 1 164 ? -7.213  48.331  -2.506  1.00 54.64  ? 164 ARG A N   1 
ATOM   1303  C CA  . ARG A 1 164 ? -8.124  47.230  -2.784  1.00 64.99  ? 164 ARG A CA  1 
ATOM   1304  C C   . ARG A 1 164 ? -7.721  46.044  -1.916  1.00 56.87  ? 164 ARG A C   1 
ATOM   1305  O O   . ARG A 1 164 ? -6.559  45.925  -1.552  1.00 63.18  ? 164 ARG A O   1 
ATOM   1306  C CB  . ARG A 1 164 ? -8.105  46.864  -4.277  1.00 76.22  ? 164 ARG A CB  1 
ATOM   1307  C CG  . ARG A 1 164 ? -8.567  47.988  -5.198  1.00 84.03  ? 164 ARG A CG  1 
ATOM   1308  C CD  . ARG A 1 164 ? -8.390  47.725  -6.692  1.00 91.56  ? 164 ARG A CD  1 
ATOM   1309  N NE  . ARG A 1 164 ? -8.672  48.952  -7.452  1.00 101.53 ? 164 ARG A NE  1 
ATOM   1310  C CZ  . ARG A 1 164 ? -9.011  49.040  -8.741  1.00 97.53  ? 164 ARG A CZ  1 
ATOM   1311  N NH1 . ARG A 1 164 ? -9.155  47.950  -9.475  1.00 98.55  ? 164 ARG A NH1 1 
ATOM   1312  N NH2 . ARG A 1 164 ? -9.221  50.224  -9.290  1.00 85.02  ? 164 ARG A NH2 1 
ATOM   1313  N N   . ARG A 1 165 ? -8.678  45.168  -1.600  1.00 62.13  ? 165 ARG A N   1 
ATOM   1314  C CA  . ARG A 1 165 ? -8.419  44.034  -0.723  1.00 64.86  ? 165 ARG A CA  1 
ATOM   1315  C C   . ARG A 1 165 ? -7.423  43.068  -1.387  1.00 59.55  ? 165 ARG A C   1 
ATOM   1316  O O   . ARG A 1 165 ? -6.694  42.359  -0.696  1.00 51.65  ? 165 ARG A O   1 
ATOM   1317  C CB  . ARG A 1 165 ? -9.787  43.510  -0.259  1.00 67.30  ? 165 ARG A CB  1 
ATOM   1318  C CG  . ARG A 1 165 ? -10.513 44.506  0.641   1.00 75.53  ? 165 ARG A CG  1 
ATOM   1319  C CD  . ARG A 1 165 ? -12.003 44.254  0.820   1.00 83.00  ? 165 ARG A CD  1 
ATOM   1320  N NE  . ARG A 1 165 ? -12.263 42.935  1.416   1.00 87.98  ? 165 ARG A NE  1 
ATOM   1321  C CZ  . ARG A 1 165 ? -12.917 41.913  0.845   1.00 81.64  ? 165 ARG A CZ  1 
ATOM   1322  N NH1 . ARG A 1 165 ? -13.407 42.007  -0.383  1.00 74.92  ? 165 ARG A NH1 1 
ATOM   1323  N NH2 . ARG A 1 165 ? -13.081 40.783  1.516   1.00 74.39  ? 165 ARG A NH2 1 
ATOM   1324  N N   . GLU A 1 166 ? -7.345  43.107  -2.725  1.00 59.65  ? 166 GLU A N   1 
ATOM   1325  C CA  . GLU A 1 166 ? -6.445  42.288  -3.533  1.00 63.02  ? 166 GLU A CA  1 
ATOM   1326  C C   . GLU A 1 166 ? -4.966  42.677  -3.358  1.00 60.28  ? 166 GLU A C   1 
ATOM   1327  O O   . GLU A 1 166 ? -4.052  41.933  -3.743  1.00 49.08  ? 166 GLU A O   1 
ATOM   1328  C CB  . GLU A 1 166 ? -7.020  42.426  -4.947  1.00 67.06  ? 166 GLU A CB  1 
ATOM   1329  C CG  . GLU A 1 166 ? -6.000  42.403  -6.080  1.00 76.35  ? 166 GLU A CG  1 
ATOM   1330  C CD  . GLU A 1 166 ? -6.602  42.734  -7.441  1.00 83.56  ? 166 GLU A CD  1 
ATOM   1331  O OE1 . GLU A 1 166 ? -7.189  43.838  -7.602  1.00 88.53  ? 166 GLU A OE1 1 
ATOM   1332  O OE2 . GLU A 1 166 ? -6.476  41.877  -8.345  1.00 74.05  ? 166 GLU A OE2 1 
ATOM   1333  N N   . GLU A 1 167 ? -4.720  43.860  -2.785  1.00 56.06  ? 167 GLU A N   1 
ATOM   1334  C CA  . GLU A 1 167 ? -3.367  44.333  -2.550  1.00 61.22  ? 167 GLU A CA  1 
ATOM   1335  C C   . GLU A 1 167 ? -2.885  43.950  -1.148  1.00 50.99  ? 167 GLU A C   1 
ATOM   1336  O O   . GLU A 1 167 ? -1.702  44.114  -0.852  1.00 54.26  ? 167 GLU A O   1 
ATOM   1337  C CB  . GLU A 1 167 ? -3.285  45.846  -2.744  1.00 69.30  ? 167 GLU A CB  1 
ATOM   1338  C CG  . GLU A 1 167 ? -3.529  46.286  -4.184  1.00 78.01  ? 167 GLU A CG  1 
ATOM   1339  C CD  . GLU A 1 167 ? -3.720  47.789  -4.273  1.00 86.56  ? 167 GLU A CD  1 
ATOM   1340  O OE1 . GLU A 1 167 ? -2.841  48.503  -3.737  1.00 91.95  ? 167 GLU A OE1 1 
ATOM   1341  O OE2 . GLU A 1 167 ? -4.742  48.242  -4.840  1.00 78.57  ? 167 GLU A OE2 1 
ATOM   1342  N N   . HIS A 1 168 ? -3.772  43.384  -0.323  1.00 41.71  ? 168 HIS A N   1 
ATOM   1343  C CA  . HIS A 1 168 ? -3.472  43.125  1.079   1.00 41.55  ? 168 HIS A CA  1 
ATOM   1344  C C   . HIS A 1 168 ? -2.247  42.225  1.213   1.00 37.45  ? 168 HIS A C   1 
ATOM   1345  O O   . HIS A 1 168 ? -1.312  42.563  1.937   1.00 33.94  ? 168 HIS A O   1 
ATOM   1346  C CB  . HIS A 1 168 ? -4.693  42.604  1.857   1.00 40.20  ? 168 HIS A CB  1 
ATOM   1347  C CG  . HIS A 1 168 ? -5.691  43.673  2.191   1.00 42.97  ? 168 HIS A CG  1 
ATOM   1348  N ND1 . HIS A 1 168 ? -6.711  43.500  3.106   1.00 41.78  ? 168 HIS A ND1 1 
ATOM   1349  C CD2 . HIS A 1 168 ? -5.843  44.922  1.692   1.00 39.62  ? 168 HIS A CD2 1 
ATOM   1350  C CE1 . HIS A 1 168 ? -7.437  44.618  3.165   1.00 40.85  ? 168 HIS A CE1 1 
ATOM   1351  N NE2 . HIS A 1 168 ? -6.934  45.486  2.306   1.00 40.69  ? 168 HIS A NE2 1 
ATOM   1352  N N   . TRP A 1 169 ? -2.245  41.088  0.514   1.00 35.94  ? 169 TRP A N   1 
ATOM   1353  C CA  . TRP A 1 169 ? -1.152  40.142  0.662   1.00 33.57  ? 169 TRP A CA  1 
ATOM   1354  C C   . TRP A 1 169 ? 0.173   40.810  0.272   1.00 32.50  ? 169 TRP A C   1 
ATOM   1355  O O   . TRP A 1 169 ? 1.216   40.509  0.852   1.00 29.67  ? 169 TRP A O   1 
ATOM   1356  C CB  . TRP A 1 169 ? -1.432  38.858  -0.139  1.00 34.16  ? 169 TRP A CB  1 
ATOM   1357  C CG  . TRP A 1 169 ? -1.323  39.027  -1.632  1.00 36.50  ? 169 TRP A CG  1 
ATOM   1358  C CD1 . TRP A 1 169 ? -2.320  39.365  -2.494  1.00 38.45  ? 169 TRP A CD1 1 
ATOM   1359  C CD2 . TRP A 1 169 ? -0.135  38.871  -2.438  1.00 36.53  ? 169 TRP A CD2 1 
ATOM   1360  N NE1 . TRP A 1 169 ? -1.842  39.423  -3.772  1.00 41.33  ? 169 TRP A NE1 1 
ATOM   1361  C CE2 . TRP A 1 169 ? -0.510  39.122  -3.776  1.00 39.82  ? 169 TRP A CE2 1 
ATOM   1362  C CE3 . TRP A 1 169 ? 1.196   38.546  -2.160  1.00 34.32  ? 169 TRP A CE3 1 
ATOM   1363  C CZ2 . TRP A 1 169 ? 0.393   39.052  -4.836  1.00 39.36  ? 169 TRP A CZ2 1 
ATOM   1364  C CZ3 . TRP A 1 169 ? 2.084   38.456  -3.209  1.00 40.16  ? 169 TRP A CZ3 1 
ATOM   1365  C CH2 . TRP A 1 169 ? 1.691   38.711  -4.529  1.00 37.84  ? 169 TRP A CH2 1 
ATOM   1366  N N   . GLU A 1 170 ? 0.123   41.776  -0.657  1.00 35.63  ? 170 GLU A N   1 
ATOM   1367  C CA  . GLU A 1 170 ? 1.331   42.398  -1.189  1.00 35.58  ? 170 GLU A CA  1 
ATOM   1368  C C   . GLU A 1 170 ? 2.018   43.248  -0.131  1.00 31.56  ? 170 GLU A C   1 
ATOM   1369  O O   . GLU A 1 170 ? 3.217   43.135  0.043   1.00 27.98  ? 170 GLU A O   1 
ATOM   1370  C CB  . GLU A 1 170 ? 1.034   43.222  -2.436  1.00 35.78  ? 170 GLU A CB  1 
ATOM   1371  C CG  . GLU A 1 170 ? 0.719   42.309  -3.611  1.00 40.07  ? 170 GLU A CG  1 
ATOM   1372  C CD  . GLU A 1 170 ? 0.581   43.044  -4.917  1.00 42.45  ? 170 GLU A CD  1 
ATOM   1373  O OE1 . GLU A 1 170 ? -0.501  42.910  -5.507  1.00 47.30  ? 170 GLU A OE1 1 
ATOM   1374  O OE2 . GLU A 1 170 ? 1.534   43.737  -5.329  1.00 51.20  ? 170 GLU A OE2 1 
ATOM   1375  N N   . ALA A 1 171 ? 1.240   44.084  0.558   1.00 31.68  ? 171 ALA A N   1 
ATOM   1376  C CA  . ALA A 1 171 ? 1.758   44.890  1.649   1.00 30.54  ? 171 ALA A CA  1 
ATOM   1377  C C   . ALA A 1 171 ? 2.107   43.997  2.840   1.00 29.89  ? 171 ALA A C   1 
ATOM   1378  O O   . ALA A 1 171 ? 3.044   44.287  3.554   1.00 33.45  ? 171 ALA A O   1 
ATOM   1379  C CB  . ALA A 1 171 ? 0.756   45.976  1.989   1.00 28.70  ? 171 ALA A CB  1 
ATOM   1380  N N   . MET A 1 172 ? 1.409   42.875  3.020   1.00 28.75  ? 172 MET A N   1 
ATOM   1381  C CA  . MET A 1 172 ? 1.738   41.948  4.081   1.00 30.30  ? 172 MET A CA  1 
ATOM   1382  C C   . MET A 1 172 ? 3.132   41.375  3.851   1.00 30.63  ? 172 MET A C   1 
ATOM   1383  O O   . MET A 1 172 ? 3.929   41.259  4.788   1.00 26.63  ? 172 MET A O   1 
ATOM   1384  C CB  . MET A 1 172 ? 0.701   40.817  4.193   1.00 33.29  ? 172 MET A CB  1 
ATOM   1385  C CG  . MET A 1 172 ? -0.593  41.218  4.937   1.00 33.58  ? 172 MET A CG  1 
ATOM   1386  S SD  . MET A 1 172 ? -0.417  41.946  6.590   1.00 34.10  ? 172 MET A SD  1 
ATOM   1387  C CE  . MET A 1 172 ? 0.352   40.633  7.541   1.00 37.85  ? 172 MET A CE  1 
ATOM   1388  N N   . LEU A 1 173 ? 3.410   41.018  2.598   1.00 32.01  ? 173 LEU A N   1 
ATOM   1389  C CA  . LEU A 1 173 ? 4.687   40.419  2.220   1.00 34.03  ? 173 LEU A CA  1 
ATOM   1390  C C   . LEU A 1 173 ? 5.820   41.434  2.389   1.00 29.65  ? 173 LEU A C   1 
ATOM   1391  O O   . LEU A 1 173 ? 6.844   41.121  2.961   1.00 30.13  ? 173 LEU A O   1 
ATOM   1392  C CB  . LEU A 1 173 ? 4.595   39.890  0.781   1.00 35.65  ? 173 LEU A CB  1 
ATOM   1393  C CG  . LEU A 1 173 ? 5.882   39.338  0.160   1.00 36.91  ? 173 LEU A CG  1 
ATOM   1394  C CD1 . LEU A 1 173 ? 6.296   38.024  0.772   1.00 37.61  ? 173 LEU A CD1 1 
ATOM   1395  C CD2 . LEU A 1 173 ? 5.718   39.194  -1.326  1.00 39.80  ? 173 LEU A CD2 1 
ATOM   1396  N N   . GLU A 1 174 ? 5.624   42.655  1.904   1.00 28.90  ? 174 GLU A N   1 
ATOM   1397  C CA  . GLU A 1 174 ? 6.615   43.707  2.024   1.00 30.30  ? 174 GLU A CA  1 
ATOM   1398  C C   . GLU A 1 174 ? 6.941   43.949  3.504   1.00 32.51  ? 174 GLU A C   1 
ATOM   1399  O O   . GLU A 1 174 ? 8.096   43.912  3.914   1.00 39.00  ? 174 GLU A O   1 
ATOM   1400  C CB  . GLU A 1 174 ? 6.037   44.899  1.255   1.00 32.02  ? 174 GLU A CB  1 
ATOM   1401  C CG  . GLU A 1 174 ? 7.001   46.068  1.059   1.00 36.71  ? 174 GLU A CG  1 
ATOM   1402  C CD  . GLU A 1 174 ? 8.221   45.743  0.214   1.00 35.50  ? 174 GLU A CD  1 
ATOM   1403  O OE1 . GLU A 1 174 ? 8.230   44.784  -0.605  1.00 34.91  ? 174 GLU A OE1 1 
ATOM   1404  O OE2 . GLU A 1 174 ? 9.186   46.494  0.430   1.00 35.09  ? 174 GLU A OE2 1 
ATOM   1405  N N   . ASP A 1 175 ? 5.918   44.171  4.330   1.00 32.41  ? 175 ASP A N   1 
ATOM   1406  C CA  . ASP A 1 175 ? 6.110   44.306  5.765   1.00 27.59  ? 175 ASP A CA  1 
ATOM   1407  C C   . ASP A 1 175 ? 6.857   43.097  6.311   1.00 27.28  ? 175 ASP A C   1 
ATOM   1408  O O   . ASP A 1 175 ? 7.733   43.268  7.139   1.00 28.89  ? 175 ASP A O   1 
ATOM   1409  C CB  . ASP A 1 175 ? 4.798   44.566  6.480   1.00 26.81  ? 175 ASP A CB  1 
ATOM   1410  C CG  . ASP A 1 175 ? 4.343   46.018  6.474   1.00 28.11  ? 175 ASP A CG  1 
ATOM   1411  O OD1 . ASP A 1 175 ? 5.185   46.893  6.160   1.00 28.39  ? 175 ASP A OD1 1 
ATOM   1412  O OD2 . ASP A 1 175 ? 3.154   46.269  6.792   1.00 24.88  ? 175 ASP A OD2 1 
ATOM   1413  N N   . SER A 1 176 ? 6.527   41.883  5.866   1.00 27.30  ? 176 SER A N   1 
ATOM   1414  C CA  . SER A 1 176 ? 7.125   40.682  6.443   1.00 26.97  ? 176 SER A CA  1 
ATOM   1415  C C   . SER A 1 176 ? 8.601   40.597  6.043   1.00 29.57  ? 176 SER A C   1 
ATOM   1416  O O   . SER A 1 176 ? 9.452   40.164  6.818   1.00 30.80  ? 176 SER A O   1 
ATOM   1417  C CB  . SER A 1 176 ? 6.382   39.399  6.062   1.00 26.88  ? 176 SER A CB  1 
ATOM   1418  O OG  . SER A 1 176 ? 5.015   39.376  6.472   1.00 26.47  ? 176 SER A OG  1 
ATOM   1419  N N   . LEU A 1 177 ? 8.927   41.023  4.827   1.00 30.74  ? 177 LEU A N   1 
ATOM   1420  C CA  . LEU A 1 177 ? 10.320  41.020  4.417   1.00 31.88  ? 177 LEU A CA  1 
ATOM   1421  C C   . LEU A 1 177 ? 11.126  41.928  5.340   1.00 29.65  ? 177 LEU A C   1 
ATOM   1422  O O   . LEU A 1 177 ? 12.183  41.536  5.810   1.00 31.08  ? 177 LEU A O   1 
ATOM   1423  C CB  . LEU A 1 177 ? 10.441  41.447  2.958   1.00 32.76  ? 177 LEU A CB  1 
ATOM   1424  C CG  . LEU A 1 177 ? 10.002  40.393  1.942   1.00 34.13  ? 177 LEU A CG  1 
ATOM   1425  C CD1 . LEU A 1 177 ? 9.988   40.964  0.527   1.00 34.33  ? 177 LEU A CD1 1 
ATOM   1426  C CD2 . LEU A 1 177 ? 10.873  39.155  2.036   1.00 31.70  ? 177 LEU A CD2 1 
ATOM   1427  N N   . ASN A 1 178 ? 10.625  43.137  5.577   1.00 28.44  ? 178 ASN A N   1 
ATOM   1428  C CA  . ASN A 1 178 ? 11.306  44.084  6.433   1.00 29.38  ? 178 ASN A CA  1 
ATOM   1429  C C   . ASN A 1 178 ? 11.420  43.559  7.866   1.00 29.82  ? 178 ASN A C   1 
ATOM   1430  O O   . ASN A 1 178 ? 12.471  43.694  8.499   1.00 26.69  ? 178 ASN A O   1 
ATOM   1431  C CB  . ASN A 1 178 ? 10.598  45.425  6.407   1.00 29.21  ? 178 ASN A CB  1 
ATOM   1432  C CG  . ASN A 1 178 ? 10.716  46.058  5.047   1.00 34.21  ? 178 ASN A CG  1 
ATOM   1433  O OD1 . ASN A 1 178 ? 11.597  45.677  4.269   1.00 34.62  ? 178 ASN A OD1 1 
ATOM   1434  N ND2 . ASN A 1 178 ? 9.846   47.008  4.741   1.00 33.19  ? 178 ASN A ND2 1 
ATOM   1435  N N   . MET A 1 179 ? 10.323  43.005  8.397   1.00 29.06  ? 179 MET A N   1 
ATOM   1436  C CA  . MET A 1 179 ? 10.284  42.668  9.809   1.00 29.89  ? 179 MET A CA  1 
ATOM   1437  C C   . MET A 1 179 ? 11.194  41.472  10.074  1.00 31.31  ? 179 MET A C   1 
ATOM   1438  O O   . MET A 1 179 ? 11.959  41.475  11.035  1.00 30.78  ? 179 MET A O   1 
ATOM   1439  C CB  . MET A 1 179 ? 8.877   42.366  10.320  1.00 28.37  ? 179 MET A CB  1 
ATOM   1440  C CG  . MET A 1 179 ? 8.808   42.217  11.846  1.00 27.65  ? 179 MET A CG  1 
ATOM   1441  S SD  . MET A 1 179 ? 7.250   41.534  12.464  1.00 24.90  ? 179 MET A SD  1 
ATOM   1442  C CE  . MET A 1 179 ? 7.242   39.795  12.001  1.00 23.54  ? 179 MET A CE  1 
ATOM   1443  N N   . LEU A 1 180 ? 11.130  40.459  9.211   1.00 31.25  ? 180 LEU A N   1 
ATOM   1444  C CA  . LEU A 1 180 ? 12.030  39.332  9.362   1.00 33.40  ? 180 LEU A CA  1 
ATOM   1445  C C   . LEU A 1 180 ? 13.494  39.799  9.306   1.00 31.85  ? 180 LEU A C   1 
ATOM   1446  O O   . LEU A 1 180 ? 14.345  39.288  10.031  1.00 33.18  ? 180 LEU A O   1 
ATOM   1447  C CB  . LEU A 1 180 ? 11.708  38.276  8.309   1.00 34.16  ? 180 LEU A CB  1 
ATOM   1448  C CG  . LEU A 1 180 ? 10.379  37.537  8.491   1.00 35.04  ? 180 LEU A CG  1 
ATOM   1449  C CD1 . LEU A 1 180 ? 10.061  36.813  7.176   1.00 35.06  ? 180 LEU A CD1 1 
ATOM   1450  C CD2 . LEU A 1 180 ? 10.421  36.567  9.677   1.00 34.83  ? 180 LEU A CD2 1 
ATOM   1451  N N   . ALA A 1 181 ? 13.803  40.767  8.444   1.00 31.96  ? 181 ALA A N   1 
ATOM   1452  C CA  . ALA A 1 181 ? 15.173  41.220  8.300   1.00 31.68  ? 181 ALA A CA  1 
ATOM   1453  C C   . ALA A 1 181 ? 15.626  41.861  9.608   1.00 29.33  ? 181 ALA A C   1 
ATOM   1454  O O   . ALA A 1 181 ? 16.768  41.648  10.023  1.00 30.91  ? 181 ALA A O   1 
ATOM   1455  C CB  . ALA A 1 181 ? 15.290  42.182  7.139   1.00 33.15  ? 181 ALA A CB  1 
ATOM   1456  N N   . ALA A 1 182 ? 14.702  42.592  10.250  1.00 24.54  ? 182 ALA A N   1 
ATOM   1457  C CA  . ALA A 1 182 ? 14.981  43.321  11.479  1.00 24.40  ? 182 ALA A CA  1 
ATOM   1458  C C   . ALA A 1 182 ? 15.140  42.400  12.692  1.00 23.11  ? 182 ALA A C   1 
ATOM   1459  O O   . ALA A 1 182 ? 15.853  42.756  13.625  1.00 22.79  ? 182 ALA A O   1 
ATOM   1460  C CB  . ALA A 1 182 ? 13.930  44.364  11.735  1.00 23.74  ? 182 ALA A CB  1 
ATOM   1461  N N   . LEU A 1 183 ? 14.530  41.213  12.694  1.00 22.51  ? 183 LEU A N   1 
ATOM   1462  C CA  . LEU A 1 183 ? 14.409  40.465  13.935  1.00 24.41  ? 183 LEU A CA  1 
ATOM   1463  C C   . LEU A 1 183 ? 15.786  40.053  14.491  1.00 26.96  ? 183 LEU A C   1 
ATOM   1464  O O   . LEU A 1 183 ? 16.104  40.300  15.658  1.00 29.72  ? 183 LEU A O   1 
ATOM   1465  C CB  . LEU A 1 183 ? 13.457  39.290  13.769  1.00 24.28  ? 183 LEU A CB  1 
ATOM   1466  C CG  . LEU A 1 183 ? 11.986  39.622  13.500  1.00 24.34  ? 183 LEU A CG  1 
ATOM   1467  C CD1 . LEU A 1 183 ? 11.183  38.338  13.690  1.00 23.86  ? 183 LEU A CD1 1 
ATOM   1468  C CD2 . LEU A 1 183 ? 11.428  40.746  14.359  1.00 24.52  ? 183 LEU A CD2 1 
ATOM   1469  N N   . PRO A 1 184 ? 16.689  39.440  13.702  1.00 26.81  ? 184 PRO A N   1 
ATOM   1470  C CA  . PRO A 1 184 ? 17.990  39.067  14.232  1.00 26.48  ? 184 PRO A CA  1 
ATOM   1471  C C   . PRO A 1 184 ? 18.741  40.292  14.753  1.00 24.32  ? 184 PRO A C   1 
ATOM   1472  O O   . PRO A 1 184 ? 19.472  40.198  15.736  1.00 24.91  ? 184 PRO A O   1 
ATOM   1473  C CB  . PRO A 1 184 ? 18.703  38.407  13.025  1.00 28.46  ? 184 PRO A CB  1 
ATOM   1474  C CG  . PRO A 1 184 ? 17.603  38.049  12.094  1.00 29.90  ? 184 PRO A CG  1 
ATOM   1475  C CD  . PRO A 1 184 ? 16.534  39.108  12.280  1.00 28.97  ? 184 PRO A CD  1 
ATOM   1476  N N   . VAL A 1 185 ? 18.584  41.431  14.077  1.00 21.39  ? 185 VAL A N   1 
ATOM   1477  C CA  . VAL A 1 185 ? 19.297  42.623  14.495  1.00 23.32  ? 185 VAL A CA  1 
ATOM   1478  C C   . VAL A 1 185 ? 18.816  43.069  15.886  1.00 26.71  ? 185 VAL A C   1 
ATOM   1479  O O   . VAL A 1 185 ? 19.623  43.510  16.706  1.00 25.91  ? 185 VAL A O   1 
ATOM   1480  C CB  . VAL A 1 185 ? 19.113  43.706  13.421  1.00 23.52  ? 185 VAL A CB  1 
ATOM   1481  C CG1 . VAL A 1 185 ? 19.686  45.048  13.834  1.00 23.49  ? 185 VAL A CG1 1 
ATOM   1482  C CG2 . VAL A 1 185 ? 19.713  43.269  12.101  1.00 25.25  ? 185 VAL A CG2 1 
ATOM   1483  N N   . ILE A 1 186 ? 17.501  42.927  16.139  1.00 27.53  ? 186 ILE A N   1 
ATOM   1484  C CA  . ILE A 1 186 ? 16.844  43.383  17.353  1.00 27.40  ? 186 ILE A CA  1 
ATOM   1485  C C   . ILE A 1 186 ? 17.171  42.401  18.475  1.00 28.12  ? 186 ILE A C   1 
ATOM   1486  O O   . ILE A 1 186 ? 17.451  42.812  19.601  1.00 25.05  ? 186 ILE A O   1 
ATOM   1487  C CB  . ILE A 1 186 ? 15.323  43.523  17.130  1.00 26.89  ? 186 ILE A CB  1 
ATOM   1488  C CG1 . ILE A 1 186 ? 15.013  44.612  16.107  1.00 27.97  ? 186 ILE A CG1 1 
ATOM   1489  C CG2 . ILE A 1 186 ? 14.612  43.772  18.457  1.00 28.58  ? 186 ILE A CG2 1 
ATOM   1490  C CD1 . ILE A 1 186 ? 13.554  44.993  15.974  1.00 28.80  ? 186 ILE A CD1 1 
ATOM   1491  N N   . ALA A 1 187 ? 17.155  41.107  18.127  1.00 27.97  ? 187 ALA A N   1 
ATOM   1492  C CA  . ALA A 1 187 ? 17.506  40.039  19.050  1.00 26.94  ? 187 ALA A CA  1 
ATOM   1493  C C   . ALA A 1 187 ? 18.965  40.146  19.451  1.00 26.02  ? 187 ALA A C   1 
ATOM   1494  O O   . ALA A 1 187 ? 19.243  40.048  20.637  1.00 28.05  ? 187 ALA A O   1 
ATOM   1495  C CB  . ALA A 1 187 ? 17.252  38.692  18.424  1.00 28.44  ? 187 ALA A CB  1 
ATOM   1496  N N   . ALA A 1 188 ? 19.863  40.345  18.467  1.00 25.78  ? 188 ALA A N   1 
ATOM   1497  C CA  . ALA A 1 188 ? 21.291  40.486  18.735  1.00 27.18  ? 188 ALA A CA  1 
ATOM   1498  C C   . ALA A 1 188 ? 21.525  41.684  19.639  1.00 24.56  ? 188 ALA A C   1 
ATOM   1499  O O   . ALA A 1 188 ? 22.331  41.619  20.562  1.00 23.58  ? 188 ALA A O   1 
ATOM   1500  C CB  . ALA A 1 188 ? 22.108  40.628  17.467  1.00 28.89  ? 188 ALA A CB  1 
ATOM   1501  N N   . TYR A 1 189 ? 20.806  42.773  19.377  1.00 24.10  ? 189 TYR A N   1 
ATOM   1502  C CA  . TYR A 1 189 ? 21.069  43.997  20.108  1.00 25.77  ? 189 TYR A CA  1 
ATOM   1503  C C   . TYR A 1 189 ? 20.786  43.731  21.588  1.00 28.42  ? 189 TYR A C   1 
ATOM   1504  O O   . TYR A 1 189 ? 21.559  44.108  22.472  1.00 30.31  ? 189 TYR A O   1 
ATOM   1505  C CB  . TYR A 1 189 ? 20.260  45.148  19.505  1.00 24.61  ? 189 TYR A CB  1 
ATOM   1506  C CG  . TYR A 1 189 ? 20.672  46.497  20.067  1.00 25.21  ? 189 TYR A CG  1 
ATOM   1507  C CD1 . TYR A 1 189 ? 21.704  47.224  19.500  1.00 28.36  ? 189 TYR A CD1 1 
ATOM   1508  C CD2 . TYR A 1 189 ? 20.065  47.022  21.188  1.00 28.45  ? 189 TYR A CD2 1 
ATOM   1509  C CE1 . TYR A 1 189 ? 22.110  48.443  20.010  1.00 27.28  ? 189 TYR A CE1 1 
ATOM   1510  C CE2 . TYR A 1 189 ? 20.450  48.246  21.711  1.00 29.16  ? 189 TYR A CE2 1 
ATOM   1511  C CZ  . TYR A 1 189 ? 21.473  48.958  21.117  1.00 29.39  ? 189 TYR A CZ  1 
ATOM   1512  O OH  . TYR A 1 189 ? 21.842  50.161  21.630  1.00 34.36  ? 189 TYR A OH  1 
ATOM   1513  N N   . ILE A 1 190 ? 19.669  43.037  21.823  1.00 28.66  ? 190 ILE A N   1 
ATOM   1514  C CA  . ILE A 1 190 ? 19.195  42.731  23.158  1.00 28.59  ? 190 ILE A CA  1 
ATOM   1515  C C   . ILE A 1 190 ? 20.216  41.842  23.883  1.00 28.03  ? 190 ILE A C   1 
ATOM   1516  O O   . ILE A 1 190 ? 20.521  42.048  25.050  1.00 22.42  ? 190 ILE A O   1 
ATOM   1517  C CB  . ILE A 1 190 ? 17.806  42.080  23.060  1.00 26.38  ? 190 ILE A CB  1 
ATOM   1518  C CG1 . ILE A 1 190 ? 16.757  43.104  22.656  1.00 25.17  ? 190 ILE A CG1 1 
ATOM   1519  C CG2 . ILE A 1 190 ? 17.454  41.407  24.387  1.00 31.08  ? 190 ILE A CG2 1 
ATOM   1520  C CD1 . ILE A 1 190 ? 15.379  42.538  22.338  1.00 24.80  ? 190 ILE A CD1 1 
ATOM   1521  N N   . TYR A 1 191 ? 20.730  40.837  23.172  1.00 28.60  ? 191 TYR A N   1 
ATOM   1522  C CA  . TYR A 1 191 ? 21.717  39.917  23.706  1.00 27.74  ? 191 TYR A CA  1 
ATOM   1523  C C   . TYR A 1 191 ? 23.031  40.621  24.048  1.00 29.18  ? 191 TYR A C   1 
ATOM   1524  O O   . TYR A 1 191 ? 23.572  40.451  25.143  1.00 27.29  ? 191 TYR A O   1 
ATOM   1525  C CB  . TYR A 1 191 ? 21.957  38.859  22.635  1.00 26.48  ? 191 TYR A CB  1 
ATOM   1526  C CG  . TYR A 1 191 ? 22.785  37.688  23.124  1.00 27.82  ? 191 TYR A CG  1 
ATOM   1527  C CD1 . TYR A 1 191 ? 22.187  36.643  23.798  1.00 28.46  ? 191 TYR A CD1 1 
ATOM   1528  C CD2 . TYR A 1 191 ? 24.140  37.599  22.857  1.00 32.07  ? 191 TYR A CD2 1 
ATOM   1529  C CE1 . TYR A 1 191 ? 22.911  35.545  24.211  1.00 29.24  ? 191 TYR A CE1 1 
ATOM   1530  C CE2 . TYR A 1 191 ? 24.881  36.500  23.264  1.00 33.69  ? 191 TYR A CE2 1 
ATOM   1531  C CZ  . TYR A 1 191 ? 24.262  35.474  23.949  1.00 28.83  ? 191 TYR A CZ  1 
ATOM   1532  O OH  . TYR A 1 191 ? 24.940  34.382  24.370  1.00 29.33  ? 191 TYR A OH  1 
ATOM   1533  N N   . ARG A 1 192 ? 23.558  41.378  23.080  1.00 27.60  ? 192 ARG A N   1 
ATOM   1534  C CA  . ARG A 1 192 ? 24.828  42.045  23.263  1.00 25.87  ? 192 ARG A CA  1 
ATOM   1535  C C   . ARG A 1 192 ? 24.707  42.962  24.471  1.00 25.43  ? 192 ARG A C   1 
ATOM   1536  O O   . ARG A 1 192 ? 25.568  42.928  25.350  1.00 25.42  ? 192 ARG A O   1 
ATOM   1537  C CB  . ARG A 1 192 ? 25.269  42.766  21.982  1.00 28.63  ? 192 ARG A CB  1 
ATOM   1538  C CG  . ARG A 1 192 ? 25.461  41.864  20.769  1.00 30.49  ? 192 ARG A CG  1 
ATOM   1539  C CD  . ARG A 1 192 ? 26.546  40.811  20.999  1.00 32.40  ? 192 ARG A CD  1 
ATOM   1540  N NE  . ARG A 1 192 ? 27.851  41.439  21.279  1.00 33.05  ? 192 ARG A NE  1 
ATOM   1541  C CZ  . ARG A 1 192 ? 28.987  40.776  21.513  1.00 30.75  ? 192 ARG A CZ  1 
ATOM   1542  N NH1 . ARG A 1 192 ? 29.040  39.446  21.450  1.00 30.20  ? 192 ARG A NH1 1 
ATOM   1543  N NH2 . ARG A 1 192 ? 30.076  41.462  21.804  1.00 27.71  ? 192 ARG A NH2 1 
ATOM   1544  N N   . ARG A 1 193 ? 23.620  43.742  24.537  1.00 25.84  ? 193 ARG A N   1 
ATOM   1545  C CA  . ARG A 1 193 ? 23.473  44.747  25.589  1.00 26.38  ? 193 ARG A CA  1 
ATOM   1546  C C   . ARG A 1 193 ? 23.373  44.123  26.978  1.00 25.59  ? 193 ARG A C   1 
ATOM   1547  O O   . ARG A 1 193 ? 24.048  44.543  27.922  1.00 29.51  ? 193 ARG A O   1 
ATOM   1548  C CB  . ARG A 1 193 ? 22.255  45.659  25.390  1.00 26.72  ? 193 ARG A CB  1 
ATOM   1549  C CG  . ARG A 1 193 ? 22.055  46.671  26.512  1.00 26.47  ? 193 ARG A CG  1 
ATOM   1550  C CD  . ARG A 1 193 ? 21.029  47.714  26.171  1.00 26.72  ? 193 ARG A CD  1 
ATOM   1551  N NE  . ARG A 1 193 ? 20.890  48.734  27.216  1.00 28.39  ? 193 ARG A NE  1 
ATOM   1552  C CZ  . ARG A 1 193 ? 19.759  49.133  27.796  1.00 30.67  ? 193 ARG A CZ  1 
ATOM   1553  N NH1 . ARG A 1 193 ? 18.579  48.617  27.455  1.00 32.42  ? 193 ARG A NH1 1 
ATOM   1554  N NH2 . ARG A 1 193 ? 19.829  50.045  28.749  1.00 31.42  ? 193 ARG A NH2 1 
ATOM   1555  N N   . LYS A 1 194 ? 22.469  43.170  27.122  1.00 26.44  ? 194 LYS A N   1 
ATOM   1556  C CA  . LYS A 1 194 ? 22.209  42.544  28.408  1.00 28.82  ? 194 LYS A CA  1 
ATOM   1557  C C   . LYS A 1 194 ? 23.383  41.692  28.894  1.00 30.11  ? 194 LYS A C   1 
ATOM   1558  O O   . LYS A 1 194 ? 23.748  41.751  30.067  1.00 32.99  ? 194 LYS A O   1 
ATOM   1559  C CB  . LYS A 1 194 ? 20.964  41.658  28.296  1.00 28.95  ? 194 LYS A CB  1 
ATOM   1560  C CG  . LYS A 1 194 ? 19.640  42.431  28.238  1.00 27.26  ? 194 LYS A CG  1 
ATOM   1561  C CD  . LYS A 1 194 ? 18.434  41.499  28.254  1.00 25.61  ? 194 LYS A CD  1 
ATOM   1562  C CE  . LYS A 1 194 ? 18.223  40.784  29.562  1.00 26.90  ? 194 LYS A CE  1 
ATOM   1563  N NZ  . LYS A 1 194 ? 17.783  41.624  30.684  1.00 26.59  ? 194 LYS A NZ  1 
ATOM   1564  N N   . TYR A 1 195 ? 23.953  40.880  28.002  1.00 30.98  ? 195 TYR A N   1 
ATOM   1565  C CA  . TYR A 1 195 ? 24.804  39.773  28.409  1.00 28.55  ? 195 TYR A CA  1 
ATOM   1566  C C   . TYR A 1 195 ? 26.234  39.874  27.894  1.00 28.29  ? 195 TYR A C   1 
ATOM   1567  O O   . TYR A 1 195 ? 27.051  39.105  28.372  1.00 29.85  ? 195 TYR A O   1 
ATOM   1568  C CB  . TYR A 1 195 ? 24.252  38.476  27.824  1.00 29.52  ? 195 TYR A CB  1 
ATOM   1569  C CG  . TYR A 1 195 ? 22.790  38.215  28.145  1.00 32.13  ? 195 TYR A CG  1 
ATOM   1570  C CD1 . TYR A 1 195 ? 22.327  38.172  29.454  1.00 33.10  ? 195 TYR A CD1 1 
ATOM   1571  C CD2 . TYR A 1 195 ? 21.871  38.028  27.132  1.00 32.46  ? 195 TYR A CD2 1 
ATOM   1572  C CE1 . TYR A 1 195 ? 20.997  37.898  29.742  1.00 34.79  ? 195 TYR A CE1 1 
ATOM   1573  C CE2 . TYR A 1 195 ? 20.535  37.783  27.405  1.00 35.86  ? 195 TYR A CE2 1 
ATOM   1574  C CZ  . TYR A 1 195 ? 20.094  37.703  28.712  1.00 34.16  ? 195 TYR A CZ  1 
ATOM   1575  O OH  . TYR A 1 195 ? 18.781  37.417  28.924  1.00 31.10  ? 195 TYR A OH  1 
ATOM   1576  N N   . LYS A 1 196 ? 26.553  40.743  26.912  1.00 30.12  ? 196 LYS A N   1 
ATOM   1577  C CA  . LYS A 1 196 ? 27.912  40.767  26.358  1.00 28.98  ? 196 LYS A CA  1 
ATOM   1578  C C   . LYS A 1 196 ? 28.598  42.130  26.456  1.00 26.60  ? 196 LYS A C   1 
ATOM   1579  O O   . LYS A 1 196 ? 29.385  42.478  25.593  1.00 31.25  ? 196 LYS A O   1 
ATOM   1580  C CB  . LYS A 1 196 ? 27.907  40.298  24.894  1.00 30.44  ? 196 LYS A CB  1 
ATOM   1581  C CG  . LYS A 1 196 ? 27.539  38.810  24.707  1.00 33.22  ? 196 LYS A CG  1 
ATOM   1582  C CD  . LYS A 1 196 ? 28.477  37.823  25.402  1.00 32.97  ? 196 LYS A CD  1 
ATOM   1583  C CE  . LYS A 1 196 ? 28.099  36.386  25.224  1.00 35.12  ? 196 LYS A CE  1 
ATOM   1584  N NZ  . LYS A 1 196 ? 28.731  35.565  26.260  1.00 32.43  ? 196 LYS A NZ  1 
ATOM   1585  N N   . GLY A 1 197 ? 28.328  42.919  27.493  1.00 26.81  ? 197 GLY A N   1 
ATOM   1586  C CA  . GLY A 1 197 ? 29.113  44.121  27.736  1.00 25.80  ? 197 GLY A CA  1 
ATOM   1587  C C   . GLY A 1 197 ? 28.736  45.306  26.840  1.00 27.23  ? 197 GLY A C   1 
ATOM   1588  O O   . GLY A 1 197 ? 29.524  46.243  26.721  1.00 33.56  ? 197 GLY A O   1 
ATOM   1589  N N   . ASP A 1 198 ? 27.525  45.301  26.271  1.00 27.14  ? 198 ASP A N   1 
ATOM   1590  C CA  . ASP A 1 198 ? 26.993  46.417  25.497  1.00 28.89  ? 198 ASP A CA  1 
ATOM   1591  C C   . ASP A 1 198 ? 27.947  46.798  24.363  1.00 28.73  ? 198 ASP A C   1 
ATOM   1592  O O   . ASP A 1 198 ? 28.146  47.997  24.123  1.00 26.47  ? 198 ASP A O   1 
ATOM   1593  C CB  . ASP A 1 198 ? 26.650  47.629  26.361  1.00 28.08  ? 198 ASP A CB  1 
ATOM   1594  C CG  . ASP A 1 198 ? 25.613  48.615  25.800  1.00 29.90  ? 198 ASP A CG  1 
ATOM   1595  O OD1 . ASP A 1 198 ? 24.869  48.268  24.855  1.00 31.36  ? 198 ASP A OD1 1 
ATOM   1596  O OD2 . ASP A 1 198 ? 25.539  49.756  26.294  1.00 28.35  ? 198 ASP A OD2 1 
ATOM   1597  N N   . THR A 1 199 ? 28.533  45.781  23.703  1.00 27.72  ? 199 THR A N   1 
ATOM   1598  C CA  . THR A 1 199 ? 29.278  46.003  22.467  1.00 33.37  ? 199 THR A CA  1 
ATOM   1599  C C   . THR A 1 199 ? 28.545  45.307  21.325  1.00 32.34  ? 199 THR A C   1 
ATOM   1600  O O   . THR A 1 199 ? 28.019  44.189  21.485  1.00 30.75  ? 199 THR A O   1 
ATOM   1601  C CB  . THR A 1 199 ? 30.743  45.552  22.566  1.00 36.42  ? 199 THR A CB  1 
ATOM   1602  O OG1 . THR A 1 199 ? 30.751  44.142  22.692  1.00 32.31  ? 199 THR A OG1 1 
ATOM   1603  C CG2 . THR A 1 199 ? 31.450  46.096  23.794  1.00 41.31  ? 199 THR A CG2 1 
ATOM   1604  N N   . HIS A 1 200 ? 28.563  45.982  20.162  1.00 31.53  ? 200 HIS A N   1 
ATOM   1605  C CA  . HIS A 1 200 ? 27.663  45.666  19.056  1.00 33.83  ? 200 HIS A CA  1 
ATOM   1606  C C   . HIS A 1 200 ? 28.404  45.232  17.787  1.00 33.33  ? 200 HIS A C   1 
ATOM   1607  O O   . HIS A 1 200 ? 29.389  45.831  17.382  1.00 33.07  ? 200 HIS A O   1 
ATOM   1608  C CB  . HIS A 1 200 ? 26.650  46.805  18.897  1.00 30.81  ? 200 HIS A CB  1 
ATOM   1609  C CG  . HIS A 1 200 ? 25.945  47.022  20.203  1.00 30.09  ? 200 HIS A CG  1 
ATOM   1610  N ND1 . HIS A 1 200 ? 24.918  46.201  20.615  1.00 27.42  ? 200 HIS A ND1 1 
ATOM   1611  C CD2 . HIS A 1 200 ? 26.187  47.872  21.220  1.00 29.07  ? 200 HIS A CD2 1 
ATOM   1612  C CE1 . HIS A 1 200 ? 24.524  46.573  21.828  1.00 27.98  ? 200 HIS A CE1 1 
ATOM   1613  N NE2 . HIS A 1 200 ? 25.269  47.588  22.209  1.00 29.95  ? 200 HIS A NE2 1 
ATOM   1614  N N   . ILE A 1 201 ? 27.887  44.172  17.156  1.00 34.81  ? 201 ILE A N   1 
ATOM   1615  C CA  . ILE A 1 201 ? 28.472  43.595  15.953  1.00 33.19  ? 201 ILE A CA  1 
ATOM   1616  C C   . ILE A 1 201 ? 27.479  43.821  14.814  1.00 34.13  ? 201 ILE A C   1 
ATOM   1617  O O   . ILE A 1 201 ? 26.282  43.538  14.956  1.00 35.54  ? 201 ILE A O   1 
ATOM   1618  C CB  . ILE A 1 201 ? 28.816  42.108  16.193  1.00 32.27  ? 201 ILE A CB  1 
ATOM   1619  C CG1 . ILE A 1 201 ? 29.857  41.978  17.308  1.00 36.29  ? 201 ILE A CG1 1 
ATOM   1620  C CG2 . ILE A 1 201 ? 29.288  41.399  14.926  1.00 31.68  ? 201 ILE A CG2 1 
ATOM   1621  C CD1 . ILE A 1 201 ? 30.026  40.574  17.872  1.00 36.23  ? 201 ILE A CD1 1 
ATOM   1622  N N   . ALA A 1 202 ? 27.994  44.355  13.698  1.00 32.84  ? 202 ALA A N   1 
ATOM   1623  C CA  . ALA A 1 202 ? 27.206  44.658  12.512  1.00 31.02  ? 202 ALA A CA  1 
ATOM   1624  C C   . ALA A 1 202 ? 26.818  43.381  11.765  1.00 31.34  ? 202 ALA A C   1 
ATOM   1625  O O   . ALA A 1 202 ? 27.510  42.358  11.822  1.00 29.06  ? 202 ALA A O   1 
ATOM   1626  C CB  . ALA A 1 202 ? 27.982  45.578  11.592  1.00 31.16  ? 202 ALA A CB  1 
ATOM   1627  N N   . PRO A 1 203 ? 25.688  43.434  11.021  1.00 31.07  ? 203 PRO A N   1 
ATOM   1628  C CA  . PRO A 1 203 ? 25.326  42.375  10.088  1.00 28.54  ? 203 PRO A CA  1 
ATOM   1629  C C   . PRO A 1 203 ? 26.513  42.118  9.183   1.00 31.59  ? 203 PRO A C   1 
ATOM   1630  O O   . PRO A 1 203 ? 27.180  43.065  8.772   1.00 36.35  ? 203 PRO A O   1 
ATOM   1631  C CB  . PRO A 1 203 ? 24.141  42.932  9.295   1.00 27.33  ? 203 PRO A CB  1 
ATOM   1632  C CG  . PRO A 1 203 ? 23.604  44.085  10.114  1.00 28.45  ? 203 PRO A CG  1 
ATOM   1633  C CD  . PRO A 1 203 ? 24.695  44.528  11.064  1.00 29.78  ? 203 PRO A CD  1 
ATOM   1634  N N   . ASP A 1 204 ? 26.755  40.839  8.891   1.00 35.63  ? 204 ASP A N   1 
ATOM   1635  C CA  . ASP A 1 204 ? 27.621  40.440  7.799   1.00 38.43  ? 204 ASP A CA  1 
ATOM   1636  C C   . ASP A 1 204 ? 26.770  40.394  6.534   1.00 38.05  ? 204 ASP A C   1 
ATOM   1637  O O   . ASP A 1 204 ? 25.822  39.611  6.465   1.00 39.44  ? 204 ASP A O   1 
ATOM   1638  C CB  . ASP A 1 204 ? 28.251  39.079  8.070   1.00 39.71  ? 204 ASP A CB  1 
ATOM   1639  C CG  . ASP A 1 204 ? 29.425  38.676  7.179   1.00 40.97  ? 204 ASP A CG  1 
ATOM   1640  O OD1 . ASP A 1 204 ? 29.379  38.949  5.945   1.00 40.45  ? 204 ASP A OD1 1 
ATOM   1641  O OD2 . ASP A 1 204 ? 30.382  38.075  7.727   1.00 44.30  ? 204 ASP A OD2 1 
ATOM   1642  N N   . PRO A 1 205 ? 27.075  41.196  5.488   1.00 43.48  ? 205 PRO A N   1 
ATOM   1643  C CA  . PRO A 1 205 ? 26.333  41.113  4.222   1.00 39.33  ? 205 PRO A CA  1 
ATOM   1644  C C   . PRO A 1 205 ? 26.404  39.803  3.434   1.00 38.83  ? 205 PRO A C   1 
ATOM   1645  O O   . PRO A 1 205 ? 25.666  39.652  2.463   1.00 37.05  ? 205 PRO A O   1 
ATOM   1646  C CB  . PRO A 1 205 ? 26.884  42.286  3.378   1.00 38.45  ? 205 PRO A CB  1 
ATOM   1647  C CG  . PRO A 1 205 ? 27.550  43.205  4.378   1.00 43.39  ? 205 PRO A CG  1 
ATOM   1648  C CD  . PRO A 1 205 ? 28.071  42.283  5.489   1.00 45.89  ? 205 PRO A CD  1 
ATOM   1649  N N   . ASN A 1 206 ? 27.285  38.868  3.816   1.00 37.30  ? 206 ASN A N   1 
ATOM   1650  C CA  . ASN A 1 206 ? 27.502  37.664  3.026   1.00 40.27  ? 206 ASN A CA  1 
ATOM   1651  C C   . ASN A 1 206 ? 27.004  36.406  3.742   1.00 41.67  ? 206 ASN A C   1 
ATOM   1652  O O   . ASN A 1 206 ? 27.178  35.306  3.222   1.00 42.87  ? 206 ASN A O   1 
ATOM   1653  C CB  . ASN A 1 206 ? 28.976  37.541  2.638   1.00 43.93  ? 206 ASN A CB  1 
ATOM   1654  C CG  . ASN A 1 206 ? 29.451  38.782  1.918   1.00 45.19  ? 206 ASN A CG  1 
ATOM   1655  O OD1 . ASN A 1 206 ? 28.960  39.088  0.830   1.00 45.35  ? 206 ASN A OD1 1 
ATOM   1656  N ND2 . ASN A 1 206 ? 30.359  39.537  2.515   1.00 49.23  ? 206 ASN A ND2 1 
ATOM   1657  N N   . LEU A 1 207 ? 26.424  36.556  4.942   1.00 37.88  ? 207 LEU A N   1 
ATOM   1658  C CA  . LEU A 1 207 ? 25.915  35.428  5.700   1.00 34.22  ? 207 LEU A CA  1 
ATOM   1659  C C   . LEU A 1 207 ? 24.409  35.344  5.475   1.00 31.81  ? 207 LEU A C   1 
ATOM   1660  O O   . LEU A 1 207 ? 23.728  36.347  5.238   1.00 30.05  ? 207 LEU A O   1 
ATOM   1661  C CB  . LEU A 1 207 ? 26.240  35.542  7.192   1.00 37.17  ? 207 LEU A CB  1 
ATOM   1662  C CG  . LEU A 1 207 ? 27.697  35.339  7.619   1.00 36.54  ? 207 LEU A CG  1 
ATOM   1663  C CD1 . LEU A 1 207 ? 27.892  35.758  9.042   1.00 37.62  ? 207 LEU A CD1 1 
ATOM   1664  C CD2 . LEU A 1 207 ? 28.125  33.890  7.500   1.00 38.30  ? 207 LEU A CD2 1 
ATOM   1665  N N   . ASP A 1 208 ? 23.916  34.114  5.520   1.00 29.83  ? 208 ASP A N   1 
ATOM   1666  C CA  . ASP A 1 208 ? 22.488  33.874  5.503   1.00 34.91  ? 208 ASP A CA  1 
ATOM   1667  C C   . ASP A 1 208 ? 21.905  34.268  6.857   1.00 35.74  ? 208 ASP A C   1 
ATOM   1668  O O   . ASP A 1 208 ? 22.653  34.528  7.792   1.00 37.39  ? 208 ASP A O   1 
ATOM   1669  C CB  . ASP A 1 208 ? 22.205  32.411  5.230   1.00 34.09  ? 208 ASP A CB  1 
ATOM   1670  C CG  . ASP A 1 208 ? 22.916  31.510  6.211   1.00 36.10  ? 208 ASP A CG  1 
ATOM   1671  O OD1 . ASP A 1 208 ? 24.163  31.533  6.176   1.00 42.81  ? 208 ASP A OD1 1 
ATOM   1672  O OD2 . ASP A 1 208 ? 22.223  30.879  7.030   1.00 36.68  ? 208 ASP A OD2 1 
ATOM   1673  N N   . TRP A 1 209 ? 20.568  34.239  6.947   1.00 35.61  ? 209 TRP A N   1 
ATOM   1674  C CA  . TRP A 1 209 ? 19.780  34.921  7.971   1.00 32.05  ? 209 TRP A CA  1 
ATOM   1675  C C   . TRP A 1 209 ? 20.051  34.374  9.373   1.00 30.58  ? 209 TRP A C   1 
ATOM   1676  O O   . TRP A 1 209 ? 20.223  35.158  10.292  1.00 29.86  ? 209 TRP A O   1 
ATOM   1677  C CB  . TRP A 1 209 ? 18.305  34.772  7.575   1.00 30.87  ? 209 TRP A CB  1 
ATOM   1678  C CG  . TRP A 1 209 ? 17.272  35.489  8.405   1.00 31.05  ? 209 TRP A CG  1 
ATOM   1679  C CD1 . TRP A 1 209 ? 16.922  36.810  8.404   1.00 30.50  ? 209 TRP A CD1 1 
ATOM   1680  C CD2 . TRP A 1 209 ? 16.324  34.834  9.266   1.00 29.32  ? 209 TRP A CD2 1 
ATOM   1681  N NE1 . TRP A 1 209 ? 15.865  37.029  9.250   1.00 25.98  ? 209 TRP A NE1 1 
ATOM   1682  C CE2 . TRP A 1 209 ? 15.470  35.833  9.778   1.00 27.54  ? 209 TRP A CE2 1 
ATOM   1683  C CE3 . TRP A 1 209 ? 16.139  33.507  9.658   1.00 27.94  ? 209 TRP A CE3 1 
ATOM   1684  C CZ2 . TRP A 1 209 ? 14.441  35.535  10.663  1.00 28.02  ? 209 TRP A CZ2 1 
ATOM   1685  C CZ3 . TRP A 1 209 ? 15.110  33.215  10.525  1.00 29.86  ? 209 TRP A CZ3 1 
ATOM   1686  C CH2 . TRP A 1 209 ? 14.272  34.215  11.014  1.00 29.49  ? 209 TRP A CH2 1 
ATOM   1687  N N   . SER A 1 210 ? 20.078  33.038  9.517   1.00 28.83  ? 210 SER A N   1 
ATOM   1688  C CA  . SER A 1 210 ? 20.345  32.362  10.773  1.00 30.20  ? 210 SER A CA  1 
ATOM   1689  C C   . SER A 1 210 ? 21.772  32.617  11.248  1.00 32.73  ? 210 SER A C   1 
ATOM   1690  O O   . SER A 1 210 ? 22.004  32.887  12.418  1.00 34.97  ? 210 SER A O   1 
ATOM   1691  C CB  . SER A 1 210 ? 20.123  30.887  10.606  1.00 32.11  ? 210 SER A CB  1 
ATOM   1692  O OG  . SER A 1 210 ? 18.807  30.679  10.127  1.00 36.16  ? 210 SER A OG  1 
ATOM   1693  N N   . ALA A 1 211 ? 22.726  32.474  10.328  1.00 31.66  ? 211 ALA A N   1 
ATOM   1694  C CA  . ALA A 1 211 ? 24.132  32.627  10.640  1.00 31.02  ? 211 ALA A CA  1 
ATOM   1695  C C   . ALA A 1 211 ? 24.412  34.039  11.130  1.00 33.29  ? 211 ALA A C   1 
ATOM   1696  O O   . ALA A 1 211 ? 25.150  34.197  12.103  1.00 35.50  ? 211 ALA A O   1 
ATOM   1697  C CB  . ALA A 1 211 ? 24.952  32.297  9.419   1.00 34.27  ? 211 ALA A CB  1 
ATOM   1698  N N   . ASN A 1 212 ? 23.821  35.043  10.452  1.00 32.77  ? 212 ASN A N   1 
ATOM   1699  C CA  . ASN A 1 212 ? 23.957  36.435  10.853  1.00 32.83  ? 212 ASN A CA  1 
ATOM   1700  C C   . ASN A 1 212 ? 23.495  36.614  12.296  1.00 33.15  ? 212 ASN A C   1 
ATOM   1701  O O   . ASN A 1 212 ? 24.045  37.437  13.030  1.00 32.86  ? 212 ASN A O   1 
ATOM   1702  C CB  . ASN A 1 212 ? 23.158  37.402  9.990   1.00 36.26  ? 212 ASN A CB  1 
ATOM   1703  C CG  . ASN A 1 212 ? 24.030  38.397  9.275   1.00 41.69  ? 212 ASN A CG  1 
ATOM   1704  O OD1 . ASN A 1 212 ? 24.944  38.953  9.896   1.00 40.29  ? 212 ASN A OD1 1 
ATOM   1705  N ND2 . ASN A 1 212 ? 23.770  38.624  7.988   1.00 48.59  ? 212 ASN A ND2 1 
ATOM   1706  N N   . LEU A 1 213 ? 22.461  35.859  12.687  1.00 32.30  ? 213 LEU A N   1 
ATOM   1707  C CA  . LEU A 1 213 ? 21.963  35.950  14.049  1.00 34.28  ? 213 LEU A CA  1 
ATOM   1708  C C   . LEU A 1 213 ? 23.099  35.545  14.981  1.00 30.89  ? 213 LEU A C   1 
ATOM   1709  O O   . LEU A 1 213 ? 23.461  36.305  15.875  1.00 26.94  ? 213 LEU A O   1 
ATOM   1710  C CB  . LEU A 1 213 ? 20.704  35.134  14.344  1.00 34.26  ? 213 LEU A CB  1 
ATOM   1711  C CG  . LEU A 1 213 ? 20.200  35.277  15.781  1.00 32.18  ? 213 LEU A CG  1 
ATOM   1712  C CD1 . LEU A 1 213 ? 20.126  36.734  16.228  1.00 30.11  ? 213 LEU A CD1 1 
ATOM   1713  C CD2 . LEU A 1 213 ? 18.857  34.587  15.898  1.00 35.32  ? 213 LEU A CD2 1 
ATOM   1714  N N   . ALA A 1 214 ? 23.678  34.372  14.708  1.00 28.93  ? 214 ALA A N   1 
ATOM   1715  C CA  . ALA A 1 214 ? 24.779  33.881  15.512  1.00 29.84  ? 214 ALA A CA  1 
ATOM   1716  C C   . ALA A 1 214 ? 25.892  34.929  15.542  1.00 30.68  ? 214 ALA A C   1 
ATOM   1717  O O   . ALA A 1 214 ? 26.356  35.286  16.622  1.00 34.13  ? 214 ALA A O   1 
ATOM   1718  C CB  . ALA A 1 214 ? 25.246  32.541  14.997  1.00 29.51  ? 214 ALA A CB  1 
ATOM   1719  N N   . HIS A 1 215 ? 26.265  35.449  14.361  1.00 29.53  ? 215 HIS A N   1 
ATOM   1720  C CA  . HIS A 1 215 ? 27.399  36.350  14.203  1.00 26.81  ? 215 HIS A CA  1 
ATOM   1721  C C   . HIS A 1 215 ? 27.193  37.619  15.021  1.00 28.98  ? 215 HIS A C   1 
ATOM   1722  O O   . HIS A 1 215 ? 28.105  38.054  15.692  1.00 31.99  ? 215 HIS A O   1 
ATOM   1723  C CB  . HIS A 1 215 ? 27.605  36.723  12.722  1.00 26.14  ? 215 HIS A CB  1 
ATOM   1724  C CG  . HIS A 1 215 ? 28.629  37.781  12.430  1.00 22.84  ? 215 HIS A CG  1 
ATOM   1725  N ND1 . HIS A 1 215 ? 29.991  37.568  12.530  1.00 22.64  ? 215 HIS A ND1 1 
ATOM   1726  C CD2 . HIS A 1 215 ? 28.471  39.068  12.048  1.00 21.48  ? 215 HIS A CD2 1 
ATOM   1727  C CE1 . HIS A 1 215 ? 30.627  38.690  12.190  1.00 24.14  ? 215 HIS A CE1 1 
ATOM   1728  N NE2 . HIS A 1 215 ? 29.728  39.610  11.891  1.00 23.55  ? 215 HIS A NE2 1 
ATOM   1729  N N   . MET A 1 216 ? 26.005  38.223  14.975  1.00 29.58  ? 216 MET A N   1 
ATOM   1730  C CA  . MET A 1 216 ? 25.774  39.475  15.682  1.00 27.61  ? 216 MET A CA  1 
ATOM   1731  C C   . MET A 1 216 ? 25.686  39.258  17.193  1.00 25.43  ? 216 MET A C   1 
ATOM   1732  O O   . MET A 1 216 ? 25.865  40.210  17.944  1.00 24.06  ? 216 MET A O   1 
ATOM   1733  C CB  . MET A 1 216 ? 24.501  40.139  15.158  1.00 29.12  ? 216 MET A CB  1 
ATOM   1734  C CG  . MET A 1 216 ? 24.601  40.538  13.696  1.00 27.22  ? 216 MET A CG  1 
ATOM   1735  S SD  . MET A 1 216 ? 23.253  41.628  13.209  1.00 28.28  ? 216 MET A SD  1 
ATOM   1736  C CE  . MET A 1 216 ? 22.042  40.310  13.042  1.00 31.03  ? 216 MET A CE  1 
ATOM   1737  N N   . MET A 1 217 ? 25.445  38.003  17.622  1.00 27.32  ? 217 MET A N   1 
ATOM   1738  C CA  . MET A 1 217 ? 25.454  37.609  19.031  1.00 29.01  ? 217 MET A CA  1 
ATOM   1739  C C   . MET A 1 217 ? 26.877  37.309  19.514  1.00 30.58  ? 217 MET A C   1 
ATOM   1740  O O   . MET A 1 217 ? 27.139  37.324  20.725  1.00 32.17  ? 217 MET A O   1 
ATOM   1741  C CB  . MET A 1 217 ? 24.599  36.361  19.300  1.00 27.70  ? 217 MET A CB  1 
ATOM   1742  C CG  . MET A 1 217 ? 23.075  36.533  19.110  1.00 26.50  ? 217 MET A CG  1 
ATOM   1743  S SD  . MET A 1 217 ? 22.156  34.978  19.244  1.00 26.40  ? 217 MET A SD  1 
ATOM   1744  C CE  . MET A 1 217 ? 22.600  34.359  20.872  1.00 26.01  ? 217 MET A CE  1 
ATOM   1745  N N   . GLY A 1 218 ? 27.773  37.013  18.561  1.00 30.33  ? 218 GLY A N   1 
ATOM   1746  C CA  . GLY A 1 218 ? 29.202  36.895  18.816  1.00 29.20  ? 218 GLY A CA  1 
ATOM   1747  C C   . GLY A 1 218 ? 29.716  35.470  18.620  1.00 29.70  ? 218 GLY A C   1 
ATOM   1748  O O   . GLY A 1 218 ? 30.734  35.132  19.186  1.00 32.83  ? 218 GLY A O   1 
ATOM   1749  N N   . PHE A 1 219 ? 29.037  34.645  17.818  1.00 32.22  ? 219 PHE A N   1 
ATOM   1750  C CA  . PHE A 1 219 ? 29.409  33.247  17.623  1.00 36.86  ? 219 PHE A CA  1 
ATOM   1751  C C   . PHE A 1 219 ? 29.564  32.962  16.126  1.00 39.38  ? 219 PHE A C   1 
ATOM   1752  O O   . PHE A 1 219 ? 28.622  33.176  15.371  1.00 42.94  ? 219 PHE A O   1 
ATOM   1753  C CB  . PHE A 1 219 ? 28.343  32.305  18.198  1.00 37.97  ? 219 PHE A CB  1 
ATOM   1754  C CG  . PHE A 1 219 ? 28.019  32.524  19.669  1.00 38.52  ? 219 PHE A CG  1 
ATOM   1755  C CD1 . PHE A 1 219 ? 27.058  33.454  20.056  1.00 36.35  ? 219 PHE A CD1 1 
ATOM   1756  C CD2 . PHE A 1 219 ? 28.668  31.788  20.664  1.00 39.28  ? 219 PHE A CD2 1 
ATOM   1757  C CE1 . PHE A 1 219 ? 26.770  33.662  21.399  1.00 35.02  ? 219 PHE A CE1 1 
ATOM   1758  C CE2 . PHE A 1 219 ? 28.372  31.998  22.001  1.00 39.08  ? 219 PHE A CE2 1 
ATOM   1759  C CZ  . PHE A 1 219 ? 27.422  32.940  22.365  1.00 37.71  ? 219 PHE A CZ  1 
ATOM   1760  N N   . ASP A 1 220 ? 30.734  32.447  15.710  1.00 37.24  ? 220 ASP A N   1 
ATOM   1761  C CA  . ASP A 1 220 ? 31.040  32.288  14.297  1.00 36.19  ? 220 ASP A CA  1 
ATOM   1762  C C   . ASP A 1 220 ? 31.507  30.884  13.912  1.00 32.70  ? 220 ASP A C   1 
ATOM   1763  O O   . ASP A 1 220 ? 31.791  30.660  12.746  1.00 35.16  ? 220 ASP A O   1 
ATOM   1764  C CB  . ASP A 1 220 ? 32.013  33.354  13.834  1.00 33.20  ? 220 ASP A CB  1 
ATOM   1765  C CG  . ASP A 1 220 ? 31.421  34.750  13.820  1.00 32.92  ? 220 ASP A CG  1 
ATOM   1766  O OD1 . ASP A 1 220 ? 30.498  34.997  13.008  1.00 31.80  ? 220 ASP A OD1 1 
ATOM   1767  O OD2 . ASP A 1 220 ? 31.879  35.562  14.624  1.00 31.52  ? 220 ASP A OD2 1 
ATOM   1768  N N   . ASP A 1 221 ? 31.541  29.918  14.831  1.00 34.95  ? 221 ASP A N   1 
ATOM   1769  C CA  . ASP A 1 221 ? 31.864  28.558  14.423  1.00 40.66  ? 221 ASP A CA  1 
ATOM   1770  C C   . ASP A 1 221 ? 30.806  28.097  13.437  1.00 43.05  ? 221 ASP A C   1 
ATOM   1771  O O   . ASP A 1 221 ? 29.621  28.349  13.648  1.00 49.45  ? 221 ASP A O   1 
ATOM   1772  C CB  . ASP A 1 221 ? 31.813  27.532  15.544  1.00 42.80  ? 221 ASP A CB  1 
ATOM   1773  C CG  . ASP A 1 221 ? 32.948  27.563  16.555  1.00 53.22  ? 221 ASP A CG  1 
ATOM   1774  O OD1 . ASP A 1 221 ? 33.924  28.309  16.310  1.00 55.81  ? 221 ASP A OD1 1 
ATOM   1775  O OD2 . ASP A 1 221 ? 32.829  26.860  17.598  1.00 56.94  ? 221 ASP A OD2 1 
ATOM   1776  N N   . PHE A 1 222 ? 31.235  27.376  12.404  1.00 40.65  ? 222 PHE A N   1 
ATOM   1777  C CA  . PHE A 1 222 ? 30.306  26.754  11.464  1.00 42.31  ? 222 PHE A CA  1 
ATOM   1778  C C   . PHE A 1 222 ? 29.244  25.903  12.173  1.00 39.14  ? 222 PHE A C   1 
ATOM   1779  O O   . PHE A 1 222 ? 28.071  25.904  11.797  1.00 39.35  ? 222 PHE A O   1 
ATOM   1780  C CB  . PHE A 1 222 ? 31.174  25.939  10.508  1.00 41.16  ? 222 PHE A CB  1 
ATOM   1781  C CG  . PHE A 1 222 ? 30.443  24.935  9.636   1.00 45.36  ? 222 PHE A CG  1 
ATOM   1782  C CD1 . PHE A 1 222 ? 29.918  25.324  8.408   1.00 45.54  ? 222 PHE A CD1 1 
ATOM   1783  C CD2 . PHE A 1 222 ? 30.341  23.591  10.016  1.00 50.90  ? 222 PHE A CD2 1 
ATOM   1784  C CE1 . PHE A 1 222 ? 29.283  24.394  7.591   1.00 48.98  ? 222 PHE A CE1 1 
ATOM   1785  C CE2 . PHE A 1 222 ? 29.682  22.666  9.204   1.00 48.92  ? 222 PHE A CE2 1 
ATOM   1786  C CZ  . PHE A 1 222 ? 29.163  23.071  7.993   1.00 48.26  ? 222 PHE A CZ  1 
ATOM   1787  N N   . GLU A 1 223 ? 29.651  25.157  13.198  1.00 38.81  ? 223 GLU A N   1 
ATOM   1788  C CA  . GLU A 1 223 ? 28.737  24.255  13.873  1.00 40.31  ? 223 GLU A CA  1 
ATOM   1789  C C   . GLU A 1 223 ? 27.567  25.051  14.453  1.00 38.96  ? 223 GLU A C   1 
ATOM   1790  O O   . GLU A 1 223 ? 26.442  24.552  14.522  1.00 36.84  ? 223 GLU A O   1 
ATOM   1791  C CB  . GLU A 1 223 ? 29.498  23.446  14.923  1.00 44.32  ? 223 GLU A CB  1 
ATOM   1792  C CG  . GLU A 1 223 ? 30.265  22.250  14.357  1.00 50.62  ? 223 GLU A CG  1 
ATOM   1793  C CD  . GLU A 1 223 ? 30.867  21.326  15.425  1.00 63.91  ? 223 GLU A CD  1 
ATOM   1794  O OE1 . GLU A 1 223 ? 32.094  21.078  15.373  1.00 67.63  ? 223 GLU A OE1 1 
ATOM   1795  O OE2 . GLU A 1 223 ? 30.135  20.848  16.331  1.00 66.18  ? 223 GLU A OE2 1 
ATOM   1796  N N   . VAL A 1 224 ? 27.856  26.298  14.860  1.00 38.45  ? 224 VAL A N   1 
ATOM   1797  C CA  . VAL A 1 224 ? 26.871  27.190  15.450  1.00 35.47  ? 224 VAL A CA  1 
ATOM   1798  C C   . VAL A 1 224 ? 25.945  27.693  14.342  1.00 33.20  ? 224 VAL A C   1 
ATOM   1799  O O   . VAL A 1 224 ? 24.717  27.604  14.484  1.00 31.39  ? 224 VAL A O   1 
ATOM   1800  C CB  . VAL A 1 224 ? 27.526  28.344  16.244  1.00 33.85  ? 224 VAL A CB  1 
ATOM   1801  C CG1 . VAL A 1 224 ? 26.521  29.376  16.740  1.00 37.89  ? 224 VAL A CG1 1 
ATOM   1802  C CG2 . VAL A 1 224 ? 28.306  27.831  17.432  1.00 32.75  ? 224 VAL A CG2 1 
ATOM   1803  N N   . TYR A 1 225 ? 26.545  28.185  13.245  1.00 29.70  ? 225 TYR A N   1 
ATOM   1804  C CA  . TYR A 1 225 ? 25.794  28.550  12.052  1.00 30.35  ? 225 TYR A CA  1 
ATOM   1805  C C   . TYR A 1 225 ? 24.832  27.408  11.709  1.00 32.96  ? 225 TYR A C   1 
ATOM   1806  O O   . TYR A 1 225 ? 23.640  27.624  11.461  1.00 28.88  ? 225 TYR A O   1 
ATOM   1807  C CB  . TYR A 1 225 ? 26.711  28.906  10.875  1.00 29.79  ? 225 TYR A CB  1 
ATOM   1808  C CG  . TYR A 1 225 ? 27.537  30.187  10.976  1.00 31.87  ? 225 TYR A CG  1 
ATOM   1809  C CD1 . TYR A 1 225 ? 27.394  31.072  12.045  1.00 34.46  ? 225 TYR A CD1 1 
ATOM   1810  C CD2 . TYR A 1 225 ? 28.434  30.550  9.969   1.00 33.13  ? 225 TYR A CD2 1 
ATOM   1811  C CE1 . TYR A 1 225 ? 28.131  32.245  12.131  1.00 34.31  ? 225 TYR A CE1 1 
ATOM   1812  C CE2 . TYR A 1 225 ? 29.190  31.713  10.053  1.00 34.38  ? 225 TYR A CE2 1 
ATOM   1813  C CZ  . TYR A 1 225 ? 29.037  32.564  11.136  1.00 36.38  ? 225 TYR A CZ  1 
ATOM   1814  O OH  . TYR A 1 225 ? 29.745  33.726  11.257  1.00 37.87  ? 225 TYR A OH  1 
ATOM   1815  N N   . GLU A 1 226 ? 25.335  26.172  11.776  1.00 33.39  ? 226 GLU A N   1 
ATOM   1816  C CA  . GLU A 1 226 ? 24.505  25.032  11.441  1.00 36.46  ? 226 GLU A CA  1 
ATOM   1817  C C   . GLU A 1 226 ? 23.410  24.797  12.478  1.00 34.95  ? 226 GLU A C   1 
ATOM   1818  O O   . GLU A 1 226 ? 22.271  24.509  12.094  1.00 33.90  ? 226 GLU A O   1 
ATOM   1819  C CB  . GLU A 1 226 ? 25.373  23.803  11.205  1.00 38.63  ? 226 GLU A CB  1 
ATOM   1820  C CG  . GLU A 1 226 ? 26.139  23.913  9.892   1.00 39.06  ? 226 GLU A CG  1 
ATOM   1821  C CD  . GLU A 1 226 ? 25.305  23.711  8.649   1.00 34.53  ? 226 GLU A CD  1 
ATOM   1822  O OE1 . GLU A 1 226 ? 25.157  24.711  7.925   1.00 33.43  ? 226 GLU A OE1 1 
ATOM   1823  O OE2 . GLU A 1 226 ? 24.862  22.561  8.407   1.00 32.43  ? 226 GLU A OE2 1 
ATOM   1824  N N   . LEU A 1 227 ? 23.748  24.885  13.771  1.00 29.86  ? 227 LEU A N   1 
ATOM   1825  C CA  . LEU A 1 227 ? 22.726  24.724  14.791  1.00 29.38  ? 227 LEU A CA  1 
ATOM   1826  C C   . LEU A 1 227 ? 21.622  25.769  14.595  1.00 27.38  ? 227 LEU A C   1 
ATOM   1827  O O   . LEU A 1 227 ? 20.440  25.441  14.643  1.00 24.45  ? 227 LEU A O   1 
ATOM   1828  C CB  . LEU A 1 227 ? 23.335  24.834  16.187  1.00 31.90  ? 227 LEU A CB  1 
ATOM   1829  C CG  . LEU A 1 227 ? 22.343  24.879  17.363  1.00 29.55  ? 227 LEU A CG  1 
ATOM   1830  C CD1 . LEU A 1 227 ? 21.365  23.716  17.327  1.00 29.52  ? 227 LEU A CD1 1 
ATOM   1831  C CD2 . LEU A 1 227 ? 23.082  24.897  18.679  1.00 30.52  ? 227 LEU A CD2 1 
ATOM   1832  N N   . PHE A 1 228 ? 22.012  27.036  14.378  1.00 27.21  ? 228 PHE A N   1 
ATOM   1833  C CA  . PHE A 1 228 ? 21.045  28.114  14.212  1.00 26.81  ? 228 PHE A CA  1 
ATOM   1834  C C   . PHE A 1 228 ? 20.144  27.846  13.005  1.00 27.92  ? 228 PHE A C   1 
ATOM   1835  O O   . PHE A 1 228 ? 18.935  28.077  13.072  1.00 28.76  ? 228 PHE A O   1 
ATOM   1836  C CB  . PHE A 1 228 ? 21.642  29.526  14.147  1.00 24.56  ? 228 PHE A CB  1 
ATOM   1837  C CG  . PHE A 1 228 ? 21.925  30.142  15.508  1.00 23.09  ? 228 PHE A CG  1 
ATOM   1838  C CD1 . PHE A 1 228 ? 22.604  29.440  16.488  1.00 23.96  ? 228 PHE A CD1 1 
ATOM   1839  C CD2 . PHE A 1 228 ? 21.498  31.419  15.816  1.00 25.37  ? 228 PHE A CD2 1 
ATOM   1840  C CE1 . PHE A 1 228 ? 22.873  30.001  17.717  1.00 22.51  ? 228 PHE A CE1 1 
ATOM   1841  C CE2 . PHE A 1 228 ? 21.778  31.979  17.057  1.00 26.08  ? 228 PHE A CE2 1 
ATOM   1842  C CZ  . PHE A 1 228 ? 22.472  31.268  17.995  1.00 24.49  ? 228 PHE A CZ  1 
ATOM   1843  N N   . ARG A 1 229 ? 20.704  27.321  11.917  1.00 29.50  ? 229 ARG A N   1 
ATOM   1844  C CA  . ARG A 1 229 ? 19.883  27.055  10.746  1.00 29.64  ? 229 ARG A CA  1 
ATOM   1845  C C   . ARG A 1 229 ? 18.822  26.005  11.065  1.00 27.95  ? 229 ARG A C   1 
ATOM   1846  O O   . ARG A 1 229 ? 17.655  26.199  10.783  1.00 32.83  ? 229 ARG A O   1 
ATOM   1847  C CB  . ARG A 1 229 ? 20.799  26.666  9.592   1.00 33.09  ? 229 ARG A CB  1 
ATOM   1848  C CG  . ARG A 1 229 ? 21.583  27.850  9.046   1.00 36.85  ? 229 ARG A CG  1 
ATOM   1849  C CD  . ARG A 1 229 ? 22.863  27.335  8.362   1.00 36.03  ? 229 ARG A CD  1 
ATOM   1850  N NE  . ARG A 1 229 ? 23.711  28.436  7.898   1.00 34.07  ? 229 ARG A NE  1 
ATOM   1851  C CZ  . ARG A 1 229 ? 25.015  28.340  7.656   1.00 33.68  ? 229 ARG A CZ  1 
ATOM   1852  N NH1 . ARG A 1 229 ? 25.689  27.235  7.961   1.00 33.29  ? 229 ARG A NH1 1 
ATOM   1853  N NH2 . ARG A 1 229 ? 25.645  29.368  7.120   1.00 30.87  ? 229 ARG A NH2 1 
ATOM   1854  N N   . LEU A 1 230 ? 19.220  24.898  11.673  1.00 29.80  ? 230 LEU A N   1 
ATOM   1855  C CA  . LEU A 1 230 ? 18.292  23.879  12.143  1.00 30.62  ? 230 LEU A CA  1 
ATOM   1856  C C   . LEU A 1 230 ? 17.309  24.461  13.158  1.00 29.98  ? 230 LEU A C   1 
ATOM   1857  O O   . LEU A 1 230 ? 16.102  24.224  13.067  1.00 33.13  ? 230 LEU A O   1 
ATOM   1858  C CB  . LEU A 1 230 ? 19.053  22.694  12.744  1.00 31.66  ? 230 LEU A CB  1 
ATOM   1859  C CG  . LEU A 1 230 ? 18.188  21.529  13.253  1.00 34.12  ? 230 LEU A CG  1 
ATOM   1860  C CD1 . LEU A 1 230 ? 17.240  21.011  12.195  1.00 34.14  ? 230 LEU A CD1 1 
ATOM   1861  C CD2 . LEU A 1 230 ? 19.003  20.363  13.795  1.00 30.79  ? 230 LEU A CD2 1 
ATOM   1862  N N   . TYR A 1 231 ? 17.813  25.209  14.131  1.00 26.28  ? 231 TYR A N   1 
ATOM   1863  C CA  . TYR A 1 231 ? 16.930  25.693  15.166  1.00 29.86  ? 231 TYR A CA  1 
ATOM   1864  C C   . TYR A 1 231 ? 15.794  26.517  14.546  1.00 31.12  ? 231 TYR A C   1 
ATOM   1865  O O   . TYR A 1 231 ? 14.629  26.336  14.906  1.00 29.57  ? 231 TYR A O   1 
ATOM   1866  C CB  . TYR A 1 231 ? 17.745  26.473  16.192  1.00 32.73  ? 231 TYR A CB  1 
ATOM   1867  C CG  . TYR A 1 231 ? 16.894  26.964  17.350  1.00 32.31  ? 231 TYR A CG  1 
ATOM   1868  C CD1 . TYR A 1 231 ? 15.975  27.983  17.157  1.00 34.93  ? 231 TYR A CD1 1 
ATOM   1869  C CD2 . TYR A 1 231 ? 17.038  26.449  18.633  1.00 33.42  ? 231 TYR A CD2 1 
ATOM   1870  C CE1 . TYR A 1 231 ? 15.198  28.454  18.202  1.00 41.08  ? 231 TYR A CE1 1 
ATOM   1871  C CE2 . TYR A 1 231 ? 16.279  26.927  19.692  1.00 38.80  ? 231 TYR A CE2 1 
ATOM   1872  C CZ  . TYR A 1 231 ? 15.335  27.923  19.472  1.00 43.22  ? 231 TYR A CZ  1 
ATOM   1873  O OH  . TYR A 1 231 ? 14.539  28.444  20.460  1.00 41.93  ? 231 TYR A OH  1 
ATOM   1874  N N   . MET A 1 232 ? 16.142  27.408  13.612  1.00 29.20  ? 232 MET A N   1 
ATOM   1875  C CA  . MET A 1 232 ? 15.189  28.295  12.954  1.00 29.06  ? 232 MET A CA  1 
ATOM   1876  C C   . MET A 1 232 ? 14.215  27.502  12.081  1.00 29.14  ? 232 MET A C   1 
ATOM   1877  O O   . MET A 1 232 ? 13.032  27.808  11.978  1.00 26.48  ? 232 MET A O   1 
ATOM   1878  C CB  . MET A 1 232 ? 15.933  29.313  12.086  1.00 28.18  ? 232 MET A CB  1 
ATOM   1879  C CG  . MET A 1 232 ? 16.804  30.280  12.899  1.00 30.50  ? 232 MET A CG  1 
ATOM   1880  S SD  . MET A 1 232 ? 15.846  31.271  14.068  1.00 31.98  ? 232 MET A SD  1 
ATOM   1881  C CE  . MET A 1 232 ? 16.828  31.617  15.532  1.00 32.54  ? 232 MET A CE  1 
ATOM   1882  N N   . PHE A 1 233 ? 14.716  26.443  11.460  1.00 30.60  ? 233 PHE A N   1 
ATOM   1883  C CA  . PHE A 1 233 ? 13.857  25.607  10.650  1.00 31.08  ? 233 PHE A CA  1 
ATOM   1884  C C   . PHE A 1 233 ? 12.799  24.979  11.552  1.00 27.98  ? 233 PHE A C   1 
ATOM   1885  O O   . PHE A 1 233 ? 11.614  25.055  11.236  1.00 24.99  ? 233 PHE A O   1 
ATOM   1886  C CB  . PHE A 1 233 ? 14.779  24.642  9.902   1.00 32.98  ? 233 PHE A CB  1 
ATOM   1887  C CG  . PHE A 1 233 ? 14.056  23.463  9.281   1.00 33.91  ? 233 PHE A CG  1 
ATOM   1888  C CD1 . PHE A 1 233 ? 13.409  23.592  8.062   1.00 34.23  ? 233 PHE A CD1 1 
ATOM   1889  C CD2 . PHE A 1 233 ? 14.007  22.241  9.944   1.00 36.05  ? 233 PHE A CD2 1 
ATOM   1890  C CE1 . PHE A 1 233 ? 12.746  22.516  7.502   1.00 36.40  ? 233 PHE A CE1 1 
ATOM   1891  C CE2 . PHE A 1 233 ? 13.322  21.176  9.392   1.00 35.82  ? 233 PHE A CE2 1 
ATOM   1892  C CZ  . PHE A 1 233 ? 12.710  21.311  8.166   1.00 37.51  ? 233 PHE A CZ  1 
ATOM   1893  N N   . LEU A 1 234 ? 13.250  24.419  12.691  1.00 29.85  ? 234 LEU A N   1 
ATOM   1894  C CA  . LEU A 1 234 ? 12.464  23.493  13.499  1.00 30.64  ? 234 LEU A CA  1 
ATOM   1895  C C   . LEU A 1 234 ? 11.337  24.191  14.272  1.00 31.21  ? 234 LEU A C   1 
ATOM   1896  O O   . LEU A 1 234 ? 10.288  23.581  14.529  1.00 29.07  ? 234 LEU A O   1 
ATOM   1897  C CB  . LEU A 1 234 ? 13.390  22.755  14.461  1.00 32.51  ? 234 LEU A CB  1 
ATOM   1898  C CG  . LEU A 1 234 ? 14.264  21.630  13.898  1.00 33.65  ? 234 LEU A CG  1 
ATOM   1899  C CD1 . LEU A 1 234 ? 15.127  21.140  15.043  1.00 33.66  ? 234 LEU A CD1 1 
ATOM   1900  C CD2 . LEU A 1 234 ? 13.492  20.463  13.300  1.00 34.13  ? 234 LEU A CD2 1 
ATOM   1901  N N   . HIS A 1 235 ? 11.571  25.453  14.664  1.00 29.08  ? 235 HIS A N   1 
ATOM   1902  C CA  . HIS A 1 235 ? 10.662  26.186  15.534  1.00 32.88  ? 235 HIS A CA  1 
ATOM   1903  C C   . HIS A 1 235 ? 9.786   27.130  14.707  1.00 32.37  ? 235 HIS A C   1 
ATOM   1904  O O   . HIS A 1 235 ? 9.056   27.953  15.277  1.00 31.47  ? 235 HIS A O   1 
ATOM   1905  C CB  . HIS A 1 235 ? 11.438  26.978  16.605  1.00 33.84  ? 235 HIS A CB  1 
ATOM   1906  C CG  . HIS A 1 235 ? 12.175  26.128  17.597  1.00 35.59  ? 235 HIS A CG  1 
ATOM   1907  N ND1 . HIS A 1 235 ? 13.298  25.382  17.286  1.00 36.57  ? 235 HIS A ND1 1 
ATOM   1908  C CD2 . HIS A 1 235 ? 11.917  25.881  18.885  1.00 35.80  ? 235 HIS A CD2 1 
ATOM   1909  C CE1 . HIS A 1 235 ? 13.700  24.729  18.366  1.00 35.33  ? 235 HIS A CE1 1 
ATOM   1910  N NE2 . HIS A 1 235 ? 12.884  25.028  19.349  1.00 37.08  ? 235 HIS A NE2 1 
ATOM   1911  N N   . SER A 1 236 ? 9.867   26.986  13.373  1.00 29.16  ? 236 SER A N   1 
ATOM   1912  C CA  . SER A 1 236 ? 9.305   27.951  12.440  1.00 31.47  ? 236 SER A CA  1 
ATOM   1913  C C   . SER A 1 236 ? 7.780   28.001  12.558  1.00 33.17  ? 236 SER A C   1 
ATOM   1914  O O   . SER A 1 236 ? 7.190   29.079  12.495  1.00 31.96  ? 236 SER A O   1 
ATOM   1915  C CB  . SER A 1 236 ? 9.724   27.638  11.015  1.00 31.25  ? 236 SER A CB  1 
ATOM   1916  O OG  . SER A 1 236 ? 9.355   26.307  10.694  1.00 29.42  ? 236 SER A OG  1 
ATOM   1917  N N   . ASP A 1 237 ? 7.144   26.833  12.727  1.00 30.62  ? 237 ASP A N   1 
ATOM   1918  C CA  . ASP A 1 237 ? 5.708   26.758  12.560  1.00 31.58  ? 237 ASP A CA  1 
ATOM   1919  C C   . ASP A 1 237 ? 5.181   25.467  13.176  1.00 33.12  ? 237 ASP A C   1 
ATOM   1920  O O   . ASP A 1 237 ? 5.804   24.413  13.042  1.00 32.78  ? 237 ASP A O   1 
ATOM   1921  C CB  . ASP A 1 237 ? 5.356   26.839  11.081  1.00 30.32  ? 237 ASP A CB  1 
ATOM   1922  C CG  . ASP A 1 237 ? 3.921   27.224  10.756  1.00 30.52  ? 237 ASP A CG  1 
ATOM   1923  O OD1 . ASP A 1 237 ? 3.455   28.264  11.290  1.00 30.39  ? 237 ASP A OD1 1 
ATOM   1924  O OD2 . ASP A 1 237 ? 3.298   26.520  9.929   1.00 30.32  ? 237 ASP A OD2 1 
ATOM   1925  N N   . HIS A 1 238 ? 4.006   25.557  13.804  1.00 32.87  ? 238 HIS A N   1 
ATOM   1926  C CA  . HIS A 1 238 ? 3.351   24.375  14.347  1.00 36.79  ? 238 HIS A CA  1 
ATOM   1927  C C   . HIS A 1 238 ? 1.832   24.583  14.318  1.00 36.73  ? 238 HIS A C   1 
ATOM   1928  O O   . HIS A 1 238 ? 1.207   24.712  15.367  1.00 32.34  ? 238 HIS A O   1 
ATOM   1929  C CB  . HIS A 1 238 ? 3.936   24.096  15.737  1.00 38.94  ? 238 HIS A CB  1 
ATOM   1930  C CG  . HIS A 1 238 ? 3.902   22.672  16.193  1.00 36.44  ? 238 HIS A CG  1 
ATOM   1931  N ND1 . HIS A 1 238 ? 3.110   22.226  17.230  1.00 36.52  ? 238 HIS A ND1 1 
ATOM   1932  C CD2 . HIS A 1 238 ? 4.613   21.620  15.788  1.00 34.29  ? 238 HIS A CD2 1 
ATOM   1933  C CE1 . HIS A 1 238 ? 3.323   20.930  17.405  1.00 36.83  ? 238 HIS A CE1 1 
ATOM   1934  N NE2 . HIS A 1 238 ? 4.222   20.537  16.527  1.00 36.71  ? 238 HIS A NE2 1 
ATOM   1935  N N   . GLU A 1 239 ? 1.260   24.661  13.098  1.00 36.11  ? 239 GLU A N   1 
ATOM   1936  C CA  . GLU A 1 239 ? -0.165  24.893  12.888  1.00 36.50  ? 239 GLU A CA  1 
ATOM   1937  C C   . GLU A 1 239 ? -0.557  26.327  13.246  1.00 35.86  ? 239 GLU A C   1 
ATOM   1938  O O   . GLU A 1 239 ? 0.287   27.133  13.663  1.00 31.91  ? 239 GLU A O   1 
ATOM   1939  C CB  . GLU A 1 239 ? -1.025  23.962  13.746  1.00 38.49  ? 239 GLU A CB  1 
ATOM   1940  C CG  . GLU A 1 239 ? -1.224  22.586  13.136  1.00 41.16  ? 239 GLU A CG  1 
ATOM   1941  C CD  . GLU A 1 239 ? -2.360  21.803  13.770  1.00 41.85  ? 239 GLU A CD  1 
ATOM   1942  O OE1 . GLU A 1 239 ? -2.613  20.707  13.231  1.00 38.73  ? 239 GLU A OE1 1 
ATOM   1943  O OE2 . GLU A 1 239 ? -2.996  22.256  14.747  1.00 41.53  ? 239 GLU A OE2 1 
ATOM   1944  N N   . GLY A 1 240 ? -1.873  26.590  13.127  1.00 33.99  ? 240 GLY A N   1 
ATOM   1945  C CA  . GLY A 1 240 ? -2.481  27.870  13.463  1.00 34.54  ? 240 GLY A CA  1 
ATOM   1946  C C   . GLY A 1 240 ? -2.972  28.013  14.912  1.00 35.79  ? 240 GLY A C   1 
ATOM   1947  O O   . GLY A 1 240 ? -3.321  29.121  15.309  1.00 37.51  ? 240 GLY A O   1 
ATOM   1948  N N   . GLY A 1 241 ? -2.967  26.938  15.715  1.00 34.92  ? 241 GLY A N   1 
ATOM   1949  C CA  . GLY A 1 241 ? -3.729  26.905  16.959  1.00 34.60  ? 241 GLY A CA  1 
ATOM   1950  C C   . GLY A 1 241 ? -2.939  27.242  18.228  1.00 34.64  ? 241 GLY A C   1 
ATOM   1951  O O   . GLY A 1 241 ? -3.542  27.547  19.264  1.00 35.45  ? 241 GLY A O   1 
ATOM   1952  N N   . ASN A 1 242 ? -1.599  27.180  18.165  1.00 33.59  ? 242 ASN A N   1 
ATOM   1953  C CA  . ASN A 1 242 ? -0.767  27.488  19.322  1.00 32.07  ? 242 ASN A CA  1 
ATOM   1954  C C   . ASN A 1 242 ? -0.950  28.970  19.672  1.00 30.70  ? 242 ASN A C   1 
ATOM   1955  O O   . ASN A 1 242 ? -1.357  29.772  18.827  1.00 29.65  ? 242 ASN A O   1 
ATOM   1956  C CB  . ASN A 1 242 ? 0.679   27.039  19.096  1.00 32.68  ? 242 ASN A CB  1 
ATOM   1957  C CG  . ASN A 1 242 ? 1.377   27.804  17.997  1.00 33.73  ? 242 ASN A CG  1 
ATOM   1958  O OD1 . ASN A 1 242 ? 1.689   28.990  18.155  1.00 34.92  ? 242 ASN A OD1 1 
ATOM   1959  N ND2 . ASN A 1 242 ? 1.648   27.151  16.878  1.00 38.66  ? 242 ASN A ND2 1 
ATOM   1960  N N   . VAL A 1 243 ? -0.638  29.338  20.919  1.00 29.64  ? 243 VAL A N   1 
ATOM   1961  C CA  . VAL A 1 243 ? -0.940  30.675  21.417  1.00 30.10  ? 243 VAL A CA  1 
ATOM   1962  C C   . VAL A 1 243 ? -0.292  31.746  20.544  1.00 30.32  ? 243 VAL A C   1 
ATOM   1963  O O   . VAL A 1 243 ? -0.935  32.755  20.257  1.00 33.70  ? 243 VAL A O   1 
ATOM   1964  C CB  . VAL A 1 243 ? -0.574  30.873  22.904  1.00 32.15  ? 243 VAL A CB  1 
ATOM   1965  C CG1 . VAL A 1 243 ? -0.882  32.288  23.414  1.00 31.35  ? 243 VAL A CG1 1 
ATOM   1966  C CG2 . VAL A 1 243 ? -1.278  29.857  23.791  1.00 33.59  ? 243 VAL A CG2 1 
ATOM   1967  N N   . SER A 1 244 ? 0.975   31.562  20.146  1.00 32.73  ? 244 SER A N   1 
ATOM   1968  C CA  . SER A 1 244 ? 1.682   32.619  19.443  1.00 33.23  ? 244 SER A CA  1 
ATOM   1969  C C   . SER A 1 244 ? 1.100   32.752  18.044  1.00 34.02  ? 244 SER A C   1 
ATOM   1970  O O   . SER A 1 244 ? 0.721   33.856  17.670  1.00 39.30  ? 244 SER A O   1 
ATOM   1971  C CB  . SER A 1 244 ? 3.213   32.471  19.439  1.00 34.97  ? 244 SER A CB  1 
ATOM   1972  O OG  . SER A 1 244 ? 3.707   31.254  18.888  1.00 32.17  ? 244 SER A OG  1 
ATOM   1973  N N   . ALA A 1 245 ? 0.977   31.624  17.318  1.00 34.28  ? 245 ALA A N   1 
ATOM   1974  C CA  . ALA A 1 245 ? 0.402   31.601  15.971  1.00 37.50  ? 245 ALA A CA  1 
ATOM   1975  C C   . ALA A 1 245 ? -1.030  32.164  15.955  1.00 35.65  ? 245 ALA A C   1 
ATOM   1976  O O   . ALA A 1 245 ? -1.388  32.964  15.088  1.00 37.82  ? 245 ALA A O   1 
ATOM   1977  C CB  . ALA A 1 245 ? 0.442   30.181  15.414  1.00 38.09  ? 245 ALA A CB  1 
ATOM   1978  N N   . HIS A 1 246 ? -1.828  31.765  16.948  1.00 29.59  ? 246 HIS A N   1 
ATOM   1979  C CA  . HIS A 1 246 ? -3.226  32.126  17.031  1.00 30.23  ? 246 HIS A CA  1 
ATOM   1980  C C   . HIS A 1 246 ? -3.370  33.607  17.369  1.00 30.78  ? 246 HIS A C   1 
ATOM   1981  O O   . HIS A 1 246 ? -4.198  34.279  16.761  1.00 31.96  ? 246 HIS A O   1 
ATOM   1982  C CB  . HIS A 1 246 ? -3.927  31.208  18.033  1.00 32.08  ? 246 HIS A CB  1 
ATOM   1983  C CG  . HIS A 1 246 ? -5.379  31.491  18.185  1.00 33.85  ? 246 HIS A CG  1 
ATOM   1984  N ND1 . HIS A 1 246 ? -6.101  31.057  19.276  1.00 32.65  ? 246 HIS A ND1 1 
ATOM   1985  C CD2 . HIS A 1 246 ? -6.232  32.150  17.392  1.00 30.91  ? 246 HIS A CD2 1 
ATOM   1986  C CE1 . HIS A 1 246 ? -7.359  31.437  19.118  1.00 32.87  ? 246 HIS A CE1 1 
ATOM   1987  N NE2 . HIS A 1 246 ? -7.460  32.085  17.976  1.00 31.98  ? 246 HIS A NE2 1 
ATOM   1988  N N   . THR A 1 247 ? -2.572  34.118  18.323  1.00 30.62  ? 247 THR A N   1 
ATOM   1989  C CA  . THR A 1 247 ? -2.594  35.540  18.659  1.00 28.23  ? 247 THR A CA  1 
ATOM   1990  C C   . THR A 1 247 ? -2.256  36.348  17.405  1.00 29.21  ? 247 THR A C   1 
ATOM   1991  O O   . THR A 1 247 ? -2.912  37.345  17.109  1.00 32.67  ? 247 THR A O   1 
ATOM   1992  C CB  . THR A 1 247 ? -1.634  35.835  19.807  1.00 27.43  ? 247 THR A CB  1 
ATOM   1993  O OG1 . THR A 1 247 ? -2.028  35.077  20.948  1.00 23.15  ? 247 THR A OG1 1 
ATOM   1994  C CG2 . THR A 1 247 ? -1.621  37.305  20.179  1.00 25.99  ? 247 THR A CG2 1 
ATOM   1995  N N   . ASN A 1 248 ? -1.312  35.841  16.606  1.00 30.54  ? 248 ASN A N   1 
ATOM   1996  C CA  . ASN A 1 248 ? -0.952  36.475  15.343  1.00 31.55  ? 248 ASN A CA  1 
ATOM   1997  C C   . ASN A 1 248 ? -2.172  36.552  14.428  1.00 31.78  ? 248 ASN A C   1 
ATOM   1998  O O   . ASN A 1 248 ? -2.445  37.600  13.823  1.00 28.81  ? 248 ASN A O   1 
ATOM   1999  C CB  . ASN A 1 248 ? 0.246   35.790  14.690  1.00 30.06  ? 248 ASN A CB  1 
ATOM   2000  C CG  . ASN A 1 248 ? 0.634   36.414  13.362  1.00 29.86  ? 248 ASN A CG  1 
ATOM   2001  O OD1 . ASN A 1 248 ? 0.749   35.701  12.356  1.00 31.05  ? 248 ASN A OD1 1 
ATOM   2002  N ND2 . ASN A 1 248 ? 0.855   37.719  13.324  1.00 26.77  ? 248 ASN A ND2 1 
ATOM   2003  N N   . LEU A 1 249 ? -2.914  35.438  14.345  1.00 30.74  ? 249 LEU A N   1 
ATOM   2004  C CA  . LEU A 1 249 ? -4.027  35.367  13.407  1.00 31.45  ? 249 LEU A CA  1 
ATOM   2005  C C   . LEU A 1 249 ? -5.152  36.293  13.857  1.00 28.92  ? 249 LEU A C   1 
ATOM   2006  O O   . LEU A 1 249 ? -5.796  36.941  13.037  1.00 26.43  ? 249 LEU A O   1 
ATOM   2007  C CB  . LEU A 1 249 ? -4.522  33.932  13.243  1.00 31.34  ? 249 LEU A CB  1 
ATOM   2008  C CG  . LEU A 1 249 ? -3.595  32.988  12.465  1.00 31.88  ? 249 LEU A CG  1 
ATOM   2009  C CD1 . LEU A 1 249 ? -4.248  31.615  12.369  1.00 31.83  ? 249 LEU A CD1 1 
ATOM   2010  C CD2 . LEU A 1 249 ? -3.249  33.526  11.084  1.00 31.39  ? 249 LEU A CD2 1 
ATOM   2011  N N   . LEU A 1 250 ? -5.369  36.299  15.176  1.00 27.76  ? 250 LEU A N   1 
ATOM   2012  C CA  . LEU A 1 250 ? -6.438  37.047  15.805  1.00 26.41  ? 250 LEU A CA  1 
ATOM   2013  C C   . LEU A 1 250 ? -6.219  38.545  15.578  1.00 25.66  ? 250 LEU A C   1 
ATOM   2014  O O   . LEU A 1 250 ? -7.111  39.240  15.099  1.00 25.03  ? 250 LEU A O   1 
ATOM   2015  C CB  . LEU A 1 250 ? -6.458  36.624  17.277  1.00 25.93  ? 250 LEU A CB  1 
ATOM   2016  C CG  . LEU A 1 250 ? -7.446  37.327  18.208  1.00 27.47  ? 250 LEU A CG  1 
ATOM   2017  C CD1 . LEU A 1 250 ? -8.859  37.283  17.657  1.00 27.68  ? 250 LEU A CD1 1 
ATOM   2018  C CD2 . LEU A 1 250 ? -7.373  36.692  19.593  1.00 27.92  ? 250 LEU A CD2 1 
ATOM   2019  N N   . VAL A 1 251 ? -5.014  39.043  15.860  1.00 25.30  ? 251 VAL A N   1 
ATOM   2020  C CA  . VAL A 1 251 ? -4.818  40.470  15.736  1.00 26.56  ? 251 VAL A CA  1 
ATOM   2021  C C   . VAL A 1 251 ? -4.779  40.801  14.249  1.00 27.91  ? 251 VAL A C   1 
ATOM   2022  O O   . VAL A 1 251 ? -5.220  41.860  13.806  1.00 26.18  ? 251 VAL A O   1 
ATOM   2023  C CB  . VAL A 1 251 ? -3.549  40.876  16.509  1.00 27.52  ? 251 VAL A CB  1 
ATOM   2024  C CG1 . VAL A 1 251 ? -3.170  42.345  16.322  1.00 26.75  ? 251 VAL A CG1 1 
ATOM   2025  C CG2 . VAL A 1 251 ? -3.713  40.573  17.991  1.00 26.48  ? 251 VAL A CG2 1 
ATOM   2026  N N   . ASN A 1 252 ? -4.266  39.863  13.457  1.00 29.75  ? 252 ASN A N   1 
ATOM   2027  C CA  . ASN A 1 252 ? -4.228  40.083  12.020  1.00 32.97  ? 252 ASN A CA  1 
ATOM   2028  C C   . ASN A 1 252 ? -5.646  40.258  11.477  1.00 32.48  ? 252 ASN A C   1 
ATOM   2029  O O   . ASN A 1 252 ? -5.872  41.121  10.648  1.00 35.78  ? 252 ASN A O   1 
ATOM   2030  C CB  . ASN A 1 252 ? -3.451  38.975  11.325  1.00 34.21  ? 252 ASN A CB  1 
ATOM   2031  C CG  . ASN A 1 252 ? -3.584  39.036  9.828   1.00 32.02  ? 252 ASN A CG  1 
ATOM   2032  O OD1 . ASN A 1 252 ? -4.505  38.445  9.263   1.00 34.17  ? 252 ASN A OD1 1 
ATOM   2033  N ND2 . ASN A 1 252 ? -2.656  39.710  9.173   1.00 34.92  ? 252 ASN A ND2 1 
ATOM   2034  N N   . SER A 1 253 ? -6.601  39.452  11.955  1.00 32.95  ? 253 SER A N   1 
ATOM   2035  C CA  . SER A 1 253 ? -7.986  39.467  11.483  1.00 32.14  ? 253 SER A CA  1 
ATOM   2036  C C   . SER A 1 253 ? -8.677  40.839  11.573  1.00 30.04  ? 253 SER A C   1 
ATOM   2037  O O   . SER A 1 253 ? -9.659  41.064  10.869  1.00 28.87  ? 253 SER A O   1 
ATOM   2038  C CB  . SER A 1 253 ? -8.794  38.442  12.243  1.00 33.51  ? 253 SER A CB  1 
ATOM   2039  O OG  . SER A 1 253 ? -9.038  38.855  13.584  1.00 31.97  ? 253 SER A OG  1 
ATOM   2040  N N   . ALA A 1 254 ? -8.217  41.726  12.470  1.00 29.99  ? 254 ALA A N   1 
ATOM   2041  C CA  . ALA A 1 254 ? -8.781  43.059  12.624  1.00 28.03  ? 254 ALA A CA  1 
ATOM   2042  C C   . ALA A 1 254 ? -8.142  44.035  11.650  1.00 28.55  ? 254 ALA A C   1 
ATOM   2043  O O   . ALA A 1 254 ? -8.435  45.235  11.709  1.00 32.38  ? 254 ALA A O   1 
ATOM   2044  C CB  . ALA A 1 254 ? -8.583  43.549  14.035  1.00 28.85  ? 254 ALA A CB  1 
ATOM   2045  N N   . TYR A 1 255 ? -7.282  43.509  10.769  1.00 26.91  ? 255 TYR A N   1 
ATOM   2046  C CA  . TYR A 1 255 ? -6.467  44.288  9.849   1.00 27.76  ? 255 TYR A CA  1 
ATOM   2047  C C   . TYR A 1 255 ? -5.370  45.047  10.599  1.00 29.77  ? 255 TYR A C   1 
ATOM   2048  O O   . TYR A 1 255 ? -4.938  46.102  10.147  1.00 32.71  ? 255 TYR A O   1 
ATOM   2049  C CB  . TYR A 1 255 ? -7.266  45.252  8.962   1.00 28.84  ? 255 TYR A CB  1 
ATOM   2050  C CG  . TYR A 1 255 ? -8.141  44.650  7.875   1.00 33.09  ? 255 TYR A CG  1 
ATOM   2051  C CD1 . TYR A 1 255 ? -8.135  43.291  7.566   1.00 37.79  ? 255 TYR A CD1 1 
ATOM   2052  C CD2 . TYR A 1 255 ? -8.979  45.461  7.140   1.00 36.79  ? 255 TYR A CD2 1 
ATOM   2053  C CE1 . TYR A 1 255 ? -8.957  42.755  6.586   1.00 37.83  ? 255 TYR A CE1 1 
ATOM   2054  C CE2 . TYR A 1 255 ? -9.775  44.948  6.127   1.00 40.62  ? 255 TYR A CE2 1 
ATOM   2055  C CZ  . TYR A 1 255 ? -9.768  43.594  5.837   1.00 43.46  ? 255 TYR A CZ  1 
ATOM   2056  O OH  . TYR A 1 255 ? -10.580 43.139  4.818   1.00 40.40  ? 255 TYR A OH  1 
ATOM   2057  N N   . SER A 1 256 ? -4.911  44.536  11.746  1.00 31.92  ? 256 SER A N   1 
ATOM   2058  C CA  . SER A 1 256 ? -3.696  45.087  12.333  1.00 34.11  ? 256 SER A CA  1 
ATOM   2059  C C   . SER A 1 256 ? -2.497  44.494  11.598  1.00 31.40  ? 256 SER A C   1 
ATOM   2060  O O   . SER A 1 256 ? -2.518  43.312  11.262  1.00 33.96  ? 256 SER A O   1 
ATOM   2061  C CB  . SER A 1 256 ? -3.583  44.828  13.815  1.00 34.50  ? 256 SER A CB  1 
ATOM   2062  O OG  . SER A 1 256 ? -4.526  45.566  14.582  1.00 32.03  ? 256 SER A OG  1 
ATOM   2063  N N   . ASP A 1 257 ? -1.475  45.328  11.369  1.00 29.51  ? 257 ASP A N   1 
ATOM   2064  C CA  . ASP A 1 257 ? -0.300  44.979  10.581  1.00 28.11  ? 257 ASP A CA  1 
ATOM   2065  C C   . ASP A 1 257 ? 0.599   43.992  11.325  1.00 25.36  ? 257 ASP A C   1 
ATOM   2066  O O   . ASP A 1 257 ? 0.395   43.701  12.481  1.00 23.49  ? 257 ASP A O   1 
ATOM   2067  C CB  . ASP A 1 257 ? 0.466   46.227  10.173  1.00 26.85  ? 257 ASP A CB  1 
ATOM   2068  C CG  . ASP A 1 257 ? 1.040   47.025  11.329  1.00 27.24  ? 257 ASP A CG  1 
ATOM   2069  O OD1 . ASP A 1 257 ? 1.892   46.469  12.057  1.00 27.15  ? 257 ASP A OD1 1 
ATOM   2070  O OD2 . ASP A 1 257 ? 0.640   48.198  11.466  1.00 24.55  ? 257 ASP A OD2 1 
ATOM   2071  N N   . ILE A 1 258 ? 1.622   43.479  10.652  1.00 26.59  ? 258 ILE A N   1 
ATOM   2072  C CA  . ILE A 1 258 ? 2.426   42.397  11.197  1.00 27.89  ? 258 ILE A CA  1 
ATOM   2073  C C   . ILE A 1 258 ? 3.231   42.829  12.429  1.00 29.04  ? 258 ILE A C   1 
ATOM   2074  O O   . ILE A 1 258 ? 3.538   41.996  13.281  1.00 30.49  ? 258 ILE A O   1 
ATOM   2075  C CB  . ILE A 1 258 ? 3.354   41.819  10.119  1.00 29.61  ? 258 ILE A CB  1 
ATOM   2076  C CG1 . ILE A 1 258 ? 3.909   40.481  10.538  1.00 29.00  ? 258 ILE A CG1 1 
ATOM   2077  C CG2 . ILE A 1 258 ? 4.469   42.803  9.749   1.00 31.84  ? 258 ILE A CG2 1 
ATOM   2078  C CD1 . ILE A 1 258 ? 2.909   39.359  10.426  1.00 30.47  ? 258 ILE A CD1 1 
ATOM   2079  N N   . TYR A 1 259 ? 3.600   44.111  12.534  1.00 28.82  ? 259 TYR A N   1 
ATOM   2080  C CA  . TYR A 1 259 ? 4.345   44.567  13.702  1.00 26.37  ? 259 TYR A CA  1 
ATOM   2081  C C   . TYR A 1 259 ? 3.482   44.405  14.956  1.00 27.61  ? 259 TYR A C   1 
ATOM   2082  O O   . TYR A 1 259 ? 3.977   44.046  16.033  1.00 30.79  ? 259 TYR A O   1 
ATOM   2083  C CB  . TYR A 1 259 ? 4.837   45.996  13.476  1.00 23.70  ? 259 TYR A CB  1 
ATOM   2084  C CG  . TYR A 1 259 ? 5.814   46.107  12.320  1.00 26.04  ? 259 TYR A CG  1 
ATOM   2085  C CD1 . TYR A 1 259 ? 7.166   45.844  12.503  1.00 28.91  ? 259 TYR A CD1 1 
ATOM   2086  C CD2 . TYR A 1 259 ? 5.394   46.432  11.039  1.00 26.70  ? 259 TYR A CD2 1 
ATOM   2087  C CE1 . TYR A 1 259 ? 8.074   45.938  11.461  1.00 28.69  ? 259 TYR A CE1 1 
ATOM   2088  C CE2 . TYR A 1 259 ? 6.290   46.516  9.984   1.00 25.39  ? 259 TYR A CE2 1 
ATOM   2089  C CZ  . TYR A 1 259 ? 7.638   46.274  10.195  1.00 27.62  ? 259 TYR A CZ  1 
ATOM   2090  O OH  . TYR A 1 259 ? 8.564   46.308  9.176   1.00 25.76  ? 259 TYR A OH  1 
ATOM   2091  N N   . ARG A 1 260 ? 2.184   44.681  14.799  1.00 25.66  ? 260 ARG A N   1 
ATOM   2092  C CA  . ARG A 1 260 ? 1.237   44.658  15.899  1.00 24.09  ? 260 ARG A CA  1 
ATOM   2093  C C   . ARG A 1 260 ? 0.835   43.223  16.194  1.00 23.02  ? 260 ARG A C   1 
ATOM   2094  O O   . ARG A 1 260 ? 0.692   42.872  17.359  1.00 22.38  ? 260 ARG A O   1 
ATOM   2095  C CB  . ARG A 1 260 ? -0.010  45.475  15.544  1.00 25.73  ? 260 ARG A CB  1 
ATOM   2096  C CG  . ARG A 1 260 ? 0.192   46.944  15.880  1.00 25.84  ? 260 ARG A CG  1 
ATOM   2097  C CD  . ARG A 1 260 ? -0.740  47.847  15.135  1.00 25.97  ? 260 ARG A CD  1 
ATOM   2098  N NE  . ARG A 1 260 ? -0.745  49.193  15.704  1.00 26.35  ? 260 ARG A NE  1 
ATOM   2099  C CZ  . ARG A 1 260 ? -1.393  50.215  15.175  1.00 22.98  ? 260 ARG A CZ  1 
ATOM   2100  N NH1 . ARG A 1 260 ? -2.057  50.044  14.071  1.00 23.11  ? 260 ARG A NH1 1 
ATOM   2101  N NH2 . ARG A 1 260 ? -1.415  51.384  15.765  1.00 23.62  ? 260 ARG A NH2 1 
ATOM   2102  N N   . SER A 1 261 ? 0.671   42.421  15.132  1.00 22.49  ? 261 SER A N   1 
ATOM   2103  C CA  . SER A 1 261 ? 0.168   41.064  15.249  1.00 23.66  ? 261 SER A CA  1 
ATOM   2104  C C   . SER A 1 261 ? 1.254   40.137  15.768  1.00 24.27  ? 261 SER A C   1 
ATOM   2105  O O   . SER A 1 261 ? 0.970   39.173  16.478  1.00 28.10  ? 261 SER A O   1 
ATOM   2106  C CB  . SER A 1 261 ? -0.425  40.556  13.955  1.00 25.24  ? 261 SER A CB  1 
ATOM   2107  O OG  . SER A 1 261 ? 0.539   40.263  12.944  1.00 26.65  ? 261 SER A OG  1 
ATOM   2108  N N   . PHE A 1 262 ? 2.497   40.421  15.404  1.00 25.10  ? 262 PHE A N   1 
ATOM   2109  C CA  . PHE A 1 262 ? 3.591   39.556  15.813  1.00 25.66  ? 262 PHE A CA  1 
ATOM   2110  C C   . PHE A 1 262 ? 4.119   39.950  17.198  1.00 25.88  ? 262 PHE A C   1 
ATOM   2111  O O   . PHE A 1 262 ? 4.405   39.058  18.007  1.00 24.67  ? 262 PHE A O   1 
ATOM   2112  C CB  . PHE A 1 262 ? 4.659   39.569  14.729  1.00 26.93  ? 262 PHE A CB  1 
ATOM   2113  C CG  . PHE A 1 262 ? 5.725   38.548  15.045  1.00 27.24  ? 262 PHE A CG  1 
ATOM   2114  C CD1 . PHE A 1 262 ? 5.414   37.194  15.038  1.00 28.16  ? 262 PHE A CD1 1 
ATOM   2115  C CD2 . PHE A 1 262 ? 7.016   38.950  15.364  1.00 27.35  ? 262 PHE A CD2 1 
ATOM   2116  C CE1 . PHE A 1 262 ? 6.385   36.251  15.365  1.00 30.85  ? 262 PHE A CE1 1 
ATOM   2117  C CE2 . PHE A 1 262 ? 7.981   38.009  15.704  1.00 29.64  ? 262 PHE A CE2 1 
ATOM   2118  C CZ  . PHE A 1 262 ? 7.665   36.657  15.701  1.00 29.37  ? 262 PHE A CZ  1 
ATOM   2119  N N   . SER A 1 263 ? 4.244   41.262  17.488  1.00 21.99  ? 263 SER A N   1 
ATOM   2120  C CA  . SER A 1 263 ? 4.618   41.664  18.824  1.00 21.51  ? 263 SER A CA  1 
ATOM   2121  C C   . SER A 1 263 ? 3.598   41.086  19.805  1.00 25.89  ? 263 SER A C   1 
ATOM   2122  O O   . SER A 1 263 ? 3.982   40.560  20.862  1.00 22.84  ? 263 SER A O   1 
ATOM   2123  C CB  . SER A 1 263 ? 4.746   43.156  18.958  1.00 22.21  ? 263 SER A CB  1 
ATOM   2124  O OG  . SER A 1 263 ? 3.585   43.850  18.539  1.00 20.92  ? 263 SER A OG  1 
ATOM   2125  N N   . ALA A 1 264 ? 2.301   41.147  19.424  1.00 23.59  ? 264 ALA A N   1 
ATOM   2126  C CA  . ALA A 1 264 ? 1.255   40.597  20.259  1.00 23.81  ? 264 ALA A CA  1 
ATOM   2127  C C   . ALA A 1 264 ? 1.495   39.113  20.452  1.00 24.17  ? 264 ALA A C   1 
ATOM   2128  O O   . ALA A 1 264 ? 1.361   38.598  21.570  1.00 24.69  ? 264 ALA A O   1 
ATOM   2129  C CB  . ALA A 1 264 ? -0.108  40.829  19.673  1.00 27.09  ? 264 ALA A CB  1 
ATOM   2130  N N   . ALA A 1 265 ? 1.845   38.448  19.356  1.00 24.17  ? 265 ALA A N   1 
ATOM   2131  C CA  . ALA A 1 265 ? 2.182   37.034  19.405  1.00 25.13  ? 265 ALA A CA  1 
ATOM   2132  C C   . ALA A 1 265 ? 3.368   36.782  20.337  1.00 27.38  ? 265 ALA A C   1 
ATOM   2133  O O   . ALA A 1 265 ? 3.374   35.780  21.065  1.00 30.31  ? 265 ALA A O   1 
ATOM   2134  C CB  . ALA A 1 265 ? 2.470   36.534  18.019  1.00 25.71  ? 265 ALA A CB  1 
ATOM   2135  N N   . MET A 1 266 ? 4.364   37.681  20.330  1.00 24.45  ? 266 MET A N   1 
ATOM   2136  C CA  . MET A 1 266 ? 5.547   37.481  21.153  1.00 25.29  ? 266 MET A CA  1 
ATOM   2137  C C   . MET A 1 266 ? 5.177   37.625  22.630  1.00 27.67  ? 266 MET A C   1 
ATOM   2138  O O   . MET A 1 266 ? 5.730   36.947  23.499  1.00 28.09  ? 266 MET A O   1 
ATOM   2139  C CB  . MET A 1 266 ? 6.684   38.438  20.758  1.00 25.52  ? 266 MET A CB  1 
ATOM   2140  C CG  . MET A 1 266 ? 7.384   38.106  19.442  1.00 24.79  ? 266 MET A CG  1 
ATOM   2141  S SD  . MET A 1 266 ? 7.949   36.395  19.292  1.00 25.96  ? 266 MET A SD  1 
ATOM   2142  C CE  . MET A 1 266 ? 6.508   35.512  18.675  1.00 28.07  ? 266 MET A CE  1 
ATOM   2143  N N   . ASN A 1 267 ? 4.198   38.487  22.911  1.00 29.23  ? 267 ASN A N   1 
ATOM   2144  C CA  . ASN A 1 267 ? 3.666   38.617  24.248  1.00 27.52  ? 267 ASN A CA  1 
ATOM   2145  C C   . ASN A 1 267 ? 3.097   37.301  24.766  1.00 28.72  ? 267 ASN A C   1 
ATOM   2146  O O   . ASN A 1 267 ? 3.213   37.009  25.949  1.00 28.21  ? 267 ASN A O   1 
ATOM   2147  C CB  . ASN A 1 267 ? 2.612   39.705  24.288  1.00 29.48  ? 267 ASN A CB  1 
ATOM   2148  C CG  . ASN A 1 267 ? 3.255   41.055  24.435  1.00 32.01  ? 267 ASN A CG  1 
ATOM   2149  O OD1 . ASN A 1 267 ? 4.491   41.180  24.339  1.00 27.74  ? 267 ASN A OD1 1 
ATOM   2150  N ND2 . ASN A 1 267 ? 2.418   42.050  24.702  1.00 33.40  ? 267 ASN A ND2 1 
ATOM   2151  N N   . GLY A 1 268 ? 2.444   36.537  23.894  1.00 31.41  ? 268 GLY A N   1 
ATOM   2152  C CA  . GLY A 1 268 ? 1.914   35.234  24.262  1.00 35.80  ? 268 GLY A CA  1 
ATOM   2153  C C   . GLY A 1 268 ? 3.019   34.185  24.357  1.00 34.97  ? 268 GLY A C   1 
ATOM   2154  O O   . GLY A 1 268 ? 3.033   33.388  25.285  1.00 31.43  ? 268 GLY A O   1 
ATOM   2155  N N   . LEU A 1 269 ? 3.943   34.199  23.386  1.00 38.18  ? 269 LEU A N   1 
ATOM   2156  C CA  . LEU A 1 269 ? 5.072   33.277  23.383  1.00 35.17  ? 269 LEU A CA  1 
ATOM   2157  C C   . LEU A 1 269 ? 5.843   33.442  24.687  1.00 31.28  ? 269 LEU A C   1 
ATOM   2158  O O   . LEU A 1 269 ? 6.398   32.457  25.164  1.00 29.37  ? 269 LEU A O   1 
ATOM   2159  C CB  . LEU A 1 269 ? 5.988   33.440  22.167  1.00 36.36  ? 269 LEU A CB  1 
ATOM   2160  C CG  . LEU A 1 269 ? 7.149   32.443  22.038  1.00 38.78  ? 269 LEU A CG  1 
ATOM   2161  C CD1 . LEU A 1 269 ? 6.673   31.019  21.765  1.00 43.52  ? 269 LEU A CD1 1 
ATOM   2162  C CD2 . LEU A 1 269 ? 8.102   32.873  20.953  1.00 36.84  ? 269 LEU A CD2 1 
ATOM   2163  N N   . ALA A 1 270 ? 5.845   34.667  25.247  1.00 27.05  ? 270 ALA A N   1 
ATOM   2164  C CA  . ALA A 1 270 ? 6.585   34.955  26.470  1.00 28.34  ? 270 ALA A CA  1 
ATOM   2165  C C   . ALA A 1 270 ? 6.004   34.217  27.676  1.00 30.53  ? 270 ALA A C   1 
ATOM   2166  O O   . ALA A 1 270 ? 6.636   34.142  28.716  1.00 34.35  ? 270 ALA A O   1 
ATOM   2167  C CB  . ALA A 1 270 ? 6.622   36.438  26.738  1.00 25.62  ? 270 ALA A CB  1 
ATOM   2168  N N   . GLY A 1 271 ? 4.792   33.675  27.536  1.00 33.69  ? 271 GLY A N   1 
ATOM   2169  C CA  . GLY A 1 271 ? 4.082   33.084  28.651  1.00 31.37  ? 271 GLY A CA  1 
ATOM   2170  C C   . GLY A 1 271 ? 4.694   31.755  29.084  1.00 27.68  ? 271 GLY A C   1 
ATOM   2171  O O   . GLY A 1 271 ? 5.075   30.940  28.252  1.00 25.58  ? 271 GLY A O   1 
ATOM   2172  N N   . PRO A 1 272 ? 4.805   31.516  30.405  1.00 25.45  ? 272 PRO A N   1 
ATOM   2173  C CA  . PRO A 1 272 ? 5.391   30.272  30.926  1.00 26.75  ? 272 PRO A CA  1 
ATOM   2174  C C   . PRO A 1 272 ? 4.961   28.951  30.293  1.00 29.63  ? 272 PRO A C   1 
ATOM   2175  O O   . PRO A 1 272 ? 5.764   28.026  30.206  1.00 31.91  ? 272 PRO A O   1 
ATOM   2176  C CB  . PRO A 1 272 ? 4.976   30.363  32.398  1.00 24.98  ? 272 PRO A CB  1 
ATOM   2177  C CG  . PRO A 1 272 ? 5.073   31.852  32.714  1.00 24.39  ? 272 PRO A CG  1 
ATOM   2178  C CD  . PRO A 1 272 ? 4.474   32.486  31.464  1.00 23.99  ? 272 PRO A CD  1 
ATOM   2179  N N   . LEU A 1 273 ? 3.705   28.857  29.845  1.00 30.40  ? 273 LEU A N   1 
ATOM   2180  C CA  . LEU A 1 273 ? 3.190   27.595  29.334  1.00 31.77  ? 273 LEU A CA  1 
ATOM   2181  C C   . LEU A 1 273 ? 3.378   27.543  27.820  1.00 33.13  ? 273 LEU A C   1 
ATOM   2182  O O   . LEU A 1 273 ? 2.979   26.575  27.184  1.00 33.62  ? 273 LEU A O   1 
ATOM   2183  C CB  . LEU A 1 273 ? 1.700   27.410  29.653  1.00 35.04  ? 273 LEU A CB  1 
ATOM   2184  C CG  . LEU A 1 273 ? 1.245   27.448  31.113  1.00 36.77  ? 273 LEU A CG  1 
ATOM   2185  C CD1 . LEU A 1 273 ? -0.248  27.760  31.196  1.00 38.60  ? 273 LEU A CD1 1 
ATOM   2186  C CD2 . LEU A 1 273 ? 1.526   26.125  31.769  1.00 39.25  ? 273 LEU A CD2 1 
ATOM   2187  N N   . HIS A 1 274 ? 3.890   28.610  27.208  1.00 36.96  ? 274 HIS A N   1 
ATOM   2188  C CA  . HIS A 1 274 ? 4.030   28.598  25.763  1.00 37.99  ? 274 HIS A CA  1 
ATOM   2189  C C   . HIS A 1 274 ? 5.493   28.550  25.349  1.00 36.92  ? 274 HIS A C   1 
ATOM   2190  O O   . HIS A 1 274 ? 5.803   27.810  24.435  1.00 47.86  ? 274 HIS A O   1 
ATOM   2191  C CB  . HIS A 1 274 ? 3.247   29.715  25.067  1.00 36.82  ? 274 HIS A CB  1 
ATOM   2192  C CG  . HIS A 1 274 ? 3.226   29.556  23.575  1.00 36.99  ? 274 HIS A CG  1 
ATOM   2193  N ND1 . HIS A 1 274 ? 3.450   28.344  22.940  1.00 34.41  ? 274 HIS A ND1 1 
ATOM   2194  C CD2 . HIS A 1 274 ? 3.029   30.471  22.595  1.00 34.65  ? 274 HIS A CD2 1 
ATOM   2195  C CE1 . HIS A 1 274 ? 3.384   28.533  21.631  1.00 34.62  ? 274 HIS A CE1 1 
ATOM   2196  N NE2 . HIS A 1 274 ? 3.159   29.822  21.397  1.00 34.88  ? 274 HIS A NE2 1 
ATOM   2197  N N   . GLY A 1 275 ? 6.386   29.315  25.978  1.00 44.73  ? 275 GLY A N   1 
ATOM   2198  C CA  . GLY A 1 275 ? 7.716   29.489  25.404  1.00 48.92  ? 275 GLY A CA  1 
ATOM   2199  C C   . GLY A 1 275 ? 8.868   29.436  26.405  1.00 48.44  ? 275 GLY A C   1 
ATOM   2200  O O   . GLY A 1 275 ? 9.950   29.925  26.087  1.00 50.03  ? 275 GLY A O   1 
ATOM   2201  N N   . LEU A 1 276 ? 8.679   28.763  27.548  1.00 52.58  ? 276 LEU A N   1 
ATOM   2202  C CA  . LEU A 1 276 ? 9.670   28.762  28.612  1.00 55.35  ? 276 LEU A CA  1 
ATOM   2203  C C   . LEU A 1 276 ? 10.218  27.353  28.862  1.00 53.69  ? 276 LEU A C   1 
ATOM   2204  O O   . LEU A 1 276 ? 11.165  27.165  29.632  1.00 63.29  ? 276 LEU A O   1 
ATOM   2205  C CB  . LEU A 1 276 ? 8.985   29.366  29.841  1.00 71.94  ? 276 LEU A CB  1 
ATOM   2206  C CG  . LEU A 1 276 ? 9.837   30.251  30.768  1.00 89.88  ? 276 LEU A CG  1 
ATOM   2207  C CD1 . LEU A 1 276 ? 9.009   31.390  31.379  1.00 89.28  ? 276 LEU A CD1 1 
ATOM   2208  C CD2 . LEU A 1 276 ? 10.526  29.459  31.894  1.00 92.63  ? 276 LEU A CD2 1 
ATOM   2209  N N   . ALA A 1 277 ? 9.654   26.341  28.209  1.00 48.00  ? 277 ALA A N   1 
ATOM   2210  C CA  . ALA A 1 277 ? 9.909   24.971  28.632  1.00 52.65  ? 277 ALA A CA  1 
ATOM   2211  C C   . ALA A 1 277 ? 11.300  24.476  28.200  1.00 58.94  ? 277 ALA A C   1 
ATOM   2212  O O   . ALA A 1 277 ? 11.805  23.497  28.776  1.00 49.13  ? 277 ALA A O   1 
ATOM   2213  C CB  . ALA A 1 277 ? 8.801   24.069  28.133  1.00 49.78  ? 277 ALA A CB  1 
ATOM   2214  N N   . ASN A 1 278 ? 11.904  25.142  27.191  1.00 58.41  ? 278 ASN A N   1 
ATOM   2215  C CA  . ASN A 1 278 ? 13.280  24.887  26.757  1.00 60.00  ? 278 ASN A CA  1 
ATOM   2216  C C   . ASN A 1 278 ? 14.232  24.969  27.959  1.00 61.83  ? 278 ASN A C   1 
ATOM   2217  O O   . ASN A 1 278 ? 15.010  24.048  28.229  1.00 44.84  ? 278 ASN A O   1 
ATOM   2218  C CB  . ASN A 1 278 ? 13.692  25.867  25.656  1.00 54.19  ? 278 ASN A CB  1 
ATOM   2219  C CG  . ASN A 1 278 ? 15.124  25.704  25.196  1.00 58.28  ? 278 ASN A CG  1 
ATOM   2220  O OD1 . ASN A 1 278 ? 15.896  24.937  25.794  1.00 62.28  ? 278 ASN A OD1 1 
ATOM   2221  N ND2 . ASN A 1 278 ? 15.506  26.418  24.142  1.00 55.42  ? 278 ASN A ND2 1 
ATOM   2222  N N   . GLN A 1 279 ? 14.119  26.093  28.679  1.00 59.85  ? 279 GLN A N   1 
ATOM   2223  C CA  . GLN A 1 279 ? 14.970  26.435  29.805  1.00 62.06  ? 279 GLN A CA  1 
ATOM   2224  C C   . GLN A 1 279 ? 14.758  25.446  30.938  1.00 61.51  ? 279 GLN A C   1 
ATOM   2225  O O   . GLN A 1 279 ? 15.697  25.002  31.602  1.00 51.37  ? 279 GLN A O   1 
ATOM   2226  C CB  . GLN A 1 279 ? 14.523  27.823  30.254  1.00 57.18  ? 279 GLN A CB  1 
ATOM   2227  C CG  . GLN A 1 279 ? 14.612  28.825  29.114  1.00 60.93  ? 279 GLN A CG  1 
ATOM   2228  C CD  . GLN A 1 279 ? 13.635  29.965  29.232  1.00 58.48  ? 279 GLN A CD  1 
ATOM   2229  O OE1 . GLN A 1 279 ? 13.621  30.713  30.223  1.00 59.92  ? 279 GLN A OE1 1 
ATOM   2230  N NE2 . GLN A 1 279 ? 12.836  30.103  28.185  1.00 50.85  ? 279 GLN A NE2 1 
ATOM   2231  N N   . GLU A 1 280 ? 13.478  25.160  31.143  1.00 61.45  ? 280 GLU A N   1 
ATOM   2232  C CA  . GLU A 1 280 ? 13.049  24.368  32.268  1.00 69.34  ? 280 GLU A CA  1 
ATOM   2233  C C   . GLU A 1 280 ? 13.622  22.958  32.132  1.00 67.24  ? 280 GLU A C   1 
ATOM   2234  O O   . GLU A 1 280 ? 14.065  22.387  33.128  1.00 83.15  ? 280 GLU A O   1 
ATOM   2235  C CB  . GLU A 1 280 ? 11.532  24.531  32.328  1.00 76.63  ? 280 GLU A CB  1 
ATOM   2236  C CG  . GLU A 1 280 ? 11.117  25.955  32.691  1.00 78.81  ? 280 GLU A CG  1 
ATOM   2237  C CD  . GLU A 1 280 ? 9.613   26.105  32.825  1.00 81.68  ? 280 GLU A CD  1 
ATOM   2238  O OE1 . GLU A 1 280 ? 9.200   27.127  33.406  1.00 88.37  ? 280 GLU A OE1 1 
ATOM   2239  O OE2 . GLU A 1 280 ? 8.862   25.213  32.366  1.00 78.38  ? 280 GLU A OE2 1 
ATOM   2240  N N   . VAL A 1 281 ? 13.654  22.414  30.909  1.00 54.68  ? 281 VAL A N   1 
ATOM   2241  C CA  . VAL A 1 281 ? 14.281  21.119  30.686  1.00 52.58  ? 281 VAL A CA  1 
ATOM   2242  C C   . VAL A 1 281 ? 15.781  21.213  30.975  1.00 62.20  ? 281 VAL A C   1 
ATOM   2243  O O   . VAL A 1 281 ? 16.357  20.342  31.631  1.00 60.97  ? 281 VAL A O   1 
ATOM   2244  C CB  . VAL A 1 281 ? 14.058  20.552  29.273  1.00 47.51  ? 281 VAL A CB  1 
ATOM   2245  C CG1 . VAL A 1 281 ? 14.766  19.211  29.080  1.00 46.17  ? 281 VAL A CG1 1 
ATOM   2246  C CG2 . VAL A 1 281 ? 12.579  20.416  28.964  1.00 48.19  ? 281 VAL A CG2 1 
ATOM   2247  N N   . LEU A 1 282 ? 16.433  22.266  30.476  1.00 62.96  ? 282 LEU A N   1 
ATOM   2248  C CA  . LEU A 1 282 ? 17.856  22.422  30.720  1.00 59.78  ? 282 LEU A CA  1 
ATOM   2249  C C   . LEU A 1 282 ? 18.142  22.485  32.230  1.00 57.73  ? 282 LEU A C   1 
ATOM   2250  O O   . LEU A 1 282 ? 19.035  21.778  32.696  1.00 47.71  ? 282 LEU A O   1 
ATOM   2251  C CB  . LEU A 1 282 ? 18.382  23.639  29.958  1.00 58.16  ? 282 LEU A CB  1 
ATOM   2252  C CG  . LEU A 1 282 ? 19.899  23.867  29.999  1.00 61.59  ? 282 LEU A CG  1 
ATOM   2253  C CD1 . LEU A 1 282 ? 20.759  22.676  29.531  1.00 58.64  ? 282 LEU A CD1 1 
ATOM   2254  C CD2 . LEU A 1 282 ? 20.183  25.097  29.161  1.00 63.64  ? 282 LEU A CD2 1 
ATOM   2255  N N   . ARG A 1 283 ? 17.389  23.304  32.996  1.00 59.60  ? 283 ARG A N   1 
ATOM   2256  C CA  . ARG A 1 283 ? 17.659  23.524  34.419  1.00 59.69  ? 283 ARG A CA  1 
ATOM   2257  C C   . ARG A 1 283 ? 17.597  22.217  35.210  1.00 58.39  ? 283 ARG A C   1 
ATOM   2258  O O   . ARG A 1 283 ? 18.392  22.023  36.138  1.00 49.28  ? 283 ARG A O   1 
ATOM   2259  C CB  . ARG A 1 283 ? 16.683  24.541  35.018  1.00 56.83  ? 283 ARG A CB  1 
ATOM   2260  C CG  . ARG A 1 283 ? 17.035  25.956  34.593  1.00 54.81  ? 283 ARG A CG  1 
ATOM   2261  C CD  . ARG A 1 283 ? 15.918  26.894  34.984  1.00 59.81  ? 283 ARG A CD  1 
ATOM   2262  N NE  . ARG A 1 283 ? 16.112  28.271  34.512  1.00 64.23  ? 283 ARG A NE  1 
ATOM   2263  C CZ  . ARG A 1 283 ? 17.056  29.118  34.942  1.00 72.99  ? 283 ARG A CZ  1 
ATOM   2264  N NH1 . ARG A 1 283 ? 18.019  28.705  35.756  1.00 73.56  ? 283 ARG A NH1 1 
ATOM   2265  N NH2 . ARG A 1 283 ? 17.051  30.384  34.543  1.00 75.51  ? 283 ARG A NH2 1 
ATOM   2266  N N   . TRP A 1 284 ? 16.627  21.380  34.796  1.00 64.63  ? 284 TRP A N   1 
ATOM   2267  C CA  . TRP A 1 284 ? 16.304  20.053  35.315  1.00 73.23  ? 284 TRP A CA  1 
ATOM   2268  C C   . TRP A 1 284 ? 17.436  19.046  35.020  1.00 78.55  ? 284 TRP A C   1 
ATOM   2269  O O   . TRP A 1 284 ? 17.808  18.247  35.892  1.00 72.15  ? 284 TRP A O   1 
ATOM   2270  C CB  . TRP A 1 284 ? 14.928  19.614  34.739  1.00 65.08  ? 284 TRP A CB  1 
ATOM   2271  C CG  . TRP A 1 284 ? 14.374  18.300  35.246  1.00 63.15  ? 284 TRP A CG  1 
ATOM   2272  C CD1 . TRP A 1 284 ? 13.677  18.111  36.408  1.00 61.80  ? 284 TRP A CD1 1 
ATOM   2273  C CD2 . TRP A 1 284 ? 14.486  16.988  34.625  1.00 62.77  ? 284 TRP A CD2 1 
ATOM   2274  N NE1 . TRP A 1 284 ? 13.385  16.782  36.576  1.00 60.87  ? 284 TRP A NE1 1 
ATOM   2275  C CE2 . TRP A 1 284 ? 13.857  16.069  35.498  1.00 64.50  ? 284 TRP A CE2 1 
ATOM   2276  C CE3 . TRP A 1 284 ? 15.055  16.494  33.434  1.00 61.53  ? 284 TRP A CE3 1 
ATOM   2277  C CZ2 . TRP A 1 284 ? 13.787  14.704  35.206  1.00 65.71  ? 284 TRP A CZ2 1 
ATOM   2278  C CZ3 . TRP A 1 284 ? 14.974  15.148  33.135  1.00 56.17  ? 284 TRP A CZ3 1 
ATOM   2279  C CH2 . TRP A 1 284 ? 14.358  14.265  34.023  1.00 66.29  ? 284 TRP A CH2 1 
ATOM   2280  N N   . ILE A 1 285 ? 17.987  19.076  33.793  1.00 75.45  ? 285 ILE A N   1 
ATOM   2281  C CA  . ILE A 1 285 ? 19.073  18.185  33.393  1.00 70.40  ? 285 ILE A CA  1 
ATOM   2282  C C   . ILE A 1 285 ? 20.364  18.581  34.117  1.00 63.90  ? 285 ILE A C   1 
ATOM   2283  O O   . ILE A 1 285 ? 21.233  17.740  34.328  1.00 60.03  ? 285 ILE A O   1 
ATOM   2284  C CB  . ILE A 1 285 ? 19.276  18.183  31.861  1.00 67.08  ? 285 ILE A CB  1 
ATOM   2285  C CG1 . ILE A 1 285 ? 18.064  17.597  31.099  1.00 70.64  ? 285 ILE A CG1 1 
ATOM   2286  C CG2 . ILE A 1 285 ? 20.582  17.483  31.476  1.00 63.36  ? 285 ILE A CG2 1 
ATOM   2287  C CD1 . ILE A 1 285 ? 18.029  16.080  30.993  1.00 71.58  ? 285 ILE A CD1 1 
ATOM   2288  N N   . GLN A 1 286 ? 20.507  19.861  34.473  1.00 66.29  ? 286 GLN A N   1 
ATOM   2289  C CA  . GLN A 1 286 ? 21.706  20.332  35.160  1.00 73.07  ? 286 GLN A CA  1 
ATOM   2290  C C   . GLN A 1 286 ? 21.601  20.049  36.664  1.00 70.00  ? 286 GLN A C   1 
ATOM   2291  O O   . GLN A 1 286 ? 22.618  19.873  37.330  1.00 67.00  ? 286 GLN A O   1 
ATOM   2292  C CB  . GLN A 1 286 ? 21.957  21.820  34.896  1.00 66.07  ? 286 GLN A CB  1 
ATOM   2293  C CG  . GLN A 1 286 ? 22.322  22.158  33.455  1.00 62.05  ? 286 GLN A CG  1 
ATOM   2294  C CD  . GLN A 1 286 ? 22.505  23.643  33.227  1.00 59.06  ? 286 GLN A CD  1 
ATOM   2295  O OE1 . GLN A 1 286 ? 23.618  24.124  32.990  1.00 61.17  ? 286 GLN A OE1 1 
ATOM   2296  N NE2 . GLN A 1 286 ? 21.422  24.395  33.345  1.00 52.67  ? 286 GLN A NE2 1 
ATOM   2297  N N   . MET A 1 287 ? 20.368  20.028  37.190  1.00 67.35  ? 287 MET A N   1 
ATOM   2298  C CA  . MET A 1 287 ? 20.104  19.732  38.589  1.00 63.55  ? 287 MET A CA  1 
ATOM   2299  C C   . MET A 1 287 ? 20.374  18.243  38.847  1.00 67.16  ? 287 MET A C   1 
ATOM   2300  O O   . MET A 1 287 ? 20.783  17.906  39.955  1.00 72.56  ? 287 MET A O   1 
ATOM   2301  C CB  . MET A 1 287 ? 18.695  20.240  38.958  1.00 60.91  ? 287 MET A CB  1 
ATOM   2302  C CG  . MET A 1 287 ? 17.986  19.542  40.105  1.00 57.45  ? 287 MET A CG  1 
ATOM   2303  S SD  . MET A 1 287 ? 17.015  18.117  39.562  1.00 62.39  ? 287 MET A SD  1 
ATOM   2304  C CE  . MET A 1 287 ? 17.754  16.552  40.032  1.00 58.65  ? 287 MET A CE  1 
ATOM   2305  N N   . LEU A 1 288 ? 20.219  17.385  37.815  1.00 72.16  ? 288 LEU A N   1 
ATOM   2306  C CA  . LEU A 1 288 ? 20.501  15.945  37.862  1.00 79.28  ? 288 LEU A CA  1 
ATOM   2307  C C   . LEU A 1 288 ? 21.998  15.610  37.776  1.00 76.82  ? 288 LEU A C   1 
ATOM   2308  O O   . LEU A 1 288 ? 22.427  14.545  38.218  1.00 79.42  ? 288 LEU A O   1 
ATOM   2309  C CB  . LEU A 1 288 ? 19.776  15.248  36.706  1.00 86.80  ? 288 LEU A CB  1 
ATOM   2310  C CG  . LEU A 1 288 ? 18.288  14.928  36.882  1.00 100.55 ? 288 LEU A CG  1 
ATOM   2311  C CD1 . LEU A 1 288 ? 17.655  14.596  35.543  1.00 107.87 ? 288 LEU A CD1 1 
ATOM   2312  C CD2 . LEU A 1 288 ? 18.072  13.766  37.827  1.00 103.31 ? 288 LEU A CD2 1 
ATOM   2313  N N   . TYR A 1 289 ? 22.771  16.464  37.097  1.00 72.24  ? 289 TYR A N   1 
ATOM   2314  C CA  . TYR A 1 289 ? 24.200  16.278  36.909  1.00 69.42  ? 289 TYR A CA  1 
ATOM   2315  C C   . TYR A 1 289 ? 24.918  16.653  38.196  1.00 60.12  ? 289 TYR A C   1 
ATOM   2316  O O   . TYR A 1 289 ? 25.893  16.017  38.545  1.00 53.57  ? 289 TYR A O   1 
ATOM   2317  C CB  . TYR A 1 289 ? 24.654  17.162  35.741  1.00 80.71  ? 289 TYR A CB  1 
ATOM   2318  C CG  . TYR A 1 289 ? 26.136  17.128  35.393  1.00 89.76  ? 289 TYR A CG  1 
ATOM   2319  C CD1 . TYR A 1 289 ? 26.723  15.956  34.929  1.00 95.50  ? 289 TYR A CD1 1 
ATOM   2320  C CD2 . TYR A 1 289 ? 26.931  18.275  35.456  1.00 94.12  ? 289 TYR A CD2 1 
ATOM   2321  C CE1 . TYR A 1 289 ? 28.066  15.905  34.591  1.00 93.89  ? 289 TYR A CE1 1 
ATOM   2322  C CE2 . TYR A 1 289 ? 28.275  18.239  35.110  1.00 92.78  ? 289 TYR A CE2 1 
ATOM   2323  C CZ  . TYR A 1 289 ? 28.841  17.047  34.681  1.00 91.65  ? 289 TYR A CZ  1 
ATOM   2324  O OH  . TYR A 1 289 ? 30.155  16.945  34.341  1.00 80.26  ? 289 TYR A OH  1 
ATOM   2325  N N   . LYS A 1 290 ? 24.412  17.688  38.875  1.00 59.70  ? 290 LYS A N   1 
ATOM   2326  C CA  . LYS A 1 290 ? 24.965  18.210  40.118  1.00 71.05  ? 290 LYS A CA  1 
ATOM   2327  C C   . LYS A 1 290 ? 24.679  17.271  41.287  1.00 80.14  ? 290 LYS A C   1 
ATOM   2328  O O   . LYS A 1 290 ? 25.420  17.246  42.271  1.00 75.05  ? 290 LYS A O   1 
ATOM   2329  C CB  . LYS A 1 290 ? 24.294  19.556  40.424  1.00 73.53  ? 290 LYS A CB  1 
ATOM   2330  C CG  . LYS A 1 290 ? 24.650  20.229  41.742  1.00 75.71  ? 290 LYS A CG  1 
ATOM   2331  C CD  . LYS A 1 290 ? 23.547  21.171  42.211  1.00 82.36  ? 290 LYS A CD  1 
ATOM   2332  C CE  . LYS A 1 290 ? 23.551  21.338  43.698  1.00 83.88  ? 290 LYS A CE  1 
ATOM   2333  N NZ  . LYS A 1 290 ? 22.195  21.494  44.228  1.00 82.40  ? 290 LYS A NZ  1 
ATOM   2334  N N   . LYS A 1 291 ? 23.555  16.556  41.187  1.00 85.64  ? 291 LYS A N   1 
ATOM   2335  C CA  . LYS A 1 291 ? 23.056  15.718  42.262  1.00 86.01  ? 291 LYS A CA  1 
ATOM   2336  C C   . LYS A 1 291 ? 23.801  14.387  42.241  1.00 84.14  ? 291 LYS A C   1 
ATOM   2337  O O   . LYS A 1 291 ? 24.049  13.815  43.299  1.00 82.32  ? 291 LYS A O   1 
ATOM   2338  C CB  . LYS A 1 291 ? 21.534  15.592  42.095  1.00 89.78  ? 291 LYS A CB  1 
ATOM   2339  C CG  . LYS A 1 291 ? 20.806  14.596  42.983  1.00 91.48  ? 291 LYS A CG  1 
ATOM   2340  C CD  . LYS A 1 291 ? 19.335  14.439  42.620  1.00 90.91  ? 291 LYS A CD  1 
ATOM   2341  C CE  . LYS A 1 291 ? 18.673  13.310  43.345  1.00 92.41  ? 291 LYS A CE  1 
ATOM   2342  N NZ  . LYS A 1 291 ? 18.544  13.589  44.778  1.00 90.35  ? 291 LYS A NZ  1 
ATOM   2343  N N   . PHE A 1 292 ? 24.172  13.918  41.040  1.00 83.34  ? 292 PHE A N   1 
ATOM   2344  C CA  . PHE A 1 292 ? 24.685  12.567  40.850  1.00 85.91  ? 292 PHE A CA  1 
ATOM   2345  C C   . PHE A 1 292 ? 26.188  12.567  40.549  1.00 86.34  ? 292 PHE A C   1 
ATOM   2346  O O   . PHE A 1 292 ? 26.741  11.518  40.219  1.00 83.54  ? 292 PHE A O   1 
ATOM   2347  C CB  . PHE A 1 292 ? 23.896  11.885  39.724  1.00 89.11  ? 292 PHE A CB  1 
ATOM   2348  C CG  . PHE A 1 292 ? 22.460  11.498  40.060  1.00 89.56  ? 292 PHE A CG  1 
ATOM   2349  C CD1 . PHE A 1 292 ? 22.157  10.828  41.240  1.00 92.67  ? 292 PHE A CD1 1 
ATOM   2350  C CD2 . PHE A 1 292 ? 21.416  11.811  39.198  1.00 91.12  ? 292 PHE A CD2 1 
ATOM   2351  C CE1 . PHE A 1 292 ? 20.852  10.474  41.545  1.00 100.66 ? 292 PHE A CE1 1 
ATOM   2352  C CE2 . PHE A 1 292 ? 20.116  11.454  39.507  1.00 101.08 ? 292 PHE A CE2 1 
ATOM   2353  C CZ  . PHE A 1 292 ? 19.835  10.788  40.679  1.00 106.47 ? 292 PHE A CZ  1 
ATOM   2354  N N   . GLY A 1 293 ? 26.845  13.735  40.662  1.00 85.64  ? 293 GLY A N   1 
ATOM   2355  C CA  . GLY A 1 293 ? 28.287  13.859  40.474  1.00 76.16  ? 293 GLY A CA  1 
ATOM   2356  C C   . GLY A 1 293 ? 28.751  13.391  39.092  1.00 72.85  ? 293 GLY A C   1 
ATOM   2357  O O   . GLY A 1 293 ? 29.876  12.931  38.940  1.00 71.00  ? 293 GLY A O   1 
ATOM   2358  N N   . GLY A 1 294 ? 27.889  13.522  38.077  1.00 74.13  ? 294 GLY A N   1 
ATOM   2359  C CA  . GLY A 1 294 ? 28.192  13.047  36.737  1.00 77.24  ? 294 GLY A CA  1 
ATOM   2360  C C   . GLY A 1 294 ? 26.914  12.614  36.024  1.00 84.01  ? 294 GLY A C   1 
ATOM   2361  O O   . GLY A 1 294 ? 25.829  13.105  36.347  1.00 87.01  ? 294 GLY A O   1 
ATOM   2362  N N   . VAL A 1 295 ? 27.075  11.702  35.053  1.00 88.81  ? 295 VAL A N   1 
ATOM   2363  C CA  . VAL A 1 295 ? 25.970  11.100  34.317  1.00 88.10  ? 295 VAL A CA  1 
ATOM   2364  C C   . VAL A 1 295 ? 25.362  9.980   35.164  1.00 92.36  ? 295 VAL A C   1 
ATOM   2365  O O   . VAL A 1 295 ? 26.049  9.005   35.468  1.00 87.27  ? 295 VAL A O   1 
ATOM   2366  C CB  . VAL A 1 295 ? 26.462  10.558  32.960  1.00 79.14  ? 295 VAL A CB  1 
ATOM   2367  C CG1 . VAL A 1 295 ? 25.353  9.835   32.200  1.00 72.59  ? 295 VAL A CG1 1 
ATOM   2368  C CG2 . VAL A 1 295 ? 27.095  11.654  32.106  1.00 77.69  ? 295 VAL A CG2 1 
ATOM   2369  N N   . PRO A 1 296 ? 24.071  10.060  35.571  1.00 94.38  ? 296 PRO A N   1 
ATOM   2370  C CA  . PRO A 1 296 ? 23.471  8.998   36.376  1.00 93.97  ? 296 PRO A CA  1 
ATOM   2371  C C   . PRO A 1 296 ? 23.405  7.694   35.581  1.00 94.56  ? 296 PRO A C   1 
ATOM   2372  O O   . PRO A 1 296 ? 23.604  7.685   34.364  1.00 82.99  ? 296 PRO A O   1 
ATOM   2373  C CB  . PRO A 1 296 ? 22.075  9.526   36.807  1.00 96.79  ? 296 PRO A CB  1 
ATOM   2374  C CG  . PRO A 1 296 ? 21.801  10.729  35.922  1.00 96.90  ? 296 PRO A CG  1 
ATOM   2375  C CD  . PRO A 1 296 ? 23.131  11.162  35.303  1.00 101.80 ? 296 PRO A CD  1 
ATOM   2376  N N   . THR A 1 297 ? 23.153  6.594   36.304  1.00 99.52  ? 297 THR A N   1 
ATOM   2377  C CA  . THR A 1 297 ? 23.047  5.269   35.714  1.00 98.08  ? 297 THR A CA  1 
ATOM   2378  C C   . THR A 1 297 ? 21.566  4.935   35.544  1.00 104.10 ? 297 THR A C   1 
ATOM   2379  O O   . THR A 1 297 ? 20.723  5.503   36.242  1.00 94.28  ? 297 THR A O   1 
ATOM   2380  C CB  . THR A 1 297 ? 23.774  4.241   36.585  1.00 86.65  ? 297 THR A CB  1 
ATOM   2381  O OG1 . THR A 1 297 ? 23.081  4.236   37.833  1.00 69.98  ? 297 THR A OG1 1 
ATOM   2382  C CG2 . THR A 1 297 ? 25.259  4.547   36.734  1.00 79.97  ? 297 THR A CG2 1 
ATOM   2383  N N   . LYS A 1 298 ? 21.275  4.005   34.620  1.00 104.71 ? 298 LYS A N   1 
ATOM   2384  C CA  . LYS A 1 298 ? 19.912  3.641   34.258  1.00 110.69 ? 298 LYS A CA  1 
ATOM   2385  C C   . LYS A 1 298 ? 19.055  3.618   35.524  1.00 114.91 ? 298 LYS A C   1 
ATOM   2386  O O   . LYS A 1 298 ? 17.934  4.136   35.532  1.00 105.61 ? 298 LYS A O   1 
ATOM   2387  C CB  . LYS A 1 298 ? 19.853  2.276   33.549  1.00 118.38 ? 298 LYS A CB  1 
ATOM   2388  C CG  . LYS A 1 298 ? 18.825  2.136   32.405  1.00 119.24 ? 298 LYS A CG  1 
ATOM   2389  C CD  . LYS A 1 298 ? 18.014  0.840   32.298  1.00 114.33 ? 298 LYS A CD  1 
ATOM   2390  C CE  . LYS A 1 298 ? 18.725  -0.447  32.602  1.00 114.23 ? 298 LYS A CE  1 
ATOM   2391  N NZ  . LYS A 1 298 ? 19.954  -0.623  31.827  1.00 118.10 ? 298 LYS A NZ  1 
ATOM   2392  N N   . GLU A 1 299 ? 19.624  3.039   36.594  1.00 110.73 ? 299 GLU A N   1 
ATOM   2393  C CA  . GLU A 1 299 ? 18.891  2.741   37.811  1.00 109.15 ? 299 GLU A CA  1 
ATOM   2394  C C   . GLU A 1 299 ? 18.617  4.014   38.617  1.00 110.55 ? 299 GLU A C   1 
ATOM   2395  O O   . GLU A 1 299 ? 17.513  4.164   39.136  1.00 121.60 ? 299 GLU A O   1 
ATOM   2396  C CB  . GLU A 1 299 ? 19.672  1.693   38.605  1.00 115.83 ? 299 GLU A CB  1 
ATOM   2397  C CG  . GLU A 1 299 ? 18.827  0.968   39.650  1.00 119.67 ? 299 GLU A CG  1 
ATOM   2398  C CD  . GLU A 1 299 ? 19.644  0.294   40.740  1.00 113.68 ? 299 GLU A CD  1 
ATOM   2399  O OE1 . GLU A 1 299 ? 20.607  -0.398  40.360  1.00 107.49 ? 299 GLU A OE1 1 
ATOM   2400  O OE2 . GLU A 1 299 ? 19.334  0.444   41.944  1.00 99.41  ? 299 GLU A OE2 1 
ATOM   2401  N N   . GLN A 1 300 ? 19.609  4.915   38.725  1.00 108.93 ? 300 GLN A N   1 
ATOM   2402  C CA  . GLN A 1 300 ? 19.508  6.113   39.559  1.00 110.93 ? 300 GLN A CA  1 
ATOM   2403  C C   . GLN A 1 300 ? 18.509  7.117   38.986  1.00 108.96 ? 300 GLN A C   1 
ATOM   2404  O O   . GLN A 1 300 ? 17.794  7.799   39.732  1.00 100.31 ? 300 GLN A O   1 
ATOM   2405  C CB  . GLN A 1 300 ? 20.814  6.905   39.631  1.00 107.93 ? 300 GLN A CB  1 
ATOM   2406  C CG  . GLN A 1 300 ? 21.963  6.191   40.331  1.00 102.96 ? 300 GLN A CG  1 
ATOM   2407  C CD  . GLN A 1 300 ? 23.282  6.903   40.115  1.00 94.89  ? 300 GLN A CD  1 
ATOM   2408  O OE1 . GLN A 1 300 ? 23.491  8.024   40.587  1.00 98.05  ? 300 GLN A OE1 1 
ATOM   2409  N NE2 . GLN A 1 300 ? 24.183  6.274   39.376  1.00 86.36  ? 300 GLN A NE2 1 
ATOM   2410  N N   . LEU A 1 301 ? 18.539  7.246   37.652  1.00 101.55 ? 301 LEU A N   1 
ATOM   2411  C CA  . LEU A 1 301 ? 17.590  8.065   36.922  1.00 97.32  ? 301 LEU A CA  1 
ATOM   2412  C C   . LEU A 1 301 ? 16.196  7.525   37.218  1.00 98.23  ? 301 LEU A C   1 
ATOM   2413  O O   . LEU A 1 301 ? 15.344  8.273   37.701  1.00 90.18  ? 301 LEU A O   1 
ATOM   2414  C CB  . LEU A 1 301 ? 17.924  8.054   35.426  1.00 97.63  ? 301 LEU A CB  1 
ATOM   2415  C CG  . LEU A 1 301 ? 17.240  9.107   34.542  1.00 95.03  ? 301 LEU A CG  1 
ATOM   2416  C CD1 . LEU A 1 301 ? 17.487  10.532  35.003  1.00 98.72  ? 301 LEU A CD1 1 
ATOM   2417  C CD2 . LEU A 1 301 ? 17.684  8.982   33.095  1.00 92.07  ? 301 LEU A CD2 1 
ATOM   2418  N N   . GLU A 1 302 ? 16.027  6.207   37.000  1.00 105.40 ? 302 GLU A N   1 
ATOM   2419  C CA  . GLU A 1 302 ? 14.733  5.537   37.068  1.00 105.33 ? 302 GLU A CA  1 
ATOM   2420  C C   . GLU A 1 302 ? 14.089  5.720   38.445  1.00 114.72 ? 302 GLU A C   1 
ATOM   2421  O O   . GLU A 1 302 ? 12.889  5.995   38.531  1.00 113.09 ? 302 GLU A O   1 
ATOM   2422  C CB  . GLU A 1 302 ? 14.828  4.050   36.719  1.00 94.83  ? 302 GLU A CB  1 
ATOM   2423  C CG  . GLU A 1 302 ? 13.452  3.435   36.469  1.00 96.80  ? 302 GLU A CG  1 
ATOM   2424  C CD  . GLU A 1 302 ? 13.342  1.937   36.672  1.00 95.77  ? 302 GLU A CD  1 
ATOM   2425  O OE1 . GLU A 1 302 ? 13.890  1.204   35.828  1.00 99.91  ? 302 GLU A OE1 1 
ATOM   2426  O OE2 . GLU A 1 302 ? 12.712  1.509   37.666  1.00 83.83  ? 302 GLU A OE2 1 
ATOM   2427  N N   . ARG A 1 303 ? 14.886  5.561   39.513  1.00 121.14 ? 303 ARG A N   1 
ATOM   2428  C CA  . ARG A 1 303 ? 14.411  5.791   40.872  1.00 132.22 ? 303 ARG A CA  1 
ATOM   2429  C C   . ARG A 1 303 ? 14.062  7.269   41.050  1.00 134.70 ? 303 ARG A C   1 
ATOM   2430  O O   . ARG A 1 303 ? 13.034  7.573   41.657  1.00 133.25 ? 303 ARG A O   1 
ATOM   2431  C CB  . ARG A 1 303 ? 15.417  5.349   41.946  1.00 138.27 ? 303 ARG A CB  1 
ATOM   2432  C CG  . ARG A 1 303 ? 14.799  5.025   43.304  1.00 134.94 ? 303 ARG A CG  1 
ATOM   2433  C CD  . ARG A 1 303 ? 15.827  4.705   44.396  1.00 127.99 ? 303 ARG A CD  1 
ATOM   2434  N NE  . ARG A 1 303 ? 16.987  3.939   43.913  1.00 122.95 ? 303 ARG A NE  1 
ATOM   2435  C CZ  . ARG A 1 303 ? 17.025  2.664   43.520  1.00 105.84 ? 303 ARG A CZ  1 
ATOM   2436  N NH1 . ARG A 1 303 ? 18.108  2.193   42.930  1.00 101.51 ? 303 ARG A NH1 1 
ATOM   2437  N NH2 . ARG A 1 303 ? 15.986  1.866   43.669  1.00 100.59 ? 303 ARG A NH2 1 
ATOM   2438  N N   . PHE A 1 304 ? 14.910  8.169   40.513  1.00 120.19 ? 304 PHE A N   1 
ATOM   2439  C CA  . PHE A 1 304 ? 14.669  9.602   40.600  1.00 111.14 ? 304 PHE A CA  1 
ATOM   2440  C C   . PHE A 1 304 ? 13.394  9.979   39.834  1.00 109.41 ? 304 PHE A C   1 
ATOM   2441  O O   . PHE A 1 304 ? 12.686  10.909  40.224  1.00 96.84  ? 304 PHE A O   1 
ATOM   2442  C CB  . PHE A 1 304 ? 15.833  10.464  40.096  1.00 102.24 ? 304 PHE A CB  1 
ATOM   2443  C CG  . PHE A 1 304 ? 15.478  11.938  40.229  1.00 91.08  ? 304 PHE A CG  1 
ATOM   2444  C CD1 . PHE A 1 304 ? 15.678  12.602  41.433  1.00 88.12  ? 304 PHE A CD1 1 
ATOM   2445  C CD2 . PHE A 1 304 ? 14.850  12.624  39.191  1.00 85.90  ? 304 PHE A CD2 1 
ATOM   2446  C CE1 . PHE A 1 304 ? 15.302  13.932  41.582  1.00 95.55  ? 304 PHE A CE1 1 
ATOM   2447  C CE2 . PHE A 1 304 ? 14.468  13.951  39.345  1.00 92.51  ? 304 PHE A CE2 1 
ATOM   2448  C CZ  . PHE A 1 304 ? 14.702  14.607  40.537  1.00 96.98  ? 304 PHE A CZ  1 
ATOM   2449  N N   . ALA A 1 305 ? 13.103  9.257   38.744  1.00 108.49 ? 305 ALA A N   1 
ATOM   2450  C CA  . ALA A 1 305 ? 11.936  9.524   37.915  1.00 114.11 ? 305 ALA A CA  1 
ATOM   2451  C C   . ALA A 1 305 ? 10.640  9.112   38.618  1.00 120.52 ? 305 ALA A C   1 
ATOM   2452  O O   . ALA A 1 305 ? 9.639   9.825   38.514  1.00 101.95 ? 305 ALA A O   1 
ATOM   2453  C CB  . ALA A 1 305 ? 12.086  8.820   36.581  1.00 117.14 ? 305 ALA A CB  1 
ATOM   2454  N N   . TRP A 1 306 ? 10.666  7.955   39.306  1.00 130.23 ? 306 TRP A N   1 
ATOM   2455  C CA  . TRP A 1 306 ? 9.522   7.455   40.060  1.00 120.54 ? 306 TRP A CA  1 
ATOM   2456  C C   . TRP A 1 306 ? 9.174   8.382   41.222  1.00 121.62 ? 306 TRP A C   1 
ATOM   2457  O O   . TRP A 1 306 ? 7.996   8.553   41.524  1.00 124.47 ? 306 TRP A O   1 
ATOM   2458  C CB  . TRP A 1 306 ? 9.778   6.032   40.574  1.00 118.89 ? 306 TRP A CB  1 
ATOM   2459  C CG  . TRP A 1 306 ? 9.390   4.962   39.592  1.00 127.83 ? 306 TRP A CG  1 
ATOM   2460  C CD1 . TRP A 1 306 ? 10.219  4.127   38.903  1.00 123.82 ? 306 TRP A CD1 1 
ATOM   2461  C CD2 . TRP A 1 306 ? 8.048   4.635   39.172  1.00 144.28 ? 306 TRP A CD2 1 
ATOM   2462  N NE1 . TRP A 1 306 ? 9.490   3.292   38.099  1.00 126.86 ? 306 TRP A NE1 1 
ATOM   2463  C CE2 . TRP A 1 306 ? 8.157   3.582   38.236  1.00 139.60 ? 306 TRP A CE2 1 
ATOM   2464  C CE3 . TRP A 1 306 ? 6.775   5.123   39.493  1.00 150.91 ? 306 TRP A CE3 1 
ATOM   2465  C CZ2 . TRP A 1 306 ? 7.039   3.014   37.625  1.00 143.88 ? 306 TRP A CZ2 1 
ATOM   2466  C CZ3 . TRP A 1 306 ? 5.673   4.564   38.882  1.00 151.01 ? 306 TRP A CZ3 1 
ATOM   2467  C CH2 . TRP A 1 306 ? 5.805   3.524   37.961  1.00 147.71 ? 306 TRP A CH2 1 
ATOM   2468  N N   . ASP A 1 307 ? 10.202  8.961   41.862  1.00 126.14 ? 307 ASP A N   1 
ATOM   2469  C CA  . ASP A 1 307 ? 10.035  9.829   43.021  1.00 127.46 ? 307 ASP A CA  1 
ATOM   2470  C C   . ASP A 1 307 ? 9.400   11.168  42.633  1.00 140.76 ? 307 ASP A C   1 
ATOM   2471  O O   . ASP A 1 307 ? 8.519   11.651  43.346  1.00 145.63 ? 307 ASP A O   1 
ATOM   2472  C CB  . ASP A 1 307 ? 11.349  10.041  43.761  1.00 114.48 ? 307 ASP A CB  1 
ATOM   2473  C CG  . ASP A 1 307 ? 11.820  8.876   44.621  1.00 107.16 ? 307 ASP A CG  1 
ATOM   2474  O OD1 . ASP A 1 307 ? 12.038  7.770   44.062  1.00 96.46  ? 307 ASP A OD1 1 
ATOM   2475  O OD2 . ASP A 1 307 ? 11.968  9.091   45.845  1.00 101.12 ? 307 ASP A OD2 1 
ATOM   2476  N N   . THR A 1 308 ? 9.862   11.775  41.526  1.00 139.85 ? 308 THR A N   1 
ATOM   2477  C CA  . THR A 1 308 ? 9.328   13.055  41.072  1.00 131.69 ? 308 THR A CA  1 
ATOM   2478  C C   . THR A 1 308 ? 7.850   12.873  40.712  1.00 133.24 ? 308 THR A C   1 
ATOM   2479  O O   . THR A 1 308 ? 7.041   13.736  41.047  1.00 129.36 ? 308 THR A O   1 
ATOM   2480  C CB  . THR A 1 308 ? 10.180  13.641  39.935  1.00 114.37 ? 308 THR A CB  1 
ATOM   2481  O OG1 . THR A 1 308 ? 11.272  14.335  40.533  1.00 99.72  ? 308 THR A OG1 1 
ATOM   2482  C CG2 . THR A 1 308 ? 9.488   14.715  39.117  1.00 104.47 ? 308 THR A CG2 1 
ATOM   2483  N N   . LEU A 1 309 ? 7.502   11.733  40.084  1.00 127.49 ? 309 LEU A N   1 
ATOM   2484  C CA  . LEU A 1 309 ? 6.124   11.420  39.716  1.00 122.44 ? 309 LEU A CA  1 
ATOM   2485  C C   . LEU A 1 309 ? 5.293   11.159  40.981  1.00 111.17 ? 309 LEU A C   1 
ATOM   2486  O O   . LEU A 1 309 ? 4.225   11.747  41.161  1.00 92.70  ? 309 LEU A O   1 
ATOM   2487  C CB  . LEU A 1 309 ? 6.040   10.250  38.721  1.00 121.85 ? 309 LEU A CB  1 
ATOM   2488  C CG  . LEU A 1 309 ? 6.328   10.544  37.236  1.00 114.90 ? 309 LEU A CG  1 
ATOM   2489  C CD1 . LEU A 1 309 ? 6.430   9.256   36.421  1.00 104.39 ? 309 LEU A CD1 1 
ATOM   2490  C CD2 . LEU A 1 309 ? 5.296   11.454  36.573  1.00 113.09 ? 309 LEU A CD2 1 
ATOM   2491  N N   . ASN A 1 310 ? 5.794   10.305  41.883  1.00 108.46 ? 310 ASN A N   1 
ATOM   2492  C CA  . ASN A 1 310 ? 5.038   9.903   43.064  1.00 107.88 ? 310 ASN A CA  1 
ATOM   2493  C C   . ASN A 1 310 ? 4.731   11.094  43.974  1.00 109.13 ? 310 ASN A C   1 
ATOM   2494  O O   . ASN A 1 310 ? 3.895   10.961  44.860  1.00 105.56 ? 310 ASN A O   1 
ATOM   2495  C CB  . ASN A 1 310 ? 5.748   8.816   43.871  1.00 106.55 ? 310 ASN A CB  1 
ATOM   2496  C CG  . ASN A 1 310 ? 5.540   7.422   43.320  1.00 108.40 ? 310 ASN A CG  1 
ATOM   2497  O OD1 . ASN A 1 310 ? 4.760   7.226   42.383  1.00 106.44 ? 310 ASN A OD1 1 
ATOM   2498  N ND2 . ASN A 1 310 ? 6.214   6.435   43.896  1.00 103.70 ? 310 ASN A ND2 1 
ATOM   2499  N N   . SER A 1 311 ? 5.401   12.240  43.773  1.00 116.41 ? 311 SER A N   1 
ATOM   2500  C CA  . SER A 1 311 ? 5.200   13.414  44.615  1.00 117.05 ? 311 SER A CA  1 
ATOM   2501  C C   . SER A 1 311 ? 4.253   14.433  43.969  1.00 118.57 ? 311 SER A C   1 
ATOM   2502  O O   . SER A 1 311 ? 3.936   15.448  44.590  1.00 99.07  ? 311 SER A O   1 
ATOM   2503  C CB  . SER A 1 311 ? 6.529   14.048  44.974  1.00 118.87 ? 311 SER A CB  1 
ATOM   2504  O OG  . SER A 1 311 ? 7.218   14.510  43.818  1.00 130.17 ? 311 SER A OG  1 
ATOM   2505  N N   . GLY A 1 312 ? 3.804   14.171  42.730  1.00 133.19 ? 312 GLY A N   1 
ATOM   2506  C CA  . GLY A 1 312 ? 2.878   15.052  42.023  1.00 140.62 ? 312 GLY A CA  1 
ATOM   2507  C C   . GLY A 1 312 ? 3.597   16.147  41.226  1.00 142.71 ? 312 GLY A C   1 
ATOM   2508  O O   . GLY A 1 312 ? 3.246   17.325  41.320  1.00 132.50 ? 312 GLY A O   1 
ATOM   2509  N N   . GLN A 1 313 ? 4.603   15.738  40.440  1.00 136.33 ? 313 GLN A N   1 
ATOM   2510  C CA  . GLN A 1 313 ? 5.378   16.629  39.590  1.00 119.72 ? 313 GLN A CA  1 
ATOM   2511  C C   . GLN A 1 313 ? 5.362   16.078  38.162  1.00 121.80 ? 313 GLN A C   1 
ATOM   2512  O O   . GLN A 1 313 ? 4.975   14.927  37.954  1.00 99.34  ? 313 GLN A O   1 
ATOM   2513  C CB  . GLN A 1 313 ? 6.829   16.712  40.073  1.00 117.70 ? 313 GLN A CB  1 
ATOM   2514  C CG  . GLN A 1 313 ? 7.020   17.088  41.540  1.00 111.30 ? 313 GLN A CG  1 
ATOM   2515  C CD  . GLN A 1 313 ? 6.917   18.574  41.785  1.00 104.50 ? 313 GLN A CD  1 
ATOM   2516  O OE1 . GLN A 1 313 ? 7.891   19.224  42.182  1.00 89.77  ? 313 GLN A OE1 1 
ATOM   2517  N NE2 . GLN A 1 313 ? 5.737   19.124  41.533  1.00 98.63  ? 313 GLN A NE2 1 
ATOM   2518  N N   . VAL A 1 314 ? 5.827   16.903  37.204  1.00 138.19 ? 314 VAL A N   1 
ATOM   2519  C CA  . VAL A 1 314 ? 5.892   16.574  35.779  1.00 136.29 ? 314 VAL A CA  1 
ATOM   2520  C C   . VAL A 1 314 ? 7.355   16.333  35.376  1.00 121.71 ? 314 VAL A C   1 
ATOM   2521  O O   . VAL A 1 314 ? 8.233   17.038  35.865  1.00 121.40 ? 314 VAL A O   1 
ATOM   2522  C CB  . VAL A 1 314 ? 5.257   17.686  34.902  1.00 138.82 ? 314 VAL A CB  1 
ATOM   2523  C CG1 . VAL A 1 314 ? 3.733   17.587  34.842  1.00 135.83 ? 314 VAL A CG1 1 
ATOM   2524  C CG2 . VAL A 1 314 ? 5.692   19.102  35.295  1.00 127.43 ? 314 VAL A CG2 1 
ATOM   2525  N N   . ILE A 1 315 ? 7.613   15.355  34.480  1.00 114.79 ? 315 ILE A N   1 
ATOM   2526  C CA  . ILE A 1 315 ? 8.927   15.153  33.859  1.00 113.35 ? 315 ILE A CA  1 
ATOM   2527  C C   . ILE A 1 315 ? 9.096   16.111  32.674  1.00 119.95 ? 315 ILE A C   1 
ATOM   2528  O O   . ILE A 1 315 ? 8.590   15.815  31.591  1.00 126.19 ? 315 ILE A O   1 
ATOM   2529  C CB  . ILE A 1 315 ? 9.136   13.696  33.381  1.00 96.88  ? 315 ILE A CB  1 
ATOM   2530  C CG1 . ILE A 1 315 ? 9.167   12.701  34.540  1.00 94.82  ? 315 ILE A CG1 1 
ATOM   2531  C CG2 . ILE A 1 315 ? 10.405  13.584  32.529  1.00 89.47  ? 315 ILE A CG2 1 
ATOM   2532  C CD1 . ILE A 1 315 ? 9.270   11.248  34.111  1.00 92.05  ? 315 ILE A CD1 1 
ATOM   2533  N N   . PRO A 1 316 ? 9.862   17.231  32.784  1.00 115.69 ? 316 PRO A N   1 
ATOM   2534  C CA  . PRO A 1 316 ? 9.857   18.268  31.744  1.00 112.12 ? 316 PRO A CA  1 
ATOM   2535  C C   . PRO A 1 316 ? 10.188  17.762  30.335  1.00 101.44 ? 316 PRO A C   1 
ATOM   2536  O O   . PRO A 1 316 ? 11.001  16.847  30.160  1.00 86.76  ? 316 PRO A O   1 
ATOM   2537  C CB  . PRO A 1 316 ? 10.884  19.311  32.242  1.00 111.82 ? 316 PRO A CB  1 
ATOM   2538  C CG  . PRO A 1 316 ? 11.003  19.054  33.730  1.00 114.68 ? 316 PRO A CG  1 
ATOM   2539  C CD  . PRO A 1 316 ? 10.795  17.554  33.879  1.00 113.78 ? 316 PRO A CD  1 
ATOM   2540  N N   . GLY A 1 317 ? 9.511   18.366  29.344  1.00 94.56  ? 317 GLY A N   1 
ATOM   2541  C CA  . GLY A 1 317 ? 9.776   18.121  27.935  1.00 87.71  ? 317 GLY A CA  1 
ATOM   2542  C C   . GLY A 1 317 ? 9.169   16.814  27.430  1.00 84.53  ? 317 GLY A C   1 
ATOM   2543  O O   . GLY A 1 317 ? 9.543   16.333  26.364  1.00 77.36  ? 317 GLY A O   1 
ATOM   2544  N N   . TYR A 1 318 ? 8.233   16.239  28.193  1.00 89.66  ? 318 TYR A N   1 
ATOM   2545  C CA  . TYR A 1 318 ? 7.560   15.011  27.795  1.00 87.95  ? 318 TYR A CA  1 
ATOM   2546  C C   . TYR A 1 318 ? 6.049   15.267  27.820  1.00 93.44  ? 318 TYR A C   1 
ATOM   2547  O O   . TYR A 1 318 ? 5.551   15.833  28.788  1.00 97.72  ? 318 TYR A O   1 
ATOM   2548  C CB  . TYR A 1 318 ? 8.162   13.963  28.743  1.00 81.64  ? 318 TYR A CB  1 
ATOM   2549  C CG  . TYR A 1 318 ? 9.552   13.456  28.363  1.00 73.89  ? 318 TYR A CG  1 
ATOM   2550  C CD1 . TYR A 1 318 ? 10.723  14.153  28.678  1.00 68.59  ? 318 TYR A CD1 1 
ATOM   2551  C CD2 . TYR A 1 318 ? 9.694   12.243  27.698  1.00 74.06  ? 318 TYR A CD2 1 
ATOM   2552  C CE1 . TYR A 1 318 ? 11.976  13.669  28.309  1.00 66.95  ? 318 TYR A CE1 1 
ATOM   2553  C CE2 . TYR A 1 318 ? 10.936  11.747  27.329  1.00 73.00  ? 318 TYR A CE2 1 
ATOM   2554  C CZ  . TYR A 1 318 ? 12.085  12.457  27.631  1.00 68.02  ? 318 TYR A CZ  1 
ATOM   2555  O OH  . TYR A 1 318 ? 13.262  11.880  27.214  1.00 65.96  ? 318 TYR A OH  1 
ATOM   2556  N N   . GLY A 1 319 ? 5.327   14.918  26.738  1.00 94.31  ? 319 GLY A N   1 
ATOM   2557  C CA  . GLY A 1 319 ? 3.874   15.079  26.681  1.00 92.39  ? 319 GLY A CA  1 
ATOM   2558  C C   . GLY A 1 319 ? 3.437   16.459  26.169  1.00 88.19  ? 319 GLY A C   1 
ATOM   2559  O O   . GLY A 1 319 ? 4.126   17.454  26.378  1.00 80.07  ? 319 GLY A O   1 
ATOM   2560  N N   . HIS A 1 320 ? 2.257   16.531  25.534  1.00 87.16  ? 320 HIS A N   1 
ATOM   2561  C CA  . HIS A 1 320 ? 1.894   17.712  24.757  1.00 89.55  ? 320 HIS A CA  1 
ATOM   2562  C C   . HIS A 1 320 ? 0.372   17.879  24.635  1.00 82.09  ? 320 HIS A C   1 
ATOM   2563  O O   . HIS A 1 320 ? -0.390  17.049  25.124  1.00 84.79  ? 320 HIS A O   1 
ATOM   2564  C CB  . HIS A 1 320 ? 2.601   17.615  23.395  1.00 94.21  ? 320 HIS A CB  1 
ATOM   2565  C CG  . HIS A 1 320 ? 2.603   18.857  22.554  1.00 81.25  ? 320 HIS A CG  1 
ATOM   2566  N ND1 . HIS A 1 320 ? 1.970   18.916  21.331  1.00 66.64  ? 320 HIS A ND1 1 
ATOM   2567  C CD2 . HIS A 1 320 ? 3.195   20.051  22.721  1.00 79.94  ? 320 HIS A CD2 1 
ATOM   2568  C CE1 . HIS A 1 320 ? 2.144   20.122  20.807  1.00 71.66  ? 320 HIS A CE1 1 
ATOM   2569  N NE2 . HIS A 1 320 ? 2.885   20.827  21.633  1.00 74.55  ? 320 HIS A NE2 1 
ATOM   2570  N N   . ALA A 1 321 ? -0.044  18.967  23.957  1.00 75.97  ? 321 ALA A N   1 
ATOM   2571  C CA  . ALA A 1 321 ? -1.436  19.383  23.786  1.00 77.30  ? 321 ALA A CA  1 
ATOM   2572  C C   . ALA A 1 321 ? -2.146  18.712  22.606  1.00 81.63  ? 321 ALA A C   1 
ATOM   2573  O O   . ALA A 1 321 ? -3.367  18.861  22.497  1.00 74.07  ? 321 ALA A O   1 
ATOM   2574  C CB  . ALA A 1 321 ? -1.493  20.895  23.594  1.00 70.57  ? 321 ALA A CB  1 
ATOM   2575  N N   . VAL A 1 322 ? -1.365  18.102  21.685  1.00 89.83  ? 322 VAL A N   1 
ATOM   2576  C CA  . VAL A 1 322 ? -1.855  17.431  20.478  1.00 76.02  ? 322 VAL A CA  1 
ATOM   2577  C C   . VAL A 1 322 ? -0.988  16.203  20.159  1.00 68.41  ? 322 VAL A C   1 
ATOM   2578  O O   . VAL A 1 322 ? -1.513  15.228  19.643  1.00 61.94  ? 322 VAL A O   1 
ATOM   2579  C CB  . VAL A 1 322 ? -1.969  18.342  19.230  1.00 78.50  ? 322 VAL A CB  1 
ATOM   2580  C CG1 . VAL A 1 322 ? -3.110  19.350  19.316  1.00 81.39  ? 322 VAL A CG1 1 
ATOM   2581  C CG2 . VAL A 1 322 ? -0.678  19.085  18.933  1.00 85.75  ? 322 VAL A CG2 1 
ATOM   2582  N N   . LEU A 1 323 ? 0.328   16.242  20.447  1.00 78.73  ? 323 LEU A N   1 
ATOM   2583  C CA  . LEU A 1 323 ? 1.271   15.164  20.136  1.00 79.09  ? 323 LEU A CA  1 
ATOM   2584  C C   . LEU A 1 323 ? 0.958   13.912  20.955  1.00 70.70  ? 323 LEU A C   1 
ATOM   2585  O O   . LEU A 1 323 ? 0.353   14.001  22.016  1.00 72.48  ? 323 LEU A O   1 
ATOM   2586  C CB  . LEU A 1 323 ? 2.727   15.575  20.400  1.00 81.79  ? 323 LEU A CB  1 
ATOM   2587  C CG  . LEU A 1 323 ? 3.619   15.991  19.220  1.00 80.40  ? 323 LEU A CG  1 
ATOM   2588  C CD1 . LEU A 1 323 ? 3.455   15.109  17.981  1.00 79.96  ? 323 LEU A CD1 1 
ATOM   2589  C CD2 . LEU A 1 323 ? 3.440   17.458  18.873  1.00 77.38  ? 323 LEU A CD2 1 
ATOM   2590  N N   . ARG A 1 324 ? 1.436   12.760  20.469  1.00 73.41  ? 324 ARG A N   1 
ATOM   2591  C CA  . ARG A 1 324 ? 1.322   11.487  21.174  1.00 79.86  ? 324 ARG A CA  1 
ATOM   2592  C C   . ARG A 1 324 ? 2.490   10.552  20.845  1.00 86.51  ? 324 ARG A C   1 
ATOM   2593  O O   . ARG A 1 324 ? 2.655   9.538   21.524  1.00 96.98  ? 324 ARG A O   1 
ATOM   2594  C CB  . ARG A 1 324 ? 0.014   10.737  20.860  1.00 83.19  ? 324 ARG A CB  1 
ATOM   2595  C CG  . ARG A 1 324 ? -1.103  10.704  21.901  1.00 79.06  ? 324 ARG A CG  1 
ATOM   2596  C CD  . ARG A 1 324 ? -2.279  11.663  21.705  1.00 69.78  ? 324 ARG A CD  1 
ATOM   2597  N NE  . ARG A 1 324 ? -2.063  13.024  22.210  1.00 67.75  ? 324 ARG A NE  1 
ATOM   2598  C CZ  . ARG A 1 324 ? -2.907  13.735  22.954  1.00 71.09  ? 324 ARG A CZ  1 
ATOM   2599  N NH1 . ARG A 1 324 ? -2.683  15.020  23.212  1.00 72.19  ? 324 ARG A NH1 1 
ATOM   2600  N NH2 . ARG A 1 324 ? -4.008  13.171  23.400  1.00 75.49  ? 324 ARG A NH2 1 
ATOM   2601  N N   . VAL A 1 325 ? 3.277   10.853  19.800  1.00 86.36  ? 325 VAL A N   1 
ATOM   2602  C CA  . VAL A 1 325 ? 4.517   10.124  19.551  1.00 98.71  ? 325 VAL A CA  1 
ATOM   2603  C C   . VAL A 1 325 ? 5.720   11.032  19.872  1.00 98.63  ? 325 VAL A C   1 
ATOM   2604  O O   . VAL A 1 325 ? 5.565   12.119  20.446  1.00 88.22  ? 325 VAL A O   1 
ATOM   2605  C CB  . VAL A 1 325 ? 4.573   9.492   18.135  1.00 95.02  ? 325 VAL A CB  1 
ATOM   2606  C CG1 . VAL A 1 325 ? 3.640   8.289   18.008  1.00 87.91  ? 325 VAL A CG1 1 
ATOM   2607  C CG2 . VAL A 1 325 ? 4.295   10.490  17.016  1.00 90.07  ? 325 VAL A CG2 1 
ATOM   2608  N N   . THR A 1 326 ? 6.935   10.527  19.590  1.00 92.01  ? 326 THR A N   1 
ATOM   2609  C CA  . THR A 1 326 ? 8.167   11.292  19.727  1.00 86.93  ? 326 THR A CA  1 
ATOM   2610  C C   . THR A 1 326 ? 8.138   12.431  18.714  1.00 74.46  ? 326 THR A C   1 
ATOM   2611  O O   . THR A 1 326 ? 8.098   12.176  17.509  1.00 61.64  ? 326 THR A O   1 
ATOM   2612  C CB  . THR A 1 326 ? 9.389   10.394  19.490  1.00 89.41  ? 326 THR A CB  1 
ATOM   2613  O OG1 . THR A 1 326 ? 9.391   9.389   20.497  1.00 100.09 ? 326 THR A OG1 1 
ATOM   2614  C CG2 . THR A 1 326 ? 10.715  11.131  19.578  1.00 86.96  ? 326 THR A CG2 1 
ATOM   2615  N N   . ASP A 1 327 ? 8.194   13.675  19.210  1.00 62.42  ? 327 ASP A N   1 
ATOM   2616  C CA  . ASP A 1 327 ? 8.291   14.840  18.340  1.00 54.04  ? 327 ASP A CA  1 
ATOM   2617  C C   . ASP A 1 327 ? 9.393   14.598  17.304  1.00 52.08  ? 327 ASP A C   1 
ATOM   2618  O O   . ASP A 1 327 ? 10.474  14.114  17.632  1.00 52.55  ? 327 ASP A O   1 
ATOM   2619  C CB  . ASP A 1 327 ? 8.420   16.113  19.162  1.00 48.27  ? 327 ASP A CB  1 
ATOM   2620  C CG  . ASP A 1 327 ? 8.249   17.399  18.371  1.00 45.43  ? 327 ASP A CG  1 
ATOM   2621  O OD1 . ASP A 1 327 ? 8.468   17.354  17.162  1.00 40.60  ? 327 ASP A OD1 1 
ATOM   2622  O OD2 . ASP A 1 327 ? 7.873   18.430  18.965  1.00 42.82  ? 327 ASP A OD2 1 
ATOM   2623  N N   . PRO A 1 328 ? 9.153   14.837  15.995  1.00 52.94  ? 328 PRO A N   1 
ATOM   2624  C CA  . PRO A 1 328 ? 10.227  14.700  15.008  1.00 56.08  ? 328 PRO A CA  1 
ATOM   2625  C C   . PRO A 1 328 ? 11.224  15.866  15.037  1.00 54.65  ? 328 PRO A C   1 
ATOM   2626  O O   . PRO A 1 328 ? 12.298  15.796  14.422  1.00 55.41  ? 328 PRO A O   1 
ATOM   2627  C CB  . PRO A 1 328 ? 9.477   14.550  13.681  1.00 53.56  ? 328 PRO A CB  1 
ATOM   2628  C CG  . PRO A 1 328 ? 8.144   15.250  13.918  1.00 54.55  ? 328 PRO A CG  1 
ATOM   2629  C CD  . PRO A 1 328 ? 7.849   15.160  15.398  1.00 53.44  ? 328 PRO A CD  1 
ATOM   2630  N N   . ARG A 1 329 ? 10.865  16.904  15.804  1.00 47.77  ? 329 ARG A N   1 
ATOM   2631  C CA  . ARG A 1 329 ? 11.752  18.013  16.122  1.00 48.02  ? 329 ARG A CA  1 
ATOM   2632  C C   . ARG A 1 329 ? 12.782  17.591  17.177  1.00 51.90  ? 329 ARG A C   1 
ATOM   2633  O O   . ARG A 1 329 ? 13.936  18.018  17.130  1.00 52.46  ? 329 ARG A O   1 
ATOM   2634  C CB  . ARG A 1 329 ? 10.898  19.217  16.537  1.00 44.18  ? 329 ARG A CB  1 
ATOM   2635  C CG  . ARG A 1 329 ? 9.891   19.619  15.462  1.00 45.09  ? 329 ARG A CG  1 
ATOM   2636  C CD  . ARG A 1 329 ? 9.023   20.809  15.855  1.00 43.60  ? 329 ARG A CD  1 
ATOM   2637  N NE  . ARG A 1 329 ? 8.156   20.571  17.011  1.00 41.51  ? 329 ARG A NE  1 
ATOM   2638  C CZ  . ARG A 1 329 ? 7.491   21.531  17.633  1.00 44.10  ? 329 ARG A CZ  1 
ATOM   2639  N NH1 . ARG A 1 329 ? 7.342   22.721  17.081  1.00 45.95  ? 329 ARG A NH1 1 
ATOM   2640  N NH2 . ARG A 1 329 ? 6.949   21.294  18.810  1.00 48.34  ? 329 ARG A NH2 1 
ATOM   2641  N N   . TYR A 1 330 ? 12.360  16.764  18.140  1.00 48.94  ? 330 TYR A N   1 
ATOM   2642  C CA  . TYR A 1 330 ? 13.268  16.155  19.093  1.00 47.43  ? 330 TYR A CA  1 
ATOM   2643  C C   . TYR A 1 330 ? 14.221  15.219  18.363  1.00 47.83  ? 330 TYR A C   1 
ATOM   2644  O O   . TYR A 1 330 ? 15.423  15.259  18.596  1.00 56.46  ? 330 TYR A O   1 
ATOM   2645  C CB  . TYR A 1 330 ? 12.474  15.395  20.158  1.00 55.01  ? 330 TYR A CB  1 
ATOM   2646  C CG  . TYR A 1 330 ? 13.329  14.697  21.208  1.00 56.83  ? 330 TYR A CG  1 
ATOM   2647  C CD1 . TYR A 1 330 ? 13.924  13.458  20.964  1.00 60.33  ? 330 TYR A CD1 1 
ATOM   2648  C CD2 . TYR A 1 330 ? 13.531  15.279  22.450  1.00 55.79  ? 330 TYR A CD2 1 
ATOM   2649  C CE1 . TYR A 1 330 ? 14.696  12.823  21.926  1.00 59.32  ? 330 TYR A CE1 1 
ATOM   2650  C CE2 . TYR A 1 330 ? 14.305  14.658  23.417  1.00 63.26  ? 330 TYR A CE2 1 
ATOM   2651  C CZ  . TYR A 1 330 ? 14.887  13.426  23.160  1.00 65.51  ? 330 TYR A CZ  1 
ATOM   2652  O OH  . TYR A 1 330 ? 15.644  12.863  24.156  1.00 73.25  ? 330 TYR A OH  1 
ATOM   2653  N N   . VAL A 1 331 ? 13.694  14.391  17.458  1.00 45.86  ? 331 VAL A N   1 
ATOM   2654  C CA  . VAL A 1 331 ? 14.531  13.430  16.755  1.00 44.93  ? 331 VAL A CA  1 
ATOM   2655  C C   . VAL A 1 331 ? 15.613  14.167  15.981  1.00 47.03  ? 331 VAL A C   1 
ATOM   2656  O O   . VAL A 1 331 ? 16.757  13.731  15.972  1.00 54.17  ? 331 VAL A O   1 
ATOM   2657  C CB  . VAL A 1 331 ? 13.745  12.510  15.801  1.00 47.41  ? 331 VAL A CB  1 
ATOM   2658  C CG1 . VAL A 1 331 ? 14.671  11.689  14.896  1.00 48.94  ? 331 VAL A CG1 1 
ATOM   2659  C CG2 . VAL A 1 331 ? 12.772  11.615  16.555  1.00 48.60  ? 331 VAL A CG2 1 
ATOM   2660  N N   . ALA A 1 332 ? 15.221  15.242  15.290  1.00 51.39  ? 332 ALA A N   1 
ATOM   2661  C CA  . ALA A 1 332 ? 16.142  16.010  14.472  1.00 50.43  ? 332 ALA A CA  1 
ATOM   2662  C C   . ALA A 1 332 ? 17.266  16.624  15.315  1.00 49.43  ? 332 ALA A C   1 
ATOM   2663  O O   . ALA A 1 332 ? 18.402  16.722  14.851  1.00 49.22  ? 332 ALA A O   1 
ATOM   2664  C CB  . ALA A 1 332 ? 15.373  17.065  13.716  1.00 48.84  ? 332 ALA A CB  1 
ATOM   2665  N N   . GLN A 1 333 ? 16.959  17.043  16.550  1.00 48.17  ? 333 GLN A N   1 
ATOM   2666  C CA  . GLN A 1 333 ? 17.955  17.664  17.418  1.00 51.18  ? 333 GLN A CA  1 
ATOM   2667  C C   . GLN A 1 333 ? 18.901  16.631  18.031  1.00 59.52  ? 333 GLN A C   1 
ATOM   2668  O O   . GLN A 1 333 ? 20.090  16.901  18.185  1.00 59.10  ? 333 GLN A O   1 
ATOM   2669  C CB  . GLN A 1 333 ? 17.275  18.454  18.530  1.00 46.36  ? 333 GLN A CB  1 
ATOM   2670  C CG  . GLN A 1 333 ? 16.649  19.746  18.033  1.00 44.72  ? 333 GLN A CG  1 
ATOM   2671  C CD  . GLN A 1 333 ? 15.921  20.489  19.126  1.00 45.97  ? 333 GLN A CD  1 
ATOM   2672  O OE1 . GLN A 1 333 ? 16.446  21.455  19.686  1.00 44.68  ? 333 GLN A OE1 1 
ATOM   2673  N NE2 . GLN A 1 333 ? 14.716  20.028  19.444  1.00 44.87  ? 333 GLN A NE2 1 
ATOM   2674  N N   . ARG A 1 334 ? 18.349  15.478  18.424  1.00 65.04  ? 334 ARG A N   1 
ATOM   2675  C CA  . ARG A 1 334 ? 19.128  14.289  18.727  1.00 62.73  ? 334 ARG A CA  1 
ATOM   2676  C C   . ARG A 1 334 ? 20.139  13.995  17.615  1.00 59.00  ? 334 ARG A C   1 
ATOM   2677  O O   . ARG A 1 334 ? 21.329  13.862  17.880  1.00 59.81  ? 334 ARG A O   1 
ATOM   2678  C CB  . ARG A 1 334 ? 18.159  13.118  18.911  1.00 72.88  ? 334 ARG A CB  1 
ATOM   2679  C CG  . ARG A 1 334 ? 18.795  11.880  19.517  1.00 84.40  ? 334 ARG A CG  1 
ATOM   2680  C CD  . ARG A 1 334 ? 17.778  10.796  19.847  1.00 95.49  ? 334 ARG A CD  1 
ATOM   2681  N NE  . ARG A 1 334 ? 18.524  9.577   20.168  1.00 102.17 ? 334 ARG A NE  1 
ATOM   2682  C CZ  . ARG A 1 334 ? 19.330  9.476   21.215  1.00 103.12 ? 334 ARG A CZ  1 
ATOM   2683  N NH1 . ARG A 1 334 ? 19.187  10.297  22.251  1.00 96.72  ? 334 ARG A NH1 1 
ATOM   2684  N NH2 . ARG A 1 334 ? 20.246  8.524   21.226  1.00 100.27 ? 334 ARG A NH2 1 
ATOM   2685  N N   . ASP A 1 335 ? 19.682  13.883  16.363  1.00 56.48  ? 335 ASP A N   1 
ATOM   2686  C CA  . ASP A 1 335 ? 20.592  13.590  15.262  1.00 55.20  ? 335 ASP A CA  1 
ATOM   2687  C C   . ASP A 1 335 ? 21.768  14.563  15.321  1.00 56.76  ? 335 ASP A C   1 
ATOM   2688  O O   . ASP A 1 335 ? 22.917  14.159  15.127  1.00 58.56  ? 335 ASP A O   1 
ATOM   2689  C CB  . ASP A 1 335 ? 19.927  13.642  13.890  1.00 50.85  ? 335 ASP A CB  1 
ATOM   2690  C CG  . ASP A 1 335 ? 20.690  12.963  12.759  1.00 53.55  ? 335 ASP A CG  1 
ATOM   2691  O OD1 . ASP A 1 335 ? 20.553  11.733  12.634  1.00 59.74  ? 335 ASP A OD1 1 
ATOM   2692  O OD2 . ASP A 1 335 ? 21.429  13.652  12.013  1.00 53.59  ? 335 ASP A OD2 1 
ATOM   2693  N N   . PHE A 1 336 ? 21.455  15.843  15.589  1.00 52.46  ? 336 PHE A N   1 
ATOM   2694  C CA  . PHE A 1 336 ? 22.442  16.912  15.607  1.00 44.76  ? 336 PHE A CA  1 
ATOM   2695  C C   . PHE A 1 336 ? 23.464  16.646  16.712  1.00 45.98  ? 336 PHE A C   1 
ATOM   2696  O O   . PHE A 1 336 ? 24.656  16.736  16.450  1.00 48.29  ? 336 PHE A O   1 
ATOM   2697  C CB  . PHE A 1 336 ? 21.826  18.306  15.768  1.00 41.27  ? 336 PHE A CB  1 
ATOM   2698  C CG  . PHE A 1 336 ? 22.841  19.424  15.604  1.00 40.17  ? 336 PHE A CG  1 
ATOM   2699  C CD1 . PHE A 1 336 ? 23.622  19.846  16.678  1.00 39.99  ? 336 PHE A CD1 1 
ATOM   2700  C CD2 . PHE A 1 336 ? 23.047  20.026  14.367  1.00 40.77  ? 336 PHE A CD2 1 
ATOM   2701  C CE1 . PHE A 1 336 ? 24.576  20.844  16.518  1.00 38.13  ? 336 PHE A CE1 1 
ATOM   2702  C CE2 . PHE A 1 336 ? 23.998  21.036  14.214  1.00 41.47  ? 336 PHE A CE2 1 
ATOM   2703  C CZ  . PHE A 1 336 ? 24.757  21.442  15.288  1.00 38.76  ? 336 PHE A CZ  1 
ATOM   2704  N N   . ALA A 1 337 ? 23.008  16.313  17.928  1.00 47.60  ? 337 ALA A N   1 
ATOM   2705  C CA  . ALA A 1 337 ? 23.900  16.031  19.048  1.00 48.80  ? 337 ALA A CA  1 
ATOM   2706  C C   . ALA A 1 337 ? 24.815  14.829  18.770  1.00 56.28  ? 337 ALA A C   1 
ATOM   2707  O O   . ALA A 1 337 ? 26.032  14.956  18.882  1.00 60.01  ? 337 ALA A O   1 
ATOM   2708  C CB  . ALA A 1 337 ? 23.092  15.838  20.306  1.00 48.78  ? 337 ALA A CB  1 
ATOM   2709  N N   . LEU A 1 338 ? 24.245  13.677  18.372  1.00 63.18  ? 338 LEU A N   1 
ATOM   2710  C CA  . LEU A 1 338 ? 25.011  12.456  18.117  1.00 62.11  ? 338 LEU A CA  1 
ATOM   2711  C C   . LEU A 1 338 ? 26.101  12.699  17.071  1.00 61.49  ? 338 LEU A C   1 
ATOM   2712  O O   . LEU A 1 338 ? 27.135  12.025  17.055  1.00 56.95  ? 338 LEU A O   1 
ATOM   2713  C CB  . LEU A 1 338 ? 24.095  11.317  17.664  1.00 62.59  ? 338 LEU A CB  1 
ATOM   2714  C CG  . LEU A 1 338 ? 23.046  10.826  18.672  1.00 72.78  ? 338 LEU A CG  1 
ATOM   2715  C CD1 . LEU A 1 338 ? 21.968  9.962   17.998  1.00 71.23  ? 338 LEU A CD1 1 
ATOM   2716  C CD2 . LEU A 1 338 ? 23.697  10.060  19.819  1.00 71.36  ? 338 LEU A CD2 1 
ATOM   2717  N N   . LYS A 1 339 ? 25.858  13.650  16.171  1.00 59.61  ? 339 LYS A N   1 
ATOM   2718  C CA  . LYS A 1 339 ? 26.800  13.909  15.100  1.00 63.56  ? 339 LYS A CA  1 
ATOM   2719  C C   . LYS A 1 339 ? 27.813  14.983  15.528  1.00 59.11  ? 339 LYS A C   1 
ATOM   2720  O O   . LYS A 1 339 ? 28.969  14.918  15.123  1.00 62.97  ? 339 LYS A O   1 
ATOM   2721  C CB  . LYS A 1 339 ? 25.926  14.174  13.867  1.00 71.85  ? 339 LYS A CB  1 
ATOM   2722  C CG  . LYS A 1 339 ? 26.573  13.984  12.503  1.00 84.66  ? 339 LYS A CG  1 
ATOM   2723  C CD  . LYS A 1 339 ? 25.674  14.478  11.372  1.00 92.52  ? 339 LYS A CD  1 
ATOM   2724  C CE  . LYS A 1 339 ? 26.429  14.911  10.155  1.00 93.96  ? 339 LYS A CE  1 
ATOM   2725  N NZ  . LYS A 1 339 ? 25.495  15.577  9.247   1.00 95.77  ? 339 LYS A NZ  1 
ATOM   2726  N N   . HIS A 1 340 ? 27.417  15.947  16.378  1.00 55.76  ? 340 HIS A N   1 
ATOM   2727  C CA  . HIS A 1 340 ? 28.233  17.137  16.621  1.00 52.42  ? 340 HIS A CA  1 
ATOM   2728  C C   . HIS A 1 340 ? 28.752  17.239  18.061  1.00 51.31  ? 340 HIS A C   1 
ATOM   2729  O O   . HIS A 1 340 ? 29.773  17.883  18.271  1.00 45.70  ? 340 HIS A O   1 
ATOM   2730  C CB  . HIS A 1 340 ? 27.517  18.434  16.206  1.00 46.21  ? 340 HIS A CB  1 
ATOM   2731  C CG  . HIS A 1 340 ? 27.328  18.610  14.728  1.00 46.43  ? 340 HIS A CG  1 
ATOM   2732  N ND1 . HIS A 1 340 ? 26.104  18.452  14.108  1.00 47.38  ? 340 HIS A ND1 1 
ATOM   2733  C CD2 . HIS A 1 340 ? 28.179  18.963  13.748  1.00 50.34  ? 340 HIS A CD2 1 
ATOM   2734  C CE1 . HIS A 1 340 ? 26.221  18.684  12.799  1.00 48.64  ? 340 HIS A CE1 1 
ATOM   2735  N NE2 . HIS A 1 340 ? 27.473  18.994  12.554  1.00 50.81  ? 340 HIS A NE2 1 
ATOM   2736  N N   . LEU A 1 341 ? 28.079  16.636  19.053  1.00 49.71  ? 341 LEU A N   1 
ATOM   2737  C CA  . LEU A 1 341 ? 28.550  16.723  20.429  1.00 47.82  ? 341 LEU A CA  1 
ATOM   2738  C C   . LEU A 1 341 ? 28.154  15.490  21.243  1.00 49.99  ? 341 LEU A C   1 
ATOM   2739  O O   . LEU A 1 341 ? 27.455  15.615  22.249  1.00 48.42  ? 341 LEU A O   1 
ATOM   2740  C CB  . LEU A 1 341 ? 27.981  17.988  21.061  1.00 50.91  ? 341 LEU A CB  1 
ATOM   2741  C CG  . LEU A 1 341 ? 26.452  18.111  21.043  1.00 53.08  ? 341 LEU A CG  1 
ATOM   2742  C CD1 . LEU A 1 341 ? 25.937  18.464  22.435  1.00 54.13  ? 341 LEU A CD1 1 
ATOM   2743  C CD2 . LEU A 1 341 ? 25.964  19.133  20.018  1.00 53.74  ? 341 LEU A CD2 1 
ATOM   2744  N N   . PRO A 1 342 ? 28.619  14.268  20.884  1.00 56.19  ? 342 PRO A N   1 
ATOM   2745  C CA  . PRO A 1 342 ? 28.142  13.048  21.543  1.00 58.22  ? 342 PRO A CA  1 
ATOM   2746  C C   . PRO A 1 342 ? 28.609  12.871  22.981  1.00 60.95  ? 342 PRO A C   1 
ATOM   2747  O O   . PRO A 1 342 ? 27.926  12.199  23.746  1.00 72.83  ? 342 PRO A O   1 
ATOM   2748  C CB  . PRO A 1 342 ? 28.647  11.901  20.643  1.00 62.11  ? 342 PRO A CB  1 
ATOM   2749  C CG  . PRO A 1 342 ? 29.842  12.488  19.903  1.00 57.94  ? 342 PRO A CG  1 
ATOM   2750  C CD  . PRO A 1 342 ? 29.607  13.995  19.825  1.00 57.92  ? 342 PRO A CD  1 
ATOM   2751  N N   . ASP A 1 343 ? 29.758  13.470  23.337  1.00 67.09  ? 343 ASP A N   1 
ATOM   2752  C CA  . ASP A 1 343 ? 30.385  13.267  24.642  1.00 66.82  ? 343 ASP A CA  1 
ATOM   2753  C C   . ASP A 1 343 ? 30.015  14.376  25.628  1.00 67.44  ? 343 ASP A C   1 
ATOM   2754  O O   . ASP A 1 343 ? 30.521  14.385  26.760  1.00 65.46  ? 343 ASP A O   1 
ATOM   2755  C CB  . ASP A 1 343 ? 31.902  13.171  24.550  1.00 62.73  ? 343 ASP A CB  1 
ATOM   2756  C CG  . ASP A 1 343 ? 32.439  12.067  23.654  1.00 63.96  ? 343 ASP A CG  1 
ATOM   2757  O OD1 . ASP A 1 343 ? 31.917  10.939  23.736  1.00 67.19  ? 343 ASP A OD1 1 
ATOM   2758  O OD2 . ASP A 1 343 ? 33.378  12.346  22.890  1.00 65.06  ? 343 ASP A OD2 1 
ATOM   2759  N N   . ASP A 1 344 ? 29.147  15.308  25.196  1.00 61.15  ? 344 ASP A N   1 
ATOM   2760  C CA  . ASP A 1 344 ? 28.697  16.389  26.060  1.00 55.88  ? 344 ASP A CA  1 
ATOM   2761  C C   . ASP A 1 344 ? 27.893  15.747  27.179  1.00 56.89  ? 344 ASP A C   1 
ATOM   2762  O O   . ASP A 1 344 ? 27.026  14.918  26.914  1.00 58.78  ? 344 ASP A O   1 
ATOM   2763  C CB  . ASP A 1 344 ? 27.942  17.455  25.281  1.00 56.91  ? 344 ASP A CB  1 
ATOM   2764  C CG  . ASP A 1 344 ? 27.455  18.662  26.071  1.00 46.08  ? 344 ASP A CG  1 
ATOM   2765  O OD1 . ASP A 1 344 ? 26.454  18.534  26.786  1.00 40.25  ? 344 ASP A OD1 1 
ATOM   2766  O OD2 . ASP A 1 344 ? 28.074  19.724  25.945  1.00 45.10  ? 344 ASP A OD2 1 
ATOM   2767  N N   . GLU A 1 345 ? 28.232  16.094  28.421  1.00 59.95  ? 345 GLU A N   1 
ATOM   2768  C CA  . GLU A 1 345 ? 27.735  15.353  29.565  1.00 64.06  ? 345 GLU A CA  1 
ATOM   2769  C C   . GLU A 1 345 ? 26.234  15.572  29.740  1.00 63.93  ? 345 GLU A C   1 
ATOM   2770  O O   . GLU A 1 345 ? 25.534  14.639  30.145  1.00 63.98  ? 345 GLU A O   1 
ATOM   2771  C CB  . GLU A 1 345 ? 28.553  15.671  30.817  1.00 70.09  ? 345 GLU A CB  1 
ATOM   2772  C CG  . GLU A 1 345 ? 29.983  15.135  30.730  1.00 76.01  ? 345 GLU A CG  1 
ATOM   2773  C CD  . GLU A 1 345 ? 30.430  14.329  31.945  1.00 78.24  ? 345 GLU A CD  1 
ATOM   2774  O OE1 . GLU A 1 345 ? 30.334  13.080  31.846  1.00 81.10  ? 345 GLU A OE1 1 
ATOM   2775  O OE2 . GLU A 1 345 ? 30.864  14.914  32.968  1.00 63.98  ? 345 GLU A OE2 1 
ATOM   2776  N N   . LEU A 1 346 ? 25.760  16.796  29.444  1.00 63.38  ? 346 LEU A N   1 
ATOM   2777  C CA  . LEU A 1 346 ? 24.353  17.148  29.591  1.00 59.70  ? 346 LEU A CA  1 
ATOM   2778  C C   . LEU A 1 346 ? 23.551  16.484  28.470  1.00 56.92  ? 346 LEU A C   1 
ATOM   2779  O O   . LEU A 1 346 ? 22.387  16.162  28.657  1.00 51.13  ? 346 LEU A O   1 
ATOM   2780  C CB  . LEU A 1 346 ? 24.092  18.655  29.584  1.00 57.06  ? 346 LEU A CB  1 
ATOM   2781  C CG  . LEU A 1 346 ? 24.783  19.513  30.648  1.00 59.78  ? 346 LEU A CG  1 
ATOM   2782  C CD1 . LEU A 1 346 ? 24.239  20.930  30.529  1.00 57.90  ? 346 LEU A CD1 1 
ATOM   2783  C CD2 . LEU A 1 346 ? 24.635  19.007  32.084  1.00 63.59  ? 346 LEU A CD2 1 
ATOM   2784  N N   . PHE A 1 347 ? 24.149  16.327  27.283  1.00 61.24  ? 347 PHE A N   1 
ATOM   2785  C CA  . PHE A 1 347 ? 23.493  15.586  26.214  1.00 63.30  ? 347 PHE A CA  1 
ATOM   2786  C C   . PHE A 1 347 ? 23.294  14.144  26.682  1.00 63.82  ? 347 PHE A C   1 
ATOM   2787  O O   . PHE A 1 347 ? 22.212  13.585  26.515  1.00 61.12  ? 347 PHE A O   1 
ATOM   2788  C CB  . PHE A 1 347 ? 24.221  15.568  24.863  1.00 58.71  ? 347 PHE A CB  1 
ATOM   2789  C CG  . PHE A 1 347 ? 23.650  14.530  23.898  1.00 56.58  ? 347 PHE A CG  1 
ATOM   2790  C CD1 . PHE A 1 347 ? 22.284  14.458  23.642  1.00 50.87  ? 347 PHE A CD1 1 
ATOM   2791  C CD2 . PHE A 1 347 ? 24.476  13.579  23.302  1.00 57.32  ? 347 PHE A CD2 1 
ATOM   2792  C CE1 . PHE A 1 347 ? 21.771  13.494  22.783  1.00 52.39  ? 347 PHE A CE1 1 
ATOM   2793  C CE2 . PHE A 1 347 ? 23.954  12.608  22.458  1.00 53.60  ? 347 PHE A CE2 1 
ATOM   2794  C CZ  . PHE A 1 347 ? 22.607  12.570  22.194  1.00 53.79  ? 347 PHE A CZ  1 
ATOM   2795  N N   . LYS A 1 348 ? 24.340  13.571  27.293  1.00 69.15  ? 348 LYS A N   1 
ATOM   2796  C CA  . LYS A 1 348 ? 24.342  12.169  27.684  1.00 77.52  ? 348 LYS A CA  1 
ATOM   2797  C C   . LYS A 1 348 ? 23.170  11.868  28.621  1.00 79.85  ? 348 LYS A C   1 
ATOM   2798  O O   . LYS A 1 348 ? 22.670  10.743  28.604  1.00 86.18  ? 348 LYS A O   1 
ATOM   2799  C CB  . LYS A 1 348 ? 25.726  11.721  28.186  1.00 81.02  ? 348 LYS A CB  1 
ATOM   2800  C CG  . LYS A 1 348 ? 26.627  11.217  27.036  1.00 88.53  ? 348 LYS A CG  1 
ATOM   2801  C CD  . LYS A 1 348 ? 27.992  10.606  27.350  1.00 90.42  ? 348 LYS A CD  1 
ATOM   2802  C CE  . LYS A 1 348 ? 28.534  9.837   26.166  1.00 91.68  ? 348 LYS A CE  1 
ATOM   2803  N NZ  . LYS A 1 348 ? 29.984  9.633   26.234  1.00 92.60  ? 348 LYS A NZ  1 
ATOM   2804  N N   . ILE A 1 349 ? 22.703  12.884  29.371  1.00 76.19  ? 349 ILE A N   1 
ATOM   2805  C CA  . ILE A 1 349 ? 21.538  12.766  30.241  1.00 69.12  ? 349 ILE A CA  1 
ATOM   2806  C C   . ILE A 1 349 ? 20.225  12.829  29.446  1.00 82.17  ? 349 ILE A C   1 
ATOM   2807  O O   . ILE A 1 349 ? 19.239  12.173  29.813  1.00 85.80  ? 349 ILE A O   1 
ATOM   2808  C CB  . ILE A 1 349 ? 21.594  13.835  31.347  1.00 67.65  ? 349 ILE A CB  1 
ATOM   2809  C CG1 . ILE A 1 349 ? 22.869  13.676  32.195  1.00 82.09  ? 349 ILE A CG1 1 
ATOM   2810  C CG2 . ILE A 1 349 ? 20.331  13.808  32.210  1.00 67.28  ? 349 ILE A CG2 1 
ATOM   2811  C CD1 . ILE A 1 349 ? 22.903  14.508  33.471  1.00 83.15  ? 349 ILE A CD1 1 
ATOM   2812  N N   . VAL A 1 350 ? 20.185  13.648  28.383  1.00 83.69  ? 350 VAL A N   1 
ATOM   2813  C CA  . VAL A 1 350 ? 18.986  13.759  27.562  1.00 86.79  ? 350 VAL A CA  1 
ATOM   2814  C C   . VAL A 1 350 ? 18.872  12.486  26.719  1.00 81.21  ? 350 VAL A C   1 
ATOM   2815  O O   . VAL A 1 350 ? 17.763  12.063  26.389  1.00 71.90  ? 350 VAL A O   1 
ATOM   2816  C CB  . VAL A 1 350 ? 18.970  15.050  26.710  1.00 81.51  ? 350 VAL A CB  1 
ATOM   2817  C CG1 . VAL A 1 350 ? 17.914  15.010  25.610  1.00 81.20  ? 350 VAL A CG1 1 
ATOM   2818  C CG2 . VAL A 1 350 ? 18.777  16.296  27.574  1.00 74.96  ? 350 VAL A CG2 1 
ATOM   2819  N N   . SER A 1 351 ? 20.038  11.880  26.433  1.00 77.02  ? 351 SER A N   1 
ATOM   2820  C CA  . SER A 1 351 ? 20.187  10.661  25.645  1.00 81.03  ? 351 SER A CA  1 
ATOM   2821  C C   . SER A 1 351 ? 19.775  9.427   26.452  1.00 86.50  ? 351 SER A C   1 
ATOM   2822  O O   . SER A 1 351 ? 19.235  8.461   25.905  1.00 80.90  ? 351 SER A O   1 
ATOM   2823  C CB  . SER A 1 351 ? 21.624  10.544  25.166  1.00 71.76  ? 351 SER A CB  1 
ATOM   2824  O OG  . SER A 1 351 ? 21.772  9.587   24.131  1.00 62.37  ? 351 SER A OG  1 
ATOM   2825  N N   . LEU A 1 352 ? 20.075  9.466   27.756  1.00 91.36  ? 352 LEU A N   1 
ATOM   2826  C CA  . LEU A 1 352 ? 19.615  8.473   28.714  1.00 96.53  ? 352 LEU A CA  1 
ATOM   2827  C C   . LEU A 1 352 ? 18.127  8.685   29.009  1.00 98.40  ? 352 LEU A C   1 
ATOM   2828  O O   . LEU A 1 352 ? 17.412  7.700   29.192  1.00 110.90 ? 352 LEU A O   1 
ATOM   2829  C CB  . LEU A 1 352 ? 20.470  8.577   29.980  1.00 95.89  ? 352 LEU A CB  1 
ATOM   2830  C CG  . LEU A 1 352 ? 20.352  7.445   31.008  1.00 89.24  ? 352 LEU A CG  1 
ATOM   2831  C CD1 . LEU A 1 352 ? 21.103  6.195   30.566  1.00 86.51  ? 352 LEU A CD1 1 
ATOM   2832  C CD2 . LEU A 1 352 ? 20.859  7.921   32.355  1.00 89.14  ? 352 LEU A CD2 1 
ATOM   2833  N N   . CYS A 1 353 ? 17.673  9.957   29.049  1.00 86.69  ? 353 CYS A N   1 
ATOM   2834  C CA  . CYS A 1 353 ? 16.283  10.300  29.348  1.00 86.92  ? 353 CYS A CA  1 
ATOM   2835  C C   . CYS A 1 353 ? 15.320  9.767   28.273  1.00 92.82  ? 353 CYS A C   1 
ATOM   2836  O O   . CYS A 1 353 ? 14.148  9.528   28.575  1.00 84.60  ? 353 CYS A O   1 
ATOM   2837  C CB  . CYS A 1 353 ? 16.086  11.806  29.538  1.00 81.26  ? 353 CYS A CB  1 
ATOM   2838  S SG  . CYS A 1 353 ? 16.176  12.389  31.253  1.00 66.16  ? 353 CYS A SG  1 
ATOM   2839  N N   . TYR A 1 354 ? 15.817  9.588   27.031  1.00 90.13  ? 354 TYR A N   1 
ATOM   2840  C CA  . TYR A 1 354 ? 15.035  9.132   25.884  1.00 92.51  ? 354 TYR A CA  1 
ATOM   2841  C C   . TYR A 1 354 ? 14.734  7.636   25.968  1.00 107.43 ? 354 TYR A C   1 
ATOM   2842  O O   . TYR A 1 354 ? 13.711  7.185   25.449  1.00 106.08 ? 354 TYR A O   1 
ATOM   2843  C CB  . TYR A 1 354 ? 15.831  9.359   24.593  1.00 89.59  ? 354 TYR A CB  1 
ATOM   2844  C CG  . TYR A 1 354 ? 15.111  9.195   23.257  1.00 74.69  ? 354 TYR A CG  1 
ATOM   2845  C CD1 . TYR A 1 354 ? 13.802  9.637   23.077  1.00 72.87  ? 354 TYR A CD1 1 
ATOM   2846  C CD2 . TYR A 1 354 ? 15.765  8.633   22.162  1.00 68.29  ? 354 TYR A CD2 1 
ATOM   2847  C CE1 . TYR A 1 354 ? 13.165  9.520   21.852  1.00 69.12  ? 354 TYR A CE1 1 
ATOM   2848  C CE2 . TYR A 1 354 ? 15.138  8.502   20.934  1.00 68.26  ? 354 TYR A CE2 1 
ATOM   2849  C CZ  . TYR A 1 354 ? 13.835  8.949   20.782  1.00 70.72  ? 354 TYR A CZ  1 
ATOM   2850  O OH  . TYR A 1 354 ? 13.203  8.830   19.580  1.00 70.49  ? 354 TYR A OH  1 
ATOM   2851  N N   . GLU A 1 355 ? 15.666  6.888   26.582  1.00 114.76 ? 355 GLU A N   1 
ATOM   2852  C CA  . GLU A 1 355 ? 15.596  5.438   26.714  1.00 107.89 ? 355 GLU A CA  1 
ATOM   2853  C C   . GLU A 1 355 ? 14.804  5.029   27.957  1.00 100.13 ? 355 GLU A C   1 
ATOM   2854  O O   . GLU A 1 355 ? 14.131  3.998   27.948  1.00 96.36  ? 355 GLU A O   1 
ATOM   2855  C CB  . GLU A 1 355 ? 17.011  4.866   26.806  1.00 103.73 ? 355 GLU A CB  1 
ATOM   2856  C CG  . GLU A 1 355 ? 17.840  5.082   25.541  1.00 110.50 ? 355 GLU A CG  1 
ATOM   2857  C CD  . GLU A 1 355 ? 19.308  4.711   25.692  1.00 114.82 ? 355 GLU A CD  1 
ATOM   2858  O OE1 . GLU A 1 355 ? 20.001  4.542   24.666  1.00 112.28 ? 355 GLU A OE1 1 
ATOM   2859  O OE2 . GLU A 1 355 ? 19.768  4.600   26.846  1.00 114.16 ? 355 GLU A OE2 1 
ATOM   2860  N N   . VAL A 1 356 ? 14.883  5.839   29.021  1.00 94.90  ? 356 VAL A N   1 
ATOM   2861  C CA  . VAL A 1 356 ? 14.378  5.444   30.325  1.00 97.81  ? 356 VAL A CA  1 
ATOM   2862  C C   . VAL A 1 356 ? 12.988  6.025   30.576  1.00 100.42 ? 356 VAL A C   1 
ATOM   2863  O O   . VAL A 1 356 ? 12.113  5.299   31.044  1.00 114.53 ? 356 VAL A O   1 
ATOM   2864  C CB  . VAL A 1 356 ? 15.356  5.841   31.448  1.00 97.90  ? 356 VAL A CB  1 
ATOM   2865  C CG1 . VAL A 1 356 ? 14.729  5.675   32.831  1.00 99.46  ? 356 VAL A CG1 1 
ATOM   2866  C CG2 . VAL A 1 356 ? 16.671  5.071   31.345  1.00 91.67  ? 356 VAL A CG2 1 
ATOM   2867  N N   . ILE A 1 357 ? 12.794  7.321   30.296  1.00 98.24  ? 357 ILE A N   1 
ATOM   2868  C CA  . ILE A 1 357 ? 11.600  8.026   30.740  1.00 108.00 ? 357 ILE A CA  1 
ATOM   2869  C C   . ILE A 1 357 ? 10.345  7.551   29.990  1.00 125.67 ? 357 ILE A C   1 
ATOM   2870  O O   . ILE A 1 357 ? 9.254   7.603   30.562  1.00 133.17 ? 357 ILE A O   1 
ATOM   2871  C CB  . ILE A 1 357 ? 11.795  9.555   30.656  1.00 103.07 ? 357 ILE A CB  1 
ATOM   2872  C CG1 . ILE A 1 357 ? 12.971  10.028  31.506  1.00 95.23  ? 357 ILE A CG1 1 
ATOM   2873  C CG2 . ILE A 1 357 ? 10.514  10.300  31.037  1.00 103.23 ? 357 ILE A CG2 1 
ATOM   2874  C CD1 . ILE A 1 357 ? 12.843  9.687   32.979  1.00 94.12  ? 357 ILE A CD1 1 
ATOM   2875  N N   . PRO A 1 358 ? 10.398  7.113   28.704  1.00 130.30 ? 358 PRO A N   1 
ATOM   2876  C CA  . PRO A 1 358 ? 9.206   6.565   28.042  1.00 131.68 ? 358 PRO A CA  1 
ATOM   2877  C C   . PRO A 1 358 ? 8.572   5.325   28.678  1.00 125.96 ? 358 PRO A C   1 
ATOM   2878  O O   . PRO A 1 358 ? 7.348   5.230   28.734  1.00 112.11 ? 358 PRO A O   1 
ATOM   2879  C CB  . PRO A 1 358 ? 9.702   6.281   26.607  1.00 134.87 ? 358 PRO A CB  1 
ATOM   2880  C CG  . PRO A 1 358 ? 10.845  7.244   26.419  1.00 132.53 ? 358 PRO A CG  1 
ATOM   2881  C CD  . PRO A 1 358 ? 11.535  7.244   27.777  1.00 129.52 ? 358 PRO A CD  1 
ATOM   2882  N N   . GLU A 1 359 ? 9.403   4.381   29.145  1.00 128.45 ? 359 GLU A N   1 
ATOM   2883  C CA  . GLU A 1 359 ? 8.929   3.178   29.822  1.00 125.25 ? 359 GLU A CA  1 
ATOM   2884  C C   . GLU A 1 359 ? 8.318   3.530   31.183  1.00 124.33 ? 359 GLU A C   1 
ATOM   2885  O O   . GLU A 1 359 ? 7.369   2.877   31.618  1.00 126.88 ? 359 GLU A O   1 
ATOM   2886  C CB  . GLU A 1 359 ? 10.071  2.172   29.976  1.00 115.45 ? 359 GLU A CB  1 
ATOM   2887  C CG  . GLU A 1 359 ? 10.597  1.635   28.646  1.00 112.72 ? 359 GLU A CG  1 
ATOM   2888  C CD  . GLU A 1 359 ? 11.994  1.035   28.707  1.00 108.81 ? 359 GLU A CD  1 
ATOM   2889  O OE1 . GLU A 1 359 ? 12.529  0.883   29.828  1.00 107.13 ? 359 GLU A OE1 1 
ATOM   2890  O OE2 . GLU A 1 359 ? 12.561  0.737   27.632  1.00 94.12  ? 359 GLU A OE2 1 
ATOM   2891  N N   . VAL A 1 360 ? 8.863   4.574   31.833  1.00 120.61 ? 360 VAL A N   1 
ATOM   2892  C CA  . VAL A 1 360 ? 8.465   5.019   33.166  1.00 118.77 ? 360 VAL A CA  1 
ATOM   2893  C C   . VAL A 1 360 ? 7.168   5.831   33.127  1.00 117.89 ? 360 VAL A C   1 
ATOM   2894  O O   . VAL A 1 360 ? 6.500   5.961   34.156  1.00 105.39 ? 360 VAL A O   1 
ATOM   2895  C CB  . VAL A 1 360 ? 9.581   5.859   33.825  1.00 112.99 ? 360 VAL A CB  1 
ATOM   2896  C CG1 . VAL A 1 360 ? 9.083   6.630   35.047  1.00 114.14 ? 360 VAL A CG1 1 
ATOM   2897  C CG2 . VAL A 1 360 ? 10.803  5.016   34.174  1.00 101.93 ? 360 VAL A CG2 1 
ATOM   2898  N N   . LEU A 1 361 ? 6.862   6.441   31.971  1.00 124.96 ? 361 LEU A N   1 
ATOM   2899  C CA  . LEU A 1 361 ? 5.617   7.179   31.792  1.00 125.36 ? 361 LEU A CA  1 
ATOM   2900  C C   . LEU A 1 361 ? 4.538   6.282   31.169  1.00 139.92 ? 361 LEU A C   1 
ATOM   2901  O O   . LEU A 1 361 ? 3.360   6.643   31.188  1.00 125.40 ? 361 LEU A O   1 
ATOM   2902  C CB  . LEU A 1 361 ? 5.859   8.452   30.977  1.00 107.59 ? 361 LEU A CB  1 
ATOM   2903  C CG  . LEU A 1 361 ? 6.353   9.676   31.757  1.00 98.71  ? 361 LEU A CG  1 
ATOM   2904  C CD1 . LEU A 1 361 ? 6.726   10.774  30.776  1.00 97.33  ? 361 LEU A CD1 1 
ATOM   2905  C CD2 . LEU A 1 361 ? 5.339   10.201  32.775  1.00 93.99  ? 361 LEU A CD2 1 
ATOM   2906  N N   . LYS A 1 362 ? 4.935   5.114   30.632  1.00 146.42 ? 362 LYS A N   1 
ATOM   2907  C CA  . LYS A 1 362 ? 3.994   4.063   30.260  1.00 141.53 ? 362 LYS A CA  1 
ATOM   2908  C C   . LYS A 1 362 ? 3.407   3.417   31.516  1.00 148.13 ? 362 LYS A C   1 
ATOM   2909  O O   . LYS A 1 362 ? 2.192   3.448   31.712  1.00 149.91 ? 362 LYS A O   1 
ATOM   2910  C CB  . LYS A 1 362 ? 4.638   2.998   29.364  1.00 135.19 ? 362 LYS A CB  1 
ATOM   2911  C CG  . LYS A 1 362 ? 4.524   3.320   27.893  1.00 134.45 ? 362 LYS A CG  1 
ATOM   2912  C CD  . LYS A 1 362 ? 5.410   2.476   26.993  1.00 140.03 ? 362 LYS A CD  1 
ATOM   2913  C CE  . LYS A 1 362 ? 5.207   2.905   25.577  1.00 150.02 ? 362 LYS A CE  1 
ATOM   2914  N NZ  . LYS A 1 362 ? 6.209   2.333   24.679  1.00 155.00 ? 362 LYS A NZ  1 
ATOM   2915  N N   . LYS A 1 363 ? 4.279   2.852   32.365  1.00 134.31 ? 363 LYS A N   1 
ATOM   2916  C CA  . LYS A 1 363 ? 3.853   2.088   33.531  1.00 123.69 ? 363 LYS A CA  1 
ATOM   2917  C C   . LYS A 1 363 ? 3.103   2.979   34.530  1.00 126.55 ? 363 LYS A C   1 
ATOM   2918  O O   . LYS A 1 363 ? 2.195   2.505   35.212  1.00 123.79 ? 363 LYS A O   1 
ATOM   2919  C CB  . LYS A 1 363 ? 5.058   1.298   34.061  1.00 114.02 ? 363 LYS A CB  1 
ATOM   2920  C CG  . LYS A 1 363 ? 5.477   0.202   33.095  1.00 114.94 ? 363 LYS A CG  1 
ATOM   2921  C CD  . LYS A 1 363 ? 6.952   -0.169  33.087  1.00 117.85 ? 363 LYS A CD  1 
ATOM   2922  C CE  . LYS A 1 363 ? 7.299   -0.863  31.805  1.00 118.92 ? 363 LYS A CE  1 
ATOM   2923  N NZ  . LYS A 1 363 ? 8.695   -1.299  31.798  1.00 122.20 ? 363 LYS A NZ  1 
ATOM   2924  N N   . HIS A 1 364 ? 3.463   4.267   34.614  1.00 127.36 ? 364 HIS A N   1 
ATOM   2925  C CA  . HIS A 1 364 ? 2.575   5.271   35.190  1.00 128.95 ? 364 HIS A CA  1 
ATOM   2926  C C   . HIS A 1 364 ? 1.377   5.457   34.250  1.00 126.51 ? 364 HIS A C   1 
ATOM   2927  O O   . HIS A 1 364 ? 0.251   5.117   34.671  1.00 121.80 ? 364 HIS A O   1 
ATOM   2928  C CB  . HIS A 1 364 ? 3.295   6.609   35.422  1.00 129.56 ? 364 HIS A CB  1 
ATOM   2929  C CG  . HIS A 1 364 ? 2.406   7.795   35.682  1.00 119.77 ? 364 HIS A CG  1 
ATOM   2930  N ND1 . HIS A 1 364 ? 2.138   8.763   34.731  1.00 119.51 ? 364 HIS A ND1 1 
ATOM   2931  C CD2 . HIS A 1 364 ? 1.770   8.189   36.798  1.00 108.18 ? 364 HIS A CD2 1 
ATOM   2932  C CE1 . HIS A 1 364 ? 1.351   9.692   35.257  1.00 121.10 ? 364 HIS A CE1 1 
ATOM   2933  N NE2 . HIS A 1 364 ? 1.115   9.363   36.513  1.00 119.53 ? 364 HIS A NE2 1 
ATOM   2934  N N   . PRO A 1 370 ? 3.648   9.476   25.658  1.00 93.21  ? 370 PRO A N   1 
ATOM   2935  C CA  . PRO A 1 370 ? 4.726   9.021   26.532  1.00 100.44 ? 370 PRO A CA  1 
ATOM   2936  C C   . PRO A 1 370 ? 6.127   9.308   25.985  1.00 94.88  ? 370 PRO A C   1 
ATOM   2937  O O   . PRO A 1 370 ? 7.118   8.655   26.337  1.00 81.07  ? 370 PRO A O   1 
ATOM   2938  C CB  . PRO A 1 370 ? 4.430   7.512   26.654  1.00 104.91 ? 370 PRO A CB  1 
ATOM   2939  C CG  . PRO A 1 370 ? 3.863   7.138   25.308  1.00 101.80 ? 370 PRO A CG  1 
ATOM   2940  C CD  . PRO A 1 370 ? 3.022   8.352   24.949  1.00 101.31 ? 370 PRO A CD  1 
ATOM   2941  N N   . TRP A 1 371 ? 6.199   10.331  25.135  1.00 81.88  ? 371 TRP A N   1 
ATOM   2942  C CA  . TRP A 1 371 ? 7.404   10.591  24.375  1.00 83.11  ? 371 TRP A CA  1 
ATOM   2943  C C   . TRP A 1 371 ? 7.777   12.071  24.504  1.00 81.03  ? 371 TRP A C   1 
ATOM   2944  O O   . TRP A 1 371 ? 6.967   12.876  24.989  1.00 66.52  ? 371 TRP A O   1 
ATOM   2945  C CB  . TRP A 1 371 ? 7.173   10.136  22.927  1.00 87.37  ? 371 TRP A CB  1 
ATOM   2946  C CG  . TRP A 1 371 ? 6.909   8.656   22.790  1.00 93.13  ? 371 TRP A CG  1 
ATOM   2947  C CD1 . TRP A 1 371 ? 5.696   8.033   22.681  1.00 89.77  ? 371 TRP A CD1 1 
ATOM   2948  C CD2 . TRP A 1 371 ? 7.902   7.606   22.734  1.00 100.06 ? 371 TRP A CD2 1 
ATOM   2949  N NE1 . TRP A 1 371 ? 5.858   6.676   22.563  1.00 89.85  ? 371 TRP A NE1 1 
ATOM   2950  C CE2 . TRP A 1 371 ? 7.201   6.384   22.589  1.00 103.20 ? 371 TRP A CE2 1 
ATOM   2951  C CE3 . TRP A 1 371 ? 9.304   7.577   22.792  1.00 99.70  ? 371 TRP A CE3 1 
ATOM   2952  C CZ2 . TRP A 1 371 ? 7.866   5.159   22.499  1.00 105.13 ? 371 TRP A CZ2 1 
ATOM   2953  C CZ3 . TRP A 1 371 ? 9.957   6.364   22.696  1.00 102.65 ? 371 TRP A CZ3 1 
ATOM   2954  C CH2 . TRP A 1 371 ? 9.246   5.172   22.547  1.00 100.79 ? 371 TRP A CH2 1 
ATOM   2955  N N   . PRO A 1 372 ? 9.034   12.459  24.148  1.00 72.23  ? 372 PRO A N   1 
ATOM   2956  C CA  . PRO A 1 372 ? 9.472   13.857  24.267  1.00 63.16  ? 372 PRO A CA  1 
ATOM   2957  C C   . PRO A 1 372 ? 9.019   14.819  23.159  1.00 60.73  ? 372 PRO A C   1 
ATOM   2958  O O   . PRO A 1 372 ? 8.756   14.406  22.021  1.00 54.15  ? 372 PRO A O   1 
ATOM   2959  C CB  . PRO A 1 372 ? 11.004  13.702  24.308  1.00 60.62  ? 372 PRO A CB  1 
ATOM   2960  C CG  . PRO A 1 372 ? 11.294  12.476  23.455  1.00 64.50  ? 372 PRO A CG  1 
ATOM   2961  C CD  . PRO A 1 372 ? 10.098  11.562  23.652  1.00 65.98  ? 372 PRO A CD  1 
ATOM   2962  N N   . ASN A 1 373 ? 8.932   16.107  23.535  1.00 60.45  ? 373 ASN A N   1 
ATOM   2963  C CA  . ASN A 1 373 ? 8.675   17.212  22.623  1.00 64.41  ? 373 ASN A CA  1 
ATOM   2964  C C   . ASN A 1 373 ? 10.003  17.904  22.296  1.00 70.24  ? 373 ASN A C   1 
ATOM   2965  O O   . ASN A 1 373 ? 11.074  17.398  22.645  1.00 64.44  ? 373 ASN A O   1 
ATOM   2966  C CB  . ASN A 1 373 ? 7.598   18.141  23.183  1.00 59.14  ? 373 ASN A CB  1 
ATOM   2967  C CG  . ASN A 1 373 ? 8.108   19.039  24.285  1.00 65.77  ? 373 ASN A CG  1 
ATOM   2968  O OD1 . ASN A 1 373 ? 8.964   19.892  24.034  1.00 73.31  ? 373 ASN A OD1 1 
ATOM   2969  N ND2 . ASN A 1 373 ? 7.586   18.898  25.497  1.00 67.33  ? 373 ASN A ND2 1 
ATOM   2970  N N   . VAL A 1 374 ? 9.908   19.061  21.619  1.00 70.84  ? 374 VAL A N   1 
ATOM   2971  C CA  . VAL A 1 374 ? 11.052  19.766  21.052  1.00 65.30  ? 374 VAL A CA  1 
ATOM   2972  C C   . VAL A 1 374 ? 11.900  20.400  22.153  1.00 65.23  ? 374 VAL A C   1 
ATOM   2973  O O   . VAL A 1 374 ? 13.123  20.438  22.028  1.00 66.14  ? 374 VAL A O   1 
ATOM   2974  C CB  . VAL A 1 374 ? 10.619  20.847  20.038  1.00 64.92  ? 374 VAL A CB  1 
ATOM   2975  C CG1 . VAL A 1 374 ? 9.728   21.932  20.651  1.00 59.40  ? 374 VAL A CG1 1 
ATOM   2976  C CG2 . VAL A 1 374 ? 11.828  21.481  19.358  1.00 66.96  ? 374 VAL A CG2 1 
ATOM   2977  N N   . ASP A 1 375 ? 11.241  20.909  23.206  1.00 62.98  ? 375 ASP A N   1 
ATOM   2978  C CA  . ASP A 1 375 ? 11.873  21.757  24.215  1.00 63.56  ? 375 ASP A CA  1 
ATOM   2979  C C   . ASP A 1 375 ? 12.761  20.930  25.161  1.00 58.11  ? 375 ASP A C   1 
ATOM   2980  O O   . ASP A 1 375 ? 13.545  21.475  25.941  1.00 46.75  ? 375 ASP A O   1 
ATOM   2981  C CB  . ASP A 1 375 ? 10.837  22.588  24.967  1.00 59.35  ? 375 ASP A CB  1 
ATOM   2982  C CG  . ASP A 1 375 ? 9.883   23.467  24.159  1.00 59.49  ? 375 ASP A CG  1 
ATOM   2983  O OD1 . ASP A 1 375 ? 10.311  24.560  23.675  1.00 55.73  ? 375 ASP A OD1 1 
ATOM   2984  O OD2 . ASP A 1 375 ? 8.696   23.068  24.050  1.00 54.29  ? 375 ASP A OD2 1 
ATOM   2985  N N   . ALA A 1 376 ? 12.659  19.601  25.063  1.00 62.17  ? 376 ALA A N   1 
ATOM   2986  C CA  . ALA A 1 376 ? 13.461  18.685  25.861  1.00 71.85  ? 376 ALA A CA  1 
ATOM   2987  C C   . ALA A 1 376 ? 14.928  18.668  25.430  1.00 66.29  ? 376 ALA A C   1 
ATOM   2988  O O   . ALA A 1 376 ? 15.783  18.148  26.160  1.00 69.75  ? 376 ALA A O   1 
ATOM   2989  C CB  . ALA A 1 376 ? 12.881  17.284  25.767  1.00 74.44  ? 376 ALA A CB  1 
ATOM   2990  N N   . HIS A 1 377 ? 15.192  19.180  24.218  1.00 56.56  ? 377 HIS A N   1 
ATOM   2991  C CA  . HIS A 1 377 ? 16.454  18.922  23.541  1.00 50.70  ? 377 HIS A CA  1 
ATOM   2992  C C   . HIS A 1 377 ? 17.180  20.211  23.143  1.00 43.22  ? 377 HIS A C   1 
ATOM   2993  O O   . HIS A 1 377 ? 18.379  20.173  22.912  1.00 44.30  ? 377 HIS A O   1 
ATOM   2994  C CB  . HIS A 1 377 ? 16.209  17.984  22.353  1.00 44.36  ? 377 HIS A CB  1 
ATOM   2995  C CG  . HIS A 1 377 ? 17.300  17.001  22.152  1.00 46.27  ? 377 HIS A CG  1 
ATOM   2996  N ND1 . HIS A 1 377 ? 18.633  17.321  22.257  1.00 47.09  ? 377 HIS A ND1 1 
ATOM   2997  C CD2 . HIS A 1 377 ? 17.257  15.708  21.842  1.00 50.73  ? 377 HIS A CD2 1 
ATOM   2998  C CE1 . HIS A 1 377 ? 19.355  16.244  21.992  1.00 48.15  ? 377 HIS A CE1 1 
ATOM   2999  N NE2 . HIS A 1 377 ? 18.539  15.254  21.741  1.00 51.43  ? 377 HIS A NE2 1 
ATOM   3000  N N   . SER A 1 378 ? 16.475  21.342  23.053  1.00 39.99  ? 378 SER A N   1 
ATOM   3001  C CA  . SER A 1 378 ? 17.059  22.521  22.443  1.00 40.89  ? 378 SER A CA  1 
ATOM   3002  C C   . SER A 1 378 ? 18.040  23.172  23.405  1.00 40.27  ? 378 SER A C   1 
ATOM   3003  O O   . SER A 1 378 ? 19.058  23.709  22.983  1.00 40.97  ? 378 SER A O   1 
ATOM   3004  C CB  . SER A 1 378 ? 16.010  23.481  21.996  1.00 40.64  ? 378 SER A CB  1 
ATOM   3005  O OG  . SER A 1 378 ? 15.195  23.809  23.103  1.00 45.16  ? 378 SER A OG  1 
ATOM   3006  N N   . GLY A 1 379 ? 17.725  23.114  24.700  1.00 45.75  ? 379 GLY A N   1 
ATOM   3007  C CA  . GLY A 1 379 ? 18.535  23.766  25.717  1.00 42.11  ? 379 GLY A CA  1 
ATOM   3008  C C   . GLY A 1 379 ? 19.994  23.323  25.644  1.00 38.40  ? 379 GLY A C   1 
ATOM   3009  O O   . GLY A 1 379 ? 20.914  24.142  25.716  1.00 31.92  ? 379 GLY A O   1 
ATOM   3010  N N   . VAL A 1 380 ? 20.183  22.014  25.510  1.00 38.08  ? 380 VAL A N   1 
ATOM   3011  C CA  . VAL A 1 380 ? 21.496  21.442  25.703  1.00 45.58  ? 380 VAL A CA  1 
ATOM   3012  C C   . VAL A 1 380 ? 22.345  21.796  24.495  1.00 41.25  ? 380 VAL A C   1 
ATOM   3013  O O   . VAL A 1 380 ? 23.550  21.973  24.627  1.00 43.55  ? 380 VAL A O   1 
ATOM   3014  C CB  . VAL A 1 380 ? 21.477  19.924  25.962  1.00 51.89  ? 380 VAL A CB  1 
ATOM   3015  C CG1 . VAL A 1 380 ? 20.729  19.604  27.251  1.00 56.29  ? 380 VAL A CG1 1 
ATOM   3016  C CG2 . VAL A 1 380 ? 20.907  19.149  24.778  1.00 53.39  ? 380 VAL A CG2 1 
ATOM   3017  N N   . LEU A 1 381 ? 21.700  21.927  23.337  1.00 41.16  ? 381 LEU A N   1 
ATOM   3018  C CA  . LEU A 1 381 ? 22.421  22.265  22.121  1.00 38.18  ? 381 LEU A CA  1 
ATOM   3019  C C   . LEU A 1 381 ? 23.012  23.667  22.266  1.00 37.13  ? 381 LEU A C   1 
ATOM   3020  O O   . LEU A 1 381 ? 24.217  23.854  22.094  1.00 33.73  ? 381 LEU A O   1 
ATOM   3021  C CB  . LEU A 1 381 ? 21.497  22.158  20.914  1.00 37.34  ? 381 LEU A CB  1 
ATOM   3022  C CG  . LEU A 1 381 ? 20.867  20.786  20.664  1.00 38.61  ? 381 LEU A CG  1 
ATOM   3023  C CD1 . LEU A 1 381 ? 20.048  20.847  19.383  1.00 38.83  ? 381 LEU A CD1 1 
ATOM   3024  C CD2 . LEU A 1 381 ? 21.900  19.662  20.604  1.00 40.47  ? 381 LEU A CD2 1 
ATOM   3025  N N   . LEU A 1 382 ? 22.151  24.628  22.624  1.00 33.25  ? 382 LEU A N   1 
ATOM   3026  C CA  . LEU A 1 382 ? 22.560  26.004  22.859  1.00 35.94  ? 382 LEU A CA  1 
ATOM   3027  C C   . LEU A 1 382 ? 23.650  26.107  23.929  1.00 38.45  ? 382 LEU A C   1 
ATOM   3028  O O   . LEU A 1 382 ? 24.630  26.839  23.745  1.00 38.78  ? 382 LEU A O   1 
ATOM   3029  C CB  . LEU A 1 382 ? 21.327  26.804  23.266  1.00 37.02  ? 382 LEU A CB  1 
ATOM   3030  C CG  . LEU A 1 382 ? 20.249  26.910  22.186  1.00 38.99  ? 382 LEU A CG  1 
ATOM   3031  C CD1 . LEU A 1 382 ? 18.987  27.464  22.772  1.00 42.01  ? 382 LEU A CD1 1 
ATOM   3032  C CD2 . LEU A 1 382 ? 20.690  27.750  20.995  1.00 37.46  ? 382 LEU A CD2 1 
ATOM   3033  N N   . TRP A 1 383 ? 23.447  25.425  25.067  1.00 38.02  ? 383 TRP A N   1 
ATOM   3034  C CA  . TRP A 1 383 ? 24.352  25.552  26.199  1.00 40.51  ? 383 TRP A CA  1 
ATOM   3035  C C   . TRP A 1 383 ? 25.742  25.070  25.802  1.00 39.42  ? 383 TRP A C   1 
ATOM   3036  O O   . TRP A 1 383 ? 26.735  25.686  26.175  1.00 35.83  ? 383 TRP A O   1 
ATOM   3037  C CB  . TRP A 1 383 ? 23.816  24.768  27.402  1.00 43.53  ? 383 TRP A CB  1 
ATOM   3038  C CG  . TRP A 1 383 ? 24.639  24.874  28.660  1.00 42.10  ? 383 TRP A CG  1 
ATOM   3039  C CD1 . TRP A 1 383 ? 25.712  24.100  28.994  1.00 41.79  ? 383 TRP A CD1 1 
ATOM   3040  C CD2 . TRP A 1 383 ? 24.433  25.769  29.777  1.00 37.40  ? 383 TRP A CD2 1 
ATOM   3041  N NE1 . TRP A 1 383 ? 26.194  24.456  30.229  1.00 39.16  ? 383 TRP A NE1 1 
ATOM   3042  C CE2 . TRP A 1 383 ? 25.434  25.472  30.734  1.00 38.13  ? 383 TRP A CE2 1 
ATOM   3043  C CE3 . TRP A 1 383 ? 23.515  26.782  30.064  1.00 35.44  ? 383 TRP A CE3 1 
ATOM   3044  C CZ2 . TRP A 1 383 ? 25.545  26.160  31.945  1.00 39.36  ? 383 TRP A CZ2 1 
ATOM   3045  C CZ3 . TRP A 1 383 ? 23.620  27.464  31.260  1.00 36.54  ? 383 TRP A CZ3 1 
ATOM   3046  C CH2 . TRP A 1 383 ? 24.619  27.153  32.191  1.00 39.37  ? 383 TRP A CH2 1 
ATOM   3047  N N   . HIS A 1 384 ? 25.776  23.994  25.000  1.00 37.85  ? 384 HIS A N   1 
ATOM   3048  C CA  . HIS A 1 384 ? 27.014  23.353  24.608  1.00 33.07  ? 384 HIS A CA  1 
ATOM   3049  C C   . HIS A 1 384 ? 27.938  24.341  23.918  1.00 30.42  ? 384 HIS A C   1 
ATOM   3050  O O   . HIS A 1 384 ? 29.145  24.251  24.071  1.00 30.45  ? 384 HIS A O   1 
ATOM   3051  C CB  . HIS A 1 384 ? 26.781  22.173  23.659  1.00 34.63  ? 384 HIS A CB  1 
ATOM   3052  C CG  . HIS A 1 384 ? 28.057  21.566  23.136  1.00 36.92  ? 384 HIS A CG  1 
ATOM   3053  N ND1 . HIS A 1 384 ? 28.912  20.800  23.903  1.00 34.07  ? 384 HIS A ND1 1 
ATOM   3054  C CD2 . HIS A 1 384 ? 28.627  21.653  21.922  1.00 35.29  ? 384 HIS A CD2 1 
ATOM   3055  C CE1 . HIS A 1 384 ? 29.946  20.438  23.160  1.00 36.67  ? 384 HIS A CE1 1 
ATOM   3056  N NE2 . HIS A 1 384 ? 29.786  20.936  21.957  1.00 33.83  ? 384 HIS A NE2 1 
ATOM   3057  N N   . TYR A 1 385 ? 27.378  25.250  23.135  1.00 28.75  ? 385 TYR A N   1 
ATOM   3058  C CA  . TYR A 1 385 ? 28.176  26.138  22.309  1.00 30.78  ? 385 TYR A CA  1 
ATOM   3059  C C   . TYR A 1 385 ? 28.333  27.494  22.981  1.00 30.50  ? 385 TYR A C   1 
ATOM   3060  O O   . TYR A 1 385 ? 28.785  28.443  22.350  1.00 36.13  ? 385 TYR A O   1 
ATOM   3061  C CB  . TYR A 1 385 ? 27.514  26.310  20.940  1.00 32.79  ? 385 TYR A CB  1 
ATOM   3062  C CG  . TYR A 1 385 ? 27.614  25.054  20.101  1.00 34.00  ? 385 TYR A CG  1 
ATOM   3063  C CD1 . TYR A 1 385 ? 28.814  24.719  19.485  1.00 31.47  ? 385 TYR A CD1 1 
ATOM   3064  C CD2 . TYR A 1 385 ? 26.526  24.213  19.942  1.00 33.90  ? 385 TYR A CD2 1 
ATOM   3065  C CE1 . TYR A 1 385 ? 28.932  23.572  18.729  1.00 34.41  ? 385 TYR A CE1 1 
ATOM   3066  C CE2 . TYR A 1 385 ? 26.634  23.058  19.186  1.00 37.94  ? 385 TYR A CE2 1 
ATOM   3067  C CZ  . TYR A 1 385 ? 27.837  22.734  18.576  1.00 37.50  ? 385 TYR A CZ  1 
ATOM   3068  O OH  . TYR A 1 385 ? 27.946  21.588  17.823  1.00 37.20  ? 385 TYR A OH  1 
ATOM   3069  N N   . GLY A 1 386 ? 27.922  27.594  24.239  1.00 32.68  ? 386 GLY A N   1 
ATOM   3070  C CA  . GLY A 1 386 ? 28.152  28.799  25.023  1.00 35.66  ? 386 GLY A CA  1 
ATOM   3071  C C   . GLY A 1 386 ? 27.027  29.832  24.953  1.00 33.58  ? 386 GLY A C   1 
ATOM   3072  O O   . GLY A 1 386 ? 27.254  30.962  25.339  1.00 32.31  ? 386 GLY A O   1 
ATOM   3073  N N   . ILE A 1 387 ? 25.845  29.473  24.428  1.00 38.94  ? 387 ILE A N   1 
ATOM   3074  C CA  . ILE A 1 387 ? 24.648  30.288  24.604  1.00 37.02  ? 387 ILE A CA  1 
ATOM   3075  C C   . ILE A 1 387 ? 23.956  29.810  25.886  1.00 32.57  ? 387 ILE A C   1 
ATOM   3076  O O   . ILE A 1 387 ? 23.269  28.792  25.852  1.00 29.39  ? 387 ILE A O   1 
ATOM   3077  C CB  . ILE A 1 387 ? 23.731  30.229  23.360  1.00 35.73  ? 387 ILE A CB  1 
ATOM   3078  C CG1 . ILE A 1 387 ? 24.445  30.718  22.080  1.00 38.13  ? 387 ILE A CG1 1 
ATOM   3079  C CG2 . ILE A 1 387 ? 22.445  31.025  23.585  1.00 34.00  ? 387 ILE A CG2 1 
ATOM   3080  C CD1 . ILE A 1 387 ? 24.734  29.634  21.066  1.00 39.86  ? 387 ILE A CD1 1 
ATOM   3081  N N   . ARG A 1 388 ? 24.167  30.532  27.006  1.00 31.49  ? 388 ARG A N   1 
ATOM   3082  C CA  . ARG A 1 388 ? 23.865  30.024  28.343  1.00 33.47  ? 388 ARG A CA  1 
ATOM   3083  C C   . ARG A 1 388 ? 22.811  30.861  29.069  1.00 32.21  ? 388 ARG A C   1 
ATOM   3084  O O   . ARG A 1 388 ? 22.465  30.541  30.207  1.00 32.00  ? 388 ARG A O   1 
ATOM   3085  C CB  . ARG A 1 388 ? 25.113  29.950  29.236  1.00 40.28  ? 388 ARG A CB  1 
ATOM   3086  C CG  . ARG A 1 388 ? 26.218  29.040  28.729  1.00 46.97  ? 388 ARG A CG  1 
ATOM   3087  C CD  . ARG A 1 388 ? 27.407  28.861  29.672  1.00 59.19  ? 388 ARG A CD  1 
ATOM   3088  N NE  . ARG A 1 388 ? 28.320  27.944  28.973  1.00 77.00  ? 388 ARG A NE  1 
ATOM   3089  C CZ  . ARG A 1 388 ? 28.791  26.758  29.370  1.00 79.41  ? 388 ARG A CZ  1 
ATOM   3090  N NH1 . ARG A 1 388 ? 28.870  26.443  30.657  1.00 85.39  ? 388 ARG A NH1 1 
ATOM   3091  N NH2 . ARG A 1 388 ? 29.258  25.919  28.457  1.00 66.51  ? 388 ARG A NH2 1 
ATOM   3092  N N   . GLU A 1 389 ? 22.256  31.870  28.377  1.00 30.82  ? 389 GLU A N   1 
ATOM   3093  C CA  . GLU A 1 389 ? 21.334  32.837  28.943  1.00 30.67  ? 389 GLU A CA  1 
ATOM   3094  C C   . GLU A 1 389 ? 19.882  32.376  28.775  1.00 33.83  ? 389 GLU A C   1 
ATOM   3095  O O   . GLU A 1 389 ? 19.198  32.762  27.822  1.00 32.89  ? 389 GLU A O   1 
ATOM   3096  C CB  . GLU A 1 389 ? 21.598  34.158  28.221  1.00 33.35  ? 389 GLU A CB  1 
ATOM   3097  C CG  . GLU A 1 389 ? 22.994  34.735  28.454  1.00 32.10  ? 389 GLU A CG  1 
ATOM   3098  C CD  . GLU A 1 389 ? 24.145  34.120  27.687  1.00 30.98  ? 389 GLU A CD  1 
ATOM   3099  O OE1 . GLU A 1 389 ? 25.257  34.259  28.233  1.00 32.15  ? 389 GLU A OE1 1 
ATOM   3100  O OE2 . GLU A 1 389 ? 23.971  33.523  26.600  1.00 27.23  ? 389 GLU A OE2 1 
ATOM   3101  N N   . TYR A 1 390 ? 19.404  31.563  29.730  1.00 35.12  ? 390 TYR A N   1 
ATOM   3102  C CA  . TYR A 1 390 ? 18.121  30.873  29.641  1.00 35.63  ? 390 TYR A CA  1 
ATOM   3103  C C   . TYR A 1 390 ? 17.007  31.790  29.111  1.00 35.70  ? 390 TYR A C   1 
ATOM   3104  O O   . TYR A 1 390 ? 16.254  31.408  28.220  1.00 35.86  ? 390 TYR A O   1 
ATOM   3105  C CB  . TYR A 1 390 ? 17.694  30.350  31.022  1.00 38.70  ? 390 TYR A CB  1 
ATOM   3106  C CG  . TYR A 1 390 ? 18.731  29.538  31.781  1.00 46.13  ? 390 TYR A CG  1 
ATOM   3107  C CD1 . TYR A 1 390 ? 18.977  28.207  31.458  1.00 47.34  ? 390 TYR A CD1 1 
ATOM   3108  C CD2 . TYR A 1 390 ? 19.482  30.109  32.812  1.00 54.81  ? 390 TYR A CD2 1 
ATOM   3109  C CE1 . TYR A 1 390 ? 19.932  27.470  32.140  1.00 49.97  ? 390 TYR A CE1 1 
ATOM   3110  C CE2 . TYR A 1 390 ? 20.433  29.378  33.508  1.00 55.25  ? 390 TYR A CE2 1 
ATOM   3111  C CZ  . TYR A 1 390 ? 20.655  28.047  33.176  1.00 55.25  ? 390 TYR A CZ  1 
ATOM   3112  O OH  . TYR A 1 390 ? 21.594  27.301  33.855  1.00 57.85  ? 390 TYR A OH  1 
ATOM   3113  N N   . ASP A 1 391 ? 16.867  32.985  29.693  1.00 34.42  ? 391 ASP A N   1 
ATOM   3114  C CA  . ASP A 1 391 ? 15.773  33.889  29.386  1.00 35.73  ? 391 ASP A CA  1 
ATOM   3115  C C   . ASP A 1 391 ? 15.729  34.283  27.907  1.00 36.02  ? 391 ASP A C   1 
ATOM   3116  O O   . ASP A 1 391 ? 14.645  34.522  27.348  1.00 36.37  ? 391 ASP A O   1 
ATOM   3117  C CB  . ASP A 1 391 ? 15.941  35.160  30.189  1.00 41.02  ? 391 ASP A CB  1 
ATOM   3118  C CG  . ASP A 1 391 ? 15.605  35.041  31.660  1.00 37.46  ? 391 ASP A CG  1 
ATOM   3119  O OD1 . ASP A 1 391 ? 15.085  33.995  32.049  1.00 33.81  ? 391 ASP A OD1 1 
ATOM   3120  O OD2 . ASP A 1 391 ? 15.867  36.011  32.376  1.00 42.70  ? 391 ASP A OD2 1 
ATOM   3121  N N   . PHE A 1 392 ? 16.913  34.345  27.288  1.00 28.03  ? 392 PHE A N   1 
ATOM   3122  C CA  . PHE A 1 392 ? 17.028  34.687  25.882  1.00 27.19  ? 392 PHE A CA  1 
ATOM   3123  C C   . PHE A 1 392 ? 16.582  33.539  24.978  1.00 25.41  ? 392 PHE A C   1 
ATOM   3124  O O   . PHE A 1 392 ? 16.305  33.759  23.810  1.00 23.69  ? 392 PHE A O   1 
ATOM   3125  C CB  . PHE A 1 392 ? 18.471  35.115  25.585  1.00 26.46  ? 392 PHE A CB  1 
ATOM   3126  C CG  . PHE A 1 392 ? 18.635  35.749  24.215  1.00 25.43  ? 392 PHE A CG  1 
ATOM   3127  C CD1 . PHE A 1 392 ? 18.262  37.065  23.995  1.00 25.37  ? 392 PHE A CD1 1 
ATOM   3128  C CD2 . PHE A 1 392 ? 19.131  35.022  23.143  1.00 27.44  ? 392 PHE A CD2 1 
ATOM   3129  C CE1 . PHE A 1 392 ? 18.386  37.642  22.748  1.00 23.94  ? 392 PHE A CE1 1 
ATOM   3130  C CE2 . PHE A 1 392 ? 19.252  35.609  21.895  1.00 24.97  ? 392 PHE A CE2 1 
ATOM   3131  C CZ  . PHE A 1 392 ? 18.887  36.916  21.711  1.00 24.35  ? 392 PHE A CZ  1 
ATOM   3132  N N   . TYR A 1 393 ? 16.508  32.306  25.489  1.00 27.57  ? 393 TYR A N   1 
ATOM   3133  C CA  . TYR A 1 393 ? 16.140  31.180  24.637  1.00 30.02  ? 393 TYR A CA  1 
ATOM   3134  C C   . TYR A 1 393 ? 14.795  31.401  23.931  1.00 31.18  ? 393 TYR A C   1 
ATOM   3135  O O   . TYR A 1 393 ? 14.590  30.915  22.823  1.00 30.04  ? 393 TYR A O   1 
ATOM   3136  C CB  . TYR A 1 393 ? 16.118  29.915  25.494  1.00 33.47  ? 393 TYR A CB  1 
ATOM   3137  C CG  . TYR A 1 393 ? 17.475  29.363  25.920  1.00 33.88  ? 393 TYR A CG  1 
ATOM   3138  C CD1 . TYR A 1 393 ? 18.646  30.083  25.770  1.00 34.61  ? 393 TYR A CD1 1 
ATOM   3139  C CD2 . TYR A 1 393 ? 17.567  28.103  26.488  1.00 36.13  ? 393 TYR A CD2 1 
ATOM   3140  C CE1 . TYR A 1 393 ? 19.873  29.557  26.140  1.00 36.17  ? 393 TYR A CE1 1 
ATOM   3141  C CE2 . TYR A 1 393 ? 18.778  27.571  26.884  1.00 36.80  ? 393 TYR A CE2 1 
ATOM   3142  C CZ  . TYR A 1 393 ? 19.941  28.298  26.704  1.00 37.13  ? 393 TYR A CZ  1 
ATOM   3143  O OH  . TYR A 1 393 ? 21.141  27.771  27.090  1.00 32.35  ? 393 TYR A OH  1 
ATOM   3144  N N   . THR A 1 394 ? 13.872  32.118  24.588  1.00 31.86  ? 394 THR A N   1 
ATOM   3145  C CA  . THR A 1 394 ? 12.538  32.355  24.062  1.00 32.36  ? 394 THR A CA  1 
ATOM   3146  C C   . THR A 1 394 ? 12.594  33.390  22.940  1.00 31.27  ? 394 THR A C   1 
ATOM   3147  O O   . THR A 1 394 ? 11.712  33.442  22.087  1.00 29.00  ? 394 THR A O   1 
ATOM   3148  C CB  . THR A 1 394 ? 11.595  32.808  25.176  1.00 32.22  ? 394 THR A CB  1 
ATOM   3149  O OG1 . THR A 1 394 ? 11.752  31.899  26.250  1.00 32.92  ? 394 THR A OG1 1 
ATOM   3150  C CG2 . THR A 1 394 ? 10.132  32.713  24.791  1.00 35.28  ? 394 THR A CG2 1 
ATOM   3151  N N   . VAL A 1 395 ? 13.627  34.230  22.940  1.00 31.71  ? 395 VAL A N   1 
ATOM   3152  C CA  . VAL A 1 395 ? 13.783  35.198  21.869  1.00 29.12  ? 395 VAL A CA  1 
ATOM   3153  C C   . VAL A 1 395 ? 14.207  34.473  20.599  1.00 28.65  ? 395 VAL A C   1 
ATOM   3154  O O   . VAL A 1 395 ? 13.707  34.786  19.523  1.00 28.79  ? 395 VAL A O   1 
ATOM   3155  C CB  . VAL A 1 395 ? 14.744  36.330  22.263  1.00 27.96  ? 395 VAL A CB  1 
ATOM   3156  C CG1 . VAL A 1 395 ? 15.040  37.261  21.093  1.00 29.91  ? 395 VAL A CG1 1 
ATOM   3157  C CG2 . VAL A 1 395 ? 14.191  37.106  23.449  1.00 24.75  ? 395 VAL A CG2 1 
ATOM   3158  N N   . LEU A 1 396 ? 15.087  33.475  20.735  1.00 29.54  ? 396 LEU A N   1 
ATOM   3159  C CA  . LEU A 1 396 ? 15.442  32.620  19.610  1.00 29.60  ? 396 LEU A CA  1 
ATOM   3160  C C   . LEU A 1 396 ? 14.184  31.941  19.058  1.00 29.04  ? 396 LEU A C   1 
ATOM   3161  O O   . LEU A 1 396 ? 13.932  31.973  17.865  1.00 25.94  ? 396 LEU A O   1 
ATOM   3162  C CB  . LEU A 1 396 ? 16.510  31.608  20.026  1.00 32.00  ? 396 LEU A CB  1 
ATOM   3163  C CG  . LEU A 1 396 ? 17.812  32.205  20.582  1.00 32.39  ? 396 LEU A CG  1 
ATOM   3164  C CD1 . LEU A 1 396 ? 18.710  31.133  21.128  1.00 32.57  ? 396 LEU A CD1 1 
ATOM   3165  C CD2 . LEU A 1 396 ? 18.552  33.004  19.528  1.00 33.90  ? 396 LEU A CD2 1 
ATOM   3166  N N   . PHE A 1 397 ? 13.363  31.349  19.928  1.00 31.91  ? 397 PHE A N   1 
ATOM   3167  C CA  . PHE A 1 397 ? 12.099  30.756  19.504  1.00 30.39  ? 397 PHE A CA  1 
ATOM   3168  C C   . PHE A 1 397 ? 11.315  31.813  18.741  1.00 27.99  ? 397 PHE A C   1 
ATOM   3169  O O   . PHE A 1 397 ? 10.813  31.539  17.669  1.00 26.67  ? 397 PHE A O   1 
ATOM   3170  C CB  . PHE A 1 397 ? 11.315  30.248  20.723  1.00 32.32  ? 397 PHE A CB  1 
ATOM   3171  C CG  . PHE A 1 397 ? 10.179  29.265  20.469  1.00 31.84  ? 397 PHE A CG  1 
ATOM   3172  C CD1 . PHE A 1 397 ? 9.595   29.121  19.207  1.00 35.76  ? 397 PHE A CD1 1 
ATOM   3173  C CD2 . PHE A 1 397 ? 9.705   28.461  21.506  1.00 31.49  ? 397 PHE A CD2 1 
ATOM   3174  C CE1 . PHE A 1 397 ? 8.551   28.224  19.005  1.00 34.80  ? 397 PHE A CE1 1 
ATOM   3175  C CE2 . PHE A 1 397 ? 8.683   27.543  21.300  1.00 31.66  ? 397 PHE A CE2 1 
ATOM   3176  C CZ  . PHE A 1 397 ? 8.095   27.441  20.054  1.00 33.61  ? 397 PHE A CZ  1 
ATOM   3177  N N   . GLY A 1 398 ? 11.267  33.041  19.268  1.00 26.88  ? 398 GLY A N   1 
ATOM   3178  C CA  . GLY A 1 398 ? 10.511  34.102  18.624  1.00 27.09  ? 398 GLY A CA  1 
ATOM   3179  C C   . GLY A 1 398 ? 10.975  34.336  17.178  1.00 26.85  ? 398 GLY A C   1 
ATOM   3180  O O   . GLY A 1 398 ? 10.183  34.447  16.238  1.00 25.85  ? 398 GLY A O   1 
ATOM   3181  N N   . VAL A 1 399 ? 12.283  34.411  16.983  1.00 25.29  ? 399 VAL A N   1 
ATOM   3182  C CA  . VAL A 1 399 ? 12.793  34.805  15.685  1.00 26.48  ? 399 VAL A CA  1 
ATOM   3183  C C   . VAL A 1 399 ? 12.356  33.764  14.660  1.00 26.65  ? 399 VAL A C   1 
ATOM   3184  O O   . VAL A 1 399 ? 11.933  34.120  13.561  1.00 25.20  ? 399 VAL A O   1 
ATOM   3185  C CB  . VAL A 1 399 ? 14.320  34.969  15.760  1.00 28.84  ? 399 VAL A CB  1 
ATOM   3186  C CG1 . VAL A 1 399 ? 14.978  34.936  14.384  1.00 29.86  ? 399 VAL A CG1 1 
ATOM   3187  C CG2 . VAL A 1 399 ? 14.690  36.226  16.563  1.00 28.84  ? 399 VAL A CG2 1 
ATOM   3188  N N   . SER A 1 400 ? 12.424  32.494  15.069  1.00 26.53  ? 400 SER A N   1 
ATOM   3189  C CA  . SER A 1 400 ? 12.090  31.358  14.225  1.00 31.38  ? 400 SER A CA  1 
ATOM   3190  C C   . SER A 1 400 ? 10.599  31.351  13.880  1.00 34.39  ? 400 SER A C   1 
ATOM   3191  O O   . SER A 1 400 ? 10.214  31.122  12.733  1.00 36.03  ? 400 SER A O   1 
ATOM   3192  C CB  . SER A 1 400 ? 12.480  30.065  14.918  1.00 31.46  ? 400 SER A CB  1 
ATOM   3193  O OG  . SER A 1 400 ? 11.998  28.937  14.213  1.00 31.26  ? 400 SER A OG  1 
ATOM   3194  N N   . ARG A 1 401 ? 9.763   31.591  14.893  1.00 33.49  ? 401 ARG A N   1 
ATOM   3195  C CA  . ARG A 1 401 ? 8.326   31.470  14.741  1.00 31.95  ? 401 ARG A CA  1 
ATOM   3196  C C   . ARG A 1 401 ? 7.756   32.632  13.921  1.00 29.92  ? 401 ARG A C   1 
ATOM   3197  O O   . ARG A 1 401 ? 6.598   32.572  13.519  1.00 30.60  ? 401 ARG A O   1 
ATOM   3198  C CB  . ARG A 1 401 ? 7.773   31.348  16.164  1.00 33.11  ? 401 ARG A CB  1 
ATOM   3199  C CG  . ARG A 1 401 ? 6.270   31.113  16.245  1.00 35.45  ? 401 ARG A CG  1 
ATOM   3200  C CD  . ARG A 1 401 ? 5.719   30.006  15.347  1.00 35.17  ? 401 ARG A CD  1 
ATOM   3201  N NE  . ARG A 1 401 ? 6.133   28.638  15.674  1.00 32.97  ? 401 ARG A NE  1 
ATOM   3202  C CZ  . ARG A 1 401 ? 5.621   27.935  16.670  1.00 35.28  ? 401 ARG A CZ  1 
ATOM   3203  N NH1 . ARG A 1 401 ? 4.639   28.449  17.415  1.00 31.33  ? 401 ARG A NH1 1 
ATOM   3204  N NH2 . ARG A 1 401 ? 6.108   26.716  16.906  1.00 36.41  ? 401 ARG A NH2 1 
ATOM   3205  N N   . ALA A 1 402 ? 8.550   33.696  13.712  1.00 26.35  ? 402 ALA A N   1 
ATOM   3206  C CA  . ALA A 1 402 ? 8.194   34.770  12.798  1.00 26.53  ? 402 ALA A CA  1 
ATOM   3207  C C   . ALA A 1 402 ? 8.051   34.226  11.376  1.00 29.30  ? 402 ALA A C   1 
ATOM   3208  O O   . ALA A 1 402 ? 7.343   34.817  10.549  1.00 29.43  ? 402 ALA A O   1 
ATOM   3209  C CB  . ALA A 1 402 ? 9.212   35.907  12.832  1.00 22.46  ? 402 ALA A CB  1 
ATOM   3210  N N   . LEU A 1 403 ? 8.768   33.134  11.078  1.00 26.69  ? 403 LEU A N   1 
ATOM   3211  C CA  . LEU A 1 403 ? 8.709   32.580  9.741   1.00 29.65  ? 403 LEU A CA  1 
ATOM   3212  C C   . LEU A 1 403 ? 7.276   32.099  9.479   1.00 29.37  ? 403 LEU A C   1 
ATOM   3213  O O   . LEU A 1 403 ? 6.672   32.455  8.471   1.00 26.59  ? 403 LEU A O   1 
ATOM   3214  C CB  . LEU A 1 403 ? 9.749   31.477  9.530   1.00 28.77  ? 403 LEU A CB  1 
ATOM   3215  C CG  . LEU A 1 403 ? 11.217  31.889  9.671   1.00 30.72  ? 403 LEU A CG  1 
ATOM   3216  C CD1 . LEU A 1 403 ? 12.039  30.650  9.942   1.00 29.89  ? 403 LEU A CD1 1 
ATOM   3217  C CD2 . LEU A 1 403 ? 11.736  32.625  8.448   1.00 31.11  ? 403 LEU A CD2 1 
ATOM   3218  N N   . GLY A 1 404 ? 6.752   31.299  10.413  1.00 30.21  ? 404 GLY A N   1 
ATOM   3219  C CA  . GLY A 1 404 ? 5.406   30.768  10.329  1.00 32.02  ? 404 GLY A CA  1 
ATOM   3220  C C   . GLY A 1 404 ? 4.344   31.861  10.413  1.00 32.18  ? 404 GLY A C   1 
ATOM   3221  O O   . GLY A 1 404 ? 3.386   31.841  9.646   1.00 31.40  ? 404 GLY A O   1 
ATOM   3222  N N   . CYS A 1 405 ? 4.503   32.778  11.375  1.00 31.61  ? 405 CYS A N   1 
ATOM   3223  C CA  . CYS A 1 405 ? 3.502   33.801  11.622  1.00 31.59  ? 405 CYS A CA  1 
ATOM   3224  C C   . CYS A 1 405 ? 3.351   34.661  10.370  1.00 31.07  ? 405 CYS A C   1 
ATOM   3225  O O   . CYS A 1 405 ? 2.235   35.024  10.007  1.00 32.94  ? 405 CYS A O   1 
ATOM   3226  C CB  . CYS A 1 405 ? 3.786   34.597  12.901  1.00 31.23  ? 405 CYS A CB  1 
ATOM   3227  S SG  . CYS A 1 405 ? 3.601   33.658  14.452  1.00 27.72  ? 405 CYS A SG  1 
ATOM   3228  N N   . THR A 1 406 ? 4.459   34.984  9.698   1.00 29.93  ? 406 THR A N   1 
ATOM   3229  C CA  . THR A 1 406 ? 4.390   35.892  8.557   1.00 29.03  ? 406 THR A CA  1 
ATOM   3230  C C   . THR A 1 406 ? 3.735   35.196  7.361   1.00 28.05  ? 406 THR A C   1 
ATOM   3231  O O   . THR A 1 406 ? 2.938   35.800  6.635   1.00 28.64  ? 406 THR A O   1 
ATOM   3232  C CB  . THR A 1 406 ? 5.779   36.433  8.209   1.00 30.08  ? 406 THR A CB  1 
ATOM   3233  O OG1 . THR A 1 406 ? 6.652   35.304  8.099   1.00 29.38  ? 406 THR A OG1 1 
ATOM   3234  C CG2 . THR A 1 406 ? 6.247   37.459  9.231   1.00 28.78  ? 406 THR A CG2 1 
ATOM   3235  N N   . ALA A 1 407 ? 4.078   33.926  7.145   1.00 24.80  ? 407 ALA A N   1 
ATOM   3236  C CA  . ALA A 1 407 ? 3.479   33.176  6.060   1.00 27.79  ? 407 ALA A CA  1 
ATOM   3237  C C   . ALA A 1 407 ? 1.957   33.134  6.213   1.00 29.53  ? 407 ALA A C   1 
ATOM   3238  O O   . ALA A 1 407 ? 1.227   33.498  5.292   1.00 36.69  ? 407 ALA A O   1 
ATOM   3239  C CB  . ALA A 1 407 ? 4.092   31.790  5.997   1.00 29.24  ? 407 ALA A CB  1 
ATOM   3240  N N   . GLN A 1 408 ? 1.489   32.713  7.390   1.00 28.92  ? 408 GLN A N   1 
ATOM   3241  C CA  . GLN A 1 408 ? 0.070   32.591  7.697   1.00 28.74  ? 408 GLN A CA  1 
ATOM   3242  C C   . GLN A 1 408 ? -0.653  33.922  7.486   1.00 29.00  ? 408 GLN A C   1 
ATOM   3243  O O   . GLN A 1 408 ? -1.675  33.962  6.808   1.00 33.98  ? 408 GLN A O   1 
ATOM   3244  C CB  . GLN A 1 408 ? -0.132  32.068  9.125   1.00 29.21  ? 408 GLN A CB  1 
ATOM   3245  C CG  . GLN A 1 408 ? 0.349   30.635  9.343   1.00 29.05  ? 408 GLN A CG  1 
ATOM   3246  C CD  . GLN A 1 408 ? -0.046  30.094  10.692  1.00 30.00  ? 408 GLN A CD  1 
ATOM   3247  O OE1 . GLN A 1 408 ? -1.166  30.309  11.159  1.00 31.87  ? 408 GLN A OE1 1 
ATOM   3248  N NE2 . GLN A 1 408 ? 0.869   29.411  11.358  1.00 33.49  ? 408 GLN A NE2 1 
ATOM   3249  N N   . ALA A 1 409 ? -0.114  35.006  8.048   1.00 27.36  ? 409 ALA A N   1 
ATOM   3250  C CA  . ALA A 1 409 ? -0.716  36.324  7.923   1.00 28.93  ? 409 ALA A CA  1 
ATOM   3251  C C   . ALA A 1 409 ? -0.786  36.772  6.454   1.00 33.16  ? 409 ALA A C   1 
ATOM   3252  O O   . ALA A 1 409 ? -1.789  37.326  5.996   1.00 30.63  ? 409 ALA A O   1 
ATOM   3253  C CB  . ALA A 1 409 ? 0.048   37.311  8.784   1.00 28.44  ? 409 ALA A CB  1 
ATOM   3254  N N   . ILE A 1 410 ? 0.273   36.523  5.683   1.00 35.14  ? 410 ILE A N   1 
ATOM   3255  C CA  . ILE A 1 410 ? 0.222   36.806  4.257   1.00 35.66  ? 410 ILE A CA  1 
ATOM   3256  C C   . ILE A 1 410 ? -0.908  36.005  3.598   1.00 35.67  ? 410 ILE A C   1 
ATOM   3257  O O   . ILE A 1 410 ? -1.758  36.586  2.934   1.00 34.01  ? 410 ILE A O   1 
ATOM   3258  C CB  . ILE A 1 410 ? 1.590   36.545  3.606   1.00 34.38  ? 410 ILE A CB  1 
ATOM   3259  C CG1 . ILE A 1 410 ? 2.619   37.567  4.104   1.00 32.43  ? 410 ILE A CG1 1 
ATOM   3260  C CG2 . ILE A 1 410 ? 1.485   36.540  2.078   1.00 32.69  ? 410 ILE A CG2 1 
ATOM   3261  C CD1 . ILE A 1 410 ? 4.061   37.148  3.905   1.00 32.15  ? 410 ILE A CD1 1 
ATOM   3262  N N   . LEU A 1 411 ? -0.917  34.682  3.788   1.00 35.99  ? 411 LEU A N   1 
ATOM   3263  C CA  . LEU A 1 411 ? -1.841  33.802  3.078   1.00 35.90  ? 411 LEU A CA  1 
ATOM   3264  C C   . LEU A 1 411 ? -3.303  34.132  3.421   1.00 36.16  ? 411 LEU A C   1 
ATOM   3265  O O   . LEU A 1 411 ? -4.183  34.214  2.556   1.00 35.22  ? 411 LEU A O   1 
ATOM   3266  C CB  . LEU A 1 411 ? -1.509  32.351  3.445   1.00 32.31  ? 411 LEU A CB  1 
ATOM   3267  C CG  . LEU A 1 411 ? -0.235  31.765  2.845   1.00 31.57  ? 411 LEU A CG  1 
ATOM   3268  C CD1 . LEU A 1 411 ? 0.055   30.493  3.562   1.00 32.85  ? 411 LEU A CD1 1 
ATOM   3269  C CD2 . LEU A 1 411 ? -0.342  31.497  1.359   1.00 34.50  ? 411 LEU A CD2 1 
ATOM   3270  N N   . VAL A 1 412 ? -3.562  34.311  4.713   1.00 33.35  ? 412 VAL A N   1 
ATOM   3271  C CA  . VAL A 1 412 ? -4.911  34.546  5.179   1.00 33.49  ? 412 VAL A CA  1 
ATOM   3272  C C   . VAL A 1 412 ? -5.455  35.900  4.712   1.00 31.70  ? 412 VAL A C   1 
ATOM   3273  O O   . VAL A 1 412 ? -6.630  36.012  4.418   1.00 34.00  ? 412 VAL A O   1 
ATOM   3274  C CB  . VAL A 1 412 ? -4.814  34.363  6.697   1.00 35.78  ? 412 VAL A CB  1 
ATOM   3275  C CG1 . VAL A 1 412 ? -5.716  35.285  7.482   1.00 42.16  ? 412 VAL A CG1 1 
ATOM   3276  C CG2 . VAL A 1 412 ? -5.071  32.909  7.059   1.00 37.95  ? 412 VAL A CG2 1 
ATOM   3277  N N   . ARG A 1 413 ? -4.625  36.931  4.607   1.00 31.34  ? 413 ARG A N   1 
ATOM   3278  C CA  . ARG A 1 413 ? -5.069  38.199  4.053   1.00 32.26  ? 413 ARG A CA  1 
ATOM   3279  C C   . ARG A 1 413 ? -5.200  38.047  2.548   1.00 34.01  ? 413 ARG A C   1 
ATOM   3280  O O   . ARG A 1 413 ? -5.984  38.766  1.928   1.00 33.17  ? 413 ARG A O   1 
ATOM   3281  C CB  . ARG A 1 413 ? -4.138  39.376  4.376   1.00 33.11  ? 413 ARG A CB  1 
ATOM   3282  C CG  . ARG A 1 413 ? -4.053  39.664  5.869   1.00 35.14  ? 413 ARG A CG  1 
ATOM   3283  C CD  . ARG A 1 413 ? -5.051  40.708  6.330   1.00 36.49  ? 413 ARG A CD  1 
ATOM   3284  N NE  . ARG A 1 413 ? -6.423  40.359  5.952   1.00 40.34  ? 413 ARG A NE  1 
ATOM   3285  C CZ  . ARG A 1 413 ? -7.203  39.417  6.498   1.00 40.55  ? 413 ARG A CZ  1 
ATOM   3286  N NH1 . ARG A 1 413 ? -6.821  38.707  7.551   1.00 38.09  ? 413 ARG A NH1 1 
ATOM   3287  N NH2 . ARG A 1 413 ? -8.399  39.215  5.975   1.00 42.77  ? 413 ARG A NH2 1 
ATOM   3288  N N   . GLY A 1 414 ? -4.425  37.108  1.991   1.00 34.38  ? 414 GLY A N   1 
ATOM   3289  C CA  . GLY A 1 414 ? -4.565  36.712  0.599   1.00 34.50  ? 414 GLY A CA  1 
ATOM   3290  C C   . GLY A 1 414 ? -5.966  36.160  0.347   1.00 34.75  ? 414 GLY A C   1 
ATOM   3291  O O   . GLY A 1 414 ? -6.612  36.510  -0.640  1.00 30.92  ? 414 GLY A O   1 
ATOM   3292  N N   . TYR A 1 415 ? -6.398  35.288  1.263   1.00 35.42  ? 415 TYR A N   1 
ATOM   3293  C CA  . TYR A 1 415 ? -7.652  34.562  1.149   1.00 36.78  ? 415 TYR A CA  1 
ATOM   3294  C C   . TYR A 1 415 ? -8.825  35.480  1.487   1.00 38.69  ? 415 TYR A C   1 
ATOM   3295  O O   . TYR A 1 415 ? -9.946  35.179  1.098   1.00 38.55  ? 415 TYR A O   1 
ATOM   3296  C CB  . TYR A 1 415 ? -7.811  33.404  2.141   1.00 37.36  ? 415 TYR A CB  1 
ATOM   3297  C CG  . TYR A 1 415 ? -6.804  32.264  2.131   1.00 35.21  ? 415 TYR A CG  1 
ATOM   3298  C CD1 . TYR A 1 415 ? -5.889  32.101  1.104   1.00 35.46  ? 415 TYR A CD1 1 
ATOM   3299  C CD2 . TYR A 1 415 ? -6.808  31.315  3.146   1.00 36.36  ? 415 TYR A CD2 1 
ATOM   3300  C CE1 . TYR A 1 415 ? -5.003  31.032  1.090   1.00 34.71  ? 415 TYR A CE1 1 
ATOM   3301  C CE2 . TYR A 1 415 ? -5.937  30.232  3.130   1.00 37.25  ? 415 TYR A CE2 1 
ATOM   3302  C CZ  . TYR A 1 415 ? -5.020  30.091  2.103   1.00 33.45  ? 415 TYR A CZ  1 
ATOM   3303  O OH  . TYR A 1 415 ? -4.127  29.049  2.088   1.00 30.15  ? 415 TYR A OH  1 
ATOM   3304  N N   . MET A 1 416 ? -8.565  36.540  2.274   1.00 37.30  ? 416 MET A N   1 
ATOM   3305  C CA  . MET A 1 416 ? -9.573  37.491  2.740   1.00 35.64  ? 416 MET A CA  1 
ATOM   3306  C C   . MET A 1 416 ? -10.515 36.829  3.751   1.00 32.23  ? 416 MET A C   1 
ATOM   3307  O O   . MET A 1 416 ? -11.722 37.034  3.738   1.00 30.57  ? 416 MET A O   1 
ATOM   3308  C CB  . MET A 1 416 ? -10.328 38.115  1.560   1.00 38.43  ? 416 MET A CB  1 
ATOM   3309  C CG  . MET A 1 416 ? -9.409  38.731  0.499   1.00 43.64  ? 416 MET A CG  1 
ATOM   3310  S SD  . MET A 1 416 ? -10.357 39.475  -0.845  1.00 57.06  ? 416 MET A SD  1 
ATOM   3311  C CE  . MET A 1 416 ? -9.132  40.119  -1.995  1.00 63.88  ? 416 MET A CE  1 
ATOM   3312  N N   . LEU A 1 417 ? -9.942  36.045  4.667   1.00 32.85  ? 417 LEU A N   1 
ATOM   3313  C CA  . LEU A 1 417 ? -10.672 35.562  5.826   1.00 31.17  ? 417 LEU A CA  1 
ATOM   3314  C C   . LEU A 1 417 ? -11.082 36.758  6.686   1.00 30.42  ? 417 LEU A C   1 
ATOM   3315  O O   . LEU A 1 417 ? -10.358 37.735  6.809   1.00 25.99  ? 417 LEU A O   1 
ATOM   3316  C CB  . LEU A 1 417 ? -9.878  34.559  6.654   1.00 30.64  ? 417 LEU A CB  1 
ATOM   3317  C CG  . LEU A 1 417 ? -9.386  33.288  5.958   1.00 34.84  ? 417 LEU A CG  1 
ATOM   3318  C CD1 . LEU A 1 417 ? -8.921  32.243  7.007   1.00 35.26  ? 417 LEU A CD1 1 
ATOM   3319  C CD2 . LEU A 1 417 ? -10.419 32.701  5.010   1.00 36.02  ? 417 LEU A CD2 1 
ATOM   3320  N N   . PRO A 1 418 ? -12.298 36.744  7.268   1.00 33.88  ? 418 PRO A N   1 
ATOM   3321  C CA  . PRO A 1 418 ? -12.769 37.872  8.062   1.00 35.72  ? 418 PRO A CA  1 
ATOM   3322  C C   . PRO A 1 418 ? -12.265 37.807  9.503   1.00 31.01  ? 418 PRO A C   1 
ATOM   3323  O O   . PRO A 1 418 ? -11.496 36.920  9.854   1.00 32.38  ? 418 PRO A O   1 
ATOM   3324  C CB  . PRO A 1 418 ? -14.304 37.681  7.921   1.00 32.68  ? 418 PRO A CB  1 
ATOM   3325  C CG  . PRO A 1 418 ? -14.454 36.184  8.019   1.00 34.21  ? 418 PRO A CG  1 
ATOM   3326  C CD  . PRO A 1 418 ? -13.313 35.678  7.149   1.00 34.46  ? 418 PRO A CD  1 
ATOM   3327  N N   . ILE A 1 419 ? -12.767 38.752  10.302  1.00 31.61  ? 419 ILE A N   1 
ATOM   3328  C CA  . ILE A 1 419 ? -12.388 39.005  11.686  1.00 31.82  ? 419 ILE A CA  1 
ATOM   3329  C C   . ILE A 1 419 ? -12.724 37.807  12.575  1.00 30.89  ? 419 ILE A C   1 
ATOM   3330  O O   . ILE A 1 419 ? -13.688 37.084  12.347  1.00 34.30  ? 419 ILE A O   1 
ATOM   3331  C CB  . ILE A 1 419 ? -13.041 40.326  12.151  1.00 31.54  ? 419 ILE A CB  1 
ATOM   3332  C CG1 . ILE A 1 419 ? -12.471 40.812  13.484  1.00 38.83  ? 419 ILE A CG1 1 
ATOM   3333  C CG2 . ILE A 1 419 ? -14.564 40.248  12.202  1.00 28.89  ? 419 ILE A CG2 1 
ATOM   3334  C CD1 . ILE A 1 419 ? -12.804 42.260  13.802  1.00 41.05  ? 419 ILE A CD1 1 
ATOM   3335  N N   . GLU A 1 420 ? -11.862 37.553  13.557  1.00 30.52  ? 420 GLU A N   1 
ATOM   3336  C CA  . GLU A 1 420 ? -12.117 36.531  14.556  1.00 30.06  ? 420 GLU A CA  1 
ATOM   3337  C C   . GLU A 1 420 ? -12.997 37.136  15.651  1.00 31.35  ? 420 GLU A C   1 
ATOM   3338  O O   . GLU A 1 420 ? -12.607 38.116  16.290  1.00 30.79  ? 420 GLU A O   1 
ATOM   3339  C CB  . GLU A 1 420 ? -10.771 35.978  15.020  1.00 31.61  ? 420 GLU A CB  1 
ATOM   3340  C CG  . GLU A 1 420 ? -10.893 34.815  16.000  1.00 34.39  ? 420 GLU A CG  1 
ATOM   3341  C CD  . GLU A 1 420 ? -9.611  34.043  16.284  1.00 35.11  ? 420 GLU A CD  1 
ATOM   3342  O OE1 . GLU A 1 420 ? -9.596  33.334  17.306  1.00 30.00  ? 420 GLU A OE1 1 
ATOM   3343  O OE2 . GLU A 1 420 ? -8.660  34.111  15.470  1.00 36.28  ? 420 GLU A OE2 1 
ATOM   3344  N N   . ARG A 1 421 ? -14.221 36.597  15.800  1.00 36.30  ? 421 ARG A N   1 
ATOM   3345  C CA  . ARG A 1 421 ? -15.138 36.962  16.876  1.00 40.32  ? 421 ARG A CA  1 
ATOM   3346  C C   . ARG A 1 421 ? -15.942 35.734  17.282  1.00 36.27  ? 421 ARG A C   1 
ATOM   3347  O O   . ARG A 1 421 ? -17.107 35.605  16.938  1.00 39.30  ? 421 ARG A O   1 
ATOM   3348  C CB  . ARG A 1 421 ? -16.051 38.172  16.617  1.00 51.76  ? 421 ARG A CB  1 
ATOM   3349  C CG  . ARG A 1 421 ? -16.426 38.407  15.158  1.00 74.66  ? 421 ARG A CG  1 
ATOM   3350  C CD  . ARG A 1 421 ? -17.715 37.763  14.625  1.00 87.55  ? 421 ARG A CD  1 
ATOM   3351  N NE  . ARG A 1 421 ? -17.501 37.294  13.248  1.00 100.56 ? 421 ARG A NE  1 
ATOM   3352  C CZ  . ARG A 1 421 ? -17.593 37.975  12.099  1.00 97.33  ? 421 ARG A CZ  1 
ATOM   3353  N NH1 . ARG A 1 421 ? -16.984 37.485  11.027  1.00 87.81  ? 421 ARG A NH1 1 
ATOM   3354  N NH2 . ARG A 1 421 ? -18.216 39.148  12.034  1.00 88.35  ? 421 ARG A NH2 1 
ATOM   3355  N N   . PRO A 1 422 ? -15.375 34.784  18.059  1.00 38.40  ? 422 PRO A N   1 
ATOM   3356  C CA  . PRO A 1 422 ? -16.185 33.719  18.648  1.00 35.28  ? 422 PRO A CA  1 
ATOM   3357  C C   . PRO A 1 422 ? -17.160 34.362  19.618  1.00 32.97  ? 422 PRO A C   1 
ATOM   3358  O O   . PRO A 1 422 ? -17.090 35.554  19.880  1.00 35.87  ? 422 PRO A O   1 
ATOM   3359  C CB  . PRO A 1 422 ? -15.187 32.806  19.339  1.00 35.21  ? 422 PRO A CB  1 
ATOM   3360  C CG  . PRO A 1 422 ? -14.049 33.750  19.656  1.00 36.78  ? 422 PRO A CG  1 
ATOM   3361  C CD  . PRO A 1 422 ? -13.960 34.677  18.442  1.00 36.07  ? 422 PRO A CD  1 
ATOM   3362  N N   . LYS A 1 423 ? -18.083 33.545  20.109  1.00 33.35  ? 423 LYS A N   1 
ATOM   3363  C CA  . LYS A 1 423 ? -19.094 33.964  21.050  1.00 34.58  ? 423 LYS A CA  1 
ATOM   3364  C C   . LYS A 1 423 ? -18.678 33.436  22.414  1.00 31.47  ? 423 LYS A C   1 
ATOM   3365  O O   . LYS A 1 423 ? -18.395 32.248  22.548  1.00 30.96  ? 423 LYS A O   1 
ATOM   3366  C CB  . LYS A 1 423 ? -20.425 33.399  20.528  1.00 40.58  ? 423 LYS A CB  1 
ATOM   3367  C CG  . LYS A 1 423 ? -21.616 33.473  21.488  1.00 43.58  ? 423 LYS A CG  1 
ATOM   3368  C CD  . LYS A 1 423 ? -22.307 34.833  21.604  1.00 46.15  ? 423 LYS A CD  1 
ATOM   3369  C CE  . LYS A 1 423 ? -23.182 34.891  22.832  1.00 49.12  ? 423 LYS A CE  1 
ATOM   3370  N NZ  . LYS A 1 423 ? -23.675 36.250  23.051  1.00 51.77  ? 423 LYS A NZ  1 
ATOM   3371  N N   . SER A 1 424 ? -18.634 34.329  23.408  1.00 34.12  ? 424 SER A N   1 
ATOM   3372  C CA  . SER A 1 424 ? -18.418 33.943  24.800  1.00 32.65  ? 424 SER A CA  1 
ATOM   3373  C C   . SER A 1 424 ? -19.751 33.657  25.499  1.00 33.49  ? 424 SER A C   1 
ATOM   3374  O O   . SER A 1 424 ? -20.786 34.250  25.198  1.00 38.41  ? 424 SER A O   1 
ATOM   3375  C CB  . SER A 1 424 ? -17.652 34.999  25.549  1.00 31.53  ? 424 SER A CB  1 
ATOM   3376  O OG  . SER A 1 424 ? -18.518 36.067  25.905  1.00 31.60  ? 424 SER A OG  1 
ATOM   3377  N N   . ILE A 1 425 ? -19.698 32.741  26.462  1.00 32.10  ? 425 ILE A N   1 
ATOM   3378  C CA  . ILE A 1 425 ? -20.870 32.336  27.202  1.00 31.97  ? 425 ILE A CA  1 
ATOM   3379  C C   . ILE A 1 425 ? -20.597 32.599  28.672  1.00 34.04  ? 425 ILE A C   1 
ATOM   3380  O O   . ILE A 1 425 ? -19.446 32.619  29.084  1.00 35.68  ? 425 ILE A O   1 
ATOM   3381  C CB  . ILE A 1 425 ? -21.206 30.859  26.937  1.00 31.58  ? 425 ILE A CB  1 
ATOM   3382  C CG1 . ILE A 1 425 ? -20.166 29.916  27.552  1.00 31.45  ? 425 ILE A CG1 1 
ATOM   3383  C CG2 . ILE A 1 425 ? -21.404 30.608  25.438  1.00 31.48  ? 425 ILE A CG2 1 
ATOM   3384  C CD1 . ILE A 1 425 ? -20.460 28.437  27.335  1.00 31.69  ? 425 ILE A CD1 1 
ATOM   3385  N N   . THR A 1 426 ? -21.675 32.774  29.438  1.00 33.65  ? 426 THR A N   1 
ATOM   3386  C CA  . THR A 1 426 ? -21.607 32.958  30.870  1.00 32.01  ? 426 THR A CA  1 
ATOM   3387  C C   . THR A 1 426 ? -21.870 31.615  31.525  1.00 36.92  ? 426 THR A C   1 
ATOM   3388  O O   . THR A 1 426 ? -22.504 30.756  30.908  1.00 33.61  ? 426 THR A O   1 
ATOM   3389  C CB  . THR A 1 426 ? -22.648 33.975  31.306  1.00 32.65  ? 426 THR A CB  1 
ATOM   3390  O OG1 . THR A 1 426 ? -23.931 33.412  31.059  1.00 33.14  ? 426 THR A OG1 1 
ATOM   3391  C CG2 . THR A 1 426 ? -22.536 35.243  30.489  1.00 36.06  ? 426 THR A CG2 1 
ATOM   3392  N N   . THR A 1 427 ? -21.315 31.470  32.738  1.00 38.19  ? 427 THR A N   1 
ATOM   3393  C CA  . THR A 1 427 ? -21.609 30.378  33.644  1.00 37.80  ? 427 THR A CA  1 
ATOM   3394  C C   . THR A 1 427 ? -23.108 30.445  33.956  1.00 38.86  ? 427 THR A C   1 
ATOM   3395  O O   . THR A 1 427 ? -23.789 29.423  33.954  1.00 38.65  ? 427 THR A O   1 
ATOM   3396  C CB  . THR A 1 427 ? -20.716 30.512  34.891  1.00 39.96  ? 427 THR A CB  1 
ATOM   3397  O OG1 . THR A 1 427 ? -19.323 30.473  34.562  1.00 37.04  ? 427 THR A OG1 1 
ATOM   3398  C CG2 . THR A 1 427 ? -20.963 29.424  35.922  1.00 40.12  ? 427 THR A CG2 1 
ATOM   3399  N N   . ARG A 1 428 ? -23.641 31.656  34.179  1.00 34.51  ? 428 ARG A N   1 
ATOM   3400  C CA  . ARG A 1 428 ? -25.060 31.794  34.459  1.00 33.89  ? 428 ARG A CA  1 
ATOM   3401  C C   . ARG A 1 428 ? -25.838 30.969  33.437  1.00 36.18  ? 428 ARG A C   1 
ATOM   3402  O O   . ARG A 1 428 ? -26.653 30.137  33.814  1.00 38.96  ? 428 ARG A O   1 
ATOM   3403  C CB  . ARG A 1 428 ? -25.512 33.263  34.432  1.00 36.84  ? 428 ARG A CB  1 
ATOM   3404  C CG  . ARG A 1 428 ? -26.987 33.548  34.706  1.00 37.11  ? 428 ARG A CG  1 
ATOM   3405  C CD  . ARG A 1 428 ? -27.512 34.869  34.113  1.00 37.14  ? 428 ARG A CD  1 
ATOM   3406  N NE  . ARG A 1 428 ? -27.594 34.845  32.646  1.00 38.12  ? 428 ARG A NE  1 
ATOM   3407  C CZ  . ARG A 1 428 ? -28.346 34.038  31.878  1.00 40.99  ? 428 ARG A CZ  1 
ATOM   3408  N NH1 . ARG A 1 428 ? -29.265 33.244  32.400  1.00 46.63  ? 428 ARG A NH1 1 
ATOM   3409  N NH2 . ARG A 1 428 ? -28.184 34.021  30.567  1.00 38.50  ? 428 ARG A NH2 1 
ATOM   3410  N N   . TRP A 1 429 ? -25.558 31.205  32.146  1.00 38.26  ? 429 TRP A N   1 
ATOM   3411  C CA  . TRP A 1 429 ? -26.293 30.613  31.040  1.00 36.53  ? 429 TRP A CA  1 
ATOM   3412  C C   . TRP A 1 429 ? -26.162 29.096  31.090  1.00 41.62  ? 429 TRP A C   1 
ATOM   3413  O O   . TRP A 1 429 ? -27.148 28.378  30.938  1.00 46.98  ? 429 TRP A O   1 
ATOM   3414  C CB  . TRP A 1 429 ? -25.777 31.168  29.709  1.00 33.25  ? 429 TRP A CB  1 
ATOM   3415  C CG  . TRP A 1 429 ? -26.403 30.527  28.498  1.00 34.88  ? 429 TRP A CG  1 
ATOM   3416  C CD1 . TRP A 1 429 ? -27.609 30.852  27.953  1.00 37.92  ? 429 TRP A CD1 1 
ATOM   3417  C CD2 . TRP A 1 429 ? -25.857 29.497  27.647  1.00 31.86  ? 429 TRP A CD2 1 
ATOM   3418  N NE1 . TRP A 1 429 ? -27.864 30.088  26.852  1.00 35.08  ? 429 TRP A NE1 1 
ATOM   3419  C CE2 . TRP A 1 429 ? -26.810 29.252  26.633  1.00 34.92  ? 429 TRP A CE2 1 
ATOM   3420  C CE3 . TRP A 1 429 ? -24.667 28.775  27.634  1.00 31.39  ? 429 TRP A CE3 1 
ATOM   3421  C CZ2 . TRP A 1 429 ? -26.619 28.308  25.625  1.00 38.95  ? 429 TRP A CZ2 1 
ATOM   3422  C CZ3 . TRP A 1 429 ? -24.473 27.849  26.636  1.00 37.36  ? 429 TRP A CZ3 1 
ATOM   3423  C CH2 . TRP A 1 429 ? -25.430 27.616  25.641  1.00 39.35  ? 429 TRP A CH2 1 
ATOM   3424  N N   . VAL A 1 430 ? -24.932 28.628  31.318  1.00 41.36  ? 430 VAL A N   1 
ATOM   3425  C CA  . VAL A 1 430 ? -24.635 27.211  31.419  1.00 42.34  ? 430 VAL A CA  1 
ATOM   3426  C C   . VAL A 1 430 ? -25.461 26.533  32.517  1.00 41.11  ? 430 VAL A C   1 
ATOM   3427  O O   . VAL A 1 430 ? -26.088 25.511  32.259  1.00 43.23  ? 430 VAL A O   1 
ATOM   3428  C CB  . VAL A 1 430 ? -23.132 27.008  31.668  1.00 42.93  ? 430 VAL A CB  1 
ATOM   3429  C CG1 . VAL A 1 430 ? -22.848 25.569  32.069  1.00 41.36  ? 430 VAL A CG1 1 
ATOM   3430  C CG2 . VAL A 1 430 ? -22.316 27.407  30.445  1.00 45.36  ? 430 VAL A CG2 1 
ATOM   3431  N N   . LYS A 1 431 ? -25.420 27.061  33.745  1.00 40.55  ? 431 LYS A N   1 
ATOM   3432  C CA  . LYS A 1 431 ? -26.256 26.562  34.828  1.00 45.86  ? 431 LYS A CA  1 
ATOM   3433  C C   . LYS A 1 431 ? -27.730 26.491  34.414  1.00 52.91  ? 431 LYS A C   1 
ATOM   3434  O O   . LYS A 1 431 ? -28.411 25.539  34.783  1.00 50.38  ? 431 LYS A O   1 
ATOM   3435  C CB  . LYS A 1 431 ? -26.233 27.488  36.043  1.00 47.35  ? 431 LYS A CB  1 
ATOM   3436  C CG  . LYS A 1 431 ? -24.975 27.494  36.872  1.00 54.73  ? 431 LYS A CG  1 
ATOM   3437  C CD  . LYS A 1 431 ? -25.233 28.334  38.117  1.00 59.47  ? 431 LYS A CD  1 
ATOM   3438  C CE  . LYS A 1 431 ? -24.024 28.541  38.948  1.00 65.62  ? 431 LYS A CE  1 
ATOM   3439  N NZ  . LYS A 1 431 ? -24.301 29.485  40.032  1.00 70.18  ? 431 LYS A NZ  1 
ATOM   3440  N N   . GLU A 1 432 ? -28.218 27.524  33.696  1.00 53.50  ? 432 GLU A N   1 
ATOM   3441  C CA  . GLU A 1 432 ? -29.605 27.613  33.269  1.00 51.19  ? 432 GLU A CA  1 
ATOM   3442  C C   . GLU A 1 432 ? -29.944 26.475  32.303  1.00 56.69  ? 432 GLU A C   1 
ATOM   3443  O O   . GLU A 1 432 ? -30.908 25.754  32.551  1.00 68.86  ? 432 GLU A O   1 
ATOM   3444  C CB  . GLU A 1 432 ? -29.914 28.956  32.614  1.00 54.44  ? 432 GLU A CB  1 
ATOM   3445  C CG  . GLU A 1 432 ? -31.385 29.147  32.251  1.00 57.49  ? 432 GLU A CG  1 
ATOM   3446  C CD  . GLU A 1 432 ? -31.599 30.324  31.320  1.00 61.93  ? 432 GLU A CD  1 
ATOM   3447  O OE1 . GLU A 1 432 ? -32.201 30.124  30.253  1.00 65.74  ? 432 GLU A OE1 1 
ATOM   3448  O OE2 . GLU A 1 432 ? -31.141 31.436  31.637  1.00 64.64  ? 432 GLU A OE2 1 
ATOM   3449  N N   . VAL A 1 433 ? -29.151 26.290  31.233  1.00 46.69  ? 433 VAL A N   1 
ATOM   3450  C CA  . VAL A 1 433 ? -29.568 25.461  30.107  1.00 45.54  ? 433 VAL A CA  1 
ATOM   3451  C C   . VAL A 1 433 ? -28.931 24.074  30.144  1.00 44.08  ? 433 VAL A C   1 
ATOM   3452  O O   . VAL A 1 433 ? -29.312 23.227  29.349  1.00 50.16  ? 433 VAL A O   1 
ATOM   3453  C CB  . VAL A 1 433 ? -29.264 26.074  28.719  1.00 49.25  ? 433 VAL A CB  1 
ATOM   3454  C CG1 . VAL A 1 433 ? -29.800 27.499  28.541  1.00 47.92  ? 433 VAL A CG1 1 
ATOM   3455  C CG2 . VAL A 1 433 ? -27.782 25.988  28.373  1.00 48.24  ? 433 VAL A CG2 1 
ATOM   3456  N N   . ALA A 1 434 ? -27.916 23.864  30.984  1.00 43.76  ? 434 ALA A N   1 
ATOM   3457  C CA  . ALA A 1 434 ? -27.042 22.710  30.852  1.00 44.28  ? 434 ALA A CA  1 
ATOM   3458  C C   . ALA A 1 434 ? -27.825 21.400  30.793  1.00 46.89  ? 434 ALA A C   1 
ATOM   3459  O O   . ALA A 1 434 ? -27.478 20.515  30.012  1.00 44.99  ? 434 ALA A O   1 
ATOM   3460  C CB  . ALA A 1 434 ? -26.053 22.687  31.991  1.00 45.77  ? 434 ALA A CB  1 
ATOM   3461  N N   . GLU A 1 435 ? -28.852 21.285  31.652  1.00 58.66  ? 435 GLU A N   1 
ATOM   3462  C CA  . GLU A 1 435 ? -29.626 20.064  31.817  1.00 58.64  ? 435 GLU A CA  1 
ATOM   3463  C C   . GLU A 1 435 ? -30.367 19.749  30.521  1.00 54.63  ? 435 GLU A C   1 
ATOM   3464  O O   . GLU A 1 435 ? -30.444 18.590  30.132  1.00 51.74  ? 435 GLU A O   1 
ATOM   3465  C CB  . GLU A 1 435 ? -30.604 20.178  32.988  1.00 66.90  ? 435 GLU A CB  1 
ATOM   3466  C CG  . GLU A 1 435 ? -29.931 20.226  34.357  1.00 81.36  ? 435 GLU A CG  1 
ATOM   3467  C CD  . GLU A 1 435 ? -29.428 18.892  34.898  1.00 92.72  ? 435 GLU A CD  1 
ATOM   3468  O OE1 . GLU A 1 435 ? -28.432 18.329  34.390  1.00 81.24  ? 435 GLU A OE1 1 
ATOM   3469  O OE2 . GLU A 1 435 ? -30.056 18.405  35.865  1.00 112.03 ? 435 GLU A OE2 1 
ATOM   3470  N N   . SER A 1 436 ? -30.877 20.793  29.858  1.00 52.58  ? 436 SER A N   1 
ATOM   3471  C CA  . SER A 1 436 ? -31.732 20.659  28.689  1.00 58.23  ? 436 SER A CA  1 
ATOM   3472  C C   . SER A 1 436 ? -30.929 20.368  27.418  1.00 58.81  ? 436 SER A C   1 
ATOM   3473  O O   . SER A 1 436 ? -31.490 19.994  26.386  1.00 51.59  ? 436 SER A O   1 
ATOM   3474  C CB  . SER A 1 436 ? -32.574 21.898  28.530  1.00 63.54  ? 436 SER A CB  1 
ATOM   3475  O OG  . SER A 1 436 ? -31.754 23.055  28.421  1.00 72.07  ? 436 SER A OG  1 
ATOM   3476  N N   . LEU A 1 437 ? -29.605 20.540  27.489  1.00 62.04  ? 437 LEU A N   1 
ATOM   3477  C CA  . LEU A 1 437 ? -28.743 20.305  26.341  1.00 59.72  ? 437 LEU A CA  1 
ATOM   3478  C C   . LEU A 1 437 ? -28.565 18.807  26.130  1.00 52.13  ? 437 LEU A C   1 
ATOM   3479  O O   . LEU A 1 437 ? -28.441 18.056  27.092  1.00 46.93  ? 437 LEU A O   1 
ATOM   3480  C CB  . LEU A 1 437 ? -27.377 20.973  26.530  1.00 56.21  ? 437 LEU A CB  1 
ATOM   3481  C CG  . LEU A 1 437 ? -27.366 22.502  26.568  1.00 53.26  ? 437 LEU A CG  1 
ATOM   3482  C CD1 . LEU A 1 437 ? -25.934 22.960  26.708  1.00 54.78  ? 437 LEU A CD1 1 
ATOM   3483  C CD2 . LEU A 1 437 ? -28.017 23.148  25.347  1.00 51.40  ? 437 LEU A CD2 1 
ATOM   3484  N N   . PRO A 1 438 ? -28.467 18.351  24.864  1.00 50.73  ? 438 PRO A N   1 
ATOM   3485  C CA  . PRO A 1 438 ? -28.073 16.972  24.578  1.00 50.76  ? 438 PRO A CA  1 
ATOM   3486  C C   . PRO A 1 438 ? -26.601 16.716  24.909  1.00 55.25  ? 438 PRO A C   1 
ATOM   3487  O O   . PRO A 1 438 ? -25.853 17.661  25.120  1.00 52.45  ? 438 PRO A O   1 
ATOM   3488  C CB  . PRO A 1 438 ? -28.371 16.815  23.072  1.00 49.49  ? 438 PRO A CB  1 
ATOM   3489  C CG  . PRO A 1 438 ? -28.331 18.228  22.520  1.00 50.12  ? 438 PRO A CG  1 
ATOM   3490  C CD  . PRO A 1 438 ? -28.746 19.145  23.655  1.00 49.03  ? 438 PRO A CD  1 
ATOM   3491  N N   . VAL A 1 439 ? -26.208 15.434  24.926  1.00 53.69  ? 439 VAL A N   1 
ATOM   3492  C CA  . VAL A 1 439 ? -24.838 15.010  25.154  1.00 56.44  ? 439 VAL A CA  1 
ATOM   3493  C C   . VAL A 1 439 ? -24.238 14.576  23.822  1.00 59.84  ? 439 VAL A C   1 
ATOM   3494  O O   . VAL A 1 439 ? -24.849 13.798  23.096  1.00 60.58  ? 439 VAL A O   1 
ATOM   3495  C CB  . VAL A 1 439 ? -24.831 13.863  26.185  1.00 57.73  ? 439 VAL A CB  1 
ATOM   3496  C CG1 . VAL A 1 439 ? -23.527 13.075  26.203  1.00 56.26  ? 439 VAL A CG1 1 
ATOM   3497  C CG2 . VAL A 1 439 ? -25.161 14.379  27.579  1.00 62.67  ? 439 VAL A CG2 1 
ATOM   3498  N N   . ALA A 1 440 ? -23.025 15.050  23.516  1.00 65.32  ? 440 ALA A N   1 
ATOM   3499  C CA  . ALA A 1 440 ? -22.399 14.738  22.237  1.00 69.26  ? 440 ALA A CA  1 
ATOM   3500  C C   . ALA A 1 440 ? -22.419 13.224  22.000  1.00 61.61  ? 440 ALA A C   1 
ATOM   3501  O O   . ALA A 1 440 ? -21.505 12.636  22.594  1.00 56.22  ? 440 ALA A O   1 
ATOM   3502  C CB  . ALA A 1 440 ? -20.985 15.290  22.177  1.00 63.42  ? 440 ALA A CB  1 
ATOM   3503  N N   . MET B 1 1   ? -8.520  46.068  51.956  1.00 46.89  ? 1   MET B N   1 
ATOM   3504  C CA  . MET B 1 1   ? -9.345  46.450  50.782  1.00 46.06  ? 1   MET B CA  1 
ATOM   3505  C C   . MET B 1 1   ? -10.505 45.459  50.625  1.00 45.16  ? 1   MET B C   1 
ATOM   3506  O O   . MET B 1 1   ? -10.294 44.267  50.388  1.00 40.78  ? 1   MET B O   1 
ATOM   3507  C CB  . MET B 1 1   ? -8.465  46.512  49.529  1.00 44.53  ? 1   MET B CB  1 
ATOM   3508  C CG  . MET B 1 1   ? -9.082  47.300  48.385  1.00 44.68  ? 1   MET B CG  1 
ATOM   3509  S SD  . MET B 1 1   ? -8.549  46.736  46.752  1.00 44.41  ? 1   MET B SD  1 
ATOM   3510  C CE  . MET B 1 1   ? -8.764  48.369  46.032  1.00 51.39  ? 1   MET B CE  1 
ATOM   3511  N N   . LYS B 1 2   ? -11.741 45.967  50.761  1.00 50.16  ? 2   LYS B N   1 
ATOM   3512  C CA  . LYS B 1 2   ? -12.935 45.129  50.754  1.00 53.28  ? 2   LYS B CA  1 
ATOM   3513  C C   . LYS B 1 2   ? -12.943 44.235  49.518  1.00 47.79  ? 2   LYS B C   1 
ATOM   3514  O O   . LYS B 1 2   ? -13.200 43.033  49.624  1.00 40.33  ? 2   LYS B O   1 
ATOM   3515  C CB  . LYS B 1 2   ? -14.241 45.935  50.759  1.00 64.74  ? 2   LYS B CB  1 
ATOM   3516  C CG  . LYS B 1 2   ? -14.462 46.780  52.006  1.00 79.43  ? 2   LYS B CG  1 
ATOM   3517  C CD  . LYS B 1 2   ? -14.674 45.958  53.272  1.00 84.54  ? 2   LYS B CD  1 
ATOM   3518  C CE  . LYS B 1 2   ? -14.690 46.806  54.503  1.00 81.26  ? 2   LYS B CE  1 
ATOM   3519  N NZ  . LYS B 1 2   ? -14.884 45.961  55.683  1.00 76.58  ? 2   LYS B NZ  1 
ATOM   3520  N N   . LEU B 1 3   ? -12.655 44.844  48.359  1.00 44.33  ? 3   LEU B N   1 
ATOM   3521  C CA  . LEU B 1 3   ? -12.685 44.144  47.089  1.00 44.58  ? 3   LEU B CA  1 
ATOM   3522  C C   . LEU B 1 3   ? -11.866 42.854  47.181  1.00 41.95  ? 3   LEU B C   1 
ATOM   3523  O O   . LEU B 1 3   ? -12.351 41.795  46.803  1.00 42.88  ? 3   LEU B O   1 
ATOM   3524  C CB  . LEU B 1 3   ? -12.206 45.102  45.997  1.00 42.78  ? 3   LEU B CB  1 
ATOM   3525  C CG  . LEU B 1 3   ? -12.091 44.522  44.581  1.00 41.74  ? 3   LEU B CG  1 
ATOM   3526  C CD1 . LEU B 1 3   ? -13.403 43.976  44.052  1.00 40.81  ? 3   LEU B CD1 1 
ATOM   3527  C CD2 . LEU B 1 3   ? -11.530 45.585  43.636  1.00 41.18  ? 3   LEU B CD2 1 
ATOM   3528  N N   . LYS B 1 4   ? -10.650 42.929  47.737  1.00 43.82  ? 4   LYS B N   1 
ATOM   3529  C CA  . LYS B 1 4   ? -9.762  41.772  47.805  1.00 44.15  ? 4   LYS B CA  1 
ATOM   3530  C C   . LYS B 1 4   ? -10.311 40.754  48.801  1.00 44.28  ? 4   LYS B C   1 
ATOM   3531  O O   . LYS B 1 4   ? -10.228 39.549  48.542  1.00 42.55  ? 4   LYS B O   1 
ATOM   3532  C CB  . LYS B 1 4   ? -8.318  42.131  48.190  1.00 42.67  ? 4   LYS B CB  1 
ATOM   3533  C CG  . LYS B 1 4   ? -7.366  40.940  48.370  1.00 42.93  ? 4   LYS B CG  1 
ATOM   3534  C CD  . LYS B 1 4   ? -5.954  41.387  48.741  1.00 47.32  ? 4   LYS B CD  1 
ATOM   3535  C CE  . LYS B 1 4   ? -5.017  40.326  49.269  1.00 51.54  ? 4   LYS B CE  1 
ATOM   3536  N NZ  . LYS B 1 4   ? -4.156  39.692  48.270  1.00 44.94  ? 4   LYS B NZ  1 
ATOM   3537  N N   . GLU B 1 5   ? -10.820 41.254  49.942  1.00 37.45  ? 5   GLU B N   1 
ATOM   3538  C CA  . GLU B 1 5   ? -11.424 40.394  50.945  1.00 42.17  ? 5   GLU B CA  1 
ATOM   3539  C C   . GLU B 1 5   ? -12.563 39.584  50.322  1.00 41.43  ? 5   GLU B C   1 
ATOM   3540  O O   . GLU B 1 5   ? -12.612 38.358  50.418  1.00 40.04  ? 5   GLU B O   1 
ATOM   3541  C CB  . GLU B 1 5   ? -11.874 41.215  52.154  1.00 44.82  ? 5   GLU B CB  1 
ATOM   3542  C CG  . GLU B 1 5   ? -10.767 41.519  53.167  1.00 45.74  ? 5   GLU B CG  1 
ATOM   3543  C CD  . GLU B 1 5   ? -11.180 42.621  54.131  1.00 53.27  ? 5   GLU B CD  1 
ATOM   3544  O OE1 . GLU B 1 5   ? -10.284 43.104  54.832  1.00 63.84  ? 5   GLU B OE1 1 
ATOM   3545  O OE2 . GLU B 1 5   ? -12.369 43.021  54.196  1.00 57.83  ? 5   GLU B OE2 1 
ATOM   3546  N N   . ARG B 1 6   ? -13.438 40.288  49.611  1.00 41.64  ? 6   ARG B N   1 
ATOM   3547  C CA  . ARG B 1 6   ? -14.616 39.698  49.006  1.00 40.69  ? 6   ARG B CA  1 
ATOM   3548  C C   . ARG B 1 6   ? -14.235 38.706  47.913  1.00 40.62  ? 6   ARG B C   1 
ATOM   3549  O O   . ARG B 1 6   ? -14.862 37.652  47.778  1.00 39.92  ? 6   ARG B O   1 
ATOM   3550  C CB  . ARG B 1 6   ? -15.419 40.901  48.506  1.00 46.83  ? 6   ARG B CB  1 
ATOM   3551  C CG  . ARG B 1 6   ? -16.902 40.642  48.375  1.00 47.51  ? 6   ARG B CG  1 
ATOM   3552  C CD  . ARG B 1 6   ? -17.544 40.467  49.725  1.00 48.42  ? 6   ARG B CD  1 
ATOM   3553  N NE  . ARG B 1 6   ? -18.659 39.580  49.392  1.00 50.82  ? 6   ARG B NE  1 
ATOM   3554  C CZ  . ARG B 1 6   ? -18.734 38.282  49.610  1.00 48.94  ? 6   ARG B CZ  1 
ATOM   3555  N NH1 . ARG B 1 6   ? -17.811 37.665  50.314  1.00 54.19  ? 6   ARG B NH1 1 
ATOM   3556  N NH2 . ARG B 1 6   ? -19.761 37.600  49.144  1.00 47.84  ? 6   ARG B NH2 1 
ATOM   3557  N N   . LEU B 1 7   ? -13.200 39.044  47.133  1.00 38.52  ? 7   LEU B N   1 
ATOM   3558  C CA  . LEU B 1 7   ? -12.698 38.123  46.123  1.00 37.14  ? 7   LEU B CA  1 
ATOM   3559  C C   . LEU B 1 7   ? -12.098 36.884  46.800  1.00 34.09  ? 7   LEU B C   1 
ATOM   3560  O O   . LEU B 1 7   ? -12.235 35.780  46.269  1.00 30.33  ? 7   LEU B O   1 
ATOM   3561  C CB  . LEU B 1 7   ? -11.688 38.791  45.185  1.00 36.40  ? 7   LEU B CB  1 
ATOM   3562  C CG  . LEU B 1 7   ? -12.215 39.815  44.174  1.00 34.60  ? 7   LEU B CG  1 
ATOM   3563  C CD1 . LEU B 1 7   ? -11.062 40.500  43.413  1.00 31.95  ? 7   LEU B CD1 1 
ATOM   3564  C CD2 . LEU B 1 7   ? -13.169 39.153  43.198  1.00 37.18  ? 7   LEU B CD2 1 
ATOM   3565  N N   . ALA B 1 8   ? -11.458 37.061  47.971  1.00 36.30  ? 8   ALA B N   1 
ATOM   3566  C CA  . ALA B 1 8   ? -10.799 35.970  48.702  1.00 39.33  ? 8   ALA B CA  1 
ATOM   3567  C C   . ALA B 1 8   ? -11.776 34.859  49.109  1.00 38.78  ? 8   ALA B C   1 
ATOM   3568  O O   . ALA B 1 8   ? -11.366 33.695  49.155  1.00 35.04  ? 8   ALA B O   1 
ATOM   3569  C CB  . ALA B 1 8   ? -10.057 36.506  49.914  1.00 35.20  ? 8   ALA B CB  1 
ATOM   3570  N N   . GLU B 1 9   ? -13.041 35.257  49.384  1.00 40.98  ? 9   GLU B N   1 
ATOM   3571  C CA  . GLU B 1 9   ? -14.179 34.388  49.696  1.00 45.28  ? 9   GLU B CA  1 
ATOM   3572  C C   . GLU B 1 9   ? -14.801 33.748  48.447  1.00 39.44  ? 9   GLU B C   1 
ATOM   3573  O O   . GLU B 1 9   ? -15.085 32.541  48.460  1.00 37.54  ? 9   GLU B O   1 
ATOM   3574  C CB  . GLU B 1 9   ? -15.255 35.189  50.446  1.00 50.94  ? 9   GLU B CB  1 
ATOM   3575  C CG  . GLU B 1 9   ? -15.074 35.208  51.971  1.00 62.30  ? 9   GLU B CG  1 
ATOM   3576  C CD  . GLU B 1 9   ? -15.813 36.263  52.809  1.00 67.35  ? 9   GLU B CD  1 
ATOM   3577  O OE1 . GLU B 1 9   ? -15.783 36.178  54.061  1.00 59.51  ? 9   GLU B OE1 1 
ATOM   3578  O OE2 . GLU B 1 9   ? -16.404 37.204  52.239  1.00 70.98  ? 9   GLU B OE2 1 
ATOM   3579  N N   . LEU B 1 10  ? -14.983 34.565  47.387  1.00 31.41  ? 10  LEU B N   1 
ATOM   3580  C CA  . LEU B 1 10  ? -15.787 34.232  46.218  1.00 31.98  ? 10  LEU B CA  1 
ATOM   3581  C C   . LEU B 1 10  ? -15.032 33.364  45.223  1.00 31.77  ? 10  LEU B C   1 
ATOM   3582  O O   . LEU B 1 10  ? -15.630 32.485  44.605  1.00 33.67  ? 10  LEU B O   1 
ATOM   3583  C CB  . LEU B 1 10  ? -16.235 35.515  45.508  1.00 37.27  ? 10  LEU B CB  1 
ATOM   3584  C CG  . LEU B 1 10  ? -17.379 36.317  46.146  1.00 41.84  ? 10  LEU B CG  1 
ATOM   3585  C CD1 . LEU B 1 10  ? -17.546 37.741  45.623  1.00 39.54  ? 10  LEU B CD1 1 
ATOM   3586  C CD2 . LEU B 1 10  ? -18.677 35.547  45.930  1.00 46.10  ? 10  LEU B CD2 1 
ATOM   3587  N N   . ILE B 1 11  ? -13.747 33.683  44.997  1.00 31.92  ? 11  ILE B N   1 
ATOM   3588  C CA  . ILE B 1 11  ? -12.974 33.032  43.956  1.00 31.17  ? 11  ILE B CA  1 
ATOM   3589  C C   . ILE B 1 11  ? -12.852 31.540  44.272  1.00 31.68  ? 11  ILE B C   1 
ATOM   3590  O O   . ILE B 1 11  ? -13.249 30.726  43.446  1.00 39.66  ? 11  ILE B O   1 
ATOM   3591  C CB  . ILE B 1 11  ? -11.642 33.771  43.694  1.00 31.28  ? 11  ILE B CB  1 
ATOM   3592  C CG1 . ILE B 1 11  ? -11.908 35.022  42.859  1.00 31.90  ? 11  ILE B CG1 1 
ATOM   3593  C CG2 . ILE B 1 11  ? -10.616 32.880  42.996  1.00 31.67  ? 11  ILE B CG2 1 
ATOM   3594  C CD1 . ILE B 1 11  ? -10.771 36.012  42.820  1.00 30.81  ? 11  ILE B CD1 1 
ATOM   3595  N N   . PRO B 1 12  ? -12.420 31.111  45.474  1.00 30.83  ? 12  PRO B N   1 
ATOM   3596  C CA  . PRO B 1 12  ? -12.440 29.678  45.815  1.00 36.78  ? 12  PRO B CA  1 
ATOM   3597  C C   . PRO B 1 12  ? -13.731 28.898  45.543  1.00 39.70  ? 12  PRO B C   1 
ATOM   3598  O O   . PRO B 1 12  ? -13.674 27.749  45.091  1.00 39.34  ? 12  PRO B O   1 
ATOM   3599  C CB  . PRO B 1 12  ? -12.072 29.629  47.314  1.00 36.38  ? 12  PRO B CB  1 
ATOM   3600  C CG  . PRO B 1 12  ? -11.337 30.951  47.567  1.00 37.43  ? 12  PRO B CG  1 
ATOM   3601  C CD  . PRO B 1 12  ? -11.896 31.964  46.555  1.00 33.92  ? 12  PRO B CD  1 
ATOM   3602  N N   . GLN B 1 13  ? -14.900 29.510  45.800  1.00 40.53  ? 13  GLN B N   1 
ATOM   3603  C CA  . GLN B 1 13  ? -16.162 28.849  45.480  1.00 42.97  ? 13  GLN B CA  1 
ATOM   3604  C C   . GLN B 1 13  ? -16.383 28.777  43.964  1.00 43.76  ? 13  GLN B C   1 
ATOM   3605  O O   . GLN B 1 13  ? -16.882 27.767  43.454  1.00 41.87  ? 13  GLN B O   1 
ATOM   3606  C CB  . GLN B 1 13  ? -17.400 29.535  46.049  1.00 48.72  ? 13  GLN B CB  1 
ATOM   3607  C CG  . GLN B 1 13  ? -17.333 29.887  47.532  1.00 53.59  ? 13  GLN B CG  1 
ATOM   3608  C CD  . GLN B 1 13  ? -18.520 30.740  47.931  1.00 58.69  ? 13  GLN B CD  1 
ATOM   3609  O OE1 . GLN B 1 13  ? -19.574 30.700  47.282  1.00 65.63  ? 13  GLN B OE1 1 
ATOM   3610  N NE2 . GLN B 1 13  ? -18.362 31.534  48.980  1.00 53.50  ? 13  GLN B NE2 1 
ATOM   3611  N N   . TRP B 1 14  ? -16.044 29.861  43.240  1.00 37.38  ? 14  TRP B N   1 
ATOM   3612  C CA  . TRP B 1 14  ? -16.258 29.898  41.803  1.00 33.00  ? 14  TRP B CA  1 
ATOM   3613  C C   . TRP B 1 14  ? -15.391 28.844  41.139  1.00 31.85  ? 14  TRP B C   1 
ATOM   3614  O O   . TRP B 1 14  ? -15.825 28.100  40.264  1.00 29.74  ? 14  TRP B O   1 
ATOM   3615  C CB  . TRP B 1 14  ? -15.943 31.297  41.259  1.00 35.44  ? 14  TRP B CB  1 
ATOM   3616  C CG  . TRP B 1 14  ? -16.983 32.348  41.551  1.00 31.88  ? 14  TRP B CG  1 
ATOM   3617  C CD1 . TRP B 1 14  ? -18.306 32.145  41.797  1.00 31.17  ? 14  TRP B CD1 1 
ATOM   3618  C CD2 . TRP B 1 14  ? -16.777 33.776  41.608  1.00 30.42  ? 14  TRP B CD2 1 
ATOM   3619  N NE1 . TRP B 1 14  ? -18.936 33.340  42.008  1.00 33.37  ? 14  TRP B NE1 1 
ATOM   3620  C CE2 . TRP B 1 14  ? -18.031 34.359  41.884  1.00 31.17  ? 14  TRP B CE2 1 
ATOM   3621  C CE3 . TRP B 1 14  ? -15.667 34.614  41.458  1.00 30.10  ? 14  TRP B CE3 1 
ATOM   3622  C CZ2 . TRP B 1 14  ? -18.201 35.731  42.021  1.00 29.61  ? 14  TRP B CZ2 1 
ATOM   3623  C CZ3 . TRP B 1 14  ? -15.833 35.977  41.581  1.00 28.51  ? 14  TRP B CZ3 1 
ATOM   3624  C CH2 . TRP B 1 14  ? -17.089 36.524  41.855  1.00 31.20  ? 14  TRP B CH2 1 
ATOM   3625  N N   . ARG B 1 15  ? -14.147 28.785  41.599  1.00 36.93  ? 15  ARG B N   1 
ATOM   3626  C CA  . ARG B 1 15  ? -13.204 27.794  41.121  1.00 42.28  ? 15  ARG B CA  1 
ATOM   3627  C C   . ARG B 1 15  ? -13.813 26.402  41.251  1.00 40.86  ? 15  ARG B C   1 
ATOM   3628  O O   . ARG B 1 15  ? -13.732 25.610  40.312  1.00 37.12  ? 15  ARG B O   1 
ATOM   3629  C CB  . ARG B 1 15  ? -11.903 27.938  41.915  1.00 49.46  ? 15  ARG B CB  1 
ATOM   3630  C CG  . ARG B 1 15  ? -10.957 26.757  41.773  1.00 59.64  ? 15  ARG B CG  1 
ATOM   3631  C CD  . ARG B 1 15  ? -9.645  27.062  42.451  1.00 70.63  ? 15  ARG B CD  1 
ATOM   3632  N NE  . ARG B 1 15  ? -8.932  25.823  42.782  1.00 82.58  ? 15  ARG B NE  1 
ATOM   3633  C CZ  . ARG B 1 15  ? -8.407  25.539  43.976  1.00 89.51  ? 15  ARG B CZ  1 
ATOM   3634  N NH1 . ARG B 1 15  ? -8.393  26.446  44.946  1.00 86.06  ? 15  ARG B NH1 1 
ATOM   3635  N NH2 . ARG B 1 15  ? -7.885  24.342  44.185  1.00 89.03  ? 15  ARG B NH2 1 
ATOM   3636  N N   . ALA B 1 16  ? -14.386 26.116  42.432  1.00 43.73  ? 16  ALA B N   1 
ATOM   3637  C CA  . ALA B 1 16  ? -15.006 24.824  42.711  1.00 45.34  ? 16  ALA B CA  1 
ATOM   3638  C C   . ALA B 1 16  ? -16.210 24.609  41.798  1.00 47.28  ? 16  ALA B C   1 
ATOM   3639  O O   . ALA B 1 16  ? -16.377 23.514  41.255  1.00 39.86  ? 16  ALA B O   1 
ATOM   3640  C CB  . ALA B 1 16  ? -15.418 24.728  44.154  1.00 42.56  ? 16  ALA B CB  1 
ATOM   3641  N N   . GLU B 1 17  ? -17.015 25.672  41.628  1.00 49.80  ? 17  GLU B N   1 
ATOM   3642  C CA  . GLU B 1 17  ? -18.188 25.618  40.768  1.00 57.41  ? 17  GLU B CA  1 
ATOM   3643  C C   . GLU B 1 17  ? -17.746 25.258  39.356  1.00 49.09  ? 17  GLU B C   1 
ATOM   3644  O O   . GLU B 1 17  ? -18.306 24.351  38.740  1.00 51.09  ? 17  GLU B O   1 
ATOM   3645  C CB  . GLU B 1 17  ? -19.057 26.883  40.772  1.00 69.98  ? 17  GLU B CB  1 
ATOM   3646  C CG  . GLU B 1 17  ? -20.439 26.700  41.401  1.00 89.74  ? 17  GLU B CG  1 
ATOM   3647  C CD  . GLU B 1 17  ? -21.362 25.716  40.666  1.00 115.29 ? 17  GLU B CD  1 
ATOM   3648  O OE1 . GLU B 1 17  ? -21.192 24.469  40.731  1.00 112.66 ? 17  GLU B OE1 1 
ATOM   3649  O OE2 . GLU B 1 17  ? -22.289 26.212  39.992  1.00 127.50 ? 17  GLU B OE2 1 
ATOM   3650  N N   . VAL B 1 18  ? -16.720 25.950  38.858  1.00 45.19  ? 18  VAL B N   1 
ATOM   3651  C CA  . VAL B 1 18  ? -16.293 25.741  37.481  1.00 41.65  ? 18  VAL B CA  1 
ATOM   3652  C C   . VAL B 1 18  ? -15.771 24.312  37.306  1.00 42.89  ? 18  VAL B C   1 
ATOM   3653  O O   . VAL B 1 18  ? -16.086 23.656  36.310  1.00 43.55  ? 18  VAL B O   1 
ATOM   3654  C CB  . VAL B 1 18  ? -15.281 26.826  37.067  1.00 39.18  ? 18  VAL B CB  1 
ATOM   3655  C CG1 . VAL B 1 18  ? -14.561 26.512  35.768  1.00 37.35  ? 18  VAL B CG1 1 
ATOM   3656  C CG2 . VAL B 1 18  ? -15.972 28.181  36.972  1.00 39.08  ? 18  VAL B CG2 1 
ATOM   3657  N N   . ALA B 1 19  ? -15.004 23.817  38.291  1.00 45.59  ? 19  ALA B N   1 
ATOM   3658  C CA  . ALA B 1 19  ? -14.494 22.451  38.244  1.00 46.42  ? 19  ALA B CA  1 
ATOM   3659  C C   . ALA B 1 19  ? -15.644 21.470  38.063  1.00 39.07  ? 19  ALA B C   1 
ATOM   3660  O O   . ALA B 1 19  ? -15.541 20.553  37.267  1.00 34.78  ? 19  ALA B O   1 
ATOM   3661  C CB  . ALA B 1 19  ? -13.702 22.130  39.493  1.00 47.14  ? 19  ALA B CB  1 
ATOM   3662  N N   . GLU B 1 20  ? -16.723 21.706  38.816  1.00 45.50  ? 20  GLU B N   1 
ATOM   3663  C CA  . GLU B 1 20  ? -17.930 20.890  38.824  1.00 47.24  ? 20  GLU B CA  1 
ATOM   3664  C C   . GLU B 1 20  ? -18.587 20.883  37.453  1.00 44.39  ? 20  GLU B C   1 
ATOM   3665  O O   . GLU B 1 20  ? -19.025 19.829  36.986  1.00 46.79  ? 20  GLU B O   1 
ATOM   3666  C CB  . GLU B 1 20  ? -18.945 21.380  39.863  1.00 54.27  ? 20  GLU B CB  1 
ATOM   3667  C CG  . GLU B 1 20  ? -19.119 20.418  41.035  1.00 65.74  ? 20  GLU B CG  1 
ATOM   3668  C CD  . GLU B 1 20  ? -19.801 19.128  40.602  1.00 75.79  ? 20  GLU B CD  1 
ATOM   3669  O OE1 . GLU B 1 20  ? -20.983 19.246  40.214  1.00 78.44  ? 20  GLU B OE1 1 
ATOM   3670  O OE2 . GLU B 1 20  ? -19.175 18.035  40.613  1.00 83.05  ? 20  GLU B OE2 1 
ATOM   3671  N N   . ILE B 1 21  ? -18.690 22.068  36.842  1.00 42.97  ? 21  ILE B N   1 
ATOM   3672  C CA  . ILE B 1 21  ? -19.398 22.210  35.576  1.00 43.82  ? 21  ILE B CA  1 
ATOM   3673  C C   . ILE B 1 21  ? -18.647 21.424  34.511  1.00 42.05  ? 21  ILE B C   1 
ATOM   3674  O O   . ILE B 1 21  ? -19.243 20.704  33.717  1.00 42.56  ? 21  ILE B O   1 
ATOM   3675  C CB  . ILE B 1 21  ? -19.607 23.699  35.220  1.00 45.29  ? 21  ILE B CB  1 
ATOM   3676  C CG1 . ILE B 1 21  ? -20.656 24.342  36.154  1.00 48.26  ? 21  ILE B CG1 1 
ATOM   3677  C CG2 . ILE B 1 21  ? -19.976 23.879  33.748  1.00 45.29  ? 21  ILE B CG2 1 
ATOM   3678  C CD1 . ILE B 1 21  ? -20.762 25.850  36.064  1.00 49.18  ? 21  ILE B CD1 1 
ATOM   3679  N N   . ARG B 1 22  ? -17.318 21.518  34.549  1.00 42.98  ? 22  ARG B N   1 
ATOM   3680  C CA  . ARG B 1 22  ? -16.501 20.848  33.558  1.00 42.63  ? 22  ARG B CA  1 
ATOM   3681  C C   . ARG B 1 22  ? -16.640 19.338  33.674  1.00 41.64  ? 22  ARG B C   1 
ATOM   3682  O O   . ARG B 1 22  ? -16.705 18.646  32.664  1.00 45.15  ? 22  ARG B O   1 
ATOM   3683  C CB  . ARG B 1 22  ? -15.053 21.297  33.728  1.00 46.11  ? 22  ARG B CB  1 
ATOM   3684  C CG  . ARG B 1 22  ? -14.899 22.769  33.365  1.00 50.77  ? 22  ARG B CG  1 
ATOM   3685  C CD  . ARG B 1 22  ? -13.455 23.205  33.529  1.00 49.72  ? 22  ARG B CD  1 
ATOM   3686  N NE  . ARG B 1 22  ? -12.590 22.553  32.545  1.00 42.28  ? 22  ARG B NE  1 
ATOM   3687  C CZ  . ARG B 1 22  ? -11.273 22.577  32.608  1.00 46.10  ? 22  ARG B CZ  1 
ATOM   3688  N NH1 . ARG B 1 22  ? -10.668 23.088  33.668  1.00 43.46  ? 22  ARG B NH1 1 
ATOM   3689  N NH2 . ARG B 1 22  ? -10.571 22.070  31.610  1.00 47.34  ? 22  ARG B NH2 1 
ATOM   3690  N N   . LYS B 1 23  ? -16.659 18.844  34.910  1.00 44.12  ? 23  LYS B N   1 
ATOM   3691  C CA  . LYS B 1 23  ? -16.739 17.418  35.187  1.00 50.48  ? 23  LYS B CA  1 
ATOM   3692  C C   . LYS B 1 23  ? -18.136 16.900  34.828  1.00 57.00  ? 23  LYS B C   1 
ATOM   3693  O O   . LYS B 1 23  ? -18.259 15.889  34.133  1.00 49.16  ? 23  LYS B O   1 
ATOM   3694  C CB  . LYS B 1 23  ? -16.310 17.205  36.647  1.00 55.31  ? 23  LYS B CB  1 
ATOM   3695  C CG  . LYS B 1 23  ? -16.372 15.775  37.144  1.00 66.11  ? 23  LYS B CG  1 
ATOM   3696  C CD  . LYS B 1 23  ? -15.326 15.396  38.193  1.00 79.53  ? 23  LYS B CD  1 
ATOM   3697  C CE  . LYS B 1 23  ? -15.434 13.921  38.535  1.00 95.92  ? 23  LYS B CE  1 
ATOM   3698  N NZ  . LYS B 1 23  ? -14.207 13.191  38.882  1.00 93.46  ? 23  LYS B NZ  1 
ATOM   3699  N N   . LYS B 1 24  ? -19.175 17.624  35.279  1.00 59.97  ? 24  LYS B N   1 
ATOM   3700  C CA  . LYS B 1 24  ? -20.558 17.192  35.158  1.00 59.65  ? 24  LYS B CA  1 
ATOM   3701  C C   . LYS B 1 24  ? -21.082 17.483  33.749  1.00 60.86  ? 24  LYS B C   1 
ATOM   3702  O O   . LYS B 1 24  ? -21.641 16.594  33.122  1.00 65.40  ? 24  LYS B O   1 
ATOM   3703  C CB  . LYS B 1 24  ? -21.358 17.847  36.292  1.00 66.41  ? 24  LYS B CB  1 
ATOM   3704  C CG  . LYS B 1 24  ? -22.800 17.372  36.418  1.00 79.61  ? 24  LYS B CG  1 
ATOM   3705  C CD  . LYS B 1 24  ? -23.464 17.470  37.794  1.00 88.05  ? 24  LYS B CD  1 
ATOM   3706  C CE  . LYS B 1 24  ? -23.959 18.830  38.214  1.00 94.09  ? 24  LYS B CE  1 
ATOM   3707  N NZ  . LYS B 1 24  ? -24.835 18.780  39.392  1.00 90.72  ? 24  LYS B NZ  1 
ATOM   3708  N N   . TYR B 1 25  ? -20.841 18.693  33.220  1.00 59.25  ? 25  TYR B N   1 
ATOM   3709  C CA  . TYR B 1 25  ? -21.535 19.181  32.035  1.00 53.86  ? 25  TYR B CA  1 
ATOM   3710  C C   . TYR B 1 25  ? -20.624 19.391  30.828  1.00 55.47  ? 25  TYR B C   1 
ATOM   3711  O O   . TYR B 1 25  ? -21.053 19.997  29.845  1.00 55.97  ? 25  TYR B O   1 
ATOM   3712  C CB  . TYR B 1 25  ? -22.162 20.529  32.377  1.00 51.93  ? 25  TYR B CB  1 
ATOM   3713  C CG  . TYR B 1 25  ? -23.322 20.434  33.352  1.00 55.34  ? 25  TYR B CG  1 
ATOM   3714  C CD1 . TYR B 1 25  ? -24.327 19.495  33.172  1.00 59.30  ? 25  TYR B CD1 1 
ATOM   3715  C CD2 . TYR B 1 25  ? -23.405 21.270  34.464  1.00 60.33  ? 25  TYR B CD2 1 
ATOM   3716  C CE1 . TYR B 1 25  ? -25.390 19.406  34.055  1.00 61.07  ? 25  TYR B CE1 1 
ATOM   3717  C CE2 . TYR B 1 25  ? -24.459 21.183  35.362  1.00 60.16  ? 25  TYR B CE2 1 
ATOM   3718  C CZ  . TYR B 1 25  ? -25.456 20.252  35.146  1.00 58.02  ? 25  TYR B CZ  1 
ATOM   3719  O OH  . TYR B 1 25  ? -26.521 20.147  35.976  1.00 67.18  ? 25  TYR B OH  1 
ATOM   3720  N N   . GLY B 1 26  ? -19.396 18.862  30.887  1.00 54.02  ? 26  GLY B N   1 
ATOM   3721  C CA  . GLY B 1 26  ? -18.392 19.077  29.854  1.00 50.88  ? 26  GLY B CA  1 
ATOM   3722  C C   . GLY B 1 26  ? -18.777 18.511  28.488  1.00 49.40  ? 26  GLY B C   1 
ATOM   3723  O O   . GLY B 1 26  ? -18.488 19.128  27.459  1.00 55.04  ? 26  GLY B O   1 
ATOM   3724  N N   . ASN B 1 27  ? -19.441 17.350  28.473  1.00 49.05  ? 27  ASN B N   1 
ATOM   3725  C CA  . ASN B 1 27  ? -19.767 16.682  27.219  1.00 52.69  ? 27  ASN B CA  1 
ATOM   3726  C C   . ASN B 1 27  ? -21.101 17.184  26.642  1.00 47.92  ? 27  ASN B C   1 
ATOM   3727  O O   . ASN B 1 27  ? -21.576 16.625  25.654  1.00 45.44  ? 27  ASN B O   1 
ATOM   3728  C CB  . ASN B 1 27  ? -19.703 15.160  27.359  1.00 57.45  ? 27  ASN B CB  1 
ATOM   3729  C CG  . ASN B 1 27  ? -20.401 14.659  28.602  1.00 62.93  ? 27  ASN B CG  1 
ATOM   3730  O OD1 . ASN B 1 27  ? -19.774 13.999  29.432  1.00 76.37  ? 27  ASN B OD1 1 
ATOM   3731  N ND2 . ASN B 1 27  ? -21.671 14.989  28.783  1.00 61.69  ? 27  ASN B ND2 1 
ATOM   3732  N N   . ARG B 1 28  ? -21.710 18.224  27.246  1.00 47.54  ? 28  ARG B N   1 
ATOM   3733  C CA  . ARG B 1 28  ? -22.967 18.781  26.767  1.00 44.08  ? 28  ARG B CA  1 
ATOM   3734  C C   . ARG B 1 28  ? -22.694 19.634  25.531  1.00 45.83  ? 28  ARG B C   1 
ATOM   3735  O O   . ARG B 1 28  ? -21.855 20.523  25.576  1.00 52.62  ? 28  ARG B O   1 
ATOM   3736  C CB  . ARG B 1 28  ? -23.674 19.680  27.790  1.00 50.01  ? 28  ARG B CB  1 
ATOM   3737  C CG  . ARG B 1 28  ? -24.235 19.055  29.063  1.00 54.64  ? 28  ARG B CG  1 
ATOM   3738  C CD  . ARG B 1 28  ? -25.207 17.913  28.831  1.00 58.73  ? 28  ARG B CD  1 
ATOM   3739  N NE  . ARG B 1 28  ? -25.653 17.386  30.126  1.00 64.50  ? 28  ARG B NE  1 
ATOM   3740  C CZ  . ARG B 1 28  ? -26.899 17.047  30.464  1.00 62.29  ? 28  ARG B CZ  1 
ATOM   3741  N NH1 . ARG B 1 28  ? -27.196 16.874  31.735  1.00 59.16  ? 28  ARG B NH1 1 
ATOM   3742  N NH2 . ARG B 1 28  ? -27.861 16.947  29.566  1.00 64.04  ? 28  ARG B NH2 1 
ATOM   3743  N N   . LYS B 1 29  ? -23.414 19.353  24.440  1.00 41.21  ? 29  LYS B N   1 
ATOM   3744  C CA  . LYS B 1 29  ? -23.261 20.053  23.177  1.00 39.31  ? 29  LYS B CA  1 
ATOM   3745  C C   . LYS B 1 29  ? -24.074 21.339  23.199  1.00 38.57  ? 29  LYS B C   1 
ATOM   3746  O O   . LYS B 1 29  ? -25.215 21.321  23.639  1.00 41.19  ? 29  LYS B O   1 
ATOM   3747  C CB  . LYS B 1 29  ? -23.715 19.136  22.034  1.00 40.69  ? 29  LYS B CB  1 
ATOM   3748  C CG  . LYS B 1 29  ? -24.210 19.852  20.802  1.00 42.87  ? 29  LYS B CG  1 
ATOM   3749  C CD  . LYS B 1 29  ? -24.438 18.977  19.578  1.00 46.77  ? 29  LYS B CD  1 
ATOM   3750  C CE  . LYS B 1 29  ? -25.337 19.659  18.565  1.00 50.14  ? 29  LYS B CE  1 
ATOM   3751  N NZ  . LYS B 1 29  ? -25.166 19.081  17.229  1.00 48.66  ? 29  LYS B NZ  1 
ATOM   3752  N N   . THR B 1 30  ? -23.478 22.432  22.696  1.00 39.12  ? 30  THR B N   1 
ATOM   3753  C CA  . THR B 1 30  ? -24.129 23.732  22.572  1.00 38.16  ? 30  THR B CA  1 
ATOM   3754  C C   . THR B 1 30  ? -24.520 23.982  21.115  1.00 39.33  ? 30  THR B C   1 
ATOM   3755  O O   . THR B 1 30  ? -25.497 24.681  20.869  1.00 40.44  ? 30  THR B O   1 
ATOM   3756  C CB  . THR B 1 30  ? -23.237 24.868  23.091  1.00 39.00  ? 30  THR B CB  1 
ATOM   3757  O OG1 . THR B 1 30  ? -22.033 24.987  22.334  1.00 40.01  ? 30  THR B OG1 1 
ATOM   3758  C CG2 . THR B 1 30  ? -22.831 24.663  24.537  1.00 41.20  ? 30  THR B CG2 1 
ATOM   3759  N N   . MET B 1 31  ? -23.744 23.462  20.151  1.00 38.45  ? 31  MET B N   1 
ATOM   3760  C CA  . MET B 1 31  ? -23.986 23.741  18.737  1.00 41.92  ? 31  MET B CA  1 
ATOM   3761  C C   . MET B 1 31  ? -23.115 22.835  17.869  1.00 38.59  ? 31  MET B C   1 
ATOM   3762  O O   . MET B 1 31  ? -22.282 22.101  18.386  1.00 37.47  ? 31  MET B O   1 
ATOM   3763  C CB  . MET B 1 31  ? -23.702 25.212  18.385  1.00 42.62  ? 31  MET B CB  1 
ATOM   3764  C CG  . MET B 1 31  ? -22.283 25.666  18.706  1.00 41.90  ? 31  MET B CG  1 
ATOM   3765  S SD  . MET B 1 31  ? -22.158 27.467  18.745  1.00 40.73  ? 31  MET B SD  1 
ATOM   3766  C CE  . MET B 1 31  ? -22.257 27.788  16.975  1.00 43.68  ? 31  MET B CE  1 
ATOM   3767  N N   . ASP B 1 32  ? -23.357 22.882  16.554  1.00 41.19  ? 32  ASP B N   1 
ATOM   3768  C CA  . ASP B 1 32  ? -22.477 22.286  15.557  1.00 47.17  ? 32  ASP B CA  1 
ATOM   3769  C C   . ASP B 1 32  ? -21.259 23.202  15.312  1.00 45.70  ? 32  ASP B C   1 
ATOM   3770  O O   . ASP B 1 32  ? -21.379 24.429  15.366  1.00 41.70  ? 32  ASP B O   1 
ATOM   3771  C CB  . ASP B 1 32  ? -23.228 21.976  14.259  1.00 46.80  ? 32  ASP B CB  1 
ATOM   3772  C CG  . ASP B 1 32  ? -24.250 20.841  14.272  1.00 49.35  ? 32  ASP B CG  1 
ATOM   3773  O OD1 . ASP B 1 32  ? -23.976 19.805  14.923  1.00 47.18  ? 32  ASP B OD1 1 
ATOM   3774  O OD2 . ASP B 1 32  ? -25.289 20.966  13.563  1.00 51.68  ? 32  ASP B OD2 1 
ATOM   3775  N N   . CYS B 1 33  ? -20.090 22.582  15.040  1.00 41.06  ? 33  CYS B N   1 
ATOM   3776  C CA  . CYS B 1 33  ? -18.915 23.255  14.504  1.00 41.56  ? 33  CYS B CA  1 
ATOM   3777  C C   . CYS B 1 33  ? -18.823 22.947  13.012  1.00 41.92  ? 33  CYS B C   1 
ATOM   3778  O O   . CYS B 1 33  ? -18.842 21.784  12.613  1.00 43.21  ? 33  CYS B O   1 
ATOM   3779  C CB  . CYS B 1 33  ? -17.626 22.772  15.173  1.00 45.71  ? 33  CYS B CB  1 
ATOM   3780  S SG  . CYS B 1 33  ? -16.182 23.854  14.928  1.00 39.77  ? 33  CYS B SG  1 
ATOM   3781  N N   . THR B 1 34  ? -18.668 23.984  12.188  1.00 40.35  ? 34  THR B N   1 
ATOM   3782  C CA  . THR B 1 34  ? -18.782 23.804  10.752  1.00 42.21  ? 34  THR B CA  1 
ATOM   3783  C C   . THR B 1 34  ? -17.508 24.295  10.076  1.00 40.47  ? 34  THR B C   1 
ATOM   3784  O O   . THR B 1 34  ? -16.738 25.045  10.658  1.00 44.98  ? 34  THR B O   1 
ATOM   3785  C CB  . THR B 1 34  ? -20.019 24.528  10.215  1.00 43.65  ? 34  THR B CB  1 
ATOM   3786  O OG1 . THR B 1 34  ? -19.804 25.939  10.166  1.00 42.15  ? 34  THR B OG1 1 
ATOM   3787  C CG2 . THR B 1 34  ? -21.262 24.223  11.031  1.00 41.05  ? 34  THR B CG2 1 
ATOM   3788  N N   . ILE B 1 35  ? -17.314 23.848  8.835   1.00 39.68  ? 35  ILE B N   1 
ATOM   3789  C CA  . ILE B 1 35  ? -16.275 24.358  7.963   1.00 37.85  ? 35  ILE B CA  1 
ATOM   3790  C C   . ILE B 1 35  ? -16.354 25.876  7.918   1.00 37.09  ? 35  ILE B C   1 
ATOM   3791  O O   . ILE B 1 35  ? -15.319 26.507  7.840   1.00 45.01  ? 35  ILE B O   1 
ATOM   3792  C CB  . ILE B 1 35  ? -16.414 23.779  6.545   1.00 40.29  ? 35  ILE B CB  1 
ATOM   3793  C CG1 . ILE B 1 35  ? -16.254 22.266  6.536   1.00 39.80  ? 35  ILE B CG1 1 
ATOM   3794  C CG2 . ILE B 1 35  ? -15.435 24.465  5.586   1.00 40.97  ? 35  ILE B CG2 1 
ATOM   3795  C CD1 . ILE B 1 35  ? -14.878 21.789  6.957   1.00 40.44  ? 35  ILE B CD1 1 
ATOM   3796  N N   . GLY B 1 36  ? -17.570 26.442  7.928   1.00 35.08  ? 36  GLY B N   1 
ATOM   3797  C CA  . GLY B 1 36  ? -17.774 27.878  7.804   1.00 34.86  ? 36  GLY B CA  1 
ATOM   3798  C C   . GLY B 1 36  ? -17.237 28.650  9.014   1.00 38.55  ? 36  GLY B C   1 
ATOM   3799  O O   . GLY B 1 36  ? -16.711 29.752  8.862   1.00 38.70  ? 36  GLY B O   1 
ATOM   3800  N N   . HIS B 1 37  ? -17.385 28.061  10.211  1.00 36.28  ? 37  HIS B N   1 
ATOM   3801  C CA  . HIS B 1 37  ? -16.776 28.567  11.432  1.00 37.97  ? 37  HIS B CA  1 
ATOM   3802  C C   . HIS B 1 37  ? -15.282 28.807  11.181  1.00 38.02  ? 37  HIS B C   1 
ATOM   3803  O O   . HIS B 1 37  ? -14.770 29.902  11.456  1.00 33.45  ? 37  HIS B O   1 
ATOM   3804  C CB  . HIS B 1 37  ? -17.087 27.632  12.627  1.00 36.72  ? 37  HIS B CB  1 
ATOM   3805  C CG  . HIS B 1 37  ? -18.490 27.745  13.150  1.00 34.38  ? 37  HIS B CG  1 
ATOM   3806  N ND1 . HIS B 1 37  ? -19.130 28.969  13.270  1.00 36.36  ? 37  HIS B ND1 1 
ATOM   3807  C CD2 . HIS B 1 37  ? -19.383 26.837  13.556  1.00 33.76  ? 37  HIS B CD2 1 
ATOM   3808  C CE1 . HIS B 1 37  ? -20.372 28.783  13.705  1.00 34.15  ? 37  HIS B CE1 1 
ATOM   3809  N NE2 . HIS B 1 37  ? -20.542 27.501  13.918  1.00 31.64  ? 37  HIS B NE2 1 
ATOM   3810  N N   . ALA B 1 38  ? -14.607 27.790  10.621  1.00 33.45  ? 38  ALA B N   1 
ATOM   3811  C CA  . ALA B 1 38  ? -13.156 27.826  10.513  1.00 37.29  ? 38  ALA B CA  1 
ATOM   3812  C C   . ALA B 1 38  ? -12.706 28.934  9.559   1.00 39.29  ? 38  ALA B C   1 
ATOM   3813  O O   . ALA B 1 38  ? -11.742 29.649  9.840   1.00 34.38  ? 38  ALA B O   1 
ATOM   3814  C CB  . ALA B 1 38  ? -12.630 26.474  10.105  1.00 36.87  ? 38  ALA B CB  1 
ATOM   3815  N N   . TYR B 1 39  ? -13.423 29.091  8.437   1.00 40.51  ? 39  TYR B N   1 
ATOM   3816  C CA  . TYR B 1 39  ? -13.084 30.092  7.435   1.00 36.31  ? 39  TYR B CA  1 
ATOM   3817  C C   . TYR B 1 39  ? -13.773 31.416  7.744   1.00 36.86  ? 39  TYR B C   1 
ATOM   3818  O O   . TYR B 1 39  ? -13.576 32.384  7.029   1.00 38.61  ? 39  TYR B O   1 
ATOM   3819  C CB  . TYR B 1 39  ? -13.501 29.567  6.055   1.00 35.51  ? 39  TYR B CB  1 
ATOM   3820  C CG  . TYR B 1 39  ? -12.580 28.499  5.490   1.00 37.01  ? 39  TYR B CG  1 
ATOM   3821  C CD1 . TYR B 1 39  ? -12.719 27.161  5.829   1.00 41.35  ? 39  TYR B CD1 1 
ATOM   3822  C CD2 . TYR B 1 39  ? -11.547 28.842  4.636   1.00 36.15  ? 39  TYR B CD2 1 
ATOM   3823  C CE1 . TYR B 1 39  ? -11.877 26.191  5.310   1.00 41.70  ? 39  TYR B CE1 1 
ATOM   3824  C CE2 . TYR B 1 39  ? -10.695 27.888  4.117   1.00 38.50  ? 39  TYR B CE2 1 
ATOM   3825  C CZ  . TYR B 1 39  ? -10.853 26.558  4.456   1.00 40.86  ? 39  TYR B CZ  1 
ATOM   3826  O OH  . TYR B 1 39  ? -9.984  25.637  3.931   1.00 43.30  ? 39  TYR B OH  1 
ATOM   3827  N N   . GLY B 1 40  ? -14.609 31.463  8.785   1.00 41.94  ? 40  GLY B N   1 
ATOM   3828  C CA  . GLY B 1 40  ? -15.512 32.589  8.975   1.00 41.95  ? 40  GLY B CA  1 
ATOM   3829  C C   . GLY B 1 40  ? -15.282 33.274  10.316  1.00 39.99  ? 40  GLY B C   1 
ATOM   3830  O O   . GLY B 1 40  ? -16.165 33.972  10.820  1.00 35.78  ? 40  GLY B O   1 
ATOM   3831  N N   . GLY B 1 41  ? -14.086 33.056  10.873  1.00 39.24  ? 41  GLY B N   1 
ATOM   3832  C CA  . GLY B 1 41  ? -13.655 33.746  12.078  1.00 38.82  ? 41  GLY B CA  1 
ATOM   3833  C C   . GLY B 1 41  ? -14.440 33.310  13.316  1.00 38.85  ? 41  GLY B C   1 
ATOM   3834  O O   . GLY B 1 41  ? -14.686 34.120  14.223  1.00 32.30  ? 41  GLY B O   1 
ATOM   3835  N N   . MET B 1 42  ? -14.820 32.026  13.363  1.00 36.94  ? 42  MET B N   1 
ATOM   3836  C CA  . MET B 1 42  ? -15.544 31.487  14.512  1.00 38.91  ? 42  MET B CA  1 
ATOM   3837  C C   . MET B 1 42  ? -16.875 32.205  14.776  1.00 34.56  ? 42  MET B C   1 
ATOM   3838  O O   . MET B 1 42  ? -17.401 32.065  15.872  1.00 38.00  ? 42  MET B O   1 
ATOM   3839  C CB  . MET B 1 42  ? -14.737 31.627  15.812  1.00 36.57  ? 42  MET B CB  1 
ATOM   3840  C CG  . MET B 1 42  ? -13.333 31.116  15.724  1.00 38.17  ? 42  MET B CG  1 
ATOM   3841  S SD  . MET B 1 42  ? -12.666 30.834  17.374  1.00 41.52  ? 42  MET B SD  1 
ATOM   3842  C CE  . MET B 1 42  ? -10.984 30.338  16.971  1.00 45.02  ? 42  MET B CE  1 
ATOM   3843  N N   . ARG B 1 43  ? -17.432 32.957  13.810  1.00 36.20  ? 43  ARG B N   1 
ATOM   3844  C CA  . ARG B 1 43  ? -18.637 33.742  14.051  1.00 40.48  ? 43  ARG B CA  1 
ATOM   3845  C C   . ARG B 1 43  ? -19.700 32.867  14.699  1.00 37.51  ? 43  ARG B C   1 
ATOM   3846  O O   . ARG B 1 43  ? -20.138 31.890  14.092  1.00 33.99  ? 43  ARG B O   1 
ATOM   3847  C CB  . ARG B 1 43  ? -19.258 34.318  12.778  1.00 49.65  ? 43  ARG B CB  1 
ATOM   3848  C CG  . ARG B 1 43  ? -20.283 35.412  13.051  1.00 63.08  ? 43  ARG B CG  1 
ATOM   3849  C CD  . ARG B 1 43  ? -21.214 35.619  11.844  1.00 83.52  ? 43  ARG B CD  1 
ATOM   3850  N NE  . ARG B 1 43  ? -22.145 36.752  11.982  1.00 97.04  ? 43  ARG B NE  1 
ATOM   3851  C CZ  . ARG B 1 43  ? -22.329 37.746  11.104  1.00 97.82  ? 43  ARG B CZ  1 
ATOM   3852  N NH1 . ARG B 1 43  ? -21.688 37.748  9.944   1.00 96.34  ? 43  ARG B NH1 1 
ATOM   3853  N NH2 . ARG B 1 43  ? -23.162 38.738  11.387  1.00 87.69  ? 43  ARG B NH2 1 
ATOM   3854  N N   . GLY B 1 44  ? -20.059 33.205  15.949  1.00 38.83  ? 44  GLY B N   1 
ATOM   3855  C CA  . GLY B 1 44  ? -21.123 32.523  16.673  1.00 42.45  ? 44  GLY B CA  1 
ATOM   3856  C C   . GLY B 1 44  ? -20.677 31.255  17.420  1.00 45.31  ? 44  GLY B C   1 
ATOM   3857  O O   . GLY B 1 44  ? -21.468 30.668  18.158  1.00 45.10  ? 44  GLY B O   1 
ATOM   3858  N N   . LEU B 1 45  ? -19.420 30.820  17.270  1.00 42.20  ? 45  LEU B N   1 
ATOM   3859  C CA  . LEU B 1 45  ? -18.982 29.594  17.919  1.00 40.47  ? 45  LEU B CA  1 
ATOM   3860  C C   . LEU B 1 45  ? -18.813 29.856  19.411  1.00 40.66  ? 45  LEU B C   1 
ATOM   3861  O O   . LEU B 1 45  ? -18.242 30.862  19.811  1.00 41.27  ? 45  LEU B O   1 
ATOM   3862  C CB  . LEU B 1 45  ? -17.682 29.106  17.292  1.00 40.11  ? 45  LEU B CB  1 
ATOM   3863  C CG  . LEU B 1 45  ? -17.308 27.650  17.569  1.00 43.36  ? 45  LEU B CG  1 
ATOM   3864  C CD1 . LEU B 1 45  ? -18.442 26.681  17.267  1.00 44.93  ? 45  LEU B CD1 1 
ATOM   3865  C CD2 . LEU B 1 45  ? -16.097 27.288  16.730  1.00 48.53  ? 45  LEU B CD2 1 
ATOM   3866  N N   . LYS B 1 46  ? -19.309 28.942  20.241  1.00 44.37  ? 46  LYS B N   1 
ATOM   3867  C CA  . LYS B 1 46  ? -19.320 29.146  21.684  1.00 42.30  ? 46  LYS B CA  1 
ATOM   3868  C C   . LYS B 1 46  ? -18.091 28.485  22.288  1.00 39.13  ? 46  LYS B C   1 
ATOM   3869  O O   . LYS B 1 46  ? -18.183 27.347  22.726  1.00 41.58  ? 46  LYS B O   1 
ATOM   3870  C CB  . LYS B 1 46  ? -20.621 28.581  22.268  1.00 42.92  ? 46  LYS B CB  1 
ATOM   3871  C CG  . LYS B 1 46  ? -21.845 29.390  21.853  1.00 44.66  ? 46  LYS B CG  1 
ATOM   3872  C CD  . LYS B 1 46  ? -23.189 28.866  22.330  1.00 44.80  ? 46  LYS B CD  1 
ATOM   3873  C CE  . LYS B 1 46  ? -24.322 29.626  21.710  1.00 43.70  ? 46  LYS B CE  1 
ATOM   3874  N NZ  . LYS B 1 46  ? -25.556 29.248  22.399  1.00 46.00  ? 46  LYS B NZ  1 
ATOM   3875  N N   . ALA B 1 47  ? -16.965 29.216  22.305  1.00 42.17  ? 47  ALA B N   1 
ATOM   3876  C CA  . ALA B 1 47  ? -15.640 28.649  22.553  1.00 44.35  ? 47  ALA B CA  1 
ATOM   3877  C C   . ALA B 1 47  ? -14.857 29.430  23.614  1.00 41.30  ? 47  ALA B C   1 
ATOM   3878  O O   . ALA B 1 47  ? -13.671 29.176  23.804  1.00 39.60  ? 47  ALA B O   1 
ATOM   3879  C CB  . ALA B 1 47  ? -14.872 28.613  21.241  1.00 45.78  ? 47  ALA B CB  1 
ATOM   3880  N N   . LEU B 1 48  ? -15.531 30.368  24.294  1.00 38.67  ? 48  LEU B N   1 
ATOM   3881  C CA  . LEU B 1 48  ? -14.950 31.207  25.330  1.00 38.49  ? 48  LEU B CA  1 
ATOM   3882  C C   . LEU B 1 48  ? -15.917 31.341  26.509  1.00 35.02  ? 48  LEU B C   1 
ATOM   3883  O O   . LEU B 1 48  ? -17.133 31.404  26.312  1.00 33.85  ? 48  LEU B O   1 
ATOM   3884  C CB  . LEU B 1 48  ? -14.719 32.599  24.741  1.00 40.97  ? 48  LEU B CB  1 
ATOM   3885  C CG  . LEU B 1 48  ? -13.457 32.821  23.920  1.00 43.49  ? 48  LEU B CG  1 
ATOM   3886  C CD1 . LEU B 1 48  ? -13.399 34.296  23.592  1.00 45.30  ? 48  LEU B CD1 1 
ATOM   3887  C CD2 . LEU B 1 48  ? -12.211 32.365  24.650  1.00 45.90  ? 48  LEU B CD2 1 
ATOM   3888  N N   . VAL B 1 49  ? -15.375 31.507  27.719  1.00 30.92  ? 49  VAL B N   1 
ATOM   3889  C CA  . VAL B 1 49  ? -16.189 31.856  28.868  1.00 32.56  ? 49  VAL B CA  1 
ATOM   3890  C C   . VAL B 1 49  ? -15.938 33.323  29.222  1.00 33.20  ? 49  VAL B C   1 
ATOM   3891  O O   . VAL B 1 49  ? -14.796 33.762  29.245  1.00 40.44  ? 49  VAL B O   1 
ATOM   3892  C CB  . VAL B 1 49  ? -15.859 30.918  30.042  1.00 33.15  ? 49  VAL B CB  1 
ATOM   3893  C CG1 . VAL B 1 49  ? -16.442 31.414  31.356  1.00 32.09  ? 49  VAL B CG1 1 
ATOM   3894  C CG2 . VAL B 1 49  ? -16.318 29.494  29.786  1.00 33.78  ? 49  VAL B CG2 1 
ATOM   3895  N N   . CYS B 1 50  ? -17.006 34.078  29.500  1.00 33.56  ? 50  CYS B N   1 
ATOM   3896  C CA  . CYS B 1 50  ? -16.915 35.415  30.080  1.00 33.54  ? 50  CYS B CA  1 
ATOM   3897  C C   . CYS B 1 50  ? -18.122 35.657  30.986  1.00 31.06  ? 50  CYS B C   1 
ATOM   3898  O O   . CYS B 1 50  ? -19.257 35.543  30.516  1.00 33.13  ? 50  CYS B O   1 
ATOM   3899  C CB  . CYS B 1 50  ? -16.824 36.521  29.024  1.00 31.05  ? 50  CYS B CB  1 
ATOM   3900  S SG  . CYS B 1 50  ? -17.210 38.177  29.660  1.00 32.33  ? 50  CYS B SG  1 
ATOM   3901  N N   . ASP B 1 51  ? -17.845 36.051  32.241  1.00 29.87  ? 51  ASP B N   1 
ATOM   3902  C CA  . ASP B 1 51  ? -18.846 36.279  33.267  1.00 30.59  ? 51  ASP B CA  1 
ATOM   3903  C C   . ASP B 1 51  ? -18.941 37.742  33.692  1.00 32.80  ? 51  ASP B C   1 
ATOM   3904  O O   . ASP B 1 51  ? -19.803 38.093  34.488  1.00 35.35  ? 51  ASP B O   1 
ATOM   3905  C CB  . ASP B 1 51  ? -18.548 35.465  34.514  1.00 33.12  ? 51  ASP B CB  1 
ATOM   3906  C CG  . ASP B 1 51  ? -18.870 33.998  34.337  1.00 33.34  ? 51  ASP B CG  1 
ATOM   3907  O OD1 . ASP B 1 51  ? -19.826 33.729  33.567  1.00 34.36  ? 51  ASP B OD1 1 
ATOM   3908  O OD2 . ASP B 1 51  ? -18.163 33.174  34.948  1.00 31.31  ? 51  ASP B OD2 1 
ATOM   3909  N N   . THR B 1 52  ? -18.088 38.622  33.188  1.00 31.37  ? 52  THR B N   1 
ATOM   3910  C CA  . THR B 1 52  ? -18.258 40.023  33.528  1.00 29.91  ? 52  THR B CA  1 
ATOM   3911  C C   . THR B 1 52  ? -19.524 40.602  32.892  1.00 28.72  ? 52  THR B C   1 
ATOM   3912  O O   . THR B 1 52  ? -20.189 41.452  33.489  1.00 28.06  ? 52  THR B O   1 
ATOM   3913  C CB  . THR B 1 52  ? -17.001 40.780  33.109  1.00 29.95  ? 52  THR B CB  1 
ATOM   3914  O OG1 . THR B 1 52  ? -16.627 40.241  31.839  1.00 33.24  ? 52  THR B OG1 1 
ATOM   3915  C CG2 . THR B 1 52  ? -15.908 40.557  34.135  1.00 30.02  ? 52  THR B CG2 1 
ATOM   3916  N N   . SER B 1 53  ? -19.849 40.182  31.660  1.00 29.56  ? 53  SER B N   1 
ATOM   3917  C CA  . SER B 1 53  ? -20.966 40.789  30.962  1.00 28.71  ? 53  SER B CA  1 
ATOM   3918  C C   . SER B 1 53  ? -21.526 39.820  29.926  1.00 30.96  ? 53  SER B C   1 
ATOM   3919  O O   . SER B 1 53  ? -20.915 38.789  29.618  1.00 32.49  ? 53  SER B O   1 
ATOM   3920  C CB  . SER B 1 53  ? -20.570 42.103  30.368  1.00 27.76  ? 53  SER B CB  1 
ATOM   3921  O OG  . SER B 1 53  ? -19.573 41.913  29.383  1.00 26.13  ? 53  SER B OG  1 
ATOM   3922  N N   . GLU B 1 54  ? -22.738 40.147  29.464  1.00 33.36  ? 54  GLU B N   1 
ATOM   3923  C CA  . GLU B 1 54  ? -23.536 39.272  28.613  1.00 36.36  ? 54  GLU B CA  1 
ATOM   3924  C C   . GLU B 1 54  ? -24.477 40.129  27.770  1.00 34.97  ? 54  GLU B C   1 
ATOM   3925  O O   . GLU B 1 54  ? -25.112 41.047  28.299  1.00 29.47  ? 54  GLU B O   1 
ATOM   3926  C CB  . GLU B 1 54  ? -24.337 38.278  29.455  1.00 37.19  ? 54  GLU B CB  1 
ATOM   3927  C CG  . GLU B 1 54  ? -25.106 37.233  28.645  1.00 36.98  ? 54  GLU B CG  1 
ATOM   3928  C CD  . GLU B 1 54  ? -25.701 36.121  29.503  1.00 35.09  ? 54  GLU B CD  1 
ATOM   3929  O OE1 . GLU B 1 54  ? -26.215 35.173  28.898  1.00 41.28  ? 54  GLU B OE1 1 
ATOM   3930  O OE2 . GLU B 1 54  ? -25.685 36.173  30.748  1.00 34.41  ? 54  GLU B OE2 1 
ATOM   3931  N N   . VAL B 1 55  ? -24.508 39.845  26.459  1.00 32.36  ? 55  VAL B N   1 
ATOM   3932  C CA  . VAL B 1 55  ? -25.289 40.632  25.522  1.00 35.82  ? 55  VAL B CA  1 
ATOM   3933  C C   . VAL B 1 55  ? -26.581 39.868  25.233  1.00 34.19  ? 55  VAL B C   1 
ATOM   3934  O O   . VAL B 1 55  ? -26.543 38.742  24.773  1.00 32.95  ? 55  VAL B O   1 
ATOM   3935  C CB  . VAL B 1 55  ? -24.511 40.935  24.222  1.00 38.89  ? 55  VAL B CB  1 
ATOM   3936  C CG1 . VAL B 1 55  ? -25.259 41.883  23.302  1.00 41.79  ? 55  VAL B CG1 1 
ATOM   3937  C CG2 . VAL B 1 55  ? -23.139 41.530  24.464  1.00 40.45  ? 55  VAL B CG2 1 
ATOM   3938  N N   . PHE B 1 56  ? -27.732 40.463  25.541  1.00 37.36  ? 56  PHE B N   1 
ATOM   3939  C CA  . PHE B 1 56  ? -29.012 39.867  25.171  1.00 38.09  ? 56  PHE B CA  1 
ATOM   3940  C C   . PHE B 1 56  ? -29.494 40.480  23.856  1.00 37.13  ? 56  PHE B C   1 
ATOM   3941  O O   . PHE B 1 56  ? -29.728 41.689  23.775  1.00 35.33  ? 56  PHE B O   1 
ATOM   3942  C CB  . PHE B 1 56  ? -29.975 40.048  26.347  1.00 36.13  ? 56  PHE B CB  1 
ATOM   3943  C CG  . PHE B 1 56  ? -29.527 39.248  27.560  1.00 36.73  ? 56  PHE B CG  1 
ATOM   3944  C CD1 . PHE B 1 56  ? -28.599 39.774  28.457  1.00 37.08  ? 56  PHE B CD1 1 
ATOM   3945  C CD2 . PHE B 1 56  ? -30.013 37.961  27.789  1.00 35.03  ? 56  PHE B CD2 1 
ATOM   3946  C CE1 . PHE B 1 56  ? -28.196 39.041  29.571  1.00 35.54  ? 56  PHE B CE1 1 
ATOM   3947  C CE2 . PHE B 1 56  ? -29.595 37.230  28.892  1.00 35.49  ? 56  PHE B CE2 1 
ATOM   3948  C CZ  . PHE B 1 56  ? -28.686 37.765  29.775  1.00 35.54  ? 56  PHE B CZ  1 
ATOM   3949  N N   . PRO B 1 57  ? -29.659 39.676  22.778  1.00 37.95  ? 57  PRO B N   1 
ATOM   3950  C CA  . PRO B 1 57  ? -30.148 40.205  21.501  1.00 40.55  ? 57  PRO B CA  1 
ATOM   3951  C C   . PRO B 1 57  ? -31.414 41.061  21.608  1.00 41.38  ? 57  PRO B C   1 
ATOM   3952  O O   . PRO B 1 57  ? -31.635 41.924  20.740  1.00 37.31  ? 57  PRO B O   1 
ATOM   3953  C CB  . PRO B 1 57  ? -30.354 38.949  20.615  1.00 41.69  ? 57  PRO B CB  1 
ATOM   3954  C CG  . PRO B 1 57  ? -29.425 37.896  21.226  1.00 41.04  ? 57  PRO B CG  1 
ATOM   3955  C CD  . PRO B 1 57  ? -29.366 38.232  22.718  1.00 40.59  ? 57  PRO B CD  1 
ATOM   3956  N N   . ASP B 1 58  ? -32.203 40.866  22.687  1.00 36.20  ? 58  ASP B N   1 
ATOM   3957  C CA  . ASP B 1 58  ? -33.452 41.599  22.848  1.00 38.61  ? 58  ASP B CA  1 
ATOM   3958  C C   . ASP B 1 58  ? -33.345 42.760  23.850  1.00 37.66  ? 58  ASP B C   1 
ATOM   3959  O O   . ASP B 1 58  ? -34.290 43.535  23.989  1.00 37.51  ? 58  ASP B O   1 
ATOM   3960  C CB  . ASP B 1 58  ? -34.621 40.640  23.049  1.00 39.87  ? 58  ASP B CB  1 
ATOM   3961  C CG  . ASP B 1 58  ? -34.913 39.720  21.859  1.00 42.96  ? 58  ASP B CG  1 
ATOM   3962  O OD1 . ASP B 1 58  ? -34.885 40.194  20.696  1.00 39.92  ? 58  ASP B OD1 1 
ATOM   3963  O OD2 . ASP B 1 58  ? -35.194 38.526  22.080  1.00 50.43  ? 58  ASP B OD2 1 
ATOM   3964  N N   . GLU B 1 59  ? -32.198 42.948  24.505  1.00 36.42  ? 59  GLU B N   1 
ATOM   3965  C CA  . GLU B 1 59  ? -32.118 43.928  25.580  1.00 35.94  ? 59  GLU B CA  1 
ATOM   3966  C C   . GLU B 1 59  ? -30.855 44.777  25.512  1.00 37.28  ? 59  GLU B C   1 
ATOM   3967  O O   . GLU B 1 59  ? -30.859 45.939  25.925  1.00 35.32  ? 59  GLU B O   1 
ATOM   3968  C CB  . GLU B 1 59  ? -32.096 43.215  26.926  1.00 41.86  ? 59  GLU B CB  1 
ATOM   3969  C CG  . GLU B 1 59  ? -33.397 42.477  27.225  1.00 47.19  ? 59  GLU B CG  1 
ATOM   3970  C CD  . GLU B 1 59  ? -33.513 42.067  28.677  1.00 50.46  ? 59  GLU B CD  1 
ATOM   3971  O OE1 . GLU B 1 59  ? -33.534 42.973  29.569  1.00 54.94  ? 59  GLU B OE1 1 
ATOM   3972  O OE2 . GLU B 1 59  ? -33.558 40.828  28.874  1.00 44.56  ? 59  GLU B OE2 1 
ATOM   3973  N N   . GLY B 1 60  ? -29.769 44.176  25.016  1.00 37.38  ? 60  GLY B N   1 
ATOM   3974  C CA  . GLY B 1 60  ? -28.466 44.814  25.027  1.00 35.98  ? 60  GLY B CA  1 
ATOM   3975  C C   . GLY B 1 60  ? -27.566 44.145  26.051  1.00 33.67  ? 60  GLY B C   1 
ATOM   3976  O O   . GLY B 1 60  ? -27.869 43.074  26.561  1.00 30.99  ? 60  GLY B O   1 
ATOM   3977  N N   . VAL B 1 61  ? -26.460 44.806  26.360  1.00 34.99  ? 61  VAL B N   1 
ATOM   3978  C CA  . VAL B 1 61  ? -25.498 44.251  27.288  1.00 33.01  ? 61  VAL B CA  1 
ATOM   3979  C C   . VAL B 1 61  ? -25.974 44.522  28.718  1.00 30.57  ? 61  VAL B C   1 
ATOM   3980  O O   . VAL B 1 61  ? -26.505 45.570  29.012  1.00 30.77  ? 61  VAL B O   1 
ATOM   3981  C CB  . VAL B 1 61  ? -24.082 44.805  27.020  1.00 31.15  ? 61  VAL B CB  1 
ATOM   3982  C CG1 . VAL B 1 61  ? -23.977 46.310  27.241  1.00 30.08  ? 61  VAL B CG1 1 
ATOM   3983  C CG2 . VAL B 1 61  ? -23.053 44.093  27.887  1.00 31.00  ? 61  VAL B CG2 1 
ATOM   3984  N N   . LYS B 1 62  ? -25.748 43.560  29.610  1.00 32.85  ? 62  LYS B N   1 
ATOM   3985  C CA  . LYS B 1 62  ? -25.855 43.759  31.040  1.00 35.00  ? 62  LYS B CA  1 
ATOM   3986  C C   . LYS B 1 62  ? -24.501 43.473  31.695  1.00 35.09  ? 62  LYS B C   1 
ATOM   3987  O O   . LYS B 1 62  ? -23.742 42.625  31.216  1.00 32.61  ? 62  LYS B O   1 
ATOM   3988  C CB  . LYS B 1 62  ? -26.882 42.762  31.578  1.00 36.79  ? 62  LYS B CB  1 
ATOM   3989  C CG  . LYS B 1 62  ? -28.284 42.925  30.995  1.00 42.24  ? 62  LYS B CG  1 
ATOM   3990  C CD  . LYS B 1 62  ? -29.330 41.984  31.582  1.00 41.91  ? 62  LYS B CD  1 
ATOM   3991  C CE  . LYS B 1 62  ? -30.667 42.162  30.947  1.00 47.76  ? 62  LYS B CE  1 
ATOM   3992  N NZ  . LYS B 1 62  ? -31.603 41.175  31.481  1.00 50.92  ? 62  LYS B NZ  1 
ATOM   3993  N N   . PHE B 1 63  ? -24.236 44.181  32.809  1.00 34.84  ? 63  PHE B N   1 
ATOM   3994  C CA  . PHE B 1 63  ? -23.050 43.993  33.630  1.00 32.18  ? 63  PHE B CA  1 
ATOM   3995  C C   . PHE B 1 63  ? -23.415 43.209  34.881  1.00 30.41  ? 63  PHE B C   1 
ATOM   3996  O O   . PHE B 1 63  ? -24.013 43.747  35.804  1.00 30.86  ? 63  PHE B O   1 
ATOM   3997  C CB  . PHE B 1 63  ? -22.444 45.339  34.030  1.00 28.78  ? 63  PHE B CB  1 
ATOM   3998  C CG  . PHE B 1 63  ? -22.059 46.229  32.852  1.00 29.09  ? 63  PHE B CG  1 
ATOM   3999  C CD1 . PHE B 1 63  ? -21.480 45.701  31.707  1.00 25.75  ? 63  PHE B CD1 1 
ATOM   4000  C CD2 . PHE B 1 63  ? -22.266 47.605  32.899  1.00 29.06  ? 63  PHE B CD2 1 
ATOM   4001  C CE1 . PHE B 1 63  ? -21.138 46.515  30.658  1.00 26.26  ? 63  PHE B CE1 1 
ATOM   4002  C CE2 . PHE B 1 63  ? -21.890 48.415  31.846  1.00 29.74  ? 63  PHE B CE2 1 
ATOM   4003  C CZ  . PHE B 1 63  ? -21.331 47.867  30.727  1.00 28.45  ? 63  PHE B CZ  1 
ATOM   4004  N N   . ARG B 1 64  ? -23.016 41.942  34.908  1.00 30.58  ? 64  ARG B N   1 
ATOM   4005  C CA  . ARG B 1 64  ? -23.284 41.075  36.041  1.00 33.50  ? 64  ARG B CA  1 
ATOM   4006  C C   . ARG B 1 64  ? -24.787 40.982  36.308  1.00 35.65  ? 64  ARG B C   1 
ATOM   4007  O O   . ARG B 1 64  ? -25.205 40.982  37.456  1.00 37.15  ? 64  ARG B O   1 
ATOM   4008  C CB  . ARG B 1 64  ? -22.485 41.570  37.248  1.00 32.46  ? 64  ARG B CB  1 
ATOM   4009  C CG  . ARG B 1 64  ? -21.021 41.154  37.194  1.00 31.44  ? 64  ARG B CG  1 
ATOM   4010  C CD  . ARG B 1 64  ? -20.887 39.646  37.284  1.00 29.40  ? 64  ARG B CD  1 
ATOM   4011  N NE  . ARG B 1 64  ? -19.479 39.393  37.562  1.00 30.84  ? 64  ARG B NE  1 
ATOM   4012  C CZ  . ARG B 1 64  ? -18.941 38.249  37.947  1.00 31.63  ? 64  ARG B CZ  1 
ATOM   4013  N NH1 . ARG B 1 64  ? -19.666 37.168  38.002  1.00 27.56  ? 64  ARG B NH1 1 
ATOM   4014  N NH2 . ARG B 1 64  ? -17.653 38.181  38.248  1.00 37.12  ? 64  ARG B NH2 1 
ATOM   4015  N N   . GLY B 1 65  ? -25.576 40.874  35.228  1.00 32.89  ? 65  GLY B N   1 
ATOM   4016  C CA  . GLY B 1 65  ? -27.022 40.751  35.310  1.00 31.84  ? 65  GLY B CA  1 
ATOM   4017  C C   . GLY B 1 65  ? -27.765 42.086  35.440  1.00 32.22  ? 65  GLY B C   1 
ATOM   4018  O O   . GLY B 1 65  ? -28.994 42.083  35.424  1.00 38.62  ? 65  GLY B O   1 
ATOM   4019  N N   . TYR B 1 66  ? -27.053 43.212  35.582  1.00 30.60  ? 66  TYR B N   1 
ATOM   4020  C CA  . TYR B 1 66  ? -27.677 44.514  35.780  1.00 31.57  ? 66  TYR B CA  1 
ATOM   4021  C C   . TYR B 1 66  ? -27.658 45.310  34.480  1.00 32.02  ? 66  TYR B C   1 
ATOM   4022  O O   . TYR B 1 66  ? -26.699 45.231  33.712  1.00 32.74  ? 66  TYR B O   1 
ATOM   4023  C CB  . TYR B 1 66  ? -26.988 45.333  36.869  1.00 34.02  ? 66  TYR B CB  1 
ATOM   4024  C CG  . TYR B 1 66  ? -27.026 44.713  38.259  1.00 35.23  ? 66  TYR B CG  1 
ATOM   4025  C CD1 . TYR B 1 66  ? -28.091 44.937  39.130  1.00 38.99  ? 66  TYR B CD1 1 
ATOM   4026  C CD2 . TYR B 1 66  ? -25.989 43.908  38.707  1.00 36.05  ? 66  TYR B CD2 1 
ATOM   4027  C CE1 . TYR B 1 66  ? -28.124 44.360  40.394  1.00 40.25  ? 66  TYR B CE1 1 
ATOM   4028  C CE2 . TYR B 1 66  ? -25.997 43.345  39.974  1.00 34.61  ? 66  TYR B CE2 1 
ATOM   4029  C CZ  . TYR B 1 66  ? -27.069 43.561  40.818  1.00 40.10  ? 66  TYR B CZ  1 
ATOM   4030  O OH  . TYR B 1 66  ? -27.029 42.978  42.060  1.00 43.09  ? 66  TYR B OH  1 
ATOM   4031  N N   . THR B 1 67  ? -28.754 46.041  34.232  1.00 31.15  ? 67  THR B N   1 
ATOM   4032  C CA  . THR B 1 67  ? -28.898 46.842  33.029  1.00 29.81  ? 67  THR B CA  1 
ATOM   4033  C C   . THR B 1 67  ? -28.199 48.173  33.269  1.00 30.02  ? 67  THR B C   1 
ATOM   4034  O O   . THR B 1 67  ? -28.006 48.597  34.406  1.00 29.17  ? 67  THR B O   1 
ATOM   4035  C CB  . THR B 1 67  ? -30.361 47.065  32.621  1.00 28.73  ? 67  THR B CB  1 
ATOM   4036  O OG1 . THR B 1 67  ? -30.891 48.071  33.481  1.00 26.78  ? 67  THR B OG1 1 
ATOM   4037  C CG2 . THR B 1 67  ? -31.203 45.800  32.632  1.00 28.00  ? 67  THR B CG2 1 
ATOM   4038  N N   . ILE B 1 68  ? -27.906 48.861  32.173  1.00 29.97  ? 68  ILE B N   1 
ATOM   4039  C CA  . ILE B 1 68  ? -27.264 50.163  32.250  1.00 31.89  ? 68  ILE B CA  1 
ATOM   4040  C C   . ILE B 1 68  ? -28.152 51.152  32.989  1.00 30.09  ? 68  ILE B C   1 
ATOM   4041  O O   . ILE B 1 68  ? -27.674 51.837  33.879  1.00 30.19  ? 68  ILE B O   1 
ATOM   4042  C CB  . ILE B 1 68  ? -26.814 50.622  30.847  1.00 32.10  ? 68  ILE B CB  1 
ATOM   4043  C CG1 . ILE B 1 68  ? -25.491 49.893  30.538  1.00 33.39  ? 68  ILE B CG1 1 
ATOM   4044  C CG2 . ILE B 1 68  ? -26.689 52.147  30.736  1.00 31.10  ? 68  ILE B CG2 1 
ATOM   4045  C CD1 . ILE B 1 68  ? -25.074 49.857  29.087  1.00 37.25  ? 68  ILE B CD1 1 
ATOM   4046  N N   . PRO B 1 69  ? -29.453 51.261  32.657  1.00 32.07  ? 69  PRO B N   1 
ATOM   4047  C CA  . PRO B 1 69  ? -30.370 52.076  33.466  1.00 32.36  ? 69  PRO B CA  1 
ATOM   4048  C C   . PRO B 1 69  ? -30.432 51.686  34.953  1.00 29.68  ? 69  PRO B C   1 
ATOM   4049  O O   . PRO B 1 69  ? -30.461 52.558  35.822  1.00 28.12  ? 69  PRO B O   1 
ATOM   4050  C CB  . PRO B 1 69  ? -31.774 51.946  32.751  1.00 32.97  ? 69  PRO B CB  1 
ATOM   4051  C CG  . PRO B 1 69  ? -31.500 51.261  31.407  1.00 32.01  ? 69  PRO B CG  1 
ATOM   4052  C CD  . PRO B 1 69  ? -30.095 50.643  31.481  1.00 31.91  ? 69  PRO B CD  1 
ATOM   4053  N N   . GLU B 1 70  ? -30.451 50.377  35.250  1.00 28.03  ? 70  GLU B N   1 
ATOM   4054  C CA  . GLU B 1 70  ? -30.412 49.902  36.624  1.00 28.60  ? 70  GLU B CA  1 
ATOM   4055  C C   . GLU B 1 70  ? -29.239 50.567  37.347  1.00 33.82  ? 70  GLU B C   1 
ATOM   4056  O O   . GLU B 1 70  ? -29.445 51.038  38.464  1.00 36.34  ? 70  GLU B O   1 
ATOM   4057  C CB  . GLU B 1 70  ? -30.366 48.374  36.768  1.00 31.84  ? 70  GLU B CB  1 
ATOM   4058  C CG  . GLU B 1 70  ? -31.706 47.651  36.567  1.00 35.16  ? 70  GLU B CG  1 
ATOM   4059  C CD  . GLU B 1 70  ? -31.758 46.169  36.945  1.00 41.82  ? 70  GLU B CD  1 
ATOM   4060  O OE1 . GLU B 1 70  ? -32.377 45.881  37.988  1.00 58.79  ? 70  GLU B OE1 1 
ATOM   4061  O OE2 . GLU B 1 70  ? -31.190 45.287  36.277  1.00 41.17  ? 70  GLU B OE2 1 
ATOM   4062  N N   . LEU B 1 71  ? -28.049 50.657  36.697  1.00 33.65  ? 71  LEU B N   1 
ATOM   4063  C CA  . LEU B 1 71  ? -26.820 51.161  37.313  1.00 31.43  ? 71  LEU B CA  1 
ATOM   4064  C C   . LEU B 1 71  ? -26.648 52.686  37.231  1.00 30.84  ? 71  LEU B C   1 
ATOM   4065  O O   . LEU B 1 71  ? -25.974 53.308  38.065  1.00 28.71  ? 71  LEU B O   1 
ATOM   4066  C CB  . LEU B 1 71  ? -25.658 50.429  36.659  1.00 30.19  ? 71  LEU B CB  1 
ATOM   4067  C CG  . LEU B 1 71  ? -25.690 48.915  36.866  1.00 32.95  ? 71  LEU B CG  1 
ATOM   4068  C CD1 . LEU B 1 71  ? -24.564 48.299  36.066  1.00 31.72  ? 71  LEU B CD1 1 
ATOM   4069  C CD2 . LEU B 1 71  ? -25.584 48.501  38.339  1.00 34.45  ? 71  LEU B CD2 1 
ATOM   4070  N N   . ARG B 1 72  ? -27.275 53.310  36.241  1.00 29.44  ? 72  ARG B N   1 
ATOM   4071  C CA  . ARG B 1 72  ? -27.070 54.727  36.037  1.00 29.87  ? 72  ARG B CA  1 
ATOM   4072  C C   . ARG B 1 72  ? -28.231 55.536  36.612  1.00 32.45  ? 72  ARG B C   1 
ATOM   4073  O O   . ARG B 1 72  ? -28.055 56.719  36.898  1.00 32.26  ? 72  ARG B O   1 
ATOM   4074  C CB  . ARG B 1 72  ? -26.874 54.935  34.533  1.00 29.15  ? 72  ARG B CB  1 
ATOM   4075  C CG  . ARG B 1 72  ? -26.690 56.394  34.143  1.00 30.43  ? 72  ARG B CG  1 
ATOM   4076  C CD  . ARG B 1 72  ? -26.422 56.571  32.649  1.00 31.90  ? 72  ARG B CD  1 
ATOM   4077  N NE  . ARG B 1 72  ? -26.300 57.998  32.339  1.00 30.01  ? 72  ARG B NE  1 
ATOM   4078  C CZ  . ARG B 1 72  ? -27.286 58.699  31.827  1.00 32.16  ? 72  ARG B CZ  1 
ATOM   4079  N NH1 . ARG B 1 72  ? -28.407 58.088  31.465  1.00 31.06  ? 72  ARG B NH1 1 
ATOM   4080  N NH2 . ARG B 1 72  ? -27.143 60.001  31.665  1.00 31.88  ? 72  ARG B NH2 1 
ATOM   4081  N N   . GLU B 1 73  ? -29.426 54.930  36.720  1.00 40.00  ? 73  GLU B N   1 
ATOM   4082  C CA  . GLU B 1 73  ? -30.655 55.679  36.990  1.00 44.32  ? 73  GLU B CA  1 
ATOM   4083  C C   . GLU B 1 73  ? -31.346 55.181  38.258  1.00 37.44  ? 73  GLU B C   1 
ATOM   4084  O O   . GLU B 1 73  ? -31.857 55.961  39.036  1.00 35.46  ? 73  GLU B O   1 
ATOM   4085  C CB  . GLU B 1 73  ? -31.633 55.606  35.814  1.00 45.37  ? 73  GLU B CB  1 
ATOM   4086  C CG  . GLU B 1 73  ? -31.219 56.485  34.637  1.00 53.92  ? 73  GLU B CG  1 
ATOM   4087  C CD  . GLU B 1 73  ? -32.149 56.391  33.440  1.00 55.19  ? 73  GLU B CD  1 
ATOM   4088  O OE1 . GLU B 1 73  ? -31.864 55.568  32.548  1.00 45.45  ? 73  GLU B OE1 1 
ATOM   4089  O OE2 . GLU B 1 73  ? -33.149 57.142  33.412  1.00 59.32  ? 73  GLU B OE2 1 
ATOM   4090  N N   . GLY B 1 74  ? -31.419 53.871  38.415  1.00 36.63  ? 74  GLY B N   1 
ATOM   4091  C CA  . GLY B 1 74  ? -32.008 53.282  39.596  1.00 45.12  ? 74  GLY B CA  1 
ATOM   4092  C C   . GLY B 1 74  ? -32.633 51.942  39.229  1.00 53.92  ? 74  GLY B C   1 
ATOM   4093  O O   . GLY B 1 74  ? -32.742 51.631  38.044  1.00 51.63  ? 74  GLY B O   1 
ATOM   4094  N N   . PRO B 1 75  ? -33.096 51.128  40.213  1.00 64.11  ? 75  PRO B N   1 
ATOM   4095  C CA  . PRO B 1 75  ? -33.027 51.500  41.638  1.00 60.30  ? 75  PRO B CA  1 
ATOM   4096  C C   . PRO B 1 75  ? -31.705 51.144  42.340  1.00 62.45  ? 75  PRO B C   1 
ATOM   4097  O O   . PRO B 1 75  ? -31.498 51.475  43.510  1.00 56.80  ? 75  PRO B O   1 
ATOM   4098  C CB  . PRO B 1 75  ? -34.233 50.699  42.177  1.00 58.76  ? 75  PRO B CB  1 
ATOM   4099  C CG  . PRO B 1 75  ? -34.242 49.411  41.346  1.00 56.57  ? 75  PRO B CG  1 
ATOM   4100  C CD  . PRO B 1 75  ? -33.722 49.806  39.972  1.00 54.05  ? 75  PRO B CD  1 
ATOM   4101  N N   . HIS B 1 76  ? -30.798 50.497  41.589  1.00 60.51  ? 76  HIS B N   1 
ATOM   4102  C CA  . HIS B 1 76  ? -29.546 49.949  42.097  1.00 57.03  ? 76  HIS B CA  1 
ATOM   4103  C C   . HIS B 1 76  ? -28.362 50.838  41.694  1.00 44.66  ? 76  HIS B C   1 
ATOM   4104  O O   . HIS B 1 76  ? -27.294 50.328  41.381  1.00 44.81  ? 76  HIS B O   1 
ATOM   4105  C CB  . HIS B 1 76  ? -29.333 48.553  41.483  1.00 55.91  ? 76  HIS B CB  1 
ATOM   4106  C CG  . HIS B 1 76  ? -30.240 47.448  41.955  1.00 57.99  ? 76  HIS B CG  1 
ATOM   4107  N ND1 . HIS B 1 76  ? -30.918 46.616  41.079  1.00 61.93  ? 76  HIS B ND1 1 
ATOM   4108  C CD2 . HIS B 1 76  ? -30.540 47.007  43.189  1.00 58.97  ? 76  HIS B CD2 1 
ATOM   4109  C CE1 . HIS B 1 76  ? -31.613 45.710  41.761  1.00 61.61  ? 76  HIS B CE1 1 
ATOM   4110  N NE2 . HIS B 1 76  ? -31.394 45.926  43.043  1.00 65.25  ? 76  HIS B NE2 1 
ATOM   4111  N N   . LYS B 1 77  ? -28.543 52.164  41.689  1.00 39.55  ? 77  LYS B N   1 
ATOM   4112  C CA  . LYS B 1 77  ? -27.640 53.072  40.986  1.00 34.46  ? 77  LYS B CA  1 
ATOM   4113  C C   . LYS B 1 77  ? -26.267 53.086  41.654  1.00 32.54  ? 77  LYS B C   1 
ATOM   4114  O O   . LYS B 1 77  ? -26.193 53.075  42.869  1.00 36.70  ? 77  LYS B O   1 
ATOM   4115  C CB  . LYS B 1 77  ? -28.270 54.461  41.009  1.00 34.15  ? 77  LYS B CB  1 
ATOM   4116  C CG  . LYS B 1 77  ? -27.425 55.620  40.541  1.00 36.03  ? 77  LYS B CG  1 
ATOM   4117  C CD  . LYS B 1 77  ? -28.107 56.961  40.789  1.00 33.86  ? 77  LYS B CD  1 
ATOM   4118  C CE  . LYS B 1 77  ? -27.252 58.126  40.376  1.00 38.91  ? 77  LYS B CE  1 
ATOM   4119  N NZ  . LYS B 1 77  ? -27.050 58.265  38.932  1.00 39.49  ? 77  LYS B NZ  1 
ATOM   4120  N N   . LEU B 1 78  ? -25.189 53.093  40.862  1.00 32.17  ? 78  LEU B N   1 
ATOM   4121  C CA  . LEU B 1 78  ? -23.830 53.078  41.395  1.00 33.03  ? 78  LEU B CA  1 
ATOM   4122  C C   . LEU B 1 78  ? -23.432 54.440  41.969  1.00 30.73  ? 78  LEU B C   1 
ATOM   4123  O O   . LEU B 1 78  ? -24.001 55.485  41.660  1.00 31.79  ? 78  LEU B O   1 
ATOM   4124  C CB  . LEU B 1 78  ? -22.808 52.640  40.344  1.00 31.51  ? 78  LEU B CB  1 
ATOM   4125  C CG  . LEU B 1 78  ? -22.929 51.187  39.884  1.00 31.77  ? 78  LEU B CG  1 
ATOM   4126  C CD1 . LEU B 1 78  ? -22.217 50.943  38.567  1.00 32.61  ? 78  LEU B CD1 1 
ATOM   4127  C CD2 . LEU B 1 78  ? -22.421 50.271  40.965  1.00 31.97  ? 78  LEU B CD2 1 
ATOM   4128  N N   . PRO B 1 79  ? -22.417 54.469  42.850  1.00 26.66  ? 79  PRO B N   1 
ATOM   4129  C CA  . PRO B 1 79  ? -21.913 55.732  43.362  1.00 26.06  ? 79  PRO B CA  1 
ATOM   4130  C C   . PRO B 1 79  ? -21.369 56.649  42.273  1.00 27.32  ? 79  PRO B C   1 
ATOM   4131  O O   . PRO B 1 79  ? -20.864 56.182  41.241  1.00 24.69  ? 79  PRO B O   1 
ATOM   4132  C CB  . PRO B 1 79  ? -20.841 55.263  44.316  1.00 27.77  ? 79  PRO B CB  1 
ATOM   4133  C CG  . PRO B 1 79  ? -21.320 53.910  44.746  1.00 26.93  ? 79  PRO B CG  1 
ATOM   4134  C CD  . PRO B 1 79  ? -21.796 53.297  43.471  1.00 26.73  ? 79  PRO B CD  1 
ATOM   4135  N N   . THR B 1 80  ? -21.454 57.950  42.567  1.00 26.79  ? 80  THR B N   1 
ATOM   4136  C CA  . THR B 1 80  ? -21.069 59.009  41.656  1.00 29.16  ? 80  THR B CA  1 
ATOM   4137  C C   . THR B 1 80  ? -19.923 59.766  42.304  1.00 30.86  ? 80  THR B C   1 
ATOM   4138  O O   . THR B 1 80  ? -19.527 59.457  43.408  1.00 31.76  ? 80  THR B O   1 
ATOM   4139  C CB  . THR B 1 80  ? -22.246 59.948  41.375  1.00 30.34  ? 80  THR B CB  1 
ATOM   4140  O OG1 . THR B 1 80  ? -22.545 60.694  42.554  1.00 27.73  ? 80  THR B OG1 1 
ATOM   4141  C CG2 . THR B 1 80  ? -23.502 59.232  40.915  1.00 30.67  ? 80  THR B CG2 1 
ATOM   4142  N N   . ALA B 1 81  ? -19.378 60.746  41.602  1.00 33.94  ? 81  ALA B N   1 
ATOM   4143  C CA  . ALA B 1 81  ? -18.591 61.761  42.268  1.00 34.23  ? 81  ALA B CA  1 
ATOM   4144  C C   . ALA B 1 81  ? -19.522 62.589  43.133  1.00 38.51  ? 81  ALA B C   1 
ATOM   4145  O O   . ALA B 1 81  ? -20.733 62.601  42.911  1.00 37.89  ? 81  ALA B O   1 
ATOM   4146  C CB  . ALA B 1 81  ? -17.907 62.642  41.236  1.00 36.43  ? 81  ALA B CB  1 
ATOM   4147  N N   . GLU B 1 82  ? -18.928 63.330  44.068  1.00 47.15  ? 82  GLU B N   1 
ATOM   4148  C CA  . GLU B 1 82  ? -19.668 64.255  44.907  1.00 49.97  ? 82  GLU B CA  1 
ATOM   4149  C C   . GLU B 1 82  ? -20.257 65.314  43.980  1.00 44.70  ? 82  GLU B C   1 
ATOM   4150  O O   . GLU B 1 82  ? -19.527 65.935  43.208  1.00 37.59  ? 82  GLU B O   1 
ATOM   4151  C CB  . GLU B 1 82  ? -18.782 64.841  46.013  1.00 57.08  ? 82  GLU B CB  1 
ATOM   4152  C CG  . GLU B 1 82  ? -19.514 65.093  47.334  1.00 69.98  ? 82  GLU B CG  1 
ATOM   4153  C CD  . GLU B 1 82  ? -18.695 65.859  48.371  1.00 80.75  ? 82  GLU B CD  1 
ATOM   4154  O OE1 . GLU B 1 82  ? -19.188 66.929  48.790  1.00 84.72  ? 82  GLU B OE1 1 
ATOM   4155  O OE2 . GLU B 1 82  ? -17.578 65.427  48.761  1.00 74.13  ? 82  GLU B OE2 1 
ATOM   4156  N N   . GLY B 1 83  ? -21.588 65.448  44.019  1.00 41.43  ? 83  GLY B N   1 
ATOM   4157  C CA  . GLY B 1 83  ? -22.299 66.441  43.226  1.00 40.07  ? 83  GLY B CA  1 
ATOM   4158  C C   . GLY B 1 83  ? -22.514 66.020  41.769  1.00 38.79  ? 83  GLY B C   1 
ATOM   4159  O O   . GLY B 1 83  ? -22.919 66.843  40.947  1.00 32.41  ? 83  GLY B O   1 
ATOM   4160  N N   . GLY B 1 84  ? -22.269 64.730  41.471  1.00 36.83  ? 84  GLY B N   1 
ATOM   4161  C CA  . GLY B 1 84  ? -22.336 64.219  40.118  1.00 34.67  ? 84  GLY B CA  1 
ATOM   4162  C C   . GLY B 1 84  ? -23.577 63.365  39.934  1.00 34.70  ? 84  GLY B C   1 
ATOM   4163  O O   . GLY B 1 84  ? -24.281 63.060  40.893  1.00 35.48  ? 84  GLY B O   1 
ATOM   4164  N N   . PHE B 1 85  ? -23.823 62.980  38.685  1.00 36.64  ? 85  PHE B N   1 
ATOM   4165  C CA  . PHE B 1 85  ? -24.886 62.045  38.382  1.00 37.53  ? 85  PHE B CA  1 
ATOM   4166  C C   . PHE B 1 85  ? -24.340 60.755  37.757  1.00 36.75  ? 85  PHE B C   1 
ATOM   4167  O O   . PHE B 1 85  ? -24.881 59.682  38.044  1.00 39.58  ? 85  PHE B O   1 
ATOM   4168  C CB  . PHE B 1 85  ? -25.912 62.766  37.503  1.00 36.54  ? 85  PHE B CB  1 
ATOM   4169  C CG  . PHE B 1 85  ? -27.054 61.854  37.077  1.00 37.45  ? 85  PHE B CG  1 
ATOM   4170  C CD1 . PHE B 1 85  ? -28.157 61.673  37.906  1.00 35.71  ? 85  PHE B CD1 1 
ATOM   4171  C CD2 . PHE B 1 85  ? -27.002 61.163  35.862  1.00 36.71  ? 85  PHE B CD2 1 
ATOM   4172  C CE1 . PHE B 1 85  ? -29.199 60.838  37.526  1.00 36.58  ? 85  PHE B CE1 1 
ATOM   4173  C CE2 . PHE B 1 85  ? -28.044 60.326  35.489  1.00 38.38  ? 85  PHE B CE2 1 
ATOM   4174  C CZ  . PHE B 1 85  ? -29.138 60.157  36.329  1.00 36.05  ? 85  PHE B CZ  1 
ATOM   4175  N N   . GLU B 1 86  ? -23.312 60.845  36.890  1.00 32.17  ? 86  GLU B N   1 
ATOM   4176  C CA  . GLU B 1 86  ? -22.898 59.676  36.115  1.00 30.33  ? 86  GLU B CA  1 
ATOM   4177  C C   . GLU B 1 86  ? -22.167 58.672  37.000  1.00 25.95  ? 86  GLU B C   1 
ATOM   4178  O O   . GLU B 1 86  ? -21.375 59.047  37.860  1.00 28.83  ? 86  GLU B O   1 
ATOM   4179  C CB  . GLU B 1 86  ? -22.042 60.073  34.912  1.00 29.65  ? 86  GLU B CB  1 
ATOM   4180  C CG  . GLU B 1 86  ? -22.767 61.021  33.964  1.00 29.18  ? 86  GLU B CG  1 
ATOM   4181  C CD  . GLU B 1 86  ? -24.002 60.392  33.316  1.00 32.10  ? 86  GLU B CD  1 
ATOM   4182  O OE1 . GLU B 1 86  ? -24.854 61.224  32.901  1.00 32.03  ? 86  GLU B OE1 1 
ATOM   4183  O OE2 . GLU B 1 86  ? -24.127 59.127  33.216  1.00 25.95  ? 86  GLU B OE2 1 
ATOM   4184  N N   . PRO B 1 87  ? -22.359 57.359  36.790  1.00 24.36  ? 87  PRO B N   1 
ATOM   4185  C CA  . PRO B 1 87  ? -21.712 56.352  37.629  1.00 26.96  ? 87  PRO B CA  1 
ATOM   4186  C C   . PRO B 1 87  ? -20.197 56.407  37.460  1.00 30.62  ? 87  PRO B C   1 
ATOM   4187  O O   . PRO B 1 87  ? -19.709 56.682  36.354  1.00 30.44  ? 87  PRO B O   1 
ATOM   4188  C CB  . PRO B 1 87  ? -22.282 55.008  37.146  1.00 24.72  ? 87  PRO B CB  1 
ATOM   4189  C CG  . PRO B 1 87  ? -22.675 55.298  35.693  1.00 24.88  ? 87  PRO B CG  1 
ATOM   4190  C CD  . PRO B 1 87  ? -23.129 56.756  35.699  1.00 25.56  ? 87  PRO B CD  1 
ATOM   4191  N N   . LEU B 1 88  ? -19.480 56.118  38.560  1.00 31.14  ? 88  LEU B N   1 
ATOM   4192  C CA  . LEU B 1 88  ? -18.027 56.014  38.529  1.00 29.54  ? 88  LEU B CA  1 
ATOM   4193  C C   . LEU B 1 88  ? -17.632 54.616  38.078  1.00 27.10  ? 88  LEU B C   1 
ATOM   4194  O O   . LEU B 1 88  ? -18.147 53.624  38.571  1.00 27.13  ? 88  LEU B O   1 
ATOM   4195  C CB  . LEU B 1 88  ? -17.390 56.346  39.874  1.00 30.30  ? 88  LEU B CB  1 
ATOM   4196  C CG  . LEU B 1 88  ? -17.507 57.802  40.345  1.00 33.87  ? 88  LEU B CG  1 
ATOM   4197  C CD1 . LEU B 1 88  ? -16.641 58.022  41.591  1.00 33.88  ? 88  LEU B CD1 1 
ATOM   4198  C CD2 . LEU B 1 88  ? -17.164 58.813  39.248  1.00 32.29  ? 88  LEU B CD2 1 
ATOM   4199  N N   . PRO B 1 89  ? -16.726 54.504  37.084  1.00 29.77  ? 89  PRO B N   1 
ATOM   4200  C CA  . PRO B 1 89  ? -16.186 53.200  36.684  1.00 30.88  ? 89  PRO B CA  1 
ATOM   4201  C C   . PRO B 1 89  ? -15.517 52.391  37.799  1.00 29.29  ? 89  PRO B C   1 
ATOM   4202  O O   . PRO B 1 89  ? -15.497 51.158  37.749  1.00 26.48  ? 89  PRO B O   1 
ATOM   4203  C CB  . PRO B 1 89  ? -15.204 53.541  35.538  1.00 30.19  ? 89  PRO B CB  1 
ATOM   4204  C CG  . PRO B 1 89  ? -15.012 55.040  35.611  1.00 29.70  ? 89  PRO B CG  1 
ATOM   4205  C CD  . PRO B 1 89  ? -16.252 55.611  36.233  1.00 29.38  ? 89  PRO B CD  1 
ATOM   4206  N N   . GLU B 1 90  ? -14.945 53.091  38.782  1.00 26.85  ? 90  GLU B N   1 
ATOM   4207  C CA  . GLU B 1 90  ? -14.413 52.417  39.954  1.00 28.53  ? 90  GLU B CA  1 
ATOM   4208  C C   . GLU B 1 90  ? -15.484 51.481  40.506  1.00 28.71  ? 90  GLU B C   1 
ATOM   4209  O O   . GLU B 1 90  ? -15.279 50.288  40.701  1.00 26.52  ? 90  GLU B O   1 
ATOM   4210  C CB  . GLU B 1 90  ? -13.983 53.463  40.984  1.00 29.44  ? 90  GLU B CB  1 
ATOM   4211  C CG  . GLU B 1 90  ? -12.766 54.286  40.569  1.00 28.58  ? 90  GLU B CG  1 
ATOM   4212  C CD  . GLU B 1 90  ? -13.036 55.639  39.950  1.00 28.95  ? 90  GLU B CD  1 
ATOM   4213  O OE1 . GLU B 1 90  ? -12.329 56.577  40.391  1.00 30.05  ? 90  GLU B OE1 1 
ATOM   4214  O OE2 . GLU B 1 90  ? -13.907 55.776  39.069  1.00 27.64  ? 90  GLU B OE2 1 
ATOM   4215  N N   . GLY B 1 91  ? -16.665 52.048  40.719  1.00 30.59  ? 91  GLY B N   1 
ATOM   4216  C CA  . GLY B 1 91  ? -17.795 51.262  41.167  1.00 30.88  ? 91  GLY B CA  1 
ATOM   4217  C C   . GLY B 1 91  ? -18.142 50.167  40.168  1.00 31.49  ? 91  GLY B C   1 
ATOM   4218  O O   . GLY B 1 91  ? -18.419 49.028  40.573  1.00 34.08  ? 91  GLY B O   1 
ATOM   4219  N N   . LEU B 1 92  ? -18.157 50.494  38.869  1.00 28.55  ? 92  LEU B N   1 
ATOM   4220  C CA  . LEU B 1 92  ? -18.483 49.436  37.925  1.00 29.70  ? 92  LEU B CA  1 
ATOM   4221  C C   . LEU B 1 92  ? -17.482 48.277  38.036  1.00 27.66  ? 92  LEU B C   1 
ATOM   4222  O O   . LEU B 1 92  ? -17.892 47.114  38.015  1.00 23.57  ? 92  LEU B O   1 
ATOM   4223  C CB  . LEU B 1 92  ? -18.569 49.934  36.499  1.00 33.60  ? 92  LEU B CB  1 
ATOM   4224  C CG  . LEU B 1 92  ? -18.534 48.835  35.432  1.00 38.01  ? 92  LEU B CG  1 
ATOM   4225  C CD1 . LEU B 1 92  ? -19.870 48.133  35.271  1.00 40.59  ? 92  LEU B CD1 1 
ATOM   4226  C CD2 . LEU B 1 92  ? -18.109 49.444  34.148  1.00 40.63  ? 92  LEU B CD2 1 
ATOM   4227  N N   . TRP B 1 93  ? -16.181 48.608  38.141  1.00 26.42  ? 93  TRP B N   1 
ATOM   4228  C CA  . TRP B 1 93  ? -15.128 47.611  38.219  1.00 27.29  ? 93  TRP B CA  1 
ATOM   4229  C C   . TRP B 1 93  ? -15.371 46.660  39.388  1.00 27.44  ? 93  TRP B C   1 
ATOM   4230  O O   . TRP B 1 93  ? -15.284 45.432  39.211  1.00 23.68  ? 93  TRP B O   1 
ATOM   4231  C CB  . TRP B 1 93  ? -13.756 48.268  38.357  1.00 30.33  ? 93  TRP B CB  1 
ATOM   4232  C CG  . TRP B 1 93  ? -12.611 47.351  38.026  1.00 28.38  ? 93  TRP B CG  1 
ATOM   4233  C CD1 . TRP B 1 93  ? -12.424 46.629  36.887  1.00 28.49  ? 93  TRP B CD1 1 
ATOM   4234  C CD2 . TRP B 1 93  ? -11.470 47.085  38.858  1.00 28.86  ? 93  TRP B CD2 1 
ATOM   4235  N NE1 . TRP B 1 93  ? -11.246 45.926  36.950  1.00 30.12  ? 93  TRP B NE1 1 
ATOM   4236  C CE2 . TRP B 1 93  ? -10.645 46.186  38.147  1.00 28.67  ? 93  TRP B CE2 1 
ATOM   4237  C CE3 . TRP B 1 93  ? -11.078 47.516  40.128  1.00 29.37  ? 93  TRP B CE3 1 
ATOM   4238  C CZ2 . TRP B 1 93  ? -9.448  45.717  38.670  1.00 31.93  ? 93  TRP B CZ2 1 
ATOM   4239  C CZ3 . TRP B 1 93  ? -9.892  47.054  40.643  1.00 28.42  ? 93  TRP B CZ3 1 
ATOM   4240  C CH2 . TRP B 1 93  ? -9.092  46.164  39.927  1.00 31.48  ? 93  TRP B CH2 1 
ATOM   4241  N N   . TYR B 1 94  ? -15.719 47.235  40.557  1.00 25.78  ? 94  TYR B N   1 
ATOM   4242  C CA  . TYR B 1 94  ? -16.092 46.436  41.722  1.00 27.51  ? 94  TYR B CA  1 
ATOM   4243  C C   . TYR B 1 94  ? -17.171 45.414  41.344  1.00 29.45  ? 94  TYR B C   1 
ATOM   4244  O O   . TYR B 1 94  ? -17.041 44.220  41.637  1.00 29.47  ? 94  TYR B O   1 
ATOM   4245  C CB  . TYR B 1 94  ? -16.570 47.305  42.888  1.00 29.32  ? 94  TYR B CB  1 
ATOM   4246  C CG  . TYR B 1 94  ? -16.809 46.547  44.189  1.00 33.19  ? 94  TYR B CG  1 
ATOM   4247  C CD1 . TYR B 1 94  ? -17.977 45.836  44.403  1.00 35.08  ? 94  TYR B CD1 1 
ATOM   4248  C CD2 . TYR B 1 94  ? -15.875 46.572  45.219  1.00 36.14  ? 94  TYR B CD2 1 
ATOM   4249  C CE1 . TYR B 1 94  ? -18.183 45.125  45.576  1.00 40.62  ? 94  TYR B CE1 1 
ATOM   4250  C CE2 . TYR B 1 94  ? -16.088 45.902  46.411  1.00 38.91  ? 94  TYR B CE2 1 
ATOM   4251  C CZ  . TYR B 1 94  ? -17.242 45.167  46.592  1.00 41.05  ? 94  TYR B CZ  1 
ATOM   4252  O OH  . TYR B 1 94  ? -17.428 44.486  47.766  1.00 42.17  ? 94  TYR B OH  1 
ATOM   4253  N N   . LEU B 1 95  ? -18.233 45.894  40.679  1.00 30.69  ? 95  LEU B N   1 
ATOM   4254  C CA  . LEU B 1 95  ? -19.328 45.044  40.245  1.00 29.70  ? 95  LEU B CA  1 
ATOM   4255  C C   . LEU B 1 95  ? -18.832 43.938  39.319  1.00 30.54  ? 95  LEU B C   1 
ATOM   4256  O O   . LEU B 1 95  ? -19.108 42.771  39.564  1.00 34.70  ? 95  LEU B O   1 
ATOM   4257  C CB  . LEU B 1 95  ? -20.415 45.872  39.575  1.00 30.74  ? 95  LEU B CB  1 
ATOM   4258  C CG  . LEU B 1 95  ? -21.556 45.066  38.948  1.00 32.40  ? 95  LEU B CG  1 
ATOM   4259  C CD1 . LEU B 1 95  ? -22.238 44.187  39.992  1.00 30.53  ? 95  LEU B CD1 1 
ATOM   4260  C CD2 . LEU B 1 95  ? -22.549 45.989  38.279  1.00 32.79  ? 95  LEU B CD2 1 
ATOM   4261  N N   . LEU B 1 96  ? -18.071 44.273  38.281  1.00 32.88  ? 96  LEU B N   1 
ATOM   4262  C CA  . LEU B 1 96  ? -17.623 43.264  37.320  1.00 35.12  ? 96  LEU B CA  1 
ATOM   4263  C C   . LEU B 1 96  ? -16.922 42.099  38.029  1.00 32.66  ? 96  LEU B C   1 
ATOM   4264  O O   . LEU B 1 96  ? -17.146 40.940  37.705  1.00 31.66  ? 96  LEU B O   1 
ATOM   4265  C CB  . LEU B 1 96  ? -16.701 43.904  36.274  1.00 35.95  ? 96  LEU B CB  1 
ATOM   4266  C CG  . LEU B 1 96  ? -17.280 45.042  35.419  1.00 35.28  ? 96  LEU B CG  1 
ATOM   4267  C CD1 . LEU B 1 96  ? -16.348 45.308  34.251  1.00 35.46  ? 96  LEU B CD1 1 
ATOM   4268  C CD2 . LEU B 1 96  ? -18.693 44.810  34.862  1.00 32.87  ? 96  LEU B CD2 1 
ATOM   4269  N N   . LEU B 1 97  ? -16.069 42.427  39.005  1.00 33.98  ? 97  LEU B N   1 
ATOM   4270  C CA  . LEU B 1 97  ? -15.216 41.472  39.689  1.00 31.98  ? 97  LEU B CA  1 
ATOM   4271  C C   . LEU B 1 97  ? -15.987 40.599  40.679  1.00 34.16  ? 97  LEU B C   1 
ATOM   4272  O O   . LEU B 1 97  ? -15.754 39.386  40.681  1.00 33.81  ? 97  LEU B O   1 
ATOM   4273  C CB  . LEU B 1 97  ? -14.121 42.238  40.422  1.00 31.03  ? 97  LEU B CB  1 
ATOM   4274  C CG  . LEU B 1 97  ? -12.832 42.468  39.644  1.00 30.01  ? 97  LEU B CG  1 
ATOM   4275  C CD1 . LEU B 1 97  ? -12.001 43.525  40.335  1.00 32.37  ? 97  LEU B CD1 1 
ATOM   4276  C CD2 . LEU B 1 97  ? -12.061 41.167  39.506  1.00 28.70  ? 97  LEU B CD2 1 
ATOM   4277  N N   . THR B 1 98  ? -16.836 41.210  41.541  1.00 31.76  ? 98  THR B N   1 
ATOM   4278  C CA  . THR B 1 98  ? -17.519 40.481  42.621  1.00 32.18  ? 98  THR B CA  1 
ATOM   4279  C C   . THR B 1 98  ? -18.885 39.938  42.213  1.00 32.62  ? 98  THR B C   1 
ATOM   4280  O O   . THR B 1 98  ? -19.335 38.948  42.771  1.00 37.03  ? 98  THR B O   1 
ATOM   4281  C CB  . THR B 1 98  ? -17.693 41.351  43.860  1.00 31.20  ? 98  THR B CB  1 
ATOM   4282  O OG1 . THR B 1 98  ? -18.557 42.447  43.589  1.00 30.57  ? 98  THR B OG1 1 
ATOM   4283  C CG2 . THR B 1 98  ? -16.374 41.915  44.351  1.00 33.49  ? 98  THR B CG2 1 
ATOM   4284  N N   . GLY B 1 99  ? -19.556 40.607  41.272  1.00 34.80  ? 99  GLY B N   1 
ATOM   4285  C CA  . GLY B 1 99  ? -20.938 40.302  40.926  1.00 34.54  ? 99  GLY B CA  1 
ATOM   4286  C C   . GLY B 1 99  ? -21.916 40.967  41.893  1.00 33.46  ? 99  GLY B C   1 
ATOM   4287  O O   . GLY B 1 99  ? -23.103 40.664  41.871  1.00 39.13  ? 99  GLY B O   1 
ATOM   4288  N N   . GLU B 1 100 ? -21.395 41.888  42.712  1.00 31.61  ? 100 GLU B N   1 
ATOM   4289  C CA  . GLU B 1 100 ? -22.120 42.506  43.803  1.00 32.12  ? 100 GLU B CA  1 
ATOM   4290  C C   . GLU B 1 100 ? -21.975 44.012  43.655  1.00 34.35  ? 100 GLU B C   1 
ATOM   4291  O O   . GLU B 1 100 ? -20.999 44.501  43.108  1.00 38.69  ? 100 GLU B O   1 
ATOM   4292  C CB  . GLU B 1 100 ? -21.573 42.043  45.156  1.00 32.77  ? 100 GLU B CB  1 
ATOM   4293  C CG  . GLU B 1 100 ? -21.537 40.519  45.295  1.00 35.10  ? 100 GLU B CG  1 
ATOM   4294  C CD  . GLU B 1 100 ? -20.927 39.904  46.560  1.00 38.11  ? 100 GLU B CD  1 
ATOM   4295  O OE1 . GLU B 1 100 ? -21.251 38.705  46.762  1.00 39.12  ? 100 GLU B OE1 1 
ATOM   4296  O OE2 . GLU B 1 100 ? -20.153 40.558  47.316  1.00 31.73  ? 100 GLU B OE2 1 
ATOM   4297  N N   . LEU B 1 101 ? -22.970 44.753  44.125  1.00 35.88  ? 101 LEU B N   1 
ATOM   4298  C CA  . LEU B 1 101 ? -22.947 46.200  44.016  1.00 34.68  ? 101 LEU B CA  1 
ATOM   4299  C C   . LEU B 1 101 ? -22.064 46.798  45.106  1.00 32.80  ? 101 LEU B C   1 
ATOM   4300  O O   . LEU B 1 101 ? -22.176 46.457  46.270  1.00 33.36  ? 101 LEU B O   1 
ATOM   4301  C CB  . LEU B 1 101 ? -24.391 46.686  44.117  1.00 32.51  ? 101 LEU B CB  1 
ATOM   4302  C CG  . LEU B 1 101 ? -25.277 46.306  42.934  1.00 37.39  ? 101 LEU B CG  1 
ATOM   4303  C CD1 . LEU B 1 101 ? -26.771 46.497  43.203  1.00 35.19  ? 101 LEU B CD1 1 
ATOM   4304  C CD2 . LEU B 1 101 ? -24.815 47.124  41.705  1.00 40.75  ? 101 LEU B CD2 1 
ATOM   4305  N N   . PRO B 1 102 ? -21.190 47.756  44.781  1.00 34.42  ? 102 PRO B N   1 
ATOM   4306  C CA  . PRO B 1 102 ? -20.361 48.395  45.803  1.00 36.09  ? 102 PRO B CA  1 
ATOM   4307  C C   . PRO B 1 102 ? -21.106 49.398  46.674  1.00 37.03  ? 102 PRO B C   1 
ATOM   4308  O O   . PRO B 1 102 ? -21.953 50.117  46.159  1.00 42.49  ? 102 PRO B O   1 
ATOM   4309  C CB  . PRO B 1 102 ? -19.326 49.106  44.913  1.00 36.04  ? 102 PRO B CB  1 
ATOM   4310  C CG  . PRO B 1 102 ? -20.132 49.513  43.699  1.00 35.45  ? 102 PRO B CG  1 
ATOM   4311  C CD  . PRO B 1 102 ? -20.954 48.265  43.425  1.00 35.07  ? 102 PRO B CD  1 
ATOM   4312  N N   . THR B 1 103 ? -20.715 49.489  47.957  1.00 38.43  ? 103 THR B N   1 
ATOM   4313  C CA  . THR B 1 103 ? -21.078 50.592  48.847  1.00 38.05  ? 103 THR B CA  1 
ATOM   4314  C C   . THR B 1 103 ? -20.276 51.842  48.485  1.00 36.38  ? 103 THR B C   1 
ATOM   4315  O O   . THR B 1 103 ? -19.355 51.804  47.668  1.00 35.24  ? 103 THR B O   1 
ATOM   4316  C CB  . THR B 1 103 ? -20.836 50.212  50.314  1.00 37.94  ? 103 THR B CB  1 
ATOM   4317  O OG1 . THR B 1 103 ? -19.441 49.998  50.529  1.00 42.25  ? 103 THR B OG1 1 
ATOM   4318  C CG2 . THR B 1 103 ? -21.574 48.943  50.707  1.00 36.04  ? 103 THR B CG2 1 
ATOM   4319  N N   . GLU B 1 104 ? -20.612 52.965  49.113  1.00 37.98  ? 104 GLU B N   1 
ATOM   4320  C CA  . GLU B 1 104 ? -19.910 54.199  48.806  1.00 41.34  ? 104 GLU B CA  1 
ATOM   4321  C C   . GLU B 1 104 ? -18.431 54.039  49.171  1.00 42.02  ? 104 GLU B C   1 
ATOM   4322  O O   . GLU B 1 104 ? -17.560 54.589  48.494  1.00 44.71  ? 104 GLU B O   1 
ATOM   4323  C CB  . GLU B 1 104 ? -20.629 55.392  49.442  1.00 41.69  ? 104 GLU B CB  1 
ATOM   4324  C CG  . GLU B 1 104 ? -21.853 55.876  48.661  1.00 44.95  ? 104 GLU B CG  1 
ATOM   4325  C CD  . GLU B 1 104 ? -21.605 56.950  47.600  1.00 48.25  ? 104 GLU B CD  1 
ATOM   4326  O OE1 . GLU B 1 104 ? -22.600 57.381  46.945  1.00 48.35  ? 104 GLU B OE1 1 
ATOM   4327  O OE2 . GLU B 1 104 ? -20.426 57.375  47.430  1.00 44.57  ? 104 GLU B OE2 1 
ATOM   4328  N N   . GLU B 1 105 ? -18.159 53.260  50.225  1.00 46.19  ? 105 GLU B N   1 
ATOM   4329  C CA  . GLU B 1 105 ? -16.823 53.138  50.794  1.00 52.49  ? 105 GLU B CA  1 
ATOM   4330  C C   . GLU B 1 105 ? -15.969 52.212  49.922  1.00 45.61  ? 105 GLU B C   1 
ATOM   4331  O O   . GLU B 1 105 ? -14.814 52.516  49.642  1.00 42.56  ? 105 GLU B O   1 
ATOM   4332  C CB  . GLU B 1 105 ? -16.851 52.650  52.248  1.00 59.36  ? 105 GLU B CB  1 
ATOM   4333  C CG  . GLU B 1 105 ? -16.191 53.615  53.239  1.00 76.69  ? 105 GLU B CG  1 
ATOM   4334  C CD  . GLU B 1 105 ? -14.769 54.146  53.002  1.00 93.83  ? 105 GLU B CD  1 
ATOM   4335  O OE1 . GLU B 1 105 ? -14.641 55.362  52.681  1.00 92.25  ? 105 GLU B OE1 1 
ATOM   4336  O OE2 . GLU B 1 105 ? -13.778 53.387  53.195  1.00 89.01  ? 105 GLU B OE2 1 
ATOM   4337  N N   . ASP B 1 106 ? -16.532 51.083  49.495  1.00 36.92  ? 106 ASP B N   1 
ATOM   4338  C CA  . ASP B 1 106 ? -15.858 50.239  48.522  1.00 41.55  ? 106 ASP B CA  1 
ATOM   4339  C C   . ASP B 1 106 ? -15.268 51.080  47.389  1.00 40.09  ? 106 ASP B C   1 
ATOM   4340  O O   . ASP B 1 106 ? -14.159 50.805  46.931  1.00 34.90  ? 106 ASP B O   1 
ATOM   4341  C CB  . ASP B 1 106 ? -16.822 49.230  47.919  1.00 44.60  ? 106 ASP B CB  1 
ATOM   4342  C CG  . ASP B 1 106 ? -17.403 48.231  48.904  1.00 44.65  ? 106 ASP B CG  1 
ATOM   4343  O OD1 . ASP B 1 106 ? -16.741 47.982  49.932  1.00 45.00  ? 106 ASP B OD1 1 
ATOM   4344  O OD2 . ASP B 1 106 ? -18.530 47.761  48.653  1.00 46.31  ? 106 ASP B OD2 1 
ATOM   4345  N N   . VAL B 1 107 ? -16.046 52.080  46.934  1.00 36.68  ? 107 VAL B N   1 
ATOM   4346  C CA  . VAL B 1 107 ? -15.704 52.886  45.782  1.00 37.70  ? 107 VAL B CA  1 
ATOM   4347  C C   . VAL B 1 107 ? -14.559 53.827  46.171  1.00 39.14  ? 107 VAL B C   1 
ATOM   4348  O O   . VAL B 1 107 ? -13.631 53.988  45.396  1.00 40.21  ? 107 VAL B O   1 
ATOM   4349  C CB  . VAL B 1 107 ? -16.929 53.612  45.170  1.00 39.01  ? 107 VAL B CB  1 
ATOM   4350  C CG1 . VAL B 1 107 ? -16.551 54.686  44.154  1.00 43.79  ? 107 VAL B CG1 1 
ATOM   4351  C CG2 . VAL B 1 107 ? -17.901 52.650  44.502  1.00 36.75  ? 107 VAL B CG2 1 
ATOM   4352  N N   . LYS B 1 108 ? -14.559 54.394  47.381  1.00 42.58  ? 108 LYS B N   1 
ATOM   4353  C CA  . LYS B 1 108 ? -13.534 55.369  47.719  1.00 43.32  ? 108 LYS B CA  1 
ATOM   4354  C C   . LYS B 1 108 ? -12.205 54.667  47.974  1.00 41.28  ? 108 LYS B C   1 
ATOM   4355  O O   . LYS B 1 108 ? -11.156 55.279  47.813  1.00 50.76  ? 108 LYS B O   1 
ATOM   4356  C CB  . LYS B 1 108 ? -14.021 56.320  48.812  1.00 50.65  ? 108 LYS B CB  1 
ATOM   4357  C CG  . LYS B 1 108 ? -15.042 57.313  48.268  1.00 62.70  ? 108 LYS B CG  1 
ATOM   4358  C CD  . LYS B 1 108 ? -16.247 57.600  49.167  1.00 79.62  ? 108 LYS B CD  1 
ATOM   4359  C CE  . LYS B 1 108 ? -15.930 58.211  50.510  1.00 89.13  ? 108 LYS B CE  1 
ATOM   4360  N NZ  . LYS B 1 108 ? -15.387 59.572  50.427  1.00 89.68  ? 108 LYS B NZ  1 
ATOM   4361  N N   . GLU B 1 109 ? -12.241 53.384  48.327  1.00 39.74  ? 109 GLU B N   1 
ATOM   4362  C CA  . GLU B 1 109 ? -11.029 52.593  48.480  1.00 40.13  ? 109 GLU B CA  1 
ATOM   4363  C C   . GLU B 1 109 ? -10.385 52.339  47.115  1.00 39.61  ? 109 GLU B C   1 
ATOM   4364  O O   . GLU B 1 109 ? -9.171  52.412  46.970  1.00 39.25  ? 109 GLU B O   1 
ATOM   4365  C CB  . GLU B 1 109 ? -11.318 51.233  49.115  1.00 42.70  ? 109 GLU B CB  1 
ATOM   4366  C CG  . GLU B 1 109 ? -11.721 51.256  50.591  1.00 44.36  ? 109 GLU B CG  1 
ATOM   4367  C CD  . GLU B 1 109 ? -12.131 49.900  51.170  1.00 48.84  ? 109 GLU B CD  1 
ATOM   4368  O OE1 . GLU B 1 109 ? -12.285 49.899  52.405  1.00 51.69  ? 109 GLU B OE1 1 
ATOM   4369  O OE2 . GLU B 1 109 ? -12.285 48.863  50.452  1.00 50.95  ? 109 GLU B OE2 1 
ATOM   4370  N N   . ILE B 1 110 ? -11.210 52.040  46.109  1.00 37.59  ? 110 ILE B N   1 
ATOM   4371  C CA  . ILE B 1 110 ? -10.722 51.865  44.751  1.00 36.70  ? 110 ILE B CA  1 
ATOM   4372  C C   . ILE B 1 110 ? -10.219 53.204  44.204  1.00 37.60  ? 110 ILE B C   1 
ATOM   4373  O O   . ILE B 1 110 ? -9.124  53.269  43.654  1.00 42.35  ? 110 ILE B O   1 
ATOM   4374  C CB  . ILE B 1 110 ? -11.806 51.210  43.876  1.00 31.95  ? 110 ILE B CB  1 
ATOM   4375  C CG1 . ILE B 1 110 ? -11.953 49.730  44.228  1.00 35.26  ? 110 ILE B CG1 1 
ATOM   4376  C CG2 . ILE B 1 110 ? -11.511 51.370  42.394  1.00 28.98  ? 110 ILE B CG2 1 
ATOM   4377  C CD1 . ILE B 1 110 ? -13.310 49.149  43.873  1.00 34.52  ? 110 ILE B CD1 1 
ATOM   4378  N N   . SER B 1 111 ? -10.990 54.282  44.374  1.00 33.61  ? 111 SER B N   1 
ATOM   4379  C CA  . SER B 1 111 ? -10.523 55.589  43.946  1.00 33.24  ? 111 SER B CA  1 
ATOM   4380  C C   . SER B 1 111 ? -9.196  55.926  44.618  1.00 36.43  ? 111 SER B C   1 
ATOM   4381  O O   . SER B 1 111 ? -8.381  56.584  44.004  1.00 42.07  ? 111 SER B O   1 
ATOM   4382  C CB  . SER B 1 111 ? -11.534 56.684  44.163  1.00 32.33  ? 111 SER B CB  1 
ATOM   4383  O OG  . SER B 1 111 ? -12.511 56.710  43.123  1.00 35.10  ? 111 SER B OG  1 
ATOM   4384  N N   . ALA B 1 112 ? -8.970  55.487  45.861  1.00 41.21  ? 112 ALA B N   1 
ATOM   4385  C CA  . ALA B 1 112 ? -7.756  55.857  46.582  1.00 45.42  ? 112 ALA B CA  1 
ATOM   4386  C C   . ALA B 1 112 ? -6.584  54.982  46.124  1.00 43.43  ? 112 ALA B C   1 
ATOM   4387  O O   . ALA B 1 112 ? -5.455  55.452  45.980  1.00 40.86  ? 112 ALA B O   1 
ATOM   4388  C CB  . ALA B 1 112 ? -7.973  55.775  48.088  1.00 44.82  ? 112 ALA B CB  1 
ATOM   4389  N N   . GLU B 1 113 ? -6.854  53.707  45.846  1.00 39.47  ? 113 GLU B N   1 
ATOM   4390  C CA  . GLU B 1 113 ? -5.797  52.823  45.394  1.00 36.20  ? 113 GLU B CA  1 
ATOM   4391  C C   . GLU B 1 113 ? -5.272  53.313  44.037  1.00 40.17  ? 113 GLU B C   1 
ATOM   4392  O O   . GLU B 1 113 ? -4.061  53.275  43.771  1.00 34.68  ? 113 GLU B O   1 
ATOM   4393  C CB  . GLU B 1 113 ? -6.404  51.429  45.414  1.00 35.68  ? 113 GLU B CB  1 
ATOM   4394  C CG  . GLU B 1 113 ? -5.359  50.350  45.601  1.00 41.32  ? 113 GLU B CG  1 
ATOM   4395  C CD  . GLU B 1 113 ? -4.764  50.345  46.989  1.00 42.99  ? 113 GLU B CD  1 
ATOM   4396  O OE1 . GLU B 1 113 ? -3.625  50.823  47.188  1.00 48.96  ? 113 GLU B OE1 1 
ATOM   4397  O OE2 . GLU B 1 113 ? -5.469  49.836  47.871  1.00 42.06  ? 113 GLU B OE2 1 
ATOM   4398  N N   . PHE B 1 114 ? -6.185  53.816  43.191  1.00 36.43  ? 114 PHE B N   1 
ATOM   4399  C CA  . PHE B 1 114 ? -5.804  54.266  41.865  1.00 39.04  ? 114 PHE B CA  1 
ATOM   4400  C C   . PHE B 1 114 ? -5.017  55.570  41.989  1.00 45.19  ? 114 PHE B C   1 
ATOM   4401  O O   . PHE B 1 114 ? -4.019  55.748  41.289  1.00 47.45  ? 114 PHE B O   1 
ATOM   4402  C CB  . PHE B 1 114 ? -6.970  54.426  40.880  1.00 33.90  ? 114 PHE B CB  1 
ATOM   4403  C CG  . PHE B 1 114 ? -7.660  53.154  40.397  1.00 32.26  ? 114 PHE B CG  1 
ATOM   4404  C CD1 . PHE B 1 114 ? -7.036  51.910  40.433  1.00 33.45  ? 114 PHE B CD1 1 
ATOM   4405  C CD2 . PHE B 1 114 ? -8.945  53.210  39.882  1.00 30.75  ? 114 PHE B CD2 1 
ATOM   4406  C CE1 . PHE B 1 114 ? -7.685  50.764  39.991  1.00 31.64  ? 114 PHE B CE1 1 
ATOM   4407  C CE2 . PHE B 1 114 ? -9.579  52.062  39.423  1.00 32.20  ? 114 PHE B CE2 1 
ATOM   4408  C CZ  . PHE B 1 114 ? -8.954  50.842  39.489  1.00 30.99  ? 114 PHE B CZ  1 
ATOM   4409  N N   . THR B 1 115 ? -5.457  56.465  42.876  1.00 44.69  ? 115 THR B N   1 
ATOM   4410  C CA  . THR B 1 115 ? -4.860  57.790  43.008  1.00 55.18  ? 115 THR B CA  1 
ATOM   4411  C C   . THR B 1 115 ? -3.423  57.669  43.537  1.00 52.56  ? 115 THR B C   1 
ATOM   4412  O O   . THR B 1 115 ? -2.522  58.374  43.084  1.00 50.63  ? 115 THR B O   1 
ATOM   4413  C CB  . THR B 1 115 ? -5.767  58.658  43.900  1.00 65.42  ? 115 THR B CB  1 
ATOM   4414  O OG1 . THR B 1 115 ? -6.767  59.229  43.050  1.00 55.66  ? 115 THR B OG1 1 
ATOM   4415  C CG2 . THR B 1 115 ? -5.028  59.755  44.661  1.00 66.65  ? 115 THR B CG2 1 
ATOM   4416  N N   . LYS B 1 116 ? -3.215  56.776  44.506  1.00 49.30  ? 116 LYS B N   1 
ATOM   4417  C CA  . LYS B 1 116 ? -1.882  56.459  44.982  1.00 52.83  ? 116 LYS B CA  1 
ATOM   4418  C C   . LYS B 1 116 ? -1.020  55.984  43.810  1.00 45.73  ? 116 LYS B C   1 
ATOM   4419  O O   . LYS B 1 116 ? 0.030   56.565  43.550  1.00 43.18  ? 116 LYS B O   1 
ATOM   4420  C CB  . LYS B 1 116 ? -1.941  55.414  46.106  1.00 60.15  ? 116 LYS B CB  1 
ATOM   4421  C CG  . LYS B 1 116 ? -0.596  55.061  46.745  1.00 71.88  ? 116 LYS B CG  1 
ATOM   4422  C CD  . LYS B 1 116 ? -0.477  53.627  47.266  1.00 83.88  ? 116 LYS B CD  1 
ATOM   4423  C CE  . LYS B 1 116 ? 0.959   53.142  47.309  1.00 90.17  ? 116 LYS B CE  1 
ATOM   4424  N NZ  . LYS B 1 116 ? 1.076   51.727  46.936  1.00 88.95  ? 116 LYS B NZ  1 
ATOM   4425  N N   . ARG B 1 117 ? -1.483  54.958  43.081  1.00 39.11  ? 117 ARG B N   1 
ATOM   4426  C CA  . ARG B 1 117 ? -0.621  54.180  42.199  1.00 36.31  ? 117 ARG B CA  1 
ATOM   4427  C C   . ARG B 1 117 ? -0.431  54.899  40.872  1.00 34.87  ? 117 ARG B C   1 
ATOM   4428  O O   . ARG B 1 117 ? 0.319   54.439  40.013  1.00 39.25  ? 117 ARG B O   1 
ATOM   4429  C CB  . ARG B 1 117 ? -1.175  52.779  41.936  1.00 35.26  ? 117 ARG B CB  1 
ATOM   4430  C CG  . ARG B 1 117 ? -1.304  51.941  43.201  1.00 36.99  ? 117 ARG B CG  1 
ATOM   4431  C CD  . ARG B 1 117 ? -2.173  50.701  43.031  1.00 37.11  ? 117 ARG B CD  1 
ATOM   4432  N NE  . ARG B 1 117 ? -2.281  49.946  44.288  1.00 39.13  ? 117 ARG B NE  1 
ATOM   4433  C CZ  . ARG B 1 117 ? -1.760  48.757  44.549  1.00 38.78  ? 117 ARG B CZ  1 
ATOM   4434  N NH1 . ARG B 1 117 ? -0.903  48.207  43.717  1.00 43.04  ? 117 ARG B NH1 1 
ATOM   4435  N NH2 . ARG B 1 117 ? -2.070  48.118  45.659  1.00 40.37  ? 117 ARG B NH2 1 
ATOM   4436  N N   . MET B 1 118 ? -1.112  56.036  40.739  1.00 37.21  ? 118 MET B N   1 
ATOM   4437  C CA  . MET B 1 118 ? -1.033  56.891  39.567  1.00 37.15  ? 118 MET B CA  1 
ATOM   4438  C C   . MET B 1 118 ? 0.215   57.773  39.682  1.00 35.31  ? 118 MET B C   1 
ATOM   4439  O O   . MET B 1 118 ? 0.610   58.400  38.708  1.00 41.16  ? 118 MET B O   1 
ATOM   4440  C CB  . MET B 1 118 ? -2.324  57.720  39.473  1.00 38.15  ? 118 MET B CB  1 
ATOM   4441  C CG  . MET B 1 118 ? -2.639  58.271  38.112  1.00 39.42  ? 118 MET B CG  1 
ATOM   4442  S SD  . MET B 1 118 ? -4.156  59.246  38.022  1.00 37.62  ? 118 MET B SD  1 
ATOM   4443  C CE  . MET B 1 118 ? -5.328  57.937  37.656  1.00 42.55  ? 118 MET B CE  1 
ATOM   4444  N N   . GLN B 1 119 ? 0.828   57.815  40.871  1.00 31.44  ? 119 GLN B N   1 
ATOM   4445  C CA  . GLN B 1 119 ? 2.103   58.486  41.073  1.00 34.58  ? 119 GLN B CA  1 
ATOM   4446  C C   . GLN B 1 119 ? 3.270   57.518  40.854  1.00 34.43  ? 119 GLN B C   1 
ATOM   4447  O O   . GLN B 1 119 ? 4.412   57.940  40.936  1.00 35.28  ? 119 GLN B O   1 
ATOM   4448  C CB  . GLN B 1 119 ? 2.288   58.983  42.512  1.00 39.56  ? 119 GLN B CB  1 
ATOM   4449  C CG  . GLN B 1 119 ? 1.277   60.022  42.994  1.00 41.56  ? 119 GLN B CG  1 
ATOM   4450  C CD  . GLN B 1 119 ? 1.390   61.355  42.278  1.00 45.25  ? 119 GLN B CD  1 
ATOM   4451  O OE1 . GLN B 1 119 ? 2.486   61.897  42.085  1.00 43.32  ? 119 GLN B OE1 1 
ATOM   4452  N NE2 . GLN B 1 119 ? 0.260   61.901  41.851  1.00 52.43  ? 119 GLN B NE2 1 
ATOM   4453  N N   . ASN B 1 120 ? 3.003   56.231  40.572  1.00 34.58  ? 120 ASN B N   1 
ATOM   4454  C CA  . ASN B 1 120 ? 4.042   55.212  40.494  1.00 34.33  ? 120 ASN B CA  1 
ATOM   4455  C C   . ASN B 1 120 ? 4.317   54.746  39.064  1.00 30.85  ? 120 ASN B C   1 
ATOM   4456  O O   . ASN B 1 120 ? 4.677   53.582  38.865  1.00 31.24  ? 120 ASN B O   1 
ATOM   4457  C CB  . ASN B 1 120 ? 3.656   53.974  41.302  1.00 39.77  ? 120 ASN B CB  1 
ATOM   4458  C CG  . ASN B 1 120 ? 3.593   54.250  42.787  1.00 42.16  ? 120 ASN B CG  1 
ATOM   4459  O OD1 . ASN B 1 120 ? 4.098   55.283  43.254  1.00 40.90  ? 120 ASN B OD1 1 
ATOM   4460  N ND2 . ASN B 1 120 ? 2.981   53.336  43.532  1.00 42.27  ? 120 ASN B ND2 1 
ATOM   4461  N N   . VAL B 1 121 ? 4.166   55.626  38.065  1.00 31.37  ? 121 VAL B N   1 
ATOM   4462  C CA  . VAL B 1 121 ? 4.528   55.270  36.696  1.00 30.68  ? 121 VAL B CA  1 
ATOM   4463  C C   . VAL B 1 121 ? 6.045   55.444  36.578  1.00 29.39  ? 121 VAL B C   1 
ATOM   4464  O O   . VAL B 1 121 ? 6.571   56.532  36.808  1.00 28.76  ? 121 VAL B O   1 
ATOM   4465  C CB  . VAL B 1 121 ? 3.745   56.029  35.601  1.00 32.44  ? 121 VAL B CB  1 
ATOM   4466  C CG1 . VAL B 1 121 ? 4.183   55.699  34.176  1.00 34.17  ? 121 VAL B CG1 1 
ATOM   4467  C CG2 . VAL B 1 121 ? 2.252   55.755  35.709  1.00 37.09  ? 121 VAL B CG2 1 
ATOM   4468  N N   . PRO B 1 122 ? 6.804   54.360  36.290  1.00 26.76  ? 122 PRO B N   1 
ATOM   4469  C CA  . PRO B 1 122 ? 8.252   54.452  36.114  1.00 26.30  ? 122 PRO B CA  1 
ATOM   4470  C C   . PRO B 1 122 ? 8.622   55.563  35.148  1.00 26.20  ? 122 PRO B C   1 
ATOM   4471  O O   . PRO B 1 122 ? 7.935   55.754  34.133  1.00 25.47  ? 122 PRO B O   1 
ATOM   4472  C CB  . PRO B 1 122 ? 8.689   53.109  35.557  1.00 25.44  ? 122 PRO B CB  1 
ATOM   4473  C CG  . PRO B 1 122 ? 7.597   52.181  36.007  1.00 28.04  ? 122 PRO B CG  1 
ATOM   4474  C CD  . PRO B 1 122 ? 6.311   52.991  36.137  1.00 26.09  ? 122 PRO B CD  1 
ATOM   4475  N N   . GLN B 1 123 ? 9.745   56.222  35.468  1.00 25.44  ? 123 GLN B N   1 
ATOM   4476  C CA  . GLN B 1 123 ? 10.333  57.249  34.630  1.00 26.93  ? 123 GLN B CA  1 
ATOM   4477  C C   . GLN B 1 123 ? 10.691  56.646  33.279  1.00 27.66  ? 123 GLN B C   1 
ATOM   4478  O O   . GLN B 1 123 ? 10.473  57.262  32.244  1.00 31.56  ? 123 GLN B O   1 
ATOM   4479  C CB  . GLN B 1 123 ? 11.511  57.820  35.403  1.00 30.62  ? 123 GLN B CB  1 
ATOM   4480  C CG  . GLN B 1 123 ? 12.236  58.950  34.694  1.00 35.03  ? 123 GLN B CG  1 
ATOM   4481  C CD  . GLN B 1 123 ? 11.313  60.084  34.340  1.00 41.65  ? 123 GLN B CD  1 
ATOM   4482  O OE1 . GLN B 1 123 ? 10.544  60.559  35.180  1.00 47.77  ? 123 GLN B OE1 1 
ATOM   4483  N NE2 . GLN B 1 123 ? 11.346  60.502  33.081  1.00 48.64  ? 123 GLN B NE2 1 
ATOM   4484  N N   . TYR B 1 124 ? 11.182  55.405  33.269  1.00 27.95  ? 124 TYR B N   1 
ATOM   4485  C CA  . TYR B 1 124 ? 11.614  54.806  32.020  1.00 26.54  ? 124 TYR B CA  1 
ATOM   4486  C C   . TYR B 1 124 ? 10.440  54.661  31.056  1.00 27.11  ? 124 TYR B C   1 
ATOM   4487  O O   . TYR B 1 124 ? 10.659  54.676  29.845  1.00 23.40  ? 124 TYR B O   1 
ATOM   4488  C CB  . TYR B 1 124 ? 12.330  53.476  32.241  1.00 26.56  ? 124 TYR B CB  1 
ATOM   4489  C CG  . TYR B 1 124 ? 11.483  52.363  32.825  1.00 28.55  ? 124 TYR B CG  1 
ATOM   4490  C CD1 . TYR B 1 124 ? 10.663  51.578  32.023  1.00 27.27  ? 124 TYR B CD1 1 
ATOM   4491  C CD2 . TYR B 1 124 ? 11.539  52.065  34.181  1.00 30.00  ? 124 TYR B CD2 1 
ATOM   4492  C CE1 . TYR B 1 124 ? 9.895   50.554  32.558  1.00 27.96  ? 124 TYR B CE1 1 
ATOM   4493  C CE2 . TYR B 1 124 ? 10.774  51.039  34.722  1.00 29.11  ? 124 TYR B CE2 1 
ATOM   4494  C CZ  . TYR B 1 124 ? 9.920   50.306  33.920  1.00 27.47  ? 124 TYR B CZ  1 
ATOM   4495  O OH  . TYR B 1 124 ? 9.181   49.307  34.475  1.00 25.13  ? 124 TYR B OH  1 
ATOM   4496  N N   . VAL B 1 125 ? 9.212   54.464  31.571  1.00 26.79  ? 125 VAL B N   1 
ATOM   4497  C CA  . VAL B 1 125 ? 8.059   54.339  30.681  1.00 26.60  ? 125 VAL B CA  1 
ATOM   4498  C C   . VAL B 1 125 ? 7.954   55.615  29.836  1.00 27.11  ? 125 VAL B C   1 
ATOM   4499  O O   . VAL B 1 125 ? 7.756   55.540  28.629  1.00 25.36  ? 125 VAL B O   1 
ATOM   4500  C CB  . VAL B 1 125 ? 6.708   54.034  31.356  1.00 27.18  ? 125 VAL B CB  1 
ATOM   4501  C CG1 . VAL B 1 125 ? 5.529   54.136  30.386  1.00 28.25  ? 125 VAL B CG1 1 
ATOM   4502  C CG2 . VAL B 1 125 ? 6.711   52.674  32.038  1.00 27.58  ? 125 VAL B CG2 1 
ATOM   4503  N N   . PHE B 1 126 ? 8.121   56.785  30.461  1.00 26.35  ? 126 PHE B N   1 
ATOM   4504  C CA  . PHE B 1 126 ? 8.151   58.033  29.714  1.00 27.95  ? 126 PHE B CA  1 
ATOM   4505  C C   . PHE B 1 126 ? 9.322   58.064  28.722  1.00 27.08  ? 126 PHE B C   1 
ATOM   4506  O O   . PHE B 1 126 ? 9.154   58.483  27.584  1.00 27.63  ? 126 PHE B O   1 
ATOM   4507  C CB  . PHE B 1 126 ? 8.173   59.204  30.699  1.00 26.34  ? 126 PHE B CB  1 
ATOM   4508  C CG  . PHE B 1 126 ? 6.984   59.224  31.642  1.00 27.20  ? 126 PHE B CG  1 
ATOM   4509  C CD1 . PHE B 1 126 ? 5.712   59.532  31.168  1.00 27.56  ? 126 PHE B CD1 1 
ATOM   4510  C CD2 . PHE B 1 126 ? 7.140   58.949  33.002  1.00 28.47  ? 126 PHE B CD2 1 
ATOM   4511  C CE1 . PHE B 1 126 ? 4.624   59.565  32.035  1.00 26.85  ? 126 PHE B CE1 1 
ATOM   4512  C CE2 . PHE B 1 126 ? 6.050   58.981  33.865  1.00 27.25  ? 126 PHE B CE2 1 
ATOM   4513  C CZ  . PHE B 1 126 ? 4.795   59.274  33.373  1.00 28.79  ? 126 PHE B CZ  1 
ATOM   4514  N N   . ASP B 1 127 ? 10.509  57.624  29.158  1.00 26.90  ? 127 ASP B N   1 
ATOM   4515  C CA  . ASP B 1 127 ? 11.687  57.542  28.303  1.00 24.48  ? 127 ASP B CA  1 
ATOM   4516  C C   . ASP B 1 127 ? 11.323  56.788  27.025  1.00 25.14  ? 127 ASP B C   1 
ATOM   4517  O O   . ASP B 1 127 ? 11.641  57.220  25.910  1.00 26.00  ? 127 ASP B O   1 
ATOM   4518  C CB  . ASP B 1 127 ? 12.865  56.898  29.039  1.00 24.06  ? 127 ASP B CB  1 
ATOM   4519  C CG  . ASP B 1 127 ? 13.445  57.658  30.225  1.00 24.60  ? 127 ASP B CG  1 
ATOM   4520  O OD1 . ASP B 1 127 ? 13.067  58.829  30.444  1.00 27.78  ? 127 ASP B OD1 1 
ATOM   4521  O OD2 . ASP B 1 127 ? 14.283  57.090  30.935  1.00 25.79  ? 127 ASP B OD2 1 
ATOM   4522  N N   . VAL B 1 128 ? 10.637  55.658  27.204  1.00 23.21  ? 128 VAL B N   1 
ATOM   4523  C CA  . VAL B 1 128 ? 10.275  54.813  26.096  1.00 25.92  ? 128 VAL B CA  1 
ATOM   4524  C C   . VAL B 1 128 ? 9.278   55.540  25.200  1.00 28.82  ? 128 VAL B C   1 
ATOM   4525  O O   . VAL B 1 128 ? 9.459   55.585  23.992  1.00 29.77  ? 128 VAL B O   1 
ATOM   4526  C CB  . VAL B 1 128 ? 9.710   53.492  26.613  1.00 28.09  ? 128 VAL B CB  1 
ATOM   4527  C CG1 . VAL B 1 128 ? 8.898   52.796  25.530  1.00 30.00  ? 128 VAL B CG1 1 
ATOM   4528  C CG2 . VAL B 1 128 ? 10.829  52.599  27.137  1.00 28.91  ? 128 VAL B CG2 1 
ATOM   4529  N N   . LEU B 1 129 ? 8.250   56.137  25.786  1.00 26.93  ? 129 LEU B N   1 
ATOM   4530  C CA  . LEU B 1 129 ? 7.314   56.905  24.998  1.00 27.84  ? 129 LEU B CA  1 
ATOM   4531  C C   . LEU B 1 129 ? 8.060   57.988  24.201  1.00 29.98  ? 129 LEU B C   1 
ATOM   4532  O O   . LEU B 1 129 ? 7.773   58.142  23.010  1.00 30.66  ? 129 LEU B O   1 
ATOM   4533  C CB  . LEU B 1 129 ? 6.202   57.484  25.878  1.00 29.95  ? 129 LEU B CB  1 
ATOM   4534  C CG  . LEU B 1 129 ? 5.236   56.485  26.527  1.00 31.55  ? 129 LEU B CG  1 
ATOM   4535  C CD1 . LEU B 1 129 ? 4.400   57.175  27.578  1.00 31.97  ? 129 LEU B CD1 1 
ATOM   4536  C CD2 . LEU B 1 129 ? 4.318   55.813  25.517  1.00 32.72  ? 129 LEU B CD2 1 
ATOM   4537  N N   . ARG B 1 130 ? 8.990   58.750  24.817  1.00 27.06  ? 130 ARG B N   1 
ATOM   4538  C CA  . ARG B 1 130 ? 9.630   59.858  24.106  1.00 27.54  ? 130 ARG B CA  1 
ATOM   4539  C C   . ARG B 1 130 ? 10.563  59.329  23.007  1.00 27.15  ? 130 ARG B C   1 
ATOM   4540  O O   . ARG B 1 130 ? 10.825  60.032  22.039  1.00 29.67  ? 130 ARG B O   1 
ATOM   4541  C CB  . ARG B 1 130 ? 10.519  60.851  24.879  1.00 27.42  ? 130 ARG B CB  1 
ATOM   4542  C CG  . ARG B 1 130 ? 9.842   61.872  25.775  1.00 30.49  ? 130 ARG B CG  1 
ATOM   4543  C CD  . ARG B 1 130 ? 10.716  63.052  26.183  1.00 31.18  ? 130 ARG B CD  1 
ATOM   4544  N NE  . ARG B 1 130 ? 10.654  64.270  25.357  1.00 34.25  ? 130 ARG B NE  1 
ATOM   4545  C CZ  . ARG B 1 130 ? 9.574   65.072  25.116  1.00 34.67  ? 130 ARG B CZ  1 
ATOM   4546  N NH1 . ARG B 1 130 ? 9.734   66.289  24.589  1.00 31.12  ? 130 ARG B NH1 1 
ATOM   4547  N NH2 . ARG B 1 130 ? 8.341   64.702  25.458  1.00 29.80  ? 130 ARG B NH2 1 
ATOM   4548  N N   . ALA B 1 131 ? 11.084  58.107  23.154  1.00 26.94  ? 131 ALA B N   1 
ATOM   4549  C CA  . ALA B 1 131 ? 11.958  57.524  22.145  1.00 27.16  ? 131 ALA B CA  1 
ATOM   4550  C C   . ALA B 1 131 ? 11.186  57.233  20.856  1.00 28.20  ? 131 ALA B C   1 
ATOM   4551  O O   . ALA B 1 131 ? 11.783  57.127  19.790  1.00 29.12  ? 131 ALA B O   1 
ATOM   4552  C CB  . ALA B 1 131 ? 12.587  56.254  22.667  1.00 26.54  ? 131 ALA B CB  1 
ATOM   4553  N N   . MET B 1 132 ? 9.858   57.080  20.949  1.00 28.07  ? 132 MET B N   1 
ATOM   4554  C CA  . MET B 1 132 ? 9.056   56.855  19.758  1.00 27.64  ? 132 MET B CA  1 
ATOM   4555  C C   . MET B 1 132 ? 8.894   58.190  19.013  1.00 26.32  ? 132 MET B C   1 
ATOM   4556  O O   . MET B 1 132 ? 8.746   59.228  19.655  1.00 25.07  ? 132 MET B O   1 
ATOM   4557  C CB  . MET B 1 132 ? 7.737   56.197  20.146  1.00 27.56  ? 132 MET B CB  1 
ATOM   4558  C CG  . MET B 1 132 ? 7.931   54.856  20.835  1.00 28.85  ? 132 MET B CG  1 
ATOM   4559  S SD  . MET B 1 132 ? 6.364   54.211  21.464  1.00 28.53  ? 132 MET B SD  1 
ATOM   4560  C CE  . MET B 1 132 ? 6.021   53.088  20.115  1.00 27.52  ? 132 MET B CE  1 
ATOM   4561  N N   . PRO B 1 133 ? 9.013   58.245  17.660  1.00 24.24  ? 133 PRO B N   1 
ATOM   4562  C CA  . PRO B 1 133 ? 8.801   59.496  16.922  1.00 26.23  ? 133 PRO B CA  1 
ATOM   4563  C C   . PRO B 1 133 ? 7.407   60.002  17.231  1.00 24.03  ? 133 PRO B C   1 
ATOM   4564  O O   . PRO B 1 133 ? 6.490   59.199  17.366  1.00 27.06  ? 133 PRO B O   1 
ATOM   4565  C CB  . PRO B 1 133 ? 8.932   59.081  15.455  1.00 27.03  ? 133 PRO B CB  1 
ATOM   4566  C CG  . PRO B 1 133 ? 9.822   57.861  15.514  1.00 25.54  ? 133 PRO B CG  1 
ATOM   4567  C CD  . PRO B 1 133 ? 9.385   57.136  16.773  1.00 23.82  ? 133 PRO B CD  1 
ATOM   4568  N N   . VAL B 1 134 ? 7.236   61.316  17.303  1.00 23.77  ? 134 VAL B N   1 
ATOM   4569  C CA  . VAL B 1 134 ? 5.975   61.863  17.790  1.00 23.85  ? 134 VAL B CA  1 
ATOM   4570  C C   . VAL B 1 134 ? 4.871   61.603  16.792  1.00 24.31  ? 134 VAL B C   1 
ATOM   4571  O O   . VAL B 1 134 ? 3.726   61.817  17.113  1.00 24.17  ? 134 VAL B O   1 
ATOM   4572  C CB  . VAL B 1 134 ? 6.016   63.367  18.117  1.00 27.97  ? 134 VAL B CB  1 
ATOM   4573  C CG1 . VAL B 1 134 ? 6.159   64.227  16.864  1.00 28.35  ? 134 VAL B CG1 1 
ATOM   4574  C CG2 . VAL B 1 134 ? 4.813   63.797  18.953  1.00 27.71  ? 134 VAL B CG2 1 
ATOM   4575  N N   . ASP B 1 135 ? 5.219   61.154  15.584  1.00 27.71  ? 135 ASP B N   1 
ATOM   4576  C CA  . ASP B 1 135 ? 4.224   60.923  14.563  1.00 25.33  ? 135 ASP B CA  1 
ATOM   4577  C C   . ASP B 1 135 ? 3.752   59.478  14.635  1.00 26.81  ? 135 ASP B C   1 
ATOM   4578  O O   . ASP B 1 135 ? 2.878   59.104  13.846  1.00 27.91  ? 135 ASP B O   1 
ATOM   4579  C CB  . ASP B 1 135 ? 4.715   61.371  13.195  1.00 27.42  ? 135 ASP B CB  1 
ATOM   4580  C CG  . ASP B 1 135 ? 5.858   60.548  12.621  1.00 28.68  ? 135 ASP B CG  1 
ATOM   4581  O OD1 . ASP B 1 135 ? 6.383   59.715  13.411  1.00 27.97  ? 135 ASP B OD1 1 
ATOM   4582  O OD2 . ASP B 1 135 ? 6.201   60.747  11.403  1.00 24.05  ? 135 ASP B OD2 1 
ATOM   4583  N N   . THR B 1 136 ? 4.259   58.689  15.606  1.00 25.60  ? 136 THR B N   1 
ATOM   4584  C CA  . THR B 1 136 ? 3.816   57.301  15.762  1.00 25.55  ? 136 THR B CA  1 
ATOM   4585  C C   . THR B 1 136 ? 2.314   57.269  16.104  1.00 24.33  ? 136 THR B C   1 
ATOM   4586  O O   . THR B 1 136 ? 1.790   58.133  16.810  1.00 25.85  ? 136 THR B O   1 
ATOM   4587  C CB  . THR B 1 136 ? 4.711   56.596  16.791  1.00 29.36  ? 136 THR B CB  1 
ATOM   4588  O OG1 . THR B 1 136 ? 6.056   56.578  16.278  1.00 26.68  ? 136 THR B OG1 1 
ATOM   4589  C CG2 . THR B 1 136 ? 4.261   55.178  17.128  1.00 26.99  ? 136 THR B CG2 1 
ATOM   4590  N N   . HIS B 1 137 ? 1.573   56.298  15.561  1.00 23.99  ? 137 HIS B N   1 
ATOM   4591  C CA  . HIS B 1 137 ? 0.148   56.224  15.837  1.00 23.54  ? 137 HIS B CA  1 
ATOM   4592  C C   . HIS B 1 137 ? 0.001   56.131  17.350  1.00 25.76  ? 137 HIS B C   1 
ATOM   4593  O O   . HIS B 1 137 ? 0.749   55.421  18.039  1.00 25.09  ? 137 HIS B O   1 
ATOM   4594  C CB  . HIS B 1 137 ? -0.504  55.077  15.054  1.00 25.13  ? 137 HIS B CB  1 
ATOM   4595  C CG  . HIS B 1 137 ? -1.994  55.018  15.134  1.00 28.28  ? 137 HIS B CG  1 
ATOM   4596  N ND1 . HIS B 1 137 ? -2.679  54.626  16.269  1.00 32.92  ? 137 HIS B ND1 1 
ATOM   4597  C CD2 . HIS B 1 137 ? -2.944  55.341  14.238  1.00 27.59  ? 137 HIS B CD2 1 
ATOM   4598  C CE1 . HIS B 1 137 ? -3.992  54.738  16.063  1.00 30.13  ? 137 HIS B CE1 1 
ATOM   4599  N NE2 . HIS B 1 137 ? -4.175  55.185  14.843  1.00 28.74  ? 137 HIS B NE2 1 
ATOM   4600  N N   . PRO B 1 138 ? -0.990  56.826  17.934  1.00 27.54  ? 138 PRO B N   1 
ATOM   4601  C CA  . PRO B 1 138 ? -1.143  56.834  19.386  1.00 25.96  ? 138 PRO B CA  1 
ATOM   4602  C C   . PRO B 1 138 ? -1.484  55.494  20.054  1.00 27.01  ? 138 PRO B C   1 
ATOM   4603  O O   . PRO B 1 138 ? -1.168  55.272  21.225  1.00 29.18  ? 138 PRO B O   1 
ATOM   4604  C CB  . PRO B 1 138 ? -2.225  57.902  19.540  1.00 26.59  ? 138 PRO B CB  1 
ATOM   4605  C CG  . PRO B 1 138 ? -3.047  57.794  18.290  1.00 29.08  ? 138 PRO B CG  1 
ATOM   4606  C CD  . PRO B 1 138 ? -2.011  57.605  17.219  1.00 29.66  ? 138 PRO B CD  1 
ATOM   4607  N N   . MET B 1 139 ? -2.070  54.570  19.308  1.00 24.76  ? 139 MET B N   1 
ATOM   4608  C CA  . MET B 1 139 ? -2.351  53.243  19.828  1.00 26.64  ? 139 MET B CA  1 
ATOM   4609  C C   . MET B 1 139 ? -1.084  52.378  19.816  1.00 26.14  ? 139 MET B C   1 
ATOM   4610  O O   . MET B 1 139 ? -0.953  51.433  20.605  1.00 27.36  ? 139 MET B O   1 
ATOM   4611  C CB  . MET B 1 139 ? -3.487  52.568  19.032  1.00 26.59  ? 139 MET B CB  1 
ATOM   4612  C CG  . MET B 1 139 ? -4.884  53.012  19.397  1.00 24.58  ? 139 MET B CG  1 
ATOM   4613  S SD  . MET B 1 139 ? -5.306  52.617  21.101  1.00 26.05  ? 139 MET B SD  1 
ATOM   4614  C CE  . MET B 1 139 ? -5.384  50.829  20.957  1.00 27.14  ? 139 MET B CE  1 
ATOM   4615  N N   . THR B 1 140 ? -0.139  52.690  18.929  1.00 29.86  ? 140 THR B N   1 
ATOM   4616  C CA  . THR B 1 140 ? 1.207   52.117  19.009  1.00 30.17  ? 140 THR B CA  1 
ATOM   4617  C C   . THR B 1 140 ? 1.960   52.669  20.233  1.00 28.23  ? 140 THR B C   1 
ATOM   4618  O O   . THR B 1 140 ? 2.603   51.939  20.973  1.00 26.01  ? 140 THR B O   1 
ATOM   4619  C CB  . THR B 1 140 ? 1.964   52.392  17.716  1.00 27.88  ? 140 THR B CB  1 
ATOM   4620  O OG1 . THR B 1 140 ? 1.147   51.833  16.699  1.00 25.39  ? 140 THR B OG1 1 
ATOM   4621  C CG2 . THR B 1 140 ? 3.324   51.713  17.661  1.00 30.21  ? 140 THR B CG2 1 
ATOM   4622  N N   . MET B 1 141 ? 1.889   53.972  20.459  1.00 26.26  ? 141 MET B N   1 
ATOM   4623  C CA  . MET B 1 141 ? 2.521   54.537  21.634  1.00 26.32  ? 141 MET B CA  1 
ATOM   4624  C C   . MET B 1 141 ? 1.950   53.904  22.905  1.00 27.00  ? 141 MET B C   1 
ATOM   4625  O O   . MET B 1 141 ? 2.730   53.577  23.803  1.00 28.53  ? 141 MET B O   1 
ATOM   4626  C CB  . MET B 1 141 ? 2.368   56.063  21.682  1.00 25.20  ? 141 MET B CB  1 
ATOM   4627  C CG  . MET B 1 141 ? 3.092   56.798  20.568  1.00 26.15  ? 141 MET B CG  1 
ATOM   4628  S SD  . MET B 1 141 ? 2.813   58.570  20.734  1.00 26.58  ? 141 MET B SD  1 
ATOM   4629  C CE  . MET B 1 141 ? 3.854   59.205  19.430  1.00 27.80  ? 141 MET B CE  1 
ATOM   4630  N N   . PHE B 1 142 ? 0.609   53.758  22.967  1.00 24.27  ? 142 PHE B N   1 
ATOM   4631  C CA  . PHE B 1 142 ? -0.124  53.292  24.136  1.00 21.62  ? 142 PHE B CA  1 
ATOM   4632  C C   . PHE B 1 142 ? 0.247   51.852  24.450  1.00 20.43  ? 142 PHE B C   1 
ATOM   4633  O O   . PHE B 1 142 ? 0.567   51.505  25.582  1.00 23.31  ? 142 PHE B O   1 
ATOM   4634  C CB  . PHE B 1 142 ? -1.638  53.383  23.876  1.00 23.03  ? 142 PHE B CB  1 
ATOM   4635  C CG  . PHE B 1 142 ? -2.586  53.162  25.049  1.00 23.22  ? 142 PHE B CG  1 
ATOM   4636  C CD1 . PHE B 1 142 ? -2.445  53.871  26.239  1.00 27.23  ? 142 PHE B CD1 1 
ATOM   4637  C CD2 . PHE B 1 142 ? -3.613  52.238  24.977  1.00 25.21  ? 142 PHE B CD2 1 
ATOM   4638  C CE1 . PHE B 1 142 ? -3.300  53.667  27.313  1.00 26.78  ? 142 PHE B CE1 1 
ATOM   4639  C CE2 . PHE B 1 142 ? -4.483  52.048  26.049  1.00 25.31  ? 142 PHE B CE2 1 
ATOM   4640  C CZ  . PHE B 1 142 ? -4.327  52.761  27.212  1.00 25.16  ? 142 PHE B CZ  1 
ATOM   4641  N N   . ALA B 1 143 ? 0.157   50.983  23.454  1.00 19.12  ? 143 ALA B N   1 
ATOM   4642  C CA  . ALA B 1 143 ? 0.528   49.597  23.674  1.00 18.99  ? 143 ALA B CA  1 
ATOM   4643  C C   . ALA B 1 143 ? 1.980   49.455  24.127  1.00 21.77  ? 143 ALA B C   1 
ATOM   4644  O O   . ALA B 1 143 ? 2.290   48.599  24.963  1.00 25.15  ? 143 ALA B O   1 
ATOM   4645  C CB  . ALA B 1 143 ? 0.301   48.825  22.412  1.00 19.82  ? 143 ALA B CB  1 
ATOM   4646  N N   . ALA B 1 144 ? 2.876   50.269  23.549  1.00 21.08  ? 144 ALA B N   1 
ATOM   4647  C CA  . ALA B 1 144 ? 4.294   50.170  23.831  1.00 21.80  ? 144 ALA B CA  1 
ATOM   4648  C C   . ALA B 1 144 ? 4.576   50.674  25.250  1.00 23.88  ? 144 ALA B C   1 
ATOM   4649  O O   . ALA B 1 144 ? 5.373   50.075  25.960  1.00 21.66  ? 144 ALA B O   1 
ATOM   4650  C CB  . ALA B 1 144 ? 5.074   50.925  22.786  1.00 21.77  ? 144 ALA B CB  1 
ATOM   4651  N N   . GLY B 1 145 ? 3.893   51.746  25.673  1.00 23.74  ? 145 GLY B N   1 
ATOM   4652  C CA  . GLY B 1 145 ? 4.035   52.243  27.030  1.00 26.43  ? 145 GLY B CA  1 
ATOM   4653  C C   . GLY B 1 145 ? 3.696   51.153  28.051  1.00 27.25  ? 145 GLY B C   1 
ATOM   4654  O O   . GLY B 1 145 ? 4.451   50.894  28.983  1.00 28.59  ? 145 GLY B O   1 
ATOM   4655  N N   . ILE B 1 146 ? 2.556   50.500  27.826  1.00 26.82  ? 146 ILE B N   1 
ATOM   4656  C CA  . ILE B 1 146 ? 2.028   49.504  28.731  1.00 27.62  ? 146 ILE B CA  1 
ATOM   4657  C C   . ILE B 1 146 ? 3.003   48.328  28.815  1.00 26.33  ? 146 ILE B C   1 
ATOM   4658  O O   . ILE B 1 146 ? 3.333   47.881  29.905  1.00 28.48  ? 146 ILE B O   1 
ATOM   4659  C CB  . ILE B 1 146 ? 0.608   49.087  28.295  1.00 28.94  ? 146 ILE B CB  1 
ATOM   4660  C CG1 . ILE B 1 146 ? -0.368  50.273  28.310  1.00 31.29  ? 146 ILE B CG1 1 
ATOM   4661  C CG2 . ILE B 1 146 ? 0.098   47.933  29.157  1.00 29.33  ? 146 ILE B CG2 1 
ATOM   4662  C CD1 . ILE B 1 146 ? -1.649  50.051  27.515  1.00 30.77  ? 146 ILE B CD1 1 
ATOM   4663  N N   . LEU B 1 147 ? 3.445   47.826  27.662  1.00 25.19  ? 147 LEU B N   1 
ATOM   4664  C CA  . LEU B 1 147 ? 4.382   46.710  27.583  1.00 24.49  ? 147 LEU B CA  1 
ATOM   4665  C C   . LEU B 1 147 ? 5.670   47.004  28.374  1.00 23.03  ? 147 LEU B C   1 
ATOM   4666  O O   . LEU B 1 147 ? 6.191   46.130  29.081  1.00 20.85  ? 147 LEU B O   1 
ATOM   4667  C CB  . LEU B 1 147 ? 4.642   46.412  26.098  1.00 22.63  ? 147 LEU B CB  1 
ATOM   4668  C CG  . LEU B 1 147 ? 5.562   45.232  25.794  1.00 23.30  ? 147 LEU B CG  1 
ATOM   4669  C CD1 . LEU B 1 147 ? 5.253   43.932  26.529  1.00 24.78  ? 147 LEU B CD1 1 
ATOM   4670  C CD2 . LEU B 1 147 ? 5.525   44.960  24.327  1.00 24.22  ? 147 LEU B CD2 1 
ATOM   4671  N N   . ALA B 1 148 ? 6.185   48.235  28.293  1.00 22.03  ? 148 ALA B N   1 
ATOM   4672  C CA  . ALA B 1 148 ? 7.474   48.511  28.920  1.00 24.32  ? 148 ALA B CA  1 
ATOM   4673  C C   . ALA B 1 148 ? 7.331   48.321  30.433  1.00 27.02  ? 148 ALA B C   1 
ATOM   4674  O O   . ALA B 1 148 ? 8.264   47.893  31.121  1.00 24.85  ? 148 ALA B O   1 
ATOM   4675  C CB  . ALA B 1 148 ? 7.976   49.897  28.566  1.00 24.04  ? 148 ALA B CB  1 
ATOM   4676  N N   . MET B 1 149 ? 6.108   48.568  30.924  1.00 27.05  ? 149 MET B N   1 
ATOM   4677  C CA  . MET B 1 149 ? 5.848   48.540  32.348  1.00 27.19  ? 149 MET B CA  1 
ATOM   4678  C C   . MET B 1 149 ? 5.811   47.099  32.852  1.00 25.91  ? 149 MET B C   1 
ATOM   4679  O O   . MET B 1 149 ? 5.853   46.882  34.055  1.00 25.75  ? 149 MET B O   1 
ATOM   4680  C CB  . MET B 1 149 ? 4.571   49.312  32.700  1.00 27.56  ? 149 MET B CB  1 
ATOM   4681  C CG  . MET B 1 149 ? 4.530   49.751  34.139  1.00 26.49  ? 149 MET B CG  1 
ATOM   4682  S SD  . MET B 1 149 ? 3.172   50.897  34.382  1.00 28.32  ? 149 MET B SD  1 
ATOM   4683  C CE  . MET B 1 149 ? 2.892   50.781  36.152  1.00 27.79  ? 149 MET B CE  1 
ATOM   4684  N N   . GLN B 1 150 ? 5.849   46.122  31.945  1.00 25.33  ? 150 GLN B N   1 
ATOM   4685  C CA  . GLN B 1 150 ? 5.839   44.724  32.338  1.00 24.80  ? 150 GLN B CA  1 
ATOM   4686  C C   . GLN B 1 150 ? 7.014   44.403  33.258  1.00 27.59  ? 150 GLN B C   1 
ATOM   4687  O O   . GLN B 1 150 ? 6.981   43.443  34.020  1.00 27.78  ? 150 GLN B O   1 
ATOM   4688  C CB  . GLN B 1 150 ? 5.919   43.909  31.059  1.00 25.66  ? 150 GLN B CB  1 
ATOM   4689  C CG  . GLN B 1 150 ? 5.884   42.410  31.304  1.00 27.35  ? 150 GLN B CG  1 
ATOM   4690  C CD  . GLN B 1 150 ? 7.220   41.846  31.714  1.00 27.66  ? 150 GLN B CD  1 
ATOM   4691  O OE1 . GLN B 1 150 ? 8.284   42.398  31.398  1.00 24.88  ? 150 GLN B OE1 1 
ATOM   4692  N NE2 . GLN B 1 150 ? 7.144   40.718  32.405  1.00 27.51  ? 150 GLN B NE2 1 
ATOM   4693  N N   . ARG B 1 151 ? 8.077   45.202  33.189  1.00 28.58  ? 151 ARG B N   1 
ATOM   4694  C CA  . ARG B 1 151 ? 9.169   45.023  34.120  1.00 31.02  ? 151 ARG B CA  1 
ATOM   4695  C C   . ARG B 1 151 ? 8.631   44.961  35.545  1.00 29.94  ? 151 ARG B C   1 
ATOM   4696  O O   . ARG B 1 151 ? 9.192   44.236  36.368  1.00 28.82  ? 151 ARG B O   1 
ATOM   4697  C CB  . ARG B 1 151 ? 10.156  46.183  34.028  1.00 33.78  ? 151 ARG B CB  1 
ATOM   4698  C CG  . ARG B 1 151 ? 11.398  45.952  34.865  1.00 34.26  ? 151 ARG B CG  1 
ATOM   4699  C CD  . ARG B 1 151 ? 12.251  47.179  34.729  1.00 37.87  ? 151 ARG B CD  1 
ATOM   4700  N NE  . ARG B 1 151 ? 13.470  47.097  35.539  1.00 40.16  ? 151 ARG B NE  1 
ATOM   4701  C CZ  . ARG B 1 151 ? 13.704  47.806  36.624  1.00 40.71  ? 151 ARG B CZ  1 
ATOM   4702  N NH1 . ARG B 1 151 ? 12.725  48.429  37.287  1.00 36.97  ? 151 ARG B NH1 1 
ATOM   4703  N NH2 . ARG B 1 151 ? 14.945  47.809  37.063  1.00 45.07  ? 151 ARG B NH2 1 
ATOM   4704  N N   . GLU B 1 152 ? 7.564   45.737  35.814  1.00 30.23  ? 152 GLU B N   1 
ATOM   4705  C CA  . GLU B 1 152 ? 7.001   45.888  37.160  1.00 30.28  ? 152 GLU B CA  1 
ATOM   4706  C C   . GLU B 1 152 ? 5.973   44.803  37.515  1.00 25.20  ? 152 GLU B C   1 
ATOM   4707  O O   . GLU B 1 152 ? 5.442   44.821  38.619  1.00 25.18  ? 152 GLU B O   1 
ATOM   4708  C CB  . GLU B 1 152 ? 6.385   47.272  37.407  1.00 29.41  ? 152 GLU B CB  1 
ATOM   4709  C CG  . GLU B 1 152 ? 7.343   48.434  37.142  1.00 30.67  ? 152 GLU B CG  1 
ATOM   4710  C CD  . GLU B 1 152 ? 8.784   48.266  37.609  1.00 31.06  ? 152 GLU B CD  1 
ATOM   4711  O OE1 . GLU B 1 152 ? 9.663   48.365  36.722  1.00 30.22  ? 152 GLU B OE1 1 
ATOM   4712  O OE2 . GLU B 1 152 ? 9.037   48.042  38.827  1.00 31.60  ? 152 GLU B OE2 1 
ATOM   4713  N N   . SER B 1 153 ? 5.769   43.810  36.641  1.00 24.65  ? 153 SER B N   1 
ATOM   4714  C CA  . SER B 1 153 ? 4.796   42.748  36.889  1.00 28.69  ? 153 SER B CA  1 
ATOM   4715  C C   . SER B 1 153 ? 5.093   41.996  38.185  1.00 29.84  ? 153 SER B C   1 
ATOM   4716  O O   . SER B 1 153 ? 6.099   41.292  38.287  1.00 28.34  ? 153 SER B O   1 
ATOM   4717  C CB  . SER B 1 153 ? 4.722   41.759  35.734  1.00 26.81  ? 153 SER B CB  1 
ATOM   4718  O OG  . SER B 1 153 ? 3.760   40.747  36.005  1.00 25.88  ? 153 SER B OG  1 
ATOM   4719  N N   . VAL B 1 154 ? 4.162   42.080  39.131  1.00 30.77  ? 154 VAL B N   1 
ATOM   4720  C CA  . VAL B 1 154 ? 4.187   41.207  40.297  1.00 34.59  ? 154 VAL B CA  1 
ATOM   4721  C C   . VAL B 1 154 ? 3.865   39.757  39.903  1.00 33.08  ? 154 VAL B C   1 
ATOM   4722  O O   . VAL B 1 154 ? 4.465   38.818  40.408  1.00 30.63  ? 154 VAL B O   1 
ATOM   4723  C CB  . VAL B 1 154 ? 3.200   41.737  41.351  1.00 36.74  ? 154 VAL B CB  1 
ATOM   4724  C CG1 . VAL B 1 154 ? 3.071   40.803  42.561  1.00 38.62  ? 154 VAL B CG1 1 
ATOM   4725  C CG2 . VAL B 1 154 ? 3.571   43.147  41.773  1.00 35.97  ? 154 VAL B CG2 1 
ATOM   4726  N N   . PHE B 1 155 ? 2.881   39.551  39.032  1.00 31.17  ? 155 PHE B N   1 
ATOM   4727  C CA  . PHE B 1 155 ? 2.573   38.196  38.611  1.00 31.93  ? 155 PHE B CA  1 
ATOM   4728  C C   . PHE B 1 155 ? 3.852   37.547  38.100  1.00 32.33  ? 155 PHE B C   1 
ATOM   4729  O O   . PHE B 1 155 ? 4.198   36.476  38.578  1.00 32.69  ? 155 PHE B O   1 
ATOM   4730  C CB  . PHE B 1 155 ? 1.426   38.144  37.592  1.00 30.12  ? 155 PHE B CB  1 
ATOM   4731  C CG  . PHE B 1 155 ? 1.046   36.745  37.133  1.00 33.67  ? 155 PHE B CG  1 
ATOM   4732  C CD1 . PHE B 1 155 ? 1.764   36.086  36.136  1.00 37.79  ? 155 PHE B CD1 1 
ATOM   4733  C CD2 . PHE B 1 155 ? -0.044  36.086  37.684  1.00 39.59  ? 155 PHE B CD2 1 
ATOM   4734  C CE1 . PHE B 1 155 ? 1.401   34.817  35.706  1.00 40.29  ? 155 PHE B CE1 1 
ATOM   4735  C CE2 . PHE B 1 155 ? -0.403  34.807  37.250  1.00 40.84  ? 155 PHE B CE2 1 
ATOM   4736  C CZ  . PHE B 1 155 ? 0.316   34.174  36.267  1.00 41.49  ? 155 PHE B CZ  1 
ATOM   4737  N N   . ALA B 1 156 ? 4.551   38.204  37.154  1.00 32.83  ? 156 ALA B N   1 
ATOM   4738  C CA  . ALA B 1 156 ? 5.691   37.604  36.458  1.00 34.85  ? 156 ALA B CA  1 
ATOM   4739  C C   . ALA B 1 156 ? 6.823   37.271  37.429  1.00 31.52  ? 156 ALA B C   1 
ATOM   4740  O O   . ALA B 1 156 ? 7.425   36.210  37.333  1.00 29.73  ? 156 ALA B O   1 
ATOM   4741  C CB  . ALA B 1 156 ? 6.196   38.512  35.328  1.00 33.11  ? 156 ALA B CB  1 
ATOM   4742  N N   . LYS B 1 157 ? 7.111   38.211  38.331  1.00 32.93  ? 157 LYS B N   1 
ATOM   4743  C CA  . LYS B 1 157 ? 8.046   38.013  39.424  1.00 39.06  ? 157 LYS B CA  1 
ATOM   4744  C C   . LYS B 1 157 ? 7.641   36.822  40.294  1.00 43.61  ? 157 LYS B C   1 
ATOM   4745  O O   . LYS B 1 157 ? 8.432   35.905  40.516  1.00 44.35  ? 157 LYS B O   1 
ATOM   4746  C CB  . LYS B 1 157 ? 8.064   39.290  40.265  1.00 43.24  ? 157 LYS B CB  1 
ATOM   4747  C CG  . LYS B 1 157 ? 9.221   39.381  41.224  1.00 51.05  ? 157 LYS B CG  1 
ATOM   4748  C CD  . LYS B 1 157 ? 9.108   40.523  42.231  1.00 59.09  ? 157 LYS B CD  1 
ATOM   4749  C CE  . LYS B 1 157 ? 10.316  40.586  43.132  1.00 59.16  ? 157 LYS B CE  1 
ATOM   4750  N NZ  . LYS B 1 157 ? 9.940   41.202  44.400  1.00 63.48  ? 157 LYS B NZ  1 
ATOM   4751  N N   . ARG B 1 158 ? 6.394   36.824  40.781  1.00 48.36  ? 158 ARG B N   1 
ATOM   4752  C CA  . ARG B 1 158 ? 5.953   35.795  41.709  1.00 49.07  ? 158 ARG B CA  1 
ATOM   4753  C C   . ARG B 1 158 ? 5.979   34.436  41.013  1.00 42.52  ? 158 ARG B C   1 
ATOM   4754  O O   . ARG B 1 158 ? 6.287   33.436  41.648  1.00 43.23  ? 158 ARG B O   1 
ATOM   4755  C CB  . ARG B 1 158 ? 4.640   36.119  42.442  1.00 58.00  ? 158 ARG B CB  1 
ATOM   4756  C CG  . ARG B 1 158 ? 4.854   36.789  43.800  1.00 67.80  ? 158 ARG B CG  1 
ATOM   4757  C CD  . ARG B 1 158 ? 3.745   36.505  44.817  1.00 84.75  ? 158 ARG B CD  1 
ATOM   4758  N NE  . ARG B 1 158 ? 2.679   37.521  44.841  1.00 96.79  ? 158 ARG B NE  1 
ATOM   4759  C CZ  . ARG B 1 158 ? 1.442   37.358  45.336  1.00 92.33  ? 158 ARG B CZ  1 
ATOM   4760  N NH1 . ARG B 1 158 ? 0.622   38.406  45.412  1.00 74.52  ? 158 ARG B NH1 1 
ATOM   4761  N NH2 . ARG B 1 158 ? 1.040   36.162  45.764  1.00 88.26  ? 158 ARG B NH2 1 
ATOM   4762  N N   . TYR B 1 159 ? 5.733   34.386  39.710  1.00 37.27  ? 159 TYR B N   1 
ATOM   4763  C CA  . TYR B 1 159 ? 5.738   33.099  39.031  1.00 40.01  ? 159 TYR B CA  1 
ATOM   4764  C C   . TYR B 1 159 ? 7.166   32.548  39.003  1.00 44.43  ? 159 TYR B C   1 
ATOM   4765  O O   . TYR B 1 159 ? 7.377   31.353  39.216  1.00 43.51  ? 159 TYR B O   1 
ATOM   4766  C CB  . TYR B 1 159 ? 5.147   33.183  37.621  1.00 38.33  ? 159 TYR B CB  1 
ATOM   4767  C CG  . TYR B 1 159 ? 4.974   31.822  36.970  1.00 38.52  ? 159 TYR B CG  1 
ATOM   4768  C CD1 . TYR B 1 159 ? 3.808   31.084  37.133  1.00 40.79  ? 159 TYR B CD1 1 
ATOM   4769  C CD2 . TYR B 1 159 ? 5.989   31.265  36.204  1.00 38.04  ? 159 TYR B CD2 1 
ATOM   4770  C CE1 . TYR B 1 159 ? 3.648   29.844  36.535  1.00 36.61  ? 159 TYR B CE1 1 
ATOM   4771  C CE2 . TYR B 1 159 ? 5.856   30.010  35.638  1.00 36.94  ? 159 TYR B CE2 1 
ATOM   4772  C CZ  . TYR B 1 159 ? 4.677   29.309  35.796  1.00 35.62  ? 159 TYR B CZ  1 
ATOM   4773  O OH  . TYR B 1 159 ? 4.550   28.092  35.208  1.00 40.58  ? 159 TYR B OH  1 
ATOM   4774  N N   . GLU B 1 160 ? 8.147   33.422  38.746  1.00 47.25  ? 160 GLU B N   1 
ATOM   4775  C CA  . GLU B 1 160 ? 9.526   32.975  38.619  1.00 49.89  ? 160 GLU B CA  1 
ATOM   4776  C C   . GLU B 1 160 ? 9.974   32.402  39.968  1.00 46.16  ? 160 GLU B C   1 
ATOM   4777  O O   . GLU B 1 160 ? 10.548  31.316  39.984  1.00 40.91  ? 160 GLU B O   1 
ATOM   4778  C CB  . GLU B 1 160 ? 10.459  34.060  38.070  1.00 53.30  ? 160 GLU B CB  1 
ATOM   4779  C CG  . GLU B 1 160 ? 11.326  33.582  36.902  1.00 68.63  ? 160 GLU B CG  1 
ATOM   4780  C CD  . GLU B 1 160 ? 10.709  33.516  35.487  1.00 82.09  ? 160 GLU B CD  1 
ATOM   4781  O OE1 . GLU B 1 160 ? 9.729   32.747  35.252  1.00 71.85  ? 160 GLU B OE1 1 
ATOM   4782  O OE2 . GLU B 1 160 ? 11.231  34.236  34.579  1.00 75.64  ? 160 GLU B OE2 1 
ATOM   4783  N N   . GLU B 1 161 ? 9.664   33.107  41.076  1.00 39.58  ? 161 GLU B N   1 
ATOM   4784  C CA  . GLU B 1 161 ? 10.009  32.671  42.427  1.00 42.11  ? 161 GLU B CA  1 
ATOM   4785  C C   . GLU B 1 161 ? 9.342   31.338  42.783  1.00 44.64  ? 161 GLU B C   1 
ATOM   4786  O O   . GLU B 1 161 ? 9.961   30.462  43.377  1.00 49.92  ? 161 GLU B O   1 
ATOM   4787  C CB  . GLU B 1 161 ? 9.608   33.692  43.487  1.00 41.34  ? 161 GLU B CB  1 
ATOM   4788  C CG  . GLU B 1 161 ? 10.351  35.013  43.315  1.00 50.28  ? 161 GLU B CG  1 
ATOM   4789  C CD  . GLU B 1 161 ? 9.878   36.204  44.128  1.00 55.02  ? 161 GLU B CD  1 
ATOM   4790  O OE1 . GLU B 1 161 ? 10.650  37.186  44.116  1.00 55.74  ? 161 GLU B OE1 1 
ATOM   4791  O OE2 . GLU B 1 161 ? 8.783   36.170  44.738  1.00 56.46  ? 161 GLU B OE2 1 
ATOM   4792  N N   . GLY B 1 162 ? 8.093   31.165  42.361  1.00 44.31  ? 162 GLY B N   1 
ATOM   4793  C CA  . GLY B 1 162 ? 7.315   29.985  42.681  1.00 42.13  ? 162 GLY B CA  1 
ATOM   4794  C C   . GLY B 1 162 ? 6.026   30.424  43.358  1.00 43.14  ? 162 GLY B C   1 
ATOM   4795  O O   . GLY B 1 162 ? 6.058   31.164  44.336  1.00 42.73  ? 162 GLY B O   1 
ATOM   4796  N N   . MET B 1 163 ? 4.896   30.081  42.746  1.00 45.89  ? 163 MET B N   1 
ATOM   4797  C CA  . MET B 1 163 ? 3.606   30.371  43.349  1.00 45.45  ? 163 MET B CA  1 
ATOM   4798  C C   . MET B 1 163 ? 2.583   29.330  42.884  1.00 50.77  ? 163 MET B C   1 
ATOM   4799  O O   . MET B 1 163 ? 2.584   28.869  41.729  1.00 42.37  ? 163 MET B O   1 
ATOM   4800  C CB  . MET B 1 163 ? 3.166   31.819  43.083  1.00 39.39  ? 163 MET B CB  1 
ATOM   4801  C CG  . MET B 1 163 ? 2.602   32.114  41.699  1.00 37.42  ? 163 MET B CG  1 
ATOM   4802  S SD  . MET B 1 163 ? 1.735   33.703  41.693  1.00 40.69  ? 163 MET B SD  1 
ATOM   4803  C CE  . MET B 1 163 ? 1.997   34.056  39.948  1.00 41.15  ? 163 MET B CE  1 
ATOM   4804  N N   . ARG B 1 164 ? 1.729   28.941  43.838  1.00 57.82  ? 164 ARG B N   1 
ATOM   4805  C CA  . ARG B 1 164 ? 0.635   28.026  43.573  1.00 70.43  ? 164 ARG B CA  1 
ATOM   4806  C C   . ARG B 1 164 ? -0.389  28.746  42.699  1.00 57.71  ? 164 ARG B C   1 
ATOM   4807  O O   . ARG B 1 164 ? -0.551  29.959  42.797  1.00 52.92  ? 164 ARG B O   1 
ATOM   4808  C CB  . ARG B 1 164 ? 0.075   27.568  44.927  1.00 89.78  ? 164 ARG B CB  1 
ATOM   4809  C CG  . ARG B 1 164 ? 1.007   26.738  45.801  1.00 97.88  ? 164 ARG B CG  1 
ATOM   4810  C CD  . ARG B 1 164 ? 0.868   27.079  47.292  1.00 109.84 ? 164 ARG B CD  1 
ATOM   4811  N NE  . ARG B 1 164 ? -0.494  26.994  47.840  1.00 122.98 ? 164 ARG B NE  1 
ATOM   4812  C CZ  . ARG B 1 164 ? -1.218  25.881  48.011  1.00 126.53 ? 164 ARG B CZ  1 
ATOM   4813  N NH1 . ARG B 1 164 ? -0.725  24.699  47.675  1.00 131.70 ? 164 ARG B NH1 1 
ATOM   4814  N NH2 . ARG B 1 164 ? -2.440  25.953  48.516  1.00 114.43 ? 164 ARG B NH2 1 
ATOM   4815  N N   . ARG B 1 165 ? -1.099  27.982  41.867  1.00 55.49  ? 165 ARG B N   1 
ATOM   4816  C CA  . ARG B 1 165 ? -2.134  28.528  40.997  1.00 58.63  ? 165 ARG B CA  1 
ATOM   4817  C C   . ARG B 1 165 ? -3.164  29.364  41.773  1.00 50.68  ? 165 ARG B C   1 
ATOM   4818  O O   . ARG B 1 165 ? -3.774  30.260  41.198  1.00 47.19  ? 165 ARG B O   1 
ATOM   4819  C CB  . ARG B 1 165 ? -2.713  27.378  40.158  1.00 66.49  ? 165 ARG B CB  1 
ATOM   4820  C CG  . ARG B 1 165 ? -1.839  27.039  38.955  1.00 79.45  ? 165 ARG B CG  1 
ATOM   4821  C CD  . ARG B 1 165 ? -1.667  25.558  38.641  1.00 90.67  ? 165 ARG B CD  1 
ATOM   4822  N NE  . ARG B 1 165 ? -2.934  24.850  38.425  1.00 90.42  ? 165 ARG B NE  1 
ATOM   4823  C CZ  . ARG B 1 165 ? -3.367  23.865  39.211  1.00 103.63 ? 165 ARG B CZ  1 
ATOM   4824  N NH1 . ARG B 1 165 ? -2.651  23.446  40.248  1.00 95.68  ? 165 ARG B NH1 1 
ATOM   4825  N NH2 . ARG B 1 165 ? -4.532  23.298  38.965  1.00 108.96 ? 165 ARG B NH2 1 
ATOM   4826  N N   . GLU B 1 166 ? -3.332  29.098  43.077  1.00 50.08  ? 166 GLU B N   1 
ATOM   4827  C CA  . GLU B 1 166 ? -4.323  29.760  43.913  1.00 52.71  ? 166 GLU B CA  1 
ATOM   4828  C C   . GLU B 1 166 ? -4.014  31.241  44.126  1.00 51.66  ? 166 GLU B C   1 
ATOM   4829  O O   . GLU B 1 166 ? -4.920  32.003  44.450  1.00 53.22  ? 166 GLU B O   1 
ATOM   4830  C CB  . GLU B 1 166 ? -4.405  29.144  45.313  1.00 66.05  ? 166 GLU B CB  1 
ATOM   4831  C CG  . GLU B 1 166 ? -5.055  27.762  45.336  1.00 76.09  ? 166 GLU B CG  1 
ATOM   4832  C CD  . GLU B 1 166 ? -4.218  26.629  44.763  1.00 85.56  ? 166 GLU B CD  1 
ATOM   4833  O OE1 . GLU B 1 166 ? -4.781  25.526  44.635  1.00 102.09 ? 166 GLU B OE1 1 
ATOM   4834  O OE2 . GLU B 1 166 ? -3.025  26.821  44.442  1.00 81.39  ? 166 GLU B OE2 1 
ATOM   4835  N N   . GLU B 1 167 ? -2.740  31.644  44.028  1.00 47.99  ? 167 GLU B N   1 
ATOM   4836  C CA  . GLU B 1 167 ? -2.396  33.037  44.266  1.00 49.63  ? 167 GLU B CA  1 
ATOM   4837  C C   . GLU B 1 167 ? -2.420  33.833  42.964  1.00 42.71  ? 167 GLU B C   1 
ATOM   4838  O O   . GLU B 1 167 ? -2.290  35.064  43.018  1.00 41.03  ? 167 GLU B O   1 
ATOM   4839  C CB  . GLU B 1 167 ? -0.980  33.285  44.780  1.00 61.77  ? 167 GLU B CB  1 
ATOM   4840  C CG  . GLU B 1 167 ? -0.585  32.561  46.061  1.00 71.57  ? 167 GLU B CG  1 
ATOM   4841  C CD  . GLU B 1 167 ? 0.936   32.439  46.065  1.00 83.34  ? 167 GLU B CD  1 
ATOM   4842  O OE1 . GLU B 1 167 ? 1.646   33.486  45.837  1.00 67.80  ? 167 GLU B OE1 1 
ATOM   4843  O OE2 . GLU B 1 167 ? 1.385   31.262  46.237  1.00 75.17  ? 167 GLU B OE2 1 
ATOM   4844  N N   . HIS B 1 168 ? -2.530  33.125  41.817  1.00 36.43  ? 168 HIS B N   1 
ATOM   4845  C CA  . HIS B 1 168 ? -2.524  33.752  40.502  1.00 32.91  ? 168 HIS B CA  1 
ATOM   4846  C C   . HIS B 1 168 ? -3.396  35.003  40.516  1.00 36.21  ? 168 HIS B C   1 
ATOM   4847  O O   . HIS B 1 168 ? -2.913  36.065  40.138  1.00 38.48  ? 168 HIS B O   1 
ATOM   4848  C CB  . HIS B 1 168 ? -2.979  32.808  39.392  1.00 32.90  ? 168 HIS B CB  1 
ATOM   4849  C CG  . HIS B 1 168 ? -1.934  31.862  38.929  1.00 37.00  ? 168 HIS B CG  1 
ATOM   4850  N ND1 . HIS B 1 168 ? -2.072  31.178  37.741  1.00 39.28  ? 168 HIS B ND1 1 
ATOM   4851  C CD2 . HIS B 1 168 ? -0.752  31.469  39.456  1.00 37.81  ? 168 HIS B CD2 1 
ATOM   4852  C CE1 . HIS B 1 168 ? -1.004  30.402  37.561  1.00 41.57  ? 168 HIS B CE1 1 
ATOM   4853  N NE2 . HIS B 1 168 ? -0.188  30.566  38.587  1.00 39.89  ? 168 HIS B NE2 1 
ATOM   4854  N N   . TRP B 1 169 ? -4.650  34.882  40.996  1.00 35.77  ? 169 TRP B N   1 
ATOM   4855  C CA  . TRP B 1 169 ? -5.599  35.989  40.973  1.00 34.87  ? 169 TRP B CA  1 
ATOM   4856  C C   . TRP B 1 169 ? -5.148  37.175  41.839  1.00 35.24  ? 169 TRP B C   1 
ATOM   4857  O O   . TRP B 1 169 ? -5.425  38.330  41.502  1.00 33.03  ? 169 TRP B O   1 
ATOM   4858  C CB  . TRP B 1 169 ? -7.005  35.496  41.358  1.00 34.25  ? 169 TRP B CB  1 
ATOM   4859  C CG  . TRP B 1 169 ? -7.199  35.172  42.811  1.00 32.85  ? 169 TRP B CG  1 
ATOM   4860  C CD1 . TRP B 1 169 ? -7.114  33.953  43.427  1.00 37.38  ? 169 TRP B CD1 1 
ATOM   4861  C CD2 . TRP B 1 169 ? -7.550  36.115  43.836  1.00 31.14  ? 169 TRP B CD2 1 
ATOM   4862  N NE1 . TRP B 1 169 ? -7.363  34.073  44.772  1.00 35.75  ? 169 TRP B NE1 1 
ATOM   4863  C CE2 . TRP B 1 169 ? -7.640  35.388  45.052  1.00 34.38  ? 169 TRP B CE2 1 
ATOM   4864  C CE3 . TRP B 1 169 ? -7.785  37.494  43.836  1.00 31.84  ? 169 TRP B CE3 1 
ATOM   4865  C CZ2 . TRP B 1 169 ? -7.963  35.998  46.263  1.00 34.50  ? 169 TRP B CZ2 1 
ATOM   4866  C CZ3 . TRP B 1 169 ? -8.126  38.096  45.029  1.00 34.96  ? 169 TRP B CZ3 1 
ATOM   4867  C CH2 . TRP B 1 169 ? -8.204  37.356  46.227  1.00 37.19  ? 169 TRP B CH2 1 
ATOM   4868  N N   . GLU B 1 170 ? -4.448  36.892  42.946  1.00 35.14  ? 170 GLU B N   1 
ATOM   4869  C CA  . GLU B 1 170 ? -3.978  37.932  43.856  1.00 38.15  ? 170 GLU B CA  1 
ATOM   4870  C C   . GLU B 1 170 ? -2.986  38.840  43.138  1.00 35.91  ? 170 GLU B C   1 
ATOM   4871  O O   . GLU B 1 170 ? -3.156  40.052  43.172  1.00 39.34  ? 170 GLU B O   1 
ATOM   4872  C CB  . GLU B 1 170 ? -3.356  37.332  45.121  1.00 40.65  ? 170 GLU B CB  1 
ATOM   4873  C CG  . GLU B 1 170 ? -4.323  36.412  45.868  1.00 42.49  ? 170 GLU B CG  1 
ATOM   4874  C CD  . GLU B 1 170 ? -4.003  36.146  47.328  1.00 43.69  ? 170 GLU B CD  1 
ATOM   4875  O OE1 . GLU B 1 170 ? -4.091  34.969  47.683  1.00 45.16  ? 170 GLU B OE1 1 
ATOM   4876  O OE2 . GLU B 1 170 ? -3.673  37.072  48.098  1.00 42.07  ? 170 GLU B OE2 1 
ATOM   4877  N N   . ALA B 1 171 ? -1.983  38.226  42.484  1.00 31.59  ? 171 ALA B N   1 
ATOM   4878  C CA  . ALA B 1 171 ? -0.986  38.907  41.659  1.00 32.71  ? 171 ALA B CA  1 
ATOM   4879  C C   . ALA B 1 171 ? -1.632  39.620  40.467  1.00 31.12  ? 171 ALA B C   1 
ATOM   4880  O O   . ALA B 1 171 ? -1.280  40.750  40.116  1.00 27.04  ? 171 ALA B O   1 
ATOM   4881  C CB  . ALA B 1 171 ? 0.068   37.914  41.168  1.00 31.66  ? 171 ALA B CB  1 
ATOM   4882  N N   . MET B 1 172 ? -2.579  38.938  39.832  1.00 30.31  ? 172 MET B N   1 
ATOM   4883  C CA  . MET B 1 172 ? -3.296  39.536  38.741  1.00 31.55  ? 172 MET B CA  1 
ATOM   4884  C C   . MET B 1 172 ? -3.960  40.826  39.219  1.00 33.12  ? 172 MET B C   1 
ATOM   4885  O O   . MET B 1 172 ? -3.966  41.825  38.501  1.00 40.08  ? 172 MET B O   1 
ATOM   4886  C CB  . MET B 1 172 ? -4.264  38.506  38.192  1.00 33.93  ? 172 MET B CB  1 
ATOM   4887  C CG  . MET B 1 172 ? -3.572  37.549  37.278  1.00 36.19  ? 172 MET B CG  1 
ATOM   4888  S SD  . MET B 1 172 ? -3.185  38.406  35.741  1.00 39.05  ? 172 MET B SD  1 
ATOM   4889  C CE  . MET B 1 172 ? -2.292  37.011  35.074  1.00 42.11  ? 172 MET B CE  1 
ATOM   4890  N N   . LEU B 1 173 ? -4.459  40.828  40.450  1.00 29.01  ? 173 LEU B N   1 
ATOM   4891  C CA  . LEU B 1 173 ? -5.192  41.988  40.938  1.00 30.45  ? 173 LEU B CA  1 
ATOM   4892  C C   . LEU B 1 173 ? -4.208  43.103  41.283  1.00 29.26  ? 173 LEU B C   1 
ATOM   4893  O O   . LEU B 1 173 ? -4.489  44.278  41.064  1.00 28.14  ? 173 LEU B O   1 
ATOM   4894  C CB  . LEU B 1 173 ? -6.072  41.578  42.121  1.00 28.21  ? 173 LEU B CB  1 
ATOM   4895  C CG  . LEU B 1 173 ? -6.753  42.704  42.902  1.00 30.64  ? 173 LEU B CG  1 
ATOM   4896  C CD1 . LEU B 1 173 ? -7.923  43.289  42.129  1.00 30.43  ? 173 LEU B CD1 1 
ATOM   4897  C CD2 . LEU B 1 173 ? -7.191  42.213  44.292  1.00 30.61  ? 173 LEU B CD2 1 
ATOM   4898  N N   . GLU B 1 174 ? -3.068  42.723  41.861  1.00 28.59  ? 174 GLU B N   1 
ATOM   4899  C CA  . GLU B 1 174 ? -2.058  43.694  42.225  1.00 29.54  ? 174 GLU B CA  1 
ATOM   4900  C C   . GLU B 1 174 ? -1.635  44.428  40.956  1.00 25.93  ? 174 GLU B C   1 
ATOM   4901  O O   . GLU B 1 174 ? -1.632  45.650  40.915  1.00 25.53  ? 174 GLU B O   1 
ATOM   4902  C CB  . GLU B 1 174 ? -0.926  42.999  42.992  1.00 31.68  ? 174 GLU B CB  1 
ATOM   4903  C CG  . GLU B 1 174 ? 0.132   43.946  43.568  1.00 33.96  ? 174 GLU B CG  1 
ATOM   4904  C CD  . GLU B 1 174 ? -0.325  44.981  44.597  1.00 35.66  ? 174 GLU B CD  1 
ATOM   4905  O OE1 . GLU B 1 174 ? -1.395  44.804  45.216  1.00 33.36  ? 174 GLU B OE1 1 
ATOM   4906  O OE2 . GLU B 1 174 ? 0.381   46.008  44.754  1.00 36.34  ? 174 GLU B OE2 1 
ATOM   4907  N N   . ASP B 1 175 ? -1.334  43.659  39.909  1.00 28.36  ? 175 ASP B N   1 
ATOM   4908  C CA  . ASP B 1 175 ? -0.879  44.186  38.619  1.00 27.35  ? 175 ASP B CA  1 
ATOM   4909  C C   . ASP B 1 175 ? -1.943  45.055  37.952  1.00 25.93  ? 175 ASP B C   1 
ATOM   4910  O O   . ASP B 1 175 ? -1.617  46.106  37.393  1.00 23.67  ? 175 ASP B O   1 
ATOM   4911  C CB  . ASP B 1 175 ? -0.416  43.079  37.680  1.00 27.09  ? 175 ASP B CB  1 
ATOM   4912  C CG  . ASP B 1 175 ? 1.010   42.587  37.880  1.00 27.75  ? 175 ASP B CG  1 
ATOM   4913  O OD1 . ASP B 1 175 ? 1.771   43.264  38.594  1.00 30.17  ? 175 ASP B OD1 1 
ATOM   4914  O OD2 . ASP B 1 175 ? 1.358   41.529  37.311  1.00 30.03  ? 175 ASP B OD2 1 
ATOM   4915  N N   . SER B 1 176 ? -3.203  44.601  38.029  1.00 27.09  ? 176 SER B N   1 
ATOM   4916  C CA  . SER B 1 176 ? -4.344  45.324  37.487  1.00 26.17  ? 176 SER B CA  1 
ATOM   4917  C C   . SER B 1 176 ? -4.499  46.692  38.167  1.00 28.11  ? 176 SER B C   1 
ATOM   4918  O O   . SER B 1 176 ? -4.718  47.712  37.503  1.00 26.87  ? 176 SER B O   1 
ATOM   4919  C CB  . SER B 1 176 ? -5.577  44.480  37.591  1.00 25.06  ? 176 SER B CB  1 
ATOM   4920  O OG  . SER B 1 176 ? -5.482  43.305  36.794  1.00 23.08  ? 176 SER B OG  1 
ATOM   4921  N N   . LEU B 1 177 ? -4.312  46.758  39.488  1.00 27.74  ? 177 LEU B N   1 
ATOM   4922  C CA  . LEU B 1 177 ? -4.441  48.048  40.161  1.00 28.49  ? 177 LEU B CA  1 
ATOM   4923  C C   . LEU B 1 177 ? -3.357  48.984  39.619  1.00 28.37  ? 177 LEU B C   1 
ATOM   4924  O O   . LEU B 1 177 ? -3.623  50.132  39.278  1.00 28.66  ? 177 LEU B O   1 
ATOM   4925  C CB  . LEU B 1 177 ? -4.360  47.915  41.682  1.00 29.77  ? 177 LEU B CB  1 
ATOM   4926  C CG  . LEU B 1 177 ? -5.526  47.215  42.388  1.00 31.29  ? 177 LEU B CG  1 
ATOM   4927  C CD1 . LEU B 1 177 ? -5.202  46.858  43.838  1.00 30.83  ? 177 LEU B CD1 1 
ATOM   4928  C CD2 . LEU B 1 177 ? -6.753  48.114  42.354  1.00 33.22  ? 177 LEU B CD2 1 
ATOM   4929  N N   . ASN B 1 178 ? -2.131  48.461  39.484  1.00 28.87  ? 178 ASN B N   1 
ATOM   4930  C CA  . ASN B 1 178 ? -0.994  49.239  39.005  1.00 27.09  ? 178 ASN B CA  1 
ATOM   4931  C C   . ASN B 1 178 ? -1.188  49.769  37.574  1.00 27.04  ? 178 ASN B C   1 
ATOM   4932  O O   . ASN B 1 178 ? -1.077  50.999  37.344  1.00 25.74  ? 178 ASN B O   1 
ATOM   4933  C CB  . ASN B 1 178 ? 0.263   48.398  39.141  1.00 25.93  ? 178 ASN B CB  1 
ATOM   4934  C CG  . ASN B 1 178 ? 0.733   48.356  40.575  1.00 26.04  ? 178 ASN B CG  1 
ATOM   4935  O OD1 . ASN B 1 178 ? 0.410   49.235  41.380  1.00 24.14  ? 178 ASN B OD1 1 
ATOM   4936  N ND2 . ASN B 1 178 ? 1.591   47.402  40.877  1.00 26.66  ? 178 ASN B ND2 1 
ATOM   4937  N N   . MET B 1 179 ? -1.485  48.835  36.640  1.00 22.53  ? 179 MET B N   1 
ATOM   4938  C CA  . MET B 1 179 ? -1.645  49.164  35.229  1.00 25.01  ? 179 MET B CA  1 
ATOM   4939  C C   . MET B 1 179 ? -2.829  50.117  35.039  1.00 25.38  ? 179 MET B C   1 
ATOM   4940  O O   . MET B 1 179 ? -2.668  51.141  34.391  1.00 23.05  ? 179 MET B O   1 
ATOM   4941  C CB  . MET B 1 179 ? -1.813  47.922  34.344  1.00 26.22  ? 179 MET B CB  1 
ATOM   4942  C CG  . MET B 1 179 ? -1.923  48.216  32.850  1.00 25.20  ? 179 MET B CG  1 
ATOM   4943  S SD  . MET B 1 179 ? -2.243  46.692  31.932  1.00 25.87  ? 179 MET B SD  1 
ATOM   4944  C CE  . MET B 1 179 ? -4.033  46.640  32.151  1.00 26.11  ? 179 MET B CE  1 
ATOM   4945  N N   . LEU B 1 180 ? -3.996  49.830  35.641  1.00 26.96  ? 180 LEU B N   1 
ATOM   4946  C CA  . LEU B 1 180 ? -5.151  50.701  35.459  1.00 27.98  ? 180 LEU B CA  1 
ATOM   4947  C C   . LEU B 1 180 ? -4.784  52.123  35.907  1.00 28.12  ? 180 LEU B C   1 
ATOM   4948  O O   . LEU B 1 180 ? -5.088  53.124  35.220  1.00 25.58  ? 180 LEU B O   1 
ATOM   4949  C CB  . LEU B 1 180 ? -6.392  50.173  36.186  1.00 29.94  ? 180 LEU B CB  1 
ATOM   4950  C CG  . LEU B 1 180 ? -7.109  48.981  35.551  1.00 30.49  ? 180 LEU B CG  1 
ATOM   4951  C CD1 . LEU B 1 180 ? -8.153  48.482  36.523  1.00 34.39  ? 180 LEU B CD1 1 
ATOM   4952  C CD2 . LEU B 1 180 ? -7.766  49.321  34.220  1.00 30.57  ? 180 LEU B CD2 1 
ATOM   4953  N N   . ALA B 1 181 ? -4.115  52.213  37.060  1.00 25.01  ? 181 ALA B N   1 
ATOM   4954  C CA  . ALA B 1 181 ? -3.722  53.511  37.574  1.00 28.12  ? 181 ALA B CA  1 
ATOM   4955  C C   . ALA B 1 181 ? -2.855  54.249  36.551  1.00 32.39  ? 181 ALA B C   1 
ATOM   4956  O O   . ALA B 1 181 ? -2.909  55.475  36.467  1.00 34.89  ? 181 ALA B O   1 
ATOM   4957  C CB  . ALA B 1 181 ? -2.986  53.327  38.869  1.00 27.88  ? 181 ALA B CB  1 
ATOM   4958  N N   . ALA B 1 182 ? -2.061  53.474  35.799  1.00 29.38  ? 182 ALA B N   1 
ATOM   4959  C CA  . ALA B 1 182 ? -1.090  53.986  34.853  1.00 30.48  ? 182 ALA B CA  1 
ATOM   4960  C C   . ALA B 1 182 ? -1.764  54.487  33.578  1.00 32.35  ? 182 ALA B C   1 
ATOM   4961  O O   . ALA B 1 182 ? -1.364  55.511  33.022  1.00 31.79  ? 182 ALA B O   1 
ATOM   4962  C CB  . ALA B 1 182 ? -0.099  52.875  34.538  1.00 30.93  ? 182 ALA B CB  1 
ATOM   4963  N N   . LEU B 1 183 ? -2.798  53.770  33.118  1.00 31.01  ? 183 LEU B N   1 
ATOM   4964  C CA  . LEU B 1 183 ? -3.313  53.989  31.781  1.00 28.54  ? 183 LEU B CA  1 
ATOM   4965  C C   . LEU B 1 183 ? -3.672  55.470  31.604  1.00 27.16  ? 183 LEU B C   1 
ATOM   4966  O O   . LEU B 1 183 ? -3.367  56.029  30.558  1.00 26.08  ? 183 LEU B O   1 
ATOM   4967  C CB  . LEU B 1 183 ? -4.478  53.059  31.435  1.00 29.58  ? 183 LEU B CB  1 
ATOM   4968  C CG  . LEU B 1 183 ? -4.225  51.544  31.498  1.00 30.02  ? 183 LEU B CG  1 
ATOM   4969  C CD1 . LEU B 1 183 ? -5.462  50.818  30.955  1.00 31.31  ? 183 LEU B CD1 1 
ATOM   4970  C CD2 . LEU B 1 183 ? -2.980  51.015  30.787  1.00 30.27  ? 183 LEU B CD2 1 
ATOM   4971  N N   . PRO B 1 184 ? -4.343  56.166  32.558  1.00 26.03  ? 184 PRO B N   1 
ATOM   4972  C CA  . PRO B 1 184 ? -4.672  57.586  32.377  1.00 25.79  ? 184 PRO B CA  1 
ATOM   4973  C C   . PRO B 1 184 ? -3.443  58.473  32.193  1.00 25.92  ? 184 PRO B C   1 
ATOM   4974  O O   . PRO B 1 184 ? -3.445  59.424  31.417  1.00 28.97  ? 184 PRO B O   1 
ATOM   4975  C CB  . PRO B 1 184 ? -5.427  57.911  33.676  1.00 26.29  ? 184 PRO B CB  1 
ATOM   4976  C CG  . PRO B 1 184 ? -6.011  56.592  34.121  1.00 24.32  ? 184 PRO B CG  1 
ATOM   4977  C CD  . PRO B 1 184 ? -4.906  55.617  33.800  1.00 25.13  ? 184 PRO B CD  1 
ATOM   4978  N N   . VAL B 1 185 ? -2.356  58.114  32.874  1.00 28.37  ? 185 VAL B N   1 
ATOM   4979  C CA  . VAL B 1 185 ? -1.113  58.863  32.797  1.00 28.49  ? 185 VAL B CA  1 
ATOM   4980  C C   . VAL B 1 185 ? -0.485  58.647  31.425  1.00 26.40  ? 185 VAL B C   1 
ATOM   4981  O O   . VAL B 1 185 ? -0.103  59.602  30.765  1.00 27.53  ? 185 VAL B O   1 
ATOM   4982  C CB  . VAL B 1 185 ? -0.180  58.446  33.956  1.00 30.79  ? 185 VAL B CB  1 
ATOM   4983  C CG1 . VAL B 1 185 ? 1.215   59.047  33.860  1.00 28.86  ? 185 VAL B CG1 1 
ATOM   4984  C CG2 . VAL B 1 185 ? -0.788  58.798  35.318  1.00 32.88  ? 185 VAL B CG2 1 
ATOM   4985  N N   . ILE B 1 186 ? -0.424  57.393  30.979  1.00 24.53  ? 186 ILE B N   1 
ATOM   4986  C CA  . ILE B 1 186 ? 0.205   57.074  29.712  1.00 23.57  ? 186 ILE B CA  1 
ATOM   4987  C C   . ILE B 1 186 ? -0.568  57.725  28.568  1.00 25.04  ? 186 ILE B C   1 
ATOM   4988  O O   . ILE B 1 186 ? 0.022   58.389  27.709  1.00 29.81  ? 186 ILE B O   1 
ATOM   4989  C CB  . ILE B 1 186 ? 0.353   55.549  29.554  1.00 22.68  ? 186 ILE B CB  1 
ATOM   4990  C CG1 . ILE B 1 186 ? 1.202   54.973  30.715  1.00 22.82  ? 186 ILE B CG1 1 
ATOM   4991  C CG2 . ILE B 1 186 ? 0.924   55.182  28.175  1.00 20.83  ? 186 ILE B CG2 1 
ATOM   4992  C CD1 . ILE B 1 186 ? 1.465   53.475  30.627  1.00 23.27  ? 186 ILE B CD1 1 
ATOM   4993  N N   . ALA B 1 187 ? -1.894  57.574  28.582  1.00 23.86  ? 187 ALA B N   1 
ATOM   4994  C CA  . ALA B 1 187 ? -2.736  58.144  27.546  1.00 25.27  ? 187 ALA B CA  1 
ATOM   4995  C C   . ALA B 1 187 ? -2.551  59.659  27.473  1.00 26.48  ? 187 ALA B C   1 
ATOM   4996  O O   . ALA B 1 187 ? -2.331  60.227  26.404  1.00 30.26  ? 187 ALA B O   1 
ATOM   4997  C CB  . ALA B 1 187 ? -4.169  57.785  27.818  1.00 25.42  ? 187 ALA B CB  1 
ATOM   4998  N N   . ALA B 1 188 ? -2.610  60.318  28.624  1.00 26.06  ? 188 ALA B N   1 
ATOM   4999  C CA  . ALA B 1 188 ? -2.547  61.765  28.641  1.00 27.04  ? 188 ALA B CA  1 
ATOM   5000  C C   . ALA B 1 188 ? -1.192  62.234  28.098  1.00 28.45  ? 188 ALA B C   1 
ATOM   5001  O O   . ALA B 1 188 ? -1.118  63.208  27.331  1.00 27.43  ? 188 ALA B O   1 
ATOM   5002  C CB  . ALA B 1 188 ? -2.829  62.260  30.054  1.00 28.33  ? 188 ALA B CB  1 
ATOM   5003  N N   . TYR B 1 189 ? -0.120  61.523  28.490  1.00 27.07  ? 189 TYR B N   1 
ATOM   5004  C CA  . TYR B 1 189 ? 1.228   61.823  28.028  1.00 26.14  ? 189 TYR B CA  1 
ATOM   5005  C C   . TYR B 1 189 ? 1.237   61.859  26.504  1.00 23.76  ? 189 TYR B C   1 
ATOM   5006  O O   . TYR B 1 189 ? 1.643   62.861  25.906  1.00 21.85  ? 189 TYR B O   1 
ATOM   5007  C CB  . TYR B 1 189 ? 2.271   60.833  28.565  1.00 28.05  ? 189 TYR B CB  1 
ATOM   5008  C CG  . TYR B 1 189 ? 3.697   61.294  28.306  1.00 28.93  ? 189 TYR B CG  1 
ATOM   5009  C CD1 . TYR B 1 189 ? 4.314   62.249  29.111  1.00 29.85  ? 189 TYR B CD1 1 
ATOM   5010  C CD2 . TYR B 1 189 ? 4.397   60.831  27.194  1.00 31.81  ? 189 TYR B CD2 1 
ATOM   5011  C CE1 . TYR B 1 189 ? 5.605   62.701  28.836  1.00 31.42  ? 189 TYR B CE1 1 
ATOM   5012  C CE2 . TYR B 1 189 ? 5.672   61.286  26.907  1.00 32.39  ? 189 TYR B CE2 1 
ATOM   5013  C CZ  . TYR B 1 189 ? 6.279   62.209  27.733  1.00 31.27  ? 189 TYR B CZ  1 
ATOM   5014  O OH  . TYR B 1 189 ? 7.532   62.600  27.402  1.00 36.42  ? 189 TYR B OH  1 
ATOM   5015  N N   . ILE B 1 190 ? 0.714   60.780  25.911  1.00 23.54  ? 190 ILE B N   1 
ATOM   5016  C CA  . ILE B 1 190 ? 0.566   60.655  24.467  1.00 24.36  ? 190 ILE B CA  1 
ATOM   5017  C C   . ILE B 1 190 ? -0.242  61.824  23.894  1.00 24.72  ? 190 ILE B C   1 
ATOM   5018  O O   . ILE B 1 190 ? 0.137   62.391  22.873  1.00 23.98  ? 190 ILE B O   1 
ATOM   5019  C CB  . ILE B 1 190 ? -0.069  59.298  24.110  1.00 24.31  ? 190 ILE B CB  1 
ATOM   5020  C CG1 . ILE B 1 190 ? 0.879   58.123  24.429  1.00 23.72  ? 190 ILE B CG1 1 
ATOM   5021  C CG2 . ILE B 1 190 ? -0.500  59.282  22.649  1.00 24.55  ? 190 ILE B CG2 1 
ATOM   5022  C CD1 . ILE B 1 190 ? 0.174   56.794  24.638  1.00 24.19  ? 190 ILE B CD1 1 
ATOM   5023  N N   . TYR B 1 191 ? -1.360  62.168  24.544  1.00 25.09  ? 191 TYR B N   1 
ATOM   5024  C CA  . TYR B 1 191 ? -2.244  63.218  24.052  1.00 24.99  ? 191 TYR B CA  1 
ATOM   5025  C C   . TYR B 1 191 ? -1.504  64.546  24.055  1.00 22.47  ? 191 TYR B C   1 
ATOM   5026  O O   . TYR B 1 191 ? -1.602  65.344  23.130  1.00 19.87  ? 191 TYR B O   1 
ATOM   5027  C CB  . TYR B 1 191 ? -3.524  63.293  24.900  1.00 25.33  ? 191 TYR B CB  1 
ATOM   5028  C CG  . TYR B 1 191 ? -4.585  64.263  24.398  1.00 26.38  ? 191 TYR B CG  1 
ATOM   5029  C CD1 . TYR B 1 191 ? -5.303  63.997  23.244  1.00 29.13  ? 191 TYR B CD1 1 
ATOM   5030  C CD2 . TYR B 1 191 ? -4.919  65.411  25.106  1.00 29.99  ? 191 TYR B CD2 1 
ATOM   5031  C CE1 . TYR B 1 191 ? -6.267  64.875  22.768  1.00 29.28  ? 191 TYR B CE1 1 
ATOM   5032  C CE2 . TYR B 1 191 ? -5.899  66.285  24.654  1.00 29.41  ? 191 TYR B CE2 1 
ATOM   5033  C CZ  . TYR B 1 191 ? -6.571  66.012  23.481  1.00 27.80  ? 191 TYR B CZ  1 
ATOM   5034  O OH  . TYR B 1 191 ? -7.520  66.843  23.013  1.00 29.50  ? 191 TYR B OH  1 
ATOM   5035  N N   . ARG B 1 192 ? -0.792  64.792  25.150  1.00 24.60  ? 192 ARG B N   1 
ATOM   5036  C CA  . ARG B 1 192 ? -0.224  66.111  25.371  1.00 25.19  ? 192 ARG B CA  1 
ATOM   5037  C C   . ARG B 1 192 ? 0.960   66.319  24.441  1.00 24.12  ? 192 ARG B C   1 
ATOM   5038  O O   . ARG B 1 192 ? 1.130   67.409  23.890  1.00 23.60  ? 192 ARG B O   1 
ATOM   5039  C CB  . ARG B 1 192 ? 0.210   66.312  26.824  1.00 25.44  ? 192 ARG B CB  1 
ATOM   5040  C CG  . ARG B 1 192 ? -0.916  66.379  27.843  1.00 25.83  ? 192 ARG B CG  1 
ATOM   5041  C CD  . ARG B 1 192 ? -1.879  67.513  27.586  1.00 25.39  ? 192 ARG B CD  1 
ATOM   5042  N NE  . ARG B 1 192 ? -1.264  68.828  27.754  1.00 25.63  ? 192 ARG B NE  1 
ATOM   5043  C CZ  . ARG B 1 192 ? -1.961  69.972  27.738  1.00 28.23  ? 192 ARG B CZ  1 
ATOM   5044  N NH1 . ARG B 1 192 ? -3.283  69.979  27.587  1.00 27.83  ? 192 ARG B NH1 1 
ATOM   5045  N NH2 . ARG B 1 192 ? -1.326  71.122  27.875  1.00 28.01  ? 192 ARG B NH2 1 
ATOM   5046  N N   . ARG B 1 193 ? 1.760   65.255  24.281  1.00 24.76  ? 193 ARG B N   1 
ATOM   5047  C CA  . ARG B 1 193 ? 2.927   65.337  23.432  1.00 27.78  ? 193 ARG B CA  1 
ATOM   5048  C C   . ARG B 1 193 ? 2.473   65.516  21.980  1.00 26.81  ? 193 ARG B C   1 
ATOM   5049  O O   . ARG B 1 193 ? 2.956   66.397  21.269  1.00 28.77  ? 193 ARG B O   1 
ATOM   5050  C CB  . ARG B 1 193 ? 3.823   64.111  23.629  1.00 31.05  ? 193 ARG B CB  1 
ATOM   5051  C CG  . ARG B 1 193 ? 5.160   64.243  22.905  1.00 32.44  ? 193 ARG B CG  1 
ATOM   5052  C CD  . ARG B 1 193 ? 5.979   62.949  22.843  1.00 31.65  ? 193 ARG B CD  1 
ATOM   5053  N NE  . ARG B 1 193 ? 7.296   63.101  22.204  1.00 28.98  ? 193 ARG B NE  1 
ATOM   5054  C CZ  . ARG B 1 193 ? 7.836   62.171  21.424  1.00 26.53  ? 193 ARG B CZ  1 
ATOM   5055  N NH1 . ARG B 1 193 ? 7.301   60.970  21.341  1.00 27.87  ? 193 ARG B NH1 1 
ATOM   5056  N NH2 . ARG B 1 193 ? 8.928   62.411  20.750  1.00 24.77  ? 193 ARG B NH2 1 
ATOM   5057  N N   . LYS B 1 194 ? 1.523   64.687  21.543  1.00 25.59  ? 194 LYS B N   1 
ATOM   5058  C CA  . LYS B 1 194 ? 1.164   64.673  20.135  1.00 26.39  ? 194 LYS B CA  1 
ATOM   5059  C C   . LYS B 1 194 ? 0.369   65.931  19.770  1.00 25.57  ? 194 LYS B C   1 
ATOM   5060  O O   . LYS B 1 194 ? 0.656   66.546  18.758  1.00 26.97  ? 194 LYS B O   1 
ATOM   5061  C CB  . LYS B 1 194 ? 0.400   63.408  19.740  1.00 25.40  ? 194 LYS B CB  1 
ATOM   5062  C CG  . LYS B 1 194 ? 1.247   62.178  19.527  1.00 22.88  ? 194 LYS B CG  1 
ATOM   5063  C CD  . LYS B 1 194 ? 0.392   60.953  19.241  1.00 22.02  ? 194 LYS B CD  1 
ATOM   5064  C CE  . LYS B 1 194 ? -0.224  60.993  17.880  1.00 23.25  ? 194 LYS B CE  1 
ATOM   5065  N NZ  . LYS B 1 194 ? 0.703   61.031  16.747  1.00 22.67  ? 194 LYS B NZ  1 
ATOM   5066  N N   . TYR B 1 195 ? -0.564  66.366  20.615  1.00 24.20  ? 195 TYR B N   1 
ATOM   5067  C CA  . TYR B 1 195 ? -1.580  67.270  20.131  1.00 24.74  ? 195 TYR B CA  1 
ATOM   5068  C C   . TYR B 1 195 ? -1.645  68.593  20.877  1.00 27.49  ? 195 TYR B C   1 
ATOM   5069  O O   . TYR B 1 195 ? -2.322  69.496  20.390  1.00 24.87  ? 195 TYR B O   1 
ATOM   5070  C CB  . TYR B 1 195 ? -2.921  66.549  20.230  1.00 23.73  ? 195 TYR B CB  1 
ATOM   5071  C CG  . TYR B 1 195 ? -3.015  65.174  19.567  1.00 22.78  ? 195 TYR B CG  1 
ATOM   5072  C CD1 . TYR B 1 195 ? -2.969  65.024  18.181  1.00 21.52  ? 195 TYR B CD1 1 
ATOM   5073  C CD2 . TYR B 1 195 ? -3.209  64.035  20.335  1.00 20.24  ? 195 TYR B CD2 1 
ATOM   5074  C CE1 . TYR B 1 195 ? -3.080  63.774  17.592  1.00 21.24  ? 195 TYR B CE1 1 
ATOM   5075  C CE2 . TYR B 1 195 ? -3.398  62.795  19.751  1.00 20.69  ? 195 TYR B CE2 1 
ATOM   5076  C CZ  . TYR B 1 195 ? -3.320  62.656  18.381  1.00 21.07  ? 195 TYR B CZ  1 
ATOM   5077  O OH  . TYR B 1 195 ? -3.452  61.400  17.852  1.00 20.65  ? 195 TYR B OH  1 
ATOM   5078  N N   . LYS B 1 196 ? -0.992  68.720  22.045  1.00 30.81  ? 196 LYS B N   1 
ATOM   5079  C CA  . LYS B 1 196 ? -1.176  69.934  22.826  1.00 29.81  ? 196 LYS B CA  1 
ATOM   5080  C C   . LYS B 1 196 ? 0.139   70.637  23.150  1.00 32.10  ? 196 LYS B C   1 
ATOM   5081  O O   . LYS B 1 196 ? 0.228   71.367  24.135  1.00 34.83  ? 196 LYS B O   1 
ATOM   5082  C CB  . LYS B 1 196 ? -1.934  69.624  24.115  1.00 31.11  ? 196 LYS B CB  1 
ATOM   5083  C CG  . LYS B 1 196 ? -3.318  69.070  23.910  1.00 33.21  ? 196 LYS B CG  1 
ATOM   5084  C CD  . LYS B 1 196 ? -4.283  70.093  23.337  1.00 36.36  ? 196 LYS B CD  1 
ATOM   5085  C CE  . LYS B 1 196 ? -5.633  69.542  22.964  1.00 36.91  ? 196 LYS B CE  1 
ATOM   5086  N NZ  . LYS B 1 196 ? -6.364  70.611  22.282  1.00 35.52  ? 196 LYS B NZ  1 
ATOM   5087  N N   . GLY B 1 197 ? 1.155   70.465  22.311  1.00 31.96  ? 197 GLY B N   1 
ATOM   5088  C CA  . GLY B 1 197 ? 2.358   71.269  22.450  1.00 30.50  ? 197 GLY B CA  1 
ATOM   5089  C C   . GLY B 1 197 ? 3.306   70.746  23.526  1.00 28.46  ? 197 GLY B C   1 
ATOM   5090  O O   . GLY B 1 197 ? 4.107   71.512  24.032  1.00 28.34  ? 197 GLY B O   1 
ATOM   5091  N N   . ASP B 1 198 ? 3.207   69.459  23.879  1.00 27.98  ? 198 ASP B N   1 
ATOM   5092  C CA  . ASP B 1 198 ? 4.230   68.797  24.689  1.00 28.29  ? 198 ASP B CA  1 
ATOM   5093  C C   . ASP B 1 198 ? 4.435   69.506  26.037  1.00 28.54  ? 198 ASP B C   1 
ATOM   5094  O O   . ASP B 1 198 ? 5.546   69.548  26.539  1.00 26.48  ? 198 ASP B O   1 
ATOM   5095  C CB  . ASP B 1 198 ? 5.531   68.708  23.910  1.00 25.60  ? 198 ASP B CB  1 
ATOM   5096  C CG  . ASP B 1 198 ? 6.584   67.754  24.447  1.00 25.36  ? 198 ASP B CG  1 
ATOM   5097  O OD1 . ASP B 1 198 ? 6.198   66.812  25.230  1.00 23.63  ? 198 ASP B OD1 1 
ATOM   5098  O OD2 . ASP B 1 198 ? 7.770   67.964  24.058  1.00 20.29  ? 198 ASP B OD2 1 
ATOM   5099  N N   . THR B 1 199 ? 3.343   70.033  26.593  1.00 31.03  ? 199 THR B N   1 
ATOM   5100  C CA  . THR B 1 199 ? 3.179   70.549  27.944  1.00 34.91  ? 199 THR B CA  1 
ATOM   5101  C C   . THR B 1 199 ? 2.451   69.477  28.768  1.00 34.64  ? 199 THR B C   1 
ATOM   5102  O O   . THR B 1 199 ? 1.503   68.873  28.271  1.00 35.30  ? 199 THR B O   1 
ATOM   5103  C CB  . THR B 1 199 ? 2.353   71.826  27.722  1.00 46.15  ? 199 THR B CB  1 
ATOM   5104  O OG1 . THR B 1 199 ? 3.298   72.774  27.232  1.00 60.34  ? 199 THR B OG1 1 
ATOM   5105  C CG2 . THR B 1 199 ? 1.678   72.414  28.947  1.00 56.55  ? 199 THR B CG2 1 
ATOM   5106  N N   . HIS B 1 200 ? 2.828   69.263  30.042  1.00 34.41  ? 200 HIS B N   1 
ATOM   5107  C CA  . HIS B 1 200 ? 2.486   68.040  30.766  1.00 32.85  ? 200 HIS B CA  1 
ATOM   5108  C C   . HIS B 1 200 ? 1.805   68.347  32.098  1.00 33.63  ? 200 HIS B C   1 
ATOM   5109  O O   . HIS B 1 200 ? 2.331   69.084  32.897  1.00 38.68  ? 200 HIS B O   1 
ATOM   5110  C CB  . HIS B 1 200 ? 3.727   67.137  30.862  1.00 31.36  ? 200 HIS B CB  1 
ATOM   5111  C CG  . HIS B 1 200 ? 4.084   66.612  29.507  1.00 28.04  ? 200 HIS B CG  1 
ATOM   5112  N ND1 . HIS B 1 200 ? 3.476   65.493  28.974  1.00 28.06  ? 200 HIS B ND1 1 
ATOM   5113  C CD2 . HIS B 1 200 ? 4.890   67.081  28.548  1.00 27.44  ? 200 HIS B CD2 1 
ATOM   5114  C CE1 . HIS B 1 200 ? 3.935   65.282  27.740  1.00 25.52  ? 200 HIS B CE1 1 
ATOM   5115  N NE2 . HIS B 1 200 ? 4.794   66.236  27.456  1.00 27.02  ? 200 HIS B NE2 1 
ATOM   5116  N N   . ILE B 1 201 ? 0.609   67.797  32.327  1.00 36.17  ? 201 ILE B N   1 
ATOM   5117  C CA  . ILE B 1 201 ? -0.183  68.126  33.500  1.00 32.14  ? 201 ILE B CA  1 
ATOM   5118  C C   . ILE B 1 201 ? -0.248  66.912  34.409  1.00 30.32  ? 201 ILE B C   1 
ATOM   5119  O O   . ILE B 1 201 ? -0.605  65.827  33.941  1.00 25.63  ? 201 ILE B O   1 
ATOM   5120  C CB  . ILE B 1 201 ? -1.609  68.552  33.134  1.00 32.88  ? 201 ILE B CB  1 
ATOM   5121  C CG1 . ILE B 1 201 ? -1.601  69.762  32.217  1.00 34.93  ? 201 ILE B CG1 1 
ATOM   5122  C CG2 . ILE B 1 201 ? -2.385  68.810  34.421  1.00 30.16  ? 201 ILE B CG2 1 
ATOM   5123  C CD1 . ILE B 1 201 ? -2.850  69.907  31.377  1.00 35.05  ? 201 ILE B CD1 1 
ATOM   5124  N N   . ALA B 1 202 ? 0.087   67.144  35.691  1.00 26.95  ? 202 ALA B N   1 
ATOM   5125  C CA  . ALA B 1 202 ? 0.264   66.081  36.655  1.00 27.14  ? 202 ALA B CA  1 
ATOM   5126  C C   . ALA B 1 202 ? -1.096  65.628  37.183  1.00 28.20  ? 202 ALA B C   1 
ATOM   5127  O O   . ALA B 1 202 ? -2.091  66.355  37.106  1.00 26.51  ? 202 ALA B O   1 
ATOM   5128  C CB  . ALA B 1 202 ? 1.175   66.545  37.774  1.00 28.18  ? 202 ALA B CB  1 
ATOM   5129  N N   . PRO B 1 203 ? -1.159  64.405  37.754  1.00 28.32  ? 203 PRO B N   1 
ATOM   5130  C CA  . PRO B 1 203 ? -2.375  63.925  38.407  1.00 29.01  ? 203 PRO B CA  1 
ATOM   5131  C C   . PRO B 1 203 ? -2.855  64.868  39.508  1.00 29.08  ? 203 PRO B C   1 
ATOM   5132  O O   . PRO B 1 203 ? -2.047  65.497  40.166  1.00 31.29  ? 203 PRO B O   1 
ATOM   5133  C CB  . PRO B 1 203 ? -1.945  62.560  38.964  1.00 29.46  ? 203 PRO B CB  1 
ATOM   5134  C CG  . PRO B 1 203 ? -0.754  62.158  38.140  1.00 29.05  ? 203 PRO B CG  1 
ATOM   5135  C CD  . PRO B 1 203 ? -0.035  63.456  37.846  1.00 28.13  ? 203 PRO B CD  1 
ATOM   5136  N N   . ASP B 1 204 ? -4.175  65.001  39.678  1.00 33.91  ? 204 ASP B N   1 
ATOM   5137  C CA  . ASP B 1 204 ? -4.730  65.680  40.838  1.00 34.02  ? 204 ASP B CA  1 
ATOM   5138  C C   . ASP B 1 204 ? -5.217  64.631  41.826  1.00 35.53  ? 204 ASP B C   1 
ATOM   5139  O O   . ASP B 1 204 ? -6.151  63.901  41.528  1.00 36.60  ? 204 ASP B O   1 
ATOM   5140  C CB  . ASP B 1 204 ? -5.877  66.608  40.492  1.00 33.49  ? 204 ASP B CB  1 
ATOM   5141  C CG  . ASP B 1 204 ? -6.476  67.304  41.698  1.00 32.04  ? 204 ASP B CG  1 
ATOM   5142  O OD1 . ASP B 1 204 ? -6.333  66.763  42.813  1.00 33.00  ? 204 ASP B OD1 1 
ATOM   5143  O OD2 . ASP B 1 204 ? -7.027  68.401  41.507  1.00 30.85  ? 204 ASP B OD2 1 
ATOM   5144  N N   . PRO B 1 205 ? -4.609  64.533  43.026  1.00 38.36  ? 205 PRO B N   1 
ATOM   5145  C CA  . PRO B 1 205 ? -4.936  63.443  43.954  1.00 37.85  ? 205 PRO B CA  1 
ATOM   5146  C C   . PRO B 1 205 ? -6.339  63.493  44.560  1.00 37.73  ? 205 PRO B C   1 
ATOM   5147  O O   . PRO B 1 205 ? -6.749  62.549  45.235  1.00 35.54  ? 205 PRO B O   1 
ATOM   5148  C CB  . PRO B 1 205 ? -3.822  63.609  45.021  1.00 39.87  ? 205 PRO B CB  1 
ATOM   5149  C CG  . PRO B 1 205 ? -3.462  65.099  44.999  1.00 37.33  ? 205 PRO B CG  1 
ATOM   5150  C CD  . PRO B 1 205 ? -3.580  65.463  43.534  1.00 36.59  ? 205 PRO B CD  1 
ATOM   5151  N N   . ASN B 1 206 ? -7.068  64.595  44.319  1.00 39.52  ? 206 ASN B N   1 
ATOM   5152  C CA  . ASN B 1 206 ? -8.444  64.740  44.786  1.00 40.78  ? 206 ASN B CA  1 
ATOM   5153  C C   . ASN B 1 206 ? -9.492  64.321  43.750  1.00 40.87  ? 206 ASN B C   1 
ATOM   5154  O O   . ASN B 1 206 ? -10.688 64.381  44.067  1.00 36.90  ? 206 ASN B O   1 
ATOM   5155  C CB  . ASN B 1 206 ? -8.790  66.181  45.132  1.00 38.57  ? 206 ASN B CB  1 
ATOM   5156  C CG  . ASN B 1 206 ? -7.950  66.707  46.263  1.00 43.64  ? 206 ASN B CG  1 
ATOM   5157  O OD1 . ASN B 1 206 ? -7.619  65.963  47.196  1.00 44.65  ? 206 ASN B OD1 1 
ATOM   5158  N ND2 . ASN B 1 206 ? -7.589  67.976  46.186  1.00 43.73  ? 206 ASN B ND2 1 
ATOM   5159  N N   . LEU B 1 207 ? -9.059  63.955  42.523  1.00 37.84  ? 207 LEU B N   1 
ATOM   5160  C CA  . LEU B 1 207 ? -9.987  63.591  41.462  1.00 34.70  ? 207 LEU B CA  1 
ATOM   5161  C C   . LEU B 1 207 ? -10.057 62.073  41.323  1.00 32.98  ? 207 LEU B C   1 
ATOM   5162  O O   . LEU B 1 207 ? -9.098  61.358  41.618  1.00 31.35  ? 207 LEU B O   1 
ATOM   5163  C CB  . LEU B 1 207 ? -9.650  64.231  40.122  1.00 32.25  ? 207 LEU B CB  1 
ATOM   5164  C CG  . LEU B 1 207 ? -9.719  65.761  40.071  1.00 31.44  ? 207 LEU B CG  1 
ATOM   5165  C CD1 . LEU B 1 207 ? -9.209  66.257  38.722  1.00 29.18  ? 207 LEU B CD1 1 
ATOM   5166  C CD2 . LEU B 1 207 ? -11.123 66.290  40.347  1.00 30.76  ? 207 LEU B CD2 1 
ATOM   5167  N N   . ASP B 1 208 ? -11.221 61.611  40.853  1.00 29.86  ? 208 ASP B N   1 
ATOM   5168  C CA  . ASP B 1 208 ? -11.426 60.211  40.507  1.00 28.81  ? 208 ASP B CA  1 
ATOM   5169  C C   . ASP B 1 208 ? -10.688 59.862  39.202  1.00 27.55  ? 208 ASP B C   1 
ATOM   5170  O O   . ASP B 1 208 ? -10.213 60.743  38.470  1.00 26.52  ? 208 ASP B O   1 
ATOM   5171  C CB  . ASP B 1 208 ? -12.919 59.914  40.441  1.00 28.56  ? 208 ASP B CB  1 
ATOM   5172  C CG  . ASP B 1 208 ? -13.653 60.795  39.443  1.00 30.84  ? 208 ASP B CG  1 
ATOM   5173  O OD1 . ASP B 1 208 ? -13.844 61.973  39.799  1.00 31.36  ? 208 ASP B OD1 1 
ATOM   5174  O OD2 . ASP B 1 208 ? -13.958 60.304  38.306  1.00 30.91  ? 208 ASP B OD2 1 
ATOM   5175  N N   . TRP B 1 209 ? -10.649 58.561  38.884  1.00 24.43  ? 209 TRP B N   1 
ATOM   5176  C CA  . TRP B 1 209 ? -9.863  58.057  37.764  1.00 27.10  ? 209 TRP B CA  1 
ATOM   5177  C C   . TRP B 1 209 ? -10.242 58.744  36.442  1.00 29.38  ? 209 TRP B C   1 
ATOM   5178  O O   . TRP B 1 209 ? -9.396  59.346  35.780  1.00 29.86  ? 209 TRP B O   1 
ATOM   5179  C CB  . TRP B 1 209 ? -10.047 56.539  37.716  1.00 28.12  ? 209 TRP B CB  1 
ATOM   5180  C CG  . TRP B 1 209 ? -9.158  55.723  36.812  1.00 31.00  ? 209 TRP B CG  1 
ATOM   5181  C CD1 . TRP B 1 209 ? -7.847  55.362  36.986  1.00 29.07  ? 209 TRP B CD1 1 
ATOM   5182  C CD2 . TRP B 1 209 ? -9.628  54.994  35.659  1.00 28.51  ? 209 TRP B CD2 1 
ATOM   5183  N NE1 . TRP B 1 209 ? -7.461  54.512  35.987  1.00 28.87  ? 209 TRP B NE1 1 
ATOM   5184  C CE2 . TRP B 1 209 ? -8.533  54.250  35.176  1.00 27.40  ? 209 TRP B CE2 1 
ATOM   5185  C CE3 . TRP B 1 209 ? -10.855 54.922  34.994  1.00 26.13  ? 209 TRP B CE3 1 
ATOM   5186  C CZ2 . TRP B 1 209 ? -8.644  53.442  34.050  1.00 27.93  ? 209 TRP B CZ2 1 
ATOM   5187  C CZ3 . TRP B 1 209 ? -10.967 54.106  33.892  1.00 26.01  ? 209 TRP B CZ3 1 
ATOM   5188  C CH2 . TRP B 1 209 ? -9.885  53.347  33.452  1.00 27.85  ? 209 TRP B CH2 1 
ATOM   5189  N N   . SER B 1 210 ? -11.525 58.661  36.068  1.00 30.86  ? 210 SER B N   1 
ATOM   5190  C CA  . SER B 1 210 ? -12.033 59.220  34.824  1.00 30.15  ? 210 SER B CA  1 
ATOM   5191  C C   . SER B 1 210 ? -11.622 60.688  34.667  1.00 26.47  ? 210 SER B C   1 
ATOM   5192  O O   . SER B 1 210 ? -11.139 61.118  33.630  1.00 28.22  ? 210 SER B O   1 
ATOM   5193  C CB  . SER B 1 210 ? -13.555 59.038  34.741  1.00 30.98  ? 210 SER B CB  1 
ATOM   5194  O OG  . SER B 1 210 ? -13.927 57.661  34.714  1.00 29.82  ? 210 SER B OG  1 
ATOM   5195  N N   . ALA B 1 211 ? -11.832 61.473  35.698  1.00 25.41  ? 211 ALA B N   1 
ATOM   5196  C CA  . ALA B 1 211 ? -11.639 62.906  35.624  1.00 29.51  ? 211 ALA B CA  1 
ATOM   5197  C C   . ALA B 1 211 ? -10.158 63.284  35.611  1.00 28.82  ? 211 ALA B C   1 
ATOM   5198  O O   . ALA B 1 211 ? -9.791  64.315  35.031  1.00 29.30  ? 211 ALA B O   1 
ATOM   5199  C CB  . ALA B 1 211 ? -12.353 63.538  36.805  1.00 35.28  ? 211 ALA B CB  1 
ATOM   5200  N N   . ASN B 1 212 ? -9.309  62.494  36.286  1.00 29.69  ? 212 ASN B N   1 
ATOM   5201  C CA  . ASN B 1 212 ? -7.864  62.720  36.189  1.00 32.07  ? 212 ASN B CA  1 
ATOM   5202  C C   . ASN B 1 212 ? -7.438  62.650  34.720  1.00 31.04  ? 212 ASN B C   1 
ATOM   5203  O O   . ASN B 1 212 ? -6.619  63.480  34.295  1.00 28.76  ? 212 ASN B O   1 
ATOM   5204  C CB  . ASN B 1 212 ? -7.005  61.791  37.051  1.00 30.98  ? 212 ASN B CB  1 
ATOM   5205  C CG  . ASN B 1 212 ? -6.453  62.481  38.282  1.00 32.02  ? 212 ASN B CG  1 
ATOM   5206  O OD1 . ASN B 1 212 ? -5.833  63.543  38.203  1.00 33.89  ? 212 ASN B OD1 1 
ATOM   5207  N ND2 . ASN B 1 212 ? -6.676  61.911  39.449  1.00 34.45  ? 212 ASN B ND2 1 
ATOM   5208  N N   . LEU B 1 213 ? -8.003  61.671  33.977  1.00 25.03  ? 213 LEU B N   1 
ATOM   5209  C CA  . LEU B 1 213 ? -7.666  61.511  32.577  1.00 25.42  ? 213 LEU B CA  1 
ATOM   5210  C C   . LEU B 1 213 ? -8.023  62.816  31.880  1.00 26.14  ? 213 LEU B C   1 
ATOM   5211  O O   . LEU B 1 213 ? -7.254  63.349  31.092  1.00 31.89  ? 213 LEU B O   1 
ATOM   5212  C CB  . LEU B 1 213 ? -8.328  60.299  31.927  1.00 26.08  ? 213 LEU B CB  1 
ATOM   5213  C CG  . LEU B 1 213 ? -8.113  60.139  30.414  1.00 28.34  ? 213 LEU B CG  1 
ATOM   5214  C CD1 . LEU B 1 213 ? -6.647  60.174  30.072  1.00 32.39  ? 213 LEU B CD1 1 
ATOM   5215  C CD2 . LEU B 1 213 ? -8.701  58.872  29.858  1.00 27.53  ? 213 LEU B CD2 1 
ATOM   5216  N N   . ALA B 1 214 ? -9.194  63.347  32.183  1.00 24.65  ? 214 ALA B N   1 
ATOM   5217  C CA  . ALA B 1 214 ? -9.623  64.551  31.515  1.00 26.02  ? 214 ALA B CA  1 
ATOM   5218  C C   . ALA B 1 214 ? -8.705  65.687  31.935  1.00 27.38  ? 214 ALA B C   1 
ATOM   5219  O O   . ALA B 1 214 ? -8.280  66.476  31.103  1.00 30.41  ? 214 ALA B O   1 
ATOM   5220  C CB  . ALA B 1 214 ? -11.067 64.825  31.857  1.00 27.11  ? 214 ALA B CB  1 
ATOM   5221  N N   . HIS B 1 215 ? -8.405  65.735  33.237  1.00 29.23  ? 215 HIS B N   1 
ATOM   5222  C CA  . HIS B 1 215 ? -7.594  66.786  33.829  1.00 28.88  ? 215 HIS B CA  1 
ATOM   5223  C C   . HIS B 1 215 ? -6.211  66.830  33.184  1.00 27.52  ? 215 HIS B C   1 
ATOM   5224  O O   . HIS B 1 215 ? -5.763  67.898  32.762  1.00 23.86  ? 215 HIS B O   1 
ATOM   5225  C CB  . HIS B 1 215 ? -7.467  66.578  35.341  1.00 29.36  ? 215 HIS B CB  1 
ATOM   5226  C CG  . HIS B 1 215 ? -6.470  67.491  35.956  1.00 29.92  ? 215 HIS B CG  1 
ATOM   5227  N ND1 . HIS B 1 215 ? -6.660  68.856  36.007  1.00 31.93  ? 215 HIS B ND1 1 
ATOM   5228  C CD2 . HIS B 1 215 ? -5.260  67.261  36.494  1.00 29.80  ? 215 HIS B CD2 1 
ATOM   5229  C CE1 . HIS B 1 215 ? -5.599  69.425  36.572  1.00 29.48  ? 215 HIS B CE1 1 
ATOM   5230  N NE2 . HIS B 1 215 ? -4.739  68.477  36.889  1.00 28.84  ? 215 HIS B NE2 1 
ATOM   5231  N N   . MET B 1 216 ? -5.577  65.649  33.089  1.00 26.90  ? 216 MET B N   1 
ATOM   5232  C CA  . MET B 1 216 ? -4.230  65.494  32.551  1.00 25.67  ? 216 MET B CA  1 
ATOM   5233  C C   . MET B 1 216 ? -4.188  65.689  31.038  1.00 28.85  ? 216 MET B C   1 
ATOM   5234  O O   . MET B 1 216 ? -3.106  65.913  30.481  1.00 30.72  ? 216 MET B O   1 
ATOM   5235  C CB  . MET B 1 216 ? -3.669  64.112  32.889  1.00 25.30  ? 216 MET B CB  1 
ATOM   5236  C CG  . MET B 1 216 ? -3.366  63.997  34.365  1.00 26.06  ? 216 MET B CG  1 
ATOM   5237  S SD  . MET B 1 216 ? -2.514  62.487  34.819  1.00 28.62  ? 216 MET B SD  1 
ATOM   5238  C CE  . MET B 1 216 ? -3.745  61.188  34.673  1.00 30.36  ? 216 MET B CE  1 
ATOM   5239  N N   . MET B 1 217 ? -5.360  65.615  30.385  1.00 27.50  ? 217 MET B N   1 
ATOM   5240  C CA  . MET B 1 217 ? -5.470  65.930  28.974  1.00 27.88  ? 217 MET B CA  1 
ATOM   5241  C C   . MET B 1 217 ? -5.675  67.424  28.749  1.00 27.03  ? 217 MET B C   1 
ATOM   5242  O O   . MET B 1 217 ? -5.444  67.880  27.630  1.00 26.87  ? 217 MET B O   1 
ATOM   5243  C CB  . MET B 1 217 ? -6.629  65.170  28.321  1.00 30.86  ? 217 MET B CB  1 
ATOM   5244  C CG  . MET B 1 217 ? -6.336  63.707  28.089  1.00 33.69  ? 217 MET B CG  1 
ATOM   5245  S SD  . MET B 1 217 ? -7.764  62.759  27.537  1.00 31.53  ? 217 MET B SD  1 
ATOM   5246  C CE  . MET B 1 217 ? -7.995  63.599  25.959  1.00 32.93  ? 217 MET B CE  1 
ATOM   5247  N N   . GLY B 1 218 ? -6.170  68.160  29.762  1.00 27.46  ? 218 GLY B N   1 
ATOM   5248  C CA  . GLY B 1 218 ? -6.347  69.608  29.637  1.00 30.80  ? 218 GLY B CA  1 
ATOM   5249  C C   . GLY B 1 218 ? -7.805  70.095  29.706  1.00 33.50  ? 218 GLY B C   1 
ATOM   5250  O O   . GLY B 1 218 ? -8.076  71.261  29.452  1.00 36.79  ? 218 GLY B O   1 
ATOM   5251  N N   . PHE B 1 219 ? -8.746  69.223  30.081  1.00 36.40  ? 219 PHE B N   1 
ATOM   5252  C CA  . PHE B 1 219 ? -10.152 69.586  30.224  1.00 34.97  ? 219 PHE B CA  1 
ATOM   5253  C C   . PHE B 1 219 ? -10.561 69.424  31.684  1.00 31.24  ? 219 PHE B C   1 
ATOM   5254  O O   . PHE B 1 219 ? -10.419 68.347  32.259  1.00 30.65  ? 219 PHE B O   1 
ATOM   5255  C CB  . PHE B 1 219 ? -11.008 68.683  29.328  1.00 35.16  ? 219 PHE B CB  1 
ATOM   5256  C CG  . PHE B 1 219 ? -10.489 68.587  27.899  1.00 36.32  ? 219 PHE B CG  1 
ATOM   5257  C CD1 . PHE B 1 219 ? -10.830 69.553  26.959  1.00 35.90  ? 219 PHE B CD1 1 
ATOM   5258  C CD2 . PHE B 1 219 ? -9.616  67.570  27.518  1.00 33.65  ? 219 PHE B CD2 1 
ATOM   5259  C CE1 . PHE B 1 219 ? -10.330 69.492  25.663  1.00 38.23  ? 219 PHE B CE1 1 
ATOM   5260  C CE2 . PHE B 1 219 ? -9.119  67.515  26.228  1.00 35.35  ? 219 PHE B CE2 1 
ATOM   5261  C CZ  . PHE B 1 219 ? -9.477  68.476  25.296  1.00 36.88  ? 219 PHE B CZ  1 
ATOM   5262  N N   . ASP B 1 220 ? -11.066 70.503  32.283  1.00 35.18  ? 220 ASP B N   1 
ATOM   5263  C CA  . ASP B 1 220 ? -11.402 70.495  33.701  1.00 32.96  ? 220 ASP B CA  1 
ATOM   5264  C C   . ASP B 1 220 ? -12.865 70.854  33.939  1.00 31.18  ? 220 ASP B C   1 
ATOM   5265  O O   . ASP B 1 220 ? -13.269 70.933  35.088  1.00 36.92  ? 220 ASP B O   1 
ATOM   5266  C CB  . ASP B 1 220 ? -10.456 71.381  34.487  1.00 30.14  ? 220 ASP B CB  1 
ATOM   5267  C CG  . ASP B 1 220 ? -9.065  70.803  34.663  1.00 33.06  ? 220 ASP B CG  1 
ATOM   5268  O OD1 . ASP B 1 220 ? -8.958  69.753  35.318  1.00 34.32  ? 220 ASP B OD1 1 
ATOM   5269  O OD2 . ASP B 1 220 ? -8.103  71.404  34.141  1.00 31.81  ? 220 ASP B OD2 1 
ATOM   5270  N N   . ASP B 1 221 ? -13.677 71.038  32.893  1.00 33.96  ? 221 ASP B N   1 
ATOM   5271  C CA  . ASP B 1 221 ? -15.095 71.319  33.098  1.00 36.82  ? 221 ASP B CA  1 
ATOM   5272  C C   . ASP B 1 221 ? -15.790 70.103  33.704  1.00 36.07  ? 221 ASP B C   1 
ATOM   5273  O O   . ASP B 1 221 ? -15.465 68.949  33.375  1.00 31.42  ? 221 ASP B O   1 
ATOM   5274  C CB  . ASP B 1 221 ? -15.803 71.757  31.831  1.00 41.47  ? 221 ASP B CB  1 
ATOM   5275  C CG  . ASP B 1 221 ? -15.751 73.253  31.551  1.00 56.34  ? 221 ASP B CG  1 
ATOM   5276  O OD1 . ASP B 1 221 ? -14.637 73.845  31.525  1.00 51.26  ? 221 ASP B OD1 1 
ATOM   5277  O OD2 . ASP B 1 221 ? -16.839 73.829  31.356  1.00 73.44  ? 221 ASP B OD2 1 
ATOM   5278  N N   . PHE B 1 222 ? -16.755 70.402  34.586  1.00 35.25  ? 222 PHE B N   1 
ATOM   5279  C CA  . PHE B 1 222 ? -17.514 69.397  35.317  1.00 37.92  ? 222 PHE B CA  1 
ATOM   5280  C C   . PHE B 1 222 ? -18.228 68.446  34.357  1.00 33.70  ? 222 PHE B C   1 
ATOM   5281  O O   . PHE B 1 222 ? -18.231 67.230  34.536  1.00 32.70  ? 222 PHE B O   1 
ATOM   5282  C CB  . PHE B 1 222 ? -18.474 70.121  36.271  1.00 46.93  ? 222 PHE B CB  1 
ATOM   5283  C CG  . PHE B 1 222 ? -19.430 69.182  37.000  1.00 53.55  ? 222 PHE B CG  1 
ATOM   5284  C CD1 . PHE B 1 222 ? -18.982 68.371  38.042  1.00 50.74  ? 222 PHE B CD1 1 
ATOM   5285  C CD2 . PHE B 1 222 ? -20.761 69.070  36.587  1.00 55.78  ? 222 PHE B CD2 1 
ATOM   5286  C CE1 . PHE B 1 222 ? -19.852 67.480  38.653  1.00 51.41  ? 222 PHE B CE1 1 
ATOM   5287  C CE2 . PHE B 1 222 ? -21.623 68.178  37.202  1.00 50.40  ? 222 PHE B CE2 1 
ATOM   5288  C CZ  . PHE B 1 222 ? -21.168 67.384  38.223  1.00 49.79  ? 222 PHE B CZ  1 
ATOM   5289  N N   . GLU B 1 223 ? -18.838 69.001  33.317  1.00 36.70  ? 223 GLU B N   1 
ATOM   5290  C CA  . GLU B 1 223 ? -19.545 68.186  32.344  1.00 35.21  ? 223 GLU B CA  1 
ATOM   5291  C C   . GLU B 1 223 ? -18.568 67.254  31.631  1.00 28.50  ? 223 GLU B C   1 
ATOM   5292  O O   . GLU B 1 223 ? -18.906 66.125  31.304  1.00 27.37  ? 223 GLU B O   1 
ATOM   5293  C CB  . GLU B 1 223 ? -20.300 69.066  31.346  1.00 40.54  ? 223 GLU B CB  1 
ATOM   5294  C CG  . GLU B 1 223 ? -21.366 69.968  31.965  1.00 41.92  ? 223 GLU B CG  1 
ATOM   5295  C CD  . GLU B 1 223 ? -22.099 70.882  30.986  1.00 45.47  ? 223 GLU B CD  1 
ATOM   5296  O OE1 . GLU B 1 223 ? -22.609 71.862  31.571  1.00 44.69  ? 223 GLU B OE1 1 
ATOM   5297  O OE2 . GLU B 1 223 ? -22.172 70.669  29.724  1.00 41.79  ? 223 GLU B OE2 1 
ATOM   5298  N N   . VAL B 1 224 ? -17.343 67.711  31.375  1.00 27.69  ? 224 VAL B N   1 
ATOM   5299  C CA  . VAL B 1 224 ? -16.374 66.833  30.732  1.00 28.14  ? 224 VAL B CA  1 
ATOM   5300  C C   . VAL B 1 224 ? -16.008 65.712  31.711  1.00 28.59  ? 224 VAL B C   1 
ATOM   5301  O O   . VAL B 1 224 ? -15.961 64.550  31.308  1.00 27.46  ? 224 VAL B O   1 
ATOM   5302  C CB  . VAL B 1 224 ? -15.111 67.501  30.158  1.00 27.26  ? 224 VAL B CB  1 
ATOM   5303  C CG1 . VAL B 1 224 ? -14.318 66.532  29.279  1.00 25.20  ? 224 VAL B CG1 1 
ATOM   5304  C CG2 . VAL B 1 224 ? -15.456 68.770  29.385  1.00 27.10  ? 224 VAL B CG2 1 
ATOM   5305  N N   . TYR B 1 225 ? -15.788 66.034  32.998  1.00 27.05  ? 225 TYR B N   1 
ATOM   5306  C CA  . TYR B 1 225 ? -15.550 64.971  33.951  1.00 28.40  ? 225 TYR B CA  1 
ATOM   5307  C C   . TYR B 1 225 ? -16.712 63.971  33.876  1.00 31.40  ? 225 TYR B C   1 
ATOM   5308  O O   . TYR B 1 225 ? -16.479 62.744  33.874  1.00 31.33  ? 225 TYR B O   1 
ATOM   5309  C CB  . TYR B 1 225 ? -15.314 65.495  35.375  1.00 32.81  ? 225 TYR B CB  1 
ATOM   5310  C CG  . TYR B 1 225 ? -14.073 66.340  35.675  1.00 35.40  ? 225 TYR B CG  1 
ATOM   5311  C CD1 . TYR B 1 225 ? -12.995 66.449  34.785  1.00 39.66  ? 225 TYR B CD1 1 
ATOM   5312  C CD2 . TYR B 1 225 ? -13.971 67.018  36.889  1.00 33.85  ? 225 TYR B CD2 1 
ATOM   5313  C CE1 . TYR B 1 225 ? -11.876 67.217  35.084  1.00 38.52  ? 225 TYR B CE1 1 
ATOM   5314  C CE2 . TYR B 1 225 ? -12.862 67.785  37.197  1.00 33.76  ? 225 TYR B CE2 1 
ATOM   5315  C CZ  . TYR B 1 225 ? -11.819 67.891  36.294  1.00 36.36  ? 225 TYR B CZ  1 
ATOM   5316  O OH  . TYR B 1 225 ? -10.770 68.697  36.605  1.00 36.54  ? 225 TYR B OH  1 
ATOM   5317  N N   . GLU B 1 226 ? -17.964 64.491  33.814  1.00 30.51  ? 226 GLU B N   1 
ATOM   5318  C CA  . GLU B 1 226 ? -19.160 63.644  33.768  1.00 27.28  ? 226 GLU B CA  1 
ATOM   5319  C C   . GLU B 1 226 ? -19.164 62.765  32.506  1.00 27.53  ? 226 GLU B C   1 
ATOM   5320  O O   . GLU B 1 226 ? -19.450 61.560  32.542  1.00 24.76  ? 226 GLU B O   1 
ATOM   5321  C CB  . GLU B 1 226 ? -20.398 64.533  33.913  1.00 27.14  ? 226 GLU B CB  1 
ATOM   5322  C CG  . GLU B 1 226 ? -20.624 65.028  35.347  1.00 28.51  ? 226 GLU B CG  1 
ATOM   5323  C CD  . GLU B 1 226 ? -21.078 63.962  36.330  1.00 26.67  ? 226 GLU B CD  1 
ATOM   5324  O OE1 . GLU B 1 226 ? -20.174 63.377  36.954  1.00 29.15  ? 226 GLU B OE1 1 
ATOM   5325  O OE2 . GLU B 1 226 ? -22.294 63.707  36.479  1.00 24.57  ? 226 GLU B OE2 1 
ATOM   5326  N N   . LEU B 1 227 ? -18.858 63.382  31.362  1.00 27.51  ? 227 LEU B N   1 
ATOM   5327  C CA  . LEU B 1 227 ? -18.723 62.642  30.125  1.00 27.54  ? 227 LEU B CA  1 
ATOM   5328  C C   . LEU B 1 227 ? -17.735 61.493  30.311  1.00 26.52  ? 227 LEU B C   1 
ATOM   5329  O O   . LEU B 1 227 ? -18.018 60.342  29.948  1.00 23.80  ? 227 LEU B O   1 
ATOM   5330  C CB  . LEU B 1 227 ? -18.259 63.607  29.041  1.00 28.33  ? 227 LEU B CB  1 
ATOM   5331  C CG  . LEU B 1 227 ? -17.940 62.963  27.688  1.00 30.27  ? 227 LEU B CG  1 
ATOM   5332  C CD1 . LEU B 1 227 ? -19.129 62.203  27.076  1.00 27.47  ? 227 LEU B CD1 1 
ATOM   5333  C CD2 . LEU B 1 227 ? -17.418 64.054  26.751  1.00 31.54  ? 227 LEU B CD2 1 
ATOM   5334  N N   . PHE B 1 228 ? -16.562 61.810  30.873  1.00 27.21  ? 228 PHE B N   1 
ATOM   5335  C CA  . PHE B 1 228 ? -15.488 60.819  30.931  1.00 30.25  ? 228 PHE B CA  1 
ATOM   5336  C C   . PHE B 1 228 ? -15.937 59.641  31.807  1.00 30.78  ? 228 PHE B C   1 
ATOM   5337  O O   . PHE B 1 228 ? -15.703 58.469  31.468  1.00 27.25  ? 228 PHE B O   1 
ATOM   5338  C CB  . PHE B 1 228 ? -14.148 61.437  31.357  1.00 29.05  ? 228 PHE B CB  1 
ATOM   5339  C CG  . PHE B 1 228 ? -13.337 62.005  30.197  1.00 30.28  ? 228 PHE B CG  1 
ATOM   5340  C CD1 . PHE B 1 228 ? -13.923 62.861  29.263  1.00 30.52  ? 228 PHE B CD1 1 
ATOM   5341  C CD2 . PHE B 1 228 ? -12.008 61.629  30.001  1.00 30.26  ? 228 PHE B CD2 1 
ATOM   5342  C CE1 . PHE B 1 228 ? -13.199 63.356  28.190  1.00 30.38  ? 228 PHE B CE1 1 
ATOM   5343  C CE2 . PHE B 1 228 ? -11.285 62.119  28.923  1.00 31.78  ? 228 PHE B CE2 1 
ATOM   5344  C CZ  . PHE B 1 228 ? -11.874 62.992  28.029  1.00 32.59  ? 228 PHE B CZ  1 
ATOM   5345  N N   . ARG B 1 229 ? -16.618 59.970  32.915  1.00 28.48  ? 229 ARG B N   1 
ATOM   5346  C CA  . ARG B 1 229 ? -17.138 58.952  33.822  1.00 31.67  ? 229 ARG B CA  1 
ATOM   5347  C C   . ARG B 1 229 ? -18.031 57.966  33.065  1.00 28.94  ? 229 ARG B C   1 
ATOM   5348  O O   . ARG B 1 229 ? -17.799 56.749  33.088  1.00 27.51  ? 229 ARG B O   1 
ATOM   5349  C CB  . ARG B 1 229 ? -17.803 59.626  35.037  1.00 31.46  ? 229 ARG B CB  1 
ATOM   5350  C CG  . ARG B 1 229 ? -16.793 60.354  35.924  1.00 30.97  ? 229 ARG B CG  1 
ATOM   5351  C CD  . ARG B 1 229 ? -17.391 61.326  36.903  1.00 31.24  ? 229 ARG B CD  1 
ATOM   5352  N NE  . ARG B 1 229 ? -16.387 61.973  37.750  1.00 28.59  ? 229 ARG B NE  1 
ATOM   5353  C CZ  . ARG B 1 229 ? -16.517 63.237  38.151  1.00 29.14  ? 229 ARG B CZ  1 
ATOM   5354  N NH1 . ARG B 1 229 ? -17.609 63.921  37.879  1.00 28.59  ? 229 ARG B NH1 1 
ATOM   5355  N NH2 . ARG B 1 229 ? -15.561 63.840  38.818  1.00 30.07  ? 229 ARG B NH2 1 
ATOM   5356  N N   . LEU B 1 230 ? -19.039 58.520  32.384  1.00 28.63  ? 230 LEU B N   1 
ATOM   5357  C CA  . LEU B 1 230 ? -19.971 57.747  31.579  1.00 28.79  ? 230 LEU B CA  1 
ATOM   5358  C C   . LEU B 1 230 ? -19.258 56.993  30.459  1.00 27.90  ? 230 LEU B C   1 
ATOM   5359  O O   . LEU B 1 230 ? -19.528 55.825  30.199  1.00 24.09  ? 230 LEU B O   1 
ATOM   5360  C CB  . LEU B 1 230 ? -20.992 58.725  31.008  1.00 29.17  ? 230 LEU B CB  1 
ATOM   5361  C CG  . LEU B 1 230 ? -22.099 58.108  30.156  1.00 29.28  ? 230 LEU B CG  1 
ATOM   5362  C CD1 . LEU B 1 230 ? -22.819 57.003  30.917  1.00 31.12  ? 230 LEU B CD1 1 
ATOM   5363  C CD2 . LEU B 1 230 ? -23.085 59.171  29.704  1.00 31.17  ? 230 LEU B CD2 1 
ATOM   5364  N N   . TYR B 1 231 ? -18.352 57.681  29.768  1.00 29.17  ? 231 TYR B N   1 
ATOM   5365  C CA  . TYR B 1 231 ? -17.644 57.041  28.677  1.00 30.89  ? 231 TYR B CA  1 
ATOM   5366  C C   . TYR B 1 231 ? -16.972 55.777  29.208  1.00 26.20  ? 231 TYR B C   1 
ATOM   5367  O O   . TYR B 1 231 ? -17.088 54.703  28.618  1.00 25.09  ? 231 TYR B O   1 
ATOM   5368  C CB  . TYR B 1 231 ? -16.661 58.023  28.031  1.00 34.14  ? 231 TYR B CB  1 
ATOM   5369  C CG  . TYR B 1 231 ? -15.993 57.434  26.803  1.00 35.47  ? 231 TYR B CG  1 
ATOM   5370  C CD1 . TYR B 1 231 ? -14.866 56.632  26.908  1.00 35.23  ? 231 TYR B CD1 1 
ATOM   5371  C CD2 . TYR B 1 231 ? -16.505 57.672  25.538  1.00 43.00  ? 231 TYR B CD2 1 
ATOM   5372  C CE1 . TYR B 1 231 ? -14.264 56.083  25.784  1.00 38.74  ? 231 TYR B CE1 1 
ATOM   5373  C CE2 . TYR B 1 231 ? -15.912 57.137  24.402  1.00 44.03  ? 231 TYR B CE2 1 
ATOM   5374  C CZ  . TYR B 1 231 ? -14.790 56.332  24.525  1.00 45.24  ? 231 TYR B CZ  1 
ATOM   5375  O OH  . TYR B 1 231 ? -14.222 55.819  23.381  1.00 56.10  ? 231 TYR B OH  1 
ATOM   5376  N N   . MET B 1 232 ? -16.247 55.938  30.311  1.00 25.89  ? 232 MET B N   1 
ATOM   5377  C CA  . MET B 1 232 ? -15.429 54.869  30.843  1.00 27.03  ? 232 MET B CA  1 
ATOM   5378  C C   . MET B 1 232 ? -16.344 53.730  31.289  1.00 28.80  ? 232 MET B C   1 
ATOM   5379  O O   . MET B 1 232 ? -16.015 52.553  31.092  1.00 27.13  ? 232 MET B O   1 
ATOM   5380  C CB  . MET B 1 232 ? -14.554 55.383  31.991  1.00 28.32  ? 232 MET B CB  1 
ATOM   5381  C CG  . MET B 1 232 ? -13.403 56.279  31.574  1.00 30.86  ? 232 MET B CG  1 
ATOM   5382  S SD  . MET B 1 232 ? -12.278 55.507  30.395  1.00 34.72  ? 232 MET B SD  1 
ATOM   5383  C CE  . MET B 1 232 ? -12.011 56.891  29.292  1.00 37.60  ? 232 MET B CE  1 
ATOM   5384  N N   . PHE B 1 233 ? -17.505 54.116  31.851  1.00 28.40  ? 233 PHE B N   1 
ATOM   5385  C CA  . PHE B 1 233 ? -18.528 53.189  32.304  1.00 25.57  ? 233 PHE B CA  1 
ATOM   5386  C C   . PHE B 1 233 ? -19.044 52.347  31.139  1.00 24.29  ? 233 PHE B C   1 
ATOM   5387  O O   . PHE B 1 233 ? -19.055 51.107  31.175  1.00 23.32  ? 233 PHE B O   1 
ATOM   5388  C CB  . PHE B 1 233 ? -19.622 54.058  32.933  1.00 24.99  ? 233 PHE B CB  1 
ATOM   5389  C CG  . PHE B 1 233 ? -20.865 53.250  33.280  1.00 27.39  ? 233 PHE B CG  1 
ATOM   5390  C CD1 . PHE B 1 233 ? -20.895 52.430  34.408  1.00 28.84  ? 233 PHE B CD1 1 
ATOM   5391  C CD2 . PHE B 1 233 ? -21.991 53.294  32.469  1.00 30.81  ? 233 PHE B CD2 1 
ATOM   5392  C CE1 . PHE B 1 233 ? -22.012 51.675  34.715  1.00 30.74  ? 233 PHE B CE1 1 
ATOM   5393  C CE2 . PHE B 1 233 ? -23.133 52.568  32.800  1.00 34.92  ? 233 PHE B CE2 1 
ATOM   5394  C CZ  . PHE B 1 233 ? -23.141 51.757  33.922  1.00 34.26  ? 233 PHE B CZ  1 
ATOM   5395  N N   . LEU B 1 234 ? -19.472 53.057  30.089  1.00 25.15  ? 234 LEU B N   1 
ATOM   5396  C CA  . LEU B 1 234 ? -20.211 52.480  28.976  1.00 25.05  ? 234 LEU B CA  1 
ATOM   5397  C C   . LEU B 1 234 ? -19.347 51.508  28.177  1.00 26.60  ? 234 LEU B C   1 
ATOM   5398  O O   . LEU B 1 234 ? -19.831 50.447  27.810  1.00 23.21  ? 234 LEU B O   1 
ATOM   5399  C CB  . LEU B 1 234 ? -20.738 53.624  28.111  1.00 26.06  ? 234 LEU B CB  1 
ATOM   5400  C CG  . LEU B 1 234 ? -21.972 54.354  28.655  1.00 26.43  ? 234 LEU B CG  1 
ATOM   5401  C CD1 . LEU B 1 234 ? -22.404 55.417  27.685  1.00 26.65  ? 234 LEU B CD1 1 
ATOM   5402  C CD2 . LEU B 1 234 ? -23.139 53.404  28.940  1.00 25.15  ? 234 LEU B CD2 1 
ATOM   5403  N N   . HIS B 1 235 ? -18.068 51.872  27.959  1.00 29.14  ? 235 HIS B N   1 
ATOM   5404  C CA  . HIS B 1 235 ? -17.161 51.155  27.077  1.00 29.75  ? 235 HIS B CA  1 
ATOM   5405  C C   . HIS B 1 235 ? -16.332 50.119  27.840  1.00 31.88  ? 235 HIS B C   1 
ATOM   5406  O O   . HIS B 1 235 ? -15.388 49.542  27.290  1.00 33.49  ? 235 HIS B O   1 
ATOM   5407  C CB  . HIS B 1 235 ? -16.242 52.170  26.397  1.00 29.71  ? 235 HIS B CB  1 
ATOM   5408  C CG  . HIS B 1 235 ? -16.925 53.062  25.443  1.00 30.96  ? 235 HIS B CG  1 
ATOM   5409  N ND1 . HIS B 1 235 ? -17.525 54.232  25.848  1.00 32.53  ? 235 HIS B ND1 1 
ATOM   5410  C CD2 . HIS B 1 235 ? -17.114 52.964  24.106  1.00 31.70  ? 235 HIS B CD2 1 
ATOM   5411  C CE1 . HIS B 1 235 ? -18.051 54.824  24.771  1.00 33.22  ? 235 HIS B CE1 1 
ATOM   5412  N NE2 . HIS B 1 235 ? -17.807 54.074  23.702  1.00 29.51  ? 235 HIS B NE2 1 
ATOM   5413  N N   . SER B 1 236 ? -16.735 49.838  29.084  1.00 28.63  ? 236 SER B N   1 
ATOM   5414  C CA  . SER B 1 236 ? -15.933 49.063  30.013  1.00 27.93  ? 236 SER B CA  1 
ATOM   5415  C C   . SER B 1 236 ? -15.722 47.624  29.561  1.00 26.19  ? 236 SER B C   1 
ATOM   5416  O O   . SER B 1 236 ? -14.645 47.080  29.778  1.00 26.73  ? 236 SER B O   1 
ATOM   5417  C CB  . SER B 1 236 ? -16.557 49.074  31.383  1.00 26.79  ? 236 SER B CB  1 
ATOM   5418  O OG  . SER B 1 236 ? -17.783 48.358  31.354  1.00 27.67  ? 236 SER B OG  1 
ATOM   5419  N N   . ASP B 1 237 ? -16.776 46.991  29.039  1.00 28.49  ? 237 ASP B N   1 
ATOM   5420  C CA  . ASP B 1 237 ? -16.816 45.547  28.831  1.00 29.81  ? 237 ASP B CA  1 
ATOM   5421  C C   . ASP B 1 237 ? -17.943 45.213  27.858  1.00 32.84  ? 237 ASP B C   1 
ATOM   5422  O O   . ASP B 1 237 ? -18.947 45.925  27.806  1.00 34.42  ? 237 ASP B O   1 
ATOM   5423  C CB  . ASP B 1 237 ? -17.058 44.813  30.138  1.00 32.45  ? 237 ASP B CB  1 
ATOM   5424  C CG  . ASP B 1 237 ? -16.677 43.339  30.177  1.00 36.44  ? 237 ASP B CG  1 
ATOM   5425  O OD1 . ASP B 1 237 ? -15.521 43.030  29.807  1.00 39.38  ? 237 ASP B OD1 1 
ATOM   5426  O OD2 . ASP B 1 237 ? -17.516 42.516  30.643  1.00 34.17  ? 237 ASP B OD2 1 
ATOM   5427  N N   . HIS B 1 238 ? -17.779 44.116  27.106  1.00 30.28  ? 238 HIS B N   1 
ATOM   5428  C CA  . HIS B 1 238 ? -18.782 43.675  26.156  1.00 27.26  ? 238 HIS B CA  1 
ATOM   5429  C C   . HIS B 1 238 ? -18.448 42.250  25.748  1.00 26.98  ? 238 HIS B C   1 
ATOM   5430  O O   . HIS B 1 238 ? -17.999 42.010  24.631  1.00 25.95  ? 238 HIS B O   1 
ATOM   5431  C CB  . HIS B 1 238 ? -18.814 44.592  24.931  1.00 29.42  ? 238 HIS B CB  1 
ATOM   5432  C CG  . HIS B 1 238 ? -20.035 44.484  24.074  1.00 35.66  ? 238 HIS B CG  1 
ATOM   5433  N ND1 . HIS B 1 238 ? -20.164 43.692  22.944  1.00 37.05  ? 238 HIS B ND1 1 
ATOM   5434  C CD2 . HIS B 1 238 ? -21.203 45.130  24.206  1.00 35.38  ? 238 HIS B CD2 1 
ATOM   5435  C CE1 . HIS B 1 238 ? -21.369 43.861  22.413  1.00 32.96  ? 238 HIS B CE1 1 
ATOM   5436  N NE2 . HIS B 1 238 ? -22.013 44.739  23.160  1.00 39.17  ? 238 HIS B NE2 1 
ATOM   5437  N N   . GLU B 1 239 ? -18.659 41.312  26.676  1.00 27.01  ? 239 GLU B N   1 
ATOM   5438  C CA  . GLU B 1 239 ? -18.399 39.897  26.442  1.00 26.59  ? 239 GLU B CA  1 
ATOM   5439  C C   . GLU B 1 239 ? -16.895 39.708  26.225  1.00 27.77  ? 239 GLU B C   1 
ATOM   5440  O O   . GLU B 1 239 ? -16.117 40.627  26.494  1.00 29.56  ? 239 GLU B O   1 
ATOM   5441  C CB  . GLU B 1 239 ? -19.305 39.329  25.350  1.00 26.03  ? 239 GLU B CB  1 
ATOM   5442  C CG  . GLU B 1 239 ? -20.700 39.002  25.861  1.00 26.72  ? 239 GLU B CG  1 
ATOM   5443  C CD  . GLU B 1 239 ? -21.619 38.211  24.933  1.00 30.33  ? 239 GLU B CD  1 
ATOM   5444  O OE1 . GLU B 1 239 ? -22.639 37.756  25.455  1.00 35.86  ? 239 GLU B OE1 1 
ATOM   5445  O OE2 . GLU B 1 239 ? -21.387 38.034  23.733  1.00 35.66  ? 239 GLU B OE2 1 
ATOM   5446  N N   . GLY B 1 240 ? -16.491 38.491  25.828  1.00 26.38  ? 240 GLY B N   1 
ATOM   5447  C CA  . GLY B 1 240 ? -15.086 38.172  25.661  1.00 26.63  ? 240 GLY B CA  1 
ATOM   5448  C C   . GLY B 1 240 ? -14.763 37.789  24.229  1.00 29.49  ? 240 GLY B C   1 
ATOM   5449  O O   . GLY B 1 240 ? -13.625 37.466  23.921  1.00 35.00  ? 240 GLY B O   1 
ATOM   5450  N N   . GLY B 1 241 ? -15.765 37.853  23.355  1.00 31.79  ? 241 GLY B N   1 
ATOM   5451  C CA  . GLY B 1 241 ? -15.624 37.351  22.002  1.00 32.80  ? 241 GLY B CA  1 
ATOM   5452  C C   . GLY B 1 241 ? -14.906 38.326  21.067  1.00 33.19  ? 241 GLY B C   1 
ATOM   5453  O O   . GLY B 1 241 ? -14.296 37.892  20.090  1.00 33.11  ? 241 GLY B O   1 
ATOM   5454  N N   . ASN B 1 242 ? -14.999 39.633  21.354  1.00 31.87  ? 242 ASN B N   1 
ATOM   5455  C CA  . ASN B 1 242 ? -14.356 40.656  20.550  1.00 28.11  ? 242 ASN B CA  1 
ATOM   5456  C C   . ASN B 1 242 ? -12.828 40.463  20.623  1.00 27.97  ? 242 ASN B C   1 
ATOM   5457  O O   . ASN B 1 242 ? -12.301 39.840  21.546  1.00 21.42  ? 242 ASN B O   1 
ATOM   5458  C CB  . ASN B 1 242 ? -14.843 42.040  20.962  1.00 27.72  ? 242 ASN B CB  1 
ATOM   5459  C CG  . ASN B 1 242 ? -14.342 42.467  22.325  1.00 34.66  ? 242 ASN B CG  1 
ATOM   5460  O OD1 . ASN B 1 242 ? -13.159 42.814  22.484  1.00 38.98  ? 242 ASN B OD1 1 
ATOM   5461  N ND2 . ASN B 1 242 ? -15.226 42.500  23.319  1.00 35.53  ? 242 ASN B ND2 1 
ATOM   5462  N N   . VAL B 1 243 ? -12.140 40.997  19.603  1.00 28.48  ? 243 VAL B N   1 
ATOM   5463  C CA  . VAL B 1 243 ? -10.733 40.758  19.322  1.00 28.91  ? 243 VAL B CA  1 
ATOM   5464  C C   . VAL B 1 243 ? -9.876  41.199  20.497  1.00 28.90  ? 243 VAL B C   1 
ATOM   5465  O O   . VAL B 1 243 ? -9.052  40.427  20.957  1.00 28.54  ? 243 VAL B O   1 
ATOM   5466  C CB  . VAL B 1 243 ? -10.347 41.510  18.042  1.00 28.66  ? 243 VAL B CB  1 
ATOM   5467  C CG1 . VAL B 1 243 ? -8.837  41.626  17.879  1.00 32.57  ? 243 VAL B CG1 1 
ATOM   5468  C CG2 . VAL B 1 243 ? -10.956 40.830  16.832  1.00 28.99  ? 243 VAL B CG2 1 
ATOM   5469  N N   . SER B 1 244 ? -10.127 42.413  21.007  1.00 30.55  ? 244 SER B N   1 
ATOM   5470  C CA  . SER B 1 244 ? -9.354  42.955  22.110  1.00 29.48  ? 244 SER B CA  1 
ATOM   5471  C C   . SER B 1 244 ? -9.525  42.077  23.344  1.00 29.99  ? 244 SER B C   1 
ATOM   5472  O O   . SER B 1 244 ? -8.535  41.629  23.918  1.00 30.11  ? 244 SER B O   1 
ATOM   5473  C CB  . SER B 1 244 ? -9.614  44.446  22.390  1.00 27.58  ? 244 SER B CB  1 
ATOM   5474  O OG  . SER B 1 244 ? -10.938 44.769  22.759  1.00 27.42  ? 244 SER B OG  1 
ATOM   5475  N N   . ALA B 1 245 ? -10.773 41.791  23.724  1.00 31.73  ? 245 ALA B N   1 
ATOM   5476  C CA  . ALA B 1 245 ? -11.024 41.036  24.947  1.00 31.98  ? 245 ALA B CA  1 
ATOM   5477  C C   . ALA B 1 245 ? -10.561 39.587  24.777  1.00 27.70  ? 245 ALA B C   1 
ATOM   5478  O O   . ALA B 1 245 ? -10.108 38.973  25.729  1.00 27.57  ? 245 ALA B O   1 
ATOM   5479  C CB  . ALA B 1 245 ? -12.488 41.130  25.337  1.00 35.02  ? 245 ALA B CB  1 
ATOM   5480  N N   . HIS B 1 246 ? -10.664 39.060  23.562  1.00 25.90  ? 246 HIS B N   1 
ATOM   5481  C CA  . HIS B 1 246 ? -10.238 37.704  23.253  1.00 29.06  ? 246 HIS B CA  1 
ATOM   5482  C C   . HIS B 1 246 ? -8.709  37.622  23.264  1.00 31.83  ? 246 HIS B C   1 
ATOM   5483  O O   . HIS B 1 246 ? -8.125  36.707  23.848  1.00 33.29  ? 246 HIS B O   1 
ATOM   5484  C CB  . HIS B 1 246 ? -10.861 37.272  21.919  1.00 27.04  ? 246 HIS B CB  1 
ATOM   5485  C CG  . HIS B 1 246 ? -10.536 35.891  21.493  1.00 26.33  ? 246 HIS B CG  1 
ATOM   5486  N ND1 . HIS B 1 246 ? -10.766 35.476  20.198  1.00 26.15  ? 246 HIS B ND1 1 
ATOM   5487  C CD2 . HIS B 1 246 ? -10.016 34.838  22.139  1.00 26.66  ? 246 HIS B CD2 1 
ATOM   5488  C CE1 . HIS B 1 246 ? -10.375 34.209  20.076  1.00 27.02  ? 246 HIS B CE1 1 
ATOM   5489  N NE2 . HIS B 1 246 ? -9.912  33.803  21.238  1.00 26.58  ? 246 HIS B NE2 1 
ATOM   5490  N N   . THR B 1 247 ? -8.064  38.606  22.636  1.00 29.82  ? 247 THR B N   1 
ATOM   5491  C CA  . THR B 1 247 ? -6.617  38.676  22.641  1.00 30.15  ? 247 THR B CA  1 
ATOM   5492  C C   . THR B 1 247 ? -6.095  38.557  24.076  1.00 30.46  ? 247 THR B C   1 
ATOM   5493  O O   . THR B 1 247 ? -5.267  37.676  24.352  1.00 27.31  ? 247 THR B O   1 
ATOM   5494  C CB  . THR B 1 247 ? -6.187  39.963  21.935  1.00 29.72  ? 247 THR B CB  1 
ATOM   5495  O OG1 . THR B 1 247 ? -6.443  39.653  20.574  1.00 24.98  ? 247 THR B OG1 1 
ATOM   5496  C CG2 . THR B 1 247 ? -4.702  40.241  22.031  1.00 31.79  ? 247 THR B CG2 1 
ATOM   5497  N N   . ASN B 1 248 ? -6.616  39.426  24.964  1.00 29.33  ? 248 ASN B N   1 
ATOM   5498  C CA  . ASN B 1 248 ? -6.262  39.484  26.381  1.00 29.44  ? 248 ASN B CA  1 
ATOM   5499  C C   . ASN B 1 248 ? -6.363  38.095  27.019  1.00 32.37  ? 248 ASN B C   1 
ATOM   5500  O O   . ASN B 1 248 ? -5.469  37.679  27.752  1.00 34.81  ? 248 ASN B O   1 
ATOM   5501  C CB  . ASN B 1 248 ? -7.160  40.480  27.107  1.00 29.33  ? 248 ASN B CB  1 
ATOM   5502  C CG  . ASN B 1 248 ? -6.872  40.638  28.584  1.00 28.38  ? 248 ASN B CG  1 
ATOM   5503  O OD1 . ASN B 1 248 ? -7.788  40.588  29.411  1.00 31.30  ? 248 ASN B OD1 1 
ATOM   5504  N ND2 . ASN B 1 248 ? -5.640  40.940  28.942  1.00 27.63  ? 248 ASN B ND2 1 
ATOM   5505  N N   . LEU B 1 249 ? -7.444  37.369  26.707  1.00 31.94  ? 249 LEU B N   1 
ATOM   5506  C CA  . LEU B 1 249 ? -7.716  36.069  27.300  1.00 30.23  ? 249 LEU B CA  1 
ATOM   5507  C C   . LEU B 1 249 ? -6.698  35.058  26.776  1.00 28.51  ? 249 LEU B C   1 
ATOM   5508  O O   . LEU B 1 249 ? -6.179  34.252  27.555  1.00 25.90  ? 249 LEU B O   1 
ATOM   5509  C CB  . LEU B 1 249 ? -9.140  35.581  27.010  1.00 28.49  ? 249 LEU B CB  1 
ATOM   5510  C CG  . LEU B 1 249 ? -10.290 36.145  27.849  1.00 30.60  ? 249 LEU B CG  1 
ATOM   5511  C CD1 . LEU B 1 249 ? -11.595 35.604  27.309  1.00 32.16  ? 249 LEU B CD1 1 
ATOM   5512  C CD2 . LEU B 1 249 ? -10.183 35.784  29.295  1.00 33.29  ? 249 LEU B CD2 1 
ATOM   5513  N N   . LEU B 1 250 ? -6.485  35.084  25.449  1.00 27.84  ? 250 LEU B N   1 
ATOM   5514  C CA  . LEU B 1 250 ? -5.605  34.152  24.765  1.00 26.67  ? 250 LEU B CA  1 
ATOM   5515  C C   . LEU B 1 250 ? -4.179  34.280  25.307  1.00 28.33  ? 250 LEU B C   1 
ATOM   5516  O O   . LEU B 1 250 ? -3.547  33.284  25.625  1.00 29.52  ? 250 LEU B O   1 
ATOM   5517  C CB  . LEU B 1 250 ? -5.676  34.410  23.264  1.00 27.41  ? 250 LEU B CB  1 
ATOM   5518  C CG  . LEU B 1 250 ? -4.736  33.577  22.384  1.00 25.65  ? 250 LEU B CG  1 
ATOM   5519  C CD1 . LEU B 1 250 ? -4.791  32.103  22.665  1.00 24.01  ? 250 LEU B CD1 1 
ATOM   5520  C CD2 . LEU B 1 250 ? -5.104  33.796  20.927  1.00 25.72  ? 250 LEU B CD2 1 
ATOM   5521  N N   . VAL B 1 251 ? -3.687  35.508  25.492  1.00 27.91  ? 251 VAL B N   1 
ATOM   5522  C CA  . VAL B 1 251 ? -2.315  35.686  25.925  1.00 27.46  ? 251 VAL B CA  1 
ATOM   5523  C C   . VAL B 1 251 ? -2.244  35.417  27.425  1.00 28.88  ? 251 VAL B C   1 
ATOM   5524  O O   . VAL B 1 251 ? -1.252  34.913  27.932  1.00 29.04  ? 251 VAL B O   1 
ATOM   5525  C CB  . VAL B 1 251 ? -1.833  37.082  25.484  1.00 27.55  ? 251 VAL B CB  1 
ATOM   5526  C CG1 . VAL B 1 251 ? -0.591  37.575  26.209  1.00 29.60  ? 251 VAL B CG1 1 
ATOM   5527  C CG2 . VAL B 1 251 ? -1.616  37.110  23.980  1.00 26.20  ? 251 VAL B CG2 1 
ATOM   5528  N N   . ASN B 1 252 ? -3.337  35.674  28.144  1.00 32.53  ? 252 ASN B N   1 
ATOM   5529  C CA  . ASN B 1 252 ? -3.349  35.457  29.587  1.00 30.30  ? 252 ASN B CA  1 
ATOM   5530  C C   . ASN B 1 252 ? -3.404  33.968  29.927  1.00 30.42  ? 252 ASN B C   1 
ATOM   5531  O O   . ASN B 1 252 ? -3.035  33.595  31.043  1.00 29.48  ? 252 ASN B O   1 
ATOM   5532  C CB  . ASN B 1 252 ? -4.490  36.212  30.255  1.00 30.73  ? 252 ASN B CB  1 
ATOM   5533  C CG  . ASN B 1 252 ? -4.728  35.741  31.666  1.00 32.90  ? 252 ASN B CG  1 
ATOM   5534  O OD1 . ASN B 1 252 ? -5.272  34.650  31.872  1.00 31.88  ? 252 ASN B OD1 1 
ATOM   5535  N ND2 . ASN B 1 252 ? -4.357  36.557  32.640  1.00 33.79  ? 252 ASN B ND2 1 
ATOM   5536  N N   . SER B 1 253 ? -3.874  33.143  28.974  1.00 30.20  ? 253 SER B N   1 
ATOM   5537  C CA  . SER B 1 253 ? -4.114  31.731  29.202  1.00 30.29  ? 253 SER B CA  1 
ATOM   5538  C C   . SER B 1 253 ? -2.787  30.986  29.193  1.00 32.10  ? 253 SER B C   1 
ATOM   5539  O O   . SER B 1 253 ? -2.742  29.793  29.492  1.00 29.95  ? 253 SER B O   1 
ATOM   5540  C CB  . SER B 1 253 ? -5.067  31.150  28.175  1.00 33.73  ? 253 SER B CB  1 
ATOM   5541  O OG  . SER B 1 253 ? -4.443  30.898  26.909  1.00 33.73  ? 253 SER B OG  1 
ATOM   5542  N N   . ALA B 1 254 ? -1.721  31.689  28.789  1.00 33.55  ? 254 ALA B N   1 
ATOM   5543  C CA  . ALA B 1 254 ? -0.399  31.086  28.730  1.00 34.93  ? 254 ALA B CA  1 
ATOM   5544  C C   . ALA B 1 254 ? 0.407   31.486  29.961  1.00 32.10  ? 254 ALA B C   1 
ATOM   5545  O O   . ALA B 1 254 ? 1.550   31.085  30.091  1.00 34.75  ? 254 ALA B O   1 
ATOM   5546  C CB  . ALA B 1 254 ? 0.283   31.507  27.451  1.00 33.67  ? 254 ALA B CB  1 
ATOM   5547  N N   . TYR B 1 255 ? -0.225  32.269  30.842  1.00 33.34  ? 255 TYR B N   1 
ATOM   5548  C CA  . TYR B 1 255 ? 0.321   32.783  32.092  1.00 33.40  ? 255 TYR B CA  1 
ATOM   5549  C C   . TYR B 1 255 ? 1.171   34.025  31.821  1.00 32.14  ? 255 TYR B C   1 
ATOM   5550  O O   . TYR B 1 255 ? 1.947   34.461  32.672  1.00 30.85  ? 255 TYR B O   1 
ATOM   5551  C CB  . TYR B 1 255 ? 1.070   31.762  32.960  1.00 35.66  ? 255 TYR B CB  1 
ATOM   5552  C CG  . TYR B 1 255 ? 0.269   30.614  33.569  1.00 35.30  ? 255 TYR B CG  1 
ATOM   5553  C CD1 . TYR B 1 255 ? -1.111  30.655  33.665  1.00 32.87  ? 255 TYR B CD1 1 
ATOM   5554  C CD2 . TYR B 1 255 ? 0.914   29.497  34.094  1.00 37.14  ? 255 TYR B CD2 1 
ATOM   5555  C CE1 . TYR B 1 255 ? -1.831  29.612  34.221  1.00 35.86  ? 255 TYR B CE1 1 
ATOM   5556  C CE2 . TYR B 1 255 ? 0.208   28.449  34.659  1.00 38.23  ? 255 TYR B CE2 1 
ATOM   5557  C CZ  . TYR B 1 255 ? -1.175  28.505  34.723  1.00 41.30  ? 255 TYR B CZ  1 
ATOM   5558  O OH  . TYR B 1 255 ? -1.911  27.501  35.292  1.00 41.78  ? 255 TYR B OH  1 
ATOM   5559  N N   . SER B 1 256 ? 0.947   34.683  30.684  1.00 29.99  ? 256 SER B N   1 
ATOM   5560  C CA  . SER B 1 256 ? 1.522   36.005  30.496  1.00 28.89  ? 256 SER B CA  1 
ATOM   5561  C C   . SER B 1 256 ? 0.768   36.995  31.363  1.00 27.41  ? 256 SER B C   1 
ATOM   5562  O O   . SER B 1 256 ? -0.451  36.943  31.426  1.00 31.00  ? 256 SER B O   1 
ATOM   5563  C CB  . SER B 1 256 ? 1.472   36.432  29.063  1.00 29.19  ? 256 SER B CB  1 
ATOM   5564  O OG  . SER B 1 256 ? 2.271   35.571  28.271  1.00 31.68  ? 256 SER B OG  1 
ATOM   5565  N N   . ASP B 1 257 ? 1.495   37.907  31.996  1.00 27.15  ? 257 ASP B N   1 
ATOM   5566  C CA  . ASP B 1 257 ? 0.910   38.870  32.905  1.00 27.43  ? 257 ASP B CA  1 
ATOM   5567  C C   . ASP B 1 257 ? 0.088   39.897  32.132  1.00 28.02  ? 257 ASP B C   1 
ATOM   5568  O O   . ASP B 1 257 ? 0.101   39.894  30.916  1.00 27.82  ? 257 ASP B O   1 
ATOM   5569  C CB  . ASP B 1 257 ? 2.008   39.557  33.683  1.00 28.34  ? 257 ASP B CB  1 
ATOM   5570  C CG  . ASP B 1 257 ? 2.973   40.370  32.840  1.00 29.76  ? 257 ASP B CG  1 
ATOM   5571  O OD1 . ASP B 1 257 ? 2.560   41.445  32.312  1.00 31.27  ? 257 ASP B OD1 1 
ATOM   5572  O OD2 . ASP B 1 257 ? 4.131   39.939  32.764  1.00 27.69  ? 257 ASP B OD2 1 
ATOM   5573  N N   . ILE B 1 258 ? -0.552  40.826  32.852  1.00 28.19  ? 258 ILE B N   1 
ATOM   5574  C CA  . ILE B 1 258 ? -1.540  41.739  32.296  1.00 27.82  ? 258 ILE B CA  1 
ATOM   5575  C C   . ILE B 1 258 ? -0.921  42.820  31.398  1.00 27.59  ? 258 ILE B C   1 
ATOM   5576  O O   . ILE B 1 258 ? -1.615  43.367  30.538  1.00 24.00  ? 258 ILE B O   1 
ATOM   5577  C CB  . ILE B 1 258 ? -2.342  42.396  33.432  1.00 29.32  ? 258 ILE B CB  1 
ATOM   5578  C CG1 . ILE B 1 258 ? -3.622  43.087  32.913  1.00 30.60  ? 258 ILE B CG1 1 
ATOM   5579  C CG2 . ILE B 1 258 ? -1.472  43.374  34.222  1.00 28.29  ? 258 ILE B CG2 1 
ATOM   5580  C CD1 . ILE B 1 258 ? -4.655  42.137  32.351  1.00 29.42  ? 258 ILE B CD1 1 
ATOM   5581  N N   . TYR B 1 259 ? 0.348   43.190  31.624  1.00 27.77  ? 259 TYR B N   1 
ATOM   5582  C CA  . TYR B 1 259 ? 1.010   44.170  30.763  1.00 24.22  ? 259 TYR B CA  1 
ATOM   5583  C C   . TYR B 1 259 ? 1.188   43.563  29.369  1.00 26.03  ? 259 TYR B C   1 
ATOM   5584  O O   . TYR B 1 259 ? 1.021   44.235  28.350  1.00 25.62  ? 259 TYR B O   1 
ATOM   5585  C CB  . TYR B 1 259 ? 2.335   44.617  31.391  1.00 22.86  ? 259 TYR B CB  1 
ATOM   5586  C CG  . TYR B 1 259 ? 2.208   45.317  32.729  1.00 21.52  ? 259 TYR B CG  1 
ATOM   5587  C CD1 . TYR B 1 259 ? 2.027   46.686  32.805  1.00 21.90  ? 259 TYR B CD1 1 
ATOM   5588  C CD2 . TYR B 1 259 ? 2.271   44.612  33.928  1.00 23.66  ? 259 TYR B CD2 1 
ATOM   5589  C CE1 . TYR B 1 259 ? 1.922   47.341  34.024  1.00 22.36  ? 259 TYR B CE1 1 
ATOM   5590  C CE2 . TYR B 1 259 ? 2.169   45.254  35.159  1.00 21.03  ? 259 TYR B CE2 1 
ATOM   5591  C CZ  . TYR B 1 259 ? 1.994   46.626  35.208  1.00 21.18  ? 259 TYR B CZ  1 
ATOM   5592  O OH  . TYR B 1 259 ? 1.874   47.287  36.405  1.00 23.17  ? 259 TYR B OH  1 
ATOM   5593  N N   . ARG B 1 260 ? 1.511   42.266  29.347  1.00 25.57  ? 260 ARG B N   1 
ATOM   5594  C CA  . ARG B 1 260 ? 1.634   41.514  28.116  1.00 26.56  ? 260 ARG B CA  1 
ATOM   5595  C C   . ARG B 1 260 ? 0.288   41.233  27.450  1.00 25.76  ? 260 ARG B C   1 
ATOM   5596  O O   . ARG B 1 260 ? 0.196   41.307  26.224  1.00 28.75  ? 260 ARG B O   1 
ATOM   5597  C CB  . ARG B 1 260 ? 2.395   40.216  28.414  1.00 29.09  ? 260 ARG B CB  1 
ATOM   5598  C CG  . ARG B 1 260 ? 3.893   40.454  28.506  1.00 32.89  ? 260 ARG B CG  1 
ATOM   5599  C CD  . ARG B 1 260 ? 4.713   39.208  28.782  1.00 35.39  ? 260 ARG B CD  1 
ATOM   5600  N NE  . ARG B 1 260 ? 6.145   39.486  28.618  1.00 36.74  ? 260 ARG B NE  1 
ATOM   5601  C CZ  . ARG B 1 260 ? 7.134   38.841  29.240  1.00 37.90  ? 260 ARG B CZ  1 
ATOM   5602  N NH1 . ARG B 1 260 ? 8.390   39.214  29.069  1.00 37.39  ? 260 ARG B NH1 1 
ATOM   5603  N NH2 . ARG B 1 260 ? 6.870   37.850  30.066  1.00 36.23  ? 260 ARG B NH2 1 
ATOM   5604  N N   . SER B 1 261 ? -0.730  40.813  28.213  1.00 26.37  ? 261 SER B N   1 
ATOM   5605  C CA  . SER B 1 261 ? -2.016  40.461  27.599  1.00 27.28  ? 261 SER B CA  1 
ATOM   5606  C C   . SER B 1 261 ? -2.782  41.715  27.197  1.00 24.13  ? 261 SER B C   1 
ATOM   5607  O O   . SER B 1 261 ? -3.333  41.758  26.121  1.00 28.12  ? 261 SER B O   1 
ATOM   5608  C CB  . SER B 1 261 ? -2.900  39.552  28.447  1.00 26.83  ? 261 SER B CB  1 
ATOM   5609  O OG  . SER B 1 261 ? -3.251  40.126  29.699  1.00 24.72  ? 261 SER B OG  1 
ATOM   5610  N N   . PHE B 1 262 ? -2.795  42.755  28.025  1.00 24.53  ? 262 PHE B N   1 
ATOM   5611  C CA  . PHE B 1 262 ? -3.554  43.942  27.679  1.00 24.45  ? 262 PHE B CA  1 
ATOM   5612  C C   . PHE B 1 262 ? -2.872  44.704  26.546  1.00 24.80  ? 262 PHE B C   1 
ATOM   5613  O O   . PHE B 1 262 ? -3.585  45.269  25.712  1.00 24.32  ? 262 PHE B O   1 
ATOM   5614  C CB  . PHE B 1 262 ? -3.836  44.873  28.859  1.00 26.24  ? 262 PHE B CB  1 
ATOM   5615  C CG  . PHE B 1 262 ? -4.798  45.990  28.490  1.00 29.25  ? 262 PHE B CG  1 
ATOM   5616  C CD1 . PHE B 1 262 ? -6.158  45.718  28.287  1.00 28.72  ? 262 PHE B CD1 1 
ATOM   5617  C CD2 . PHE B 1 262 ? -4.343  47.299  28.304  1.00 30.51  ? 262 PHE B CD2 1 
ATOM   5618  C CE1 . PHE B 1 262 ? -7.031  46.725  27.918  1.00 26.24  ? 262 PHE B CE1 1 
ATOM   5619  C CE2 . PHE B 1 262 ? -5.231  48.307  27.935  1.00 29.77  ? 262 PHE B CE2 1 
ATOM   5620  C CZ  . PHE B 1 262 ? -6.567  48.016  27.744  1.00 28.21  ? 262 PHE B CZ  1 
ATOM   5621  N N   . SER B 1 263 ? -1.520  44.754  26.502  1.00 26.89  ? 263 SER B N   1 
ATOM   5622  C CA  . SER B 1 263 ? -0.834  45.466  25.415  1.00 24.31  ? 263 SER B CA  1 
ATOM   5623  C C   . SER B 1 263 ? -1.071  44.751  24.089  1.00 23.57  ? 263 SER B C   1 
ATOM   5624  O O   . SER B 1 263 ? -1.312  45.387  23.084  1.00 24.04  ? 263 SER B O   1 
ATOM   5625  C CB  . SER B 1 263 ? 0.634   45.659  25.646  1.00 24.27  ? 263 SER B CB  1 
ATOM   5626  O OG  . SER B 1 263 ? 1.280   44.394  25.682  1.00 25.33  ? 263 SER B OG  1 
ATOM   5627  N N   . ALA B 1 264 ? -1.040  43.423  24.088  1.00 24.44  ? 264 ALA B N   1 
ATOM   5628  C CA  . ALA B 1 264 ? -1.488  42.657  22.931  1.00 25.52  ? 264 ALA B CA  1 
ATOM   5629  C C   . ALA B 1 264 ? -2.916  43.028  22.519  1.00 25.35  ? 264 ALA B C   1 
ATOM   5630  O O   . ALA B 1 264 ? -3.215  43.178  21.338  1.00 25.10  ? 264 ALA B O   1 
ATOM   5631  C CB  . ALA B 1 264 ? -1.393  41.167  23.237  1.00 25.22  ? 264 ALA B CB  1 
ATOM   5632  N N   . ALA B 1 265 ? -3.830  43.100  23.485  1.00 26.90  ? 265 ALA B N   1 
ATOM   5633  C CA  . ALA B 1 265 ? -5.218  43.438  23.177  1.00 29.13  ? 265 ALA B CA  1 
ATOM   5634  C C   . ALA B 1 265 ? -5.303  44.789  22.459  1.00 28.61  ? 265 ALA B C   1 
ATOM   5635  O O   . ALA B 1 265 ? -6.115  44.978  21.545  1.00 26.25  ? 265 ALA B O   1 
ATOM   5636  C CB  . ALA B 1 265 ? -6.050  43.461  24.447  1.00 29.91  ? 265 ALA B CB  1 
ATOM   5637  N N   . MET B 1 266 ? -4.482  45.746  22.904  1.00 26.89  ? 266 MET B N   1 
ATOM   5638  C CA  . MET B 1 266 ? -4.509  47.067  22.313  1.00 26.16  ? 266 MET B CA  1 
ATOM   5639  C C   . MET B 1 266 ? -4.021  46.955  20.872  1.00 26.60  ? 266 MET B C   1 
ATOM   5640  O O   . MET B 1 266 ? -4.509  47.673  20.014  1.00 25.04  ? 266 MET B O   1 
ATOM   5641  C CB  . MET B 1 266 ? -3.690  48.035  23.170  1.00 27.00  ? 266 MET B CB  1 
ATOM   5642  C CG  . MET B 1 266 ? -4.325  48.338  24.514  1.00 27.90  ? 266 MET B CG  1 
ATOM   5643  S SD  . MET B 1 266 ? -5.963  49.099  24.401  1.00 27.99  ? 266 MET B SD  1 
ATOM   5644  C CE  . MET B 1 266 ? -6.993  47.626  24.343  1.00 24.00  ? 266 MET B CE  1 
ATOM   5645  N N   . ASN B 1 267 ? -3.067  46.051  20.607  1.00 25.52  ? 267 ASN B N   1 
ATOM   5646  C CA  . ASN B 1 267 ? -2.606  45.856  19.245  1.00 27.21  ? 267 ASN B CA  1 
ATOM   5647  C C   . ASN B 1 267 ? -3.794  45.437  18.365  1.00 27.86  ? 267 ASN B C   1 
ATOM   5648  O O   . ASN B 1 267 ? -3.900  45.829  17.206  1.00 29.85  ? 267 ASN B O   1 
ATOM   5649  C CB  . ASN B 1 267 ? -1.408  44.907  19.181  1.00 25.82  ? 267 ASN B CB  1 
ATOM   5650  C CG  . ASN B 1 267 ? -0.104  45.562  19.592  1.00 26.21  ? 267 ASN B CG  1 
ATOM   5651  O OD1 . ASN B 1 267 ? -0.126  46.723  20.016  1.00 28.45  ? 267 ASN B OD1 1 
ATOM   5652  N ND2 . ASN B 1 267 ? 1.028   44.857  19.502  1.00 23.07  ? 267 ASN B ND2 1 
ATOM   5653  N N   . GLY B 1 268 ? -4.697  44.634  18.922  1.00 29.59  ? 268 GLY B N   1 
ATOM   5654  C CA  . GLY B 1 268 ? -5.882  44.161  18.206  1.00 29.74  ? 268 GLY B CA  1 
ATOM   5655  C C   . GLY B 1 268 ? -6.952  45.242  18.063  1.00 26.83  ? 268 GLY B C   1 
ATOM   5656  O O   . GLY B 1 268 ? -7.562  45.350  17.015  1.00 27.96  ? 268 GLY B O   1 
ATOM   5657  N N   . LEU B 1 269 ? -7.143  46.051  19.112  1.00 27.92  ? 269 LEU B N   1 
ATOM   5658  C CA  . LEU B 1 269 ? -8.029  47.203  19.095  1.00 29.24  ? 269 LEU B CA  1 
ATOM   5659  C C   . LEU B 1 269 ? -7.556  48.264  18.095  1.00 32.08  ? 269 LEU B C   1 
ATOM   5660  O O   . LEU B 1 269 ? -8.355  49.026  17.556  1.00 32.64  ? 269 LEU B O   1 
ATOM   5661  C CB  . LEU B 1 269 ? -8.138  47.805  20.494  1.00 27.93  ? 269 LEU B CB  1 
ATOM   5662  C CG  . LEU B 1 269 ? -9.149  48.948  20.623  1.00 30.77  ? 269 LEU B CG  1 
ATOM   5663  C CD1 . LEU B 1 269 ? -10.531 48.386  20.355  1.00 32.19  ? 269 LEU B CD1 1 
ATOM   5664  C CD2 . LEU B 1 269 ? -9.142  49.704  21.952  1.00 31.56  ? 269 LEU B CD2 1 
ATOM   5665  N N   . ALA B 1 270 ? -6.247  48.359  17.868  1.00 33.85  ? 270 ALA B N   1 
ATOM   5666  C CA  . ALA B 1 270 ? -5.721  49.294  16.885  1.00 34.17  ? 270 ALA B CA  1 
ATOM   5667  C C   . ALA B 1 270 ? -6.139  48.908  15.462  1.00 29.44  ? 270 ALA B C   1 
ATOM   5668  O O   . ALA B 1 270 ? -6.094  49.731  14.570  1.00 28.93  ? 270 ALA B O   1 
ATOM   5669  C CB  . ALA B 1 270 ? -4.219  49.350  17.030  1.00 37.82  ? 270 ALA B CB  1 
ATOM   5670  N N   . GLY B 1 271 ? -6.536  47.655  15.236  1.00 28.94  ? 271 GLY B N   1 
ATOM   5671  C CA  . GLY B 1 271 ? -6.930  47.197  13.914  1.00 28.05  ? 271 GLY B CA  1 
ATOM   5672  C C   . GLY B 1 271 ? -8.104  48.002  13.361  1.00 30.40  ? 271 GLY B C   1 
ATOM   5673  O O   . GLY B 1 271 ? -9.062  48.274  14.079  1.00 26.76  ? 271 GLY B O   1 
ATOM   5674  N N   . PRO B 1 272 ? -8.061  48.439  12.081  1.00 32.59  ? 272 PRO B N   1 
ATOM   5675  C CA  . PRO B 1 272 ? -9.144  49.250  11.521  1.00 34.13  ? 272 PRO B CA  1 
ATOM   5676  C C   . PRO B 1 272 ? -10.557 48.663  11.532  1.00 39.09  ? 272 PRO B C   1 
ATOM   5677  O O   . PRO B 1 272 ? -11.525 49.419  11.384  1.00 41.47  ? 272 PRO B O   1 
ATOM   5678  C CB  . PRO B 1 272 ? -8.657  49.465  10.095  1.00 34.26  ? 272 PRO B CB  1 
ATOM   5679  C CG  . PRO B 1 272 ? -7.162  49.369  10.199  1.00 32.72  ? 272 PRO B CG  1 
ATOM   5680  C CD  . PRO B 1 272 ? -6.940  48.236  11.149  1.00 31.39  ? 272 PRO B CD  1 
ATOM   5681  N N   . LEU B 1 273 ? -10.665 47.330  11.709  1.00 39.42  ? 273 LEU B N   1 
ATOM   5682  C CA  . LEU B 1 273 ? -11.955 46.650  11.816  1.00 39.85  ? 273 LEU B CA  1 
ATOM   5683  C C   . LEU B 1 273 ? -12.486 46.567  13.252  1.00 39.86  ? 273 LEU B C   1 
ATOM   5684  O O   . LEU B 1 273 ? -13.569 46.038  13.459  1.00 46.53  ? 273 LEU B O   1 
ATOM   5685  C CB  . LEU B 1 273 ? -11.865 45.243  11.215  1.00 41.05  ? 273 LEU B CB  1 
ATOM   5686  C CG  . LEU B 1 273 ? -11.672 45.136  9.692   1.00 38.22  ? 273 LEU B CG  1 
ATOM   5687  C CD1 . LEU B 1 273 ? -11.858 43.693  9.257   1.00 37.02  ? 273 LEU B CD1 1 
ATOM   5688  C CD2 . LEU B 1 273 ? -12.620 46.021  8.905   1.00 35.85  ? 273 LEU B CD2 1 
ATOM   5689  N N   . HIS B 1 274 ? -11.758 47.071  14.252  1.00 36.62  ? 274 HIS B N   1 
ATOM   5690  C CA  . HIS B 1 274 ? -12.153 46.872  15.638  1.00 35.57  ? 274 HIS B CA  1 
ATOM   5691  C C   . HIS B 1 274 ? -12.316 48.195  16.390  1.00 30.63  ? 274 HIS B C   1 
ATOM   5692  O O   . HIS B 1 274 ? -13.102 48.265  17.339  1.00 29.70  ? 274 HIS B O   1 
ATOM   5693  C CB  . HIS B 1 274 ? -11.205 45.882  16.343  1.00 38.52  ? 274 HIS B CB  1 
ATOM   5694  C CG  . HIS B 1 274 ? -11.577 45.530  17.760  1.00 37.25  ? 274 HIS B CG  1 
ATOM   5695  N ND1 . HIS B 1 274 ? -12.844 45.712  18.277  1.00 34.23  ? 274 HIS B ND1 1 
ATOM   5696  C CD2 . HIS B 1 274 ? -10.841 45.015  18.761  1.00 37.46  ? 274 HIS B CD2 1 
ATOM   5697  C CE1 . HIS B 1 274 ? -12.865 45.325  19.547  1.00 37.51  ? 274 HIS B CE1 1 
ATOM   5698  N NE2 . HIS B 1 274 ? -11.664 44.897  19.866  1.00 38.97  ? 274 HIS B NE2 1 
ATOM   5699  N N   . GLY B 1 275 ? -11.597 49.243  15.980  1.00 28.41  ? 275 GLY B N   1 
ATOM   5700  C CA  . GLY B 1 275 ? -11.382 50.360  16.885  1.00 29.53  ? 275 GLY B CA  1 
ATOM   5701  C C   . GLY B 1 275 ? -11.681 51.740  16.304  1.00 30.74  ? 275 GLY B C   1 
ATOM   5702  O O   . GLY B 1 275 ? -11.510 52.719  17.043  1.00 30.40  ? 275 GLY B O   1 
ATOM   5703  N N   . LEU B 1 276 ? -12.160 51.807  15.044  1.00 28.83  ? 276 LEU B N   1 
ATOM   5704  C CA  . LEU B 1 276 ? -12.343 53.083  14.356  1.00 32.56  ? 276 LEU B CA  1 
ATOM   5705  C C   . LEU B 1 276 ? -13.811 53.555  14.283  1.00 35.24  ? 276 LEU B C   1 
ATOM   5706  O O   . LEU B 1 276 ? -14.066 54.703  13.930  1.00 31.28  ? 276 LEU B O   1 
ATOM   5707  C CB  . LEU B 1 276 ? -11.771 52.953  12.940  1.00 31.93  ? 276 LEU B CB  1 
ATOM   5708  C CG  . LEU B 1 276 ? -10.260 52.711  12.813  1.00 32.55  ? 276 LEU B CG  1 
ATOM   5709  C CD1 . LEU B 1 276 ? -9.872  52.718  11.354  1.00 32.74  ? 276 LEU B CD1 1 
ATOM   5710  C CD2 . LEU B 1 276 ? -9.400  53.700  13.561  1.00 31.28  ? 276 LEU B CD2 1 
ATOM   5711  N N   . ALA B 1 277 ? -14.796 52.682  14.559  1.00 37.28  ? 277 ALA B N   1 
ATOM   5712  C CA  . ALA B 1 277 ? -16.179 52.924  14.144  1.00 31.74  ? 277 ALA B CA  1 
ATOM   5713  C C   . ALA B 1 277 ? -16.690 54.292  14.609  1.00 31.62  ? 277 ALA B C   1 
ATOM   5714  O O   . ALA B 1 277 ? -17.199 55.066  13.815  1.00 33.16  ? 277 ALA B O   1 
ATOM   5715  C CB  . ALA B 1 277 ? -17.050 51.792  14.609  1.00 28.53  ? 277 ALA B CB  1 
ATOM   5716  N N   . ASN B 1 278 ? -16.458 54.638  15.873  1.00 34.15  ? 278 ASN B N   1 
ATOM   5717  C CA  . ASN B 1 278 ? -16.912 55.898  16.447  1.00 35.79  ? 278 ASN B CA  1 
ATOM   5718  C C   . ASN B 1 278 ? -16.436 57.106  15.620  1.00 33.99  ? 278 ASN B C   1 
ATOM   5719  O O   . ASN B 1 278 ? -17.114 58.139  15.577  1.00 32.64  ? 278 ASN B O   1 
ATOM   5720  C CB  . ASN B 1 278 ? -16.640 55.822  17.947  1.00 38.09  ? 278 ASN B CB  1 
ATOM   5721  C CG  . ASN B 1 278 ? -15.766 56.904  18.508  1.00 37.61  ? 278 ASN B CG  1 
ATOM   5722  O OD1 . ASN B 1 278 ? -16.131 58.075  18.503  1.00 47.33  ? 278 ASN B OD1 1 
ATOM   5723  N ND2 . ASN B 1 278 ? -14.663 56.507  19.096  1.00 41.99  ? 278 ASN B ND2 1 
ATOM   5724  N N   . GLN B 1 279 ? -15.289 56.951  14.952  1.00 33.39  ? 279 GLN B N   1 
ATOM   5725  C CA  . GLN B 1 279 ? -14.661 57.984  14.144  1.00 34.50  ? 279 GLN B CA  1 
ATOM   5726  C C   . GLN B 1 279 ? -15.333 58.038  12.779  1.00 32.34  ? 279 GLN B C   1 
ATOM   5727  O O   . GLN B 1 279 ? -15.551 59.117  12.220  1.00 27.82  ? 279 GLN B O   1 
ATOM   5728  C CB  . GLN B 1 279 ? -13.185 57.691  13.847  1.00 33.02  ? 279 GLN B CB  1 
ATOM   5729  C CG  . GLN B 1 279 ? -12.281 57.798  15.064  1.00 36.06  ? 279 GLN B CG  1 
ATOM   5730  C CD  . GLN B 1 279 ? -10.893 57.211  14.875  1.00 41.00  ? 279 GLN B CD  1 
ATOM   5731  O OE1 . GLN B 1 279 ? -10.191 57.475  13.879  1.00 43.01  ? 279 GLN B OE1 1 
ATOM   5732  N NE2 . GLN B 1 279 ? -10.470 56.432  15.869  1.00 42.37  ? 279 GLN B NE2 1 
ATOM   5733  N N   . GLU B 1 280 ? -15.588 56.844  12.242  1.00 30.55  ? 280 GLU B N   1 
ATOM   5734  C CA  . GLU B 1 280 ? -16.248 56.726  10.960  1.00 37.25  ? 280 GLU B CA  1 
ATOM   5735  C C   . GLU B 1 280 ? -17.612 57.412  11.041  1.00 34.42  ? 280 GLU B C   1 
ATOM   5736  O O   . GLU B 1 280 ? -18.054 58.049  10.090  1.00 31.99  ? 280 GLU B O   1 
ATOM   5737  C CB  . GLU B 1 280 ? -16.249 55.259  10.531  1.00 40.76  ? 280 GLU B CB  1 
ATOM   5738  C CG  . GLU B 1 280 ? -14.939 54.886  9.846   1.00 48.62  ? 280 GLU B CG  1 
ATOM   5739  C CD  . GLU B 1 280 ? -14.470 53.449  9.942   1.00 55.33  ? 280 GLU B CD  1 
ATOM   5740  O OE1 . GLU B 1 280 ? -13.332 53.214  9.450   1.00 59.40  ? 280 GLU B OE1 1 
ATOM   5741  O OE2 . GLU B 1 280 ? -15.206 52.586  10.480  1.00 56.89  ? 280 GLU B OE2 1 
ATOM   5742  N N   . VAL B 1 281 ? -18.244 57.306  12.203  1.00 30.33  ? 281 VAL B N   1 
ATOM   5743  C CA  . VAL B 1 281 ? -19.539 57.903  12.409  1.00 32.74  ? 281 VAL B CA  1 
ATOM   5744  C C   . VAL B 1 281 ? -19.390 59.418  12.459  1.00 32.89  ? 281 VAL B C   1 
ATOM   5745  O O   . VAL B 1 281 ? -20.066 60.130  11.717  1.00 32.86  ? 281 VAL B O   1 
ATOM   5746  C CB  . VAL B 1 281 ? -20.219 57.323  13.664  1.00 31.68  ? 281 VAL B CB  1 
ATOM   5747  C CG1 . VAL B 1 281 ? -21.453 58.128  14.070  1.00 28.74  ? 281 VAL B CG1 1 
ATOM   5748  C CG2 . VAL B 1 281 ? -20.590 55.856  13.429  1.00 30.88  ? 281 VAL B CG2 1 
ATOM   5749  N N   . LEU B 1 282 ? -18.518 59.914  13.331  1.00 33.15  ? 282 LEU B N   1 
ATOM   5750  C CA  . LEU B 1 282 ? -18.405 61.358  13.498  1.00 32.79  ? 282 LEU B CA  1 
ATOM   5751  C C   . LEU B 1 282 ? -18.160 62.029  12.131  1.00 29.91  ? 282 LEU B C   1 
ATOM   5752  O O   . LEU B 1 282 ? -18.820 63.014  11.795  1.00 25.18  ? 282 LEU B O   1 
ATOM   5753  C CB  . LEU B 1 282 ? -17.332 61.670  14.549  1.00 29.13  ? 282 LEU B CB  1 
ATOM   5754  C CG  . LEU B 1 282 ? -17.014 63.152  14.768  1.00 31.03  ? 282 LEU B CG  1 
ATOM   5755  C CD1 . LEU B 1 282 ? -18.216 63.940  15.239  1.00 30.47  ? 282 LEU B CD1 1 
ATOM   5756  C CD2 . LEU B 1 282 ? -15.887 63.333  15.746  1.00 33.70  ? 282 LEU B CD2 1 
ATOM   5757  N N   . ARG B 1 283 ? -17.225 61.474  11.343  1.00 33.09  ? 283 ARG B N   1 
ATOM   5758  C CA  . ARG B 1 283 ? -16.872 61.985  10.016  1.00 37.49  ? 283 ARG B CA  1 
ATOM   5759  C C   . ARG B 1 283 ? -18.101 62.037  9.105   1.00 35.51  ? 283 ARG B C   1 
ATOM   5760  O O   . ARG B 1 283 ? -18.311 63.033  8.413   1.00 39.50  ? 283 ARG B O   1 
ATOM   5761  C CB  . ARG B 1 283 ? -15.783 61.152  9.320   1.00 37.93  ? 283 ARG B CB  1 
ATOM   5762  C CG  . ARG B 1 283 ? -14.362 61.394  9.811   1.00 37.52  ? 283 ARG B CG  1 
ATOM   5763  C CD  . ARG B 1 283 ? -13.448 60.224  9.409   1.00 42.58  ? 283 ARG B CD  1 
ATOM   5764  N NE  . ARG B 1 283 ? -12.189 60.115  10.161  1.00 40.57  ? 283 ARG B NE  1 
ATOM   5765  C CZ  . ARG B 1 283 ? -11.211 61.026  10.197  1.00 41.35  ? 283 ARG B CZ  1 
ATOM   5766  N NH1 . ARG B 1 283 ? -11.331 62.229  9.644   1.00 36.99  ? 283 ARG B NH1 1 
ATOM   5767  N NH2 . ARG B 1 283 ? -10.101 60.721  10.840  1.00 40.70  ? 283 ARG B NH2 1 
ATOM   5768  N N   . TRP B 1 284 ? -18.897 60.960  9.125   1.00 35.16  ? 284 TRP B N   1 
ATOM   5769  C CA  . TRP B 1 284 ? -20.175 60.865  8.429   1.00 32.86  ? 284 TRP B CA  1 
ATOM   5770  C C   . TRP B 1 284 ? -21.176 61.932  8.879   1.00 35.16  ? 284 TRP B C   1 
ATOM   5771  O O   . TRP B 1 284 ? -21.790 62.596  8.050   1.00 35.29  ? 284 TRP B O   1 
ATOM   5772  C CB  . TRP B 1 284 ? -20.754 59.472  8.653   1.00 30.90  ? 284 TRP B CB  1 
ATOM   5773  C CG  . TRP B 1 284 ? -21.925 59.144  7.769   1.00 33.16  ? 284 TRP B CG  1 
ATOM   5774  C CD1 . TRP B 1 284 ? -21.894 58.708  6.473   1.00 31.22  ? 284 TRP B CD1 1 
ATOM   5775  C CD2 . TRP B 1 284 ? -23.310 59.146  8.175   1.00 37.65  ? 284 TRP B CD2 1 
ATOM   5776  N NE1 . TRP B 1 284 ? -23.169 58.492  6.029   1.00 35.17  ? 284 TRP B NE1 1 
ATOM   5777  C CE2 . TRP B 1 284 ? -24.059 58.729  7.048   1.00 38.13  ? 284 TRP B CE2 1 
ATOM   5778  C CE3 . TRP B 1 284 ? -23.984 59.459  9.366   1.00 35.04  ? 284 TRP B CE3 1 
ATOM   5779  C CZ2 . TRP B 1 284 ? -25.453 58.620  7.088   1.00 39.66  ? 284 TRP B CZ2 1 
ATOM   5780  C CZ3 . TRP B 1 284 ? -25.357 59.342  9.396   1.00 36.25  ? 284 TRP B CZ3 1 
ATOM   5781  C CH2 . TRP B 1 284 ? -26.082 58.921  8.276   1.00 35.85  ? 284 TRP B CH2 1 
ATOM   5782  N N   . ILE B 1 285 ? -21.346 62.113  10.191  1.00 31.77  ? 285 ILE B N   1 
ATOM   5783  C CA  . ILE B 1 285 ? -22.170 63.206  10.670  1.00 32.21  ? 285 ILE B CA  1 
ATOM   5784  C C   . ILE B 1 285 ? -21.643 64.529  10.107  1.00 32.00  ? 285 ILE B C   1 
ATOM   5785  O O   . ILE B 1 285 ? -22.438 65.398  9.725   1.00 23.23  ? 285 ILE B O   1 
ATOM   5786  C CB  . ILE B 1 285 ? -22.259 63.220  12.210  1.00 34.53  ? 285 ILE B CB  1 
ATOM   5787  C CG1 . ILE B 1 285 ? -22.911 61.953  12.739  1.00 33.71  ? 285 ILE B CG1 1 
ATOM   5788  C CG2 . ILE B 1 285 ? -22.991 64.466  12.721  1.00 35.27  ? 285 ILE B CG2 1 
ATOM   5789  C CD1 . ILE B 1 285 ? -24.379 61.826  12.380  1.00 37.30  ? 285 ILE B CD1 1 
ATOM   5790  N N   . GLN B 1 286 ? -20.306 64.684  10.073  1.00 35.15  ? 286 GLN B N   1 
ATOM   5791  C CA  . GLN B 1 286 ? -19.693 65.944  9.653   1.00 34.24  ? 286 GLN B CA  1 
ATOM   5792  C C   . GLN B 1 286 ? -19.875 66.135  8.150   1.00 32.47  ? 286 GLN B C   1 
ATOM   5793  O O   . GLN B 1 286 ? -20.160 67.243  7.710   1.00 33.57  ? 286 GLN B O   1 
ATOM   5794  C CB  . GLN B 1 286 ? -18.237 66.075  10.108  1.00 33.12  ? 286 GLN B CB  1 
ATOM   5795  C CG  . GLN B 1 286 ? -18.091 66.310  11.610  1.00 30.98  ? 286 GLN B CG  1 
ATOM   5796  C CD  . GLN B 1 286 ? -16.695 66.045  12.130  1.00 30.63  ? 286 GLN B CD  1 
ATOM   5797  O OE1 . GLN B 1 286 ? -16.119 66.837  12.881  1.00 31.82  ? 286 GLN B OE1 1 
ATOM   5798  N NE2 . GLN B 1 286 ? -16.151 64.897  11.767  1.00 26.93  ? 286 GLN B NE2 1 
ATOM   5799  N N   . MET B 1 287 ? -19.781 65.042  7.381   1.00 32.89  ? 287 MET B N   1 
ATOM   5800  C CA  . MET B 1 287 ? -20.032 65.086  5.943   1.00 32.37  ? 287 MET B CA  1 
ATOM   5801  C C   . MET B 1 287 ? -21.462 65.571  5.686   1.00 35.38  ? 287 MET B C   1 
ATOM   5802  O O   . MET B 1 287 ? -21.672 66.381  4.790   1.00 44.61  ? 287 MET B O   1 
ATOM   5803  C CB  . MET B 1 287 ? -19.752 63.713  5.305   1.00 31.00  ? 287 MET B CB  1 
ATOM   5804  C CG  . MET B 1 287 ? -20.191 63.525  3.853   1.00 31.06  ? 287 MET B CG  1 
ATOM   5805  S SD  . MET B 1 287 ? -21.954 63.184  3.613   1.00 36.48  ? 287 MET B SD  1 
ATOM   5806  C CE  . MET B 1 287 ? -22.292 61.628  4.442   1.00 34.53  ? 287 MET B CE  1 
ATOM   5807  N N   . LEU B 1 288 ? -22.433 65.081  6.480   1.00 35.19  ? 288 LEU B N   1 
ATOM   5808  C CA  . LEU B 1 288 ? -23.837 65.449  6.341   1.00 33.46  ? 288 LEU B CA  1 
ATOM   5809  C C   . LEU B 1 288 ? -24.000 66.942  6.559   1.00 31.78  ? 288 LEU B C   1 
ATOM   5810  O O   . LEU B 1 288 ? -24.641 67.597  5.760   1.00 29.02  ? 288 LEU B O   1 
ATOM   5811  C CB  . LEU B 1 288 ? -24.729 64.656  7.295   1.00 34.64  ? 288 LEU B CB  1 
ATOM   5812  C CG  . LEU B 1 288 ? -24.959 63.190  6.906   1.00 38.56  ? 288 LEU B CG  1 
ATOM   5813  C CD1 . LEU B 1 288 ? -25.634 62.330  7.997   1.00 37.36  ? 288 LEU B CD1 1 
ATOM   5814  C CD2 . LEU B 1 288 ? -25.747 63.163  5.570   1.00 39.35  ? 288 LEU B CD2 1 
ATOM   5815  N N   . TYR B 1 289 ? -23.349 67.471  7.593   1.00 32.67  ? 289 TYR B N   1 
ATOM   5816  C CA  . TYR B 1 289 ? -23.510 68.860  7.963   1.00 35.55  ? 289 TYR B CA  1 
ATOM   5817  C C   . TYR B 1 289 ? -22.954 69.765  6.867   1.00 42.11  ? 289 TYR B C   1 
ATOM   5818  O O   . TYR B 1 289 ? -23.500 70.836  6.596   1.00 40.26  ? 289 TYR B O   1 
ATOM   5819  C CB  . TYR B 1 289 ? -22.827 69.071  9.312   1.00 36.12  ? 289 TYR B CB  1 
ATOM   5820  C CG  . TYR B 1 289 ? -23.018 70.467  9.877   1.00 39.06  ? 289 TYR B CG  1 
ATOM   5821  C CD1 . TYR B 1 289 ? -24.125 70.783  10.651  1.00 39.61  ? 289 TYR B CD1 1 
ATOM   5822  C CD2 . TYR B 1 289 ? -22.118 71.478  9.584   1.00 42.64  ? 289 TYR B CD2 1 
ATOM   5823  C CE1 . TYR B 1 289 ? -24.316 72.063  11.139  1.00 43.00  ? 289 TYR B CE1 1 
ATOM   5824  C CE2 . TYR B 1 289 ? -22.290 72.761  10.073  1.00 46.41  ? 289 TYR B CE2 1 
ATOM   5825  C CZ  . TYR B 1 289 ? -23.391 73.051  10.855  1.00 47.45  ? 289 TYR B CZ  1 
ATOM   5826  O OH  . TYR B 1 289 ? -23.553 74.314  11.332  1.00 49.86  ? 289 TYR B OH  1 
ATOM   5827  N N   . LYS B 1 290 ? -21.871 69.328  6.225   1.00 47.70  ? 290 LYS B N   1 
ATOM   5828  C CA  . LYS B 1 290 ? -21.271 70.122  5.161   1.00 52.58  ? 290 LYS B CA  1 
ATOM   5829  C C   . LYS B 1 290 ? -22.125 70.045  3.891   1.00 48.69  ? 290 LYS B C   1 
ATOM   5830  O O   . LYS B 1 290 ? -22.262 71.031  3.175   1.00 43.42  ? 290 LYS B O   1 
ATOM   5831  C CB  . LYS B 1 290 ? -19.859 69.612  4.859   1.00 55.95  ? 290 LYS B CB  1 
ATOM   5832  C CG  . LYS B 1 290 ? -19.110 70.389  3.801   1.00 60.23  ? 290 LYS B CG  1 
ATOM   5833  C CD  . LYS B 1 290 ? -17.737 69.806  3.489   1.00 66.23  ? 290 LYS B CD  1 
ATOM   5834  C CE  . LYS B 1 290 ? -16.869 70.842  2.835   1.00 73.72  ? 290 LYS B CE  1 
ATOM   5835  N NZ  . LYS B 1 290 ? -15.577 70.309  2.393   1.00 74.86  ? 290 LYS B NZ  1 
ATOM   5836  N N   . LYS B 1 291 ? -22.663 68.854  3.606   1.00 43.32  ? 291 LYS B N   1 
ATOM   5837  C CA  . LYS B 1 291 ? -23.366 68.595  2.361   1.00 42.89  ? 291 LYS B CA  1 
ATOM   5838  C C   . LYS B 1 291 ? -24.660 69.408  2.313   1.00 44.24  ? 291 LYS B C   1 
ATOM   5839  O O   . LYS B 1 291 ? -25.019 69.950  1.267   1.00 42.08  ? 291 LYS B O   1 
ATOM   5840  C CB  . LYS B 1 291 ? -23.674 67.102  2.205   1.00 43.66  ? 291 LYS B CB  1 
ATOM   5841  C CG  . LYS B 1 291 ? -24.550 66.764  1.014   1.00 47.37  ? 291 LYS B CG  1 
ATOM   5842  C CD  . LYS B 1 291 ? -24.908 65.294  0.825   1.00 53.79  ? 291 LYS B CD  1 
ATOM   5843  C CE  . LYS B 1 291 ? -25.839 65.059  -0.350  1.00 57.90  ? 291 LYS B CE  1 
ATOM   5844  N NZ  . LYS B 1 291 ? -25.357 65.626  -1.614  1.00 55.49  ? 291 LYS B NZ  1 
ATOM   5845  N N   . PHE B 1 292 ? -25.343 69.509  3.457   1.00 42.87  ? 292 PHE B N   1 
ATOM   5846  C CA  . PHE B 1 292 ? -26.631 70.178  3.529   1.00 43.01  ? 292 PHE B CA  1 
ATOM   5847  C C   . PHE B 1 292 ? -26.522 71.592  4.117   1.00 42.25  ? 292 PHE B C   1 
ATOM   5848  O O   . PHE B 1 292 ? -27.542 72.181  4.423   1.00 49.77  ? 292 PHE B O   1 
ATOM   5849  C CB  . PHE B 1 292 ? -27.559 69.242  4.314   1.00 39.14  ? 292 PHE B CB  1 
ATOM   5850  C CG  . PHE B 1 292 ? -27.956 67.983  3.555   1.00 37.71  ? 292 PHE B CG  1 
ATOM   5851  C CD1 . PHE B 1 292 ? -28.812 68.040  2.463   1.00 40.67  ? 292 PHE B CD1 1 
ATOM   5852  C CD2 . PHE B 1 292 ? -27.503 66.733  3.948   1.00 41.59  ? 292 PHE B CD2 1 
ATOM   5853  C CE1 . PHE B 1 292 ? -29.178 66.892  1.765   1.00 38.69  ? 292 PHE B CE1 1 
ATOM   5854  C CE2 . PHE B 1 292 ? -27.868 65.584  3.244   1.00 43.54  ? 292 PHE B CE2 1 
ATOM   5855  C CZ  . PHE B 1 292 ? -28.707 65.669  2.153   1.00 41.86  ? 292 PHE B CZ  1 
ATOM   5856  N N   . GLY B 1 293 ? -25.320 72.166  4.268   1.00 41.40  ? 293 GLY B N   1 
ATOM   5857  C CA  . GLY B 1 293 ? -25.170 73.498  4.849   1.00 40.04  ? 293 GLY B CA  1 
ATOM   5858  C C   . GLY B 1 293 ? -25.764 73.616  6.258   1.00 41.89  ? 293 GLY B C   1 
ATOM   5859  O O   . GLY B 1 293 ? -26.116 74.699  6.698   1.00 42.39  ? 293 GLY B O   1 
ATOM   5860  N N   . GLY B 1 294 ? -25.862 72.499  6.985   1.00 42.52  ? 294 GLY B N   1 
ATOM   5861  C CA  . GLY B 1 294 ? -26.476 72.493  8.303   1.00 40.68  ? 294 GLY B CA  1 
ATOM   5862  C C   . GLY B 1 294 ? -27.191 71.171  8.580   1.00 42.44  ? 294 GLY B C   1 
ATOM   5863  O O   . GLY B 1 294 ? -26.948 70.156  7.920   1.00 43.00  ? 294 GLY B O   1 
ATOM   5864  N N   . VAL B 1 295 ? -28.090 71.203  9.563   1.00 43.45  ? 295 VAL B N   1 
ATOM   5865  C CA  . VAL B 1 295 ? -28.867 70.028  9.919   1.00 45.25  ? 295 VAL B CA  1 
ATOM   5866  C C   . VAL B 1 295 ? -29.778 69.713  8.745   1.00 44.64  ? 295 VAL B C   1 
ATOM   5867  O O   . VAL B 1 295 ? -30.523 70.576  8.333   1.00 45.68  ? 295 VAL B O   1 
ATOM   5868  C CB  . VAL B 1 295 ? -29.709 70.294  11.177  1.00 45.79  ? 295 VAL B CB  1 
ATOM   5869  C CG1 . VAL B 1 295 ? -30.525 69.069  11.580  1.00 44.41  ? 295 VAL B CG1 1 
ATOM   5870  C CG2 . VAL B 1 295 ? -28.853 70.815  12.330  1.00 47.20  ? 295 VAL B CG2 1 
ATOM   5871  N N   . PRO B 1 296 ? -29.760 68.516  8.129   1.00 44.87  ? 296 PRO B N   1 
ATOM   5872  C CA  . PRO B 1 296 ? -30.732 68.226  7.079   1.00 43.61  ? 296 PRO B CA  1 
ATOM   5873  C C   . PRO B 1 296 ? -32.116 68.208  7.711   1.00 45.34  ? 296 PRO B C   1 
ATOM   5874  O O   . PRO B 1 296 ? -32.236 67.961  8.913   1.00 44.12  ? 296 PRO B O   1 
ATOM   5875  C CB  . PRO B 1 296 ? -30.326 66.858  6.514   1.00 41.30  ? 296 PRO B CB  1 
ATOM   5876  C CG  . PRO B 1 296 ? -29.452 66.268  7.596   1.00 43.47  ? 296 PRO B CG  1 
ATOM   5877  C CD  . PRO B 1 296 ? -28.806 67.427  8.350   1.00 42.98  ? 296 PRO B CD  1 
ATOM   5878  N N   . THR B 1 297 ? -33.143 68.439  6.882   1.00 44.66  ? 297 THR B N   1 
ATOM   5879  C CA  . THR B 1 297 ? -34.515 68.146  7.275   1.00 46.34  ? 297 THR B CA  1 
ATOM   5880  C C   . THR B 1 297 ? -34.774 66.643  7.177   1.00 47.39  ? 297 THR B C   1 
ATOM   5881  O O   . THR B 1 297 ? -34.034 65.870  6.542   1.00 45.49  ? 297 THR B O   1 
ATOM   5882  C CB  . THR B 1 297 ? -35.530 68.904  6.418   1.00 50.99  ? 297 THR B CB  1 
ATOM   5883  O OG1 . THR B 1 297 ? -35.493 68.283  5.134   1.00 51.26  ? 297 THR B OG1 1 
ATOM   5884  C CG2 . THR B 1 297 ? -35.256 70.398  6.342   1.00 50.45  ? 297 THR B CG2 1 
ATOM   5885  N N   . LYS B 1 298 ? -35.877 66.261  7.816   1.00 48.38  ? 298 LYS B N   1 
ATOM   5886  C CA  . LYS B 1 298 ? -36.320 64.886  7.881   1.00 48.32  ? 298 LYS B CA  1 
ATOM   5887  C C   . LYS B 1 298 ? -36.370 64.349  6.463   1.00 51.57  ? 298 LYS B C   1 
ATOM   5888  O O   . LYS B 1 298 ? -35.890 63.251  6.209   1.00 54.22  ? 298 LYS B O   1 
ATOM   5889  C CB  . LYS B 1 298 ? -37.703 64.933  8.521   1.00 54.26  ? 298 LYS B CB  1 
ATOM   5890  C CG  . LYS B 1 298 ? -38.116 63.785  9.396   1.00 67.65  ? 298 LYS B CG  1 
ATOM   5891  C CD  . LYS B 1 298 ? -39.181 64.266  10.384  1.00 79.77  ? 298 LYS B CD  1 
ATOM   5892  C CE  . LYS B 1 298 ? -39.923 63.149  11.042  1.00 96.83  ? 298 LYS B CE  1 
ATOM   5893  N NZ  . LYS B 1 298 ? -40.735 62.362  10.106  1.00 110.30 ? 298 LYS B NZ  1 
ATOM   5894  N N   . GLU B 1 299 ? -36.903 65.167  5.544   1.00 59.53  ? 299 GLU B N   1 
ATOM   5895  C CA  . GLU B 1 299 ? -37.095 64.757  4.158   1.00 62.89  ? 299 GLU B CA  1 
ATOM   5896  C C   . GLU B 1 299 ? -35.741 64.527  3.462   1.00 52.36  ? 299 GLU B C   1 
ATOM   5897  O O   . GLU B 1 299 ? -35.577 63.526  2.766   1.00 46.86  ? 299 GLU B O   1 
ATOM   5898  C CB  . GLU B 1 299 ? -38.043 65.727  3.447   1.00 64.54  ? 299 GLU B CB  1 
ATOM   5899  C CG  . GLU B 1 299 ? -38.813 65.079  2.298   1.00 77.08  ? 299 GLU B CG  1 
ATOM   5900  C CD  . GLU B 1 299 ? -39.922 65.914  1.657   1.00 89.29  ? 299 GLU B CD  1 
ATOM   5901  O OE1 . GLU B 1 299 ? -40.806 66.451  2.368   1.00 97.08  ? 299 GLU B OE1 1 
ATOM   5902  O OE2 . GLU B 1 299 ? -39.926 66.000  0.409   1.00 86.85  ? 299 GLU B OE2 1 
ATOM   5903  N N   . GLN B 1 300 ? -34.755 65.411  3.677   1.00 47.29  ? 300 GLN B N   1 
ATOM   5904  C CA  . GLN B 1 300 ? -33.479 65.331  2.973   1.00 44.50  ? 300 GLN B CA  1 
ATOM   5905  C C   . GLN B 1 300 ? -32.637 64.130  3.419   1.00 45.45  ? 300 GLN B C   1 
ATOM   5906  O O   . GLN B 1 300 ? -31.958 63.523  2.595   1.00 43.43  ? 300 GLN B O   1 
ATOM   5907  C CB  . GLN B 1 300 ? -32.641 66.581  3.216   1.00 42.73  ? 300 GLN B CB  1 
ATOM   5908  C CG  . GLN B 1 300 ? -33.182 67.847  2.568   1.00 39.87  ? 300 GLN B CG  1 
ATOM   5909  C CD  . GLN B 1 300 ? -32.411 69.084  2.984   1.00 41.21  ? 300 GLN B CD  1 
ATOM   5910  O OE1 . GLN B 1 300 ? -32.394 69.474  4.162   1.00 41.16  ? 300 GLN B OE1 1 
ATOM   5911  N NE2 . GLN B 1 300 ? -31.758 69.715  2.015   1.00 43.67  ? 300 GLN B NE2 1 
ATOM   5912  N N   . LEU B 1 301 ? -32.653 63.825  4.728   1.00 47.94  ? 301 LEU B N   1 
ATOM   5913  C CA  . LEU B 1 301 ? -31.893 62.721  5.308   1.00 42.74  ? 301 LEU B CA  1 
ATOM   5914  C C   . LEU B 1 301 ? -32.474 61.383  4.853   1.00 43.85  ? 301 LEU B C   1 
ATOM   5915  O O   . LEU B 1 301 ? -31.717 60.434  4.618   1.00 41.77  ? 301 LEU B O   1 
ATOM   5916  C CB  . LEU B 1 301 ? -31.898 62.810  6.835   1.00 39.58  ? 301 LEU B CB  1 
ATOM   5917  C CG  . LEU B 1 301 ? -31.047 61.766  7.574   1.00 40.21  ? 301 LEU B CG  1 
ATOM   5918  C CD1 . LEU B 1 301 ? -29.555 62.055  7.443   1.00 35.51  ? 301 LEU B CD1 1 
ATOM   5919  C CD2 . LEU B 1 301 ? -31.442 61.666  9.034   1.00 35.76  ? 301 LEU B CD2 1 
ATOM   5920  N N   . GLU B 1 302 ? -33.820 61.327  4.811   1.00 47.50  ? 302 GLU B N   1 
ATOM   5921  C CA  . GLU B 1 302 ? -34.584 60.186  4.319   1.00 49.37  ? 302 GLU B CA  1 
ATOM   5922  C C   . GLU B 1 302 ? -34.107 59.805  2.924   1.00 48.19  ? 302 GLU B C   1 
ATOM   5923  O O   . GLU B 1 302 ? -33.819 58.638  2.671   1.00 38.69  ? 302 GLU B O   1 
ATOM   5924  C CB  . GLU B 1 302 ? -36.082 60.482  4.223   1.00 51.36  ? 302 GLU B CB  1 
ATOM   5925  C CG  . GLU B 1 302 ? -36.921 59.825  5.313   1.00 58.02  ? 302 GLU B CG  1 
ATOM   5926  C CD  . GLU B 1 302 ? -38.341 60.360  5.456   1.00 58.62  ? 302 GLU B CD  1 
ATOM   5927  O OE1 . GLU B 1 302 ? -39.145 60.204  4.526   1.00 57.90  ? 302 GLU B OE1 1 
ATOM   5928  O OE2 . GLU B 1 302 ? -38.652 60.918  6.529   1.00 64.80  ? 302 GLU B OE2 1 
ATOM   5929  N N   . ARG B 1 303 ? -34.049 60.827  2.053   1.00 51.84  ? 303 ARG B N   1 
ATOM   5930  C CA  . ARG B 1 303 ? -33.666 60.685  0.661   1.00 49.20  ? 303 ARG B CA  1 
ATOM   5931  C C   . ARG B 1 303 ? -32.212 60.240  0.611   1.00 44.14  ? 303 ARG B C   1 
ATOM   5932  O O   . ARG B 1 303 ? -31.899 59.252  -0.037  1.00 42.59  ? 303 ARG B O   1 
ATOM   5933  C CB  . ARG B 1 303 ? -33.938 62.013  -0.056  1.00 56.71  ? 303 ARG B CB  1 
ATOM   5934  C CG  . ARG B 1 303 ? -33.980 61.946  -1.578  1.00 75.71  ? 303 ARG B CG  1 
ATOM   5935  C CD  . ARG B 1 303 ? -35.109 62.804  -2.179  1.00 87.95  ? 303 ARG B CD  1 
ATOM   5936  N NE  . ARG B 1 303 ? -35.226 64.148  -1.587  1.00 96.93  ? 303 ARG B NE  1 
ATOM   5937  C CZ  . ARG B 1 303 ? -36.289 64.657  -0.936  1.00 93.64  ? 303 ARG B CZ  1 
ATOM   5938  N NH1 . ARG B 1 303 ? -37.411 63.960  -0.826  1.00 92.71  ? 303 ARG B NH1 1 
ATOM   5939  N NH2 . ARG B 1 303 ? -36.226 65.864  -0.389  1.00 78.67  ? 303 ARG B NH2 1 
ATOM   5940  N N   . PHE B 1 304 ? -31.346 60.956  1.339   1.00 41.53  ? 304 PHE B N   1 
ATOM   5941  C CA  . PHE B 1 304 ? -29.932 60.624  1.398   1.00 41.11  ? 304 PHE B CA  1 
ATOM   5942  C C   . PHE B 1 304 ? -29.726 59.198  1.905   1.00 38.47  ? 304 PHE B C   1 
ATOM   5943  O O   . PHE B 1 304 ? -28.848 58.493  1.432   1.00 37.96  ? 304 PHE B O   1 
ATOM   5944  C CB  . PHE B 1 304 ? -29.155 61.578  2.304   1.00 41.15  ? 304 PHE B CB  1 
ATOM   5945  C CG  . PHE B 1 304 ? -27.668 61.265  2.311   1.00 39.20  ? 304 PHE B CG  1 
ATOM   5946  C CD1 . PHE B 1 304 ? -26.822 61.841  1.379   1.00 40.62  ? 304 PHE B CD1 1 
ATOM   5947  C CD2 . PHE B 1 304 ? -27.125 60.394  3.245   1.00 41.98  ? 304 PHE B CD2 1 
ATOM   5948  C CE1 . PHE B 1 304 ? -25.470 61.550  1.368   1.00 41.32  ? 304 PHE B CE1 1 
ATOM   5949  C CE2 . PHE B 1 304 ? -25.769 60.097  3.227   1.00 46.15  ? 304 PHE B CE2 1 
ATOM   5950  C CZ  . PHE B 1 304 ? -24.948 60.672  2.283   1.00 46.04  ? 304 PHE B CZ  1 
ATOM   5951  N N   . ALA B 1 305 ? -30.531 58.773  2.872   1.00 37.27  ? 305 ALA B N   1 
ATOM   5952  C CA  . ALA B 1 305 ? -30.381 57.443  3.427   1.00 38.90  ? 305 ALA B CA  1 
ATOM   5953  C C   . ALA B 1 305 ? -30.779 56.364  2.411   1.00 39.81  ? 305 ALA B C   1 
ATOM   5954  O O   . ALA B 1 305 ? -30.135 55.313  2.357   1.00 40.25  ? 305 ALA B O   1 
ATOM   5955  C CB  . ALA B 1 305 ? -31.163 57.350  4.719   1.00 38.66  ? 305 ALA B CB  1 
ATOM   5956  N N   . TRP B 1 306 ? -31.836 56.619  1.613   1.00 42.48  ? 306 TRP B N   1 
ATOM   5957  C CA  . TRP B 1 306 ? -32.303 55.702  0.568   1.00 39.86  ? 306 TRP B CA  1 
ATOM   5958  C C   . TRP B 1 306 ? -31.293 55.614  -0.579  1.00 36.62  ? 306 TRP B C   1 
ATOM   5959  O O   . TRP B 1 306 ? -30.955 54.525  -1.035  1.00 35.58  ? 306 TRP B O   1 
ATOM   5960  C CB  . TRP B 1 306 ? -33.697 56.106  0.044   1.00 40.62  ? 306 TRP B CB  1 
ATOM   5961  C CG  . TRP B 1 306 ? -34.855 55.661  0.903   1.00 37.81  ? 306 TRP B CG  1 
ATOM   5962  C CD1 . TRP B 1 306 ? -35.628 56.420  1.734   1.00 37.70  ? 306 TRP B CD1 1 
ATOM   5963  C CD2 . TRP B 1 306 ? -35.355 54.314  1.030   1.00 38.21  ? 306 TRP B CD2 1 
ATOM   5964  N NE1 . TRP B 1 306 ? -36.579 55.650  2.353   1.00 35.05  ? 306 TRP B NE1 1 
ATOM   5965  C CE2 . TRP B 1 306 ? -36.431 54.354  1.943   1.00 40.00  ? 306 TRP B CE2 1 
ATOM   5966  C CE3 . TRP B 1 306 ? -35.002 53.091  0.462   1.00 40.53  ? 306 TRP B CE3 1 
ATOM   5967  C CZ2 . TRP B 1 306 ? -37.144 53.212  2.299   1.00 46.51  ? 306 TRP B CZ2 1 
ATOM   5968  C CZ3 . TRP B 1 306 ? -35.704 51.961  0.816   1.00 45.86  ? 306 TRP B CZ3 1 
ATOM   5969  C CH2 . TRP B 1 306 ? -36.758 52.022  1.726   1.00 49.02  ? 306 TRP B CH2 1 
ATOM   5970  N N   . ASP B 1 307 ? -30.757 56.754  -1.009  1.00 37.13  ? 307 ASP B N   1 
ATOM   5971  C CA  . ASP B 1 307 ? -29.734 56.746  -2.041  1.00 40.77  ? 307 ASP B CA  1 
ATOM   5972  C C   . ASP B 1 307 ? -28.532 55.934  -1.574  1.00 43.51  ? 307 ASP B C   1 
ATOM   5973  O O   . ASP B 1 307 ? -28.054 55.087  -2.322  1.00 44.89  ? 307 ASP B O   1 
ATOM   5974  C CB  . ASP B 1 307 ? -29.399 58.153  -2.496  1.00 42.12  ? 307 ASP B CB  1 
ATOM   5975  C CG  . ASP B 1 307 ? -30.581 58.858  -3.150  1.00 48.01  ? 307 ASP B CG  1 
ATOM   5976  O OD1 . ASP B 1 307 ? -31.608 58.195  -3.387  1.00 51.89  ? 307 ASP B OD1 1 
ATOM   5977  O OD2 . ASP B 1 307 ? -30.492 60.061  -3.400  1.00 50.18  ? 307 ASP B OD2 1 
ATOM   5978  N N   . THR B 1 308 ? -28.073 56.198  -0.337  1.00 46.42  ? 308 THR B N   1 
ATOM   5979  C CA  . THR B 1 308 ? -26.924 55.531  0.274   1.00 42.48  ? 308 THR B CA  1 
ATOM   5980  C C   . THR B 1 308 ? -27.108 54.016  0.222   1.00 38.16  ? 308 THR B C   1 
ATOM   5981  O O   . THR B 1 308 ? -26.247 53.274  -0.232  1.00 34.30  ? 308 THR B O   1 
ATOM   5982  C CB  . THR B 1 308 ? -26.781 56.003  1.725   1.00 44.19  ? 308 THR B CB  1 
ATOM   5983  O OG1 . THR B 1 308 ? -26.256 57.326  1.699   1.00 47.08  ? 308 THR B OG1 1 
ATOM   5984  C CG2 . THR B 1 308 ? -25.843 55.128  2.533   1.00 43.37  ? 308 THR B CG2 1 
ATOM   5985  N N   . LEU B 1 309 ? -28.236 53.556  0.753   1.00 42.50  ? 309 LEU B N   1 
ATOM   5986  C CA  . LEU B 1 309 ? -28.478 52.132  0.877   1.00 44.38  ? 309 LEU B CA  1 
ATOM   5987  C C   . LEU B 1 309 ? -28.699 51.526  -0.507  1.00 44.54  ? 309 LEU B C   1 
ATOM   5988  O O   . LEU B 1 309 ? -28.150 50.468  -0.812  1.00 46.49  ? 309 LEU B O   1 
ATOM   5989  C CB  . LEU B 1 309 ? -29.666 51.924  1.815   1.00 44.29  ? 309 LEU B CB  1 
ATOM   5990  C CG  . LEU B 1 309 ? -29.399 52.174  3.301   1.00 40.29  ? 309 LEU B CG  1 
ATOM   5991  C CD1 . LEU B 1 309 ? -30.709 52.199  4.057   1.00 42.80  ? 309 LEU B CD1 1 
ATOM   5992  C CD2 . LEU B 1 309 ? -28.509 51.099  3.868   1.00 41.27  ? 309 LEU B CD2 1 
ATOM   5993  N N   . ASN B 1 310 ? -29.460 52.221  -1.361  1.00 41.72  ? 310 ASN B N   1 
ATOM   5994  C CA  . ASN B 1 310 ? -29.668 51.730  -2.713  1.00 45.51  ? 310 ASN B CA  1 
ATOM   5995  C C   . ASN B 1 310 ? -28.371 51.679  -3.517  1.00 44.84  ? 310 ASN B C   1 
ATOM   5996  O O   . ASN B 1 310 ? -28.295 50.903  -4.458  1.00 51.06  ? 310 ASN B O   1 
ATOM   5997  C CB  . ASN B 1 310 ? -30.746 52.500  -3.461  1.00 41.47  ? 310 ASN B CB  1 
ATOM   5998  C CG  . ASN B 1 310 ? -32.106 52.063  -2.995  1.00 41.02  ? 310 ASN B CG  1 
ATOM   5999  O OD1 . ASN B 1 310 ? -32.217 51.145  -2.174  1.00 41.96  ? 310 ASN B OD1 1 
ATOM   6000  N ND2 . ASN B 1 310 ? -33.141 52.709  -3.502  1.00 43.97  ? 310 ASN B ND2 1 
ATOM   6001  N N   . SER B 1 311 ? -27.362 52.485  -3.173  1.00 43.93  ? 311 SER B N   1 
ATOM   6002  C CA  . SER B 1 311 ? -26.080 52.365  -3.838  1.00 45.00  ? 311 SER B CA  1 
ATOM   6003  C C   . SER B 1 311 ? -25.205 51.313  -3.141  1.00 47.59  ? 311 SER B C   1 
ATOM   6004  O O   . SER B 1 311 ? -24.036 51.186  -3.454  1.00 49.55  ? 311 SER B O   1 
ATOM   6005  C CB  . SER B 1 311 ? -25.415 53.710  -3.959  1.00 47.97  ? 311 SER B CB  1 
ATOM   6006  O OG  . SER B 1 311 ? -24.658 54.007  -2.798  1.00 56.16  ? 311 SER B OG  1 
ATOM   6007  N N   . GLY B 1 312 ? -25.775 50.528  -2.215  1.00 55.01  ? 312 GLY B N   1 
ATOM   6008  C CA  . GLY B 1 312 ? -25.112 49.367  -1.637  1.00 55.62  ? 312 GLY B CA  1 
ATOM   6009  C C   . GLY B 1 312 ? -24.107 49.725  -0.536  1.00 61.17  ? 312 GLY B C   1 
ATOM   6010  O O   . GLY B 1 312 ? -23.248 48.911  -0.208  1.00 57.34  ? 312 GLY B O   1 
ATOM   6011  N N   . GLN B 1 313 ? -24.222 50.937  0.028   1.00 63.74  ? 313 GLN B N   1 
ATOM   6012  C CA  . GLN B 1 313 ? -23.432 51.367  1.173   1.00 62.65  ? 313 GLN B CA  1 
ATOM   6013  C C   . GLN B 1 313 ? -24.166 51.047  2.474   1.00 63.48  ? 313 GLN B C   1 
ATOM   6014  O O   . GLN B 1 313 ? -25.381 50.873  2.457   1.00 66.35  ? 313 GLN B O   1 
ATOM   6015  C CB  . GLN B 1 313 ? -23.281 52.881  1.104   1.00 62.88  ? 313 GLN B CB  1 
ATOM   6016  C CG  . GLN B 1 313 ? -22.472 53.369  -0.086  1.00 63.60  ? 313 GLN B CG  1 
ATOM   6017  C CD  . GLN B 1 313 ? -21.073 53.753  0.325   1.00 73.24  ? 313 GLN B CD  1 
ATOM   6018  O OE1 . GLN B 1 313 ? -20.613 54.865  0.041   1.00 72.95  ? 313 GLN B OE1 1 
ATOM   6019  N NE2 . GLN B 1 313 ? -20.406 52.854  1.042   1.00 78.01  ? 313 GLN B NE2 1 
ATOM   6020  N N   . VAL B 1 314 ? -23.428 51.004  3.595   1.00 63.96  ? 314 VAL B N   1 
ATOM   6021  C CA  . VAL B 1 314 ? -24.028 50.880  4.924   1.00 64.60  ? 314 VAL B CA  1 
ATOM   6022  C C   . VAL B 1 314 ? -24.152 52.275  5.525   1.00 53.31  ? 314 VAL B C   1 
ATOM   6023  O O   . VAL B 1 314 ? -23.448 53.197  5.119   1.00 52.43  ? 314 VAL B O   1 
ATOM   6024  C CB  . VAL B 1 314 ? -23.305 49.974  5.949   1.00 66.18  ? 314 VAL B CB  1 
ATOM   6025  C CG1 . VAL B 1 314 ? -23.776 48.520  5.874   1.00 66.93  ? 314 VAL B CG1 1 
ATOM   6026  C CG2 . VAL B 1 314 ? -21.784 50.097  5.878   1.00 60.03  ? 314 VAL B CG2 1 
ATOM   6027  N N   . ILE B 1 315 ? -25.025 52.395  6.527   1.00 47.29  ? 315 ILE B N   1 
ATOM   6028  C CA  . ILE B 1 315 ? -25.083 53.603  7.331   1.00 43.23  ? 315 ILE B CA  1 
ATOM   6029  C C   . ILE B 1 315 ? -24.262 53.390  8.599   1.00 41.72  ? 315 ILE B C   1 
ATOM   6030  O O   . ILE B 1 315 ? -24.545 52.490  9.377   1.00 46.80  ? 315 ILE B O   1 
ATOM   6031  C CB  . ILE B 1 315 ? -26.539 53.989  7.614   1.00 41.64  ? 315 ILE B CB  1 
ATOM   6032  C CG1 . ILE B 1 315 ? -27.175 54.545  6.328   1.00 42.49  ? 315 ILE B CG1 1 
ATOM   6033  C CG2 . ILE B 1 315 ? -26.620 54.978  8.784   1.00 41.32  ? 315 ILE B CG2 1 
ATOM   6034  C CD1 . ILE B 1 315 ? -28.681 54.599  6.349   1.00 43.53  ? 315 ILE B CD1 1 
ATOM   6035  N N   . PRO B 1 316 ? -23.202 54.188  8.844   1.00 40.05  ? 316 PRO B N   1 
ATOM   6036  C CA  . PRO B 1 316 ? -22.329 53.951  9.989   1.00 37.89  ? 316 PRO B CA  1 
ATOM   6037  C C   . PRO B 1 316 ? -23.067 54.136  11.308  1.00 35.78  ? 316 PRO B C   1 
ATOM   6038  O O   . PRO B 1 316 ? -23.822 55.088  11.480  1.00 39.84  ? 316 PRO B O   1 
ATOM   6039  C CB  . PRO B 1 316 ? -21.180 54.958  9.825   1.00 39.79  ? 316 PRO B CB  1 
ATOM   6040  C CG  . PRO B 1 316 ? -21.283 55.474  8.403   1.00 41.00  ? 316 PRO B CG  1 
ATOM   6041  C CD  . PRO B 1 316 ? -22.756 55.322  8.019   1.00 41.96  ? 316 PRO B CD  1 
ATOM   6042  N N   . GLY B 1 317 ? -22.844 53.195  12.229  1.00 37.70  ? 317 GLY B N   1 
ATOM   6043  C CA  . GLY B 1 317 ? -23.417 53.268  13.561  1.00 37.48  ? 317 GLY B CA  1 
ATOM   6044  C C   . GLY B 1 317 ? -24.728 52.495  13.693  1.00 38.67  ? 317 GLY B C   1 
ATOM   6045  O O   . GLY B 1 317 ? -25.208 52.341  14.813  1.00 40.94  ? 317 GLY B O   1 
ATOM   6046  N N   . TYR B 1 318 ? -25.301 52.022  12.568  1.00 42.45  ? 318 TYR B N   1 
ATOM   6047  C CA  . TYR B 1 318 ? -26.611 51.373  12.544  1.00 41.07  ? 318 TYR B CA  1 
ATOM   6048  C C   . TYR B 1 318 ? -26.527 49.998  11.875  1.00 45.45  ? 318 TYR B C   1 
ATOM   6049  O O   . TYR B 1 318 ? -25.786 49.780  10.919  1.00 49.98  ? 318 TYR B O   1 
ATOM   6050  C CB  . TYR B 1 318 ? -27.611 52.259  11.795  1.00 36.98  ? 318 TYR B CB  1 
ATOM   6051  C CG  . TYR B 1 318 ? -28.103 53.500  12.534  1.00 31.86  ? 318 TYR B CG  1 
ATOM   6052  C CD1 . TYR B 1 318 ? -27.319 54.629  12.660  1.00 30.65  ? 318 TYR B CD1 1 
ATOM   6053  C CD2 . TYR B 1 318 ? -29.391 53.560  13.052  1.00 32.04  ? 318 TYR B CD2 1 
ATOM   6054  C CE1 . TYR B 1 318 ? -27.771 55.749  13.350  1.00 34.25  ? 318 TYR B CE1 1 
ATOM   6055  C CE2 . TYR B 1 318 ? -29.869 54.679  13.717  1.00 30.76  ? 318 TYR B CE2 1 
ATOM   6056  C CZ  . TYR B 1 318 ? -29.047 55.774  13.888  1.00 32.56  ? 318 TYR B CZ  1 
ATOM   6057  O OH  . TYR B 1 318 ? -29.513 56.855  14.571  1.00 33.78  ? 318 TYR B OH  1 
ATOM   6058  N N   . GLY B 1 319 ? -27.295 49.055  12.407  1.00 46.50  ? 319 GLY B N   1 
ATOM   6059  C CA  . GLY B 1 319 ? -27.635 47.858  11.669  1.00 48.77  ? 319 GLY B CA  1 
ATOM   6060  C C   . GLY B 1 319 ? -26.640 46.720  11.866  1.00 55.41  ? 319 GLY B C   1 
ATOM   6061  O O   . GLY B 1 319 ? -26.605 45.828  11.032  1.00 58.30  ? 319 GLY B O   1 
ATOM   6062  N N   . HIS B 1 320 ? -25.889 46.706  12.976  1.00 56.79  ? 320 HIS B N   1 
ATOM   6063  C CA  . HIS B 1 320 ? -25.027 45.573  13.286  1.00 63.25  ? 320 HIS B CA  1 
ATOM   6064  C C   . HIS B 1 320 ? -25.915 44.405  13.715  1.00 69.70  ? 320 HIS B C   1 
ATOM   6065  O O   . HIS B 1 320 ? -27.071 44.623  14.058  1.00 73.97  ? 320 HIS B O   1 
ATOM   6066  C CB  . HIS B 1 320 ? -23.922 46.014  14.251  1.00 71.53  ? 320 HIS B CB  1 
ATOM   6067  C CG  . HIS B 1 320 ? -22.934 46.922  13.587  1.00 74.83  ? 320 HIS B CG  1 
ATOM   6068  N ND1 . HIS B 1 320 ? -21.708 46.489  13.121  1.00 73.71  ? 320 HIS B ND1 1 
ATOM   6069  C CD2 . HIS B 1 320 ? -23.008 48.234  13.286  1.00 74.33  ? 320 HIS B CD2 1 
ATOM   6070  C CE1 . HIS B 1 320 ? -21.066 47.514  12.563  1.00 76.86  ? 320 HIS B CE1 1 
ATOM   6071  N NE2 . HIS B 1 320 ? -21.838 48.585  12.655  1.00 74.51  ? 320 HIS B NE2 1 
ATOM   6072  N N   . ALA B 1 321 ? -25.387 43.170  13.690  1.00 73.71  ? 321 ALA B N   1 
ATOM   6073  C CA  . ALA B 1 321 ? -26.222 41.989  13.472  1.00 71.34  ? 321 ALA B CA  1 
ATOM   6074  C C   . ALA B 1 321 ? -26.703 41.291  14.752  1.00 67.84  ? 321 ALA B C   1 
ATOM   6075  O O   . ALA B 1 321 ? -27.649 40.501  14.683  1.00 65.97  ? 321 ALA B O   1 
ATOM   6076  C CB  . ALA B 1 321 ? -25.487 41.005  12.578  1.00 73.28  ? 321 ALA B CB  1 
ATOM   6077  N N   . VAL B 1 322 ? -26.052 41.500  15.905  1.00 65.73  ? 322 VAL B N   1 
ATOM   6078  C CA  . VAL B 1 322 ? -26.375 40.666  17.056  1.00 68.44  ? 322 VAL B CA  1 
ATOM   6079  C C   . VAL B 1 322 ? -27.683 41.187  17.671  1.00 64.36  ? 322 VAL B C   1 
ATOM   6080  O O   . VAL B 1 322 ? -28.667 40.446  17.709  1.00 60.99  ? 322 VAL B O   1 
ATOM   6081  C CB  . VAL B 1 322 ? -25.230 40.480  18.084  1.00 67.29  ? 322 VAL B CB  1 
ATOM   6082  C CG1 . VAL B 1 322 ? -25.664 39.672  19.307  1.00 69.16  ? 322 VAL B CG1 1 
ATOM   6083  C CG2 . VAL B 1 322 ? -24.000 39.816  17.470  1.00 63.54  ? 322 VAL B CG2 1 
ATOM   6084  N N   . LEU B 1 323 ? -27.699 42.466  18.090  1.00 57.36  ? 323 LEU B N   1 
ATOM   6085  C CA  . LEU B 1 323 ? -28.851 43.093  18.730  1.00 55.65  ? 323 LEU B CA  1 
ATOM   6086  C C   . LEU B 1 323 ? -30.055 43.085  17.802  1.00 53.51  ? 323 LEU B C   1 
ATOM   6087  O O   . LEU B 1 323 ? -29.909 43.078  16.591  1.00 51.19  ? 323 LEU B O   1 
ATOM   6088  C CB  . LEU B 1 323 ? -28.607 44.544  19.131  1.00 51.51  ? 323 LEU B CB  1 
ATOM   6089  C CG  . LEU B 1 323 ? -27.623 44.757  20.273  1.00 51.93  ? 323 LEU B CG  1 
ATOM   6090  C CD1 . LEU B 1 323 ? -27.447 46.236  20.586  1.00 52.53  ? 323 LEU B CD1 1 
ATOM   6091  C CD2 . LEU B 1 323 ? -28.148 43.969  21.445  1.00 53.66  ? 323 LEU B CD2 1 
ATOM   6092  N N   . ARG B 1 324 ? -31.236 43.135  18.416  1.00 49.74  ? 324 ARG B N   1 
ATOM   6093  C CA  . ARG B 1 324 ? -32.469 43.429  17.714  1.00 50.42  ? 324 ARG B CA  1 
ATOM   6094  C C   . ARG B 1 324 ? -33.126 44.674  18.309  1.00 45.10  ? 324 ARG B C   1 
ATOM   6095  O O   . ARG B 1 324 ? -34.266 44.984  17.958  1.00 39.78  ? 324 ARG B O   1 
ATOM   6096  C CB  . ARG B 1 324 ? -33.384 42.198  17.755  1.00 54.97  ? 324 ARG B CB  1 
ATOM   6097  C CG  . ARG B 1 324 ? -33.198 41.247  16.580  1.00 64.20  ? 324 ARG B CG  1 
ATOM   6098  C CD  . ARG B 1 324 ? -34.292 40.199  16.573  1.00 73.77  ? 324 ARG B CD  1 
ATOM   6099  N NE  . ARG B 1 324 ? -34.210 39.480  17.850  1.00 83.94  ? 324 ARG B NE  1 
ATOM   6100  C CZ  . ARG B 1 324 ? -33.648 38.287  18.031  1.00 82.43  ? 324 ARG B CZ  1 
ATOM   6101  N NH1 . ARG B 1 324 ? -33.268 37.578  16.981  1.00 88.04  ? 324 ARG B NH1 1 
ATOM   6102  N NH2 . ARG B 1 324 ? -33.506 37.790  19.250  1.00 67.65  ? 324 ARG B NH2 1 
ATOM   6103  N N   . VAL B 1 325 ? -32.402 45.383  19.198  1.00 44.81  ? 325 VAL B N   1 
ATOM   6104  C CA  . VAL B 1 325 ? -32.904 46.609  19.816  1.00 42.99  ? 325 VAL B CA  1 
ATOM   6105  C C   . VAL B 1 325 ? -31.798 47.662  19.776  1.00 35.44  ? 325 VAL B C   1 
ATOM   6106  O O   . VAL B 1 325 ? -30.624 47.337  19.584  1.00 33.07  ? 325 VAL B O   1 
ATOM   6107  C CB  . VAL B 1 325 ? -33.424 46.434  21.265  1.00 44.72  ? 325 VAL B CB  1 
ATOM   6108  C CG1 . VAL B 1 325 ? -34.763 45.699  21.319  1.00 44.07  ? 325 VAL B CG1 1 
ATOM   6109  C CG2 . VAL B 1 325 ? -32.409 45.746  22.177  1.00 43.61  ? 325 VAL B CG2 1 
ATOM   6110  N N   . THR B 1 326 ? -32.200 48.921  19.968  1.00 31.24  ? 326 THR B N   1 
ATOM   6111  C CA  . THR B 1 326 ? -31.250 49.971  20.278  1.00 35.44  ? 326 THR B CA  1 
ATOM   6112  C C   . THR B 1 326 ? -30.346 49.492  21.412  1.00 38.90  ? 326 THR B C   1 
ATOM   6113  O O   . THR B 1 326 ? -30.820 48.859  22.362  1.00 36.84  ? 326 THR B O   1 
ATOM   6114  C CB  . THR B 1 326 ? -31.957 51.270  20.660  1.00 35.26  ? 326 THR B CB  1 
ATOM   6115  O OG1 . THR B 1 326 ? -32.549 51.766  19.470  1.00 35.19  ? 326 THR B OG1 1 
ATOM   6116  C CG2 . THR B 1 326 ? -30.997 52.340  21.136  1.00 35.43  ? 326 THR B CG2 1 
ATOM   6117  N N   . ASP B 1 327 ? -29.046 49.805  21.259  1.00 38.20  ? 327 ASP B N   1 
ATOM   6118  C CA  . ASP B 1 327 ? -27.996 49.584  22.246  1.00 35.66  ? 327 ASP B CA  1 
ATOM   6119  C C   . ASP B 1 327 ? -28.246 50.487  23.448  1.00 30.17  ? 327 ASP B C   1 
ATOM   6120  O O   . ASP B 1 327 ? -28.340 51.709  23.322  1.00 29.23  ? 327 ASP B O   1 
ATOM   6121  C CB  . ASP B 1 327 ? -26.624 49.863  21.636  1.00 38.30  ? 327 ASP B CB  1 
ATOM   6122  C CG  . ASP B 1 327 ? -25.350 49.495  22.405  1.00 36.17  ? 327 ASP B CG  1 
ATOM   6123  O OD1 . ASP B 1 327 ? -25.408 49.110  23.584  1.00 28.15  ? 327 ASP B OD1 1 
ATOM   6124  O OD2 . ASP B 1 327 ? -24.276 49.588  21.782  1.00 40.55  ? 327 ASP B OD2 1 
ATOM   6125  N N   . PRO B 1 328 ? -28.368 49.908  24.656  1.00 28.59  ? 328 PRO B N   1 
ATOM   6126  C CA  . PRO B 1 328 ? -28.586 50.709  25.848  1.00 28.99  ? 328 PRO B CA  1 
ATOM   6127  C C   . PRO B 1 328 ? -27.455 51.708  26.047  1.00 32.37  ? 328 PRO B C   1 
ATOM   6128  O O   . PRO B 1 328 ? -27.676 52.792  26.600  1.00 34.18  ? 328 PRO B O   1 
ATOM   6129  C CB  . PRO B 1 328 ? -28.708 49.700  26.970  1.00 28.89  ? 328 PRO B CB  1 
ATOM   6130  C CG  . PRO B 1 328 ? -28.205 48.389  26.396  1.00 28.21  ? 328 PRO B CG  1 
ATOM   6131  C CD  . PRO B 1 328 ? -28.367 48.461  24.918  1.00 28.49  ? 328 PRO B CD  1 
ATOM   6132  N N   . ARG B 1 329 ? -26.256 51.361  25.549  1.00 30.91  ? 329 ARG B N   1 
ATOM   6133  C CA  . ARG B 1 329 ? -25.137 52.291  25.614  1.00 29.23  ? 329 ARG B CA  1 
ATOM   6134  C C   . ARG B 1 329 ? -25.443 53.518  24.758  1.00 26.95  ? 329 ARG B C   1 
ATOM   6135  O O   . ARG B 1 329 ? -25.084 54.633  25.114  1.00 28.42  ? 329 ARG B O   1 
ATOM   6136  C CB  . ARG B 1 329 ? -23.831 51.590  25.225  1.00 31.58  ? 329 ARG B CB  1 
ATOM   6137  C CG  . ARG B 1 329 ? -23.384 50.488  26.174  1.00 32.78  ? 329 ARG B CG  1 
ATOM   6138  C CD  . ARG B 1 329 ? -22.193 49.686  25.672  1.00 32.09  ? 329 ARG B CD  1 
ATOM   6139  N NE  . ARG B 1 329 ? -22.455 49.014  24.398  1.00 32.98  ? 329 ARG B NE  1 
ATOM   6140  C CZ  . ARG B 1 329 ? -21.493 48.468  23.673  1.00 32.83  ? 329 ARG B CZ  1 
ATOM   6141  N NH1 . ARG B 1 329 ? -20.249 48.427  24.147  1.00 32.40  ? 329 ARG B NH1 1 
ATOM   6142  N NH2 . ARG B 1 329 ? -21.783 47.956  22.496  1.00 28.60  ? 329 ARG B NH2 1 
ATOM   6143  N N   . TYR B 1 330 ? -26.108 53.320  23.618  1.00 26.60  ? 330 TYR B N   1 
ATOM   6144  C CA  . TYR B 1 330 ? -26.524 54.455  22.820  1.00 29.51  ? 330 TYR B CA  1 
ATOM   6145  C C   . TYR B 1 330 ? -27.493 55.331  23.636  1.00 28.32  ? 330 TYR B C   1 
ATOM   6146  O O   . TYR B 1 330 ? -27.323 56.548  23.654  1.00 26.38  ? 330 TYR B O   1 
ATOM   6147  C CB  . TYR B 1 330 ? -27.025 54.011  21.437  1.00 29.29  ? 330 TYR B CB  1 
ATOM   6148  C CG  . TYR B 1 330 ? -27.497 55.159  20.548  1.00 29.10  ? 330 TYR B CG  1 
ATOM   6149  C CD1 . TYR B 1 330 ? -28.774 55.701  20.689  1.00 29.43  ? 330 TYR B CD1 1 
ATOM   6150  C CD2 . TYR B 1 330 ? -26.690 55.682  19.549  1.00 31.22  ? 330 TYR B CD2 1 
ATOM   6151  C CE1 . TYR B 1 330 ? -29.211 56.753  19.903  1.00 29.29  ? 330 TYR B CE1 1 
ATOM   6152  C CE2 . TYR B 1 330 ? -27.126 56.721  18.735  1.00 32.10  ? 330 TYR B CE2 1 
ATOM   6153  C CZ  . TYR B 1 330 ? -28.388 57.267  18.922  1.00 31.72  ? 330 TYR B CZ  1 
ATOM   6154  O OH  . TYR B 1 330 ? -28.837 58.303  18.148  1.00 35.92  ? 330 TYR B OH  1 
ATOM   6155  N N   . VAL B 1 331 ? -28.502 54.729  24.293  1.00 30.58  ? 331 VAL B N   1 
ATOM   6156  C CA  . VAL B 1 331 ? -29.571 55.467  24.991  1.00 31.69  ? 331 VAL B CA  1 
ATOM   6157  C C   . VAL B 1 331 ? -28.939 56.322  26.101  1.00 30.82  ? 331 VAL B C   1 
ATOM   6158  O O   . VAL B 1 331 ? -29.265 57.503  26.277  1.00 26.53  ? 331 VAL B O   1 
ATOM   6159  C CB  . VAL B 1 331 ? -30.681 54.539  25.568  1.00 31.13  ? 331 VAL B CB  1 
ATOM   6160  C CG1 . VAL B 1 331 ? -31.813 55.268  26.302  1.00 27.81  ? 331 VAL B CG1 1 
ATOM   6161  C CG2 . VAL B 1 331 ? -31.280 53.622  24.508  1.00 30.35  ? 331 VAL B CG2 1 
ATOM   6162  N N   . ALA B 1 332 ? -27.992 55.729  26.838  1.00 28.16  ? 332 ALA B N   1 
ATOM   6163  C CA  . ALA B 1 332 ? -27.381 56.463  27.926  1.00 27.45  ? 332 ALA B CA  1 
ATOM   6164  C C   . ALA B 1 332 ? -26.724 57.719  27.384  1.00 28.54  ? 332 ALA B C   1 
ATOM   6165  O O   . ALA B 1 332 ? -26.834 58.764  28.023  1.00 34.49  ? 332 ALA B O   1 
ATOM   6166  C CB  . ALA B 1 332 ? -26.406 55.606  28.665  1.00 29.71  ? 332 ALA B CB  1 
ATOM   6167  N N   . GLN B 1 333 ? -26.107 57.631  26.191  1.00 28.51  ? 333 GLN B N   1 
ATOM   6168  C CA  . GLN B 1 333 ? -25.400 58.765  25.607  1.00 28.75  ? 333 GLN B CA  1 
ATOM   6169  C C   . GLN B 1 333 ? -26.358 59.828  25.097  1.00 31.17  ? 333 GLN B C   1 
ATOM   6170  O O   . GLN B 1 333 ? -26.131 61.017  25.313  1.00 30.34  ? 333 GLN B O   1 
ATOM   6171  C CB  . GLN B 1 333 ? -24.487 58.301  24.497  1.00 30.50  ? 333 GLN B CB  1 
ATOM   6172  C CG  . GLN B 1 333 ? -23.317 57.515  25.072  1.00 35.56  ? 333 GLN B CG  1 
ATOM   6173  C CD  . GLN B 1 333 ? -22.336 57.052  24.027  1.00 39.14  ? 333 GLN B CD  1 
ATOM   6174  O OE1 . GLN B 1 333 ? -22.529 56.040  23.331  1.00 41.77  ? 333 GLN B OE1 1 
ATOM   6175  N NE2 . GLN B 1 333 ? -21.244 57.794  23.963  1.00 43.08  ? 333 GLN B NE2 1 
ATOM   6176  N N   . ARG B 1 334 ? -27.439 59.371  24.462  1.00 30.45  ? 334 ARG B N   1 
ATOM   6177  C CA  . ARG B 1 334 ? -28.526 60.238  24.057  1.00 30.73  ? 334 ARG B CA  1 
ATOM   6178  C C   . ARG B 1 334 ? -29.016 61.033  25.262  1.00 29.76  ? 334 ARG B C   1 
ATOM   6179  O O   . ARG B 1 334 ? -29.172 62.252  25.165  1.00 25.70  ? 334 ARG B O   1 
ATOM   6180  C CB  . ARG B 1 334 ? -29.646 59.408  23.415  1.00 31.61  ? 334 ARG B CB  1 
ATOM   6181  C CG  . ARG B 1 334 ? -30.815 60.262  22.947  1.00 32.60  ? 334 ARG B CG  1 
ATOM   6182  C CD  . ARG B 1 334 ? -31.914 59.432  22.294  1.00 31.33  ? 334 ARG B CD  1 
ATOM   6183  N NE  . ARG B 1 334 ? -33.050 60.285  21.939  1.00 32.13  ? 334 ARG B NE  1 
ATOM   6184  C CZ  . ARG B 1 334 ? -33.043 61.321  21.091  1.00 34.75  ? 334 ARG B CZ  1 
ATOM   6185  N NH1 . ARG B 1 334 ? -32.058 61.520  20.236  1.00 32.93  ? 334 ARG B NH1 1 
ATOM   6186  N NH2 . ARG B 1 334 ? -34.079 62.135  21.052  1.00 34.71  ? 334 ARG B NH2 1 
ATOM   6187  N N   . ASP B 1 335 ? -29.232 60.334  26.394  1.00 27.28  ? 335 ASP B N   1 
ATOM   6188  C CA  . ASP B 1 335 ? -29.705 60.998  27.589  1.00 24.54  ? 335 ASP B CA  1 
ATOM   6189  C C   . ASP B 1 335 ? -28.709 62.052  28.041  1.00 25.81  ? 335 ASP B C   1 
ATOM   6190  O O   . ASP B 1 335 ? -29.098 63.145  28.422  1.00 24.81  ? 335 ASP B O   1 
ATOM   6191  C CB  . ASP B 1 335 ? -29.988 60.042  28.725  1.00 26.76  ? 335 ASP B CB  1 
ATOM   6192  C CG  . ASP B 1 335 ? -30.576 60.726  29.957  1.00 31.34  ? 335 ASP B CG  1 
ATOM   6193  O OD1 . ASP B 1 335 ? -31.641 61.413  29.810  1.00 33.08  ? 335 ASP B OD1 1 
ATOM   6194  O OD2 . ASP B 1 335 ? -29.975 60.571  31.052  1.00 30.19  ? 335 ASP B OD2 1 
ATOM   6195  N N   . PHE B 1 336 ? -27.412 61.725  28.025  1.00 28.18  ? 336 PHE B N   1 
ATOM   6196  C CA  . PHE B 1 336 ? -26.417 62.715  28.423  1.00 27.72  ? 336 PHE B CA  1 
ATOM   6197  C C   . PHE B 1 336 ? -26.519 63.948  27.522  1.00 26.10  ? 336 PHE B C   1 
ATOM   6198  O O   . PHE B 1 336 ? -26.406 65.083  27.986  1.00 23.26  ? 336 PHE B O   1 
ATOM   6199  C CB  . PHE B 1 336 ? -25.003 62.118  28.399  1.00 29.91  ? 336 PHE B CB  1 
ATOM   6200  C CG  . PHE B 1 336 ? -23.894 63.079  28.810  1.00 30.61  ? 336 PHE B CG  1 
ATOM   6201  C CD1 . PHE B 1 336 ? -23.301 63.936  27.876  1.00 34.34  ? 336 PHE B CD1 1 
ATOM   6202  C CD2 . PHE B 1 336 ? -23.446 63.131  30.125  1.00 30.49  ? 336 PHE B CD2 1 
ATOM   6203  C CE1 . PHE B 1 336 ? -22.297 64.824  28.242  1.00 31.12  ? 336 PHE B CE1 1 
ATOM   6204  C CE2 . PHE B 1 336 ? -22.454 64.029  30.482  1.00 31.80  ? 336 PHE B CE2 1 
ATOM   6205  C CZ  . PHE B 1 336 ? -21.877 64.864  29.543  1.00 30.43  ? 336 PHE B CZ  1 
ATOM   6206  N N   . ALA B 1 337 ? -26.672 63.712  26.213  1.00 27.05  ? 337 ALA B N   1 
ATOM   6207  C CA  . ALA B 1 337 ? -26.656 64.793  25.241  1.00 30.20  ? 337 ALA B CA  1 
ATOM   6208  C C   . ALA B 1 337 ? -27.872 65.706  25.420  1.00 30.70  ? 337 ALA B C   1 
ATOM   6209  O O   . ALA B 1 337 ? -27.729 66.936  25.374  1.00 33.57  ? 337 ALA B O   1 
ATOM   6210  C CB  . ALA B 1 337 ? -26.602 64.231  23.841  1.00 30.84  ? 337 ALA B CB  1 
ATOM   6211  N N   . LEU B 1 338 ? -29.056 65.104  25.609  1.00 29.13  ? 338 LEU B N   1 
ATOM   6212  C CA  . LEU B 1 338 ? -30.280 65.878  25.758  1.00 34.39  ? 338 LEU B CA  1 
ATOM   6213  C C   . LEU B 1 338 ? -30.136 66.757  27.006  1.00 36.63  ? 338 LEU B C   1 
ATOM   6214  O O   . LEU B 1 338 ? -30.457 67.944  26.998  1.00 44.77  ? 338 LEU B O   1 
ATOM   6215  C CB  . LEU B 1 338 ? -31.514 64.974  25.840  1.00 35.32  ? 338 LEU B CB  1 
ATOM   6216  C CG  . LEU B 1 338 ? -31.939 64.248  24.563  1.00 37.81  ? 338 LEU B CG  1 
ATOM   6217  C CD1 . LEU B 1 338 ? -32.966 63.150  24.855  1.00 36.69  ? 338 LEU B CD1 1 
ATOM   6218  C CD2 . LEU B 1 338 ? -32.478 65.263  23.561  1.00 39.36  ? 338 LEU B CD2 1 
ATOM   6219  N N   . LYS B 1 339 ? -29.586 66.167  28.060  1.00 35.22  ? 339 LYS B N   1 
ATOM   6220  C CA  . LYS B 1 339 ? -29.380 66.849  29.325  1.00 39.91  ? 339 LYS B CA  1 
ATOM   6221  C C   . LYS B 1 339 ? -28.394 68.008  29.184  1.00 35.49  ? 339 LYS B C   1 
ATOM   6222  O O   . LYS B 1 339 ? -28.634 69.059  29.759  1.00 40.44  ? 339 LYS B O   1 
ATOM   6223  C CB  . LYS B 1 339 ? -28.919 65.783  30.327  1.00 45.01  ? 339 LYS B CB  1 
ATOM   6224  C CG  . LYS B 1 339 ? -29.376 65.957  31.751  1.00 54.51  ? 339 LYS B CG  1 
ATOM   6225  C CD  . LYS B 1 339 ? -29.170 64.712  32.617  1.00 63.33  ? 339 LYS B CD  1 
ATOM   6226  C CE  . LYS B 1 339 ? -30.096 63.582  32.243  1.00 66.17  ? 339 LYS B CE  1 
ATOM   6227  N NZ  . LYS B 1 339 ? -30.105 62.502  33.238  1.00 65.00  ? 339 LYS B NZ  1 
ATOM   6228  N N   . HIS B 1 340 ? -27.275 67.826  28.461  1.00 35.71  ? 340 HIS B N   1 
ATOM   6229  C CA  . HIS B 1 340 ? -26.128 68.730  28.607  1.00 35.42  ? 340 HIS B CA  1 
ATOM   6230  C C   . HIS B 1 340 ? -25.718 69.503  27.352  1.00 32.99  ? 340 HIS B C   1 
ATOM   6231  O O   . HIS B 1 340 ? -25.010 70.489  27.495  1.00 33.04  ? 340 HIS B O   1 
ATOM   6232  C CB  . HIS B 1 340 ? -24.856 68.000  29.038  1.00 34.95  ? 340 HIS B CB  1 
ATOM   6233  C CG  . HIS B 1 340 ? -24.956 67.314  30.345  1.00 39.98  ? 340 HIS B CG  1 
ATOM   6234  N ND1 . HIS B 1 340 ? -25.125 67.981  31.537  1.00 47.40  ? 340 HIS B ND1 1 
ATOM   6235  C CD2 . HIS B 1 340 ? -24.905 66.007  30.641  1.00 40.66  ? 340 HIS B CD2 1 
ATOM   6236  C CE1 . HIS B 1 340 ? -25.170 67.087  32.514  1.00 50.96  ? 340 HIS B CE1 1 
ATOM   6237  N NE2 . HIS B 1 340 ? -25.030 65.880  31.986  1.00 44.53  ? 340 HIS B NE2 1 
ATOM   6238  N N   . LEU B 1 341 ? -26.078 69.040  26.143  1.00 37.20  ? 341 LEU B N   1 
ATOM   6239  C CA  . LEU B 1 341 ? -25.745 69.764  24.922  1.00 38.17  ? 341 LEU B CA  1 
ATOM   6240  C C   . LEU B 1 341 ? -26.845 69.636  23.860  1.00 39.89  ? 341 LEU B C   1 
ATOM   6241  O O   . LEU B 1 341 ? -26.555 69.439  22.685  1.00 41.15  ? 341 LEU B O   1 
ATOM   6242  C CB  . LEU B 1 341 ? -24.409 69.239  24.405  1.00 37.26  ? 341 LEU B CB  1 
ATOM   6243  C CG  . LEU B 1 341 ? -24.352 67.730  24.133  1.00 36.46  ? 341 LEU B CG  1 
ATOM   6244  C CD1 . LEU B 1 341 ? -23.730 67.438  22.789  1.00 35.73  ? 341 LEU B CD1 1 
ATOM   6245  C CD2 . LEU B 1 341 ? -23.550 67.033  25.195  1.00 38.53  ? 341 LEU B CD2 1 
ATOM   6246  N N   . PRO B 1 342 ? -28.143 69.834  24.182  1.00 45.34  ? 342 PRO B N   1 
ATOM   6247  C CA  . PRO B 1 342 ? -29.201 69.613  23.189  1.00 43.64  ? 342 PRO B CA  1 
ATOM   6248  C C   . PRO B 1 342 ? -29.179 70.485  21.931  1.00 44.27  ? 342 PRO B C   1 
ATOM   6249  O O   . PRO B 1 342 ? -29.785 70.125  20.926  1.00 40.48  ? 342 PRO B O   1 
ATOM   6250  C CB  . PRO B 1 342 ? -30.493 69.827  23.999  1.00 41.85  ? 342 PRO B CB  1 
ATOM   6251  C CG  . PRO B 1 342 ? -30.070 70.737  25.136  1.00 45.69  ? 342 PRO B CG  1 
ATOM   6252  C CD  . PRO B 1 342 ? -28.657 70.293  25.488  1.00 47.75  ? 342 PRO B CD  1 
ATOM   6253  N N   . ASP B 1 343 ? -28.491 71.629  21.966  1.00 45.96  ? 343 ASP B N   1 
ATOM   6254  C CA  . ASP B 1 343 ? -28.488 72.539  20.827  1.00 46.75  ? 343 ASP B CA  1 
ATOM   6255  C C   . ASP B 1 343 ? -27.266 72.371  19.922  1.00 41.50  ? 343 ASP B C   1 
ATOM   6256  O O   . ASP B 1 343 ? -27.090 73.107  18.957  1.00 44.24  ? 343 ASP B O   1 
ATOM   6257  C CB  . ASP B 1 343 ? -28.551 73.980  21.301  1.00 52.01  ? 343 ASP B CB  1 
ATOM   6258  C CG  . ASP B 1 343 ? -29.826 74.335  22.035  1.00 54.36  ? 343 ASP B CG  1 
ATOM   6259  O OD1 . ASP B 1 343 ? -30.882 73.778  21.667  1.00 62.21  ? 343 ASP B OD1 1 
ATOM   6260  O OD2 . ASP B 1 343 ? -29.747 75.189  22.928  1.00 57.09  ? 343 ASP B OD2 1 
ATOM   6261  N N   . ASP B 1 344 ? -26.387 71.430  20.239  1.00 39.58  ? 344 ASP B N   1 
ATOM   6262  C CA  . ASP B 1 344 ? -25.242 71.184  19.388  1.00 38.49  ? 344 ASP B CA  1 
ATOM   6263  C C   . ASP B 1 344 ? -25.719 70.696  18.021  1.00 35.39  ? 344 ASP B C   1 
ATOM   6264  O O   . ASP B 1 344 ? -26.532 69.794  17.906  1.00 32.47  ? 344 ASP B O   1 
ATOM   6265  C CB  . ASP B 1 344 ? -24.324 70.189  20.059  1.00 38.12  ? 344 ASP B CB  1 
ATOM   6266  C CG  . ASP B 1 344 ? -23.022 69.952  19.336  1.00 37.68  ? 344 ASP B CG  1 
ATOM   6267  O OD1 . ASP B 1 344 ? -23.059 69.199  18.344  1.00 35.12  ? 344 ASP B OD1 1 
ATOM   6268  O OD2 . ASP B 1 344 ? -22.023 70.563  19.774  1.00 38.88  ? 344 ASP B OD2 1 
ATOM   6269  N N   . GLU B 1 345 ? -25.192 71.288  16.964  1.00 36.92  ? 345 GLU B N   1 
ATOM   6270  C CA  . GLU B 1 345 ? -25.706 71.008  15.641  1.00 39.54  ? 345 GLU B CA  1 
ATOM   6271  C C   . GLU B 1 345 ? -25.331 69.600  15.184  1.00 39.27  ? 345 GLU B C   1 
ATOM   6272  O O   . GLU B 1 345 ? -26.131 68.946  14.520  1.00 39.11  ? 345 GLU B O   1 
ATOM   6273  C CB  . GLU B 1 345 ? -25.277 72.146  14.729  1.00 44.39  ? 345 GLU B CB  1 
ATOM   6274  C CG  . GLU B 1 345 ? -25.979 73.453  15.094  1.00 48.27  ? 345 GLU B CG  1 
ATOM   6275  C CD  . GLU B 1 345 ? -26.425 74.127  13.818  1.00 59.09  ? 345 GLU B CD  1 
ATOM   6276  O OE1 . GLU B 1 345 ? -27.636 74.382  13.641  1.00 68.65  ? 345 GLU B OE1 1 
ATOM   6277  O OE2 . GLU B 1 345 ? -25.543 74.320  12.960  1.00 60.82  ? 345 GLU B OE2 1 
ATOM   6278  N N   . LEU B 1 346 ? -24.145 69.104  15.555  1.00 38.55  ? 346 LEU B N   1 
ATOM   6279  C CA  . LEU B 1 346 ? -23.780 67.738  15.205  1.00 34.03  ? 346 LEU B CA  1 
ATOM   6280  C C   . LEU B 1 346 ? -24.673 66.783  15.998  1.00 31.10  ? 346 LEU B C   1 
ATOM   6281  O O   . LEU B 1 346 ? -25.096 65.749  15.494  1.00 32.78  ? 346 LEU B O   1 
ATOM   6282  C CB  . LEU B 1 346 ? -22.285 67.464  15.417  1.00 34.65  ? 346 LEU B CB  1 
ATOM   6283  C CG  . LEU B 1 346 ? -21.313 68.305  14.574  1.00 37.26  ? 346 LEU B CG  1 
ATOM   6284  C CD1 . LEU B 1 346 ? -19.872 67.922  14.770  1.00 35.28  ? 346 LEU B CD1 1 
ATOM   6285  C CD2 . LEU B 1 346 ? -21.628 68.204  13.088  1.00 37.41  ? 346 LEU B CD2 1 
ATOM   6286  N N   . PHE B 1 347 ? -25.001 67.128  17.244  1.00 29.96  ? 347 PHE B N   1 
ATOM   6287  C CA  . PHE B 1 347 ? -25.893 66.266  17.998  1.00 30.31  ? 347 PHE B CA  1 
ATOM   6288  C C   . PHE B 1 347 ? -27.251 66.172  17.297  1.00 30.48  ? 347 PHE B C   1 
ATOM   6289  O O   . PHE B 1 347 ? -27.832 65.088  17.178  1.00 29.46  ? 347 PHE B O   1 
ATOM   6290  C CB  . PHE B 1 347 ? -26.051 66.746  19.444  1.00 29.71  ? 347 PHE B CB  1 
ATOM   6291  C CG  . PHE B 1 347 ? -27.158 65.977  20.142  1.00 31.00  ? 347 PHE B CG  1 
ATOM   6292  C CD1 . PHE B 1 347 ? -27.207 64.588  20.090  1.00 33.42  ? 347 PHE B CD1 1 
ATOM   6293  C CD2 . PHE B 1 347 ? -28.201 66.643  20.764  1.00 34.04  ? 347 PHE B CD2 1 
ATOM   6294  C CE1 . PHE B 1 347 ? -28.243 63.884  20.698  1.00 35.56  ? 347 PHE B CE1 1 
ATOM   6295  C CE2 . PHE B 1 347 ? -29.239 65.936  21.353  1.00 36.68  ? 347 PHE B CE2 1 
ATOM   6296  C CZ  . PHE B 1 347 ? -29.251 64.557  21.332  1.00 35.06  ? 347 PHE B CZ  1 
ATOM   6297  N N   . LYS B 1 348 ? -27.746 67.327  16.831  1.00 33.37  ? 348 LYS B N   1 
ATOM   6298  C CA  . LYS B 1 348 ? -29.039 67.438  16.180  1.00 32.69  ? 348 LYS B CA  1 
ATOM   6299  C C   . LYS B 1 348 ? -29.163 66.439  15.041  1.00 30.77  ? 348 LYS B C   1 
ATOM   6300  O O   . LYS B 1 348 ? -30.248 65.897  14.805  1.00 30.80  ? 348 LYS B O   1 
ATOM   6301  C CB  . LYS B 1 348 ? -29.289 68.883  15.750  1.00 36.74  ? 348 LYS B CB  1 
ATOM   6302  C CG  . LYS B 1 348 ? -29.851 69.697  16.901  1.00 42.84  ? 348 LYS B CG  1 
ATOM   6303  C CD  . LYS B 1 348 ? -29.985 71.187  16.615  1.00 53.13  ? 348 LYS B CD  1 
ATOM   6304  C CE  . LYS B 1 348 ? -30.915 71.851  17.587  1.00 60.51  ? 348 LYS B CE  1 
ATOM   6305  N NZ  . LYS B 1 348 ? -30.874 73.304  17.404  1.00 62.58  ? 348 LYS B NZ  1 
ATOM   6306  N N   . ILE B 1 349 ? -28.038 66.158  14.388  1.00 28.23  ? 349 ILE B N   1 
ATOM   6307  C CA  . ILE B 1 349 ? -28.043 65.254  13.261  1.00 28.92  ? 349 ILE B CA  1 
ATOM   6308  C C   . ILE B 1 349 ? -28.090 63.818  13.754  1.00 29.66  ? 349 ILE B C   1 
ATOM   6309  O O   . ILE B 1 349 ? -28.768 62.980  13.158  1.00 31.94  ? 349 ILE B O   1 
ATOM   6310  C CB  . ILE B 1 349 ? -26.824 65.517  12.371  1.00 28.55  ? 349 ILE B CB  1 
ATOM   6311  C CG1 . ILE B 1 349 ? -26.845 66.948  11.869  1.00 29.19  ? 349 ILE B CG1 1 
ATOM   6312  C CG2 . ILE B 1 349 ? -26.743 64.499  11.235  1.00 28.94  ? 349 ILE B CG2 1 
ATOM   6313  C CD1 . ILE B 1 349 ? -25.706 67.284  10.928  1.00 31.83  ? 349 ILE B CD1 1 
ATOM   6314  N N   . VAL B 1 350 ? -27.286 63.532  14.777  1.00 29.86  ? 350 VAL B N   1 
ATOM   6315  C CA  . VAL B 1 350 ? -27.310 62.244  15.447  1.00 30.84  ? 350 VAL B CA  1 
ATOM   6316  C C   . VAL B 1 350 ? -28.725 61.957  15.957  1.00 33.65  ? 350 VAL B C   1 
ATOM   6317  O O   . VAL B 1 350 ? -29.189 60.819  15.885  1.00 33.53  ? 350 VAL B O   1 
ATOM   6318  C CB  . VAL B 1 350 ? -26.285 62.243  16.597  1.00 29.69  ? 350 VAL B CB  1 
ATOM   6319  C CG1 . VAL B 1 350 ? -26.599 61.203  17.659  1.00 29.14  ? 350 VAL B CG1 1 
ATOM   6320  C CG2 . VAL B 1 350 ? -24.865 62.083  16.086  1.00 30.12  ? 350 VAL B CG2 1 
ATOM   6321  N N   . SER B 1 351 ? -29.393 62.988  16.501  1.00 34.12  ? 351 SER B N   1 
ATOM   6322  C CA  . SER B 1 351 ? -30.740 62.832  17.038  1.00 33.88  ? 351 SER B CA  1 
ATOM   6323  C C   . SER B 1 351 ? -31.736 62.555  15.919  1.00 33.44  ? 351 SER B C   1 
ATOM   6324  O O   . SER B 1 351 ? -32.534 61.631  16.031  1.00 34.07  ? 351 SER B O   1 
ATOM   6325  C CB  . SER B 1 351 ? -31.171 64.028  17.845  1.00 36.38  ? 351 SER B CB  1 
ATOM   6326  O OG  . SER B 1 351 ? -32.467 63.827  18.390  1.00 35.85  ? 351 SER B OG  1 
ATOM   6327  N N   . LEU B 1 352 ? -31.679 63.356  14.846  1.00 34.22  ? 352 LEU B N   1 
ATOM   6328  C CA  . LEU B 1 352 ? -32.564 63.171  13.707  1.00 35.87  ? 352 LEU B CA  1 
ATOM   6329  C C   . LEU B 1 352 ? -32.405 61.775  13.093  1.00 35.09  ? 352 LEU B C   1 
ATOM   6330  O O   . LEU B 1 352 ? -33.392 61.135  12.737  1.00 36.91  ? 352 LEU B O   1 
ATOM   6331  C CB  . LEU B 1 352 ? -32.308 64.276  12.691  1.00 38.26  ? 352 LEU B CB  1 
ATOM   6332  C CG  . LEU B 1 352 ? -33.270 64.347  11.499  1.00 39.71  ? 352 LEU B CG  1 
ATOM   6333  C CD1 . LEU B 1 352 ? -34.655 64.825  11.936  1.00 38.01  ? 352 LEU B CD1 1 
ATOM   6334  C CD2 . LEU B 1 352 ? -32.672 65.264  10.450  1.00 37.00  ? 352 LEU B CD2 1 
ATOM   6335  N N   . CYS B 1 353 ? -31.168 61.287  12.987  1.00 34.02  ? 353 CYS B N   1 
ATOM   6336  C CA  . CYS B 1 353 ? -30.913 59.937  12.504  1.00 31.93  ? 353 CYS B CA  1 
ATOM   6337  C C   . CYS B 1 353 ? -31.612 58.883  13.363  1.00 32.00  ? 353 CYS B C   1 
ATOM   6338  O O   . CYS B 1 353 ? -32.106 57.895  12.823  1.00 34.05  ? 353 CYS B O   1 
ATOM   6339  C CB  . CYS B 1 353 ? -29.423 59.614  12.490  1.00 33.63  ? 353 CYS B CB  1 
ATOM   6340  S SG  . CYS B 1 353 ? -28.461 60.467  11.208  1.00 35.52  ? 353 CYS B SG  1 
ATOM   6341  N N   . TYR B 1 354 ? -31.633 59.066  14.690  1.00 29.93  ? 354 TYR B N   1 
ATOM   6342  C CA  . TYR B 1 354 ? -32.298 58.120  15.580  1.00 32.17  ? 354 TYR B CA  1 
ATOM   6343  C C   . TYR B 1 354 ? -33.774 57.959  15.195  1.00 32.79  ? 354 TYR B C   1 
ATOM   6344  O O   . TYR B 1 354 ? -34.319 56.869  15.270  1.00 33.83  ? 354 TYR B O   1 
ATOM   6345  C CB  . TYR B 1 354 ? -32.208 58.584  17.043  1.00 32.11  ? 354 TYR B CB  1 
ATOM   6346  C CG  . TYR B 1 354 ? -32.617 57.578  18.121  1.00 33.23  ? 354 TYR B CG  1 
ATOM   6347  C CD1 . TYR B 1 354 ? -32.434 56.201  17.977  1.00 33.16  ? 354 TYR B CD1 1 
ATOM   6348  C CD2 . TYR B 1 354 ? -33.179 58.020  19.313  1.00 37.44  ? 354 TYR B CD2 1 
ATOM   6349  C CE1 . TYR B 1 354 ? -32.798 55.309  18.977  1.00 34.61  ? 354 TYR B CE1 1 
ATOM   6350  C CE2 . TYR B 1 354 ? -33.553 57.141  20.320  1.00 37.75  ? 354 TYR B CE2 1 
ATOM   6351  C CZ  . TYR B 1 354 ? -33.344 55.782  20.166  1.00 38.57  ? 354 TYR B CZ  1 
ATOM   6352  O OH  . TYR B 1 354 ? -33.705 54.960  21.213  1.00 39.11  ? 354 TYR B OH  1 
ATOM   6353  N N   . GLU B 1 355 ? -34.420 59.066  14.813  1.00 37.13  ? 355 GLU B N   1 
ATOM   6354  C CA  . GLU B 1 355 ? -35.802 59.069  14.360  1.00 40.54  ? 355 GLU B CA  1 
ATOM   6355  C C   . GLU B 1 355 ? -35.909 58.436  12.965  1.00 43.96  ? 355 GLU B C   1 
ATOM   6356  O O   . GLU B 1 355 ? -36.789 57.609  12.720  1.00 42.51  ? 355 GLU B O   1 
ATOM   6357  C CB  . GLU B 1 355 ? -36.294 60.518  14.407  1.00 41.55  ? 355 GLU B CB  1 
ATOM   6358  C CG  . GLU B 1 355 ? -37.772 60.710  14.061  1.00 45.15  ? 355 GLU B CG  1 
ATOM   6359  C CD  . GLU B 1 355 ? -38.257 62.163  14.066  1.00 46.53  ? 355 GLU B CD  1 
ATOM   6360  O OE1 . GLU B 1 355 ? -39.428 62.358  13.636  1.00 45.61  ? 355 GLU B OE1 1 
ATOM   6361  O OE2 . GLU B 1 355 ? -37.502 63.086  14.507  1.00 42.12  ? 355 GLU B OE2 1 
ATOM   6362  N N   . VAL B 1 356 ? -35.009 58.800  12.045  1.00 35.36  ? 356 VAL B N   1 
ATOM   6363  C CA  . VAL B 1 356 ? -35.283 58.563  10.641  1.00 36.65  ? 356 VAL B CA  1 
ATOM   6364  C C   . VAL B 1 356 ? -34.735 57.219  10.186  1.00 38.78  ? 356 VAL B C   1 
ATOM   6365  O O   . VAL B 1 356 ? -35.449 56.482  9.506   1.00 36.50  ? 356 VAL B O   1 
ATOM   6366  C CB  . VAL B 1 356 ? -34.727 59.687  9.754   1.00 39.81  ? 356 VAL B CB  1 
ATOM   6367  C CG1 . VAL B 1 356 ? -34.545 59.240  8.297   1.00 39.35  ? 356 VAL B CG1 1 
ATOM   6368  C CG2 . VAL B 1 356 ? -35.588 60.943  9.870   1.00 39.36  ? 356 VAL B CG2 1 
ATOM   6369  N N   . ILE B 1 357 ? -33.467 56.942  10.525  1.00 34.54  ? 357 ILE B N   1 
ATOM   6370  C CA  . ILE B 1 357 ? -32.727 55.870  9.887   1.00 34.59  ? 357 ILE B CA  1 
ATOM   6371  C C   . ILE B 1 357 ? -33.349 54.513  10.219  1.00 34.44  ? 357 ILE B C   1 
ATOM   6372  O O   . ILE B 1 357 ? -33.451 53.667  9.330   1.00 35.48  ? 357 ILE B O   1 
ATOM   6373  C CB  . ILE B 1 357 ? -31.219 55.919  10.244  1.00 37.08  ? 357 ILE B CB  1 
ATOM   6374  C CG1 . ILE B 1 357 ? -30.559 57.220  9.819   1.00 37.87  ? 357 ILE B CG1 1 
ATOM   6375  C CG2 . ILE B 1 357 ? -30.451 54.723  9.668   1.00 34.78  ? 357 ILE B CG2 1 
ATOM   6376  C CD1 . ILE B 1 357 ? -30.475 57.417  8.321   1.00 38.88  ? 357 ILE B CD1 1 
ATOM   6377  N N   . PRO B 1 358 ? -33.746 54.215  11.479  1.00 36.16  ? 358 PRO B N   1 
ATOM   6378  C CA  . PRO B 1 358 ? -34.435 52.956  11.768  1.00 41.48  ? 358 PRO B CA  1 
ATOM   6379  C C   . PRO B 1 358 ? -35.744 52.728  10.989  1.00 44.08  ? 358 PRO B C   1 
ATOM   6380  O O   . PRO B 1 358 ? -36.134 51.577  10.783  1.00 47.04  ? 358 PRO B O   1 
ATOM   6381  C CB  . PRO B 1 358 ? -34.661 52.958  13.306  1.00 39.18  ? 358 PRO B CB  1 
ATOM   6382  C CG  . PRO B 1 358 ? -33.731 54.034  13.825  1.00 38.44  ? 358 PRO B CG  1 
ATOM   6383  C CD  . PRO B 1 358 ? -33.554 55.033  12.684  1.00 38.50  ? 358 PRO B CD  1 
ATOM   6384  N N   . GLU B 1 359 ? -36.432 53.794  10.557  1.00 42.21  ? 359 GLU B N   1 
ATOM   6385  C CA  . GLU B 1 359 ? -37.627 53.631  9.727   1.00 48.03  ? 359 GLU B CA  1 
ATOM   6386  C C   . GLU B 1 359 ? -37.203 53.220  8.315   1.00 47.10  ? 359 GLU B C   1 
ATOM   6387  O O   . GLU B 1 359 ? -37.693 52.226  7.763   1.00 41.51  ? 359 GLU B O   1 
ATOM   6388  C CB  . GLU B 1 359 ? -38.557 54.851  9.659   1.00 55.86  ? 359 GLU B CB  1 
ATOM   6389  C CG  . GLU B 1 359 ? -39.480 55.024  10.872  1.00 62.81  ? 359 GLU B CG  1 
ATOM   6390  C CD  . GLU B 1 359 ? -40.260 53.798  11.377  1.00 68.35  ? 359 GLU B CD  1 
ATOM   6391  O OE1 . GLU B 1 359 ? -40.231 53.663  12.618  1.00 75.05  ? 359 GLU B OE1 1 
ATOM   6392  O OE2 . GLU B 1 359 ? -40.866 52.975  10.629  1.00 57.60  ? 359 GLU B OE2 1 
ATOM   6393  N N   . VAL B 1 360 ? -36.247 53.968  7.754   1.00 44.01  ? 360 VAL B N   1 
ATOM   6394  C CA  . VAL B 1 360 ? -35.706 53.665  6.440   1.00 41.92  ? 360 VAL B CA  1 
ATOM   6395  C C   . VAL B 1 360 ? -35.162 52.236  6.415   1.00 42.28  ? 360 VAL B C   1 
ATOM   6396  O O   . VAL B 1 360 ? -35.426 51.510  5.466   1.00 47.23  ? 360 VAL B O   1 
ATOM   6397  C CB  . VAL B 1 360 ? -34.639 54.696  6.036   1.00 36.99  ? 360 VAL B CB  1 
ATOM   6398  C CG1 . VAL B 1 360 ? -33.937 54.328  4.742   1.00 33.81  ? 360 VAL B CG1 1 
ATOM   6399  C CG2 . VAL B 1 360 ? -35.237 56.091  5.925   1.00 36.80  ? 360 VAL B CG2 1 
ATOM   6400  N N   . LEU B 1 361 ? -34.462 51.809  7.468   1.00 42.62  ? 361 LEU B N   1 
ATOM   6401  C CA  . LEU B 1 361 ? -33.804 50.510  7.451   1.00 48.30  ? 361 LEU B CA  1 
ATOM   6402  C C   . LEU B 1 361 ? -34.804 49.353  7.524   1.00 50.79  ? 361 LEU B C   1 
ATOM   6403  O O   . LEU B 1 361 ? -34.524 48.293  6.977   1.00 50.92  ? 361 LEU B O   1 
ATOM   6404  C CB  . LEU B 1 361 ? -32.769 50.408  8.575   1.00 51.27  ? 361 LEU B CB  1 
ATOM   6405  C CG  . LEU B 1 361 ? -31.333 50.812  8.226   1.00 47.43  ? 361 LEU B CG  1 
ATOM   6406  C CD1 . LEU B 1 361 ? -30.451 50.932  9.467   1.00 45.89  ? 361 LEU B CD1 1 
ATOM   6407  C CD2 . LEU B 1 361 ? -30.736 49.830  7.239   1.00 45.81  ? 361 LEU B CD2 1 
ATOM   6408  N N   . LYS B 1 362 ? -35.919 49.526  8.251   1.00 58.80  ? 362 LYS B N   1 
ATOM   6409  C CA  . LYS B 1 362 ? -36.979 48.522  8.317   1.00 64.79  ? 362 LYS B CA  1 
ATOM   6410  C C   . LYS B 1 362 ? -37.635 48.373  6.945   1.00 65.03  ? 362 LYS B C   1 
ATOM   6411  O O   . LYS B 1 362 ? -37.882 47.265  6.473   1.00 64.16  ? 362 LYS B O   1 
ATOM   6412  C CB  . LYS B 1 362 ? -38.093 48.883  9.311   1.00 68.20  ? 362 LYS B CB  1 
ATOM   6413  C CG  . LYS B 1 362 ? -38.032 48.247  10.694  1.00 72.74  ? 362 LYS B CG  1 
ATOM   6414  C CD  . LYS B 1 362 ? -38.831 49.038  11.726  1.00 82.02  ? 362 LYS B CD  1 
ATOM   6415  C CE  . LYS B 1 362 ? -38.707 48.481  13.117  1.00 86.24  ? 362 LYS B CE  1 
ATOM   6416  N NZ  . LYS B 1 362 ? -39.283 49.388  14.115  1.00 87.46  ? 362 LYS B NZ  1 
ATOM   6417  N N   . LYS B 1 363 ? -37.921 49.521  6.326   1.00 62.24  ? 363 LYS B N   1 
ATOM   6418  C CA  . LYS B 1 363 ? -38.591 49.586  5.043   1.00 57.02  ? 363 LYS B CA  1 
ATOM   6419  C C   . LYS B 1 363 ? -37.657 49.195  3.897   1.00 62.48  ? 363 LYS B C   1 
ATOM   6420  O O   . LYS B 1 363 ? -38.139 48.807  2.836   1.00 63.40  ? 363 LYS B O   1 
ATOM   6421  C CB  . LYS B 1 363 ? -39.152 50.999  4.897   1.00 57.97  ? 363 LYS B CB  1 
ATOM   6422  C CG  . LYS B 1 363 ? -40.355 51.248  5.789   1.00 62.60  ? 363 LYS B CG  1 
ATOM   6423  C CD  . LYS B 1 363 ? -40.805 52.700  5.770   1.00 68.73  ? 363 LYS B CD  1 
ATOM   6424  C CE  . LYS B 1 363 ? -41.952 52.923  6.701   1.00 79.69  ? 363 LYS B CE  1 
ATOM   6425  N NZ  . LYS B 1 363 ? -42.125 54.362  6.913   1.00 85.17  ? 363 LYS B NZ  1 
ATOM   6426  N N   . HIS B 1 364 ? -36.334 49.290  4.098   1.00 61.18  ? 364 HIS B N   1 
ATOM   6427  C CA  . HIS B 1 364 ? -35.383 48.827  3.100   1.00 61.31  ? 364 HIS B CA  1 
ATOM   6428  C C   . HIS B 1 364 ? -35.419 47.298  3.077   1.00 67.41  ? 364 HIS B C   1 
ATOM   6429  O O   . HIS B 1 364 ? -35.111 46.683  2.053   1.00 89.09  ? 364 HIS B O   1 
ATOM   6430  C CB  . HIS B 1 364 ? -34.011 49.480  3.326   1.00 63.99  ? 364 HIS B CB  1 
ATOM   6431  C CG  . HIS B 1 364 ? -32.989 49.213  2.266   1.00 58.91  ? 364 HIS B CG  1 
ATOM   6432  N ND1 . HIS B 1 364 ? -32.867 49.914  1.080   1.00 52.93  ? 364 HIS B ND1 1 
ATOM   6433  C CD2 . HIS B 1 364 ? -32.022 48.287  2.255   1.00 55.85  ? 364 HIS B CD2 1 
ATOM   6434  C CE1 . HIS B 1 364 ? -31.872 49.395  0.365   1.00 51.46  ? 364 HIS B CE1 1 
ATOM   6435  N NE2 . HIS B 1 364 ? -31.340 48.409  1.065   1.00 54.88  ? 364 HIS B NE2 1 
ATOM   6436  N N   . GLY B 1 365 ? -35.815 46.696  4.207   1.00 70.68  ? 365 GLY B N   1 
ATOM   6437  C CA  . GLY B 1 365 ? -36.160 45.283  4.270   1.00 83.31  ? 365 GLY B CA  1 
ATOM   6438  C C   . GLY B 1 365 ? -34.951 44.393  4.557   1.00 102.64 ? 365 GLY B C   1 
ATOM   6439  O O   . GLY B 1 365 ? -35.130 43.200  4.805   1.00 102.22 ? 365 GLY B O   1 
ATOM   6440  N N   . LYS B 1 366 ? -33.742 44.987  4.533   1.00 123.36 ? 366 LYS B N   1 
ATOM   6441  C CA  . LYS B 1 366 ? -32.480 44.261  4.618   1.00 130.07 ? 366 LYS B CA  1 
ATOM   6442  C C   . LYS B 1 366 ? -32.251 43.776  6.048   1.00 136.63 ? 366 LYS B C   1 
ATOM   6443  O O   . LYS B 1 366 ? -32.161 42.573  6.283   1.00 135.46 ? 366 LYS B O   1 
ATOM   6444  C CB  . LYS B 1 366 ? -31.247 45.091  4.220   1.00 132.26 ? 366 LYS B CB  1 
ATOM   6445  C CG  . LYS B 1 366 ? -30.971 45.329  2.728   1.00 137.18 ? 366 LYS B CG  1 
ATOM   6446  C CD  . LYS B 1 366 ? -30.447 44.151  1.915   1.00 133.32 ? 366 LYS B CD  1 
ATOM   6447  C CE  . LYS B 1 366 ? -31.546 43.322  1.314   1.00 130.16 ? 366 LYS B CE  1 
ATOM   6448  N NZ  . LYS B 1 366 ? -31.036 42.033  0.839   1.00 127.20 ? 366 LYS B NZ  1 
ATOM   6449  N N   . ALA B 1 367 ? -32.162 44.723  6.993   1.00 142.14 ? 367 ALA B N   1 
ATOM   6450  C CA  . ALA B 1 367 ? -31.595 44.460  8.310   1.00 143.28 ? 367 ALA B CA  1 
ATOM   6451  C C   . ALA B 1 367 ? -32.670 44.036  9.323   1.00 128.24 ? 367 ALA B C   1 
ATOM   6452  O O   . ALA B 1 367 ? -33.737 44.652  9.405   1.00 104.09 ? 367 ALA B O   1 
ATOM   6453  C CB  . ALA B 1 367 ? -30.829 45.687  8.770   1.00 146.35 ? 367 ALA B CB  1 
ATOM   6454  N N   . LYS B 1 368 ? -32.369 42.975  10.098  1.00 114.85 ? 368 LYS B N   1 
ATOM   6455  C CA  . LYS B 1 368 ? -33.223 42.505  11.186  1.00 98.54  ? 368 LYS B CA  1 
ATOM   6456  C C   . LYS B 1 368 ? -32.993 43.376  12.426  1.00 87.02  ? 368 LYS B C   1 
ATOM   6457  O O   . LYS B 1 368 ? -33.823 43.400  13.337  1.00 79.30  ? 368 LYS B O   1 
ATOM   6458  C CB  . LYS B 1 368 ? -32.996 41.012  11.474  1.00 86.42  ? 368 LYS B CB  1 
ATOM   6459  N N   . ASN B 1 369 ? -31.841 44.069  12.457  1.00 74.36  ? 369 ASN B N   1 
ATOM   6460  C CA  . ASN B 1 369 ? -31.595 45.162  13.385  1.00 63.13  ? 369 ASN B CA  1 
ATOM   6461  C C   . ASN B 1 369 ? -31.526 46.477  12.621  1.00 53.84  ? 369 ASN B C   1 
ATOM   6462  O O   . ASN B 1 369 ? -30.547 46.746  11.942  1.00 59.08  ? 369 ASN B O   1 
ATOM   6463  C CB  . ASN B 1 369 ? -30.269 45.030  14.128  1.00 64.53  ? 369 ASN B CB  1 
ATOM   6464  C CG  . ASN B 1 369 ? -30.054 46.119  15.162  1.00 62.50  ? 369 ASN B CG  1 
ATOM   6465  O OD1 . ASN B 1 369 ? -30.983 46.845  15.529  1.00 62.42  ? 369 ASN B OD1 1 
ATOM   6466  N ND2 . ASN B 1 369 ? -28.836 46.255  15.659  1.00 66.11  ? 369 ASN B ND2 1 
ATOM   6467  N N   . PRO B 1 370 ? -32.552 47.345  12.686  1.00 47.85  ? 370 PRO B N   1 
ATOM   6468  C CA  . PRO B 1 370 ? -32.422 48.686  12.126  1.00 42.64  ? 370 PRO B CA  1 
ATOM   6469  C C   . PRO B 1 370 ? -31.800 49.718  13.054  1.00 39.68  ? 370 PRO B C   1 
ATOM   6470  O O   . PRO B 1 370 ? -31.800 50.892  12.703  1.00 36.63  ? 370 PRO B O   1 
ATOM   6471  C CB  . PRO B 1 370 ? -33.904 48.996  11.825  1.00 39.88  ? 370 PRO B CB  1 
ATOM   6472  C CG  . PRO B 1 370 ? -34.640 48.381  12.972  1.00 42.32  ? 370 PRO B CG  1 
ATOM   6473  C CD  . PRO B 1 370 ? -33.912 47.056  13.178  1.00 48.31  ? 370 PRO B CD  1 
ATOM   6474  N N   . TRP B 1 371 ? -31.290 49.285  14.222  1.00 40.38  ? 371 TRP B N   1 
ATOM   6475  C CA  . TRP B 1 371 ? -31.068 50.195  15.343  1.00 39.83  ? 371 TRP B CA  1 
ATOM   6476  C C   . TRP B 1 371 ? -29.581 50.522  15.545  1.00 36.82  ? 371 TRP B C   1 
ATOM   6477  O O   . TRP B 1 371 ? -28.705 49.755  15.142  1.00 33.25  ? 371 TRP B O   1 
ATOM   6478  C CB  . TRP B 1 371 ? -31.688 49.648  16.642  1.00 41.22  ? 371 TRP B CB  1 
ATOM   6479  C CG  . TRP B 1 371 ? -33.178 49.403  16.613  1.00 38.45  ? 371 TRP B CG  1 
ATOM   6480  C CD1 . TRP B 1 371 ? -33.809 48.192  16.539  1.00 36.73  ? 371 TRP B CD1 1 
ATOM   6481  C CD2 . TRP B 1 371 ? -34.222 50.397  16.670  1.00 37.18  ? 371 TRP B CD2 1 
ATOM   6482  N NE1 . TRP B 1 371 ? -35.166 48.363  16.551  1.00 39.11  ? 371 TRP B NE1 1 
ATOM   6483  C CE2 . TRP B 1 371 ? -35.450 49.703  16.618  1.00 38.89  ? 371 TRP B CE2 1 
ATOM   6484  C CE3 . TRP B 1 371 ? -34.243 51.792  16.737  1.00 37.32  ? 371 TRP B CE3 1 
ATOM   6485  C CZ2 . TRP B 1 371 ? -36.674 50.364  16.628  1.00 36.87  ? 371 TRP B CZ2 1 
ATOM   6486  C CZ3 . TRP B 1 371 ? -35.456 52.443  16.751  1.00 36.34  ? 371 TRP B CZ3 1 
ATOM   6487  C CH2 . TRP B 1 371 ? -36.653 51.741  16.674  1.00 34.94  ? 371 TRP B CH2 1 
ATOM   6488  N N   . PRO B 1 372 ? -29.269 51.682  16.185  1.00 33.64  ? 372 PRO B N   1 
ATOM   6489  C CA  . PRO B 1 372 ? -27.894 52.156  16.342  1.00 33.52  ? 372 PRO B CA  1 
ATOM   6490  C C   . PRO B 1 372 ? -27.119 51.472  17.454  1.00 32.24  ? 372 PRO B C   1 
ATOM   6491  O O   . PRO B 1 372 ? -27.730 50.835  18.289  1.00 29.76  ? 372 PRO B O   1 
ATOM   6492  C CB  . PRO B 1 372 ? -28.094 53.640  16.646  1.00 34.88  ? 372 PRO B CB  1 
ATOM   6493  C CG  . PRO B 1 372 ? -29.417 53.712  17.368  1.00 35.57  ? 372 PRO B CG  1 
ATOM   6494  C CD  . PRO B 1 372 ? -30.247 52.626  16.748  1.00 33.78  ? 372 PRO B CD  1 
ATOM   6495  N N   . ASN B 1 373 ? -25.781 51.595  17.460  1.00 33.70  ? 373 ASN B N   1 
ATOM   6496  C CA  . ASN B 1 373 ? -25.000 51.102  18.593  1.00 35.43  ? 373 ASN B CA  1 
ATOM   6497  C C   . ASN B 1 373 ? -24.209 52.249  19.213  1.00 32.74  ? 373 ASN B C   1 
ATOM   6498  O O   . ASN B 1 373 ? -24.400 53.403  18.837  1.00 31.30  ? 373 ASN B O   1 
ATOM   6499  C CB  . ASN B 1 373 ? -24.133 49.901  18.236  1.00 37.15  ? 373 ASN B CB  1 
ATOM   6500  C CG  . ASN B 1 373 ? -22.980 50.268  17.339  1.00 40.86  ? 373 ASN B CG  1 
ATOM   6501  O OD1 . ASN B 1 373 ? -22.567 51.440  17.259  1.00 41.42  ? 373 ASN B OD1 1 
ATOM   6502  N ND2 . ASN B 1 373 ? -22.473 49.264  16.642  1.00 44.45  ? 373 ASN B ND2 1 
ATOM   6503  N N   . VAL B 1 374 ? -23.318 51.908  20.159  1.00 33.07  ? 374 VAL B N   1 
ATOM   6504  C CA  . VAL B 1 374 ? -22.708 52.890  21.044  1.00 31.25  ? 374 VAL B CA  1 
ATOM   6505  C C   . VAL B 1 374 ? -21.884 53.874  20.218  1.00 30.69  ? 374 VAL B C   1 
ATOM   6506  O O   . VAL B 1 374 ? -21.780 55.060  20.564  1.00 26.97  ? 374 VAL B O   1 
ATOM   6507  C CB  . VAL B 1 374 ? -21.878 52.212  22.152  1.00 32.61  ? 374 VAL B CB  1 
ATOM   6508  C CG1 . VAL B 1 374 ? -20.769 51.294  21.617  1.00 31.84  ? 374 VAL B CG1 1 
ATOM   6509  C CG2 . VAL B 1 374 ? -21.333 53.225  23.156  1.00 31.38  ? 374 VAL B CG2 1 
ATOM   6510  N N   . ASP B 1 375 ? -21.362 53.371  19.092  1.00 31.87  ? 375 ASP B N   1 
ATOM   6511  C CA  . ASP B 1 375 ? -20.403 54.111  18.277  1.00 34.91  ? 375 ASP B CA  1 
ATOM   6512  C C   . ASP B 1 375 ? -21.101 55.235  17.492  1.00 34.16  ? 375 ASP B C   1 
ATOM   6513  O O   . ASP B 1 375 ? -20.474 56.205  17.019  1.00 31.31  ? 375 ASP B O   1 
ATOM   6514  C CB  . ASP B 1 375 ? -19.603 53.131  17.438  1.00 34.50  ? 375 ASP B CB  1 
ATOM   6515  C CG  . ASP B 1 375 ? -18.727 52.162  18.216  1.00 34.12  ? 375 ASP B CG  1 
ATOM   6516  O OD1 . ASP B 1 375 ? -18.030 52.622  19.142  1.00 34.35  ? 375 ASP B OD1 1 
ATOM   6517  O OD2 . ASP B 1 375 ? -18.696 50.976  17.839  1.00 37.83  ? 375 ASP B OD2 1 
ATOM   6518  N N   . ALA B 1 376 ? -22.427 55.121  17.412  1.00 30.03  ? 376 ALA B N   1 
ATOM   6519  C CA  . ALA B 1 376 ? -23.201 56.118  16.719  1.00 31.32  ? 376 ALA B CA  1 
ATOM   6520  C C   . ALA B 1 376 ? -23.212 57.430  17.495  1.00 31.17  ? 376 ALA B C   1 
ATOM   6521  O O   . ALA B 1 376 ? -23.398 58.485  16.897  1.00 35.13  ? 376 ALA B O   1 
ATOM   6522  C CB  . ALA B 1 376 ? -24.585 55.576  16.472  1.00 33.21  ? 376 ALA B CB  1 
ATOM   6523  N N   . HIS B 1 377 ? -23.014 57.373  18.820  1.00 33.29  ? 377 HIS B N   1 
ATOM   6524  C CA  . HIS B 1 377 ? -23.243 58.537  19.673  1.00 30.19  ? 377 HIS B CA  1 
ATOM   6525  C C   . HIS B 1 377 ? -21.972 59.126  20.298  1.00 29.96  ? 377 HIS B C   1 
ATOM   6526  O O   . HIS B 1 377 ? -22.013 60.284  20.706  1.00 32.87  ? 377 HIS B O   1 
ATOM   6527  C CB  . HIS B 1 377 ? -24.224 58.211  20.801  1.00 27.36  ? 377 HIS B CB  1 
ATOM   6528  C CG  . HIS B 1 377 ? -25.187 59.309  21.025  1.00 27.16  ? 377 HIS B CG  1 
ATOM   6529  N ND1 . HIS B 1 377 ? -24.782 60.609  21.179  1.00 28.61  ? 377 HIS B ND1 1 
ATOM   6530  C CD2 . HIS B 1 377 ? -26.524 59.331  21.062  1.00 27.30  ? 377 HIS B CD2 1 
ATOM   6531  C CE1 . HIS B 1 377 ? -25.856 61.382  21.314  1.00 28.78  ? 377 HIS B CE1 1 
ATOM   6532  N NE2 . HIS B 1 377 ? -26.922 60.631  21.228  1.00 27.03  ? 377 HIS B NE2 1 
ATOM   6533  N N   . SER B 1 378 ? -20.868 58.359  20.406  1.00 28.03  ? 378 SER B N   1 
ATOM   6534  C CA  . SER B 1 378 ? -19.745 58.749  21.259  1.00 25.75  ? 378 SER B CA  1 
ATOM   6535  C C   . SER B 1 378 ? -18.917 59.894  20.663  1.00 27.22  ? 378 SER B C   1 
ATOM   6536  O O   . SER B 1 378 ? -18.506 60.778  21.405  1.00 31.10  ? 378 SER B O   1 
ATOM   6537  C CB  . SER B 1 378 ? -18.893 57.562  21.616  1.00 25.47  ? 378 SER B CB  1 
ATOM   6538  O OG  . SER B 1 378 ? -18.680 56.711  20.503  1.00 24.87  ? 378 SER B OG  1 
ATOM   6539  N N   . GLY B 1 379 ? -18.727 59.923  19.337  1.00 25.74  ? 379 GLY B N   1 
ATOM   6540  C CA  . GLY B 1 379 ? -17.950 60.960  18.668  1.00 25.21  ? 379 GLY B CA  1 
ATOM   6541  C C   . GLY B 1 379 ? -18.450 62.391  18.865  1.00 27.56  ? 379 GLY B C   1 
ATOM   6542  O O   . GLY B 1 379 ? -17.650 63.289  19.125  1.00 25.79  ? 379 GLY B O   1 
ATOM   6543  N N   . VAL B 1 380 ? -19.762 62.621  18.701  1.00 31.63  ? 380 VAL B N   1 
ATOM   6544  C CA  . VAL B 1 380 ? -20.336 63.955  18.838  1.00 33.03  ? 380 VAL B CA  1 
ATOM   6545  C C   . VAL B 1 380 ? -20.139 64.471  20.259  1.00 30.22  ? 380 VAL B C   1 
ATOM   6546  O O   . VAL B 1 380 ? -19.991 65.670  20.469  1.00 30.93  ? 380 VAL B O   1 
ATOM   6547  C CB  . VAL B 1 380 ? -21.820 64.062  18.435  1.00 37.90  ? 380 VAL B CB  1 
ATOM   6548  C CG1 . VAL B 1 380 ? -21.976 63.966  16.926  1.00 39.87  ? 380 VAL B CG1 1 
ATOM   6549  C CG2 . VAL B 1 380 ? -22.700 63.016  19.121  1.00 38.75  ? 380 VAL B CG2 1 
ATOM   6550  N N   . LEU B 1 381 ? -20.141 63.573  21.238  1.00 31.96  ? 381 LEU B N   1 
ATOM   6551  C CA  . LEU B 1 381 ? -19.952 63.985  22.623  1.00 32.54  ? 381 LEU B CA  1 
ATOM   6552  C C   . LEU B 1 381 ? -18.510 64.469  22.803  1.00 28.11  ? 381 LEU B C   1 
ATOM   6553  O O   . LEU B 1 381 ? -18.258 65.574  23.256  1.00 23.52  ? 381 LEU B O   1 
ATOM   6554  C CB  . LEU B 1 381 ? -20.326 62.830  23.555  1.00 32.98  ? 381 LEU B CB  1 
ATOM   6555  C CG  . LEU B 1 381 ? -21.792 62.377  23.516  1.00 36.30  ? 381 LEU B CG  1 
ATOM   6556  C CD1 . LEU B 1 381 ? -22.113 61.212  24.435  1.00 35.35  ? 381 LEU B CD1 1 
ATOM   6557  C CD2 . LEU B 1 381 ? -22.692 63.539  23.869  1.00 39.87  ? 381 LEU B CD2 1 
ATOM   6558  N N   . LEU B 1 382 ? -17.547 63.667  22.355  1.00 30.04  ? 382 LEU B N   1 
ATOM   6559  C CA  . LEU B 1 382 ? -16.150 64.068  22.447  1.00 29.50  ? 382 LEU B CA  1 
ATOM   6560  C C   . LEU B 1 382 ? -15.962 65.409  21.747  1.00 27.19  ? 382 LEU B C   1 
ATOM   6561  O O   . LEU B 1 382 ? -15.371 66.313  22.312  1.00 26.01  ? 382 LEU B O   1 
ATOM   6562  C CB  . LEU B 1 382 ? -15.253 62.973  21.882  1.00 27.35  ? 382 LEU B CB  1 
ATOM   6563  C CG  . LEU B 1 382 ? -15.311 61.670  22.687  1.00 28.79  ? 382 LEU B CG  1 
ATOM   6564  C CD1 . LEU B 1 382 ? -14.677 60.496  21.960  1.00 29.08  ? 382 LEU B CD1 1 
ATOM   6565  C CD2 . LEU B 1 382 ? -14.679 61.849  24.075  1.00 29.13  ? 382 LEU B CD2 1 
ATOM   6566  N N   . TRP B 1 383 ? -16.527 65.544  20.545  1.00 28.28  ? 383 TRP B N   1 
ATOM   6567  C CA  . TRP B 1 383 ? -16.209 66.658  19.668  1.00 27.27  ? 383 TRP B CA  1 
ATOM   6568  C C   . TRP B 1 383 ? -16.755 67.937  20.267  1.00 28.69  ? 383 TRP B C   1 
ATOM   6569  O O   . TRP B 1 383 ? -16.060 68.973  20.280  1.00 25.41  ? 383 TRP B O   1 
ATOM   6570  C CB  . TRP B 1 383 ? -16.789 66.427  18.273  1.00 28.46  ? 383 TRP B CB  1 
ATOM   6571  C CG  . TRP B 1 383 ? -16.442 67.505  17.285  1.00 28.62  ? 383 TRP B CG  1 
ATOM   6572  C CD1 . TRP B 1 383 ? -17.121 68.669  17.073  1.00 26.87  ? 383 TRP B CD1 1 
ATOM   6573  C CD2 . TRP B 1 383 ? -15.336 67.492  16.351  1.00 29.57  ? 383 TRP B CD2 1 
ATOM   6574  N NE1 . TRP B 1 383 ? -16.511 69.375  16.067  1.00 29.22  ? 383 TRP B NE1 1 
ATOM   6575  C CE2 . TRP B 1 383 ? -15.421 68.690  15.607  1.00 28.60  ? 383 TRP B CE2 1 
ATOM   6576  C CE3 . TRP B 1 383 ? -14.292 66.596  16.073  1.00 26.71  ? 383 TRP B CE3 1 
ATOM   6577  C CZ2 . TRP B 1 383 ? -14.491 69.020  14.616  1.00 29.82  ? 383 TRP B CZ2 1 
ATOM   6578  C CZ3 . TRP B 1 383 ? -13.377 66.914  15.094  1.00 26.64  ? 383 TRP B CZ3 1 
ATOM   6579  C CH2 . TRP B 1 383 ? -13.473 68.115  14.378  1.00 29.26  ? 383 TRP B CH2 1 
ATOM   6580  N N   . HIS B 1 384 ? -17.982 67.802  20.812  1.00 28.77  ? 384 HIS B N   1 
ATOM   6581  C CA  . HIS B 1 384 ? -18.676 68.924  21.426  1.00 30.52  ? 384 HIS B CA  1 
ATOM   6582  C C   . HIS B 1 384 ? -17.773 69.565  22.489  1.00 31.89  ? 384 HIS B C   1 
ATOM   6583  O O   . HIS B 1 384 ? -17.798 70.783  22.624  1.00 30.18  ? 384 HIS B O   1 
ATOM   6584  C CB  . HIS B 1 384 ? -20.073 68.545  21.969  1.00 30.48  ? 384 HIS B CB  1 
ATOM   6585  C CG  . HIS B 1 384 ? -20.642 69.630  22.826  1.00 30.31  ? 384 HIS B CG  1 
ATOM   6586  N ND1 . HIS B 1 384 ? -21.238 70.746  22.286  1.00 28.14  ? 384 HIS B ND1 1 
ATOM   6587  C CD2 . HIS B 1 384 ? -20.619 69.827  24.166  1.00 31.18  ? 384 HIS B CD2 1 
ATOM   6588  C CE1 . HIS B 1 384 ? -21.565 71.582  23.268  1.00 30.40  ? 384 HIS B CE1 1 
ATOM   6589  N NE2 . HIS B 1 384 ? -21.212 71.043  24.425  1.00 30.42  ? 384 HIS B NE2 1 
ATOM   6590  N N   . TYR B 1 385 ? -16.980 68.764  23.231  1.00 30.65  ? 385 TYR B N   1 
ATOM   6591  C CA  . TYR B 1 385 ? -16.221 69.304  24.360  1.00 34.17  ? 385 TYR B CA  1 
ATOM   6592  C C   . TYR B 1 385 ? -14.777 69.643  23.974  1.00 32.37  ? 385 TYR B C   1 
ATOM   6593  O O   . TYR B 1 385 ? -13.984 70.027  24.840  1.00 34.76  ? 385 TYR B O   1 
ATOM   6594  C CB  . TYR B 1 385 ? -16.247 68.433  25.627  1.00 31.28  ? 385 TYR B CB  1 
ATOM   6595  C CG  . TYR B 1 385 ? -17.608 68.426  26.295  1.00 26.86  ? 385 TYR B CG  1 
ATOM   6596  C CD1 . TYR B 1 385 ? -18.051 69.522  27.027  1.00 26.27  ? 385 TYR B CD1 1 
ATOM   6597  C CD2 . TYR B 1 385 ? -18.470 67.337  26.157  1.00 28.35  ? 385 TYR B CD2 1 
ATOM   6598  C CE1 . TYR B 1 385 ? -19.302 69.520  27.632  1.00 25.78  ? 385 TYR B CE1 1 
ATOM   6599  C CE2 . TYR B 1 385 ? -19.721 67.320  26.766  1.00 28.82  ? 385 TYR B CE2 1 
ATOM   6600  C CZ  . TYR B 1 385 ? -20.137 68.420  27.504  1.00 27.44  ? 385 TYR B CZ  1 
ATOM   6601  O OH  . TYR B 1 385 ? -21.374 68.425  28.087  1.00 34.31  ? 385 TYR B OH  1 
ATOM   6602  N N   . GLY B 1 386 ? -14.447 69.559  22.681  1.00 31.34  ? 386 GLY B N   1 
ATOM   6603  C CA  . GLY B 1 386 ? -13.126 69.947  22.205  1.00 28.00  ? 386 GLY B CA  1 
ATOM   6604  C C   . GLY B 1 386 ? -12.152 68.776  22.080  1.00 27.18  ? 386 GLY B C   1 
ATOM   6605  O O   . GLY B 1 386 ? -11.008 69.028  21.737  1.00 28.27  ? 386 GLY B O   1 
ATOM   6606  N N   . ILE B 1 387 ? -12.589 67.517  22.312  1.00 28.25  ? 387 ILE B N   1 
ATOM   6607  C CA  . ILE B 1 387 ? -11.750 66.356  22.043  1.00 29.01  ? 387 ILE B CA  1 
ATOM   6608  C C   . ILE B 1 387 ? -11.952 65.974  20.582  1.00 29.89  ? 387 ILE B C   1 
ATOM   6609  O O   . ILE B 1 387 ? -12.873 65.225  20.245  1.00 27.27  ? 387 ILE B O   1 
ATOM   6610  C CB  . ILE B 1 387 ? -11.983 65.163  22.998  1.00 34.09  ? 387 ILE B CB  1 
ATOM   6611  C CG1 . ILE B 1 387 ? -11.650 65.475  24.469  1.00 34.71  ? 387 ILE B CG1 1 
ATOM   6612  C CG2 . ILE B 1 387 ? -11.162 63.947  22.562  1.00 35.76  ? 387 ILE B CG2 1 
ATOM   6613  C CD1 . ILE B 1 387 ? -12.810 65.995  25.292  1.00 38.57  ? 387 ILE B CD1 1 
ATOM   6614  N N   . ARG B 1 388 ? -11.038 66.473  19.734  1.00 30.76  ? 388 ARG B N   1 
ATOM   6615  C CA  . ARG B 1 388 ? -11.213 66.457  18.290  1.00 33.78  ? 388 ARG B CA  1 
ATOM   6616  C C   . ARG B 1 388 ? -10.254 65.519  17.566  1.00 32.01  ? 388 ARG B C   1 
ATOM   6617  O O   . ARG B 1 388 ? -10.323 65.420  16.354  1.00 31.16  ? 388 ARG B O   1 
ATOM   6618  C CB  . ARG B 1 388 ? -10.944 67.861  17.749  1.00 35.62  ? 388 ARG B CB  1 
ATOM   6619  C CG  . ARG B 1 388 ? -11.874 68.821  18.452  1.00 40.81  ? 388 ARG B CG  1 
ATOM   6620  C CD  . ARG B 1 388 ? -12.260 69.998  17.591  1.00 51.68  ? 388 ARG B CD  1 
ATOM   6621  N NE  . ARG B 1 388 ? -13.544 70.384  18.183  1.00 61.10  ? 388 ARG B NE  1 
ATOM   6622  C CZ  . ARG B 1 388 ? -14.397 71.270  17.713  1.00 61.00  ? 388 ARG B CZ  1 
ATOM   6623  N NH1 . ARG B 1 388 ? -14.078 71.950  16.623  1.00 62.76  ? 388 ARG B NH1 1 
ATOM   6624  N NH2 . ARG B 1 388 ? -15.551 71.455  18.352  1.00 52.70  ? 388 ARG B NH2 1 
ATOM   6625  N N   . GLU B 1 389 ? -9.336  64.873  18.296  1.00 33.95  ? 389 GLU B N   1 
ATOM   6626  C CA  . GLU B 1 389 ? -8.228  64.159  17.682  1.00 29.74  ? 389 GLU B CA  1 
ATOM   6627  C C   . GLU B 1 389 ? -8.658  62.727  17.407  1.00 28.33  ? 389 GLU B C   1 
ATOM   6628  O O   . GLU B 1 389 ? -8.463  61.845  18.242  1.00 30.59  ? 389 GLU B O   1 
ATOM   6629  C CB  . GLU B 1 389 ? -7.024  64.229  18.619  1.00 30.60  ? 389 GLU B CB  1 
ATOM   6630  C CG  . GLU B 1 389 ? -6.415  65.627  18.696  1.00 30.55  ? 389 GLU B CG  1 
ATOM   6631  C CD  . GLU B 1 389 ? -7.111  66.610  19.628  1.00 31.50  ? 389 GLU B CD  1 
ATOM   6632  O OE1 . GLU B 1 389 ? -6.801  67.811  19.456  1.00 32.60  ? 389 GLU B OE1 1 
ATOM   6633  O OE2 . GLU B 1 389 ? -7.906  66.212  20.517  1.00 28.44  ? 389 GLU B OE2 1 
ATOM   6634  N N   . TYR B 1 390 ? -9.244  62.531  16.224  1.00 26.05  ? 390 TYR B N   1 
ATOM   6635  C CA  . TYR B 1 390 ? -9.891  61.287  15.850  1.00 26.73  ? 390 TYR B CA  1 
ATOM   6636  C C   . TYR B 1 390 ? -9.055  60.090  16.276  1.00 25.65  ? 390 TYR B C   1 
ATOM   6637  O O   . TYR B 1 390 ? -9.534  59.251  17.024  1.00 26.68  ? 390 TYR B O   1 
ATOM   6638  C CB  . TYR B 1 390 ? -10.118 61.202  14.341  1.00 29.21  ? 390 TYR B CB  1 
ATOM   6639  C CG  . TYR B 1 390 ? -11.031 62.281  13.773  1.00 30.99  ? 390 TYR B CG  1 
ATOM   6640  C CD1 . TYR B 1 390 ? -12.418 62.155  13.810  1.00 30.66  ? 390 TYR B CD1 1 
ATOM   6641  C CD2 . TYR B 1 390 ? -10.501 63.425  13.195  1.00 30.04  ? 390 TYR B CD2 1 
ATOM   6642  C CE1 . TYR B 1 390 ? -13.246 63.135  13.286  1.00 30.22  ? 390 TYR B CE1 1 
ATOM   6643  C CE2 . TYR B 1 390 ? -11.319 64.399  12.651  1.00 34.06  ? 390 TYR B CE2 1 
ATOM   6644  C CZ  . TYR B 1 390 ? -12.695 64.260  12.709  1.00 31.15  ? 390 TYR B CZ  1 
ATOM   6645  O OH  . TYR B 1 390 ? -13.464 65.251  12.202  1.00 30.50  ? 390 TYR B OH  1 
ATOM   6646  N N   . ASP B 1 391 ? -7.808  60.013  15.810  1.00 26.34  ? 391 ASP B N   1 
ATOM   6647  C CA  . ASP B 1 391 ? -6.973  58.845  16.059  1.00 27.19  ? 391 ASP B CA  1 
ATOM   6648  C C   . ASP B 1 391 ? -6.958  58.470  17.539  1.00 27.31  ? 391 ASP B C   1 
ATOM   6649  O O   . ASP B 1 391 ? -6.972  57.280  17.868  1.00 30.65  ? 391 ASP B O   1 
ATOM   6650  C CB  . ASP B 1 391 ? -5.544  59.096  15.632  1.00 28.70  ? 391 ASP B CB  1 
ATOM   6651  C CG  . ASP B 1 391 ? -5.279  59.140  14.140  1.00 27.33  ? 391 ASP B CG  1 
ATOM   6652  O OD1 . ASP B 1 391 ? -6.193  58.826  13.349  1.00 30.98  ? 391 ASP B OD1 1 
ATOM   6653  O OD2 . ASP B 1 391 ? -4.156  59.502  13.802  1.00 27.84  ? 391 ASP B OD2 1 
ATOM   6654  N N   . PHE B 1 392 ? -6.946  59.497  18.404  1.00 25.22  ? 392 PHE B N   1 
ATOM   6655  C CA  . PHE B 1 392 ? -6.893  59.319  19.848  1.00 25.15  ? 392 PHE B CA  1 
ATOM   6656  C C   . PHE B 1 392 ? -8.147  58.619  20.381  1.00 24.51  ? 392 PHE B C   1 
ATOM   6657  O O   . PHE B 1 392 ? -8.148  58.120  21.492  1.00 26.55  ? 392 PHE B O   1 
ATOM   6658  C CB  . PHE B 1 392 ? -6.704  60.647  20.594  1.00 22.42  ? 392 PHE B CB  1 
ATOM   6659  C CG  . PHE B 1 392 ? -6.220  60.443  22.024  1.00 25.12  ? 392 PHE B CG  1 
ATOM   6660  C CD1 . PHE B 1 392 ? -4.933  60.001  22.289  1.00 28.87  ? 392 PHE B CD1 1 
ATOM   6661  C CD2 . PHE B 1 392 ? -7.058  60.643  23.104  1.00 25.11  ? 392 PHE B CD2 1 
ATOM   6662  C CE1 . PHE B 1 392 ? -4.508  59.775  23.582  1.00 26.76  ? 392 PHE B CE1 1 
ATOM   6663  C CE2 . PHE B 1 392 ? -6.618  60.451  24.389  1.00 24.71  ? 392 PHE B CE2 1 
ATOM   6664  C CZ  . PHE B 1 392 ? -5.353  59.999  24.621  1.00 28.29  ? 392 PHE B CZ  1 
ATOM   6665  N N   . TYR B 1 393 ? -9.249  58.627  19.640  1.00 26.56  ? 393 TYR B N   1 
ATOM   6666  C CA  . TYR B 1 393 ? -10.497 58.070  20.149  1.00 25.35  ? 393 TYR B CA  1 
ATOM   6667  C C   . TYR B 1 393 ? -10.289 56.608  20.529  1.00 24.59  ? 393 TYR B C   1 
ATOM   6668  O O   . TYR B 1 393 ? -10.772 56.151  21.554  1.00 23.01  ? 393 TYR B O   1 
ATOM   6669  C CB  . TYR B 1 393 ? -11.601 58.271  19.109  1.00 25.64  ? 393 TYR B CB  1 
ATOM   6670  C CG  . TYR B 1 393 ? -12.100 59.703  18.966  1.00 28.09  ? 393 TYR B CG  1 
ATOM   6671  C CD1 . TYR B 1 393 ? -11.403 60.814  19.461  1.00 28.14  ? 393 TYR B CD1 1 
ATOM   6672  C CD2 . TYR B 1 393 ? -13.307 59.941  18.329  1.00 30.11  ? 393 TYR B CD2 1 
ATOM   6673  C CE1 . TYR B 1 393 ? -11.911 62.105  19.327  1.00 28.49  ? 393 TYR B CE1 1 
ATOM   6674  C CE2 . TYR B 1 393 ? -13.822 61.224  18.193  1.00 31.56  ? 393 TYR B CE2 1 
ATOM   6675  C CZ  . TYR B 1 393 ? -13.126 62.313  18.684  1.00 31.03  ? 393 TYR B CZ  1 
ATOM   6676  O OH  . TYR B 1 393 ? -13.719 63.537  18.475  1.00 32.64  ? 393 TYR B OH  1 
ATOM   6677  N N   . THR B 1 394 ? -9.480  55.879  19.763  1.00 25.75  ? 394 THR B N   1 
ATOM   6678  C CA  . THR B 1 394 ? -9.297  54.466  20.068  1.00 25.26  ? 394 THR B CA  1 
ATOM   6679  C C   . THR B 1 394 ? -8.596  54.258  21.415  1.00 25.50  ? 394 THR B C   1 
ATOM   6680  O O   . THR B 1 394 ? -8.791  53.217  22.070  1.00 25.17  ? 394 THR B O   1 
ATOM   6681  C CB  . THR B 1 394 ? -8.583  53.768  18.917  1.00 23.89  ? 394 THR B CB  1 
ATOM   6682  O OG1 . THR B 1 394 ? -9.199  54.182  17.694  1.00 23.11  ? 394 THR B OG1 1 
ATOM   6683  C CG2 . THR B 1 394 ? -8.693  52.264  19.056  1.00 22.89  ? 394 THR B CG2 1 
ATOM   6684  N N   . VAL B 1 395 ? -7.816  55.257  21.849  1.00 26.77  ? 395 VAL B N   1 
ATOM   6685  C CA  . VAL B 1 395 ? -7.081  55.172  23.108  1.00 29.35  ? 395 VAL B CA  1 
ATOM   6686  C C   . VAL B 1 395 ? -8.039  55.327  24.287  1.00 27.43  ? 395 VAL B C   1 
ATOM   6687  O O   . VAL B 1 395 ? -7.942  54.566  25.251  1.00 26.32  ? 395 VAL B O   1 
ATOM   6688  C CB  . VAL B 1 395 ? -5.902  56.161  23.232  1.00 30.69  ? 395 VAL B CB  1 
ATOM   6689  C CG1 . VAL B 1 395 ? -5.251  56.130  24.621  1.00 30.20  ? 395 VAL B CG1 1 
ATOM   6690  C CG2 . VAL B 1 395 ? -4.869  55.901  22.145  1.00 29.44  ? 395 VAL B CG2 1 
ATOM   6691  N N   . LEU B 1 396 ? -8.920  56.329  24.213  1.00 26.46  ? 396 LEU B N   1 
ATOM   6692  C CA  . LEU B 1 396 ? -9.971  56.476  25.204  1.00 27.89  ? 396 LEU B CA  1 
ATOM   6693  C C   . LEU B 1 396 ? -10.741 55.159  25.319  1.00 26.08  ? 396 LEU B C   1 
ATOM   6694  O O   . LEU B 1 396 ? -10.998 54.660  26.412  1.00 25.65  ? 396 LEU B O   1 
ATOM   6695  C CB  . LEU B 1 396 ? -10.890 57.642  24.853  1.00 29.18  ? 396 LEU B CB  1 
ATOM   6696  C CG  . LEU B 1 396 ? -10.250 59.036  24.786  1.00 27.09  ? 396 LEU B CG  1 
ATOM   6697  C CD1 . LEU B 1 396 ? -11.243 60.101  24.301  1.00 26.63  ? 396 LEU B CD1 1 
ATOM   6698  C CD2 . LEU B 1 396 ? -9.703  59.417  26.124  1.00 26.71  ? 396 LEU B CD2 1 
ATOM   6699  N N   . PHE B 1 397 ? -11.062 54.560  24.182  1.00 25.48  ? 397 PHE B N   1 
ATOM   6700  C CA  . PHE B 1 397 ? -11.755 53.284  24.197  1.00 26.51  ? 397 PHE B CA  1 
ATOM   6701  C C   . PHE B 1 397 ? -10.923 52.268  24.976  1.00 25.42  ? 397 PHE B C   1 
ATOM   6702  O O   . PHE B 1 397 ? -11.453 51.564  25.833  1.00 22.68  ? 397 PHE B O   1 
ATOM   6703  C CB  . PHE B 1 397 ? -12.054 52.919  22.741  1.00 28.18  ? 397 PHE B CB  1 
ATOM   6704  C CG  . PHE B 1 397 ? -12.911 51.685  22.514  1.00 30.82  ? 397 PHE B CG  1 
ATOM   6705  C CD1 . PHE B 1 397 ? -13.550 51.035  23.560  1.00 30.92  ? 397 PHE B CD1 1 
ATOM   6706  C CD2 . PHE B 1 397 ? -13.103 51.201  21.225  1.00 36.39  ? 397 PHE B CD2 1 
ATOM   6707  C CE1 . PHE B 1 397 ? -14.303 49.889  23.337  1.00 34.08  ? 397 PHE B CE1 1 
ATOM   6708  C CE2 . PHE B 1 397 ? -13.885 50.070  21.001  1.00 40.58  ? 397 PHE B CE2 1 
ATOM   6709  C CZ  . PHE B 1 397 ? -14.471 49.406  22.064  1.00 36.05  ? 397 PHE B CZ  1 
ATOM   6710  N N   . GLY B 1 398 ? -9.608  52.229  24.706  1.00 26.36  ? 398 GLY B N   1 
ATOM   6711  C CA  . GLY B 1 398 ? -8.716  51.244  25.318  1.00 24.12  ? 398 GLY B CA  1 
ATOM   6712  C C   . GLY B 1 398 ? -8.621  51.406  26.835  1.00 25.04  ? 398 GLY B C   1 
ATOM   6713  O O   . GLY B 1 398 ? -8.679  50.427  27.576  1.00 25.31  ? 398 GLY B O   1 
ATOM   6714  N N   . VAL B 1 399 ? -8.494  52.657  27.294  1.00 25.35  ? 399 VAL B N   1 
ATOM   6715  C CA  . VAL B 1 399 ? -8.495  52.957  28.716  1.00 25.67  ? 399 VAL B CA  1 
ATOM   6716  C C   . VAL B 1 399 ? -9.725  52.317  29.373  1.00 28.10  ? 399 VAL B C   1 
ATOM   6717  O O   . VAL B 1 399 ? -9.566  51.649  30.392  1.00 26.30  ? 399 VAL B O   1 
ATOM   6718  C CB  . VAL B 1 399 ? -8.427  54.477  28.997  1.00 25.91  ? 399 VAL B CB  1 
ATOM   6719  C CG1 . VAL B 1 399 ? -8.621  54.799  30.478  1.00 25.07  ? 399 VAL B CG1 1 
ATOM   6720  C CG2 . VAL B 1 399 ? -7.130  55.119  28.491  1.00 24.86  ? 399 VAL B CG2 1 
ATOM   6721  N N   . SER B 1 400 ? -10.927 52.548  28.803  1.00 28.41  ? 400 SER B N   1 
ATOM   6722  C CA  . SER B 1 400 ? -12.185 52.045  29.349  1.00 28.81  ? 400 SER B CA  1 
ATOM   6723  C C   . SER B 1 400 ? -12.170 50.519  29.410  1.00 28.67  ? 400 SER B C   1 
ATOM   6724  O O   . SER B 1 400 ? -12.448 49.901  30.452  1.00 29.03  ? 400 SER B O   1 
ATOM   6725  C CB  . SER B 1 400 ? -13.387 52.523  28.525  1.00 29.56  ? 400 SER B CB  1 
ATOM   6726  O OG  . SER B 1 400 ? -14.637 51.933  28.902  1.00 26.40  ? 400 SER B OG  1 
ATOM   6727  N N   . ARG B 1 401 ? -11.849 49.923  28.267  1.00 27.46  ? 401 ARG B N   1 
ATOM   6728  C CA  . ARG B 1 401 ? -11.960 48.487  28.081  1.00 28.59  ? 401 ARG B CA  1 
ATOM   6729  C C   . ARG B 1 401 ? -10.936 47.734  28.935  1.00 28.57  ? 401 ARG B C   1 
ATOM   6730  O O   . ARG B 1 401 ? -11.081 46.539  29.193  1.00 28.19  ? 401 ARG B O   1 
ATOM   6731  C CB  . ARG B 1 401 ? -11.884 48.255  26.566  1.00 30.84  ? 401 ARG B CB  1 
ATOM   6732  C CG  . ARG B 1 401 ? -12.222 46.860  26.066  1.00 33.39  ? 401 ARG B CG  1 
ATOM   6733  C CD  . ARG B 1 401 ? -13.529 46.290  26.558  1.00 33.79  ? 401 ARG B CD  1 
ATOM   6734  N NE  . ARG B 1 401 ? -14.740 46.984  26.115  1.00 35.85  ? 401 ARG B NE  1 
ATOM   6735  C CZ  . ARG B 1 401 ? -15.355 46.688  24.984  1.00 39.73  ? 401 ARG B CZ  1 
ATOM   6736  N NH1 . ARG B 1 401 ? -14.819 45.827  24.130  1.00 43.18  ? 401 ARG B NH1 1 
ATOM   6737  N NH2 . ARG B 1 401 ? -16.490 47.276  24.702  1.00 40.17  ? 401 ARG B NH2 1 
ATOM   6738  N N   . ALA B 1 402 ? -9.914  48.436  29.441  1.00 31.42  ? 402 ALA B N   1 
ATOM   6739  C CA  . ALA B 1 402 ? -9.054  47.879  30.484  1.00 30.94  ? 402 ALA B CA  1 
ATOM   6740  C C   . ALA B 1 402 ? -9.840  47.375  31.699  1.00 28.34  ? 402 ALA B C   1 
ATOM   6741  O O   . ALA B 1 402 ? -9.451  46.390  32.325  1.00 23.92  ? 402 ALA B O   1 
ATOM   6742  C CB  . ALA B 1 402 ? -8.052  48.915  30.908  1.00 35.06  ? 402 ALA B CB  1 
ATOM   6743  N N   . LEU B 1 403 ? -10.915 48.079  32.073  1.00 27.97  ? 403 LEU B N   1 
ATOM   6744  C CA  . LEU B 1 403 ? -11.672 47.715  33.264  1.00 27.74  ? 403 LEU B CA  1 
ATOM   6745  C C   . LEU B 1 403 ? -12.211 46.292  33.122  1.00 26.75  ? 403 LEU B C   1 
ATOM   6746  O O   . LEU B 1 403 ? -12.064 45.445  33.999  1.00 29.61  ? 403 LEU B O   1 
ATOM   6747  C CB  . LEU B 1 403 ? -12.797 48.723  33.470  1.00 27.25  ? 403 LEU B CB  1 
ATOM   6748  C CG  . LEU B 1 403 ? -12.359 50.172  33.686  1.00 27.89  ? 403 LEU B CG  1 
ATOM   6749  C CD1 . LEU B 1 403 ? -13.528 51.097  33.366  1.00 30.28  ? 403 LEU B CD1 1 
ATOM   6750  C CD2 . LEU B 1 403 ? -11.827 50.437  35.086  1.00 27.01  ? 403 LEU B CD2 1 
ATOM   6751  N N   . GLY B 1 404 ? -12.802 46.011  31.977  1.00 29.07  ? 404 GLY B N   1 
ATOM   6752  C CA  . GLY B 1 404 ? -13.322 44.686  31.717  1.00 30.01  ? 404 GLY B CA  1 
ATOM   6753  C C   . GLY B 1 404 ? -12.210 43.675  31.478  1.00 28.70  ? 404 GLY B C   1 
ATOM   6754  O O   . GLY B 1 404 ? -12.338 42.559  31.936  1.00 29.39  ? 404 GLY B O   1 
ATOM   6755  N N   . CYS B 1 405 ? -11.167 44.066  30.725  1.00 30.65  ? 405 CYS B N   1 
ATOM   6756  C CA  . CYS B 1 405 ? -10.034 43.199  30.403  1.00 28.30  ? 405 CYS B CA  1 
ATOM   6757  C C   . CYS B 1 405 ? -9.355  42.717  31.691  1.00 25.15  ? 405 CYS B C   1 
ATOM   6758  O O   . CYS B 1 405 ? -9.080  41.537  31.821  1.00 23.96  ? 405 CYS B O   1 
ATOM   6759  C CB  . CYS B 1 405 ? -9.103  43.849  29.368  1.00 28.72  ? 405 CYS B CB  1 
ATOM   6760  S SG  . CYS B 1 405 ? -9.669  43.709  27.636  1.00 29.57  ? 405 CYS B SG  1 
ATOM   6761  N N   . THR B 1 406 ? -9.148  43.613  32.666  1.00 24.35  ? 406 THR B N   1 
ATOM   6762  C CA  . THR B 1 406 ? -8.515  43.263  33.924  1.00 23.11  ? 406 THR B CA  1 
ATOM   6763  C C   . THR B 1 406 ? -9.421  42.341  34.727  1.00 25.44  ? 406 THR B C   1 
ATOM   6764  O O   . THR B 1 406 ? -8.990  41.291  35.205  1.00 30.82  ? 406 THR B O   1 
ATOM   6765  C CB  . THR B 1 406 ? -8.143  44.514  34.718  1.00 21.89  ? 406 THR B CB  1 
ATOM   6766  O OG1 . THR B 1 406 ? -9.282  45.345  34.959  1.00 20.66  ? 406 THR B OG1 1 
ATOM   6767  C CG2 . THR B 1 406 ? -7.008  45.259  34.033  1.00 21.45  ? 406 THR B CG2 1 
ATOM   6768  N N   . ALA B 1 407 ? -10.683 42.733  34.865  1.00 25.26  ? 407 ALA B N   1 
ATOM   6769  C CA  . ALA B 1 407 ? -11.626 41.933  35.623  1.00 25.71  ? 407 ALA B CA  1 
ATOM   6770  C C   . ALA B 1 407 ? -11.687 40.515  35.083  1.00 24.71  ? 407 ALA B C   1 
ATOM   6771  O O   . ALA B 1 407 ? -11.696 39.561  35.837  1.00 26.13  ? 407 ALA B O   1 
ATOM   6772  C CB  . ALA B 1 407 ? -12.964 42.592  35.571  1.00 26.72  ? 407 ALA B CB  1 
ATOM   6773  N N   . GLN B 1 408 ? -11.765 40.380  33.767  1.00 27.12  ? 408 GLN B N   1 
ATOM   6774  C CA  . GLN B 1 408 ? -11.896 39.071  33.144  1.00 29.72  ? 408 GLN B CA  1 
ATOM   6775  C C   . GLN B 1 408 ? -10.633 38.256  33.387  1.00 31.55  ? 408 GLN B C   1 
ATOM   6776  O O   . GLN B 1 408 ? -10.714 37.044  33.572  1.00 39.76  ? 408 GLN B O   1 
ATOM   6777  C CB  . GLN B 1 408 ? -12.144 39.148  31.637  1.00 30.44  ? 408 GLN B CB  1 
ATOM   6778  C CG  . GLN B 1 408 ? -13.520 39.686  31.256  1.00 31.96  ? 408 GLN B CG  1 
ATOM   6779  C CD  . GLN B 1 408 ? -13.818 39.554  29.780  1.00 31.02  ? 408 GLN B CD  1 
ATOM   6780  O OE1 . GLN B 1 408 ? -14.401 40.445  29.151  1.00 31.00  ? 408 GLN B OE1 1 
ATOM   6781  N NE2 . GLN B 1 408 ? -13.429 38.419  29.228  1.00 29.16  ? 408 GLN B NE2 1 
ATOM   6782  N N   . ALA B 1 409 ? -9.484  38.941  33.381  1.00 29.44  ? 409 ALA B N   1 
ATOM   6783  C CA  . ALA B 1 409 ? -8.187  38.298  33.447  1.00 28.86  ? 409 ALA B CA  1 
ATOM   6784  C C   . ALA B 1 409 ? -7.980  37.737  34.853  1.00 30.89  ? 409 ALA B C   1 
ATOM   6785  O O   . ALA B 1 409 ? -7.540  36.594  35.038  1.00 32.25  ? 409 ALA B O   1 
ATOM   6786  C CB  . ALA B 1 409 ? -7.098  39.284  33.039  1.00 28.05  ? 409 ALA B CB  1 
ATOM   6787  N N   . ILE B 1 410 ? -8.368  38.543  35.837  1.00 29.16  ? 410 ILE B N   1 
ATOM   6788  C CA  . ILE B 1 410 ? -8.346  38.126  37.229  1.00 30.36  ? 410 ILE B CA  1 
ATOM   6789  C C   . ILE B 1 410 ? -9.205  36.877  37.394  1.00 31.68  ? 410 ILE B C   1 
ATOM   6790  O O   . ILE B 1 410 ? -8.813  35.904  38.033  1.00 28.72  ? 410 ILE B O   1 
ATOM   6791  C CB  . ILE B 1 410 ? -8.812  39.284  38.131  1.00 29.77  ? 410 ILE B CB  1 
ATOM   6792  C CG1 . ILE B 1 410 ? -7.861  40.486  38.002  1.00 30.15  ? 410 ILE B CG1 1 
ATOM   6793  C CG2 . ILE B 1 410 ? -8.939  38.814  39.582  1.00 29.69  ? 410 ILE B CG2 1 
ATOM   6794  C CD1 . ILE B 1 410 ? -8.411  41.791  38.541  1.00 32.34  ? 410 ILE B CD1 1 
ATOM   6795  N N   . LEU B 1 411 ? -10.386 36.909  36.784  1.00 36.10  ? 411 LEU B N   1 
ATOM   6796  C CA  . LEU B 1 411 ? -11.420 35.966  37.150  1.00 36.00  ? 411 LEU B CA  1 
ATOM   6797  C C   . LEU B 1 411 ? -11.026 34.604  36.617  1.00 33.37  ? 411 LEU B C   1 
ATOM   6798  O O   . LEU B 1 411 ? -11.225 33.604  37.304  1.00 33.83  ? 411 LEU B O   1 
ATOM   6799  C CB  . LEU B 1 411 ? -12.793 36.403  36.638  1.00 36.31  ? 411 LEU B CB  1 
ATOM   6800  C CG  . LEU B 1 411 ? -13.447 37.536  37.430  1.00 37.89  ? 411 LEU B CG  1 
ATOM   6801  C CD1 . LEU B 1 411 ? -14.588 38.121  36.634  1.00 36.87  ? 411 LEU B CD1 1 
ATOM   6802  C CD2 . LEU B 1 411 ? -13.912 37.077  38.814  1.00 37.11  ? 411 LEU B CD2 1 
ATOM   6803  N N   . VAL B 1 412 ? -10.502 34.576  35.390  1.00 30.70  ? 412 VAL B N   1 
ATOM   6804  C CA  . VAL B 1 412 ? -10.264 33.287  34.763  1.00 31.17  ? 412 VAL B CA  1 
ATOM   6805  C C   . VAL B 1 412 ? -9.031  32.645  35.391  1.00 32.06  ? 412 VAL B C   1 
ATOM   6806  O O   . VAL B 1 412 ? -8.895  31.431  35.326  1.00 35.62  ? 412 VAL B O   1 
ATOM   6807  C CB  . VAL B 1 412 ? -10.159 33.364  33.229  1.00 33.86  ? 412 VAL B CB  1 
ATOM   6808  C CG1 . VAL B 1 412 ? -11.439 33.951  32.641  1.00 36.81  ? 412 VAL B CG1 1 
ATOM   6809  C CG2 . VAL B 1 412 ? -8.952  34.156  32.752  1.00 32.45  ? 412 VAL B CG2 1 
ATOM   6810  N N   . ARG B 1 413 ? -8.130  33.447  35.987  1.00 31.90  ? 413 ARG B N   1 
ATOM   6811  C CA  . ARG B 1 413 ? -7.001  32.891  36.718  1.00 32.20  ? 413 ARG B CA  1 
ATOM   6812  C C   . ARG B 1 413 ? -7.499  32.421  38.084  1.00 31.88  ? 413 ARG B C   1 
ATOM   6813  O O   . ARG B 1 413 ? -6.969  31.478  38.661  1.00 34.74  ? 413 ARG B O   1 
ATOM   6814  C CB  . ARG B 1 413 ? -5.823  33.873  36.784  1.00 32.62  ? 413 ARG B CB  1 
ATOM   6815  C CG  . ARG B 1 413 ? -5.296  34.299  35.410  1.00 34.85  ? 413 ARG B CG  1 
ATOM   6816  C CD  . ARG B 1 413 ? -4.149  33.494  34.827  1.00 31.71  ? 413 ARG B CD  1 
ATOM   6817  N NE  . ARG B 1 413 ? -4.430  32.062  34.890  1.00 34.68  ? 413 ARG B NE  1 
ATOM   6818  C CZ  . ARG B 1 413 ? -5.165  31.338  34.055  1.00 37.00  ? 413 ARG B CZ  1 
ATOM   6819  N NH1 . ARG B 1 413 ? -5.519  31.823  32.881  1.00 38.68  ? 413 ARG B NH1 1 
ATOM   6820  N NH2 . ARG B 1 413 ? -5.495  30.095  34.382  1.00 37.38  ? 413 ARG B NH2 1 
ATOM   6821  N N   . GLY B 1 414 ? -8.531  33.081  38.603  1.00 30.76  ? 414 GLY B N   1 
ATOM   6822  C CA  . GLY B 1 414 ? -9.271  32.534  39.722  1.00 29.14  ? 414 GLY B CA  1 
ATOM   6823  C C   . GLY B 1 414 ? -9.820  31.150  39.381  1.00 29.21  ? 414 GLY B C   1 
ATOM   6824  O O   . GLY B 1 414 ? -9.729  30.224  40.180  1.00 32.69  ? 414 GLY B O   1 
ATOM   6825  N N   . TYR B 1 415 ? -10.380 31.018  38.176  1.00 31.02  ? 415 TYR B N   1 
ATOM   6826  C CA  . TYR B 1 415 ? -11.067 29.805  37.752  1.00 30.48  ? 415 TYR B CA  1 
ATOM   6827  C C   . TYR B 1 415 ? -10.046 28.733  37.399  1.00 30.37  ? 415 TYR B C   1 
ATOM   6828  O O   . TYR B 1 415 ? -10.386 27.559  37.396  1.00 29.23  ? 415 TYR B O   1 
ATOM   6829  C CB  . TYR B 1 415 ? -11.961 29.966  36.509  1.00 31.80  ? 415 TYR B CB  1 
ATOM   6830  C CG  . TYR B 1 415 ? -13.129 30.946  36.592  1.00 31.99  ? 415 TYR B CG  1 
ATOM   6831  C CD1 . TYR B 1 415 ? -13.451 31.616  37.761  1.00 31.40  ? 415 TYR B CD1 1 
ATOM   6832  C CD2 . TYR B 1 415 ? -13.929 31.191  35.488  1.00 32.58  ? 415 TYR B CD2 1 
ATOM   6833  C CE1 . TYR B 1 415 ? -14.510 32.510  37.811  1.00 33.60  ? 415 TYR B CE1 1 
ATOM   6834  C CE2 . TYR B 1 415 ? -14.999 32.076  35.533  1.00 32.25  ? 415 TYR B CE2 1 
ATOM   6835  C CZ  . TYR B 1 415 ? -15.306 32.729  36.704  1.00 31.18  ? 415 TYR B CZ  1 
ATOM   6836  O OH  . TYR B 1 415 ? -16.369 33.583  36.786  1.00 30.51  ? 415 TYR B OH  1 
ATOM   6837  N N   . MET B 1 416 ? -8.840  29.174  37.025  1.00 31.90  ? 416 MET B N   1 
ATOM   6838  C CA  . MET B 1 416 ? -7.770  28.321  36.547  1.00 32.42  ? 416 MET B CA  1 
ATOM   6839  C C   . MET B 1 416 ? -8.111  27.684  35.198  1.00 32.60  ? 416 MET B C   1 
ATOM   6840  O O   . MET B 1 416 ? -7.763  26.520  34.946  1.00 31.21  ? 416 MET B O   1 
ATOM   6841  C CB  . MET B 1 416 ? -7.439  27.248  37.582  1.00 37.15  ? 416 MET B CB  1 
ATOM   6842  C CG  . MET B 1 416 ? -6.962  27.801  38.904  1.00 39.96  ? 416 MET B CG  1 
ATOM   6843  S SD  . MET B 1 416 ? -6.516  26.431  39.986  1.00 41.86  ? 416 MET B SD  1 
ATOM   6844  C CE  . MET B 1 416 ? -6.180  27.473  41.410  1.00 46.50  ? 416 MET B CE  1 
ATOM   6845  N N   . LEU B 1 417 ? -8.737  28.452  34.289  1.00 31.91  ? 417 LEU B N   1 
ATOM   6846  C CA  . LEU B 1 417 ? -9.002  27.915  32.955  1.00 31.97  ? 417 LEU B CA  1 
ATOM   6847  C C   . LEU B 1 417 ? -7.674  27.546  32.290  1.00 30.79  ? 417 LEU B C   1 
ATOM   6848  O O   . LEU B 1 417 ? -6.653  28.220  32.474  1.00 29.75  ? 417 LEU B O   1 
ATOM   6849  C CB  . LEU B 1 417 ? -9.814  28.859  32.069  1.00 31.71  ? 417 LEU B CB  1 
ATOM   6850  C CG  . LEU B 1 417 ? -11.175 29.312  32.616  1.00 36.67  ? 417 LEU B CG  1 
ATOM   6851  C CD1 . LEU B 1 417 ? -11.925 30.145  31.570  1.00 39.61  ? 417 LEU B CD1 1 
ATOM   6852  C CD2 . LEU B 1 417 ? -12.018 28.136  33.059  1.00 37.93  ? 417 LEU B CD2 1 
ATOM   6853  N N   . PRO B 1 418 ? -7.650  26.485  31.462  1.00 29.44  ? 418 PRO B N   1 
ATOM   6854  C CA  . PRO B 1 418 ? -6.421  26.029  30.828  1.00 32.97  ? 418 PRO B CA  1 
ATOM   6855  C C   . PRO B 1 418 ? -6.004  26.942  29.679  1.00 35.21  ? 418 PRO B C   1 
ATOM   6856  O O   . PRO B 1 418 ? -6.714  27.888  29.361  1.00 32.95  ? 418 PRO B O   1 
ATOM   6857  C CB  . PRO B 1 418 ? -6.857  24.630  30.343  1.00 31.70  ? 418 PRO B CB  1 
ATOM   6858  C CG  . PRO B 1 418 ? -8.283  24.825  29.904  1.00 29.74  ? 418 PRO B CG  1 
ATOM   6859  C CD  . PRO B 1 418 ? -8.815  25.720  31.001  1.00 32.22  ? 418 PRO B CD  1 
ATOM   6860  N N   . ILE B 1 419 ? -4.873  26.613  29.034  1.00 40.45  ? 419 ILE B N   1 
ATOM   6861  C CA  . ILE B 1 419 ? -4.354  27.388  27.914  1.00 40.61  ? 419 ILE B CA  1 
ATOM   6862  C C   . ILE B 1 419 ? -5.335  27.334  26.741  1.00 38.27  ? 419 ILE B C   1 
ATOM   6863  O O   . ILE B 1 419 ? -6.024  26.337  26.580  1.00 41.55  ? 419 ILE B O   1 
ATOM   6864  C CB  . ILE B 1 419 ? -2.957  26.867  27.545  1.00 39.53  ? 419 ILE B CB  1 
ATOM   6865  C CG1 . ILE B 1 419 ? -2.196  27.868  26.657  1.00 41.04  ? 419 ILE B CG1 1 
ATOM   6866  C CG2 . ILE B 1 419 ? -3.053  25.473  26.925  1.00 38.38  ? 419 ILE B CG2 1 
ATOM   6867  C CD1 . ILE B 1 419 ? -0.740  27.496  26.406  1.00 38.45  ? 419 ILE B CD1 1 
ATOM   6868  N N   . GLU B 1 420 ? -5.396  28.405  25.935  1.00 37.11  ? 420 GLU B N   1 
ATOM   6869  C CA  . GLU B 1 420 ? -6.216  28.449  24.722  1.00 35.31  ? 420 GLU B CA  1 
ATOM   6870  C C   . GLU B 1 420 ? -5.420  27.918  23.529  1.00 32.30  ? 420 GLU B C   1 
ATOM   6871  O O   . GLU B 1 420 ? -4.514  28.596  23.034  1.00 34.35  ? 420 GLU B O   1 
ATOM   6872  C CB  . GLU B 1 420 ? -6.747  29.871  24.480  1.00 34.42  ? 420 GLU B CB  1 
ATOM   6873  C CG  . GLU B 1 420 ? -7.849  30.020  23.428  1.00 32.68  ? 420 GLU B CG  1 
ATOM   6874  C CD  . GLU B 1 420 ? -8.390  31.436  23.181  1.00 31.20  ? 420 GLU B CD  1 
ATOM   6875  O OE1 . GLU B 1 420 ? -8.668  31.753  22.005  1.00 27.46  ? 420 GLU B OE1 1 
ATOM   6876  O OE2 . GLU B 1 420 ? -8.505  32.246  24.129  1.00 31.64  ? 420 GLU B OE2 1 
ATOM   6877  N N   . ARG B 1 421 ? -5.837  26.735  23.038  1.00 34.90  ? 421 ARG B N   1 
ATOM   6878  C CA  . ARG B 1 421 ? -5.186  26.007  21.947  1.00 35.40  ? 421 ARG B CA  1 
ATOM   6879  C C   . ARG B 1 421 ? -6.238  25.245  21.135  1.00 35.55  ? 421 ARG B C   1 
ATOM   6880  O O   . ARG B 1 421 ? -6.338  24.017  21.204  1.00 36.13  ? 421 ARG B O   1 
ATOM   6881  C CB  . ARG B 1 421 ? -4.088  25.046  22.422  1.00 38.29  ? 421 ARG B CB  1 
ATOM   6882  C CG  . ARG B 1 421 ? -2.911  24.762  21.494  1.00 48.47  ? 421 ARG B CG  1 
ATOM   6883  C CD  . ARG B 1 421 ? -3.042  23.577  20.498  1.00 57.09  ? 421 ARG B CD  1 
ATOM   6884  N NE  . ARG B 1 421 ? -1.860  23.349  19.639  1.00 67.64  ? 421 ARG B NE  1 
ATOM   6885  C CZ  . ARG B 1 421 ? -1.771  23.421  18.286  1.00 69.22  ? 421 ARG B CZ  1 
ATOM   6886  N NH1 . ARG B 1 421 ? -0.587  23.305  17.697  1.00 61.94  ? 421 ARG B NH1 1 
ATOM   6887  N NH2 . ARG B 1 421 ? -2.839  23.640  17.519  1.00 65.75  ? 421 ARG B NH2 1 
ATOM   6888  N N   . PRO B 1 422 ? -7.023  25.940  20.283  1.00 36.27  ? 422 PRO B N   1 
ATOM   6889  C CA  . PRO B 1 422 ? -7.893  25.271  19.317  1.00 38.95  ? 422 PRO B CA  1 
ATOM   6890  C C   . PRO B 1 422 ? -7.035  24.531  18.299  1.00 39.67  ? 422 PRO B C   1 
ATOM   6891  O O   . PRO B 1 422 ? -5.814  24.636  18.327  1.00 43.40  ? 422 PRO B O   1 
ATOM   6892  C CB  . PRO B 1 422 ? -8.671  26.420  18.659  1.00 37.39  ? 422 PRO B CB  1 
ATOM   6893  C CG  . PRO B 1 422 ? -7.712  27.586  18.752  1.00 37.65  ? 422 PRO B CG  1 
ATOM   6894  C CD  . PRO B 1 422 ? -7.053  27.403  20.125  1.00 38.33  ? 422 PRO B CD  1 
ATOM   6895  N N   . LYS B 1 423 ? -7.699  23.839  17.376  1.00 39.13  ? 423 LYS B N   1 
ATOM   6896  C CA  . LYS B 1 423 ? -7.048  23.019  16.371  1.00 42.44  ? 423 LYS B CA  1 
ATOM   6897  C C   . LYS B 1 423 ? -7.331  23.652  15.015  1.00 40.46  ? 423 LYS B C   1 
ATOM   6898  O O   . LYS B 1 423 ? -8.472  24.021  14.722  1.00 38.80  ? 423 LYS B O   1 
ATOM   6899  C CB  . LYS B 1 423 ? -7.576  21.584  16.528  1.00 44.25  ? 423 LYS B CB  1 
ATOM   6900  C CG  . LYS B 1 423 ? -7.344  20.606  15.385  1.00 47.68  ? 423 LYS B CG  1 
ATOM   6901  C CD  . LYS B 1 423 ? -5.902  20.123  15.247  1.00 54.21  ? 423 LYS B CD  1 
ATOM   6902  C CE  . LYS B 1 423 ? -5.762  19.055  14.207  1.00 59.16  ? 423 LYS B CE  1 
ATOM   6903  N NZ  . LYS B 1 423 ? -4.402  18.962  13.678  1.00 58.81  ? 423 LYS B NZ  1 
ATOM   6904  N N   . SER B 1 424 ? -6.280  23.769  14.207  1.00 39.82  ? 424 SER B N   1 
ATOM   6905  C CA  . SER B 1 424 ? -6.408  24.319  12.863  1.00 43.62  ? 424 SER B CA  1 
ATOM   6906  C C   . SER B 1 424 ? -6.685  23.189  11.869  1.00 37.57  ? 424 SER B C   1 
ATOM   6907  O O   . SER B 1 424 ? -6.353  22.046  12.151  1.00 36.05  ? 424 SER B O   1 
ATOM   6908  C CB  . SER B 1 424 ? -5.161  25.138  12.477  1.00 44.57  ? 424 SER B CB  1 
ATOM   6909  O OG  . SER B 1 424 ? -4.006  24.329  12.250  1.00 40.15  ? 424 SER B OG  1 
ATOM   6910  N N   . ILE B 1 425 ? -7.282  23.522  10.713  1.00 37.60  ? 425 ILE B N   1 
ATOM   6911  C CA  . ILE B 1 425 ? -7.520  22.575  9.625   1.00 38.24  ? 425 ILE B CA  1 
ATOM   6912  C C   . ILE B 1 425 ? -6.890  23.124  8.352   1.00 37.82  ? 425 ILE B C   1 
ATOM   6913  O O   . ILE B 1 425 ? -6.688  24.326  8.224   1.00 37.74  ? 425 ILE B O   1 
ATOM   6914  C CB  . ILE B 1 425 ? -9.024  22.320  9.401   1.00 45.54  ? 425 ILE B CB  1 
ATOM   6915  C CG1 . ILE B 1 425 ? -9.805  23.627  9.079   1.00 43.86  ? 425 ILE B CG1 1 
ATOM   6916  C CG2 . ILE B 1 425 ? -9.631  21.567  10.590  1.00 49.11  ? 425 ILE B CG2 1 
ATOM   6917  C CD1 . ILE B 1 425 ? -11.273 23.419  8.726   1.00 43.86  ? 425 ILE B CD1 1 
ATOM   6918  N N   . THR B 1 426 ? -6.597  22.222  7.413   1.00 41.69  ? 426 THR B N   1 
ATOM   6919  C CA  . THR B 1 426 ? -5.995  22.574  6.136   1.00 38.60  ? 426 THR B CA  1 
ATOM   6920  C C   . THR B 1 426 ? -7.091  22.601  5.082   1.00 36.40  ? 426 THR B C   1 
ATOM   6921  O O   . THR B 1 426 ? -8.073  21.880  5.165   1.00 39.29  ? 426 THR B O   1 
ATOM   6922  C CB  . THR B 1 426 ? -4.869  21.590  5.794   1.00 40.03  ? 426 THR B CB  1 
ATOM   6923  O OG1 . THR B 1 426 ? -5.367  20.296  5.439   1.00 38.27  ? 426 THR B OG1 1 
ATOM   6924  C CG2 . THR B 1 426 ? -3.895  21.440  6.952   1.00 37.72  ? 426 THR B CG2 1 
ATOM   6925  N N   . THR B 1 427 ? -6.925  23.465  4.092   1.00 37.82  ? 427 THR B N   1 
ATOM   6926  C CA  . THR B 1 427 ? -7.821  23.506  2.952   1.00 36.34  ? 427 THR B CA  1 
ATOM   6927  C C   . THR B 1 427 ? -7.747  22.187  2.184   1.00 35.39  ? 427 THR B C   1 
ATOM   6928  O O   . THR B 1 427 ? -8.730  21.763  1.616   1.00 41.09  ? 427 THR B O   1 
ATOM   6929  C CB  . THR B 1 427 ? -7.414  24.702  2.089   1.00 34.72  ? 427 THR B CB  1 
ATOM   6930  O OG1 . THR B 1 427 ? -7.613  25.804  2.975   1.00 31.12  ? 427 THR B OG1 1 
ATOM   6931  C CG2 . THR B 1 427 ? -8.206  24.822  0.797   1.00 31.65  ? 427 THR B CG2 1 
ATOM   6932  N N   . ARG B 1 428 ? -6.585  21.546  2.137   1.00 38.57  ? 428 ARG B N   1 
ATOM   6933  C CA  . ARG B 1 428 ? -6.442  20.294  1.416   1.00 48.04  ? 428 ARG B CA  1 
ATOM   6934  C C   . ARG B 1 428 ? -7.376  19.261  2.051   1.00 47.75  ? 428 ARG B C   1 
ATOM   6935  O O   . ARG B 1 428 ? -8.131  18.585  1.330   1.00 43.06  ? 428 ARG B O   1 
ATOM   6936  C CB  . ARG B 1 428 ? -4.963  19.873  1.377   1.00 61.10  ? 428 ARG B CB  1 
ATOM   6937  C CG  . ARG B 1 428 ? -4.663  18.423  1.016   1.00 72.17  ? 428 ARG B CG  1 
ATOM   6938  C CD  . ARG B 1 428 ? -3.830  17.725  2.109   1.00 89.87  ? 428 ARG B CD  1 
ATOM   6939  N NE  . ARG B 1 428 ? -4.287  16.362  2.429   1.00 102.19 ? 428 ARG B NE  1 
ATOM   6940  C CZ  . ARG B 1 428 ? -4.064  15.246  1.725   1.00 107.49 ? 428 ARG B CZ  1 
ATOM   6941  N NH1 . ARG B 1 428 ? -3.257  15.239  0.671   1.00 104.53 ? 428 ARG B NH1 1 
ATOM   6942  N NH2 . ARG B 1 428 ? -4.636  14.117  2.102   1.00 107.17 ? 428 ARG B NH2 1 
ATOM   6943  N N   . TRP B 1 429 ? -7.312  19.154  3.390   1.00 39.64  ? 429 TRP B N   1 
ATOM   6944  C CA  . TRP B 1 429 ? -8.104  18.186  4.130   1.00 38.99  ? 429 TRP B CA  1 
ATOM   6945  C C   . TRP B 1 429 ? -9.583  18.388  3.849   1.00 43.70  ? 429 TRP B C   1 
ATOM   6946  O O   . TRP B 1 429 ? -10.287 17.421  3.591   1.00 48.06  ? 429 TRP B O   1 
ATOM   6947  C CB  . TRP B 1 429 ? -7.873  18.322  5.632   1.00 40.08  ? 429 TRP B CB  1 
ATOM   6948  C CG  . TRP B 1 429 ? -8.792  17.467  6.465   1.00 40.09  ? 429 TRP B CG  1 
ATOM   6949  C CD1 . TRP B 1 429 ? -8.631  16.138  6.704   1.00 41.08  ? 429 TRP B CD1 1 
ATOM   6950  C CD2 . TRP B 1 429 ? -9.974  17.868  7.199   1.00 44.70  ? 429 TRP B CD2 1 
ATOM   6951  N NE1 . TRP B 1 429 ? -9.628  15.679  7.526   1.00 45.90  ? 429 TRP B NE1 1 
ATOM   6952  C CE2 . TRP B 1 429 ? -10.465 16.710  7.852   1.00 43.33  ? 429 TRP B CE2 1 
ATOM   6953  C CE3 . TRP B 1 429 ? -10.670 19.076  7.369   1.00 47.05  ? 429 TRP B CE3 1 
ATOM   6954  C CZ2 . TRP B 1 429 ? -11.602 16.721  8.657   1.00 40.34  ? 429 TRP B CZ2 1 
ATOM   6955  C CZ3 . TRP B 1 429 ? -11.802 19.088  8.161   1.00 47.31  ? 429 TRP B CZ3 1 
ATOM   6956  C CH2 . TRP B 1 429 ? -12.253 17.925  8.804   1.00 46.28  ? 429 TRP B CH2 1 
ATOM   6957  N N   . VAL B 1 430 ? -10.016 19.653  3.951   1.00 46.47  ? 430 VAL B N   1 
ATOM   6958  C CA  . VAL B 1 430 ? -11.379 20.085  3.694   1.00 50.30  ? 430 VAL B CA  1 
ATOM   6959  C C   . VAL B 1 430 ? -11.825 19.553  2.331   1.00 56.80  ? 430 VAL B C   1 
ATOM   6960  O O   . VAL B 1 430 ? -12.863 18.888  2.269   1.00 52.86  ? 430 VAL B O   1 
ATOM   6961  C CB  . VAL B 1 430 ? -11.505 21.626  3.788   1.00 54.20  ? 430 VAL B CB  1 
ATOM   6962  C CG1 . VAL B 1 430 ? -12.814 22.170  3.198   1.00 56.72  ? 430 VAL B CG1 1 
ATOM   6963  C CG2 . VAL B 1 430 ? -11.331 22.123  5.220   1.00 53.99  ? 430 VAL B CG2 1 
ATOM   6964  N N   . LYS B 1 431 ? -11.020 19.826  1.278   1.00 55.76  ? 431 LYS B N   1 
ATOM   6965  C CA  . LYS B 1 431 ? -11.395 19.585  -0.111  1.00 56.72  ? 431 LYS B CA  1 
ATOM   6966  C C   . LYS B 1 431 ? -11.588 18.094  -0.364  1.00 52.90  ? 431 LYS B C   1 
ATOM   6967  O O   . LYS B 1 431 ? -12.373 17.737  -1.236  1.00 45.15  ? 431 LYS B O   1 
ATOM   6968  C CB  . LYS B 1 431 ? -10.376 20.135  -1.120  1.00 64.76  ? 431 LYS B CB  1 
ATOM   6969  C CG  . LYS B 1 431 ? -10.313 21.660  -1.220  1.00 72.92  ? 431 LYS B CG  1 
ATOM   6970  C CD  . LYS B 1 431 ? -9.461  22.204  -2.359  1.00 84.79  ? 431 LYS B CD  1 
ATOM   6971  C CE  . LYS B 1 431 ? -10.191 22.137  -3.666  1.00 101.38 ? 431 LYS B CE  1 
ATOM   6972  N NZ  . LYS B 1 431 ? -9.374  22.613  -4.785  1.00 107.94 ? 431 LYS B NZ  1 
ATOM   6973  N N   . GLU B 1 432 ? -10.859 17.261  0.402   1.00 58.24  ? 432 GLU B N   1 
ATOM   6974  C CA  . GLU B 1 432 ? -10.877 15.807  0.289   1.00 60.98  ? 432 GLU B CA  1 
ATOM   6975  C C   . GLU B 1 432 ? -12.140 15.246  0.945   1.00 55.60  ? 432 GLU B C   1 
ATOM   6976  O O   . GLU B 1 432 ? -12.748 14.308  0.441   1.00 50.18  ? 432 GLU B O   1 
ATOM   6977  C CB  . GLU B 1 432 ? -9.622  15.243  0.960   1.00 66.04  ? 432 GLU B CB  1 
ATOM   6978  C CG  . GLU B 1 432 ? -9.609  13.723  1.132   1.00 75.76  ? 432 GLU B CG  1 
ATOM   6979  C CD  . GLU B 1 432 ? -8.524  13.202  2.072   1.00 81.39  ? 432 GLU B CD  1 
ATOM   6980  O OE1 . GLU B 1 432 ? -7.364  13.190  1.612   1.00 82.54  ? 432 GLU B OE1 1 
ATOM   6981  O OE2 . GLU B 1 432 ? -8.795  12.835  3.248   1.00 73.28  ? 432 GLU B OE2 1 
ATOM   6982  N N   . VAL B 1 433 ? -12.544 15.886  2.041   1.00 52.99  ? 433 VAL B N   1 
ATOM   6983  C CA  . VAL B 1 433 ? -13.481 15.351  3.016   1.00 53.27  ? 433 VAL B CA  1 
ATOM   6984  C C   . VAL B 1 433 ? -14.878 15.990  2.933   1.00 52.48  ? 433 VAL B C   1 
ATOM   6985  O O   . VAL B 1 433 ? -15.848 15.440  3.454   1.00 45.51  ? 433 VAL B O   1 
ATOM   6986  C CB  . VAL B 1 433 ? -12.756 15.676  4.339   1.00 56.29  ? 433 VAL B CB  1 
ATOM   6987  C CG1 . VAL B 1 433 ? -13.693 15.881  5.521   1.00 62.73  ? 433 VAL B CG1 1 
ATOM   6988  C CG2 . VAL B 1 433 ? -11.679 14.639  4.636   1.00 56.88  ? 433 VAL B CG2 1 
ATOM   6989  N N   . ALA B 1 434 ? -14.985 17.173  2.315   1.00 48.78  ? 434 ALA B N   1 
ATOM   6990  C CA  . ALA B 1 434 ? -16.132 18.030  2.541   1.00 50.86  ? 434 ALA B CA  1 
ATOM   6991  C C   . ALA B 1 434 ? -17.407 17.366  2.027   1.00 54.57  ? 434 ALA B C   1 
ATOM   6992  O O   . ALA B 1 434 ? -18.460 17.550  2.636   1.00 41.71  ? 434 ALA B O   1 
ATOM   6993  C CB  . ALA B 1 434 ? -15.914 19.399  1.921   1.00 48.67  ? 434 ALA B CB  1 
ATOM   6994  N N   . GLU B 1 435 ? -17.303 16.622  0.908   1.00 59.88  ? 435 GLU B N   1 
ATOM   6995  C CA  . GLU B 1 435 ? -18.460 15.986  0.286   1.00 59.47  ? 435 GLU B CA  1 
ATOM   6996  C C   . GLU B 1 435 ? -19.035 14.898  1.193   1.00 52.67  ? 435 GLU B C   1 
ATOM   6997  O O   . GLU B 1 435 ? -20.240 14.714  1.216   1.00 58.52  ? 435 GLU B O   1 
ATOM   6998  C CB  . GLU B 1 435 ? -18.114 15.447  -1.103  1.00 65.61  ? 435 GLU B CB  1 
ATOM   6999  C CG  . GLU B 1 435 ? -18.272 16.491  -2.207  1.00 69.21  ? 435 GLU B CG  1 
ATOM   7000  C CD  . GLU B 1 435 ? -19.710 16.879  -2.521  1.00 68.13  ? 435 GLU B CD  1 
ATOM   7001  O OE1 . GLU B 1 435 ? -20.637 16.190  -2.048  1.00 65.34  ? 435 GLU B OE1 1 
ATOM   7002  O OE2 . GLU B 1 435 ? -19.911 17.888  -3.227  1.00 67.79  ? 435 GLU B OE2 1 
ATOM   7003  N N   . SER B 1 436 ? -18.169 14.235  1.960   1.00 51.77  ? 436 SER B N   1 
ATOM   7004  C CA  . SER B 1 436 ? -18.519 13.214  2.940   1.00 58.03  ? 436 SER B CA  1 
ATOM   7005  C C   . SER B 1 436 ? -19.235 13.786  4.153   1.00 52.16  ? 436 SER B C   1 
ATOM   7006  O O   . SER B 1 436 ? -19.751 13.030  4.967   1.00 61.96  ? 436 SER B O   1 
ATOM   7007  C CB  . SER B 1 436 ? -17.279 12.516  3.483   1.00 64.66  ? 436 SER B CB  1 
ATOM   7008  O OG  . SER B 1 436 ? -16.117 12.834  2.732   1.00 80.28  ? 436 SER B OG  1 
ATOM   7009  N N   . LEU B 1 437 ? -19.108 15.090  4.368   1.00 50.13  ? 437 LEU B N   1 
ATOM   7010  C CA  . LEU B 1 437 ? -19.497 15.687  5.634   1.00 49.30  ? 437 LEU B CA  1 
ATOM   7011  C C   . LEU B 1 437 ? -21.010 15.895  5.646   1.00 50.70  ? 437 LEU B C   1 
ATOM   7012  O O   . LEU B 1 437 ? -21.557 16.390  4.657   1.00 41.38  ? 437 LEU B O   1 
ATOM   7013  C CB  . LEU B 1 437 ? -18.758 17.015  5.820   1.00 50.19  ? 437 LEU B CB  1 
ATOM   7014  C CG  . LEU B 1 437 ? -17.679 17.100  6.905   1.00 51.80  ? 437 LEU B CG  1 
ATOM   7015  C CD1 . LEU B 1 437 ? -16.878 15.845  7.184   1.00 49.86  ? 437 LEU B CD1 1 
ATOM   7016  C CD2 . LEU B 1 437 ? -16.747 18.238  6.527   1.00 49.25  ? 437 LEU B CD2 1 
ATOM   7017  N N   . PRO B 1 438 ? -21.713 15.545  6.754   1.00 50.11  ? 438 PRO B N   1 
ATOM   7018  C CA  . PRO B 1 438 ? -23.129 15.886  6.916   1.00 54.43  ? 438 PRO B CA  1 
ATOM   7019  C C   . PRO B 1 438 ? -23.317 17.401  6.962   1.00 53.50  ? 438 PRO B C   1 
ATOM   7020  O O   . PRO B 1 438 ? -22.405 18.094  7.396   1.00 53.85  ? 438 PRO B O   1 
ATOM   7021  C CB  . PRO B 1 438 ? -23.488 15.221  8.262   1.00 58.17  ? 438 PRO B CB  1 
ATOM   7022  C CG  . PRO B 1 438 ? -22.172 15.168  9.008   1.00 57.17  ? 438 PRO B CG  1 
ATOM   7023  C CD  . PRO B 1 438 ? -21.175 14.814  7.915   1.00 53.55  ? 438 PRO B CD  1 
ATOM   7024  N N   . VAL B 1 439 ? -24.484 17.901  6.516   1.00 49.62  ? 439 VAL B N   1 
ATOM   7025  C CA  . VAL B 1 439 ? -24.787 19.327  6.584   1.00 53.90  ? 439 VAL B CA  1 
ATOM   7026  C C   . VAL B 1 439 ? -25.430 19.612  7.943   1.00 52.94  ? 439 VAL B C   1 
ATOM   7027  O O   . VAL B 1 439 ? -26.324 18.904  8.393   1.00 54.76  ? 439 VAL B O   1 
ATOM   7028  C CB  . VAL B 1 439 ? -25.580 19.931  5.391   1.00 56.15  ? 439 VAL B CB  1 
ATOM   7029  C CG1 . VAL B 1 439 ? -26.147 18.878  4.444   1.00 60.53  ? 439 VAL B CG1 1 
ATOM   7030  C CG2 . VAL B 1 439 ? -26.649 20.946  5.806   1.00 51.80  ? 439 VAL B CG2 1 
ATOM   7031  N N   . ALA B 1 440 ? -24.930 20.659  8.603   1.00 52.56  ? 440 ALA B N   1 
ATOM   7032  C CA  . ALA B 1 440 ? -25.306 20.992  9.964   1.00 53.22  ? 440 ALA B CA  1 
ATOM   7033  C C   . ALA B 1 440 ? -26.816 21.189  10.041  1.00 55.29  ? 440 ALA B C   1 
ATOM   7034  O O   . ALA B 1 440 ? -27.373 21.911  9.216   1.00 51.98  ? 440 ALA B O   1 
ATOM   7035  C CB  . ALA B 1 440 ? -24.563 22.241  10.397  1.00 51.28  ? 440 ALA B CB  1 
ATOM   7036  N N   . GLY B 1 441 ? -27.458 20.505  11.002  1.00 58.57  ? 441 GLY B N   1 
ATOM   7037  C CA  . GLY B 1 441 ? -28.893 20.630  11.245  1.00 55.89  ? 441 GLY B CA  1 
ATOM   7038  C C   . GLY B 1 441 ? -29.772 19.639  10.468  1.00 50.34  ? 441 GLY B C   1 
ATOM   7039  O O   . GLY B 1 441 ? -30.930 19.459  10.809  1.00 48.53  ? 441 GLY B O   1 
ATOM   7040  N N   . SER B 1 442 ? -29.235 18.989  9.430   1.00 52.26  ? 442 SER B N   1 
ATOM   7041  C CA  . SER B 1 442 ? -30.036 18.222  8.479   1.00 51.77  ? 442 SER B CA  1 
ATOM   7042  C C   . SER B 1 442 ? -30.468 16.875  9.067   1.00 48.43  ? 442 SER B C   1 
ATOM   7043  O O   . SER B 1 442 ? -29.926 16.445  10.082  1.00 45.13  ? 442 SER B O   1 
ATOM   7044  C CB  . SER B 1 442 ? -29.279 18.014  7.171   1.00 49.29  ? 442 SER B CB  1 
ATOM   7045  O OG  . SER B 1 442 ? -28.153 17.156  7.342   1.00 43.55  ? 442 SER B OG  1 
ATOM   7046  N N   . LYS B 1 443 ? -31.422 16.215  8.386   1.00 45.49  ? 443 LYS B N   1 
ATOM   7047  C CA  . LYS B 1 443 ? -31.917 14.904  8.777   1.00 45.37  ? 443 LYS B CA  1 
ATOM   7048  C C   . LYS B 1 443 ? -30.755 13.907  8.781   1.00 42.04  ? 443 LYS B C   1 
ATOM   7049  O O   . LYS B 1 443 ? -30.650 13.078  9.688   1.00 44.79  ? 443 LYS B O   1 
ATOM   7050  C CB  . LYS B 1 443 ? -33.087 14.480  7.873   1.00 46.96  ? 443 LYS B CB  1 
ATOM   7051  C CG  . LYS B 1 443 ? -34.389 15.291  8.022   1.00 52.47  ? 443 LYS B CG  1 
ATOM   7052  C CD  . LYS B 1 443 ? -35.254 15.516  6.770   1.00 58.46  ? 443 LYS B CD  1 
ATOM   7053  C CE  . LYS B 1 443 ? -34.594 16.121  5.512   1.00 65.00  ? 443 LYS B CE  1 
ATOM   7054  N NZ  . LYS B 1 443 ? -33.901 17.427  5.572   1.00 66.86  ? 443 LYS B NZ  1 
ATOM   7055  N N   . LEU B 1 444 ? -29.865 14.011  7.788   1.00 42.21  ? 444 LEU B N   1 
ATOM   7056  C CA  . LEU B 1 444 ? -28.758 13.074  7.633   1.00 47.88  ? 444 LEU B CA  1 
ATOM   7057  C C   . LEU B 1 444 ? -27.779 13.183  8.799   1.00 43.61  ? 444 LEU B C   1 
ATOM   7058  O O   . LEU B 1 444 ? -27.417 12.154  9.355   1.00 41.60  ? 444 LEU B O   1 
ATOM   7059  C CB  . LEU B 1 444 ? -28.020 13.235  6.305   1.00 51.90  ? 444 LEU B CB  1 
ATOM   7060  C CG  . LEU B 1 444 ? -26.809 12.313  6.110   1.00 60.73  ? 444 LEU B CG  1 
ATOM   7061  C CD1 . LEU B 1 444 ? -27.194 10.849  6.266   1.00 59.87  ? 444 LEU B CD1 1 
ATOM   7062  C CD2 . LEU B 1 444 ? -26.159 12.555  4.750   1.00 69.54  ? 444 LEU B CD2 1 
ATOM   7063  N N   . ALA B 1 445 ? -27.366 14.417  9.150   1.00 47.55  ? 445 ALA B N   1 
ATOM   7064  C CA  . ALA B 1 445 ? -26.478 14.696  10.282  1.00 49.17  ? 445 ALA B CA  1 
ATOM   7065  C C   . ALA B 1 445 ? -27.022 14.138  11.604  1.00 46.24  ? 445 ALA B C   1 
ATOM   7066  O O   . ALA B 1 445 ? -26.269 13.578  12.399  1.00 46.84  ? 445 ALA B O   1 
ATOM   7067  C CB  . ALA B 1 445 ? -26.255 16.190  10.410  1.00 48.23  ? 445 ALA B CB  1 
ATOM   7068  N N   . ALA B 1 446 ? -28.327 14.322  11.842  1.00 43.25  ? 446 ALA B N   1 
ATOM   7069  C CA  . ALA B 1 446 ? -28.989 13.845  13.048  1.00 47.77  ? 446 ALA B CA  1 
ATOM   7070  C C   . ALA B 1 446 ? -28.941 12.316  13.130  1.00 47.14  ? 446 ALA B C   1 
ATOM   7071  O O   . ALA B 1 446 ? -28.923 11.740  14.223  1.00 44.56  ? 446 ALA B O   1 
ATOM   7072  C CB  . ALA B 1 446 ? -30.423 14.370  13.083  1.00 47.59  ? 446 ALA B CB  1 
ATOM   7073  N N   . ALA B 1 447 ? -28.935 11.666  11.961  1.00 48.57  ? 447 ALA B N   1 
ATOM   7074  C CA  . ALA B 1 447 ? -28.949 10.215  11.886  1.00 54.80  ? 447 ALA B CA  1 
ATOM   7075  C C   . ALA B 1 447 ? -27.543 9.630   12.080  1.00 55.16  ? 447 ALA B C   1 
ATOM   7076  O O   . ALA B 1 447 ? -27.405 8.445   12.371  1.00 51.13  ? 447 ALA B O   1 
ATOM   7077  C CB  . ALA B 1 447 ? -29.584 9.807   10.568  1.00 58.54  ? 447 ALA B CB  1 
ATOM   7078  N N   . LEU B 1 448 ? -26.502 10.461  11.922  1.00 66.23  ? 448 LEU B N   1 
ATOM   7079  C CA  . LEU B 1 448 ? -25.128 10.086  12.238  1.00 75.79  ? 448 LEU B CA  1 
ATOM   7080  C C   . LEU B 1 448 ? -24.719 10.648  13.604  1.00 80.80  ? 448 LEU B C   1 
ATOM   7081  O O   . LEU B 1 448 ? -23.606 11.138  13.731  1.00 75.13  ? 448 LEU B O   1 
ATOM   7082  C CB  . LEU B 1 448 ? -24.197 10.622  11.144  1.00 77.39  ? 448 LEU B CB  1 
ATOM   7083  C CG  . LEU B 1 448 ? -24.433 10.126  9.712   1.00 77.08  ? 448 LEU B CG  1 
ATOM   7084  C CD1 . LEU B 1 448 ? -23.610 10.955  8.727   1.00 75.72  ? 448 LEU B CD1 1 
ATOM   7085  C CD2 . LEU B 1 448 ? -24.110 8.646   9.561   1.00 74.37  ? 448 LEU B CD2 1 
ATOM   7086  N N   . GLU B 1 449 ? -25.595 10.551  14.622  1.00 91.47  ? 449 GLU B N   1 
ATOM   7087  C CA  . GLU B 1 449 ? -25.426 11.214  15.914  1.00 86.37  ? 449 GLU B CA  1 
ATOM   7088  C C   . GLU B 1 449 ? -25.767 12.710  15.739  1.00 79.24  ? 449 GLU B C   1 
ATOM   7089  O O   . GLU B 1 449 ? -25.359 13.527  16.605  1.00 73.16  ? 449 GLU B O   1 
ATOM   7090  C CB  . GLU B 1 449 ? -24.021 11.053  16.505  1.00 90.28  ? 449 GLU B CB  1 
ATOM   7091  C CG  . GLU B 1 449 ? -23.976 10.466  17.916  1.00 95.04  ? 449 GLU B CG  1 
ATOM   7092  C CD  . GLU B 1 449 ? -23.506 9.016   17.928  1.00 94.76  ? 449 GLU B CD  1 
ATOM   7093  O OE1 . GLU B 1 449 ? -22.271 8.765   17.982  1.00 81.15  ? 449 GLU B OE1 1 
ATOM   7094  O OE2 . GLU B 1 449 ? -24.389 8.138   17.813  1.00 89.83  ? 449 GLU B OE2 1 
ATOM   7095  N N   . MET C 1 1   ? 26.579  81.747  59.922  1.00 44.36  ? 1   MET C N   1 
ATOM   7096  C CA  . MET C 1 1   ? 26.376  80.342  60.356  1.00 41.68  ? 1   MET C CA  1 
ATOM   7097  C C   . MET C 1 1   ? 27.382  80.068  61.463  1.00 45.04  ? 1   MET C C   1 
ATOM   7098  O O   . MET C 1 1   ? 28.573  80.280  61.270  1.00 49.82  ? 1   MET C O   1 
ATOM   7099  C CB  . MET C 1 1   ? 26.574  79.360  59.200  1.00 35.88  ? 1   MET C CB  1 
ATOM   7100  C CG  . MET C 1 1   ? 26.157  77.949  59.509  1.00 33.57  ? 1   MET C CG  1 
ATOM   7101  S SD  . MET C 1 1   ? 27.035  76.838  58.397  1.00 39.96  ? 1   MET C SD  1 
ATOM   7102  C CE  . MET C 1 1   ? 26.181  75.266  58.512  1.00 39.02  ? 1   MET C CE  1 
ATOM   7103  N N   . LYS C 1 2   ? 26.866  79.634  62.616  1.00 49.04  ? 2   LYS C N   1 
ATOM   7104  C CA  . LYS C 1 2   ? 27.651  79.437  63.820  1.00 53.88  ? 2   LYS C CA  1 
ATOM   7105  C C   . LYS C 1 2   ? 28.845  78.544  63.511  1.00 43.85  ? 2   LYS C C   1 
ATOM   7106  O O   . LYS C 1 2   ? 29.971  78.872  63.865  1.00 37.07  ? 2   LYS C O   1 
ATOM   7107  C CB  . LYS C 1 2   ? 26.773  78.800  64.903  1.00 67.51  ? 2   LYS C CB  1 
ATOM   7108  C CG  . LYS C 1 2   ? 25.736  79.720  65.543  1.00 90.54  ? 2   LYS C CG  1 
ATOM   7109  C CD  . LYS C 1 2   ? 26.320  80.882  66.334  1.00 100.29 ? 2   LYS C CD  1 
ATOM   7110  C CE  . LYS C 1 2   ? 25.666  80.995  67.671  1.00 106.80 ? 2   LYS C CE  1 
ATOM   7111  N NZ  . LYS C 1 2   ? 26.513  81.791  68.559  1.00 115.16 ? 2   LYS C NZ  1 
ATOM   7112  N N   . LEU C 1 3   ? 28.583  77.430  62.828  1.00 40.78  ? 3   LEU C N   1 
ATOM   7113  C CA  . LEU C 1 3   ? 29.611  76.452  62.515  1.00 39.83  ? 3   LEU C CA  1 
ATOM   7114  C C   . LEU C 1 3   ? 30.806  77.117  61.831  1.00 40.47  ? 3   LEU C C   1 
ATOM   7115  O O   . LEU C 1 3   ? 31.940  76.731  62.088  1.00 40.35  ? 3   LEU C O   1 
ATOM   7116  C CB  . LEU C 1 3   ? 29.031  75.341  61.647  1.00 37.68  ? 3   LEU C CB  1 
ATOM   7117  C CG  . LEU C 1 3   ? 30.055  74.358  61.085  1.00 41.11  ? 3   LEU C CG  1 
ATOM   7118  C CD1 . LEU C 1 3   ? 30.871  73.735  62.210  1.00 39.78  ? 3   LEU C CD1 1 
ATOM   7119  C CD2 . LEU C 1 3   ? 29.362  73.290  60.249  1.00 43.82  ? 3   LEU C CD2 1 
ATOM   7120  N N   . LYS C 1 4   ? 30.567  78.116  60.970  1.00 40.14  ? 4   LYS C N   1 
ATOM   7121  C CA  . LYS C 1 4   ? 31.660  78.719  60.222  1.00 41.75  ? 4   LYS C CA  1 
ATOM   7122  C C   . LYS C 1 4   ? 32.362  79.782  61.076  1.00 42.89  ? 4   LYS C C   1 
ATOM   7123  O O   . LYS C 1 4   ? 33.596  79.811  61.162  1.00 45.21  ? 4   LYS C O   1 
ATOM   7124  C CB  . LYS C 1 4   ? 31.211  79.237  58.847  1.00 40.37  ? 4   LYS C CB  1 
ATOM   7125  C CG  . LYS C 1 4   ? 32.287  80.040  58.119  1.00 41.23  ? 4   LYS C CG  1 
ATOM   7126  C CD  . LYS C 1 4   ? 32.036  80.310  56.641  1.00 43.10  ? 4   LYS C CD  1 
ATOM   7127  C CE  . LYS C 1 4   ? 32.958  81.369  56.115  1.00 46.67  ? 4   LYS C CE  1 
ATOM   7128  N NZ  . LYS C 1 4   ? 33.318  81.143  54.713  1.00 51.16  ? 4   LYS C NZ  1 
ATOM   7129  N N   . GLU C 1 5   ? 31.575  80.673  61.686  1.00 41.80  ? 5   GLU C N   1 
ATOM   7130  C CA  . GLU C 1 5   ? 32.118  81.742  62.513  1.00 40.36  ? 5   GLU C CA  1 
ATOM   7131  C C   . GLU C 1 5   ? 33.026  81.138  63.574  1.00 35.19  ? 5   GLU C C   1 
ATOM   7132  O O   . GLU C 1 5   ? 34.075  81.679  63.887  1.00 30.65  ? 5   GLU C O   1 
ATOM   7133  C CB  . GLU C 1 5   ? 31.014  82.514  63.235  1.00 42.94  ? 5   GLU C CB  1 
ATOM   7134  C CG  . GLU C 1 5   ? 30.059  83.253  62.302  1.00 44.31  ? 5   GLU C CG  1 
ATOM   7135  C CD  . GLU C 1 5   ? 28.745  83.583  62.979  1.00 46.73  ? 5   GLU C CD  1 
ATOM   7136  O OE1 . GLU C 1 5   ? 27.970  84.350  62.404  1.00 57.50  ? 5   GLU C OE1 1 
ATOM   7137  O OE2 . GLU C 1 5   ? 28.487  83.088  64.082  1.00 51.35  ? 5   GLU C OE2 1 
ATOM   7138  N N   . ARG C 1 6   ? 32.603  79.995  64.112  1.00 35.22  ? 6   ARG C N   1 
ATOM   7139  C CA  . ARG C 1 6   ? 33.397  79.271  65.081  1.00 36.75  ? 6   ARG C CA  1 
ATOM   7140  C C   . ARG C 1 6   ? 34.691  78.775  64.439  1.00 34.77  ? 6   ARG C C   1 
ATOM   7141  O O   . ARG C 1 6   ? 35.753  79.051  64.986  1.00 38.29  ? 6   ARG C O   1 
ATOM   7142  C CB  . ARG C 1 6   ? 32.542  78.164  65.704  1.00 40.60  ? 6   ARG C CB  1 
ATOM   7143  C CG  . ARG C 1 6   ? 33.138  77.567  66.964  1.00 43.90  ? 6   ARG C CG  1 
ATOM   7144  C CD  . ARG C 1 6   ? 32.948  78.548  68.110  1.00 48.80  ? 6   ARG C CD  1 
ATOM   7145  N NE  . ARG C 1 6   ? 33.853  78.170  69.195  1.00 47.63  ? 6   ARG C NE  1 
ATOM   7146  C CZ  . ARG C 1 6   ? 34.878  78.912  69.573  1.00 49.23  ? 6   ARG C CZ  1 
ATOM   7147  N NH1 . ARG C 1 6   ? 35.018  80.130  69.084  1.00 55.13  ? 6   ARG C NH1 1 
ATOM   7148  N NH2 . ARG C 1 6   ? 35.748  78.448  70.447  1.00 42.23  ? 6   ARG C NH2 1 
ATOM   7149  N N   . LEU C 1 7   ? 34.613  78.046  63.305  1.00 35.05  ? 7   LEU C N   1 
ATOM   7150  C CA  . LEU C 1 7   ? 35.804  77.526  62.637  1.00 31.67  ? 7   LEU C CA  1 
ATOM   7151  C C   . LEU C 1 7   ? 36.721  78.664  62.191  1.00 33.46  ? 7   LEU C C   1 
ATOM   7152  O O   . LEU C 1 7   ? 37.932  78.492  62.142  1.00 35.85  ? 7   LEU C O   1 
ATOM   7153  C CB  . LEU C 1 7   ? 35.445  76.643  61.455  1.00 31.51  ? 7   LEU C CB  1 
ATOM   7154  C CG  . LEU C 1 7   ? 34.832  75.286  61.798  1.00 33.38  ? 7   LEU C CG  1 
ATOM   7155  C CD1 . LEU C 1 7   ? 34.328  74.636  60.555  1.00 33.39  ? 7   LEU C CD1 1 
ATOM   7156  C CD2 . LEU C 1 7   ? 35.799  74.338  62.465  1.00 37.74  ? 7   LEU C CD2 1 
ATOM   7157  N N   . ALA C 1 8   ? 36.158  79.838  61.887  1.00 34.84  ? 8   ALA C N   1 
ATOM   7158  C CA  . ALA C 1 8   ? 36.969  81.014  61.598  1.00 37.42  ? 8   ALA C CA  1 
ATOM   7159  C C   . ALA C 1 8   ? 37.863  81.404  62.780  1.00 39.08  ? 8   ALA C C   1 
ATOM   7160  O O   . ALA C 1 8   ? 38.862  82.081  62.569  1.00 41.05  ? 8   ALA C O   1 
ATOM   7161  C CB  . ALA C 1 8   ? 36.087  82.190  61.188  1.00 36.71  ? 8   ALA C CB  1 
ATOM   7162  N N   . GLU C 1 9   ? 37.508  81.017  64.019  1.00 42.24  ? 9   GLU C N   1 
ATOM   7163  C CA  . GLU C 1 9   ? 38.303  81.351  65.199  1.00 41.69  ? 9   GLU C CA  1 
ATOM   7164  C C   . GLU C 1 9   ? 39.258  80.217  65.561  1.00 39.86  ? 9   GLU C C   1 
ATOM   7165  O O   . GLU C 1 9   ? 40.409  80.484  65.899  1.00 42.33  ? 9   GLU C O   1 
ATOM   7166  C CB  . GLU C 1 9   ? 37.454  81.659  66.429  1.00 44.07  ? 9   GLU C CB  1 
ATOM   7167  C CG  . GLU C 1 9   ? 36.810  83.040  66.385  1.00 50.16  ? 9   GLU C CG  1 
ATOM   7168  C CD  . GLU C 1 9   ? 35.584  83.172  67.283  1.00 59.37  ? 9   GLU C CD  1 
ATOM   7169  O OE1 . GLU C 1 9   ? 35.221  84.336  67.626  1.00 60.94  ? 9   GLU C OE1 1 
ATOM   7170  O OE2 . GLU C 1 9   ? 34.975  82.113  67.616  1.00 52.07  ? 9   GLU C OE2 1 
ATOM   7171  N N   . LEU C 1 10  ? 38.773  78.973  65.503  1.00 33.26  ? 10  LEU C N   1 
ATOM   7172  C CA  . LEU C 1 10  ? 39.530  77.840  65.994  1.00 36.34  ? 10  LEU C CA  1 
ATOM   7173  C C   . LEU C 1 10  ? 40.625  77.398  65.026  1.00 45.39  ? 10  LEU C C   1 
ATOM   7174  O O   . LEU C 1 10  ? 41.659  76.881  65.469  1.00 46.54  ? 10  LEU C O   1 
ATOM   7175  C CB  . LEU C 1 10  ? 38.582  76.676  66.223  1.00 38.88  ? 10  LEU C CB  1 
ATOM   7176  C CG  . LEU C 1 10  ? 37.644  76.804  67.414  1.00 41.44  ? 10  LEU C CG  1 
ATOM   7177  C CD1 . LEU C 1 10  ? 36.646  75.657  67.367  1.00 42.73  ? 10  LEU C CD1 1 
ATOM   7178  C CD2 . LEU C 1 10  ? 38.458  76.787  68.706  1.00 41.43  ? 10  LEU C CD2 1 
ATOM   7179  N N   . ILE C 1 11  ? 40.353  77.470  63.711  1.00 44.56  ? 11  ILE C N   1 
ATOM   7180  C CA  . ILE C 1 11  ? 41.251  76.850  62.749  1.00 41.54  ? 11  ILE C CA  1 
ATOM   7181  C C   . ILE C 1 11  ? 42.589  77.590  62.718  1.00 35.57  ? 11  ILE C C   1 
ATOM   7182  O O   . ILE C 1 11  ? 43.615  76.940  62.714  1.00 32.02  ? 11  ILE C O   1 
ATOM   7183  C CB  . ILE C 1 11  ? 40.581  76.679  61.376  1.00 40.26  ? 11  ILE C CB  1 
ATOM   7184  C CG1 . ILE C 1 11  ? 39.835  75.347  61.360  1.00 38.65  ? 11  ILE C CG1 1 
ATOM   7185  C CG2 . ILE C 1 11  ? 41.590  76.766  60.228  1.00 38.33  ? 11  ILE C CG2 1 
ATOM   7186  C CD1 . ILE C 1 11  ? 38.865  75.191  60.214  1.00 36.85  ? 11  ILE C CD1 1 
ATOM   7187  N N   . PRO C 1 12  ? 42.652  78.940  62.764  1.00 37.47  ? 12  PRO C N   1 
ATOM   7188  C CA  . PRO C 1 12  ? 43.945  79.627  62.838  1.00 37.42  ? 12  PRO C CA  1 
ATOM   7189  C C   . PRO C 1 12  ? 44.721  79.300  64.111  1.00 40.06  ? 12  PRO C C   1 
ATOM   7190  O O   . PRO C 1 12  ? 45.937  79.190  64.060  1.00 46.09  ? 12  PRO C O   1 
ATOM   7191  C CB  . PRO C 1 12  ? 43.612  81.109  62.715  1.00 34.74  ? 12  PRO C CB  1 
ATOM   7192  C CG  . PRO C 1 12  ? 42.224  81.092  62.071  1.00 37.76  ? 12  PRO C CG  1 
ATOM   7193  C CD  . PRO C 1 12  ? 41.519  79.879  62.672  1.00 37.19  ? 12  PRO C CD  1 
ATOM   7194  N N   . GLN C 1 13  ? 44.034  79.079  65.233  1.00 37.43  ? 13  GLN C N   1 
ATOM   7195  C CA  . GLN C 1 13  ? 44.728  78.632  66.424  1.00 40.35  ? 13  GLN C CA  1 
ATOM   7196  C C   . GLN C 1 13  ? 45.364  77.271  66.191  1.00 38.11  ? 13  GLN C C   1 
ATOM   7197  O O   . GLN C 1 13  ? 46.517  77.052  66.558  1.00 42.76  ? 13  GLN C O   1 
ATOM   7198  C CB  . GLN C 1 13  ? 43.813  78.385  67.618  1.00 45.79  ? 13  GLN C CB  1 
ATOM   7199  C CG  . GLN C 1 13  ? 43.268  79.646  68.265  1.00 50.18  ? 13  GLN C CG  1 
ATOM   7200  C CD  . GLN C 1 13  ? 42.376  79.287  69.434  1.00 58.75  ? 13  GLN C CD  1 
ATOM   7201  O OE1 . GLN C 1 13  ? 42.435  78.174  69.985  1.00 53.88  ? 13  GLN C OE1 1 
ATOM   7202  N NE2 . GLN C 1 13  ? 41.549  80.243  69.824  1.00 58.20  ? 13  GLN C NE2 1 
ATOM   7203  N N   . TRP C 1 14  ? 44.562  76.345  65.652  1.00 39.51  ? 14  TRP C N   1 
ATOM   7204  C CA  . TRP C 1 14  ? 44.986  74.974  65.444  1.00 38.60  ? 14  TRP C CA  1 
ATOM   7205  C C   . TRP C 1 14  ? 46.163  74.921  64.477  1.00 40.37  ? 14  TRP C C   1 
ATOM   7206  O O   . TRP C 1 14  ? 47.083  74.118  64.645  1.00 37.00  ? 14  TRP C O   1 
ATOM   7207  C CB  . TRP C 1 14  ? 43.817  74.144  64.913  1.00 36.76  ? 14  TRP C CB  1 
ATOM   7208  C CG  . TRP C 1 14  ? 42.750  73.865  65.928  1.00 41.46  ? 14  TRP C CG  1 
ATOM   7209  C CD1 . TRP C 1 14  ? 42.883  73.897  67.287  1.00 39.17  ? 14  TRP C CD1 1 
ATOM   7210  C CD2 . TRP C 1 14  ? 41.391  73.446  65.658  1.00 41.53  ? 14  TRP C CD2 1 
ATOM   7211  N NE1 . TRP C 1 14  ? 41.694  73.578  67.876  1.00 38.28  ? 14  TRP C NE1 1 
ATOM   7212  C CE2 . TRP C 1 14  ? 40.760  73.290  66.912  1.00 40.67  ? 14  TRP C CE2 1 
ATOM   7213  C CE3 . TRP C 1 14  ? 40.650  73.205  64.497  1.00 37.45  ? 14  TRP C CE3 1 
ATOM   7214  C CZ2 . TRP C 1 14  ? 39.425  72.909  67.029  1.00 38.03  ? 14  TRP C CZ2 1 
ATOM   7215  C CZ3 . TRP C 1 14  ? 39.342  72.793  64.617  1.00 40.90  ? 14  TRP C CZ3 1 
ATOM   7216  C CH2 . TRP C 1 14  ? 38.736  72.655  65.866  1.00 40.84  ? 14  TRP C CH2 1 
ATOM   7217  N N   . ARG C 1 15  ? 46.086  75.757  63.438  1.00 39.18  ? 15  ARG C N   1 
ATOM   7218  C CA  . ARG C 1 15  ? 47.150  75.846  62.459  1.00 44.71  ? 15  ARG C CA  1 
ATOM   7219  C C   . ARG C 1 15  ? 48.449  76.281  63.144  1.00 39.21  ? 15  ARG C C   1 
ATOM   7220  O O   . ARG C 1 15  ? 49.490  75.671  62.921  1.00 38.42  ? 15  ARG C O   1 
ATOM   7221  C CB  . ARG C 1 15  ? 46.666  76.766  61.336  1.00 50.25  ? 15  ARG C CB  1 
ATOM   7222  C CG  . ARG C 1 15  ? 47.689  77.117  60.271  1.00 55.26  ? 15  ARG C CG  1 
ATOM   7223  C CD  . ARG C 1 15  ? 46.970  77.948  59.246  1.00 68.83  ? 15  ARG C CD  1 
ATOM   7224  N NE  . ARG C 1 15  ? 47.906  78.899  58.641  1.00 84.17  ? 15  ARG C NE  1 
ATOM   7225  C CZ  . ARG C 1 15  ? 47.784  80.226  58.678  1.00 100.99 ? 15  ARG C CZ  1 
ATOM   7226  N NH1 . ARG C 1 15  ? 46.771  80.799  59.325  1.00 97.69  ? 15  ARG C NH1 1 
ATOM   7227  N NH2 . ARG C 1 15  ? 48.691  80.974  58.065  1.00 102.00 ? 15  ARG C NH2 1 
ATOM   7228  N N   . ALA C 1 16  ? 48.387  77.328  63.971  1.00 36.85  ? 16  ALA C N   1 
ATOM   7229  C CA  . ALA C 1 16  ? 49.556  77.784  64.715  1.00 37.30  ? 16  ALA C CA  1 
ATOM   7230  C C   . ALA C 1 16  ? 50.119  76.676  65.607  1.00 39.29  ? 16  ALA C C   1 
ATOM   7231  O O   . ALA C 1 16  ? 51.333  76.561  65.727  1.00 45.54  ? 16  ALA C O   1 
ATOM   7232  C CB  . ALA C 1 16  ? 49.221  79.009  65.527  1.00 33.17  ? 16  ALA C CB  1 
ATOM   7233  N N   . GLU C 1 17  ? 49.238  75.867  66.209  1.00 43.34  ? 17  GLU C N   1 
ATOM   7234  C CA  . GLU C 1 17  ? 49.626  74.833  67.159  1.00 48.09  ? 17  GLU C CA  1 
ATOM   7235  C C   . GLU C 1 17  ? 50.340  73.685  66.447  1.00 44.62  ? 17  GLU C C   1 
ATOM   7236  O O   . GLU C 1 17  ? 51.220  73.034  67.019  1.00 40.47  ? 17  GLU C O   1 
ATOM   7237  C CB  . GLU C 1 17  ? 48.404  74.290  67.919  1.00 54.93  ? 17  GLU C CB  1 
ATOM   7238  C CG  . GLU C 1 17  ? 47.868  75.208  69.022  1.00 63.03  ? 17  GLU C CG  1 
ATOM   7239  C CD  . GLU C 1 17  ? 46.548  74.767  69.655  1.00 67.67  ? 17  GLU C CD  1 
ATOM   7240  O OE1 . GLU C 1 17  ? 46.386  73.539  69.874  1.00 62.83  ? 17  GLU C OE1 1 
ATOM   7241  O OE2 . GLU C 1 17  ? 45.690  75.650  69.943  1.00 66.81  ? 17  GLU C OE2 1 
ATOM   7242  N N   . VAL C 1 18  ? 49.903  73.411  65.212  1.00 43.90  ? 18  VAL C N   1 
ATOM   7243  C CA  . VAL C 1 18  ? 50.428  72.316  64.412  1.00 41.21  ? 18  VAL C CA  1 
ATOM   7244  C C   . VAL C 1 18  ? 51.780  72.738  63.847  1.00 38.55  ? 18  VAL C C   1 
ATOM   7245  O O   . VAL C 1 18  ? 52.721  71.961  63.840  1.00 42.00  ? 18  VAL C O   1 
ATOM   7246  C CB  . VAL C 1 18  ? 49.391  71.963  63.328  1.00 45.80  ? 18  VAL C CB  1 
ATOM   7247  C CG1 . VAL C 1 18  ? 49.935  71.037  62.244  1.00 46.16  ? 18  VAL C CG1 1 
ATOM   7248  C CG2 . VAL C 1 18  ? 48.131  71.366  63.942  1.00 45.79  ? 18  VAL C CG2 1 
ATOM   7249  N N   . ALA C 1 19  ? 51.884  73.995  63.418  1.00 38.91  ? 19  ALA C N   1 
ATOM   7250  C CA  . ALA C 1 19  ? 53.167  74.573  63.064  1.00 42.25  ? 19  ALA C CA  1 
ATOM   7251  C C   . ALA C 1 19  ? 54.132  74.442  64.238  1.00 39.84  ? 19  ALA C C   1 
ATOM   7252  O O   . ALA C 1 19  ? 55.264  74.034  64.035  1.00 36.15  ? 19  ALA C O   1 
ATOM   7253  C CB  . ALA C 1 19  ? 53.011  76.021  62.611  1.00 43.58  ? 19  ALA C CB  1 
ATOM   7254  N N   . GLU C 1 20  ? 53.692  74.796  65.455  1.00 46.20  ? 20  GLU C N   1 
ATOM   7255  C CA  . GLU C 1 20  ? 54.529  74.641  66.649  1.00 50.00  ? 20  GLU C CA  1 
ATOM   7256  C C   . GLU C 1 20  ? 54.906  73.172  66.873  1.00 45.27  ? 20  GLU C C   1 
ATOM   7257  O O   . GLU C 1 20  ? 56.049  72.887  67.231  1.00 37.92  ? 20  GLU C O   1 
ATOM   7258  C CB  . GLU C 1 20  ? 53.951  75.181  67.962  1.00 52.33  ? 20  GLU C CB  1 
ATOM   7259  C CG  . GLU C 1 20  ? 54.367  76.614  68.287  1.00 68.13  ? 20  GLU C CG  1 
ATOM   7260  C CD  . GLU C 1 20  ? 55.682  76.748  69.046  1.00 76.43  ? 20  GLU C CD  1 
ATOM   7261  O OE1 . GLU C 1 20  ? 55.734  76.396  70.248  1.00 80.03  ? 20  GLU C OE1 1 
ATOM   7262  O OE2 . GLU C 1 20  ? 56.667  77.197  68.425  1.00 73.81  ? 20  GLU C OE2 1 
ATOM   7263  N N   . ILE C 1 21  ? 53.968  72.239  66.653  1.00 39.89  ? 21  ILE C N   1 
ATOM   7264  C CA  . ILE C 1 21  ? 54.248  70.838  66.935  1.00 41.49  ? 21  ILE C CA  1 
ATOM   7265  C C   . ILE C 1 21  ? 55.290  70.325  65.951  1.00 43.84  ? 21  ILE C C   1 
ATOM   7266  O O   . ILE C 1 21  ? 56.175  69.566  66.344  1.00 42.43  ? 21  ILE C O   1 
ATOM   7267  C CB  . ILE C 1 21  ? 52.970  69.982  66.926  1.00 43.33  ? 21  ILE C CB  1 
ATOM   7268  C CG1 . ILE C 1 21  ? 52.105  70.312  68.130  1.00 50.83  ? 21  ILE C CG1 1 
ATOM   7269  C CG2 . ILE C 1 21  ? 53.278  68.491  66.866  1.00 40.77  ? 21  ILE C CG2 1 
ATOM   7270  C CD1 . ILE C 1 21  ? 50.617  70.176  67.879  1.00 52.30  ? 21  ILE C CD1 1 
ATOM   7271  N N   . ARG C 1 22  ? 55.193  70.758  64.688  1.00 44.47  ? 22  ARG C N   1 
ATOM   7272  C CA  . ARG C 1 22  ? 56.129  70.298  63.670  1.00 49.04  ? 22  ARG C CA  1 
ATOM   7273  C C   . ARG C 1 22  ? 57.559  70.782  63.957  1.00 47.00  ? 22  ARG C C   1 
ATOM   7274  O O   . ARG C 1 22  ? 58.499  69.978  63.979  1.00 44.90  ? 22  ARG C O   1 
ATOM   7275  C CB  . ARG C 1 22  ? 55.601  70.711  62.297  1.00 47.67  ? 22  ARG C CB  1 
ATOM   7276  C CG  . ARG C 1 22  ? 54.339  69.924  61.999  1.00 47.57  ? 22  ARG C CG  1 
ATOM   7277  C CD  . ARG C 1 22  ? 53.775  70.355  60.667  1.00 49.84  ? 22  ARG C CD  1 
ATOM   7278  N NE  . ARG C 1 22  ? 54.486  69.752  59.542  1.00 42.79  ? 22  ARG C NE  1 
ATOM   7279  C CZ  . ARG C 1 22  ? 54.463  70.260  58.328  1.00 48.06  ? 22  ARG C CZ  1 
ATOM   7280  N NH1 . ARG C 1 22  ? 53.825  71.396  58.068  1.00 48.98  ? 22  ARG C NH1 1 
ATOM   7281  N NH2 . ARG C 1 22  ? 55.102  69.633  57.360  1.00 50.47  ? 22  ARG C NH2 1 
ATOM   7282  N N   . LYS C 1 23  ? 57.708  72.084  64.221  1.00 40.51  ? 23  LYS C N   1 
ATOM   7283  C CA  . LYS C 1 23  ? 59.015  72.676  64.464  1.00 48.54  ? 23  LYS C CA  1 
ATOM   7284  C C   . LYS C 1 23  ? 59.682  72.046  65.690  1.00 46.69  ? 23  LYS C C   1 
ATOM   7285  O O   . LYS C 1 23  ? 60.822  71.581  65.619  1.00 42.58  ? 23  LYS C O   1 
ATOM   7286  C CB  . LYS C 1 23  ? 58.864  74.203  64.554  1.00 55.99  ? 23  LYS C CB  1 
ATOM   7287  C CG  . LYS C 1 23  ? 60.049  74.961  65.141  1.00 63.35  ? 23  LYS C CG  1 
ATOM   7288  C CD  . LYS C 1 23  ? 60.192  76.444  64.799  1.00 67.83  ? 23  LYS C CD  1 
ATOM   7289  C CE  . LYS C 1 23  ? 61.272  77.084  65.634  1.00 73.60  ? 23  LYS C CE  1 
ATOM   7290  N NZ  . LYS C 1 23  ? 62.079  78.065  64.902  1.00 81.35  ? 23  LYS C NZ  1 
ATOM   7291  N N   . LYS C 1 24  ? 58.940  72.028  66.801  1.00 48.36  ? 24  LYS C N   1 
ATOM   7292  C CA  . LYS C 1 24  ? 59.478  71.757  68.121  1.00 47.67  ? 24  LYS C CA  1 
ATOM   7293  C C   . LYS C 1 24  ? 59.655  70.252  68.350  1.00 43.05  ? 24  LYS C C   1 
ATOM   7294  O O   . LYS C 1 24  ? 60.669  69.817  68.907  1.00 37.32  ? 24  LYS C O   1 
ATOM   7295  C CB  . LYS C 1 24  ? 58.560  72.469  69.119  1.00 54.51  ? 24  LYS C CB  1 
ATOM   7296  C CG  . LYS C 1 24  ? 59.063  72.471  70.541  1.00 71.57  ? 24  LYS C CG  1 
ATOM   7297  C CD  . LYS C 1 24  ? 58.702  73.706  71.360  1.00 86.22  ? 24  LYS C CD  1 
ATOM   7298  C CE  . LYS C 1 24  ? 57.386  73.624  72.060  1.00 97.06  ? 24  LYS C CE  1 
ATOM   7299  N NZ  . LYS C 1 24  ? 57.413  74.466  73.259  1.00 103.79 ? 24  LYS C NZ  1 
ATOM   7300  N N   . TYR C 1 25  ? 58.690  69.450  67.890  1.00 43.08  ? 25  TYR C N   1 
ATOM   7301  C CA  . TYR C 1 25  ? 58.657  68.033  68.223  1.00 42.21  ? 25  TYR C CA  1 
ATOM   7302  C C   . TYR C 1 25  ? 58.590  67.159  66.970  1.00 40.88  ? 25  TYR C C   1 
ATOM   7303  O O   . TYR C 1 25  ? 58.270  65.969  67.077  1.00 40.77  ? 25  TYR C O   1 
ATOM   7304  C CB  . TYR C 1 25  ? 57.437  67.752  69.107  1.00 44.15  ? 25  TYR C CB  1 
ATOM   7305  C CG  . TYR C 1 25  ? 57.340  68.540  70.404  1.00 47.01  ? 25  TYR C CG  1 
ATOM   7306  C CD1 . TYR C 1 25  ? 58.389  68.571  71.313  1.00 46.92  ? 25  TYR C CD1 1 
ATOM   7307  C CD2 . TYR C 1 25  ? 56.186  69.244  70.735  1.00 53.18  ? 25  TYR C CD2 1 
ATOM   7308  C CE1 . TYR C 1 25  ? 58.299  69.269  72.508  1.00 45.12  ? 25  TYR C CE1 1 
ATOM   7309  C CE2 . TYR C 1 25  ? 56.080  69.943  71.929  1.00 52.10  ? 25  TYR C CE2 1 
ATOM   7310  C CZ  . TYR C 1 25  ? 57.141  69.953  72.821  1.00 49.92  ? 25  TYR C CZ  1 
ATOM   7311  O OH  . TYR C 1 25  ? 57.051  70.644  73.998  1.00 56.43  ? 25  TYR C OH  1 
ATOM   7312  N N   . GLY C 1 26  ? 58.886  67.733  65.788  1.00 37.05  ? 26  GLY C N   1 
ATOM   7313  C CA  . GLY C 1 26  ? 58.935  66.935  64.565  1.00 35.49  ? 26  GLY C CA  1 
ATOM   7314  C C   . GLY C 1 26  ? 59.839  65.707  64.699  1.00 33.88  ? 26  GLY C C   1 
ATOM   7315  O O   . GLY C 1 26  ? 59.451  64.613  64.305  1.00 32.93  ? 26  GLY C O   1 
ATOM   7316  N N   . ASN C 1 27  ? 61.020  65.883  65.323  1.00 39.93  ? 27  ASN C N   1 
ATOM   7317  C CA  . ASN C 1 27  ? 62.010  64.815  65.486  1.00 41.78  ? 27  ASN C CA  1 
ATOM   7318  C C   . ASN C 1 27  ? 61.737  63.902  66.701  1.00 42.71  ? 27  ASN C C   1 
ATOM   7319  O O   . ASN C 1 27  ? 62.555  63.045  67.037  1.00 44.67  ? 27  ASN C O   1 
ATOM   7320  C CB  . ASN C 1 27  ? 63.437  65.359  65.552  1.00 40.47  ? 27  ASN C CB  1 
ATOM   7321  C CG  . ASN C 1 27  ? 63.598  66.465  66.569  1.00 47.04  ? 27  ASN C CG  1 
ATOM   7322  O OD1 . ASN C 1 27  ? 64.217  67.490  66.267  1.00 61.37  ? 27  ASN C OD1 1 
ATOM   7323  N ND2 . ASN C 1 27  ? 63.042  66.304  67.759  1.00 44.06  ? 27  ASN C ND2 1 
ATOM   7324  N N   . ARG C 1 28  ? 60.592  64.015  67.372  1.00 36.84  ? 28  ARG C N   1 
ATOM   7325  C CA  . ARG C 1 28  ? 60.320  63.049  68.417  1.00 35.08  ? 28  ARG C CA  1 
ATOM   7326  C C   . ARG C 1 28  ? 59.928  61.737  67.752  1.00 32.81  ? 28  ARG C C   1 
ATOM   7327  O O   . ARG C 1 28  ? 59.115  61.721  66.848  1.00 36.84  ? 28  ARG C O   1 
ATOM   7328  C CB  . ARG C 1 28  ? 59.289  63.600  69.407  1.00 36.11  ? 28  ARG C CB  1 
ATOM   7329  C CG  . ARG C 1 28  ? 59.746  64.835  70.179  1.00 37.81  ? 28  ARG C CG  1 
ATOM   7330  C CD  . ARG C 1 28  ? 61.053  64.671  70.994  1.00 38.42  ? 28  ARG C CD  1 
ATOM   7331  N NE  . ARG C 1 28  ? 61.485  65.959  71.558  1.00 40.00  ? 28  ARG C NE  1 
ATOM   7332  C CZ  . ARG C 1 28  ? 61.454  66.306  72.857  1.00 40.04  ? 28  ARG C CZ  1 
ATOM   7333  N NH1 . ARG C 1 28  ? 61.658  67.572  73.219  1.00 36.61  ? 28  ARG C NH1 1 
ATOM   7334  N NH2 . ARG C 1 28  ? 61.175  65.394  73.783  1.00 38.12  ? 28  ARG C NH2 1 
ATOM   7335  N N   . LYS C 1 29  ? 60.516  60.639  68.222  1.00 33.56  ? 29  LYS C N   1 
ATOM   7336  C CA  . LYS C 1 29  ? 60.264  59.310  67.695  1.00 32.26  ? 29  LYS C CA  1 
ATOM   7337  C C   . LYS C 1 29  ? 59.089  58.669  68.432  1.00 34.00  ? 29  LYS C C   1 
ATOM   7338  O O   . LYS C 1 29  ? 59.048  58.716  69.657  1.00 35.99  ? 29  LYS C O   1 
ATOM   7339  C CB  . LYS C 1 29  ? 61.537  58.487  67.907  1.00 31.24  ? 29  LYS C CB  1 
ATOM   7340  C CG  . LYS C 1 29  ? 61.333  56.985  67.857  1.00 34.05  ? 29  LYS C CG  1 
ATOM   7341  C CD  . LYS C 1 29  ? 62.613  56.156  67.890  1.00 36.66  ? 29  LYS C CD  1 
ATOM   7342  C CE  . LYS C 1 29  ? 62.338  54.727  68.232  1.00 38.59  ? 29  LYS C CE  1 
ATOM   7343  N NZ  . LYS C 1 29  ? 63.493  53.884  67.968  1.00 40.16  ? 29  LYS C NZ  1 
ATOM   7344  N N   . THR C 1 30  ? 58.157  58.058  67.684  1.00 32.43  ? 30  THR C N   1 
ATOM   7345  C CA  . THR C 1 30  ? 57.024  57.336  68.245  1.00 33.74  ? 30  THR C CA  1 
ATOM   7346  C C   . THR C 1 30  ? 57.269  55.828  68.191  1.00 34.34  ? 30  THR C C   1 
ATOM   7347  O O   . THR C 1 30  ? 56.725  55.070  69.002  1.00 36.89  ? 30  THR C O   1 
ATOM   7348  C CB  . THR C 1 30  ? 55.736  57.701  67.498  1.00 34.18  ? 30  THR C CB  1 
ATOM   7349  O OG1 . THR C 1 30  ? 55.898  57.270  66.145  1.00 36.62  ? 30  THR C OG1 1 
ATOM   7350  C CG2 . THR C 1 30  ? 55.443  59.189  67.570  1.00 32.54  ? 30  THR C CG2 1 
ATOM   7351  N N   . MET C 1 31  ? 58.039  55.375  67.202  1.00 35.52  ? 31  MET C N   1 
ATOM   7352  C CA  . MET C 1 31  ? 58.242  53.943  67.026  1.00 38.55  ? 31  MET C CA  1 
ATOM   7353  C C   . MET C 1 31  ? 59.281  53.686  65.934  1.00 34.37  ? 31  MET C C   1 
ATOM   7354  O O   . MET C 1 31  ? 59.724  54.593  65.234  1.00 32.11  ? 31  MET C O   1 
ATOM   7355  C CB  . MET C 1 31  ? 56.921  53.218  66.704  1.00 37.87  ? 31  MET C CB  1 
ATOM   7356  C CG  . MET C 1 31  ? 56.174  53.804  65.496  1.00 41.07  ? 31  MET C CG  1 
ATOM   7357  S SD  . MET C 1 31  ? 54.554  53.073  65.161  1.00 35.80  ? 31  MET C SD  1 
ATOM   7358  C CE  . MET C 1 31  ? 54.903  51.327  64.911  1.00 34.28  ? 31  MET C CE  1 
ATOM   7359  N N   . ASP C 1 32  ? 59.656  52.416  65.818  1.00 33.91  ? 32  ASP C N   1 
ATOM   7360  C CA  . ASP C 1 32  ? 60.477  51.936  64.724  1.00 35.97  ? 32  ASP C CA  1 
ATOM   7361  C C   . ASP C 1 32  ? 59.600  51.542  63.533  1.00 35.84  ? 32  ASP C C   1 
ATOM   7362  O O   . ASP C 1 32  ? 58.540  50.933  63.707  1.00 32.86  ? 32  ASP C O   1 
ATOM   7363  C CB  . ASP C 1 32  ? 61.287  50.722  65.157  1.00 41.51  ? 32  ASP C CB  1 
ATOM   7364  C CG  . ASP C 1 32  ? 62.432  50.981  66.124  1.00 38.99  ? 32  ASP C CG  1 
ATOM   7365  O OD1 . ASP C 1 32  ? 62.887  52.146  66.202  1.00 41.72  ? 32  ASP C OD1 1 
ATOM   7366  O OD2 . ASP C 1 32  ? 62.858  50.007  66.765  1.00 41.15  ? 32  ASP C OD2 1 
ATOM   7367  N N   . CYS C 1 33  ? 60.083  51.900  62.330  1.00 34.68  ? 33  CYS C N   1 
ATOM   7368  C CA  . CYS C 1 33  ? 59.501  51.481  61.074  1.00 31.98  ? 33  CYS C CA  1 
ATOM   7369  C C   . CYS C 1 33  ? 60.257  50.254  60.582  1.00 32.03  ? 33  CYS C C   1 
ATOM   7370  O O   . CYS C 1 33  ? 61.465  50.298  60.439  1.00 37.43  ? 33  CYS C O   1 
ATOM   7371  C CB  . CYS C 1 33  ? 59.564  52.614  60.061  1.00 32.79  ? 33  CYS C CB  1 
ATOM   7372  S SG  . CYS C 1 33  ? 58.781  52.222  58.467  1.00 35.78  ? 33  CYS C SG  1 
ATOM   7373  N N   . THR C 1 34  ? 59.559  49.155  60.317  1.00 31.42  ? 34  THR C N   1 
ATOM   7374  C CA  . THR C 1 34  ? 60.236  47.932  59.938  1.00 34.79  ? 34  THR C CA  1 
ATOM   7375  C C   . THR C 1 34  ? 59.878  47.519  58.505  1.00 37.08  ? 34  THR C C   1 
ATOM   7376  O O   . THR C 1 34  ? 58.865  47.919  57.943  1.00 36.49  ? 34  THR C O   1 
ATOM   7377  C CB  . THR C 1 34  ? 59.880  46.825  60.928  1.00 35.55  ? 34  THR C CB  1 
ATOM   7378  O OG1 . THR C 1 34  ? 58.461  46.767  60.940  1.00 34.80  ? 34  THR C OG1 1 
ATOM   7379  C CG2 . THR C 1 34  ? 60.357  47.110  62.339  1.00 35.87  ? 34  THR C CG2 1 
ATOM   7380  N N   . ILE C 1 35  ? 60.751  46.692  57.921  1.00 39.02  ? 35  ILE C N   1 
ATOM   7381  C CA  . ILE C 1 35  ? 60.426  45.884  56.759  1.00 41.59  ? 35  ILE C CA  1 
ATOM   7382  C C   . ILE C 1 35  ? 58.992  45.381  56.901  1.00 42.96  ? 35  ILE C C   1 
ATOM   7383  O O   . ILE C 1 35  ? 58.206  45.494  55.969  1.00 40.65  ? 35  ILE C O   1 
ATOM   7384  C CB  . ILE C 1 35  ? 61.428  44.717  56.620  1.00 38.27  ? 35  ILE C CB  1 
ATOM   7385  C CG1 . ILE C 1 35  ? 62.869  45.209  56.374  1.00 39.75  ? 35  ILE C CG1 1 
ATOM   7386  C CG2 . ILE C 1 35  ? 60.984  43.714  55.557  1.00 36.71  ? 35  ILE C CG2 1 
ATOM   7387  C CD1 . ILE C 1 35  ? 63.082  45.969  55.079  1.00 38.42  ? 35  ILE C CD1 1 
ATOM   7388  N N   . GLY C 1 36  ? 58.672  44.802  58.066  1.00 43.17  ? 36  GLY C N   1 
ATOM   7389  C CA  . GLY C 1 36  ? 57.357  44.230  58.304  1.00 44.12  ? 36  GLY C CA  1 
ATOM   7390  C C   . GLY C 1 36  ? 56.220  45.189  57.930  1.00 40.64  ? 36  GLY C C   1 
ATOM   7391  O O   . GLY C 1 36  ? 55.247  44.761  57.318  1.00 35.40  ? 36  GLY C O   1 
ATOM   7392  N N   . HIS C 1 37  ? 56.368  46.471  58.300  1.00 35.08  ? 37  HIS C N   1 
ATOM   7393  C CA  . HIS C 1 37  ? 55.369  47.499  58.064  1.00 35.58  ? 37  HIS C CA  1 
ATOM   7394  C C   . HIS C 1 37  ? 55.113  47.686  56.565  1.00 33.64  ? 37  HIS C C   1 
ATOM   7395  O O   . HIS C 1 37  ? 53.967  47.905  56.174  1.00 34.03  ? 37  HIS C O   1 
ATOM   7396  C CB  . HIS C 1 37  ? 55.771  48.819  58.743  1.00 40.88  ? 37  HIS C CB  1 
ATOM   7397  C CG  . HIS C 1 37  ? 55.681  48.819  60.244  1.00 46.90  ? 37  HIS C CG  1 
ATOM   7398  N ND1 . HIS C 1 37  ? 54.624  48.267  60.936  1.00 50.55  ? 37  HIS C ND1 1 
ATOM   7399  C CD2 . HIS C 1 37  ? 56.492  49.326  61.175  1.00 44.80  ? 37  HIS C CD2 1 
ATOM   7400  C CE1 . HIS C 1 37  ? 54.826  48.413  62.233  1.00 47.16  ? 37  HIS C CE1 1 
ATOM   7401  N NE2 . HIS C 1 37  ? 55.946  49.058  62.396  1.00 45.02  ? 37  HIS C NE2 1 
ATOM   7402  N N   . ALA C 1 38  ? 56.170  47.591  55.736  1.00 32.32  ? 38  ALA C N   1 
ATOM   7403  C CA  . ALA C 1 38  ? 56.090  47.849  54.303  1.00 31.66  ? 38  ALA C CA  1 
ATOM   7404  C C   . ALA C 1 38  ? 55.340  46.720  53.599  1.00 32.97  ? 38  ALA C C   1 
ATOM   7405  O O   . ALA C 1 38  ? 54.512  46.963  52.722  1.00 38.12  ? 38  ALA C O   1 
ATOM   7406  C CB  . ALA C 1 38  ? 57.481  48.014  53.742  1.00 33.39  ? 38  ALA C CB  1 
ATOM   7407  N N   . TYR C 1 39  ? 55.618  45.487  54.021  1.00 29.58  ? 39  TYR C N   1 
ATOM   7408  C CA  . TYR C 1 39  ? 54.990  44.313  53.456  1.00 33.19  ? 39  TYR C CA  1 
ATOM   7409  C C   . TYR C 1 39  ? 53.685  43.961  54.161  1.00 34.69  ? 39  TYR C C   1 
ATOM   7410  O O   . TYR C 1 39  ? 53.055  42.970  53.784  1.00 30.30  ? 39  TYR C O   1 
ATOM   7411  C CB  . TYR C 1 39  ? 55.951  43.122  53.575  1.00 33.59  ? 39  TYR C CB  1 
ATOM   7412  C CG  . TYR C 1 39  ? 57.065  43.166  52.543  1.00 36.35  ? 39  TYR C CG  1 
ATOM   7413  C CD1 . TYR C 1 39  ? 58.228  43.875  52.801  1.00 38.62  ? 39  TYR C CD1 1 
ATOM   7414  C CD2 . TYR C 1 39  ? 56.925  42.555  51.301  1.00 36.65  ? 39  TYR C CD2 1 
ATOM   7415  C CE1 . TYR C 1 39  ? 59.243  43.947  51.867  1.00 39.05  ? 39  TYR C CE1 1 
ATOM   7416  C CE2 . TYR C 1 39  ? 57.938  42.613  50.365  1.00 37.61  ? 39  TYR C CE2 1 
ATOM   7417  C CZ  . TYR C 1 39  ? 59.098  43.310  50.652  1.00 38.29  ? 39  TYR C CZ  1 
ATOM   7418  O OH  . TYR C 1 39  ? 60.113  43.415  49.756  1.00 40.74  ? 39  TYR C OH  1 
ATOM   7419  N N   . GLY C 1 40  ? 53.338  44.721  55.215  1.00 37.43  ? 40  GLY C N   1 
ATOM   7420  C CA  . GLY C 1 40  ? 52.239  44.379  56.108  1.00 35.78  ? 40  GLY C CA  1 
ATOM   7421  C C   . GLY C 1 40  ? 51.211  45.507  56.190  1.00 37.62  ? 40  GLY C C   1 
ATOM   7422  O O   . GLY C 1 40  ? 50.541  45.686  57.202  1.00 37.00  ? 40  GLY C O   1 
ATOM   7423  N N   . GLY C 1 41  ? 51.079  46.268  55.105  1.00 36.21  ? 41  GLY C N   1 
ATOM   7424  C CA  . GLY C 1 41  ? 50.004  47.238  55.010  1.00 38.11  ? 41  GLY C CA  1 
ATOM   7425  C C   . GLY C 1 41  ? 50.157  48.356  56.040  1.00 34.98  ? 41  GLY C C   1 
ATOM   7426  O O   . GLY C 1 41  ? 49.180  48.978  56.460  1.00 32.40  ? 41  GLY C O   1 
ATOM   7427  N N   . MET C 1 42  ? 51.398  48.637  56.406  1.00 30.66  ? 42  MET C N   1 
ATOM   7428  C CA  . MET C 1 42  ? 51.648  49.694  57.362  1.00 35.63  ? 42  MET C CA  1 
ATOM   7429  C C   . MET C 1 42  ? 50.956  49.425  58.703  1.00 33.75  ? 42  MET C C   1 
ATOM   7430  O O   . MET C 1 42  ? 50.770  50.370  59.452  1.00 34.99  ? 42  MET C O   1 
ATOM   7431  C CB  . MET C 1 42  ? 51.074  51.040  56.902  1.00 34.91  ? 42  MET C CB  1 
ATOM   7432  C CG  . MET C 1 42  ? 51.516  51.565  55.578  1.00 31.85  ? 42  MET C CG  1 
ATOM   7433  S SD  . MET C 1 42  ? 51.228  53.348  55.610  1.00 32.50  ? 42  MET C SD  1 
ATOM   7434  C CE  . MET C 1 42  ? 51.554  53.765  53.891  1.00 40.92  ? 42  MET C CE  1 
ATOM   7435  N N   . ARG C 1 43  ? 50.591  48.176  59.016  1.00 34.93  ? 43  ARG C N   1 
ATOM   7436  C CA  . ARG C 1 43  ? 49.792  47.871  60.204  1.00 43.79  ? 43  ARG C CA  1 
ATOM   7437  C C   . ARG C 1 43  ? 50.545  48.260  61.474  1.00 43.45  ? 43  ARG C C   1 
ATOM   7438  O O   . ARG C 1 43  ? 51.641  47.750  61.736  1.00 45.14  ? 43  ARG C O   1 
ATOM   7439  C CB  . ARG C 1 43  ? 49.426  46.383  60.251  1.00 55.77  ? 43  ARG C CB  1 
ATOM   7440  C CG  . ARG C 1 43  ? 48.578  45.849  61.400  1.00 68.56  ? 43  ARG C CG  1 
ATOM   7441  C CD  . ARG C 1 43  ? 48.153  44.397  61.081  1.00 90.02  ? 43  ARG C CD  1 
ATOM   7442  N NE  . ARG C 1 43  ? 48.398  43.381  62.122  1.00 109.75 ? 43  ARG C NE  1 
ATOM   7443  C CZ  . ARG C 1 43  ? 49.052  42.207  62.004  1.00 108.88 ? 43  ARG C CZ  1 
ATOM   7444  N NH1 . ARG C 1 43  ? 49.595  41.826  60.856  1.00 108.35 ? 43  ARG C NH1 1 
ATOM   7445  N NH2 . ARG C 1 43  ? 49.166  41.405  63.052  1.00 104.91 ? 43  ARG C NH2 1 
ATOM   7446  N N   . GLY C 1 44  ? 49.953  49.181  62.243  1.00 38.35  ? 44  GLY C N   1 
ATOM   7447  C CA  . GLY C 1 44  ? 50.559  49.647  63.478  1.00 38.94  ? 44  GLY C CA  1 
ATOM   7448  C C   . GLY C 1 44  ? 51.263  50.985  63.292  1.00 40.49  ? 44  GLY C C   1 
ATOM   7449  O O   . GLY C 1 44  ? 51.394  51.739  64.239  1.00 49.00  ? 44  GLY C O   1 
ATOM   7450  N N   . LEU C 1 45  ? 51.677  51.323  62.069  1.00 41.31  ? 45  LEU C N   1 
ATOM   7451  C CA  . LEU C 1 45  ? 52.594  52.442  61.874  1.00 38.40  ? 45  LEU C CA  1 
ATOM   7452  C C   . LEU C 1 45  ? 51.870  53.780  62.061  1.00 37.83  ? 45  LEU C C   1 
ATOM   7453  O O   . LEU C 1 45  ? 50.873  54.045  61.399  1.00 40.72  ? 45  LEU C O   1 
ATOM   7454  C CB  . LEU C 1 45  ? 53.212  52.293  60.481  1.00 36.92  ? 45  LEU C CB  1 
ATOM   7455  C CG  . LEU C 1 45  ? 54.293  53.313  60.106  1.00 36.62  ? 45  LEU C CG  1 
ATOM   7456  C CD1 . LEU C 1 45  ? 55.584  53.193  60.930  1.00 36.72  ? 45  LEU C CD1 1 
ATOM   7457  C CD2 . LEU C 1 45  ? 54.588  53.162  58.615  1.00 35.30  ? 45  LEU C CD2 1 
ATOM   7458  N N   . LYS C 1 46  ? 52.391  54.634  62.947  1.00 35.82  ? 46  LYS C N   1 
ATOM   7459  C CA  . LYS C 1 46  ? 51.782  55.915  63.271  1.00 36.49  ? 46  LYS C CA  1 
ATOM   7460  C C   . LYS C 1 46  ? 52.117  56.976  62.221  1.00 37.61  ? 46  LYS C C   1 
ATOM   7461  O O   . LYS C 1 46  ? 52.993  57.820  62.402  1.00 32.50  ? 46  LYS C O   1 
ATOM   7462  C CB  . LYS C 1 46  ? 52.188  56.275  64.707  1.00 41.95  ? 46  LYS C CB  1 
ATOM   7463  C CG  . LYS C 1 46  ? 51.650  55.275  65.750  1.00 45.25  ? 46  LYS C CG  1 
ATOM   7464  C CD  . LYS C 1 46  ? 52.037  55.644  67.179  1.00 47.35  ? 46  LYS C CD  1 
ATOM   7465  C CE  . LYS C 1 46  ? 52.191  54.458  68.081  1.00 46.16  ? 46  LYS C CE  1 
ATOM   7466  N NZ  . LYS C 1 46  ? 51.153  54.396  69.103  1.00 45.91  ? 46  LYS C NZ  1 
ATOM   7467  N N   . ALA C 1 47  ? 51.342  56.971  61.134  1.00 43.67  ? 47  ALA C N   1 
ATOM   7468  C CA  . ALA C 1 47  ? 51.685  57.719  59.934  1.00 44.08  ? 47  ALA C CA  1 
ATOM   7469  C C   . ALA C 1 47  ? 50.706  58.863  59.633  1.00 45.97  ? 47  ALA C C   1 
ATOM   7470  O O   . ALA C 1 47  ? 50.977  59.694  58.771  1.00 40.29  ? 47  ALA C O   1 
ATOM   7471  C CB  . ALA C 1 47  ? 51.747  56.722  58.808  1.00 43.47  ? 47  ALA C CB  1 
ATOM   7472  N N   . LEU C 1 48  ? 49.560  58.904  60.332  1.00 51.25  ? 48  LEU C N   1 
ATOM   7473  C CA  . LEU C 1 48  ? 48.446  59.784  59.984  1.00 48.45  ? 48  LEU C CA  1 
ATOM   7474  C C   . LEU C 1 48  ? 47.994  60.565  61.214  1.00 41.77  ? 48  LEU C C   1 
ATOM   7475  O O   . LEU C 1 48  ? 48.007  60.054  62.331  1.00 40.65  ? 48  LEU C O   1 
ATOM   7476  C CB  . LEU C 1 48  ? 47.266  58.949  59.481  1.00 48.12  ? 48  LEU C CB  1 
ATOM   7477  C CG  . LEU C 1 48  ? 47.391  58.326  58.094  1.00 47.92  ? 48  LEU C CG  1 
ATOM   7478  C CD1 . LEU C 1 48  ? 46.279  57.328  57.878  1.00 44.88  ? 48  LEU C CD1 1 
ATOM   7479  C CD2 . LEU C 1 48  ? 47.375  59.423  57.047  1.00 52.36  ? 48  LEU C CD2 1 
ATOM   7480  N N   . VAL C 1 49  ? 47.483  61.763  60.965  1.00 36.63  ? 49  VAL C N   1 
ATOM   7481  C CA  . VAL C 1 49  ? 46.798  62.540  61.976  1.00 36.69  ? 49  VAL C CA  1 
ATOM   7482  C C   . VAL C 1 49  ? 45.279  62.515  61.773  1.00 37.95  ? 49  VAL C C   1 
ATOM   7483  O O   . VAL C 1 49  ? 44.798  62.713  60.663  1.00 36.94  ? 49  VAL C O   1 
ATOM   7484  C CB  . VAL C 1 49  ? 47.352  63.964  61.856  1.00 34.32  ? 49  VAL C CB  1 
ATOM   7485  C CG1 . VAL C 1 49  ? 46.501  64.944  62.643  1.00 34.35  ? 49  VAL C CG1 1 
ATOM   7486  C CG2 . VAL C 1 49  ? 48.813  64.022  62.283  1.00 35.35  ? 49  VAL C CG2 1 
ATOM   7487  N N   . CYS C 1 50  ? 44.525  62.366  62.873  1.00 39.57  ? 50  CYS C N   1 
ATOM   7488  C CA  . CYS C 1 50  ? 43.072  62.498  62.858  1.00 38.44  ? 50  CYS C CA  1 
ATOM   7489  C C   . CYS C 1 50  ? 42.568  62.914  64.239  1.00 33.48  ? 50  CYS C C   1 
ATOM   7490  O O   . CYS C 1 50  ? 42.833  62.240  65.223  1.00 28.09  ? 50  CYS C O   1 
ATOM   7491  C CB  . CYS C 1 50  ? 42.414  61.195  62.410  1.00 41.17  ? 50  CYS C CB  1 
ATOM   7492  S SG  . CYS C 1 50  ? 40.634  61.133  62.725  1.00 36.22  ? 50  CYS C SG  1 
ATOM   7493  N N   . ASP C 1 51  ? 41.808  64.010  64.265  1.00 35.60  ? 51  ASP C N   1 
ATOM   7494  C CA  . ASP C 1 51  ? 41.450  64.720  65.484  1.00 39.38  ? 51  ASP C CA  1 
ATOM   7495  C C   . ASP C 1 51  ? 39.948  64.626  65.775  1.00 40.48  ? 51  ASP C C   1 
ATOM   7496  O O   . ASP C 1 51  ? 39.480  65.103  66.810  1.00 43.21  ? 51  ASP C O   1 
ATOM   7497  C CB  . ASP C 1 51  ? 41.952  66.160  65.407  1.00 41.44  ? 51  ASP C CB  1 
ATOM   7498  C CG  . ASP C 1 51  ? 43.441  66.348  65.702  1.00 37.15  ? 51  ASP C CG  1 
ATOM   7499  O OD1 . ASP C 1 51  ? 44.001  65.492  66.405  1.00 32.99  ? 51  ASP C OD1 1 
ATOM   7500  O OD2 . ASP C 1 51  ? 44.034  67.324  65.186  1.00 34.64  ? 51  ASP C OD2 1 
ATOM   7501  N N   . THR C 1 52  ? 39.210  63.940  64.897  1.00 38.31  ? 52  THR C N   1 
ATOM   7502  C CA  . THR C 1 52  ? 37.760  63.871  64.948  1.00 32.19  ? 52  THR C CA  1 
ATOM   7503  C C   . THR C 1 52  ? 37.337  62.671  65.789  1.00 28.75  ? 52  THR C C   1 
ATOM   7504  O O   . THR C 1 52  ? 36.347  62.684  66.473  1.00 33.97  ? 52  THR C O   1 
ATOM   7505  C CB  . THR C 1 52  ? 37.245  63.816  63.503  1.00 29.52  ? 52  THR C CB  1 
ATOM   7506  O OG1 . THR C 1 52  ? 37.790  62.661  62.865  1.00 27.10  ? 52  THR C OG1 1 
ATOM   7507  C CG2 . THR C 1 52  ? 37.654  65.057  62.726  1.00 28.35  ? 52  THR C CG2 1 
ATOM   7508  N N   . SER C 1 53  ? 38.080  61.594  65.745  1.00 31.19  ? 53  SER C N   1 
ATOM   7509  C CA  . SER C 1 53  ? 37.723  60.429  66.521  1.00 32.23  ? 53  SER C CA  1 
ATOM   7510  C C   . SER C 1 53  ? 39.005  59.679  66.859  1.00 34.85  ? 53  SER C C   1 
ATOM   7511  O O   . SER C 1 53  ? 40.037  59.866  66.198  1.00 38.69  ? 53  SER C O   1 
ATOM   7512  C CB  . SER C 1 53  ? 36.721  59.567  65.803  1.00 34.30  ? 53  SER C CB  1 
ATOM   7513  O OG  . SER C 1 53  ? 37.181  59.160  64.522  1.00 32.91  ? 53  SER C OG  1 
ATOM   7514  N N   . GLU C 1 54  ? 38.917  58.883  67.928  1.00 35.85  ? 54  GLU C N   1 
ATOM   7515  C CA  . GLU C 1 54  ? 40.053  58.211  68.540  1.00 37.71  ? 54  GLU C CA  1 
ATOM   7516  C C   . GLU C 1 54  ? 39.510  56.933  69.160  1.00 37.64  ? 54  GLU C C   1 
ATOM   7517  O O   . GLU C 1 54  ? 38.456  56.961  69.797  1.00 37.47  ? 54  GLU C O   1 
ATOM   7518  C CB  . GLU C 1 54  ? 40.742  59.124  69.562  1.00 42.56  ? 54  GLU C CB  1 
ATOM   7519  C CG  . GLU C 1 54  ? 41.929  58.485  70.291  1.00 44.62  ? 54  GLU C CG  1 
ATOM   7520  C CD  . GLU C 1 54  ? 42.797  59.361  71.191  1.00 48.97  ? 54  GLU C CD  1 
ATOM   7521  O OE1 . GLU C 1 54  ? 43.621  58.654  71.804  1.00 62.74  ? 54  GLU C OE1 1 
ATOM   7522  O OE2 . GLU C 1 54  ? 42.735  60.622  71.325  1.00 44.86  ? 54  GLU C OE2 1 
ATOM   7523  N N   . VAL C 1 55  ? 40.188  55.812  68.922  1.00 37.32  ? 55  VAL C N   1 
ATOM   7524  C CA  . VAL C 1 55  ? 39.765  54.560  69.524  1.00 43.23  ? 55  VAL C CA  1 
ATOM   7525  C C   . VAL C 1 55  ? 40.578  54.361  70.800  1.00 47.65  ? 55  VAL C C   1 
ATOM   7526  O O   . VAL C 1 55  ? 41.804  54.345  70.730  1.00 49.77  ? 55  VAL C O   1 
ATOM   7527  C CB  . VAL C 1 55  ? 39.954  53.410  68.525  1.00 45.00  ? 55  VAL C CB  1 
ATOM   7528  C CG1 . VAL C 1 55  ? 39.506  52.068  69.086  1.00 47.13  ? 55  VAL C CG1 1 
ATOM   7529  C CG2 . VAL C 1 55  ? 39.238  53.708  67.218  1.00 45.63  ? 55  VAL C CG2 1 
ATOM   7530  N N   . PHE C 1 56  ? 39.893  54.276  71.958  1.00 51.36  ? 56  PHE C N   1 
ATOM   7531  C CA  . PHE C 1 56  ? 40.493  53.846  73.223  1.00 47.96  ? 56  PHE C CA  1 
ATOM   7532  C C   . PHE C 1 56  ? 40.241  52.348  73.373  1.00 50.48  ? 56  PHE C C   1 
ATOM   7533  O O   . PHE C 1 56  ? 39.094  51.926  73.340  1.00 59.33  ? 56  PHE C O   1 
ATOM   7534  C CB  . PHE C 1 56  ? 39.925  54.662  74.389  1.00 47.24  ? 56  PHE C CB  1 
ATOM   7535  C CG  . PHE C 1 56  ? 40.189  56.163  74.321  1.00 43.02  ? 56  PHE C CG  1 
ATOM   7536  C CD1 . PHE C 1 56  ? 39.488  56.984  73.438  1.00 46.48  ? 56  PHE C CD1 1 
ATOM   7537  C CD2 . PHE C 1 56  ? 41.149  56.756  75.124  1.00 45.16  ? 56  PHE C CD2 1 
ATOM   7538  C CE1 . PHE C 1 56  ? 39.743  58.358  73.360  1.00 46.62  ? 56  PHE C CE1 1 
ATOM   7539  C CE2 . PHE C 1 56  ? 41.402  58.133  75.051  1.00 53.59  ? 56  PHE C CE2 1 
ATOM   7540  C CZ  . PHE C 1 56  ? 40.693  58.937  74.170  1.00 49.14  ? 56  PHE C CZ  1 
ATOM   7541  N N   . PRO C 1 57  ? 41.263  51.463  73.455  1.00 64.08  ? 57  PRO C N   1 
ATOM   7542  C CA  . PRO C 1 57  ? 40.998  50.016  73.337  1.00 71.12  ? 57  PRO C CA  1 
ATOM   7543  C C   . PRO C 1 57  ? 40.222  49.407  74.519  1.00 69.47  ? 57  PRO C C   1 
ATOM   7544  O O   . PRO C 1 57  ? 39.651  48.310  74.409  1.00 64.07  ? 57  PRO C O   1 
ATOM   7545  C CB  . PRO C 1 57  ? 42.416  49.410  73.145  1.00 76.32  ? 57  PRO C CB  1 
ATOM   7546  C CG  . PRO C 1 57  ? 43.333  50.615  72.873  1.00 73.41  ? 57  PRO C CG  1 
ATOM   7547  C CD  . PRO C 1 57  ? 42.695  51.789  73.612  1.00 63.52  ? 57  PRO C CD  1 
ATOM   7548  N N   . ASP C 1 58  ? 40.180  50.165  75.629  1.00 62.67  ? 58  ASP C N   1 
ATOM   7549  C CA  . ASP C 1 58  ? 39.304  49.907  76.769  1.00 79.84  ? 58  ASP C CA  1 
ATOM   7550  C C   . ASP C 1 58  ? 37.824  50.247  76.488  1.00 81.50  ? 58  ASP C C   1 
ATOM   7551  O O   . ASP C 1 58  ? 36.965  49.367  76.622  1.00 71.18  ? 58  ASP C O   1 
ATOM   7552  C CB  . ASP C 1 58  ? 39.843  50.620  78.005  1.00 75.18  ? 58  ASP C CB  1 
ATOM   7553  C CG  . ASP C 1 58  ? 41.091  50.006  78.631  1.00 72.56  ? 58  ASP C CG  1 
ATOM   7554  O OD1 . ASP C 1 58  ? 41.307  48.768  78.469  1.00 64.71  ? 58  ASP C OD1 1 
ATOM   7555  O OD2 . ASP C 1 58  ? 41.862  50.778  79.247  1.00 66.84  ? 58  ASP C OD2 1 
ATOM   7556  N N   . GLU C 1 59  ? 37.535  51.508  76.088  1.00 69.48  ? 59  GLU C N   1 
ATOM   7557  C CA  . GLU C 1 59  ? 36.201  52.109  76.117  1.00 59.86  ? 59  GLU C CA  1 
ATOM   7558  C C   . GLU C 1 59  ? 35.435  52.023  74.784  1.00 60.80  ? 59  GLU C C   1 
ATOM   7559  O O   . GLU C 1 59  ? 34.223  51.785  74.786  1.00 59.20  ? 59  GLU C O   1 
ATOM   7560  C CB  . GLU C 1 59  ? 36.337  53.575  76.532  1.00 54.10  ? 59  GLU C CB  1 
ATOM   7561  C CG  . GLU C 1 59  ? 37.152  53.794  77.801  1.00 52.41  ? 59  GLU C CG  1 
ATOM   7562  C CD  . GLU C 1 59  ? 37.215  55.260  78.218  1.00 59.90  ? 59  GLU C CD  1 
ATOM   7563  O OE1 . GLU C 1 59  ? 36.107  55.796  78.527  1.00 54.17  ? 59  GLU C OE1 1 
ATOM   7564  O OE2 . GLU C 1 59  ? 38.341  55.865  78.245  1.00 56.78  ? 59  GLU C OE2 1 
ATOM   7565  N N   . GLY C 1 60  ? 36.122  52.259  73.650  1.00 59.46  ? 60  GLY C N   1 
ATOM   7566  C CA  . GLY C 1 60  ? 35.529  52.230  72.314  1.00 53.40  ? 60  GLY C CA  1 
ATOM   7567  C C   . GLY C 1 60  ? 35.858  53.521  71.564  1.00 48.82  ? 60  GLY C C   1 
ATOM   7568  O O   . GLY C 1 60  ? 36.640  54.329  72.064  1.00 44.96  ? 60  GLY C O   1 
ATOM   7569  N N   . VAL C 1 61  ? 35.244  53.745  70.392  1.00 45.18  ? 61  VAL C N   1 
ATOM   7570  C CA  . VAL C 1 61  ? 35.507  54.978  69.653  1.00 41.64  ? 61  VAL C CA  1 
ATOM   7571  C C   . VAL C 1 61  ? 34.895  56.154  70.415  1.00 34.98  ? 61  VAL C C   1 
ATOM   7572  O O   . VAL C 1 61  ? 33.839  56.035  71.004  1.00 38.06  ? 61  VAL C O   1 
ATOM   7573  C CB  . VAL C 1 61  ? 35.083  54.977  68.163  1.00 42.18  ? 61  VAL C CB  1 
ATOM   7574  C CG1 . VAL C 1 61  ? 33.593  54.798  67.932  1.00 45.13  ? 61  VAL C CG1 1 
ATOM   7575  C CG2 . VAL C 1 61  ? 35.533  56.247  67.455  1.00 46.17  ? 61  VAL C CG2 1 
ATOM   7576  N N   . LYS C 1 62  ? 35.577  57.294  70.427  1.00 33.44  ? 62  LYS C N   1 
ATOM   7577  C CA  . LYS C 1 62  ? 35.000  58.504  70.973  1.00 36.41  ? 62  LYS C CA  1 
ATOM   7578  C C   . LYS C 1 62  ? 35.137  59.643  69.961  1.00 36.39  ? 62  LYS C C   1 
ATOM   7579  O O   . LYS C 1 62  ? 36.192  59.799  69.341  1.00 35.71  ? 62  LYS C O   1 
ATOM   7580  C CB  . LYS C 1 62  ? 35.696  58.943  72.268  1.00 44.96  ? 62  LYS C CB  1 
ATOM   7581  C CG  . LYS C 1 62  ? 35.788  57.940  73.426  1.00 47.80  ? 62  LYS C CG  1 
ATOM   7582  C CD  . LYS C 1 62  ? 36.357  58.635  74.669  1.00 52.58  ? 62  LYS C CD  1 
ATOM   7583  C CE  . LYS C 1 62  ? 36.679  57.767  75.866  1.00 52.51  ? 62  LYS C CE  1 
ATOM   7584  N NZ  . LYS C 1 62  ? 37.591  58.450  76.799  1.00 52.34  ? 62  LYS C NZ  1 
ATOM   7585  N N   . PHE C 1 63  ? 34.090  60.480  69.880  1.00 33.11  ? 63  PHE C N   1 
ATOM   7586  C CA  . PHE C 1 63  ? 34.028  61.601  68.963  1.00 31.27  ? 63  PHE C CA  1 
ATOM   7587  C C   . PHE C 1 63  ? 34.467  62.839  69.717  1.00 32.55  ? 63  PHE C C   1 
ATOM   7588  O O   . PHE C 1 63  ? 33.753  63.249  70.620  1.00 39.47  ? 63  PHE C O   1 
ATOM   7589  C CB  . PHE C 1 63  ? 32.610  61.807  68.410  1.00 27.66  ? 63  PHE C CB  1 
ATOM   7590  C CG  . PHE C 1 63  ? 32.022  60.599  67.700  1.00 24.98  ? 63  PHE C CG  1 
ATOM   7591  C CD1 . PHE C 1 63  ? 32.799  59.805  66.877  1.00 23.83  ? 63  PHE C CD1 1 
ATOM   7592  C CD2 . PHE C 1 63  ? 30.693  60.235  67.883  1.00 26.38  ? 63  PHE C CD2 1 
ATOM   7593  C CE1 . PHE C 1 63  ? 32.270  58.681  66.260  1.00 23.68  ? 63  PHE C CE1 1 
ATOM   7594  C CE2 . PHE C 1 63  ? 30.158  59.133  67.236  1.00 24.50  ? 63  PHE C CE2 1 
ATOM   7595  C CZ  . PHE C 1 63  ? 30.952  58.358  66.424  1.00 24.55  ? 63  PHE C CZ  1 
ATOM   7596  N N   . ARG C 1 64  ? 35.612  63.417  69.342  1.00 29.09  ? 64  ARG C N   1 
ATOM   7597  C CA  . ARG C 1 64  ? 36.170  64.576  70.024  1.00 31.64  ? 64  ARG C CA  1 
ATOM   7598  C C   . ARG C 1 64  ? 36.152  64.473  71.562  1.00 33.29  ? 64  ARG C C   1 
ATOM   7599  O O   . ARG C 1 64  ? 35.905  65.472  72.255  1.00 31.91  ? 64  ARG C O   1 
ATOM   7600  C CB  . ARG C 1 64  ? 35.372  65.775  69.523  1.00 32.27  ? 64  ARG C CB  1 
ATOM   7601  C CG  . ARG C 1 64  ? 35.739  66.176  68.106  1.00 39.23  ? 64  ARG C CG  1 
ATOM   7602  C CD  . ARG C 1 64  ? 37.063  66.923  68.033  1.00 38.58  ? 64  ARG C CD  1 
ATOM   7603  N NE  . ARG C 1 64  ? 37.169  67.652  66.764  1.00 40.84  ? 64  ARG C NE  1 
ATOM   7604  C CZ  . ARG C 1 64  ? 38.157  68.486  66.480  1.00 37.57  ? 64  ARG C CZ  1 
ATOM   7605  N NH1 . ARG C 1 64  ? 39.126  68.579  67.352  1.00 37.44  ? 64  ARG C NH1 1 
ATOM   7606  N NH2 . ARG C 1 64  ? 38.187  69.224  65.372  1.00 31.70  ? 64  ARG C NH2 1 
ATOM   7607  N N   . GLY C 1 65  ? 36.433  63.279  72.112  1.00 33.17  ? 65  GLY C N   1 
ATOM   7608  C CA  . GLY C 1 65  ? 36.574  63.131  73.555  1.00 36.66  ? 65  GLY C CA  1 
ATOM   7609  C C   . GLY C 1 65  ? 35.360  62.494  74.234  1.00 40.15  ? 65  GLY C C   1 
ATOM   7610  O O   . GLY C 1 65  ? 35.509  61.916  75.323  1.00 35.92  ? 65  GLY C O   1 
ATOM   7611  N N   . TYR C 1 66  ? 34.190  62.568  73.561  1.00 39.19  ? 66  TYR C N   1 
ATOM   7612  C CA  . TYR C 1 66  ? 32.899  62.166  74.117  1.00 33.02  ? 66  TYR C CA  1 
ATOM   7613  C C   . TYR C 1 66  ? 32.538  60.740  73.743  1.00 31.28  ? 66  TYR C C   1 
ATOM   7614  O O   . TYR C 1 66  ? 32.707  60.342  72.611  1.00 36.91  ? 66  TYR C O   1 
ATOM   7615  C CB  . TYR C 1 66  ? 31.772  63.028  73.564  1.00 29.24  ? 66  TYR C CB  1 
ATOM   7616  C CG  . TYR C 1 66  ? 31.862  64.453  74.058  1.00 27.06  ? 66  TYR C CG  1 
ATOM   7617  C CD1 . TYR C 1 66  ? 31.348  64.805  75.291  1.00 27.87  ? 66  TYR C CD1 1 
ATOM   7618  C CD2 . TYR C 1 66  ? 32.488  65.422  73.305  1.00 28.34  ? 66  TYR C CD2 1 
ATOM   7619  C CE1 . TYR C 1 66  ? 31.435  66.103  75.750  1.00 30.01  ? 66  TYR C CE1 1 
ATOM   7620  C CE2 . TYR C 1 66  ? 32.598  66.724  73.753  1.00 29.34  ? 66  TYR C CE2 1 
ATOM   7621  C CZ  . TYR C 1 66  ? 32.080  67.060  74.989  1.00 30.51  ? 66  TYR C CZ  1 
ATOM   7622  O OH  . TYR C 1 66  ? 32.188  68.347  75.429  1.00 34.64  ? 66  TYR C OH  1 
ATOM   7623  N N   . THR C 1 67  ? 31.977  59.991  74.680  1.00 33.28  ? 67  THR C N   1 
ATOM   7624  C CA  . THR C 1 67  ? 31.528  58.642  74.380  1.00 35.62  ? 67  THR C CA  1 
ATOM   7625  C C   . THR C 1 67  ? 30.213  58.715  73.626  1.00 34.06  ? 67  THR C C   1 
ATOM   7626  O O   . THR C 1 67  ? 29.514  59.715  73.631  1.00 36.12  ? 67  THR C O   1 
ATOM   7627  C CB  . THR C 1 67  ? 31.358  57.797  75.647  1.00 38.23  ? 67  THR C CB  1 
ATOM   7628  O OG1 . THR C 1 67  ? 30.318  58.438  76.376  1.00 38.36  ? 67  THR C OG1 1 
ATOM   7629  C CG2 . THR C 1 67  ? 32.625  57.715  76.482  1.00 38.24  ? 67  THR C CG2 1 
ATOM   7630  N N   . ILE C 1 68  ? 29.868  57.584  73.044  1.00 34.55  ? 68  ILE C N   1 
ATOM   7631  C CA  . ILE C 1 68  ? 28.668  57.451  72.267  1.00 34.75  ? 68  ILE C CA  1 
ATOM   7632  C C   . ILE C 1 68  ? 27.449  57.539  73.176  1.00 38.82  ? 68  ILE C C   1 
ATOM   7633  O O   . ILE C 1 68  ? 26.600  58.404  72.973  1.00 40.07  ? 68  ILE C O   1 
ATOM   7634  C CB  . ILE C 1 68  ? 28.800  56.180  71.420  1.00 34.46  ? 68  ILE C CB  1 
ATOM   7635  C CG1 . ILE C 1 68  ? 29.621  56.570  70.191  1.00 35.87  ? 68  ILE C CG1 1 
ATOM   7636  C CG2 . ILE C 1 68  ? 27.445  55.534  71.088  1.00 37.70  ? 68  ILE C CG2 1 
ATOM   7637  C CD1 . ILE C 1 68  ? 29.812  55.469  69.179  1.00 38.69  ? 68  ILE C CD1 1 
ATOM   7638  N N   . PRO C 1 69  ? 27.360  56.728  74.249  1.00 43.36  ? 69  PRO C N   1 
ATOM   7639  C CA  . PRO C 1 69  ? 26.245  56.857  75.185  1.00 37.50  ? 69  PRO C CA  1 
ATOM   7640  C C   . PRO C 1 69  ? 26.012  58.311  75.614  1.00 35.54  ? 69  PRO C C   1 
ATOM   7641  O O   . PRO C 1 69  ? 24.910  58.810  75.503  1.00 33.97  ? 69  PRO C O   1 
ATOM   7642  C CB  . PRO C 1 69  ? 26.760  55.972  76.322  1.00 37.86  ? 69  PRO C CB  1 
ATOM   7643  C CG  . PRO C 1 69  ? 27.545  54.912  75.613  1.00 43.33  ? 69  PRO C CG  1 
ATOM   7644  C CD  . PRO C 1 69  ? 28.370  55.741  74.674  1.00 41.36  ? 69  PRO C CD  1 
ATOM   7645  N N   . GLU C 1 70  ? 27.059  58.990  76.098  1.00 34.36  ? 70  GLU C N   1 
ATOM   7646  C CA  . GLU C 1 70  ? 27.002  60.375  76.533  1.00 36.18  ? 70  GLU C CA  1 
ATOM   7647  C C   . GLU C 1 70  ? 26.247  61.301  75.589  1.00 36.76  ? 70  GLU C C   1 
ATOM   7648  O O   . GLU C 1 70  ? 25.704  62.314  76.033  1.00 39.55  ? 70  GLU C O   1 
ATOM   7649  C CB  . GLU C 1 70  ? 28.377  61.030  76.418  1.00 39.17  ? 70  GLU C CB  1 
ATOM   7650  C CG  . GLU C 1 70  ? 29.203  60.923  77.685  1.00 40.95  ? 70  GLU C CG  1 
ATOM   7651  C CD  . GLU C 1 70  ? 30.572  61.515  77.518  1.00 39.64  ? 70  GLU C CD  1 
ATOM   7652  O OE1 . GLU C 1 70  ? 30.687  62.769  77.501  1.00 41.29  ? 70  GLU C OE1 1 
ATOM   7653  O OE2 . GLU C 1 70  ? 31.494  60.673  77.396  1.00 41.57  ? 70  GLU C OE2 1 
ATOM   7654  N N   . LEU C 1 71  ? 26.399  61.035  74.285  1.00 39.01  ? 71  LEU C N   1 
ATOM   7655  C CA  . LEU C 1 71  ? 25.899  61.886  73.215  1.00 35.48  ? 71  LEU C CA  1 
ATOM   7656  C C   . LEU C 1 71  ? 24.493  61.441  72.814  1.00 33.60  ? 71  LEU C C   1 
ATOM   7657  O O   . LEU C 1 71  ? 23.726  62.218  72.263  1.00 39.12  ? 71  LEU C O   1 
ATOM   7658  C CB  . LEU C 1 71  ? 26.888  61.786  72.053  1.00 38.23  ? 71  LEU C CB  1 
ATOM   7659  C CG  . LEU C 1 71  ? 28.281  62.401  72.254  1.00 35.12  ? 71  LEU C CG  1 
ATOM   7660  C CD1 . LEU C 1 71  ? 29.168  62.065  71.056  1.00 35.68  ? 71  LEU C CD1 1 
ATOM   7661  C CD2 . LEU C 1 71  ? 28.216  63.902  72.436  1.00 35.39  ? 71  LEU C CD2 1 
ATOM   7662  N N   . ARG C 1 72  ? 24.141  60.199  73.133  1.00 32.59  ? 72  ARG C N   1 
ATOM   7663  C CA  . ARG C 1 72  ? 22.829  59.648  72.832  1.00 36.67  ? 72  ARG C CA  1 
ATOM   7664  C C   . ARG C 1 72  ? 21.802  59.875  73.955  1.00 41.33  ? 72  ARG C C   1 
ATOM   7665  O O   . ARG C 1 72  ? 20.599  59.863  73.679  1.00 37.38  ? 72  ARG C O   1 
ATOM   7666  C CB  . ARG C 1 72  ? 23.041  58.161  72.528  1.00 37.19  ? 72  ARG C CB  1 
ATOM   7667  C CG  . ARG C 1 72  ? 21.773  57.444  72.119  1.00 35.76  ? 72  ARG C CG  1 
ATOM   7668  C CD  . ARG C 1 72  ? 22.092  56.325  71.184  1.00 36.85  ? 72  ARG C CD  1 
ATOM   7669  N NE  . ARG C 1 72  ? 20.868  55.537  70.994  1.00 37.16  ? 72  ARG C NE  1 
ATOM   7670  C CZ  . ARG C 1 72  ? 20.327  54.734  71.895  1.00 39.68  ? 72  ARG C CZ  1 
ATOM   7671  N NH1 . ARG C 1 72  ? 20.976  54.436  73.011  1.00 42.44  ? 72  ARG C NH1 1 
ATOM   7672  N NH2 . ARG C 1 72  ? 19.139  54.201  71.666  1.00 44.66  ? 72  ARG C NH2 1 
ATOM   7673  N N   . GLU C 1 73  ? 22.245  60.090  75.212  1.00 44.48  ? 73  GLU C N   1 
ATOM   7674  C CA  . GLU C 1 73  ? 21.323  60.233  76.334  1.00 42.72  ? 73  GLU C CA  1 
ATOM   7675  C C   . GLU C 1 73  ? 21.992  60.935  77.511  1.00 40.69  ? 73  GLU C C   1 
ATOM   7676  O O   . GLU C 1 73  ? 23.119  60.618  77.866  1.00 47.97  ? 73  GLU C O   1 
ATOM   7677  C CB  . GLU C 1 73  ? 20.839  58.840  76.731  1.00 45.99  ? 73  GLU C CB  1 
ATOM   7678  C CG  . GLU C 1 73  ? 19.485  58.810  77.441  1.00 49.32  ? 73  GLU C CG  1 
ATOM   7679  C CD  . GLU C 1 73  ? 19.003  57.380  77.693  1.00 57.04  ? 73  GLU C CD  1 
ATOM   7680  O OE1 . GLU C 1 73  ? 19.784  56.418  77.396  1.00 56.77  ? 73  GLU C OE1 1 
ATOM   7681  O OE2 . GLU C 1 73  ? 17.843  57.224  78.164  1.00 48.42  ? 73  GLU C OE2 1 
ATOM   7682  N N   . GLY C 1 74  ? 21.293  61.884  78.136  1.00 35.59  ? 74  GLY C N   1 
ATOM   7683  C CA  . GLY C 1 74  ? 21.795  62.496  79.355  1.00 36.17  ? 74  GLY C CA  1 
ATOM   7684  C C   . GLY C 1 74  ? 22.211  63.946  79.112  1.00 37.06  ? 74  GLY C C   1 
ATOM   7685  O O   . GLY C 1 74  ? 21.896  64.522  78.087  1.00 37.87  ? 74  GLY C O   1 
ATOM   7686  N N   . PRO C 1 75  ? 22.900  64.624  80.052  1.00 36.75  ? 75  PRO C N   1 
ATOM   7687  C CA  . PRO C 1 75  ? 23.183  66.045  79.870  1.00 35.32  ? 75  PRO C CA  1 
ATOM   7688  C C   . PRO C 1 75  ? 24.102  66.387  78.702  1.00 36.59  ? 75  PRO C C   1 
ATOM   7689  O O   . PRO C 1 75  ? 24.239  67.558  78.390  1.00 27.96  ? 75  PRO C O   1 
ATOM   7690  C CB  . PRO C 1 75  ? 23.778  66.520  81.216  1.00 35.01  ? 75  PRO C CB  1 
ATOM   7691  C CG  . PRO C 1 75  ? 23.987  65.273  82.037  1.00 34.45  ? 75  PRO C CG  1 
ATOM   7692  C CD  . PRO C 1 75  ? 23.361  64.086  81.341  1.00 34.45  ? 75  PRO C CD  1 
ATOM   7693  N N   . HIS C 1 76  ? 24.769  65.377  78.116  1.00 42.78  ? 76  HIS C N   1 
ATOM   7694  C CA  . HIS C 1 76  ? 25.679  65.591  76.996  1.00 48.29  ? 76  HIS C CA  1 
ATOM   7695  C C   . HIS C 1 76  ? 25.001  65.243  75.657  1.00 47.24  ? 76  HIS C C   1 
ATOM   7696  O O   . HIS C 1 76  ? 25.639  65.254  74.607  1.00 44.62  ? 76  HIS C O   1 
ATOM   7697  C CB  . HIS C 1 76  ? 27.016  64.882  77.271  1.00 47.47  ? 76  HIS C CB  1 
ATOM   7698  C CG  . HIS C 1 76  ? 27.928  65.579  78.250  1.00 48.36  ? 76  HIS C CG  1 
ATOM   7699  N ND1 . HIS C 1 76  ? 29.031  64.956  78.800  1.00 48.93  ? 76  HIS C ND1 1 
ATOM   7700  C CD2 . HIS C 1 76  ? 27.929  66.832  78.764  1.00 53.94  ? 76  HIS C CD2 1 
ATOM   7701  C CE1 . HIS C 1 76  ? 29.650  65.799  79.629  1.00 55.19  ? 76  HIS C CE1 1 
ATOM   7702  N NE2 . HIS C 1 76  ? 28.993  66.944  79.633  1.00 52.09  ? 76  HIS C NE2 1 
ATOM   7703  N N   . LYS C 1 77  ? 23.680  65.016  75.688  1.00 45.63  ? 77  LYS C N   1 
ATOM   7704  C CA  . LYS C 1 77  ? 22.907  64.556  74.544  1.00 42.93  ? 77  LYS C CA  1 
ATOM   7705  C C   . LYS C 1 77  ? 22.953  65.575  73.407  1.00 36.73  ? 77  LYS C C   1 
ATOM   7706  O O   . LYS C 1 77  ? 22.740  66.754  73.639  1.00 37.09  ? 77  LYS C O   1 
ATOM   7707  C CB  . LYS C 1 77  ? 21.447  64.352  74.973  1.00 46.98  ? 77  LYS C CB  1 
ATOM   7708  C CG  . LYS C 1 77  ? 20.580  63.452  74.078  1.00 45.04  ? 77  LYS C CG  1 
ATOM   7709  C CD  . LYS C 1 77  ? 19.104  63.546  74.431  1.00 37.58  ? 77  LYS C CD  1 
ATOM   7710  C CE  . LYS C 1 77  ? 18.202  62.808  73.474  1.00 37.40  ? 77  LYS C CE  1 
ATOM   7711  N NZ  . LYS C 1 77  ? 18.005  61.358  73.612  1.00 33.14  ? 77  LYS C NZ  1 
ATOM   7712  N N   . LEU C 1 78  ? 23.219  65.103  72.180  1.00 35.00  ? 78  LEU C N   1 
ATOM   7713  C CA  . LEU C 1 78  ? 23.164  65.952  70.990  1.00 34.84  ? 78  LEU C CA  1 
ATOM   7714  C C   . LEU C 1 78  ? 21.705  66.219  70.637  1.00 31.52  ? 78  LEU C C   1 
ATOM   7715  O O   . LEU C 1 78  ? 20.861  65.351  70.842  1.00 34.31  ? 78  LEU C O   1 
ATOM   7716  C CB  . LEU C 1 78  ? 23.896  65.356  69.791  1.00 35.47  ? 78  LEU C CB  1 
ATOM   7717  C CG  . LEU C 1 78  ? 25.423  65.293  69.902  1.00 38.13  ? 78  LEU C CG  1 
ATOM   7718  C CD1 . LEU C 1 78  ? 26.019  64.406  68.835  1.00 38.01  ? 78  LEU C CD1 1 
ATOM   7719  C CD2 . LEU C 1 78  ? 26.033  66.683  69.837  1.00 41.12  ? 78  LEU C CD2 1 
ATOM   7720  N N   . PRO C 1 79  ? 21.365  67.433  70.147  1.00 27.50  ? 79  PRO C N   1 
ATOM   7721  C CA  . PRO C 1 79  ? 19.991  67.752  69.749  1.00 27.76  ? 79  PRO C CA  1 
ATOM   7722  C C   . PRO C 1 79  ? 19.304  66.738  68.835  1.00 28.34  ? 79  PRO C C   1 
ATOM   7723  O O   . PRO C 1 79  ? 19.952  66.169  67.966  1.00 29.44  ? 79  PRO C O   1 
ATOM   7724  C CB  . PRO C 1 79  ? 20.163  69.118  69.081  1.00 26.94  ? 79  PRO C CB  1 
ATOM   7725  C CG  . PRO C 1 79  ? 21.320  69.749  69.850  1.00 27.07  ? 79  PRO C CG  1 
ATOM   7726  C CD  . PRO C 1 79  ? 22.280  68.586  70.029  1.00 27.71  ? 79  PRO C CD  1 
ATOM   7727  N N   . THR C 1 80  ? 18.003  66.502  69.085  1.00 30.04  ? 80  THR C N   1 
ATOM   7728  C CA  . THR C 1 80  ? 17.205  65.521  68.357  1.00 32.54  ? 80  THR C CA  1 
ATOM   7729  C C   . THR C 1 80  ? 16.300  66.241  67.348  1.00 32.84  ? 80  THR C C   1 
ATOM   7730  O O   . THR C 1 80  ? 16.270  67.481  67.264  1.00 25.09  ? 80  THR C O   1 
ATOM   7731  C CB  . THR C 1 80  ? 16.347  64.689  69.324  1.00 30.66  ? 80  THR C CB  1 
ATOM   7732  O OG1 . THR C 1 80  ? 15.528  65.610  70.029  1.00 30.00  ? 80  THR C OG1 1 
ATOM   7733  C CG2 . THR C 1 80  ? 17.126  63.891  70.351  1.00 30.11  ? 80  THR C CG2 1 
ATOM   7734  N N   . ALA C 1 81  ? 15.518  65.438  66.609  1.00 32.75  ? 81  ALA C N   1 
ATOM   7735  C CA  . ALA C 1 81  ? 14.404  66.006  65.859  1.00 35.69  ? 81  ALA C CA  1 
ATOM   7736  C C   . ALA C 1 81  ? 13.325  66.383  66.868  1.00 36.69  ? 81  ALA C C   1 
ATOM   7737  O O   . ALA C 1 81  ? 13.294  65.804  67.957  1.00 36.72  ? 81  ALA C O   1 
ATOM   7738  C CB  . ALA C 1 81  ? 13.904  65.041  64.805  1.00 34.45  ? 81  ALA C CB  1 
ATOM   7739  N N   . GLU C 1 82  ? 12.444  67.336  66.516  1.00 37.21  ? 82  GLU C N   1 
ATOM   7740  C CA  . GLU C 1 82  ? 11.295  67.623  67.364  1.00 40.18  ? 82  GLU C CA  1 
ATOM   7741  C C   . GLU C 1 82  ? 10.515  66.337  67.667  1.00 32.70  ? 82  GLU C C   1 
ATOM   7742  O O   . GLU C 1 82  ? 10.041  65.666  66.761  1.00 28.21  ? 82  GLU C O   1 
ATOM   7743  C CB  . GLU C 1 82  ? 10.353  68.661  66.764  1.00 46.23  ? 82  GLU C CB  1 
ATOM   7744  C CG  . GLU C 1 82  ? 9.427   69.249  67.825  1.00 55.52  ? 82  GLU C CG  1 
ATOM   7745  C CD  . GLU C 1 82  ? 9.057   70.686  67.528  1.00 71.67  ? 82  GLU C CD  1 
ATOM   7746  O OE1 . GLU C 1 82  ? 9.364   71.543  68.382  1.00 76.23  ? 82  GLU C OE1 1 
ATOM   7747  O OE2 . GLU C 1 82  ? 8.488   70.950  66.439  1.00 80.78  ? 82  GLU C OE2 1 
ATOM   7748  N N   . GLY C 1 83  ? 10.421  65.974  68.953  1.00 31.47  ? 83  GLY C N   1 
ATOM   7749  C CA  . GLY C 1 83  ? 9.676   64.795  69.381  1.00 30.50  ? 83  GLY C CA  1 
ATOM   7750  C C   . GLY C 1 83  ? 10.484  63.506  69.230  1.00 33.06  ? 83  GLY C C   1 
ATOM   7751  O O   . GLY C 1 83  ? 9.943   62.410  69.334  1.00 32.25  ? 83  GLY C O   1 
ATOM   7752  N N   . GLY C 1 84  ? 11.801  63.640  69.034  1.00 35.55  ? 84  GLY C N   1 
ATOM   7753  C CA  . GLY C 1 84  ? 12.660  62.489  68.791  1.00 37.54  ? 84  GLY C CA  1 
ATOM   7754  C C   . GLY C 1 84  ? 13.556  62.168  69.984  1.00 36.13  ? 84  GLY C C   1 
ATOM   7755  O O   . GLY C 1 84  ? 13.674  62.958  70.921  1.00 38.15  ? 84  GLY C O   1 
ATOM   7756  N N   . PHE C 1 85  ? 14.183  60.991  69.903  1.00 38.91  ? 85  PHE C N   1 
ATOM   7757  C CA  . PHE C 1 85  ? 15.122  60.499  70.902  1.00 40.78  ? 85  PHE C CA  1 
ATOM   7758  C C   . PHE C 1 85  ? 16.557  60.478  70.343  1.00 37.98  ? 85  PHE C C   1 
ATOM   7759  O O   . PHE C 1 85  ? 17.506  60.908  71.005  1.00 34.04  ? 85  PHE C O   1 
ATOM   7760  C CB  . PHE C 1 85  ? 14.646  59.116  71.365  1.00 43.04  ? 85  PHE C CB  1 
ATOM   7761  C CG  . PHE C 1 85  ? 15.560  58.611  72.473  1.00 56.43  ? 85  PHE C CG  1 
ATOM   7762  C CD1 . PHE C 1 85  ? 15.436  59.107  73.771  1.00 52.96  ? 85  PHE C CD1 1 
ATOM   7763  C CD2 . PHE C 1 85  ? 16.596  57.728  72.189  1.00 55.81  ? 85  PHE C CD2 1 
ATOM   7764  C CE1 . PHE C 1 85  ? 16.291  58.690  74.769  1.00 51.57  ? 85  PHE C CE1 1 
ATOM   7765  C CE2 . PHE C 1 85  ? 17.449  57.314  73.190  1.00 54.55  ? 85  PHE C CE2 1 
ATOM   7766  C CZ  . PHE C 1 85  ? 17.284  57.782  74.478  1.00 60.35  ? 85  PHE C CZ  1 
ATOM   7767  N N   . GLU C 1 86  ? 16.716  59.976  69.110  1.00 35.47  ? 86  GLU C N   1 
ATOM   7768  C CA  . GLU C 1 86  ? 18.037  59.691  68.579  1.00 31.22  ? 86  GLU C CA  1 
ATOM   7769  C C   . GLU C 1 86  ? 18.734  60.987  68.197  1.00 28.32  ? 86  GLU C C   1 
ATOM   7770  O O   . GLU C 1 86  ? 18.101  61.945  67.768  1.00 27.10  ? 86  GLU C O   1 
ATOM   7771  C CB  . GLU C 1 86  ? 17.896  58.696  67.441  1.00 29.69  ? 86  GLU C CB  1 
ATOM   7772  C CG  . GLU C 1 86  ? 17.345  57.365  67.938  1.00 29.98  ? 86  GLU C CG  1 
ATOM   7773  C CD  . GLU C 1 86  ? 18.213  56.628  68.954  1.00 31.24  ? 86  GLU C CD  1 
ATOM   7774  O OE1 . GLU C 1 86  ? 17.677  55.646  69.528  1.00 30.68  ? 86  GLU C OE1 1 
ATOM   7775  O OE2 . GLU C 1 86  ? 19.394  57.010  69.188  1.00 29.50  ? 86  GLU C OE2 1 
ATOM   7776  N N   . PRO C 1 87  ? 20.060  61.077  68.410  1.00 25.32  ? 87  PRO C N   1 
ATOM   7777  C CA  . PRO C 1 87  ? 20.798  62.290  68.082  1.00 26.20  ? 87  PRO C CA  1 
ATOM   7778  C C   . PRO C 1 87  ? 20.955  62.425  66.565  1.00 26.93  ? 87  PRO C C   1 
ATOM   7779  O O   . PRO C 1 87  ? 21.211  61.435  65.882  1.00 22.61  ? 87  PRO C O   1 
ATOM   7780  C CB  . PRO C 1 87  ? 22.109  62.049  68.808  1.00 24.43  ? 87  PRO C CB  1 
ATOM   7781  C CG  . PRO C 1 87  ? 22.294  60.562  68.667  1.00 24.35  ? 87  PRO C CG  1 
ATOM   7782  C CD  . PRO C 1 87  ? 20.920  60.014  68.932  1.00 25.52  ? 87  PRO C CD  1 
ATOM   7783  N N   . LEU C 1 88  ? 20.739  63.656  66.090  1.00 25.90  ? 88  LEU C N   1 
ATOM   7784  C CA  . LEU C 1 88  ? 20.859  64.027  64.699  1.00 26.84  ? 88  LEU C CA  1 
ATOM   7785  C C   . LEU C 1 88  ? 22.328  64.049  64.323  1.00 30.49  ? 88  LEU C C   1 
ATOM   7786  O O   . LEU C 1 88  ? 23.157  64.691  64.992  1.00 32.92  ? 88  LEU C O   1 
ATOM   7787  C CB  . LEU C 1 88  ? 20.227  65.396  64.418  1.00 26.65  ? 88  LEU C CB  1 
ATOM   7788  C CG  . LEU C 1 88  ? 18.697  65.470  64.585  1.00 25.82  ? 88  LEU C CG  1 
ATOM   7789  C CD1 . LEU C 1 88  ? 18.114  66.790  64.135  1.00 25.35  ? 88  LEU C CD1 1 
ATOM   7790  C CD2 . LEU C 1 88  ? 17.976  64.334  63.877  1.00 25.91  ? 88  LEU C CD2 1 
ATOM   7791  N N   . PRO C 1 89  ? 22.663  63.402  63.187  1.00 28.96  ? 89  PRO C N   1 
ATOM   7792  C CA  . PRO C 1 89  ? 24.008  63.508  62.616  1.00 27.83  ? 89  PRO C CA  1 
ATOM   7793  C C   . PRO C 1 89  ? 24.470  64.942  62.398  1.00 27.48  ? 89  PRO C C   1 
ATOM   7794  O O   . PRO C 1 89  ? 25.659  65.215  62.523  1.00 30.34  ? 89  PRO C O   1 
ATOM   7795  C CB  . PRO C 1 89  ? 23.918  62.721  61.324  1.00 27.04  ? 89  PRO C CB  1 
ATOM   7796  C CG  . PRO C 1 89  ? 22.428  62.632  61.069  1.00 29.94  ? 89  PRO C CG  1 
ATOM   7797  C CD  . PRO C 1 89  ? 21.777  62.522  62.420  1.00 28.31  ? 89  PRO C CD  1 
ATOM   7798  N N   . GLU C 1 90  ? 23.535  65.845  62.094  1.00 27.65  ? 90  GLU C N   1 
ATOM   7799  C CA  . GLU C 1 90  ? 23.859  67.245  61.855  1.00 27.73  ? 90  GLU C CA  1 
ATOM   7800  C C   . GLU C 1 90  ? 24.664  67.799  63.027  1.00 27.88  ? 90  GLU C C   1 
ATOM   7801  O O   . GLU C 1 90  ? 25.647  68.497  62.801  1.00 26.98  ? 90  GLU C O   1 
ATOM   7802  C CB  . GLU C 1 90  ? 22.661  68.173  61.628  1.00 28.34  ? 90  GLU C CB  1 
ATOM   7803  C CG  . GLU C 1 90  ? 21.863  67.857  60.361  1.00 31.44  ? 90  GLU C CG  1 
ATOM   7804  C CD  . GLU C 1 90  ? 20.733  66.835  60.394  1.00 29.40  ? 90  GLU C CD  1 
ATOM   7805  O OE1 . GLU C 1 90  ? 19.649  67.203  59.884  1.00 27.95  ? 90  GLU C OE1 1 
ATOM   7806  O OE2 . GLU C 1 90  ? 20.932  65.680  60.868  1.00 28.85  ? 90  GLU C OE2 1 
ATOM   7807  N N   . GLY C 1 91  ? 24.253  67.490  64.266  1.00 28.57  ? 91  GLY C N   1 
ATOM   7808  C CA  . GLY C 1 91  ? 24.914  68.017  65.457  1.00 27.94  ? 91  GLY C CA  1 
ATOM   7809  C C   . GLY C 1 91  ? 26.236  67.301  65.742  1.00 28.48  ? 91  GLY C C   1 
ATOM   7810  O O   . GLY C 1 91  ? 27.253  67.930  66.056  1.00 28.42  ? 91  GLY C O   1 
ATOM   7811  N N   . LEU C 1 92  ? 26.229  65.978  65.557  1.00 28.81  ? 92  LEU C N   1 
ATOM   7812  C CA  . LEU C 1 92  ? 27.454  65.203  65.514  1.00 30.32  ? 92  LEU C CA  1 
ATOM   7813  C C   . LEU C 1 92  ? 28.513  65.886  64.649  1.00 31.25  ? 92  LEU C C   1 
ATOM   7814  O O   . LEU C 1 92  ? 29.672  65.970  65.053  1.00 31.70  ? 92  LEU C O   1 
ATOM   7815  C CB  . LEU C 1 92  ? 27.221  63.788  64.996  1.00 32.93  ? 92  LEU C CB  1 
ATOM   7816  C CG  . LEU C 1 92  ? 28.531  63.038  64.731  1.00 36.61  ? 92  LEU C CG  1 
ATOM   7817  C CD1 . LEU C 1 92  ? 29.263  62.899  66.059  1.00 37.35  ? 92  LEU C CD1 1 
ATOM   7818  C CD2 . LEU C 1 92  ? 28.300  61.698  64.112  1.00 39.47  ? 92  LEU C CD2 1 
ATOM   7819  N N   . TRP C 1 93  ? 28.124  66.316  63.442  1.00 28.81  ? 93  TRP C N   1 
ATOM   7820  C CA  . TRP C 1 93  ? 29.059  66.918  62.510  1.00 29.37  ? 93  TRP C CA  1 
ATOM   7821  C C   . TRP C 1 93  ? 29.660  68.206  63.081  1.00 29.57  ? 93  TRP C C   1 
ATOM   7822  O O   . TRP C 1 93  ? 30.884  68.392  63.031  1.00 27.67  ? 93  TRP C O   1 
ATOM   7823  C CB  . TRP C 1 93  ? 28.352  67.179  61.173  1.00 32.55  ? 93  TRP C CB  1 
ATOM   7824  C CG  . TRP C 1 93  ? 29.263  67.412  59.998  1.00 31.26  ? 93  TRP C CG  1 
ATOM   7825  C CD1 . TRP C 1 93  ? 30.257  66.604  59.541  1.00 30.68  ? 93  TRP C CD1 1 
ATOM   7826  C CD2 . TRP C 1 93  ? 29.243  68.567  59.138  1.00 31.65  ? 93  TRP C CD2 1 
ATOM   7827  N NE1 . TRP C 1 93  ? 30.853  67.176  58.452  1.00 33.31  ? 93  TRP C NE1 1 
ATOM   7828  C CE2 . TRP C 1 93  ? 30.251  68.372  58.173  1.00 32.35  ? 93  TRP C CE2 1 
ATOM   7829  C CE3 . TRP C 1 93  ? 28.469  69.731  59.095  1.00 32.36  ? 93  TRP C CE3 1 
ATOM   7830  C CZ2 . TRP C 1 93  ? 30.517  69.306  57.177  1.00 31.95  ? 93  TRP C CZ2 1 
ATOM   7831  C CZ3 . TRP C 1 93  ? 28.732  70.658  58.113  1.00 35.79  ? 93  TRP C CZ3 1 
ATOM   7832  C CH2 . TRP C 1 93  ? 29.740  70.443  57.165  1.00 36.38  ? 93  TRP C CH2 1 
ATOM   7833  N N   . TYR C 1 94  ? 28.805  69.083  63.633  1.00 29.03  ? 94  TYR C N   1 
ATOM   7834  C CA  . TYR C 1 94  ? 29.254  70.275  64.354  1.00 29.67  ? 94  TYR C CA  1 
ATOM   7835  C C   . TYR C 1 94  ? 30.337  69.924  65.378  1.00 27.81  ? 94  TYR C C   1 
ATOM   7836  O O   . TYR C 1 94  ? 31.306  70.652  65.500  1.00 28.20  ? 94  TYR C O   1 
ATOM   7837  C CB  . TYR C 1 94  ? 28.132  70.973  65.128  1.00 28.83  ? 94  TYR C CB  1 
ATOM   7838  C CG  . TYR C 1 94  ? 28.460  72.358  65.682  1.00 29.57  ? 94  TYR C CG  1 
ATOM   7839  C CD1 . TYR C 1 94  ? 29.090  72.523  66.911  1.00 32.36  ? 94  TYR C CD1 1 
ATOM   7840  C CD2 . TYR C 1 94  ? 28.100  73.509  64.989  1.00 28.70  ? 94  TYR C CD2 1 
ATOM   7841  C CE1 . TYR C 1 94  ? 29.381  73.783  67.416  1.00 32.76  ? 94  TYR C CE1 1 
ATOM   7842  C CE2 . TYR C 1 94  ? 28.391  74.770  65.478  1.00 30.30  ? 94  TYR C CE2 1 
ATOM   7843  C CZ  . TYR C 1 94  ? 29.026  74.920  66.703  1.00 33.89  ? 94  TYR C CZ  1 
ATOM   7844  O OH  . TYR C 1 94  ? 29.319  76.192  67.175  1.00 32.95  ? 94  TYR C OH  1 
ATOM   7845  N N   . LEU C 1 95  ? 30.180  68.789  66.070  1.00 27.01  ? 95  LEU C N   1 
ATOM   7846  C CA  . LEU C 1 95  ? 31.100  68.381  67.114  1.00 29.39  ? 95  LEU C CA  1 
ATOM   7847  C C   . LEU C 1 95  ? 32.452  67.972  66.532  1.00 30.97  ? 95  LEU C C   1 
ATOM   7848  O O   . LEU C 1 95  ? 33.499  68.406  67.039  1.00 28.43  ? 95  LEU C O   1 
ATOM   7849  C CB  . LEU C 1 95  ? 30.489  67.255  67.939  1.00 29.37  ? 95  LEU C CB  1 
ATOM   7850  C CG  . LEU C 1 95  ? 31.424  66.579  68.943  1.00 31.74  ? 95  LEU C CG  1 
ATOM   7851  C CD1 . LEU C 1 95  ? 31.792  67.607  70.004  1.00 34.32  ? 95  LEU C CD1 1 
ATOM   7852  C CD2 . LEU C 1 95  ? 30.820  65.306  69.528  1.00 31.41  ? 95  LEU C CD2 1 
ATOM   7853  N N   . LEU C 1 96  ? 32.419  67.133  65.484  1.00 30.32  ? 96  LEU C N   1 
ATOM   7854  C CA  . LEU C 1 96  ? 33.637  66.674  64.835  1.00 29.06  ? 96  LEU C CA  1 
ATOM   7855  C C   . LEU C 1 96  ? 34.451  67.862  64.338  1.00 30.92  ? 96  LEU C C   1 
ATOM   7856  O O   . LEU C 1 96  ? 35.676  67.837  64.412  1.00 34.59  ? 96  LEU C O   1 
ATOM   7857  C CB  . LEU C 1 96  ? 33.351  65.743  63.668  1.00 27.81  ? 96  LEU C CB  1 
ATOM   7858  C CG  . LEU C 1 96  ? 32.568  64.472  63.973  1.00 27.72  ? 96  LEU C CG  1 
ATOM   7859  C CD1 . LEU C 1 96  ? 32.642  63.600  62.737  1.00 27.49  ? 96  LEU C CD1 1 
ATOM   7860  C CD2 . LEU C 1 96  ? 33.116  63.760  65.191  1.00 29.55  ? 96  LEU C CD2 1 
ATOM   7861  N N   . LEU C 1 97  ? 33.768  68.886  63.822  1.00 29.12  ? 97  LEU C N   1 
ATOM   7862  C CA  . LEU C 1 97  ? 34.461  70.043  63.290  1.00 32.21  ? 97  LEU C CA  1 
ATOM   7863  C C   . LEU C 1 97  ? 34.982  70.974  64.391  1.00 35.32  ? 97  LEU C C   1 
ATOM   7864  O O   . LEU C 1 97  ? 36.051  71.561  64.227  1.00 37.39  ? 97  LEU C O   1 
ATOM   7865  C CB  . LEU C 1 97  ? 33.567  70.818  62.323  1.00 31.64  ? 97  LEU C CB  1 
ATOM   7866  C CG  . LEU C 1 97  ? 33.466  70.244  60.911  1.00 32.93  ? 97  LEU C CG  1 
ATOM   7867  C CD1 . LEU C 1 97  ? 32.294  70.860  60.173  1.00 30.70  ? 97  LEU C CD1 1 
ATOM   7868  C CD2 . LEU C 1 97  ? 34.760  70.505  60.157  1.00 35.46  ? 97  LEU C CD2 1 
ATOM   7869  N N   . THR C 1 98  ? 34.205  71.233  65.448  1.00 34.64  ? 98  THR C N   1 
ATOM   7870  C CA  . THR C 1 98  ? 34.613  72.295  66.359  1.00 35.55  ? 98  THR C CA  1 
ATOM   7871  C C   . THR C 1 98  ? 35.306  71.745  67.604  1.00 33.13  ? 98  THR C C   1 
ATOM   7872  O O   . THR C 1 98  ? 35.901  72.528  68.343  1.00 35.62  ? 98  THR C O   1 
ATOM   7873  C CB  . THR C 1 98  ? 33.434  73.175  66.769  1.00 35.24  ? 98  THR C CB  1 
ATOM   7874  O OG1 . THR C 1 98  ? 32.589  72.290  67.478  1.00 28.48  ? 98  THR C OG1 1 
ATOM   7875  C CG2 . THR C 1 98  ? 32.741  73.807  65.583  1.00 38.71  ? 98  THR C CG2 1 
ATOM   7876  N N   . GLY C 1 99  ? 35.181  70.434  67.844  1.00 31.98  ? 99  GLY C N   1 
ATOM   7877  C CA  . GLY C 1 99  ? 35.417  69.851  69.156  1.00 33.55  ? 99  GLY C CA  1 
ATOM   7878  C C   . GLY C 1 99  ? 34.452  70.331  70.255  1.00 32.35  ? 99  GLY C C   1 
ATOM   7879  O O   . GLY C 1 99  ? 34.670  69.995  71.403  1.00 32.48  ? 99  GLY C O   1 
ATOM   7880  N N   . GLU C 1 100 ? 33.379  71.065  69.913  1.00 33.37  ? 100 GLU C N   1 
ATOM   7881  C CA  . GLU C 1 100 ? 32.445  71.623  70.878  1.00 33.33  ? 100 GLU C CA  1 
ATOM   7882  C C   . GLU C 1 100 ? 31.039  71.062  70.660  1.00 37.22  ? 100 GLU C C   1 
ATOM   7883  O O   . GLU C 1 100 ? 30.696  70.659  69.546  1.00 38.23  ? 100 GLU C O   1 
ATOM   7884  C CB  . GLU C 1 100 ? 32.453  73.148  70.809  1.00 33.58  ? 100 GLU C CB  1 
ATOM   7885  C CG  . GLU C 1 100 ? 33.782  73.747  71.277  1.00 32.38  ? 100 GLU C CG  1 
ATOM   7886  C CD  . GLU C 1 100 ? 33.910  75.215  70.914  1.00 34.78  ? 100 GLU C CD  1 
ATOM   7887  O OE1 . GLU C 1 100 ? 34.972  75.782  71.225  1.00 41.51  ? 100 GLU C OE1 1 
ATOM   7888  O OE2 . GLU C 1 100 ? 32.989  75.796  70.300  1.00 31.27  ? 100 GLU C OE2 1 
ATOM   7889  N N   . LEU C 1 101 ? 30.246  70.999  71.757  1.00 36.93  ? 101 LEU C N   1 
ATOM   7890  C CA  . LEU C 1 101 ? 28.866  70.543  71.703  1.00 33.14  ? 101 LEU C CA  1 
ATOM   7891  C C   . LEU C 1 101 ? 27.995  71.654  71.135  1.00 33.29  ? 101 LEU C C   1 
ATOM   7892  O O   . LEU C 1 101 ? 28.133  72.820  71.500  1.00 31.07  ? 101 LEU C O   1 
ATOM   7893  C CB  . LEU C 1 101 ? 28.325  70.100  73.046  1.00 31.94  ? 101 LEU C CB  1 
ATOM   7894  C CG  . LEU C 1 101 ? 28.979  68.845  73.614  1.00 35.17  ? 101 LEU C CG  1 
ATOM   7895  C CD1 . LEU C 1 101 ? 28.672  68.854  75.116  1.00 38.41  ? 101 LEU C CD1 1 
ATOM   7896  C CD2 . LEU C 1 101 ? 28.531  67.543  72.955  1.00 31.90  ? 101 LEU C CD2 1 
ATOM   7897  N N   . PRO C 1 102 ? 27.103  71.309  70.182  1.00 33.32  ? 102 PRO C N   1 
ATOM   7898  C CA  . PRO C 1 102 ? 26.260  72.299  69.522  1.00 35.61  ? 102 PRO C CA  1 
ATOM   7899  C C   . PRO C 1 102 ? 25.009  72.524  70.356  1.00 34.46  ? 102 PRO C C   1 
ATOM   7900  O O   . PRO C 1 102 ? 24.533  71.570  70.967  1.00 32.75  ? 102 PRO C O   1 
ATOM   7901  C CB  . PRO C 1 102 ? 25.960  71.603  68.181  1.00 32.46  ? 102 PRO C CB  1 
ATOM   7902  C CG  . PRO C 1 102 ? 25.812  70.140  68.578  1.00 34.88  ? 102 PRO C CG  1 
ATOM   7903  C CD  . PRO C 1 102 ? 26.865  69.942  69.676  1.00 34.89  ? 102 PRO C CD  1 
ATOM   7904  N N   . THR C 1 103 ? 24.491  73.761  70.306  1.00 34.14  ? 103 THR C N   1 
ATOM   7905  C CA  . THR C 1 103 ? 23.167  74.100  70.804  1.00 33.58  ? 103 THR C CA  1 
ATOM   7906  C C   . THR C 1 103 ? 22.107  73.605  69.820  1.00 37.63  ? 103 THR C C   1 
ATOM   7907  O O   . THR C 1 103 ? 22.418  73.081  68.749  1.00 35.65  ? 103 THR C O   1 
ATOM   7908  C CB  . THR C 1 103 ? 23.019  75.613  71.033  1.00 36.76  ? 103 THR C CB  1 
ATOM   7909  O OG1 . THR C 1 103 ? 23.100  76.269  69.764  1.00 37.68  ? 103 THR C OG1 1 
ATOM   7910  C CG2 . THR C 1 103 ? 24.027  76.175  72.028  1.00 33.85  ? 103 THR C CG2 1 
ATOM   7911  N N   . GLU C 1 104 ? 20.841  73.786  70.230  1.00 38.84  ? 104 GLU C N   1 
ATOM   7912  C CA  . GLU C 1 104 ? 19.667  73.437  69.455  1.00 35.99  ? 104 GLU C CA  1 
ATOM   7913  C C   . GLU C 1 104 ? 19.664  74.211  68.139  1.00 36.97  ? 104 GLU C C   1 
ATOM   7914  O O   . GLU C 1 104 ? 19.401  73.639  67.088  1.00 35.36  ? 104 GLU C O   1 
ATOM   7915  C CB  . GLU C 1 104 ? 18.425  73.795  70.275  1.00 36.51  ? 104 GLU C CB  1 
ATOM   7916  C CG  . GLU C 1 104 ? 18.174  72.842  71.439  1.00 36.52  ? 104 GLU C CG  1 
ATOM   7917  C CD  . GLU C 1 104 ? 17.674  71.489  70.977  1.00 38.58  ? 104 GLU C CD  1 
ATOM   7918  O OE1 . GLU C 1 104 ? 17.691  70.503  71.747  1.00 37.06  ? 104 GLU C OE1 1 
ATOM   7919  O OE2 . GLU C 1 104 ? 17.243  71.440  69.809  1.00 41.72  ? 104 GLU C OE2 1 
ATOM   7920  N N   . GLU C 1 105 ? 19.943  75.514  68.243  1.00 37.06  ? 105 GLU C N   1 
ATOM   7921  C CA  . GLU C 1 105 ? 19.976  76.435  67.123  1.00 38.88  ? 105 GLU C CA  1 
ATOM   7922  C C   . GLU C 1 105 ? 21.114  76.069  66.183  1.00 38.88  ? 105 GLU C C   1 
ATOM   7923  O O   . GLU C 1 105 ? 20.944  76.172  64.977  1.00 37.09  ? 105 GLU C O   1 
ATOM   7924  C CB  . GLU C 1 105 ? 20.291  77.849  67.621  1.00 41.92  ? 105 GLU C CB  1 
ATOM   7925  C CG  . GLU C 1 105 ? 19.546  78.987  66.919  1.00 47.40  ? 105 GLU C CG  1 
ATOM   7926  C CD  . GLU C 1 105 ? 18.365  78.616  66.041  1.00 50.36  ? 105 GLU C CD  1 
ATOM   7927  O OE1 . GLU C 1 105 ? 17.367  78.041  66.555  1.00 48.32  ? 105 GLU C OE1 1 
ATOM   7928  O OE2 . GLU C 1 105 ? 18.467  78.969  64.844  1.00 48.94  ? 105 GLU C OE2 1 
ATOM   7929  N N   . ASP C 1 106 ? 22.265  75.678  66.756  1.00 37.06  ? 106 ASP C N   1 
ATOM   7930  C CA  . ASP C 1 106 ? 23.446  75.342  65.974  1.00 37.44  ? 106 ASP C CA  1 
ATOM   7931  C C   . ASP C 1 106 ? 23.065  74.255  64.984  1.00 37.28  ? 106 ASP C C   1 
ATOM   7932  O O   . ASP C 1 106 ? 23.396  74.372  63.801  1.00 36.37  ? 106 ASP C O   1 
ATOM   7933  C CB  . ASP C 1 106 ? 24.643  74.967  66.833  1.00 35.93  ? 106 ASP C CB  1 
ATOM   7934  C CG  . ASP C 1 106 ? 25.289  76.111  67.607  1.00 37.50  ? 106 ASP C CG  1 
ATOM   7935  O OD1 . ASP C 1 106 ? 25.192  77.289  67.175  1.00 36.29  ? 106 ASP C OD1 1 
ATOM   7936  O OD2 . ASP C 1 106 ? 25.845  75.820  68.674  1.00 40.52  ? 106 ASP C OD2 1 
ATOM   7937  N N   . VAL C 1 107 ? 22.292  73.269  65.468  1.00 34.43  ? 107 VAL C N   1 
ATOM   7938  C CA  . VAL C 1 107 ? 21.910  72.125  64.649  1.00 36.61  ? 107 VAL C CA  1 
ATOM   7939  C C   . VAL C 1 107 ? 20.822  72.484  63.636  1.00 37.78  ? 107 VAL C C   1 
ATOM   7940  O O   . VAL C 1 107 ? 20.844  71.982  62.511  1.00 39.96  ? 107 VAL C O   1 
ATOM   7941  C CB  . VAL C 1 107 ? 21.482  70.953  65.541  1.00 36.42  ? 107 VAL C CB  1 
ATOM   7942  C CG1 . VAL C 1 107 ? 20.873  69.811  64.741  1.00 36.66  ? 107 VAL C CG1 1 
ATOM   7943  C CG2 . VAL C 1 107 ? 22.661  70.465  66.361  1.00 36.63  ? 107 VAL C CG2 1 
ATOM   7944  N N   . LYS C 1 108 ? 19.878  73.354  64.023  1.00 37.55  ? 108 LYS C N   1 
ATOM   7945  C CA  . LYS C 1 108 ? 18.821  73.760  63.109  1.00 36.30  ? 108 LYS C CA  1 
ATOM   7946  C C   . LYS C 1 108 ? 19.418  74.540  61.937  1.00 34.33  ? 108 LYS C C   1 
ATOM   7947  O O   . LYS C 1 108 ? 18.865  74.475  60.848  1.00 28.73  ? 108 LYS C O   1 
ATOM   7948  C CB  . LYS C 1 108 ? 17.725  74.579  63.796  1.00 39.90  ? 108 LYS C CB  1 
ATOM   7949  C CG  . LYS C 1 108 ? 16.681  73.773  64.572  1.00 41.81  ? 108 LYS C CG  1 
ATOM   7950  C CD  . LYS C 1 108 ? 15.584  74.691  65.108  1.00 46.39  ? 108 LYS C CD  1 
ATOM   7951  C CE  . LYS C 1 108 ? 14.435  74.000  65.771  1.00 51.77  ? 108 LYS C CE  1 
ATOM   7952  N NZ  . LYS C 1 108 ? 14.853  73.414  67.048  1.00 53.96  ? 108 LYS C NZ  1 
ATOM   7953  N N   . GLU C 1 109 ? 20.533  75.263  62.169  1.00 32.46  ? 109 GLU C N   1 
ATOM   7954  C CA  . GLU C 1 109 ? 21.230  75.968  61.109  1.00 36.93  ? 109 GLU C CA  1 
ATOM   7955  C C   . GLU C 1 109 ? 21.848  74.970  60.118  1.00 41.13  ? 109 GLU C C   1 
ATOM   7956  O O   . GLU C 1 109 ? 21.778  75.189  58.916  1.00 40.05  ? 109 GLU C O   1 
ATOM   7957  C CB  . GLU C 1 109 ? 22.343  76.873  61.614  1.00 38.01  ? 109 GLU C CB  1 
ATOM   7958  C CG  . GLU C 1 109 ? 21.846  78.141  62.296  1.00 40.17  ? 109 GLU C CG  1 
ATOM   7959  C CD  . GLU C 1 109 ? 23.013  78.912  62.896  1.00 42.63  ? 109 GLU C CD  1 
ATOM   7960  O OE1 . GLU C 1 109 ? 22.824  79.887  63.651  1.00 44.07  ? 109 GLU C OE1 1 
ATOM   7961  O OE2 . GLU C 1 109 ? 24.151  78.528  62.585  1.00 42.41  ? 109 GLU C OE2 1 
ATOM   7962  N N   . ILE C 1 110 ? 22.427  73.863  60.603  1.00 37.48  ? 110 ILE C N   1 
ATOM   7963  C CA  . ILE C 1 110 ? 23.044  72.889  59.722  1.00 33.74  ? 110 ILE C CA  1 
ATOM   7964  C C   . ILE C 1 110 ? 21.943  72.180  58.929  1.00 34.79  ? 110 ILE C C   1 
ATOM   7965  O O   . ILE C 1 110 ? 22.056  72.012  57.715  1.00 35.93  ? 110 ILE C O   1 
ATOM   7966  C CB  . ILE C 1 110 ? 23.957  71.930  60.517  1.00 33.26  ? 110 ILE C CB  1 
ATOM   7967  C CG1 . ILE C 1 110 ? 25.161  72.680  61.097  1.00 31.88  ? 110 ILE C CG1 1 
ATOM   7968  C CG2 . ILE C 1 110 ? 24.422  70.734  59.671  1.00 34.00  ? 110 ILE C CG2 1 
ATOM   7969  C CD1 . ILE C 1 110 ? 25.942  71.896  62.133  1.00 32.78  ? 110 ILE C CD1 1 
ATOM   7970  N N   . SER C 1 111 ? 20.869  71.777  59.610  1.00 33.64  ? 111 SER C N   1 
ATOM   7971  C CA  . SER C 1 111 ? 19.747  71.118  58.946  1.00 32.68  ? 111 SER C CA  1 
ATOM   7972  C C   . SER C 1 111 ? 19.167  71.983  57.833  1.00 29.81  ? 111 SER C C   1 
ATOM   7973  O O   . SER C 1 111 ? 18.749  71.454  56.818  1.00 31.78  ? 111 SER C O   1 
ATOM   7974  C CB  . SER C 1 111 ? 18.668  70.748  59.925  1.00 30.07  ? 111 SER C CB  1 
ATOM   7975  O OG  . SER C 1 111 ? 19.039  69.556  60.592  1.00 31.85  ? 111 SER C OG  1 
ATOM   7976  N N   . ALA C 1 112 ? 19.097  73.300  58.058  1.00 30.67  ? 112 ALA C N   1 
ATOM   7977  C CA  . ALA C 1 112 ? 18.574  74.232  57.072  1.00 30.09  ? 112 ALA C CA  1 
ATOM   7978  C C   . ALA C 1 112 ? 19.545  74.326  55.898  1.00 34.79  ? 112 ALA C C   1 
ATOM   7979  O O   . ALA C 1 112 ? 19.143  74.341  54.736  1.00 40.67  ? 112 ALA C O   1 
ATOM   7980  C CB  . ALA C 1 112 ? 18.347  75.601  57.677  1.00 27.71  ? 112 ALA C CB  1 
ATOM   7981  N N   . GLU C 1 113 ? 20.837  74.381  56.207  1.00 34.58  ? 113 GLU C N   1 
ATOM   7982  C CA  . GLU C 1 113 ? 21.848  74.498  55.176  1.00 33.80  ? 113 GLU C CA  1 
ATOM   7983  C C   . GLU C 1 113 ? 21.774  73.251  54.289  1.00 35.24  ? 113 GLU C C   1 
ATOM   7984  O O   . GLU C 1 113 ? 21.702  73.381  53.069  1.00 33.18  ? 113 GLU C O   1 
ATOM   7985  C CB  . GLU C 1 113 ? 23.169  74.791  55.879  1.00 34.94  ? 113 GLU C CB  1 
ATOM   7986  C CG  . GLU C 1 113 ? 24.143  75.568  55.015  1.00 37.81  ? 113 GLU C CG  1 
ATOM   7987  C CD  . GLU C 1 113 ? 23.624  76.888  54.519  1.00 37.79  ? 113 GLU C CD  1 
ATOM   7988  O OE1 . GLU C 1 113 ? 23.186  76.943  53.354  1.00 50.65  ? 113 GLU C OE1 1 
ATOM   7989  O OE2 . GLU C 1 113 ? 23.710  77.858  55.267  1.00 36.77  ? 113 GLU C OE2 1 
ATOM   7990  N N   . PHE C 1 114 ? 21.694  72.052  54.890  1.00 36.05  ? 114 PHE C N   1 
ATOM   7991  C CA  . PHE C 1 114 ? 21.589  70.819  54.122  1.00 37.58  ? 114 PHE C CA  1 
ATOM   7992  C C   . PHE C 1 114 ? 20.290  70.783  53.314  1.00 44.41  ? 114 PHE C C   1 
ATOM   7993  O O   . PHE C 1 114 ? 20.297  70.311  52.178  1.00 49.05  ? 114 PHE C O   1 
ATOM   7994  C CB  . PHE C 1 114 ? 21.656  69.559  54.984  1.00 40.09  ? 114 PHE C CB  1 
ATOM   7995  C CG  . PHE C 1 114 ? 22.993  69.257  55.649  1.00 40.42  ? 114 PHE C CG  1 
ATOM   7996  C CD1 . PHE C 1 114 ? 24.154  69.946  55.308  1.00 41.84  ? 114 PHE C CD1 1 
ATOM   7997  C CD2 . PHE C 1 114 ? 23.095  68.225  56.575  1.00 40.85  ? 114 PHE C CD2 1 
ATOM   7998  C CE1 . PHE C 1 114 ? 25.362  69.639  55.926  1.00 42.90  ? 114 PHE C CE1 1 
ATOM   7999  C CE2 . PHE C 1 114 ? 24.306  67.922  57.189  1.00 43.54  ? 114 PHE C CE2 1 
ATOM   8000  C CZ  . PHE C 1 114 ? 25.439  68.631  56.867  1.00 41.53  ? 114 PHE C CZ  1 
ATOM   8001  N N   . THR C 1 115 ? 19.190  71.300  53.883  1.00 41.26  ? 115 THR C N   1 
ATOM   8002  C CA  . THR C 1 115 ? 17.883  71.252  53.238  1.00 42.00  ? 115 THR C CA  1 
ATOM   8003  C C   . THR C 1 115 ? 17.861  72.171  52.007  1.00 35.64  ? 115 THR C C   1 
ATOM   8004  O O   . THR C 1 115 ? 17.474  71.757  50.923  1.00 31.92  ? 115 THR C O   1 
ATOM   8005  C CB  . THR C 1 115 ? 16.798  71.578  54.286  1.00 44.99  ? 115 THR C CB  1 
ATOM   8006  O OG1 . THR C 1 115 ? 16.586  70.388  55.046  1.00 41.11  ? 115 THR C OG1 1 
ATOM   8007  C CG2 . THR C 1 115 ? 15.441  71.930  53.700  1.00 43.32  ? 115 THR C CG2 1 
ATOM   8008  N N   . LYS C 1 116 ? 18.287  73.419  52.154  1.00 34.80  ? 116 LYS C N   1 
ATOM   8009  C CA  . LYS C 1 116 ? 18.333  74.341  51.033  1.00 39.92  ? 116 LYS C CA  1 
ATOM   8010  C C   . LYS C 1 116 ? 19.186  73.798  49.880  1.00 38.56  ? 116 LYS C C   1 
ATOM   8011  O O   . LYS C 1 116 ? 18.828  73.961  48.723  1.00 38.20  ? 116 LYS C O   1 
ATOM   8012  C CB  . LYS C 1 116 ? 18.825  75.704  51.532  1.00 47.60  ? 116 LYS C CB  1 
ATOM   8013  C CG  . LYS C 1 116 ? 19.579  76.579  50.529  1.00 56.70  ? 116 LYS C CG  1 
ATOM   8014  C CD  . LYS C 1 116 ? 20.138  77.834  51.195  1.00 67.21  ? 116 LYS C CD  1 
ATOM   8015  C CE  . LYS C 1 116 ? 21.090  78.606  50.339  1.00 76.05  ? 116 LYS C CE  1 
ATOM   8016  N NZ  . LYS C 1 116 ? 21.198  79.985  50.825  1.00 79.91  ? 116 LYS C NZ  1 
ATOM   8017  N N   . ARG C 1 117 ? 20.335  73.183  50.181  1.00 37.56  ? 117 ARG C N   1 
ATOM   8018  C CA  . ARG C 1 117 ? 21.284  72.775  49.147  1.00 35.52  ? 117 ARG C CA  1 
ATOM   8019  C C   . ARG C 1 117 ? 20.885  71.426  48.550  1.00 33.81  ? 117 ARG C C   1 
ATOM   8020  O O   . ARG C 1 117 ? 21.397  70.998  47.511  1.00 28.99  ? 117 ARG C O   1 
ATOM   8021  C CB  . ARG C 1 117 ? 22.691  72.697  49.747  1.00 33.94  ? 117 ARG C CB  1 
ATOM   8022  C CG  . ARG C 1 117 ? 23.147  74.049  50.265  1.00 33.11  ? 117 ARG C CG  1 
ATOM   8023  C CD  . ARG C 1 117 ? 24.377  73.955  51.127  1.00 31.42  ? 117 ARG C CD  1 
ATOM   8024  N NE  . ARG C 1 117 ? 24.667  75.302  51.622  1.00 29.58  ? 117 ARG C NE  1 
ATOM   8025  C CZ  . ARG C 1 117 ? 25.666  76.062  51.223  1.00 28.80  ? 117 ARG C CZ  1 
ATOM   8026  N NH1 . ARG C 1 117 ? 26.398  75.723  50.189  1.00 28.25  ? 117 ARG C NH1 1 
ATOM   8027  N NH2 . ARG C 1 117 ? 25.890  77.203  51.830  1.00 32.35  ? 117 ARG C NH2 1 
ATOM   8028  N N   . MET C 1 118 ? 19.976  70.749  49.243  1.00 32.36  ? 118 MET C N   1 
ATOM   8029  C CA  . MET C 1 118 ? 19.501  69.460  48.809  1.00 32.91  ? 118 MET C CA  1 
ATOM   8030  C C   . MET C 1 118 ? 18.717  69.655  47.519  1.00 35.00  ? 118 MET C C   1 
ATOM   8031  O O   . MET C 1 118 ? 18.535  68.685  46.803  1.00 37.95  ? 118 MET C O   1 
ATOM   8032  C CB  . MET C 1 118 ? 18.640  68.832  49.905  1.00 32.73  ? 118 MET C CB  1 
ATOM   8033  C CG  . MET C 1 118 ? 18.481  67.359  49.773  1.00 34.20  ? 118 MET C CG  1 
ATOM   8034  S SD  . MET C 1 118 ? 17.682  66.585  51.195  1.00 33.63  ? 118 MET C SD  1 
ATOM   8035  C CE  . MET C 1 118 ? 19.053  66.245  52.304  1.00 37.34  ? 118 MET C CE  1 
ATOM   8036  N N   . GLN C 1 119 ? 18.283  70.901  47.240  1.00 36.80  ? 119 GLN C N   1 
ATOM   8037  C CA  . GLN C 1 119 ? 17.519  71.258  46.041  1.00 40.63  ? 119 GLN C CA  1 
ATOM   8038  C C   . GLN C 1 119 ? 18.433  71.548  44.845  1.00 43.24  ? 119 GLN C C   1 
ATOM   8039  O O   . GLN C 1 119 ? 17.939  71.752  43.737  1.00 43.90  ? 119 GLN C O   1 
ATOM   8040  C CB  . GLN C 1 119 ? 16.758  72.594  46.099  1.00 46.09  ? 119 GLN C CB  1 
ATOM   8041  C CG  . GLN C 1 119 ? 15.725  72.772  47.214  1.00 48.51  ? 119 GLN C CG  1 
ATOM   8042  C CD  . GLN C 1 119 ? 14.675  71.682  47.231  1.00 51.95  ? 119 GLN C CD  1 
ATOM   8043  O OE1 . GLN C 1 119 ? 14.104  71.329  46.189  1.00 50.29  ? 119 GLN C OE1 1 
ATOM   8044  N NE2 . GLN C 1 119 ? 14.436  71.121  48.413  1.00 54.42  ? 119 GLN C NE2 1 
ATOM   8045  N N   . ASN C 1 120 ? 19.754  71.630  45.084  1.00 39.38  ? 120 ASN C N   1 
ATOM   8046  C CA  . ASN C 1 120 ? 20.706  72.122  44.100  1.00 32.83  ? 120 ASN C CA  1 
ATOM   8047  C C   . ASN C 1 120 ? 21.555  71.002  43.526  1.00 28.28  ? 120 ASN C C   1 
ATOM   8048  O O   . ASN C 1 120 ? 22.664  71.259  43.083  1.00 26.28  ? 120 ASN C O   1 
ATOM   8049  C CB  . ASN C 1 120 ? 21.691  73.120  44.684  1.00 34.35  ? 120 ASN C CB  1 
ATOM   8050  C CG  . ASN C 1 120 ? 20.930  74.229  45.343  1.00 37.97  ? 120 ASN C CG  1 
ATOM   8051  O OD1 . ASN C 1 120 ? 19.796  74.505  44.929  1.00 40.53  ? 120 ASN C OD1 1 
ATOM   8052  N ND2 . ASN C 1 120 ? 21.539  74.848  46.341  1.00 37.48  ? 120 ASN C ND2 1 
ATOM   8053  N N   . VAL C 1 121 ? 21.031  69.775  43.488  1.00 26.25  ? 121 VAL C N   1 
ATOM   8054  C CA  . VAL C 1 121 ? 21.739  68.756  42.738  1.00 26.22  ? 121 VAL C CA  1 
ATOM   8055  C C   . VAL C 1 121 ? 21.509  69.051  41.251  1.00 29.00  ? 121 VAL C C   1 
ATOM   8056  O O   . VAL C 1 121 ? 20.370  69.283  40.834  1.00 32.34  ? 121 VAL C O   1 
ATOM   8057  C CB  . VAL C 1 121 ? 21.306  67.349  43.170  1.00 25.27  ? 121 VAL C CB  1 
ATOM   8058  C CG1 . VAL C 1 121 ? 22.044  66.278  42.393  1.00 26.10  ? 121 VAL C CG1 1 
ATOM   8059  C CG2 . VAL C 1 121 ? 21.497  67.128  44.670  1.00 25.17  ? 121 VAL C CG2 1 
ATOM   8060  N N   . PRO C 1 122 ? 22.579  69.148  40.424  1.00 28.59  ? 122 PRO C N   1 
ATOM   8061  C CA  . PRO C 1 122 ? 22.429  69.427  38.994  1.00 27.89  ? 122 PRO C CA  1 
ATOM   8062  C C   . PRO C 1 122 ? 21.717  68.308  38.252  1.00 28.14  ? 122 PRO C C   1 
ATOM   8063  O O   . PRO C 1 122 ? 21.905  67.129  38.548  1.00 26.66  ? 122 PRO C O   1 
ATOM   8064  C CB  . PRO C 1 122 ? 23.853  69.596  38.486  1.00 28.22  ? 122 PRO C CB  1 
ATOM   8065  C CG  . PRO C 1 122 ? 24.662  69.892  39.750  1.00 30.09  ? 122 PRO C CG  1 
ATOM   8066  C CD  . PRO C 1 122 ? 23.993  69.067  40.835  1.00 29.71  ? 122 PRO C CD  1 
ATOM   8067  N N   . GLN C 1 123 ? 20.934  68.706  37.253  1.00 28.27  ? 123 GLN C N   1 
ATOM   8068  C CA  . GLN C 1 123 ? 20.193  67.750  36.452  1.00 28.66  ? 123 GLN C CA  1 
ATOM   8069  C C   . GLN C 1 123 ? 21.162  66.769  35.815  1.00 25.69  ? 123 GLN C C   1 
ATOM   8070  O O   . GLN C 1 123 ? 20.825  65.597  35.701  1.00 25.25  ? 123 GLN C O   1 
ATOM   8071  C CB  . GLN C 1 123 ? 19.387  68.472  35.371  1.00 35.14  ? 123 GLN C CB  1 
ATOM   8072  C CG  . GLN C 1 123 ? 17.943  67.995  35.217  1.00 43.43  ? 123 GLN C CG  1 
ATOM   8073  C CD  . GLN C 1 123 ? 16.980  69.166  35.090  1.00 58.08  ? 123 GLN C CD  1 
ATOM   8074  O OE1 . GLN C 1 123 ? 16.784  69.766  34.019  1.00 62.63  ? 123 GLN C OE1 1 
ATOM   8075  N NE2 . GLN C 1 123 ? 16.380  69.541  36.214  1.00 66.61  ? 123 GLN C NE2 1 
ATOM   8076  N N   . TYR C 1 124 ? 22.343  67.262  35.390  1.00 24.30  ? 124 TYR C N   1 
ATOM   8077  C CA  . TYR C 1 124 ? 23.300  66.446  34.666  1.00 22.49  ? 124 TYR C CA  1 
ATOM   8078  C C   . TYR C 1 124 ? 23.783  65.303  35.551  1.00 22.53  ? 124 TYR C C   1 
ATOM   8079  O O   . TYR C 1 124 ? 24.150  64.272  35.016  1.00 22.19  ? 124 TYR C O   1 
ATOM   8080  C CB  . TYR C 1 124 ? 24.526  67.138  34.049  1.00 23.84  ? 124 TYR C CB  1 
ATOM   8081  C CG  . TYR C 1 124 ? 25.496  67.770  35.031  1.00 22.19  ? 124 TYR C CG  1 
ATOM   8082  C CD1 . TYR C 1 124 ? 26.513  67.036  35.620  1.00 20.33  ? 124 TYR C CD1 1 
ATOM   8083  C CD2 . TYR C 1 124 ? 25.384  69.120  35.362  1.00 23.80  ? 124 TYR C CD2 1 
ATOM   8084  C CE1 . TYR C 1 124 ? 27.369  67.610  36.546  1.00 20.56  ? 124 TYR C CE1 1 
ATOM   8085  C CE2 . TYR C 1 124 ? 26.239  69.709  36.288  1.00 23.13  ? 124 TYR C CE2 1 
ATOM   8086  C CZ  . TYR C 1 124 ? 27.221  68.945  36.897  1.00 21.65  ? 124 TYR C CZ  1 
ATOM   8087  O OH  . TYR C 1 124 ? 28.028  69.577  37.801  1.00 19.73  ? 124 TYR C OH  1 
ATOM   8088  N N   . VAL C 1 125 ? 23.761  65.449  36.888  1.00 23.35  ? 125 VAL C N   1 
ATOM   8089  C CA  . VAL C 1 125 ? 24.146  64.350  37.759  1.00 21.06  ? 125 VAL C CA  1 
ATOM   8090  C C   . VAL C 1 125 ? 23.179  63.190  37.578  1.00 21.84  ? 125 VAL C C   1 
ATOM   8091  O O   . VAL C 1 125 ? 23.586  62.038  37.600  1.00 23.92  ? 125 VAL C O   1 
ATOM   8092  C CB  . VAL C 1 125 ? 24.225  64.726  39.243  1.00 21.43  ? 125 VAL C CB  1 
ATOM   8093  C CG1 . VAL C 1 125 ? 24.313  63.481  40.114  1.00 22.35  ? 125 VAL C CG1 1 
ATOM   8094  C CG2 . VAL C 1 125 ? 25.380  65.675  39.533  1.00 20.13  ? 125 VAL C CG2 1 
ATOM   8095  N N   . PHE C 1 126 ? 21.894  63.489  37.396  1.00 23.54  ? 126 PHE C N   1 
ATOM   8096  C CA  . PHE C 1 126 ? 20.897  62.455  37.155  1.00 24.40  ? 126 PHE C CA  1 
ATOM   8097  C C   . PHE C 1 126 ? 21.067  61.875  35.748  1.00 24.69  ? 126 PHE C C   1 
ATOM   8098  O O   . PHE C 1 126 ? 20.964  60.654  35.556  1.00 23.73  ? 126 PHE C O   1 
ATOM   8099  C CB  . PHE C 1 126 ? 19.478  62.982  37.431  1.00 26.54  ? 126 PHE C CB  1 
ATOM   8100  C CG  . PHE C 1 126 ? 19.254  63.546  38.833  1.00 27.51  ? 126 PHE C CG  1 
ATOM   8101  C CD1 . PHE C 1 126 ? 19.259  62.717  39.948  1.00 27.23  ? 126 PHE C CD1 1 
ATOM   8102  C CD2 . PHE C 1 126 ? 19.080  64.908  39.035  1.00 27.27  ? 126 PHE C CD2 1 
ATOM   8103  C CE1 . PHE C 1 126 ? 19.097  63.245  41.222  1.00 30.98  ? 126 PHE C CE1 1 
ATOM   8104  C CE2 . PHE C 1 126 ? 18.912  65.428  40.311  1.00 29.35  ? 126 PHE C CE2 1 
ATOM   8105  C CZ  . PHE C 1 126 ? 18.915  64.599  41.405  1.00 29.31  ? 126 PHE C CZ  1 
ATOM   8106  N N   . ASP C 1 127 ? 21.329  62.742  34.760  1.00 23.73  ? 127 ASP C N   1 
ATOM   8107  C CA  . ASP C 1 127 ? 21.607  62.264  33.418  1.00 23.23  ? 127 ASP C CA  1 
ATOM   8108  C C   . ASP C 1 127 ? 22.713  61.220  33.468  1.00 24.11  ? 127 ASP C C   1 
ATOM   8109  O O   . ASP C 1 127 ? 22.637  60.211  32.768  1.00 23.54  ? 127 ASP C O   1 
ATOM   8110  C CB  . ASP C 1 127 ? 22.016  63.375  32.466  1.00 25.09  ? 127 ASP C CB  1 
ATOM   8111  C CG  . ASP C 1 127 ? 20.943  64.402  32.132  1.00 25.32  ? 127 ASP C CG  1 
ATOM   8112  O OD1 . ASP C 1 127 ? 19.765  64.127  32.396  1.00 23.41  ? 127 ASP C OD1 1 
ATOM   8113  O OD2 . ASP C 1 127 ? 21.311  65.499  31.661  1.00 29.95  ? 127 ASP C OD2 1 
ATOM   8114  N N   . VAL C 1 128 ? 23.753  61.485  34.278  1.00 26.93  ? 128 VAL C N   1 
ATOM   8115  C CA  . VAL C 1 128 ? 24.898  60.587  34.390  1.00 25.54  ? 128 VAL C CA  1 
ATOM   8116  C C   . VAL C 1 128 ? 24.456  59.283  35.043  1.00 26.44  ? 128 VAL C C   1 
ATOM   8117  O O   . VAL C 1 128 ? 24.790  58.204  34.550  1.00 29.75  ? 128 VAL C O   1 
ATOM   8118  C CB  . VAL C 1 128 ? 26.089  61.216  35.132  1.00 23.49  ? 128 VAL C CB  1 
ATOM   8119  C CG1 . VAL C 1 128 ? 27.153  60.191  35.486  1.00 23.33  ? 128 VAL C CG1 1 
ATOM   8120  C CG2 . VAL C 1 128 ? 26.694  62.351  34.308  1.00 22.29  ? 128 VAL C CG2 1 
ATOM   8121  N N   . LEU C 1 129 ? 23.686  59.386  36.129  1.00 25.46  ? 129 LEU C N   1 
ATOM   8122  C CA  . LEU C 1 129 ? 23.176  58.206  36.810  1.00 25.44  ? 129 LEU C CA  1 
ATOM   8123  C C   . LEU C 1 129 ? 22.318  57.335  35.896  1.00 25.26  ? 129 LEU C C   1 
ATOM   8124  O O   . LEU C 1 129 ? 22.442  56.119  35.957  1.00 26.63  ? 129 LEU C O   1 
ATOM   8125  C CB  . LEU C 1 129 ? 22.420  58.670  38.049  1.00 27.72  ? 129 LEU C CB  1 
ATOM   8126  C CG  . LEU C 1 129 ? 23.304  59.195  39.186  1.00 29.42  ? 129 LEU C CG  1 
ATOM   8127  C CD1 . LEU C 1 129 ? 22.500  59.937  40.233  1.00 28.77  ? 129 LEU C CD1 1 
ATOM   8128  C CD2 . LEU C 1 129 ? 24.074  58.029  39.811  1.00 29.38  ? 129 LEU C CD2 1 
ATOM   8129  N N   . ARG C 1 130 ? 21.461  57.949  35.065  1.00 27.49  ? 130 ARG C N   1 
ATOM   8130  C CA  . ARG C 1 130 ? 20.608  57.239  34.110  1.00 28.72  ? 130 ARG C CA  1 
ATOM   8131  C C   . ARG C 1 130 ? 21.409  56.597  32.968  1.00 26.26  ? 130 ARG C C   1 
ATOM   8132  O O   . ARG C 1 130 ? 20.965  55.607  32.366  1.00 25.06  ? 130 ARG C O   1 
ATOM   8133  C CB  . ARG C 1 130 ? 19.496  58.110  33.491  1.00 28.51  ? 130 ARG C CB  1 
ATOM   8134  C CG  . ARG C 1 130 ? 18.375  58.459  34.462  1.00 30.31  ? 130 ARG C CG  1 
ATOM   8135  C CD  . ARG C 1 130 ? 17.076  59.025  33.880  1.00 30.52  ? 130 ARG C CD  1 
ATOM   8136  N NE  . ARG C 1 130 ? 16.113  58.032  33.391  1.00 31.78  ? 130 ARG C NE  1 
ATOM   8137  C CZ  . ARG C 1 130 ? 15.430  57.185  34.160  1.00 30.97  ? 130 ARG C CZ  1 
ATOM   8138  N NH1 . ARG C 1 130 ? 14.492  56.389  33.648  1.00 32.84  ? 130 ARG C NH1 1 
ATOM   8139  N NH2 . ARG C 1 130 ? 15.665  57.145  35.458  1.00 27.63  ? 130 ARG C NH2 1 
ATOM   8140  N N   . ALA C 1 131 ? 22.581  57.147  32.650  1.00 26.57  ? 131 ALA C N   1 
ATOM   8141  C CA  . ALA C 1 131 ? 23.403  56.588  31.582  1.00 28.26  ? 131 ALA C CA  1 
ATOM   8142  C C   . ALA C 1 131 ? 23.981  55.224  31.975  1.00 27.35  ? 131 ALA C C   1 
ATOM   8143  O O   . ALA C 1 131 ? 24.236  54.385  31.109  1.00 28.00  ? 131 ALA C O   1 
ATOM   8144  C CB  . ALA C 1 131 ? 24.494  57.555  31.191  1.00 28.98  ? 131 ALA C CB  1 
ATOM   8145  N N   . MET C 1 132 ? 24.155  54.988  33.279  1.00 26.50  ? 132 MET C N   1 
ATOM   8146  C CA  . MET C 1 132 ? 24.739  53.742  33.770  1.00 25.55  ? 132 MET C CA  1 
ATOM   8147  C C   . MET C 1 132 ? 23.704  52.635  33.705  1.00 25.36  ? 132 MET C C   1 
ATOM   8148  O O   . MET C 1 132 ? 22.616  52.767  34.230  1.00 26.54  ? 132 MET C O   1 
ATOM   8149  C CB  . MET C 1 132 ? 25.222  53.852  35.218  1.00 23.71  ? 132 MET C CB  1 
ATOM   8150  C CG  . MET C 1 132 ? 26.182  54.984  35.396  1.00 25.86  ? 132 MET C CG  1 
ATOM   8151  S SD  . MET C 1 132 ? 26.716  55.393  37.065  1.00 28.64  ? 132 MET C SD  1 
ATOM   8152  C CE  . MET C 1 132 ? 28.224  54.406  37.030  1.00 26.96  ? 132 MET C CE  1 
ATOM   8153  N N   . PRO C 1 133 ? 24.026  51.476  33.119  1.00 26.24  ? 133 PRO C N   1 
ATOM   8154  C CA  . PRO C 1 133 ? 23.098  50.361  33.148  1.00 29.15  ? 133 PRO C CA  1 
ATOM   8155  C C   . PRO C 1 133 ? 22.617  50.215  34.583  1.00 30.61  ? 133 PRO C C   1 
ATOM   8156  O O   . PRO C 1 133 ? 23.386  50.457  35.519  1.00 29.95  ? 133 PRO C O   1 
ATOM   8157  C CB  . PRO C 1 133 ? 23.920  49.183  32.670  1.00 27.89  ? 133 PRO C CB  1 
ATOM   8158  C CG  . PRO C 1 133 ? 24.966  49.818  31.821  1.00 29.07  ? 133 PRO C CG  1 
ATOM   8159  C CD  . PRO C 1 133 ? 25.295  51.151  32.472  1.00 28.22  ? 133 PRO C CD  1 
ATOM   8160  N N   . VAL C 1 134 ? 21.356  49.776  34.716  1.00 31.27  ? 134 VAL C N   1 
ATOM   8161  C CA  . VAL C 1 134 ? 20.642  49.784  35.987  1.00 28.41  ? 134 VAL C CA  1 
ATOM   8162  C C   . VAL C 1 134 ? 21.172  48.688  36.901  1.00 24.61  ? 134 VAL C C   1 
ATOM   8163  O O   . VAL C 1 134 ? 21.045  48.777  38.123  1.00 26.54  ? 134 VAL C O   1 
ATOM   8164  C CB  . VAL C 1 134 ? 19.115  49.660  35.795  1.00 27.18  ? 134 VAL C CB  1 
ATOM   8165  C CG1 . VAL C 1 134 ? 18.690  48.363  35.121  1.00 24.30  ? 134 VAL C CG1 1 
ATOM   8166  C CG2 . VAL C 1 134 ? 18.378  49.840  37.118  1.00 28.77  ? 134 VAL C CG2 1 
ATOM   8167  N N   . ASP C 1 135 ? 21.738  47.650  36.298  1.00 22.85  ? 135 ASP C N   1 
ATOM   8168  C CA  . ASP C 1 135 ? 22.333  46.574  37.069  1.00 23.81  ? 135 ASP C CA  1 
ATOM   8169  C C   . ASP C 1 135 ? 23.777  46.895  37.487  1.00 22.82  ? 135 ASP C C   1 
ATOM   8170  O O   . ASP C 1 135 ? 24.432  46.026  38.037  1.00 23.58  ? 135 ASP C O   1 
ATOM   8171  C CB  . ASP C 1 135 ? 22.245  45.263  36.303  1.00 23.43  ? 135 ASP C CB  1 
ATOM   8172  C CG  . ASP C 1 135 ? 23.014  45.276  34.993  1.00 23.59  ? 135 ASP C CG  1 
ATOM   8173  O OD1 . ASP C 1 135 ? 23.458  46.385  34.614  1.00 22.12  ? 135 ASP C OD1 1 
ATOM   8174  O OD2 . ASP C 1 135 ? 23.143  44.192  34.363  1.00 22.22  ? 135 ASP C OD2 1 
ATOM   8175  N N   . THR C 1 136 ? 24.304  48.106  37.236  1.00 23.10  ? 136 THR C N   1 
ATOM   8176  C CA  . THR C 1 136 ? 25.572  48.527  37.829  1.00 22.78  ? 136 THR C CA  1 
ATOM   8177  C C   . THR C 1 136 ? 25.469  48.465  39.361  1.00 26.35  ? 136 THR C C   1 
ATOM   8178  O O   . THR C 1 136 ? 24.422  48.725  39.950  1.00 27.27  ? 136 THR C O   1 
ATOM   8179  C CB  . THR C 1 136 ? 25.912  49.951  37.402  1.00 22.21  ? 136 THR C CB  1 
ATOM   8180  O OG1 . THR C 1 136 ? 26.060  50.023  35.989  1.00 19.60  ? 136 THR C OG1 1 
ATOM   8181  C CG2 . THR C 1 136 ? 27.179  50.445  38.070  1.00 23.58  ? 136 THR C CG2 1 
ATOM   8182  N N   . HIS C 1 137 ? 26.582  48.162  40.031  1.00 26.95  ? 137 HIS C N   1 
ATOM   8183  C CA  . HIS C 1 137 ? 26.582  48.026  41.473  1.00 26.65  ? 137 HIS C CA  1 
ATOM   8184  C C   . HIS C 1 137 ? 26.297  49.393  42.083  1.00 27.57  ? 137 HIS C C   1 
ATOM   8185  O O   . HIS C 1 137 ? 26.704  50.422  41.558  1.00 24.71  ? 137 HIS C O   1 
ATOM   8186  C CB  . HIS C 1 137 ? 27.904  47.419  41.953  1.00 26.78  ? 137 HIS C CB  1 
ATOM   8187  C CG  . HIS C 1 137 ? 27.970  47.108  43.411  1.00 25.79  ? 137 HIS C CG  1 
ATOM   8188  N ND1 . HIS C 1 137 ? 27.888  48.068  44.408  1.00 24.43  ? 137 HIS C ND1 1 
ATOM   8189  C CD2 . HIS C 1 137 ? 28.091  45.916  44.031  1.00 24.54  ? 137 HIS C CD2 1 
ATOM   8190  C CE1 . HIS C 1 137 ? 27.980  47.468  45.585  1.00 22.68  ? 137 HIS C CE1 1 
ATOM   8191  N NE2 . HIS C 1 137 ? 28.091  46.158  45.384  1.00 21.97  ? 137 HIS C NE2 1 
ATOM   8192  N N   . PRO C 1 138 ? 25.516  49.463  43.181  1.00 28.55  ? 138 PRO C N   1 
ATOM   8193  C CA  . PRO C 1 138 ? 25.150  50.761  43.737  1.00 26.35  ? 138 PRO C CA  1 
ATOM   8194  C C   . PRO C 1 138 ? 26.343  51.608  44.177  1.00 23.83  ? 138 PRO C C   1 
ATOM   8195  O O   . PRO C 1 138 ? 26.259  52.835  44.147  1.00 23.27  ? 138 PRO C O   1 
ATOM   8196  C CB  . PRO C 1 138 ? 24.143  50.462  44.867  1.00 27.33  ? 138 PRO C CB  1 
ATOM   8197  C CG  . PRO C 1 138 ? 24.168  48.960  45.048  1.00 28.58  ? 138 PRO C CG  1 
ATOM   8198  C CD  . PRO C 1 138 ? 24.818  48.340  43.813  1.00 28.40  ? 138 PRO C CD  1 
ATOM   8199  N N   . MET C 1 139 ? 27.468  50.990  44.530  1.00 23.42  ? 139 MET C N   1 
ATOM   8200  C CA  . MET C 1 139 ? 28.602  51.769  45.031  1.00 24.86  ? 139 MET C CA  1 
ATOM   8201  C C   . MET C 1 139 ? 29.363  52.428  43.868  1.00 25.66  ? 139 MET C C   1 
ATOM   8202  O O   . MET C 1 139 ? 29.947  53.506  44.014  1.00 28.07  ? 139 MET C O   1 
ATOM   8203  C CB  . MET C 1 139 ? 29.515  50.902  45.907  1.00 23.89  ? 139 MET C CB  1 
ATOM   8204  C CG  . MET C 1 139 ? 28.986  50.685  47.322  1.00 24.09  ? 139 MET C CG  1 
ATOM   8205  S SD  . MET C 1 139 ? 28.920  52.234  48.243  1.00 27.03  ? 139 MET C SD  1 
ATOM   8206  C CE  . MET C 1 139 ? 30.641  52.737  48.254  1.00 28.56  ? 139 MET C CE  1 
ATOM   8207  N N   . THR C 1 140 ? 29.312  51.799  42.683  1.00 26.56  ? 140 THR C N   1 
ATOM   8208  C CA  . THR C 1 140 ? 29.854  52.367  41.452  1.00 23.15  ? 140 THR C CA  1 
ATOM   8209  C C   . THR C 1 140 ? 29.017  53.572  41.042  1.00 21.82  ? 140 THR C C   1 
ATOM   8210  O O   . THR C 1 140 ? 29.559  54.643  40.801  1.00 23.04  ? 140 THR C O   1 
ATOM   8211  C CB  . THR C 1 140 ? 29.851  51.280  40.385  1.00 23.06  ? 140 THR C CB  1 
ATOM   8212  O OG1 . THR C 1 140 ? 30.604  50.217  40.962  1.00 21.94  ? 140 THR C OG1 1 
ATOM   8213  C CG2 . THR C 1 140 ? 30.451  51.754  39.078  1.00 24.39  ? 140 THR C CG2 1 
ATOM   8214  N N   . MET C 1 141 ? 27.692  53.383  41.002  1.00 20.68  ? 141 MET C N   1 
ATOM   8215  C CA  . MET C 1 141 ? 26.763  54.455  40.676  1.00 22.36  ? 141 MET C CA  1 
ATOM   8216  C C   . MET C 1 141 ? 26.910  55.629  41.639  1.00 23.71  ? 141 MET C C   1 
ATOM   8217  O O   . MET C 1 141 ? 26.842  56.781  41.210  1.00 22.90  ? 141 MET C O   1 
ATOM   8218  C CB  . MET C 1 141 ? 25.304  54.018  40.817  1.00 26.41  ? 141 MET C CB  1 
ATOM   8219  C CG  . MET C 1 141 ? 24.790  53.063  39.761  1.00 26.82  ? 141 MET C CG  1 
ATOM   8220  S SD  . MET C 1 141 ? 23.034  52.778  40.022  1.00 25.84  ? 141 MET C SD  1 
ATOM   8221  C CE  . MET C 1 141 ? 22.708  51.550  38.751  1.00 26.58  ? 141 MET C CE  1 
ATOM   8222  N N   . PHE C 1 142 ? 27.078  55.316  42.937  1.00 23.02  ? 142 PHE C N   1 
ATOM   8223  C CA  . PHE C 1 142 ? 27.188  56.330  43.977  1.00 24.18  ? 142 PHE C CA  1 
ATOM   8224  C C   . PHE C 1 142 ? 28.432  57.188  43.750  1.00 23.78  ? 142 PHE C C   1 
ATOM   8225  O O   . PHE C 1 142 ? 28.341  58.418  43.708  1.00 25.17  ? 142 PHE C O   1 
ATOM   8226  C CB  . PHE C 1 142 ? 27.222  55.647  45.354  1.00 25.29  ? 142 PHE C CB  1 
ATOM   8227  C CG  . PHE C 1 142 ? 27.149  56.562  46.572  1.00 24.89  ? 142 PHE C CG  1 
ATOM   8228  C CD1 . PHE C 1 142 ? 26.169  57.534  46.681  1.00 23.31  ? 142 PHE C CD1 1 
ATOM   8229  C CD2 . PHE C 1 142 ? 28.075  56.457  47.606  1.00 24.14  ? 142 PHE C CD2 1 
ATOM   8230  C CE1 . PHE C 1 142 ? 26.096  58.348  47.800  1.00 22.96  ? 142 PHE C CE1 1 
ATOM   8231  C CE2 . PHE C 1 142 ? 27.993  57.284  48.716  1.00 24.75  ? 142 PHE C CE2 1 
ATOM   8232  C CZ  . PHE C 1 142 ? 27.002  58.226  48.809  1.00 23.78  ? 142 PHE C CZ  1 
ATOM   8233  N N   . ALA C 1 143 ? 29.587  56.524  43.607  1.00 22.95  ? 143 ALA C N   1 
ATOM   8234  C CA  . ALA C 1 143 ? 30.849  57.223  43.447  1.00 21.66  ? 143 ALA C CA  1 
ATOM   8235  C C   . ALA C 1 143 ? 30.836  58.004  42.136  1.00 21.59  ? 143 ALA C C   1 
ATOM   8236  O O   . ALA C 1 143 ? 31.246  59.156  42.112  1.00 23.90  ? 143 ALA C O   1 
ATOM   8237  C CB  . ALA C 1 143 ? 31.983  56.236  43.518  1.00 21.70  ? 143 ALA C CB  1 
ATOM   8238  N N   . ALA C 1 144 ? 30.299  57.410  41.068  1.00 20.89  ? 144 ALA C N   1 
ATOM   8239  C CA  . ALA C 1 144 ? 30.264  58.095  39.795  1.00 22.79  ? 144 ALA C CA  1 
ATOM   8240  C C   . ALA C 1 144 ? 29.424  59.376  39.900  1.00 26.63  ? 144 ALA C C   1 
ATOM   8241  O O   . ALA C 1 144 ? 29.853  60.446  39.435  1.00 32.73  ? 144 ALA C O   1 
ATOM   8242  C CB  . ALA C 1 144 ? 29.757  57.162  38.721  1.00 23.99  ? 144 ALA C CB  1 
ATOM   8243  N N   . GLY C 1 145 ? 28.228  59.275  40.504  1.00 22.02  ? 145 GLY C N   1 
ATOM   8244  C CA  . GLY C 1 145 ? 27.373  60.428  40.659  1.00 21.06  ? 145 GLY C CA  1 
ATOM   8245  C C   . GLY C 1 145 ? 28.071  61.518  41.473  1.00 24.24  ? 145 GLY C C   1 
ATOM   8246  O O   . GLY C 1 145 ? 27.975  62.701  41.144  1.00 26.14  ? 145 GLY C O   1 
ATOM   8247  N N   . ILE C 1 146 ? 28.785  61.139  42.540  1.00 24.32  ? 146 ILE C N   1 
ATOM   8248  C CA  . ILE C 1 146 ? 29.518  62.133  43.326  1.00 26.22  ? 146 ILE C CA  1 
ATOM   8249  C C   . ILE C 1 146 ? 30.576  62.821  42.460  1.00 26.94  ? 146 ILE C C   1 
ATOM   8250  O O   . ILE C 1 146 ? 30.721  64.053  42.515  1.00 23.86  ? 146 ILE C O   1 
ATOM   8251  C CB  . ILE C 1 146 ? 30.143  61.524  44.601  1.00 27.49  ? 146 ILE C CB  1 
ATOM   8252  C CG1 . ILE C 1 146 ? 29.064  61.005  45.569  1.00 26.83  ? 146 ILE C CG1 1 
ATOM   8253  C CG2 . ILE C 1 146 ? 31.065  62.539  45.281  1.00 28.81  ? 146 ILE C CG2 1 
ATOM   8254  C CD1 . ILE C 1 146 ? 29.506  59.849  46.446  1.00 26.36  ? 146 ILE C CD1 1 
ATOM   8255  N N   . LEU C 1 147 ? 31.313  62.010  41.674  1.00 26.77  ? 147 LEU C N   1 
ATOM   8256  C CA  . LEU C 1 147 ? 32.404  62.522  40.866  1.00 25.86  ? 147 LEU C CA  1 
ATOM   8257  C C   . LEU C 1 147 ? 31.904  63.534  39.825  1.00 26.63  ? 147 LEU C C   1 
ATOM   8258  O O   . LEU C 1 147 ? 32.506  64.595  39.637  1.00 23.75  ? 147 LEU C O   1 
ATOM   8259  C CB  . LEU C 1 147 ? 33.146  61.355  40.233  1.00 24.96  ? 147 LEU C CB  1 
ATOM   8260  C CG  . LEU C 1 147 ? 34.361  61.742  39.390  1.00 24.15  ? 147 LEU C CG  1 
ATOM   8261  C CD1 . LEU C 1 147 ? 35.371  62.553  40.125  1.00 23.11  ? 147 LEU C CD1 1 
ATOM   8262  C CD2 . LEU C 1 147 ? 35.000  60.498  38.886  1.00 25.65  ? 147 LEU C CD2 1 
ATOM   8263  N N   . ALA C 1 148 ? 30.769  63.246  39.185  1.00 25.86  ? 148 ALA C N   1 
ATOM   8264  C CA  . ALA C 1 148 ? 30.251  64.129  38.149  1.00 23.16  ? 148 ALA C CA  1 
ATOM   8265  C C   . ALA C 1 148 ? 29.978  65.524  38.710  1.00 22.67  ? 148 ALA C C   1 
ATOM   8266  O O   . ALA C 1 148 ? 30.158  66.523  38.005  1.00 21.42  ? 148 ALA C O   1 
ATOM   8267  C CB  . ALA C 1 148 ? 29.018  63.503  37.539  1.00 23.55  ? 148 ALA C CB  1 
ATOM   8268  N N   . MET C 1 149 ? 29.580  65.598  39.999  1.00 23.99  ? 149 MET C N   1 
ATOM   8269  C CA  . MET C 1 149 ? 29.259  66.875  40.653  1.00 22.85  ? 149 MET C CA  1 
ATOM   8270  C C   . MET C 1 149 ? 30.516  67.725  40.865  1.00 22.41  ? 149 MET C C   1 
ATOM   8271  O O   . MET C 1 149 ? 30.439  68.867  41.291  1.00 23.01  ? 149 MET C O   1 
ATOM   8272  C CB  . MET C 1 149 ? 28.534  66.634  41.981  1.00 21.73  ? 149 MET C CB  1 
ATOM   8273  C CG  . MET C 1 149 ? 27.870  67.848  42.580  1.00 22.65  ? 149 MET C CG  1 
ATOM   8274  S SD  . MET C 1 149 ? 26.464  67.484  43.671  1.00 25.32  ? 149 MET C SD  1 
ATOM   8275  C CE  . MET C 1 149 ? 26.119  69.183  44.145  1.00 22.06  ? 149 MET C CE  1 
ATOM   8276  N N   . GLN C 1 150 ? 31.682  67.183  40.516  1.00 24.51  ? 150 GLN C N   1 
ATOM   8277  C CA  . GLN C 1 150 ? 32.956  67.866  40.680  1.00 24.74  ? 150 GLN C CA  1 
ATOM   8278  C C   . GLN C 1 150 ? 33.006  69.168  39.900  1.00 25.62  ? 150 GLN C C   1 
ATOM   8279  O O   . GLN C 1 150 ? 33.781  70.050  40.249  1.00 23.98  ? 150 GLN C O   1 
ATOM   8280  C CB  . GLN C 1 150 ? 34.081  66.951  40.223  1.00 24.22  ? 150 GLN C CB  1 
ATOM   8281  C CG  . GLN C 1 150 ? 35.471  67.511  40.484  1.00 27.78  ? 150 GLN C CG  1 
ATOM   8282  C CD  . GLN C 1 150 ? 35.978  68.503  39.450  1.00 27.57  ? 150 GLN C CD  1 
ATOM   8283  O OE1 . GLN C 1 150 ? 35.672  68.423  38.242  1.00 24.54  ? 150 GLN C OE1 1 
ATOM   8284  N NE2 . GLN C 1 150 ? 36.765  69.449  39.953  1.00 25.66  ? 150 GLN C NE2 1 
ATOM   8285  N N   . ARG C 1 151 ? 32.178  69.282  38.853  1.00 27.71  ? 151 ARG C N   1 
ATOM   8286  C CA  . ARG C 1 151 ? 32.119  70.502  38.059  1.00 28.11  ? 151 ARG C CA  1 
ATOM   8287  C C   . ARG C 1 151 ? 31.658  71.694  38.897  1.00 27.49  ? 151 ARG C C   1 
ATOM   8288  O O   . ARG C 1 151 ? 31.922  72.847  38.558  1.00 26.65  ? 151 ARG C O   1 
ATOM   8289  C CB  . ARG C 1 151 ? 31.120  70.303  36.915  1.00 29.98  ? 151 ARG C CB  1 
ATOM   8290  C CG  . ARG C 1 151 ? 30.938  71.481  35.961  1.00 31.57  ? 151 ARG C CG  1 
ATOM   8291  C CD  . ARG C 1 151 ? 29.764  71.264  35.020  1.00 30.09  ? 151 ARG C CD  1 
ATOM   8292  N NE  . ARG C 1 151 ? 29.539  72.387  34.108  1.00 30.68  ? 151 ARG C NE  1 
ATOM   8293  C CZ  . ARG C 1 151 ? 28.558  73.268  34.201  1.00 29.43  ? 151 ARG C CZ  1 
ATOM   8294  N NH1 . ARG C 1 151 ? 27.811  73.331  35.284  1.00 29.41  ? 151 ARG C NH1 1 
ATOM   8295  N NH2 . ARG C 1 151 ? 28.373  74.149  33.241  1.00 28.67  ? 151 ARG C NH2 1 
ATOM   8296  N N   . GLU C 1 152 ? 30.919  71.416  39.972  1.00 26.87  ? 152 GLU C N   1 
ATOM   8297  C CA  . GLU C 1 152 ? 30.426  72.478  40.833  1.00 27.92  ? 152 GLU C CA  1 
ATOM   8298  C C   . GLU C 1 152 ? 31.385  72.801  41.989  1.00 28.78  ? 152 GLU C C   1 
ATOM   8299  O O   . GLU C 1 152 ? 31.018  73.627  42.820  1.00 23.97  ? 152 GLU C O   1 
ATOM   8300  C CB  . GLU C 1 152 ? 29.049  72.089  41.386  1.00 28.33  ? 152 GLU C CB  1 
ATOM   8301  C CG  . GLU C 1 152 ? 28.019  71.743  40.320  1.00 28.55  ? 152 GLU C CG  1 
ATOM   8302  C CD  . GLU C 1 152 ? 28.104  72.626  39.086  1.00 30.90  ? 152 GLU C CD  1 
ATOM   8303  O OE1 . GLU C 1 152 ? 28.126  72.074  37.942  1.00 27.91  ? 152 GLU C OE1 1 
ATOM   8304  O OE2 . GLU C 1 152 ? 28.170  73.863  39.302  1.00 29.48  ? 152 GLU C OE2 1 
ATOM   8305  N N   . SER C 1 153 ? 32.587  72.172  42.040  1.00 28.50  ? 153 SER C N   1 
ATOM   8306  C CA  . SER C 1 153 ? 33.526  72.348  43.144  1.00 29.90  ? 153 SER C CA  1 
ATOM   8307  C C   . SER C 1 153 ? 33.961  73.802  43.256  1.00 28.77  ? 153 SER C C   1 
ATOM   8308  O O   . SER C 1 153 ? 34.534  74.323  42.314  1.00 31.25  ? 153 SER C O   1 
ATOM   8309  C CB  . SER C 1 153 ? 34.752  71.466  43.000  1.00 32.03  ? 153 SER C CB  1 
ATOM   8310  O OG  . SER C 1 153 ? 35.705  71.741  44.014  1.00 30.51  ? 153 SER C OG  1 
ATOM   8311  N N   . VAL C 1 154 ? 33.732  74.411  44.425  1.00 27.71  ? 154 VAL C N   1 
ATOM   8312  C CA  . VAL C 1 154 ? 34.144  75.779  44.692  1.00 28.74  ? 154 VAL C CA  1 
ATOM   8313  C C   . VAL C 1 154 ? 35.649  75.800  44.966  1.00 30.76  ? 154 VAL C C   1 
ATOM   8314  O O   . VAL C 1 154 ? 36.344  76.763  44.626  1.00 25.94  ? 154 VAL C O   1 
ATOM   8315  C CB  . VAL C 1 154 ? 33.314  76.365  45.856  1.00 32.55  ? 154 VAL C CB  1 
ATOM   8316  C CG1 . VAL C 1 154 ? 33.962  77.604  46.467  1.00 36.41  ? 154 VAL C CG1 1 
ATOM   8317  C CG2 . VAL C 1 154 ? 31.874  76.675  45.454  1.00 30.17  ? 154 VAL C CG2 1 
ATOM   8318  N N   . PHE C 1 155 ? 36.165  74.712  45.553  1.00 32.49  ? 155 PHE C N   1 
ATOM   8319  C CA  . PHE C 1 155 ? 37.591  74.623  45.834  1.00 35.60  ? 155 PHE C CA  1 
ATOM   8320  C C   . PHE C 1 155 ? 38.389  74.663  44.526  1.00 34.15  ? 155 PHE C C   1 
ATOM   8321  O O   . PHE C 1 155 ? 39.381  75.404  44.425  1.00 29.35  ? 155 PHE C O   1 
ATOM   8322  C CB  . PHE C 1 155 ? 37.907  73.374  46.669  1.00 35.18  ? 155 PHE C CB  1 
ATOM   8323  C CG  . PHE C 1 155 ? 39.361  73.265  47.112  1.00 34.73  ? 155 PHE C CG  1 
ATOM   8324  C CD1 . PHE C 1 155 ? 40.337  72.773  46.257  1.00 36.02  ? 155 PHE C CD1 1 
ATOM   8325  C CD2 . PHE C 1 155 ? 39.752  73.645  48.388  1.00 37.17  ? 155 PHE C CD2 1 
ATOM   8326  C CE1 . PHE C 1 155 ? 41.656  72.662  46.663  1.00 34.40  ? 155 PHE C CE1 1 
ATOM   8327  C CE2 . PHE C 1 155 ? 41.078  73.536  48.788  1.00 35.12  ? 155 PHE C CE2 1 
ATOM   8328  C CZ  . PHE C 1 155 ? 42.020  73.032  47.931  1.00 34.91  ? 155 PHE C CZ  1 
ATOM   8329  N N   . ALA C 1 156 ? 37.975  73.838  43.544  1.00 32.39  ? 156 ALA C N   1 
ATOM   8330  C CA  . ALA C 1 156 ? 38.708  73.759  42.286  1.00 31.96  ? 156 ALA C CA  1 
ATOM   8331  C C   . ALA C 1 156 ? 38.658  75.127  41.628  1.00 30.17  ? 156 ALA C C   1 
ATOM   8332  O O   . ALA C 1 156 ? 39.674  75.655  41.189  1.00 34.89  ? 156 ALA C O   1 
ATOM   8333  C CB  . ALA C 1 156 ? 38.190  72.682  41.355  1.00 29.04  ? 156 ALA C CB  1 
ATOM   8334  N N   . LYS C 1 157 ? 37.474  75.714  41.623  1.00 31.13  ? 157 LYS C N   1 
ATOM   8335  C CA  . LYS C 1 157 ? 37.299  76.979  40.950  1.00 34.27  ? 157 LYS C CA  1 
ATOM   8336  C C   . LYS C 1 157 ? 38.262  77.970  41.589  1.00 33.42  ? 157 LYS C C   1 
ATOM   8337  O O   . LYS C 1 157 ? 39.066  78.594  40.892  1.00 31.06  ? 157 LYS C O   1 
ATOM   8338  C CB  . LYS C 1 157 ? 35.848  77.466  40.969  1.00 39.09  ? 157 LYS C CB  1 
ATOM   8339  C CG  . LYS C 1 157 ? 35.548  78.447  39.833  1.00 52.75  ? 157 LYS C CG  1 
ATOM   8340  C CD  . LYS C 1 157 ? 34.264  79.264  39.964  1.00 59.90  ? 157 LYS C CD  1 
ATOM   8341  C CE  . LYS C 1 157 ? 34.061  80.212  38.813  1.00 63.59  ? 157 LYS C CE  1 
ATOM   8342  N NZ  . LYS C 1 157 ? 32.986  81.166  39.103  1.00 63.40  ? 157 LYS C NZ  1 
ATOM   8343  N N   . ARG C 1 158 ? 38.188  78.074  42.923  1.00 37.34  ? 158 ARG C N   1 
ATOM   8344  C CA  . ARG C 1 158 ? 38.897  79.117  43.644  1.00 37.60  ? 158 ARG C CA  1 
ATOM   8345  C C   . ARG C 1 158 ? 40.394  78.819  43.565  1.00 37.66  ? 158 ARG C C   1 
ATOM   8346  O O   . ARG C 1 158 ? 41.184  79.738  43.404  1.00 36.53  ? 158 ARG C O   1 
ATOM   8347  C CB  . ARG C 1 158 ? 38.359  79.323  45.071  1.00 45.77  ? 158 ARG C CB  1 
ATOM   8348  C CG  . ARG C 1 158 ? 37.089  80.160  45.225  1.00 48.84  ? 158 ARG C CG  1 
ATOM   8349  C CD  . ARG C 1 158 ? 36.960  80.867  46.578  1.00 59.34  ? 158 ARG C CD  1 
ATOM   8350  N NE  . ARG C 1 158 ? 35.956  80.334  47.517  1.00 69.12  ? 158 ARG C NE  1 
ATOM   8351  C CZ  . ARG C 1 158 ? 36.025  80.403  48.864  1.00 68.04  ? 158 ARG C CZ  1 
ATOM   8352  N NH1 . ARG C 1 158 ? 35.018  79.951  49.605  1.00 48.37  ? 158 ARG C NH1 1 
ATOM   8353  N NH2 . ARG C 1 158 ? 37.110  80.905  49.462  1.00 71.64  ? 158 ARG C NH2 1 
ATOM   8354  N N   . TYR C 1 159 ? 40.786  77.537  43.625  1.00 38.82  ? 159 TYR C N   1 
ATOM   8355  C CA  . TYR C 1 159 ? 42.198  77.199  43.548  1.00 44.00  ? 159 TYR C CA  1 
ATOM   8356  C C   . TYR C 1 159 ? 42.786  77.760  42.254  1.00 48.88  ? 159 TYR C C   1 
ATOM   8357  O O   . TYR C 1 159 ? 43.869  78.352  42.266  1.00 45.76  ? 159 TYR C O   1 
ATOM   8358  C CB  . TYR C 1 159 ? 42.536  75.705  43.585  1.00 45.11  ? 159 TYR C CB  1 
ATOM   8359  C CG  . TYR C 1 159 ? 44.038  75.519  43.728  1.00 48.00  ? 159 TYR C CG  1 
ATOM   8360  C CD1 . TYR C 1 159 ? 44.667  75.819  44.935  1.00 53.49  ? 159 TYR C CD1 1 
ATOM   8361  C CD2 . TYR C 1 159 ? 44.835  75.127  42.658  1.00 45.21  ? 159 TYR C CD2 1 
ATOM   8362  C CE1 . TYR C 1 159 ? 46.037  75.701  45.087  1.00 52.47  ? 159 TYR C CE1 1 
ATOM   8363  C CE2 . TYR C 1 159 ? 46.208  75.004  42.797  1.00 42.43  ? 159 TYR C CE2 1 
ATOM   8364  C CZ  . TYR C 1 159 ? 46.804  75.286  44.014  1.00 47.12  ? 159 TYR C CZ  1 
ATOM   8365  O OH  . TYR C 1 159 ? 48.146  75.179  44.202  1.00 55.42  ? 159 TYR C OH  1 
ATOM   8366  N N   . GLU C 1 160 ? 42.034  77.575  41.156  1.00 52.99  ? 160 GLU C N   1 
ATOM   8367  C CA  . GLU C 1 160 ? 42.481  77.938  39.824  1.00 53.87  ? 160 GLU C CA  1 
ATOM   8368  C C   . GLU C 1 160 ? 42.505  79.463  39.704  1.00 50.51  ? 160 GLU C C   1 
ATOM   8369  O O   . GLU C 1 160 ? 43.437  79.997  39.128  1.00 52.57  ? 160 GLU C O   1 
ATOM   8370  C CB  . GLU C 1 160 ? 41.638  77.204  38.776  1.00 57.19  ? 160 GLU C CB  1 
ATOM   8371  C CG  . GLU C 1 160 ? 42.365  76.933  37.459  1.00 63.68  ? 160 GLU C CG  1 
ATOM   8372  C CD  . GLU C 1 160 ? 42.432  78.096  36.470  1.00 75.24  ? 160 GLU C CD  1 
ATOM   8373  O OE1 . GLU C 1 160 ? 43.196  78.004  35.472  1.00 66.81  ? 160 GLU C OE1 1 
ATOM   8374  O OE2 . GLU C 1 160 ? 41.693  79.095  36.682  1.00 73.79  ? 160 GLU C OE2 1 
ATOM   8375  N N   . GLU C 1 161 ? 41.516  80.170  40.267  1.00 47.75  ? 161 GLU C N   1 
ATOM   8376  C CA  . GLU C 1 161 ? 41.489  81.625  40.221  1.00 47.12  ? 161 GLU C CA  1 
ATOM   8377  C C   . GLU C 1 161 ? 42.645  82.208  41.049  1.00 53.61  ? 161 GLU C C   1 
ATOM   8378  O O   . GLU C 1 161 ? 43.065  83.336  40.833  1.00 61.69  ? 161 GLU C O   1 
ATOM   8379  C CB  . GLU C 1 161 ? 40.165  82.173  40.769  1.00 48.47  ? 161 GLU C CB  1 
ATOM   8380  C CG  . GLU C 1 161 ? 38.963  82.059  39.830  1.00 49.81  ? 161 GLU C CG  1 
ATOM   8381  C CD  . GLU C 1 161 ? 37.621  82.475  40.434  1.00 53.90  ? 161 GLU C CD  1 
ATOM   8382  O OE1 . GLU C 1 161 ? 36.648  82.661  39.671  1.00 53.50  ? 161 GLU C OE1 1 
ATOM   8383  O OE2 . GLU C 1 161 ? 37.515  82.623  41.676  1.00 48.12  ? 161 GLU C OE2 1 
ATOM   8384  N N   . GLY C 1 162 ? 43.158  81.463  42.031  1.00 51.44  ? 162 GLY C N   1 
ATOM   8385  C CA  . GLY C 1 162 ? 44.170  82.001  42.924  1.00 53.08  ? 162 GLY C CA  1 
ATOM   8386  C C   . GLY C 1 162 ? 43.582  82.285  44.304  1.00 51.59  ? 162 GLY C C   1 
ATOM   8387  O O   . GLY C 1 162 ? 42.768  83.189  44.492  1.00 53.12  ? 162 GLY C O   1 
ATOM   8388  N N   . MET C 1 163 ? 43.951  81.461  45.272  1.00 49.82  ? 163 MET C N   1 
ATOM   8389  C CA  . MET C 1 163 ? 43.430  81.634  46.614  1.00 54.01  ? 163 MET C CA  1 
ATOM   8390  C C   . MET C 1 163 ? 44.553  81.265  47.566  1.00 50.36  ? 163 MET C C   1 
ATOM   8391  O O   . MET C 1 163 ? 45.367  80.405  47.252  1.00 42.15  ? 163 MET C O   1 
ATOM   8392  C CB  . MET C 1 163 ? 42.138  80.829  46.874  1.00 52.43  ? 163 MET C CB  1 
ATOM   8393  C CG  . MET C 1 163 ? 42.309  79.350  47.264  1.00 50.68  ? 163 MET C CG  1 
ATOM   8394  S SD  . MET C 1 163 ? 40.851  78.587  48.022  1.00 45.74  ? 163 MET C SD  1 
ATOM   8395  C CE  . MET C 1 163 ? 41.087  76.924  47.388  1.00 42.70  ? 163 MET C CE  1 
ATOM   8396  N N   . ARG C 1 164 ? 44.579  81.951  48.709  1.00 63.37  ? 164 ARG C N   1 
ATOM   8397  C CA  . ARG C 1 164 ? 45.534  81.667  49.764  1.00 68.64  ? 164 ARG C CA  1 
ATOM   8398  C C   . ARG C 1 164 ? 45.225  80.291  50.361  1.00 62.40  ? 164 ARG C C   1 
ATOM   8399  O O   . ARG C 1 164 ? 44.086  79.827  50.321  1.00 55.09  ? 164 ARG C O   1 
ATOM   8400  C CB  . ARG C 1 164 ? 45.481  82.834  50.762  1.00 81.43  ? 164 ARG C CB  1 
ATOM   8401  C CG  . ARG C 1 164 ? 45.921  84.176  50.186  1.00 95.66  ? 164 ARG C CG  1 
ATOM   8402  C CD  . ARG C 1 164 ? 45.619  85.386  51.080  1.00 104.02 ? 164 ARG C CD  1 
ATOM   8403  N NE  . ARG C 1 164 ? 46.079  85.281  52.475  1.00 113.91 ? 164 ARG C NE  1 
ATOM   8404  C CZ  . ARG C 1 164 ? 47.347  85.219  52.915  1.00 108.59 ? 164 ARG C CZ  1 
ATOM   8405  N NH1 . ARG C 1 164 ? 48.363  85.194  52.066  1.00 102.47 ? 164 ARG C NH1 1 
ATOM   8406  N NH2 . ARG C 1 164 ? 47.594  85.172  54.216  1.00 101.48 ? 164 ARG C NH2 1 
ATOM   8407  N N   . ARG C 1 165 ? 46.263  79.659  50.919  1.00 61.42  ? 165 ARG C N   1 
ATOM   8408  C CA  . ARG C 1 165 ? 46.156  78.391  51.629  1.00 59.97  ? 165 ARG C CA  1 
ATOM   8409  C C   . ARG C 1 165 ? 45.249  78.571  52.854  1.00 54.15  ? 165 ARG C C   1 
ATOM   8410  O O   . ARG C 1 165 ? 44.554  77.639  53.252  1.00 46.24  ? 165 ARG C O   1 
ATOM   8411  C CB  . ARG C 1 165 ? 47.600  77.941  51.905  1.00 64.91  ? 165 ARG C CB  1 
ATOM   8412  C CG  . ARG C 1 165 ? 48.477  77.942  50.653  1.00 75.15  ? 165 ARG C CG  1 
ATOM   8413  C CD  . ARG C 1 165 ? 49.977  78.108  50.888  1.00 79.25  ? 165 ARG C CD  1 
ATOM   8414  N NE  . ARG C 1 165 ? 50.461  76.907  51.583  1.00 77.29  ? 165 ARG C NE  1 
ATOM   8415  C CZ  . ARG C 1 165 ? 51.140  76.858  52.736  1.00 73.11  ? 165 ARG C CZ  1 
ATOM   8416  N NH1 . ARG C 1 165 ? 51.651  77.961  53.279  1.00 60.64  ? 165 ARG C NH1 1 
ATOM   8417  N NH2 . ARG C 1 165 ? 51.326  75.681  53.326  1.00 72.21  ? 165 ARG C NH2 1 
ATOM   8418  N N   . GLU C 1 166 ? 45.234  79.804  53.399  1.00 62.17  ? 166 GLU C N   1 
ATOM   8419  C CA  . GLU C 1 166 ? 44.433  80.237  54.543  1.00 64.43  ? 166 GLU C CA  1 
ATOM   8420  C C   . GLU C 1 166 ? 42.929  80.089  54.289  1.00 61.03  ? 166 GLU C C   1 
ATOM   8421  O O   . GLU C 1 166 ? 42.193  79.902  55.248  1.00 58.25  ? 166 GLU C O   1 
ATOM   8422  C CB  . GLU C 1 166 ? 44.767  81.698  54.881  1.00 69.75  ? 166 GLU C CB  1 
ATOM   8423  C CG  . GLU C 1 166 ? 46.116  81.928  55.577  1.00 75.89  ? 166 GLU C CG  1 
ATOM   8424  C CD  . GLU C 1 166 ? 47.446  81.974  54.807  1.00 77.00  ? 166 GLU C CD  1 
ATOM   8425  O OE1 . GLU C 1 166 ? 48.495  82.165  55.464  1.00 74.33  ? 166 GLU C OE1 1 
ATOM   8426  O OE2 . GLU C 1 166 ? 47.495  81.835  53.568  1.00 83.16  ? 166 GLU C OE2 1 
ATOM   8427  N N   . GLU C 1 167 ? 42.480  80.179  53.017  1.00 56.88  ? 167 GLU C N   1 
ATOM   8428  C CA  . GLU C 1 167 ? 41.072  80.094  52.639  1.00 47.59  ? 167 GLU C CA  1 
ATOM   8429  C C   . GLU C 1 167 ? 40.685  78.675  52.189  1.00 40.36  ? 167 GLU C C   1 
ATOM   8430  O O   . GLU C 1 167 ? 39.533  78.413  51.856  1.00 44.83  ? 167 GLU C O   1 
ATOM   8431  C CB  . GLU C 1 167 ? 40.750  81.051  51.488  1.00 54.94  ? 167 GLU C CB  1 
ATOM   8432  C CG  . GLU C 1 167 ? 41.280  82.482  51.617  1.00 62.08  ? 167 GLU C CG  1 
ATOM   8433  C CD  . GLU C 1 167 ? 41.348  83.227  50.275  1.00 72.46  ? 167 GLU C CD  1 
ATOM   8434  O OE1 . GLU C 1 167 ? 40.341  83.215  49.515  1.00 77.46  ? 167 GLU C OE1 1 
ATOM   8435  O OE2 . GLU C 1 167 ? 42.417  83.807  49.954  1.00 66.75  ? 167 GLU C OE2 1 
ATOM   8436  N N   . HIS C 1 168 ? 41.622  77.727  52.178  1.00 33.60  ? 168 HIS C N   1 
ATOM   8437  C CA  . HIS C 1 168 ? 41.325  76.382  51.713  1.00 32.70  ? 168 HIS C CA  1 
ATOM   8438  C C   . HIS C 1 168 ? 40.112  75.814  52.444  1.00 35.28  ? 168 HIS C C   1 
ATOM   8439  O O   . HIS C 1 168 ? 39.237  75.226  51.800  1.00 33.98  ? 168 HIS C O   1 
ATOM   8440  C CB  . HIS C 1 168 ? 42.564  75.477  51.775  1.00 34.49  ? 168 HIS C CB  1 
ATOM   8441  C CG  . HIS C 1 168 ? 43.576  75.727  50.682  1.00 41.29  ? 168 HIS C CG  1 
ATOM   8442  N ND1 . HIS C 1 168 ? 44.571  74.826  50.355  1.00 44.28  ? 168 HIS C ND1 1 
ATOM   8443  C CD2 . HIS C 1 168 ? 43.738  76.765  49.826  1.00 39.37  ? 168 HIS C CD2 1 
ATOM   8444  C CE1 . HIS C 1 168 ? 45.288  75.310  49.345  1.00 41.74  ? 168 HIS C CE1 1 
ATOM   8445  N NE2 . HIS C 1 168 ? 44.800  76.490  49.011  1.00 40.08  ? 168 HIS C NE2 1 
ATOM   8446  N N   . TRP C 1 169 ? 40.056  76.006  53.781  1.00 39.71  ? 169 TRP C N   1 
ATOM   8447  C CA  . TRP C 1 169 ? 39.117  75.283  54.636  1.00 33.77  ? 169 TRP C CA  1 
ATOM   8448  C C   . TRP C 1 169 ? 37.700  75.800  54.394  1.00 32.25  ? 169 TRP C C   1 
ATOM   8449  O O   . TRP C 1 169 ? 36.735  75.028  54.488  1.00 30.00  ? 169 TRP C O   1 
ATOM   8450  C CB  . TRP C 1 169 ? 39.502  75.355  56.127  1.00 32.16  ? 169 TRP C CB  1 
ATOM   8451  C CG  . TRP C 1 169 ? 39.411  76.731  56.733  1.00 29.40  ? 169 TRP C CG  1 
ATOM   8452  C CD1 . TRP C 1 169 ? 40.418  77.632  56.911  1.00 29.64  ? 169 TRP C CD1 1 
ATOM   8453  C CD2 . TRP C 1 169 ? 38.216  77.364  57.230  1.00 28.98  ? 169 TRP C CD2 1 
ATOM   8454  N NE1 . TRP C 1 169 ? 39.942  78.788  57.463  1.00 27.91  ? 169 TRP C NE1 1 
ATOM   8455  C CE2 . TRP C 1 169 ? 38.592  78.656  57.667  1.00 29.13  ? 169 TRP C CE2 1 
ATOM   8456  C CE3 . TRP C 1 169 ? 36.875  76.968  57.320  1.00 27.30  ? 169 TRP C CE3 1 
ATOM   8457  C CZ2 . TRP C 1 169 ? 37.672  79.553  58.203  1.00 30.40  ? 169 TRP C CZ2 1 
ATOM   8458  C CZ3 . TRP C 1 169 ? 35.974  77.841  57.889  1.00 31.24  ? 169 TRP C CZ3 1 
ATOM   8459  C CH2 . TRP C 1 169 ? 36.367  79.117  58.319  1.00 31.86  ? 169 TRP C CH2 1 
ATOM   8460  N N   . GLU C 1 170 ? 37.615  77.102  54.091  1.00 31.08  ? 170 GLU C N   1 
ATOM   8461  C CA  . GLU C 1 170 ? 36.364  77.772  53.753  1.00 33.59  ? 170 GLU C CA  1 
ATOM   8462  C C   . GLU C 1 170 ? 35.740  77.168  52.490  1.00 31.93  ? 170 GLU C C   1 
ATOM   8463  O O   . GLU C 1 170 ? 34.548  76.853  52.458  1.00 29.43  ? 170 GLU C O   1 
ATOM   8464  C CB  . GLU C 1 170 ? 36.613  79.272  53.565  1.00 35.74  ? 170 GLU C CB  1 
ATOM   8465  C CG  . GLU C 1 170 ? 37.039  79.936  54.868  1.00 43.16  ? 170 GLU C CG  1 
ATOM   8466  C CD  . GLU C 1 170 ? 37.146  81.447  54.833  1.00 54.00  ? 170 GLU C CD  1 
ATOM   8467  O OE1 . GLU C 1 170 ? 38.206  81.965  55.284  1.00 48.95  ? 170 GLU C OE1 1 
ATOM   8468  O OE2 . GLU C 1 170 ? 36.154  82.084  54.382  1.00 55.62  ? 170 GLU C OE2 1 
ATOM   8469  N N   . ALA C 1 171 ? 36.554  77.006  51.445  1.00 29.64  ? 171 ALA C N   1 
ATOM   8470  C CA  . ALA C 1 171 ? 36.062  76.447  50.200  1.00 29.18  ? 171 ALA C CA  1 
ATOM   8471  C C   . ALA C 1 171 ? 35.690  74.990  50.392  1.00 28.17  ? 171 ALA C C   1 
ATOM   8472  O O   . ALA C 1 171 ? 34.770  74.537  49.748  1.00 28.99  ? 171 ALA C O   1 
ATOM   8473  C CB  . ALA C 1 171 ? 37.104  76.589  49.119  1.00 33.99  ? 171 ALA C CB  1 
ATOM   8474  N N   . MET C 1 172 ? 36.434  74.273  51.247  1.00 32.85  ? 172 MET C N   1 
ATOM   8475  C CA  . MET C 1 172 ? 36.194  72.871  51.601  1.00 32.71  ? 172 MET C CA  1 
ATOM   8476  C C   . MET C 1 172 ? 34.904  72.700  52.409  1.00 33.59  ? 172 MET C C   1 
ATOM   8477  O O   . MET C 1 172 ? 34.221  71.664  52.337  1.00 26.87  ? 172 MET C O   1 
ATOM   8478  C CB  . MET C 1 172 ? 37.369  72.345  52.435  1.00 34.75  ? 172 MET C CB  1 
ATOM   8479  C CG  . MET C 1 172 ? 38.629  72.051  51.607  1.00 34.80  ? 172 MET C CG  1 
ATOM   8480  S SD  . MET C 1 172 ? 38.519  70.385  50.930  1.00 35.44  ? 172 MET C SD  1 
ATOM   8481  C CE  . MET C 1 172 ? 39.741  70.591  49.643  1.00 46.22  ? 172 MET C CE  1 
ATOM   8482  N N   . LEU C 1 173 ? 34.589  73.729  53.204  1.00 33.73  ? 173 LEU C N   1 
ATOM   8483  C CA  . LEU C 1 173 ? 33.380  73.706  54.001  1.00 33.31  ? 173 LEU C CA  1 
ATOM   8484  C C   . LEU C 1 173 ? 32.197  73.870  53.052  1.00 32.62  ? 173 LEU C C   1 
ATOM   8485  O O   . LEU C 1 173 ? 31.229  73.112  53.135  1.00 30.23  ? 173 LEU C O   1 
ATOM   8486  C CB  . LEU C 1 173 ? 33.427  74.793  55.075  1.00 31.81  ? 173 LEU C CB  1 
ATOM   8487  C CG  . LEU C 1 173 ? 32.152  74.937  55.910  1.00 30.51  ? 173 LEU C CG  1 
ATOM   8488  C CD1 . LEU C 1 173 ? 31.969  73.721  56.807  1.00 32.83  ? 173 LEU C CD1 1 
ATOM   8489  C CD2 . LEU C 1 173 ? 32.131  76.214  56.686  1.00 27.67  ? 173 LEU C CD2 1 
ATOM   8490  N N   . GLU C 1 174 ? 32.311  74.852  52.146  1.00 31.99  ? 174 GLU C N   1 
ATOM   8491  C CA  . GLU C 1 174 ? 31.271  75.150  51.165  1.00 34.27  ? 174 GLU C CA  1 
ATOM   8492  C C   . GLU C 1 174 ? 30.993  73.955  50.247  1.00 30.90  ? 174 GLU C C   1 
ATOM   8493  O O   . GLU C 1 174 ? 29.843  73.622  49.982  1.00 29.73  ? 174 GLU C O   1 
ATOM   8494  C CB  . GLU C 1 174 ? 31.626  76.395  50.356  1.00 34.44  ? 174 GLU C CB  1 
ATOM   8495  C CG  . GLU C 1 174 ? 30.481  76.874  49.470  1.00 38.04  ? 174 GLU C CG  1 
ATOM   8496  C CD  . GLU C 1 174 ? 29.337  77.587  50.167  1.00 39.02  ? 174 GLU C CD  1 
ATOM   8497  O OE1 . GLU C 1 174 ? 29.441  78.038  51.315  1.00 40.04  ? 174 GLU C OE1 1 
ATOM   8498  O OE2 . GLU C 1 174 ? 28.292  77.692  49.509  1.00 47.71  ? 174 GLU C OE2 1 
ATOM   8499  N N   . ASP C 1 175 ? 32.047  73.294  49.779  1.00 29.37  ? 175 ASP C N   1 
ATOM   8500  C CA  . ASP C 1 175 ? 31.883  72.118  48.943  1.00 29.07  ? 175 ASP C CA  1 
ATOM   8501  C C   . ASP C 1 175 ? 31.276  70.966  49.743  1.00 30.11  ? 175 ASP C C   1 
ATOM   8502  O O   . ASP C 1 175 ? 30.530  70.153  49.209  1.00 27.10  ? 175 ASP C O   1 
ATOM   8503  C CB  . ASP C 1 175 ? 33.219  71.725  48.341  1.00 28.25  ? 175 ASP C CB  1 
ATOM   8504  C CG  . ASP C 1 175 ? 33.628  72.486  47.094  1.00 28.48  ? 175 ASP C CG  1 
ATOM   8505  O OD1 . ASP C 1 175 ? 32.744  73.191  46.517  1.00 27.68  ? 175 ASP C OD1 1 
ATOM   8506  O OD2 . ASP C 1 175 ? 34.819  72.343  46.703  1.00 25.93  ? 175 ASP C OD2 1 
ATOM   8507  N N   . SER C 1 176 ? 31.637  70.885  51.030  1.00 33.10  ? 176 SER C N   1 
ATOM   8508  C CA  . SER C 1 176 ? 31.174  69.811  51.900  1.00 31.26  ? 176 SER C CA  1 
ATOM   8509  C C   . SER C 1 176 ? 29.690  69.988  52.207  1.00 27.18  ? 176 SER C C   1 
ATOM   8510  O O   . SER C 1 176 ? 28.936  69.023  52.190  1.00 28.43  ? 176 SER C O   1 
ATOM   8511  C CB  . SER C 1 176 ? 31.988  69.738  53.175  1.00 31.80  ? 176 SER C CB  1 
ATOM   8512  O OG  . SER C 1 176 ? 33.295  69.251  52.925  1.00 30.70  ? 176 SER C OG  1 
ATOM   8513  N N   . LEU C 1 177 ? 29.272  71.230  52.457  1.00 25.29  ? 177 LEU C N   1 
ATOM   8514  C CA  . LEU C 1 177 ? 27.855  71.526  52.589  1.00 24.57  ? 177 LEU C CA  1 
ATOM   8515  C C   . LEU C 1 177 ? 27.131  71.031  51.341  1.00 23.74  ? 177 LEU C C   1 
ATOM   8516  O O   . LEU C 1 177 ? 26.185  70.255  51.462  1.00 22.51  ? 177 LEU C O   1 
ATOM   8517  C CB  . LEU C 1 177 ? 27.599  73.013  52.823  1.00 24.70  ? 177 LEU C CB  1 
ATOM   8518  C CG  . LEU C 1 177 ? 28.104  73.578  54.151  1.00 27.36  ? 177 LEU C CG  1 
ATOM   8519  C CD1 . LEU C 1 177 ? 28.005  75.105  54.178  1.00 29.12  ? 177 LEU C CD1 1 
ATOM   8520  C CD2 . LEU C 1 177 ? 27.349  72.998  55.323  1.00 27.22  ? 177 LEU C CD2 1 
ATOM   8521  N N   . ASN C 1 178 ? 27.622  71.417  50.149  1.00 23.22  ? 178 ASN C N   1 
ATOM   8522  C CA  . ASN C 1 178 ? 26.953  71.041  48.906  1.00 24.34  ? 178 ASN C CA  1 
ATOM   8523  C C   . ASN C 1 178 ? 26.913  69.531  48.707  1.00 24.05  ? 178 ASN C C   1 
ATOM   8524  O O   . ASN C 1 178 ? 25.875  69.003  48.338  1.00 25.97  ? 178 ASN C O   1 
ATOM   8525  C CB  . ASN C 1 178 ? 27.597  71.680  47.688  1.00 23.63  ? 178 ASN C CB  1 
ATOM   8526  C CG  . ASN C 1 178 ? 27.220  73.134  47.606  1.00 23.64  ? 178 ASN C CG  1 
ATOM   8527  O OD1 . ASN C 1 178 ? 26.237  73.562  48.226  1.00 21.54  ? 178 ASN C OD1 1 
ATOM   8528  N ND2 . ASN C 1 178 ? 27.972  73.891  46.825  1.00 24.02  ? 178 ASN C ND2 1 
ATOM   8529  N N   . MET C 1 179 ? 28.030  68.846  48.955  1.00 24.24  ? 179 MET C N   1 
ATOM   8530  C CA  . MET C 1 179 ? 28.124  67.426  48.640  1.00 25.68  ? 179 MET C CA  1 
ATOM   8531  C C   . MET C 1 179 ? 27.333  66.595  49.650  1.00 25.71  ? 179 MET C C   1 
ATOM   8532  O O   . MET C 1 179 ? 26.712  65.608  49.270  1.00 26.39  ? 179 MET C O   1 
ATOM   8533  C CB  . MET C 1 179 ? 29.584  66.941  48.574  1.00 25.65  ? 179 MET C CB  1 
ATOM   8534  C CG  . MET C 1 179 ? 29.715  65.492  48.146  1.00 25.52  ? 179 MET C CG  1 
ATOM   8535  S SD  . MET C 1 179 ? 31.322  64.722  48.390  1.00 28.58  ? 179 MET C SD  1 
ATOM   8536  C CE  . MET C 1 179 ? 31.370  64.523  50.174  1.00 26.72  ? 179 MET C CE  1 
ATOM   8537  N N   . LEU C 1 180 ? 27.372  66.986  50.933  1.00 28.44  ? 180 LEU C N   1 
ATOM   8538  C CA  . LEU C 1 180 ? 26.614  66.293  51.971  1.00 29.33  ? 180 LEU C CA  1 
ATOM   8539  C C   . LEU C 1 180 ? 25.109  66.384  51.679  1.00 26.97  ? 180 LEU C C   1 
ATOM   8540  O O   . LEU C 1 180 ? 24.372  65.389  51.789  1.00 25.39  ? 180 LEU C O   1 
ATOM   8541  C CB  . LEU C 1 180 ? 26.976  66.832  53.358  1.00 28.90  ? 180 LEU C CB  1 
ATOM   8542  C CG  . LEU C 1 180 ? 28.348  66.407  53.906  1.00 29.83  ? 180 LEU C CG  1 
ATOM   8543  C CD1 . LEU C 1 180 ? 28.718  67.212  55.139  1.00 29.24  ? 180 LEU C CD1 1 
ATOM   8544  C CD2 . LEU C 1 180 ? 28.469  64.900  54.190  1.00 28.24  ? 180 LEU C CD2 1 
ATOM   8545  N N   . ALA C 1 181 ? 24.680  67.577  51.268  1.00 23.28  ? 181 ALA C N   1 
ATOM   8546  C CA  . ALA C 1 181 ? 23.303  67.807  50.884  1.00 25.71  ? 181 ALA C CA  1 
ATOM   8547  C C   . ALA C 1 181 ? 22.942  66.906  49.698  1.00 28.56  ? 181 ALA C C   1 
ATOM   8548  O O   . ALA C 1 181 ? 21.879  66.296  49.691  1.00 31.35  ? 181 ALA C O   1 
ATOM   8549  C CB  . ALA C 1 181 ? 23.116  69.276  50.591  1.00 24.26  ? 181 ALA C CB  1 
ATOM   8550  N N   . ALA C 1 182 ? 23.878  66.724  48.762  1.00 26.23  ? 182 ALA C N   1 
ATOM   8551  C CA  . ALA C 1 182 ? 23.637  65.908  47.589  1.00 27.42  ? 182 ALA C CA  1 
ATOM   8552  C C   . ALA C 1 182 ? 23.515  64.418  47.889  1.00 28.55  ? 182 ALA C C   1 
ATOM   8553  O O   . ALA C 1 182 ? 22.889  63.712  47.112  1.00 31.57  ? 182 ALA C O   1 
ATOM   8554  C CB  . ALA C 1 182 ? 24.748  66.124  46.594  1.00 29.38  ? 182 ALA C CB  1 
ATOM   8555  N N   . LEU C 1 183 ? 24.159  63.896  48.939  1.00 29.06  ? 183 LEU C N   1 
ATOM   8556  C CA  . LEU C 1 183 ? 24.350  62.449  49.033  1.00 28.50  ? 183 LEU C CA  1 
ATOM   8557  C C   . LEU C 1 183 ? 23.035  61.704  49.239  1.00 25.19  ? 183 LEU C C   1 
ATOM   8558  O O   . LEU C 1 183 ? 22.810  60.675  48.631  1.00 25.14  ? 183 LEU C O   1 
ATOM   8559  C CB  . LEU C 1 183 ? 25.352  62.041  50.108  1.00 31.12  ? 183 LEU C CB  1 
ATOM   8560  C CG  . LEU C 1 183 ? 26.776  62.568  49.927  1.00 29.65  ? 183 LEU C CG  1 
ATOM   8561  C CD1 . LEU C 1 183 ? 27.630  62.145  51.110  1.00 32.45  ? 183 LEU C CD1 1 
ATOM   8562  C CD2 . LEU C 1 183 ? 27.341  62.066  48.639  1.00 28.99  ? 183 LEU C CD2 1 
ATOM   8563  N N   . PRO C 1 184 ? 22.120  62.144  50.107  1.00 25.62  ? 184 PRO C N   1 
ATOM   8564  C CA  . PRO C 1 184 ? 20.846  61.454  50.254  1.00 26.88  ? 184 PRO C CA  1 
ATOM   8565  C C   . PRO C 1 184 ? 20.085  61.411  48.934  1.00 25.87  ? 184 PRO C C   1 
ATOM   8566  O O   . PRO C 1 184 ? 19.467  60.397  48.609  1.00 27.96  ? 184 PRO C O   1 
ATOM   8567  C CB  . PRO C 1 184 ? 20.106  62.283  51.333  1.00 26.97  ? 184 PRO C CB  1 
ATOM   8568  C CG  . PRO C 1 184 ? 21.174  63.002  52.073  1.00 26.37  ? 184 PRO C CG  1 
ATOM   8569  C CD  . PRO C 1 184 ? 22.239  63.303  51.005  1.00 29.01  ? 184 PRO C CD  1 
ATOM   8570  N N   . VAL C 1 185 ? 20.154  62.513  48.182  1.00 24.96  ? 185 VAL C N   1 
ATOM   8571  C CA  . VAL C 1 185 ? 19.476  62.643  46.891  1.00 24.20  ? 185 VAL C CA  1 
ATOM   8572  C C   . VAL C 1 185 ? 20.021  61.643  45.869  1.00 22.81  ? 185 VAL C C   1 
ATOM   8573  O O   . VAL C 1 185 ? 19.274  61.006  45.141  1.00 23.79  ? 185 VAL C O   1 
ATOM   8574  C CB  . VAL C 1 185 ? 19.599  64.075  46.345  1.00 24.47  ? 185 VAL C CB  1 
ATOM   8575  C CG1 . VAL C 1 185 ? 18.926  64.211  44.993  1.00 26.76  ? 185 VAL C CG1 1 
ATOM   8576  C CG2 . VAL C 1 185 ? 19.047  65.113  47.317  1.00 26.73  ? 185 VAL C CG2 1 
ATOM   8577  N N   . ILE C 1 186 ? 21.341  61.543  45.778  1.00 23.88  ? 186 ILE C N   1 
ATOM   8578  C CA  . ILE C 1 186 ? 21.977  60.643  44.830  1.00 24.72  ? 186 ILE C CA  1 
ATOM   8579  C C   . ILE C 1 186 ? 21.674  59.205  45.253  1.00 27.13  ? 186 ILE C C   1 
ATOM   8580  O O   . ILE C 1 186 ? 21.328  58.340  44.431  1.00 28.55  ? 186 ILE C O   1 
ATOM   8581  C CB  . ILE C 1 186 ? 23.488  60.953  44.774  1.00 22.62  ? 186 ILE C CB  1 
ATOM   8582  C CG1 . ILE C 1 186 ? 23.779  62.210  43.968  1.00 23.06  ? 186 ILE C CG1 1 
ATOM   8583  C CG2 . ILE C 1 186 ? 24.285  59.767  44.242  1.00 24.10  ? 186 ILE C CG2 1 
ATOM   8584  C CD1 . ILE C 1 186 ? 25.090  62.885  44.314  1.00 23.20  ? 186 ILE C CD1 1 
ATOM   8585  N N   . ALA C 1 187 ? 21.829  58.961  46.562  1.00 26.77  ? 187 ALA C N   1 
ATOM   8586  C CA  . ALA C 1 187 ? 21.676  57.628  47.099  1.00 27.46  ? 187 ALA C CA  1 
ATOM   8587  C C   . ALA C 1 187 ? 20.243  57.172  46.891  1.00 24.42  ? 187 ALA C C   1 
ATOM   8588  O O   . ALA C 1 187 ? 20.012  56.028  46.512  1.00 24.51  ? 187 ALA C O   1 
ATOM   8589  C CB  . ALA C 1 187 ? 22.082  57.606  48.557  1.00 30.52  ? 187 ALA C CB  1 
ATOM   8590  N N   . ALA C 1 188 ? 19.296  58.082  47.126  1.00 23.78  ? 188 ALA C N   1 
ATOM   8591  C CA  . ALA C 1 188 ? 17.884  57.740  47.006  1.00 24.49  ? 188 ALA C CA  1 
ATOM   8592  C C   . ALA C 1 188 ? 17.558  57.442  45.553  1.00 26.47  ? 188 ALA C C   1 
ATOM   8593  O O   . ALA C 1 188 ? 16.887  56.445  45.263  1.00 30.30  ? 188 ALA C O   1 
ATOM   8594  C CB  . ALA C 1 188 ? 17.028  58.861  47.538  1.00 24.41  ? 188 ALA C CB  1 
ATOM   8595  N N   . TYR C 1 189 ? 18.063  58.314  44.660  1.00 26.35  ? 189 TYR C N   1 
ATOM   8596  C CA  . TYR C 1 189 ? 17.905  58.159  43.221  1.00 25.57  ? 189 TYR C CA  1 
ATOM   8597  C C   . TYR C 1 189 ? 18.312  56.747  42.812  1.00 24.60  ? 189 TYR C C   1 
ATOM   8598  O O   . TYR C 1 189 ? 17.573  56.072  42.119  1.00 28.31  ? 189 TYR C O   1 
ATOM   8599  C CB  . TYR C 1 189 ? 18.683  59.206  42.426  1.00 24.75  ? 189 TYR C CB  1 
ATOM   8600  C CG  . TYR C 1 189 ? 18.253  59.219  40.969  1.00 27.53  ? 189 TYR C CG  1 
ATOM   8601  C CD1 . TYR C 1 189 ? 18.705  58.261  40.071  1.00 28.65  ? 189 TYR C CD1 1 
ATOM   8602  C CD2 . TYR C 1 189 ? 17.340  60.161  40.505  1.00 30.88  ? 189 TYR C CD2 1 
ATOM   8603  C CE1 . TYR C 1 189 ? 18.294  58.249  38.750  1.00 28.37  ? 189 TYR C CE1 1 
ATOM   8604  C CE2 . TYR C 1 189 ? 16.894  60.148  39.193  1.00 30.15  ? 189 TYR C CE2 1 
ATOM   8605  C CZ  . TYR C 1 189 ? 17.385  59.199  38.311  1.00 31.59  ? 189 TYR C CZ  1 
ATOM   8606  O OH  . TYR C 1 189 ? 16.983  59.240  37.005  1.00 32.95  ? 189 TYR C OH  1 
ATOM   8607  N N   . ILE C 1 190 ? 19.466  56.298  43.296  1.00 23.91  ? 190 ILE C N   1 
ATOM   8608  C CA  . ILE C 1 190 ? 19.979  54.980  42.972  1.00 23.24  ? 190 ILE C CA  1 
ATOM   8609  C C   . ILE C 1 190 ? 19.045  53.909  43.529  1.00 23.42  ? 190 ILE C C   1 
ATOM   8610  O O   . ILE C 1 190 ? 18.681  52.965  42.839  1.00 23.01  ? 190 ILE C O   1 
ATOM   8611  C CB  . ILE C 1 190 ? 21.398  54.844  43.540  1.00 21.92  ? 190 ILE C CB  1 
ATOM   8612  C CG1 . ILE C 1 190 ? 22.357  55.796  42.841  1.00 21.24  ? 190 ILE C CG1 1 
ATOM   8613  C CG2 . ILE C 1 190 ? 21.837  53.387  43.460  1.00 23.28  ? 190 ILE C CG2 1 
ATOM   8614  C CD1 . ILE C 1 190 ? 23.767  55.897  43.408  1.00 19.53  ? 190 ILE C CD1 1 
ATOM   8615  N N   . TYR C 1 191 ? 18.659  54.058  44.802  1.00 26.56  ? 191 TYR C N   1 
ATOM   8616  C CA  . TYR C 1 191 ? 17.738  53.128  45.457  1.00 26.39  ? 191 TYR C CA  1 
ATOM   8617  C C   . TYR C 1 191 ? 16.433  53.000  44.658  1.00 25.31  ? 191 TYR C C   1 
ATOM   8618  O O   . TYR C 1 191 ? 16.013  51.883  44.308  1.00 22.43  ? 191 TYR C O   1 
ATOM   8619  C CB  . TYR C 1 191 ? 17.498  53.604  46.900  1.00 28.32  ? 191 TYR C CB  1 
ATOM   8620  C CG  . TYR C 1 191 ? 16.762  52.589  47.766  1.00 27.81  ? 191 TYR C CG  1 
ATOM   8621  C CD1 . TYR C 1 191 ? 17.433  51.468  48.241  1.00 28.12  ? 191 TYR C CD1 1 
ATOM   8622  C CD2 . TYR C 1 191 ? 15.400  52.717  48.062  1.00 26.33  ? 191 TYR C CD2 1 
ATOM   8623  C CE1 . TYR C 1 191 ? 16.782  50.519  49.013  1.00 30.36  ? 191 TYR C CE1 1 
ATOM   8624  C CE2 . TYR C 1 191 ? 14.736  51.764  48.822  1.00 27.61  ? 191 TYR C CE2 1 
ATOM   8625  C CZ  . TYR C 1 191 ? 15.436  50.669  49.314  1.00 29.70  ? 191 TYR C CZ  1 
ATOM   8626  O OH  . TYR C 1 191 ? 14.872  49.703  50.097  1.00 25.92  ? 191 TYR C OH  1 
ATOM   8627  N N   . ARG C 1 192 ? 15.797  54.152  44.361  1.00 23.80  ? 192 ARG C N   1 
ATOM   8628  C CA  . ARG C 1 192 ? 14.511  54.147  43.678  1.00 24.20  ? 192 ARG C CA  1 
ATOM   8629  C C   . ARG C 1 192 ? 14.669  53.495  42.301  1.00 26.34  ? 192 ARG C C   1 
ATOM   8630  O O   . ARG C 1 192 ? 13.902  52.613  41.944  1.00 23.28  ? 192 ARG C O   1 
ATOM   8631  C CB  . ARG C 1 192 ? 13.927  55.559  43.598  1.00 24.75  ? 192 ARG C CB  1 
ATOM   8632  C CG  . ARG C 1 192 ? 13.697  56.292  44.920  1.00 25.37  ? 192 ARG C CG  1 
ATOM   8633  C CD  . ARG C 1 192 ? 12.751  55.547  45.899  1.00 27.00  ? 192 ARG C CD  1 
ATOM   8634  N NE  . ARG C 1 192 ? 11.409  55.402  45.321  1.00 26.73  ? 192 ARG C NE  1 
ATOM   8635  C CZ  . ARG C 1 192 ? 10.341  54.807  45.860  1.00 29.42  ? 192 ARG C CZ  1 
ATOM   8636  N NH1 . ARG C 1 192 ? 10.388  54.290  47.089  1.00 30.48  ? 192 ARG C NH1 1 
ATOM   8637  N NH2 . ARG C 1 192 ? 9.213   54.729  45.155  1.00 28.00  ? 192 ARG C NH2 1 
ATOM   8638  N N   . ARG C 1 193 ? 15.724  53.857  41.545  1.00 29.80  ? 193 ARG C N   1 
ATOM   8639  C CA  . ARG C 1 193 ? 15.845  53.391  40.166  1.00 26.24  ? 193 ARG C CA  1 
ATOM   8640  C C   . ARG C 1 193 ? 16.097  51.888  40.147  1.00 26.58  ? 193 ARG C C   1 
ATOM   8641  O O   . ARG C 1 193 ? 15.612  51.184  39.268  1.00 28.55  ? 193 ARG C O   1 
ATOM   8642  C CB  . ARG C 1 193 ? 16.956  54.077  39.365  1.00 26.12  ? 193 ARG C CB  1 
ATOM   8643  C CG  . ARG C 1 193 ? 16.954  53.721  37.877  1.00 26.63  ? 193 ARG C CG  1 
ATOM   8644  C CD  . ARG C 1 193 ? 17.922  54.495  37.017  1.00 24.87  ? 193 ARG C CD  1 
ATOM   8645  N NE  . ARG C 1 193 ? 18.081  53.908  35.675  1.00 27.21  ? 193 ARG C NE  1 
ATOM   8646  C CZ  . ARG C 1 193 ? 19.224  53.553  35.072  1.00 28.02  ? 193 ARG C CZ  1 
ATOM   8647  N NH1 . ARG C 1 193 ? 20.388  53.897  35.588  1.00 32.85  ? 193 ARG C NH1 1 
ATOM   8648  N NH2 . ARG C 1 193 ? 19.224  52.821  33.971  1.00 29.68  ? 193 ARG C NH2 1 
ATOM   8649  N N   . LYS C 1 194 ? 16.910  51.391  41.079  1.00 26.79  ? 194 LYS C N   1 
ATOM   8650  C CA  . LYS C 1 194 ? 17.300  49.992  41.021  1.00 26.87  ? 194 LYS C CA  1 
ATOM   8651  C C   . LYS C 1 194 ? 16.198  49.096  41.580  1.00 27.49  ? 194 LYS C C   1 
ATOM   8652  O O   . LYS C 1 194 ? 15.946  48.043  41.020  1.00 26.63  ? 194 LYS C O   1 
ATOM   8653  C CB  . LYS C 1 194 ? 18.600  49.716  41.778  1.00 26.73  ? 194 LYS C CB  1 
ATOM   8654  C CG  . LYS C 1 194 ? 19.841  50.308  41.144  1.00 29.09  ? 194 LYS C CG  1 
ATOM   8655  C CD  . LYS C 1 194 ? 21.127  49.983  41.893  1.00 28.74  ? 194 LYS C CD  1 
ATOM   8656  C CE  . LYS C 1 194 ? 21.381  48.513  42.047  1.00 28.29  ? 194 LYS C CE  1 
ATOM   8657  N NZ  . LYS C 1 194 ? 21.729  47.947  40.754  1.00 29.37  ? 194 LYS C NZ  1 
ATOM   8658  N N   . TYR C 1 195 ? 15.539  49.531  42.663  1.00 29.44  ? 195 TYR C N   1 
ATOM   8659  C CA  . TYR C 1 195 ? 14.829  48.618  43.549  1.00 31.32  ? 195 TYR C CA  1 
ATOM   8660  C C   . TYR C 1 195 ? 13.318  48.877  43.620  1.00 28.77  ? 195 TYR C C   1 
ATOM   8661  O O   . TYR C 1 195 ? 12.587  47.989  44.029  1.00 27.87  ? 195 TYR C O   1 
ATOM   8662  C CB  . TYR C 1 195 ? 15.483  48.740  44.936  1.00 32.16  ? 195 TYR C CB  1 
ATOM   8663  C CG  . TYR C 1 195 ? 16.959  48.365  44.990  1.00 30.35  ? 195 TYR C CG  1 
ATOM   8664  C CD1 . TYR C 1 195 ? 17.429  47.160  44.457  1.00 29.84  ? 195 TYR C CD1 1 
ATOM   8665  C CD2 . TYR C 1 195 ? 17.886  49.240  45.531  1.00 26.83  ? 195 TYR C CD2 1 
ATOM   8666  C CE1 . TYR C 1 195 ? 18.775  46.827  44.508  1.00 29.04  ? 195 TYR C CE1 1 
ATOM   8667  C CE2 . TYR C 1 195 ? 19.230  48.917  45.588  1.00 28.94  ? 195 TYR C CE2 1 
ATOM   8668  C CZ  . TYR C 1 195 ? 19.680  47.703  45.088  1.00 30.04  ? 195 TYR C CZ  1 
ATOM   8669  O OH  . TYR C 1 195 ? 21.028  47.418  45.130  1.00 30.51  ? 195 TYR C OH  1 
ATOM   8670  N N   . LYS C 1 196 ? 12.849  50.076  43.260  1.00 28.58  ? 196 LYS C N   1 
ATOM   8671  C CA  . LYS C 1 196 ? 11.474  50.482  43.518  1.00 28.35  ? 196 LYS C CA  1 
ATOM   8672  C C   . LYS C 1 196 ? 10.815  51.115  42.292  1.00 27.00  ? 196 LYS C C   1 
ATOM   8673  O O   . LYS C 1 196 ? 10.188  52.166  42.385  1.00 28.63  ? 196 LYS C O   1 
ATOM   8674  C CB  . LYS C 1 196 ? 11.479  51.498  44.666  1.00 29.47  ? 196 LYS C CB  1 
ATOM   8675  C CG  . LYS C 1 196 ? 11.984  51.001  46.008  1.00 29.90  ? 196 LYS C CG  1 
ATOM   8676  C CD  . LYS C 1 196 ? 11.115  49.904  46.605  1.00 30.37  ? 196 LYS C CD  1 
ATOM   8677  C CE  . LYS C 1 196 ? 11.558  49.607  47.989  1.00 34.32  ? 196 LYS C CE  1 
ATOM   8678  N NZ  . LYS C 1 196 ? 11.069  48.292  48.375  1.00 38.02  ? 196 LYS C NZ  1 
ATOM   8679  N N   . GLY C 1 197 ? 10.992  50.497  41.130  1.00 29.32  ? 197 GLY C N   1 
ATOM   8680  C CA  . GLY C 1 197 ? 10.228  50.858  39.945  1.00 31.99  ? 197 GLY C CA  1 
ATOM   8681  C C   . GLY C 1 197 ? 10.478  52.282  39.440  1.00 32.66  ? 197 GLY C C   1 
ATOM   8682  O O   . GLY C 1 197 ? 9.640   52.833  38.757  1.00 36.28  ? 197 GLY C O   1 
ATOM   8683  N N   . ASP C 1 198 ? 11.637  52.879  39.727  1.00 33.03  ? 198 ASP C N   1 
ATOM   8684  C CA  . ASP C 1 198 ? 12.063  54.086  39.029  1.00 33.73  ? 198 ASP C CA  1 
ATOM   8685  C C   . ASP C 1 198 ? 11.017  55.196  39.194  1.00 34.59  ? 198 ASP C C   1 
ATOM   8686  O O   . ASP C 1 198 ? 10.790  56.011  38.307  1.00 33.49  ? 198 ASP C O   1 
ATOM   8687  C CB  . ASP C 1 198 ? 12.414  53.772  37.580  1.00 32.23  ? 198 ASP C CB  1 
ATOM   8688  C CG  . ASP C 1 198 ? 13.253  54.801  36.834  1.00 28.98  ? 198 ASP C CG  1 
ATOM   8689  O OD1 . ASP C 1 198 ? 13.961  55.587  37.515  1.00 29.20  ? 198 ASP C OD1 1 
ATOM   8690  O OD2 . ASP C 1 198 ? 13.162  54.814  35.582  1.00 25.84  ? 198 ASP C OD2 1 
ATOM   8691  N N   . THR C 1 199 ? 10.431  55.242  40.381  1.00 36.70  ? 199 THR C N   1 
ATOM   8692  C CA  . THR C 1 199 ? 9.529   56.289  40.825  1.00 40.55  ? 199 THR C CA  1 
ATOM   8693  C C   . THR C 1 199 ? 10.335  57.188  41.760  1.00 34.37  ? 199 THR C C   1 
ATOM   8694  O O   . THR C 1 199 ? 11.072  56.680  42.590  1.00 30.66  ? 199 THR C O   1 
ATOM   8695  C CB  . THR C 1 199 ? 8.381   55.542  41.510  1.00 43.10  ? 199 THR C CB  1 
ATOM   8696  O OG1 . THR C 1 199 ? 7.704   55.013  40.373  1.00 44.07  ? 199 THR C OG1 1 
ATOM   8697  C CG2 . THR C 1 199 ? 7.497   56.422  42.371  1.00 51.39  ? 199 THR C CG2 1 
ATOM   8698  N N   . HIS C 1 200 ? 10.253  58.511  41.629  1.00 34.37  ? 200 HIS C N   1 
ATOM   8699  C CA  . HIS C 1 200 ? 11.182  59.349  42.384  1.00 34.07  ? 200 HIS C CA  1 
ATOM   8700  C C   . HIS C 1 200 ? 10.422  60.228  43.363  1.00 33.75  ? 200 HIS C C   1 
ATOM   8701  O O   . HIS C 1 200 ? 9.422   60.827  42.986  1.00 34.76  ? 200 HIS C O   1 
ATOM   8702  C CB  . HIS C 1 200 ? 12.173  60.055  41.455  1.00 32.27  ? 200 HIS C CB  1 
ATOM   8703  C CG  . HIS C 1 200 ? 12.957  59.012  40.725  1.00 32.43  ? 200 HIS C CG  1 
ATOM   8704  N ND1 . HIS C 1 200 ? 14.031  58.367  41.298  1.00 30.95  ? 200 HIS C ND1 1 
ATOM   8705  C CD2 . HIS C 1 200 ? 12.741  58.403  39.556  1.00 32.00  ? 200 HIS C CD2 1 
ATOM   8706  C CE1 . HIS C 1 200 ? 14.483  57.449  40.454  1.00 33.73  ? 200 HIS C CE1 1 
ATOM   8707  N NE2 . HIS C 1 200 ? 13.713  57.444  39.391  1.00 32.57  ? 200 HIS C NE2 1 
ATOM   8708  N N   . ILE C 1 201 ? 10.911  60.267  44.615  1.00 30.61  ? 201 ILE C N   1 
ATOM   8709  C CA  . ILE C 1 201 ? 10.299  61.073  45.653  1.00 27.91  ? 201 ILE C CA  1 
ATOM   8710  C C   . ILE C 1 201 ? 11.244  62.207  45.963  1.00 26.03  ? 201 ILE C C   1 
ATOM   8711  O O   . ILE C 1 201 ? 12.423  61.959  46.169  1.00 26.38  ? 201 ILE C O   1 
ATOM   8712  C CB  . ILE C 1 201 ? 9.995   60.249  46.911  1.00 27.24  ? 201 ILE C CB  1 
ATOM   8713  C CG1 . ILE C 1 201 ? 9.117   59.054  46.590  1.00 26.17  ? 201 ILE C CG1 1 
ATOM   8714  C CG2 . ILE C 1 201 ? 9.359   61.145  47.965  1.00 26.25  ? 201 ILE C CG2 1 
ATOM   8715  C CD1 . ILE C 1 201 ? 9.347   57.880  47.517  1.00 26.76  ? 201 ILE C CD1 1 
ATOM   8716  N N   . ALA C 1 202 ? 10.703  63.422  45.980  1.00 26.00  ? 202 ALA C N   1 
ATOM   8717  C CA  . ALA C 1 202 ? 11.491  64.623  46.185  1.00 28.49  ? 202 ALA C CA  1 
ATOM   8718  C C   . ALA C 1 202 ? 11.806  64.806  47.671  1.00 30.33  ? 202 ALA C C   1 
ATOM   8719  O O   . ALA C 1 202 ? 11.144  64.269  48.551  1.00 31.50  ? 202 ALA C O   1 
ATOM   8720  C CB  . ALA C 1 202 ? 10.719  65.824  45.644  1.00 30.05  ? 202 ALA C CB  1 
ATOM   8721  N N   . PRO C 1 203 ? 12.799  65.643  48.006  1.00 31.79  ? 203 PRO C N   1 
ATOM   8722  C CA  . PRO C 1 203 ? 13.067  65.999  49.392  1.00 32.54  ? 203 PRO C CA  1 
ATOM   8723  C C   . PRO C 1 203 ? 11.836  66.649  49.994  1.00 31.54  ? 203 PRO C C   1 
ATOM   8724  O O   . PRO C 1 203 ? 11.239  67.469  49.337  1.00 34.24  ? 203 PRO C O   1 
ATOM   8725  C CB  . PRO C 1 203 ? 14.205  67.022  49.327  1.00 33.28  ? 203 PRO C CB  1 
ATOM   8726  C CG  . PRO C 1 203 ? 14.773  66.925  47.926  1.00 34.14  ? 203 PRO C CG  1 
ATOM   8727  C CD  . PRO C 1 203 ? 13.724  66.264  47.050  1.00 34.29  ? 203 PRO C CD  1 
ATOM   8728  N N   . ASP C 1 204 ? 11.521  66.337  51.250  1.00 33.39  ? 204 ASP C N   1 
ATOM   8729  C CA  . ASP C 1 204 ? 10.603  67.139  52.036  1.00 34.06  ? 204 ASP C CA  1 
ATOM   8730  C C   . ASP C 1 204 ? 11.418  68.210  52.729  1.00 33.72  ? 204 ASP C C   1 
ATOM   8731  O O   . ASP C 1 204 ? 12.290  67.853  53.503  1.00 32.65  ? 204 ASP C O   1 
ATOM   8732  C CB  . ASP C 1 204 ? 9.881   66.294  53.076  1.00 37.41  ? 204 ASP C CB  1 
ATOM   8733  C CG  . ASP C 1 204 ? 8.921   67.009  54.020  1.00 39.10  ? 204 ASP C CG  1 
ATOM   8734  O OD1 . ASP C 1 204 ? 8.994   68.266  54.134  1.00 36.85  ? 204 ASP C OD1 1 
ATOM   8735  O OD2 . ASP C 1 204 ? 8.110   66.288  54.652  1.00 42.90  ? 204 ASP C OD2 1 
ATOM   8736  N N   . PRO C 1 205 ? 11.116  69.520  52.533  1.00 38.67  ? 205 PRO C N   1 
ATOM   8737  C CA  . PRO C 1 205 ? 11.911  70.605  53.123  1.00 37.13  ? 205 PRO C CA  1 
ATOM   8738  C C   . PRO C 1 205 ? 11.703  70.806  54.629  1.00 40.65  ? 205 PRO C C   1 
ATOM   8739  O O   . PRO C 1 205 ? 12.401  71.634  55.229  1.00 40.73  ? 205 PRO C O   1 
ATOM   8740  C CB  . PRO C 1 205 ? 11.446  71.828  52.307  1.00 35.79  ? 205 PRO C CB  1 
ATOM   8741  C CG  . PRO C 1 205 ? 9.981   71.529  52.057  1.00 37.39  ? 205 PRO C CG  1 
ATOM   8742  C CD  . PRO C 1 205 ? 9.957   70.031  51.779  1.00 37.94  ? 205 PRO C CD  1 
ATOM   8743  N N   . ASN C 1 206 ? 10.758  70.048  55.225  1.00 37.19  ? 206 ASN C N   1 
ATOM   8744  C CA  . ASN C 1 206 ? 10.555  70.056  56.666  1.00 39.28  ? 206 ASN C CA  1 
ATOM   8745  C C   . ASN C 1 206 ? 11.340  68.955  57.391  1.00 38.39  ? 206 ASN C C   1 
ATOM   8746  O O   . ASN C 1 206 ? 11.380  68.982  58.612  1.00 38.26  ? 206 ASN C O   1 
ATOM   8747  C CB  . ASN C 1 206 ? 9.079   69.991  57.049  1.00 39.04  ? 206 ASN C CB  1 
ATOM   8748  C CG  . ASN C 1 206 ? 8.327   71.245  56.663  1.00 46.49  ? 206 ASN C CG  1 
ATOM   8749  O OD1 . ASN C 1 206 ? 8.866   72.353  56.746  1.00 48.05  ? 206 ASN C OD1 1 
ATOM   8750  N ND2 . ASN C 1 206 ? 7.096   71.107  56.195  1.00 50.00  ? 206 ASN C ND2 1 
ATOM   8751  N N   . LEU C 1 207 ? 11.970  67.999  56.694  1.00 33.83  ? 207 LEU C N   1 
ATOM   8752  C CA  . LEU C 1 207 ? 12.690  66.943  57.397  1.00 30.87  ? 207 LEU C CA  1 
ATOM   8753  C C   . LEU C 1 207 ? 14.176  67.266  57.551  1.00 28.43  ? 207 LEU C C   1 
ATOM   8754  O O   . LEU C 1 207 ? 14.781  67.964  56.744  1.00 27.44  ? 207 LEU C O   1 
ATOM   8755  C CB  . LEU C 1 207 ? 12.521  65.601  56.697  1.00 31.92  ? 207 LEU C CB  1 
ATOM   8756  C CG  . LEU C 1 207 ? 11.082  65.104  56.561  1.00 33.10  ? 207 LEU C CG  1 
ATOM   8757  C CD1 . LEU C 1 207 ? 11.058  63.879  55.663  1.00 34.37  ? 207 LEU C CD1 1 
ATOM   8758  C CD2 . LEU C 1 207 ? 10.498  64.764  57.905  1.00 32.92  ? 207 LEU C CD2 1 
ATOM   8759  N N   . ASP C 1 208 ? 14.761  66.733  58.623  1.00 26.06  ? 208 ASP C N   1 
ATOM   8760  C CA  . ASP C 1 208 ? 16.198  66.684  58.779  1.00 26.32  ? 208 ASP C CA  1 
ATOM   8761  C C   . ASP C 1 208 ? 16.813  65.747  57.725  1.00 28.44  ? 208 ASP C C   1 
ATOM   8762  O O   . ASP C 1 208 ? 16.135  64.926  57.089  1.00 28.76  ? 208 ASP C O   1 
ATOM   8763  C CB  . ASP C 1 208 ? 16.537  66.330  60.221  1.00 27.72  ? 208 ASP C CB  1 
ATOM   8764  C CG  . ASP C 1 208 ? 15.920  65.024  60.690  1.00 27.24  ? 208 ASP C CG  1 
ATOM   8765  O OD1 . ASP C 1 208 ? 14.722  65.010  61.028  1.00 25.75  ? 208 ASP C OD1 1 
ATOM   8766  O OD2 . ASP C 1 208 ? 16.626  64.011  60.638  1.00 30.49  ? 208 ASP C OD2 1 
ATOM   8767  N N   . TRP C 1 209 ? 18.141  65.878  57.586  1.00 26.72  ? 209 TRP C N   1 
ATOM   8768  C CA  . TRP C 1 209 ? 18.973  65.177  56.615  1.00 26.14  ? 209 TRP C CA  1 
ATOM   8769  C C   . TRP C 1 209 ? 18.703  63.666  56.518  1.00 23.51  ? 209 TRP C C   1 
ATOM   8770  O O   . TRP C 1 209 ? 18.410  63.177  55.433  1.00 21.43  ? 209 TRP C O   1 
ATOM   8771  C CB  . TRP C 1 209 ? 20.430  65.481  56.995  1.00 26.87  ? 209 TRP C CB  1 
ATOM   8772  C CG  . TRP C 1 209 ? 21.488  65.025  56.027  1.00 26.14  ? 209 TRP C CG  1 
ATOM   8773  C CD1 . TRP C 1 209 ? 21.792  65.585  54.827  1.00 26.39  ? 209 TRP C CD1 1 
ATOM   8774  C CD2 . TRP C 1 209 ? 22.478  64.000  56.252  1.00 27.53  ? 209 TRP C CD2 1 
ATOM   8775  N NE1 . TRP C 1 209 ? 22.853  64.938  54.261  1.00 27.37  ? 209 TRP C NE1 1 
ATOM   8776  C CE2 . TRP C 1 209 ? 23.305  63.971  55.112  1.00 27.12  ? 209 TRP C CE2 1 
ATOM   8777  C CE3 . TRP C 1 209 ? 22.745  63.099  57.289  1.00 28.37  ? 209 TRP C CE3 1 
ATOM   8778  C CZ2 . TRP C 1 209 ? 24.379  63.092  54.987  1.00 26.10  ? 209 TRP C CZ2 1 
ATOM   8779  C CZ3 . TRP C 1 209 ? 23.808  62.222  57.156  1.00 28.16  ? 209 TRP C CZ3 1 
ATOM   8780  C CH2 . TRP C 1 209 ? 24.613  62.223  56.024  1.00 25.72  ? 209 TRP C CH2 1 
ATOM   8781  N N   . SER C 1 210 ? 18.879  62.929  57.631  1.00 25.14  ? 210 SER C N   1 
ATOM   8782  C CA  . SER C 1 210 ? 18.725  61.474  57.682  1.00 26.92  ? 210 SER C CA  1 
ATOM   8783  C C   . SER C 1 210 ? 17.294  61.055  57.333  1.00 27.39  ? 210 SER C C   1 
ATOM   8784  O O   . SER C 1 210 ? 17.078  59.966  56.781  1.00 27.88  ? 210 SER C O   1 
ATOM   8785  C CB  . SER C 1 210 ? 19.038  60.863  59.085  1.00 26.20  ? 210 SER C CB  1 
ATOM   8786  O OG  . SER C 1 210 ? 20.053  61.538  59.807  1.00 26.13  ? 210 SER C OG  1 
ATOM   8787  N N   . ALA C 1 211 ? 16.316  61.841  57.814  1.00 25.65  ? 211 ALA C N   1 
ATOM   8788  C CA  . ALA C 1 211 ? 14.919  61.496  57.623  1.00 25.74  ? 211 ALA C CA  1 
ATOM   8789  C C   . ALA C 1 211 ? 14.559  61.667  56.153  1.00 25.51  ? 211 ALA C C   1 
ATOM   8790  O O   . ALA C 1 211 ? 13.885  60.801  55.579  1.00 23.41  ? 211 ALA C O   1 
ATOM   8791  C CB  . ALA C 1 211 ? 14.039  62.345  58.500  1.00 26.29  ? 211 ALA C CB  1 
ATOM   8792  N N   . ASN C 1 212 ? 15.050  62.769  55.562  1.00 24.62  ? 212 ASN C N   1 
ATOM   8793  C CA  . ASN C 1 212 ? 14.879  62.980  54.138  1.00 26.30  ? 212 ASN C CA  1 
ATOM   8794  C C   . ASN C 1 212 ? 15.441  61.806  53.350  1.00 27.94  ? 212 ASN C C   1 
ATOM   8795  O O   . ASN C 1 212 ? 14.848  61.489  52.329  1.00 24.84  ? 212 ASN C O   1 
ATOM   8796  C CB  . ASN C 1 212 ? 15.516  64.258  53.620  1.00 27.95  ? 212 ASN C CB  1 
ATOM   8797  C CG  . ASN C 1 212 ? 14.484  65.291  53.252  1.00 29.85  ? 212 ASN C CG  1 
ATOM   8798  O OD1 . ASN C 1 212 ? 13.447  64.959  52.666  1.00 31.01  ? 212 ASN C OD1 1 
ATOM   8799  N ND2 . ASN C 1 212 ? 14.751  66.543  53.588  1.00 29.12  ? 212 ASN C ND2 1 
ATOM   8800  N N   . LEU C 1 213 ? 16.580  61.213  53.783  1.00 26.78  ? 213 LEU C N   1 
ATOM   8801  C CA  . LEU C 1 213 ? 17.129  60.086  53.046  1.00 28.38  ? 213 LEU C CA  1 
ATOM   8802  C C   . LEU C 1 213 ? 16.090  58.969  53.047  1.00 31.58  ? 213 LEU C C   1 
ATOM   8803  O O   . LEU C 1 213 ? 15.905  58.262  52.051  1.00 33.64  ? 213 LEU C O   1 
ATOM   8804  C CB  . LEU C 1 213 ? 18.450  59.552  53.595  1.00 27.51  ? 213 LEU C CB  1 
ATOM   8805  C CG  . LEU C 1 213 ? 18.898  58.199  53.018  1.00 27.10  ? 213 LEU C CG  1 
ATOM   8806  C CD1 . LEU C 1 213 ? 19.052  58.220  51.508  1.00 27.48  ? 213 LEU C CD1 1 
ATOM   8807  C CD2 . LEU C 1 213 ? 20.179  57.744  53.652  1.00 27.06  ? 213 LEU C CD2 1 
ATOM   8808  N N   . ALA C 1 214 ? 15.445  58.798  54.207  1.00 33.06  ? 214 ALA C N   1 
ATOM   8809  C CA  . ALA C 1 214 ? 14.451  57.748  54.396  1.00 33.49  ? 214 ALA C CA  1 
ATOM   8810  C C   . ALA C 1 214 ? 13.200  58.037  53.566  1.00 30.37  ? 214 ALA C C   1 
ATOM   8811  O O   . ALA C 1 214 ? 12.752  57.178  52.806  1.00 26.44  ? 214 ALA C O   1 
ATOM   8812  C CB  . ALA C 1 214 ? 14.139  57.570  55.876  1.00 33.94  ? 214 ALA C CB  1 
ATOM   8813  N N   . HIS C 1 215 ? 12.671  59.262  53.706  1.00 29.31  ? 215 HIS C N   1 
ATOM   8814  C CA  . HIS C 1 215 ? 11.565  59.749  52.901  1.00 27.21  ? 215 HIS C CA  1 
ATOM   8815  C C   . HIS C 1 215 ? 11.807  59.547  51.407  1.00 25.71  ? 215 HIS C C   1 
ATOM   8816  O O   . HIS C 1 215 ? 10.902  59.134  50.698  1.00 28.44  ? 215 HIS C O   1 
ATOM   8817  C CB  . HIS C 1 215 ? 11.373  61.243  53.151  1.00 30.12  ? 215 HIS C CB  1 
ATOM   8818  C CG  . HIS C 1 215 ? 10.277  61.876  52.357  1.00 34.15  ? 215 HIS C CG  1 
ATOM   8819  N ND1 . HIS C 1 215 ? 8.948   61.553  52.528  1.00 36.76  ? 215 HIS C ND1 1 
ATOM   8820  C CD2 . HIS C 1 215 ? 10.312  62.825  51.413  1.00 34.86  ? 215 HIS C CD2 1 
ATOM   8821  C CE1 . HIS C 1 215 ? 8.210   62.292  51.709  1.00 40.25  ? 215 HIS C CE1 1 
ATOM   8822  N NE2 . HIS C 1 215 ? 9.010   63.090  51.039  1.00 38.32  ? 215 HIS C NE2 1 
ATOM   8823  N N   . MET C 1 216 ? 12.998  59.890  50.912  1.00 24.37  ? 216 MET C N   1 
ATOM   8824  C CA  . MET C 1 216 ? 13.269  59.830  49.479  1.00 24.47  ? 216 MET C CA  1 
ATOM   8825  C C   . MET C 1 216 ? 13.465  58.385  49.026  1.00 22.59  ? 216 MET C C   1 
ATOM   8826  O O   . MET C 1 216 ? 13.348  58.091  47.849  1.00 24.12  ? 216 MET C O   1 
ATOM   8827  C CB  . MET C 1 216 ? 14.484  60.688  49.099  1.00 23.68  ? 216 MET C CB  1 
ATOM   8828  C CG  . MET C 1 216 ? 14.233  62.156  49.309  1.00 24.05  ? 216 MET C CG  1 
ATOM   8829  S SD  . MET C 1 216 ? 15.492  63.208  48.573  1.00 27.14  ? 216 MET C SD  1 
ATOM   8830  C CE  . MET C 1 216 ? 16.965  62.774  49.496  1.00 30.52  ? 216 MET C CE  1 
ATOM   8831  N N   . MET C 1 217 ? 13.770  57.482  49.949  1.00 23.34  ? 217 MET C N   1 
ATOM   8832  C CA  . MET C 1 217 ? 13.842  56.064  49.617  1.00 27.89  ? 217 MET C CA  1 
ATOM   8833  C C   . MET C 1 217 ? 12.462  55.421  49.659  1.00 27.89  ? 217 MET C C   1 
ATOM   8834  O O   . MET C 1 217 ? 12.277  54.346  49.090  1.00 25.40  ? 217 MET C O   1 
ATOM   8835  C CB  . MET C 1 217 ? 14.763  55.311  50.584  1.00 29.20  ? 217 MET C CB  1 
ATOM   8836  C CG  . MET C 1 217 ? 16.218  55.693  50.430  1.00 29.34  ? 217 MET C CG  1 
ATOM   8837  S SD  . MET C 1 217 ? 17.284  54.997  51.703  1.00 29.42  ? 217 MET C SD  1 
ATOM   8838  C CE  . MET C 1 217 ? 17.063  53.229  51.513  1.00 26.10  ? 217 MET C CE  1 
ATOM   8839  N N   . GLY C 1 218 ? 11.536  56.069  50.395  1.00 32.19  ? 218 GLY C N   1 
ATOM   8840  C CA  . GLY C 1 218 ? 10.135  55.674  50.461  1.00 33.36  ? 218 GLY C CA  1 
ATOM   8841  C C   . GLY C 1 218 ? 9.691   55.149  51.833  1.00 33.33  ? 218 GLY C C   1 
ATOM   8842  O O   . GLY C 1 218 ? 8.677   54.465  51.901  1.00 34.41  ? 218 GLY C O   1 
ATOM   8843  N N   . PHE C 1 219 ? 10.414  55.473  52.914  1.00 31.06  ? 219 PHE C N   1 
ATOM   8844  C CA  . PHE C 1 219 ? 10.050  55.052  54.267  1.00 30.03  ? 219 PHE C CA  1 
ATOM   8845  C C   . PHE C 1 219 ? 9.734   56.289  55.101  1.00 28.86  ? 219 PHE C C   1 
ATOM   8846  O O   . PHE C 1 219 ? 10.584  57.163  55.207  1.00 27.71  ? 219 PHE C O   1 
ATOM   8847  C CB  . PHE C 1 219 ? 11.201  54.293  54.935  1.00 29.96  ? 219 PHE C CB  1 
ATOM   8848  C CG  . PHE C 1 219 ? 11.567  53.049  54.145  1.00 31.09  ? 219 PHE C CG  1 
ATOM   8849  C CD1 . PHE C 1 219 ? 12.472  53.121  53.089  1.00 31.21  ? 219 PHE C CD1 1 
ATOM   8850  C CD2 . PHE C 1 219 ? 10.959  51.838  54.415  1.00 29.33  ? 219 PHE C CD2 1 
ATOM   8851  C CE1 . PHE C 1 219 ? 12.799  52.000  52.356  1.00 31.04  ? 219 PHE C CE1 1 
ATOM   8852  C CE2 . PHE C 1 219 ? 11.262  50.720  53.661  1.00 35.08  ? 219 PHE C CE2 1 
ATOM   8853  C CZ  . PHE C 1 219 ? 12.195  50.796  52.639  1.00 36.19  ? 219 PHE C CZ  1 
ATOM   8854  N N   . ASP C 1 220 ? 8.531   56.351  55.701  1.00 30.92  ? 220 ASP C N   1 
ATOM   8855  C CA  . ASP C 1 220 ? 8.090   57.553  56.411  1.00 33.99  ? 220 ASP C CA  1 
ATOM   8856  C C   . ASP C 1 220 ? 7.727   57.321  57.890  1.00 33.45  ? 220 ASP C C   1 
ATOM   8857  O O   . ASP C 1 220 ? 7.507   58.287  58.614  1.00 33.54  ? 220 ASP C O   1 
ATOM   8858  C CB  . ASP C 1 220 ? 6.991   58.270  55.637  1.00 33.87  ? 220 ASP C CB  1 
ATOM   8859  C CG  . ASP C 1 220 ? 7.477   59.000  54.390  1.00 35.31  ? 220 ASP C CG  1 
ATOM   8860  O OD1 . ASP C 1 220 ? 8.387   59.851  54.524  1.00 34.61  ? 220 ASP C OD1 1 
ATOM   8861  O OD2 . ASP C 1 220 ? 6.950   58.708  53.301  1.00 32.74  ? 220 ASP C OD2 1 
ATOM   8862  N N   . ASP C 1 221 ? 7.676   56.076  58.374  1.00 35.37  ? 221 ASP C N   1 
ATOM   8863  C CA  . ASP C 1 221 ? 7.525   55.820  59.800  1.00 37.42  ? 221 ASP C CA  1 
ATOM   8864  C C   . ASP C 1 221 ? 8.545   56.573  60.656  1.00 40.21  ? 221 ASP C C   1 
ATOM   8865  O O   . ASP C 1 221 ? 9.753   56.626  60.378  1.00 36.18  ? 221 ASP C O   1 
ATOM   8866  C CB  . ASP C 1 221 ? 7.727   54.356  60.131  1.00 43.50  ? 221 ASP C CB  1 
ATOM   8867  C CG  . ASP C 1 221 ? 6.581   53.460  59.700  1.00 49.93  ? 221 ASP C CG  1 
ATOM   8868  O OD1 . ASP C 1 221 ? 5.805   53.884  58.812  1.00 51.43  ? 221 ASP C OD1 1 
ATOM   8869  O OD2 . ASP C 1 221 ? 6.452   52.383  60.298  1.00 59.39  ? 221 ASP C OD2 1 
ATOM   8870  N N   . PHE C 1 222 ? 8.032   57.106  61.758  1.00 41.90  ? 222 PHE C N   1 
ATOM   8871  C CA  . PHE C 1 222 ? 8.855   57.744  62.764  1.00 39.90  ? 222 PHE C CA  1 
ATOM   8872  C C   . PHE C 1 222 ? 10.045  56.870  63.160  1.00 38.92  ? 222 PHE C C   1 
ATOM   8873  O O   . PHE C 1 222 ? 11.136  57.399  63.338  1.00 43.28  ? 222 PHE C O   1 
ATOM   8874  C CB  . PHE C 1 222 ? 7.961   58.029  63.970  1.00 36.62  ? 222 PHE C CB  1 
ATOM   8875  C CG  . PHE C 1 222 ? 8.722   58.608  65.153  1.00 38.81  ? 222 PHE C CG  1 
ATOM   8876  C CD1 . PHE C 1 222 ? 9.206   59.915  65.108  1.00 37.74  ? 222 PHE C CD1 1 
ATOM   8877  C CD2 . PHE C 1 222 ? 8.925   57.854  66.315  1.00 39.18  ? 222 PHE C CD2 1 
ATOM   8878  C CE1 . PHE C 1 222 ? 9.882   60.456  66.193  1.00 39.58  ? 222 PHE C CE1 1 
ATOM   8879  C CE2 . PHE C 1 222 ? 9.606   58.398  67.402  1.00 37.48  ? 222 PHE C CE2 1 
ATOM   8880  C CZ  . PHE C 1 222 ? 10.091  59.696  67.334  1.00 39.64  ? 222 PHE C CZ  1 
ATOM   8881  N N   . GLU C 1 223 ? 9.829   55.559  63.356  1.00 39.15  ? 223 GLU C N   1 
ATOM   8882  C CA  . GLU C 1 223 ? 10.868  54.669  63.865  1.00 40.10  ? 223 GLU C CA  1 
ATOM   8883  C C   . GLU C 1 223 ? 12.028  54.595  62.869  1.00 39.15  ? 223 GLU C C   1 
ATOM   8884  O O   . GLU C 1 223 ? 13.186  54.549  63.280  1.00 33.84  ? 223 GLU C O   1 
ATOM   8885  C CB  . GLU C 1 223 ? 10.359  53.247  64.114  1.00 48.77  ? 223 GLU C CB  1 
ATOM   8886  C CG  . GLU C 1 223 ? 9.550   53.038  65.401  1.00 56.89  ? 223 GLU C CG  1 
ATOM   8887  C CD  . GLU C 1 223 ? 8.833   51.686  65.549  1.00 58.44  ? 223 GLU C CD  1 
ATOM   8888  O OE1 . GLU C 1 223 ? 7.592   51.699  65.669  1.00 64.55  ? 223 GLU C OE1 1 
ATOM   8889  O OE2 . GLU C 1 223 ? 9.473   50.608  65.550  1.00 58.91  ? 223 GLU C OE2 1 
ATOM   8890  N N   . VAL C 1 224 ? 11.704  54.562  61.563  1.00 34.95  ? 224 VAL C N   1 
ATOM   8891  C CA  . VAL C 1 224 ? 12.702  54.503  60.510  1.00 32.32  ? 224 VAL C CA  1 
ATOM   8892  C C   . VAL C 1 224 ? 13.511  55.799  60.475  1.00 29.64  ? 224 VAL C C   1 
ATOM   8893  O O   . VAL C 1 224 ? 14.731  55.747  60.403  1.00 30.62  ? 224 VAL C O   1 
ATOM   8894  C CB  . VAL C 1 224 ? 12.107  54.174  59.135  1.00 34.60  ? 224 VAL C CB  1 
ATOM   8895  C CG1 . VAL C 1 224 ? 13.176  54.222  58.058  1.00 36.96  ? 224 VAL C CG1 1 
ATOM   8896  C CG2 . VAL C 1 224 ? 11.439  52.799  59.137  1.00 36.85  ? 224 VAL C CG2 1 
ATOM   8897  N N   . TYR C 1 225 ? 12.860  56.954  60.592  1.00 26.01  ? 225 TYR C N   1 
ATOM   8898  C CA  . TYR C 1 225 ? 13.595  58.194  60.725  1.00 27.79  ? 225 TYR C CA  1 
ATOM   8899  C C   . TYR C 1 225 ? 14.567  58.087  61.904  1.00 32.06  ? 225 TYR C C   1 
ATOM   8900  O O   . TYR C 1 225 ? 15.752  58.468  61.810  1.00 34.94  ? 225 TYR C O   1 
ATOM   8901  C CB  . TYR C 1 225 ? 12.678  59.417  60.876  1.00 29.77  ? 225 TYR C CB  1 
ATOM   8902  C CG  . TYR C 1 225 ? 11.750  59.797  59.722  1.00 28.38  ? 225 TYR C CG  1 
ATOM   8903  C CD1 . TYR C 1 225 ? 11.856  59.221  58.462  1.00 32.56  ? 225 TYR C CD1 1 
ATOM   8904  C CD2 . TYR C 1 225 ? 10.759  60.756  59.905  1.00 30.38  ? 225 TYR C CD2 1 
ATOM   8905  C CE1 . TYR C 1 225 ? 10.998  59.584  57.428  1.00 35.34  ? 225 TYR C CE1 1 
ATOM   8906  C CE2 . TYR C 1 225 ? 9.901   61.137  58.883  1.00 30.38  ? 225 TYR C CE2 1 
ATOM   8907  C CZ  . TYR C 1 225 ? 10.023  60.555  57.632  1.00 34.28  ? 225 TYR C CZ  1 
ATOM   8908  O OH  . TYR C 1 225 ? 9.160   60.900  56.618  1.00 33.95  ? 225 TYR C OH  1 
ATOM   8909  N N   . GLU C 1 226 ? 14.071  57.567  63.036  1.00 27.67  ? 226 GLU C N   1 
ATOM   8910  C CA  . GLU C 1 226 ? 14.910  57.476  64.218  1.00 25.09  ? 226 GLU C CA  1 
ATOM   8911  C C   . GLU C 1 226 ? 16.082  56.530  63.964  1.00 25.66  ? 226 GLU C C   1 
ATOM   8912  O O   . GLU C 1 226 ? 17.205  56.824  64.374  1.00 26.13  ? 226 GLU C O   1 
ATOM   8913  C CB  . GLU C 1 226 ? 14.107  57.090  65.457  1.00 25.10  ? 226 GLU C CB  1 
ATOM   8914  C CG  . GLU C 1 226 ? 13.222  58.238  65.926  1.00 25.48  ? 226 GLU C CG  1 
ATOM   8915  C CD  . GLU C 1 226 ? 13.928  59.289  66.746  1.00 26.71  ? 226 GLU C CD  1 
ATOM   8916  O OE1 . GLU C 1 226 ? 14.427  60.310  66.211  1.00 24.45  ? 226 GLU C OE1 1 
ATOM   8917  O OE2 . GLU C 1 226 ? 13.954  59.041  67.978  1.00 29.68  ? 226 GLU C OE2 1 
ATOM   8918  N N   . LEU C 1 227 ? 15.821  55.397  63.305  1.00 24.98  ? 227 LEU C N   1 
ATOM   8919  C CA  . LEU C 1 227 ? 16.866  54.454  62.946  1.00 26.38  ? 227 LEU C CA  1 
ATOM   8920  C C   . LEU C 1 227 ? 17.894  55.144  62.054  1.00 25.17  ? 227 LEU C C   1 
ATOM   8921  O O   . LEU C 1 227 ? 19.098  55.060  62.277  1.00 24.89  ? 227 LEU C O   1 
ATOM   8922  C CB  . LEU C 1 227 ? 16.274  53.226  62.259  1.00 28.46  ? 227 LEU C CB  1 
ATOM   8923  C CG  . LEU C 1 227 ? 17.283  52.300  61.581  1.00 29.76  ? 227 LEU C CG  1 
ATOM   8924  C CD1 . LEU C 1 227 ? 18.257  51.841  62.618  1.00 33.86  ? 227 LEU C CD1 1 
ATOM   8925  C CD2 . LEU C 1 227 ? 16.653  51.115  60.889  1.00 29.58  ? 227 LEU C CD2 1 
ATOM   8926  N N   . PHE C 1 228 ? 17.411  55.864  61.057  1.00 25.03  ? 228 PHE C N   1 
ATOM   8927  C CA  . PHE C 1 228 ? 18.329  56.469  60.120  1.00 25.60  ? 228 PHE C CA  1 
ATOM   8928  C C   . PHE C 1 228 ? 19.231  57.438  60.874  1.00 27.06  ? 228 PHE C C   1 
ATOM   8929  O O   . PHE C 1 228 ? 20.445  57.428  60.651  1.00 25.65  ? 228 PHE C O   1 
ATOM   8930  C CB  . PHE C 1 228 ? 17.606  57.077  58.919  1.00 24.57  ? 228 PHE C CB  1 
ATOM   8931  C CG  . PHE C 1 228 ? 17.399  56.047  57.814  1.00 26.06  ? 228 PHE C CG  1 
ATOM   8932  C CD1 . PHE C 1 228 ? 16.918  54.778  58.099  1.00 28.08  ? 228 PHE C CD1 1 
ATOM   8933  C CD2 . PHE C 1 228 ? 17.744  56.338  56.499  1.00 27.55  ? 228 PHE C CD2 1 
ATOM   8934  C CE1 . PHE C 1 228 ? 16.727  53.856  57.082  1.00 32.10  ? 228 PHE C CE1 1 
ATOM   8935  C CE2 . PHE C 1 228 ? 17.558  55.417  55.484  1.00 27.58  ? 228 PHE C CE2 1 
ATOM   8936  C CZ  . PHE C 1 228 ? 17.052  54.181  55.774  1.00 31.76  ? 228 PHE C CZ  1 
ATOM   8937  N N   . ARG C 1 229 ? 18.641  58.242  61.766  1.00 27.28  ? 229 ARG C N   1 
ATOM   8938  C CA  . ARG C 1 229 ? 19.408  59.233  62.504  1.00 27.53  ? 229 ARG C CA  1 
ATOM   8939  C C   . ARG C 1 229 ? 20.504  58.552  63.318  1.00 28.31  ? 229 ARG C C   1 
ATOM   8940  O O   . ARG C 1 229 ? 21.642  59.027  63.333  1.00 27.64  ? 229 ARG C O   1 
ATOM   8941  C CB  . ARG C 1 229 ? 18.469  60.062  63.382  1.00 30.26  ? 229 ARG C CB  1 
ATOM   8942  C CG  . ARG C 1 229 ? 17.482  60.931  62.607  1.00 31.25  ? 229 ARG C CG  1 
ATOM   8943  C CD  . ARG C 1 229 ? 16.296  61.308  63.469  1.00 31.78  ? 229 ARG C CD  1 
ATOM   8944  N NE  . ARG C 1 229 ? 15.376  62.217  62.789  1.00 33.90  ? 229 ARG C NE  1 
ATOM   8945  C CZ  . ARG C 1 229 ? 14.058  62.184  62.878  1.00 32.34  ? 229 ARG C CZ  1 
ATOM   8946  N NH1 . ARG C 1 229 ? 13.469  61.359  63.694  1.00 35.59  ? 229 ARG C NH1 1 
ATOM   8947  N NH2 . ARG C 1 229 ? 13.316  63.007  62.185  1.00 32.85  ? 229 ARG C NH2 1 
ATOM   8948  N N   . LEU C 1 230 ? 20.151  57.459  64.015  1.00 29.69  ? 230 LEU C N   1 
ATOM   8949  C CA  . LEU C 1 230 ? 21.101  56.762  64.875  1.00 31.01  ? 230 LEU C CA  1 
ATOM   8950  C C   . LEU C 1 230 ? 22.221  56.186  64.005  1.00 30.27  ? 230 LEU C C   1 
ATOM   8951  O O   . LEU C 1 230 ? 23.400  56.365  64.305  1.00 27.26  ? 230 LEU C O   1 
ATOM   8952  C CB  . LEU C 1 230 ? 20.416  55.643  65.666  1.00 30.43  ? 230 LEU C CB  1 
ATOM   8953  C CG  . LEU C 1 230 ? 21.326  54.811  66.579  1.00 30.63  ? 230 LEU C CG  1 
ATOM   8954  C CD1 . LEU C 1 230 ? 22.103  55.692  67.563  1.00 29.10  ? 230 LEU C CD1 1 
ATOM   8955  C CD2 . LEU C 1 230 ? 20.558  53.763  67.343  1.00 29.58  ? 230 LEU C CD2 1 
ATOM   8956  N N   . TYR C 1 231 ? 21.807  55.478  62.940  1.00 30.79  ? 231 TYR C N   1 
ATOM   8957  C CA  . TYR C 1 231 ? 22.708  54.841  61.987  1.00 30.35  ? 231 TYR C CA  1 
ATOM   8958  C C   . TYR C 1 231 ? 23.776  55.834  61.549  1.00 28.76  ? 231 TYR C C   1 
ATOM   8959  O O   . TYR C 1 231 ? 24.963  55.525  61.606  1.00 28.31  ? 231 TYR C O   1 
ATOM   8960  C CB  . TYR C 1 231 ? 21.998  54.270  60.760  1.00 28.75  ? 231 TYR C CB  1 
ATOM   8961  C CG  . TYR C 1 231 ? 22.903  53.516  59.787  1.00 33.69  ? 231 TYR C CG  1 
ATOM   8962  C CD1 . TYR C 1 231 ? 23.686  54.185  58.849  1.00 36.15  ? 231 TYR C CD1 1 
ATOM   8963  C CD2 . TYR C 1 231 ? 22.924  52.130  59.750  1.00 34.71  ? 231 TYR C CD2 1 
ATOM   8964  C CE1 . TYR C 1 231 ? 24.480  53.498  57.943  1.00 37.25  ? 231 TYR C CE1 1 
ATOM   8965  C CE2 . TYR C 1 231 ? 23.701  51.428  58.843  1.00 36.71  ? 231 TYR C CE2 1 
ATOM   8966  C CZ  . TYR C 1 231 ? 24.497  52.108  57.934  1.00 42.87  ? 231 TYR C CZ  1 
ATOM   8967  O OH  . TYR C 1 231 ? 25.292  51.387  57.043  1.00 41.36  ? 231 TYR C OH  1 
ATOM   8968  N N   . MET C 1 232 ? 23.337  57.031  61.170  1.00 29.19  ? 232 MET C N   1 
ATOM   8969  C CA  . MET C 1 232 ? 24.203  58.025  60.570  1.00 29.82  ? 232 MET C CA  1 
ATOM   8970  C C   . MET C 1 232 ? 25.152  58.573  61.627  1.00 30.68  ? 232 MET C C   1 
ATOM   8971  O O   . MET C 1 232 ? 26.319  58.840  61.352  1.00 30.66  ? 232 MET C O   1 
ATOM   8972  C CB  . MET C 1 232 ? 23.370  59.136  59.922  1.00 31.82  ? 232 MET C CB  1 
ATOM   8973  C CG  . MET C 1 232 ? 22.578  58.664  58.699  1.00 37.20  ? 232 MET C CG  1 
ATOM   8974  S SD  . MET C 1 232 ? 23.582  58.284  57.243  1.00 34.24  ? 232 MET C SD  1 
ATOM   8975  C CE  . MET C 1 232 ? 22.734  56.839  56.608  1.00 37.43  ? 232 MET C CE  1 
ATOM   8976  N N   . PHE C 1 233 ? 24.652  58.693  62.856  1.00 33.09  ? 233 PHE C N   1 
ATOM   8977  C CA  . PHE C 1 233 ? 25.485  59.100  63.976  1.00 29.76  ? 233 PHE C CA  1 
ATOM   8978  C C   . PHE C 1 233 ? 26.614  58.094  64.235  1.00 29.69  ? 233 PHE C C   1 
ATOM   8979  O O   . PHE C 1 233 ? 27.796  58.447  64.273  1.00 26.11  ? 233 PHE C O   1 
ATOM   8980  C CB  . PHE C 1 233 ? 24.471  59.276  65.097  1.00 27.31  ? 233 PHE C CB  1 
ATOM   8981  C CG  . PHE C 1 233 ? 25.106  59.333  66.471  1.00 31.07  ? 233 PHE C CG  1 
ATOM   8982  C CD1 . PHE C 1 233 ? 25.691  60.504  66.924  1.00 30.93  ? 233 PHE C CD1 1 
ATOM   8983  C CD2 . PHE C 1 233 ? 25.115  58.206  67.303  1.00 30.97  ? 233 PHE C CD2 1 
ATOM   8984  C CE1 . PHE C 1 233 ? 26.245  60.559  68.195  1.00 30.29  ? 233 PHE C CE1 1 
ATOM   8985  C CE2 . PHE C 1 233 ? 25.659  58.269  68.570  1.00 29.36  ? 233 PHE C CE2 1 
ATOM   8986  C CZ  . PHE C 1 233 ? 26.229  59.445  69.012  1.00 29.93  ? 233 PHE C CZ  1 
ATOM   8987  N N   . LEU C 1 234 ? 26.233  56.831  64.425  1.00 31.16  ? 234 LEU C N   1 
ATOM   8988  C CA  . LEU C 1 234 ? 27.159  55.785  64.829  1.00 31.67  ? 234 LEU C CA  1 
ATOM   8989  C C   . LEU C 1 234 ? 28.242  55.522  63.784  1.00 31.82  ? 234 LEU C C   1 
ATOM   8990  O O   . LEU C 1 234 ? 29.362  55.153  64.116  1.00 31.13  ? 234 LEU C O   1 
ATOM   8991  C CB  . LEU C 1 234 ? 26.333  54.518  65.014  1.00 32.81  ? 234 LEU C CB  1 
ATOM   8992  C CG  . LEU C 1 234 ? 25.359  54.512  66.185  1.00 31.31  ? 234 LEU C CG  1 
ATOM   8993  C CD1 . LEU C 1 234 ? 24.710  53.153  66.200  1.00 31.30  ? 234 LEU C CD1 1 
ATOM   8994  C CD2 . LEU C 1 234 ? 26.060  54.845  67.487  1.00 30.15  ? 234 LEU C CD2 1 
ATOM   8995  N N   . HIS C 1 235 ? 27.893  55.623  62.507  1.00 31.50  ? 235 HIS C N   1 
ATOM   8996  C CA  . HIS C 1 235 ? 28.823  55.205  61.481  1.00 30.04  ? 235 HIS C CA  1 
ATOM   8997  C C   . HIS C 1 235 ? 29.602  56.387  60.925  1.00 28.79  ? 235 HIS C C   1 
ATOM   8998  O O   . HIS C 1 235 ? 30.282  56.262  59.933  1.00 29.51  ? 235 HIS C O   1 
ATOM   8999  C CB  . HIS C 1 235 ? 28.076  54.466  60.383  1.00 28.02  ? 235 HIS C CB  1 
ATOM   9000  C CG  . HIS C 1 235 ? 27.506  53.149  60.775  1.00 27.20  ? 235 HIS C CG  1 
ATOM   9001  N ND1 . HIS C 1 235 ? 26.208  53.016  61.207  1.00 30.94  ? 235 HIS C ND1 1 
ATOM   9002  C CD2 . HIS C 1 235 ? 27.995  51.887  60.665  1.00 26.53  ? 235 HIS C CD2 1 
ATOM   9003  C CE1 . HIS C 1 235 ? 25.940  51.711  61.369  1.00 29.96  ? 235 HIS C CE1 1 
ATOM   9004  N NE2 . HIS C 1 235 ? 27.014  51.013  61.041  1.00 26.96  ? 235 HIS C NE2 1 
ATOM   9005  N N   . SER C 1 236 ? 29.540  57.535  61.576  1.00 30.51  ? 236 SER C N   1 
ATOM   9006  C CA  . SER C 1 236 ? 29.979  58.758  60.926  1.00 32.08  ? 236 SER C CA  1 
ATOM   9007  C C   . SER C 1 236 ? 31.495  58.784  60.709  1.00 34.85  ? 236 SER C C   1 
ATOM   9008  O O   . SER C 1 236 ? 31.983  59.476  59.817  1.00 34.76  ? 236 SER C O   1 
ATOM   9009  C CB  . SER C 1 236 ? 29.529  59.953  61.745  1.00 31.60  ? 236 SER C CB  1 
ATOM   9010  O OG  . SER C 1 236 ? 29.985  59.836  63.089  1.00 30.90  ? 236 SER C OG  1 
ATOM   9011  N N   . ASP C 1 237 ? 32.254  58.111  61.586  1.00 37.56  ? 237 ASP C N   1 
ATOM   9012  C CA  . ASP C 1 237 ? 33.691  58.320  61.677  1.00 32.55  ? 237 ASP C CA  1 
ATOM   9013  C C   . ASP C 1 237 ? 34.283  57.239  62.579  1.00 31.31  ? 237 ASP C C   1 
ATOM   9014  O O   . ASP C 1 237 ? 33.607  56.716  63.464  1.00 32.13  ? 237 ASP C O   1 
ATOM   9015  C CB  . ASP C 1 237 ? 33.994  59.735  62.153  1.00 32.78  ? 237 ASP C CB  1 
ATOM   9016  C CG  . ASP C 1 237 ? 35.374  60.309  61.865  1.00 31.49  ? 237 ASP C CG  1 
ATOM   9017  O OD1 . ASP C 1 237 ? 35.757  60.313  60.692  1.00 35.67  ? 237 ASP C OD1 1 
ATOM   9018  O OD2 . ASP C 1 237 ? 36.043  60.792  62.806  1.00 31.07  ? 237 ASP C OD2 1 
ATOM   9019  N N   . HIS C 1 238 ? 35.555  56.905  62.321  1.00 31.75  ? 238 HIS C N   1 
ATOM   9020  C CA  . HIS C 1 238 ? 36.297  55.885  63.052  1.00 31.28  ? 238 HIS C CA  1 
ATOM   9021  C C   . HIS C 1 238 ? 37.784  56.029  62.741  1.00 30.75  ? 238 HIS C C   1 
ATOM   9022  O O   . HIS C 1 238 ? 38.384  55.182  62.098  1.00 31.79  ? 238 HIS C O   1 
ATOM   9023  C CB  . HIS C 1 238 ? 35.782  54.481  62.730  1.00 32.23  ? 238 HIS C CB  1 
ATOM   9024  C CG  . HIS C 1 238 ? 36.265  53.441  63.684  1.00 41.07  ? 238 HIS C CG  1 
ATOM   9025  N ND1 . HIS C 1 238 ? 37.131  52.418  63.357  1.00 43.10  ? 238 HIS C ND1 1 
ATOM   9026  C CD2 . HIS C 1 238 ? 35.952  53.273  64.983  1.00 44.88  ? 238 HIS C CD2 1 
ATOM   9027  C CE1 . HIS C 1 238 ? 37.352  51.682  64.433  1.00 44.96  ? 238 HIS C CE1 1 
ATOM   9028  N NE2 . HIS C 1 238 ? 36.636  52.177  65.432  1.00 46.12  ? 238 HIS C NE2 1 
ATOM   9029  N N   . GLU C 1 239 ? 38.383  57.133  63.188  1.00 33.94  ? 239 GLU C N   1 
ATOM   9030  C CA  . GLU C 1 239 ? 39.787  57.406  62.930  1.00 38.92  ? 239 GLU C CA  1 
ATOM   9031  C C   . GLU C 1 239 ? 39.990  57.623  61.431  1.00 39.39  ? 239 GLU C C   1 
ATOM   9032  O O   . GLU C 1 239 ? 39.015  57.712  60.680  1.00 32.25  ? 239 GLU C O   1 
ATOM   9033  C CB  . GLU C 1 239 ? 40.654  56.320  63.584  1.00 40.58  ? 239 GLU C CB  1 
ATOM   9034  C CG  . GLU C 1 239 ? 41.068  56.702  65.005  1.00 41.27  ? 239 GLU C CG  1 
ATOM   9035  C CD  . GLU C 1 239 ? 41.957  55.692  65.723  1.00 44.56  ? 239 GLU C CD  1 
ATOM   9036  O OE1 . GLU C 1 239 ? 42.410  56.070  66.824  1.00 43.06  ? 239 GLU C OE1 1 
ATOM   9037  O OE2 . GLU C 1 239 ? 42.153  54.547  65.250  1.00 36.78  ? 239 GLU C OE2 1 
ATOM   9038  N N   . GLY C 1 240 ? 41.268  57.724  61.027  1.00 39.49  ? 240 GLY C N   1 
ATOM   9039  C CA  . GLY C 1 240 ? 41.631  58.100  59.671  1.00 37.95  ? 240 GLY C CA  1 
ATOM   9040  C C   . GLY C 1 240 ? 42.395  57.009  58.932  1.00 36.52  ? 240 GLY C C   1 
ATOM   9041  O O   . GLY C 1 240 ? 42.803  57.221  57.798  1.00 40.09  ? 240 GLY C O   1 
ATOM   9042  N N   . GLY C 1 241 ? 42.564  55.842  59.551  1.00 33.50  ? 241 GLY C N   1 
ATOM   9043  C CA  . GLY C 1 241 ? 43.442  54.819  59.006  1.00 30.46  ? 241 GLY C CA  1 
ATOM   9044  C C   . GLY C 1 241 ? 42.706  53.768  58.180  1.00 28.77  ? 241 GLY C C   1 
ATOM   9045  O O   . GLY C 1 241 ? 43.324  53.073  57.370  1.00 28.44  ? 241 GLY C O   1 
ATOM   9046  N N   . ASN C 1 242 ? 41.388  53.650  58.353  1.00 27.63  ? 242 ASN C N   1 
ATOM   9047  C CA  . ASN C 1 242 ? 40.610  52.766  57.488  1.00 29.05  ? 242 ASN C CA  1 
ATOM   9048  C C   . ASN C 1 242 ? 40.749  53.199  56.014  1.00 28.91  ? 242 ASN C C   1 
ATOM   9049  O O   . ASN C 1 242 ? 41.054  54.361  55.704  1.00 27.82  ? 242 ASN C O   1 
ATOM   9050  C CB  . ASN C 1 242 ? 39.162  52.683  57.962  1.00 28.28  ? 242 ASN C CB  1 
ATOM   9051  C CG  . ASN C 1 242 ? 38.469  54.021  57.881  1.00 32.06  ? 242 ASN C CG  1 
ATOM   9052  O OD1 . ASN C 1 242 ? 38.218  54.532  56.780  1.00 34.54  ? 242 ASN C OD1 1 
ATOM   9053  N ND2 . ASN C 1 242 ? 38.143  54.607  59.024  1.00 33.51  ? 242 ASN C ND2 1 
ATOM   9054  N N   . VAL C 1 243 ? 40.534  52.260  55.082  1.00 29.02  ? 243 VAL C N   1 
ATOM   9055  C CA  . VAL C 1 243 ? 40.847  52.510  53.681  1.00 30.81  ? 243 VAL C CA  1 
ATOM   9056  C C   . VAL C 1 243 ? 40.108  53.752  53.167  1.00 30.56  ? 243 VAL C C   1 
ATOM   9057  O O   . VAL C 1 243 ? 40.715  54.644  52.574  1.00 31.86  ? 243 VAL C O   1 
ATOM   9058  C CB  . VAL C 1 243 ? 40.564  51.297  52.788  1.00 34.46  ? 243 VAL C CB  1 
ATOM   9059  C CG1 . VAL C 1 243 ? 40.737  51.636  51.298  1.00 35.94  ? 243 VAL C CG1 1 
ATOM   9060  C CG2 . VAL C 1 243 ? 41.429  50.093  53.181  1.00 36.03  ? 243 VAL C CG2 1 
ATOM   9061  N N   . SER C 1 244 ? 38.805  53.835  53.421  1.00 29.57  ? 244 SER C N   1 
ATOM   9062  C CA  . SER C 1 244 ? 37.986  54.921  52.904  1.00 27.71  ? 244 SER C CA  1 
ATOM   9063  C C   . SER C 1 244 ? 38.404  56.260  53.486  1.00 24.89  ? 244 SER C C   1 
ATOM   9064  O O   . SER C 1 244 ? 38.473  57.225  52.754  1.00 23.70  ? 244 SER C O   1 
ATOM   9065  C CB  . SER C 1 244 ? 36.507  54.678  53.134  1.00 28.17  ? 244 SER C CB  1 
ATOM   9066  O OG  . SER C 1 244 ? 36.137  54.863  54.489  1.00 32.43  ? 244 SER C OG  1 
ATOM   9067  N N   . ALA C 1 245 ? 38.665  56.331  54.793  1.00 27.13  ? 245 ALA C N   1 
ATOM   9068  C CA  . ALA C 1 245 ? 39.057  57.593  55.412  1.00 29.36  ? 245 ALA C CA  1 
ATOM   9069  C C   . ALA C 1 245 ? 40.443  57.998  54.917  1.00 27.83  ? 245 ALA C C   1 
ATOM   9070  O O   . ALA C 1 245 ? 40.696  59.171  54.653  1.00 27.97  ? 245 ALA C O   1 
ATOM   9071  C CB  . ALA C 1 245 ? 39.000  57.498  56.932  1.00 29.69  ? 245 ALA C CB  1 
ATOM   9072  N N   . HIS C 1 246 ? 41.327  56.999  54.781  1.00 29.74  ? 246 HIS C N   1 
ATOM   9073  C CA  . HIS C 1 246 ? 42.699  57.211  54.309  1.00 29.90  ? 246 HIS C CA  1 
ATOM   9074  C C   . HIS C 1 246 ? 42.703  57.707  52.858  1.00 25.82  ? 246 HIS C C   1 
ATOM   9075  O O   . HIS C 1 246 ? 43.392  58.682  52.544  1.00 28.13  ? 246 HIS C O   1 
ATOM   9076  C CB  . HIS C 1 246 ? 43.561  55.945  54.491  1.00 26.92  ? 246 HIS C CB  1 
ATOM   9077  C CG  . HIS C 1 246 ? 45.006  56.151  54.170  1.00 25.96  ? 246 HIS C CG  1 
ATOM   9078  N ND1 . HIS C 1 246 ? 45.887  55.091  54.108  1.00 23.20  ? 246 HIS C ND1 1 
ATOM   9079  C CD2 . HIS C 1 246 ? 45.755  57.286  53.966  1.00 26.60  ? 246 HIS C CD2 1 
ATOM   9080  C CE1 . HIS C 1 246 ? 47.108  55.568  53.834  1.00 25.21  ? 246 HIS C CE1 1 
ATOM   9081  N NE2 . HIS C 1 246 ? 47.054  56.901  53.745  1.00 24.70  ? 246 HIS C NE2 1 
ATOM   9082  N N   . THR C 1 247 ? 41.928  57.042  51.992  1.00 22.24  ? 247 THR C N   1 
ATOM   9083  C CA  . THR C 1 247 ? 41.871  57.398  50.581  1.00 22.87  ? 247 THR C CA  1 
ATOM   9084  C C   . THR C 1 247 ? 41.468  58.857  50.470  1.00 24.69  ? 247 THR C C   1 
ATOM   9085  O O   . THR C 1 247 ? 42.104  59.632  49.763  1.00 22.51  ? 247 THR C O   1 
ATOM   9086  C CB  . THR C 1 247 ? 40.879  56.520  49.841  1.00 22.82  ? 247 THR C CB  1 
ATOM   9087  O OG1 . THR C 1 247 ? 41.337  55.171  49.901  1.00 21.69  ? 247 THR C OG1 1 
ATOM   9088  C CG2 . THR C 1 247 ? 40.708  56.974  48.411  1.00 24.25  ? 247 THR C CG2 1 
ATOM   9089  N N   . ASN C 1 248 ? 40.448  59.218  51.256  1.00 28.35  ? 248 ASN C N   1 
ATOM   9090  C CA  . ASN C 1 248 ? 39.968  60.586  51.325  1.00 28.39  ? 248 ASN C CA  1 
ATOM   9091  C C   . ASN C 1 248 ? 41.128  61.525  51.637  1.00 30.01  ? 248 ASN C C   1 
ATOM   9092  O O   . ASN C 1 248 ? 41.342  62.502  50.937  1.00 32.19  ? 248 ASN C O   1 
ATOM   9093  C CB  . ASN C 1 248 ? 38.805  60.708  52.304  1.00 29.73  ? 248 ASN C CB  1 
ATOM   9094  C CG  . ASN C 1 248 ? 38.294  62.128  52.427  1.00 29.50  ? 248 ASN C CG  1 
ATOM   9095  O OD1 . ASN C 1 248 ? 38.328  62.710  53.524  1.00 30.84  ? 248 ASN C OD1 1 
ATOM   9096  N ND2 . ASN C 1 248 ? 37.852  62.710  51.325  1.00 24.27  ? 248 ASN C ND2 1 
ATOM   9097  N N   . LEU C 1 249 ? 41.894  61.245  52.686  1.00 33.84  ? 249 LEU C N   1 
ATOM   9098  C CA  . LEU C 1 249 ? 42.968  62.153  53.074  1.00 33.89  ? 249 LEU C CA  1 
ATOM   9099  C C   . LEU C 1 249 ? 44.052  62.224  51.992  1.00 31.21  ? 249 LEU C C   1 
ATOM   9100  O O   . LEU C 1 249 ? 44.554  63.312  51.675  1.00 25.12  ? 249 LEU C O   1 
ATOM   9101  C CB  . LEU C 1 249 ? 43.542  61.714  54.418  1.00 36.91  ? 249 LEU C CB  1 
ATOM   9102  C CG  . LEU C 1 249 ? 42.695  62.045  55.647  1.00 36.62  ? 249 LEU C CG  1 
ATOM   9103  C CD1 . LEU C 1 249 ? 43.360  61.425  56.852  1.00 36.41  ? 249 LEU C CD1 1 
ATOM   9104  C CD2 . LEU C 1 249 ? 42.538  63.544  55.824  1.00 37.37  ? 249 LEU C CD2 1 
ATOM   9105  N N   . LEU C 1 250 ? 44.407  61.045  51.453  1.00 28.66  ? 250 LEU C N   1 
ATOM   9106  C CA  . LEU C 1 250 ? 45.462  60.908  50.458  1.00 25.46  ? 250 LEU C CA  1 
ATOM   9107  C C   . LEU C 1 250 ? 45.168  61.774  49.225  1.00 24.25  ? 250 LEU C C   1 
ATOM   9108  O O   . LEU C 1 250 ? 45.992  62.568  48.756  1.00 24.79  ? 250 LEU C O   1 
ATOM   9109  C CB  . LEU C 1 250 ? 45.560  59.412  50.137  1.00 24.24  ? 250 LEU C CB  1 
ATOM   9110  C CG  . LEU C 1 250 ? 46.561  59.026  49.040  1.00 24.04  ? 250 LEU C CG  1 
ATOM   9111  C CD1 . LEU C 1 250 ? 47.892  59.756  49.133  1.00 24.88  ? 250 LEU C CD1 1 
ATOM   9112  C CD2 . LEU C 1 250 ? 46.851  57.561  49.067  1.00 24.53  ? 250 LEU C CD2 1 
ATOM   9113  N N   . VAL C 1 251 ? 43.962  61.625  48.685  1.00 24.98  ? 251 VAL C N   1 
ATOM   9114  C CA  . VAL C 1 251 ? 43.616  62.306  47.459  1.00 24.92  ? 251 VAL C CA  1 
ATOM   9115  C C   . VAL C 1 251 ? 43.418  63.773  47.775  1.00 26.55  ? 251 VAL C C   1 
ATOM   9116  O O   . VAL C 1 251 ? 43.780  64.601  46.965  1.00 29.69  ? 251 VAL C O   1 
ATOM   9117  C CB  . VAL C 1 251 ? 42.382  61.681  46.802  1.00 25.95  ? 251 VAL C CB  1 
ATOM   9118  C CG1 . VAL C 1 251 ? 41.842  62.579  45.700  1.00 27.31  ? 251 VAL C CG1 1 
ATOM   9119  C CG2 . VAL C 1 251 ? 42.687  60.279  46.276  1.00 26.51  ? 251 VAL C CG2 1 
ATOM   9120  N N   . ASN C 1 252 ? 42.917  64.072  48.979  1.00 28.19  ? 252 ASN C N   1 
ATOM   9121  C CA  . ASN C 1 252 ? 42.762  65.440  49.453  1.00 30.93  ? 252 ASN C CA  1 
ATOM   9122  C C   . ASN C 1 252 ? 44.125  66.122  49.603  1.00 32.03  ? 252 ASN C C   1 
ATOM   9123  O O   . ASN C 1 252 ? 44.252  67.334  49.375  1.00 35.63  ? 252 ASN C O   1 
ATOM   9124  C CB  . ASN C 1 252 ? 41.967  65.493  50.761  1.00 32.00  ? 252 ASN C CB  1 
ATOM   9125  C CG  . ASN C 1 252 ? 42.066  66.850  51.426  1.00 33.52  ? 252 ASN C CG  1 
ATOM   9126  O OD1 . ASN C 1 252 ? 43.053  67.140  52.120  1.00 33.28  ? 252 ASN C OD1 1 
ATOM   9127  N ND2 . ASN C 1 252 ? 41.088  67.714  51.183  1.00 34.39  ? 252 ASN C ND2 1 
ATOM   9128  N N   . SER C 1 253 ? 45.153  65.344  49.978  1.00 32.07  ? 253 SER C N   1 
ATOM   9129  C CA  . SER C 1 253 ? 46.474  65.899  50.258  1.00 28.03  ? 253 SER C CA  1 
ATOM   9130  C C   . SER C 1 253 ? 47.095  66.559  49.030  1.00 29.53  ? 253 SER C C   1 
ATOM   9131  O O   . SER C 1 253 ? 47.968  67.402  49.220  1.00 27.28  ? 253 SER C O   1 
ATOM   9132  C CB  . SER C 1 253 ? 47.399  64.866  50.773  1.00 25.24  ? 253 SER C CB  1 
ATOM   9133  O OG  . SER C 1 253 ? 47.891  64.068  49.712  1.00 25.35  ? 253 SER C OG  1 
ATOM   9134  N N   . ALA C 1 254 ? 46.675  66.161  47.804  1.00 27.15  ? 254 ALA C N   1 
ATOM   9135  C CA  . ALA C 1 254 ? 47.179  66.768  46.573  1.00 26.27  ? 254 ALA C CA  1 
ATOM   9136  C C   . ALA C 1 254 ? 46.340  67.966  46.122  1.00 28.27  ? 254 ALA C C   1 
ATOM   9137  O O   . ALA C 1 254 ? 46.546  68.470  45.022  1.00 31.72  ? 254 ALA C O   1 
ATOM   9138  C CB  . ALA C 1 254 ? 47.276  65.744  45.452  1.00 24.18  ? 254 ALA C CB  1 
ATOM   9139  N N   . TYR C 1 255 ? 45.422  68.442  46.970  1.00 31.59  ? 255 TYR C N   1 
ATOM   9140  C CA  . TYR C 1 255 ? 44.564  69.593  46.682  1.00 30.68  ? 255 TYR C CA  1 
ATOM   9141  C C   . TYR C 1 255 ? 43.447  69.200  45.723  1.00 26.89  ? 255 TYR C C   1 
ATOM   9142  O O   . TYR C 1 255 ? 42.903  70.061  45.061  1.00 29.96  ? 255 TYR C O   1 
ATOM   9143  C CB  . TYR C 1 255 ? 45.243  70.867  46.151  1.00 31.61  ? 255 TYR C CB  1 
ATOM   9144  C CG  . TYR C 1 255 ? 46.183  71.571  47.132  1.00 35.10  ? 255 TYR C CG  1 
ATOM   9145  C CD1 . TYR C 1 255 ? 46.288  71.152  48.463  1.00 37.44  ? 255 TYR C CD1 1 
ATOM   9146  C CD2 . TYR C 1 255 ? 46.939  72.683  46.757  1.00 36.56  ? 255 TYR C CD2 1 
ATOM   9147  C CE1 . TYR C 1 255 ? 47.123  71.788  49.371  1.00 38.44  ? 255 TYR C CE1 1 
ATOM   9148  C CE2 . TYR C 1 255 ? 47.790  73.319  47.656  1.00 41.51  ? 255 TYR C CE2 1 
ATOM   9149  C CZ  . TYR C 1 255 ? 47.878  72.873  48.969  1.00 40.54  ? 255 TYR C CZ  1 
ATOM   9150  O OH  . TYR C 1 255 ? 48.693  73.433  49.905  1.00 40.47  ? 255 TYR C OH  1 
ATOM   9151  N N   . SER C 1 256 ? 43.117  67.908  45.661  1.00 26.14  ? 256 SER C N   1 
ATOM   9152  C CA  . SER C 1 256 ? 41.948  67.426  44.947  1.00 25.79  ? 256 SER C CA  1 
ATOM   9153  C C   . SER C 1 256 ? 40.711  67.669  45.807  1.00 26.68  ? 256 SER C C   1 
ATOM   9154  O O   . SER C 1 256 ? 40.718  67.285  46.970  1.00 30.23  ? 256 SER C O   1 
ATOM   9155  C CB  . SER C 1 256 ? 42.053  65.946  44.648  1.00 25.02  ? 256 SER C CB  1 
ATOM   9156  O OG  . SER C 1 256 ? 42.861  65.664  43.521  1.00 25.11  ? 256 SER C OG  1 
ATOM   9157  N N   . ASP C 1 257 ? 39.632  68.192  45.207  1.00 24.69  ? 257 ASP C N   1 
ATOM   9158  C CA  . ASP C 1 257 ? 38.446  68.574  45.950  1.00 26.74  ? 257 ASP C CA  1 
ATOM   9159  C C   . ASP C 1 257 ? 37.728  67.356  46.554  1.00 27.23  ? 257 ASP C C   1 
ATOM   9160  O O   . ASP C 1 257 ? 38.010  66.193  46.243  1.00 21.94  ? 257 ASP C O   1 
ATOM   9161  C CB  . ASP C 1 257 ? 37.528  69.451  45.105  1.00 25.83  ? 257 ASP C CB  1 
ATOM   9162  C CG  . ASP C 1 257 ? 36.998  68.795  43.844  1.00 28.10  ? 257 ASP C CG  1 
ATOM   9163  O OD1 . ASP C 1 257 ? 36.196  67.850  43.963  1.00 26.38  ? 257 ASP C OD1 1 
ATOM   9164  O OD2 . ASP C 1 257 ? 37.425  69.218  42.755  1.00 31.05  ? 257 ASP C OD2 1 
ATOM   9165  N N   . ILE C 1 258 ? 36.738  67.671  47.403  1.00 29.54  ? 258 ILE C N   1 
ATOM   9166  C CA  . ILE C 1 258 ? 35.969  66.681  48.151  1.00 31.32  ? 258 ILE C CA  1 
ATOM   9167  C C   . ILE C 1 258 ? 35.205  65.708  47.231  1.00 29.06  ? 258 ILE C C   1 
ATOM   9168  O O   . ILE C 1 258 ? 34.999  64.530  47.560  1.00 26.23  ? 258 ILE C O   1 
ATOM   9169  C CB  . ILE C 1 258 ? 35.038  67.413  49.134  1.00 31.74  ? 258 ILE C CB  1 
ATOM   9170  C CG1 . ILE C 1 258 ? 34.484  66.459  50.178  1.00 30.01  ? 258 ILE C CG1 1 
ATOM   9171  C CG2 . ILE C 1 258 ? 33.929  68.165  48.398  1.00 33.43  ? 258 ILE C CG2 1 
ATOM   9172  C CD1 . ILE C 1 258 ? 35.549  65.858  51.058  1.00 26.72  ? 258 ILE C CD1 1 
ATOM   9173  N N   . TYR C 1 259 ? 34.770  66.188  46.065  1.00 26.47  ? 259 TYR C N   1 
ATOM   9174  C CA  . TYR C 1 259 ? 34.085  65.311  45.136  1.00 24.28  ? 259 TYR C CA  1 
ATOM   9175  C C   . TYR C 1 259 ? 35.081  64.285  44.609  1.00 23.00  ? 259 TYR C C   1 
ATOM   9176  O O   . TYR C 1 259 ? 34.743  63.121  44.424  1.00 23.80  ? 259 TYR C O   1 
ATOM   9177  C CB  . TYR C 1 259 ? 33.415  66.114  44.027  1.00 24.18  ? 259 TYR C CB  1 
ATOM   9178  C CG  . TYR C 1 259 ? 32.377  67.131  44.466  1.00 23.40  ? 259 TYR C CG  1 
ATOM   9179  C CD1 . TYR C 1 259 ? 31.041  66.767  44.641  1.00 24.15  ? 259 TYR C CD1 1 
ATOM   9180  C CD2 . TYR C 1 259 ? 32.720  68.464  44.664  1.00 23.07  ? 259 TYR C CD2 1 
ATOM   9181  C CE1 . TYR C 1 259 ? 30.075  67.701  45.000  1.00 22.58  ? 259 TYR C CE1 1 
ATOM   9182  C CE2 . TYR C 1 259 ? 31.769  69.404  45.041  1.00 22.91  ? 259 TYR C CE2 1 
ATOM   9183  C CZ  . TYR C 1 259 ? 30.443  69.022  45.190  1.00 23.27  ? 259 TYR C CZ  1 
ATOM   9184  O OH  . TYR C 1 259 ? 29.506  69.947  45.542  1.00 28.09  ? 259 TYR C OH  1 
ATOM   9185  N N   . ARG C 1 260 ? 36.329  64.693  44.400  1.00 24.28  ? 260 ARG C N   1 
ATOM   9186  C CA  . ARG C 1 260 ? 37.332  63.738  43.937  1.00 23.13  ? 260 ARG C CA  1 
ATOM   9187  C C   . ARG C 1 260 ? 37.787  62.844  45.084  1.00 21.39  ? 260 ARG C C   1 
ATOM   9188  O O   . ARG C 1 260 ? 37.804  61.617  44.955  1.00 21.20  ? 260 ARG C O   1 
ATOM   9189  C CB  . ARG C 1 260 ? 38.475  64.505  43.281  1.00 25.77  ? 260 ARG C CB  1 
ATOM   9190  C CG  . ARG C 1 260 ? 38.170  64.885  41.831  1.00 28.09  ? 260 ARG C CG  1 
ATOM   9191  C CD  . ARG C 1 260 ? 39.090  65.970  41.299  1.00 26.58  ? 260 ARG C CD  1 
ATOM   9192  N NE  . ARG C 1 260 ? 38.999  66.125  39.850  1.00 25.54  ? 260 ARG C NE  1 
ATOM   9193  C CZ  . ARG C 1 260 ? 39.505  67.197  39.245  1.00 28.47  ? 260 ARG C CZ  1 
ATOM   9194  N NH1 . ARG C 1 260 ? 39.499  67.319  37.926  1.00 29.22  ? 260 ARG C NH1 1 
ATOM   9195  N NH2 . ARG C 1 260 ? 40.064  68.144  39.972  1.00 25.58  ? 260 ARG C NH2 1 
ATOM   9196  N N   . SER C 1 261 ? 38.098  63.460  46.234  1.00 20.85  ? 261 SER C N   1 
ATOM   9197  C CA  . SER C 1 261 ? 38.615  62.704  47.360  1.00 20.69  ? 261 SER C CA  1 
ATOM   9198  C C   . SER C 1 261 ? 37.554  61.732  47.882  1.00 22.62  ? 261 SER C C   1 
ATOM   9199  O O   . SER C 1 261 ? 37.839  60.541  48.092  1.00 23.23  ? 261 SER C O   1 
ATOM   9200  C CB  . SER C 1 261 ? 39.219  63.615  48.411  1.00 22.42  ? 261 SER C CB  1 
ATOM   9201  O OG  . SER C 1 261 ? 38.290  64.373  49.175  1.00 27.38  ? 261 SER C OG  1 
ATOM   9202  N N   . PHE C 1 262 ? 36.297  62.186  47.980  1.00 24.25  ? 262 PHE C N   1 
ATOM   9203  C CA  . PHE C 1 262 ? 35.266  61.370  48.598  1.00 25.52  ? 262 PHE C CA  1 
ATOM   9204  C C   . PHE C 1 262 ? 34.863  60.231  47.667  1.00 25.80  ? 262 PHE C C   1 
ATOM   9205  O O   . PHE C 1 262 ? 34.604  59.118  48.110  1.00 27.47  ? 262 PHE C O   1 
ATOM   9206  C CB  . PHE C 1 262 ? 34.032  62.171  49.028  1.00 28.24  ? 262 PHE C CB  1 
ATOM   9207  C CG  . PHE C 1 262 ? 33.125  61.322  49.901  1.00 26.47  ? 262 PHE C CG  1 
ATOM   9208  C CD1 . PHE C 1 262 ? 33.616  60.711  51.055  1.00 26.88  ? 262 PHE C CD1 1 
ATOM   9209  C CD2 . PHE C 1 262 ? 31.825  61.049  49.515  1.00 28.96  ? 262 PHE C CD2 1 
ATOM   9210  C CE1 . PHE C 1 262 ? 32.813  59.889  51.824  1.00 25.43  ? 262 PHE C CE1 1 
ATOM   9211  C CE2 . PHE C 1 262 ? 31.037  60.200  50.278  1.00 29.55  ? 262 PHE C CE2 1 
ATOM   9212  C CZ  . PHE C 1 262 ? 31.538  59.623  51.427  1.00 27.87  ? 262 PHE C CZ  1 
ATOM   9213  N N   . SER C 1 263 ? 34.782  60.505  46.368  1.00 25.89  ? 263 SER C N   1 
ATOM   9214  C CA  . SER C 1 263 ? 34.358  59.473  45.440  1.00 25.07  ? 263 SER C CA  1 
ATOM   9215  C C   . SER C 1 263 ? 35.424  58.391  45.363  1.00 23.30  ? 263 SER C C   1 
ATOM   9216  O O   . SER C 1 263 ? 35.089  57.218  45.281  1.00 21.09  ? 263 SER C O   1 
ATOM   9217  C CB  . SER C 1 263 ? 34.029  60.054  44.075  1.00 26.60  ? 263 SER C CB  1 
ATOM   9218  O OG  . SER C 1 263 ? 35.149  60.748  43.550  1.00 27.07  ? 263 SER C OG  1 
ATOM   9219  N N   . ALA C 1 264 ? 36.704  58.806  45.380  1.00 26.34  ? 264 ALA C N   1 
ATOM   9220  C CA  . ALA C 1 264 ? 37.830  57.882  45.547  1.00 27.59  ? 264 ALA C CA  1 
ATOM   9221  C C   . ALA C 1 264 ? 37.619  57.003  46.781  1.00 26.11  ? 264 ALA C C   1 
ATOM   9222  O O   . ALA C 1 264 ? 37.684  55.771  46.711  1.00 23.05  ? 264 ALA C O   1 
ATOM   9223  C CB  . ALA C 1 264 ? 39.132  58.652  45.658  1.00 27.67  ? 264 ALA C CB  1 
ATOM   9224  N N   . ALA C 1 265 ? 37.334  57.681  47.902  1.00 25.25  ? 265 ALA C N   1 
ATOM   9225  C CA  . ALA C 1 265 ? 37.100  57.029  49.175  1.00 25.21  ? 265 ALA C CA  1 
ATOM   9226  C C   . ALA C 1 265 ? 36.009  55.958  49.053  1.00 28.27  ? 265 ALA C C   1 
ATOM   9227  O O   . ALA C 1 265 ? 36.127  54.862  49.648  1.00 28.29  ? 265 ALA C O   1 
ATOM   9228  C CB  . ALA C 1 265 ? 36.748  58.086  50.180  1.00 24.56  ? 265 ALA C CB  1 
ATOM   9229  N N   . MET C 1 266 ? 34.951  56.269  48.274  1.00 26.17  ? 266 MET C N   1 
ATOM   9230  C CA  . MET C 1 266 ? 33.851  55.328  48.084  1.00 27.18  ? 266 MET C CA  1 
ATOM   9231  C C   . MET C 1 266 ? 34.316  54.114  47.273  1.00 27.56  ? 266 MET C C   1 
ATOM   9232  O O   . MET C 1 266 ? 33.864  52.995  47.538  1.00 28.16  ? 266 MET C O   1 
ATOM   9233  C CB  . MET C 1 266 ? 32.607  56.006  47.488  1.00 26.36  ? 266 MET C CB  1 
ATOM   9234  C CG  . MET C 1 266 ? 31.901  56.948  48.474  1.00 28.87  ? 266 MET C CG  1 
ATOM   9235  S SD  . MET C 1 266 ? 31.414  56.124  50.013  1.00 29.24  ? 266 MET C SD  1 
ATOM   9236  C CE  . MET C 1 266 ? 32.822  56.506  51.058  1.00 28.37  ? 266 MET C CE  1 
ATOM   9237  N N   . ASN C 1 267 ? 35.220  54.334  46.309  1.00 27.71  ? 267 ASN C N   1 
ATOM   9238  C CA  . ASN C 1 267 ? 35.812  53.252  45.535  1.00 28.92  ? 267 ASN C CA  1 
ATOM   9239  C C   . ASN C 1 267 ? 36.506  52.281  46.485  1.00 29.77  ? 267 ASN C C   1 
ATOM   9240  O O   . ASN C 1 267 ? 36.483  51.058  46.297  1.00 26.97  ? 267 ASN C O   1 
ATOM   9241  C CB  . ASN C 1 267 ? 36.750  53.792  44.461  1.00 27.54  ? 267 ASN C CB  1 
ATOM   9242  C CG  . ASN C 1 267 ? 35.995  54.336  43.270  1.00 27.34  ? 267 ASN C CG  1 
ATOM   9243  O OD1 . ASN C 1 267 ? 34.763  54.232  43.231  1.00 23.79  ? 267 ASN C OD1 1 
ATOM   9244  N ND2 . ASN C 1 267 ? 36.703  54.879  42.280  1.00 26.98  ? 267 ASN C ND2 1 
ATOM   9245  N N   . GLY C 1 268 ? 37.103  52.859  47.532  1.00 33.37  ? 268 GLY C N   1 
ATOM   9246  C CA  . GLY C 1 268 ? 37.735  52.085  48.592  1.00 34.03  ? 268 GLY C CA  1 
ATOM   9247  C C   . GLY C 1 268 ? 36.716  51.349  49.460  1.00 30.50  ? 268 GLY C C   1 
ATOM   9248  O O   . GLY C 1 268 ? 36.877  50.146  49.728  1.00 24.71  ? 268 GLY C O   1 
ATOM   9249  N N   . LEU C 1 269 ? 35.684  52.095  49.902  1.00 28.49  ? 269 LEU C N   1 
ATOM   9250  C CA  . LEU C 1 269 ? 34.639  51.520  50.736  1.00 28.01  ? 269 LEU C CA  1 
ATOM   9251  C C   . LEU C 1 269 ? 33.939  50.388  49.999  1.00 26.92  ? 269 LEU C C   1 
ATOM   9252  O O   . LEU C 1 269 ? 33.488  49.448  50.617  1.00 33.12  ? 269 LEU C O   1 
ATOM   9253  C CB  . LEU C 1 269 ? 33.659  52.597  51.184  1.00 30.86  ? 269 LEU C CB  1 
ATOM   9254  C CG  . LEU C 1 269 ? 32.558  52.153  52.146  1.00 31.79  ? 269 LEU C CG  1 
ATOM   9255  C CD1 . LEU C 1 269 ? 33.169  51.665  53.428  1.00 30.37  ? 269 LEU C CD1 1 
ATOM   9256  C CD2 . LEU C 1 269 ? 31.556  53.300  52.381  1.00 32.57  ? 269 LEU C CD2 1 
ATOM   9257  N N   . ALA C 1 270 ? 33.889  50.448  48.668  1.00 30.05  ? 270 ALA C N   1 
ATOM   9258  C CA  . ALA C 1 270 ? 33.267  49.401  47.869  1.00 26.35  ? 270 ALA C CA  1 
ATOM   9259  C C   . ALA C 1 270 ? 34.042  48.095  47.893  1.00 24.22  ? 270 ALA C C   1 
ATOM   9260  O O   . ALA C 1 270 ? 33.529  47.103  47.408  1.00 24.34  ? 270 ALA C O   1 
ATOM   9261  C CB  . ALA C 1 270 ? 33.165  49.862  46.456  1.00 29.58  ? 270 ALA C CB  1 
ATOM   9262  N N   . GLY C 1 271 ? 35.285  48.093  48.372  1.00 25.56  ? 271 GLY C N   1 
ATOM   9263  C CA  . GLY C 1 271 ? 36.075  46.875  48.398  1.00 26.68  ? 271 GLY C CA  1 
ATOM   9264  C C   . GLY C 1 271 ? 35.486  45.837  49.353  1.00 28.79  ? 271 GLY C C   1 
ATOM   9265  O O   . GLY C 1 271 ? 35.036  46.198  50.427  1.00 27.89  ? 271 GLY C O   1 
ATOM   9266  N N   . PRO C 1 272 ? 35.429  44.543  48.973  1.00 28.52  ? 272 PRO C N   1 
ATOM   9267  C CA  . PRO C 1 272 ? 34.956  43.477  49.855  1.00 34.06  ? 272 PRO C CA  1 
ATOM   9268  C C   . PRO C 1 272 ? 35.563  43.352  51.244  1.00 38.57  ? 272 PRO C C   1 
ATOM   9269  O O   . PRO C 1 272 ? 35.010  42.640  52.068  1.00 42.11  ? 272 PRO C O   1 
ATOM   9270  C CB  . PRO C 1 272 ? 35.304  42.209  49.072  1.00 36.38  ? 272 PRO C CB  1 
ATOM   9271  C CG  . PRO C 1 272 ? 35.219  42.635  47.623  1.00 33.91  ? 272 PRO C CG  1 
ATOM   9272  C CD  . PRO C 1 272 ? 35.757  44.053  47.632  1.00 31.07  ? 272 PRO C CD  1 
ATOM   9273  N N   . LEU C 1 273 ? 36.733  43.957  51.482  1.00 40.51  ? 273 LEU C N   1 
ATOM   9274  C CA  . LEU C 1 273 ? 37.382  43.829  52.780  1.00 39.79  ? 273 LEU C CA  1 
ATOM   9275  C C   . LEU C 1 273 ? 37.029  45.013  53.686  1.00 42.52  ? 273 LEU C C   1 
ATOM   9276  O O   . LEU C 1 273 ? 37.183  44.926  54.914  1.00 41.78  ? 273 LEU C O   1 
ATOM   9277  C CB  . LEU C 1 273 ? 38.899  43.678  52.627  1.00 38.81  ? 273 LEU C CB  1 
ATOM   9278  C CG  . LEU C 1 273 ? 39.444  42.405  51.958  1.00 35.21  ? 273 LEU C CG  1 
ATOM   9279  C CD1 . LEU C 1 273 ? 40.957  42.365  52.214  1.00 36.27  ? 273 LEU C CD1 1 
ATOM   9280  C CD2 . LEU C 1 273 ? 38.818  41.096  52.400  1.00 31.37  ? 273 LEU C CD2 1 
ATOM   9281  N N   . HIS C 1 274 ? 36.532  46.105  53.078  1.00 42.90  ? 274 HIS C N   1 
ATOM   9282  C CA  . HIS C 1 274 ? 36.165  47.313  53.814  1.00 39.99  ? 274 HIS C CA  1 
ATOM   9283  C C   . HIS C 1 274 ? 34.653  47.462  54.066  1.00 40.44  ? 274 HIS C C   1 
ATOM   9284  O O   . HIS C 1 274 ? 34.284  48.048  55.086  1.00 38.67  ? 274 HIS C O   1 
ATOM   9285  C CB  . HIS C 1 274 ? 36.705  48.543  53.077  1.00 39.96  ? 274 HIS C CB  1 
ATOM   9286  C CG  . HIS C 1 274 ? 36.653  49.800  53.877  1.00 38.58  ? 274 HIS C CG  1 
ATOM   9287  N ND1 . HIS C 1 274 ? 36.272  49.839  55.207  1.00 38.21  ? 274 HIS C ND1 1 
ATOM   9288  C CD2 . HIS C 1 274 ? 36.896  51.069  53.515  1.00 35.75  ? 274 HIS C CD2 1 
ATOM   9289  C CE1 . HIS C 1 274 ? 36.302  51.092  55.634  1.00 35.31  ? 274 HIS C CE1 1 
ATOM   9290  N NE2 . HIS C 1 274 ? 36.681  51.855  54.620  1.00 36.47  ? 274 HIS C NE2 1 
ATOM   9291  N N   . GLY C 1 275 ? 33.771  46.956  53.176  1.00 33.00  ? 275 GLY C N   1 
ATOM   9292  C CA  . GLY C 1 275 ? 32.421  47.500  53.074  1.00 33.27  ? 275 GLY C CA  1 
ATOM   9293  C C   . GLY C 1 275 ? 31.263  46.497  53.214  1.00 35.53  ? 275 GLY C C   1 
ATOM   9294  O O   . GLY C 1 275 ? 30.108  46.913  53.041  1.00 35.28  ? 275 GLY C O   1 
ATOM   9295  N N   . LEU C 1 276 ? 31.536  45.227  53.578  1.00 33.29  ? 276 LEU C N   1 
ATOM   9296  C CA  . LEU C 1 276 ? 30.547  44.166  53.442  1.00 35.34  ? 276 LEU C CA  1 
ATOM   9297  C C   . LEU C 1 276 ? 30.113  43.510  54.767  1.00 39.82  ? 276 LEU C C   1 
ATOM   9298  O O   . LEU C 1 276 ? 29.188  42.671  54.786  1.00 34.99  ? 276 LEU C O   1 
ATOM   9299  C CB  . LEU C 1 276 ? 31.135  43.110  52.509  1.00 33.72  ? 276 LEU C CB  1 
ATOM   9300  C CG  . LEU C 1 276 ? 31.185  43.432  51.016  1.00 35.72  ? 276 LEU C CG  1 
ATOM   9301  C CD1 . LEU C 1 276 ? 31.303  42.063  50.334  1.00 34.93  ? 276 LEU C CD1 1 
ATOM   9302  C CD2 . LEU C 1 276 ? 30.046  44.286  50.416  1.00 33.81  ? 276 LEU C CD2 1 
ATOM   9303  N N   . ALA C 1 277 ? 30.788  43.836  55.875  1.00 40.86  ? 277 ALA C N   1 
ATOM   9304  C CA  . ALA C 1 277 ? 30.627  43.047  57.091  1.00 42.77  ? 277 ALA C CA  1 
ATOM   9305  C C   . ALA C 1 277 ? 29.146  42.985  57.516  1.00 47.48  ? 277 ALA C C   1 
ATOM   9306  O O   . ALA C 1 277 ? 28.570  41.897  57.676  1.00 48.50  ? 277 ALA C O   1 
ATOM   9307  C CB  . ALA C 1 277 ? 31.543  43.614  58.166  1.00 40.94  ? 277 ALA C CB  1 
ATOM   9308  N N   . ASN C 1 278 ? 28.532  44.175  57.658  1.00 49.41  ? 278 ASN C N   1 
ATOM   9309  C CA  . ASN C 1 278 ? 27.106  44.369  57.920  1.00 44.86  ? 278 ASN C CA  1 
ATOM   9310  C C   . ASN C 1 278 ? 26.281  43.275  57.250  1.00 41.42  ? 278 ASN C C   1 
ATOM   9311  O O   . ASN C 1 278 ? 25.481  42.631  57.919  1.00 47.44  ? 278 ASN C O   1 
ATOM   9312  C CB  . ASN C 1 278 ? 26.725  45.783  57.491  1.00 47.12  ? 278 ASN C CB  1 
ATOM   9313  C CG  . ASN C 1 278 ? 25.251  46.091  57.532  1.00 53.19  ? 278 ASN C CG  1 
ATOM   9314  O OD1 . ASN C 1 278 ? 24.431  45.203  57.770  1.00 69.50  ? 278 ASN C OD1 1 
ATOM   9315  N ND2 . ASN C 1 278 ? 24.897  47.350  57.316  1.00 53.25  ? 278 ASN C ND2 1 
ATOM   9316  N N   . GLN C 1 279 ? 26.527  43.064  55.946  1.00 44.02  ? 279 GLN C N   1 
ATOM   9317  C CA  . GLN C 1 279 ? 25.724  42.214  55.073  1.00 43.36  ? 279 GLN C CA  1 
ATOM   9318  C C   . GLN C 1 279 ? 25.989  40.736  55.360  1.00 39.80  ? 279 GLN C C   1 
ATOM   9319  O O   . GLN C 1 279 ? 25.061  39.932  55.356  1.00 36.78  ? 279 GLN C O   1 
ATOM   9320  C CB  . GLN C 1 279 ? 26.004  42.483  53.585  1.00 45.96  ? 279 GLN C CB  1 
ATOM   9321  C CG  . GLN C 1 279 ? 26.171  43.966  53.244  1.00 49.33  ? 279 GLN C CG  1 
ATOM   9322  C CD  . GLN C 1 279 ? 26.529  44.261  51.800  1.00 49.79  ? 279 GLN C CD  1 
ATOM   9323  O OE1 . GLN C 1 279 ? 26.378  43.440  50.880  1.00 50.00  ? 279 GLN C OE1 1 
ATOM   9324  N NE2 . GLN C 1 279 ? 27.010  45.480  51.596  1.00 52.68  ? 279 GLN C NE2 1 
ATOM   9325  N N   . GLU C 1 280 ? 27.268  40.384  55.543  1.00 42.32  ? 280 GLU C N   1 
ATOM   9326  C CA  . GLU C 1 280 ? 27.665  39.012  55.804  1.00 45.40  ? 280 GLU C CA  1 
ATOM   9327  C C   . GLU C 1 280 ? 27.027  38.562  57.122  1.00 45.89  ? 280 GLU C C   1 
ATOM   9328  O O   . GLU C 1 280 ? 26.479  37.461  57.191  1.00 40.68  ? 280 GLU C O   1 
ATOM   9329  C CB  . GLU C 1 280 ? 29.193  38.898  55.856  1.00 50.52  ? 280 GLU C CB  1 
ATOM   9330  C CG  . GLU C 1 280 ? 29.885  38.954  54.496  1.00 56.19  ? 280 GLU C CG  1 
ATOM   9331  C CD  . GLU C 1 280 ? 31.341  39.430  54.477  1.00 55.18  ? 280 GLU C CD  1 
ATOM   9332  O OE1 . GLU C 1 280 ? 31.907  39.435  53.366  1.00 55.33  ? 280 GLU C OE1 1 
ATOM   9333  O OE2 . GLU C 1 280 ? 31.921  39.806  55.519  1.00 51.94  ? 280 GLU C OE2 1 
ATOM   9334  N N   . VAL C 1 281 ? 27.114  39.418  58.155  1.00 41.30  ? 281 VAL C N   1 
ATOM   9335  C CA  . VAL C 1 281 ? 26.476  39.143  59.434  1.00 48.02  ? 281 VAL C CA  1 
ATOM   9336  C C   . VAL C 1 281 ? 25.003  38.824  59.218  1.00 46.97  ? 281 VAL C C   1 
ATOM   9337  O O   . VAL C 1 281 ? 24.506  37.804  59.688  1.00 49.43  ? 281 VAL C O   1 
ATOM   9338  C CB  . VAL C 1 281 ? 26.563  40.278  60.466  1.00 54.47  ? 281 VAL C CB  1 
ATOM   9339  C CG1 . VAL C 1 281 ? 25.605  40.032  61.632  1.00 56.67  ? 281 VAL C CG1 1 
ATOM   9340  C CG2 . VAL C 1 281 ? 27.987  40.497  60.967  1.00 53.09  ? 281 VAL C CG2 1 
ATOM   9341  N N   . LEU C 1 282 ? 24.304  39.733  58.544  1.00 45.62  ? 282 LEU C N   1 
ATOM   9342  C CA  . LEU C 1 282 ? 22.877  39.568  58.335  1.00 45.34  ? 282 LEU C CA  1 
ATOM   9343  C C   . LEU C 1 282 ? 22.602  38.246  57.631  1.00 44.84  ? 282 LEU C C   1 
ATOM   9344  O O   . LEU C 1 282 ? 21.609  37.591  57.941  1.00 49.60  ? 282 LEU C O   1 
ATOM   9345  C CB  . LEU C 1 282 ? 22.282  40.742  57.554  1.00 45.30  ? 282 LEU C CB  1 
ATOM   9346  C CG  . LEU C 1 282 ? 20.801  40.604  57.182  1.00 45.64  ? 282 LEU C CG  1 
ATOM   9347  C CD1 . LEU C 1 282 ? 19.950  40.446  58.438  1.00 45.81  ? 282 LEU C CD1 1 
ATOM   9348  C CD2 . LEU C 1 282 ? 20.308  41.774  56.333  1.00 48.21  ? 282 LEU C CD2 1 
ATOM   9349  N N   . ARG C 1 283 ? 23.436  37.895  56.639  1.00 49.36  ? 283 ARG C N   1 
ATOM   9350  C CA  . ARG C 1 283 ? 23.150  36.754  55.777  1.00 51.73  ? 283 ARG C CA  1 
ATOM   9351  C C   . ARG C 1 283 ? 23.250  35.481  56.607  1.00 50.78  ? 283 ARG C C   1 
ATOM   9352  O O   . ARG C 1 283 ? 22.496  34.529  56.392  1.00 47.90  ? 283 ARG C O   1 
ATOM   9353  C CB  . ARG C 1 283 ? 24.079  36.673  54.559  1.00 53.81  ? 283 ARG C CB  1 
ATOM   9354  C CG  . ARG C 1 283 ? 23.657  37.539  53.381  1.00 51.59  ? 283 ARG C CG  1 
ATOM   9355  C CD  . ARG C 1 283 ? 24.630  37.416  52.222  1.00 51.97  ? 283 ARG C CD  1 
ATOM   9356  N NE  . ARG C 1 283 ? 24.384  38.394  51.150  1.00 53.83  ? 283 ARG C NE  1 
ATOM   9357  C CZ  . ARG C 1 283 ? 23.422  38.354  50.221  1.00 49.94  ? 283 ARG C CZ  1 
ATOM   9358  N NH1 . ARG C 1 283 ? 22.530  37.368  50.186  1.00 50.19  ? 283 ARG C NH1 1 
ATOM   9359  N NH2 . ARG C 1 283 ? 23.355  39.328  49.328  1.00 46.35  ? 283 ARG C NH2 1 
ATOM   9360  N N   . TRP C 1 284 ? 24.207  35.523  57.542  1.00 50.48  ? 284 TRP C N   1 
ATOM   9361  C CA  . TRP C 1 284 ? 24.493  34.466  58.496  1.00 52.86  ? 284 TRP C CA  1 
ATOM   9362  C C   . TRP C 1 284 ? 23.291  34.257  59.413  1.00 53.28  ? 284 TRP C C   1 
ATOM   9363  O O   . TRP C 1 284 ? 22.654  33.208  59.355  1.00 45.81  ? 284 TRP C O   1 
ATOM   9364  C CB  . TRP C 1 284 ? 25.745  34.878  59.271  1.00 52.70  ? 284 TRP C CB  1 
ATOM   9365  C CG  . TRP C 1 284 ? 26.343  33.835  60.165  1.00 64.49  ? 284 TRP C CG  1 
ATOM   9366  C CD1 . TRP C 1 284 ? 27.074  32.747  59.790  1.00 67.49  ? 284 TRP C CD1 1 
ATOM   9367  C CD2 . TRP C 1 284 ? 26.356  33.862  61.607  1.00 68.78  ? 284 TRP C CD2 1 
ATOM   9368  N NE1 . TRP C 1 284 ? 27.506  32.073  60.899  1.00 75.79  ? 284 TRP C NE1 1 
ATOM   9369  C CE2 . TRP C 1 284 ? 27.092  32.736  62.026  1.00 71.00  ? 284 TRP C CE2 1 
ATOM   9370  C CE3 . TRP C 1 284 ? 25.809  34.712  62.573  1.00 69.23  ? 284 TRP C CE3 1 
ATOM   9371  C CZ2 . TRP C 1 284 ? 27.290  32.442  63.372  1.00 66.43  ? 284 TRP C CZ2 1 
ATOM   9372  C CZ3 . TRP C 1 284 ? 26.010  34.425  63.902  1.00 65.67  ? 284 TRP C CZ3 1 
ATOM   9373  C CH2 . TRP C 1 284 ? 26.750  33.309  64.290  1.00 66.89  ? 284 TRP C CH2 1 
ATOM   9374  N N   . ILE C 1 285 ? 22.952  35.306  60.178  1.00 50.27  ? 285 ILE C N   1 
ATOM   9375  C CA  . ILE C 1 285 ? 21.747  35.343  60.988  1.00 49.10  ? 285 ILE C CA  1 
ATOM   9376  C C   . ILE C 1 285 ? 20.581  34.693  60.243  1.00 47.86  ? 285 ILE C C   1 
ATOM   9377  O O   . ILE C 1 285 ? 19.880  33.853  60.803  1.00 52.27  ? 285 ILE C O   1 
ATOM   9378  C CB  . ILE C 1 285 ? 21.391  36.781  61.403  1.00 47.28  ? 285 ILE C CB  1 
ATOM   9379  C CG1 . ILE C 1 285 ? 22.456  37.420  62.273  1.00 46.64  ? 285 ILE C CG1 1 
ATOM   9380  C CG2 . ILE C 1 285 ? 20.037  36.803  62.102  1.00 51.10  ? 285 ILE C CG2 1 
ATOM   9381  C CD1 . ILE C 1 285 ? 22.584  36.839  63.669  1.00 46.91  ? 285 ILE C CD1 1 
ATOM   9382  N N   . GLN C 1 286 ? 20.353  35.076  58.988  1.00 43.67  ? 286 GLN C N   1 
ATOM   9383  C CA  . GLN C 1 286 ? 19.193  34.551  58.286  1.00 44.94  ? 286 GLN C CA  1 
ATOM   9384  C C   . GLN C 1 286 ? 19.389  33.073  57.974  1.00 47.28  ? 286 GLN C C   1 
ATOM   9385  O O   . GLN C 1 286 ? 18.407  32.355  57.876  1.00 52.25  ? 286 GLN C O   1 
ATOM   9386  C CB  . GLN C 1 286 ? 18.851  35.341  57.022  1.00 48.10  ? 286 GLN C CB  1 
ATOM   9387  C CG  . GLN C 1 286 ? 18.268  36.726  57.296  1.00 47.56  ? 286 GLN C CG  1 
ATOM   9388  C CD  . GLN C 1 286 ? 18.286  37.606  56.074  1.00 43.54  ? 286 GLN C CD  1 
ATOM   9389  O OE1 . GLN C 1 286 ? 17.247  38.004  55.550  1.00 39.22  ? 286 GLN C OE1 1 
ATOM   9390  N NE2 . GLN C 1 286 ? 19.485  37.895  55.598  1.00 44.34  ? 286 GLN C NE2 1 
ATOM   9391  N N   . MET C 1 287 ? 20.642  32.629  57.780  1.00 55.54  ? 287 MET C N   1 
ATOM   9392  C CA  . MET C 1 287 ? 20.952  31.225  57.525  1.00 55.15  ? 287 MET C CA  1 
ATOM   9393  C C   . MET C 1 287 ? 20.609  30.384  58.761  1.00 52.68  ? 287 MET C C   1 
ATOM   9394  O O   . MET C 1 287 ? 20.039  29.300  58.616  1.00 41.87  ? 287 MET C O   1 
ATOM   9395  C CB  . MET C 1 287 ? 22.430  31.064  57.129  1.00 59.77  ? 287 MET C CB  1 
ATOM   9396  C CG  . MET C 1 287 ? 22.982  29.633  57.141  1.00 57.71  ? 287 MET C CG  1 
ATOM   9397  S SD  . MET C 1 287 ? 23.713  29.095  58.706  1.00 55.09  ? 287 MET C SD  1 
ATOM   9398  C CE  . MET C 1 287 ? 25.000  30.240  59.224  1.00 49.95  ? 287 MET C CE  1 
ATOM   9399  N N   . LEU C 1 288 ? 20.992  30.889  59.955  1.00 53.44  ? 288 LEU C N   1 
ATOM   9400  C CA  . LEU C 1 288 ? 20.627  30.318  61.250  1.00 56.96  ? 288 LEU C CA  1 
ATOM   9401  C C   . LEU C 1 288 ? 19.110  30.113  61.290  1.00 64.88  ? 288 LEU C C   1 
ATOM   9402  O O   . LEU C 1 288 ? 18.620  28.996  61.478  1.00 66.97  ? 288 LEU C O   1 
ATOM   9403  C CB  . LEU C 1 288 ? 21.086  31.211  62.408  1.00 56.11  ? 288 LEU C CB  1 
ATOM   9404  C CG  . LEU C 1 288 ? 22.575  31.172  62.792  1.00 54.76  ? 288 LEU C CG  1 
ATOM   9405  C CD1 . LEU C 1 288 ? 23.014  32.254  63.778  1.00 46.11  ? 288 LEU C CD1 1 
ATOM   9406  C CD2 . LEU C 1 288 ? 22.903  29.814  63.374  1.00 57.61  ? 288 LEU C CD2 1 
ATOM   9407  N N   . TYR C 1 289 ? 18.367  31.198  61.051  1.00 60.45  ? 289 TYR C N   1 
ATOM   9408  C CA  . TYR C 1 289 ? 16.919  31.136  61.047  1.00 60.23  ? 289 TYR C CA  1 
ATOM   9409  C C   . TYR C 1 289 ? 16.408  30.033  60.115  1.00 63.75  ? 289 TYR C C   1 
ATOM   9410  O O   . TYR C 1 289 ? 15.467  29.325  60.467  1.00 66.70  ? 289 TYR C O   1 
ATOM   9411  C CB  . TYR C 1 289 ? 16.335  32.501  60.688  1.00 61.63  ? 289 TYR C CB  1 
ATOM   9412  C CG  . TYR C 1 289 ? 14.822  32.496  60.809  1.00 67.87  ? 289 TYR C CG  1 
ATOM   9413  C CD1 . TYR C 1 289 ? 14.023  32.085  59.743  1.00 72.54  ? 289 TYR C CD1 1 
ATOM   9414  C CD2 . TYR C 1 289 ? 14.204  32.839  62.008  1.00 63.79  ? 289 TYR C CD2 1 
ATOM   9415  C CE1 . TYR C 1 289 ? 12.644  32.037  59.858  1.00 74.64  ? 289 TYR C CE1 1 
ATOM   9416  C CE2 . TYR C 1 289 ? 12.827  32.809  62.131  1.00 63.64  ? 289 TYR C CE2 1 
ATOM   9417  C CZ  . TYR C 1 289 ? 12.051  32.407  61.056  1.00 73.38  ? 289 TYR C CZ  1 
ATOM   9418  O OH  . TYR C 1 289 ? 10.696  32.361  61.173  1.00 79.76  ? 289 TYR C OH  1 
ATOM   9419  N N   . LYS C 1 290 ? 16.995  29.882  58.921  1.00 73.83  ? 290 LYS C N   1 
ATOM   9420  C CA  . LYS C 1 290 ? 16.508  28.891  57.963  1.00 72.53  ? 290 LYS C CA  1 
ATOM   9421  C C   . LYS C 1 290 ? 16.879  27.486  58.430  1.00 70.48  ? 290 LYS C C   1 
ATOM   9422  O O   . LYS C 1 290 ? 16.066  26.571  58.317  1.00 70.28  ? 290 LYS C O   1 
ATOM   9423  C CB  . LYS C 1 290 ? 17.037  29.038  56.531  1.00 73.03  ? 290 LYS C CB  1 
ATOM   9424  C CG  . LYS C 1 290 ? 16.448  28.021  55.548  1.00 76.83  ? 290 LYS C CG  1 
ATOM   9425  C CD  . LYS C 1 290 ? 16.767  28.210  54.065  1.00 76.17  ? 290 LYS C CD  1 
ATOM   9426  C CE  . LYS C 1 290 ? 15.868  27.344  53.218  1.00 78.89  ? 290 LYS C CE  1 
ATOM   9427  N NZ  . LYS C 1 290 ? 16.146  27.390  51.779  1.00 75.47  ? 290 LYS C NZ  1 
ATOM   9428  N N   . LYS C 1 291 ? 18.108  27.340  58.942  1.00 71.48  ? 291 LYS C N   1 
ATOM   9429  C CA  . LYS C 1 291 ? 18.628  26.065  59.413  1.00 72.40  ? 291 LYS C CA  1 
ATOM   9430  C C   . LYS C 1 291 ? 17.697  25.471  60.472  1.00 75.93  ? 291 LYS C C   1 
ATOM   9431  O O   . LYS C 1 291 ? 17.181  24.367  60.287  1.00 72.53  ? 291 LYS C O   1 
ATOM   9432  C CB  . LYS C 1 291 ? 20.054  26.234  59.956  1.00 65.49  ? 291 LYS C CB  1 
ATOM   9433  C CG  . LYS C 1 291 ? 20.787  24.933  60.213  1.00 66.58  ? 291 LYS C CG  1 
ATOM   9434  C CD  . LYS C 1 291 ? 22.263  25.101  60.553  1.00 72.19  ? 291 LYS C CD  1 
ATOM   9435  C CE  . LYS C 1 291 ? 22.874  23.869  61.165  1.00 72.98  ? 291 LYS C CE  1 
ATOM   9436  N NZ  . LYS C 1 291 ? 22.789  22.712  60.272  1.00 71.00  ? 291 LYS C NZ  1 
ATOM   9437  N N   . PHE C 1 292 ? 17.453  26.232  61.550  1.00 68.34  ? 292 PHE C N   1 
ATOM   9438  C CA  . PHE C 1 292 ? 16.701  25.743  62.694  1.00 70.01  ? 292 PHE C CA  1 
ATOM   9439  C C   . PHE C 1 292 ? 15.191  25.981  62.592  1.00 72.12  ? 292 PHE C C   1 
ATOM   9440  O O   . PHE C 1 292 ? 14.513  25.913  63.614  1.00 73.71  ? 292 PHE C O   1 
ATOM   9441  C CB  . PHE C 1 292 ? 17.248  26.455  63.929  1.00 68.59  ? 292 PHE C CB  1 
ATOM   9442  C CG  . PHE C 1 292 ? 18.678  26.042  64.213  1.00 74.89  ? 292 PHE C CG  1 
ATOM   9443  C CD1 . PHE C 1 292 ? 18.949  24.831  64.843  1.00 75.45  ? 292 PHE C CD1 1 
ATOM   9444  C CD2 . PHE C 1 292 ? 19.741  26.852  63.841  1.00 73.66  ? 292 PHE C CD2 1 
ATOM   9445  C CE1 . PHE C 1 292 ? 20.256  24.452  65.110  1.00 76.83  ? 292 PHE C CE1 1 
ATOM   9446  C CE2 . PHE C 1 292 ? 21.045  26.466  64.110  1.00 74.20  ? 292 PHE C CE2 1 
ATOM   9447  C CZ  . PHE C 1 292 ? 21.300  25.268  64.739  1.00 76.82  ? 292 PHE C CZ  1 
ATOM   9448  N N   . GLY C 1 293 ? 14.657  26.265  61.394  1.00 65.75  ? 293 GLY C N   1 
ATOM   9449  C CA  . GLY C 1 293 ? 13.242  26.590  61.215  1.00 67.03  ? 293 GLY C CA  1 
ATOM   9450  C C   . GLY C 1 293 ? 12.686  27.578  62.253  1.00 66.03  ? 293 GLY C C   1 
ATOM   9451  O O   . GLY C 1 293 ? 11.480  27.583  62.520  1.00 71.09  ? 293 GLY C O   1 
ATOM   9452  N N   . GLY C 1 294 ? 13.559  28.423  62.824  1.00 56.63  ? 294 GLY C N   1 
ATOM   9453  C CA  . GLY C 1 294 ? 13.165  29.435  63.790  1.00 50.77  ? 294 GLY C CA  1 
ATOM   9454  C C   . GLY C 1 294 ? 14.362  29.873  64.627  1.00 51.47  ? 294 GLY C C   1 
ATOM   9455  O O   . GLY C 1 294 ? 15.511  29.635  64.262  1.00 52.35  ? 294 GLY C O   1 
ATOM   9456  N N   . VAL C 1 295 ? 14.086  30.500  65.766  1.00 48.13  ? 295 VAL C N   1 
ATOM   9457  C CA  . VAL C 1 295 ? 15.152  30.877  66.667  1.00 56.12  ? 295 VAL C CA  1 
ATOM   9458  C C   . VAL C 1 295 ? 15.683  29.582  67.274  1.00 71.67  ? 295 VAL C C   1 
ATOM   9459  O O   . VAL C 1 295 ? 14.901  28.687  67.589  1.00 75.81  ? 295 VAL C O   1 
ATOM   9460  C CB  . VAL C 1 295 ? 14.645  31.887  67.714  1.00 55.04  ? 295 VAL C CB  1 
ATOM   9461  C CG1 . VAL C 1 295 ? 15.677  32.226  68.789  1.00 44.65  ? 295 VAL C CG1 1 
ATOM   9462  C CG2 . VAL C 1 295 ? 14.151  33.160  67.026  1.00 58.82  ? 295 VAL C CG2 1 
ATOM   9463  N N   . PRO C 1 296 ? 17.021  29.394  67.334  1.00 77.34  ? 296 PRO C N   1 
ATOM   9464  C CA  . PRO C 1 296 ? 17.603  28.237  68.015  1.00 76.72  ? 296 PRO C CA  1 
ATOM   9465  C C   . PRO C 1 296 ? 17.603  28.404  69.528  1.00 75.47  ? 296 PRO C C   1 
ATOM   9466  O O   . PRO C 1 296 ? 17.543  29.533  70.009  1.00 72.06  ? 296 PRO C O   1 
ATOM   9467  C CB  . PRO C 1 296 ? 19.035  28.246  67.436  1.00 76.83  ? 296 PRO C CB  1 
ATOM   9468  C CG  . PRO C 1 296 ? 19.339  29.712  67.242  1.00 71.60  ? 296 PRO C CG  1 
ATOM   9469  C CD  . PRO C 1 296 ? 18.035  30.247  66.689  1.00 73.58  ? 296 PRO C CD  1 
ATOM   9470  N N   . THR C 1 297 ? 17.736  27.290  70.264  1.00 78.17  ? 297 THR C N   1 
ATOM   9471  C CA  . THR C 1 297 ? 17.950  27.358  71.707  1.00 76.67  ? 297 THR C CA  1 
ATOM   9472  C C   . THR C 1 297 ? 19.419  27.667  71.986  1.00 73.07  ? 297 THR C C   1 
ATOM   9473  O O   . THR C 1 297 ? 20.295  27.421  71.154  1.00 68.57  ? 297 THR C O   1 
ATOM   9474  C CB  . THR C 1 297 ? 17.542  26.078  72.443  1.00 81.04  ? 297 THR C CB  1 
ATOM   9475  O OG1 . THR C 1 297 ? 18.569  25.107  72.262  1.00 82.96  ? 297 THR C OG1 1 
ATOM   9476  C CG2 . THR C 1 297 ? 16.204  25.524  71.991  1.00 83.42  ? 297 THR C CG2 1 
ATOM   9477  N N   . LYS C 1 298 ? 19.656  28.178  73.198  1.00 72.32  ? 298 LYS C N   1 
ATOM   9478  C CA  . LYS C 1 298 ? 20.985  28.402  73.747  1.00 76.42  ? 298 LYS C CA  1 
ATOM   9479  C C   . LYS C 1 298 ? 21.911  27.222  73.464  1.00 85.93  ? 298 LYS C C   1 
ATOM   9480  O O   . LYS C 1 298 ? 23.107  27.415  73.252  1.00 92.73  ? 298 LYS C O   1 
ATOM   9481  C CB  . LYS C 1 298 ? 20.850  28.580  75.263  1.00 74.88  ? 298 LYS C CB  1 
ATOM   9482  C CG  . LYS C 1 298 ? 21.964  29.323  75.990  1.00 75.01  ? 298 LYS C CG  1 
ATOM   9483  C CD  . LYS C 1 298 ? 21.457  29.907  77.306  1.00 76.90  ? 298 LYS C CD  1 
ATOM   9484  C CE  . LYS C 1 298 ? 22.365  30.929  77.903  1.00 85.24  ? 298 LYS C CE  1 
ATOM   9485  N NZ  . LYS C 1 298 ? 23.553  30.355  78.538  1.00 85.95  ? 298 LYS C NZ  1 
ATOM   9486  N N   . GLU C 1 299 ? 21.366  26.000  73.508  1.00 92.66  ? 299 GLU C N   1 
ATOM   9487  C CA  . GLU C 1 299 ? 22.187  24.818  73.322  1.00 97.35  ? 299 GLU C CA  1 
ATOM   9488  C C   . GLU C 1 299 ? 22.529  24.683  71.840  1.00 86.61  ? 299 GLU C C   1 
ATOM   9489  O O   . GLU C 1 299 ? 23.701  24.567  71.501  1.00 100.10 ? 299 GLU C O   1 
ATOM   9490  C CB  . GLU C 1 299 ? 21.566  23.553  73.919  1.00 107.67 ? 299 GLU C CB  1 
ATOM   9491  C CG  . GLU C 1 299 ? 22.587  22.422  74.060  1.00 113.12 ? 299 GLU C CG  1 
ATOM   9492  C CD  . GLU C 1 299 ? 22.229  21.271  74.986  1.00 105.67 ? 299 GLU C CD  1 
ATOM   9493  O OE1 . GLU C 1 299 ? 21.836  21.547  76.140  1.00 97.67  ? 299 GLU C OE1 1 
ATOM   9494  O OE2 . GLU C 1 299 ? 22.376  20.102  74.562  1.00 95.61  ? 299 GLU C OE2 1 
ATOM   9495  N N   . GLN C 1 300 ? 21.514  24.728  70.967  1.00 72.55  ? 300 GLN C N   1 
ATOM   9496  C CA  . GLN C 1 300 ? 21.720  24.562  69.535  1.00 66.13  ? 300 GLN C CA  1 
ATOM   9497  C C   . GLN C 1 300 ? 22.719  25.598  69.010  1.00 66.62  ? 300 GLN C C   1 
ATOM   9498  O O   . GLN C 1 300 ? 23.505  25.296  68.116  1.00 58.19  ? 300 GLN C O   1 
ATOM   9499  C CB  . GLN C 1 300 ? 20.421  24.693  68.739  1.00 62.77  ? 300 GLN C CB  1 
ATOM   9500  C CG  . GLN C 1 300 ? 19.349  23.655  69.068  1.00 60.34  ? 300 GLN C CG  1 
ATOM   9501  C CD  . GLN C 1 300 ? 17.993  23.999  68.483  1.00 53.56  ? 300 GLN C CD  1 
ATOM   9502  O OE1 . GLN C 1 300 ? 17.368  25.016  68.822  1.00 50.95  ? 300 GLN C OE1 1 
ATOM   9503  N NE2 . GLN C 1 300 ? 17.529  23.163  67.570  1.00 50.93  ? 300 GLN C NE2 1 
ATOM   9504  N N   . LEU C 1 301 ? 22.688  26.817  69.570  1.00 67.04  ? 301 LEU C N   1 
ATOM   9505  C CA  . LEU C 1 301 ? 23.535  27.903  69.097  1.00 68.86  ? 301 LEU C CA  1 
ATOM   9506  C C   . LEU C 1 301 ? 24.967  27.725  69.599  1.00 70.85  ? 301 LEU C C   1 
ATOM   9507  O O   . LEU C 1 301 ? 25.893  28.257  68.998  1.00 81.83  ? 301 LEU C O   1 
ATOM   9508  C CB  . LEU C 1 301 ? 22.986  29.277  69.494  1.00 66.01  ? 301 LEU C CB  1 
ATOM   9509  C CG  . LEU C 1 301 ? 23.776  30.501  69.004  1.00 59.14  ? 301 LEU C CG  1 
ATOM   9510  C CD1 . LEU C 1 301 ? 23.765  30.631  67.486  1.00 61.92  ? 301 LEU C CD1 1 
ATOM   9511  C CD2 . LEU C 1 301 ? 23.259  31.770  69.628  1.00 55.10  ? 301 LEU C CD2 1 
ATOM   9512  N N   . GLU C 1 302 ? 25.153  27.023  70.720  1.00 76.34  ? 302 GLU C N   1 
ATOM   9513  C CA  . GLU C 1 302 ? 26.492  26.701  71.186  1.00 69.90  ? 302 GLU C CA  1 
ATOM   9514  C C   . GLU C 1 302 ? 27.094  25.620  70.294  1.00 61.91  ? 302 GLU C C   1 
ATOM   9515  O O   . GLU C 1 302 ? 28.263  25.696  69.931  1.00 58.10  ? 302 GLU C O   1 
ATOM   9516  C CB  . GLU C 1 302 ? 26.493  26.279  72.652  1.00 76.72  ? 302 GLU C CB  1 
ATOM   9517  C CG  . GLU C 1 302 ? 26.880  27.420  73.583  1.00 82.33  ? 302 GLU C CG  1 
ATOM   9518  C CD  . GLU C 1 302 ? 26.808  27.023  75.038  1.00 90.15  ? 302 GLU C CD  1 
ATOM   9519  O OE1 . GLU C 1 302 ? 27.427  26.005  75.429  1.00 91.60  ? 302 GLU C OE1 1 
ATOM   9520  O OE2 . GLU C 1 302 ? 26.103  27.749  75.763  1.00 88.76  ? 302 GLU C OE2 1 
ATOM   9521  N N   . ARG C 1 303 ? 26.275  24.630  69.940  1.00 58.09  ? 303 ARG C N   1 
ATOM   9522  C CA  . ARG C 1 303 ? 26.717  23.506  69.133  1.00 72.58  ? 303 ARG C CA  1 
ATOM   9523  C C   . ARG C 1 303 ? 27.157  23.996  67.754  1.00 73.01  ? 303 ARG C C   1 
ATOM   9524  O O   . ARG C 1 303 ? 28.143  23.494  67.218  1.00 70.06  ? 303 ARG C O   1 
ATOM   9525  C CB  . ARG C 1 303 ? 25.591  22.466  69.047  1.00 84.83  ? 303 ARG C CB  1 
ATOM   9526  C CG  . ARG C 1 303 ? 25.984  21.078  68.555  1.00 94.65  ? 303 ARG C CG  1 
ATOM   9527  C CD  . ARG C 1 303 ? 25.029  19.982  69.050  1.00 104.41 ? 303 ARG C CD  1 
ATOM   9528  N NE  . ARG C 1 303 ? 23.601  20.227  68.783  1.00 112.47 ? 303 ARG C NE  1 
ATOM   9529  C CZ  . ARG C 1 303 ? 22.643  20.450  69.696  1.00 104.88 ? 303 ARG C CZ  1 
ATOM   9530  N NH1 . ARG C 1 303 ? 22.947  20.533  70.981  1.00 108.64 ? 303 ARG C NH1 1 
ATOM   9531  N NH2 . ARG C 1 303 ? 21.383  20.614  69.323  1.00 90.22  ? 303 ARG C NH2 1 
ATOM   9532  N N   . PHE C 1 304 ? 26.426  24.981  67.203  1.00 68.88  ? 304 PHE C N   1 
ATOM   9533  C CA  . PHE C 1 304 ? 26.714  25.537  65.889  1.00 60.66  ? 304 PHE C CA  1 
ATOM   9534  C C   . PHE C 1 304 ? 27.986  26.388  65.916  1.00 56.54  ? 304 PHE C C   1 
ATOM   9535  O O   . PHE C 1 304 ? 28.833  26.271  65.032  1.00 52.86  ? 304 PHE C O   1 
ATOM   9536  C CB  . PHE C 1 304 ? 25.552  26.384  65.363  1.00 59.51  ? 304 PHE C CB  1 
ATOM   9537  C CG  . PHE C 1 304 ? 25.742  26.783  63.904  1.00 60.03  ? 304 PHE C CG  1 
ATOM   9538  C CD1 . PHE C 1 304 ? 25.270  25.972  62.872  1.00 57.64  ? 304 PHE C CD1 1 
ATOM   9539  C CD2 . PHE C 1 304 ? 26.436  27.945  63.569  1.00 60.81  ? 304 PHE C CD2 1 
ATOM   9540  C CE1 . PHE C 1 304 ? 25.474  26.323  61.543  1.00 60.31  ? 304 PHE C CE1 1 
ATOM   9541  C CE2 . PHE C 1 304 ? 26.641  28.288  62.237  1.00 61.67  ? 304 PHE C CE2 1 
ATOM   9542  C CZ  . PHE C 1 304 ? 26.157  27.482  61.228  1.00 61.22  ? 304 PHE C CZ  1 
ATOM   9543  N N   . ALA C 1 305 ? 28.107  27.260  66.921  1.00 52.64  ? 305 ALA C N   1 
ATOM   9544  C CA  . ALA C 1 305 ? 29.288  28.091  67.092  1.00 56.31  ? 305 ALA C CA  1 
ATOM   9545  C C   . ALA C 1 305 ? 30.542  27.237  67.247  1.00 59.79  ? 305 ALA C C   1 
ATOM   9546  O O   . ALA C 1 305 ? 31.583  27.600  66.719  1.00 63.07  ? 305 ALA C O   1 
ATOM   9547  C CB  . ALA C 1 305 ? 29.114  28.999  68.283  1.00 59.26  ? 305 ALA C CB  1 
ATOM   9548  N N   . TRP C 1 306 ? 30.443  26.126  67.992  1.00 65.94  ? 306 TRP C N   1 
ATOM   9549  C CA  . TRP C 1 306 ? 31.581  25.241  68.176  1.00 71.12  ? 306 TRP C CA  1 
ATOM   9550  C C   . TRP C 1 306 ? 31.968  24.614  66.844  1.00 61.38  ? 306 TRP C C   1 
ATOM   9551  O O   . TRP C 1 306 ? 33.140  24.643  66.497  1.00 56.09  ? 306 TRP C O   1 
ATOM   9552  C CB  . TRP C 1 306 ? 31.349  24.187  69.274  1.00 85.25  ? 306 TRP C CB  1 
ATOM   9553  C CG  . TRP C 1 306 ? 31.833  24.691  70.608  1.00 100.68 ? 306 TRP C CG  1 
ATOM   9554  C CD1 . TRP C 1 306 ? 31.097  25.337  71.560  1.00 113.98 ? 306 TRP C CD1 1 
ATOM   9555  C CD2 . TRP C 1 306 ? 33.200  24.695  71.079  1.00 105.46 ? 306 TRP C CD2 1 
ATOM   9556  N NE1 . TRP C 1 306 ? 31.898  25.714  72.605  1.00 116.41 ? 306 TRP C NE1 1 
ATOM   9557  C CE2 . TRP C 1 306 ? 33.192  25.343  72.335  1.00 115.52 ? 306 TRP C CE2 1 
ATOM   9558  C CE3 . TRP C 1 306 ? 34.414  24.209  70.575  1.00 97.04  ? 306 TRP C CE3 1 
ATOM   9559  C CZ2 . TRP C 1 306 ? 34.354  25.513  73.085  1.00 114.93 ? 306 TRP C CZ2 1 
ATOM   9560  C CZ3 . TRP C 1 306 ? 35.559  24.382  71.320  1.00 95.34  ? 306 TRP C CZ3 1 
ATOM   9561  C CH2 . TRP C 1 306 ? 35.531  25.043  72.547  1.00 102.59 ? 306 TRP C CH2 1 
ATOM   9562  N N   . ASP C 1 307 ? 30.991  24.101  66.091  1.00 61.06  ? 307 ASP C N   1 
ATOM   9563  C CA  . ASP C 1 307 ? 31.268  23.515  64.783  1.00 65.66  ? 307 ASP C CA  1 
ATOM   9564  C C   . ASP C 1 307 ? 31.802  24.550  63.790  1.00 65.83  ? 307 ASP C C   1 
ATOM   9565  O O   . ASP C 1 307 ? 32.585  24.198  62.918  1.00 77.32  ? 307 ASP C O   1 
ATOM   9566  C CB  . ASP C 1 307 ? 30.060  22.833  64.164  1.00 60.54  ? 307 ASP C CB  1 
ATOM   9567  C CG  . ASP C 1 307 ? 29.505  21.654  64.944  1.00 64.54  ? 307 ASP C CG  1 
ATOM   9568  O OD1 . ASP C 1 307 ? 29.987  21.410  66.085  1.00 60.13  ? 307 ASP C OD1 1 
ATOM   9569  O OD2 . ASP C 1 307 ? 28.592  20.996  64.398  1.00 65.52  ? 307 ASP C OD2 1 
ATOM   9570  N N   . THR C 1 308 ? 31.373  25.812  63.889  1.00 60.09  ? 308 THR C N   1 
ATOM   9571  C CA  . THR C 1 308 ? 31.877  26.814  62.965  1.00 63.66  ? 308 THR C CA  1 
ATOM   9572  C C   . THR C 1 308 ? 33.378  26.981  63.216  1.00 60.72  ? 308 THR C C   1 
ATOM   9573  O O   . THR C 1 308 ? 34.183  26.831  62.292  1.00 54.58  ? 308 THR C O   1 
ATOM   9574  C CB  . THR C 1 308 ? 31.093  28.124  63.105  1.00 63.70  ? 308 THR C CB  1 
ATOM   9575  O OG1 . THR C 1 308 ? 29.744  27.856  62.742  1.00 60.34  ? 308 THR C OG1 1 
ATOM   9576  C CG2 . THR C 1 308 ? 31.550  29.213  62.150  1.00 64.87  ? 308 THR C CG2 1 
ATOM   9577  N N   . LEU C 1 309 ? 33.734  27.235  64.483  1.00 56.28  ? 309 LEU C N   1 
ATOM   9578  C CA  . LEU C 1 309 ? 35.093  27.566  64.892  1.00 62.90  ? 309 LEU C CA  1 
ATOM   9579  C C   . LEU C 1 309 ? 36.060  26.397  64.736  1.00 62.21  ? 309 LEU C C   1 
ATOM   9580  O O   . LEU C 1 309 ? 37.261  26.617  64.605  1.00 55.06  ? 309 LEU C O   1 
ATOM   9581  C CB  . LEU C 1 309 ? 35.062  28.015  66.349  1.00 65.60  ? 309 LEU C CB  1 
ATOM   9582  C CG  . LEU C 1 309 ? 34.369  29.351  66.611  1.00 67.22  ? 309 LEU C CG  1 
ATOM   9583  C CD1 . LEU C 1 309 ? 34.170  29.500  68.111  1.00 74.68  ? 309 LEU C CD1 1 
ATOM   9584  C CD2 . LEU C 1 309 ? 35.168  30.509  66.036  1.00 61.78  ? 309 LEU C CD2 1 
ATOM   9585  N N   . ASN C 1 310 ? 35.527  25.170  64.800  1.00 68.19  ? 310 ASN C N   1 
ATOM   9586  C CA  . ASN C 1 310 ? 36.323  23.958  64.717  1.00 66.36  ? 310 ASN C CA  1 
ATOM   9587  C C   . ASN C 1 310 ? 36.607  23.580  63.266  1.00 67.68  ? 310 ASN C C   1 
ATOM   9588  O O   . ASN C 1 310 ? 37.545  22.833  63.006  1.00 79.88  ? 310 ASN C O   1 
ATOM   9589  C CB  . ASN C 1 310 ? 35.666  22.785  65.438  1.00 62.21  ? 310 ASN C CB  1 
ATOM   9590  C CG  . ASN C 1 310 ? 35.837  22.854  66.939  1.00 58.81  ? 310 ASN C CG  1 
ATOM   9591  O OD1 . ASN C 1 310 ? 36.577  23.709  67.455  1.00 49.92  ? 310 ASN C OD1 1 
ATOM   9592  N ND2 . ASN C 1 310 ? 35.136  21.972  67.645  1.00 53.41  ? 310 ASN C ND2 1 
ATOM   9593  N N   . SER C 1 311 ? 35.807  24.055  62.311  1.00 65.75  ? 311 SER C N   1 
ATOM   9594  C CA  . SER C 1 311 ? 36.213  23.910  60.921  1.00 64.93  ? 311 SER C CA  1 
ATOM   9595  C C   . SER C 1 311 ? 36.923  25.185  60.447  1.00 61.25  ? 311 SER C C   1 
ATOM   9596  O O   . SER C 1 311 ? 36.999  25.432  59.248  1.00 55.55  ? 311 SER C O   1 
ATOM   9597  C CB  . SER C 1 311 ? 35.060  23.512  60.040  1.00 61.05  ? 311 SER C CB  1 
ATOM   9598  O OG  . SER C 1 311 ? 34.118  24.567  59.974  1.00 65.14  ? 311 SER C OG  1 
ATOM   9599  N N   . GLY C 1 312 ? 37.443  25.987  61.396  1.00 62.00  ? 312 GLY C N   1 
ATOM   9600  C CA  . GLY C 1 312 ? 38.384  27.065  61.117  1.00 58.21  ? 312 GLY C CA  1 
ATOM   9601  C C   . GLY C 1 312 ? 37.722  28.311  60.526  1.00 60.03  ? 312 GLY C C   1 
ATOM   9602  O O   . GLY C 1 312 ? 38.403  29.153  59.941  1.00 59.86  ? 312 GLY C O   1 
ATOM   9603  N N   . GLN C 1 313 ? 36.399  28.437  60.697  1.00 59.61  ? 313 GLN C N   1 
ATOM   9604  C CA  . GLN C 1 313 ? 35.662  29.590  60.206  1.00 59.02  ? 313 GLN C CA  1 
ATOM   9605  C C   . GLN C 1 313 ? 35.598  30.654  61.297  1.00 61.54  ? 313 GLN C C   1 
ATOM   9606  O O   . GLN C 1 313 ? 35.901  30.401  62.465  1.00 54.61  ? 313 GLN C O   1 
ATOM   9607  C CB  . GLN C 1 313 ? 34.191  29.313  59.898  1.00 63.76  ? 313 GLN C CB  1 
ATOM   9608  C CG  . GLN C 1 313 ? 33.897  27.973  59.239  1.00 63.99  ? 313 GLN C CG  1 
ATOM   9609  C CD  . GLN C 1 313 ? 33.698  28.101  57.755  1.00 65.63  ? 313 GLN C CD  1 
ATOM   9610  O OE1 . GLN C 1 313 ? 32.590  27.925  57.245  1.00 66.13  ? 313 GLN C OE1 1 
ATOM   9611  N NE2 . GLN C 1 313 ? 34.771  28.438  57.061  1.00 73.97  ? 313 GLN C NE2 1 
ATOM   9612  N N   . VAL C 1 314 ? 35.148  31.845  60.895  1.00 69.70  ? 314 VAL C N   1 
ATOM   9613  C CA  . VAL C 1 314 ? 34.956  32.951  61.818  1.00 68.77  ? 314 VAL C CA  1 
ATOM   9614  C C   . VAL C 1 314 ? 33.459  33.091  62.106  1.00 64.92  ? 314 VAL C C   1 
ATOM   9615  O O   . VAL C 1 314 ? 32.597  32.642  61.338  1.00 58.00  ? 314 VAL C O   1 
ATOM   9616  C CB  . VAL C 1 314 ? 35.582  34.266  61.297  1.00 74.11  ? 314 VAL C CB  1 
ATOM   9617  C CG1 . VAL C 1 314 ? 37.049  34.413  61.709  1.00 66.35  ? 314 VAL C CG1 1 
ATOM   9618  C CG2 . VAL C 1 314 ? 35.422  34.426  59.782  1.00 81.99  ? 314 VAL C CG2 1 
ATOM   9619  N N   . ILE C 1 315 ? 33.174  33.674  63.273  1.00 60.22  ? 315 ILE C N   1 
ATOM   9620  C CA  . ILE C 1 315 ? 31.836  34.119  63.604  1.00 55.68  ? 315 ILE C CA  1 
ATOM   9621  C C   . ILE C 1 315 ? 31.747  35.581  63.188  1.00 48.98  ? 315 ILE C C   1 
ATOM   9622  O O   . ILE C 1 315 ? 32.528  36.418  63.658  1.00 46.25  ? 315 ILE C O   1 
ATOM   9623  C CB  . ILE C 1 315 ? 31.549  33.881  65.095  1.00 61.57  ? 315 ILE C CB  1 
ATOM   9624  C CG1 . ILE C 1 315 ? 31.310  32.407  65.343  1.00 66.37  ? 315 ILE C CG1 1 
ATOM   9625  C CG2 . ILE C 1 315 ? 30.367  34.716  65.581  1.00 63.33  ? 315 ILE C CG2 1 
ATOM   9626  C CD1 . ILE C 1 315 ? 31.401  32.016  66.799  1.00 72.05  ? 315 ILE C CD1 1 
ATOM   9627  N N   . PRO C 1 316 ? 30.854  35.922  62.234  1.00 46.27  ? 316 PRO C N   1 
ATOM   9628  C CA  . PRO C 1 316 ? 30.785  37.295  61.735  1.00 47.59  ? 316 PRO C CA  1 
ATOM   9629  C C   . PRO C 1 316 ? 30.440  38.354  62.792  1.00 47.31  ? 316 PRO C C   1 
ATOM   9630  O O   . PRO C 1 316 ? 29.548  38.197  63.627  1.00 41.39  ? 316 PRO C O   1 
ATOM   9631  C CB  . PRO C 1 316 ? 29.753  37.212  60.588  1.00 46.82  ? 316 PRO C CB  1 
ATOM   9632  C CG  . PRO C 1 316 ? 29.614  35.740  60.260  1.00 45.29  ? 316 PRO C CG  1 
ATOM   9633  C CD  . PRO C 1 316 ? 29.955  34.998  61.524  1.00 47.50  ? 316 PRO C CD  1 
ATOM   9634  N N   . GLY C 1 317 ? 31.183  39.458  62.750  1.00 49.48  ? 317 GLY C N   1 
ATOM   9635  C CA  . GLY C 1 317 ? 30.846  40.616  63.550  1.00 51.95  ? 317 GLY C CA  1 
ATOM   9636  C C   . GLY C 1 317 ? 31.378  40.490  64.968  1.00 53.01  ? 317 GLY C C   1 
ATOM   9637  O O   . GLY C 1 317 ? 31.280  41.448  65.731  1.00 51.52  ? 317 GLY C O   1 
ATOM   9638  N N   . TYR C 1 318 ? 31.958  39.326  65.298  1.00 63.67  ? 318 TYR C N   1 
ATOM   9639  C CA  . TYR C 1 318 ? 32.593  39.110  66.592  1.00 65.49  ? 318 TYR C CA  1 
ATOM   9640  C C   . TYR C 1 318 ? 34.105  38.963  66.426  1.00 68.35  ? 318 TYR C C   1 
ATOM   9641  O O   . TYR C 1 318 ? 34.574  38.380  65.454  1.00 72.62  ? 318 TYR C O   1 
ATOM   9642  C CB  . TYR C 1 318 ? 31.995  37.882  67.288  1.00 66.77  ? 318 TYR C CB  1 
ATOM   9643  C CG  . TYR C 1 318 ? 30.619  38.118  67.900  1.00 69.20  ? 318 TYR C CG  1 
ATOM   9644  C CD1 . TYR C 1 318 ? 30.469  38.682  69.168  1.00 70.74  ? 318 TYR C CD1 1 
ATOM   9645  C CD2 . TYR C 1 318 ? 29.464  37.786  67.199  1.00 70.51  ? 318 TYR C CD2 1 
ATOM   9646  C CE1 . TYR C 1 318 ? 29.211  38.901  69.716  1.00 70.31  ? 318 TYR C CE1 1 
ATOM   9647  C CE2 . TYR C 1 318 ? 28.203  38.004  67.734  1.00 69.09  ? 318 TYR C CE2 1 
ATOM   9648  C CZ  . TYR C 1 318 ? 28.077  38.558  68.995  1.00 67.52  ? 318 TYR C CZ  1 
ATOM   9649  O OH  . TYR C 1 318 ? 26.820  38.768  69.469  1.00 71.10  ? 318 TYR C OH  1 
ATOM   9650  N N   . GLY C 1 319 ? 34.856  39.515  67.388  1.00 80.62  ? 319 GLY C N   1 
ATOM   9651  C CA  . GLY C 1 319 ? 36.264  39.196  67.563  1.00 86.54  ? 319 GLY C CA  1 
ATOM   9652  C C   . GLY C 1 319 ? 37.162  39.935  66.576  1.00 96.02  ? 319 GLY C C   1 
ATOM   9653  O O   . GLY C 1 319 ? 37.803  39.318  65.728  1.00 98.34  ? 319 GLY C O   1 
ATOM   9654  N N   . HIS C 1 320 ? 37.192  41.264  66.693  1.00 102.68 ? 320 HIS C N   1 
ATOM   9655  C CA  . HIS C 1 320 ? 38.128  42.082  65.941  1.00 107.69 ? 320 HIS C CA  1 
ATOM   9656  C C   . HIS C 1 320 ? 39.126  42.664  66.945  1.00 111.48 ? 320 HIS C C   1 
ATOM   9657  O O   . HIS C 1 320 ? 38.776  42.936  68.091  1.00 106.72 ? 320 HIS C O   1 
ATOM   9658  C CB  . HIS C 1 320 ? 37.364  43.052  65.022  1.00 106.56 ? 320 HIS C CB  1 
ATOM   9659  C CG  . HIS C 1 320 ? 36.649  42.396  63.867  1.00 103.79 ? 320 HIS C CG  1 
ATOM   9660  N ND1 . HIS C 1 320 ? 36.715  42.885  62.577  1.00 96.77  ? 320 HIS C ND1 1 
ATOM   9661  C CD2 . HIS C 1 320 ? 35.870  41.294  63.795  1.00 98.06  ? 320 HIS C CD2 1 
ATOM   9662  C CE1 . HIS C 1 320 ? 36.000  42.108  61.770  1.00 90.77  ? 320 HIS C CE1 1 
ATOM   9663  N NE2 . HIS C 1 320 ? 35.473  41.138  62.489  1.00 87.11  ? 320 HIS C NE2 1 
ATOM   9664  N N   . ALA C 1 321 ? 40.376  42.841  66.499  1.00 117.52 ? 321 ALA C N   1 
ATOM   9665  C CA  . ALA C 1 321 ? 41.533  42.905  67.381  1.00 110.04 ? 321 ALA C CA  1 
ATOM   9666  C C   . ALA C 1 321 ? 41.493  44.111  68.323  1.00 114.60 ? 321 ALA C C   1 
ATOM   9667  O O   . ALA C 1 321 ? 41.705  43.936  69.519  1.00 118.95 ? 321 ALA C O   1 
ATOM   9668  C CB  . ALA C 1 321 ? 42.808  42.892  66.552  1.00 103.85 ? 321 ALA C CB  1 
ATOM   9669  N N   . VAL C 1 322 ? 41.200  45.311  67.792  1.00 125.56 ? 322 VAL C N   1 
ATOM   9670  C CA  . VAL C 1 322 ? 41.641  46.573  68.387  1.00 128.33 ? 322 VAL C CA  1 
ATOM   9671  C C   . VAL C 1 322 ? 41.026  46.780  69.779  1.00 129.64 ? 322 VAL C C   1 
ATOM   9672  O O   . VAL C 1 322 ? 41.710  47.258  70.684  1.00 119.43 ? 322 VAL C O   1 
ATOM   9673  C CB  . VAL C 1 322 ? 41.380  47.798  67.475  1.00 123.17 ? 322 VAL C CB  1 
ATOM   9674  C CG1 . VAL C 1 322 ? 41.972  49.084  68.054  1.00 116.31 ? 322 VAL C CG1 1 
ATOM   9675  C CG2 . VAL C 1 322 ? 41.906  47.592  66.057  1.00 117.80 ? 322 VAL C CG2 1 
ATOM   9676  N N   . LEU C 1 323 ? 39.737  46.444  69.950  1.00 130.15 ? 323 LEU C N   1 
ATOM   9677  C CA  . LEU C 1 323 ? 39.039  46.659  71.213  1.00 116.95 ? 323 LEU C CA  1 
ATOM   9678  C C   . LEU C 1 323 ? 39.341  45.529  72.193  1.00 121.38 ? 323 LEU C C   1 
ATOM   9679  O O   . LEU C 1 323 ? 39.934  44.513  71.830  1.00 132.14 ? 323 LEU C O   1 
ATOM   9680  C CB  . LEU C 1 323 ? 37.528  46.773  71.001  1.00 104.42 ? 323 LEU C CB  1 
ATOM   9681  C CG  . LEU C 1 323 ? 36.995  48.155  70.616  1.00 91.31  ? 323 LEU C CG  1 
ATOM   9682  C CD1 . LEU C 1 323 ? 35.490  48.154  70.794  1.00 88.58  ? 323 LEU C CD1 1 
ATOM   9683  C CD2 . LEU C 1 323 ? 37.633  49.284  71.405  1.00 85.89  ? 323 LEU C CD2 1 
ATOM   9684  N N   . ARG C 1 324 ? 38.920  45.730  73.448  1.00 114.20 ? 324 ARG C N   1 
ATOM   9685  C CA  . ARG C 1 324 ? 38.853  44.640  74.409  1.00 121.67 ? 324 ARG C CA  1 
ATOM   9686  C C   . ARG C 1 324 ? 37.526  44.660  75.175  1.00 123.08 ? 324 ARG C C   1 
ATOM   9687  O O   . ARG C 1 324 ? 37.360  43.897  76.122  1.00 124.51 ? 324 ARG C O   1 
ATOM   9688  C CB  . ARG C 1 324 ? 40.068  44.681  75.344  1.00 127.05 ? 324 ARG C CB  1 
ATOM   9689  C CG  . ARG C 1 324 ? 41.391  44.253  74.719  1.00 127.23 ? 324 ARG C CG  1 
ATOM   9690  C CD  . ARG C 1 324 ? 42.567  44.347  75.701  1.00 124.18 ? 324 ARG C CD  1 
ATOM   9691  N NE  . ARG C 1 324 ? 42.811  45.707  76.205  1.00 121.11 ? 324 ARG C NE  1 
ATOM   9692  C CZ  . ARG C 1 324 ? 44.000  46.283  76.404  1.00 119.25 ? 324 ARG C CZ  1 
ATOM   9693  N NH1 . ARG C 1 324 ? 45.118  45.581  76.306  1.00 124.27 ? 324 ARG C NH1 1 
ATOM   9694  N NH2 . ARG C 1 324 ? 44.063  47.562  76.736  1.00 104.77 ? 324 ARG C NH2 1 
ATOM   9695  N N   . VAL C 1 325 ? 36.572  45.502  74.748  1.00 118.59 ? 325 VAL C N   1 
ATOM   9696  C CA  . VAL C 1 325 ? 35.236  45.540  75.331  1.00 95.77  ? 325 VAL C CA  1 
ATOM   9697  C C   . VAL C 1 325 ? 34.203  45.473  74.204  1.00 88.43  ? 325 VAL C C   1 
ATOM   9698  O O   . VAL C 1 325 ? 34.570  45.366  73.028  1.00 82.07  ? 325 VAL C O   1 
ATOM   9699  C CB  . VAL C 1 325 ? 35.044  46.802  76.195  1.00 90.16  ? 325 VAL C CB  1 
ATOM   9700  C CG1 . VAL C 1 325 ? 36.031  46.847  77.357  1.00 85.32  ? 325 VAL C CG1 1 
ATOM   9701  C CG2 . VAL C 1 325 ? 35.119  48.070  75.354  1.00 92.35  ? 325 VAL C CG2 1 
ATOM   9702  N N   . THR C 1 326 ? 32.910  45.528  74.568  1.00 74.74  ? 326 THR C N   1 
ATOM   9703  C CA  . THR C 1 326 ? 31.853  45.570  73.567  1.00 72.01  ? 326 THR C CA  1 
ATOM   9704  C C   . THR C 1 326 ? 31.795  46.963  72.939  1.00 62.95  ? 326 THR C C   1 
ATOM   9705  O O   . THR C 1 326 ? 31.895  47.974  73.641  1.00 62.65  ? 326 THR C O   1 
ATOM   9706  C CB  . THR C 1 326 ? 30.514  45.170  74.172  1.00 73.30  ? 326 THR C CB  1 
ATOM   9707  O OG1 . THR C 1 326 ? 30.726  43.797  74.475  1.00 83.88  ? 326 THR C OG1 1 
ATOM   9708  C CG2 . THR C 1 326 ? 29.371  45.288  73.183  1.00 70.31  ? 326 THR C CG2 1 
ATOM   9709  N N   . ASP C 1 327 ? 31.650  46.987  71.606  1.00 47.68  ? 327 ASP C N   1 
ATOM   9710  C CA  . ASP C 1 327 ? 31.585  48.223  70.849  1.00 45.17  ? 327 ASP C CA  1 
ATOM   9711  C C   . ASP C 1 327 ? 30.397  49.048  71.332  1.00 46.05  ? 327 ASP C C   1 
ATOM   9712  O O   . ASP C 1 327 ? 29.259  48.584  71.250  1.00 48.37  ? 327 ASP C O   1 
ATOM   9713  C CB  . ASP C 1 327 ? 31.411  47.925  69.372  1.00 43.10  ? 327 ASP C CB  1 
ATOM   9714  C CG  . ASP C 1 327 ? 31.546  49.105  68.418  1.00 42.28  ? 327 ASP C CG  1 
ATOM   9715  O OD1 . ASP C 1 327 ? 31.835  50.251  68.873  1.00 37.07  ? 327 ASP C OD1 1 
ATOM   9716  O OD2 . ASP C 1 327 ? 31.382  48.840  67.216  1.00 41.34  ? 327 ASP C OD2 1 
ATOM   9717  N N   . PRO C 1 328 ? 30.601  50.294  71.816  1.00 38.43  ? 328 PRO C N   1 
ATOM   9718  C CA  . PRO C 1 328 ? 29.480  51.151  72.208  1.00 38.09  ? 328 PRO C CA  1 
ATOM   9719  C C   . PRO C 1 328 ? 28.450  51.310  71.085  1.00 41.23  ? 328 PRO C C   1 
ATOM   9720  O O   . PRO C 1 328 ? 27.264  51.513  71.361  1.00 39.18  ? 328 PRO C O   1 
ATOM   9721  C CB  . PRO C 1 328 ? 30.095  52.507  72.600  1.00 38.72  ? 328 PRO C CB  1 
ATOM   9722  C CG  . PRO C 1 328 ? 31.598  52.297  72.599  1.00 39.38  ? 328 PRO C CG  1 
ATOM   9723  C CD  . PRO C 1 328 ? 31.908  50.936  71.979  1.00 38.62  ? 328 PRO C CD  1 
ATOM   9724  N N   . ARG C 1 329 ? 28.921  51.202  69.825  1.00 39.95  ? 329 ARG C N   1 
ATOM   9725  C CA  . ARG C 1 329 ? 28.065  51.371  68.671  1.00 38.10  ? 329 ARG C CA  1 
ATOM   9726  C C   . ARG C 1 329 ? 27.130  50.174  68.553  1.00 35.68  ? 329 ARG C C   1 
ATOM   9727  O O   . ARG C 1 329 ? 26.030  50.290  68.014  1.00 39.19  ? 329 ARG C O   1 
ATOM   9728  C CB  . ARG C 1 329 ? 28.926  51.609  67.426  1.00 43.95  ? 329 ARG C CB  1 
ATOM   9729  C CG  . ARG C 1 329 ? 29.759  52.885  67.449  1.00 44.03  ? 329 ARG C CG  1 
ATOM   9730  C CD  . ARG C 1 329 ? 30.747  53.035  66.287  1.00 42.34  ? 329 ARG C CD  1 
ATOM   9731  N NE  . ARG C 1 329 ? 31.682  51.907  66.237  1.00 44.00  ? 329 ARG C NE  1 
ATOM   9732  C CZ  . ARG C 1 329 ? 32.323  51.486  65.159  1.00 45.52  ? 329 ARG C CZ  1 
ATOM   9733  N NH1 . ARG C 1 329 ? 32.416  52.254  64.093  1.00 45.63  ? 329 ARG C NH1 1 
ATOM   9734  N NH2 . ARG C 1 329 ? 32.912  50.309  65.163  1.00 45.58  ? 329 ARG C NH2 1 
ATOM   9735  N N   . TYR C 1 330 ? 27.586  49.012  69.014  1.00 34.89  ? 330 TYR C N   1 
ATOM   9736  C CA  . TYR C 1 330 ? 26.732  47.831  69.109  1.00 36.86  ? 330 TYR C CA  1 
ATOM   9737  C C   . TYR C 1 330 ? 25.689  48.072  70.196  1.00 37.67  ? 330 TYR C C   1 
ATOM   9738  O O   . TYR C 1 330 ? 24.496  47.797  69.986  1.00 32.12  ? 330 TYR C O   1 
ATOM   9739  C CB  . TYR C 1 330 ? 27.472  46.537  69.483  1.00 35.07  ? 330 TYR C CB  1 
ATOM   9740  C CG  . TYR C 1 330 ? 26.669  45.239  69.503  1.00 34.05  ? 330 TYR C CG  1 
ATOM   9741  C CD1 . TYR C 1 330 ? 26.518  44.470  68.365  1.00 34.65  ? 330 TYR C CD1 1 
ATOM   9742  C CD2 . TYR C 1 330 ? 26.117  44.731  70.673  1.00 36.48  ? 330 TYR C CD2 1 
ATOM   9743  C CE1 . TYR C 1 330 ? 25.827  43.263  68.379  1.00 40.47  ? 330 TYR C CE1 1 
ATOM   9744  C CE2 . TYR C 1 330 ? 25.404  43.532  70.697  1.00 36.47  ? 330 TYR C CE2 1 
ATOM   9745  C CZ  . TYR C 1 330 ? 25.272  42.774  69.550  1.00 39.67  ? 330 TYR C CZ  1 
ATOM   9746  O OH  . TYR C 1 330 ? 24.595  41.576  69.511  1.00 38.63  ? 330 TYR C OH  1 
ATOM   9747  N N   . VAL C 1 331 ? 26.170  48.572  71.351  1.00 38.55  ? 331 VAL C N   1 
ATOM   9748  C CA  . VAL C 1 331 ? 25.339  48.718  72.532  1.00 41.44  ? 331 VAL C CA  1 
ATOM   9749  C C   . VAL C 1 331 ? 24.211  49.689  72.195  1.00 42.15  ? 331 VAL C C   1 
ATOM   9750  O O   . VAL C 1 331 ? 23.046  49.347  72.370  1.00 40.79  ? 331 VAL C O   1 
ATOM   9751  C CB  . VAL C 1 331 ? 26.115  49.138  73.792  1.00 47.45  ? 331 VAL C CB  1 
ATOM   9752  C CG1 . VAL C 1 331 ? 25.202  49.306  75.007  1.00 44.16  ? 331 VAL C CG1 1 
ATOM   9753  C CG2 . VAL C 1 331 ? 27.214  48.128  74.113  1.00 50.17  ? 331 VAL C CG2 1 
ATOM   9754  N N   . ALA C 1 332 ? 24.555  50.839  71.606  1.00 40.36  ? 332 ALA C N   1 
ATOM   9755  C CA  . ALA C 1 332 ? 23.551  51.801  71.178  1.00 37.56  ? 332 ALA C CA  1 
ATOM   9756  C C   . ALA C 1 332 ? 22.452  51.158  70.345  1.00 35.84  ? 332 ALA C C   1 
ATOM   9757  O O   . ALA C 1 332 ? 21.294  51.520  70.492  1.00 39.36  ? 332 ALA C O   1 
ATOM   9758  C CB  . ALA C 1 332 ? 24.192  52.914  70.411  1.00 39.39  ? 332 ALA C CB  1 
ATOM   9759  N N   . GLN C 1 333 ? 22.800  50.226  69.463  1.00 37.20  ? 333 GLN C N   1 
ATOM   9760  C CA  . GLN C 1 333 ? 21.824  49.636  68.555  1.00 38.48  ? 333 GLN C CA  1 
ATOM   9761  C C   . GLN C 1 333 ? 21.015  48.526  69.213  1.00 37.31  ? 333 GLN C C   1 
ATOM   9762  O O   . GLN C 1 333 ? 19.903  48.252  68.790  1.00 36.40  ? 333 GLN C O   1 
ATOM   9763  C CB  . GLN C 1 333 ? 22.519  49.009  67.345  1.00 42.71  ? 333 GLN C CB  1 
ATOM   9764  C CG  . GLN C 1 333 ? 23.108  50.032  66.383  1.00 46.60  ? 333 GLN C CG  1 
ATOM   9765  C CD  . GLN C 1 333 ? 23.784  49.384  65.196  1.00 53.88  ? 333 GLN C CD  1 
ATOM   9766  O OE1 . GLN C 1 333 ? 24.996  49.147  65.209  1.00 59.65  ? 333 GLN C OE1 1 
ATOM   9767  N NE2 . GLN C 1 333 ? 23.001  49.057  64.176  1.00 50.84  ? 333 GLN C NE2 1 
ATOM   9768  N N   . ARG C 1 334 ? 21.634  47.794  70.146  1.00 44.04  ? 334 ARG C N   1 
ATOM   9769  C CA  . ARG C 1 334 ? 20.920  46.847  70.986  1.00 41.07  ? 334 ARG C CA  1 
ATOM   9770  C C   . ARG C 1 334 ? 19.840  47.603  71.747  1.00 37.62  ? 334 ARG C C   1 
ATOM   9771  O O   . ARG C 1 334 ? 18.700  47.159  71.745  1.00 30.77  ? 334 ARG C O   1 
ATOM   9772  C CB  . ARG C 1 334 ? 21.818  46.152  72.020  1.00 47.70  ? 334 ARG C CB  1 
ATOM   9773  C CG  . ARG C 1 334 ? 21.152  45.025  72.808  1.00 49.85  ? 334 ARG C CG  1 
ATOM   9774  C CD  . ARG C 1 334 ? 22.063  44.400  73.871  1.00 53.58  ? 334 ARG C CD  1 
ATOM   9775  N NE  . ARG C 1 334 ? 21.375  43.474  74.781  1.00 55.10  ? 334 ARG C NE  1 
ATOM   9776  C CZ  . ARG C 1 334 ? 20.730  42.343  74.440  1.00 58.89  ? 334 ARG C CZ  1 
ATOM   9777  N NH1 . ARG C 1 334 ? 20.677  41.906  73.190  1.00 60.04  ? 334 ARG C NH1 1 
ATOM   9778  N NH2 . ARG C 1 334 ? 20.128  41.628  75.371  1.00 58.15  ? 334 ARG C NH2 1 
ATOM   9779  N N   . ASP C 1 335 ? 20.227  48.729  72.379  1.00 35.48  ? 335 ASP C N   1 
ATOM   9780  C CA  . ASP C 1 335 ? 19.313  49.601  73.101  1.00 38.61  ? 335 ASP C CA  1 
ATOM   9781  C C   . ASP C 1 335 ? 18.095  49.943  72.244  1.00 41.10  ? 335 ASP C C   1 
ATOM   9782  O O   . ASP C 1 335 ? 16.973  50.010  72.754  1.00 42.88  ? 335 ASP C O   1 
ATOM   9783  C CB  . ASP C 1 335 ? 19.963  50.896  73.577  1.00 43.40  ? 335 ASP C CB  1 
ATOM   9784  C CG  . ASP C 1 335 ? 19.144  51.671  74.610  1.00 49.74  ? 335 ASP C CG  1 
ATOM   9785  O OD1 . ASP C 1 335 ? 18.678  51.038  75.573  1.00 48.85  ? 335 ASP C OD1 1 
ATOM   9786  O OD2 . ASP C 1 335 ? 18.976  52.902  74.476  1.00 48.95  ? 335 ASP C OD2 1 
ATOM   9787  N N   . PHE C 1 336 ? 18.330  50.172  70.945  1.00 39.54  ? 336 PHE C N   1 
ATOM   9788  C CA  . PHE C 1 336 ? 17.289  50.613  70.029  1.00 35.77  ? 336 PHE C CA  1 
ATOM   9789  C C   . PHE C 1 336 ? 16.360  49.456  69.700  1.00 35.50  ? 336 PHE C C   1 
ATOM   9790  O O   . PHE C 1 336 ? 15.157  49.642  69.656  1.00 43.54  ? 336 PHE C O   1 
ATOM   9791  C CB  . PHE C 1 336 ? 17.902  51.215  68.768  1.00 33.23  ? 336 PHE C CB  1 
ATOM   9792  C CG  . PHE C 1 336 ? 16.888  51.697  67.747  1.00 30.46  ? 336 PHE C CG  1 
ATOM   9793  C CD1 . PHE C 1 336 ? 16.229  50.793  66.927  1.00 29.11  ? 336 PHE C CD1 1 
ATOM   9794  C CD2 . PHE C 1 336 ? 16.638  53.060  67.591  1.00 32.29  ? 336 PHE C CD2 1 
ATOM   9795  C CE1 . PHE C 1 336 ? 15.289  51.234  66.019  1.00 29.65  ? 336 PHE C CE1 1 
ATOM   9796  C CE2 . PHE C 1 336 ? 15.713  53.500  66.665  1.00 30.87  ? 336 PHE C CE2 1 
ATOM   9797  C CZ  . PHE C 1 336 ? 15.036  52.585  65.887  1.00 29.64  ? 336 PHE C CZ  1 
ATOM   9798  N N   . ALA C 1 337 ? 16.918  48.279  69.443  1.00 37.49  ? 337 ALA C N   1 
ATOM   9799  C CA  . ALA C 1 337 ? 16.118  47.105  69.138  1.00 40.79  ? 337 ALA C CA  1 
ATOM   9800  C C   . ALA C 1 337 ? 15.241  46.706  70.328  1.00 40.77  ? 337 ALA C C   1 
ATOM   9801  O O   . ALA C 1 337 ? 14.097  46.299  70.131  1.00 44.46  ? 337 ALA C O   1 
ATOM   9802  C CB  . ALA C 1 337 ? 17.019  45.963  68.712  1.00 39.96  ? 337 ALA C CB  1 
ATOM   9803  N N   . LEU C 1 338 ? 15.779  46.815  71.551  1.00 42.07  ? 338 LEU C N   1 
ATOM   9804  C CA  . LEU C 1 338 ? 15.066  46.398  72.755  1.00 44.71  ? 338 LEU C CA  1 
ATOM   9805  C C   . LEU C 1 338 ? 13.839  47.292  72.929  1.00 45.74  ? 338 LEU C C   1 
ATOM   9806  O O   . LEU C 1 338 ? 12.777  46.805  73.295  1.00 45.29  ? 338 LEU C O   1 
ATOM   9807  C CB  . LEU C 1 338 ? 15.931  46.377  74.022  1.00 42.83  ? 338 LEU C CB  1 
ATOM   9808  C CG  . LEU C 1 338 ? 16.962  45.236  74.146  1.00 42.46  ? 338 LEU C CG  1 
ATOM   9809  C CD1 . LEU C 1 338 ? 17.926  45.539  75.296  1.00 39.37  ? 338 LEU C CD1 1 
ATOM   9810  C CD2 . LEU C 1 338 ? 16.389  43.813  74.281  1.00 36.22  ? 338 LEU C CD2 1 
ATOM   9811  N N   . LYS C 1 339 ? 13.987  48.573  72.576  1.00 47.51  ? 339 LYS C N   1 
ATOM   9812  C CA  . LYS C 1 339 ? 12.917  49.561  72.636  1.00 45.43  ? 339 LYS C CA  1 
ATOM   9813  C C   . LYS C 1 339 ? 11.875  49.353  71.528  1.00 44.76  ? 339 LYS C C   1 
ATOM   9814  O O   . LYS C 1 339 ? 10.684  49.435  71.796  1.00 47.68  ? 339 LYS C O   1 
ATOM   9815  C CB  . LYS C 1 339 ? 13.581  50.938  72.587  1.00 45.66  ? 339 LYS C CB  1 
ATOM   9816  C CG  . LYS C 1 339 ? 12.873  52.107  73.238  1.00 54.66  ? 339 LYS C CG  1 
ATOM   9817  C CD  . LYS C 1 339 ? 13.784  53.328  73.359  1.00 61.92  ? 339 LYS C CD  1 
ATOM   9818  C CE  . LYS C 1 339 ? 15.143  52.967  73.922  1.00 58.68  ? 339 LYS C CE  1 
ATOM   9819  N NZ  . LYS C 1 339 ? 15.866  54.135  74.430  1.00 60.57  ? 339 LYS C NZ  1 
ATOM   9820  N N   . HIS C 1 340 ? 12.269  49.086  70.275  1.00 42.83  ? 340 HIS C N   1 
ATOM   9821  C CA  . HIS C 1 340 ? 11.313  49.245  69.184  1.00 36.82  ? 340 HIS C CA  1 
ATOM   9822  C C   . HIS C 1 340 ? 11.009  47.962  68.421  1.00 37.91  ? 340 HIS C C   1 
ATOM   9823  O O   . HIS C 1 340 ? 10.067  47.945  67.636  1.00 39.31  ? 340 HIS C O   1 
ATOM   9824  C CB  . HIS C 1 340 ? 11.759  50.301  68.173  1.00 37.63  ? 340 HIS C CB  1 
ATOM   9825  C CG  . HIS C 1 340 ? 12.155  51.616  68.752  1.00 39.03  ? 340 HIS C CG  1 
ATOM   9826  N ND1 . HIS C 1 340 ? 11.251  52.510  69.284  1.00 41.40  ? 340 HIS C ND1 1 
ATOM   9827  C CD2 . HIS C 1 340 ? 13.359  52.178  68.881  1.00 40.28  ? 340 HIS C CD2 1 
ATOM   9828  C CE1 . HIS C 1 340 ? 11.901  53.582  69.704  1.00 45.63  ? 340 HIS C CE1 1 
ATOM   9829  N NE2 . HIS C 1 340 ? 13.186  53.411  69.458  1.00 44.54  ? 340 HIS C NE2 1 
ATOM   9830  N N   . LEU C 1 341 ? 11.759  46.879  68.629  1.00 43.55  ? 341 LEU C N   1 
ATOM   9831  C CA  . LEU C 1 341 ? 11.460  45.642  67.913  1.00 46.54  ? 341 LEU C CA  1 
ATOM   9832  C C   . LEU C 1 341 ? 11.959  44.434  68.708  1.00 50.77  ? 341 LEU C C   1 
ATOM   9833  O O   . LEU C 1 341 ? 12.707  43.623  68.183  1.00 53.53  ? 341 LEU C O   1 
ATOM   9834  C CB  . LEU C 1 341 ? 12.084  45.682  66.514  1.00 43.45  ? 341 LEU C CB  1 
ATOM   9835  C CG  . LEU C 1 341 ? 13.599  45.950  66.488  1.00 38.73  ? 341 LEU C CG  1 
ATOM   9836  C CD1 . LEU C 1 341 ? 14.331  44.946  65.622  1.00 36.02  ? 341 LEU C CD1 1 
ATOM   9837  C CD2 . LEU C 1 341 ? 13.921  47.368  66.053  1.00 37.35  ? 341 LEU C CD2 1 
ATOM   9838  N N   . PRO C 1 342 ? 11.524  44.220  69.967  1.00 54.32  ? 342 PRO C N   1 
ATOM   9839  C CA  . PRO C 1 342 ? 12.136  43.194  70.804  1.00 52.18  ? 342 PRO C CA  1 
ATOM   9840  C C   . PRO C 1 342 ? 11.698  41.800  70.380  1.00 46.54  ? 342 PRO C C   1 
ATOM   9841  O O   . PRO C 1 342 ? 12.424  40.843  70.624  1.00 54.28  ? 342 PRO C O   1 
ATOM   9842  C CB  . PRO C 1 342 ? 11.646  43.566  72.190  1.00 56.62  ? 342 PRO C CB  1 
ATOM   9843  C CG  . PRO C 1 342 ? 10.255  44.091  71.911  1.00 60.85  ? 342 PRO C CG  1 
ATOM   9844  C CD  . PRO C 1 342 ? 10.380  44.877  70.616  1.00 61.14  ? 342 PRO C CD  1 
ATOM   9845  N N   . ASP C 1 343 ? 10.547  41.707  69.709  1.00 45.81  ? 343 ASP C N   1 
ATOM   9846  C CA  . ASP C 1 343 ? 9.960   40.420  69.357  1.00 50.61  ? 343 ASP C CA  1 
ATOM   9847  C C   . ASP C 1 343 ? 10.258  40.077  67.893  1.00 52.42  ? 343 ASP C C   1 
ATOM   9848  O O   . ASP C 1 343 ? 9.551   39.277  67.282  1.00 54.81  ? 343 ASP C O   1 
ATOM   9849  C CB  . ASP C 1 343 ? 8.456   40.376  69.644  1.00 52.58  ? 343 ASP C CB  1 
ATOM   9850  C CG  . ASP C 1 343 ? 7.981   40.757  71.048  1.00 56.53  ? 343 ASP C CG  1 
ATOM   9851  O OD1 . ASP C 1 343 ? 8.470   40.164  72.034  1.00 54.17  ? 343 ASP C OD1 1 
ATOM   9852  O OD2 . ASP C 1 343 ? 7.095   41.636  71.162  1.00 60.76  ? 343 ASP C OD2 1 
ATOM   9853  N N   . ASP C 1 344 ? 11.280  40.708  67.302  1.00 56.75  ? 344 ASP C N   1 
ATOM   9854  C CA  . ASP C 1 344 ? 11.671  40.401  65.932  1.00 53.84  ? 344 ASP C CA  1 
ATOM   9855  C C   . ASP C 1 344 ? 12.561  39.158  65.963  1.00 46.69  ? 344 ASP C C   1 
ATOM   9856  O O   . ASP C 1 344 ? 13.501  39.073  66.750  1.00 34.69  ? 344 ASP C O   1 
ATOM   9857  C CB  . ASP C 1 344 ? 12.294  41.601  65.228  1.00 54.44  ? 344 ASP C CB  1 
ATOM   9858  C CG  . ASP C 1 344 ? 12.803  41.337  63.816  1.00 54.28  ? 344 ASP C CG  1 
ATOM   9859  O OD1 . ASP C 1 344 ? 13.850  40.660  63.706  1.00 53.75  ? 344 ASP C OD1 1 
ATOM   9860  O OD2 . ASP C 1 344 ? 12.142  41.789  62.846  1.00 48.46  ? 344 ASP C OD2 1 
ATOM   9861  N N   . GLU C 1 345 ? 12.234  38.180  65.119  1.00 44.34  ? 345 GLU C N   1 
ATOM   9862  C CA  . GLU C 1 345 ? 12.868  36.881  65.209  1.00 45.75  ? 345 GLU C CA  1 
ATOM   9863  C C   . GLU C 1 345 ? 14.366  37.040  64.976  1.00 46.90  ? 345 GLU C C   1 
ATOM   9864  O O   . GLU C 1 345 ? 15.170  36.612  65.803  1.00 52.87  ? 345 GLU C O   1 
ATOM   9865  C CB  . GLU C 1 345 ? 12.160  35.897  64.281  1.00 48.77  ? 345 GLU C CB  1 
ATOM   9866  C CG  . GLU C 1 345 ? 10.727  35.628  64.712  1.00 50.19  ? 345 GLU C CG  1 
ATOM   9867  C CD  . GLU C 1 345 ? 10.389  34.153  64.762  1.00 62.24  ? 345 GLU C CD  1 
ATOM   9868  O OE1 . GLU C 1 345 ? 10.356  33.579  65.888  1.00 66.42  ? 345 GLU C OE1 1 
ATOM   9869  O OE2 . GLU C 1 345 ? 10.129  33.594  63.672  1.00 61.97  ? 345 GLU C OE2 1 
ATOM   9870  N N   . LEU C 1 346 ? 14.743  37.713  63.883  1.00 46.42  ? 346 LEU C N   1 
ATOM   9871  C CA  . LEU C 1 346 ? 16.150  37.832  63.533  1.00 42.33  ? 346 LEU C CA  1 
ATOM   9872  C C   . LEU C 1 346 ? 16.899  38.604  64.615  1.00 41.10  ? 346 LEU C C   1 
ATOM   9873  O O   . LEU C 1 346 ? 18.088  38.377  64.844  1.00 43.46  ? 346 LEU C O   1 
ATOM   9874  C CB  . LEU C 1 346 ? 16.331  38.456  62.148  1.00 43.70  ? 346 LEU C CB  1 
ATOM   9875  C CG  . LEU C 1 346 ? 15.723  37.679  60.975  1.00 43.24  ? 346 LEU C CG  1 
ATOM   9876  C CD1 . LEU C 1 346 ? 16.099  38.243  59.622  1.00 46.18  ? 346 LEU C CD1 1 
ATOM   9877  C CD2 . LEU C 1 346 ? 16.108  36.219  61.020  1.00 47.16  ? 346 LEU C CD2 1 
ATOM   9878  N N   . PHE C 1 347 ? 16.225  39.528  65.293  1.00 42.57  ? 347 PHE C N   1 
ATOM   9879  C CA  . PHE C 1 347 ? 16.896  40.267  66.351  1.00 42.18  ? 347 PHE C CA  1 
ATOM   9880  C C   . PHE C 1 347 ? 17.070  39.381  67.587  1.00 46.67  ? 347 PHE C C   1 
ATOM   9881  O O   . PHE C 1 347 ? 18.055  39.529  68.310  1.00 41.06  ? 347 PHE C O   1 
ATOM   9882  C CB  . PHE C 1 347 ? 16.171  41.550  66.737  1.00 38.34  ? 347 PHE C CB  1 
ATOM   9883  C CG  . PHE C 1 347 ? 16.643  42.029  68.094  1.00 39.82  ? 347 PHE C CG  1 
ATOM   9884  C CD1 . PHE C 1 347 ? 17.909  42.561  68.253  1.00 41.38  ? 347 PHE C CD1 1 
ATOM   9885  C CD2 . PHE C 1 347 ? 15.820  41.937  69.207  1.00 48.09  ? 347 PHE C CD2 1 
ATOM   9886  C CE1 . PHE C 1 347 ? 18.338  43.009  69.493  1.00 44.95  ? 347 PHE C CE1 1 
ATOM   9887  C CE2 . PHE C 1 347 ? 16.249  42.395  70.448  1.00 52.03  ? 347 PHE C CE2 1 
ATOM   9888  C CZ  . PHE C 1 347 ? 17.512  42.916  70.591  1.00 47.47  ? 347 PHE C CZ  1 
ATOM   9889  N N   . LYS C 1 348 ? 16.116  38.458  67.814  1.00 54.47  ? 348 LYS C N   1 
ATOM   9890  C CA  . LYS C 1 348 ? 16.194  37.511  68.922  1.00 58.01  ? 348 LYS C CA  1 
ATOM   9891  C C   . LYS C 1 348 ? 17.476  36.689  68.790  1.00 52.75  ? 348 LYS C C   1 
ATOM   9892  O O   . LYS C 1 348 ? 18.186  36.524  69.779  1.00 51.59  ? 348 LYS C O   1 
ATOM   9893  C CB  . LYS C 1 348 ? 14.970  36.590  69.057  1.00 61.83  ? 348 LYS C CB  1 
ATOM   9894  C CG  . LYS C 1 348 ? 13.685  37.283  69.498  1.00 68.88  ? 348 LYS C CG  1 
ATOM   9895  C CD  . LYS C 1 348 ? 12.794  36.571  70.515  1.00 72.00  ? 348 LYS C CD  1 
ATOM   9896  C CE  . LYS C 1 348 ? 12.860  37.310  71.825  1.00 78.78  ? 348 LYS C CE  1 
ATOM   9897  N NZ  . LYS C 1 348 ? 11.694  37.023  72.652  1.00 85.70  ? 348 LYS C NZ  1 
ATOM   9898  N N   . ILE C 1 349 ? 17.762  36.209  67.569  1.00 46.80  ? 349 ILE C N   1 
ATOM   9899  C CA  . ILE C 1 349 ? 19.002  35.504  67.273  1.00 42.38  ? 349 ILE C CA  1 
ATOM   9900  C C   . ILE C 1 349 ? 20.224  36.371  67.572  1.00 40.52  ? 349 ILE C C   1 
ATOM   9901  O O   . ILE C 1 349 ? 21.182  35.881  68.163  1.00 46.67  ? 349 ILE C O   1 
ATOM   9902  C CB  . ILE C 1 349 ? 19.048  35.023  65.820  1.00 42.05  ? 349 ILE C CB  1 
ATOM   9903  C CG1 . ILE C 1 349 ? 17.852  34.159  65.469  1.00 42.13  ? 349 ILE C CG1 1 
ATOM   9904  C CG2 . ILE C 1 349 ? 20.375  34.306  65.566  1.00 45.04  ? 349 ILE C CG2 1 
ATOM   9905  C CD1 . ILE C 1 349 ? 17.937  33.518  64.097  1.00 42.73  ? 349 ILE C CD1 1 
ATOM   9906  N N   . VAL C 1 350 ? 20.204  37.643  67.152  1.00 39.80  ? 350 VAL C N   1 
ATOM   9907  C CA  . VAL C 1 350 ? 21.288  38.572  67.454  1.00 40.13  ? 350 VAL C CA  1 
ATOM   9908  C C   . VAL C 1 350 ? 21.446  38.730  68.975  1.00 43.51  ? 350 VAL C C   1 
ATOM   9909  O O   . VAL C 1 350 ? 22.556  38.941  69.469  1.00 42.77  ? 350 VAL C O   1 
ATOM   9910  C CB  . VAL C 1 350 ? 21.046  39.928  66.754  1.00 38.79  ? 350 VAL C CB  1 
ATOM   9911  C CG1 . VAL C 1 350 ? 21.966  41.047  67.235  1.00 38.05  ? 350 VAL C CG1 1 
ATOM   9912  C CG2 . VAL C 1 350 ? 21.152  39.798  65.246  1.00 41.74  ? 350 VAL C CG2 1 
ATOM   9913  N N   . SER C 1 351 ? 20.321  38.680  69.706  1.00 47.72  ? 351 SER C N   1 
ATOM   9914  C CA  . SER C 1 351 ? 20.314  38.837  71.154  1.00 45.91  ? 351 SER C CA  1 
ATOM   9915  C C   . SER C 1 351 ? 20.882  37.579  71.809  1.00 46.43  ? 351 SER C C   1 
ATOM   9916  O O   . SER C 1 351 ? 21.723  37.657  72.716  1.00 42.32  ? 351 SER C O   1 
ATOM   9917  C CB  . SER C 1 351 ? 18.935  39.130  71.677  1.00 43.57  ? 351 SER C CB  1 
ATOM   9918  O OG  . SER C 1 351 ? 19.020  39.674  72.987  1.00 48.07  ? 351 SER C OG  1 
ATOM   9919  N N   . LEU C 1 352 ? 20.420  36.421  71.319  1.00 46.60  ? 352 LEU C N   1 
ATOM   9920  C CA  . LEU C 1 352 ? 20.952  35.136  71.751  1.00 51.30  ? 352 LEU C CA  1 
ATOM   9921  C C   . LEU C 1 352 ? 22.464  35.123  71.505  1.00 49.77  ? 352 LEU C C   1 
ATOM   9922  O O   . LEU C 1 352 ? 23.233  34.759  72.396  1.00 48.22  ? 352 LEU C O   1 
ATOM   9923  C CB  . LEU C 1 352 ? 20.218  33.995  71.041  1.00 51.95  ? 352 LEU C CB  1 
ATOM   9924  C CG  . LEU C 1 352 ? 20.285  32.620  71.718  1.00 55.91  ? 352 LEU C CG  1 
ATOM   9925  C CD1 . LEU C 1 352 ? 19.700  32.666  73.129  1.00 64.28  ? 352 LEU C CD1 1 
ATOM   9926  C CD2 . LEU C 1 352 ? 19.585  31.543  70.909  1.00 50.73  ? 352 LEU C CD2 1 
ATOM   9927  N N   . CYS C 1 353 ? 22.895  35.621  70.333  1.00 49.84  ? 353 CYS C N   1 
ATOM   9928  C CA  . CYS C 1 353 ? 24.314  35.633  69.999  1.00 48.82  ? 353 CYS C CA  1 
ATOM   9929  C C   . CYS C 1 353 ? 25.091  36.419  71.045  1.00 42.33  ? 353 CYS C C   1 
ATOM   9930  O O   . CYS C 1 353 ? 26.109  35.939  71.517  1.00 43.11  ? 353 CYS C O   1 
ATOM   9931  C CB  . CYS C 1 353 ? 24.589  36.091  68.568  1.00 49.96  ? 353 CYS C CB  1 
ATOM   9932  S SG  . CYS C 1 353 ? 24.258  34.809  67.322  1.00 46.92  ? 353 CYS C SG  1 
ATOM   9933  N N   . TYR C 1 354 ? 24.596  37.597  71.446  1.00 45.42  ? 354 TYR C N   1 
ATOM   9934  C CA  . TYR C 1 354 ? 25.333  38.457  72.375  1.00 43.01  ? 354 TYR C CA  1 
ATOM   9935  C C   . TYR C 1 354 ? 25.555  37.735  73.706  1.00 48.12  ? 354 TYR C C   1 
ATOM   9936  O O   . TYR C 1 354 ? 26.464  38.079  74.453  1.00 49.00  ? 354 TYR C O   1 
ATOM   9937  C CB  . TYR C 1 354 ? 24.570  39.747  72.674  1.00 35.03  ? 354 TYR C CB  1 
ATOM   9938  C CG  . TYR C 1 354 ? 25.296  40.852  73.430  1.00 33.59  ? 354 TYR C CG  1 
ATOM   9939  C CD1 . TYR C 1 354 ? 26.637  41.134  73.216  1.00 34.14  ? 354 TYR C CD1 1 
ATOM   9940  C CD2 . TYR C 1 354 ? 24.612  41.675  74.322  1.00 35.65  ? 354 TYR C CD2 1 
ATOM   9941  C CE1 . TYR C 1 354 ? 27.271  42.200  73.848  1.00 35.43  ? 354 TYR C CE1 1 
ATOM   9942  C CE2 . TYR C 1 354 ? 25.235  42.734  74.975  1.00 35.37  ? 354 TYR C CE2 1 
ATOM   9943  C CZ  . TYR C 1 354 ? 26.571  43.002  74.735  1.00 36.31  ? 354 TYR C CZ  1 
ATOM   9944  O OH  . TYR C 1 354 ? 27.195  44.046  75.363  1.00 35.62  ? 354 TYR C OH  1 
ATOM   9945  N N   . GLU C 1 355 ? 24.681  36.775  74.018  1.00 50.77  ? 355 GLU C N   1 
ATOM   9946  C CA  . GLU C 1 355 ? 24.795  36.033  75.255  1.00 65.04  ? 355 GLU C CA  1 
ATOM   9947  C C   . GLU C 1 355 ? 25.785  34.887  75.057  1.00 59.99  ? 355 GLU C C   1 
ATOM   9948  O O   . GLU C 1 355 ? 26.736  34.771  75.821  1.00 53.72  ? 355 GLU C O   1 
ATOM   9949  C CB  . GLU C 1 355 ? 23.425  35.531  75.710  1.00 76.90  ? 355 GLU C CB  1 
ATOM   9950  C CG  . GLU C 1 355 ? 23.447  34.987  77.133  1.00 83.94  ? 355 GLU C CG  1 
ATOM   9951  C CD  . GLU C 1 355 ? 22.242  34.158  77.515  1.00 87.40  ? 355 GLU C CD  1 
ATOM   9952  O OE1 . GLU C 1 355 ? 22.243  33.719  78.687  1.00 87.63  ? 355 GLU C OE1 1 
ATOM   9953  O OE2 . GLU C 1 355 ? 21.347  33.937  76.665  1.00 79.48  ? 355 GLU C OE2 1 
ATOM   9954  N N   . VAL C 1 356 ? 25.564  34.084  74.009  1.00 52.85  ? 356 VAL C N   1 
ATOM   9955  C CA  . VAL C 1 356 ? 26.256  32.820  73.814  1.00 53.43  ? 356 VAL C CA  1 
ATOM   9956  C C   . VAL C 1 356 ? 27.693  32.999  73.321  1.00 61.67  ? 356 VAL C C   1 
ATOM   9957  O O   . VAL C 1 356 ? 28.624  32.477  73.953  1.00 57.37  ? 356 VAL C O   1 
ATOM   9958  C CB  . VAL C 1 356 ? 25.440  31.996  72.809  1.00 58.02  ? 356 VAL C CB  1 
ATOM   9959  C CG1 . VAL C 1 356 ? 26.211  30.775  72.322  1.00 59.39  ? 356 VAL C CG1 1 
ATOM   9960  C CG2 . VAL C 1 356 ? 24.087  31.618  73.393  1.00 59.12  ? 356 VAL C CG2 1 
ATOM   9961  N N   . ILE C 1 357 ? 27.845  33.741  72.201  1.00 59.35  ? 357 ILE C N   1 
ATOM   9962  C CA  . ILE C 1 357 ? 29.029  33.723  71.344  1.00 56.77  ? 357 ILE C CA  1 
ATOM   9963  C C   . ILE C 1 357 ? 30.304  34.127  72.096  1.00 56.02  ? 357 ILE C C   1 
ATOM   9964  O O   . ILE C 1 357 ? 31.319  33.450  71.953  1.00 61.14  ? 357 ILE C O   1 
ATOM   9965  C CB  . ILE C 1 357 ? 28.810  34.569  70.069  1.00 55.83  ? 357 ILE C CB  1 
ATOM   9966  C CG1 . ILE C 1 357 ? 27.706  33.994  69.149  1.00 50.99  ? 357 ILE C CG1 1 
ATOM   9967  C CG2 . ILE C 1 357 ? 30.117  34.796  69.302  1.00 56.48  ? 357 ILE C CG2 1 
ATOM   9968  C CD1 . ILE C 1 357 ? 27.893  32.559  68.699  1.00 50.60  ? 357 ILE C CD1 1 
ATOM   9969  N N   . PRO C 1 358 ? 30.352  35.226  72.888  1.00 59.01  ? 358 PRO C N   1 
ATOM   9970  C CA  . PRO C 1 358 ? 31.570  35.558  73.638  1.00 60.92  ? 358 PRO C CA  1 
ATOM   9971  C C   . PRO C 1 358 ? 31.986  34.522  74.694  1.00 69.83  ? 358 PRO C C   1 
ATOM   9972  O O   . PRO C 1 358 ? 33.143  34.490  75.117  1.00 70.97  ? 358 PRO C O   1 
ATOM   9973  C CB  . PRO C 1 358 ? 31.241  36.929  74.274  1.00 55.95  ? 358 PRO C CB  1 
ATOM   9974  C CG  . PRO C 1 358 ? 30.012  37.428  73.550  1.00 52.37  ? 358 PRO C CG  1 
ATOM   9975  C CD  . PRO C 1 358 ? 29.267  36.198  73.096  1.00 54.43  ? 358 PRO C CD  1 
ATOM   9976  N N   . GLU C 1 359 ? 31.033  33.692  75.142  1.00 79.14  ? 359 GLU C N   1 
ATOM   9977  C CA  . GLU C 1 359 ? 31.315  32.615  76.085  1.00 90.62  ? 359 GLU C CA  1 
ATOM   9978  C C   . GLU C 1 359 ? 31.999  31.464  75.346  1.00 81.94  ? 359 GLU C C   1 
ATOM   9979  O O   . GLU C 1 359 ? 32.848  30.776  75.911  1.00 81.68  ? 359 GLU C O   1 
ATOM   9980  C CB  . GLU C 1 359 ? 30.047  32.154  76.824  1.00 93.66  ? 359 GLU C CB  1 
ATOM   9981  C CG  . GLU C 1 359 ? 29.620  33.090  77.955  1.00 89.16  ? 359 GLU C CG  1 
ATOM   9982  C CD  . GLU C 1 359 ? 30.692  33.236  79.024  1.00 93.95  ? 359 GLU C CD  1 
ATOM   9983  O OE1 . GLU C 1 359 ? 31.360  34.294  79.109  1.00 88.55  ? 359 GLU C OE1 1 
ATOM   9984  O OE2 . GLU C 1 359 ? 30.871  32.251  79.769  1.00 96.71  ? 359 GLU C OE2 1 
ATOM   9985  N N   . VAL C 1 360 ? 31.601  31.269  74.083  1.00 73.28  ? 360 VAL C N   1 
ATOM   9986  C CA  . VAL C 1 360 ? 32.205  30.292  73.198  1.00 64.02  ? 360 VAL C CA  1 
ATOM   9987  C C   . VAL C 1 360 ? 33.540  30.806  72.668  1.00 64.05  ? 360 VAL C C   1 
ATOM   9988  O O   . VAL C 1 360 ? 34.469  30.030  72.512  1.00 68.83  ? 360 VAL C O   1 
ATOM   9989  C CB  . VAL C 1 360 ? 31.259  29.948  72.042  1.00 63.27  ? 360 VAL C CB  1 
ATOM   9990  C CG1 . VAL C 1 360 ? 31.949  29.068  71.011  1.00 66.99  ? 360 VAL C CG1 1 
ATOM   9991  C CG2 . VAL C 1 360 ? 29.981  29.297  72.550  1.00 62.37  ? 360 VAL C CG2 1 
ATOM   9992  N N   . LEU C 1 361 ? 33.655  32.101  72.384  1.00 61.22  ? 361 LEU C N   1 
ATOM   9993  C CA  . LEU C 1 361 ? 34.940  32.634  71.953  1.00 69.68  ? 361 LEU C CA  1 
ATOM   9994  C C   . LEU C 1 361 ? 35.942  32.647  73.116  1.00 77.30  ? 361 LEU C C   1 
ATOM   9995  O O   . LEU C 1 361 ? 37.148  32.686  72.877  1.00 82.54  ? 361 LEU C O   1 
ATOM   9996  C CB  . LEU C 1 361 ? 34.819  34.030  71.330  1.00 67.71  ? 361 LEU C CB  1 
ATOM   9997  C CG  . LEU C 1 361 ? 34.216  34.139  69.922  1.00 63.84  ? 361 LEU C CG  1 
ATOM   9998  C CD1 . LEU C 1 361 ? 34.053  35.610  69.550  1.00 56.74  ? 361 LEU C CD1 1 
ATOM   9999  C CD2 . LEU C 1 361 ? 35.027  33.415  68.858  1.00 64.60  ? 361 LEU C CD2 1 
ATOM   10000 N N   . LYS C 1 362 ? 35.473  32.668  74.374  1.00 85.04  ? 362 LYS C N   1 
ATOM   10001 C CA  . LYS C 1 362 ? 36.394  32.716  75.505  1.00 89.30  ? 362 LYS C CA  1 
ATOM   10002 C C   . LYS C 1 362 ? 36.976  31.316  75.752  1.00 90.49  ? 362 LYS C C   1 
ATOM   10003 O O   . LYS C 1 362 ? 38.182  31.188  75.974  1.00 79.10  ? 362 LYS C O   1 
ATOM   10004 C CB  . LYS C 1 362 ? 35.760  33.388  76.735  1.00 92.38  ? 362 LYS C CB  1 
ATOM   10005 C CG  . LYS C 1 362 ? 36.055  34.886  76.937  1.00 99.22  ? 362 LYS C CG  1 
ATOM   10006 C CD  . LYS C 1 362 ? 35.298  35.590  78.071  1.00 101.86 ? 362 LYS C CD  1 
ATOM   10007 C CE  . LYS C 1 362 ? 35.882  36.933  78.492  1.00 97.13  ? 362 LYS C CE  1 
ATOM   10008 N NZ  . LYS C 1 362 ? 34.976  37.811  79.248  1.00 84.22  ? 362 LYS C NZ  1 
ATOM   10009 N N   . LYS C 1 363 ? 36.128  30.274  75.652  1.00 97.40  ? 363 LYS C N   1 
ATOM   10010 C CA  . LYS C 1 363 ? 36.490  28.891  75.960  1.00 104.17 ? 363 LYS C CA  1 
ATOM   10011 C C   . LYS C 1 363 ? 37.224  28.210  74.802  1.00 107.43 ? 363 LYS C C   1 
ATOM   10012 O O   . LYS C 1 363 ? 37.907  27.206  75.003  1.00 124.58 ? 363 LYS C O   1 
ATOM   10013 C CB  . LYS C 1 363 ? 35.245  28.055  76.282  1.00 105.22 ? 363 LYS C CB  1 
ATOM   10014 C CG  . LYS C 1 363 ? 34.677  28.275  77.675  1.00 107.17 ? 363 LYS C CG  1 
ATOM   10015 C CD  . LYS C 1 363 ? 33.207  27.896  77.801  1.00 115.81 ? 363 LYS C CD  1 
ATOM   10016 C CE  . LYS C 1 363 ? 32.562  28.518  79.006  1.00 117.15 ? 363 LYS C CE  1 
ATOM   10017 N NZ  . LYS C 1 363 ? 31.166  28.877  78.738  1.00 113.28 ? 363 LYS C NZ  1 
ATOM   10018 N N   . HIS C 1 364 ? 37.015  28.720  73.586  1.00 98.95  ? 364 HIS C N   1 
ATOM   10019 C CA  . HIS C 1 364 ? 37.823  28.390  72.422  1.00 85.27  ? 364 HIS C CA  1 
ATOM   10020 C C   . HIS C 1 364 ? 39.184  29.078  72.541  1.00 84.41  ? 364 HIS C C   1 
ATOM   10021 O O   . HIS C 1 364 ? 40.200  28.490  72.191  1.00 86.26  ? 364 HIS C O   1 
ATOM   10022 C CB  . HIS C 1 364 ? 37.050  28.812  71.171  1.00 80.19  ? 364 HIS C CB  1 
ATOM   10023 C CG  . HIS C 1 364 ? 37.515  28.240  69.890  1.00 74.48  ? 364 HIS C CG  1 
ATOM   10024 N ND1 . HIS C 1 364 ? 37.037  27.051  69.385  1.00 77.99  ? 364 HIS C ND1 1 
ATOM   10025 C CD2 . HIS C 1 364 ? 38.367  28.718  68.987  1.00 79.29  ? 364 HIS C CD2 1 
ATOM   10026 C CE1 . HIS C 1 364 ? 37.619  26.814  68.215  1.00 80.10  ? 364 HIS C CE1 1 
ATOM   10027 N NE2 . HIS C 1 364 ? 38.441  27.809  67.958  1.00 77.32  ? 364 HIS C NE2 1 
ATOM   10028 N N   . GLY C 1 365 ? 39.191  30.333  73.018  1.00 92.63  ? 365 GLY C N   1 
ATOM   10029 C CA  . GLY C 1 365 ? 40.394  31.009  73.487  1.00 101.14 ? 365 GLY C CA  1 
ATOM   10030 C C   . GLY C 1 365 ? 41.344  31.405  72.354  1.00 116.50 ? 365 GLY C C   1 
ATOM   10031 O O   . GLY C 1 365 ? 42.554  31.459  72.574  1.00 116.33 ? 365 GLY C O   1 
ATOM   10032 N N   . LYS C 1 366 ? 40.787  31.691  71.160  1.00 127.20 ? 366 LYS C N   1 
ATOM   10033 C CA  . LYS C 1 366 ? 41.555  32.064  69.972  1.00 123.88 ? 366 LYS C CA  1 
ATOM   10034 C C   . LYS C 1 366 ? 41.446  33.567  69.668  1.00 122.46 ? 366 LYS C C   1 
ATOM   10035 O O   . LYS C 1 366 ? 42.117  34.060  68.758  1.00 94.55  ? 366 LYS C O   1 
ATOM   10036 C CB  . LYS C 1 366 ? 41.090  31.303  68.717  1.00 120.71 ? 366 LYS C CB  1 
ATOM   10037 C CG  . LYS C 1 366 ? 41.277  29.775  68.646  1.00 121.73 ? 366 LYS C CG  1 
ATOM   10038 C CD  . LYS C 1 366 ? 42.694  29.209  68.613  1.00 116.54 ? 366 LYS C CD  1 
ATOM   10039 C CE  . LYS C 1 366 ? 43.110  28.639  69.936  1.00 105.36 ? 366 LYS C CE  1 
ATOM   10040 N NZ  . LYS C 1 366 ? 44.554  28.414  70.024  1.00 105.01 ? 366 LYS C NZ  1 
ATOM   10041 N N   . ALA C 1 367 ? 40.595  34.291  70.417  1.00 135.62 ? 367 ALA C N   1 
ATOM   10042 C CA  . ALA C 1 367 ? 40.361  35.715  70.209  1.00 125.31 ? 367 ALA C CA  1 
ATOM   10043 C C   . ALA C 1 367 ? 40.629  36.497  71.501  1.00 119.08 ? 367 ALA C C   1 
ATOM   10044 O O   . ALA C 1 367 ? 39.996  36.249  72.534  1.00 104.81 ? 367 ALA C O   1 
ATOM   10045 C CB  . ALA C 1 367 ? 38.944  35.916  69.705  1.00 122.08 ? 367 ALA C CB  1 
ATOM   10046 N N   . LYS C 1 368 ? 41.576  37.450  71.433  1.00 112.14 ? 368 LYS C N   1 
ATOM   10047 C CA  . LYS C 1 368 ? 41.955  38.252  72.591  1.00 108.36 ? 368 LYS C CA  1 
ATOM   10048 C C   . LYS C 1 368 ? 40.822  39.219  72.948  1.00 113.79 ? 368 LYS C C   1 
ATOM   10049 O O   . LYS C 1 368 ? 40.751  39.684  74.082  1.00 113.17 ? 368 LYS C O   1 
ATOM   10050 C CB  . LYS C 1 368 ? 43.284  38.982  72.352  1.00 91.08  ? 368 LYS C CB  1 
ATOM   10051 N N   . ASN C 1 369 ? 39.963  39.529  71.960  1.00 110.95 ? 369 ASN C N   1 
ATOM   10052 C CA  . ASN C 1 369 ? 38.696  40.219  72.159  1.00 99.73  ? 369 ASN C CA  1 
ATOM   10053 C C   . ASN C 1 369 ? 37.562  39.318  71.660  1.00 81.04  ? 369 ASN C C   1 
ATOM   10054 O O   . ASN C 1 369 ? 37.539  38.976  70.484  1.00 85.37  ? 369 ASN C O   1 
ATOM   10055 C CB  . ASN C 1 369 ? 38.690  41.558  71.422  1.00 117.10 ? 369 ASN C CB  1 
ATOM   10056 C CG  . ASN C 1 369 ? 37.343  42.253  71.426  1.00 132.19 ? 369 ASN C CG  1 
ATOM   10057 O OD1 . ASN C 1 369 ? 36.427  41.857  72.155  1.00 144.16 ? 369 ASN C OD1 1 
ATOM   10058 N ND2 . ASN C 1 369 ? 37.198  43.304  70.630  1.00 135.98 ? 369 ASN C ND2 1 
ATOM   10059 N N   . PRO C 1 370 ? 36.602  38.886  72.516  1.00 60.87  ? 370 PRO C N   1 
ATOM   10060 C CA  . PRO C 1 370 ? 35.446  38.100  72.071  1.00 56.11  ? 370 PRO C CA  1 
ATOM   10061 C C   . PRO C 1 370 ? 34.111  38.827  71.863  1.00 55.78  ? 370 PRO C C   1 
ATOM   10062 O O   . PRO C 1 370 ? 33.077  38.176  71.717  1.00 51.85  ? 370 PRO C O   1 
ATOM   10063 C CB  . PRO C 1 370 ? 35.383  37.159  73.274  1.00 53.28  ? 370 PRO C CB  1 
ATOM   10064 C CG  . PRO C 1 370 ? 35.550  38.093  74.447  1.00 56.27  ? 370 PRO C CG  1 
ATOM   10065 C CD  . PRO C 1 370 ? 36.615  39.071  73.976  1.00 58.43  ? 370 PRO C CD  1 
ATOM   10066 N N   . TRP C 1 371 ? 34.148  40.168  71.826  1.00 55.75  ? 371 TRP C N   1 
ATOM   10067 C CA  . TRP C 1 371 ? 32.956  41.003  71.852  1.00 61.18  ? 371 TRP C CA  1 
ATOM   10068 C C   . TRP C 1 371 ? 32.620  41.566  70.468  1.00 57.24  ? 371 TRP C C   1 
ATOM   10069 O O   . TRP C 1 371 ? 33.502  41.740  69.635  1.00 52.79  ? 371 TRP C O   1 
ATOM   10070 C CB  . TRP C 1 371 ? 33.178  42.145  72.844  1.00 68.46  ? 371 TRP C CB  1 
ATOM   10071 C CG  . TRP C 1 371 ? 33.310  41.705  74.278  1.00 73.04  ? 371 TRP C CG  1 
ATOM   10072 C CD1 . TRP C 1 371 ? 34.351  41.983  75.114  1.00 73.56  ? 371 TRP C CD1 1 
ATOM   10073 C CD2 . TRP C 1 371 ? 32.341  40.981  75.067  1.00 79.71  ? 371 TRP C CD2 1 
ATOM   10074 N NE1 . TRP C 1 371 ? 34.117  41.459  76.356  1.00 76.20  ? 371 TRP C NE1 1 
ATOM   10075 C CE2 . TRP C 1 371 ? 32.890  40.851  76.364  1.00 83.63  ? 371 TRP C CE2 1 
ATOM   10076 C CE3 . TRP C 1 371 ? 31.078  40.430  74.812  1.00 80.10  ? 371 TRP C CE3 1 
ATOM   10077 C CZ2 . TRP C 1 371 ? 32.220  40.197  77.397  1.00 91.20  ? 371 TRP C CZ2 1 
ATOM   10078 C CZ3 . TRP C 1 371 ? 30.410  39.795  75.842  1.00 88.39  ? 371 TRP C CZ3 1 
ATOM   10079 C CH2 . TRP C 1 371 ? 30.972  39.686  77.117  1.00 87.49  ? 371 TRP C CH2 1 
ATOM   10080 N N   . PRO C 1 372 ? 31.335  41.890  70.187  1.00 55.18  ? 372 PRO C N   1 
ATOM   10081 C CA  . PRO C 1 372 ? 30.913  42.313  68.856  1.00 51.40  ? 372 PRO C CA  1 
ATOM   10082 C C   . PRO C 1 372 ? 31.199  43.778  68.538  1.00 50.69  ? 372 PRO C C   1 
ATOM   10083 O O   . PRO C 1 372 ? 31.524  44.579  69.423  1.00 41.99  ? 372 PRO C O   1 
ATOM   10084 C CB  . PRO C 1 372 ? 29.412  42.017  68.848  1.00 54.58  ? 372 PRO C CB  1 
ATOM   10085 C CG  . PRO C 1 372 ? 28.977  42.104  70.289  1.00 55.03  ? 372 PRO C CG  1 
ATOM   10086 C CD  . PRO C 1 372 ? 30.215  41.872  71.134  1.00 60.02  ? 372 PRO C CD  1 
ATOM   10087 N N   . ASN C 1 373 ? 31.114  44.088  67.233  1.00 49.73  ? 373 ASN C N   1 
ATOM   10088 C CA  . ASN C 1 373 ? 31.256  45.453  66.751  1.00 46.77  ? 373 ASN C CA  1 
ATOM   10089 C C   . ASN C 1 373 ? 29.963  45.889  66.075  1.00 43.44  ? 373 ASN C C   1 
ATOM   10090 O O   . ASN C 1 373 ? 29.080  45.069  65.792  1.00 41.38  ? 373 ASN C O   1 
ATOM   10091 C CB  . ASN C 1 373 ? 32.442  45.648  65.808  1.00 46.94  ? 373 ASN C CB  1 
ATOM   10092 C CG  . ASN C 1 373 ? 32.361  44.821  64.541  1.00 48.61  ? 373 ASN C CG  1 
ATOM   10093 O OD1 . ASN C 1 373 ? 31.289  44.632  63.953  1.00 43.85  ? 373 ASN C OD1 1 
ATOM   10094 N ND2 . ASN C 1 373 ? 33.501  44.313  64.095  1.00 56.04  ? 373 ASN C ND2 1 
ATOM   10095 N N   . VAL C 1 374 ? 29.925  47.196  65.784  1.00 42.76  ? 374 VAL C N   1 
ATOM   10096 C CA  . VAL C 1 374 ? 28.787  47.891  65.202  1.00 42.38  ? 374 VAL C CA  1 
ATOM   10097 C C   . VAL C 1 374 ? 28.144  47.087  64.082  1.00 39.25  ? 374 VAL C C   1 
ATOM   10098 O O   . VAL C 1 374 ? 26.928  47.164  63.945  1.00 39.89  ? 374 VAL C O   1 
ATOM   10099 C CB  . VAL C 1 374 ? 29.183  49.288  64.696  1.00 45.30  ? 374 VAL C CB  1 
ATOM   10100 C CG1 . VAL C 1 374 ? 30.145  49.218  63.516  1.00 51.15  ? 374 VAL C CG1 1 
ATOM   10101 C CG2 . VAL C 1 374 ? 27.967  50.115  64.333  1.00 44.95  ? 374 VAL C CG2 1 
ATOM   10102 N N   . ASP C 1 375 ? 28.938  46.333  63.299  1.00 43.22  ? 375 ASP C N   1 
ATOM   10103 C CA  . ASP C 1 375 ? 28.424  45.655  62.105  1.00 48.19  ? 375 ASP C CA  1 
ATOM   10104 C C   . ASP C 1 375 ? 27.646  44.392  62.462  1.00 42.26  ? 375 ASP C C   1 
ATOM   10105 O O   . ASP C 1 375 ? 26.968  43.807  61.605  1.00 41.45  ? 375 ASP C O   1 
ATOM   10106 C CB  . ASP C 1 375 ? 29.499  45.401  61.055  1.00 51.91  ? 375 ASP C CB  1 
ATOM   10107 C CG  . ASP C 1 375 ? 30.300  46.628  60.647  1.00 53.72  ? 375 ASP C CG  1 
ATOM   10108 O OD1 . ASP C 1 375 ? 29.674  47.668  60.301  1.00 48.97  ? 375 ASP C OD1 1 
ATOM   10109 O OD2 . ASP C 1 375 ? 31.540  46.531  60.696  1.00 57.88  ? 375 ASP C OD2 1 
ATOM   10110 N N   . ALA C 1 376 ? 27.711  44.012  63.744  1.00 44.87  ? 376 ALA C N   1 
ATOM   10111 C CA  . ALA C 1 376 ? 26.982  42.859  64.239  1.00 43.03  ? 376 ALA C CA  1 
ATOM   10112 C C   . ALA C 1 376 ? 25.492  43.171  64.390  1.00 41.26  ? 376 ALA C C   1 
ATOM   10113 O O   . ALA C 1 376 ? 24.659  42.269  64.363  1.00 42.17  ? 376 ALA C O   1 
ATOM   10114 C CB  . ALA C 1 376 ? 27.620  42.420  65.527  1.00 46.19  ? 376 ALA C CB  1 
ATOM   10115 N N   . HIS C 1 377 ? 25.139  44.457  64.470  1.00 45.76  ? 377 HIS C N   1 
ATOM   10116 C CA  . HIS C 1 377 ? 23.780  44.818  64.827  1.00 48.36  ? 377 HIS C CA  1 
ATOM   10117 C C   . HIS C 1 377 ? 23.022  45.487  63.680  1.00 46.21  ? 377 HIS C C   1 
ATOM   10118 O O   . HIS C 1 377 ? 21.813  45.340  63.615  1.00 50.65  ? 377 HIS C O   1 
ATOM   10119 C CB  . HIS C 1 377 ? 23.782  45.641  66.122  1.00 48.25  ? 377 HIS C CB  1 
ATOM   10120 C CG  . HIS C 1 377 ? 22.661  45.271  67.030  1.00 52.39  ? 377 HIS C CG  1 
ATOM   10121 N ND1 . HIS C 1 377 ? 21.398  44.995  66.548  1.00 44.35  ? 377 HIS C ND1 1 
ATOM   10122 C CD2 . HIS C 1 377 ? 22.610  45.094  68.374  1.00 55.53  ? 377 HIS C CD2 1 
ATOM   10123 C CE1 . HIS C 1 377 ? 20.610  44.683  67.570  1.00 52.74  ? 377 HIS C CE1 1 
ATOM   10124 N NE2 . HIS C 1 377 ? 21.324  44.722  68.688  1.00 54.93  ? 377 HIS C NE2 1 
ATOM   10125 N N   . SER C 1 378 ? 23.694  46.206  62.780  1.00 50.83  ? 378 SER C N   1 
ATOM   10126 C CA  . SER C 1 378 ? 22.996  47.091  61.841  1.00 51.67  ? 378 SER C CA  1 
ATOM   10127 C C   . SER C 1 378 ? 22.062  46.343  60.886  1.00 43.12  ? 378 SER C C   1 
ATOM   10128 O O   . SER C 1 378 ? 20.948  46.777  60.625  1.00 42.51  ? 378 SER C O   1 
ATOM   10129 C CB  . SER C 1 378 ? 23.958  47.961  61.072  1.00 50.46  ? 378 SER C CB  1 
ATOM   10130 O OG  . SER C 1 378 ? 24.924  47.158  60.415  1.00 52.12  ? 378 SER C OG  1 
ATOM   10131 N N   . GLY C 1 379 ? 22.477  45.196  60.379  1.00 45.89  ? 379 GLY C N   1 
ATOM   10132 C CA  . GLY C 1 379 ? 21.705  44.538  59.334  1.00 49.48  ? 379 GLY C CA  1 
ATOM   10133 C C   . GLY C 1 379 ? 20.263  44.235  59.737  1.00 47.52  ? 379 GLY C C   1 
ATOM   10134 O O   . GLY C 1 379 ? 19.333  44.507  58.981  1.00 46.36  ? 379 GLY C O   1 
ATOM   10135 N N   . VAL C 1 380 ? 20.081  43.607  60.902  1.00 49.50  ? 380 VAL C N   1 
ATOM   10136 C CA  . VAL C 1 380 ? 18.752  43.200  61.341  1.00 45.63  ? 380 VAL C CA  1 
ATOM   10137 C C   . VAL C 1 380 ? 17.861  44.436  61.456  1.00 42.36  ? 380 VAL C C   1 
ATOM   10138 O O   . VAL C 1 380 ? 16.667  44.344  61.171  1.00 45.50  ? 380 VAL C O   1 
ATOM   10139 C CB  . VAL C 1 380 ? 18.772  42.404  62.662  1.00 47.65  ? 380 VAL C CB  1 
ATOM   10140 C CG1 . VAL C 1 380 ? 19.477  41.063  62.484  1.00 47.23  ? 380 VAL C CG1 1 
ATOM   10141 C CG2 . VAL C 1 380 ? 19.394  43.197  63.814  1.00 44.71  ? 380 VAL C CG2 1 
ATOM   10142 N N   . LEU C 1 381 ? 18.447  45.584  61.843  1.00 36.71  ? 381 LEU C N   1 
ATOM   10143 C CA  . LEU C 1 381 ? 17.688  46.812  62.027  1.00 37.71  ? 381 LEU C CA  1 
ATOM   10144 C C   . LEU C 1 381 ? 17.085  47.252  60.701  1.00 37.26  ? 381 LEU C C   1 
ATOM   10145 O O   . LEU C 1 381 ? 15.884  47.492  60.634  1.00 38.36  ? 381 LEU C O   1 
ATOM   10146 C CB  . LEU C 1 381 ? 18.497  47.940  62.669  1.00 38.04  ? 381 LEU C CB  1 
ATOM   10147 C CG  . LEU C 1 381 ? 18.938  47.682  64.118  1.00 39.82  ? 381 LEU C CG  1 
ATOM   10148 C CD1 . LEU C 1 381 ? 19.590  48.884  64.767  1.00 39.87  ? 381 LEU C CD1 1 
ATOM   10149 C CD2 . LEU C 1 381 ? 17.768  47.220  64.964  1.00 39.35  ? 381 LEU C CD2 1 
ATOM   10150 N N   . LEU C 1 382 ? 17.916  47.337  59.658  1.00 40.11  ? 382 LEU C N   1 
ATOM   10151 C CA  . LEU C 1 382 ? 17.467  47.744  58.330  1.00 37.00  ? 382 LEU C CA  1 
ATOM   10152 C C   . LEU C 1 382 ? 16.406  46.788  57.800  1.00 35.94  ? 382 LEU C C   1 
ATOM   10153 O O   . LEU C 1 382 ? 15.357  47.207  57.315  1.00 39.70  ? 382 LEU C O   1 
ATOM   10154 C CB  . LEU C 1 382 ? 18.682  47.754  57.411  1.00 36.73  ? 382 LEU C CB  1 
ATOM   10155 C CG  . LEU C 1 382 ? 19.746  48.808  57.723  1.00 35.37  ? 382 LEU C CG  1 
ATOM   10156 C CD1 . LEU C 1 382 ? 20.923  48.645  56.788  1.00 37.63  ? 382 LEU C CD1 1 
ATOM   10157 C CD2 . LEU C 1 382 ? 19.206  50.222  57.645  1.00 34.22  ? 382 LEU C CD2 1 
ATOM   10158 N N   . TRP C 1 383 ? 16.715  45.496  57.907  1.00 35.32  ? 383 TRP C N   1 
ATOM   10159 C CA  . TRP C 1 383 ? 15.893  44.427  57.381  1.00 35.65  ? 383 TRP C CA  1 
ATOM   10160 C C   . TRP C 1 383 ? 14.504  44.458  58.012  1.00 39.03  ? 383 TRP C C   1 
ATOM   10161 O O   . TRP C 1 383 ? 13.502  44.306  57.318  1.00 44.86  ? 383 TRP C O   1 
ATOM   10162 C CB  . TRP C 1 383 ? 16.593  43.080  57.625  1.00 38.40  ? 383 TRP C CB  1 
ATOM   10163 C CG  . TRP C 1 383 ? 15.847  41.933  57.003  1.00 36.19  ? 383 TRP C CG  1 
ATOM   10164 C CD1 . TRP C 1 383 ? 14.856  41.230  57.598  1.00 36.78  ? 383 TRP C CD1 1 
ATOM   10165 C CD2 . TRP C 1 383 ? 15.978  41.400  55.673  1.00 36.42  ? 383 TRP C CD2 1 
ATOM   10166 N NE1 . TRP C 1 383 ? 14.349  40.307  56.733  1.00 43.59  ? 383 TRP C NE1 1 
ATOM   10167 C CE2 . TRP C 1 383 ? 15.019  40.377  55.546  1.00 40.99  ? 383 TRP C CE2 1 
ATOM   10168 C CE3 . TRP C 1 383 ? 16.803  41.675  54.584  1.00 40.69  ? 383 TRP C CE3 1 
ATOM   10169 C CZ2 . TRP C 1 383 ? 14.859  39.626  54.385  1.00 42.32  ? 383 TRP C CZ2 1 
ATOM   10170 C CZ3 . TRP C 1 383 ? 16.645  40.940  53.428  1.00 43.42  ? 383 TRP C CZ3 1 
ATOM   10171 C CH2 . TRP C 1 383 ? 15.681  39.935  53.327  1.00 45.27  ? 383 TRP C CH2 1 
ATOM   10172 N N   . HIS C 1 384 ? 14.448  44.645  59.335  1.00 39.71  ? 384 HIS C N   1 
ATOM   10173 C CA  . HIS C 1 384 ? 13.184  44.708  60.044  1.00 37.80  ? 384 HIS C CA  1 
ATOM   10174 C C   . HIS C 1 384 ? 12.255  45.762  59.434  1.00 36.83  ? 384 HIS C C   1 
ATOM   10175 O O   . HIS C 1 384 ? 11.058  45.545  59.338  1.00 34.60  ? 384 HIS C O   1 
ATOM   10176 C CB  . HIS C 1 384 ? 13.420  44.988  61.529  1.00 41.47  ? 384 HIS C CB  1 
ATOM   10177 C CG  . HIS C 1 384 ? 12.165  45.236  62.307  1.00 43.69  ? 384 HIS C CG  1 
ATOM   10178 N ND1 . HIS C 1 384 ? 11.378  44.220  62.806  1.00 43.65  ? 384 HIS C ND1 1 
ATOM   10179 C CD2 . HIS C 1 384 ? 11.570  46.387  62.655  1.00 41.05  ? 384 HIS C CD2 1 
ATOM   10180 C CE1 . HIS C 1 384 ? 10.351  44.755  63.445  1.00 47.53  ? 384 HIS C CE1 1 
ATOM   10181 N NE2 . HIS C 1 384 ? 10.454  46.068  63.373  1.00 44.23  ? 384 HIS C NE2 1 
ATOM   10182 N N   . TYR C 1 385 ? 12.791  46.922  59.056  1.00 35.39  ? 385 TYR C N   1 
ATOM   10183 C CA  . TYR C 1 385 ? 11.946  47.991  58.559  1.00 33.95  ? 385 TYR C CA  1 
ATOM   10184 C C   . TYR C 1 385 ? 11.862  47.958  57.037  1.00 31.01  ? 385 TYR C C   1 
ATOM   10185 O O   . TYR C 1 385 ? 11.375  48.915  56.462  1.00 30.80  ? 385 TYR C O   1 
ATOM   10186 C CB  . TYR C 1 385 ? 12.433  49.359  59.043  1.00 35.96  ? 385 TYR C CB  1 
ATOM   10187 C CG  . TYR C 1 385 ? 12.380  49.531  60.553  1.00 34.45  ? 385 TYR C CG  1 
ATOM   10188 C CD1 . TYR C 1 385 ? 11.171  49.703  61.211  1.00 34.66  ? 385 TYR C CD1 1 
ATOM   10189 C CD2 . TYR C 1 385 ? 13.533  49.518  61.318  1.00 35.84  ? 385 TYR C CD2 1 
ATOM   10190 C CE1 . TYR C 1 385 ? 11.106  49.857  62.585  1.00 30.86  ? 385 TYR C CE1 1 
ATOM   10191 C CE2 . TYR C 1 385 ? 13.486  49.679  62.695  1.00 36.73  ? 385 TYR C CE2 1 
ATOM   10192 C CZ  . TYR C 1 385 ? 12.267  49.851  63.326  1.00 32.69  ? 385 TYR C CZ  1 
ATOM   10193 O OH  . TYR C 1 385 ? 12.229  50.014  64.678  1.00 33.05  ? 385 TYR C OH  1 
ATOM   10194 N N   . GLY C 1 386 ? 12.276  46.858  56.392  1.00 31.14  ? 386 GLY C N   1 
ATOM   10195 C CA  . GLY C 1 386 ? 11.978  46.640  54.972  1.00 31.90  ? 386 GLY C CA  1 
ATOM   10196 C C   . GLY C 1 386 ? 13.035  47.199  53.997  1.00 32.98  ? 386 GLY C C   1 
ATOM   10197 O O   . GLY C 1 386 ? 12.814  47.184  52.797  1.00 26.96  ? 386 GLY C O   1 
ATOM   10198 N N   . ILE C 1 387 ? 14.178  47.712  54.509  1.00 35.78  ? 387 ILE C N   1 
ATOM   10199 C CA  . ILE C 1 387 ? 15.365  47.955  53.705  1.00 30.57  ? 387 ILE C CA  1 
ATOM   10200 C C   . ILE C 1 387 ? 16.155  46.655  53.642  1.00 28.57  ? 387 ILE C C   1 
ATOM   10201 O O   . ILE C 1 387 ? 16.935  46.396  54.531  1.00 27.82  ? 387 ILE C O   1 
ATOM   10202 C CB  . ILE C 1 387 ? 16.210  49.109  54.265  1.00 32.09  ? 387 ILE C CB  1 
ATOM   10203 C CG1 . ILE C 1 387 ? 15.402  50.398  54.433  1.00 32.92  ? 387 ILE C CG1 1 
ATOM   10204 C CG2 . ILE C 1 387 ? 17.443  49.347  53.398  1.00 35.85  ? 387 ILE C CG2 1 
ATOM   10205 C CD1 . ILE C 1 387 ? 15.021  50.723  55.869  1.00 31.35  ? 387 ILE C CD1 1 
ATOM   10206 N N   . ARG C 1 388 ? 16.004  45.917  52.532  1.00 34.11  ? 388 ARG C N   1 
ATOM   10207 C CA  . ARG C 1 388 ? 16.415  44.529  52.386  1.00 38.80  ? 388 ARG C CA  1 
ATOM   10208 C C   . ARG C 1 388 ? 17.424  44.325  51.265  1.00 37.24  ? 388 ARG C C   1 
ATOM   10209 O O   . ARG C 1 388 ? 17.668  43.184  50.866  1.00 35.49  ? 388 ARG C O   1 
ATOM   10210 C CB  . ARG C 1 388 ? 15.244  43.666  51.914  1.00 42.55  ? 388 ARG C CB  1 
ATOM   10211 C CG  . ARG C 1 388 ? 14.064  43.811  52.852  1.00 51.27  ? 388 ARG C CG  1 
ATOM   10212 C CD  . ARG C 1 388 ? 13.172  42.597  52.945  1.00 57.95  ? 388 ARG C CD  1 
ATOM   10213 N NE  . ARG C 1 388 ? 12.632  42.701  54.309  1.00 70.96  ? 388 ARG C NE  1 
ATOM   10214 C CZ  . ARG C 1 388 ? 11.829  41.841  54.917  1.00 68.80  ? 388 ARG C CZ  1 
ATOM   10215 N NH1 . ARG C 1 388 ? 11.386  40.767  54.283  1.00 69.62  ? 388 ARG C NH1 1 
ATOM   10216 N NH2 . ARG C 1 388 ? 11.483  42.069  56.168  1.00 63.38  ? 388 ARG C NH2 1 
ATOM   10217 N N   . GLU C 1 389 ? 17.944  45.434  50.729  1.00 40.04  ? 389 GLU C N   1 
ATOM   10218 C CA  . GLU C 1 389 ? 18.766  45.409  49.526  1.00 35.26  ? 389 GLU C CA  1 
ATOM   10219 C C   . GLU C 1 389 ? 20.232  45.484  49.927  1.00 32.24  ? 389 GLU C C   1 
ATOM   10220 O O   . GLU C 1 389 ? 20.801  46.570  49.969  1.00 29.31  ? 389 GLU C O   1 
ATOM   10221 C CB  . GLU C 1 389 ? 18.370  46.559  48.607  1.00 34.51  ? 389 GLU C CB  1 
ATOM   10222 C CG  . GLU C 1 389 ? 16.986  46.331  48.017  1.00 34.62  ? 389 GLU C CG  1 
ATOM   10223 C CD  . GLU C 1 389 ? 15.814  46.843  48.828  1.00 36.09  ? 389 GLU C CD  1 
ATOM   10224 O OE1 . GLU C 1 389 ? 14.729  46.501  48.344  1.00 39.33  ? 389 GLU C OE1 1 
ATOM   10225 O OE2 . GLU C 1 389 ? 15.925  47.573  49.844  1.00 36.07  ? 389 GLU C OE2 1 
ATOM   10226 N N   . TYR C 1 390 ? 20.786  44.301  50.229  1.00 32.08  ? 390 TYR C N   1 
ATOM   10227 C CA  . TYR C 1 390 ? 22.106  44.122  50.814  1.00 31.52  ? 390 TYR C CA  1 
ATOM   10228 C C   . TYR C 1 390 ? 23.144  45.018  50.144  1.00 31.71  ? 390 TYR C C   1 
ATOM   10229 O O   . TYR C 1 390 ? 23.914  45.673  50.840  1.00 29.30  ? 390 TYR C O   1 
ATOM   10230 C CB  . TYR C 1 390 ? 22.564  42.665  50.683  1.00 33.54  ? 390 TYR C CB  1 
ATOM   10231 C CG  . TYR C 1 390 ? 21.608  41.583  51.190  1.00 38.36  ? 390 TYR C CG  1 
ATOM   10232 C CD1 . TYR C 1 390 ? 21.591  41.225  52.527  1.00 35.49  ? 390 TYR C CD1 1 
ATOM   10233 C CD2 . TYR C 1 390 ? 20.745  40.889  50.333  1.00 41.93  ? 390 TYR C CD2 1 
ATOM   10234 C CE1 . TYR C 1 390 ? 20.758  40.223  52.996  1.00 39.16  ? 390 TYR C CE1 1 
ATOM   10235 C CE2 . TYR C 1 390 ? 19.916  39.867  50.787  1.00 39.09  ? 390 TYR C CE2 1 
ATOM   10236 C CZ  . TYR C 1 390 ? 19.933  39.528  52.130  1.00 39.36  ? 390 TYR C CZ  1 
ATOM   10237 O OH  . TYR C 1 390 ? 19.146  38.543  52.652  1.00 36.28  ? 390 TYR C OH  1 
ATOM   10238 N N   . ASP C 1 391 ? 23.177  45.049  48.801  1.00 33.23  ? 391 ASP C N   1 
ATOM   10239 C CA  . ASP C 1 391 ? 24.284  45.692  48.109  1.00 32.83  ? 391 ASP C CA  1 
ATOM   10240 C C   . ASP C 1 391 ? 24.282  47.155  48.519  1.00 29.77  ? 391 ASP C C   1 
ATOM   10241 O O   . ASP C 1 391 ? 25.344  47.752  48.669  1.00 30.83  ? 391 ASP C O   1 
ATOM   10242 C CB  . ASP C 1 391 ? 24.250  45.479  46.596  1.00 35.38  ? 391 ASP C CB  1 
ATOM   10243 C CG  . ASP C 1 391 ? 24.612  44.080  46.107  1.00 35.24  ? 391 ASP C CG  1 
ATOM   10244 O OD1 . ASP C 1 391 ? 25.170  43.298  46.912  1.00 36.91  ? 391 ASP C OD1 1 
ATOM   10245 O OD2 . ASP C 1 391 ? 24.316  43.768  44.933  1.00 37.13  ? 391 ASP C OD2 1 
ATOM   10246 N N   . PHE C 1 392 ? 23.078  47.691  48.748  1.00 28.12  ? 392 PHE C N   1 
ATOM   10247 C CA  . PHE C 1 392 ? 22.877  49.114  48.996  1.00 27.78  ? 392 PHE C CA  1 
ATOM   10248 C C   . PHE C 1 392 ? 23.357  49.482  50.406  1.00 27.11  ? 392 PHE C C   1 
ATOM   10249 O O   . PHE C 1 392 ? 23.623  50.647  50.724  1.00 25.20  ? 392 PHE C O   1 
ATOM   10250 C CB  . PHE C 1 392 ? 21.383  49.381  48.731  1.00 28.02  ? 392 PHE C CB  1 
ATOM   10251 C CG  . PHE C 1 392 ? 21.083  50.865  48.773  1.00 26.68  ? 392 PHE C CG  1 
ATOM   10252 C CD1 . PHE C 1 392 ? 21.325  51.664  47.672  1.00 26.13  ? 392 PHE C CD1 1 
ATOM   10253 C CD2 . PHE C 1 392 ? 20.630  51.464  49.932  1.00 26.89  ? 392 PHE C CD2 1 
ATOM   10254 C CE1 . PHE C 1 392 ? 21.097  53.022  47.718  1.00 24.90  ? 392 PHE C CE1 1 
ATOM   10255 C CE2 . PHE C 1 392 ? 20.435  52.835  49.982  1.00 28.64  ? 392 PHE C CE2 1 
ATOM   10256 C CZ  . PHE C 1 392 ? 20.654  53.605  48.866  1.00 26.95  ? 392 PHE C CZ  1 
ATOM   10257 N N   . TYR C 1 393 ? 23.477  48.478  51.279  1.00 29.28  ? 393 TYR C N   1 
ATOM   10258 C CA  . TYR C 1 393 ? 23.882  48.726  52.658  1.00 29.95  ? 393 TYR C CA  1 
ATOM   10259 C C   . TYR C 1 393 ? 25.178  49.542  52.649  1.00 32.69  ? 393 TYR C C   1 
ATOM   10260 O O   . TYR C 1 393 ? 25.301  50.500  53.422  1.00 38.78  ? 393 TYR C O   1 
ATOM   10261 C CB  . TYR C 1 393 ? 23.983  47.451  53.508  1.00 26.76  ? 393 TYR C CB  1 
ATOM   10262 C CG  . TYR C 1 393 ? 22.693  46.751  53.906  1.00 30.08  ? 393 TYR C CG  1 
ATOM   10263 C CD1 . TYR C 1 393 ? 21.461  47.088  53.353  1.00 31.24  ? 393 TYR C CD1 1 
ATOM   10264 C CD2 . TYR C 1 393 ? 22.707  45.718  54.826  1.00 31.74  ? 393 TYR C CD2 1 
ATOM   10265 C CE1 . TYR C 1 393 ? 20.293  46.433  53.703  1.00 29.95  ? 393 TYR C CE1 1 
ATOM   10266 C CE2 . TYR C 1 393 ? 21.542  45.068  55.200  1.00 33.57  ? 393 TYR C CE2 1 
ATOM   10267 C CZ  . TYR C 1 393 ? 20.332  45.418  54.631  1.00 32.70  ? 393 TYR C CZ  1 
ATOM   10268 O OH  . TYR C 1 393 ? 19.183  44.758  54.984  1.00 35.81  ? 393 TYR C OH  1 
ATOM   10269 N N   . THR C 1 394 ? 26.129  49.204  51.758  1.00 29.95  ? 394 THR C N   1 
ATOM   10270 C CA  . THR C 1 394 ? 27.408  49.906  51.740  1.00 28.21  ? 394 THR C CA  1 
ATOM   10271 C C   . THR C 1 394 ? 27.214  51.366  51.327  1.00 27.94  ? 394 THR C C   1 
ATOM   10272 O O   . THR C 1 394 ? 28.036  52.210  51.666  1.00 27.86  ? 394 THR C O   1 
ATOM   10273 C CB  . THR C 1 394 ? 28.398  49.197  50.819  1.00 27.02  ? 394 THR C CB  1 
ATOM   10274 O OG1 . THR C 1 394 ? 28.327  47.812  51.133  1.00 25.10  ? 394 THR C OG1 1 
ATOM   10275 C CG2 . THR C 1 394 ? 29.804  49.741  50.990  1.00 27.31  ? 394 THR C CG2 1 
ATOM   10276 N N   . VAL C 1 395 ? 26.139  51.677  50.584  1.00 28.61  ? 395 VAL C N   1 
ATOM   10277 C CA  . VAL C 1 395 ? 25.869  53.062  50.223  1.00 29.79  ? 395 VAL C CA  1 
ATOM   10278 C C   . VAL C 1 395 ? 25.454  53.837  51.480  1.00 29.33  ? 395 VAL C C   1 
ATOM   10279 O O   . VAL C 1 395 ? 25.880  54.974  51.690  1.00 29.75  ? 395 VAL C O   1 
ATOM   10280 C CB  . VAL C 1 395 ? 24.832  53.221  49.092  1.00 27.57  ? 395 VAL C CB  1 
ATOM   10281 C CG1 . VAL C 1 395 ? 24.606  54.690  48.729  1.00 29.30  ? 395 VAL C CG1 1 
ATOM   10282 C CG2 . VAL C 1 395 ? 25.208  52.419  47.859  1.00 26.23  ? 395 VAL C CG2 1 
ATOM   10283 N N   . LEU C 1 396 ? 24.604  53.226  52.313  1.00 31.29  ? 396 LEU C N   1 
ATOM   10284 C CA  . LEU C 1 396 ? 24.142  53.861  53.547  1.00 31.14  ? 396 LEU C CA  1 
ATOM   10285 C C   . LEU C 1 396 ? 25.338  54.215  54.429  1.00 26.37  ? 396 LEU C C   1 
ATOM   10286 O O   . LEU C 1 396 ? 25.452  55.340  54.947  1.00 23.78  ? 396 LEU C O   1 
ATOM   10287 C CB  . LEU C 1 396 ? 23.166  52.906  54.240  1.00 31.21  ? 396 LEU C CB  1 
ATOM   10288 C CG  . LEU C 1 396 ? 21.823  52.696  53.536  1.00 31.74  ? 396 LEU C CG  1 
ATOM   10289 C CD1 . LEU C 1 396 ? 20.991  51.734  54.335  1.00 32.39  ? 396 LEU C CD1 1 
ATOM   10290 C CD2 . LEU C 1 396 ? 21.087  54.007  53.355  1.00 31.94  ? 396 LEU C CD2 1 
ATOM   10291 N N   . PHE C 1 397 ? 26.246  53.236  54.515  1.00 24.17  ? 397 PHE C N   1 
ATOM   10292 C CA  . PHE C 1 397 ? 27.496  53.365  55.247  1.00 26.89  ? 397 PHE C CA  1 
ATOM   10293 C C   . PHE C 1 397 ? 28.270  54.575  54.727  1.00 24.74  ? 397 PHE C C   1 
ATOM   10294 O O   . PHE C 1 397 ? 28.674  55.480  55.484  1.00 22.47  ? 397 PHE C O   1 
ATOM   10295 C CB  . PHE C 1 397 ? 28.226  52.019  55.136  1.00 28.05  ? 397 PHE C CB  1 
ATOM   10296 C CG  . PHE C 1 397 ? 29.445  51.857  56.038  1.00 31.26  ? 397 PHE C CG  1 
ATOM   10297 C CD1 . PHE C 1 397 ? 29.742  52.777  57.038  1.00 31.67  ? 397 PHE C CD1 1 
ATOM   10298 C CD2 . PHE C 1 397 ? 30.289  50.757  55.888  1.00 35.78  ? 397 PHE C CD2 1 
ATOM   10299 C CE1 . PHE C 1 397 ? 30.861  52.627  57.844  1.00 34.23  ? 397 PHE C CE1 1 
ATOM   10300 C CE2 . PHE C 1 397 ? 31.411  50.614  56.695  1.00 36.39  ? 397 PHE C CE2 1 
ATOM   10301 C CZ  . PHE C 1 397 ? 31.699  51.556  57.666  1.00 34.70  ? 397 PHE C CZ  1 
ATOM   10302 N N   . GLY C 1 398 ? 28.398  54.606  53.408  1.00 22.30  ? 398 GLY C N   1 
ATOM   10303 C CA  . GLY C 1 398 ? 29.128  55.668  52.764  1.00 23.64  ? 398 GLY C CA  1 
ATOM   10304 C C   . GLY C 1 398 ? 28.512  57.025  53.060  1.00 24.93  ? 398 GLY C C   1 
ATOM   10305 O O   . GLY C 1 398 ? 29.261  58.016  53.184  1.00 25.62  ? 398 GLY C O   1 
ATOM   10306 N N   . VAL C 1 399 ? 27.166  57.073  53.114  1.00 25.54  ? 399 VAL C N   1 
ATOM   10307 C CA  . VAL C 1 399 ? 26.465  58.340  53.346  1.00 26.79  ? 399 VAL C CA  1 
ATOM   10308 C C   . VAL C 1 399 ? 26.856  58.860  54.732  1.00 27.10  ? 399 VAL C C   1 
ATOM   10309 O O   . VAL C 1 399 ? 27.161  60.035  54.920  1.00 27.52  ? 399 VAL C O   1 
ATOM   10310 C CB  . VAL C 1 399 ? 24.929  58.272  53.193  1.00 26.29  ? 399 VAL C CB  1 
ATOM   10311 C CG1 . VAL C 1 399 ? 24.248  59.539  53.715  1.00 23.72  ? 399 VAL C CG1 1 
ATOM   10312 C CG2 . VAL C 1 399 ? 24.514  58.024  51.743  1.00 27.20  ? 399 VAL C CG2 1 
ATOM   10313 N N   . SER C 1 400 ? 26.870  57.956  55.710  1.00 29.65  ? 400 SER C N   1 
ATOM   10314 C CA  . SER C 1 400 ? 27.233  58.330  57.070  1.00 31.14  ? 400 SER C CA  1 
ATOM   10315 C C   . SER C 1 400 ? 28.694  58.796  57.171  1.00 29.56  ? 400 SER C C   1 
ATOM   10316 O O   . SER C 1 400 ? 29.004  59.814  57.794  1.00 27.03  ? 400 SER C O   1 
ATOM   10317 C CB  . SER C 1 400 ? 26.984  57.174  57.988  1.00 29.00  ? 400 SER C CB  1 
ATOM   10318 O OG  . SER C 1 400 ? 27.544  57.488  59.246  1.00 30.38  ? 400 SER C OG  1 
ATOM   10319 N N   . ARG C 1 401 ? 29.594  58.020  56.553  1.00 28.59  ? 401 ARG C N   1 
ATOM   10320 C CA  . ARG C 1 401 ? 31.022  58.186  56.754  1.00 28.08  ? 401 ARG C CA  1 
ATOM   10321 C C   . ARG C 1 401 ? 31.491  59.466  56.066  1.00 24.59  ? 401 ARG C C   1 
ATOM   10322 O O   . ARG C 1 401 ? 32.534  59.989  56.411  1.00 21.45  ? 401 ARG C O   1 
ATOM   10323 C CB  . ARG C 1 401 ? 31.674  56.852  56.363  1.00 31.00  ? 401 ARG C CB  1 
ATOM   10324 C CG  . ARG C 1 401 ? 33.155  56.719  56.643  1.00 37.43  ? 401 ARG C CG  1 
ATOM   10325 C CD  . ARG C 1 401 ? 33.498  56.929  58.125  1.00 39.43  ? 401 ARG C CD  1 
ATOM   10326 N NE  . ARG C 1 401 ? 33.053  55.815  58.965  1.00 37.13  ? 401 ARG C NE  1 
ATOM   10327 C CZ  . ARG C 1 401 ? 33.703  54.670  59.168  1.00 37.44  ? 401 ARG C CZ  1 
ATOM   10328 N NH1 . ARG C 1 401 ? 34.754  54.323  58.444  1.00 45.89  ? 401 ARG C NH1 1 
ATOM   10329 N NH2 . ARG C 1 401 ? 33.286  53.858  60.110  1.00 37.92  ? 401 ARG C NH2 1 
ATOM   10330 N N   . ALA C 1 402 ? 30.672  60.020  55.162  1.00 24.87  ? 402 ALA C N   1 
ATOM   10331 C CA  . ALA C 1 402 ? 30.938  61.334  54.594  1.00 25.01  ? 402 ALA C CA  1 
ATOM   10332 C C   . ALA C 1 402 ? 30.993  62.419  55.667  1.00 26.08  ? 402 ALA C C   1 
ATOM   10333 O O   . ALA C 1 402 ? 31.557  63.490  55.454  1.00 25.14  ? 402 ALA C O   1 
ATOM   10334 C CB  . ALA C 1 402 ? 29.880  61.686  53.582  1.00 26.17  ? 402 ALA C CB  1 
ATOM   10335 N N   . LEU C 1 403 ? 30.349  62.183  56.812  1.00 29.93  ? 403 LEU C N   1 
ATOM   10336 C CA  . LEU C 1 403 ? 30.373  63.161  57.892  1.00 28.25  ? 403 LEU C CA  1 
ATOM   10337 C C   . LEU C 1 403 ? 31.815  63.243  58.387  1.00 27.82  ? 403 LEU C C   1 
ATOM   10338 O O   . LEU C 1 403 ? 32.434  64.320  58.438  1.00 26.22  ? 403 LEU C O   1 
ATOM   10339 C CB  . LEU C 1 403 ? 29.366  62.728  58.965  1.00 26.79  ? 403 LEU C CB  1 
ATOM   10340 C CG  . LEU C 1 403 ? 27.882  62.735  58.547  1.00 25.50  ? 403 LEU C CG  1 
ATOM   10341 C CD1 . LEU C 1 403 ? 26.991  62.021  59.523  1.00 24.23  ? 403 LEU C CD1 1 
ATOM   10342 C CD2 . LEU C 1 403 ? 27.345  64.146  58.347  1.00 25.61  ? 403 LEU C CD2 1 
ATOM   10343 N N   . GLY C 1 404 ? 32.361  62.058  58.672  1.00 24.42  ? 404 GLY C N   1 
ATOM   10344 C CA  . GLY C 1 404 ? 33.730  61.955  59.125  1.00 25.52  ? 404 GLY C CA  1 
ATOM   10345 C C   . GLY C 1 404 ? 34.708  62.499  58.098  1.00 25.04  ? 404 GLY C C   1 
ATOM   10346 O O   . GLY C 1 404 ? 35.460  63.410  58.419  1.00 25.46  ? 404 GLY C O   1 
ATOM   10347 N N   . CYS C 1 405 ? 34.645  61.958  56.864  1.00 26.69  ? 405 CYS C N   1 
ATOM   10348 C CA  . CYS C 1 405 ? 35.540  62.325  55.774  1.00 23.91  ? 405 CYS C CA  1 
ATOM   10349 C C   . CYS C 1 405 ? 35.537  63.832  55.479  1.00 24.76  ? 405 CYS C C   1 
ATOM   10350 O O   . CYS C 1 405 ? 36.603  64.441  55.358  1.00 26.69  ? 405 CYS C O   1 
ATOM   10351 C CB  . CYS C 1 405 ? 35.223  61.525  54.528  1.00 23.83  ? 405 CYS C CB  1 
ATOM   10352 S SG  . CYS C 1 405 ? 35.476  59.741  54.717  1.00 27.75  ? 405 CYS C SG  1 
ATOM   10353 N N   . THR C 1 406 ? 34.366  64.466  55.363  1.00 24.46  ? 406 THR C N   1 
ATOM   10354 C CA  . THR C 1 406 ? 34.343  65.896  55.094  1.00 24.06  ? 406 THR C CA  1 
ATOM   10355 C C   . THR C 1 406 ? 34.934  66.674  56.266  1.00 25.51  ? 406 THR C C   1 
ATOM   10356 O O   . THR C 1 406 ? 35.705  67.612  56.068  1.00 25.32  ? 406 THR C O   1 
ATOM   10357 C CB  . THR C 1 406 ? 32.924  66.371  54.780  1.00 26.45  ? 406 THR C CB  1 
ATOM   10358 O OG1 . THR C 1 406 ? 32.011  65.940  55.789  1.00 26.53  ? 406 THR C OG1 1 
ATOM   10359 C CG2 . THR C 1 406 ? 32.450  65.910  53.410  1.00 25.56  ? 406 THR C CG2 1 
ATOM   10360 N N   . ALA C 1 407 ? 34.545  66.319  57.499  1.00 28.96  ? 407 ALA C N   1 
ATOM   10361 C CA  . ALA C 1 407 ? 35.079  67.016  58.662  1.00 30.19  ? 407 ALA C CA  1 
ATOM   10362 C C   . ALA C 1 407 ? 36.595  66.927  58.667  1.00 25.81  ? 407 ALA C C   1 
ATOM   10363 O O   . ALA C 1 407 ? 37.266  67.932  58.877  1.00 26.86  ? 407 ALA C O   1 
ATOM   10364 C CB  . ALA C 1 407 ? 34.530  66.454  59.956  1.00 33.75  ? 407 ALA C CB  1 
ATOM   10365 N N   . GLN C 1 408 ? 37.114  65.715  58.440  1.00 24.31  ? 408 GLN C N   1 
ATOM   10366 C CA  . GLN C 1 408 ? 38.553  65.463  58.465  1.00 25.59  ? 408 GLN C CA  1 
ATOM   10367 C C   . GLN C 1 408 ? 39.243  66.335  57.425  1.00 27.75  ? 408 GLN C C   1 
ATOM   10368 O O   . GLN C 1 408 ? 40.209  67.029  57.746  1.00 25.64  ? 408 GLN C O   1 
ATOM   10369 C CB  . GLN C 1 408 ? 38.904  63.989  58.243  1.00 25.89  ? 408 GLN C CB  1 
ATOM   10370 C CG  . GLN C 1 408 ? 38.631  63.109  59.460  1.00 24.76  ? 408 GLN C CG  1 
ATOM   10371 C CD  . GLN C 1 408 ? 39.169  61.699  59.367  1.00 25.47  ? 408 GLN C CD  1 
ATOM   10372 O OE1 . GLN C 1 408 ? 38.524  60.718  59.765  1.00 28.76  ? 408 GLN C OE1 1 
ATOM   10373 N NE2 . GLN C 1 408 ? 40.424  61.587  58.973  1.00 25.91  ? 408 GLN C NE2 1 
ATOM   10374 N N   . ALA C 1 409 ? 38.706  66.314  56.191  1.00 28.18  ? 409 ALA C N   1 
ATOM   10375 C CA  . ALA C 1 409 ? 39.330  66.994  55.070  1.00 26.91  ? 409 ALA C CA  1 
ATOM   10376 C C   . ALA C 1 409 ? 39.319  68.505  55.271  1.00 27.75  ? 409 ALA C C   1 
ATOM   10377 O O   . ALA C 1 409 ? 40.335  69.149  55.001  1.00 28.15  ? 409 ALA C O   1 
ATOM   10378 C CB  . ALA C 1 409 ? 38.664  66.593  53.784  1.00 28.18  ? 409 ALA C CB  1 
ATOM   10379 N N   . ILE C 1 410 ? 38.203  69.067  55.777  1.00 26.75  ? 410 ILE C N   1 
ATOM   10380 C CA  . ILE C 1 410 ? 38.160  70.492  56.102  1.00 24.79  ? 410 ILE C CA  1 
ATOM   10381 C C   . ILE C 1 410 ? 39.304  70.838  57.068  1.00 25.45  ? 410 ILE C C   1 
ATOM   10382 O O   . ILE C 1 410 ? 39.976  71.852  56.910  1.00 26.47  ? 410 ILE C O   1 
ATOM   10383 C CB  . ILE C 1 410 ? 36.782  70.873  56.667  1.00 25.18  ? 410 ILE C CB  1 
ATOM   10384 C CG1 . ILE C 1 410 ? 35.680  70.610  55.664  1.00 26.32  ? 410 ILE C CG1 1 
ATOM   10385 C CG2 . ILE C 1 410 ? 36.728  72.324  57.157  1.00 24.17  ? 410 ILE C CG2 1 
ATOM   10386 C CD1 . ILE C 1 410 ? 34.281  70.644  56.253  1.00 27.15  ? 410 ILE C CD1 1 
ATOM   10387 N N   . LEU C 1 411 ? 39.569  69.965  58.047  1.00 26.14  ? 411 LEU C N   1 
ATOM   10388 C CA  . LEU C 1 411 ? 40.488  70.269  59.145  1.00 28.11  ? 411 LEU C CA  1 
ATOM   10389 C C   . LEU C 1 411 ? 41.954  70.233  58.704  1.00 27.20  ? 411 LEU C C   1 
ATOM   10390 O O   . LEU C 1 411 ? 42.709  71.175  58.991  1.00 24.83  ? 411 LEU C O   1 
ATOM   10391 C CB  . LEU C 1 411 ? 40.257  69.295  60.312  1.00 29.22  ? 411 LEU C CB  1 
ATOM   10392 C CG  . LEU C 1 411 ? 38.954  69.459  61.109  1.00 27.25  ? 411 LEU C CG  1 
ATOM   10393 C CD1 . LEU C 1 411 ? 38.675  68.192  61.893  1.00 27.09  ? 411 LEU C CD1 1 
ATOM   10394 C CD2 . LEU C 1 411 ? 38.997  70.689  62.011  1.00 25.37  ? 411 LEU C CD2 1 
ATOM   10395 N N   . VAL C 1 412 ? 42.343  69.134  58.026  1.00 28.59  ? 412 VAL C N   1 
ATOM   10396 C CA  . VAL C 1 412 ? 43.719  68.921  57.597  1.00 27.52  ? 412 VAL C CA  1 
ATOM   10397 C C   . VAL C 1 412 ? 44.081  70.015  56.601  1.00 28.50  ? 412 VAL C C   1 
ATOM   10398 O O   . VAL C 1 412 ? 45.210  70.498  56.633  1.00 29.98  ? 412 VAL C O   1 
ATOM   10399 C CB  . VAL C 1 412 ? 44.077  67.525  57.039  1.00 30.85  ? 412 VAL C CB  1 
ATOM   10400 C CG1 . VAL C 1 412 ? 43.689  66.403  57.997  1.00 33.47  ? 412 VAL C CG1 1 
ATOM   10401 C CG2 . VAL C 1 412 ? 43.493  67.235  55.668  1.00 30.39  ? 412 VAL C CG2 1 
ATOM   10402 N N   . ARG C 1 413 ? 43.128  70.428  55.751  1.00 31.69  ? 413 ARG C N   1 
ATOM   10403 C CA  . ARG C 1 413 ? 43.330  71.596  54.894  1.00 33.63  ? 413 ARG C CA  1 
ATOM   10404 C C   . ARG C 1 413 ? 43.379  72.899  55.699  1.00 30.90  ? 413 ARG C C   1 
ATOM   10405 O O   . ARG C 1 413 ? 44.025  73.857  55.292  1.00 27.38  ? 413 ARG C O   1 
ATOM   10406 C CB  . ARG C 1 413 ? 42.266  71.722  53.797  1.00 35.80  ? 413 ARG C CB  1 
ATOM   10407 C CG  . ARG C 1 413 ? 42.216  70.559  52.817  1.00 37.21  ? 413 ARG C CG  1 
ATOM   10408 C CD  . ARG C 1 413 ? 43.058  70.822  51.589  1.00 38.40  ? 413 ARG C CD  1 
ATOM   10409 N NE  . ARG C 1 413 ? 44.427  71.216  51.925  1.00 37.68  ? 413 ARG C NE  1 
ATOM   10410 C CZ  . ARG C 1 413 ? 45.325  70.426  52.493  1.00 35.77  ? 413 ARG C CZ  1 
ATOM   10411 N NH1 . ARG C 1 413 ? 45.098  69.115  52.589  1.00 34.92  ? 413 ARG C NH1 1 
ATOM   10412 N NH2 . ARG C 1 413 ? 46.433  70.985  52.961  1.00 32.57  ? 413 ARG C NH2 1 
ATOM   10413 N N   . GLY C 1 414 ? 42.655  72.967  56.814  1.00 32.19  ? 414 GLY C N   1 
ATOM   10414 C CA  . GLY C 1 414 ? 42.764  74.124  57.696  1.00 34.85  ? 414 GLY C CA  1 
ATOM   10415 C C   . GLY C 1 414 ? 44.134  74.192  58.383  1.00 35.27  ? 414 GLY C C   1 
ATOM   10416 O O   . GLY C 1 414 ? 44.700  75.293  58.542  1.00 32.50  ? 414 GLY C O   1 
ATOM   10417 N N   . TYR C 1 415 ? 44.635  73.000  58.776  1.00 31.68  ? 415 TYR C N   1 
ATOM   10418 C CA  . TYR C 1 415 ? 45.940  72.838  59.408  1.00 31.78  ? 415 TYR C CA  1 
ATOM   10419 C C   . TYR C 1 415 ? 47.077  73.093  58.417  1.00 30.14  ? 415 TYR C C   1 
ATOM   10420 O O   . TYR C 1 415 ? 48.180  73.430  58.830  1.00 27.68  ? 415 TYR C O   1 
ATOM   10421 C CB  . TYR C 1 415 ? 46.202  71.437  59.980  1.00 30.87  ? 415 TYR C CB  1 
ATOM   10422 C CG  . TYR C 1 415 ? 45.288  70.836  61.049  1.00 29.00  ? 415 TYR C CG  1 
ATOM   10423 C CD1 . TYR C 1 415 ? 44.363  71.574  61.795  1.00 31.24  ? 415 TYR C CD1 1 
ATOM   10424 C CD2 . TYR C 1 415 ? 45.386  69.475  61.328  1.00 30.38  ? 415 TYR C CD2 1 
ATOM   10425 C CE1 . TYR C 1 415 ? 43.542  70.973  62.749  1.00 29.33  ? 415 TYR C CE1 1 
ATOM   10426 C CE2 . TYR C 1 415 ? 44.591  68.861  62.286  1.00 30.36  ? 415 TYR C CE2 1 
ATOM   10427 C CZ  . TYR C 1 415 ? 43.675  69.611  63.004  1.00 32.20  ? 415 TYR C CZ  1 
ATOM   10428 O OH  . TYR C 1 415 ? 42.967  68.896  63.926  1.00 35.10  ? 415 TYR C OH  1 
ATOM   10429 N N   . MET C 1 416 ? 46.789  72.848  57.127  1.00 35.54  ? 416 MET C N   1 
ATOM   10430 C CA  . MET C 1 416 ? 47.689  72.984  55.988  1.00 31.05  ? 416 MET C CA  1 
ATOM   10431 C C   . MET C 1 416 ? 48.708  71.843  55.951  1.00 31.91  ? 416 MET C C   1 
ATOM   10432 O O   . MET C 1 416 ? 49.839  72.056  55.535  1.00 29.60  ? 416 MET C O   1 
ATOM   10433 C CB  . MET C 1 416 ? 48.390  74.343  55.975  1.00 32.58  ? 416 MET C CB  1 
ATOM   10434 C CG  . MET C 1 416 ? 47.412  75.491  55.992  1.00 36.11  ? 416 MET C CG  1 
ATOM   10435 S SD  . MET C 1 416 ? 48.252  77.077  55.843  1.00 42.13  ? 416 MET C SD  1 
ATOM   10436 C CE  . MET C 1 416 ? 46.883  78.238  55.906  1.00 43.77  ? 416 MET C CE  1 
ATOM   10437 N N   . LEU C 1 417 ? 48.298  70.621  56.328  1.00 31.06  ? 417 LEU C N   1 
ATOM   10438 C CA  . LEU C 1 417 ? 49.146  69.447  56.203  1.00 30.48  ? 417 LEU C CA  1 
ATOM   10439 C C   . LEU C 1 417 ? 49.573  69.281  54.745  1.00 34.15  ? 417 LEU C C   1 
ATOM   10440 O O   . LEU C 1 417 ? 48.783  69.506  53.833  1.00 29.65  ? 417 LEU C O   1 
ATOM   10441 C CB  . LEU C 1 417 ? 48.420  68.179  56.652  1.00 32.23  ? 417 LEU C CB  1 
ATOM   10442 C CG  . LEU C 1 417 ? 47.925  68.123  58.102  1.00 34.55  ? 417 LEU C CG  1 
ATOM   10443 C CD1 . LEU C 1 417 ? 47.570  66.679  58.438  1.00 37.84  ? 417 LEU C CD1 1 
ATOM   10444 C CD2 . LEU C 1 417 ? 48.919  68.706  59.113  1.00 32.74  ? 417 LEU C CD2 1 
ATOM   10445 N N   . PRO C 1 418 ? 50.822  68.834  54.483  1.00 35.04  ? 418 PRO C N   1 
ATOM   10446 C CA  . PRO C 1 418 ? 51.349  68.725  53.125  1.00 32.50  ? 418 PRO C CA  1 
ATOM   10447 C C   . PRO C 1 418 ? 50.923  67.425  52.452  1.00 32.52  ? 418 PRO C C   1 
ATOM   10448 O O   . PRO C 1 418 ? 50.186  66.622  53.040  1.00 31.39  ? 418 PRO C O   1 
ATOM   10449 C CB  . PRO C 1 418 ? 52.864  68.775  53.378  1.00 34.38  ? 418 PRO C CB  1 
ATOM   10450 C CG  . PRO C 1 418 ? 53.010  67.970  54.640  1.00 37.71  ? 418 PRO C CG  1 
ATOM   10451 C CD  . PRO C 1 418 ? 51.800  68.395  55.483  1.00 36.38  ? 418 PRO C CD  1 
ATOM   10452 N N   . ILE C 1 419 ? 51.421  67.250  51.220  1.00 29.09  ? 419 ILE C N   1 
ATOM   10453 C CA  . ILE C 1 419 ? 51.062  66.132  50.374  1.00 29.03  ? 419 ILE C CA  1 
ATOM   10454 C C   . ILE C 1 419 ? 51.507  64.801  50.994  1.00 28.85  ? 419 ILE C C   1 
ATOM   10455 O O   . ILE C 1 419 ? 52.549  64.709  51.642  1.00 28.41  ? 419 ILE C O   1 
ATOM   10456 C CB  . ILE C 1 419 ? 51.630  66.387  48.972  1.00 29.75  ? 419 ILE C CB  1 
ATOM   10457 C CG1 . ILE C 1 419 ? 51.176  65.292  47.994  1.00 32.17  ? 419 ILE C CG1 1 
ATOM   10458 C CG2 . ILE C 1 419 ? 53.158  66.580  49.003  1.00 29.32  ? 419 ILE C CG2 1 
ATOM   10459 C CD1 . ILE C 1 419 ? 51.258  65.691  46.518  1.00 33.06  ? 419 ILE C CD1 1 
ATOM   10460 N N   . GLU C 1 420 ? 50.681  63.767  50.826  1.00 28.80  ? 420 GLU C N   1 
ATOM   10461 C CA  . GLU C 1 420 ? 50.986  62.449  51.360  1.00 31.76  ? 420 GLU C CA  1 
ATOM   10462 C C   . GLU C 1 420 ? 51.874  61.736  50.342  1.00 35.17  ? 420 GLU C C   1 
ATOM   10463 O O   . GLU C 1 420 ? 51.424  61.433  49.233  1.00 33.32  ? 420 GLU C O   1 
ATOM   10464 C CB  . GLU C 1 420 ? 49.715  61.677  51.761  1.00 31.12  ? 420 GLU C CB  1 
ATOM   10465 C CG  . GLU C 1 420 ? 49.959  60.239  52.239  1.00 29.52  ? 420 GLU C CG  1 
ATOM   10466 C CD  . GLU C 1 420 ? 48.758  59.470  52.779  1.00 29.31  ? 420 GLU C CD  1 
ATOM   10467 O OE1 . GLU C 1 420 ? 48.779  58.201  52.879  1.00 26.70  ? 420 GLU C OE1 1 
ATOM   10468 O OE2 . GLU C 1 420 ? 47.782  60.171  53.137  1.00 32.81  ? 420 GLU C OE2 1 
ATOM   10469 N N   . ARG C 1 421 ? 53.117  61.450  50.767  1.00 36.21  ? 421 ARG C N   1 
ATOM   10470 C CA  . ARG C 1 421 ? 54.204  61.030  49.893  1.00 35.80  ? 421 ARG C CA  1 
ATOM   10471 C C   . ARG C 1 421 ? 55.122  60.103  50.688  1.00 32.26  ? 421 ARG C C   1 
ATOM   10472 O O   . ARG C 1 421 ? 56.266  60.437  50.957  1.00 36.04  ? 421 ARG C O   1 
ATOM   10473 C CB  . ARG C 1 421 ? 54.995  62.224  49.311  1.00 33.25  ? 421 ARG C CB  1 
ATOM   10474 N N   . PRO C 1 422 ? 54.691  58.891  51.077  1.00 29.57  ? 422 PRO C N   1 
ATOM   10475 C CA  . PRO C 1 422 ? 55.609  57.929  51.672  1.00 29.73  ? 422 PRO C CA  1 
ATOM   10476 C C   . PRO C 1 422 ? 56.652  57.544  50.641  1.00 30.70  ? 422 PRO C C   1 
ATOM   10477 O O   . PRO C 1 422 ? 56.591  57.991  49.507  1.00 30.71  ? 422 PRO C O   1 
ATOM   10478 C CB  . PRO C 1 422 ? 54.737  56.736  52.044  1.00 29.74  ? 422 PRO C CB  1 
ATOM   10479 C CG  . PRO C 1 422 ? 53.577  56.836  51.071  1.00 29.28  ? 422 PRO C CG  1 
ATOM   10480 C CD  . PRO C 1 422 ? 53.340  58.344  50.905  1.00 30.94  ? 422 PRO C CD  1 
ATOM   10481 N N   . LYS C 1 423 ? 57.566  56.671  51.063  1.00 32.24  ? 423 LYS C N   1 
ATOM   10482 C CA  . LYS C 1 423 ? 58.620  56.140  50.222  1.00 31.93  ? 423 LYS C CA  1 
ATOM   10483 C C   . LYS C 1 423 ? 58.380  54.645  50.049  1.00 28.10  ? 423 LYS C C   1 
ATOM   10484 O O   . LYS C 1 423 ? 58.271  53.909  51.024  1.00 26.89  ? 423 LYS C O   1 
ATOM   10485 C CB  . LYS C 1 423 ? 59.963  56.381  50.924  1.00 36.03  ? 423 LYS C CB  1 
ATOM   10486 C CG  . LYS C 1 423 ? 61.191  55.756  50.296  1.00 38.98  ? 423 LYS C CG  1 
ATOM   10487 C CD  . LYS C 1 423 ? 61.559  56.379  48.948  1.00 43.16  ? 423 LYS C CD  1 
ATOM   10488 C CE  . LYS C 1 423 ? 62.653  55.622  48.248  1.00 43.11  ? 423 LYS C CE  1 
ATOM   10489 N NZ  . LYS C 1 423 ? 62.982  56.377  47.039  1.00 47.39  ? 423 LYS C NZ  1 
ATOM   10490 N N   . SER C 1 424 ? 58.331  54.190  48.808  1.00 24.97  ? 424 SER C N   1 
ATOM   10491 C CA  . SER C 1 424 ? 58.260  52.766  48.580  1.00 27.80  ? 424 SER C CA  1 
ATOM   10492 C C   . SER C 1 424 ? 59.677  52.224  48.468  1.00 28.80  ? 424 SER C C   1 
ATOM   10493 O O   . SER C 1 424 ? 60.597  52.969  48.096  1.00 27.25  ? 424 SER C O   1 
ATOM   10494 C CB  . SER C 1 424 ? 57.448  52.438  47.342  1.00 30.77  ? 424 SER C CB  1 
ATOM   10495 O OG  . SER C 1 424 ? 58.172  52.678  46.140  1.00 33.68  ? 424 SER C OG  1 
ATOM   10496 N N   . ILE C 1 425 ? 59.778  50.908  48.715  1.00 27.92  ? 425 ILE C N   1 
ATOM   10497 C CA  . ILE C 1 425 ? 61.010  50.143  48.689  1.00 28.28  ? 425 ILE C CA  1 
ATOM   10498 C C   . ILE C 1 425 ? 60.808  48.888  47.852  1.00 28.79  ? 425 ILE C C   1 
ATOM   10499 O O   . ILE C 1 425 ? 59.726  48.317  47.805  1.00 30.81  ? 425 ILE C O   1 
ATOM   10500 C CB  . ILE C 1 425 ? 61.440  49.735  50.109  1.00 29.43  ? 425 ILE C CB  1 
ATOM   10501 C CG1 . ILE C 1 425 ? 60.561  48.641  50.700  1.00 29.52  ? 425 ILE C CG1 1 
ATOM   10502 C CG2 . ILE C 1 425 ? 61.526  50.941  51.040  1.00 29.31  ? 425 ILE C CG2 1 
ATOM   10503 C CD1 . ILE C 1 425 ? 60.959  48.280  52.129  1.00 31.68  ? 425 ILE C CD1 1 
ATOM   10504 N N   . THR C 1 426 ? 61.899  48.407  47.275  1.00 32.78  ? 426 THR C N   1 
ATOM   10505 C CA  . THR C 1 426 ? 61.870  47.242  46.413  1.00 34.27  ? 426 THR C CA  1 
ATOM   10506 C C   . THR C 1 426 ? 62.360  46.045  47.225  1.00 33.93  ? 426 THR C C   1 
ATOM   10507 O O   . THR C 1 426 ? 63.103  46.177  48.197  1.00 29.46  ? 426 THR C O   1 
ATOM   10508 C CB  . THR C 1 426 ? 62.719  47.526  45.167  1.00 34.64  ? 426 THR C CB  1 
ATOM   10509 O OG1 . THR C 1 426 ? 64.083  47.664  45.559  1.00 37.91  ? 426 THR C OG1 1 
ATOM   10510 C CG2 . THR C 1 426 ? 62.405  48.860  44.505  1.00 34.26  ? 426 THR C CG2 1 
ATOM   10511 N N   . THR C 1 427 ? 61.905  44.865  46.820  1.00 37.60  ? 427 THR C N   1 
ATOM   10512 C CA  . THR C 1 427 ? 62.415  43.618  47.356  1.00 39.97  ? 427 THR C CA  1 
ATOM   10513 C C   . THR C 1 427 ? 63.913  43.493  47.060  1.00 42.72  ? 427 THR C C   1 
ATOM   10514 O O   . THR C 1 427 ? 64.665  42.960  47.862  1.00 48.16  ? 427 THR C O   1 
ATOM   10515 C CB  . THR C 1 427 ? 61.583  42.501  46.736  1.00 41.85  ? 427 THR C CB  1 
ATOM   10516 O OG1 . THR C 1 427 ? 60.235  42.923  46.956  1.00 35.35  ? 427 THR C OG1 1 
ATOM   10517 C CG2 . THR C 1 427 ? 61.943  41.134  47.301  1.00 42.53  ? 427 THR C CG2 1 
ATOM   10518 N N   . ARG C 1 428 ? 64.353  44.011  45.912  1.00 44.58  ? 428 ARG C N   1 
ATOM   10519 C CA  . ARG C 1 428 ? 65.757  44.014  45.561  1.00 42.90  ? 428 ARG C CA  1 
ATOM   10520 C C   . ARG C 1 428 ? 66.565  44.582  46.729  1.00 39.49  ? 428 ARG C C   1 
ATOM   10521 O O   . ARG C 1 428 ? 67.583  44.031  47.152  1.00 33.20  ? 428 ARG C O   1 
ATOM   10522 C CB  . ARG C 1 428 ? 65.937  44.891  44.313  1.00 48.72  ? 428 ARG C CB  1 
ATOM   10523 C CG  . ARG C 1 428 ? 67.374  44.978  43.815  1.00 50.40  ? 428 ARG C CG  1 
ATOM   10524 C CD  . ARG C 1 428 ? 67.962  46.388  43.629  1.00 53.50  ? 428 ARG C CD  1 
ATOM   10525 N NE  . ARG C 1 428 ? 69.410  46.306  43.903  1.00 83.51  ? 428 ARG C NE  1 
ATOM   10526 C CZ  . ARG C 1 428 ? 70.314  45.460  43.323  1.00 106.30 ? 428 ARG C CZ  1 
ATOM   10527 N NH1 . ARG C 1 428 ? 69.990  44.662  42.311  1.00 105.22 ? 428 ARG C NH1 1 
ATOM   10528 N NH2 . ARG C 1 428 ? 71.573  45.418  43.738  1.00 109.73 ? 428 ARG C NH2 1 
ATOM   10529 N N   . TRP C 1 429 ? 66.128  45.748  47.194  1.00 37.94  ? 429 TRP C N   1 
ATOM   10530 C CA  . TRP C 1 429 ? 66.818  46.481  48.242  1.00 40.36  ? 429 TRP C CA  1 
ATOM   10531 C C   . TRP C 1 429 ? 66.670  45.773  49.583  1.00 39.03  ? 429 TRP C C   1 
ATOM   10532 O O   . TRP C 1 429 ? 67.611  45.703  50.352  1.00 39.42  ? 429 TRP C O   1 
ATOM   10533 C CB  . TRP C 1 429 ? 66.258  47.903  48.326  1.00 38.93  ? 429 TRP C CB  1 
ATOM   10534 C CG  . TRP C 1 429 ? 66.857  48.779  49.387  1.00 40.70  ? 429 TRP C CG  1 
ATOM   10535 C CD1 . TRP C 1 429 ? 67.946  49.594  49.276  1.00 41.26  ? 429 TRP C CD1 1 
ATOM   10536 C CD2 . TRP C 1 429 ? 66.320  48.984  50.710  1.00 44.19  ? 429 TRP C CD2 1 
ATOM   10537 N NE1 . TRP C 1 429 ? 68.133  50.287  50.439  1.00 43.64  ? 429 TRP C NE1 1 
ATOM   10538 C CE2 . TRP C 1 429 ? 67.156  49.934  51.338  1.00 44.10  ? 429 TRP C CE2 1 
ATOM   10539 C CE3 . TRP C 1 429 ? 65.234  48.449  51.415  1.00 41.56  ? 429 TRP C CE3 1 
ATOM   10540 C CZ2 . TRP C 1 429 ? 66.937  50.351  52.647  1.00 42.55  ? 429 TRP C CZ2 1 
ATOM   10541 C CZ3 . TRP C 1 429 ? 65.014  48.877  52.702  1.00 44.26  ? 429 TRP C CZ3 1 
ATOM   10542 C CH2 . TRP C 1 429 ? 65.852  49.818  53.303  1.00 44.61  ? 429 TRP C CH2 1 
ATOM   10543 N N   . VAL C 1 430 ? 65.485  45.243  49.860  1.00 40.13  ? 430 VAL C N   1 
ATOM   10544 C CA  . VAL C 1 430 ? 65.301  44.497  51.088  1.00 42.53  ? 430 VAL C CA  1 
ATOM   10545 C C   . VAL C 1 430 ? 66.369  43.400  51.137  1.00 40.57  ? 430 VAL C C   1 
ATOM   10546 O O   . VAL C 1 430 ? 67.103  43.332  52.111  1.00 36.17  ? 430 VAL C O   1 
ATOM   10547 C CB  . VAL C 1 430 ? 63.843  43.997  51.182  1.00 45.32  ? 430 VAL C CB  1 
ATOM   10548 C CG1 . VAL C 1 430 ? 63.613  43.053  52.358  1.00 44.97  ? 430 VAL C CG1 1 
ATOM   10549 C CG2 . VAL C 1 430 ? 62.867  45.173  51.254  1.00 44.08  ? 430 VAL C CG2 1 
ATOM   10550 N N   . LYS C 1 431 ? 66.509  42.621  50.054  1.00 41.92  ? 431 LYS C N   1 
ATOM   10551 C CA  . LYS C 1 431 ? 67.407  41.476  49.985  1.00 44.26  ? 431 LYS C CA  1 
ATOM   10552 C C   . LYS C 1 431 ? 68.870  41.897  50.088  1.00 43.04  ? 431 LYS C C   1 
ATOM   10553 O O   . LYS C 1 431 ? 69.690  41.173  50.636  1.00 47.10  ? 431 LYS C O   1 
ATOM   10554 C CB  . LYS C 1 431 ? 67.272  40.714  48.662  1.00 49.26  ? 431 LYS C CB  1 
ATOM   10555 C CG  . LYS C 1 431 ? 65.954  39.982  48.446  1.00 54.64  ? 431 LYS C CG  1 
ATOM   10556 C CD  . LYS C 1 431 ? 65.899  39.187  47.145  1.00 62.44  ? 431 LYS C CD  1 
ATOM   10557 C CE  . LYS C 1 431 ? 66.727  37.921  47.189  1.00 68.44  ? 431 LYS C CE  1 
ATOM   10558 N NZ  . LYS C 1 431 ? 67.032  37.354  45.870  1.00 66.47  ? 431 LYS C NZ  1 
ATOM   10559 N N   . GLU C 1 432 ? 69.209  43.059  49.549  1.00 42.44  ? 432 GLU C N   1 
ATOM   10560 C CA  . GLU C 1 432 ? 70.559  43.596  49.673  1.00 43.77  ? 432 GLU C CA  1 
ATOM   10561 C C   . GLU C 1 432 ? 70.922  43.856  51.146  1.00 44.86  ? 432 GLU C C   1 
ATOM   10562 O O   . GLU C 1 432 ? 72.021  43.518  51.570  1.00 47.07  ? 432 GLU C O   1 
ATOM   10563 C CB  . GLU C 1 432 ? 70.657  44.842  48.779  1.00 40.56  ? 432 GLU C CB  1 
ATOM   10564 C CG  . GLU C 1 432 ? 72.032  45.494  48.662  1.00 40.71  ? 432 GLU C CG  1 
ATOM   10565 C CD  . GLU C 1 432 ? 72.082  46.936  48.150  1.00 44.12  ? 432 GLU C CD  1 
ATOM   10566 O OE1 . GLU C 1 432 ? 73.083  47.604  48.472  1.00 46.73  ? 432 GLU C OE1 1 
ATOM   10567 O OE2 . GLU C 1 432 ? 71.180  47.418  47.433  1.00 51.52  ? 432 GLU C OE2 1 
ATOM   10568 N N   . VAL C 1 433 ? 69.996  44.417  51.933  1.00 43.03  ? 433 VAL C N   1 
ATOM   10569 C CA  . VAL C 1 433 ? 70.321  45.233  53.099  1.00 42.47  ? 433 VAL C CA  1 
ATOM   10570 C C   . VAL C 1 433 ? 69.890  44.578  54.418  1.00 43.46  ? 433 VAL C C   1 
ATOM   10571 O O   . VAL C 1 433 ? 70.401  44.925  55.482  1.00 41.97  ? 433 VAL C O   1 
ATOM   10572 C CB  . VAL C 1 433 ? 69.601  46.580  52.867  1.00 49.03  ? 433 VAL C CB  1 
ATOM   10573 C CG1 . VAL C 1 433 ? 69.077  47.204  54.154  1.00 54.09  ? 433 VAL C CG1 1 
ATOM   10574 C CG2 . VAL C 1 433 ? 70.440  47.577  52.064  1.00 47.43  ? 433 VAL C CG2 1 
ATOM   10575 N N   . ALA C 1 434 ? 68.959  43.622  54.335  1.00 45.35  ? 434 ALA C N   1 
ATOM   10576 C CA  . ALA C 1 434 ? 68.214  43.105  55.471  1.00 51.38  ? 434 ALA C CA  1 
ATOM   10577 C C   . ALA C 1 434 ? 69.122  42.553  56.565  1.00 59.97  ? 434 ALA C C   1 
ATOM   10578 O O   . ALA C 1 434 ? 68.854  42.755  57.747  1.00 61.70  ? 434 ALA C O   1 
ATOM   10579 C CB  . ALA C 1 434 ? 67.274  42.024  55.003  1.00 52.35  ? 434 ALA C CB  1 
ATOM   10580 N N   . GLU C 1 435 ? 70.149  41.801  56.156  1.00 71.97  ? 435 GLU C N   1 
ATOM   10581 C CA  . GLU C 1 435 ? 71.135  41.247  57.072  1.00 63.84  ? 435 GLU C CA  1 
ATOM   10582 C C   . GLU C 1 435 ? 71.842  42.372  57.817  1.00 54.14  ? 435 GLU C C   1 
ATOM   10583 O O   . GLU C 1 435 ? 71.980  42.311  59.026  1.00 69.11  ? 435 GLU C O   1 
ATOM   10584 C CB  . GLU C 1 435 ? 72.160  40.371  56.348  1.00 63.41  ? 435 GLU C CB  1 
ATOM   10585 C CG  . GLU C 1 435 ? 71.585  39.035  55.880  1.00 67.05  ? 435 GLU C CG  1 
ATOM   10586 C CD  . GLU C 1 435 ? 71.314  38.028  56.986  1.00 66.11  ? 435 GLU C CD  1 
ATOM   10587 O OE1 . GLU C 1 435 ? 71.320  38.421  58.169  1.00 73.94  ? 435 GLU C OE1 1 
ATOM   10588 O OE2 . GLU C 1 435 ? 71.143  36.834  56.673  1.00 61.95  ? 435 GLU C OE2 1 
ATOM   10589 N N   . SER C 1 436 ? 72.232  43.425  57.109  1.00 51.87  ? 436 SER C N   1 
ATOM   10590 C CA  . SER C 1 436 ? 73.011  44.484  57.724  1.00 52.42  ? 436 SER C CA  1 
ATOM   10591 C C   . SER C 1 436 ? 72.176  45.288  58.711  1.00 54.51  ? 436 SER C C   1 
ATOM   10592 O O   . SER C 1 436 ? 72.720  46.153  59.390  1.00 63.96  ? 436 SER C O   1 
ATOM   10593 C CB  . SER C 1 436 ? 73.602  45.419  56.684  1.00 53.43  ? 436 SER C CB  1 
ATOM   10594 O OG  . SER C 1 436 ? 72.769  46.551  56.460  1.00 48.94  ? 436 SER C OG  1 
ATOM   10595 N N   . LEU C 1 437 ? 70.855  45.063  58.737  1.00 55.74  ? 437 LEU C N   1 
ATOM   10596 C CA  . LEU C 1 437 ? 69.937  45.986  59.396  1.00 47.26  ? 437 LEU C CA  1 
ATOM   10597 C C   . LEU C 1 437 ? 69.766  45.625  60.871  1.00 40.56  ? 437 LEU C C   1 
ATOM   10598 O O   . LEU C 1 437 ? 69.662  44.454  61.247  1.00 38.75  ? 437 LEU C O   1 
ATOM   10599 C CB  . LEU C 1 437 ? 68.598  46.007  58.655  1.00 47.37  ? 437 LEU C CB  1 
ATOM   10600 C CG  . LEU C 1 437 ? 68.174  47.335  58.009  1.00 51.10  ? 437 LEU C CG  1 
ATOM   10601 C CD1 . LEU C 1 437 ? 69.300  48.157  57.449  1.00 54.94  ? 437 LEU C CD1 1 
ATOM   10602 C CD2 . LEU C 1 437 ? 67.150  47.077  56.922  1.00 51.47  ? 437 LEU C CD2 1 
ATOM   10603 N N   . PRO C 1 438 ? 69.669  46.643  61.750  1.00 37.29  ? 438 PRO C N   1 
ATOM   10604 C CA  . PRO C 1 438 ? 69.352  46.416  63.160  1.00 41.89  ? 438 PRO C CA  1 
ATOM   10605 C C   . PRO C 1 438 ? 67.997  45.746  63.367  1.00 42.90  ? 438 PRO C C   1 
ATOM   10606 O O   . PRO C 1 438 ? 67.072  45.956  62.598  1.00 44.81  ? 438 PRO C O   1 
ATOM   10607 C CB  . PRO C 1 438 ? 69.387  47.827  63.796  1.00 40.33  ? 438 PRO C CB  1 
ATOM   10608 C CG  . PRO C 1 438 ? 69.190  48.764  62.630  1.00 42.68  ? 438 PRO C CG  1 
ATOM   10609 C CD  . PRO C 1 438 ? 69.791  48.069  61.423  1.00 39.48  ? 438 PRO C CD  1 
ATOM   10610 N N   . VAL C 1 439 ? 67.882  44.933  64.418  1.00 47.63  ? 439 VAL C N   1 
ATOM   10611 C CA  . VAL C 1 439 ? 66.594  44.410  64.837  1.00 44.60  ? 439 VAL C CA  1 
ATOM   10612 C C   . VAL C 1 439 ? 65.789  45.556  65.453  1.00 43.73  ? 439 VAL C C   1 
ATOM   10613 O O   . VAL C 1 439 ? 66.361  46.573  65.843  1.00 41.91  ? 439 VAL C O   1 
ATOM   10614 C CB  . VAL C 1 439 ? 66.906  43.255  65.800  1.00 51.62  ? 439 VAL C CB  1 
ATOM   10615 C CG1 . VAL C 1 439 ? 65.703  42.870  66.640  1.00 62.97  ? 439 VAL C CG1 1 
ATOM   10616 C CG2 . VAL C 1 439 ? 67.438  42.041  65.046  1.00 50.33  ? 439 VAL C CG2 1 
ATOM   10617 N N   . ALA C 1 440 ? 64.457  45.433  65.487  1.00 46.26  ? 440 ALA C N   1 
ATOM   10618 C CA  . ALA C 1 440 ? 63.608  46.476  66.064  1.00 55.00  ? 440 ALA C CA  1 
ATOM   10619 C C   . ALA C 1 440 ? 63.914  46.666  67.553  1.00 55.09  ? 440 ALA C C   1 
ATOM   10620 O O   . ALA C 1 440 ? 63.894  45.688  68.306  1.00 48.99  ? 440 ALA C O   1 
ATOM   10621 C CB  . ALA C 1 440 ? 62.151  46.133  65.849  1.00 57.51  ? 440 ALA C CB  1 
ATOM   10622 N N   . GLY C 1 441 ? 64.157  47.931  67.950  1.00 59.37  ? 441 GLY C N   1 
ATOM   10623 C CA  . GLY C 1 441 ? 64.990  48.276  69.098  1.00 69.91  ? 441 GLY C CA  1 
ATOM   10624 C C   . GLY C 1 441 ? 66.378  48.789  68.677  1.00 84.71  ? 441 GLY C C   1 
ATOM   10625 O O   . GLY C 1 441 ? 66.493  49.640  67.790  1.00 92.33  ? 441 GLY C O   1 
ATOM   10626 N N   . SER C 1 442 ? 67.430  48.228  69.299  1.00 82.76  ? 442 SER C N   1 
ATOM   10627 C CA  . SER C 1 442 ? 68.793  48.765  69.304  1.00 82.16  ? 442 SER C CA  1 
ATOM   10628 C C   . SER C 1 442 ? 68.931  50.071  68.504  1.00 70.17  ? 442 SER C C   1 
ATOM   10629 O O   . SER C 1 442 ? 69.620  50.971  69.048  1.00 58.46  ? 442 SER C O   1 
ATOM   10630 C CB  . SER C 1 442 ? 69.814  47.731  68.855  1.00 80.18  ? 442 SER C CB  1 
ATOM   10631 O OG  . SER C 1 442 ? 69.331  46.967  67.760  1.00 68.01  ? 442 SER C OG  1 
ATOM   10632 N N   . MET D 1 1   ? 45.045  74.911  -2.012  1.00 53.00  ? 1   MET D N   1 
ATOM   10633 C CA  . MET D 1 1   ? 43.806  75.091  -2.814  1.00 49.15  ? 1   MET D CA  1 
ATOM   10634 C C   . MET D 1 1   ? 43.956  76.333  -3.697  1.00 42.39  ? 1   MET D C   1 
ATOM   10635 O O   . MET D 1 1   ? 44.123  77.445  -3.206  1.00 38.41  ? 1   MET D O   1 
ATOM   10636 C CB  . MET D 1 1   ? 42.570  75.199  -1.908  1.00 46.44  ? 1   MET D CB  1 
ATOM   10637 C CG  . MET D 1 1   ? 41.254  75.157  -2.685  1.00 52.44  ? 1   MET D CG  1 
ATOM   10638 S SD  . MET D 1 1   ? 39.723  74.854  -1.762  1.00 54.56  ? 1   MET D SD  1 
ATOM   10639 C CE  . MET D 1 1   ? 39.618  76.406  -0.862  1.00 55.42  ? 1   MET D CE  1 
ATOM   10640 N N   . LYS D 1 2   ? 43.880  76.124  -5.014  1.00 41.77  ? 2   LYS D N   1 
ATOM   10641 C CA  . LYS D 1 2   ? 43.996  77.193  -5.995  1.00 41.14  ? 2   LYS D CA  1 
ATOM   10642 C C   . LYS D 1 2   ? 42.969  78.287  -5.712  1.00 38.10  ? 2   LYS D C   1 
ATOM   10643 O O   . LYS D 1 2   ? 43.273  79.463  -5.880  1.00 36.73  ? 2   LYS D O   1 
ATOM   10644 C CB  . LYS D 1 2   ? 43.840  76.605  -7.401  1.00 44.77  ? 2   LYS D CB  1 
ATOM   10645 C CG  . LYS D 1 2   ? 43.835  77.574  -8.575  1.00 54.13  ? 2   LYS D CG  1 
ATOM   10646 C CD  . LYS D 1 2   ? 45.212  78.085  -8.984  1.00 60.67  ? 2   LYS D CD  1 
ATOM   10647 C CE  . LYS D 1 2   ? 45.260  78.410  -10.444 1.00 68.01  ? 2   LYS D CE  1 
ATOM   10648 N NZ  . LYS D 1 2   ? 46.634  78.390  -10.954 1.00 73.27  ? 2   LYS D NZ  1 
ATOM   10649 N N   . LEU D 1 3   ? 41.767  77.907  -5.254  1.00 36.94  ? 3   LEU D N   1 
ATOM   10650 C CA  . LEU D 1 3   ? 40.733  78.893  -4.987  1.00 33.30  ? 3   LEU D CA  1 
ATOM   10651 C C   . LEU D 1 3   ? 41.260  79.934  -4.006  1.00 31.91  ? 3   LEU D C   1 
ATOM   10652 O O   . LEU D 1 3   ? 41.074  81.127  -4.218  1.00 26.71  ? 3   LEU D O   1 
ATOM   10653 C CB  . LEU D 1 3   ? 39.442  78.253  -4.474  1.00 34.76  ? 3   LEU D CB  1 
ATOM   10654 C CG  . LEU D 1 3   ? 38.356  79.227  -3.985  1.00 32.19  ? 3   LEU D CG  1 
ATOM   10655 C CD1 . LEU D 1 3   ? 37.805  80.092  -5.084  1.00 30.76  ? 3   LEU D CD1 1 
ATOM   10656 C CD2 . LEU D 1 3   ? 37.254  78.447  -3.308  1.00 31.59  ? 3   LEU D CD2 1 
ATOM   10657 N N   . LYS D 1 4   ? 41.897  79.464  -2.929  1.00 34.57  ? 4   LYS D N   1 
ATOM   10658 C CA  . LYS D 1 4   ? 42.431  80.340  -1.898  1.00 37.47  ? 4   LYS D CA  1 
ATOM   10659 C C   . LYS D 1 4   ? 43.578  81.193  -2.443  1.00 38.93  ? 4   LYS D C   1 
ATOM   10660 O O   . LYS D 1 4   ? 43.600  82.421  -2.253  1.00 39.43  ? 4   LYS D O   1 
ATOM   10661 C CB  . LYS D 1 4   ? 42.895  79.573  -0.650  1.00 39.68  ? 4   LYS D CB  1 
ATOM   10662 C CG  . LYS D 1 4   ? 43.376  80.516  0.424   1.00 40.25  ? 4   LYS D CG  1 
ATOM   10663 C CD  . LYS D 1 4   ? 43.251  80.047  1.863   1.00 47.06  ? 4   LYS D CD  1 
ATOM   10664 C CE  . LYS D 1 4   ? 43.098  81.277  2.740   1.00 49.26  ? 4   LYS D CE  1 
ATOM   10665 N NZ  . LYS D 1 4   ? 43.584  81.164  4.118   1.00 43.98  ? 4   LYS D NZ  1 
ATOM   10666 N N   . GLU D 1 5   ? 44.530  80.549  -3.131  1.00 38.85  ? 5   GLU D N   1 
ATOM   10667 C CA  . GLU D 1 5   ? 45.703  81.258  -3.647  1.00 40.41  ? 5   GLU D CA  1 
ATOM   10668 C C   . GLU D 1 5   ? 45.261  82.416  -4.547  1.00 37.30  ? 5   GLU D C   1 
ATOM   10669 O O   . GLU D 1 5   ? 45.852  83.496  -4.563  1.00 40.42  ? 5   GLU D O   1 
ATOM   10670 C CB  . GLU D 1 5   ? 46.646  80.316  -4.395  1.00 38.38  ? 5   GLU D CB  1 
ATOM   10671 C CG  . GLU D 1 5   ? 47.252  79.220  -3.518  1.00 38.67  ? 5   GLU D CG  1 
ATOM   10672 C CD  . GLU D 1 5   ? 47.931  78.117  -4.312  1.00 44.90  ? 5   GLU D CD  1 
ATOM   10673 O OE1 . GLU D 1 5   ? 48.724  77.400  -3.678  1.00 51.47  ? 5   GLU D OE1 1 
ATOM   10674 O OE2 . GLU D 1 5   ? 47.678  77.958  -5.531  1.00 42.35  ? 5   GLU D OE2 1 
ATOM   10675 N N   . ARG D 1 6   ? 44.168  82.184  -5.257  1.00 30.75  ? 6   ARG D N   1 
ATOM   10676 C CA  . ARG D 1 6   ? 43.618  83.161  -6.172  1.00 32.94  ? 6   ARG D CA  1 
ATOM   10677 C C   . ARG D 1 6   ? 42.950  84.302  -5.400  1.00 35.93  ? 6   ARG D C   1 
ATOM   10678 O O   . ARG D 1 6   ? 43.212  85.478  -5.649  1.00 38.39  ? 6   ARG D O   1 
ATOM   10679 C CB  . ARG D 1 6   ? 42.693  82.273  -7.002  1.00 33.03  ? 6   ARG D CB  1 
ATOM   10680 C CG  . ARG D 1 6   ? 42.759  82.388  -8.504  1.00 35.79  ? 6   ARG D CG  1 
ATOM   10681 C CD  . ARG D 1 6   ? 44.140  82.442  -9.122  1.00 33.69  ? 6   ARG D CD  1 
ATOM   10682 N NE  . ARG D 1 6   ? 43.908  83.615  -9.972  1.00 35.65  ? 6   ARG D NE  1 
ATOM   10683 C CZ  . ARG D 1 6   ? 44.388  84.818  -9.770  1.00 34.43  ? 6   ARG D CZ  1 
ATOM   10684 N NH1 . ARG D 1 6   ? 45.517  84.915  -9.090  1.00 37.80  ? 6   ARG D NH1 1 
ATOM   10685 N NH2 . ARG D 1 6   ? 43.781  85.867  -10.320 1.00 30.68  ? 6   ARG D NH2 1 
ATOM   10686 N N   . LEU D 1 7   ? 42.083  83.959  -4.447  1.00 32.20  ? 7   LEU D N   1 
ATOM   10687 C CA  . LEU D 1 7   ? 41.428  84.974  -3.641  1.00 32.14  ? 7   LEU D CA  1 
ATOM   10688 C C   . LEU D 1 7   ? 42.458  85.815  -2.881  1.00 31.79  ? 7   LEU D C   1 
ATOM   10689 O O   . LEU D 1 7   ? 42.260  87.028  -2.672  1.00 27.99  ? 7   LEU D O   1 
ATOM   10690 C CB  . LEU D 1 7   ? 40.441  84.257  -2.719  1.00 34.07  ? 7   LEU D CB  1 
ATOM   10691 C CG  . LEU D 1 7   ? 39.163  83.706  -3.377  1.00 30.33  ? 7   LEU D CG  1 
ATOM   10692 C CD1 . LEU D 1 7   ? 38.321  83.035  -2.313  1.00 29.86  ? 7   LEU D CD1 1 
ATOM   10693 C CD2 . LEU D 1 7   ? 38.368  84.783  -4.075  1.00 26.41  ? 7   LEU D CD2 1 
ATOM   10694 N N   . ALA D 1 8   ? 43.578  85.171  -2.515  1.00 31.54  ? 8   ALA D N   1 
ATOM   10695 C CA  . ALA D 1 8   ? 44.656  85.867  -1.827  1.00 33.05  ? 8   ALA D CA  1 
ATOM   10696 C C   . ALA D 1 8   ? 45.228  86.992  -2.692  1.00 32.12  ? 8   ALA D C   1 
ATOM   10697 O O   . ALA D 1 8   ? 45.682  87.994  -2.142  1.00 30.41  ? 8   ALA D O   1 
ATOM   10698 C CB  . ALA D 1 8   ? 45.739  84.897  -1.384  1.00 31.60  ? 8   ALA D CB  1 
ATOM   10699 N N   . GLU D 1 9   ? 45.227  86.821  -4.022  1.00 31.78  ? 9   GLU D N   1 
ATOM   10700 C CA  . GLU D 1 9   ? 45.624  87.891  -4.925  1.00 33.59  ? 9   GLU D CA  1 
ATOM   10701 C C   . GLU D 1 9   ? 44.472  88.859  -5.153  1.00 30.63  ? 9   GLU D C   1 
ATOM   10702 O O   . GLU D 1 9   ? 44.658  90.069  -5.074  1.00 32.03  ? 9   GLU D O   1 
ATOM   10703 C CB  . GLU D 1 9   ? 46.057  87.461  -6.324  1.00 38.82  ? 9   GLU D CB  1 
ATOM   10704 C CG  . GLU D 1 9   ? 47.413  86.765  -6.347  1.00 51.03  ? 9   GLU D CG  1 
ATOM   10705 C CD  . GLU D 1 9   ? 48.083  86.689  -7.717  1.00 63.50  ? 9   GLU D CD  1 
ATOM   10706 O OE1 . GLU D 1 9   ? 49.299  86.374  -7.702  1.00 69.52  ? 9   GLU D OE1 1 
ATOM   10707 O OE2 . GLU D 1 9   ? 47.434  86.937  -8.777  1.00 61.91  ? 9   GLU D OE2 1 
ATOM   10708 N N   . LEU D 1 10  ? 43.279  88.331  -5.436  1.00 30.34  ? 10  LEU D N   1 
ATOM   10709 C CA  . LEU D 1 10  ? 42.202  89.150  -5.978  1.00 29.68  ? 10  LEU D CA  1 
ATOM   10710 C C   . LEU D 1 10  ? 41.592  90.084  -4.933  1.00 31.05  ? 10  LEU D C   1 
ATOM   10711 O O   . LEU D 1 10  ? 41.280  91.232  -5.233  1.00 33.51  ? 10  LEU D O   1 
ATOM   10712 C CB  . LEU D 1 10  ? 41.156  88.228  -6.601  1.00 30.71  ? 10  LEU D CB  1 
ATOM   10713 C CG  . LEU D 1 10  ? 41.571  87.530  -7.908  1.00 32.51  ? 10  LEU D CG  1 
ATOM   10714 C CD1 . LEU D 1 10  ? 40.563  86.482  -8.309  1.00 34.05  ? 10  LEU D CD1 1 
ATOM   10715 C CD2 . LEU D 1 10  ? 41.727  88.496  -9.051  1.00 30.18  ? 10  LEU D CD2 1 
ATOM   10716 N N   . ILE D 1 11  ? 41.355  89.581  -3.715  1.00 32.18  ? 11  ILE D N   1 
ATOM   10717 C CA  . ILE D 1 11  ? 40.595  90.339  -2.733  1.00 31.56  ? 11  ILE D CA  1 
ATOM   10718 C C   . ILE D 1 11  ? 41.350  91.609  -2.352  1.00 29.95  ? 11  ILE D C   1 
ATOM   10719 O O   . ILE D 1 11  ? 40.742  92.668  -2.270  1.00 32.54  ? 11  ILE D O   1 
ATOM   10720 C CB  . ILE D 1 11  ? 40.240  89.465  -1.514  1.00 33.24  ? 11  ILE D CB  1 
ATOM   10721 C CG1 . ILE D 1 11  ? 39.087  88.485  -1.871  1.00 34.93  ? 11  ILE D CG1 1 
ATOM   10722 C CG2 . ILE D 1 11  ? 39.910  90.333  -0.294  1.00 28.92  ? 11  ILE D CG2 1 
ATOM   10723 C CD1 . ILE D 1 11  ? 38.753  87.440  -0.819  1.00 34.23  ? 11  ILE D CD1 1 
ATOM   10724 N N   . PRO D 1 12  ? 42.679  91.572  -2.094  1.00 29.59  ? 12  PRO D N   1 
ATOM   10725 C CA  . PRO D 1 12  ? 43.419  92.803  -1.825  1.00 31.24  ? 12  PRO D CA  1 
ATOM   10726 C C   . PRO D 1 12  ? 43.209  93.826  -2.936  1.00 30.10  ? 12  PRO D C   1 
ATOM   10727 O O   . PRO D 1 12  ? 43.012  95.003  -2.671  1.00 30.61  ? 12  PRO D O   1 
ATOM   10728 C CB  . PRO D 1 12  ? 44.897  92.355  -1.678  1.00 33.38  ? 12  PRO D CB  1 
ATOM   10729 C CG  . PRO D 1 12  ? 44.814  90.868  -1.322  1.00 32.18  ? 12  PRO D CG  1 
ATOM   10730 C CD  . PRO D 1 12  ? 43.531  90.375  -1.992  1.00 30.26  ? 12  PRO D CD  1 
ATOM   10731 N N   . GLN D 1 13  ? 43.220  93.360  -4.180  1.00 32.27  ? 13  GLN D N   1 
ATOM   10732 C CA  . GLN D 1 13  ? 42.971  94.227  -5.324  1.00 38.17  ? 13  GLN D CA  1 
ATOM   10733 C C   . GLN D 1 13  ? 41.591  94.874  -5.275  1.00 35.79  ? 13  GLN D C   1 
ATOM   10734 O O   . GLN D 1 13  ? 41.485  96.096  -5.415  1.00 33.91  ? 13  GLN D O   1 
ATOM   10735 C CB  . GLN D 1 13  ? 43.076  93.366  -6.577  1.00 43.05  ? 13  GLN D CB  1 
ATOM   10736 C CG  . GLN D 1 13  ? 42.881  94.115  -7.886  1.00 46.79  ? 13  GLN D CG  1 
ATOM   10737 C CD  . GLN D 1 13  ? 43.095  93.168  -9.044  1.00 53.44  ? 13  GLN D CD  1 
ATOM   10738 O OE1 . GLN D 1 13  ? 43.989  92.296  -9.000  1.00 45.37  ? 13  GLN D OE1 1 
ATOM   10739 N NE2 . GLN D 1 13  ? 42.214  93.296  -10.033 1.00 49.77  ? 13  GLN D NE2 1 
ATOM   10740 N N   . TRP D 1 14  ? 40.561  94.018  -5.112  1.00 33.66  ? 14  TRP D N   1 
ATOM   10741 C CA  . TRP D 1 14  ? 39.157  94.411  -5.088  1.00 28.95  ? 14  TRP D CA  1 
ATOM   10742 C C   . TRP D 1 14  ? 38.865  95.334  -3.912  1.00 27.79  ? 14  TRP D C   1 
ATOM   10743 O O   . TRP D 1 14  ? 38.059  96.245  -4.030  1.00 27.49  ? 14  TRP D O   1 
ATOM   10744 C CB  . TRP D 1 14  ? 38.272  93.166  -4.971  1.00 28.32  ? 14  TRP D CB  1 
ATOM   10745 C CG  . TRP D 1 14  ? 38.226  92.291  -6.187  1.00 28.27  ? 14  TRP D CG  1 
ATOM   10746 C CD1 . TRP D 1 14  ? 38.426  92.678  -7.472  1.00 28.81  ? 14  TRP D CD1 1 
ATOM   10747 C CD2 . TRP D 1 14  ? 37.926  90.875  -6.227  1.00 32.17  ? 14  TRP D CD2 1 
ATOM   10748 N NE1 . TRP D 1 14  ? 38.272  91.609  -8.313  1.00 30.68  ? 14  TRP D NE1 1 
ATOM   10749 C CE2 . TRP D 1 14  ? 37.954  90.491  -7.589  1.00 31.59  ? 14  TRP D CE2 1 
ATOM   10750 C CE3 . TRP D 1 14  ? 37.639  89.899  -5.261  1.00 29.16  ? 14  TRP D CE3 1 
ATOM   10751 C CZ2 . TRP D 1 14  ? 37.699  89.183  -8.008  1.00 30.87  ? 14  TRP D CZ2 1 
ATOM   10752 C CZ3 . TRP D 1 14  ? 37.411  88.605  -5.677  1.00 31.65  ? 14  TRP D CZ3 1 
ATOM   10753 C CH2 . TRP D 1 14  ? 37.405  88.256  -7.035  1.00 30.35  ? 14  TRP D CH2 1 
ATOM   10754 N N   . ARG D 1 15  ? 39.465  95.038  -2.754  1.00 29.25  ? 15  ARG D N   1 
ATOM   10755 C CA  . ARG D 1 15  ? 39.328  95.876  -1.578  1.00 32.32  ? 15  ARG D CA  1 
ATOM   10756 C C   . ARG D 1 15  ? 39.801  97.306  -1.892  1.00 33.89  ? 15  ARG D C   1 
ATOM   10757 O O   . ARG D 1 15  ? 39.163  98.283  -1.483  1.00 32.84  ? 15  ARG D O   1 
ATOM   10758 C CB  . ARG D 1 15  ? 40.072  95.127  -0.465  1.00 36.04  ? 15  ARG D CB  1 
ATOM   10759 C CG  . ARG D 1 15  ? 40.291  95.961  0.783   1.00 42.66  ? 15  ARG D CG  1 
ATOM   10760 C CD  . ARG D 1 15  ? 40.849  95.182  1.952   1.00 45.98  ? 15  ARG D CD  1 
ATOM   10761 N NE  . ARG D 1 15  ? 41.991  94.301  1.675   1.00 52.89  ? 15  ARG D NE  1 
ATOM   10762 C CZ  . ARG D 1 15  ? 42.089  93.009  2.071   1.00 59.24  ? 15  ARG D CZ  1 
ATOM   10763 N NH1 . ARG D 1 15  ? 41.016  92.305  2.496   1.00 50.45  ? 15  ARG D NH1 1 
ATOM   10764 N NH2 . ARG D 1 15  ? 43.281  92.419  2.000   1.00 50.90  ? 15  ARG D NH2 1 
ATOM   10765 N N   . ALA D 1 16  ? 40.915  97.448  -2.631  1.00 33.27  ? 16  ALA D N   1 
ATOM   10766 C CA  . ALA D 1 16  ? 41.468  98.770  -2.928  1.00 35.41  ? 16  ALA D CA  1 
ATOM   10767 C C   . ALA D 1 16  ? 40.578  99.504  -3.925  1.00 34.64  ? 16  ALA D C   1 
ATOM   10768 O O   . ALA D 1 16  ? 40.321  100.686 -3.748  1.00 38.98  ? 16  ALA D O   1 
ATOM   10769 C CB  . ALA D 1 16  ? 42.904  98.697  -3.419  1.00 32.84  ? 16  ALA D CB  1 
ATOM   10770 N N   . GLU D 1 17  ? 40.075  98.775  -4.924  1.00 34.50  ? 17  GLU D N   1 
ATOM   10771 C CA  . GLU D 1 17  ? 39.126  99.282  -5.910  1.00 37.47  ? 17  GLU D CA  1 
ATOM   10772 C C   . GLU D 1 17  ? 37.853  99.809  -5.228  1.00 33.66  ? 17  GLU D C   1 
ATOM   10773 O O   . GLU D 1 17  ? 37.324  100.863 -5.568  1.00 31.74  ? 17  GLU D O   1 
ATOM   10774 C CB  . GLU D 1 17  ? 38.816  98.069  -6.796  1.00 47.68  ? 17  GLU D CB  1 
ATOM   10775 C CG  . GLU D 1 17  ? 38.939  98.240  -8.309  1.00 57.95  ? 17  GLU D CG  1 
ATOM   10776 C CD  . GLU D 1 17  ? 38.750  96.936  -9.092  1.00 58.22  ? 17  GLU D CD  1 
ATOM   10777 O OE1 . GLU D 1 17  ? 37.714  96.854  -9.805  1.00 59.08  ? 17  GLU D OE1 1 
ATOM   10778 O OE2 . GLU D 1 17  ? 39.627  96.021  -9.007  1.00 45.51  ? 17  GLU D OE2 1 
ATOM   10779 N N   . VAL D 1 18  ? 37.320  99.046  -4.272  1.00 33.27  ? 18  VAL D N   1 
ATOM   10780 C CA  . VAL D 1 18  ? 36.125  99.443  -3.537  1.00 33.12  ? 18  VAL D CA  1 
ATOM   10781 C C   . VAL D 1 18  ? 36.422  100.676 -2.683  1.00 31.38  ? 18  VAL D C   1 
ATOM   10782 O O   . VAL D 1 18  ? 35.618  101.595 -2.654  1.00 30.84  ? 18  VAL D O   1 
ATOM   10783 C CB  . VAL D 1 18  ? 35.573  98.274  -2.692  1.00 34.57  ? 18  VAL D CB  1 
ATOM   10784 C CG1 . VAL D 1 18  ? 34.525  98.718  -1.683  1.00 35.60  ? 18  VAL D CG1 1 
ATOM   10785 C CG2 . VAL D 1 18  ? 34.999  97.167  -3.571  1.00 36.93  ? 18  VAL D CG2 1 
ATOM   10786 N N   . ALA D 1 19  ? 37.565  100.694 -1.980  1.00 33.30  ? 19  ALA D N   1 
ATOM   10787 C CA  . ALA D 1 19  ? 37.986  101.892 -1.262  1.00 34.81  ? 19  ALA D CA  1 
ATOM   10788 C C   . ALA D 1 19  ? 37.903  103.117 -2.160  1.00 37.71  ? 19  ALA D C   1 
ATOM   10789 O O   . ALA D 1 19  ? 37.364  104.162 -1.759  1.00 35.20  ? 19  ALA D O   1 
ATOM   10790 C CB  . ALA D 1 19  ? 39.392  101.744 -0.770  1.00 35.84  ? 19  ALA D CB  1 
ATOM   10791 N N   . GLU D 1 20  ? 38.501  102.956 -3.351  1.00 36.33  ? 20  GLU D N   1 
ATOM   10792 C CA  . GLU D 1 20  ? 38.652  104.021 -4.335  1.00 38.62  ? 20  GLU D CA  1 
ATOM   10793 C C   . GLU D 1 20  ? 37.262  104.489 -4.770  1.00 32.91  ? 20  GLU D C   1 
ATOM   10794 O O   . GLU D 1 20  ? 36.998  105.694 -4.849  1.00 26.81  ? 20  GLU D O   1 
ATOM   10795 C CB  . GLU D 1 20  ? 39.556  103.475 -5.449  1.00 46.98  ? 20  GLU D CB  1 
ATOM   10796 C CG  . GLU D 1 20  ? 40.177  104.522 -6.366  1.00 52.18  ? 20  GLU D CG  1 
ATOM   10797 C CD  . GLU D 1 20  ? 40.926  105.581 -5.590  1.00 60.25  ? 20  GLU D CD  1 
ATOM   10798 O OE1 . GLU D 1 20  ? 41.791  105.178 -4.767  1.00 63.74  ? 20  GLU D OE1 1 
ATOM   10799 O OE2 . GLU D 1 20  ? 40.630  106.787 -5.802  1.00 68.43  ? 20  GLU D OE2 1 
ATOM   10800 N N   . ILE D 1 21  ? 36.359  103.525 -4.985  1.00 28.70  ? 21  ILE D N   1 
ATOM   10801 C CA  . ILE D 1 21  ? 35.012  103.855 -5.401  1.00 31.83  ? 21  ILE D CA  1 
ATOM   10802 C C   . ILE D 1 21  ? 34.308  104.689 -4.331  1.00 34.00  ? 21  ILE D C   1 
ATOM   10803 O O   . ILE D 1 21  ? 33.704  105.724 -4.644  1.00 32.43  ? 21  ILE D O   1 
ATOM   10804 C CB  . ILE D 1 21  ? 34.226  102.592 -5.801  1.00 35.22  ? 21  ILE D CB  1 
ATOM   10805 C CG1 . ILE D 1 21  ? 34.665  102.133 -7.172  1.00 36.68  ? 21  ILE D CG1 1 
ATOM   10806 C CG2 . ILE D 1 21  ? 32.719  102.837 -5.761  1.00 38.31  ? 21  ILE D CG2 1 
ATOM   10807 C CD1 . ILE D 1 21  ? 34.165  100.761 -7.557  1.00 39.61  ? 21  ILE D CD1 1 
ATOM   10808 N N   . ARG D 1 22  ? 34.387  104.254 -3.070  1.00 35.82  ? 22  ARG D N   1 
ATOM   10809 C CA  . ARG D 1 22  ? 33.690  104.958 -1.996  1.00 38.20  ? 22  ARG D CA  1 
ATOM   10810 C C   . ARG D 1 22  ? 34.230  106.382 -1.839  1.00 36.44  ? 22  ARG D C   1 
ATOM   10811 O O   . ARG D 1 22  ? 33.456  107.318 -1.677  1.00 39.88  ? 22  ARG D O   1 
ATOM   10812 C CB  . ARG D 1 22  ? 33.708  104.159 -0.685  1.00 38.18  ? 22  ARG D CB  1 
ATOM   10813 C CG  . ARG D 1 22  ? 33.023  102.795 -0.759  1.00 39.26  ? 22  ARG D CG  1 
ATOM   10814 C CD  . ARG D 1 22  ? 33.242  101.980 0.533   1.00 38.76  ? 22  ARG D CD  1 
ATOM   10815 N NE  . ARG D 1 22  ? 32.559  102.607 1.670   1.00 37.34  ? 22  ARG D NE  1 
ATOM   10816 C CZ  . ARG D 1 22  ? 32.795  102.385 2.960   1.00 38.07  ? 22  ARG D CZ  1 
ATOM   10817 N NH1 . ARG D 1 22  ? 33.893  101.785 3.379   1.00 35.33  ? 22  ARG D NH1 1 
ATOM   10818 N NH2 . ARG D 1 22  ? 31.909  102.790 3.842   1.00 39.93  ? 22  ARG D NH2 1 
ATOM   10819 N N   . LYS D 1 23  ? 35.549  106.550 -1.937  1.00 41.87  ? 23  LYS D N   1 
ATOM   10820 C CA  . LYS D 1 23  ? 36.182  107.859 -1.827  1.00 48.24  ? 23  LYS D CA  1 
ATOM   10821 C C   . LYS D 1 23  ? 35.811  108.770 -3.003  1.00 45.46  ? 23  LYS D C   1 
ATOM   10822 O O   . LYS D 1 23  ? 35.436  109.916 -2.803  1.00 42.08  ? 23  LYS D O   1 
ATOM   10823 C CB  . LYS D 1 23  ? 37.703  107.685 -1.678  1.00 55.41  ? 23  LYS D CB  1 
ATOM   10824 C CG  . LYS D 1 23  ? 38.456  109.005 -1.701  1.00 68.44  ? 23  LYS D CG  1 
ATOM   10825 C CD  . LYS D 1 23  ? 39.704  109.126 -0.835  1.00 75.76  ? 23  LYS D CD  1 
ATOM   10826 C CE  . LYS D 1 23  ? 40.181  110.558 -0.854  1.00 81.29  ? 23  LYS D CE  1 
ATOM   10827 N NZ  . LYS D 1 23  ? 41.059  110.851 0.283   1.00 83.17  ? 23  LYS D NZ  1 
ATOM   10828 N N   . LYS D 1 24  ? 35.912  108.267 -4.236  1.00 47.40  ? 24  LYS D N   1 
ATOM   10829 C CA  . LYS D 1 24  ? 35.934  109.129 -5.411  1.00 51.07  ? 24  LYS D CA  1 
ATOM   10830 C C   . LYS D 1 24  ? 34.520  109.329 -5.946  1.00 49.76  ? 24  LYS D C   1 
ATOM   10831 O O   . LYS D 1 24  ? 34.236  110.345 -6.577  1.00 44.79  ? 24  LYS D O   1 
ATOM   10832 C CB  . LYS D 1 24  ? 36.877  108.494 -6.441  1.00 58.97  ? 24  LYS D CB  1 
ATOM   10833 C CG  . LYS D 1 24  ? 37.415  109.336 -7.601  1.00 65.49  ? 24  LYS D CG  1 
ATOM   10834 C CD  . LYS D 1 24  ? 38.460  108.558 -8.410  1.00 69.63  ? 24  LYS D CD  1 
ATOM   10835 C CE  . LYS D 1 24  ? 39.267  109.368 -9.377  1.00 74.03  ? 24  LYS D CE  1 
ATOM   10836 N NZ  . LYS D 1 24  ? 38.484  109.735 -10.558 1.00 74.47  ? 24  LYS D NZ  1 
ATOM   10837 N N   . TYR D 1 25  ? 33.637  108.356 -5.688  1.00 49.59  ? 25  TYR D N   1 
ATOM   10838 C CA  . TYR D 1 25  ? 32.321  108.356 -6.305  1.00 50.02  ? 25  TYR D CA  1 
ATOM   10839 C C   . TYR D 1 25  ? 31.202  108.251 -5.271  1.00 42.63  ? 25  TYR D C   1 
ATOM   10840 O O   . TYR D 1 25  ? 30.048  108.096 -5.653  1.00 45.79  ? 25  TYR D O   1 
ATOM   10841 C CB  . TYR D 1 25  ? 32.253  107.210 -7.324  1.00 55.78  ? 25  TYR D CB  1 
ATOM   10842 C CG  . TYR D 1 25  ? 33.166  107.399 -8.527  1.00 54.99  ? 25  TYR D CG  1 
ATOM   10843 C CD1 . TYR D 1 25  ? 33.099  108.548 -9.306  1.00 54.19  ? 25  TYR D CD1 1 
ATOM   10844 C CD2 . TYR D 1 25  ? 34.122  106.442 -8.856  1.00 59.59  ? 25  TYR D CD2 1 
ATOM   10845 C CE1 . TYR D 1 25  ? 33.951  108.738 -10.382 1.00 60.29  ? 25  TYR D CE1 1 
ATOM   10846 C CE2 . TYR D 1 25  ? 34.982  106.619 -9.930  1.00 61.14  ? 25  TYR D CE2 1 
ATOM   10847 C CZ  . TYR D 1 25  ? 34.896  107.772 -10.693 1.00 64.04  ? 25  TYR D CZ  1 
ATOM   10848 O OH  . TYR D 1 25  ? 35.741  107.945 -11.747 1.00 66.30  ? 25  TYR D OH  1 
ATOM   10849 N N   . GLY D 1 26  ? 31.513  108.365 -3.979  1.00 40.80  ? 26  GLY D N   1 
ATOM   10850 C CA  . GLY D 1 26  ? 30.521  108.095 -2.951  1.00 40.09  ? 26  GLY D CA  1 
ATOM   10851 C C   . GLY D 1 26  ? 29.245  108.930 -3.119  1.00 41.41  ? 26  GLY D C   1 
ATOM   10852 O O   . GLY D 1 26  ? 28.138  108.425 -2.869  1.00 36.01  ? 26  GLY D O   1 
ATOM   10853 N N   . ASN D 1 27  ? 29.415  110.205 -3.536  1.00 40.93  ? 27  ASN D N   1 
ATOM   10854 C CA  . ASN D 1 27  ? 28.311  111.156 -3.669  1.00 47.98  ? 27  ASN D CA  1 
ATOM   10855 C C   . ASN D 1 27  ? 27.689  111.163 -5.074  1.00 43.72  ? 27  ASN D C   1 
ATOM   10856 O O   . ASN D 1 27  ? 26.953  112.088 -5.393  1.00 46.13  ? 27  ASN D O   1 
ATOM   10857 C CB  . ASN D 1 27  ? 28.733  112.577 -3.302  1.00 54.14  ? 27  ASN D CB  1 
ATOM   10858 C CG  . ASN D 1 27  ? 29.934  113.054 -4.098  1.00 61.77  ? 27  ASN D CG  1 
ATOM   10859 O OD1 . ASN D 1 27  ? 30.497  112.309 -4.914  1.00 49.35  ? 27  ASN D OD1 1 
ATOM   10860 N ND2 . ASN D 1 27  ? 30.362  114.288 -3.854  1.00 70.09  ? 27  ASN D ND2 1 
ATOM   10861 N N   . ARG D 1 28  ? 27.952  110.129 -5.889  1.00 42.51  ? 28  ARG D N   1 
ATOM   10862 C CA  . ARG D 1 28  ? 27.366  109.980 -7.214  1.00 42.17  ? 28  ARG D CA  1 
ATOM   10863 C C   . ARG D 1 28  ? 25.985  109.338 -7.123  1.00 42.71  ? 28  ARG D C   1 
ATOM   10864 O O   . ARG D 1 28  ? 25.843  108.208 -6.657  1.00 47.06  ? 28  ARG D O   1 
ATOM   10865 C CB  . ARG D 1 28  ? 28.258  109.090 -8.088  1.00 42.64  ? 28  ARG D CB  1 
ATOM   10866 C CG  . ARG D 1 28  ? 29.580  109.734 -8.485  1.00 44.64  ? 28  ARG D CG  1 
ATOM   10867 C CD  . ARG D 1 28  ? 29.366  110.930 -9.424  1.00 45.83  ? 28  ARG D CD  1 
ATOM   10868 N NE  . ARG D 1 28  ? 30.586  111.734 -9.562  1.00 46.25  ? 28  ARG D NE  1 
ATOM   10869 C CZ  . ARG D 1 28  ? 31.235  112.001 -10.683 1.00 42.11  ? 28  ARG D CZ  1 
ATOM   10870 N NH1 . ARG D 1 28  ? 32.455  112.485 -10.613 1.00 44.65  ? 28  ARG D NH1 1 
ATOM   10871 N NH2 . ARG D 1 28  ? 30.731  111.689 -11.858 1.00 42.20  ? 28  ARG D NH2 1 
ATOM   10872 N N   . LYS D 1 29  ? 24.976  110.058 -7.626  1.00 41.81  ? 29  LYS D N   1 
ATOM   10873 C CA  . LYS D 1 29  ? 23.584  109.664 -7.504  1.00 39.83  ? 29  LYS D CA  1 
ATOM   10874 C C   . LYS D 1 29  ? 23.211  108.599 -8.530  1.00 38.95  ? 29  LYS D C   1 
ATOM   10875 O O   . LYS D 1 29  ? 23.503  108.745 -9.709  1.00 41.97  ? 29  LYS D O   1 
ATOM   10876 C CB  . LYS D 1 29  ? 22.692  110.894 -7.688  1.00 40.54  ? 29  LYS D CB  1 
ATOM   10877 C CG  . LYS D 1 29  ? 21.238  110.611 -8.052  1.00 41.51  ? 29  LYS D CG  1 
ATOM   10878 C CD  . LYS D 1 29  ? 20.374  111.862 -8.153  1.00 44.91  ? 29  LYS D CD  1 
ATOM   10879 C CE  . LYS D 1 29  ? 18.960  111.549 -8.552  1.00 49.99  ? 29  LYS D CE  1 
ATOM   10880 N NZ  . LYS D 1 29  ? 18.036  112.625 -8.184  1.00 53.46  ? 29  LYS D NZ  1 
ATOM   10881 N N   . THR D 1 30  ? 22.484  107.570 -8.074  1.00 40.36  ? 30  THR D N   1 
ATOM   10882 C CA  . THR D 1 30  ? 22.023  106.483 -8.922  1.00 38.06  ? 30  THR D CA  1 
ATOM   10883 C C   . THR D 1 30  ? 20.547  106.640 -9.244  1.00 37.62  ? 30  THR D C   1 
ATOM   10884 O O   . THR D 1 30  ? 20.103  106.216 -10.310 1.00 44.30  ? 30  THR D O   1 
ATOM   10885 C CB  . THR D 1 30  ? 22.271  105.141 -8.229  1.00 38.09  ? 30  THR D CB  1 
ATOM   10886 O OG1 . THR D 1 30  ? 21.553  105.122 -6.992  1.00 37.17  ? 30  THR D OG1 1 
ATOM   10887 C CG2 . THR D 1 30  ? 23.758  104.904 -8.051  1.00 37.86  ? 30  THR D CG2 1 
ATOM   10888 N N   . MET D 1 31  ? 19.779  107.148 -8.279  1.00 36.93  ? 31  MET D N   1 
ATOM   10889 C CA  . MET D 1 31  ? 18.333  107.212 -8.423  1.00 40.66  ? 31  MET D CA  1 
ATOM   10890 C C   . MET D 1 31  ? 17.766  108.049 -7.290  1.00 41.40  ? 31  MET D C   1 
ATOM   10891 O O   . MET D 1 31  ? 18.495  108.430 -6.383  1.00 42.10  ? 31  MET D O   1 
ATOM   10892 C CB  . MET D 1 31  ? 17.661  105.829 -8.423  1.00 39.33  ? 31  MET D CB  1 
ATOM   10893 C CG  . MET D 1 31  ? 18.042  104.910 -7.278  1.00 37.64  ? 31  MET D CG  1 
ATOM   10894 S SD  . MET D 1 31  ? 17.436  103.227 -7.545  1.00 41.11  ? 31  MET D SD  1 
ATOM   10895 C CE  . MET D 1 31  ? 15.685  103.566 -7.759  1.00 39.94  ? 31  MET D CE  1 
ATOM   10896 N N   . ASP D 1 32  ? 16.470  108.356 -7.397  1.00 42.84  ? 32  ASP D N   1 
ATOM   10897 C CA  . ASP D 1 32  ? 15.731  109.018 -6.338  1.00 39.71  ? 32  ASP D CA  1 
ATOM   10898 C C   . ASP D 1 32  ? 15.230  107.937 -5.384  1.00 42.20  ? 32  ASP D C   1 
ATOM   10899 O O   . ASP D 1 32  ? 14.728  106.905 -5.847  1.00 43.45  ? 32  ASP D O   1 
ATOM   10900 C CB  . ASP D 1 32  ? 14.567  109.817 -6.904  1.00 40.53  ? 32  ASP D CB  1 
ATOM   10901 C CG  . ASP D 1 32  ? 14.897  111.105 -7.641  1.00 40.47  ? 32  ASP D CG  1 
ATOM   10902 O OD1 . ASP D 1 32  ? 15.985  111.672 -7.433  1.00 46.39  ? 32  ASP D OD1 1 
ATOM   10903 O OD2 . ASP D 1 32  ? 14.055  111.541 -8.416  1.00 44.88  ? 32  ASP D OD2 1 
ATOM   10904 N N   . CYS D 1 33  ? 15.408  108.182 -4.073  1.00 39.03  ? 33  CYS D N   1 
ATOM   10905 C CA  . CYS D 1 33  ? 14.745  107.430 -3.019  1.00 37.90  ? 33  CYS D CA  1 
ATOM   10906 C C   . CYS D 1 33  ? 13.388  108.076 -2.744  1.00 34.65  ? 33  CYS D C   1 
ATOM   10907 O O   . CYS D 1 33  ? 13.307  109.276 -2.530  1.00 38.77  ? 33  CYS D O   1 
ATOM   10908 C CB  . CYS D 1 33  ? 15.607  107.368 -1.757  1.00 40.74  ? 33  CYS D CB  1 
ATOM   10909 S SG  . CYS D 1 33  ? 15.020  106.197 -0.497  1.00 38.81  ? 33  CYS D SG  1 
ATOM   10910 N N   . THR D 1 34  ? 12.328  107.267 -2.719  1.00 32.70  ? 34  THR D N   1 
ATOM   10911 C CA  . THR D 1 34  ? 10.973  107.770 -2.643  1.00 34.24  ? 34  THR D CA  1 
ATOM   10912 C C   . THR D 1 34  ? 10.252  107.141 -1.467  1.00 40.35  ? 34  THR D C   1 
ATOM   10913 O O   . THR D 1 34  ? 10.693  106.152 -0.866  1.00 41.01  ? 34  THR D O   1 
ATOM   10914 C CB  . THR D 1 34  ? 10.174  107.432 -3.901  1.00 37.77  ? 34  THR D CB  1 
ATOM   10915 O OG1 . THR D 1 34  ? 9.955   106.019 -3.845  1.00 33.74  ? 34  THR D OG1 1 
ATOM   10916 C CG2 . THR D 1 34  ? 10.860  107.904 -5.174  1.00 39.35  ? 34  THR D CG2 1 
ATOM   10917 N N   . ILE D 1 35  ? 9.056   107.682 -1.243  1.00 39.30  ? 35  ILE D N   1 
ATOM   10918 C CA  . ILE D 1 35  ? 8.186   107.188 -0.203  1.00 35.84  ? 35  ILE D CA  1 
ATOM   10919 C C   . ILE D 1 35  ? 7.710   105.794 -0.564  1.00 32.98  ? 35  ILE D C   1 
ATOM   10920 O O   . ILE D 1 35  ? 7.517   104.978 0.326   1.00 34.35  ? 35  ILE D O   1 
ATOM   10921 C CB  . ILE D 1 35  ? 7.086   108.222 0.072   1.00 36.23  ? 35  ILE D CB  1 
ATOM   10922 C CG1 . ILE D 1 35  ? 7.669   109.272 0.994   1.00 39.84  ? 35  ILE D CG1 1 
ATOM   10923 C CG2 . ILE D 1 35  ? 5.820   107.591 0.636   1.00 34.54  ? 35  ILE D CG2 1 
ATOM   10924 C CD1 . ILE D 1 35  ? 6.688   110.348 1.369   1.00 50.71  ? 35  ILE D CD1 1 
ATOM   10925 N N   . GLY D 1 36  ? 7.586   105.521 -1.865  1.00 34.09  ? 36  GLY D N   1 
ATOM   10926 C CA  . GLY D 1 36  ? 7.163   104.207 -2.334  1.00 33.95  ? 36  GLY D CA  1 
ATOM   10927 C C   . GLY D 1 36  ? 8.179   103.117 -2.011  1.00 34.86  ? 36  GLY D C   1 
ATOM   10928 O O   . GLY D 1 36  ? 7.805   101.972 -1.768  1.00 32.81  ? 36  GLY D O   1 
ATOM   10929 N N   . HIS D 1 37  ? 9.467   103.501 -2.018  1.00 35.70  ? 37  HIS D N   1 
ATOM   10930 C CA  . HIS D 1 37  ? 10.562  102.609 -1.677  1.00 35.98  ? 37  HIS D CA  1 
ATOM   10931 C C   . HIS D 1 37  ? 10.440  102.104 -0.231  1.00 35.77  ? 37  HIS D C   1 
ATOM   10932 O O   . HIS D 1 37  ? 10.661  100.916 0.042   1.00 34.72  ? 37  HIS D O   1 
ATOM   10933 C CB  . HIS D 1 37  ? 11.898  103.305 -1.974  1.00 35.87  ? 37  HIS D CB  1 
ATOM   10934 C CG  . HIS D 1 37  ? 12.221  103.410 -3.426  1.00 36.53  ? 37  HIS D CG  1 
ATOM   10935 N ND1 . HIS D 1 37  ? 11.968  102.379 -4.305  1.00 36.37  ? 37  HIS D ND1 1 
ATOM   10936 C CD2 . HIS D 1 37  ? 12.778  104.395 -4.154  1.00 36.03  ? 37  HIS D CD2 1 
ATOM   10937 C CE1 . HIS D 1 37  ? 12.364  102.741 -5.515  1.00 37.75  ? 37  HIS D CE1 1 
ATOM   10938 N NE2 . HIS D 1 37  ? 12.863  103.962 -5.445  1.00 38.26  ? 37  HIS D NE2 1 
ATOM   10939 N N   . ALA D 1 38  ? 10.068  103.011 0.685   1.00 34.18  ? 38  ALA D N   1 
ATOM   10940 C CA  . ALA D 1 38  ? 10.043  102.740 2.116   1.00 32.87  ? 38  ALA D CA  1 
ATOM   10941 C C   . ALA D 1 38  ? 8.855   101.846 2.486   1.00 34.00  ? 38  ALA D C   1 
ATOM   10942 O O   . ALA D 1 38  ? 9.031   100.880 3.223   1.00 34.52  ? 38  ALA D O   1 
ATOM   10943 C CB  . ALA D 1 38  ? 10.030  104.050 2.873   1.00 31.71  ? 38  ALA D CB  1 
ATOM   10944 N N   . TYR D 1 39  ? 7.671   102.140 1.934   1.00 31.83  ? 39  TYR D N   1 
ATOM   10945 C CA  . TYR D 1 39  ? 6.485   101.313 2.117   1.00 31.78  ? 39  TYR D CA  1 
ATOM   10946 C C   . TYR D 1 39  ? 6.392   100.171 1.103   1.00 31.34  ? 39  TYR D C   1 
ATOM   10947 O O   . TYR D 1 39  ? 5.442   99.391  1.176   1.00 28.64  ? 39  TYR D O   1 
ATOM   10948 C CB  . TYR D 1 39  ? 5.198   102.130 1.945   1.00 30.50  ? 39  TYR D CB  1 
ATOM   10949 C CG  . TYR D 1 39  ? 4.954   103.119 3.075   1.00 30.80  ? 39  TYR D CG  1 
ATOM   10950 C CD1 . TYR D 1 39  ? 5.602   104.343 3.112   1.00 33.72  ? 39  TYR D CD1 1 
ATOM   10951 C CD2 . TYR D 1 39  ? 4.120   102.811 4.131   1.00 29.69  ? 39  TYR D CD2 1 
ATOM   10952 C CE1 . TYR D 1 39  ? 5.387   105.244 4.141   1.00 32.83  ? 39  TYR D CE1 1 
ATOM   10953 C CE2 . TYR D 1 39  ? 3.918   103.691 5.175   1.00 31.14  ? 39  TYR D CE2 1 
ATOM   10954 C CZ  . TYR D 1 39  ? 4.542   104.920 5.179   1.00 31.21  ? 39  TYR D CZ  1 
ATOM   10955 O OH  . TYR D 1 39  ? 4.338   105.812 6.201   1.00 32.78  ? 39  TYR D OH  1 
ATOM   10956 N N   . GLY D 1 40  ? 7.338   100.080 0.148   1.00 31.80  ? 40  GLY D N   1 
ATOM   10957 C CA  . GLY D 1 40  ? 7.223   99.097  -0.931  1.00 32.83  ? 40  GLY D CA  1 
ATOM   10958 C C   . GLY D 1 40  ? 8.368   98.075  -0.979  1.00 32.44  ? 40  GLY D C   1 
ATOM   10959 O O   . GLY D 1 40  ? 8.802   97.670  -2.055  1.00 31.85  ? 40  GLY D O   1 
ATOM   10960 N N   . GLY D 1 41  ? 8.867   97.644  0.184   1.00 30.62  ? 41  GLY D N   1 
ATOM   10961 C CA  . GLY D 1 41  ? 9.898   96.619  0.223   1.00 29.10  ? 41  GLY D CA  1 
ATOM   10962 C C   . GLY D 1 41  ? 11.145  96.953  -0.597  1.00 27.63  ? 41  GLY D C   1 
ATOM   10963 O O   . GLY D 1 41  ? 11.874  96.044  -0.977  1.00 27.40  ? 41  GLY D O   1 
ATOM   10964 N N   . MET D 1 42  ? 11.407  98.248  -0.812  1.00 27.90  ? 42  MET D N   1 
ATOM   10965 C CA  . MET D 1 42  ? 12.611  98.724  -1.476  1.00 30.62  ? 42  MET D CA  1 
ATOM   10966 C C   . MET D 1 42  ? 12.639  98.382  -2.973  1.00 31.47  ? 42  MET D C   1 
ATOM   10967 O O   . MET D 1 42  ? 13.655  98.563  -3.621  1.00 32.44  ? 42  MET D O   1 
ATOM   10968 C CB  . MET D 1 42  ? 13.875  98.156  -0.821  1.00 31.68  ? 42  MET D CB  1 
ATOM   10969 C CG  . MET D 1 42  ? 13.970  98.354  0.685   1.00 33.69  ? 42  MET D CG  1 
ATOM   10970 S SD  . MET D 1 42  ? 15.679  98.185  1.238   1.00 35.21  ? 42  MET D SD  1 
ATOM   10971 C CE  . MET D 1 42  ? 15.414  98.477  2.996   1.00 38.62  ? 42  MET D CE  1 
ATOM   10972 N N   . ARG D 1 43  ? 11.546  97.888  -3.547  1.00 35.03  ? 43  ARG D N   1 
ATOM   10973 C CA  . ARG D 1 43  ? 11.510  97.574  -4.967  1.00 38.21  ? 43  ARG D CA  1 
ATOM   10974 C C   . ARG D 1 43  ? 12.269  98.629  -5.791  1.00 37.78  ? 43  ARG D C   1 
ATOM   10975 O O   . ARG D 1 43  ? 11.871  99.788  -5.865  1.00 37.27  ? 43  ARG D O   1 
ATOM   10976 C CB  . ARG D 1 43  ? 10.024  97.513  -5.318  1.00 43.67  ? 43  ARG D CB  1 
ATOM   10977 C CG  . ARG D 1 43  ? 9.613   96.836  -6.613  1.00 50.99  ? 43  ARG D CG  1 
ATOM   10978 C CD  . ARG D 1 43  ? 8.179   97.255  -7.001  1.00 54.65  ? 43  ARG D CD  1 
ATOM   10979 N NE  . ARG D 1 43  ? 7.638   96.231  -7.897  1.00 62.51  ? 43  ARG D NE  1 
ATOM   10980 C CZ  . ARG D 1 43  ? 7.221   95.038  -7.489  1.00 61.56  ? 43  ARG D CZ  1 
ATOM   10981 N NH1 . ARG D 1 43  ? 7.422   93.978  -8.245  1.00 60.44  ? 43  ARG D NH1 1 
ATOM   10982 N NH2 . ARG D 1 43  ? 6.769   94.871  -6.267  1.00 59.20  ? 43  ARG D NH2 1 
ATOM   10983 N N   . GLY D 1 44  ? 13.389  98.227  -6.409  1.00 35.18  ? 44  GLY D N   1 
ATOM   10984 C CA  . GLY D 1 44  ? 14.090  99.060  -7.381  1.00 37.56  ? 44  GLY D CA  1 
ATOM   10985 C C   . GLY D 1 44  ? 15.253  99.858  -6.782  1.00 37.50  ? 44  GLY D C   1 
ATOM   10986 O O   . GLY D 1 44  ? 16.063  100.437 -7.505  1.00 35.20  ? 44  GLY D O   1 
ATOM   10987 N N   . LEU D 1 45  ? 15.342  99.880  -5.450  1.00 36.54  ? 45  LEU D N   1 
ATOM   10988 C CA  . LEU D 1 45  ? 16.290  100.746 -4.782  1.00 35.65  ? 45  LEU D CA  1 
ATOM   10989 C C   . LEU D 1 45  ? 17.689  100.133 -4.820  1.00 34.69  ? 45  LEU D C   1 
ATOM   10990 O O   . LEU D 1 45  ? 17.909  99.006  -4.376  1.00 31.62  ? 45  LEU D O   1 
ATOM   10991 C CB  . LEU D 1 45  ? 15.781  100.970 -3.363  1.00 34.92  ? 45  LEU D CB  1 
ATOM   10992 C CG  . LEU D 1 45  ? 16.432  102.138 -2.618  1.00 36.69  ? 45  LEU D CG  1 
ATOM   10993 C CD1 . LEU D 1 45  ? 16.517  103.442 -3.417  1.00 37.01  ? 45  LEU D CD1 1 
ATOM   10994 C CD2 . LEU D 1 45  ? 15.649  102.371 -1.340  1.00 37.18  ? 45  LEU D CD2 1 
ATOM   10995 N N   . LYS D 1 46  ? 18.656  100.910 -5.325  1.00 39.89  ? 46  LYS D N   1 
ATOM   10996 C CA  . LYS D 1 46  ? 20.016  100.418 -5.512  1.00 39.80  ? 46  LYS D CA  1 
ATOM   10997 C C   . LYS D 1 46  ? 20.766  100.547 -4.196  1.00 34.24  ? 46  LYS D C   1 
ATOM   10998 O O   . LYS D 1 46  ? 21.589  101.435 -4.040  1.00 35.13  ? 46  LYS D O   1 
ATOM   10999 C CB  . LYS D 1 46  ? 20.647  101.114 -6.722  1.00 42.19  ? 46  LYS D CB  1 
ATOM   11000 C CG  . LYS D 1 46  ? 19.979  100.690 -8.029  1.00 41.33  ? 46  LYS D CG  1 
ATOM   11001 C CD  . LYS D 1 46  ? 20.386  101.514 -9.240  1.00 46.49  ? 46  LYS D CD  1 
ATOM   11002 C CE  . LYS D 1 46  ? 19.793  100.988 -10.517 1.00 46.36  ? 46  LYS D CE  1 
ATOM   11003 N NZ  . LYS D 1 46  ? 20.352  101.772 -11.622 1.00 49.34  ? 46  LYS D NZ  1 
ATOM   11004 N N   . ALA D 1 47  ? 20.458  99.628  -3.271  1.00 33.86  ? 47  ALA D N   1 
ATOM   11005 C CA  . ALA D 1 47  ? 20.787  99.788  -1.858  1.00 35.94  ? 47  ALA D CA  1 
ATOM   11006 C C   . ALA D 1 47  ? 21.929  98.857  -1.434  1.00 31.05  ? 47  ALA D C   1 
ATOM   11007 O O   . ALA D 1 47  ? 22.510  99.041  -0.370  1.00 28.79  ? 47  ALA D O   1 
ATOM   11008 C CB  . ALA D 1 47  ? 19.529  99.580  -1.018  1.00 33.70  ? 47  ALA D CB  1 
ATOM   11009 N N   . LEU D 1 48  ? 22.306  97.936  -2.322  1.00 32.32  ? 48  LEU D N   1 
ATOM   11010 C CA  . LEU D 1 48  ? 23.119  96.774  -1.999  1.00 35.15  ? 48  LEU D CA  1 
ATOM   11011 C C   . LEU D 1 48  ? 24.203  96.601  -3.056  1.00 33.14  ? 48  LEU D C   1 
ATOM   11012 O O   . LEU D 1 48  ? 24.015  97.037  -4.184  1.00 32.41  ? 48  LEU D O   1 
ATOM   11013 C CB  . LEU D 1 48  ? 22.213  95.539  -2.051  1.00 38.47  ? 48  LEU D CB  1 
ATOM   11014 C CG  . LEU D 1 48  ? 21.349  95.233  -0.836  1.00 39.80  ? 48  LEU D CG  1 
ATOM   11015 C CD1 . LEU D 1 48  ? 20.660  93.890  -1.018  1.00 40.57  ? 48  LEU D CD1 1 
ATOM   11016 C CD2 . LEU D 1 48  ? 22.229  95.223  0.390   1.00 42.45  ? 48  LEU D CD2 1 
ATOM   11017 N N   . VAL D 1 49  ? 25.243  95.831  -2.717  1.00 30.53  ? 49  VAL D N   1 
ATOM   11018 C CA  . VAL D 1 49  ? 26.277  95.446  -3.654  1.00 29.60  ? 49  VAL D CA  1 
ATOM   11019 C C   . VAL D 1 49  ? 26.370  93.923  -3.731  1.00 30.00  ? 49  VAL D C   1 
ATOM   11020 O O   . VAL D 1 49  ? 26.413  93.236  -2.711  1.00 25.20  ? 49  VAL D O   1 
ATOM   11021 C CB  . VAL D 1 49  ? 27.617  96.067  -3.236  1.00 33.88  ? 49  VAL D CB  1 
ATOM   11022 C CG1 . VAL D 1 49  ? 28.783  95.457  -4.022  1.00 35.37  ? 49  VAL D CG1 1 
ATOM   11023 C CG2 . VAL D 1 49  ? 27.582  97.594  -3.353  1.00 34.46  ? 49  VAL D CG2 1 
ATOM   11024 N N   . CYS D 1 50  ? 26.412  93.397  -4.971  1.00 30.65  ? 50  CYS D N   1 
ATOM   11025 C CA  . CYS D 1 50  ? 26.632  91.976  -5.195  1.00 25.68  ? 50  CYS D CA  1 
ATOM   11026 C C   . CYS D 1 50  ? 27.445  91.824  -6.468  1.00 24.96  ? 50  CYS D C   1 
ATOM   11027 O O   . CYS D 1 50  ? 27.045  92.298  -7.521  1.00 29.46  ? 50  CYS D O   1 
ATOM   11028 C CB  . CYS D 1 50  ? 25.315  91.214  -5.248  1.00 24.29  ? 50  CYS D CB  1 
ATOM   11029 S SG  . CYS D 1 50  ? 25.528  89.462  -5.668  1.00 26.86  ? 50  CYS D SG  1 
ATOM   11030 N N   . ASP D 1 51  ? 28.599  91.185  -6.358  1.00 25.41  ? 51  ASP D N   1 
ATOM   11031 C CA  . ASP D 1 51  ? 29.444  90.960  -7.514  1.00 26.05  ? 51  ASP D CA  1 
ATOM   11032 C C   . ASP D 1 51  ? 29.342  89.509  -7.987  1.00 28.62  ? 51  ASP D C   1 
ATOM   11033 O O   . ASP D 1 51  ? 29.933  89.157  -9.011  1.00 30.93  ? 51  ASP D O   1 
ATOM   11034 C CB  . ASP D 1 51  ? 30.861  91.426  -7.238  1.00 25.04  ? 51  ASP D CB  1 
ATOM   11035 C CG  . ASP D 1 51  ? 31.011  92.942  -7.293  1.00 26.83  ? 51  ASP D CG  1 
ATOM   11036 O OD1 . ASP D 1 51  ? 30.305  93.556  -8.099  1.00 28.64  ? 51  ASP D OD1 1 
ATOM   11037 O OD2 . ASP D 1 51  ? 31.833  93.512  -6.541  1.00 26.50  ? 51  ASP D OD2 1 
ATOM   11038 N N   . THR D 1 52  ? 28.575  88.669  -7.277  1.00 25.61  ? 52  THR D N   1 
ATOM   11039 C CA  . THR D 1 52  ? 28.498  87.270  -7.660  1.00 26.08  ? 52  THR D CA  1 
ATOM   11040 C C   . THR D 1 52  ? 27.635  87.115  -8.912  1.00 26.39  ? 52  THR D C   1 
ATOM   11041 O O   . THR D 1 52  ? 27.965  86.307  -9.777  1.00 23.89  ? 52  THR D O   1 
ATOM   11042 C CB  . THR D 1 52  ? 28.001  86.373  -6.524  1.00 24.37  ? 52  THR D CB  1 
ATOM   11043 O OG1 . THR D 1 52  ? 26.773  86.840  -5.976  1.00 21.57  ? 52  THR D OG1 1 
ATOM   11044 C CG2 . THR D 1 52  ? 29.052  86.243  -5.438  1.00 25.61  ? 52  THR D CG2 1 
ATOM   11045 N N   . SER D 1 53  ? 26.509  87.843  -8.959  1.00 30.00  ? 53  SER D N   1 
ATOM   11046 C CA  . SER D 1 53  ? 25.512  87.682  -10.007 1.00 31.05  ? 53  SER D CA  1 
ATOM   11047 C C   . SER D 1 53  ? 24.697  88.965  -10.164 1.00 32.36  ? 53  SER D C   1 
ATOM   11048 O O   . SER D 1 53  ? 24.611  89.789  -9.251  1.00 32.54  ? 53  SER D O   1 
ATOM   11049 C CB  . SER D 1 53  ? 24.617  86.492  -9.750  1.00 31.57  ? 53  SER D CB  1 
ATOM   11050 O OG  . SER D 1 53  ? 23.756  86.723  -8.638  1.00 30.30  ? 53  SER D OG  1 
ATOM   11051 N N   . GLU D 1 54  ? 24.123  89.114  -11.364 1.00 36.12  ? 54  GLU D N   1 
ATOM   11052 C CA  . GLU D 1 54  ? 23.287  90.253  -11.722 1.00 37.54  ? 54  GLU D CA  1 
ATOM   11053 C C   . GLU D 1 54  ? 22.060  89.783  -12.507 1.00 32.64  ? 54  GLU D C   1 
ATOM   11054 O O   . GLU D 1 54  ? 22.170  88.964  -13.412 1.00 30.34  ? 54  GLU D O   1 
ATOM   11055 C CB  . GLU D 1 54  ? 24.157  91.194  -12.557 1.00 42.42  ? 54  GLU D CB  1 
ATOM   11056 C CG  . GLU D 1 54  ? 23.443  92.477  -12.980 1.00 41.86  ? 54  GLU D CG  1 
ATOM   11057 C CD  . GLU D 1 54  ? 24.373  93.528  -13.548 1.00 39.69  ? 54  GLU D CD  1 
ATOM   11058 O OE1 . GLU D 1 54  ? 23.881  94.683  -13.562 1.00 40.73  ? 54  GLU D OE1 1 
ATOM   11059 O OE2 . GLU D 1 54  ? 25.532  93.198  -13.954 1.00 33.58  ? 54  GLU D OE2 1 
ATOM   11060 N N   . VAL D 1 55  ? 20.883  90.307  -12.176 1.00 34.43  ? 55  VAL D N   1 
ATOM   11061 C CA  . VAL D 1 55  ? 19.671  89.830  -12.818 1.00 36.58  ? 55  VAL D CA  1 
ATOM   11062 C C   . VAL D 1 55  ? 19.200  90.901  -13.782 1.00 35.07  ? 55  VAL D C   1 
ATOM   11063 O O   . VAL D 1 55  ? 18.750  91.952  -13.334 1.00 36.63  ? 55  VAL D O   1 
ATOM   11064 C CB  . VAL D 1 55  ? 18.587  89.461  -11.800 1.00 38.83  ? 55  VAL D CB  1 
ATOM   11065 C CG1 . VAL D 1 55  ? 17.302  89.014  -12.484 1.00 43.68  ? 55  VAL D CG1 1 
ATOM   11066 C CG2 . VAL D 1 55  ? 19.084  88.358  -10.880 1.00 40.88  ? 55  VAL D CG2 1 
ATOM   11067 N N   . PHE D 1 56  ? 19.398  90.628  -15.080 1.00 35.32  ? 56  PHE D N   1 
ATOM   11068 C CA  . PHE D 1 56  ? 19.043  91.526  -16.165 1.00 38.70  ? 56  PHE D CA  1 
ATOM   11069 C C   . PHE D 1 56  ? 17.563  91.382  -16.501 1.00 40.12  ? 56  PHE D C   1 
ATOM   11070 O O   . PHE D 1 56  ? 17.141  90.280  -16.822 1.00 46.26  ? 56  PHE D O   1 
ATOM   11071 C CB  . PHE D 1 56  ? 19.895  91.159  -17.380 1.00 38.59  ? 56  PHE D CB  1 
ATOM   11072 C CG  . PHE D 1 56  ? 21.334  91.644  -17.287 1.00 43.78  ? 56  PHE D CG  1 
ATOM   11073 C CD1 . PHE D 1 56  ? 22.285  90.900  -16.597 1.00 39.97  ? 56  PHE D CD1 1 
ATOM   11074 C CD2 . PHE D 1 56  ? 21.734  92.841  -17.894 1.00 43.98  ? 56  PHE D CD2 1 
ATOM   11075 C CE1 . PHE D 1 56  ? 23.597  91.332  -16.515 1.00 37.51  ? 56  PHE D CE1 1 
ATOM   11076 C CE2 . PHE D 1 56  ? 23.048  93.269  -17.805 1.00 42.02  ? 56  PHE D CE2 1 
ATOM   11077 C CZ  . PHE D 1 56  ? 23.978  92.510  -17.122 1.00 40.87  ? 56  PHE D CZ  1 
ATOM   11078 N N   . PRO D 1 57  ? 16.723  92.449  -16.486 1.00 48.58  ? 57  PRO D N   1 
ATOM   11079 C CA  . PRO D 1 57  ? 15.290  92.266  -16.729 1.00 47.24  ? 57  PRO D CA  1 
ATOM   11080 C C   . PRO D 1 57  ? 14.979  91.554  -18.046 1.00 43.88  ? 57  PRO D C   1 
ATOM   11081 O O   . PRO D 1 57  ? 14.076  90.721  -18.094 1.00 44.48  ? 57  PRO D O   1 
ATOM   11082 C CB  . PRO D 1 57  ? 14.737  93.705  -16.658 1.00 45.66  ? 57  PRO D CB  1 
ATOM   11083 C CG  . PRO D 1 57  ? 15.719  94.413  -15.750 1.00 48.86  ? 57  PRO D CG  1 
ATOM   11084 C CD  . PRO D 1 57  ? 17.064  93.867  -16.244 1.00 49.68  ? 57  PRO D CD  1 
ATOM   11085 N N   . ASP D 1 58  ? 15.761  91.837  -19.095 1.00 44.67  ? 58  ASP D N   1 
ATOM   11086 C CA  . ASP D 1 58  ? 15.440  91.347  -20.425 1.00 47.80  ? 58  ASP D CA  1 
ATOM   11087 C C   . ASP D 1 58  ? 16.327  90.162  -20.807 1.00 50.54  ? 58  ASP D C   1 
ATOM   11088 O O   . ASP D 1 58  ? 16.282  89.772  -21.972 1.00 47.10  ? 58  ASP D O   1 
ATOM   11089 C CB  . ASP D 1 58  ? 15.610  92.417  -21.502 1.00 54.13  ? 58  ASP D CB  1 
ATOM   11090 C CG  . ASP D 1 58  ? 14.791  93.699  -21.373 1.00 58.39  ? 58  ASP D CG  1 
ATOM   11091 O OD1 . ASP D 1 58  ? 13.773  93.691  -20.641 1.00 61.42  ? 58  ASP D OD1 1 
ATOM   11092 O OD2 . ASP D 1 58  ? 15.196  94.716  -21.988 1.00 55.22  ? 58  ASP D OD2 1 
ATOM   11093 N N   . GLU D 1 59  ? 17.144  89.606  -19.881 1.00 45.83  ? 59  GLU D N   1 
ATOM   11094 C CA  . GLU D 1 59  ? 18.028  88.490  -20.237 1.00 45.66  ? 59  GLU D CA  1 
ATOM   11095 C C   . GLU D 1 59  ? 18.044  87.361  -19.200 1.00 46.87  ? 59  GLU D C   1 
ATOM   11096 O O   . GLU D 1 59  ? 18.155  86.177  -19.555 1.00 44.47  ? 59  GLU D O   1 
ATOM   11097 C CB  . GLU D 1 59  ? 19.443  88.988  -20.517 1.00 48.03  ? 59  GLU D CB  1 
ATOM   11098 C CG  . GLU D 1 59  ? 19.488  90.038  -21.626 1.00 49.21  ? 59  GLU D CG  1 
ATOM   11099 C CD  . GLU D 1 59  ? 20.888  90.539  -21.839 1.00 49.97  ? 59  GLU D CD  1 
ATOM   11100 O OE1 . GLU D 1 59  ? 21.731  89.655  -22.085 1.00 43.60  ? 59  GLU D OE1 1 
ATOM   11101 O OE2 . GLU D 1 59  ? 21.111  91.766  -21.689 1.00 57.76  ? 59  GLU D OE2 1 
ATOM   11102 N N   . GLY D 1 60  ? 17.948  87.738  -17.919 1.00 43.17  ? 60  GLY D N   1 
ATOM   11103 C CA  . GLY D 1 60  ? 17.979  86.778  -16.836 1.00 40.45  ? 60  GLY D CA  1 
ATOM   11104 C C   . GLY D 1 60  ? 19.260  86.918  -16.022 1.00 35.62  ? 60  GLY D C   1 
ATOM   11105 O O   . GLY D 1 60  ? 19.949  87.931  -16.088 1.00 29.42  ? 60  GLY D O   1 
ATOM   11106 N N   . VAL D 1 61  ? 19.575  85.877  -15.256 1.00 31.96  ? 61  VAL D N   1 
ATOM   11107 C CA  . VAL D 1 61  ? 20.681  85.987  -14.333 1.00 32.26  ? 61  VAL D CA  1 
ATOM   11108 C C   . VAL D 1 61  ? 21.978  85.845  -15.118 1.00 29.61  ? 61  VAL D C   1 
ATOM   11109 O O   . VAL D 1 61  ? 22.067  85.061  -16.057 1.00 28.60  ? 61  VAL D O   1 
ATOM   11110 C CB  . VAL D 1 61  ? 20.612  85.013  -13.135 1.00 32.15  ? 61  VAL D CB  1 
ATOM   11111 C CG1 . VAL D 1 61  ? 20.753  83.546  -13.533 1.00 33.76  ? 61  VAL D CG1 1 
ATOM   11112 C CG2 . VAL D 1 61  ? 21.645  85.375  -12.074 1.00 30.69  ? 61  VAL D CG2 1 
ATOM   11113 N N   . LYS D 1 62  ? 23.006  86.575  -14.682 1.00 31.71  ? 62  LYS D N   1 
ATOM   11114 C CA  . LYS D 1 62  ? 24.347  86.298  -15.168 1.00 36.31  ? 62  LYS D CA  1 
ATOM   11115 C C   . LYS D 1 62  ? 25.271  86.126  -13.974 1.00 33.36  ? 62  LYS D C   1 
ATOM   11116 O O   . LYS D 1 62  ? 25.310  86.961  -13.070 1.00 33.87  ? 62  LYS D O   1 
ATOM   11117 C CB  . LYS D 1 62  ? 24.903  87.341  -16.149 1.00 40.75  ? 62  LYS D CB  1 
ATOM   11118 C CG  . LYS D 1 62  ? 24.052  87.564  -17.394 1.00 40.91  ? 62  LYS D CG  1 
ATOM   11119 C CD  . LYS D 1 62  ? 24.623  88.650  -18.302 1.00 45.38  ? 62  LYS D CD  1 
ATOM   11120 C CE  . LYS D 1 62  ? 23.819  88.870  -19.546 1.00 48.67  ? 62  LYS D CE  1 
ATOM   11121 N NZ  . LYS D 1 62  ? 24.618  89.558  -20.558 1.00 52.86  ? 62  LYS D NZ  1 
ATOM   11122 N N   . PHE D 1 63  ? 26.013  85.020  -14.027 1.00 32.02  ? 63  PHE D N   1 
ATOM   11123 C CA  . PHE D 1 63  ? 26.995  84.660  -13.030 1.00 29.85  ? 63  PHE D CA  1 
ATOM   11124 C C   . PHE D 1 63  ? 28.362  85.187  -13.443 1.00 29.51  ? 63  PHE D C   1 
ATOM   11125 O O   . PHE D 1 63  ? 28.980  84.597  -14.327 1.00 28.40  ? 63  PHE D O   1 
ATOM   11126 C CB  . PHE D 1 63  ? 26.979  83.133  -13.010 1.00 29.07  ? 63  PHE D CB  1 
ATOM   11127 C CG  . PHE D 1 63  ? 25.702  82.475  -12.516 1.00 30.13  ? 63  PHE D CG  1 
ATOM   11128 C CD1 . PHE D 1 63  ? 25.030  82.947  -11.386 1.00 33.44  ? 63  PHE D CD1 1 
ATOM   11129 C CD2 . PHE D 1 63  ? 25.211  81.330  -13.139 1.00 30.41  ? 63  PHE D CD2 1 
ATOM   11130 C CE1 . PHE D 1 63  ? 23.883  82.312  -10.908 1.00 30.91  ? 63  PHE D CE1 1 
ATOM   11131 C CE2 . PHE D 1 63  ? 24.058  80.710  -12.663 1.00 31.47  ? 63  PHE D CE2 1 
ATOM   11132 C CZ  . PHE D 1 63  ? 23.403  81.199  -11.543 1.00 29.85  ? 63  PHE D CZ  1 
ATOM   11133 N N   . ARG D 1 64  ? 28.828  86.268  -12.785 1.00 31.78  ? 64  ARG D N   1 
ATOM   11134 C CA  . ARG D 1 64  ? 30.095  86.922  -13.110 1.00 31.43  ? 64  ARG D CA  1 
ATOM   11135 C C   . ARG D 1 64  ? 30.184  87.172  -14.621 1.00 32.74  ? 64  ARG D C   1 
ATOM   11136 O O   . ARG D 1 64  ? 31.188  86.841  -15.248 1.00 30.79  ? 64  ARG D O   1 
ATOM   11137 C CB  . ARG D 1 64  ? 31.313  86.093  -12.690 1.00 32.27  ? 64  ARG D CB  1 
ATOM   11138 C CG  . ARG D 1 64  ? 31.575  85.908  -11.198 1.00 33.44  ? 64  ARG D CG  1 
ATOM   11139 C CD  . ARG D 1 64  ? 32.115  87.156  -10.590 1.00 31.84  ? 64  ARG D CD  1 
ATOM   11140 N NE  . ARG D 1 64  ? 32.463  87.028  -9.172  1.00 31.18  ? 64  ARG D NE  1 
ATOM   11141 C CZ  . ARG D 1 64  ? 33.196  87.956  -8.545  1.00 33.13  ? 64  ARG D CZ  1 
ATOM   11142 N NH1 . ARG D 1 64  ? 33.443  89.091  -9.162  1.00 32.05  ? 64  ARG D NH1 1 
ATOM   11143 N NH2 . ARG D 1 64  ? 33.699  87.788  -7.323  1.00 35.07  ? 64  ARG D NH2 1 
ATOM   11144 N N   . GLY D 1 65  ? 29.111  87.732  -15.203 1.00 32.35  ? 65  GLY D N   1 
ATOM   11145 C CA  . GLY D 1 65  ? 29.104  88.123  -16.603 1.00 33.74  ? 65  GLY D CA  1 
ATOM   11146 C C   . GLY D 1 65  ? 28.680  86.998  -17.547 1.00 35.26  ? 65  GLY D C   1 
ATOM   11147 O O   . GLY D 1 65  ? 28.443  87.258  -18.716 1.00 42.43  ? 65  GLY D O   1 
ATOM   11148 N N   . TYR D 1 66  ? 28.533  85.769  -17.049 1.00 33.42  ? 66  TYR D N   1 
ATOM   11149 C CA  . TYR D 1 66  ? 28.306  84.608  -17.890 1.00 29.06  ? 66  TYR D CA  1 
ATOM   11150 C C   . TYR D 1 66  ? 26.873  84.112  -17.772 1.00 30.00  ? 66  TYR D C   1 
ATOM   11151 O O   . TYR D 1 66  ? 26.366  83.942  -16.666 1.00 30.51  ? 66  TYR D O   1 
ATOM   11152 C CB  . TYR D 1 66  ? 29.179  83.439  -17.440 1.00 30.40  ? 66  TYR D CB  1 
ATOM   11153 C CG  . TYR D 1 66  ? 30.664  83.658  -17.666 1.00 34.14  ? 66  TYR D CG  1 
ATOM   11154 C CD1 . TYR D 1 66  ? 31.226  83.427  -18.925 1.00 38.06  ? 66  TYR D CD1 1 
ATOM   11155 C CD2 . TYR D 1 66  ? 31.495  84.110  -16.652 1.00 30.67  ? 66  TYR D CD2 1 
ATOM   11156 C CE1 . TYR D 1 66  ? 32.569  83.637  -19.172 1.00 33.63  ? 66  TYR D CE1 1 
ATOM   11157 C CE2 . TYR D 1 66  ? 32.850  84.288  -16.880 1.00 33.70  ? 66  TYR D CE2 1 
ATOM   11158 C CZ  . TYR D 1 66  ? 33.378  84.058  -18.140 1.00 34.17  ? 66  TYR D CZ  1 
ATOM   11159 O OH  . TYR D 1 66  ? 34.690  84.204  -18.398 1.00 32.84  ? 66  TYR D OH  1 
ATOM   11160 N N   . THR D 1 67  ? 26.260  83.798  -18.921 1.00 28.81  ? 67  THR D N   1 
ATOM   11161 C CA  . THR D 1 67  ? 24.887  83.331  -18.968 1.00 25.72  ? 67  THR D CA  1 
ATOM   11162 C C   . THR D 1 67  ? 24.888  81.850  -18.608 1.00 25.03  ? 67  THR D C   1 
ATOM   11163 O O   . THR D 1 67  ? 25.925  81.195  -18.688 1.00 22.79  ? 67  THR D O   1 
ATOM   11164 C CB  . THR D 1 67  ? 24.289  83.603  -20.359 1.00 24.77  ? 67  THR D CB  1 
ATOM   11165 O OG1 . THR D 1 67  ? 24.952  82.801  -21.337 1.00 23.93  ? 67  THR D OG1 1 
ATOM   11166 C CG2 . THR D 1 67  ? 24.355  85.067  -20.759 1.00 22.12  ? 67  THR D CG2 1 
ATOM   11167 N N   . ILE D 1 68  ? 23.706  81.336  -18.254 1.00 26.18  ? 68  ILE D N   1 
ATOM   11168 C CA  . ILE D 1 68  ? 23.488  79.916  -18.026 1.00 28.86  ? 68  ILE D CA  1 
ATOM   11169 C C   . ILE D 1 68  ? 23.842  79.084  -19.262 1.00 30.28  ? 68  ILE D C   1 
ATOM   11170 O O   . ILE D 1 68  ? 24.626  78.124  -19.166 1.00 27.75  ? 68  ILE D O   1 
ATOM   11171 C CB  . ILE D 1 68  ? 22.053  79.696  -17.534 1.00 32.15  ? 68  ILE D CB  1 
ATOM   11172 C CG1 . ILE D 1 68  ? 21.935  80.161  -16.088 1.00 36.54  ? 68  ILE D CG1 1 
ATOM   11173 C CG2 . ILE D 1 68  ? 21.645  78.236  -17.724 1.00 33.53  ? 68  ILE D CG2 1 
ATOM   11174 C CD1 . ILE D 1 68  ? 20.522  80.251  -15.539 1.00 39.49  ? 68  ILE D CD1 1 
ATOM   11175 N N   . PRO D 1 69  ? 23.313  79.416  -20.475 1.00 34.57  ? 69  PRO D N   1 
ATOM   11176 C CA  . PRO D 1 69  ? 23.691  78.676  -21.687 1.00 29.26  ? 69  PRO D CA  1 
ATOM   11177 C C   . PRO D 1 69  ? 25.197  78.667  -21.918 1.00 28.09  ? 69  PRO D C   1 
ATOM   11178 O O   . PRO D 1 69  ? 25.784  77.614  -22.177 1.00 29.60  ? 69  PRO D O   1 
ATOM   11179 C CB  . PRO D 1 69  ? 22.929  79.413  -22.777 1.00 29.06  ? 69  PRO D CB  1 
ATOM   11180 C CG  . PRO D 1 69  ? 21.733  79.991  -22.054 1.00 29.98  ? 69  PRO D CG  1 
ATOM   11181 C CD  . PRO D 1 69  ? 22.331  80.487  -20.761 1.00 29.62  ? 69  PRO D CD  1 
ATOM   11182 N N   . GLU D 1 70  ? 25.827  79.841  -21.777 1.00 27.74  ? 70  GLU D N   1 
ATOM   11183 C CA  . GLU D 1 70  ? 27.283  79.936  -21.877 1.00 30.73  ? 70  GLU D CA  1 
ATOM   11184 C C   . GLU D 1 70  ? 27.994  78.908  -20.988 1.00 30.27  ? 70  GLU D C   1 
ATOM   11185 O O   . GLU D 1 70  ? 29.015  78.392  -21.408 1.00 29.01  ? 70  GLU D O   1 
ATOM   11186 C CB  . GLU D 1 70  ? 27.815  81.346  -21.576 1.00 32.69  ? 70  GLU D CB  1 
ATOM   11187 C CG  . GLU D 1 70  ? 27.704  82.307  -22.755 1.00 33.55  ? 70  GLU D CG  1 
ATOM   11188 C CD  . GLU D 1 70  ? 28.170  83.715  -22.443 1.00 38.29  ? 70  GLU D CD  1 
ATOM   11189 O OE1 . GLU D 1 70  ? 28.996  84.222  -23.220 1.00 48.56  ? 70  GLU D OE1 1 
ATOM   11190 O OE2 . GLU D 1 70  ? 27.741  84.311  -21.439 1.00 39.03  ? 70  GLU D OE2 1 
ATOM   11191 N N   . LEU D 1 71  ? 27.481  78.639  -19.760 1.00 30.77  ? 71  LEU D N   1 
ATOM   11192 C CA  . LEU D 1 71  ? 28.163  77.804  -18.782 1.00 27.48  ? 71  LEU D CA  1 
ATOM   11193 C C   . LEU D 1 71  ? 27.669  76.358  -18.783 1.00 26.99  ? 71  LEU D C   1 
ATOM   11194 O O   . LEU D 1 71  ? 28.382  75.467  -18.312 1.00 25.03  ? 71  LEU D O   1 
ATOM   11195 C CB  . LEU D 1 71  ? 27.980  78.418  -17.403 1.00 28.32  ? 71  LEU D CB  1 
ATOM   11196 C CG  . LEU D 1 71  ? 28.676  79.756  -17.181 1.00 26.89  ? 71  LEU D CG  1 
ATOM   11197 C CD1 . LEU D 1 71  ? 28.013  80.412  -15.976 1.00 28.67  ? 71  LEU D CD1 1 
ATOM   11198 C CD2 . LEU D 1 71  ? 30.158  79.562  -16.979 1.00 26.88  ? 71  LEU D CD2 1 
ATOM   11199 N N   . ARG D 1 72  ? 26.457  76.130  -19.297 1.00 26.42  ? 72  ARG D N   1 
ATOM   11200 C CA  . ARG D 1 72  ? 25.926  74.776  -19.375 1.00 29.43  ? 72  ARG D CA  1 
ATOM   11201 C C   . ARG D 1 72  ? 26.147  74.127  -20.749 1.00 28.79  ? 72  ARG D C   1 
ATOM   11202 O O   . ARG D 1 72  ? 26.244  72.913  -20.829 1.00 27.74  ? 72  ARG D O   1 
ATOM   11203 C CB  . ARG D 1 72  ? 24.424  74.816  -19.056 1.00 29.70  ? 72  ARG D CB  1 
ATOM   11204 C CG  . ARG D 1 72  ? 23.673  73.490  -19.133 1.00 30.85  ? 72  ARG D CG  1 
ATOM   11205 C CD  . ARG D 1 72  ? 22.296  73.544  -18.439 1.00 30.00  ? 72  ARG D CD  1 
ATOM   11206 N NE  . ARG D 1 72  ? 21.640  72.249  -18.605 1.00 30.34  ? 72  ARG D NE  1 
ATOM   11207 C CZ  . ARG D 1 72  ? 21.098  71.841  -19.740 1.00 33.77  ? 72  ARG D CZ  1 
ATOM   11208 N NH1 . ARG D 1 72  ? 20.911  72.685  -20.739 1.00 37.99  ? 72  ARG D NH1 1 
ATOM   11209 N NH2 . ARG D 1 72  ? 20.665  70.606  -19.853 1.00 33.12  ? 72  ARG D NH2 1 
ATOM   11210 N N   . GLU D 1 73  ? 26.119  74.925  -21.825 1.00 31.07  ? 73  GLU D N   1 
ATOM   11211 C CA  . GLU D 1 73  ? 26.113  74.417  -23.190 1.00 34.64  ? 73  GLU D CA  1 
ATOM   11212 C C   . GLU D 1 73  ? 27.426  74.763  -23.905 1.00 30.97  ? 73  GLU D C   1 
ATOM   11213 O O   . GLU D 1 73  ? 27.982  73.948  -24.633 1.00 29.81  ? 73  GLU D O   1 
ATOM   11214 C CB  . GLU D 1 73  ? 24.905  74.994  -23.937 1.00 39.26  ? 73  GLU D CB  1 
ATOM   11215 C CG  . GLU D 1 73  ? 23.554  74.494  -23.434 1.00 44.67  ? 73  GLU D CG  1 
ATOM   11216 C CD  . GLU D 1 73  ? 22.368  75.370  -23.809 1.00 48.74  ? 73  GLU D CD  1 
ATOM   11217 O OE1 . GLU D 1 73  ? 21.271  74.987  -23.366 1.00 64.34  ? 73  GLU D OE1 1 
ATOM   11218 O OE2 . GLU D 1 73  ? 22.488  76.390  -24.526 1.00 41.47  ? 73  GLU D OE2 1 
ATOM   11219 N N   . GLY D 1 74  ? 27.914  75.981  -23.666 1.00 32.04  ? 74  GLY D N   1 
ATOM   11220 C CA  . GLY D 1 74  ? 29.105  76.539  -24.289 1.00 31.59  ? 74  GLY D CA  1 
ATOM   11221 C C   . GLY D 1 74  ? 28.839  77.957  -24.798 1.00 31.11  ? 74  GLY D C   1 
ATOM   11222 O O   . GLY D 1 74  ? 27.700  78.447  -24.793 1.00 29.91  ? 74  GLY D O   1 
ATOM   11223 N N   . PRO D 1 75  ? 29.873  78.689  -25.255 1.00 33.85  ? 75  PRO D N   1 
ATOM   11224 C CA  . PRO D 1 75  ? 31.238  78.157  -25.363 1.00 36.94  ? 75  PRO D CA  1 
ATOM   11225 C C   . PRO D 1 75  ? 32.175  78.287  -24.158 1.00 36.75  ? 75  PRO D C   1 
ATOM   11226 O O   . PRO D 1 75  ? 33.367  78.137  -24.321 1.00 36.72  ? 75  PRO D O   1 
ATOM   11227 C CB  . PRO D 1 75  ? 31.731  79.042  -26.536 1.00 37.77  ? 75  PRO D CB  1 
ATOM   11228 C CG  . PRO D 1 75  ? 31.146  80.427  -26.227 1.00 36.91  ? 75  PRO D CG  1 
ATOM   11229 C CD  . PRO D 1 75  ? 29.745  80.087  -25.725 1.00 35.88  ? 75  PRO D CD  1 
ATOM   11230 N N   . HIS D 1 76  ? 31.637  78.607  -22.974 1.00 37.16  ? 76  HIS D N   1 
ATOM   11231 C CA  . HIS D 1 76  ? 32.392  78.670  -21.732 1.00 33.98  ? 76  HIS D CA  1 
ATOM   11232 C C   . HIS D 1 76  ? 31.910  77.605  -20.751 1.00 30.60  ? 76  HIS D C   1 
ATOM   11233 O O   . HIS D 1 76  ? 31.758  77.908  -19.591 1.00 29.63  ? 76  HIS D O   1 
ATOM   11234 C CB  . HIS D 1 76  ? 32.186  80.053  -21.107 1.00 34.56  ? 76  HIS D CB  1 
ATOM   11235 C CG  . HIS D 1 76  ? 32.746  81.139  -21.978 1.00 34.76  ? 76  HIS D CG  1 
ATOM   11236 N ND1 . HIS D 1 76  ? 34.092  81.197  -22.311 1.00 29.76  ? 76  HIS D ND1 1 
ATOM   11237 C CD2 . HIS D 1 76  ? 32.158  82.216  -22.536 1.00 31.06  ? 76  HIS D CD2 1 
ATOM   11238 C CE1 . HIS D 1 76  ? 34.302  82.269  -23.059 1.00 32.25  ? 76  HIS D CE1 1 
ATOM   11239 N NE2 . HIS D 1 76  ? 33.148  82.909  -23.194 1.00 33.46  ? 76  HIS D NE2 1 
ATOM   11240 N N   . LYS D 1 77  ? 31.696  76.367  -21.221 1.00 32.30  ? 77  LYS D N   1 
ATOM   11241 C CA  . LYS D 1 77  ? 31.060  75.310  -20.447 1.00 33.90  ? 77  LYS D CA  1 
ATOM   11242 C C   . LYS D 1 77  ? 31.891  74.913  -19.219 1.00 33.45  ? 77  LYS D C   1 
ATOM   11243 O O   . LYS D 1 77  ? 33.060  74.572  -19.350 1.00 35.15  ? 77  LYS D O   1 
ATOM   11244 C CB  . LYS D 1 77  ? 30.881  74.074  -21.334 1.00 34.28  ? 77  LYS D CB  1 
ATOM   11245 C CG  . LYS D 1 77  ? 30.177  72.934  -20.630 1.00 35.68  ? 77  LYS D CG  1 
ATOM   11246 C CD  . LYS D 1 77  ? 29.807  71.767  -21.541 1.00 37.56  ? 77  LYS D CD  1 
ATOM   11247 C CE  . LYS D 1 77  ? 29.134  70.615  -20.854 1.00 33.31  ? 77  LYS D CE  1 
ATOM   11248 N NZ  . LYS D 1 77  ? 27.819  70.993  -20.318 1.00 33.01  ? 77  LYS D NZ  1 
ATOM   11249 N N   . LEU D 1 78  ? 31.271  74.913  -18.031 1.00 29.13  ? 78  LEU D N   1 
ATOM   11250 C CA  . LEU D 1 78  ? 31.960  74.552  -16.800 1.00 27.87  ? 78  LEU D CA  1 
ATOM   11251 C C   . LEU D 1 78  ? 32.274  73.068  -16.796 1.00 26.27  ? 78  LEU D C   1 
ATOM   11252 O O   . LEU D 1 78  ? 31.764  72.318  -17.610 1.00 29.42  ? 78  LEU D O   1 
ATOM   11253 C CB  . LEU D 1 78  ? 31.136  74.880  -15.562 1.00 28.99  ? 78  LEU D CB  1 
ATOM   11254 C CG  . LEU D 1 78  ? 30.908  76.366  -15.306 1.00 30.39  ? 78  LEU D CG  1 
ATOM   11255 C CD1 . LEU D 1 78  ? 29.822  76.523  -14.283 1.00 29.99  ? 78  LEU D CD1 1 
ATOM   11256 C CD2 . LEU D 1 78  ? 32.213  77.034  -14.878 1.00 30.76  ? 78  LEU D CD2 1 
ATOM   11257 N N   . PRO D 1 79  ? 33.177  72.603  -15.913 1.00 26.99  ? 79  PRO D N   1 
ATOM   11258 C CA  . PRO D 1 79  ? 33.403  71.167  -15.760 1.00 28.31  ? 79  PRO D CA  1 
ATOM   11259 C C   . PRO D 1 79  ? 32.208  70.374  -15.247 1.00 26.41  ? 79  PRO D C   1 
ATOM   11260 O O   . PRO D 1 79  ? 31.322  70.900  -14.593 1.00 25.91  ? 79  PRO D O   1 
ATOM   11261 C CB  . PRO D 1 79  ? 34.618  71.084  -14.834 1.00 28.01  ? 79  PRO D CB  1 
ATOM   11262 C CG  . PRO D 1 79  ? 35.326  72.408  -15.077 1.00 28.95  ? 79  PRO D CG  1 
ATOM   11263 C CD  . PRO D 1 79  ? 34.183  73.416  -15.214 1.00 27.61  ? 79  PRO D CD  1 
ATOM   11264 N N   . THR D 1 80  ? 32.201  69.092  -15.598 1.00 26.78  ? 80  THR D N   1 
ATOM   11265 C CA  . THR D 1 80  ? 31.078  68.225  -15.327 1.00 27.79  ? 80  THR D CA  1 
ATOM   11266 C C   . THR D 1 80  ? 31.601  67.127  -14.432 1.00 29.20  ? 80  THR D C   1 
ATOM   11267 O O   . THR D 1 80  ? 32.797  67.037  -14.223 1.00 36.14  ? 80  THR D O   1 
ATOM   11268 C CB  . THR D 1 80  ? 30.504  67.637  -16.619 1.00 26.77  ? 80  THR D CB  1 
ATOM   11269 O OG1 . THR D 1 80  ? 31.442  66.696  -17.124 1.00 26.20  ? 80  THR D OG1 1 
ATOM   11270 C CG2 . THR D 1 80  ? 30.210  68.680  -17.677 1.00 25.57  ? 80  THR D CG2 1 
ATOM   11271 N N   . ALA D 1 81  ? 30.700  66.261  -13.981 1.00 30.12  ? 81  ALA D N   1 
ATOM   11272 C CA  . ALA D 1 81  ? 31.109  64.954  -13.509 1.00 32.07  ? 81  ALA D CA  1 
ATOM   11273 C C   . ALA D 1 81  ? 31.632  64.140  -14.692 1.00 35.20  ? 81  ALA D C   1 
ATOM   11274 O O   . ALA D 1 81  ? 31.246  64.372  -15.845 1.00 33.56  ? 81  ALA D O   1 
ATOM   11275 C CB  . ALA D 1 81  ? 29.944  64.273  -12.837 1.00 34.92  ? 81  ALA D CB  1 
ATOM   11276 N N   . GLU D 1 82  ? 32.496  63.169  -14.387 1.00 36.36  ? 82  GLU D N   1 
ATOM   11277 C CA  . GLU D 1 82  ? 33.006  62.280  -15.407 1.00 38.15  ? 82  GLU D CA  1 
ATOM   11278 C C   . GLU D 1 82  ? 31.836  61.564  -16.074 1.00 36.60  ? 82  GLU D C   1 
ATOM   11279 O O   . GLU D 1 82  ? 31.058  60.880  -15.423 1.00 36.65  ? 82  GLU D O   1 
ATOM   11280 C CB  . GLU D 1 82  ? 34.002  61.288  -14.832 1.00 43.96  ? 82  GLU D CB  1 
ATOM   11281 C CG  . GLU D 1 82  ? 34.625  60.469  -15.955 1.00 58.12  ? 82  GLU D CG  1 
ATOM   11282 C CD  . GLU D 1 82  ? 36.001  60.022  -15.533 1.00 74.83  ? 82  GLU D CD  1 
ATOM   11283 O OE1 . GLU D 1 82  ? 36.077  59.096  -14.689 1.00 81.68  ? 82  GLU D OE1 1 
ATOM   11284 O OE2 . GLU D 1 82  ? 36.974  60.659  -16.002 1.00 78.78  ? 82  GLU D OE2 1 
ATOM   11285 N N   . GLY D 1 83  ? 31.685  61.769  -17.384 1.00 37.73  ? 83  GLY D N   1 
ATOM   11286 C CA  . GLY D 1 83  ? 30.590  61.167  -18.126 1.00 36.34  ? 83  GLY D CA  1 
ATOM   11287 C C   . GLY D 1 83  ? 29.286  61.952  -17.985 1.00 36.19  ? 83  GLY D C   1 
ATOM   11288 O O   . GLY D 1 83  ? 28.253  61.542  -18.494 1.00 38.51  ? 83  GLY D O   1 
ATOM   11289 N N   . GLY D 1 84  ? 29.322  63.084  -17.286 1.00 36.37  ? 84  GLY D N   1 
ATOM   11290 C CA  . GLY D 1 84  ? 28.118  63.851  -17.067 1.00 33.77  ? 84  GLY D CA  1 
ATOM   11291 C C   . GLY D 1 84  ? 28.044  64.948  -18.114 1.00 32.78  ? 84  GLY D C   1 
ATOM   11292 O O   . GLY D 1 84  ? 29.029  65.176  -18.806 1.00 31.31  ? 84  GLY D O   1 
ATOM   11293 N N   . PHE D 1 85  ? 26.878  65.599  -18.196 1.00 31.39  ? 85  PHE D N   1 
ATOM   11294 C CA  . PHE D 1 85  ? 26.689  66.747  -19.066 1.00 31.56  ? 85  PHE D CA  1 
ATOM   11295 C C   . PHE D 1 85  ? 26.504  68.012  -18.228 1.00 27.85  ? 85  PHE D C   1 
ATOM   11296 O O   . PHE D 1 85  ? 26.895  69.086  -18.667 1.00 26.49  ? 85  PHE D O   1 
ATOM   11297 C CB  . PHE D 1 85  ? 25.503  66.596  -20.031 1.00 28.58  ? 85  PHE D CB  1 
ATOM   11298 C CG  . PHE D 1 85  ? 25.344  67.835  -20.907 1.00 29.45  ? 85  PHE D CG  1 
ATOM   11299 C CD1 . PHE D 1 85  ? 26.263  68.124  -21.913 1.00 28.12  ? 85  PHE D CD1 1 
ATOM   11300 C CD2 . PHE D 1 85  ? 24.292  68.725  -20.709 1.00 29.06  ? 85  PHE D CD2 1 
ATOM   11301 C CE1 . PHE D 1 85  ? 26.139  69.277  -22.682 1.00 28.09  ? 85  PHE D CE1 1 
ATOM   11302 C CE2 . PHE D 1 85  ? 24.164  69.860  -21.493 1.00 29.68  ? 85  PHE D CE2 1 
ATOM   11303 C CZ  . PHE D 1 85  ? 25.108  70.151  -22.457 1.00 26.67  ? 85  PHE D CZ  1 
ATOM   11304 N N   . GLU D 1 86  ? 25.881  67.886  -17.054 1.00 25.52  ? 86  GLU D N   1 
ATOM   11305 C CA  . GLU D 1 86  ? 25.440  69.053  -16.292 1.00 25.75  ? 86  GLU D CA  1 
ATOM   11306 C C   . GLU D 1 86  ? 26.612  69.680  -15.516 1.00 25.45  ? 86  GLU D C   1 
ATOM   11307 O O   . GLU D 1 86  ? 27.524  69.014  -14.999 1.00 23.29  ? 86  GLU D O   1 
ATOM   11308 C CB  . GLU D 1 86  ? 24.234  68.733  -15.408 1.00 25.09  ? 86  GLU D CB  1 
ATOM   11309 C CG  . GLU D 1 86  ? 23.021  68.199  -16.186 1.00 26.81  ? 86  GLU D CG  1 
ATOM   11310 C CD  . GLU D 1 86  ? 22.270  69.201  -17.074 1.00 27.02  ? 86  GLU D CD  1 
ATOM   11311 O OE1 . GLU D 1 86  ? 21.404  68.759  -17.885 1.00 26.77  ? 86  GLU D OE1 1 
ATOM   11312 O OE2 . GLU D 1 86  ? 22.549  70.429  -16.980 1.00 27.24  ? 86  GLU D OE2 1 
ATOM   11313 N N   . PRO D 1 87  ? 26.643  71.022  -15.442 1.00 22.64  ? 87  PRO D N   1 
ATOM   11314 C CA  . PRO D 1 87  ? 27.705  71.698  -14.717 1.00 25.44  ? 87  PRO D CA  1 
ATOM   11315 C C   . PRO D 1 87  ? 27.680  71.360  -13.219 1.00 28.85  ? 87  PRO D C   1 
ATOM   11316 O O   . PRO D 1 87  ? 26.614  71.287  -12.592 1.00 25.28  ? 87  PRO D O   1 
ATOM   11317 C CB  . PRO D 1 87  ? 27.392  73.177  -15.002 1.00 24.72  ? 87  PRO D CB  1 
ATOM   11318 C CG  . PRO D 1 87  ? 25.915  73.223  -15.274 1.00 23.75  ? 87  PRO D CG  1 
ATOM   11319 C CD  . PRO D 1 87  ? 25.623  71.928  -15.988 1.00 23.19  ? 87  PRO D CD  1 
ATOM   11320 N N   . LEU D 1 88  ? 28.868  71.126  -12.657 1.00 27.10  ? 88  LEU D N   1 
ATOM   11321 C CA  . LEU D 1 88  ? 28.969  70.900  -11.236 1.00 27.02  ? 88  LEU D CA  1 
ATOM   11322 C C   . LEU D 1 88  ? 28.940  72.253  -10.537 1.00 29.24  ? 88  LEU D C   1 
ATOM   11323 O O   . LEU D 1 88  ? 29.611  73.209  -10.930 1.00 32.00  ? 88  LEU D O   1 
ATOM   11324 C CB  . LEU D 1 88  ? 30.240  70.147  -10.895 1.00 26.88  ? 88  LEU D CB  1 
ATOM   11325 C CG  . LEU D 1 88  ? 30.371  68.761  -11.514 1.00 27.60  ? 88  LEU D CG  1 
ATOM   11326 C CD1 . LEU D 1 88  ? 31.700  68.147  -11.104 1.00 29.95  ? 88  LEU D CD1 1 
ATOM   11327 C CD2 . LEU D 1 88  ? 29.237  67.903  -11.053 1.00 27.42  ? 88  LEU D CD2 1 
ATOM   11328 N N   . PRO D 1 89  ? 28.147  72.365  -9.464  1.00 26.91  ? 89  PRO D N   1 
ATOM   11329 C CA  . PRO D 1 89  ? 28.110  73.591  -8.685  1.00 26.25  ? 89  PRO D CA  1 
ATOM   11330 C C   . PRO D 1 89  ? 29.438  73.974  -8.031  1.00 26.48  ? 89  PRO D C   1 
ATOM   11331 O O   . PRO D 1 89  ? 29.708  75.166  -7.869  1.00 26.50  ? 89  PRO D O   1 
ATOM   11332 C CB  . PRO D 1 89  ? 26.976  73.284  -7.665  1.00 29.30  ? 89  PRO D CB  1 
ATOM   11333 C CG  . PRO D 1 89  ? 26.903  71.781  -7.597  1.00 29.67  ? 89  PRO D CG  1 
ATOM   11334 C CD  . PRO D 1 89  ? 27.197  71.336  -9.012  1.00 29.51  ? 89  PRO D CD  1 
ATOM   11335 N N   . GLU D 1 90  ? 30.275  72.978  -7.692  1.00 25.22  ? 90  GLU D N   1 
ATOM   11336 C CA  . GLU D 1 90  ? 31.639  73.231  -7.213  1.00 23.33  ? 90  GLU D CA  1 
ATOM   11337 C C   . GLU D 1 90  ? 32.351  74.232  -8.124  1.00 24.90  ? 90  GLU D C   1 
ATOM   11338 O O   . GLU D 1 90  ? 32.890  75.226  -7.649  1.00 26.39  ? 90  GLU D O   1 
ATOM   11339 C CB  . GLU D 1 90  ? 32.467  71.958  -7.015  1.00 22.62  ? 90  GLU D CB  1 
ATOM   11340 C CG  . GLU D 1 90  ? 31.868  70.972  -6.007  1.00 22.13  ? 90  GLU D CG  1 
ATOM   11341 C CD  . GLU D 1 90  ? 31.015  69.854  -6.592  1.00 25.02  ? 90  GLU D CD  1 
ATOM   11342 O OE1 . GLU D 1 90  ? 31.359  68.669  -6.345  1.00 26.06  ? 90  GLU D OE1 1 
ATOM   11343 O OE2 . GLU D 1 90  ? 30.007  70.145  -7.303  1.00 25.62  ? 90  GLU D OE2 1 
ATOM   11344 N N   . GLY D 1 91  ? 32.265  74.007  -9.446  1.00 27.62  ? 91  GLY D N   1 
ATOM   11345 C CA  . GLY D 1 91  ? 32.816  74.898  -10.458 1.00 25.51  ? 91  GLY D CA  1 
ATOM   11346 C C   . GLY D 1 91  ? 32.133  76.261  -10.482 1.00 25.67  ? 91  GLY D C   1 
ATOM   11347 O O   . GLY D 1 91  ? 32.786  77.297  -10.686 1.00 23.18  ? 91  GLY D O   1 
ATOM   11348 N N   . LEU D 1 92  ? 30.815  76.261  -10.271 1.00 25.19  ? 92  LEU D N   1 
ATOM   11349 C CA  . LEU D 1 92  ? 30.102  77.526  -10.278 1.00 26.57  ? 92  LEU D CA  1 
ATOM   11350 C C   . LEU D 1 92  ? 30.575  78.362  -9.082  1.00 27.21  ? 92  LEU D C   1 
ATOM   11351 O O   . LEU D 1 92  ? 30.760  79.579  -9.204  1.00 23.28  ? 92  LEU D O   1 
ATOM   11352 C CB  . LEU D 1 92  ? 28.588  77.335  -10.301 1.00 26.13  ? 92  LEU D CB  1 
ATOM   11353 C CG  . LEU D 1 92  ? 27.780  78.628  -10.124 1.00 30.78  ? 92  LEU D CG  1 
ATOM   11354 C CD1 . LEU D 1 92  ? 28.142  79.662  -11.168 1.00 31.21  ? 92  LEU D CD1 1 
ATOM   11355 C CD2 . LEU D 1 92  ? 26.299  78.402  -10.185 1.00 31.60  ? 92  LEU D CD2 1 
ATOM   11356 N N   . TRP D 1 93  ? 30.809  77.688  -7.937  1.00 28.31  ? 93  TRP D N   1 
ATOM   11357 C CA  . TRP D 1 93  ? 31.159  78.375  -6.699  1.00 27.56  ? 93  TRP D CA  1 
ATOM   11358 C C   . TRP D 1 93  ? 32.525  79.031  -6.878  1.00 26.36  ? 93  TRP D C   1 
ATOM   11359 O O   . TRP D 1 93  ? 32.716  80.180  -6.488  1.00 23.40  ? 93  TRP D O   1 
ATOM   11360 C CB  . TRP D 1 93  ? 31.153  77.390  -5.515  1.00 30.12  ? 93  TRP D CB  1 
ATOM   11361 C CG  . TRP D 1 93  ? 31.256  78.028  -4.149  1.00 33.26  ? 93  TRP D CG  1 
ATOM   11362 C CD1 . TRP D 1 93  ? 30.429  78.984  -3.625  1.00 34.29  ? 93  TRP D CD1 1 
ATOM   11363 C CD2 . TRP D 1 93  ? 32.244  77.749  -3.128  1.00 34.56  ? 93  TRP D CD2 1 
ATOM   11364 N NE1 . TRP D 1 93  ? 30.837  79.337  -2.369  1.00 35.38  ? 93  TRP D NE1 1 
ATOM   11365 C CE2 . TRP D 1 93  ? 31.948  78.595  -2.034  1.00 34.14  ? 93  TRP D CE2 1 
ATOM   11366 C CE3 . TRP D 1 93  ? 33.332  76.872  -3.032  1.00 35.10  ? 93  TRP D CE3 1 
ATOM   11367 C CZ2 . TRP D 1 93  ? 32.713  78.596  -0.870  1.00 30.00  ? 93  TRP D CZ2 1 
ATOM   11368 C CZ3 . TRP D 1 93  ? 34.077  76.862  -1.876  1.00 35.31  ? 93  TRP D CZ3 1 
ATOM   11369 C CH2 . TRP D 1 93  ? 33.784  77.735  -0.823  1.00 35.08  ? 93  TRP D CH2 1 
ATOM   11370 N N   . TYR D 1 94  ? 33.456  78.286  -7.511  1.00 28.48  ? 94  TYR D N   1 
ATOM   11371 C CA  . TYR D 1 94  ? 34.786  78.789  -7.841  1.00 30.94  ? 94  TYR D CA  1 
ATOM   11372 C C   . TYR D 1 94  ? 34.638  80.089  -8.634  1.00 34.28  ? 94  TYR D C   1 
ATOM   11373 O O   . TYR D 1 94  ? 35.361  81.056  -8.376  1.00 33.90  ? 94  TYR D O   1 
ATOM   11374 C CB  . TYR D 1 94  ? 35.621  77.776  -8.638  1.00 31.21  ? 94  TYR D CB  1 
ATOM   11375 C CG  . TYR D 1 94  ? 37.046  78.218  -8.963  1.00 31.41  ? 94  TYR D CG  1 
ATOM   11376 C CD1 . TYR D 1 94  ? 37.296  79.181  -9.941  1.00 33.67  ? 94  TYR D CD1 1 
ATOM   11377 C CD2 . TYR D 1 94  ? 38.143  77.674  -8.299  1.00 32.97  ? 94  TYR D CD2 1 
ATOM   11378 C CE1 . TYR D 1 94  ? 38.583  79.620  -10.224 1.00 37.31  ? 94  TYR D CE1 1 
ATOM   11379 C CE2 . TYR D 1 94  ? 39.434  78.113  -8.564  1.00 37.75  ? 94  TYR D CE2 1 
ATOM   11380 C CZ  . TYR D 1 94  ? 39.662  79.087  -9.533  1.00 39.32  ? 94  TYR D CZ  1 
ATOM   11381 O OH  . TYR D 1 94  ? 40.938  79.501  -9.841  1.00 36.18  ? 94  TYR D OH  1 
ATOM   11382 N N   . LEU D 1 95  ? 33.708  80.089  -9.604  1.00 29.59  ? 95  LEU D N   1 
ATOM   11383 C CA  . LEU D 1 95  ? 33.581  81.211  -10.518 1.00 30.26  ? 95  LEU D CA  1 
ATOM   11384 C C   . LEU D 1 95  ? 32.957  82.393  -9.785  1.00 28.30  ? 95  LEU D C   1 
ATOM   11385 O O   . LEU D 1 95  ? 33.385  83.518  -9.972  1.00 31.55  ? 95  LEU D O   1 
ATOM   11386 C CB  . LEU D 1 95  ? 32.815  80.827  -11.795 1.00 28.01  ? 95  LEU D CB  1 
ATOM   11387 C CG  . LEU D 1 95  ? 32.076  81.952  -12.536 1.00 24.86  ? 95  LEU D CG  1 
ATOM   11388 C CD1 . LEU D 1 95  ? 33.022  82.928  -13.173 1.00 22.51  ? 95  LEU D CD1 1 
ATOM   11389 C CD2 . LEU D 1 95  ? 31.122  81.365  -13.571 1.00 26.35  ? 95  LEU D CD2 1 
ATOM   11390 N N   . LEU D 1 96  ? 31.942  82.133  -8.965  1.00 28.94  ? 96  LEU D N   1 
ATOM   11391 C CA  . LEU D 1 96  ? 31.299  83.181  -8.184  1.00 28.76  ? 96  LEU D CA  1 
ATOM   11392 C C   . LEU D 1 96  ? 32.335  83.897  -7.344  1.00 26.58  ? 96  LEU D C   1 
ATOM   11393 O O   . LEU D 1 96  ? 32.229  85.106  -7.198  1.00 29.09  ? 96  LEU D O   1 
ATOM   11394 C CB  . LEU D 1 96  ? 30.189  82.678  -7.260  1.00 29.76  ? 96  LEU D CB  1 
ATOM   11395 C CG  . LEU D 1 96  ? 28.949  82.065  -7.912  1.00 32.36  ? 96  LEU D CG  1 
ATOM   11396 C CD1 . LEU D 1 96  ? 27.901  81.615  -6.899  1.00 33.02  ? 96  LEU D CD1 1 
ATOM   11397 C CD2 . LEU D 1 96  ? 28.353  83.080  -8.873  1.00 34.94  ? 96  LEU D CD2 1 
ATOM   11398 N N   . LEU D 1 97  ? 33.285  83.151  -6.758  1.00 26.39  ? 97  LEU D N   1 
ATOM   11399 C CA  . LEU D 1 97  ? 34.264  83.762  -5.856  1.00 28.58  ? 97  LEU D CA  1 
ATOM   11400 C C   . LEU D 1 97  ? 35.340  84.568  -6.605  1.00 30.06  ? 97  LEU D C   1 
ATOM   11401 O O   . LEU D 1 97  ? 35.627  85.703  -6.210  1.00 27.33  ? 97  LEU D O   1 
ATOM   11402 C CB  . LEU D 1 97  ? 34.903  82.709  -4.957  1.00 27.06  ? 97  LEU D CB  1 
ATOM   11403 C CG  . LEU D 1 97  ? 34.105  82.342  -3.708  1.00 26.01  ? 97  LEU D CG  1 
ATOM   11404 C CD1 . LEU D 1 97  ? 34.598  81.046  -3.101  1.00 25.69  ? 97  LEU D CD1 1 
ATOM   11405 C CD2 . LEU D 1 97  ? 34.197  83.481  -2.735  1.00 26.14  ? 97  LEU D CD2 1 
ATOM   11406 N N   . THR D 1 98  ? 35.950  83.976  -7.656  1.00 28.82  ? 98  THR D N   1 
ATOM   11407 C CA  . THR D 1 98  ? 37.113  84.552  -8.330  1.00 28.91  ? 98  THR D CA  1 
ATOM   11408 C C   . THR D 1 98  ? 36.716  85.439  -9.513  1.00 32.26  ? 98  THR D C   1 
ATOM   11409 O O   . THR D 1 98  ? 37.432  86.379  -9.855  1.00 34.33  ? 98  THR D O   1 
ATOM   11410 C CB  . THR D 1 98  ? 38.077  83.462  -8.792  1.00 28.27  ? 98  THR D CB  1 
ATOM   11411 O OG1 . THR D 1 98  ? 37.453  82.665  -9.789  1.00 28.22  ? 98  THR D OG1 1 
ATOM   11412 C CG2 . THR D 1 98  ? 38.550  82.577  -7.651  1.00 30.15  ? 98  THR D CG2 1 
ATOM   11413 N N   . GLY D 1 99  ? 35.586  85.139  -10.155 1.00 31.14  ? 99  GLY D N   1 
ATOM   11414 C CA  . GLY D 1 99  ? 35.249  85.787  -11.409 1.00 29.29  ? 99  GLY D CA  1 
ATOM   11415 C C   . GLY D 1 99  ? 35.996  85.140  -12.566 1.00 27.36  ? 99  GLY D C   1 
ATOM   11416 O O   . GLY D 1 99  ? 35.971  85.672  -13.665 1.00 30.66  ? 99  GLY D O   1 
ATOM   11417 N N   . GLU D 1 100 ? 36.606  83.977  -12.310 1.00 26.90  ? 100 GLU D N   1 
ATOM   11418 C CA  . GLU D 1 100 ? 37.408  83.256  -13.284 1.00 27.20  ? 100 GLU D CA  1 
ATOM   11419 C C   . GLU D 1 100 ? 36.830  81.857  -13.515 1.00 25.65  ? 100 GLU D C   1 
ATOM   11420 O O   . GLU D 1 100 ? 36.343  81.227  -12.593 1.00 25.14  ? 100 GLU D O   1 
ATOM   11421 C CB  . GLU D 1 100 ? 38.854  83.182  -12.779 1.00 29.21  ? 100 GLU D CB  1 
ATOM   11422 C CG  . GLU D 1 100 ? 39.524  84.550  -12.733 1.00 30.60  ? 100 GLU D CG  1 
ATOM   11423 C CD  . GLU D 1 100 ? 40.915  84.588  -12.116 1.00 33.53  ? 100 GLU D CD  1 
ATOM   11424 O OE1 . GLU D 1 100 ? 41.464  85.721  -12.221 1.00 36.56  ? 100 GLU D OE1 1 
ATOM   11425 O OE2 . GLU D 1 100 ? 41.414  83.589  -11.521 1.00 27.56  ? 100 GLU D OE2 1 
ATOM   11426 N N   . LEU D 1 101 ? 36.942  81.351  -14.746 1.00 24.29  ? 101 LEU D N   1 
ATOM   11427 C CA  . LEU D 1 101 ? 36.410  80.054  -15.105 1.00 24.84  ? 101 LEU D CA  1 
ATOM   11428 C C   . LEU D 1 101 ? 37.330  78.971  -14.570 1.00 26.10  ? 101 LEU D C   1 
ATOM   11429 O O   . LEU D 1 101 ? 38.512  78.999  -14.871 1.00 28.91  ? 101 LEU D O   1 
ATOM   11430 C CB  . LEU D 1 101 ? 36.305  79.957  -16.621 1.00 25.68  ? 101 LEU D CB  1 
ATOM   11431 C CG  . LEU D 1 101 ? 35.275  80.890  -17.254 1.00 28.38  ? 101 LEU D CG  1 
ATOM   11432 C CD1 . LEU D 1 101 ? 35.444  80.835  -18.748 1.00 29.29  ? 101 LEU D CD1 1 
ATOM   11433 C CD2 . LEU D 1 101 ? 33.842  80.541  -16.843 1.00 29.26  ? 101 LEU D CD2 1 
ATOM   11434 N N   . PRO D 1 102 ? 36.823  77.974  -13.809 1.00 26.38  ? 102 PRO D N   1 
ATOM   11435 C CA  . PRO D 1 102 ? 37.679  76.948  -13.211 1.00 28.52  ? 102 PRO D CA  1 
ATOM   11436 C C   . PRO D 1 102 ? 38.178  75.935  -14.223 1.00 30.44  ? 102 PRO D C   1 
ATOM   11437 O O   . PRO D 1 102 ? 37.415  75.570  -15.120 1.00 31.56  ? 102 PRO D O   1 
ATOM   11438 C CB  . PRO D 1 102 ? 36.752  76.276  -12.189 1.00 24.98  ? 102 PRO D CB  1 
ATOM   11439 C CG  . PRO D 1 102 ? 35.414  76.412  -12.802 1.00 23.75  ? 102 PRO D CG  1 
ATOM   11440 C CD  . PRO D 1 102 ? 35.412  77.785  -13.460 1.00 23.69  ? 102 PRO D CD  1 
ATOM   11441 N N   . THR D 1 103 ? 39.413  75.456  -14.026 1.00 29.02  ? 103 THR D N   1 
ATOM   11442 C CA  . THR D 1 103 ? 39.847  74.252  -14.722 1.00 34.32  ? 103 THR D CA  1 
ATOM   11443 C C   . THR D 1 103 ? 39.224  73.042  -14.029 1.00 38.85  ? 103 THR D C   1 
ATOM   11444 O O   . THR D 1 103 ? 38.822  73.113  -12.862 1.00 36.99  ? 103 THR D O   1 
ATOM   11445 C CB  . THR D 1 103 ? 41.370  74.082  -14.772 1.00 33.89  ? 103 THR D CB  1 
ATOM   11446 O OG1 . THR D 1 103 ? 41.809  73.594  -13.501 1.00 32.80  ? 103 THR D OG1 1 
ATOM   11447 C CG2 . THR D 1 103 ? 42.082  75.365  -15.170 1.00 32.91  ? 103 THR D CG2 1 
ATOM   11448 N N   . GLU D 1 104 ? 39.180  71.944  -14.789 1.00 40.18  ? 104 GLU D N   1 
ATOM   11449 C CA  . GLU D 1 104 ? 38.897  70.612  -14.291 1.00 43.72  ? 104 GLU D CA  1 
ATOM   11450 C C   . GLU D 1 104 ? 39.522  70.386  -12.913 1.00 39.98  ? 104 GLU D C   1 
ATOM   11451 O O   . GLU D 1 104 ? 38.864  69.883  -12.005 1.00 38.63  ? 104 GLU D O   1 
ATOM   11452 C CB  . GLU D 1 104 ? 39.480  69.644  -15.320 1.00 49.12  ? 104 GLU D CB  1 
ATOM   11453 C CG  . GLU D 1 104 ? 38.619  69.468  -16.570 1.00 51.89  ? 104 GLU D CG  1 
ATOM   11454 C CD  . GLU D 1 104 ? 37.407  68.570  -16.357 1.00 52.12  ? 104 GLU D CD  1 
ATOM   11455 O OE1 . GLU D 1 104 ? 36.339  68.906  -16.904 1.00 52.63  ? 104 GLU D OE1 1 
ATOM   11456 O OE2 . GLU D 1 104 ? 37.518  67.549  -15.641 1.00 53.69  ? 104 GLU D OE2 1 
ATOM   11457 N N   . GLU D 1 105 ? 40.803  70.736  -12.772 1.00 39.47  ? 105 GLU D N   1 
ATOM   11458 C CA  . GLU D 1 105 ? 41.558  70.394  -11.578 1.00 42.51  ? 105 GLU D CA  1 
ATOM   11459 C C   . GLU D 1 105 ? 41.102  71.298  -10.428 1.00 38.34  ? 105 GLU D C   1 
ATOM   11460 O O   . GLU D 1 105 ? 40.993  70.829  -9.295  1.00 34.91  ? 105 GLU D O   1 
ATOM   11461 C CB  . GLU D 1 105 ? 43.076  70.372  -11.826 1.00 45.27  ? 105 GLU D CB  1 
ATOM   11462 C CG  . GLU D 1 105 ? 43.914  69.978  -10.606 1.00 54.80  ? 105 GLU D CG  1 
ATOM   11463 C CD  . GLU D 1 105 ? 43.724  68.579  -9.975  1.00 63.14  ? 105 GLU D CD  1 
ATOM   11464 O OE1 . GLU D 1 105 ? 43.413  67.592  -10.719 1.00 53.91  ? 105 GLU D OE1 1 
ATOM   11465 O OE2 . GLU D 1 105 ? 43.958  68.460  -8.725  1.00 57.62  ? 105 GLU D OE2 1 
ATOM   11466 N N   . ASP D 1 106 ? 40.804  72.572  -10.717 1.00 33.56  ? 106 ASP D N   1 
ATOM   11467 C CA  . ASP D 1 106 ? 40.270  73.463  -9.695  1.00 33.74  ? 106 ASP D CA  1 
ATOM   11468 C C   . ASP D 1 106 ? 38.952  72.916  -9.113  1.00 34.59  ? 106 ASP D C   1 
ATOM   11469 O O   . ASP D 1 106 ? 38.671  73.082  -7.919  1.00 33.26  ? 106 ASP D O   1 
ATOM   11470 C CB  . ASP D 1 106 ? 40.093  74.868  -10.246 1.00 34.18  ? 106 ASP D CB  1 
ATOM   11471 C CG  . ASP D 1 106 ? 41.300  75.473  -10.943 1.00 35.95  ? 106 ASP D CG  1 
ATOM   11472 O OD1 . ASP D 1 106 ? 42.441  75.042  -10.652 1.00 37.86  ? 106 ASP D OD1 1 
ATOM   11473 O OD2 . ASP D 1 106 ? 41.071  76.332  -11.821 1.00 37.09  ? 106 ASP D OD2 1 
ATOM   11474 N N   . VAL D 1 107 ? 38.116  72.297  -9.959  1.00 29.18  ? 107 VAL D N   1 
ATOM   11475 C CA  . VAL D 1 107 ? 36.847  71.765  -9.506  1.00 30.91  ? 107 VAL D CA  1 
ATOM   11476 C C   . VAL D 1 107 ? 37.066  70.487  -8.680  1.00 33.85  ? 107 VAL D C   1 
ATOM   11477 O O   . VAL D 1 107 ? 36.349  70.268  -7.719  1.00 31.45  ? 107 VAL D O   1 
ATOM   11478 C CB  . VAL D 1 107 ? 35.888  71.570  -10.698 1.00 29.63  ? 107 VAL D CB  1 
ATOM   11479 C CG1 . VAL D 1 107 ? 34.736  70.616  -10.413 1.00 29.75  ? 107 VAL D CG1 1 
ATOM   11480 C CG2 . VAL D 1 107 ? 35.334  72.895  -11.194 1.00 27.82  ? 107 VAL D CG2 1 
ATOM   11481 N N   . LYS D 1 108 ? 38.049  69.638  -9.011  1.00 36.96  ? 108 LYS D N   1 
ATOM   11482 C CA  . LYS D 1 108 ? 38.277  68.423  -8.234  1.00 36.92  ? 108 LYS D CA  1 
ATOM   11483 C C   . LYS D 1 108 ? 38.778  68.777  -6.829  1.00 33.59  ? 108 LYS D C   1 
ATOM   11484 O O   . LYS D 1 108 ? 38.482  68.073  -5.864  1.00 28.24  ? 108 LYS D O   1 
ATOM   11485 C CB  . LYS D 1 108 ? 39.248  67.457  -8.926  1.00 41.21  ? 108 LYS D CB  1 
ATOM   11486 C CG  . LYS D 1 108 ? 38.753  66.819  -10.224 1.00 47.65  ? 108 LYS D CG  1 
ATOM   11487 C CD  . LYS D 1 108 ? 39.875  66.006  -10.862 1.00 61.65  ? 108 LYS D CD  1 
ATOM   11488 C CE  . LYS D 1 108 ? 39.736  65.671  -12.311 1.00 65.62  ? 108 LYS D CE  1 
ATOM   11489 N NZ  . LYS D 1 108 ? 38.634  64.730  -12.507 1.00 71.25  ? 108 LYS D NZ  1 
ATOM   11490 N N   . GLU D 1 109 ? 39.540  69.874  -6.720  1.00 31.22  ? 109 GLU D N   1 
ATOM   11491 C CA  . GLU D 1 109 ? 40.054  70.339  -5.438  1.00 31.43  ? 109 GLU D CA  1 
ATOM   11492 C C   . GLU D 1 109 ? 38.865  70.616  -4.509  1.00 30.74  ? 109 GLU D C   1 
ATOM   11493 O O   . GLU D 1 109 ? 38.768  70.106  -3.389  1.00 31.16  ? 109 GLU D O   1 
ATOM   11494 C CB  . GLU D 1 109 ? 40.998  71.545  -5.599  1.00 31.02  ? 109 GLU D CB  1 
ATOM   11495 C CG  . GLU D 1 109 ? 42.409  71.213  -6.112  1.00 30.99  ? 109 GLU D CG  1 
ATOM   11496 C CD  . GLU D 1 109 ? 43.407  72.378  -6.239  1.00 34.33  ? 109 GLU D CD  1 
ATOM   11497 O OE1 . GLU D 1 109 ? 44.588  72.177  -6.629  1.00 38.92  ? 109 GLU D OE1 1 
ATOM   11498 O OE2 . GLU D 1 109 ? 43.027  73.524  -5.930  1.00 34.27  ? 109 GLU D OE2 1 
ATOM   11499 N N   . ILE D 1 110 ? 37.925  71.401  -5.011  1.00 29.01  ? 110 ILE D N   1 
ATOM   11500 C CA  . ILE D 1 110 ? 36.778  71.798  -4.228  1.00 29.08  ? 110 ILE D CA  1 
ATOM   11501 C C   . ILE D 1 110 ? 35.929  70.574  -3.877  1.00 29.04  ? 110 ILE D C   1 
ATOM   11502 O O   . ILE D 1 110 ? 35.567  70.419  -2.713  1.00 28.22  ? 110 ILE D O   1 
ATOM   11503 C CB  . ILE D 1 110 ? 36.011  72.898  -4.967  1.00 27.00  ? 110 ILE D CB  1 
ATOM   11504 C CG1 . ILE D 1 110 ? 36.817  74.180  -4.967  1.00 25.25  ? 110 ILE D CG1 1 
ATOM   11505 C CG2 . ILE D 1 110 ? 34.620  73.092  -4.358  1.00 28.99  ? 110 ILE D CG2 1 
ATOM   11506 C CD1 . ILE D 1 110 ? 36.220  75.241  -5.876  1.00 28.48  ? 110 ILE D CD1 1 
ATOM   11507 N N   . SER D 1 111 ? 35.698  69.672  -4.846  1.00 26.65  ? 111 SER D N   1 
ATOM   11508 C CA  . SER D 1 111 ? 34.949  68.455  -4.590  1.00 26.43  ? 111 SER D CA  1 
ATOM   11509 C C   . SER D 1 111 ? 35.596  67.646  -3.472  1.00 29.01  ? 111 SER D C   1 
ATOM   11510 O O   . SER D 1 111 ? 34.889  67.076  -2.649  1.00 31.23  ? 111 SER D O   1 
ATOM   11511 C CB  . SER D 1 111 ? 34.763  67.619  -5.829  1.00 25.62  ? 111 SER D CB  1 
ATOM   11512 O OG  . SER D 1 111 ? 33.702  68.152  -6.624  1.00 28.45  ? 111 SER D OG  1 
ATOM   11513 N N   . ALA D 1 112 ? 36.931  67.577  -3.488  1.00 29.51  ? 112 ALA D N   1 
ATOM   11514 C CA  . ALA D 1 112 ? 37.704  66.791  -2.551  1.00 31.17  ? 112 ALA D CA  1 
ATOM   11515 C C   . ALA D 1 112 ? 37.671  67.456  -1.173  1.00 32.76  ? 112 ALA D C   1 
ATOM   11516 O O   . ALA D 1 112 ? 37.699  66.786  -0.152  1.00 33.89  ? 112 ALA D O   1 
ATOM   11517 C CB  . ALA D 1 112 ? 39.132  66.657  -3.077  1.00 31.55  ? 112 ALA D CB  1 
ATOM   11518 N N   . GLU D 1 113 ? 37.624  68.787  -1.159  1.00 34.05  ? 113 GLU D N   1 
ATOM   11519 C CA  . GLU D 1 113 ? 37.532  69.545  0.073   1.00 34.16  ? 113 GLU D CA  1 
ATOM   11520 C C   . GLU D 1 113 ? 36.132  69.355  0.680   1.00 35.32  ? 113 GLU D C   1 
ATOM   11521 O O   . GLU D 1 113 ? 35.980  69.221  1.894   1.00 39.62  ? 113 GLU D O   1 
ATOM   11522 C CB  . GLU D 1 113 ? 37.959  70.965  -0.303  1.00 36.25  ? 113 GLU D CB  1 
ATOM   11523 C CG  . GLU D 1 113 ? 38.605  71.779  0.811   1.00 39.17  ? 113 GLU D CG  1 
ATOM   11524 C CD  . GLU D 1 113 ? 39.955  71.335  1.361   1.00 41.46  ? 113 GLU D CD  1 
ATOM   11525 O OE1 . GLU D 1 113 ? 39.930  70.874  2.519   1.00 49.16  ? 113 GLU D OE1 1 
ATOM   11526 O OE2 . GLU D 1 113 ? 41.018  71.486  0.720   1.00 38.26  ? 113 GLU D OE2 1 
ATOM   11527 N N   . PHE D 1 114 ? 35.083  69.324  -0.139  1.00 30.78  ? 114 PHE D N   1 
ATOM   11528 C CA  . PHE D 1 114 ? 33.754  69.107  0.402   1.00 28.83  ? 114 PHE D CA  1 
ATOM   11529 C C   . PHE D 1 114 ? 33.663  67.685  0.940   1.00 31.34  ? 114 PHE D C   1 
ATOM   11530 O O   . PHE D 1 114 ? 33.262  67.466  2.081   1.00 33.04  ? 114 PHE D O   1 
ATOM   11531 C CB  . PHE D 1 114 ? 32.705  69.395  -0.662  1.00 28.14  ? 114 PHE D CB  1 
ATOM   11532 C CG  . PHE D 1 114 ? 32.476  70.865  -1.005  1.00 27.68  ? 114 PHE D CG  1 
ATOM   11533 C CD1 . PHE D 1 114 ? 32.953  71.887  -0.196  1.00 27.44  ? 114 PHE D CD1 1 
ATOM   11534 C CD2 . PHE D 1 114 ? 31.722  71.212  -2.116  1.00 26.86  ? 114 PHE D CD2 1 
ATOM   11535 C CE1 . PHE D 1 114 ? 32.689  73.212  -0.496  1.00 29.61  ? 114 PHE D CE1 1 
ATOM   11536 C CE2 . PHE D 1 114 ? 31.468  72.539  -2.418  1.00 30.55  ? 114 PHE D CE2 1 
ATOM   11537 C CZ  . PHE D 1 114 ? 31.952  73.541  -1.611  1.00 30.63  ? 114 PHE D CZ  1 
ATOM   11538 N N   . THR D 1 115 ? 34.118  66.727  0.144   1.00 29.96  ? 115 THR D N   1 
ATOM   11539 C CA  . THR D 1 115 ? 34.122  65.338  0.566   1.00 34.05  ? 115 THR D CA  1 
ATOM   11540 C C   . THR D 1 115 ? 34.884  65.159  1.892   1.00 36.95  ? 115 THR D C   1 
ATOM   11541 O O   . THR D 1 115 ? 34.469  64.367  2.736   1.00 43.17  ? 115 THR D O   1 
ATOM   11542 C CB  . THR D 1 115 ? 34.682  64.483  -0.580  1.00 34.20  ? 115 THR D CB  1 
ATOM   11543 O OG1 . THR D 1 115 ? 33.617  64.206  -1.476  1.00 30.24  ? 115 THR D OG1 1 
ATOM   11544 C CG2 . THR D 1 115 ? 35.149  63.105  -0.156  1.00 38.59  ? 115 THR D CG2 1 
ATOM   11545 N N   . LYS D 1 116 ? 36.020  65.843  2.078   1.00 35.52  ? 116 LYS D N   1 
ATOM   11546 C CA  . LYS D 1 116 ? 36.832  65.617  3.259   1.00 34.21  ? 116 LYS D CA  1 
ATOM   11547 C C   . LYS D 1 116 ? 36.071  66.141  4.472   1.00 32.52  ? 116 LYS D C   1 
ATOM   11548 O O   . LYS D 1 116 ? 35.851  65.413  5.430   1.00 28.27  ? 116 LYS D O   1 
ATOM   11549 C CB  . LYS D 1 116 ? 38.253  66.170  3.059   1.00 39.73  ? 116 LYS D CB  1 
ATOM   11550 C CG  . LYS D 1 116 ? 39.035  66.538  4.329   1.00 48.87  ? 116 LYS D CG  1 
ATOM   11551 C CD  . LYS D 1 116 ? 40.545  66.286  4.356   1.00 59.80  ? 116 LYS D CD  1 
ATOM   11552 C CE  . LYS D 1 116 ? 41.364  67.091  3.373   1.00 72.20  ? 116 LYS D CE  1 
ATOM   11553 N NZ  . LYS D 1 116 ? 41.456  68.543  3.619   1.00 69.21  ? 116 LYS D NZ  1 
ATOM   11554 N N   . ARG D 1 117 ? 35.636  67.402  4.382   1.00 34.10  ? 117 ARG D N   1 
ATOM   11555 C CA  . ARG D 1 117 ? 34.956  68.125  5.446   1.00 30.46  ? 117 ARG D CA  1 
ATOM   11556 C C   . ARG D 1 117 ? 33.546  67.584  5.724   1.00 31.61  ? 117 ARG D C   1 
ATOM   11557 O O   . ARG D 1 117 ? 32.928  67.925  6.731   1.00 35.53  ? 117 ARG D O   1 
ATOM   11558 C CB  . ARG D 1 117 ? 34.948  69.607  5.046   1.00 28.90  ? 117 ARG D CB  1 
ATOM   11559 C CG  . ARG D 1 117 ? 36.349  70.188  4.942   1.00 29.53  ? 117 ARG D CG  1 
ATOM   11560 C CD  . ARG D 1 117 ? 36.423  71.597  4.339   1.00 32.35  ? 117 ARG D CD  1 
ATOM   11561 N NE  . ARG D 1 117 ? 37.830  71.991  4.167   1.00 31.59  ? 117 ARG D NE  1 
ATOM   11562 C CZ  . ARG D 1 117 ? 38.500  72.908  4.853   1.00 35.43  ? 117 ARG D CZ  1 
ATOM   11563 N NH1 . ARG D 1 117 ? 37.974  73.586  5.859   1.00 39.13  ? 117 ARG D NH1 1 
ATOM   11564 N NH2 . ARG D 1 117 ? 39.748  73.139  4.555   1.00 37.27  ? 117 ARG D NH2 1 
ATOM   11565 N N   . MET D 1 118 ? 33.030  66.718  4.854   1.00 33.57  ? 118 MET D N   1 
ATOM   11566 C CA  . MET D 1 118 ? 31.720  66.119  5.043   1.00 34.74  ? 118 MET D CA  1 
ATOM   11567 C C   . MET D 1 118 ? 31.741  65.202  6.265   1.00 37.42  ? 118 MET D C   1 
ATOM   11568 O O   . MET D 1 118 ? 30.719  65.013  6.932   1.00 42.54  ? 118 MET D O   1 
ATOM   11569 C CB  . MET D 1 118 ? 31.350  65.283  3.818   1.00 36.05  ? 118 MET D CB  1 
ATOM   11570 C CG  . MET D 1 118 ? 30.091  65.722  3.158   1.00 41.19  ? 118 MET D CG  1 
ATOM   11571 S SD  . MET D 1 118 ? 29.768  64.697  1.714   1.00 40.33  ? 118 MET D SD  1 
ATOM   11572 C CE  . MET D 1 118 ? 29.348  66.144  0.725   1.00 44.58  ? 118 MET D CE  1 
ATOM   11573 N N   . GLN D 1 119 ? 32.911  64.608  6.525   1.00 33.95  ? 119 GLN D N   1 
ATOM   11574 C CA  . GLN D 1 119 ? 33.104  63.715  7.651   1.00 35.32  ? 119 GLN D CA  1 
ATOM   11575 C C   . GLN D 1 119 ? 33.189  64.487  8.971   1.00 35.02  ? 119 GLN D C   1 
ATOM   11576 O O   . GLN D 1 119 ? 33.344  63.861  10.011  1.00 33.24  ? 119 GLN D O   1 
ATOM   11577 C CB  . GLN D 1 119 ? 34.426  62.992  7.414   1.00 40.37  ? 119 GLN D CB  1 
ATOM   11578 C CG  . GLN D 1 119 ? 34.455  62.081  6.192   1.00 46.30  ? 119 GLN D CG  1 
ATOM   11579 C CD  . GLN D 1 119 ? 33.478  60.933  6.325   1.00 57.54  ? 119 GLN D CD  1 
ATOM   11580 O OE1 . GLN D 1 119 ? 33.423  60.261  7.363   1.00 68.28  ? 119 GLN D OE1 1 
ATOM   11581 N NE2 . GLN D 1 119 ? 32.656  60.730  5.305   1.00 57.58  ? 119 GLN D NE2 1 
ATOM   11582 N N   . ASN D 1 120 ? 33.098  65.832  8.948   1.00 32.02  ? 120 ASN D N   1 
ATOM   11583 C CA  . ASN D 1 120 ? 33.375  66.632  10.129  1.00 32.92  ? 120 ASN D CA  1 
ATOM   11584 C C   . ASN D 1 120 ? 32.144  67.307  10.719  1.00 30.58  ? 120 ASN D C   1 
ATOM   11585 O O   . ASN D 1 120 ? 32.296  68.278  11.468  1.00 27.61  ? 120 ASN D O   1 
ATOM   11586 C CB  . ASN D 1 120 ? 34.390  67.720  9.833   1.00 36.72  ? 120 ASN D CB  1 
ATOM   11587 C CG  . ASN D 1 120 ? 35.740  67.133  9.512   1.00 40.15  ? 120 ASN D CG  1 
ATOM   11588 O OD1 . ASN D 1 120 ? 36.570  67.841  8.932   1.00 41.85  ? 120 ASN D OD1 1 
ATOM   11589 N ND2 . ASN D 1 120 ? 35.958  65.857  9.822   1.00 38.74  ? 120 ASN D ND2 1 
ATOM   11590 N N   . VAL D 1 121 ? 30.953  66.759  10.440  1.00 25.41  ? 121 VAL D N   1 
ATOM   11591 C CA  . VAL D 1 121 ? 29.761  67.275  11.078  1.00 26.54  ? 121 VAL D CA  1 
ATOM   11592 C C   . VAL D 1 121 ? 29.754  66.751  12.510  1.00 24.93  ? 121 VAL D C   1 
ATOM   11593 O O   . VAL D 1 121 ? 29.778  65.537  12.726  1.00 25.98  ? 121 VAL D O   1 
ATOM   11594 C CB  . VAL D 1 121 ? 28.445  66.897  10.385  1.00 29.39  ? 121 VAL D CB  1 
ATOM   11595 C CG1 . VAL D 1 121 ? 27.276  67.600  11.048  1.00 31.20  ? 121 VAL D CG1 1 
ATOM   11596 C CG2 . VAL D 1 121 ? 28.469  67.205  8.891   1.00 33.17  ? 121 VAL D CG2 1 
ATOM   11597 N N   . PRO D 1 122 ? 29.710  67.643  13.514  1.00 21.11  ? 122 PRO D N   1 
ATOM   11598 C CA  . PRO D 1 122 ? 29.696  67.230  14.922  1.00 22.60  ? 122 PRO D CA  1 
ATOM   11599 C C   . PRO D 1 122 ? 28.539  66.307  15.296  1.00 24.78  ? 122 PRO D C   1 
ATOM   11600 O O   . PRO D 1 122 ? 27.419  66.493  14.807  1.00 25.36  ? 122 PRO D O   1 
ATOM   11601 C CB  . PRO D 1 122 ? 29.600  68.552  15.706  1.00 22.29  ? 122 PRO D CB  1 
ATOM   11602 C CG  . PRO D 1 122 ? 29.978  69.636  14.711  1.00 22.16  ? 122 PRO D CG  1 
ATOM   11603 C CD  . PRO D 1 122 ? 29.675  69.096  13.330  1.00 22.02  ? 122 PRO D CD  1 
ATOM   11604 N N   . GLN D 1 123 ? 28.810  65.341  16.189  1.00 26.92  ? 123 GLN D N   1 
ATOM   11605 C CA  . GLN D 1 123 ? 27.773  64.456  16.698  1.00 28.12  ? 123 GLN D CA  1 
ATOM   11606 C C   . GLN D 1 123 ? 26.618  65.244  17.332  1.00 28.26  ? 123 GLN D C   1 
ATOM   11607 O O   . GLN D 1 123 ? 25.478  64.783  17.263  1.00 26.74  ? 123 GLN D O   1 
ATOM   11608 C CB  . GLN D 1 123 ? 28.280  63.438  17.712  1.00 32.45  ? 123 GLN D CB  1 
ATOM   11609 C CG  . GLN D 1 123 ? 27.476  62.138  17.685  1.00 42.35  ? 123 GLN D CG  1 
ATOM   11610 C CD  . GLN D 1 123 ? 27.846  61.175  18.799  1.00 50.57  ? 123 GLN D CD  1 
ATOM   11611 O OE1 . GLN D 1 123 ? 27.024  60.853  19.666  1.00 57.85  ? 123 GLN D OE1 1 
ATOM   11612 N NE2 . GLN D 1 123 ? 29.088  60.706  18.804  1.00 50.27  ? 123 GLN D NE2 1 
ATOM   11613 N N   . TYR D 1 124 ? 26.894  66.418  17.941  1.00 26.18  ? 124 TYR D N   1 
ATOM   11614 C CA  . TYR D 1 124 ? 25.883  67.110  18.727  1.00 25.94  ? 124 TYR D CA  1 
ATOM   11615 C C   . TYR D 1 124 ? 24.831  67.742  17.793  1.00 26.73  ? 124 TYR D C   1 
ATOM   11616 O O   . TYR D 1 124 ? 23.670  67.952  18.179  1.00 24.46  ? 124 TYR D O   1 
ATOM   11617 C CB  . TYR D 1 124 ? 26.574  68.052  19.720  1.00 24.70  ? 124 TYR D CB  1 
ATOM   11618 C CG  . TYR D 1 124 ? 27.260  69.237  19.070  1.00 25.15  ? 124 TYR D CG  1 
ATOM   11619 C CD1 . TYR D 1 124 ? 26.515  70.257  18.485  1.00 25.68  ? 124 TYR D CD1 1 
ATOM   11620 C CD2 . TYR D 1 124 ? 28.649  69.329  19.016  1.00 25.00  ? 124 TYR D CD2 1 
ATOM   11621 C CE1 . TYR D 1 124 ? 27.130  71.324  17.842  1.00 27.94  ? 124 TYR D CE1 1 
ATOM   11622 C CE2 . TYR D 1 124 ? 29.275  70.404  18.404  1.00 24.32  ? 124 TYR D CE2 1 
ATOM   11623 C CZ  . TYR D 1 124 ? 28.517  71.396  17.811  1.00 25.94  ? 124 TYR D CZ  1 
ATOM   11624 O OH  . TYR D 1 124 ? 29.113  72.428  17.175  1.00 27.13  ? 124 TYR D OH  1 
ATOM   11625 N N   . VAL D 1 125 ? 25.219  67.990  16.538  1.00 24.59  ? 125 VAL D N   1 
ATOM   11626 C CA  . VAL D 1 125 ? 24.292  68.481  15.540  1.00 22.40  ? 125 VAL D CA  1 
ATOM   11627 C C   . VAL D 1 125 ? 23.214  67.433  15.320  1.00 20.91  ? 125 VAL D C   1 
ATOM   11628 O O   . VAL D 1 125 ? 22.051  67.751  15.182  1.00 20.33  ? 125 VAL D O   1 
ATOM   11629 C CB  . VAL D 1 125 ? 25.038  68.813  14.244  1.00 23.63  ? 125 VAL D CB  1 
ATOM   11630 C CG1 . VAL D 1 125 ? 24.087  69.041  13.067  1.00 27.92  ? 125 VAL D CG1 1 
ATOM   11631 C CG2 . VAL D 1 125 ? 25.960  70.013  14.417  1.00 23.40  ? 125 VAL D CG2 1 
ATOM   11632 N N   . PHE D 1 126 ? 23.584  66.166  15.267  1.00 21.87  ? 126 PHE D N   1 
ATOM   11633 C CA  . PHE D 1 126 ? 22.566  65.150  15.118  1.00 22.08  ? 126 PHE D CA  1 
ATOM   11634 C C   . PHE D 1 126 ? 21.747  65.123  16.392  1.00 24.66  ? 126 PHE D C   1 
ATOM   11635 O O   . PHE D 1 126 ? 20.526  64.979  16.327  1.00 24.65  ? 126 PHE D O   1 
ATOM   11636 C CB  . PHE D 1 126 ? 23.187  63.803  14.786  1.00 23.46  ? 126 PHE D CB  1 
ATOM   11637 C CG  . PHE D 1 126 ? 24.014  63.950  13.520  1.00 27.05  ? 126 PHE D CG  1 
ATOM   11638 C CD1 . PHE D 1 126 ? 23.392  64.040  12.271  1.00 30.52  ? 126 PHE D CD1 1 
ATOM   11639 C CD2 . PHE D 1 126 ? 25.412  64.039  13.573  1.00 27.88  ? 126 PHE D CD2 1 
ATOM   11640 C CE1 . PHE D 1 126 ? 24.158  64.191  11.114  1.00 33.69  ? 126 PHE D CE1 1 
ATOM   11641 C CE2 . PHE D 1 126 ? 26.171  64.210  12.412  1.00 28.69  ? 126 PHE D CE2 1 
ATOM   11642 C CZ  . PHE D 1 126 ? 25.547  64.277  11.188  1.00 32.04  ? 126 PHE D CZ  1 
ATOM   11643 N N   . ASP D 1 127 ? 22.424  65.283  17.547  1.00 25.64  ? 127 ASP D N   1 
ATOM   11644 C CA  . ASP D 1 127 ? 21.720  65.190  18.813  1.00 25.12  ? 127 ASP D CA  1 
ATOM   11645 C C   . ASP D 1 127 ? 20.603  66.223  18.788  1.00 26.18  ? 127 ASP D C   1 
ATOM   11646 O O   . ASP D 1 127 ? 19.477  65.920  19.186  1.00 23.12  ? 127 ASP D O   1 
ATOM   11647 C CB  . ASP D 1 127 ? 22.629  65.348  20.010  1.00 25.78  ? 127 ASP D CB  1 
ATOM   11648 C CG  . ASP D 1 127 ? 23.661  64.243  20.203  1.00 28.10  ? 127 ASP D CG  1 
ATOM   11649 O OD1 . ASP D 1 127 ? 23.492  63.166  19.566  1.00 26.43  ? 127 ASP D OD1 1 
ATOM   11650 O OD2 . ASP D 1 127 ? 24.614  64.479  20.996  1.00 26.16  ? 127 ASP D OD2 1 
ATOM   11651 N N   . VAL D 1 128 ? 20.936  67.416  18.272  1.00 24.86  ? 128 VAL D N   1 
ATOM   11652 C CA  . VAL D 1 128 ? 20.002  68.525  18.270  1.00 25.78  ? 128 VAL D CA  1 
ATOM   11653 C C   . VAL D 1 128 ? 18.836  68.192  17.349  1.00 26.27  ? 128 VAL D C   1 
ATOM   11654 O O   . VAL D 1 128 ? 17.675  68.349  17.731  1.00 27.18  ? 128 VAL D O   1 
ATOM   11655 C CB  . VAL D 1 128 ? 20.663  69.849  17.873  1.00 27.08  ? 128 VAL D CB  1 
ATOM   11656 C CG1 . VAL D 1 128 ? 19.625  70.874  17.461  1.00 28.83  ? 128 VAL D CG1 1 
ATOM   11657 C CG2 . VAL D 1 128 ? 21.537  70.399  18.993  1.00 27.06  ? 128 VAL D CG2 1 
ATOM   11658 N N   . LEU D 1 129 ? 19.150  67.687  16.158  1.00 24.07  ? 129 LEU D N   1 
ATOM   11659 C CA  . LEU D 1 129 ? 18.113  67.406  15.186  1.00 23.96  ? 129 LEU D CA  1 
ATOM   11660 C C   . LEU D 1 129 ? 17.151  66.345  15.706  1.00 24.52  ? 129 LEU D C   1 
ATOM   11661 O O   . LEU D 1 129 ? 15.971  66.422  15.359  1.00 25.51  ? 129 LEU D O   1 
ATOM   11662 C CB  . LEU D 1 129 ? 18.742  66.963  13.874  1.00 23.07  ? 129 LEU D CB  1 
ATOM   11663 C CG  . LEU D 1 129 ? 19.424  68.069  13.082  1.00 23.20  ? 129 LEU D CG  1 
ATOM   11664 C CD1 . LEU D 1 129 ? 20.326  67.388  12.070  1.00 27.96  ? 129 LEU D CD1 1 
ATOM   11665 C CD2 . LEU D 1 129 ? 18.411  68.936  12.411  1.00 21.87  ? 129 LEU D CD2 1 
ATOM   11666 N N   . ARG D 1 130 ? 17.668  65.336  16.443  1.00 23.37  ? 130 ARG D N   1 
ATOM   11667 C CA  . ARG D 1 130 ? 16.838  64.252  16.955  1.00 25.71  ? 130 ARG D CA  1 
ATOM   11668 C C   . ARG D 1 130 ? 15.939  64.737  18.092  1.00 25.77  ? 130 ARG D C   1 
ATOM   11669 O O   . ARG D 1 130 ? 14.918  64.130  18.357  1.00 24.63  ? 130 ARG D O   1 
ATOM   11670 C CB  . ARG D 1 130 ? 17.581  63.039  17.520  1.00 27.16  ? 130 ARG D CB  1 
ATOM   11671 C CG  . ARG D 1 130 ? 18.377  62.274  16.478  1.00 29.11  ? 130 ARG D CG  1 
ATOM   11672 C CD  . ARG D 1 130 ? 18.819  60.902  16.936  1.00 28.28  ? 130 ARG D CD  1 
ATOM   11673 N NE  . ARG D 1 130 ? 17.731  59.927  17.035  1.00 30.09  ? 130 ARG D NE  1 
ATOM   11674 C CZ  . ARG D 1 130 ? 17.126  59.274  16.048  1.00 30.01  ? 130 ARG D CZ  1 
ATOM   11675 N NH1 . ARG D 1 130 ? 16.319  58.258  16.333  1.00 31.48  ? 130 ARG D NH1 1 
ATOM   11676 N NH2 . ARG D 1 130 ? 17.362  59.594  14.786  1.00 30.35  ? 130 ARG D NH2 1 
ATOM   11677 N N   . ALA D 1 131 ? 16.336  65.813  18.784  1.00 27.23  ? 131 ALA D N   1 
ATOM   11678 C CA  . ALA D 1 131 ? 15.567  66.366  19.885  1.00 25.12  ? 131 ALA D CA  1 
ATOM   11679 C C   . ALA D 1 131 ? 14.379  67.147  19.331  1.00 26.42  ? 131 ALA D C   1 
ATOM   11680 O O   . ALA D 1 131 ? 13.342  67.253  19.984  1.00 25.01  ? 131 ALA D O   1 
ATOM   11681 C CB  . ALA D 1 131 ? 16.443  67.232  20.739  1.00 25.32  ? 131 ALA D CB  1 
ATOM   11682 N N   . MET D 1 132 ? 14.518  67.668  18.103  1.00 27.15  ? 132 MET D N   1 
ATOM   11683 C CA  . MET D 1 132 ? 13.364  68.246  17.440  1.00 24.88  ? 132 MET D CA  1 
ATOM   11684 C C   . MET D 1 132 ? 12.357  67.134  17.149  1.00 24.65  ? 132 MET D C   1 
ATOM   11685 O O   . MET D 1 132 ? 12.726  66.039  16.739  1.00 26.28  ? 132 MET D O   1 
ATOM   11686 C CB  . MET D 1 132 ? 13.767  69.013  16.197  1.00 23.90  ? 132 MET D CB  1 
ATOM   11687 C CG  . MET D 1 132 ? 14.750  70.090  16.535  1.00 26.51  ? 132 MET D CG  1 
ATOM   11688 S SD  . MET D 1 132 ? 15.355  70.873  15.038  1.00 25.80  ? 132 MET D SD  1 
ATOM   11689 C CE  . MET D 1 132 ? 14.253  72.285  15.023  1.00 28.82  ? 132 MET D CE  1 
ATOM   11690 N N   . PRO D 1 133 ? 11.063  67.363  17.431  1.00 20.57  ? 133 PRO D N   1 
ATOM   11691 C CA  . PRO D 1 133 ? 10.040  66.374  17.117  1.00 22.20  ? 133 PRO D CA  1 
ATOM   11692 C C   . PRO D 1 133 ? 10.010  66.223  15.594  1.00 24.45  ? 133 PRO D C   1 
ATOM   11693 O O   . PRO D 1 133 ? 10.225  67.198  14.867  1.00 26.01  ? 133 PRO D O   1 
ATOM   11694 C CB  . PRO D 1 133 ? 8.718   66.934  17.696  1.00 20.19  ? 133 PRO D CB  1 
ATOM   11695 C CG  . PRO D 1 133 ? 9.097   68.219  18.405  1.00 19.67  ? 133 PRO D CG  1 
ATOM   11696 C CD  . PRO D 1 133 ? 10.537  68.582  18.053  1.00 19.12  ? 133 PRO D CD  1 
ATOM   11697 N N   . VAL D 1 134 ? 9.760   64.985  15.150  1.00 22.69  ? 134 VAL D N   1 
ATOM   11698 C CA  . VAL D 1 134 ? 9.935   64.598  13.769  1.00 26.04  ? 134 VAL D CA  1 
ATOM   11699 C C   . VAL D 1 134 ? 8.924   65.284  12.854  1.00 25.99  ? 134 VAL D C   1 
ATOM   11700 O O   . VAL D 1 134 ? 9.185   65.349  11.668  1.00 25.47  ? 134 VAL D O   1 
ATOM   11701 C CB  . VAL D 1 134 ? 9.863   63.063  13.627  1.00 28.65  ? 134 VAL D CB  1 
ATOM   11702 C CG1 . VAL D 1 134 ? 8.451   62.526  13.762  1.00 27.85  ? 134 VAL D CG1 1 
ATOM   11703 C CG2 . VAL D 1 134 ? 10.487  62.579  12.318  1.00 28.01  ? 134 VAL D CG2 1 
ATOM   11704 N N   . ASP D 1 135 ? 7.799   65.796  13.385  1.00 26.76  ? 135 ASP D N   1 
ATOM   11705 C CA  . ASP D 1 135 ? 6.812   66.498  12.564  1.00 26.45  ? 135 ASP D CA  1 
ATOM   11706 C C   . ASP D 1 135 ? 7.175   67.974  12.401  1.00 26.30  ? 135 ASP D C   1 
ATOM   11707 O O   . ASP D 1 135 ? 6.422   68.749  11.808  1.00 25.52  ? 135 ASP D O   1 
ATOM   11708 C CB  . ASP D 1 135 ? 5.383   66.315  13.074  1.00 26.46  ? 135 ASP D CB  1 
ATOM   11709 C CG  . ASP D 1 135 ? 5.101   66.759  14.502  1.00 28.79  ? 135 ASP D CG  1 
ATOM   11710 O OD1 . ASP D 1 135 ? 6.032   67.268  15.148  1.00 29.68  ? 135 ASP D OD1 1 
ATOM   11711 O OD2 . ASP D 1 135 ? 3.951   66.582  14.963  1.00 29.31  ? 135 ASP D OD2 1 
ATOM   11712 N N   . THR D 1 136 ? 8.338   68.375  12.922  1.00 27.03  ? 136 THR D N   1 
ATOM   11713 C CA  . THR D 1 136 ? 8.772   69.752  12.784  1.00 26.65  ? 136 THR D CA  1 
ATOM   11714 C C   . THR D 1 136 ? 8.998   70.005  11.296  1.00 26.85  ? 136 THR D C   1 
ATOM   11715 O O   . THR D 1 136 ? 9.565   69.149  10.617  1.00 26.64  ? 136 THR D O   1 
ATOM   11716 C CB  . THR D 1 136 ? 10.045  69.989  13.600  1.00 28.81  ? 136 THR D CB  1 
ATOM   11717 O OG1 . THR D 1 136 ? 9.771   69.818  14.995  1.00 24.77  ? 136 THR D OG1 1 
ATOM   11718 C CG2 . THR D 1 136 ? 10.605  71.383  13.349  1.00 29.25  ? 136 THR D CG2 1 
ATOM   11719 N N   . HIS D 1 137 ? 8.579   71.175  10.797  1.00 24.41  ? 137 HIS D N   1 
ATOM   11720 C CA  . HIS D 1 137 ? 8.851   71.545  9.414   1.00 24.39  ? 137 HIS D CA  1 
ATOM   11721 C C   . HIS D 1 137 ? 10.351  71.374  9.112   1.00 23.81  ? 137 HIS D C   1 
ATOM   11722 O O   . HIS D 1 137 ? 11.204  71.808  9.883   1.00 22.29  ? 137 HIS D O   1 
ATOM   11723 C CB  . HIS D 1 137 ? 8.360   72.968  9.125   1.00 24.39  ? 137 HIS D CB  1 
ATOM   11724 C CG  . HIS D 1 137 ? 8.364   73.277  7.674   1.00 28.78  ? 137 HIS D CG  1 
ATOM   11725 N ND1 . HIS D 1 137 ? 9.526   73.486  6.960   1.00 30.53  ? 137 HIS D ND1 1 
ATOM   11726 C CD2 . HIS D 1 137 ? 7.359   73.362  6.762   1.00 30.24  ? 137 HIS D CD2 1 
ATOM   11727 C CE1 . HIS D 1 137 ? 9.229   73.707  5.675   1.00 29.56  ? 137 HIS D CE1 1 
ATOM   11728 N NE2 . HIS D 1 137 ? 7.922   73.646  5.537   1.00 30.48  ? 137 HIS D NE2 1 
ATOM   11729 N N   . PRO D 1 138 ? 10.732  70.797  7.951   1.00 22.72  ? 138 PRO D N   1 
ATOM   11730 C CA  . PRO D 1 138 ? 12.135  70.550  7.640   1.00 23.49  ? 138 PRO D CA  1 
ATOM   11731 C C   . PRO D 1 138 ? 13.024  71.777  7.428   1.00 25.63  ? 138 PRO D C   1 
ATOM   11732 O O   . PRO D 1 138 ? 14.246  71.685  7.552   1.00 29.07  ? 138 PRO D O   1 
ATOM   11733 C CB  . PRO D 1 138 ? 12.087  69.664  6.396   1.00 23.91  ? 138 PRO D CB  1 
ATOM   11734 C CG  . PRO D 1 138 ? 10.758  69.965  5.769   1.00 24.81  ? 138 PRO D CG  1 
ATOM   11735 C CD  . PRO D 1 138 ? 9.822   70.322  6.906   1.00 23.73  ? 138 PRO D CD  1 
ATOM   11736 N N   . MET D 1 139 ? 12.442  72.928  7.119   1.00 24.07  ? 139 MET D N   1 
ATOM   11737 C CA  . MET D 1 139 ? 13.251  74.130  7.042   1.00 26.14  ? 139 MET D CA  1 
ATOM   11738 C C   . MET D 1 139 ? 13.549  74.607  8.459   1.00 27.90  ? 139 MET D C   1 
ATOM   11739 O O   . MET D 1 139 ? 14.602  75.204  8.710   1.00 30.94  ? 139 MET D O   1 
ATOM   11740 C CB  . MET D 1 139 ? 12.600  75.204  6.162   1.00 26.42  ? 139 MET D CB  1 
ATOM   11741 C CG  . MET D 1 139 ? 12.676  74.883  4.664   1.00 24.80  ? 139 MET D CG  1 
ATOM   11742 S SD  . MET D 1 139 ? 14.375  75.014  4.073   1.00 24.88  ? 139 MET D SD  1 
ATOM   11743 C CE  . MET D 1 139 ? 14.583  76.789  4.233   1.00 22.23  ? 139 MET D CE  1 
ATOM   11744 N N   . THR D 1 140 ? 12.652  74.294  9.405   1.00 29.21  ? 140 THR D N   1 
ATOM   11745 C CA  . THR D 1 140 ? 12.937  74.584  10.802  1.00 27.80  ? 140 THR D CA  1 
ATOM   11746 C C   . THR D 1 140 ? 14.100  73.701  11.250  1.00 24.01  ? 140 THR D C   1 
ATOM   11747 O O   . THR D 1 140 ? 15.046  74.170  11.846  1.00 23.26  ? 140 THR D O   1 
ATOM   11748 C CB  . THR D 1 140 ? 11.692  74.394  11.671  1.00 29.94  ? 140 THR D CB  1 
ATOM   11749 O OG1 . THR D 1 140 ? 10.708  75.239  11.062  1.00 23.61  ? 140 THR D OG1 1 
ATOM   11750 C CG2 . THR D 1 140 ? 11.985  74.709  13.140  1.00 27.42  ? 140 THR D CG2 1 
ATOM   11751 N N   . MET D 1 141 ? 14.050  72.420  10.905  1.00 23.77  ? 141 MET D N   1 
ATOM   11752 C CA  . MET D 1 141 ? 15.109  71.507  11.283  1.00 24.11  ? 141 MET D CA  1 
ATOM   11753 C C   . MET D 1 141 ? 16.433  71.948  10.681  1.00 22.86  ? 141 MET D C   1 
ATOM   11754 O O   . MET D 1 141 ? 17.435  71.973  11.372  1.00 26.96  ? 141 MET D O   1 
ATOM   11755 C CB  . MET D 1 141 ? 14.827  70.086  10.798  1.00 22.68  ? 141 MET D CB  1 
ATOM   11756 C CG  . MET D 1 141 ? 13.696  69.419  11.498  1.00 22.75  ? 141 MET D CG  1 
ATOM   11757 S SD  . MET D 1 141 ? 13.578  67.710  10.949  1.00 26.84  ? 141 MET D SD  1 
ATOM   11758 C CE  . MET D 1 141 ? 12.155  67.113  11.869  1.00 30.64  ? 141 MET D CE  1 
ATOM   11759 N N   . PHE D 1 142 ? 16.414  72.287  9.395   1.00 23.58  ? 142 PHE D N   1 
ATOM   11760 C CA  . PHE D 1 142 ? 17.611  72.664  8.659   1.00 23.52  ? 142 PHE D CA  1 
ATOM   11761 C C   . PHE D 1 142 ? 18.306  73.859  9.310   1.00 20.68  ? 142 PHE D C   1 
ATOM   11762 O O   . PHE D 1 142 ? 19.501  73.798  9.556   1.00 21.79  ? 142 PHE D O   1 
ATOM   11763 C CB  . PHE D 1 142 ? 17.258  72.967  7.189   1.00 24.91  ? 142 PHE D CB  1 
ATOM   11764 C CG  . PHE D 1 142 ? 18.401  73.092  6.182   1.00 24.73  ? 142 PHE D CG  1 
ATOM   11765 C CD1 . PHE D 1 142 ? 19.345  72.077  6.033   1.00 26.49  ? 142 PHE D CD1 1 
ATOM   11766 C CD2 . PHE D 1 142 ? 18.516  74.219  5.375   1.00 26.28  ? 142 PHE D CD2 1 
ATOM   11767 C CE1 . PHE D 1 142 ? 20.367  72.181  5.099   1.00 29.61  ? 142 PHE D CE1 1 
ATOM   11768 C CE2 . PHE D 1 142 ? 19.548  74.332  4.448   1.00 26.70  ? 142 PHE D CE2 1 
ATOM   11769 C CZ  . PHE D 1 142 ? 20.471  73.314  4.308   1.00 28.70  ? 142 PHE D CZ  1 
ATOM   11770 N N   . ALA D 1 143 ? 17.589  74.974  9.484   1.00 20.15  ? 143 ALA D N   1 
ATOM   11771 C CA  . ALA D 1 143 ? 18.195  76.168  10.046  1.00 21.98  ? 143 ALA D CA  1 
ATOM   11772 C C   . ALA D 1 143 ? 18.739  75.883  11.453  1.00 24.28  ? 143 ALA D C   1 
ATOM   11773 O O   . ALA D 1 143 ? 19.830  76.336  11.786  1.00 26.49  ? 143 ALA D O   1 
ATOM   11774 C CB  . ALA D 1 143 ? 17.218  77.336  10.003  1.00 21.21  ? 143 ALA D CB  1 
ATOM   11775 N N   . ALA D 1 144 ? 18.015  75.111  12.275  1.00 26.56  ? 144 ALA D N   1 
ATOM   11776 C CA  . ALA D 1 144 ? 18.469  74.784  13.628  1.00 26.84  ? 144 ALA D CA  1 
ATOM   11777 C C   . ALA D 1 144 ? 19.771  73.995  13.586  1.00 25.89  ? 144 ALA D C   1 
ATOM   11778 O O   . ALA D 1 144 ? 20.658  74.245  14.386  1.00 25.16  ? 144 ALA D O   1 
ATOM   11779 C CB  . ALA D 1 144 ? 17.435  73.978  14.365  1.00 26.03  ? 144 ALA D CB  1 
ATOM   11780 N N   . GLY D 1 145 ? 19.857  73.008  12.686  1.00 25.71  ? 145 GLY D N   1 
ATOM   11781 C CA  . GLY D 1 145 ? 21.056  72.185  12.582  1.00 26.74  ? 145 GLY D CA  1 
ATOM   11782 C C   . GLY D 1 145 ? 22.286  73.027  12.243  1.00 25.57  ? 145 GLY D C   1 
ATOM   11783 O O   . GLY D 1 145 ? 23.337  72.880  12.842  1.00 27.09  ? 145 GLY D O   1 
ATOM   11784 N N   . ILE D 1 146 ? 22.116  73.938  11.288  1.00 24.07  ? 146 ILE D N   1 
ATOM   11785 C CA  . ILE D 1 146 ? 23.166  74.836  10.872  1.00 24.73  ? 146 ILE D CA  1 
ATOM   11786 C C   . ILE D 1 146 ? 23.593  75.731  12.035  1.00 24.37  ? 146 ILE D C   1 
ATOM   11787 O O   . ILE D 1 146 ? 24.781  75.900  12.295  1.00 23.20  ? 146 ILE D O   1 
ATOM   11788 C CB  . ILE D 1 146 ? 22.656  75.615  9.656   1.00 25.69  ? 146 ILE D CB  1 
ATOM   11789 C CG1 . ILE D 1 146 ? 22.464  74.671  8.473   1.00 25.39  ? 146 ILE D CG1 1 
ATOM   11790 C CG2 . ILE D 1 146 ? 23.582  76.773  9.297   1.00 27.70  ? 146 ILE D CG2 1 
ATOM   11791 C CD1 . ILE D 1 146 ? 21.503  75.183  7.417   1.00 25.11  ? 146 ILE D CD1 1 
ATOM   11792 N N   . LEU D 1 147 ? 22.614  76.286  12.744  1.00 24.58  ? 147 LEU D N   1 
ATOM   11793 C CA  . LEU D 1 147 ? 22.879  77.238  13.810  1.00 25.10  ? 147 LEU D CA  1 
ATOM   11794 C C   . LEU D 1 147 ? 23.649  76.581  14.957  1.00 24.07  ? 147 LEU D C   1 
ATOM   11795 O O   . LEU D 1 147 ? 24.529  77.193  15.542  1.00 23.98  ? 147 LEU D O   1 
ATOM   11796 C CB  . LEU D 1 147 ? 21.549  77.785  14.299  1.00 24.37  ? 147 LEU D CB  1 
ATOM   11797 C CG  . LEU D 1 147 ? 21.637  78.807  15.432  1.00 27.54  ? 147 LEU D CG  1 
ATOM   11798 C CD1 . LEU D 1 147 ? 22.642  79.921  15.172  1.00 28.36  ? 147 LEU D CD1 1 
ATOM   11799 C CD2 . LEU D 1 147 ? 20.255  79.383  15.658  1.00 27.49  ? 147 LEU D CD2 1 
ATOM   11800 N N   . ALA D 1 148 ? 23.281  75.352  15.299  1.00 20.86  ? 148 ALA D N   1 
ATOM   11801 C CA  . ALA D 1 148 ? 23.961  74.619  16.339  1.00 21.75  ? 148 ALA D CA  1 
ATOM   11802 C C   . ALA D 1 148 ? 25.435  74.457  16.005  1.00 23.31  ? 148 ALA D C   1 
ATOM   11803 O O   . ALA D 1 148 ? 26.245  74.260  16.905  1.00 26.56  ? 148 ALA D O   1 
ATOM   11804 C CB  . ALA D 1 148 ? 23.333  73.261  16.528  1.00 22.12  ? 148 ALA D CB  1 
ATOM   11805 N N   . MET D 1 149 ? 25.773  74.471  14.711  1.00 24.06  ? 149 MET D N   1 
ATOM   11806 C CA  . MET D 1 149 ? 27.142  74.223  14.305  1.00 21.56  ? 149 MET D CA  1 
ATOM   11807 C C   . MET D 1 149 ? 27.962  75.502  14.461  1.00 21.62  ? 149 MET D C   1 
ATOM   11808 O O   . MET D 1 149 ? 29.175  75.502  14.313  1.00 23.38  ? 149 MET D O   1 
ATOM   11809 C CB  . MET D 1 149 ? 27.175  73.688  12.879  1.00 22.57  ? 149 MET D CB  1 
ATOM   11810 C CG  . MET D 1 149 ? 28.509  73.168  12.464  1.00 23.63  ? 149 MET D CG  1 
ATOM   11811 S SD  . MET D 1 149 ? 28.376  72.094  11.025  1.00 27.22  ? 149 MET D SD  1 
ATOM   11812 C CE  . MET D 1 149 ? 30.107  72.056  10.553  1.00 26.83  ? 149 MET D CE  1 
ATOM   11813 N N   . GLN D 1 150 ? 27.309  76.594  14.842  1.00 22.53  ? 150 GLN D N   1 
ATOM   11814 C CA  . GLN D 1 150 ? 27.983  77.854  15.089  1.00 21.80  ? 150 GLN D CA  1 
ATOM   11815 C C   . GLN D 1 150 ? 29.078  77.723  16.139  1.00 22.16  ? 150 GLN D C   1 
ATOM   11816 O O   . GLN D 1 150 ? 29.979  78.550  16.140  1.00 20.00  ? 150 GLN D O   1 
ATOM   11817 C CB  . GLN D 1 150 ? 26.971  78.903  15.534  1.00 20.81  ? 150 GLN D CB  1 
ATOM   11818 C CG  . GLN D 1 150 ? 27.527  80.321  15.630  1.00 22.52  ? 150 GLN D CG  1 
ATOM   11819 C CD  . GLN D 1 150 ? 28.355  80.618  16.867  1.00 22.62  ? 150 GLN D CD  1 
ATOM   11820 O OE1 . GLN D 1 150 ? 29.317  81.398  16.850  1.00 21.09  ? 150 GLN D OE1 1 
ATOM   11821 N NE2 . GLN D 1 150 ? 27.924  80.058  17.982  1.00 24.35  ? 150 GLN D NE2 1 
ATOM   11822 N N   . ARG D 1 151 ? 29.002  76.714  17.024  1.00 23.41  ? 151 ARG D N   1 
ATOM   11823 C CA  . ARG D 1 151 ? 30.046  76.483  18.017  1.00 23.10  ? 151 ARG D CA  1 
ATOM   11824 C C   . ARG D 1 151 ? 31.416  76.213  17.371  1.00 24.30  ? 151 ARG D C   1 
ATOM   11825 O O   . ARG D 1 151 ? 32.444  76.543  17.957  1.00 22.24  ? 151 ARG D O   1 
ATOM   11826 C CB  . ARG D 1 151 ? 29.644  75.317  18.909  1.00 24.53  ? 151 ARG D CB  1 
ATOM   11827 C CG  . ARG D 1 151 ? 30.703  74.876  19.912  1.00 26.66  ? 151 ARG D CG  1 
ATOM   11828 C CD  . ARG D 1 151 ? 30.263  73.582  20.599  1.00 28.89  ? 151 ARG D CD  1 
ATOM   11829 N NE  . ARG D 1 151 ? 31.210  73.157  21.636  1.00 32.40  ? 151 ARG D NE  1 
ATOM   11830 C CZ  . ARG D 1 151 ? 32.192  72.260  21.474  1.00 35.70  ? 151 ARG D CZ  1 
ATOM   11831 N NH1 . ARG D 1 151 ? 32.495  71.766  20.277  1.00 40.83  ? 151 ARG D NH1 1 
ATOM   11832 N NH2 . ARG D 1 151 ? 32.891  71.864  22.515  1.00 31.69  ? 151 ARG D NH2 1 
ATOM   11833 N N   . GLU D 1 152 ? 31.452  75.628  16.162  1.00 25.50  ? 152 GLU D N   1 
ATOM   11834 C CA  . GLU D 1 152 ? 32.707  75.400  15.458  1.00 24.05  ? 152 GLU D CA  1 
ATOM   11835 C C   . GLU D 1 152 ? 33.101  76.569  14.555  1.00 22.90  ? 152 GLU D C   1 
ATOM   11836 O O   . GLU D 1 152 ? 33.975  76.400  13.715  1.00 22.62  ? 152 GLU D O   1 
ATOM   11837 C CB  . GLU D 1 152 ? 32.641  74.161  14.576  1.00 24.97  ? 152 GLU D CB  1 
ATOM   11838 C CG  . GLU D 1 152 ? 32.000  72.983  15.293  1.00 27.73  ? 152 GLU D CG  1 
ATOM   11839 C CD  . GLU D 1 152 ? 32.563  72.673  16.661  1.00 30.05  ? 152 GLU D CD  1 
ATOM   11840 O OE1 . GLU D 1 152 ? 31.762  72.491  17.610  1.00 31.95  ? 152 GLU D OE1 1 
ATOM   11841 O OE2 . GLU D 1 152 ? 33.804  72.597  16.755  1.00 31.22  ? 152 GLU D OE2 1 
ATOM   11842 N N   . SER D 1 153 ? 32.492  77.749  14.727  1.00 23.49  ? 153 SER D N   1 
ATOM   11843 C CA  . SER D 1 153 ? 32.791  78.878  13.858  1.00 25.27  ? 153 SER D CA  1 
ATOM   11844 C C   . SER D 1 153 ? 34.217  79.370  14.093  1.00 28.69  ? 153 SER D C   1 
ATOM   11845 O O   . SER D 1 153 ? 34.580  79.693  15.217  1.00 31.85  ? 153 SER D O   1 
ATOM   11846 C CB  . SER D 1 153 ? 31.857  80.028  14.059  1.00 24.95  ? 153 SER D CB  1 
ATOM   11847 O OG  . SER D 1 153 ? 32.390  81.165  13.398  1.00 26.67  ? 153 SER D OG  1 
ATOM   11848 N N   . VAL D 1 154 ? 34.980  79.513  13.008  1.00 29.37  ? 154 VAL D N   1 
ATOM   11849 C CA  . VAL D 1 154 ? 36.353  79.981  13.066  1.00 29.86  ? 154 VAL D CA  1 
ATOM   11850 C C   . VAL D 1 154 ? 36.335  81.502  13.096  1.00 30.19  ? 154 VAL D C   1 
ATOM   11851 O O   . VAL D 1 154 ? 37.034  82.128  13.878  1.00 31.72  ? 154 VAL D O   1 
ATOM   11852 C CB  . VAL D 1 154 ? 37.154  79.401  11.887  1.00 30.44  ? 154 VAL D CB  1 
ATOM   11853 C CG1 . VAL D 1 154 ? 38.459  80.129  11.663  1.00 32.36  ? 154 VAL D CG1 1 
ATOM   11854 C CG2 . VAL D 1 154 ? 37.405  77.910  12.089  1.00 29.60  ? 154 VAL D CG2 1 
ATOM   11855 N N   . PHE D 1 155 ? 35.456  82.104  12.313  1.00 29.91  ? 155 PHE D N   1 
ATOM   11856 C CA  . PHE D 1 155 ? 35.307  83.546  12.366  1.00 29.45  ? 155 PHE D CA  1 
ATOM   11857 C C   . PHE D 1 155 ? 35.008  84.002  13.804  1.00 31.77  ? 155 PHE D C   1 
ATOM   11858 O O   . PHE D 1 155 ? 35.547  85.001  14.283  1.00 29.61  ? 155 PHE D O   1 
ATOM   11859 C CB  . PHE D 1 155 ? 34.210  83.899  11.357  1.00 27.80  ? 155 PHE D CB  1 
ATOM   11860 C CG  . PHE D 1 155 ? 34.082  85.396  11.215  1.00 25.27  ? 155 PHE D CG  1 
ATOM   11861 C CD1 . PHE D 1 155 ? 33.370  86.132  12.139  1.00 25.94  ? 155 PHE D CD1 1 
ATOM   11862 C CD2 . PHE D 1 155 ? 34.755  86.063  10.213  1.00 25.86  ? 155 PHE D CD2 1 
ATOM   11863 C CE1 . PHE D 1 155 ? 33.287  87.508  12.038  1.00 27.21  ? 155 PHE D CE1 1 
ATOM   11864 C CE2 . PHE D 1 155 ? 34.665  87.438  10.101  1.00 26.11  ? 155 PHE D CE2 1 
ATOM   11865 C CZ  . PHE D 1 155 ? 33.940  88.158  11.019  1.00 28.18  ? 155 PHE D CZ  1 
ATOM   11866 N N   . ALA D 1 156 ? 34.123  83.283  14.503  1.00 31.12  ? 156 ALA D N   1 
ATOM   11867 C CA  . ALA D 1 156 ? 33.685  83.733  15.817  1.00 31.21  ? 156 ALA D CA  1 
ATOM   11868 C C   . ALA D 1 156 ? 34.855  83.670  16.784  1.00 27.45  ? 156 ALA D C   1 
ATOM   11869 O O   . ALA D 1 156 ? 35.093  84.626  17.496  1.00 23.96  ? 156 ALA D O   1 
ATOM   11870 C CB  . ALA D 1 156 ? 32.496  82.938  16.339  1.00 31.06  ? 156 ALA D CB  1 
ATOM   11871 N N   . LYS D 1 157 ? 35.578  82.548  16.774  1.00 30.46  ? 157 LYS D N   1 
ATOM   11872 C CA  . LYS D 1 157 ? 36.721  82.337  17.655  1.00 32.55  ? 157 LYS D CA  1 
ATOM   11873 C C   . LYS D 1 157 ? 37.817  83.367  17.372  1.00 30.93  ? 157 LYS D C   1 
ATOM   11874 O O   . LYS D 1 157 ? 38.273  84.040  18.280  1.00 29.13  ? 157 LYS D O   1 
ATOM   11875 C CB  . LYS D 1 157 ? 37.181  80.893  17.469  1.00 33.96  ? 157 LYS D CB  1 
ATOM   11876 C CG  . LYS D 1 157 ? 38.424  80.473  18.207  1.00 40.53  ? 157 LYS D CG  1 
ATOM   11877 C CD  . LYS D 1 157 ? 38.886  79.134  17.638  1.00 52.47  ? 157 LYS D CD  1 
ATOM   11878 C CE  . LYS D 1 157 ? 40.365  78.894  17.679  1.00 57.88  ? 157 LYS D CE  1 
ATOM   11879 N NZ  . LYS D 1 157 ? 40.661  78.262  18.961  1.00 63.26  ? 157 LYS D NZ  1 
ATOM   11880 N N   . ARG D 1 158 ? 38.205  83.505  16.101  1.00 32.69  ? 158 ARG D N   1 
ATOM   11881 C CA  . ARG D 1 158 ? 39.246  84.436  15.682  1.00 31.14  ? 158 ARG D CA  1 
ATOM   11882 C C   . ARG D 1 158 ? 38.844  85.875  15.978  1.00 27.98  ? 158 ARG D C   1 
ATOM   11883 O O   . ARG D 1 158 ? 39.715  86.681  16.333  1.00 25.91  ? 158 ARG D O   1 
ATOM   11884 C CB  . ARG D 1 158 ? 39.672  84.244  14.215  1.00 35.64  ? 158 ARG D CB  1 
ATOM   11885 C CG  . ARG D 1 158 ? 40.972  83.458  14.087  1.00 44.42  ? 158 ARG D CG  1 
ATOM   11886 C CD  . ARG D 1 158 ? 40.967  82.322  13.074  1.00 50.34  ? 158 ARG D CD  1 
ATOM   11887 N NE  . ARG D 1 158 ? 41.234  82.755  11.697  1.00 58.34  ? 158 ARG D NE  1 
ATOM   11888 C CZ  . ARG D 1 158 ? 41.513  81.945  10.666  1.00 58.24  ? 158 ARG D CZ  1 
ATOM   11889 N NH1 . ARG D 1 158 ? 41.538  82.462  9.445   1.00 52.89  ? 158 ARG D NH1 1 
ATOM   11890 N NH2 . ARG D 1 158 ? 41.723  80.639  10.852  1.00 51.43  ? 158 ARG D NH2 1 
ATOM   11891 N N   . TYR D 1 159 ? 37.547  86.190  15.863  1.00 24.20  ? 159 TYR D N   1 
ATOM   11892 C CA  . TYR D 1 159 ? 37.129  87.554  16.115  1.00 26.74  ? 159 TYR D CA  1 
ATOM   11893 C C   . TYR D 1 159 ? 37.484  87.913  17.555  1.00 29.34  ? 159 TYR D C   1 
ATOM   11894 O O   . TYR D 1 159 ? 38.010  88.993  17.805  1.00 28.33  ? 159 TYR D O   1 
ATOM   11895 C CB  . TYR D 1 159 ? 35.645  87.857  15.899  1.00 27.31  ? 159 TYR D CB  1 
ATOM   11896 C CG  . TYR D 1 159 ? 35.308  89.295  16.266  1.00 26.71  ? 159 TYR D CG  1 
ATOM   11897 C CD1 . TYR D 1 159 ? 35.410  90.314  15.341  1.00 25.93  ? 159 TYR D CD1 1 
ATOM   11898 C CD2 . TYR D 1 159 ? 34.953  89.644  17.560  1.00 25.17  ? 159 TYR D CD2 1 
ATOM   11899 C CE1 . TYR D 1 159 ? 35.154  91.629  15.690  1.00 26.23  ? 159 TYR D CE1 1 
ATOM   11900 C CE2 . TYR D 1 159 ? 34.680  90.950  17.917  1.00 23.55  ? 159 TYR D CE2 1 
ATOM   11901 C CZ  . TYR D 1 159 ? 34.783  91.952  16.982  1.00 25.09  ? 159 TYR D CZ  1 
ATOM   11902 O OH  . TYR D 1 159 ? 34.505  93.252  17.332  1.00 25.29  ? 159 TYR D OH  1 
ATOM   11903 N N   . GLU D 1 160 ? 37.184  86.994  18.483  1.00 33.23  ? 160 GLU D N   1 
ATOM   11904 C CA  . GLU D 1 160 ? 37.381  87.194  19.918  1.00 37.01  ? 160 GLU D CA  1 
ATOM   11905 C C   . GLU D 1 160 ? 38.872  87.239  20.278  1.00 33.17  ? 160 GLU D C   1 
ATOM   11906 O O   . GLU D 1 160 ? 39.249  88.034  21.131  1.00 29.61  ? 160 GLU D O   1 
ATOM   11907 C CB  . GLU D 1 160 ? 36.675  86.134  20.779  1.00 41.80  ? 160 GLU D CB  1 
ATOM   11908 C CG  . GLU D 1 160 ? 35.144  86.216  20.739  1.00 53.20  ? 160 GLU D CG  1 
ATOM   11909 C CD  . GLU D 1 160 ? 34.433  87.389  21.434  1.00 54.64  ? 160 GLU D CD  1 
ATOM   11910 O OE1 . GLU D 1 160 ? 33.815  88.268  20.776  1.00 49.24  ? 160 GLU D OE1 1 
ATOM   11911 O OE2 . GLU D 1 160 ? 34.443  87.379  22.684  1.00 58.96  ? 160 GLU D OE2 1 
ATOM   11912 N N   . GLU D 1 161 ? 39.692  86.367  19.667  1.00 31.57  ? 161 GLU D N   1 
ATOM   11913 C CA  . GLU D 1 161 ? 41.136  86.356  19.868  1.00 32.65  ? 161 GLU D CA  1 
ATOM   11914 C C   . GLU D 1 161 ? 41.736  87.679  19.403  1.00 31.34  ? 161 GLU D C   1 
ATOM   11915 O O   . GLU D 1 161 ? 42.646  88.190  20.016  1.00 37.47  ? 161 GLU D O   1 
ATOM   11916 C CB  . GLU D 1 161 ? 41.838  85.205  19.151  1.00 33.72  ? 161 GLU D CB  1 
ATOM   11917 C CG  . GLU D 1 161 ? 41.386  83.824  19.625  1.00 35.82  ? 161 GLU D CG  1 
ATOM   11918 C CD  . GLU D 1 161 ? 41.904  82.650  18.801  1.00 41.49  ? 161 GLU D CD  1 
ATOM   11919 O OE1 . GLU D 1 161 ? 41.909  81.520  19.344  1.00 42.19  ? 161 GLU D OE1 1 
ATOM   11920 O OE2 . GLU D 1 161 ? 42.301  82.842  17.623  1.00 43.36  ? 161 GLU D OE2 1 
ATOM   11921 N N   . GLY D 1 162 ? 41.191  88.260  18.348  1.00 35.42  ? 162 GLY D N   1 
ATOM   11922 C CA  . GLY D 1 162 ? 41.668  89.530  17.823  1.00 35.93  ? 162 GLY D CA  1 
ATOM   11923 C C   . GLY D 1 162 ? 42.178  89.326  16.405  1.00 34.90  ? 162 GLY D C   1 
ATOM   11924 O O   . GLY D 1 162 ? 43.081  88.523  16.205  1.00 42.37  ? 162 GLY D O   1 
ATOM   11925 N N   . MET D 1 163 ? 41.523  89.947  15.424  1.00 34.43  ? 163 MET D N   1 
ATOM   11926 C CA  . MET D 1 163 ? 41.972  89.860  14.040  1.00 31.63  ? 163 MET D CA  1 
ATOM   11927 C C   . MET D 1 163 ? 41.583  91.153  13.357  1.00 29.11  ? 163 MET D C   1 
ATOM   11928 O O   . MET D 1 163 ? 40.620  91.778  13.748  1.00 30.98  ? 163 MET D O   1 
ATOM   11929 C CB  . MET D 1 163 ? 41.431  88.638  13.279  1.00 32.46  ? 163 MET D CB  1 
ATOM   11930 C CG  . MET D 1 163 ? 39.960  88.659  12.868  1.00 35.19  ? 163 MET D CG  1 
ATOM   11931 S SD  . MET D 1 163 ? 39.458  87.281  11.795  1.00 31.91  ? 163 MET D SD  1 
ATOM   11932 C CE  . MET D 1 163 ? 37.693  87.236  12.132  1.00 28.93  ? 163 MET D CE  1 
ATOM   11933 N N   . ARG D 1 164 ? 42.363  91.565  12.365  1.00 33.21  ? 164 ARG D N   1 
ATOM   11934 C CA  . ARG D 1 164 ? 42.076  92.801  11.654  1.00 33.76  ? 164 ARG D CA  1 
ATOM   11935 C C   . ARG D 1 164 ? 41.080  92.460  10.545  1.00 31.70  ? 164 ARG D C   1 
ATOM   11936 O O   . ARG D 1 164 ? 40.874  91.288  10.198  1.00 25.38  ? 164 ARG D O   1 
ATOM   11937 C CB  . ARG D 1 164 ? 43.399  93.432  11.191  1.00 37.04  ? 164 ARG D CB  1 
ATOM   11938 C CG  . ARG D 1 164 ? 44.542  93.296  12.194  1.00 37.90  ? 164 ARG D CG  1 
ATOM   11939 C CD  . ARG D 1 164 ? 45.867  93.929  11.773  1.00 40.98  ? 164 ARG D CD  1 
ATOM   11940 N NE  . ARG D 1 164 ? 45.770  95.390  11.724  1.00 41.58  ? 164 ARG D NE  1 
ATOM   11941 C CZ  . ARG D 1 164 ? 46.271  96.258  12.598  1.00 43.06  ? 164 ARG D CZ  1 
ATOM   11942 N NH1 . ARG D 1 164 ? 45.877  97.514  12.536  1.00 47.08  ? 164 ARG D NH1 1 
ATOM   11943 N NH2 . ARG D 1 164 ? 47.079  95.892  13.575  1.00 42.62  ? 164 ARG D NH2 1 
ATOM   11944 N N   . ARG D 1 165 ? 40.450  93.498  9.998   1.00 31.67  ? 165 ARG D N   1 
ATOM   11945 C CA  . ARG D 1 165 ? 39.426  93.309  8.977   1.00 34.43  ? 165 ARG D CA  1 
ATOM   11946 C C   . ARG D 1 165 ? 39.955  92.534  7.760   1.00 31.66  ? 165 ARG D C   1 
ATOM   11947 O O   . ARG D 1 165 ? 39.220  91.735  7.190   1.00 32.00  ? 165 ARG D O   1 
ATOM   11948 C CB  . ARG D 1 165 ? 38.791  94.657  8.610   1.00 36.36  ? 165 ARG D CB  1 
ATOM   11949 C CG  . ARG D 1 165 ? 37.847  95.169  9.689   1.00 40.29  ? 165 ARG D CG  1 
ATOM   11950 C CD  . ARG D 1 165 ? 37.082  96.434  9.333   1.00 39.74  ? 165 ARG D CD  1 
ATOM   11951 N NE  . ARG D 1 165 ? 38.075  97.493  9.196   1.00 41.22  ? 165 ARG D NE  1 
ATOM   11952 C CZ  . ARG D 1 165 ? 37.816  98.757  8.936   1.00 44.32  ? 165 ARG D CZ  1 
ATOM   11953 N NH1 . ARG D 1 165 ? 38.819  99.621  8.857   1.00 48.35  ? 165 ARG D NH1 1 
ATOM   11954 N NH2 . ARG D 1 165 ? 36.575  99.163  8.759   1.00 39.38  ? 165 ARG D NH2 1 
ATOM   11955 N N   . GLU D 1 166 ? 41.232  92.729  7.399   1.00 33.82  ? 166 GLU D N   1 
ATOM   11956 C CA  . GLU D 1 166 ? 41.857  92.120  6.230   1.00 36.91  ? 166 GLU D CA  1 
ATOM   11957 C C   . GLU D 1 166 ? 41.791  90.595  6.312   1.00 38.08  ? 166 GLU D C   1 
ATOM   11958 O O   . GLU D 1 166 ? 41.755  89.934  5.270   1.00 35.89  ? 166 GLU D O   1 
ATOM   11959 C CB  . GLU D 1 166 ? 43.325  92.545  6.091   1.00 44.84  ? 166 GLU D CB  1 
ATOM   11960 C CG  . GLU D 1 166 ? 43.549  94.001  5.661   1.00 49.75  ? 166 GLU D CG  1 
ATOM   11961 C CD  . GLU D 1 166 ? 43.189  95.115  6.662   1.00 53.19  ? 166 GLU D CD  1 
ATOM   11962 O OE1 . GLU D 1 166 ? 43.349  96.305  6.317   1.00 52.29  ? 166 GLU D OE1 1 
ATOM   11963 O OE2 . GLU D 1 166 ? 42.737  94.826  7.794   1.00 48.08  ? 166 GLU D OE2 1 
ATOM   11964 N N   . GLU D 1 167 ? 41.750  90.051  7.546   1.00 35.53  ? 167 GLU D N   1 
ATOM   11965 C CA  . GLU D 1 167 ? 41.798  88.613  7.723   1.00 35.40  ? 167 GLU D CA  1 
ATOM   11966 C C   . GLU D 1 167 ? 40.398  88.019  7.680   1.00 29.73  ? 167 GLU D C   1 
ATOM   11967 O O   . GLU D 1 167 ? 40.291  86.799  7.731   1.00 30.06  ? 167 GLU D O   1 
ATOM   11968 C CB  . GLU D 1 167 ? 42.407  88.147  9.039   1.00 43.72  ? 167 GLU D CB  1 
ATOM   11969 C CG  . GLU D 1 167 ? 43.856  88.573  9.258   1.00 55.23  ? 167 GLU D CG  1 
ATOM   11970 C CD  . GLU D 1 167 ? 44.262  88.598  10.735  1.00 69.04  ? 167 GLU D CD  1 
ATOM   11971 O OE1 . GLU D 1 167 ? 44.147  87.510  11.389  1.00 68.36  ? 167 GLU D OE1 1 
ATOM   11972 O OE2 . GLU D 1 167 ? 44.664  89.701  11.235  1.00 57.83  ? 167 GLU D OE2 1 
ATOM   11973 N N   . HIS D 1 168 ? 39.342  88.841  7.607   1.00 24.01  ? 168 HIS D N   1 
ATOM   11974 C CA  . HIS D 1 168 ? 37.990  88.306  7.736   1.00 26.08  ? 168 HIS D CA  1 
ATOM   11975 C C   . HIS D 1 168 ? 37.673  87.262  6.652   1.00 26.42  ? 168 HIS D C   1 
ATOM   11976 O O   . HIS D 1 168 ? 37.078  86.213  6.911   1.00 22.74  ? 168 HIS D O   1 
ATOM   11977 C CB  . HIS D 1 168 ? 36.951  89.420  7.665   1.00 25.95  ? 168 HIS D CB  1 
ATOM   11978 C CG  . HIS D 1 168 ? 36.831  90.229  8.900   1.00 26.79  ? 168 HIS D CG  1 
ATOM   11979 N ND1 . HIS D 1 168 ? 35.869  91.205  9.033   1.00 25.78  ? 168 HIS D ND1 1 
ATOM   11980 C CD2 . HIS D 1 168 ? 37.541  90.227  10.041  1.00 27.47  ? 168 HIS D CD2 1 
ATOM   11981 C CE1 . HIS D 1 168 ? 35.980  91.745  10.230  1.00 27.23  ? 168 HIS D CE1 1 
ATOM   11982 N NE2 . HIS D 1 168 ? 37.001  91.178  10.854  1.00 27.85  ? 168 HIS D NE2 1 
ATOM   11983 N N   . TRP D 1 169 ? 38.081  87.546  5.412   1.00 26.26  ? 169 TRP D N   1 
ATOM   11984 C CA  . TRP D 1 169 ? 37.675  86.704  4.310   1.00 24.26  ? 169 TRP D CA  1 
ATOM   11985 C C   . TRP D 1 169 ? 38.198  85.287  4.512   1.00 25.70  ? 169 TRP D C   1 
ATOM   11986 O O   . TRP D 1 169 ? 37.515  84.329  4.147   1.00 26.29  ? 169 TRP D O   1 
ATOM   11987 C CB  . TRP D 1 169 ? 38.080  87.319  2.960   1.00 25.30  ? 169 TRP D CB  1 
ATOM   11988 C CG  . TRP D 1 169 ? 39.536  87.330  2.613   1.00 24.56  ? 169 TRP D CG  1 
ATOM   11989 C CD1 . TRP D 1 169 ? 40.428  88.347  2.817   1.00 24.32  ? 169 TRP D CD1 1 
ATOM   11990 C CD2 . TRP D 1 169 ? 40.268  86.255  1.988   1.00 24.88  ? 169 TRP D CD2 1 
ATOM   11991 N NE1 . TRP D 1 169 ? 41.664  87.966  2.373   1.00 22.37  ? 169 TRP D NE1 1 
ATOM   11992 C CE2 . TRP D 1 169 ? 41.597  86.697  1.857   1.00 22.89  ? 169 TRP D CE2 1 
ATOM   11993 C CE3 . TRP D 1 169 ? 39.938  84.973  1.536   1.00 24.93  ? 169 TRP D CE3 1 
ATOM   11994 C CZ2 . TRP D 1 169 ? 42.581  85.894  1.293   1.00 23.20  ? 169 TRP D CZ2 1 
ATOM   11995 C CZ3 . TRP D 1 169 ? 40.921  84.184  0.982   1.00 22.28  ? 169 TRP D CZ3 1 
ATOM   11996 C CH2 . TRP D 1 169 ? 42.223  84.634  0.878   1.00 22.50  ? 169 TRP D CH2 1 
ATOM   11997 N N   . GLU D 1 170 ? 39.380  85.156  5.123   1.00 24.79  ? 170 GLU D N   1 
ATOM   11998 C CA  . GLU D 1 170 ? 40.000  83.847  5.267   1.00 28.20  ? 170 GLU D CA  1 
ATOM   11999 C C   . GLU D 1 170 ? 39.219  82.993  6.271   1.00 26.46  ? 170 GLU D C   1 
ATOM   12000 O O   . GLU D 1 170 ? 39.022  81.789  6.082   1.00 28.34  ? 170 GLU D O   1 
ATOM   12001 C CB  . GLU D 1 170 ? 41.467  83.966  5.697   1.00 31.41  ? 170 GLU D CB  1 
ATOM   12002 C CG  . GLU D 1 170 ? 42.301  84.896  4.826   1.00 33.55  ? 170 GLU D CG  1 
ATOM   12003 C CD  . GLU D 1 170 ? 43.788  84.836  5.106   1.00 36.49  ? 170 GLU D CD  1 
ATOM   12004 O OE1 . GLU D 1 170 ? 44.364  85.935  5.220   1.00 36.50  ? 170 GLU D OE1 1 
ATOM   12005 O OE2 . GLU D 1 170 ? 44.355  83.722  5.185   1.00 36.62  ? 170 GLU D OE2 1 
ATOM   12006 N N   . ALA D 1 171 ? 38.796  83.626  7.359   1.00 24.85  ? 171 ALA D N   1 
ATOM   12007 C CA  . ALA D 1 171 ? 37.945  82.966  8.325   1.00 24.92  ? 171 ALA D CA  1 
ATOM   12008 C C   . ALA D 1 171 ? 36.591  82.633  7.703   1.00 25.16  ? 171 ALA D C   1 
ATOM   12009 O O   . ALA D 1 171 ? 36.080  81.538  7.923   1.00 26.39  ? 171 ALA D O   1 
ATOM   12010 C CB  . ALA D 1 171 ? 37.813  83.824  9.555   1.00 23.95  ? 171 ALA D CB  1 
ATOM   12011 N N   . MET D 1 172 ? 36.020  83.557  6.928   1.00 24.73  ? 172 MET D N   1 
ATOM   12012 C CA  . MET D 1 172 ? 34.749  83.299  6.267   1.00 26.39  ? 172 MET D CA  1 
ATOM   12013 C C   . MET D 1 172 ? 34.874  82.146  5.269   1.00 26.08  ? 172 MET D C   1 
ATOM   12014 O O   . MET D 1 172 ? 33.953  81.354  5.100   1.00 26.00  ? 172 MET D O   1 
ATOM   12015 C CB  . MET D 1 172 ? 34.252  84.544  5.530   1.00 26.69  ? 172 MET D CB  1 
ATOM   12016 C CG  . MET D 1 172 ? 33.843  85.672  6.453   1.00 27.31  ? 172 MET D CG  1 
ATOM   12017 S SD  . MET D 1 172 ? 32.359  85.379  7.444   1.00 30.14  ? 172 MET D SD  1 
ATOM   12018 C CE  . MET D 1 172 ? 31.326  84.518  6.256   1.00 29.55  ? 172 MET D CE  1 
ATOM   12019 N N   . LEU D 1 173 ? 36.014  82.025  4.606   1.00 27.06  ? 173 LEU D N   1 
ATOM   12020 C CA  . LEU D 1 173 ? 36.187  80.938  3.654   1.00 30.81  ? 173 LEU D CA  1 
ATOM   12021 C C   . LEU D 1 173 ? 36.224  79.593  4.391   1.00 31.55  ? 173 LEU D C   1 
ATOM   12022 O O   . LEU D 1 173 ? 35.564  78.627  3.990   1.00 31.63  ? 173 LEU D O   1 
ATOM   12023 C CB  . LEU D 1 173 ? 37.437  81.178  2.808   1.00 30.95  ? 173 LEU D CB  1 
ATOM   12024 C CG  . LEU D 1 173 ? 37.842  80.056  1.849   1.00 33.06  ? 173 LEU D CG  1 
ATOM   12025 C CD1 . LEU D 1 173 ? 36.748  79.607  0.893   1.00 32.36  ? 173 LEU D CD1 1 
ATOM   12026 C CD2 . LEU D 1 173 ? 39.051  80.544  1.078   1.00 35.01  ? 173 LEU D CD2 1 
ATOM   12027 N N   . GLU D 1 174 ? 36.953  79.544  5.510   1.00 31.22  ? 174 GLU D N   1 
ATOM   12028 C CA  . GLU D 1 174 ? 37.154  78.293  6.229   1.00 29.37  ? 174 GLU D CA  1 
ATOM   12029 C C   . GLU D 1 174 ? 35.822  77.755  6.760   1.00 26.78  ? 174 GLU D C   1 
ATOM   12030 O O   . GLU D 1 174 ? 35.540  76.570  6.663   1.00 28.47  ? 174 GLU D O   1 
ATOM   12031 C CB  . GLU D 1 174 ? 38.211  78.548  7.306   1.00 30.38  ? 174 GLU D CB  1 
ATOM   12032 C CG  . GLU D 1 174 ? 38.735  77.272  7.958   1.00 30.52  ? 174 GLU D CG  1 
ATOM   12033 C CD  . GLU D 1 174 ? 39.480  76.402  6.976   1.00 37.58  ? 174 GLU D CD  1 
ATOM   12034 O OE1 . GLU D 1 174 ? 39.934  76.868  5.881   1.00 46.23  ? 174 GLU D OE1 1 
ATOM   12035 O OE2 . GLU D 1 174 ? 39.550  75.212  7.333   1.00 37.65  ? 174 GLU D OE2 1 
ATOM   12036 N N   . ASP D 1 175 ? 34.999  78.644  7.313   1.00 25.54  ? 175 ASP D N   1 
ATOM   12037 C CA  . ASP D 1 175 ? 33.684  78.312  7.827   1.00 23.29  ? 175 ASP D CA  1 
ATOM   12038 C C   . ASP D 1 175 ? 32.756  77.871  6.706   1.00 24.58  ? 175 ASP D C   1 
ATOM   12039 O O   . ASP D 1 175 ? 31.927  76.975  6.898   1.00 26.91  ? 175 ASP D O   1 
ATOM   12040 C CB  . ASP D 1 175 ? 33.093  79.494  8.580   1.00 23.36  ? 175 ASP D CB  1 
ATOM   12041 C CG  . ASP D 1 175 ? 33.521  79.650  10.042  1.00 21.99  ? 175 ASP D CG  1 
ATOM   12042 O OD1 . ASP D 1 175 ? 33.973  78.632  10.621  1.00 18.34  ? 175 ASP D OD1 1 
ATOM   12043 O OD2 . ASP D 1 175 ? 33.411  80.795  10.586  1.00 20.63  ? 175 ASP D OD2 1 
ATOM   12044 N N   . SER D 1 176 ? 32.878  78.526  5.547   1.00 25.80  ? 176 SER D N   1 
ATOM   12045 C CA  . SER D 1 176 ? 32.001  78.260  4.410   1.00 24.59  ? 176 SER D CA  1 
ATOM   12046 C C   . SER D 1 176 ? 32.282  76.870  3.825   1.00 24.60  ? 176 SER D C   1 
ATOM   12047 O O   . SER D 1 176 ? 31.350  76.167  3.457   1.00 24.74  ? 176 SER D O   1 
ATOM   12048 C CB  . SER D 1 176 ? 32.149  79.333  3.342   1.00 24.80  ? 176 SER D CB  1 
ATOM   12049 O OG  . SER D 1 176 ? 31.713  80.638  3.721   1.00 22.93  ? 176 SER D OG  1 
ATOM   12050 N N   . LEU D 1 177 ? 33.567  76.493  3.724   1.00 23.99  ? 177 LEU D N   1 
ATOM   12051 C CA  . LEU D 1 177 ? 33.984  75.159  3.324   1.00 23.36  ? 177 LEU D CA  1 
ATOM   12052 C C   . LEU D 1 177 ? 33.376  74.135  4.263   1.00 24.61  ? 177 LEU D C   1 
ATOM   12053 O O   . LEU D 1 177 ? 32.822  73.143  3.799   1.00 27.71  ? 177 LEU D O   1 
ATOM   12054 C CB  . LEU D 1 177 ? 35.505  75.003  3.308   1.00 25.45  ? 177 LEU D CB  1 
ATOM   12055 C CG  . LEU D 1 177 ? 36.259  75.795  2.233   1.00 24.34  ? 177 LEU D CG  1 
ATOM   12056 C CD1 . LEU D 1 177 ? 37.765  75.734  2.425   1.00 24.14  ? 177 LEU D CD1 1 
ATOM   12057 C CD2 . LEU D 1 177 ? 35.892  75.299  0.858   1.00 24.35  ? 177 LEU D CD2 1 
ATOM   12058 N N   . ASN D 1 178 ? 33.469  74.373  5.582   1.00 27.72  ? 178 ASN D N   1 
ATOM   12059 C CA  . ASN D 1 178 ? 32.956  73.435  6.580   1.00 26.11  ? 178 ASN D CA  1 
ATOM   12060 C C   . ASN D 1 178 ? 31.425  73.303  6.497   1.00 24.95  ? 178 ASN D C   1 
ATOM   12061 O O   . ASN D 1 178 ? 30.871  72.196  6.450   1.00 22.76  ? 178 ASN D O   1 
ATOM   12062 C CB  . ASN D 1 178 ? 33.445  73.808  7.973   1.00 27.65  ? 178 ASN D CB  1 
ATOM   12063 C CG  . ASN D 1 178 ? 34.936  73.582  8.187   1.00 29.08  ? 178 ASN D CG  1 
ATOM   12064 O OD1 . ASN D 1 178 ? 35.574  72.695  7.595   1.00 27.33  ? 178 ASN D OD1 1 
ATOM   12065 N ND2 . ASN D 1 178 ? 35.517  74.370  9.076   1.00 27.65  ? 178 ASN D ND2 1 
ATOM   12066 N N   . MET D 1 179 ? 30.737  74.449  6.451   1.00 24.63  ? 179 MET D N   1 
ATOM   12067 C CA  . MET D 1 179 ? 29.284  74.477  6.420   1.00 24.04  ? 179 MET D CA  1 
ATOM   12068 C C   . MET D 1 179 ? 28.751  73.883  5.129   1.00 23.82  ? 179 MET D C   1 
ATOM   12069 O O   . MET D 1 179 ? 27.840  73.072  5.176   1.00 25.93  ? 179 MET D O   1 
ATOM   12070 C CB  . MET D 1 179 ? 28.748  75.903  6.496   1.00 27.03  ? 179 MET D CB  1 
ATOM   12071 C CG  . MET D 1 179 ? 27.258  75.955  6.713   1.00 27.70  ? 179 MET D CG  1 
ATOM   12072 S SD  . MET D 1 179 ? 26.655  77.646  6.786   1.00 26.98  ? 179 MET D SD  1 
ATOM   12073 C CE  . MET D 1 179 ? 26.697  78.060  5.040   1.00 25.46  ? 179 MET D CE  1 
ATOM   12074 N N   . LEU D 1 180 ? 29.321  74.275  3.985   1.00 24.75  ? 180 LEU D N   1 
ATOM   12075 C CA  . LEU D 1 180 ? 28.870  73.752  2.701   1.00 25.38  ? 180 LEU D CA  1 
ATOM   12076 C C   . LEU D 1 180 ? 29.027  72.231  2.685   1.00 25.13  ? 180 LEU D C   1 
ATOM   12077 O O   . LEU D 1 180 ? 28.125  71.503  2.263   1.00 24.97  ? 180 LEU D O   1 
ATOM   12078 C CB  . LEU D 1 180 ? 29.586  74.394  1.511   1.00 27.61  ? 180 LEU D CB  1 
ATOM   12079 C CG  . LEU D 1 180 ? 29.268  75.862  1.211   1.00 27.68  ? 180 LEU D CG  1 
ATOM   12080 C CD1 . LEU D 1 180 ? 30.346  76.463  0.331   1.00 28.00  ? 180 LEU D CD1 1 
ATOM   12081 C CD2 . LEU D 1 180 ? 27.936  76.029  0.548   1.00 27.38  ? 180 LEU D CD2 1 
ATOM   12082 N N   . ALA D 1 181 ? 30.160  71.739  3.186   1.00 24.06  ? 181 ALA D N   1 
ATOM   12083 C CA  . ALA D 1 181 ? 30.332  70.301  3.282   1.00 24.98  ? 181 ALA D CA  1 
ATOM   12084 C C   . ALA D 1 181 ? 29.244  69.693  4.169   1.00 24.13  ? 181 ALA D C   1 
ATOM   12085 O O   . ALA D 1 181 ? 28.790  68.575  3.927   1.00 24.19  ? 181 ALA D O   1 
ATOM   12086 C CB  . ALA D 1 181 ? 31.718  69.992  3.793   1.00 26.96  ? 181 ALA D CB  1 
ATOM   12087 N N   . ALA D 1 182 ? 28.800  70.453  5.173   1.00 22.24  ? 182 ALA D N   1 
ATOM   12088 C CA  . ALA D 1 182 ? 27.874  69.921  6.155   1.00 23.87  ? 182 ALA D CA  1 
ATOM   12089 C C   . ALA D 1 182 ? 26.435  69.870  5.633   1.00 23.82  ? 182 ALA D C   1 
ATOM   12090 O O   . ALA D 1 182 ? 25.649  69.004  6.030   1.00 24.05  ? 182 ALA D O   1 
ATOM   12091 C CB  . ALA D 1 182 ? 27.979  70.759  7.422   1.00 24.80  ? 182 ALA D CB  1 
ATOM   12092 N N   . LEU D 1 183 ? 26.064  70.832  4.784   1.00 24.88  ? 183 LEU D N   1 
ATOM   12093 C CA  . LEU D 1 183 ? 24.658  71.001  4.472   1.00 25.41  ? 183 LEU D CA  1 
ATOM   12094 C C   . LEU D 1 183 ? 24.084  69.713  3.891   1.00 24.36  ? 183 LEU D C   1 
ATOM   12095 O O   . LEU D 1 183 ? 23.008  69.323  4.299   1.00 24.51  ? 183 LEU D O   1 
ATOM   12096 C CB  . LEU D 1 183 ? 24.407  72.170  3.535   1.00 25.98  ? 183 LEU D CB  1 
ATOM   12097 C CG  . LEU D 1 183 ? 24.745  73.553  4.071   1.00 26.83  ? 183 LEU D CG  1 
ATOM   12098 C CD1 . LEU D 1 183 ? 24.158  74.579  3.094   1.00 26.74  ? 183 LEU D CD1 1 
ATOM   12099 C CD2 . LEU D 1 183 ? 24.249  73.736  5.503   1.00 26.00  ? 183 LEU D CD2 1 
ATOM   12100 N N   . PRO D 1 184 ? 24.725  69.023  2.921   1.00 24.01  ? 184 PRO D N   1 
ATOM   12101 C CA  . PRO D 1 184 ? 24.166  67.796  2.373   1.00 24.15  ? 184 PRO D CA  1 
ATOM   12102 C C   . PRO D 1 184 ? 23.988  66.740  3.452   1.00 23.90  ? 184 PRO D C   1 
ATOM   12103 O O   . PRO D 1 184 ? 23.011  65.997  3.423   1.00 27.82  ? 184 PRO D O   1 
ATOM   12104 C CB  . PRO D 1 184 ? 25.140  67.328  1.288   1.00 25.85  ? 184 PRO D CB  1 
ATOM   12105 C CG  . PRO D 1 184 ? 26.040  68.500  1.015   1.00 26.34  ? 184 PRO D CG  1 
ATOM   12106 C CD  . PRO D 1 184 ? 25.957  69.412  2.229   1.00 27.19  ? 184 PRO D CD  1 
ATOM   12107 N N   . VAL D 1 185 ? 24.912  66.685  4.411   1.00 22.67  ? 185 VAL D N   1 
ATOM   12108 C CA  . VAL D 1 185 ? 24.780  65.721  5.491   1.00 21.75  ? 185 VAL D CA  1 
ATOM   12109 C C   . VAL D 1 185 ? 23.561  66.031  6.348   1.00 22.53  ? 185 VAL D C   1 
ATOM   12110 O O   . VAL D 1 185 ? 22.846  65.119  6.727   1.00 22.21  ? 185 VAL D O   1 
ATOM   12111 C CB  . VAL D 1 185 ? 26.027  65.607  6.372   1.00 21.99  ? 185 VAL D CB  1 
ATOM   12112 C CG1 . VAL D 1 185 ? 25.817  64.609  7.521   1.00 19.60  ? 185 VAL D CG1 1 
ATOM   12113 C CG2 . VAL D 1 185 ? 27.229  65.238  5.503   1.00 21.90  ? 185 VAL D CG2 1 
ATOM   12114 N N   . ILE D 1 186 ? 23.351  67.303  6.683   1.00 24.41  ? 186 ILE D N   1 
ATOM   12115 C CA  . ILE D 1 186 ? 22.258  67.691  7.565   1.00 25.64  ? 186 ILE D CA  1 
ATOM   12116 C C   . ILE D 1 186 ? 20.912  67.508  6.857   1.00 27.97  ? 186 ILE D C   1 
ATOM   12117 O O   . ILE D 1 186 ? 19.944  67.009  7.453   1.00 26.60  ? 186 ILE D O   1 
ATOM   12118 C CB  . ILE D 1 186 ? 22.457  69.144  8.019   1.00 25.75  ? 186 ILE D CB  1 
ATOM   12119 C CG1 . ILE D 1 186 ? 23.705  69.281  8.901   1.00 26.93  ? 186 ILE D CG1 1 
ATOM   12120 C CG2 . ILE D 1 186 ? 21.211  69.666  8.720   1.00 26.49  ? 186 ILE D CG2 1 
ATOM   12121 C CD1 . ILE D 1 186 ? 24.150  70.713  9.143   1.00 26.79  ? 186 ILE D CD1 1 
ATOM   12122 N N   . ALA D 1 187 ? 20.863  67.916  5.570   1.00 25.79  ? 187 ALA D N   1 
ATOM   12123 C CA  . ALA D 1 187 ? 19.670  67.798  4.758   1.00 21.80  ? 187 ALA D CA  1 
ATOM   12124 C C   . ALA D 1 187 ? 19.283  66.330  4.665   1.00 22.85  ? 187 ALA D C   1 
ATOM   12125 O O   . ALA D 1 187 ? 18.160  65.952  4.969   1.00 22.23  ? 187 ALA D O   1 
ATOM   12126 C CB  . ALA D 1 187 ? 19.903  68.402  3.397   1.00 22.63  ? 187 ALA D CB  1 
ATOM   12127 N N   . ALA D 1 188 ? 20.251  65.490  4.299   1.00 24.26  ? 188 ALA D N   1 
ATOM   12128 C CA  . ALA D 1 188 ? 19.939  64.081  4.137   1.00 24.46  ? 188 ALA D CA  1 
ATOM   12129 C C   . ALA D 1 188 ? 19.400  63.532  5.451   1.00 24.43  ? 188 ALA D C   1 
ATOM   12130 O O   . ALA D 1 188 ? 18.489  62.681  5.445   1.00 25.15  ? 188 ALA D O   1 
ATOM   12131 C CB  . ALA D 1 188 ? 21.117  63.270  3.617   1.00 23.03  ? 188 ALA D CB  1 
ATOM   12132 N N   . TYR D 1 189 ? 19.961  64.009  6.571   1.00 23.62  ? 189 TYR D N   1 
ATOM   12133 C CA  . TYR D 1 189 ? 19.623  63.397  7.846   1.00 24.87  ? 189 TYR D CA  1 
ATOM   12134 C C   . TYR D 1 189 ? 18.143  63.679  8.119   1.00 24.63  ? 189 TYR D C   1 
ATOM   12135 O O   . TYR D 1 189 ? 17.394  62.777  8.488   1.00 25.19  ? 189 TYR D O   1 
ATOM   12136 C CB  . TYR D 1 189 ? 20.560  63.883  8.955   1.00 25.90  ? 189 TYR D CB  1 
ATOM   12137 C CG  . TYR D 1 189 ? 20.338  63.166  10.282  1.00 25.32  ? 189 TYR D CG  1 
ATOM   12138 C CD1 . TYR D 1 189 ? 19.367  63.605  11.175  1.00 25.87  ? 189 TYR D CD1 1 
ATOM   12139 C CD2 . TYR D 1 189 ? 21.096  62.056  10.638  1.00 24.79  ? 189 TYR D CD2 1 
ATOM   12140 C CE1 . TYR D 1 189 ? 19.157  62.955  12.380  1.00 26.92  ? 189 TYR D CE1 1 
ATOM   12141 C CE2 . TYR D 1 189 ? 20.883  61.391  11.833  1.00 25.12  ? 189 TYR D CE2 1 
ATOM   12142 C CZ  . TYR D 1 189 ? 19.910  61.842  12.702  1.00 26.81  ? 189 TYR D CZ  1 
ATOM   12143 O OH  . TYR D 1 189 ? 19.682  61.198  13.873  1.00 33.07  ? 189 TYR D OH  1 
ATOM   12144 N N   . ILE D 1 190 ? 17.738  64.928  7.867   1.00 23.10  ? 190 ILE D N   1 
ATOM   12145 C CA  . ILE D 1 190 ? 16.360  65.369  8.006   1.00 23.53  ? 190 ILE D CA  1 
ATOM   12146 C C   . ILE D 1 190 ? 15.448  64.553  7.092   1.00 24.66  ? 190 ILE D C   1 
ATOM   12147 O O   . ILE D 1 190 ? 14.421  64.043  7.528   1.00 24.92  ? 190 ILE D O   1 
ATOM   12148 C CB  . ILE D 1 190 ? 16.277  66.875  7.718   1.00 23.46  ? 190 ILE D CB  1 
ATOM   12149 C CG1 . ILE D 1 190 ? 16.970  67.671  8.832   1.00 22.20  ? 190 ILE D CG1 1 
ATOM   12150 C CG2 . ILE D 1 190 ? 14.828  67.305  7.487   1.00 24.46  ? 190 ILE D CG2 1 
ATOM   12151 C CD1 . ILE D 1 190 ? 17.183  69.142  8.517   1.00 23.97  ? 190 ILE D CD1 1 
ATOM   12152 N N   . TYR D 1 191 ? 15.844  64.424  5.818   1.00 26.54  ? 191 TYR D N   1 
ATOM   12153 C CA  . TYR D 1 191 ? 15.071  63.674  4.848   1.00 25.99  ? 191 TYR D CA  1 
ATOM   12154 C C   . TYR D 1 191 ? 14.862  62.244  5.321   1.00 26.09  ? 191 TYR D C   1 
ATOM   12155 O O   . TYR D 1 191 ? 13.744  61.740  5.282   1.00 24.75  ? 191 TYR D O   1 
ATOM   12156 C CB  . TYR D 1 191 ? 15.786  63.676  3.500   1.00 28.46  ? 191 TYR D CB  1 
ATOM   12157 C CG  . TYR D 1 191 ? 14.981  63.059  2.367   1.00 28.77  ? 191 TYR D CG  1 
ATOM   12158 C CD1 . TYR D 1 191 ? 13.930  63.756  1.768   1.00 30.10  ? 191 TYR D CD1 1 
ATOM   12159 C CD2 . TYR D 1 191 ? 15.273  61.789  1.893   1.00 27.92  ? 191 TYR D CD2 1 
ATOM   12160 C CE1 . TYR D 1 191 ? 13.190  63.203  0.733   1.00 29.55  ? 191 TYR D CE1 1 
ATOM   12161 C CE2 . TYR D 1 191 ? 14.567  61.251  0.827   1.00 28.99  ? 191 TYR D CE2 1 
ATOM   12162 C CZ  . TYR D 1 191 ? 13.520  61.950  0.261   1.00 28.65  ? 191 TYR D CZ  1 
ATOM   12163 O OH  . TYR D 1 191 ? 12.826  61.386  -0.752  1.00 32.77  ? 191 TYR D OH  1 
ATOM   12164 N N   . ARG D 1 192 ? 15.957  61.603  5.737   1.00 27.38  ? 192 ARG D N   1 
ATOM   12165 C CA  . ARG D 1 192 ? 15.934  60.192  6.074   1.00 28.67  ? 192 ARG D CA  1 
ATOM   12166 C C   . ARG D 1 192 ? 15.165  59.975  7.373   1.00 30.69  ? 192 ARG D C   1 
ATOM   12167 O O   . ARG D 1 192 ? 14.495  58.956  7.514   1.00 33.92  ? 192 ARG D O   1 
ATOM   12168 C CB  . ARG D 1 192 ? 17.350  59.615  6.209   1.00 29.28  ? 192 ARG D CB  1 
ATOM   12169 C CG  . ARG D 1 192 ? 18.197  59.592  4.944   1.00 27.50  ? 192 ARG D CG  1 
ATOM   12170 C CD  . ARG D 1 192 ? 17.563  58.753  3.829   1.00 25.90  ? 192 ARG D CD  1 
ATOM   12171 N NE  . ARG D 1 192 ? 17.435  57.351  4.213   1.00 24.28  ? 192 ARG D NE  1 
ATOM   12172 C CZ  . ARG D 1 192 ? 17.071  56.376  3.380   1.00 25.68  ? 192 ARG D CZ  1 
ATOM   12173 N NH1 . ARG D 1 192 ? 16.872  56.644  2.101   1.00 25.37  ? 192 ARG D NH1 1 
ATOM   12174 N NH2 . ARG D 1 192 ? 16.966  55.125  3.815   1.00 23.05  ? 192 ARG D NH2 1 
ATOM   12175 N N   . ARG D 1 193 ? 15.245  60.928  8.310   1.00 28.80  ? 193 ARG D N   1 
ATOM   12176 C CA  . ARG D 1 193 ? 14.513  60.790  9.563   1.00 28.07  ? 193 ARG D CA  1 
ATOM   12177 C C   . ARG D 1 193 ? 13.014  61.028  9.335   1.00 25.42  ? 193 ARG D C   1 
ATOM   12178 O O   . ARG D 1 193 ? 12.182  60.263  9.829   1.00 26.13  ? 193 ARG D O   1 
ATOM   12179 C CB  . ARG D 1 193 ? 15.045  61.706  10.676  1.00 27.24  ? 193 ARG D CB  1 
ATOM   12180 C CG  . ARG D 1 193 ? 14.450  61.387  12.036  1.00 24.31  ? 193 ARG D CG  1 
ATOM   12181 C CD  . ARG D 1 193 ? 14.803  62.436  13.050  1.00 26.99  ? 193 ARG D CD  1 
ATOM   12182 N NE  . ARG D 1 193 ? 14.128  62.156  14.324  1.00 27.52  ? 193 ARG D NE  1 
ATOM   12183 C CZ  . ARG D 1 193 ? 13.582  63.074  15.105  1.00 25.99  ? 193 ARG D CZ  1 
ATOM   12184 N NH1 . ARG D 1 193 ? 13.712  64.360  14.822  1.00 24.59  ? 193 ARG D NH1 1 
ATOM   12185 N NH2 . ARG D 1 193 ? 12.954  62.686  16.199  1.00 24.93  ? 193 ARG D NH2 1 
ATOM   12186 N N   . LYS D 1 194 ? 12.659  62.076  8.579   1.00 25.02  ? 194 LYS D N   1 
ATOM   12187 C CA  . LYS D 1 194 ? 11.257  62.405  8.334   1.00 25.57  ? 194 LYS D CA  1 
ATOM   12188 C C   . LYS D 1 194 ? 10.525  61.367  7.475   1.00 26.43  ? 194 LYS D C   1 
ATOM   12189 O O   . LYS D 1 194 ? 9.383   61.003  7.763   1.00 28.86  ? 194 LYS D O   1 
ATOM   12190 C CB  . LYS D 1 194 ? 11.141  63.788  7.695   1.00 24.96  ? 194 LYS D CB  1 
ATOM   12191 C CG  . LYS D 1 194 ? 11.347  64.899  8.693   1.00 25.21  ? 194 LYS D CG  1 
ATOM   12192 C CD  . LYS D 1 194 ? 11.098  66.291  8.142   1.00 27.08  ? 194 LYS D CD  1 
ATOM   12193 C CE  . LYS D 1 194 ? 9.621   66.565  7.963   1.00 28.29  ? 194 LYS D CE  1 
ATOM   12194 N NZ  . LYS D 1 194 ? 8.951   66.912  9.216   1.00 28.31  ? 194 LYS D NZ  1 
ATOM   12195 N N   . TYR D 1 195 ? 11.161  60.898  6.400   1.00 24.98  ? 195 TYR D N   1 
ATOM   12196 C CA  . TYR D 1 195 ? 10.410  60.365  5.277   1.00 23.23  ? 195 TYR D CA  1 
ATOM   12197 C C   . TYR D 1 195 ? 10.818  58.939  4.921   1.00 23.70  ? 195 TYR D C   1 
ATOM   12198 O O   . TYR D 1 195 ? 10.072  58.271  4.213   1.00 29.41  ? 195 TYR D O   1 
ATOM   12199 C CB  . TYR D 1 195 ? 10.591  61.307  4.078   1.00 22.00  ? 195 TYR D CB  1 
ATOM   12200 C CG  . TYR D 1 195 ? 10.247  62.775  4.294   1.00 21.39  ? 195 TYR D CG  1 
ATOM   12201 C CD1 . TYR D 1 195 ? 8.950   63.181  4.555   1.00 24.93  ? 195 TYR D CD1 1 
ATOM   12202 C CD2 . TYR D 1 195 ? 11.208  63.765  4.175   1.00 21.96  ? 195 TYR D CD2 1 
ATOM   12203 C CE1 . TYR D 1 195 ? 8.624   64.524  4.732   1.00 27.61  ? 195 TYR D CE1 1 
ATOM   12204 C CE2 . TYR D 1 195 ? 10.903  65.106  4.334   1.00 21.80  ? 195 TYR D CE2 1 
ATOM   12205 C CZ  . TYR D 1 195 ? 9.612   65.488  4.627   1.00 25.07  ? 195 TYR D CZ  1 
ATOM   12206 O OH  . TYR D 1 195 ? 9.317   66.800  4.797   1.00 27.60  ? 195 TYR D OH  1 
ATOM   12207 N N   . LYS D 1 196 ? 11.990  58.482  5.366   1.00 25.24  ? 196 LYS D N   1 
ATOM   12208 C CA  . LYS D 1 196 ? 12.515  57.181  4.976   1.00 25.84  ? 196 LYS D CA  1 
ATOM   12209 C C   . LYS D 1 196 ? 12.871  56.353  6.216   1.00 27.01  ? 196 LYS D C   1 
ATOM   12210 O O   . LYS D 1 196 ? 13.889  55.657  6.238   1.00 26.34  ? 196 LYS D O   1 
ATOM   12211 C CB  . LYS D 1 196 ? 13.751  57.375  4.083   1.00 27.76  ? 196 LYS D CB  1 
ATOM   12212 C CG  . LYS D 1 196 ? 13.543  58.141  2.773   1.00 26.10  ? 196 LYS D CG  1 
ATOM   12213 C CD  . LYS D 1 196 ? 12.634  57.408  1.786   1.00 24.93  ? 196 LYS D CD  1 
ATOM   12214 C CE  . LYS D 1 196 ? 12.209  58.363  0.697   1.00 24.54  ? 196 LYS D CE  1 
ATOM   12215 N NZ  . LYS D 1 196 ? 11.138  57.858  -0.163  1.00 22.68  ? 196 LYS D NZ  1 
ATOM   12216 N N   . GLY D 1 197 ? 12.045  56.440  7.271   1.00 27.41  ? 197 GLY D N   1 
ATOM   12217 C CA  . GLY D 1 197 ? 12.098  55.451  8.339   1.00 27.44  ? 197 GLY D CA  1 
ATOM   12218 C C   . GLY D 1 197 ? 13.407  55.453  9.122   1.00 25.88  ? 197 GLY D C   1 
ATOM   12219 O O   . GLY D 1 197 ? 13.743  54.437  9.703   1.00 25.35  ? 197 GLY D O   1 
ATOM   12220 N N   . ASP D 1 198 ? 14.121  56.588  9.131   1.00 25.08  ? 198 ASP D N   1 
ATOM   12221 C CA  . ASP D 1 198 ? 15.168  56.863  10.099  1.00 29.08  ? 198 ASP D CA  1 
ATOM   12222 C C   . ASP D 1 198 ? 16.335  55.876  9.963   1.00 30.15  ? 198 ASP D C   1 
ATOM   12223 O O   . ASP D 1 198 ? 16.986  55.555  10.959  1.00 27.40  ? 198 ASP D O   1 
ATOM   12224 C CB  . ASP D 1 198 ? 14.603  56.895  11.518  1.00 29.13  ? 198 ASP D CB  1 
ATOM   12225 C CG  . ASP D 1 198 ? 15.447  57.623  12.558  1.00 28.95  ? 198 ASP D CG  1 
ATOM   12226 O OD1 . ASP D 1 198 ? 16.362  58.372  12.145  1.00 32.36  ? 198 ASP D OD1 1 
ATOM   12227 O OD2 . ASP D 1 198 ? 15.203  57.428  13.771  1.00 25.99  ? 198 ASP D OD2 1 
ATOM   12228 N N   . THR D 1 199 ? 16.601  55.417  8.729   1.00 30.04  ? 199 THR D N   1 
ATOM   12229 C CA  . THR D 1 199 ? 17.843  54.732  8.378   1.00 29.03  ? 199 THR D CA  1 
ATOM   12230 C C   . THR D 1 199 ? 18.759  55.688  7.614   1.00 30.59  ? 199 THR D C   1 
ATOM   12231 O O   . THR D 1 199 ? 18.313  56.509  6.803   1.00 31.29  ? 199 THR D O   1 
ATOM   12232 C CB  . THR D 1 199 ? 17.511  53.494  7.554   1.00 29.65  ? 199 THR D CB  1 
ATOM   12233 O OG1 . THR D 1 199 ? 16.739  53.862  6.412   1.00 28.28  ? 199 THR D OG1 1 
ATOM   12234 C CG2 . THR D 1 199 ? 16.702  52.496  8.362   1.00 31.49  ? 199 THR D CG2 1 
ATOM   12235 N N   . HIS D 1 200 ? 20.058  55.595  7.895   1.00 30.65  ? 200 HIS D N   1 
ATOM   12236 C CA  . HIS D 1 200 ? 20.984  56.675  7.578   1.00 30.16  ? 200 HIS D CA  1 
ATOM   12237 C C   . HIS D 1 200 ? 22.114  56.136  6.707   1.00 30.37  ? 200 HIS D C   1 
ATOM   12238 O O   . HIS D 1 200 ? 22.662  55.083  7.007   1.00 28.56  ? 200 HIS D O   1 
ATOM   12239 C CB  . HIS D 1 200 ? 21.439  57.368  8.871   1.00 27.39  ? 200 HIS D CB  1 
ATOM   12240 C CG  . HIS D 1 200 ? 20.299  58.032  9.552   1.00 25.78  ? 200 HIS D CG  1 
ATOM   12241 N ND1 . HIS D 1 200 ? 19.870  59.299  9.225   1.00 27.07  ? 200 HIS D ND1 1 
ATOM   12242 C CD2 . HIS D 1 200 ? 19.420  57.572  10.470  1.00 27.00  ? 200 HIS D CD2 1 
ATOM   12243 C CE1 . HIS D 1 200 ? 18.793  59.599  9.952   1.00 25.72  ? 200 HIS D CE1 1 
ATOM   12244 N NE2 . HIS D 1 200 ? 18.504  58.563  10.727  1.00 24.79  ? 200 HIS D NE2 1 
ATOM   12245 N N   . ILE D 1 201 ? 22.423  56.878  5.627   1.00 33.35  ? 201 ILE D N   1 
ATOM   12246 C CA  . ILE D 1 201 ? 23.328  56.471  4.560   1.00 32.05  ? 201 ILE D CA  1 
ATOM   12247 C C   . ILE D 1 201 ? 24.493  57.458  4.551   1.00 36.47  ? 201 ILE D C   1 
ATOM   12248 O O   . ILE D 1 201 ? 24.258  58.666  4.476   1.00 34.44  ? 201 ILE D O   1 
ATOM   12249 C CB  . ILE D 1 201 ? 22.605  56.461  3.200   1.00 30.84  ? 201 ILE D CB  1 
ATOM   12250 C CG1 . ILE D 1 201 ? 21.550  55.365  3.115   1.00 31.20  ? 201 ILE D CG1 1 
ATOM   12251 C CG2 . ILE D 1 201 ? 23.602  56.333  2.055   1.00 32.25  ? 201 ILE D CG2 1 
ATOM   12252 C CD1 . ILE D 1 201 ? 20.502  55.579  2.039   1.00 30.14  ? 201 ILE D CD1 1 
ATOM   12253 N N   . ALA D 1 202 ? 25.728  56.926  4.654   1.00 37.43  ? 202 ALA D N   1 
ATOM   12254 C CA  . ALA D 1 202 ? 26.944  57.726  4.755   1.00 38.08  ? 202 ALA D CA  1 
ATOM   12255 C C   . ALA D 1 202 ? 27.313  58.358  3.410   1.00 39.21  ? 202 ALA D C   1 
ATOM   12256 O O   . ALA D 1 202 ? 26.923  57.864  2.347   1.00 32.32  ? 202 ALA D O   1 
ATOM   12257 C CB  . ALA D 1 202 ? 28.087  56.847  5.222   1.00 35.06  ? 202 ALA D CB  1 
ATOM   12258 N N   . PRO D 1 203 ? 28.164  59.408  3.422   1.00 36.43  ? 203 PRO D N   1 
ATOM   12259 C CA  . PRO D 1 203 ? 28.739  59.948  2.192   1.00 36.17  ? 203 PRO D CA  1 
ATOM   12260 C C   . PRO D 1 203 ? 29.486  58.834  1.475   1.00 37.07  ? 203 PRO D C   1 
ATOM   12261 O O   . PRO D 1 203 ? 30.109  57.980  2.105   1.00 42.29  ? 203 PRO D O   1 
ATOM   12262 C CB  . PRO D 1 203 ? 29.683  61.051  2.639   1.00 37.14  ? 203 PRO D CB  1 
ATOM   12263 C CG  . PRO D 1 203 ? 29.218  61.389  4.045   1.00 38.56  ? 203 PRO D CG  1 
ATOM   12264 C CD  . PRO D 1 203 ? 28.671  60.079  4.625   1.00 36.67  ? 203 PRO D CD  1 
ATOM   12265 N N   . ASP D 1 204 ? 29.357  58.814  0.152   1.00 39.94  ? 204 ASP D N   1 
ATOM   12266 C CA  . ASP D 1 204 ? 30.210  57.994  -0.677  1.00 46.45  ? 204 ASP D CA  1 
ATOM   12267 C C   . ASP D 1 204 ? 31.401  58.863  -1.050  1.00 55.22  ? 204 ASP D C   1 
ATOM   12268 O O   . ASP D 1 204 ? 31.202  59.945  -1.577  1.00 51.31  ? 204 ASP D O   1 
ATOM   12269 C CB  . ASP D 1 204 ? 29.498  57.509  -1.918  1.00 45.70  ? 204 ASP D CB  1 
ATOM   12270 C CG  . ASP D 1 204 ? 30.382  56.708  -2.854  1.00 48.87  ? 204 ASP D CG  1 
ATOM   12271 O OD1 . ASP D 1 204 ? 31.470  57.221  -3.196  1.00 55.26  ? 204 ASP D OD1 1 
ATOM   12272 O OD2 . ASP D 1 204 ? 29.978  55.586  -3.207  1.00 47.41  ? 204 ASP D OD2 1 
ATOM   12273 N N   . PRO D 1 205 ? 32.657  58.434  -0.806  1.00 64.62  ? 205 PRO D N   1 
ATOM   12274 C CA  . PRO D 1 205 ? 33.794  59.354  -0.876  1.00 67.30  ? 205 PRO D CA  1 
ATOM   12275 C C   . PRO D 1 205 ? 34.294  59.616  -2.298  1.00 53.82  ? 205 PRO D C   1 
ATOM   12276 O O   . PRO D 1 205 ? 35.208  60.416  -2.475  1.00 42.16  ? 205 PRO D O   1 
ATOM   12277 C CB  . PRO D 1 205 ? 34.816  58.600  -0.016  1.00 72.25  ? 205 PRO D CB  1 
ATOM   12278 C CG  . PRO D 1 205 ? 34.586  57.150  -0.420  1.00 71.68  ? 205 PRO D CG  1 
ATOM   12279 C CD  . PRO D 1 205 ? 33.069  57.045  -0.543  1.00 68.11  ? 205 PRO D CD  1 
ATOM   12280 N N   . ASN D 1 206 ? 33.680  58.958  -3.294  1.00 46.85  ? 206 ASN D N   1 
ATOM   12281 C CA  . ASN D 1 206 ? 34.022  59.195  -4.682  1.00 51.10  ? 206 ASN D CA  1 
ATOM   12282 C C   . ASN D 1 206 ? 32.842  59.824  -5.441  1.00 47.71  ? 206 ASN D C   1 
ATOM   12283 O O   . ASN D 1 206 ? 32.743  59.673  -6.653  1.00 52.04  ? 206 ASN D O   1 
ATOM   12284 C CB  . ASN D 1 206 ? 34.607  57.923  -5.303  1.00 65.18  ? 206 ASN D CB  1 
ATOM   12285 C CG  . ASN D 1 206 ? 33.601  56.824  -5.593  1.00 71.33  ? 206 ASN D CG  1 
ATOM   12286 O OD1 . ASN D 1 206 ? 32.548  57.066  -6.199  1.00 79.78  ? 206 ASN D OD1 1 
ATOM   12287 N ND2 . ASN D 1 206 ? 33.917  55.595  -5.208  1.00 69.05  ? 206 ASN D ND2 1 
ATOM   12288 N N   . LEU D 1 207 ? 31.960  60.561  -4.748  1.00 41.04  ? 207 LEU D N   1 
ATOM   12289 C CA  . LEU D 1 207 ? 30.865  61.294  -5.375  1.00 34.68  ? 207 LEU D CA  1 
ATOM   12290 C C   . LEU D 1 207 ? 31.095  62.789  -5.185  1.00 30.38  ? 207 LEU D C   1 
ATOM   12291 O O   . LEU D 1 207 ? 31.538  63.216  -4.126  1.00 35.27  ? 207 LEU D O   1 
ATOM   12292 C CB  . LEU D 1 207 ? 29.491  60.911  -4.810  1.00 34.00  ? 207 LEU D CB  1 
ATOM   12293 C CG  . LEU D 1 207 ? 28.890  59.559  -5.214  1.00 35.90  ? 207 LEU D CG  1 
ATOM   12294 C CD1 . LEU D 1 207 ? 27.477  59.461  -4.679  1.00 34.60  ? 207 LEU D CD1 1 
ATOM   12295 C CD2 . LEU D 1 207 ? 28.869  59.320  -6.723  1.00 39.55  ? 207 LEU D CD2 1 
ATOM   12296 N N   . ASP D 1 208 ? 30.727  63.592  -6.181  1.00 26.59  ? 208 ASP D N   1 
ATOM   12297 C CA  . ASP D 1 208 ? 30.678  65.032  -5.992  1.00 26.40  ? 208 ASP D CA  1 
ATOM   12298 C C   . ASP D 1 208 ? 29.546  65.414  -5.038  1.00 26.73  ? 208 ASP D C   1 
ATOM   12299 O O   . ASP D 1 208 ? 28.664  64.611  -4.742  1.00 27.54  ? 208 ASP D O   1 
ATOM   12300 C CB  . ASP D 1 208 ? 30.485  65.744  -7.323  1.00 26.41  ? 208 ASP D CB  1 
ATOM   12301 C CG  . ASP D 1 208 ? 29.341  65.180  -8.142  1.00 26.87  ? 208 ASP D CG  1 
ATOM   12302 O OD1 . ASP D 1 208 ? 29.568  64.086  -8.709  1.00 27.47  ? 208 ASP D OD1 1 
ATOM   12303 O OD2 . ASP D 1 208 ? 28.229  65.805  -8.135  1.00 25.68  ? 208 ASP D OD2 1 
ATOM   12304 N N   . TRP D 1 209 ? 29.542  66.692  -4.639  1.00 26.81  ? 209 TRP D N   1 
ATOM   12305 C CA  . TRP D 1 209 ? 28.683  67.237  -3.593  1.00 26.42  ? 209 TRP D CA  1 
ATOM   12306 C C   . TRP D 1 209 ? 27.198  66.971  -3.871  1.00 28.96  ? 209 TRP D C   1 
ATOM   12307 O O   . TRP D 1 209 ? 26.473  66.445  -3.019  1.00 30.53  ? 209 TRP D O   1 
ATOM   12308 C CB  . TRP D 1 209 ? 29.013  68.727  -3.535  1.00 25.44  ? 209 TRP D CB  1 
ATOM   12309 C CG  . TRP D 1 209 ? 28.408  69.579  -2.461  1.00 24.58  ? 209 TRP D CG  1 
ATOM   12310 C CD1 . TRP D 1 209 ? 28.785  69.647  -1.157  1.00 25.15  ? 209 TRP D CD1 1 
ATOM   12311 C CD2 . TRP D 1 209 ? 27.469  70.650  -2.656  1.00 24.19  ? 209 TRP D CD2 1 
ATOM   12312 N NE1 . TRP D 1 209 ? 28.080  70.617  -0.502  1.00 23.81  ? 209 TRP D NE1 1 
ATOM   12313 C CE2 . TRP D 1 209 ? 27.276  71.264  -1.396  1.00 24.19  ? 209 TRP D CE2 1 
ATOM   12314 C CE3 . TRP D 1 209 ? 26.742  71.117  -3.753  1.00 24.10  ? 209 TRP D CE3 1 
ATOM   12315 C CZ2 . TRP D 1 209 ? 26.394  72.328  -1.201  1.00 23.01  ? 209 TRP D CZ2 1 
ATOM   12316 C CZ3 . TRP D 1 209 ? 25.883  72.188  -3.567  1.00 25.41  ? 209 TRP D CZ3 1 
ATOM   12317 C CH2 . TRP D 1 209 ? 25.728  72.794  -2.311  1.00 24.67  ? 209 TRP D CH2 1 
ATOM   12318 N N   . SER D 1 210 ? 26.758  67.291  -5.091  1.00 27.54  ? 210 SER D N   1 
ATOM   12319 C CA  . SER D 1 210 ? 25.349  67.211  -5.444  1.00 26.56  ? 210 SER D CA  1 
ATOM   12320 C C   . SER D 1 210 ? 24.893  65.761  -5.413  1.00 25.73  ? 210 SER D C   1 
ATOM   12321 O O   . SER D 1 210 ? 23.809  65.419  -4.931  1.00 25.78  ? 210 SER D O   1 
ATOM   12322 C CB  . SER D 1 210 ? 25.111  67.803  -6.807  1.00 25.77  ? 210 SER D CB  1 
ATOM   12323 O OG  . SER D 1 210 ? 25.516  69.163  -6.816  1.00 27.13  ? 210 SER D OG  1 
ATOM   12324 N N   . ALA D 1 211 ? 25.732  64.914  -5.993  1.00 26.81  ? 211 ALA D N   1 
ATOM   12325 C CA  . ALA D 1 211 ? 25.389  63.518  -6.114  1.00 29.83  ? 211 ALA D CA  1 
ATOM   12326 C C   . ALA D 1 211 ? 25.498  62.844  -4.746  1.00 26.78  ? 211 ALA D C   1 
ATOM   12327 O O   . ALA D 1 211 ? 24.850  61.837  -4.495  1.00 30.10  ? 211 ALA D O   1 
ATOM   12328 C CB  . ALA D 1 211 ? 26.260  62.903  -7.173  1.00 33.86  ? 211 ALA D CB  1 
ATOM   12329 N N   . ASN D 1 212 ? 26.278  63.418  -3.834  1.00 25.31  ? 212 ASN D N   1 
ATOM   12330 C CA  . ASN D 1 212 ? 26.324  62.850  -2.503  1.00 26.32  ? 212 ASN D CA  1 
ATOM   12331 C C   . ASN D 1 212 ? 25.008  63.114  -1.771  1.00 25.85  ? 212 ASN D C   1 
ATOM   12332 O O   . ASN D 1 212 ? 24.568  62.264  -0.988  1.00 24.22  ? 212 ASN D O   1 
ATOM   12333 C CB  . ASN D 1 212 ? 27.543  63.286  -1.701  1.00 28.83  ? 212 ASN D CB  1 
ATOM   12334 C CG  . ASN D 1 212 ? 28.484  62.131  -1.437  1.00 29.92  ? 212 ASN D CG  1 
ATOM   12335 O OD1 . ASN D 1 212 ? 28.065  60.981  -1.260  1.00 28.22  ? 212 ASN D OD1 1 
ATOM   12336 N ND2 . ASN D 1 212 ? 29.772  62.422  -1.404  1.00 34.27  ? 212 ASN D ND2 1 
ATOM   12337 N N   . LEU D 1 213 ? 24.395  64.285  -2.020  1.00 23.05  ? 213 LEU D N   1 
ATOM   12338 C CA  . LEU D 1 213 ? 23.101  64.579  -1.436  1.00 21.51  ? 213 LEU D CA  1 
ATOM   12339 C C   . LEU D 1 213 ? 22.100  63.541  -1.910  1.00 20.91  ? 213 LEU D C   1 
ATOM   12340 O O   . LEU D 1 213 ? 21.414  62.928  -1.103  1.00 22.39  ? 213 LEU D O   1 
ATOM   12341 C CB  . LEU D 1 213 ? 22.591  65.978  -1.730  1.00 21.04  ? 213 LEU D CB  1 
ATOM   12342 C CG  . LEU D 1 213 ? 21.273  66.346  -1.040  1.00 21.63  ? 213 LEU D CG  1 
ATOM   12343 C CD1 . LEU D 1 213 ? 21.298  65.967  0.429   1.00 21.15  ? 213 LEU D CD1 1 
ATOM   12344 C CD2 . LEU D 1 213 ? 21.007  67.846  -1.173  1.00 21.99  ? 213 LEU D CD2 1 
ATOM   12345 N N   . ALA D 1 214 ? 22.053  63.316  -3.219  1.00 22.87  ? 214 ALA D N   1 
ATOM   12346 C CA  . ALA D 1 214 ? 21.165  62.293  -3.758  1.00 24.73  ? 214 ALA D CA  1 
ATOM   12347 C C   . ALA D 1 214 ? 21.453  60.936  -3.111  1.00 24.99  ? 214 ALA D C   1 
ATOM   12348 O O   . ALA D 1 214 ? 20.543  60.234  -2.677  1.00 26.56  ? 214 ALA D O   1 
ATOM   12349 C CB  . ALA D 1 214 ? 21.305  62.215  -5.269  1.00 25.06  ? 214 ALA D CB  1 
ATOM   12350 N N   . HIS D 1 215 ? 22.725  60.536  -3.097  1.00 26.03  ? 215 HIS D N   1 
ATOM   12351 C CA  . HIS D 1 215 ? 23.102  59.247  -2.534  1.00 28.12  ? 215 HIS D CA  1 
ATOM   12352 C C   . HIS D 1 215 ? 22.618  59.087  -1.093  1.00 27.33  ? 215 HIS D C   1 
ATOM   12353 O O   . HIS D 1 215 ? 22.101  58.034  -0.713  1.00 21.66  ? 215 HIS D O   1 
ATOM   12354 C CB  . HIS D 1 215 ? 24.622  59.099  -2.562  1.00 29.13  ? 215 HIS D CB  1 
ATOM   12355 C CG  . HIS D 1 215 ? 25.113  57.851  -1.917  1.00 27.38  ? 215 HIS D CG  1 
ATOM   12356 N ND1 . HIS D 1 215 ? 24.889  56.602  -2.449  1.00 27.45  ? 215 HIS D ND1 1 
ATOM   12357 C CD2 . HIS D 1 215 ? 25.817  57.676  -0.804  1.00 24.59  ? 215 HIS D CD2 1 
ATOM   12358 C CE1 . HIS D 1 215 ? 25.458  55.700  -1.664  1.00 28.12  ? 215 HIS D CE1 1 
ATOM   12359 N NE2 . HIS D 1 215 ? 26.040  56.339  -0.667  1.00 25.52  ? 215 HIS D NE2 1 
ATOM   12360 N N   . MET D 1 216 ? 22.843  60.128  -0.279  1.00 28.01  ? 216 MET D N   1 
ATOM   12361 C CA  . MET D 1 216 ? 22.570  60.010  1.143   1.00 30.27  ? 216 MET D CA  1 
ATOM   12362 C C   . MET D 1 216 ? 21.054  60.077  1.374   1.00 33.45  ? 216 MET D C   1 
ATOM   12363 O O   . MET D 1 216 ? 20.557  59.571  2.397   1.00 29.77  ? 216 MET D O   1 
ATOM   12364 C CB  . MET D 1 216 ? 23.344  61.064  1.940   1.00 28.61  ? 216 MET D CB  1 
ATOM   12365 C CG  . MET D 1 216 ? 24.862  60.882  1.913   1.00 28.39  ? 216 MET D CG  1 
ATOM   12366 S SD  . MET D 1 216 ? 25.659  62.119  2.961   1.00 30.13  ? 216 MET D SD  1 
ATOM   12367 C CE  . MET D 1 216 ? 25.089  63.703  2.330   1.00 28.95  ? 216 MET D CE  1 
ATOM   12368 N N   . MET D 1 217 ? 20.330  60.673  0.400   1.00 30.12  ? 217 MET D N   1 
ATOM   12369 C CA  . MET D 1 217 ? 18.882  60.755  0.473   1.00 27.87  ? 217 MET D CA  1 
ATOM   12370 C C   . MET D 1 217 ? 18.273  59.440  0.034   1.00 25.80  ? 217 MET D C   1 
ATOM   12371 O O   . MET D 1 217 ? 17.103  59.199  0.300   1.00 25.68  ? 217 MET D O   1 
ATOM   12372 C CB  . MET D 1 217 ? 18.316  61.854  -0.417  1.00 28.84  ? 217 MET D CB  1 
ATOM   12373 C CG  . MET D 1 217 ? 18.337  63.207  0.228   1.00 32.82  ? 217 MET D CG  1 
ATOM   12374 S SD  . MET D 1 217 ? 18.020  64.478  -1.006  1.00 31.68  ? 217 MET D SD  1 
ATOM   12375 C CE  . MET D 1 217 ? 16.256  64.203  -1.231  1.00 30.14  ? 217 MET D CE  1 
ATOM   12376 N N   . GLY D 1 218 ? 19.066  58.630  -0.671  1.00 27.53  ? 218 GLY D N   1 
ATOM   12377 C CA  . GLY D 1 218 ? 18.656  57.290  -1.087  1.00 27.78  ? 218 GLY D CA  1 
ATOM   12378 C C   . GLY D 1 218 ? 18.521  57.116  -2.601  1.00 28.62  ? 218 GLY D C   1 
ATOM   12379 O O   . GLY D 1 218 ? 17.993  56.111  -3.057  1.00 27.27  ? 218 GLY D O   1 
ATOM   12380 N N   . PHE D 1 219 ? 18.977  58.079  -3.406  1.00 32.52  ? 219 PHE D N   1 
ATOM   12381 C CA  . PHE D 1 219 ? 18.751  57.983  -4.845  1.00 33.20  ? 219 PHE D CA  1 
ATOM   12382 C C   . PHE D 1 219 ? 20.098  57.863  -5.549  1.00 34.78  ? 219 PHE D C   1 
ATOM   12383 O O   . PHE D 1 219 ? 20.843  58.837  -5.636  1.00 36.05  ? 219 PHE D O   1 
ATOM   12384 C CB  . PHE D 1 219 ? 17.965  59.167  -5.421  1.00 33.17  ? 219 PHE D CB  1 
ATOM   12385 C CG  . PHE D 1 219 ? 16.598  59.391  -4.792  1.00 30.87  ? 219 PHE D CG  1 
ATOM   12386 C CD1 . PHE D 1 219 ? 16.482  59.996  -3.549  1.00 31.39  ? 219 PHE D CD1 1 
ATOM   12387 C CD2 . PHE D 1 219 ? 15.440  59.020  -5.453  1.00 30.22  ? 219 PHE D CD2 1 
ATOM   12388 C CE1 . PHE D 1 219 ? 15.239  60.234  -2.989  1.00 29.74  ? 219 PHE D CE1 1 
ATOM   12389 C CE2 . PHE D 1 219 ? 14.208  59.217  -4.870  1.00 31.56  ? 219 PHE D CE2 1 
ATOM   12390 C CZ  . PHE D 1 219 ? 14.110  59.822  -3.644  1.00 31.59  ? 219 PHE D CZ  1 
ATOM   12391 N N   . ASP D 1 220 ? 20.375  56.663  -6.075  1.00 35.16  ? 220 ASP D N   1 
ATOM   12392 C CA  . ASP D 1 220 ? 21.615  56.374  -6.763  1.00 34.11  ? 220 ASP D CA  1 
ATOM   12393 C C   . ASP D 1 220 ? 21.318  56.120  -8.232  1.00 37.31  ? 220 ASP D C   1 
ATOM   12394 O O   . ASP D 1 220 ? 21.097  54.987  -8.638  1.00 38.13  ? 220 ASP D O   1 
ATOM   12395 C CB  . ASP D 1 220 ? 22.307  55.186  -6.134  1.00 31.34  ? 220 ASP D CB  1 
ATOM   12396 C CG  . ASP D 1 220 ? 22.963  55.506  -4.812  1.00 31.92  ? 220 ASP D CG  1 
ATOM   12397 O OD1 . ASP D 1 220 ? 23.627  56.575  -4.726  1.00 32.74  ? 220 ASP D OD1 1 
ATOM   12398 O OD2 . ASP D 1 220 ? 22.796  54.691  -3.897  1.00 32.33  ? 220 ASP D OD2 1 
ATOM   12399 N N   . ASP D 1 221 ? 21.358  57.181  -9.030  1.00 38.34  ? 221 ASP D N   1 
ATOM   12400 C CA  . ASP D 1 221 ? 20.917  57.066  -10.402 1.00 38.11  ? 221 ASP D CA  1 
ATOM   12401 C C   . ASP D 1 221 ? 21.545  58.190  -11.201 1.00 32.01  ? 221 ASP D C   1 
ATOM   12402 O O   . ASP D 1 221 ? 21.539  59.335  -10.782 1.00 27.02  ? 221 ASP D O   1 
ATOM   12403 C CB  . ASP D 1 221 ? 19.399  57.047  -10.441 1.00 43.69  ? 221 ASP D CB  1 
ATOM   12404 C CG  . ASP D 1 221 ? 18.787  56.859  -11.814 1.00 46.33  ? 221 ASP D CG  1 
ATOM   12405 O OD1 . ASP D 1 221 ? 18.924  57.774  -12.656 1.00 47.16  ? 221 ASP D OD1 1 
ATOM   12406 O OD2 . ASP D 1 221 ? 18.190  55.794  -12.011 1.00 58.66  ? 221 ASP D OD2 1 
ATOM   12407 N N   . PHE D 1 222 ? 22.075  57.856  -12.372 1.00 33.42  ? 222 PHE D N   1 
ATOM   12408 C CA  . PHE D 1 222 ? 22.816  58.849  -13.124 1.00 37.70  ? 222 PHE D CA  1 
ATOM   12409 C C   . PHE D 1 222 ? 21.961  60.082  -13.423 1.00 29.12  ? 222 PHE D C   1 
ATOM   12410 O O   . PHE D 1 222 ? 22.406  61.212  -13.266 1.00 28.33  ? 222 PHE D O   1 
ATOM   12411 C CB  . PHE D 1 222 ? 23.344  58.216  -14.411 1.00 48.23  ? 222 PHE D CB  1 
ATOM   12412 C CG  . PHE D 1 222 ? 24.083  59.235  -15.263 1.00 51.75  ? 222 PHE D CG  1 
ATOM   12413 C CD1 . PHE D 1 222 ? 25.316  59.734  -14.848 1.00 49.54  ? 222 PHE D CD1 1 
ATOM   12414 C CD2 . PHE D 1 222 ? 23.509  59.724  -16.438 1.00 53.30  ? 222 PHE D CD2 1 
ATOM   12415 C CE1 . PHE D 1 222 ? 25.973  60.678  -15.609 1.00 47.64  ? 222 PHE D CE1 1 
ATOM   12416 C CE2 . PHE D 1 222 ? 24.161  60.688  -17.182 1.00 51.62  ? 222 PHE D CE2 1 
ATOM   12417 C CZ  . PHE D 1 222 ? 25.388  61.157  -16.767 1.00 51.34  ? 222 PHE D CZ  1 
ATOM   12418 N N   . GLU D 1 223 ? 20.748  59.866  -13.904 1.00 26.57  ? 223 GLU D N   1 
ATOM   12419 C CA  . GLU D 1 223 ? 19.874  60.970  -14.263 1.00 31.20  ? 223 GLU D CA  1 
ATOM   12420 C C   . GLU D 1 223 ? 19.616  61.831  -13.023 1.00 30.11  ? 223 GLU D C   1 
ATOM   12421 O O   . GLU D 1 223 ? 19.567  63.058  -13.155 1.00 26.93  ? 223 GLU D O   1 
ATOM   12422 C CB  . GLU D 1 223 ? 18.554  60.505  -14.908 1.00 36.61  ? 223 GLU D CB  1 
ATOM   12423 C CG  . GLU D 1 223 ? 18.641  60.043  -16.366 1.00 38.05  ? 223 GLU D CG  1 
ATOM   12424 C CD  . GLU D 1 223 ? 17.318  59.768  -17.087 1.00 45.16  ? 223 GLU D CD  1 
ATOM   12425 O OE1 . GLU D 1 223 ? 17.394  58.943  -18.026 1.00 50.33  ? 223 GLU D OE1 1 
ATOM   12426 O OE2 . GLU D 1 223 ? 16.231  60.336  -16.785 1.00 38.41  ? 223 GLU D OE2 1 
ATOM   12427 N N   . VAL D 1 224 ? 19.464  61.178  -11.843 1.00 26.06  ? 224 VAL D N   1 
ATOM   12428 C CA  . VAL D 1 224 ? 19.163  61.869  -10.601 1.00 24.91  ? 224 VAL D CA  1 
ATOM   12429 C C   . VAL D 1 224 ? 20.377  62.713  -10.222 1.00 25.23  ? 224 VAL D C   1 
ATOM   12430 O O   . VAL D 1 224 ? 20.236  63.866  -9.836  1.00 24.50  ? 224 VAL D O   1 
ATOM   12431 C CB  . VAL D 1 224 ? 18.742  60.937  -9.440  1.00 26.72  ? 224 VAL D CB  1 
ATOM   12432 C CG1 . VAL D 1 224 ? 18.551  61.670  -8.099  1.00 25.14  ? 224 VAL D CG1 1 
ATOM   12433 C CG2 . VAL D 1 224 ? 17.465  60.168  -9.766  1.00 28.28  ? 224 VAL D CG2 1 
ATOM   12434 N N   . TYR D 1 225 ? 21.569  62.122  -10.306 1.00 26.49  ? 225 TYR D N   1 
ATOM   12435 C CA  . TYR D 1 225 ? 22.802  62.844  -10.031 1.00 25.44  ? 225 TYR D CA  1 
ATOM   12436 C C   . TYR D 1 225 ? 22.860  64.054  -10.942 1.00 24.78  ? 225 TYR D C   1 
ATOM   12437 O O   . TYR D 1 225 ? 23.163  65.149  -10.505 1.00 25.06  ? 225 TYR D O   1 
ATOM   12438 C CB  . TYR D 1 225 ? 24.050  61.995  -10.268 1.00 26.69  ? 225 TYR D CB  1 
ATOM   12439 C CG  . TYR D 1 225 ? 24.250  60.828  -9.308  1.00 27.71  ? 225 TYR D CG  1 
ATOM   12440 C CD1 . TYR D 1 225 ? 23.478  60.673  -8.165  1.00 28.52  ? 225 TYR D CD1 1 
ATOM   12441 C CD2 . TYR D 1 225 ? 25.269  59.913  -9.516  1.00 29.22  ? 225 TYR D CD2 1 
ATOM   12442 C CE1 . TYR D 1 225 ? 23.687  59.627  -7.281  1.00 28.98  ? 225 TYR D CE1 1 
ATOM   12443 C CE2 . TYR D 1 225 ? 25.506  58.883  -8.624  1.00 31.89  ? 225 TYR D CE2 1 
ATOM   12444 C CZ  . TYR D 1 225 ? 24.705  58.726  -7.506  1.00 28.56  ? 225 TYR D CZ  1 
ATOM   12445 O OH  . TYR D 1 225 ? 24.942  57.711  -6.627  1.00 26.76  ? 225 TYR D OH  1 
ATOM   12446 N N   . GLU D 1 226 ? 22.485  63.854  -12.200 1.00 25.05  ? 226 GLU D N   1 
ATOM   12447 C CA  . GLU D 1 226 ? 22.557  64.924  -13.170 1.00 25.54  ? 226 GLU D CA  1 
ATOM   12448 C C   . GLU D 1 226 ? 21.569  66.028  -12.807 1.00 25.35  ? 226 GLU D C   1 
ATOM   12449 O O   . GLU D 1 226 ? 21.909  67.217  -12.868 1.00 23.95  ? 226 GLU D O   1 
ATOM   12450 C CB  . GLU D 1 226 ? 22.360  64.289  -14.545 1.00 27.62  ? 226 GLU D CB  1 
ATOM   12451 C CG  . GLU D 1 226 ? 23.622  63.575  -15.031 1.00 30.50  ? 226 GLU D CG  1 
ATOM   12452 C CD  . GLU D 1 226 ? 24.657  64.584  -15.512 1.00 32.47  ? 226 GLU D CD  1 
ATOM   12453 O OE1 . GLU D 1 226 ? 25.544  64.982  -14.708 1.00 32.73  ? 226 GLU D OE1 1 
ATOM   12454 O OE2 . GLU D 1 226 ? 24.546  64.984  -16.698 1.00 33.67  ? 226 GLU D OE2 1 
ATOM   12455 N N   . LEU D 1 227 ? 20.345  65.619  -12.430 1.00 25.21  ? 227 LEU D N   1 
ATOM   12456 C CA  . LEU D 1 227 ? 19.310  66.564  -12.046 1.00 25.45  ? 227 LEU D CA  1 
ATOM   12457 C C   . LEU D 1 227 ? 19.781  67.423  -10.875 1.00 26.04  ? 227 LEU D C   1 
ATOM   12458 O O   . LEU D 1 227 ? 19.583  68.630  -10.895 1.00 31.24  ? 227 LEU D O   1 
ATOM   12459 C CB  . LEU D 1 227 ? 18.018  65.845  -11.688 1.00 27.08  ? 227 LEU D CB  1 
ATOM   12460 C CG  . LEU D 1 227 ? 16.896  66.718  -11.107 1.00 29.54  ? 227 LEU D CG  1 
ATOM   12461 C CD1 . LEU D 1 227 ? 16.452  67.805  -12.064 1.00 27.53  ? 227 LEU D CD1 1 
ATOM   12462 C CD2 . LEU D 1 227 ? 15.701  65.833  -10.742 1.00 32.41  ? 227 LEU D CD2 1 
ATOM   12463 N N   . PHE D 1 228 ? 20.378  66.797  -9.859  1.00 24.39  ? 228 PHE D N   1 
ATOM   12464 C CA  . PHE D 1 228 ? 20.776  67.500  -8.646  1.00 27.49  ? 228 PHE D CA  1 
ATOM   12465 C C   . PHE D 1 228 ? 21.885  68.496  -8.969  1.00 26.81  ? 228 PHE D C   1 
ATOM   12466 O O   . PHE D 1 228 ? 21.908  69.588  -8.403  1.00 26.63  ? 228 PHE D O   1 
ATOM   12467 C CB  . PHE D 1 228 ? 21.236  66.573  -7.506  1.00 28.38  ? 228 PHE D CB  1 
ATOM   12468 C CG  . PHE D 1 228 ? 20.091  65.968  -6.701  1.00 30.12  ? 228 PHE D CG  1 
ATOM   12469 C CD1 . PHE D 1 228 ? 18.942  65.482  -7.323  1.00 29.45  ? 228 PHE D CD1 1 
ATOM   12470 C CD2 . PHE D 1 228 ? 20.138  65.932  -5.308  1.00 31.39  ? 228 PHE D CD2 1 
ATOM   12471 C CE1 . PHE D 1 228 ? 17.899  64.938  -6.580  1.00 30.18  ? 228 PHE D CE1 1 
ATOM   12472 C CE2 . PHE D 1 228 ? 19.079  65.406  -4.574  1.00 28.18  ? 228 PHE D CE2 1 
ATOM   12473 C CZ  . PHE D 1 228 ? 17.973  64.902  -5.211  1.00 29.64  ? 228 PHE D CZ  1 
ATOM   12474 N N   . ARG D 1 229 ? 22.768  68.109  -9.901  1.00 25.17  ? 229 ARG D N   1 
ATOM   12475 C CA  . ARG D 1 229 ? 23.894  68.936  -10.270 1.00 24.91  ? 229 ARG D CA  1 
ATOM   12476 C C   . ARG D 1 229 ? 23.334  70.195  -10.909 1.00 27.48  ? 229 ARG D C   1 
ATOM   12477 O O   . ARG D 1 229 ? 23.645  71.322  -10.493 1.00 29.11  ? 229 ARG D O   1 
ATOM   12478 C CB  . ARG D 1 229 ? 24.842  68.116  -11.149 1.00 23.37  ? 229 ARG D CB  1 
ATOM   12479 C CG  . ARG D 1 229 ? 25.576  67.003  -10.412 1.00 22.43  ? 229 ARG D CG  1 
ATOM   12480 C CD  . ARG D 1 229 ? 26.280  66.105  -11.420 1.00 25.00  ? 229 ARG D CD  1 
ATOM   12481 N NE  . ARG D 1 229 ? 26.962  64.922  -10.879 1.00 25.71  ? 229 ARG D NE  1 
ATOM   12482 C CZ  . ARG D 1 229 ? 27.023  63.687  -11.386 1.00 25.73  ? 229 ARG D CZ  1 
ATOM   12483 N NH1 . ARG D 1 229 ? 26.451  63.354  -12.530 1.00 26.45  ? 229 ARG D NH1 1 
ATOM   12484 N NH2 . ARG D 1 229 ? 27.688  62.762  -10.725 1.00 26.34  ? 229 ARG D NH2 1 
ATOM   12485 N N   . LEU D 1 230 ? 22.426  69.975  -11.859 1.00 27.71  ? 230 LEU D N   1 
ATOM   12486 C CA  . LEU D 1 230 ? 21.788  71.094  -12.521 1.00 28.56  ? 230 LEU D CA  1 
ATOM   12487 C C   . LEU D 1 230 ? 21.011  71.948  -11.516 1.00 26.81  ? 230 LEU D C   1 
ATOM   12488 O O   . LEU D 1 230 ? 21.099  73.180  -11.533 1.00 25.24  ? 230 LEU D O   1 
ATOM   12489 C CB  . LEU D 1 230 ? 20.874  70.640  -13.652 1.00 27.12  ? 230 LEU D CB  1 
ATOM   12490 C CG  . LEU D 1 230 ? 20.091  71.777  -14.315 1.00 25.24  ? 230 LEU D CG  1 
ATOM   12491 C CD1 . LEU D 1 230 ? 21.056  72.823  -14.896 1.00 24.51  ? 230 LEU D CD1 1 
ATOM   12492 C CD2 . LEU D 1 230 ? 19.123  71.224  -15.338 1.00 24.50  ? 230 LEU D CD2 1 
ATOM   12493 N N   . TYR D 1 231 ? 20.193  71.281  -10.708 1.00 25.96  ? 231 TYR D N   1 
ATOM   12494 C CA  . TYR D 1 231 ? 19.357  71.940  -9.714  1.00 28.02  ? 231 TYR D CA  1 
ATOM   12495 C C   . TYR D 1 231 ? 20.199  72.899  -8.858  1.00 29.13  ? 231 TYR D C   1 
ATOM   12496 O O   . TYR D 1 231 ? 19.792  74.046  -8.634  1.00 27.53  ? 231 TYR D O   1 
ATOM   12497 C CB  . TYR D 1 231 ? 18.636  70.880  -8.861  1.00 28.44  ? 231 TYR D CB  1 
ATOM   12498 C CG  . TYR D 1 231 ? 17.761  71.546  -7.820  1.00 25.68  ? 231 TYR D CG  1 
ATOM   12499 C CD1 . TYR D 1 231 ? 18.318  72.056  -6.662  1.00 26.35  ? 231 TYR D CD1 1 
ATOM   12500 C CD2 . TYR D 1 231 ? 16.429  71.794  -8.063  1.00 25.52  ? 231 TYR D CD2 1 
ATOM   12501 C CE1 . TYR D 1 231 ? 17.554  72.713  -5.722  1.00 27.52  ? 231 TYR D CE1 1 
ATOM   12502 C CE2 . TYR D 1 231 ? 15.659  72.511  -7.165  1.00 25.96  ? 231 TYR D CE2 1 
ATOM   12503 C CZ  . TYR D 1 231 ? 16.213  72.936  -5.971  1.00 27.79  ? 231 TYR D CZ  1 
ATOM   12504 O OH  . TYR D 1 231 ? 15.461  73.601  -5.043  1.00 26.83  ? 231 TYR D OH  1 
ATOM   12505 N N   . MET D 1 232 ? 21.367  72.418  -8.383  1.00 29.32  ? 232 MET D N   1 
ATOM   12506 C CA  . MET D 1 232 ? 22.217  73.168  -7.458  1.00 29.21  ? 232 MET D CA  1 
ATOM   12507 C C   . MET D 1 232 ? 22.928  74.320  -8.161  1.00 28.67  ? 232 MET D C   1 
ATOM   12508 O O   . MET D 1 232 ? 23.091  75.399  -7.587  1.00 27.35  ? 232 MET D O   1 
ATOM   12509 C CB  . MET D 1 232 ? 23.281  72.263  -6.828  1.00 30.18  ? 232 MET D CB  1 
ATOM   12510 C CG  . MET D 1 232 ? 22.714  71.186  -5.895  1.00 29.87  ? 232 MET D CG  1 
ATOM   12511 S SD  . MET D 1 232 ? 21.961  71.870  -4.410  1.00 30.98  ? 232 MET D SD  1 
ATOM   12512 C CE  . MET D 1 232 ? 21.098  70.379  -3.901  1.00 33.70  ? 232 MET D CE  1 
ATOM   12513 N N   . PHE D 1 233 ? 23.362  74.067  -9.401  1.00 27.19  ? 233 PHE D N   1 
ATOM   12514 C CA  . PHE D 1 233 ? 23.813  75.119  -10.288 1.00 24.81  ? 233 PHE D CA  1 
ATOM   12515 C C   . PHE D 1 233 ? 22.779  76.240  -10.359 1.00 25.04  ? 233 PHE D C   1 
ATOM   12516 O O   . PHE D 1 233 ? 23.119  77.408  -10.170 1.00 25.89  ? 233 PHE D O   1 
ATOM   12517 C CB  . PHE D 1 233 ? 24.093  74.487  -11.653 1.00 28.26  ? 233 PHE D CB  1 
ATOM   12518 C CG  . PHE D 1 233 ? 24.437  75.503  -12.738 1.00 31.21  ? 233 PHE D CG  1 
ATOM   12519 C CD1 . PHE D 1 233 ? 25.714  76.046  -12.822 1.00 29.83  ? 233 PHE D CD1 1 
ATOM   12520 C CD2 . PHE D 1 233 ? 23.480  75.901  -13.671 1.00 31.68  ? 233 PHE D CD2 1 
ATOM   12521 C CE1 . PHE D 1 233 ? 26.017  76.993  -13.778 1.00 30.90  ? 233 PHE D CE1 1 
ATOM   12522 C CE2 . PHE D 1 233 ? 23.791  76.833  -14.636 1.00 33.13  ? 233 PHE D CE2 1 
ATOM   12523 C CZ  . PHE D 1 233 ? 25.061  77.382  -14.683 1.00 35.24  ? 233 PHE D CZ  1 
ATOM   12524 N N   . LEU D 1 234 ? 21.508  75.900  -10.618 1.00 25.81  ? 234 LEU D N   1 
ATOM   12525 C CA  . LEU D 1 234 ? 20.541  76.902  -11.054 1.00 26.84  ? 234 LEU D CA  1 
ATOM   12526 C C   . LEU D 1 234 ? 20.057  77.802  -9.910  1.00 26.88  ? 234 LEU D C   1 
ATOM   12527 O O   . LEU D 1 234 ? 19.776  78.977  -10.140 1.00 24.55  ? 234 LEU D O   1 
ATOM   12528 C CB  . LEU D 1 234 ? 19.353  76.227  -11.742 1.00 27.09  ? 234 LEU D CB  1 
ATOM   12529 C CG  . LEU D 1 234 ? 19.603  75.578  -13.108 1.00 27.35  ? 234 LEU D CG  1 
ATOM   12530 C CD1 . LEU D 1 234 ? 18.323  74.830  -13.454 1.00 29.55  ? 234 LEU D CD1 1 
ATOM   12531 C CD2 . LEU D 1 234 ? 19.992  76.557  -14.196 1.00 24.35  ? 234 LEU D CD2 1 
ATOM   12532 N N   . HIS D 1 235 ? 19.905  77.246  -8.697  1.00 28.29  ? 235 HIS D N   1 
ATOM   12533 C CA  . HIS D 1 235 ? 19.345  77.976  -7.563  1.00 28.58  ? 235 HIS D CA  1 
ATOM   12534 C C   . HIS D 1 235 ? 20.439  78.638  -6.706  1.00 32.75  ? 235 HIS D C   1 
ATOM   12535 O O   . HIS D 1 235 ? 20.162  79.277  -5.678  1.00 35.74  ? 235 HIS D O   1 
ATOM   12536 C CB  . HIS D 1 235 ? 18.496  77.017  -6.733  1.00 27.71  ? 235 HIS D CB  1 
ATOM   12537 C CG  . HIS D 1 235 ? 17.357  76.370  -7.463  1.00 28.65  ? 235 HIS D CG  1 
ATOM   12538 N ND1 . HIS D 1 235 ? 17.502  75.305  -8.329  1.00 26.06  ? 235 HIS D ND1 1 
ATOM   12539 C CD2 . HIS D 1 235 ? 16.034  76.641  -7.413  1.00 26.13  ? 235 HIS D CD2 1 
ATOM   12540 C CE1 . HIS D 1 235 ? 16.299  74.946  -8.753  1.00 26.87  ? 235 HIS D CE1 1 
ATOM   12541 N NE2 . HIS D 1 235 ? 15.400  75.727  -8.196  1.00 26.90  ? 235 HIS D NE2 1 
ATOM   12542 N N   . SER D 1 236 ? 21.691  78.482  -7.146  1.00 29.66  ? 236 SER D N   1 
ATOM   12543 C CA  . SER D 1 236 ? 22.880  78.946  -6.448  1.00 27.72  ? 236 SER D CA  1 
ATOM   12544 C C   . SER D 1 236 ? 22.767  80.406  -6.024  1.00 26.10  ? 236 SER D C   1 
ATOM   12545 O O   . SER D 1 236 ? 23.092  80.766  -4.893  1.00 23.89  ? 236 SER D O   1 
ATOM   12546 C CB  . SER D 1 236 ? 24.089  78.756  -7.327  1.00 26.36  ? 236 SER D CB  1 
ATOM   12547 O OG  . SER D 1 236 ? 23.897  79.411  -8.578  1.00 24.74  ? 236 SER D OG  1 
ATOM   12548 N N   . ASP D 1 237 ? 22.352  81.262  -6.946  1.00 25.21  ? 237 ASP D N   1 
ATOM   12549 C CA  . ASP D 1 237 ? 22.484  82.687  -6.692  1.00 27.42  ? 237 ASP D CA  1 
ATOM   12550 C C   . ASP D 1 237 ? 21.588  83.452  -7.661  1.00 27.13  ? 237 ASP D C   1 
ATOM   12551 O O   . ASP D 1 237 ? 21.347  82.971  -8.768  1.00 29.34  ? 237 ASP D O   1 
ATOM   12552 C CB  . ASP D 1 237 ? 23.952  83.089  -6.793  1.00 28.09  ? 237 ASP D CB  1 
ATOM   12553 C CG  . ASP D 1 237 ? 24.344  84.371  -6.081  1.00 27.48  ? 237 ASP D CG  1 
ATOM   12554 O OD1 . ASP D 1 237 ? 24.032  84.473  -4.880  1.00 30.75  ? 237 ASP D OD1 1 
ATOM   12555 O OD2 . ASP D 1 237 ? 24.959  85.246  -6.729  1.00 27.60  ? 237 ASP D OD2 1 
ATOM   12556 N N   . HIS D 1 238 ? 21.140  84.642  -7.242  1.00 26.44  ? 238 HIS D N   1 
ATOM   12557 C CA  . HIS D 1 238 ? 20.209  85.469  -7.996  1.00 27.07  ? 238 HIS D CA  1 
ATOM   12558 C C   . HIS D 1 238 ? 20.219  86.880  -7.398  1.00 25.75  ? 238 HIS D C   1 
ATOM   12559 O O   . HIS D 1 238 ? 19.215  87.350  -6.844  1.00 25.35  ? 238 HIS D O   1 
ATOM   12560 C CB  . HIS D 1 238 ? 18.820  84.812  -8.014  1.00 30.29  ? 238 HIS D CB  1 
ATOM   12561 C CG  . HIS D 1 238 ? 18.036  85.004  -9.280  1.00 33.88  ? 238 HIS D CG  1 
ATOM   12562 N ND1 . HIS D 1 238 ? 16.890  85.771  -9.375  1.00 32.42  ? 238 HIS D ND1 1 
ATOM   12563 C CD2 . HIS D 1 238 ? 18.221  84.451  -10.515 1.00 36.36  ? 238 HIS D CD2 1 
ATOM   12564 C CE1 . HIS D 1 238 ? 16.420  85.688  -10.629 1.00 37.98  ? 238 HIS D CE1 1 
ATOM   12565 N NE2 . HIS D 1 238 ? 17.211  84.892  -11.347 1.00 33.74  ? 238 HIS D NE2 1 
ATOM   12566 N N   . GLU D 1 239 ? 21.388  87.530  -7.507  1.00 26.18  ? 239 GLU D N   1 
ATOM   12567 C CA  . GLU D 1 239 ? 21.639  88.871  -6.987  1.00 29.22  ? 239 GLU D CA  1 
ATOM   12568 C C   . GLU D 1 239 ? 21.728  88.884  -5.456  1.00 30.38  ? 239 GLU D C   1 
ATOM   12569 O O   . GLU D 1 239 ? 21.670  87.837  -4.804  1.00 29.69  ? 239 GLU D O   1 
ATOM   12570 C CB  . GLU D 1 239 ? 20.579  89.866  -7.449  1.00 30.69  ? 239 GLU D CB  1 
ATOM   12571 C CG  . GLU D 1 239 ? 21.019  90.708  -8.634  1.00 32.49  ? 239 GLU D CG  1 
ATOM   12572 C CD  . GLU D 1 239 ? 20.027  91.797  -8.962  1.00 33.10  ? 239 GLU D CD  1 
ATOM   12573 O OE1 . GLU D 1 239 ? 20.271  92.374  -10.026 1.00 35.94  ? 239 GLU D OE1 1 
ATOM   12574 O OE2 . GLU D 1 239 ? 19.062  92.066  -8.204  1.00 39.26  ? 239 GLU D OE2 1 
ATOM   12575 N N   . GLY D 1 240 ? 21.888  90.098  -4.908  1.00 29.09  ? 240 GLY D N   1 
ATOM   12576 C CA  . GLY D 1 240 ? 22.015  90.320  -3.478  1.00 32.43  ? 240 GLY D CA  1 
ATOM   12577 C C   . GLY D 1 240 ? 20.690  90.608  -2.766  1.00 33.27  ? 240 GLY D C   1 
ATOM   12578 O O   . GLY D 1 240 ? 20.638  90.510  -1.534  1.00 35.94  ? 240 GLY D O   1 
ATOM   12579 N N   . GLY D 1 241 ? 19.636  90.915  -3.542  1.00 31.68  ? 241 GLY D N   1 
ATOM   12580 C CA  . GLY D 1 241 ? 18.439  91.585  -3.050  1.00 28.91  ? 241 GLY D CA  1 
ATOM   12581 C C   . GLY D 1 241 ? 17.290  90.648  -2.654  1.00 27.77  ? 241 GLY D C   1 
ATOM   12582 O O   . GLY D 1 241 ? 16.364  91.074  -1.962  1.00 27.79  ? 241 GLY D O   1 
ATOM   12583 N N   . ASN D 1 242 ? 17.313  89.377  -3.080  1.00 28.63  ? 242 ASN D N   1 
ATOM   12584 C CA  . ASN D 1 242 ? 16.302  88.432  -2.622  1.00 27.66  ? 242 ASN D CA  1 
ATOM   12585 C C   . ASN D 1 242 ? 16.447  88.276  -1.103  1.00 28.03  ? 242 ASN D C   1 
ATOM   12586 O O   . ASN D 1 242 ? 17.487  88.605  -0.513  1.00 27.80  ? 242 ASN D O   1 
ATOM   12587 C CB  . ASN D 1 242 ? 16.329  87.121  -3.406  1.00 26.26  ? 242 ASN D CB  1 
ATOM   12588 C CG  . ASN D 1 242 ? 17.555  86.271  -3.144  1.00 26.30  ? 242 ASN D CG  1 
ATOM   12589 O OD1 . ASN D 1 242 ? 17.676  85.680  -2.064  1.00 28.28  ? 242 ASN D OD1 1 
ATOM   12590 N ND2 . ASN D 1 242 ? 18.449  86.140  -4.121  1.00 26.55  ? 242 ASN D ND2 1 
ATOM   12591 N N   . VAL D 1 243 ? 15.376  87.773  -0.486  1.00 26.42  ? 243 VAL D N   1 
ATOM   12592 C CA  . VAL D 1 243 ? 15.239  87.722  0.956   1.00 27.14  ? 243 VAL D CA  1 
ATOM   12593 C C   . VAL D 1 243 ? 16.357  86.888  1.585   1.00 26.65  ? 243 VAL D C   1 
ATOM   12594 O O   . VAL D 1 243 ? 16.941  87.332  2.564   1.00 24.96  ? 243 VAL D O   1 
ATOM   12595 C CB  . VAL D 1 243 ? 13.840  87.183  1.295   1.00 29.98  ? 243 VAL D CB  1 
ATOM   12596 C CG1 . VAL D 1 243 ? 13.740  86.738  2.749   1.00 32.46  ? 243 VAL D CG1 1 
ATOM   12597 C CG2 . VAL D 1 243 ? 12.756  88.211  0.973   1.00 29.03  ? 243 VAL D CG2 1 
ATOM   12598 N N   . SER D 1 244 ? 16.679  85.711  1.017   1.00 26.67  ? 244 SER D N   1 
ATOM   12599 C CA  . SER D 1 244 ? 17.676  84.830  1.616   1.00 25.54  ? 244 SER D CA  1 
ATOM   12600 C C   . SER D 1 244 ? 19.074  85.455  1.519   1.00 27.24  ? 244 SER D C   1 
ATOM   12601 O O   . SER D 1 244 ? 19.734  85.615  2.545   1.00 26.81  ? 244 SER D O   1 
ATOM   12602 C CB  . SER D 1 244 ? 17.621  83.420  1.076   1.00 24.21  ? 244 SER D CB  1 
ATOM   12603 O OG  . SER D 1 244 ? 17.695  83.347  -0.338  1.00 24.47  ? 244 SER D OG  1 
ATOM   12604 N N   . ALA D 1 245 ? 19.456  85.919  0.316   1.00 24.40  ? 245 ALA D N   1 
ATOM   12605 C CA  . ALA D 1 245 ? 20.739  86.555  0.079   1.00 21.96  ? 245 ALA D CA  1 
ATOM   12606 C C   . ALA D 1 245 ? 20.849  87.829  0.895   1.00 21.31  ? 245 ALA D C   1 
ATOM   12607 O O   . ALA D 1 245 ? 21.906  88.145  1.397   1.00 22.35  ? 245 ALA D O   1 
ATOM   12608 C CB  . ALA D 1 245 ? 20.955  86.858  -1.407  1.00 20.89  ? 245 ALA D CB  1 
ATOM   12609 N N   . HIS D 1 246 ? 19.779  88.602  0.974   1.00 24.30  ? 246 HIS D N   1 
ATOM   12610 C CA  . HIS D 1 246 ? 19.848  89.857  1.702   1.00 24.59  ? 246 HIS D CA  1 
ATOM   12611 C C   . HIS D 1 246 ? 19.945  89.562  3.210   1.00 25.90  ? 246 HIS D C   1 
ATOM   12612 O O   . HIS D 1 246 ? 20.731  90.193  3.939   1.00 23.33  ? 246 HIS D O   1 
ATOM   12613 C CB  . HIS D 1 246 ? 18.699  90.763  1.250   1.00 23.90  ? 246 HIS D CB  1 
ATOM   12614 C CG  . HIS D 1 246 ? 18.660  92.095  1.930   1.00 23.66  ? 246 HIS D CG  1 
ATOM   12615 N ND1 . HIS D 1 246 ? 17.511  92.851  2.025   1.00 22.98  ? 246 HIS D ND1 1 
ATOM   12616 C CD2 . HIS D 1 246 ? 19.609  92.792  2.553   1.00 24.43  ? 246 HIS D CD2 1 
ATOM   12617 C CE1 . HIS D 1 246 ? 17.769  93.964  2.690   1.00 23.41  ? 246 HIS D CE1 1 
ATOM   12618 N NE2 . HIS D 1 246 ? 19.044  93.959  2.999   1.00 26.35  ? 246 HIS D NE2 1 
ATOM   12619 N N   . THR D 1 247 ? 19.192  88.562  3.696   1.00 25.02  ? 247 THR D N   1 
ATOM   12620 C CA  . THR D 1 247 ? 19.254  88.244  5.120   1.00 24.70  ? 247 THR D CA  1 
ATOM   12621 C C   . THR D 1 247 ? 20.704  87.892  5.475   1.00 22.78  ? 247 THR D C   1 
ATOM   12622 O O   . THR D 1 247 ? 21.254  88.359  6.468   1.00 20.93  ? 247 THR D O   1 
ATOM   12623 C CB  . THR D 1 247 ? 18.282  87.118  5.459   1.00 25.21  ? 247 THR D CB  1 
ATOM   12624 O OG1 . THR D 1 247 ? 17.009  87.710  5.249   1.00 24.39  ? 247 THR D OG1 1 
ATOM   12625 C CG2 . THR D 1 247 ? 18.391  86.636  6.899   1.00 25.84  ? 247 THR D CG2 1 
ATOM   12626 N N   . ASN D 1 248 ? 21.332  87.109  4.609   1.00 22.30  ? 248 ASN D N   1 
ATOM   12627 C CA  . ASN D 1 248 ? 22.706  86.689  4.809   1.00 24.78  ? 248 ASN D CA  1 
ATOM   12628 C C   . ASN D 1 248 ? 23.633  87.911  4.893   1.00 28.00  ? 248 ASN D C   1 
ATOM   12629 O O   . ASN D 1 248 ? 24.517  87.954  5.745   1.00 26.02  ? 248 ASN D O   1 
ATOM   12630 C CB  . ASN D 1 248 ? 23.120  85.712  3.718   1.00 23.52  ? 248 ASN D CB  1 
ATOM   12631 C CG  . ASN D 1 248 ? 24.519  85.220  3.928   1.00 24.32  ? 248 ASN D CG  1 
ATOM   12632 O OD1 . ASN D 1 248 ? 25.393  85.446  3.086   1.00 23.41  ? 248 ASN D OD1 1 
ATOM   12633 N ND2 . ASN D 1 248 ? 24.733  84.519  5.029   1.00 26.78  ? 248 ASN D ND2 1 
ATOM   12634 N N   . LEU D 1 249 ? 23.434  88.911  4.015   1.00 27.48  ? 249 LEU D N   1 
ATOM   12635 C CA  . LEU D 1 249 ? 24.320  90.060  3.981   1.00 27.26  ? 249 LEU D CA  1 
ATOM   12636 C C   . LEU D 1 249 ? 24.161  90.882  5.254   1.00 26.24  ? 249 LEU D C   1 
ATOM   12637 O O   . LEU D 1 249 ? 25.147  91.366  5.823   1.00 23.37  ? 249 LEU D O   1 
ATOM   12638 C CB  . LEU D 1 249 ? 24.039  90.903  2.740   1.00 29.19  ? 249 LEU D CB  1 
ATOM   12639 C CG  . LEU D 1 249 ? 24.596  90.372  1.413   1.00 29.46  ? 249 LEU D CG  1 
ATOM   12640 C CD1 . LEU D 1 249 ? 24.181  91.284  0.272   1.00 30.68  ? 249 LEU D CD1 1 
ATOM   12641 C CD2 . LEU D 1 249 ? 26.089  90.235  1.428   1.00 29.38  ? 249 LEU D CD2 1 
ATOM   12642 N N   . LEU D 1 250 ? 22.889  91.052  5.637   1.00 27.98  ? 250 LEU D N   1 
ATOM   12643 C CA  . LEU D 1 250 ? 22.466  91.864  6.768   1.00 27.24  ? 250 LEU D CA  1 
ATOM   12644 C C   . LEU D 1 250 ? 23.084  91.344  8.065   1.00 26.83  ? 250 LEU D C   1 
ATOM   12645 O O   . LEU D 1 250 ? 23.723  92.098  8.790   1.00 27.37  ? 250 LEU D O   1 
ATOM   12646 C CB  . LEU D 1 250 ? 20.938  91.876  6.860   1.00 25.51  ? 250 LEU D CB  1 
ATOM   12647 C CG  . LEU D 1 250 ? 20.316  92.727  7.978   1.00 24.00  ? 250 LEU D CG  1 
ATOM   12648 C CD1 . LEU D 1 250 ? 20.851  94.138  8.016   1.00 24.14  ? 250 LEU D CD1 1 
ATOM   12649 C CD2 . LEU D 1 250 ? 18.799  92.806  7.842   1.00 23.65  ? 250 LEU D CD2 1 
ATOM   12650 N N   . VAL D 1 251 ? 22.866  90.067  8.371   1.00 23.86  ? 251 VAL D N   1 
ATOM   12651 C CA  . VAL D 1 251 ? 23.379  89.515  9.613   1.00 24.61  ? 251 VAL D CA  1 
ATOM   12652 C C   . VAL D 1 251 ? 24.918  89.456  9.561   1.00 27.00  ? 251 VAL D C   1 
ATOM   12653 O O   . VAL D 1 251 ? 25.594  89.697  10.573  1.00 25.69  ? 251 VAL D O   1 
ATOM   12654 C CB  . VAL D 1 251 ? 22.714  88.141  9.847   1.00 25.05  ? 251 VAL D CB  1 
ATOM   12655 C CG1 . VAL D 1 251 ? 23.429  87.323  10.917  1.00 24.24  ? 251 VAL D CG1 1 
ATOM   12656 C CG2 . VAL D 1 251 ? 21.204  88.272  10.136  1.00 25.35  ? 251 VAL D CG2 1 
ATOM   12657 N N   . ASN D 1 252 ? 25.470  89.179  8.365   1.00 24.87  ? 252 ASN D N   1 
ATOM   12658 C CA  . ASN D 1 252 ? 26.907  89.174  8.135   1.00 23.42  ? 252 ASN D CA  1 
ATOM   12659 C C   . ASN D 1 252 ? 27.465  90.558  8.408   1.00 23.94  ? 252 ASN D C   1 
ATOM   12660 O O   . ASN D 1 252 ? 28.577  90.649  8.895   1.00 28.86  ? 252 ASN D O   1 
ATOM   12661 C CB  . ASN D 1 252 ? 27.305  88.734  6.725   1.00 24.63  ? 252 ASN D CB  1 
ATOM   12662 C CG  . ASN D 1 252 ? 28.773  88.933  6.404   1.00 26.28  ? 252 ASN D CG  1 
ATOM   12663 O OD1 . ASN D 1 252 ? 29.189  90.017  5.984   1.00 24.71  ? 252 ASN D OD1 1 
ATOM   12664 N ND2 . ASN D 1 252 ? 29.577  87.892  6.561   1.00 26.92  ? 252 ASN D ND2 1 
ATOM   12665 N N   . SER D 1 253 ? 26.724  91.626  8.113   1.00 24.78  ? 253 SER D N   1 
ATOM   12666 C CA  . SER D 1 253 ? 27.323  92.953  8.188   1.00 25.63  ? 253 SER D CA  1 
ATOM   12667 C C   . SER D 1 253 ? 27.621  93.375  9.635   1.00 29.95  ? 253 SER D C   1 
ATOM   12668 O O   . SER D 1 253 ? 28.373  94.326  9.842   1.00 30.86  ? 253 SER D O   1 
ATOM   12669 C CB  . SER D 1 253 ? 26.460  93.959  7.510   1.00 24.74  ? 253 SER D CB  1 
ATOM   12670 O OG  . SER D 1 253 ? 25.304  94.237  8.289   1.00 24.54  ? 253 SER D OG  1 
ATOM   12671 N N   . ALA D 1 254 ? 27.051  92.682  10.642  1.00 30.03  ? 254 ALA D N   1 
ATOM   12672 C CA  . ALA D 1 254 ? 27.357  92.990  12.040  1.00 30.71  ? 254 ALA D CA  1 
ATOM   12673 C C   . ALA D 1 254 ? 28.483  92.107  12.594  1.00 29.47  ? 254 ALA D C   1 
ATOM   12674 O O   . ALA D 1 254 ? 28.707  92.130  13.794  1.00 27.85  ? 254 ALA D O   1 
ATOM   12675 C CB  . ALA D 1 254 ? 26.106  92.862  12.889  1.00 29.74  ? 254 ALA D CB  1 
ATOM   12676 N N   . TYR D 1 255 ? 29.156  91.336  11.718  1.00 27.27  ? 255 TYR D N   1 
ATOM   12677 C CA  . TYR D 1 255 ? 30.266  90.444  12.025  1.00 26.76  ? 255 TYR D CA  1 
ATOM   12678 C C   . TYR D 1 255 ? 29.791  89.137  12.666  1.00 26.86  ? 255 TYR D C   1 
ATOM   12679 O O   . TYR D 1 255 ? 30.561  88.471  13.355  1.00 29.25  ? 255 TYR D O   1 
ATOM   12680 C CB  . TYR D 1 255 ? 31.370  91.093  12.864  1.00 29.18  ? 255 TYR D CB  1 
ATOM   12681 C CG  . TYR D 1 255 ? 32.181  92.222  12.231  1.00 30.47  ? 255 TYR D CG  1 
ATOM   12682 C CD1 . TYR D 1 255 ? 32.070  92.572  10.888  1.00 31.27  ? 255 TYR D CD1 1 
ATOM   12683 C CD2 . TYR D 1 255 ? 33.087  92.926  13.005  1.00 29.95  ? 255 TYR D CD2 1 
ATOM   12684 C CE1 . TYR D 1 255 ? 32.811  93.611  10.353  1.00 31.01  ? 255 TYR D CE1 1 
ATOM   12685 C CE2 . TYR D 1 255 ? 33.837  93.956  12.484  1.00 31.96  ? 255 TYR D CE2 1 
ATOM   12686 C CZ  . TYR D 1 255 ? 33.705  94.293  11.156  1.00 31.55  ? 255 TYR D CZ  1 
ATOM   12687 O OH  . TYR D 1 255 ? 34.495  95.292  10.700  1.00 33.24  ? 255 TYR D OH  1 
ATOM   12688 N N   . SER D 1 256 ? 28.538  88.757  12.410  1.00 25.35  ? 256 SER D N   1 
ATOM   12689 C CA  . SER D 1 256 ? 28.054  87.434  12.735  1.00 23.75  ? 256 SER D CA  1 
ATOM   12690 C C   . SER D 1 256 ? 28.525  86.452  11.668  1.00 23.63  ? 256 SER D C   1 
ATOM   12691 O O   . SER D 1 256 ? 28.413  86.715  10.467  1.00 23.61  ? 256 SER D O   1 
ATOM   12692 C CB  . SER D 1 256 ? 26.558  87.388  12.870  1.00 25.25  ? 256 SER D CB  1 
ATOM   12693 O OG  . SER D 1 256 ? 26.050  88.273  13.863  1.00 29.33  ? 256 SER D OG  1 
ATOM   12694 N N   . ASP D 1 257 ? 28.976  85.280  12.137  1.00 22.24  ? 257 ASP D N   1 
ATOM   12695 C CA  . ASP D 1 257 ? 29.609  84.267  11.317  1.00 21.28  ? 257 ASP D CA  1 
ATOM   12696 C C   . ASP D 1 257 ? 28.586  83.584  10.416  1.00 20.55  ? 257 ASP D C   1 
ATOM   12697 O O   . ASP D 1 257 ? 27.393  83.821  10.554  1.00 20.27  ? 257 ASP D O   1 
ATOM   12698 C CB  . ASP D 1 257 ? 30.283  83.245  12.212  1.00 20.36  ? 257 ASP D CB  1 
ATOM   12699 C CG  . ASP D 1 257 ? 29.330  82.411  13.053  1.00 20.02  ? 257 ASP D CG  1 
ATOM   12700 O OD1 . ASP D 1 257 ? 28.567  81.597  12.466  1.00 18.72  ? 257 ASP D OD1 1 
ATOM   12701 O OD2 . ASP D 1 257 ? 29.375  82.586  14.289  1.00 19.96  ? 257 ASP D OD2 1 
ATOM   12702 N N   . ILE D 1 258 ? 29.061  82.681  9.538   1.00 20.69  ? 258 ILE D N   1 
ATOM   12703 C CA  . ILE D 1 258 ? 28.254  82.177  8.441   1.00 21.43  ? 258 ILE D CA  1 
ATOM   12704 C C   . ILE D 1 258 ? 27.137  81.277  8.973   1.00 24.64  ? 258 ILE D C   1 
ATOM   12705 O O   . ILE D 1 258 ? 26.060  81.224  8.375   1.00 24.70  ? 258 ILE D O   1 
ATOM   12706 C CB  . ILE D 1 258 ? 29.109  81.464  7.384   1.00 22.82  ? 258 ILE D CB  1 
ATOM   12707 C CG1 . ILE D 1 258 ? 28.317  81.180  6.091   1.00 24.69  ? 258 ILE D CG1 1 
ATOM   12708 C CG2 . ILE D 1 258 ? 29.739  80.181  7.923   1.00 23.00  ? 258 ILE D CG2 1 
ATOM   12709 C CD1 . ILE D 1 258 ? 27.926  82.413  5.294   1.00 23.60  ? 258 ILE D CD1 1 
ATOM   12710 N N   . TYR D 1 259 ? 27.356  80.606  10.121  1.00 23.88  ? 259 TYR D N   1 
ATOM   12711 C CA  . TYR D 1 259 ? 26.332  79.727  10.654  1.00 22.23  ? 259 TYR D CA  1 
ATOM   12712 C C   . TYR D 1 259 ? 25.133  80.591  11.080  1.00 22.71  ? 259 TYR D C   1 
ATOM   12713 O O   . TYR D 1 259 ? 23.971  80.265  10.824  1.00 21.82  ? 259 TYR D O   1 
ATOM   12714 C CB  . TYR D 1 259 ? 27.021  78.870  11.715  1.00 22.23  ? 259 TYR D CB  1 
ATOM   12715 C CG  . TYR D 1 259 ? 28.105  77.910  11.233  1.00 23.17  ? 259 TYR D CG  1 
ATOM   12716 C CD1 . TYR D 1 259 ? 27.791  76.627  10.771  1.00 23.31  ? 259 TYR D CD1 1 
ATOM   12717 C CD2 . TYR D 1 259 ? 29.447  78.255  11.305  1.00 23.06  ? 259 TYR D CD2 1 
ATOM   12718 C CE1 . TYR D 1 259 ? 28.774  75.744  10.342  1.00 23.31  ? 259 TYR D CE1 1 
ATOM   12719 C CE2 . TYR D 1 259 ? 30.444  77.378  10.895  1.00 23.05  ? 259 TYR D CE2 1 
ATOM   12720 C CZ  . TYR D 1 259 ? 30.115  76.125  10.400  1.00 25.50  ? 259 TYR D CZ  1 
ATOM   12721 O OH  . TYR D 1 259 ? 31.131  75.278  9.995   1.00 23.60  ? 259 TYR D OH  1 
ATOM   12722 N N   . ARG D 1 260 ? 25.417  81.742  11.683  1.00 21.47  ? 260 ARG D N   1 
ATOM   12723 C CA  . ARG D 1 260 ? 24.370  82.657  12.088  1.00 23.54  ? 260 ARG D CA  1 
ATOM   12724 C C   . ARG D 1 260 ? 23.693  83.279  10.867  1.00 24.56  ? 260 ARG D C   1 
ATOM   12725 O O   . ARG D 1 260 ? 22.467  83.287  10.775  1.00 25.57  ? 260 ARG D O   1 
ATOM   12726 C CB  . ARG D 1 260 ? 24.951  83.719  13.034  1.00 23.79  ? 260 ARG D CB  1 
ATOM   12727 C CG  . ARG D 1 260 ? 24.976  83.200  14.464  1.00 26.19  ? 260 ARG D CG  1 
ATOM   12728 C CD  . ARG D 1 260 ? 25.779  84.054  15.417  1.00 27.57  ? 260 ARG D CD  1 
ATOM   12729 N NE  . ARG D 1 260 ? 25.763  83.590  16.813  1.00 29.71  ? 260 ARG D NE  1 
ATOM   12730 C CZ  . ARG D 1 260 ? 26.557  84.070  17.783  1.00 29.23  ? 260 ARG D CZ  1 
ATOM   12731 N NH1 . ARG D 1 260 ? 27.397  85.053  17.509  1.00 29.20  ? 260 ARG D NH1 1 
ATOM   12732 N NH2 . ARG D 1 260 ? 26.501  83.591  19.013  1.00 27.53  ? 260 ARG D NH2 1 
ATOM   12733 N N   . SER D 1 261 ? 24.488  83.846  9.954   1.00 26.11  ? 261 SER D N   1 
ATOM   12734 C CA  . SER D 1 261 ? 23.912  84.568  8.823   1.00 28.38  ? 261 SER D CA  1 
ATOM   12735 C C   . SER D 1 261 ? 23.161  83.613  7.882   1.00 25.84  ? 261 SER D C   1 
ATOM   12736 O O   . SER D 1 261 ? 22.102  83.974  7.374   1.00 24.42  ? 261 SER D O   1 
ATOM   12737 C CB  . SER D 1 261 ? 24.954  85.420  8.072   1.00 26.29  ? 261 SER D CB  1 
ATOM   12738 O OG  . SER D 1 261 ? 25.864  84.610  7.351   1.00 25.09  ? 261 SER D OG  1 
ATOM   12739 N N   . PHE D 1 262 ? 23.676  82.385  7.682   1.00 24.32  ? 262 PHE D N   1 
ATOM   12740 C CA  . PHE D 1 262 ? 23.040  81.466  6.750   1.00 23.18  ? 262 PHE D CA  1 
ATOM   12741 C C   . PHE D 1 262 ? 21.768  80.867  7.371   1.00 22.53  ? 262 PHE D C   1 
ATOM   12742 O O   . PHE D 1 262 ? 20.739  80.838  6.704   1.00 22.95  ? 262 PHE D O   1 
ATOM   12743 C CB  . PHE D 1 262 ? 24.008  80.438  6.143   1.00 24.10  ? 262 PHE D CB  1 
ATOM   12744 C CG  . PHE D 1 262 ? 23.360  79.633  5.018   1.00 25.01  ? 262 PHE D CG  1 
ATOM   12745 C CD1 . PHE D 1 262 ? 22.893  80.270  3.874   1.00 27.05  ? 262 PHE D CD1 1 
ATOM   12746 C CD2 . PHE D 1 262 ? 23.150  78.270  5.140   1.00 22.16  ? 262 PHE D CD2 1 
ATOM   12747 C CE1 . PHE D 1 262 ? 22.267  79.564  2.879   1.00 25.71  ? 262 PHE D CE1 1 
ATOM   12748 C CE2 . PHE D 1 262 ? 22.521  77.574  4.148   1.00 22.95  ? 262 PHE D CE2 1 
ATOM   12749 C CZ  . PHE D 1 262 ? 22.087  78.221  3.018   1.00 25.67  ? 262 PHE D CZ  1 
ATOM   12750 N N   . SER D 1 263 ? 21.805  80.400  8.621   1.00 21.32  ? 263 SER D N   1 
ATOM   12751 C CA  . SER D 1 263 ? 20.601  79.925  9.292   1.00 23.38  ? 263 SER D CA  1 
ATOM   12752 C C   . SER D 1 263 ? 19.492  80.993  9.289   1.00 23.60  ? 263 SER D C   1 
ATOM   12753 O O   . SER D 1 263 ? 18.331  80.696  9.003   1.00 22.57  ? 263 SER D O   1 
ATOM   12754 C CB  . SER D 1 263 ? 20.885  79.453  10.714  1.00 24.08  ? 263 SER D CB  1 
ATOM   12755 O OG  . SER D 1 263 ? 21.351  80.542  11.505  1.00 24.60  ? 263 SER D OG  1 
ATOM   12756 N N   . ALA D 1 264 ? 19.837  82.245  9.604   1.00 23.74  ? 264 ALA D N   1 
ATOM   12757 C CA  . ALA D 1 264 ? 18.898  83.340  9.410   1.00 26.11  ? 264 ALA D CA  1 
ATOM   12758 C C   . ALA D 1 264 ? 18.281  83.302  8.004   1.00 28.04  ? 264 ALA D C   1 
ATOM   12759 O O   . ALA D 1 264 ? 17.065  83.431  7.840   1.00 24.78  ? 264 ALA D O   1 
ATOM   12760 C CB  . ALA D 1 264 ? 19.611  84.652  9.646   1.00 27.50  ? 264 ALA D CB  1 
ATOM   12761 N N   . ALA D 1 265 ? 19.144  83.180  6.985   1.00 25.66  ? 265 ALA D N   1 
ATOM   12762 C CA  . ALA D 1 265 ? 18.683  83.217  5.611   1.00 26.79  ? 265 ALA D CA  1 
ATOM   12763 C C   . ALA D 1 265 ? 17.676  82.112  5.332   1.00 24.31  ? 265 ALA D C   1 
ATOM   12764 O O   . ALA D 1 265 ? 16.675  82.360  4.677   1.00 23.89  ? 265 ALA D O   1 
ATOM   12765 C CB  . ALA D 1 265 ? 19.842  83.071  4.676   1.00 30.93  ? 265 ALA D CB  1 
ATOM   12766 N N   . MET D 1 266 ? 17.969  80.898  5.797   1.00 22.04  ? 266 MET D N   1 
ATOM   12767 C CA  . MET D 1 266 ? 17.053  79.786  5.632   1.00 23.26  ? 266 MET D CA  1 
ATOM   12768 C C   . MET D 1 266 ? 15.724  80.074  6.339   1.00 23.51  ? 266 MET D C   1 
ATOM   12769 O O   . MET D 1 266 ? 14.683  79.658  5.850   1.00 24.26  ? 266 MET D O   1 
ATOM   12770 C CB  . MET D 1 266 ? 17.645  78.486  6.179   1.00 23.13  ? 266 MET D CB  1 
ATOM   12771 C CG  . MET D 1 266 ? 18.860  78.053  5.431   1.00 23.02  ? 266 MET D CG  1 
ATOM   12772 S SD  . MET D 1 266 ? 18.552  77.954  3.655   1.00 21.78  ? 266 MET D SD  1 
ATOM   12773 C CE  . MET D 1 266 ? 18.964  79.601  3.063   1.00 20.44  ? 266 MET D CE  1 
ATOM   12774 N N   . ASN D 1 267 ? 15.737  80.787  7.472   1.00 24.01  ? 267 ASN D N   1 
ATOM   12775 C CA  . ASN D 1 267 ? 14.492  81.240  8.086   1.00 25.16  ? 267 ASN D CA  1 
ATOM   12776 C C   . ASN D 1 267 ? 13.670  82.100  7.107   1.00 29.81  ? 267 ASN D C   1 
ATOM   12777 O O   . ASN D 1 267 ? 12.438  82.013  7.089   1.00 27.98  ? 267 ASN D O   1 
ATOM   12778 C CB  . ASN D 1 267 ? 14.744  81.957  9.406   1.00 24.90  ? 267 ASN D CB  1 
ATOM   12779 C CG  . ASN D 1 267 ? 14.973  81.025  10.576  1.00 23.92  ? 267 ASN D CG  1 
ATOM   12780 O OD1 . ASN D 1 267 ? 14.990  79.794  10.439  1.00 23.26  ? 267 ASN D OD1 1 
ATOM   12781 N ND2 . ASN D 1 267 ? 15.111  81.617  11.746  1.00 24.01  ? 267 ASN D ND2 1 
ATOM   12782 N N   . GLY D 1 268 ? 14.351  82.909  6.275   1.00 30.59  ? 268 GLY D N   1 
ATOM   12783 C CA  . GLY D 1 268 ? 13.695  83.726  5.259   1.00 32.90  ? 268 GLY D CA  1 
ATOM   12784 C C   . GLY D 1 268 ? 13.206  82.921  4.043   1.00 28.91  ? 268 GLY D C   1 
ATOM   12785 O O   . GLY D 1 268 ? 12.129  83.205  3.509   1.00 25.39  ? 268 GLY D O   1 
ATOM   12786 N N   . LEU D 1 269 ? 14.012  81.937  3.616   1.00 26.36  ? 269 LEU D N   1 
ATOM   12787 C CA  . LEU D 1 269 ? 13.687  81.081  2.493   1.00 27.78  ? 269 LEU D CA  1 
ATOM   12788 C C   . LEU D 1 269 ? 12.511  80.187  2.868   1.00 30.34  ? 269 LEU D C   1 
ATOM   12789 O O   . LEU D 1 269 ? 11.756  79.791  1.978   1.00 35.14  ? 269 LEU D O   1 
ATOM   12790 C CB  . LEU D 1 269 ? 14.890  80.238  2.071   1.00 31.02  ? 269 LEU D CB  1 
ATOM   12791 C CG  . LEU D 1 269 ? 14.787  79.436  0.762   1.00 30.01  ? 269 LEU D CG  1 
ATOM   12792 C CD1 . LEU D 1 269 ? 14.647  80.340  -0.449  1.00 30.41  ? 269 LEU D CD1 1 
ATOM   12793 C CD2 . LEU D 1 269 ? 16.007  78.558  0.564   1.00 28.30  ? 269 LEU D CD2 1 
ATOM   12794 N N   . ALA D 1 270 ? 12.349  79.892  4.169   1.00 26.96  ? 270 ALA D N   1 
ATOM   12795 C CA  . ALA D 1 270 ? 11.223  79.095  4.637   1.00 27.06  ? 270 ALA D CA  1 
ATOM   12796 C C   . ALA D 1 270 ? 9.896   79.825  4.436   1.00 27.86  ? 270 ALA D C   1 
ATOM   12797 O O   . ALA D 1 270 ? 8.849   79.195  4.523   1.00 25.21  ? 270 ALA D O   1 
ATOM   12798 C CB  . ALA D 1 270 ? 11.402  78.752  6.085   1.00 27.62  ? 270 ALA D CB  1 
ATOM   12799 N N   . GLY D 1 271 ? 9.960   81.148  4.188   1.00 30.28  ? 271 GLY D N   1 
ATOM   12800 C CA  . GLY D 1 271 ? 8.792   82.004  4.032   1.00 31.76  ? 271 GLY D CA  1 
ATOM   12801 C C   . GLY D 1 271 ? 8.009   81.739  2.738   1.00 31.54  ? 271 GLY D C   1 
ATOM   12802 O O   . GLY D 1 271 ? 8.609   81.534  1.685   1.00 29.02  ? 271 GLY D O   1 
ATOM   12803 N N   . PRO D 1 272 ? 6.651   81.696  2.789   1.00 34.16  ? 272 PRO D N   1 
ATOM   12804 C CA  . PRO D 1 272 ? 5.821   81.417  1.607   1.00 36.23  ? 272 PRO D CA  1 
ATOM   12805 C C   . PRO D 1 272 ? 5.998   82.300  0.377   1.00 34.42  ? 272 PRO D C   1 
ATOM   12806 O O   . PRO D 1 272 ? 5.772   81.828  -0.723  1.00 33.89  ? 272 PRO D O   1 
ATOM   12807 C CB  . PRO D 1 272 ? 4.377   81.500  2.128   1.00 36.39  ? 272 PRO D CB  1 
ATOM   12808 C CG  . PRO D 1 272 ? 4.482   81.195  3.620   1.00 35.31  ? 272 PRO D CG  1 
ATOM   12809 C CD  . PRO D 1 272 ? 5.845   81.756  4.020   1.00 34.77  ? 272 PRO D CD  1 
ATOM   12810 N N   . LEU D 1 273 ? 6.423   83.555  0.544   1.00 33.40  ? 273 LEU D N   1 
ATOM   12811 C CA  . LEU D 1 273 ? 6.692   84.395  -0.613  1.00 31.55  ? 273 LEU D CA  1 
ATOM   12812 C C   . LEU D 1 273 ? 8.110   84.231  -1.153  1.00 30.76  ? 273 LEU D C   1 
ATOM   12813 O O   . LEU D 1 273 ? 8.487   84.963  -2.065  1.00 35.56  ? 273 LEU D O   1 
ATOM   12814 C CB  . LEU D 1 273 ? 6.433   85.847  -0.222  1.00 29.62  ? 273 LEU D CB  1 
ATOM   12815 C CG  . LEU D 1 273 ? 4.997   86.134  0.221   1.00 29.28  ? 273 LEU D CG  1 
ATOM   12816 C CD1 . LEU D 1 273 ? 4.754   87.586  0.545   1.00 28.96  ? 273 LEU D CD1 1 
ATOM   12817 C CD2 . LEU D 1 273 ? 4.081   85.647  -0.878  1.00 29.87  ? 273 LEU D CD2 1 
ATOM   12818 N N   . HIS D 1 274 ? 8.926   83.342  -0.586  1.00 29.25  ? 274 HIS D N   1 
ATOM   12819 C CA  . HIS D 1 274 ? 10.306  83.249  -1.048  1.00 28.31  ? 274 HIS D CA  1 
ATOM   12820 C C   . HIS D 1 274 ? 10.700  81.849  -1.498  1.00 25.91  ? 274 HIS D C   1 
ATOM   12821 O O   . HIS D 1 274 ? 11.423  81.717  -2.478  1.00 27.98  ? 274 HIS D O   1 
ATOM   12822 C CB  . HIS D 1 274 ? 11.311  83.736  -0.006  1.00 30.24  ? 274 HIS D CB  1 
ATOM   12823 C CG  . HIS D 1 274 ? 12.709  83.823  -0.532  1.00 30.71  ? 274 HIS D CG  1 
ATOM   12824 N ND1 . HIS D 1 274 ? 12.998  84.149  -1.834  1.00 32.34  ? 274 HIS D ND1 1 
ATOM   12825 C CD2 . HIS D 1 274 ? 13.901  83.635  0.061   1.00 32.25  ? 274 HIS D CD2 1 
ATOM   12826 C CE1 . HIS D 1 274 ? 14.321  84.151  -1.999  1.00 33.99  ? 274 HIS D CE1 1 
ATOM   12827 N NE2 . HIS D 1 274 ? 14.893  83.845  -0.864  1.00 30.88  ? 274 HIS D NE2 1 
ATOM   12828 N N   . GLY D 1 275 ? 10.189  80.815  -0.831  1.00 25.61  ? 275 GLY D N   1 
ATOM   12829 C CA  . GLY D 1 275 ? 10.733  79.487  -1.015  1.00 25.59  ? 275 GLY D CA  1 
ATOM   12830 C C   . GLY D 1 275 ? 9.706   78.399  -1.293  1.00 26.68  ? 275 GLY D C   1 
ATOM   12831 O O   . GLY D 1 275 ? 10.164  77.267  -1.456  1.00 25.86  ? 275 GLY D O   1 
ATOM   12832 N N   . LEU D 1 276 ? 8.387   78.708  -1.384  1.00 26.98  ? 276 LEU D N   1 
ATOM   12833 C CA  . LEU D 1 276 ? 7.381   77.646  -1.466  1.00 33.28  ? 276 LEU D CA  1 
ATOM   12834 C C   . LEU D 1 276 ? 6.840   77.437  -2.892  1.00 32.88  ? 276 LEU D C   1 
ATOM   12835 O O   . LEU D 1 276 ? 6.044   76.528  -3.127  1.00 28.26  ? 276 LEU D O   1 
ATOM   12836 C CB  . LEU D 1 276 ? 6.213   77.853  -0.501  1.00 42.42  ? 276 LEU D CB  1 
ATOM   12837 C CG  . LEU D 1 276 ? 6.576   78.099  0.969   1.00 57.34  ? 276 LEU D CG  1 
ATOM   12838 C CD1 . LEU D 1 276 ? 5.286   78.160  1.785   1.00 57.86  ? 276 LEU D CD1 1 
ATOM   12839 C CD2 . LEU D 1 276 ? 7.570   77.095  1.566   1.00 63.54  ? 276 LEU D CD2 1 
ATOM   12840 N N   . ALA D 1 277 ? 7.278   78.250  -3.856  1.00 31.18  ? 277 ALA D N   1 
ATOM   12841 C CA  . ALA D 1 277 ? 6.586   78.362  -5.131  1.00 29.61  ? 277 ALA D CA  1 
ATOM   12842 C C   . ALA D 1 277 ? 6.738   77.080  -5.933  1.00 29.67  ? 277 ALA D C   1 
ATOM   12843 O O   . ALA D 1 277 ? 5.803   76.683  -6.604  1.00 32.11  ? 277 ALA D O   1 
ATOM   12844 C CB  . ALA D 1 277 ? 7.080   79.566  -5.910  1.00 27.69  ? 277 ALA D CB  1 
ATOM   12845 N N   . ASN D 1 278 ? 7.920   76.458  -5.885  1.00 33.70  ? 278 ASN D N   1 
ATOM   12846 C CA  . ASN D 1 278 ? 8.136   75.152  -6.499  1.00 34.19  ? 278 ASN D CA  1 
ATOM   12847 C C   . ASN D 1 278 ? 6.924   74.251  -6.201  1.00 33.25  ? 278 ASN D C   1 
ATOM   12848 O O   . ASN D 1 278 ? 6.279   73.724  -7.106  1.00 30.24  ? 278 ASN D O   1 
ATOM   12849 C CB  . ASN D 1 278 ? 9.499   74.597  -6.080  1.00 31.07  ? 278 ASN D CB  1 
ATOM   12850 C CG  . ASN D 1 278 ? 9.697   73.131  -6.399  1.00 32.06  ? 278 ASN D CG  1 
ATOM   12851 O OD1 . ASN D 1 278 ? 10.748  72.560  -6.085  1.00 29.02  ? 278 ASN D OD1 1 
ATOM   12852 N ND2 . ASN D 1 278 ? 8.697   72.481  -6.979  1.00 33.95  ? 278 ASN D ND2 1 
ATOM   12853 N N   . GLN D 1 279 ? 6.617   74.121  -4.914  1.00 36.32  ? 279 GLN D N   1 
ATOM   12854 C CA  . GLN D 1 279 ? 5.613   73.215  -4.391  1.00 37.44  ? 279 GLN D CA  1 
ATOM   12855 C C   . GLN D 1 279 ? 4.226   73.586  -4.896  1.00 31.60  ? 279 GLN D C   1 
ATOM   12856 O O   . GLN D 1 279 ? 3.429   72.703  -5.160  1.00 30.12  ? 279 GLN D O   1 
ATOM   12857 C CB  . GLN D 1 279 ? 5.499   73.290  -2.864  1.00 42.67  ? 279 GLN D CB  1 
ATOM   12858 C CG  . GLN D 1 279 ? 6.687   72.696  -2.119  1.00 51.32  ? 279 GLN D CG  1 
ATOM   12859 C CD  . GLN D 1 279 ? 7.690   73.708  -1.593  1.00 54.46  ? 279 GLN D CD  1 
ATOM   12860 O OE1 . GLN D 1 279 ? 8.363   74.419  -2.358  1.00 55.41  ? 279 GLN D OE1 1 
ATOM   12861 N NE2 . GLN D 1 279 ? 7.851   73.718  -0.273  1.00 53.01  ? 279 GLN D NE2 1 
ATOM   12862 N N   . GLU D 1 280 ? 3.926   74.880  -4.929  1.00 32.93  ? 280 GLU D N   1 
ATOM   12863 C CA  . GLU D 1 280 ? 2.586   75.345  -5.245  1.00 41.83  ? 280 GLU D CA  1 
ATOM   12864 C C   . GLU D 1 280 ? 2.337   75.072  -6.729  1.00 38.88  ? 280 GLU D C   1 
ATOM   12865 O O   . GLU D 1 280 ? 1.224   74.710  -7.118  1.00 42.98  ? 280 GLU D O   1 
ATOM   12866 C CB  . GLU D 1 280 ? 2.382   76.812  -4.847  1.00 49.55  ? 280 GLU D CB  1 
ATOM   12867 C CG  . GLU D 1 280 ? 2.227   77.050  -3.344  1.00 56.40  ? 280 GLU D CG  1 
ATOM   12868 C CD  . GLU D 1 280 ? 2.743   78.404  -2.850  1.00 64.85  ? 280 GLU D CD  1 
ATOM   12869 O OE1 . GLU D 1 280 ? 2.710   78.633  -1.622  1.00 76.74  ? 280 GLU D OE1 1 
ATOM   12870 O OE2 . GLU D 1 280 ? 3.204   79.236  -3.658  1.00 65.06  ? 280 GLU D OE2 1 
ATOM   12871 N N   . VAL D 1 281 ? 3.402   75.171  -7.534  1.00 32.31  ? 281 VAL D N   1 
ATOM   12872 C CA  . VAL D 1 281 ? 3.327   74.811  -8.939  1.00 32.06  ? 281 VAL D CA  1 
ATOM   12873 C C   . VAL D 1 281 ? 2.991   73.325  -9.071  1.00 33.66  ? 281 VAL D C   1 
ATOM   12874 O O   . VAL D 1 281 ? 2.095   72.976  -9.835  1.00 33.62  ? 281 VAL D O   1 
ATOM   12875 C CB  . VAL D 1 281 ? 4.585   75.151  -9.754  1.00 27.81  ? 281 VAL D CB  1 
ATOM   12876 C CG1 . VAL D 1 281 ? 4.473   74.630  -11.173 1.00 26.98  ? 281 VAL D CG1 1 
ATOM   12877 C CG2 . VAL D 1 281 ? 4.837   76.646  -9.806  1.00 30.80  ? 281 VAL D CG2 1 
ATOM   12878 N N   . LEU D 1 282 ? 3.743   72.449  -8.391  1.00 32.80  ? 282 LEU D N   1 
ATOM   12879 C CA  . LEU D 1 282 ? 3.509   71.025  -8.548  1.00 33.78  ? 282 LEU D CA  1 
ATOM   12880 C C   . LEU D 1 282 ? 2.047   70.721  -8.205  1.00 31.50  ? 282 LEU D C   1 
ATOM   12881 O O   . LEU D 1 282 ? 1.376   70.002  -8.917  1.00 27.94  ? 282 LEU D O   1 
ATOM   12882 C CB  . LEU D 1 282 ? 4.481   70.202  -7.695  1.00 34.28  ? 282 LEU D CB  1 
ATOM   12883 C CG  . LEU D 1 282 ? 4.381   68.671  -7.829  1.00 33.24  ? 282 LEU D CG  1 
ATOM   12884 C CD1 . LEU D 1 282 ? 4.493   68.217  -9.268  1.00 35.33  ? 282 LEU D CD1 1 
ATOM   12885 C CD2 . LEU D 1 282 ? 5.445   67.942  -7.048  1.00 32.17  ? 282 LEU D CD2 1 
ATOM   12886 N N   . ARG D 1 283 ? 1.559   71.275  -7.099  1.00 32.55  ? 283 ARG D N   1 
ATOM   12887 C CA  . ARG D 1 283 ? 0.264   70.892  -6.562  1.00 37.04  ? 283 ARG D CA  1 
ATOM   12888 C C   . ARG D 1 283 ? -0.817  71.315  -7.560  1.00 36.67  ? 283 ARG D C   1 
ATOM   12889 O O   . ARG D 1 283 ? -1.781  70.588  -7.787  1.00 31.98  ? 283 ARG D O   1 
ATOM   12890 C CB  . ARG D 1 283 ? 0.076   71.472  -5.147  1.00 35.83  ? 283 ARG D CB  1 
ATOM   12891 C CG  . ARG D 1 283 ? 0.612   70.592  -4.027  1.00 39.73  ? 283 ARG D CG  1 
ATOM   12892 C CD  . ARG D 1 283 ? 0.515   71.257  -2.637  1.00 49.83  ? 283 ARG D CD  1 
ATOM   12893 N NE  . ARG D 1 283 ? 0.976   70.486  -1.465  1.00 53.91  ? 283 ARG D NE  1 
ATOM   12894 C CZ  . ARG D 1 283 ? 0.529   69.284  -1.040  1.00 55.74  ? 283 ARG D CZ  1 
ATOM   12895 N NH1 . ARG D 1 283 ? 0.978   68.784  0.093   1.00 50.99  ? 283 ARG D NH1 1 
ATOM   12896 N NH2 . ARG D 1 283 ? -0.367  68.570  -1.713  1.00 53.65  ? 283 ARG D NH2 1 
ATOM   12897 N N   . TRP D 1 284 ? -0.623  72.511  -8.122  1.00 35.16  ? 284 TRP D N   1 
ATOM   12898 C CA  . TRP D 1 284 ? -1.478  73.078  -9.145  1.00 36.82  ? 284 TRP D CA  1 
ATOM   12899 C C   . TRP D 1 284 ? -1.433  72.255  -10.429 1.00 35.88  ? 284 TRP D C   1 
ATOM   12900 O O   . TRP D 1 284 ? -2.490  72.045  -11.030 1.00 38.39  ? 284 TRP D O   1 
ATOM   12901 C CB  . TRP D 1 284 ? -1.016  74.513  -9.392  1.00 39.05  ? 284 TRP D CB  1 
ATOM   12902 C CG  . TRP D 1 284 ? -1.867  75.364  -10.288 1.00 44.33  ? 284 TRP D CG  1 
ATOM   12903 C CD1 . TRP D 1 284 ? -2.886  76.205  -9.928  1.00 45.57  ? 284 TRP D CD1 1 
ATOM   12904 C CD2 . TRP D 1 284 ? -1.676  75.541  -11.702 1.00 42.75  ? 284 TRP D CD2 1 
ATOM   12905 N NE1 . TRP D 1 284 ? -3.358  76.878  -11.023 1.00 43.23  ? 284 TRP D NE1 1 
ATOM   12906 C CE2 . TRP D 1 284 ? -2.636  76.486  -12.125 1.00 45.62  ? 284 TRP D CE2 1 
ATOM   12907 C CE3 . TRP D 1 284 ? -0.809  74.980  -12.639 1.00 43.01  ? 284 TRP D CE3 1 
ATOM   12908 C CZ2 . TRP D 1 284 ? -2.737  76.881  -13.456 1.00 44.78  ? 284 TRP D CZ2 1 
ATOM   12909 C CZ3 . TRP D 1 284 ? -0.918  75.367  -13.954 1.00 42.19  ? 284 TRP D CZ3 1 
ATOM   12910 C CH2 . TRP D 1 284 ? -1.862  76.311  -14.351 1.00 44.14  ? 284 TRP D CH2 1 
ATOM   12911 N N   . ILE D 1 285 ? -0.241  71.767  -10.825 1.00 31.23  ? 285 ILE D N   1 
ATOM   12912 C CA  . ILE D 1 285 ? -0.128  70.858  -11.968 1.00 33.64  ? 285 ILE D CA  1 
ATOM   12913 C C   . ILE D 1 285 ? -0.867  69.544  -11.680 1.00 34.17  ? 285 ILE D C   1 
ATOM   12914 O O   . ILE D 1 285 ? -1.566  69.030  -12.555 1.00 31.52  ? 285 ILE D O   1 
ATOM   12915 C CB  . ILE D 1 285 ? 1.340   70.593  -12.361 1.00 30.84  ? 285 ILE D CB  1 
ATOM   12916 C CG1 . ILE D 1 285 ? 2.011   71.828  -12.892 1.00 35.94  ? 285 ILE D CG1 1 
ATOM   12917 C CG2 . ILE D 1 285 ? 1.496   69.435  -13.342 1.00 30.28  ? 285 ILE D CG2 1 
ATOM   12918 C CD1 . ILE D 1 285 ? 1.501   72.296  -14.237 1.00 40.19  ? 285 ILE D CD1 1 
ATOM   12919 N N   . GLN D 1 286 ? -0.696  68.993  -10.468 1.00 33.98  ? 286 GLN D N   1 
ATOM   12920 C CA  . GLN D 1 286 ? -1.360  67.754  -10.070 1.00 34.14  ? 286 GLN D CA  1 
ATOM   12921 C C   . GLN D 1 286 ? -2.889  67.915  -10.001 1.00 35.59  ? 286 GLN D C   1 
ATOM   12922 O O   . GLN D 1 286 ? -3.636  66.971  -10.275 1.00 30.31  ? 286 GLN D O   1 
ATOM   12923 C CB  . GLN D 1 286 ? -0.771  67.261  -8.752  1.00 30.93  ? 286 GLN D CB  1 
ATOM   12924 C CG  . GLN D 1 286 ? 0.684   66.845  -8.876  1.00 29.35  ? 286 GLN D CG  1 
ATOM   12925 C CD  . GLN D 1 286 ? 1.291   66.359  -7.584  1.00 31.76  ? 286 GLN D CD  1 
ATOM   12926 O OE1 . GLN D 1 286 ? 1.882   65.269  -7.511  1.00 32.05  ? 286 GLN D OE1 1 
ATOM   12927 N NE2 . GLN D 1 286 ? 1.191   67.196  -6.560  1.00 32.60  ? 286 GLN D NE2 1 
ATOM   12928 N N   . MET D 1 287 ? -3.360  69.112  -9.631  1.00 38.78  ? 287 MET D N   1 
ATOM   12929 C CA  . MET D 1 287 ? -4.780  69.413  -9.586  1.00 42.59  ? 287 MET D CA  1 
ATOM   12930 C C   . MET D 1 287 ? -5.379  69.331  -10.992 1.00 42.18  ? 287 MET D C   1 
ATOM   12931 O O   . MET D 1 287 ? -6.401  68.688  -11.169 1.00 42.92  ? 287 MET D O   1 
ATOM   12932 C CB  . MET D 1 287 ? -5.001  70.795  -8.966  1.00 50.01  ? 287 MET D CB  1 
ATOM   12933 C CG  . MET D 1 287 ? -6.434  71.087  -8.563  1.00 60.65  ? 287 MET D CG  1 
ATOM   12934 S SD  . MET D 1 287 ? -6.555  71.792  -6.902  1.00 78.28  ? 287 MET D SD  1 
ATOM   12935 C CE  . MET D 1 287 ? -6.403  70.343  -5.840  1.00 79.62  ? 287 MET D CE  1 
ATOM   12936 N N   . LEU D 1 288 ? -4.718  69.948  -11.979 1.00 41.67  ? 288 LEU D N   1 
ATOM   12937 C CA  . LEU D 1 288 ? -5.097  69.868  -13.386 1.00 43.44  ? 288 LEU D CA  1 
ATOM   12938 C C   . LEU D 1 288 ? -5.190  68.433  -13.893 1.00 41.84  ? 288 LEU D C   1 
ATOM   12939 O O   . LEU D 1 288 ? -6.079  68.094  -14.661 1.00 42.56  ? 288 LEU D O   1 
ATOM   12940 C CB  . LEU D 1 288 ? -4.074  70.585  -14.254 1.00 41.30  ? 288 LEU D CB  1 
ATOM   12941 C CG  . LEU D 1 288 ? -4.293  72.079  -14.414 1.00 43.23  ? 288 LEU D CG  1 
ATOM   12942 C CD1 . LEU D 1 288 ? -3.001  72.794  -14.710 1.00 44.61  ? 288 LEU D CD1 1 
ATOM   12943 C CD2 . LEU D 1 288 ? -5.307  72.269  -15.518 1.00 50.28  ? 288 LEU D CD2 1 
ATOM   12944 N N   . TYR D 1 289 ? -4.195  67.634  -13.558 1.00 41.70  ? 289 TYR D N   1 
ATOM   12945 C CA  . TYR D 1 289 ? -4.119  66.285  -14.075 1.00 41.99  ? 289 TYR D CA  1 
ATOM   12946 C C   . TYR D 1 289 ? -5.250  65.439  -13.490 1.00 40.48  ? 289 TYR D C   1 
ATOM   12947 O O   . TYR D 1 289 ? -5.760  64.552  -14.154 1.00 42.96  ? 289 TYR D O   1 
ATOM   12948 C CB  . TYR D 1 289 ? -2.710  65.810  -13.720 1.00 42.13  ? 289 TYR D CB  1 
ATOM   12949 C CG  . TYR D 1 289 ? -2.445  64.376  -14.132 1.00 52.29  ? 289 TYR D CG  1 
ATOM   12950 C CD1 . TYR D 1 289 ? -2.106  64.079  -15.449 1.00 52.86  ? 289 TYR D CD1 1 
ATOM   12951 C CD2 . TYR D 1 289 ? -2.514  63.334  -13.214 1.00 61.18  ? 289 TYR D CD2 1 
ATOM   12952 C CE1 . TYR D 1 289 ? -1.838  62.782  -15.843 1.00 60.97  ? 289 TYR D CE1 1 
ATOM   12953 C CE2 . TYR D 1 289 ? -2.252  62.029  -13.601 1.00 75.38  ? 289 TYR D CE2 1 
ATOM   12954 C CZ  . TYR D 1 289 ? -1.921  61.753  -14.922 1.00 74.09  ? 289 TYR D CZ  1 
ATOM   12955 O OH  . TYR D 1 289 ? -1.671  60.483  -15.363 1.00 72.26  ? 289 TYR D OH  1 
ATOM   12956 N N   . LYS D 1 290 ? -5.622  65.696  -12.234 1.00 42.34  ? 290 LYS D N   1 
ATOM   12957 C CA  . LYS D 1 290 ? -6.656  64.938  -11.544 1.00 45.83  ? 290 LYS D CA  1 
ATOM   12958 C C   . LYS D 1 290 ? -8.007  65.238  -12.195 1.00 47.10  ? 290 LYS D C   1 
ATOM   12959 O O   . LYS D 1 290 ? -8.736  64.308  -12.574 1.00 42.32  ? 290 LYS D O   1 
ATOM   12960 C CB  . LYS D 1 290 ? -6.669  65.343  -10.060 1.00 58.30  ? 290 LYS D CB  1 
ATOM   12961 C CG  . LYS D 1 290 ? -7.560  64.559  -9.054  1.00 67.00  ? 290 LYS D CG  1 
ATOM   12962 C CD  . LYS D 1 290 ? -6.890  63.500  -8.167  1.00 75.46  ? 290 LYS D CD  1 
ATOM   12963 C CE  . LYS D 1 290 ? -5.857  64.012  -7.174  1.00 79.19  ? 290 LYS D CE  1 
ATOM   12964 N NZ  . LYS D 1 290 ? -5.417  63.006  -6.196  1.00 77.65  ? 290 LYS D NZ  1 
ATOM   12965 N N   . LYS D 1 291 ? -8.287  66.550  -12.341 1.00 41.62  ? 291 LYS D N   1 
ATOM   12966 C CA  . LYS D 1 291 ? -9.556  67.070  -12.818 1.00 42.45  ? 291 LYS D CA  1 
ATOM   12967 C C   . LYS D 1 291 ? -9.897  66.484  -14.181 1.00 43.86  ? 291 LYS D C   1 
ATOM   12968 O O   . LYS D 1 291 ? -11.023 66.012  -14.354 1.00 38.26  ? 291 LYS D O   1 
ATOM   12969 C CB  . LYS D 1 291 ? -9.511  68.593  -12.950 1.00 45.73  ? 291 LYS D CB  1 
ATOM   12970 C CG  . LYS D 1 291 ? -10.839 69.271  -13.292 1.00 46.42  ? 291 LYS D CG  1 
ATOM   12971 C CD  . LYS D 1 291 ? -10.933 70.653  -12.657 1.00 50.89  ? 291 LYS D CD  1 
ATOM   12972 C CE  . LYS D 1 291 ? -11.851 71.598  -13.356 1.00 55.15  ? 291 LYS D CE  1 
ATOM   12973 N NZ  . LYS D 1 291 ? -13.252 71.207  -13.216 1.00 56.70  ? 291 LYS D NZ  1 
ATOM   12974 N N   . PHE D 1 292 ? -8.900  66.507  -15.094 1.00 40.24  ? 292 PHE D N   1 
ATOM   12975 C CA  . PHE D 1 292 ? -9.059  66.127  -16.488 1.00 36.99  ? 292 PHE D CA  1 
ATOM   12976 C C   . PHE D 1 292 ? -8.522  64.724  -16.783 1.00 41.62  ? 292 PHE D C   1 
ATOM   12977 O O   . PHE D 1 292 ? -8.385  64.357  -17.939 1.00 48.56  ? 292 PHE D O   1 
ATOM   12978 C CB  . PHE D 1 292 ? -8.344  67.167  -17.348 1.00 34.02  ? 292 PHE D CB  1 
ATOM   12979 C CG  . PHE D 1 292 ? -8.899  68.570  -17.210 1.00 32.42  ? 292 PHE D CG  1 
ATOM   12980 C CD1 . PHE D 1 292 ? -10.214 68.843  -17.573 1.00 31.15  ? 292 PHE D CD1 1 
ATOM   12981 C CD2 . PHE D 1 292 ? -8.111  69.608  -16.725 1.00 33.47  ? 292 PHE D CD2 1 
ATOM   12982 C CE1 . PHE D 1 292 ? -10.730 70.127  -17.440 1.00 33.34  ? 292 PHE D CE1 1 
ATOM   12983 C CE2 . PHE D 1 292 ? -8.627  70.898  -16.597 1.00 35.28  ? 292 PHE D CE2 1 
ATOM   12984 C CZ  . PHE D 1 292 ? -9.940  71.160  -16.954 1.00 34.65  ? 292 PHE D CZ  1 
ATOM   12985 N N   . GLY D 1 293 ? -8.259  63.899  -15.770 1.00 44.73  ? 293 GLY D N   1 
ATOM   12986 C CA  . GLY D 1 293 ? -7.929  62.501  -16.020 1.00 46.17  ? 293 GLY D CA  1 
ATOM   12987 C C   . GLY D 1 293 ? -6.745  62.349  -16.976 1.00 49.79  ? 293 GLY D C   1 
ATOM   12988 O O   . GLY D 1 293 ? -6.661  61.363  -17.707 1.00 54.02  ? 293 GLY D O   1 
ATOM   12989 N N   . GLY D 1 294 ? -5.835  63.335  -16.972 1.00 46.26  ? 294 GLY D N   1 
ATOM   12990 C CA  . GLY D 1 294 ? -4.616  63.283  -17.769 1.00 45.41  ? 294 GLY D CA  1 
ATOM   12991 C C   . GLY D 1 294 ? -4.176  64.676  -18.213 1.00 41.66  ? 294 GLY D C   1 
ATOM   12992 O O   . GLY D 1 294 ? -4.540  65.669  -17.585 1.00 41.75  ? 294 GLY D O   1 
ATOM   12993 N N   . VAL D 1 295 ? -3.461  64.734  -19.345 1.00 38.42  ? 295 VAL D N   1 
ATOM   12994 C CA  . VAL D 1 295 ? -3.011  65.994  -19.920 1.00 37.81  ? 295 VAL D CA  1 
ATOM   12995 C C   . VAL D 1 295 ? -4.220  66.730  -20.493 1.00 37.35  ? 295 VAL D C   1 
ATOM   12996 O O   . VAL D 1 295 ? -4.869  66.233  -21.403 1.00 37.05  ? 295 VAL D O   1 
ATOM   12997 C CB  . VAL D 1 295 ? -1.940  65.827  -21.021 1.00 39.10  ? 295 VAL D CB  1 
ATOM   12998 C CG1 . VAL D 1 295 ? -1.416  67.172  -21.511 1.00 36.17  ? 295 VAL D CG1 1 
ATOM   12999 C CG2 . VAL D 1 295 ? -0.773  64.949  -20.578 1.00 43.20  ? 295 VAL D CG2 1 
ATOM   13000 N N   . PRO D 1 296 ? -4.502  67.980  -20.070 1.00 37.83  ? 296 PRO D N   1 
ATOM   13001 C CA  . PRO D 1 296 ? -5.605  68.744  -20.640 1.00 38.19  ? 296 PRO D CA  1 
ATOM   13002 C C   . PRO D 1 296 ? -5.356  69.229  -22.059 1.00 36.64  ? 296 PRO D C   1 
ATOM   13003 O O   . PRO D 1 296 ? -4.218  69.412  -22.477 1.00 36.62  ? 296 PRO D O   1 
ATOM   13004 C CB  . PRO D 1 296 ? -5.659  69.952  -19.677 1.00 40.65  ? 296 PRO D CB  1 
ATOM   13005 C CG  . PRO D 1 296 ? -4.209  70.203  -19.371 1.00 38.36  ? 296 PRO D CG  1 
ATOM   13006 C CD  . PRO D 1 296 ? -3.729  68.775  -19.101 1.00 40.61  ? 296 PRO D CD  1 
ATOM   13007 N N   . THR D 1 297 ? -6.456  69.555  -22.730 1.00 37.40  ? 297 THR D N   1 
ATOM   13008 C CA  . THR D 1 297 ? -6.433  70.285  -23.985 1.00 36.39  ? 297 THR D CA  1 
ATOM   13009 C C   . THR D 1 297 ? -6.081  71.734  -23.673 1.00 34.18  ? 297 THR D C   1 
ATOM   13010 O O   . THR D 1 297 ? -6.086  72.130  -22.514 1.00 32.14  ? 297 THR D O   1 
ATOM   13011 C CB  . THR D 1 297 ? -7.797  70.146  -24.668 1.00 35.15  ? 297 THR D CB  1 
ATOM   13012 O OG1 . THR D 1 297 ? -8.687  71.038  -23.985 1.00 37.79  ? 297 THR D OG1 1 
ATOM   13013 C CG2 . THR D 1 297 ? -8.278  68.701  -24.676 1.00 30.51  ? 297 THR D CG2 1 
ATOM   13014 N N   . LYS D 1 298 ? -5.747  72.500  -24.709 1.00 37.09  ? 298 LYS D N   1 
ATOM   13015 C CA  . LYS D 1 298 ? -5.391  73.894  -24.533 1.00 43.96  ? 298 LYS D CA  1 
ATOM   13016 C C   . LYS D 1 298 ? -6.592  74.657  -24.002 1.00 48.23  ? 298 LYS D C   1 
ATOM   13017 O O   . LYS D 1 298 ? -6.423  75.680  -23.342 1.00 55.33  ? 298 LYS D O   1 
ATOM   13018 C CB  . LYS D 1 298 ? -4.955  74.604  -25.816 1.00 47.75  ? 298 LYS D CB  1 
ATOM   13019 C CG  . LYS D 1 298 ? -3.554  74.282  -26.299 1.00 58.74  ? 298 LYS D CG  1 
ATOM   13020 C CD  . LYS D 1 298 ? -3.071  75.206  -27.414 1.00 62.09  ? 298 LYS D CD  1 
ATOM   13021 C CE  . LYS D 1 298 ? -1.629  74.964  -27.747 1.00 64.96  ? 298 LYS D CE  1 
ATOM   13022 N NZ  . LYS D 1 298 ? -1.237  75.664  -28.973 1.00 68.70  ? 298 LYS D NZ  1 
ATOM   13023 N N   . GLU D 1 299 ? -7.792  74.166  -24.338 1.00 52.53  ? 299 GLU D N   1 
ATOM   13024 C CA  . GLU D 1 299 ? -9.024  74.803  -23.910 1.00 55.66  ? 299 GLU D CA  1 
ATOM   13025 C C   . GLU D 1 299 ? -9.215  74.543  -22.414 1.00 45.51  ? 299 GLU D C   1 
ATOM   13026 O O   . GLU D 1 299 ? -9.484  75.473  -21.654 1.00 40.45  ? 299 GLU D O   1 
ATOM   13027 C CB  . GLU D 1 299 ? -10.195 74.317  -24.769 1.00 68.50  ? 299 GLU D CB  1 
ATOM   13028 C CG  . GLU D 1 299 ? -11.399 75.265  -24.771 1.00 83.73  ? 299 GLU D CG  1 
ATOM   13029 C CD  . GLU D 1 299 ? -12.658 74.811  -24.032 1.00 88.15  ? 299 GLU D CD  1 
ATOM   13030 O OE1 . GLU D 1 299 ? -13.280 73.887  -24.601 1.00 83.43  ? 299 GLU D OE1 1 
ATOM   13031 O OE2 . GLU D 1 299 ? -13.043 75.356  -22.955 1.00 86.52  ? 299 GLU D OE2 1 
ATOM   13032 N N   . GLN D 1 300 ? -9.073  73.277  -22.004 1.00 37.90  ? 300 GLN D N   1 
ATOM   13033 C CA  . GLN D 1 300 ? -9.295  72.891  -20.623 1.00 37.75  ? 300 GLN D CA  1 
ATOM   13034 C C   . GLN D 1 300 ? -8.330  73.639  -19.707 1.00 41.36  ? 300 GLN D C   1 
ATOM   13035 O O   . GLN D 1 300 ? -8.734  74.149  -18.667 1.00 43.77  ? 300 GLN D O   1 
ATOM   13036 C CB  . GLN D 1 300 ? -9.135  71.380  -20.501 1.00 38.46  ? 300 GLN D CB  1 
ATOM   13037 C CG  . GLN D 1 300 ? -10.236 70.561  -21.168 1.00 36.10  ? 300 GLN D CG  1 
ATOM   13038 C CD  . GLN D 1 300 ? -9.981  69.063  -21.117 1.00 39.14  ? 300 GLN D CD  1 
ATOM   13039 O OE1 . GLN D 1 300 ? -8.839  68.582  -21.168 1.00 45.07  ? 300 GLN D OE1 1 
ATOM   13040 N NE2 . GLN D 1 300 ? -11.043 68.281  -21.008 1.00 37.52  ? 300 GLN D NE2 1 
ATOM   13041 N N   . LEU D 1 301 ? -7.061  73.742  -20.124 1.00 48.26  ? 301 LEU D N   1 
ATOM   13042 C CA  . LEU D 1 301 ? -6.032  74.454  -19.376 1.00 48.03  ? 301 LEU D CA  1 
ATOM   13043 C C   . LEU D 1 301 ? -6.346  75.946  -19.236 1.00 51.86  ? 301 LEU D C   1 
ATOM   13044 O O   . LEU D 1 301 ? -6.159  76.511  -18.159 1.00 53.46  ? 301 LEU D O   1 
ATOM   13045 C CB  . LEU D 1 301 ? -4.688  74.263  -20.063 1.00 47.39  ? 301 LEU D CB  1 
ATOM   13046 C CG  . LEU D 1 301 ? -3.501  74.922  -19.363 1.00 48.51  ? 301 LEU D CG  1 
ATOM   13047 C CD1 . LEU D 1 301 ? -3.209  74.145  -18.090 1.00 51.66  ? 301 LEU D CD1 1 
ATOM   13048 C CD2 . LEU D 1 301 ? -2.284  74.953  -20.267 1.00 51.84  ? 301 LEU D CD2 1 
ATOM   13049 N N   . GLU D 1 302 ? -6.785  76.599  -20.322 1.00 54.44  ? 302 GLU D N   1 
ATOM   13050 C CA  . GLU D 1 302 ? -7.115  78.019  -20.281 1.00 56.53  ? 302 GLU D CA  1 
ATOM   13051 C C   . GLU D 1 302 ? -8.254  78.305  -19.288 1.00 55.70  ? 302 GLU D C   1 
ATOM   13052 O O   . GLU D 1 302 ? -8.170  79.239  -18.488 1.00 46.58  ? 302 GLU D O   1 
ATOM   13053 C CB  . GLU D 1 302 ? -7.406  78.513  -21.697 1.00 58.97  ? 302 GLU D CB  1 
ATOM   13054 C CG  . GLU D 1 302 ? -7.737  80.005  -21.738 1.00 63.21  ? 302 GLU D CG  1 
ATOM   13055 C CD  . GLU D 1 302 ? -7.602  80.683  -23.088 1.00 64.31  ? 302 GLU D CD  1 
ATOM   13056 O OE1 . GLU D 1 302 ? -7.714  81.935  -23.098 1.00 56.60  ? 302 GLU D OE1 1 
ATOM   13057 O OE2 . GLU D 1 302 ? -7.370  79.966  -24.098 1.00 59.61  ? 302 GLU D OE2 1 
ATOM   13058 N N   . ARG D 1 303 ? -9.321  77.495  -19.337 1.00 63.76  ? 303 ARG D N   1 
ATOM   13059 C CA  . ARG D 1 303 ? -10.435 77.601  -18.400 1.00 62.65  ? 303 ARG D CA  1 
ATOM   13060 C C   . ARG D 1 303 ? -9.913  77.517  -16.961 1.00 53.96  ? 303 ARG D C   1 
ATOM   13061 O O   . ARG D 1 303 ? -10.158 78.414  -16.155 1.00 48.85  ? 303 ARG D O   1 
ATOM   13062 C CB  . ARG D 1 303 ? -11.491 76.527  -18.708 1.00 68.87  ? 303 ARG D CB  1 
ATOM   13063 C CG  . ARG D 1 303 ? -12.875 76.773  -18.113 1.00 82.85  ? 303 ARG D CG  1 
ATOM   13064 C CD  . ARG D 1 303 ? -13.952 75.821  -18.653 1.00 89.33  ? 303 ARG D CD  1 
ATOM   13065 N NE  . ARG D 1 303 ? -13.759 74.423  -18.234 1.00 93.25  ? 303 ARG D NE  1 
ATOM   13066 C CZ  . ARG D 1 303 ? -13.595 73.352  -19.025 1.00 96.11  ? 303 ARG D CZ  1 
ATOM   13067 N NH1 . ARG D 1 303 ? -13.501 72.140  -18.494 1.00 87.52  ? 303 ARG D NH1 1 
ATOM   13068 N NH2 . ARG D 1 303 ? -13.541 73.483  -20.344 1.00 98.54  ? 303 ARG D NH2 1 
ATOM   13069 N N   . PHE D 1 304 ? -9.144  76.463  -16.661 1.00 47.79  ? 304 PHE D N   1 
ATOM   13070 C CA  . PHE D 1 304 ? -8.613  76.234  -15.323 1.00 47.31  ? 304 PHE D CA  1 
ATOM   13071 C C   . PHE D 1 304 ? -7.721  77.385  -14.875 1.00 42.35  ? 304 PHE D C   1 
ATOM   13072 O O   . PHE D 1 304 ? -7.674  77.676  -13.692 1.00 39.82  ? 304 PHE D O   1 
ATOM   13073 C CB  . PHE D 1 304 ? -7.777  74.957  -15.257 1.00 51.51  ? 304 PHE D CB  1 
ATOM   13074 C CG  . PHE D 1 304 ? -7.336  74.561  -13.855 1.00 53.93  ? 304 PHE D CG  1 
ATOM   13075 C CD1 . PHE D 1 304 ? -8.176  73.814  -13.031 1.00 54.31  ? 304 PHE D CD1 1 
ATOM   13076 C CD2 . PHE D 1 304 ? -6.078  74.920  -13.369 1.00 48.34  ? 304 PHE D CD2 1 
ATOM   13077 C CE1 . PHE D 1 304 ? -7.760  73.430  -11.763 1.00 52.68  ? 304 PHE D CE1 1 
ATOM   13078 C CE2 . PHE D 1 304 ? -5.670  74.534  -12.104 1.00 45.93  ? 304 PHE D CE2 1 
ATOM   13079 C CZ  . PHE D 1 304 ? -6.509  73.788  -11.303 1.00 49.87  ? 304 PHE D CZ  1 
ATOM   13080 N N   . ALA D 1 305 ? -7.016  78.023  -15.821 1.00 45.47  ? 305 ALA D N   1 
ATOM   13081 C CA  . ALA D 1 305 ? -6.192  79.195  -15.530 1.00 45.28  ? 305 ALA D CA  1 
ATOM   13082 C C   . ALA D 1 305 ? -7.082  80.389  -15.181 1.00 42.82  ? 305 ALA D C   1 
ATOM   13083 O O   . ALA D 1 305 ? -6.820  81.105  -14.210 1.00 37.71  ? 305 ALA D O   1 
ATOM   13084 C CB  . ALA D 1 305 ? -5.256  79.523  -16.693 1.00 44.37  ? 305 ALA D CB  1 
ATOM   13085 N N   . TRP D 1 306 ? -8.132  80.605  -15.984 1.00 41.73  ? 306 TRP D N   1 
ATOM   13086 C CA  . TRP D 1 306 ? -9.062  81.690  -15.698 1.00 42.27  ? 306 TRP D CA  1 
ATOM   13087 C C   . TRP D 1 306 ? -9.763  81.477  -14.350 1.00 37.41  ? 306 TRP D C   1 
ATOM   13088 O O   . TRP D 1 306 ? -9.771  82.408  -13.545 1.00 32.41  ? 306 TRP D O   1 
ATOM   13089 C CB  . TRP D 1 306 ? -10.030 81.887  -16.871 1.00 40.81  ? 306 TRP D CB  1 
ATOM   13090 C CG  . TRP D 1 306 ? -9.371  82.514  -18.076 1.00 37.10  ? 306 TRP D CG  1 
ATOM   13091 C CD1 . TRP D 1 306 ? -9.161  81.952  -19.302 1.00 33.82  ? 306 TRP D CD1 1 
ATOM   13092 C CD2 . TRP D 1 306 ? -8.801  83.838  -18.146 1.00 35.21  ? 306 TRP D CD2 1 
ATOM   13093 N NE1 . TRP D 1 306 ? -8.527  82.836  -20.138 1.00 36.35  ? 306 TRP D NE1 1 
ATOM   13094 C CE2 . TRP D 1 306 ? -8.290  84.000  -19.456 1.00 36.34  ? 306 TRP D CE2 1 
ATOM   13095 C CE3 . TRP D 1 306 ? -8.686  84.889  -17.238 1.00 35.70  ? 306 TRP D CE3 1 
ATOM   13096 C CZ2 . TRP D 1 306 ? -7.674  85.173  -19.874 1.00 36.27  ? 306 TRP D CZ2 1 
ATOM   13097 C CZ3 . TRP D 1 306 ? -8.063  86.047  -17.641 1.00 37.44  ? 306 TRP D CZ3 1 
ATOM   13098 C CH2 . TRP D 1 306 ? -7.565  86.181  -18.942 1.00 40.50  ? 306 TRP D CH2 1 
ATOM   13099 N N   . ASP D 1 307 ? -10.247 80.248  -14.078 1.00 37.25  ? 307 ASP D N   1 
ATOM   13100 C CA  . ASP D 1 307 ? -10.833 79.874  -12.786 1.00 42.53  ? 307 ASP D CA  1 
ATOM   13101 C C   . ASP D 1 307 ? -9.867  80.093  -11.606 1.00 46.99  ? 307 ASP D C   1 
ATOM   13102 O O   . ASP D 1 307 ? -10.307 80.464  -10.514 1.00 38.47  ? 307 ASP D O   1 
ATOM   13103 C CB  . ASP D 1 307 ? -11.334 78.433  -12.764 1.00 40.71  ? 307 ASP D CB  1 
ATOM   13104 C CG  . ASP D 1 307 ? -12.489 78.111  -13.708 1.00 45.43  ? 307 ASP D CG  1 
ATOM   13105 O OD1 . ASP D 1 307 ? -13.144 79.072  -14.192 1.00 46.66  ? 307 ASP D OD1 1 
ATOM   13106 O OD2 . ASP D 1 307 ? -12.702 76.903  -13.990 1.00 42.06  ? 307 ASP D OD2 1 
ATOM   13107 N N   . THR D 1 308 ? -8.554  79.870  -11.822 1.00 47.45  ? 308 THR D N   1 
ATOM   13108 C CA  . THR D 1 308 ? -7.538  80.170  -10.821 1.00 42.37  ? 308 THR D CA  1 
ATOM   13109 C C   . THR D 1 308 ? -7.526  81.666  -10.527 1.00 38.94  ? 308 THR D C   1 
ATOM   13110 O O   . THR D 1 308 ? -7.617  82.046  -9.371  1.00 42.26  ? 308 THR D O   1 
ATOM   13111 C CB  . THR D 1 308 ? -6.157  79.678  -11.261 1.00 43.12  ? 308 THR D CB  1 
ATOM   13112 O OG1 . THR D 1 308 ? -6.163  78.255  -11.226 1.00 41.55  ? 308 THR D OG1 1 
ATOM   13113 C CG2 . THR D 1 308 ? -5.033  80.167  -10.360 1.00 41.55  ? 308 THR D CG2 1 
ATOM   13114 N N   . LEU D 1 309 ? -7.444  82.512  -11.557 1.00 38.29  ? 309 LEU D N   1 
ATOM   13115 C CA  . LEU D 1 309 ? -7.395  83.956  -11.363 1.00 44.43  ? 309 LEU D CA  1 
ATOM   13116 C C   . LEU D 1 309 ? -8.695  84.541  -10.789 1.00 52.16  ? 309 LEU D C   1 
ATOM   13117 O O   . LEU D 1 309 ? -8.627  85.481  -10.009 1.00 52.92  ? 309 LEU D O   1 
ATOM   13118 C CB  . LEU D 1 309 ? -7.063  84.593  -12.706 1.00 44.60  ? 309 LEU D CB  1 
ATOM   13119 C CG  . LEU D 1 309 ? -5.695  84.248  -13.291 1.00 45.19  ? 309 LEU D CG  1 
ATOM   13120 C CD1 . LEU D 1 309 ? -5.597  84.644  -14.775 1.00 44.02  ? 309 LEU D CD1 1 
ATOM   13121 C CD2 . LEU D 1 309 ? -4.624  84.931  -12.455 1.00 45.97  ? 309 LEU D CD2 1 
ATOM   13122 N N   . ASN D 1 310 ? -9.875  84.035  -11.191 1.00 59.56  ? 310 ASN D N   1 
ATOM   13123 C CA  . ASN D 1 310 ? -11.156 84.585  -10.736 1.00 60.20  ? 310 ASN D CA  1 
ATOM   13124 C C   . ASN D 1 310 ? -11.399 84.276  -9.257  1.00 65.92  ? 310 ASN D C   1 
ATOM   13125 O O   . ASN D 1 310 ? -12.108 85.009  -8.569  1.00 67.52  ? 310 ASN D O   1 
ATOM   13126 C CB  . ASN D 1 310 ? -12.372 84.011  -11.460 1.00 51.12  ? 310 ASN D CB  1 
ATOM   13127 C CG  . ASN D 1 310 ? -12.275 84.133  -12.960 1.00 54.91  ? 310 ASN D CG  1 
ATOM   13128 O OD1 . ASN D 1 310 ? -12.835 83.300  -13.685 1.00 53.90  ? 310 ASN D OD1 1 
ATOM   13129 N ND2 . ASN D 1 310 ? -11.526 85.113  -13.444 1.00 56.54  ? 310 ASN D ND2 1 
ATOM   13130 N N   . SER D 1 311 ? -10.837 83.159  -8.781  1.00 62.68  ? 311 SER D N   1 
ATOM   13131 C CA  . SER D 1 311 ? -10.957 82.786  -7.384  1.00 57.94  ? 311 SER D CA  1 
ATOM   13132 C C   . SER D 1 311 ? -9.920  83.533  -6.537  1.00 58.60  ? 311 SER D C   1 
ATOM   13133 O O   . SER D 1 311 ? -9.761  83.223  -5.361  1.00 54.15  ? 311 SER D O   1 
ATOM   13134 C CB  . SER D 1 311 ? -10.866 81.290  -7.223  1.00 51.73  ? 311 SER D CB  1 
ATOM   13135 O OG  . SER D 1 311 ? -9.526  80.853  -7.378  1.00 57.86  ? 311 SER D OG  1 
ATOM   13136 N N   . GLY D 1 312 ? -9.220  84.513  -7.142  1.00 63.68  ? 312 GLY D N   1 
ATOM   13137 C CA  . GLY D 1 312 ? -8.346  85.444  -6.429  1.00 63.77  ? 312 GLY D CA  1 
ATOM   13138 C C   . GLY D 1 312 ? -6.919  84.919  -6.222  1.00 63.97  ? 312 GLY D C   1 
ATOM   13139 O O   . GLY D 1 312 ? -6.187  85.383  -5.352  1.00 57.20  ? 312 GLY D O   1 
ATOM   13140 N N   . GLN D 1 313 ? -6.510  83.947  -7.034  1.00 63.01  ? 313 GLN D N   1 
ATOM   13141 C CA  . GLN D 1 313 ? -5.223  83.304  -6.861  1.00 50.70  ? 313 GLN D CA  1 
ATOM   13142 C C   . GLN D 1 313 ? -4.302  83.751  -7.984  1.00 45.62  ? 313 GLN D C   1 
ATOM   13143 O O   . GLN D 1 313 ? -4.749  84.133  -9.078  1.00 44.35  ? 313 GLN D O   1 
ATOM   13144 C CB  . GLN D 1 313 ? -5.311  81.788  -6.986  1.00 55.99  ? 313 GLN D CB  1 
ATOM   13145 C CG  . GLN D 1 313 ? -6.519  81.155  -6.307  1.00 64.15  ? 313 GLN D CG  1 
ATOM   13146 C CD  . GLN D 1 313 ? -6.155  80.439  -5.031  1.00 69.22  ? 313 GLN D CD  1 
ATOM   13147 O OE1 . GLN D 1 313 ? -6.132  79.205  -4.994  1.00 64.04  ? 313 GLN D OE1 1 
ATOM   13148 N NE2 . GLN D 1 313 ? -5.838  81.208  -3.997  1.00 76.75  ? 313 GLN D NE2 1 
ATOM   13149 N N   . VAL D 1 314 ? -3.006  83.673  -7.676  1.00 43.23  ? 314 VAL D N   1 
ATOM   13150 C CA  . VAL D 1 314 ? -1.946  83.737  -8.667  1.00 41.20  ? 314 VAL D CA  1 
ATOM   13151 C C   . VAL D 1 314 ? -1.853  82.391  -9.377  1.00 40.08  ? 314 VAL D C   1 
ATOM   13152 O O   . VAL D 1 314 ? -2.084  81.347  -8.761  1.00 40.71  ? 314 VAL D O   1 
ATOM   13153 C CB  . VAL D 1 314 ? -0.599  84.080  -8.007  1.00 43.20  ? 314 VAL D CB  1 
ATOM   13154 C CG1 . VAL D 1 314 ? -0.546  85.541  -7.567  1.00 40.90  ? 314 VAL D CG1 1 
ATOM   13155 C CG2 . VAL D 1 314 ? -0.255  83.105  -6.872  1.00 42.00  ? 314 VAL D CG2 1 
ATOM   13156 N N   . ILE D 1 315 ? -1.479  82.437  -10.659 1.00 37.89  ? 315 ILE D N   1 
ATOM   13157 C CA  . ILE D 1 315 ? -0.989  81.267  -11.374 1.00 35.99  ? 315 ILE D CA  1 
ATOM   13158 C C   . ILE D 1 315 ? 0.468   81.066  -10.968 1.00 36.91  ? 315 ILE D C   1 
ATOM   13159 O O   . ILE D 1 315 ? 1.329   81.912  -11.245 1.00 31.85  ? 315 ILE D O   1 
ATOM   13160 C CB  . ILE D 1 315 ? -1.166  81.443  -12.892 1.00 38.48  ? 315 ILE D CB  1 
ATOM   13161 C CG1 . ILE D 1 315 ? -2.637  81.726  -13.223 1.00 38.09  ? 315 ILE D CG1 1 
ATOM   13162 C CG2 . ILE D 1 315 ? -0.619  80.237  -13.666 1.00 38.93  ? 315 ILE D CG2 1 
ATOM   13163 C CD1 . ILE D 1 315 ? -2.863  82.250  -14.619 1.00 42.05  ? 315 ILE D CD1 1 
ATOM   13164 N N   . PRO D 1 316 ? 0.777   79.951  -10.268 1.00 38.53  ? 316 PRO D N   1 
ATOM   13165 C CA  . PRO D 1 316 ? 2.101   79.774  -9.681  1.00 40.36  ? 316 PRO D CA  1 
ATOM   13166 C C   . PRO D 1 316 ? 3.140   79.482  -10.763 1.00 39.88  ? 316 PRO D C   1 
ATOM   13167 O O   . PRO D 1 316 ? 2.817   78.903  -11.811 1.00 37.98  ? 316 PRO D O   1 
ATOM   13168 C CB  . PRO D 1 316 ? 1.931   78.612  -8.696  1.00 41.92  ? 316 PRO D CB  1 
ATOM   13169 C CG  . PRO D 1 316 ? 0.604   77.969  -9.037  1.00 42.56  ? 316 PRO D CG  1 
ATOM   13170 C CD  . PRO D 1 316 ? -0.078  78.763  -10.129 1.00 39.46  ? 316 PRO D CD  1 
ATOM   13171 N N   . GLY D 1 317 ? 4.385   79.899  -10.493 1.00 37.63  ? 317 GLY D N   1 
ATOM   13172 C CA  . GLY D 1 317 ? 5.508   79.624  -11.383 1.00 37.61  ? 317 GLY D CA  1 
ATOM   13173 C C   . GLY D 1 317 ? 5.638   80.631  -12.526 1.00 36.13  ? 317 GLY D C   1 
ATOM   13174 O O   . GLY D 1 317 ? 6.479   80.467  -13.410 1.00 36.14  ? 317 GLY D O   1 
ATOM   13175 N N   . TYR D 1 318 ? 4.788   81.661  -12.517 1.00 33.00  ? 318 TYR D N   1 
ATOM   13176 C CA  . TYR D 1 318 ? 4.814   82.671  -13.553 1.00 34.15  ? 318 TYR D CA  1 
ATOM   13177 C C   . TYR D 1 318 ? 5.004   84.024  -12.875 1.00 36.05  ? 318 TYR D C   1 
ATOM   13178 O O   . TYR D 1 318 ? 4.587   84.232  -11.736 1.00 38.18  ? 318 TYR D O   1 
ATOM   13179 C CB  . TYR D 1 318 ? 3.552   82.537  -14.428 1.00 35.38  ? 318 TYR D CB  1 
ATOM   13180 C CG  . TYR D 1 318 ? 3.664   81.410  -15.441 1.00 32.39  ? 318 TYR D CG  1 
ATOM   13181 C CD1 . TYR D 1 318 ? 3.524   80.094  -15.044 1.00 32.19  ? 318 TYR D CD1 1 
ATOM   13182 C CD2 . TYR D 1 318 ? 4.000   81.650  -16.764 1.00 33.93  ? 318 TYR D CD2 1 
ATOM   13183 C CE1 . TYR D 1 318 ? 3.657   79.049  -15.936 1.00 33.09  ? 318 TYR D CE1 1 
ATOM   13184 C CE2 . TYR D 1 318 ? 4.141   80.610  -17.673 1.00 35.64  ? 318 TYR D CE2 1 
ATOM   13185 C CZ  . TYR D 1 318 ? 3.966   79.301  -17.260 1.00 34.89  ? 318 TYR D CZ  1 
ATOM   13186 O OH  . TYR D 1 318 ? 4.132   78.234  -18.102 1.00 31.75  ? 318 TYR D OH  1 
ATOM   13187 N N   . GLY D 1 319 ? 5.669   84.934  -13.581 1.00 39.39  ? 319 GLY D N   1 
ATOM   13188 C CA  . GLY D 1 319 ? 5.877   86.272  -13.066 1.00 41.34  ? 319 GLY D CA  1 
ATOM   13189 C C   . GLY D 1 319 ? 7.161   86.333  -12.253 1.00 41.48  ? 319 GLY D C   1 
ATOM   13190 O O   . GLY D 1 319 ? 7.660   85.302  -11.802 1.00 43.34  ? 319 GLY D O   1 
ATOM   13191 N N   . HIS D 1 320 ? 7.678   87.554  -12.079 1.00 39.47  ? 320 HIS D N   1 
ATOM   13192 C CA  . HIS D 1 320 ? 8.860   87.774  -11.271 1.00 38.20  ? 320 HIS D CA  1 
ATOM   13193 C C   . HIS D 1 320 ? 8.980   89.247  -10.895 1.00 39.69  ? 320 HIS D C   1 
ATOM   13194 O O   . HIS D 1 320 ? 8.523   90.100  -11.647 1.00 39.94  ? 320 HIS D O   1 
ATOM   13195 C CB  . HIS D 1 320 ? 10.103  87.329  -12.043 1.00 40.75  ? 320 HIS D CB  1 
ATOM   13196 C CG  . HIS D 1 320 ? 11.268  87.046  -11.162 1.00 42.68  ? 320 HIS D CG  1 
ATOM   13197 N ND1 . HIS D 1 320 ? 12.291  87.942  -10.951 1.00 35.65  ? 320 HIS D ND1 1 
ATOM   13198 C CD2 . HIS D 1 320 ? 11.561  85.935  -10.444 1.00 43.72  ? 320 HIS D CD2 1 
ATOM   13199 C CE1 . HIS D 1 320 ? 13.174  87.378  -10.141 1.00 42.98  ? 320 HIS D CE1 1 
ATOM   13200 N NE2 . HIS D 1 320 ? 12.747  86.160  -9.820  1.00 45.17  ? 320 HIS D NE2 1 
ATOM   13201 N N   . ALA D 1 321 ? 9.664   89.517  -9.768  1.00 44.58  ? 321 ALA D N   1 
ATOM   13202 C CA  . ALA D 1 321 ? 9.958   90.867  -9.306  1.00 46.02  ? 321 ALA D CA  1 
ATOM   13203 C C   . ALA D 1 321 ? 10.649  91.708  -10.382 1.00 51.61  ? 321 ALA D C   1 
ATOM   13204 O O   . ALA D 1 321 ? 10.310  92.879  -10.563 1.00 53.48  ? 321 ALA D O   1 
ATOM   13205 C CB  . ALA D 1 321 ? 10.792  90.820  -8.036  1.00 43.17  ? 321 ALA D CB  1 
ATOM   13206 N N   . VAL D 1 322 ? 11.641  91.140  -11.078 1.00 51.97  ? 322 VAL D N   1 
ATOM   13207 C CA  . VAL D 1 322 ? 12.492  91.959  -11.931 1.00 49.90  ? 322 VAL D CA  1 
ATOM   13208 C C   . VAL D 1 322 ? 12.567  91.380  -13.338 1.00 51.30  ? 322 VAL D C   1 
ATOM   13209 O O   . VAL D 1 322 ? 12.718  92.144  -14.291 1.00 60.31  ? 322 VAL D O   1 
ATOM   13210 C CB  . VAL D 1 322 ? 13.898  92.154  -11.341 1.00 49.21  ? 322 VAL D CB  1 
ATOM   13211 C CG1 . VAL D 1 322 ? 13.841  92.912  -10.026 1.00 53.09  ? 322 VAL D CG1 1 
ATOM   13212 C CG2 . VAL D 1 322 ? 14.637  90.835  -11.168 1.00 50.64  ? 322 VAL D CG2 1 
ATOM   13213 N N   . LEU D 1 323 ? 12.511  90.045  -13.460 1.00 50.65  ? 323 LEU D N   1 
ATOM   13214 C CA  . LEU D 1 323 ? 12.594  89.387  -14.758 1.00 45.11  ? 323 LEU D CA  1 
ATOM   13215 C C   . LEU D 1 323 ? 11.402  89.851  -15.591 1.00 42.09  ? 323 LEU D C   1 
ATOM   13216 O O   . LEU D 1 323 ? 10.338  90.133  -15.051 1.00 44.43  ? 323 LEU D O   1 
ATOM   13217 C CB  . LEU D 1 323 ? 12.656  87.853  -14.673 1.00 41.03  ? 323 LEU D CB  1 
ATOM   13218 C CG  . LEU D 1 323 ? 13.943  87.212  -14.126 1.00 37.61  ? 323 LEU D CG  1 
ATOM   13219 C CD1 . LEU D 1 323 ? 13.859  85.688  -14.101 1.00 37.35  ? 323 LEU D CD1 1 
ATOM   13220 C CD2 . LEU D 1 323 ? 15.189  87.623  -14.879 1.00 38.61  ? 323 LEU D CD2 1 
ATOM   13221 N N   . ARG D 1 324 ? 11.604  89.957  -16.901 1.00 39.20  ? 324 ARG D N   1 
ATOM   13222 C CA  . ARG D 1 324 ? 10.535  90.350  -17.802 1.00 47.36  ? 324 ARG D CA  1 
ATOM   13223 C C   . ARG D 1 324 ? 10.546  89.474  -19.054 1.00 52.86  ? 324 ARG D C   1 
ATOM   13224 O O   . ARG D 1 324 ? 9.844   89.779  -20.020 1.00 50.13  ? 324 ARG D O   1 
ATOM   13225 C CB  . ARG D 1 324 ? 10.722  91.818  -18.206 1.00 47.85  ? 324 ARG D CB  1 
ATOM   13226 C CG  . ARG D 1 324 ? 10.669  92.827  -17.067 1.00 45.57  ? 324 ARG D CG  1 
ATOM   13227 C CD  . ARG D 1 324 ? 9.255   93.120  -16.643 1.00 46.13  ? 324 ARG D CD  1 
ATOM   13228 N NE  . ARG D 1 324 ? 9.181   93.975  -15.454 1.00 46.39  ? 324 ARG D NE  1 
ATOM   13229 C CZ  . ARG D 1 324 ? 8.890   93.524  -14.246 1.00 49.64  ? 324 ARG D CZ  1 
ATOM   13230 N NH1 . ARG D 1 324 ? 8.987   92.226  -13.976 1.00 49.24  ? 324 ARG D NH1 1 
ATOM   13231 N NH2 . ARG D 1 324 ? 8.554   94.386  -13.300 1.00 54.02  ? 324 ARG D NH2 1 
ATOM   13232 N N   . VAL D 1 325 ? 11.357  88.402  -19.026 1.00 52.38  ? 325 VAL D N   1 
ATOM   13233 C CA  . VAL D 1 325 ? 11.429  87.430  -20.105 1.00 49.71  ? 325 VAL D CA  1 
ATOM   13234 C C   . VAL D 1 325 ? 11.447  86.037  -19.482 1.00 45.50  ? 325 VAL D C   1 
ATOM   13235 O O   . VAL D 1 325 ? 11.562  85.881  -18.266 1.00 46.43  ? 325 VAL D O   1 
ATOM   13236 C CB  . VAL D 1 325 ? 12.656  87.664  -21.012 1.00 55.89  ? 325 VAL D CB  1 
ATOM   13237 C CG1 . VAL D 1 325 ? 12.598  89.015  -21.724 1.00 59.23  ? 325 VAL D CG1 1 
ATOM   13238 C CG2 . VAL D 1 325 ? 13.977  87.538  -20.257 1.00 54.85  ? 325 VAL D CG2 1 
ATOM   13239 N N   . THR D 1 326 ? 11.334  85.014  -20.323 1.00 41.70  ? 326 THR D N   1 
ATOM   13240 C CA  . THR D 1 326 ? 11.426  83.661  -19.819 1.00 41.83  ? 326 THR D CA  1 
ATOM   13241 C C   . THR D 1 326 ? 12.723  83.547  -19.011 1.00 42.07  ? 326 THR D C   1 
ATOM   13242 O O   . THR D 1 326 ? 13.787  84.011  -19.434 1.00 35.44  ? 326 THR D O   1 
ATOM   13243 C CB  . THR D 1 326 ? 11.358  82.651  -20.964 1.00 44.71  ? 326 THR D CB  1 
ATOM   13244 O OG1 . THR D 1 326 ? 10.169  82.891  -21.718 1.00 50.38  ? 326 THR D OG1 1 
ATOM   13245 C CG2 . THR D 1 326 ? 11.310  81.226  -20.441 1.00 44.86  ? 326 THR D CG2 1 
ATOM   13246 N N   . ASP D 1 327 ? 12.613  82.942  -17.820 1.00 39.05  ? 327 ASP D N   1 
ATOM   13247 C CA  . ASP D 1 327 ? 13.746  82.774  -16.930 1.00 33.95  ? 327 ASP D CA  1 
ATOM   13248 C C   . ASP D 1 327 ? 14.679  81.723  -17.529 1.00 30.85  ? 327 ASP D C   1 
ATOM   13249 O O   . ASP D 1 327 ? 14.263  80.613  -17.880 1.00 29.83  ? 327 ASP D O   1 
ATOM   13250 C CB  . ASP D 1 327 ? 13.238  82.535  -15.519 1.00 35.48  ? 327 ASP D CB  1 
ATOM   13251 C CG  . ASP D 1 327 ? 14.231  82.291  -14.385 1.00 35.28  ? 327 ASP D CG  1 
ATOM   13252 O OD1 . ASP D 1 327 ? 15.476  82.311  -14.602 1.00 34.04  ? 327 ASP D OD1 1 
ATOM   13253 O OD2 . ASP D 1 327 ? 13.729  82.050  -13.273 1.00 31.62  ? 327 ASP D OD2 1 
ATOM   13254 N N   . PRO D 1 328 ? 15.977  82.059  -17.715 1.00 29.55  ? 328 PRO D N   1 
ATOM   13255 C CA  . PRO D 1 328 ? 16.918  81.102  -18.297 1.00 29.38  ? 328 PRO D CA  1 
ATOM   13256 C C   . PRO D 1 328 ? 17.036  79.866  -17.407 1.00 29.20  ? 328 PRO D C   1 
ATOM   13257 O O   . PRO D 1 328 ? 17.364  78.788  -17.895 1.00 29.03  ? 328 PRO D O   1 
ATOM   13258 C CB  . PRO D 1 328 ? 18.258  81.873  -18.472 1.00 30.46  ? 328 PRO D CB  1 
ATOM   13259 C CG  . PRO D 1 328 ? 18.082  83.184  -17.703 1.00 29.45  ? 328 PRO D CG  1 
ATOM   13260 C CD  . PRO D 1 328 ? 16.582  83.378  -17.448 1.00 27.57  ? 328 PRO D CD  1 
ATOM   13261 N N   . ARG D 1 329 ? 16.734  80.030  -16.113 1.00 26.61  ? 329 ARG D N   1 
ATOM   13262 C CA  . ARG D 1 329 ? 16.755  78.923  -15.182 1.00 27.98  ? 329 ARG D CA  1 
ATOM   13263 C C   . ARG D 1 329 ? 15.635  77.940  -15.524 1.00 32.82  ? 329 ARG D C   1 
ATOM   13264 O O   . ARG D 1 329 ? 15.759  76.740  -15.250 1.00 31.77  ? 329 ARG D O   1 
ATOM   13265 C CB  . ARG D 1 329 ? 16.652  79.439  -13.743 1.00 28.34  ? 329 ARG D CB  1 
ATOM   13266 C CG  . ARG D 1 329 ? 17.828  80.306  -13.302 1.00 28.20  ? 329 ARG D CG  1 
ATOM   13267 C CD  . ARG D 1 329 ? 17.647  80.870  -11.903 1.00 27.57  ? 329 ARG D CD  1 
ATOM   13268 N NE  . ARG D 1 329 ? 16.401  81.637  -11.753 1.00 28.00  ? 329 ARG D NE  1 
ATOM   13269 C CZ  . ARG D 1 329 ? 15.918  82.138  -10.622 1.00 28.31  ? 329 ARG D CZ  1 
ATOM   13270 N NH1 . ARG D 1 329 ? 16.564  81.930  -9.499  1.00 31.10  ? 329 ARG D NH1 1 
ATOM   13271 N NH2 . ARG D 1 329 ? 14.813  82.875  -10.599 1.00 29.23  ? 329 ARG D NH2 1 
ATOM   13272 N N   . TYR D 1 330 ? 14.543  78.455  -16.109 1.00 33.11  ? 330 TYR D N   1 
ATOM   13273 C CA  . TYR D 1 330 ? 13.437  77.615  -16.538 1.00 33.08  ? 330 TYR D CA  1 
ATOM   13274 C C   . TYR D 1 330 ? 13.849  76.830  -17.773 1.00 29.65  ? 330 TYR D C   1 
ATOM   13275 O O   . TYR D 1 330 ? 13.617  75.621  -17.849 1.00 30.89  ? 330 TYR D O   1 
ATOM   13276 C CB  . TYR D 1 330 ? 12.185  78.426  -16.893 1.00 33.99  ? 330 TYR D CB  1 
ATOM   13277 C CG  . TYR D 1 330 ? 10.982  77.667  -17.458 1.00 30.33  ? 330 TYR D CG  1 
ATOM   13278 C CD1 . TYR D 1 330 ? 10.004  77.142  -16.616 1.00 27.88  ? 330 TYR D CD1 1 
ATOM   13279 C CD2 . TYR D 1 330 ? 10.773  77.561  -18.832 1.00 29.22  ? 330 TYR D CD2 1 
ATOM   13280 C CE1 . TYR D 1 330 ? 8.880   76.506  -17.113 1.00 27.67  ? 330 TYR D CE1 1 
ATOM   13281 C CE2 . TYR D 1 330 ? 9.641   76.942  -19.343 1.00 29.41  ? 330 TYR D CE2 1 
ATOM   13282 C CZ  . TYR D 1 330 ? 8.696   76.416  -18.479 1.00 29.09  ? 330 TYR D CZ  1 
ATOM   13283 O OH  . TYR D 1 330 ? 7.599   75.775  -18.953 1.00 32.92  ? 330 TYR D OH  1 
ATOM   13284 N N   . VAL D 1 331 ? 14.429  77.558  -18.725 1.00 26.60  ? 331 VAL D N   1 
ATOM   13285 C CA  . VAL D 1 331 ? 14.784  77.013  -20.028 1.00 27.53  ? 331 VAL D CA  1 
ATOM   13286 C C   . VAL D 1 331 ? 15.743  75.841  -19.849 1.00 29.06  ? 331 VAL D C   1 
ATOM   13287 O O   . VAL D 1 331 ? 15.607  74.808  -20.517 1.00 30.63  ? 331 VAL D O   1 
ATOM   13288 C CB  . VAL D 1 331 ? 15.423  78.064  -20.954 1.00 27.72  ? 331 VAL D CB  1 
ATOM   13289 C CG1 . VAL D 1 331 ? 15.874  77.430  -22.258 1.00 29.72  ? 331 VAL D CG1 1 
ATOM   13290 C CG2 . VAL D 1 331 ? 14.506  79.254  -21.209 1.00 26.75  ? 331 VAL D CG2 1 
ATOM   13291 N N   . ALA D 1 332 ? 16.724  76.012  -18.956 1.00 27.46  ? 332 ALA D N   1 
ATOM   13292 C CA  . ALA D 1 332 ? 17.682  74.949  -18.692 1.00 28.09  ? 332 ALA D CA  1 
ATOM   13293 C C   . ALA D 1 332 ? 17.006  73.668  -18.195 1.00 25.78  ? 332 ALA D C   1 
ATOM   13294 O O   . ALA D 1 332 ? 17.424  72.580  -18.541 1.00 24.87  ? 332 ALA D O   1 
ATOM   13295 C CB  . ALA D 1 332 ? 18.721  75.445  -17.710 1.00 29.87  ? 332 ALA D CB  1 
ATOM   13296 N N   . GLN D 1 333 ? 15.955  73.782  -17.383 1.00 27.48  ? 333 GLN D N   1 
ATOM   13297 C CA  . GLN D 1 333 ? 15.252  72.602  -16.895 1.00 29.62  ? 333 GLN D CA  1 
ATOM   13298 C C   . GLN D 1 333 ? 14.327  72.007  -17.961 1.00 28.77  ? 333 GLN D C   1 
ATOM   13299 O O   . GLN D 1 333 ? 14.113  70.789  -18.008 1.00 28.45  ? 333 GLN D O   1 
ATOM   13300 C CB  . GLN D 1 333 ? 14.449  72.936  -15.642 1.00 29.29  ? 333 GLN D CB  1 
ATOM   13301 C CG  . GLN D 1 333 ? 15.303  73.421  -14.484 1.00 29.70  ? 333 GLN D CG  1 
ATOM   13302 C CD  . GLN D 1 333 ? 14.433  73.806  -13.321 1.00 31.87  ? 333 GLN D CD  1 
ATOM   13303 O OE1 . GLN D 1 333 ? 13.992  72.937  -12.559 1.00 30.07  ? 333 GLN D OE1 1 
ATOM   13304 N NE2 . GLN D 1 333 ? 14.123  75.095  -13.231 1.00 32.69  ? 333 GLN D NE2 1 
ATOM   13305 N N   . ARG D 1 334 ? 13.792  72.874  -18.818 1.00 28.27  ? 334 ARG D N   1 
ATOM   13306 C CA  . ARG D 1 334 ? 13.089  72.422  -20.005 1.00 31.06  ? 334 ARG D CA  1 
ATOM   13307 C C   . ARG D 1 334 ? 14.015  71.542  -20.853 1.00 27.91  ? 334 ARG D C   1 
ATOM   13308 O O   . ARG D 1 334 ? 13.589  70.454  -21.250 1.00 29.95  ? 334 ARG D O   1 
ATOM   13309 C CB  . ARG D 1 334 ? 12.486  73.618  -20.760 1.00 33.85  ? 334 ARG D CB  1 
ATOM   13310 C CG  . ARG D 1 334 ? 11.730  73.261  -22.031 1.00 36.53  ? 334 ARG D CG  1 
ATOM   13311 C CD  . ARG D 1 334 ? 11.015  74.473  -22.683 1.00 40.84  ? 334 ARG D CD  1 
ATOM   13312 N NE  . ARG D 1 334 ? 10.316  74.131  -23.933 1.00 40.55  ? 334 ARG D NE  1 
ATOM   13313 C CZ  . ARG D 1 334 ? 9.297   73.251  -24.086 1.00 44.42  ? 334 ARG D CZ  1 
ATOM   13314 N NH1 . ARG D 1 334 ? 8.596   72.781  -23.066 1.00 45.61  ? 334 ARG D NH1 1 
ATOM   13315 N NH2 . ARG D 1 334 ? 8.945   72.851  -25.293 1.00 46.12  ? 334 ARG D NH2 1 
ATOM   13316 N N   . ASP D 1 335 ? 15.260  71.984  -21.112 1.00 24.13  ? 335 ASP D N   1 
ATOM   13317 C CA  . ASP D 1 335 ? 16.191  71.191  -21.907 1.00 28.99  ? 335 ASP D CA  1 
ATOM   13318 C C   . ASP D 1 335 ? 16.443  69.833  -21.248 1.00 29.78  ? 335 ASP D C   1 
ATOM   13319 O O   . ASP D 1 335 ? 16.478  68.794  -21.926 1.00 29.66  ? 335 ASP D O   1 
ATOM   13320 C CB  . ASP D 1 335 ? 17.538  71.851  -22.163 1.00 34.95  ? 335 ASP D CB  1 
ATOM   13321 C CG  . ASP D 1 335 ? 17.538  73.230  -22.819 1.00 44.45  ? 335 ASP D CG  1 
ATOM   13322 O OD1 . ASP D 1 335 ? 16.485  73.628  -23.395 1.00 58.61  ? 335 ASP D OD1 1 
ATOM   13323 O OD2 . ASP D 1 335 ? 18.593  73.913  -22.730 1.00 44.99  ? 335 ASP D OD2 1 
ATOM   13324 N N   . PHE D 1 336 ? 16.615  69.838  -19.920 1.00 28.26  ? 336 PHE D N   1 
ATOM   13325 C CA  . PHE D 1 336 ? 16.790  68.598  -19.184 1.00 27.19  ? 336 PHE D CA  1 
ATOM   13326 C C   . PHE D 1 336 ? 15.599  67.655  -19.387 1.00 28.95  ? 336 PHE D C   1 
ATOM   13327 O O   . PHE D 1 336 ? 15.768  66.448  -19.590 1.00 27.89  ? 336 PHE D O   1 
ATOM   13328 C CB  . PHE D 1 336 ? 16.953  68.916  -17.698 1.00 26.95  ? 336 PHE D CB  1 
ATOM   13329 C CG  . PHE D 1 336 ? 17.315  67.660  -16.929 1.00 25.21  ? 336 PHE D CG  1 
ATOM   13330 C CD1 . PHE D 1 336 ? 16.322  66.794  -16.474 1.00 24.13  ? 336 PHE D CD1 1 
ATOM   13331 C CD2 . PHE D 1 336 ? 18.642  67.314  -16.725 1.00 24.78  ? 336 PHE D CD2 1 
ATOM   13332 C CE1 . PHE D 1 336 ? 16.650  65.631  -15.805 1.00 24.38  ? 336 PHE D CE1 1 
ATOM   13333 C CE2 . PHE D 1 336 ? 18.963  66.152  -16.031 1.00 25.49  ? 336 PHE D CE2 1 
ATOM   13334 C CZ  . PHE D 1 336 ? 17.969  65.311  -15.590 1.00 25.08  ? 336 PHE D CZ  1 
ATOM   13335 N N   . ALA D 1 337 ? 14.386  68.200  -19.295 1.00 27.56  ? 337 ALA D N   1 
ATOM   13336 C CA  . ALA D 1 337 ? 13.205  67.365  -19.365 1.00 30.22  ? 337 ALA D CA  1 
ATOM   13337 C C   . ALA D 1 337 ? 12.985  66.828  -20.787 1.00 32.69  ? 337 ALA D C   1 
ATOM   13338 O O   . ALA D 1 337 ? 12.721  65.638  -20.954 1.00 29.03  ? 337 ALA D O   1 
ATOM   13339 C CB  . ALA D 1 337 ? 12.031  68.165  -18.862 1.00 30.23  ? 337 ALA D CB  1 
ATOM   13340 N N   . LEU D 1 338 ? 13.092  67.702  -21.803 1.00 32.99  ? 338 LEU D N   1 
ATOM   13341 C CA  . LEU D 1 338 ? 13.035  67.292  -23.212 1.00 38.05  ? 338 LEU D CA  1 
ATOM   13342 C C   . LEU D 1 338 ? 13.969  66.115  -23.479 1.00 37.51  ? 338 LEU D C   1 
ATOM   13343 O O   . LEU D 1 338 ? 13.602  65.184  -24.199 1.00 39.83  ? 338 LEU D O   1 
ATOM   13344 C CB  . LEU D 1 338 ? 13.357  68.422  -24.203 1.00 33.42  ? 338 LEU D CB  1 
ATOM   13345 C CG  . LEU D 1 338 ? 12.320  69.548  -24.256 1.00 33.27  ? 338 LEU D CG  1 
ATOM   13346 C CD1 . LEU D 1 338 ? 12.774  70.789  -24.967 1.00 32.10  ? 338 LEU D CD1 1 
ATOM   13347 C CD2 . LEU D 1 338 ? 11.051  69.018  -24.863 1.00 35.65  ? 338 LEU D CD2 1 
ATOM   13348 N N   . LYS D 1 339 ? 15.180  66.200  -22.918 1.00 39.44  ? 339 LYS D N   1 
ATOM   13349 C CA  . LYS D 1 339 ? 16.188  65.176  -23.096 1.00 39.34  ? 339 LYS D CA  1 
ATOM   13350 C C   . LYS D 1 339 ? 15.768  63.916  -22.327 1.00 36.49  ? 339 LYS D C   1 
ATOM   13351 O O   . LYS D 1 339 ? 15.673  62.848  -22.925 1.00 42.04  ? 339 LYS D O   1 
ATOM   13352 C CB  . LYS D 1 339 ? 17.533  65.828  -22.757 1.00 46.98  ? 339 LYS D CB  1 
ATOM   13353 C CG  . LYS D 1 339 ? 18.724  65.563  -23.690 1.00 60.26  ? 339 LYS D CG  1 
ATOM   13354 C CD  . LYS D 1 339 ? 19.664  64.403  -23.357 1.00 73.11  ? 339 LYS D CD  1 
ATOM   13355 C CE  . LYS D 1 339 ? 19.243  63.071  -23.911 1.00 79.58  ? 339 LYS D CE  1 
ATOM   13356 N NZ  . LYS D 1 339 ? 19.294  63.035  -25.376 1.00 80.84  ? 339 LYS D NZ  1 
ATOM   13357 N N   . HIS D 1 340 ? 15.435  64.011  -21.034 1.00 32.70  ? 340 HIS D N   1 
ATOM   13358 C CA  . HIS D 1 340 ? 15.394  62.810  -20.203 1.00 32.65  ? 340 HIS D CA  1 
ATOM   13359 C C   . HIS D 1 340 ? 13.994  62.259  -19.882 1.00 33.42  ? 340 HIS D C   1 
ATOM   13360 O O   . HIS D 1 340 ? 13.921  61.108  -19.457 1.00 35.77  ? 340 HIS D O   1 
ATOM   13361 C CB  . HIS D 1 340 ? 16.183  63.021  -18.906 1.00 34.67  ? 340 HIS D CB  1 
ATOM   13362 C CG  . HIS D 1 340 ? 17.572  63.502  -19.126 1.00 33.70  ? 340 HIS D CG  1 
ATOM   13363 N ND1 . HIS D 1 340 ? 18.566  62.642  -19.542 1.00 36.05  ? 340 HIS D ND1 1 
ATOM   13364 C CD2 . HIS D 1 340 ? 18.125  64.734  -19.049 1.00 30.98  ? 340 HIS D CD2 1 
ATOM   13365 C CE1 . HIS D 1 340 ? 19.695  63.338  -19.692 1.00 36.03  ? 340 HIS D CE1 1 
ATOM   13366 N NE2 . HIS D 1 340 ? 19.452  64.613  -19.391 1.00 31.77  ? 340 HIS D NE2 1 
ATOM   13367 N N   . LEU D 1 341 ? 12.891  63.026  -20.043 1.00 35.13  ? 341 LEU D N   1 
ATOM   13368 C CA  . LEU D 1 341 ? 11.556  62.535  -19.697 1.00 32.03  ? 341 LEU D CA  1 
ATOM   13369 C C   . LEU D 1 341 ? 10.471  63.234  -20.515 1.00 32.91  ? 341 LEU D C   1 
ATOM   13370 O O   . LEU D 1 341 ? 9.556   63.827  -19.959 1.00 33.24  ? 341 LEU D O   1 
ATOM   13371 C CB  . LEU D 1 341 ? 11.306  62.742  -18.201 1.00 35.32  ? 341 LEU D CB  1 
ATOM   13372 C CG  . LEU D 1 341 ? 11.494  64.168  -17.653 1.00 33.92  ? 341 LEU D CG  1 
ATOM   13373 C CD1 . LEU D 1 341 ? 10.313  64.588  -16.838 1.00 33.07  ? 341 LEU D CD1 1 
ATOM   13374 C CD2 . LEU D 1 341 ? 12.725  64.327  -16.788 1.00 34.71  ? 341 LEU D CD2 1 
ATOM   13375 N N   . PRO D 1 342 ? 10.501  63.213  -21.865 1.00 36.91  ? 342 PRO D N   1 
ATOM   13376 C CA  . PRO D 1 342 ? 9.570   64.033  -22.647 1.00 34.86  ? 342 PRO D CA  1 
ATOM   13377 C C   . PRO D 1 342 ? 8.145   63.498  -22.728 1.00 37.40  ? 342 PRO D C   1 
ATOM   13378 O O   . PRO D 1 342 ? 7.244   64.237  -23.094 1.00 40.32  ? 342 PRO D O   1 
ATOM   13379 C CB  . PRO D 1 342 ? 10.263  64.101  -24.005 1.00 38.19  ? 342 PRO D CB  1 
ATOM   13380 C CG  . PRO D 1 342 ? 10.983  62.761  -24.124 1.00 39.33  ? 342 PRO D CG  1 
ATOM   13381 C CD  . PRO D 1 342 ? 11.456  62.465  -22.703 1.00 41.08  ? 342 PRO D CD  1 
ATOM   13382 N N   . ASP D 1 343 ? 7.943   62.243  -22.309 1.00 41.36  ? 343 ASP D N   1 
ATOM   13383 C CA  . ASP D 1 343 ? 6.643   61.591  -22.364 1.00 41.59  ? 343 ASP D CA  1 
ATOM   13384 C C   . ASP D 1 343 ? 5.933   61.621  -21.003 1.00 43.50  ? 343 ASP D C   1 
ATOM   13385 O O   . ASP D 1 343 ? 4.785   61.172  -20.916 1.00 41.85  ? 343 ASP D O   1 
ATOM   13386 C CB  . ASP D 1 343 ? 6.783   60.162  -22.877 1.00 45.68  ? 343 ASP D CB  1 
ATOM   13387 C CG  . ASP D 1 343 ? 7.461   59.979  -24.238 1.00 52.82  ? 343 ASP D CG  1 
ATOM   13388 O OD1 . ASP D 1 343 ? 7.138   60.739  -25.193 1.00 51.43  ? 343 ASP D OD1 1 
ATOM   13389 O OD2 . ASP D 1 343 ? 8.322   59.071  -24.345 1.00 52.05  ? 343 ASP D OD2 1 
ATOM   13390 N N   . ASP D 1 344 ? 6.619   62.131  -19.953 1.00 42.85  ? 344 ASP D N   1 
ATOM   13391 C CA  . ASP D 1 344 ? 6.083   62.314  -18.604 1.00 34.21  ? 344 ASP D CA  1 
ATOM   13392 C C   . ASP D 1 344 ? 4.927   63.313  -18.637 1.00 34.95  ? 344 ASP D C   1 
ATOM   13393 O O   . ASP D 1 344 ? 5.067   64.441  -19.132 1.00 31.20  ? 344 ASP D O   1 
ATOM   13394 C CB  . ASP D 1 344 ? 7.146   62.875  -17.668 1.00 33.23  ? 344 ASP D CB  1 
ATOM   13395 C CG  . ASP D 1 344 ? 6.782   63.027  -16.194 1.00 32.73  ? 344 ASP D CG  1 
ATOM   13396 O OD1 . ASP D 1 344 ? 6.096   64.020  -15.850 1.00 30.43  ? 344 ASP D OD1 1 
ATOM   13397 O OD2 . ASP D 1 344 ? 7.193   62.153  -15.398 1.00 27.48  ? 344 ASP D OD2 1 
ATOM   13398 N N   . GLU D 1 345 ? 3.789   62.907  -18.072 1.00 34.58  ? 345 GLU D N   1 
ATOM   13399 C CA  . GLU D 1 345 ? 2.543   63.632  -18.285 1.00 37.55  ? 345 GLU D CA  1 
ATOM   13400 C C   . GLU D 1 345 ? 2.503   64.968  -17.528 1.00 34.45  ? 345 GLU D C   1 
ATOM   13401 O O   . GLU D 1 345 ? 2.029   65.966  -18.067 1.00 34.75  ? 345 GLU D O   1 
ATOM   13402 C CB  . GLU D 1 345 ? 1.380   62.687  -17.998 1.00 42.81  ? 345 GLU D CB  1 
ATOM   13403 C CG  . GLU D 1 345 ? 1.278   61.543  -19.005 1.00 46.62  ? 345 GLU D CG  1 
ATOM   13404 C CD  . GLU D 1 345 ? -0.144  61.029  -19.090 1.00 52.38  ? 345 GLU D CD  1 
ATOM   13405 O OE1 . GLU D 1 345 ? -0.740  61.176  -20.171 1.00 64.42  ? 345 GLU D OE1 1 
ATOM   13406 O OE2 . GLU D 1 345 ? -0.667  60.529  -18.079 1.00 49.74  ? 345 GLU D OE2 1 
ATOM   13407 N N   . LEU D 1 346 ? 3.020   65.004  -16.292 1.00 31.04  ? 346 LEU D N   1 
ATOM   13408 C CA  . LEU D 1 346 ? 3.133   66.243  -15.548 1.00 28.87  ? 346 LEU D CA  1 
ATOM   13409 C C   . LEU D 1 346 ? 4.022   67.185  -16.352 1.00 28.91  ? 346 LEU D C   1 
ATOM   13410 O O   . LEU D 1 346 ? 3.740   68.366  -16.479 1.00 26.62  ? 346 LEU D O   1 
ATOM   13411 C CB  . LEU D 1 346 ? 3.640   65.981  -14.121 1.00 29.43  ? 346 LEU D CB  1 
ATOM   13412 C CG  . LEU D 1 346 ? 2.723   65.121  -13.243 1.00 33.32  ? 346 LEU D CG  1 
ATOM   13413 C CD1 . LEU D 1 346 ? 3.092   65.037  -11.771 1.00 34.07  ? 346 LEU D CD1 1 
ATOM   13414 C CD2 . LEU D 1 346 ? 1.283   65.623  -13.314 1.00 35.90  ? 346 LEU D CD2 1 
ATOM   13415 N N   . PHE D 1 347 ? 5.107   66.655  -16.924 1.00 34.41  ? 347 PHE D N   1 
ATOM   13416 C CA  . PHE D 1 347 ? 5.993   67.498  -17.705 1.00 34.47  ? 347 PHE D CA  1 
ATOM   13417 C C   . PHE D 1 347 ? 5.203   68.072  -18.881 1.00 34.17  ? 347 PHE D C   1 
ATOM   13418 O O   . PHE D 1 347 ? 5.305   69.262  -19.188 1.00 32.26  ? 347 PHE D O   1 
ATOM   13419 C CB  . PHE D 1 347 ? 7.268   66.760  -18.139 1.00 30.86  ? 347 PHE D CB  1 
ATOM   13420 C CG  . PHE D 1 347 ? 8.019   67.563  -19.184 1.00 26.19  ? 347 PHE D CG  1 
ATOM   13421 C CD1 . PHE D 1 347 ? 8.268   68.905  -18.987 1.00 24.56  ? 347 PHE D CD1 1 
ATOM   13422 C CD2 . PHE D 1 347 ? 8.360   67.000  -20.404 1.00 29.10  ? 347 PHE D CD2 1 
ATOM   13423 C CE1 . PHE D 1 347 ? 8.886   69.659  -19.966 1.00 27.07  ? 347 PHE D CE1 1 
ATOM   13424 C CE2 . PHE D 1 347 ? 8.994   67.753  -21.377 1.00 28.17  ? 347 PHE D CE2 1 
ATOM   13425 C CZ  . PHE D 1 347 ? 9.226   69.088  -21.168 1.00 27.19  ? 347 PHE D CZ  1 
ATOM   13426 N N   . LYS D 1 348 ? 4.392   67.207  -19.504 1.00 38.19  ? 348 LYS D N   1 
ATOM   13427 C CA  . LYS D 1 348 ? 3.583   67.586  -20.657 1.00 40.07  ? 348 LYS D CA  1 
ATOM   13428 C C   . LYS D 1 348 ? 2.702   68.779  -20.308 1.00 32.87  ? 348 LYS D C   1 
ATOM   13429 O O   . LYS D 1 348 ? 2.549   69.669  -21.136 1.00 33.20  ? 348 LYS D O   1 
ATOM   13430 C CB  . LYS D 1 348 ? 2.776   66.408  -21.220 1.00 45.19  ? 348 LYS D CB  1 
ATOM   13431 C CG  . LYS D 1 348 ? 3.469   65.513  -22.286 1.00 53.67  ? 348 LYS D CG  1 
ATOM   13432 C CD  . LYS D 1 348 ? 2.867   64.100  -22.350 1.00 63.07  ? 348 LYS D CD  1 
ATOM   13433 C CE  . LYS D 1 348 ? 3.136   63.248  -23.575 1.00 70.27  ? 348 LYS D CE  1 
ATOM   13434 N NZ  . LYS D 1 348 ? 2.526   63.769  -24.808 1.00 67.89  ? 348 LYS D NZ  1 
ATOM   13435 N N   . ILE D 1 349 ? 2.149   68.794  -19.090 1.00 30.22  ? 349 ILE D N   1 
ATOM   13436 C CA  . ILE D 1 349 ? 1.313   69.902  -18.635 1.00 32.82  ? 349 ILE D CA  1 
ATOM   13437 C C   . ILE D 1 349 ? 2.146   71.172  -18.462 1.00 32.90  ? 349 ILE D C   1 
ATOM   13438 O O   . ILE D 1 349 ? 1.662   72.268  -18.746 1.00 35.72  ? 349 ILE D O   1 
ATOM   13439 C CB  . ILE D 1 349 ? 0.568   69.538  -17.340 1.00 35.34  ? 349 ILE D CB  1 
ATOM   13440 C CG1 . ILE D 1 349 ? -0.315  68.306  -17.550 1.00 38.40  ? 349 ILE D CG1 1 
ATOM   13441 C CG2 . ILE D 1 349 ? -0.230  70.729  -16.808 1.00 35.33  ? 349 ILE D CG2 1 
ATOM   13442 C CD1 . ILE D 1 349 ? -1.097  67.875  -16.324 1.00 41.28  ? 349 ILE D CD1 1 
ATOM   13443 N N   . VAL D 1 350 ? 3.380   71.016  -17.968 1.00 32.02  ? 350 VAL D N   1 
ATOM   13444 C CA  . VAL D 1 350 ? 4.257   72.138  -17.715 1.00 32.36  ? 350 VAL D CA  1 
ATOM   13445 C C   . VAL D 1 350 ? 4.591   72.761  -19.061 1.00 35.88  ? 350 VAL D C   1 
ATOM   13446 O O   . VAL D 1 350 ? 4.572   73.982  -19.182 1.00 35.06  ? 350 VAL D O   1 
ATOM   13447 C CB  . VAL D 1 350 ? 5.534   71.717  -16.959 1.00 35.18  ? 350 VAL D CB  1 
ATOM   13448 C CG1 . VAL D 1 350 ? 6.677   72.714  -17.155 1.00 34.74  ? 350 VAL D CG1 1 
ATOM   13449 C CG2 . VAL D 1 350 ? 5.289   71.452  -15.470 1.00 36.04  ? 350 VAL D CG2 1 
ATOM   13450 N N   . SER D 1 351 ? 4.938   71.900  -20.040 1.00 35.42  ? 351 SER D N   1 
ATOM   13451 C CA  . SER D 1 351 ? 5.258   72.311  -21.405 1.00 33.86  ? 351 SER D CA  1 
ATOM   13452 C C   . SER D 1 351 ? 4.068   73.007  -22.076 1.00 36.69  ? 351 SER D C   1 
ATOM   13453 O O   . SER D 1 351 ? 4.215   74.067  -22.686 1.00 39.51  ? 351 SER D O   1 
ATOM   13454 C CB  . SER D 1 351 ? 5.691   71.121  -22.227 1.00 32.91  ? 351 SER D CB  1 
ATOM   13455 O OG  . SER D 1 351 ? 6.189   71.562  -23.477 1.00 32.70  ? 351 SER D OG  1 
ATOM   13456 N N   . LEU D 1 352 ? 2.871   72.426  -21.933 1.00 38.17  ? 352 LEU D N   1 
ATOM   13457 C CA  . LEU D 1 352 ? 1.668   73.035  -22.483 1.00 40.85  ? 352 LEU D CA  1 
ATOM   13458 C C   . LEU D 1 352 ? 1.428   74.412  -21.876 1.00 34.69  ? 352 LEU D C   1 
ATOM   13459 O O   . LEU D 1 352 ? 1.103   75.331  -22.617 1.00 34.46  ? 352 LEU D O   1 
ATOM   13460 C CB  . LEU D 1 352 ? 0.449   72.136  -22.316 1.00 45.50  ? 352 LEU D CB  1 
ATOM   13461 C CG  . LEU D 1 352 ? -0.750  72.494  -23.199 1.00 46.82  ? 352 LEU D CG  1 
ATOM   13462 C CD1 . LEU D 1 352 ? -0.456  72.184  -24.659 1.00 46.54  ? 352 LEU D CD1 1 
ATOM   13463 C CD2 . LEU D 1 352 ? -1.990  71.747  -22.720 1.00 44.25  ? 352 LEU D CD2 1 
ATOM   13464 N N   . CYS D 1 353 ? 1.641   74.561  -20.562 1.00 31.57  ? 353 CYS D N   1 
ATOM   13465 C CA  . CYS D 1 353 ? 1.498   75.860  -19.909 1.00 34.88  ? 353 CYS D CA  1 
ATOM   13466 C C   . CYS D 1 353 ? 2.397   76.927  -20.536 1.00 33.74  ? 353 CYS D C   1 
ATOM   13467 O O   . CYS D 1 353 ? 2.051   78.108  -20.496 1.00 34.29  ? 353 CYS D O   1 
ATOM   13468 C CB  . CYS D 1 353 ? 1.798   75.823  -18.405 1.00 37.35  ? 353 CYS D CB  1 
ATOM   13469 S SG  . CYS D 1 353 ? 0.532   74.979  -17.414 1.00 32.10  ? 353 CYS D SG  1 
ATOM   13470 N N   . TYR D 1 354 ? 3.551   76.529  -21.090 1.00 35.26  ? 354 TYR D N   1 
ATOM   13471 C CA  . TYR D 1 354 ? 4.521   77.478  -21.630 1.00 39.83  ? 354 TYR D CA  1 
ATOM   13472 C C   . TYR D 1 354 ? 3.937   78.152  -22.878 1.00 41.22  ? 354 TYR D C   1 
ATOM   13473 O O   . TYR D 1 354 ? 4.214   79.330  -23.144 1.00 37.82  ? 354 TYR D O   1 
ATOM   13474 C CB  . TYR D 1 354 ? 5.848   76.720  -21.842 1.00 45.57  ? 354 TYR D CB  1 
ATOM   13475 C CG  . TYR D 1 354 ? 7.053   77.537  -22.310 1.00 43.35  ? 354 TYR D CG  1 
ATOM   13476 C CD1 . TYR D 1 354 ? 7.216   78.867  -21.938 1.00 44.53  ? 354 TYR D CD1 1 
ATOM   13477 C CD2 . TYR D 1 354 ? 8.024   76.980  -23.138 1.00 41.75  ? 354 TYR D CD2 1 
ATOM   13478 C CE1 . TYR D 1 354 ? 8.285   79.625  -22.396 1.00 48.91  ? 354 TYR D CE1 1 
ATOM   13479 C CE2 . TYR D 1 354 ? 9.099   77.727  -23.597 1.00 43.45  ? 354 TYR D CE2 1 
ATOM   13480 C CZ  . TYR D 1 354 ? 9.233   79.059  -23.230 1.00 47.83  ? 354 TYR D CZ  1 
ATOM   13481 O OH  . TYR D 1 354 ? 10.280  79.843  -23.669 1.00 46.77  ? 354 TYR D OH  1 
ATOM   13482 N N   . GLU D 1 355 ? 3.103   77.393  -23.610 1.00 44.27  ? 355 GLU D N   1 
ATOM   13483 C CA  . GLU D 1 355 ? 2.434   77.873  -24.811 1.00 48.36  ? 355 GLU D CA  1 
ATOM   13484 C C   . GLU D 1 355 ? 1.180   78.673  -24.454 1.00 45.25  ? 355 GLU D C   1 
ATOM   13485 O O   . GLU D 1 355 ? 0.856   79.607  -25.168 1.00 43.38  ? 355 GLU D O   1 
ATOM   13486 C CB  . GLU D 1 355 ? 1.970   76.777  -25.776 1.00 49.86  ? 355 GLU D CB  1 
ATOM   13487 C CG  . GLU D 1 355 ? 3.014   75.711  -26.096 1.00 53.34  ? 355 GLU D CG  1 
ATOM   13488 C CD  . GLU D 1 355 ? 2.589   74.617  -27.081 1.00 57.94  ? 355 GLU D CD  1 
ATOM   13489 O OE1 . GLU D 1 355 ? 3.223   73.548  -27.032 1.00 53.51  ? 355 GLU D OE1 1 
ATOM   13490 O OE2 . GLU D 1 355 ? 1.688   74.803  -27.935 1.00 59.44  ? 355 GLU D OE2 1 
ATOM   13491 N N   . VAL D 1 356 ? 0.474   78.322  -23.367 1.00 42.52  ? 356 VAL D N   1 
ATOM   13492 C CA  . VAL D 1 356 ? -0.865  78.852  -23.127 1.00 37.65  ? 356 VAL D CA  1 
ATOM   13493 C C   . VAL D 1 356 ? -0.909  79.961  -22.073 1.00 37.48  ? 356 VAL D C   1 
ATOM   13494 O O   . VAL D 1 356 ? -1.563  80.970  -22.301 1.00 41.46  ? 356 VAL D O   1 
ATOM   13495 C CB  . VAL D 1 356 ? -1.756  77.657  -22.780 1.00 37.02  ? 356 VAL D CB  1 
ATOM   13496 C CG1 . VAL D 1 356 ? -3.172  78.064  -22.374 1.00 38.10  ? 356 VAL D CG1 1 
ATOM   13497 C CG2 . VAL D 1 356 ? -1.785  76.679  -23.955 1.00 39.15  ? 356 VAL D CG2 1 
ATOM   13498 N N   . ILE D 1 357 ? -0.221  79.798  -20.935 1.00 38.00  ? 357 ILE D N   1 
ATOM   13499 C CA  . ILE D 1 357 ? -0.409  80.652  -19.767 1.00 35.82  ? 357 ILE D CA  1 
ATOM   13500 C C   . ILE D 1 357 ? 0.031   82.089  -20.049 1.00 40.61  ? 357 ILE D C   1 
ATOM   13501 O O   . ILE D 1 357 ? -0.553  83.041  -19.516 1.00 37.75  ? 357 ILE D O   1 
ATOM   13502 C CB  . ILE D 1 357 ? 0.360   80.100  -18.554 1.00 35.31  ? 357 ILE D CB  1 
ATOM   13503 C CG1 . ILE D 1 357 ? -0.099  78.701  -18.174 1.00 35.43  ? 357 ILE D CG1 1 
ATOM   13504 C CG2 . ILE D 1 357 ? 0.281   81.067  -17.370 1.00 36.02  ? 357 ILE D CG2 1 
ATOM   13505 C CD1 . ILE D 1 357 ? -1.568  78.629  -17.809 1.00 39.24  ? 357 ILE D CD1 1 
ATOM   13506 N N   . PRO D 1 358 ? 1.153   82.314  -20.768 1.00 41.55  ? 358 PRO D N   1 
ATOM   13507 C CA  . PRO D 1 358 ? 1.581   83.691  -21.036 1.00 41.69  ? 358 PRO D CA  1 
ATOM   13508 C C   . PRO D 1 358 ? 0.542   84.546  -21.772 1.00 46.37  ? 358 PRO D C   1 
ATOM   13509 O O   . PRO D 1 358 ? 0.418   85.748  -21.507 1.00 41.34  ? 358 PRO D O   1 
ATOM   13510 C CB  . PRO D 1 358 ? 2.916   83.534  -21.793 1.00 39.90  ? 358 PRO D CB  1 
ATOM   13511 C CG  . PRO D 1 358 ? 3.400   82.132  -21.421 1.00 41.68  ? 358 PRO D CG  1 
ATOM   13512 C CD  . PRO D 1 358 ? 2.143   81.296  -21.177 1.00 40.97  ? 358 PRO D CD  1 
ATOM   13513 N N   . GLU D 1 359 ? -0.221  83.923  -22.680 1.00 52.75  ? 359 GLU D N   1 
ATOM   13514 C CA  . GLU D 1 359 ? -1.311  84.602  -23.366 1.00 53.42  ? 359 GLU D CA  1 
ATOM   13515 C C   . GLU D 1 359 ? -2.365  85.013  -22.334 1.00 50.25  ? 359 GLU D C   1 
ATOM   13516 O O   . GLU D 1 359 ? -2.784  86.168  -22.273 1.00 51.09  ? 359 GLU D O   1 
ATOM   13517 C CB  . GLU D 1 359 ? -1.923  83.708  -24.448 1.00 60.72  ? 359 GLU D CB  1 
ATOM   13518 C CG  . GLU D 1 359 ? -2.564  84.495  -25.589 1.00 67.09  ? 359 GLU D CG  1 
ATOM   13519 C CD  . GLU D 1 359 ? -1.540  85.319  -26.356 1.00 70.61  ? 359 GLU D CD  1 
ATOM   13520 O OE1 . GLU D 1 359 ? -0.653  84.714  -27.004 1.00 69.42  ? 359 GLU D OE1 1 
ATOM   13521 O OE2 . GLU D 1 359 ? -1.609  86.564  -26.275 1.00 64.63  ? 359 GLU D OE2 1 
ATOM   13522 N N   . VAL D 1 360 ? -2.780  84.060  -21.498 1.00 46.14  ? 360 VAL D N   1 
ATOM   13523 C CA  . VAL D 1 360 ? -3.770  84.327  -20.465 1.00 46.26  ? 360 VAL D CA  1 
ATOM   13524 C C   . VAL D 1 360 ? -3.349  85.529  -19.621 1.00 47.99  ? 360 VAL D C   1 
ATOM   13525 O O   . VAL D 1 360 ? -4.179  86.395  -19.348 1.00 48.90  ? 360 VAL D O   1 
ATOM   13526 C CB  . VAL D 1 360 ? -4.029  83.115  -19.554 1.00 46.70  ? 360 VAL D CB  1 
ATOM   13527 C CG1 . VAL D 1 360 ? -4.813  83.510  -18.311 1.00 47.13  ? 360 VAL D CG1 1 
ATOM   13528 C CG2 . VAL D 1 360 ? -4.722  81.974  -20.289 1.00 51.55  ? 360 VAL D CG2 1 
ATOM   13529 N N   . LEU D 1 361 ? -2.080  85.546  -19.180 1.00 49.09  ? 361 LEU D N   1 
ATOM   13530 C CA  . LEU D 1 361 ? -1.596  86.521  -18.210 1.00 48.88  ? 361 LEU D CA  1 
ATOM   13531 C C   . LEU D 1 361 ? -1.415  87.892  -18.864 1.00 47.99  ? 361 LEU D C   1 
ATOM   13532 O O   . LEU D 1 361 ? -1.495  88.911  -18.176 1.00 49.64  ? 361 LEU D O   1 
ATOM   13533 C CB  . LEU D 1 361 ? -0.299  86.066  -17.536 1.00 46.98  ? 361 LEU D CB  1 
ATOM   13534 C CG  . LEU D 1 361 ? -0.430  85.055  -16.388 1.00 48.30  ? 361 LEU D CG  1 
ATOM   13535 C CD1 . LEU D 1 361 ? 0.940   84.490  -16.078 1.00 52.93  ? 361 LEU D CD1 1 
ATOM   13536 C CD2 . LEU D 1 361 ? -1.026  85.638  -15.119 1.00 45.49  ? 361 LEU D CD2 1 
ATOM   13537 N N   . LYS D 1 362 ? -1.128  87.899  -20.172 1.00 46.48  ? 362 LYS D N   1 
ATOM   13538 C CA  . LYS D 1 362 ? -1.002  89.125  -20.946 1.00 50.84  ? 362 LYS D CA  1 
ATOM   13539 C C   . LYS D 1 362 ? -2.355  89.830  -21.070 1.00 51.00  ? 362 LYS D C   1 
ATOM   13540 O O   . LYS D 1 362 ? -2.416  91.050  -20.944 1.00 47.13  ? 362 LYS D O   1 
ATOM   13541 C CB  . LYS D 1 362 ? -0.457  88.827  -22.349 1.00 51.73  ? 362 LYS D CB  1 
ATOM   13542 C CG  . LYS D 1 362 ? 1.051   88.780  -22.486 1.00 53.68  ? 362 LYS D CG  1 
ATOM   13543 C CD  . LYS D 1 362 ? 1.449   88.140  -23.810 1.00 61.69  ? 362 LYS D CD  1 
ATOM   13544 C CE  . LYS D 1 362 ? 2.912   88.210  -24.140 1.00 61.38  ? 362 LYS D CE  1 
ATOM   13545 N NZ  . LYS D 1 362 ? 3.213   87.557  -25.416 1.00 57.93  ? 362 LYS D NZ  1 
ATOM   13546 N N   . LYS D 1 363 ? -3.416  89.051  -21.342 1.00 53.89  ? 363 LYS D N   1 
ATOM   13547 C CA  . LYS D 1 363 ? -4.770  89.564  -21.493 1.00 54.53  ? 363 LYS D CA  1 
ATOM   13548 C C   . LYS D 1 363 ? -5.304  90.015  -20.138 1.00 47.74  ? 363 LYS D C   1 
ATOM   13549 O O   . LYS D 1 363 ? -5.777  91.140  -19.999 1.00 45.83  ? 363 LYS D O   1 
ATOM   13550 C CB  . LYS D 1 363 ? -5.671  88.492  -22.114 1.00 54.56  ? 363 LYS D CB  1 
ATOM   13551 C CG  . LYS D 1 363 ? -5.546  88.403  -23.618 1.00 62.39  ? 363 LYS D CG  1 
ATOM   13552 C CD  . LYS D 1 363 ? -5.892  87.012  -24.145 1.00 75.39  ? 363 LYS D CD  1 
ATOM   13553 C CE  . LYS D 1 363 ? -6.005  86.948  -25.631 1.00 81.35  ? 363 LYS D CE  1 
ATOM   13554 N NZ  . LYS D 1 363 ? -5.033  87.815  -26.308 1.00 88.33  ? 363 LYS D NZ  1 
ATOM   13555 N N   . HIS D 1 364 ? -5.201  89.127  -19.147 1.00 47.34  ? 364 HIS D N   1 
ATOM   13556 C CA  . HIS D 1 364 ? -5.467  89.469  -17.758 1.00 50.04  ? 364 HIS D CA  1 
ATOM   13557 C C   . HIS D 1 364 ? -4.886  90.850  -17.469 1.00 49.13  ? 364 HIS D C   1 
ATOM   13558 O O   . HIS D 1 364 ? -5.553  91.689  -16.876 1.00 55.01  ? 364 HIS D O   1 
ATOM   13559 C CB  . HIS D 1 364 ? -4.945  88.357  -16.845 1.00 54.07  ? 364 HIS D CB  1 
ATOM   13560 C CG  . HIS D 1 364 ? -5.219  88.549  -15.396 1.00 56.38  ? 364 HIS D CG  1 
ATOM   13561 N ND1 . HIS D 1 364 ? -4.251  88.903  -14.480 1.00 56.40  ? 364 HIS D ND1 1 
ATOM   13562 C CD2 . HIS D 1 364 ? -6.353  88.373  -14.705 1.00 57.65  ? 364 HIS D CD2 1 
ATOM   13563 C CE1 . HIS D 1 364 ? -4.802  88.956  -13.277 1.00 61.99  ? 364 HIS D CE1 1 
ATOM   13564 N NE2 . HIS D 1 364 ? -6.083  88.645  -13.393 1.00 59.23  ? 364 HIS D NE2 1 
ATOM   13565 N N   . GLY D 1 365 ? -3.652  91.085  -17.928 1.00 49.29  ? 365 GLY D N   1 
ATOM   13566 C CA  . GLY D 1 365 ? -3.093  92.425  -18.016 1.00 48.19  ? 365 GLY D CA  1 
ATOM   13567 C C   . GLY D 1 365 ? -2.630  92.981  -16.668 1.00 52.43  ? 365 GLY D C   1 
ATOM   13568 O O   . GLY D 1 365 ? -2.442  94.185  -16.561 1.00 49.79  ? 365 GLY D O   1 
ATOM   13569 N N   . LYS D 1 366 ? -2.407  92.114  -15.669 1.00 57.33  ? 366 LYS D N   1 
ATOM   13570 C CA  . LYS D 1 366 ? -1.926  92.543  -14.361 1.00 67.24  ? 366 LYS D CA  1 
ATOM   13571 C C   . LYS D 1 366 ? -0.417  92.322  -14.229 1.00 66.19  ? 366 LYS D C   1 
ATOM   13572 O O   . LYS D 1 366 ? 0.336   93.245  -13.898 1.00 57.68  ? 366 LYS D O   1 
ATOM   13573 C CB  . LYS D 1 366 ? -2.633  91.758  -13.249 1.00 77.73  ? 366 LYS D CB  1 
ATOM   13574 C CG  . LYS D 1 366 ? -4.098  92.110  -13.021 1.00 85.02  ? 366 LYS D CG  1 
ATOM   13575 C CD  . LYS D 1 366 ? -4.319  93.498  -12.433 1.00 89.51  ? 366 LYS D CD  1 
ATOM   13576 C CE  . LYS D 1 366 ? -5.686  94.026  -12.711 1.00 91.11  ? 366 LYS D CE  1 
ATOM   13577 N NZ  . LYS D 1 366 ? -5.809  95.393  -12.212 1.00 90.96  ? 366 LYS D NZ  1 
ATOM   13578 N N   . ALA D 1 367 ? 0.006   91.074  -14.472 1.00 63.79  ? 367 ALA D N   1 
ATOM   13579 C CA  . ALA D 1 367 ? 1.392   90.661  -14.293 1.00 59.04  ? 367 ALA D CA  1 
ATOM   13580 C C   . ALA D 1 367 ? 2.322   91.415  -15.245 1.00 52.25  ? 367 ALA D C   1 
ATOM   13581 O O   . ALA D 1 367 ? 2.041   91.445  -16.437 1.00 49.35  ? 367 ALA D O   1 
ATOM   13582 C CB  . ALA D 1 367 ? 1.490   89.167  -14.514 1.00 57.59  ? 367 ALA D CB  1 
ATOM   13583 N N   . LYS D 1 368 ? 3.424   91.989  -14.717 1.00 52.10  ? 368 LYS D N   1 
ATOM   13584 C CA  . LYS D 1 368 ? 4.418   92.705  -15.518 1.00 53.75  ? 368 LYS D CA  1 
ATOM   13585 C C   . LYS D 1 368 ? 5.298   91.709  -16.277 1.00 46.41  ? 368 LYS D C   1 
ATOM   13586 O O   . LYS D 1 368 ? 5.848   92.032  -17.321 1.00 45.80  ? 368 LYS D O   1 
ATOM   13587 C CB  . LYS D 1 368 ? 5.240   93.714  -14.700 1.00 59.42  ? 368 LYS D CB  1 
ATOM   13588 C CG  . LYS D 1 368 ? 4.432   94.945  -14.242 1.00 70.59  ? 368 LYS D CG  1 
ATOM   13589 C CD  . LYS D 1 368 ? 5.190   96.257  -14.050 1.00 76.28  ? 368 LYS D CD  1 
ATOM   13590 C CE  . LYS D 1 368 ? 5.720   96.466  -12.661 1.00 79.68  ? 368 LYS D CE  1 
ATOM   13591 N NZ  . LYS D 1 368 ? 6.671   97.583  -12.599 1.00 77.91  ? 368 LYS D NZ  1 
ATOM   13592 N N   . ASN D 1 369 ? 5.399   90.485  -15.761 1.00 42.75  ? 369 ASN D N   1 
ATOM   13593 C CA  . ASN D 1 369 ? 6.098   89.412  -16.437 1.00 38.63  ? 369 ASN D CA  1 
ATOM   13594 C C   . ASN D 1 369 ? 5.092   88.282  -16.638 1.00 37.08  ? 369 ASN D C   1 
ATOM   13595 O O   . ASN D 1 369 ? 4.662   87.665  -15.672 1.00 34.36  ? 369 ASN D O   1 
ATOM   13596 C CB  . ASN D 1 369 ? 7.316   88.999  -15.617 1.00 41.42  ? 369 ASN D CB  1 
ATOM   13597 C CG  . ASN D 1 369 ? 8.094   87.821  -16.174 1.00 45.28  ? 369 ASN D CG  1 
ATOM   13598 O OD1 . ASN D 1 369 ? 7.964   87.460  -17.348 1.00 44.59  ? 369 ASN D OD1 1 
ATOM   13599 N ND2 . ASN D 1 369 ? 8.930   87.203  -15.350 1.00 47.03  ? 369 ASN D ND2 1 
ATOM   13600 N N   . PRO D 1 370 ? 4.684   87.970  -17.886 1.00 38.77  ? 370 PRO D N   1 
ATOM   13601 C CA  . PRO D 1 370 ? 3.788   86.836  -18.135 1.00 37.97  ? 370 PRO D CA  1 
ATOM   13602 C C   . PRO D 1 370 ? 4.462   85.477  -18.348 1.00 39.75  ? 370 PRO D C   1 
ATOM   13603 O O   . PRO D 1 370 ? 3.776   84.483  -18.615 1.00 40.01  ? 370 PRO D O   1 
ATOM   13604 C CB  . PRO D 1 370 ? 3.083   87.331  -19.416 1.00 37.91  ? 370 PRO D CB  1 
ATOM   13605 C CG  . PRO D 1 370 ? 4.177   88.067  -20.179 1.00 39.32  ? 370 PRO D CG  1 
ATOM   13606 C CD  . PRO D 1 370 ? 5.075   88.684  -19.119 1.00 39.26  ? 370 PRO D CD  1 
ATOM   13607 N N   . TRP D 1 371 ? 5.804   85.438  -18.244 1.00 40.11  ? 371 TRP D N   1 
ATOM   13608 C CA  . TRP D 1 371 ? 6.602   84.269  -18.611 1.00 40.24  ? 371 TRP D CA  1 
ATOM   13609 C C   . TRP D 1 371 ? 6.960   83.428  -17.379 1.00 36.64  ? 371 TRP D C   1 
ATOM   13610 O O   . TRP D 1 371 ? 6.939   83.930  -16.249 1.00 34.66  ? 371 TRP D O   1 
ATOM   13611 C CB  . TRP D 1 371 ? 7.878   84.695  -19.360 1.00 41.08  ? 371 TRP D CB  1 
ATOM   13612 C CG  . TRP D 1 371 ? 7.579   85.515  -20.576 1.00 43.94  ? 371 TRP D CG  1 
ATOM   13613 C CD1 . TRP D 1 371 ? 7.642   86.870  -20.695 1.00 45.40  ? 371 TRP D CD1 1 
ATOM   13614 C CD2 . TRP D 1 371 ? 7.073   85.019  -21.827 1.00 49.57  ? 371 TRP D CD2 1 
ATOM   13615 N NE1 . TRP D 1 371 ? 7.239   87.249  -21.943 1.00 47.38  ? 371 TRP D NE1 1 
ATOM   13616 C CE2 . TRP D 1 371 ? 6.880   86.142  -22.662 1.00 49.52  ? 371 TRP D CE2 1 
ATOM   13617 C CE3 . TRP D 1 371 ? 6.782   83.743  -22.325 1.00 56.78  ? 371 TRP D CE3 1 
ATOM   13618 C CZ2 . TRP D 1 371 ? 6.407   86.028  -23.969 1.00 52.59  ? 371 TRP D CZ2 1 
ATOM   13619 C CZ3 . TRP D 1 371 ? 6.317   83.629  -23.620 1.00 60.74  ? 371 TRP D CZ3 1 
ATOM   13620 C CH2 . TRP D 1 371 ? 6.121   84.757  -24.424 1.00 55.95  ? 371 TRP D CH2 1 
ATOM   13621 N N   . PRO D 1 372 ? 7.337   82.136  -17.575 1.00 33.36  ? 372 PRO D N   1 
ATOM   13622 C CA  . PRO D 1 372 ? 7.670   81.242  -16.465 1.00 31.99  ? 372 PRO D CA  1 
ATOM   13623 C C   . PRO D 1 372 ? 8.954   81.671  -15.764 1.00 29.28  ? 372 PRO D C   1 
ATOM   13624 O O   . PRO D 1 372 ? 9.861   82.201  -16.394 1.00 28.92  ? 372 PRO D O   1 
ATOM   13625 C CB  . PRO D 1 372 ? 7.802   79.813  -17.080 1.00 31.18  ? 372 PRO D CB  1 
ATOM   13626 C CG  . PRO D 1 372 ? 7.601   79.977  -18.573 1.00 29.52  ? 372 PRO D CG  1 
ATOM   13627 C CD  . PRO D 1 372 ? 7.469   81.460  -18.876 1.00 30.56  ? 372 PRO D CD  1 
ATOM   13628 N N   . ASN D 1 373 ? 8.998   81.438  -14.452 1.00 27.97  ? 373 ASN D N   1 
ATOM   13629 C CA  . ASN D 1 373 ? 10.242  81.453  -13.694 1.00 30.07  ? 373 ASN D CA  1 
ATOM   13630 C C   . ASN D 1 373 ? 10.636  80.013  -13.299 1.00 28.86  ? 373 ASN D C   1 
ATOM   13631 O O   . ASN D 1 373 ? 9.894   79.057  -13.541 1.00 26.80  ? 373 ASN D O   1 
ATOM   13632 C CB  . ASN D 1 373 ? 10.112  82.371  -12.484 1.00 28.55  ? 373 ASN D CB  1 
ATOM   13633 C CG  . ASN D 1 373 ? 9.015   81.871  -11.581 1.00 29.94  ? 373 ASN D CG  1 
ATOM   13634 O OD1 . ASN D 1 373 ? 9.126   80.768  -11.034 1.00 27.45  ? 373 ASN D OD1 1 
ATOM   13635 N ND2 . ASN D 1 373 ? 7.935   82.631  -11.459 1.00 33.17  ? 373 ASN D ND2 1 
ATOM   13636 N N   . VAL D 1 374 ? 11.781  79.896  -12.612 1.00 25.30  ? 374 VAL D N   1 
ATOM   13637 C CA  . VAL D 1 374 ? 12.426  78.631  -12.284 1.00 27.04  ? 374 VAL D CA  1 
ATOM   13638 C C   . VAL D 1 374 ? 11.476  77.656  -11.585 1.00 26.11  ? 374 VAL D C   1 
ATOM   13639 O O   . VAL D 1 374 ? 11.508  76.435  -11.813 1.00 26.53  ? 374 VAL D O   1 
ATOM   13640 C CB  . VAL D 1 374 ? 13.680  78.935  -11.426 1.00 27.92  ? 374 VAL D CB  1 
ATOM   13641 C CG1 . VAL D 1 374 ? 13.372  79.665  -10.112 1.00 26.80  ? 374 VAL D CG1 1 
ATOM   13642 C CG2 . VAL D 1 374 ? 14.506  77.678  -11.171 1.00 27.16  ? 374 VAL D CG2 1 
ATOM   13643 N N   . ASP D 1 375 ? 10.648  78.212  -10.710 1.00 26.71  ? 375 ASP D N   1 
ATOM   13644 C CA  . ASP D 1 375 ? 9.803   77.433  -9.832  1.00 28.71  ? 375 ASP D CA  1 
ATOM   13645 C C   . ASP D 1 375 ? 8.727   76.713  -10.658 1.00 27.89  ? 375 ASP D C   1 
ATOM   13646 O O   . ASP D 1 375 ? 8.136   75.728  -10.182 1.00 24.41  ? 375 ASP D O   1 
ATOM   13647 C CB  . ASP D 1 375 ? 9.292   78.324  -8.705  1.00 32.53  ? 375 ASP D CB  1 
ATOM   13648 C CG  . ASP D 1 375 ? 10.355  78.898  -7.774  1.00 34.03  ? 375 ASP D CG  1 
ATOM   13649 O OD1 . ASP D 1 375 ? 11.281  78.133  -7.404  1.00 35.26  ? 375 ASP D OD1 1 
ATOM   13650 O OD2 . ASP D 1 375 ? 10.231  80.097  -7.395  1.00 32.86  ? 375 ASP D OD2 1 
ATOM   13651 N N   . ALA D 1 376 ? 8.513   77.160  -11.914 1.00 24.95  ? 376 ALA D N   1 
ATOM   13652 C CA  . ALA D 1 376 ? 7.514   76.527  -12.762 1.00 23.54  ? 376 ALA D CA  1 
ATOM   13653 C C   . ALA D 1 376 ? 7.921   75.110  -13.179 1.00 25.77  ? 376 ALA D C   1 
ATOM   13654 O O   . ALA D 1 376 ? 7.051   74.315  -13.537 1.00 21.46  ? 376 ALA D O   1 
ATOM   13655 C CB  . ALA D 1 376 ? 7.239   77.374  -13.960 1.00 22.81  ? 376 ALA D CB  1 
ATOM   13656 N N   . HIS D 1 377 ? 9.232   74.791  -13.135 1.00 28.18  ? 377 HIS D N   1 
ATOM   13657 C CA  . HIS D 1 377 ? 9.733   73.593  -13.802 1.00 28.06  ? 377 HIS D CA  1 
ATOM   13658 C C   . HIS D 1 377 ? 10.341  72.533  -12.873 1.00 29.46  ? 377 HIS D C   1 
ATOM   13659 O O   . HIS D 1 377 ? 10.487  71.378  -13.299 1.00 27.73  ? 377 HIS D O   1 
ATOM   13660 C CB  . HIS D 1 377 ? 10.746  73.984  -14.873 1.00 24.76  ? 377 HIS D CB  1 
ATOM   13661 C CG  . HIS D 1 377 ? 10.611  73.154  -16.102 1.00 25.39  ? 377 HIS D CG  1 
ATOM   13662 N ND1 . HIS D 1 377 ? 10.543  71.774  -16.055 1.00 25.36  ? 377 HIS D ND1 1 
ATOM   13663 C CD2 . HIS D 1 377 ? 10.544  73.512  -17.408 1.00 24.60  ? 377 HIS D CD2 1 
ATOM   13664 C CE1 . HIS D 1 377 ? 10.423  71.314  -17.301 1.00 26.68  ? 377 HIS D CE1 1 
ATOM   13665 N NE2 . HIS D 1 377 ? 10.433  72.346  -18.136 1.00 28.24  ? 377 HIS D NE2 1 
ATOM   13666 N N   . SER D 1 378 ? 10.692  72.918  -11.630 1.00 29.65  ? 378 SER D N   1 
ATOM   13667 C CA  . SER D 1 378 ? 11.562  72.105  -10.780 1.00 30.13  ? 378 SER D CA  1 
ATOM   13668 C C   . SER D 1 378 ? 10.815  70.919  -10.176 1.00 27.07  ? 378 SER D C   1 
ATOM   13669 O O   . SER D 1 378 ? 11.355  69.816  -10.144 1.00 28.10  ? 378 SER D O   1 
ATOM   13670 C CB  . SER D 1 378 ? 12.264  72.929  -9.715  1.00 28.66  ? 378 SER D CB  1 
ATOM   13671 O OG  . SER D 1 378 ? 11.405  73.907  -9.133  1.00 30.25  ? 378 SER D OG  1 
ATOM   13672 N N   . GLY D 1 379 ? 9.566   71.143  -9.768  1.00 25.01  ? 379 GLY D N   1 
ATOM   13673 C CA  . GLY D 1 379 ? 8.779   70.161  -9.036  1.00 26.96  ? 379 GLY D CA  1 
ATOM   13674 C C   . GLY D 1 379 ? 8.526   68.888  -9.837  1.00 29.33  ? 379 GLY D C   1 
ATOM   13675 O O   . GLY D 1 379 ? 8.527   67.778  -9.285  1.00 25.70  ? 379 GLY D O   1 
ATOM   13676 N N   . VAL D 1 380 ? 8.272   69.055  -11.143 1.00 33.53  ? 380 VAL D N   1 
ATOM   13677 C CA  . VAL D 1 380 ? 7.843   67.921  -11.953 1.00 34.73  ? 380 VAL D CA  1 
ATOM   13678 C C   . VAL D 1 380 ? 9.056   67.040  -12.226 1.00 32.09  ? 380 VAL D C   1 
ATOM   13679 O O   . VAL D 1 380 ? 8.890   65.838  -12.434 1.00 31.70  ? 380 VAL D O   1 
ATOM   13680 C CB  . VAL D 1 380 ? 7.132   68.282  -13.267 1.00 35.57  ? 380 VAL D CB  1 
ATOM   13681 C CG1 . VAL D 1 380 ? 5.736   68.833  -13.006 1.00 37.73  ? 380 VAL D CG1 1 
ATOM   13682 C CG2 . VAL D 1 380 ? 7.964   69.238  -14.115 1.00 36.93  ? 380 VAL D CG2 1 
ATOM   13683 N N   . LEU D 1 381 ? 10.248  67.658  -12.216 1.00 27.31  ? 381 LEU D N   1 
ATOM   13684 C CA  . LEU D 1 381 ? 11.494  66.919  -12.339 1.00 26.22  ? 381 LEU D CA  1 
ATOM   13685 C C   . LEU D 1 381 ? 11.730  66.084  -11.090 1.00 26.52  ? 381 LEU D C   1 
ATOM   13686 O O   . LEU D 1 381 ? 11.971  64.887  -11.196 1.00 27.17  ? 381 LEU D O   1 
ATOM   13687 C CB  . LEU D 1 381 ? 12.665  67.863  -12.577 1.00 27.62  ? 381 LEU D CB  1 
ATOM   13688 C CG  . LEU D 1 381 ? 12.583  68.747  -13.827 1.00 25.54  ? 381 LEU D CG  1 
ATOM   13689 C CD1 . LEU D 1 381 ? 13.774  69.668  -13.894 1.00 26.51  ? 381 LEU D CD1 1 
ATOM   13690 C CD2 . LEU D 1 381 ? 12.492  67.932  -15.085 1.00 24.41  ? 381 LEU D CD2 1 
ATOM   13691 N N   . LEU D 1 382 ? 11.618  66.711  -9.903  1.00 26.47  ? 382 LEU D N   1 
ATOM   13692 C CA  . LEU D 1 382 ? 11.866  65.995  -8.665  1.00 23.09  ? 382 LEU D CA  1 
ATOM   13693 C C   . LEU D 1 382 ? 10.854  64.863  -8.496  1.00 23.01  ? 382 LEU D C   1 
ATOM   13694 O O   . LEU D 1 382 ? 11.238  63.716  -8.195  1.00 21.45  ? 382 LEU D O   1 
ATOM   13695 C CB  . LEU D 1 382 ? 11.849  66.964  -7.497  1.00 22.80  ? 382 LEU D CB  1 
ATOM   13696 C CG  . LEU D 1 382 ? 12.955  68.008  -7.497  1.00 22.22  ? 382 LEU D CG  1 
ATOM   13697 C CD1 . LEU D 1 382 ? 12.583  69.176  -6.599  1.00 24.16  ? 382 LEU D CD1 1 
ATOM   13698 C CD2 . LEU D 1 382 ? 14.206  67.344  -7.070  1.00 20.51  ? 382 LEU D CD2 1 
ATOM   13699 N N   . TRP D 1 383 ? 9.574   65.198  -8.722  1.00 24.20  ? 383 TRP D N   1 
ATOM   13700 C CA  . TRP D 1 383 ? 8.492   64.231  -8.624  1.00 24.58  ? 383 TRP D CA  1 
ATOM   13701 C C   . TRP D 1 383 ? 8.758   63.063  -9.558  1.00 26.99  ? 383 TRP D C   1 
ATOM   13702 O O   . TRP D 1 383 ? 8.590   61.927  -9.128  1.00 29.55  ? 383 TRP D O   1 
ATOM   13703 C CB  . TRP D 1 383 ? 7.128   64.854  -8.930  1.00 25.53  ? 383 TRP D CB  1 
ATOM   13704 C CG  . TRP D 1 383 ? 5.963   63.948  -8.629  1.00 27.84  ? 383 TRP D CG  1 
ATOM   13705 C CD1 . TRP D 1 383 ? 5.395   63.048  -9.481  1.00 31.97  ? 383 TRP D CD1 1 
ATOM   13706 C CD2 . TRP D 1 383 ? 5.206   63.851  -7.399  1.00 31.86  ? 383 TRP D CD2 1 
ATOM   13707 N NE1 . TRP D 1 383 ? 4.346   62.403  -8.879  1.00 31.65  ? 383 TRP D NE1 1 
ATOM   13708 C CE2 . TRP D 1 383 ? 4.209   62.869  -7.603  1.00 32.28  ? 383 TRP D CE2 1 
ATOM   13709 C CE3 . TRP D 1 383 ? 5.262   64.486  -6.151  1.00 32.16  ? 383 TRP D CE3 1 
ATOM   13710 C CZ2 . TRP D 1 383 ? 3.294   62.519  -6.615  1.00 32.86  ? 383 TRP D CZ2 1 
ATOM   13711 C CZ3 . TRP D 1 383 ? 4.352   64.137  -5.176  1.00 33.27  ? 383 TRP D CZ3 1 
ATOM   13712 C CH2 . TRP D 1 383 ? 3.383   63.166  -5.408  1.00 32.20  ? 383 TRP D CH2 1 
ATOM   13713 N N   . HIS D 1 384 ? 9.182   63.332  -10.812 1.00 28.55  ? 384 HIS D N   1 
ATOM   13714 C CA  . HIS D 1 384 ? 9.436   62.259  -11.760 1.00 28.72  ? 384 HIS D CA  1 
ATOM   13715 C C   . HIS D 1 384 ? 10.408  61.219  -11.203 1.00 28.86  ? 384 HIS D C   1 
ATOM   13716 O O   . HIS D 1 384 ? 10.238  60.032  -11.465 1.00 32.27  ? 384 HIS D O   1 
ATOM   13717 C CB  . HIS D 1 384 ? 9.975   62.786  -13.090 1.00 34.08  ? 384 HIS D CB  1 
ATOM   13718 C CG  . HIS D 1 384 ? 10.385  61.716  -14.063 1.00 35.46  ? 384 HIS D CG  1 
ATOM   13719 N ND1 . HIS D 1 384 ? 9.513   61.124  -14.951 1.00 34.26  ? 384 HIS D ND1 1 
ATOM   13720 C CD2 . HIS D 1 384 ? 11.582  61.157  -14.294 1.00 35.95  ? 384 HIS D CD2 1 
ATOM   13721 C CE1 . HIS D 1 384 ? 10.170  60.246  -15.690 1.00 36.64  ? 384 HIS D CE1 1 
ATOM   13722 N NE2 . HIS D 1 384 ? 11.433  60.246  -15.313 1.00 38.03  ? 384 HIS D NE2 1 
ATOM   13723 N N   . TYR D 1 385 ? 11.440  61.637  -10.457 1.00 28.50  ? 385 TYR D N   1 
ATOM   13724 C CA  . TYR D 1 385 ? 12.477  60.695  -10.048 1.00 28.32  ? 385 TYR D CA  1 
ATOM   13725 C C   . TYR D 1 385 ? 12.228  60.094  -8.666  1.00 30.12  ? 385 TYR D C   1 
ATOM   13726 O O   . TYR D 1 385 ? 13.032  59.286  -8.208  1.00 32.20  ? 385 TYR D O   1 
ATOM   13727 C CB  . TYR D 1 385 ? 13.828  61.399  -10.098 1.00 26.06  ? 385 TYR D CB  1 
ATOM   13728 C CG  . TYR D 1 385 ? 14.282  61.597  -11.526 1.00 26.18  ? 385 TYR D CG  1 
ATOM   13729 C CD1 . TYR D 1 385 ? 14.667  60.507  -12.300 1.00 25.39  ? 385 TYR D CD1 1 
ATOM   13730 C CD2 . TYR D 1 385 ? 14.312  62.865  -12.108 1.00 31.47  ? 385 TYR D CD2 1 
ATOM   13731 C CE1 . TYR D 1 385 ? 15.069  60.659  -13.616 1.00 25.05  ? 385 TYR D CE1 1 
ATOM   13732 C CE2 . TYR D 1 385 ? 14.714  63.036  -13.430 1.00 30.68  ? 385 TYR D CE2 1 
ATOM   13733 C CZ  . TYR D 1 385 ? 15.109  61.928  -14.176 1.00 27.98  ? 385 TYR D CZ  1 
ATOM   13734 O OH  . TYR D 1 385 ? 15.564  62.080  -15.452 1.00 28.64  ? 385 TYR D OH  1 
ATOM   13735 N N   . GLY D 1 386 ? 11.137  60.491  -7.999  1.00 30.81  ? 386 GLY D N   1 
ATOM   13736 C CA  . GLY D 1 386 ? 10.706  59.840  -6.767  1.00 31.38  ? 386 GLY D CA  1 
ATOM   13737 C C   . GLY D 1 386 ? 10.957  60.694  -5.520  1.00 31.61  ? 386 GLY D C   1 
ATOM   13738 O O   . GLY D 1 386 ? 10.867  60.194  -4.407  1.00 32.86  ? 386 GLY D O   1 
ATOM   13739 N N   . ILE D 1 387 ? 11.307  61.972  -5.713  1.00 33.31  ? 387 ILE D N   1 
ATOM   13740 C CA  . ILE D 1 387 ? 11.403  62.944  -4.632  1.00 33.81  ? 387 ILE D CA  1 
ATOM   13741 C C   . ILE D 1 387 ? 10.083  63.723  -4.577  1.00 33.81  ? 387 ILE D C   1 
ATOM   13742 O O   . ILE D 1 387 ? 9.860   64.654  -5.364  1.00 28.88  ? 387 ILE D O   1 
ATOM   13743 C CB  . ILE D 1 387 ? 12.632  63.867  -4.789  1.00 31.34  ? 387 ILE D CB  1 
ATOM   13744 C CG1 . ILE D 1 387 ? 13.975  63.107  -4.817  1.00 33.81  ? 387 ILE D CG1 1 
ATOM   13745 C CG2 . ILE D 1 387 ? 12.634  64.929  -3.699  1.00 34.54  ? 387 ILE D CG2 1 
ATOM   13746 C CD1 . ILE D 1 387 ? 14.711  63.084  -6.154  1.00 32.97  ? 387 ILE D CD1 1 
ATOM   13747 N N   . ARG D 1 388 ? 9.219   63.301  -3.636  1.00 35.06  ? 388 ARG D N   1 
ATOM   13748 C CA  . ARG D 1 388 ? 7.828   63.734  -3.581  1.00 37.85  ? 388 ARG D CA  1 
ATOM   13749 C C   . ARG D 1 388 ? 7.498   64.403  -2.254  1.00 34.62  ? 388 ARG D C   1 
ATOM   13750 O O   . ARG D 1 388 ? 6.345   64.734  -2.007  1.00 31.99  ? 388 ARG D O   1 
ATOM   13751 C CB  . ARG D 1 388 ? 6.886   62.539  -3.731  1.00 42.46  ? 388 ARG D CB  1 
ATOM   13752 C CG  . ARG D 1 388 ? 7.248   61.797  -5.001  1.00 46.38  ? 388 ARG D CG  1 
ATOM   13753 C CD  . ARG D 1 388 ? 6.265   60.740  -5.379  1.00 54.37  ? 388 ARG D CD  1 
ATOM   13754 N NE  . ARG D 1 388 ? 6.666   60.367  -6.744  1.00 59.18  ? 388 ARG D NE  1 
ATOM   13755 C CZ  . ARG D 1 388 ? 5.959   59.626  -7.573  1.00 51.35  ? 388 ARG D CZ  1 
ATOM   13756 N NH1 . ARG D 1 388 ? 4.807   59.103  -7.168  1.00 56.33  ? 388 ARG D NH1 1 
ATOM   13757 N NH2 . ARG D 1 388 ? 6.403   59.445  -8.798  1.00 46.51  ? 388 ARG D NH2 1 
ATOM   13758 N N   . GLU D 1 389 ? 8.518   64.658  -1.431  1.00 33.56  ? 389 GLU D N   1 
ATOM   13759 C CA  . GLU D 1 389 ? 8.291   65.271  -0.141  1.00 29.12  ? 389 GLU D CA  1 
ATOM   13760 C C   . GLU D 1 389 ? 8.262   66.780  -0.315  1.00 29.32  ? 389 GLU D C   1 
ATOM   13761 O O   . GLU D 1 389 ? 9.275   67.445  -0.118  1.00 27.23  ? 389 GLU D O   1 
ATOM   13762 C CB  . GLU D 1 389 ? 9.366   64.751  0.790   1.00 27.17  ? 389 GLU D CB  1 
ATOM   13763 C CG  . GLU D 1 389 ? 9.152   63.283  1.111   1.00 26.35  ? 389 GLU D CG  1 
ATOM   13764 C CD  . GLU D 1 389 ? 9.579   62.345  0.009   1.00 28.06  ? 389 GLU D CD  1 
ATOM   13765 O OE1 . GLU D 1 389 ? 9.223   61.149  0.156   1.00 30.32  ? 389 GLU D OE1 1 
ATOM   13766 O OE2 . GLU D 1 389 ? 10.265  62.759  -0.947  1.00 26.08  ? 389 GLU D OE2 1 
ATOM   13767 N N   . TYR D 1 390 ? 7.069   67.291  -0.658  1.00 29.44  ? 390 TYR D N   1 
ATOM   13768 C CA  . TYR D 1 390 ? 6.906   68.680  -1.067  1.00 30.77  ? 390 TYR D CA  1 
ATOM   13769 C C   . TYR D 1 390 ? 7.682   69.641  -0.161  1.00 29.91  ? 390 TYR D C   1 
ATOM   13770 O O   . TYR D 1 390 ? 8.444   70.462  -0.655  1.00 28.32  ? 390 TYR D O   1 
ATOM   13771 C CB  . TYR D 1 390 ? 5.434   69.110  -1.042  1.00 32.83  ? 390 TYR D CB  1 
ATOM   13772 C CG  . TYR D 1 390 ? 4.480   68.300  -1.910  1.00 31.29  ? 390 TYR D CG  1 
ATOM   13773 C CD1 . TYR D 1 390 ? 4.256   68.648  -3.238  1.00 28.33  ? 390 TYR D CD1 1 
ATOM   13774 C CD2 . TYR D 1 390 ? 3.779   67.221  -1.392  1.00 29.22  ? 390 TYR D CD2 1 
ATOM   13775 C CE1 . TYR D 1 390 ? 3.359   67.951  -4.019  1.00 27.15  ? 390 TYR D CE1 1 
ATOM   13776 C CE2 . TYR D 1 390 ? 2.907   66.496  -2.175  1.00 29.53  ? 390 TYR D CE2 1 
ATOM   13777 C CZ  . TYR D 1 390 ? 2.684   66.873  -3.490  1.00 28.47  ? 390 TYR D CZ  1 
ATOM   13778 O OH  . TYR D 1 390 ? 1.836   66.169  -4.295  1.00 27.90  ? 390 TYR D OH  1 
ATOM   13779 N N   . ASP D 1 391 ? 7.471   69.562  1.164   1.00 28.06  ? 391 ASP D N   1 
ATOM   13780 C CA  . ASP D 1 391 ? 8.011   70.559  2.085   1.00 28.75  ? 391 ASP D CA  1 
ATOM   13781 C C   . ASP D 1 391 ? 9.545   70.595  2.034   1.00 27.91  ? 391 ASP D C   1 
ATOM   13782 O O   . ASP D 1 391 ? 10.173  71.639  2.275   1.00 25.65  ? 391 ASP D O   1 
ATOM   13783 C CB  . ASP D 1 391 ? 7.504   70.296  3.496   1.00 30.08  ? 391 ASP D CB  1 
ATOM   13784 C CG  . ASP D 1 391 ? 6.048   70.648  3.768   1.00 29.61  ? 391 ASP D CG  1 
ATOM   13785 O OD1 . ASP D 1 391 ? 5.384   71.166  2.873   1.00 27.84  ? 391 ASP D OD1 1 
ATOM   13786 O OD2 . ASP D 1 391 ? 5.610   70.453  4.903   1.00 30.05  ? 391 ASP D OD2 1 
ATOM   13787 N N   . PHE D 1 392 ? 10.130  69.432  1.722   1.00 25.40  ? 392 PHE D N   1 
ATOM   13788 C CA  . PHE D 1 392 ? 11.571  69.259  1.686   1.00 26.33  ? 392 PHE D CA  1 
ATOM   13789 C C   . PHE D 1 392 ? 12.177  69.976  0.478   1.00 26.35  ? 392 PHE D C   1 
ATOM   13790 O O   . PHE D 1 392 ? 13.381  70.190  0.465   1.00 23.87  ? 392 PHE D O   1 
ATOM   13791 C CB  . PHE D 1 392 ? 11.943  67.765  1.651   1.00 25.78  ? 392 PHE D CB  1 
ATOM   13792 C CG  . PHE D 1 392 ? 13.422  67.495  1.901   1.00 24.85  ? 392 PHE D CG  1 
ATOM   13793 C CD1 . PHE D 1 392 ? 13.957  67.596  3.180   1.00 22.71  ? 392 PHE D CD1 1 
ATOM   13794 C CD2 . PHE D 1 392 ? 14.283  67.179  0.851   1.00 24.18  ? 392 PHE D CD2 1 
ATOM   13795 C CE1 . PHE D 1 392 ? 15.304  67.359  3.401   1.00 24.43  ? 392 PHE D CE1 1 
ATOM   13796 C CE2 . PHE D 1 392 ? 15.636  66.964  1.075   1.00 23.40  ? 392 PHE D CE2 1 
ATOM   13797 C CZ  . PHE D 1 392 ? 16.143  67.046  2.351   1.00 25.50  ? 392 PHE D CZ  1 
ATOM   13798 N N   . TYR D 1 393 ? 11.366  70.341  -0.538  1.00 28.53  ? 393 TYR D N   1 
ATOM   13799 C CA  . TYR D 1 393 ? 11.896  70.946  -1.767  1.00 28.99  ? 393 TYR D CA  1 
ATOM   13800 C C   . TYR D 1 393 ? 12.712  72.208  -1.430  1.00 28.14  ? 393 TYR D C   1 
ATOM   13801 O O   . TYR D 1 393 ? 13.774  72.466  -2.018  1.00 24.93  ? 393 TYR D O   1 
ATOM   13802 C CB  . TYR D 1 393 ? 10.788  71.238  -2.803  1.00 28.39  ? 393 TYR D CB  1 
ATOM   13803 C CG  . TYR D 1 393 ? 10.115  70.062  -3.523  1.00 29.11  ? 393 TYR D CG  1 
ATOM   13804 C CD1 . TYR D 1 393 ? 10.519  68.743  -3.323  1.00 27.91  ? 393 TYR D CD1 1 
ATOM   13805 C CD2 . TYR D 1 393 ? 9.101   70.279  -4.463  1.00 29.52  ? 393 TYR D CD2 1 
ATOM   13806 C CE1 . TYR D 1 393 ? 9.912   67.693  -3.997  1.00 29.34  ? 393 TYR D CE1 1 
ATOM   13807 C CE2 . TYR D 1 393 ? 8.474   69.233  -5.126  1.00 26.77  ? 393 TYR D CE2 1 
ATOM   13808 C CZ  . TYR D 1 393 ? 8.879   67.936  -4.884  1.00 26.29  ? 393 TYR D CZ  1 
ATOM   13809 O OH  . TYR D 1 393 ? 8.340   66.873  -5.523  1.00 23.71  ? 393 TYR D OH  1 
ATOM   13810 N N   . THR D 1 394 ? 12.215  72.978  -0.443  1.00 25.64  ? 394 THR D N   1 
ATOM   13811 C CA  . THR D 1 394 ? 12.825  74.233  -0.060  1.00 24.37  ? 394 THR D CA  1 
ATOM   13812 C C   . THR D 1 394 ? 14.179  73.982  0.617   1.00 27.82  ? 394 THR D C   1 
ATOM   13813 O O   . THR D 1 394 ? 15.052  74.853  0.603   1.00 26.32  ? 394 THR D O   1 
ATOM   13814 C CB  . THR D 1 394 ? 11.837  74.992  0.813   1.00 22.57  ? 394 THR D CB  1 
ATOM   13815 O OG1 . THR D 1 394 ? 10.632  74.977  0.060   1.00 21.35  ? 394 THR D OG1 1 
ATOM   13816 C CG2 . THR D 1 394 ? 12.256  76.432  1.002   1.00 22.87  ? 394 THR D CG2 1 
ATOM   13817 N N   . VAL D 1 395 ? 14.387  72.773  1.164   1.00 27.94  ? 395 VAL D N   1 
ATOM   13818 C CA  . VAL D 1 395 ? 15.685  72.421  1.716   1.00 27.60  ? 395 VAL D CA  1 
ATOM   13819 C C   . VAL D 1 395 ? 16.703  72.279  0.578   1.00 25.82  ? 395 VAL D C   1 
ATOM   13820 O O   . VAL D 1 395 ? 17.784  72.909  0.605   1.00 23.38  ? 395 VAL D O   1 
ATOM   13821 C CB  . VAL D 1 395 ? 15.614  71.169  2.612   1.00 27.54  ? 395 VAL D CB  1 
ATOM   13822 C CG1 . VAL D 1 395 ? 16.998  70.703  3.046   1.00 28.05  ? 395 VAL D CG1 1 
ATOM   13823 C CG2 . VAL D 1 395 ? 14.744  71.419  3.834   1.00 26.50  ? 395 VAL D CG2 1 
ATOM   13824 N N   . LEU D 1 396 ? 16.353  71.481  -0.438  1.00 23.22  ? 396 LEU D N   1 
ATOM   13825 C CA  . LEU D 1 396 ? 17.188  71.441  -1.629  1.00 22.15  ? 396 LEU D CA  1 
ATOM   13826 C C   . LEU D 1 396 ? 17.499  72.869  -2.071  1.00 20.04  ? 396 LEU D C   1 
ATOM   13827 O O   . LEU D 1 396 ? 18.631  73.219  -2.361  1.00 21.08  ? 396 LEU D O   1 
ATOM   13828 C CB  . LEU D 1 396 ? 16.522  70.647  -2.743  1.00 23.73  ? 396 LEU D CB  1 
ATOM   13829 C CG  . LEU D 1 396 ? 16.159  69.202  -2.403  1.00 23.44  ? 396 LEU D CG  1 
ATOM   13830 C CD1 . LEU D 1 396 ? 15.416  68.666  -3.588  1.00 25.45  ? 396 LEU D CD1 1 
ATOM   13831 C CD2 . LEU D 1 396 ? 17.383  68.373  -2.085  1.00 22.58  ? 396 LEU D CD2 1 
ATOM   13832 N N   . PHE D 1 397 ? 16.502  73.736  -2.095  1.00 19.70  ? 397 PHE D N   1 
ATOM   13833 C CA  . PHE D 1 397 ? 16.764  75.099  -2.508  1.00 21.29  ? 397 PHE D CA  1 
ATOM   13834 C C   . PHE D 1 397 ? 17.850  75.677  -1.609  1.00 23.14  ? 397 PHE D C   1 
ATOM   13835 O O   . PHE D 1 397 ? 18.798  76.303  -2.084  1.00 23.84  ? 397 PHE D O   1 
ATOM   13836 C CB  . PHE D 1 397 ? 15.466  75.902  -2.421  1.00 23.16  ? 397 PHE D CB  1 
ATOM   13837 C CG  . PHE D 1 397 ? 15.416  77.226  -3.160  1.00 24.80  ? 397 PHE D CG  1 
ATOM   13838 C CD1 . PHE D 1 397 ? 16.565  77.884  -3.574  1.00 27.89  ? 397 PHE D CD1 1 
ATOM   13839 C CD2 . PHE D 1 397 ? 14.198  77.839  -3.384  1.00 28.67  ? 397 PHE D CD2 1 
ATOM   13840 C CE1 . PHE D 1 397 ? 16.494  79.108  -4.223  1.00 28.23  ? 397 PHE D CE1 1 
ATOM   13841 C CE2 . PHE D 1 397 ? 14.131  79.063  -4.030  1.00 31.11  ? 397 PHE D CE2 1 
ATOM   13842 C CZ  . PHE D 1 397 ? 15.281  79.695  -4.443  1.00 30.44  ? 397 PHE D CZ  1 
ATOM   13843 N N   . GLY D 1 398 ? 17.665  75.469  -0.296  1.00 25.40  ? 398 GLY D N   1 
ATOM   13844 C CA  . GLY D 1 398 ? 18.535  76.011  0.725   1.00 22.92  ? 398 GLY D CA  1 
ATOM   13845 C C   . GLY D 1 398 ? 19.977  75.567  0.515   1.00 22.41  ? 398 GLY D C   1 
ATOM   13846 O O   . GLY D 1 398 ? 20.877  76.407  0.556   1.00 22.78  ? 398 GLY D O   1 
ATOM   13847 N N   . VAL D 1 399 ? 20.167  74.254  0.291   1.00 21.62  ? 399 VAL D N   1 
ATOM   13848 C CA  . VAL D 1 399 ? 21.491  73.717  0.046   1.00 21.56  ? 399 VAL D CA  1 
ATOM   13849 C C   . VAL D 1 399 ? 22.124  74.441  -1.149  1.00 24.72  ? 399 VAL D C   1 
ATOM   13850 O O   . VAL D 1 399 ? 23.287  74.848  -1.068  1.00 25.13  ? 399 VAL D O   1 
ATOM   13851 C CB  . VAL D 1 399 ? 21.435  72.195  -0.143  1.00 21.21  ? 399 VAL D CB  1 
ATOM   13852 C CG1 . VAL D 1 399 ? 22.788  71.623  -0.512  1.00 21.51  ? 399 VAL D CG1 1 
ATOM   13853 C CG2 . VAL D 1 399 ? 20.907  71.478  1.092   1.00 21.70  ? 399 VAL D CG2 1 
ATOM   13854 N N   . SER D 1 400 ? 21.359  74.670  -2.231  1.00 24.65  ? 400 SER D N   1 
ATOM   13855 C CA  . SER D 1 400 ? 21.917  75.321  -3.416  1.00 26.99  ? 400 SER D CA  1 
ATOM   13856 C C   . SER D 1 400 ? 22.280  76.771  -3.117  1.00 27.00  ? 400 SER D C   1 
ATOM   13857 O O   . SER D 1 400 ? 23.393  77.195  -3.424  1.00 28.67  ? 400 SER D O   1 
ATOM   13858 C CB  . SER D 1 400 ? 21.000  75.264  -4.639  1.00 27.28  ? 400 SER D CB  1 
ATOM   13859 O OG  . SER D 1 400 ? 21.464  76.077  -5.716  1.00 23.09  ? 400 SER D OG  1 
ATOM   13860 N N   . ARG D 1 401 ? 21.319  77.503  -2.553  1.00 23.66  ? 401 ARG D N   1 
ATOM   13861 C CA  . ARG D 1 401 ? 21.443  78.927  -2.315  1.00 24.78  ? 401 ARG D CA  1 
ATOM   13862 C C   . ARG D 1 401 ? 22.583  79.247  -1.353  1.00 25.85  ? 401 ARG D C   1 
ATOM   13863 O O   . ARG D 1 401 ? 23.099  80.368  -1.382  1.00 26.53  ? 401 ARG D O   1 
ATOM   13864 C CB  . ARG D 1 401 ? 20.092  79.452  -1.807  1.00 27.05  ? 401 ARG D CB  1 
ATOM   13865 C CG  . ARG D 1 401 ? 19.988  80.968  -1.692  1.00 27.10  ? 401 ARG D CG  1 
ATOM   13866 C CD  . ARG D 1 401 ? 20.653  81.739  -2.850  1.00 27.27  ? 401 ARG D CD  1 
ATOM   13867 N NE  . ARG D 1 401 ? 19.953  81.564  -4.125  1.00 27.90  ? 401 ARG D NE  1 
ATOM   13868 C CZ  . ARG D 1 401 ? 18.806  82.178  -4.450  1.00 29.38  ? 401 ARG D CZ  1 
ATOM   13869 N NH1 . ARG D 1 401 ? 18.225  83.030  -3.622  1.00 30.79  ? 401 ARG D NH1 1 
ATOM   13870 N NH2 . ARG D 1 401 ? 18.217  81.922  -5.603  1.00 29.14  ? 401 ARG D NH2 1 
ATOM   13871 N N   . ALA D 1 402 ? 22.984  78.267  -0.522  1.00 26.96  ? 402 ALA D N   1 
ATOM   13872 C CA  . ALA D 1 402 ? 24.201  78.359  0.290   1.00 27.35  ? 402 ALA D CA  1 
ATOM   13873 C C   . ALA D 1 402 ? 25.428  78.726  -0.553  1.00 26.74  ? 402 ALA D C   1 
ATOM   13874 O O   . ALA D 1 402 ? 26.358  79.381  -0.058  1.00 24.61  ? 402 ALA D O   1 
ATOM   13875 C CB  . ALA D 1 402 ? 24.446  77.056  1.057   1.00 26.49  ? 402 ALA D CB  1 
ATOM   13876 N N   . LEU D 1 403 ? 25.433  78.276  -1.821  1.00 27.18  ? 403 LEU D N   1 
ATOM   13877 C CA  . LEU D 1 403 ? 26.561  78.503  -2.718  1.00 28.50  ? 403 LEU D CA  1 
ATOM   13878 C C   . LEU D 1 403 ? 26.784  79.995  -2.945  1.00 23.82  ? 403 LEU D C   1 
ATOM   13879 O O   . LEU D 1 403 ? 27.904  80.467  -2.883  1.00 23.85  ? 403 LEU D O   1 
ATOM   13880 C CB  . LEU D 1 403 ? 26.352  77.750  -4.032  1.00 28.65  ? 403 LEU D CB  1 
ATOM   13881 C CG  . LEU D 1 403 ? 26.397  76.226  -3.907  1.00 27.49  ? 403 LEU D CG  1 
ATOM   13882 C CD1 . LEU D 1 403 ? 25.898  75.554  -5.161  1.00 28.22  ? 403 LEU D CD1 1 
ATOM   13883 C CD2 . LEU D 1 403 ? 27.807  75.785  -3.589  1.00 26.97  ? 403 LEU D CD2 1 
ATOM   13884 N N   . GLY D 1 404 ? 25.706  80.721  -3.195  1.00 22.49  ? 404 GLY D N   1 
ATOM   13885 C CA  . GLY D 1 404 ? 25.782  82.143  -3.447  1.00 22.94  ? 404 GLY D CA  1 
ATOM   13886 C C   . GLY D 1 404 ? 25.923  82.927  -2.151  1.00 23.20  ? 404 GLY D C   1 
ATOM   13887 O O   . GLY D 1 404 ? 26.548  83.982  -2.121  1.00 23.76  ? 404 GLY D O   1 
ATOM   13888 N N   . CYS D 1 405 ? 25.340  82.399  -1.071  1.00 26.36  ? 405 CYS D N   1 
ATOM   13889 C CA  . CYS D 1 405 ? 25.370  83.097  0.210   1.00 23.87  ? 405 CYS D CA  1 
ATOM   13890 C C   . CYS D 1 405 ? 26.793  83.124  0.759   1.00 22.78  ? 405 CYS D C   1 
ATOM   13891 O O   . CYS D 1 405 ? 27.275  84.180  1.196   1.00 20.86  ? 405 CYS D O   1 
ATOM   13892 C CB  . CYS D 1 405 ? 24.344  82.502  1.162   1.00 24.77  ? 405 CYS D CB  1 
ATOM   13893 S SG  . CYS D 1 405 ? 22.643  83.033  0.830   1.00 25.30  ? 405 CYS D SG  1 
ATOM   13894 N N   . THR D 1 406 ? 27.464  81.961  0.680   1.00 21.51  ? 406 THR D N   1 
ATOM   13895 C CA  . THR D 1 406 ? 28.832  81.853  1.148   1.00 22.07  ? 406 THR D CA  1 
ATOM   13896 C C   . THR D 1 406 ? 29.719  82.775  0.329   1.00 24.01  ? 406 THR D C   1 
ATOM   13897 O O   . THR D 1 406 ? 30.442  83.575  0.904   1.00 25.68  ? 406 THR D O   1 
ATOM   13898 C CB  . THR D 1 406 ? 29.322  80.406  1.121   1.00 23.06  ? 406 THR D CB  1 
ATOM   13899 O OG1 . THR D 1 406 ? 28.969  79.856  -0.143  1.00 19.61  ? 406 THR D OG1 1 
ATOM   13900 C CG2 . THR D 1 406 ? 28.714  79.615  2.271   1.00 23.83  ? 406 THR D CG2 1 
ATOM   13901 N N   . ALA D 1 407 ? 29.620  82.700  -1.009  1.00 25.93  ? 407 ALA D N   1 
ATOM   13902 C CA  . ALA D 1 407 ? 30.493  83.475  -1.880  1.00 26.31  ? 407 ALA D CA  1 
ATOM   13903 C C   . ALA D 1 407 ? 30.385  84.981  -1.607  1.00 23.46  ? 407 ALA D C   1 
ATOM   13904 O O   . ALA D 1 407 ? 31.409  85.667  -1.522  1.00 21.19  ? 407 ALA D O   1 
ATOM   13905 C CB  . ALA D 1 407 ? 30.221  83.135  -3.347  1.00 28.15  ? 407 ALA D CB  1 
ATOM   13906 N N   . GLN D 1 408 ? 29.144  85.478  -1.503  1.00 24.23  ? 408 GLN D N   1 
ATOM   13907 C CA  . GLN D 1 408 ? 28.859  86.886  -1.248  1.00 27.61  ? 408 GLN D CA  1 
ATOM   13908 C C   . GLN D 1 408 ? 29.387  87.345  0.116   1.00 28.29  ? 408 GLN D C   1 
ATOM   13909 O O   . GLN D 1 408 ? 29.909  88.463  0.242   1.00 26.33  ? 408 GLN D O   1 
ATOM   13910 C CB  . GLN D 1 408 ? 27.343  87.095  -1.266  1.00 29.38  ? 408 GLN D CB  1 
ATOM   13911 C CG  . GLN D 1 408 ? 26.723  87.089  -2.661  1.00 28.85  ? 408 GLN D CG  1 
ATOM   13912 C CD  . GLN D 1 408 ? 25.277  87.551  -2.673  1.00 28.31  ? 408 GLN D CD  1 
ATOM   13913 O OE1 . GLN D 1 408 ? 24.902  88.552  -2.065  1.00 26.88  ? 408 GLN D OE1 1 
ATOM   13914 N NE2 . GLN D 1 408 ? 24.426  86.828  -3.378  1.00 31.46  ? 408 GLN D NE2 1 
ATOM   13915 N N   . ALA D 1 409 ? 29.220  86.503  1.151   1.00 26.40  ? 409 ALA D N   1 
ATOM   13916 C CA  . ALA D 1 409 ? 29.635  86.904  2.498   1.00 26.40  ? 409 ALA D CA  1 
ATOM   13917 C C   . ALA D 1 409 ? 31.158  86.970  2.567   1.00 25.12  ? 409 ALA D C   1 
ATOM   13918 O O   . ALA D 1 409 ? 31.726  87.848  3.223   1.00 24.18  ? 409 ALA D O   1 
ATOM   13919 C CB  . ALA D 1 409 ? 29.084  85.962  3.555   1.00 24.84  ? 409 ALA D CB  1 
ATOM   13920 N N   . ILE D 1 410 ? 31.811  86.039  1.863   1.00 24.36  ? 410 ILE D N   1 
ATOM   13921 C CA  . ILE D 1 410 ? 33.261  86.034  1.803   1.00 24.70  ? 410 ILE D CA  1 
ATOM   13922 C C   . ILE D 1 410 ? 33.744  87.303  1.126   1.00 23.70  ? 410 ILE D C   1 
ATOM   13923 O O   . ILE D 1 410 ? 34.700  87.911  1.581   1.00 25.74  ? 410 ILE D O   1 
ATOM   13924 C CB  . ILE D 1 410 ? 33.802  84.798  1.081   1.00 25.25  ? 410 ILE D CB  1 
ATOM   13925 C CG1 . ILE D 1 410 ? 33.483  83.523  1.881   1.00 27.55  ? 410 ILE D CG1 1 
ATOM   13926 C CG2 . ILE D 1 410 ? 35.309  84.981  0.805   1.00 24.47  ? 410 ILE D CG2 1 
ATOM   13927 C CD1 . ILE D 1 410 ? 33.662  82.231  1.095   1.00 28.75  ? 410 ILE D CD1 1 
ATOM   13928 N N   . LEU D 1 411 ? 33.088  87.663  0.028   1.00 24.30  ? 411 LEU D N   1 
ATOM   13929 C CA  . LEU D 1 411 ? 33.527  88.775  -0.802  1.00 25.52  ? 411 LEU D CA  1 
ATOM   13930 C C   . LEU D 1 411 ? 33.352  90.093  -0.053  1.00 25.44  ? 411 LEU D C   1 
ATOM   13931 O O   . LEU D 1 411 ? 34.265  90.904  -0.018  1.00 26.89  ? 411 LEU D O   1 
ATOM   13932 C CB  . LEU D 1 411 ? 32.730  88.755  -2.105  1.00 22.67  ? 411 LEU D CB  1 
ATOM   13933 C CG  . LEU D 1 411 ? 33.178  87.677  -3.075  1.00 22.76  ? 411 LEU D CG  1 
ATOM   13934 C CD1 . LEU D 1 411 ? 32.179  87.527  -4.179  1.00 22.26  ? 411 LEU D CD1 1 
ATOM   13935 C CD2 . LEU D 1 411 ? 34.590  88.027  -3.598  1.00 22.82  ? 411 LEU D CD2 1 
ATOM   13936 N N   . VAL D 1 412 ? 32.160  90.297  0.500   1.00 26.56  ? 412 VAL D N   1 
ATOM   13937 C CA  . VAL D 1 412 ? 31.803  91.536  1.171   1.00 32.35  ? 412 VAL D CA  1 
ATOM   13938 C C   . VAL D 1 412 ? 32.639  91.741  2.440   1.00 29.92  ? 412 VAL D C   1 
ATOM   13939 O O   . VAL D 1 412 ? 32.874  92.877  2.835   1.00 27.44  ? 412 VAL D O   1 
ATOM   13940 C CB  . VAL D 1 412 ? 30.286  91.559  1.457   1.00 38.12  ? 412 VAL D CB  1 
ATOM   13941 C CG1 . VAL D 1 412 ? 29.913  92.540  2.555   1.00 44.31  ? 412 VAL D CG1 1 
ATOM   13942 C CG2 . VAL D 1 412 ? 29.490  91.901  0.207   1.00 37.82  ? 412 VAL D CG2 1 
ATOM   13943 N N   . ARG D 1 413 ? 33.141  90.656  3.045   1.00 31.00  ? 413 ARG D N   1 
ATOM   13944 C CA  . ARG D 1 413 ? 34.079  90.777  4.159   1.00 31.04  ? 413 ARG D CA  1 
ATOM   13945 C C   . ARG D 1 413 ? 35.478  91.100  3.641   1.00 31.13  ? 413 ARG D C   1 
ATOM   13946 O O   . ARG D 1 413 ? 36.261  91.767  4.336   1.00 29.43  ? 413 ARG D O   1 
ATOM   13947 C CB  . ARG D 1 413 ? 34.033  89.523  5.046   1.00 31.00  ? 413 ARG D CB  1 
ATOM   13948 C CG  . ARG D 1 413 ? 32.704  89.344  5.784   1.00 28.58  ? 413 ARG D CG  1 
ATOM   13949 C CD  . ARG D 1 413 ? 32.681  90.045  7.120   1.00 28.88  ? 413 ARG D CD  1 
ATOM   13950 N NE  . ARG D 1 413 ? 32.990  91.481  7.110   1.00 29.95  ? 413 ARG D NE  1 
ATOM   13951 C CZ  . ARG D 1 413 ? 32.249  92.466  6.590   1.00 29.59  ? 413 ARG D CZ  1 
ATOM   13952 N NH1 . ARG D 1 413 ? 31.044  92.214  6.122   1.00 30.11  ? 413 ARG D NH1 1 
ATOM   13953 N NH2 . ARG D 1 413 ? 32.722  93.706  6.554   1.00 29.33  ? 413 ARG D NH2 1 
ATOM   13954 N N   . GLY D 1 414 ? 35.779  90.586  2.434   1.00 29.91  ? 414 GLY D N   1 
ATOM   13955 C CA  . GLY D 1 414 ? 37.000  90.927  1.725   1.00 26.61  ? 414 GLY D CA  1 
ATOM   13956 C C   . GLY D 1 414 ? 37.008  92.420  1.421   1.00 25.22  ? 414 GLY D C   1 
ATOM   13957 O O   . GLY D 1 414 ? 38.013  93.097  1.626   1.00 26.56  ? 414 GLY D O   1 
ATOM   13958 N N   . TYR D 1 415 ? 35.861  92.944  0.999   1.00 25.51  ? 415 TYR D N   1 
ATOM   13959 C CA  . TYR D 1 415 ? 35.773  94.349  0.625   1.00 27.51  ? 415 TYR D CA  1 
ATOM   13960 C C   . TYR D 1 415 ? 35.841  95.237  1.867   1.00 31.01  ? 415 TYR D C   1 
ATOM   13961 O O   . TYR D 1 415 ? 36.247  96.398  1.760   1.00 32.03  ? 415 TYR D O   1 
ATOM   13962 C CB  . TYR D 1 415 ? 34.474  94.718  -0.090  1.00 27.74  ? 415 TYR D CB  1 
ATOM   13963 C CG  . TYR D 1 415 ? 34.176  94.018  -1.403  1.00 25.94  ? 415 TYR D CG  1 
ATOM   13964 C CD1 . TYR D 1 415 ? 35.110  93.206  -2.022  1.00 27.22  ? 415 TYR D CD1 1 
ATOM   13965 C CD2 . TYR D 1 415 ? 32.955  94.196  -2.023  1.00 27.14  ? 415 TYR D CD2 1 
ATOM   13966 C CE1 . TYR D 1 415 ? 34.822  92.554  -3.207  1.00 27.67  ? 415 TYR D CE1 1 
ATOM   13967 C CE2 . TYR D 1 415 ? 32.656  93.568  -3.221  1.00 29.50  ? 415 TYR D CE2 1 
ATOM   13968 C CZ  . TYR D 1 415 ? 33.592  92.739  -3.808  1.00 29.73  ? 415 TYR D CZ  1 
ATOM   13969 O OH  . TYR D 1 415 ? 33.320  92.122  -4.982  1.00 34.57  ? 415 TYR D OH  1 
ATOM   13970 N N   . MET D 1 416 ? 35.385  94.682  3.011   1.00 32.15  ? 416 MET D N   1 
ATOM   13971 C CA  . MET D 1 416 ? 35.256  95.361  4.298   1.00 28.98  ? 416 MET D CA  1 
ATOM   13972 C C   . MET D 1 416 ? 34.130  96.388  4.263   1.00 27.38  ? 416 MET D C   1 
ATOM   13973 O O   . MET D 1 416 ? 34.261  97.491  4.790   1.00 26.30  ? 416 MET D O   1 
ATOM   13974 C CB  . MET D 1 416 ? 36.550  96.037  4.756   1.00 28.04  ? 416 MET D CB  1 
ATOM   13975 C CG  . MET D 1 416 ? 37.730  95.100  4.793   1.00 29.32  ? 416 MET D CG  1 
ATOM   13976 S SD  . MET D 1 416 ? 39.173  96.123  5.124   1.00 37.20  ? 416 MET D SD  1 
ATOM   13977 C CE  . MET D 1 416 ? 40.434  94.857  5.100   1.00 42.02  ? 416 MET D CE  1 
ATOM   13978 N N   . LEU D 1 417 ? 32.981  95.978  3.722   1.00 29.57  ? 417 LEU D N   1 
ATOM   13979 C CA  . LEU D 1 417 ? 31.795  96.816  3.753   1.00 29.30  ? 417 LEU D CA  1 
ATOM   13980 C C   . LEU D 1 417 ? 31.278  96.913  5.183   1.00 28.31  ? 417 LEU D C   1 
ATOM   13981 O O   . LEU D 1 417 ? 31.383  95.960  5.958   1.00 27.94  ? 417 LEU D O   1 
ATOM   13982 C CB  . LEU D 1 417 ? 30.766  96.217  2.801   1.00 32.05  ? 417 LEU D CB  1 
ATOM   13983 C CG  . LEU D 1 417 ? 31.192  96.133  1.332   1.00 30.79  ? 417 LEU D CG  1 
ATOM   13984 C CD1 . LEU D 1 417 ? 29.961  95.959  0.488   1.00 32.79  ? 417 LEU D CD1 1 
ATOM   13985 C CD2 . LEU D 1 417 ? 31.951  97.364  0.913   1.00 30.39  ? 417 LEU D CD2 1 
ATOM   13986 N N   . PRO D 1 418 ? 30.715  98.077  5.585   1.00 29.05  ? 418 PRO D N   1 
ATOM   13987 C CA  . PRO D 1 418 ? 30.290  98.285  6.964   1.00 28.39  ? 418 PRO D CA  1 
ATOM   13988 C C   . PRO D 1 418 ? 28.921  97.654  7.186   1.00 28.84  ? 418 PRO D C   1 
ATOM   13989 O O   . PRO D 1 418 ? 28.397  96.950  6.318   1.00 31.35  ? 418 PRO D O   1 
ATOM   13990 C CB  . PRO D 1 418 ? 30.287  99.814  7.099   1.00 27.78  ? 418 PRO D CB  1 
ATOM   13991 C CG  . PRO D 1 418 ? 29.888  100.283 5.725   1.00 27.96  ? 418 PRO D CG  1 
ATOM   13992 C CD  . PRO D 1 418 ? 30.460  99.260  4.752   1.00 27.94  ? 418 PRO D CD  1 
ATOM   13993 N N   . ILE D 1 419 ? 28.412  97.891  8.396   1.00 30.46  ? 419 ILE D N   1 
ATOM   13994 C CA  . ILE D 1 419 ? 27.147  97.379  8.884   1.00 29.69  ? 419 ILE D CA  1 
ATOM   13995 C C   . ILE D 1 419 ? 26.047  98.014  8.040   1.00 27.22  ? 419 ILE D C   1 
ATOM   13996 O O   . ILE D 1 419 ? 26.130  99.199  7.686   1.00 21.62  ? 419 ILE D O   1 
ATOM   13997 C CB  . ILE D 1 419 ? 27.005  97.657  10.405  1.00 30.17  ? 419 ILE D CB  1 
ATOM   13998 C CG1 . ILE D 1 419 ? 25.874  96.824  11.057  1.00 29.15  ? 419 ILE D CG1 1 
ATOM   13999 C CG2 . ILE D 1 419 ? 26.837  99.155  10.701  1.00 29.27  ? 419 ILE D CG2 1 
ATOM   14000 C CD1 . ILE D 1 419 ? 25.936  96.787  12.585  1.00 27.26  ? 419 ILE D CD1 1 
ATOM   14001 N N   . GLU D 1 420 ? 25.060  97.175  7.700   1.00 27.52  ? 420 GLU D N   1 
ATOM   14002 C CA  . GLU D 1 420 ? 23.847  97.595  7.026   1.00 27.53  ? 420 GLU D CA  1 
ATOM   14003 C C   . GLU D 1 420 ? 22.877  98.108  8.086   1.00 27.59  ? 420 GLU D C   1 
ATOM   14004 O O   . GLU D 1 420 ? 22.426  97.346  8.944   1.00 27.56  ? 420 GLU D O   1 
ATOM   14005 C CB  . GLU D 1 420 ? 23.267  96.427  6.221   1.00 26.89  ? 420 GLU D CB  1 
ATOM   14006 C CG  . GLU D 1 420 ? 21.985  96.791  5.481   1.00 24.98  ? 420 GLU D CG  1 
ATOM   14007 C CD  . GLU D 1 420 ? 21.396  95.631  4.724   1.00 25.33  ? 420 GLU D CD  1 
ATOM   14008 O OE1 . GLU D 1 420 ? 20.167  95.669  4.516   1.00 25.03  ? 420 GLU D OE1 1 
ATOM   14009 O OE2 . GLU D 1 420 ? 22.142  94.722  4.323   1.00 24.91  ? 420 GLU D OE2 1 
ATOM   14010 N N   . ARG D 1 421 ? 22.583  99.411  8.016   1.00 28.81  ? 421 ARG D N   1 
ATOM   14011 C CA  . ARG D 1 421 ? 21.752  100.094 8.994   1.00 28.52  ? 421 ARG D CA  1 
ATOM   14012 C C   . ARG D 1 421 ? 21.129  101.313 8.311   1.00 29.68  ? 421 ARG D C   1 
ATOM   14013 O O   . ARG D 1 421 ? 21.641  102.435 8.353   1.00 29.08  ? 421 ARG D O   1 
ATOM   14014 C CB  . ARG D 1 421 ? 22.605  100.421 10.219  1.00 29.33  ? 421 ARG D CB  1 
ATOM   14015 C CG  . ARG D 1 421 ? 21.854  100.271 11.527  1.00 31.93  ? 421 ARG D CG  1 
ATOM   14016 C CD  . ARG D 1 421 ? 21.267  101.562 12.048  1.00 32.90  ? 421 ARG D CD  1 
ATOM   14017 N NE  . ARG D 1 421 ? 19.835  101.753 11.871  1.00 33.62  ? 421 ARG D NE  1 
ATOM   14018 C CZ  . ARG D 1 421 ? 18.971  102.294 12.720  1.00 34.50  ? 421 ARG D CZ  1 
ATOM   14019 N NH1 . ARG D 1 421 ? 19.163  102.305 14.021  1.00 33.15  ? 421 ARG D NH1 1 
ATOM   14020 N NH2 . ARG D 1 421 ? 17.860  102.806 12.216  1.00 38.13  ? 421 ARG D NH2 1 
ATOM   14021 N N   . PRO D 1 422 ? 20.022  101.106 7.570   1.00 28.30  ? 422 PRO D N   1 
ATOM   14022 C CA  . PRO D 1 422 ? 19.364  102.207 6.877   1.00 27.21  ? 422 PRO D CA  1 
ATOM   14023 C C   . PRO D 1 422 ? 18.577  102.948 7.941   1.00 28.47  ? 422 PRO D C   1 
ATOM   14024 O O   . PRO D 1 422 ? 18.517  102.483 9.068   1.00 28.49  ? 422 PRO D O   1 
ATOM   14025 C CB  . PRO D 1 422 ? 18.483  101.495 5.850   1.00 25.86  ? 422 PRO D CB  1 
ATOM   14026 C CG  . PRO D 1 422 ? 18.121  100.217 6.560   1.00 26.16  ? 422 PRO D CG  1 
ATOM   14027 C CD  . PRO D 1 422 ? 19.371  99.803  7.347   1.00 26.08  ? 422 PRO D CD  1 
ATOM   14028 N N   . LYS D 1 423 ? 17.959  104.065 7.544   1.00 33.20  ? 423 LYS D N   1 
ATOM   14029 C CA  . LYS D 1 423 ? 17.125  104.889 8.400   1.00 34.32  ? 423 LYS D CA  1 
ATOM   14030 C C   . LYS D 1 423 ? 15.670  104.556 8.137   1.00 35.44  ? 423 LYS D C   1 
ATOM   14031 O O   . LYS D 1 423 ? 15.280  104.441 6.976   1.00 37.81  ? 423 LYS D O   1 
ATOM   14032 C CB  . LYS D 1 423 ? 17.323  106.369 8.050   1.00 36.64  ? 423 LYS D CB  1 
ATOM   14033 C CG  . LYS D 1 423 ? 16.673  107.390 8.983   1.00 37.18  ? 423 LYS D CG  1 
ATOM   14034 C CD  . LYS D 1 423 ? 17.257  107.423 10.395  1.00 36.27  ? 423 LYS D CD  1 
ATOM   14035 C CE  . LYS D 1 423 ? 16.747  108.553 11.240  1.00 35.25  ? 423 LYS D CE  1 
ATOM   14036 N NZ  . LYS D 1 423 ? 15.346  108.370 11.669  1.00 37.91  ? 423 LYS D NZ  1 
ATOM   14037 N N   . SER D 1 424 ? 14.879  104.469 9.213   1.00 36.12  ? 424 SER D N   1 
ATOM   14038 C CA  . SER D 1 424 ? 13.439  104.278 9.091   1.00 33.92  ? 424 SER D CA  1 
ATOM   14039 C C   . SER D 1 424 ? 12.710  105.621 9.208   1.00 31.12  ? 424 SER D C   1 
ATOM   14040 O O   . SER D 1 424 ? 13.301  106.640 9.570   1.00 30.66  ? 424 SER D O   1 
ATOM   14041 C CB  . SER D 1 424 ? 12.919  103.256 10.081  1.00 34.65  ? 424 SER D CB  1 
ATOM   14042 O OG  . SER D 1 424 ? 13.137  103.661 11.424  1.00 37.55  ? 424 SER D OG  1 
ATOM   14043 N N   . ILE D 1 425 ? 11.432  105.613 8.813   1.00 28.79  ? 425 ILE D N   1 
ATOM   14044 C CA  . ILE D 1 425 ? 10.591  106.796 8.809   1.00 28.62  ? 425 ILE D CA  1 
ATOM   14045 C C   . ILE D 1 425 ? 9.240   106.376 9.347   1.00 28.32  ? 425 ILE D C   1 
ATOM   14046 O O   . ILE D 1 425 ? 8.901   105.203 9.233   1.00 30.05  ? 425 ILE D O   1 
ATOM   14047 C CB  . ILE D 1 425 ? 10.441  107.387 7.395   1.00 28.31  ? 425 ILE D CB  1 
ATOM   14048 C CG1 . ILE D 1 425 ? 9.664   106.446 6.466   1.00 30.66  ? 425 ILE D CG1 1 
ATOM   14049 C CG2 . ILE D 1 425 ? 11.804  107.752 6.812   1.00 28.50  ? 425 ILE D CG2 1 
ATOM   14050 C CD1 . ILE D 1 425 ? 9.501   106.954 5.037   1.00 31.73  ? 425 ILE D CD1 1 
ATOM   14051 N N   . THR D 1 426 ? 8.482   107.357 9.854   1.00 29.23  ? 426 THR D N   1 
ATOM   14052 C CA  . THR D 1 426 ? 7.176   107.122 10.453  1.00 31.07  ? 426 THR D CA  1 
ATOM   14053 C C   . THR D 1 426 ? 6.076   107.603 9.506   1.00 32.05  ? 426 THR D C   1 
ATOM   14054 O O   . THR D 1 426 ? 6.269   108.530 8.709   1.00 30.01  ? 426 THR D O   1 
ATOM   14055 C CB  . THR D 1 426 ? 7.089   107.847 11.802  1.00 31.39  ? 426 THR D CB  1 
ATOM   14056 O OG1 . THR D 1 426 ? 7.144   109.240 11.500  1.00 30.47  ? 426 THR D OG1 1 
ATOM   14057 C CG2 . THR D 1 426 ? 8.233   107.490 12.737  1.00 30.20  ? 426 THR D CG2 1 
ATOM   14058 N N   . THR D 1 427 ? 4.890   107.002 9.655   1.00 33.81  ? 427 THR D N   1 
ATOM   14059 C CA  . THR D 1 427 ? 3.725   107.399 8.889   1.00 34.62  ? 427 THR D CA  1 
ATOM   14060 C C   . THR D 1 427 ? 3.303   108.814 9.294   1.00 37.07  ? 427 THR D C   1 
ATOM   14061 O O   . THR D 1 427 ? 2.799   109.559 8.449   1.00 38.63  ? 427 THR D O   1 
ATOM   14062 C CB  . THR D 1 427 ? 2.623   106.354 9.050   1.00 34.77  ? 427 THR D CB  1 
ATOM   14063 O OG1 . THR D 1 427 ? 3.186   105.159 8.518   1.00 31.76  ? 427 THR D OG1 1 
ATOM   14064 C CG2 . THR D 1 427 ? 1.395   106.666 8.214   1.00 35.45  ? 427 THR D CG2 1 
ATOM   14065 N N   . ARG D 1 428 ? 3.580   109.213 10.546  1.00 38.23  ? 428 ARG D N   1 
ATOM   14066 C CA  A ARG D 1 428 ? 3.245   110.546 11.032  0.50 41.73  ? 428 ARG D CA  1 
ATOM   14067 C CA  B ARG D 1 428 ? 3.210   110.540 11.000  0.50 40.10  ? 428 ARG D CA  1 
ATOM   14068 C C   . ARG D 1 428 ? 4.066   111.593 10.280  1.00 39.27  ? 428 ARG D C   1 
ATOM   14069 O O   . ARG D 1 428 ? 3.547   112.618 9.853   1.00 40.46  ? 428 ARG D O   1 
ATOM   14070 C CB  A ARG D 1 428 ? 3.487   110.711 12.542  0.50 45.63  ? 428 ARG D CB  1 
ATOM   14071 C CB  B ARG D 1 428 ? 3.222   110.545 12.535  0.50 40.97  ? 428 ARG D CB  1 
ATOM   14072 C CG  A ARG D 1 428 ? 3.248   112.104 13.127  0.50 47.95  ? 428 ARG D CG  1 
ATOM   14073 C CG  B ARG D 1 428 ? 2.736   111.845 13.159  0.50 41.84  ? 428 ARG D CG  1 
ATOM   14074 C CD  A ARG D 1 428 ? 4.141   112.516 14.318  0.50 47.97  ? 428 ARG D CD  1 
ATOM   14075 C CD  B ARG D 1 428 ? 3.160   112.023 14.609  0.50 40.68  ? 428 ARG D CD  1 
ATOM   14076 N NE  A ARG D 1 428 ? 5.541   112.773 13.950  0.50 48.23  ? 428 ARG D NE  1 
ATOM   14077 N NE  B ARG D 1 428 ? 2.184   111.489 15.560  0.50 39.91  ? 428 ARG D NE  1 
ATOM   14078 C CZ  A ARG D 1 428 ? 5.961   113.775 13.186  0.50 50.76  ? 428 ARG D CZ  1 
ATOM   14079 C CZ  B ARG D 1 428 ? 1.370   112.267 16.259  0.50 36.52  ? 428 ARG D CZ  1 
ATOM   14080 N NH1 A ARG D 1 428 ? 5.133   114.740 12.827  0.50 50.03  ? 428 ARG D NH1 1 
ATOM   14081 N NH1 B ARG D 1 428 ? 0.731   111.760 17.290  0.50 35.46  ? 428 ARG D NH1 1 
ATOM   14082 N NH2 A ARG D 1 428 ? 7.219   113.813 12.793  0.50 51.27  ? 428 ARG D NH2 1 
ATOM   14083 N NH2 B ARG D 1 428 ? 1.265   113.553 15.972  0.50 32.56  ? 428 ARG D NH2 1 
ATOM   14084 N N   . TRP D 1 429 ? 5.372   111.353 10.151  1.00 38.68  ? 429 TRP D N   1 
ATOM   14085 C CA  . TRP D 1 429 ? 6.267   112.240 9.416   1.00 39.37  ? 429 TRP D CA  1 
ATOM   14086 C C   . TRP D 1 429 ? 5.837   112.330 7.948   1.00 44.82  ? 429 TRP D C   1 
ATOM   14087 O O   . TRP D 1 429 ? 5.775   113.427 7.381   1.00 41.88  ? 429 TRP D O   1 
ATOM   14088 C CB  . TRP D 1 429 ? 7.723   111.742 9.526   1.00 39.46  ? 429 TRP D CB  1 
ATOM   14089 C CG  . TRP D 1 429 ? 8.709   112.535 8.705   1.00 39.33  ? 429 TRP D CG  1 
ATOM   14090 C CD1 . TRP D 1 429 ? 9.266   113.735 9.048   1.00 38.60  ? 429 TRP D CD1 1 
ATOM   14091 C CD2 . TRP D 1 429 ? 9.273   112.196 7.419   1.00 37.02  ? 429 TRP D CD2 1 
ATOM   14092 N NE1 . TRP D 1 429 ? 10.102  114.182 8.060   1.00 34.63  ? 429 TRP D NE1 1 
ATOM   14093 C CE2 . TRP D 1 429 ? 10.139  113.252 7.058   1.00 37.31  ? 429 TRP D CE2 1 
ATOM   14094 C CE3 . TRP D 1 429 ? 9.144   111.116 6.543   1.00 37.63  ? 429 TRP D CE3 1 
ATOM   14095 C CZ2 . TRP D 1 429 ? 10.863  113.245 5.868   1.00 37.79  ? 429 TRP D CZ2 1 
ATOM   14096 C CZ3 . TRP D 1 429 ? 9.857   111.115 5.364   1.00 35.75  ? 429 TRP D CZ3 1 
ATOM   14097 C CH2 . TRP D 1 429 ? 10.707  112.162 5.036   1.00 36.86  ? 429 TRP D CH2 1 
ATOM   14098 N N   . VAL D 1 430 ? 5.547   111.163 7.338   1.00 43.25  ? 430 VAL D N   1 
ATOM   14099 C CA  . VAL D 1 430 ? 5.196   111.094 5.929   1.00 38.87  ? 430 VAL D CA  1 
ATOM   14100 C C   . VAL D 1 430 ? 3.968   111.970 5.713   1.00 39.34  ? 430 VAL D C   1 
ATOM   14101 O O   . VAL D 1 430 ? 3.977   112.847 4.846   1.00 35.35  ? 430 VAL D O   1 
ATOM   14102 C CB  . VAL D 1 430 ? 4.966   109.648 5.445   1.00 36.75  ? 430 VAL D CB  1 
ATOM   14103 C CG1 . VAL D 1 430 ? 4.165   109.574 4.154   1.00 35.66  ? 430 VAL D CG1 1 
ATOM   14104 C CG2 . VAL D 1 430 ? 6.278   108.895 5.295   1.00 38.29  ? 430 VAL D CG2 1 
ATOM   14105 N N   . LYS D 1 431 ? 2.931   111.753 6.534   1.00 38.71  ? 431 LYS D N   1 
ATOM   14106 C CA  . LYS D 1 431 ? 1.673   112.472 6.353   1.00 43.65  ? 431 LYS D CA  1 
ATOM   14107 C C   . LYS D 1 431 ? 1.905   113.979 6.463   1.00 45.47  ? 431 LYS D C   1 
ATOM   14108 O O   . LYS D 1 431 ? 1.275   114.768 5.769   1.00 52.65  ? 431 LYS D O   1 
ATOM   14109 C CB  . LYS D 1 431 ? 0.558   112.028 7.309   1.00 44.92  ? 431 LYS D CB  1 
ATOM   14110 C CG  . LYS D 1 431 ? -0.056  110.679 6.977   1.00 47.14  ? 431 LYS D CG  1 
ATOM   14111 C CD  . LYS D 1 431 ? -1.435  110.431 7.571   1.00 52.48  ? 431 LYS D CD  1 
ATOM   14112 C CE  . LYS D 1 431 ? -1.444  110.301 9.068   1.00 58.42  ? 431 LYS D CE  1 
ATOM   14113 N NZ  . LYS D 1 431 ? -2.814  110.237 9.601   1.00 58.41  ? 431 LYS D NZ  1 
ATOM   14114 N N   . GLU D 1 432 ? 2.848   114.388 7.300   1.00 46.42  ? 432 GLU D N   1 
ATOM   14115 C CA  . GLU D 1 432 ? 3.051   115.800 7.530   1.00 48.91  ? 432 GLU D CA  1 
ATOM   14116 C C   . GLU D 1 432 ? 3.772   116.444 6.351   1.00 52.65  ? 432 GLU D C   1 
ATOM   14117 O O   . GLU D 1 432 ? 3.469   117.590 6.044   1.00 60.94  ? 432 GLU D O   1 
ATOM   14118 C CB  . GLU D 1 432 ? 3.786   115.935 8.854   1.00 50.76  ? 432 GLU D CB  1 
ATOM   14119 C CG  . GLU D 1 432 ? 3.919   117.367 9.351   1.00 58.86  ? 432 GLU D CG  1 
ATOM   14120 C CD  . GLU D 1 432 ? 5.131   117.409 10.262  1.00 65.66  ? 432 GLU D CD  1 
ATOM   14121 O OE1 . GLU D 1 432 ? 6.024   118.258 10.038  1.00 61.05  ? 432 GLU D OE1 1 
ATOM   14122 O OE2 . GLU D 1 432 ? 5.198   116.518 11.153  1.00 70.38  ? 432 GLU D OE2 1 
ATOM   14123 N N   . VAL D 1 433 ? 4.703   115.726 5.696   1.00 51.86  ? 433 VAL D N   1 
ATOM   14124 C CA  . VAL D 1 433 ? 5.634   116.362 4.769   1.00 45.73  ? 433 VAL D CA  1 
ATOM   14125 C C   . VAL D 1 433 ? 5.361   115.966 3.320   1.00 45.27  ? 433 VAL D C   1 
ATOM   14126 O O   . VAL D 1 433 ? 6.007   116.523 2.433   1.00 51.40  ? 433 VAL D O   1 
ATOM   14127 C CB  . VAL D 1 433 ? 7.123   116.079 5.053   1.00 48.64  ? 433 VAL D CB  1 
ATOM   14128 C CG1 . VAL D 1 433 ? 7.541   116.448 6.471   1.00 48.76  ? 433 VAL D CG1 1 
ATOM   14129 C CG2 . VAL D 1 433 ? 7.490   114.636 4.718   1.00 50.06  ? 433 VAL D CG2 1 
ATOM   14130 N N   . ALA D 1 434 ? 4.469   114.996 3.072   1.00 43.23  ? 434 ALA D N   1 
ATOM   14131 C CA  . ALA D 1 434 ? 4.348   114.376 1.756   1.00 42.23  ? 434 ALA D CA  1 
ATOM   14132 C C   . ALA D 1 434 ? 3.998   115.394 0.671   1.00 47.49  ? 434 ALA D C   1 
ATOM   14133 O O   . ALA D 1 434 ? 4.486   115.272 -0.449  1.00 53.35  ? 434 ALA D O   1 
ATOM   14134 C CB  . ALA D 1 434 ? 3.313   113.274 1.766   1.00 40.54  ? 434 ALA D CB  1 
ATOM   14135 N N   . GLU D 1 435 ? 3.136   116.370 0.994   1.00 51.24  ? 435 GLU D N   1 
ATOM   14136 C CA  . GLU D 1 435 ? 2.688   117.374 0.034   1.00 52.99  ? 435 GLU D CA  1 
ATOM   14137 C C   . GLU D 1 435 ? 3.847   118.273 -0.407  1.00 53.66  ? 435 GLU D C   1 
ATOM   14138 O O   . GLU D 1 435 ? 3.865   118.683 -1.564  1.00 54.29  ? 435 GLU D O   1 
ATOM   14139 C CB  . GLU D 1 435 ? 1.540   118.228 0.581   1.00 52.30  ? 435 GLU D CB  1 
ATOM   14140 C CG  . GLU D 1 435 ? 0.176   117.556 0.455   1.00 53.32  ? 435 GLU D CG  1 
ATOM   14141 C CD  . GLU D 1 435 ? -0.336  117.491 -0.975  1.00 60.81  ? 435 GLU D CD  1 
ATOM   14142 O OE1 . GLU D 1 435 ? 0.029   118.393 -1.772  1.00 58.35  ? 435 GLU D OE1 1 
ATOM   14143 O OE2 . GLU D 1 435 ? -1.065  116.518 -1.306  1.00 61.02  ? 435 GLU D OE2 1 
ATOM   14144 N N   . SER D 1 436 ? 4.806   118.543 0.502   1.00 52.89  ? 436 SER D N   1 
ATOM   14145 C CA  . SER D 1 436 ? 5.905   119.473 0.262   1.00 52.50  ? 436 SER D CA  1 
ATOM   14146 C C   . SER D 1 436 ? 7.062   118.827 -0.506  1.00 50.66  ? 436 SER D C   1 
ATOM   14147 O O   . SER D 1 436 ? 7.996   119.506 -0.912  1.00 55.92  ? 436 SER D O   1 
ATOM   14148 C CB  . SER D 1 436 ? 6.421   120.044 1.564   1.00 51.99  ? 436 SER D CB  1 
ATOM   14149 O OG  . SER D 1 436 ? 7.411   119.191 2.128   1.00 52.88  ? 436 SER D OG  1 
ATOM   14150 N N   . LEU D 1 437 ? 7.055   117.505 -0.655  1.00 53.14  ? 437 LEU D N   1 
ATOM   14151 C CA  . LEU D 1 437 ? 8.183   116.829 -1.271  1.00 50.80  ? 437 LEU D CA  1 
ATOM   14152 C C   . LEU D 1 437 ? 8.098   117.021 -2.778  1.00 47.49  ? 437 LEU D C   1 
ATOM   14153 O O   . LEU D 1 437 ? 7.002   117.096 -3.326  1.00 44.70  ? 437 LEU D O   1 
ATOM   14154 C CB  . LEU D 1 437 ? 8.195   115.339 -0.925  1.00 51.99  ? 437 LEU D CB  1 
ATOM   14155 C CG  . LEU D 1 437 ? 8.526   114.955 0.524   1.00 50.05  ? 437 LEU D CG  1 
ATOM   14156 C CD1 . LEU D 1 437 ? 8.315   113.459 0.697   1.00 46.60  ? 437 LEU D CD1 1 
ATOM   14157 C CD2 . LEU D 1 437 ? 9.931   115.345 0.928   1.00 45.66  ? 437 LEU D CD2 1 
ATOM   14158 N N   . PRO D 1 438 ? 9.252   117.065 -3.479  1.00 44.41  ? 438 PRO D N   1 
ATOM   14159 C CA  . PRO D 1 438 ? 9.278   116.980 -4.938  1.00 44.33  ? 438 PRO D CA  1 
ATOM   14160 C C   . PRO D 1 438 ? 8.829   115.603 -5.425  1.00 44.94  ? 438 PRO D C   1 
ATOM   14161 O O   . PRO D 1 438 ? 8.889   114.620 -4.694  1.00 47.11  ? 438 PRO D O   1 
ATOM   14162 C CB  . PRO D 1 438 ? 10.755  117.241 -5.306  1.00 45.69  ? 438 PRO D CB  1 
ATOM   14163 C CG  . PRO D 1 438 ? 11.546  116.878 -4.054  1.00 44.77  ? 438 PRO D CG  1 
ATOM   14164 C CD  . PRO D 1 438 ? 10.600  117.163 -2.892  1.00 45.98  ? 438 PRO D CD  1 
ATOM   14165 N N   . VAL D 1 439 ? 8.399   115.537 -6.679  1.00 41.61  ? 439 VAL D N   1 
ATOM   14166 C CA  . VAL D 1 439 ? 8.149   114.266 -7.330  1.00 43.51  ? 439 VAL D CA  1 
ATOM   14167 C C   . VAL D 1 439 ? 9.443   113.784 -7.997  1.00 49.07  ? 439 VAL D C   1 
ATOM   14168 O O   . VAL D 1 439 ? 10.381  114.558 -8.231  1.00 49.03  ? 439 VAL D O   1 
ATOM   14169 C CB  . VAL D 1 439 ? 6.967   114.495 -8.297  1.00 43.03  ? 439 VAL D CB  1 
ATOM   14170 C CG1 . VAL D 1 439 ? 6.632   113.275 -9.147  1.00 41.78  ? 439 VAL D CG1 1 
ATOM   14171 C CG2 . VAL D 1 439 ? 5.729   114.980 -7.538  1.00 40.24  ? 439 VAL D CG2 1 
ATOM   14172 N N   . ALA D 1 440 ? 9.494   112.476 -8.284  1.00 55.49  ? 440 ALA D N   1 
ATOM   14173 C CA  . ALA D 1 440 ? 10.731  111.791 -8.635  1.00 56.58  ? 440 ALA D CA  1 
ATOM   14174 C C   . ALA D 1 440 ? 11.072  111.920 -10.132 1.00 48.37  ? 440 ALA D C   1 
ATOM   14175 O O   . ALA D 1 440 ? 10.147  112.029 -10.943 1.00 44.91  ? 440 ALA D O   1 
ATOM   14176 C CB  . ALA D 1 440 ? 10.621  110.344 -8.195  1.00 52.17  ? 440 ALA D CB  1 
ATOM   14177 N N   . MET E 1 1   ? 49.161  33.474  25.720  1.00 41.53  ? 1   MET E N   1 
ATOM   14178 C CA  . MET E 1 1   ? 50.017  34.672  25.899  1.00 39.59  ? 1   MET E CA  1 
ATOM   14179 C C   . MET E 1 1   ? 51.223  34.324  26.781  1.00 48.07  ? 1   MET E C   1 
ATOM   14180 O O   . MET E 1 1   ? 51.081  33.802  27.889  1.00 45.75  ? 1   MET E O   1 
ATOM   14181 C CB  . MET E 1 1   ? 49.149  35.778  26.485  1.00 37.00  ? 1   MET E CB  1 
ATOM   14182 C CG  . MET E 1 1   ? 49.698  37.140  26.267  1.00 38.68  ? 1   MET E CG  1 
ATOM   14183 S SD  . MET E 1 1   ? 48.738  38.242  27.316  1.00 43.96  ? 1   MET E SD  1 
ATOM   14184 C CE  . MET E 1 1   ? 49.390  39.740  26.569  1.00 46.31  ? 1   MET E CE  1 
ATOM   14185 N N   . LYS E 1 2   ? 52.436  34.574  26.270  1.00 56.74  ? 2   LYS E N   1 
ATOM   14186 C CA  . LYS E 1 2   ? 53.637  34.211  27.003  1.00 57.86  ? 2   LYS E CA  1 
ATOM   14187 C C   . LYS E 1 2   ? 53.641  34.919  28.350  1.00 44.75  ? 2   LYS E C   1 
ATOM   14188 O O   . LYS E 1 2   ? 54.004  34.305  29.336  1.00 45.65  ? 2   LYS E O   1 
ATOM   14189 C CB  . LYS E 1 2   ? 54.963  34.561  26.320  1.00 76.38  ? 2   LYS E CB  1 
ATOM   14190 C CG  . LYS E 1 2   ? 55.228  33.811  25.033  1.00 96.97  ? 2   LYS E CG  1 
ATOM   14191 C CD  . LYS E 1 2   ? 55.527  32.337  25.254  1.00 108.38 ? 2   LYS E CD  1 
ATOM   14192 C CE  . LYS E 1 2   ? 55.305  31.552  24.006  1.00 114.08 ? 2   LYS E CE  1 
ATOM   14193 N NZ  . LYS E 1 2   ? 55.533  30.128  24.255  1.00 119.84 ? 2   LYS E NZ  1 
ATOM   14194 N N   . LEU E 1 3   ? 53.260  36.201  28.373  1.00 38.71  ? 3   LEU E N   1 
ATOM   14195 C CA  . LEU E 1 3   ? 53.226  36.996  29.595  1.00 37.43  ? 3   LEU E CA  1 
ATOM   14196 C C   . LEU E 1 3   ? 52.471  36.237  30.696  1.00 34.92  ? 3   LEU E C   1 
ATOM   14197 O O   . LEU E 1 3   ? 52.938  36.133  31.816  1.00 30.11  ? 3   LEU E O   1 
ATOM   14198 C CB  . LEU E 1 3   ? 52.617  38.365  29.281  1.00 34.08  ? 3   LEU E CB  1 
ATOM   14199 C CG  . LEU E 1 3   ? 52.318  39.299  30.460  1.00 34.11  ? 3   LEU E CG  1 
ATOM   14200 C CD1 . LEU E 1 3   ? 53.518  39.665  31.322  1.00 31.19  ? 3   LEU E CD1 1 
ATOM   14201 C CD2 . LEU E 1 3   ? 51.697  40.588  29.933  1.00 34.43  ? 3   LEU E CD2 1 
ATOM   14202 N N   . LYS E 1 4   ? 51.339  35.624  30.364  1.00 37.94  ? 4   LYS E N   1 
ATOM   14203 C CA  . LYS E 1 4   ? 50.569  34.927  31.377  1.00 43.79  ? 4   LYS E CA  1 
ATOM   14204 C C   . LYS E 1 4   ? 51.316  33.668  31.831  1.00 45.78  ? 4   LYS E C   1 
ATOM   14205 O O   . LYS E 1 4   ? 51.546  33.504  33.024  1.00 46.08  ? 4   LYS E O   1 
ATOM   14206 C CB  . LYS E 1 4   ? 49.126  34.682  30.924  1.00 41.88  ? 4   LYS E CB  1 
ATOM   14207 C CG  . LYS E 1 4   ? 48.295  33.974  31.987  1.00 40.90  ? 4   LYS E CG  1 
ATOM   14208 C CD  . LYS E 1 4   ? 46.783  34.051  31.842  1.00 43.85  ? 4   LYS E CD  1 
ATOM   14209 C CE  . LYS E 1 4   ? 46.090  33.116  32.816  1.00 52.55  ? 4   LYS E CE  1 
ATOM   14210 N NZ  . LYS E 1 4   ? 44.805  33.611  33.341  1.00 56.47  ? 4   LYS E NZ  1 
ATOM   14211 N N   . GLU E 1 5   ? 51.679  32.785  30.889  1.00 45.18  ? 5   GLU E N   1 
ATOM   14212 C CA  . GLU E 1 5   ? 52.412  31.564  31.198  1.00 43.98  ? 5   GLU E CA  1 
ATOM   14213 C C   . GLU E 1 5   ? 53.617  31.858  32.101  1.00 41.08  ? 5   GLU E C   1 
ATOM   14214 O O   . GLU E 1 5   ? 53.993  31.049  32.953  1.00 40.70  ? 5   GLU E O   1 
ATOM   14215 C CB  . GLU E 1 5   ? 52.843  30.938  29.874  1.00 48.43  ? 5   GLU E CB  1 
ATOM   14216 C CG  . GLU E 1 5   ? 51.677  30.322  29.102  1.00 60.15  ? 5   GLU E CG  1 
ATOM   14217 C CD  . GLU E 1 5   ? 51.936  29.982  27.645  1.00 60.57  ? 5   GLU E CD  1 
ATOM   14218 O OE1 . GLU E 1 5   ? 51.064  29.295  27.107  1.00 59.83  ? 5   GLU E OE1 1 
ATOM   14219 O OE2 . GLU E 1 5   ? 52.956  30.390  27.050  1.00 66.26  ? 5   GLU E OE2 1 
ATOM   14220 N N   . ARG E 1 6   ? 54.213  33.036  31.900  1.00 37.40  ? 6   ARG E N   1 
ATOM   14221 C CA  . ARG E 1 6   ? 55.419  33.451  32.586  1.00 37.77  ? 6   ARG E CA  1 
ATOM   14222 C C   . ARG E 1 6   ? 55.082  33.844  34.027  1.00 34.54  ? 6   ARG E C   1 
ATOM   14223 O O   . ARG E 1 6   ? 55.727  33.378  34.969  1.00 31.64  ? 6   ARG E O   1 
ATOM   14224 C CB  . ARG E 1 6   ? 55.979  34.575  31.710  1.00 40.70  ? 6   ARG E CB  1 
ATOM   14225 C CG  . ARG E 1 6   ? 57.471  34.818  31.808  1.00 45.56  ? 6   ARG E CG  1 
ATOM   14226 C CD  . ARG E 1 6   ? 58.277  33.593  31.415  1.00 46.35  ? 6   ARG E CD  1 
ATOM   14227 N NE  . ARG E 1 6   ? 59.431  33.656  32.320  1.00 48.31  ? 6   ARG E NE  1 
ATOM   14228 C CZ  . ARG E 1 6   ? 59.689  32.818  33.302  1.00 43.72  ? 6   ARG E CZ  1 
ATOM   14229 N NH1 . ARG E 1 6   ? 59.043  31.669  33.334  1.00 46.24  ? 6   ARG E NH1 1 
ATOM   14230 N NH2 . ARG E 1 6   ? 60.608  33.115  34.211  1.00 39.38  ? 6   ARG E NH2 1 
ATOM   14231 N N   . LEU E 1 7   ? 54.051  34.686  34.175  1.00 32.81  ? 7   LEU E N   1 
ATOM   14232 C CA  . LEU E 1 7   ? 53.549  35.108  35.470  1.00 30.41  ? 7   LEU E CA  1 
ATOM   14233 C C   . LEU E 1 7   ? 53.032  33.899  36.239  1.00 31.04  ? 7   LEU E C   1 
ATOM   14234 O O   . LEU E 1 7   ? 53.186  33.839  37.464  1.00 35.58  ? 7   LEU E O   1 
ATOM   14235 C CB  . LEU E 1 7   ? 52.482  36.186  35.342  1.00 30.03  ? 7   LEU E CB  1 
ATOM   14236 C CG  . LEU E 1 7   ? 52.954  37.559  34.855  1.00 31.26  ? 7   LEU E CG  1 
ATOM   14237 C CD1 . LEU E 1 7   ? 51.779  38.509  34.781  1.00 33.09  ? 7   LEU E CD1 1 
ATOM   14238 C CD2 . LEU E 1 7   ? 53.984  38.198  35.733  1.00 33.92  ? 7   LEU E CD2 1 
ATOM   14239 N N   . ALA E 1 8   ? 52.494  32.901  35.533  1.00 32.18  ? 8   ALA E N   1 
ATOM   14240 C CA  . ALA E 1 8   ? 52.110  31.654  36.193  1.00 36.65  ? 8   ALA E CA  1 
ATOM   14241 C C   . ALA E 1 8   ? 53.314  31.028  36.901  1.00 38.14  ? 8   ALA E C   1 
ATOM   14242 O O   . ALA E 1 8   ? 53.174  30.615  38.040  1.00 40.67  ? 8   ALA E O   1 
ATOM   14243 C CB  . ALA E 1 8   ? 51.459  30.675  35.232  1.00 33.97  ? 8   ALA E CB  1 
ATOM   14244 N N   . GLU E 1 9   ? 54.500  31.000  36.265  1.00 45.96  ? 9   GLU E N   1 
ATOM   14245 C CA  . GLU E 1 9   ? 55.689  30.425  36.890  1.00 43.26  ? 9   GLU E CA  1 
ATOM   14246 C C   . GLU E 1 9   ? 56.252  31.368  37.950  1.00 37.14  ? 9   GLU E C   1 
ATOM   14247 O O   . GLU E 1 9   ? 56.597  30.912  39.033  1.00 39.96  ? 9   GLU E O   1 
ATOM   14248 C CB  . GLU E 1 9   ? 56.746  30.018  35.870  1.00 49.56  ? 9   GLU E CB  1 
ATOM   14249 C CG  . GLU E 1 9   ? 56.354  28.787  35.049  1.00 62.07  ? 9   GLU E CG  1 
ATOM   14250 C CD  . GLU E 1 9   ? 56.939  28.697  33.627  1.00 74.87  ? 9   GLU E CD  1 
ATOM   14251 O OE1 . GLU E 1 9   ? 56.419  27.941  32.755  1.00 70.09  ? 9   GLU E OE1 1 
ATOM   14252 O OE2 . GLU E 1 9   ? 57.938  29.403  33.369  1.00 68.41  ? 9   GLU E OE2 1 
ATOM   14253 N N   . LEU E 1 10  ? 56.268  32.680  37.694  1.00 32.59  ? 10  LEU E N   1 
ATOM   14254 C CA  . LEU E 1 10  ? 57.033  33.589  38.541  1.00 33.50  ? 10  LEU E CA  1 
ATOM   14255 C C   . LEU E 1 10  ? 56.317  33.943  39.839  1.00 34.99  ? 10  LEU E C   1 
ATOM   14256 O O   . LEU E 1 10  ? 56.978  34.173  40.847  1.00 41.11  ? 10  LEU E O   1 
ATOM   14257 C CB  . LEU E 1 10  ? 57.412  34.889  37.837  1.00 32.42  ? 10  LEU E CB  1 
ATOM   14258 C CG  . LEU E 1 10  ? 58.520  34.792  36.786  1.00 33.85  ? 10  LEU E CG  1 
ATOM   14259 C CD1 . LEU E 1 10  ? 58.686  36.135  36.081  1.00 34.52  ? 10  LEU E CD1 1 
ATOM   14260 C CD2 . LEU E 1 10  ? 59.839  34.340  37.369  1.00 32.18  ? 10  LEU E CD2 1 
ATOM   14261 N N   . ILE E 1 11  ? 54.997  34.116  39.793  1.00 36.14  ? 11  ILE E N   1 
ATOM   14262 C CA  . ILE E 1 11  ? 54.278  34.761  40.886  1.00 35.47  ? 11  ILE E CA  1 
ATOM   14263 C C   . ILE E 1 11  ? 54.230  33.850  42.125  1.00 33.63  ? 11  ILE E C   1 
ATOM   14264 O O   . ILE E 1 11  ? 54.447  34.316  43.252  1.00 27.75  ? 11  ILE E O   1 
ATOM   14265 C CB  . ILE E 1 11  ? 52.898  35.241  40.381  1.00 36.75  ? 11  ILE E CB  1 
ATOM   14266 C CG1 . ILE E 1 11  ? 53.048  36.571  39.625  1.00 33.29  ? 11  ILE E CG1 1 
ATOM   14267 C CG2 . ILE E 1 11  ? 51.870  35.345  41.515  1.00 36.83  ? 11  ILE E CG2 1 
ATOM   14268 C CD1 . ILE E 1 11  ? 51.744  37.132  39.091  1.00 34.91  ? 11  ILE E CD1 1 
ATOM   14269 N N   . PRO E 1 12  ? 53.953  32.529  41.987  1.00 35.46  ? 12  PRO E N   1 
ATOM   14270 C CA  . PRO E 1 12  ? 54.162  31.592  43.097  1.00 37.65  ? 12  PRO E CA  1 
ATOM   14271 C C   . PRO E 1 12  ? 55.550  31.657  43.740  1.00 40.80  ? 12  PRO E C   1 
ATOM   14272 O O   . PRO E 1 12  ? 55.673  31.609  44.961  1.00 48.84  ? 12  PRO E O   1 
ATOM   14273 C CB  . PRO E 1 12  ? 53.858  30.220  42.453  1.00 35.68  ? 12  PRO E CB  1 
ATOM   14274 C CG  . PRO E 1 12  ? 52.848  30.540  41.377  1.00 34.62  ? 12  PRO E CG  1 
ATOM   14275 C CD  . PRO E 1 12  ? 53.339  31.876  40.817  1.00 34.71  ? 12  PRO E CD  1 
ATOM   14276 N N   . GLN E 1 13  ? 56.598  31.760  42.926  1.00 41.52  ? 13  GLN E N   1 
ATOM   14277 C CA  . GLN E 1 13  ? 57.939  31.941  43.455  1.00 44.98  ? 13  GLN E CA  1 
ATOM   14278 C C   . GLN E 1 13  ? 57.995  33.226  44.274  1.00 38.58  ? 13  GLN E C   1 
ATOM   14279 O O   . GLN E 1 13  ? 58.507  33.213  45.382  1.00 41.41  ? 13  GLN E O   1 
ATOM   14280 C CB  . GLN E 1 13  ? 59.057  32.003  42.407  1.00 50.40  ? 13  GLN E CB  1 
ATOM   14281 C CG  . GLN E 1 13  ? 59.248  30.719  41.598  1.00 56.60  ? 13  GLN E CG  1 
ATOM   14282 C CD  . GLN E 1 13  ? 60.283  30.860  40.498  1.00 55.38  ? 13  GLN E CD  1 
ATOM   14283 O OE1 . GLN E 1 13  ? 61.217  31.670  40.567  1.00 53.38  ? 13  GLN E OE1 1 
ATOM   14284 N NE2 . GLN E 1 13  ? 60.109  30.073  39.451  1.00 53.73  ? 13  GLN E NE2 1 
ATOM   14285 N N   . TRP E 1 14  ? 57.491  34.332  43.724  1.00 36.21  ? 14  TRP E N   1 
ATOM   14286 C CA  . TRP E 1 14  ? 57.569  35.618  44.400  1.00 35.90  ? 14  TRP E CA  1 
ATOM   14287 C C   . TRP E 1 14  ? 56.725  35.618  45.660  1.00 34.71  ? 14  TRP E C   1 
ATOM   14288 O O   . TRP E 1 14  ? 56.998  36.374  46.579  1.00 35.21  ? 14  TRP E O   1 
ATOM   14289 C CB  . TRP E 1 14  ? 57.084  36.761  43.501  1.00 37.26  ? 14  TRP E CB  1 
ATOM   14290 C CG  . TRP E 1 14  ? 58.009  37.037  42.355  1.00 37.60  ? 14  TRP E CG  1 
ATOM   14291 C CD1 . TRP E 1 14  ? 59.349  36.807  42.319  1.00 35.08  ? 14  TRP E CD1 1 
ATOM   14292 C CD2 . TRP E 1 14  ? 57.655  37.628  41.092  1.00 37.26  ? 14  TRP E CD2 1 
ATOM   14293 N NE1 . TRP E 1 14  ? 59.849  37.178  41.111  1.00 34.15  ? 14  TRP E NE1 1 
ATOM   14294 C CE2 . TRP E 1 14  ? 58.847  37.710  40.344  1.00 38.79  ? 14  TRP E CE2 1 
ATOM   14295 C CE3 . TRP E 1 14  ? 56.464  38.094  40.533  1.00 33.44  ? 14  TRP E CE3 1 
ATOM   14296 C CZ2 . TRP E 1 14  ? 58.880  38.235  39.054  1.00 36.35  ? 14  TRP E CZ2 1 
ATOM   14297 C CZ3 . TRP E 1 14  ? 56.502  38.626  39.271  1.00 34.91  ? 14  TRP E CZ3 1 
ATOM   14298 C CH2 . TRP E 1 14  ? 57.692  38.701  38.548  1.00 37.16  ? 14  TRP E CH2 1 
ATOM   14299 N N   . ARG E 1 15  ? 55.651  34.838  45.641  1.00 37.57  ? 15  ARG E N   1 
ATOM   14300 C CA  . ARG E 1 15  ? 54.739  34.809  46.761  1.00 40.96  ? 15  ARG E CA  1 
ATOM   14301 C C   . ARG E 1 15  ? 55.459  34.122  47.917  1.00 38.49  ? 15  ARG E C   1 
ATOM   14302 O O   . ARG E 1 15  ? 55.485  34.652  49.032  1.00 39.26  ? 15  ARG E O   1 
ATOM   14303 C CB  . ARG E 1 15  ? 53.435  34.208  46.233  1.00 45.34  ? 15  ARG E CB  1 
ATOM   14304 C CG  . ARG E 1 15  ? 52.334  34.005  47.255  1.00 48.29  ? 15  ARG E CG  1 
ATOM   14305 C CD  . ARG E 1 15  ? 51.205  33.243  46.612  1.00 55.17  ? 15  ARG E CD  1 
ATOM   14306 N NE  . ARG E 1 15  ? 50.642  32.285  47.570  1.00 72.16  ? 15  ARG E NE  1 
ATOM   14307 C CZ  . ARG E 1 15  ? 50.589  30.955  47.440  1.00 84.61  ? 15  ARG E CZ  1 
ATOM   14308 N NH1 . ARG E 1 15  ? 51.087  30.361  46.364  1.00 89.48  ? 15  ARG E NH1 1 
ATOM   14309 N NH2 . ARG E 1 15  ? 50.026  30.222  48.392  1.00 79.54  ? 15  ARG E NH2 1 
ATOM   14310 N N   . ALA E 1 16  ? 56.115  32.992  47.620  1.00 36.98  ? 16  ALA E N   1 
ATOM   14311 C CA  . ALA E 1 16  ? 56.842  32.230  48.632  1.00 35.98  ? 16  ALA E CA  1 
ATOM   14312 C C   . ALA E 1 16  ? 58.043  33.032  49.157  1.00 35.46  ? 16  ALA E C   1 
ATOM   14313 O O   . ALA E 1 16  ? 58.280  33.093  50.358  1.00 36.11  ? 16  ALA E O   1 
ATOM   14314 C CB  . ALA E 1 16  ? 57.230  30.866  48.080  1.00 35.04  ? 16  ALA E CB  1 
ATOM   14315 N N   . GLU E 1 17  ? 58.765  33.706  48.263  1.00 39.02  ? 17  GLU E N   1 
ATOM   14316 C CA  . GLU E 1 17  ? 59.892  34.544  48.640  1.00 44.95  ? 17  GLU E CA  1 
ATOM   14317 C C   . GLU E 1 17  ? 59.462  35.627  49.626  1.00 40.36  ? 17  GLU E C   1 
ATOM   14318 O O   . GLU E 1 17  ? 60.171  35.864  50.600  1.00 35.53  ? 17  GLU E O   1 
ATOM   14319 C CB  . GLU E 1 17  ? 60.608  35.162  47.430  1.00 54.72  ? 17  GLU E CB  1 
ATOM   14320 C CG  . GLU E 1 17  ? 62.033  34.654  47.200  1.00 68.43  ? 17  GLU E CG  1 
ATOM   14321 C CD  . GLU E 1 17  ? 62.993  34.810  48.394  1.00 94.08  ? 17  GLU E CD  1 
ATOM   14322 O OE1 . GLU E 1 17  ? 62.972  33.973  49.350  1.00 84.14  ? 17  GLU E OE1 1 
ATOM   14323 O OE2 . GLU E 1 17  ? 63.777  35.800  48.386  1.00 107.94 ? 17  GLU E OE2 1 
ATOM   14324 N N   . VAL E 1 18  ? 58.331  36.299  49.347  1.00 43.32  ? 18  VAL E N   1 
ATOM   14325 C CA  . VAL E 1 18  ? 57.841  37.422  50.146  1.00 39.87  ? 18  VAL E CA  1 
ATOM   14326 C C   . VAL E 1 18  ? 57.356  36.944  51.522  1.00 35.68  ? 18  VAL E C   1 
ATOM   14327 O O   . VAL E 1 18  ? 57.542  37.617  52.534  1.00 35.59  ? 18  VAL E O   1 
ATOM   14328 C CB  . VAL E 1 18  ? 56.738  38.170  49.365  1.00 40.26  ? 18  VAL E CB  1 
ATOM   14329 C CG1 . VAL E 1 18  ? 55.855  39.029  50.253  1.00 41.82  ? 18  VAL E CG1 1 
ATOM   14330 C CG2 . VAL E 1 18  ? 57.337  39.032  48.266  1.00 42.61  ? 18  VAL E CG2 1 
ATOM   14331 N N   . ALA E 1 19  ? 56.709  35.781  51.560  1.00 34.80  ? 19  ALA E N   1 
ATOM   14332 C CA  . ALA E 1 19  ? 56.377  35.130  52.815  1.00 34.95  ? 19  ALA E CA  1 
ATOM   14333 C C   . ALA E 1 19  ? 57.631  34.953  53.669  1.00 39.27  ? 19  ALA E C   1 
ATOM   14334 O O   . ALA E 1 19  ? 57.650  35.409  54.809  1.00 44.09  ? 19  ALA E O   1 
ATOM   14335 C CB  . ALA E 1 19  ? 55.680  33.814  52.542  1.00 33.51  ? 19  ALA E CB  1 
ATOM   14336 N N   . GLU E 1 20  ? 58.661  34.309  53.095  1.00 43.12  ? 20  GLU E N   1 
ATOM   14337 C CA  . GLU E 1 20  ? 59.964  34.112  53.720  1.00 44.65  ? 20  GLU E CA  1 
ATOM   14338 C C   . GLU E 1 20  ? 60.581  35.429  54.189  1.00 41.71  ? 20  GLU E C   1 
ATOM   14339 O O   . GLU E 1 20  ? 61.143  35.494  55.271  1.00 42.45  ? 20  GLU E O   1 
ATOM   14340 C CB  . GLU E 1 20  ? 60.949  33.457  52.746  1.00 51.24  ? 20  GLU E CB  1 
ATOM   14341 C CG  . GLU E 1 20  ? 61.214  31.976  52.998  1.00 60.29  ? 20  GLU E CG  1 
ATOM   14342 C CD  . GLU E 1 20  ? 62.035  31.765  54.258  1.00 69.00  ? 20  GLU E CD  1 
ATOM   14343 O OE1 . GLU E 1 20  ? 63.117  32.382  54.401  1.00 73.42  ? 20  GLU E OE1 1 
ATOM   14344 O OE2 . GLU E 1 20  ? 61.562  31.001  55.121  1.00 78.05  ? 20  GLU E OE2 1 
ATOM   14345 N N   . ILE E 1 21  ? 60.535  36.477  53.367  1.00 42.00  ? 21  ILE E N   1 
ATOM   14346 C CA  . ILE E 1 21  ? 61.148  37.742  53.739  1.00 42.93  ? 21  ILE E CA  1 
ATOM   14347 C C   . ILE E 1 21  ? 60.418  38.357  54.936  1.00 46.02  ? 21  ILE E C   1 
ATOM   14348 O O   . ILE E 1 21  ? 61.009  39.116  55.693  1.00 41.41  ? 21  ILE E O   1 
ATOM   14349 C CB  . ILE E 1 21  ? 61.199  38.704  52.535  1.00 45.28  ? 21  ILE E CB  1 
ATOM   14350 C CG1 . ILE E 1 21  ? 62.254  38.224  51.495  1.00 46.82  ? 21  ILE E CG1 1 
ATOM   14351 C CG2 . ILE E 1 21  ? 61.438  40.159  52.974  1.00 41.32  ? 21  ILE E CG2 1 
ATOM   14352 C CD1 . ILE E 1 21  ? 62.236  38.961  50.166  1.00 42.95  ? 21  ILE E CD1 1 
ATOM   14353 N N   . ARG E 1 22  ? 59.119  38.079  55.080  1.00 51.27  ? 22  ARG E N   1 
ATOM   14354 C CA  . ARG E 1 22  ? 58.339  38.694  56.141  1.00 53.37  ? 22  ARG E CA  1 
ATOM   14355 C C   . ARG E 1 22  ? 58.653  37.989  57.452  1.00 51.20  ? 22  ARG E C   1 
ATOM   14356 O O   . ARG E 1 22  ? 58.921  38.647  58.459  1.00 48.48  ? 22  ARG E O   1 
ATOM   14357 C CB  . ARG E 1 22  ? 56.851  38.685  55.784  1.00 55.31  ? 22  ARG E CB  1 
ATOM   14358 C CG  . ARG E 1 22  ? 56.596  39.718  54.695  1.00 61.10  ? 22  ARG E CG  1 
ATOM   14359 C CD  . ARG E 1 22  ? 55.181  39.661  54.169  1.00 64.67  ? 22  ARG E CD  1 
ATOM   14360 N NE  . ARG E 1 22  ? 54.243  40.291  55.099  1.00 62.32  ? 22  ARG E NE  1 
ATOM   14361 C CZ  . ARG E 1 22  ? 52.971  39.986  55.084  1.00 65.57  ? 22  ARG E CZ  1 
ATOM   14362 N NH1 . ARG E 1 22  ? 52.578  39.005  54.288  1.00 68.60  ? 22  ARG E NH1 1 
ATOM   14363 N NH2 . ARG E 1 22  ? 52.120  40.631  55.866  1.00 61.34  ? 22  ARG E NH2 1 
ATOM   14364 N N   . LYS E 1 23  ? 58.647  36.655  57.383  1.00 49.94  ? 23  LYS E N   1 
ATOM   14365 C CA  . LYS E 1 23  ? 58.986  35.797  58.502  1.00 54.49  ? 23  LYS E CA  1 
ATOM   14366 C C   . LYS E 1 23  ? 60.383  36.137  59.024  1.00 53.31  ? 23  LYS E C   1 
ATOM   14367 O O   . LYS E 1 23  ? 60.538  36.430  60.201  1.00 57.51  ? 23  LYS E O   1 
ATOM   14368 C CB  . LYS E 1 23  ? 58.830  34.331  58.081  1.00 58.59  ? 23  LYS E CB  1 
ATOM   14369 C CG  . LYS E 1 23  ? 59.425  33.299  59.038  1.00 69.07  ? 23  LYS E CG  1 
ATOM   14370 C CD  . LYS E 1 23  ? 59.036  31.857  58.722  1.00 73.21  ? 23  LYS E CD  1 
ATOM   14371 C CE  . LYS E 1 23  ? 59.945  30.839  59.328  1.00 77.92  ? 23  LYS E CE  1 
ATOM   14372 N NZ  . LYS E 1 23  ? 59.467  29.484  59.043  1.00 81.12  ? 23  LYS E NZ  1 
ATOM   14373 N N   . LYS E 1 24  ? 61.380  36.159  58.138  1.00 53.81  ? 24  LYS E N   1 
ATOM   14374 C CA  . LYS E 1 24  ? 62.780  36.172  58.533  1.00 52.51  ? 24  LYS E CA  1 
ATOM   14375 C C   . LYS E 1 24  ? 63.317  37.580  58.823  1.00 47.99  ? 24  LYS E C   1 
ATOM   14376 O O   . LYS E 1 24  ? 64.293  37.701  59.560  1.00 41.24  ? 24  LYS E O   1 
ATOM   14377 C CB  . LYS E 1 24  ? 63.590  35.460  57.443  1.00 58.66  ? 24  LYS E CB  1 
ATOM   14378 C CG  . LYS E 1 24  ? 65.093  35.440  57.669  1.00 70.50  ? 24  LYS E CG  1 
ATOM   14379 C CD  . LYS E 1 24  ? 65.823  34.251  57.052  1.00 81.64  ? 24  LYS E CD  1 
ATOM   14380 C CE  . LYS E 1 24  ? 65.990  34.350  55.572  1.00 88.35  ? 24  LYS E CE  1 
ATOM   14381 N NZ  . LYS E 1 24  ? 66.782  33.218  55.094  1.00 90.82  ? 24  LYS E NZ  1 
ATOM   14382 N N   . TYR E 1 25  ? 62.714  38.630  58.242  1.00 45.23  ? 25  TYR E N   1 
ATOM   14383 C CA  . TYR E 1 25  ? 63.253  39.983  58.320  1.00 48.03  ? 25  TYR E CA  1 
ATOM   14384 C C   . TYR E 1 25  ? 62.181  41.038  58.619  1.00 44.38  ? 25  TYR E C   1 
ATOM   14385 O O   . TYR E 1 25  ? 62.476  42.239  58.586  1.00 43.26  ? 25  TYR E O   1 
ATOM   14386 C CB  . TYR E 1 25  ? 63.937  40.365  57.001  1.00 53.06  ? 25  TYR E CB  1 
ATOM   14387 C CG  . TYR E 1 25  ? 65.126  39.494  56.627  1.00 63.21  ? 25  TYR E CG  1 
ATOM   14388 C CD1 . TYR E 1 25  ? 66.289  39.495  57.396  1.00 69.45  ? 25  TYR E CD1 1 
ATOM   14389 C CD2 . TYR E 1 25  ? 65.107  38.701  55.489  1.00 66.78  ? 25  TYR E CD2 1 
ATOM   14390 C CE1 . TYR E 1 25  ? 67.381  38.710  57.066  1.00 66.32  ? 25  TYR E CE1 1 
ATOM   14391 C CE2 . TYR E 1 25  ? 66.195  37.917  55.142  1.00 72.99  ? 25  TYR E CE2 1 
ATOM   14392 C CZ  . TYR E 1 25  ? 67.331  37.921  55.933  1.00 72.81  ? 25  TYR E CZ  1 
ATOM   14393 O OH  . TYR E 1 25  ? 68.392  37.146  55.584  1.00 76.95  ? 25  TYR E OH  1 
ATOM   14394 N N   . GLY E 1 26  ? 60.952  40.607  58.922  1.00 38.43  ? 26  GLY E N   1 
ATOM   14395 C CA  . GLY E 1 26  ? 59.896  41.531  59.291  1.00 39.74  ? 26  GLY E CA  1 
ATOM   14396 C C   . GLY E 1 26  ? 60.325  42.475  60.411  1.00 40.99  ? 26  GLY E C   1 
ATOM   14397 O O   . GLY E 1 26  ? 60.028  43.675  60.367  1.00 36.12  ? 26  GLY E O   1 
ATOM   14398 N N   . ASN E 1 27  ? 61.052  41.922  61.396  1.00 44.14  ? 27  ASN E N   1 
ATOM   14399 C CA  . ASN E 1 27  ? 61.435  42.671  62.589  1.00 47.32  ? 27  ASN E CA  1 
ATOM   14400 C C   . ASN E 1 27  ? 62.634  43.589  62.332  1.00 42.23  ? 27  ASN E C   1 
ATOM   14401 O O   . ASN E 1 27  ? 63.077  44.280  63.239  1.00 38.41  ? 27  ASN E O   1 
ATOM   14402 C CB  . ASN E 1 27  ? 61.725  41.772  63.786  1.00 44.67  ? 27  ASN E CB  1 
ATOM   14403 C CG  . ASN E 1 27  ? 62.815  40.782  63.474  1.00 53.89  ? 27  ASN E CG  1 
ATOM   14404 O OD1 . ASN E 1 27  ? 62.667  39.586  63.740  1.00 60.98  ? 27  ASN E OD1 1 
ATOM   14405 N ND2 . ASN E 1 27  ? 63.888  41.250  62.859  1.00 55.36  ? 27  ASN E ND2 1 
ATOM   14406 N N   . ARG E 1 28  ? 63.140  43.664  61.102  1.00 42.21  ? 28  ARG E N   1 
ATOM   14407 C CA  . ARG E 1 28  ? 64.277  44.536  60.850  1.00 44.17  ? 28  ARG E CA  1 
ATOM   14408 C C   . ARG E 1 28  ? 63.827  45.992  60.735  1.00 38.57  ? 28  ARG E C   1 
ATOM   14409 O O   . ARG E 1 28  ? 62.904  46.304  59.995  1.00 37.01  ? 28  ARG E O   1 
ATOM   14410 C CB  . ARG E 1 28  ? 65.022  44.060  59.600  1.00 50.14  ? 28  ARG E CB  1 
ATOM   14411 C CG  . ARG E 1 28  ? 65.609  42.665  59.767  1.00 54.45  ? 28  ARG E CG  1 
ATOM   14412 C CD  . ARG E 1 28  ? 66.616  42.544  60.914  1.00 53.67  ? 28  ARG E CD  1 
ATOM   14413 N NE  . ARG E 1 28  ? 66.926  41.127  61.129  1.00 51.86  ? 28  ARG E NE  1 
ATOM   14414 C CZ  . ARG E 1 28  ? 68.095  40.580  60.829  1.00 55.38  ? 28  ARG E CZ  1 
ATOM   14415 N NH1 . ARG E 1 28  ? 68.221  39.262  60.833  1.00 54.38  ? 28  ARG E NH1 1 
ATOM   14416 N NH2 . ARG E 1 28  ? 69.116  41.352  60.478  1.00 53.60  ? 28  ARG E NH2 1 
ATOM   14417 N N   . LYS E 1 29  ? 64.506  46.873  61.472  1.00 34.98  ? 29  LYS E N   1 
ATOM   14418 C CA  . LYS E 1 29  ? 64.192  48.291  61.512  1.00 36.32  ? 29  LYS E CA  1 
ATOM   14419 C C   . LYS E 1 29  ? 64.861  49.011  60.353  1.00 40.27  ? 29  LYS E C   1 
ATOM   14420 O O   . LYS E 1 29  ? 66.074  48.864  60.191  1.00 42.74  ? 29  LYS E O   1 
ATOM   14421 C CB  . LYS E 1 29  ? 64.736  48.905  62.803  1.00 33.81  ? 29  LYS E CB  1 
ATOM   14422 C CG  . LYS E 1 29  ? 64.988  50.408  62.794  1.00 34.79  ? 29  LYS E CG  1 
ATOM   14423 C CD  . LYS E 1 29  ? 65.457  50.996  64.132  1.00 34.87  ? 29  LYS E CD  1 
ATOM   14424 C CE  . LYS E 1 29  ? 65.617  52.478  63.994  1.00 34.51  ? 29  LYS E CE  1 
ATOM   14425 N NZ  . LYS E 1 29  ? 65.885  53.176  65.240  1.00 33.66  ? 29  LYS E NZ  1 
ATOM   14426 N N   . THR E 1 30  ? 64.076  49.817  59.606  1.00 37.79  ? 30  THR E N   1 
ATOM   14427 C CA  . THR E 1 30  ? 64.587  50.573  58.464  1.00 36.29  ? 30  THR E CA  1 
ATOM   14428 C C   . THR E 1 30  ? 64.852  52.025  58.861  1.00 31.38  ? 30  THR E C   1 
ATOM   14429 O O   . THR E 1 30  ? 65.731  52.652  58.298  1.00 36.62  ? 30  THR E O   1 
ATOM   14430 C CB  . THR E 1 30  ? 63.640  50.497  57.260  1.00 34.69  ? 30  THR E CB  1 
ATOM   14431 O OG1 . THR E 1 30  ? 62.375  50.982  57.693  1.00 38.15  ? 30  THR E OG1 1 
ATOM   14432 C CG2 . THR E 1 30  ? 63.464  49.084  56.739  1.00 34.45  ? 30  THR E CG2 1 
ATOM   14433 N N   . MET E 1 31  ? 64.096  52.562  59.814  1.00 31.08  ? 31  MET E N   1 
ATOM   14434 C CA  . MET E 1 31  ? 64.224  53.962  60.203  1.00 34.43  ? 31  MET E CA  1 
ATOM   14435 C C   . MET E 1 31  ? 63.325  54.288  61.404  1.00 35.67  ? 31  MET E C   1 
ATOM   14436 O O   . MET E 1 31  ? 62.527  53.456  61.859  1.00 34.69  ? 31  MET E O   1 
ATOM   14437 C CB  . MET E 1 31  ? 63.848  54.912  59.059  1.00 34.87  ? 31  MET E CB  1 
ATOM   14438 C CG  . MET E 1 31  ? 62.420  54.720  58.533  1.00 35.34  ? 31  MET E CG  1 
ATOM   14439 S SD  . MET E 1 31  ? 62.096  55.612  56.998  1.00 31.63  ? 31  MET E SD  1 
ATOM   14440 C CE  . MET E 1 31  ? 62.106  57.342  57.500  1.00 28.43  ? 31  MET E CE  1 
ATOM   14441 N N   . ASP E 1 32  ? 63.485  55.511  61.928  1.00 33.72  ? 32  ASP E N   1 
ATOM   14442 C CA  . ASP E 1 32  ? 62.650  55.984  63.009  1.00 38.78  ? 32  ASP E CA  1 
ATOM   14443 C C   . ASP E 1 32  ? 61.377  56.574  62.403  1.00 42.69  ? 32  ASP E C   1 
ATOM   14444 O O   . ASP E 1 32  ? 61.463  57.379  61.473  1.00 46.55  ? 32  ASP E O   1 
ATOM   14445 C CB  . ASP E 1 32  ? 63.381  57.017  63.864  1.00 39.73  ? 32  ASP E CB  1 
ATOM   14446 C CG  . ASP E 1 32  ? 64.516  56.521  64.755  1.00 37.13  ? 32  ASP E CG  1 
ATOM   14447 O OD1 . ASP E 1 32  ? 64.599  55.298  65.020  1.00 34.12  ? 32  ASP E OD1 1 
ATOM   14448 O OD2 . ASP E 1 32  ? 65.312  57.381  65.178  1.00 39.76  ? 32  ASP E OD2 1 
ATOM   14449 N N   . CYS E 1 33  ? 60.213  56.184  62.947  1.00 38.80  ? 33  CYS E N   1 
ATOM   14450 C CA  . CYS E 1 33  ? 58.961  56.881  62.682  1.00 34.94  ? 33  CYS E CA  1 
ATOM   14451 C C   . CYS E 1 33  ? 58.808  58.021  63.686  1.00 33.78  ? 33  CYS E C   1 
ATOM   14452 O O   . CYS E 1 33  ? 58.923  57.774  64.884  1.00 36.75  ? 33  CYS E O   1 
ATOM   14453 C CB  . CYS E 1 33  ? 57.791  55.905  62.748  1.00 36.64  ? 33  CYS E CB  1 
ATOM   14454 S SG  . CYS E 1 33  ? 56.216  56.589  62.179  1.00 37.81  ? 33  CYS E SG  1 
ATOM   14455 N N   . THR E 1 34  ? 58.498  59.237  63.210  1.00 29.59  ? 34  THR E N   1 
ATOM   14456 C CA  . THR E 1 34  ? 58.454  60.413  64.058  1.00 30.89  ? 34  THR E CA  1 
ATOM   14457 C C   . THR E 1 34  ? 57.083  61.095  64.006  1.00 32.75  ? 34  THR E C   1 
ATOM   14458 O O   . THR E 1 34  ? 56.314  60.940  63.062  1.00 30.28  ? 34  THR E O   1 
ATOM   14459 C CB  . THR E 1 34  ? 59.523  61.411  63.622  1.00 35.02  ? 34  THR E CB  1 
ATOM   14460 O OG1 . THR E 1 34  ? 59.199  61.803  62.287  1.00 36.06  ? 34  THR E OG1 1 
ATOM   14461 C CG2 . THR E 1 34  ? 60.917  60.810  63.655  1.00 40.87  ? 34  THR E CG2 1 
ATOM   14462 N N   . ILE E 1 35  ? 56.830  61.944  65.011  1.00 30.98  ? 35  ILE E N   1 
ATOM   14463 C CA  . ILE E 1 35  ? 55.767  62.924  64.927  1.00 33.15  ? 35  ILE E CA  1 
ATOM   14464 C C   . ILE E 1 35  ? 55.800  63.535  63.537  1.00 29.88  ? 35  ILE E C   1 
ATOM   14465 O O   . ILE E 1 35  ? 54.757  63.712  62.943  1.00 33.01  ? 35  ILE E O   1 
ATOM   14466 C CB  . ILE E 1 35  ? 55.895  64.001  66.019  1.00 35.82  ? 35  ILE E CB  1 
ATOM   14467 C CG1 . ILE E 1 35  ? 55.772  63.399  67.417  1.00 43.25  ? 35  ILE E CG1 1 
ATOM   14468 C CG2 . ILE E 1 35  ? 54.882  65.121  65.837  1.00 33.24  ? 35  ILE E CG2 1 
ATOM   14469 C CD1 . ILE E 1 35  ? 54.480  62.637  67.661  1.00 42.67  ? 35  ILE E CD1 1 
ATOM   14470 N N   . GLY E 1 36  ? 56.999  63.837  63.048  1.00 29.79  ? 36  GLY E N   1 
ATOM   14471 C CA  . GLY E 1 36  ? 57.195  64.635  61.851  1.00 30.62  ? 36  GLY E CA  1 
ATOM   14472 C C   . GLY E 1 36  ? 56.597  63.959  60.622  1.00 29.82  ? 36  GLY E C   1 
ATOM   14473 O O   . GLY E 1 36  ? 55.941  64.623  59.844  1.00 29.68  ? 36  GLY E O   1 
ATOM   14474 N N   . HIS E 1 37  ? 56.766  62.636  60.507  1.00 28.54  ? 37  HIS E N   1 
ATOM   14475 C CA  . HIS E 1 37  ? 56.080  61.849  59.503  1.00 31.44  ? 37  HIS E CA  1 
ATOM   14476 C C   . HIS E 1 37  ? 54.563  62.077  59.592  1.00 34.32  ? 37  HIS E C   1 
ATOM   14477 O O   . HIS E 1 37  ? 53.951  62.387  58.575  1.00 41.08  ? 37  HIS E O   1 
ATOM   14478 C CB  . HIS E 1 37  ? 56.509  60.375  59.577  1.00 35.34  ? 37  HIS E CB  1 
ATOM   14479 C CG  . HIS E 1 37  ? 57.988  60.149  59.412  1.00 42.87  ? 37  HIS E CG  1 
ATOM   14480 N ND1 . HIS E 1 37  ? 58.701  60.595  58.317  1.00 45.57  ? 37  HIS E ND1 1 
ATOM   14481 C CD2 . HIS E 1 37  ? 58.891  59.524  60.198  1.00 42.31  ? 37  HIS E CD2 1 
ATOM   14482 C CE1 . HIS E 1 37  ? 59.981  60.266  58.456  1.00 45.56  ? 37  HIS E CE1 1 
ATOM   14483 N NE2 . HIS E 1 37  ? 60.113  59.602  59.585  1.00 47.30  ? 37  HIS E NE2 1 
ATOM   14484 N N   . ALA E 1 38  ? 53.933  61.956  60.776  1.00 32.97  ? 38  ALA E N   1 
ATOM   14485 C CA  . ALA E 1 38  ? 52.473  62.008  60.844  1.00 31.22  ? 38  ALA E CA  1 
ATOM   14486 C C   . ALA E 1 38  ? 51.929  63.357  60.361  1.00 31.58  ? 38  ALA E C   1 
ATOM   14487 O O   . ALA E 1 38  ? 51.023  63.392  59.534  1.00 31.09  ? 38  ALA E O   1 
ATOM   14488 C CB  . ALA E 1 38  ? 51.997  61.691  62.218  1.00 32.31  ? 38  ALA E CB  1 
ATOM   14489 N N   . TYR E 1 39  ? 52.537  64.467  60.788  1.00 28.14  ? 39  TYR E N   1 
ATOM   14490 C CA  . TYR E 1 39  ? 52.143  65.781  60.306  1.00 29.55  ? 39  TYR E CA  1 
ATOM   14491 C C   . TYR E 1 39  ? 52.837  66.198  59.002  1.00 31.11  ? 39  TYR E C   1 
ATOM   14492 O O   . TYR E 1 39  ? 52.663  67.337  58.558  1.00 28.22  ? 39  TYR E O   1 
ATOM   14493 C CB  . TYR E 1 39  ? 52.473  66.812  61.382  1.00 29.56  ? 39  TYR E CB  1 
ATOM   14494 C CG  . TYR E 1 39  ? 51.597  66.655  62.611  1.00 32.01  ? 39  TYR E CG  1 
ATOM   14495 C CD1 . TYR E 1 39  ? 51.917  65.742  63.604  1.00 32.78  ? 39  TYR E CD1 1 
ATOM   14496 C CD2 . TYR E 1 39  ? 50.453  67.430  62.778  1.00 35.50  ? 39  TYR E CD2 1 
ATOM   14497 C CE1 . TYR E 1 39  ? 51.104  65.583  64.716  1.00 37.31  ? 39  TYR E CE1 1 
ATOM   14498 C CE2 . TYR E 1 39  ? 49.634  67.288  63.891  1.00 37.93  ? 39  TYR E CE2 1 
ATOM   14499 C CZ  . TYR E 1 39  ? 49.952  66.344  64.854  1.00 38.17  ? 39  TYR E CZ  1 
ATOM   14500 O OH  . TYR E 1 39  ? 49.183  66.210  65.965  1.00 33.42  ? 39  TYR E OH  1 
ATOM   14501 N N   . GLY E 1 40  ? 53.640  65.316  58.388  1.00 32.80  ? 40  GLY E N   1 
ATOM   14502 C CA  . GLY E 1 40  ? 54.434  65.701  57.223  1.00 33.15  ? 40  GLY E CA  1 
ATOM   14503 C C   . GLY E 1 40  ? 54.184  64.794  56.019  1.00 34.01  ? 40  GLY E C   1 
ATOM   14504 O O   . GLY E 1 40  ? 55.069  64.577  55.191  1.00 36.31  ? 40  GLY E O   1 
ATOM   14505 N N   . GLY E 1 41  ? 52.953  64.282  55.930  1.00 32.24  ? 41  GLY E N   1 
ATOM   14506 C CA  . GLY E 1 41  ? 52.509  63.504  54.797  1.00 29.05  ? 41  GLY E CA  1 
ATOM   14507 C C   . GLY E 1 41  ? 53.392  62.282  54.596  1.00 28.54  ? 41  GLY E C   1 
ATOM   14508 O O   . GLY E 1 41  ? 53.556  61.827  53.471  1.00 30.14  ? 41  GLY E O   1 
ATOM   14509 N N   . MET E 1 42  ? 53.957  61.767  55.688  1.00 26.40  ? 42  MET E N   1 
ATOM   14510 C CA  . MET E 1 42  ? 54.782  60.565  55.674  1.00 27.78  ? 42  MET E CA  1 
ATOM   14511 C C   . MET E 1 42  ? 56.083  60.705  54.865  1.00 26.88  ? 42  MET E C   1 
ATOM   14512 O O   . MET E 1 42  ? 56.664  59.689  54.473  1.00 25.24  ? 42  MET E O   1 
ATOM   14513 C CB  . MET E 1 42  ? 54.047  59.385  55.037  1.00 27.75  ? 42  MET E CB  1 
ATOM   14514 C CG  . MET E 1 42  ? 52.677  59.109  55.545  1.00 26.50  ? 42  MET E CG  1 
ATOM   14515 S SD  . MET E 1 42  ? 52.302  57.442  54.984  1.00 28.99  ? 42  MET E SD  1 
ATOM   14516 C CE  . MET E 1 42  ? 50.585  57.279  55.471  1.00 27.61  ? 42  MET E CE  1 
ATOM   14517 N N   . ARG E 1 43  ? 56.570  61.933  54.664  1.00 28.82  ? 43  ARG E N   1 
ATOM   14518 C CA  . ARG E 1 43  ? 57.757  62.173  53.849  1.00 38.07  ? 43  ARG E CA  1 
ATOM   14519 C C   . ARG E 1 43  ? 58.925  61.293  54.293  1.00 34.20  ? 43  ARG E C   1 
ATOM   14520 O O   . ARG E 1 43  ? 59.500  61.529  55.337  1.00 36.63  ? 43  ARG E O   1 
ATOM   14521 C CB  . ARG E 1 43  ? 58.180  63.650  53.827  1.00 43.74  ? 43  ARG E CB  1 
ATOM   14522 C CG  . ARG E 1 43  ? 59.004  64.039  52.606  1.00 53.63  ? 43  ARG E CG  1 
ATOM   14523 C CD  . ARG E 1 43  ? 59.254  65.557  52.483  1.00 72.38  ? 43  ARG E CD  1 
ATOM   14524 N NE  . ARG E 1 43  ? 59.140  66.043  51.095  1.00 92.45  ? 43  ARG E NE  1 
ATOM   14525 C CZ  . ARG E 1 43  ? 58.199  66.874  50.590  1.00 101.49 ? 43  ARG E CZ  1 
ATOM   14526 N NH1 . ARG E 1 43  ? 57.342  67.508  51.376  1.00 97.22  ? 43  ARG E NH1 1 
ATOM   14527 N NH2 . ARG E 1 43  ? 58.125  67.093  49.284  1.00 98.85  ? 43  ARG E NH2 1 
ATOM   14528 N N   . GLY E 1 44  ? 59.306  60.312  53.461  1.00 36.03  ? 44  GLY E N   1 
ATOM   14529 C CA  . GLY E 1 44  ? 60.508  59.521  53.676  1.00 33.42  ? 44  GLY E CA  1 
ATOM   14530 C C   . GLY E 1 44  ? 60.186  58.167  54.303  1.00 35.63  ? 44  GLY E C   1 
ATOM   14531 O O   . GLY E 1 44  ? 61.048  57.297  54.387  1.00 34.19  ? 44  GLY E O   1 
ATOM   14532 N N   . LEU E 1 45  ? 58.935  57.976  54.733  1.00 33.12  ? 45  LEU E N   1 
ATOM   14533 C CA  . LEU E 1 45  ? 58.641  56.846  55.588  1.00 31.03  ? 45  LEU E CA  1 
ATOM   14534 C C   . LEU E 1 45  ? 58.522  55.594  54.724  1.00 29.91  ? 45  LEU E C   1 
ATOM   14535 O O   . LEU E 1 45  ? 57.591  55.438  53.954  1.00 34.69  ? 45  LEU E O   1 
ATOM   14536 C CB  . LEU E 1 45  ? 57.382  57.117  56.412  1.00 33.22  ? 45  LEU E CB  1 
ATOM   14537 C CG  . LEU E 1 45  ? 57.131  56.149  57.578  1.00 34.13  ? 45  LEU E CG  1 
ATOM   14538 C CD1 . LEU E 1 45  ? 58.101  56.365  58.728  1.00 35.56  ? 45  LEU E CD1 1 
ATOM   14539 C CD2 . LEU E 1 45  ? 55.724  56.243  58.076  1.00 34.93  ? 45  LEU E CD2 1 
ATOM   14540 N N   . LYS E 1 46  ? 59.470  54.680  54.868  1.00 28.67  ? 46  LYS E N   1 
ATOM   14541 C CA  . LYS E 1 46  ? 59.492  53.501  54.042  1.00 29.18  ? 46  LYS E CA  1 
ATOM   14542 C C   . LYS E 1 46  ? 58.337  52.600  54.429  1.00 30.67  ? 46  LYS E C   1 
ATOM   14543 O O   . LYS E 1 46  ? 58.569  51.595  55.069  1.00 28.85  ? 46  LYS E O   1 
ATOM   14544 C CB  . LYS E 1 46  ? 60.841  52.803  54.170  1.00 31.88  ? 46  LYS E CB  1 
ATOM   14545 C CG  . LYS E 1 46  ? 62.030  53.650  53.737  1.00 34.42  ? 46  LYS E CG  1 
ATOM   14546 C CD  . LYS E 1 46  ? 63.362  52.912  53.872  1.00 38.40  ? 46  LYS E CD  1 
ATOM   14547 C CE  . LYS E 1 46  ? 64.518  53.821  54.157  1.00 45.36  ? 46  LYS E CE  1 
ATOM   14548 N NZ  . LYS E 1 46  ? 65.095  54.422  52.961  1.00 47.04  ? 46  LYS E NZ  1 
ATOM   14549 N N   . ALA E 1 47  ? 57.132  52.916  53.921  1.00 39.51  ? 47  ALA E N   1 
ATOM   14550 C CA  . ALA E 1 47  ? 55.883  52.255  54.303  1.00 39.51  ? 47  ALA E CA  1 
ATOM   14551 C C   . ALA E 1 47  ? 55.247  51.370  53.217  1.00 37.29  ? 47  ALA E C   1 
ATOM   14552 O O   . ALA E 1 47  ? 54.257  50.693  53.495  1.00 38.72  ? 47  ALA E O   1 
ATOM   14553 C CB  . ALA E 1 47  ? 54.904  53.321  54.741  1.00 37.55  ? 47  ALA E CB  1 
ATOM   14554 N N   . LEU E 1 48  ? 55.776  51.375  51.983  1.00 36.77  ? 48  LEU E N   1 
ATOM   14555 C CA  . LEU E 1 48  ? 55.146  50.702  50.847  1.00 37.49  ? 48  LEU E CA  1 
ATOM   14556 C C   . LEU E 1 48  ? 56.163  49.816  50.153  1.00 35.23  ? 48  LEU E C   1 
ATOM   14557 O O   . LEU E 1 48  ? 57.339  50.119  50.201  1.00 38.04  ? 48  LEU E O   1 
ATOM   14558 C CB  . LEU E 1 48  ? 54.663  51.721  49.818  1.00 37.33  ? 48  LEU E CB  1 
ATOM   14559 C CG  . LEU E 1 48  ? 53.423  52.510  50.203  1.00 39.20  ? 48  LEU E CG  1 
ATOM   14560 C CD1 . LEU E 1 48  ? 53.227  53.627  49.234  1.00 39.16  ? 48  LEU E CD1 1 
ATOM   14561 C CD2 . LEU E 1 48  ? 52.225  51.578  50.263  1.00 42.75  ? 48  LEU E CD2 1 
ATOM   14562 N N   . VAL E 1 49  ? 55.678  48.805  49.431  1.00 35.41  ? 49  VAL E N   1 
ATOM   14563 C CA  . VAL E 1 49  ? 56.498  47.983  48.555  1.00 36.11  ? 49  VAL E CA  1 
ATOM   14564 C C   . VAL E 1 49  ? 56.083  48.204  47.099  1.00 38.64  ? 49  VAL E C   1 
ATOM   14565 O O   . VAL E 1 49  ? 54.895  48.133  46.766  1.00 34.92  ? 49  VAL E O   1 
ATOM   14566 C CB  . VAL E 1 49  ? 56.346  46.497  48.917  1.00 36.93  ? 49  VAL E CB  1 
ATOM   14567 C CG1 . VAL E 1 49  ? 56.961  45.595  47.851  1.00 35.81  ? 49  VAL E CG1 1 
ATOM   14568 C CG2 . VAL E 1 49  ? 56.886  46.208  50.307  1.00 34.40  ? 49  VAL E CG2 1 
ATOM   14569 N N   . CYS E 1 50  ? 57.089  48.438  46.244  1.00 36.00  ? 50  CYS E N   1 
ATOM   14570 C CA  . CYS E 1 50  ? 56.907  48.595  44.809  1.00 31.77  ? 50  CYS E CA  1 
ATOM   14571 C C   . CYS E 1 50  ? 58.119  48.024  44.091  1.00 31.95  ? 50  CYS E C   1 
ATOM   14572 O O   . CYS E 1 50  ? 59.219  48.575  44.219  1.00 29.85  ? 50  CYS E O   1 
ATOM   14573 C CB  . CYS E 1 50  ? 56.820  50.059  44.392  1.00 30.31  ? 50  CYS E CB  1 
ATOM   14574 S SG  . CYS E 1 50  ? 56.957  50.278  42.596  1.00 28.43  ? 50  CYS E SG  1 
ATOM   14575 N N   . ASP E 1 51  ? 57.897  46.943  43.336  1.00 33.33  ? 51  ASP E N   1 
ATOM   14576 C CA  . ASP E 1 51  ? 58.985  46.238  42.672  1.00 32.38  ? 51  ASP E CA  1 
ATOM   14577 C C   . ASP E 1 51  ? 59.027  46.528  41.178  1.00 31.86  ? 51  ASP E C   1 
ATOM   14578 O O   . ASP E 1 51  ? 59.748  45.835  40.470  1.00 33.58  ? 51  ASP E O   1 
ATOM   14579 C CB  . ASP E 1 51  ? 58.900  44.727  42.832  1.00 30.08  ? 51  ASP E CB  1 
ATOM   14580 C CG  . ASP E 1 51  ? 59.339  44.215  44.189  1.00 28.82  ? 51  ASP E CG  1 
ATOM   14581 O OD1 . ASP E 1 51  ? 60.260  44.835  44.744  1.00 27.86  ? 51  ASP E OD1 1 
ATOM   14582 O OD2 . ASP E 1 51  ? 58.784  43.188  44.643  1.00 27.89  ? 51  ASP E OD2 1 
ATOM   14583 N N   . THR E 1 52  ? 58.274  47.527  40.695  1.00 32.87  ? 52  THR E N   1 
ATOM   14584 C CA  . THR E 1 52  ? 58.225  47.802  39.261  1.00 29.69  ? 52  THR E CA  1 
ATOM   14585 C C   . THR E 1 52  ? 59.314  48.808  38.891  1.00 25.87  ? 52  THR E C   1 
ATOM   14586 O O   . THR E 1 52  ? 59.918  48.679  37.837  1.00 24.16  ? 52  THR E O   1 
ATOM   14587 C CB  . THR E 1 52  ? 56.842  48.276  38.810  1.00 29.22  ? 52  THR E CB  1 
ATOM   14588 O OG1 . THR E 1 52  ? 56.552  49.367  39.678  1.00 27.92  ? 52  THR E OG1 1 
ATOM   14589 C CG2 . THR E 1 52  ? 55.789  47.184  38.881  1.00 28.77  ? 52  THR E CG2 1 
ATOM   14590 N N   . SER E 1 53  ? 59.563  49.814  39.737  1.00 26.95  ? 53  SER E N   1 
ATOM   14591 C CA  . SER E 1 53  ? 60.598  50.806  39.467  1.00 27.14  ? 53  SER E CA  1 
ATOM   14592 C C   . SER E 1 53  ? 61.219  51.334  40.768  1.00 30.33  ? 53  SER E C   1 
ATOM   14593 O O   . SER E 1 53  ? 60.602  51.286  41.815  1.00 35.41  ? 53  SER E O   1 
ATOM   14594 C CB  . SER E 1 53  ? 60.060  51.922  38.608  1.00 26.51  ? 53  SER E CB  1 
ATOM   14595 O OG  . SER E 1 53  ? 58.988  52.634  39.219  1.00 26.36  ? 53  SER E OG  1 
ATOM   14596 N N   . GLU E 1 54  ? 62.443  51.872  40.685  1.00 32.14  ? 54  GLU E N   1 
ATOM   14597 C CA  . GLU E 1 54  ? 63.201  52.340  41.831  1.00 30.17  ? 54  GLU E CA  1 
ATOM   14598 C C   . GLU E 1 54  ? 63.995  53.573  41.418  1.00 30.07  ? 54  GLU E C   1 
ATOM   14599 O O   . GLU E 1 54  ? 64.551  53.611  40.335  1.00 29.29  ? 54  GLU E O   1 
ATOM   14600 C CB  . GLU E 1 54  ? 64.121  51.197  42.257  1.00 31.63  ? 54  GLU E CB  1 
ATOM   14601 C CG  . GLU E 1 54  ? 64.889  51.443  43.556  1.00 31.62  ? 54  GLU E CG  1 
ATOM   14602 C CD  . GLU E 1 54  ? 65.632  50.231  44.132  1.00 33.26  ? 54  GLU E CD  1 
ATOM   14603 O OE1 . GLU E 1 54  ? 66.174  50.466  45.239  1.00 35.25  ? 54  GLU E OE1 1 
ATOM   14604 O OE2 . GLU E 1 54  ? 65.697  49.101  43.554  1.00 30.12  ? 54  GLU E OE2 1 
ATOM   14605 N N   . VAL E 1 55  ? 64.061  54.584  42.279  1.00 32.45  ? 55  VAL E N   1 
ATOM   14606 C CA  . VAL E 1 55  ? 64.760  55.809  41.938  1.00 35.51  ? 55  VAL E CA  1 
ATOM   14607 C C   . VAL E 1 55  ? 66.164  55.752  42.538  1.00 35.06  ? 55  VAL E C   1 
ATOM   14608 O O   . VAL E 1 55  ? 66.297  55.479  43.717  1.00 35.66  ? 55  VAL E O   1 
ATOM   14609 C CB  . VAL E 1 55  ? 63.943  57.014  42.451  1.00 39.54  ? 55  VAL E CB  1 
ATOM   14610 C CG1 . VAL E 1 55  ? 64.708  58.329  42.318  1.00 42.14  ? 55  VAL E CG1 1 
ATOM   14611 C CG2 . VAL E 1 55  ? 62.591  57.117  41.750  1.00 40.63  ? 55  VAL E CG2 1 
ATOM   14612 N N   . PHE E 1 56  ? 67.215  55.994  41.741  1.00 37.59  ? 56  PHE E N   1 
ATOM   14613 C CA  . PHE E 1 56  ? 68.575  56.092  42.273  1.00 34.78  ? 56  PHE E CA  1 
ATOM   14614 C C   . PHE E 1 56  ? 69.018  57.548  42.166  1.00 34.19  ? 56  PHE E C   1 
ATOM   14615 O O   . PHE E 1 56  ? 69.016  58.115  41.087  1.00 35.02  ? 56  PHE E O   1 
ATOM   14616 C CB  . PHE E 1 56  ? 69.555  55.143  41.584  1.00 30.60  ? 56  PHE E CB  1 
ATOM   14617 C CG  . PHE E 1 56  ? 69.192  53.685  41.784  1.00 31.07  ? 56  PHE E CG  1 
ATOM   14618 C CD1 . PHE E 1 56  ? 68.158  53.101  41.052  1.00 33.33  ? 56  PHE E CD1 1 
ATOM   14619 C CD2 . PHE E 1 56  ? 69.865  52.908  42.710  1.00 30.50  ? 56  PHE E CD2 1 
ATOM   14620 C CE1 . PHE E 1 56  ? 67.831  51.760  41.216  1.00 33.38  ? 56  PHE E CE1 1 
ATOM   14621 C CE2 . PHE E 1 56  ? 69.536  51.571  42.872  1.00 32.91  ? 56  PHE E CE2 1 
ATOM   14622 C CZ  . PHE E 1 56  ? 68.518  50.999  42.126  1.00 35.15  ? 56  PHE E CZ  1 
ATOM   14623 N N   . PRO E 1 57  ? 69.317  58.219  43.299  1.00 36.73  ? 57  PRO E N   1 
ATOM   14624 C CA  . PRO E 1 57  ? 69.625  59.649  43.305  1.00 35.53  ? 57  PRO E CA  1 
ATOM   14625 C C   . PRO E 1 57  ? 70.719  60.101  42.362  1.00 35.80  ? 57  PRO E C   1 
ATOM   14626 O O   . PRO E 1 57  ? 70.726  61.258  41.950  1.00 38.77  ? 57  PRO E O   1 
ATOM   14627 C CB  . PRO E 1 57  ? 70.046  59.875  44.770  1.00 37.32  ? 57  PRO E CB  1 
ATOM   14628 C CG  . PRO E 1 57  ? 69.199  58.909  45.532  1.00 38.28  ? 57  PRO E CG  1 
ATOM   14629 C CD  . PRO E 1 57  ? 69.239  57.658  44.660  1.00 38.30  ? 57  PRO E CD  1 
ATOM   14630 N N   . ASP E 1 58  ? 71.645  59.185  42.064  1.00 38.20  ? 58  ASP E N   1 
ATOM   14631 C CA  . ASP E 1 58  ? 72.792  59.506  41.226  1.00 42.59  ? 58  ASP E CA  1 
ATOM   14632 C C   . ASP E 1 58  ? 72.649  59.012  39.781  1.00 38.71  ? 58  ASP E C   1 
ATOM   14633 O O   . ASP E 1 58  ? 73.556  59.260  39.000  1.00 34.77  ? 58  ASP E O   1 
ATOM   14634 C CB  . ASP E 1 58  ? 74.080  59.015  41.869  1.00 43.13  ? 58  ASP E CB  1 
ATOM   14635 C CG  . ASP E 1 58  ? 74.475  59.748  43.139  1.00 44.11  ? 58  ASP E CG  1 
ATOM   14636 O OD1 . ASP E 1 58  ? 74.059  60.914  43.304  1.00 46.73  ? 58  ASP E OD1 1 
ATOM   14637 O OD2 . ASP E 1 58  ? 75.135  59.119  43.976  1.00 47.58  ? 58  ASP E OD2 1 
ATOM   14638 N N   . GLU E 1 59  ? 71.531  58.359  39.418  1.00 36.56  ? 59  GLU E N   1 
ATOM   14639 C CA  . GLU E 1 59  ? 71.353  57.816  38.077  1.00 38.37  ? 59  GLU E CA  1 
ATOM   14640 C C   . GLU E 1 59  ? 69.994  58.207  37.500  1.00 39.50  ? 59  GLU E C   1 
ATOM   14641 O O   . GLU E 1 59  ? 69.925  58.644  36.341  1.00 38.56  ? 59  GLU E O   1 
ATOM   14642 C CB  . GLU E 1 59  ? 71.434  56.292  38.058  1.00 36.34  ? 59  GLU E CB  1 
ATOM   14643 C CG  . GLU E 1 59  ? 72.793  55.788  38.518  1.00 35.62  ? 59  GLU E CG  1 
ATOM   14644 C CD  . GLU E 1 59  ? 72.880  54.279  38.435  1.00 34.01  ? 59  GLU E CD  1 
ATOM   14645 O OE1 . GLU E 1 59  ? 72.953  53.758  37.303  1.00 30.99  ? 59  GLU E OE1 1 
ATOM   14646 O OE2 . GLU E 1 59  ? 72.833  53.633  39.509  1.00 31.88  ? 59  GLU E OE2 1 
ATOM   14647 N N   . GLY E 1 60  ? 68.945  57.991  38.316  1.00 34.89  ? 60  GLY E N   1 
ATOM   14648 C CA  . GLY E 1 60  ? 67.559  58.335  38.017  1.00 33.33  ? 60  GLY E CA  1 
ATOM   14649 C C   . GLY E 1 60  ? 66.674  57.104  38.195  1.00 32.53  ? 60  GLY E C   1 
ATOM   14650 O O   . GLY E 1 60  ? 67.124  56.091  38.721  1.00 34.65  ? 60  GLY E O   1 
ATOM   14651 N N   . VAL E 1 61  ? 65.436  57.140  37.706  1.00 30.31  ? 61  VAL E N   1 
ATOM   14652 C CA  . VAL E 1 61  ? 64.593  55.962  37.828  1.00 28.51  ? 61  VAL E CA  1 
ATOM   14653 C C   . VAL E 1 61  ? 65.102  54.821  36.946  1.00 28.63  ? 61  VAL E C   1 
ATOM   14654 O O   . VAL E 1 61  ? 65.681  55.043  35.887  1.00 30.08  ? 61  VAL E O   1 
ATOM   14655 C CB  . VAL E 1 61  ? 63.150  56.322  37.471  1.00 29.31  ? 61  VAL E CB  1 
ATOM   14656 C CG1 . VAL E 1 61  ? 62.991  56.561  35.973  1.00 31.36  ? 61  VAL E CG1 1 
ATOM   14657 C CG2 . VAL E 1 61  ? 62.211  55.230  37.933  1.00 31.97  ? 61  VAL E CG2 1 
ATOM   14658 N N   . LYS E 1 62  ? 64.850  53.592  37.390  1.00 26.39  ? 62  LYS E N   1 
ATOM   14659 C CA  . LYS E 1 62  ? 65.176  52.392  36.640  1.00 28.67  ? 62  LYS E CA  1 
ATOM   14660 C C   . LYS E 1 62  ? 63.952  51.481  36.625  1.00 29.57  ? 62  LYS E C   1 
ATOM   14661 O O   . LYS E 1 62  ? 63.295  51.347  37.645  1.00 27.58  ? 62  LYS E O   1 
ATOM   14662 C CB  . LYS E 1 62  ? 66.312  51.620  37.328  1.00 29.97  ? 62  LYS E CB  1 
ATOM   14663 C CG  . LYS E 1 62  ? 67.664  52.336  37.308  1.00 32.56  ? 62  LYS E CG  1 
ATOM   14664 C CD  . LYS E 1 62  ? 68.855  51.457  37.685  1.00 32.76  ? 62  LYS E CD  1 
ATOM   14665 C CE  . LYS E 1 62  ? 70.022  52.324  38.061  1.00 35.92  ? 62  LYS E CE  1 
ATOM   14666 N NZ  . LYS E 1 62  ? 71.222  51.541  38.399  1.00 37.65  ? 62  LYS E NZ  1 
ATOM   14667 N N   . PHE E 1 63  ? 63.686  50.825  35.490  1.00 28.25  ? 63  PHE E N   1 
ATOM   14668 C CA  . PHE E 1 63  ? 62.565  49.913  35.362  1.00 30.74  ? 63  PHE E CA  1 
ATOM   14669 C C   . PHE E 1 63  ? 63.077  48.481  35.462  1.00 33.81  ? 63  PHE E C   1 
ATOM   14670 O O   . PHE E 1 63  ? 63.733  47.989  34.539  1.00 44.52  ? 63  PHE E O   1 
ATOM   14671 C CB  . PHE E 1 63  ? 61.872  50.119  34.014  1.00 31.53  ? 63  PHE E CB  1 
ATOM   14672 C CG  . PHE E 1 63  ? 61.351  51.525  33.764  1.00 32.10  ? 63  PHE E CG  1 
ATOM   14673 C CD1 . PHE E 1 63  ? 60.697  52.237  34.760  1.00 32.92  ? 63  PHE E CD1 1 
ATOM   14674 C CD2 . PHE E 1 63  ? 61.483  52.121  32.523  1.00 32.83  ? 63  PHE E CD2 1 
ATOM   14675 C CE1 . PHE E 1 63  ? 60.193  53.507  34.509  1.00 30.51  ? 63  PHE E CE1 1 
ATOM   14676 C CE2 . PHE E 1 63  ? 60.981  53.394  32.282  1.00 31.86  ? 63  PHE E CE2 1 
ATOM   14677 C CZ  . PHE E 1 63  ? 60.329  54.078  33.270  1.00 29.28  ? 63  PHE E CZ  1 
ATOM   14678 N N   . ARG E 1 64  ? 62.780  47.819  36.580  1.00 28.73  ? 64  ARG E N   1 
ATOM   14679 C CA  . ARG E 1 64  ? 63.162  46.435  36.804  1.00 30.07  ? 64  ARG E CA  1 
ATOM   14680 C C   . ARG E 1 64  ? 64.666  46.254  36.648  1.00 32.55  ? 64  ARG E C   1 
ATOM   14681 O O   . ARG E 1 64  ? 65.119  45.213  36.162  1.00 37.77  ? 64  ARG E O   1 
ATOM   14682 C CB  . ARG E 1 64  ? 62.380  45.461  35.921  1.00 30.33  ? 64  ARG E CB  1 
ATOM   14683 C CG  . ARG E 1 64  ? 60.956  45.259  36.417  1.00 32.95  ? 64  ARG E CG  1 
ATOM   14684 C CD  . ARG E 1 64  ? 60.864  44.518  37.772  1.00 32.17  ? 64  ARG E CD  1 
ATOM   14685 N NE  . ARG E 1 64  ? 59.513  43.969  37.958  1.00 33.34  ? 64  ARG E NE  1 
ATOM   14686 C CZ  . ARG E 1 64  ? 59.165  42.997  38.798  1.00 34.51  ? 64  ARG E CZ  1 
ATOM   14687 N NH1 . ARG E 1 64  ? 60.005  42.641  39.747  1.00 38.97  ? 64  ARG E NH1 1 
ATOM   14688 N NH2 . ARG E 1 64  ? 57.979  42.410  38.723  1.00 30.38  ? 64  ARG E NH2 1 
ATOM   14689 N N   . GLY E 1 65  ? 65.422  47.244  37.138  1.00 35.69  ? 65  GLY E N   1 
ATOM   14690 C CA  . GLY E 1 65  ? 66.877  47.175  37.184  1.00 37.57  ? 65  GLY E CA  1 
ATOM   14691 C C   . GLY E 1 65  ? 67.542  47.929  36.032  1.00 36.31  ? 65  GLY E C   1 
ATOM   14692 O O   . GLY E 1 65  ? 68.708  48.287  36.146  1.00 39.33  ? 65  GLY E O   1 
ATOM   14693 N N   . TYR E 1 66  ? 66.781  48.201  34.957  1.00 33.09  ? 66  TYR E N   1 
ATOM   14694 C CA  . TYR E 1 66  ? 67.318  48.679  33.693  1.00 27.95  ? 66  TYR E CA  1 
ATOM   14695 C C   . TYR E 1 66  ? 67.154  50.186  33.551  1.00 26.94  ? 66  TYR E C   1 
ATOM   14696 O O   . TYR E 1 66  ? 66.131  50.750  33.908  1.00 26.70  ? 66  TYR E O   1 
ATOM   14697 C CB  . TYR E 1 66  ? 66.571  48.011  32.552  1.00 26.33  ? 66  TYR E CB  1 
ATOM   14698 C CG  . TYR E 1 66  ? 66.806  46.519  32.487  1.00 25.71  ? 66  TYR E CG  1 
ATOM   14699 C CD1 . TYR E 1 66  ? 67.971  46.004  31.939  1.00 29.63  ? 66  TYR E CD1 1 
ATOM   14700 C CD2 . TYR E 1 66  ? 65.830  45.623  32.880  1.00 28.11  ? 66  TYR E CD2 1 
ATOM   14701 C CE1 . TYR E 1 66  ? 68.174  44.636  31.832  1.00 28.53  ? 66  TYR E CE1 1 
ATOM   14702 C CE2 . TYR E 1 66  ? 66.026  44.256  32.799  1.00 27.70  ? 66  TYR E CE2 1 
ATOM   14703 C CZ  . TYR E 1 66  ? 67.206  43.763  32.283  1.00 26.33  ? 66  TYR E CZ  1 
ATOM   14704 O OH  . TYR E 1 66  ? 67.411  42.427  32.197  1.00 27.77  ? 66  TYR E OH  1 
ATOM   14705 N N   . THR E 1 67  ? 68.196  50.852  33.061  1.00 28.84  ? 67  THR E N   1 
ATOM   14706 C CA  . THR E 1 67  ? 68.160  52.298  32.955  1.00 28.61  ? 67  THR E CA  1 
ATOM   14707 C C   . THR E 1 67  ? 67.357  52.627  31.713  1.00 28.92  ? 67  THR E C   1 
ATOM   14708 O O   . THR E 1 67  ? 67.080  51.749  30.901  1.00 29.64  ? 67  THR E O   1 
ATOM   14709 C CB  . THR E 1 67  ? 69.566  52.890  32.870  1.00 32.29  ? 67  THR E CB  1 
ATOM   14710 O OG1 . THR E 1 67  ? 70.127  52.448  31.636  1.00 33.20  ? 67  THR E OG1 1 
ATOM   14711 C CG2 . THR E 1 67  ? 70.457  52.498  34.038  1.00 31.53  ? 67  THR E CG2 1 
ATOM   14712 N N   . ILE E 1 68  ? 67.013  53.900  31.567  1.00 27.88  ? 68  ILE E N   1 
ATOM   14713 C CA  . ILE E 1 68  ? 66.309  54.327  30.380  1.00 29.59  ? 68  ILE E CA  1 
ATOM   14714 C C   . ILE E 1 68  ? 67.224  54.209  29.160  1.00 30.17  ? 68  ILE E C   1 
ATOM   14715 O O   . ILE E 1 68  ? 66.779  53.642  28.157  1.00 30.88  ? 68  ILE E O   1 
ATOM   14716 C CB  . ILE E 1 68  ? 65.681  55.706  30.617  1.00 32.25  ? 68  ILE E CB  1 
ATOM   14717 C CG1 . ILE E 1 68  ? 64.346  55.495  31.374  1.00 34.33  ? 68  ILE E CG1 1 
ATOM   14718 C CG2 . ILE E 1 68  ? 65.517  56.477  29.309  1.00 31.66  ? 68  ILE E CG2 1 
ATOM   14719 C CD1 . ILE E 1 68  ? 63.779  56.733  32.038  1.00 34.78  ? 68  ILE E CD1 1 
ATOM   14720 N N   . PRO E 1 69  ? 68.512  54.660  29.192  1.00 28.36  ? 69  PRO E N   1 
ATOM   14721 C CA  . PRO E 1 69  ? 69.456  54.372  28.105  1.00 29.50  ? 69  PRO E CA  1 
ATOM   14722 C C   . PRO E 1 69  ? 69.518  52.905  27.691  1.00 29.19  ? 69  PRO E C   1 
ATOM   14723 O O   . PRO E 1 69  ? 69.432  52.600  26.517  1.00 33.02  ? 69  PRO E O   1 
ATOM   14724 C CB  . PRO E 1 69  ? 70.788  54.884  28.670  1.00 29.21  ? 69  PRO E CB  1 
ATOM   14725 C CG  . PRO E 1 69  ? 70.341  56.097  29.446  1.00 29.62  ? 69  PRO E CG  1 
ATOM   14726 C CD  . PRO E 1 69  ? 69.091  55.587  30.173  1.00 27.81  ? 69  PRO E CD  1 
ATOM   14727 N N   . GLU E 1 70  ? 69.575  51.983  28.648  1.00 28.04  ? 70  GLU E N   1 
ATOM   14728 C CA  . GLU E 1 70  ? 69.632  50.571  28.317  1.00 28.21  ? 70  GLU E CA  1 
ATOM   14729 C C   . GLU E 1 70  ? 68.465  50.136  27.427  1.00 30.99  ? 70  GLU E C   1 
ATOM   14730 O O   . GLU E 1 70  ? 68.617  49.259  26.584  1.00 28.65  ? 70  GLU E O   1 
ATOM   14731 C CB  . GLU E 1 70  ? 69.647  49.760  29.609  1.00 29.58  ? 70  GLU E CB  1 
ATOM   14732 C CG  . GLU E 1 70  ? 71.042  49.571  30.193  1.00 29.66  ? 70  GLU E CG  1 
ATOM   14733 C CD  . GLU E 1 70  ? 70.981  48.753  31.452  1.00 29.00  ? 70  GLU E CD  1 
ATOM   14734 O OE1 . GLU E 1 70  ? 71.519  47.641  31.523  1.00 34.42  ? 70  GLU E OE1 1 
ATOM   14735 O OE2 . GLU E 1 70  ? 70.317  49.240  32.356  1.00 31.66  ? 70  GLU E OE2 1 
ATOM   14736 N N   . LEU E 1 71  ? 67.280  50.713  27.654  1.00 36.49  ? 71  LEU E N   1 
ATOM   14737 C CA  . LEU E 1 71  ? 66.041  50.217  27.069  1.00 35.09  ? 71  LEU E CA  1 
ATOM   14738 C C   . LEU E 1 71  ? 65.722  50.961  25.782  1.00 30.59  ? 71  LEU E C   1 
ATOM   14739 O O   . LEU E 1 71  ? 65.079  50.419  24.896  1.00 23.80  ? 71  LEU E O   1 
ATOM   14740 C CB  . LEU E 1 71  ? 64.922  50.412  28.090  1.00 33.74  ? 71  LEU E CB  1 
ATOM   14741 C CG  . LEU E 1 71  ? 65.031  49.537  29.336  1.00 34.65  ? 71  LEU E CG  1 
ATOM   14742 C CD1 . LEU E 1 71  ? 64.020  50.006  30.355  1.00 37.32  ? 71  LEU E CD1 1 
ATOM   14743 C CD2 . LEU E 1 71  ? 64.834  48.073  29.001  1.00 35.42  ? 71  LEU E CD2 1 
ATOM   14744 N N   . ARG E 1 72  ? 66.134  52.226  25.734  1.00 31.98  ? 72  ARG E N   1 
ATOM   14745 C CA  . ARG E 1 72  ? 65.773  53.075  24.625  1.00 32.36  ? 72  ARG E CA  1 
ATOM   14746 C C   . ARG E 1 72  ? 66.827  52.944  23.541  1.00 35.09  ? 72  ARG E C   1 
ATOM   14747 O O   . ARG E 1 72  ? 66.455  52.841  22.387  1.00 35.71  ? 72  ARG E O   1 
ATOM   14748 C CB  . ARG E 1 72  ? 65.638  54.530  25.058  1.00 30.39  ? 72  ARG E CB  1 
ATOM   14749 C CG  . ARG E 1 72  ? 65.399  55.447  23.868  1.00 29.47  ? 72  ARG E CG  1 
ATOM   14750 C CD  . ARG E 1 72  ? 64.723  56.725  24.340  1.00 29.09  ? 72  ARG E CD  1 
ATOM   14751 N NE  . ARG E 1 72  ? 64.557  57.682  23.249  1.00 27.40  ? 72  ARG E NE  1 
ATOM   14752 C CZ  . ARG E 1 72  ? 65.435  58.545  22.823  1.00 30.51  ? 72  ARG E CZ  1 
ATOM   14753 N NH1 . ARG E 1 72  ? 66.576  58.725  23.468  1.00 32.35  ? 72  ARG E NH1 1 
ATOM   14754 N NH2 . ARG E 1 72  ? 65.143  59.250  21.751  1.00 31.61  ? 72  ARG E NH2 1 
ATOM   14755 N N   . GLU E 1 73  ? 68.112  52.961  23.931  1.00 35.35  ? 73  GLU E N   1 
ATOM   14756 C CA  . GLU E 1 73  ? 69.239  52.911  23.000  1.00 39.55  ? 73  GLU E CA  1 
ATOM   14757 C C   . GLU E 1 73  ? 70.092  51.659  23.209  1.00 39.40  ? 73  GLU E C   1 
ATOM   14758 O O   . GLU E 1 73  ? 70.357  50.911  22.259  1.00 29.75  ? 73  GLU E O   1 
ATOM   14759 C CB  . GLU E 1 73  ? 70.194  54.082  23.234  1.00 42.22  ? 73  GLU E CB  1 
ATOM   14760 C CG  . GLU E 1 73  ? 69.485  55.415  23.448  1.00 47.94  ? 73  GLU E CG  1 
ATOM   14761 C CD  . GLU E 1 73  ? 70.418  56.568  23.765  1.00 55.41  ? 73  GLU E CD  1 
ATOM   14762 O OE1 . GLU E 1 73  ? 70.673  56.839  24.969  1.00 56.87  ? 73  GLU E OE1 1 
ATOM   14763 O OE2 . GLU E 1 73  ? 70.844  57.221  22.786  1.00 62.44  ? 73  GLU E OE2 1 
ATOM   14764 N N   . GLY E 1 74  ? 70.387  51.440  24.504  1.00 45.26  ? 74  GLY E N   1 
ATOM   14765 C CA  . GLY E 1 74  ? 71.592  50.831  25.043  1.00 41.20  ? 74  GLY E CA  1 
ATOM   14766 C C   . GLY E 1 74  ? 71.558  49.360  24.722  1.00 41.27  ? 74  GLY E C   1 
ATOM   14767 O O   . GLY E 1 74  ? 70.888  48.976  23.768  1.00 53.64  ? 74  GLY E O   1 
ATOM   14768 N N   . PRO E 1 75  ? 72.273  48.505  25.472  1.00 36.05  ? 75  PRO E N   1 
ATOM   14769 C CA  . PRO E 1 75  ? 72.461  47.127  25.029  1.00 35.78  ? 75  PRO E CA  1 
ATOM   14770 C C   . PRO E 1 75  ? 71.239  46.230  25.216  1.00 37.42  ? 75  PRO E C   1 
ATOM   14771 O O   . PRO E 1 75  ? 71.243  45.092  24.753  1.00 43.00  ? 75  PRO E O   1 
ATOM   14772 C CB  . PRO E 1 75  ? 73.676  46.677  25.832  1.00 35.36  ? 75  PRO E CB  1 
ATOM   14773 C CG  . PRO E 1 75  ? 73.607  47.495  27.098  1.00 35.87  ? 75  PRO E CG  1 
ATOM   14774 C CD  . PRO E 1 75  ? 72.971  48.832  26.716  1.00 37.13  ? 75  PRO E CD  1 
ATOM   14775 N N   . HIS E 1 76  ? 70.185  46.750  25.865  1.00 38.83  ? 76  HIS E N   1 
ATOM   14776 C CA  . HIS E 1 76  ? 68.973  45.975  26.121  1.00 38.75  ? 76  HIS E CA  1 
ATOM   14777 C C   . HIS E 1 76  ? 67.739  46.663  25.513  1.00 35.63  ? 76  HIS E C   1 
ATOM   14778 O O   . HIS E 1 76  ? 66.680  46.731  26.141  1.00 37.97  ? 76  HIS E O   1 
ATOM   14779 C CB  . HIS E 1 76  ? 68.833  45.698  27.630  1.00 38.97  ? 76  HIS E CB  1 
ATOM   14780 C CG  . HIS E 1 76  ? 69.884  44.807  28.216  1.00 37.26  ? 76  HIS E CG  1 
ATOM   14781 N ND1 . HIS E 1 76  ? 70.794  45.248  29.153  1.00 39.32  ? 76  HIS E ND1 1 
ATOM   14782 C CD2 . HIS E 1 76  ? 70.137  43.511  28.036  1.00 37.52  ? 76  HIS E CD2 1 
ATOM   14783 C CE1 . HIS E 1 76  ? 71.591  44.252  29.501  1.00 39.23  ? 76  HIS E CE1 1 
ATOM   14784 N NE2 . HIS E 1 76  ? 71.211  43.193  28.827  1.00 41.65  ? 76  HIS E NE2 1 
ATOM   14785 N N   . LYS E 1 77  ? 67.853  47.124  24.262  1.00 30.37  ? 77  LYS E N   1 
ATOM   14786 C CA  . LYS E 1 77  ? 66.831  47.958  23.656  1.00 30.87  ? 77  LYS E CA  1 
ATOM   14787 C C   . LYS E 1 77  ? 65.546  47.176  23.469  1.00 31.07  ? 77  LYS E C   1 
ATOM   14788 O O   . LYS E 1 77  ? 65.572  46.062  22.940  1.00 29.61  ? 77  LYS E O   1 
ATOM   14789 C CB  . LYS E 1 77  ? 67.173  48.451  22.253  1.00 34.17  ? 77  LYS E CB  1 
ATOM   14790 C CG  . LYS E 1 77  ? 66.252  49.491  21.665  1.00 35.08  ? 77  LYS E CG  1 
ATOM   14791 C CD  . LYS E 1 77  ? 66.743  49.837  20.265  1.00 38.05  ? 77  LYS E CD  1 
ATOM   14792 C CE  . LYS E 1 77  ? 65.812  50.688  19.470  1.00 37.20  ? 77  LYS E CE  1 
ATOM   14793 N NZ  . LYS E 1 77  ? 65.960  52.084  19.873  1.00 37.47  ? 77  LYS E NZ  1 
ATOM   14794 N N   . LEU E 1 78  ? 64.444  47.812  23.907  1.00 32.39  ? 78  LEU E N   1 
ATOM   14795 C CA  . LEU E 1 78  ? 63.096  47.276  23.792  1.00 28.87  ? 78  LEU E CA  1 
ATOM   14796 C C   . LEU E 1 78  ? 62.612  47.356  22.352  1.00 27.04  ? 78  LEU E C   1 
ATOM   14797 O O   . LEU E 1 78  ? 62.976  48.300  21.645  1.00 26.13  ? 78  LEU E O   1 
ATOM   14798 C CB  . LEU E 1 78  ? 62.185  48.086  24.701  1.00 27.72  ? 78  LEU E CB  1 
ATOM   14799 C CG  . LEU E 1 78  ? 62.378  47.848  26.195  1.00 27.44  ? 78  LEU E CG  1 
ATOM   14800 C CD1 . LEU E 1 78  ? 61.504  48.830  26.933  1.00 27.11  ? 78  LEU E CD1 1 
ATOM   14801 C CD2 . LEU E 1 78  ? 62.032  46.425  26.543  1.00 26.83  ? 78  LEU E CD2 1 
ATOM   14802 N N   . PRO E 1 79  ? 61.753  46.396  21.916  1.00 27.53  ? 79  PRO E N   1 
ATOM   14803 C CA  . PRO E 1 79  ? 61.165  46.396  20.569  1.00 27.80  ? 79  PRO E CA  1 
ATOM   14804 C C   . PRO E 1 79  ? 60.453  47.691  20.216  1.00 27.14  ? 79  PRO E C   1 
ATOM   14805 O O   . PRO E 1 79  ? 59.778  48.283  21.055  1.00 25.90  ? 79  PRO E O   1 
ATOM   14806 C CB  . PRO E 1 79  ? 60.171  45.256  20.607  1.00 26.97  ? 79  PRO E CB  1 
ATOM   14807 C CG  . PRO E 1 79  ? 60.768  44.336  21.657  1.00 28.18  ? 79  PRO E CG  1 
ATOM   14808 C CD  . PRO E 1 79  ? 61.269  45.264  22.718  1.00 26.96  ? 79  PRO E CD  1 
ATOM   14809 N N   . THR E 1 80  ? 60.644  48.104  18.961  1.00 29.78  ? 80  THR E N   1 
ATOM   14810 C CA  . THR E 1 80  ? 60.034  49.302  18.409  1.00 31.50  ? 80  THR E CA  1 
ATOM   14811 C C   . THR E 1 80  ? 58.903  48.900  17.470  1.00 30.14  ? 80  THR E C   1 
ATOM   14812 O O   . THR E 1 80  ? 58.813  47.736  17.100  1.00 28.63  ? 80  THR E O   1 
ATOM   14813 C CB  . THR E 1 80  ? 61.115  50.082  17.662  1.00 33.05  ? 80  THR E CB  1 
ATOM   14814 O OG1 . THR E 1 80  ? 61.573  49.230  16.616  1.00 31.29  ? 80  THR E OG1 1 
ATOM   14815 C CG2 . THR E 1 80  ? 62.266  50.476  18.573  1.00 35.04  ? 80  THR E CG2 1 
ATOM   14816 N N   . ALA E 1 81  ? 58.103  49.881  17.022  1.00 32.13  ? 81  ALA E N   1 
ATOM   14817 C CA  . ALA E 1 81  ? 57.261  49.676  15.850  1.00 31.78  ? 81  ALA E CA  1 
ATOM   14818 C C   . ALA E 1 81  ? 58.166  49.398  14.655  1.00 34.48  ? 81  ALA E C   1 
ATOM   14819 O O   . ALA E 1 81  ? 59.336  49.816  14.660  1.00 36.70  ? 81  ALA E O   1 
ATOM   14820 C CB  . ALA E 1 81  ? 56.382  50.870  15.601  1.00 32.32  ? 81  ALA E CB  1 
ATOM   14821 N N   . GLU E 1 82  ? 57.621  48.683  13.658  1.00 35.57  ? 82  GLU E N   1 
ATOM   14822 C CA  . GLU E 1 82  ? 58.298  48.491  12.385  1.00 38.35  ? 82  GLU E CA  1 
ATOM   14823 C C   . GLU E 1 82  ? 58.632  49.862  11.776  1.00 35.10  ? 82  GLU E C   1 
ATOM   14824 O O   . GLU E 1 82  ? 57.757  50.677  11.533  1.00 32.10  ? 82  GLU E O   1 
ATOM   14825 C CB  . GLU E 1 82  ? 57.461  47.655  11.422  1.00 43.83  ? 82  GLU E CB  1 
ATOM   14826 C CG  . GLU E 1 82  ? 58.318  46.767  10.523  1.00 59.64  ? 82  GLU E CG  1 
ATOM   14827 C CD  . GLU E 1 82  ? 57.661  46.342  9.217   1.00 79.99  ? 82  GLU E CD  1 
ATOM   14828 O OE1 . GLU E 1 82  ? 58.223  46.698  8.148   1.00 92.18  ? 82  GLU E OE1 1 
ATOM   14829 O OE2 . GLU E 1 82  ? 56.597  45.669  9.249   1.00 84.19  ? 82  GLU E OE2 1 
ATOM   14830 N N   . GLY E 1 83  ? 59.922  50.141  11.569  1.00 30.50  ? 83  GLY E N   1 
ATOM   14831 C CA  . GLY E 1 83  ? 60.347  51.398  10.987  1.00 28.40  ? 83  GLY E CA  1 
ATOM   14832 C C   . GLY E 1 83  ? 60.699  52.399  12.073  1.00 30.15  ? 83  GLY E C   1 
ATOM   14833 O O   . GLY E 1 83  ? 61.175  53.476  11.761  1.00 27.74  ? 83  GLY E O   1 
ATOM   14834 N N   . GLY E 1 84  ? 60.451  52.044  13.349  1.00 33.80  ? 84  GLY E N   1 
ATOM   14835 C CA  . GLY E 1 84  ? 60.504  53.014  14.440  1.00 33.08  ? 84  GLY E CA  1 
ATOM   14836 C C   . GLY E 1 84  ? 61.794  52.949  15.260  1.00 31.91  ? 84  GLY E C   1 
ATOM   14837 O O   . GLY E 1 84  ? 62.576  52.002  15.163  1.00 28.45  ? 84  GLY E O   1 
ATOM   14838 N N   . PHE E 1 85  ? 61.985  53.971  16.095  1.00 33.46  ? 85  PHE E N   1 
ATOM   14839 C CA  . PHE E 1 85  ? 63.147  54.046  16.968  1.00 38.44  ? 85  PHE E CA  1 
ATOM   14840 C C   . PHE E 1 85  ? 62.713  53.957  18.438  1.00 32.56  ? 85  PHE E C   1 
ATOM   14841 O O   . PHE E 1 85  ? 63.399  53.322  19.245  1.00 30.25  ? 85  PHE E O   1 
ATOM   14842 C CB  . PHE E 1 85  ? 64.009  55.295  16.704  1.00 41.92  ? 85  PHE E CB  1 
ATOM   14843 C CG  . PHE E 1 85  ? 65.177  55.394  17.680  1.00 51.53  ? 85  PHE E CG  1 
ATOM   14844 C CD1 . PHE E 1 85  ? 66.300  54.580  17.540  1.00 56.71  ? 85  PHE E CD1 1 
ATOM   14845 C CD2 . PHE E 1 85  ? 65.129  56.252  18.780  1.00 62.76  ? 85  PHE E CD2 1 
ATOM   14846 C CE1 . PHE E 1 85  ? 67.350  54.643  18.456  1.00 60.17  ? 85  PHE E CE1 1 
ATOM   14847 C CE2 . PHE E 1 85  ? 66.184  56.316  19.689  1.00 58.68  ? 85  PHE E CE2 1 
ATOM   14848 C CZ  . PHE E 1 85  ? 67.293  55.516  19.521  1.00 57.20  ? 85  PHE E CZ  1 
ATOM   14849 N N   . GLU E 1 86  ? 61.607  54.629  18.786  1.00 29.62  ? 86  GLU E N   1 
ATOM   14850 C CA  . GLU E 1 86  ? 61.216  54.794  20.174  1.00 28.67  ? 86  GLU E CA  1 
ATOM   14851 C C   . GLU E 1 86  ? 60.673  53.478  20.716  1.00 29.19  ? 86  GLU E C   1 
ATOM   14852 O O   . GLU E 1 86  ? 60.024  52.725  19.985  1.00 32.61  ? 86  GLU E O   1 
ATOM   14853 C CB  . GLU E 1 86  ? 60.252  55.964  20.380  1.00 28.36  ? 86  GLU E CB  1 
ATOM   14854 C CG  . GLU E 1 86  ? 60.875  57.318  20.050  1.00 28.58  ? 86  GLU E CG  1 
ATOM   14855 C CD  . GLU E 1 86  ? 62.137  57.645  20.830  1.00 27.72  ? 86  GLU E CD  1 
ATOM   14856 O OE1 . GLU E 1 86  ? 62.862  58.567  20.426  1.00 26.68  ? 86  GLU E OE1 1 
ATOM   14857 O OE2 . GLU E 1 86  ? 62.370  57.007  21.874  1.00 25.11  ? 86  GLU E OE2 1 
ATOM   14858 N N   . PRO E 1 87  ? 60.968  53.150  22.006  1.00 28.83  ? 87  PRO E N   1 
ATOM   14859 C CA  . PRO E 1 87  ? 60.469  51.919  22.633  1.00 28.51  ? 87  PRO E CA  1 
ATOM   14860 C C   . PRO E 1 87  ? 58.954  51.884  22.836  1.00 29.55  ? 87  PRO E C   1 
ATOM   14861 O O   . PRO E 1 87  ? 58.342  52.891  23.205  1.00 29.40  ? 87  PRO E O   1 
ATOM   14862 C CB  . PRO E 1 87  ? 61.235  51.836  23.968  1.00 29.23  ? 87  PRO E CB  1 
ATOM   14863 C CG  . PRO E 1 87  ? 61.612  53.272  24.274  1.00 28.93  ? 87  PRO E CG  1 
ATOM   14864 C CD  . PRO E 1 87  ? 61.820  53.936  22.912  1.00 27.46  ? 87  PRO E CD  1 
ATOM   14865 N N   . LEU E 1 88  ? 58.372  50.704  22.567  1.00 29.73  ? 88  LEU E N   1 
ATOM   14866 C CA  . LEU E 1 88  ? 56.955  50.468  22.742  1.00 28.59  ? 88  LEU E CA  1 
ATOM   14867 C C   . LEU E 1 88  ? 56.652  50.229  24.226  1.00 30.78  ? 88  LEU E C   1 
ATOM   14868 O O   . LEU E 1 88  ? 57.217  49.331  24.869  1.00 29.98  ? 88  LEU E O   1 
ATOM   14869 C CB  . LEU E 1 88  ? 56.514  49.291  21.866  1.00 28.51  ? 88  LEU E CB  1 
ATOM   14870 C CG  . LEU E 1 88  ? 56.534  49.508  20.342  1.00 27.97  ? 88  LEU E CG  1 
ATOM   14871 C CD1 . LEU E 1 88  ? 55.780  48.400  19.628  1.00 29.42  ? 88  LEU E CD1 1 
ATOM   14872 C CD2 . LEU E 1 88  ? 55.961  50.821  19.882  1.00 26.94  ? 88  LEU E CD2 1 
ATOM   14873 N N   . PRO E 1 89  ? 55.681  50.985  24.795  1.00 31.86  ? 89  PRO E N   1 
ATOM   14874 C CA  . PRO E 1 89  ? 55.154  50.706  26.132  1.00 30.34  ? 89  PRO E CA  1 
ATOM   14875 C C   . PRO E 1 89  ? 54.705  49.262  26.293  1.00 29.23  ? 89  PRO E C   1 
ATOM   14876 O O   . PRO E 1 89  ? 54.826  48.702  27.373  1.00 29.29  ? 89  PRO E O   1 
ATOM   14877 C CB  . PRO E 1 89  ? 53.982  51.695  26.303  1.00 30.60  ? 89  PRO E CB  1 
ATOM   14878 C CG  . PRO E 1 89  ? 53.713  52.214  24.925  1.00 28.89  ? 89  PRO E CG  1 
ATOM   14879 C CD  . PRO E 1 89  ? 55.033  52.156  24.177  1.00 30.99  ? 89  PRO E CD  1 
ATOM   14880 N N   . GLU E 1 90  ? 54.216  48.650  25.213  1.00 28.14  ? 90  GLU E N   1 
ATOM   14881 C CA  . GLU E 1 90  ? 53.737  47.281  25.285  1.00 28.21  ? 90  GLU E CA  1 
ATOM   14882 C C   . GLU E 1 90  ? 54.820  46.368  25.851  1.00 27.68  ? 90  GLU E C   1 
ATOM   14883 O O   . GLU E 1 90  ? 54.486  45.491  26.635  1.00 24.77  ? 90  GLU E O   1 
ATOM   14884 C CB  . GLU E 1 90  ? 53.223  46.720  23.952  1.00 28.54  ? 90  GLU E CB  1 
ATOM   14885 C CG  . GLU E 1 90  ? 51.881  47.312  23.529  1.00 25.39  ? 90  GLU E CG  1 
ATOM   14886 C CD  . GLU E 1 90  ? 51.982  48.492  22.591  1.00 23.21  ? 90  GLU E CD  1 
ATOM   14887 O OE1 . GLU E 1 90  ? 51.198  48.455  21.635  1.00 21.90  ? 90  GLU E OE1 1 
ATOM   14888 O OE2 . GLU E 1 90  ? 52.809  49.414  22.753  1.00 23.02  ? 90  GLU E OE2 1 
ATOM   14889 N N   . GLY E 1 91  ? 56.091  46.578  25.450  1.00 28.91  ? 91  GLY E N   1 
ATOM   14890 C CA  . GLY E 1 91  ? 57.212  45.764  25.919  1.00 25.54  ? 91  GLY E CA  1 
ATOM   14891 C C   . GLY E 1 91  ? 57.702  46.208  27.297  1.00 25.71  ? 91  GLY E C   1 
ATOM   14892 O O   . GLY E 1 91  ? 58.078  45.378  28.133  1.00 23.75  ? 91  GLY E O   1 
ATOM   14893 N N   . LEU E 1 92  ? 57.685  47.525  27.536  1.00 23.73  ? 92  LEU E N   1 
ATOM   14894 C CA  . LEU E 1 92  ? 57.983  48.024  28.862  1.00 24.84  ? 92  LEU E CA  1 
ATOM   14895 C C   . LEU E 1 92  ? 57.031  47.375  29.872  1.00 25.64  ? 92  LEU E C   1 
ATOM   14896 O O   . LEU E 1 92  ? 57.457  46.946  30.929  1.00 25.82  ? 92  LEU E O   1 
ATOM   14897 C CB  . LEU E 1 92  ? 57.919  49.545  28.952  1.00 25.12  ? 92  LEU E CB  1 
ATOM   14898 C CG  . LEU E 1 92  ? 57.989  50.078  30.385  1.00 28.41  ? 92  LEU E CG  1 
ATOM   14899 C CD1 . LEU E 1 92  ? 59.294  49.692  31.056  1.00 28.04  ? 92  LEU E CD1 1 
ATOM   14900 C CD2 . LEU E 1 92  ? 57.837  51.573  30.445  1.00 32.49  ? 92  LEU E CD2 1 
ATOM   14901 N N   . TRP E 1 93  ? 55.735  47.317  29.547  1.00 25.99  ? 93  TRP E N   1 
ATOM   14902 C CA  . TRP E 1 93  ? 54.735  46.706  30.412  1.00 27.34  ? 93  TRP E CA  1 
ATOM   14903 C C   . TRP E 1 93  ? 55.087  45.248  30.729  1.00 26.35  ? 93  TRP E C   1 
ATOM   14904 O O   . TRP E 1 93  ? 54.997  44.851  31.887  1.00 26.19  ? 93  TRP E O   1 
ATOM   14905 C CB  . TRP E 1 93  ? 53.342  46.800  29.765  1.00 27.83  ? 93  TRP E CB  1 
ATOM   14906 C CG  . TRP E 1 93  ? 52.192  46.610  30.718  1.00 27.23  ? 93  TRP E CG  1 
ATOM   14907 C CD1 . TRP E 1 93  ? 51.909  47.341  31.832  1.00 28.09  ? 93  TRP E CD1 1 
ATOM   14908 C CD2 . TRP E 1 93  ? 51.172  45.598  30.635  1.00 28.54  ? 93  TRP E CD2 1 
ATOM   14909 N NE1 . TRP E 1 93  ? 50.792  46.849  32.449  1.00 28.80  ? 93  TRP E NE1 1 
ATOM   14910 C CE2 . TRP E 1 93  ? 50.317  45.787  31.734  1.00 28.08  ? 93  TRP E CE2 1 
ATOM   14911 C CE3 . TRP E 1 93  ? 50.899  44.564  29.743  1.00 28.89  ? 93  TRP E CE3 1 
ATOM   14912 C CZ2 . TRP E 1 93  ? 49.213  44.985  31.953  1.00 27.99  ? 93  TRP E CZ2 1 
ATOM   14913 C CZ3 . TRP E 1 93  ? 49.797  43.776  29.960  1.00 28.70  ? 93  TRP E CZ3 1 
ATOM   14914 C CH2 . TRP E 1 93  ? 48.972  43.983  31.050  1.00 29.53  ? 93  TRP E CH2 1 
ATOM   14915 N N   . TYR E 1 94  ? 55.473  44.475  29.698  1.00 25.27  ? 94  TYR E N   1 
ATOM   14916 C CA  . TYR E 1 94  ? 55.919  43.090  29.837  1.00 29.05  ? 94  TYR E CA  1 
ATOM   14917 C C   . TYR E 1 94  ? 57.041  42.991  30.872  1.00 27.18  ? 94  TYR E C   1 
ATOM   14918 O O   . TYR E 1 94  ? 57.044  42.083  31.699  1.00 26.71  ? 94  TYR E O   1 
ATOM   14919 C CB  . TYR E 1 94  ? 56.439  42.493  28.519  1.00 30.23  ? 94  TYR E CB  1 
ATOM   14920 C CG  . TYR E 1 94  ? 56.798  41.011  28.593  1.00 30.12  ? 94  TYR E CG  1 
ATOM   14921 C CD1 . TYR E 1 94  ? 58.027  40.594  29.080  1.00 30.94  ? 94  TYR E CD1 1 
ATOM   14922 C CD2 . TYR E 1 94  ? 55.917  40.029  28.169  1.00 30.23  ? 94  TYR E CD2 1 
ATOM   14923 C CE1 . TYR E 1 94  ? 58.368  39.252  29.153  1.00 30.44  ? 94  TYR E CE1 1 
ATOM   14924 C CE2 . TYR E 1 94  ? 56.237  38.680  28.242  1.00 31.70  ? 94  TYR E CE2 1 
ATOM   14925 C CZ  . TYR E 1 94  ? 57.476  38.285  28.721  1.00 34.28  ? 94  TYR E CZ  1 
ATOM   14926 O OH  . TYR E 1 94  ? 57.840  36.958  28.774  1.00 31.70  ? 94  TYR E OH  1 
ATOM   14927 N N   . LEU E 1 95  ? 57.973  43.946  30.811  1.00 26.74  ? 95  LEU E N   1 
ATOM   14928 C CA  . LEU E 1 95  ? 59.135  43.977  31.679  1.00 27.52  ? 95  LEU E CA  1 
ATOM   14929 C C   . LEU E 1 95  ? 58.713  44.289  33.114  1.00 28.69  ? 95  LEU E C   1 
ATOM   14930 O O   . LEU E 1 95  ? 59.213  43.647  34.037  1.00 29.59  ? 95  LEU E O   1 
ATOM   14931 C CB  . LEU E 1 95  ? 60.139  44.996  31.134  1.00 28.16  ? 95  LEU E CB  1 
ATOM   14932 C CG  . LEU E 1 95  ? 61.304  45.378  32.058  1.00 28.31  ? 95  LEU E CG  1 
ATOM   14933 C CD1 . LEU E 1 95  ? 62.217  44.188  32.332  1.00 31.06  ? 95  LEU E CD1 1 
ATOM   14934 C CD2 . LEU E 1 95  ? 62.070  46.539  31.488  1.00 27.75  ? 95  LEU E CD2 1 
ATOM   14935 N N   . LEU E 1 96  ? 57.809  45.269  33.294  1.00 27.97  ? 96  LEU E N   1 
ATOM   14936 C CA  . LEU E 1 96  ? 57.363  45.679  34.622  1.00 28.95  ? 96  LEU E CA  1 
ATOM   14937 C C   . LEU E 1 96  ? 56.710  44.498  35.328  1.00 27.91  ? 96  LEU E C   1 
ATOM   14938 O O   . LEU E 1 96  ? 56.897  44.317  36.517  1.00 28.27  ? 96  LEU E O   1 
ATOM   14939 C CB  . LEU E 1 96  ? 56.387  46.854  34.599  1.00 27.31  ? 96  LEU E CB  1 
ATOM   14940 C CG  . LEU E 1 96  ? 56.924  48.185  34.083  1.00 25.66  ? 96  LEU E CG  1 
ATOM   14941 C CD1 . LEU E 1 96  ? 55.906  49.275  34.336  1.00 27.62  ? 96  LEU E CD1 1 
ATOM   14942 C CD2 . LEU E 1 96  ? 58.217  48.557  34.732  1.00 25.44  ? 96  LEU E CD2 1 
ATOM   14943 N N   . LEU E 1 97  ? 55.929  43.717  34.583  1.00 25.19  ? 97  LEU E N   1 
ATOM   14944 C CA  . LEU E 1 97  ? 55.257  42.574  35.148  1.00 25.55  ? 97  LEU E CA  1 
ATOM   14945 C C   . LEU E 1 97  ? 56.206  41.409  35.422  1.00 25.63  ? 97  LEU E C   1 
ATOM   14946 O O   . LEU E 1 97  ? 56.115  40.826  36.485  1.00 27.84  ? 97  LEU E O   1 
ATOM   14947 C CB  . LEU E 1 97  ? 54.111  42.201  34.215  1.00 28.45  ? 97  LEU E CB  1 
ATOM   14948 C CG  . LEU E 1 97  ? 52.837  43.039  34.372  1.00 31.48  ? 97  LEU E CG  1 
ATOM   14949 C CD1 . LEU E 1 97  ? 51.873  42.778  33.229  1.00 33.55  ? 97  LEU E CD1 1 
ATOM   14950 C CD2 . LEU E 1 97  ? 52.164  42.748  35.712  1.00 33.54  ? 97  LEU E CD2 1 
ATOM   14951 N N   . THR E 1 98  ? 57.076  41.022  34.482  1.00 27.72  ? 98  THR E N   1 
ATOM   14952 C CA  . THR E 1 98  ? 57.827  39.778  34.633  1.00 28.46  ? 98  THR E CA  1 
ATOM   14953 C C   . THR E 1 98  ? 59.229  40.021  35.190  1.00 29.11  ? 98  THR E C   1 
ATOM   14954 O O   . THR E 1 98  ? 59.868  39.083  35.648  1.00 35.05  ? 98  THR E O   1 
ATOM   14955 C CB  . THR E 1 98  ? 57.950  39.042  33.300  1.00 28.42  ? 98  THR E CB  1 
ATOM   14956 O OG1 . THR E 1 98  ? 58.664  39.937  32.458  1.00 25.83  ? 98  THR E OG1 1 
ATOM   14957 C CG2 . THR E 1 98  ? 56.602  38.691  32.712  1.00 31.47  ? 98  THR E CG2 1 
ATOM   14958 N N   . GLY E 1 99  ? 59.745  41.245  35.077  1.00 30.27  ? 99  GLY E N   1 
ATOM   14959 C CA  . GLY E 1 99  ? 61.126  41.535  35.416  1.00 28.14  ? 99  GLY E CA  1 
ATOM   14960 C C   . GLY E 1 99  ? 62.099  41.050  34.353  1.00 30.08  ? 99  GLY E C   1 
ATOM   14961 O O   . GLY E 1 99  ? 63.296  41.211  34.528  1.00 35.02  ? 99  GLY E O   1 
ATOM   14962 N N   . GLU E 1 100 ? 61.575  40.535  33.229  1.00 33.83  ? 100 GLU E N   1 
ATOM   14963 C CA  . GLU E 1 100 ? 62.366  40.016  32.119  1.00 31.42  ? 100 GLU E CA  1 
ATOM   14964 C C   . GLU E 1 100 ? 62.095  40.798  30.830  1.00 32.60  ? 100 GLU E C   1 
ATOM   14965 O O   . GLU E 1 100 ? 61.023  41.371  30.650  1.00 36.20  ? 100 GLU E O   1 
ATOM   14966 C CB  . GLU E 1 100 ? 61.977  38.556  31.906  1.00 32.29  ? 100 GLU E CB  1 
ATOM   14967 C CG  . GLU E 1 100 ? 62.320  37.644  33.086  1.00 33.28  ? 100 GLU E CG  1 
ATOM   14968 C CD  . GLU E 1 100 ? 61.683  36.267  32.960  1.00 35.32  ? 100 GLU E CD  1 
ATOM   14969 O OE1 . GLU E 1 100 ? 61.972  35.329  33.730  1.00 34.46  ? 100 GLU E OE1 1 
ATOM   14970 O OE2 . GLU E 1 100 ? 60.848  36.145  32.048  1.00 37.75  ? 100 GLU E OE2 1 
ATOM   14971 N N   . LEU E 1 101 ? 63.067  40.785  29.909  1.00 31.71  ? 101 LEU E N   1 
ATOM   14972 C CA  . LEU E 1 101 ? 63.015  41.580  28.688  1.00 28.04  ? 101 LEU E CA  1 
ATOM   14973 C C   . LEU E 1 101 ? 62.180  40.836  27.650  1.00 26.99  ? 101 LEU E C   1 
ATOM   14974 O O   . LEU E 1 101 ? 62.321  39.631  27.491  1.00 27.27  ? 101 LEU E O   1 
ATOM   14975 C CB  . LEU E 1 101 ? 64.411  41.915  28.154  1.00 25.65  ? 101 LEU E CB  1 
ATOM   14976 C CG  . LEU E 1 101 ? 65.295  42.770  29.067  1.00 28.17  ? 101 LEU E CG  1 
ATOM   14977 C CD1 . LEU E 1 101 ? 66.770  42.647  28.670  1.00 30.11  ? 101 LEU E CD1 1 
ATOM   14978 C CD2 . LEU E 1 101 ? 64.879  44.252  29.094  1.00 27.33  ? 101 LEU E CD2 1 
ATOM   14979 N N   . PRO E 1 102 ? 61.254  41.516  26.938  1.00 29.66  ? 102 PRO E N   1 
ATOM   14980 C CA  . PRO E 1 102 ? 60.414  40.831  25.954  1.00 31.27  ? 102 PRO E CA  1 
ATOM   14981 C C   . PRO E 1 102 ? 61.184  40.504  24.678  1.00 31.40  ? 102 PRO E C   1 
ATOM   14982 O O   . PRO E 1 102 ? 62.149  41.209  24.378  1.00 33.79  ? 102 PRO E O   1 
ATOM   14983 C CB  . PRO E 1 102 ? 59.267  41.846  25.723  1.00 30.62  ? 102 PRO E CB  1 
ATOM   14984 C CG  . PRO E 1 102 ? 59.886  43.198  26.002  1.00 31.21  ? 102 PRO E CG  1 
ATOM   14985 C CD  . PRO E 1 102 ? 60.924  42.955  27.084  1.00 30.20  ? 102 PRO E CD  1 
ATOM   14986 N N   . THR E 1 103 ? 60.736  39.445  23.970  1.00 30.09  ? 103 THR E N   1 
ATOM   14987 C CA  . THR E 1 103 ? 61.068  39.206  22.569  1.00 29.00  ? 103 THR E CA  1 
ATOM   14988 C C   . THR E 1 103 ? 60.117  39.997  21.665  1.00 33.90  ? 103 THR E C   1 
ATOM   14989 O O   . THR E 1 103 ? 59.086  40.511  22.116  1.00 35.30  ? 103 THR E O   1 
ATOM   14990 C CB  . THR E 1 103 ? 60.980  37.717  22.217  1.00 28.17  ? 103 THR E CB  1 
ATOM   14991 O OG1 . THR E 1 103 ? 59.611  37.347  22.251  1.00 23.86  ? 103 THR E OG1 1 
ATOM   14992 C CG2 . THR E 1 103 ? 61.758  36.823  23.168  1.00 30.04  ? 103 THR E CG2 1 
ATOM   14993 N N   . GLU E 1 104 ? 60.439  40.053  20.364  1.00 34.80  ? 104 GLU E N   1 
ATOM   14994 C CA  . GLU E 1 104 ? 59.573  40.718  19.401  1.00 34.96  ? 104 GLU E CA  1 
ATOM   14995 C C   . GLU E 1 104 ? 58.191  40.065  19.431  1.00 34.10  ? 104 GLU E C   1 
ATOM   14996 O O   . GLU E 1 104 ? 57.181  40.756  19.454  1.00 27.71  ? 104 GLU E O   1 
ATOM   14997 C CB  . GLU E 1 104 ? 60.228  40.703  18.024  1.00 35.87  ? 104 GLU E CB  1 
ATOM   14998 C CG  . GLU E 1 104 ? 61.488  41.570  17.961  1.00 35.91  ? 104 GLU E CG  1 
ATOM   14999 C CD  . GLU E 1 104 ? 61.278  43.070  17.728  1.00 39.59  ? 104 GLU E CD  1 
ATOM   15000 O OE1 . GLU E 1 104 ? 62.275  43.819  17.805  1.00 42.53  ? 104 GLU E OE1 1 
ATOM   15001 O OE2 . GLU E 1 104 ? 60.145  43.528  17.476  1.00 36.69  ? 104 GLU E OE2 1 
ATOM   15002 N N   . GLU E 1 105 ? 58.152  38.732  19.502  1.00 39.31  ? 105 GLU E N   1 
ATOM   15003 C CA  . GLU E 1 105 ? 56.882  38.033  19.629  1.00 44.56  ? 105 GLU E CA  1 
ATOM   15004 C C   . GLU E 1 105 ? 56.109  38.511  20.862  1.00 41.32  ? 105 GLU E C   1 
ATOM   15005 O O   . GLU E 1 105 ? 54.908  38.759  20.727  1.00 42.30  ? 105 GLU E O   1 
ATOM   15006 C CB  . GLU E 1 105 ? 56.946  36.497  19.584  1.00 53.97  ? 105 GLU E CB  1 
ATOM   15007 C CG  . GLU E 1 105 ? 56.494  35.905  18.242  1.00 71.97  ? 105 GLU E CG  1 
ATOM   15008 C CD  . GLU E 1 105 ? 55.176  36.412  17.619  1.00 83.71  ? 105 GLU E CD  1 
ATOM   15009 O OE1 . GLU E 1 105 ? 55.250  37.057  16.540  1.00 73.64  ? 105 GLU E OE1 1 
ATOM   15010 O OE2 . GLU E 1 105 ? 54.066  36.177  18.176  1.00 85.11  ? 105 GLU E OE2 1 
ATOM   15011 N N   . ASP E 1 106 ? 56.768  38.641  22.036  1.00 34.02  ? 106 ASP E N   1 
ATOM   15012 C CA  . ASP E 1 106 ? 56.063  38.982  23.266  1.00 33.66  ? 106 ASP E CA  1 
ATOM   15013 C C   . ASP E 1 106 ? 55.320  40.309  23.099  1.00 34.32  ? 106 ASP E C   1 
ATOM   15014 O O   . ASP E 1 106 ? 54.157  40.422  23.493  1.00 31.64  ? 106 ASP E O   1 
ATOM   15015 C CB  . ASP E 1 106 ? 56.938  38.982  24.511  1.00 36.74  ? 106 ASP E CB  1 
ATOM   15016 C CG  . ASP E 1 106 ? 57.627  37.674  24.894  1.00 39.99  ? 106 ASP E CG  1 
ATOM   15017 O OD1 . ASP E 1 106 ? 57.149  36.576  24.498  1.00 36.17  ? 106 ASP E OD1 1 
ATOM   15018 O OD2 . ASP E 1 106 ? 58.697  37.775  25.522  1.00 40.31  ? 106 ASP E OD2 1 
ATOM   15019 N N   . VAL E 1 107 ? 55.961  41.282  22.445  1.00 33.01  ? 107 VAL E N   1 
ATOM   15020 C CA  . VAL E 1 107 ? 55.392  42.613  22.327  1.00 33.26  ? 107 VAL E CA  1 
ATOM   15021 C C   . VAL E 1 107 ? 54.190  42.578  21.397  1.00 34.65  ? 107 VAL E C   1 
ATOM   15022 O O   . VAL E 1 107 ? 53.219  43.297  21.623  1.00 31.60  ? 107 VAL E O   1 
ATOM   15023 C CB  . VAL E 1 107 ? 56.414  43.667  21.872  1.00 30.74  ? 107 VAL E CB  1 
ATOM   15024 C CG1 . VAL E 1 107 ? 55.784  45.010  21.551  1.00 29.40  ? 107 VAL E CG1 1 
ATOM   15025 C CG2 . VAL E 1 107 ? 57.484  43.869  22.926  1.00 33.52  ? 107 VAL E CG2 1 
ATOM   15026 N N   . LYS E 1 108 ? 54.260  41.727  20.377  1.00 39.27  ? 108 LYS E N   1 
ATOM   15027 C CA  . LYS E 1 108 ? 53.205  41.674  19.382  1.00 46.28  ? 108 LYS E CA  1 
ATOM   15028 C C   . LYS E 1 108 ? 51.957  41.036  19.997  1.00 41.53  ? 108 LYS E C   1 
ATOM   15029 O O   . LYS E 1 108 ? 50.834  41.407  19.641  1.00 36.94  ? 108 LYS E O   1 
ATOM   15030 C CB  . LYS E 1 108 ? 53.687  40.980  18.099  1.00 54.24  ? 108 LYS E CB  1 
ATOM   15031 C CG  . LYS E 1 108 ? 54.520  41.863  17.140  1.00 63.73  ? 108 LYS E CG  1 
ATOM   15032 C CD  . LYS E 1 108 ? 54.381  41.473  15.662  1.00 70.41  ? 108 LYS E CD  1 
ATOM   15033 C CE  . LYS E 1 108 ? 55.551  41.789  14.775  1.00 66.49  ? 108 LYS E CE  1 
ATOM   15034 N NZ  . LYS E 1 108 ? 56.676  40.869  14.981  1.00 63.50  ? 108 LYS E NZ  1 
ATOM   15035 N N   . GLU E 1 109 ? 52.164  40.077  20.911  1.00 36.28  ? 109 GLU E N   1 
ATOM   15036 C CA  . GLU E 1 109 ? 51.053  39.440  21.602  1.00 39.94  ? 109 GLU E CA  1 
ATOM   15037 C C   . GLU E 1 109 ? 50.278  40.473  22.426  1.00 37.36  ? 109 GLU E C   1 
ATOM   15038 O O   . GLU E 1 109 ? 49.054  40.425  22.471  1.00 35.38  ? 109 GLU E O   1 
ATOM   15039 C CB  . GLU E 1 109 ? 51.516  38.293  22.506  1.00 44.01  ? 109 GLU E CB  1 
ATOM   15040 C CG  . GLU E 1 109 ? 51.745  36.969  21.776  1.00 45.39  ? 109 GLU E CG  1 
ATOM   15041 C CD  . GLU E 1 109 ? 52.122  35.813  22.689  1.00 45.62  ? 109 GLU E CD  1 
ATOM   15042 O OE1 . GLU E 1 109 ? 52.156  34.665  22.181  1.00 45.17  ? 109 GLU E OE1 1 
ATOM   15043 O OE2 . GLU E 1 109 ? 52.372  36.064  23.904  1.00 40.57  ? 109 GLU E OE2 1 
ATOM   15044 N N   . ILE E 1 110 ? 51.008  41.402  23.065  1.00 33.16  ? 110 ILE E N   1 
ATOM   15045 C CA  . ILE E 1 110 ? 50.425  42.416  23.927  1.00 31.13  ? 110 ILE E CA  1 
ATOM   15046 C C   . ILE E 1 110 ? 49.742  43.469  23.069  1.00 29.47  ? 110 ILE E C   1 
ATOM   15047 O O   . ILE E 1 110 ? 48.581  43.772  23.291  1.00 25.51  ? 110 ILE E O   1 
ATOM   15048 C CB  . ILE E 1 110 ? 51.483  43.047  24.840  1.00 30.83  ? 110 ILE E CB  1 
ATOM   15049 C CG1 . ILE E 1 110 ? 51.926  42.062  25.879  1.00 32.34  ? 110 ILE E CG1 1 
ATOM   15050 C CG2 . ILE E 1 110 ? 50.981  44.359  25.465  1.00 30.77  ? 110 ILE E CG2 1 
ATOM   15051 C CD1 . ILE E 1 110 ? 53.189  42.498  26.595  1.00 37.88  ? 110 ILE E CD1 1 
ATOM   15052 N N   . SER E 1 111 ? 50.482  44.020  22.095  1.00 33.25  ? 111 SER E N   1 
ATOM   15053 C CA  . SER E 1 111 ? 49.888  44.866  21.066  1.00 31.97  ? 111 SER E CA  1 
ATOM   15054 C C   . SER E 1 111 ? 48.584  44.267  20.529  1.00 28.55  ? 111 SER E C   1 
ATOM   15055 O O   . SER E 1 111 ? 47.627  45.001  20.396  1.00 31.35  ? 111 SER E O   1 
ATOM   15056 C CB  . SER E 1 111 ? 50.847  45.165  19.949  1.00 30.32  ? 111 SER E CB  1 
ATOM   15057 O OG  . SER E 1 111 ? 51.725  46.201  20.345  1.00 34.36  ? 111 SER E OG  1 
ATOM   15058 N N   . ALA E 1 112 ? 48.548  42.963  20.230  1.00 27.07  ? 112 ALA E N   1 
ATOM   15059 C CA  . ALA E 1 112 ? 47.388  42.319  19.620  1.00 29.35  ? 112 ALA E CA  1 
ATOM   15060 C C   . ALA E 1 112 ? 46.234  42.200  20.612  1.00 33.58  ? 112 ALA E C   1 
ATOM   15061 O O   . ALA E 1 112 ? 45.077  42.236  20.226  1.00 38.10  ? 112 ALA E O   1 
ATOM   15062 C CB  . ALA E 1 112 ? 47.751  40.942  19.124  1.00 28.67  ? 112 ALA E CB  1 
ATOM   15063 N N   . GLU E 1 113 ? 46.558  42.048  21.893  1.00 35.24  ? 113 GLU E N   1 
ATOM   15064 C CA  . GLU E 1 113 ? 45.553  41.927  22.928  1.00 34.96  ? 113 GLU E CA  1 
ATOM   15065 C C   . GLU E 1 113 ? 44.924  43.302  23.177  1.00 34.49  ? 113 GLU E C   1 
ATOM   15066 O O   . GLU E 1 113 ? 43.703  43.455  23.189  1.00 37.66  ? 113 GLU E O   1 
ATOM   15067 C CB  . GLU E 1 113 ? 46.320  41.248  24.052  1.00 37.99  ? 113 GLU E CB  1 
ATOM   15068 C CG  . GLU E 1 113 ? 45.431  40.469  24.998  1.00 41.78  ? 113 GLU E CG  1 
ATOM   15069 C CD  . GLU E 1 113 ? 44.779  39.308  24.307  1.00 39.72  ? 113 GLU E CD  1 
ATOM   15070 O OE1 . GLU E 1 113 ? 43.630  39.476  23.838  1.00 41.73  ? 113 GLU E OE1 1 
ATOM   15071 O OE2 . GLU E 1 113 ? 45.426  38.248  24.296  1.00 37.77  ? 113 GLU E OE2 1 
ATOM   15072 N N   . PHE E 1 114 ? 45.750  44.341  23.250  1.00 33.65  ? 114 PHE E N   1 
ATOM   15073 C CA  . PHE E 1 114 ? 45.237  45.697  23.372  1.00 35.44  ? 114 PHE E CA  1 
ATOM   15074 C C   . PHE E 1 114 ? 44.386  46.123  22.176  1.00 39.97  ? 114 PHE E C   1 
ATOM   15075 O O   . PHE E 1 114 ? 43.537  46.982  22.353  1.00 48.86  ? 114 PHE E O   1 
ATOM   15076 C CB  . PHE E 1 114 ? 46.367  46.714  23.522  1.00 35.11  ? 114 PHE E CB  1 
ATOM   15077 C CG  . PHE E 1 114 ? 47.125  46.648  24.840  1.00 35.50  ? 114 PHE E CG  1 
ATOM   15078 C CD1 . PHE E 1 114 ? 46.702  45.828  25.884  1.00 35.17  ? 114 PHE E CD1 1 
ATOM   15079 C CD2 . PHE E 1 114 ? 48.213  47.482  25.058  1.00 36.17  ? 114 PHE E CD2 1 
ATOM   15080 C CE1 . PHE E 1 114 ? 47.394  45.793  27.082  1.00 35.29  ? 114 PHE E CE1 1 
ATOM   15081 C CE2 . PHE E 1 114 ? 48.895  47.447  26.263  1.00 36.31  ? 114 PHE E CE2 1 
ATOM   15082 C CZ  . PHE E 1 114 ? 48.485  46.603  27.272  1.00 35.08  ? 114 PHE E CZ  1 
ATOM   15083 N N   . THR E 1 115 ? 44.627  45.576  20.977  1.00 41.77  ? 115 THR E N   1 
ATOM   15084 C CA  . THR E 1 115 ? 43.938  46.003  19.765  1.00 43.99  ? 115 THR E CA  1 
ATOM   15085 C C   . THR E 1 115 ? 42.554  45.364  19.695  1.00 42.78  ? 115 THR E C   1 
ATOM   15086 O O   . THR E 1 115 ? 41.554  46.062  19.553  1.00 51.63  ? 115 THR E O   1 
ATOM   15087 C CB  . THR E 1 115 ? 44.773  45.649  18.534  1.00 47.49  ? 115 THR E CB  1 
ATOM   15088 O OG1 . THR E 1 115 ? 45.697  46.729  18.506  1.00 45.29  ? 115 THR E OG1 1 
ATOM   15089 C CG2 . THR E 1 115 ? 43.958  45.569  17.252  1.00 48.06  ? 115 THR E CG2 1 
ATOM   15090 N N   . LYS E 1 116 ? 42.509  44.033  19.755  1.00 35.61  ? 116 LYS E N   1 
ATOM   15091 C CA  . LYS E 1 116 ? 41.268  43.308  19.928  1.00 36.83  ? 116 LYS E CA  1 
ATOM   15092 C C   . LYS E 1 116 ? 40.368  43.965  20.991  1.00 42.07  ? 116 LYS E C   1 
ATOM   15093 O O   . LYS E 1 116 ? 39.177  44.156  20.743  1.00 38.56  ? 116 LYS E O   1 
ATOM   15094 C CB  . LYS E 1 116 ? 41.638  41.873  20.303  1.00 41.64  ? 116 LYS E CB  1 
ATOM   15095 C CG  . LYS E 1 116 ? 40.478  41.026  20.816  1.00 55.29  ? 116 LYS E CG  1 
ATOM   15096 C CD  . LYS E 1 116 ? 40.765  39.529  20.864  1.00 65.47  ? 116 LYS E CD  1 
ATOM   15097 C CE  . LYS E 1 116 ? 39.483  38.742  20.934  1.00 78.81  ? 116 LYS E CE  1 
ATOM   15098 N NZ  . LYS E 1 116 ? 39.669  37.324  20.610  1.00 80.22  ? 116 LYS E NZ  1 
ATOM   15099 N N   . ARG E 1 117 ? 40.929  44.295  22.180  1.00 36.07  ? 117 ARG E N   1 
ATOM   15100 C CA  . ARG E 1 117 ? 40.142  44.676  23.344  1.00 31.00  ? 117 ARG E CA  1 
ATOM   15101 C C   . ARG E 1 117 ? 39.670  46.126  23.243  1.00 28.73  ? 117 ARG E C   1 
ATOM   15102 O O   . ARG E 1 117 ? 38.688  46.511  23.894  1.00 23.98  ? 117 ARG E O   1 
ATOM   15103 C CB  . ARG E 1 117 ? 40.900  44.365  24.638  1.00 31.86  ? 117 ARG E CB  1 
ATOM   15104 C CG  . ARG E 1 117 ? 41.152  42.871  24.768  1.00 31.03  ? 117 ARG E CG  1 
ATOM   15105 C CD  . ARG E 1 117 ? 41.923  42.565  26.024  1.00 32.75  ? 117 ARG E CD  1 
ATOM   15106 N NE  . ARG E 1 117 ? 42.224  41.135  26.125  1.00 33.08  ? 117 ARG E NE  1 
ATOM   15107 C CZ  . ARG E 1 117 ? 41.801  40.289  27.035  1.00 31.92  ? 117 ARG E CZ  1 
ATOM   15108 N NH1 . ARG E 1 117 ? 40.927  40.649  27.945  1.00 33.57  ? 117 ARG E NH1 1 
ATOM   15109 N NH2 . ARG E 1 117 ? 42.261  39.060  27.026  1.00 33.91  ? 117 ARG E NH2 1 
ATOM   15110 N N   . MET E 1 118 ? 40.301  46.872  22.334  1.00 28.19  ? 118 MET E N   1 
ATOM   15111 C CA  . MET E 1 118 ? 39.986  48.267  22.094  1.00 30.57  ? 118 MET E CA  1 
ATOM   15112 C C   . MET E 1 118 ? 38.612  48.390  21.427  1.00 33.04  ? 118 MET E C   1 
ATOM   15113 O O   . MET E 1 118 ? 38.003  49.456  21.438  1.00 37.47  ? 118 MET E O   1 
ATOM   15114 C CB  . MET E 1 118 ? 41.092  48.875  21.232  1.00 31.47  ? 118 MET E CB  1 
ATOM   15115 C CG  . MET E 1 118 ? 41.401  50.291  21.553  1.00 32.85  ? 118 MET E CG  1 
ATOM   15116 S SD  . MET E 1 118 ? 42.837  50.882  20.643  1.00 36.18  ? 118 MET E SD  1 
ATOM   15117 C CE  . MET E 1 118 ? 44.233  50.375  21.654  1.00 39.23  ? 118 MET E CE  1 
ATOM   15118 N N   . GLN E 1 119 ? 38.093  47.274  20.901  1.00 33.99  ? 119 GLN E N   1 
ATOM   15119 C CA  . GLN E 1 119 ? 36.773  47.229  20.288  1.00 34.44  ? 119 GLN E CA  1 
ATOM   15120 C C   . GLN E 1 119 ? 35.670  46.956  21.302  1.00 33.40  ? 119 GLN E C   1 
ATOM   15121 O O   . GLN E 1 119 ? 34.515  46.925  20.922  1.00 36.81  ? 119 GLN E O   1 
ATOM   15122 C CB  . GLN E 1 119 ? 36.682  46.094  19.265  1.00 33.78  ? 119 GLN E CB  1 
ATOM   15123 C CG  . GLN E 1 119 ? 37.576  46.294  18.044  1.00 35.85  ? 119 GLN E CG  1 
ATOM   15124 C CD  . GLN E 1 119 ? 37.260  47.579  17.312  1.00 38.47  ? 119 GLN E CD  1 
ATOM   15125 O OE1 . GLN E 1 119 ? 36.094  47.949  17.159  1.00 43.40  ? 119 GLN E OE1 1 
ATOM   15126 N NE2 . GLN E 1 119 ? 38.283  48.300  16.876  1.00 40.99  ? 119 GLN E NE2 1 
ATOM   15127 N N   . ASN E 1 120 ? 36.018  46.728  22.568  1.00 32.10  ? 120 ASN E N   1 
ATOM   15128 C CA  . ASN E 1 120 ? 35.083  46.218  23.564  1.00 31.78  ? 120 ASN E CA  1 
ATOM   15129 C C   . ASN E 1 120 ? 34.738  47.264  24.628  1.00 27.20  ? 120 ASN E C   1 
ATOM   15130 O O   . ASN E 1 120 ? 34.324  46.909  25.732  1.00 26.98  ? 120 ASN E O   1 
ATOM   15131 C CB  . ASN E 1 120 ? 35.669  44.993  24.263  1.00 32.68  ? 120 ASN E CB  1 
ATOM   15132 C CG  . ASN E 1 120 ? 36.034  43.930  23.259  1.00 34.06  ? 120 ASN E CG  1 
ATOM   15133 O OD1 . ASN E 1 120 ? 35.683  44.034  22.076  1.00 38.10  ? 120 ASN E OD1 1 
ATOM   15134 N ND2 . ASN E 1 120 ? 36.745  42.910  23.706  1.00 33.36  ? 120 ASN E ND2 1 
ATOM   15135 N N   . VAL E 1 121 ? 34.927  48.550  24.316  1.00 23.70  ? 121 VAL E N   1 
ATOM   15136 C CA  . VAL E 1 121 ? 34.436  49.581  25.211  1.00 26.16  ? 121 VAL E CA  1 
ATOM   15137 C C   . VAL E 1 121 ? 32.904  49.617  25.126  1.00 26.40  ? 121 VAL E C   1 
ATOM   15138 O O   . VAL E 1 121 ? 32.348  49.955  24.087  1.00 25.12  ? 121 VAL E O   1 
ATOM   15139 C CB  . VAL E 1 121 ? 35.024  50.975  24.943  1.00 28.28  ? 121 VAL E CB  1 
ATOM   15140 C CG1 . VAL E 1 121 ? 34.511  51.973  25.975  1.00 31.70  ? 121 VAL E CG1 1 
ATOM   15141 C CG2 . VAL E 1 121 ? 36.547  50.969  24.945  1.00 30.46  ? 121 VAL E CG2 1 
ATOM   15142 N N   . PRO E 1 122 ? 32.170  49.315  26.220  1.00 26.20  ? 122 PRO E N   1 
ATOM   15143 C CA  . PRO E 1 122 ? 30.709  49.351  26.196  1.00 26.09  ? 122 PRO E CA  1 
ATOM   15144 C C   . PRO E 1 122 ? 30.119  50.663  25.697  1.00 24.21  ? 122 PRO E C   1 
ATOM   15145 O O   . PRO E 1 122 ? 30.668  51.723  25.963  1.00 23.82  ? 122 PRO E O   1 
ATOM   15146 C CB  . PRO E 1 122 ? 30.346  49.141  27.668  1.00 26.77  ? 122 PRO E CB  1 
ATOM   15147 C CG  . PRO E 1 122 ? 31.495  48.363  28.231  1.00 27.65  ? 122 PRO E CG  1 
ATOM   15148 C CD  . PRO E 1 122 ? 32.706  48.946  27.538  1.00 26.74  ? 122 PRO E CD  1 
ATOM   15149 N N   . GLN E 1 123 ? 28.953  50.573  25.054  1.00 24.10  ? 123 GLN E N   1 
ATOM   15150 C CA  . GLN E 1 123 ? 28.231  51.751  24.597  1.00 26.78  ? 123 GLN E CA  1 
ATOM   15151 C C   . GLN E 1 123 ? 27.886  52.676  25.774  1.00 27.86  ? 123 GLN E C   1 
ATOM   15152 O O   . GLN E 1 123 ? 28.037  53.909  25.672  1.00 26.45  ? 123 GLN E O   1 
ATOM   15153 C CB  . GLN E 1 123 ? 27.059  51.243  23.756  1.00 30.81  ? 123 GLN E CB  1 
ATOM   15154 C CG  . GLN E 1 123 ? 26.264  52.322  23.032  1.00 35.65  ? 123 GLN E CG  1 
ATOM   15155 C CD  . GLN E 1 123 ? 27.163  53.220  22.222  1.00 39.14  ? 123 GLN E CD  1 
ATOM   15156 O OE1 . GLN E 1 123 ? 27.889  52.751  21.334  1.00 45.93  ? 123 GLN E OE1 1 
ATOM   15157 N NE2 . GLN E 1 123 ? 27.155  54.506  22.556  1.00 38.15  ? 123 GLN E NE2 1 
ATOM   15158 N N   . TYR E 1 124 ? 27.488  52.093  26.918  1.00 23.84  ? 124 TYR E N   1 
ATOM   15159 C CA  . TYR E 1 124 ? 27.085  52.912  28.052  1.00 23.38  ? 124 TYR E CA  1 
ATOM   15160 C C   . TYR E 1 124 ? 28.226  53.813  28.547  1.00 23.71  ? 124 TYR E C   1 
ATOM   15161 O O   . TYR E 1 124 ? 27.988  54.872  29.135  1.00 22.71  ? 124 TYR E O   1 
ATOM   15162 C CB  . TYR E 1 124 ? 26.508  52.027  29.161  1.00 25.43  ? 124 TYR E CB  1 
ATOM   15163 C CG  . TYR E 1 124 ? 27.484  51.065  29.813  1.00 26.71  ? 124 TYR E CG  1 
ATOM   15164 C CD1 . TYR E 1 124 ? 28.375  51.499  30.786  1.00 27.83  ? 124 TYR E CD1 1 
ATOM   15165 C CD2 . TYR E 1 124 ? 27.511  49.725  29.457  1.00 28.59  ? 124 TYR E CD2 1 
ATOM   15166 C CE1 . TYR E 1 124 ? 29.278  50.626  31.364  1.00 26.72  ? 124 TYR E CE1 1 
ATOM   15167 C CE2 . TYR E 1 124 ? 28.387  48.834  30.055  1.00 26.98  ? 124 TYR E CE2 1 
ATOM   15168 C CZ  . TYR E 1 124 ? 29.280  49.299  30.997  1.00 25.83  ? 124 TYR E CZ  1 
ATOM   15169 O OH  . TYR E 1 124 ? 30.168  48.448  31.562  1.00 26.62  ? 124 TYR E OH  1 
ATOM   15170 N N   . VAL E 1 125 ? 29.481  53.420  28.318  1.00 24.71  ? 125 VAL E N   1 
ATOM   15171 C CA  . VAL E 1 125 ? 30.601  54.253  28.746  1.00 23.89  ? 125 VAL E CA  1 
ATOM   15172 C C   . VAL E 1 125 ? 30.500  55.589  28.006  1.00 22.75  ? 125 VAL E C   1 
ATOM   15173 O O   . VAL E 1 125 ? 30.659  56.647  28.598  1.00 19.68  ? 125 VAL E O   1 
ATOM   15174 C CB  . VAL E 1 125 ? 31.987  53.594  28.554  1.00 24.61  ? 125 VAL E CB  1 
ATOM   15175 C CG1 . VAL E 1 125 ? 33.128  54.595  28.676  1.00 24.66  ? 125 VAL E CG1 1 
ATOM   15176 C CG2 . VAL E 1 125 ? 32.235  52.427  29.509  1.00 24.86  ? 125 VAL E CG2 1 
ATOM   15177 N N   . PHE E 1 126 ? 30.215  55.537  26.697  1.00 25.12  ? 126 PHE E N   1 
ATOM   15178 C CA  . PHE E 1 126 ? 30.072  56.755  25.903  1.00 24.71  ? 126 PHE E CA  1 
ATOM   15179 C C   . PHE E 1 126 ? 28.863  57.555  26.388  1.00 24.83  ? 126 PHE E C   1 
ATOM   15180 O O   . PHE E 1 126 ? 28.972  58.765  26.558  1.00 22.89  ? 126 PHE E O   1 
ATOM   15181 C CB  . PHE E 1 126 ? 30.000  56.396  24.417  1.00 24.45  ? 126 PHE E CB  1 
ATOM   15182 C CG  . PHE E 1 126 ? 31.276  55.684  23.993  1.00 26.20  ? 126 PHE E CG  1 
ATOM   15183 C CD1 . PHE E 1 126 ? 32.466  56.383  23.881  1.00 27.26  ? 126 PHE E CD1 1 
ATOM   15184 C CD2 . PHE E 1 126 ? 31.301  54.316  23.806  1.00 25.39  ? 126 PHE E CD2 1 
ATOM   15185 C CE1 . PHE E 1 126 ? 33.634  55.734  23.557  1.00 26.11  ? 126 PHE E CE1 1 
ATOM   15186 C CE2 . PHE E 1 126 ? 32.464  53.683  23.459  1.00 25.46  ? 126 PHE E CE2 1 
ATOM   15187 C CZ  . PHE E 1 126 ? 33.630  54.392  23.354  1.00 26.54  ? 126 PHE E CZ  1 
ATOM   15188 N N   . ASP E 1 127 ? 27.734  56.863  26.638  1.00 24.36  ? 127 ASP E N   1 
ATOM   15189 C CA  . ASP E 1 127 ? 26.547  57.489  27.199  1.00 25.18  ? 127 ASP E CA  1 
ATOM   15190 C C   . ASP E 1 127 ? 26.883  58.299  28.446  1.00 26.75  ? 127 ASP E C   1 
ATOM   15191 O O   . ASP E 1 127 ? 26.435  59.434  28.565  1.00 25.19  ? 127 ASP E O   1 
ATOM   15192 C CB  . ASP E 1 127 ? 25.479  56.457  27.491  1.00 26.01  ? 127 ASP E CB  1 
ATOM   15193 C CG  . ASP E 1 127 ? 24.902  55.804  26.246  1.00 28.95  ? 127 ASP E CG  1 
ATOM   15194 O OD1 . ASP E 1 127 ? 25.122  56.378  25.145  1.00 29.66  ? 127 ASP E OD1 1 
ATOM   15195 O OD2 . ASP E 1 127 ? 24.290  54.713  26.383  1.00 29.13  ? 127 ASP E OD2 1 
ATOM   15196 N N   . VAL E 1 128 ? 27.685  57.712  29.355  1.00 26.36  ? 128 VAL E N   1 
ATOM   15197 C CA  . VAL E 1 128 ? 28.051  58.390  30.586  1.00 27.15  ? 128 VAL E CA  1 
ATOM   15198 C C   . VAL E 1 128 ? 28.880  59.626  30.227  1.00 29.04  ? 128 VAL E C   1 
ATOM   15199 O O   . VAL E 1 128 ? 28.579  60.742  30.655  1.00 34.56  ? 128 VAL E O   1 
ATOM   15200 C CB  . VAL E 1 128 ? 28.745  57.436  31.592  1.00 25.32  ? 128 VAL E CB  1 
ATOM   15201 C CG1 . VAL E 1 128 ? 29.400  58.153  32.770  1.00 25.48  ? 128 VAL E CG1 1 
ATOM   15202 C CG2 . VAL E 1 128 ? 27.774  56.395  32.137  1.00 22.54  ? 128 VAL E CG2 1 
ATOM   15203 N N   . LEU E 1 129 ? 29.919  59.435  29.421  1.00 29.07  ? 129 LEU E N   1 
ATOM   15204 C CA  . LEU E 1 129 ? 30.779  60.544  29.042  1.00 30.38  ? 129 LEU E CA  1 
ATOM   15205 C C   . LEU E 1 129 ? 29.953  61.701  28.460  1.00 28.32  ? 129 LEU E C   1 
ATOM   15206 O O   . LEU E 1 129 ? 30.162  62.859  28.832  1.00 27.11  ? 129 LEU E O   1 
ATOM   15207 C CB  . LEU E 1 129 ? 31.868  60.025  28.090  1.00 28.47  ? 129 LEU E CB  1 
ATOM   15208 C CG  . LEU E 1 129 ? 32.952  59.147  28.726  1.00 25.00  ? 129 LEU E CG  1 
ATOM   15209 C CD1 . LEU E 1 129 ? 33.805  58.446  27.709  1.00 24.37  ? 129 LEU E CD1 1 
ATOM   15210 C CD2 . LEU E 1 129 ? 33.864  59.952  29.623  1.00 25.17  ? 129 LEU E CD2 1 
ATOM   15211 N N   . ARG E 1 130 ? 29.017  61.377  27.558  1.00 29.10  ? 130 ARG E N   1 
ATOM   15212 C CA  . ARG E 1 130 ? 28.159  62.371  26.921  1.00 30.47  ? 130 ARG E CA  1 
ATOM   15213 C C   . ARG E 1 130 ? 27.188  63.033  27.900  1.00 26.35  ? 130 ARG E C   1 
ATOM   15214 O O   . ARG E 1 130 ? 26.801  64.184  27.691  1.00 23.07  ? 130 ARG E O   1 
ATOM   15215 C CB  . ARG E 1 130 ? 27.260  61.825  25.809  1.00 30.71  ? 130 ARG E CB  1 
ATOM   15216 C CG  . ARG E 1 130 ? 27.990  61.709  24.488  1.00 31.88  ? 130 ARG E CG  1 
ATOM   15217 C CD  . ARG E 1 130 ? 27.074  61.571  23.285  1.00 29.55  ? 130 ARG E CD  1 
ATOM   15218 N NE  . ARG E 1 130 ? 26.802  62.831  22.596  1.00 26.88  ? 130 ARG E NE  1 
ATOM   15219 C CZ  . ARG E 1 130 ? 27.659  63.546  21.876  1.00 26.73  ? 130 ARG E CZ  1 
ATOM   15220 N NH1 . ARG E 1 130 ? 27.231  64.588  21.176  1.00 26.31  ? 130 ARG E NH1 1 
ATOM   15221 N NH2 . ARG E 1 130 ? 28.941  63.208  21.830  1.00 27.98  ? 130 ARG E NH2 1 
ATOM   15222 N N   . ALA E 1 131 ? 26.773  62.314  28.948  1.00 24.45  ? 131 ALA E N   1 
ATOM   15223 C CA  . ALA E 1 131 ? 25.860  62.902  29.923  1.00 23.15  ? 131 ALA E CA  1 
ATOM   15224 C C   . ALA E 1 131 ? 26.543  63.987  30.740  1.00 22.13  ? 131 ALA E C   1 
ATOM   15225 O O   . ALA E 1 131 ? 25.847  64.882  31.194  1.00 22.98  ? 131 ALA E O   1 
ATOM   15226 C CB  . ALA E 1 131 ? 25.268  61.852  30.818  1.00 24.58  ? 131 ALA E CB  1 
ATOM   15227 N N   . MET E 1 132 ? 27.881  63.908  30.902  1.00 22.52  ? 132 MET E N   1 
ATOM   15228 C CA  . MET E 1 132 ? 28.670  64.952  31.551  1.00 21.96  ? 132 MET E CA  1 
ATOM   15229 C C   . MET E 1 132 ? 28.727  66.216  30.686  1.00 22.36  ? 132 MET E C   1 
ATOM   15230 O O   . MET E 1 132 ? 29.046  66.165  29.507  1.00 25.16  ? 132 MET E O   1 
ATOM   15231 C CB  . MET E 1 132 ? 30.095  64.460  31.843  1.00 21.86  ? 132 MET E CB  1 
ATOM   15232 C CG  . MET E 1 132 ? 30.137  63.115  32.598  1.00 22.26  ? 132 MET E CG  1 
ATOM   15233 S SD  . MET E 1 132 ? 31.774  62.403  32.895  1.00 20.18  ? 132 MET E SD  1 
ATOM   15234 C CE  . MET E 1 132 ? 32.106  63.335  34.396  1.00 20.64  ? 132 MET E CE  1 
ATOM   15235 N N   . PRO E 1 133 ? 28.444  67.417  31.222  1.00 20.73  ? 133 PRO E N   1 
ATOM   15236 C CA  . PRO E 1 133 ? 28.582  68.632  30.438  1.00 22.67  ? 133 PRO E CA  1 
ATOM   15237 C C   . PRO E 1 133 ? 29.980  68.686  29.827  1.00 26.82  ? 133 PRO E C   1 
ATOM   15238 O O   . PRO E 1 133 ? 30.953  68.244  30.430  1.00 31.18  ? 133 PRO E O   1 
ATOM   15239 C CB  . PRO E 1 133 ? 28.372  69.756  31.462  1.00 23.39  ? 133 PRO E CB  1 
ATOM   15240 C CG  . PRO E 1 133 ? 27.632  69.121  32.599  1.00 22.56  ? 133 PRO E CG  1 
ATOM   15241 C CD  . PRO E 1 133 ? 28.028  67.668  32.598  1.00 21.42  ? 133 PRO E CD  1 
ATOM   15242 N N   . VAL E 1 134 ? 30.080  69.297  28.650  1.00 28.01  ? 134 VAL E N   1 
ATOM   15243 C CA  . VAL E 1 134 ? 31.297  69.270  27.863  1.00 26.15  ? 134 VAL E CA  1 
ATOM   15244 C C   . VAL E 1 134 ? 32.414  70.101  28.510  1.00 23.45  ? 134 VAL E C   1 
ATOM   15245 O O   . VAL E 1 134 ? 33.574  69.853  28.213  1.00 23.48  ? 134 VAL E O   1 
ATOM   15246 C CB  . VAL E 1 134 ? 31.032  69.707  26.403  1.00 25.77  ? 134 VAL E CB  1 
ATOM   15247 C CG1 . VAL E 1 134 ? 30.894  71.231  26.234  1.00 24.22  ? 134 VAL E CG1 1 
ATOM   15248 C CG2 . VAL E 1 134 ? 32.123  69.164  25.483  1.00 26.40  ? 134 VAL E CG2 1 
ATOM   15249 N N   . ASP E 1 135 ? 32.085  71.036  29.403  1.00 22.87  ? 135 ASP E N   1 
ATOM   15250 C CA  . ASP E 1 135 ? 33.085  71.871  30.074  1.00 24.45  ? 135 ASP E CA  1 
ATOM   15251 C C   . ASP E 1 135 ? 33.555  71.264  31.406  1.00 24.28  ? 135 ASP E C   1 
ATOM   15252 O O   . ASP E 1 135 ? 34.223  71.928  32.200  1.00 24.97  ? 135 ASP E O   1 
ATOM   15253 C CB  . ASP E 1 135 ? 32.513  73.247  30.367  1.00 22.27  ? 135 ASP E CB  1 
ATOM   15254 C CG  . ASP E 1 135 ? 31.253  73.217  31.216  1.00 24.31  ? 135 ASP E CG  1 
ATOM   15255 O OD1 . ASP E 1 135 ? 30.767  72.095  31.554  1.00 22.08  ? 135 ASP E OD1 1 
ATOM   15256 O OD2 . ASP E 1 135 ? 30.780  74.305  31.569  1.00 28.06  ? 135 ASP E OD2 1 
ATOM   15257 N N   . THR E 1 136 ? 33.151  70.021  31.693  1.00 23.64  ? 136 THR E N   1 
ATOM   15258 C CA  . THR E 1 136 ? 33.685  69.280  32.829  1.00 23.57  ? 136 THR E CA  1 
ATOM   15259 C C   . THR E 1 136 ? 35.176  69.041  32.619  1.00 25.52  ? 136 THR E C   1 
ATOM   15260 O O   . THR E 1 136 ? 35.577  68.737  31.495  1.00 31.24  ? 136 THR E O   1 
ATOM   15261 C CB  . THR E 1 136 ? 32.965  67.940  32.956  1.00 21.73  ? 136 THR E CB  1 
ATOM   15262 O OG1 . THR E 1 136 ? 31.581  68.152  33.256  1.00 18.86  ? 136 THR E OG1 1 
ATOM   15263 C CG2 . THR E 1 136 ? 33.607  67.079  34.024  1.00 22.05  ? 136 THR E CG2 1 
ATOM   15264 N N   . HIS E 1 137 ? 35.985  69.163  33.691  1.00 23.42  ? 137 HIS E N   1 
ATOM   15265 C CA  . HIS E 1 137 ? 37.421  68.936  33.603  1.00 20.85  ? 137 HIS E CA  1 
ATOM   15266 C C   . HIS E 1 137 ? 37.665  67.570  32.962  1.00 22.39  ? 137 HIS E C   1 
ATOM   15267 O O   . HIS E 1 137 ? 36.948  66.627  33.277  1.00 22.94  ? 137 HIS E O   1 
ATOM   15268 C CB  . HIS E 1 137 ? 38.104  69.046  34.971  1.00 20.58  ? 137 HIS E CB  1 
ATOM   15269 C CG  . HIS E 1 137 ? 39.599  69.144  34.901  1.00 19.53  ? 137 HIS E CG  1 
ATOM   15270 N ND1 . HIS E 1 137 ? 40.389  68.064  34.563  1.00 19.08  ? 137 HIS E ND1 1 
ATOM   15271 C CD2 . HIS E 1 137 ? 40.424  70.217  34.994  1.00 17.75  ? 137 HIS E CD2 1 
ATOM   15272 C CE1 . HIS E 1 137 ? 41.653  68.470  34.510  1.00 19.20  ? 137 HIS E CE1 1 
ATOM   15273 N NE2 . HIS E 1 137 ? 41.684  69.785  34.749  1.00 18.35  ? 137 HIS E NE2 1 
ATOM   15274 N N   . PRO E 1 138 ? 38.626  67.422  32.008  1.00 24.28  ? 138 PRO E N   1 
ATOM   15275 C CA  . PRO E 1 138 ? 38.853  66.126  31.336  1.00 24.47  ? 138 PRO E CA  1 
ATOM   15276 C C   . PRO E 1 138 ? 39.333  64.975  32.238  1.00 24.76  ? 138 PRO E C   1 
ATOM   15277 O O   . PRO E 1 138 ? 39.143  63.805  31.909  1.00 24.54  ? 138 PRO E O   1 
ATOM   15278 C CB  . PRO E 1 138 ? 39.884  66.488  30.238  1.00 22.99  ? 138 PRO E CB  1 
ATOM   15279 C CG  . PRO E 1 138 ? 40.587  67.748  30.772  1.00 22.30  ? 138 PRO E CG  1 
ATOM   15280 C CD  . PRO E 1 138 ? 39.493  68.498  31.490  1.00 22.05  ? 138 PRO E CD  1 
ATOM   15281 N N   . MET E 1 139 ? 39.914  65.299  33.404  1.00 22.79  ? 139 MET E N   1 
ATOM   15282 C CA  . MET E 1 139 ? 40.369  64.275  34.335  1.00 23.19  ? 139 MET E CA  1 
ATOM   15283 C C   . MET E 1 139 ? 39.191  63.737  35.161  1.00 23.52  ? 139 MET E C   1 
ATOM   15284 O O   . MET E 1 139 ? 39.178  62.569  35.573  1.00 24.26  ? 139 MET E O   1 
ATOM   15285 C CB  . MET E 1 139 ? 41.495  64.836  35.220  1.00 24.68  ? 139 MET E CB  1 
ATOM   15286 C CG  . MET E 1 139 ? 42.882  64.817  34.598  1.00 23.64  ? 139 MET E CG  1 
ATOM   15287 S SD  . MET E 1 139 ? 43.409  63.132  34.228  1.00 23.49  ? 139 MET E SD  1 
ATOM   15288 C CE  . MET E 1 139 ? 43.803  62.464  35.850  1.00 29.90  ? 139 MET E CE  1 
ATOM   15289 N N   . THR E 1 140 ? 38.166  64.580  35.379  1.00 23.81  ? 140 THR E N   1 
ATOM   15290 C CA  . THR E 1 140 ? 36.892  64.121  35.918  1.00 22.28  ? 140 THR E CA  1 
ATOM   15291 C C   . THR E 1 140 ? 36.207  63.204  34.910  1.00 22.04  ? 140 THR E C   1 
ATOM   15292 O O   . THR E 1 140 ? 35.776  62.103  35.272  1.00 20.86  ? 140 THR E O   1 
ATOM   15293 C CB  . THR E 1 140 ? 36.042  65.332  36.284  1.00 23.78  ? 140 THR E CB  1 
ATOM   15294 O OG1 . THR E 1 140 ? 36.793  66.141  37.188  1.00 24.71  ? 140 THR E OG1 1 
ATOM   15295 C CG2 . THR E 1 140 ? 34.761  64.960  37.004  1.00 23.12  ? 140 THR E CG2 1 
ATOM   15296 N N   . MET E 1 141 ? 36.113  63.643  33.636  1.00 21.37  ? 141 MET E N   1 
ATOM   15297 C CA  . MET E 1 141 ? 35.534  62.780  32.611  1.00 20.24  ? 141 MET E CA  1 
ATOM   15298 C C   . MET E 1 141 ? 36.309  61.453  32.539  1.00 20.48  ? 141 MET E C   1 
ATOM   15299 O O   . MET E 1 141 ? 35.716  60.378  32.451  1.00 19.94  ? 141 MET E O   1 
ATOM   15300 C CB  . MET E 1 141 ? 35.565  63.410  31.215  1.00 20.06  ? 141 MET E CB  1 
ATOM   15301 C CG  . MET E 1 141 ? 34.780  64.668  31.045  1.00 20.77  ? 141 MET E CG  1 
ATOM   15302 S SD  . MET E 1 141 ? 34.762  65.189  29.315  1.00 26.32  ? 141 MET E SD  1 
ATOM   15303 C CE  . MET E 1 141 ? 33.713  66.657  29.266  1.00 25.43  ? 141 MET E CE  1 
ATOM   15304 N N   . PHE E 1 142 ? 37.650  61.526  32.531  1.00 20.18  ? 142 PHE E N   1 
ATOM   15305 C CA  . PHE E 1 142 ? 38.488  60.348  32.357  1.00 20.57  ? 142 PHE E CA  1 
ATOM   15306 C C   . PHE E 1 142 ? 38.203  59.353  33.479  1.00 22.98  ? 142 PHE E C   1 
ATOM   15307 O O   . PHE E 1 142 ? 37.919  58.187  33.228  1.00 24.46  ? 142 PHE E O   1 
ATOM   15308 C CB  . PHE E 1 142 ? 39.962  60.757  32.384  1.00 20.23  ? 142 PHE E CB  1 
ATOM   15309 C CG  . PHE E 1 142 ? 40.945  59.673  31.984  1.00 21.06  ? 142 PHE E CG  1 
ATOM   15310 C CD1 . PHE E 1 142 ? 40.785  58.963  30.800  1.00 22.68  ? 142 PHE E CD1 1 
ATOM   15311 C CD2 . PHE E 1 142 ? 42.043  59.375  32.785  1.00 23.11  ? 142 PHE E CD2 1 
ATOM   15312 C CE1 . PHE E 1 142 ? 41.704  57.992  30.417  1.00 22.14  ? 142 PHE E CE1 1 
ATOM   15313 C CE2 . PHE E 1 142 ? 42.955  58.403  32.400  1.00 22.94  ? 142 PHE E CE2 1 
ATOM   15314 C CZ  . PHE E 1 142 ? 42.786  57.723  31.213  1.00 22.31  ? 142 PHE E CZ  1 
ATOM   15315 N N   . ALA E 1 143 ? 38.241  59.836  34.732  1.00 24.00  ? 143 ALA E N   1 
ATOM   15316 C CA  . ALA E 1 143 ? 38.034  58.970  35.877  1.00 23.34  ? 143 ALA E CA  1 
ATOM   15317 C C   . ALA E 1 143 ? 36.593  58.447  35.879  1.00 22.44  ? 143 ALA E C   1 
ATOM   15318 O O   . ALA E 1 143 ? 36.389  57.255  36.105  1.00 23.52  ? 143 ALA E O   1 
ATOM   15319 C CB  . ALA E 1 143 ? 38.445  59.703  37.152  1.00 25.42  ? 143 ALA E CB  1 
ATOM   15320 N N   . ALA E 1 144 ? 35.599  59.283  35.536  1.00 20.56  ? 144 ALA E N   1 
ATOM   15321 C CA  . ALA E 1 144 ? 34.215  58.809  35.533  1.00 22.58  ? 144 ALA E CA  1 
ATOM   15322 C C   . ALA E 1 144 ? 33.946  57.732  34.489  1.00 23.99  ? 144 ALA E C   1 
ATOM   15323 O O   . ALA E 1 144 ? 33.144  56.844  34.744  1.00 24.39  ? 144 ALA E O   1 
ATOM   15324 C CB  . ALA E 1 144 ? 33.234  59.944  35.335  1.00 24.00  ? 144 ALA E CB  1 
ATOM   15325 N N   . GLY E 1 145 ? 34.536  57.857  33.291  1.00 24.79  ? 145 GLY E N   1 
ATOM   15326 C CA  . GLY E 1 145 ? 34.349  56.852  32.260  1.00 24.75  ? 145 GLY E CA  1 
ATOM   15327 C C   . GLY E 1 145 ? 34.982  55.519  32.667  1.00 26.54  ? 145 GLY E C   1 
ATOM   15328 O O   . GLY E 1 145 ? 34.412  54.446  32.450  1.00 27.89  ? 145 GLY E O   1 
ATOM   15329 N N   . ILE E 1 146 ? 36.183  55.588  33.249  1.00 26.32  ? 146 ILE E N   1 
ATOM   15330 C CA  . ILE E 1 146 ? 36.855  54.384  33.713  1.00 27.07  ? 146 ILE E CA  1 
ATOM   15331 C C   . ILE E 1 146 ? 35.987  53.707  34.775  1.00 25.60  ? 146 ILE E C   1 
ATOM   15332 O O   . ILE E 1 146 ? 35.762  52.495  34.726  1.00 22.47  ? 146 ILE E O   1 
ATOM   15333 C CB  . ILE E 1 146 ? 38.254  54.707  34.260  1.00 28.31  ? 146 ILE E CB  1 
ATOM   15334 C CG1 . ILE E 1 146 ? 39.165  55.286  33.176  1.00 29.48  ? 146 ILE E CG1 1 
ATOM   15335 C CG2 . ILE E 1 146 ? 38.861  53.472  34.911  1.00 28.31  ? 146 ILE E CG2 1 
ATOM   15336 C CD1 . ILE E 1 146 ? 40.322  56.123  33.700  1.00 29.31  ? 146 ILE E CD1 1 
ATOM   15337 N N   . LEU E 1 147 ? 35.494  54.512  35.722  1.00 23.42  ? 147 LEU E N   1 
ATOM   15338 C CA  . LEU E 1 147 ? 34.680  53.997  36.816  1.00 24.31  ? 147 LEU E CA  1 
ATOM   15339 C C   . LEU E 1 147 ? 33.405  53.332  36.297  1.00 23.58  ? 147 LEU E C   1 
ATOM   15340 O O   . LEU E 1 147 ? 33.014  52.282  36.789  1.00 21.69  ? 147 LEU E O   1 
ATOM   15341 C CB  . LEU E 1 147 ? 34.349  55.127  37.789  1.00 24.02  ? 147 LEU E CB  1 
ATOM   15342 C CG  . LEU E 1 147 ? 33.401  54.800  38.933  1.00 23.15  ? 147 LEU E CG  1 
ATOM   15343 C CD1 . LEU E 1 147 ? 33.903  53.607  39.677  1.00 24.29  ? 147 LEU E CD1 1 
ATOM   15344 C CD2 . LEU E 1 147 ? 33.278  55.989  39.844  1.00 23.46  ? 147 LEU E CD2 1 
ATOM   15345 N N   . ALA E 1 148 ? 32.758  53.943  35.307  1.00 22.55  ? 148 ALA E N   1 
ATOM   15346 C CA  . ALA E 1 148 ? 31.549  53.370  34.745  1.00 23.74  ? 148 ALA E CA  1 
ATOM   15347 C C   . ALA E 1 148 ? 31.833  51.972  34.195  1.00 26.26  ? 148 ALA E C   1 
ATOM   15348 O O   . ALA E 1 148 ? 30.942  51.116  34.183  1.00 24.69  ? 148 ALA E O   1 
ATOM   15349 C CB  . ALA E 1 148 ? 31.002  54.269  33.664  1.00 23.59  ? 148 ALA E CB  1 
ATOM   15350 N N   . MET E 1 149 ? 33.078  51.738  33.737  1.00 26.64  ? 149 MET E N   1 
ATOM   15351 C CA  . MET E 1 149 ? 33.401  50.474  33.105  1.00 24.09  ? 149 MET E CA  1 
ATOM   15352 C C   . MET E 1 149 ? 33.571  49.380  34.152  1.00 22.57  ? 149 MET E C   1 
ATOM   15353 O O   . MET E 1 149 ? 33.701  48.230  33.804  1.00 21.62  ? 149 MET E O   1 
ATOM   15354 C CB  . MET E 1 149 ? 34.638  50.603  32.223  1.00 26.35  ? 149 MET E CB  1 
ATOM   15355 C CG  . MET E 1 149 ? 34.857  49.384  31.332  1.00 28.21  ? 149 MET E CG  1 
ATOM   15356 S SD  . MET E 1 149 ? 35.882  49.745  29.898  1.00 26.07  ? 149 MET E SD  1 
ATOM   15357 C CE  . MET E 1 149 ? 36.197  48.042  29.426  1.00 27.01  ? 149 MET E CE  1 
ATOM   15358 N N   . GLN E 1 150 ? 33.465  49.728  35.437  1.00 26.48  ? 150 GLN E N   1 
ATOM   15359 C CA  . GLN E 1 150 ? 33.579  48.782  36.537  1.00 27.95  ? 150 GLN E CA  1 
ATOM   15360 C C   . GLN E 1 150 ? 32.589  47.631  36.419  1.00 27.38  ? 150 GLN E C   1 
ATOM   15361 O O   . GLN E 1 150 ? 32.823  46.610  37.035  1.00 29.87  ? 150 GLN E O   1 
ATOM   15362 C CB  . GLN E 1 150 ? 33.382  49.466  37.889  1.00 28.47  ? 150 GLN E CB  1 
ATOM   15363 C CG  . GLN E 1 150 ? 33.605  48.586  39.116  1.00 29.97  ? 150 GLN E CG  1 
ATOM   15364 C CD  . GLN E 1 150 ? 32.422  47.712  39.489  1.00 31.12  ? 150 GLN E CD  1 
ATOM   15365 O OE1 . GLN E 1 150 ? 31.254  48.081  39.299  1.00 28.51  ? 150 GLN E OE1 1 
ATOM   15366 N NE2 . GLN E 1 150 ? 32.725  46.521  39.999  1.00 30.04  ? 150 GLN E NE2 1 
ATOM   15367 N N   . ARG E 1 151 ? 31.523  47.777  35.628  1.00 27.84  ? 151 ARG E N   1 
ATOM   15368 C CA  . ARG E 1 151 ? 30.481  46.763  35.543  1.00 27.87  ? 151 ARG E CA  1 
ATOM   15369 C C   . ARG E 1 151 ? 31.020  45.549  34.807  1.00 26.94  ? 151 ARG E C   1 
ATOM   15370 O O   . ARG E 1 151 ? 30.544  44.445  35.012  1.00 26.61  ? 151 ARG E O   1 
ATOM   15371 C CB  . ARG E 1 151 ? 29.221  47.282  34.832  1.00 29.01  ? 151 ARG E CB  1 
ATOM   15372 C CG  . ARG E 1 151 ? 28.121  46.272  34.526  1.00 33.35  ? 151 ARG E CG  1 
ATOM   15373 C CD  . ARG E 1 151 ? 27.077  46.919  33.620  1.00 39.28  ? 151 ARG E CD  1 
ATOM   15374 N NE  . ARG E 1 151 ? 25.965  46.063  33.186  1.00 45.61  ? 151 ARG E NE  1 
ATOM   15375 C CZ  . ARG E 1 151 ? 25.813  45.455  31.996  1.00 45.06  ? 151 ARG E CZ  1 
ATOM   15376 N NH1 . ARG E 1 151 ? 26.861  45.250  31.200  1.00 40.83  ? 151 ARG E NH1 1 
ATOM   15377 N NH2 . ARG E 1 151 ? 24.613  44.986  31.652  1.00 43.93  ? 151 ARG E NH2 1 
ATOM   15378 N N   . GLU E 1 152 ? 32.044  45.743  33.976  1.00 29.11  ? 152 GLU E N   1 
ATOM   15379 C CA  . GLU E 1 152 ? 32.607  44.635  33.211  1.00 29.17  ? 152 GLU E CA  1 
ATOM   15380 C C   . GLU E 1 152 ? 33.754  43.928  33.958  1.00 26.45  ? 152 GLU E C   1 
ATOM   15381 O O   . GLU E 1 152 ? 34.389  43.030  33.408  1.00 27.36  ? 152 GLU E O   1 
ATOM   15382 C CB  . GLU E 1 152 ? 33.016  45.159  31.832  1.00 26.69  ? 152 GLU E CB  1 
ATOM   15383 C CG  . GLU E 1 152 ? 31.959  46.013  31.137  1.00 26.18  ? 152 GLU E CG  1 
ATOM   15384 C CD  . GLU E 1 152 ? 30.594  45.368  31.036  1.00 25.62  ? 152 GLU E CD  1 
ATOM   15385 O OE1 . GLU E 1 152 ? 29.556  46.065  31.203  1.00 24.89  ? 152 GLU E OE1 1 
ATOM   15386 O OE2 . GLU E 1 152 ? 30.594  44.144  30.834  1.00 22.28  ? 152 GLU E OE2 1 
ATOM   15387 N N   . SER E 1 153 ? 33.973  44.278  35.229  1.00 27.03  ? 153 SER E N   1 
ATOM   15388 C CA  . SER E 1 153 ? 35.132  43.817  35.984  1.00 28.22  ? 153 SER E CA  1 
ATOM   15389 C C   . SER E 1 153 ? 35.040  42.319  36.184  1.00 28.84  ? 153 SER E C   1 
ATOM   15390 O O   . SER E 1 153 ? 34.046  41.830  36.706  1.00 31.79  ? 153 SER E O   1 
ATOM   15391 C CB  . SER E 1 153 ? 35.247  44.517  37.339  1.00 31.57  ? 153 SER E CB  1 
ATOM   15392 O OG  . SER E 1 153 ? 36.248  43.954  38.184  1.00 31.11  ? 153 SER E OG  1 
ATOM   15393 N N   . VAL E 1 154 ? 36.113  41.621  35.822  1.00 33.42  ? 154 VAL E N   1 
ATOM   15394 C CA  . VAL E 1 154 ? 36.202  40.177  35.976  1.00 33.43  ? 154 VAL E CA  1 
ATOM   15395 C C   . VAL E 1 154 ? 36.548  39.858  37.422  1.00 31.10  ? 154 VAL E C   1 
ATOM   15396 O O   . VAL E 1 154 ? 36.019  38.909  37.991  1.00 27.74  ? 154 VAL E O   1 
ATOM   15397 C CB  . VAL E 1 154 ? 37.227  39.588  34.984  1.00 32.13  ? 154 VAL E CB  1 
ATOM   15398 C CG1 . VAL E 1 154 ? 37.646  38.189  35.380  1.00 32.77  ? 154 VAL E CG1 1 
ATOM   15399 C CG2 . VAL E 1 154 ? 36.672  39.584  33.556  1.00 32.73  ? 154 VAL E CG2 1 
ATOM   15400 N N   . PHE E 1 155 ? 37.454  40.656  37.993  1.00 30.33  ? 155 PHE E N   1 
ATOM   15401 C CA  . PHE E 1 155 ? 37.759  40.532  39.403  1.00 30.34  ? 155 PHE E CA  1 
ATOM   15402 C C   . PHE E 1 155 ? 36.479  40.615  40.223  1.00 29.57  ? 155 PHE E C   1 
ATOM   15403 O O   . PHE E 1 155 ? 36.177  39.702  40.966  1.00 29.49  ? 155 PHE E O   1 
ATOM   15404 C CB  . PHE E 1 155 ? 38.719  41.615  39.881  1.00 30.84  ? 155 PHE E CB  1 
ATOM   15405 C CG  . PHE E 1 155 ? 39.263  41.332  41.274  1.00 30.78  ? 155 PHE E CG  1 
ATOM   15406 C CD1 . PHE E 1 155 ? 38.578  41.759  42.409  1.00 30.38  ? 155 PHE E CD1 1 
ATOM   15407 C CD2 . PHE E 1 155 ? 40.450  40.629  41.445  1.00 29.30  ? 155 PHE E CD2 1 
ATOM   15408 C CE1 . PHE E 1 155 ? 39.082  41.512  43.672  1.00 31.13  ? 155 PHE E CE1 1 
ATOM   15409 C CE2 . PHE E 1 155 ? 40.940  40.371  42.717  1.00 30.50  ? 155 PHE E CE2 1 
ATOM   15410 C CZ  . PHE E 1 155 ? 40.260  40.812  43.824  1.00 30.26  ? 155 PHE E CZ  1 
ATOM   15411 N N   . ALA E 1 156 ? 35.729  41.710  40.085  1.00 33.69  ? 156 ALA E N   1 
ATOM   15412 C CA  . ALA E 1 156 ? 34.534  41.915  40.883  1.00 36.36  ? 156 ALA E CA  1 
ATOM   15413 C C   . ALA E 1 156 ? 33.653  40.677  40.835  1.00 38.61  ? 156 ALA E C   1 
ATOM   15414 O O   . ALA E 1 156 ? 33.290  40.143  41.883  1.00 41.23  ? 156 ALA E O   1 
ATOM   15415 C CB  . ALA E 1 156 ? 33.770  43.114  40.401  1.00 36.30  ? 156 ALA E CB  1 
ATOM   15416 N N   . LYS E 1 157 ? 33.323  40.246  39.614  1.00 37.64  ? 157 LYS E N   1 
ATOM   15417 C CA  . LYS E 1 157 ? 32.397  39.148  39.403  1.00 40.43  ? 157 LYS E CA  1 
ATOM   15418 C C   . LYS E 1 157 ? 32.909  37.825  39.975  1.00 39.10  ? 157 LYS E C   1 
ATOM   15419 O O   . LYS E 1 157 ? 32.135  37.085  40.576  1.00 32.75  ? 157 LYS E O   1 
ATOM   15420 C CB  . LYS E 1 157 ? 32.155  38.939  37.909  1.00 45.18  ? 157 LYS E CB  1 
ATOM   15421 C CG  . LYS E 1 157 ? 31.227  37.779  37.610  1.00 52.66  ? 157 LYS E CG  1 
ATOM   15422 C CD  . LYS E 1 157 ? 31.155  37.346  36.157  1.00 62.34  ? 157 LYS E CD  1 
ATOM   15423 C CE  . LYS E 1 157 ? 29.912  36.535  35.992  1.00 76.05  ? 157 LYS E CE  1 
ATOM   15424 N NZ  . LYS E 1 157 ? 30.023  35.619  34.855  1.00 78.74  ? 157 LYS E NZ  1 
ATOM   15425 N N   . ARG E 1 158 ? 34.183  37.500  39.719  1.00 41.81  ? 158 ARG E N   1 
ATOM   15426 C CA  . ARG E 1 158 ? 34.796  36.273  40.216  1.00 44.51  ? 158 ARG E CA  1 
ATOM   15427 C C   . ARG E 1 158 ? 34.921  36.287  41.747  1.00 41.60  ? 158 ARG E C   1 
ATOM   15428 O O   . ARG E 1 158 ? 34.798  35.239  42.381  1.00 38.45  ? 158 ARG E O   1 
ATOM   15429 C CB  . ARG E 1 158 ? 36.123  35.961  39.506  1.00 48.88  ? 158 ARG E CB  1 
ATOM   15430 C CG  . ARG E 1 158 ? 35.983  34.968  38.355  1.00 57.88  ? 158 ARG E CG  1 
ATOM   15431 C CD  . ARG E 1 158 ? 37.244  34.133  38.107  1.00 73.36  ? 158 ARG E CD  1 
ATOM   15432 N NE  . ARG E 1 158 ? 38.187  34.735  37.149  1.00 92.43  ? 158 ARG E NE  1 
ATOM   15433 C CZ  . ARG E 1 158 ? 39.514  34.507  37.069  1.00 96.27  ? 158 ARG E CZ  1 
ATOM   15434 N NH1 . ARG E 1 158 ? 40.210  35.039  36.072  1.00 85.17  ? 158 ARG E NH1 1 
ATOM   15435 N NH2 . ARG E 1 158 ? 40.140  33.754  37.971  1.00 90.33  ? 158 ARG E NH2 1 
ATOM   15436 N N   . TYR E 1 159 ? 35.114  37.463  42.358  1.00 39.84  ? 159 TYR E N   1 
ATOM   15437 C CA  . TYR E 1 159 ? 35.184  37.551  43.809  1.00 44.24  ? 159 TYR E CA  1 
ATOM   15438 C C   . TYR E 1 159 ? 33.844  37.154  44.439  1.00 45.85  ? 159 TYR E C   1 
ATOM   15439 O O   . TYR E 1 159 ? 33.812  36.607  45.542  1.00 50.25  ? 159 TYR E O   1 
ATOM   15440 C CB  . TYR E 1 159 ? 35.575  38.933  44.352  1.00 43.84  ? 159 TYR E CB  1 
ATOM   15441 C CG  . TYR E 1 159 ? 35.844  38.882  45.849  1.00 43.12  ? 159 TYR E CG  1 
ATOM   15442 C CD1 . TYR E 1 159 ? 34.805  38.975  46.768  1.00 44.85  ? 159 TYR E CD1 1 
ATOM   15443 C CD2 . TYR E 1 159 ? 37.126  38.649  46.342  1.00 47.16  ? 159 TYR E CD2 1 
ATOM   15444 C CE1 . TYR E 1 159 ? 35.035  38.860  48.131  1.00 47.74  ? 159 TYR E CE1 1 
ATOM   15445 C CE2 . TYR E 1 159 ? 37.375  38.539  47.703  1.00 47.95  ? 159 TYR E CE2 1 
ATOM   15446 C CZ  . TYR E 1 159 ? 36.323  38.648  48.598  1.00 47.91  ? 159 TYR E CZ  1 
ATOM   15447 O OH  . TYR E 1 159 ? 36.554  38.545  49.934  1.00 52.36  ? 159 TYR E OH  1 
ATOM   15448 N N   . GLU E 1 160 ? 32.732  37.459  43.766  1.00 48.15  ? 160 GLU E N   1 
ATOM   15449 C CA  . GLU E 1 160 ? 31.428  37.166  44.330  1.00 49.60  ? 160 GLU E CA  1 
ATOM   15450 C C   . GLU E 1 160 ? 31.012  35.740  43.982  1.00 45.31  ? 160 GLU E C   1 
ATOM   15451 O O   . GLU E 1 160 ? 30.251  35.118  44.710  1.00 49.39  ? 160 GLU E O   1 
ATOM   15452 C CB  . GLU E 1 160 ? 30.369  38.174  43.905  1.00 56.48  ? 160 GLU E CB  1 
ATOM   15453 C CG  . GLU E 1 160 ? 29.284  38.268  44.969  1.00 71.74  ? 160 GLU E CG  1 
ATOM   15454 C CD  . GLU E 1 160 ? 28.039  38.968  44.498  1.00 86.05  ? 160 GLU E CD  1 
ATOM   15455 O OE1 . GLU E 1 160 ? 26.989  38.289  44.495  1.00 99.17  ? 160 GLU E OE1 1 
ATOM   15456 O OE2 . GLU E 1 160 ? 28.130  40.166  44.139  1.00 82.87  ? 160 GLU E OE2 1 
ATOM   15457 N N   . GLU E 1 161 ? 31.526  35.205  42.878  1.00 43.27  ? 161 GLU E N   1 
ATOM   15458 C CA  . GLU E 1 161 ? 31.349  33.794  42.589  1.00 47.69  ? 161 GLU E CA  1 
ATOM   15459 C C   . GLU E 1 161 ? 32.151  32.961  43.585  1.00 52.28  ? 161 GLU E C   1 
ATOM   15460 O O   . GLU E 1 161 ? 31.923  31.768  43.692  1.00 61.39  ? 161 GLU E O   1 
ATOM   15461 C CB  . GLU E 1 161 ? 31.801  33.433  41.174  1.00 53.06  ? 161 GLU E CB  1 
ATOM   15462 C CG  . GLU E 1 161 ? 30.872  33.935  40.070  1.00 54.66  ? 161 GLU E CG  1 
ATOM   15463 C CD  . GLU E 1 161 ? 31.343  33.698  38.641  1.00 55.54  ? 161 GLU E CD  1 
ATOM   15464 O OE1 . GLU E 1 161 ? 30.495  33.957  37.771  1.00 55.36  ? 161 GLU E OE1 1 
ATOM   15465 O OE2 . GLU E 1 161 ? 32.500  33.279  38.375  1.00 56.21  ? 161 GLU E OE2 1 
ATOM   15466 N N   . GLY E 1 162 ? 33.102  33.586  44.293  1.00 52.64  ? 162 GLY E N   1 
ATOM   15467 C CA  . GLY E 1 162 ? 33.966  32.885  45.230  1.00 49.11  ? 162 GLY E CA  1 
ATOM   15468 C C   . GLY E 1 162 ? 35.198  32.335  44.518  1.00 49.85  ? 162 GLY E C   1 
ATOM   15469 O O   . GLY E 1 162 ? 35.080  31.461  43.667  1.00 53.73  ? 162 GLY E O   1 
ATOM   15470 N N   . MET E 1 163 ? 36.360  32.910  44.832  1.00 48.01  ? 163 MET E N   1 
ATOM   15471 C CA  . MET E 1 163 ? 37.604  32.580  44.161  1.00 49.92  ? 163 MET E CA  1 
ATOM   15472 C C   . MET E 1 163 ? 38.742  32.681  45.173  1.00 48.88  ? 163 MET E C   1 
ATOM   15473 O O   . MET E 1 163 ? 38.729  33.558  46.037  1.00 41.45  ? 163 MET E O   1 
ATOM   15474 C CB  . MET E 1 163 ? 37.871  33.471  42.928  1.00 51.45  ? 163 MET E CB  1 
ATOM   15475 C CG  . MET E 1 163 ? 38.330  34.920  43.165  1.00 45.11  ? 163 MET E CG  1 
ATOM   15476 S SD  . MET E 1 163 ? 39.312  35.587  41.796  1.00 44.42  ? 163 MET E SD  1 
ATOM   15477 C CE  . MET E 1 163 ? 39.313  37.361  42.105  1.00 42.89  ? 163 MET E CE  1 
ATOM   15478 N N   . ARG E 1 164 ? 39.717  31.774  45.039  1.00 52.25  ? 164 ARG E N   1 
ATOM   15479 C CA  . ARG E 1 164 ? 40.845  31.711  45.953  1.00 59.38  ? 164 ARG E CA  1 
ATOM   15480 C C   . ARG E 1 164 ? 41.753  32.919  45.724  1.00 50.66  ? 164 ARG E C   1 
ATOM   15481 O O   . ARG E 1 164 ? 41.848  33.407  44.610  1.00 45.01  ? 164 ARG E O   1 
ATOM   15482 C CB  . ARG E 1 164 ? 41.541  30.363  45.742  1.00 68.82  ? 164 ARG E CB  1 
ATOM   15483 C CG  . ARG E 1 164 ? 40.677  29.191  46.190  1.00 86.96  ? 164 ARG E CG  1 
ATOM   15484 C CD  . ARG E 1 164 ? 41.036  27.891  45.477  1.00 102.61 ? 164 ARG E CD  1 
ATOM   15485 N NE  . ARG E 1 164 ? 42.485  27.665  45.412  1.00 122.93 ? 164 ARG E NE  1 
ATOM   15486 C CZ  . ARG E 1 164 ? 43.310  27.561  46.461  1.00 138.18 ? 164 ARG E CZ  1 
ATOM   15487 N NH1 . ARG E 1 164 ? 42.848  27.658  47.698  1.00 132.37 ? 164 ARG E NH1 1 
ATOM   15488 N NH2 . ARG E 1 164 ? 44.606  27.362  46.269  1.00 140.20 ? 164 ARG E NH2 1 
ATOM   15489 N N   . ARG E 1 165 ? 42.388  33.414  46.793  1.00 51.34  ? 165 ARG E N   1 
ATOM   15490 C CA  . ARG E 1 165 ? 43.343  34.509  46.698  1.00 57.80  ? 165 ARG E CA  1 
ATOM   15491 C C   . ARG E 1 165 ? 44.406  34.184  45.646  1.00 53.14  ? 165 ARG E C   1 
ATOM   15492 O O   . ARG E 1 165 ? 44.853  35.079  44.931  1.00 46.47  ? 165 ARG E O   1 
ATOM   15493 C CB  . ARG E 1 165 ? 43.949  34.820  48.073  1.00 64.32  ? 165 ARG E CB  1 
ATOM   15494 C CG  . ARG E 1 165 ? 42.922  35.396  49.041  1.00 74.06  ? 165 ARG E CG  1 
ATOM   15495 C CD  . ARG E 1 165 ? 43.104  34.917  50.475  1.00 78.15  ? 165 ARG E CD  1 
ATOM   15496 N NE  . ARG E 1 165 ? 44.315  35.499  51.068  1.00 79.84  ? 165 ARG E NE  1 
ATOM   15497 C CZ  . ARG E 1 165 ? 45.374  34.830  51.539  1.00 76.05  ? 165 ARG E CZ  1 
ATOM   15498 N NH1 . ARG E 1 165 ? 45.477  33.512  51.427  1.00 71.47  ? 165 ARG E NH1 1 
ATOM   15499 N NH2 . ARG E 1 165 ? 46.357  35.493  52.120  1.00 71.84  ? 165 ARG E NH2 1 
ATOM   15500 N N   . GLU E 1 166 ? 44.765  32.893  45.550  1.00 55.37  ? 166 GLU E N   1 
ATOM   15501 C CA  . GLU E 1 166 ? 45.782  32.372  44.643  1.00 54.26  ? 166 GLU E CA  1 
ATOM   15502 C C   . GLU E 1 166 ? 45.515  32.799  43.197  1.00 50.79  ? 166 GLU E C   1 
ATOM   15503 O O   . GLU E 1 166 ? 46.469  32.991  42.448  1.00 38.99  ? 166 GLU E O   1 
ATOM   15504 C CB  . GLU E 1 166 ? 45.892  30.850  44.817  1.00 66.39  ? 166 GLU E CB  1 
ATOM   15505 C CG  . GLU E 1 166 ? 46.641  30.367  46.073  1.00 76.34  ? 166 GLU E CG  1 
ATOM   15506 C CD  . GLU E 1 166 ? 46.017  30.367  47.490  1.00 82.03  ? 166 GLU E CD  1 
ATOM   15507 O OE1 . GLU E 1 166 ? 46.666  29.760  48.391  1.00 67.11  ? 166 GLU E OE1 1 
ATOM   15508 O OE2 . GLU E 1 166 ? 44.923  30.950  47.749  1.00 78.46  ? 166 GLU E OE2 1 
ATOM   15509 N N   . GLU E 1 167 ? 44.237  33.018  42.827  1.00 50.26  ? 167 GLU E N   1 
ATOM   15510 C CA  . GLU E 1 167 ? 43.872  33.386  41.464  1.00 47.37  ? 167 GLU E CA  1 
ATOM   15511 C C   . GLU E 1 167 ? 43.647  34.890  41.267  1.00 39.13  ? 167 GLU E C   1 
ATOM   15512 O O   . GLU E 1 167 ? 43.390  35.324  40.150  1.00 43.01  ? 167 GLU E O   1 
ATOM   15513 C CB  . GLU E 1 167 ? 42.583  32.699  41.034  1.00 57.45  ? 167 GLU E CB  1 
ATOM   15514 C CG  . GLU E 1 167 ? 42.576  31.182  41.211  1.00 68.37  ? 167 GLU E CG  1 
ATOM   15515 C CD  . GLU E 1 167 ? 41.131  30.763  41.464  1.00 87.58  ? 167 GLU E CD  1 
ATOM   15516 O OE1 . GLU E 1 167 ? 40.223  31.192  40.701  1.00 89.12  ? 167 GLU E OE1 1 
ATOM   15517 O OE2 . GLU E 1 167 ? 40.901  30.059  42.473  1.00 94.76  ? 167 GLU E OE2 1 
ATOM   15518 N N   . HIS E 1 168 ? 43.785  35.710  42.310  1.00 34.66  ? 168 HIS E N   1 
ATOM   15519 C CA  . HIS E 1 168 ? 43.599  37.156  42.200  1.00 32.89  ? 168 HIS E CA  1 
ATOM   15520 C C   . HIS E 1 168 ? 44.353  37.795  41.023  1.00 31.92  ? 168 HIS E C   1 
ATOM   15521 O O   . HIS E 1 168 ? 43.824  38.703  40.370  1.00 27.34  ? 168 HIS E O   1 
ATOM   15522 C CB  . HIS E 1 168 ? 44.001  37.866  43.498  1.00 31.97  ? 168 HIS E CB  1 
ATOM   15523 C CG  . HIS E 1 168 ? 42.979  37.741  44.582  1.00 37.40  ? 168 HIS E CG  1 
ATOM   15524 N ND1 . HIS E 1 168 ? 43.060  38.460  45.756  1.00 37.36  ? 168 HIS E ND1 1 
ATOM   15525 C CD2 . HIS E 1 168 ? 41.867  36.968  44.682  1.00 36.03  ? 168 HIS E CD2 1 
ATOM   15526 C CE1 . HIS E 1 168 ? 42.031  38.131  46.526  1.00 38.37  ? 168 HIS E CE1 1 
ATOM   15527 N NE2 . HIS E 1 168 ? 41.297  37.230  45.899  1.00 38.36  ? 168 HIS E NE2 1 
ATOM   15528 N N   . TRP E 1 169 ? 45.600  37.358  40.783  1.00 27.01  ? 169 TRP E N   1 
ATOM   15529 C CA  . TRP E 1 169 ? 46.454  38.055  39.855  1.00 26.61  ? 169 TRP E CA  1 
ATOM   15530 C C   . TRP E 1 169 ? 45.908  37.852  38.436  1.00 28.55  ? 169 TRP E C   1 
ATOM   15531 O O   . TRP E 1 169 ? 45.939  38.766  37.613  1.00 29.43  ? 169 TRP E O   1 
ATOM   15532 C CB  . TRP E 1 169 ? 47.916  37.601  40.060  1.00 28.78  ? 169 TRP E CB  1 
ATOM   15533 C CG  . TRP E 1 169 ? 48.201  36.190  39.616  1.00 28.58  ? 169 TRP E CG  1 
ATOM   15534 C CD1 . TRP E 1 169 ? 48.188  35.071  40.391  1.00 29.06  ? 169 TRP E CD1 1 
ATOM   15535 C CD2 . TRP E 1 169 ? 48.478  35.734  38.268  1.00 28.90  ? 169 TRP E CD2 1 
ATOM   15536 N NE1 . TRP E 1 169 ? 48.458  33.962  39.627  1.00 29.05  ? 169 TRP E NE1 1 
ATOM   15537 C CE2 . TRP E 1 169 ? 48.643  34.337  38.327  1.00 28.79  ? 169 TRP E CE2 1 
ATOM   15538 C CE3 . TRP E 1 169 ? 48.629  36.363  37.033  1.00 28.31  ? 169 TRP E CE3 1 
ATOM   15539 C CZ2 . TRP E 1 169 ? 48.951  33.574  37.208  1.00 29.49  ? 169 TRP E CZ2 1 
ATOM   15540 C CZ3 . TRP E 1 169 ? 48.942  35.604  35.924  1.00 29.64  ? 169 TRP E CZ3 1 
ATOM   15541 C CH2 . TRP E 1 169 ? 49.090  34.226  36.006  1.00 27.39  ? 169 TRP E CH2 1 
ATOM   15542 N N   . GLU E 1 170 ? 45.319  36.674  38.180  1.00 29.98  ? 170 GLU E N   1 
ATOM   15543 C CA  . GLU E 1 170 ? 44.775  36.322  36.875  1.00 31.07  ? 170 GLU E CA  1 
ATOM   15544 C C   . GLU E 1 170 ? 43.602  37.231  36.473  1.00 33.54  ? 170 GLU E C   1 
ATOM   15545 O O   . GLU E 1 170 ? 43.500  37.663  35.312  1.00 31.81  ? 170 GLU E O   1 
ATOM   15546 C CB  . GLU E 1 170 ? 44.331  34.860  36.904  1.00 34.32  ? 170 GLU E CB  1 
ATOM   15547 C CG  . GLU E 1 170 ? 45.443  33.864  37.238  1.00 39.98  ? 170 GLU E CG  1 
ATOM   15548 C CD  . GLU E 1 170 ? 45.044  32.400  37.153  1.00 41.82  ? 170 GLU E CD  1 
ATOM   15549 O OE1 . GLU E 1 170 ? 45.259  31.656  38.131  1.00 51.04  ? 170 GLU E OE1 1 
ATOM   15550 O OE2 . GLU E 1 170 ? 44.504  32.015  36.102  1.00 39.36  ? 170 GLU E OE2 1 
ATOM   15551 N N   . ALA E 1 171 ? 42.699  37.486  37.433  1.00 31.53  ? 171 ALA E N   1 
ATOM   15552 C CA  . ALA E 1 171 ? 41.556  38.363  37.229  1.00 31.93  ? 171 ALA E CA  1 
ATOM   15553 C C   . ALA E 1 171 ? 42.000  39.808  37.076  1.00 29.66  ? 171 ALA E C   1 
ATOM   15554 O O   . ALA E 1 171 ? 41.411  40.561  36.309  1.00 26.28  ? 171 ALA E O   1 
ATOM   15555 C CB  . ALA E 1 171 ? 40.607  38.259  38.395  1.00 35.21  ? 171 ALA E CB  1 
ATOM   15556 N N   . MET E 1 172 ? 42.988  40.184  37.890  1.00 28.84  ? 172 MET E N   1 
ATOM   15557 C CA  . MET E 1 172 ? 43.598  41.497  37.831  1.00 30.33  ? 172 MET E CA  1 
ATOM   15558 C C   . MET E 1 172 ? 44.228  41.711  36.447  1.00 32.90  ? 172 MET E C   1 
ATOM   15559 O O   . MET E 1 172 ? 44.188  42.814  35.893  1.00 27.87  ? 172 MET E O   1 
ATOM   15560 C CB  . MET E 1 172 ? 44.645  41.607  38.948  1.00 30.86  ? 172 MET E CB  1 
ATOM   15561 C CG  . MET E 1 172 ? 44.057  41.895  40.313  1.00 32.19  ? 172 MET E CG  1 
ATOM   15562 S SD  . MET E 1 172 ? 43.430  43.585  40.398  1.00 32.79  ? 172 MET E SD  1 
ATOM   15563 C CE  . MET E 1 172 ? 42.810  43.395  42.061  1.00 46.23  ? 172 MET E CE  1 
ATOM   15564 N N   . LEU E 1 173 ? 44.820  40.635  35.896  1.00 34.14  ? 173 LEU E N   1 
ATOM   15565 C CA  . LEU E 1 173 ? 45.516  40.706  34.616  1.00 32.52  ? 173 LEU E CA  1 
ATOM   15566 C C   . LEU E 1 173 ? 44.485  40.909  33.508  1.00 30.81  ? 173 LEU E C   1 
ATOM   15567 O O   . LEU E 1 173 ? 44.605  41.829  32.687  1.00 33.55  ? 173 LEU E O   1 
ATOM   15568 C CB  . LEU E 1 173 ? 46.387  39.472  34.359  1.00 29.82  ? 173 LEU E CB  1 
ATOM   15569 C CG  . LEU E 1 173 ? 47.040  39.390  32.970  1.00 31.60  ? 173 LEU E CG  1 
ATOM   15570 C CD1 . LEU E 1 173 ? 47.990  40.588  32.767  1.00 32.73  ? 173 LEU E CD1 1 
ATOM   15571 C CD2 . LEU E 1 173 ? 47.763  38.071  32.664  1.00 29.85  ? 173 LEU E CD2 1 
ATOM   15572 N N   . GLU E 1 174 ? 43.454  40.059  33.535  1.00 28.13  ? 174 GLU E N   1 
ATOM   15573 C CA  . GLU E 1 174 ? 42.352  40.137  32.594  1.00 26.08  ? 174 GLU E CA  1 
ATOM   15574 C C   . GLU E 1 174 ? 41.718  41.529  32.574  1.00 24.96  ? 174 GLU E C   1 
ATOM   15575 O O   . GLU E 1 174 ? 41.553  42.147  31.517  1.00 28.22  ? 174 GLU E O   1 
ATOM   15576 C CB  . GLU E 1 174 ? 41.390  39.032  32.977  1.00 29.54  ? 174 GLU E CB  1 
ATOM   15577 C CG  . GLU E 1 174 ? 40.354  38.824  31.883  1.00 36.55  ? 174 GLU E CG  1 
ATOM   15578 C CD  . GLU E 1 174 ? 40.886  38.358  30.540  1.00 35.66  ? 174 GLU E CD  1 
ATOM   15579 O OE1 . GLU E 1 174 ? 42.052  37.903  30.420  1.00 32.62  ? 174 GLU E OE1 1 
ATOM   15580 O OE2 . GLU E 1 174 ? 40.039  38.431  29.619  1.00 34.76  ? 174 GLU E OE2 1 
ATOM   15581 N N   . ASP E 1 175 ? 41.370  42.051  33.741  1.00 23.86  ? 175 ASP E N   1 
ATOM   15582 C CA  . ASP E 1 175 ? 40.803  43.385  33.805  1.00 27.12  ? 175 ASP E CA  1 
ATOM   15583 C C   . ASP E 1 175 ? 41.807  44.430  33.311  1.00 28.18  ? 175 ASP E C   1 
ATOM   15584 O O   . ASP E 1 175 ? 41.430  45.419  32.664  1.00 27.83  ? 175 ASP E O   1 
ATOM   15585 C CB  . ASP E 1 175 ? 40.277  43.694  35.201  1.00 28.57  ? 175 ASP E CB  1 
ATOM   15586 C CG  . ASP E 1 175 ? 38.911  43.114  35.571  1.00 28.50  ? 175 ASP E CG  1 
ATOM   15587 O OD1 . ASP E 1 175 ? 38.100  42.824  34.653  1.00 25.12  ? 175 ASP E OD1 1 
ATOM   15588 O OD2 . ASP E 1 175 ? 38.668  42.939  36.793  1.00 32.86  ? 175 ASP E OD2 1 
ATOM   15589 N N   . SER E 1 176 ? 43.082  44.222  33.652  1.00 27.72  ? 176 SER E N   1 
ATOM   15590 C CA  . SER E 1 176 ? 44.115  45.164  33.285  1.00 28.72  ? 176 SER E CA  1 
ATOM   15591 C C   . SER E 1 176 ? 44.256  45.256  31.749  1.00 30.49  ? 176 SER E C   1 
ATOM   15592 O O   . SER E 1 176 ? 44.398  46.348  31.176  1.00 28.55  ? 176 SER E O   1 
ATOM   15593 C CB  . SER E 1 176 ? 45.395  44.823  34.014  1.00 29.06  ? 176 SER E CB  1 
ATOM   15594 O OG  . SER E 1 176 ? 45.312  45.139  35.404  1.00 27.28  ? 176 SER E OG  1 
ATOM   15595 N N   . LEU E 1 177 ? 44.137  44.126  31.043  1.00 28.50  ? 177 LEU E N   1 
ATOM   15596 C CA  . LEU E 1 177 ? 44.170  44.151  29.583  1.00 25.31  ? 177 LEU E CA  1 
ATOM   15597 C C   . LEU E 1 177 ? 42.958  44.892  29.039  1.00 27.05  ? 177 LEU E C   1 
ATOM   15598 O O   . LEU E 1 177 ? 43.091  45.658  28.101  1.00 27.30  ? 177 LEU E O   1 
ATOM   15599 C CB  . LEU E 1 177 ? 44.183  42.728  29.045  1.00 24.79  ? 177 LEU E CB  1 
ATOM   15600 C CG  . LEU E 1 177 ? 45.399  41.865  29.385  1.00 24.80  ? 177 LEU E CG  1 
ATOM   15601 C CD1 . LEU E 1 177 ? 45.117  40.383  29.148  1.00 25.90  ? 177 LEU E CD1 1 
ATOM   15602 C CD2 . LEU E 1 177 ? 46.565  42.303  28.543  1.00 24.03  ? 177 LEU E CD2 1 
ATOM   15603 N N   . ASN E 1 178 ? 41.768  44.639  29.602  1.00 29.95  ? 178 ASN E N   1 
ATOM   15604 C CA  . ASN E 1 178 ? 40.557  45.292  29.110  1.00 31.73  ? 178 ASN E CA  1 
ATOM   15605 C C   . ASN E 1 178 ? 40.647  46.800  29.316  1.00 31.05  ? 178 ASN E C   1 
ATOM   15606 O O   . ASN E 1 178 ? 40.371  47.575  28.402  1.00 30.55  ? 178 ASN E O   1 
ATOM   15607 C CB  . ASN E 1 178 ? 39.290  44.736  29.760  1.00 32.29  ? 178 ASN E CB  1 
ATOM   15608 C CG  . ASN E 1 178 ? 39.007  43.327  29.290  1.00 32.05  ? 178 ASN E CG  1 
ATOM   15609 O OD1 . ASN E 1 178 ? 39.474  42.926  28.215  1.00 28.06  ? 178 ASN E OD1 1 
ATOM   15610 N ND2 . ASN E 1 178 ? 38.243  42.570  30.066  1.00 27.90  ? 178 ASN E ND2 1 
ATOM   15611 N N   . MET E 1 179 ? 41.044  47.207  30.530  1.00 31.40  ? 179 MET E N   1 
ATOM   15612 C CA  . MET E 1 179 ? 41.048  48.617  30.888  1.00 28.65  ? 179 MET E CA  1 
ATOM   15613 C C   . MET E 1 179 ? 42.090  49.360  30.062  1.00 29.34  ? 179 MET E C   1 
ATOM   15614 O O   . MET E 1 179 ? 41.804  50.411  29.489  1.00 35.97  ? 179 MET E O   1 
ATOM   15615 C CB  . MET E 1 179 ? 41.312  48.823  32.384  1.00 28.29  ? 179 MET E CB  1 
ATOM   15616 C CG  . MET E 1 179 ? 41.009  50.242  32.817  1.00 27.38  ? 179 MET E CG  1 
ATOM   15617 S SD  . MET E 1 179 ? 41.546  50.669  34.479  1.00 27.40  ? 179 MET E SD  1 
ATOM   15618 C CE  . MET E 1 179 ? 43.341  50.623  34.321  1.00 27.81  ? 179 MET E CE  1 
ATOM   15619 N N   . LEU E 1 180 ? 43.305  48.810  30.000  1.00 28.94  ? 180 LEU E N   1 
ATOM   15620 C CA  . LEU E 1 180 ? 44.384  49.471  29.288  1.00 28.66  ? 180 LEU E CA  1 
ATOM   15621 C C   . LEU E 1 180 ? 43.969  49.670  27.830  1.00 29.33  ? 180 LEU E C   1 
ATOM   15622 O O   . LEU E 1 180 ? 44.160  50.753  27.272  1.00 24.99  ? 180 LEU E O   1 
ATOM   15623 C CB  . LEU E 1 180 ? 45.656  48.639  29.406  1.00 30.41  ? 180 LEU E CB  1 
ATOM   15624 C CG  . LEU E 1 180 ? 46.393  48.730  30.742  1.00 28.09  ? 180 LEU E CG  1 
ATOM   15625 C CD1 . LEU E 1 180 ? 47.530  47.720  30.721  1.00 27.59  ? 180 LEU E CD1 1 
ATOM   15626 C CD2 . LEU E 1 180 ? 46.875  50.167  30.958  1.00 27.13  ? 180 LEU E CD2 1 
ATOM   15627 N N   . ALA E 1 181 ? 43.380  48.622  27.227  1.00 25.86  ? 181 ALA E N   1 
ATOM   15628 C CA  . ALA E 1 181 ? 42.849  48.755  25.878  1.00 25.23  ? 181 ALA E CA  1 
ATOM   15629 C C   . ALA E 1 181 ? 41.842  49.907  25.818  1.00 26.99  ? 181 ALA E C   1 
ATOM   15630 O O   . ALA E 1 181 ? 41.846  50.661  24.856  1.00 30.48  ? 181 ALA E O   1 
ATOM   15631 C CB  . ALA E 1 181 ? 42.223  47.449  25.422  1.00 24.97  ? 181 ALA E CB  1 
ATOM   15632 N N   . ALA E 1 182 ? 40.997  50.064  26.846  1.00 25.42  ? 182 ALA E N   1 
ATOM   15633 C CA  . ALA E 1 182 ? 39.962  51.083  26.816  1.00 26.75  ? 182 ALA E CA  1 
ATOM   15634 C C   . ALA E 1 182 ? 40.500  52.510  27.023  1.00 26.65  ? 182 ALA E C   1 
ATOM   15635 O O   . ALA E 1 182 ? 39.837  53.483  26.653  1.00 25.67  ? 182 ALA E O   1 
ATOM   15636 C CB  . ALA E 1 182 ? 38.906  50.745  27.846  1.00 26.57  ? 182 ALA E CB  1 
ATOM   15637 N N   . LEU E 1 183 ? 41.670  52.672  27.648  1.00 25.57  ? 183 LEU E N   1 
ATOM   15638 C CA  . LEU E 1 183 ? 42.038  54.000  28.115  1.00 26.30  ? 183 LEU E CA  1 
ATOM   15639 C C   . LEU E 1 183 ? 42.178  54.952  26.939  1.00 24.17  ? 183 LEU E C   1 
ATOM   15640 O O   . LEU E 1 183 ? 41.734  56.101  27.024  1.00 23.40  ? 183 LEU E O   1 
ATOM   15641 C CB  . LEU E 1 183 ? 43.294  54.043  28.979  1.00 27.00  ? 183 LEU E CB  1 
ATOM   15642 C CG  . LEU E 1 183 ? 43.193  53.350  30.336  1.00 32.58  ? 183 LEU E CG  1 
ATOM   15643 C CD1 . LEU E 1 183 ? 44.476  53.485  31.124  1.00 32.97  ? 183 LEU E CD1 1 
ATOM   15644 C CD2 . LEU E 1 183 ? 42.047  53.918  31.155  1.00 39.98  ? 183 LEU E CD2 1 
ATOM   15645 N N   . PRO E 1 184 ? 42.874  54.541  25.858  1.00 24.89  ? 184 PRO E N   1 
ATOM   15646 C CA  . PRO E 1 184 ? 43.047  55.397  24.673  1.00 25.07  ? 184 PRO E CA  1 
ATOM   15647 C C   . PRO E 1 184 ? 41.720  55.824  24.049  1.00 22.68  ? 184 PRO E C   1 
ATOM   15648 O O   . PRO E 1 184 ? 41.575  56.965  23.624  1.00 23.02  ? 184 PRO E O   1 
ATOM   15649 C CB  . PRO E 1 184 ? 43.887  54.559  23.706  1.00 23.09  ? 184 PRO E CB  1 
ATOM   15650 C CG  . PRO E 1 184 ? 44.531  53.527  24.596  1.00 24.88  ? 184 PRO E CG  1 
ATOM   15651 C CD  . PRO E 1 184 ? 43.591  53.266  25.740  1.00 23.91  ? 184 PRO E CD  1 
ATOM   15652 N N   . VAL E 1 185 ? 40.742  54.915  24.054  1.00 23.37  ? 185 VAL E N   1 
ATOM   15653 C CA  . VAL E 1 185 ? 39.438  55.163  23.452  1.00 24.29  ? 185 VAL E CA  1 
ATOM   15654 C C   . VAL E 1 185 ? 38.694  56.227  24.275  1.00 22.76  ? 185 VAL E C   1 
ATOM   15655 O O   . VAL E 1 185 ? 38.183  57.198  23.704  1.00 19.80  ? 185 VAL E O   1 
ATOM   15656 C CB  . VAL E 1 185 ? 38.642  53.844  23.325  1.00 27.08  ? 185 VAL E CB  1 
ATOM   15657 C CG1 . VAL E 1 185 ? 37.277  54.026  22.680  1.00 27.04  ? 185 VAL E CG1 1 
ATOM   15658 C CG2 . VAL E 1 185 ? 39.411  52.768  22.562  1.00 29.42  ? 185 VAL E CG2 1 
ATOM   15659 N N   . ILE E 1 186 ? 38.705  56.068  25.612  1.00 20.53  ? 186 ILE E N   1 
ATOM   15660 C CA  . ILE E 1 186 ? 38.034  56.989  26.513  1.00 21.19  ? 186 ILE E CA  1 
ATOM   15661 C C   . ILE E 1 186 ? 38.720  58.347  26.395  1.00 23.10  ? 186 ILE E C   1 
ATOM   15662 O O   . ILE E 1 186 ? 38.052  59.375  26.222  1.00 31.86  ? 186 ILE E O   1 
ATOM   15663 C CB  . ILE E 1 186 ? 38.029  56.449  27.961  1.00 21.03  ? 186 ILE E CB  1 
ATOM   15664 C CG1 . ILE E 1 186 ? 37.142  55.214  28.104  1.00 21.29  ? 186 ILE E CG1 1 
ATOM   15665 C CG2 . ILE E 1 186 ? 37.662  57.526  28.983  1.00 18.92  ? 186 ILE E CG2 1 
ATOM   15666 C CD1 . ILE E 1 186 ? 37.318  54.479  29.417  1.00 21.25  ? 186 ILE E CD1 1 
ATOM   15667 N N   . ALA E 1 187 ? 40.051  58.353  26.461  1.00 21.67  ? 187 ALA E N   1 
ATOM   15668 C CA  . ALA E 1 187 ? 40.818  59.595  26.405  1.00 21.22  ? 187 ALA E CA  1 
ATOM   15669 C C   . ALA E 1 187 ? 40.592  60.326  25.077  1.00 21.95  ? 187 ALA E C   1 
ATOM   15670 O O   . ALA E 1 187 ? 40.412  61.528  25.046  1.00 21.58  ? 187 ALA E O   1 
ATOM   15671 C CB  . ALA E 1 187 ? 42.273  59.232  26.596  1.00 21.77  ? 187 ALA E CB  1 
ATOM   15672 N N   . ALA E 1 188 ? 40.637  59.586  23.964  1.00 22.19  ? 188 ALA E N   1 
ATOM   15673 C CA  . ALA E 1 188 ? 40.379  60.143  22.650  1.00 23.88  ? 188 ALA E CA  1 
ATOM   15674 C C   . ALA E 1 188 ? 38.978  60.737  22.594  1.00 25.23  ? 188 ALA E C   1 
ATOM   15675 O O   . ALA E 1 188 ? 38.839  61.885  22.148  1.00 25.69  ? 188 ALA E O   1 
ATOM   15676 C CB  . ALA E 1 188 ? 40.556  59.099  21.575  1.00 21.93  ? 188 ALA E CB  1 
ATOM   15677 N N   . TYR E 1 189 ? 37.976  59.965  23.063  1.00 23.54  ? 189 TYR E N   1 
ATOM   15678 C CA  . TYR E 1 189 ? 36.588  60.405  23.014  1.00 26.03  ? 189 TYR E CA  1 
ATOM   15679 C C   . TYR E 1 189 ? 36.475  61.782  23.676  1.00 25.32  ? 189 TYR E C   1 
ATOM   15680 O O   . TYR E 1 189 ? 35.899  62.704  23.105  1.00 23.93  ? 189 TYR E O   1 
ATOM   15681 C CB  . TYR E 1 189 ? 35.642  59.350  23.617  1.00 28.64  ? 189 TYR E CB  1 
ATOM   15682 C CG  . TYR E 1 189 ? 34.169  59.671  23.411  1.00 29.08  ? 189 TYR E CG  1 
ATOM   15683 C CD1 . TYR E 1 189 ? 33.525  60.608  24.209  1.00 31.45  ? 189 TYR E CD1 1 
ATOM   15684 C CD2 . TYR E 1 189 ? 33.441  59.127  22.359  1.00 32.27  ? 189 TYR E CD2 1 
ATOM   15685 C CE1 . TYR E 1 189 ? 32.197  60.948  24.003  1.00 31.13  ? 189 TYR E CE1 1 
ATOM   15686 C CE2 . TYR E 1 189 ? 32.116  59.468  22.130  1.00 30.13  ? 189 TYR E CE2 1 
ATOM   15687 C CZ  . TYR E 1 189 ? 31.497  60.393  22.951  1.00 30.88  ? 189 TYR E CZ  1 
ATOM   15688 O OH  . TYR E 1 189 ? 30.179  60.715  22.798  1.00 35.16  ? 189 TYR E OH  1 
ATOM   15689 N N   . ILE E 1 190 ? 37.115  61.934  24.845  1.00 24.69  ? 190 ILE E N   1 
ATOM   15690 C CA  . ILE E 1 190 ? 37.122  63.181  25.590  1.00 22.78  ? 190 ILE E CA  1 
ATOM   15691 C C   . ILE E 1 190 ? 37.778  64.296  24.791  1.00 23.41  ? 190 ILE E C   1 
ATOM   15692 O O   . ILE E 1 190 ? 37.306  65.437  24.787  1.00 23.86  ? 190 ILE E O   1 
ATOM   15693 C CB  . ILE E 1 190 ? 37.809  62.991  26.953  1.00 23.06  ? 190 ILE E CB  1 
ATOM   15694 C CG1 . ILE E 1 190 ? 36.957  62.150  27.896  1.00 22.43  ? 190 ILE E CG1 1 
ATOM   15695 C CG2 . ILE E 1 190 ? 38.151  64.346  27.572  1.00 23.59  ? 190 ILE E CG2 1 
ATOM   15696 C CD1 . ILE E 1 190 ? 37.753  61.548  29.041  1.00 22.80  ? 190 ILE E CD1 1 
ATOM   15697 N N   . TYR E 1 191 ? 38.907  63.975  24.161  1.00 24.34  ? 191 TYR E N   1 
ATOM   15698 C CA  . TYR E 1 191 ? 39.651  64.959  23.387  1.00 24.54  ? 191 TYR E CA  1 
ATOM   15699 C C   . TYR E 1 191 ? 38.805  65.448  22.204  1.00 24.38  ? 191 TYR E C   1 
ATOM   15700 O O   . TYR E 1 191 ? 38.725  66.647  21.920  1.00 20.85  ? 191 TYR E O   1 
ATOM   15701 C CB  . TYR E 1 191 ? 40.988  64.333  22.953  1.00 24.03  ? 191 TYR E CB  1 
ATOM   15702 C CG  . TYR E 1 191 ? 41.954  65.312  22.307  1.00 22.48  ? 191 TYR E CG  1 
ATOM   15703 C CD1 . TYR E 1 191 ? 42.673  66.204  23.085  1.00 22.26  ? 191 TYR E CD1 1 
ATOM   15704 C CD2 . TYR E 1 191 ? 42.098  65.395  20.922  1.00 20.13  ? 191 TYR E CD2 1 
ATOM   15705 C CE1 . TYR E 1 191 ? 43.509  67.151  22.511  1.00 22.82  ? 191 TYR E CE1 1 
ATOM   15706 C CE2 . TYR E 1 191 ? 42.947  66.326  20.339  1.00 19.18  ? 191 TYR E CE2 1 
ATOM   15707 C CZ  . TYR E 1 191 ? 43.668  67.193  21.137  1.00 20.40  ? 191 TYR E CZ  1 
ATOM   15708 O OH  . TYR E 1 191 ? 44.541  68.099  20.633  1.00 19.50  ? 191 TYR E OH  1 
ATOM   15709 N N   . ARG E 1 192 ? 38.191  64.498  21.494  1.00 25.49  ? 192 ARG E N   1 
ATOM   15710 C CA  . ARG E 1 192 ? 37.479  64.843  20.276  1.00 24.61  ? 192 ARG E CA  1 
ATOM   15711 C C   . ARG E 1 192 ? 36.259  65.701  20.625  1.00 26.61  ? 192 ARG E C   1 
ATOM   15712 O O   . ARG E 1 192 ? 36.033  66.728  19.994  1.00 28.42  ? 192 ARG E O   1 
ATOM   15713 C CB  . ARG E 1 192 ? 37.119  63.574  19.510  1.00 24.68  ? 192 ARG E CB  1 
ATOM   15714 C CG  . ARG E 1 192 ? 38.279  62.741  18.984  1.00 26.60  ? 192 ARG E CG  1 
ATOM   15715 C CD  . ARG E 1 192 ? 39.229  63.516  18.114  1.00 27.90  ? 192 ARG E CD  1 
ATOM   15716 N NE  . ARG E 1 192 ? 38.521  63.936  16.901  1.00 28.29  ? 192 ARG E NE  1 
ATOM   15717 C CZ  . ARG E 1 192 ? 39.065  64.586  15.875  1.00 31.63  ? 192 ARG E CZ  1 
ATOM   15718 N NH1 . ARG E 1 192 ? 40.362  64.848  15.809  1.00 34.28  ? 192 ARG E NH1 1 
ATOM   15719 N NH2 . ARG E 1 192 ? 38.298  64.931  14.868  1.00 34.13  ? 192 ARG E NH2 1 
ATOM   15720 N N   . ARG E 1 193 ? 35.528  65.323  21.679  1.00 27.41  ? 193 ARG E N   1 
ATOM   15721 C CA  . ARG E 1 193 ? 34.315  66.018  22.092  1.00 28.30  ? 193 ARG E CA  1 
ATOM   15722 C C   . ARG E 1 193 ? 34.621  67.417  22.620  1.00 27.35  ? 193 ARG E C   1 
ATOM   15723 O O   . ARG E 1 193 ? 33.878  68.359  22.371  1.00 31.49  ? 193 ARG E O   1 
ATOM   15724 C CB  . ARG E 1 193 ? 33.578  65.250  23.201  1.00 29.08  ? 193 ARG E CB  1 
ATOM   15725 C CG  . ARG E 1 193 ? 32.205  65.843  23.502  1.00 30.35  ? 193 ARG E CG  1 
ATOM   15726 C CD  . ARG E 1 193 ? 31.342  64.956  24.412  1.00 31.45  ? 193 ARG E CD  1 
ATOM   15727 N NE  . ARG E 1 193 ? 30.102  65.636  24.808  1.00 30.60  ? 193 ARG E NE  1 
ATOM   15728 C CZ  . ARG E 1 193 ? 29.754  65.970  26.042  1.00 31.21  ? 193 ARG E CZ  1 
ATOM   15729 N NH1 . ARG E 1 193 ? 30.409  65.483  27.076  1.00 30.25  ? 193 ARG E NH1 1 
ATOM   15730 N NH2 . ARG E 1 193 ? 28.716  66.767  26.244  1.00 35.52  ? 193 ARG E NH2 1 
ATOM   15731 N N   . LYS E 1 194 ? 35.704  67.563  23.371  1.00 25.75  ? 194 LYS E N   1 
ATOM   15732 C CA  . LYS E 1 194 ? 35.954  68.843  24.000  1.00 27.64  ? 194 LYS E CA  1 
ATOM   15733 C C   . LYS E 1 194 ? 36.591  69.821  23.015  1.00 25.11  ? 194 LYS E C   1 
ATOM   15734 O O   . LYS E 1 194 ? 36.263  71.001  23.045  1.00 22.62  ? 194 LYS E O   1 
ATOM   15735 C CB  . LYS E 1 194 ? 36.823  68.760  25.260  1.00 27.71  ? 194 LYS E CB  1 
ATOM   15736 C CG  . LYS E 1 194 ? 36.197  68.156  26.502  1.00 29.29  ? 194 LYS E CG  1 
ATOM   15737 C CD  . LYS E 1 194 ? 37.126  68.168  27.722  1.00 28.51  ? 194 LYS E CD  1 
ATOM   15738 C CE  . LYS E 1 194 ? 37.381  69.555  28.211  1.00 26.99  ? 194 LYS E CE  1 
ATOM   15739 N NZ  . LYS E 1 194 ? 36.228  70.183  28.873  1.00 25.66  ? 194 LYS E NZ  1 
ATOM   15740 N N   . TYR E 1 195 ? 37.547  69.339  22.210  1.00 26.50  ? 195 TYR E N   1 
ATOM   15741 C CA  . TYR E 1 195 ? 38.515  70.207  21.555  1.00 24.99  ? 195 TYR E CA  1 
ATOM   15742 C C   . TYR E 1 195 ? 38.458  70.113  20.033  1.00 25.88  ? 195 TYR E C   1 
ATOM   15743 O O   . TYR E 1 195 ? 39.001  70.994  19.357  1.00 25.85  ? 195 TYR E O   1 
ATOM   15744 C CB  . TYR E 1 195 ? 39.915  69.843  22.058  1.00 23.56  ? 195 TYR E CB  1 
ATOM   15745 C CG  . TYR E 1 195 ? 40.088  69.835  23.573  1.00 22.48  ? 195 TYR E CG  1 
ATOM   15746 C CD1 . TYR E 1 195 ? 39.929  70.986  24.340  1.00 21.55  ? 195 TYR E CD1 1 
ATOM   15747 C CD2 . TYR E 1 195 ? 40.470  68.673  24.231  1.00 22.59  ? 195 TYR E CD2 1 
ATOM   15748 C CE1 . TYR E 1 195 ? 40.098  70.963  25.717  1.00 22.41  ? 195 TYR E CE1 1 
ATOM   15749 C CE2 . TYR E 1 195 ? 40.662  68.643  25.604  1.00 22.96  ? 195 TYR E CE2 1 
ATOM   15750 C CZ  . TYR E 1 195 ? 40.479  69.789  26.352  1.00 22.27  ? 195 TYR E CZ  1 
ATOM   15751 O OH  . TYR E 1 195 ? 40.659  69.678  27.705  1.00 23.29  ? 195 TYR E OH  1 
ATOM   15752 N N   . LYS E 1 196 ? 37.838  69.061  19.484  1.00 26.74  ? 196 LYS E N   1 
ATOM   15753 C CA  . LYS E 1 196 ? 37.954  68.843  18.046  1.00 33.06  ? 196 LYS E CA  1 
ATOM   15754 C C   . LYS E 1 196 ? 36.589  68.694  17.377  1.00 31.71  ? 196 LYS E C   1 
ATOM   15755 O O   . LYS E 1 196 ? 36.456  67.888  16.472  1.00 33.96  ? 196 LYS E O   1 
ATOM   15756 C CB  . LYS E 1 196 ? 38.820  67.610  17.749  1.00 34.40  ? 196 LYS E CB  1 
ATOM   15757 C CG  . LYS E 1 196 ? 40.269  67.744  18.168  1.00 33.99  ? 196 LYS E CG  1 
ATOM   15758 C CD  . LYS E 1 196 ? 41.001  68.844  17.410  1.00 33.58  ? 196 LYS E CD  1 
ATOM   15759 C CE  . LYS E 1 196 ? 42.498  68.946  17.605  1.00 33.52  ? 196 LYS E CE  1 
ATOM   15760 N NZ  . LYS E 1 196 ? 42.959  70.330  17.375  1.00 31.82  ? 196 LYS E NZ  1 
ATOM   15761 N N   . GLY E 1 197 ? 35.585  69.451  17.836  1.00 29.96  ? 197 GLY E N   1 
ATOM   15762 C CA  . GLY E 1 197 ? 34.291  69.513  17.183  1.00 28.86  ? 197 GLY E CA  1 
ATOM   15763 C C   . GLY E 1 197 ? 33.503  68.200  17.199  1.00 28.94  ? 197 GLY E C   1 
ATOM   15764 O O   . GLY E 1 197 ? 32.665  67.966  16.336  1.00 33.44  ? 197 GLY E O   1 
ATOM   15765 N N   . ASP E 1 198 ? 33.721  67.354  18.193  1.00 27.84  ? 198 ASP E N   1 
ATOM   15766 C CA  . ASP E 1 198 ? 32.809  66.257  18.483  1.00 27.82  ? 198 ASP E CA  1 
ATOM   15767 C C   . ASP E 1 198 ? 32.675  65.327  17.284  1.00 26.54  ? 198 ASP E C   1 
ATOM   15768 O O   . ASP E 1 198 ? 31.605  64.833  16.989  1.00 28.03  ? 198 ASP E O   1 
ATOM   15769 C CB  . ASP E 1 198 ? 31.458  66.774  18.962  1.00 28.31  ? 198 ASP E CB  1 
ATOM   15770 C CG  . ASP E 1 198 ? 30.619  65.760  19.724  1.00 28.90  ? 198 ASP E CG  1 
ATOM   15771 O OD1 . ASP E 1 198 ? 31.188  64.712  20.116  1.00 30.00  ? 198 ASP E OD1 1 
ATOM   15772 O OD2 . ASP E 1 198 ? 29.405  66.001  19.873  1.00 26.79  ? 198 ASP E OD2 1 
ATOM   15773 N N   . THR E 1 199 ? 33.795  65.070  16.625  1.00 30.51  ? 199 THR E N   1 
ATOM   15774 C CA  . THR E 1 199 ? 33.911  64.138  15.515  1.00 31.00  ? 199 THR E CA  1 
ATOM   15775 C C   . THR E 1 199 ? 34.752  62.966  16.019  1.00 27.92  ? 199 THR E C   1 
ATOM   15776 O O   . THR E 1 199 ? 35.718  63.182  16.721  1.00 25.38  ? 199 THR E O   1 
ATOM   15777 C CB  . THR E 1 199 ? 34.553  64.960  14.389  1.00 37.84  ? 199 THR E CB  1 
ATOM   15778 O OG1 . THR E 1 199 ? 33.466  65.738  13.883  1.00 37.30  ? 199 THR E OG1 1 
ATOM   15779 C CG2 . THR E 1 199 ? 35.204  64.135  13.293  1.00 44.09  ? 199 THR E CG2 1 
ATOM   15780 N N   . HIS E 1 200 ? 34.409  61.722  15.692  1.00 30.90  ? 200 HIS E N   1 
ATOM   15781 C CA  . HIS E 1 200 ? 34.991  60.589  16.402  1.00 33.60  ? 200 HIS E CA  1 
ATOM   15782 C C   . HIS E 1 200 ? 35.725  59.650  15.446  1.00 34.89  ? 200 HIS E C   1 
ATOM   15783 O O   . HIS E 1 200 ? 35.150  59.162  14.481  1.00 37.39  ? 200 HIS E O   1 
ATOM   15784 C CB  . HIS E 1 200 ? 33.914  59.948  17.291  1.00 33.55  ? 200 HIS E CB  1 
ATOM   15785 C CG  . HIS E 1 200 ? 33.496  60.925  18.359  1.00 33.54  ? 200 HIS E CG  1 
ATOM   15786 N ND1 . HIS E 1 200 ? 34.153  61.056  19.566  1.00 30.68  ? 200 HIS E ND1 1 
ATOM   15787 C CD2 . HIS E 1 200 ? 32.553  61.889  18.337  1.00 30.22  ? 200 HIS E CD2 1 
ATOM   15788 C CE1 . HIS E 1 200 ? 33.586  62.049  20.242  1.00 33.61  ? 200 HIS E CE1 1 
ATOM   15789 N NE2 . HIS E 1 200 ? 32.623  62.578  19.506  1.00 30.35  ? 200 HIS E NE2 1 
ATOM   15790 N N   . ILE E 1 201 ? 36.999  59.378  15.757  1.00 33.34  ? 201 ILE E N   1 
ATOM   15791 C CA  . ILE E 1 201 ? 37.869  58.554  14.932  1.00 29.77  ? 201 ILE E CA  1 
ATOM   15792 C C   . ILE E 1 201 ? 38.073  57.210  15.613  1.00 32.13  ? 201 ILE E C   1 
ATOM   15793 O O   . ILE E 1 201 ? 38.510  57.141  16.758  1.00 35.32  ? 201 ILE E O   1 
ATOM   15794 C CB  . ILE E 1 201 ? 39.221  59.248  14.693  1.00 30.05  ? 201 ILE E CB  1 
ATOM   15795 C CG1 . ILE E 1 201 ? 39.048  60.610  14.010  1.00 31.56  ? 201 ILE E CG1 1 
ATOM   15796 C CG2 . ILE E 1 201 ? 40.141  58.342  13.883  1.00 28.98  ? 201 ILE E CG2 1 
ATOM   15797 C CD1 . ILE E 1 201 ? 40.149  61.612  14.293  1.00 32.71  ? 201 ILE E CD1 1 
ATOM   15798 N N   . ALA E 1 202 ? 37.787  56.148  14.869  1.00 33.36  ? 202 ALA E N   1 
ATOM   15799 C CA  . ALA E 1 202 ? 37.803  54.793  15.389  1.00 33.30  ? 202 ALA E CA  1 
ATOM   15800 C C   . ALA E 1 202 ? 39.236  54.280  15.493  1.00 34.35  ? 202 ALA E C   1 
ATOM   15801 O O   . ALA E 1 202 ? 40.122  54.693  14.741  1.00 32.26  ? 202 ALA E O   1 
ATOM   15802 C CB  . ALA E 1 202 ? 36.967  53.896  14.483  1.00 31.03  ? 202 ALA E CB  1 
ATOM   15803 N N   . PRO E 1 203 ? 39.465  53.273  16.365  1.00 36.84  ? 203 PRO E N   1 
ATOM   15804 C CA  . PRO E 1 203 ? 40.751  52.578  16.412  1.00 36.95  ? 203 PRO E CA  1 
ATOM   15805 C C   . PRO E 1 203 ? 41.143  52.067  15.027  1.00 37.90  ? 203 PRO E C   1 
ATOM   15806 O O   . PRO E 1 203 ? 40.291  51.591  14.271  1.00 36.74  ? 203 PRO E O   1 
ATOM   15807 C CB  . PRO E 1 203 ? 40.523  51.404  17.387  1.00 36.08  ? 203 PRO E CB  1 
ATOM   15808 C CG  . PRO E 1 203 ? 39.265  51.765  18.161  1.00 36.25  ? 203 PRO E CG  1 
ATOM   15809 C CD  . PRO E 1 203 ? 38.462  52.688  17.270  1.00 34.31  ? 203 PRO E CD  1 
ATOM   15810 N N   . ASP E 1 204 ? 42.444  52.157  14.725  1.00 35.46  ? 204 ASP E N   1 
ATOM   15811 C CA  . ASP E 1 204 ? 43.036  51.468  13.597  1.00 31.70  ? 204 ASP E CA  1 
ATOM   15812 C C   . ASP E 1 204 ? 43.574  50.138  14.105  1.00 31.19  ? 204 ASP E C   1 
ATOM   15813 O O   . ASP E 1 204 ? 44.503  50.092  14.890  1.00 28.06  ? 204 ASP E O   1 
ATOM   15814 C CB  . ASP E 1 204 ? 44.100  52.339  12.949  1.00 33.78  ? 204 ASP E CB  1 
ATOM   15815 C CG  . ASP E 1 204 ? 44.817  51.760  11.741  1.00 34.17  ? 204 ASP E CG  1 
ATOM   15816 O OD1 . ASP E 1 204 ? 44.709  50.525  11.548  1.00 36.39  ? 204 ASP E OD1 1 
ATOM   15817 O OD2 . ASP E 1 204 ? 45.448  52.563  10.992  1.00 32.27  ? 204 ASP E OD2 1 
ATOM   15818 N N   . PRO E 1 205 ? 43.062  48.999  13.615  1.00 35.61  ? 205 PRO E N   1 
ATOM   15819 C CA  . PRO E 1 205 ? 43.569  47.695  14.054  1.00 35.36  ? 205 PRO E CA  1 
ATOM   15820 C C   . PRO E 1 205 ? 45.019  47.353  13.678  1.00 34.74  ? 205 PRO E C   1 
ATOM   15821 O O   . PRO E 1 205 ? 45.526  46.314  14.076  1.00 35.39  ? 205 PRO E O   1 
ATOM   15822 C CB  . PRO E 1 205 ? 42.542  46.720  13.405  1.00 33.93  ? 205 PRO E CB  1 
ATOM   15823 C CG  . PRO E 1 205 ? 42.088  47.440  12.152  1.00 33.93  ? 205 PRO E CG  1 
ATOM   15824 C CD  . PRO E 1 205 ? 42.050  48.913  12.546  1.00 35.64  ? 205 PRO E CD  1 
ATOM   15825 N N   . ASN E 1 206 ? 45.705  48.210  12.924  1.00 35.78  ? 206 ASN E N   1 
ATOM   15826 C CA  . ASN E 1 206 ? 47.096  47.947  12.569  1.00 42.52  ? 206 ASN E CA  1 
ATOM   15827 C C   . ASN E 1 206 ? 48.080  48.845  13.323  1.00 39.74  ? 206 ASN E C   1 
ATOM   15828 O O   . ASN E 1 206 ? 49.277  48.805  13.065  1.00 42.58  ? 206 ASN E O   1 
ATOM   15829 C CB  . ASN E 1 206 ? 47.324  48.119  11.068  1.00 49.27  ? 206 ASN E CB  1 
ATOM   15830 C CG  . ASN E 1 206 ? 46.549  47.086  10.278  1.00 57.49  ? 206 ASN E CG  1 
ATOM   15831 O OD1 . ASN E 1 206 ? 46.671  45.876  10.519  1.00 53.42  ? 206 ASN E OD1 1 
ATOM   15832 N ND2 . ASN E 1 206 ? 45.720  47.540  9.351   1.00 63.45  ? 206 ASN E ND2 1 
ATOM   15833 N N   . LEU E 1 207 ? 47.590  49.684  14.234  1.00 35.98  ? 207 LEU E N   1 
ATOM   15834 C CA  . LEU E 1 207 ? 48.478  50.546  14.991  1.00 33.66  ? 207 LEU E CA  1 
ATOM   15835 C C   . LEU E 1 207 ? 48.722  49.943  16.369  1.00 30.97  ? 207 LEU E C   1 
ATOM   15836 O O   . LEU E 1 207 ? 47.873  49.244  16.909  1.00 36.07  ? 207 LEU E O   1 
ATOM   15837 C CB  . LEU E 1 207 ? 47.883  51.950  15.053  1.00 32.18  ? 207 LEU E CB  1 
ATOM   15838 C CG  . LEU E 1 207 ? 47.894  52.739  13.732  1.00 30.72  ? 207 LEU E CG  1 
ATOM   15839 C CD1 . LEU E 1 207 ? 47.240  54.102  13.909  1.00 30.52  ? 207 LEU E CD1 1 
ATOM   15840 C CD2 . LEU E 1 207 ? 49.279  52.920  13.110  1.00 29.05  ? 207 LEU E CD2 1 
ATOM   15841 N N   . ASP E 1 208 ? 49.915  50.160  16.908  1.00 28.16  ? 208 ASP E N   1 
ATOM   15842 C CA  . ASP E 1 208 ? 50.178  49.884  18.314  1.00 27.55  ? 208 ASP E CA  1 
ATOM   15843 C C   . ASP E 1 208 ? 49.363  50.821  19.221  1.00 26.03  ? 208 ASP E C   1 
ATOM   15844 O O   . ASP E 1 208 ? 48.795  51.814  18.777  1.00 27.39  ? 208 ASP E O   1 
ATOM   15845 C CB  . ASP E 1 208 ? 51.666  49.996  18.598  1.00 28.22  ? 208 ASP E CB  1 
ATOM   15846 C CG  . ASP E 1 208 ? 52.299  51.282  18.092  1.00 28.15  ? 208 ASP E CG  1 
ATOM   15847 O OD1 . ASP E 1 208 ? 52.477  51.369  16.878  1.00 30.29  ? 208 ASP E OD1 1 
ATOM   15848 O OD2 . ASP E 1 208 ? 52.570  52.194  18.900  1.00 30.93  ? 208 ASP E OD2 1 
ATOM   15849 N N   . TRP E 1 209 ? 49.377  50.515  20.524  1.00 24.90  ? 209 TRP E N   1 
ATOM   15850 C CA  . TRP E 1 209 ? 48.572  51.160  21.551  1.00 23.72  ? 209 TRP E CA  1 
ATOM   15851 C C   . TRP E 1 209 ? 48.772  52.674  21.562  1.00 23.13  ? 209 TRP E C   1 
ATOM   15852 O O   . TRP E 1 209 ? 47.787  53.419  21.549  1.00 23.69  ? 209 TRP E O   1 
ATOM   15853 C CB  . TRP E 1 209 ? 48.924  50.505  22.895  1.00 27.16  ? 209 TRP E CB  1 
ATOM   15854 C CG  . TRP E 1 209 ? 48.092  50.884  24.091  1.00 27.88  ? 209 TRP E CG  1 
ATOM   15855 C CD1 . TRP E 1 209 ? 46.821  50.493  24.400  1.00 27.42  ? 209 TRP E CD1 1 
ATOM   15856 C CD2 . TRP E 1 209 ? 48.534  51.708  25.182  1.00 29.17  ? 209 TRP E CD2 1 
ATOM   15857 N NE1 . TRP E 1 209 ? 46.423  51.061  25.576  1.00 27.42  ? 209 TRP E NE1 1 
ATOM   15858 C CE2 . TRP E 1 209 ? 47.459  51.792  26.091  1.00 28.78  ? 209 TRP E CE2 1 
ATOM   15859 C CE3 . TRP E 1 209 ? 49.723  52.390  25.461  1.00 28.12  ? 209 TRP E CE3 1 
ATOM   15860 C CZ2 . TRP E 1 209 ? 47.546  52.529  27.269  1.00 30.88  ? 209 TRP E CZ2 1 
ATOM   15861 C CZ3 . TRP E 1 209 ? 49.804  53.131  26.617  1.00 30.83  ? 209 TRP E CZ3 1 
ATOM   15862 C CH2 . TRP E 1 209 ? 48.730  53.191  27.515  1.00 33.03  ? 209 TRP E CH2 1 
ATOM   15863 N N   . SER E 1 210 ? 50.033  53.126  21.535  1.00 24.55  ? 210 SER E N   1 
ATOM   15864 C CA  . SER E 1 210 ? 50.362  54.545  21.664  1.00 26.65  ? 210 SER E CA  1 
ATOM   15865 C C   . SER E 1 210 ? 49.877  55.318  20.441  1.00 25.46  ? 210 SER E C   1 
ATOM   15866 O O   . SER E 1 210 ? 49.253  56.377  20.544  1.00 23.04  ? 210 SER E O   1 
ATOM   15867 C CB  . SER E 1 210 ? 51.870  54.784  21.834  1.00 30.83  ? 210 SER E CB  1 
ATOM   15868 O OG  . SER E 1 210 ? 52.466  53.900  22.765  1.00 32.55  ? 210 SER E OG  1 
ATOM   15869 N N   . ALA E 1 211 ? 50.246  54.777  19.277  1.00 26.87  ? 211 ALA E N   1 
ATOM   15870 C CA  . ALA E 1 211 ? 49.910  55.349  17.986  1.00 27.95  ? 211 ALA E CA  1 
ATOM   15871 C C   . ALA E 1 211 ? 48.395  55.500  17.836  1.00 26.31  ? 211 ALA E C   1 
ATOM   15872 O O   . ALA E 1 211 ? 47.918  56.520  17.333  1.00 26.73  ? 211 ALA E O   1 
ATOM   15873 C CB  . ALA E 1 211 ? 50.482  54.436  16.922  1.00 29.88  ? 211 ALA E CB  1 
ATOM   15874 N N   . ASN E 1 212 ? 47.653  54.473  18.276  1.00 23.56  ? 212 ASN E N   1 
ATOM   15875 C CA  . ASN E 1 212 ? 46.205  54.497  18.178  1.00 25.30  ? 212 ASN E CA  1 
ATOM   15876 C C   . ASN E 1 212 ? 45.643  55.669  18.966  1.00 23.14  ? 212 ASN E C   1 
ATOM   15877 O O   . ASN E 1 212 ? 44.691  56.268  18.512  1.00 21.03  ? 212 ASN E O   1 
ATOM   15878 C CB  . ASN E 1 212 ? 45.523  53.212  18.638  1.00 28.07  ? 212 ASN E CB  1 
ATOM   15879 C CG  . ASN E 1 212 ? 44.914  52.435  17.499  1.00 27.19  ? 212 ASN E CG  1 
ATOM   15880 O OD1 . ASN E 1 212 ? 44.386  53.033  16.562  1.00 32.41  ? 212 ASN E OD1 1 
ATOM   15881 N ND2 . ASN E 1 212 ? 45.001  51.121  17.546  1.00 26.31  ? 212 ASN E ND2 1 
ATOM   15882 N N   . LEU E 1 213 ? 46.244  56.003  20.110  1.00 21.57  ? 213 LEU E N   1 
ATOM   15883 C CA  . LEU E 1 213 ? 45.778  57.154  20.863  1.00 23.41  ? 213 LEU E CA  1 
ATOM   15884 C C   . LEU E 1 213 ? 45.934  58.402  19.990  1.00 22.91  ? 213 LEU E C   1 
ATOM   15885 O O   . LEU E 1 213 ? 44.994  59.173  19.802  1.00 19.65  ? 213 LEU E O   1 
ATOM   15886 C CB  . LEU E 1 213 ? 46.507  57.291  22.205  1.00 24.30  ? 213 LEU E CB  1 
ATOM   15887 C CG  . LEU E 1 213 ? 46.273  58.581  23.001  1.00 24.22  ? 213 LEU E CG  1 
ATOM   15888 C CD1 . LEU E 1 213 ? 44.809  58.865  23.285  1.00 23.43  ? 213 LEU E CD1 1 
ATOM   15889 C CD2 . LEU E 1 213 ? 47.040  58.476  24.304  1.00 26.11  ? 213 LEU E CD2 1 
ATOM   15890 N N   . ALA E 1 214 ? 47.130  58.590  19.448  1.00 22.60  ? 214 ALA E N   1 
ATOM   15891 C CA  . ALA E 1 214 ? 47.347  59.697  18.536  1.00 23.58  ? 214 ALA E CA  1 
ATOM   15892 C C   . ALA E 1 214 ? 46.362  59.663  17.370  1.00 23.74  ? 214 ALA E C   1 
ATOM   15893 O O   . ALA E 1 214 ? 45.850  60.708  16.964  1.00 20.80  ? 214 ALA E O   1 
ATOM   15894 C CB  . ALA E 1 214 ? 48.745  59.632  18.022  1.00 26.34  ? 214 ALA E CB  1 
ATOM   15895 N N   . HIS E 1 215 ? 46.132  58.465  16.813  1.00 24.20  ? 215 HIS E N   1 
ATOM   15896 C CA  . HIS E 1 215 ? 45.266  58.343  15.660  1.00 24.98  ? 215 HIS E CA  1 
ATOM   15897 C C   . HIS E 1 215 ? 43.863  58.812  16.030  1.00 25.70  ? 215 HIS E C   1 
ATOM   15898 O O   . HIS E 1 215 ? 43.269  59.648  15.351  1.00 26.50  ? 215 HIS E O   1 
ATOM   15899 C CB  . HIS E 1 215 ? 45.243  56.905  15.143  1.00 27.86  ? 215 HIS E CB  1 
ATOM   15900 C CG  . HIS E 1 215 ? 44.263  56.666  14.028  1.00 29.48  ? 215 HIS E CG  1 
ATOM   15901 N ND1 . HIS E 1 215 ? 44.331  57.326  12.815  1.00 28.30  ? 215 HIS E ND1 1 
ATOM   15902 C CD2 . HIS E 1 215 ? 43.166  55.864  13.967  1.00 29.75  ? 215 HIS E CD2 1 
ATOM   15903 C CE1 . HIS E 1 215 ? 43.324  56.900  12.042  1.00 34.26  ? 215 HIS E CE1 1 
ATOM   15904 N NE2 . HIS E 1 215 ? 42.599  56.011  12.719  1.00 29.91  ? 215 HIS E NE2 1 
ATOM   15905 N N   . MET E 1 216 ? 43.377  58.313  17.162  1.00 22.91  ? 216 MET E N   1 
ATOM   15906 C CA  . MET E 1 216 ? 42.028  58.604  17.598  1.00 22.65  ? 216 MET E CA  1 
ATOM   15907 C C   . MET E 1 216 ? 41.889  60.067  18.040  1.00 24.31  ? 216 MET E C   1 
ATOM   15908 O O   . MET E 1 216 ? 40.779  60.594  18.039  1.00 27.22  ? 216 MET E O   1 
ATOM   15909 C CB  . MET E 1 216 ? 41.607  57.588  18.671  1.00 21.83  ? 216 MET E CB  1 
ATOM   15910 C CG  . MET E 1 216 ? 41.409  56.178  18.121  1.00 22.13  ? 216 MET E CG  1 
ATOM   15911 S SD  . MET E 1 216 ? 40.720  55.060  19.349  1.00 26.09  ? 216 MET E SD  1 
ATOM   15912 C CE  . MET E 1 216 ? 41.919  55.281  20.666  1.00 24.96  ? 216 MET E CE  1 
ATOM   15913 N N   . MET E 1 217 ? 42.995  60.731  18.407  1.00 22.66  ? 217 MET E N   1 
ATOM   15914 C CA  . MET E 1 217 ? 42.959  62.151  18.698  1.00 24.10  ? 217 MET E CA  1 
ATOM   15915 C C   . MET E 1 217 ? 43.119  62.983  17.409  1.00 26.59  ? 217 MET E C   1 
ATOM   15916 O O   . MET E 1 217 ? 42.894  64.206  17.414  1.00 25.69  ? 217 MET E O   1 
ATOM   15917 C CB  . MET E 1 217 ? 44.060  62.543  19.692  1.00 26.08  ? 217 MET E CB  1 
ATOM   15918 C CG  . MET E 1 217 ? 43.957  61.917  21.074  1.00 28.23  ? 217 MET E CG  1 
ATOM   15919 S SD  . MET E 1 217 ? 45.441  62.247  22.058  1.00 29.78  ? 217 MET E SD  1 
ATOM   15920 C CE  . MET E 1 217 ? 45.523  64.046  22.154  1.00 27.46  ? 217 MET E CE  1 
ATOM   15921 N N   . GLY E 1 218 ? 43.507  62.338  16.298  1.00 26.07  ? 218 GLY E N   1 
ATOM   15922 C CA  . GLY E 1 218 ? 43.481  62.986  14.993  1.00 25.99  ? 218 GLY E CA  1 
ATOM   15923 C C   . GLY E 1 218 ? 44.862  63.390  14.488  1.00 27.70  ? 218 GLY E C   1 
ATOM   15924 O O   . GLY E 1 218 ? 44.965  64.356  13.739  1.00 29.65  ? 218 GLY E O   1 
ATOM   15925 N N   . PHE E 1 219 ? 45.900  62.657  14.921  1.00 30.54  ? 219 PHE E N   1 
ATOM   15926 C CA  . PHE E 1 219 ? 47.293  62.905  14.562  1.00 30.50  ? 219 PHE E CA  1 
ATOM   15927 C C   . PHE E 1 219 ? 47.903  61.642  13.955  1.00 29.06  ? 219 PHE E C   1 
ATOM   15928 O O   . PHE E 1 219 ? 47.978  60.629  14.633  1.00 29.24  ? 219 PHE E O   1 
ATOM   15929 C CB  . PHE E 1 219 ? 48.068  63.335  15.812  1.00 29.07  ? 219 PHE E CB  1 
ATOM   15930 C CG  . PHE E 1 219 ? 47.538  64.588  16.494  1.00 28.73  ? 219 PHE E CG  1 
ATOM   15931 C CD1 . PHE E 1 219 ? 47.928  65.854  16.069  1.00 30.41  ? 219 PHE E CD1 1 
ATOM   15932 C CD2 . PHE E 1 219 ? 46.656  64.500  17.558  1.00 28.82  ? 219 PHE E CD2 1 
ATOM   15933 C CE1 . PHE E 1 219 ? 47.432  66.999  16.674  1.00 28.93  ? 219 PHE E CE1 1 
ATOM   15934 C CE2 . PHE E 1 219 ? 46.170  65.643  18.165  1.00 28.31  ? 219 PHE E CE2 1 
ATOM   15935 C CZ  . PHE E 1 219 ? 46.567  66.886  17.737  1.00 27.98  ? 219 PHE E CZ  1 
ATOM   15936 N N   . ASP E 1 220 ? 48.348  61.685  12.688  1.00 32.13  ? 220 ASP E N   1 
ATOM   15937 C CA  . ASP E 1 220 ? 48.853  60.464  12.070  1.00 34.35  ? 220 ASP E CA  1 
ATOM   15938 C C   . ASP E 1 220 ? 50.291  60.559  11.560  1.00 32.80  ? 220 ASP E C   1 
ATOM   15939 O O   . ASP E 1 220 ? 50.770  59.575  10.995  1.00 34.75  ? 220 ASP E O   1 
ATOM   15940 C CB  . ASP E 1 220 ? 47.886  59.917  11.035  1.00 34.71  ? 220 ASP E CB  1 
ATOM   15941 C CG  . ASP E 1 220 ? 46.547  59.466  11.610  1.00 35.64  ? 220 ASP E CG  1 
ATOM   15942 O OD1 . ASP E 1 220 ? 46.499  58.384  12.257  1.00 35.49  ? 220 ASP E OD1 1 
ATOM   15943 O OD2 . ASP E 1 220 ? 45.572  60.226  11.449  1.00 31.27  ? 220 ASP E OD2 1 
ATOM   15944 N N   . ASP E 1 221 ? 50.999  61.677  11.798  1.00 30.77  ? 221 ASP E N   1 
ATOM   15945 C CA  . ASP E 1 221 ? 52.409  61.761  11.455  1.00 31.21  ? 221 ASP E CA  1 
ATOM   15946 C C   . ASP E 1 221 ? 53.239  60.752  12.240  1.00 29.86  ? 221 ASP E C   1 
ATOM   15947 O O   . ASP E 1 221 ? 53.122  60.640  13.458  1.00 31.94  ? 221 ASP E O   1 
ATOM   15948 C CB  . ASP E 1 221 ? 52.989  63.133  11.732  1.00 36.45  ? 221 ASP E CB  1 
ATOM   15949 C CG  . ASP E 1 221 ? 52.591  64.218  10.747  1.00 45.06  ? 221 ASP E CG  1 
ATOM   15950 O OD1 . ASP E 1 221 ? 51.897  63.881  9.770   1.00 46.05  ? 221 ASP E OD1 1 
ATOM   15951 O OD2 . ASP E 1 221 ? 52.983  65.390  10.970  1.00 56.19  ? 221 ASP E OD2 1 
ATOM   15952 N N   . PHE E 1 222 ? 54.141  60.063  11.539  1.00 34.44  ? 222 PHE E N   1 
ATOM   15953 C CA  . PHE E 1 222 ? 55.024  59.068  12.144  1.00 34.68  ? 222 PHE E CA  1 
ATOM   15954 C C   . PHE E 1 222 ? 55.803  59.615  13.355  1.00 33.45  ? 222 PHE E C   1 
ATOM   15955 O O   . PHE E 1 222 ? 56.051  58.893  14.321  1.00 28.27  ? 222 PHE E O   1 
ATOM   15956 C CB  . PHE E 1 222 ? 55.940  58.558  11.031  1.00 35.55  ? 222 PHE E CB  1 
ATOM   15957 C CG  . PHE E 1 222 ? 57.123  57.751  11.543  1.00 36.41  ? 222 PHE E CG  1 
ATOM   15958 C CD1 . PHE E 1 222 ? 56.959  56.397  11.850  1.00 35.75  ? 222 PHE E CD1 1 
ATOM   15959 C CD2 . PHE E 1 222 ? 58.371  58.352  11.712  1.00 35.02  ? 222 PHE E CD2 1 
ATOM   15960 C CE1 . PHE E 1 222 ? 58.015  55.656  12.334  1.00 34.86  ? 222 PHE E CE1 1 
ATOM   15961 C CE2 . PHE E 1 222 ? 59.437  57.611  12.196  1.00 38.17  ? 222 PHE E CE2 1 
ATOM   15962 C CZ  . PHE E 1 222 ? 59.258  56.267  12.498  1.00 39.94  ? 222 PHE E CZ  1 
ATOM   15963 N N   . GLU E 1 223 ? 56.220  60.886  13.293  1.00 34.80  ? 223 GLU E N   1 
ATOM   15964 C CA  . GLU E 1 223 ? 56.927  61.525  14.393  1.00 35.16  ? 223 GLU E CA  1 
ATOM   15965 C C   . GLU E 1 223 ? 56.035  61.582  15.637  1.00 32.75  ? 223 GLU E C   1 
ATOM   15966 O O   . GLU E 1 223 ? 56.505  61.384  16.762  1.00 28.16  ? 223 GLU E O   1 
ATOM   15967 C CB  . GLU E 1 223 ? 57.357  62.949  14.031  1.00 40.81  ? 223 GLU E CB  1 
ATOM   15968 C CG  . GLU E 1 223 ? 58.638  63.066  13.204  1.00 46.28  ? 223 GLU E CG  1 
ATOM   15969 C CD  . GLU E 1 223 ? 59.024  64.489  12.785  1.00 52.26  ? 223 GLU E CD  1 
ATOM   15970 O OE1 . GLU E 1 223 ? 59.455  64.618  11.613  1.00 59.15  ? 223 GLU E OE1 1 
ATOM   15971 O OE2 . GLU E 1 223 ? 58.916  65.468  13.582  1.00 44.99  ? 223 GLU E OE2 1 
ATOM   15972 N N   . VAL E 1 224 ? 54.744  61.878  15.427  1.00 30.99  ? 224 VAL E N   1 
ATOM   15973 C CA  . VAL E 1 224 ? 53.806  62.014  16.524  1.00 29.59  ? 224 VAL E CA  1 
ATOM   15974 C C   . VAL E 1 224 ? 53.614  60.638  17.151  1.00 26.38  ? 224 VAL E C   1 
ATOM   15975 O O   . VAL E 1 224 ? 53.610  60.515  18.378  1.00 20.47  ? 224 VAL E O   1 
ATOM   15976 C CB  . VAL E 1 224 ? 52.463  62.646  16.114  1.00 30.56  ? 224 VAL E CB  1 
ATOM   15977 C CG1 . VAL E 1 224 ? 51.497  62.653  17.277  1.00 30.61  ? 224 VAL E CG1 1 
ATOM   15978 C CG2 . VAL E 1 224 ? 52.664  64.073  15.651  1.00 34.39  ? 224 VAL E CG2 1 
ATOM   15979 N N   . TYR E 1 225 ? 53.418  59.614  16.299  1.00 24.47  ? 225 TYR E N   1 
ATOM   15980 C CA  . TYR E 1 225 ? 53.346  58.269  16.831  1.00 24.10  ? 225 TYR E CA  1 
ATOM   15981 C C   . TYR E 1 225 ? 54.598  58.025  17.683  1.00 24.92  ? 225 TYR E C   1 
ATOM   15982 O O   . TYR E 1 225 ? 54.535  57.472  18.775  1.00 25.22  ? 225 TYR E O   1 
ATOM   15983 C CB  . TYR E 1 225 ? 53.217  57.220  15.736  1.00 23.45  ? 225 TYR E CB  1 
ATOM   15984 C CG  . TYR E 1 225 ? 51.955  57.194  14.890  1.00 26.24  ? 225 TYR E CG  1 
ATOM   15985 C CD1 . TYR E 1 225 ? 50.785  57.838  15.285  1.00 27.36  ? 225 TYR E CD1 1 
ATOM   15986 C CD2 . TYR E 1 225 ? 51.910  56.444  13.700  1.00 27.53  ? 225 TYR E CD2 1 
ATOM   15987 C CE1 . TYR E 1 225 ? 49.636  57.774  14.504  1.00 26.71  ? 225 TYR E CE1 1 
ATOM   15988 C CE2 . TYR E 1 225 ? 50.750  56.334  12.942  1.00 25.76  ? 225 TYR E CE2 1 
ATOM   15989 C CZ  . TYR E 1 225 ? 49.605  57.009  13.346  1.00 26.11  ? 225 TYR E CZ  1 
ATOM   15990 O OH  . TYR E 1 225 ? 48.433  56.911  12.637  1.00 25.77  ? 225 TYR E OH  1 
ATOM   15991 N N   . GLU E 1 226 ? 55.759  58.412  17.159  1.00 23.73  ? 226 GLU E N   1 
ATOM   15992 C CA  . GLU E 1 226 ? 57.009  58.140  17.842  1.00 24.10  ? 226 GLU E CA  1 
ATOM   15993 C C   . GLU E 1 226 ? 57.065  58.914  19.150  1.00 24.70  ? 226 GLU E C   1 
ATOM   15994 O O   . GLU E 1 226 ? 57.552  58.376  20.134  1.00 27.05  ? 226 GLU E O   1 
ATOM   15995 C CB  . GLU E 1 226 ? 58.206  58.443  16.942  1.00 23.80  ? 226 GLU E CB  1 
ATOM   15996 C CG  . GLU E 1 226 ? 58.355  57.390  15.845  1.00 22.91  ? 226 GLU E CG  1 
ATOM   15997 C CD  . GLU E 1 226 ? 59.048  56.172  16.386  1.00 23.11  ? 226 GLU E CD  1 
ATOM   15998 O OE1 . GLU E 1 226 ? 58.393  55.167  16.713  1.00 25.71  ? 226 GLU E OE1 1 
ATOM   15999 O OE2 . GLU E 1 226 ? 60.291  56.247  16.464  1.00 23.08  ? 226 GLU E OE2 1 
ATOM   16000 N N   . LEU E 1 227 ? 56.561  60.155  19.165  1.00 26.40  ? 227 LEU E N   1 
ATOM   16001 C CA  . LEU E 1 227 ? 56.489  60.932  20.394  1.00 26.40  ? 227 LEU E CA  1 
ATOM   16002 C C   . LEU E 1 227 ? 55.602  60.217  21.416  1.00 27.17  ? 227 LEU E C   1 
ATOM   16003 O O   . LEU E 1 227 ? 55.971  60.088  22.583  1.00 24.21  ? 227 LEU E O   1 
ATOM   16004 C CB  . LEU E 1 227 ? 55.978  62.347  20.139  1.00 25.41  ? 227 LEU E CB  1 
ATOM   16005 C CG  . LEU E 1 227 ? 55.727  63.177  21.398  1.00 26.33  ? 227 LEU E CG  1 
ATOM   16006 C CD1 . LEU E 1 227 ? 56.976  63.181  22.240  1.00 26.63  ? 227 LEU E CD1 1 
ATOM   16007 C CD2 . LEU E 1 227 ? 55.303  64.590  21.043  1.00 28.78  ? 227 LEU E CD2 1 
ATOM   16008 N N   . PHE E 1 228 ? 54.438  59.750  20.955  1.00 24.98  ? 228 PHE E N   1 
ATOM   16009 C CA  . PHE E 1 228 ? 53.472  59.146  21.850  1.00 25.55  ? 228 PHE E CA  1 
ATOM   16010 C C   . PHE E 1 228 ? 54.082  57.895  22.454  1.00 28.54  ? 228 PHE E C   1 
ATOM   16011 O O   . PHE E 1 228 ? 53.923  57.684  23.654  1.00 32.77  ? 228 PHE E O   1 
ATOM   16012 C CB  . PHE E 1 228 ? 52.113  58.872  21.205  1.00 23.72  ? 228 PHE E CB  1 
ATOM   16013 C CG  . PHE E 1 228 ? 51.231  60.108  21.235  1.00 24.36  ? 228 PHE E CG  1 
ATOM   16014 C CD1 . PHE E 1 228 ? 51.750  61.377  20.983  1.00 27.10  ? 228 PHE E CD1 1 
ATOM   16015 C CD2 . PHE E 1 228 ? 49.889  60.017  21.581  1.00 25.87  ? 228 PHE E CD2 1 
ATOM   16016 C CE1 . PHE E 1 228 ? 50.942  62.514  21.031  1.00 27.07  ? 228 PHE E CE1 1 
ATOM   16017 C CE2 . PHE E 1 228 ? 49.090  61.153  21.657  1.00 24.83  ? 228 PHE E CE2 1 
ATOM   16018 C CZ  . PHE E 1 228 ? 49.610  62.392  21.377  1.00 25.84  ? 228 PHE E CZ  1 
ATOM   16019 N N   . ARG E 1 229 ? 54.797  57.099  21.655  1.00 28.27  ? 229 ARG E N   1 
ATOM   16020 C CA  . ARG E 1 229 ? 55.376  55.870  22.175  1.00 31.82  ? 229 ARG E CA  1 
ATOM   16021 C C   . ARG E 1 229 ? 56.406  56.201  23.260  1.00 29.90  ? 229 ARG E C   1 
ATOM   16022 O O   . ARG E 1 229 ? 56.411  55.602  24.332  1.00 26.78  ? 229 ARG E O   1 
ATOM   16023 C CB  . ARG E 1 229 ? 56.013  55.039  21.057  1.00 34.50  ? 229 ARG E CB  1 
ATOM   16024 C CG  . ARG E 1 229 ? 55.016  54.529  20.030  1.00 35.03  ? 229 ARG E CG  1 
ATOM   16025 C CD  . ARG E 1 229 ? 55.685  54.172  18.736  1.00 34.79  ? 229 ARG E CD  1 
ATOM   16026 N NE  . ARG E 1 229 ? 54.772  53.591  17.748  1.00 35.91  ? 229 ARG E NE  1 
ATOM   16027 C CZ  . ARG E 1 229 ? 54.762  53.920  16.464  1.00 37.40  ? 229 ARG E CZ  1 
ATOM   16028 N NH1 . ARG E 1 229 ? 55.674  54.739  15.962  1.00 35.91  ? 229 ARG E NH1 1 
ATOM   16029 N NH2 . ARG E 1 229 ? 53.834  53.425  15.673  1.00 36.22  ? 229 ARG E NH2 1 
ATOM   16030 N N   . LEU E 1 230 ? 57.272  57.174  22.984  1.00 28.34  ? 230 LEU E N   1 
ATOM   16031 C CA  . LEU E 1 230 ? 58.289  57.542  23.947  1.00 29.84  ? 230 LEU E CA  1 
ATOM   16032 C C   . LEU E 1 230 ? 57.644  58.039  25.247  1.00 29.96  ? 230 LEU E C   1 
ATOM   16033 O O   . LEU E 1 230 ? 58.075  57.673  26.343  1.00 31.40  ? 230 LEU E O   1 
ATOM   16034 C CB  . LEU E 1 230 ? 59.215  58.612  23.371  1.00 29.25  ? 230 LEU E CB  1 
ATOM   16035 C CG  . LEU E 1 230 ? 60.308  59.103  24.332  1.00 28.65  ? 230 LEU E CG  1 
ATOM   16036 C CD1 . LEU E 1 230 ? 61.301  57.974  24.691  1.00 26.66  ? 230 LEU E CD1 1 
ATOM   16037 C CD2 . LEU E 1 230 ? 60.987  60.319  23.755  1.00 26.57  ? 230 LEU E CD2 1 
ATOM   16038 N N   . TYR E 1 231 ? 56.647  58.913  25.099  1.00 27.65  ? 231 TYR E N   1 
ATOM   16039 C CA  . TYR E 1 231 ? 56.017  59.604  26.206  1.00 28.08  ? 231 TYR E CA  1 
ATOM   16040 C C   . TYR E 1 231 ? 55.424  58.559  27.131  1.00 25.78  ? 231 TYR E C   1 
ATOM   16041 O O   . TYR E 1 231 ? 55.608  58.630  28.354  1.00 26.44  ? 231 TYR E O   1 
ATOM   16042 C CB  . TYR E 1 231 ? 54.955  60.597  25.697  1.00 31.65  ? 231 TYR E CB  1 
ATOM   16043 C CG  . TYR E 1 231 ? 54.156  61.332  26.766  1.00 33.46  ? 231 TYR E CG  1 
ATOM   16044 C CD1 . TYR E 1 231 ? 53.143  60.679  27.461  1.00 34.29  ? 231 TYR E CD1 1 
ATOM   16045 C CD2 . TYR E 1 231 ? 54.393  62.667  27.068  1.00 35.71  ? 231 TYR E CD2 1 
ATOM   16046 C CE1 . TYR E 1 231 ? 52.396  61.326  28.430  1.00 33.74  ? 231 TYR E CE1 1 
ATOM   16047 C CE2 . TYR E 1 231 ? 53.636  63.331  28.027  1.00 36.60  ? 231 TYR E CE2 1 
ATOM   16048 C CZ  . TYR E 1 231 ? 52.639  62.654  28.712  1.00 35.14  ? 231 TYR E CZ  1 
ATOM   16049 O OH  . TYR E 1 231 ? 51.908  63.225  29.717  1.00 40.40  ? 231 TYR E OH  1 
ATOM   16050 N N   . MET E 1 232 ? 54.700  57.624  26.517  1.00 23.92  ? 232 MET E N   1 
ATOM   16051 C CA  . MET E 1 232 ? 54.017  56.586  27.257  1.00 23.50  ? 232 MET E CA  1 
ATOM   16052 C C   . MET E 1 232 ? 55.046  55.750  27.998  1.00 23.25  ? 232 MET E C   1 
ATOM   16053 O O   . MET E 1 232 ? 54.752  55.200  29.045  1.00 20.77  ? 232 MET E O   1 
ATOM   16054 C CB  . MET E 1 232 ? 53.224  55.650  26.337  1.00 24.05  ? 232 MET E CB  1 
ATOM   16055 C CG  . MET E 1 232 ? 51.979  56.275  25.783  1.00 25.36  ? 232 MET E CG  1 
ATOM   16056 S SD  . MET E 1 232 ? 50.947  56.927  27.096  1.00 27.59  ? 232 MET E SD  1 
ATOM   16057 C CE  . MET E 1 232 ? 50.240  58.404  26.373  1.00 30.44  ? 232 MET E CE  1 
ATOM   16058 N N   . PHE E 1 233 ? 56.238  55.616  27.411  1.00 25.84  ? 233 PHE E N   1 
ATOM   16059 C CA  . PHE E 1 233 ? 57.295  54.811  28.003  1.00 25.46  ? 233 PHE E CA  1 
ATOM   16060 C C   . PHE E 1 233 ? 57.883  55.534  29.219  1.00 24.85  ? 233 PHE E C   1 
ATOM   16061 O O   . PHE E 1 233 ? 58.096  54.922  30.269  1.00 22.00  ? 233 PHE E O   1 
ATOM   16062 C CB  . PHE E 1 233 ? 58.297  54.526  26.878  1.00 24.46  ? 233 PHE E CB  1 
ATOM   16063 C CG  . PHE E 1 233 ? 59.651  54.046  27.367  1.00 24.34  ? 233 PHE E CG  1 
ATOM   16064 C CD1 . PHE E 1 233 ? 59.909  52.697  27.521  1.00 23.67  ? 233 PHE E CD1 1 
ATOM   16065 C CD2 . PHE E 1 233 ? 60.668  54.954  27.625  1.00 24.42  ? 233 PHE E CD2 1 
ATOM   16066 C CE1 . PHE E 1 233 ? 61.140  52.269  27.961  1.00 26.28  ? 233 PHE E CE1 1 
ATOM   16067 C CE2 . PHE E 1 233 ? 61.902  54.516  28.048  1.00 26.45  ? 233 PHE E CE2 1 
ATOM   16068 C CZ  . PHE E 1 233 ? 62.124  53.177  28.249  1.00 27.67  ? 233 PHE E CZ  1 
ATOM   16069 N N   . LEU E 1 234 ? 58.178  56.835  29.064  1.00 24.36  ? 234 LEU E N   1 
ATOM   16070 C CA  . LEU E 1 234 ? 58.951  57.541  30.084  1.00 27.64  ? 234 LEU E CA  1 
ATOM   16071 C C   . LEU E 1 234 ? 58.111  57.703  31.341  1.00 27.36  ? 234 LEU E C   1 
ATOM   16072 O O   . LEU E 1 234 ? 58.662  57.760  32.429  1.00 31.66  ? 234 LEU E O   1 
ATOM   16073 C CB  . LEU E 1 234 ? 59.452  58.920  29.649  1.00 26.34  ? 234 LEU E CB  1 
ATOM   16074 C CG  . LEU E 1 234 ? 60.413  58.929  28.463  1.00 26.12  ? 234 LEU E CG  1 
ATOM   16075 C CD1 . LEU E 1 234 ? 60.663  60.317  27.901  1.00 26.22  ? 234 LEU E CD1 1 
ATOM   16076 C CD2 . LEU E 1 234 ? 61.697  58.288  28.896  1.00 27.18  ? 234 LEU E CD2 1 
ATOM   16077 N N   . HIS E 1 235 ? 56.794  57.857  31.142  1.00 28.90  ? 235 HIS E N   1 
ATOM   16078 C CA  . HIS E 1 235 ? 55.883  58.315  32.175  1.00 26.28  ? 235 HIS E CA  1 
ATOM   16079 C C   . HIS E 1 235 ? 55.224  57.110  32.843  1.00 24.92  ? 235 HIS E C   1 
ATOM   16080 O O   . HIS E 1 235 ? 54.421  57.290  33.729  1.00 21.03  ? 235 HIS E O   1 
ATOM   16081 C CB  . HIS E 1 235 ? 54.858  59.288  31.583  1.00 23.97  ? 235 HIS E CB  1 
ATOM   16082 C CG  . HIS E 1 235 ? 55.393  60.634  31.260  1.00 23.09  ? 235 HIS E CG  1 
ATOM   16083 N ND1 . HIS E 1 235 ? 55.887  60.958  30.019  1.00 26.51  ? 235 HIS E ND1 1 
ATOM   16084 C CD2 . HIS E 1 235 ? 55.442  61.779  31.978  1.00 25.65  ? 235 HIS E CD2 1 
ATOM   16085 C CE1 . HIS E 1 235 ? 56.257  62.258  30.032  1.00 29.61  ? 235 HIS E CE1 1 
ATOM   16086 N NE2 . HIS E 1 235 ? 55.991  62.780  31.218  1.00 24.03  ? 235 HIS E NE2 1 
ATOM   16087 N N   . SER E 1 236 ? 55.585  55.888  32.438  1.00 25.28  ? 236 SER E N   1 
ATOM   16088 C CA  . SER E 1 236 ? 54.804  54.720  32.805  1.00 25.88  ? 236 SER E CA  1 
ATOM   16089 C C   . SER E 1 236 ? 54.763  54.512  34.324  1.00 26.81  ? 236 SER E C   1 
ATOM   16090 O O   . SER E 1 236 ? 53.751  54.047  34.838  1.00 24.49  ? 236 SER E O   1 
ATOM   16091 C CB  . SER E 1 236 ? 55.343  53.497  32.122  1.00 24.67  ? 236 SER E CB  1 
ATOM   16092 O OG  . SER E 1 236 ? 56.706  53.308  32.475  1.00 25.39  ? 236 SER E OG  1 
ATOM   16093 N N   . ASP E 1 237 ? 55.890  54.752  35.018  1.00 30.43  ? 237 ASP E N   1 
ATOM   16094 C CA  . ASP E 1 237 ? 56.069  54.345  36.414  1.00 30.36  ? 237 ASP E CA  1 
ATOM   16095 C C   . ASP E 1 237 ? 57.131  55.215  37.091  1.00 29.04  ? 237 ASP E C   1 
ATOM   16096 O O   . ASP E 1 237 ? 58.068  55.689  36.445  1.00 30.94  ? 237 ASP E O   1 
ATOM   16097 C CB  . ASP E 1 237 ? 56.378  52.860  36.553  1.00 29.73  ? 237 ASP E CB  1 
ATOM   16098 C CG  . ASP E 1 237 ? 55.986  52.204  37.878  1.00 32.33  ? 237 ASP E CG  1 
ATOM   16099 O OD1 . ASP E 1 237 ? 54.796  52.345  38.256  1.00 30.88  ? 237 ASP E OD1 1 
ATOM   16100 O OD2 . ASP E 1 237 ? 56.862  51.505  38.501  1.00 31.17  ? 237 ASP E OD2 1 
ATOM   16101 N N   . HIS E 1 238 ? 56.927  55.448  38.394  1.00 27.61  ? 238 HIS E N   1 
ATOM   16102 C CA  . HIS E 1 238 ? 57.870  56.177  39.223  1.00 25.65  ? 238 HIS E CA  1 
ATOM   16103 C C   . HIS E 1 238 ? 57.652  55.789  40.688  1.00 23.90  ? 238 HIS E C   1 
ATOM   16104 O O   . HIS E 1 238 ? 57.212  56.587  41.504  1.00 24.10  ? 238 HIS E O   1 
ATOM   16105 C CB  . HIS E 1 238 ? 57.801  57.667  38.885  1.00 25.08  ? 238 HIS E CB  1 
ATOM   16106 C CG  . HIS E 1 238 ? 59.032  58.435  39.294  1.00 32.09  ? 238 HIS E CG  1 
ATOM   16107 N ND1 . HIS E 1 238 ? 59.120  59.216  40.438  1.00 33.28  ? 238 HIS E ND1 1 
ATOM   16108 C CD2 . HIS E 1 238 ? 60.228  58.551  38.689  1.00 31.02  ? 238 HIS E CD2 1 
ATOM   16109 C CE1 . HIS E 1 238 ? 60.300  59.815  40.488  1.00 30.47  ? 238 HIS E CE1 1 
ATOM   16110 N NE2 . HIS E 1 238 ? 60.997  59.418  39.441  1.00 32.18  ? 238 HIS E NE2 1 
ATOM   16111 N N   . GLU E 1 239 ? 57.950  54.533  41.027  1.00 27.44  ? 239 GLU E N   1 
ATOM   16112 C CA  . GLU E 1 239 ? 57.803  54.025  42.397  1.00 27.86  ? 239 GLU E CA  1 
ATOM   16113 C C   . GLU E 1 239 ? 56.310  53.966  42.742  1.00 27.36  ? 239 GLU E C   1 
ATOM   16114 O O   . GLU E 1 239 ? 55.462  54.170  41.883  1.00 30.07  ? 239 GLU E O   1 
ATOM   16115 C CB  . GLU E 1 239 ? 58.673  54.787  43.414  1.00 26.31  ? 239 GLU E CB  1 
ATOM   16116 C CG  . GLU E 1 239 ? 60.151  54.393  43.397  1.00 29.72  ? 239 GLU E CG  1 
ATOM   16117 C CD  . GLU E 1 239 ? 61.097  55.182  44.308  1.00 33.56  ? 239 GLU E CD  1 
ATOM   16118 O OE1 . GLU E 1 239 ? 62.219  54.672  44.416  1.00 28.52  ? 239 GLU E OE1 1 
ATOM   16119 O OE2 . GLU E 1 239 ? 60.796  56.270  44.878  1.00 33.54  ? 239 GLU E OE2 1 
ATOM   16120 N N   . GLY E 1 240 ? 55.995  53.613  43.988  1.00 28.84  ? 240 GLY E N   1 
ATOM   16121 C CA  . GLY E 1 240 ? 54.626  53.479  44.468  1.00 30.90  ? 240 GLY E CA  1 
ATOM   16122 C C   . GLY E 1 240 ? 54.216  54.532  45.517  1.00 29.63  ? 240 GLY E C   1 
ATOM   16123 O O   . GLY E 1 240 ? 53.104  54.480  46.025  1.00 29.88  ? 240 GLY E O   1 
ATOM   16124 N N   . GLY E 1 241 ? 55.070  55.508  45.826  1.00 27.52  ? 241 GLY E N   1 
ATOM   16125 C CA  . GLY E 1 241 ? 54.827  56.387  46.961  1.00 27.38  ? 241 GLY E CA  1 
ATOM   16126 C C   . GLY E 1 241 ? 54.069  57.653  46.572  1.00 27.88  ? 241 GLY E C   1 
ATOM   16127 O O   . GLY E 1 241 ? 53.451  58.290  47.429  1.00 28.90  ? 241 GLY E O   1 
ATOM   16128 N N   . ASN E 1 242 ? 54.100  57.988  45.272  1.00 27.45  ? 242 ASN E N   1 
ATOM   16129 C CA  . ASN E 1 242 ? 53.353  59.115  44.724  1.00 27.12  ? 242 ASN E CA  1 
ATOM   16130 C C   . ASN E 1 242 ? 51.842  58.886  44.901  1.00 26.60  ? 242 ASN E C   1 
ATOM   16131 O O   . ASN E 1 242 ? 51.331  57.750  44.944  1.00 23.38  ? 242 ASN E O   1 
ATOM   16132 C CB  . ASN E 1 242 ? 53.793  59.429  43.286  1.00 29.16  ? 242 ASN E CB  1 
ATOM   16133 C CG  . ASN E 1 242 ? 53.364  58.402  42.248  1.00 28.77  ? 242 ASN E CG  1 
ATOM   16134 O OD1 . ASN E 1 242 ? 52.167  58.258  41.961  1.00 32.29  ? 242 ASN E OD1 1 
ATOM   16135 N ND2 . ASN E 1 242 ? 54.308  57.666  41.675  1.00 27.18  ? 242 ASN E ND2 1 
ATOM   16136 N N   . VAL E 1 243 ? 51.114  60.006  44.956  1.00 27.24  ? 243 VAL E N   1 
ATOM   16137 C CA  . VAL E 1 243 ? 49.706  59.980  45.327  1.00 28.16  ? 243 VAL E CA  1 
ATOM   16138 C C   . VAL E 1 243 ? 48.935  58.979  44.472  1.00 27.62  ? 243 VAL E C   1 
ATOM   16139 O O   . VAL E 1 243 ? 48.223  58.145  45.037  1.00 23.15  ? 243 VAL E O   1 
ATOM   16140 C CB  . VAL E 1 243 ? 49.043  61.366  45.274  1.00 30.45  ? 243 VAL E CB  1 
ATOM   16141 C CG1 . VAL E 1 243 ? 47.533  61.272  45.482  1.00 29.37  ? 243 VAL E CG1 1 
ATOM   16142 C CG2 . VAL E 1 243 ? 49.661  62.305  46.305  1.00 32.31  ? 243 VAL E CG2 1 
ATOM   16143 N N   . SER E 1 244 ? 49.092  59.071  43.130  1.00 27.73  ? 244 SER E N   1 
ATOM   16144 C CA  . SER E 1 244 ? 48.300  58.255  42.227  1.00 27.33  ? 244 SER E CA  1 
ATOM   16145 C C   . SER E 1 244 ? 48.642  56.776  42.367  1.00 25.63  ? 244 SER E C   1 
ATOM   16146 O O   . SER E 1 244 ? 47.753  55.925  42.435  1.00 26.01  ? 244 SER E O   1 
ATOM   16147 C CB  . SER E 1 244 ? 48.314  58.721  40.776  1.00 28.75  ? 244 SER E CB  1 
ATOM   16148 O OG  . SER E 1 244 ? 49.527  59.275  40.307  1.00 30.66  ? 244 SER E OG  1 
ATOM   16149 N N   . ALA E 1 245 ? 49.927  56.444  42.389  1.00 24.92  ? 245 ALA E N   1 
ATOM   16150 C CA  . ALA E 1 245 ? 50.282  55.036  42.463  1.00 23.84  ? 245 ALA E CA  1 
ATOM   16151 C C   . ALA E 1 245 ? 49.889  54.494  43.834  1.00 23.95  ? 245 ALA E C   1 
ATOM   16152 O O   . ALA E 1 245 ? 49.500  53.343  43.936  1.00 22.57  ? 245 ALA E O   1 
ATOM   16153 C CB  . ALA E 1 245 ? 51.760  54.875  42.207  1.00 25.67  ? 245 ALA E CB  1 
ATOM   16154 N N   . HIS E 1 246 ? 50.004  55.343  44.875  1.00 24.13  ? 246 HIS E N   1 
ATOM   16155 C CA  . HIS E 1 246 ? 49.641  54.981  46.237  1.00 24.02  ? 246 HIS E CA  1 
ATOM   16156 C C   . HIS E 1 246 ? 48.120  54.796  46.367  1.00 23.83  ? 246 HIS E C   1 
ATOM   16157 O O   . HIS E 1 246 ? 47.656  53.772  46.881  1.00 24.04  ? 246 HIS E O   1 
ATOM   16158 C CB  . HIS E 1 246 ? 50.236  55.993  47.221  1.00 24.00  ? 246 HIS E CB  1 
ATOM   16159 C CG  . HIS E 1 246 ? 49.968  55.651  48.658  1.00 22.83  ? 246 HIS E CG  1 
ATOM   16160 N ND1 . HIS E 1 246 ? 50.139  56.553  49.685  1.00 19.80  ? 246 HIS E ND1 1 
ATOM   16161 C CD2 . HIS E 1 246 ? 49.561  54.499  49.229  1.00 22.13  ? 246 HIS E CD2 1 
ATOM   16162 C CE1 . HIS E 1 246 ? 49.848  55.960  50.830  1.00 21.33  ? 246 HIS E CE1 1 
ATOM   16163 N NE2 . HIS E 1 246 ? 49.481  54.715  50.582  1.00 21.61  ? 246 HIS E NE2 1 
ATOM   16164 N N   . THR E 1 247 ? 47.341  55.764  45.864  1.00 23.16  ? 247 THR E N   1 
ATOM   16165 C CA  . THR E 1 247 ? 45.888  55.627  45.796  1.00 21.06  ? 247 THR E CA  1 
ATOM   16166 C C   . THR E 1 247 ? 45.538  54.303  45.119  1.00 22.06  ? 247 THR E C   1 
ATOM   16167 O O   . THR E 1 247 ? 44.817  53.493  45.672  1.00 21.70  ? 247 THR E O   1 
ATOM   16168 C CB  . THR E 1 247 ? 45.266  56.839  45.097  1.00 20.42  ? 247 THR E CB  1 
ATOM   16169 O OG1 . THR E 1 247 ? 45.651  58.051  45.763  1.00 18.89  ? 247 THR E OG1 1 
ATOM   16170 C CG2 . THR E 1 247 ? 43.746  56.769  45.061  1.00 20.56  ? 247 THR E CG2 1 
ATOM   16171 N N   . ASN E 1 248 ? 46.094  54.034  43.942  1.00 23.77  ? 248 ASN E N   1 
ATOM   16172 C CA  . ASN E 1 248 ? 45.861  52.757  43.291  1.00 27.12  ? 248 ASN E CA  1 
ATOM   16173 C C   . ASN E 1 248 ? 46.067  51.580  44.259  1.00 32.02  ? 248 ASN E C   1 
ATOM   16174 O O   . ASN E 1 248 ? 45.201  50.719  44.436  1.00 30.10  ? 248 ASN E O   1 
ATOM   16175 C CB  . ASN E 1 248 ? 46.752  52.612  42.066  1.00 26.65  ? 248 ASN E CB  1 
ATOM   16176 C CG  . ASN E 1 248 ? 46.546  51.286  41.384  1.00 26.72  ? 248 ASN E CG  1 
ATOM   16177 O OD1 . ASN E 1 248 ? 47.476  50.479  41.219  1.00 28.19  ? 248 ASN E OD1 1 
ATOM   16178 N ND2 . ASN E 1 248 ? 45.313  51.053  40.978  1.00 26.42  ? 248 ASN E ND2 1 
ATOM   16179 N N   . LEU E 1 249 ? 47.256  51.504  44.868  1.00 36.25  ? 249 LEU E N   1 
ATOM   16180 C CA  . LEU E 1 249 ? 47.582  50.413  45.780  1.00 31.44  ? 249 LEU E CA  1 
ATOM   16181 C C   . LEU E 1 249 ? 46.597  50.356  46.962  1.00 30.93  ? 249 LEU E C   1 
ATOM   16182 O O   . LEU E 1 249 ? 46.181  49.260  47.374  1.00 29.41  ? 249 LEU E O   1 
ATOM   16183 C CB  . LEU E 1 249 ? 49.030  50.570  46.264  1.00 30.98  ? 249 LEU E CB  1 
ATOM   16184 C CG  . LEU E 1 249 ? 50.156  50.126  45.321  1.00 29.17  ? 249 LEU E CG  1 
ATOM   16185 C CD1 . LEU E 1 249 ? 51.512  50.480  45.912  1.00 27.66  ? 249 LEU E CD1 1 
ATOM   16186 C CD2 . LEU E 1 249 ? 50.105  48.632  45.030  1.00 31.69  ? 249 LEU E CD2 1 
ATOM   16187 N N   . LEU E 1 250 ? 46.269  51.531  47.535  1.00 28.04  ? 250 LEU E N   1 
ATOM   16188 C CA  . LEU E 1 250 ? 45.465  51.627  48.749  1.00 27.33  ? 250 LEU E CA  1 
ATOM   16189 C C   . LEU E 1 250 ? 44.082  51.008  48.549  1.00 28.36  ? 250 LEU E C   1 
ATOM   16190 O O   . LEU E 1 250 ? 43.668  50.117  49.283  1.00 28.30  ? 250 LEU E O   1 
ATOM   16191 C CB  . LEU E 1 250 ? 45.353  53.103  49.108  1.00 27.50  ? 250 LEU E CB  1 
ATOM   16192 C CG  . LEU E 1 250 ? 44.439  53.439  50.286  1.00 27.03  ? 250 LEU E CG  1 
ATOM   16193 C CD1 . LEU E 1 250 ? 44.650  52.477  51.418  1.00 27.46  ? 250 LEU E CD1 1 
ATOM   16194 C CD2 . LEU E 1 250 ? 44.693  54.861  50.772  1.00 26.78  ? 250 LEU E CD2 1 
ATOM   16195 N N   . VAL E 1 251 ? 43.384  51.474  47.509  1.00 29.11  ? 251 VAL E N   1 
ATOM   16196 C CA  . VAL E 1 251 ? 42.054  51.000  47.188  1.00 26.56  ? 251 VAL E CA  1 
ATOM   16197 C C   . VAL E 1 251 ? 42.115  49.547  46.723  1.00 26.87  ? 251 VAL E C   1 
ATOM   16198 O O   . VAL E 1 251 ? 41.190  48.782  46.980  1.00 26.69  ? 251 VAL E O   1 
ATOM   16199 C CB  . VAL E 1 251 ? 41.470  51.955  46.141  1.00 26.50  ? 251 VAL E CB  1 
ATOM   16200 C CG1 . VAL E 1 251 ? 40.230  51.376  45.480  1.00 28.92  ? 251 VAL E CG1 1 
ATOM   16201 C CG2 . VAL E 1 251 ? 41.190  53.325  46.754  1.00 26.57  ? 251 VAL E CG2 1 
ATOM   16202 N N   . ASN E 1 252 ? 43.203  49.164  46.046  1.00 27.40  ? 252 ASN E N   1 
ATOM   16203 C CA  . ASN E 1 252 ? 43.421  47.779  45.652  1.00 29.43  ? 252 ASN E CA  1 
ATOM   16204 C C   . ASN E 1 252 ? 43.534  46.874  46.891  1.00 29.03  ? 252 ASN E C   1 
ATOM   16205 O O   . ASN E 1 252 ? 43.107  45.707  46.898  1.00 27.31  ? 252 ASN E O   1 
ATOM   16206 C CB  . ASN E 1 252 ? 44.639  47.681  44.739  1.00 30.12  ? 252 ASN E CB  1 
ATOM   16207 C CG  . ASN E 1 252 ? 45.030  46.245  44.476  1.00 31.20  ? 252 ASN E CG  1 
ATOM   16208 O OD1 . ASN E 1 252 ? 45.720  45.617  45.293  1.00 29.67  ? 252 ASN E OD1 1 
ATOM   16209 N ND2 . ASN E 1 252 ? 44.605  45.722  43.333  1.00 32.33  ? 252 ASN E ND2 1 
ATOM   16210 N N   . SER E 1 253 ? 44.115  47.413  47.965  1.00 28.17  ? 253 SER E N   1 
ATOM   16211 C CA  . SER E 1 253 ? 44.328  46.612  49.161  1.00 28.18  ? 253 SER E CA  1 
ATOM   16212 C C   . SER E 1 253 ? 43.007  46.160  49.783  1.00 29.03  ? 253 SER E C   1 
ATOM   16213 O O   . SER E 1 253 ? 43.049  45.260  50.613  1.00 36.76  ? 253 SER E O   1 
ATOM   16214 C CB  . SER E 1 253 ? 45.188  47.332  50.181  1.00 25.72  ? 253 SER E CB  1 
ATOM   16215 O OG  . SER E 1 253 ? 44.479  48.348  50.870  1.00 22.63  ? 253 SER E OG  1 
ATOM   16216 N N   . ALA E 1 254 ? 41.858  46.744  49.383  1.00 26.30  ? 254 ALA E N   1 
ATOM   16217 C CA  . ALA E 1 254 ? 40.553  46.324  49.885  1.00 24.78  ? 254 ALA E CA  1 
ATOM   16218 C C   . ALA E 1 254 ? 39.877  45.323  48.959  1.00 26.38  ? 254 ALA E C   1 
ATOM   16219 O O   . ALA E 1 254 ? 38.707  45.026  49.152  1.00 30.95  ? 254 ALA E O   1 
ATOM   16220 C CB  . ALA E 1 254 ? 39.648  47.511  50.088  1.00 23.42  ? 254 ALA E CB  1 
ATOM   16221 N N   . TYR E 1 255 ? 40.594  44.852  47.938  1.00 28.53  ? 255 TYR E N   1 
ATOM   16222 C CA  . TYR E 1 255 ? 40.054  43.997  46.898  1.00 28.16  ? 255 TYR E CA  1 
ATOM   16223 C C   . TYR E 1 255 ? 39.055  44.736  46.001  1.00 26.30  ? 255 TYR E C   1 
ATOM   16224 O O   . TYR E 1 255 ? 38.255  44.097  45.322  1.00 26.68  ? 255 TYR E O   1 
ATOM   16225 C CB  . TYR E 1 255 ? 39.413  42.741  47.487  1.00 30.46  ? 255 TYR E CB  1 
ATOM   16226 C CG  . TYR E 1 255 ? 40.333  41.784  48.231  1.00 32.99  ? 255 TYR E CG  1 
ATOM   16227 C CD1 . TYR E 1 255 ? 41.708  41.950  48.290  1.00 36.14  ? 255 TYR E CD1 1 
ATOM   16228 C CD2 . TYR E 1 255 ? 39.796  40.665  48.876  1.00 35.93  ? 255 TYR E CD2 1 
ATOM   16229 C CE1 . TYR E 1 255 ? 42.503  41.047  48.997  1.00 37.09  ? 255 TYR E CE1 1 
ATOM   16230 C CE2 . TYR E 1 255 ? 40.574  39.765  49.584  1.00 30.07  ? 255 TYR E CE2 1 
ATOM   16231 C CZ  . TYR E 1 255 ? 41.935  39.953  49.632  1.00 32.32  ? 255 TYR E CZ  1 
ATOM   16232 O OH  . TYR E 1 255 ? 42.668  39.035  50.304  1.00 36.88  ? 255 TYR E OH  1 
ATOM   16233 N N   . SER E 1 256 ? 39.121  46.067  45.939  1.00 25.13  ? 256 SER E N   1 
ATOM   16234 C CA  . SER E 1 256 ? 38.457  46.794  44.866  1.00 28.02  ? 256 SER E CA  1 
ATOM   16235 C C   . SER E 1 256 ? 39.214  46.575  43.547  1.00 25.88  ? 256 SER E C   1 
ATOM   16236 O O   . SER E 1 256 ? 40.425  46.691  43.501  1.00 29.29  ? 256 SER E O   1 
ATOM   16237 C CB  . SER E 1 256 ? 38.330  48.294  45.168  1.00 28.88  ? 256 SER E CB  1 
ATOM   16238 O OG  . SER E 1 256 ? 37.641  48.581  46.378  1.00 27.46  ? 256 SER E OG  1 
ATOM   16239 N N   . ASP E 1 257 ? 38.488  46.334  42.457  1.00 26.68  ? 257 ASP E N   1 
ATOM   16240 C CA  . ASP E 1 257 ? 39.063  45.979  41.160  1.00 28.17  ? 257 ASP E CA  1 
ATOM   16241 C C   . ASP E 1 257 ? 39.801  47.174  40.545  1.00 25.39  ? 257 ASP E C   1 
ATOM   16242 O O   . ASP E 1 257 ? 39.789  48.268  41.112  1.00 22.53  ? 257 ASP E O   1 
ATOM   16243 C CB  . ASP E 1 257 ? 37.962  45.464  40.253  1.00 25.98  ? 257 ASP E CB  1 
ATOM   16244 C CG  . ASP E 1 257 ? 36.834  46.469  40.098  1.00 27.91  ? 257 ASP E CG  1 
ATOM   16245 O OD1 . ASP E 1 257 ? 37.094  47.572  39.549  1.00 29.48  ? 257 ASP E OD1 1 
ATOM   16246 O OD2 . ASP E 1 257 ? 35.744  46.187  40.619  1.00 28.93  ? 257 ASP E OD2 1 
ATOM   16247 N N   . ILE E 1 258 ? 40.428  46.943  39.379  1.00 25.52  ? 258 ILE E N   1 
ATOM   16248 C CA  . ILE E 1 258 ? 41.310  47.915  38.736  1.00 26.98  ? 258 ILE E CA  1 
ATOM   16249 C C   . ILE E 1 258 ? 40.555  49.177  38.303  1.00 25.99  ? 258 ILE E C   1 
ATOM   16250 O O   . ILE E 1 258 ? 41.138  50.263  38.255  1.00 27.29  ? 258 ILE E O   1 
ATOM   16251 C CB  . ILE E 1 258 ? 42.060  47.299  37.537  1.00 31.35  ? 258 ILE E CB  1 
ATOM   16252 C CG1 . ILE E 1 258 ? 43.145  48.234  37.004  1.00 35.08  ? 258 ILE E CG1 1 
ATOM   16253 C CG2 . ILE E 1 258 ? 41.098  46.918  36.413  1.00 33.30  ? 258 ILE E CG2 1 
ATOM   16254 C CD1 . ILE E 1 258 ? 44.071  48.776  38.086  1.00 35.89  ? 258 ILE E CD1 1 
ATOM   16255 N N   . TYR E 1 259 ? 39.275  49.040  37.936  1.00 24.99  ? 259 TYR E N   1 
ATOM   16256 C CA  . TYR E 1 259 ? 38.483  50.184  37.520  1.00 21.57  ? 259 TYR E CA  1 
ATOM   16257 C C   . TYR E 1 259 ? 38.241  51.124  38.692  1.00 22.20  ? 259 TYR E C   1 
ATOM   16258 O O   . TYR E 1 259 ? 38.258  52.342  38.513  1.00 21.85  ? 259 TYR E O   1 
ATOM   16259 C CB  . TYR E 1 259 ? 37.154  49.726  36.932  1.00 21.81  ? 259 TYR E CB  1 
ATOM   16260 C CG  . TYR E 1 259 ? 37.305  48.907  35.661  1.00 21.70  ? 259 TYR E CG  1 
ATOM   16261 C CD1 . TYR E 1 259 ? 37.515  49.515  34.420  1.00 23.36  ? 259 TYR E CD1 1 
ATOM   16262 C CD2 . TYR E 1 259 ? 37.217  47.524  35.697  1.00 22.07  ? 259 TYR E CD2 1 
ATOM   16263 C CE1 . TYR E 1 259 ? 37.635  48.763  33.255  1.00 22.14  ? 259 TYR E CE1 1 
ATOM   16264 C CE2 . TYR E 1 259 ? 37.360  46.760  34.542  1.00 22.99  ? 259 TYR E CE2 1 
ATOM   16265 C CZ  . TYR E 1 259 ? 37.561  47.380  33.322  1.00 22.47  ? 259 TYR E CZ  1 
ATOM   16266 O OH  . TYR E 1 259 ? 37.687  46.588  32.223  1.00 24.54  ? 259 TYR E OH  1 
ATOM   16267 N N   . ARG E 1 260 ? 37.991  50.573  39.888  1.00 23.75  ? 260 ARG E N   1 
ATOM   16268 C CA  . ARG E 1 260 ? 37.796  51.414  41.065  1.00 24.12  ? 260 ARG E CA  1 
ATOM   16269 C C   . ARG E 1 260 ? 39.126  52.013  41.534  1.00 27.35  ? 260 ARG E C   1 
ATOM   16270 O O   . ARG E 1 260 ? 39.184  53.205  41.880  1.00 25.49  ? 260 ARG E O   1 
ATOM   16271 C CB  . ARG E 1 260 ? 37.135  50.628  42.196  1.00 27.04  ? 260 ARG E CB  1 
ATOM   16272 C CG  . ARG E 1 260 ? 35.607  50.621  42.213  1.00 30.00  ? 260 ARG E CG  1 
ATOM   16273 C CD  . ARG E 1 260 ? 34.994  49.404  42.888  1.00 28.32  ? 260 ARG E CD  1 
ATOM   16274 N NE  . ARG E 1 260 ? 33.533  49.468  42.887  1.00 30.54  ? 260 ARG E NE  1 
ATOM   16275 C CZ  . ARG E 1 260 ? 32.743  48.453  43.260  1.00 32.09  ? 260 ARG E CZ  1 
ATOM   16276 N NH1 . ARG E 1 260 ? 31.439  48.637  43.346  1.00 32.46  ? 260 ARG E NH1 1 
ATOM   16277 N NH2 . ARG E 1 260 ? 33.237  47.273  43.587  1.00 28.25  ? 260 ARG E NH2 1 
ATOM   16278 N N   . SER E 1 261 ? 40.212  51.211  41.513  1.00 27.10  ? 261 SER E N   1 
ATOM   16279 C CA  . SER E 1 261 ? 41.493  51.680  42.046  1.00 27.95  ? 261 SER E CA  1 
ATOM   16280 C C   . SER E 1 261 ? 42.127  52.701  41.117  1.00 25.88  ? 261 SER E C   1 
ATOM   16281 O O   . SER E 1 261 ? 42.669  53.724  41.569  1.00 25.61  ? 261 SER E O   1 
ATOM   16282 C CB  . SER E 1 261 ? 42.465  50.558  42.359  1.00 26.84  ? 261 SER E CB  1 
ATOM   16283 O OG  . SER E 1 261 ? 42.895  49.863  41.203  1.00 28.94  ? 261 SER E OG  1 
ATOM   16284 N N   . PHE E 1 262 ? 42.028  52.409  39.817  1.00 25.04  ? 262 PHE E N   1 
ATOM   16285 C CA  . PHE E 1 262 ? 42.661  53.264  38.847  1.00 24.50  ? 262 PHE E CA  1 
ATOM   16286 C C   . PHE E 1 262 ? 41.823  54.534  38.725  1.00 25.02  ? 262 PHE E C   1 
ATOM   16287 O O   . PHE E 1 262 ? 42.417  55.612  38.698  1.00 29.65  ? 262 PHE E O   1 
ATOM   16288 C CB  . PHE E 1 262 ? 42.980  52.528  37.545  1.00 26.32  ? 262 PHE E CB  1 
ATOM   16289 C CG  . PHE E 1 262 ? 43.840  53.442  36.697  1.00 26.55  ? 262 PHE E CG  1 
ATOM   16290 C CD1 . PHE E 1 262 ? 45.151  53.703  37.056  1.00 27.76  ? 262 PHE E CD1 1 
ATOM   16291 C CD2 . PHE E 1 262 ? 43.282  54.181  35.659  1.00 28.09  ? 262 PHE E CD2 1 
ATOM   16292 C CE1 . PHE E 1 262 ? 45.905  54.627  36.337  1.00 28.11  ? 262 PHE E CE1 1 
ATOM   16293 C CE2 . PHE E 1 262 ? 44.043  55.102  34.942  1.00 27.35  ? 262 PHE E CE2 1 
ATOM   16294 C CZ  . PHE E 1 262 ? 45.348  55.318  35.281  1.00 26.55  ? 262 PHE E CZ  1 
ATOM   16295 N N   . SER E 1 263 ? 40.475  54.461  38.729  1.00 23.14  ? 263 SER E N   1 
ATOM   16296 C CA  . SER E 1 263 ? 39.701  55.710  38.654  1.00 25.64  ? 263 SER E CA  1 
ATOM   16297 C C   . SER E 1 263 ? 40.005  56.602  39.860  1.00 24.88  ? 263 SER E C   1 
ATOM   16298 O O   . SER E 1 263 ? 40.192  57.804  39.722  1.00 23.92  ? 263 SER E O   1 
ATOM   16299 C CB  . SER E 1 263 ? 38.180  55.547  38.451  1.00 26.28  ? 263 SER E CB  1 
ATOM   16300 O OG  . SER E 1 263 ? 37.567  54.576  39.290  1.00 28.42  ? 263 SER E OG  1 
ATOM   16301 N N   . ALA E 1 264 ? 40.095  55.982  41.040  1.00 27.94  ? 264 ALA E N   1 
ATOM   16302 C CA  . ALA E 1 264 ? 40.508  56.635  42.279  1.00 27.42  ? 264 ALA E CA  1 
ATOM   16303 C C   . ALA E 1 264 ? 41.902  57.235  42.157  1.00 24.29  ? 264 ALA E C   1 
ATOM   16304 O O   . ALA E 1 264 ? 42.117  58.380  42.555  1.00 24.33  ? 264 ALA E O   1 
ATOM   16305 C CB  . ALA E 1 264 ? 40.449  55.649  43.426  1.00 27.70  ? 264 ALA E CB  1 
ATOM   16306 N N   . ALA E 1 265 ? 42.838  56.481  41.579  1.00 22.82  ? 265 ALA E N   1 
ATOM   16307 C CA  . ALA E 1 265 ? 44.179  57.019  41.396  1.00 24.37  ? 265 ALA E CA  1 
ATOM   16308 C C   . ALA E 1 265 ? 44.146  58.294  40.537  1.00 25.89  ? 265 ALA E C   1 
ATOM   16309 O O   . ALA E 1 265 ? 44.834  59.291  40.849  1.00 22.58  ? 265 ALA E O   1 
ATOM   16310 C CB  . ALA E 1 265 ? 45.059  55.934  40.815  1.00 25.77  ? 265 ALA E CB  1 
ATOM   16311 N N   . MET E 1 266 ? 43.339  58.248  39.447  1.00 22.78  ? 266 MET E N   1 
ATOM   16312 C CA  . MET E 1 266 ? 43.197  59.397  38.577  1.00 23.23  ? 266 MET E CA  1 
ATOM   16313 C C   . MET E 1 266 ? 42.613  60.602  39.320  1.00 24.87  ? 266 MET E C   1 
ATOM   16314 O O   . MET E 1 266 ? 42.931  61.736  38.943  1.00 28.02  ? 266 MET E O   1 
ATOM   16315 C CB  . MET E 1 266 ? 42.362  59.069  37.339  1.00 24.66  ? 266 MET E CB  1 
ATOM   16316 C CG  . MET E 1 266 ? 43.000  58.067  36.376  1.00 24.62  ? 266 MET E CG  1 
ATOM   16317 S SD  . MET E 1 266 ? 44.592  58.639  35.750  1.00 23.88  ? 266 MET E SD  1 
ATOM   16318 C CE  . MET E 1 266 ? 45.769  57.977  36.934  1.00 26.86  ? 266 MET E CE  1 
ATOM   16319 N N   . ASN E 1 267 ? 41.783  60.394  40.362  1.00 23.37  ? 267 ASN E N   1 
ATOM   16320 C CA  . ASN E 1 267 ? 41.246  61.537  41.107  1.00 26.41  ? 267 ASN E CA  1 
ATOM   16321 C C   . ASN E 1 267 ? 42.371  62.253  41.844  1.00 27.03  ? 267 ASN E C   1 
ATOM   16322 O O   . ASN E 1 267 ? 42.340  63.470  42.026  1.00 26.23  ? 267 ASN E O   1 
ATOM   16323 C CB  . ASN E 1 267 ? 40.160  61.190  42.134  1.00 27.38  ? 267 ASN E CB  1 
ATOM   16324 C CG  . ASN E 1 267 ? 38.770  60.967  41.557  1.00 25.14  ? 267 ASN E CG  1 
ATOM   16325 O OD1 . ASN E 1 267 ? 38.557  61.076  40.349  1.00 24.78  ? 267 ASN E OD1 1 
ATOM   16326 N ND2 . ASN E 1 267 ? 37.803  60.621  42.392  1.00 22.96  ? 267 ASN E ND2 1 
ATOM   16327 N N   . GLY E 1 268 ? 43.344  61.458  42.300  1.00 27.76  ? 268 GLY E N   1 
ATOM   16328 C CA  . GLY E 1 268 ? 44.542  61.993  42.923  1.00 27.60  ? 268 GLY E CA  1 
ATOM   16329 C C   . GLY E 1 268 ? 45.451  62.673  41.904  1.00 27.01  ? 268 GLY E C   1 
ATOM   16330 O O   . GLY E 1 268 ? 45.997  63.732  42.183  1.00 27.74  ? 268 GLY E O   1 
ATOM   16331 N N   . LEU E 1 269 ? 45.590  62.086  40.706  1.00 28.39  ? 269 LEU E N   1 
ATOM   16332 C CA  . LEU E 1 269 ? 46.383  62.735  39.670  1.00 25.42  ? 269 LEU E CA  1 
ATOM   16333 C C   . LEU E 1 269 ? 45.777  64.092  39.336  1.00 23.52  ? 269 LEU E C   1 
ATOM   16334 O O   . LEU E 1 269 ? 46.471  65.059  39.090  1.00 29.38  ? 269 LEU E O   1 
ATOM   16335 C CB  . LEU E 1 269 ? 46.498  61.829  38.448  1.00 25.91  ? 269 LEU E CB  1 
ATOM   16336 C CG  . LEU E 1 269 ? 47.580  62.203  37.425  1.00 27.80  ? 269 LEU E CG  1 
ATOM   16337 C CD1 . LEU E 1 269 ? 48.946  62.418  38.030  1.00 30.24  ? 269 LEU E CD1 1 
ATOM   16338 C CD2 . LEU E 1 269 ? 47.682  61.088  36.409  1.00 30.30  ? 269 LEU E CD2 1 
ATOM   16339 N N   . ALA E 1 270 ? 44.460  64.204  39.402  1.00 23.18  ? 270 ALA E N   1 
ATOM   16340 C CA  . ALA E 1 270 ? 43.807  65.447  39.032  1.00 22.47  ? 270 ALA E CA  1 
ATOM   16341 C C   . ALA E 1 270 ? 44.193  66.588  39.960  1.00 24.99  ? 270 ALA E C   1 
ATOM   16342 O O   . ALA E 1 270 ? 43.831  67.730  39.673  1.00 26.30  ? 270 ALA E O   1 
ATOM   16343 C CB  . ALA E 1 270 ? 42.304  65.256  39.070  1.00 22.47  ? 270 ALA E CB  1 
ATOM   16344 N N   . GLY E 1 271 ? 44.829  66.259  41.099  1.00 24.47  ? 271 GLY E N   1 
ATOM   16345 C CA  . GLY E 1 271 ? 45.196  67.242  42.105  1.00 25.19  ? 271 GLY E CA  1 
ATOM   16346 C C   . GLY E 1 271 ? 46.282  68.214  41.636  1.00 26.31  ? 271 GLY E C   1 
ATOM   16347 O O   . GLY E 1 271 ? 47.314  67.831  41.074  1.00 25.77  ? 271 GLY E O   1 
ATOM   16348 N N   . PRO E 1 272 ? 46.061  69.522  41.849  1.00 24.71  ? 272 PRO E N   1 
ATOM   16349 C CA  . PRO E 1 272 ? 47.038  70.529  41.458  1.00 27.80  ? 272 PRO E CA  1 
ATOM   16350 C C   . PRO E 1 272 ? 48.500  70.291  41.838  1.00 32.83  ? 272 PRO E C   1 
ATOM   16351 O O   . PRO E 1 272 ? 49.383  70.889  41.218  1.00 38.38  ? 272 PRO E O   1 
ATOM   16352 C CB  . PRO E 1 272 ? 46.484  71.760  42.159  1.00 27.61  ? 272 PRO E CB  1 
ATOM   16353 C CG  . PRO E 1 272 ? 44.993  71.544  42.219  1.00 26.76  ? 272 PRO E CG  1 
ATOM   16354 C CD  . PRO E 1 272 ? 44.833  70.077  42.425  1.00 25.64  ? 272 PRO E CD  1 
ATOM   16355 N N   . LEU E 1 273 ? 48.749  69.492  42.892  1.00 33.70  ? 273 LEU E N   1 
ATOM   16356 C CA  . LEU E 1 273 ? 50.088  69.317  43.441  1.00 33.95  ? 273 LEU E CA  1 
ATOM   16357 C C   . LEU E 1 273 ? 50.738  68.084  42.824  1.00 33.48  ? 273 LEU E C   1 
ATOM   16358 O O   . LEU E 1 273 ? 51.917  67.826  43.079  1.00 38.16  ? 273 LEU E O   1 
ATOM   16359 C CB  . LEU E 1 273 ? 50.085  69.176  44.974  1.00 36.64  ? 273 LEU E CB  1 
ATOM   16360 C CG  . LEU E 1 273 ? 49.611  70.383  45.796  1.00 37.39  ? 273 LEU E CG  1 
ATOM   16361 C CD1 . LEU E 1 273 ? 49.785  70.173  47.293  1.00 35.88  ? 273 LEU E CD1 1 
ATOM   16362 C CD2 . LEU E 1 273 ? 50.311  71.666  45.367  1.00 39.47  ? 273 LEU E CD2 1 
ATOM   16363 N N   . HIS E 1 274 ? 49.952  67.316  42.060  1.00 29.58  ? 274 HIS E N   1 
ATOM   16364 C CA  . HIS E 1 274 ? 50.419  66.067  41.496  1.00 29.04  ? 274 HIS E CA  1 
ATOM   16365 C C   . HIS E 1 274 ? 50.449  66.119  39.963  1.00 32.06  ? 274 HIS E C   1 
ATOM   16366 O O   . HIS E 1 274 ? 51.293  65.455  39.369  1.00 32.73  ? 274 HIS E O   1 
ATOM   16367 C CB  . HIS E 1 274 ? 49.567  64.916  42.039  1.00 27.25  ? 274 HIS E CB  1 
ATOM   16368 C CG  . HIS E 1 274 ? 50.023  63.531  41.696  1.00 28.95  ? 274 HIS E CG  1 
ATOM   16369 N ND1 . HIS E 1 274 ? 51.286  63.194  41.261  1.00 29.89  ? 274 HIS E ND1 1 
ATOM   16370 C CD2 . HIS E 1 274 ? 49.339  62.362  41.758  1.00 32.81  ? 274 HIS E CD2 1 
ATOM   16371 C CE1 . HIS E 1 274 ? 51.361  61.873  41.096  1.00 30.06  ? 274 HIS E CE1 1 
ATOM   16372 N NE2 . HIS E 1 274 ? 50.178  61.355  41.357  1.00 32.94  ? 274 HIS E NE2 1 
ATOM   16373 N N   . GLY E 1 275 ? 49.550  66.859  39.288  1.00 32.04  ? 275 GLY E N   1 
ATOM   16374 C CA  . GLY E 1 275 ? 49.260  66.545  37.885  1.00 32.15  ? 275 GLY E CA  1 
ATOM   16375 C C   . GLY E 1 275 ? 49.603  67.632  36.852  1.00 30.68  ? 275 GLY E C   1 
ATOM   16376 O O   . GLY E 1 275 ? 49.439  67.392  35.654  1.00 35.79  ? 275 GLY E O   1 
ATOM   16377 N N   . LEU E 1 276 ? 50.072  68.800  37.300  1.00 28.79  ? 276 LEU E N   1 
ATOM   16378 C CA  . LEU E 1 276 ? 50.094  70.010  36.491  1.00 31.00  ? 276 LEU E CA  1 
ATOM   16379 C C   . LEU E 1 276 ? 51.496  70.431  36.044  1.00 31.05  ? 276 LEU E C   1 
ATOM   16380 O O   . LEU E 1 276 ? 51.597  71.393  35.290  1.00 38.90  ? 276 LEU E O   1 
ATOM   16381 C CB  . LEU E 1 276 ? 49.505  71.157  37.320  1.00 33.25  ? 276 LEU E CB  1 
ATOM   16382 C CG  . LEU E 1 276 ? 48.014  71.092  37.666  1.00 35.89  ? 276 LEU E CG  1 
ATOM   16383 C CD1 . LEU E 1 276 ? 47.627  72.434  38.316  1.00 37.74  ? 276 LEU E CD1 1 
ATOM   16384 C CD2 . LEU E 1 276 ? 47.112  70.789  36.448  1.00 34.88  ? 276 LEU E CD2 1 
ATOM   16385 N N   . ALA E 1 277 ? 52.573  69.800  36.532  1.00 27.79  ? 277 ALA E N   1 
ATOM   16386 C CA  . ALA E 1 277 ? 53.905  70.387  36.416  1.00 27.69  ? 277 ALA E CA  1 
ATOM   16387 C C   . ALA E 1 277 ? 54.347  70.671  34.968  1.00 29.51  ? 277 ALA E C   1 
ATOM   16388 O O   . ALA E 1 277 ? 54.958  71.718  34.741  1.00 29.86  ? 277 ALA E O   1 
ATOM   16389 C CB  . ALA E 1 277 ? 54.915  69.523  37.153  1.00 27.06  ? 277 ALA E CB  1 
ATOM   16390 N N   . ASN E 1 278 ? 54.078  69.775  33.987  1.00 26.41  ? 278 ASN E N   1 
ATOM   16391 C CA  . ASN E 1 278 ? 54.536  70.023  32.624  1.00 26.13  ? 278 ASN E CA  1 
ATOM   16392 C C   . ASN E 1 278 ? 53.789  71.177  31.966  1.00 26.71  ? 278 ASN E C   1 
ATOM   16393 O O   . ASN E 1 278 ? 54.345  71.872  31.118  1.00 29.61  ? 278 ASN E O   1 
ATOM   16394 C CB  . ASN E 1 278 ? 54.572  68.792  31.721  1.00 29.00  ? 278 ASN E CB  1 
ATOM   16395 C CG  . ASN E 1 278 ? 53.243  68.295  31.219  1.00 30.81  ? 278 ASN E CG  1 
ATOM   16396 O OD1 . ASN E 1 278 ? 52.228  68.416  31.910  1.00 36.74  ? 278 ASN E OD1 1 
ATOM   16397 N ND2 . ASN E 1 278 ? 53.239  67.681  30.043  1.00 32.18  ? 278 ASN E ND2 1 
ATOM   16398 N N   . GLN E 1 279 ? 52.530  71.385  32.348  1.00 26.41  ? 279 GLN E N   1 
ATOM   16399 C CA  . GLN E 1 279 ? 51.775  72.526  31.866  1.00 27.07  ? 279 GLN E CA  1 
ATOM   16400 C C   . GLN E 1 279 ? 52.386  73.814  32.404  1.00 29.33  ? 279 GLN E C   1 
ATOM   16401 O O   . GLN E 1 279 ? 52.512  74.784  31.654  1.00 30.74  ? 279 GLN E O   1 
ATOM   16402 C CB  . GLN E 1 279 ? 50.321  72.489  32.324  1.00 29.42  ? 279 GLN E CB  1 
ATOM   16403 C CG  . GLN E 1 279 ? 49.717  71.098  32.207  1.00 30.93  ? 279 GLN E CG  1 
ATOM   16404 C CD  . GLN E 1 279 ? 48.298  71.015  32.711  1.00 32.35  ? 279 GLN E CD  1 
ATOM   16405 O OE1 . GLN E 1 279 ? 47.613  72.023  32.962  1.00 34.57  ? 279 GLN E OE1 1 
ATOM   16406 N NE2 . GLN E 1 279 ? 47.831  69.780  32.784  1.00 34.09  ? 279 GLN E NE2 1 
ATOM   16407 N N   . GLU E 1 280 ? 52.740  73.813  33.701  1.00 29.54  ? 280 GLU E N   1 
ATOM   16408 C CA  . GLU E 1 280 ? 53.296  74.987  34.356  1.00 33.39  ? 280 GLU E CA  1 
ATOM   16409 C C   . GLU E 1 280 ? 54.596  75.371  33.668  1.00 30.79  ? 280 GLU E C   1 
ATOM   16410 O O   . GLU E 1 280 ? 54.842  76.550  33.406  1.00 31.21  ? 280 GLU E O   1 
ATOM   16411 C CB  . GLU E 1 280 ? 53.490  74.788  35.866  1.00 42.26  ? 280 GLU E CB  1 
ATOM   16412 C CG  . GLU E 1 280 ? 52.235  75.089  36.691  1.00 45.91  ? 280 GLU E CG  1 
ATOM   16413 C CD  . GLU E 1 280 ? 52.113  74.320  37.990  1.00 50.60  ? 280 GLU E CD  1 
ATOM   16414 O OE1 . GLU E 1 280 ? 51.095  74.510  38.688  1.00 53.76  ? 280 GLU E OE1 1 
ATOM   16415 O OE2 . GLU E 1 280 ? 53.026  73.522  38.285  1.00 51.56  ? 280 GLU E OE2 1 
ATOM   16416 N N   . VAL E 1 281 ? 55.398  74.355  33.346  1.00 27.53  ? 281 VAL E N   1 
ATOM   16417 C CA  . VAL E 1 281 ? 56.660  74.584  32.671  1.00 26.89  ? 281 VAL E CA  1 
ATOM   16418 C C   . VAL E 1 281 ? 56.383  75.203  31.311  1.00 26.35  ? 281 VAL E C   1 
ATOM   16419 O O   . VAL E 1 281 ? 56.949  76.224  30.958  1.00 28.69  ? 281 VAL E O   1 
ATOM   16420 C CB  . VAL E 1 281 ? 57.433  73.258  32.562  1.00 29.23  ? 281 VAL E CB  1 
ATOM   16421 C CG1 . VAL E 1 281 ? 58.486  73.308  31.463  1.00 29.63  ? 281 VAL E CG1 1 
ATOM   16422 C CG2 . VAL E 1 281 ? 58.028  72.856  33.915  1.00 27.77  ? 281 VAL E CG2 1 
ATOM   16423 N N   . LEU E 1 282 ? 55.482  74.594  30.551  1.00 27.54  ? 282 LEU E N   1 
ATOM   16424 C CA  . LEU E 1 282 ? 55.249  75.051  29.192  1.00 28.99  ? 282 LEU E CA  1 
ATOM   16425 C C   . LEU E 1 282 ? 54.771  76.497  29.194  1.00 29.47  ? 282 LEU E C   1 
ATOM   16426 O O   . LEU E 1 282 ? 55.179  77.274  28.349  1.00 34.81  ? 282 LEU E O   1 
ATOM   16427 C CB  . LEU E 1 282 ? 54.257  74.165  28.443  1.00 28.76  ? 282 LEU E CB  1 
ATOM   16428 C CG  . LEU E 1 282 ? 53.833  74.695  27.072  1.00 30.96  ? 282 LEU E CG  1 
ATOM   16429 C CD1 . LEU E 1 282 ? 55.047  74.811  26.188  1.00 31.30  ? 282 LEU E CD1 1 
ATOM   16430 C CD2 . LEU E 1 282 ? 52.788  73.840  26.396  1.00 32.36  ? 282 LEU E CD2 1 
ATOM   16431 N N   . ARG E 1 283 ? 53.852  76.848  30.090  1.00 31.48  ? 283 ARG E N   1 
ATOM   16432 C CA  . ARG E 1 283 ? 53.358  78.219  30.137  1.00 32.28  ? 283 ARG E CA  1 
ATOM   16433 C C   . ARG E 1 283 ? 54.504  79.133  30.532  1.00 30.55  ? 283 ARG E C   1 
ATOM   16434 O O   . ARG E 1 283 ? 54.521  80.284  30.129  1.00 28.79  ? 283 ARG E O   1 
ATOM   16435 C CB  . ARG E 1 283 ? 52.215  78.452  31.133  1.00 33.03  ? 283 ARG E CB  1 
ATOM   16436 C CG  . ARG E 1 283 ? 50.904  77.756  30.778  1.00 35.09  ? 283 ARG E CG  1 
ATOM   16437 C CD  . ARG E 1 283 ? 49.847  77.964  31.865  1.00 37.42  ? 283 ARG E CD  1 
ATOM   16438 N NE  . ARG E 1 283 ? 48.686  77.072  31.820  1.00 40.66  ? 283 ARG E NE  1 
ATOM   16439 C CZ  . ARG E 1 283 ? 47.582  77.271  31.098  1.00 45.63  ? 283 ARG E CZ  1 
ATOM   16440 N NH1 . ARG E 1 283 ? 47.528  78.229  30.182  1.00 45.71  ? 283 ARG E NH1 1 
ATOM   16441 N NH2 . ARG E 1 283 ? 46.536  76.480  31.283  1.00 42.10  ? 283 ARG E NH2 1 
ATOM   16442 N N   . TRP E 1 284 ? 55.438  78.616  31.344  1.00 32.21  ? 284 TRP E N   1 
ATOM   16443 C CA  . TRP E 1 284 ? 56.578  79.413  31.745  1.00 33.95  ? 284 TRP E CA  1 
ATOM   16444 C C   . TRP E 1 284 ? 57.420  79.707  30.500  1.00 36.85  ? 284 TRP E C   1 
ATOM   16445 O O   . TRP E 1 284 ? 57.753  80.870  30.244  1.00 35.82  ? 284 TRP E O   1 
ATOM   16446 C CB  . TRP E 1 284 ? 57.352  78.711  32.867  1.00 36.45  ? 284 TRP E CB  1 
ATOM   16447 C CG  . TRP E 1 284 ? 58.458  79.525  33.498  1.00 40.64  ? 284 TRP E CG  1 
ATOM   16448 C CD1 . TRP E 1 284 ? 58.334  80.514  34.434  1.00 42.36  ? 284 TRP E CD1 1 
ATOM   16449 C CD2 . TRP E 1 284 ? 59.879  79.373  33.272  1.00 42.03  ? 284 TRP E CD2 1 
ATOM   16450 N NE1 . TRP E 1 284 ? 59.563  81.015  34.773  1.00 41.19  ? 284 TRP E NE1 1 
ATOM   16451 C CE2 . TRP E 1 284 ? 60.530  80.335  34.081  1.00 42.30  ? 284 TRP E CE2 1 
ATOM   16452 C CE3 . TRP E 1 284 ? 60.656  78.534  32.460  1.00 38.64  ? 284 TRP E CE3 1 
ATOM   16453 C CZ2 . TRP E 1 284 ? 61.915  80.478  34.090  1.00 40.69  ? 284 TRP E CZ2 1 
ATOM   16454 C CZ3 . TRP E 1 284 ? 62.023  78.673  32.476  1.00 40.13  ? 284 TRP E CZ3 1 
ATOM   16455 C CH2 . TRP E 1 284 ? 62.641  79.634  33.281  1.00 41.61  ? 284 TRP E CH2 1 
ATOM   16456 N N   . ILE E 1 285 ? 57.688  78.672  29.683  1.00 30.16  ? 285 ILE E N   1 
ATOM   16457 C CA  . ILE E 1 285 ? 58.486  78.854  28.487  1.00 28.27  ? 285 ILE E CA  1 
ATOM   16458 C C   . ILE E 1 285 ? 57.754  79.830  27.564  1.00 32.16  ? 285 ILE E C   1 
ATOM   16459 O O   . ILE E 1 285 ? 58.365  80.661  26.876  1.00 28.83  ? 285 ILE E O   1 
ATOM   16460 C CB  . ILE E 1 285 ? 58.763  77.516  27.780  1.00 27.68  ? 285 ILE E CB  1 
ATOM   16461 C CG1 . ILE E 1 285 ? 59.552  76.531  28.627  1.00 27.82  ? 285 ILE E CG1 1 
ATOM   16462 C CG2 . ILE E 1 285 ? 59.470  77.762  26.446  1.00 29.37  ? 285 ILE E CG2 1 
ATOM   16463 C CD1 . ILE E 1 285 ? 60.983  76.960  28.915  1.00 27.92  ? 285 ILE E CD1 1 
ATOM   16464 N N   . GLN E 1 286 ? 56.419  79.711  27.535  1.00 37.02  ? 286 GLN E N   1 
ATOM   16465 C CA  . GLN E 1 286 ? 55.592  80.521  26.640  1.00 36.30  ? 286 GLN E CA  1 
ATOM   16466 C C   . GLN E 1 286 ? 55.628  82.001  27.025  1.00 33.82  ? 286 GLN E C   1 
ATOM   16467 O O   . GLN E 1 286 ? 55.642  82.848  26.137  1.00 32.90  ? 286 GLN E O   1 
ATOM   16468 C CB  . GLN E 1 286 ? 54.175  79.957  26.547  1.00 33.73  ? 286 GLN E CB  1 
ATOM   16469 C CG  . GLN E 1 286 ? 54.134  78.665  25.744  1.00 34.71  ? 286 GLN E CG  1 
ATOM   16470 C CD  . GLN E 1 286 ? 52.746  78.112  25.560  1.00 33.12  ? 286 GLN E CD  1 
ATOM   16471 O OE1 . GLN E 1 286 ? 52.279  77.941  24.432  1.00 44.21  ? 286 GLN E OE1 1 
ATOM   16472 N NE2 . GLN E 1 286 ? 52.089  77.809  26.661  1.00 30.22  ? 286 GLN E NE2 1 
ATOM   16473 N N   . MET E 1 287 ? 55.661  82.273  28.335  1.00 33.14  ? 287 MET E N   1 
ATOM   16474 C CA  . MET E 1 287 ? 55.765  83.613  28.891  1.00 38.32  ? 287 MET E CA  1 
ATOM   16475 C C   . MET E 1 287 ? 57.120  84.240  28.558  1.00 41.26  ? 287 MET E C   1 
ATOM   16476 O O   . MET E 1 287 ? 57.166  85.423  28.221  1.00 53.32  ? 287 MET E O   1 
ATOM   16477 C CB  . MET E 1 287 ? 55.513  83.574  30.409  1.00 37.28  ? 287 MET E CB  1 
ATOM   16478 C CG  . MET E 1 287 ? 55.804  84.863  31.163  1.00 36.93  ? 287 MET E CG  1 
ATOM   16479 S SD  . MET E 1 287 ? 57.513  85.070  31.722  1.00 44.79  ? 287 MET E SD  1 
ATOM   16480 C CE  . MET E 1 287 ? 58.008  83.567  32.584  1.00 38.91  ? 287 MET E CE  1 
ATOM   16481 N N   . LEU E 1 288 ? 58.209  83.463  28.667  1.00 42.78  ? 288 LEU E N   1 
ATOM   16482 C CA  . LEU E 1 288 ? 59.545  83.934  28.302  1.00 41.72  ? 288 LEU E CA  1 
ATOM   16483 C C   . LEU E 1 288 ? 59.554  84.385  26.840  1.00 41.29  ? 288 LEU E C   1 
ATOM   16484 O O   . LEU E 1 288 ? 60.058  85.451  26.537  1.00 40.02  ? 288 LEU E O   1 
ATOM   16485 C CB  . LEU E 1 288 ? 60.620  82.868  28.519  1.00 40.28  ? 288 LEU E CB  1 
ATOM   16486 C CG  . LEU E 1 288 ? 60.984  82.495  29.962  1.00 38.72  ? 288 LEU E CG  1 
ATOM   16487 C CD1 . LEU E 1 288 ? 61.996  81.366  29.904  1.00 37.78  ? 288 LEU E CD1 1 
ATOM   16488 C CD2 . LEU E 1 288 ? 61.541  83.636  30.804  1.00 40.15  ? 288 LEU E CD2 1 
ATOM   16489 N N   . TYR E 1 289 ? 58.969  83.589  25.937  1.00 42.62  ? 289 TYR E N   1 
ATOM   16490 C CA  . TYR E 1 289 ? 58.969  83.912  24.516  1.00 44.34  ? 289 TYR E CA  1 
ATOM   16491 C C   . TYR E 1 289 ? 58.152  85.171  24.241  1.00 45.78  ? 289 TYR E C   1 
ATOM   16492 O O   . TYR E 1 289 ? 58.427  85.892  23.293  1.00 43.46  ? 289 TYR E O   1 
ATOM   16493 C CB  . TYR E 1 289 ? 58.372  82.763  23.703  1.00 44.45  ? 289 TYR E CB  1 
ATOM   16494 C CG  . TYR E 1 289 ? 58.330  82.943  22.191  1.00 49.70  ? 289 TYR E CG  1 
ATOM   16495 C CD1 . TYR E 1 289 ? 57.292  83.626  21.569  1.00 57.20  ? 289 TYR E CD1 1 
ATOM   16496 C CD2 . TYR E 1 289 ? 59.311  82.389  21.379  1.00 51.86  ? 289 TYR E CD2 1 
ATOM   16497 C CE1 . TYR E 1 289 ? 57.240  83.766  20.192  1.00 59.82  ? 289 TYR E CE1 1 
ATOM   16498 C CE2 . TYR E 1 289 ? 59.264  82.504  20.000  1.00 55.86  ? 289 TYR E CE2 1 
ATOM   16499 C CZ  . TYR E 1 289 ? 58.219  83.186  19.404  1.00 61.32  ? 289 TYR E CZ  1 
ATOM   16500 O OH  . TYR E 1 289 ? 58.194  83.306  18.049  1.00 56.74  ? 289 TYR E OH  1 
ATOM   16501 N N   . LYS E 1 290 ? 57.099  85.391  25.028  1.00 49.10  ? 290 LYS E N   1 
ATOM   16502 C CA  . LYS E 1 290 ? 56.281  86.580  24.872  1.00 50.23  ? 290 LYS E CA  1 
ATOM   16503 C C   . LYS E 1 290 ? 57.090  87.781  25.328  1.00 48.04  ? 290 LYS E C   1 
ATOM   16504 O O   . LYS E 1 290 ? 57.118  88.795  24.636  1.00 43.51  ? 290 LYS E O   1 
ATOM   16505 C CB  . LYS E 1 290 ? 54.986  86.545  25.689  1.00 51.04  ? 290 LYS E CB  1 
ATOM   16506 C CG  . LYS E 1 290 ? 53.974  87.597  25.281  1.00 53.10  ? 290 LYS E CG  1 
ATOM   16507 C CD  . LYS E 1 290 ? 52.663  87.528  26.051  1.00 57.18  ? 290 LYS E CD  1 
ATOM   16508 C CE  . LYS E 1 290 ? 51.712  88.619  25.676  1.00 61.57  ? 290 LYS E CE  1 
ATOM   16509 N NZ  . LYS E 1 290 ? 50.650  88.706  26.681  1.00 61.91  ? 290 LYS E NZ  1 
ATOM   16510 N N   . LYS E 1 291 ? 57.772  87.611  26.470  1.00 48.66  ? 291 LYS E N   1 
ATOM   16511 C CA  . LYS E 1 291 ? 58.420  88.708  27.179  1.00 48.98  ? 291 LYS E CA  1 
ATOM   16512 C C   . LYS E 1 291 ? 59.616  89.261  26.396  1.00 48.49  ? 291 LYS E C   1 
ATOM   16513 O O   . LYS E 1 291 ? 59.842  90.470  26.390  1.00 48.97  ? 291 LYS E O   1 
ATOM   16514 C CB  . LYS E 1 291 ? 58.750  88.218  28.592  1.00 45.17  ? 291 LYS E CB  1 
ATOM   16515 C CG  . LYS E 1 291 ? 59.498  89.209  29.433  1.00 48.02  ? 291 LYS E CG  1 
ATOM   16516 C CD  . LYS E 1 291 ? 59.746  88.747  30.861  1.00 54.07  ? 291 LYS E CD  1 
ATOM   16517 C CE  . LYS E 1 291 ? 60.728  89.638  31.565  1.00 58.20  ? 291 LYS E CE  1 
ATOM   16518 N NZ  . LYS E 1 291 ? 60.354  91.054  31.508  1.00 57.98  ? 291 LYS E NZ  1 
ATOM   16519 N N   . PHE E 1 292 ? 60.357  88.383  25.708  1.00 48.91  ? 292 PHE E N   1 
ATOM   16520 C CA  . PHE E 1 292 ? 61.545  88.785  24.968  1.00 46.35  ? 292 PHE E CA  1 
ATOM   16521 C C   . PHE E 1 292 ? 61.264  88.897  23.475  1.00 44.23  ? 292 PHE E C   1 
ATOM   16522 O O   . PHE E 1 292 ? 62.197  89.080  22.700  1.00 42.50  ? 292 PHE E O   1 
ATOM   16523 C CB  . PHE E 1 292 ? 62.661  87.789  25.295  1.00 45.01  ? 292 PHE E CB  1 
ATOM   16524 C CG  . PHE E 1 292 ? 62.986  87.885  26.776  1.00 45.42  ? 292 PHE E CG  1 
ATOM   16525 C CD1 . PHE E 1 292 ? 63.523  89.051  27.305  1.00 41.24  ? 292 PHE E CD1 1 
ATOM   16526 C CD2 . PHE E 1 292 ? 62.691  86.843  27.645  1.00 43.38  ? 292 PHE E CD2 1 
ATOM   16527 C CE1 . PHE E 1 292 ? 63.782  89.151  28.660  1.00 40.93  ? 292 PHE E CE1 1 
ATOM   16528 C CE2 . PHE E 1 292 ? 62.933  86.959  29.004  1.00 40.51  ? 292 PHE E CE2 1 
ATOM   16529 C CZ  . PHE E 1 292 ? 63.487  88.109  29.506  1.00 41.01  ? 292 PHE E CZ  1 
ATOM   16530 N N   . GLY E 1 293 ? 59.989  88.804  23.074  1.00 47.19  ? 293 GLY E N   1 
ATOM   16531 C CA  . GLY E 1 293 ? 59.611  88.887  21.663  1.00 47.69  ? 293 GLY E CA  1 
ATOM   16532 C C   . GLY E 1 293 ? 60.354  87.875  20.777  1.00 42.36  ? 293 GLY E C   1 
ATOM   16533 O O   . GLY E 1 293 ? 60.571  88.123  19.598  1.00 40.23  ? 293 GLY E O   1 
ATOM   16534 N N   . GLY E 1 294 ? 60.693  86.724  21.363  1.00 39.92  ? 294 GLY E N   1 
ATOM   16535 C CA  . GLY E 1 294 ? 61.404  85.629  20.725  1.00 41.39  ? 294 GLY E CA  1 
ATOM   16536 C C   . GLY E 1 294 ? 62.246  84.876  21.764  1.00 42.63  ? 294 GLY E C   1 
ATOM   16537 O O   . GLY E 1 294 ? 62.083  85.062  22.975  1.00 37.87  ? 294 GLY E O   1 
ATOM   16538 N N   . VAL E 1 295 ? 63.198  84.079  21.273  1.00 42.29  ? 295 VAL E N   1 
ATOM   16539 C CA  . VAL E 1 295 ? 64.139  83.365  22.118  1.00 43.67  ? 295 VAL E CA  1 
ATOM   16540 C C   . VAL E 1 295 ? 65.027  84.377  22.840  1.00 42.92  ? 295 VAL E C   1 
ATOM   16541 O O   . VAL E 1 295 ? 65.763  85.110  22.189  1.00 39.94  ? 295 VAL E O   1 
ATOM   16542 C CB  . VAL E 1 295 ? 65.008  82.385  21.301  1.00 41.81  ? 295 VAL E CB  1 
ATOM   16543 C CG1 . VAL E 1 295 ? 66.031  81.698  22.194  1.00 39.05  ? 295 VAL E CG1 1 
ATOM   16544 C CG2 . VAL E 1 295 ? 64.173  81.345  20.550  1.00 41.58  ? 295 VAL E CG2 1 
ATOM   16545 N N   . PRO E 1 296 ? 65.046  84.421  24.195  1.00 43.38  ? 296 PRO E N   1 
ATOM   16546 C CA  . PRO E 1 296 ? 66.023  85.249  24.901  1.00 48.02  ? 296 PRO E CA  1 
ATOM   16547 C C   . PRO E 1 296 ? 67.465  84.821  24.611  1.00 52.20  ? 296 PRO E C   1 
ATOM   16548 O O   . PRO E 1 296 ? 67.733  83.689  24.194  1.00 52.97  ? 296 PRO E O   1 
ATOM   16549 C CB  . PRO E 1 296 ? 65.673  85.107  26.396  1.00 44.56  ? 296 PRO E CB  1 
ATOM   16550 C CG  . PRO E 1 296 ? 64.804  83.878  26.478  1.00 42.42  ? 296 PRO E CG  1 
ATOM   16551 C CD  . PRO E 1 296 ? 64.181  83.662  25.110  1.00 41.75  ? 296 PRO E CD  1 
ATOM   16552 N N   . THR E 1 297 ? 68.388  85.762  24.828  1.00 51.73  ? 297 THR E N   1 
ATOM   16553 C CA  . THR E 1 297 ? 69.811  85.487  24.795  1.00 52.67  ? 297 THR E CA  1 
ATOM   16554 C C   . THR E 1 297 ? 70.208  84.908  26.143  1.00 52.93  ? 297 THR E C   1 
ATOM   16555 O O   . THR E 1 297 ? 69.466  85.019  27.115  1.00 54.34  ? 297 THR E O   1 
ATOM   16556 C CB  . THR E 1 297 ? 70.594  86.770  24.505  1.00 53.84  ? 297 THR E CB  1 
ATOM   16557 O OG1 . THR E 1 297 ? 70.297  87.611  25.625  1.00 43.59  ? 297 THR E OG1 1 
ATOM   16558 C CG2 . THR E 1 297 ? 70.253  87.351  23.138  1.00 48.16  ? 297 THR E CG2 1 
ATOM   16559 N N   . LYS E 1 298 ? 71.392  84.297  26.172  1.00 55.99  ? 298 LYS E N   1 
ATOM   16560 C CA  . LYS E 1 298 ? 72.009  83.841  27.405  1.00 60.31  ? 298 LYS E CA  1 
ATOM   16561 C C   . LYS E 1 298 ? 71.778  84.875  28.506  1.00 58.86  ? 298 LYS E C   1 
ATOM   16562 O O   . LYS E 1 298 ? 71.293  84.541  29.584  1.00 55.76  ? 298 LYS E O   1 
ATOM   16563 C CB  . LYS E 1 298 ? 73.499  83.642  27.113  1.00 67.44  ? 298 LYS E CB  1 
ATOM   16564 C CG  . LYS E 1 298 ? 74.132  82.356  27.605  1.00 72.80  ? 298 LYS E CG  1 
ATOM   16565 C CD  . LYS E 1 298 ? 74.734  81.599  26.420  1.00 83.64  ? 298 LYS E CD  1 
ATOM   16566 C CE  . LYS E 1 298 ? 75.631  80.481  26.818  1.00 92.13  ? 298 LYS E CE  1 
ATOM   16567 N NZ  . LYS E 1 298 ? 76.898  80.969  27.369  1.00 98.88  ? 298 LYS E NZ  1 
ATOM   16568 N N   . GLU E 1 299 ? 72.100  86.138  28.201  1.00 61.97  ? 299 GLU E N   1 
ATOM   16569 C CA  . GLU E 1 299 ? 72.166  87.194  29.204  1.00 61.41  ? 299 GLU E CA  1 
ATOM   16570 C C   . GLU E 1 299 ? 70.767  87.566  29.707  1.00 52.51  ? 299 GLU E C   1 
ATOM   16571 O O   . GLU E 1 299 ? 70.573  87.726  30.912  1.00 52.23  ? 299 GLU E O   1 
ATOM   16572 C CB  . GLU E 1 299 ? 73.023  88.342  28.661  1.00 72.27  ? 299 GLU E CB  1 
ATOM   16573 C CG  . GLU E 1 299 ? 72.467  88.984  27.390  1.00 90.75  ? 299 GLU E CG  1 
ATOM   16574 C CD  . GLU E 1 299 ? 73.447  89.180  26.237  1.00 96.48  ? 299 GLU E CD  1 
ATOM   16575 O OE1 . GLU E 1 299 ? 74.304  88.278  25.995  1.00 84.23  ? 299 GLU E OE1 1 
ATOM   16576 O OE2 . GLU E 1 299 ? 73.297  90.224  25.549  1.00 83.63  ? 299 GLU E OE2 1 
ATOM   16577 N N   . GLN E 1 300 ? 69.780  87.677  28.811  1.00 52.48  ? 300 GLN E N   1 
ATOM   16578 C CA  . GLN E 1 300 ? 68.411  87.972  29.222  1.00 54.24  ? 300 GLN E CA  1 
ATOM   16579 C C   . GLN E 1 300 ? 67.870  86.872  30.141  1.00 52.29  ? 300 GLN E C   1 
ATOM   16580 O O   . GLN E 1 300 ? 67.228  87.157  31.160  1.00 49.31  ? 300 GLN E O   1 
ATOM   16581 C CB  . GLN E 1 300 ? 67.502  88.147  28.007  1.00 54.12  ? 300 GLN E CB  1 
ATOM   16582 C CG  . GLN E 1 300 ? 67.879  89.335  27.135  1.00 56.24  ? 300 GLN E CG  1 
ATOM   16583 C CD  . GLN E 1 300 ? 67.102  89.397  25.837  1.00 56.30  ? 300 GLN E CD  1 
ATOM   16584 O OE1 . GLN E 1 300 ? 67.051  88.429  25.069  1.00 55.83  ? 300 GLN E OE1 1 
ATOM   16585 N NE2 . GLN E 1 300 ? 66.488  90.546  25.576  1.00 54.43  ? 300 GLN E NE2 1 
ATOM   16586 N N   . LEU E 1 301 ? 68.149  85.615  29.778  1.00 47.80  ? 301 LEU E N   1 
ATOM   16587 C CA  . LEU E 1 301 ? 67.650  84.478  30.530  1.00 49.68  ? 301 LEU E CA  1 
ATOM   16588 C C   . LEU E 1 301 ? 68.243  84.438  31.940  1.00 54.71  ? 301 LEU E C   1 
ATOM   16589 O O   . LEU E 1 301 ? 67.500  84.225  32.899  1.00 55.37  ? 301 LEU E O   1 
ATOM   16590 C CB  . LEU E 1 301 ? 67.935  83.194  29.758  1.00 45.99  ? 301 LEU E CB  1 
ATOM   16591 C CG  . LEU E 1 301 ? 67.340  81.931  30.378  1.00 44.89  ? 301 LEU E CG  1 
ATOM   16592 C CD1 . LEU E 1 301 ? 65.834  82.078  30.542  1.00 42.94  ? 301 LEU E CD1 1 
ATOM   16593 C CD2 . LEU E 1 301 ? 67.696  80.704  29.549  1.00 46.04  ? 301 LEU E CD2 1 
ATOM   16594 N N   . GLU E 1 302 ? 69.574  84.613  32.051  1.00 59.26  ? 302 GLU E N   1 
ATOM   16595 C CA  . GLU E 1 302 ? 70.282  84.678  33.329  1.00 54.00  ? 302 GLU E CA  1 
ATOM   16596 C C   . GLU E 1 302 ? 69.724  85.764  34.243  1.00 49.64  ? 302 GLU E C   1 
ATOM   16597 O O   . GLU E 1 302 ? 69.564  85.530  35.429  1.00 52.94  ? 302 GLU E O   1 
ATOM   16598 C CB  . GLU E 1 302 ? 71.759  85.046  33.203  1.00 58.53  ? 302 GLU E CB  1 
ATOM   16599 C CG  . GLU E 1 302 ? 72.680  83.850  32.994  1.00 63.02  ? 302 GLU E CG  1 
ATOM   16600 C CD  . GLU E 1 302 ? 74.103  84.319  32.809  1.00 61.12  ? 302 GLU E CD  1 
ATOM   16601 O OE1 . GLU E 1 302 ? 74.664  84.774  33.830  1.00 58.96  ? 302 GLU E OE1 1 
ATOM   16602 O OE2 . GLU E 1 302 ? 74.598  84.292  31.658  1.00 47.09  ? 302 GLU E OE2 1 
ATOM   16603 N N   . ARG E 1 303 ? 69.509  86.969  33.713  1.00 50.61  ? 303 ARG E N   1 
ATOM   16604 C CA  . ARG E 1 303 ? 68.976  88.061  34.510  1.00 57.63  ? 303 ARG E CA  1 
ATOM   16605 C C   . ARG E 1 303 ? 67.603  87.665  35.049  1.00 53.71  ? 303 ARG E C   1 
ATOM   16606 O O   . ARG E 1 303 ? 67.333  87.839  36.248  1.00 49.24  ? 303 ARG E O   1 
ATOM   16607 C CB  . ARG E 1 303 ? 68.873  89.364  33.706  1.00 67.77  ? 303 ARG E CB  1 
ATOM   16608 C CG  . ARG E 1 303 ? 68.411  90.587  34.493  1.00 73.76  ? 303 ARG E CG  1 
ATOM   16609 C CD  . ARG E 1 303 ? 67.757  91.654  33.625  1.00 81.23  ? 303 ARG E CD  1 
ATOM   16610 N NE  . ARG E 1 303 ? 66.623  90.999  32.959  1.00 102.84 ? 303 ARG E NE  1 
ATOM   16611 C CZ  . ARG E 1 303 ? 66.465  90.710  31.662  1.00 95.31  ? 303 ARG E CZ  1 
ATOM   16612 N NH1 . ARG E 1 303 ? 67.103  91.375  30.708  1.00 89.40  ? 303 ARG E NH1 1 
ATOM   16613 N NH2 . ARG E 1 303 ? 65.592  89.773  31.335  1.00 90.73  ? 303 ARG E NH2 1 
ATOM   16614 N N   . PHE E 1 304 ? 66.759  87.126  34.151  1.00 51.44  ? 304 PHE E N   1 
ATOM   16615 C CA  . PHE E 1 304 ? 65.390  86.747  34.496  1.00 50.78  ? 304 PHE E CA  1 
ATOM   16616 C C   . PHE E 1 304 ? 65.366  85.628  35.539  1.00 47.43  ? 304 PHE E C   1 
ATOM   16617 O O   . PHE E 1 304 ? 64.487  85.622  36.394  1.00 51.48  ? 304 PHE E O   1 
ATOM   16618 C CB  . PHE E 1 304 ? 64.546  86.300  33.298  1.00 52.37  ? 304 PHE E CB  1 
ATOM   16619 C CG  . PHE E 1 304 ? 63.131  85.918  33.709  1.00 51.96  ? 304 PHE E CG  1 
ATOM   16620 C CD1 . PHE E 1 304 ? 62.142  86.886  33.824  1.00 50.99  ? 304 PHE E CD1 1 
ATOM   16621 C CD2 . PHE E 1 304 ? 62.804  84.599  34.014  1.00 47.13  ? 304 PHE E CD2 1 
ATOM   16622 C CE1 . PHE E 1 304 ? 60.864  86.541  34.231  1.00 49.63  ? 304 PHE E CE1 1 
ATOM   16623 C CE2 . PHE E 1 304 ? 61.521  84.263  34.404  1.00 46.86  ? 304 PHE E CE2 1 
ATOM   16624 C CZ  . PHE E 1 304 ? 60.559  85.235  34.530  1.00 45.40  ? 304 PHE E CZ  1 
ATOM   16625 N N   . ALA E 1 305 ? 66.312  84.681  35.452  1.00 49.62  ? 305 ALA E N   1 
ATOM   16626 C CA  . ALA E 1 305 ? 66.442  83.588  36.410  1.00 49.70  ? 305 ALA E CA  1 
ATOM   16627 C C   . ALA E 1 305 ? 66.854  84.117  37.781  1.00 53.67  ? 305 ALA E C   1 
ATOM   16628 O O   . ALA E 1 305 ? 66.294  83.699  38.795  1.00 57.99  ? 305 ALA E O   1 
ATOM   16629 C CB  . ALA E 1 305 ? 67.451  82.561  35.929  1.00 47.13  ? 305 ALA E CB  1 
ATOM   16630 N N   . TRP E 1 306 ? 67.864  85.000  37.804  1.00 53.26  ? 306 TRP E N   1 
ATOM   16631 C CA  . TRP E 1 306 ? 68.371  85.555  39.050  1.00 51.85  ? 306 TRP E CA  1 
ATOM   16632 C C   . TRP E 1 306 ? 67.296  86.404  39.716  1.00 46.78  ? 306 TRP E C   1 
ATOM   16633 O O   . TRP E 1 306 ? 67.095  86.274  40.922  1.00 42.99  ? 306 TRP E O   1 
ATOM   16634 C CB  . TRP E 1 306 ? 69.641  86.383  38.815  1.00 57.81  ? 306 TRP E CB  1 
ATOM   16635 C CG  . TRP E 1 306 ? 70.933  85.612  38.870  1.00 53.29  ? 306 TRP E CG  1 
ATOM   16636 C CD1 . TRP E 1 306 ? 71.748  85.297  37.821  1.00 50.70  ? 306 TRP E CD1 1 
ATOM   16637 C CD2 . TRP E 1 306 ? 71.559  85.069  40.049  1.00 55.83  ? 306 TRP E CD2 1 
ATOM   16638 N NE1 . TRP E 1 306 ? 72.842  84.602  38.264  1.00 52.35  ? 306 TRP E NE1 1 
ATOM   16639 C CE2 . TRP E 1 306 ? 72.755  84.445  39.625  1.00 60.16  ? 306 TRP E CE2 1 
ATOM   16640 C CE3 . TRP E 1 306 ? 71.232  85.046  41.409  1.00 65.08  ? 306 TRP E CE3 1 
ATOM   16641 C CZ2 . TRP E 1 306 ? 73.618  83.807  40.518  1.00 66.20  ? 306 TRP E CZ2 1 
ATOM   16642 C CZ3 . TRP E 1 306 ? 72.092  84.420  42.290  1.00 69.35  ? 306 TRP E CZ3 1 
ATOM   16643 C CH2 . TRP E 1 306 ? 73.270  83.814  41.850  1.00 65.94  ? 306 TRP E CH2 1 
ATOM   16644 N N   . ASP E 1 307 ? 66.627  87.250  38.911  1.00 53.10  ? 307 ASP E N   1 
ATOM   16645 C CA  . ASP E 1 307 ? 65.430  87.982  39.316  1.00 60.00  ? 307 ASP E CA  1 
ATOM   16646 C C   . ASP E 1 307 ? 64.390  87.045  39.936  1.00 63.85  ? 307 ASP E C   1 
ATOM   16647 O O   . ASP E 1 307 ? 63.864  87.342  41.008  1.00 72.68  ? 307 ASP E O   1 
ATOM   16648 C CB  . ASP E 1 307 ? 64.806  88.734  38.149  1.00 58.81  ? 307 ASP E CB  1 
ATOM   16649 C CG  . ASP E 1 307 ? 65.373  90.121  37.890  1.00 64.78  ? 307 ASP E CG  1 
ATOM   16650 O OD1 . ASP E 1 307 ? 65.828  90.749  38.873  1.00 64.17  ? 307 ASP E OD1 1 
ATOM   16651 O OD2 . ASP E 1 307 ? 65.365  90.557  36.708  1.00 59.12  ? 307 ASP E OD2 1 
ATOM   16652 N N   . THR E 1 308 ? 64.092  85.931  39.246  1.00 56.93  ? 308 THR E N   1 
ATOM   16653 C CA  . THR E 1 308 ? 63.183  84.912  39.752  1.00 54.34  ? 308 THR E CA  1 
ATOM   16654 C C   . THR E 1 308 ? 63.638  84.451  41.138  1.00 49.47  ? 308 THR E C   1 
ATOM   16655 O O   . THR E 1 308 ? 62.895  84.592  42.100  1.00 57.74  ? 308 THR E O   1 
ATOM   16656 C CB  . THR E 1 308 ? 63.092  83.755  38.750  1.00 53.11  ? 308 THR E CB  1 
ATOM   16657 O OG1 . THR E 1 308 ? 62.232  84.171  37.691  1.00 44.05  ? 308 THR E OG1 1 
ATOM   16658 C CG2 . THR E 1 308 ? 62.512  82.491  39.361  1.00 56.21  ? 308 THR E CG2 1 
ATOM   16659 N N   . LEU E 1 309 ? 64.865  83.922  41.234  1.00 49.96  ? 309 LEU E N   1 
ATOM   16660 C CA  . LEU E 1 309 ? 65.398  83.376  42.474  1.00 52.59  ? 309 LEU E CA  1 
ATOM   16661 C C   . LEU E 1 309 ? 65.479  84.433  43.581  1.00 52.02  ? 309 LEU E C   1 
ATOM   16662 O O   . LEU E 1 309 ? 65.371  84.076  44.748  1.00 41.79  ? 309 LEU E O   1 
ATOM   16663 C CB  . LEU E 1 309 ? 66.762  82.724  42.229  1.00 55.46  ? 309 LEU E CB  1 
ATOM   16664 C CG  . LEU E 1 309 ? 66.765  81.412  41.429  1.00 59.62  ? 309 LEU E CG  1 
ATOM   16665 C CD1 . LEU E 1 309 ? 68.183  80.954  41.160  1.00 62.93  ? 309 LEU E CD1 1 
ATOM   16666 C CD2 . LEU E 1 309 ? 66.018  80.267  42.098  1.00 62.45  ? 309 LEU E CD2 1 
ATOM   16667 N N   . ASN E 1 310 ? 65.690  85.713  43.225  1.00 59.63  ? 310 ASN E N   1 
ATOM   16668 C CA  . ASN E 1 310 ? 65.819  86.799  44.193  1.00 61.39  ? 310 ASN E CA  1 
ATOM   16669 C C   . ASN E 1 310 ? 64.472  87.392  44.613  1.00 68.80  ? 310 ASN E C   1 
ATOM   16670 O O   . ASN E 1 310 ? 64.452  88.352  45.380  1.00 76.24  ? 310 ASN E O   1 
ATOM   16671 C CB  . ASN E 1 310 ? 66.592  87.991  43.640  1.00 62.29  ? 310 ASN E CB  1 
ATOM   16672 C CG  . ASN E 1 310 ? 68.075  87.754  43.483  1.00 59.53  ? 310 ASN E CG  1 
ATOM   16673 O OD1 . ASN E 1 310 ? 68.652  86.810  44.040  1.00 53.72  ? 310 ASN E OD1 1 
ATOM   16674 N ND2 . ASN E 1 310 ? 68.708  88.644  42.737  1.00 59.59  ? 310 ASN E ND2 1 
ATOM   16675 N N   . SER E 1 311 ? 63.356  86.889  44.064  1.00 68.68  ? 311 SER E N   1 
ATOM   16676 C CA  . SER E 1 311 ? 62.036  87.216  44.584  1.00 61.50  ? 311 SER E CA  1 
ATOM   16677 C C   . SER E 1 311 ? 61.413  85.979  45.238  1.00 57.66  ? 311 SER E C   1 
ATOM   16678 O O   . SER E 1 311 ? 60.215  85.949  45.507  1.00 53.71  ? 311 SER E O   1 
ATOM   16679 C CB  . SER E 1 311 ? 61.159  87.825  43.514  1.00 63.64  ? 311 SER E CB  1 
ATOM   16680 O OG  . SER E 1 311 ? 60.843  86.899  42.482  1.00 72.99  ? 311 SER E OG  1 
ATOM   16681 N N   . GLY E 1 312 ? 62.247  84.965  45.519  1.00 57.95  ? 312 GLY E N   1 
ATOM   16682 C CA  . GLY E 1 312 ? 61.857  83.793  46.296  1.00 58.07  ? 312 GLY E CA  1 
ATOM   16683 C C   . GLY E 1 312 ? 61.111  82.738  45.477  1.00 62.81  ? 312 GLY E C   1 
ATOM   16684 O O   . GLY E 1 312 ? 60.578  81.786  46.025  1.00 59.11  ? 312 GLY E O   1 
ATOM   16685 N N   . GLN E 1 313 ? 61.080  82.891  44.153  1.00 75.11  ? 313 GLN E N   1 
ATOM   16686 C CA  . GLN E 1 313 ? 60.443  81.913  43.288  1.00 71.28  ? 313 GLN E CA  1 
ATOM   16687 C C   . GLN E 1 313 ? 61.374  80.728  43.041  1.00 63.11  ? 313 GLN E C   1 
ATOM   16688 O O   . GLN E 1 313 ? 62.534  80.726  43.462  1.00 64.63  ? 313 GLN E O   1 
ATOM   16689 C CB  . GLN E 1 313 ? 60.056  82.616  41.988  1.00 76.66  ? 313 GLN E CB  1 
ATOM   16690 C CG  . GLN E 1 313 ? 58.955  83.654  42.167  1.00 79.59  ? 313 GLN E CG  1 
ATOM   16691 C CD  . GLN E 1 313 ? 57.672  83.010  42.642  1.00 90.13  ? 313 GLN E CD  1 
ATOM   16692 O OE1 . GLN E 1 313 ? 56.934  82.390  41.862  1.00 88.13  ? 313 GLN E OE1 1 
ATOM   16693 N NE2 . GLN E 1 313 ? 57.427  83.111  43.942  1.00 91.82  ? 313 GLN E NE2 1 
ATOM   16694 N N   . VAL E 1 314 ? 60.816  79.703  42.388  1.00 60.02  ? 314 VAL E N   1 
ATOM   16695 C CA  . VAL E 1 314 ? 61.590  78.595  41.838  1.00 60.08  ? 314 VAL E CA  1 
ATOM   16696 C C   . VAL E 1 314 ? 61.487  78.658  40.317  1.00 49.25  ? 314 VAL E C   1 
ATOM   16697 O O   . VAL E 1 314 ? 60.573  79.257  39.748  1.00 41.75  ? 314 VAL E O   1 
ATOM   16698 C CB  . VAL E 1 314 ? 61.199  77.174  42.300  1.00 60.46  ? 314 VAL E CB  1 
ATOM   16699 C CG1 . VAL E 1 314 ? 61.886  76.791  43.610  1.00 58.51  ? 314 VAL E CG1 1 
ATOM   16700 C CG2 . VAL E 1 314 ? 59.679  76.986  42.351  1.00 59.74  ? 314 VAL E CG2 1 
ATOM   16701 N N   . ILE E 1 315 ? 62.444  78.002  39.675  1.00 41.07  ? 315 ILE E N   1 
ATOM   16702 C CA  . ILE E 1 315 ? 62.382  77.823  38.250  1.00 40.01  ? 315 ILE E CA  1 
ATOM   16703 C C   . ILE E 1 315 ? 61.665  76.511  37.968  1.00 39.95  ? 315 ILE E C   1 
ATOM   16704 O O   . ILE E 1 315 ? 62.064  75.479  38.494  1.00 36.36  ? 315 ILE E O   1 
ATOM   16705 C CB  . ILE E 1 315 ? 63.793  77.914  37.678  1.00 42.59  ? 315 ILE E CB  1 
ATOM   16706 C CG1 . ILE E 1 315 ? 64.179  79.373  37.673  1.00 41.99  ? 315 ILE E CG1 1 
ATOM   16707 C CG2 . ILE E 1 315 ? 63.865  77.281  36.288  1.00 46.54  ? 315 ILE E CG2 1 
ATOM   16708 C CD1 . ILE E 1 315 ? 65.643  79.604  37.426  1.00 45.02  ? 315 ILE E CD1 1 
ATOM   16709 N N   . PRO E 1 316 ? 60.536  76.531  37.211  1.00 42.54  ? 316 PRO E N   1 
ATOM   16710 C CA  . PRO E 1 316 ? 59.719  75.331  37.011  1.00 38.93  ? 316 PRO E CA  1 
ATOM   16711 C C   . PRO E 1 316 ? 60.514  74.309  36.214  1.00 36.27  ? 316 PRO E C   1 
ATOM   16712 O O   . PRO E 1 316 ? 61.262  74.676  35.313  1.00 34.58  ? 316 PRO E O   1 
ATOM   16713 C CB  . PRO E 1 316 ? 58.470  75.833  36.260  1.00 42.10  ? 316 PRO E CB  1 
ATOM   16714 C CG  . PRO E 1 316 ? 58.489  77.337  36.439  1.00 41.90  ? 316 PRO E CG  1 
ATOM   16715 C CD  . PRO E 1 316 ? 59.950  77.716  36.557  1.00 40.29  ? 316 PRO E CD  1 
ATOM   16716 N N   . GLY E 1 317 ? 60.365  73.036  36.581  1.00 35.49  ? 317 GLY E N   1 
ATOM   16717 C CA  . GLY E 1 317 ? 61.051  71.956  35.894  1.00 34.48  ? 317 GLY E CA  1 
ATOM   16718 C C   . GLY E 1 317 ? 62.448  71.677  36.455  1.00 34.67  ? 317 GLY E C   1 
ATOM   16719 O O   . GLY E 1 317 ? 63.058  70.662  36.113  1.00 32.86  ? 317 GLY E O   1 
ATOM   16720 N N   . TYR E 1 318 ? 62.941  72.541  37.350  1.00 35.07  ? 318 TYR E N   1 
ATOM   16721 C CA  . TYR E 1 318 ? 64.291  72.406  37.875  1.00 38.42  ? 318 TYR E CA  1 
ATOM   16722 C C   . TYR E 1 318 ? 64.309  72.341  39.404  1.00 45.55  ? 318 TYR E C   1 
ATOM   16723 O O   . TYR E 1 318 ? 63.536  72.997  40.106  1.00 44.48  ? 318 TYR E O   1 
ATOM   16724 C CB  . TYR E 1 318 ? 65.095  73.601  37.362  1.00 37.81  ? 318 TYR E CB  1 
ATOM   16725 C CG  . TYR E 1 318 ? 65.576  73.501  35.923  1.00 41.28  ? 318 TYR E CG  1 
ATOM   16726 C CD1 . TYR E 1 318 ? 64.722  73.750  34.859  1.00 37.85  ? 318 TYR E CD1 1 
ATOM   16727 C CD2 . TYR E 1 318 ? 66.903  73.197  35.631  1.00 42.92  ? 318 TYR E CD2 1 
ATOM   16728 C CE1 . TYR E 1 318 ? 65.168  73.688  33.548  1.00 41.93  ? 318 TYR E CE1 1 
ATOM   16729 C CE2 . TYR E 1 318 ? 67.359  73.123  34.325  1.00 41.86  ? 318 TYR E CE2 1 
ATOM   16730 C CZ  . TYR E 1 318 ? 66.495  73.381  33.277  1.00 43.61  ? 318 TYR E CZ  1 
ATOM   16731 O OH  . TYR E 1 318 ? 66.958  73.327  31.991  1.00 40.35  ? 318 TYR E OH  1 
ATOM   16732 N N   . GLY E 1 319 ? 65.268  71.567  39.917  1.00 54.62  ? 319 GLY E N   1 
ATOM   16733 C CA  . GLY E 1 319 ? 65.699  71.688  41.299  1.00 53.63  ? 319 GLY E CA  1 
ATOM   16734 C C   . GLY E 1 319 ? 64.836  70.856  42.238  1.00 58.72  ? 319 GLY E C   1 
ATOM   16735 O O   . GLY E 1 319 ? 64.480  71.325  43.316  1.00 67.72  ? 319 GLY E O   1 
ATOM   16736 N N   . HIS E 1 320 ? 64.524  69.623  41.831  1.00 55.92  ? 320 HIS E N   1 
ATOM   16737 C CA  . HIS E 1 320 ? 63.755  68.730  42.682  1.00 63.28  ? 320 HIS E CA  1 
ATOM   16738 C C   . HIS E 1 320 ? 64.708  67.935  43.585  1.00 62.92  ? 320 HIS E C   1 
ATOM   16739 O O   . HIS E 1 320 ? 65.867  67.684  43.249  1.00 58.78  ? 320 HIS E O   1 
ATOM   16740 C CB  . HIS E 1 320 ? 62.750  67.959  41.814  1.00 67.16  ? 320 HIS E CB  1 
ATOM   16741 C CG  . HIS E 1 320 ? 61.570  68.776  41.357  1.00 67.09  ? 320 HIS E CG  1 
ATOM   16742 N ND1 . HIS E 1 320 ? 60.313  68.672  41.921  1.00 64.61  ? 320 HIS E ND1 1 
ATOM   16743 C CD2 . HIS E 1 320 ? 61.450  69.699  40.382  1.00 68.83  ? 320 HIS E CD2 1 
ATOM   16744 C CE1 . HIS E 1 320 ? 59.478  69.502  41.303  1.00 61.79  ? 320 HIS E CE1 1 
ATOM   16745 N NE2 . HIS E 1 320 ? 60.145  70.137  40.364  1.00 60.78  ? 320 HIS E NE2 1 
ATOM   16746 N N   . ALA E 1 321 ? 64.195  67.516  44.746  1.00 69.51  ? 321 ALA E N   1 
ATOM   16747 C CA  . ALA E 1 321 ? 65.038  67.138  45.873  1.00 70.59  ? 321 ALA E CA  1 
ATOM   16748 C C   . ALA E 1 321 ? 65.627  65.720  45.759  1.00 72.04  ? 321 ALA E C   1 
ATOM   16749 O O   . ALA E 1 321 ? 66.645  65.458  46.393  1.00 65.37  ? 321 ALA E O   1 
ATOM   16750 C CB  . ALA E 1 321 ? 64.254  67.322  47.167  1.00 68.57  ? 321 ALA E CB  1 
ATOM   16751 N N   . VAL E 1 322 ? 65.023  64.794  44.985  1.00 75.67  ? 322 VAL E N   1 
ATOM   16752 C CA  . VAL E 1 322 ? 65.414  63.384  45.047  1.00 68.09  ? 322 VAL E CA  1 
ATOM   16753 C C   . VAL E 1 322 ? 66.644  63.112  44.168  1.00 60.87  ? 322 VAL E C   1 
ATOM   16754 O O   . VAL E 1 322 ? 67.562  62.425  44.607  1.00 65.25  ? 322 VAL E O   1 
ATOM   16755 C CB  . VAL E 1 322 ? 64.289  62.386  44.714  1.00 78.04  ? 322 VAL E CB  1 
ATOM   16756 C CG1 . VAL E 1 322 ? 64.638  60.988  45.221  1.00 79.86  ? 322 VAL E CG1 1 
ATOM   16757 C CG2 . VAL E 1 322 ? 62.934  62.826  45.264  1.00 81.22  ? 322 VAL E CG2 1 
ATOM   16758 N N   . LEU E 1 323 ? 66.684  63.639  42.936  1.00 49.15  ? 323 LEU E N   1 
ATOM   16759 C CA  . LEU E 1 323 ? 67.814  63.393  42.044  1.00 47.77  ? 323 LEU E CA  1 
ATOM   16760 C C   . LEU E 1 323 ? 68.966  64.351  42.335  1.00 45.22  ? 323 LEU E C   1 
ATOM   16761 O O   . LEU E 1 323 ? 68.760  65.452  42.831  1.00 48.58  ? 323 LEU E O   1 
ATOM   16762 C CB  . LEU E 1 323 ? 67.438  63.543  40.570  1.00 43.28  ? 323 LEU E CB  1 
ATOM   16763 C CG  . LEU E 1 323 ? 66.470  62.519  39.983  1.00 39.04  ? 323 LEU E CG  1 
ATOM   16764 C CD1 . LEU E 1 323 ? 66.663  62.524  38.477  1.00 41.75  ? 323 LEU E CD1 1 
ATOM   16765 C CD2 . LEU E 1 323 ? 66.662  61.138  40.561  1.00 38.81  ? 323 LEU E CD2 1 
ATOM   16766 N N   . ARG E 1 324 ? 70.178  63.952  41.945  1.00 41.36  ? 324 ARG E N   1 
ATOM   16767 C CA  . ARG E 1 324 ? 71.319  64.850  42.026  1.00 46.01  ? 324 ARG E CA  1 
ATOM   16768 C C   . ARG E 1 324 ? 71.999  64.964  40.669  1.00 42.56  ? 324 ARG E C   1 
ATOM   16769 O O   . ARG E 1 324 ? 73.000  65.646  40.535  1.00 41.08  ? 324 ARG E O   1 
ATOM   16770 C CB  . ARG E 1 324 ? 72.231  64.391  43.167  1.00 57.01  ? 324 ARG E CB  1 
ATOM   16771 C CG  . ARG E 1 324 ? 71.585  64.614  44.533  1.00 64.65  ? 324 ARG E CG  1 
ATOM   16772 C CD  . ARG E 1 324 ? 72.453  64.142  45.697  1.00 80.17  ? 324 ARG E CD  1 
ATOM   16773 N NE  . ARG E 1 324 ? 72.830  62.720  45.615  1.00 87.25  ? 324 ARG E NE  1 
ATOM   16774 C CZ  . ARG E 1 324 ? 72.762  61.799  46.587  1.00 74.47  ? 324 ARG E CZ  1 
ATOM   16775 N NH1 . ARG E 1 324 ? 72.411  62.141  47.814  1.00 70.07  ? 324 ARG E NH1 1 
ATOM   16776 N NH2 . ARG E 1 324 ? 73.074  60.538  46.323  1.00 68.63  ? 324 ARG E NH2 1 
ATOM   16777 N N   . VAL E 1 325 ? 71.391  64.346  39.655  1.00 43.66  ? 325 VAL E N   1 
ATOM   16778 C CA  . VAL E 1 325 ? 71.835  64.439  38.278  1.00 42.44  ? 325 VAL E CA  1 
ATOM   16779 C C   . VAL E 1 325 ? 70.623  64.763  37.412  1.00 38.60  ? 325 VAL E C   1 
ATOM   16780 O O   . VAL E 1 325 ? 69.493  64.746  37.883  1.00 37.86  ? 325 VAL E O   1 
ATOM   16781 C CB  . VAL E 1 325 ? 72.490  63.115  37.851  1.00 45.79  ? 325 VAL E CB  1 
ATOM   16782 C CG1 . VAL E 1 325 ? 73.668  62.758  38.756  1.00 45.11  ? 325 VAL E CG1 1 
ATOM   16783 C CG2 . VAL E 1 325 ? 71.484  61.969  37.783  1.00 43.29  ? 325 VAL E CG2 1 
ATOM   16784 N N   . THR E 1 326 ? 70.865  65.077  36.145  1.00 37.94  ? 326 THR E N   1 
ATOM   16785 C CA  . THR E 1 326 ? 69.780  65.318  35.207  1.00 38.55  ? 326 THR E CA  1 
ATOM   16786 C C   . THR E 1 326 ? 68.920  64.063  35.058  1.00 36.17  ? 326 THR E C   1 
ATOM   16787 O O   . THR E 1 326 ? 69.467  62.973  34.878  1.00 35.53  ? 326 THR E O   1 
ATOM   16788 C CB  . THR E 1 326 ? 70.357  65.711  33.858  1.00 37.20  ? 326 THR E CB  1 
ATOM   16789 O OG1 . THR E 1 326 ? 70.841  67.035  34.050  1.00 40.46  ? 326 THR E OG1 1 
ATOM   16790 C CG2 . THR E 1 326 ? 69.289  65.690  32.785  1.00 39.66  ? 326 THR E CG2 1 
ATOM   16791 N N   . ASP E 1 327 ? 67.586  64.239  35.121  1.00 31.45  ? 327 ASP E N   1 
ATOM   16792 C CA  . ASP E 1 327 ? 66.641  63.140  34.981  1.00 29.37  ? 327 ASP E CA  1 
ATOM   16793 C C   . ASP E 1 327 ? 66.839  62.494  33.611  1.00 30.21  ? 327 ASP E C   1 
ATOM   16794 O O   . ASP E 1 327 ? 66.829  63.175  32.583  1.00 27.82  ? 327 ASP E O   1 
ATOM   16795 C CB  . ASP E 1 327 ? 65.221  63.661  35.127  1.00 29.62  ? 327 ASP E CB  1 
ATOM   16796 C CG  . ASP E 1 327 ? 64.088  62.643  35.109  1.00 32.15  ? 327 ASP E CG  1 
ATOM   16797 O OD1 . ASP E 1 327 ? 64.349  61.427  34.865  1.00 32.69  ? 327 ASP E OD1 1 
ATOM   16798 O OD2 . ASP E 1 327 ? 62.944  63.072  35.393  1.00 36.12  ? 327 ASP E OD2 1 
ATOM   16799 N N   . PRO E 1 328 ? 67.034  61.163  33.520  1.00 31.21  ? 328 PRO E N   1 
ATOM   16800 C CA  . PRO E 1 328 ? 67.203  60.522  32.212  1.00 31.25  ? 328 PRO E CA  1 
ATOM   16801 C C   . PRO E 1 328 ? 65.962  60.604  31.308  1.00 29.38  ? 328 PRO E C   1 
ATOM   16802 O O   . PRO E 1 328 ? 66.081  60.633  30.086  1.00 29.60  ? 328 PRO E O   1 
ATOM   16803 C CB  . PRO E 1 328 ? 67.648  59.068  32.533  1.00 31.85  ? 328 PRO E CB  1 
ATOM   16804 C CG  . PRO E 1 328 ? 67.293  58.856  33.986  1.00 33.79  ? 328 PRO E CG  1 
ATOM   16805 C CD  . PRO E 1 328 ? 67.152  60.233  34.645  1.00 32.08  ? 328 PRO E CD  1 
ATOM   16806 N N   . ARG E 1 329 ? 64.775  60.686  31.912  1.00 27.49  ? 329 ARG E N   1 
ATOM   16807 C CA  . ARG E 1 329 ? 63.552  60.944  31.172  1.00 26.99  ? 329 ARG E CA  1 
ATOM   16808 C C   . ARG E 1 329 ? 63.615  62.291  30.443  1.00 28.36  ? 329 ARG E C   1 
ATOM   16809 O O   . ARG E 1 329 ? 63.037  62.420  29.364  1.00 27.56  ? 329 ARG E O   1 
ATOM   16810 C CB  . ARG E 1 329 ? 62.361  60.892  32.134  1.00 27.04  ? 329 ARG E CB  1 
ATOM   16811 C CG  . ARG E 1 329 ? 62.137  59.506  32.719  1.00 28.13  ? 329 ARG E CG  1 
ATOM   16812 C CD  . ARG E 1 329 ? 61.121  59.428  33.842  1.00 27.16  ? 329 ARG E CD  1 
ATOM   16813 N NE  . ARG E 1 329 ? 61.453  60.400  34.890  1.00 27.92  ? 329 ARG E NE  1 
ATOM   16814 C CZ  . ARG E 1 329 ? 60.593  60.805  35.818  1.00 28.81  ? 329 ARG E CZ  1 
ATOM   16815 N NH1 . ARG E 1 329 ? 59.457  60.168  36.019  1.00 28.89  ? 329 ARG E NH1 1 
ATOM   16816 N NH2 . ARG E 1 329 ? 60.872  61.870  36.539  1.00 30.16  ? 329 ARG E NH2 1 
ATOM   16817 N N   . TYR E 1 330 ? 64.269  63.299  31.043  1.00 29.27  ? 330 TYR E N   1 
ATOM   16818 C CA  . TYR E 1 330 ? 64.515  64.578  30.383  1.00 29.92  ? 330 TYR E CA  1 
ATOM   16819 C C   . TYR E 1 330 ? 65.503  64.393  29.237  1.00 32.53  ? 330 TYR E C   1 
ATOM   16820 O O   . TYR E 1 330 ? 65.333  64.989  28.166  1.00 33.89  ? 330 TYR E O   1 
ATOM   16821 C CB  . TYR E 1 330 ? 65.106  65.629  31.322  1.00 29.28  ? 330 TYR E CB  1 
ATOM   16822 C CG  . TYR E 1 330 ? 65.429  66.987  30.714  1.00 28.88  ? 330 TYR E CG  1 
ATOM   16823 C CD1 . TYR E 1 330 ? 66.675  67.261  30.179  1.00 29.45  ? 330 TYR E CD1 1 
ATOM   16824 C CD2 . TYR E 1 330 ? 64.514  68.031  30.773  1.00 31.14  ? 330 TYR E CD2 1 
ATOM   16825 C CE1 . TYR E 1 330 ? 66.977  68.513  29.675  1.00 30.54  ? 330 TYR E CE1 1 
ATOM   16826 C CE2 . TYR E 1 330 ? 64.799  69.293  30.274  1.00 30.43  ? 330 TYR E CE2 1 
ATOM   16827 C CZ  . TYR E 1 330 ? 66.041  69.531  29.726  1.00 31.76  ? 330 TYR E CZ  1 
ATOM   16828 O OH  . TYR E 1 330 ? 66.306  70.764  29.212  1.00 34.60  ? 330 TYR E OH  1 
ATOM   16829 N N   . VAL E 1 331 ? 66.532  63.570  29.476  1.00 34.00  ? 331 VAL E N   1 
ATOM   16830 C CA  . VAL E 1 331 ? 67.599  63.397  28.499  1.00 37.31  ? 331 VAL E CA  1 
ATOM   16831 C C   . VAL E 1 331 ? 67.008  62.779  27.223  1.00 35.40  ? 331 VAL E C   1 
ATOM   16832 O O   . VAL E 1 331 ? 67.141  63.332  26.124  1.00 32.95  ? 331 VAL E O   1 
ATOM   16833 C CB  . VAL E 1 331 ? 68.749  62.569  29.117  1.00 37.94  ? 331 VAL E CB  1 
ATOM   16834 C CG1 . VAL E 1 331 ? 69.782  62.086  28.092  1.00 34.46  ? 331 VAL E CG1 1 
ATOM   16835 C CG2 . VAL E 1 331 ? 69.435  63.349  30.237  1.00 36.55  ? 331 VAL E CG2 1 
ATOM   16836 N N   . ALA E 1 332 ? 66.293  61.662  27.387  1.00 34.38  ? 332 ALA E N   1 
ATOM   16837 C CA  . ALA E 1 332 ? 65.629  60.999  26.272  1.00 32.96  ? 332 ALA E CA  1 
ATOM   16838 C C   . ALA E 1 332 ? 64.769  61.973  25.464  1.00 29.38  ? 332 ALA E C   1 
ATOM   16839 O O   . ALA E 1 332 ? 64.745  61.879  24.235  1.00 29.28  ? 332 ALA E O   1 
ATOM   16840 C CB  . ALA E 1 332 ? 64.830  59.821  26.758  1.00 31.94  ? 332 ALA E CB  1 
ATOM   16841 N N   . GLN E 1 333 ? 64.088  62.907  26.133  1.00 28.29  ? 333 GLN E N   1 
ATOM   16842 C CA  . GLN E 1 333 ? 63.178  63.811  25.442  1.00 31.11  ? 333 GLN E CA  1 
ATOM   16843 C C   . GLN E 1 333 ? 63.974  64.888  24.716  1.00 32.39  ? 333 GLN E C   1 
ATOM   16844 O O   . GLN E 1 333 ? 63.614  65.275  23.603  1.00 28.76  ? 333 GLN E O   1 
ATOM   16845 C CB  . GLN E 1 333 ? 62.170  64.525  26.338  1.00 31.04  ? 333 GLN E CB  1 
ATOM   16846 C CG  . GLN E 1 333 ? 61.089  63.607  26.894  1.00 36.30  ? 333 GLN E CG  1 
ATOM   16847 C CD  . GLN E 1 333 ? 60.195  64.277  27.928  1.00 38.91  ? 333 GLN E CD  1 
ATOM   16848 O OE1 . GLN E 1 333 ? 60.566  64.485  29.098  1.00 39.65  ? 333 GLN E OE1 1 
ATOM   16849 N NE2 . GLN E 1 333 ? 58.975  64.577  27.502  1.00 35.55  ? 333 GLN E NE2 1 
ATOM   16850 N N   . ARG E 1 334 ? 65.029  65.396  25.369  1.00 33.52  ? 334 ARG E N   1 
ATOM   16851 C CA  . ARG E 1 334 ? 65.962  66.283  24.689  1.00 32.20  ? 334 ARG E CA  1 
ATOM   16852 C C   . ARG E 1 334 ? 66.536  65.586  23.452  1.00 28.35  ? 334 ARG E C   1 
ATOM   16853 O O   . ARG E 1 334 ? 66.649  66.173  22.383  1.00 22.81  ? 334 ARG E O   1 
ATOM   16854 C CB  . ARG E 1 334 ? 67.090  66.699  25.631  1.00 31.04  ? 334 ARG E CB  1 
ATOM   16855 C CG  . ARG E 1 334 ? 68.174  67.535  24.968  1.00 31.33  ? 334 ARG E CG  1 
ATOM   16856 C CD  . ARG E 1 334 ? 69.245  67.914  25.975  1.00 33.68  ? 334 ARG E CD  1 
ATOM   16857 N NE  . ARG E 1 334 ? 70.305  68.726  25.377  1.00 32.23  ? 334 ARG E NE  1 
ATOM   16858 C CZ  . ARG E 1 334 ? 70.128  69.920  24.838  1.00 34.92  ? 334 ARG E CZ  1 
ATOM   16859 N NH1 . ARG E 1 334 ? 68.972  70.558  24.978  1.00 37.52  ? 334 ARG E NH1 1 
ATOM   16860 N NH2 . ARG E 1 334 ? 71.123  70.494  24.183  1.00 33.93  ? 334 ARG E NH2 1 
ATOM   16861 N N   . ASP E 1 335 ? 66.895  64.312  23.583  1.00 29.15  ? 335 ASP E N   1 
ATOM   16862 C CA  . ASP E 1 335 ? 67.455  63.622  22.435  1.00 30.49  ? 335 ASP E CA  1 
ATOM   16863 C C   . ASP E 1 335 ? 66.443  63.617  21.293  1.00 30.93  ? 335 ASP E C   1 
ATOM   16864 O O   . ASP E 1 335 ? 66.824  63.740  20.139  1.00 35.22  ? 335 ASP E O   1 
ATOM   16865 C CB  . ASP E 1 335 ? 67.960  62.239  22.794  1.00 29.82  ? 335 ASP E CB  1 
ATOM   16866 C CG  . ASP E 1 335 ? 68.434  61.420  21.607  1.00 31.78  ? 335 ASP E CG  1 
ATOM   16867 O OD1 . ASP E 1 335 ? 69.500  61.749  21.041  1.00 32.00  ? 335 ASP E OD1 1 
ATOM   16868 O OD2 . ASP E 1 335 ? 67.722  60.465  21.262  1.00 30.86  ? 335 ASP E OD2 1 
ATOM   16869 N N   . PHE E 1 336 ? 65.153  63.504  21.622  1.00 31.87  ? 336 PHE E N   1 
ATOM   16870 C CA  . PHE E 1 336 ? 64.096  63.418  20.626  1.00 29.81  ? 336 PHE E CA  1 
ATOM   16871 C C   . PHE E 1 336 ? 63.945  64.762  19.917  1.00 31.15  ? 336 PHE E C   1 
ATOM   16872 O O   . PHE E 1 336 ? 63.849  64.802  18.695  1.00 32.50  ? 336 PHE E O   1 
ATOM   16873 C CB  . PHE E 1 336 ? 62.792  62.980  21.291  1.00 27.14  ? 336 PHE E CB  1 
ATOM   16874 C CG  . PHE E 1 336 ? 61.633  62.906  20.315  1.00 26.54  ? 336 PHE E CG  1 
ATOM   16875 C CD1 . PHE E 1 336 ? 60.994  64.059  19.874  1.00 25.27  ? 336 PHE E CD1 1 
ATOM   16876 C CD2 . PHE E 1 336 ? 61.185  61.677  19.851  1.00 27.42  ? 336 PHE E CD2 1 
ATOM   16877 C CE1 . PHE E 1 336 ? 59.946  63.977  18.974  1.00 25.11  ? 336 PHE E CE1 1 
ATOM   16878 C CE2 . PHE E 1 336 ? 60.155  61.607  18.939  1.00 26.92  ? 336 PHE E CE2 1 
ATOM   16879 C CZ  . PHE E 1 336 ? 59.543  62.757  18.495  1.00 24.69  ? 336 PHE E CZ  1 
ATOM   16880 N N   . ALA E 1 337 ? 63.935  65.852  20.689  1.00 30.84  ? 337 ALA E N   1 
ATOM   16881 C CA  . ALA E 1 337 ? 63.776  67.179  20.128  1.00 33.89  ? 337 ALA E CA  1 
ATOM   16882 C C   . ALA E 1 337 ? 64.932  67.509  19.187  1.00 37.78  ? 337 ALA E C   1 
ATOM   16883 O O   . ALA E 1 337 ? 64.678  67.942  18.067  1.00 34.46  ? 337 ALA E O   1 
ATOM   16884 C CB  . ALA E 1 337 ? 63.684  68.208  21.224  1.00 35.79  ? 337 ALA E CB  1 
ATOM   16885 N N   . LEU E 1 338 ? 66.180  67.323  19.664  1.00 43.19  ? 338 LEU E N   1 
ATOM   16886 C CA  . LEU E 1 338 ? 67.397  67.652  18.918  1.00 44.12  ? 338 LEU E CA  1 
ATOM   16887 C C   . LEU E 1 338 ? 67.346  66.982  17.548  1.00 41.88  ? 338 LEU E C   1 
ATOM   16888 O O   . LEU E 1 338 ? 67.743  67.577  16.548  1.00 43.48  ? 338 LEU E O   1 
ATOM   16889 C CB  . LEU E 1 338 ? 68.674  67.216  19.646  1.00 41.43  ? 338 LEU E CB  1 
ATOM   16890 C CG  . LEU E 1 338 ? 69.199  68.094  20.792  1.00 38.00  ? 338 LEU E CG  1 
ATOM   16891 C CD1 . LEU E 1 338 ? 70.339  67.357  21.502  1.00 36.51  ? 338 LEU E CD1 1 
ATOM   16892 C CD2 . LEU E 1 338 ? 69.648  69.455  20.299  1.00 34.88  ? 338 LEU E CD2 1 
ATOM   16893 N N   . LYS E 1 339 ? 66.816  65.757  17.555  1.00 36.99  ? 339 LYS E N   1 
ATOM   16894 C CA  . LYS E 1 339 ? 66.696  64.905  16.389  1.00 38.13  ? 339 LYS E CA  1 
ATOM   16895 C C   . LYS E 1 339 ? 65.478  65.274  15.521  1.00 36.06  ? 339 LYS E C   1 
ATOM   16896 O O   . LYS E 1 339 ? 65.569  65.162  14.301  1.00 33.60  ? 339 LYS E O   1 
ATOM   16897 C CB  . LYS E 1 339 ? 66.675  63.494  16.992  1.00 44.39  ? 339 LYS E CB  1 
ATOM   16898 C CG  . LYS E 1 339 ? 67.364  62.388  16.245  1.00 50.79  ? 339 LYS E CG  1 
ATOM   16899 C CD  . LYS E 1 339 ? 67.273  61.049  16.965  1.00 55.96  ? 339 LYS E CD  1 
ATOM   16900 C CE  . LYS E 1 339 ? 68.385  60.783  17.946  1.00 58.41  ? 339 LYS E CE  1 
ATOM   16901 N NZ  . LYS E 1 339 ? 68.273  59.389  18.405  1.00 59.85  ? 339 LYS E NZ  1 
ATOM   16902 N N   . HIS E 1 340 ? 64.343  65.739  16.088  1.00 30.41  ? 340 HIS E N   1 
ATOM   16903 C CA  . HIS E 1 340 ? 63.137  65.837  15.270  1.00 32.38  ? 340 HIS E CA  1 
ATOM   16904 C C   . HIS E 1 340 ? 62.570  67.247  15.123  1.00 29.76  ? 340 HIS E C   1 
ATOM   16905 O O   . HIS E 1 340 ? 61.761  67.480  14.235  1.00 25.21  ? 340 HIS E O   1 
ATOM   16906 C CB  . HIS E 1 340 ? 62.030  64.895  15.760  1.00 35.03  ? 340 HIS E CB  1 
ATOM   16907 C CG  . HIS E 1 340 ? 62.433  63.474  15.720  1.00 37.83  ? 340 HIS E CG  1 
ATOM   16908 N ND1 . HIS E 1 340 ? 62.664  62.834  14.525  1.00 45.99  ? 340 HIS E ND1 1 
ATOM   16909 C CD2 . HIS E 1 340 ? 62.730  62.597  16.676  1.00 43.74  ? 340 HIS E CD2 1 
ATOM   16910 C CE1 . HIS E 1 340 ? 63.040  61.584  14.761  1.00 48.29  ? 340 HIS E CE1 1 
ATOM   16911 N NE2 . HIS E 1 340 ? 63.088  61.417  16.064  1.00 47.67  ? 340 HIS E NE2 1 
ATOM   16912 N N   . LEU E 1 341 ? 62.957  68.182  15.982  1.00 30.65  ? 341 LEU E N   1 
ATOM   16913 C CA  . LEU E 1 341 ? 62.348  69.501  15.947  1.00 31.12  ? 341 LEU E CA  1 
ATOM   16914 C C   . LEU E 1 341 ? 63.327  70.542  16.500  1.00 32.82  ? 341 LEU E C   1 
ATOM   16915 O O   . LEU E 1 341 ? 62.927  71.414  17.269  1.00 31.85  ? 341 LEU E O   1 
ATOM   16916 C CB  . LEU E 1 341 ? 61.012  69.492  16.710  1.00 30.69  ? 341 LEU E CB  1 
ATOM   16917 C CG  . LEU E 1 341 ? 61.058  69.013  18.164  1.00 30.25  ? 341 LEU E CG  1 
ATOM   16918 C CD1 . LEU E 1 341 ? 60.400  70.013  19.058  1.00 32.15  ? 341 LEU E CD1 1 
ATOM   16919 C CD2 . LEU E 1 341 ? 60.403  67.678  18.366  1.00 30.67  ? 341 LEU E CD2 1 
ATOM   16920 N N   . PRO E 1 342 ? 64.603  70.582  16.038  1.00 37.65  ? 342 PRO E N   1 
ATOM   16921 C CA  . PRO E 1 342 ? 65.623  71.415  16.695  1.00 37.98  ? 342 PRO E CA  1 
ATOM   16922 C C   . PRO E 1 342 ? 65.453  72.914  16.488  1.00 37.83  ? 342 PRO E C   1 
ATOM   16923 O O   . PRO E 1 342 ? 66.107  73.689  17.177  1.00 45.65  ? 342 PRO E O   1 
ATOM   16924 C CB  . PRO E 1 342 ? 66.951  70.918  16.095  1.00 38.63  ? 342 PRO E CB  1 
ATOM   16925 C CG  . PRO E 1 342 ? 66.534  70.460  14.689  1.00 40.25  ? 342 PRO E CG  1 
ATOM   16926 C CD  . PRO E 1 342 ? 65.107  69.899  14.825  1.00 37.77  ? 342 PRO E CD  1 
ATOM   16927 N N   . ASP E 1 343 ? 64.585  73.315  15.554  1.00 36.45  ? 343 ASP E N   1 
ATOM   16928 C CA  . ASP E 1 343 ? 64.409  74.726  15.249  1.00 39.69  ? 343 ASP E CA  1 
ATOM   16929 C C   . ASP E 1 343 ? 63.098  75.242  15.827  1.00 38.83  ? 343 ASP E C   1 
ATOM   16930 O O   . ASP E 1 343 ? 62.766  76.426  15.681  1.00 36.72  ? 343 ASP E O   1 
ATOM   16931 C CB  . ASP E 1 343 ? 64.522  75.010  13.758  1.00 43.95  ? 343 ASP E CB  1 
ATOM   16932 C CG  . ASP E 1 343 ? 65.862  74.649  13.114  1.00 50.66  ? 343 ASP E CG  1 
ATOM   16933 O OD1 . ASP E 1 343 ? 66.927  75.091  13.636  1.00 44.48  ? 343 ASP E OD1 1 
ATOM   16934 O OD2 . ASP E 1 343 ? 65.837  73.923  12.079  1.00 53.91  ? 343 ASP E OD2 1 
ATOM   16935 N N   . ASP E 1 344 ? 62.352  74.358  16.493  1.00 37.90  ? 344 ASP E N   1 
ATOM   16936 C CA  . ASP E 1 344 ? 61.169  74.814  17.200  1.00 36.10  ? 344 ASP E CA  1 
ATOM   16937 C C   . ASP E 1 344 ? 61.618  75.805  18.267  1.00 38.93  ? 344 ASP E C   1 
ATOM   16938 O O   . ASP E 1 344 ? 62.539  75.534  19.032  1.00 40.50  ? 344 ASP E O   1 
ATOM   16939 C CB  . ASP E 1 344 ? 60.387  73.656  17.782  1.00 35.58  ? 344 ASP E CB  1 
ATOM   16940 C CG  . ASP E 1 344 ? 59.162  74.025  18.605  1.00 33.93  ? 344 ASP E CG  1 
ATOM   16941 O OD1 . ASP E 1 344 ? 59.335  74.660  19.684  1.00 30.56  ? 344 ASP E OD1 1 
ATOM   16942 O OD2 . ASP E 1 344 ? 58.059  73.638  18.165  1.00 33.96  ? 344 ASP E OD2 1 
ATOM   16943 N N   . GLU E 1 345 ? 60.960  76.962  18.295  1.00 44.10  ? 345 GLU E N   1 
ATOM   16944 C CA  . GLU E 1 345 ? 61.434  78.099  19.062  1.00 44.69  ? 345 GLU E CA  1 
ATOM   16945 C C   . GLU E 1 345 ? 61.281  77.846  20.560  1.00 46.95  ? 345 GLU E C   1 
ATOM   16946 O O   . GLU E 1 345 ? 62.179  78.184  21.334  1.00 50.67  ? 345 GLU E O   1 
ATOM   16947 C CB  . GLU E 1 345 ? 60.709  79.335  18.544  1.00 50.00  ? 345 GLU E CB  1 
ATOM   16948 C CG  . GLU E 1 345 ? 61.112  79.696  17.118  1.00 59.70  ? 345 GLU E CG  1 
ATOM   16949 C CD  . GLU E 1 345 ? 60.995  81.186  16.910  1.00 65.91  ? 345 GLU E CD  1 
ATOM   16950 O OE1 . GLU E 1 345 ? 62.050  81.849  16.879  1.00 71.20  ? 345 GLU E OE1 1 
ATOM   16951 O OE2 . GLU E 1 345 ? 59.852  81.669  16.829  1.00 66.27  ? 345 GLU E OE2 1 
ATOM   16952 N N   . LEU E 1 346 ? 60.166  77.223  20.972  1.00 43.45  ? 346 LEU E N   1 
ATOM   16953 C CA  . LEU E 1 346 ? 59.941  77.001  22.387  1.00 40.64  ? 346 LEU E CA  1 
ATOM   16954 C C   . LEU E 1 346 ? 60.945  75.958  22.856  1.00 41.72  ? 346 LEU E C   1 
ATOM   16955 O O   . LEU E 1 346 ? 61.409  76.038  23.989  1.00 41.80  ? 346 LEU E O   1 
ATOM   16956 C CB  . LEU E 1 346 ? 58.509  76.594  22.708  1.00 36.46  ? 346 LEU E CB  1 
ATOM   16957 C CG  . LEU E 1 346 ? 57.418  77.549  22.224  1.00 36.35  ? 346 LEU E CG  1 
ATOM   16958 C CD1 . LEU E 1 346 ? 56.043  77.037  22.686  1.00 35.32  ? 346 LEU E CD1 1 
ATOM   16959 C CD2 . LEU E 1 346 ? 57.691  78.978  22.689  1.00 36.28  ? 346 LEU E CD2 1 
ATOM   16960 N N   . PHE E 1 347 ? 61.291  75.015  21.965  1.00 41.29  ? 347 PHE E N   1 
ATOM   16961 C CA  . PHE E 1 347 ? 62.378  74.082  22.226  1.00 41.42  ? 347 PHE E CA  1 
ATOM   16962 C C   . PHE E 1 347 ? 63.707  74.817  22.451  1.00 41.65  ? 347 PHE E C   1 
ATOM   16963 O O   . PHE E 1 347 ? 64.455  74.498  23.381  1.00 37.48  ? 347 PHE E O   1 
ATOM   16964 C CB  . PHE E 1 347 ? 62.562  73.059  21.105  1.00 38.89  ? 347 PHE E CB  1 
ATOM   16965 C CG  . PHE E 1 347 ? 63.795  72.218  21.375  1.00 37.64  ? 347 PHE E CG  1 
ATOM   16966 C CD1 . PHE E 1 347 ? 63.940  71.544  22.576  1.00 34.68  ? 347 PHE E CD1 1 
ATOM   16967 C CD2 . PHE E 1 347 ? 64.838  72.180  20.459  1.00 41.41  ? 347 PHE E CD2 1 
ATOM   16968 C CE1 . PHE E 1 347 ? 65.088  70.816  22.839  1.00 40.31  ? 347 PHE E CE1 1 
ATOM   16969 C CE2 . PHE E 1 347 ? 65.981  71.435  20.718  1.00 44.00  ? 347 PHE E CE2 1 
ATOM   16970 C CZ  . PHE E 1 347 ? 66.113  70.770  21.920  1.00 42.64  ? 347 PHE E CZ  1 
ATOM   16971 N N   . LYS E 1 348 ? 63.997  75.819  21.614  1.00 43.30  ? 348 LYS E N   1 
ATOM   16972 C CA  . LYS E 1 348 ? 65.235  76.583  21.735  1.00 45.80  ? 348 LYS E CA  1 
ATOM   16973 C C   . LYS E 1 348 ? 65.357  77.233  23.111  1.00 39.18  ? 348 LYS E C   1 
ATOM   16974 O O   . LYS E 1 348 ? 66.458  77.351  23.632  1.00 39.28  ? 348 LYS E O   1 
ATOM   16975 C CB  . LYS E 1 348 ? 65.390  77.607  20.603  1.00 52.85  ? 348 LYS E CB  1 
ATOM   16976 C CG  . LYS E 1 348 ? 65.892  76.957  19.317  1.00 58.31  ? 348 LYS E CG  1 
ATOM   16977 C CD  . LYS E 1 348 ? 66.272  77.885  18.172  1.00 66.58  ? 348 LYS E CD  1 
ATOM   16978 C CE  . LYS E 1 348 ? 67.121  77.139  17.183  1.00 75.42  ? 348 LYS E CE  1 
ATOM   16979 N NZ  . LYS E 1 348 ? 66.961  77.676  15.830  1.00 76.66  ? 348 LYS E NZ  1 
ATOM   16980 N N   . ILE E 1 349 ? 64.233  77.628  23.711  1.00 34.55  ? 349 ILE E N   1 
ATOM   16981 C CA  . ILE E 1 349 ? 64.263  78.208  25.040  1.00 35.23  ? 349 ILE E CA  1 
ATOM   16982 C C   . ILE E 1 349 ? 64.559  77.093  26.048  1.00 35.50  ? 349 ILE E C   1 
ATOM   16983 O O   . ILE E 1 349 ? 65.374  77.256  26.959  1.00 37.36  ? 349 ILE E O   1 
ATOM   16984 C CB  . ILE E 1 349 ? 62.946  78.969  25.315  1.00 34.84  ? 349 ILE E CB  1 
ATOM   16985 C CG1 . ILE E 1 349 ? 62.762  80.111  24.299  1.00 38.79  ? 349 ILE E CG1 1 
ATOM   16986 C CG2 . ILE E 1 349 ? 62.863  79.479  26.756  1.00 33.21  ? 349 ILE E CG2 1 
ATOM   16987 C CD1 . ILE E 1 349 ? 61.666  81.130  24.612  1.00 37.43  ? 349 ILE E CD1 1 
ATOM   16988 N N   . VAL E 1 350 ? 63.887  75.954  25.877  1.00 31.71  ? 350 VAL E N   1 
ATOM   16989 C CA  . VAL E 1 350 ? 64.038  74.838  26.792  1.00 30.05  ? 350 VAL E CA  1 
ATOM   16990 C C   . VAL E 1 350 ? 65.502  74.398  26.774  1.00 31.41  ? 350 VAL E C   1 
ATOM   16991 O O   . VAL E 1 350 ? 66.056  74.128  27.828  1.00 29.56  ? 350 VAL E O   1 
ATOM   16992 C CB  . VAL E 1 350 ? 63.075  73.689  26.430  1.00 27.54  ? 350 VAL E CB  1 
ATOM   16993 C CG1 . VAL E 1 350 ? 63.512  72.323  26.946  1.00 29.84  ? 350 VAL E CG1 1 
ATOM   16994 C CG2 . VAL E 1 350 ? 61.657  73.980  26.885  1.00 28.62  ? 350 VAL E CG2 1 
ATOM   16995 N N   . SER E 1 351 ? 66.104  74.307  25.577  1.00 34.23  ? 351 SER E N   1 
ATOM   16996 C CA  . SER E 1 351 ? 67.495  73.887  25.412  1.00 35.07  ? 351 SER E CA  1 
ATOM   16997 C C   . SER E 1 351 ? 68.448  74.907  26.044  1.00 37.14  ? 351 SER E C   1 
ATOM   16998 O O   . SER E 1 351 ? 69.369  74.553  26.780  1.00 34.29  ? 351 SER E O   1 
ATOM   16999 C CB  . SER E 1 351 ? 67.828  73.689  23.977  1.00 34.20  ? 351 SER E CB  1 
ATOM   17000 O OG  . SER E 1 351 ? 69.147  73.198  23.867  1.00 32.68  ? 351 SER E OG  1 
ATOM   17001 N N   . LEU E 1 352 ? 68.183  76.189  25.792  1.00 36.57  ? 352 LEU E N   1 
ATOM   17002 C CA  . LEU E 1 352 ? 68.953  77.238  26.418  1.00 36.84  ? 352 LEU E CA  1 
ATOM   17003 C C   . LEU E 1 352 ? 68.875  77.098  27.934  1.00 38.45  ? 352 LEU E C   1 
ATOM   17004 O O   . LEU E 1 352 ? 69.891  77.221  28.607  1.00 39.27  ? 352 LEU E O   1 
ATOM   17005 C CB  . LEU E 1 352 ? 68.451  78.599  25.954  1.00 40.78  ? 352 LEU E CB  1 
ATOM   17006 C CG  . LEU E 1 352 ? 69.390  79.772  26.262  1.00 45.68  ? 352 LEU E CG  1 
ATOM   17007 C CD1 . LEU E 1 352 ? 70.679  79.738  25.410  1.00 38.06  ? 352 LEU E CD1 1 
ATOM   17008 C CD2 . LEU E 1 352 ? 68.613  81.074  26.088  1.00 49.49  ? 352 LEU E CD2 1 
ATOM   17009 N N   . CYS E 1 353 ? 67.670  76.855  28.463  1.00 37.39  ? 353 CYS E N   1 
ATOM   17010 C CA  . CYS E 1 353 ? 67.478  76.666  29.891  1.00 34.16  ? 353 CYS E CA  1 
ATOM   17011 C C   . CYS E 1 353 ? 68.407  75.566  30.413  1.00 35.88  ? 353 CYS E C   1 
ATOM   17012 O O   . CYS E 1 353 ? 68.952  75.707  31.511  1.00 32.39  ? 353 CYS E O   1 
ATOM   17013 C CB  . CYS E 1 353 ? 66.021  76.341  30.229  1.00 35.83  ? 353 CYS E CB  1 
ATOM   17014 S SG  . CYS E 1 353 ? 64.920  77.784  30.259  1.00 41.29  ? 353 CYS E SG  1 
ATOM   17015 N N   . TYR E 1 354 ? 68.584  74.479  29.629  1.00 35.61  ? 354 TYR E N   1 
ATOM   17016 C CA  . TYR E 1 354 ? 69.430  73.350  30.012  1.00 36.12  ? 354 TYR E CA  1 
ATOM   17017 C C   . TYR E 1 354 ? 70.867  73.787  30.275  1.00 39.74  ? 354 TYR E C   1 
ATOM   17018 O O   . TYR E 1 354 ? 71.524  73.226  31.132  1.00 39.34  ? 354 TYR E O   1 
ATOM   17019 C CB  . TYR E 1 354 ? 69.596  72.263  28.949  1.00 33.73  ? 354 TYR E CB  1 
ATOM   17020 C CG  . TYR E 1 354 ? 70.117  70.916  29.445  1.00 33.20  ? 354 TYR E CG  1 
ATOM   17021 C CD1 . TYR E 1 354 ? 69.912  70.476  30.752  1.00 32.74  ? 354 TYR E CD1 1 
ATOM   17022 C CD2 . TYR E 1 354 ? 70.757  70.042  28.578  1.00 32.75  ? 354 TYR E CD2 1 
ATOM   17023 C CE1 . TYR E 1 354 ? 70.337  69.226  31.180  1.00 32.00  ? 354 TYR E CE1 1 
ATOM   17024 C CE2 . TYR E 1 354 ? 71.191  68.792  28.991  1.00 31.92  ? 354 TYR E CE2 1 
ATOM   17025 C CZ  . TYR E 1 354 ? 70.980  68.383  30.294  1.00 32.77  ? 354 TYR E CZ  1 
ATOM   17026 O OH  . TYR E 1 354 ? 71.414  67.162  30.698  1.00 32.98  ? 354 TYR E OH  1 
ATOM   17027 N N   . GLU E 1 355 ? 71.361  74.753  29.494  1.00 48.58  ? 355 GLU E N   1 
ATOM   17028 C CA  . GLU E 1 355 ? 72.689  75.303  29.691  1.00 55.53  ? 355 GLU E CA  1 
ATOM   17029 C C   . GLU E 1 355 ? 72.735  76.245  30.901  1.00 56.74  ? 355 GLU E C   1 
ATOM   17030 O O   . GLU E 1 355 ? 73.610  76.105  31.751  1.00 64.08  ? 355 GLU E O   1 
ATOM   17031 C CB  . GLU E 1 355 ? 73.119  76.012  28.412  1.00 60.71  ? 355 GLU E CB  1 
ATOM   17032 C CG  . GLU E 1 355 ? 74.478  76.682  28.575  1.00 69.98  ? 355 GLU E CG  1 
ATOM   17033 C CD  . GLU E 1 355 ? 75.064  77.207  27.285  1.00 75.94  ? 355 GLU E CD  1 
ATOM   17034 O OE1 . GLU E 1 355 ? 76.166  77.780  27.407  1.00 78.71  ? 355 GLU E OE1 1 
ATOM   17035 O OE2 . GLU E 1 355 ? 74.447  77.052  26.201  1.00 73.95  ? 355 GLU E OE2 1 
ATOM   17036 N N   . VAL E 1 356 ? 71.765  77.169  31.000  1.00 48.61  ? 356 VAL E N   1 
ATOM   17037 C CA  . VAL E 1 356 ? 71.908  78.372  31.807  1.00 40.96  ? 356 VAL E CA  1 
ATOM   17038 C C   . VAL E 1 356 ? 71.430  78.189  33.244  1.00 42.44  ? 356 VAL E C   1 
ATOM   17039 O O   . VAL E 1 356 ? 71.991  78.773  34.178  1.00 42.57  ? 356 VAL E O   1 
ATOM   17040 C CB  . VAL E 1 356 ? 71.141  79.516  31.124  1.00 39.91  ? 356 VAL E CB  1 
ATOM   17041 C CG1 . VAL E 1 356 ? 70.809  80.665  32.079  1.00 39.72  ? 356 VAL E CG1 1 
ATOM   17042 C CG2 . VAL E 1 356 ? 71.897  80.011  29.899  1.00 40.40  ? 356 VAL E CG2 1 
ATOM   17043 N N   . ILE E 1 357 ? 70.328  77.462  33.406  1.00 43.84  ? 357 ILE E N   1 
ATOM   17044 C CA  . ILE E 1 357 ? 69.641  77.443  34.683  1.00 41.92  ? 357 ILE E CA  1 
ATOM   17045 C C   . ILE E 1 357 ? 70.503  76.672  35.682  1.00 42.22  ? 357 ILE E C   1 
ATOM   17046 O O   . ILE E 1 357 ? 70.694  77.124  36.813  1.00 42.85  ? 357 ILE E O   1 
ATOM   17047 C CB  . ILE E 1 357 ? 68.216  76.884  34.519  1.00 38.61  ? 357 ILE E CB  1 
ATOM   17048 C CG1 . ILE E 1 357 ? 67.414  77.697  33.476  1.00 39.09  ? 357 ILE E CG1 1 
ATOM   17049 C CG2 . ILE E 1 357 ? 67.500  76.782  35.867  1.00 37.69  ? 357 ILE E CG2 1 
ATOM   17050 C CD1 . ILE E 1 357 ? 67.136  79.153  33.823  1.00 38.71  ? 357 ILE E CD1 1 
ATOM   17051 N N   . PRO E 1 358 ? 71.086  75.512  35.302  1.00 42.89  ? 358 PRO E N   1 
ATOM   17052 C CA  . PRO E 1 358 ? 71.932  74.762  36.239  1.00 45.57  ? 358 PRO E CA  1 
ATOM   17053 C C   . PRO E 1 358 ? 73.097  75.586  36.796  1.00 47.39  ? 358 PRO E C   1 
ATOM   17054 O O   . PRO E 1 358 ? 73.424  75.459  37.975  1.00 44.91  ? 358 PRO E O   1 
ATOM   17055 C CB  . PRO E 1 358 ? 72.398  73.545  35.409  1.00 41.87  ? 358 PRO E CB  1 
ATOM   17056 C CG  . PRO E 1 358 ? 71.345  73.417  34.322  1.00 38.98  ? 358 PRO E CG  1 
ATOM   17057 C CD  . PRO E 1 358 ? 70.955  74.846  33.991  1.00 38.25  ? 358 PRO E CD  1 
ATOM   17058 N N   . GLU E 1 359 ? 73.704  76.439  35.952  1.00 52.75  ? 359 GLU E N   1 
ATOM   17059 C CA  . GLU E 1 359 ? 74.818  77.288  36.369  1.00 60.68  ? 359 GLU E CA  1 
ATOM   17060 C C   . GLU E 1 359 ? 74.307  78.317  37.380  1.00 58.98  ? 359 GLU E C   1 
ATOM   17061 O O   . GLU E 1 359 ? 74.910  78.509  38.432  1.00 60.69  ? 359 GLU E O   1 
ATOM   17062 C CB  . GLU E 1 359 ? 75.560  77.971  35.208  1.00 66.86  ? 359 GLU E CB  1 
ATOM   17063 C CG  . GLU E 1 359 ? 76.381  77.028  34.321  1.00 77.38  ? 359 GLU E CG  1 
ATOM   17064 C CD  . GLU E 1 359 ? 77.246  75.977  35.029  1.00 87.66  ? 359 GLU E CD  1 
ATOM   17065 O OE1 . GLU E 1 359 ? 77.185  74.796  34.611  1.00 83.77  ? 359 GLU E OE1 1 
ATOM   17066 O OE2 . GLU E 1 359 ? 77.960  76.300  36.013  1.00 84.99  ? 359 GLU E OE2 1 
ATOM   17067 N N   . VAL E 1 360 ? 73.167  78.943  37.073  1.00 53.13  ? 360 VAL E N   1 
ATOM   17068 C CA  . VAL E 1 360 ? 72.582  79.921  37.968  1.00 48.28  ? 360 VAL E CA  1 
ATOM   17069 C C   . VAL E 1 360 ? 72.166  79.213  39.257  1.00 48.90  ? 360 VAL E C   1 
ATOM   17070 O O   . VAL E 1 360 ? 72.322  79.753  40.346  1.00 45.78  ? 360 VAL E O   1 
ATOM   17071 C CB  . VAL E 1 360 ? 71.406  80.660  37.295  1.00 52.32  ? 360 VAL E CB  1 
ATOM   17072 C CG1 . VAL E 1 360 ? 70.677  81.580  38.261  1.00 49.07  ? 360 VAL E CG1 1 
ATOM   17073 C CG2 . VAL E 1 360 ? 71.831  81.467  36.070  1.00 53.41  ? 360 VAL E CG2 1 
ATOM   17074 N N   . LEU E 1 361 ? 71.659  77.984  39.161  1.00 51.40  ? 361 LEU E N   1 
ATOM   17075 C CA  . LEU E 1 361 ? 71.274  77.282  40.377  1.00 58.36  ? 361 LEU E CA  1 
ATOM   17076 C C   . LEU E 1 361 ? 72.497  76.825  41.182  1.00 51.40  ? 361 LEU E C   1 
ATOM   17077 O O   . LEU E 1 361 ? 72.372  76.646  42.385  1.00 49.28  ? 361 LEU E O   1 
ATOM   17078 C CB  . LEU E 1 361 ? 70.300  76.129  40.117  1.00 63.13  ? 361 LEU E CB  1 
ATOM   17079 C CG  . LEU E 1 361 ? 68.845  76.522  39.819  1.00 59.38  ? 361 LEU E CG  1 
ATOM   17080 C CD1 . LEU E 1 361 ? 68.061  75.311  39.357  1.00 59.43  ? 361 LEU E CD1 1 
ATOM   17081 C CD2 . LEU E 1 361 ? 68.160  77.138  41.015  1.00 57.40  ? 361 LEU E CD2 1 
ATOM   17082 N N   . LYS E 1 362 ? 73.667  76.623  40.558  1.00 56.60  ? 362 LYS E N   1 
ATOM   17083 C CA  . LYS E 1 362 ? 74.858  76.247  41.317  1.00 58.22  ? 362 LYS E CA  1 
ATOM   17084 C C   . LYS E 1 362 ? 75.352  77.440  42.136  1.00 64.53  ? 362 LYS E C   1 
ATOM   17085 O O   . LYS E 1 362 ? 75.486  77.339  43.360  1.00 58.21  ? 362 LYS E O   1 
ATOM   17086 C CB  . LYS E 1 362 ? 75.975  75.675  40.441  1.00 59.82  ? 362 LYS E CB  1 
ATOM   17087 C CG  . LYS E 1 362 ? 75.887  74.164  40.260  1.00 67.03  ? 362 LYS E CG  1 
ATOM   17088 C CD  . LYS E 1 362 ? 76.594  73.645  39.010  1.00 70.01  ? 362 LYS E CD  1 
ATOM   17089 C CE  . LYS E 1 362 ? 76.771  72.151  39.002  1.00 67.06  ? 362 LYS E CE  1 
ATOM   17090 N NZ  . LYS E 1 362 ? 77.108  71.656  37.663  1.00 61.85  ? 362 LYS E NZ  1 
ATOM   17091 N N   . LYS E 1 363 ? 75.578  78.567  41.444  1.00 71.43  ? 363 LYS E N   1 
ATOM   17092 C CA  . LYS E 1 363 ? 76.009  79.807  42.069  1.00 77.90  ? 363 LYS E CA  1 
ATOM   17093 C C   . LYS E 1 363 ? 75.059  80.206  43.194  1.00 78.02  ? 363 LYS E C   1 
ATOM   17094 O O   . LYS E 1 363 ? 75.521  80.468  44.295  1.00 79.53  ? 363 LYS E O   1 
ATOM   17095 C CB  . LYS E 1 363 ? 76.151  80.927  41.034  1.00 84.77  ? 363 LYS E CB  1 
ATOM   17096 C CG  . LYS E 1 363 ? 77.408  80.789  40.199  1.00 92.71  ? 363 LYS E CG  1 
ATOM   17097 C CD  . LYS E 1 363 ? 77.387  81.594  38.908  1.00 99.46  ? 363 LYS E CD  1 
ATOM   17098 C CE  . LYS E 1 363 ? 78.710  81.585  38.222  1.00 94.71  ? 363 LYS E CE  1 
ATOM   17099 N NZ  . LYS E 1 363 ? 78.562  82.151  36.883  1.00 95.09  ? 363 LYS E NZ  1 
ATOM   17100 N N   . HIS E 1 364 ? 73.746  80.243  42.929  1.00 81.36  ? 364 HIS E N   1 
ATOM   17101 C CA  . HIS E 1 364 ? 72.772  80.613  43.949  1.00 80.81  ? 364 HIS E CA  1 
ATOM   17102 C C   . HIS E 1 364 ? 72.859  79.666  45.147  1.00 94.30  ? 364 HIS E C   1 
ATOM   17103 O O   . HIS E 1 364 ? 72.514  80.060  46.260  1.00 106.11 ? 364 HIS E O   1 
ATOM   17104 C CB  . HIS E 1 364 ? 71.361  80.662  43.362  1.00 83.94  ? 364 HIS E CB  1 
ATOM   17105 C CG  . HIS E 1 364 ? 70.323  81.265  44.252  1.00 88.28  ? 364 HIS E CG  1 
ATOM   17106 N ND1 . HIS E 1 364 ? 70.170  82.628  44.417  1.00 97.39  ? 364 HIS E ND1 1 
ATOM   17107 C CD2 . HIS E 1 364 ? 69.364  80.688  44.991  1.00 84.71  ? 364 HIS E CD2 1 
ATOM   17108 C CE1 . HIS E 1 364 ? 69.161  82.857  45.247  1.00 94.36  ? 364 HIS E CE1 1 
ATOM   17109 N NE2 . HIS E 1 364 ? 68.658  81.691  45.609  1.00 90.13  ? 364 HIS E NE2 1 
ATOM   17110 N N   . GLY E 1 365 ? 73.271  78.408  44.904  1.00 102.82 ? 365 GLY E N   1 
ATOM   17111 C CA  . GLY E 1 365 ? 73.764  77.506  45.940  1.00 94.05  ? 365 GLY E CA  1 
ATOM   17112 C C   . GLY E 1 365 ? 72.681  76.995  46.894  1.00 101.16 ? 365 GLY E C   1 
ATOM   17113 O O   . GLY E 1 365 ? 73.013  76.250  47.814  1.00 82.48  ? 365 GLY E O   1 
ATOM   17114 N N   . LYS E 1 366 ? 71.408  77.381  46.667  1.00 117.35 ? 366 LYS E N   1 
ATOM   17115 C CA  . LYS E 1 366 ? 70.277  76.992  47.507  1.00 121.62 ? 366 LYS E CA  1 
ATOM   17116 C C   . LYS E 1 366 ? 69.764  75.600  47.131  1.00 127.13 ? 366 LYS E C   1 
ATOM   17117 O O   . LYS E 1 366 ? 69.204  74.899  47.971  1.00 117.00 ? 366 LYS E O   1 
ATOM   17118 C CB  . LYS E 1 366 ? 69.055  77.911  47.374  1.00 120.76 ? 366 LYS E CB  1 
ATOM   17119 C CG  . LYS E 1 366 ? 69.188  79.350  47.869  1.00 130.44 ? 366 LYS E CG  1 
ATOM   17120 C CD  . LYS E 1 366 ? 69.435  79.547  49.362  1.00 131.20 ? 366 LYS E CD  1 
ATOM   17121 C CE  . LYS E 1 366 ? 70.887  79.691  49.722  1.00 127.46 ? 366 LYS E CE  1 
ATOM   17122 N NZ  . LYS E 1 366 ? 71.091  79.865  51.164  1.00 123.26 ? 366 LYS E NZ  1 
ATOM   17123 N N   . ALA E 1 367 ? 69.912  75.227  45.854  1.00 124.75 ? 367 ALA E N   1 
ATOM   17124 C CA  . ALA E 1 367 ? 69.452  73.937  45.369  1.00 115.38 ? 367 ALA E CA  1 
ATOM   17125 C C   . ALA E 1 367 ? 70.507  72.866  45.647  1.00 113.46 ? 367 ALA E C   1 
ATOM   17126 O O   . ALA E 1 367 ? 71.673  73.035  45.289  1.00 114.42 ? 367 ALA E O   1 
ATOM   17127 C CB  . ALA E 1 367 ? 69.131  74.051  43.892  1.00 113.12 ? 367 ALA E CB  1 
ATOM   17128 N N   . LYS E 1 368 ? 70.082  71.766  46.293  1.00 106.53 ? 368 LYS E N   1 
ATOM   17129 C CA  . LYS E 1 368 ? 70.895  70.562  46.425  1.00 99.82  ? 368 LYS E CA  1 
ATOM   17130 C C   . LYS E 1 368 ? 70.887  69.790  45.100  1.00 90.84  ? 368 LYS E C   1 
ATOM   17131 O O   . LYS E 1 368 ? 71.612  68.804  44.952  1.00 92.73  ? 368 LYS E O   1 
ATOM   17132 C CB  . LYS E 1 368 ? 70.399  69.674  47.577  1.00 92.47  ? 368 LYS E CB  1 
ATOM   17133 N N   . ASN E 1 369 ? 70.032  70.228  44.160  1.00 71.78  ? 369 ASN E N   1 
ATOM   17134 C CA  . ASN E 1 369 ? 70.013  69.735  42.792  1.00 60.07  ? 369 ASN E CA  1 
ATOM   17135 C C   . ASN E 1 369 ? 69.774  70.900  41.834  1.00 52.96  ? 369 ASN E C   1 
ATOM   17136 O O   . ASN E 1 369 ? 68.769  71.590  41.953  1.00 60.70  ? 369 ASN E O   1 
ATOM   17137 C CB  . ASN E 1 369 ? 68.924  68.689  42.606  1.00 60.84  ? 369 ASN E CB  1 
ATOM   17138 C CG  . ASN E 1 369 ? 68.894  68.136  41.203  1.00 61.08  ? 369 ASN E CG  1 
ATOM   17139 O OD1 . ASN E 1 369 ? 69.846  68.324  40.441  1.00 65.99  ? 369 ASN E OD1 1 
ATOM   17140 N ND2 . ASN E 1 369 ? 67.820  67.449  40.842  1.00 64.64  ? 369 ASN E ND2 1 
ATOM   17141 N N   . PRO E 1 370 ? 70.701  71.204  40.899  1.00 46.97  ? 370 PRO E N   1 
ATOM   17142 C CA  . PRO E 1 370 ? 70.450  72.214  39.855  1.00 48.77  ? 370 PRO E CA  1 
ATOM   17143 C C   . PRO E 1 370 ? 69.870  71.757  38.513  1.00 45.82  ? 370 PRO E C   1 
ATOM   17144 O O   . PRO E 1 370 ? 69.836  72.519  37.541  1.00 40.08  ? 370 PRO E O   1 
ATOM   17145 C CB  . PRO E 1 370 ? 71.893  72.711  39.659  1.00 49.65  ? 370 PRO E CB  1 
ATOM   17146 C CG  . PRO E 1 370 ? 72.716  71.438  39.716  1.00 48.39  ? 370 PRO E CG  1 
ATOM   17147 C CD  . PRO E 1 370 ? 72.072  70.660  40.864  1.00 44.95  ? 370 PRO E CD  1 
ATOM   17148 N N   . TRP E 1 371 ? 69.459  70.488  38.452  1.00 45.39  ? 371 TRP E N   1 
ATOM   17149 C CA  . TRP E 1 371 ? 69.157  69.838  37.186  1.00 47.35  ? 371 TRP E CA  1 
ATOM   17150 C C   . TRP E 1 371 ? 67.648  69.659  36.976  1.00 40.69  ? 371 TRP E C   1 
ATOM   17151 O O   . TRP E 1 371 ? 66.860  69.608  37.932  1.00 40.75  ? 371 TRP E O   1 
ATOM   17152 C CB  . TRP E 1 371 ? 69.888  68.488  37.121  1.00 49.40  ? 371 TRP E CB  1 
ATOM   17153 C CG  . TRP E 1 371 ? 71.384  68.569  37.264  1.00 47.55  ? 371 TRP E CG  1 
ATOM   17154 C CD1 . TRP E 1 371 ? 72.134  68.061  38.285  1.00 46.03  ? 371 TRP E CD1 1 
ATOM   17155 C CD2 . TRP E 1 371 ? 72.314  69.177  36.342  1.00 45.87  ? 371 TRP E CD2 1 
ATOM   17156 N NE1 . TRP E 1 371 ? 73.459  68.313  38.063  1.00 46.06  ? 371 TRP E NE1 1 
ATOM   17157 C CE2 . TRP E 1 371 ? 73.606  68.993  36.884  1.00 46.01  ? 371 TRP E CE2 1 
ATOM   17158 C CE3 . TRP E 1 371 ? 72.192  69.846  35.119  1.00 44.87  ? 371 TRP E CE3 1 
ATOM   17159 C CZ2 . TRP E 1 371 ? 74.756  69.448  36.241  1.00 41.31  ? 371 TRP E CZ2 1 
ATOM   17160 C CZ3 . TRP E 1 371 ? 73.332  70.300  34.484  1.00 44.95  ? 371 TRP E CZ3 1 
ATOM   17161 C CH2 . TRP E 1 371 ? 74.596  70.100  35.038  1.00 41.44  ? 371 TRP E CH2 1 
ATOM   17162 N N   . PRO E 1 372 ? 67.195  69.524  35.705  1.00 39.85  ? 372 PRO E N   1 
ATOM   17163 C CA  . PRO E 1 372 ? 65.779  69.342  35.405  1.00 36.66  ? 372 PRO E CA  1 
ATOM   17164 C C   . PRO E 1 372 ? 65.279  67.898  35.453  1.00 33.82  ? 372 PRO E C   1 
ATOM   17165 O O   . PRO E 1 372 ? 66.061  66.938  35.515  1.00 31.52  ? 372 PRO E O   1 
ATOM   17166 C CB  . PRO E 1 372 ? 65.709  69.950  34.001  1.00 37.38  ? 372 PRO E CB  1 
ATOM   17167 C CG  . PRO E 1 372 ? 66.970  69.492  33.353  1.00 38.79  ? 372 PRO E CG  1 
ATOM   17168 C CD  . PRO E 1 372 ? 68.002  69.548  34.472  1.00 41.58  ? 372 PRO E CD  1 
ATOM   17169 N N   . ASN E 1 373 ? 63.945  67.794  35.444  1.00 33.54  ? 373 ASN E N   1 
ATOM   17170 C CA  . ASN E 1 373 ? 63.220  66.539  35.426  1.00 34.32  ? 373 ASN E CA  1 
ATOM   17171 C C   . ASN E 1 373 ? 62.399  66.468  34.144  1.00 30.12  ? 373 ASN E C   1 
ATOM   17172 O O   . ASN E 1 373 ? 62.397  67.411  33.354  1.00 27.78  ? 373 ASN E O   1 
ATOM   17173 C CB  . ASN E 1 373 ? 62.363  66.331  36.677  1.00 39.26  ? 373 ASN E CB  1 
ATOM   17174 C CG  . ASN E 1 373 ? 61.263  67.357  36.846  1.00 41.64  ? 373 ASN E CG  1 
ATOM   17175 O OD1 . ASN E 1 373 ? 60.607  67.769  35.889  1.00 46.28  ? 373 ASN E OD1 1 
ATOM   17176 N ND2 . ASN E 1 373 ? 61.056  67.810  38.065  1.00 46.01  ? 373 ASN E ND2 1 
ATOM   17177 N N   . VAL E 1 374 ? 61.713  65.336  33.990  1.00 28.77  ? 374 VAL E N   1 
ATOM   17178 C CA  . VAL E 1 374 ? 60.890  65.035  32.831  1.00 33.35  ? 374 VAL E CA  1 
ATOM   17179 C C   . VAL E 1 374 ? 59.971  66.205  32.484  1.00 30.41  ? 374 VAL E C   1 
ATOM   17180 O O   . VAL E 1 374 ? 59.784  66.548  31.323  1.00 27.88  ? 374 VAL E O   1 
ATOM   17181 C CB  . VAL E 1 374 ? 60.099  63.736  33.101  1.00 37.26  ? 374 VAL E CB  1 
ATOM   17182 C CG1 . VAL E 1 374 ? 59.118  63.871  34.264  1.00 39.87  ? 374 VAL E CG1 1 
ATOM   17183 C CG2 . VAL E 1 374 ? 59.379  63.209  31.859  1.00 39.49  ? 374 VAL E CG2 1 
ATOM   17184 N N   . ASP E 1 375 ? 59.390  66.829  33.501  1.00 32.16  ? 375 ASP E N   1 
ATOM   17185 C CA  . ASP E 1 375 ? 58.315  67.783  33.293  1.00 31.78  ? 375 ASP E CA  1 
ATOM   17186 C C   . ASP E 1 375 ? 58.840  69.063  32.649  1.00 32.90  ? 375 ASP E C   1 
ATOM   17187 O O   . ASP E 1 375 ? 58.065  69.902  32.186  1.00 33.36  ? 375 ASP E O   1 
ATOM   17188 C CB  . ASP E 1 375 ? 57.576  68.020  34.599  1.00 34.70  ? 375 ASP E CB  1 
ATOM   17189 C CG  . ASP E 1 375 ? 56.868  66.791  35.167  1.00 38.37  ? 375 ASP E CG  1 
ATOM   17190 O OD1 . ASP E 1 375 ? 56.334  65.992  34.364  1.00 34.00  ? 375 ASP E OD1 1 
ATOM   17191 O OD2 . ASP E 1 375 ? 56.834  66.661  36.412  1.00 42.25  ? 375 ASP E OD2 1 
ATOM   17192 N N   . ALA E 1 376 ? 60.163  69.235  32.642  1.00 33.01  ? 376 ALA E N   1 
ATOM   17193 C CA  . ALA E 1 376 ? 60.738  70.436  32.064  1.00 32.06  ? 376 ALA E CA  1 
ATOM   17194 C C   . ALA E 1 376 ? 60.799  70.315  30.544  1.00 30.28  ? 376 ALA E C   1 
ATOM   17195 O O   . ALA E 1 376 ? 61.018  71.330  29.889  1.00 36.07  ? 376 ALA E O   1 
ATOM   17196 C CB  . ALA E 1 376 ? 62.108  70.715  32.657  1.00 33.66  ? 376 ALA E CB  1 
ATOM   17197 N N   . HIS E 1 377 ? 60.610  69.104  29.991  1.00 27.55  ? 377 HIS E N   1 
ATOM   17198 C CA  . HIS E 1 377 ? 60.776  68.889  28.556  1.00 29.24  ? 377 HIS E CA  1 
ATOM   17199 C C   . HIS E 1 377 ? 59.480  68.516  27.834  1.00 28.08  ? 377 HIS E C   1 
ATOM   17200 O O   . HIS E 1 377 ? 59.363  68.810  26.652  1.00 28.06  ? 377 HIS E O   1 
ATOM   17201 C CB  . HIS E 1 377 ? 61.861  67.843  28.259  1.00 27.87  ? 377 HIS E CB  1 
ATOM   17202 C CG  . HIS E 1 377 ? 62.702  68.208  27.086  1.00 30.61  ? 377 HIS E CG  1 
ATOM   17203 N ND1 . HIS E 1 377 ? 62.183  68.557  25.862  1.00 34.32  ? 377 HIS E ND1 1 
ATOM   17204 C CD2 . HIS E 1 377 ? 64.029  68.285  26.952  1.00 34.02  ? 377 HIS E CD2 1 
ATOM   17205 C CE1 . HIS E 1 377 ? 63.181  68.835  25.030  1.00 36.28  ? 377 HIS E CE1 1 
ATOM   17206 N NE2 . HIS E 1 377 ? 64.315  68.676  25.673  1.00 34.59  ? 377 HIS E NE2 1 
ATOM   17207 N N   . SER E 1 378 ? 58.513  67.895  28.530  1.00 29.71  ? 378 SER E N   1 
ATOM   17208 C CA  . SER E 1 378 ? 57.397  67.208  27.878  1.00 31.16  ? 378 SER E CA  1 
ATOM   17209 C C   . SER E 1 378 ? 56.414  68.164  27.177  1.00 29.58  ? 378 SER E C   1 
ATOM   17210 O O   . SER E 1 378 ? 55.933  67.851  26.098  1.00 27.00  ? 378 SER E O   1 
ATOM   17211 C CB  . SER E 1 378 ? 56.696  66.272  28.843  1.00 30.68  ? 378 SER E CB  1 
ATOM   17212 O OG  . SER E 1 378 ? 56.218  66.940  30.002  1.00 29.71  ? 378 SER E OG  1 
ATOM   17213 N N   . GLY E 1 379 ? 56.181  69.360  27.734  1.00 28.72  ? 379 GLY E N   1 
ATOM   17214 C CA  . GLY E 1 379 ? 55.251  70.320  27.164  1.00 29.14  ? 379 GLY E CA  1 
ATOM   17215 C C   . GLY E 1 379 ? 55.578  70.739  25.725  1.00 29.47  ? 379 GLY E C   1 
ATOM   17216 O O   . GLY E 1 379 ? 54.711  70.651  24.855  1.00 30.67  ? 379 GLY E O   1 
ATOM   17217 N N   . VAL E 1 380 ? 56.798  71.232  25.482  1.00 28.76  ? 380 VAL E N   1 
ATOM   17218 C CA  . VAL E 1 380 ? 57.156  71.782  24.183  1.00 30.52  ? 380 VAL E CA  1 
ATOM   17219 C C   . VAL E 1 380 ? 57.082  70.687  23.124  1.00 29.18  ? 380 VAL E C   1 
ATOM   17220 O O   . VAL E 1 380 ? 56.813  70.994  21.980  1.00 34.21  ? 380 VAL E O   1 
ATOM   17221 C CB  . VAL E 1 380 ? 58.535  72.468  24.095  1.00 34.40  ? 380 VAL E CB  1 
ATOM   17222 C CG1 . VAL E 1 380 ? 58.583  73.734  24.938  1.00 36.14  ? 380 VAL E CG1 1 
ATOM   17223 C CG2 . VAL E 1 380 ? 59.691  71.532  24.461  1.00 34.81  ? 380 VAL E CG2 1 
ATOM   17224 N N   . LEU E 1 381 ? 57.299  69.420  23.489  1.00 28.10  ? 381 LEU E N   1 
ATOM   17225 C CA  . LEU E 1 381 ? 57.149  68.332  22.535  1.00 26.49  ? 381 LEU E CA  1 
ATOM   17226 C C   . LEU E 1 381 ? 55.698  68.195  22.095  1.00 27.98  ? 381 LEU E C   1 
ATOM   17227 O O   . LEU E 1 381 ? 55.422  68.133  20.896  1.00 30.52  ? 381 LEU E O   1 
ATOM   17228 C CB  . LEU E 1 381 ? 57.660  67.019  23.115  1.00 26.06  ? 381 LEU E CB  1 
ATOM   17229 C CG  . LEU E 1 381 ? 59.145  67.003  23.489  1.00 26.61  ? 381 LEU E CG  1 
ATOM   17230 C CD1 . LEU E 1 381 ? 59.554  65.623  23.968  1.00 28.52  ? 381 LEU E CD1 1 
ATOM   17231 C CD2 . LEU E 1 381 ? 59.981  67.409  22.299  1.00 26.92  ? 381 LEU E CD2 1 
ATOM   17232 N N   . LEU E 1 382 ? 54.783  68.124  23.070  1.00 29.21  ? 382 LEU E N   1 
ATOM   17233 C CA  . LEU E 1 382 ? 53.350  68.032  22.794  1.00 29.03  ? 382 LEU E CA  1 
ATOM   17234 C C   . LEU E 1 382 ? 52.893  69.239  21.974  1.00 27.23  ? 382 LEU E C   1 
ATOM   17235 O O   . LEU E 1 382 ? 52.277  69.058  20.941  1.00 23.94  ? 382 LEU E O   1 
ATOM   17236 C CB  . LEU E 1 382 ? 52.555  67.901  24.097  1.00 27.66  ? 382 LEU E CB  1 
ATOM   17237 C CG  . LEU E 1 382 ? 52.689  66.552  24.813  1.00 27.01  ? 382 LEU E CG  1 
ATOM   17238 C CD1 . LEU E 1 382 ? 52.040  66.517  26.200  1.00 30.73  ? 382 LEU E CD1 1 
ATOM   17239 C CD2 . LEU E 1 382 ? 52.130  65.452  23.955  1.00 24.11  ? 382 LEU E CD2 1 
ATOM   17240 N N   . TRP E 1 383 ? 53.254  70.449  22.421  1.00 27.58  ? 383 TRP E N   1 
ATOM   17241 C CA  . TRP E 1 383 ? 52.845  71.682  21.775  1.00 27.49  ? 383 TRP E CA  1 
ATOM   17242 C C   . TRP E 1 383 ? 53.377  71.741  20.351  1.00 30.96  ? 383 TRP E C   1 
ATOM   17243 O O   . TRP E 1 383 ? 52.666  72.152  19.446  1.00 36.44  ? 383 TRP E O   1 
ATOM   17244 C CB  . TRP E 1 383 ? 53.329  72.875  22.600  1.00 28.69  ? 383 TRP E CB  1 
ATOM   17245 C CG  . TRP E 1 383 ? 52.796  74.194  22.124  1.00 31.43  ? 383 TRP E CG  1 
ATOM   17246 C CD1 . TRP E 1 383 ? 53.340  74.983  21.151  1.00 31.37  ? 383 TRP E CD1 1 
ATOM   17247 C CD2 . TRP E 1 383 ? 51.598  74.866  22.570  1.00 36.80  ? 383 TRP E CD2 1 
ATOM   17248 N NE1 . TRP E 1 383 ? 52.597  76.120  20.993  1.00 34.68  ? 383 TRP E NE1 1 
ATOM   17249 C CE2 . TRP E 1 383 ? 51.510  76.069  21.830  1.00 37.91  ? 383 TRP E CE2 1 
ATOM   17250 C CE3 . TRP E 1 383 ? 50.590  74.571  23.497  1.00 38.64  ? 383 TRP E CE3 1 
ATOM   17251 C CZ2 . TRP E 1 383 ? 50.462  76.970  22.006  1.00 37.04  ? 383 TRP E CZ2 1 
ATOM   17252 C CZ3 . TRP E 1 383 ? 49.549  75.459  23.661  1.00 36.65  ? 383 TRP E CZ3 1 
ATOM   17253 C CH2 . TRP E 1 383 ? 49.489  76.642  22.924  1.00 36.13  ? 383 TRP E CH2 1 
ATOM   17254 N N   . HIS E 1 384 ? 54.613  71.274  20.140  1.00 32.46  ? 384 HIS E N   1 
ATOM   17255 C CA  . HIS E 1 384 ? 55.205  71.272  18.816  1.00 30.09  ? 384 HIS E CA  1 
ATOM   17256 C C   . HIS E 1 384 ? 54.283  70.628  17.787  1.00 28.43  ? 384 HIS E C   1 
ATOM   17257 O O   . HIS E 1 384 ? 54.190  71.110  16.671  1.00 27.26  ? 384 HIS E O   1 
ATOM   17258 C CB  . HIS E 1 384 ? 56.533  70.507  18.775  1.00 30.51  ? 384 HIS E CB  1 
ATOM   17259 C CG  . HIS E 1 384 ? 57.143  70.508  17.407  1.00 29.54  ? 384 HIS E CG  1 
ATOM   17260 N ND1 . HIS E 1 384 ? 57.591  71.661  16.788  1.00 28.15  ? 384 HIS E ND1 1 
ATOM   17261 C CD2 . HIS E 1 384 ? 57.329  69.520  16.541  1.00 27.43  ? 384 HIS E CD2 1 
ATOM   17262 C CE1 . HIS E 1 384 ? 58.055  71.358  15.585  1.00 27.81  ? 384 HIS E CE1 1 
ATOM   17263 N NE2 . HIS E 1 384 ? 57.919  70.063  15.423  1.00 27.52  ? 384 HIS E NE2 1 
ATOM   17264 N N   . TYR E 1 385 ? 53.643  69.521  18.164  1.00 28.09  ? 385 TYR E N   1 
ATOM   17265 C CA  . TYR E 1 385 ? 52.890  68.721  17.223  1.00 27.88  ? 385 TYR E CA  1 
ATOM   17266 C C   . TYR E 1 385 ? 51.398  69.078  17.248  1.00 29.22  ? 385 TYR E C   1 
ATOM   17267 O O   . TYR E 1 385 ? 50.593  68.450  16.569  1.00 28.21  ? 385 TYR E O   1 
ATOM   17268 C CB  . TYR E 1 385 ? 53.229  67.273  17.590  1.00 31.00  ? 385 TYR E CB  1 
ATOM   17269 C CG  . TYR E 1 385 ? 54.618  66.803  17.188  1.00 32.75  ? 385 TYR E CG  1 
ATOM   17270 C CD1 . TYR E 1 385 ? 54.937  66.597  15.851  1.00 36.57  ? 385 TYR E CD1 1 
ATOM   17271 C CD2 . TYR E 1 385 ? 55.611  66.574  18.128  1.00 32.92  ? 385 TYR E CD2 1 
ATOM   17272 C CE1 . TYR E 1 385 ? 56.195  66.176  15.459  1.00 33.65  ? 385 TYR E CE1 1 
ATOM   17273 C CE2 . TYR E 1 385 ? 56.873  66.159  17.749  1.00 33.38  ? 385 TYR E CE2 1 
ATOM   17274 C CZ  . TYR E 1 385 ? 57.165  65.950  16.413  1.00 33.62  ? 385 TYR E CZ  1 
ATOM   17275 O OH  . TYR E 1 385 ? 58.400  65.529  16.007  1.00 33.41  ? 385 TYR E OH  1 
ATOM   17276 N N   . GLY E 1 386 ? 50.995  70.094  18.015  1.00 31.79  ? 386 GLY E N   1 
ATOM   17277 C CA  . GLY E 1 386 ? 49.614  70.565  17.956  1.00 31.45  ? 386 GLY E CA  1 
ATOM   17278 C C   . GLY E 1 386 ? 48.677  69.948  19.005  1.00 32.93  ? 386 GLY E C   1 
ATOM   17279 O O   . GLY E 1 386 ? 47.456  70.025  18.841  1.00 32.81  ? 386 GLY E O   1 
ATOM   17280 N N   . ILE E 1 387 ? 49.233  69.325  20.063  1.00 31.86  ? 387 ILE E N   1 
ATOM   17281 C CA  . ILE E 1 387 ? 48.488  68.990  21.264  1.00 29.78  ? 387 ILE E CA  1 
ATOM   17282 C C   . ILE E 1 387 ? 48.681  70.134  22.255  1.00 28.88  ? 387 ILE E C   1 
ATOM   17283 O O   . ILE E 1 387 ? 49.662  70.162  22.971  1.00 27.80  ? 387 ILE E O   1 
ATOM   17284 C CB  . ILE E 1 387 ? 48.923  67.640  21.854  1.00 29.48  ? 387 ILE E CB  1 
ATOM   17285 C CG1 . ILE E 1 387 ? 48.662  66.467  20.911  1.00 33.12  ? 387 ILE E CG1 1 
ATOM   17286 C CG2 . ILE E 1 387 ? 48.193  67.399  23.166  1.00 30.31  ? 387 ILE E CG2 1 
ATOM   17287 C CD1 . ILE E 1 387 ? 49.796  66.118  19.969  1.00 34.10  ? 387 ILE E CD1 1 
ATOM   17288 N N   . ARG E 1 388 ? 47.743  71.080  22.251  1.00 31.01  ? 388 ARG E N   1 
ATOM   17289 C CA  . ARG E 1 388 ? 47.898  72.373  22.892  1.00 36.14  ? 388 ARG E CA  1 
ATOM   17290 C C   . ARG E 1 388 ? 46.905  72.574  24.034  1.00 33.03  ? 388 ARG E C   1 
ATOM   17291 O O   . ARG E 1 388 ? 46.844  73.661  24.606  1.00 30.88  ? 388 ARG E O   1 
ATOM   17292 C CB  . ARG E 1 388 ? 47.598  73.465  21.862  1.00 38.35  ? 388 ARG E CB  1 
ATOM   17293 C CG  . ARG E 1 388 ? 48.632  73.483  20.756  1.00 46.27  ? 388 ARG E CG  1 
ATOM   17294 C CD  . ARG E 1 388 ? 48.439  74.598  19.748  1.00 55.12  ? 388 ARG E CD  1 
ATOM   17295 N NE  . ARG E 1 388 ? 49.551  74.376  18.817  1.00 65.05  ? 388 ARG E NE  1 
ATOM   17296 C CZ  . ARG E 1 388 ? 50.343  75.293  18.274  1.00 57.14  ? 388 ARG E CZ  1 
ATOM   17297 N NH1 . ARG E 1 388 ? 49.967  76.560  18.248  1.00 51.69  ? 388 ARG E NH1 1 
ATOM   17298 N NH2 . ARG E 1 388 ? 51.475  74.913  17.703  1.00 52.17  ? 388 ARG E NH2 1 
ATOM   17299 N N   . GLU E 1 389 ? 46.127  71.532  24.334  1.00 28.89  ? 389 GLU E N   1 
ATOM   17300 C CA  . GLU E 1 389 ? 45.061  71.612  25.314  1.00 28.84  ? 389 GLU E CA  1 
ATOM   17301 C C   . GLU E 1 389 ? 45.595  71.282  26.717  1.00 27.53  ? 389 GLU E C   1 
ATOM   17302 O O   . GLU E 1 389 ? 45.536  70.135  27.177  1.00 25.51  ? 389 GLU E O   1 
ATOM   17303 C CB  . GLU E 1 389 ? 43.995  70.659  24.776  1.00 31.95  ? 389 GLU E CB  1 
ATOM   17304 C CG  . GLU E 1 389 ? 43.384  71.145  23.459  1.00 30.98  ? 389 GLU E CG  1 
ATOM   17305 C CD  . GLU E 1 389 ? 44.066  70.702  22.178  1.00 30.00  ? 389 GLU E CD  1 
ATOM   17306 O OE1 . GLU E 1 389 ? 43.643  71.306  21.183  1.00 31.56  ? 389 GLU E OE1 1 
ATOM   17307 O OE2 . GLU E 1 389 ? 44.931  69.792  22.128  1.00 26.34  ? 389 GLU E OE2 1 
ATOM   17308 N N   . TYR E 1 390 ? 46.108  72.311  27.403  1.00 25.16  ? 390 TYR E N   1 
ATOM   17309 C CA  . TYR E 1 390 ? 46.884  72.115  28.619  1.00 27.49  ? 390 TYR E CA  1 
ATOM   17310 C C   . TYR E 1 390 ? 46.218  71.104  29.547  1.00 28.31  ? 390 TYR E C   1 
ATOM   17311 O O   . TYR E 1 390 ? 46.863  70.128  29.925  1.00 31.53  ? 390 TYR E O   1 
ATOM   17312 C CB  . TYR E 1 390 ? 47.149  73.398  29.413  1.00 26.26  ? 390 TYR E CB  1 
ATOM   17313 C CG  . TYR E 1 390 ? 47.824  74.519  28.628  1.00 27.14  ? 390 TYR E CG  1 
ATOM   17314 C CD1 . TYR E 1 390 ? 49.208  74.587  28.485  1.00 24.98  ? 390 TYR E CD1 1 
ATOM   17315 C CD2 . TYR E 1 390 ? 47.064  75.553  28.086  1.00 28.42  ? 390 TYR E CD2 1 
ATOM   17316 C CE1 . TYR E 1 390 ? 49.804  75.635  27.794  1.00 25.54  ? 390 TYR E CE1 1 
ATOM   17317 C CE2 . TYR E 1 390 ? 47.648  76.609  27.409  1.00 28.48  ? 390 TYR E CE2 1 
ATOM   17318 C CZ  . TYR E 1 390 ? 49.022  76.648  27.264  1.00 26.94  ? 390 TYR E CZ  1 
ATOM   17319 O OH  . TYR E 1 390 ? 49.544  77.683  26.544  1.00 31.56  ? 390 TYR E OH  1 
ATOM   17320 N N   . ASP E 1 391 ? 44.934  71.336  29.891  1.00 30.07  ? 391 ASP E N   1 
ATOM   17321 C CA  . ASP E 1 391 ? 44.204  70.528  30.866  1.00 26.26  ? 391 ASP E CA  1 
ATOM   17322 C C   . ASP E 1 391 ? 44.269  69.049  30.492  1.00 24.70  ? 391 ASP E C   1 
ATOM   17323 O O   . ASP E 1 391 ? 44.248  68.229  31.388  1.00 24.99  ? 391 ASP E O   1 
ATOM   17324 C CB  . ASP E 1 391 ? 42.768  70.983  31.064  1.00 25.17  ? 391 ASP E CB  1 
ATOM   17325 C CG  . ASP E 1 391 ? 42.563  72.377  31.645  1.00 29.81  ? 391 ASP E CG  1 
ATOM   17326 O OD1 . ASP E 1 391 ? 43.589  73.023  32.029  1.00 30.72  ? 391 ASP E OD1 1 
ATOM   17327 O OD2 . ASP E 1 391 ? 41.372  72.816  31.708  1.00 30.99  ? 391 ASP E OD2 1 
ATOM   17328 N N   . PHE E 1 392 ? 44.363  68.718  29.190  1.00 24.63  ? 392 PHE E N   1 
ATOM   17329 C CA  . PHE E 1 392 ? 44.340  67.339  28.719  1.00 23.42  ? 392 PHE E CA  1 
ATOM   17330 C C   . PHE E 1 392 ? 45.701  66.688  28.965  1.00 23.21  ? 392 PHE E C   1 
ATOM   17331 O O   . PHE E 1 392 ? 45.796  65.467  28.960  1.00 22.76  ? 392 PHE E O   1 
ATOM   17332 C CB  . PHE E 1 392 ? 43.958  67.246  27.230  1.00 24.24  ? 392 PHE E CB  1 
ATOM   17333 C CG  . PHE E 1 392 ? 43.689  65.824  26.740  1.00 23.76  ? 392 PHE E CG  1 
ATOM   17334 C CD1 . PHE E 1 392 ? 42.499  65.170  27.066  1.00 23.64  ? 392 PHE E CD1 1 
ATOM   17335 C CD2 . PHE E 1 392 ? 44.634  65.130  25.998  1.00 22.00  ? 392 PHE E CD2 1 
ATOM   17336 C CE1 . PHE E 1 392 ? 42.248  63.874  26.644  1.00 23.02  ? 392 PHE E CE1 1 
ATOM   17337 C CE2 . PHE E 1 392 ? 44.392  63.824  25.592  1.00 23.61  ? 392 PHE E CE2 1 
ATOM   17338 C CZ  . PHE E 1 392 ? 43.200  63.195  25.912  1.00 24.73  ? 392 PHE E CZ  1 
ATOM   17339 N N   . TYR E 1 393 ? 46.759  67.476  29.191  1.00 24.32  ? 393 TYR E N   1 
ATOM   17340 C CA  . TYR E 1 393 ? 48.086  66.897  29.409  1.00 26.28  ? 393 TYR E CA  1 
ATOM   17341 C C   . TYR E 1 393 ? 48.076  65.885  30.560  1.00 27.06  ? 393 TYR E C   1 
ATOM   17342 O O   . TYR E 1 393 ? 48.728  64.848  30.463  1.00 25.97  ? 393 TYR E O   1 
ATOM   17343 C CB  . TYR E 1 393 ? 49.158  67.954  29.661  1.00 25.93  ? 393 TYR E CB  1 
ATOM   17344 C CG  . TYR E 1 393 ? 49.554  68.800  28.452  1.00 28.14  ? 393 TYR E CG  1 
ATOM   17345 C CD1 . TYR E 1 393 ? 48.899  68.718  27.228  1.00 29.50  ? 393 TYR E CD1 1 
ATOM   17346 C CD2 . TYR E 1 393 ? 50.609  69.695  28.545  1.00 30.17  ? 393 TYR E CD2 1 
ATOM   17347 C CE1 . TYR E 1 393 ? 49.302  69.472  26.134  1.00 28.61  ? 393 TYR E CE1 1 
ATOM   17348 C CE2 . TYR E 1 393 ? 51.005  70.475  27.467  1.00 32.08  ? 393 TYR E CE2 1 
ATOM   17349 C CZ  . TYR E 1 393 ? 50.358  70.355  26.252  1.00 29.22  ? 393 TYR E CZ  1 
ATOM   17350 O OH  . TYR E 1 393 ? 50.764  71.151  25.221  1.00 27.84  ? 393 TYR E OH  1 
ATOM   17351 N N   . THR E 1 394 ? 47.302  66.164  31.624  1.00 25.10  ? 394 THR E N   1 
ATOM   17352 C CA  . THR E 1 394 ? 47.239  65.281  32.778  1.00 24.58  ? 394 THR E CA  1 
ATOM   17353 C C   . THR E 1 394 ? 46.599  63.945  32.396  1.00 24.61  ? 394 THR E C   1 
ATOM   17354 O O   . THR E 1 394 ? 46.851  62.938  33.054  1.00 25.10  ? 394 THR E O   1 
ATOM   17355 C CB  . THR E 1 394 ? 46.481  65.956  33.927  1.00 23.27  ? 394 THR E CB  1 
ATOM   17356 O OG1 . THR E 1 394 ? 47.026  67.235  34.228  1.00 19.31  ? 394 THR E OG1 1 
ATOM   17357 C CG2 . THR E 1 394 ? 46.571  65.151  35.204  1.00 23.13  ? 394 THR E CG2 1 
ATOM   17358 N N   . VAL E 1 395 ? 45.743  63.941  31.361  1.00 25.08  ? 395 VAL E N   1 
ATOM   17359 C CA  . VAL E 1 395 ? 45.086  62.723  30.907  1.00 23.00  ? 395 VAL E CA  1 
ATOM   17360 C C   . VAL E 1 395 ? 46.118  61.850  30.195  1.00 23.05  ? 395 VAL E C   1 
ATOM   17361 O O   . VAL E 1 395 ? 46.152  60.640  30.407  1.00 24.97  ? 395 VAL E O   1 
ATOM   17362 C CB  . VAL E 1 395 ? 43.840  62.929  30.024  1.00 23.26  ? 395 VAL E CB  1 
ATOM   17363 C CG1 . VAL E 1 395 ? 43.290  61.593  29.522  1.00 25.59  ? 395 VAL E CG1 1 
ATOM   17364 C CG2 . VAL E 1 395 ? 42.740  63.711  30.731  1.00 22.11  ? 395 VAL E CG2 1 
ATOM   17365 N N   . LEU E 1 396 ? 46.964  62.445  29.354  1.00 23.60  ? 396 LEU E N   1 
ATOM   17366 C CA  . LEU E 1 396 ? 48.044  61.694  28.714  1.00 25.01  ? 396 LEU E CA  1 
ATOM   17367 C C   . LEU E 1 396 ? 48.924  61.028  29.776  1.00 22.58  ? 396 LEU E C   1 
ATOM   17368 O O   . LEU E 1 396 ? 49.208  59.823  29.713  1.00 21.25  ? 396 LEU E O   1 
ATOM   17369 C CB  . LEU E 1 396 ? 48.831  62.635  27.798  1.00 26.12  ? 396 LEU E CB  1 
ATOM   17370 C CG  . LEU E 1 396 ? 48.064  63.164  26.571  1.00 28.03  ? 396 LEU E CG  1 
ATOM   17371 C CD1 . LEU E 1 396 ? 48.853  64.222  25.793  1.00 28.95  ? 396 LEU E CD1 1 
ATOM   17372 C CD2 . LEU E 1 396 ? 47.641  62.012  25.640  1.00 27.54  ? 396 LEU E CD2 1 
ATOM   17373 N N   . PHE E 1 397 ? 49.299  61.822  30.787  1.00 23.59  ? 397 PHE E N   1 
ATOM   17374 C CA  . PHE E 1 397 ? 50.050  61.349  31.944  1.00 23.18  ? 397 PHE E CA  1 
ATOM   17375 C C   . PHE E 1 397 ? 49.362  60.117  32.530  1.00 24.10  ? 397 PHE E C   1 
ATOM   17376 O O   . PHE E 1 397 ? 49.962  59.048  32.668  1.00 22.62  ? 397 PHE E O   1 
ATOM   17377 C CB  . PHE E 1 397 ? 50.169  62.540  32.895  1.00 24.48  ? 397 PHE E CB  1 
ATOM   17378 C CG  . PHE E 1 397 ? 51.151  62.397  34.056  1.00 28.08  ? 397 PHE E CG  1 
ATOM   17379 C CD1 . PHE E 1 397 ? 51.970  61.280  34.185  1.00 29.26  ? 397 PHE E CD1 1 
ATOM   17380 C CD2 . PHE E 1 397 ? 51.338  63.453  34.948  1.00 28.55  ? 397 PHE E CD2 1 
ATOM   17381 C CE1 . PHE E 1 397 ? 52.885  61.190  35.216  1.00 31.09  ? 397 PHE E CE1 1 
ATOM   17382 C CE2 . PHE E 1 397 ? 52.246  63.353  35.985  1.00 28.80  ? 397 PHE E CE2 1 
ATOM   17383 C CZ  . PHE E 1 397 ? 53.013  62.211  36.119  1.00 29.50  ? 397 PHE E CZ  1 
ATOM   17384 N N   . GLY E 1 398 ? 48.069  60.278  32.814  1.00 24.79  ? 398 GLY E N   1 
ATOM   17385 C CA  . GLY E 1 398 ? 47.267  59.222  33.395  1.00 24.99  ? 398 GLY E CA  1 
ATOM   17386 C C   . GLY E 1 398 ? 47.299  57.958  32.555  1.00 25.90  ? 398 GLY E C   1 
ATOM   17387 O O   . GLY E 1 398 ? 47.439  56.862  33.117  1.00 24.36  ? 398 GLY E O   1 
ATOM   17388 N N   . VAL E 1 399 ? 47.165  58.121  31.223  1.00 27.70  ? 399 VAL E N   1 
ATOM   17389 C CA  . VAL E 1 399 ? 47.175  56.985  30.304  1.00 27.75  ? 399 VAL E CA  1 
ATOM   17390 C C   . VAL E 1 399 ? 48.492  56.231  30.474  1.00 24.35  ? 399 VAL E C   1 
ATOM   17391 O O   . VAL E 1 399 ? 48.495  55.007  30.637  1.00 21.23  ? 399 VAL E O   1 
ATOM   17392 C CB  . VAL E 1 399 ? 46.916  57.377  28.830  1.00 29.51  ? 399 VAL E CB  1 
ATOM   17393 C CG1 . VAL E 1 399 ? 47.200  56.259  27.818  1.00 29.99  ? 399 VAL E CG1 1 
ATOM   17394 C CG2 . VAL E 1 399 ? 45.484  57.843  28.644  1.00 28.69  ? 399 VAL E CG2 1 
ATOM   17395 N N   . SER E 1 400 ? 49.608  56.971  30.480  1.00 23.90  ? 400 SER E N   1 
ATOM   17396 C CA  . SER E 1 400 ? 50.906  56.323  30.599  1.00 26.02  ? 400 SER E CA  1 
ATOM   17397 C C   . SER E 1 400 ? 50.983  55.575  31.921  1.00 25.32  ? 400 SER E C   1 
ATOM   17398 O O   . SER E 1 400 ? 51.432  54.441  31.988  1.00 24.85  ? 400 SER E O   1 
ATOM   17399 C CB  . SER E 1 400 ? 52.039  57.301  30.517  1.00 29.79  ? 400 SER E CB  1 
ATOM   17400 O OG  . SER E 1 400 ? 53.279  56.668  30.802  1.00 29.29  ? 400 SER E OG  1 
ATOM   17401 N N   . ARG E 1 401 ? 50.540  56.252  32.973  1.00 25.31  ? 401 ARG E N   1 
ATOM   17402 C CA  . ARG E 1 401 ? 50.835  55.841  34.329  1.00 25.56  ? 401 ARG E CA  1 
ATOM   17403 C C   . ARG E 1 401 ? 49.981  54.629  34.688  1.00 26.41  ? 401 ARG E C   1 
ATOM   17404 O O   . ARG E 1 401 ? 50.270  53.942  35.691  1.00 23.57  ? 401 ARG E O   1 
ATOM   17405 C CB  . ARG E 1 401 ? 50.732  57.096  35.196  1.00 26.22  ? 401 ARG E CB  1 
ATOM   17406 C CG  . ARG E 1 401 ? 51.335  56.987  36.577  1.00 31.15  ? 401 ARG E CG  1 
ATOM   17407 C CD  . ARG E 1 401 ? 52.783  56.478  36.678  1.00 33.77  ? 401 ARG E CD  1 
ATOM   17408 N NE  . ARG E 1 401 ? 53.854  57.449  36.448  1.00 30.11  ? 401 ARG E NE  1 
ATOM   17409 C CZ  . ARG E 1 401 ? 54.213  58.449  37.246  1.00 34.23  ? 401 ARG E CZ  1 
ATOM   17410 N NH1 . ARG E 1 401 ? 53.585  58.682  38.387  1.00 38.51  ? 401 ARG E NH1 1 
ATOM   17411 N NH2 . ARG E 1 401 ? 55.219  59.234  36.891  1.00 34.03  ? 401 ARG E NH2 1 
ATOM   17412 N N   . ALA E 1 402 ? 49.001  54.324  33.813  1.00 21.87  ? 402 ALA E N   1 
ATOM   17413 C CA  . ALA E 1 402 ? 48.222  53.109  33.987  1.00 22.77  ? 402 ALA E CA  1 
ATOM   17414 C C   . ALA E 1 402 ? 49.045  51.854  33.731  1.00 20.69  ? 402 ALA E C   1 
ATOM   17415 O O   . ALA E 1 402 ? 48.664  50.754  34.126  1.00 20.33  ? 402 ALA E O   1 
ATOM   17416 C CB  . ALA E 1 402 ? 47.036  53.108  33.072  1.00 24.91  ? 402 ALA E CB  1 
ATOM   17417 N N   . LEU E 1 403 ? 50.130  51.994  32.986  1.00 22.84  ? 403 LEU E N   1 
ATOM   17418 C CA  . LEU E 1 403 ? 50.997  50.859  32.712  1.00 22.41  ? 403 LEU E CA  1 
ATOM   17419 C C   . LEU E 1 403 ? 51.591  50.388  34.047  1.00 23.68  ? 403 LEU E C   1 
ATOM   17420 O O   . LEU E 1 403 ? 51.503  49.211  34.412  1.00 19.69  ? 403 LEU E O   1 
ATOM   17421 C CB  . LEU E 1 403 ? 52.029  51.368  31.713  1.00 21.51  ? 403 LEU E CB  1 
ATOM   17422 C CG  . LEU E 1 403 ? 51.483  51.739  30.326  1.00 21.50  ? 403 LEU E CG  1 
ATOM   17423 C CD1 . LEU E 1 403 ? 52.472  52.553  29.480  1.00 21.13  ? 403 LEU E CD1 1 
ATOM   17424 C CD2 . LEU E 1 403 ? 51.096  50.474  29.580  1.00 22.20  ? 403 LEU E CD2 1 
ATOM   17425 N N   . GLY E 1 404 ? 52.074  51.365  34.828  1.00 22.91  ? 404 GLY E N   1 
ATOM   17426 C CA  . GLY E 1 404 ? 52.686  51.084  36.114  1.00 23.63  ? 404 GLY E CA  1 
ATOM   17427 C C   . GLY E 1 404 ? 51.663  50.654  37.157  1.00 23.46  ? 404 GLY E C   1 
ATOM   17428 O O   . GLY E 1 404 ? 51.873  49.648  37.836  1.00 26.46  ? 404 GLY E O   1 
ATOM   17429 N N   . CYS E 1 405 ? 50.540  51.382  37.243  1.00 25.05  ? 405 CYS E N   1 
ATOM   17430 C CA  . CYS E 1 405 ? 49.509  51.085  38.232  1.00 23.82  ? 405 CYS E CA  1 
ATOM   17431 C C   . CYS E 1 405 ? 48.945  49.691  38.052  1.00 21.99  ? 405 CYS E C   1 
ATOM   17432 O O   . CYS E 1 405 ? 48.763  49.004  39.041  1.00 23.24  ? 405 CYS E O   1 
ATOM   17433 C CB  . CYS E 1 405 ? 48.391  52.108  38.231  1.00 24.59  ? 405 CYS E CB  1 
ATOM   17434 S SG  . CYS E 1 405 ? 48.991  53.718  38.784  1.00 25.29  ? 405 CYS E SG  1 
ATOM   17435 N N   . THR E 1 406 ? 48.695  49.291  36.807  1.00 23.49  ? 406 THR E N   1 
ATOM   17436 C CA  . THR E 1 406 ? 48.192  47.954  36.538  1.00 26.57  ? 406 THR E CA  1 
ATOM   17437 C C   . THR E 1 406 ? 49.227  46.916  36.952  1.00 28.50  ? 406 THR E C   1 
ATOM   17438 O O   . THR E 1 406 ? 48.864  45.862  37.500  1.00 28.92  ? 406 THR E O   1 
ATOM   17439 C CB  . THR E 1 406 ? 47.759  47.729  35.082  1.00 27.27  ? 406 THR E CB  1 
ATOM   17440 O OG1 . THR E 1 406 ? 48.770  48.187  34.182  1.00 25.22  ? 406 THR E OG1 1 
ATOM   17441 C CG2 . THR E 1 406 ? 46.402  48.357  34.807  1.00 26.69  ? 406 THR E CG2 1 
ATOM   17442 N N   . ALA E 1 407 ? 50.500  47.216  36.661  1.00 27.05  ? 407 ALA E N   1 
ATOM   17443 C CA  . ALA E 1 407 ? 51.531  46.221  36.855  1.00 25.37  ? 407 ALA E CA  1 
ATOM   17444 C C   . ALA E 1 407 ? 51.668  46.010  38.351  1.00 23.53  ? 407 ALA E C   1 
ATOM   17445 O O   . ALA E 1 407 ? 51.708  44.874  38.831  1.00 25.48  ? 407 ALA E O   1 
ATOM   17446 C CB  . ALA E 1 407 ? 52.820  46.647  36.200  1.00 27.51  ? 407 ALA E CB  1 
ATOM   17447 N N   . GLN E 1 408 ? 51.702  47.125  39.079  1.00 23.40  ? 408 GLN E N   1 
ATOM   17448 C CA  . GLN E 1 408 ? 51.875  47.076  40.520  1.00 22.98  ? 408 GLN E CA  1 
ATOM   17449 C C   . GLN E 1 408 ? 50.680  46.387  41.177  1.00 25.33  ? 408 GLN E C   1 
ATOM   17450 O O   . GLN E 1 408 ? 50.844  45.634  42.137  1.00 27.59  ? 408 GLN E O   1 
ATOM   17451 C CB  . GLN E 1 408 ? 51.996  48.476  41.103  1.00 23.32  ? 408 GLN E CB  1 
ATOM   17452 C CG  . GLN E 1 408 ? 53.305  49.190  40.803  1.00 23.35  ? 408 GLN E CG  1 
ATOM   17453 C CD  . GLN E 1 408 ? 53.390  50.546  41.461  1.00 24.10  ? 408 GLN E CD  1 
ATOM   17454 O OE1 . GLN E 1 408 ? 53.938  51.519  40.929  1.00 26.15  ? 408 GLN E OE1 1 
ATOM   17455 N NE2 . GLN E 1 408 ? 52.825  50.623  42.649  1.00 25.45  ? 408 GLN E NE2 1 
ATOM   17456 N N   . ALA E 1 409 ? 49.480  46.630  40.651  1.00 24.98  ? 409 ALA E N   1 
ATOM   17457 C CA  . ALA E 1 409 ? 48.282  46.041  41.225  1.00 28.46  ? 409 ALA E CA  1 
ATOM   17458 C C   . ALA E 1 409 ? 48.210  44.537  40.972  1.00 29.37  ? 409 ALA E C   1 
ATOM   17459 O O   . ALA E 1 409 ? 47.698  43.782  41.795  1.00 31.08  ? 409 ALA E O   1 
ATOM   17460 C CB  . ALA E 1 409 ? 47.075  46.750  40.667  1.00 29.65  ? 409 ALA E CB  1 
ATOM   17461 N N   . ILE E 1 410 ? 48.681  44.104  39.802  1.00 33.02  ? 410 ILE E N   1 
ATOM   17462 C CA  . ILE E 1 410 ? 48.686  42.691  39.453  1.00 32.11  ? 410 ILE E CA  1 
ATOM   17463 C C   . ILE E 1 410 ? 49.652  41.965  40.376  1.00 33.57  ? 410 ILE E C   1 
ATOM   17464 O O   . ILE E 1 410 ? 49.355  40.857  40.836  1.00 31.40  ? 410 ILE E O   1 
ATOM   17465 C CB  . ILE E 1 410 ? 49.034  42.480  37.968  1.00 29.07  ? 410 ILE E CB  1 
ATOM   17466 C CG1 . ILE E 1 410 ? 47.846  42.895  37.070  1.00 30.26  ? 410 ILE E CG1 1 
ATOM   17467 C CG2 . ILE E 1 410 ? 49.459  41.031  37.715  1.00 27.71  ? 410 ILE E CG2 1 
ATOM   17468 C CD1 . ILE E 1 410 ? 48.206  43.100  35.615  1.00 31.37  ? 410 ILE E CD1 1 
ATOM   17469 N N   . LEU E 1 411 ? 50.787  42.636  40.626  1.00 30.41  ? 411 LEU E N   1 
ATOM   17470 C CA  . LEU E 1 411 ? 51.886  42.059  41.380  1.00 30.89  ? 411 LEU E CA  1 
ATOM   17471 C C   . LEU E 1 411 ? 51.504  41.862  42.851  1.00 32.37  ? 411 LEU E C   1 
ATOM   17472 O O   . LEU E 1 411 ? 51.718  40.769  43.390  1.00 32.39  ? 411 LEU E O   1 
ATOM   17473 C CB  . LEU E 1 411 ? 53.140  42.932  41.200  1.00 29.09  ? 411 LEU E CB  1 
ATOM   17474 C CG  . LEU E 1 411 ? 53.863  42.800  39.845  1.00 27.51  ? 411 LEU E CG  1 
ATOM   17475 C CD1 . LEU E 1 411 ? 54.963  43.826  39.674  1.00 26.66  ? 411 LEU E CD1 1 
ATOM   17476 C CD2 . LEU E 1 411 ? 54.428  41.408  39.591  1.00 24.96  ? 411 LEU E CD2 1 
ATOM   17477 N N   . VAL E 1 412 ? 50.972  42.919  43.510  1.00 32.41  ? 412 VAL E N   1 
ATOM   17478 C CA  . VAL E 1 412 ? 50.808  42.903  44.959  1.00 28.57  ? 412 VAL E CA  1 
ATOM   17479 C C   . VAL E 1 412 ? 49.681  41.941  45.300  1.00 28.88  ? 412 VAL E C   1 
ATOM   17480 O O   . VAL E 1 412 ? 49.722  41.373  46.373  1.00 29.12  ? 412 VAL E O   1 
ATOM   17481 C CB  . VAL E 1 412 ? 50.575  44.255  45.639  1.00 27.91  ? 412 VAL E CB  1 
ATOM   17482 C CG1 . VAL E 1 412 ? 51.690  45.229  45.318  1.00 32.06  ? 412 VAL E CG1 1 
ATOM   17483 C CG2 . VAL E 1 412 ? 49.243  44.870  45.262  1.00 31.83  ? 412 VAL E CG2 1 
ATOM   17484 N N   . ARG E 1 413 ? 48.757  41.719  44.349  1.00 30.79  ? 413 ARG E N   1 
ATOM   17485 C CA  . ARG E 1 413 ? 47.674  40.748  44.488  1.00 33.82  ? 413 ARG E CA  1 
ATOM   17486 C C   . ARG E 1 413 ? 48.186  39.336  44.234  1.00 33.14  ? 413 ARG E C   1 
ATOM   17487 O O   . ARG E 1 413 ? 47.584  38.358  44.670  1.00 34.04  ? 413 ARG E O   1 
ATOM   17488 C CB  . ARG E 1 413 ? 46.490  41.088  43.566  1.00 30.85  ? 413 ARG E CB  1 
ATOM   17489 C CG  . ARG E 1 413 ? 45.904  42.470  43.851  1.00 31.47  ? 413 ARG E CG  1 
ATOM   17490 C CD  . ARG E 1 413 ? 44.700  42.466  44.768  1.00 31.12  ? 413 ARG E CD  1 
ATOM   17491 N NE  . ARG E 1 413 ? 44.952  41.714  45.996  1.00 31.68  ? 413 ARG E NE  1 
ATOM   17492 C CZ  . ARG E 1 413 ? 45.765  42.114  46.966  1.00 31.81  ? 413 ARG E CZ  1 
ATOM   17493 N NH1 . ARG E 1 413 ? 46.150  43.386  47.100  1.00 30.28  ? 413 ARG E NH1 1 
ATOM   17494 N NH2 . ARG E 1 413 ? 46.129  41.210  47.850  1.00 32.23  ? 413 ARG E NH2 1 
ATOM   17495 N N   . GLY E 1 414 ? 49.276  39.243  43.471  1.00 35.17  ? 414 GLY E N   1 
ATOM   17496 C CA  . GLY E 1 414 ? 49.992  37.991  43.351  1.00 34.49  ? 414 GLY E CA  1 
ATOM   17497 C C   . GLY E 1 414 ? 50.710  37.694  44.664  1.00 33.01  ? 414 GLY E C   1 
ATOM   17498 O O   . GLY E 1 414 ? 50.683  36.555  45.144  1.00 30.64  ? 414 GLY E O   1 
ATOM   17499 N N   . TYR E 1 415 ? 51.311  38.745  45.240  1.00 29.17  ? 415 TYR E N   1 
ATOM   17500 C CA  . TYR E 1 415 ? 52.036  38.596  46.492  1.00 34.36  ? 415 TYR E CA  1 
ATOM   17501 C C   . TYR E 1 415 ? 51.050  38.299  47.632  1.00 32.30  ? 415 TYR E C   1 
ATOM   17502 O O   . TYR E 1 415 ? 51.392  37.622  48.600  1.00 30.82  ? 415 TYR E O   1 
ATOM   17503 C CB  . TYR E 1 415 ? 52.886  39.809  46.893  1.00 30.77  ? 415 TYR E CB  1 
ATOM   17504 C CG  . TYR E 1 415 ? 53.969  40.290  45.940  1.00 29.57  ? 415 TYR E CG  1 
ATOM   17505 C CD1 . TYR E 1 415 ? 54.355  39.588  44.797  1.00 30.88  ? 415 TYR E CD1 1 
ATOM   17506 C CD2 . TYR E 1 415 ? 54.626  41.483  46.214  1.00 30.66  ? 415 TYR E CD2 1 
ATOM   17507 C CE1 . TYR E 1 415 ? 55.359  40.066  43.958  1.00 28.26  ? 415 TYR E CE1 1 
ATOM   17508 C CE2 . TYR E 1 415 ? 55.608  41.986  45.376  1.00 30.05  ? 415 TYR E CE2 1 
ATOM   17509 C CZ  . TYR E 1 415 ? 55.975  41.275  44.249  1.00 29.64  ? 415 TYR E CZ  1 
ATOM   17510 O OH  . TYR E 1 415 ? 56.973  41.836  43.515  1.00 30.18  ? 415 TYR E OH  1 
ATOM   17511 N N   . MET E 1 416 ? 49.824  38.814  47.510  1.00 30.07  ? 416 MET E N   1 
ATOM   17512 C CA  . MET E 1 416 ? 48.799  38.670  48.525  1.00 27.99  ? 416 MET E CA  1 
ATOM   17513 C C   . MET E 1 416 ? 49.208  39.512  49.718  1.00 28.57  ? 416 MET E C   1 
ATOM   17514 O O   . MET E 1 416 ? 49.101  39.058  50.841  1.00 28.91  ? 416 MET E O   1 
ATOM   17515 C CB  . MET E 1 416 ? 48.614  37.226  48.986  1.00 28.65  ? 416 MET E CB  1 
ATOM   17516 C CG  . MET E 1 416 ? 48.331  36.270  47.866  1.00 33.87  ? 416 MET E CG  1 
ATOM   17517 S SD  . MET E 1 416 ? 47.954  34.668  48.605  1.00 41.52  ? 416 MET E SD  1 
ATOM   17518 C CE  . MET E 1 416 ? 47.435  33.809  47.120  1.00 45.82  ? 416 MET E CE  1 
ATOM   17519 N N   . LEU E 1 417 ? 49.727  40.713  49.446  1.00 28.32  ? 417 LEU E N   1 
ATOM   17520 C CA  . LEU E 1 417 ? 49.920  41.697  50.487  1.00 27.52  ? 417 LEU E CA  1 
ATOM   17521 C C   . LEU E 1 417 ? 48.552  41.972  51.097  1.00 31.04  ? 417 LEU E C   1 
ATOM   17522 O O   . LEU E 1 417 ? 47.512  41.775  50.461  1.00 27.62  ? 417 LEU E O   1 
ATOM   17523 C CB  . LEU E 1 417 ? 50.572  42.958  49.923  1.00 28.37  ? 417 LEU E CB  1 
ATOM   17524 C CG  . LEU E 1 417 ? 51.962  42.793  49.284  1.00 27.45  ? 417 LEU E CG  1 
ATOM   17525 C CD1 . LEU E 1 417 ? 52.573  44.136  48.995  1.00 27.78  ? 417 LEU E CD1 1 
ATOM   17526 C CD2 . LEU E 1 417 ? 52.949  41.994  50.129  1.00 30.41  ? 417 LEU E CD2 1 
ATOM   17527 N N   . PRO E 1 418 ? 48.501  42.354  52.387  1.00 35.18  ? 418 PRO E N   1 
ATOM   17528 C CA  . PRO E 1 418 ? 47.223  42.599  53.063  1.00 33.60  ? 418 PRO E CA  1 
ATOM   17529 C C   . PRO E 1 418 ? 46.743  44.035  52.903  1.00 30.19  ? 418 PRO E C   1 
ATOM   17530 O O   . PRO E 1 418 ? 47.357  44.832  52.208  1.00 32.66  ? 418 PRO E O   1 
ATOM   17531 C CB  . PRO E 1 418 ? 47.563  42.239  54.510  1.00 34.10  ? 418 PRO E CB  1 
ATOM   17532 C CG  . PRO E 1 418 ? 48.995  42.742  54.643  1.00 38.54  ? 418 PRO E CG  1 
ATOM   17533 C CD  . PRO E 1 418 ? 49.662  42.502  53.275  1.00 35.31  ? 418 PRO E CD  1 
ATOM   17534 N N   . ILE E 1 419 ? 45.610  44.326  53.529  1.00 29.71  ? 419 ILE E N   1 
ATOM   17535 C CA  . ILE E 1 419 ? 44.981  45.629  53.437  1.00 29.94  ? 419 ILE E CA  1 
ATOM   17536 C C   . ILE E 1 419 ? 45.903  46.689  54.034  1.00 29.61  ? 419 ILE E C   1 
ATOM   17537 O O   . ILE E 1 419 ? 46.676  46.394  54.939  1.00 29.48  ? 419 ILE E O   1 
ATOM   17538 C CB  . ILE E 1 419 ? 43.622  45.574  54.151  1.00 31.81  ? 419 ILE E CB  1 
ATOM   17539 C CG1 . ILE E 1 419 ? 42.781  46.809  53.868  1.00 32.88  ? 419 ILE E CG1 1 
ATOM   17540 C CG2 . ILE E 1 419 ? 43.804  45.325  55.660  1.00 30.91  ? 419 ILE E CG2 1 
ATOM   17541 C CD1 . ILE E 1 419 ? 41.308  46.627  54.198  1.00 33.72  ? 419 ILE E CD1 1 
ATOM   17542 N N   . GLU E 1 420 ? 45.830  47.920  53.515  1.00 30.71  ? 420 GLU E N   1 
ATOM   17543 C CA  . GLU E 1 420 ? 46.654  49.017  54.012  1.00 30.14  ? 420 GLU E CA  1 
ATOM   17544 C C   . GLU E 1 420 ? 45.840  49.744  55.081  1.00 34.42  ? 420 GLU E C   1 
ATOM   17545 O O   . GLU E 1 420 ? 44.854  50.420  54.756  1.00 43.01  ? 420 GLU E O   1 
ATOM   17546 C CB  . GLU E 1 420 ? 47.193  49.878  52.862  1.00 25.70  ? 420 GLU E CB  1 
ATOM   17547 C CG  . GLU E 1 420 ? 47.741  51.250  53.242  1.00 24.48  ? 420 GLU E CG  1 
ATOM   17548 C CD  . GLU E 1 420 ? 48.322  52.087  52.101  1.00 28.43  ? 420 GLU E CD  1 
ATOM   17549 O OE1 . GLU E 1 420 ? 48.632  53.283  52.351  1.00 32.29  ? 420 GLU E OE1 1 
ATOM   17550 O OE2 . GLU E 1 420 ? 48.476  51.595  50.957  1.00 28.81  ? 420 GLU E OE2 1 
ATOM   17551 N N   . ARG E 1 421 ? 46.273  49.562  56.343  1.00 35.48  ? 421 ARG E N   1 
ATOM   17552 C CA  . ARG E 1 421 ? 45.594  50.053  57.540  1.00 35.97  ? 421 ARG E CA  1 
ATOM   17553 C C   . ARG E 1 421 ? 46.649  50.647  58.481  1.00 34.00  ? 421 ARG E C   1 
ATOM   17554 O O   . ARG E 1 421 ? 46.994  50.049  59.487  1.00 33.62  ? 421 ARG E O   1 
ATOM   17555 C CB  . ARG E 1 421 ? 44.734  48.974  58.232  1.00 33.24  ? 421 ARG E CB  1 
ATOM   17556 N N   . PRO E 1 422 ? 47.221  51.835  58.181  1.00 37.46  ? 422 PRO E N   1 
ATOM   17557 C CA  . PRO E 1 422 ? 48.084  52.546  59.127  1.00 38.19  ? 422 PRO E CA  1 
ATOM   17558 C C   . PRO E 1 422 ? 47.298  52.975  60.356  1.00 35.76  ? 422 PRO E C   1 
ATOM   17559 O O   . PRO E 1 422 ? 46.088  52.841  60.365  1.00 39.91  ? 422 PRO E O   1 
ATOM   17560 C CB  . PRO E 1 422 ? 48.554  53.783  58.330  1.00 38.27  ? 422 PRO E CB  1 
ATOM   17561 C CG  . PRO E 1 422 ? 47.432  53.996  57.332  1.00 35.62  ? 422 PRO E CG  1 
ATOM   17562 C CD  . PRO E 1 422 ? 47.042  52.591  56.928  1.00 35.84  ? 422 PRO E CD  1 
ATOM   17563 N N   . LYS E 1 423 ? 47.996  53.516  61.357  1.00 36.15  ? 423 LYS E N   1 
ATOM   17564 C CA  . LYS E 1 423 ? 47.367  54.008  62.566  1.00 37.29  ? 423 LYS E CA  1 
ATOM   17565 C C   . LYS E 1 423 ? 47.403  55.528  62.532  1.00 35.64  ? 423 LYS E C   1 
ATOM   17566 O O   . LYS E 1 423 ? 48.447  56.091  62.219  1.00 30.50  ? 423 LYS E O   1 
ATOM   17567 C CB  . LYS E 1 423 ? 48.126  53.488  63.790  1.00 44.80  ? 423 LYS E CB  1 
ATOM   17568 C CG  . LYS E 1 423 ? 47.679  54.036  65.153  1.00 48.08  ? 423 LYS E CG  1 
ATOM   17569 C CD  . LYS E 1 423 ? 46.207  53.847  65.538  1.00 47.52  ? 423 LYS E CD  1 
ATOM   17570 C CE  . LYS E 1 423 ? 45.870  54.519  66.853  1.00 44.63  ? 423 LYS E CE  1 
ATOM   17571 N NZ  . LYS E 1 423 ? 44.566  54.079  67.337  1.00 44.23  ? 423 LYS E NZ  1 
ATOM   17572 N N   . SER E 1 424 ? 46.260  56.172  62.840  1.00 34.40  ? 424 SER E N   1 
ATOM   17573 C CA  . SER E 1 424 ? 46.219  57.623  62.991  1.00 34.79  ? 424 SER E CA  1 
ATOM   17574 C C   . SER E 1 424 ? 46.405  57.991  64.467  1.00 34.76  ? 424 SER E C   1 
ATOM   17575 O O   . SER E 1 424 ? 46.255  57.145  65.353  1.00 33.00  ? 424 SER E O   1 
ATOM   17576 C CB  . SER E 1 424 ? 44.969  58.258  62.395  1.00 33.51  ? 424 SER E CB  1 
ATOM   17577 O OG  . SER E 1 424 ? 43.776  57.907  63.079  1.00 31.77  ? 424 SER E OG  1 
ATOM   17578 N N   . ILE E 1 425 ? 46.826  59.240  64.698  1.00 33.01  ? 425 ILE E N   1 
ATOM   17579 C CA  . ILE E 1 425 ? 47.159  59.716  66.033  1.00 35.53  ? 425 ILE E CA  1 
ATOM   17580 C C   . ILE E 1 425 ? 46.532  61.095  66.188  1.00 37.66  ? 425 ILE E C   1 
ATOM   17581 O O   . ILE E 1 425 ? 46.352  61.817  65.199  1.00 38.12  ? 425 ILE E O   1 
ATOM   17582 C CB  . ILE E 1 425 ? 48.688  59.758  66.307  1.00 31.26  ? 425 ILE E CB  1 
ATOM   17583 C CG1 . ILE E 1 425 ? 49.364  60.893  65.556  1.00 29.09  ? 425 ILE E CG1 1 
ATOM   17584 C CG2 . ILE E 1 425 ? 49.371  58.418  66.018  1.00 29.86  ? 425 ILE E CG2 1 
ATOM   17585 C CD1 . ILE E 1 425 ? 50.873  60.954  65.749  1.00 29.56  ? 425 ILE E CD1 1 
ATOM   17586 N N   . THR E 1 426 ? 46.278  61.459  67.450  1.00 35.67  ? 426 THR E N   1 
ATOM   17587 C CA  . THR E 1 426 ? 45.584  62.692  67.779  1.00 35.95  ? 426 THR E CA  1 
ATOM   17588 C C   . THR E 1 426 ? 46.580  63.771  68.200  1.00 34.58  ? 426 THR E C   1 
ATOM   17589 O O   . THR E 1 426 ? 47.578  63.520  68.871  1.00 32.62  ? 426 THR E O   1 
ATOM   17590 C CB  . THR E 1 426 ? 44.538  62.375  68.846  1.00 39.05  ? 426 THR E CB  1 
ATOM   17591 O OG1 . THR E 1 426 ? 45.095  61.665  69.951  1.00 36.64  ? 426 THR E OG1 1 
ATOM   17592 C CG2 . THR E 1 426 ? 43.468  61.443  68.305  1.00 39.71  ? 426 THR E CG2 1 
ATOM   17593 N N   . THR E 1 427 ? 46.327  64.990  67.743  1.00 31.24  ? 427 THR E N   1 
ATOM   17594 C CA  . THR E 1 427 ? 47.046  66.136  68.251  1.00 33.61  ? 427 THR E CA  1 
ATOM   17595 C C   . THR E 1 427 ? 46.954  66.138  69.786  1.00 37.18  ? 427 THR E C   1 
ATOM   17596 O O   . THR E 1 427 ? 47.915  66.490  70.454  1.00 39.59  ? 427 THR E O   1 
ATOM   17597 C CB  . THR E 1 427 ? 46.493  67.397  67.573  1.00 33.31  ? 427 THR E CB  1 
ATOM   17598 O OG1 . THR E 1 427 ? 46.733  67.241  66.172  1.00 35.05  ? 427 THR E OG1 1 
ATOM   17599 C CG2 . THR E 1 427 ? 47.139  68.686  68.045  1.00 31.32  ? 427 THR E CG2 1 
ATOM   17600 N N   . ARG E 1 428 ? 45.827  65.694  70.362  1.00 36.25  ? 428 ARG E N   1 
ATOM   17601 C CA  . ARG E 1 428 ? 45.652  65.687  71.806  1.00 33.72  ? 428 ARG E CA  1 
ATOM   17602 C C   . ARG E 1 428 ? 46.743  64.824  72.455  1.00 32.49  ? 428 ARG E C   1 
ATOM   17603 O O   . ARG E 1 428 ? 47.333  65.221  73.457  1.00 29.71  ? 428 ARG E O   1 
ATOM   17604 C CB  . ARG E 1 428 ? 44.244  65.195  72.189  1.00 34.75  ? 428 ARG E CB  1 
ATOM   17605 C CG  . ARG E 1 428 ? 43.941  65.148  73.686  1.00 33.16  ? 428 ARG E CG  1 
ATOM   17606 C CD  . ARG E 1 428 ? 43.108  63.953  74.086  1.00 34.28  ? 428 ARG E CD  1 
ATOM   17607 N NE  . ARG E 1 428 ? 43.701  62.625  73.880  1.00 37.38  ? 428 ARG E NE  1 
ATOM   17608 C CZ  . ARG E 1 428 ? 44.699  62.076  74.598  1.00 35.12  ? 428 ARG E CZ  1 
ATOM   17609 N NH1 . ARG E 1 428 ? 45.105  60.838  74.358  1.00 36.47  ? 428 ARG E NH1 1 
ATOM   17610 N NH2 . ARG E 1 428 ? 45.280  62.744  75.566  1.00 33.24  ? 428 ARG E NH2 1 
ATOM   17611 N N   . TRP E 1 429 ? 46.986  63.636  71.894  1.00 31.51  ? 429 TRP E N   1 
ATOM   17612 C CA  . TRP E 1 429 ? 47.999  62.725  72.396  1.00 33.45  ? 429 TRP E CA  1 
ATOM   17613 C C   . TRP E 1 429 ? 49.416  63.278  72.208  1.00 32.84  ? 429 TRP E C   1 
ATOM   17614 O O   . TRP E 1 429 ? 50.263  63.145  73.081  1.00 32.44  ? 429 TRP E O   1 
ATOM   17615 C CB  . TRP E 1 429 ? 47.873  61.362  71.704  1.00 37.09  ? 429 TRP E CB  1 
ATOM   17616 C CG  . TRP E 1 429 ? 48.973  60.427  72.121  1.00 44.49  ? 429 TRP E CG  1 
ATOM   17617 C CD1 . TRP E 1 429 ? 49.160  59.893  73.362  1.00 43.19  ? 429 TRP E CD1 1 
ATOM   17618 C CD2 . TRP E 1 429 ? 50.073  59.976  71.310  1.00 47.25  ? 429 TRP E CD2 1 
ATOM   17619 N NE1 . TRP E 1 429 ? 50.275  59.106  73.370  1.00 46.47  ? 429 TRP E NE1 1 
ATOM   17620 C CE2 . TRP E 1 429 ? 50.856  59.132  72.128  1.00 50.95  ? 429 TRP E CE2 1 
ATOM   17621 C CE3 . TRP E 1 429 ? 50.469  60.192  69.988  1.00 43.95  ? 429 TRP E CE3 1 
ATOM   17622 C CZ2 . TRP E 1 429 ? 52.013  58.508  71.659  1.00 47.24  ? 429 TRP E CZ2 1 
ATOM   17623 C CZ3 . TRP E 1 429 ? 51.609  59.570  69.529  1.00 44.87  ? 429 TRP E CZ3 1 
ATOM   17624 C CH2 . TRP E 1 429 ? 52.372  58.745  70.356  1.00 43.09  ? 429 TRP E CH2 1 
ATOM   17625 N N   . VAL E 1 430 ? 49.668  63.882  71.053  1.00 29.41  ? 430 VAL E N   1 
ATOM   17626 C CA  . VAL E 1 430 ? 50.963  64.442  70.737  1.00 30.02  ? 430 VAL E CA  1 
ATOM   17627 C C   . VAL E 1 430 ? 51.266  65.564  71.721  1.00 33.33  ? 430 VAL E C   1 
ATOM   17628 O O   . VAL E 1 430 ? 52.360  65.605  72.261  1.00 36.05  ? 430 VAL E O   1 
ATOM   17629 C CB  . VAL E 1 430 ? 50.960  64.928  69.270  1.00 31.09  ? 430 VAL E CB  1 
ATOM   17630 C CG1 . VAL E 1 430 ? 52.144  65.828  68.924  1.00 30.45  ? 430 VAL E CG1 1 
ATOM   17631 C CG2 . VAL E 1 430 ? 50.865  63.766  68.285  1.00 29.30  ? 430 VAL E CG2 1 
ATOM   17632 N N   . LYS E 1 431 ? 50.304  66.463  71.966  1.00 37.21  ? 431 LYS E N   1 
ATOM   17633 C CA  . LYS E 1 431 ? 50.553  67.630  72.808  1.00 40.93  ? 431 LYS E CA  1 
ATOM   17634 C C   . LYS E 1 431 ? 50.825  67.187  74.247  1.00 40.22  ? 431 LYS E C   1 
ATOM   17635 O O   . LYS E 1 431 ? 51.476  67.906  74.994  1.00 36.22  ? 431 LYS E O   1 
ATOM   17636 C CB  . LYS E 1 431 ? 49.403  68.634  72.944  1.00 41.94  ? 431 LYS E CB  1 
ATOM   17637 C CG  . LYS E 1 431 ? 48.968  69.329  71.690  1.00 53.04  ? 431 LYS E CG  1 
ATOM   17638 C CD  . LYS E 1 431 ? 47.840  70.347  71.867  1.00 65.56  ? 431 LYS E CD  1 
ATOM   17639 C CE  . LYS E 1 431 ? 48.371  71.652  72.377  1.00 84.86  ? 431 LYS E CE  1 
ATOM   17640 N NZ  . LYS E 1 431 ? 47.335  72.680  72.501  1.00 93.38  ? 431 LYS E NZ  1 
ATOM   17641 N N   . GLU E 1 432 ? 50.266  66.037  74.632  1.00 40.76  ? 432 GLU E N   1 
ATOM   17642 C CA  . GLU E 1 432 ? 50.417  65.505  75.972  1.00 48.00  ? 432 GLU E CA  1 
ATOM   17643 C C   . GLU E 1 432 ? 51.830  64.936  76.094  1.00 48.63  ? 432 GLU E C   1 
ATOM   17644 O O   . GLU E 1 432 ? 52.568  65.351  76.989  1.00 51.78  ? 432 GLU E O   1 
ATOM   17645 C CB  . GLU E 1 432 ? 49.309  64.484  76.276  1.00 52.67  ? 432 GLU E CB  1 
ATOM   17646 C CG  . GLU E 1 432 ? 49.466  63.783  77.627  1.00 60.32  ? 432 GLU E CG  1 
ATOM   17647 C CD  . GLU E 1 432 ? 48.482  62.664  77.972  1.00 65.42  ? 432 GLU E CD  1 
ATOM   17648 O OE1 . GLU E 1 432 ? 47.992  62.721  79.123  1.00 77.30  ? 432 GLU E OE1 1 
ATOM   17649 O OE2 . GLU E 1 432 ? 48.184  61.755  77.158  1.00 50.19  ? 432 GLU E OE2 1 
ATOM   17650 N N   . VAL E 1 433 ? 52.209  64.062  75.138  1.00 45.37  ? 433 VAL E N   1 
ATOM   17651 C CA  . VAL E 1 433 ? 53.300  63.101  75.285  1.00 40.65  ? 433 VAL E CA  1 
ATOM   17652 C C   . VAL E 1 433 ? 54.606  63.537  74.621  1.00 36.93  ? 433 VAL E C   1 
ATOM   17653 O O   . VAL E 1 433 ? 55.638  62.944  74.920  1.00 33.93  ? 433 VAL E O   1 
ATOM   17654 C CB  . VAL E 1 433 ? 52.820  61.755  74.723  1.00 36.83  ? 433 VAL E CB  1 
ATOM   17655 C CG1 . VAL E 1 433 ? 53.919  60.737  74.582  1.00 36.37  ? 433 VAL E CG1 1 
ATOM   17656 C CG2 . VAL E 1 433 ? 51.749  61.188  75.623  1.00 45.55  ? 433 VAL E CG2 1 
ATOM   17657 N N   . ALA E 1 434 ? 54.562  64.549  73.746  1.00 37.40  ? 434 ALA E N   1 
ATOM   17658 C CA  . ALA E 1 434 ? 55.703  64.910  72.919  1.00 43.94  ? 434 ALA E CA  1 
ATOM   17659 C C   . ALA E 1 434 ? 56.944  65.138  73.776  1.00 46.17  ? 434 ALA E C   1 
ATOM   17660 O O   . ALA E 1 434 ? 57.995  64.568  73.481  1.00 44.97  ? 434 ALA E O   1 
ATOM   17661 C CB  . ALA E 1 434 ? 55.410  66.141  72.080  1.00 46.13  ? 434 ALA E CB  1 
ATOM   17662 N N   . GLU E 1 435 ? 56.806  65.950  74.836  1.00 47.88  ? 435 GLU E N   1 
ATOM   17663 C CA  . GLU E 1 435 ? 57.943  66.307  75.676  1.00 50.44  ? 435 GLU E CA  1 
ATOM   17664 C C   . GLU E 1 435 ? 58.629  65.059  76.242  1.00 48.83  ? 435 GLU E C   1 
ATOM   17665 O O   . GLU E 1 435 ? 59.828  65.091  76.496  1.00 42.80  ? 435 GLU E O   1 
ATOM   17666 C CB  . GLU E 1 435 ? 57.589  67.274  76.805  1.00 51.70  ? 435 GLU E CB  1 
ATOM   17667 C CG  . GLU E 1 435 ? 57.783  68.741  76.420  1.00 61.32  ? 435 GLU E CG  1 
ATOM   17668 C CD  . GLU E 1 435 ? 59.198  69.326  76.271  1.00 63.99  ? 435 GLU E CD  1 
ATOM   17669 O OE1 . GLU E 1 435 ? 60.233  68.614  76.316  1.00 67.81  ? 435 GLU E OE1 1 
ATOM   17670 O OE2 . GLU E 1 435 ? 59.267  70.568  76.104  1.00 57.56  ? 435 GLU E OE2 1 
ATOM   17671 N N   . SER E 1 436 ? 57.890  63.953  76.396  1.00 44.02  ? 436 SER E N   1 
ATOM   17672 C CA  . SER E 1 436 ? 58.423  62.774  77.055  1.00 42.55  ? 436 SER E CA  1 
ATOM   17673 C C   . SER E 1 436 ? 58.905  61.732  76.055  1.00 39.58  ? 436 SER E C   1 
ATOM   17674 O O   . SER E 1 436 ? 59.306  60.632  76.430  1.00 44.61  ? 436 SER E O   1 
ATOM   17675 C CB  . SER E 1 436 ? 57.393  62.223  77.985  1.00 47.07  ? 436 SER E CB  1 
ATOM   17676 O OG  . SER E 1 436 ? 57.078  63.188  78.991  1.00 47.28  ? 436 SER E OG  1 
ATOM   17677 N N   . LEU E 1 437 ? 58.888  62.092  74.773  1.00 38.62  ? 437 LEU E N   1 
ATOM   17678 C CA  . LEU E 1 437 ? 59.328  61.190  73.725  1.00 34.91  ? 437 LEU E CA  1 
ATOM   17679 C C   . LEU E 1 437 ? 60.828  61.367  73.535  1.00 31.15  ? 437 LEU E C   1 
ATOM   17680 O O   . LEU E 1 437 ? 61.349  62.473  73.707  1.00 28.51  ? 437 LEU E O   1 
ATOM   17681 C CB  . LEU E 1 437 ? 58.541  61.505  72.449  1.00 41.73  ? 437 LEU E CB  1 
ATOM   17682 C CG  . LEU E 1 437 ? 57.443  60.515  72.015  1.00 42.41  ? 437 LEU E CG  1 
ATOM   17683 C CD1 . LEU E 1 437 ? 56.810  59.741  73.141  1.00 40.96  ? 437 LEU E CD1 1 
ATOM   17684 C CD2 . LEU E 1 437 ? 56.356  61.232  71.237  1.00 40.76  ? 437 LEU E CD2 1 
ATOM   17685 N N   . PRO E 1 438 ? 61.563  60.296  73.159  1.00 30.14  ? 438 PRO E N   1 
ATOM   17686 C CA  . PRO E 1 438 ? 62.974  60.439  72.779  1.00 32.85  ? 438 PRO E CA  1 
ATOM   17687 C C   . PRO E 1 438 ? 63.080  61.156  71.435  1.00 39.77  ? 438 PRO E C   1 
ATOM   17688 O O   . PRO E 1 438 ? 62.133  61.128  70.641  1.00 36.16  ? 438 PRO E O   1 
ATOM   17689 C CB  . PRO E 1 438 ? 63.471  59.001  72.691  1.00 30.83  ? 438 PRO E CB  1 
ATOM   17690 C CG  . PRO E 1 438 ? 62.219  58.217  72.328  1.00 31.28  ? 438 PRO E CG  1 
ATOM   17691 C CD  . PRO E 1 438 ? 61.060  58.916  73.032  1.00 29.04  ? 438 PRO E CD  1 
ATOM   17692 N N   . VAL E 1 439 ? 64.235  61.792  71.181  1.00 44.37  ? 439 VAL E N   1 
ATOM   17693 C CA  . VAL E 1 439 ? 64.502  62.381  69.871  1.00 46.40  ? 439 VAL E CA  1 
ATOM   17694 C C   . VAL E 1 439 ? 65.154  61.326  68.973  1.00 42.28  ? 439 VAL E C   1 
ATOM   17695 O O   . VAL E 1 439 ? 65.933  60.506  69.437  1.00 36.12  ? 439 VAL E O   1 
ATOM   17696 C CB  . VAL E 1 439 ? 65.289  63.711  69.907  1.00 46.29  ? 439 VAL E CB  1 
ATOM   17697 C CG1 . VAL E 1 439 ? 65.575  64.179  71.324  1.00 50.68  ? 439 VAL E CG1 1 
ATOM   17698 C CG2 . VAL E 1 439 ? 66.545  63.683  69.041  1.00 47.83  ? 439 VAL E CG2 1 
ATOM   17699 N N   . ALA E 1 440 ? 64.793  61.347  67.683  1.00 49.05  ? 440 ALA E N   1 
ATOM   17700 C CA  . ALA E 1 440 ? 65.236  60.359  66.701  1.00 53.79  ? 440 ALA E CA  1 
ATOM   17701 C C   . ALA E 1 440 ? 66.756  60.386  66.534  1.00 55.34  ? 440 ALA E C   1 
ATOM   17702 O O   . ALA E 1 440 ? 67.326  61.449  66.305  1.00 51.24  ? 440 ALA E O   1 
ATOM   17703 C CB  . ALA E 1 440 ? 64.561  60.613  65.372  1.00 53.39  ? 440 ALA E CB  1 
ATOM   17704 N N   . GLY E 1 441 ? 67.372  59.194  66.616  1.00 58.48  ? 441 GLY E N   1 
ATOM   17705 C CA  . GLY E 1 441 ? 68.815  59.032  66.722  1.00 65.23  ? 441 GLY E CA  1 
ATOM   17706 C C   . GLY E 1 441 ? 69.158  57.783  67.531  1.00 70.99  ? 441 GLY E C   1 
ATOM   17707 O O   . GLY E 1 441 ? 69.691  57.937  68.666  1.00 56.67  ? 441 GLY E O   1 
ATOM   17708 N N   . MET F 1 1   ? -9.106  91.045  26.194  1.00 40.23  ? 1   MET F N   1 
ATOM   17709 C CA  . MET F 1 1   ? -7.887  91.882  26.323  1.00 41.90  ? 1   MET F CA  1 
ATOM   17710 C C   . MET F 1 1   ? -8.136  93.236  25.656  1.00 39.24  ? 1   MET F C   1 
ATOM   17711 O O   . MET F 1 1   ? -8.525  93.265  24.492  1.00 36.67  ? 1   MET F O   1 
ATOM   17712 C CB  . MET F 1 1   ? -6.738  91.098  25.676  1.00 46.15  ? 1   MET F CB  1 
ATOM   17713 C CG  . MET F 1 1   ? -5.341  91.638  25.894  1.00 51.07  ? 1   MET F CG  1 
ATOM   17714 S SD  . MET F 1 1   ? -4.111  90.675  24.975  1.00 56.48  ? 1   MET F SD  1 
ATOM   17715 C CE  . MET F 1 1   ? -2.710  91.319  25.896  1.00 55.08  ? 1   MET F CE  1 
ATOM   17716 N N   . LYS F 1 2   ? -7.907  94.351  26.369  1.00 40.85  ? 2   LYS F N   1 
ATOM   17717 C CA  . LYS F 1 2   ? -8.065  95.680  25.776  1.00 49.59  ? 2   LYS F CA  1 
ATOM   17718 C C   . LYS F 1 2   ? -7.159  95.825  24.546  1.00 48.77  ? 2   LYS F C   1 
ATOM   17719 O O   . LYS F 1 2   ? -7.580  96.328  23.504  1.00 43.08  ? 2   LYS F O   1 
ATOM   17720 C CB  . LYS F 1 2   ? -7.737  96.877  26.683  1.00 59.63  ? 2   LYS F CB  1 
ATOM   17721 C CG  . LYS F 1 2   ? -8.512  96.953  27.997  1.00 79.09  ? 2   LYS F CG  1 
ATOM   17722 C CD  . LYS F 1 2   ? -9.982  97.361  27.892  1.00 91.53  ? 2   LYS F CD  1 
ATOM   17723 C CE  . LYS F 1 2   ? -10.793 97.007  29.119  1.00 90.26  ? 2   LYS F CE  1 
ATOM   17724 N NZ  . LYS F 1 2   ? -12.126 97.624  29.136  1.00 87.14  ? 2   LYS F NZ  1 
ATOM   17725 N N   . LEU F 1 3   ? -5.907  95.370  24.669  1.00 46.01  ? 3   LEU F N   1 
ATOM   17726 C CA  . LEU F 1 3   ? -4.918  95.521  23.613  1.00 45.43  ? 3   LEU F CA  1 
ATOM   17727 C C   . LEU F 1 3   ? -5.469  95.049  22.262  1.00 41.37  ? 3   LEU F C   1 
ATOM   17728 O O   . LEU F 1 3   ? -5.319  95.714  21.234  1.00 31.98  ? 3   LEU F O   1 
ATOM   17729 C CB  . LEU F 1 3   ? -3.644  94.755  23.980  1.00 41.88  ? 3   LEU F CB  1 
ATOM   17730 C CG  . LEU F 1 3   ? -2.555  94.778  22.904  1.00 37.72  ? 3   LEU F CG  1 
ATOM   17731 C CD1 . LEU F 1 3   ? -2.290  96.202  22.454  1.00 35.29  ? 3   LEU F CD1 1 
ATOM   17732 C CD2 . LEU F 1 3   ? -1.275  94.134  23.391  1.00 39.16  ? 3   LEU F CD2 1 
ATOM   17733 N N   . LYS F 1 4   ? -6.093  93.872  22.264  1.00 39.82  ? 4   LYS F N   1 
ATOM   17734 C CA  . LYS F 1 4   ? -6.601  93.323  21.028  1.00 37.19  ? 4   LYS F CA  1 
ATOM   17735 C C   . LYS F 1 4   ? -7.817  94.117  20.560  1.00 36.37  ? 4   LYS F C   1 
ATOM   17736 O O   . LYS F 1 4   ? -7.912  94.419  19.383  1.00 37.03  ? 4   LYS F O   1 
ATOM   17737 C CB  . LYS F 1 4   ? -6.889  91.838  21.212  1.00 39.06  ? 4   LYS F CB  1 
ATOM   17738 C CG  . LYS F 1 4   ? -7.426  91.197  19.961  1.00 41.99  ? 4   LYS F CG  1 
ATOM   17739 C CD  . LYS F 1 4   ? -7.278  89.687  19.876  1.00 43.72  ? 4   LYS F CD  1 
ATOM   17740 C CE  . LYS F 1 4   ? -8.144  89.226  18.762  1.00 45.52  ? 4   LYS F CE  1 
ATOM   17741 N NZ  . LYS F 1 4   ? -7.461  88.215  17.964  1.00 48.93  ? 4   LYS F NZ  1 
ATOM   17742 N N   . GLU F 1 5   ? -8.742  94.448  21.470  1.00 38.32  ? 5   GLU F N   1 
ATOM   17743 C CA  . GLU F 1 5   ? -9.960  95.163  21.097  1.00 40.43  ? 5   GLU F CA  1 
ATOM   17744 C C   . GLU F 1 5   ? -9.567  96.440  20.358  1.00 36.73  ? 5   GLU F C   1 
ATOM   17745 O O   . GLU F 1 5   ? -10.132 96.770  19.325  1.00 36.17  ? 5   GLU F O   1 
ATOM   17746 C CB  . GLU F 1 5   ? -10.831 95.534  22.305  1.00 41.28  ? 5   GLU F CB  1 
ATOM   17747 C CG  . GLU F 1 5   ? -11.586 94.377  22.956  1.00 43.56  ? 5   GLU F CG  1 
ATOM   17748 C CD  . GLU F 1 5   ? -12.044 94.675  24.378  1.00 49.21  ? 5   GLU F CD  1 
ATOM   17749 O OE1 . GLU F 1 5   ? -12.473 93.732  25.066  1.00 51.65  ? 5   GLU F OE1 1 
ATOM   17750 O OE2 . GLU F 1 5   ? -11.961 95.836  24.831  1.00 48.95  ? 5   GLU F OE2 1 
ATOM   17751 N N   . ARG F 1 6   ? -8.551  97.112  20.893  1.00 34.61  ? 6   ARG F N   1 
ATOM   17752 C CA  . ARG F 1 6   ? -8.045  98.359  20.368  1.00 35.11  ? 6   ARG F CA  1 
ATOM   17753 C C   . ARG F 1 6   ? -7.340  98.167  19.024  1.00 36.77  ? 6   ARG F C   1 
ATOM   17754 O O   . ARG F 1 6   ? -7.443  98.980  18.103  1.00 36.51  ? 6   ARG F O   1 
ATOM   17755 C CB  . ARG F 1 6   ? -7.103  98.814  21.477  1.00 39.83  ? 6   ARG F CB  1 
ATOM   17756 C CG  . ARG F 1 6   ? -6.942  100.315 21.532  1.00 44.14  ? 6   ARG F CG  1 
ATOM   17757 C CD  . ARG F 1 6   ? -8.153  100.981 22.145  1.00 42.57  ? 6   ARG F CD  1 
ATOM   17758 N NE  . ARG F 1 6   ? -8.084  102.282 21.473  1.00 44.25  ? 6   ARG F NE  1 
ATOM   17759 C CZ  . ARG F 1 6   ? -8.741  102.568 20.358  1.00 41.78  ? 6   ARG F CZ  1 
ATOM   17760 N NH1 . ARG F 1 6   ? -9.770  101.808 20.000  1.00 42.59  ? 6   ARG F NH1 1 
ATOM   17761 N NH2 . ARG F 1 6   ? -8.401  103.633 19.646  1.00 37.71  ? 6   ARG F NH2 1 
ATOM   17762 N N   . LEU F 1 7   ? -6.595  97.078  18.891  1.00 36.38  ? 7   LEU F N   1 
ATOM   17763 C CA  . LEU F 1 7   ? -5.906  96.836  17.638  1.00 35.81  ? 7   LEU F CA  1 
ATOM   17764 C C   . LEU F 1 7   ? -6.912  96.556  16.515  1.00 34.48  ? 7   LEU F C   1 
ATOM   17765 O O   . LEU F 1 7   ? -6.655  96.879  15.344  1.00 33.29  ? 7   LEU F O   1 
ATOM   17766 C CB  . LEU F 1 7   ? -4.890  95.709  17.843  1.00 35.72  ? 7   LEU F CB  1 
ATOM   17767 C CG  . LEU F 1 7   ? -3.589  96.101  18.545  1.00 34.73  ? 7   LEU F CG  1 
ATOM   17768 C CD1 . LEU F 1 7   ? -2.707  94.886  18.726  1.00 33.87  ? 7   LEU F CD1 1 
ATOM   17769 C CD2 . LEU F 1 7   ? -2.824  97.204  17.807  1.00 37.55  ? 7   LEU F CD2 1 
ATOM   17770 N N   . ALA F 1 8   ? -8.057  95.964  16.881  1.00 31.77  ? 8   ALA F N   1 
ATOM   17771 C CA  . ALA F 1 8   ? -9.067  95.557  15.914  1.00 32.72  ? 8   ALA F CA  1 
ATOM   17772 C C   . ALA F 1 8   ? -9.709  96.767  15.239  1.00 36.22  ? 8   ALA F C   1 
ATOM   17773 O O   . ALA F 1 8   ? -10.179 96.632  14.116  1.00 34.04  ? 8   ALA F O   1 
ATOM   17774 C CB  . ALA F 1 8   ? -10.126 94.689  16.556  1.00 31.46  ? 8   ALA F CB  1 
ATOM   17775 N N   . GLU F 1 9   ? -9.737  97.924  15.920  1.00 40.30  ? 9   GLU F N   1 
ATOM   17776 C CA  . GLU F 1 9   ? -10.218 99.154  15.320  1.00 43.61  ? 9   GLU F CA  1 
ATOM   17777 C C   . GLU F 1 9   ? -9.081  99.904  14.654  1.00 42.03  ? 9   GLU F C   1 
ATOM   17778 O O   . GLU F 1 9   ? -9.289  100.496 13.606  1.00 48.22  ? 9   GLU F O   1 
ATOM   17779 C CB  . GLU F 1 9   ? -10.905 100.046 16.348  1.00 50.35  ? 9   GLU F CB  1 
ATOM   17780 C CG  . GLU F 1 9   ? -12.186 99.378  16.832  1.00 67.56  ? 9   GLU F CG  1 
ATOM   17781 C CD  . GLU F 1 9   ? -12.790 99.940  18.099  1.00 84.69  ? 9   GLU F CD  1 
ATOM   17782 O OE1 . GLU F 1 9   ? -12.009 100.408 18.964  1.00 87.92  ? 9   GLU F OE1 1 
ATOM   17783 O OE2 . GLU F 1 9   ? -14.037 99.859  18.232  1.00 95.79  ? 9   GLU F OE2 1 
ATOM   17784 N N   . LEU F 1 10  ? -7.907  99.937  15.286  1.00 39.21  ? 10  LEU F N   1 
ATOM   17785 C CA  . LEU F 1 10  ? -6.860  100.819 14.808  1.00 37.39  ? 10  LEU F CA  1 
ATOM   17786 C C   . LEU F 1 10  ? -6.208  100.238 13.551  1.00 36.48  ? 10  LEU F C   1 
ATOM   17787 O O   . LEU F 1 10  ? -5.913  100.956 12.605  1.00 35.90  ? 10  LEU F O   1 
ATOM   17788 C CB  . LEU F 1 10  ? -5.835  101.057 15.907  1.00 41.85  ? 10  LEU F CB  1 
ATOM   17789 C CG  . LEU F 1 10  ? -6.200  102.045 17.023  1.00 43.78  ? 10  LEU F CG  1 
ATOM   17790 C CD1 . LEU F 1 10  ? -5.133  102.011 18.133  1.00 41.95  ? 10  LEU F CD1 1 
ATOM   17791 C CD2 . LEU F 1 10  ? -6.340  103.477 16.527  1.00 44.67  ? 10  LEU F CD2 1 
ATOM   17792 N N   . ILE F 1 11  ? -5.978  98.931  13.506  1.00 32.47  ? 11  ILE F N   1 
ATOM   17793 C CA  . ILE F 1 11  ? -5.197  98.397  12.403  1.00 32.87  ? 11  ILE F CA  1 
ATOM   17794 C C   . ILE F 1 11  ? -5.912  98.621  11.073  1.00 32.51  ? 11  ILE F C   1 
ATOM   17795 O O   . ILE F 1 11  ? -5.263  99.009  10.110  1.00 34.00  ? 11  ILE F O   1 
ATOM   17796 C CB  . ILE F 1 11  ? -4.772  96.932  12.650  1.00 32.46  ? 11  ILE F CB  1 
ATOM   17797 C CG1 . ILE F 1 11  ? -3.542  96.885  13.565  1.00 34.65  ? 11  ILE F CG1 1 
ATOM   17798 C CG2 . ILE F 1 11  ? -4.506  96.187  11.347  1.00 32.72  ? 11  ILE F CG2 1 
ATOM   17799 C CD1 . ILE F 1 11  ? -3.215  95.513  14.139  1.00 37.37  ? 11  ILE F CD1 1 
ATOM   17800 N N   . PRO F 1 12  ? -7.225  98.333  10.908  1.00 35.82  ? 12  PRO F N   1 
ATOM   17801 C CA  . PRO F 1 12  ? -7.904  98.678  9.652   1.00 33.76  ? 12  PRO F CA  1 
ATOM   17802 C C   . PRO F 1 12  ? -7.761  100.144 9.240   1.00 32.77  ? 12  PRO F C   1 
ATOM   17803 O O   . PRO F 1 12  ? -7.597  100.435 8.063   1.00 36.94  ? 12  PRO F O   1 
ATOM   17804 C CB  . PRO F 1 12  ? -9.359  98.260  9.903   1.00 35.47  ? 12  PRO F CB  1 
ATOM   17805 C CG  . PRO F 1 12  ? -9.226  97.109  10.904  1.00 36.54  ? 12  PRO F CG  1 
ATOM   17806 C CD  . PRO F 1 12  ? -8.075  97.541  11.815  1.00 34.41  ? 12  PRO F CD  1 
ATOM   17807 N N   . GLN F 1 13  ? -7.757  101.074 10.196  1.00 34.32  ? 13  GLN F N   1 
ATOM   17808 C CA  . GLN F 1 13  ? -7.564  102.473 9.856   1.00 36.39  ? 13  GLN F CA  1 
ATOM   17809 C C   . GLN F 1 13  ? -6.174  102.661 9.290   1.00 34.94  ? 13  GLN F C   1 
ATOM   17810 O O   . GLN F 1 13  ? -5.991  103.320 8.275   1.00 37.79  ? 13  GLN F O   1 
ATOM   17811 C CB  . GLN F 1 13  ? -7.700  103.443 11.021  1.00 42.48  ? 13  GLN F CB  1 
ATOM   17812 C CG  . GLN F 1 13  ? -9.051  103.305 11.709  1.00 52.93  ? 13  GLN F CG  1 
ATOM   17813 C CD  . GLN F 1 13  ? -9.235  104.199 12.915  1.00 56.95  ? 13  GLN F CD  1 
ATOM   17814 O OE1 . GLN F 1 13  ? -8.493  105.168 13.143  1.00 56.60  ? 13  GLN F OE1 1 
ATOM   17815 N NE2 . GLN F 1 13  ? -10.278 103.877 13.665  1.00 54.40  ? 13  GLN F NE2 1 
ATOM   17816 N N   . TRP F 1 14  ? -5.193  102.092 9.974   1.00 35.38  ? 14  TRP F N   1 
ATOM   17817 C CA  . TRP F 1 14  ? -3.819  102.269 9.549   1.00 34.06  ? 14  TRP F CA  1 
ATOM   17818 C C   . TRP F 1 14  ? -3.614  101.609 8.193   1.00 30.06  ? 14  TRP F C   1 
ATOM   17819 O O   . TRP F 1 14  ? -3.007  102.194 7.319   1.00 29.32  ? 14  TRP F O   1 
ATOM   17820 C CB  . TRP F 1 14  ? -2.874  101.698 10.616  1.00 39.68  ? 14  TRP F CB  1 
ATOM   17821 C CG  . TRP F 1 14  ? -2.875  102.463 11.921  1.00 38.99  ? 14  TRP F CG  1 
ATOM   17822 C CD1 . TRP F 1 14  ? -3.124  103.792 12.095  1.00 36.33  ? 14  TRP F CD1 1 
ATOM   17823 C CD2 . TRP F 1 14  ? -2.581  101.933 13.235  1.00 37.94  ? 14  TRP F CD2 1 
ATOM   17824 N NE1 . TRP F 1 14  ? -3.002  104.127 13.413  1.00 38.60  ? 14  TRP F NE1 1 
ATOM   17825 C CE2 . TRP F 1 14  ? -2.673  103.014 14.141  1.00 41.05  ? 14  TRP F CE2 1 
ATOM   17826 C CE3 . TRP F 1 14  ? -2.240  100.665 13.736  1.00 35.33  ? 14  TRP F CE3 1 
ATOM   17827 C CZ2 . TRP F 1 14  ? -2.452  102.853 15.516  1.00 40.07  ? 14  TRP F CZ2 1 
ATOM   17828 C CZ3 . TRP F 1 14  ? -2.011  100.510 15.089  1.00 33.85  ? 14  TRP F CZ3 1 
ATOM   17829 C CH2 . TRP F 1 14  ? -2.112  101.593 15.967  1.00 35.57  ? 14  TRP F CH2 1 
ATOM   17830 N N   . ARG F 1 15  ? -4.138  100.389 8.011   1.00 32.79  ? 15  ARG F N   1 
ATOM   17831 C CA  . ARG F 1 15  ? -4.045  99.693  6.733   1.00 35.64  ? 15  ARG F CA  1 
ATOM   17832 C C   . ARG F 1 15  ? -4.455  100.637 5.591   1.00 38.78  ? 15  ARG F C   1 
ATOM   17833 O O   . ARG F 1 15  ? -3.694  100.810 4.641   1.00 36.96  ? 15  ARG F O   1 
ATOM   17834 C CB  . ARG F 1 15  ? -4.863  98.392  6.737   1.00 36.62  ? 15  ARG F CB  1 
ATOM   17835 C CG  . ARG F 1 15  ? -5.035  97.720  5.372   1.00 45.30  ? 15  ARG F CG  1 
ATOM   17836 C CD  . ARG F 1 15  ? -6.008  96.518  5.338   1.00 50.64  ? 15  ARG F CD  1 
ATOM   17837 N NE  . ARG F 1 15  ? -5.623  95.576  6.400   1.00 64.71  ? 15  ARG F NE  1 
ATOM   17838 C CZ  . ARG F 1 15  ? -6.309  95.110  7.466   1.00 67.12  ? 15  ARG F CZ  1 
ATOM   17839 N NH1 . ARG F 1 15  ? -7.544  95.535  7.729   1.00 63.52  ? 15  ARG F NH1 1 
ATOM   17840 N NH2 . ARG F 1 15  ? -5.724  94.213  8.266   1.00 59.00  ? 15  ARG F NH2 1 
ATOM   17841 N N   . ALA F 1 16  ? -5.652  101.245 5.707   1.00 36.60  ? 16  ALA F N   1 
ATOM   17842 C CA  . ALA F 1 16  ? -6.236  102.098 4.681   1.00 36.62  ? 16  ALA F CA  1 
ATOM   17843 C C   . ALA F 1 16  ? -5.402  103.362 4.467   1.00 36.12  ? 16  ALA F C   1 
ATOM   17844 O O   . ALA F 1 16  ? -5.154  103.762 3.328   1.00 35.05  ? 16  ALA F O   1 
ATOM   17845 C CB  . ALA F 1 16  ? -7.679  102.430 5.036   1.00 34.65  ? 16  ALA F CB  1 
ATOM   17846 N N   . GLU F 1 17  ? -4.961  103.986 5.558   1.00 38.20  ? 17  GLU F N   1 
ATOM   17847 C CA  . GLU F 1 17  ? -4.077  105.146 5.475   1.00 43.24  ? 17  GLU F CA  1 
ATOM   17848 C C   . GLU F 1 17  ? -2.820  104.813 4.665   1.00 42.57  ? 17  GLU F C   1 
ATOM   17849 O O   . GLU F 1 17  ? -2.349  105.642 3.880   1.00 44.11  ? 17  GLU F O   1 
ATOM   17850 C CB  . GLU F 1 17  ? -3.614  105.590 6.864   1.00 48.88  ? 17  GLU F CB  1 
ATOM   17851 C CG  . GLU F 1 17  ? -3.893  107.052 7.199   1.00 58.95  ? 17  GLU F CG  1 
ATOM   17852 C CD  . GLU F 1 17  ? -4.006  107.240 8.708   1.00 68.35  ? 17  GLU F CD  1 
ATOM   17853 O OE1 . GLU F 1 17  ? -5.139  107.210 9.272   1.00 62.43  ? 17  GLU F OE1 1 
ATOM   17854 O OE2 . GLU F 1 17  ? -2.920  107.403 9.313   1.00 73.26  ? 17  GLU F OE2 1 
ATOM   17855 N N   . VAL F 1 18  ? -2.262  103.611 4.886   1.00 34.92  ? 18  VAL F N   1 
ATOM   17856 C CA  . VAL F 1 18  ? -1.021  103.226 4.239   1.00 34.60  ? 18  VAL F CA  1 
ATOM   17857 C C   . VAL F 1 18  ? -1.295  103.095 2.746   1.00 35.19  ? 18  VAL F C   1 
ATOM   17858 O O   . VAL F 1 18  ? -0.561  103.661 1.932   1.00 35.28  ? 18  VAL F O   1 
ATOM   17859 C CB  . VAL F 1 18  ? -0.417  101.939 4.847   1.00 35.91  ? 18  VAL F CB  1 
ATOM   17860 C CG1 . VAL F 1 18  ? 0.655   101.302 3.974   1.00 36.16  ? 18  VAL F CG1 1 
ATOM   17861 C CG2 . VAL F 1 18  ? 0.179   102.197 6.219   1.00 36.18  ? 18  VAL F CG2 1 
ATOM   17862 N N   . ALA F 1 19  ? -2.371  102.367 2.412   1.00 33.18  ? 19  ALA F N   1 
ATOM   17863 C CA  . ALA F 1 19  ? -2.712  102.068 1.026   1.00 32.97  ? 19  ALA F CA  1 
ATOM   17864 C C   . ALA F 1 19  ? -2.827  103.369 0.247   1.00 32.75  ? 19  ALA F C   1 
ATOM   17865 O O   . ALA F 1 19  ? -2.241  103.483 -0.833  1.00 34.04  ? 19  ALA F O   1 
ATOM   17866 C CB  . ALA F 1 19  ? -3.986  101.252 0.944   1.00 32.66  ? 19  ALA F CB  1 
ATOM   17867 N N   . GLU F 1 20  ? -3.550  104.326 0.851   1.00 35.77  ? 20  GLU F N   1 
ATOM   17868 C CA  . GLU F 1 20  ? -3.732  105.672 0.322   1.00 38.18  ? 20  GLU F CA  1 
ATOM   17869 C C   . GLU F 1 20  ? -2.375  106.342 0.112   1.00 40.47  ? 20  GLU F C   1 
ATOM   17870 O O   . GLU F 1 20  ? -2.151  106.921 -0.949  1.00 44.59  ? 20  GLU F O   1 
ATOM   17871 C CB  . GLU F 1 20  ? -4.615  106.563 1.202   1.00 37.92  ? 20  GLU F CB  1 
ATOM   17872 C CG  . GLU F 1 20  ? -5.991  106.841 0.611   1.00 43.61  ? 20  GLU F CG  1 
ATOM   17873 C CD  . GLU F 1 20  ? -5.987  107.454 -0.789  1.00 48.93  ? 20  GLU F CD  1 
ATOM   17874 O OE1 . GLU F 1 20  ? -5.983  106.699 -1.771  1.00 51.93  ? 20  GLU F OE1 1 
ATOM   17875 O OE2 . GLU F 1 20  ? -5.941  108.693 -0.918  1.00 55.75  ? 20  GLU F OE2 1 
ATOM   17876 N N   . ILE F 1 21  ? -1.483  106.258 1.110   1.00 40.32  ? 21  ILE F N   1 
ATOM   17877 C CA  . ILE F 1 21  ? -0.193  106.925 1.040   1.00 41.55  ? 21  ILE F CA  1 
ATOM   17878 C C   . ILE F 1 21  ? 0.612   106.339 -0.117  1.00 40.00  ? 21  ILE F C   1 
ATOM   17879 O O   . ILE F 1 21  ? 1.192   107.104 -0.892  1.00 44.73  ? 21  ILE F O   1 
ATOM   17880 C CB  . ILE F 1 21  ? 0.567   106.874 2.386   1.00 43.77  ? 21  ILE F CB  1 
ATOM   17881 C CG1 . ILE F 1 21  ? -0.022  107.896 3.384   1.00 43.28  ? 21  ILE F CG1 1 
ATOM   17882 C CG2 . ILE F 1 21  ? 2.075   107.085 2.197   1.00 40.52  ? 21  ILE F CG2 1 
ATOM   17883 C CD1 . ILE F 1 21  ? 0.425   107.709 4.824   1.00 40.90  ? 21  ILE F CD1 1 
ATOM   17884 N N   . ARG F 1 22  ? 0.626   105.004 -0.239  1.00 38.02  ? 22  ARG F N   1 
ATOM   17885 C CA  . ARG F 1 22  ? 1.355   104.339 -1.315  1.00 41.12  ? 22  ARG F CA  1 
ATOM   17886 C C   . ARG F 1 22  ? 0.845   104.865 -2.661  1.00 47.38  ? 22  ARG F C   1 
ATOM   17887 O O   . ARG F 1 22  ? 1.641   105.213 -3.536  1.00 46.21  ? 22  ARG F O   1 
ATOM   17888 C CB  . ARG F 1 22  ? 1.262   102.807 -1.228  1.00 43.30  ? 22  ARG F CB  1 
ATOM   17889 C CG  . ARG F 1 22  ? 1.937   102.162 -0.011  1.00 48.79  ? 22  ARG F CG  1 
ATOM   17890 C CD  . ARG F 1 22  ? 1.912   100.614 0.033   1.00 49.29  ? 22  ARG F CD  1 
ATOM   17891 N NE  . ARG F 1 22  ? 2.782   99.965  -0.959  1.00 44.74  ? 22  ARG F NE  1 
ATOM   17892 C CZ  . ARG F 1 22  ? 2.772   98.700  -1.392  1.00 46.32  ? 22  ARG F CZ  1 
ATOM   17893 N NH1 . ARG F 1 22  ? 1.795   97.862  -1.090  1.00 48.03  ? 22  ARG F NH1 1 
ATOM   17894 N NH2 . ARG F 1 22  ? 3.742   98.283  -2.190  1.00 45.78  ? 22  ARG F NH2 1 
ATOM   17895 N N   . LYS F 1 23  ? -0.490  104.953 -2.778  1.00 47.93  ? 23  LYS F N   1 
ATOM   17896 C CA  . LYS F 1 23  ? -1.180  105.370 -3.989  1.00 49.95  ? 23  LYS F CA  1 
ATOM   17897 C C   . LYS F 1 23  ? -0.956  106.854 -4.253  1.00 45.63  ? 23  LYS F C   1 
ATOM   17898 O O   . LYS F 1 23  ? -0.675  107.232 -5.380  1.00 40.99  ? 23  LYS F O   1 
ATOM   17899 C CB  . LYS F 1 23  ? -2.686  105.078 -3.880  1.00 57.43  ? 23  LYS F CB  1 
ATOM   17900 C CG  . LYS F 1 23  ? -3.580  105.432 -5.074  1.00 58.80  ? 23  LYS F CG  1 
ATOM   17901 C CD  . LYS F 1 23  ? -5.048  105.060 -4.866  1.00 67.69  ? 23  LYS F CD  1 
ATOM   17902 C CE  . LYS F 1 23  ? -5.934  105.493 -6.006  1.00 77.78  ? 23  LYS F CE  1 
ATOM   17903 N NZ  . LYS F 1 23  ? -7.377  105.326 -5.783  1.00 81.84  ? 23  LYS F NZ  1 
ATOM   17904 N N   . LYS F 1 24  ? -1.090  107.692 -3.226  1.00 46.09  ? 24  LYS F N   1 
ATOM   17905 C CA  . LYS F 1 24  ? -1.086  109.132 -3.433  1.00 52.31  ? 24  LYS F CA  1 
ATOM   17906 C C   . LYS F 1 24  ? 0.335   109.708 -3.404  1.00 50.29  ? 24  LYS F C   1 
ATOM   17907 O O   . LYS F 1 24  ? 0.589   110.692 -4.088  1.00 49.20  ? 24  LYS F O   1 
ATOM   17908 C CB  . LYS F 1 24  ? -2.031  109.819 -2.438  1.00 59.64  ? 24  LYS F CB  1 
ATOM   17909 C CG  . LYS F 1 24  ? -2.107  111.342 -2.582  1.00 69.26  ? 24  LYS F CG  1 
ATOM   17910 C CD  . LYS F 1 24  ? -3.276  112.015 -1.863  1.00 80.37  ? 24  LYS F CD  1 
ATOM   17911 C CE  . LYS F 1 24  ? -4.586  111.847 -2.573  1.00 84.17  ? 24  LYS F CE  1 
ATOM   17912 N NZ  . LYS F 1 24  ? -5.691  112.239 -1.697  1.00 89.35  ? 24  LYS F NZ  1 
ATOM   17913 N N   . TYR F 1 25  ? 1.263   109.119 -2.631  1.00 45.93  ? 25  TYR F N   1 
ATOM   17914 C CA  . TYR F 1 25  ? 2.555   109.747 -2.398  1.00 44.65  ? 25  TYR F CA  1 
ATOM   17915 C C   . TYR F 1 25  ? 3.720   108.799 -2.700  1.00 43.43  ? 25  TYR F C   1 
ATOM   17916 O O   . TYR F 1 25  ? 4.860   109.074 -2.287  1.00 42.51  ? 25  TYR F O   1 
ATOM   17917 C CB  . TYR F 1 25  ? 2.534   110.229 -0.944  1.00 50.41  ? 25  TYR F CB  1 
ATOM   17918 C CG  . TYR F 1 25  ? 1.535   111.339 -0.662  1.00 55.19  ? 25  TYR F CG  1 
ATOM   17919 C CD1 . TYR F 1 25  ? 1.495   112.484 -1.448  1.00 61.76  ? 25  TYR F CD1 1 
ATOM   17920 C CD2 . TYR F 1 25  ? 0.629   111.239 0.385   1.00 58.34  ? 25  TYR F CD2 1 
ATOM   17921 C CE1 . TYR F 1 25  ? 0.592   113.505 -1.193  1.00 63.42  ? 25  TYR F CE1 1 
ATOM   17922 C CE2 . TYR F 1 25  ? -0.277  112.253 0.654   1.00 58.28  ? 25  TYR F CE2 1 
ATOM   17923 C CZ  . TYR F 1 25  ? -0.300  113.386 -0.140  1.00 61.16  ? 25  TYR F CZ  1 
ATOM   17924 O OH  . TYR F 1 25  ? -1.192  114.391 0.101   1.00 52.98  ? 25  TYR F OH  1 
ATOM   17925 N N   . GLY F 1 26  ? 3.445   107.708 -3.443  1.00 36.76  ? 26  GLY F N   1 
ATOM   17926 C CA  . GLY F 1 26  ? 4.472   106.788 -3.921  1.00 34.14  ? 26  GLY F CA  1 
ATOM   17927 C C   . GLY F 1 26  ? 5.685   107.471 -4.569  1.00 36.66  ? 26  GLY F C   1 
ATOM   17928 O O   . GLY F 1 26  ? 6.812   107.129 -4.246  1.00 34.96  ? 26  GLY F O   1 
ATOM   17929 N N   . ASN F 1 27  ? 5.455   108.418 -5.497  1.00 44.48  ? 27  ASN F N   1 
ATOM   17930 C CA  . ASN F 1 27  ? 6.520   109.084 -6.238  1.00 47.34  ? 27  ASN F CA  1 
ATOM   17931 C C   . ASN F 1 27  ? 7.027   110.338 -5.521  1.00 44.06  ? 27  ASN F C   1 
ATOM   17932 O O   . ASN F 1 27  ? 7.750   111.124 -6.117  1.00 44.86  ? 27  ASN F O   1 
ATOM   17933 C CB  . ASN F 1 27  ? 6.163   109.434 -7.693  1.00 57.89  ? 27  ASN F CB  1 
ATOM   17934 C CG  . ASN F 1 27  ? 4.723   109.828 -7.983  1.00 62.26  ? 27  ASN F CG  1 
ATOM   17935 O OD1 . ASN F 1 27  ? 4.232   110.872 -7.534  1.00 58.77  ? 27  ASN F OD1 1 
ATOM   17936 N ND2 . ASN F 1 27  ? 4.044   109.046 -8.815  1.00 77.17  ? 27  ASN F ND2 1 
ATOM   17937 N N   . ARG F 1 28  ? 6.703   110.531 -4.242  1.00 42.71  ? 28  ARG F N   1 
ATOM   17938 C CA  . ARG F 1 28  ? 7.341   111.608 -3.501  1.00 44.61  ? 28  ARG F CA  1 
ATOM   17939 C C   . ARG F 1 28  ? 8.791   111.226 -3.198  1.00 44.46  ? 28  ARG F C   1 
ATOM   17940 O O   . ARG F 1 28  ? 9.047   110.140 -2.691  1.00 47.96  ? 28  ARG F O   1 
ATOM   17941 C CB  . ARG F 1 28  ? 6.522   111.982 -2.258  1.00 46.42  ? 28  ARG F CB  1 
ATOM   17942 C CG  . ARG F 1 28  ? 5.230   112.749 -2.555  1.00 49.30  ? 28  ARG F CG  1 
ATOM   17943 C CD  . ARG F 1 28  ? 5.504   113.943 -3.498  1.00 51.00  ? 28  ARG F CD  1 
ATOM   17944 N NE  . ARG F 1 28  ? 4.578   115.081 -3.469  1.00 51.92  ? 28  ARG F NE  1 
ATOM   17945 C CZ  . ARG F 1 28  ? 3.354   115.075 -3.947  1.00 51.58  ? 28  ARG F CZ  1 
ATOM   17946 N NH1 . ARG F 1 28  ? 2.818   113.980 -4.467  1.00 57.48  ? 28  ARG F NH1 1 
ATOM   17947 N NH2 . ARG F 1 28  ? 2.660   116.183 -3.886  1.00 54.37  ? 28  ARG F NH2 1 
ATOM   17948 N N   . LYS F 1 29  ? 9.733   112.128 -3.520  1.00 44.04  ? 29  LYS F N   1 
ATOM   17949 C CA  . LYS F 1 29  ? 11.154  111.914 -3.264  1.00 44.81  ? 29  LYS F CA  1 
ATOM   17950 C C   . LYS F 1 29  ? 11.510  112.345 -1.839  1.00 43.57  ? 29  LYS F C   1 
ATOM   17951 O O   . LYS F 1 29  ? 11.063  113.392 -1.392  1.00 48.21  ? 29  LYS F O   1 
ATOM   17952 C CB  . LYS F 1 29  ? 11.996  112.656 -4.309  1.00 44.79  ? 29  LYS F CB  1 
ATOM   17953 C CG  . LYS F 1 29  ? 13.382  113.036 -3.848  1.00 45.58  ? 29  LYS F CG  1 
ATOM   17954 C CD  . LYS F 1 29  ? 14.399  113.305 -4.940  1.00 46.83  ? 29  LYS F CD  1 
ATOM   17955 C CE  . LYS F 1 29  ? 15.510  114.138 -4.383  1.00 47.83  ? 29  LYS F CE  1 
ATOM   17956 N NZ  . LYS F 1 29  ? 16.620  114.277 -5.321  1.00 48.08  ? 29  LYS F NZ  1 
ATOM   17957 N N   . THR F 1 30  ? 12.331  111.543 -1.136  1.00 42.08  ? 30  THR F N   1 
ATOM   17958 C CA  . THR F 1 30  ? 12.784  111.876 0.215   1.00 39.21  ? 30  THR F CA  1 
ATOM   17959 C C   . THR F 1 30  ? 14.254  112.278 0.186   1.00 38.20  ? 30  THR F C   1 
ATOM   17960 O O   . THR F 1 30  ? 14.701  112.968 1.079   1.00 40.65  ? 30  THR F O   1 
ATOM   17961 C CB  . THR F 1 30  ? 12.571  110.717 1.195   1.00 34.88  ? 30  THR F CB  1 
ATOM   17962 O OG1 . THR F 1 30  ? 13.286  109.573 0.736   1.00 35.74  ? 30  THR F OG1 1 
ATOM   17963 C CG2 . THR F 1 30  ? 11.113  110.300 1.311   1.00 38.08  ? 30  THR F CG2 1 
ATOM   17964 N N   . MET F 1 31  ? 15.014  111.790 -0.792  1.00 38.69  ? 31  MET F N   1 
ATOM   17965 C CA  . MET F 1 31  ? 16.450  112.005 -0.832  1.00 40.54  ? 31  MET F CA  1 
ATOM   17966 C C   . MET F 1 31  ? 17.028  111.302 -2.057  1.00 42.19  ? 31  MET F C   1 
ATOM   17967 O O   . MET F 1 31  ? 16.320  110.539 -2.716  1.00 38.46  ? 31  MET F O   1 
ATOM   17968 C CB  . MET F 1 31  ? 17.157  111.451 0.406   1.00 40.54  ? 31  MET F CB  1 
ATOM   17969 C CG  . MET F 1 31  ? 16.831  110.001 0.698   1.00 47.26  ? 31  MET F CG  1 
ATOM   17970 S SD  . MET F 1 31  ? 17.537  109.411 2.254   1.00 46.72  ? 31  MET F SD  1 
ATOM   17971 C CE  . MET F 1 31  ? 19.300  109.378 1.903   1.00 41.30  ? 31  MET F CE  1 
ATOM   17972 N N   . ASP F 1 32  ? 18.308  111.599 -2.334  1.00 42.58  ? 32  ASP F N   1 
ATOM   17973 C CA  . ASP F 1 32  ? 19.090  110.967 -3.383  1.00 41.61  ? 32  ASP F CA  1 
ATOM   17974 C C   . ASP F 1 32  ? 19.612  109.636 -2.844  1.00 39.08  ? 32  ASP F C   1 
ATOM   17975 O O   . ASP F 1 32  ? 19.983  109.581 -1.675  1.00 41.56  ? 32  ASP F O   1 
ATOM   17976 C CB  . ASP F 1 32  ? 20.225  111.888 -3.823  1.00 46.81  ? 32  ASP F CB  1 
ATOM   17977 C CG  . ASP F 1 32  ? 19.833  113.112 -4.653  1.00 50.82  ? 32  ASP F CG  1 
ATOM   17978 O OD1 . ASP F 1 32  ? 18.742  113.068 -5.263  1.00 45.94  ? 32  ASP F OD1 1 
ATOM   17979 O OD2 . ASP F 1 32  ? 20.625  114.103 -4.699  1.00 49.43  ? 32  ASP F OD2 1 
ATOM   17980 N N   . CYS F 1 33  ? 19.574  108.577 -3.674  1.00 35.39  ? 33  CYS F N   1 
ATOM   17981 C CA  . CYS F 1 33  ? 20.287  107.323 -3.438  1.00 34.19  ? 33  CYS F CA  1 
ATOM   17982 C C   . CYS F 1 33  ? 21.619  107.343 -4.197  1.00 36.11  ? 33  CYS F C   1 
ATOM   17983 O O   . CYS F 1 33  ? 21.665  107.690 -5.380  1.00 30.72  ? 33  CYS F O   1 
ATOM   17984 C CB  . CYS F 1 33  ? 19.407  106.138 -3.831  1.00 34.31  ? 33  CYS F CB  1 
ATOM   17985 S SG  . CYS F 1 33  ? 20.140  104.509 -3.523  1.00 36.87  ? 33  CYS F SG  1 
ATOM   17986 N N   . THR F 1 34  ? 22.708  106.979 -3.497  1.00 37.51  ? 34  THR F N   1 
ATOM   17987 C CA  . THR F 1 34  ? 24.071  107.196 -3.963  1.00 35.66  ? 34  THR F CA  1 
ATOM   17988 C C   . THR F 1 34  ? 24.829  105.873 -3.966  1.00 37.93  ? 34  THR F C   1 
ATOM   17989 O O   . THR F 1 34  ? 24.443  104.903 -3.322  1.00 37.43  ? 34  THR F O   1 
ATOM   17990 C CB  . THR F 1 34  ? 24.830  108.198 -3.081  1.00 42.07  ? 34  THR F CB  1 
ATOM   17991 O OG1 . THR F 1 34  ? 25.161  107.643 -1.805  1.00 41.62  ? 34  THR F OG1 1 
ATOM   17992 C CG2 . THR F 1 34  ? 24.087  109.505 -2.880  1.00 39.80  ? 34  THR F CG2 1 
ATOM   17993 N N   . ILE F 1 35  ? 25.937  105.871 -4.708  1.00 43.13  ? 35  ILE F N   1 
ATOM   17994 C CA  . ILE F 1 35  ? 26.920  104.798 -4.707  1.00 40.51  ? 35  ILE F CA  1 
ATOM   17995 C C   . ILE F 1 35  ? 27.363  104.545 -3.263  1.00 36.93  ? 35  ILE F C   1 
ATOM   17996 O O   . ILE F 1 35  ? 27.496  103.396 -2.848  1.00 37.01  ? 35  ILE F O   1 
ATOM   17997 C CB  . ILE F 1 35  ? 28.094  105.189 -5.632  1.00 38.62  ? 35  ILE F CB  1 
ATOM   17998 C CG1 . ILE F 1 35  ? 27.633  105.458 -7.071  1.00 39.29  ? 35  ILE F CG1 1 
ATOM   17999 C CG2 . ILE F 1 35  ? 29.218  104.156 -5.599  1.00 39.46  ? 35  ILE F CG2 1 
ATOM   18000 C CD1 . ILE F 1 35  ? 26.910  104.295 -7.722  1.00 39.56  ? 35  ILE F CD1 1 
ATOM   18001 N N   . GLY F 1 36  ? 27.574  105.646 -2.530  1.00 33.75  ? 36  GLY F N   1 
ATOM   18002 C CA  . GLY F 1 36  ? 27.864  105.661 -1.107  1.00 33.83  ? 36  GLY F CA  1 
ATOM   18003 C C   . GLY F 1 36  ? 26.900  104.794 -0.302  1.00 35.40  ? 36  GLY F C   1 
ATOM   18004 O O   . GLY F 1 36  ? 27.356  103.993 0.517   1.00 34.42  ? 36  GLY F O   1 
ATOM   18005 N N   . HIS F 1 37  ? 25.587  104.933 -0.556  1.00 34.05  ? 37  HIS F N   1 
ATOM   18006 C CA  . HIS F 1 37  ? 24.578  104.095 0.089   1.00 35.12  ? 37  HIS F CA  1 
ATOM   18007 C C   . HIS F 1 37  ? 24.804  102.601 -0.163  1.00 37.30  ? 37  HIS F C   1 
ATOM   18008 O O   . HIS F 1 37  ? 24.679  101.788 0.759   1.00 38.85  ? 37  HIS F O   1 
ATOM   18009 C CB  . HIS F 1 37  ? 23.151  104.504 -0.300  1.00 31.39  ? 37  HIS F CB  1 
ATOM   18010 C CG  . HIS F 1 37  ? 22.800  105.815 0.267   1.00 31.48  ? 37  HIS F CG  1 
ATOM   18011 N ND1 . HIS F 1 37  ? 22.389  106.884 -0.489  1.00 32.26  ? 37  HIS F ND1 1 
ATOM   18012 C CD2 . HIS F 1 37  ? 22.899  106.263 1.532   1.00 36.23  ? 37  HIS F CD2 1 
ATOM   18013 C CE1 . HIS F 1 37  ? 22.230  107.939 0.304   1.00 36.92  ? 37  HIS F CE1 1 
ATOM   18014 N NE2 . HIS F 1 37  ? 22.516  107.584 1.544   1.00 35.27  ? 37  HIS F NE2 1 
ATOM   18015 N N   . ALA F 1 38  ? 25.119  102.226 -1.407  1.00 36.62  ? 38  ALA F N   1 
ATOM   18016 C CA  . ALA F 1 38  ? 25.226  100.814 -1.732  1.00 34.00  ? 38  ALA F CA  1 
ATOM   18017 C C   . ALA F 1 38  ? 26.462  100.203 -1.079  1.00 31.11  ? 38  ALA F C   1 
ATOM   18018 O O   . ALA F 1 38  ? 26.413  99.045  -0.665  1.00 30.96  ? 38  ALA F O   1 
ATOM   18019 C CB  . ALA F 1 38  ? 25.238  100.619 -3.223  1.00 34.55  ? 38  ALA F CB  1 
ATOM   18020 N N   . TYR F 1 39  ? 27.558  100.979 -1.030  1.00 29.28  ? 39  TYR F N   1 
ATOM   18021 C CA  . TYR F 1 39  ? 28.832  100.502 -0.513  1.00 31.63  ? 39  TYR F CA  1 
ATOM   18022 C C   . TYR F 1 39  ? 29.003  100.822 0.981   1.00 32.70  ? 39  TYR F C   1 
ATOM   18023 O O   . TYR F 1 39  ? 29.986  100.339 1.552   1.00 30.02  ? 39  TYR F O   1 
ATOM   18024 C CB  . TYR F 1 39  ? 30.017  101.054 -1.315  1.00 30.66  ? 39  TYR F CB  1 
ATOM   18025 C CG  . TYR F 1 39  ? 30.183  100.358 -2.658  1.00 31.89  ? 39  TYR F CG  1 
ATOM   18026 C CD1 . TYR F 1 39  ? 29.541  100.826 -3.808  1.00 34.21  ? 39  TYR F CD1 1 
ATOM   18027 C CD2 . TYR F 1 39  ? 30.982  99.229  -2.777  1.00 32.77  ? 39  TYR F CD2 1 
ATOM   18028 C CE1 . TYR F 1 39  ? 29.687  100.188 -5.036  1.00 35.45  ? 39  TYR F CE1 1 
ATOM   18029 C CE2 . TYR F 1 39  ? 31.117  98.563  -3.989  1.00 34.07  ? 39  TYR F CE2 1 
ATOM   18030 C CZ  . TYR F 1 39  ? 30.456  99.034  -5.118  1.00 35.72  ? 39  TYR F CZ  1 
ATOM   18031 O OH  . TYR F 1 39  ? 30.595  98.356  -6.289  1.00 28.57  ? 39  TYR F OH  1 
ATOM   18032 N N   . GLY F 1 40  ? 28.049  101.568 1.596   1.00 28.08  ? 40  GLY F N   1 
ATOM   18033 C CA  . GLY F 1 40  ? 28.178  102.123 2.941   1.00 26.71  ? 40  GLY F CA  1 
ATOM   18034 C C   . GLY F 1 40  ? 27.063  101.673 3.899   1.00 28.91  ? 40  GLY F C   1 
ATOM   18035 O O   . GLY F 1 40  ? 26.857  102.273 4.950   1.00 29.52  ? 40  GLY F O   1 
ATOM   18036 N N   . GLY F 1 41  ? 26.352  100.592 3.549   1.00 27.89  ? 41  GLY F N   1 
ATOM   18037 C CA  . GLY F 1 41  ? 25.454  99.925  4.465   1.00 25.04  ? 41  GLY F CA  1 
ATOM   18038 C C   . GLY F 1 41  ? 24.145  100.690 4.552   1.00 27.42  ? 41  GLY F C   1 
ATOM   18039 O O   . GLY F 1 41  ? 23.425  100.608 5.553   1.00 22.35  ? 41  GLY F O   1 
ATOM   18040 N N   . MET F 1 42  ? 23.858  101.426 3.472   1.00 29.90  ? 42  MET F N   1 
ATOM   18041 C CA  . MET F 1 42  ? 22.615  102.162 3.349   1.00 30.23  ? 42  MET F CA  1 
ATOM   18042 C C   . MET F 1 42  ? 22.573  103.317 4.354   1.00 29.13  ? 42  MET F C   1 
ATOM   18043 O O   . MET F 1 42  ? 21.509  103.820 4.681   1.00 32.78  ? 42  MET F O   1 
ATOM   18044 C CB  . MET F 1 42  ? 21.415  101.236 3.587   1.00 29.66  ? 42  MET F CB  1 
ATOM   18045 C CG  . MET F 1 42  ? 21.357  99.985  2.744   1.00 27.76  ? 42  MET F CG  1 
ATOM   18046 S SD  . MET F 1 42  ? 19.649  99.380  2.742   1.00 33.06  ? 42  MET F SD  1 
ATOM   18047 C CE  . MET F 1 42  ? 19.833  97.717  2.084   1.00 32.41  ? 42  MET F CE  1 
ATOM   18048 N N   . ARG F 1 43  ? 23.717  103.781 4.844   1.00 30.64  ? 43  ARG F N   1 
ATOM   18049 C CA  . ARG F 1 43  ? 23.692  104.715 5.958   1.00 32.61  ? 43  ARG F CA  1 
ATOM   18050 C C   . ARG F 1 43  ? 22.955  105.991 5.547   1.00 29.33  ? 43  ARG F C   1 
ATOM   18051 O O   . ARG F 1 43  ? 23.359  106.660 4.613   1.00 30.63  ? 43  ARG F O   1 
ATOM   18052 C CB  . ARG F 1 43  ? 25.107  105.051 6.442   1.00 33.45  ? 43  ARG F CB  1 
ATOM   18053 C CG  . ARG F 1 43  ? 25.121  105.676 7.833   1.00 31.94  ? 43  ARG F CG  1 
ATOM   18054 C CD  . ARG F 1 43  ? 24.785  104.664 8.932   1.00 30.57  ? 43  ARG F CD  1 
ATOM   18055 N NE  . ARG F 1 43  ? 25.895  103.715 9.055   1.00 31.53  ? 43  ARG F NE  1 
ATOM   18056 C CZ  . ARG F 1 43  ? 25.907  102.494 8.547   1.00 33.05  ? 43  ARG F CZ  1 
ATOM   18057 N NH1 . ARG F 1 43  ? 24.844  102.010 7.949   1.00 35.11  ? 43  ARG F NH1 1 
ATOM   18058 N NH2 . ARG F 1 43  ? 26.985  101.750 8.623   1.00 33.78  ? 43  ARG F NH2 1 
ATOM   18059 N N   . GLY F 1 44  ? 21.883  106.325 6.271   1.00 30.76  ? 44  GLY F N   1 
ATOM   18060 C CA  . GLY F 1 44  ? 21.116  107.549 6.050   1.00 30.67  ? 44  GLY F CA  1 
ATOM   18061 C C   . GLY F 1 44  ? 19.950  107.367 5.072   1.00 30.22  ? 44  GLY F C   1 
ATOM   18062 O O   . GLY F 1 44  ? 19.074  108.219 4.993   1.00 31.75  ? 44  GLY F O   1 
ATOM   18063 N N   . LEU F 1 45  ? 19.908  106.237 4.362   1.00 28.71  ? 45  LEU F N   1 
ATOM   18064 C CA  . LEU F 1 45  ? 18.939  106.019 3.311   1.00 31.19  ? 45  LEU F CA  1 
ATOM   18065 C C   . LEU F 1 45  ? 17.595  105.646 3.936   1.00 34.10  ? 45  LEU F C   1 
ATOM   18066 O O   . LEU F 1 45  ? 17.517  104.676 4.683   1.00 36.91  ? 45  LEU F O   1 
ATOM   18067 C CB  . LEU F 1 45  ? 19.489  104.909 2.417   1.00 32.28  ? 45  LEU F CB  1 
ATOM   18068 C CG  . LEU F 1 45  ? 18.688  104.606 1.150   1.00 35.11  ? 45  LEU F CG  1 
ATOM   18069 C CD1 . LEU F 1 45  ? 18.711  105.754 0.171   1.00 37.03  ? 45  LEU F CD1 1 
ATOM   18070 C CD2 . LEU F 1 45  ? 19.219  103.350 0.501   1.00 36.44  ? 45  LEU F CD2 1 
ATOM   18071 N N   . LYS F 1 46  ? 16.536  106.385 3.581   1.00 33.08  ? 46  LYS F N   1 
ATOM   18072 C CA  . LYS F 1 46  ? 15.224  106.209 4.181   1.00 35.62  ? 46  LYS F CA  1 
ATOM   18073 C C   . LYS F 1 46  ? 14.477  105.077 3.480   1.00 36.03  ? 46  LYS F C   1 
ATOM   18074 O O   . LYS F 1 46  ? 13.562  105.318 2.689   1.00 35.80  ? 46  LYS F O   1 
ATOM   18075 C CB  . LYS F 1 46  ? 14.463  107.540 4.124   1.00 41.18  ? 46  LYS F CB  1 
ATOM   18076 C CG  . LYS F 1 46  ? 15.191  108.663 4.849   1.00 41.37  ? 46  LYS F CG  1 
ATOM   18077 C CD  . LYS F 1 46  ? 14.408  109.930 5.142   1.00 41.44  ? 46  LYS F CD  1 
ATOM   18078 C CE  . LYS F 1 46  ? 15.344  110.986 5.636   1.00 41.50  ? 46  LYS F CE  1 
ATOM   18079 N NZ  . LYS F 1 46  ? 14.564  112.119 6.108   1.00 43.85  ? 46  LYS F NZ  1 
ATOM   18080 N N   . ALA F 1 47  ? 14.856  103.841 3.825   1.00 33.31  ? 47  ALA F N   1 
ATOM   18081 C CA  . ALA F 1 47  ? 14.492  102.664 3.058   1.00 33.82  ? 47  ALA F CA  1 
ATOM   18082 C C   . ALA F 1 47  ? 13.465  101.778 3.772   1.00 32.16  ? 47  ALA F C   1 
ATOM   18083 O O   . ALA F 1 47  ? 13.056  100.737 3.258   1.00 31.78  ? 47  ALA F O   1 
ATOM   18084 C CB  . ALA F 1 47  ? 15.772  101.916 2.752   1.00 34.39  ? 47  ALA F CB  1 
ATOM   18085 N N   . LEU F 1 48  ? 13.068  102.172 4.981   1.00 36.74  ? 48  LEU F N   1 
ATOM   18086 C CA  . LEU F 1 48  ? 12.219  101.351 5.839   1.00 36.79  ? 48  LEU F CA  1 
ATOM   18087 C C   . LEU F 1 48  ? 11.196  102.242 6.529   1.00 32.55  ? 48  LEU F C   1 
ATOM   18088 O O   . LEU F 1 48  ? 11.502  103.408 6.796   1.00 29.30  ? 48  LEU F O   1 
ATOM   18089 C CB  . LEU F 1 48  ? 13.033  100.645 6.915   1.00 36.11  ? 48  LEU F CB  1 
ATOM   18090 C CG  . LEU F 1 48  ? 13.925  99.495  6.465   1.00 37.19  ? 48  LEU F CG  1 
ATOM   18091 C CD1 . LEU F 1 48  ? 14.716  99.115  7.701   1.00 37.08  ? 48  LEU F CD1 1 
ATOM   18092 C CD2 . LEU F 1 48  ? 13.152  98.296  5.920   1.00 39.43  ? 48  LEU F CD2 1 
ATOM   18093 N N   . VAL F 1 49  ? 10.051  101.632 6.867   1.00 30.52  ? 49  VAL F N   1 
ATOM   18094 C CA  . VAL F 1 49  ? 9.014   102.246 7.674   1.00 30.66  ? 49  VAL F CA  1 
ATOM   18095 C C   . VAL F 1 49  ? 9.002   101.610 9.062   1.00 29.09  ? 49  VAL F C   1 
ATOM   18096 O O   . VAL F 1 49  ? 8.939   100.387 9.194   1.00 25.97  ? 49  VAL F O   1 
ATOM   18097 C CB  . VAL F 1 49  ? 7.649   102.031 6.995   1.00 33.69  ? 49  VAL F CB  1 
ATOM   18098 C CG1 . VAL F 1 49  ? 6.505   102.264 7.971   1.00 38.36  ? 49  VAL F CG1 1 
ATOM   18099 C CG2 . VAL F 1 49  ? 7.472   102.923 5.783   1.00 36.82  ? 49  VAL F CG2 1 
ATOM   18100 N N   . CYS F 1 50  ? 8.972   102.450 10.093  1.00 27.45  ? 50  CYS F N   1 
ATOM   18101 C CA  . CYS F 1 50  ? 8.714   101.978 11.442  1.00 28.79  ? 50  CYS F CA  1 
ATOM   18102 C C   . CYS F 1 50  ? 7.850   102.980 12.202  1.00 28.70  ? 50  CYS F C   1 
ATOM   18103 O O   . CYS F 1 50  ? 8.148   104.168 12.187  1.00 29.06  ? 50  CYS F O   1 
ATOM   18104 C CB  . CYS F 1 50  ? 10.020  101.752 12.191  1.00 31.86  ? 50  CYS F CB  1 
ATOM   18105 S SG  . CYS F 1 50  ? 9.785   101.302 13.930  1.00 32.24  ? 50  CYS F SG  1 
ATOM   18106 N N   . ASP F 1 51  ? 6.790   102.500 12.877  1.00 30.61  ? 51  ASP F N   1 
ATOM   18107 C CA  . ASP F 1 51  ? 5.866   103.377 13.590  1.00 30.89  ? 51  ASP F CA  1 
ATOM   18108 C C   . ASP F 1 51  ? 5.937   103.189 15.110  1.00 29.88  ? 51  ASP F C   1 
ATOM   18109 O O   . ASP F 1 51  ? 5.353   103.973 15.875  1.00 29.29  ? 51  ASP F O   1 
ATOM   18110 C CB  . ASP F 1 51  ? 4.447   103.191 13.063  1.00 32.47  ? 51  ASP F CB  1 
ATOM   18111 C CG  . ASP F 1 51  ? 4.177   103.806 11.701  1.00 31.77  ? 51  ASP F CG  1 
ATOM   18112 O OD1 . ASP F 1 51  ? 4.724   104.892 11.441  1.00 31.55  ? 51  ASP F OD1 1 
ATOM   18113 O OD2 . ASP F 1 51  ? 3.380   103.223 10.941  1.00 33.03  ? 51  ASP F OD2 1 
ATOM   18114 N N   . THR F 1 52  ? 6.634   102.142 15.570  1.00 28.61  ? 52  THR F N   1 
ATOM   18115 C CA  . THR F 1 52  ? 6.800   101.945 17.003  1.00 27.29  ? 52  THR F CA  1 
ATOM   18116 C C   . THR F 1 52  ? 7.721   103.016 17.593  1.00 28.29  ? 52  THR F C   1 
ATOM   18117 O O   . THR F 1 52  ? 7.438   103.600 18.650  1.00 31.07  ? 52  THR F O   1 
ATOM   18118 C CB  . THR F 1 52  ? 7.306   100.538 17.257  1.00 25.70  ? 52  THR F CB  1 
ATOM   18119 O OG1 . THR F 1 52  ? 8.535   100.369 16.562  1.00 25.57  ? 52  THR F OG1 1 
ATOM   18120 C CG2 . THR F 1 52  ? 6.284   99.518  16.792  1.00 28.75  ? 52  THR F CG2 1 
ATOM   18121 N N   . SER F 1 53  ? 8.815   103.290 16.886  1.00 27.04  ? 53  SER F N   1 
ATOM   18122 C CA  . SER F 1 53  ? 9.816   104.203 17.407  1.00 28.77  ? 53  SER F CA  1 
ATOM   18123 C C   . SER F 1 53  ? 10.620  104.847 16.272  1.00 30.24  ? 53  SER F C   1 
ATOM   18124 O O   . SER F 1 53  ? 10.565  104.418 15.114  1.00 26.38  ? 53  SER F O   1 
ATOM   18125 C CB  . SER F 1 53  ? 10.697  103.497 18.381  1.00 25.33  ? 53  SER F CB  1 
ATOM   18126 O OG  . SER F 1 53  ? 11.458  102.520 17.693  1.00 25.51  ? 53  SER F OG  1 
ATOM   18127 N N   . GLU F 1 54  ? 11.341  105.910 16.647  1.00 29.70  ? 54  GLU F N   1 
ATOM   18128 C CA  . GLU F 1 54  ? 12.052  106.771 15.724  1.00 29.31  ? 54  GLU F CA  1 
ATOM   18129 C C   . GLU F 1 54  ? 13.283  107.277 16.458  1.00 30.53  ? 54  GLU F C   1 
ATOM   18130 O O   . GLU F 1 54  ? 13.167  107.817 17.557  1.00 29.04  ? 54  GLU F O   1 
ATOM   18131 C CB  . GLU F 1 54  ? 11.132  107.929 15.333  1.00 33.02  ? 54  GLU F CB  1 
ATOM   18132 C CG  . GLU F 1 54  ? 11.602  108.723 14.119  1.00 34.70  ? 54  GLU F CG  1 
ATOM   18133 C CD  . GLU F 1 54  ? 10.781  109.957 13.749  1.00 38.93  ? 54  GLU F CD  1 
ATOM   18134 O OE1 . GLU F 1 54  ? 11.296  110.656 12.832  1.00 34.89  ? 54  GLU F OE1 1 
ATOM   18135 O OE2 . GLU F 1 54  ? 9.693   110.230 14.353  1.00 34.74  ? 54  GLU F OE2 1 
ATOM   18136 N N   . VAL F 1 55  ? 14.456  107.116 15.844  1.00 30.29  ? 55  VAL F N   1 
ATOM   18137 C CA  . VAL F 1 55  ? 15.692  107.541 16.475  1.00 30.84  ? 55  VAL F CA  1 
ATOM   18138 C C   . VAL F 1 55  ? 16.132  108.844 15.822  1.00 35.25  ? 55  VAL F C   1 
ATOM   18139 O O   . VAL F 1 55  ? 16.384  108.886 14.611  1.00 34.56  ? 55  VAL F O   1 
ATOM   18140 C CB  . VAL F 1 55  ? 16.799  106.480 16.392  1.00 28.21  ? 55  VAL F CB  1 
ATOM   18141 C CG1 . VAL F 1 55  ? 18.110  107.004 16.951  1.00 27.16  ? 55  VAL F CG1 1 
ATOM   18142 C CG2 . VAL F 1 55  ? 16.409  105.189 17.102  1.00 28.18  ? 55  VAL F CG2 1 
ATOM   18143 N N   . PHE F 1 56  ? 16.231  109.892 16.650  1.00 34.75  ? 56  PHE F N   1 
ATOM   18144 C CA  . PHE F 1 56  ? 16.671  111.196 16.188  1.00 34.65  ? 56  PHE F CA  1 
ATOM   18145 C C   . PHE F 1 56  ? 18.179  111.280 16.378  1.00 37.92  ? 56  PHE F C   1 
ATOM   18146 O O   . PHE F 1 56  ? 18.706  110.979 17.454  1.00 32.53  ? 56  PHE F O   1 
ATOM   18147 C CB  . PHE F 1 56  ? 15.920  112.310 16.915  1.00 33.85  ? 56  PHE F CB  1 
ATOM   18148 C CG  . PHE F 1 56  ? 14.435  112.327 16.604  1.00 33.70  ? 56  PHE F CG  1 
ATOM   18149 C CD1 . PHE F 1 56  ? 13.598  111.307 17.053  1.00 34.53  ? 56  PHE F CD1 1 
ATOM   18150 C CD2 . PHE F 1 56  ? 13.881  113.335 15.824  1.00 37.20  ? 56  PHE F CD2 1 
ATOM   18151 C CE1 . PHE F 1 56  ? 12.237  111.322 16.763  1.00 35.95  ? 56  PHE F CE1 1 
ATOM   18152 C CE2 . PHE F 1 56  ? 12.514  113.344 15.537  1.00 37.58  ? 56  PHE F CE2 1 
ATOM   18153 C CZ  . PHE F 1 56  ? 11.696  112.347 16.016  1.00 35.80  ? 56  PHE F CZ  1 
ATOM   18154 N N   . PRO F 1 57  ? 18.934  111.668 15.327  1.00 38.83  ? 57  PRO F N   1 
ATOM   18155 C CA  . PRO F 1 57  ? 20.381  111.794 15.469  1.00 38.86  ? 57  PRO F CA  1 
ATOM   18156 C C   . PRO F 1 57  ? 20.745  112.625 16.707  1.00 38.62  ? 57  PRO F C   1 
ATOM   18157 O O   . PRO F 1 57  ? 21.613  112.210 17.469  1.00 35.98  ? 57  PRO F O   1 
ATOM   18158 C CB  . PRO F 1 57  ? 20.867  112.409 14.139  1.00 38.49  ? 57  PRO F CB  1 
ATOM   18159 C CG  . PRO F 1 57  ? 19.749  112.141 13.140  1.00 39.34  ? 57  PRO F CG  1 
ATOM   18160 C CD  . PRO F 1 57  ? 18.456  111.982 13.971  1.00 38.99  ? 57  PRO F CD  1 
ATOM   18161 N N   . ASP F 1 58  ? 20.061  113.759 16.940  1.00 42.51  ? 58  ASP F N   1 
ATOM   18162 C CA  . ASP F 1 58  ? 20.473  114.709 17.978  1.00 47.59  ? 58  ASP F CA  1 
ATOM   18163 C C   . ASP F 1 58  ? 19.720  114.564 19.310  1.00 45.75  ? 58  ASP F C   1 
ATOM   18164 O O   . ASP F 1 58  ? 20.023  115.276 20.254  1.00 43.64  ? 58  ASP F O   1 
ATOM   18165 C CB  . ASP F 1 58  ? 20.407  116.138 17.460  1.00 46.56  ? 58  ASP F CB  1 
ATOM   18166 C CG  . ASP F 1 58  ? 21.400  116.424 16.345  1.00 51.90  ? 58  ASP F CG  1 
ATOM   18167 O OD1 . ASP F 1 58  ? 22.416  115.700 16.261  1.00 54.63  ? 58  ASP F OD1 1 
ATOM   18168 O OD2 . ASP F 1 58  ? 21.115  117.319 15.532  1.00 57.60  ? 58  ASP F OD2 1 
ATOM   18169 N N   . GLU F 1 59  ? 18.747  113.655 19.425  1.00 46.04  ? 59  GLU F N   1 
ATOM   18170 C CA  . GLU F 1 59  ? 18.030  113.497 20.680  1.00 43.51  ? 59  GLU F CA  1 
ATOM   18171 C C   . GLU F 1 59  ? 17.953  112.028 21.116  1.00 38.50  ? 59  GLU F C   1 
ATOM   18172 O O   . GLU F 1 59  ? 17.805  111.728 22.292  1.00 42.99  ? 59  GLU F O   1 
ATOM   18173 C CB  . GLU F 1 59  ? 16.616  114.060 20.562  1.00 45.33  ? 59  GLU F CB  1 
ATOM   18174 C CG  . GLU F 1 59  ? 16.495  115.474 20.001  1.00 46.30  ? 59  GLU F CG  1 
ATOM   18175 C CD  . GLU F 1 59  ? 15.004  115.749 19.871  1.00 52.79  ? 59  GLU F CD  1 
ATOM   18176 O OE1 . GLU F 1 59  ? 14.342  115.675 20.934  1.00 59.84  ? 59  GLU F OE1 1 
ATOM   18177 O OE2 . GLU F 1 59  ? 14.473  115.943 18.755  1.00 50.94  ? 59  GLU F OE2 1 
ATOM   18178 N N   . GLY F 1 60  ? 17.998  111.093 20.180  1.00 35.11  ? 60  GLY F N   1 
ATOM   18179 C CA  . GLY F 1 60  ? 17.930  109.687 20.531  1.00 34.38  ? 60  GLY F CA  1 
ATOM   18180 C C   . GLY F 1 60  ? 16.518  109.193 20.283  1.00 34.33  ? 60  GLY F C   1 
ATOM   18181 O O   . GLY F 1 60  ? 15.841  109.761 19.435  1.00 36.45  ? 60  GLY F O   1 
ATOM   18182 N N   . VAL F 1 61  ? 16.082  108.162 21.015  1.00 33.24  ? 61  VAL F N   1 
ATOM   18183 C CA  . VAL F 1 61  ? 14.855  107.468 20.658  1.00 33.23  ? 61  VAL F CA  1 
ATOM   18184 C C   . VAL F 1 61  ? 13.599  108.147 21.238  1.00 35.33  ? 61  VAL F C   1 
ATOM   18185 O O   . VAL F 1 61  ? 13.580  108.666 22.357  1.00 31.46  ? 61  VAL F O   1 
ATOM   18186 C CB  . VAL F 1 61  ? 14.951  105.995 21.078  1.00 32.99  ? 61  VAL F CB  1 
ATOM   18187 C CG1 . VAL F 1 61  ? 15.231  105.844 22.565  1.00 36.74  ? 61  VAL F CG1 1 
ATOM   18188 C CG2 . VAL F 1 61  ? 13.692  105.219 20.704  1.00 33.03  ? 61  VAL F CG2 1 
ATOM   18189 N N   . LYS F 1 62  ? 12.512  108.095 20.454  1.00 34.41  ? 62  LYS F N   1 
ATOM   18190 C CA  . LYS F 1 62  ? 11.172  108.363 20.952  1.00 35.29  ? 62  LYS F CA  1 
ATOM   18191 C C   . LYS F 1 62  ? 10.280  107.155 20.669  1.00 32.64  ? 62  LYS F C   1 
ATOM   18192 O O   . LYS F 1 62  ? 10.273  106.630 19.569  1.00 33.36  ? 62  LYS F O   1 
ATOM   18193 C CB  . LYS F 1 62  ? 10.577  109.637 20.339  1.00 37.91  ? 62  LYS F CB  1 
ATOM   18194 C CG  . LYS F 1 62  ? 11.487  110.874 20.373  1.00 39.24  ? 62  LYS F CG  1 
ATOM   18195 C CD  . LYS F 1 62  ? 10.714  112.184 20.451  1.00 41.76  ? 62  LYS F CD  1 
ATOM   18196 C CE  . LYS F 1 62  ? 11.531  113.379 20.812  1.00 44.22  ? 62  LYS F CE  1 
ATOM   18197 N NZ  . LYS F 1 62  ? 12.038  113.968 19.577  1.00 52.82  ? 62  LYS F NZ  1 
ATOM   18198 N N   . PHE F 1 63  ? 9.553   106.700 21.693  1.00 34.11  ? 63  PHE F N   1 
ATOM   18199 C CA  . PHE F 1 63  ? 8.548   105.667 21.538  1.00 34.89  ? 63  PHE F CA  1 
ATOM   18200 C C   . PHE F 1 63  ? 7.194   106.324 21.299  1.00 35.62  ? 63  PHE F C   1 
ATOM   18201 O O   . PHE F 1 63  ? 6.643   106.928 22.217  1.00 34.26  ? 63  PHE F O   1 
ATOM   18202 C CB  . PHE F 1 63  ? 8.497   104.839 22.817  1.00 33.62  ? 63  PHE F CB  1 
ATOM   18203 C CG  . PHE F 1 63  ? 9.836   104.217 23.149  1.00 33.57  ? 63  PHE F CG  1 
ATOM   18204 C CD1 . PHE F 1 63  ? 10.408  103.278 22.305  1.00 35.30  ? 63  PHE F CD1 1 
ATOM   18205 C CD2 . PHE F 1 63  ? 10.514  104.571 24.302  1.00 34.45  ? 63  PHE F CD2 1 
ATOM   18206 C CE1 . PHE F 1 63  ? 11.621  102.692 22.623  1.00 33.80  ? 63  PHE F CE1 1 
ATOM   18207 C CE2 . PHE F 1 63  ? 11.737  103.997 24.599  1.00 32.33  ? 63  PHE F CE2 1 
ATOM   18208 C CZ  . PHE F 1 63  ? 12.275  103.052 23.770  1.00 31.85  ? 63  PHE F CZ  1 
ATOM   18209 N N   . ARG F 1 64  ? 6.690   106.223 20.062  1.00 32.75  ? 64  ARG F N   1 
ATOM   18210 C CA  . ARG F 1 64  ? 5.399   106.794 19.694  1.00 32.91  ? 64  ARG F CA  1 
ATOM   18211 C C   . ARG F 1 64  ? 5.343   108.265 20.086  1.00 32.86  ? 64  ARG F C   1 
ATOM   18212 O O   . ARG F 1 64  ? 4.312   108.727 20.577  1.00 33.12  ? 64  ARG F O   1 
ATOM   18213 C CB  . ARG F 1 64  ? 4.218   106.057 20.341  1.00 29.62  ? 64  ARG F CB  1 
ATOM   18214 C CG  . ARG F 1 64  ? 3.995   104.652 19.802  1.00 30.55  ? 64  ARG F CG  1 
ATOM   18215 C CD  . ARG F 1 64  ? 3.491   104.664 18.370  1.00 30.13  ? 64  ARG F CD  1 
ATOM   18216 N NE  . ARG F 1 64  ? 2.961   103.357 17.971  1.00 29.13  ? 64  ARG F NE  1 
ATOM   18217 C CZ  . ARG F 1 64  ? 2.356   103.098 16.834  1.00 29.71  ? 64  ARG F CZ  1 
ATOM   18218 N NH1 . ARG F 1 64  ? 2.020   104.089 16.033  1.00 34.79  ? 64  ARG F NH1 1 
ATOM   18219 N NH2 . ARG F 1 64  ? 2.074   101.856 16.487  1.00 30.79  ? 64  ARG F NH2 1 
ATOM   18220 N N   . GLY F 1 65  ? 6.478   108.956 19.913  1.00 32.95  ? 65  GLY F N   1 
ATOM   18221 C CA  . GLY F 1 65  ? 6.569   110.387 20.131  1.00 34.60  ? 65  GLY F CA  1 
ATOM   18222 C C   . GLY F 1 65  ? 7.107   110.763 21.513  1.00 37.33  ? 65  GLY F C   1 
ATOM   18223 O O   . GLY F 1 65  ? 7.575   111.883 21.694  1.00 40.19  ? 65  GLY F O   1 
ATOM   18224 N N   . TYR F 1 66  ? 7.029   109.841 22.488  1.00 40.04  ? 66  TYR F N   1 
ATOM   18225 C CA  . TYR F 1 66  ? 7.414   110.112 23.873  1.00 35.80  ? 66  TYR F CA  1 
ATOM   18226 C C   . TYR F 1 66  ? 8.897   109.804 24.064  1.00 34.89  ? 66  TYR F C   1 
ATOM   18227 O O   . TYR F 1 66  ? 9.373   108.761 23.606  1.00 37.31  ? 66  TYR F O   1 
ATOM   18228 C CB  . TYR F 1 66  ? 6.572   109.270 24.848  1.00 34.58  ? 66  TYR F CB  1 
ATOM   18229 C CG  . TYR F 1 66  ? 5.070   109.531 24.784  1.00 33.89  ? 66  TYR F CG  1 
ATOM   18230 C CD1 . TYR F 1 66  ? 4.239   108.815 23.912  1.00 33.69  ? 66  TYR F CD1 1 
ATOM   18231 C CD2 . TYR F 1 66  ? 4.483   110.534 25.554  1.00 34.88  ? 66  TYR F CD2 1 
ATOM   18232 C CE1 . TYR F 1 66  ? 2.876   109.070 23.833  1.00 30.67  ? 66  TYR F CE1 1 
ATOM   18233 C CE2 . TYR F 1 66  ? 3.126   110.814 25.459  1.00 35.87  ? 66  TYR F CE2 1 
ATOM   18234 C CZ  . TYR F 1 66  ? 2.321   110.076 24.603  1.00 31.77  ? 66  TYR F CZ  1 
ATOM   18235 O OH  . TYR F 1 66  ? 0.986   110.352 24.575  1.00 32.07  ? 66  TYR F OH  1 
ATOM   18236 N N   . THR F 1 67  ? 9.597   110.680 24.800  1.00 32.53  ? 67  THR F N   1 
ATOM   18237 C CA  . THR F 1 67  ? 10.980  110.431 25.206  1.00 31.15  ? 67  THR F CA  1 
ATOM   18238 C C   . THR F 1 67  ? 11.028  109.420 26.361  1.00 30.28  ? 67  THR F C   1 
ATOM   18239 O O   . THR F 1 67  ? 10.027  109.077 26.989  1.00 33.39  ? 67  THR F O   1 
ATOM   18240 C CB  . THR F 1 67  ? 11.678  111.734 25.624  1.00 29.08  ? 67  THR F CB  1 
ATOM   18241 O OG1 . THR F 1 67  ? 11.162  112.046 26.916  1.00 27.03  ? 67  THR F OG1 1 
ATOM   18242 C CG2 . THR F 1 67  ? 11.487  112.884 24.650  1.00 27.06  ? 67  THR F CG2 1 
ATOM   18243 N N   . ILE F 1 68  ? 12.237  108.977 26.688  1.00 32.30  ? 68  ILE F N   1 
ATOM   18244 C CA  . ILE F 1 68  ? 12.474  108.096 27.824  1.00 33.79  ? 68  ILE F CA  1 
ATOM   18245 C C   . ILE F 1 68  ? 12.129  108.815 29.138  1.00 33.63  ? 68  ILE F C   1 
ATOM   18246 O O   . ILE F 1 68  ? 11.345  108.284 29.926  1.00 30.44  ? 68  ILE F O   1 
ATOM   18247 C CB  . ILE F 1 68  ? 13.920  107.549 27.756  1.00 33.59  ? 68  ILE F CB  1 
ATOM   18248 C CG1 . ILE F 1 68  ? 14.000  106.448 26.676  1.00 32.55  ? 68  ILE F CG1 1 
ATOM   18249 C CG2 . ILE F 1 68  ? 14.442  107.077 29.122  1.00 30.87  ? 68  ILE F CG2 1 
ATOM   18250 C CD1 . ILE F 1 68  ? 15.408  106.138 26.214  1.00 34.62  ? 68  ILE F CD1 1 
ATOM   18251 N N   . PRO F 1 69  ? 12.667  110.031 29.419  1.00 35.45  ? 69  PRO F N   1 
ATOM   18252 C CA  . PRO F 1 69  ? 12.306  110.770 30.622  1.00 35.01  ? 69  PRO F CA  1 
ATOM   18253 C C   . PRO F 1 69  ? 10.797  110.886 30.739  1.00 35.98  ? 69  PRO F C   1 
ATOM   18254 O O   . PRO F 1 69  ? 10.242  110.597 31.789  1.00 40.96  ? 69  PRO F O   1 
ATOM   18255 C CB  . PRO F 1 69  ? 12.996  112.130 30.427  1.00 36.19  ? 69  PRO F CB  1 
ATOM   18256 C CG  . PRO F 1 69  ? 14.225  111.781 29.625  1.00 37.34  ? 69  PRO F CG  1 
ATOM   18257 C CD  . PRO F 1 69  ? 13.669  110.770 28.625  1.00 40.20  ? 69  PRO F CD  1 
ATOM   18258 N N   . GLU F 1 70  ? 10.135  111.271 29.651  1.00 34.79  ? 70  GLU F N   1 
ATOM   18259 C CA  . GLU F 1 70  ? 8.692   111.417 29.675  1.00 35.06  ? 70  GLU F CA  1 
ATOM   18260 C C   . GLU F 1 70  ? 7.988   110.161 30.197  1.00 32.94  ? 70  GLU F C   1 
ATOM   18261 O O   . GLU F 1 70  ? 6.971   110.294 30.869  1.00 29.64  ? 70  GLU F O   1 
ATOM   18262 C CB  . GLU F 1 70  ? 8.183   111.820 28.296  1.00 40.20  ? 70  GLU F CB  1 
ATOM   18263 C CG  . GLU F 1 70  ? 8.378   113.301 27.983  1.00 42.88  ? 70  GLU F CG  1 
ATOM   18264 C CD  . GLU F 1 70  ? 7.836   113.658 26.618  1.00 40.30  ? 70  GLU F CD  1 
ATOM   18265 O OE1 . GLU F 1 70  ? 6.952   114.520 26.576  1.00 46.11  ? 70  GLU F OE1 1 
ATOM   18266 O OE2 . GLU F 1 70  ? 8.261   113.039 25.630  1.00 40.80  ? 70  GLU F OE2 1 
ATOM   18267 N N   . LEU F 1 71  ? 8.491   108.959 29.878  1.00 32.11  ? 71  LEU F N   1 
ATOM   18268 C CA  . LEU F 1 71  ? 7.772   107.729 30.198  1.00 30.56  ? 71  LEU F CA  1 
ATOM   18269 C C   . LEU F 1 71  ? 8.239   107.119 31.516  1.00 32.08  ? 71  LEU F C   1 
ATOM   18270 O O   . LEU F 1 71  ? 7.590   106.211 32.052  1.00 33.23  ? 71  LEU F O   1 
ATOM   18271 C CB  . LEU F 1 71  ? 7.971   106.719 29.072  1.00 29.26  ? 71  LEU F CB  1 
ATOM   18272 C CG  . LEU F 1 71  ? 7.311   107.061 27.735  1.00 31.07  ? 71  LEU F CG  1 
ATOM   18273 C CD1 . LEU F 1 71  ? 7.725   106.029 26.711  1.00 33.39  ? 71  LEU F CD1 1 
ATOM   18274 C CD2 . LEU F 1 71  ? 5.806   107.127 27.807  1.00 30.98  ? 71  LEU F CD2 1 
ATOM   18275 N N   . ARG F 1 72  ? 9.414   107.564 31.974  1.00 34.66  ? 72  ARG F N   1 
ATOM   18276 C CA  . ARG F 1 72  ? 10.098  106.991 33.122  1.00 33.91  ? 72  ARG F CA  1 
ATOM   18277 C C   . ARG F 1 72  ? 9.813   107.824 34.380  1.00 35.90  ? 72  ARG F C   1 
ATOM   18278 O O   . ARG F 1 72  ? 9.570   107.279 35.443  1.00 36.83  ? 72  ARG F O   1 
ATOM   18279 C CB  . ARG F 1 72  ? 11.587  106.869 32.773  1.00 31.92  ? 72  ARG F CB  1 
ATOM   18280 C CG  . ARG F 1 72  ? 12.392  106.369 33.962  1.00 33.74  ? 72  ARG F CG  1 
ATOM   18281 C CD  . ARG F 1 72  ? 13.700  105.717 33.611  1.00 36.10  ? 72  ARG F CD  1 
ATOM   18282 N NE  . ARG F 1 72  ? 14.374  105.271 34.837  1.00 37.53  ? 72  ARG F NE  1 
ATOM   18283 C CZ  . ARG F 1 72  ? 15.370  105.920 35.437  1.00 40.39  ? 72  ARG F CZ  1 
ATOM   18284 N NH1 . ARG F 1 72  ? 15.721  107.125 35.014  1.00 39.03  ? 72  ARG F NH1 1 
ATOM   18285 N NH2 . ARG F 1 72  ? 16.000  105.378 36.470  1.00 41.38  ? 72  ARG F NH2 1 
ATOM   18286 N N   . GLU F 1 73  ? 9.825   109.154 34.258  1.00 42.45  ? 73  GLU F N   1 
ATOM   18287 C CA  . GLU F 1 73  ? 9.561   110.068 35.363  1.00 48.57  ? 73  GLU F CA  1 
ATOM   18288 C C   . GLU F 1 73  ? 8.470   111.067 34.969  1.00 55.04  ? 73  GLU F C   1 
ATOM   18289 O O   . GLU F 1 73  ? 7.599   111.370 35.782  1.00 48.16  ? 73  GLU F O   1 
ATOM   18290 C CB  . GLU F 1 73  ? 10.849  110.772 35.799  1.00 49.37  ? 73  GLU F CB  1 
ATOM   18291 C CG  . GLU F 1 73  ? 11.929  110.768 34.725  1.00 50.24  ? 73  GLU F CG  1 
ATOM   18292 C CD  . GLU F 1 73  ? 13.345  111.093 35.127  1.00 50.71  ? 73  GLU F CD  1 
ATOM   18293 O OE1 . GLU F 1 73  ? 14.091  111.711 34.332  1.00 53.10  ? 73  GLU F OE1 1 
ATOM   18294 O OE2 . GLU F 1 73  ? 13.700  110.688 36.240  1.00 62.77  ? 73  GLU F OE2 1 
ATOM   18295 N N   . GLY F 1 74  ? 8.506   111.509 33.701  1.00 61.92  ? 74  GLY F N   1 
ATOM   18296 C CA  . GLY F 1 74  ? 7.949   112.774 33.259  1.00 57.66  ? 74  GLY F CA  1 
ATOM   18297 C C   . GLY F 1 74  ? 6.434   112.768 33.367  1.00 66.82  ? 74  GLY F C   1 
ATOM   18298 O O   . GLY F 1 74  ? 5.858   111.894 34.016  1.00 80.21  ? 74  GLY F O   1 
ATOM   18299 N N   . PRO F 1 75  ? 5.742   113.722 32.704  1.00 67.53  ? 75  PRO F N   1 
ATOM   18300 C CA  . PRO F 1 75  ? 4.295   113.867 32.882  1.00 65.76  ? 75  PRO F CA  1 
ATOM   18301 C C   . PRO F 1 75  ? 3.496   112.634 32.443  1.00 61.80  ? 75  PRO F C   1 
ATOM   18302 O O   . PRO F 1 75  ? 2.365   112.449 32.893  1.00 60.46  ? 75  PRO F O   1 
ATOM   18303 C CB  . PRO F 1 75  ? 3.984   115.133 32.042  1.00 65.90  ? 75  PRO F CB  1 
ATOM   18304 C CG  . PRO F 1 75  ? 5.083   115.171 30.995  1.00 63.79  ? 75  PRO F CG  1 
ATOM   18305 C CD  . PRO F 1 75  ? 6.311   114.667 31.723  1.00 63.64  ? 75  PRO F CD  1 
ATOM   18306 N N   . HIS F 1 76  ? 4.112   111.790 31.593  1.00 53.13  ? 76  HIS F N   1 
ATOM   18307 C CA  . HIS F 1 76  ? 3.458   110.639 30.983  1.00 49.45  ? 76  HIS F CA  1 
ATOM   18308 C C   . HIS F 1 76  ? 4.082   109.327 31.467  1.00 41.72  ? 76  HIS F C   1 
ATOM   18309 O O   . HIS F 1 76  ? 4.343   108.437 30.667  1.00 48.46  ? 76  HIS F O   1 
ATOM   18310 C CB  . HIS F 1 76  ? 3.564   110.715 29.451  1.00 48.81  ? 76  HIS F CB  1 
ATOM   18311 C CG  . HIS F 1 76  ? 2.956   111.937 28.834  1.00 50.45  ? 76  HIS F CG  1 
ATOM   18312 N ND1 . HIS F 1 76  ? 1.602   112.209 28.888  1.00 47.22  ? 76  HIS F ND1 1 
ATOM   18313 C CD2 . HIS F 1 76  ? 3.527   112.958 28.158  1.00 47.22  ? 76  HIS F CD2 1 
ATOM   18314 C CE1 . HIS F 1 76  ? 1.369   113.349 28.253  1.00 47.90  ? 76  HIS F CE1 1 
ATOM   18315 N NE2 . HIS F 1 76  ? 2.525   113.821 27.806  1.00 47.28  ? 76  HIS F NE2 1 
ATOM   18316 N N   . LYS F 1 77  ? 4.288   109.198 32.779  1.00 38.95  ? 77  LYS F N   1 
ATOM   18317 C CA  . LYS F 1 77  ? 5.004   108.072 33.361  1.00 37.28  ? 77  LYS F CA  1 
ATOM   18318 C C   . LYS F 1 77  ? 4.177   106.798 33.260  1.00 36.04  ? 77  LYS F C   1 
ATOM   18319 O O   . LYS F 1 77  ? 3.010   106.752 33.654  1.00 36.76  ? 77  LYS F O   1 
ATOM   18320 C CB  . LYS F 1 77  ? 5.323   108.339 34.832  1.00 41.44  ? 77  LYS F CB  1 
ATOM   18321 C CG  . LYS F 1 77  ? 6.119   107.243 35.521  1.00 47.02  ? 77  LYS F CG  1 
ATOM   18322 C CD  . LYS F 1 77  ? 6.539   107.632 36.933  1.00 46.47  ? 77  LYS F CD  1 
ATOM   18323 C CE  . LYS F 1 77  ? 7.150   106.528 37.736  1.00 46.16  ? 77  LYS F CE  1 
ATOM   18324 N NZ  . LYS F 1 77  ? 8.555   106.327 37.396  1.00 44.33  ? 77  LYS F NZ  1 
ATOM   18325 N N   . LEU F 1 78  ? 4.808   105.751 32.730  1.00 35.89  ? 78  LEU F N   1 
ATOM   18326 C CA  . LEU F 1 78  ? 4.130   104.484 32.519  1.00 33.12  ? 78  LEU F CA  1 
ATOM   18327 C C   . LEU F 1 78  ? 3.892   103.825 33.869  1.00 31.32  ? 78  LEU F C   1 
ATOM   18328 O O   . LEU F 1 78  ? 4.500   104.180 34.873  1.00 29.16  ? 78  LEU F O   1 
ATOM   18329 C CB  . LEU F 1 78  ? 4.926   103.555 31.599  1.00 34.56  ? 78  LEU F CB  1 
ATOM   18330 C CG  . LEU F 1 78  ? 5.054   103.976 30.129  1.00 34.69  ? 78  LEU F CG  1 
ATOM   18331 C CD1 . LEU F 1 78  ? 6.095   103.117 29.401  1.00 32.97  ? 78  LEU F CD1 1 
ATOM   18332 C CD2 . LEU F 1 78  ? 3.679   103.890 29.454  1.00 33.30  ? 78  LEU F CD2 1 
ATOM   18333 N N   . PRO F 1 79  ? 2.958   102.860 33.949  1.00 32.12  ? 79  PRO F N   1 
ATOM   18334 C CA  . PRO F 1 79  ? 2.788   102.105 35.181  1.00 30.32  ? 79  PRO F CA  1 
ATOM   18335 C C   . PRO F 1 79  ? 4.026   101.288 35.551  1.00 35.82  ? 79  PRO F C   1 
ATOM   18336 O O   . PRO F 1 79  ? 4.708   100.747 34.669  1.00 33.71  ? 79  PRO F O   1 
ATOM   18337 C CB  . PRO F 1 79  ? 1.581   101.239 34.854  1.00 29.73  ? 79  PRO F CB  1 
ATOM   18338 C CG  . PRO F 1 79  ? 0.850   101.997 33.792  1.00 29.39  ? 79  PRO F CG  1 
ATOM   18339 C CD  . PRO F 1 79  ? 1.964   102.526 32.913  1.00 29.98  ? 79  PRO F CD  1 
ATOM   18340 N N   . THR F 1 80  ? 4.274   101.232 36.875  1.00 36.14  ? 80  THR F N   1 
ATOM   18341 C CA  . THR F 1 80  ? 5.355   100.478 37.491  1.00 35.32  ? 80  THR F CA  1 
ATOM   18342 C C   . THR F 1 80  ? 4.776   99.215  38.127  1.00 32.68  ? 80  THR F C   1 
ATOM   18343 O O   . THR F 1 80  ? 3.559   99.031  38.133  1.00 32.92  ? 80  THR F O   1 
ATOM   18344 C CB  . THR F 1 80  ? 6.038   101.377 38.534  1.00 33.59  ? 80  THR F CB  1 
ATOM   18345 O OG1 . THR F 1 80  ? 5.159   101.551 39.631  1.00 32.06  ? 80  THR F OG1 1 
ATOM   18346 C CG2 . THR F 1 80  ? 6.307   102.795 38.075  1.00 30.22  ? 80  THR F CG2 1 
ATOM   18347 N N   . ALA F 1 81  ? 5.646   98.367  38.702  1.00 32.66  ? 81  ALA F N   1 
ATOM   18348 C CA  . ALA F 1 81  ? 5.225   97.384  39.700  1.00 35.27  ? 81  ALA F CA  1 
ATOM   18349 C C   . ALA F 1 81  ? 4.725   98.075  40.977  1.00 38.44  ? 81  ALA F C   1 
ATOM   18350 O O   . ALA F 1 81  ? 5.047   99.236  41.218  1.00 42.52  ? 81  ALA F O   1 
ATOM   18351 C CB  . ALA F 1 81  ? 6.377   96.489  40.044  1.00 35.94  ? 81  ALA F CB  1 
ATOM   18352 N N   . GLU F 1 82  ? 3.946   97.360  41.801  1.00 39.24  ? 82  GLU F N   1 
ATOM   18353 C CA  . GLU F 1 82  ? 3.564   97.804  43.137  1.00 42.46  ? 82  GLU F CA  1 
ATOM   18354 C C   . GLU F 1 82  ? 4.781   98.236  43.956  1.00 40.41  ? 82  GLU F C   1 
ATOM   18355 O O   . GLU F 1 82  ? 5.622   97.408  44.278  1.00 42.15  ? 82  GLU F O   1 
ATOM   18356 C CB  . GLU F 1 82  ? 2.930   96.671  43.951  1.00 51.48  ? 82  GLU F CB  1 
ATOM   18357 C CG  . GLU F 1 82  ? 1.409   96.739  44.042  1.00 64.48  ? 82  GLU F CG  1 
ATOM   18358 C CD  . GLU F 1 82  ? 0.879   98.024  44.660  1.00 73.85  ? 82  GLU F CD  1 
ATOM   18359 O OE1 . GLU F 1 82  ? -0.029  98.629  44.045  1.00 85.40  ? 82  GLU F OE1 1 
ATOM   18360 O OE2 . GLU F 1 82  ? 1.376   98.438  45.733  1.00 69.54  ? 82  GLU F OE2 1 
ATOM   18361 N N   . GLY F 1 83  ? 4.839   99.519  44.341  1.00 36.38  ? 83  GLY F N   1 
ATOM   18362 C CA  . GLY F 1 83  ? 5.923   100.028 45.162  1.00 35.23  ? 83  GLY F CA  1 
ATOM   18363 C C   . GLY F 1 83  ? 7.183   100.307 44.341  1.00 38.72  ? 83  GLY F C   1 
ATOM   18364 O O   . GLY F 1 83  ? 8.236   100.644 44.897  1.00 37.52  ? 83  GLY F O   1 
ATOM   18365 N N   . GLY F 1 84  ? 7.052   100.193 43.005  1.00 37.72  ? 84  GLY F N   1 
ATOM   18366 C CA  . GLY F 1 84  ? 8.159   100.347 42.076  1.00 34.83  ? 84  GLY F CA  1 
ATOM   18367 C C   . GLY F 1 84  ? 8.354   101.798 41.641  1.00 34.35  ? 84  GLY F C   1 
ATOM   18368 O O   . GLY F 1 84  ? 7.536   102.648 41.953  1.00 34.07  ? 84  GLY F O   1 
ATOM   18369 N N   . PHE F 1 85  ? 9.483   102.059 40.962  1.00 35.53  ? 85  PHE F N   1 
ATOM   18370 C CA  . PHE F 1 85  ? 9.732   103.306 40.259  1.00 35.53  ? 85  PHE F CA  1 
ATOM   18371 C C   . PHE F 1 85  ? 9.892   103.057 38.750  1.00 40.52  ? 85  PHE F C   1 
ATOM   18372 O O   . PHE F 1 85  ? 9.377   103.824 37.924  1.00 37.97  ? 85  PHE F O   1 
ATOM   18373 C CB  . PHE F 1 85  ? 11.009  103.958 40.795  1.00 35.14  ? 85  PHE F CB  1 
ATOM   18374 C CG  . PHE F 1 85  ? 11.370  105.245 40.064  1.00 37.28  ? 85  PHE F CG  1 
ATOM   18375 C CD1 . PHE F 1 85  ? 10.771  106.455 40.410  1.00 38.77  ? 85  PHE F CD1 1 
ATOM   18376 C CD2 . PHE F 1 85  ? 12.277  105.244 39.007  1.00 39.30  ? 85  PHE F CD2 1 
ATOM   18377 C CE1 . PHE F 1 85  ? 11.085  107.633 39.736  1.00 38.43  ? 85  PHE F CE1 1 
ATOM   18378 C CE2 . PHE F 1 85  ? 12.591  106.425 38.342  1.00 40.12  ? 85  PHE F CE2 1 
ATOM   18379 C CZ  . PHE F 1 85  ? 11.998  107.616 38.712  1.00 38.79  ? 85  PHE F CZ  1 
ATOM   18380 N N   . GLU F 1 86  ? 10.633  101.996 38.385  1.00 38.57  ? 86  GLU F N   1 
ATOM   18381 C CA  . GLU F 1 86  ? 11.018  101.777 36.998  1.00 37.29  ? 86  GLU F CA  1 
ATOM   18382 C C   . GLU F 1 86  ? 9.783   101.358 36.201  1.00 31.06  ? 86  GLU F C   1 
ATOM   18383 O O   . GLU F 1 86  ? 8.932   100.641 36.708  1.00 28.52  ? 86  GLU F O   1 
ATOM   18384 C CB  . GLU F 1 86  ? 12.174  100.778 36.889  1.00 37.57  ? 86  GLU F CB  1 
ATOM   18385 C CG  . GLU F 1 86  ? 13.468  101.225 37.569  1.00 33.84  ? 86  GLU F CG  1 
ATOM   18386 C CD  . GLU F 1 86  ? 14.056  102.527 37.058  1.00 32.32  ? 86  GLU F CD  1 
ATOM   18387 O OE1 . GLU F 1 86  ? 14.915  103.123 37.736  1.00 31.08  ? 86  GLU F OE1 1 
ATOM   18388 O OE2 . GLU F 1 86  ? 13.644  102.958 35.983  1.00 30.00  ? 86  GLU F OE2 1 
ATOM   18389 N N   . PRO F 1 87  ? 9.619   101.871 34.964  1.00 29.80  ? 87  PRO F N   1 
ATOM   18390 C CA  . PRO F 1 87  ? 8.483   101.514 34.106  1.00 31.05  ? 87  PRO F CA  1 
ATOM   18391 C C   . PRO F 1 87  ? 8.481   100.069 33.616  1.00 30.14  ? 87  PRO F C   1 
ATOM   18392 O O   . PRO F 1 87  ? 9.521   99.500  33.276  1.00 32.77  ? 87  PRO F O   1 
ATOM   18393 C CB  . PRO F 1 87  ? 8.644   102.479 32.926  1.00 32.73  ? 87  PRO F CB  1 
ATOM   18394 C CG  . PRO F 1 87  ? 10.140  102.733 32.858  1.00 30.96  ? 87  PRO F CG  1 
ATOM   18395 C CD  . PRO F 1 87  ? 10.527  102.844 34.329  1.00 32.51  ? 87  PRO F CD  1 
ATOM   18396 N N   . LEU F 1 88  ? 7.300   99.473  33.557  1.00 27.08  ? 88  LEU F N   1 
ATOM   18397 C CA  . LEU F 1 88  ? 7.233   98.081  33.170  1.00 28.16  ? 88  LEU F CA  1 
ATOM   18398 C C   . LEU F 1 88  ? 7.247   97.976  31.647  1.00 28.22  ? 88  LEU F C   1 
ATOM   18399 O O   . LEU F 1 88  ? 6.543   98.710  30.944  1.00 27.62  ? 88  LEU F O   1 
ATOM   18400 C CB  . LEU F 1 88  ? 5.989   97.413  33.740  1.00 29.97  ? 88  LEU F CB  1 
ATOM   18401 C CG  . LEU F 1 88  ? 5.877   97.284  35.260  1.00 32.01  ? 88  LEU F CG  1 
ATOM   18402 C CD1 . LEU F 1 88  ? 4.730   96.313  35.511  1.00 32.61  ? 88  LEU F CD1 1 
ATOM   18403 C CD2 . LEU F 1 88  ? 7.129   96.806  35.961  1.00 33.28  ? 88  LEU F CD2 1 
ATOM   18404 N N   . PRO F 1 89  ? 8.006   97.012  31.087  1.00 27.05  ? 89  PRO F N   1 
ATOM   18405 C CA  . PRO F 1 89  ? 7.991   96.786  29.643  1.00 27.92  ? 89  PRO F CA  1 
ATOM   18406 C C   . PRO F 1 89  ? 6.607   96.457  29.086  1.00 27.95  ? 89  PRO F C   1 
ATOM   18407 O O   . PRO F 1 89  ? 6.311   96.822  27.954  1.00 27.99  ? 89  PRO F O   1 
ATOM   18408 C CB  . PRO F 1 89  ? 8.986   95.625  29.469  1.00 26.23  ? 89  PRO F CB  1 
ATOM   18409 C CG  . PRO F 1 89  ? 9.026   94.954  30.793  1.00 25.10  ? 89  PRO F CG  1 
ATOM   18410 C CD  . PRO F 1 89  ? 8.873   96.068  31.800  1.00 24.63  ? 89  PRO F CD  1 
ATOM   18411 N N   . GLU F 1 90  ? 5.768   95.782  29.888  1.00 27.85  ? 90  GLU F N   1 
ATOM   18412 C CA  . GLU F 1 90  ? 4.413   95.423  29.478  1.00 28.77  ? 90  GLU F CA  1 
ATOM   18413 C C   . GLU F 1 90  ? 3.636   96.658  28.986  1.00 28.27  ? 90  GLU F C   1 
ATOM   18414 O O   . GLU F 1 90  ? 2.934   96.619  27.978  1.00 27.64  ? 90  GLU F O   1 
ATOM   18415 C CB  . GLU F 1 90  ? 3.644   94.694  30.590  1.00 28.60  ? 90  GLU F CB  1 
ATOM   18416 C CG  . GLU F 1 90  ? 4.245   93.359  31.047  1.00 29.00  ? 90  GLU F CG  1 
ATOM   18417 C CD  . GLU F 1 90  ? 5.171   93.394  32.274  1.00 28.61  ? 90  GLU F CD  1 
ATOM   18418 O OE1 . GLU F 1 90  ? 4.830   92.657  33.218  1.00 25.20  ? 90  GLU F OE1 1 
ATOM   18419 O OE2 . GLU F 1 90  ? 6.210   94.110  32.321  1.00 27.95  ? 90  GLU F OE2 1 
ATOM   18420 N N   . GLY F 1 91  ? 3.778   97.781  29.683  1.00 31.48  ? 91  GLY F N   1 
ATOM   18421 C CA  . GLY F 1 91  ? 3.083   99.005  29.308  1.00 34.17  ? 91  GLY F CA  1 
ATOM   18422 C C   . GLY F 1 91  ? 3.683   99.690  28.078  1.00 33.17  ? 91  GLY F C   1 
ATOM   18423 O O   . GLY F 1 91  ? 2.946   100.247 27.273  1.00 33.48  ? 91  GLY F O   1 
ATOM   18424 N N   . LEU F 1 92  ? 5.014   99.673  27.968  1.00 31.76  ? 92  LEU F N   1 
ATOM   18425 C CA  . LEU F 1 92  ? 5.707   100.193 26.805  1.00 31.52  ? 92  LEU F CA  1 
ATOM   18426 C C   . LEU F 1 92  ? 5.257   99.438  25.559  1.00 32.35  ? 92  LEU F C   1 
ATOM   18427 O O   . LEU F 1 92  ? 4.983   100.047 24.535  1.00 33.30  ? 92  LEU F O   1 
ATOM   18428 C CB  . LEU F 1 92  ? 7.209   100.052 27.000  1.00 31.17  ? 92  LEU F CB  1 
ATOM   18429 C CG  . LEU F 1 92  ? 8.066   100.484 25.815  1.00 31.79  ? 92  LEU F CG  1 
ATOM   18430 C CD1 . LEU F 1 92  ? 7.863   101.946 25.516  1.00 31.58  ? 92  LEU F CD1 1 
ATOM   18431 C CD2 . LEU F 1 92  ? 9.509   100.213 26.114  1.00 32.98  ? 92  LEU F CD2 1 
ATOM   18432 N N   . TRP F 1 93  ? 5.159   98.113  25.659  1.00 30.21  ? 93  TRP F N   1 
ATOM   18433 C CA  . TRP F 1 93  ? 4.677   97.312  24.552  1.00 29.07  ? 93  TRP F CA  1 
ATOM   18434 C C   . TRP F 1 93  ? 3.290   97.766  24.093  1.00 32.09  ? 93  TRP F C   1 
ATOM   18435 O O   . TRP F 1 93  ? 3.035   97.847  22.892  1.00 30.36  ? 93  TRP F O   1 
ATOM   18436 C CB  . TRP F 1 93  ? 4.606   95.847  24.974  1.00 27.07  ? 93  TRP F CB  1 
ATOM   18437 C CG  . TRP F 1 93  ? 4.504   94.891  23.823  1.00 25.68  ? 93  TRP F CG  1 
ATOM   18438 C CD1 . TRP F 1 93  ? 5.305   94.853  22.722  1.00 25.68  ? 93  TRP F CD1 1 
ATOM   18439 C CD2 . TRP F 1 93  ? 3.559   93.820  23.673  1.00 24.92  ? 93  TRP F CD2 1 
ATOM   18440 N NE1 . TRP F 1 93  ? 4.942   93.809  21.914  1.00 26.05  ? 93  TRP F NE1 1 
ATOM   18441 C CE2 . TRP F 1 93  ? 3.882   93.158  22.473  1.00 25.28  ? 93  TRP F CE2 1 
ATOM   18442 C CE3 . TRP F 1 93  ? 2.496   93.356  24.436  1.00 24.06  ? 93  TRP F CE3 1 
ATOM   18443 C CZ2 . TRP F 1 93  ? 3.187   92.048  22.023  1.00 25.29  ? 93  TRP F CZ2 1 
ATOM   18444 C CZ3 . TRP F 1 93  ? 1.820   92.252  24.001  1.00 26.95  ? 93  TRP F CZ3 1 
ATOM   18445 C CH2 . TRP F 1 93  ? 2.158   91.609  22.810  1.00 27.71  ? 93  TRP F CH2 1 
ATOM   18446 N N   . TYR F 1 94  ? 2.377   98.001  25.052  1.00 33.27  ? 94  TYR F N   1 
ATOM   18447 C CA  . TYR F 1 94  ? 1.027   98.443  24.723  1.00 32.68  ? 94  TYR F CA  1 
ATOM   18448 C C   . TYR F 1 94  ? 1.069   99.769  23.962  1.00 30.98  ? 94  TYR F C   1 
ATOM   18449 O O   . TYR F 1 94  ? 0.322   99.944  22.998  1.00 28.02  ? 94  TYR F O   1 
ATOM   18450 C CB  . TYR F 1 94  ? 0.205   98.564  26.000  1.00 33.17  ? 94  TYR F CB  1 
ATOM   18451 C CG  . TYR F 1 94  ? -1.236  98.983  25.783  1.00 30.81  ? 94  TYR F CG  1 
ATOM   18452 C CD1 . TYR F 1 94  ? -1.548  100.295 25.481  1.00 31.17  ? 94  TYR F CD1 1 
ATOM   18453 C CD2 . TYR F 1 94  ? -2.280  98.079  25.939  1.00 33.30  ? 94  TYR F CD2 1 
ATOM   18454 C CE1 . TYR F 1 94  ? -2.860  100.700 25.308  1.00 33.01  ? 94  TYR F CE1 1 
ATOM   18455 C CE2 . TYR F 1 94  ? -3.603  98.471  25.781  1.00 34.06  ? 94  TYR F CE2 1 
ATOM   18456 C CZ  . TYR F 1 94  ? -3.889  99.789  25.463  1.00 34.69  ? 94  TYR F CZ  1 
ATOM   18457 O OH  . TYR F 1 94  ? -5.173  100.217 25.298  1.00 39.74  ? 94  TYR F OH  1 
ATOM   18458 N N   . LEU F 1 95  ? 1.973   100.669 24.378  1.00 26.65  ? 95  LEU F N   1 
ATOM   18459 C CA  . LEU F 1 95  ? 2.192   101.922 23.678  1.00 27.85  ? 95  LEU F CA  1 
ATOM   18460 C C   . LEU F 1 95  ? 2.672   101.669 22.239  1.00 29.95  ? 95  LEU F C   1 
ATOM   18461 O O   . LEU F 1 95  ? 2.138   102.260 21.291  1.00 26.78  ? 95  LEU F O   1 
ATOM   18462 C CB  . LEU F 1 95  ? 3.171   102.789 24.463  1.00 27.42  ? 95  LEU F CB  1 
ATOM   18463 C CG  . LEU F 1 95  ? 3.595   104.107 23.791  1.00 30.79  ? 95  LEU F CG  1 
ATOM   18464 C CD1 . LEU F 1 95  ? 2.413   105.050 23.609  1.00 30.62  ? 95  LEU F CD1 1 
ATOM   18465 C CD2 . LEU F 1 95  ? 4.702   104.855 24.532  1.00 30.56  ? 95  LEU F CD2 1 
ATOM   18466 N N   . LEU F 1 96  ? 3.688   100.801 22.089  1.00 28.39  ? 96  LEU F N   1 
ATOM   18467 C CA  . LEU F 1 96  ? 4.292   100.489 20.801  1.00 26.75  ? 96  LEU F CA  1 
ATOM   18468 C C   . LEU F 1 96  ? 3.222   100.024 19.815  1.00 27.91  ? 96  LEU F C   1 
ATOM   18469 O O   . LEU F 1 96  ? 3.168   100.517 18.707  1.00 28.05  ? 96  LEU F O   1 
ATOM   18470 C CB  . LEU F 1 96  ? 5.427   99.463  20.897  1.00 24.85  ? 96  LEU F CB  1 
ATOM   18471 C CG  . LEU F 1 96  ? 6.681   99.879  21.681  1.00 22.74  ? 96  LEU F CG  1 
ATOM   18472 C CD1 . LEU F 1 96  ? 7.789   98.867  21.528  1.00 21.35  ? 96  LEU F CD1 1 
ATOM   18473 C CD2 . LEU F 1 96  ? 7.224   101.240 21.322  1.00 23.18  ? 96  LEU F CD2 1 
ATOM   18474 N N   . LEU F 1 97  ? 2.343   99.105  20.215  1.00 30.22  ? 97  LEU F N   1 
ATOM   18475 C CA  . LEU F 1 97  ? 1.311   98.612  19.314  1.00 29.98  ? 97  LEU F CA  1 
ATOM   18476 C C   . LEU F 1 97  ? 0.246   99.667  18.985  1.00 28.39  ? 97  LEU F C   1 
ATOM   18477 O O   . LEU F 1 97  ? -0.071  99.833  17.822  1.00 26.82  ? 97  LEU F O   1 
ATOM   18478 C CB  . LEU F 1 97  ? 0.699   97.358  19.923  1.00 28.25  ? 97  LEU F CB  1 
ATOM   18479 C CG  . LEU F 1 97  ? 1.553   96.098  19.791  1.00 29.62  ? 97  LEU F CG  1 
ATOM   18480 C CD1 . LEU F 1 97  ? 1.214   95.082  20.870  1.00 26.98  ? 97  LEU F CD1 1 
ATOM   18481 C CD2 . LEU F 1 97  ? 1.379   95.492  18.377  1.00 30.56  ? 97  LEU F CD2 1 
ATOM   18482 N N   . THR F 1 98  ? -0.321  100.346 19.989  1.00 28.34  ? 98  THR F N   1 
ATOM   18483 C CA  . THR F 1 98  ? -1.540  101.132 19.823  1.00 28.87  ? 98  THR F CA  1 
ATOM   18484 C C   . THR F 1 98  ? -1.242  102.599 19.515  1.00 30.34  ? 98  THR F C   1 
ATOM   18485 O O   . THR F 1 98  ? -2.106  103.291 19.002  1.00 33.56  ? 98  THR F O   1 
ATOM   18486 C CB  . THR F 1 98  ? -2.414  101.073 21.080  1.00 29.54  ? 98  THR F CB  1 
ATOM   18487 O OG1 . THR F 1 98  ? -1.716  101.600 22.215  1.00 30.93  ? 98  THR F OG1 1 
ATOM   18488 C CG2 . THR F 1 98  ? -2.925  99.676  21.367  1.00 30.08  ? 98  THR F CG2 1 
ATOM   18489 N N   . GLY F 1 99  ? -0.079  103.115 19.915  1.00 30.13  ? 99  GLY F N   1 
ATOM   18490 C CA  . GLY F 1 99  ? 0.106   104.560 19.950  1.00 31.19  ? 99  GLY F CA  1 
ATOM   18491 C C   . GLY F 1 99  ? -0.515  105.201 21.196  1.00 32.60  ? 99  GLY F C   1 
ATOM   18492 O O   . GLY F 1 99  ? -0.290  106.372 21.438  1.00 35.09  ? 99  GLY F O   1 
ATOM   18493 N N   . GLU F 1 100 ? -1.235  104.438 22.029  1.00 32.14  ? 100 GLU F N   1 
ATOM   18494 C CA  . GLU F 1 100 ? -1.925  104.992 23.190  1.00 33.69  ? 100 GLU F CA  1 
ATOM   18495 C C   . GLU F 1 100 ? -1.250  104.573 24.498  1.00 34.58  ? 100 GLU F C   1 
ATOM   18496 O O   . GLU F 1 100 ? -0.788  103.436 24.629  1.00 36.85  ? 100 GLU F O   1 
ATOM   18497 C CB  . GLU F 1 100 ? -3.381  104.521 23.138  1.00 35.04  ? 100 GLU F CB  1 
ATOM   18498 C CG  . GLU F 1 100 ? -4.114  105.122 21.945  1.00 33.51  ? 100 GLU F CG  1 
ATOM   18499 C CD  . GLU F 1 100 ? -5.407  104.450 21.576  1.00 37.37  ? 100 GLU F CD  1 
ATOM   18500 O OE1 . GLU F 1 100 ? -6.064  105.006 20.677  1.00 45.00  ? 100 GLU F OE1 1 
ATOM   18501 O OE2 . GLU F 1 100 ? -5.751  103.398 22.147  1.00 35.02  ? 100 GLU F OE2 1 
ATOM   18502 N N   . LEU F 1 101 ? -1.193  105.501 25.467  1.00 33.62  ? 101 LEU F N   1 
ATOM   18503 C CA  . LEU F 1 101 ? -0.626  105.221 26.783  1.00 34.19  ? 101 LEU F CA  1 
ATOM   18504 C C   . LEU F 1 101 ? -1.553  104.291 27.550  1.00 33.26  ? 101 LEU F C   1 
ATOM   18505 O O   . LEU F 1 101 ? -2.739  104.564 27.672  1.00 32.99  ? 101 LEU F O   1 
ATOM   18506 C CB  . LEU F 1 101 ? -0.402  106.489 27.596  1.00 33.25  ? 101 LEU F CB  1 
ATOM   18507 C CG  . LEU F 1 101 ? 0.516   107.524 26.951  1.00 36.63  ? 101 LEU F CG  1 
ATOM   18508 C CD1 . LEU F 1 101 ? 0.343   108.901 27.604  1.00 35.35  ? 101 LEU F CD1 1 
ATOM   18509 C CD2 . LEU F 1 101 ? 1.953   107.007 27.022  1.00 36.82  ? 101 LEU F CD2 1 
ATOM   18510 N N   . PRO F 1 102 ? -1.032  103.188 28.121  1.00 35.22  ? 102 PRO F N   1 
ATOM   18511 C CA  . PRO F 1 102 ? -1.879  102.233 28.836  1.00 34.22  ? 102 PRO F CA  1 
ATOM   18512 C C   . PRO F 1 102 ? -2.274  102.712 30.232  1.00 35.47  ? 102 PRO F C   1 
ATOM   18513 O O   . PRO F 1 102 ? -1.545  103.484 30.838  1.00 34.34  ? 102 PRO F O   1 
ATOM   18514 C CB  . PRO F 1 102 ? -0.952  101.031 28.907  1.00 36.16  ? 102 PRO F CB  1 
ATOM   18515 C CG  . PRO F 1 102 ? 0.433   101.646 29.074  1.00 36.43  ? 102 PRO F CG  1 
ATOM   18516 C CD  . PRO F 1 102 ? 0.402   102.841 28.146  1.00 34.58  ? 102 PRO F CD  1 
ATOM   18517 N N   . THR F 1 103 ? -3.421  102.216 30.725  1.00 38.15  ? 103 THR F N   1 
ATOM   18518 C CA  . THR F 1 103 ? -3.808  102.308 32.126  1.00 36.68  ? 103 THR F CA  1 
ATOM   18519 C C   . THR F 1 103 ? -3.109  101.223 32.942  1.00 40.84  ? 103 THR F C   1 
ATOM   18520 O O   . THR F 1 103 ? -2.547  100.260 32.422  1.00 41.72  ? 103 THR F O   1 
ATOM   18521 C CB  . THR F 1 103 ? -5.329  102.168 32.301  1.00 38.08  ? 103 THR F CB  1 
ATOM   18522 O OG1 . THR F 1 103 ? -5.814  100.863 31.957  1.00 31.24  ? 103 THR F OG1 1 
ATOM   18523 C CG2 . THR F 1 103 ? -6.092  103.233 31.525  1.00 40.98  ? 103 THR F CG2 1 
ATOM   18524 N N   . GLU F 1 104 ? -3.249  101.363 34.258  1.00 46.57  ? 104 GLU F N   1 
ATOM   18525 C CA  . GLU F 1 104 ? -2.911  100.316 35.206  1.00 48.36  ? 104 GLU F CA  1 
ATOM   18526 C C   . GLU F 1 104 ? -3.514  98.997  34.726  1.00 42.95  ? 104 GLU F C   1 
ATOM   18527 O O   . GLU F 1 104 ? -2.802  98.011  34.578  1.00 44.31  ? 104 GLU F O   1 
ATOM   18528 C CB  . GLU F 1 104 ? -3.365  100.735 36.611  1.00 48.12  ? 104 GLU F CB  1 
ATOM   18529 C CG  . GLU F 1 104 ? -2.611  101.947 37.166  1.00 48.67  ? 104 GLU F CG  1 
ATOM   18530 C CD  . GLU F 1 104 ? -1.141  101.712 37.494  1.00 53.27  ? 104 GLU F CD  1 
ATOM   18531 O OE1 . GLU F 1 104 ? -0.393  102.722 37.593  1.00 43.55  ? 104 GLU F OE1 1 
ATOM   18532 O OE2 . GLU F 1 104 ? -0.747  100.520 37.658  1.00 59.43  ? 104 GLU F OE2 1 
ATOM   18533 N N   . GLU F 1 105 ? -4.815  99.011  34.444  1.00 40.90  ? 105 GLU F N   1 
ATOM   18534 C CA  . GLU F 1 105 ? -5.532  97.787  34.170  1.00 47.97  ? 105 GLU F CA  1 
ATOM   18535 C C   . GLU F 1 105 ? -5.000  97.161  32.875  1.00 46.89  ? 105 GLU F C   1 
ATOM   18536 O O   . GLU F 1 105 ? -4.849  95.943  32.817  1.00 41.22  ? 105 GLU F O   1 
ATOM   18537 C CB  . GLU F 1 105 ? -7.044  98.039  34.143  1.00 56.46  ? 105 GLU F CB  1 
ATOM   18538 C CG  . GLU F 1 105 ? -7.850  97.231  35.170  1.00 63.25  ? 105 GLU F CG  1 
ATOM   18539 C CD  . GLU F 1 105 ? -7.617  95.726  35.335  1.00 65.27  ? 105 GLU F CD  1 
ATOM   18540 O OE1 . GLU F 1 105 ? -7.291  95.350  36.477  1.00 58.48  ? 105 GLU F OE1 1 
ATOM   18541 O OE2 . GLU F 1 105 ? -7.772  94.919  34.384  1.00 67.85  ? 105 GLU F OE2 1 
ATOM   18542 N N   . ASP F 1 106 ? -4.716  97.977  31.844  1.00 41.71  ? 106 ASP F N   1 
ATOM   18543 C CA  . ASP F 1 106 ? -4.238  97.454  30.572  1.00 43.17  ? 106 ASP F CA  1 
ATOM   18544 C C   . ASP F 1 106 ? -2.897  96.725  30.713  1.00 41.17  ? 106 ASP F C   1 
ATOM   18545 O O   . ASP F 1 106 ? -2.640  95.780  29.960  1.00 37.59  ? 106 ASP F O   1 
ATOM   18546 C CB  . ASP F 1 106 ? -3.978  98.565  29.569  1.00 45.61  ? 106 ASP F CB  1 
ATOM   18547 C CG  . ASP F 1 106 ? -5.177  99.419  29.213  1.00 45.54  ? 106 ASP F CG  1 
ATOM   18548 O OD1 . ASP F 1 106 ? -6.311  98.925  29.397  1.00 51.20  ? 106 ASP F OD1 1 
ATOM   18549 O OD2 . ASP F 1 106 ? -4.944  100.580 28.809  1.00 41.61  ? 106 ASP F OD2 1 
ATOM   18550 N N   . VAL F 1 107 ? -2.025  97.220  31.619  1.00 37.18  ? 107 VAL F N   1 
ATOM   18551 C CA  . VAL F 1 107 ? -0.719  96.618  31.858  1.00 38.03  ? 107 VAL F CA  1 
ATOM   18552 C C   . VAL F 1 107 ? -0.877  95.279  32.592  1.00 38.30  ? 107 VAL F C   1 
ATOM   18553 O O   . VAL F 1 107 ? -0.208  94.302  32.250  1.00 37.48  ? 107 VAL F O   1 
ATOM   18554 C CB  . VAL F 1 107 ? 0.248   97.542  32.608  1.00 35.02  ? 107 VAL F CB  1 
ATOM   18555 C CG1 . VAL F 1 107 ? 1.579   96.864  32.844  1.00 36.84  ? 107 VAL F CG1 1 
ATOM   18556 C CG2 . VAL F 1 107 ? 0.492   98.853  31.880  1.00 37.21  ? 107 VAL F CG2 1 
ATOM   18557 N N   . LYS F 1 108 ? -1.805  95.219  33.550  1.00 38.58  ? 108 LYS F N   1 
ATOM   18558 C CA  . LYS F 1 108 ? -2.076  93.985  34.269  1.00 46.41  ? 108 LYS F CA  1 
ATOM   18559 C C   . LYS F 1 108 ? -2.710  92.940  33.353  1.00 39.59  ? 108 LYS F C   1 
ATOM   18560 O O   . LYS F 1 108 ? -2.568  91.747  33.603  1.00 39.82  ? 108 LYS F O   1 
ATOM   18561 C CB  . LYS F 1 108 ? -2.907  94.232  35.533  1.00 53.59  ? 108 LYS F CB  1 
ATOM   18562 C CG  . LYS F 1 108 ? -2.102  94.921  36.626  1.00 62.63  ? 108 LYS F CG  1 
ATOM   18563 C CD  . LYS F 1 108 ? -2.958  95.373  37.799  1.00 66.46  ? 108 LYS F CD  1 
ATOM   18564 C CE  . LYS F 1 108 ? -2.193  96.190  38.785  1.00 67.30  ? 108 LYS F CE  1 
ATOM   18565 N NZ  . LYS F 1 108 ? -3.152  96.954  39.586  1.00 70.39  ? 108 LYS F NZ  1 
ATOM   18566 N N   . GLU F 1 109 ? -3.391  93.374  32.295  1.00 38.17  ? 109 GLU F N   1 
ATOM   18567 C CA  . GLU F 1 109 ? -3.945  92.437  31.328  1.00 39.77  ? 109 GLU F CA  1 
ATOM   18568 C C   . GLU F 1 109 ? -2.805  91.727  30.587  1.00 38.15  ? 109 GLU F C   1 
ATOM   18569 O O   . GLU F 1 109 ? -2.862  90.513  30.376  1.00 36.17  ? 109 GLU F O   1 
ATOM   18570 C CB  . GLU F 1 109 ? -4.912  93.111  30.353  1.00 45.83  ? 109 GLU F CB  1 
ATOM   18571 C CG  . GLU F 1 109 ? -6.348  93.289  30.855  1.00 51.69  ? 109 GLU F CG  1 
ATOM   18572 C CD  . GLU F 1 109 ? -7.365  93.738  29.800  1.00 54.78  ? 109 GLU F CD  1 
ATOM   18573 O OE1 . GLU F 1 109 ? -8.518  93.995  30.195  1.00 68.14  ? 109 GLU F OE1 1 
ATOM   18574 O OE2 . GLU F 1 109 ? -7.058  93.838  28.591  1.00 54.05  ? 109 GLU F OE2 1 
ATOM   18575 N N   . ILE F 1 110 ? -1.751  92.481  30.236  1.00 35.39  ? 110 ILE F N   1 
ATOM   18576 C CA  . ILE F 1 110 ? -0.616  91.955  29.488  1.00 34.27  ? 110 ILE F CA  1 
ATOM   18577 C C   . ILE F 1 110 ? 0.265   91.084  30.382  1.00 32.26  ? 110 ILE F C   1 
ATOM   18578 O O   . ILE F 1 110 ? 0.670   89.998  29.967  1.00 28.85  ? 110 ILE F O   1 
ATOM   18579 C CB  . ILE F 1 110 ? 0.180   93.117  28.889  1.00 37.55  ? 110 ILE F CB  1 
ATOM   18580 C CG1 . ILE F 1 110 ? -0.695  93.889  27.913  1.00 35.89  ? 110 ILE F CG1 1 
ATOM   18581 C CG2 . ILE F 1 110 ? 1.475   92.619  28.242  1.00 39.70  ? 110 ILE F CG2 1 
ATOM   18582 C CD1 . ILE F 1 110 ? -0.107  95.207  27.483  1.00 36.83  ? 110 ILE F CD1 1 
ATOM   18583 N N   . SER F 1 111 ? 0.550   91.575  31.599  1.00 28.31  ? 111 SER F N   1 
ATOM   18584 C CA  . SER F 1 111 ? 1.357   90.834  32.559  1.00 29.80  ? 111 SER F CA  1 
ATOM   18585 C C   . SER F 1 111 ? 0.774   89.440  32.794  1.00 31.37  ? 111 SER F C   1 
ATOM   18586 O O   . SER F 1 111 ? 1.529   88.457  32.876  1.00 30.83  ? 111 SER F O   1 
ATOM   18587 C CB  . SER F 1 111 ? 1.517   91.586  33.862  1.00 29.89  ? 111 SER F CB  1 
ATOM   18588 O OG  . SER F 1 111 ? 2.290   92.777  33.706  1.00 32.03  ? 111 SER F OG  1 
ATOM   18589 N N   . ALA F 1 112 ? -0.565  89.378  32.879  1.00 27.90  ? 112 ALA F N   1 
ATOM   18590 C CA  . ALA F 1 112 ? -1.286  88.160  33.197  1.00 30.35  ? 112 ALA F CA  1 
ATOM   18591 C C   . ALA F 1 112 ? -1.230  87.199  32.016  1.00 33.27  ? 112 ALA F C   1 
ATOM   18592 O O   . ALA F 1 112 ? -1.156  85.977  32.187  1.00 30.54  ? 112 ALA F O   1 
ATOM   18593 C CB  . ALA F 1 112 ? -2.727  88.500  33.542  1.00 31.30  ? 112 ALA F CB  1 
ATOM   18594 N N   . GLU F 1 113 ? -1.291  87.789  30.814  1.00 35.71  ? 113 GLU F N   1 
ATOM   18595 C CA  . GLU F 1 113 ? -1.217  87.031  29.577  1.00 36.77  ? 113 GLU F CA  1 
ATOM   18596 C C   . GLU F 1 113 ? 0.178   86.397  29.433  1.00 38.13  ? 113 GLU F C   1 
ATOM   18597 O O   . GLU F 1 113 ? 0.289   85.217  29.063  1.00 36.27  ? 113 GLU F O   1 
ATOM   18598 C CB  . GLU F 1 113 ? -1.699  87.971  28.471  1.00 38.38  ? 113 GLU F CB  1 
ATOM   18599 C CG  . GLU F 1 113 ? -2.261  87.235  27.262  1.00 40.84  ? 113 GLU F CG  1 
ATOM   18600 C CD  . GLU F 1 113 ? -3.638  86.639  27.432  1.00 43.84  ? 113 GLU F CD  1 
ATOM   18601 O OE1 . GLU F 1 113 ? -3.806  85.395  27.377  1.00 46.36  ? 113 GLU F OE1 1 
ATOM   18602 O OE2 . GLU F 1 113 ? -4.546  87.469  27.603  1.00 43.77  ? 113 GLU F OE2 1 
ATOM   18603 N N   . PHE F 1 114 ? 1.237   87.163  29.770  1.00 34.92  ? 114 PHE F N   1 
ATOM   18604 C CA  . PHE F 1 114 ? 2.601   86.647  29.797  1.00 32.96  ? 114 PHE F CA  1 
ATOM   18605 C C   . PHE F 1 114 ? 2.718   85.543  30.846  1.00 33.07  ? 114 PHE F C   1 
ATOM   18606 O O   . PHE F 1 114 ? 3.283   84.489  30.585  1.00 33.76  ? 114 PHE F O   1 
ATOM   18607 C CB  . PHE F 1 114 ? 3.611   87.780  30.020  1.00 30.91  ? 114 PHE F CB  1 
ATOM   18608 C CG  . PHE F 1 114 ? 3.766   88.773  28.873  1.00 31.97  ? 114 PHE F CG  1 
ATOM   18609 C CD1 . PHE F 1 114 ? 3.208   88.547  27.621  1.00 33.76  ? 114 PHE F CD1 1 
ATOM   18610 C CD2 . PHE F 1 114 ? 4.534   89.912  29.028  1.00 33.73  ? 114 PHE F CD2 1 
ATOM   18611 C CE1 . PHE F 1 114 ? 3.391   89.448  26.588  1.00 36.99  ? 114 PHE F CE1 1 
ATOM   18612 C CE2 . PHE F 1 114 ? 4.730   90.805  27.986  1.00 33.28  ? 114 PHE F CE2 1 
ATOM   18613 C CZ  . PHE F 1 114 ? 4.153   90.573  26.770  1.00 37.36  ? 114 PHE F CZ  1 
ATOM   18614 N N   . THR F 1 115 ? 2.141   85.765  32.024  1.00 35.49  ? 115 THR F N   1 
ATOM   18615 C CA  . THR F 1 115 ? 2.257   84.807  33.117  1.00 40.20  ? 115 THR F CA  1 
ATOM   18616 C C   . THR F 1 115 ? 1.615   83.469  32.734  1.00 38.18  ? 115 THR F C   1 
ATOM   18617 O O   . THR F 1 115 ? 2.210   82.411  32.932  1.00 40.29  ? 115 THR F O   1 
ATOM   18618 C CB  . THR F 1 115 ? 1.618   85.419  34.371  1.00 39.99  ? 115 THR F CB  1 
ATOM   18619 O OG1 . THR F 1 115 ? 2.578   86.370  34.835  1.00 34.38  ? 115 THR F OG1 1 
ATOM   18620 C CG2 . THR F 1 115 ? 1.245   84.365  35.405  1.00 39.96  ? 115 THR F CG2 1 
ATOM   18621 N N   . LYS F 1 116 ? 0.387   83.532  32.217  1.00 32.89  ? 116 LYS F N   1 
ATOM   18622 C CA  . LYS F 1 116 ? -0.360  82.338  31.889  1.00 37.93  ? 116 LYS F CA  1 
ATOM   18623 C C   . LYS F 1 116 ? 0.428   81.491  30.882  1.00 38.42  ? 116 LYS F C   1 
ATOM   18624 O O   . LYS F 1 116 ? 0.601   80.288  31.098  1.00 35.90  ? 116 LYS F O   1 
ATOM   18625 C CB  . LYS F 1 116 ? -1.753  82.786  31.430  1.00 49.42  ? 116 LYS F CB  1 
ATOM   18626 C CG  . LYS F 1 116 ? -2.577  81.718  30.689  1.00 62.09  ? 116 LYS F CG  1 
ATOM   18627 C CD  . LYS F 1 116 ? -3.915  82.191  30.114  1.00 71.42  ? 116 LYS F CD  1 
ATOM   18628 C CE  . LYS F 1 116 ? -4.834  81.023  29.845  1.00 80.97  ? 116 LYS F CE  1 
ATOM   18629 N NZ  . LYS F 1 116 ? -6.182  81.414  29.415  1.00 84.14  ? 116 LYS F NZ  1 
ATOM   18630 N N   . ARG F 1 117 ? 0.935   82.123  29.802  1.00 33.00  ? 117 ARG F N   1 
ATOM   18631 C CA  . ARG F 1 117 ? 1.541   81.397  28.689  1.00 31.61  ? 117 ARG F CA  1 
ATOM   18632 C C   . ARG F 1 117 ? 2.996   81.007  28.979  1.00 31.24  ? 117 ARG F C   1 
ATOM   18633 O O   . ARG F 1 117 ? 3.577   80.220  28.259  1.00 28.15  ? 117 ARG F O   1 
ATOM   18634 C CB  . ARG F 1 117 ? 1.473   82.228  27.408  1.00 30.70  ? 117 ARG F CB  1 
ATOM   18635 C CG  . ARG F 1 117 ? 0.062   82.592  26.984  1.00 32.00  ? 117 ARG F CG  1 
ATOM   18636 C CD  . ARG F 1 117 ? 0.101   83.732  26.015  1.00 30.81  ? 117 ARG F CD  1 
ATOM   18637 N NE  . ARG F 1 117 ? -1.241  84.262  25.765  1.00 35.01  ? 117 ARG F NE  1 
ATOM   18638 C CZ  . ARG F 1 117 ? -1.978  84.001  24.694  1.00 38.46  ? 117 ARG F CZ  1 
ATOM   18639 N NH1 . ARG F 1 117 ? -1.689  82.963  23.916  1.00 41.89  ? 117 ARG F NH1 1 
ATOM   18640 N NH2 . ARG F 1 117 ? -3.019  84.768  24.430  1.00 35.80  ? 117 ARG F NH2 1 
ATOM   18641 N N   . MET F 1 118 ? 3.569   81.542  30.053  1.00 33.58  ? 118 MET F N   1 
ATOM   18642 C CA  . MET F 1 118 ? 4.869   81.136  30.562  1.00 34.16  ? 118 MET F CA  1 
ATOM   18643 C C   . MET F 1 118 ? 4.919   79.632  30.859  1.00 30.59  ? 118 MET F C   1 
ATOM   18644 O O   . MET F 1 118 ? 5.989   79.023  30.876  1.00 27.89  ? 118 MET F O   1 
ATOM   18645 C CB  . MET F 1 118 ? 5.160   81.934  31.839  1.00 38.46  ? 118 MET F CB  1 
ATOM   18646 C CG  . MET F 1 118 ? 6.620   82.204  32.050  1.00 42.62  ? 118 MET F CG  1 
ATOM   18647 S SD  . MET F 1 118 ? 6.926   83.586  33.157  1.00 45.12  ? 118 MET F SD  1 
ATOM   18648 C CE  . MET F 1 118 ? 6.804   84.944  31.986  1.00 50.80  ? 118 MET F CE  1 
ATOM   18649 N N   . GLN F 1 119 ? 3.755   79.017  31.081  1.00 29.81  ? 119 GLN F N   1 
ATOM   18650 C CA  . GLN F 1 119 ? 3.696   77.622  31.482  1.00 31.59  ? 119 GLN F CA  1 
ATOM   18651 C C   . GLN F 1 119 ? 3.695   76.723  30.246  1.00 31.83  ? 119 GLN F C   1 
ATOM   18652 O O   . GLN F 1 119 ? 3.752   75.498  30.374  1.00 35.15  ? 119 GLN F O   1 
ATOM   18653 C CB  . GLN F 1 119 ? 2.425   77.322  32.284  1.00 36.61  ? 119 GLN F CB  1 
ATOM   18654 C CG  . GLN F 1 119 ? 2.211   78.156  33.549  1.00 44.04  ? 119 GLN F CG  1 
ATOM   18655 C CD  . GLN F 1 119 ? 3.229   77.881  34.636  1.00 47.13  ? 119 GLN F CD  1 
ATOM   18656 O OE1 . GLN F 1 119 ? 3.482   76.728  35.000  1.00 45.79  ? 119 GLN F OE1 1 
ATOM   18657 N NE2 . GLN F 1 119 ? 3.839   78.940  35.150  1.00 44.82  ? 119 GLN F NE2 1 
ATOM   18658 N N   . ASN F 1 120 ? 3.582   77.311  29.049  1.00 28.40  ? 120 ASN F N   1 
ATOM   18659 C CA  . ASN F 1 120 ? 3.309   76.497  27.882  1.00 31.70  ? 120 ASN F CA  1 
ATOM   18660 C C   . ASN F 1 120 ? 4.528   76.342  26.974  1.00 31.67  ? 120 ASN F C   1 
ATOM   18661 O O   . ASN F 1 120 ? 4.346   76.106  25.784  1.00 31.08  ? 120 ASN F O   1 
ATOM   18662 C CB  . ASN F 1 120 ? 2.134   77.053  27.094  1.00 34.54  ? 120 ASN F CB  1 
ATOM   18663 C CG  . ASN F 1 120 ? 0.887   77.134  27.936  1.00 35.46  ? 120 ASN F CG  1 
ATOM   18664 O OD1 . ASN F 1 120 ? 0.672   76.318  28.849  1.00 41.54  ? 120 ASN F OD1 1 
ATOM   18665 N ND2 . ASN F 1 120 ? 0.044   78.093  27.604  1.00 32.74  ? 120 ASN F ND2 1 
ATOM   18666 N N   . VAL F 1 121 ? 5.754   76.396  27.527  1.00 28.53  ? 121 VAL F N   1 
ATOM   18667 C CA  . VAL F 1 121 ? 6.922   76.142  26.708  1.00 26.15  ? 121 VAL F CA  1 
ATOM   18668 C C   . VAL F 1 121 ? 7.049   74.636  26.582  1.00 23.43  ? 121 VAL F C   1 
ATOM   18669 O O   . VAL F 1 121 ? 7.147   73.958  27.588  1.00 24.26  ? 121 VAL F O   1 
ATOM   18670 C CB  . VAL F 1 121 ? 8.218   76.751  27.251  1.00 26.52  ? 121 VAL F CB  1 
ATOM   18671 C CG1 . VAL F 1 121 ? 9.382   76.511  26.295  1.00 28.55  ? 121 VAL F CG1 1 
ATOM   18672 C CG2 . VAL F 1 121 ? 8.059   78.238  27.520  1.00 27.41  ? 121 VAL F CG2 1 
ATOM   18673 N N   . PRO F 1 122 ? 7.049   74.072  25.360  1.00 21.59  ? 122 PRO F N   1 
ATOM   18674 C CA  . PRO F 1 122 ? 7.075   72.619  25.167  1.00 21.94  ? 122 PRO F CA  1 
ATOM   18675 C C   . PRO F 1 122 ? 8.307   71.967  25.773  1.00 24.23  ? 122 PRO F C   1 
ATOM   18676 O O   . PRO F 1 122 ? 9.364   72.573  25.857  1.00 28.15  ? 122 PRO F O   1 
ATOM   18677 C CB  . PRO F 1 122 ? 7.044   72.426  23.643  1.00 22.79  ? 122 PRO F CB  1 
ATOM   18678 C CG  . PRO F 1 122 ? 6.596   73.759  23.071  1.00 22.30  ? 122 PRO F CG  1 
ATOM   18679 C CD  . PRO F 1 122 ? 7.059   74.806  24.092  1.00 22.32  ? 122 PRO F CD  1 
ATOM   18680 N N   . GLN F 1 123 ? 8.176   70.707  26.172  1.00 28.18  ? 123 GLN F N   1 
ATOM   18681 C CA  . GLN F 1 123 ? 9.289   69.958  26.738  1.00 30.06  ? 123 GLN F CA  1 
ATOM   18682 C C   . GLN F 1 123 ? 10.414  69.860  25.715  1.00 27.14  ? 123 GLN F C   1 
ATOM   18683 O O   . GLN F 1 123 ? 11.553  70.013  26.107  1.00 28.77  ? 123 GLN F O   1 
ATOM   18684 C CB  . GLN F 1 123 ? 8.780   68.593  27.216  1.00 38.54  ? 123 GLN F CB  1 
ATOM   18685 C CG  . GLN F 1 123 ? 9.808   67.640  27.824  1.00 45.27  ? 123 GLN F CG  1 
ATOM   18686 C CD  . GLN F 1 123 ? 10.605  68.262  28.948  1.00 58.92  ? 123 GLN F CD  1 
ATOM   18687 O OE1 . GLN F 1 123 ? 10.036  68.809  29.902  1.00 65.62  ? 123 GLN F OE1 1 
ATOM   18688 N NE2 . GLN F 1 123 ? 11.931  68.196  28.844  1.00 62.57  ? 123 GLN F NE2 1 
ATOM   18689 N N   . TYR F 1 124 ? 10.098  69.650  24.419  1.00 26.56  ? 124 TYR F N   1 
ATOM   18690 C CA  . TYR F 1 124 ? 11.103  69.466  23.370  1.00 24.16  ? 124 TYR F CA  1 
ATOM   18691 C C   . TYR F 1 124 ? 12.034  70.686  23.223  1.00 21.36  ? 124 TYR F C   1 
ATOM   18692 O O   . TYR F 1 124 ? 13.184  70.552  22.864  1.00 21.79  ? 124 TYR F O   1 
ATOM   18693 C CB  . TYR F 1 124 ? 10.487  69.059  22.023  1.00 24.08  ? 124 TYR F CB  1 
ATOM   18694 C CG  . TYR F 1 124 ? 9.656   70.130  21.324  1.00 24.97  ? 124 TYR F CG  1 
ATOM   18695 C CD1 . TYR F 1 124 ? 10.228  71.189  20.637  1.00 24.30  ? 124 TYR F CD1 1 
ATOM   18696 C CD2 . TYR F 1 124 ? 8.277   70.068  21.359  1.00 26.65  ? 124 TYR F CD2 1 
ATOM   18697 C CE1 . TYR F 1 124 ? 9.451   72.160  20.025  1.00 23.97  ? 124 TYR F CE1 1 
ATOM   18698 C CE2 . TYR F 1 124 ? 7.490   71.029  20.758  1.00 25.67  ? 124 TYR F CE2 1 
ATOM   18699 C CZ  . TYR F 1 124 ? 8.074   72.076  20.080  1.00 24.52  ? 124 TYR F CZ  1 
ATOM   18700 O OH  . TYR F 1 124 ? 7.206   72.969  19.517  1.00 22.73  ? 124 TYR F OH  1 
ATOM   18701 N N   . VAL F 1 125 ? 11.619  71.894  23.556  1.00 22.77  ? 125 VAL F N   1 
ATOM   18702 C CA  . VAL F 1 125 ? 12.539  73.022  23.480  1.00 22.00  ? 125 VAL F CA  1 
ATOM   18703 C C   . VAL F 1 125 ? 13.695  72.792  24.454  1.00 24.17  ? 125 VAL F C   1 
ATOM   18704 O O   . VAL F 1 125 ? 14.850  73.026  24.126  1.00 23.99  ? 125 VAL F O   1 
ATOM   18705 C CB  . VAL F 1 125 ? 11.785  74.326  23.787  1.00 20.98  ? 125 VAL F CB  1 
ATOM   18706 C CG1 . VAL F 1 125 ? 12.724  75.502  24.006  1.00 21.96  ? 125 VAL F CG1 1 
ATOM   18707 C CG2 . VAL F 1 125 ? 10.765  74.651  22.702  1.00 20.43  ? 125 VAL F CG2 1 
ATOM   18708 N N   . PHE F 1 126 ? 13.381  72.309  25.660  1.00 24.22  ? 126 PHE F N   1 
ATOM   18709 C CA  . PHE F 1 126 ? 14.384  72.036  26.680  1.00 24.09  ? 126 PHE F CA  1 
ATOM   18710 C C   . PHE F 1 126 ? 15.264  70.872  26.234  1.00 22.07  ? 126 PHE F C   1 
ATOM   18711 O O   . PHE F 1 126 ? 16.473  70.867  26.476  1.00 24.42  ? 126 PHE F O   1 
ATOM   18712 C CB  . PHE F 1 126 ? 13.721  71.766  28.042  1.00 24.45  ? 126 PHE F CB  1 
ATOM   18713 C CG  . PHE F 1 126 ? 12.898  72.935  28.556  1.00 26.36  ? 126 PHE F CG  1 
ATOM   18714 C CD1 . PHE F 1 126 ? 13.497  74.153  28.864  1.00 30.35  ? 126 PHE F CD1 1 
ATOM   18715 C CD2 . PHE F 1 126 ? 11.531  72.824  28.739  1.00 28.50  ? 126 PHE F CD2 1 
ATOM   18716 C CE1 . PHE F 1 126 ? 12.754  75.237  29.350  1.00 29.98  ? 126 PHE F CE1 1 
ATOM   18717 C CE2 . PHE F 1 126 ? 10.793  73.909  29.201  1.00 34.29  ? 126 PHE F CE2 1 
ATOM   18718 C CZ  . PHE F 1 126 ? 11.405  75.124  29.486  1.00 31.81  ? 126 PHE F CZ  1 
ATOM   18719 N N   . ASP F 1 127 ? 14.669  69.880  25.583  1.00 21.55  ? 127 ASP F N   1 
ATOM   18720 C CA  . ASP F 1 127 ? 15.456  68.827  24.949  1.00 24.12  ? 127 ASP F CA  1 
ATOM   18721 C C   . ASP F 1 127 ? 16.422  69.402  23.901  1.00 24.43  ? 127 ASP F C   1 
ATOM   18722 O O   . ASP F 1 127 ? 17.558  68.942  23.795  1.00 24.30  ? 127 ASP F O   1 
ATOM   18723 C CB  . ASP F 1 127 ? 14.584  67.757  24.303  1.00 24.25  ? 127 ASP F CB  1 
ATOM   18724 C CG  . ASP F 1 127 ? 13.644  66.974  25.214  1.00 24.56  ? 127 ASP F CG  1 
ATOM   18725 O OD1 . ASP F 1 127 ? 13.829  67.042  26.451  1.00 26.68  ? 127 ASP F OD1 1 
ATOM   18726 O OD2 . ASP F 1 127 ? 12.759  66.280  24.673  1.00 24.32  ? 127 ASP F OD2 1 
ATOM   18727 N N   . VAL F 1 128 ? 15.969  70.352  23.071  1.00 23.41  ? 128 VAL F N   1 
ATOM   18728 C CA  . VAL F 1 128 ? 16.857  70.919  22.073  1.00 23.21  ? 128 VAL F CA  1 
ATOM   18729 C C   . VAL F 1 128 ? 18.022  71.634  22.764  1.00 24.81  ? 128 VAL F C   1 
ATOM   18730 O O   . VAL F 1 128 ? 19.192  71.460  22.390  1.00 26.69  ? 128 VAL F O   1 
ATOM   18731 C CB  . VAL F 1 128 ? 16.100  71.879  21.148  1.00 23.75  ? 128 VAL F CB  1 
ATOM   18732 C CG1 . VAL F 1 128 ? 17.064  72.776  20.378  1.00 25.67  ? 128 VAL F CG1 1 
ATOM   18733 C CG2 . VAL F 1 128 ? 15.193  71.131  20.193  1.00 22.91  ? 128 VAL F CG2 1 
ATOM   18734 N N   . LEU F 1 129 ? 17.695  72.466  23.761  1.00 23.30  ? 129 LEU F N   1 
ATOM   18735 C CA  . LEU F 1 129 ? 18.692  73.227  24.494  1.00 23.64  ? 129 LEU F CA  1 
ATOM   18736 C C   . LEU F 1 129 ? 19.758  72.322  25.100  1.00 23.91  ? 129 LEU F C   1 
ATOM   18737 O O   . LEU F 1 129 ? 20.938  72.667  25.081  1.00 23.87  ? 129 LEU F O   1 
ATOM   18738 C CB  . LEU F 1 129 ? 17.979  74.058  25.549  1.00 24.90  ? 129 LEU F CB  1 
ATOM   18739 C CG  . LEU F 1 129 ? 17.221  75.254  24.972  1.00 26.75  ? 129 LEU F CG  1 
ATOM   18740 C CD1 . LEU F 1 129 ? 16.310  75.793  26.030  1.00 28.38  ? 129 LEU F CD1 1 
ATOM   18741 C CD2 . LEU F 1 129 ? 18.121  76.379  24.442  1.00 26.31  ? 129 LEU F CD2 1 
ATOM   18742 N N   . ARG F 1 130 ? 19.339  71.175  25.644  1.00 23.38  ? 130 ARG F N   1 
ATOM   18743 C CA  . ARG F 1 130 ? 20.247  70.304  26.364  1.00 23.10  ? 130 ARG F CA  1 
ATOM   18744 C C   . ARG F 1 130 ? 21.093  69.524  25.368  1.00 23.51  ? 130 ARG F C   1 
ATOM   18745 O O   . ARG F 1 130 ? 22.220  69.131  25.665  1.00 23.75  ? 130 ARG F O   1 
ATOM   18746 C CB  . ARG F 1 130 ? 19.501  69.307  27.258  1.00 26.21  ? 130 ARG F CB  1 
ATOM   18747 C CG  . ARG F 1 130 ? 18.887  69.848  28.537  1.00 29.48  ? 130 ARG F CG  1 
ATOM   18748 C CD  . ARG F 1 130 ? 18.440  68.754  29.518  1.00 29.49  ? 130 ARG F CD  1 
ATOM   18749 N NE  . ARG F 1 130 ? 19.469  68.178  30.389  1.00 28.96  ? 130 ARG F NE  1 
ATOM   18750 C CZ  . ARG F 1 130 ? 20.178  68.815  31.332  1.00 30.70  ? 130 ARG F CZ  1 
ATOM   18751 N NH1 . ARG F 1 130 ? 21.144  68.152  31.960  1.00 30.51  ? 130 ARG F NH1 1 
ATOM   18752 N NH2 . ARG F 1 130 ? 19.951  70.097  31.632  1.00 28.56  ? 130 ARG F NH2 1 
ATOM   18753 N N   . ALA F 1 131 ? 20.534  69.285  24.179  1.00 25.44  ? 131 ALA F N   1 
ATOM   18754 C CA  . ALA F 1 131 ? 21.265  68.607  23.121  1.00 25.13  ? 131 ALA F CA  1 
ATOM   18755 C C   . ALA F 1 131 ? 22.477  69.433  22.686  1.00 25.48  ? 131 ALA F C   1 
ATOM   18756 O O   . ALA F 1 131 ? 23.476  68.871  22.222  1.00 24.41  ? 131 ALA F O   1 
ATOM   18757 C CB  . ALA F 1 131 ? 20.343  68.311  21.978  1.00 24.29  ? 131 ALA F CB  1 
ATOM   18758 N N   . MET F 1 132 ? 22.401  70.758  22.887  1.00 24.78  ? 132 MET F N   1 
ATOM   18759 C CA  . MET F 1 132 ? 23.522  71.634  22.582  1.00 24.92  ? 132 MET F CA  1 
ATOM   18760 C C   . MET F 1 132 ? 24.624  71.493  23.634  1.00 25.85  ? 132 MET F C   1 
ATOM   18761 O O   . MET F 1 132 ? 24.356  71.399  24.821  1.00 26.33  ? 132 MET F O   1 
ATOM   18762 C CB  . MET F 1 132 ? 23.055  73.083  22.504  1.00 24.85  ? 132 MET F CB  1 
ATOM   18763 C CG  . MET F 1 132 ? 22.184  73.339  21.296  1.00 26.53  ? 132 MET F CG  1 
ATOM   18764 S SD  . MET F 1 132 ? 21.371  74.943  21.368  1.00 28.91  ? 132 MET F SD  1 
ATOM   18765 C CE  . MET F 1 132 ? 22.329  75.751  20.086  1.00 28.80  ? 132 MET F CE  1 
ATOM   18766 N N   . PRO F 1 133 ? 25.916  71.435  23.258  1.00 25.48  ? 133 PRO F N   1 
ATOM   18767 C CA  . PRO F 1 133 ? 26.981  71.379  24.261  1.00 23.89  ? 133 PRO F CA  1 
ATOM   18768 C C   . PRO F 1 133 ? 26.937  72.623  25.136  1.00 24.11  ? 133 PRO F C   1 
ATOM   18769 O O   . PRO F 1 133 ? 26.725  73.722  24.641  1.00 22.57  ? 133 PRO F O   1 
ATOM   18770 C CB  . PRO F 1 133 ? 28.259  71.301  23.433  1.00 23.67  ? 133 PRO F CB  1 
ATOM   18771 C CG  . PRO F 1 133 ? 27.787  70.793  22.086  1.00 24.78  ? 133 PRO F CG  1 
ATOM   18772 C CD  . PRO F 1 133 ? 26.421  71.430  21.885  1.00 24.56  ? 133 PRO F CD  1 
ATOM   18773 N N   . VAL F 1 134 ? 27.190  72.435  26.435  1.00 26.99  ? 134 VAL F N   1 
ATOM   18774 C CA  . VAL F 1 134 ? 26.946  73.480  27.401  1.00 25.53  ? 134 VAL F CA  1 
ATOM   18775 C C   . VAL F 1 134 ? 27.846  74.680  27.150  1.00 24.46  ? 134 VAL F C   1 
ATOM   18776 O O   . VAL F 1 134 ? 27.520  75.763  27.614  1.00 26.31  ? 134 VAL F O   1 
ATOM   18777 C CB  . VAL F 1 134 ? 27.099  72.993  28.848  1.00 29.28  ? 134 VAL F CB  1 
ATOM   18778 C CG1 . VAL F 1 134 ? 28.559  72.725  29.206  1.00 30.01  ? 134 VAL F CG1 1 
ATOM   18779 C CG2 . VAL F 1 134 ? 26.512  74.009  29.822  1.00 28.21  ? 134 VAL F CG2 1 
ATOM   18780 N N   . ASP F 1 135 ? 28.966  74.519  26.439  1.00 27.33  ? 135 ASP F N   1 
ATOM   18781 C CA  . ASP F 1 135 ? 29.866  75.657  26.195  1.00 28.87  ? 135 ASP F CA  1 
ATOM   18782 C C   . ASP F 1 135 ? 29.469  76.441  24.938  1.00 25.53  ? 135 ASP F C   1 
ATOM   18783 O O   . ASP F 1 135 ? 30.217  77.300  24.495  1.00 26.04  ? 135 ASP F O   1 
ATOM   18784 C CB  . ASP F 1 135 ? 31.323  75.236  26.083  1.00 26.15  ? 135 ASP F CB  1 
ATOM   18785 C CG  . ASP F 1 135 ? 31.571  74.197  25.008  1.00 28.07  ? 135 ASP F CG  1 
ATOM   18786 O OD1 . ASP F 1 135 ? 30.590  73.898  24.289  1.00 29.48  ? 135 ASP F OD1 1 
ATOM   18787 O OD2 . ASP F 1 135 ? 32.720  73.697  24.898  1.00 25.85  ? 135 ASP F OD2 1 
ATOM   18788 N N   . THR F 1 136 ? 28.311  76.127  24.355  1.00 23.22  ? 136 THR F N   1 
ATOM   18789 C CA  . THR F 1 136 ? 27.773  76.901  23.259  1.00 24.00  ? 136 THR F CA  1 
ATOM   18790 C C   . THR F 1 136 ? 27.440  78.305  23.770  1.00 25.75  ? 136 THR F C   1 
ATOM   18791 O O   . THR F 1 136 ? 26.925  78.493  24.879  1.00 25.85  ? 136 THR F O   1 
ATOM   18792 C CB  . THR F 1 136 ? 26.544  76.196  22.682  1.00 25.72  ? 136 THR F CB  1 
ATOM   18793 O OG1 . THR F 1 136 ? 26.894  74.911  22.175  1.00 26.13  ? 136 THR F OG1 1 
ATOM   18794 C CG2 . THR F 1 136 ? 25.907  77.017  21.580  1.00 26.72  ? 136 THR F CG2 1 
ATOM   18795 N N   . HIS F 1 137 ? 27.736  79.305  22.939  1.00 25.14  ? 137 HIS F N   1 
ATOM   18796 C CA  . HIS F 1 137 ? 27.461  80.690  23.276  1.00 22.31  ? 137 HIS F CA  1 
ATOM   18797 C C   . HIS F 1 137 ? 25.963  80.869  23.531  1.00 24.58  ? 137 HIS F C   1 
ATOM   18798 O O   . HIS F 1 137 ? 25.120  80.293  22.829  1.00 21.72  ? 137 HIS F O   1 
ATOM   18799 C CB  . HIS F 1 137 ? 27.951  81.624  22.173  1.00 20.40  ? 137 HIS F CB  1 
ATOM   18800 C CG  . HIS F 1 137 ? 27.894  83.057  22.535  1.00 19.26  ? 137 HIS F CG  1 
ATOM   18801 N ND1 . HIS F 1 137 ? 26.719  83.777  22.514  1.00 20.19  ? 137 HIS F ND1 1 
ATOM   18802 C CD2 . HIS F 1 137 ? 28.840  83.889  22.980  1.00 18.95  ? 137 HIS F CD2 1 
ATOM   18803 C CE1 . HIS F 1 137 ? 26.952  85.025  22.931  1.00 20.53  ? 137 HIS F CE1 1 
ATOM   18804 N NE2 . HIS F 1 137 ? 28.237  85.112  23.220  1.00 22.45  ? 137 HIS F NE2 1 
ATOM   18805 N N   . PRO F 1 138 ? 25.598  81.659  24.565  1.00 22.42  ? 138 PRO F N   1 
ATOM   18806 C CA  . PRO F 1 138 ? 24.204  81.829  24.922  1.00 24.54  ? 138 PRO F CA  1 
ATOM   18807 C C   . PRO F 1 138 ? 23.300  82.293  23.779  1.00 27.23  ? 138 PRO F C   1 
ATOM   18808 O O   . PRO F 1 138 ? 22.123  81.921  23.741  1.00 26.27  ? 138 PRO F O   1 
ATOM   18809 C CB  . PRO F 1 138 ? 24.290  82.854  26.074  1.00 24.47  ? 138 PRO F CB  1 
ATOM   18810 C CG  . PRO F 1 138 ? 25.618  82.563  26.690  1.00 24.26  ? 138 PRO F CG  1 
ATOM   18811 C CD  . PRO F 1 138 ? 26.510  82.336  25.495  1.00 23.29  ? 138 PRO F CD  1 
ATOM   18812 N N   . MET F 1 139 ? 23.838  83.140  22.888  1.00 26.64  ? 139 MET F N   1 
ATOM   18813 C CA  . MET F 1 139 ? 23.012  83.751  21.863  1.00 24.02  ? 139 MET F CA  1 
ATOM   18814 C C   . MET F 1 139 ? 22.651  82.705  20.822  1.00 23.76  ? 139 MET F C   1 
ATOM   18815 O O   . MET F 1 139 ? 21.566  82.792  20.265  1.00 29.47  ? 139 MET F O   1 
ATOM   18816 C CB  . MET F 1 139 ? 23.659  84.973  21.217  1.00 22.39  ? 139 MET F CB  1 
ATOM   18817 C CG  . MET F 1 139 ? 23.506  86.223  22.031  1.00 22.12  ? 139 MET F CG  1 
ATOM   18818 S SD  . MET F 1 139 ? 21.776  86.679  22.272  1.00 23.27  ? 139 MET F SD  1 
ATOM   18819 C CE  . MET F 1 139 ? 21.176  87.210  20.667  1.00 21.72  ? 139 MET F CE  1 
ATOM   18820 N N   . THR F 1 140 ? 23.521  81.716  20.612  1.00 21.77  ? 140 THR F N   1 
ATOM   18821 C CA  . THR F 1 140 ? 23.230  80.583  19.736  1.00 21.36  ? 140 THR F CA  1 
ATOM   18822 C C   . THR F 1 140 ? 22.158  79.683  20.366  1.00 22.73  ? 140 THR F C   1 
ATOM   18823 O O   . THR F 1 140 ? 21.261  79.208  19.673  1.00 22.34  ? 140 THR F O   1 
ATOM   18824 C CB  . THR F 1 140 ? 24.541  79.836  19.478  1.00 20.78  ? 140 THR F CB  1 
ATOM   18825 O OG1 . THR F 1 140 ? 25.385  80.817  18.888  1.00 21.19  ? 140 THR F OG1 1 
ATOM   18826 C CG2 . THR F 1 140 ? 24.427  78.690  18.497  1.00 21.08  ? 140 THR F CG2 1 
ATOM   18827 N N   . MET F 1 141 ? 22.284  79.418  21.683  1.00 24.21  ? 141 MET F N   1 
ATOM   18828 C CA  . MET F 1 141 ? 21.325  78.636  22.438  1.00 23.01  ? 141 MET F CA  1 
ATOM   18829 C C   . MET F 1 141 ? 19.955  79.309  22.382  1.00 24.90  ? 141 MET F C   1 
ATOM   18830 O O   . MET F 1 141 ? 18.969  78.631  22.135  1.00 26.07  ? 141 MET F O   1 
ATOM   18831 C CB  . MET F 1 141 ? 21.750  78.531  23.902  1.00 24.41  ? 141 MET F CB  1 
ATOM   18832 C CG  . MET F 1 141 ? 22.838  77.513  24.173  1.00 25.77  ? 141 MET F CG  1 
ATOM   18833 S SD  . MET F 1 141 ? 23.126  77.357  25.948  1.00 26.76  ? 141 MET F SD  1 
ATOM   18834 C CE  . MET F 1 141 ? 24.497  76.191  25.929  1.00 29.66  ? 141 MET F CE  1 
ATOM   18835 N N   . PHE F 1 142 ? 19.920  80.637  22.609  1.00 22.10  ? 142 PHE F N   1 
ATOM   18836 C CA  . PHE F 1 142 ? 18.698  81.406  22.635  1.00 21.31  ? 142 PHE F CA  1 
ATOM   18837 C C   . PHE F 1 142 ? 17.985  81.302  21.293  1.00 23.77  ? 142 PHE F C   1 
ATOM   18838 O O   . PHE F 1 142 ? 16.829  80.902  21.208  1.00 24.32  ? 142 PHE F O   1 
ATOM   18839 C CB  . PHE F 1 142 ? 19.058  82.858  22.917  1.00 21.74  ? 142 PHE F CB  1 
ATOM   18840 C CG  . PHE F 1 142 ? 17.863  83.715  23.282  1.00 22.96  ? 142 PHE F CG  1 
ATOM   18841 C CD1 . PHE F 1 142 ? 16.896  83.253  24.170  1.00 24.51  ? 142 PHE F CD1 1 
ATOM   18842 C CD2 . PHE F 1 142 ? 17.743  85.006  22.804  1.00 24.28  ? 142 PHE F CD2 1 
ATOM   18843 C CE1 . PHE F 1 142 ? 15.850  84.062  24.557  1.00 22.57  ? 142 PHE F CE1 1 
ATOM   18844 C CE2 . PHE F 1 142 ? 16.669  85.810  23.179  1.00 23.35  ? 142 PHE F CE2 1 
ATOM   18845 C CZ  . PHE F 1 142 ? 15.727  85.334  24.042  1.00 22.34  ? 142 PHE F CZ  1 
ATOM   18846 N N   . ALA F 1 143 ? 18.699  81.629  20.226  1.00 23.62  ? 143 ALA F N   1 
ATOM   18847 C CA  . ALA F 1 143 ? 18.129  81.575  18.891  1.00 25.56  ? 143 ALA F CA  1 
ATOM   18848 C C   . ALA F 1 143 ? 17.614  80.174  18.548  1.00 24.63  ? 143 ALA F C   1 
ATOM   18849 O O   . ALA F 1 143 ? 16.552  80.015  17.966  1.00 25.25  ? 143 ALA F O   1 
ATOM   18850 C CB  . ALA F 1 143 ? 19.184  82.021  17.903  1.00 27.45  ? 143 ALA F CB  1 
ATOM   18851 N N   . ALA F 1 144 ? 18.372  79.144  18.896  1.00 22.82  ? 144 ALA F N   1 
ATOM   18852 C CA  . ALA F 1 144 ? 17.978  77.792  18.542  1.00 22.69  ? 144 ALA F CA  1 
ATOM   18853 C C   . ALA F 1 144 ? 16.703  77.360  19.264  1.00 24.08  ? 144 ALA F C   1 
ATOM   18854 O O   . ALA F 1 144 ? 15.871  76.637  18.717  1.00 24.76  ? 144 ALA F O   1 
ATOM   18855 C CB  . ALA F 1 144 ? 19.116  76.837  18.839  1.00 22.95  ? 144 ALA F CB  1 
ATOM   18856 N N   . GLY F 1 145 ? 16.567  77.737  20.527  1.00 24.84  ? 145 GLY F N   1 
ATOM   18857 C CA  . GLY F 1 145 ? 15.398  77.308  21.267  1.00 25.83  ? 145 GLY F CA  1 
ATOM   18858 C C   . GLY F 1 145 ? 14.158  77.984  20.696  1.00 27.82  ? 145 GLY F C   1 
ATOM   18859 O O   . GLY F 1 145 ? 13.134  77.341  20.461  1.00 29.47  ? 145 GLY F O   1 
ATOM   18860 N N   . ILE F 1 146 ? 14.298  79.289  20.451  1.00 27.21  ? 146 ILE F N   1 
ATOM   18861 C CA  . ILE F 1 146 ? 13.228  80.062  19.866  1.00 27.01  ? 146 ILE F CA  1 
ATOM   18862 C C   . ILE F 1 146 ? 12.850  79.361  18.575  1.00 26.04  ? 146 ILE F C   1 
ATOM   18863 O O   . ILE F 1 146 ? 11.680  79.071  18.344  1.00 28.46  ? 146 ILE F O   1 
ATOM   18864 C CB  . ILE F 1 146 ? 13.626  81.534  19.653  1.00 26.09  ? 146 ILE F CB  1 
ATOM   18865 C CG1 . ILE F 1 146 ? 13.903  82.220  20.972  1.00 24.37  ? 146 ILE F CG1 1 
ATOM   18866 C CG2 . ILE F 1 146 ? 12.568  82.290  18.841  1.00 25.54  ? 146 ILE F CG2 1 
ATOM   18867 C CD1 . ILE F 1 146 ? 14.786  83.441  20.826  1.00 25.70  ? 146 ILE F CD1 1 
ATOM   18868 N N   . LEU F 1 147 ? 13.855  79.007  17.789  1.00 25.15  ? 147 LEU F N   1 
ATOM   18869 C CA  . LEU F 1 147 ? 13.566  78.424  16.490  1.00 27.96  ? 147 LEU F CA  1 
ATOM   18870 C C   . LEU F 1 147 ? 12.842  77.083  16.658  1.00 25.03  ? 147 LEU F C   1 
ATOM   18871 O O   . LEU F 1 147 ? 11.944  76.789  15.902  1.00 23.92  ? 147 LEU F O   1 
ATOM   18872 C CB  . LEU F 1 147 ? 14.835  78.284  15.646  1.00 28.34  ? 147 LEU F CB  1 
ATOM   18873 C CG  . LEU F 1 147 ? 14.635  77.761  14.216  1.00 28.58  ? 147 LEU F CG  1 
ATOM   18874 C CD1 . LEU F 1 147 ? 13.697  78.662  13.450  1.00 29.75  ? 147 LEU F CD1 1 
ATOM   18875 C CD2 . LEU F 1 147 ? 15.947  77.651  13.464  1.00 29.57  ? 147 LEU F CD2 1 
ATOM   18876 N N   . ALA F 1 148 ? 13.220  76.259  17.632  1.00 26.14  ? 148 ALA F N   1 
ATOM   18877 C CA  . ALA F 1 148 ? 12.616  74.943  17.773  1.00 27.95  ? 148 ALA F CA  1 
ATOM   18878 C C   . ALA F 1 148 ? 11.114  75.073  17.978  1.00 27.44  ? 148 ALA F C   1 
ATOM   18879 O O   . ALA F 1 148 ? 10.350  74.232  17.526  1.00 26.75  ? 148 ALA F O   1 
ATOM   18880 C CB  . ALA F 1 148 ? 13.224  74.210  18.942  1.00 28.44  ? 148 ALA F CB  1 
ATOM   18881 N N   . MET F 1 149 ? 10.727  76.137  18.683  1.00 26.22  ? 149 MET F N   1 
ATOM   18882 C CA  . MET F 1 149 ? 9.353   76.363  19.074  1.00 28.55  ? 149 MET F CA  1 
ATOM   18883 C C   . MET F 1 149 ? 8.483   76.798  17.879  1.00 28.65  ? 149 MET F C   1 
ATOM   18884 O O   . MET F 1 149 ? 7.262   76.886  17.996  1.00 27.22  ? 149 MET F O   1 
ATOM   18885 C CB  . MET F 1 149 ? 9.344   77.402  20.206  1.00 29.74  ? 149 MET F CB  1 
ATOM   18886 C CG  . MET F 1 149 ? 8.036   77.489  20.970  1.00 29.85  ? 149 MET F CG  1 
ATOM   18887 S SD  . MET F 1 149 ? 8.118   78.450  22.493  1.00 28.27  ? 149 MET F SD  1 
ATOM   18888 C CE  . MET F 1 149 ? 6.404   78.439  23.019  1.00 26.37  ? 149 MET F CE  1 
ATOM   18889 N N   . GLN F 1 150 ? 9.098   77.068  16.720  1.00 30.88  ? 150 GLN F N   1 
ATOM   18890 C CA  . GLN F 1 150 ? 8.377   77.349  15.488  1.00 29.73  ? 150 GLN F CA  1 
ATOM   18891 C C   . GLN F 1 150 ? 7.297   76.294  15.251  1.00 31.21  ? 150 GLN F C   1 
ATOM   18892 O O   . GLN F 1 150 ? 6.231   76.624  14.739  1.00 32.83  ? 150 GLN F O   1 
ATOM   18893 C CB  . GLN F 1 150 ? 9.342   77.394  14.311  1.00 28.09  ? 150 GLN F CB  1 
ATOM   18894 C CG  . GLN F 1 150 ? 8.758   77.936  13.010  1.00 28.21  ? 150 GLN F CG  1 
ATOM   18895 C CD  . GLN F 1 150 ? 7.967   76.918  12.209  1.00 28.47  ? 150 GLN F CD  1 
ATOM   18896 O OE1 . GLN F 1 150 ? 8.289   75.719  12.137  1.00 27.30  ? 150 GLN F OE1 1 
ATOM   18897 N NE2 . GLN F 1 150 ? 6.903   77.406  11.592  1.00 25.02  ? 150 GLN F NE2 1 
ATOM   18898 N N   . ARG F 1 151 ? 7.540   75.051  15.686  1.00 29.26  ? 151 ARG F N   1 
ATOM   18899 C CA  . ARG F 1 151 ? 6.559   73.987  15.551  1.00 29.24  ? 151 ARG F CA  1 
ATOM   18900 C C   . ARG F 1 151 ? 5.182   74.419  16.065  1.00 28.46  ? 151 ARG F C   1 
ATOM   18901 O O   . ARG F 1 151 ? 4.193   73.924  15.556  1.00 26.72  ? 151 ARG F O   1 
ATOM   18902 C CB  . ARG F 1 151 ? 6.929   72.686  16.277  1.00 30.30  ? 151 ARG F CB  1 
ATOM   18903 C CG  . ARG F 1 151 ? 6.007   71.495  16.036  1.00 30.11  ? 151 ARG F CG  1 
ATOM   18904 C CD  . ARG F 1 151 ? 6.363   70.360  16.989  1.00 34.36  ? 151 ARG F CD  1 
ATOM   18905 N NE  . ARG F 1 151 ? 5.473   69.186  16.968  1.00 37.89  ? 151 ARG F NE  1 
ATOM   18906 C CZ  . ARG F 1 151 ? 4.477   68.920  17.824  1.00 33.81  ? 151 ARG F CZ  1 
ATOM   18907 N NH1 . ARG F 1 151 ? 4.055   69.813  18.723  1.00 31.90  ? 151 ARG F NH1 1 
ATOM   18908 N NH2 . ARG F 1 151 ? 3.865   67.759  17.721  1.00 35.98  ? 151 ARG F NH2 1 
ATOM   18909 N N   . GLU F 1 152 ? 5.116   75.303  17.068  1.00 29.48  ? 152 GLU F N   1 
ATOM   18910 C CA  . GLU F 1 152 ? 3.858   75.698  17.691  1.00 29.63  ? 152 GLU F CA  1 
ATOM   18911 C C   . GLU F 1 152 ? 3.298   76.997  17.074  1.00 28.63  ? 152 GLU F C   1 
ATOM   18912 O O   . GLU F 1 152 ? 2.428   77.630  17.683  1.00 27.15  ? 152 GLU F O   1 
ATOM   18913 C CB  . GLU F 1 152 ? 3.990   75.935  19.206  1.00 28.81  ? 152 GLU F CB  1 
ATOM   18914 C CG  . GLU F 1 152 ? 4.656   74.810  19.979  1.00 27.90  ? 152 GLU F CG  1 
ATOM   18915 C CD  . GLU F 1 152 ? 4.038   73.477  19.658  1.00 29.11  ? 152 GLU F CD  1 
ATOM   18916 O OE1 . GLU F 1 152 ? 4.781   72.480  19.420  1.00 26.33  ? 152 GLU F OE1 1 
ATOM   18917 O OE2 . GLU F 1 152 ? 2.778   73.484  19.675  1.00 28.20  ? 152 GLU F OE2 1 
ATOM   18918 N N   . SER F 1 153 ? 3.791   77.430  15.897  1.00 25.34  ? 153 SER F N   1 
ATOM   18919 C CA  . SER F 1 153 ? 3.344   78.701  15.352  1.00 24.10  ? 153 SER F CA  1 
ATOM   18920 C C   . SER F 1 153 ? 1.897   78.567  14.871  1.00 28.16  ? 153 SER F C   1 
ATOM   18921 O O   . SER F 1 153 ? 1.543   77.643  14.121  1.00 27.07  ? 153 SER F O   1 
ATOM   18922 C CB  . SER F 1 153 ? 4.199   79.174  14.240  1.00 23.68  ? 153 SER F CB  1 
ATOM   18923 O OG  . SER F 1 153 ? 3.642   80.350  13.664  1.00 24.05  ? 153 SER F OG  1 
ATOM   18924 N N   . VAL F 1 154 ? 1.075   79.503  15.337  1.00 26.26  ? 154 VAL F N   1 
ATOM   18925 C CA  . VAL F 1 154 ? -0.290  79.632  14.890  1.00 28.96  ? 154 VAL F CA  1 
ATOM   18926 C C   . VAL F 1 154 ? -0.266  80.263  13.502  1.00 28.68  ? 154 VAL F C   1 
ATOM   18927 O O   . VAL F 1 154 ? -1.084  79.932  12.649  1.00 28.22  ? 154 VAL F O   1 
ATOM   18928 C CB  . VAL F 1 154 ? -1.095  80.475  15.903  1.00 33.58  ? 154 VAL F CB  1 
ATOM   18929 C CG1 . VAL F 1 154 ? -2.497  80.788  15.420  1.00 32.34  ? 154 VAL F CG1 1 
ATOM   18930 C CG2 . VAL F 1 154 ? -1.143  79.823  17.295  1.00 35.69  ? 154 VAL F CG2 1 
ATOM   18931 N N   . PHE F 1 155 ? 0.667   81.177  13.247  1.00 27.61  ? 155 PHE F N   1 
ATOM   18932 C CA  . PHE F 1 155 ? 0.622   81.852  11.964  1.00 26.89  ? 155 PHE F CA  1 
ATOM   18933 C C   . PHE F 1 155 ? 0.957   80.838  10.869  1.00 28.17  ? 155 PHE F C   1 
ATOM   18934 O O   . PHE F 1 155 ? 0.329   80.814  9.818   1.00 30.68  ? 155 PHE F O   1 
ATOM   18935 C CB  . PHE F 1 155 ? 1.500   83.099  12.018  1.00 26.45  ? 155 PHE F CB  1 
ATOM   18936 C CG  . PHE F 1 155 ? 1.547   83.857  10.703  1.00 27.24  ? 155 PHE F CG  1 
ATOM   18937 C CD1 . PHE F 1 155 ? 2.296   83.382  9.634   1.00 27.40  ? 155 PHE F CD1 1 
ATOM   18938 C CD2 . PHE F 1 155 ? 0.852   85.052  10.543  1.00 30.78  ? 155 PHE F CD2 1 
ATOM   18939 C CE1 . PHE F 1 155 ? 2.337   84.081  8.435   1.00 31.92  ? 155 PHE F CE1 1 
ATOM   18940 C CE2 . PHE F 1 155 ? 0.896   85.756  9.338   1.00 28.82  ? 155 PHE F CE2 1 
ATOM   18941 C CZ  . PHE F 1 155 ? 1.631   85.267  8.290   1.00 29.76  ? 155 PHE F CZ  1 
ATOM   18942 N N   . ALA F 1 156 ? 1.950   79.985  11.101  1.00 28.50  ? 156 ALA F N   1 
ATOM   18943 C CA  . ALA F 1 156 ? 2.365   79.078  10.052  1.00 28.79  ? 156 ALA F CA  1 
ATOM   18944 C C   . ALA F 1 156 ? 1.293   78.018  9.846   1.00 32.97  ? 156 ALA F C   1 
ATOM   18945 O O   . ALA F 1 156 ? 1.085   77.604  8.714   1.00 35.77  ? 156 ALA F O   1 
ATOM   18946 C CB  . ALA F 1 156 ? 3.707   78.465  10.328  1.00 26.93  ? 156 ALA F CB  1 
ATOM   18947 N N   . LYS F 1 157 ? 0.612   77.590  10.919  1.00 34.89  ? 157 LYS F N   1 
ATOM   18948 C CA  . LYS F 1 157 ? -0.460  76.610  10.771  1.00 40.05  ? 157 LYS F CA  1 
ATOM   18949 C C   . LYS F 1 157 ? -1.647  77.241  10.027  1.00 40.49  ? 157 LYS F C   1 
ATOM   18950 O O   . LYS F 1 157 ? -2.216  76.604  9.146   1.00 38.69  ? 157 LYS F O   1 
ATOM   18951 C CB  . LYS F 1 157 ? -0.928  76.011  12.107  1.00 43.33  ? 157 LYS F CB  1 
ATOM   18952 C CG  . LYS F 1 157 ? -1.855  74.808  12.013  1.00 52.11  ? 157 LYS F CG  1 
ATOM   18953 C CD  . LYS F 1 157 ? -2.685  74.521  13.268  1.00 63.98  ? 157 LYS F CD  1 
ATOM   18954 C CE  . LYS F 1 157 ? -3.374  73.171  13.226  1.00 70.68  ? 157 LYS F CE  1 
ATOM   18955 N NZ  . LYS F 1 157 ? -4.415  73.004  14.245  1.00 75.85  ? 157 LYS F NZ  1 
ATOM   18956 N N   . ARG F 1 158 ? -2.007  78.488  10.373  1.00 39.89  ? 158 ARG F N   1 
ATOM   18957 C CA  . ARG F 1 158 ? -3.162  79.153  9.789   1.00 44.77  ? 158 ARG F CA  1 
ATOM   18958 C C   . ARG F 1 158 ? -2.832  79.513  8.343   1.00 44.95  ? 158 ARG F C   1 
ATOM   18959 O O   . ARG F 1 158 ? -3.701  79.397  7.481   1.00 47.19  ? 158 ARG F O   1 
ATOM   18960 C CB  . ARG F 1 158 ? -3.743  80.310  10.630  1.00 53.12  ? 158 ARG F CB  1 
ATOM   18961 C CG  . ARG F 1 158 ? -5.051  80.007  11.367  1.00 55.29  ? 158 ARG F CG  1 
ATOM   18962 C CD  . ARG F 1 158 ? -5.204  80.624  12.771  1.00 67.06  ? 158 ARG F CD  1 
ATOM   18963 N NE  . ARG F 1 158 ? -5.487  82.062  12.978  1.00 75.81  ? 158 ARG F NE  1 
ATOM   18964 C CZ  . ARG F 1 158 ? -5.644  82.660  14.190  1.00 62.79  ? 158 ARG F CZ  1 
ATOM   18965 N NH1 . ARG F 1 158 ? -5.603  81.949  15.307  1.00 59.28  ? 158 ARG F NH1 1 
ATOM   18966 N NH2 . ARG F 1 158 ? -5.856  83.960  14.297  1.00 54.57  ? 158 ARG F NH2 1 
ATOM   18967 N N   . TYR F 1 159 ? -1.569  79.848  8.045   1.00 40.48  ? 159 TYR F N   1 
ATOM   18968 C CA  . TYR F 1 159 ? -1.225  80.202  6.677   1.00 37.32  ? 159 TYR F CA  1 
ATOM   18969 C C   . TYR F 1 159 ? -1.345  78.977  5.768   1.00 37.81  ? 159 TYR F C   1 
ATOM   18970 O O   . TYR F 1 159 ? -1.817  79.107  4.643   1.00 43.48  ? 159 TYR F O   1 
ATOM   18971 C CB  . TYR F 1 159 ? 0.157   80.823  6.468   1.00 37.89  ? 159 TYR F CB  1 
ATOM   18972 C CG  . TYR F 1 159 ? 0.389   81.247  5.022   1.00 34.18  ? 159 TYR F CG  1 
ATOM   18973 C CD1 . TYR F 1 159 ? 0.823   80.318  4.078   1.00 33.24  ? 159 TYR F CD1 1 
ATOM   18974 C CD2 . TYR F 1 159 ? 0.163   82.559  4.603   1.00 31.29  ? 159 TYR F CD2 1 
ATOM   18975 C CE1 . TYR F 1 159 ? 1.028   80.672  2.756   1.00 33.55  ? 159 TYR F CE1 1 
ATOM   18976 C CE2 . TYR F 1 159 ? 0.374   82.930  3.281   1.00 31.67  ? 159 TYR F CE2 1 
ATOM   18977 C CZ  . TYR F 1 159 ? 0.801   81.980  2.360   1.00 34.38  ? 159 TYR F CZ  1 
ATOM   18978 O OH  . TYR F 1 159 ? 1.011   82.247  1.038   1.00 41.64  ? 159 TYR F OH  1 
ATOM   18979 N N   . GLU F 1 160 ? -0.912  77.809  6.255   1.00 38.14  ? 160 GLU F N   1 
ATOM   18980 C CA  . GLU F 1 160 ? -0.906  76.568  5.500   1.00 40.55  ? 160 GLU F CA  1 
ATOM   18981 C C   . GLU F 1 160 ? -2.350  76.141  5.230   1.00 43.77  ? 160 GLU F C   1 
ATOM   18982 O O   . GLU F 1 160 ? -2.629  75.569  4.181   1.00 40.58  ? 160 GLU F O   1 
ATOM   18983 C CB  . GLU F 1 160 ? -0.066  75.546  6.274   1.00 45.96  ? 160 GLU F CB  1 
ATOM   18984 C CG  . GLU F 1 160 ? 0.427   74.352  5.464   1.00 50.76  ? 160 GLU F CG  1 
ATOM   18985 C CD  . GLU F 1 160 ? -0.428  73.096  5.552   1.00 67.08  ? 160 GLU F CD  1 
ATOM   18986 O OE1 . GLU F 1 160 ? 0.100   71.993  5.256   1.00 76.73  ? 160 GLU F OE1 1 
ATOM   18987 O OE2 . GLU F 1 160 ? -1.628  73.204  5.898   1.00 72.76  ? 160 GLU F OE2 1 
ATOM   18988 N N   . GLU F 1 161 ? -3.274  76.453  6.156   1.00 47.67  ? 161 GLU F N   1 
ATOM   18989 C CA  . GLU F 1 161 ? -4.667  76.020  6.044   1.00 51.25  ? 161 GLU F CA  1 
ATOM   18990 C C   . GLU F 1 161 ? -5.411  76.893  5.037   1.00 50.38  ? 161 GLU F C   1 
ATOM   18991 O O   . GLU F 1 161 ? -6.423  76.469  4.499   1.00 62.39  ? 161 GLU F O   1 
ATOM   18992 C CB  . GLU F 1 161 ? -5.454  76.055  7.362   1.00 49.24  ? 161 GLU F CB  1 
ATOM   18993 C CG  . GLU F 1 161 ? -5.090  74.972  8.385   1.00 47.29  ? 161 GLU F CG  1 
ATOM   18994 C CD  . GLU F 1 161 ? -5.547  75.228  9.827   1.00 46.83  ? 161 GLU F CD  1 
ATOM   18995 O OE1 . GLU F 1 161 ? -5.418  74.331  10.686  1.00 46.86  ? 161 GLU F OE1 1 
ATOM   18996 O OE2 . GLU F 1 161 ? -6.009  76.341  10.125  1.00 43.83  ? 161 GLU F OE2 1 
ATOM   18997 N N   . GLY F 1 162 ? -4.894  78.093  4.773   1.00 45.99  ? 162 GLY F N   1 
ATOM   18998 C CA  . GLY F 1 162 ? -5.624  79.122  4.056   1.00 42.01  ? 162 GLY F CA  1 
ATOM   18999 C C   . GLY F 1 162 ? -6.221  80.107  5.052   1.00 40.08  ? 162 GLY F C   1 
ATOM   19000 O O   . GLY F 1 162 ? -7.006  79.717  5.901   1.00 49.03  ? 162 GLY F O   1 
ATOM   19001 N N   . MET F 1 163 ? -5.770  81.353  5.013   1.00 38.81  ? 163 MET F N   1 
ATOM   19002 C CA  . MET F 1 163 ? -6.313  82.391  5.876   1.00 42.52  ? 163 MET F CA  1 
ATOM   19003 C C   . MET F 1 163 ? -6.197  83.700  5.098   1.00 45.68  ? 163 MET F C   1 
ATOM   19004 O O   . MET F 1 163 ? -5.302  83.847  4.268   1.00 45.50  ? 163 MET F O   1 
ATOM   19005 C CB  . MET F 1 163 ? -5.658  82.446  7.276   1.00 40.58  ? 163 MET F CB  1 
ATOM   19006 C CG  . MET F 1 163 ? -4.274  83.114  7.385   1.00 43.32  ? 163 MET F CG  1 
ATOM   19007 S SD  . MET F 1 163 ? -3.743  83.822  8.976   1.00 44.14  ? 163 MET F SD  1 
ATOM   19008 C CE  . MET F 1 163 ? -1.998  83.418  8.781   1.00 38.97  ? 163 MET F CE  1 
ATOM   19009 N N   . ARG F 1 164 ? -7.120  84.638  5.333   1.00 48.06  ? 164 ARG F N   1 
ATOM   19010 C CA  . ARG F 1 164 ? -7.092  85.868  4.565   1.00 51.13  ? 164 ARG F CA  1 
ATOM   19011 C C   . ARG F 1 164 ? -5.970  86.739  5.119   1.00 47.14  ? 164 ARG F C   1 
ATOM   19012 O O   . ARG F 1 164 ? -5.552  86.568  6.253   1.00 44.18  ? 164 ARG F O   1 
ATOM   19013 C CB  . ARG F 1 164 ? -8.473  86.522  4.590   1.00 58.87  ? 164 ARG F CB  1 
ATOM   19014 C CG  . ARG F 1 164 ? -9.557  85.642  3.981   1.00 64.93  ? 164 ARG F CG  1 
ATOM   19015 C CD  . ARG F 1 164 ? -10.924 85.963  4.578   1.00 66.19  ? 164 ARG F CD  1 
ATOM   19016 N NE  . ARG F 1 164 ? -11.292 87.349  4.268   1.00 66.77  ? 164 ARG F NE  1 
ATOM   19017 C CZ  . ARG F 1 164 ? -11.623 88.311  5.125   1.00 64.85  ? 164 ARG F CZ  1 
ATOM   19018 N NH1 . ARG F 1 164 ? -11.694 88.092  6.424   1.00 70.65  ? 164 ARG F NH1 1 
ATOM   19019 N NH2 . ARG F 1 164 ? -11.890 89.513  4.661   1.00 68.01  ? 164 ARG F NH2 1 
ATOM   19020 N N   . ARG F 1 165 ? -5.500  87.681  4.306   1.00 50.11  ? 165 ARG F N   1 
ATOM   19021 C CA  . ARG F 1 165 ? -4.452  88.607  4.704   1.00 51.26  ? 165 ARG F CA  1 
ATOM   19022 C C   . ARG F 1 165 ? -4.891  89.431  5.930   1.00 51.90  ? 165 ARG F C   1 
ATOM   19023 O O   . ARG F 1 165 ? -4.047  89.899  6.703   1.00 47.38  ? 165 ARG F O   1 
ATOM   19024 C CB  . ARG F 1 165 ? -4.094  89.381  3.426   1.00 53.38  ? 165 ARG F CB  1 
ATOM   19025 C CG  . ARG F 1 165 ? -3.468  88.537  2.315   1.00 59.41  ? 165 ARG F CG  1 
ATOM   19026 C CD  . ARG F 1 165 ? -3.827  88.946  0.872   1.00 68.68  ? 165 ARG F CD  1 
ATOM   19027 N NE  . ARG F 1 165 ? -3.386  90.303  0.503   1.00 73.31  ? 165 ARG F NE  1 
ATOM   19028 C CZ  . ARG F 1 165 ? -4.164  91.361  0.224   1.00 64.06  ? 165 ARG F CZ  1 
ATOM   19029 N NH1 . ARG F 1 165 ? -5.478  91.237  0.223   1.00 57.19  ? 165 ARG F NH1 1 
ATOM   19030 N NH2 . ARG F 1 165 ? -3.625  92.543  -0.042  1.00 56.47  ? 165 ARG F NH2 1 
ATOM   19031 N N   . GLU F 1 166 ? -6.214  89.588  6.118   1.00 50.60  ? 166 GLU F N   1 
ATOM   19032 C CA  . GLU F 1 166 ? -6.789  90.450  7.146   1.00 51.92  ? 166 GLU F CA  1 
ATOM   19033 C C   . GLU F 1 166 ? -6.649  89.819  8.536   1.00 45.41  ? 166 GLU F C   1 
ATOM   19034 O O   . GLU F 1 166 ? -6.675  90.538  9.534   1.00 40.69  ? 166 GLU F O   1 
ATOM   19035 C CB  . GLU F 1 166 ? -8.256  90.785  6.826   1.00 57.82  ? 166 GLU F CB  1 
ATOM   19036 C CG  . GLU F 1 166 ? -8.454  91.845  5.735   1.00 66.87  ? 166 GLU F CG  1 
ATOM   19037 C CD  . GLU F 1 166 ? -8.221  91.485  4.258   1.00 69.96  ? 166 GLU F CD  1 
ATOM   19038 O OE1 . GLU F 1 166 ? -8.073  92.464  3.469   1.00 59.53  ? 166 GLU F OE1 1 
ATOM   19039 O OE2 . GLU F 1 166 ? -8.192  90.272  3.880   1.00 60.33  ? 166 GLU F OE2 1 
ATOM   19040 N N   . GLU F 1 167 ? -6.529  88.484  8.600   1.00 40.28  ? 167 GLU F N   1 
ATOM   19041 C CA  . GLU F 1 167 ? -6.343  87.791  9.865   1.00 48.96  ? 167 GLU F CA  1 
ATOM   19042 C C   . GLU F 1 167 ? -4.859  87.659  10.241  1.00 43.36  ? 167 GLU F C   1 
ATOM   19043 O O   . GLU F 1 167 ? -4.559  87.103  11.294  1.00 45.26  ? 167 GLU F O   1 
ATOM   19044 C CB  . GLU F 1 167 ? -6.946  86.387  9.816   1.00 58.91  ? 167 GLU F CB  1 
ATOM   19045 C CG  . GLU F 1 167 ? -8.440  86.343  9.492   1.00 77.96  ? 167 GLU F CG  1 
ATOM   19046 C CD  . GLU F 1 167 ? -8.861  84.995  8.913   1.00 89.46  ? 167 GLU F CD  1 
ATOM   19047 O OE1 . GLU F 1 167 ? -8.529  83.974  9.569   1.00 90.59  ? 167 GLU F OE1 1 
ATOM   19048 O OE2 . GLU F 1 167 ? -9.466  84.955  7.806   1.00 84.60  ? 167 GLU F OE2 1 
ATOM   19049 N N   . HIS F 1 168 ? -3.940  88.158  9.396   1.00 34.69  ? 168 HIS F N   1 
ATOM   19050 C CA  . HIS F 1 168 ? -2.506  88.022  9.619   1.00 33.23  ? 168 HIS F CA  1 
ATOM   19051 C C   . HIS F 1 168 ? -2.075  88.597  10.967  1.00 32.48  ? 168 HIS F C   1 
ATOM   19052 O O   . HIS F 1 168 ? -1.387  87.918  11.722  1.00 30.21  ? 168 HIS F O   1 
ATOM   19053 C CB  . HIS F 1 168 ? -1.684  88.677  8.502   1.00 32.16  ? 168 HIS F CB  1 
ATOM   19054 C CG  . HIS F 1 168 ? -1.577  87.828  7.285   1.00 32.07  ? 168 HIS F CG  1 
ATOM   19055 N ND1 . HIS F 1 168 ? -0.738  88.126  6.230   1.00 30.86  ? 168 HIS F ND1 1 
ATOM   19056 C CD2 . HIS F 1 168 ? -2.223  86.696  6.955   1.00 28.98  ? 168 HIS F CD2 1 
ATOM   19057 C CE1 . HIS F 1 168 ? -0.874  87.183  5.308   1.00 31.21  ? 168 HIS F CE1 1 
ATOM   19058 N NE2 . HIS F 1 168 ? -1.776  86.316  5.725   1.00 29.44  ? 168 HIS F NE2 1 
ATOM   19059 N N   . TRP F 1 169 ? -2.471  89.842  11.257  1.00 34.20  ? 169 TRP F N   1 
ATOM   19060 C CA  . TRP F 1 169 ? -2.034  90.537  12.460  1.00 31.68  ? 169 TRP F CA  1 
ATOM   19061 C C   . TRP F 1 169 ? -2.499  89.780  13.701  1.00 31.67  ? 169 TRP F C   1 
ATOM   19062 O O   . TRP F 1 169 ? -1.804  89.801  14.705  1.00 28.92  ? 169 TRP F O   1 
ATOM   19063 C CB  . TRP F 1 169 ? -2.518  91.999  12.481  1.00 34.84  ? 169 TRP F CB  1 
ATOM   19064 C CG  . TRP F 1 169 ? -3.990  92.195  12.763  1.00 36.39  ? 169 TRP F CG  1 
ATOM   19065 C CD1 . TRP F 1 169 ? -4.985  92.290  11.834  1.00 38.40  ? 169 TRP F CD1 1 
ATOM   19066 C CD2 . TRP F 1 169 ? -4.643  92.336  14.045  1.00 34.75  ? 169 TRP F CD2 1 
ATOM   19067 N NE1 . TRP F 1 169 ? -6.201  92.455  12.440  1.00 38.20  ? 169 TRP F NE1 1 
ATOM   19068 C CE2 . TRP F 1 169 ? -6.026  92.487  13.793  1.00 36.03  ? 169 TRP F CE2 1 
ATOM   19069 C CE3 . TRP F 1 169 ? -4.208  92.334  15.368  1.00 33.34  ? 169 TRP F CE3 1 
ATOM   19070 C CZ2 . TRP F 1 169 ? -6.964  92.640  14.806  1.00 35.27  ? 169 TRP F CZ2 1 
ATOM   19071 C CZ3 . TRP F 1 169 ? -5.139  92.503  16.369  1.00 34.99  ? 169 TRP F CZ3 1 
ATOM   19072 C CH2 . TRP F 1 169 ? -6.496  92.658  16.094  1.00 34.12  ? 169 TRP F CH2 1 
ATOM   19073 N N   . GLU F 1 170 ? -3.660  89.109  13.608  1.00 35.15  ? 170 GLU F N   1 
ATOM   19074 C CA  . GLU F 1 170 ? -4.240  88.346  14.707  1.00 34.13  ? 170 GLU F CA  1 
ATOM   19075 C C   . GLU F 1 170 ? -3.364  87.140  15.014  1.00 31.90  ? 170 GLU F C   1 
ATOM   19076 O O   . GLU F 1 170 ? -3.053  86.885  16.171  1.00 30.22  ? 170 GLU F O   1 
ATOM   19077 C CB  . GLU F 1 170 ? -5.689  87.943  14.402  1.00 36.37  ? 170 GLU F CB  1 
ATOM   19078 C CG  . GLU F 1 170 ? -6.631  89.151  14.261  1.00 40.11  ? 170 GLU F CG  1 
ATOM   19079 C CD  . GLU F 1 170 ? -8.118  88.899  14.004  1.00 42.19  ? 170 GLU F CD  1 
ATOM   19080 O OE1 . GLU F 1 170 ? -8.599  89.412  12.974  1.00 47.87  ? 170 GLU F OE1 1 
ATOM   19081 O OE2 . GLU F 1 170 ? -8.813  88.243  14.810  1.00 41.30  ? 170 GLU F OE2 1 
ATOM   19082 N N   . ALA F 1 171 ? -2.937  86.416  13.978  1.00 31.65  ? 171 ALA F N   1 
ATOM   19083 C CA  . ALA F 1 171 ? -2.107  85.244  14.201  1.00 29.68  ? 171 ALA F CA  1 
ATOM   19084 C C   . ALA F 1 171 ? -0.731  85.664  14.703  1.00 30.58  ? 171 ALA F C   1 
ATOM   19085 O O   . ALA F 1 171 ? -0.096  84.934  15.431  1.00 36.65  ? 171 ALA F O   1 
ATOM   19086 C CB  . ALA F 1 171 ? -1.986  84.430  12.945  1.00 27.63  ? 171 ALA F CB  1 
ATOM   19087 N N   . MET F 1 172 ? -0.266  86.834  14.286  1.00 32.18  ? 172 MET F N   1 
ATOM   19088 C CA  . MET F 1 172 ? 1.035   87.338  14.673  1.00 31.56  ? 172 MET F CA  1 
ATOM   19089 C C   . MET F 1 172 ? 0.998   87.731  16.157  1.00 31.85  ? 172 MET F C   1 
ATOM   19090 O O   . MET F 1 172 ? 1.977   87.535  16.881  1.00 29.67  ? 172 MET F O   1 
ATOM   19091 C CB  . MET F 1 172 ? 1.389   88.513  13.754  1.00 35.40  ? 172 MET F CB  1 
ATOM   19092 C CG  . MET F 1 172 ? 2.876   88.661  13.456  1.00 47.00  ? 172 MET F CG  1 
ATOM   19093 S SD  . MET F 1 172 ? 3.542   87.545  12.212  1.00 41.45  ? 172 MET F SD  1 
ATOM   19094 C CE  . MET F 1 172 ? 3.749   86.036  13.181  1.00 59.67  ? 172 MET F CE  1 
ATOM   19095 N N   . LEU F 1 173 ? -0.152  88.257  16.613  1.00 28.64  ? 173 LEU F N   1 
ATOM   19096 C CA  . LEU F 1 173 ? -0.334  88.704  17.987  1.00 29.13  ? 173 LEU F CA  1 
ATOM   19097 C C   . LEU F 1 173 ? -0.360  87.490  18.904  1.00 30.67  ? 173 LEU F C   1 
ATOM   19098 O O   . LEU F 1 173 ? 0.223   87.529  19.977  1.00 34.11  ? 173 LEU F O   1 
ATOM   19099 C CB  . LEU F 1 173 ? -1.616  89.521  18.175  1.00 29.27  ? 173 LEU F CB  1 
ATOM   19100 C CG  . LEU F 1 173 ? -1.931  89.945  19.613  1.00 30.01  ? 173 LEU F CG  1 
ATOM   19101 C CD1 . LEU F 1 173 ? -0.935  90.984  20.121  1.00 30.84  ? 173 LEU F CD1 1 
ATOM   19102 C CD2 . LEU F 1 173 ? -3.354  90.451  19.752  1.00 31.35  ? 173 LEU F CD2 1 
ATOM   19103 N N   . GLU F 1 174 ? -1.106  86.456  18.505  1.00 32.47  ? 174 GLU F N   1 
ATOM   19104 C CA  . GLU F 1 174 ? -1.240  85.237  19.287  1.00 31.69  ? 174 GLU F CA  1 
ATOM   19105 C C   . GLU F 1 174 ? 0.153   84.629  19.487  1.00 32.66  ? 174 GLU F C   1 
ATOM   19106 O O   . GLU F 1 174 ? 0.488   84.173  20.573  1.00 31.81  ? 174 GLU F O   1 
ATOM   19107 C CB  . GLU F 1 174 ? -2.252  84.328  18.575  1.00 30.81  ? 174 GLU F CB  1 
ATOM   19108 C CG  . GLU F 1 174 ? -2.711  83.088  19.348  1.00 32.66  ? 174 GLU F CG  1 
ATOM   19109 C CD  . GLU F 1 174 ? -3.403  83.315  20.695  1.00 37.23  ? 174 GLU F CD  1 
ATOM   19110 O OE1 . GLU F 1 174 ? -3.904  84.431  20.980  1.00 35.24  ? 174 GLU F OE1 1 
ATOM   19111 O OE2 . GLU F 1 174 ? -3.411  82.351  21.500  1.00 39.16  ? 174 GLU F OE2 1 
ATOM   19112 N N   . ASP F 1 175 ? 0.963   84.629  18.424  1.00 31.46  ? 175 ASP F N   1 
ATOM   19113 C CA  . ASP F 1 175 ? 2.261   83.980  18.426  1.00 29.86  ? 175 ASP F CA  1 
ATOM   19114 C C   . ASP F 1 175 ? 3.237   84.793  19.279  1.00 29.16  ? 175 ASP F C   1 
ATOM   19115 O O   . ASP F 1 175 ? 4.030   84.214  20.020  1.00 30.02  ? 175 ASP F O   1 
ATOM   19116 C CB  . ASP F 1 175 ? 2.815   83.853  17.014  1.00 27.09  ? 175 ASP F CB  1 
ATOM   19117 C CG  . ASP F 1 175 ? 2.488   82.592  16.230  1.00 25.69  ? 175 ASP F CG  1 
ATOM   19118 O OD1 . ASP F 1 175 ? 2.029   81.584  16.840  1.00 22.97  ? 175 ASP F OD1 1 
ATOM   19119 O OD2 . ASP F 1 175 ? 2.716   82.641  14.999  1.00 31.40  ? 175 ASP F OD2 1 
ATOM   19120 N N   . SER F 1 176 ? 3.205   86.121  19.098  1.00 24.55  ? 176 SER F N   1 
ATOM   19121 C CA  . SER F 1 176 ? 4.000   87.045  19.883  1.00 24.66  ? 176 SER F CA  1 
ATOM   19122 C C   . SER F 1 176 ? 3.757   86.859  21.387  1.00 24.99  ? 176 SER F C   1 
ATOM   19123 O O   . SER F 1 176 ? 4.698   86.889  22.163  1.00 25.66  ? 176 SER F O   1 
ATOM   19124 C CB  . SER F 1 176 ? 3.717   88.477  19.491  1.00 22.65  ? 176 SER F CB  1 
ATOM   19125 O OG  . SER F 1 176 ? 4.044   88.709  18.133  1.00 22.38  ? 176 SER F OG  1 
ATOM   19126 N N   . LEU F 1 177 ? 2.491   86.747  21.796  1.00 25.54  ? 177 LEU F N   1 
ATOM   19127 C CA  . LEU F 1 177 ? 2.120   86.555  23.191  1.00 26.12  ? 177 LEU F CA  1 
ATOM   19128 C C   . LEU F 1 177 ? 2.793   85.272  23.663  1.00 26.31  ? 177 LEU F C   1 
ATOM   19129 O O   . LEU F 1 177 ? 3.380   85.249  24.736  1.00 29.88  ? 177 LEU F O   1 
ATOM   19130 C CB  . LEU F 1 177 ? 0.601   86.476  23.410  1.00 25.97  ? 177 LEU F CB  1 
ATOM   19131 C CG  . LEU F 1 177 ? -0.216  87.753  23.180  1.00 28.15  ? 177 LEU F CG  1 
ATOM   19132 C CD1 . LEU F 1 177 ? -1.748  87.569  23.237  1.00 26.57  ? 177 LEU F CD1 1 
ATOM   19133 C CD2 . LEU F 1 177 ? 0.226   88.809  24.189  1.00 28.29  ? 177 LEU F CD2 1 
ATOM   19134 N N   . ASN F 1 178 ? 2.708   84.206  22.866  1.00 26.32  ? 178 ASN F N   1 
ATOM   19135 C CA  . ASN F 1 178 ? 3.268   82.931  23.286  1.00 29.82  ? 178 ASN F CA  1 
ATOM   19136 C C   . ASN F 1 178 ? 4.792   83.036  23.336  1.00 29.91  ? 178 ASN F C   1 
ATOM   19137 O O   . ASN F 1 178 ? 5.420   82.568  24.288  1.00 30.06  ? 178 ASN F O   1 
ATOM   19138 C CB  . ASN F 1 178 ? 2.823   81.783  22.389  1.00 30.91  ? 178 ASN F CB  1 
ATOM   19139 C CG  . ASN F 1 178 ? 1.358   81.439  22.558  1.00 32.84  ? 178 ASN F CG  1 
ATOM   19140 O OD1 . ASN F 1 178 ? 0.751   81.689  23.617  1.00 32.46  ? 178 ASN F OD1 1 
ATOM   19141 N ND2 . ASN F 1 178 ? 0.784   80.852  21.514  1.00 31.39  ? 178 ASN F ND2 1 
ATOM   19142 N N   . MET F 1 179 ? 5.384   83.684  22.329  1.00 26.79  ? 179 MET F N   1 
ATOM   19143 C CA  . MET F 1 179 ? 6.828   83.687  22.247  1.00 25.20  ? 179 MET F CA  1 
ATOM   19144 C C   . MET F 1 179 ? 7.378   84.571  23.359  1.00 22.97  ? 179 MET F C   1 
ATOM   19145 O O   . MET F 1 179 ? 8.337   84.184  24.003  1.00 22.50  ? 179 MET F O   1 
ATOM   19146 C CB  . MET F 1 179 ? 7.341   84.158  20.886  1.00 26.66  ? 179 MET F CB  1 
ATOM   19147 C CG  . MET F 1 179 ? 8.865   84.178  20.800  1.00 26.25  ? 179 MET F CG  1 
ATOM   19148 S SD  . MET F 1 179 ? 9.504   84.878  19.271  1.00 23.89  ? 179 MET F SD  1 
ATOM   19149 C CE  . MET F 1 179 ? 9.311   86.614  19.657  1.00 22.11  ? 179 MET F CE  1 
ATOM   19150 N N   . LEU F 1 180 ? 6.766   85.739  23.589  1.00 21.34  ? 180 LEU F N   1 
ATOM   19151 C CA  . LEU F 1 180 ? 7.277   86.654  24.594  1.00 21.29  ? 180 LEU F CA  1 
ATOM   19152 C C   . LEU F 1 180 ? 7.255   85.963  25.956  1.00 22.41  ? 180 LEU F C   1 
ATOM   19153 O O   . LEU F 1 180 ? 8.211   86.069  26.712  1.00 21.96  ? 180 LEU F O   1 
ATOM   19154 C CB  . LEU F 1 180 ? 6.479   87.947  24.622  1.00 22.24  ? 180 LEU F CB  1 
ATOM   19155 C CG  . LEU F 1 180 ? 6.792   88.953  23.514  1.00 24.17  ? 180 LEU F CG  1 
ATOM   19156 C CD1 . LEU F 1 180 ? 5.734   90.045  23.514  1.00 26.16  ? 180 LEU F CD1 1 
ATOM   19157 C CD2 . LEU F 1 180 ? 8.177   89.596  23.654  1.00 24.53  ? 180 LEU F CD2 1 
ATOM   19158 N N   . ALA F 1 181 ? 6.172   85.226  26.251  1.00 22.02  ? 181 ALA F N   1 
ATOM   19159 C CA  . ALA F 1 181 ? 6.076   84.453  27.482  1.00 21.30  ? 181 ALA F CA  1 
ATOM   19160 C C   . ALA F 1 181 ? 7.227   83.464  27.606  1.00 22.05  ? 181 ALA F C   1 
ATOM   19161 O O   . ALA F 1 181 ? 7.703   83.218  28.708  1.00 24.45  ? 181 ALA F O   1 
ATOM   19162 C CB  . ALA F 1 181 ? 4.741   83.736  27.565  1.00 20.58  ? 181 ALA F CB  1 
ATOM   19163 N N   . ALA F 1 182 ? 7.685   82.931  26.465  1.00 22.54  ? 182 ALA F N   1 
ATOM   19164 C CA  . ALA F 1 182 ? 8.654   81.857  26.447  1.00 20.73  ? 182 ALA F CA  1 
ATOM   19165 C C   . ALA F 1 182 ? 10.063  82.386  26.662  1.00 21.03  ? 182 ALA F C   1 
ATOM   19166 O O   . ALA F 1 182 ? 10.938  81.650  27.101  1.00 19.60  ? 182 ALA F O   1 
ATOM   19167 C CB  . ALA F 1 182 ? 8.565   81.108  25.143  1.00 20.20  ? 182 ALA F CB  1 
ATOM   19168 N N   . LEU F 1 183 ? 10.323  83.632  26.278  1.00 22.08  ? 183 LEU F N   1 
ATOM   19169 C CA  . LEU F 1 183 ? 11.709  84.059  26.167  1.00 22.40  ? 183 LEU F CA  1 
ATOM   19170 C C   . LEU F 1 183 ? 12.362  84.064  27.554  1.00 24.86  ? 183 LEU F C   1 
ATOM   19171 O O   . LEU F 1 183 ? 13.419  83.466  27.717  1.00 26.35  ? 183 LEU F O   1 
ATOM   19172 C CB  . LEU F 1 183 ? 11.782  85.395  25.437  1.00 23.95  ? 183 LEU F CB  1 
ATOM   19173 C CG  . LEU F 1 183 ? 11.298  85.390  23.975  1.00 24.37  ? 183 LEU F CG  1 
ATOM   19174 C CD1 . LEU F 1 183 ? 11.656  86.736  23.402  1.00 25.92  ? 183 LEU F CD1 1 
ATOM   19175 C CD2 . LEU F 1 183 ? 11.852  84.257  23.088  1.00 21.29  ? 183 LEU F CD2 1 
ATOM   19176 N N   . PRO F 1 184 ? 11.758  84.639  28.626  1.00 23.52  ? 184 PRO F N   1 
ATOM   19177 C CA  . PRO F 1 184 ? 12.343  84.545  29.968  1.00 23.65  ? 184 PRO F CA  1 
ATOM   19178 C C   . PRO F 1 184 ? 12.645  83.122  30.442  1.00 21.41  ? 184 PRO F C   1 
ATOM   19179 O O   . PRO F 1 184 ? 13.698  82.848  30.994  1.00 20.81  ? 184 PRO F O   1 
ATOM   19180 C CB  . PRO F 1 184 ? 11.299  85.241  30.870  1.00 25.03  ? 184 PRO F CB  1 
ATOM   19181 C CG  . PRO F 1 184 ? 10.556  86.174  29.943  1.00 25.81  ? 184 PRO F CG  1 
ATOM   19182 C CD  . PRO F 1 184 ? 10.508  85.416  28.614  1.00 25.40  ? 184 PRO F CD  1 
ATOM   19183 N N   . VAL F 1 185 ? 11.731  82.196  30.186  1.00 22.00  ? 185 VAL F N   1 
ATOM   19184 C CA  . VAL F 1 185 ? 11.928  80.803  30.541  1.00 21.41  ? 185 VAL F CA  1 
ATOM   19185 C C   . VAL F 1 185 ? 13.125  80.238  29.803  1.00 22.21  ? 185 VAL F C   1 
ATOM   19186 O O   . VAL F 1 185 ? 13.957  79.556  30.378  1.00 22.37  ? 185 VAL F O   1 
ATOM   19187 C CB  . VAL F 1 185 ? 10.665  79.987  30.238  1.00 23.31  ? 185 VAL F CB  1 
ATOM   19188 C CG1 . VAL F 1 185 ? 10.866  78.509  30.538  1.00 24.79  ? 185 VAL F CG1 1 
ATOM   19189 C CG2 . VAL F 1 185 ? 9.453   80.501  31.022  1.00 22.85  ? 185 VAL F CG2 1 
ATOM   19190 N N   . ILE F 1 186 ? 13.188  80.512  28.502  1.00 26.83  ? 186 ILE F N   1 
ATOM   19191 C CA  . ILE F 1 186 ? 14.254  79.989  27.660  1.00 26.22  ? 186 ILE F CA  1 
ATOM   19192 C C   . ILE F 1 186 ? 15.576  80.606  28.087  1.00 22.50  ? 186 ILE F C   1 
ATOM   19193 O O   . ILE F 1 186 ? 16.541  79.887  28.239  1.00 22.40  ? 186 ILE F O   1 
ATOM   19194 C CB  . ILE F 1 186 ? 13.955  80.202  26.156  1.00 26.52  ? 186 ILE F CB  1 
ATOM   19195 C CG1 . ILE F 1 186 ? 12.723  79.401  25.737  1.00 28.04  ? 186 ILE F CG1 1 
ATOM   19196 C CG2 . ILE F 1 186 ? 15.166  79.825  25.287  1.00 25.80  ? 186 ILE F CG2 1 
ATOM   19197 C CD1 . ILE F 1 186 ? 12.388  79.491  24.259  1.00 30.74  ? 186 ILE F CD1 1 
ATOM   19198 N N   . ALA F 1 187 ? 15.586  81.928  28.277  1.00 20.53  ? 187 ALA F N   1 
ATOM   19199 C CA  . ALA F 1 187 ? 16.782  82.642  28.663  1.00 22.66  ? 187 ALA F CA  1 
ATOM   19200 C C   . ALA F 1 187 ? 17.286  82.158  30.028  1.00 25.13  ? 187 ALA F C   1 
ATOM   19201 O O   . ALA F 1 187 ? 18.496  81.942  30.206  1.00 27.61  ? 187 ALA F O   1 
ATOM   19202 C CB  . ALA F 1 187 ? 16.498  84.135  28.650  1.00 22.54  ? 187 ALA F CB  1 
ATOM   19203 N N   . ALA F 1 188 ? 16.361  81.995  30.984  1.00 22.26  ? 188 ALA F N   1 
ATOM   19204 C CA  . ALA F 1 188 ? 16.732  81.540  32.307  1.00 24.91  ? 188 ALA F CA  1 
ATOM   19205 C C   . ALA F 1 188 ? 17.205  80.091  32.269  1.00 24.94  ? 188 ALA F C   1 
ATOM   19206 O O   . ALA F 1 188 ? 18.122  79.765  32.994  1.00 30.62  ? 188 ALA F O   1 
ATOM   19207 C CB  . ALA F 1 188 ? 15.607  81.743  33.288  1.00 26.75  ? 188 ALA F CB  1 
ATOM   19208 N N   . TYR F 1 189 ? 16.680  79.239  31.384  1.00 23.48  ? 189 TYR F N   1 
ATOM   19209 C CA  . TYR F 1 189 ? 17.175  77.875  31.322  1.00 23.80  ? 189 TYR F CA  1 
ATOM   19210 C C   . TYR F 1 189 ? 18.659  77.877  30.932  1.00 26.28  ? 189 TYR F C   1 
ATOM   19211 O O   . TYR F 1 189 ? 19.467  77.056  31.385  1.00 25.07  ? 189 TYR F O   1 
ATOM   19212 C CB  . TYR F 1 189 ? 16.347  77.040  30.339  1.00 26.62  ? 189 TYR F CB  1 
ATOM   19213 C CG  . TYR F 1 189 ? 16.623  75.541  30.412  1.00 25.05  ? 189 TYR F CG  1 
ATOM   19214 C CD1 . TYR F 1 189 ? 15.977  74.765  31.362  1.00 27.82  ? 189 TYR F CD1 1 
ATOM   19215 C CD2 . TYR F 1 189 ? 17.557  74.918  29.603  1.00 24.04  ? 189 TYR F CD2 1 
ATOM   19216 C CE1 . TYR F 1 189 ? 16.239  73.411  31.497  1.00 28.05  ? 189 TYR F CE1 1 
ATOM   19217 C CE2 . TYR F 1 189 ? 17.852  73.566  29.743  1.00 25.55  ? 189 TYR F CE2 1 
ATOM   19218 C CZ  . TYR F 1 189 ? 17.187  72.814  30.694  1.00 26.47  ? 189 TYR F CZ  1 
ATOM   19219 O OH  . TYR F 1 189 ? 17.363  71.490  30.901  1.00 29.76  ? 189 TYR F OH  1 
ATOM   19220 N N   . ILE F 1 190 ? 19.010  78.778  30.015  1.00 27.43  ? 190 ILE F N   1 
ATOM   19221 C CA  . ILE F 1 190 ? 20.366  78.849  29.488  1.00 25.79  ? 190 ILE F CA  1 
ATOM   19222 C C   . ILE F 1 190 ? 21.303  79.357  30.579  1.00 23.81  ? 190 ILE F C   1 
ATOM   19223 O O   . ILE F 1 190 ? 22.377  78.804  30.796  1.00 21.64  ? 190 ILE F O   1 
ATOM   19224 C CB  . ILE F 1 190 ? 20.358  79.745  28.236  1.00 24.81  ? 190 ILE F CB  1 
ATOM   19225 C CG1 . ILE F 1 190 ? 19.690  79.034  27.081  1.00 23.21  ? 190 ILE F CG1 1 
ATOM   19226 C CG2 . ILE F 1 190 ? 21.759  80.249  27.873  1.00 23.38  ? 190 ILE F CG2 1 
ATOM   19227 C CD1 . ILE F 1 190 ? 19.284  79.969  25.964  1.00 25.31  ? 190 ILE F CD1 1 
ATOM   19228 N N   . TYR F 1 191 ? 20.870  80.419  31.263  1.00 25.36  ? 191 TYR F N   1 
ATOM   19229 C CA  . TYR F 1 191 ? 21.620  80.972  32.382  1.00 26.06  ? 191 TYR F CA  1 
ATOM   19230 C C   . TYR F 1 191 ? 21.894  79.915  33.455  1.00 25.20  ? 191 TYR F C   1 
ATOM   19231 O O   . TYR F 1 191 ? 23.030  79.762  33.884  1.00 25.44  ? 191 TYR F O   1 
ATOM   19232 C CB  . TYR F 1 191 ? 20.868  82.136  33.016  1.00 26.78  ? 191 TYR F CB  1 
ATOM   19233 C CG  . TYR F 1 191 ? 21.737  82.894  33.998  1.00 28.68  ? 191 TYR F CG  1 
ATOM   19234 C CD1 . TYR F 1 191 ? 22.732  83.757  33.560  1.00 31.05  ? 191 TYR F CD1 1 
ATOM   19235 C CD2 . TYR F 1 191 ? 21.562  82.736  35.366  1.00 29.66  ? 191 TYR F CD2 1 
ATOM   19236 C CE1 . TYR F 1 191 ? 23.527  84.450  34.462  1.00 33.06  ? 191 TYR F CE1 1 
ATOM   19237 C CE2 . TYR F 1 191 ? 22.350  83.409  36.279  1.00 28.94  ? 191 TYR F CE2 1 
ATOM   19238 C CZ  . TYR F 1 191 ? 23.341  84.261  35.827  1.00 31.86  ? 191 TYR F CZ  1 
ATOM   19239 O OH  . TYR F 1 191 ? 24.096  84.923  36.740  1.00 27.23  ? 191 TYR F OH  1 
ATOM   19240 N N   . ARG F 1 192 ? 20.857  79.189  33.883  1.00 24.46  ? 192 ARG F N   1 
ATOM   19241 C CA  . ARG F 1 192 ? 20.982  78.198  34.945  1.00 24.78  ? 192 ARG F CA  1 
ATOM   19242 C C   . ARG F 1 192 ? 21.897  77.038  34.546  1.00 24.53  ? 192 ARG F C   1 
ATOM   19243 O O   . ARG F 1 192 ? 22.763  76.605  35.306  1.00 25.76  ? 192 ARG F O   1 
ATOM   19244 C CB  . ARG F 1 192 ? 19.600  77.648  35.331  1.00 24.03  ? 192 ARG F CB  1 
ATOM   19245 C CG  . ARG F 1 192 ? 18.676  78.669  35.985  1.00 25.19  ? 192 ARG F CG  1 
ATOM   19246 C CD  . ARG F 1 192 ? 19.281  79.458  37.140  1.00 24.68  ? 192 ARG F CD  1 
ATOM   19247 N NE  . ARG F 1 192 ? 19.501  78.557  38.260  1.00 25.00  ? 192 ARG F NE  1 
ATOM   19248 C CZ  . ARG F 1 192 ? 19.736  78.896  39.532  1.00 24.20  ? 192 ARG F CZ  1 
ATOM   19249 N NH1 . ARG F 1 192 ? 19.980  80.155  39.836  1.00 22.79  ? 192 ARG F NH1 1 
ATOM   19250 N NH2 . ARG F 1 192 ? 19.744  77.945  40.471  1.00 22.13  ? 192 ARG F NH2 1 
ATOM   19251 N N   . ARG F 1 193 ? 21.649  76.470  33.375  1.00 24.14  ? 193 ARG F N   1 
ATOM   19252 C CA  . ARG F 1 193 ? 22.432  75.343  32.912  1.00 21.97  ? 193 ARG F CA  1 
ATOM   19253 C C   . ARG F 1 193 ? 23.905  75.712  32.829  1.00 21.86  ? 193 ARG F C   1 
ATOM   19254 O O   . ARG F 1 193 ? 24.744  74.880  33.169  1.00 21.86  ? 193 ARG F O   1 
ATOM   19255 C CB  . ARG F 1 193 ? 21.953  74.905  31.528  1.00 21.16  ? 193 ARG F CB  1 
ATOM   19256 C CG  . ARG F 1 193 ? 22.635  73.599  31.139  1.00 22.11  ? 193 ARG F CG  1 
ATOM   19257 C CD  . ARG F 1 193 ? 22.127  73.087  29.825  1.00 21.82  ? 193 ARG F CD  1 
ATOM   19258 N NE  . ARG F 1 193 ? 22.888  71.898  29.464  1.00 22.68  ? 193 ARG F NE  1 
ATOM   19259 C CZ  . ARG F 1 193 ? 23.405  71.698  28.264  1.00 23.15  ? 193 ARG F CZ  1 
ATOM   19260 N NH1 . ARG F 1 193 ? 23.137  72.540  27.269  1.00 22.58  ? 193 ARG F NH1 1 
ATOM   19261 N NH2 . ARG F 1 193 ? 24.184  70.644  28.064  1.00 25.81  ? 193 ARG F NH2 1 
ATOM   19262 N N   . LYS F 1 194 ? 24.214  76.900  32.283  1.00 21.09  ? 194 LYS F N   1 
ATOM   19263 C CA  . LYS F 1 194 ? 25.602  77.237  31.989  1.00 23.43  ? 194 LYS F CA  1 
ATOM   19264 C C   . LYS F 1 194 ? 26.320  77.703  33.253  1.00 25.22  ? 194 LYS F C   1 
ATOM   19265 O O   . LYS F 1 194 ? 27.441  77.285  33.516  1.00 25.60  ? 194 LYS F O   1 
ATOM   19266 C CB  . LYS F 1 194 ? 25.777  78.391  30.999  1.00 23.38  ? 194 LYS F CB  1 
ATOM   19267 C CG  . LYS F 1 194 ? 25.435  78.056  29.554  1.00 22.80  ? 194 LYS F CG  1 
ATOM   19268 C CD  . LYS F 1 194 ? 25.696  79.226  28.623  1.00 22.48  ? 194 LYS F CD  1 
ATOM   19269 C CE  . LYS F 1 194 ? 27.167  79.515  28.348  1.00 21.28  ? 194 LYS F CE  1 
ATOM   19270 N NZ  . LYS F 1 194 ? 27.736  78.463  27.509  1.00 22.09  ? 194 LYS F NZ  1 
ATOM   19271 N N   . TYR F 1 195 ? 25.653  78.545  34.043  1.00 24.69  ? 195 TYR F N   1 
ATOM   19272 C CA  . TYR F 1 195 ? 26.337  79.354  35.032  1.00 26.64  ? 195 TYR F CA  1 
ATOM   19273 C C   . TYR F 1 195 ? 25.930  79.066  36.478  1.00 25.63  ? 195 TYR F C   1 
ATOM   19274 O O   . TYR F 1 195 ? 26.646  79.494  37.388  1.00 24.36  ? 195 TYR F O   1 
ATOM   19275 C CB  . TYR F 1 195 ? 26.068  80.825  34.701  1.00 28.90  ? 195 TYR F CB  1 
ATOM   19276 C CG  . TYR F 1 195 ? 26.534  81.265  33.321  1.00 30.13  ? 195 TYR F CG  1 
ATOM   19277 C CD1 . TYR F 1 195 ? 27.828  81.033  32.862  1.00 29.54  ? 195 TYR F CD1 1 
ATOM   19278 C CD2 . TYR F 1 195 ? 25.642  81.867  32.448  1.00 29.91  ? 195 TYR F CD2 1 
ATOM   19279 C CE1 . TYR F 1 195 ? 28.222  81.458  31.599  1.00 30.56  ? 195 TYR F CE1 1 
ATOM   19280 C CE2 . TYR F 1 195 ? 26.024  82.275  31.179  1.00 31.12  ? 195 TYR F CE2 1 
ATOM   19281 C CZ  . TYR F 1 195 ? 27.319  82.088  30.749  1.00 30.65  ? 195 TYR F CZ  1 
ATOM   19282 O OH  . TYR F 1 195 ? 27.614  82.508  29.471  1.00 30.03  ? 195 TYR F OH  1 
ATOM   19283 N N   . LYS F 1 196 ? 24.797  78.392  36.714  1.00 26.28  ? 196 LYS F N   1 
ATOM   19284 C CA  . LYS F 1 196 ? 24.363  78.128  38.079  1.00 27.91  ? 196 LYS F CA  1 
ATOM   19285 C C   . LYS F 1 196 ? 24.066  76.651  38.324  1.00 25.68  ? 196 LYS F C   1 
ATOM   19286 O O   . LYS F 1 196 ? 23.038  76.325  38.887  1.00 26.58  ? 196 LYS F O   1 
ATOM   19287 C CB  . LYS F 1 196 ? 23.125  78.962  38.422  1.00 32.58  ? 196 LYS F CB  1 
ATOM   19288 C CG  . LYS F 1 196 ? 23.276  80.469  38.298  1.00 35.89  ? 196 LYS F CG  1 
ATOM   19289 C CD  . LYS F 1 196 ? 24.285  81.068  39.263  1.00 39.63  ? 196 LYS F CD  1 
ATOM   19290 C CE  . LYS F 1 196 ? 23.950  82.474  39.641  1.00 42.82  ? 196 LYS F CE  1 
ATOM   19291 N NZ  . LYS F 1 196 ? 25.160  83.146  40.111  1.00 46.43  ? 196 LYS F NZ  1 
ATOM   19292 N N   . GLY F 1 197 ? 24.959  75.754  37.914  1.00 25.92  ? 197 GLY F N   1 
ATOM   19293 C CA  . GLY F 1 197 ? 24.891  74.364  38.332  1.00 25.05  ? 197 GLY F CA  1 
ATOM   19294 C C   . GLY F 1 197 ? 23.694  73.562  37.799  1.00 25.29  ? 197 GLY F C   1 
ATOM   19295 O O   . GLY F 1 197 ? 23.406  72.480  38.324  1.00 23.40  ? 197 GLY F O   1 
ATOM   19296 N N   . ASP F 1 198 ? 23.015  74.027  36.743  1.00 26.94  ? 198 ASP F N   1 
ATOM   19297 C CA  . ASP F 1 198 ? 21.987  73.206  36.103  1.00 26.26  ? 198 ASP F CA  1 
ATOM   19298 C C   . ASP F 1 198 ? 20.912  72.799  37.123  1.00 29.50  ? 198 ASP F C   1 
ATOM   19299 O O   . ASP F 1 198 ? 20.461  71.634  37.160  1.00 27.80  ? 198 ASP F O   1 
ATOM   19300 C CB  . ASP F 1 198 ? 22.599  71.986  35.420  1.00 23.65  ? 198 ASP F CB  1 
ATOM   19301 C CG  . ASP F 1 198 ? 21.732  71.252  34.403  1.00 23.33  ? 198 ASP F CG  1 
ATOM   19302 O OD1 . ASP F 1 198 ? 20.725  71.843  33.976  1.00 21.47  ? 198 ASP F OD1 1 
ATOM   19303 O OD2 . ASP F 1 198 ? 22.068  70.088  34.040  1.00 22.34  ? 198 ASP F OD2 1 
ATOM   19304 N N   . THR F 1 199 ? 20.506  73.776  37.949  1.00 28.61  ? 199 THR F N   1 
ATOM   19305 C CA  . THR F 1 199 ? 19.268  73.688  38.712  1.00 30.35  ? 199 THR F CA  1 
ATOM   19306 C C   . THR F 1 199 ? 18.320  74.769  38.213  1.00 28.64  ? 199 THR F C   1 
ATOM   19307 O O   . THR F 1 199 ? 18.747  75.871  37.862  1.00 24.55  ? 199 THR F O   1 
ATOM   19308 C CB  . THR F 1 199 ? 19.478  73.849  40.223  1.00 29.83  ? 199 THR F CB  1 
ATOM   19309 O OG1 . THR F 1 199 ? 20.148  75.096  40.417  1.00 30.50  ? 199 THR F OG1 1 
ATOM   19310 C CG2 . THR F 1 199 ? 20.240  72.677  40.808  1.00 30.36  ? 199 THR F CG2 1 
ATOM   19311 N N   . HIS F 1 200 ? 17.027  74.449  38.277  1.00 30.45  ? 200 HIS F N   1 
ATOM   19312 C CA  . HIS F 1 200 ? 16.032  75.217  37.558  1.00 32.27  ? 200 HIS F CA  1 
ATOM   19313 C C   . HIS F 1 200 ? 14.931  75.657  38.507  1.00 34.66  ? 200 HIS F C   1 
ATOM   19314 O O   . HIS F 1 200 ? 14.425  74.867  39.293  1.00 35.80  ? 200 HIS F O   1 
ATOM   19315 C CB  . HIS F 1 200 ? 15.555  74.455  36.320  1.00 30.85  ? 200 HIS F CB  1 
ATOM   19316 C CG  . HIS F 1 200 ? 16.697  74.084  35.447  1.00 29.33  ? 200 HIS F CG  1 
ATOM   19317 N ND1 . HIS F 1 200 ? 17.209  74.954  34.516  1.00 29.23  ? 200 HIS F ND1 1 
ATOM   19318 C CD2 . HIS F 1 200 ? 17.476  72.991  35.418  1.00 29.93  ? 200 HIS F CD2 1 
ATOM   19319 C CE1 . HIS F 1 200 ? 18.243  74.377  33.913  1.00 28.90  ? 200 HIS F CE1 1 
ATOM   19320 N NE2 . HIS F 1 200 ? 18.429  73.190  34.455  1.00 27.85  ? 200 HIS F NE2 1 
ATOM   19321 N N   . ILE F 1 201 ? 14.612  76.948  38.389  1.00 36.59  ? 201 ILE F N   1 
ATOM   19322 C CA  . ILE F 1 201 ? 13.598  77.638  39.159  1.00 34.05  ? 201 ILE F CA  1 
ATOM   19323 C C   . ILE F 1 201 ? 12.432  77.892  38.207  1.00 31.96  ? 201 ILE F C   1 
ATOM   19324 O O   . ILE F 1 201 ? 12.620  78.483  37.139  1.00 29.37  ? 201 ILE F O   1 
ATOM   19325 C CB  . ILE F 1 201 ? 14.190  78.943  39.741  1.00 33.11  ? 201 ILE F CB  1 
ATOM   19326 C CG1 . ILE F 1 201 ? 15.391  78.684  40.634  1.00 35.06  ? 201 ILE F CG1 1 
ATOM   19327 C CG2 . ILE F 1 201 ? 13.144  79.783  40.467  1.00 32.22  ? 201 ILE F CG2 1 
ATOM   19328 C CD1 . ILE F 1 201 ? 16.284  79.901  40.824  1.00 36.27  ? 201 ILE F CD1 1 
ATOM   19329 N N   . ALA F 1 202 ? 11.245  77.445  38.637  1.00 32.97  ? 202 ALA F N   1 
ATOM   19330 C CA  . ALA F 1 202 ? 9.976   77.661  37.950  1.00 33.63  ? 202 ALA F CA  1 
ATOM   19331 C C   . ALA F 1 202 ? 9.553   79.130  38.002  1.00 29.38  ? 202 ALA F C   1 
ATOM   19332 O O   . ALA F 1 202 ? 9.946   79.888  38.876  1.00 30.14  ? 202 ALA F O   1 
ATOM   19333 C CB  . ALA F 1 202 ? 8.895   76.777  38.558  1.00 33.32  ? 202 ALA F CB  1 
ATOM   19334 N N   . PRO F 1 203 ? 8.728   79.580  37.043  1.00 30.24  ? 203 PRO F N   1 
ATOM   19335 C CA  . PRO F 1 203 ? 8.087   80.894  37.142  1.00 33.79  ? 203 PRO F CA  1 
ATOM   19336 C C   . PRO F 1 203 ? 7.272   81.041  38.425  1.00 33.28  ? 203 PRO F C   1 
ATOM   19337 O O   . PRO F 1 203 ? 6.700   80.069  38.928  1.00 29.97  ? 203 PRO F O   1 
ATOM   19338 C CB  . PRO F 1 203 ? 7.173   80.987  35.905  1.00 31.48  ? 203 PRO F CB  1 
ATOM   19339 C CG  . PRO F 1 203 ? 7.669   79.902  34.967  1.00 29.60  ? 203 PRO F CG  1 
ATOM   19340 C CD  . PRO F 1 203 ? 8.362   78.851  35.819  1.00 29.25  ? 203 PRO F CD  1 
ATOM   19341 N N   . ASP F 1 204 ? 7.258   82.279  38.925  1.00 33.57  ? 204 ASP F N   1 
ATOM   19342 C CA  . ASP F 1 204 ? 6.403   82.707  40.014  1.00 34.88  ? 204 ASP F CA  1 
ATOM   19343 C C   . ASP F 1 204 ? 5.226   83.457  39.394  1.00 34.43  ? 204 ASP F C   1 
ATOM   19344 O O   . ASP F 1 204 ? 5.392   84.554  38.865  1.00 33.45  ? 204 ASP F O   1 
ATOM   19345 C CB  . ASP F 1 204 ? 7.188   83.569  40.998  1.00 36.62  ? 204 ASP F CB  1 
ATOM   19346 C CG  . ASP F 1 204 ? 6.390   84.251  42.107  1.00 38.16  ? 204 ASP F CG  1 
ATOM   19347 O OD1 . ASP F 1 204 ? 5.161   84.086  42.144  1.00 37.98  ? 204 ASP F OD1 1 
ATOM   19348 O OD2 . ASP F 1 204 ? 7.002   84.965  42.929  1.00 39.50  ? 204 ASP F OD2 1 
ATOM   19349 N N   . PRO F 1 205 ? 3.982   82.956  39.519  1.00 35.44  ? 205 PRO F N   1 
ATOM   19350 C CA  . PRO F 1 205 ? 2.843   83.615  38.876  1.00 37.29  ? 205 PRO F CA  1 
ATOM   19351 C C   . PRO F 1 205 ? 2.471   84.998  39.427  1.00 39.22  ? 205 PRO F C   1 
ATOM   19352 O O   . PRO F 1 205 ? 1.693   85.706  38.806  1.00 39.25  ? 205 PRO F O   1 
ATOM   19353 C CB  . PRO F 1 205 ? 1.710   82.597  39.031  1.00 34.97  ? 205 PRO F CB  1 
ATOM   19354 C CG  . PRO F 1 205 ? 2.086   81.806  40.272  1.00 36.60  ? 205 PRO F CG  1 
ATOM   19355 C CD  . PRO F 1 205 ? 3.603   81.796  40.339  1.00 36.29  ? 205 PRO F CD  1 
ATOM   19356 N N   . ASN F 1 206 ? 3.045   85.409  40.562  1.00 38.21  ? 206 ASN F N   1 
ATOM   19357 C CA  . ASN F 1 206 ? 2.763   86.715  41.129  1.00 40.32  ? 206 ASN F CA  1 
ATOM   19358 C C   . ASN F 1 206 ? 3.721   87.801  40.639  1.00 40.89  ? 206 ASN F C   1 
ATOM   19359 O O   . ASN F 1 206 ? 3.628   88.945  41.097  1.00 44.67  ? 206 ASN F O   1 
ATOM   19360 C CB  . ASN F 1 206 ? 2.879   86.687  42.650  1.00 50.05  ? 206 ASN F CB  1 
ATOM   19361 C CG  . ASN F 1 206 ? 1.775   85.873  43.272  1.00 57.05  ? 206 ASN F CG  1 
ATOM   19362 O OD1 . ASN F 1 206 ? 0.639   85.879  42.785  1.00 66.82  ? 206 ASN F OD1 1 
ATOM   19363 N ND2 . ASN F 1 206 ? 2.090   85.161  44.337  1.00 61.41  ? 206 ASN F ND2 1 
ATOM   19364 N N   . LEU F 1 207 ? 4.673   87.451  39.765  1.00 36.56  ? 207 LEU F N   1 
ATOM   19365 C CA  . LEU F 1 207 ? 5.653   88.426  39.315  1.00 33.96  ? 207 LEU F CA  1 
ATOM   19366 C C   . LEU F 1 207 ? 5.284   88.929  37.923  1.00 27.77  ? 207 LEU F C   1 
ATOM   19367 O O   . LEU F 1 207 ? 4.766   88.181  37.129  1.00 26.31  ? 207 LEU F O   1 
ATOM   19368 C CB  . LEU F 1 207 ? 7.073   87.848  39.345  1.00 32.29  ? 207 LEU F CB  1 
ATOM   19369 C CG  . LEU F 1 207 ? 7.634   87.485  40.722  1.00 28.70  ? 207 LEU F CG  1 
ATOM   19370 C CD1 . LEU F 1 207 ? 9.016   86.860  40.621  1.00 27.90  ? 207 LEU F CD1 1 
ATOM   19371 C CD2 . LEU F 1 207 ? 7.666   88.724  41.588  1.00 29.47  ? 207 LEU F CD2 1 
ATOM   19372 N N   . ASP F 1 208 ? 5.579   90.202  37.641  1.00 28.27  ? 208 ASP F N   1 
ATOM   19373 C CA  . ASP F 1 208 ? 5.638   90.701  36.278  1.00 27.82  ? 208 ASP F CA  1 
ATOM   19374 C C   . ASP F 1 208 ? 6.774   90.018  35.505  1.00 28.19  ? 208 ASP F C   1 
ATOM   19375 O O   . ASP F 1 208 ? 7.609   89.312  36.067  1.00 30.76  ? 208 ASP F O   1 
ATOM   19376 C CB  . ASP F 1 208 ? 5.815   92.209  36.285  1.00 28.86  ? 208 ASP F CB  1 
ATOM   19377 C CG  . ASP F 1 208 ? 7.023   92.698  37.060  1.00 33.34  ? 208 ASP F CG  1 
ATOM   19378 O OD1 . ASP F 1 208 ? 7.008   92.464  38.282  1.00 38.48  ? 208 ASP F OD1 1 
ATOM   19379 O OD2 . ASP F 1 208 ? 7.958   93.299  36.442  1.00 35.13  ? 208 ASP F OD2 1 
ATOM   19380 N N   . TRP F 1 209 ? 6.816   90.286  34.201  1.00 26.75  ? 209 TRP F N   1 
ATOM   19381 C CA  . TRP F 1 209 ? 7.627   89.572  33.229  1.00 26.19  ? 209 TRP F CA  1 
ATOM   19382 C C   . TRP F 1 209 ? 9.128   89.701  33.521  1.00 26.55  ? 209 TRP F C   1 
ATOM   19383 O O   . TRP F 1 209 ? 9.842   88.696  33.529  1.00 23.61  ? 209 TRP F O   1 
ATOM   19384 C CB  . TRP F 1 209 ? 7.238   90.155  31.860  1.00 26.02  ? 209 TRP F CB  1 
ATOM   19385 C CG  . TRP F 1 209 ? 7.784   89.498  30.614  1.00 25.36  ? 209 TRP F CG  1 
ATOM   19386 C CD1 . TRP F 1 209 ? 7.502   88.261  30.097  1.00 24.61  ? 209 TRP F CD1 1 
ATOM   19387 C CD2 . TRP F 1 209 ? 8.642   90.144  29.658  1.00 22.96  ? 209 TRP F CD2 1 
ATOM   19388 N NE1 . TRP F 1 209 ? 8.137   88.092  28.901  1.00 22.90  ? 209 TRP F NE1 1 
ATOM   19389 C CE2 . TRP F 1 209 ? 8.858   89.218  28.615  1.00 24.03  ? 209 TRP F CE2 1 
ATOM   19390 C CE3 . TRP F 1 209 ? 9.276   91.391  29.617  1.00 23.28  ? 209 TRP F CE3 1 
ATOM   19391 C CZ2 . TRP F 1 209 ? 9.684   89.510  27.527  1.00 26.33  ? 209 TRP F CZ2 1 
ATOM   19392 C CZ3 . TRP F 1 209 ? 10.088  91.684  28.544  1.00 24.77  ? 209 TRP F CZ3 1 
ATOM   19393 C CH2 . TRP F 1 209 ? 10.274  90.760  27.501  1.00 26.68  ? 209 TRP F CH2 1 
ATOM   19394 N N   . SER F 1 210 ? 9.601   90.939  33.724  1.00 26.00  ? 210 SER F N   1 
ATOM   19395 C CA  . SER F 1 210 ? 11.018  91.228  33.919  1.00 29.07  ? 210 SER F CA  1 
ATOM   19396 C C   . SER F 1 210 ? 11.534  90.591  35.211  1.00 28.59  ? 210 SER F C   1 
ATOM   19397 O O   . SER F 1 210 ? 12.630  90.033  35.259  1.00 26.81  ? 210 SER F O   1 
ATOM   19398 C CB  . SER F 1 210 ? 11.263  92.731  33.955  1.00 32.89  ? 210 SER F CB  1 
ATOM   19399 O OG  . SER F 1 210 ? 10.328  93.416  33.135  1.00 39.63  ? 210 SER F OG  1 
ATOM   19400 N N   . ALA F 1 211 ? 10.720  90.713  36.266  1.00 28.98  ? 211 ALA F N   1 
ATOM   19401 C CA  . ALA F 1 211 ? 11.083  90.268  37.591  1.00 26.71  ? 211 ALA F CA  1 
ATOM   19402 C C   . ALA F 1 211 ? 11.190  88.762  37.595  1.00 27.09  ? 211 ALA F C   1 
ATOM   19403 O O   . ALA F 1 211 ? 12.033  88.207  38.272  1.00 29.26  ? 211 ALA F O   1 
ATOM   19404 C CB  . ALA F 1 211 ? 10.040  90.714  38.566  1.00 29.48  ? 211 ALA F CB  1 
ATOM   19405 N N   . ASN F 1 212 ? 10.290  88.137  36.849  1.00 28.36  ? 212 ASN F N   1 
ATOM   19406 C CA  . ASN F 1 212 ? 10.220  86.694  36.772  1.00 30.92  ? 212 ASN F CA  1 
ATOM   19407 C C   . ASN F 1 212 ? 11.482  86.158  36.107  1.00 29.95  ? 212 ASN F C   1 
ATOM   19408 O O   . ASN F 1 212 ? 11.872  85.041  36.375  1.00 30.18  ? 212 ASN F O   1 
ATOM   19409 C CB  . ASN F 1 212 ? 9.012   86.240  35.957  1.00 32.51  ? 212 ASN F CB  1 
ATOM   19410 C CG  . ASN F 1 212 ? 8.204   85.203  36.689  1.00 36.00  ? 212 ASN F CG  1 
ATOM   19411 O OD1 . ASN F 1 212 ? 8.751   84.403  37.457  1.00 33.72  ? 212 ASN F OD1 1 
ATOM   19412 N ND2 . ASN F 1 212 ? 6.893   85.242  36.504  1.00 41.53  ? 212 ASN F ND2 1 
ATOM   19413 N N   . LEU F 1 213 ? 12.063  86.933  35.183  1.00 29.15  ? 213 LEU F N   1 
ATOM   19414 C CA  . LEU F 1 213 ? 13.302  86.543  34.543  1.00 29.12  ? 213 LEU F CA  1 
ATOM   19415 C C   . LEU F 1 213 ? 14.425  86.535  35.587  1.00 28.19  ? 213 LEU F C   1 
ATOM   19416 O O   . LEU F 1 213 ? 15.115  85.532  35.766  1.00 28.51  ? 213 LEU F O   1 
ATOM   19417 C CB  . LEU F 1 213 ? 13.583  87.467  33.359  1.00 31.21  ? 213 LEU F CB  1 
ATOM   19418 C CG  . LEU F 1 213 ? 14.919  87.250  32.632  1.00 32.75  ? 213 LEU F CG  1 
ATOM   19419 C CD1 . LEU F 1 213 ? 15.180  85.808  32.207  1.00 32.65  ? 213 LEU F CD1 1 
ATOM   19420 C CD2 . LEU F 1 213 ? 14.977  88.178  31.442  1.00 31.10  ? 213 LEU F CD2 1 
ATOM   19421 N N   . ALA F 1 214 ? 14.585  87.639  36.318  1.00 26.31  ? 214 ALA F N   1 
ATOM   19422 C CA  . ALA F 1 214 ? 15.520  87.647  37.432  1.00 23.99  ? 214 ALA F CA  1 
ATOM   19423 C C   . ALA F 1 214 ? 15.242  86.445  38.322  1.00 25.58  ? 214 ALA F C   1 
ATOM   19424 O O   . ALA F 1 214 ? 16.155  85.689  38.649  1.00 29.91  ? 214 ALA F O   1 
ATOM   19425 C CB  . ALA F 1 214 ? 15.430  88.940  38.209  1.00 22.52  ? 214 ALA F CB  1 
ATOM   19426 N N   . HIS F 1 215 ? 13.975  86.268  38.698  1.00 25.53  ? 215 HIS F N   1 
ATOM   19427 C CA  . HIS F 1 215 ? 13.603  85.242  39.653  1.00 26.33  ? 215 HIS F CA  1 
ATOM   19428 C C   . HIS F 1 215 ? 14.164  83.907  39.188  1.00 25.44  ? 215 HIS F C   1 
ATOM   19429 O O   . HIS F 1 215 ? 14.792  83.204  39.975  1.00 26.10  ? 215 HIS F O   1 
ATOM   19430 C CB  . HIS F 1 215 ? 12.080  85.138  39.857  1.00 26.95  ? 215 HIS F CB  1 
ATOM   19431 C CG  . HIS F 1 215 ? 11.707  84.048  40.796  1.00 29.19  ? 215 HIS F CG  1 
ATOM   19432 N ND1 . HIS F 1 215 ? 12.104  84.029  42.129  1.00 30.49  ? 215 HIS F ND1 1 
ATOM   19433 C CD2 . HIS F 1 215 ? 11.041  82.903  40.576  1.00 30.80  ? 215 HIS F CD2 1 
ATOM   19434 C CE1 . HIS F 1 215 ? 11.633  82.918  42.694  1.00 33.43  ? 215 HIS F CE1 1 
ATOM   19435 N NE2 . HIS F 1 215 ? 10.963  82.224  41.775  1.00 31.64  ? 215 HIS F NE2 1 
ATOM   19436 N N   . MET F 1 216 ? 13.951  83.602  37.903  1.00 26.84  ? 216 MET F N   1 
ATOM   19437 C CA  . MET F 1 216 ? 14.254  82.303  37.316  1.00 27.85  ? 216 MET F CA  1 
ATOM   19438 C C   . MET F 1 216 ? 15.763  82.163  37.071  1.00 28.19  ? 216 MET F C   1 
ATOM   19439 O O   . MET F 1 216 ? 16.273  81.045  37.018  1.00 25.98  ? 216 MET F O   1 
ATOM   19440 C CB  . MET F 1 216 ? 13.489  82.127  36.001  1.00 29.54  ? 216 MET F CB  1 
ATOM   19441 C CG  . MET F 1 216 ? 12.029  81.839  36.185  1.00 30.91  ? 216 MET F CG  1 
ATOM   19442 S SD  . MET F 1 216 ? 11.134  81.375  34.686  1.00 30.62  ? 216 MET F SD  1 
ATOM   19443 C CE  . MET F 1 216 ? 11.308  82.916  33.768  1.00 31.21  ? 216 MET F CE  1 
ATOM   19444 N N   . MET F 1 217 ? 16.472  83.302  36.947  1.00 29.69  ? 217 MET F N   1 
ATOM   19445 C CA  . MET F 1 217 ? 17.936  83.341  36.942  1.00 30.42  ? 217 MET F CA  1 
ATOM   19446 C C   . MET F 1 217 ? 18.511  83.095  38.344  1.00 32.95  ? 217 MET F C   1 
ATOM   19447 O O   . MET F 1 217 ? 19.617  82.568  38.473  1.00 34.91  ? 217 MET F O   1 
ATOM   19448 C CB  . MET F 1 217 ? 18.446  84.673  36.379  1.00 25.72  ? 217 MET F CB  1 
ATOM   19449 C CG  . MET F 1 217 ? 18.339  84.721  34.878  1.00 26.35  ? 217 MET F CG  1 
ATOM   19450 S SD  . MET F 1 217 ? 18.597  86.392  34.261  1.00 27.45  ? 217 MET F SD  1 
ATOM   19451 C CE  . MET F 1 217 ? 20.326  86.624  34.694  1.00 26.70  ? 217 MET F CE  1 
ATOM   19452 N N   . GLY F 1 218 ? 17.764  83.475  39.389  1.00 33.26  ? 218 GLY F N   1 
ATOM   19453 C CA  . GLY F 1 218 ? 18.177  83.246  40.770  1.00 33.66  ? 218 GLY F CA  1 
ATOM   19454 C C   . GLY F 1 218 ? 18.322  84.536  41.588  1.00 29.86  ? 218 GLY F C   1 
ATOM   19455 O O   . GLY F 1 218 ? 18.968  84.506  42.613  1.00 32.24  ? 218 GLY F O   1 
ATOM   19456 N N   . PHE F 1 219 ? 17.755  85.670  41.145  1.00 30.56  ? 219 PHE F N   1 
ATOM   19457 C CA  . PHE F 1 219 ? 17.963  86.960  41.807  1.00 31.26  ? 219 PHE F CA  1 
ATOM   19458 C C   . PHE F 1 219 ? 16.623  87.600  42.167  1.00 33.62  ? 219 PHE F C   1 
ATOM   19459 O O   . PHE F 1 219 ? 15.801  87.830  41.278  1.00 28.80  ? 219 PHE F O   1 
ATOM   19460 C CB  . PHE F 1 219 ? 18.724  87.945  40.924  1.00 29.39  ? 219 PHE F CB  1 
ATOM   19461 C CG  . PHE F 1 219 ? 20.069  87.368  40.529  1.00 30.94  ? 219 PHE F CG  1 
ATOM   19462 C CD1 . PHE F 1 219 ? 20.188  86.508  39.445  1.00 31.57  ? 219 PHE F CD1 1 
ATOM   19463 C CD2 . PHE F 1 219 ? 21.208  87.673  41.250  1.00 30.82  ? 219 PHE F CD2 1 
ATOM   19464 C CE1 . PHE F 1 219 ? 21.416  85.967  39.112  1.00 34.10  ? 219 PHE F CE1 1 
ATOM   19465 C CE2 . PHE F 1 219 ? 22.440  87.139  40.898  1.00 32.15  ? 219 PHE F CE2 1 
ATOM   19466 C CZ  . PHE F 1 219 ? 22.549  86.284  39.844  1.00 31.27  ? 219 PHE F CZ  1 
ATOM   19467 N N   . ASP F 1 220 ? 16.401  87.863  43.472  1.00 32.98  ? 220 ASP F N   1 
ATOM   19468 C CA  . ASP F 1 220 ? 15.071  88.221  43.938  1.00 32.40  ? 220 ASP F CA  1 
ATOM   19469 C C   . ASP F 1 220 ? 15.078  89.555  44.683  1.00 32.56  ? 220 ASP F C   1 
ATOM   19470 O O   . ASP F 1 220 ? 14.028  89.929  45.193  1.00 29.35  ? 220 ASP F O   1 
ATOM   19471 C CB  . ASP F 1 220 ? 14.417  87.097  44.726  1.00 30.11  ? 220 ASP F CB  1 
ATOM   19472 C CG  . ASP F 1 220 ? 13.980  85.886  43.921  1.00 30.54  ? 220 ASP F CG  1 
ATOM   19473 O OD1 . ASP F 1 220 ? 13.168  86.049  42.990  1.00 37.16  ? 220 ASP F OD1 1 
ATOM   19474 O OD2 . ASP F 1 220 ? 14.428  84.782  44.246  1.00 26.75  ? 220 ASP F OD2 1 
ATOM   19475 N N   . ASP F 1 221 ? 16.201  90.300  44.698  1.00 33.86  ? 221 ASP F N   1 
ATOM   19476 C CA  . ASP F 1 221 ? 16.171  91.625  45.307  1.00 38.20  ? 221 ASP F CA  1 
ATOM   19477 C C   . ASP F 1 221 ? 15.319  92.557  44.460  1.00 35.90  ? 221 ASP F C   1 
ATOM   19478 O O   . ASP F 1 221 ? 15.437  92.583  43.236  1.00 30.17  ? 221 ASP F O   1 
ATOM   19479 C CB  . ASP F 1 221 ? 17.509  92.343  45.455  1.00 43.29  ? 221 ASP F CB  1 
ATOM   19480 C CG  . ASP F 1 221 ? 18.458  91.837  46.528  1.00 52.26  ? 221 ASP F CG  1 
ATOM   19481 O OD1 . ASP F 1 221 ? 18.142  90.811  47.190  1.00 54.94  ? 221 ASP F OD1 1 
ATOM   19482 O OD2 . ASP F 1 221 ? 19.523  92.462  46.668  1.00 59.99  ? 221 ASP F OD2 1 
ATOM   19483 N N   . PHE F 1 222 ? 14.520  93.362  45.169  1.00 37.54  ? 222 PHE F N   1 
ATOM   19484 C CA  . PHE F 1 222 ? 13.727  94.431  44.594  1.00 35.97  ? 222 PHE F CA  1 
ATOM   19485 C C   . PHE F 1 222 ? 14.537  95.267  43.613  1.00 34.41  ? 222 PHE F C   1 
ATOM   19486 O O   . PHE F 1 222 ? 14.066  95.528  42.513  1.00 37.95  ? 222 PHE F O   1 
ATOM   19487 C CB  . PHE F 1 222 ? 13.272  95.351  45.718  1.00 34.39  ? 222 PHE F CB  1 
ATOM   19488 C CG  . PHE F 1 222 ? 12.498  96.582  45.263  1.00 34.53  ? 222 PHE F CG  1 
ATOM   19489 C CD1 . PHE F 1 222 ? 11.170  96.471  44.858  1.00 28.72  ? 222 PHE F CD1 1 
ATOM   19490 C CD2 . PHE F 1 222 ? 13.091  97.857  45.308  1.00 36.09  ? 222 PHE F CD2 1 
ATOM   19491 C CE1 . PHE F 1 222 ? 10.462  97.602  44.494  1.00 29.31  ? 222 PHE F CE1 1 
ATOM   19492 C CE2 . PHE F 1 222 ? 12.383  98.992  44.915  1.00 32.24  ? 222 PHE F CE2 1 
ATOM   19493 C CZ  . PHE F 1 222 ? 11.068  98.856  44.512  1.00 32.47  ? 222 PHE F CZ  1 
ATOM   19494 N N   . GLU F 1 223 ? 15.727  95.701  44.029  1.00 31.29  ? 223 GLU F N   1 
ATOM   19495 C CA  . GLU F 1 223 ? 16.563  96.522  43.177  1.00 34.35  ? 223 GLU F CA  1 
ATOM   19496 C C   . GLU F 1 223 ? 16.909  95.755  41.897  1.00 34.85  ? 223 GLU F C   1 
ATOM   19497 O O   . GLU F 1 223 ? 16.977  96.345  40.821  1.00 30.68  ? 223 GLU F O   1 
ATOM   19498 C CB  . GLU F 1 223 ? 17.833  96.986  43.888  1.00 38.77  ? 223 GLU F CB  1 
ATOM   19499 C CG  . GLU F 1 223 ? 17.604  98.019  44.992  1.00 43.84  ? 223 GLU F CG  1 
ATOM   19500 C CD  . GLU F 1 223 ? 18.883  98.578  45.619  1.00 51.63  ? 223 GLU F CD  1 
ATOM   19501 O OE1 . GLU F 1 223 ? 18.804  99.182  46.719  1.00 54.32  ? 223 GLU F OE1 1 
ATOM   19502 O OE2 . GLU F 1 223 ? 19.972  98.421  44.996  1.00 54.70  ? 223 GLU F OE2 1 
ATOM   19503 N N   . VAL F 1 224 ? 17.094  94.433  41.994  1.00 31.32  ? 224 VAL F N   1 
ATOM   19504 C CA  . VAL F 1 224 ? 17.370  93.658  40.801  1.00 29.96  ? 224 VAL F CA  1 
ATOM   19505 C C   . VAL F 1 224 ? 16.123  93.653  39.919  1.00 32.40  ? 224 VAL F C   1 
ATOM   19506 O O   . VAL F 1 224 ? 16.228  93.831  38.700  1.00 34.45  ? 224 VAL F O   1 
ATOM   19507 C CB  . VAL F 1 224 ? 17.853  92.234  41.107  1.00 32.96  ? 224 VAL F CB  1 
ATOM   19508 C CG1 . VAL F 1 224 ? 18.113  91.439  39.826  1.00 38.36  ? 224 VAL F CG1 1 
ATOM   19509 C CG2 . VAL F 1 224 ? 19.114  92.254  41.962  1.00 33.15  ? 224 VAL F CG2 1 
ATOM   19510 N N   . TYR F 1 225 ? 14.945  93.459  40.530  1.00 30.30  ? 225 TYR F N   1 
ATOM   19511 C CA  . TYR F 1 225 ? 13.716  93.471  39.765  1.00 30.24  ? 225 TYR F CA  1 
ATOM   19512 C C   . TYR F 1 225 ? 13.589  94.842  39.082  1.00 30.63  ? 225 TYR F C   1 
ATOM   19513 O O   . TYR F 1 225 ? 13.283  94.945  37.893  1.00 29.66  ? 225 TYR F O   1 
ATOM   19514 C CB  . TYR F 1 225 ? 12.496  93.148  40.630  1.00 29.83  ? 225 TYR F CB  1 
ATOM   19515 C CG  . TYR F 1 225 ? 12.318  91.739  41.187  1.00 28.79  ? 225 TYR F CG  1 
ATOM   19516 C CD1 . TYR F 1 225 ? 13.021  90.651  40.711  1.00 27.87  ? 225 TYR F CD1 1 
ATOM   19517 C CD2 . TYR F 1 225 ? 11.383  91.501  42.190  1.00 27.24  ? 225 TYR F CD2 1 
ATOM   19518 C CE1 . TYR F 1 225 ? 12.815  89.379  41.237  1.00 30.33  ? 225 TYR F CE1 1 
ATOM   19519 C CE2 . TYR F 1 225 ? 11.158  90.243  42.712  1.00 26.49  ? 225 TYR F CE2 1 
ATOM   19520 C CZ  . TYR F 1 225 ? 11.887  89.165  42.246  1.00 28.05  ? 225 TYR F CZ  1 
ATOM   19521 O OH  . TYR F 1 225 ? 11.666  87.904  42.765  1.00 23.61  ? 225 TYR F OH  1 
ATOM   19522 N N   . GLU F 1 226 ? 13.862  95.914  39.821  1.00 28.68  ? 226 GLU F N   1 
ATOM   19523 C CA  . GLU F 1 226 ? 13.849  97.239  39.229  1.00 31.06  ? 226 GLU F CA  1 
ATOM   19524 C C   . GLU F 1 226 ? 14.837  97.381  38.065  1.00 32.27  ? 226 GLU F C   1 
ATOM   19525 O O   . GLU F 1 226 ? 14.489  98.023  37.084  1.00 31.08  ? 226 GLU F O   1 
ATOM   19526 C CB  . GLU F 1 226 ? 14.066  98.319  40.276  1.00 30.28  ? 226 GLU F CB  1 
ATOM   19527 C CG  . GLU F 1 226 ? 12.859  98.418  41.198  1.00 31.55  ? 226 GLU F CG  1 
ATOM   19528 C CD  . GLU F 1 226 ? 11.625  99.086  40.633  1.00 28.48  ? 226 GLU F CD  1 
ATOM   19529 O OE1 . GLU F 1 226 ? 10.632  98.398  40.302  1.00 26.26  ? 226 GLU F OE1 1 
ATOM   19530 O OE2 . GLU F 1 226 ? 11.674  100.326 40.601  1.00 28.65  ? 226 GLU F OE2 1 
ATOM   19531 N N   . LEU F 1 227 ? 16.051  96.817  38.187  1.00 32.79  ? 227 LEU F N   1 
ATOM   19532 C CA  . LEU F 1 227 ? 17.052  96.899  37.134  1.00 31.93  ? 227 LEU F CA  1 
ATOM   19533 C C   . LEU F 1 227 ? 16.526  96.218  35.863  1.00 28.85  ? 227 LEU F C   1 
ATOM   19534 O O   . LEU F 1 227 ? 16.588  96.791  34.788  1.00 24.48  ? 227 LEU F O   1 
ATOM   19535 C CB  . LEU F 1 227 ? 18.388  96.306  37.592  1.00 31.64  ? 227 LEU F CB  1 
ATOM   19536 C CG  . LEU F 1 227 ? 19.452  96.149  36.493  1.00 31.28  ? 227 LEU F CG  1 
ATOM   19537 C CD1 . LEU F 1 227 ? 19.699  97.501  35.836  1.00 30.89  ? 227 LEU F CD1 1 
ATOM   19538 C CD2 . LEU F 1 227 ? 20.742  95.538  37.022  1.00 29.69  ? 227 LEU F CD2 1 
ATOM   19539 N N   . PHE F 1 228 ? 15.952  95.019  36.012  1.00 27.47  ? 228 PHE F N   1 
ATOM   19540 C CA  . PHE F 1 228 ? 15.426  94.257  34.892  1.00 25.88  ? 228 PHE F CA  1 
ATOM   19541 C C   . PHE F 1 228 ? 14.272  94.978  34.196  1.00 26.58  ? 228 PHE F C   1 
ATOM   19542 O O   . PHE F 1 228 ? 14.170  94.935  32.963  1.00 26.51  ? 228 PHE F O   1 
ATOM   19543 C CB  . PHE F 1 228 ? 15.005  92.878  35.393  1.00 23.42  ? 228 PHE F CB  1 
ATOM   19544 C CG  . PHE F 1 228 ? 16.176  91.920  35.443  1.00 22.35  ? 228 PHE F CG  1 
ATOM   19545 C CD1 . PHE F 1 228 ? 17.394  92.311  35.968  1.00 23.49  ? 228 PHE F CD1 1 
ATOM   19546 C CD2 . PHE F 1 228 ? 16.080  90.659  34.878  1.00 25.42  ? 228 PHE F CD2 1 
ATOM   19547 C CE1 . PHE F 1 228 ? 18.478  91.440  35.987  1.00 24.96  ? 228 PHE F CE1 1 
ATOM   19548 C CE2 . PHE F 1 228 ? 17.171  89.790  34.897  1.00 27.38  ? 228 PHE F CE2 1 
ATOM   19549 C CZ  . PHE F 1 228 ? 18.364  90.179  35.476  1.00 25.17  ? 228 PHE F CZ  1 
ATOM   19550 N N   . ARG F 1 229 ? 13.416  95.636  34.985  1.00 27.97  ? 229 ARG F N   1 
ATOM   19551 C CA  . ARG F 1 229 ? 12.303  96.391  34.441  1.00 29.51  ? 229 ARG F CA  1 
ATOM   19552 C C   . ARG F 1 229 ? 12.827  97.514  33.556  1.00 29.13  ? 229 ARG F C   1 
ATOM   19553 O O   . ARG F 1 229 ? 12.408  97.636  32.403  1.00 26.63  ? 229 ARG F O   1 
ATOM   19554 C CB  . ARG F 1 229 ? 11.444  96.962  35.567  1.00 32.16  ? 229 ARG F CB  1 
ATOM   19555 C CG  . ARG F 1 229 ? 10.593  95.889  36.222  1.00 34.00  ? 229 ARG F CG  1 
ATOM   19556 C CD  . ARG F 1 229 ? 10.117  96.347  37.604  1.00 33.67  ? 229 ARG F CD  1 
ATOM   19557 N NE  . ARG F 1 229 ? 9.445   95.234  38.283  1.00 33.60  ? 229 ARG F NE  1 
ATOM   19558 C CZ  . ARG F 1 229 ? 9.575   94.937  39.567  1.00 33.23  ? 229 ARG F CZ  1 
ATOM   19559 N NH1 . ARG F 1 229 ? 10.299  95.688  40.379  1.00 33.17  ? 229 ARG F NH1 1 
ATOM   19560 N NH2 . ARG F 1 229 ? 8.946   93.893  40.040  1.00 32.81  ? 229 ARG F NH2 1 
ATOM   19561 N N   . LEU F 1 230 ? 13.780  98.291  34.092  1.00 27.78  ? 230 LEU F N   1 
ATOM   19562 C CA  . LEU F 1 230 ? 14.380  99.374  33.341  1.00 29.58  ? 230 LEU F CA  1 
ATOM   19563 C C   . LEU F 1 230 ? 15.100  98.820  32.104  1.00 30.26  ? 230 LEU F C   1 
ATOM   19564 O O   . LEU F 1 230 ? 15.021  99.407  31.014  1.00 30.81  ? 230 LEU F O   1 
ATOM   19565 C CB  . LEU F 1 230 ? 15.321  100.215 34.204  1.00 29.74  ? 230 LEU F CB  1 
ATOM   19566 C CG  . LEU F 1 230 ? 16.066  101.322 33.438  1.00 27.94  ? 230 LEU F CG  1 
ATOM   19567 C CD1 . LEU F 1 230 ? 15.052  102.312 32.910  1.00 28.11  ? 230 LEU F CD1 1 
ATOM   19568 C CD2 . LEU F 1 230 ? 17.117  102.014 34.256  1.00 26.79  ? 230 LEU F CD2 1 
ATOM   19569 N N   . TYR F 1 231 ? 15.813  97.703  32.278  1.00 26.98  ? 231 TYR F N   1 
ATOM   19570 C CA  . TYR F 1 231 ? 16.589  97.123  31.190  1.00 28.48  ? 231 TYR F CA  1 
ATOM   19571 C C   . TYR F 1 231 ? 15.674  96.675  30.052  1.00 30.21  ? 231 TYR F C   1 
ATOM   19572 O O   . TYR F 1 231 ? 15.945  96.959  28.883  1.00 29.02  ? 231 TYR F O   1 
ATOM   19573 C CB  . TYR F 1 231 ? 17.381  95.906  31.662  1.00 28.07  ? 231 TYR F CB  1 
ATOM   19574 C CG  . TYR F 1 231 ? 18.496  95.369  30.776  1.00 27.13  ? 231 TYR F CG  1 
ATOM   19575 C CD1 . TYR F 1 231 ? 18.211  94.644  29.632  1.00 29.17  ? 231 TYR F CD1 1 
ATOM   19576 C CD2 . TYR F 1 231 ? 19.831  95.510  31.139  1.00 27.61  ? 231 TYR F CD2 1 
ATOM   19577 C CE1 . TYR F 1 231 ? 19.219  94.117  28.842  1.00 28.97  ? 231 TYR F CE1 1 
ATOM   19578 C CE2 . TYR F 1 231 ? 20.852  94.984  30.368  1.00 29.20  ? 231 TYR F CE2 1 
ATOM   19579 C CZ  . TYR F 1 231 ? 20.541  94.287  29.209  1.00 30.16  ? 231 TYR F CZ  1 
ATOM   19580 O OH  . TYR F 1 231 ? 21.520  93.746  28.436  1.00 30.90  ? 231 TYR F OH  1 
ATOM   19581 N N   . MET F 1 232 ? 14.608  95.943  30.401  1.00 29.47  ? 232 MET F N   1 
ATOM   19582 C CA  . MET F 1 232 ? 13.703  95.444  29.380  1.00 27.02  ? 232 MET F CA  1 
ATOM   19583 C C   . MET F 1 232 ? 13.034  96.619  28.673  1.00 25.05  ? 232 MET F C   1 
ATOM   19584 O O   . MET F 1 232 ? 12.809  96.586  27.474  1.00 23.57  ? 232 MET F O   1 
ATOM   19585 C CB  . MET F 1 232 ? 12.641  94.528  29.981  1.00 26.03  ? 232 MET F CB  1 
ATOM   19586 C CG  . MET F 1 232 ? 13.162  93.248  30.572  1.00 27.76  ? 232 MET F CG  1 
ATOM   19587 S SD  . MET F 1 232 ? 13.912  92.130  29.382  1.00 29.35  ? 232 MET F SD  1 
ATOM   19588 C CE  . MET F 1 232 ? 15.650  92.306  29.800  1.00 29.52  ? 232 MET F CE  1 
ATOM   19589 N N   . PHE F 1 233 ? 12.708  97.662  29.428  1.00 25.71  ? 233 PHE F N   1 
ATOM   19590 C CA  . PHE F 1 233 ? 12.141  98.856  28.833  1.00 27.87  ? 233 PHE F CA  1 
ATOM   19591 C C   . PHE F 1 233 ? 13.111  99.529  27.861  1.00 27.74  ? 233 PHE F C   1 
ATOM   19592 O O   . PHE F 1 233 ? 12.708  99.864  26.755  1.00 29.01  ? 233 PHE F O   1 
ATOM   19593 C CB  . PHE F 1 233 ? 11.765  99.821  29.950  1.00 27.19  ? 233 PHE F CB  1 
ATOM   19594 C CG  . PHE F 1 233 ? 11.459  101.237 29.497  1.00 27.58  ? 233 PHE F CG  1 
ATOM   19595 C CD1 . PHE F 1 233 ? 10.156  101.625 29.208  1.00 28.44  ? 233 PHE F CD1 1 
ATOM   19596 C CD2 . PHE F 1 233 ? 12.454  102.204 29.479  1.00 28.38  ? 233 PHE F CD2 1 
ATOM   19597 C CE1 . PHE F 1 233 ? 9.853   102.938 28.887  1.00 27.74  ? 233 PHE F CE1 1 
ATOM   19598 C CE2 . PHE F 1 233 ? 12.150  103.517 29.141  1.00 29.48  ? 233 PHE F CE2 1 
ATOM   19599 C CZ  . PHE F 1 233 ? 10.850  103.879 28.847  1.00 28.82  ? 233 PHE F CZ  1 
ATOM   19600 N N   . LEU F 1 234 ? 14.365  99.748  28.289  1.00 28.58  ? 234 LEU F N   1 
ATOM   19601 C CA  . LEU F 1 234 ? 15.317  100.585 27.556  1.00 29.40  ? 234 LEU F CA  1 
ATOM   19602 C C   . LEU F 1 234 ? 15.743  99.926  26.239  1.00 30.42  ? 234 LEU F C   1 
ATOM   19603 O O   . LEU F 1 234 ? 16.003  100.634 25.254  1.00 34.11  ? 234 LEU F O   1 
ATOM   19604 C CB  . LEU F 1 234 ? 16.554  100.926 28.387  1.00 29.00  ? 234 LEU F CB  1 
ATOM   19605 C CG  . LEU F 1 234 ? 16.431  102.033 29.442  1.00 29.61  ? 234 LEU F CG  1 
ATOM   19606 C CD1 . LEU F 1 234 ? 17.795  102.168 30.087  1.00 30.58  ? 234 LEU F CD1 1 
ATOM   19607 C CD2 . LEU F 1 234 ? 15.997  103.415 28.944  1.00 30.79  ? 234 LEU F CD2 1 
ATOM   19608 N N   . HIS F 1 235 ? 15.811  98.584  26.210  1.00 27.52  ? 235 HIS F N   1 
ATOM   19609 C CA  . HIS F 1 235 ? 16.311  97.859  25.050  1.00 26.96  ? 235 HIS F CA  1 
ATOM   19610 C C   . HIS F 1 235 ? 15.176  97.352  24.145  1.00 27.43  ? 235 HIS F C   1 
ATOM   19611 O O   . HIS F 1 235 ? 15.412  96.570  23.219  1.00 30.28  ? 235 HIS F O   1 
ATOM   19612 C CB  . HIS F 1 235 ? 17.211  96.713  25.533  1.00 27.02  ? 235 HIS F CB  1 
ATOM   19613 C CG  . HIS F 1 235 ? 18.515  97.071  26.190  1.00 29.01  ? 235 HIS F CG  1 
ATOM   19614 N ND1 . HIS F 1 235 ? 18.636  97.368  27.534  1.00 29.53  ? 235 HIS F ND1 1 
ATOM   19615 C CD2 . HIS F 1 235 ? 19.778  97.066  25.697  1.00 29.88  ? 235 HIS F CD2 1 
ATOM   19616 C CE1 . HIS F 1 235 ? 19.926  97.541  27.821  1.00 31.96  ? 235 HIS F CE1 1 
ATOM   19617 N NE2 . HIS F 1 235 ? 20.641  97.359  26.722  1.00 29.91  ? 235 HIS F NE2 1 
ATOM   19618 N N   . SER F 1 236 ? 13.941  97.802  24.380  1.00 27.18  ? 236 SER F N   1 
ATOM   19619 C CA  . SER F 1 236 ? 12.758  97.268  23.707  1.00 29.90  ? 236 SER F CA  1 
ATOM   19620 C C   . SER F 1 236 ? 12.833  97.432  22.189  1.00 29.25  ? 236 SER F C   1 
ATOM   19621 O O   . SER F 1 236 ? 12.545  96.511  21.417  1.00 26.46  ? 236 SER F O   1 
ATOM   19622 C CB  . SER F 1 236 ? 11.509  97.942  24.210  1.00 29.36  ? 236 SER F CB  1 
ATOM   19623 O OG  . SER F 1 236 ? 11.669  99.355  24.137  1.00 30.41  ? 236 SER F OG  1 
ATOM   19624 N N   . ASP F 1 237 ? 13.189  98.638  21.762  1.00 29.51  ? 237 ASP F N   1 
ATOM   19625 C CA  . ASP F 1 237 ? 12.956  99.011  20.382  1.00 30.88  ? 237 ASP F CA  1 
ATOM   19626 C C   . ASP F 1 237 ? 13.846  100.203 20.057  1.00 28.55  ? 237 ASP F C   1 
ATOM   19627 O O   . ASP F 1 237 ? 14.176  100.954 20.967  1.00 25.73  ? 237 ASP F O   1 
ATOM   19628 C CB  . ASP F 1 237 ? 11.473  99.296  20.172  1.00 29.16  ? 237 ASP F CB  1 
ATOM   19629 C CG  . ASP F 1 237 ? 11.007  99.260  18.727  1.00 25.74  ? 237 ASP F CG  1 
ATOM   19630 O OD1 . ASP F 1 237 ? 11.308  98.261  18.059  1.00 26.74  ? 237 ASP F OD1 1 
ATOM   19631 O OD2 . ASP F 1 237 ? 10.372  100.232 18.284  1.00 23.52  ? 237 ASP F OD2 1 
ATOM   19632 N N   . HIS F 1 238 ? 14.201  100.362 18.770  1.00 26.77  ? 238 HIS F N   1 
ATOM   19633 C CA  . HIS F 1 238 ? 15.035  101.470 18.321  1.00 27.19  ? 238 HIS F CA  1 
ATOM   19634 C C   . HIS F 1 238 ? 14.880  101.615 16.802  1.00 27.48  ? 238 HIS F C   1 
ATOM   19635 O O   . HIS F 1 238 ? 15.841  101.373 16.073  1.00 27.87  ? 238 HIS F O   1 
ATOM   19636 C CB  . HIS F 1 238 ? 16.513  101.239 18.718  1.00 27.01  ? 238 HIS F CB  1 
ATOM   19637 C CG  . HIS F 1 238 ? 17.333  102.445 19.074  1.00 25.71  ? 238 HIS F CG  1 
ATOM   19638 N ND1 . HIS F 1 238 ? 18.564  102.716 18.520  1.00 25.87  ? 238 HIS F ND1 1 
ATOM   19639 C CD2 . HIS F 1 238 ? 17.102  103.441 19.942  1.00 26.88  ? 238 HIS F CD2 1 
ATOM   19640 C CE1 . HIS F 1 238 ? 19.063  103.829 19.055  1.00 25.82  ? 238 HIS F CE1 1 
ATOM   19641 N NE2 . HIS F 1 238 ? 18.185  104.291 19.916  1.00 27.71  ? 238 HIS F NE2 1 
ATOM   19642 N N   . GLU F 1 239 ? 13.692  102.047 16.329  1.00 28.96  ? 239 GLU F N   1 
ATOM   19643 C CA  . GLU F 1 239 ? 13.432  102.222 14.909  1.00 28.50  ? 239 GLU F CA  1 
ATOM   19644 C C   . GLU F 1 239 ? 13.410  100.862 14.204  1.00 29.60  ? 239 GLU F C   1 
ATOM   19645 O O   . GLU F 1 239 ? 13.575  99.800  14.824  1.00 21.92  ? 239 GLU F O   1 
ATOM   19646 C CB  . GLU F 1 239 ? 14.590  102.925 14.193  1.00 32.43  ? 239 GLU F CB  1 
ATOM   19647 C CG  . GLU F 1 239 ? 14.530  104.435 14.168  1.00 34.48  ? 239 GLU F CG  1 
ATOM   19648 C CD  . GLU F 1 239 ? 15.348  105.104 13.085  1.00 33.73  ? 239 GLU F CD  1 
ATOM   19649 O OE1 . GLU F 1 239 ? 15.309  106.347 13.161  1.00 40.63  ? 239 GLU F OE1 1 
ATOM   19650 O OE2 . GLU F 1 239 ? 15.958  104.485 12.179  1.00 31.59  ? 239 GLU F OE2 1 
ATOM   19651 N N   . GLY F 1 240 ? 13.305  100.942 12.864  1.00 29.76  ? 240 GLY F N   1 
ATOM   19652 C CA  . GLY F 1 240 ? 13.256  99.778  11.999  1.00 28.54  ? 240 GLY F CA  1 
ATOM   19653 C C   . GLY F 1 240 ? 14.632  99.337  11.530  1.00 27.33  ? 240 GLY F C   1 
ATOM   19654 O O   . GLY F 1 240 ? 14.807  98.147  11.257  1.00 27.30  ? 240 GLY F O   1 
ATOM   19655 N N   . GLY F 1 241 ? 15.591  100.284 11.499  1.00 27.43  ? 241 GLY F N   1 
ATOM   19656 C CA  . GLY F 1 241 ? 16.831  100.153 10.737  1.00 26.44  ? 241 GLY F CA  1 
ATOM   19657 C C   . GLY F 1 241 ? 17.987  99.399  11.416  1.00 25.02  ? 241 GLY F C   1 
ATOM   19658 O O   . GLY F 1 241 ? 19.001  99.116  10.766  1.00 24.73  ? 241 GLY F O   1 
ATOM   19659 N N   . ASN F 1 242 ? 17.885  99.100  12.715  1.00 23.08  ? 242 ASN F N   1 
ATOM   19660 C CA  . ASN F 1 242 ? 18.944  98.383  13.411  1.00 24.79  ? 242 ASN F CA  1 
ATOM   19661 C C   . ASN F 1 242 ? 18.960  96.939  12.905  1.00 25.16  ? 242 ASN F C   1 
ATOM   19662 O O   . ASN F 1 242 ? 17.946  96.454  12.428  1.00 23.00  ? 242 ASN F O   1 
ATOM   19663 C CB  . ASN F 1 242 ? 18.815  98.521  14.927  1.00 25.11  ? 242 ASN F CB  1 
ATOM   19664 C CG  . ASN F 1 242 ? 17.600  97.835  15.499  1.00 27.34  ? 242 ASN F CG  1 
ATOM   19665 O OD1 . ASN F 1 242 ? 17.538  96.598  15.562  1.00 27.00  ? 242 ASN F OD1 1 
ATOM   19666 N ND2 . ASN F 1 242 ? 16.648  98.629  15.967  1.00 28.45  ? 242 ASN F ND2 1 
ATOM   19667 N N   . VAL F 1 243 ? 20.108  96.249  13.013  1.00 23.28  ? 243 VAL F N   1 
ATOM   19668 C CA  . VAL F 1 243 ? 20.257  94.982  12.335  1.00 21.48  ? 243 VAL F CA  1 
ATOM   19669 C C   . VAL F 1 243 ? 19.213  93.967  12.794  1.00 23.92  ? 243 VAL F C   1 
ATOM   19670 O O   . VAL F 1 243 ? 18.727  93.161  11.984  1.00 23.72  ? 243 VAL F O   1 
ATOM   19671 C CB  . VAL F 1 243 ? 21.676  94.448  12.521  1.00 21.03  ? 243 VAL F CB  1 
ATOM   19672 C CG1 . VAL F 1 243 ? 21.768  92.995  12.071  1.00 21.62  ? 243 VAL F CG1 1 
ATOM   19673 C CG2 . VAL F 1 243 ? 22.657  95.304  11.745  1.00 20.67  ? 243 VAL F CG2 1 
ATOM   19674 N N   . SER F 1 244 ? 18.886  93.985  14.091  1.00 24.69  ? 244 SER F N   1 
ATOM   19675 C CA  . SER F 1 244 ? 17.972  92.989  14.628  1.00 25.88  ? 244 SER F CA  1 
ATOM   19676 C C   . SER F 1 244 ? 16.544  93.298  14.178  1.00 25.06  ? 244 SER F C   1 
ATOM   19677 O O   . SER F 1 244 ? 15.879  92.425  13.644  1.00 25.20  ? 244 SER F O   1 
ATOM   19678 C CB  . SER F 1 244 ? 18.105  92.861  16.139  1.00 25.58  ? 244 SER F CB  1 
ATOM   19679 O OG  . SER F 1 244 ? 18.032  94.133  16.765  1.00 24.82  ? 244 SER F OG  1 
ATOM   19680 N N   . ALA F 1 245 ? 16.084  94.542  14.365  1.00 26.33  ? 245 ALA F N   1 
ATOM   19681 C CA  . ALA F 1 245 ? 14.747  94.948  13.927  1.00 28.70  ? 245 ALA F CA  1 
ATOM   19682 C C   . ALA F 1 245 ? 14.579  94.688  12.439  1.00 26.17  ? 245 ALA F C   1 
ATOM   19683 O O   . ALA F 1 245 ? 13.529  94.262  12.011  1.00 29.01  ? 245 ALA F O   1 
ATOM   19684 C CB  . ALA F 1 245 ? 14.459  96.421  14.238  1.00 27.95  ? 245 ALA F CB  1 
ATOM   19685 N N   . HIS F 1 246 ? 15.603  95.000  11.660  1.00 24.39  ? 246 HIS F N   1 
ATOM   19686 C CA  . HIS F 1 246 ? 15.474  94.975  10.222  1.00 27.51  ? 246 HIS F CA  1 
ATOM   19687 C C   . HIS F 1 246 ? 15.472  93.518  9.763   1.00 27.21  ? 246 HIS F C   1 
ATOM   19688 O O   . HIS F 1 246 ? 14.761  93.153  8.836   1.00 25.24  ? 246 HIS F O   1 
ATOM   19689 C CB  . HIS F 1 246 ? 16.557  95.867  9.608   1.00 27.63  ? 246 HIS F CB  1 
ATOM   19690 C CG  . HIS F 1 246 ? 16.589  95.827  8.125   1.00 29.64  ? 246 HIS F CG  1 
ATOM   19691 N ND1 . HIS F 1 246 ? 17.706  96.156  7.391   1.00 30.82  ? 246 HIS F ND1 1 
ATOM   19692 C CD2 . HIS F 1 246 ? 15.649  95.520  7.243   1.00 28.55  ? 246 HIS F CD2 1 
ATOM   19693 C CE1 . HIS F 1 246 ? 17.428  96.021  6.107   1.00 29.03  ? 246 HIS F CE1 1 
ATOM   19694 N NE2 . HIS F 1 246 ? 16.194  95.625  6.002   1.00 27.91  ? 246 HIS F NE2 1 
ATOM   19695 N N   . THR F 1 247 ? 16.284  92.679  10.417  1.00 28.80  ? 247 THR F N   1 
ATOM   19696 C CA  . THR F 1 247 ? 16.347  91.272  10.052  1.00 25.66  ? 247 THR F CA  1 
ATOM   19697 C C   . THR F 1 247 ? 14.962  90.683  10.295  1.00 25.23  ? 247 THR F C   1 
ATOM   19698 O O   . THR F 1 247 ? 14.462  89.885  9.510   1.00 26.26  ? 247 THR F O   1 
ATOM   19699 C CB  . THR F 1 247 ? 17.437  90.532  10.835  1.00 24.02  ? 247 THR F CB  1 
ATOM   19700 O OG1 . THR F 1 247 ? 18.752  90.949  10.469  1.00 22.75  ? 247 THR F OG1 1 
ATOM   19701 C CG2 . THR F 1 247 ? 17.418  89.041  10.561  1.00 24.69  ? 247 THR F CG2 1 
ATOM   19702 N N   . ASN F 1 248 ? 14.324  91.141  11.367  1.00 25.47  ? 248 ASN F N   1 
ATOM   19703 C CA  . ASN F 1 248 ? 12.996  90.684  11.740  1.00 26.66  ? 248 ASN F CA  1 
ATOM   19704 C C   . ASN F 1 248 ? 11.973  91.099  10.683  1.00 26.56  ? 248 ASN F C   1 
ATOM   19705 O O   . ASN F 1 248 ? 11.153  90.276  10.270  1.00 27.97  ? 248 ASN F O   1 
ATOM   19706 C CB  . ASN F 1 248 ? 12.632  91.168  13.141  1.00 27.82  ? 248 ASN F CB  1 
ATOM   19707 C CG  . ASN F 1 248 ? 11.252  90.706  13.515  1.00 28.23  ? 248 ASN F CG  1 
ATOM   19708 O OD1 . ASN F 1 248 ? 11.016  89.498  13.692  1.00 28.64  ? 248 ASN F OD1 1 
ATOM   19709 N ND2 . ASN F 1 248 ? 10.337  91.658  13.594  1.00 27.09  ? 248 ASN F ND2 1 
ATOM   19710 N N   . LEU F 1 249 ? 12.054  92.351  10.204  1.00 25.91  ? 249 LEU F N   1 
ATOM   19711 C CA  . LEU F 1 249 ? 11.141  92.834  9.174   1.00 26.78  ? 249 LEU F CA  1 
ATOM   19712 C C   . LEU F 1 249 ? 11.377  92.095  7.858   1.00 26.71  ? 249 LEU F C   1 
ATOM   19713 O O   . LEU F 1 249 ? 10.436  91.692  7.173   1.00 27.03  ? 249 LEU F O   1 
ATOM   19714 C CB  . LEU F 1 249 ? 11.290  94.338  8.976   1.00 28.68  ? 249 LEU F CB  1 
ATOM   19715 C CG  . LEU F 1 249 ? 10.808  95.263  10.099  1.00 29.78  ? 249 LEU F CG  1 
ATOM   19716 C CD1 . LEU F 1 249 ? 11.224  96.664  9.709   1.00 33.24  ? 249 LEU F CD1 1 
ATOM   19717 C CD2 . LEU F 1 249 ? 9.310   95.245  10.362  1.00 29.71  ? 249 LEU F CD2 1 
ATOM   19718 N N   . LEU F 1 250 ? 12.655  91.910  7.515   1.00 26.81  ? 250 LEU F N   1 
ATOM   19719 C CA  . LEU F 1 250 ? 13.032  91.289  6.258   1.00 28.29  ? 250 LEU F CA  1 
ATOM   19720 C C   . LEU F 1 250 ? 12.443  89.885  6.139   1.00 28.00  ? 250 LEU F C   1 
ATOM   19721 O O   . LEU F 1 250 ? 11.843  89.541  5.123   1.00 27.49  ? 250 LEU F O   1 
ATOM   19722 C CB  . LEU F 1 250 ? 14.556  91.284  6.201   1.00 29.82  ? 250 LEU F CB  1 
ATOM   19723 C CG  . LEU F 1 250 ? 15.221  90.628  4.986   1.00 30.69  ? 250 LEU F CG  1 
ATOM   19724 C CD1 . LEU F 1 250 ? 14.608  91.023  3.662   1.00 30.32  ? 250 LEU F CD1 1 
ATOM   19725 C CD2 . LEU F 1 250 ? 16.701  91.008  4.989   1.00 31.98  ? 250 LEU F CD2 1 
ATOM   19726 N N   . VAL F 1 251 ? 12.643  89.082  7.185   1.00 27.76  ? 251 VAL F N   1 
ATOM   19727 C CA  . VAL F 1 251 ? 12.208  87.701  7.188   1.00 25.45  ? 251 VAL F CA  1 
ATOM   19728 C C   . VAL F 1 251 ? 10.691  87.642  7.343   1.00 27.09  ? 251 VAL F C   1 
ATOM   19729 O O   . VAL F 1 251 ? 10.033  86.767  6.776   1.00 28.65  ? 251 VAL F O   1 
ATOM   19730 C CB  . VAL F 1 251 ? 12.937  86.989  8.329   1.00 24.29  ? 251 VAL F CB  1 
ATOM   19731 C CG1 . VAL F 1 251 ? 12.436  85.557  8.513   1.00 25.37  ? 251 VAL F CG1 1 
ATOM   19732 C CG2 . VAL F 1 251 ? 14.429  87.011  8.077   1.00 25.16  ? 251 VAL F CG2 1 
ATOM   19733 N N   . ASN F 1 252 ? 10.138  88.587  8.112   1.00 26.40  ? 252 ASN F N   1 
ATOM   19734 C CA  . ASN F 1 252 ? 8.699   88.717  8.259   1.00 24.59  ? 252 ASN F CA  1 
ATOM   19735 C C   . ASN F 1 252 ? 8.038   88.957  6.895   1.00 25.60  ? 252 ASN F C   1 
ATOM   19736 O O   . ASN F 1 252 ? 6.953   88.454  6.642   1.00 27.60  ? 252 ASN F O   1 
ATOM   19737 C CB  . ASN F 1 252 ? 8.384   89.799  9.280   1.00 24.41  ? 252 ASN F CB  1 
ATOM   19738 C CG  . ASN F 1 252 ? 6.918   90.139  9.300   1.00 26.29  ? 252 ASN F CG  1 
ATOM   19739 O OD1 . ASN F 1 252 ? 6.449   91.000  8.542   1.00 26.83  ? 252 ASN F OD1 1 
ATOM   19740 N ND2 . ASN F 1 252 ? 6.180   89.450  10.153  1.00 26.36  ? 252 ASN F ND2 1 
ATOM   19741 N N   . SER F 1 253 ? 8.705   89.713  6.016   1.00 27.03  ? 253 SER F N   1 
ATOM   19742 C CA  . SER F 1 253 ? 8.165   90.147  4.734   1.00 28.11  ? 253 SER F CA  1 
ATOM   19743 C C   . SER F 1 253 ? 7.885   88.985  3.780   1.00 28.88  ? 253 SER F C   1 
ATOM   19744 O O   . SER F 1 253 ? 7.027   89.081  2.894   1.00 31.33  ? 253 SER F O   1 
ATOM   19745 C CB  . SER F 1 253 ? 9.102   91.161  4.090   1.00 30.13  ? 253 SER F CB  1 
ATOM   19746 O OG  . SER F 1 253 ? 10.243  90.566  3.477   1.00 27.46  ? 253 SER F OG  1 
ATOM   19747 N N   . ALA F 1 254 ? 8.590   87.869  3.954   1.00 28.28  ? 254 ALA F N   1 
ATOM   19748 C CA  . ALA F 1 254 ? 8.302   86.685  3.152   1.00 25.73  ? 254 ALA F CA  1 
ATOM   19749 C C   . ALA F 1 254 ? 7.204   85.822  3.750   1.00 23.25  ? 254 ALA F C   1 
ATOM   19750 O O   . ALA F 1 254 ? 7.014   84.713  3.271   1.00 24.75  ? 254 ALA F O   1 
ATOM   19751 C CB  . ALA F 1 254 ? 9.539   85.854  3.003   1.00 27.62  ? 254 ALA F CB  1 
ATOM   19752 N N   . TYR F 1 255 ? 6.513   86.331  4.780   1.00 24.88  ? 255 TYR F N   1 
ATOM   19753 C CA  . TYR F 1 255 ? 5.477   85.629  5.543   1.00 27.38  ? 255 TYR F CA  1 
ATOM   19754 C C   . TYR F 1 255 ? 6.078   84.537  6.447   1.00 28.04  ? 255 TYR F C   1 
ATOM   19755 O O   . TYR F 1 255 ? 5.407   83.568  6.826   1.00 27.14  ? 255 TYR F O   1 
ATOM   19756 C CB  . TYR F 1 255 ? 4.330   85.095  4.671   1.00 27.86  ? 255 TYR F CB  1 
ATOM   19757 C CG  . TYR F 1 255 ? 3.421   86.122  4.008   1.00 30.78  ? 255 TYR F CG  1 
ATOM   19758 C CD1 . TYR F 1 255 ? 3.495   87.479  4.314   1.00 32.98  ? 255 TYR F CD1 1 
ATOM   19759 C CD2 . TYR F 1 255 ? 2.461   85.725  3.083   1.00 30.99  ? 255 TYR F CD2 1 
ATOM   19760 C CE1 . TYR F 1 255 ? 2.660   88.404  3.706   1.00 34.09  ? 255 TYR F CE1 1 
ATOM   19761 C CE2 . TYR F 1 255 ? 1.620   86.638  2.468   1.00 30.75  ? 255 TYR F CE2 1 
ATOM   19762 C CZ  . TYR F 1 255 ? 1.717   87.980  2.784   1.00 35.20  ? 255 TYR F CZ  1 
ATOM   19763 O OH  . TYR F 1 255 ? 0.883   88.892  2.202   1.00 41.40  ? 255 TYR F OH  1 
ATOM   19764 N N   . SER F 1 256 ? 7.331   84.711  6.864   1.00 26.38  ? 256 SER F N   1 
ATOM   19765 C CA  . SER F 1 256 ? 7.845   83.822  7.888   1.00 29.13  ? 256 SER F CA  1 
ATOM   19766 C C   . SER F 1 256 ? 7.290   84.257  9.250   1.00 27.98  ? 256 SER F C   1 
ATOM   19767 O O   . SER F 1 256 ? 7.148   85.465  9.497   1.00 21.90  ? 256 SER F O   1 
ATOM   19768 C CB  . SER F 1 256 ? 9.343   83.782  7.865   1.00 26.95  ? 256 SER F CB  1 
ATOM   19769 O OG  . SER F 1 256 ? 9.776   83.184  6.660   1.00 28.63  ? 256 SER F OG  1 
ATOM   19770 N N   . ASP F 1 257 ? 6.984   83.264  10.119  1.00 27.73  ? 257 ASP F N   1 
ATOM   19771 C CA  . ASP F 1 257 ? 6.377   83.543  11.424  1.00 27.59  ? 257 ASP F CA  1 
ATOM   19772 C C   . ASP F 1 257 ? 7.406   84.130  12.385  1.00 24.81  ? 257 ASP F C   1 
ATOM   19773 O O   . ASP F 1 257 ? 8.588   84.099  12.104  1.00 26.32  ? 257 ASP F O   1 
ATOM   19774 C CB  . ASP F 1 257 ? 5.753   82.306  12.035  1.00 25.93  ? 257 ASP F CB  1 
ATOM   19775 C CG  . ASP F 1 257 ? 6.754   81.194  12.233  1.00 27.64  ? 257 ASP F CG  1 
ATOM   19776 O OD1 . ASP F 1 257 ? 7.621   81.349  13.114  1.00 29.32  ? 257 ASP F OD1 1 
ATOM   19777 O OD2 . ASP F 1 257 ? 6.700   80.238  11.450  1.00 27.58  ? 257 ASP F OD2 1 
ATOM   19778 N N   . ILE F 1 258 ? 6.943   84.612  13.543  1.00 26.41  ? 258 ILE F N   1 
ATOM   19779 C CA  . ILE F 1 258 ? 7.763   85.367  14.489  1.00 23.53  ? 258 ILE F CA  1 
ATOM   19780 C C   . ILE F 1 258 ? 8.896   84.508  15.051  1.00 23.37  ? 258 ILE F C   1 
ATOM   19781 O O   . ILE F 1 258 ? 9.968   85.030  15.323  1.00 20.96  ? 258 ILE F O   1 
ATOM   19782 C CB  . ILE F 1 258 ? 6.883   85.961  15.607  1.00 22.48  ? 258 ILE F CB  1 
ATOM   19783 C CG1 . ILE F 1 258 ? 7.619   86.977  16.420  1.00 19.82  ? 258 ILE F CG1 1 
ATOM   19784 C CG2 . ILE F 1 258 ? 6.282   84.873  16.507  1.00 24.17  ? 258 ILE F CG2 1 
ATOM   19785 C CD1 . ILE F 1 258 ? 7.905   88.265  15.689  1.00 20.19  ? 258 ILE F CD1 1 
ATOM   19786 N N   . TYR F 1 259 ? 8.663   83.195  15.228  1.00 23.88  ? 259 TYR F N   1 
ATOM   19787 C CA  . TYR F 1 259 ? 9.715   82.314  15.703  1.00 23.68  ? 259 TYR F CA  1 
ATOM   19788 C C   . TYR F 1 259 ? 10.874  82.334  14.702  1.00 25.54  ? 259 TYR F C   1 
ATOM   19789 O O   . TYR F 1 259 ? 12.034  82.378  15.123  1.00 24.36  ? 259 TYR F O   1 
ATOM   19790 C CB  . TYR F 1 259 ? 9.261   80.881  15.972  1.00 23.35  ? 259 TYR F CB  1 
ATOM   19791 C CG  . TYR F 1 259 ? 8.217   80.807  17.070  1.00 26.91  ? 259 TYR F CG  1 
ATOM   19792 C CD1 . TYR F 1 259 ? 6.860   80.897  16.757  1.00 28.30  ? 259 TYR F CD1 1 
ATOM   19793 C CD2 . TYR F 1 259 ? 8.571   80.648  18.409  1.00 27.18  ? 259 TYR F CD2 1 
ATOM   19794 C CE1 . TYR F 1 259 ? 5.886   80.850  17.737  1.00 26.58  ? 259 TYR F CE1 1 
ATOM   19795 C CE2 . TYR F 1 259 ? 7.601   80.617  19.402  1.00 28.51  ? 259 TYR F CE2 1 
ATOM   19796 C CZ  . TYR F 1 259 ? 6.256   80.712  19.061  1.00 28.00  ? 259 TYR F CZ  1 
ATOM   19797 O OH  . TYR F 1 259 ? 5.244   80.659  19.984  1.00 28.48  ? 259 TYR F OH  1 
ATOM   19798 N N   . ARG F 1 260 ? 10.564  82.300  13.389  1.00 24.40  ? 260 ARG F N   1 
ATOM   19799 C CA  . ARG F 1 260 ? 11.596  82.340  12.361  1.00 24.64  ? 260 ARG F CA  1 
ATOM   19800 C C   . ARG F 1 260 ? 12.187  83.747  12.261  1.00 23.32  ? 260 ARG F C   1 
ATOM   19801 O O   . ARG F 1 260 ? 13.410  83.894  12.245  1.00 25.19  ? 260 ARG F O   1 
ATOM   19802 C CB  . ARG F 1 260 ? 11.097  81.778  11.020  1.00 27.84  ? 260 ARG F CB  1 
ATOM   19803 C CG  . ARG F 1 260 ? 10.799  80.293  11.169  1.00 28.54  ? 260 ARG F CG  1 
ATOM   19804 C CD  . ARG F 1 260 ? 10.977  79.365  9.974   1.00 26.02  ? 260 ARG F CD  1 
ATOM   19805 N NE  . ARG F 1 260 ? 9.712   79.057  9.320   1.00 26.35  ? 260 ARG F NE  1 
ATOM   19806 C CZ  . ARG F 1 260 ? 9.220   77.914  8.775   1.00 26.65  ? 260 ARG F CZ  1 
ATOM   19807 N NH1 . ARG F 1 260 ? 9.809   76.736  8.783   1.00 24.62  ? 260 ARG F NH1 1 
ATOM   19808 N NH2 . ARG F 1 260 ? 8.029   77.969  8.219   1.00 26.45  ? 260 ARG F NH2 1 
ATOM   19809 N N   . SER F 1 261 ? 11.340  84.780  12.203  1.00 20.92  ? 261 SER F N   1 
ATOM   19810 C CA  . SER F 1 261 ? 11.840  86.135  12.038  1.00 23.56  ? 261 SER F CA  1 
ATOM   19811 C C   . SER F 1 261 ? 12.661  86.596  13.237  1.00 24.86  ? 261 SER F C   1 
ATOM   19812 O O   . SER F 1 261 ? 13.642  87.313  13.054  1.00 24.97  ? 261 SER F O   1 
ATOM   19813 C CB  . SER F 1 261 ? 10.733  87.131  11.731  1.00 25.27  ? 261 SER F CB  1 
ATOM   19814 O OG  . SER F 1 261 ? 9.970   87.506  12.869  1.00 26.79  ? 261 SER F OG  1 
ATOM   19815 N N   . PHE F 1 262 ? 12.272  86.187  14.463  1.00 26.25  ? 262 PHE F N   1 
ATOM   19816 C CA  . PHE F 1 262 ? 12.924  86.706  15.658  1.00 24.97  ? 262 PHE F CA  1 
ATOM   19817 C C   . PHE F 1 262 ? 14.210  85.923  15.971  1.00 24.78  ? 262 PHE F C   1 
ATOM   19818 O O   . PHE F 1 262 ? 15.228  86.509  16.313  1.00 24.36  ? 262 PHE F O   1 
ATOM   19819 C CB  . PHE F 1 262 ? 11.945  86.797  16.827  1.00 24.32  ? 262 PHE F CB  1 
ATOM   19820 C CG  . PHE F 1 262 ? 12.619  87.428  18.028  1.00 24.87  ? 262 PHE F CG  1 
ATOM   19821 C CD1 . PHE F 1 262 ? 12.983  88.765  18.011  1.00 25.14  ? 262 PHE F CD1 1 
ATOM   19822 C CD2 . PHE F 1 262 ? 12.970  86.671  19.129  1.00 26.23  ? 262 PHE F CD2 1 
ATOM   19823 C CE1 . PHE F 1 262 ? 13.625  89.339  19.087  1.00 24.41  ? 262 PHE F CE1 1 
ATOM   19824 C CE2 . PHE F 1 262 ? 13.611  87.268  20.209  1.00 26.39  ? 262 PHE F CE2 1 
ATOM   19825 C CZ  . PHE F 1 262 ? 13.951  88.591  20.173  1.00 23.66  ? 262 PHE F CZ  1 
ATOM   19826 N N   . SER F 1 263 ? 14.207  84.598  15.833  1.00 23.66  ? 263 SER F N   1 
ATOM   19827 C CA  . SER F 1 263 ? 15.449  83.855  15.971  1.00 23.06  ? 263 SER F CA  1 
ATOM   19828 C C   . SER F 1 263 ? 16.473  84.370  14.958  1.00 25.28  ? 263 SER F C   1 
ATOM   19829 O O   . SER F 1 263 ? 17.645  84.558  15.271  1.00 27.85  ? 263 SER F O   1 
ATOM   19830 C CB  . SER F 1 263 ? 15.214  82.372  15.815  1.00 21.94  ? 263 SER F CB  1 
ATOM   19831 O OG  . SER F 1 263 ? 14.636  82.056  14.554  1.00 20.88  ? 263 SER F OG  1 
ATOM   19832 N N   . ALA F 1 264 ? 16.008  84.619  13.732  1.00 24.97  ? 264 ALA F N   1 
ATOM   19833 C CA  . ALA F 1 264 ? 16.819  85.264  12.717  1.00 25.38  ? 264 ALA F CA  1 
ATOM   19834 C C   . ALA F 1 264 ? 17.391  86.580  13.237  1.00 22.98  ? 264 ALA F C   1 
ATOM   19835 O O   . ALA F 1 264 ? 18.568  86.862  13.058  1.00 22.36  ? 264 ALA F O   1 
ATOM   19836 C CB  . ALA F 1 264 ? 15.979  85.479  11.479  1.00 26.73  ? 264 ALA F CB  1 
ATOM   19837 N N   . ALA F 1 265 ? 16.542  87.406  13.836  1.00 22.15  ? 265 ALA F N   1 
ATOM   19838 C CA  . ALA F 1 265 ? 16.982  88.708  14.292  1.00 23.24  ? 265 ALA F CA  1 
ATOM   19839 C C   . ALA F 1 265 ? 18.031  88.550  15.395  1.00 27.06  ? 265 ALA F C   1 
ATOM   19840 O O   . ALA F 1 265 ? 18.932  89.405  15.536  1.00 28.39  ? 265 ALA F O   1 
ATOM   19841 C CB  . ALA F 1 265 ? 15.794  89.535  14.755  1.00 23.43  ? 265 ALA F CB  1 
ATOM   19842 N N   . MET F 1 266 ? 17.927  87.454  16.165  1.00 25.76  ? 266 MET F N   1 
ATOM   19843 C CA  . MET F 1 266 ? 18.856  87.221  17.269  1.00 24.92  ? 266 MET F CA  1 
ATOM   19844 C C   . MET F 1 266 ? 20.238  86.841  16.745  1.00 22.80  ? 266 MET F C   1 
ATOM   19845 O O   . MET F 1 266 ? 21.234  87.259  17.326  1.00 22.54  ? 266 MET F O   1 
ATOM   19846 C CB  . MET F 1 266 ? 18.357  86.135  18.227  1.00 24.65  ? 266 MET F CB  1 
ATOM   19847 C CG  . MET F 1 266 ? 17.165  86.531  19.076  1.00 22.26  ? 266 MET F CG  1 
ATOM   19848 S SD  . MET F 1 266 ? 17.409  87.996  20.089  1.00 24.97  ? 266 MET F SD  1 
ATOM   19849 C CE  . MET F 1 266 ? 16.879  89.330  19.010  1.00 23.34  ? 266 MET F CE  1 
ATOM   19850 N N   . ASN F 1 267 ? 20.305  86.081  15.644  1.00 22.58  ? 267 ASN F N   1 
ATOM   19851 C CA  . ASN F 1 267 ? 21.573  85.840  14.956  1.00 23.07  ? 267 ASN F CA  1 
ATOM   19852 C C   . ASN F 1 267 ? 22.230  87.160  14.512  1.00 23.50  ? 267 ASN F C   1 
ATOM   19853 O O   . ASN F 1 267 ? 23.450  87.263  14.382  1.00 23.36  ? 267 ASN F O   1 
ATOM   19854 C CB  . ASN F 1 267 ? 21.379  84.884  13.782  1.00 23.56  ? 267 ASN F CB  1 
ATOM   19855 C CG  . ASN F 1 267 ? 21.005  83.490  14.221  1.00 24.93  ? 267 ASN F CG  1 
ATOM   19856 O OD1 . ASN F 1 267 ? 20.946  83.204  15.420  1.00 23.70  ? 267 ASN F OD1 1 
ATOM   19857 N ND2 . ASN F 1 267 ? 20.739  82.612  13.266  1.00 25.30  ? 267 ASN F ND2 1 
ATOM   19858 N N   . GLY F 1 268 ? 21.434  88.211  14.286  1.00 24.97  ? 268 GLY F N   1 
ATOM   19859 C CA  . GLY F 1 268 ? 22.002  89.510  13.949  1.00 25.80  ? 268 GLY F CA  1 
ATOM   19860 C C   . GLY F 1 268 ? 22.433  90.312  15.175  1.00 24.52  ? 268 GLY F C   1 
ATOM   19861 O O   . GLY F 1 268 ? 23.452  90.999  15.175  1.00 22.62  ? 268 GLY F O   1 
ATOM   19862 N N   . LEU F 1 269 ? 21.606  90.258  16.219  1.00 26.49  ? 269 LEU F N   1 
ATOM   19863 C CA  . LEU F 1 269 ? 21.929  90.897  17.488  1.00 24.46  ? 269 LEU F CA  1 
ATOM   19864 C C   . LEU F 1 269 ? 23.243  90.352  18.061  1.00 23.47  ? 269 LEU F C   1 
ATOM   19865 O O   . LEU F 1 269 ? 23.991  91.111  18.672  1.00 21.26  ? 269 LEU F O   1 
ATOM   19866 C CB  . LEU F 1 269 ? 20.779  90.728  18.470  1.00 21.77  ? 269 LEU F CB  1 
ATOM   19867 C CG  . LEU F 1 269 ? 20.849  91.610  19.715  1.00 20.75  ? 269 LEU F CG  1 
ATOM   19868 C CD1 . LEU F 1 269 ? 20.644  93.085  19.399  1.00 21.48  ? 269 LEU F CD1 1 
ATOM   19869 C CD2 . LEU F 1 269 ? 19.857  91.140  20.742  1.00 20.30  ? 269 LEU F CD2 1 
ATOM   19870 N N   . ALA F 1 270 ? 23.527  89.068  17.800  1.00 22.56  ? 270 ALA F N   1 
ATOM   19871 C CA  . ALA F 1 270 ? 24.720  88.398  18.297  1.00 24.44  ? 270 ALA F CA  1 
ATOM   19872 C C   . ALA F 1 270 ? 26.008  88.910  17.660  1.00 26.38  ? 270 ALA F C   1 
ATOM   19873 O O   . ALA F 1 270 ? 27.085  88.452  18.026  1.00 27.26  ? 270 ALA F O   1 
ATOM   19874 C CB  . ALA F 1 270 ? 24.612  86.894  18.078  1.00 23.68  ? 270 ALA F CB  1 
ATOM   19875 N N   . GLY F 1 271 ? 25.912  89.775  16.650  1.00 27.59  ? 271 GLY F N   1 
ATOM   19876 C CA  . GLY F 1 271 ? 27.118  90.261  16.011  1.00 26.73  ? 271 GLY F CA  1 
ATOM   19877 C C   . GLY F 1 271 ? 27.859  91.266  16.893  1.00 25.64  ? 271 GLY F C   1 
ATOM   19878 O O   . GLY F 1 271 ? 27.248  92.150  17.492  1.00 24.43  ? 271 GLY F O   1 
ATOM   19879 N N   . PRO F 1 272 ? 29.201  91.169  16.975  1.00 24.10  ? 272 PRO F N   1 
ATOM   19880 C CA  . PRO F 1 272 ? 30.027  92.173  17.649  1.00 23.57  ? 272 PRO F CA  1 
ATOM   19881 C C   . PRO F 1 272 ? 29.689  93.641  17.444  1.00 24.61  ? 272 PRO F C   1 
ATOM   19882 O O   . PRO F 1 272 ? 29.878  94.434  18.349  1.00 25.98  ? 272 PRO F O   1 
ATOM   19883 C CB  . PRO F 1 272 ? 31.401  91.836  17.060  1.00 26.02  ? 272 PRO F CB  1 
ATOM   19884 C CG  . PRO F 1 272 ? 31.392  90.331  16.945  1.00 26.18  ? 272 PRO F CG  1 
ATOM   19885 C CD  . PRO F 1 272 ? 29.985  90.037  16.465  1.00 25.59  ? 272 PRO F CD  1 
ATOM   19886 N N   . LEU F 1 273 ? 29.212  94.012  16.256  1.00 27.98  ? 273 LEU F N   1 
ATOM   19887 C CA  . LEU F 1 273 ? 28.933  95.410  15.954  1.00 29.69  ? 273 LEU F CA  1 
ATOM   19888 C C   . LEU F 1 273 ? 27.517  95.789  16.369  1.00 26.26  ? 273 LEU F C   1 
ATOM   19889 O O   . LEU F 1 273 ? 27.182  96.964  16.329  1.00 22.67  ? 273 LEU F O   1 
ATOM   19890 C CB  . LEU F 1 273 ? 29.153  95.703  14.468  1.00 34.20  ? 273 LEU F CB  1 
ATOM   19891 C CG  . LEU F 1 273 ? 30.600  95.588  13.955  1.00 37.84  ? 273 LEU F CG  1 
ATOM   19892 C CD1 . LEU F 1 273 ? 30.696  95.967  12.482  1.00 34.05  ? 273 LEU F CD1 1 
ATOM   19893 C CD2 . LEU F 1 273 ? 31.600  96.418  14.773  1.00 38.55  ? 273 LEU F CD2 1 
ATOM   19894 N N   . HIS F 1 274 ? 26.671  94.792  16.660  1.00 27.51  ? 274 HIS F N   1 
ATOM   19895 C CA  . HIS F 1 274 ? 25.295  95.022  17.091  1.00 26.62  ? 274 HIS F CA  1 
ATOM   19896 C C   . HIS F 1 274 ? 25.233  94.742  18.600  1.00 30.06  ? 274 HIS F C   1 
ATOM   19897 O O   . HIS F 1 274 ? 26.058  95.273  19.344  1.00 28.19  ? 274 HIS F O   1 
ATOM   19898 C CB  . HIS F 1 274 ? 24.323  94.278  16.165  1.00 25.52  ? 274 HIS F CB  1 
ATOM   19899 C CG  . HIS F 1 274 ? 22.863  94.601  16.339  1.00 24.88  ? 274 HIS F CG  1 
ATOM   19900 N ND1 . HIS F 1 274 ? 22.403  95.801  16.826  1.00 23.07  ? 274 HIS F ND1 1 
ATOM   19901 C CD2 . HIS F 1 274 ? 21.753  93.874  16.088  1.00 24.42  ? 274 HIS F CD2 1 
ATOM   19902 C CE1 . HIS F 1 274 ? 21.082  95.783  16.899  1.00 22.34  ? 274 HIS F CE1 1 
ATOM   19903 N NE2 . HIS F 1 274 ? 20.669  94.633  16.443  1.00 22.67  ? 274 HIS F NE2 1 
ATOM   19904 N N   . GLY F 1 275 ? 24.319  93.864  19.052  1.00 31.92  ? 275 GLY F N   1 
ATOM   19905 C CA  . GLY F 1 275 ? 24.034  93.688  20.471  1.00 30.91  ? 275 GLY F CA  1 
ATOM   19906 C C   . GLY F 1 275 ? 25.208  93.126  21.283  1.00 28.58  ? 275 GLY F C   1 
ATOM   19907 O O   . GLY F 1 275 ? 25.277  93.349  22.485  1.00 28.60  ? 275 GLY F O   1 
ATOM   19908 N N   . LEU F 1 276 ? 26.104  92.374  20.640  1.00 27.91  ? 276 LEU F N   1 
ATOM   19909 C CA  . LEU F 1 276 ? 27.175  91.659  21.330  1.00 29.90  ? 276 LEU F CA  1 
ATOM   19910 C C   . LEU F 1 276 ? 28.156  92.652  21.939  1.00 28.88  ? 276 LEU F C   1 
ATOM   19911 O O   . LEU F 1 276 ? 28.965  92.286  22.777  1.00 32.40  ? 276 LEU F O   1 
ATOM   19912 C CB  . LEU F 1 276 ? 27.932  90.678  20.434  1.00 28.38  ? 276 LEU F CB  1 
ATOM   19913 C CG  . LEU F 1 276 ? 28.738  89.579  21.137  1.00 29.80  ? 276 LEU F CG  1 
ATOM   19914 C CD1 . LEU F 1 276 ? 27.891  88.436  21.659  1.00 31.13  ? 276 LEU F CD1 1 
ATOM   19915 C CD2 . LEU F 1 276 ? 29.804  89.020  20.214  1.00 31.46  ? 276 LEU F CD2 1 
ATOM   19916 N N   . ALA F 1 277 ? 28.053  93.915  21.554  1.00 28.50  ? 277 ALA F N   1 
ATOM   19917 C CA  . ALA F 1 277 ? 28.878  94.947  22.144  1.00 29.10  ? 277 ALA F CA  1 
ATOM   19918 C C   . ALA F 1 277 ? 28.685  95.042  23.669  1.00 29.40  ? 277 ALA F C   1 
ATOM   19919 O O   . ALA F 1 277 ? 29.582  95.497  24.373  1.00 31.52  ? 277 ALA F O   1 
ATOM   19920 C CB  . ALA F 1 277 ? 28.550  96.252  21.441  1.00 28.13  ? 277 ALA F CB  1 
ATOM   19921 N N   . ASN F 1 278 ? 27.512  94.670  24.200  1.00 26.95  ? 278 ASN F N   1 
ATOM   19922 C CA  . ASN F 1 278 ? 27.291  94.783  25.631  1.00 25.39  ? 278 ASN F CA  1 
ATOM   19923 C C   . ASN F 1 278 ? 28.156  93.763  26.351  1.00 24.85  ? 278 ASN F C   1 
ATOM   19924 O O   . ASN F 1 278 ? 28.650  94.038  27.431  1.00 19.79  ? 278 ASN F O   1 
ATOM   19925 C CB  . ASN F 1 278 ? 25.811  94.846  25.993  1.00 27.31  ? 278 ASN F CB  1 
ATOM   19926 C CG  . ASN F 1 278 ? 25.030  93.554  25.924  1.00 27.85  ? 278 ASN F CG  1 
ATOM   19927 O OD1 . ASN F 1 278 ? 23.816  93.578  26.182  1.00 31.53  ? 278 ASN F OD1 1 
ATOM   19928 N ND2 . ASN F 1 278 ? 25.656  92.443  25.578  1.00 25.01  ? 278 ASN F ND2 1 
ATOM   19929 N N   . GLN F 1 279 ? 28.432  92.641  25.680  1.00 29.10  ? 279 GLN F N   1 
ATOM   19930 C CA  . GLN F 1 279 ? 29.401  91.660  26.157  1.00 32.69  ? 279 GLN F CA  1 
ATOM   19931 C C   . GLN F 1 279 ? 30.845  92.175  25.976  1.00 33.04  ? 279 GLN F C   1 
ATOM   19932 O O   . GLN F 1 279 ? 31.733  91.957  26.805  1.00 32.45  ? 279 GLN F O   1 
ATOM   19933 C CB  . GLN F 1 279 ? 29.134  90.359  25.380  1.00 28.41  ? 279 GLN F CB  1 
ATOM   19934 C CG  . GLN F 1 279 ? 30.267  89.343  25.499  1.00 27.19  ? 279 GLN F CG  1 
ATOM   19935 C CD  . GLN F 1 279 ? 30.145  88.219  24.497  1.00 26.32  ? 279 GLN F CD  1 
ATOM   19936 O OE1 . GLN F 1 279 ? 29.161  87.463  24.500  1.00 26.00  ? 279 GLN F OE1 1 
ATOM   19937 N NE2 . GLN F 1 279 ? 31.133  88.128  23.619  1.00 23.38  ? 279 GLN F NE2 1 
ATOM   19938 N N   . GLU F 1 280 ? 31.072  92.815  24.828  1.00 32.48  ? 280 GLU F N   1 
ATOM   19939 C CA  . GLU F 1 280 ? 32.393  93.190  24.384  1.00 30.86  ? 280 GLU F CA  1 
ATOM   19940 C C   . GLU F 1 280 ? 32.872  94.342  25.254  1.00 30.80  ? 280 GLU F C   1 
ATOM   19941 O O   . GLU F 1 280 ? 34.065  94.405  25.557  1.00 31.84  ? 280 GLU F O   1 
ATOM   19942 C CB  . GLU F 1 280 ? 32.364  93.539  22.897  1.00 29.87  ? 280 GLU F CB  1 
ATOM   19943 C CG  . GLU F 1 280 ? 32.150  92.323  22.002  1.00 28.87  ? 280 GLU F CG  1 
ATOM   19944 C CD  . GLU F 1 280 ? 33.271  91.322  22.063  1.00 30.31  ? 280 GLU F CD  1 
ATOM   19945 O OE1 . GLU F 1 280 ? 33.090  90.257  22.663  1.00 33.05  ? 280 GLU F OE1 1 
ATOM   19946 O OE2 . GLU F 1 280 ? 34.343  91.617  21.516  1.00 37.05  ? 280 GLU F OE2 1 
ATOM   19947 N N   . VAL F 1 281 ? 31.933  95.207  25.661  1.00 29.13  ? 281 VAL F N   1 
ATOM   19948 C CA  . VAL F 1 281 ? 32.261  96.326  26.522  1.00 36.06  ? 281 VAL F CA  1 
ATOM   19949 C C   . VAL F 1 281 ? 32.906  95.787  27.802  1.00 42.02  ? 281 VAL F C   1 
ATOM   19950 O O   . VAL F 1 281 ? 33.939  96.304  28.230  1.00 40.79  ? 281 VAL F O   1 
ATOM   19951 C CB  . VAL F 1 281 ? 31.066  97.225  26.888  1.00 35.07  ? 281 VAL F CB  1 
ATOM   19952 C CG1 . VAL F 1 281 ? 31.401  98.130  28.066  1.00 31.36  ? 281 VAL F CG1 1 
ATOM   19953 C CG2 . VAL F 1 281 ? 30.615  98.057  25.703  1.00 36.81  ? 281 VAL F CG2 1 
ATOM   19954 N N   . LEU F 1 282 ? 32.301  94.751  28.402  1.00 38.18  ? 282 LEU F N   1 
ATOM   19955 C CA  . LEU F 1 282 ? 32.781  94.254  29.680  1.00 41.43  ? 282 LEU F CA  1 
ATOM   19956 C C   . LEU F 1 282 ? 34.092  93.492  29.513  1.00 39.19  ? 282 LEU F C   1 
ATOM   19957 O O   . LEU F 1 282 ? 34.980  93.619  30.338  1.00 40.68  ? 282 LEU F O   1 
ATOM   19958 C CB  . LEU F 1 282 ? 31.767  93.403  30.444  1.00 42.92  ? 282 LEU F CB  1 
ATOM   19959 C CG  . LEU F 1 282 ? 32.051  93.335  31.945  1.00 45.39  ? 282 LEU F CG  1 
ATOM   19960 C CD1 . LEU F 1 282 ? 31.862  94.679  32.583  1.00 45.99  ? 282 LEU F CD1 1 
ATOM   19961 C CD2 . LEU F 1 282 ? 31.164  92.376  32.610  1.00 54.36  ? 282 LEU F CD2 1 
ATOM   19962 N N   . ARG F 1 283 ? 34.213  92.689  28.461  1.00 41.82  ? 283 ARG F N   1 
ATOM   19963 C CA  . ARG F 1 283 ? 35.454  91.985  28.214  1.00 40.67  ? 283 ARG F CA  1 
ATOM   19964 C C   . ARG F 1 283 ? 36.595  93.000  28.107  1.00 37.70  ? 283 ARG F C   1 
ATOM   19965 O O   . ARG F 1 283 ? 37.714  92.743  28.543  1.00 38.61  ? 283 ARG F O   1 
ATOM   19966 C CB  . ARG F 1 283 ? 35.271  91.098  26.977  1.00 45.50  ? 283 ARG F CB  1 
ATOM   19967 C CG  . ARG F 1 283 ? 36.340  90.022  26.777  1.00 55.30  ? 283 ARG F CG  1 
ATOM   19968 C CD  . ARG F 1 283 ? 36.022  89.003  25.651  1.00 55.76  ? 283 ARG F CD  1 
ATOM   19969 N NE  . ARG F 1 283 ? 35.975  89.594  24.302  1.00 57.26  ? 283 ARG F NE  1 
ATOM   19970 C CZ  . ARG F 1 283 ? 36.987  89.844  23.460  1.00 48.00  ? 283 ARG F CZ  1 
ATOM   19971 N NH1 . ARG F 1 283 ? 38.187  89.357  23.697  1.00 48.02  ? 283 ARG F NH1 1 
ATOM   19972 N NH2 . ARG F 1 283 ? 36.774  90.531  22.346  1.00 45.40  ? 283 ARG F NH2 1 
ATOM   19973 N N   . TRP F 1 284 ? 36.304  94.157  27.514  1.00 37.11  ? 284 TRP F N   1 
ATOM   19974 C CA  . TRP F 1 284 ? 37.305  95.176  27.244  1.00 34.75  ? 284 TRP F CA  1 
ATOM   19975 C C   . TRP F 1 284 ? 37.710  95.888  28.528  1.00 38.51  ? 284 TRP F C   1 
ATOM   19976 O O   . TRP F 1 284 ? 38.901  96.124  28.711  1.00 42.97  ? 284 TRP F O   1 
ATOM   19977 C CB  . TRP F 1 284 ? 36.735  96.177  26.235  1.00 33.58  ? 284 TRP F CB  1 
ATOM   19978 C CG  . TRP F 1 284 ? 37.657  97.290  25.816  1.00 32.57  ? 284 TRP F CG  1 
ATOM   19979 C CD1 . TRP F 1 284 ? 38.528  97.252  24.775  1.00 32.28  ? 284 TRP F CD1 1 
ATOM   19980 C CD2 . TRP F 1 284 ? 37.748  98.626  26.365  1.00 34.05  ? 284 TRP F CD2 1 
ATOM   19981 N NE1 . TRP F 1 284 ? 39.155  98.460  24.641  1.00 32.73  ? 284 TRP F NE1 1 
ATOM   19982 C CE2 . TRP F 1 284 ? 38.715  99.316  25.604  1.00 30.41  ? 284 TRP F CE2 1 
ATOM   19983 C CE3 . TRP F 1 284 ? 37.116  99.308  27.416  1.00 35.60  ? 284 TRP F CE3 1 
ATOM   19984 C CZ2 . TRP F 1 284 ? 39.058  100.641 25.855  1.00 33.20  ? 284 TRP F CZ2 1 
ATOM   19985 C CZ3 . TRP F 1 284 ? 37.454  100.625 27.657  1.00 33.89  ? 284 TRP F CZ3 1 
ATOM   19986 C CH2 . TRP F 1 284 ? 38.398  101.285 26.879  1.00 31.47  ? 284 TRP F CH2 1 
ATOM   19987 N N   . ILE F 1 285 ? 36.715  96.258  29.363  1.00 39.12  ? 285 ILE F N   1 
ATOM   19988 C CA  . ILE F 1 285 ? 36.934  96.829  30.686  1.00 39.44  ? 285 ILE F CA  1 
ATOM   19989 C C   . ILE F 1 285 ? 37.753  95.862  31.539  1.00 40.61  ? 285 ILE F C   1 
ATOM   19990 O O   . ILE F 1 285 ? 38.641  96.292  32.266  1.00 37.82  ? 285 ILE F O   1 
ATOM   19991 C CB  . ILE F 1 285 ? 35.611  97.202  31.381  1.00 43.47  ? 285 ILE F CB  1 
ATOM   19992 C CG1 . ILE F 1 285 ? 34.956  98.407  30.758  1.00 43.10  ? 285 ILE F CG1 1 
ATOM   19993 C CG2 . ILE F 1 285 ? 35.808  97.451  32.879  1.00 46.43  ? 285 ILE F CG2 1 
ATOM   19994 C CD1 . ILE F 1 285 ? 33.598  98.751  31.355  1.00 46.20  ? 285 ILE F CD1 1 
ATOM   19995 N N   . GLN F 1 286 ? 37.452  94.565  31.446  1.00 41.25  ? 286 GLN F N   1 
ATOM   19996 C CA  . GLN F 1 286 ? 38.164  93.550  32.202  1.00 45.36  ? 286 GLN F CA  1 
ATOM   19997 C C   . GLN F 1 286 ? 39.655  93.573  31.845  1.00 50.59  ? 286 GLN F C   1 
ATOM   19998 O O   . GLN F 1 286 ? 40.488  93.650  32.747  1.00 55.02  ? 286 GLN F O   1 
ATOM   19999 C CB  . GLN F 1 286 ? 37.437  92.215  32.015  1.00 50.69  ? 286 GLN F CB  1 
ATOM   20000 C CG  . GLN F 1 286 ? 38.109  91.010  32.670  1.00 56.65  ? 286 GLN F CG  1 
ATOM   20001 C CD  . GLN F 1 286 ? 37.364  89.702  32.460  1.00 67.04  ? 286 GLN F CD  1 
ATOM   20002 O OE1 . GLN F 1 286 ? 37.370  89.109  31.369  1.00 60.44  ? 286 GLN F OE1 1 
ATOM   20003 N NE2 . GLN F 1 286 ? 36.723  89.221  33.521  1.00 67.62  ? 286 GLN F NE2 1 
ATOM   20004 N N   . MET F 1 287 ? 39.994  93.531  30.543  1.00 52.73  ? 287 MET F N   1 
ATOM   20005 C CA  . MET F 1 287 ? 41.383  93.534  30.081  1.00 50.79  ? 287 MET F CA  1 
ATOM   20006 C C   . MET F 1 287 ? 42.143  94.781  30.558  1.00 47.06  ? 287 MET F C   1 
ATOM   20007 O O   . MET F 1 287 ? 43.305  94.673  30.940  1.00 48.47  ? 287 MET F O   1 
ATOM   20008 C CB  . MET F 1 287 ? 41.462  93.444  28.551  1.00 50.03  ? 287 MET F CB  1 
ATOM   20009 C CG  . MET F 1 287 ? 41.140  92.078  28.002  1.00 53.91  ? 287 MET F CG  1 
ATOM   20010 S SD  . MET F 1 287 ? 41.381  91.986  26.215  1.00 67.51  ? 287 MET F SD  1 
ATOM   20011 C CE  . MET F 1 287 ? 40.045  92.859  25.380  1.00 67.94  ? 287 MET F CE  1 
ATOM   20012 N N   . LEU F 1 288 ? 41.488  95.948  30.457  1.00 44.11  ? 288 LEU F N   1 
ATOM   20013 C CA  . LEU F 1 288 ? 41.886  97.211  31.049  1.00 45.37  ? 288 LEU F CA  1 
ATOM   20014 C C   . LEU F 1 288 ? 42.327  97.006  32.500  1.00 58.77  ? 288 LEU F C   1 
ATOM   20015 O O   . LEU F 1 288 ? 43.437  97.388  32.886  1.00 59.58  ? 288 LEU F O   1 
ATOM   20016 C CB  . LEU F 1 288 ? 40.665  98.129  31.048  1.00 40.54  ? 288 LEU F CB  1 
ATOM   20017 C CG  . LEU F 1 288 ? 40.876  99.614  30.743  1.00 45.37  ? 288 LEU F CG  1 
ATOM   20018 C CD1 . LEU F 1 288 ? 39.987  100.434 31.668  1.00 43.29  ? 288 LEU F CD1 1 
ATOM   20019 C CD2 . LEU F 1 288 ? 42.315  100.122 30.757  1.00 44.64  ? 288 LEU F CD2 1 
ATOM   20020 N N   . TYR F 1 289 ? 41.403  96.448  33.297  1.00 59.48  ? 289 TYR F N   1 
ATOM   20021 C CA  . TYR F 1 289 ? 41.491  96.439  34.750  1.00 65.86  ? 289 TYR F CA  1 
ATOM   20022 C C   . TYR F 1 289 ? 42.655  95.548  35.173  1.00 61.58  ? 289 TYR F C   1 
ATOM   20023 O O   . TYR F 1 289 ? 43.286  95.822  36.192  1.00 62.21  ? 289 TYR F O   1 
ATOM   20024 C CB  . TYR F 1 289 ? 40.146  95.990  35.348  1.00 69.95  ? 289 TYR F CB  1 
ATOM   20025 C CG  . TYR F 1 289 ? 40.046  95.973  36.872  1.00 74.56  ? 289 TYR F CG  1 
ATOM   20026 C CD1 . TYR F 1 289 ? 39.606  97.092  37.574  1.00 70.59  ? 289 TYR F CD1 1 
ATOM   20027 C CD2 . TYR F 1 289 ? 40.365  94.829  37.608  1.00 80.06  ? 289 TYR F CD2 1 
ATOM   20028 C CE1 . TYR F 1 289 ? 39.511  97.085  38.955  1.00 76.87  ? 289 TYR F CE1 1 
ATOM   20029 C CE2 . TYR F 1 289 ? 40.274  94.809  38.991  1.00 82.45  ? 289 TYR F CE2 1 
ATOM   20030 C CZ  . TYR F 1 289 ? 39.849  95.943  39.663  1.00 80.55  ? 289 TYR F CZ  1 
ATOM   20031 O OH  . TYR F 1 289 ? 39.749  95.952  41.020  1.00 71.53  ? 289 TYR F OH  1 
ATOM   20032 N N   . LYS F 1 290 ? 42.904  94.500  34.371  1.00 57.97  ? 290 LYS F N   1 
ATOM   20033 C CA  . LYS F 1 290 ? 43.970  93.542  34.592  1.00 63.21  ? 290 LYS F CA  1 
ATOM   20034 C C   . LYS F 1 290 ? 45.314  94.172  34.217  1.00 70.47  ? 290 LYS F C   1 
ATOM   20035 O O   . LYS F 1 290 ? 46.314  93.985  34.910  1.00 74.02  ? 290 LYS F O   1 
ATOM   20036 C CB  . LYS F 1 290 ? 43.667  92.287  33.765  1.00 67.04  ? 290 LYS F CB  1 
ATOM   20037 C CG  . LYS F 1 290 ? 44.532  91.085  34.104  1.00 79.17  ? 290 LYS F CG  1 
ATOM   20038 C CD  . LYS F 1 290 ? 44.772  90.108  32.956  1.00 87.90  ? 290 LYS F CD  1 
ATOM   20039 C CE  . LYS F 1 290 ? 45.819  89.074  33.276  1.00 89.75  ? 290 LYS F CE  1 
ATOM   20040 N NZ  . LYS F 1 290 ? 46.399  88.519  32.047  1.00 89.98  ? 290 LYS F NZ  1 
ATOM   20041 N N   . LYS F 1 291 ? 45.340  94.937  33.122  1.00 69.30  ? 291 LYS F N   1 
ATOM   20042 C CA  . LYS F 1 291 ? 46.583  95.524  32.648  1.00 68.02  ? 291 LYS F CA  1 
ATOM   20043 C C   . LYS F 1 291 ? 47.133  96.544  33.646  1.00 62.76  ? 291 LYS F C   1 
ATOM   20044 O O   . LYS F 1 291 ? 48.341  96.683  33.772  1.00 65.41  ? 291 LYS F O   1 
ATOM   20045 C CB  . LYS F 1 291 ? 46.423  96.148  31.259  1.00 74.00  ? 291 LYS F CB  1 
ATOM   20046 C CG  . LYS F 1 291 ? 47.704  96.750  30.701  1.00 81.25  ? 291 LYS F CG  1 
ATOM   20047 C CD  . LYS F 1 291 ? 47.910  96.595  29.199  1.00 89.10  ? 291 LYS F CD  1 
ATOM   20048 C CE  . LYS F 1 291 ? 49.245  97.132  28.765  1.00 92.08  ? 291 LYS F CE  1 
ATOM   20049 N NZ  . LYS F 1 291 ? 49.760  96.455  27.572  1.00 95.98  ? 291 LYS F NZ  1 
ATOM   20050 N N   . PHE F 1 292 ? 46.262  97.257  34.359  1.00 59.06  ? 292 PHE F N   1 
ATOM   20051 C CA  . PHE F 1 292 ? 46.707  98.324  35.239  1.00 58.18  ? 292 PHE F CA  1 
ATOM   20052 C C   . PHE F 1 292 ? 46.395  97.981  36.697  1.00 61.88  ? 292 PHE F C   1 
ATOM   20053 O O   . PHE F 1 292 ? 46.485  98.871  37.557  1.00 49.80  ? 292 PHE F O   1 
ATOM   20054 C CB  . PHE F 1 292 ? 46.056  99.615  34.728  1.00 59.22  ? 292 PHE F CB  1 
ATOM   20055 C CG  . PHE F 1 292 ? 46.453  99.993  33.306  1.00 63.91  ? 292 PHE F CG  1 
ATOM   20056 C CD1 . PHE F 1 292 ? 47.791  100.062 32.923  1.00 64.75  ? 292 PHE F CD1 1 
ATOM   20057 C CD2 . PHE F 1 292 ? 45.482  100.237 32.336  1.00 67.85  ? 292 PHE F CD2 1 
ATOM   20058 C CE1 . PHE F 1 292 ? 48.142  100.405 31.623  1.00 64.16  ? 292 PHE F CE1 1 
ATOM   20059 C CE2 . PHE F 1 292 ? 45.837  100.576 31.033  1.00 63.88  ? 292 PHE F CE2 1 
ATOM   20060 C CZ  . PHE F 1 292 ? 47.166  100.656 30.680  1.00 64.81  ? 292 PHE F CZ  1 
ATOM   20061 N N   . GLY F 1 293 ? 46.069  96.687  36.934  1.00 61.54  ? 293 GLY F N   1 
ATOM   20062 C CA  . GLY F 1 293 ? 45.688  96.122  38.226  1.00 54.31  ? 293 GLY F CA  1 
ATOM   20063 C C   . GLY F 1 293 ? 44.715  96.992  39.028  1.00 54.71  ? 293 GLY F C   1 
ATOM   20064 O O   . GLY F 1 293 ? 44.837  97.082  40.245  1.00 58.48  ? 293 GLY F O   1 
ATOM   20065 N N   . GLY F 1 294 ? 43.734  97.621  38.373  1.00 56.04  ? 294 GLY F N   1 
ATOM   20066 C CA  . GLY F 1 294 ? 42.798  98.492  39.071  1.00 54.12  ? 294 GLY F CA  1 
ATOM   20067 C C   . GLY F 1 294 ? 42.332  99.633  38.172  1.00 55.84  ? 294 GLY F C   1 
ATOM   20068 O O   . GLY F 1 294 ? 42.563  99.592  36.965  1.00 67.89  ? 294 GLY F O   1 
ATOM   20069 N N   . VAL F 1 295 ? 41.701  100.658 38.769  1.00 55.44  ? 295 VAL F N   1 
ATOM   20070 C CA  . VAL F 1 295 ? 41.209  101.824 38.037  1.00 57.35  ? 295 VAL F CA  1 
ATOM   20071 C C   . VAL F 1 295 ? 42.394  102.607 37.468  1.00 65.69  ? 295 VAL F C   1 
ATOM   20072 O O   . VAL F 1 295 ? 43.177  103.172 38.228  1.00 69.65  ? 295 VAL F O   1 
ATOM   20073 C CB  . VAL F 1 295 ? 40.298  102.757 38.859  1.00 53.24  ? 295 VAL F CB  1 
ATOM   20074 C CG1 . VAL F 1 295 ? 40.084  104.122 38.208  1.00 52.17  ? 295 VAL F CG1 1 
ATOM   20075 C CG2 . VAL F 1 295 ? 38.954  102.101 39.127  1.00 57.71  ? 295 VAL F CG2 1 
ATOM   20076 N N   . PRO F 1 296 ? 42.508  102.716 36.120  1.00 59.21  ? 296 PRO F N   1 
ATOM   20077 C CA  . PRO F 1 296 ? 43.676  103.321 35.482  1.00 53.60  ? 296 PRO F CA  1 
ATOM   20078 C C   . PRO F 1 296 ? 43.610  104.840 35.497  1.00 48.98  ? 296 PRO F C   1 
ATOM   20079 O O   . PRO F 1 296 ? 42.536  105.409 35.637  1.00 48.13  ? 296 PRO F O   1 
ATOM   20080 C CB  . PRO F 1 296 ? 43.521  102.778 34.063  1.00 56.90  ? 296 PRO F CB  1 
ATOM   20081 C CG  . PRO F 1 296 ? 42.020  102.842 33.835  1.00 57.02  ? 296 PRO F CG  1 
ATOM   20082 C CD  . PRO F 1 296 ? 41.478  102.309 35.145  1.00 57.85  ? 296 PRO F CD  1 
ATOM   20083 N N   . THR F 1 297 ? 44.757  105.488 35.306  1.00 46.09  ? 297 THR F N   1 
ATOM   20084 C CA  . THR F 1 297 ? 44.804  106.930 35.189  1.00 47.53  ? 297 THR F CA  1 
ATOM   20085 C C   . THR F 1 297 ? 44.220  107.311 33.828  1.00 43.74  ? 297 THR F C   1 
ATOM   20086 O O   . THR F 1 297 ? 43.962  106.446 32.995  1.00 39.99  ? 297 THR F O   1 
ATOM   20087 C CB  . THR F 1 297 ? 46.247  107.401 35.396  1.00 56.39  ? 297 THR F CB  1 
ATOM   20088 O OG1 . THR F 1 297 ? 46.207  108.823 35.481  1.00 71.60  ? 297 THR F OG1 1 
ATOM   20089 C CG2 . THR F 1 297 ? 47.179  107.023 34.263  1.00 52.91  ? 297 THR F CG2 1 
ATOM   20090 N N   . LYS F 1 298 ? 43.993  108.606 33.620  1.00 38.45  ? 298 LYS F N   1 
ATOM   20091 C CA  . LYS F 1 298 ? 43.567  109.121 32.339  1.00 44.85  ? 298 LYS F CA  1 
ATOM   20092 C C   . LYS F 1 298 ? 44.550  108.664 31.255  1.00 56.90  ? 298 LYS F C   1 
ATOM   20093 O O   . LYS F 1 298 ? 44.154  108.097 30.231  1.00 56.30  ? 298 LYS F O   1 
ATOM   20094 C CB  . LYS F 1 298 ? 43.451  110.636 32.524  1.00 54.44  ? 298 LYS F CB  1 
ATOM   20095 C CG  . LYS F 1 298 ? 42.555  111.417 31.564  1.00 62.14  ? 298 LYS F CG  1 
ATOM   20096 C CD  . LYS F 1 298 ? 43.216  111.820 30.251  1.00 71.83  ? 298 LYS F CD  1 
ATOM   20097 C CE  . LYS F 1 298 ? 42.371  112.753 29.412  1.00 78.93  ? 298 LYS F CE  1 
ATOM   20098 N NZ  . LYS F 1 298 ? 42.149  114.063 30.034  1.00 80.70  ? 298 LYS F NZ  1 
ATOM   20099 N N   . GLU F 1 299 ? 45.847  108.858 31.521  1.00 60.47  ? 299 GLU F N   1 
ATOM   20100 C CA  . GLU F 1 299 ? 46.912  108.527 30.587  1.00 56.27  ? 299 GLU F CA  1 
ATOM   20101 C C   . GLU F 1 299 ? 46.882  107.034 30.233  1.00 47.84  ? 299 GLU F C   1 
ATOM   20102 O O   . GLU F 1 299 ? 46.931  106.675 29.063  1.00 44.34  ? 299 GLU F O   1 
ATOM   20103 C CB  . GLU F 1 299 ? 48.203  109.079 31.208  1.00 70.88  ? 299 GLU F CB  1 
ATOM   20104 C CG  . GLU F 1 299 ? 49.420  109.118 30.283  1.00 77.59  ? 299 GLU F CG  1 
ATOM   20105 C CD  . GLU F 1 299 ? 50.114  107.781 30.036  1.00 81.20  ? 299 GLU F CD  1 
ATOM   20106 O OE1 . GLU F 1 299 ? 50.303  107.007 31.014  1.00 76.91  ? 299 GLU F OE1 1 
ATOM   20107 O OE2 . GLU F 1 299 ? 50.484  107.520 28.862  1.00 83.04  ? 299 GLU F OE2 1 
ATOM   20108 N N   . GLN F 1 300 ? 46.771  106.147 31.223  1.00 43.14  ? 300 GLN F N   1 
ATOM   20109 C CA  . GLN F 1 300 ? 46.741  104.714 30.967  1.00 42.69  ? 300 GLN F CA  1 
ATOM   20110 C C   . GLN F 1 300 ? 45.539  104.262 30.121  1.00 49.14  ? 300 GLN F C   1 
ATOM   20111 O O   . GLN F 1 300 ? 45.659  103.313 29.350  1.00 51.29  ? 300 GLN F O   1 
ATOM   20112 C CB  . GLN F 1 300 ? 46.732  103.991 32.307  1.00 43.91  ? 300 GLN F CB  1 
ATOM   20113 C CG  . GLN F 1 300 ? 48.068  104.069 33.034  1.00 51.17  ? 300 GLN F CG  1 
ATOM   20114 C CD  . GLN F 1 300 ? 48.032  103.378 34.372  1.00 53.95  ? 300 GLN F CD  1 
ATOM   20115 O OE1 . GLN F 1 300 ? 48.758  102.411 34.630  1.00 55.00  ? 300 GLN F OE1 1 
ATOM   20116 N NE2 . GLN F 1 300 ? 47.139  103.850 35.221  1.00 56.41  ? 300 GLN F NE2 1 
ATOM   20117 N N   . LEU F 1 301 ? 44.373  104.904 30.291  1.00 47.23  ? 301 LEU F N   1 
ATOM   20118 C CA  . LEU F 1 301 ? 43.153  104.582 29.560  1.00 47.85  ? 301 LEU F CA  1 
ATOM   20119 C C   . LEU F 1 301 ? 43.287  105.078 28.117  1.00 46.50  ? 301 LEU F C   1 
ATOM   20120 O O   . LEU F 1 301 ? 42.838  104.418 27.172  1.00 35.52  ? 301 LEU F O   1 
ATOM   20121 C CB  . LEU F 1 301 ? 41.989  105.295 30.252  1.00 47.70  ? 301 LEU F CB  1 
ATOM   20122 C CG  . LEU F 1 301 ? 40.573  104.721 30.125  1.00 48.13  ? 301 LEU F CG  1 
ATOM   20123 C CD1 . LEU F 1 301 ? 39.590  105.878 30.038  1.00 44.82  ? 301 LEU F CD1 1 
ATOM   20124 C CD2 . LEU F 1 301 ? 40.340  103.768 28.992  1.00 52.26  ? 301 LEU F CD2 1 
ATOM   20125 N N   . GLU F 1 302 ? 43.873  106.278 28.000  1.00 38.86  ? 302 GLU F N   1 
ATOM   20126 C CA  . GLU F 1 302 ? 44.166  106.910 26.732  1.00 37.70  ? 302 GLU F CA  1 
ATOM   20127 C C   . GLU F 1 302 ? 45.007  105.927 25.921  1.00 40.29  ? 302 GLU F C   1 
ATOM   20128 O O   . GLU F 1 302 ? 44.623  105.498 24.837  1.00 38.49  ? 302 GLU F O   1 
ATOM   20129 C CB  . GLU F 1 302 ? 44.839  108.252 27.040  1.00 39.03  ? 302 GLU F CB  1 
ATOM   20130 C CG  . GLU F 1 302 ? 44.447  109.402 26.116  1.00 44.74  ? 302 GLU F CG  1 
ATOM   20131 C CD  . GLU F 1 302 ? 44.365  110.785 26.770  1.00 48.81  ? 302 GLU F CD  1 
ATOM   20132 O OE1 . GLU F 1 302 ? 45.406  111.367 27.117  1.00 48.41  ? 302 GLU F OE1 1 
ATOM   20133 O OE2 . GLU F 1 302 ? 43.243  111.309 26.939  1.00 51.48  ? 302 GLU F OE2 1 
ATOM   20134 N N   . ARG F 1 303 ? 46.120  105.500 26.513  1.00 40.81  ? 303 ARG F N   1 
ATOM   20135 C CA  . ARG F 1 303 ? 47.061  104.610 25.862  1.00 46.47  ? 303 ARG F CA  1 
ATOM   20136 C C   . ARG F 1 303 ? 46.334  103.334 25.441  1.00 44.87  ? 303 ARG F C   1 
ATOM   20137 O O   . ARG F 1 303 ? 46.619  102.798 24.365  1.00 46.61  ? 303 ARG F O   1 
ATOM   20138 C CB  . ARG F 1 303 ? 48.246  104.356 26.812  1.00 55.28  ? 303 ARG F CB  1 
ATOM   20139 C CG  . ARG F 1 303 ? 49.572  103.920 26.203  1.00 64.37  ? 303 ARG F CG  1 
ATOM   20140 C CD  . ARG F 1 303 ? 50.748  104.175 27.151  1.00 68.79  ? 303 ARG F CD  1 
ATOM   20141 N NE  . ARG F 1 303 ? 50.949  103.104 28.141  1.00 75.04  ? 303 ARG F NE  1 
ATOM   20142 C CZ  . ARG F 1 303 ? 51.013  103.229 29.479  1.00 69.57  ? 303 ARG F CZ  1 
ATOM   20143 N NH1 . ARG F 1 303 ? 51.300  102.175 30.229  1.00 65.41  ? 303 ARG F NH1 1 
ATOM   20144 N NH2 . ARG F 1 303 ? 50.821  104.398 30.072  1.00 63.27  ? 303 ARG F NH2 1 
ATOM   20145 N N   . PHE F 1 304 ? 45.407  102.868 26.297  1.00 39.35  ? 304 PHE F N   1 
ATOM   20146 C CA  . PHE F 1 304 ? 44.717  101.600 26.094  1.00 36.87  ? 304 PHE F CA  1 
ATOM   20147 C C   . PHE F 1 304 ? 43.698  101.706 24.954  1.00 34.44  ? 304 PHE F C   1 
ATOM   20148 O O   . PHE F 1 304 ? 43.561  100.785 24.164  1.00 35.47  ? 304 PHE F O   1 
ATOM   20149 C CB  . PHE F 1 304 ? 44.031  101.103 27.369  1.00 37.42  ? 304 PHE F CB  1 
ATOM   20150 C CG  . PHE F 1 304 ? 43.565  99.662  27.248  1.00 37.97  ? 304 PHE F CG  1 
ATOM   20151 C CD1 . PHE F 1 304 ? 44.485  98.622  27.213  1.00 41.16  ? 304 PHE F CD1 1 
ATOM   20152 C CD2 . PHE F 1 304 ? 42.214  99.355  27.124  1.00 41.11  ? 304 PHE F CD2 1 
ATOM   20153 C CE1 . PHE F 1 304 ? 44.068  97.305  27.063  1.00 42.84  ? 304 PHE F CE1 1 
ATOM   20154 C CE2 . PHE F 1 304 ? 41.793  98.035  26.984  1.00 41.35  ? 304 PHE F CE2 1 
ATOM   20155 C CZ  . PHE F 1 304 ? 42.720  97.011  26.960  1.00 42.97  ? 304 PHE F CZ  1 
ATOM   20156 N N   . ALA F 1 305 ? 42.957  102.808 24.889  1.00 32.71  ? 305 ALA F N   1 
ATOM   20157 C CA  . ALA F 1 305 ? 42.022  103.045 23.807  1.00 30.71  ? 305 ALA F CA  1 
ATOM   20158 C C   . ALA F 1 305 ? 42.768  102.980 22.476  1.00 33.27  ? 305 ALA F C   1 
ATOM   20159 O O   . ALA F 1 305 ? 42.350  102.245 21.576  1.00 37.88  ? 305 ALA F O   1 
ATOM   20160 C CB  . ALA F 1 305 ? 41.355  104.392 24.004  1.00 28.54  ? 305 ALA F CB  1 
ATOM   20161 N N   . TRP F 1 306 ? 43.859  103.766 22.384  1.00 30.50  ? 306 TRP F N   1 
ATOM   20162 C CA  . TRP F 1 306 ? 44.680  103.904 21.187  1.00 30.74  ? 306 TRP F CA  1 
ATOM   20163 C C   . TRP F 1 306 ? 45.261  102.556 20.748  1.00 27.78  ? 306 TRP F C   1 
ATOM   20164 O O   . TRP F 1 306 ? 45.236  102.251 19.560  1.00 26.00  ? 306 TRP F O   1 
ATOM   20165 C CB  . TRP F 1 306 ? 45.782  104.954 21.413  1.00 30.79  ? 306 TRP F CB  1 
ATOM   20166 C CG  . TRP F 1 306 ? 45.293  106.383 21.379  1.00 31.52  ? 306 TRP F CG  1 
ATOM   20167 C CD1 . TRP F 1 306 ? 45.161  107.272 22.411  1.00 31.90  ? 306 TRP F CD1 1 
ATOM   20168 C CD2 . TRP F 1 306 ? 44.898  107.096 20.193  1.00 30.50  ? 306 TRP F CD2 1 
ATOM   20169 N NE1 . TRP F 1 306 ? 44.687  108.472 21.947  1.00 33.25  ? 306 TRP F NE1 1 
ATOM   20170 C CE2 . TRP F 1 306 ? 44.533  108.399 20.594  1.00 33.45  ? 306 TRP F CE2 1 
ATOM   20171 C CE3 . TRP F 1 306 ? 44.826  106.754 18.837  1.00 31.58  ? 306 TRP F CE3 1 
ATOM   20172 C CZ2 . TRP F 1 306 ? 44.103  109.359 19.678  1.00 39.73  ? 306 TRP F CZ2 1 
ATOM   20173 C CZ3 . TRP F 1 306 ? 44.426  107.709 17.928  1.00 33.13  ? 306 TRP F CZ3 1 
ATOM   20174 C CH2 . TRP F 1 306 ? 44.060  108.993 18.343  1.00 35.58  ? 306 TRP F CH2 1 
ATOM   20175 N N   . ASP F 1 307 ? 45.716  101.733 21.704  1.00 27.04  ? 307 ASP F N   1 
ATOM   20176 C CA  . ASP F 1 307 ? 46.245  100.415 21.387  1.00 33.28  ? 307 ASP F CA  1 
ATOM   20177 C C   . ASP F 1 307 ? 45.173  99.503  20.808  1.00 32.49  ? 307 ASP F C   1 
ATOM   20178 O O   . ASP F 1 307 ? 45.504  98.657  19.987  1.00 33.22  ? 307 ASP F O   1 
ATOM   20179 C CB  . ASP F 1 307 ? 46.839  99.658  22.564  1.00 35.95  ? 307 ASP F CB  1 
ATOM   20180 C CG  . ASP F 1 307 ? 48.137  100.232 23.097  1.00 42.88  ? 307 ASP F CG  1 
ATOM   20181 O OD1 . ASP F 1 307 ? 48.660  101.190 22.469  1.00 42.93  ? 307 ASP F OD1 1 
ATOM   20182 O OD2 . ASP F 1 307 ? 48.575  99.753  24.161  1.00 47.43  ? 307 ASP F OD2 1 
ATOM   20183 N N   . THR F 1 308 ? 43.917  99.644  21.246  1.00 31.03  ? 308 THR F N   1 
ATOM   20184 C CA  . THR F 1 308 ? 42.852  98.856  20.641  1.00 32.21  ? 308 THR F CA  1 
ATOM   20185 C C   . THR F 1 308 ? 42.526  99.418  19.247  1.00 32.54  ? 308 THR F C   1 
ATOM   20186 O O   . THR F 1 308 ? 42.404  98.649  18.290  1.00 28.73  ? 308 THR F O   1 
ATOM   20187 C CB  . THR F 1 308 ? 41.669  98.664  21.592  1.00 31.66  ? 308 THR F CB  1 
ATOM   20188 O OG1 . THR F 1 308 ? 40.476  98.890  20.855  1.00 41.63  ? 308 THR F OG1 1 
ATOM   20189 C CG2 . THR F 1 308 ? 41.655  99.621  22.752  1.00 30.12  ? 308 THR F CG2 1 
ATOM   20190 N N   . LEU F 1 309 ? 42.533  100.747 19.084  1.00 31.96  ? 309 LEU F N   1 
ATOM   20191 C CA  . LEU F 1 309 ? 42.294  101.340 17.775  1.00 35.20  ? 309 LEU F CA  1 
ATOM   20192 C C   . LEU F 1 309 ? 43.376  100.924 16.786  1.00 35.88  ? 309 LEU F C   1 
ATOM   20193 O O   . LEU F 1 309 ? 43.064  100.546 15.661  1.00 31.13  ? 309 LEU F O   1 
ATOM   20194 C CB  . LEU F 1 309 ? 42.192  102.861 17.852  1.00 35.48  ? 309 LEU F CB  1 
ATOM   20195 C CG  . LEU F 1 309 ? 40.995  103.396 18.643  1.00 35.00  ? 309 LEU F CG  1 
ATOM   20196 C CD1 . LEU F 1 309 ? 41.161  104.843 18.994  1.00 32.25  ? 309 LEU F CD1 1 
ATOM   20197 C CD2 . LEU F 1 309 ? 39.726  103.209 17.831  1.00 39.45  ? 309 LEU F CD2 1 
ATOM   20198 N N   . ASN F 1 310 ? 44.640  100.985 17.228  1.00 40.15  ? 310 ASN F N   1 
ATOM   20199 C CA  . ASN F 1 310 ? 45.794  100.733 16.364  1.00 34.88  ? 310 ASN F CA  1 
ATOM   20200 C C   . ASN F 1 310 ? 45.925  99.257  16.001  1.00 34.45  ? 310 ASN F C   1 
ATOM   20201 O O   . ASN F 1 310 ? 46.545  98.904  14.994  1.00 33.09  ? 310 ASN F O   1 
ATOM   20202 C CB  . ASN F 1 310 ? 47.101  101.180 17.004  1.00 33.53  ? 310 ASN F CB  1 
ATOM   20203 C CG  . ASN F 1 310 ? 47.224  102.682 17.046  1.00 33.73  ? 310 ASN F CG  1 
ATOM   20204 O OD1 . ASN F 1 310 ? 46.841  103.355 16.083  1.00 32.00  ? 310 ASN F OD1 1 
ATOM   20205 N ND2 . ASN F 1 310 ? 47.751  103.216 18.141  1.00 36.58  ? 310 ASN F ND2 1 
ATOM   20206 N N   . SER F 1 311 ? 45.333  98.384  16.817  1.00 36.04  ? 311 SER F N   1 
ATOM   20207 C CA  . SER F 1 311 ? 45.360  96.964  16.526  1.00 35.47  ? 311 SER F CA  1 
ATOM   20208 C C   . SER F 1 311 ? 44.181  96.602  15.616  1.00 33.74  ? 311 SER F C   1 
ATOM   20209 O O   . SER F 1 311 ? 43.921  95.422  15.417  1.00 38.06  ? 311 SER F O   1 
ATOM   20210 C CB  . SER F 1 311 ? 45.359  96.156  17.803  1.00 32.43  ? 311 SER F CB  1 
ATOM   20211 O OG  . SER F 1 311 ? 44.040  96.059  18.313  1.00 31.82  ? 311 SER F OG  1 
ATOM   20212 N N   . GLY F 1 312 ? 43.444  97.608  15.117  1.00 29.48  ? 312 GLY F N   1 
ATOM   20213 C CA  . GLY F 1 312 ? 42.371  97.387  14.163  1.00 29.91  ? 312 GLY F CA  1 
ATOM   20214 C C   . GLY F 1 312 ? 41.104  96.820  14.811  1.00 32.68  ? 312 GLY F C   1 
ATOM   20215 O O   . GLY F 1 312 ? 40.303  96.156  14.153  1.00 34.80  ? 312 GLY F O   1 
ATOM   20216 N N   . GLN F 1 313 ? 40.901  97.121  16.096  1.00 32.18  ? 313 GLN F N   1 
ATOM   20217 C CA  . GLN F 1 313 ? 39.716  96.695  16.821  1.00 33.25  ? 313 GLN F CA  1 
ATOM   20218 C C   . GLN F 1 313 ? 38.834  97.899  17.118  1.00 29.87  ? 313 GLN F C   1 
ATOM   20219 O O   . GLN F 1 313 ? 39.298  99.030  17.246  1.00 26.74  ? 313 GLN F O   1 
ATOM   20220 C CB  . GLN F 1 313 ? 40.047  96.052  18.166  1.00 38.42  ? 313 GLN F CB  1 
ATOM   20221 C CG  . GLN F 1 313 ? 40.835  94.751  18.067  1.00 41.08  ? 313 GLN F CG  1 
ATOM   20222 C CD  . GLN F 1 313 ? 40.013  93.604  17.522  1.00 45.43  ? 313 GLN F CD  1 
ATOM   20223 O OE1 . GLN F 1 313 ? 38.914  93.314  18.008  1.00 48.85  ? 313 GLN F OE1 1 
ATOM   20224 N NE2 . GLN F 1 313 ? 40.549  92.936  16.511  1.00 49.96  ? 313 GLN F NE2 1 
ATOM   20225 N N   . VAL F 1 314 ? 37.552  97.618  17.303  1.00 30.00  ? 314 VAL F N   1 
ATOM   20226 C CA  . VAL F 1 314 ? 36.592  98.645  17.683  1.00 31.47  ? 314 VAL F CA  1 
ATOM   20227 C C   . VAL F 1 314 ? 36.642  98.860  19.204  1.00 28.40  ? 314 VAL F C   1 
ATOM   20228 O O   . VAL F 1 314 ? 37.002  97.940  19.927  1.00 27.52  ? 314 VAL F O   1 
ATOM   20229 C CB  . VAL F 1 314 ? 35.309  98.032  17.078  1.00 33.48  ? 314 VAL F CB  1 
ATOM   20230 C CG1 . VAL F 1 314 ? 34.199  97.791  18.085  1.00 36.80  ? 314 VAL F CG1 1 
ATOM   20231 C CG2 . VAL F 1 314 ? 34.840  98.820  15.856  1.00 32.79  ? 314 VAL F CG2 1 
ATOM   20232 N N   . ILE F 1 315 ? 36.404  100.086 19.704  1.00 28.73  ? 315 ILE F N   1 
ATOM   20233 C CA  . ILE F 1 315 ? 36.207  100.315 21.133  1.00 27.85  ? 315 ILE F CA  1 
ATOM   20234 C C   . ILE F 1 315 ? 34.726  100.095 21.433  1.00 28.77  ? 315 ILE F C   1 
ATOM   20235 O O   . ILE F 1 315 ? 33.928  100.985 21.134  1.00 27.79  ? 315 ILE F O   1 
ATOM   20236 C CB  . ILE F 1 315 ? 36.604  101.749 21.548  1.00 30.56  ? 315 ILE F CB  1 
ATOM   20237 C CG1 . ILE F 1 315 ? 38.098  101.996 21.457  1.00 32.49  ? 315 ILE F CG1 1 
ATOM   20238 C CG2 . ILE F 1 315 ? 36.081  102.101 22.950  1.00 31.74  ? 315 ILE F CG2 1 
ATOM   20239 C CD1 . ILE F 1 315 ? 38.482  103.454 21.691  1.00 31.93  ? 315 ILE F CD1 1 
ATOM   20240 N N   . PRO F 1 316 ? 34.290  98.967  22.047  1.00 28.04  ? 316 PRO F N   1 
ATOM   20241 C CA  . PRO F 1 316 ? 32.861  98.686  22.206  1.00 27.54  ? 316 PRO F CA  1 
ATOM   20242 C C   . PRO F 1 316 ? 32.183  99.747  23.060  1.00 28.71  ? 316 PRO F C   1 
ATOM   20243 O O   . PRO F 1 316 ? 32.825  100.295 23.964  1.00 30.24  ? 316 PRO F O   1 
ATOM   20244 C CB  . PRO F 1 316 ? 32.770  97.293  22.847  1.00 27.86  ? 316 PRO F CB  1 
ATOM   20245 C CG  . PRO F 1 316 ? 34.143  96.689  22.621  1.00 29.07  ? 316 PRO F CG  1 
ATOM   20246 C CD  . PRO F 1 316 ? 35.110  97.895  22.607  1.00 28.85  ? 316 PRO F CD  1 
ATOM   20247 N N   . GLY F 1 317 ? 30.898  100.015 22.735  1.00 25.53  ? 317 GLY F N   1 
ATOM   20248 C CA  . GLY F 1 317 ? 30.013  100.839 23.540  1.00 23.32  ? 317 GLY F CA  1 
ATOM   20249 C C   . GLY F 1 317 ? 29.988  102.299 23.103  1.00 25.12  ? 317 GLY F C   1 
ATOM   20250 O O   . GLY F 1 317 ? 29.275  103.118 23.682  1.00 26.56  ? 317 GLY F O   1 
ATOM   20251 N N   . TYR F 1 318 ? 30.777  102.634 22.080  1.00 27.93  ? 318 TYR F N   1 
ATOM   20252 C CA  . TYR F 1 318 ? 30.809  103.974 21.522  1.00 28.57  ? 318 TYR F CA  1 
ATOM   20253 C C   . TYR F 1 318 ? 30.481  103.911 20.032  1.00 31.91  ? 318 TYR F C   1 
ATOM   20254 O O   . TYR F 1 318 ? 30.814  102.947 19.330  1.00 31.39  ? 318 TYR F O   1 
ATOM   20255 C CB  . TYR F 1 318 ? 32.196  104.545 21.827  1.00 30.13  ? 318 TYR F CB  1 
ATOM   20256 C CG  . TYR F 1 318 ? 32.361  104.817 23.310  1.00 33.85  ? 318 TYR F CG  1 
ATOM   20257 C CD1 . TYR F 1 318 ? 32.638  103.781 24.193  1.00 32.03  ? 318 TYR F CD1 1 
ATOM   20258 C CD2 . TYR F 1 318 ? 32.189  106.104 23.826  1.00 34.99  ? 318 TYR F CD2 1 
ATOM   20259 C CE1 . TYR F 1 318 ? 32.744  104.014 25.553  1.00 33.73  ? 318 TYR F CE1 1 
ATOM   20260 C CE2 . TYR F 1 318 ? 32.320  106.347 25.184  1.00 34.67  ? 318 TYR F CE2 1 
ATOM   20261 C CZ  . TYR F 1 318 ? 32.593  105.297 26.048  1.00 35.32  ? 318 TYR F CZ  1 
ATOM   20262 O OH  . TYR F 1 318 ? 32.726  105.501 27.399  1.00 43.76  ? 318 TYR F OH  1 
ATOM   20263 N N   . GLY F 1 319 ? 29.843  104.970 19.546  1.00 30.80  ? 319 GLY F N   1 
ATOM   20264 C CA  . GLY F 1 319 ? 29.469  105.010 18.154  1.00 32.89  ? 319 GLY F CA  1 
ATOM   20265 C C   . GLY F 1 319 ? 28.012  104.598 17.990  1.00 36.12  ? 319 GLY F C   1 
ATOM   20266 O O   . GLY F 1 319 ? 27.415  103.984 18.877  1.00 34.76  ? 319 GLY F O   1 
ATOM   20267 N N   . HIS F 1 320 ? 27.455  104.980 16.838  1.00 36.46  ? 320 HIS F N   1 
ATOM   20268 C CA  . HIS F 1 320 ? 26.096  104.635 16.479  1.00 35.22  ? 320 HIS F CA  1 
ATOM   20269 C C   . HIS F 1 320 ? 25.863  104.970 15.010  1.00 36.93  ? 320 HIS F C   1 
ATOM   20270 O O   . HIS F 1 320 ? 26.532  105.840 14.473  1.00 36.98  ? 320 HIS F O   1 
ATOM   20271 C CB  . HIS F 1 320 ? 25.090  105.382 17.348  1.00 32.41  ? 320 HIS F CB  1 
ATOM   20272 C CG  . HIS F 1 320 ? 23.846  104.596 17.376  1.00 32.55  ? 320 HIS F CG  1 
ATOM   20273 N ND1 . HIS F 1 320 ? 22.781  104.900 16.573  1.00 31.46  ? 320 HIS F ND1 1 
ATOM   20274 C CD2 . HIS F 1 320 ? 23.537  103.464 18.011  1.00 30.15  ? 320 HIS F CD2 1 
ATOM   20275 C CE1 . HIS F 1 320 ? 21.830  104.001 16.780  1.00 33.90  ? 320 HIS F CE1 1 
ATOM   20276 N NE2 . HIS F 1 320 ? 22.277  103.113 17.639  1.00 30.08  ? 320 HIS F NE2 1 
ATOM   20277 N N   . ALA F 1 321 ? 24.910  104.280 14.378  1.00 37.19  ? 321 ALA F N   1 
ATOM   20278 C CA  . ALA F 1 321 ? 24.662  104.462 12.957  1.00 37.28  ? 321 ALA F CA  1 
ATOM   20279 C C   . ALA F 1 321 ? 23.817  105.713 12.698  1.00 35.80  ? 321 ALA F C   1 
ATOM   20280 O O   . ALA F 1 321 ? 23.880  106.300 11.607  1.00 35.46  ? 321 ALA F O   1 
ATOM   20281 C CB  . ALA F 1 321 ? 24.014  103.226 12.388  1.00 36.83  ? 321 ALA F CB  1 
ATOM   20282 N N   . VAL F 1 322 ? 23.024  106.125 13.693  1.00 33.26  ? 322 VAL F N   1 
ATOM   20283 C CA  . VAL F 1 322 ? 22.236  107.336 13.542  1.00 33.13  ? 322 VAL F CA  1 
ATOM   20284 C C   . VAL F 1 322 ? 22.533  108.339 14.666  1.00 33.82  ? 322 VAL F C   1 
ATOM   20285 O O   . VAL F 1 322 ? 22.654  109.525 14.373  1.00 34.48  ? 322 VAL F O   1 
ATOM   20286 C CB  . VAL F 1 322 ? 20.731  107.081 13.275  1.00 30.83  ? 322 VAL F CB  1 
ATOM   20287 C CG1 . VAL F 1 322 ? 20.343  105.618 13.329  1.00 30.49  ? 322 VAL F CG1 1 
ATOM   20288 C CG2 . VAL F 1 322 ? 19.795  107.977 14.082  1.00 34.47  ? 322 VAL F CG2 1 
ATOM   20289 N N   . LEU F 1 323 ? 22.618  107.879 15.924  1.00 36.26  ? 323 LEU F N   1 
ATOM   20290 C CA  . LEU F 1 323 ? 22.942  108.714 17.076  1.00 37.35  ? 323 LEU F CA  1 
ATOM   20291 C C   . LEU F 1 323 ? 24.184  109.561 16.771  1.00 38.90  ? 323 LEU F C   1 
ATOM   20292 O O   . LEU F 1 323 ? 25.168  109.031 16.258  1.00 37.87  ? 323 LEU F O   1 
ATOM   20293 C CB  . LEU F 1 323 ? 23.196  107.797 18.279  1.00 40.20  ? 323 LEU F CB  1 
ATOM   20294 C CG  . LEU F 1 323 ? 22.252  107.811 19.495  1.00 41.55  ? 323 LEU F CG  1 
ATOM   20295 C CD1 . LEU F 1 323 ? 21.336  109.009 19.566  1.00 40.32  ? 323 LEU F CD1 1 
ATOM   20296 C CD2 . LEU F 1 323 ? 21.452  106.542 19.673  1.00 43.17  ? 323 LEU F CD2 1 
ATOM   20297 N N   . ARG F 1 324 ? 24.143  110.872 17.068  1.00 35.41  ? 324 ARG F N   1 
ATOM   20298 C CA  . ARG F 1 324 ? 25.336  111.709 16.963  1.00 37.77  ? 324 ARG F CA  1 
ATOM   20299 C C   . ARG F 1 324 ? 25.565  112.423 18.294  1.00 38.49  ? 324 ARG F C   1 
ATOM   20300 O O   . ARG F 1 324 ? 26.201  113.478 18.318  1.00 38.76  ? 324 ARG F O   1 
ATOM   20301 C CB  . ARG F 1 324 ? 25.274  112.745 15.826  1.00 38.45  ? 324 ARG F CB  1 
ATOM   20302 C CG  . ARG F 1 324 ? 25.107  112.184 14.413  1.00 38.69  ? 324 ARG F CG  1 
ATOM   20303 C CD  . ARG F 1 324 ? 26.387  111.589 13.830  1.00 37.51  ? 324 ARG F CD  1 
ATOM   20304 N NE  . ARG F 1 324 ? 26.244  110.828 12.578  1.00 38.63  ? 324 ARG F NE  1 
ATOM   20305 C CZ  . ARG F 1 324 ? 26.250  109.492 12.469  1.00 41.00  ? 324 ARG F CZ  1 
ATOM   20306 N NH1 . ARG F 1 324 ? 26.320  108.899 11.288  1.00 42.63  ? 324 ARG F NH1 1 
ATOM   20307 N NH2 . ARG F 1 324 ? 26.219  108.728 13.548  1.00 43.99  ? 324 ARG F NH2 1 
ATOM   20308 N N   . VAL F 1 325 ? 25.035  111.835 19.382  1.00 34.99  ? 325 VAL F N   1 
ATOM   20309 C CA  . VAL F 1 325 ? 25.072  112.405 20.723  1.00 34.68  ? 325 VAL F CA  1 
ATOM   20310 C C   . VAL F 1 325 ? 24.983  111.258 21.723  1.00 32.80  ? 325 VAL F C   1 
ATOM   20311 O O   . VAL F 1 325 ? 24.620  110.133 21.375  1.00 32.25  ? 325 VAL F O   1 
ATOM   20312 C CB  . VAL F 1 325 ? 23.986  113.451 21.055  1.00 37.02  ? 325 VAL F CB  1 
ATOM   20313 C CG1 . VAL F 1 325 ? 24.096  114.700 20.191  1.00 37.96  ? 325 VAL F CG1 1 
ATOM   20314 C CG2 . VAL F 1 325 ? 22.572  112.890 20.970  1.00 38.81  ? 325 VAL F CG2 1 
ATOM   20315 N N   . THR F 1 326 ? 25.345  111.563 22.969  1.00 31.27  ? 326 THR F N   1 
ATOM   20316 C CA  . THR F 1 326 ? 25.259  110.591 24.036  1.00 30.96  ? 326 THR F CA  1 
ATOM   20317 C C   . THR F 1 326 ? 23.831  110.023 24.018  1.00 32.89  ? 326 THR F C   1 
ATOM   20318 O O   . THR F 1 326 ? 22.862  110.782 23.902  1.00 32.42  ? 326 THR F O   1 
ATOM   20319 C CB  . THR F 1 326 ? 25.665  111.286 25.338  1.00 31.71  ? 326 THR F CB  1 
ATOM   20320 O OG1 . THR F 1 326 ? 27.069  111.554 25.260  1.00 28.39  ? 326 THR F OG1 1 
ATOM   20321 C CG2 . THR F 1 326 ? 25.407  110.423 26.560  1.00 31.76  ? 326 THR F CG2 1 
ATOM   20322 N N   . ASP F 1 327 ? 23.729  108.679 24.079  1.00 30.55  ? 327 ASP F N   1 
ATOM   20323 C CA  . ASP F 1 327 ? 22.490  107.913 23.942  1.00 27.33  ? 327 ASP F CA  1 
ATOM   20324 C C   . ASP F 1 327 ? 21.635  108.072 25.195  1.00 27.24  ? 327 ASP F C   1 
ATOM   20325 O O   . ASP F 1 327 ? 22.046  107.776 26.307  1.00 23.90  ? 327 ASP F O   1 
ATOM   20326 C CB  . ASP F 1 327 ? 22.840  106.453 23.703  1.00 27.04  ? 327 ASP F CB  1 
ATOM   20327 C CG  . ASP F 1 327 ? 21.732  105.454 23.399  1.00 29.45  ? 327 ASP F CG  1 
ATOM   20328 O OD1 . ASP F 1 327 ? 20.513  105.788 23.450  1.00 27.08  ? 327 ASP F OD1 1 
ATOM   20329 O OD2 . ASP F 1 327 ? 22.119  104.310 23.101  1.00 33.08  ? 327 ASP F OD2 1 
ATOM   20330 N N   . PRO F 1 328 ? 20.383  108.532 25.080  1.00 29.32  ? 328 PRO F N   1 
ATOM   20331 C CA  . PRO F 1 328 ? 19.561  108.705 26.267  1.00 27.86  ? 328 PRO F CA  1 
ATOM   20332 C C   . PRO F 1 328 ? 19.290  107.417 27.029  1.00 28.53  ? 328 PRO F C   1 
ATOM   20333 O O   . PRO F 1 328 ? 18.881  107.478 28.182  1.00 28.45  ? 328 PRO F O   1 
ATOM   20334 C CB  . PRO F 1 328 ? 18.294  109.378 25.773  1.00 29.77  ? 328 PRO F CB  1 
ATOM   20335 C CG  . PRO F 1 328 ? 18.288  109.174 24.272  1.00 31.83  ? 328 PRO F CG  1 
ATOM   20336 C CD  . PRO F 1 328 ? 19.735  108.969 23.837  1.00 30.58  ? 328 PRO F CD  1 
ATOM   20337 N N   . ARG F 1 329 ? 19.564  106.259 26.415  1.00 30.24  ? 329 ARG F N   1 
ATOM   20338 C CA  . ARG F 1 329 ? 19.419  104.986 27.107  1.00 28.71  ? 329 ARG F CA  1 
ATOM   20339 C C   . ARG F 1 329 ? 20.621  104.831 28.021  1.00 31.09  ? 329 ARG F C   1 
ATOM   20340 O O   . ARG F 1 329 ? 20.543  104.157 29.059  1.00 35.65  ? 329 ARG F O   1 
ATOM   20341 C CB  . ARG F 1 329 ? 19.333  103.804 26.131  1.00 29.79  ? 329 ARG F CB  1 
ATOM   20342 C CG  . ARG F 1 329 ? 18.110  103.798 25.222  1.00 29.18  ? 329 ARG F CG  1 
ATOM   20343 C CD  . ARG F 1 329 ? 18.176  102.715 24.168  1.00 28.29  ? 329 ARG F CD  1 
ATOM   20344 N NE  . ARG F 1 329 ? 19.230  102.934 23.179  1.00 29.61  ? 329 ARG F NE  1 
ATOM   20345 C CZ  . ARG F 1 329 ? 19.558  102.078 22.195  1.00 33.51  ? 329 ARG F CZ  1 
ATOM   20346 N NH1 . ARG F 1 329 ? 18.936  100.923 22.014  1.00 33.90  ? 329 ARG F NH1 1 
ATOM   20347 N NH2 . ARG F 1 329 ? 20.556  102.371 21.379  1.00 37.63  ? 329 ARG F NH2 1 
ATOM   20348 N N   . TYR F 1 330 ? 21.735  105.443 27.591  1.00 29.44  ? 330 TYR F N   1 
ATOM   20349 C CA  . TYR F 1 330 ? 22.938  105.549 28.409  1.00 29.76  ? 330 TYR F CA  1 
ATOM   20350 C C   . TYR F 1 330 ? 22.698  106.467 29.604  1.00 28.96  ? 330 TYR F C   1 
ATOM   20351 O O   . TYR F 1 330 ? 22.906  106.066 30.744  1.00 33.08  ? 330 TYR F O   1 
ATOM   20352 C CB  . TYR F 1 330 ? 24.123  106.096 27.607  1.00 30.82  ? 330 TYR F CB  1 
ATOM   20353 C CG  . TYR F 1 330 ? 25.450  106.188 28.349  1.00 29.48  ? 330 TYR F CG  1 
ATOM   20354 C CD1 . TYR F 1 330 ? 26.305  105.098 28.412  1.00 30.64  ? 330 TYR F CD1 1 
ATOM   20355 C CD2 . TYR F 1 330 ? 25.846  107.364 28.983  1.00 29.04  ? 330 TYR F CD2 1 
ATOM   20356 C CE1 . TYR F 1 330 ? 27.518  105.177 29.086  1.00 33.44  ? 330 TYR F CE1 1 
ATOM   20357 C CE2 . TYR F 1 330 ? 27.066  107.461 29.636  1.00 30.30  ? 330 TYR F CE2 1 
ATOM   20358 C CZ  . TYR F 1 330 ? 27.908  106.366 29.678  1.00 29.33  ? 330 TYR F CZ  1 
ATOM   20359 O OH  . TYR F 1 330 ? 29.097  106.405 30.314  1.00 29.10  ? 330 TYR F OH  1 
ATOM   20360 N N   . VAL F 1 331 ? 22.235  107.689 29.337  1.00 28.38  ? 331 VAL F N   1 
ATOM   20361 C CA  . VAL F 1 331 ? 21.950  108.664 30.381  1.00 30.20  ? 331 VAL F CA  1 
ATOM   20362 C C   . VAL F 1 331 ? 21.006  108.077 31.437  1.00 31.92  ? 331 VAL F C   1 
ATOM   20363 O O   . VAL F 1 331 ? 21.179  108.293 32.632  1.00 36.65  ? 331 VAL F O   1 
ATOM   20364 C CB  . VAL F 1 331 ? 21.348  109.933 29.745  1.00 29.36  ? 331 VAL F CB  1 
ATOM   20365 C CG1 . VAL F 1 331 ? 20.826  110.898 30.805  1.00 27.30  ? 331 VAL F CG1 1 
ATOM   20366 C CG2 . VAL F 1 331 ? 22.298  110.638 28.767  1.00 26.44  ? 331 VAL F CG2 1 
ATOM   20367 N N   . ALA F 1 332 ? 19.982  107.349 30.988  1.00 36.51  ? 332 ALA F N   1 
ATOM   20368 C CA  . ALA F 1 332 ? 19.043  106.690 31.882  1.00 35.36  ? 332 ALA F CA  1 
ATOM   20369 C C   . ALA F 1 332 ? 19.778  105.694 32.783  1.00 37.10  ? 332 ALA F C   1 
ATOM   20370 O O   . ALA F 1 332 ? 19.454  105.538 33.957  1.00 41.20  ? 332 ALA F O   1 
ATOM   20371 C CB  . ALA F 1 332 ? 17.952  106.010 31.079  1.00 33.48  ? 332 ALA F CB  1 
ATOM   20372 N N   . GLN F 1 333 ? 20.759  104.985 32.235  1.00 34.80  ? 333 GLN F N   1 
ATOM   20373 C CA  . GLN F 1 333 ? 21.373  103.922 33.004  1.00 33.00  ? 333 GLN F CA  1 
ATOM   20374 C C   . GLN F 1 333 ? 22.338  104.541 33.984  1.00 33.05  ? 333 GLN F C   1 
ATOM   20375 O O   . GLN F 1 333 ? 22.559  103.972 35.044  1.00 35.18  ? 333 GLN F O   1 
ATOM   20376 C CB  . GLN F 1 333 ? 22.085  102.901 32.125  1.00 30.89  ? 333 GLN F CB  1 
ATOM   20377 C CG  . GLN F 1 333 ? 21.116  101.926 31.483  1.00 28.51  ? 333 GLN F CG  1 
ATOM   20378 C CD  . GLN F 1 333 ? 21.774  101.137 30.392  1.00 30.86  ? 333 GLN F CD  1 
ATOM   20379 O OE1 . GLN F 1 333 ? 22.218  101.693 29.389  1.00 41.30  ? 333 GLN F OE1 1 
ATOM   20380 N NE2 . GLN F 1 333 ? 21.869  99.837  30.584  1.00 31.64  ? 333 GLN F NE2 1 
ATOM   20381 N N   . ARG F 1 334 ? 22.924  105.677 33.590  1.00 37.82  ? 334 ARG F N   1 
ATOM   20382 C CA  . ARG F 1 334 ? 23.833  106.408 34.459  1.00 40.19  ? 334 ARG F CA  1 
ATOM   20383 C C   . ARG F 1 334 ? 23.036  106.872 35.677  1.00 38.98  ? 334 ARG F C   1 
ATOM   20384 O O   . ARG F 1 334 ? 23.447  106.659 36.813  1.00 37.09  ? 334 ARG F O   1 
ATOM   20385 C CB  . ARG F 1 334 ? 24.473  107.570 33.692  1.00 43.04  ? 334 ARG F CB  1 
ATOM   20386 C CG  . ARG F 1 334 ? 25.405  108.428 34.534  1.00 43.81  ? 334 ARG F CG  1 
ATOM   20387 C CD  . ARG F 1 334 ? 26.046  109.560 33.754  1.00 42.51  ? 334 ARG F CD  1 
ATOM   20388 N NE  . ARG F 1 334 ? 26.976  110.310 34.603  1.00 47.11  ? 334 ARG F NE  1 
ATOM   20389 C CZ  . ARG F 1 334 ? 28.110  109.815 35.119  1.00 53.47  ? 334 ARG F CZ  1 
ATOM   20390 N NH1 . ARG F 1 334 ? 28.478  108.547 34.942  1.00 56.98  ? 334 ARG F NH1 1 
ATOM   20391 N NH2 . ARG F 1 334 ? 28.887  110.613 35.821  1.00 56.30  ? 334 ARG F NH2 1 
ATOM   20392 N N   . ASP F 1 335 ? 21.855  107.432 35.406  1.00 41.25  ? 335 ASP F N   1 
ATOM   20393 C CA  . ASP F 1 335 ? 20.943  107.872 36.442  1.00 42.17  ? 335 ASP F CA  1 
ATOM   20394 C C   . ASP F 1 335 ? 20.715  106.740 37.442  1.00 40.55  ? 335 ASP F C   1 
ATOM   20395 O O   . ASP F 1 335 ? 20.859  106.953 38.651  1.00 41.27  ? 335 ASP F O   1 
ATOM   20396 C CB  . ASP F 1 335 ? 19.656  108.442 35.871  1.00 46.16  ? 335 ASP F CB  1 
ATOM   20397 C CG  . ASP F 1 335 ? 18.696  108.903 36.960  1.00 53.12  ? 335 ASP F CG  1 
ATOM   20398 O OD1 . ASP F 1 335 ? 19.092  109.765 37.761  1.00 62.41  ? 335 ASP F OD1 1 
ATOM   20399 O OD2 . ASP F 1 335 ? 17.590  108.352 37.053  1.00 58.29  ? 335 ASP F OD2 1 
ATOM   20400 N N   . PHE F 1 336 ? 20.409  105.541 36.927  1.00 34.67  ? 336 PHE F N   1 
ATOM   20401 C CA  . PHE F 1 336 ? 20.169  104.381 37.765  1.00 33.43  ? 336 PHE F CA  1 
ATOM   20402 C C   . PHE F 1 336 ? 21.407  104.092 38.627  1.00 36.19  ? 336 PHE F C   1 
ATOM   20403 O O   . PHE F 1 336 ? 21.278  103.806 39.817  1.00 32.71  ? 336 PHE F O   1 
ATOM   20404 C CB  . PHE F 1 336 ? 19.744  103.181 36.908  1.00 30.94  ? 336 PHE F CB  1 
ATOM   20405 C CG  . PHE F 1 336 ? 19.384  101.949 37.731  1.00 29.90  ? 336 PHE F CG  1 
ATOM   20406 C CD1 . PHE F 1 336 ? 20.374  101.095 38.221  1.00 32.73  ? 336 PHE F CD1 1 
ATOM   20407 C CD2 . PHE F 1 336 ? 18.064  101.636 38.014  1.00 28.84  ? 336 PHE F CD2 1 
ATOM   20408 C CE1 . PHE F 1 336 ? 20.058  99.973  38.984  1.00 29.64  ? 336 PHE F CE1 1 
ATOM   20409 C CE2 . PHE F 1 336 ? 17.751  100.507 38.767  1.00 31.58  ? 336 PHE F CE2 1 
ATOM   20410 C CZ  . PHE F 1 336 ? 18.746  99.689  39.259  1.00 30.00  ? 336 PHE F CZ  1 
ATOM   20411 N N   . ALA F 1 337 ? 22.618  104.166 38.044  1.00 39.38  ? 337 ALA F N   1 
ATOM   20412 C CA  . ALA F 1 337 ? 23.845  103.884 38.792  1.00 36.86  ? 337 ALA F CA  1 
ATOM   20413 C C   . ALA F 1 337 ? 24.078  104.933 39.884  1.00 38.22  ? 337 ALA F C   1 
ATOM   20414 O O   . ALA F 1 337 ? 24.339  104.579 41.029  1.00 35.43  ? 337 ALA F O   1 
ATOM   20415 C CB  . ALA F 1 337 ? 25.040  103.787 37.874  1.00 34.28  ? 337 ALA F CB  1 
ATOM   20416 N N   . LEU F 1 338 ? 23.951  106.220 39.538  1.00 40.60  ? 338 LEU F N   1 
ATOM   20417 C CA  . LEU F 1 338 ? 24.166  107.287 40.508  1.00 44.56  ? 338 LEU F CA  1 
ATOM   20418 C C   . LEU F 1 338 ? 23.269  107.098 41.731  1.00 46.91  ? 338 LEU F C   1 
ATOM   20419 O O   . LEU F 1 338 ? 23.699  107.399 42.838  1.00 46.33  ? 338 LEU F O   1 
ATOM   20420 C CB  . LEU F 1 338 ? 23.942  108.666 39.891  1.00 41.38  ? 338 LEU F CB  1 
ATOM   20421 C CG  . LEU F 1 338 ? 24.994  109.113 38.871  1.00 46.06  ? 338 LEU F CG  1 
ATOM   20422 C CD1 . LEU F 1 338 ? 24.666  110.472 38.246  1.00 43.04  ? 338 LEU F CD1 1 
ATOM   20423 C CD2 . LEU F 1 338 ? 26.382  109.120 39.511  1.00 47.71  ? 338 LEU F CD2 1 
ATOM   20424 N N   . LYS F 1 339 ? 22.042  106.606 41.516  1.00 45.56  ? 339 LYS F N   1 
ATOM   20425 C CA  . LYS F 1 339 ? 21.049  106.473 42.571  1.00 49.28  ? 339 LYS F CA  1 
ATOM   20426 C C   . LYS F 1 339 ? 21.331  105.230 43.423  1.00 46.71  ? 339 LYS F C   1 
ATOM   20427 O O   . LYS F 1 339 ? 21.216  105.291 44.648  1.00 42.52  ? 339 LYS F O   1 
ATOM   20428 C CB  . LYS F 1 339 ? 19.684  106.500 41.875  1.00 54.75  ? 339 LYS F CB  1 
ATOM   20429 C CG  . LYS F 1 339 ? 18.452  106.619 42.759  1.00 76.09  ? 339 LYS F CG  1 
ATOM   20430 C CD  . LYS F 1 339 ? 17.152  106.528 41.957  1.00 84.07  ? 339 LYS F CD  1 
ATOM   20431 C CE  . LYS F 1 339 ? 15.889  106.387 42.770  1.00 77.47  ? 339 LYS F CE  1 
ATOM   20432 N NZ  . LYS F 1 339 ? 14.720  106.366 41.880  1.00 66.79  ? 339 LYS F NZ  1 
ATOM   20433 N N   . HIS F 1 340 ? 21.770  104.131 42.779  1.00 44.96  ? 340 HIS F N   1 
ATOM   20434 C CA  . HIS F 1 340 ? 21.750  102.801 43.382  1.00 44.20  ? 340 HIS F CA  1 
ATOM   20435 C C   . HIS F 1 340 ? 23.147  102.243 43.696  1.00 43.60  ? 340 HIS F C   1 
ATOM   20436 O O   . HIS F 1 340 ? 23.273  101.430 44.611  1.00 39.07  ? 340 HIS F O   1 
ATOM   20437 C CB  . HIS F 1 340 ? 20.976  101.805 42.502  1.00 45.17  ? 340 HIS F CB  1 
ATOM   20438 C CG  . HIS F 1 340 ? 19.511  102.084 42.346  1.00 44.65  ? 340 HIS F CG  1 
ATOM   20439 N ND1 . HIS F 1 340 ? 18.609  101.946 43.378  1.00 52.90  ? 340 HIS F ND1 1 
ATOM   20440 C CD2 . HIS F 1 340 ? 18.791  102.500 41.307  1.00 46.57  ? 340 HIS F CD2 1 
ATOM   20441 C CE1 . HIS F 1 340 ? 17.394  102.271 42.961  1.00 49.11  ? 340 HIS F CE1 1 
ATOM   20442 N NE2 . HIS F 1 340 ? 17.477  102.611 41.706  1.00 46.67  ? 340 HIS F NE2 1 
ATOM   20443 N N   . LEU F 1 341 ? 24.193  102.648 42.954  1.00 41.51  ? 341 LEU F N   1 
ATOM   20444 C CA  . LEU F 1 341 ? 25.518  102.048 43.108  1.00 44.63  ? 341 LEU F CA  1 
ATOM   20445 C C   . LEU F 1 341 ? 26.610  103.069 42.786  1.00 44.01  ? 341 LEU F C   1 
ATOM   20446 O O   . LEU F 1 341 ? 27.513  102.797 41.995  1.00 44.75  ? 341 LEU F O   1 
ATOM   20447 C CB  . LEU F 1 341 ? 25.682  100.798 42.238  1.00 47.59  ? 341 LEU F CB  1 
ATOM   20448 C CG  . LEU F 1 341 ? 25.332  100.941 40.744  1.00 48.09  ? 341 LEU F CG  1 
ATOM   20449 C CD1 . LEU F 1 341 ? 26.407  100.390 39.820  1.00 49.14  ? 341 LEU F CD1 1 
ATOM   20450 C CD2 . LEU F 1 341 ? 24.017  100.245 40.404  1.00 49.40  ? 341 LEU F CD2 1 
ATOM   20451 N N   . PRO F 1 342 ? 26.589  104.268 43.412  1.00 42.76  ? 342 PRO F N   1 
ATOM   20452 C CA  . PRO F 1 342 ? 27.479  105.356 42.998  1.00 40.48  ? 342 PRO F CA  1 
ATOM   20453 C C   . PRO F 1 342 ? 28.966  105.140 43.267  1.00 40.84  ? 342 PRO F C   1 
ATOM   20454 O O   . PRO F 1 342 ? 29.783  105.855 42.688  1.00 51.46  ? 342 PRO F O   1 
ATOM   20455 C CB  . PRO F 1 342 ? 26.921  106.556 43.786  1.00 41.97  ? 342 PRO F CB  1 
ATOM   20456 C CG  . PRO F 1 342 ? 26.326  105.943 45.043  1.00 40.74  ? 342 PRO F CG  1 
ATOM   20457 C CD  . PRO F 1 342 ? 25.727  104.628 44.553  1.00 41.47  ? 342 PRO F CD  1 
ATOM   20458 N N   . ASP F 1 343 ? 29.293  104.131 44.093  1.00 41.60  ? 343 ASP F N   1 
ATOM   20459 C CA  . ASP F 1 343 ? 30.638  103.889 44.598  1.00 41.04  ? 343 ASP F CA  1 
ATOM   20460 C C   . ASP F 1 343 ? 31.241  102.627 43.984  1.00 43.72  ? 343 ASP F C   1 
ATOM   20461 O O   . ASP F 1 343 ? 32.342  102.238 44.357  1.00 36.40  ? 343 ASP F O   1 
ATOM   20462 C CB  . ASP F 1 343 ? 30.642  103.728 46.114  1.00 40.13  ? 343 ASP F CB  1 
ATOM   20463 C CG  . ASP F 1 343 ? 30.127  104.928 46.906  1.00 47.71  ? 343 ASP F CG  1 
ATOM   20464 O OD1 . ASP F 1 343 ? 30.329  106.087 46.439  1.00 44.21  ? 343 ASP F OD1 1 
ATOM   20465 O OD2 . ASP F 1 343 ? 29.562  104.702 48.006  1.00 47.95  ? 343 ASP F OD2 1 
ATOM   20466 N N   . ASP F 1 344 ? 30.528  101.972 43.049  1.00 48.94  ? 344 ASP F N   1 
ATOM   20467 C CA  . ASP F 1 344 ? 31.020  100.736 42.442  1.00 45.26  ? 344 ASP F CA  1 
ATOM   20468 C C   . ASP F 1 344 ? 32.314  101.002 41.661  1.00 44.56  ? 344 ASP F C   1 
ATOM   20469 O O   . ASP F 1 344 ? 32.462  102.049 41.046  1.00 44.79  ? 344 ASP F O   1 
ATOM   20470 C CB  . ASP F 1 344 ? 29.936  100.114 41.591  1.00 40.50  ? 344 ASP F CB  1 
ATOM   20471 C CG  . ASP F 1 344 ? 30.230  98.708  41.111  1.00 40.79  ? 344 ASP F CG  1 
ATOM   20472 O OD1 . ASP F 1 344 ? 30.927  98.557  40.098  1.00 55.54  ? 344 ASP F OD1 1 
ATOM   20473 O OD2 . ASP F 1 344 ? 29.746  97.778  41.745  1.00 35.82  ? 344 ASP F OD2 1 
ATOM   20474 N N   . GLU F 1 345 ? 33.279  100.075 41.712  1.00 44.80  ? 345 GLU F N   1 
ATOM   20475 C CA  . GLU F 1 345 ? 34.548  100.256 41.017  1.00 46.73  ? 345 GLU F CA  1 
ATOM   20476 C C   . GLU F 1 345 ? 34.367  100.361 39.496  1.00 45.20  ? 345 GLU F C   1 
ATOM   20477 O O   . GLU F 1 345 ? 34.863  101.299 38.870  1.00 35.74  ? 345 GLU F O   1 
ATOM   20478 C CB  . GLU F 1 345 ? 35.464  99.058  41.230  1.00 53.01  ? 345 GLU F CB  1 
ATOM   20479 C CG  . GLU F 1 345 ? 36.485  99.241  42.343  1.00 61.90  ? 345 GLU F CG  1 
ATOM   20480 C CD  . GLU F 1 345 ? 37.759  98.481  42.024  1.00 60.15  ? 345 GLU F CD  1 
ATOM   20481 O OE1 . GLU F 1 345 ? 38.808  99.116  42.210  1.00 61.29  ? 345 GLU F OE1 1 
ATOM   20482 O OE2 . GLU F 1 345 ? 37.711  97.315  41.557  1.00 53.30  ? 345 GLU F OE2 1 
ATOM   20483 N N   . LEU F 1 346 ? 33.689  99.351  38.915  1.00 43.51  ? 346 LEU F N   1 
ATOM   20484 C CA  . LEU F 1 346 ? 33.466  99.273  37.479  1.00 41.70  ? 346 LEU F CA  1 
ATOM   20485 C C   . LEU F 1 346 ? 32.730  100.534 37.016  1.00 39.30  ? 346 LEU F C   1 
ATOM   20486 O O   . LEU F 1 346 ? 33.049  101.088 35.960  1.00 35.77  ? 346 LEU F O   1 
ATOM   20487 C CB  . LEU F 1 346 ? 32.718  97.994  37.091  1.00 39.33  ? 346 LEU F CB  1 
ATOM   20488 C CG  . LEU F 1 346 ? 33.459  96.662  37.258  1.00 43.09  ? 346 LEU F CG  1 
ATOM   20489 C CD1 . LEU F 1 346 ? 32.822  95.618  36.343  1.00 45.13  ? 346 LEU F CD1 1 
ATOM   20490 C CD2 . LEU F 1 346 ? 34.983  96.679  37.027  1.00 44.34  ? 346 LEU F CD2 1 
ATOM   20491 N N   . PHE F 1 347 ? 31.761  100.996 37.819  1.00 37.58  ? 347 PHE F N   1 
ATOM   20492 C CA  . PHE F 1 347 ? 30.977  102.160 37.452  1.00 37.45  ? 347 PHE F CA  1 
ATOM   20493 C C   . PHE F 1 347 ? 31.908  103.367 37.343  1.00 44.49  ? 347 PHE F C   1 
ATOM   20494 O O   . PHE F 1 347 ? 31.767  104.188 36.427  1.00 47.12  ? 347 PHE F O   1 
ATOM   20495 C CB  . PHE F 1 347 ? 29.823  102.367 38.430  1.00 33.99  ? 347 PHE F CB  1 
ATOM   20496 C CG  . PHE F 1 347 ? 29.122  103.687 38.180  1.00 35.09  ? 347 PHE F CG  1 
ATOM   20497 C CD1 . PHE F 1 347 ? 28.675  104.023 36.914  1.00 31.42  ? 347 PHE F CD1 1 
ATOM   20498 C CD2 . PHE F 1 347 ? 28.969  104.618 39.204  1.00 40.64  ? 347 PHE F CD2 1 
ATOM   20499 C CE1 . PHE F 1 347 ? 28.072  105.244 36.683  1.00 35.15  ? 347 PHE F CE1 1 
ATOM   20500 C CE2 . PHE F 1 347 ? 28.354  105.841 38.974  1.00 39.52  ? 347 PHE F CE2 1 
ATOM   20501 C CZ  . PHE F 1 347 ? 27.905  106.150 37.709  1.00 41.21  ? 347 PHE F CZ  1 
ATOM   20502 N N   . LYS F 1 348 ? 32.902  103.436 38.242  1.00 45.74  ? 348 LYS F N   1 
ATOM   20503 C CA  . LYS F 1 348 ? 33.911  104.485 38.179  1.00 49.56  ? 348 LYS F CA  1 
ATOM   20504 C C   . LYS F 1 348 ? 34.669  104.443 36.846  1.00 42.38  ? 348 LYS F C   1 
ATOM   20505 O O   . LYS F 1 348 ? 34.918  105.481 36.245  1.00 39.34  ? 348 LYS F O   1 
ATOM   20506 C CB  . LYS F 1 348 ? 34.890  104.435 39.358  1.00 53.59  ? 348 LYS F CB  1 
ATOM   20507 C CG  . LYS F 1 348 ? 34.457  105.271 40.547  1.00 64.19  ? 348 LYS F CG  1 
ATOM   20508 C CD  . LYS F 1 348 ? 35.283  105.011 41.807  1.00 79.58  ? 348 LYS F CD  1 
ATOM   20509 C CE  . LYS F 1 348 ? 34.621  105.486 43.072  1.00 81.72  ? 348 LYS F CE  1 
ATOM   20510 N NZ  . LYS F 1 348 ? 34.403  106.933 43.048  1.00 82.47  ? 348 LYS F NZ  1 
ATOM   20511 N N   . ILE F 1 349 ? 35.020  103.246 36.378  1.00 35.74  ? 349 ILE F N   1 
ATOM   20512 C CA  . ILE F 1 349 ? 35.707  103.099 35.106  1.00 37.90  ? 349 ILE F CA  1 
ATOM   20513 C C   . ILE F 1 349 ? 34.821  103.527 33.940  1.00 35.44  ? 349 ILE F C   1 
ATOM   20514 O O   . ILE F 1 349 ? 35.323  104.089 32.976  1.00 32.05  ? 349 ILE F O   1 
ATOM   20515 C CB  . ILE F 1 349 ? 36.185  101.661 34.908  1.00 39.96  ? 349 ILE F CB  1 
ATOM   20516 C CG1 . ILE F 1 349 ? 37.253  101.328 35.959  1.00 44.57  ? 349 ILE F CG1 1 
ATOM   20517 C CG2 . ILE F 1 349 ? 36.681  101.490 33.471  1.00 39.95  ? 349 ILE F CG2 1 
ATOM   20518 C CD1 . ILE F 1 349 ? 37.711  99.880  35.988  1.00 48.57  ? 349 ILE F CD1 1 
ATOM   20519 N N   . VAL F 1 350 ? 33.523  103.208 34.017  1.00 37.83  ? 350 VAL F N   1 
ATOM   20520 C CA  . VAL F 1 350 ? 32.557  103.619 33.011  1.00 35.48  ? 350 VAL F CA  1 
ATOM   20521 C C   . VAL F 1 350 ? 32.433  105.145 33.018  1.00 36.84  ? 350 VAL F C   1 
ATOM   20522 O O   . VAL F 1 350 ? 32.345  105.767 31.959  1.00 39.86  ? 350 VAL F O   1 
ATOM   20523 C CB  . VAL F 1 350 ? 31.197  102.931 33.261  1.00 35.45  ? 350 VAL F CB  1 
ATOM   20524 C CG1 . VAL F 1 350 ? 30.074  103.544 32.432  1.00 34.43  ? 350 VAL F CG1 1 
ATOM   20525 C CG2 . VAL F 1 350 ? 31.254  101.420 33.057  1.00 35.36  ? 350 VAL F CG2 1 
ATOM   20526 N N   . SER F 1 351 ? 32.382  105.749 34.211  1.00 37.39  ? 351 SER F N   1 
ATOM   20527 C CA  . SER F 1 351 ? 32.282  107.197 34.295  1.00 40.42  ? 351 SER F CA  1 
ATOM   20528 C C   . SER F 1 351 ? 33.527  107.825 33.682  1.00 35.72  ? 351 SER F C   1 
ATOM   20529 O O   . SER F 1 351 ? 33.430  108.826 32.992  1.00 32.62  ? 351 SER F O   1 
ATOM   20530 C CB  . SER F 1 351 ? 32.096  107.684 35.718  1.00 44.38  ? 351 SER F CB  1 
ATOM   20531 O OG  . SER F 1 351 ? 30.855  107.259 36.261  1.00 52.15  ? 351 SER F OG  1 
ATOM   20532 N N   . LEU F 1 352 ? 34.693  107.236 33.967  1.00 34.80  ? 352 LEU F N   1 
ATOM   20533 C CA  . LEU F 1 352 ? 35.962  107.735 33.452  1.00 37.84  ? 352 LEU F CA  1 
ATOM   20534 C C   . LEU F 1 352 ? 35.933  107.638 31.919  1.00 36.61  ? 352 LEU F C   1 
ATOM   20535 O O   . LEU F 1 352 ? 36.270  108.584 31.199  1.00 35.07  ? 352 LEU F O   1 
ATOM   20536 C CB  . LEU F 1 352 ? 37.106  106.903 34.049  1.00 36.63  ? 352 LEU F CB  1 
ATOM   20537 C CG  . LEU F 1 352 ? 38.446  107.585 34.371  1.00 40.10  ? 352 LEU F CG  1 
ATOM   20538 C CD1 . LEU F 1 352 ? 39.576  106.664 33.904  1.00 39.99  ? 352 LEU F CD1 1 
ATOM   20539 C CD2 . LEU F 1 352 ? 38.676  109.025 33.881  1.00 38.47  ? 352 LEU F CD2 1 
ATOM   20540 N N   . CYS F 1 353 ? 35.527  106.463 31.426  1.00 33.20  ? 353 CYS F N   1 
ATOM   20541 C CA  . CYS F 1 353 ? 35.424  106.225 30.000  1.00 33.76  ? 353 CYS F CA  1 
ATOM   20542 C C   . CYS F 1 353 ? 34.568  107.316 29.345  1.00 34.53  ? 353 CYS F C   1 
ATOM   20543 O O   . CYS F 1 353 ? 34.829  107.682 28.205  1.00 36.14  ? 353 CYS F O   1 
ATOM   20544 C CB  . CYS F 1 353 ? 34.949  104.796 29.739  1.00 31.46  ? 353 CYS F CB  1 
ATOM   20545 S SG  . CYS F 1 353 ? 36.258  103.545 29.869  1.00 32.33  ? 353 CYS F SG  1 
ATOM   20546 N N   . TYR F 1 354 ? 33.559  107.853 30.050  1.00 35.37  ? 354 TYR F N   1 
ATOM   20547 C CA  . TYR F 1 354 ? 32.641  108.829 29.461  1.00 36.79  ? 354 TYR F CA  1 
ATOM   20548 C C   . TYR F 1 354 ? 33.340  110.166 29.190  1.00 36.98  ? 354 TYR F C   1 
ATOM   20549 O O   . TYR F 1 354 ? 32.977  110.868 28.251  1.00 35.00  ? 354 TYR F O   1 
ATOM   20550 C CB  . TYR F 1 354 ? 31.419  108.898 30.388  1.00 38.39  ? 354 TYR F CB  1 
ATOM   20551 C CG  . TYR F 1 354 ? 30.214  109.765 30.021  1.00 43.68  ? 354 TYR F CG  1 
ATOM   20552 C CD1 . TYR F 1 354 ? 29.935  110.187 28.725  1.00 43.44  ? 354 TYR F CD1 1 
ATOM   20553 C CD2 . TYR F 1 354 ? 29.296  110.113 31.008  1.00 53.74  ? 354 TYR F CD2 1 
ATOM   20554 C CE1 . TYR F 1 354 ? 28.817  110.954 28.436  1.00 46.90  ? 354 TYR F CE1 1 
ATOM   20555 C CE2 . TYR F 1 354 ? 28.172  110.879 30.734  1.00 54.60  ? 354 TYR F CE2 1 
ATOM   20556 C CZ  . TYR F 1 354 ? 27.928  111.303 29.442  1.00 52.62  ? 354 TYR F CZ  1 
ATOM   20557 O OH  . TYR F 1 354 ? 26.803  112.063 29.241  1.00 55.71  ? 354 TYR F OH  1 
ATOM   20558 N N   . GLU F 1 355 ? 34.350  110.513 30.002  1.00 44.99  ? 355 GLU F N   1 
ATOM   20559 C CA  . GLU F 1 355 ? 35.187  111.690 29.780  1.00 53.75  ? 355 GLU F CA  1 
ATOM   20560 C C   . GLU F 1 355 ? 36.232  111.435 28.689  1.00 49.14  ? 355 GLU F C   1 
ATOM   20561 O O   . GLU F 1 355 ? 36.377  112.234 27.761  1.00 41.88  ? 355 GLU F O   1 
ATOM   20562 C CB  . GLU F 1 355 ? 35.905  112.124 31.064  1.00 65.12  ? 355 GLU F CB  1 
ATOM   20563 C CG  . GLU F 1 355 ? 35.205  113.242 31.835  1.00 86.02  ? 355 GLU F CG  1 
ATOM   20564 C CD  . GLU F 1 355 ? 33.697  113.414 31.623  1.00 112.31 ? 355 GLU F CD  1 
ATOM   20565 O OE1 . GLU F 1 355 ? 33.286  114.584 31.447  1.00 122.25 ? 355 GLU F OE1 1 
ATOM   20566 O OE2 . GLU F 1 355 ? 32.921  112.426 31.610  1.00 127.78 ? 355 GLU F OE2 1 
ATOM   20567 N N   . VAL F 1 356 ? 36.939  110.304 28.801  1.00 43.84  ? 356 VAL F N   1 
ATOM   20568 C CA  . VAL F 1 356 ? 38.148  110.063 28.032  1.00 46.56  ? 356 VAL F CA  1 
ATOM   20569 C C   . VAL F 1 356 ? 37.838  109.546 26.623  1.00 45.71  ? 356 VAL F C   1 
ATOM   20570 O O   . VAL F 1 356 ? 38.382  110.105 25.665  1.00 49.50  ? 356 VAL F O   1 
ATOM   20571 C CB  . VAL F 1 356 ? 39.072  109.105 28.803  1.00 45.88  ? 356 VAL F CB  1 
ATOM   20572 C CG1 . VAL F 1 356 ? 40.256  108.650 27.977  1.00 46.99  ? 356 VAL F CG1 1 
ATOM   20573 C CG2 . VAL F 1 356 ? 39.570  109.739 30.088  1.00 46.51  ? 356 VAL F CG2 1 
ATOM   20574 N N   . ILE F 1 357 ? 36.999  108.496 26.484  1.00 41.90  ? 357 ILE F N   1 
ATOM   20575 C CA  . ILE F 1 357 ? 36.859  107.781 25.211  1.00 41.74  ? 357 ILE F CA  1 
ATOM   20576 C C   . ILE F 1 357 ? 36.349  108.706 24.104  1.00 38.09  ? 357 ILE F C   1 
ATOM   20577 O O   . ILE F 1 357 ? 36.889  108.670 23.006  1.00 35.90  ? 357 ILE F O   1 
ATOM   20578 C CB  . ILE F 1 357 ? 35.995  106.507 25.308  1.00 38.99  ? 357 ILE F CB  1 
ATOM   20579 C CG1 . ILE F 1 357 ? 36.611  105.480 26.254  1.00 39.55  ? 357 ILE F CG1 1 
ATOM   20580 C CG2 . ILE F 1 357 ? 35.758  105.890 23.926  1.00 36.74  ? 357 ILE F CG2 1 
ATOM   20581 C CD1 . ILE F 1 357 ? 37.976  104.978 25.837  1.00 40.71  ? 357 ILE F CD1 1 
ATOM   20582 N N   . PRO F 1 358 ? 35.326  109.559 24.336  1.00 33.11  ? 358 PRO F N   1 
ATOM   20583 C CA  . PRO F 1 358 ? 34.914  110.529 23.328  1.00 35.99  ? 358 PRO F CA  1 
ATOM   20584 C C   . PRO F 1 358 ? 36.085  111.391 22.867  1.00 40.71  ? 358 PRO F C   1 
ATOM   20585 O O   . PRO F 1 358 ? 36.179  111.733 21.677  1.00 34.26  ? 358 PRO F O   1 
ATOM   20586 C CB  . PRO F 1 358 ? 33.809  111.333 24.026  1.00 32.93  ? 358 PRO F CB  1 
ATOM   20587 C CG  . PRO F 1 358 ? 33.269  110.345 25.021  1.00 33.84  ? 358 PRO F CG  1 
ATOM   20588 C CD  . PRO F 1 358 ? 34.495  109.622 25.543  1.00 31.73  ? 358 PRO F CD  1 
ATOM   20589 N N   . GLU F 1 359 ? 36.966  111.728 23.822  1.00 44.36  ? 359 GLU F N   1 
ATOM   20590 C CA  . GLU F 1 359 ? 38.082  112.606 23.532  1.00 47.20  ? 359 GLU F CA  1 
ATOM   20591 C C   . GLU F 1 359 ? 38.977  111.871 22.551  1.00 43.30  ? 359 GLU F C   1 
ATOM   20592 O O   . GLU F 1 359 ? 39.295  112.435 21.508  1.00 43.47  ? 359 GLU F O   1 
ATOM   20593 C CB  . GLU F 1 359 ? 38.825  113.138 24.758  1.00 54.31  ? 359 GLU F CB  1 
ATOM   20594 C CG  . GLU F 1 359 ? 38.249  114.466 25.253  1.00 71.71  ? 359 GLU F CG  1 
ATOM   20595 C CD  . GLU F 1 359 ? 38.044  115.564 24.194  1.00 86.57  ? 359 GLU F CD  1 
ATOM   20596 O OE1 . GLU F 1 359 ? 36.874  116.000 23.979  1.00 84.33  ? 359 GLU F OE1 1 
ATOM   20597 O OE2 . GLU F 1 359 ? 39.053  115.995 23.570  1.00 83.43  ? 359 GLU F OE2 1 
ATOM   20598 N N   . VAL F 1 360 ? 39.311  110.616 22.878  1.00 35.90  ? 360 VAL F N   1 
ATOM   20599 C CA  . VAL F 1 360 ? 40.125  109.778 22.018  1.00 35.64  ? 360 VAL F CA  1 
ATOM   20600 C C   . VAL F 1 360 ? 39.498  109.652 20.625  1.00 38.92  ? 360 VAL F C   1 
ATOM   20601 O O   . VAL F 1 360 ? 40.208  109.776 19.625  1.00 36.38  ? 360 VAL F O   1 
ATOM   20602 C CB  . VAL F 1 360 ? 40.355  108.394 22.641  1.00 35.63  ? 360 VAL F CB  1 
ATOM   20603 C CG1 . VAL F 1 360 ? 40.938  107.406 21.640  1.00 35.05  ? 360 VAL F CG1 1 
ATOM   20604 C CG2 . VAL F 1 360 ? 41.231  108.488 23.890  1.00 36.91  ? 360 VAL F CG2 1 
ATOM   20605 N N   . LEU F 1 361 ? 38.175  109.433 20.553  1.00 36.78  ? 361 LEU F N   1 
ATOM   20606 C CA  . LEU F 1 361 ? 37.542  109.113 19.287  1.00 35.35  ? 361 LEU F CA  1 
ATOM   20607 C C   . LEU F 1 361 ? 37.457  110.358 18.407  1.00 36.22  ? 361 LEU F C   1 
ATOM   20608 O O   . LEU F 1 361 ? 37.447  110.243 17.182  1.00 40.85  ? 361 LEU F O   1 
ATOM   20609 C CB  . LEU F 1 361 ? 36.185  108.455 19.520  1.00 36.20  ? 361 LEU F CB  1 
ATOM   20610 C CG  . LEU F 1 361 ? 36.215  106.973 19.911  1.00 36.76  ? 361 LEU F CG  1 
ATOM   20611 C CD1 . LEU F 1 361 ? 34.798  106.436 20.043  1.00 38.16  ? 361 LEU F CD1 1 
ATOM   20612 C CD2 . LEU F 1 361 ? 36.994  106.143 18.905  1.00 38.81  ? 361 LEU F CD2 1 
ATOM   20613 N N   . LYS F 1 362 ? 37.431  111.545 19.022  1.00 37.42  ? 362 LYS F N   1 
ATOM   20614 C CA  . LYS F 1 362 ? 37.456  112.792 18.272  1.00 39.92  ? 362 LYS F CA  1 
ATOM   20615 C C   . LYS F 1 362 ? 38.816  112.941 17.586  1.00 41.51  ? 362 LYS F C   1 
ATOM   20616 O O   . LYS F 1 362 ? 38.890  113.315 16.412  1.00 39.92  ? 362 LYS F O   1 
ATOM   20617 C CB  . LYS F 1 362 ? 37.159  114.025 19.135  1.00 39.70  ? 362 LYS F CB  1 
ATOM   20618 C CG  . LYS F 1 362 ? 35.724  114.159 19.629  1.00 45.87  ? 362 LYS F CG  1 
ATOM   20619 C CD  . LYS F 1 362 ? 35.590  115.126 20.799  1.00 52.28  ? 362 LYS F CD  1 
ATOM   20620 C CE  . LYS F 1 362 ? 34.216  115.270 21.349  1.00 59.45  ? 362 LYS F CE  1 
ATOM   20621 N NZ  . LYS F 1 362 ? 33.381  116.051 20.433  1.00 70.89  ? 362 LYS F NZ  1 
ATOM   20622 N N   . LYS F 1 363 ? 39.881  112.636 18.333  1.00 39.69  ? 363 LYS F N   1 
ATOM   20623 C CA  . LYS F 1 363 ? 41.243  112.860 17.881  1.00 42.30  ? 363 LYS F CA  1 
ATOM   20624 C C   . LYS F 1 363 ? 41.624  111.834 16.817  1.00 41.57  ? 363 LYS F C   1 
ATOM   20625 O O   . LYS F 1 363 ? 42.364  112.140 15.883  1.00 42.32  ? 363 LYS F O   1 
ATOM   20626 C CB  . LYS F 1 363 ? 42.170  112.751 19.093  1.00 45.88  ? 363 LYS F CB  1 
ATOM   20627 C CG  . LYS F 1 363 ? 42.085  113.909 20.065  1.00 45.23  ? 363 LYS F CG  1 
ATOM   20628 C CD  . LYS F 1 363 ? 42.842  113.676 21.367  1.00 47.61  ? 363 LYS F CD  1 
ATOM   20629 C CE  . LYS F 1 363 ? 42.794  114.921 22.219  1.00 55.48  ? 363 LYS F CE  1 
ATOM   20630 N NZ  . LYS F 1 363 ? 43.212  114.671 23.597  1.00 56.71  ? 363 LYS F NZ  1 
ATOM   20631 N N   . HIS F 1 364 ? 41.101  110.618 16.988  1.00 40.05  ? 364 HIS F N   1 
ATOM   20632 C CA  . HIS F 1 364 ? 41.294  109.520 16.062  1.00 41.02  ? 364 HIS F CA  1 
ATOM   20633 C C   . HIS F 1 364 ? 40.605  109.829 14.740  1.00 39.96  ? 364 HIS F C   1 
ATOM   20634 O O   . HIS F 1 364 ? 41.049  109.355 13.713  1.00 43.08  ? 364 HIS F O   1 
ATOM   20635 C CB  . HIS F 1 364 ? 40.766  108.228 16.697  1.00 42.76  ? 364 HIS F CB  1 
ATOM   20636 C CG  . HIS F 1 364 ? 40.785  107.002 15.847  1.00 39.84  ? 364 HIS F CG  1 
ATOM   20637 N ND1 . HIS F 1 364 ? 39.625  106.410 15.389  1.00 34.09  ? 364 HIS F ND1 1 
ATOM   20638 C CD2 . HIS F 1 364 ? 41.802  106.224 15.443  1.00 38.70  ? 364 HIS F CD2 1 
ATOM   20639 C CE1 . HIS F 1 364 ? 39.953  105.300 14.737  1.00 38.65  ? 364 HIS F CE1 1 
ATOM   20640 N NE2 . HIS F 1 364 ? 41.267  105.173 14.742  1.00 36.64  ? 364 HIS F NE2 1 
ATOM   20641 N N   . GLY F 1 365 ? 39.476  110.538 14.780  1.00 42.57  ? 365 GLY F N   1 
ATOM   20642 C CA  . GLY F 1 365 ? 38.978  111.235 13.602  1.00 45.36  ? 365 GLY F CA  1 
ATOM   20643 C C   . GLY F 1 365 ? 38.030  110.432 12.704  1.00 47.16  ? 365 GLY F C   1 
ATOM   20644 O O   . GLY F 1 365 ? 37.530  111.027 11.752  1.00 46.68  ? 365 GLY F O   1 
ATOM   20645 N N   . LYS F 1 366 ? 37.756  109.144 13.011  1.00 41.74  ? 366 LYS F N   1 
ATOM   20646 C CA  . LYS F 1 366 ? 36.970  108.277 12.136  1.00 41.87  ? 366 LYS F CA  1 
ATOM   20647 C C   . LYS F 1 366 ? 35.497  108.179 12.553  1.00 41.30  ? 366 LYS F C   1 
ATOM   20648 O O   . LYS F 1 366 ? 34.629  108.123 11.683  1.00 36.15  ? 366 LYS F O   1 
ATOM   20649 C CB  . LYS F 1 366 ? 37.526  106.855 11.970  1.00 43.23  ? 366 LYS F CB  1 
ATOM   20650 C CG  . LYS F 1 366 ? 38.962  106.833 11.441  1.00 48.54  ? 366 LYS F CG  1 
ATOM   20651 C CD  . LYS F 1 366 ? 39.542  105.496 11.000  1.00 54.47  ? 366 LYS F CD  1 
ATOM   20652 C CE  . LYS F 1 366 ? 39.597  105.335 9.505   1.00 66.11  ? 366 LYS F CE  1 
ATOM   20653 N NZ  . LYS F 1 366 ? 40.289  104.105 9.107   1.00 66.23  ? 366 LYS F NZ  1 
ATOM   20654 N N   . ALA F 1 367 ? 35.192  108.112 13.855  1.00 36.70  ? 367 ALA F N   1 
ATOM   20655 C CA  . ALA F 1 367 ? 33.813  107.870 14.249  1.00 35.82  ? 367 ALA F CA  1 
ATOM   20656 C C   . ALA F 1 367 ? 32.948  109.113 14.020  1.00 38.09  ? 367 ALA F C   1 
ATOM   20657 O O   . ALA F 1 367 ? 33.310  110.217 14.408  1.00 34.43  ? 367 ALA F O   1 
ATOM   20658 C CB  . ALA F 1 367 ? 33.752  107.409 15.678  1.00 37.05  ? 367 ALA F CB  1 
ATOM   20659 N N   . LYS F 1 368 ? 31.794  108.928 13.369  1.00 39.04  ? 368 LYS F N   1 
ATOM   20660 C CA  . LYS F 1 368 ? 30.868  110.023 13.149  1.00 44.43  ? 368 LYS F CA  1 
ATOM   20661 C C   . LYS F 1 368 ? 30.204  110.394 14.466  1.00 40.17  ? 368 LYS F C   1 
ATOM   20662 O O   . LYS F 1 368 ? 29.772  111.528 14.627  1.00 36.84  ? 368 LYS F O   1 
ATOM   20663 C CB  . LYS F 1 368 ? 29.792  109.668 12.119  1.00 52.17  ? 368 LYS F CB  1 
ATOM   20664 C CG  . LYS F 1 368 ? 30.332  109.548 10.700  1.00 61.76  ? 368 LYS F CG  1 
ATOM   20665 C CD  . LYS F 1 368 ? 30.455  110.859 9.933   1.00 67.58  ? 368 LYS F CD  1 
ATOM   20666 C CE  . LYS F 1 368 ? 30.924  110.679 8.517   1.00 70.91  ? 368 LYS F CE  1 
ATOM   20667 N NZ  . LYS F 1 368 ? 30.685  111.896 7.737   1.00 74.68  ? 368 LYS F NZ  1 
ATOM   20668 N N   . ASN F 1 369 ? 30.107  109.417 15.378  1.00 38.21  ? 369 ASN F N   1 
ATOM   20669 C CA  . ASN F 1 369 ? 29.578  109.642 16.711  1.00 35.42  ? 369 ASN F CA  1 
ATOM   20670 C C   . ASN F 1 369 ? 30.589  109.150 17.745  1.00 34.29  ? 369 ASN F C   1 
ATOM   20671 O O   . ASN F 1 369 ? 30.735  107.947 17.921  1.00 31.60  ? 369 ASN F O   1 
ATOM   20672 C CB  . ASN F 1 369 ? 28.235  108.940 16.872  1.00 35.66  ? 369 ASN F CB  1 
ATOM   20673 C CG  . ASN F 1 369 ? 27.769  108.894 18.309  1.00 33.71  ? 369 ASN F CG  1 
ATOM   20674 O OD1 . ASN F 1 369 ? 28.141  109.761 19.107  1.00 35.33  ? 369 ASN F OD1 1 
ATOM   20675 N ND2 . ASN F 1 369 ? 26.946  107.914 18.651  1.00 29.88  ? 369 ASN F ND2 1 
ATOM   20676 N N   . PRO F 1 370 ? 31.263  110.054 18.502  1.00 34.35  ? 370 PRO F N   1 
ATOM   20677 C CA  . PRO F 1 370 ? 32.253  109.655 19.506  1.00 32.78  ? 370 PRO F CA  1 
ATOM   20678 C C   . PRO F 1 370 ? 31.674  109.281 20.872  1.00 32.02  ? 370 PRO F C   1 
ATOM   20679 O O   . PRO F 1 370 ? 32.392  108.820 21.758  1.00 28.31  ? 370 PRO F O   1 
ATOM   20680 C CB  . PRO F 1 370 ? 33.102  110.942 19.571  1.00 31.16  ? 370 PRO F CB  1 
ATOM   20681 C CG  . PRO F 1 370 ? 32.092  112.056 19.472  1.00 30.86  ? 370 PRO F CG  1 
ATOM   20682 C CD  . PRO F 1 370 ? 31.081  111.519 18.464  1.00 32.96  ? 370 PRO F CD  1 
ATOM   20683 N N   . TRP F 1 371 ? 30.352  109.421 21.015  1.00 33.41  ? 371 TRP F N   1 
ATOM   20684 C CA  . TRP F 1 371 ? 29.735  109.320 22.328  1.00 35.60  ? 371 TRP F CA  1 
ATOM   20685 C C   . TRP F 1 371 ? 29.296  107.889 22.620  1.00 33.91  ? 371 TRP F C   1 
ATOM   20686 O O   . TRP F 1 371 ? 29.285  107.032 21.730  1.00 32.27  ? 371 TRP F O   1 
ATOM   20687 C CB  . TRP F 1 371 ? 28.593  110.334 22.438  1.00 37.16  ? 371 TRP F CB  1 
ATOM   20688 C CG  . TRP F 1 371 ? 29.061  111.753 22.223  1.00 38.01  ? 371 TRP F CG  1 
ATOM   20689 C CD1 . TRP F 1 371 ? 28.911  112.511 21.103  1.00 37.48  ? 371 TRP F CD1 1 
ATOM   20690 C CD2 . TRP F 1 371 ? 29.796  112.570 23.156  1.00 40.70  ? 371 TRP F CD2 1 
ATOM   20691 N NE1 . TRP F 1 371 ? 29.480  113.741 21.268  1.00 37.66  ? 371 TRP F NE1 1 
ATOM   20692 C CE2 . TRP F 1 371 ? 30.029  113.812 22.516  1.00 39.38  ? 371 TRP F CE2 1 
ATOM   20693 C CE3 . TRP F 1 371 ? 30.273  112.368 24.460  1.00 39.76  ? 371 TRP F CE3 1 
ATOM   20694 C CZ2 . TRP F 1 371 ? 30.719  114.853 23.131  1.00 36.51  ? 371 TRP F CZ2 1 
ATOM   20695 C CZ3 . TRP F 1 371 ? 30.969  113.392 25.063  1.00 41.99  ? 371 TRP F CZ3 1 
ATOM   20696 C CH2 . TRP F 1 371 ? 31.179  114.616 24.408  1.00 40.34  ? 371 TRP F CH2 1 
ATOM   20697 N N   . PRO F 1 372 ? 29.038  107.568 23.906  1.00 31.92  ? 372 PRO F N   1 
ATOM   20698 C CA  . PRO F 1 372 ? 28.630  106.221 24.292  1.00 34.44  ? 372 PRO F CA  1 
ATOM   20699 C C   . PRO F 1 372 ? 27.193  105.913 23.889  1.00 34.14  ? 372 PRO F C   1 
ATOM   20700 O O   . PRO F 1 372 ? 26.365  106.813 23.780  1.00 32.04  ? 372 PRO F O   1 
ATOM   20701 C CB  . PRO F 1 372 ? 28.798  106.175 25.802  1.00 32.02  ? 372 PRO F CB  1 
ATOM   20702 C CG  . PRO F 1 372 ? 28.665  107.604 26.205  1.00 33.04  ? 372 PRO F CG  1 
ATOM   20703 C CD  . PRO F 1 372 ? 29.227  108.442 25.065  1.00 32.98  ? 372 PRO F CD  1 
ATOM   20704 N N   . ASN F 1 373 ? 26.964  104.614 23.678  1.00 31.34  ? 373 ASN F N   1 
ATOM   20705 C CA  . ASN F 1 373 ? 25.678  104.065 23.328  1.00 31.09  ? 373 ASN F CA  1 
ATOM   20706 C C   . ASN F 1 373 ? 25.247  103.198 24.499  1.00 33.53  ? 373 ASN F C   1 
ATOM   20707 O O   . ASN F 1 373 ? 26.023  103.015 25.440  1.00 30.82  ? 373 ASN F O   1 
ATOM   20708 C CB  . ASN F 1 373 ? 25.727  103.298 22.005  1.00 28.69  ? 373 ASN F CB  1 
ATOM   20709 C CG  . ASN F 1 373 ? 26.635  102.091 22.034  1.00 30.02  ? 373 ASN F CG  1 
ATOM   20710 O OD1 . ASN F 1 373 ? 26.444  101.174 22.846  1.00 33.98  ? 373 ASN F OD1 1 
ATOM   20711 N ND2 . ASN F 1 373 ? 27.610  102.046 21.135  1.00 29.20  ? 373 ASN F ND2 1 
ATOM   20712 N N   . VAL F 1 374 ? 24.029  102.644 24.372  1.00 33.42  ? 374 VAL F N   1 
ATOM   20713 C CA  . VAL F 1 374 ? 23.379  101.836 25.391  1.00 30.33  ? 374 VAL F CA  1 
ATOM   20714 C C   . VAL F 1 374 ? 24.299  100.743 25.946  1.00 28.51  ? 374 VAL F C   1 
ATOM   20715 O O   . VAL F 1 374 ? 24.135  100.411 27.119  1.00 29.72  ? 374 VAL F O   1 
ATOM   20716 C CB  . VAL F 1 374 ? 22.031  101.244 24.909  1.00 30.33  ? 374 VAL F CB  1 
ATOM   20717 C CG1 . VAL F 1 374 ? 22.154  100.356 23.668  1.00 27.71  ? 374 VAL F CG1 1 
ATOM   20718 C CG2 . VAL F 1 374 ? 21.339  100.477 26.034  1.00 31.44  ? 374 VAL F CG2 1 
ATOM   20719 N N   . ASP F 1 375 ? 25.232  100.178 25.152  1.00 27.24  ? 375 ASP F N   1 
ATOM   20720 C CA  . ASP F 1 375 ? 25.914  98.957  25.566  1.00 29.17  ? 375 ASP F CA  1 
ATOM   20721 C C   . ASP F 1 375 ? 27.131  99.243  26.433  1.00 30.77  ? 375 ASP F C   1 
ATOM   20722 O O   . ASP F 1 375 ? 27.654  98.338  27.091  1.00 30.10  ? 375 ASP F O   1 
ATOM   20723 C CB  . ASP F 1 375 ? 26.431  98.119  24.420  1.00 30.67  ? 375 ASP F CB  1 
ATOM   20724 C CG  . ASP F 1 375 ? 25.392  97.699  23.404  1.00 33.48  ? 375 ASP F CG  1 
ATOM   20725 O OD1 . ASP F 1 375 ? 24.452  96.947  23.775  1.00 36.44  ? 375 ASP F OD1 1 
ATOM   20726 O OD2 . ASP F 1 375 ? 25.552  98.150  22.263  1.00 32.56  ? 375 ASP F OD2 1 
ATOM   20727 N N   . ALA F 1 376 ? 27.566  100.503 26.420  1.00 31.01  ? 376 ALA F N   1 
ATOM   20728 C CA  . ALA F 1 376 ? 28.597  100.964 27.333  1.00 35.02  ? 376 ALA F CA  1 
ATOM   20729 C C   . ALA F 1 376 ? 28.196  100.796 28.808  1.00 33.46  ? 376 ALA F C   1 
ATOM   20730 O O   . ALA F 1 376 ? 29.062  100.505 29.645  1.00 29.46  ? 376 ALA F O   1 
ATOM   20731 C CB  . ALA F 1 376 ? 28.932  102.403 27.013  1.00 34.37  ? 376 ALA F CB  1 
ATOM   20732 N N   . HIS F 1 377 ? 26.900  100.991 29.120  1.00 32.26  ? 377 HIS F N   1 
ATOM   20733 C CA  . HIS F 1 377 ? 26.459  101.159 30.500  1.00 32.40  ? 377 HIS F CA  1 
ATOM   20734 C C   . HIS F 1 377 ? 25.791  99.912  31.096  1.00 33.36  ? 377 HIS F C   1 
ATOM   20735 O O   . HIS F 1 377 ? 25.677  99.787  32.307  1.00 38.62  ? 377 HIS F O   1 
ATOM   20736 C CB  . HIS F 1 377 ? 25.558  102.389 30.618  1.00 31.68  ? 377 HIS F CB  1 
ATOM   20737 C CG  . HIS F 1 377 ? 25.864  103.115 31.884  1.00 34.48  ? 377 HIS F CG  1 
ATOM   20738 N ND1 . HIS F 1 377 ? 25.980  102.463 33.098  1.00 33.25  ? 377 HIS F ND1 1 
ATOM   20739 C CD2 . HIS F 1 377 ? 26.121  104.411 32.120  1.00 33.96  ? 377 HIS F CD2 1 
ATOM   20740 C CE1 . HIS F 1 377 ? 26.276  103.348 34.038  1.00 35.69  ? 377 HIS F CE1 1 
ATOM   20741 N NE2 . HIS F 1 377 ? 26.375  104.544 33.466  1.00 37.48  ? 377 HIS F NE2 1 
ATOM   20742 N N   . SER F 1 378 ? 25.346  98.964  30.278  1.00 32.73  ? 378 SER F N   1 
ATOM   20743 C CA  . SER F 1 378 ? 24.397  97.979  30.766  1.00 30.19  ? 378 SER F CA  1 
ATOM   20744 C C   . SER F 1 378 ? 25.094  96.910  31.604  1.00 31.16  ? 378 SER F C   1 
ATOM   20745 O O   . SER F 1 378 ? 24.622  96.592  32.690  1.00 30.90  ? 378 SER F O   1 
ATOM   20746 C CB  . SER F 1 378 ? 23.596  97.391  29.626  1.00 28.69  ? 378 SER F CB  1 
ATOM   20747 O OG  . SER F 1 378 ? 24.414  96.813  28.626  1.00 27.82  ? 378 SER F OG  1 
ATOM   20748 N N   . GLY F 1 379 ? 26.206  96.368  31.087  1.00 32.42  ? 379 GLY F N   1 
ATOM   20749 C CA  . GLY F 1 379 ? 27.010  95.350  31.751  1.00 32.52  ? 379 GLY F CA  1 
ATOM   20750 C C   . GLY F 1 379 ? 27.348  95.696  33.211  1.00 30.50  ? 379 GLY F C   1 
ATOM   20751 O O   . GLY F 1 379 ? 27.225  94.839  34.082  1.00 25.55  ? 379 GLY F O   1 
ATOM   20752 N N   . VAL F 1 380 ? 27.764  96.938  33.496  1.00 28.33  ? 380 VAL F N   1 
ATOM   20753 C CA  . VAL F 1 380 ? 28.237  97.249  34.837  1.00 32.37  ? 380 VAL F CA  1 
ATOM   20754 C C   . VAL F 1 380 ? 27.076  97.151  35.826  1.00 29.66  ? 380 VAL F C   1 
ATOM   20755 O O   . VAL F 1 380 ? 27.279  96.729  36.962  1.00 28.90  ? 380 VAL F O   1 
ATOM   20756 C CB  . VAL F 1 380 ? 29.002  98.581  34.998  1.00 35.92  ? 380 VAL F CB  1 
ATOM   20757 C CG1 . VAL F 1 380 ? 30.317  98.531  34.215  1.00 38.28  ? 380 VAL F CG1 1 
ATOM   20758 C CG2 . VAL F 1 380 ? 28.176  99.812  34.617  1.00 35.26  ? 380 VAL F CG2 1 
ATOM   20759 N N   . LEU F 1 381 ? 25.879  97.544  35.392  1.00 26.36  ? 381 LEU F N   1 
ATOM   20760 C CA  . LEU F 1 381 ? 24.710  97.467  36.252  1.00 27.41  ? 381 LEU F CA  1 
ATOM   20761 C C   . LEU F 1 381 ? 24.475  96.018  36.673  1.00 27.09  ? 381 LEU F C   1 
ATOM   20762 O O   . LEU F 1 381 ? 24.340  95.726  37.849  1.00 28.63  ? 381 LEU F O   1 
ATOM   20763 C CB  . LEU F 1 381 ? 23.501  98.088  35.557  1.00 27.62  ? 381 LEU F CB  1 
ATOM   20764 C CG  . LEU F 1 381 ? 23.671  99.560  35.152  1.00 30.21  ? 381 LEU F CG  1 
ATOM   20765 C CD1 . LEU F 1 381 ? 22.382  100.205 34.663  1.00 31.15  ? 381 LEU F CD1 1 
ATOM   20766 C CD2 . LEU F 1 381 ? 24.228  100.366 36.311  1.00 31.87  ? 381 LEU F CD2 1 
ATOM   20767 N N   . LEU F 1 382 ? 24.496  95.091  35.728  1.00 28.04  ? 382 LEU F N   1 
ATOM   20768 C CA  . LEU F 1 382 ? 24.266  93.692  36.051  1.00 29.73  ? 382 LEU F CA  1 
ATOM   20769 C C   . LEU F 1 382 ? 25.361  93.123  36.950  1.00 29.42  ? 382 LEU F C   1 
ATOM   20770 O O   . LEU F 1 382 ? 25.094  92.340  37.857  1.00 27.64  ? 382 LEU F O   1 
ATOM   20771 C CB  . LEU F 1 382 ? 24.196  92.915  34.744  1.00 29.24  ? 382 LEU F CB  1 
ATOM   20772 C CG  . LEU F 1 382 ? 23.039  93.264  33.810  1.00 30.86  ? 382 LEU F CG  1 
ATOM   20773 C CD1 . LEU F 1 382 ? 23.196  92.506  32.489  1.00 33.23  ? 382 LEU F CD1 1 
ATOM   20774 C CD2 . LEU F 1 382 ? 21.725  92.947  34.444  1.00 29.20  ? 382 LEU F CD2 1 
ATOM   20775 N N   . TRP F 1 383 ? 26.605  93.485  36.641  1.00 31.83  ? 383 TRP F N   1 
ATOM   20776 C CA  . TRP F 1 383 ? 27.774  92.959  37.325  1.00 33.39  ? 383 TRP F CA  1 
ATOM   20777 C C   . TRP F 1 383 ? 27.725  93.266  38.825  1.00 35.26  ? 383 TRP F C   1 
ATOM   20778 O O   . TRP F 1 383 ? 28.097  92.425  39.648  1.00 38.31  ? 383 TRP F O   1 
ATOM   20779 C CB  . TRP F 1 383 ? 29.021  93.568  36.673  1.00 32.19  ? 383 TRP F CB  1 
ATOM   20780 C CG  . TRP F 1 383 ? 30.318  93.129  37.290  1.00 35.32  ? 383 TRP F CG  1 
ATOM   20781 C CD1 . TRP F 1 383 ? 30.876  93.580  38.452  1.00 33.61  ? 383 TRP F CD1 1 
ATOM   20782 C CD2 . TRP F 1 383 ? 31.237  92.169  36.732  1.00 33.85  ? 383 TRP F CD2 1 
ATOM   20783 N NE1 . TRP F 1 383 ? 32.071  92.959  38.660  1.00 33.95  ? 383 TRP F NE1 1 
ATOM   20784 C CE2 . TRP F 1 383 ? 32.322  92.088  37.626  1.00 36.73  ? 383 TRP F CE2 1 
ATOM   20785 C CE3 . TRP F 1 383 ? 31.239  91.371  35.587  1.00 31.61  ? 383 TRP F CE3 1 
ATOM   20786 C CZ2 . TRP F 1 383 ? 33.411  91.242  37.391  1.00 36.96  ? 383 TRP F CZ2 1 
ATOM   20787 C CZ3 . TRP F 1 383 ? 32.316  90.543  35.350  1.00 34.76  ? 383 TRP F CZ3 1 
ATOM   20788 C CH2 . TRP F 1 383 ? 33.394  90.477  36.241  1.00 35.19  ? 383 TRP F CH2 1 
ATOM   20789 N N   . HIS F 1 384 ? 27.322  94.501  39.149  1.00 31.79  ? 384 HIS F N   1 
ATOM   20790 C CA  . HIS F 1 384 ? 27.119  94.944  40.513  1.00 32.90  ? 384 HIS F CA  1 
ATOM   20791 C C   . HIS F 1 384 ? 26.242  93.966  41.301  1.00 34.02  ? 384 HIS F C   1 
ATOM   20792 O O   . HIS F 1 384 ? 26.571  93.654  42.429  1.00 34.10  ? 384 HIS F O   1 
ATOM   20793 C CB  . HIS F 1 384 ? 26.486  96.334  40.499  1.00 34.17  ? 384 HIS F CB  1 
ATOM   20794 C CG  . HIS F 1 384 ? 26.226  96.872  41.858  1.00 39.20  ? 384 HIS F CG  1 
ATOM   20795 N ND1 . HIS F 1 384 ? 27.151  97.620  42.559  1.00 39.14  ? 384 HIS F ND1 1 
ATOM   20796 C CD2 . HIS F 1 384 ? 25.128  96.791  42.633  1.00 40.11  ? 384 HIS F CD2 1 
ATOM   20797 C CE1 . HIS F 1 384 ? 26.634  97.943  43.738  1.00 41.09  ? 384 HIS F CE1 1 
ATOM   20798 N NE2 . HIS F 1 384 ? 25.399  97.466  43.792  1.00 43.16  ? 384 HIS F NE2 1 
ATOM   20799 N N   . TYR F 1 385 ? 25.137  93.475  40.711  1.00 32.40  ? 385 TYR F N   1 
ATOM   20800 C CA  . TYR F 1 385 ? 24.159  92.650  41.416  1.00 30.52  ? 385 TYR F CA  1 
ATOM   20801 C C   . TYR F 1 385 ? 24.558  91.178  41.318  1.00 29.76  ? 385 TYR F C   1 
ATOM   20802 O O   . TYR F 1 385 ? 23.760  90.297  41.614  1.00 30.58  ? 385 TYR F O   1 
ATOM   20803 C CB  . TYR F 1 385 ? 22.726  92.947  40.934  1.00 26.87  ? 385 TYR F CB  1 
ATOM   20804 C CG  . TYR F 1 385 ? 22.272  94.353  41.318  1.00 27.60  ? 385 TYR F CG  1 
ATOM   20805 C CD1 . TYR F 1 385 ? 21.846  94.633  42.614  1.00 26.51  ? 385 TYR F CD1 1 
ATOM   20806 C CD2 . TYR F 1 385 ? 22.307  95.418  40.413  1.00 27.01  ? 385 TYR F CD2 1 
ATOM   20807 C CE1 . TYR F 1 385 ? 21.445  95.907  42.988  1.00 27.23  ? 385 TYR F CE1 1 
ATOM   20808 C CE2 . TYR F 1 385 ? 21.910  96.702  40.777  1.00 26.45  ? 385 TYR F CE2 1 
ATOM   20809 C CZ  . TYR F 1 385 ? 21.505  96.951  42.077  1.00 29.36  ? 385 TYR F CZ  1 
ATOM   20810 O OH  . TYR F 1 385 ? 21.112  98.196  42.480  1.00 32.40  ? 385 TYR F OH  1 
ATOM   20811 N N   . GLY F 1 386 ? 25.799  90.903  40.923  1.00 27.07  ? 386 GLY F N   1 
ATOM   20812 C CA  . GLY F 1 386 ? 26.254  89.531  40.867  1.00 26.65  ? 386 GLY F CA  1 
ATOM   20813 C C   . GLY F 1 386 ? 25.839  88.809  39.587  1.00 28.32  ? 386 GLY F C   1 
ATOM   20814 O O   . GLY F 1 386 ? 25.867  87.587  39.561  1.00 31.68  ? 386 GLY F O   1 
ATOM   20815 N N   . ILE F 1 387 ? 25.487  89.523  38.507  1.00 31.85  ? 387 ILE F N   1 
ATOM   20816 C CA  . ILE F 1 387 ? 25.338  88.859  37.213  1.00 31.46  ? 387 ILE F CA  1 
ATOM   20817 C C   . ILE F 1 387 ? 26.584  89.225  36.428  1.00 32.94  ? 387 ILE F C   1 
ATOM   20818 O O   . ILE F 1 387 ? 26.617  90.281  35.807  1.00 36.04  ? 387 ILE F O   1 
ATOM   20819 C CB  . ILE F 1 387 ? 24.051  89.224  36.436  1.00 32.80  ? 387 ILE F CB  1 
ATOM   20820 C CG1 . ILE F 1 387 ? 22.766  88.812  37.173  1.00 36.07  ? 387 ILE F CG1 1 
ATOM   20821 C CG2 . ILE F 1 387 ? 24.065  88.609  35.034  1.00 33.50  ? 387 ILE F CG2 1 
ATOM   20822 C CD1 . ILE F 1 387 ? 21.894  89.966  37.614  1.00 38.08  ? 387 ILE F CD1 1 
ATOM   20823 N N   . ARG F 1 388 ? 27.596  88.357  36.504  1.00 32.43  ? 388 ARG F N   1 
ATOM   20824 C CA  . ARG F 1 388 ? 28.924  88.684  36.028  1.00 36.68  ? 388 ARG F CA  1 
ATOM   20825 C C   . ARG F 1 388 ? 29.259  87.929  34.740  1.00 32.24  ? 388 ARG F C   1 
ATOM   20826 O O   . ARG F 1 388 ? 30.343  88.112  34.214  1.00 31.47  ? 388 ARG F O   1 
ATOM   20827 C CB  . ARG F 1 388 ? 29.950  88.340  37.110  1.00 42.87  ? 388 ARG F CB  1 
ATOM   20828 C CG  . ARG F 1 388 ? 29.937  89.158  38.393  1.00 49.56  ? 388 ARG F CG  1 
ATOM   20829 C CD  . ARG F 1 388 ? 30.705  88.368  39.467  1.00 57.13  ? 388 ARG F CD  1 
ATOM   20830 N NE  . ARG F 1 388 ? 31.368  89.219  40.462  1.00 63.72  ? 388 ARG F NE  1 
ATOM   20831 C CZ  . ARG F 1 388 ? 32.697  89.316  40.634  1.00 65.43  ? 388 ARG F CZ  1 
ATOM   20832 N NH1 . ARG F 1 388 ? 33.548  88.499  40.018  1.00 59.22  ? 388 ARG F NH1 1 
ATOM   20833 N NH2 . ARG F 1 388 ? 33.182  90.245  41.444  1.00 68.57  ? 388 ARG F NH2 1 
ATOM   20834 N N   . GLU F 1 389 ? 28.332  87.121  34.219  1.00 28.54  ? 389 GLU F N   1 
ATOM   20835 C CA  . GLU F 1 389 ? 28.582  86.327  33.030  1.00 30.02  ? 389 GLU F CA  1 
ATOM   20836 C C   . GLU F 1 389 ? 28.284  87.176  31.788  1.00 31.02  ? 389 GLU F C   1 
ATOM   20837 O O   . GLU F 1 389 ? 27.162  87.221  31.299  1.00 30.59  ? 389 GLU F O   1 
ATOM   20838 C CB  . GLU F 1 389 ? 27.757  85.046  33.122  1.00 31.57  ? 389 GLU F CB  1 
ATOM   20839 C CG  . GLU F 1 389 ? 27.975  84.261  34.416  1.00 31.20  ? 389 GLU F CG  1 
ATOM   20840 C CD  . GLU F 1 389 ? 27.225  84.687  35.683  1.00 30.33  ? 389 GLU F CD  1 
ATOM   20841 O OE1 . GLU F 1 389 ? 27.439  83.984  36.676  1.00 28.41  ? 389 GLU F OE1 1 
ATOM   20842 O OE2 . GLU F 1 389 ? 26.456  85.672  35.736  1.00 28.87  ? 389 GLU F OE2 1 
ATOM   20843 N N   . TYR F 1 390 ? 29.316  87.842  31.262  1.00 31.53  ? 390 TYR F N   1 
ATOM   20844 C CA  . TYR F 1 390 ? 29.150  88.840  30.217  1.00 32.04  ? 390 TYR F CA  1 
ATOM   20845 C C   . TYR F 1 390 ? 28.765  88.198  28.877  1.00 28.24  ? 390 TYR F C   1 
ATOM   20846 O O   . TYR F 1 390 ? 28.185  88.877  28.047  1.00 27.52  ? 390 TYR F O   1 
ATOM   20847 C CB  . TYR F 1 390 ? 30.368  89.786  30.152  1.00 37.19  ? 390 TYR F CB  1 
ATOM   20848 C CG  . TYR F 1 390 ? 31.776  89.193  30.178  1.00 36.71  ? 390 TYR F CG  1 
ATOM   20849 C CD1 . TYR F 1 390 ? 32.280  88.524  29.074  1.00 36.20  ? 390 TYR F CD1 1 
ATOM   20850 C CD2 . TYR F 1 390 ? 32.608  89.335  31.285  1.00 36.88  ? 390 TYR F CD2 1 
ATOM   20851 C CE1 . TYR F 1 390 ? 33.547  87.975  29.075  1.00 40.67  ? 390 TYR F CE1 1 
ATOM   20852 C CE2 . TYR F 1 390 ? 33.878  88.788  31.303  1.00 38.57  ? 390 TYR F CE2 1 
ATOM   20853 C CZ  . TYR F 1 390 ? 34.347  88.103  30.194  1.00 43.83  ? 390 TYR F CZ  1 
ATOM   20854 O OH  . TYR F 1 390 ? 35.596  87.555  30.143  1.00 47.91  ? 390 TYR F OH  1 
ATOM   20855 N N   . ASP F 1 391 ? 29.013  86.903  28.665  1.00 28.44  ? 391 ASP F N   1 
ATOM   20856 C CA  . ASP F 1 391 ? 28.594  86.244  27.436  1.00 29.52  ? 391 ASP F CA  1 
ATOM   20857 C C   . ASP F 1 391 ? 27.075  86.110  27.356  1.00 29.41  ? 391 ASP F C   1 
ATOM   20858 O O   . ASP F 1 391 ? 26.524  85.835  26.296  1.00 30.52  ? 391 ASP F O   1 
ATOM   20859 C CB  . ASP F 1 391 ? 29.215  84.868  27.289  1.00 32.74  ? 391 ASP F CB  1 
ATOM   20860 C CG  . ASP F 1 391 ? 30.700  84.861  26.940  1.00 38.66  ? 391 ASP F CG  1 
ATOM   20861 O OD1 . ASP F 1 391 ? 31.242  85.944  26.564  1.00 36.15  ? 391 ASP F OD1 1 
ATOM   20862 O OD2 . ASP F 1 391 ? 31.317  83.772  27.084  1.00 42.39  ? 391 ASP F OD2 1 
ATOM   20863 N N   . PHE F 1 392 ? 26.388  86.355  28.472  1.00 29.01  ? 392 PHE F N   1 
ATOM   20864 C CA  . PHE F 1 392 ? 24.942  86.198  28.529  1.00 27.75  ? 392 PHE F CA  1 
ATOM   20865 C C   . PHE F 1 392 ? 24.258  87.538  28.278  1.00 26.19  ? 392 PHE F C   1 
ATOM   20866 O O   . PHE F 1 392 ? 23.051  87.596  28.123  1.00 26.69  ? 392 PHE F O   1 
ATOM   20867 C CB  . PHE F 1 392 ? 24.586  85.606  29.902  1.00 26.57  ? 392 PHE F CB  1 
ATOM   20868 C CG  . PHE F 1 392 ? 23.124  85.248  30.098  1.00 24.26  ? 392 PHE F CG  1 
ATOM   20869 C CD1 . PHE F 1 392 ? 22.608  84.079  29.561  1.00 25.27  ? 392 PHE F CD1 1 
ATOM   20870 C CD2 . PHE F 1 392 ? 22.277  86.088  30.801  1.00 22.54  ? 392 PHE F CD2 1 
ATOM   20871 C CE1 . PHE F 1 392 ? 21.275  83.760  29.735  1.00 24.10  ? 392 PHE F CE1 1 
ATOM   20872 C CE2 . PHE F 1 392 ? 20.945  85.764  30.983  1.00 23.09  ? 392 PHE F CE2 1 
ATOM   20873 C CZ  . PHE F 1 392 ? 20.446  84.605  30.439  1.00 23.76  ? 392 PHE F CZ  1 
ATOM   20874 N N   . TYR F 1 393 ? 25.018  88.626  28.271  1.00 26.64  ? 393 TYR F N   1 
ATOM   20875 C CA  . TYR F 1 393 ? 24.392  89.933  28.365  1.00 31.43  ? 393 TYR F CA  1 
ATOM   20876 C C   . TYR F 1 393 ? 23.535  90.231  27.126  1.00 29.03  ? 393 TYR F C   1 
ATOM   20877 O O   . TYR F 1 393 ? 22.544  90.960  27.227  1.00 29.68  ? 393 TYR F O   1 
ATOM   20878 C CB  . TYR F 1 393 ? 25.475  90.993  28.602  1.00 33.79  ? 393 TYR F CB  1 
ATOM   20879 C CG  . TYR F 1 393 ? 26.141  91.055  29.969  1.00 34.33  ? 393 TYR F CG  1 
ATOM   20880 C CD1 . TYR F 1 393 ? 25.758  90.231  31.019  1.00 32.17  ? 393 TYR F CD1 1 
ATOM   20881 C CD2 . TYR F 1 393 ? 27.123  92.011  30.216  1.00 34.74  ? 393 TYR F CD2 1 
ATOM   20882 C CE1 . TYR F 1 393 ? 26.354  90.331  32.259  1.00 31.14  ? 393 TYR F CE1 1 
ATOM   20883 C CE2 . TYR F 1 393 ? 27.719  92.130  31.454  1.00 31.72  ? 393 TYR F CE2 1 
ATOM   20884 C CZ  . TYR F 1 393 ? 27.331  91.280  32.472  1.00 32.48  ? 393 TYR F CZ  1 
ATOM   20885 O OH  . TYR F 1 393 ? 27.955  91.346  33.676  1.00 35.38  ? 393 TYR F OH  1 
ATOM   20886 N N   . THR F 1 394 ? 23.911  89.679  25.964  1.00 26.87  ? 394 THR F N   1 
ATOM   20887 C CA  . THR F 1 394 ? 23.194  89.947  24.726  1.00 24.44  ? 394 THR F CA  1 
ATOM   20888 C C   . THR F 1 394 ? 21.881  89.160  24.684  1.00 24.46  ? 394 THR F C   1 
ATOM   20889 O O   . THR F 1 394 ? 20.928  89.576  24.038  1.00 26.36  ? 394 THR F O   1 
ATOM   20890 C CB  . THR F 1 394 ? 24.103  89.663  23.527  1.00 28.24  ? 394 THR F CB  1 
ATOM   20891 O OG1 . THR F 1 394 ? 25.356  90.349  23.677  1.00 27.52  ? 394 THR F OG1 1 
ATOM   20892 C CG2 . THR F 1 394 ? 23.482  90.130  22.216  1.00 28.23  ? 394 THR F CG2 1 
ATOM   20893 N N   . VAL F 1 395 ? 21.780  88.045  25.415  1.00 24.40  ? 395 VAL F N   1 
ATOM   20894 C CA  . VAL F 1 395 ? 20.501  87.379  25.597  1.00 23.13  ? 395 VAL F CA  1 
ATOM   20895 C C   . VAL F 1 395 ? 19.510  88.278  26.335  1.00 23.68  ? 395 VAL F C   1 
ATOM   20896 O O   . VAL F 1 395 ? 18.339  88.340  25.968  1.00 21.27  ? 395 VAL F O   1 
ATOM   20897 C CB  . VAL F 1 395 ? 20.617  86.020  26.304  1.00 24.47  ? 395 VAL F CB  1 
ATOM   20898 C CG1 . VAL F 1 395 ? 19.233  85.455  26.602  1.00 24.68  ? 395 VAL F CG1 1 
ATOM   20899 C CG2 . VAL F 1 395 ? 21.437  85.029  25.481  1.00 24.67  ? 395 VAL F CG2 1 
ATOM   20900 N N   . LEU F 1 396 ? 19.948  88.981  27.380  1.00 25.44  ? 396 LEU F N   1 
ATOM   20901 C CA  . LEU F 1 396 ? 19.022  89.864  28.077  1.00 25.98  ? 396 LEU F CA  1 
ATOM   20902 C C   . LEU F 1 396 ? 18.506  90.917  27.091  1.00 26.05  ? 396 LEU F C   1 
ATOM   20903 O O   . LEU F 1 396 ? 17.319  91.278  27.073  1.00 24.21  ? 396 LEU F O   1 
ATOM   20904 C CB  . LEU F 1 396 ? 19.700  90.463  29.313  1.00 27.67  ? 396 LEU F CB  1 
ATOM   20905 C CG  . LEU F 1 396 ? 19.938  89.481  30.476  1.00 29.87  ? 396 LEU F CG  1 
ATOM   20906 C CD1 . LEU F 1 396 ? 20.814  90.104  31.521  1.00 30.06  ? 396 LEU F CD1 1 
ATOM   20907 C CD2 . LEU F 1 396 ? 18.646  88.930  31.131  1.00 29.29  ? 396 LEU F CD2 1 
ATOM   20908 N N   . PHE F 1 397 ? 19.423  91.405  26.256  1.00 24.10  ? 397 PHE F N   1 
ATOM   20909 C CA  . PHE F 1 397 ? 19.072  92.393  25.260  1.00 25.65  ? 397 PHE F CA  1 
ATOM   20910 C C   . PHE F 1 397 ? 17.981  91.828  24.356  1.00 25.83  ? 397 PHE F C   1 
ATOM   20911 O O   . PHE F 1 397 ? 17.007  92.518  24.039  1.00 25.40  ? 397 PHE F O   1 
ATOM   20912 C CB  . PHE F 1 397 ? 20.320  92.728  24.442  1.00 25.90  ? 397 PHE F CB  1 
ATOM   20913 C CG  . PHE F 1 397 ? 20.252  93.977  23.585  1.00 23.28  ? 397 PHE F CG  1 
ATOM   20914 C CD1 . PHE F 1 397 ? 19.045  94.487  23.134  1.00 22.35  ? 397 PHE F CD1 1 
ATOM   20915 C CD2 . PHE F 1 397 ? 21.427  94.626  23.236  1.00 23.33  ? 397 PHE F CD2 1 
ATOM   20916 C CE1 . PHE F 1 397 ? 19.025  95.618  22.343  1.00 23.87  ? 397 PHE F CE1 1 
ATOM   20917 C CE2 . PHE F 1 397 ? 21.410  95.758  22.454  1.00 22.84  ? 397 PHE F CE2 1 
ATOM   20918 C CZ  . PHE F 1 397 ? 20.207  96.251  22.002  1.00 25.74  ? 397 PHE F CZ  1 
ATOM   20919 N N   . GLY F 1 398 ? 18.167  90.574  23.939  1.00 24.19  ? 398 GLY F N   1 
ATOM   20920 C CA  . GLY F 1 398 ? 17.226  89.911  23.048  1.00 25.87  ? 398 GLY F CA  1 
ATOM   20921 C C   . GLY F 1 398 ? 15.813  89.816  23.628  1.00 26.18  ? 398 GLY F C   1 
ATOM   20922 O O   . GLY F 1 398 ? 14.834  90.102  22.944  1.00 28.36  ? 398 GLY F O   1 
ATOM   20923 N N   . VAL F 1 399 ? 15.703  89.357  24.881  1.00 26.35  ? 399 VAL F N   1 
ATOM   20924 C CA  . VAL F 1 399 ? 14.424  89.261  25.552  1.00 25.33  ? 399 VAL F CA  1 
ATOM   20925 C C   . VAL F 1 399 ? 13.720  90.613  25.424  1.00 26.54  ? 399 VAL F C   1 
ATOM   20926 O O   . VAL F 1 399 ? 12.579  90.680  24.967  1.00 29.28  ? 399 VAL F O   1 
ATOM   20927 C CB  . VAL F 1 399 ? 14.632  88.816  27.013  1.00 28.95  ? 399 VAL F CB  1 
ATOM   20928 C CG1 . VAL F 1 399 ? 13.348  88.861  27.820  1.00 30.36  ? 399 VAL F CG1 1 
ATOM   20929 C CG2 . VAL F 1 399 ? 15.234  87.422  27.124  1.00 28.18  ? 399 VAL F CG2 1 
ATOM   20930 N N   . SER F 1 400 ? 14.423  91.703  25.744  1.00 25.96  ? 400 SER F N   1 
ATOM   20931 C CA  . SER F 1 400 ? 13.842  93.037  25.664  1.00 27.38  ? 400 SER F CA  1 
ATOM   20932 C C   . SER F 1 400 ? 13.408  93.353  24.231  1.00 28.12  ? 400 SER F C   1 
ATOM   20933 O O   . SER F 1 400 ? 12.277  93.795  23.996  1.00 27.08  ? 400 SER F O   1 
ATOM   20934 C CB  . SER F 1 400 ? 14.806  94.094  26.186  1.00 28.07  ? 400 SER F CB  1 
ATOM   20935 O OG  . SER F 1 400 ? 14.416  95.409  25.811  1.00 26.35  ? 400 SER F OG  1 
ATOM   20936 N N   . ARG F 1 401 ? 14.320  93.119  23.283  1.00 25.83  ? 401 ARG F N   1 
ATOM   20937 C CA  . ARG F 1 401 ? 14.166  93.598  21.918  1.00 27.15  ? 401 ARG F CA  1 
ATOM   20938 C C   . ARG F 1 401 ? 13.070  92.838  21.176  1.00 25.47  ? 401 ARG F C   1 
ATOM   20939 O O   . ARG F 1 401 ? 12.590  93.295  20.135  1.00 27.18  ? 401 ARG F O   1 
ATOM   20940 C CB  . ARG F 1 401 ? 15.509  93.505  21.173  1.00 27.77  ? 401 ARG F CB  1 
ATOM   20941 C CG  . ARG F 1 401 ? 15.534  93.903  19.703  1.00 26.59  ? 401 ARG F CG  1 
ATOM   20942 C CD  . ARG F 1 401 ? 14.945  95.266  19.421  1.00 26.55  ? 401 ARG F CD  1 
ATOM   20943 N NE  . ARG F 1 401 ? 15.590  96.391  20.098  1.00 28.89  ? 401 ARG F NE  1 
ATOM   20944 C CZ  . ARG F 1 401 ? 16.667  97.040  19.702  1.00 29.12  ? 401 ARG F CZ  1 
ATOM   20945 N NH1 . ARG F 1 401 ? 17.292  96.678  18.591  1.00 27.34  ? 401 ARG F NH1 1 
ATOM   20946 N NH2 . ARG F 1 401 ? 17.093  98.067  20.424  1.00 30.96  ? 401 ARG F NH2 1 
ATOM   20947 N N   . ALA F 1 402 ? 12.703  91.674  21.695  1.00 23.80  ? 402 ALA F N   1 
ATOM   20948 C CA  . ALA F 1 402 ? 11.545  90.947  21.202  1.00 26.36  ? 402 ALA F CA  1 
ATOM   20949 C C   . ALA F 1 402 ? 10.268  91.801  21.273  1.00 28.27  ? 402 ALA F C   1 
ATOM   20950 O O   . ALA F 1 402 ? 9.317   91.611  20.491  1.00 23.04  ? 402 ALA F O   1 
ATOM   20951 C CB  . ALA F 1 402 ? 11.407  89.663  22.006  1.00 26.54  ? 402 ALA F CB  1 
ATOM   20952 N N   . LEU F 1 403 ? 10.221  92.709  22.265  1.00 30.42  ? 403 LEU F N   1 
ATOM   20953 C CA  . LEU F 1 403 ? 9.078   93.597  22.426  1.00 30.04  ? 403 LEU F CA  1 
ATOM   20954 C C   . LEU F 1 403 ? 8.914   94.415  21.145  1.00 31.50  ? 403 LEU F C   1 
ATOM   20955 O O   . LEU F 1 403 ? 7.846   94.411  20.538  1.00 31.34  ? 403 LEU F O   1 
ATOM   20956 C CB  . LEU F 1 403 ? 9.244   94.507  23.640  1.00 27.70  ? 403 LEU F CB  1 
ATOM   20957 C CG  . LEU F 1 403 ? 9.260   93.808  24.996  1.00 27.03  ? 403 LEU F CG  1 
ATOM   20958 C CD1 . LEU F 1 403 ? 9.742   94.822  26.008  1.00 29.62  ? 403 LEU F CD1 1 
ATOM   20959 C CD2 . LEU F 1 403 ? 7.915   93.259  25.404  1.00 24.38  ? 403 LEU F CD2 1 
ATOM   20960 N N   . GLY F 1 404 ? 9.973   95.137  20.761  1.00 28.42  ? 404 GLY F N   1 
ATOM   20961 C CA  . GLY F 1 404 ? 9.939   95.911  19.535  1.00 28.16  ? 404 GLY F CA  1 
ATOM   20962 C C   . GLY F 1 404 ? 9.722   95.020  18.312  1.00 25.95  ? 404 GLY F C   1 
ATOM   20963 O O   . GLY F 1 404 ? 8.923   95.340  17.458  1.00 27.35  ? 404 GLY F O   1 
ATOM   20964 N N   . CYS F 1 405 ? 10.407  93.884  18.235  1.00 26.01  ? 405 CYS F N   1 
ATOM   20965 C CA  . CYS F 1 405 ? 10.293  93.034  17.064  1.00 28.34  ? 405 CYS F CA  1 
ATOM   20966 C C   . CYS F 1 405 ? 8.854   92.537  16.903  1.00 30.50  ? 405 CYS F C   1 
ATOM   20967 O O   . CYS F 1 405 ? 8.360   92.465  15.765  1.00 31.29  ? 405 CYS F O   1 
ATOM   20968 C CB  . CYS F 1 405 ? 11.302  91.887  17.085  1.00 28.74  ? 405 CYS F CB  1 
ATOM   20969 S SG  . CYS F 1 405 ? 12.996  92.453  16.792  1.00 27.03  ? 405 CYS F SG  1 
ATOM   20970 N N   . THR F 1 406 ? 8.202   92.166  18.021  1.00 28.55  ? 406 THR F N   1 
ATOM   20971 C CA  . THR F 1 406 ? 6.830   91.674  17.957  1.00 27.43  ? 406 THR F CA  1 
ATOM   20972 C C   . THR F 1 406 ? 5.913   92.832  17.569  1.00 26.12  ? 406 THR F C   1 
ATOM   20973 O O   . THR F 1 406 ? 5.027   92.658  16.737  1.00 27.87  ? 406 THR F O   1 
ATOM   20974 C CB  . THR F 1 406 ? 6.341   90.967  19.224  1.00 25.84  ? 406 THR F CB  1 
ATOM   20975 O OG1 . THR F 1 406 ? 6.533   91.793  20.370  1.00 27.38  ? 406 THR F OG1 1 
ATOM   20976 C CG2 . THR F 1 406 ? 7.002   89.621  19.428  1.00 25.21  ? 406 THR F CG2 1 
ATOM   20977 N N   . ALA F 1 407 ? 6.128   94.019  18.135  1.00 27.03  ? 407 ALA F N   1 
ATOM   20978 C CA  . ALA F 1 407 ? 5.203   95.109  17.858  1.00 32.32  ? 407 ALA F CA  1 
ATOM   20979 C C   . ALA F 1 407 ? 5.245   95.456  16.370  1.00 31.30  ? 407 ALA F C   1 
ATOM   20980 O O   . ALA F 1 407 ? 4.194   95.535  15.755  1.00 33.10  ? 407 ALA F O   1 
ATOM   20981 C CB  . ALA F 1 407 ? 5.470   96.302  18.745  1.00 34.55  ? 407 ALA F CB  1 
ATOM   20982 N N   . GLN F 1 408 ? 6.450   95.561  15.787  1.00 32.00  ? 408 GLN F N   1 
ATOM   20983 C CA  . GLN F 1 408 ? 6.644   95.856  14.367  1.00 30.09  ? 408 GLN F CA  1 
ATOM   20984 C C   . GLN F 1 408 ? 6.069   94.784  13.437  1.00 30.50  ? 408 GLN F C   1 
ATOM   20985 O O   . GLN F 1 408 ? 5.358   95.111  12.489  1.00 26.57  ? 408 GLN F O   1 
ATOM   20986 C CB  . GLN F 1 408 ? 8.125   96.043  14.054  1.00 28.31  ? 408 GLN F CB  1 
ATOM   20987 C CG  . GLN F 1 408 ? 8.664   97.328  14.666  1.00 30.46  ? 408 GLN F CG  1 
ATOM   20988 C CD  . GLN F 1 408 ? 10.063  97.674  14.225  1.00 31.40  ? 408 GLN F CD  1 
ATOM   20989 O OE1 . GLN F 1 408 ? 10.836  98.278  14.975  1.00 34.17  ? 408 GLN F OE1 1 
ATOM   20990 N NE2 . GLN F 1 408 ? 10.379  97.346  12.986  1.00 31.29  ? 408 GLN F NE2 1 
ATOM   20991 N N   . ALA F 1 409 ? 6.378   93.509  13.695  1.00 34.01  ? 409 ALA F N   1 
ATOM   20992 C CA  . ALA F 1 409 ? 5.880   92.426  12.852  1.00 31.72  ? 409 ALA F CA  1 
ATOM   20993 C C   . ALA F 1 409 ? 4.350   92.416  12.819  1.00 35.62  ? 409 ALA F C   1 
ATOM   20994 O O   . ALA F 1 409 ? 3.779   92.276  11.739  1.00 36.66  ? 409 ALA F O   1 
ATOM   20995 C CB  . ALA F 1 409 ? 6.409   91.094  13.305  1.00 27.66  ? 409 ALA F CB  1 
ATOM   20996 N N   . ILE F 1 410 ? 3.694   92.585  13.981  1.00 32.52  ? 410 ILE F N   1 
ATOM   20997 C CA  . ILE F 1 410 ? 2.235   92.604  14.056  1.00 32.76  ? 410 ILE F CA  1 
ATOM   20998 C C   . ILE F 1 410 ? 1.685   93.743  13.191  1.00 31.58  ? 410 ILE F C   1 
ATOM   20999 O O   . ILE F 1 410 ? 0.782   93.551  12.384  1.00 29.04  ? 410 ILE F O   1 
ATOM   21000 C CB  . ILE F 1 410 ? 1.754   92.705  15.519  1.00 31.79  ? 410 ILE F CB  1 
ATOM   21001 C CG1 . ILE F 1 410 ? 2.048   91.419  16.304  1.00 30.12  ? 410 ILE F CG1 1 
ATOM   21002 C CG2 . ILE F 1 410 ? 0.267   93.047  15.580  1.00 32.16  ? 410 ILE F CG2 1 
ATOM   21003 C CD1 . ILE F 1 410 ? 2.057   91.574  17.817  1.00 30.10  ? 410 ILE F CD1 1 
ATOM   21004 N N   . LEU F 1 411 ? 2.270   94.932  13.330  1.00 32.29  ? 411 LEU F N   1 
ATOM   21005 C CA  . LEU F 1 411 ? 1.751   96.116  12.664  1.00 31.59  ? 411 LEU F CA  1 
ATOM   21006 C C   . LEU F 1 411 ? 1.896   95.987  11.156  1.00 30.28  ? 411 LEU F C   1 
ATOM   21007 O O   . LEU F 1 411 ? 0.974   96.244  10.398  1.00 35.02  ? 411 LEU F O   1 
ATOM   21008 C CB  . LEU F 1 411 ? 2.464   97.360  13.197  1.00 29.13  ? 411 LEU F CB  1 
ATOM   21009 C CG  . LEU F 1 411 ? 2.085   97.766  14.621  1.00 30.08  ? 411 LEU F CG  1 
ATOM   21010 C CD1 . LEU F 1 411 ? 3.022   98.838  15.143  1.00 32.26  ? 411 LEU F CD1 1 
ATOM   21011 C CD2 . LEU F 1 411 ? 0.625   98.235  14.694  1.00 29.33  ? 411 LEU F CD2 1 
ATOM   21012 N N   . VAL F 1 412 ? 3.084   95.591  10.728  1.00 33.15  ? 412 VAL F N   1 
ATOM   21013 C CA  . VAL F 1 412 ? 3.432   95.586  9.319   1.00 31.91  ? 412 VAL F CA  1 
ATOM   21014 C C   . VAL F 1 412 ? 2.658   94.490  8.570   1.00 29.15  ? 412 VAL F C   1 
ATOM   21015 O O   . VAL F 1 412 ? 2.381   94.616  7.378   1.00 29.10  ? 412 VAL F O   1 
ATOM   21016 C CB  . VAL F 1 412 ? 4.973   95.497  9.279   1.00 33.17  ? 412 VAL F CB  1 
ATOM   21017 C CG1 . VAL F 1 412 ? 5.525   94.779  8.071   1.00 38.01  ? 412 VAL F CG1 1 
ATOM   21018 C CG2 . VAL F 1 412 ? 5.591   96.887  9.393   1.00 33.61  ? 412 VAL F CG2 1 
ATOM   21019 N N   . ARG F 1 413 ? 2.262   93.421  9.251   1.00 27.98  ? 413 ARG F N   1 
ATOM   21020 C CA  . ARG F 1 413 ? 1.348   92.470  8.647   1.00 29.49  ? 413 ARG F CA  1 
ATOM   21021 C C   . ARG F 1 413 ? -0.084  93.019  8.710   1.00 31.53  ? 413 ARG F C   1 
ATOM   21022 O O   . ARG F 1 413 ? -0.963  92.528  8.010   1.00 34.70  ? 413 ARG F O   1 
ATOM   21023 C CB  . ARG F 1 413 ? 1.503   91.095  9.308   1.00 29.05  ? 413 ARG F CB  1 
ATOM   21024 C CG  . ARG F 1 413 ? 2.896   90.487  9.193   1.00 29.66  ? 413 ARG F CG  1 
ATOM   21025 C CD  . ARG F 1 413 ? 3.073   89.568  8.029   1.00 32.23  ? 413 ARG F CD  1 
ATOM   21026 N NE  . ARG F 1 413 ? 2.691   90.200  6.758   1.00 36.46  ? 413 ARG F NE  1 
ATOM   21027 C CZ  . ARG F 1 413 ? 3.346   91.153  6.119   1.00 36.18  ? 413 ARG F CZ  1 
ATOM   21028 N NH1 . ARG F 1 413 ? 4.619   91.409  6.416   1.00 36.21  ? 413 ARG F NH1 1 
ATOM   21029 N NH2 . ARG F 1 413 ? 2.712   91.824  5.169   1.00 35.64  ? 413 ARG F NH2 1 
ATOM   21030 N N   . GLY F 1 414 ? -0.345  93.980  9.596   1.00 32.82  ? 414 GLY F N   1 
ATOM   21031 C CA  . GLY F 1 414 ? -1.635  94.644  9.638   1.00 33.75  ? 414 GLY F CA  1 
ATOM   21032 C C   . GLY F 1 414 ? -1.763  95.580  8.441   1.00 33.96  ? 414 GLY F C   1 
ATOM   21033 O O   . GLY F 1 414 ? -2.791  95.576  7.774   1.00 35.39  ? 414 GLY F O   1 
ATOM   21034 N N   . TYR F 1 415 ? -0.675  96.317  8.155   1.00 33.56  ? 415 TYR F N   1 
ATOM   21035 C CA  . TYR F 1 415 ? -0.595  97.261  7.043   1.00 34.05  ? 415 TYR F CA  1 
ATOM   21036 C C   . TYR F 1 415 ? -0.534  96.552  5.689   1.00 32.21  ? 415 TYR F C   1 
ATOM   21037 O O   . TYR F 1 415 ? -0.738  97.171  4.653   1.00 32.09  ? 415 TYR F O   1 
ATOM   21038 C CB  . TYR F 1 415 ? 0.713   98.063  7.022   1.00 37.69  ? 415 TYR F CB  1 
ATOM   21039 C CG  . TYR F 1 415 ? 1.077   98.939  8.209   1.00 39.50  ? 415 TYR F CG  1 
ATOM   21040 C CD1 . TYR F 1 415 ? 0.185   99.184  9.232   1.00 38.34  ? 415 TYR F CD1 1 
ATOM   21041 C CD2 . TYR F 1 415 ? 2.313   99.568  8.273   1.00 41.39  ? 415 TYR F CD2 1 
ATOM   21042 C CE1 . TYR F 1 415 ? 0.519   99.997  10.300  1.00 37.68  ? 415 TYR F CE1 1 
ATOM   21043 C CE2 . TYR F 1 415 ? 2.655   100.390 9.335   1.00 39.48  ? 415 TYR F CE2 1 
ATOM   21044 C CZ  . TYR F 1 415 ? 1.747   100.614 10.347  1.00 36.88  ? 415 TYR F CZ  1 
ATOM   21045 O OH  . TYR F 1 415 ? 2.023   101.425 11.407  1.00 36.69  ? 415 TYR F OH  1 
ATOM   21046 N N   . MET F 1 416 ? -0.090  95.295  5.694   1.00 30.80  ? 416 MET F N   1 
ATOM   21047 C CA  . MET F 1 416 ? 0.076   94.492  4.498   1.00 35.62  ? 416 MET F CA  1 
ATOM   21048 C C   . MET F 1 416 ? 1.190   95.053  3.612   1.00 38.69  ? 416 MET F C   1 
ATOM   21049 O O   . MET F 1 416 ? 0.993   95.202  2.413   1.00 43.47  ? 416 MET F O   1 
ATOM   21050 C CB  . MET F 1 416 ? -1.243  94.370  3.728   1.00 39.06  ? 416 MET F CB  1 
ATOM   21051 C CG  . MET F 1 416 ? -2.370  93.846  4.603   1.00 45.91  ? 416 MET F CG  1 
ATOM   21052 S SD  . MET F 1 416 ? -3.839  93.342  3.689   1.00 56.26  ? 416 MET F SD  1 
ATOM   21053 C CE  . MET F 1 416 ? -4.862  92.812  5.066   1.00 58.56  ? 416 MET F CE  1 
ATOM   21054 N N   . LEU F 1 417 ? 2.369   95.314  4.195   1.00 34.14  ? 417 LEU F N   1 
ATOM   21055 C CA  . LEU F 1 417 ? 3.533   95.705  3.422   1.00 30.51  ? 417 LEU F CA  1 
ATOM   21056 C C   . LEU F 1 417 ? 4.042   94.480  2.670   1.00 30.78  ? 417 LEU F C   1 
ATOM   21057 O O   . LEU F 1 417 ? 3.844   93.360  3.133   1.00 32.25  ? 417 LEU F O   1 
ATOM   21058 C CB  . LEU F 1 417 ? 4.596   96.249  4.361   1.00 30.92  ? 417 LEU F CB  1 
ATOM   21059 C CG  . LEU F 1 417 ? 4.230   97.498  5.160   1.00 32.66  ? 417 LEU F CG  1 
ATOM   21060 C CD1 . LEU F 1 417 ? 5.494   98.046  5.800   1.00 34.47  ? 417 LEU F CD1 1 
ATOM   21061 C CD2 . LEU F 1 417 ? 3.569   98.587  4.334   1.00 34.08  ? 417 LEU F CD2 1 
ATOM   21062 N N   . PRO F 1 418 ? 4.676   94.651  1.490   1.00 26.76  ? 418 PRO F N   1 
ATOM   21063 C CA  . PRO F 1 418 ? 5.127   93.533  0.657   1.00 29.16  ? 418 PRO F CA  1 
ATOM   21064 C C   . PRO F 1 418 ? 6.504   93.048  1.068   1.00 29.56  ? 418 PRO F C   1 
ATOM   21065 O O   . PRO F 1 418 ? 7.163   93.696  1.871   1.00 32.83  ? 418 PRO F O   1 
ATOM   21066 C CB  . PRO F 1 418 ? 5.216   94.133  -0.771  1.00 26.64  ? 418 PRO F CB  1 
ATOM   21067 C CG  . PRO F 1 418 ? 5.619   95.567  -0.512  1.00 28.07  ? 418 PRO F CG  1 
ATOM   21068 C CD  . PRO F 1 418 ? 4.947   95.943  0.844   1.00 29.64  ? 418 PRO F CD  1 
ATOM   21069 N N   . ILE F 1 419 ? 6.945   92.000  0.368   1.00 28.97  ? 419 ILE F N   1 
ATOM   21070 C CA  . ILE F 1 419 ? 8.277   91.436  0.483   1.00 29.57  ? 419 ILE F CA  1 
ATOM   21071 C C   . ILE F 1 419 ? 9.330   92.530  0.280   1.00 30.61  ? 419 ILE F C   1 
ATOM   21072 O O   . ILE F 1 419 ? 9.181   93.430  -0.554  1.00 33.31  ? 419 ILE F O   1 
ATOM   21073 C CB  . ILE F 1 419 ? 8.417   90.249  -0.490  1.00 31.54  ? 419 ILE F CB  1 
ATOM   21074 C CG1 . ILE F 1 419 ? 9.681   89.430  -0.252  1.00 32.39  ? 419 ILE F CG1 1 
ATOM   21075 C CG2 . ILE F 1 419 ? 8.323   90.689  -1.955  1.00 32.71  ? 419 ILE F CG2 1 
ATOM   21076 C CD1 . ILE F 1 419 ? 9.669   88.063  -0.933  1.00 32.68  ? 419 ILE F CD1 1 
ATOM   21077 N N   . GLU F 1 420 ? 10.392  92.470  1.083   1.00 28.84  ? 420 GLU F N   1 
ATOM   21078 C CA  . GLU F 1 420 ? 11.505  93.387  0.926   1.00 30.34  ? 420 GLU F CA  1 
ATOM   21079 C C   . GLU F 1 420 ? 12.445  92.785  -0.098  1.00 30.28  ? 420 GLU F C   1 
ATOM   21080 O O   . GLU F 1 420 ? 12.822  91.623  0.059   1.00 29.37  ? 420 GLU F O   1 
ATOM   21081 C CB  . GLU F 1 420 ? 12.163  93.606  2.284   1.00 33.18  ? 420 GLU F CB  1 
ATOM   21082 C CG  . GLU F 1 420 ? 13.490  94.368  2.259   1.00 34.39  ? 420 GLU F CG  1 
ATOM   21083 C CD  . GLU F 1 420 ? 14.006  94.698  3.667   1.00 34.05  ? 420 GLU F CD  1 
ATOM   21084 O OE1 . GLU F 1 420 ? 15.219  95.005  3.825   1.00 30.07  ? 420 GLU F OE1 1 
ATOM   21085 O OE2 . GLU F 1 420 ? 13.166  94.644  4.605   1.00 29.71  ? 420 GLU F OE2 1 
ATOM   21086 N N   . ARG F 1 421 ? 12.787  93.581  -1.126  1.00 31.02  ? 421 ARG F N   1 
ATOM   21087 C CA  . ARG F 1 421 ? 13.625  93.140  -2.230  1.00 33.24  ? 421 ARG F CA  1 
ATOM   21088 C C   . ARG F 1 421 ? 14.221  94.359  -2.933  1.00 34.49  ? 421 ARG F C   1 
ATOM   21089 O O   . ARG F 1 421 ? 13.744  94.787  -4.006  1.00 29.68  ? 421 ARG F O   1 
ATOM   21090 C CB  . ARG F 1 421 ? 12.896  92.269  -3.266  1.00 37.88  ? 421 ARG F CB  1 
ATOM   21091 C CG  . ARG F 1 421 ? 13.841  91.396  -4.084  1.00 42.17  ? 421 ARG F CG  1 
ATOM   21092 C CD  . ARG F 1 421 ? 13.323  90.947  -5.436  1.00 48.58  ? 421 ARG F CD  1 
ATOM   21093 N NE  . ARG F 1 421 ? 14.297  90.167  -6.209  1.00 59.95  ? 421 ARG F NE  1 
ATOM   21094 C CZ  . ARG F 1 421 ? 15.533  90.552  -6.565  1.00 76.63  ? 421 ARG F CZ  1 
ATOM   21095 N NH1 . ARG F 1 421 ? 15.975  91.764  -6.262  1.00 76.96  ? 421 ARG F NH1 1 
ATOM   21096 N NH2 . ARG F 1 421 ? 16.334  89.713  -7.215  1.00 78.72  ? 421 ARG F NH2 1 
ATOM   21097 N N   . PRO F 1 422 ? 15.323  94.912  -2.364  1.00 32.35  ? 422 PRO F N   1 
ATOM   21098 C CA  . PRO F 1 422 ? 16.068  95.994  -2.993  1.00 29.78  ? 422 PRO F CA  1 
ATOM   21099 C C   . PRO F 1 422 ? 16.768  95.423  -4.206  1.00 33.53  ? 422 PRO F C   1 
ATOM   21100 O O   . PRO F 1 422 ? 16.782  94.203  -4.387  1.00 33.82  ? 422 PRO F O   1 
ATOM   21101 C CB  . PRO F 1 422 ? 17.072  96.446  -1.950  1.00 30.02  ? 422 PRO F CB  1 
ATOM   21102 C CG  . PRO F 1 422 ? 17.255  95.240  -1.059  1.00 30.37  ? 422 PRO F CG  1 
ATOM   21103 C CD  . PRO F 1 422 ? 15.951  94.475  -1.108  1.00 32.35  ? 422 PRO F CD  1 
ATOM   21104 N N   . LYS F 1 423 ? 17.360  96.337  -4.986  1.00 36.33  ? 423 LYS F N   1 
ATOM   21105 C CA  . LYS F 1 423 ? 18.191  96.014  -6.139  1.00 38.72  ? 423 LYS F CA  1 
ATOM   21106 C C   . LYS F 1 423 ? 19.676  96.017  -5.749  1.00 36.13  ? 423 LYS F C   1 
ATOM   21107 O O   . LYS F 1 423 ? 20.160  96.957  -5.137  1.00 36.15  ? 423 LYS F O   1 
ATOM   21108 C CB  . LYS F 1 423 ? 17.852  97.049  -7.223  1.00 41.05  ? 423 LYS F CB  1 
ATOM   21109 C CG  . LYS F 1 423 ? 18.694  97.035  -8.506  1.00 43.75  ? 423 LYS F CG  1 
ATOM   21110 C CD  . LYS F 1 423 ? 18.628  95.768  -9.355  1.00 45.00  ? 423 LYS F CD  1 
ATOM   21111 C CE  . LYS F 1 423 ? 19.543  95.865  -10.545 1.00 44.97  ? 423 LYS F CE  1 
ATOM   21112 N NZ  . LYS F 1 423 ? 19.559  94.586  -11.243 1.00 42.97  ? 423 LYS F NZ  1 
ATOM   21113 N N   . SER F 1 424 ? 20.416  94.970  -6.130  1.00 34.92  ? 424 SER F N   1 
ATOM   21114 C CA  . SER F 1 424 ? 21.857  94.982  -5.972  1.00 32.13  ? 424 SER F CA  1 
ATOM   21115 C C   . SER F 1 424 ? 22.500  95.504  -7.260  1.00 31.07  ? 424 SER F C   1 
ATOM   21116 O O   . SER F 1 424 ? 21.914  95.421  -8.346  1.00 31.16  ? 424 SER F O   1 
ATOM   21117 C CB  . SER F 1 424 ? 22.378  93.615  -5.560  1.00 31.14  ? 424 SER F CB  1 
ATOM   21118 O OG  . SER F 1 424 ? 22.152  92.642  -6.569  1.00 31.67  ? 424 SER F OG  1 
ATOM   21119 N N   . ILE F 1 425 ? 23.705  96.071  -7.112  1.00 30.03  ? 425 ILE F N   1 
ATOM   21120 C CA  . ILE F 1 425 ? 24.512  96.528  -8.239  1.00 31.83  ? 425 ILE F CA  1 
ATOM   21121 C C   . ILE F 1 425 ? 25.878  95.856  -8.152  1.00 32.94  ? 425 ILE F C   1 
ATOM   21122 O O   . ILE F 1 425 ? 26.252  95.400  -7.062  1.00 36.77  ? 425 ILE F O   1 
ATOM   21123 C CB  . ILE F 1 425 ? 24.622  98.059  -8.239  1.00 30.25  ? 425 ILE F CB  1 
ATOM   21124 C CG1 . ILE F 1 425 ? 25.369  98.549  -7.018  1.00 31.87  ? 425 ILE F CG1 1 
ATOM   21125 C CG2 . ILE F 1 425 ? 23.236  98.700  -8.320  1.00 31.80  ? 425 ILE F CG2 1 
ATOM   21126 C CD1 . ILE F 1 425 ? 25.535  100.058 -6.958  1.00 33.40  ? 425 ILE F CD1 1 
ATOM   21127 N N   . THR F 1 426 ? 26.586  95.779  -9.296  1.00 30.57  ? 426 THR F N   1 
ATOM   21128 C CA  . THR F 1 426 ? 27.926  95.198  -9.368  1.00 32.05  ? 426 THR F CA  1 
ATOM   21129 C C   . THR F 1 426 ? 28.938  96.336  -9.389  1.00 33.33  ? 426 THR F C   1 
ATOM   21130 O O   . THR F 1 426 ? 28.595  97.455  -9.761  1.00 35.17  ? 426 THR F O   1 
ATOM   21131 C CB  . THR F 1 426 ? 28.137  94.309  -10.600 1.00 30.83  ? 426 THR F CB  1 
ATOM   21132 O OG1 . THR F 1 426 ? 28.125  95.144  -11.755 1.00 33.57  ? 426 THR F OG1 1 
ATOM   21133 C CG2 . THR F 1 426 ? 27.048  93.267  -10.763 1.00 32.56  ? 426 THR F CG2 1 
ATOM   21134 N N   . THR F 1 427 ? 30.178  95.995  -9.044  1.00 32.88  ? 427 THR F N   1 
ATOM   21135 C CA  . THR F 1 427 ? 31.304  96.910  -9.024  1.00 35.87  ? 427 THR F CA  1 
ATOM   21136 C C   . THR F 1 427 ? 31.709  97.214  -10.463 1.00 38.58  ? 427 THR F C   1 
ATOM   21137 O O   . THR F 1 427 ? 32.047  98.355  -10.761 1.00 34.13  ? 427 THR F O   1 
ATOM   21138 C CB  . THR F 1 427 ? 32.433  96.284  -8.192  1.00 36.84  ? 427 THR F CB  1 
ATOM   21139 O OG1 . THR F 1 427 ? 31.949  96.172  -6.856  1.00 37.22  ? 427 THR F OG1 1 
ATOM   21140 C CG2 . THR F 1 427 ? 33.660  97.163  -8.045  1.00 38.10  ? 427 THR F CG2 1 
ATOM   21141 N N   . ARG F 1 428 ? 31.639  96.198  -11.345 1.00 45.46  ? 428 ARG F N   1 
ATOM   21142 C CA  . ARG F 1 428 ? 31.864  96.374  -12.778 1.00 47.64  ? 428 ARG F CA  1 
ATOM   21143 C C   . ARG F 1 428 ? 30.944  97.465  -13.332 1.00 44.75  ? 428 ARG F C   1 
ATOM   21144 O O   . ARG F 1 428 ? 31.408  98.346  -14.043 1.00 49.04  ? 428 ARG F O   1 
ATOM   21145 C CB  . ARG F 1 428 ? 31.731  95.062  -13.565 1.00 53.69  ? 428 ARG F CB  1 
ATOM   21146 C CG  . ARG F 1 428 ? 31.460  95.159  -15.065 1.00 66.51  ? 428 ARG F CG  1 
ATOM   21147 C CD  . ARG F 1 428 ? 29.945  95.303  -15.354 1.00 81.80  ? 428 ARG F CD  1 
ATOM   21148 N NE  . ARG F 1 428 ? 29.558  95.404  -16.767 1.00 91.62  ? 428 ARG F NE  1 
ATOM   21149 C CZ  . ARG F 1 428 ? 29.686  94.424  -17.671 1.00 103.64 ? 428 ARG F CZ  1 
ATOM   21150 N NH1 . ARG F 1 428 ? 30.205  93.262  -17.306 1.00 111.05 ? 428 ARG F NH1 1 
ATOM   21151 N NH2 . ARG F 1 428 ? 29.308  94.599  -18.935 1.00 89.63  ? 428 ARG F NH2 1 
ATOM   21152 N N   . TRP F 1 429 ? 29.643  97.400  -13.035 1.00 37.98  ? 429 TRP F N   1 
ATOM   21153 C CA  . TRP F 1 429 ? 28.726  98.434  -13.473 1.00 40.33  ? 429 TRP F CA  1 
ATOM   21154 C C   . TRP F 1 429 ? 29.155  99.809  -12.954 1.00 45.82  ? 429 TRP F C   1 
ATOM   21155 O O   . TRP F 1 429 ? 29.057  100.815 -13.664 1.00 47.62  ? 429 TRP F O   1 
ATOM   21156 C CB  . TRP F 1 429 ? 27.306  98.105  -13.005 1.00 39.72  ? 429 TRP F CB  1 
ATOM   21157 C CG  . TRP F 1 429 ? 26.247  99.096  -13.411 1.00 37.61  ? 429 TRP F CG  1 
ATOM   21158 C CD1 . TRP F 1 429 ? 25.614  99.169  -14.616 1.00 42.00  ? 429 TRP F CD1 1 
ATOM   21159 C CD2 . TRP F 1 429 ? 25.621  100.095 -12.582 1.00 39.60  ? 429 TRP F CD2 1 
ATOM   21160 N NE1 . TRP F 1 429 ? 24.650  100.142 -14.603 1.00 39.47  ? 429 TRP F NE1 1 
ATOM   21161 C CE2 . TRP F 1 429 ? 24.636  100.732 -13.371 1.00 40.53  ? 429 TRP F CE2 1 
ATOM   21162 C CE3 . TRP F 1 429 ? 25.803  100.522 -11.261 1.00 39.40  ? 429 TRP F CE3 1 
ATOM   21163 C CZ2 . TRP F 1 429 ? 23.839  101.762 -12.880 1.00 41.36  ? 429 TRP F CZ2 1 
ATOM   21164 C CZ3 . TRP F 1 429 ? 25.018  101.545 -10.777 1.00 38.49  ? 429 TRP F CZ3 1 
ATOM   21165 C CH2 . TRP F 1 429 ? 24.041  102.147 -11.574 1.00 42.21  ? 429 TRP F CH2 1 
ATOM   21166 N N   . VAL F 1 430 ? 29.604  99.849  -11.696 1.00 44.27  ? 430 VAL F N   1 
ATOM   21167 C CA  . VAL F 1 430 ? 29.881  101.113 -11.038 1.00 43.77  ? 430 VAL F CA  1 
ATOM   21168 C C   . VAL F 1 430 ? 31.068  101.786 -11.727 1.00 43.05  ? 430 VAL F C   1 
ATOM   21169 O O   . VAL F 1 430 ? 30.992  102.982 -12.005 1.00 38.80  ? 430 VAL F O   1 
ATOM   21170 C CB  . VAL F 1 430 ? 30.077  100.961 -9.515  1.00 38.90  ? 430 VAL F CB  1 
ATOM   21171 C CG1 . VAL F 1 430 ? 30.608  102.243 -8.884  1.00 39.00  ? 430 VAL F CG1 1 
ATOM   21172 C CG2 . VAL F 1 430 ? 28.772  100.554 -8.841  1.00 38.33  ? 430 VAL F CG2 1 
ATOM   21173 N N   . LYS F 1 431 ? 32.124  101.007 -12.025 1.00 44.74  ? 431 LYS F N   1 
ATOM   21174 C CA  . LYS F 1 431 ? 33.298  101.488 -12.744 1.00 49.10  ? 431 LYS F CA  1 
ATOM   21175 C C   . LYS F 1 431 ? 32.892  102.131 -14.085 1.00 57.27  ? 431 LYS F C   1 
ATOM   21176 O O   . LYS F 1 431 ? 33.238  103.276 -14.395 1.00 58.66  ? 431 LYS F O   1 
ATOM   21177 C CB  . LYS F 1 431 ? 34.267  100.320 -12.954 1.00 51.08  ? 431 LYS F CB  1 
ATOM   21178 C CG  . LYS F 1 431 ? 34.743  99.573  -11.715 1.00 59.68  ? 431 LYS F CG  1 
ATOM   21179 C CD  . LYS F 1 431 ? 36.034  100.086 -11.111 1.00 71.46  ? 431 LYS F CD  1 
ATOM   21180 C CE  . LYS F 1 431 ? 37.216  99.635  -11.887 1.00 87.11  ? 431 LYS F CE  1 
ATOM   21181 N NZ  . LYS F 1 431 ? 38.254  100.667 -11.805 1.00 100.49 ? 431 LYS F NZ  1 
ATOM   21182 N N   . GLU F 1 432 ? 32.121  101.399 -14.891 1.00 60.90  ? 432 GLU F N   1 
ATOM   21183 C CA  . GLU F 1 432 ? 31.772  101.825 -16.241 1.00 64.45  ? 432 GLU F CA  1 
ATOM   21184 C C   . GLU F 1 432 ? 30.981  103.135 -16.199 1.00 65.94  ? 432 GLU F C   1 
ATOM   21185 O O   . GLU F 1 432 ? 31.228  104.031 -17.004 1.00 62.45  ? 432 GLU F O   1 
ATOM   21186 C CB  . GLU F 1 432 ? 31.065  100.601 -16.822 1.00 67.67  ? 432 GLU F CB  1 
ATOM   21187 C CG  . GLU F 1 432 ? 30.424  100.728 -18.200 1.00 74.65  ? 432 GLU F CG  1 
ATOM   21188 C CD  . GLU F 1 432 ? 29.531  99.512  -18.460 1.00 82.70  ? 432 GLU F CD  1 
ATOM   21189 O OE1 . GLU F 1 432 ? 29.994  98.376  -18.142 1.00 74.11  ? 432 GLU F OE1 1 
ATOM   21190 O OE2 . GLU F 1 432 ? 28.374  99.676  -18.939 1.00 78.70  ? 432 GLU F OE2 1 
ATOM   21191 N N   . VAL F 1 433 ? 30.089  103.268 -15.205 1.00 63.58  ? 433 VAL F N   1 
ATOM   21192 C CA  . VAL F 1 433 ? 29.002  104.234 -15.248 1.00 57.24  ? 433 VAL F CA  1 
ATOM   21193 C C   . VAL F 1 433 ? 29.295  105.479 -14.404 1.00 52.20  ? 433 VAL F C   1 
ATOM   21194 O O   . VAL F 1 433 ? 28.708  106.529 -14.638 1.00 52.01  ? 433 VAL F O   1 
ATOM   21195 C CB  . VAL F 1 433 ? 27.732  103.486 -14.798 1.00 62.12  ? 433 VAL F CB  1 
ATOM   21196 C CG1 . VAL F 1 433 ? 26.634  104.403 -14.294 1.00 66.40  ? 433 VAL F CG1 1 
ATOM   21197 C CG2 . VAL F 1 433 ? 27.197  102.588 -15.905 1.00 65.51  ? 433 VAL F CG2 1 
ATOM   21198 N N   . ALA F 1 434 ? 30.212  105.394 -13.440 1.00 52.70  ? 434 ALA F N   1 
ATOM   21199 C CA  . ALA F 1 434 ? 30.261  106.379 -12.363 1.00 54.02  ? 434 ALA F CA  1 
ATOM   21200 C C   . ALA F 1 434 ? 30.543  107.786 -12.882 1.00 52.67  ? 434 ALA F C   1 
ATOM   21201 O O   . ALA F 1 434 ? 29.953  108.746 -12.389 1.00 53.24  ? 434 ALA F O   1 
ATOM   21202 C CB  . ALA F 1 434 ? 31.282  105.986 -11.317 1.00 51.71  ? 434 ALA F CB  1 
ATOM   21203 N N   . GLU F 1 435 ? 31.460  107.913 -13.848 1.00 58.12  ? 435 GLU F N   1 
ATOM   21204 C CA  . GLU F 1 435 ? 31.879  109.232 -14.301 1.00 60.49  ? 435 GLU F CA  1 
ATOM   21205 C C   . GLU F 1 435 ? 30.660  109.982 -14.835 1.00 54.87  ? 435 GLU F C   1 
ATOM   21206 O O   . GLU F 1 435 ? 30.568  111.191 -14.650 1.00 47.07  ? 435 GLU F O   1 
ATOM   21207 C CB  . GLU F 1 435 ? 33.044  109.219 -15.300 1.00 61.56  ? 435 GLU F CB  1 
ATOM   21208 C CG  . GLU F 1 435 ? 34.434  109.221 -14.653 1.00 62.49  ? 435 GLU F CG  1 
ATOM   21209 C CD  . GLU F 1 435 ? 34.847  110.473 -13.871 1.00 59.17  ? 435 GLU F CD  1 
ATOM   21210 O OE1 . GLU F 1 435 ? 34.541  111.586 -14.342 1.00 51.03  ? 435 GLU F OE1 1 
ATOM   21211 O OE2 . GLU F 1 435 ? 35.499  110.369 -12.802 1.00 59.51  ? 435 GLU F OE2 1 
ATOM   21212 N N   . SER F 1 436 ? 29.706  109.245 -15.424 1.00 52.02  ? 436 SER F N   1 
ATOM   21213 C CA  . SER F 1 436 ? 28.552  109.837 -16.081 1.00 48.85  ? 436 SER F CA  1 
ATOM   21214 C C   . SER F 1 436 ? 27.455  110.248 -15.099 1.00 47.03  ? 436 SER F C   1 
ATOM   21215 O O   . SER F 1 436 ? 26.498  110.901 -15.488 1.00 48.09  ? 436 SER F O   1 
ATOM   21216 C CB  . SER F 1 436 ? 27.989  108.881 -17.106 1.00 52.52  ? 436 SER F CB  1 
ATOM   21217 O OG  . SER F 1 436 ? 26.963  108.065 -16.552 1.00 55.72  ? 436 SER F OG  1 
ATOM   21218 N N   . LEU F 1 437 ? 27.534  109.826 -13.835 1.00 49.82  ? 437 LEU F N   1 
ATOM   21219 C CA  . LEU F 1 437 ? 26.422  110.031 -12.919 1.00 46.07  ? 437 LEU F CA  1 
ATOM   21220 C C   . LEU F 1 437 ? 26.521  111.424 -12.305 1.00 46.61  ? 437 LEU F C   1 
ATOM   21221 O O   . LEU F 1 437 ? 27.623  111.915 -12.055 1.00 48.49  ? 437 LEU F O   1 
ATOM   21222 C CB  . LEU F 1 437 ? 26.448  108.960 -11.828 1.00 50.89  ? 437 LEU F CB  1 
ATOM   21223 C CG  . LEU F 1 437 ? 26.050  107.530 -12.223 1.00 48.22  ? 437 LEU F CG  1 
ATOM   21224 C CD1 . LEU F 1 437 ? 26.199  106.631 -10.994 1.00 45.69  ? 437 LEU F CD1 1 
ATOM   21225 C CD2 . LEU F 1 437 ? 24.636  107.427 -12.801 1.00 45.22  ? 437 LEU F CD2 1 
ATOM   21226 N N   . PRO F 1 438 ? 25.385  112.100 -12.026 1.00 42.26  ? 438 PRO F N   1 
ATOM   21227 C CA  . PRO F 1 438 ? 25.410  113.365 -11.285 1.00 42.80  ? 438 PRO F CA  1 
ATOM   21228 C C   . PRO F 1 438 ? 25.884  113.250 -9.835  1.00 43.29  ? 438 PRO F C   1 
ATOM   21229 O O   . PRO F 1 438 ? 25.665  112.241 -9.179  1.00 46.52  ? 438 PRO F O   1 
ATOM   21230 C CB  . PRO F 1 438 ? 23.939  113.838 -11.357 1.00 45.21  ? 438 PRO F CB  1 
ATOM   21231 C CG  . PRO F 1 438 ? 23.135  112.579 -11.589 1.00 41.74  ? 438 PRO F CG  1 
ATOM   21232 C CD  . PRO F 1 438 ? 24.030  111.680 -12.417 1.00 39.75  ? 438 PRO F CD  1 
ATOM   21233 N N   . VAL F 1 439 ? 26.552  114.298 -9.347  1.00 46.36  ? 439 VAL F N   1 
ATOM   21234 C CA  . VAL F 1 439 ? 26.844  114.469 -7.934  1.00 47.90  ? 439 VAL F CA  1 
ATOM   21235 C C   . VAL F 1 439 ? 25.546  114.837 -7.219  1.00 51.73  ? 439 VAL F C   1 
ATOM   21236 O O   . VAL F 1 439 ? 24.758  115.619 -7.740  1.00 49.90  ? 439 VAL F O   1 
ATOM   21237 C CB  . VAL F 1 439 ? 27.927  115.559 -7.777  1.00 51.45  ? 439 VAL F CB  1 
ATOM   21238 C CG1 . VAL F 1 439 ? 28.053  116.086 -6.340  1.00 50.47  ? 439 VAL F CG1 1 
ATOM   21239 C CG2 . VAL F 1 439 ? 29.279  115.088 -8.324  1.00 46.67  ? 439 VAL F CG2 1 
ATOM   21240 N N   . ALA F 1 440 ? 25.308  114.259 -6.034  1.00 56.41  ? 440 ALA F N   1 
ATOM   21241 C CA  . ALA F 1 440 ? 24.107  114.559 -5.271  1.00 57.67  ? 440 ALA F CA  1 
ATOM   21242 C C   . ALA F 1 440 ? 24.356  115.774 -4.375  1.00 65.66  ? 440 ALA F C   1 
ATOM   21243 O O   . ALA F 1 440 ? 25.466  115.943 -3.859  1.00 59.12  ? 440 ALA F O   1 
ATOM   21244 C CB  . ALA F 1 440 ? 23.694  113.338 -4.483  1.00 56.08  ? 440 ALA F CB  1 
ATOM   21245 N N   . GLY F 1 441 ? 23.322  116.620 -4.212  1.00 73.51  ? 441 GLY F N   1 
ATOM   21246 C CA  . GLY F 1 441 ? 23.391  117.759 -3.303  1.00 82.55  ? 441 GLY F CA  1 
ATOM   21247 C C   . GLY F 1 441 ? 22.069  117.892 -2.535  1.00 76.70  ? 441 GLY F C   1 
ATOM   21248 O O   . GLY F 1 441 ? 22.147  118.416 -1.403  1.00 80.91  ? 441 GLY F O   1 
HETATM 21249 O O1  . OAA G 2 .   ? 1.888   23.250  19.286  1.00 44.14  ? 501 OAA A O1  1 
HETATM 21250 O O2  . OAA G 2 .   ? 0.379   23.977  20.718  1.00 51.75  ? 501 OAA A O2  1 
HETATM 21251 O O4  . OAA G 2 .   ? 5.507   24.747  18.939  1.00 72.52  ? 501 OAA A O4  1 
HETATM 21252 O O5  . OAA G 2 .   ? 4.135   26.311  19.478  1.00 56.07  ? 501 OAA A O5  1 
HETATM 21253 O O3  . OAA G 2 .   ? 4.486   23.277  20.707  1.00 81.27  ? 501 OAA A O3  1 
HETATM 21254 C C1  . OAA G 2 .   ? 1.555   23.882  20.300  1.00 52.21  ? 501 OAA A C1  1 
HETATM 21255 C C2  . OAA G 2 .   ? 2.644   24.607  21.079  1.00 59.08  ? 501 OAA A C2  1 
HETATM 21256 C C3  . OAA G 2 .   ? 3.962   24.348  20.454  1.00 66.49  ? 501 OAA A C3  1 
HETATM 21257 C C4  . OAA G 2 .   ? 4.541   25.160  19.595  1.00 68.08  ? 501 OAA A C4  1 
HETATM 21258 N N1A . ACO H 3 .   ? -3.477  14.507  35.713  1.00 85.95  ? 502 ACO A N1A 1 
HETATM 21259 C C2A . ACO H 3 .   ? -3.150  13.512  34.873  1.00 92.27  ? 502 ACO A C2A 1 
HETATM 21260 N N3A . ACO H 3 .   ? -2.523  13.576  33.699  1.00 101.97 ? 502 ACO A N3A 1 
HETATM 21261 C C4A . ACO H 3 .   ? -2.213  14.851  33.391  1.00 113.82 ? 502 ACO A C4A 1 
HETATM 21262 C C5A . ACO H 3 .   ? -2.479  15.978  34.150  1.00 113.23 ? 502 ACO A C5A 1 
HETATM 21263 C C6A . ACO H 3 .   ? -3.149  15.780  35.380  1.00 84.67  ? 502 ACO A C6A 1 
HETATM 21264 N N6A . ACO H 3 .   ? -3.468  16.757  36.223  1.00 72.52  ? 502 ACO A N6A 1 
HETATM 21265 N N7A . ACO H 3 .   ? -1.999  17.119  33.505  1.00 115.41 ? 502 ACO A N7A 1 
HETATM 21266 C C8A . ACO H 3 .   ? -1.462  16.671  32.391  1.00 118.91 ? 502 ACO A C8A 1 
HETATM 21267 N N9A . ACO H 3 .   ? -1.566  15.290  32.265  1.00 113.39 ? 502 ACO A N9A 1 
HETATM 21268 C C1B . ACO H 3 .   ? -1.101  14.440  31.158  1.00 104.84 ? 502 ACO A C1B 1 
HETATM 21269 C C2B . ACO H 3 .   ? -2.134  13.414  30.693  1.00 104.33 ? 502 ACO A C2B 1 
HETATM 21270 O O2B . ACO H 3 .   ? -1.836  12.169  31.295  1.00 103.46 ? 502 ACO A O2B 1 
HETATM 21271 C C3B . ACO H 3 .   ? -2.025  13.444  29.155  1.00 98.14  ? 502 ACO A C3B 1 
HETATM 21272 O O3B . ACO H 3 .   ? -1.036  12.614  28.535  1.00 107.46 ? 502 ACO A O3B 1 
HETATM 21273 P P3B . ACO H 3 .   ? -1.547  11.474  27.478  1.00 119.24 ? 502 ACO A P3B 1 
HETATM 21274 O O7A . ACO H 3 .   ? -2.991  11.808  27.077  1.00 98.98  ? 502 ACO A O7A 1 
HETATM 21275 O O8A . ACO H 3 .   ? -1.453  10.213  28.351  1.00 97.03  ? 502 ACO A O8A 1 
HETATM 21276 O O9A . ACO H 3 .   ? -0.636  11.382  26.245  1.00 72.11  ? 502 ACO A O9A 1 
HETATM 21277 C C4B . ACO H 3 .   ? -1.575  14.859  28.885  1.00 91.29  ? 502 ACO A C4B 1 
HETATM 21278 O O4B . ACO H 3 .   ? -0.817  15.266  30.054  1.00 102.40 ? 502 ACO A O4B 1 
HETATM 21279 C C5B . ACO H 3 .   ? -2.675  15.852  28.655  1.00 87.16  ? 502 ACO A C5B 1 
HETATM 21280 O O5B . ACO H 3 .   ? -2.090  17.140  28.902  1.00 85.71  ? 502 ACO A O5B 1 
HETATM 21281 P P1A . ACO H 3 .   ? -3.043  18.381  29.168  1.00 84.46  ? 502 ACO A P1A 1 
HETATM 21282 O O1A . ACO H 3 .   ? -2.556  19.104  30.390  1.00 81.94  ? 502 ACO A O1A 1 
HETATM 21283 O O2A . ACO H 3 .   ? -4.458  17.890  29.157  1.00 85.20  ? 502 ACO A O2A 1 
HETATM 21284 O O3A . ACO H 3 .   ? -2.728  19.230  27.823  1.00 89.79  ? 502 ACO A O3A 1 
HETATM 21285 P P2A . ACO H 3 .   ? -3.038  20.728  27.278  1.00 87.30  ? 502 ACO A P2A 1 
HETATM 21286 O O4A . ACO H 3 .   ? -1.807  21.593  27.350  1.00 67.48  ? 502 ACO A O4A 1 
HETATM 21287 O O5A . ACO H 3 .   ? -3.656  20.577  25.919  1.00 91.43  ? 502 ACO A O5A 1 
HETATM 21288 O O6A . ACO H 3 .   ? -4.082  21.194  28.441  1.00 86.06  ? 502 ACO A O6A 1 
HETATM 21289 C CBP . ACO H 3 .   ? -6.551  20.925  28.795  1.00 96.64  ? 502 ACO A CBP 1 
HETATM 21290 C CCP . ACO H 3 .   ? -5.418  21.741  28.154  1.00 88.43  ? 502 ACO A CCP 1 
HETATM 21291 C CDP . ACO H 3 .   ? -7.885  21.691  28.704  1.00 92.17  ? 502 ACO A CDP 1 
HETATM 21292 C CEP . ACO H 3 .   ? -6.704  19.588  28.046  1.00 96.63  ? 502 ACO A CEP 1 
HETATM 21293 C CAP . ACO H 3 .   ? -6.162  20.685  30.263  1.00 104.05 ? 502 ACO A CAP 1 
HETATM 21294 O OAP . ACO H 3 .   ? -5.395  21.828  30.655  1.00 115.00 ? 502 ACO A OAP 1 
HETATM 21295 C C9P . ACO H 3 .   ? -7.201  20.433  31.350  1.00 98.33  ? 502 ACO A C9P 1 
HETATM 21296 O O9P . ACO H 3 .   ? -7.808  19.363  31.429  1.00 90.90  ? 502 ACO A O9P 1 
HETATM 21297 N N8P . ACO H 3 .   ? -7.372  21.421  32.216  1.00 86.85  ? 502 ACO A N8P 1 
HETATM 21298 C C7P . ACO H 3 .   ? -7.239  21.161  33.634  1.00 87.03  ? 502 ACO A C7P 1 
HETATM 21299 C C6P . ACO H 3 .   ? -5.783  20.827  33.900  1.00 90.83  ? 502 ACO A C6P 1 
HETATM 21300 C C5P . ACO H 3 .   ? -5.428  20.350  35.286  1.00 87.40  ? 502 ACO A C5P 1 
HETATM 21301 O O5P . ACO H 3 .   ? -5.194  19.166  35.505  1.00 63.23  ? 502 ACO A O5P 1 
HETATM 21302 N N4P . ACO H 3 .   ? -5.337  21.284  36.235  1.00 107.86 ? 502 ACO A N4P 1 
HETATM 21303 C C3P . ACO H 3 .   ? -5.526  22.713  36.005  1.00 122.72 ? 502 ACO A C3P 1 
HETATM 21304 C C2P . ACO H 3 .   ? -6.986  23.162  36.022  1.00 126.58 ? 502 ACO A C2P 1 
HETATM 21305 S S1P . ACO H 3 .   ? -8.042  22.828  37.487  1.00 142.02 ? 502 ACO A S1P 1 
HETATM 21306 C C   . ACO H 3 .   ? -8.073  21.475  38.670  1.00 117.50 ? 502 ACO A C   1 
HETATM 21307 O O   . ACO H 3 .   ? -7.268  20.574  38.668  1.00 107.41 ? 502 ACO A O   1 
HETATM 21308 C CH3 . ACO H 3 .   ? -9.210  21.534  39.639  1.00 105.05 ? 502 ACO A CH3 1 
HETATM 21309 O O1  . OAA I 2 .   ? -18.512 42.450  19.167  1.00 67.58  ? 501 OAA B O1  1 
HETATM 21310 O O2  . OAA I 2 .   ? -18.445 43.118  21.238  1.00 68.26  ? 501 OAA B O2  1 
HETATM 21311 O O4  . OAA I 2 .   ? -19.358 46.504  20.359  1.00 82.15  ? 501 OAA B O4  1 
HETATM 21312 O O5  . OAA I 2 .   ? -18.022 47.382  21.831  1.00 71.52  ? 501 OAA B O5  1 
HETATM 21313 O O3  . OAA I 2 .   ? -16.362 45.624  21.429  1.00 56.29  ? 501 OAA B O3  1 
HETATM 21314 C C1  . OAA I 2 .   ? -18.196 43.277  20.046  1.00 69.51  ? 501 OAA B C1  1 
HETATM 21315 C C2  . OAA I 2 .   ? -17.443 44.544  19.639  1.00 67.81  ? 501 OAA B C2  1 
HETATM 21316 C C3  . OAA I 2 .   ? -17.362 45.595  20.735  1.00 68.32  ? 501 OAA B C3  1 
HETATM 21317 C C4  . OAA I 2 .   ? -18.279 46.514  20.983  1.00 79.27  ? 501 OAA B C4  1 
HETATM 21318 O O1  . OAA J 2 .   ? 15.147  86.609  -7.257  1.00 27.13  ? 501 OAA D O1  1 
HETATM 21319 O O2  . OAA J 2 .   ? 14.030  87.598  -5.862  1.00 28.38  ? 501 OAA D O2  1 
HETATM 21320 O O4  . OAA J 2 .   ? 15.985  82.987  -6.755  1.00 63.78  ? 501 OAA D O4  1 
HETATM 21321 O O5  . OAA J 2 .   ? 15.609  84.273  -5.058  1.00 51.01  ? 501 OAA D O5  1 
HETATM 21322 O O3  . OAA J 2 .   ? 13.859  83.801  -7.944  1.00 58.76  ? 501 OAA D O3  1 
HETATM 21323 C C1  . OAA J 2 .   ? 14.260  86.656  -6.517  1.00 27.74  ? 501 OAA D C1  1 
HETATM 21324 C C2  . OAA J 2 .   ? 13.380  85.445  -6.399  1.00 37.35  ? 501 OAA D C2  1 
HETATM 21325 C C3  . OAA J 2 .   ? 14.190  84.296  -6.873  1.00 52.34  ? 501 OAA D C3  1 
HETATM 21326 C C4  . OAA J 2 .   ? 15.283  83.838  -6.191  1.00 65.07  ? 501 OAA D C4  1 
HETATM 21327 N N1A . COA K 4 .   ? -0.694  85.154  -11.383 1.00 36.66  ? 502 COA D N1A 1 
HETATM 21328 C C2A . COA K 4 .   ? -1.593  86.105  -11.091 1.00 38.76  ? 502 COA D C2A 1 
HETATM 21329 N N3A . COA K 4 .   ? -1.414  87.414  -10.913 1.00 38.91  ? 502 COA D N3A 1 
HETATM 21330 C C4A . COA K 4 .   ? -0.123  87.740  -11.055 1.00 39.35  ? 502 COA D C4A 1 
HETATM 21331 C C5A . COA K 4 .   ? 0.913   86.884  -11.368 1.00 36.78  ? 502 COA D C5A 1 
HETATM 21332 C C6A . COA K 4 .   ? 0.605   85.520  -11.530 1.00 35.76  ? 502 COA D C6A 1 
HETATM 21333 N N6A . COA K 4 .   ? 1.513   84.589  -11.808 1.00 32.71  ? 502 COA D N6A 1 
HETATM 21334 N N7A . COA K 4 .   ? 2.104   87.586  -11.441 1.00 38.36  ? 502 COA D N7A 1 
HETATM 21335 C C8A . COA K 4 .   ? 1.774   88.829  -11.173 1.00 40.26  ? 502 COA D C8A 1 
HETATM 21336 N N9A . COA K 4 .   ? 0.424   88.991  -10.959 1.00 43.40  ? 502 COA D N9A 1 
HETATM 21337 C C1B . COA K 4 .   ? -0.288  90.227  -10.538 1.00 49.83  ? 502 COA D C1B 1 
HETATM 21338 C C2B . COA K 4 .   ? 0.089   90.585  -9.096  1.00 51.28  ? 502 COA D C2B 1 
HETATM 21339 O O2B . COA K 4 .   ? -0.638  89.917  -8.085  1.00 44.26  ? 502 COA D O2B 1 
HETATM 21340 C C3B . COA K 4 .   ? -0.258  92.062  -9.072  1.00 54.25  ? 502 COA D C3B 1 
HETATM 21341 O O3B . COA K 4 .   ? -1.656  91.999  -8.793  1.00 65.05  ? 502 COA D O3B 1 
HETATM 21342 P P3B . COA K 4 .   ? -2.327  93.319  -8.146  1.00 66.68  ? 502 COA D P3B 1 
HETATM 21343 O O7A . COA K 4 .   ? -1.640  93.532  -6.811  1.00 64.52  ? 502 COA D O7A 1 
HETATM 21344 O O8A . COA K 4 .   ? -3.821  92.985  -8.017  1.00 61.23  ? 502 COA D O8A 1 
HETATM 21345 O O9A . COA K 4 .   ? -2.057  94.456  -9.126  1.00 64.57  ? 502 COA D O9A 1 
HETATM 21346 C C4B . COA K 4 .   ? 0.104   92.536  -10.481 1.00 50.99  ? 502 COA D C4B 1 
HETATM 21347 O O4B . COA K 4 .   ? 0.099   91.343  -11.311 1.00 50.85  ? 502 COA D O4B 1 
HETATM 21348 C C5B . COA K 4 .   ? 1.432   93.250  -10.610 1.00 49.95  ? 502 COA D C5B 1 
HETATM 21349 O O5B . COA K 4 .   ? 2.510   92.443  -10.025 1.00 54.11  ? 502 COA D O5B 1 
HETATM 21350 P P1A . COA K 4 .   ? 3.979   92.309  -10.709 1.00 54.20  ? 502 COA D P1A 1 
HETATM 21351 O O1A . COA K 4 .   ? 4.740   93.600  -10.661 1.00 61.98  ? 502 COA D O1A 1 
HETATM 21352 O O2A . COA K 4 .   ? 3.887   91.662  -12.044 1.00 49.75  ? 502 COA D O2A 1 
HETATM 21353 O O3A . COA K 4 .   ? 4.675   91.284  -9.709  1.00 53.15  ? 502 COA D O3A 1 
HETATM 21354 P P2A . COA K 4 .   ? 5.159   91.332  -8.186  1.00 52.20  ? 502 COA D P2A 1 
HETATM 21355 O O4A . COA K 4 .   ? 6.587   91.737  -8.118  1.00 53.08  ? 502 COA D O4A 1 
HETATM 21356 O O5A . COA K 4 .   ? 4.147   91.970  -7.282  1.00 45.99  ? 502 COA D O5A 1 
HETATM 21357 O O6A . COA K 4 .   ? 5.033   89.766  -7.939  1.00 49.47  ? 502 COA D O6A 1 
HETATM 21358 C CBP . COA K 4 .   ? 5.655   87.499  -7.879  1.00 42.72  ? 502 COA D CBP 1 
HETATM 21359 C CCP . COA K 4 .   ? 6.184   88.912  -8.055  1.00 44.95  ? 502 COA D CCP 1 
HETATM 21360 C CDP . COA K 4 .   ? 6.761   86.476  -8.178  1.00 40.65  ? 502 COA D CDP 1 
HETATM 21361 C CEP . COA K 4 .   ? 5.152   87.303  -6.440  1.00 41.20  ? 502 COA D CEP 1 
HETATM 21362 C CAP . COA K 4 .   ? 4.488   87.411  -8.875  1.00 41.09  ? 502 COA D CAP 1 
HETATM 21363 O OAP . COA K 4 .   ? 4.904   87.391  -10.247 1.00 40.17  ? 502 COA D OAP 1 
HETATM 21364 C C9P . COA K 4 .   ? 3.682   86.188  -8.473  1.00 41.60  ? 502 COA D C9P 1 
HETATM 21365 O O9P . COA K 4 .   ? 2.859   86.335  -7.568  1.00 45.09  ? 502 COA D O9P 1 
HETATM 21366 N N8P . COA K 4 .   ? 3.979   85.008  -9.021  1.00 39.54  ? 502 COA D N8P 1 
HETATM 21367 C C7P . COA K 4 .   ? 3.352   83.743  -8.617  1.00 42.23  ? 502 COA D C7P 1 
HETATM 21368 C C6P . COA K 4 .   ? 4.098   82.956  -7.524  1.00 39.85  ? 502 COA D C6P 1 
HETATM 21369 C C5P . COA K 4 .   ? 5.418   82.396  -8.013  1.00 43.72  ? 502 COA D C5P 1 
HETATM 21370 O O5P . COA K 4 .   ? 5.433   81.514  -8.871  1.00 46.74  ? 502 COA D O5P 1 
HETATM 21371 N N4P . COA K 4 .   ? 6.549   82.939  -7.521  1.00 48.28  ? 502 COA D N4P 1 
HETATM 21372 C C3P . COA K 4 .   ? 7.902   82.529  -7.882  1.00 51.23  ? 502 COA D C3P 1 
HETATM 21373 C C2P . COA K 4 .   ? 8.962   83.570  -7.550  1.00 58.01  ? 502 COA D C2P 1 
HETATM 21374 S S1P . COA K 4 .   ? 10.585  83.137  -8.245  1.00 80.11  ? 502 COA D S1P 1 
HETATM 21375 O O1  . OAA L 2 .   ? 56.702  61.231  39.234  1.00 64.53  ? 501 OAA E O1  1 
HETATM 21376 O O2  . OAA L 2 .   ? 54.682  61.306  40.028  1.00 53.01  ? 501 OAA E O2  1 
HETATM 21377 O O4  . OAA L 2 .   ? 57.340  59.008  43.979  1.00 63.61  ? 501 OAA E O4  1 
HETATM 21378 O O5  . OAA L 2 .   ? 57.491  61.167  44.200  1.00 55.09  ? 501 OAA E O5  1 
HETATM 21379 O O3  . OAA L 2 .   ? 56.973  59.361  41.540  1.00 67.82  ? 501 OAA E O3  1 
HETATM 21380 C C1  . OAA L 2 .   ? 55.913  61.396  40.166  1.00 58.55  ? 501 OAA E C1  1 
HETATM 21381 C C2  . OAA L 2 .   ? 56.493  61.669  41.560  1.00 62.18  ? 501 OAA E C2  1 
HETATM 21382 C C3  . OAA L 2 .   ? 56.953  60.372  42.230  1.00 68.76  ? 501 OAA E C3  1 
HETATM 21383 C C4  . OAA L 2 .   ? 57.266  60.180  43.513  1.00 64.70  ? 501 OAA E C4  1 
HETATM 21384 O O1  . OAA M 2 .   ? 21.423  100.737 14.651  1.00 42.87  ? 501 OAA F O1  1 
HETATM 21385 O O2  . OAA M 2 .   ? 21.954  99.442  16.314  1.00 67.19  ? 501 OAA F O2  1 
HETATM 21386 O O4  . OAA M 2 .   ? 21.340  101.082 19.178  1.00 30.97  ? 501 OAA F O4  1 
HETATM 21387 O O5  . OAA M 2 .   ? 20.566  99.078  19.455  1.00 43.82  ? 501 OAA F O5  1 
HETATM 21388 O O3  . OAA M 2 .   ? 19.319  99.077  18.050  1.00 39.88  ? 501 OAA F O3  1 
HETATM 21389 C C1  . OAA M 2 .   ? 21.258  100.335 15.814  1.00 49.15  ? 501 OAA F C1  1 
HETATM 21390 C C2  . OAA M 2 .   ? 20.111  100.894 16.667  1.00 38.83  ? 501 OAA F C2  1 
HETATM 21391 C C3  . OAA M 2 .   ? 20.056  100.039 17.898  1.00 37.81  ? 501 OAA F C3  1 
HETATM 21392 C C4  . OAA M 2 .   ? 20.738  100.094 18.833  1.00 34.87  ? 501 OAA F C4  1 
HETATM 21393 N N1A . ACO N 3 .   ? 35.652  102.201 17.757  1.00 26.13  ? 502 ACO F N1A 1 
HETATM 21394 C C2A . ACO N 3 .   ? 36.443  102.244 16.680  1.00 28.06  ? 502 ACO F C2A 1 
HETATM 21395 N N3A . ACO N 3 .   ? 36.197  102.725 15.458  1.00 28.42  ? 502 ACO F N3A 1 
HETATM 21396 C C4A . ACO N 3 .   ? 34.954  103.217 15.387  1.00 29.36  ? 502 ACO F C4A 1 
HETATM 21397 C C5A . ACO N 3 .   ? 34.017  103.235 16.403  1.00 28.87  ? 502 ACO F C5A 1 
HETATM 21398 C C6A . ACO N 3 .   ? 34.401  102.703 17.647  1.00 29.31  ? 502 ACO F C6A 1 
HETATM 21399 N N6A . ACO N 3 .   ? 33.599  102.686 18.709  1.00 32.70  ? 502 ACO F N6A 1 
HETATM 21400 N N7A . ACO N 3 .   ? 32.839  103.821 15.968  1.00 26.06  ? 502 ACO F N7A 1 
HETATM 21401 C C8A . ACO N 3 .   ? 33.079  104.148 14.717  1.00 29.34  ? 502 ACO F C8A 1 
HETATM 21402 N N9A . ACO N 3 .   ? 34.362  103.803 14.301  1.00 30.09  ? 502 ACO F N9A 1 
HETATM 21403 C C1B . ACO N 3 .   ? 34.952  103.930 12.947  1.00 30.39  ? 502 ACO F C1B 1 
HETATM 21404 C C2B . ACO N 3 .   ? 34.413  102.894 11.957  1.00 29.03  ? 502 ACO F C2B 1 
HETATM 21405 O O2B . ACO N 3 .   ? 34.934  101.587 12.065  1.00 25.98  ? 502 ACO F O2B 1 
HETATM 21406 C C3B . ACO N 3 .   ? 34.811  103.556 10.642  1.00 29.38  ? 502 ACO F C3B 1 
HETATM 21407 O O3B . ACO N 3 .   ? 36.187  103.295 10.407  1.00 31.46  ? 502 ACO F O3B 1 
HETATM 21408 P P3B . ACO N 3 .   ? 36.521  102.959 8.849   1.00 35.14  ? 502 ACO F P3B 1 
HETATM 21409 O O7A . ACO N 3 .   ? 35.652  101.867 8.283   1.00 32.76  ? 502 ACO F O7A 1 
HETATM 21410 O O8A . ACO N 3 .   ? 37.989  102.537 8.866   1.00 30.65  ? 502 ACO F O8A 1 
HETATM 21411 O O9A . ACO N 3 .   ? 36.292  104.300 8.125   1.00 32.55  ? 502 ACO F O9A 1 
HETATM 21412 C C4B . ACO N 3 .   ? 34.525  105.029 10.935  1.00 32.04  ? 502 ACO F C4B 1 
HETATM 21413 O O4B . ACO N 3 .   ? 34.610  105.180 12.382  1.00 31.11  ? 502 ACO F O4B 1 
HETATM 21414 C C5B . ACO N 3 .   ? 33.173  105.516 10.461  1.00 32.49  ? 502 ACO F C5B 1 
HETATM 21415 O O5B . ACO N 3 .   ? 32.121  104.691 11.025  1.00 29.12  ? 502 ACO F O5B 1 
HETATM 21416 P P1A . ACO N 3 .   ? 30.842  105.389 11.681  1.00 32.96  ? 502 ACO F P1A 1 
HETATM 21417 O O1A . ACO N 3 .   ? 30.031  106.103 10.650  1.00 26.60  ? 502 ACO F O1A 1 
HETATM 21418 O O2A . ACO N 3 .   ? 31.233  106.196 12.874  1.00 32.31  ? 502 ACO F O2A 1 
HETATM 21419 O O3A . ACO N 3 .   ? 30.108  104.045 12.163  1.00 28.59  ? 502 ACO F O3A 1 
HETATM 21420 P P2A . ACO N 3 .   ? 28.909  103.237 11.482  1.00 27.66  ? 502 ACO F P2A 1 
HETATM 21421 O O4A . ACO N 3 .   ? 27.761  104.151 11.196  1.00 24.42  ? 502 ACO F O4A 1 
HETATM 21422 O O5A . ACO N 3 .   ? 29.500  102.323 10.469  1.00 27.60  ? 502 ACO F O5A 1 
HETATM 21423 O O6A . ACO N 3 .   ? 28.332  102.466 12.760  1.00 34.03  ? 502 ACO F O6A 1 
HETATM 21424 C CBP . ACO N 3 .   ? 28.985  101.204 14.717  1.00 30.66  ? 502 ACO F CBP 1 
HETATM 21425 C CCP . ACO N 3 .   ? 28.963  101.263 13.194  1.00 32.98  ? 502 ACO F CCP 1 
HETATM 21426 C CDP . ACO N 3 .   ? 27.803  101.926 15.355  1.00 31.93  ? 502 ACO F CDP 1 
HETATM 21427 C CEP . ACO N 3 .   ? 28.862  99.725  15.083  1.00 32.49  ? 502 ACO F CEP 1 
HETATM 21428 C CAP . ACO N 3 .   ? 30.295  101.840 15.206  1.00 27.74  ? 502 ACO F CAP 1 
HETATM 21429 O OAP . ACO N 3 .   ? 30.060  103.025 15.940  1.00 26.23  ? 502 ACO F OAP 1 
HETATM 21430 C C9P . ACO N 3 .   ? 31.048  100.800 16.013  1.00 25.72  ? 502 ACO F C9P 1 
HETATM 21431 O O9P . ACO N 3 .   ? 31.690  99.959  15.401  1.00 27.57  ? 502 ACO F O9P 1 
HETATM 21432 N N8P . ACO N 3 .   ? 30.890  100.770 17.326  1.00 27.94  ? 502 ACO F N8P 1 
HETATM 21433 C C7P . ACO N 3 .   ? 31.302  99.644  18.153  1.00 29.46  ? 502 ACO F C7P 1 
HETATM 21434 C C6P . ACO N 3 .   ? 30.169  98.636  18.331  1.00 33.08  ? 502 ACO F C6P 1 
HETATM 21435 C C5P . ACO N 3 .   ? 29.243  98.991  19.464  1.00 34.49  ? 502 ACO F C5P 1 
HETATM 21436 O O5P . ACO N 3 .   ? 29.672  99.658  20.399  1.00 36.89  ? 502 ACO F O5P 1 
HETATM 21437 N N4P . ACO N 3 .   ? 27.930  98.781  19.345  1.00 39.87  ? 502 ACO F N4P 1 
HETATM 21438 C C3P . ACO N 3 .   ? 27.125  99.251  18.237  1.00 50.08  ? 502 ACO F C3P 1 
HETATM 21439 C C2P . ACO N 3 .   ? 26.294  100.471 18.629  1.00 56.85  ? 502 ACO F C2P 1 
HETATM 21440 S S1P . ACO N 3 .   ? 24.803  100.155 19.654  1.00 59.63  ? 502 ACO F S1P 1 
HETATM 21441 C C   . ACO N 3 .   ? 23.778  98.568  19.425  1.00 88.07  ? 502 ACO F C   1 
HETATM 21442 O O   . ACO N 3 .   ? 23.031  98.246  20.332  1.00 90.21  ? 502 ACO F O   1 
HETATM 21443 C CH3 . ACO N 3 .   ? 23.872  97.707  18.105  1.00 84.83  ? 502 ACO F CH3 1 
HETATM 21444 O O   . HOH O 5 .   ? 0.073   9.061   29.675  1.00 51.69  ? 601 HOH A O   1 
HETATM 21445 O O   . HOH O 5 .   ? 8.520   2.031   24.935  1.00 46.37  ? 602 HOH A O   1 
HETATM 21446 O O   . HOH O 5 .   ? 24.716  20.996  37.247  1.00 40.57  ? 603 HOH A O   1 
HETATM 21447 O O   . HOH O 5 .   ? 16.571  39.062  -3.759  1.00 39.27  ? 604 HOH A O   1 
HETATM 21448 O O   . HOH O 5 .   ? 9.429   48.392  1.878   1.00 32.11  ? 605 HOH A O   1 
HETATM 21449 O O   . HOH O 5 .   ? -0.797  49.004  -2.564  1.00 44.05  ? 606 HOH A O   1 
HETATM 21450 O O   . HOH O 5 .   ? 23.194  3.046   33.498  1.00 51.65  ? 607 HOH A O   1 
HETATM 21451 O O   . HOH O 5 .   ? -1.880  11.697  13.990  1.00 39.06  ? 608 HOH A O   1 
HETATM 21452 O O   . HOH O 5 .   ? 30.147  41.991  11.657  1.00 35.69  ? 609 HOH A O   1 
HETATM 21453 O O   . HOH O 5 .   ? -5.250  50.521  -5.513  1.00 42.52  ? 610 HOH A O   1 
HETATM 21454 O O   . HOH O 5 .   ? 7.448   47.551  6.830   1.00 20.64  ? 611 HOH A O   1 
HETATM 21455 O O   . HOH O 5 .   ? 15.242  54.891  30.304  1.00 31.33  ? 612 HOH A O   1 
HETATM 21456 O O   . HOH O 5 .   ? 6.053   20.919  -3.556  1.00 33.11  ? 613 HOH A O   1 
HETATM 21457 O O   . HOH O 5 .   ? 29.747  48.165  20.105  1.00 30.88  ? 614 HOH A O   1 
HETATM 21458 O O   . HOH O 5 .   ? -19.990 35.716  27.882  1.00 24.56  ? 615 HOH A O   1 
HETATM 21459 O O   . HOH O 5 .   ? 15.898  22.063  26.562  1.00 29.15  ? 616 HOH A O   1 
HETATM 21460 O O   . HOH O 5 .   ? 2.636   27.991  13.979  1.00 30.03  ? 617 HOH A O   1 
HETATM 21461 O O   . HOH O 5 .   ? -16.310 18.358  25.131  1.00 41.13  ? 618 HOH A O   1 
HETATM 21462 O O   . HOH O 5 .   ? -1.877  48.203  11.776  1.00 26.26  ? 619 HOH A O   1 
HETATM 21463 O O   . HOH O 5 .   ? -5.217  40.296  -0.701  1.00 33.26  ? 620 HOH A O   1 
HETATM 21464 O O   . HOH O 5 .   ? 19.994  47.908  10.888  1.00 29.50  ? 621 HOH A O   1 
HETATM 21465 O O   . HOH O 5 .   ? 25.459  42.664  17.400  1.00 21.75  ? 622 HOH A O   1 
HETATM 21466 O O   . HOH O 5 .   ? 21.012  37.534  5.822   1.00 52.32  ? 623 HOH A O   1 
HETATM 21467 O O   . HOH O 5 .   ? -11.728 33.894  -0.821  1.00 38.31  ? 624 HOH A O   1 
HETATM 21468 O O   . HOH O 5 .   ? 16.945  55.719  24.345  1.00 26.92  ? 625 HOH A O   1 
HETATM 21469 O O   . HOH O 5 .   ? 2.781   54.454  13.769  1.00 24.99  ? 626 HOH A O   1 
HETATM 21470 O O   . HOH O 5 .   ? -2.414  28.035  0.440   1.00 35.93  ? 627 HOH A O   1 
HETATM 21471 O O   . HOH O 5 .   ? 14.100  45.689  8.278   1.00 29.02  ? 628 HOH A O   1 
HETATM 21472 O O   . HOH O 5 .   ? -19.092 15.651  10.435  1.00 49.09  ? 629 HOH A O   1 
HETATM 21473 O O   . HOH O 5 .   ? 14.628  32.396  -8.301  1.00 42.01  ? 630 HOH A O   1 
HETATM 21474 O O   . HOH O 5 .   ? 5.229   25.954  22.684  1.00 33.29  ? 631 HOH A O   1 
HETATM 21475 O O   . HOH O 5 .   ? -14.460 23.311  11.483  1.00 26.18  ? 632 HOH A O   1 
HETATM 21476 O O   . HOH O 5 .   ? 11.152  47.899  30.302  1.00 23.41  ? 633 HOH A O   1 
HETATM 21477 O O   . HOH O 5 .   ? -19.835 25.545  23.773  1.00 25.09  ? 634 HOH A O   1 
HETATM 21478 O O   . HOH O 5 .   ? -9.912  40.839  3.718   1.00 34.33  ? 635 HOH A O   1 
HETATM 21479 O O   . HOH O 5 .   ? 10.050  53.436  5.805   1.00 37.08  ? 636 HOH A O   1 
HETATM 21480 O O   . HOH O 5 .   ? -6.292  36.710  10.173  1.00 22.39  ? 637 HOH A O   1 
HETATM 21481 O O   . HOH O 5 .   ? 23.498  43.749  4.887   1.00 40.59  ? 638 HOH A O   1 
HETATM 21482 O O   . HOH O 5 .   ? 19.503  30.982  7.555   1.00 32.83  ? 639 HOH A O   1 
HETATM 21483 O O   . HOH O 5 .   ? 7.800   20.154  28.369  1.00 39.52  ? 640 HOH A O   1 
HETATM 21484 O O   . HOH O 5 .   ? 5.003   42.351  -2.163  1.00 43.61  ? 641 HOH A O   1 
HETATM 21485 O O   . HOH O 5 .   ? 26.759  21.084  1.444   1.00 40.78  ? 642 HOH A O   1 
HETATM 21486 O O   . HOH O 5 .   ? 19.805  30.548  36.545  1.00 51.87  ? 643 HOH A O   1 
HETATM 21487 O O   . HOH O 5 .   ? 17.557  46.889  25.432  1.00 21.15  ? 644 HOH A O   1 
HETATM 21488 O O   . HOH O 5 .   ? 7.937   15.849  10.738  1.00 35.46  ? 645 HOH A O   1 
HETATM 21489 O O   . HOH O 5 .   ? -0.792  41.291  10.774  1.00 28.95  ? 646 HOH A O   1 
HETATM 21490 O O   . HOH O 5 .   ? -11.408 28.228  28.431  1.00 33.69  ? 647 HOH A O   1 
HETATM 21491 O O   . HOH O 5 .   ? -7.342  40.826  3.090   1.00 32.19  ? 648 HOH A O   1 
HETATM 21492 O O   . HOH O 5 .   ? -10.313 40.487  8.284   1.00 27.73  ? 649 HOH A O   1 
HETATM 21493 O O   . HOH O 5 .   ? -6.219  38.474  -2.494  1.00 36.77  ? 650 HOH A O   1 
HETATM 21494 O O   . HOH O 5 .   ? 10.788  26.766  25.210  1.00 46.48  ? 651 HOH A O   1 
HETATM 21495 O O   . HOH O 5 .   ? 20.088  54.678  21.078  1.00 31.82  ? 652 HOH A O   1 
HETATM 21496 O O   . HOH O 5 .   ? 25.140  20.929  26.857  1.00 38.68  ? 653 HOH A O   1 
HETATM 21497 O O   . HOH O 5 .   ? 19.766  57.932  18.546  1.00 26.90  ? 654 HOH A O   1 
HETATM 21498 O O   . HOH O 5 .   ? -9.297  35.571  -6.833  1.00 48.83  ? 655 HOH A O   1 
HETATM 21499 O O   . HOH O 5 .   ? 13.317  22.778  35.736  1.00 34.05  ? 656 HOH A O   1 
HETATM 21500 O O   . HOH O 5 .   ? -3.699  22.902  2.578   1.00 32.95  ? 657 HOH A O   1 
HETATM 21501 O O   . HOH O 5 .   ? -10.322 34.485  10.347  1.00 25.85  ? 658 HOH A O   1 
HETATM 21502 O O   . HOH O 5 .   ? 30.537  28.671  20.240  1.00 35.05  ? 659 HOH A O   1 
HETATM 21503 O O   . HOH O 5 .   ? 13.323  27.585  22.778  1.00 44.12  ? 660 HOH A O   1 
HETATM 21504 O O   . HOH O 5 .   ? 12.764  25.069  22.111  1.00 33.17  ? 661 HOH A O   1 
HETATM 21505 O O   . HOH O 5 .   ? 12.564  32.995  31.506  1.00 35.79  ? 662 HOH A O   1 
HETATM 21506 O O   . HOH O 5 .   ? 22.039  44.866  16.629  1.00 23.50  ? 663 HOH A O   1 
HETATM 21507 O O   . HOH O 5 .   ? 12.322  13.078  42.787  1.00 41.90  ? 664 HOH A O   1 
HETATM 21508 O O   . HOH O 5 .   ? 23.604  49.224  28.234  1.00 22.87  ? 665 HOH A O   1 
HETATM 21509 O O   . HOH O 5 .   ? 9.845   58.199  7.947   1.00 30.35  ? 666 HOH A O   1 
HETATM 21510 O O   . HOH O 5 .   ? -3.171  30.252  9.186   1.00 20.65  ? 667 HOH A O   1 
HETATM 21511 O O   . HOH O 5 .   ? 1.101   23.075  23.287  1.00 40.12  ? 668 HOH A O   1 
HETATM 21512 O O   . HOH O 5 .   ? 1.709   44.051  7.766   1.00 22.93  ? 669 HOH A O   1 
HETATM 21513 O O   . HOH O 5 .   ? 7.548   54.201  17.046  1.00 25.35  ? 670 HOH A O   1 
HETATM 21514 O O   . HOH O 5 .   ? 23.840  44.944  14.821  1.00 34.39  ? 671 HOH A O   1 
HETATM 21515 O O   . HOH O 5 .   ? -8.734  33.300  12.764  1.00 38.70  ? 672 HOH A O   1 
HETATM 21516 O O   . HOH O 5 .   ? 19.737  51.931  4.902   1.00 36.47  ? 673 HOH A O   1 
HETATM 21517 O O   . HOH O 5 .   ? -3.620  48.534  9.466   1.00 23.15  ? 674 HOH A O   1 
HETATM 21518 O O   . HOH O 5 .   ? -11.448 31.246  12.428  1.00 25.16  ? 675 HOH A O   1 
HETATM 21519 O O   . HOH O 5 .   ? 18.048  20.340  4.102   1.00 32.67  ? 676 HOH A O   1 
HETATM 21520 O O   . HOH O 5 .   ? 7.860   56.501  7.988   1.00 35.59  ? 677 HOH A O   1 
HETATM 21521 O O   . HOH O 5 .   ? -14.087 36.869  2.134   1.00 32.89  ? 678 HOH A O   1 
HETATM 21522 O O   . HOH O 5 .   ? 22.235  51.454  29.427  1.00 26.54  ? 679 HOH A O   1 
HETATM 21523 O O   . HOH O 5 .   ? 18.465  37.694  31.763  1.00 36.02  ? 680 HOH A O   1 
HETATM 21524 O O   . HOH O 5 .   ? -0.259  32.865  12.447  1.00 35.53  ? 681 HOH A O   1 
HETATM 21525 O O   . HOH O 5 .   ? 18.199  52.542  30.169  1.00 34.54  ? 682 HOH A O   1 
HETATM 21526 O O   . HOH O 5 .   ? -14.738 42.995  2.898   1.00 35.26  ? 683 HOH A O   1 
HETATM 21527 O O   . HOH O 5 .   ? 4.877   4.272   45.287  1.00 41.16  ? 684 HOH A O   1 
HETATM 21528 O O   . HOH O 5 .   ? 26.749  45.835  8.006   1.00 27.92  ? 685 HOH A O   1 
HETATM 21529 O O   . HOH O 5 .   ? 24.006  44.525  18.407  1.00 27.62  ? 686 HOH A O   1 
HETATM 21530 O O   . HOH O 5 .   ? 24.527  47.121  29.214  1.00 34.30  ? 687 HOH A O   1 
HETATM 21531 O O   . HOH O 5 .   ? 31.086  38.028  15.983  1.00 38.07  ? 688 HOH A O   1 
HETATM 21532 O O   . HOH O 5 .   ? -28.461 30.729  36.047  1.00 51.92  ? 689 HOH A O   1 
HETATM 21533 O O   . HOH O 5 .   ? -0.004  26.872  22.424  1.00 40.77  ? 690 HOH A O   1 
HETATM 21534 O O   . HOH O 5 .   ? -13.391 43.948  5.266   1.00 40.98  ? 691 HOH A O   1 
HETATM 21535 O O   . HOH O 5 .   ? 22.494  50.804  8.170   1.00 38.91  ? 692 HOH A O   1 
HETATM 21536 O O   . HOH O 5 .   ? -2.457  29.658  6.637   1.00 30.98  ? 693 HOH A O   1 
HETATM 21537 O O   . HOH O 5 .   ? -30.793 32.513  34.859  1.00 35.14  ? 694 HOH A O   1 
HETATM 21538 O O   . HOH O 5 .   ? 28.418  28.089  7.042   1.00 35.26  ? 695 HOH A O   1 
HETATM 21539 O O   . HOH O 5 .   ? 20.040  52.781  12.663  1.00 38.96  ? 696 HOH A O   1 
HETATM 21540 O O   . HOH O 5 .   ? 13.124  48.270  4.508   1.00 39.69  ? 697 HOH A O   1 
HETATM 21541 O O   . HOH O 5 .   ? 2.741   13.872  24.183  1.00 44.38  ? 698 HOH A O   1 
HETATM 21542 O O   . HOH O 5 .   ? -12.799 36.463  -2.055  1.00 32.39  ? 699 HOH A O   1 
HETATM 21543 O O   . HOH O 5 .   ? 31.524  25.141  31.583  1.00 44.34  ? 700 HOH A O   1 
HETATM 21544 O O   . HOH O 5 .   ? 12.813  28.798  25.372  1.00 37.83  ? 701 HOH A O   1 
HETATM 21545 O O   . HOH O 5 .   ? 17.960  39.857  33.257  1.00 33.44  ? 702 HOH A O   1 
HETATM 21546 O O   . HOH O 5 .   ? 3.187   12.105  27.357  1.00 38.51  ? 703 HOH A O   1 
HETATM 21547 O O   . HOH O 5 .   ? 31.197  30.196  17.981  1.00 35.33  ? 704 HOH A O   1 
HETATM 21548 O O   . HOH O 5 .   ? 15.650  14.524  10.488  1.00 36.48  ? 705 HOH A O   1 
HETATM 21549 O O   . HOH O 5 .   ? -9.435  53.382  4.914   1.00 39.46  ? 706 HOH A O   1 
HETATM 21550 O O   . HOH O 5 .   ? 28.653  23.905  32.620  1.00 41.98  ? 707 HOH A O   1 
HETATM 21551 O O   . HOH O 5 .   ? 0.206   27.552  -11.359 1.00 38.55  ? 708 HOH A O   1 
HETATM 21552 O O   . HOH O 5 .   ? 23.317  39.759  32.606  1.00 37.18  ? 709 HOH A O   1 
HETATM 21553 O O   . HOH O 5 .   ? 12.833  47.901  7.173   1.00 40.73  ? 710 HOH A O   1 
HETATM 21554 O O   . HOH O 5 .   ? 8.652   21.932  32.976  1.00 40.52  ? 711 HOH A O   1 
HETATM 21555 O O   . HOH O 5 .   ? -7.946  31.404  10.398  1.00 34.18  ? 712 HOH A O   1 
HETATM 21556 O O   . HOH O 5 .   ? 20.678  40.642  32.182  1.00 38.40  ? 713 HOH A O   1 
HETATM 21557 O O   . HOH O 5 .   ? -26.531 29.549  42.652  1.00 50.51  ? 714 HOH A O   1 
HETATM 21558 O O   . HOH O 5 .   ? 12.030  50.074  2.780   1.00 35.49  ? 715 HOH A O   1 
HETATM 21559 O O   . HOH O 5 .   ? -7.500  34.107  10.303  1.00 27.43  ? 716 HOH A O   1 
HETATM 21560 O O   . HOH O 5 .   ? 3.221   3.309   43.529  1.00 37.78  ? 717 HOH A O   1 
HETATM 21561 O O   . HOH P 5 .   ? -34.630 57.949  35.074  1.00 30.69  ? 601 HOH B O   1 
HETATM 21562 O O   . HOH P 5 .   ? -4.722  26.547  48.190  1.00 40.84  ? 602 HOH B O   1 
HETATM 21563 O O   . HOH P 5 .   ? -19.039 69.196  8.541   1.00 45.96  ? 603 HOH B O   1 
HETATM 21564 O O   . HOH P 5 .   ? -5.760  70.254  33.225  1.00 18.05  ? 604 HOH B O   1 
HETATM 21565 O O   . HOH P 5 .   ? -4.395  30.516  37.440  1.00 41.71  ? 605 HOH B O   1 
HETATM 21566 O O   . HOH P 5 .   ? -27.891 58.382  15.610  1.00 21.47  ? 606 HOH B O   1 
HETATM 21567 O O   . HOH P 5 .   ? 4.235   37.558  32.142  1.00 24.15  ? 607 HOH B O   1 
HETATM 21568 O O   . HOH P 5 .   ? -8.330  69.248  20.755  1.00 37.86  ? 608 HOH B O   1 
HETATM 21569 O O   . HOH P 5 .   ? -17.313 58.045  7.735   1.00 32.53  ? 609 HOH B O   1 
HETATM 21570 O O   . HOH P 5 .   ? -34.604 57.432  31.422  1.00 35.68  ? 610 HOH B O   1 
HETATM 21571 O O   . HOH P 5 .   ? -15.317 42.945  26.085  1.00 29.91  ? 611 HOH B O   1 
HETATM 21572 O O   . HOH P 5 .   ? -17.769 54.441  20.972  1.00 30.04  ? 612 HOH B O   1 
HETATM 21573 O O   . HOH P 5 .   ? 13.767  58.504  25.680  1.00 24.88  ? 613 HOH B O   1 
HETATM 21574 O O   . HOH P 5 .   ? -25.508 46.591  23.935  1.00 29.76  ? 614 HOH B O   1 
HETATM 21575 O O   . HOH P 5 .   ? -31.348 53.654  42.187  1.00 36.40  ? 615 HOH B O   1 
HETATM 21576 O O   . HOH P 5 .   ? -0.720  65.431  31.413  1.00 22.14  ? 616 HOH B O   1 
HETATM 21577 O O   . HOH P 5 .   ? -26.733 24.186  8.200   1.00 41.88  ? 617 HOH B O   1 
HETATM 21578 O O   . HOH P 5 .   ? -20.250 69.831  18.030  1.00 56.40  ? 618 HOH B O   1 
HETATM 21579 O O   . HOH P 5 .   ? -19.588 53.956  40.860  1.00 24.60  ? 619 HOH B O   1 
HETATM 21580 O O   . HOH P 5 .   ? 2.310   50.835  42.134  1.00 36.09  ? 620 HOH B O   1 
HETATM 21581 O O   . HOH P 5 .   ? -19.044 48.229  26.596  1.00 25.81  ? 621 HOH B O   1 
HETATM 21582 O O   . HOH P 5 .   ? -11.791 37.556  19.007  1.00 19.05  ? 622 HOH B O   1 
HETATM 21583 O O   . HOH P 5 .   ? -7.262  69.750  39.288  1.00 34.50  ? 623 HOH B O   1 
HETATM 21584 O O   . HOH P 5 .   ? -3.344  25.093  30.509  1.00 31.30  ? 624 HOH B O   1 
HETATM 21585 O O   . HOH P 5 .   ? 14.568  60.600  31.642  1.00 25.28  ? 625 HOH B O   1 
HETATM 21586 O O   . HOH P 5 .   ? 7.605   48.043  41.015  1.00 31.47  ? 626 HOH B O   1 
HETATM 21587 O O   . HOH P 5 .   ? -11.681 28.386  25.313  1.00 26.23  ? 627 HOH B O   1 
HETATM 21588 O O   . HOH P 5 .   ? -13.507 21.946  30.167  1.00 36.19  ? 628 HOH B O   1 
HETATM 21589 O O   . HOH P 5 .   ? -17.129 30.763  6.474   1.00 41.16  ? 629 HOH B O   1 
HETATM 21590 O O   . HOH P 5 .   ? -25.379 63.726  33.538  1.00 28.82  ? 630 HOH B O   1 
HETATM 21591 O O   . HOH P 5 .   ? 0.197   61.045  14.160  1.00 18.17  ? 631 HOH B O   1 
HETATM 21592 O O   . HOH P 5 .   ? -10.323 70.049  38.825  1.00 38.96  ? 632 HOH B O   1 
HETATM 21593 O O   . HOH P 5 .   ? -27.065 72.673  23.927  1.00 35.80  ? 633 HOH B O   1 
HETATM 21594 O O   . HOH P 5 .   ? -4.565  16.773  5.026   1.00 61.63  ? 634 HOH B O   1 
HETATM 21595 O O   . HOH P 5 .   ? -32.566 67.051  15.368  1.00 48.41  ? 635 HOH B O   1 
HETATM 21596 O O   . HOH P 5 .   ? -32.586 12.525  11.418  1.00 32.44  ? 636 HOH B O   1 
HETATM 21597 O O   . HOH P 5 .   ? -7.041  33.309  29.883  1.00 26.11  ? 637 HOH B O   1 
HETATM 21598 O O   . HOH P 5 .   ? -0.531  40.430  35.790  1.00 23.67  ? 638 HOH B O   1 
HETATM 21599 O O   . HOH P 5 .   ? -2.738  38.528  31.870  1.00 23.23  ? 639 HOH B O   1 
HETATM 21600 O O   . HOH P 5 .   ? -26.211 18.516  13.064  1.00 48.49  ? 640 HOH B O   1 
HETATM 21601 O O   . HOH P 5 .   ? -11.996 25.469  38.288  1.00 29.82  ? 641 HOH B O   1 
HETATM 21602 O O   . HOH P 5 .   ? -10.629 39.935  28.166  1.00 32.32  ? 642 HOH B O   1 
HETATM 21603 O O   . HOH P 5 .   ? 12.981  37.047  42.818  1.00 42.85  ? 643 HOH B O   1 
HETATM 21604 O O   . HOH P 5 .   ? -34.867 55.946  23.417  1.00 34.90  ? 644 HOH B O   1 
HETATM 21605 O O   . HOH P 5 .   ? -28.391 47.349  29.708  1.00 23.89  ? 645 HOH B O   1 
HETATM 21606 O O   . HOH P 5 .   ? -3.555  23.185  9.859   1.00 38.35  ? 646 HOH B O   1 
HETATM 21607 O O   . HOH P 5 .   ? -5.873  32.109  41.035  1.00 26.23  ? 647 HOH B O   1 
HETATM 21608 O O   . HOH P 5 .   ? -13.501 49.603  13.200  1.00 36.54  ? 648 HOH B O   1 
HETATM 21609 O O   . HOH P 5 .   ? -29.630 60.469  19.748  1.00 25.13  ? 649 HOH B O   1 
HETATM 21610 O O   . HOH P 5 .   ? -12.590 55.005  18.264  1.00 31.65  ? 650 HOH B O   1 
HETATM 21611 O O   . HOH P 5 .   ? -1.813  68.059  40.991  1.00 37.20  ? 651 HOH B O   1 
HETATM 21612 O O   . HOH P 5 .   ? -26.089 48.754  14.817  1.00 32.37  ? 652 HOH B O   1 
HETATM 21613 O O   . HOH P 5 .   ? -11.729 32.618  9.582   1.00 26.32  ? 653 HOH B O   1 
HETATM 21614 O O   . HOH P 5 .   ? -23.373 15.820  30.746  1.00 37.27  ? 654 HOH B O   1 
HETATM 21615 O O   . HOH P 5 .   ? 10.808  42.706  32.386  1.00 22.09  ? 655 HOH B O   1 
HETATM 21616 O O   . HOH P 5 .   ? -13.561 36.169  30.772  1.00 28.12  ? 656 HOH B O   1 
HETATM 21617 O O   . HOH P 5 .   ? 13.254  48.869  39.934  1.00 32.80  ? 657 HOH B O   1 
HETATM 21618 O O   . HOH P 5 .   ? -36.584 69.515  2.933   1.00 35.74  ? 658 HOH B O   1 
HETATM 21619 O O   . HOH P 5 .   ? -20.449 61.384  38.975  1.00 25.49  ? 659 HOH B O   1 
HETATM 21620 O O   . HOH P 5 .   ? -10.763 72.967  31.100  1.00 38.22  ? 660 HOH B O   1 
HETATM 21621 O O   . HOH P 5 .   ? 3.136   74.083  24.174  1.00 32.87  ? 661 HOH B O   1 
HETATM 21622 O O   . HOH P 5 .   ? -0.784  49.128  18.847  1.00 21.84  ? 662 HOH B O   1 
HETATM 21623 O O   . HOH P 5 .   ? 14.103  58.480  19.171  1.00 22.79  ? 663 HOH B O   1 
HETATM 21624 O O   . HOH P 5 .   ? -4.051  28.752  31.730  1.00 29.89  ? 664 HOH B O   1 
HETATM 21625 O O   . HOH P 5 .   ? -8.251  30.123  42.507  1.00 34.35  ? 665 HOH B O   1 
HETATM 21626 O O   . HOH P 5 .   ? -24.371 40.366  32.669  1.00 30.78  ? 666 HOH B O   1 
HETATM 21627 O O   . HOH P 5 .   ? 6.690   40.349  26.048  1.00 26.19  ? 667 HOH B O   1 
HETATM 21628 O O   . HOH P 5 .   ? -24.854 63.926  43.471  1.00 34.62  ? 668 HOH B O   1 
HETATM 21629 O O   . HOH P 5 .   ? -29.331 55.127  31.492  1.00 31.37  ? 669 HOH B O   1 
HETATM 21630 O O   . HOH P 5 .   ? -30.873 46.253  28.695  1.00 39.06  ? 670 HOH B O   1 
HETATM 21631 O O   . HOH P 5 .   ? 5.391   70.167  30.712  1.00 26.26  ? 671 HOH B O   1 
HETATM 21632 O O   . HOH P 5 .   ? -9.397  67.334  14.533  1.00 34.18  ? 672 HOH B O   1 
HETATM 21633 O O   . HOH P 5 .   ? -22.117 71.678  27.004  1.00 34.21  ? 673 HOH B O   1 
HETATM 21634 O O   . HOH P 5 .   ? -8.550  73.731  32.604  1.00 39.76  ? 674 HOH B O   1 
HETATM 21635 O O   . HOH P 5 .   ? -20.763 50.956  13.762  1.00 44.09  ? 675 HOH B O   1 
HETATM 21636 O O   . HOH P 5 .   ? -32.439 38.537  24.284  1.00 33.08  ? 676 HOH B O   1 
HETATM 21637 O O   . HOH P 5 .   ? -6.307  21.359  20.214  1.00 45.45  ? 677 HOH B O   1 
HETATM 21638 O O   . HOH P 5 .   ? 6.028   63.546  10.927  1.00 30.31  ? 678 HOH B O   1 
HETATM 21639 O O   . HOH P 5 .   ? -3.695  41.575  45.514  1.00 26.56  ? 679 HOH B O   1 
HETATM 21640 O O   . HOH P 5 .   ? 5.612   67.107  20.535  1.00 26.71  ? 680 HOH B O   1 
HETATM 21641 O O   . HOH P 5 .   ? -14.145 71.282  27.392  1.00 31.42  ? 681 HOH B O   1 
HETATM 21642 O O   . HOH P 5 .   ? -34.779 62.294  17.734  1.00 36.90  ? 682 HOH B O   1 
HETATM 21643 O O   . HOH P 5 .   ? -18.905 37.107  22.681  1.00 22.75  ? 683 HOH B O   1 
HETATM 21644 O O   . HOH P 5 .   ? -9.883  30.471  25.895  1.00 39.77  ? 684 HOH B O   1 
HETATM 21645 O O   . HOH P 5 .   ? -7.242  55.287  15.830  1.00 23.99  ? 685 HOH B O   1 
HETATM 21646 O O   . HOH P 5 .   ? 3.356   58.635  37.929  1.00 35.14  ? 686 HOH B O   1 
HETATM 21647 O O   . HOH P 5 .   ? 11.707  60.904  28.996  1.00 34.96  ? 687 HOH B O   1 
HETATM 21648 O O   . HOH P 5 .   ? -11.179 48.025  54.282  1.00 44.14  ? 688 HOH B O   1 
HETATM 21649 O O   . HOH P 5 .   ? -7.775  59.126  40.352  1.00 36.10  ? 689 HOH B O   1 
HETATM 21650 O O   . HOH P 5 .   ? -15.739 20.794  41.991  1.00 29.84  ? 690 HOH B O   1 
HETATM 21651 O O   . HOH P 5 .   ? -8.470  51.172  15.622  1.00 44.61  ? 691 HOH B O   1 
HETATM 21652 O O   . HOH P 5 .   ? -21.215 60.355  17.209  1.00 30.49  ? 692 HOH B O   1 
HETATM 21653 O O   . HOH P 5 .   ? -11.636 25.750  45.573  1.00 40.46  ? 693 HOH B O   1 
HETATM 21654 O O   . HOH P 5 .   ? 8.378   59.083  36.413  1.00 33.52  ? 694 HOH B O   1 
HETATM 21655 O O   . HOH P 5 .   ? -7.717  49.867  49.720  1.00 35.58  ? 695 HOH B O   1 
HETATM 21656 O O   . HOH P 5 .   ? -16.279 64.485  6.917   1.00 48.10  ? 696 HOH B O   1 
HETATM 21657 O O   . HOH P 5 .   ? -32.714 66.663  19.003  1.00 38.25  ? 697 HOH B O   1 
HETATM 21658 O O   . HOH P 5 .   ? -17.749 53.223  9.157   1.00 43.94  ? 698 HOH B O   1 
HETATM 21659 O O   . HOH P 5 .   ? -12.543 31.984  28.344  1.00 31.88  ? 699 HOH B O   1 
HETATM 21660 O O   . HOH P 5 .   ? -1.993  73.706  29.123  1.00 34.51  ? 700 HOH B O   1 
HETATM 21661 O O   . HOH P 5 .   ? -22.807 50.208  10.081  1.00 44.77  ? 701 HOH B O   1 
HETATM 21662 O O   . HOH P 5 .   ? -6.593  62.170  14.186  1.00 30.69  ? 702 HOH B O   1 
HETATM 21663 O O   . HOH P 5 .   ? -13.880 62.736  42.662  1.00 40.30  ? 703 HOH B O   1 
HETATM 21664 O O   . HOH P 5 .   ? -25.947 24.001  15.613  1.00 33.19  ? 704 HOH B O   1 
HETATM 21665 O O   . HOH P 5 .   ? -16.013 62.907  44.493  1.00 26.75  ? 705 HOH B O   1 
HETATM 21666 O O   . HOH P 5 .   ? -30.843 70.900  28.948  1.00 33.67  ? 706 HOH B O   1 
HETATM 21667 O O   . HOH P 5 .   ? -16.583 73.011  36.032  1.00 46.18  ? 707 HOH B O   1 
HETATM 21668 O O   . HOH P 5 .   ? -15.069 53.954  20.595  1.00 32.91  ? 708 HOH B O   1 
HETATM 21669 O O   . HOH P 5 .   ? 0.821   63.186  34.046  1.00 45.31  ? 709 HOH B O   1 
HETATM 21670 O O   . HOH P 5 .   ? -11.415 23.676  36.529  1.00 34.51  ? 710 HOH B O   1 
HETATM 21671 O O   . HOH P 5 .   ? -29.128 73.674  10.950  1.00 42.72  ? 711 HOH B O   1 
HETATM 21672 O O   . HOH P 5 .   ? -14.918 52.993  17.908  1.00 25.90  ? 712 HOH B O   1 
HETATM 21673 O O   . HOH P 5 .   ? -15.206 50.463  17.266  1.00 43.83  ? 713 HOH B O   1 
HETATM 21674 O O   . HOH P 5 .   ? -33.302 68.833  26.361  1.00 29.90  ? 714 HOH B O   1 
HETATM 21675 O O   . HOH P 5 .   ? -17.437 50.273  21.039  1.00 42.27  ? 715 HOH B O   1 
HETATM 21676 O O   . HOH P 5 .   ? -32.516 38.324  30.861  1.00 43.90  ? 716 HOH B O   1 
HETATM 21677 O O   . HOH P 5 .   ? 0.647   69.936  36.814  1.00 31.50  ? 717 HOH B O   1 
HETATM 21678 O O   . HOH P 5 .   ? 4.970   59.391  22.788  1.00 25.70  ? 718 HOH B O   1 
HETATM 21679 O O   . HOH P 5 .   ? -29.648 53.012  28.955  1.00 34.39  ? 719 HOH B O   1 
HETATM 21680 O O   . HOH P 5 .   ? -7.894  31.668  46.622  1.00 42.39  ? 720 HOH B O   1 
HETATM 21681 O O   . HOH P 5 .   ? -27.161 21.521  21.258  1.00 48.35  ? 721 HOH B O   1 
HETATM 21682 O O   . HOH P 5 .   ? -22.602 30.066  14.433  1.00 34.93  ? 722 HOH B O   1 
HETATM 21683 O O   . HOH P 5 .   ? -36.709 56.063  17.083  1.00 33.76  ? 723 HOH B O   1 
HETATM 21684 O O   . HOH P 5 .   ? 11.569  63.456  34.724  1.00 34.11  ? 724 HOH B O   1 
HETATM 21685 O O   . HOH P 5 .   ? -13.029 43.436  27.993  1.00 35.39  ? 725 HOH B O   1 
HETATM 21686 O O   . HOH P 5 .   ? -23.292 57.109  3.236   1.00 31.87  ? 726 HOH B O   1 
HETATM 21687 O O   . HOH P 5 .   ? -24.516 50.588  43.915  1.00 48.64  ? 727 HOH B O   1 
HETATM 21688 O O   . HOH P 5 .   ? -3.389  26.257  32.758  1.00 26.87  ? 728 HOH B O   1 
HETATM 21689 O O   . HOH P 5 .   ? -38.907 67.576  6.148   1.00 33.60  ? 729 HOH B O   1 
HETATM 21690 O O   . HOH P 5 .   ? -22.718 38.841  33.423  1.00 30.70  ? 730 HOH B O   1 
HETATM 21691 O O   . HOH P 5 .   ? -14.753 70.681  37.904  1.00 33.84  ? 731 HOH B O   1 
HETATM 21692 O O   . HOH P 5 .   ? -25.467 61.189  43.786  1.00 31.07  ? 732 HOH B O   1 
HETATM 21693 O O   . HOH P 5 .   ? -2.415  21.969  47.732  1.00 41.51  ? 733 HOH B O   1 
HETATM 21694 O O   . HOH P 5 .   ? -13.010 71.709  29.756  1.00 24.80  ? 734 HOH B O   1 
HETATM 21695 O O   . HOH P 5 .   ? -14.712 36.311  33.071  1.00 21.09  ? 735 HOH B O   1 
HETATM 21696 O O   . HOH P 5 .   ? 9.602   39.061  33.770  1.00 34.10  ? 736 HOH B O   1 
HETATM 21697 O O   . HOH P 5 .   ? 1.281   63.672  30.602  1.00 25.43  ? 737 HOH B O   1 
HETATM 21698 O O   . HOH P 5 .   ? 9.998   37.761  35.992  1.00 33.21  ? 738 HOH B O   1 
HETATM 21699 O O   . HOH P 5 .   ? -34.011 49.132  33.422  1.00 31.14  ? 739 HOH B O   1 
HETATM 21700 O O   . HOH P 5 .   ? -15.783 72.840  13.919  1.00 42.93  ? 740 HOH B O   1 
HETATM 21701 O O   . HOH P 5 .   ? -10.889 21.001  36.251  1.00 35.14  ? 741 HOH B O   1 
HETATM 21702 O O   . HOH P 5 .   ? 3.085   50.725  39.526  1.00 36.06  ? 742 HOH B O   1 
HETATM 21703 O O   . HOH P 5 .   ? -40.010 51.112  16.889  1.00 32.87  ? 743 HOH B O   1 
HETATM 21704 O O   . HOH P 5 .   ? -16.495 66.801  5.901   1.00 30.82  ? 744 HOH B O   1 
HETATM 21705 O O   . HOH P 5 .   ? 3.348   61.105  37.419  1.00 47.09  ? 745 HOH B O   1 
HETATM 21706 O O   . HOH P 5 .   ? -32.003 48.874  29.287  1.00 26.68  ? 746 HOH B O   1 
HETATM 21707 O O   . HOH P 5 .   ? -21.617 58.906  1.864   1.00 37.18  ? 747 HOH B O   1 
HETATM 21708 O O   . HOH P 5 .   ? -39.122 47.815  18.578  1.00 39.77  ? 748 HOH B O   1 
HETATM 21709 O O   . HOH P 5 .   ? -19.120 70.059  11.269  1.00 41.45  ? 749 HOH B O   1 
HETATM 21710 O O   . HOH P 5 .   ? -31.849 50.977  27.825  1.00 39.71  ? 750 HOH B O   1 
HETATM 21711 O O   . HOH P 5 .   ? -19.311 59.306  3.209   1.00 48.27  ? 751 HOH B O   1 
HETATM 21712 O O   . HOH P 5 .   ? -21.609 61.614  0.781   1.00 33.51  ? 752 HOH B O   1 
HETATM 21713 O O   . HOH Q 5 .   ? 16.637  67.836  32.834  1.00 33.99  ? 501 HOH C O   1 
HETATM 21714 O O   . HOH Q 5 .   ? 23.209  53.965  29.046  1.00 21.86  ? 502 HOH C O   1 
HETATM 21715 O O   . HOH Q 5 .   ? 73.653  46.452  44.153  1.00 40.88  ? 503 HOH C O   1 
HETATM 21716 O O   . HOH Q 5 .   ? 16.631  73.664  60.512  1.00 29.73  ? 504 HOH C O   1 
HETATM 21717 O O   . HOH Q 5 .   ? 23.711  58.415  78.697  1.00 36.74  ? 505 HOH C O   1 
HETATM 21718 O O   . HOH Q 5 .   ? 35.773  59.187  58.518  1.00 30.37  ? 506 HOH C O   1 
HETATM 21719 O O   . HOH Q 5 .   ? 19.306  63.809  60.389  1.00 17.94  ? 507 HOH C O   1 
HETATM 21720 O O   . HOH Q 5 .   ? 27.273  48.683  60.284  1.00 34.91  ? 508 HOH C O   1 
HETATM 21721 O O   . HOH Q 5 .   ? 30.155  72.328  45.614  1.00 19.34  ? 509 HOH C O   1 
HETATM 21722 O O   . HOH Q 5 .   ? 24.730  62.382  78.524  1.00 32.01  ? 510 HOH C O   1 
HETATM 21723 O O   . HOH Q 5 .   ? 21.319  59.518  30.785  1.00 28.98  ? 511 HOH C O   1 
HETATM 21724 O O   . HOH Q 5 .   ? 15.609  62.396  66.911  1.00 19.91  ? 512 HOH C O   1 
HETATM 21725 O O   . HOH Q 5 .   ? 47.177  80.775  62.580  1.00 33.97  ? 513 HOH C O   1 
HETATM 21726 O O   . HOH Q 5 .   ? 44.822  65.339  53.134  1.00 19.35  ? 514 HOH C O   1 
HETATM 21727 O O   . HOH Q 5 .   ? 59.295  56.771  71.228  1.00 31.32  ? 515 HOH C O   1 
HETATM 21728 O O   . HOH Q 5 .   ? 43.366  76.279  55.081  1.00 28.56  ? 516 HOH C O   1 
HETATM 21729 O O   . HOH Q 5 .   ? 44.074  57.862  67.428  1.00 24.81  ? 517 HOH C O   1 
HETATM 21730 O O   . HOH Q 5 .   ? 54.655  42.310  57.169  1.00 33.59  ? 518 HOH C O   1 
HETATM 21731 O O   . HOH Q 5 .   ? 36.798  57.057  59.625  1.00 19.09  ? 519 HOH C O   1 
HETATM 21732 O O   . HOH Q 5 .   ? 23.581  65.934  30.599  1.00 26.72  ? 520 HOH C O   1 
HETATM 21733 O O   . HOH Q 5 .   ? 16.608  69.498  65.731  1.00 22.38  ? 521 HOH C O   1 
HETATM 21734 O O   . HOH Q 5 .   ? 31.776  54.840  63.306  1.00 30.03  ? 522 HOH C O   1 
HETATM 21735 O O   . HOH Q 5 .   ? 10.601  38.423  63.140  1.00 41.09  ? 523 HOH C O   1 
HETATM 21736 O O   . HOH Q 5 .   ? 33.531  80.645  51.614  1.00 37.14  ? 524 HOH C O   1 
HETATM 21737 O O   . HOH Q 5 .   ? 68.668  48.338  45.337  1.00 26.29  ? 525 HOH C O   1 
HETATM 21738 O O   . HOH Q 5 .   ? 16.188  33.172  56.804  1.00 34.42  ? 526 HOH C O   1 
HETATM 21739 O O   . HOH Q 5 .   ? 30.560  76.517  69.726  1.00 27.73  ? 527 HOH C O   1 
HETATM 21740 O O   . HOH Q 5 .   ? 13.433  59.603  45.728  1.00 27.92  ? 528 HOH C O   1 
HETATM 21741 O O   . HOH Q 5 .   ? 14.910  51.207  36.762  1.00 21.33  ? 529 HOH C O   1 
HETATM 21742 O O   . HOH Q 5 .   ? 39.134  66.848  49.278  1.00 21.84  ? 530 HOH C O   1 
HETATM 21743 O O   . HOH Q 5 .   ? 17.938  75.252  43.237  1.00 46.76  ? 531 HOH C O   1 
HETATM 21744 O O   . HOH Q 5 .   ? 26.798  49.160  57.164  1.00 46.52  ? 532 HOH C O   1 
HETATM 21745 O O   . HOH Q 5 .   ? 50.037  74.637  60.247  1.00 31.78  ? 533 HOH C O   1 
HETATM 21746 O O   . HOH Q 5 .   ? 54.957  65.520  52.325  1.00 34.17  ? 534 HOH C O   1 
HETATM 21747 O O   . HOH Q 5 .   ? 38.075  61.036  76.583  1.00 37.55  ? 535 HOH C O   1 
HETATM 21748 O O   . HOH Q 5 .   ? 10.262  34.786  68.238  1.00 48.39  ? 536 HOH C O   1 
HETATM 21749 O O   . HOH Q 5 .   ? 17.034  67.954  71.503  1.00 31.59  ? 537 HOH C O   1 
HETATM 21750 O O   . HOH Q 5 .   ? 15.040  59.477  43.480  1.00 26.52  ? 538 HOH C O   1 
HETATM 21751 O O   . HOH Q 5 .   ? 36.574  68.031  72.128  1.00 28.45  ? 539 HOH C O   1 
HETATM 21752 O O   . HOH Q 5 .   ? 39.608  82.614  60.083  1.00 33.28  ? 540 HOH C O   1 
HETATM 21753 O O   . HOH Q 5 .   ? 17.100  67.779  54.961  1.00 32.99  ? 541 HOH C O   1 
HETATM 21754 O O   . HOH Q 5 .   ? 17.778  65.706  31.597  1.00 33.60  ? 542 HOH C O   1 
HETATM 21755 O O   . HOH Q 5 .   ? 34.945  69.863  36.123  1.00 24.72  ? 543 HOH C O   1 
HETATM 21756 O O   . HOH Q 5 .   ? 50.372  77.865  58.760  1.00 44.97  ? 544 HOH C O   1 
HETATM 21757 O O   . HOH Q 5 .   ? 39.064  61.330  55.721  1.00 23.17  ? 545 HOH C O   1 
HETATM 21758 O O   . HOH Q 5 .   ? 43.201  59.587  65.547  1.00 29.80  ? 546 HOH C O   1 
HETATM 21759 O O   . HOH Q 5 .   ? 13.048  56.720  69.022  1.00 29.81  ? 547 HOH C O   1 
HETATM 21760 O O   . HOH Q 5 .   ? 13.265  67.227  61.542  1.00 24.89  ? 548 HOH C O   1 
HETATM 21761 O O   . HOH Q 5 .   ? 32.913  78.651  53.739  1.00 33.73  ? 549 HOH C O   1 
HETATM 21762 O O   . HOH Q 5 .   ? 29.761  76.014  42.604  1.00 40.16  ? 550 HOH C O   1 
HETATM 21763 O O   . HOH Q 5 .   ? 32.650  52.570  43.600  1.00 27.50  ? 551 HOH C O   1 
HETATM 21764 O O   . HOH Q 5 .   ? 18.046  62.168  33.156  1.00 38.87  ? 552 HOH C O   1 
HETATM 21765 O O   . HOH Q 5 .   ? 23.999  70.029  46.665  1.00 26.34  ? 553 HOH C O   1 
HETATM 21766 O O   . HOH Q 5 .   ? 41.069  69.970  65.549  1.00 33.29  ? 554 HOH C O   1 
HETATM 21767 O O   . HOH Q 5 .   ? 45.575  73.572  52.875  1.00 32.42  ? 555 HOH C O   1 
HETATM 21768 O O   . HOH Q 5 .   ? 15.147  55.445  70.531  1.00 38.29  ? 556 HOH C O   1 
HETATM 21769 O O   . HOH Q 5 .   ? 73.972  41.766  50.807  1.00 37.87  ? 557 HOH C O   1 
HETATM 21770 O O   . HOH Q 5 .   ? 48.723  69.380  50.946  1.00 29.85  ? 558 HOH C O   1 
HETATM 21771 O O   . HOH Q 5 .   ? 21.147  77.786  58.311  1.00 38.33  ? 559 HOH C O   1 
HETATM 21772 O O   . HOH Q 5 .   ? 8.294   64.517  48.810  1.00 37.08  ? 560 HOH C O   1 
HETATM 21773 O O   . HOH Q 5 .   ? 40.162  69.356  42.432  1.00 26.76  ? 561 HOH C O   1 
HETATM 21774 O O   . HOH Q 5 .   ? 52.009  45.809  52.562  1.00 34.47  ? 562 HOH C O   1 
HETATM 21775 O O   . HOH Q 5 .   ? 51.005  71.991  53.045  1.00 36.02  ? 563 HOH C O   1 
HETATM 21776 O O   . HOH Q 5 .   ? 27.072  75.581  41.156  1.00 27.83  ? 564 HOH C O   1 
HETATM 21777 O O   . HOH Q 5 .   ? 27.952  51.784  35.031  1.00 20.27  ? 565 HOH C O   1 
HETATM 21778 O O   . HOH Q 5 .   ? 16.790  61.435  44.012  1.00 21.16  ? 566 HOH C O   1 
HETATM 21779 O O   . HOH Q 5 .   ? 24.302  74.923  46.800  1.00 37.39  ? 567 HOH C O   1 
HETATM 21780 O O   . HOH Q 5 .   ? 21.706  45.054  43.865  1.00 29.39  ? 568 HOH C O   1 
HETATM 21781 O O   . HOH Q 5 .   ? 56.933  52.697  70.408  1.00 42.38  ? 569 HOH C O   1 
HETATM 21782 O O   . HOH Q 5 .   ? 26.106  40.685  50.820  1.00 37.72  ? 570 HOH C O   1 
HETATM 21783 O O   . HOH Q 5 .   ? 58.937  60.023  50.345  1.00 30.83  ? 571 HOH C O   1 
HETATM 21784 O O   . HOH Q 5 .   ? 21.381  54.998  38.261  1.00 30.13  ? 572 HOH C O   1 
HETATM 21785 O O   . HOH Q 5 .   ? 44.984  56.646  70.459  1.00 32.72  ? 573 HOH C O   1 
HETATM 21786 O O   . HOH Q 5 .   ? 36.363  70.381  47.948  1.00 23.64  ? 574 HOH C O   1 
HETATM 21787 O O   . HOH Q 5 .   ? 56.350  74.351  61.485  1.00 29.19  ? 575 HOH C O   1 
HETATM 21788 O O   . HOH Q 5 .   ? 15.239  41.943  61.242  1.00 37.87  ? 576 HOH C O   1 
HETATM 21789 O O   . HOH Q 5 .   ? 20.178  49.169  77.018  1.00 34.40  ? 577 HOH C O   1 
HETATM 21790 O O   . HOH Q 5 .   ? 41.537  63.102  70.824  1.00 38.85  ? 578 HOH C O   1 
HETATM 21791 O O   . HOH Q 5 .   ? 20.564  43.144  34.048  1.00 32.51  ? 579 HOH C O   1 
HETATM 21792 O O   . HOH Q 5 .   ? 48.448  62.044  55.121  1.00 35.46  ? 580 HOH C O   1 
HETATM 21793 O O   . HOH Q 5 .   ? 54.441  59.091  64.470  1.00 30.25  ? 581 HOH C O   1 
HETATM 21794 O O   . HOH Q 5 .   ? 28.046  44.305  47.537  1.00 41.13  ? 582 HOH C O   1 
HETATM 21795 O O   . HOH Q 5 .   ? 20.137  80.844  63.512  1.00 30.65  ? 583 HOH C O   1 
HETATM 21796 O O   . HOH Q 5 .   ? 50.437  61.813  56.954  1.00 29.66  ? 584 HOH C O   1 
HETATM 21797 O O   . HOH Q 5 .   ? 35.932  50.536  67.662  1.00 41.11  ? 585 HOH C O   1 
HETATM 21798 O O   . HOH Q 5 .   ? 54.472  56.111  70.457  1.00 30.55  ? 586 HOH C O   1 
HETATM 21799 O O   . HOH Q 5 .   ? 64.088  50.279  47.354  1.00 32.83  ? 587 HOH C O   1 
HETATM 21800 O O   . HOH Q 5 .   ? 16.641  75.755  54.481  1.00 44.15  ? 588 HOH C O   1 
HETATM 21801 O O   . HOH Q 5 .   ? 42.172  63.671  59.944  1.00 36.21  ? 589 HOH C O   1 
HETATM 21802 O O   . HOH Q 5 .   ? 12.274  68.183  63.762  1.00 28.52  ? 590 HOH C O   1 
HETATM 21803 O O   . HOH Q 5 .   ? 6.665   60.319  60.499  1.00 32.96  ? 591 HOH C O   1 
HETATM 21804 O O   . HOH Q 5 .   ? 15.379  52.999  35.108  1.00 22.92  ? 592 HOH C O   1 
HETATM 21805 O O   . HOH Q 5 .   ? 52.663  69.618  50.086  1.00 24.59  ? 593 HOH C O   1 
HETATM 21806 O O   . HOH Q 5 .   ? 28.694  82.032  57.927  1.00 41.83  ? 594 HOH C O   1 
HETATM 21807 O O   . HOH Q 5 .   ? 39.857  49.605  56.106  1.00 41.99  ? 595 HOH C O   1 
HETATM 21808 O O   . HOH Q 5 .   ? 31.713  71.044  74.361  1.00 29.96  ? 596 HOH C O   1 
HETATM 21809 O O   . HOH Q 5 .   ? 25.215  39.771  65.813  1.00 42.13  ? 597 HOH C O   1 
HETATM 21810 O O   . HOH Q 5 .   ? 34.214  44.309  54.433  1.00 33.66  ? 598 HOH C O   1 
HETATM 21811 O O   . HOH Q 5 .   ? 9.130   59.466  39.062  1.00 31.18  ? 599 HOH C O   1 
HETATM 21812 O O   . HOH Q 5 .   ? 25.904  76.197  63.110  1.00 34.45  ? 600 HOH C O   1 
HETATM 21813 O O   . HOH Q 5 .   ? 58.966  50.859  68.247  1.00 33.29  ? 601 HOH C O   1 
HETATM 21814 O O   . HOH Q 5 .   ? 19.601  50.508  32.152  1.00 11.64  ? 602 HOH C O   1 
HETATM 21815 O O   . HOH Q 5 .   ? 41.372  71.414  42.910  1.00 25.69  ? 603 HOH C O   1 
HETATM 21816 O O   . HOH Q 5 .   ? 21.867  38.677  75.502  1.00 39.81  ? 604 HOH C O   1 
HETATM 21817 O O   . HOH Q 5 .   ? 20.804  53.091  30.788  1.00 25.30  ? 605 HOH C O   1 
HETATM 21818 O O   . HOH Q 5 .   ? 50.671  71.271  50.416  1.00 23.01  ? 606 HOH C O   1 
HETATM 21819 O O   . HOH Q 5 .   ? 26.152  79.558  55.266  1.00 44.95  ? 607 HOH C O   1 
HETATM 21820 O O   . HOH Q 5 .   ? 8.497   51.430  69.652  1.00 32.00  ? 608 HOH C O   1 
HETATM 21821 O O   . HOH Q 5 .   ? 32.005  46.436  56.817  1.00 40.36  ? 609 HOH C O   1 
HETATM 21822 O O   . HOH Q 5 .   ? 31.329  68.928  78.269  1.00 49.68  ? 610 HOH C O   1 
HETATM 21823 O O   . HOH Q 5 .   ? 71.419  41.074  53.468  1.00 38.68  ? 611 HOH C O   1 
HETATM 21824 O O   . HOH Q 5 .   ? 58.210  56.465  46.763  1.00 30.30  ? 612 HOH C O   1 
HETATM 21825 O O   . HOH Q 5 .   ? 42.809  65.478  69.226  1.00 31.97  ? 613 HOH C O   1 
HETATM 21826 O O   . HOH Q 5 .   ? 28.222  79.027  66.797  1.00 26.05  ? 614 HOH C O   1 
HETATM 21827 O O   . HOH Q 5 .   ? 28.082  76.975  46.535  1.00 29.35  ? 615 HOH C O   1 
HETATM 21828 O O   . HOH Q 5 .   ? 62.617  52.702  70.659  1.00 32.79  ? 616 HOH C O   1 
HETATM 21829 O O   . HOH Q 5 .   ? 49.068  64.694  55.153  1.00 25.90  ? 617 HOH C O   1 
HETATM 21830 O O   . HOH Q 5 .   ? 71.373  36.697  60.722  1.00 41.07  ? 618 HOH C O   1 
HETATM 21831 O O   . HOH Q 5 .   ? 52.563  73.843  56.632  1.00 30.58  ? 619 HOH C O   1 
HETATM 21832 O O   . HOH Q 5 .   ? 12.645  44.809  75.689  1.00 37.18  ? 620 HOH C O   1 
HETATM 21833 O O   . HOH Q 5 .   ? 14.967  63.445  45.134  1.00 29.37  ? 621 HOH C O   1 
HETATM 21834 O O   . HOH Q 5 .   ? 12.982  74.148  45.435  1.00 35.71  ? 622 HOH C O   1 
HETATM 21835 O O   . HOH Q 5 .   ? 11.950  71.563  60.380  1.00 38.54  ? 623 HOH C O   1 
HETATM 21836 O O   . HOH Q 5 .   ? 37.359  36.186  66.347  1.00 47.46  ? 624 HOH C O   1 
HETATM 21837 O O   . HOH Q 5 .   ? 32.855  42.286  60.945  1.00 39.88  ? 625 HOH C O   1 
HETATM 21838 O O   . HOH Q 5 .   ? 6.789   54.465  63.777  1.00 49.99  ? 626 HOH C O   1 
HETATM 21839 O O   . HOH Q 5 .   ? 21.575  76.551  43.122  1.00 41.43  ? 627 HOH C O   1 
HETATM 21840 O O   . HOH Q 5 .   ? 10.275  62.388  63.250  1.00 28.13  ? 628 HOH C O   1 
HETATM 21841 O O   . HOH Q 5 .   ? 9.644   69.638  63.622  1.00 34.91  ? 629 HOH C O   1 
HETATM 21842 O O   . HOH Q 5 .   ? 16.410  53.127  32.198  1.00 34.52  ? 630 HOH C O   1 
HETATM 21843 O O   . HOH Q 5 .   ? 43.973  84.720  55.126  1.00 42.36  ? 631 HOH C O   1 
HETATM 21844 O O   . HOH Q 5 .   ? 10.276  66.636  61.197  1.00 33.61  ? 632 HOH C O   1 
HETATM 21845 O O   . HOH Q 5 .   ? 30.564  68.913  82.654  1.00 39.72  ? 633 HOH C O   1 
HETATM 21846 O O   . HOH Q 5 .   ? 19.976  42.249  36.583  1.00 27.82  ? 634 HOH C O   1 
HETATM 21847 O O   . HOH Q 5 .   ? 18.656  78.732  59.525  1.00 41.37  ? 635 HOH C O   1 
HETATM 21848 O O   . HOH Q 5 .   ? 8.164   61.542  62.351  1.00 33.88  ? 636 HOH C O   1 
HETATM 21849 O O   . HOH R 5 .   ? 9.836   59.891  -1.802  1.00 22.09  ? 601 HOH D O   1 
HETATM 21850 O O   . HOH R 5 .   ? 3.198   64.277  14.530  1.00 32.16  ? 602 HOH D O   1 
HETATM 21851 O O   . HOH R 5 .   ? 24.478  96.463  -11.962 1.00 36.86  ? 603 HOH D O   1 
HETATM 21852 O O   . HOH R 5 .   ? 38.504  64.437  -0.092  1.00 42.84  ? 604 HOH D O   1 
HETATM 21853 O O   . HOH R 5 .   ? 21.619  104.636 -11.498 1.00 33.82  ? 605 HOH D O   1 
HETATM 21854 O O   . HOH R 5 .   ? 35.943  79.581  -21.873 1.00 25.88  ? 606 HOH D O   1 
HETATM 21855 O O   . HOH R 5 .   ? 33.686  76.152  10.820  1.00 19.45  ? 607 HOH D O   1 
HETATM 21856 O O   . HOH R 5 .   ? 29.326  85.011  14.950  1.00 22.58  ? 608 HOH D O   1 
HETATM 21857 O O   . HOH R 5 .   ? 6.874   67.253  5.194   1.00 27.66  ? 609 HOH D O   1 
HETATM 21858 O O   . HOH R 5 .   ? 27.707  91.814  5.014   1.00 26.71  ? 610 HOH D O   1 
HETATM 21859 O O   . HOH R 5 .   ? 14.162  114.033 -8.829  1.00 39.04  ? 611 HOH D O   1 
HETATM 21860 O O   . HOH R 5 .   ? 36.282  70.425  8.458   1.00 30.61  ? 612 HOH D O   1 
HETATM 21861 O O   . HOH R 5 .   ? 34.119  79.045  17.623  1.00 35.97  ? 613 HOH D O   1 
HETATM 21862 O O   . HOH R 5 .   ? 18.862  64.140  20.889  1.00 22.98  ? 614 HOH D O   1 
HETATM 21863 O O   . HOH R 5 .   ? 14.824  57.616  -8.878  1.00 30.76  ? 615 HOH D O   1 
HETATM 21864 O O   . HOH R 5 .   ? 19.204  81.041  -8.775  1.00 18.41  ? 616 HOH D O   1 
HETATM 21865 O O   . HOH R 5 .   ? 37.743  65.680  -6.291  1.00 36.67  ? 617 HOH D O   1 
HETATM 21866 O O   . HOH R 5 .   ? 27.189  88.636  -13.423 1.00 22.60  ? 618 HOH D O   1 
HETATM 21867 O O   . HOH R 5 .   ? 7.798   66.368  -24.365 1.00 43.38  ? 619 HOH D O   1 
HETATM 21868 O O   . HOH R 5 .   ? 34.343  93.743  19.822  1.00 19.18  ? 620 HOH D O   1 
HETATM 21869 O O   . HOH R 5 .   ? 33.665  68.586  13.596  1.00 35.47  ? 621 HOH D O   1 
HETATM 21870 O O   . HOH R 5 .   ? 21.860  59.449  4.901   1.00 16.28  ? 622 HOH D O   1 
HETATM 21871 O O   . HOH R 5 .   ? 24.573  92.238  -8.498  1.00 22.50  ? 623 HOH D O   1 
HETATM 21872 O O   . HOH R 5 .   ? 6.699   110.269 13.808  1.00 38.91  ? 624 HOH D O   1 
HETATM 21873 O O   . HOH R 5 .   ? 22.832  103.164 -5.480  1.00 35.02  ? 625 HOH D O   1 
HETATM 21874 O O   . HOH R 5 .   ? 37.581  98.359  0.768   1.00 27.17  ? 626 HOH D O   1 
HETATM 21875 O O   . HOH R 5 .   ? 20.706  75.753  -20.976 1.00 31.07  ? 627 HOH D O   1 
HETATM 21876 O O   . HOH R 5 .   ? 35.900  74.700  13.905  1.00 35.23  ? 628 HOH D O   1 
HETATM 21877 O O   . HOH R 5 .   ? 41.118  95.658  11.233  1.00 25.86  ? 629 HOH D O   1 
HETATM 21878 O O   . HOH R 5 .   ? 12.574  75.809  -7.844  1.00 22.33  ? 630 HOH D O   1 
HETATM 21879 O O   . HOH R 5 .   ? 21.512  66.347  -18.789 1.00 27.05  ? 631 HOH D O   1 
HETATM 21880 O O   . HOH R 5 .   ? -7.493  91.783  -15.174 1.00 27.90  ? 632 HOH D O   1 
HETATM 21881 O O   . HOH R 5 .   ? 21.312  85.343  -4.237  1.00 16.82  ? 633 HOH D O   1 
HETATM 21882 O O   . HOH R 5 .   ? 38.565  90.938  16.198  1.00 27.08  ? 634 HOH D O   1 
HETATM 21883 O O   . HOH R 5 .   ? 12.506  63.806  19.225  1.00 33.02  ? 635 HOH D O   1 
HETATM 21884 O O   . HOH R 5 .   ? 35.518  101.294 5.331   1.00 29.64  ? 636 HOH D O   1 
HETATM 21885 O O   . HOH R 5 .   ? 5.260   75.806  -17.472 1.00 31.37  ? 637 HOH D O   1 
HETATM 21886 O O   . HOH R 5 .   ? 27.215  96.377  4.080   1.00 22.42  ? 638 HOH D O   1 
HETATM 21887 O O   . HOH R 5 .   ? 10.439  84.643  -15.718 1.00 30.29  ? 639 HOH D O   1 
HETATM 21888 O O   . HOH R 5 .   ? 41.564  81.004  -11.877 1.00 20.58  ? 640 HOH D O   1 
HETATM 21889 O O   . HOH R 5 .   ? 21.888  55.582  -1.620  1.00 21.83  ? 641 HOH D O   1 
HETATM 21890 O O   . HOH R 5 .   ? 35.388  73.345  18.688  1.00 38.75  ? 642 HOH D O   1 
HETATM 21891 O O   . HOH R 5 .   ? 28.062  68.327  -7.468  1.00 18.50  ? 643 HOH D O   1 
HETATM 21892 O O   . HOH R 5 .   ? 24.523  61.137  20.856  1.00 25.51  ? 644 HOH D O   1 
HETATM 21893 O O   . HOH R 5 .   ? 38.038  92.192  13.655  1.00 25.73  ? 645 HOH D O   1 
HETATM 21894 O O   . HOH R 5 .   ? 13.893  59.160  -16.738 1.00 34.43  ? 646 HOH D O   1 
HETATM 21895 O O   . HOH R 5 .   ? 6.585   69.762  7.236   1.00 28.06  ? 647 HOH D O   1 
HETATM 21896 O O   . HOH R 5 .   ? -1.085  75.307  -6.026  1.00 36.66  ? 648 HOH D O   1 
HETATM 21897 O O   . HOH R 5 .   ? 6.487   64.386  -13.280 1.00 32.89  ? 649 HOH D O   1 
HETATM 21898 O O   . HOH R 5 .   ? 7.595   73.077  12.319  1.00 26.12  ? 650 HOH D O   1 
HETATM 21899 O O   . HOH R 5 .   ? 7.600   59.915  1.822   1.00 34.32  ? 651 HOH D O   1 
HETATM 21900 O O   . HOH R 5 .   ? 30.526  95.194  8.586   1.00 34.14  ? 652 HOH D O   1 
HETATM 21901 O O   . HOH R 5 .   ? 19.797  97.004  9.218   1.00 14.83  ? 653 HOH D O   1 
HETATM 21902 O O   . HOH R 5 .   ? 2.821   72.090  -0.402  1.00 35.75  ? 654 HOH D O   1 
HETATM 21903 O O   . HOH R 5 .   ? 3.779   60.383  -17.207 1.00 29.16  ? 655 HOH D O   1 
HETATM 21904 O O   . HOH R 5 .   ? 45.797  87.946  0.524   1.00 40.36  ? 656 HOH D O   1 
HETATM 21905 O O   . HOH R 5 .   ? 27.164  86.909  -21.682 1.00 37.16  ? 657 HOH D O   1 
HETATM 21906 O O   . HOH R 5 .   ? 9.545   60.601  -20.936 1.00 38.04  ? 658 HOH D O   1 
HETATM 21907 O O   . HOH R 5 .   ? 7.127   72.045  -12.105 1.00 21.23  ? 659 HOH D O   1 
HETATM 21908 O O   . HOH R 5 .   ? 26.670  90.605  -2.230  1.00 13.29  ? 660 HOH D O   1 
HETATM 21909 O O   . HOH R 5 .   ? 34.000  97.853  7.449   1.00 24.64  ? 661 HOH D O   1 
HETATM 21910 O O   . HOH R 5 .   ? 38.648  90.589  4.814   1.00 20.57  ? 662 HOH D O   1 
HETATM 21911 O O   . HOH R 5 .   ? 17.583  85.423  -22.088 1.00 35.28  ? 663 HOH D O   1 
HETATM 21912 O O   . HOH R 5 .   ? 31.327  86.516  15.061  1.00 21.86  ? 664 HOH D O   1 
HETATM 21913 O O   . HOH R 5 .   ? 7.432   73.154  -9.733  1.00 22.69  ? 665 HOH D O   1 
HETATM 21914 O O   . HOH R 5 .   ? 9.750   112.877 12.539  1.00 44.27  ? 666 HOH D O   1 
HETATM 21915 O O   . HOH R 5 .   ? 31.004  64.806  -1.895  1.00 30.11  ? 667 HOH D O   1 
HETATM 21916 O O   . HOH R 5 .   ? 15.845  100.482 -10.225 1.00 39.35  ? 668 HOH D O   1 
HETATM 21917 O O   . HOH R 5 .   ? 42.820  84.976  11.561  1.00 41.57  ? 669 HOH D O   1 
HETATM 21918 O O   . HOH R 5 .   ? 35.327  92.890  6.923   1.00 25.66  ? 670 HOH D O   1 
HETATM 21919 O O   . HOH R 5 .   ? 17.321  84.384  -14.035 1.00 37.18  ? 671 HOH D O   1 
HETATM 21920 O O   . HOH R 5 .   ? 31.474  69.990  7.960   1.00 26.90  ? 672 HOH D O   1 
HETATM 21921 O O   . HOH R 5 .   ? -15.996 71.119  -13.366 1.00 43.30  ? 673 HOH D O   1 
HETATM 21922 O O   . HOH R 5 .   ? 27.968  66.282  -14.799 1.00 24.66  ? 674 HOH D O   1 
HETATM 21923 O O   . HOH R 5 .   ? 2.250   69.198  -23.841 1.00 33.66  ? 675 HOH D O   1 
HETATM 21924 O O   . HOH R 5 .   ? 31.815  72.944  -12.782 1.00 21.71  ? 676 HOH D O   1 
HETATM 21925 O O   . HOH R 5 .   ? 8.930   55.734  4.224   1.00 32.01  ? 677 HOH D O   1 
HETATM 21926 O O   . HOH R 5 .   ? 15.356  65.829  12.702  1.00 25.12  ? 678 HOH D O   1 
HETATM 21927 O O   . HOH R 5 .   ? 21.944  52.585  5.983   1.00 33.55  ? 679 HOH D O   1 
HETATM 21928 O O   . HOH R 5 .   ? 23.000  62.452  7.556   1.00 25.49  ? 680 HOH D O   1 
HETATM 21929 O O   . HOH R 5 .   ? 0.376   63.847  -3.705  1.00 41.84  ? 681 HOH D O   1 
HETATM 21930 O O   . HOH R 5 .   ? 13.370  59.424  14.504  1.00 22.18  ? 682 HOH D O   1 
HETATM 21931 O O   . HOH R 5 .   ? 2.748   76.718  -13.573 1.00 27.50  ? 683 HOH D O   1 
HETATM 21932 O O   . HOH R 5 .   ? 8.041   98.258  2.797   1.00 32.16  ? 684 HOH D O   1 
HETATM 21933 O O   . HOH R 5 .   ? 33.597  68.169  -18.165 1.00 35.61  ? 685 HOH D O   1 
HETATM 21934 O O   . HOH R 5 .   ? 11.158  85.533  -3.446  1.00 34.10  ? 686 HOH D O   1 
HETATM 21935 O O   . HOH R 5 .   ? 12.684  74.429  -5.271  1.00 26.00  ? 687 HOH D O   1 
HETATM 21936 O O   . HOH R 5 .   ? 21.420  82.929  -17.865 1.00 29.95  ? 688 HOH D O   1 
HETATM 21937 O O   . HOH R 5 .   ? 28.531  85.578  7.896   1.00 23.58  ? 689 HOH D O   1 
HETATM 21938 O O   . HOH R 5 .   ? 29.978  64.182  9.852   1.00 40.15  ? 690 HOH D O   1 
HETATM 21939 O O   . HOH R 5 .   ? 34.480  66.158  -16.311 1.00 37.06  ? 691 HOH D O   1 
HETATM 21940 O O   . HOH R 5 .   ? 32.438  70.329  -19.499 1.00 31.57  ? 692 HOH D O   1 
HETATM 21941 O O   . HOH R 5 .   ? 10.222  79.741  -4.592  1.00 34.98  ? 693 HOH D O   1 
HETATM 21942 O O   . HOH R 5 .   ? 6.054   67.532  2.548   1.00 32.06  ? 694 HOH D O   1 
HETATM 21943 O O   . HOH R 5 .   ? 44.634  73.598  -13.194 1.00 29.77  ? 695 HOH D O   1 
HETATM 21944 O O   . HOH R 5 .   ? 4.132   63.105  -1.275  1.00 33.06  ? 696 HOH D O   1 
HETATM 21945 O O   . HOH R 5 .   ? 27.401  55.019  1.456   1.00 29.32  ? 697 HOH D O   1 
HETATM 21946 O O   . HOH R 5 .   ? 31.942  82.711  9.076   1.00 23.42  ? 698 HOH D O   1 
HETATM 21947 O O   . HOH R 5 .   ? 10.813  98.687  2.870   1.00 34.07  ? 699 HOH D O   1 
HETATM 21948 O O   . HOH R 5 .   ? 12.944  80.746  -6.816  1.00 34.58  ? 700 HOH D O   1 
HETATM 21949 O O   . HOH R 5 .   ? 37.338  104.850 1.009   1.00 30.35  ? 701 HOH D O   1 
HETATM 21950 O O   . HOH R 5 .   ? 48.428  84.496  -3.834  1.00 38.26  ? 702 HOH D O   1 
HETATM 21951 O O   . HOH R 5 .   ? 25.540  95.789  -15.621 1.00 42.32  ? 703 HOH D O   1 
HETATM 21952 O O   . HOH R 5 .   ? 34.968  90.587  -6.755  1.00 35.98  ? 704 HOH D O   1 
HETATM 21953 O O   . HOH R 5 .   ? 7.238   86.883  -3.795  1.00 33.93  ? 705 HOH D O   1 
HETATM 21954 O O   . HOH R 5 .   ? 21.235  60.606  7.054   1.00 22.99  ? 706 HOH D O   1 
HETATM 21955 O O   . HOH R 5 .   ? 41.549  73.148  7.540   1.00 50.20  ? 707 HOH D O   1 
HETATM 21956 O O   . HOH R 5 .   ? 26.000  54.050  4.613   1.00 36.62  ? 708 HOH D O   1 
HETATM 21957 O O   . HOH R 5 .   ? 10.699  77.048  -4.785  1.00 28.61  ? 709 HOH D O   1 
HETATM 21958 O O   . HOH R 5 .   ? 30.454  98.676  10.291  1.00 34.07  ? 710 HOH D O   1 
HETATM 21959 O O   . HOH R 5 .   ? 13.249  77.778  9.300   1.00 15.84  ? 711 HOH D O   1 
HETATM 21960 O O   . HOH R 5 .   ? 0.441   63.632  -9.425  1.00 31.65  ? 712 HOH D O   1 
HETATM 21961 O O   . HOH R 5 .   ? -3.106  62.503  -21.208 1.00 29.97  ? 713 HOH D O   1 
HETATM 21962 O O   . HOH R 5 .   ? 11.804  58.813  12.321  1.00 32.47  ? 714 HOH D O   1 
HETATM 21963 O O   . HOH R 5 .   ? 11.248  74.995  -2.915  1.00 28.66  ? 715 HOH D O   1 
HETATM 21964 O O   . HOH R 5 .   ? 44.506  88.992  5.395   1.00 39.24  ? 716 HOH D O   1 
HETATM 21965 O O   . HOH R 5 .   ? 12.732  75.242  -25.131 1.00 42.66  ? 717 HOH D O   1 
HETATM 21966 O O   . HOH R 5 .   ? 4.578   75.212  -14.800 1.00 24.52  ? 718 HOH D O   1 
HETATM 21967 O O   . HOH R 5 .   ? 34.311  97.789  12.208  1.00 24.29  ? 719 HOH D O   1 
HETATM 21968 O O   . HOH R 5 .   ? 32.477  97.000  9.421   1.00 22.16  ? 720 HOH D O   1 
HETATM 21969 O O   . HOH R 5 .   ? 12.808  59.900  17.128  1.00 24.05  ? 721 HOH D O   1 
HETATM 21970 O O   . HOH R 5 .   ? -2.735  64.202  -9.824  1.00 40.48  ? 722 HOH D O   1 
HETATM 21971 O O   . HOH R 5 .   ? 38.263  83.197  -16.641 1.00 25.81  ? 723 HOH D O   1 
HETATM 21972 O O   . HOH R 5 .   ? 4.860   101.809 -2.079  1.00 33.53  ? 724 HOH D O   1 
HETATM 21973 O O   . HOH R 5 .   ? 38.950  91.340  -11.192 1.00 41.25  ? 725 HOH D O   1 
HETATM 21974 O O   . HOH R 5 .   ? 10.504  85.555  -23.123 1.00 36.30  ? 726 HOH D O   1 
HETATM 21975 O O   . HOH R 5 .   ? 25.970  95.018  0.050   1.00 21.80  ? 727 HOH D O   1 
HETATM 21976 O O   . HOH R 5 .   ? 20.743  53.752  10.128  1.00 26.46  ? 728 HOH D O   1 
HETATM 21977 O O   . HOH R 5 .   ? 24.542  98.188  1.637   1.00 39.84  ? 729 HOH D O   1 
HETATM 21978 O O   . HOH R 5 .   ? -8.601  68.723  -9.152  1.00 38.56  ? 730 HOH D O   1 
HETATM 21979 O O   . HOH R 5 .   ? 21.997  54.978  -13.160 1.00 24.12  ? 731 HOH D O   1 
HETATM 21980 O O   . HOH R 5 .   ? 28.885  89.703  -11.753 1.00 27.62  ? 732 HOH D O   1 
HETATM 21981 O O   . HOH R 5 .   ? 40.617  75.197  -6.525  1.00 32.81  ? 733 HOH D O   1 
HETATM 21982 O O   . HOH R 5 .   ? 7.711   81.394  -2.963  1.00 46.21  ? 734 HOH D O   1 
HETATM 21983 O O   . HOH R 5 .   ? 12.131  65.567  -26.781 1.00 29.99  ? 735 HOH D O   1 
HETATM 21984 O O   . HOH R 5 .   ? 45.368  72.204  -0.744  1.00 38.98  ? 736 HOH D O   1 
HETATM 21985 O O   . HOH R 5 .   ? 12.643  82.951  -4.939  1.00 44.41  ? 737 HOH D O   1 
HETATM 21986 O O   . HOH R 5 .   ? 24.407  86.787  0.401   1.00 27.03  ? 738 HOH D O   1 
HETATM 21987 O O   . HOH R 5 .   ? 32.241  62.707  -8.948  1.00 39.25  ? 739 HOH D O   1 
HETATM 21988 O O   . HOH R 5 .   ? 6.677   97.415  -4.186  1.00 35.15  ? 740 HOH D O   1 
HETATM 21989 O O   . HOH R 5 .   ? 40.581  79.696  4.549   1.00 34.64  ? 741 HOH D O   1 
HETATM 21990 O O   . HOH R 5 .   ? 8.882   74.365  2.544   1.00 33.58  ? 742 HOH D O   1 
HETATM 21991 O O   . HOH R 5 .   ? 5.773   61.636  -12.771 1.00 31.22  ? 743 HOH D O   1 
HETATM 21992 O O   . HOH R 5 .   ? 44.255  89.564  2.328   1.00 30.64  ? 744 HOH D O   1 
HETATM 21993 O O   . HOH R 5 .   ? 41.465  69.095  -2.370  1.00 30.56  ? 745 HOH D O   1 
HETATM 21994 O O   . HOH R 5 .   ? 5.896   64.144  -25.849 1.00 48.78  ? 746 HOH D O   1 
HETATM 21995 O O   . HOH R 5 .   ? 32.356  102.614 6.912   1.00 21.19  ? 747 HOH D O   1 
HETATM 21996 O O   . HOH R 5 .   ? 29.371  90.086  -3.522  1.00 29.52  ? 748 HOH D O   1 
HETATM 21997 O O   . HOH R 5 .   ? 32.531  86.846  18.278  1.00 28.43  ? 749 HOH D O   1 
HETATM 21998 O O   . HOH R 5 .   ? 30.680  82.316  19.551  1.00 27.18  ? 750 HOH D O   1 
HETATM 21999 O O   . HOH R 5 .   ? 10.011  62.967  17.588  1.00 3.98   ? 751 HOH D O   1 
HETATM 22000 O O   . HOH R 5 .   ? 29.195  90.238  -19.560 1.00 33.34  ? 752 HOH D O   1 
HETATM 22001 O O   . HOH R 5 .   ? 19.339  78.531  -20.386 1.00 33.66  ? 753 HOH D O   1 
HETATM 22002 O O   . HOH R 5 .   ? 2.944   82.030  -25.426 1.00 37.29  ? 754 HOH D O   1 
HETATM 22003 O O   . HOH R 5 .   ? 45.102  90.163  8.070   1.00 38.81  ? 755 HOH D O   1 
HETATM 22004 O O   . HOH R 5 .   ? 33.284  70.937  9.897   1.00 26.08  ? 756 HOH D O   1 
HETATM 22005 O O   . HOH R 5 .   ? 26.597  62.892  -20.942 1.00 38.97  ? 757 HOH D O   1 
HETATM 22006 O O   . HOH R 5 .   ? 7.368   63.577  8.348   1.00 31.46  ? 758 HOH D O   1 
HETATM 22007 O O   . HOH R 5 .   ? 41.172  68.147  0.273   1.00 34.52  ? 759 HOH D O   1 
HETATM 22008 O O   . HOH R 5 .   ? 33.905  63.532  -7.316  1.00 26.99  ? 760 HOH D O   1 
HETATM 22009 O O   . HOH R 5 .   ? 12.237  102.086 -8.400  1.00 30.08  ? 761 HOH D O   1 
HETATM 22010 O O   . HOH R 5 .   ? 44.646  81.052  -12.340 1.00 38.33  ? 762 HOH D O   1 
HETATM 22011 O O   . HOH R 5 .   ? 6.095   61.643  6.443   1.00 37.46  ? 763 HOH D O   1 
HETATM 22012 O O   . HOH R 5 .   ? 37.712  81.688  -21.412 1.00 38.00  ? 764 HOH D O   1 
HETATM 22013 O O   . HOH S 5 .   ? 35.725  46.119  42.863  1.00 27.95  ? 601 HOH E O   1 
HETATM 22014 O O   . HOH S 5 .   ? 56.681  61.318  36.933  1.00 31.20  ? 602 HOH E O   1 
HETATM 22015 O O   . HOH S 5 .   ? 46.233  48.926  19.374  1.00 34.90  ? 603 HOH E O   1 
HETATM 22016 O O   . HOH S 5 .   ? 60.236  36.217  29.685  1.00 28.46  ? 604 HOH E O   1 
HETATM 22017 O O   . HOH S 5 .   ? 32.165  42.428  30.053  1.00 32.17  ? 605 HOH E O   1 
HETATM 22018 O O   . HOH S 5 .   ? 38.259  50.252  14.607  1.00 32.37  ? 606 HOH E O   1 
HETATM 22019 O O   . HOH S 5 .   ? 44.905  71.430  19.076  1.00 24.51  ? 607 HOH E O   1 
HETATM 22020 O O   . HOH S 5 .   ? 37.312  43.973  32.618  1.00 24.11  ? 608 HOH E O   1 
HETATM 22021 O O   . HOH S 5 .   ? 50.005  68.230  32.988  1.00 38.23  ? 609 HOH E O   1 
HETATM 22022 O O   . HOH S 5 .   ? 55.942  65.196  31.795  1.00 21.89  ? 610 HOH E O   1 
HETATM 22023 O O   . HOH S 5 .   ? 38.474  59.596  18.019  1.00 30.47  ? 611 HOH E O   1 
HETATM 22024 O O   . HOH S 5 .   ? 45.845  75.882  23.960  1.00 32.40  ? 612 HOH E O   1 
HETATM 22025 O O   . HOH S 5 .   ? 59.915  45.768  15.965  1.00 37.68  ? 613 HOH E O   1 
HETATM 22026 O O   . HOH S 5 .   ? 50.621  64.675  57.386  1.00 24.65  ? 614 HOH E O   1 
HETATM 22027 O O   . HOH S 5 .   ? 23.700  55.381  23.295  1.00 29.52  ? 615 HOH E O   1 
HETATM 22028 O O   . HOH S 5 .   ? 62.120  46.315  17.320  1.00 31.41  ? 616 HOH E O   1 
HETATM 22029 O O   . HOH S 5 .   ? 48.146  38.205  21.610  1.00 28.03  ? 617 HOH E O   1 
HETATM 22030 O O   . HOH S 5 .   ? 37.757  39.620  29.517  1.00 31.07  ? 618 HOH E O   1 
HETATM 22031 O O   . HOH S 5 .   ? 51.070  58.885  48.230  1.00 24.69  ? 619 HOH E O   1 
HETATM 22032 O O   . HOH S 5 .   ? 59.984  83.161  36.922  1.00 40.24  ? 620 HOH E O   1 
HETATM 22033 O O   . HOH S 5 .   ? 68.268  73.411  18.564  1.00 31.63  ? 621 HOH E O   1 
HETATM 22034 O O   . HOH S 5 .   ? 52.246  81.459  29.685  1.00 31.79  ? 622 HOH E O   1 
HETATM 22035 O O   . HOH S 5 .   ? 71.013  49.701  40.238  1.00 22.21  ? 623 HOH E O   1 
HETATM 22036 O O   . HOH S 5 .   ? 55.884  67.237  59.888  1.00 30.34  ? 624 HOH E O   1 
HETATM 22037 O O   . HOH S 5 .   ? 50.131  51.564  42.119  1.00 23.57  ? 625 HOH E O   1 
HETATM 22038 O O   . HOH S 5 .   ? 43.362  60.574  12.816  1.00 21.99  ? 626 HOH E O   1 
HETATM 22039 O O   . HOH S 5 .   ? 74.044  52.025  35.654  1.00 45.21  ? 627 HOH E O   1 
HETATM 22040 O O   . HOH S 5 .   ? 72.651  55.393  35.266  1.00 30.65  ? 628 HOH E O   1 
HETATM 22041 O O   . HOH S 5 .   ? 47.333  44.773  49.002  1.00 35.39  ? 629 HOH E O   1 
HETATM 22042 O O   . HOH S 5 .   ? 46.452  66.716  75.448  1.00 37.24  ? 630 HOH E O   1 
HETATM 22043 O O   . HOH S 5 .   ? 36.143  59.423  20.171  1.00 32.13  ? 631 HOH E O   1 
HETATM 22044 O O   . HOH S 5 .   ? 56.811  70.958  30.110  1.00 29.60  ? 632 HOH E O   1 
HETATM 22045 O O   . HOH S 5 .   ? 65.036  72.907  30.105  1.00 32.74  ? 633 HOH E O   1 
HETATM 22046 O O   . HOH S 5 .   ? 31.345  68.995  21.909  1.00 21.20  ? 634 HOH E O   1 
HETATM 22047 O O   . HOH S 5 .   ? 36.040  43.474  43.988  1.00 26.22  ? 635 HOH E O   1 
HETATM 22048 O O   . HOH S 5 .   ? 66.086  48.737  40.944  1.00 26.10  ? 636 HOH E O   1 
HETATM 22049 O O   . HOH S 5 .   ? 52.341  48.866  53.189  1.00 29.23  ? 637 HOH E O   1 
HETATM 22050 O O   . HOH S 5 .   ? 61.942  75.301  32.809  1.00 22.35  ? 638 HOH E O   1 
HETATM 22051 O O   . HOH S 5 .   ? 54.394  55.498  39.818  1.00 32.76  ? 639 HOH E O   1 
HETATM 22052 O O   . HOH S 5 .   ? 62.105  52.382  45.800  1.00 39.48  ? 640 HOH E O   1 
HETATM 22053 O O   . HOH S 5 .   ? 52.469  70.268  74.212  1.00 34.51  ? 641 HOH E O   1 
HETATM 22054 O O   . HOH S 5 .   ? 38.389  47.308  26.610  1.00 22.73  ? 642 HOH E O   1 
HETATM 22055 O O   . HOH S 5 .   ? 53.408  79.514  22.571  1.00 41.43  ? 643 HOH E O   1 
HETATM 22056 O O   . HOH S 5 .   ? 40.473  44.361  38.617  1.00 24.26  ? 644 HOH E O   1 
HETATM 22057 O O   . HOH S 5 .   ? 57.517  43.191  18.335  1.00 35.62  ? 645 HOH E O   1 
HETATM 22058 O O   . HOH S 5 .   ? 58.238  30.811  51.803  1.00 38.87  ? 646 HOH E O   1 
HETATM 22059 O O   . HOH S 5 .   ? 73.357  54.423  42.039  1.00 32.47  ? 647 HOH E O   1 
HETATM 22060 O O   . HOH S 5 .   ? 63.990  49.303  39.274  1.00 22.32  ? 648 HOH E O   1 
HETATM 22061 O O   . HOH S 5 .   ? 63.425  58.945  60.466  1.00 32.77  ? 649 HOH E O   1 
HETATM 22062 O O   . HOH S 5 .   ? 78.033  69.283  38.578  1.00 51.44  ? 650 HOH E O   1 
HETATM 22063 O O   . HOH S 5 .   ? 45.613  38.579  46.646  1.00 34.98  ? 651 HOH E O   1 
HETATM 22064 O O   . HOH S 5 .   ? 37.519  42.841  26.343  1.00 31.17  ? 652 HOH E O   1 
HETATM 22065 O O   . HOH S 5 .   ? 54.257  82.969  23.810  1.00 30.87  ? 653 HOH E O   1 
HETATM 22066 O O   . HOH S 5 .   ? 63.406  59.335  17.782  1.00 28.64  ? 654 HOH E O   1 
HETATM 22067 O O   . HOH S 5 .   ? 24.255  60.625  27.458  1.00 33.79  ? 655 HOH E O   1 
HETATM 22068 O O   . HOH S 5 .   ? 63.446  60.617  39.344  1.00 21.80  ? 656 HOH E O   1 
HETATM 22069 O O   . HOH S 5 .   ? 52.644  66.575  37.276  1.00 34.70  ? 657 HOH E O   1 
HETATM 22070 O O   . HOH S 5 .   ? 61.480  66.459  11.565  1.00 35.06  ? 658 HOH E O   1 
HETATM 22071 O O   . HOH S 5 .   ? 40.201  72.015  29.064  1.00 33.02  ? 659 HOH E O   1 
HETATM 22072 O O   . HOH S 5 .   ? 28.882  47.045  38.393  1.00 20.97  ? 660 HOH E O   1 
HETATM 22073 O O   . HOH S 5 .   ? 58.064  68.241  13.373  1.00 42.66  ? 661 HOH E O   1 
HETATM 22074 O O   . HOH S 5 .   ? 51.242  69.264  40.013  1.00 27.20  ? 662 HOH E O   1 
HETATM 22075 O O   . HOH S 5 .   ? 67.223  66.486  37.964  1.00 32.77  ? 663 HOH E O   1 
HETATM 22076 O O   . HOH S 5 .   ? 53.707  48.439  44.303  1.00 28.34  ? 664 HOH E O   1 
HETATM 22077 O O   . HOH S 5 .   ? 64.085  43.927  22.032  1.00 33.11  ? 665 HOH E O   1 
HETATM 22078 O O   . HOH S 5 .   ? 71.820  62.056  33.766  1.00 24.27  ? 666 HOH E O   1 
HETATM 22079 O O   . HOH S 5 .   ? 51.069  31.770  24.685  1.00 38.37  ? 667 HOH E O   1 
HETATM 22080 O O   . HOH S 5 .   ? 70.719  48.740  20.584  1.00 31.95  ? 668 HOH E O   1 
HETATM 22081 O O   . HOH S 5 .   ? 40.164  52.060  11.543  1.00 38.80  ? 669 HOH E O   1 
HETATM 22082 O O   . HOH S 5 .   ? 40.659  46.881  17.050  1.00 34.29  ? 670 HOH E O   1 
HETATM 22083 O O   . HOH S 5 .   ? 66.637  70.139  26.529  1.00 26.44  ? 671 HOH E O   1 
HETATM 22084 O O   . HOH S 5 .   ? 60.312  49.696  56.113  1.00 29.85  ? 672 HOH E O   1 
HETATM 22085 O O   . HOH S 5 .   ? 47.018  50.548  62.223  1.00 29.17  ? 673 HOH E O   1 
HETATM 22086 O O   . HOH S 5 .   ? 54.150  68.720  44.479  1.00 37.41  ? 674 HOH E O   1 
HETATM 22087 O O   . HOH S 5 .   ? 72.149  56.626  43.085  1.00 28.05  ? 675 HOH E O   1 
HETATM 22088 O O   . HOH S 5 .   ? 26.356  42.942  29.692  1.00 30.68  ? 676 HOH E O   1 
HETATM 22089 O O   . HOH S 5 .   ? 71.881  59.852  34.727  1.00 28.82  ? 677 HOH E O   1 
HETATM 22090 O O   . HOH S 5 .   ? 54.871  48.164  14.018  1.00 34.95  ? 678 HOH E O   1 
HETATM 22091 O O   . HOH S 5 .   ? 67.459  55.668  33.722  1.00 25.07  ? 679 HOH E O   1 
HETATM 22092 O O   . HOH S 5 .   ? 62.310  38.282  36.820  1.00 23.46  ? 680 HOH E O   1 
HETATM 22093 O O   . HOH S 5 .   ? 47.523  46.767  47.357  1.00 24.50  ? 681 HOH E O   1 
HETATM 22094 O O   . HOH S 5 .   ? 49.630  34.031  44.401  1.00 29.99  ? 682 HOH E O   1 
HETATM 22095 O O   . HOH S 5 .   ? 67.973  58.838  28.974  1.00 33.01  ? 683 HOH E O   1 
HETATM 22096 O O   . HOH S 5 .   ? 32.617  63.716  27.688  1.00 20.90  ? 684 HOH E O   1 
HETATM 22097 O O   . HOH S 5 .   ? 73.578  65.823  35.748  1.00 40.41  ? 685 HOH E O   1 
HETATM 22098 O O   . HOH S 5 .   ? 55.194  73.759  16.347  1.00 41.27  ? 686 HOH E O   1 
HETATM 22099 O O   . HOH S 5 .   ? 53.372  36.229  50.120  1.00 46.91  ? 687 HOH E O   1 
HETATM 22100 O O   . HOH S 5 .   ? 35.545  71.163  20.118  1.00 40.12  ? 688 HOH E O   1 
HETATM 22101 O O   . HOH S 5 .   ? 39.111  63.429  38.301  1.00 20.45  ? 689 HOH E O   1 
HETATM 22102 O O   . HOH S 5 .   ? 58.179  40.749  41.045  1.00 24.40  ? 690 HOH E O   1 
HETATM 22103 O O   . HOH S 5 .   ? 29.261  67.365  22.391  1.00 24.71  ? 691 HOH E O   1 
HETATM 22104 O O   . HOH S 5 .   ? 65.109  36.401  61.985  1.00 35.88  ? 692 HOH E O   1 
HETATM 22105 O O   . HOH S 5 .   ? 30.467  76.225  29.457  1.00 30.94  ? 693 HOH E O   1 
HETATM 22106 O O   . HOH S 5 .   ? 36.863  72.706  30.093  1.00 38.02  ? 694 HOH E O   1 
HETATM 22107 O O   . HOH S 5 .   ? 38.822  71.649  32.335  1.00 36.47  ? 695 HOH E O   1 
HETATM 22108 O O   . HOH S 5 .   ? 44.825  69.084  34.087  1.00 36.86  ? 696 HOH E O   1 
HETATM 22109 O O   . HOH S 5 .   ? 58.832  47.292  23.632  1.00 25.18  ? 697 HOH E O   1 
HETATM 22110 O O   . HOH S 5 .   ? 64.017  90.826  24.120  1.00 39.80  ? 698 HOH E O   1 
HETATM 22111 O O   . HOH S 5 .   ? 53.132  38.046  25.868  1.00 33.47  ? 699 HOH E O   1 
HETATM 22112 O O   . HOH S 5 .   ? 41.195  36.841  51.487  1.00 41.77  ? 700 HOH E O   1 
HETATM 22113 O O   . HOH S 5 .   ? 43.691  54.838  62.634  1.00 42.55  ? 701 HOH E O   1 
HETATM 22114 O O   . HOH S 5 .   ? 25.617  66.793  28.170  1.00 36.85  ? 702 HOH E O   1 
HETATM 22115 O O   . HOH S 5 .   ? 63.924  57.638  53.926  1.00 34.93  ? 703 HOH E O   1 
HETATM 22116 O O   . HOH S 5 .   ? 41.599  34.572  33.530  1.00 41.91  ? 704 HOH E O   1 
HETATM 22117 O O   . HOH S 5 .   ? 60.662  62.114  10.662  1.00 41.86  ? 705 HOH E O   1 
HETATM 22118 O O   . HOH S 5 .   ? 31.291  45.082  43.891  1.00 32.81  ? 706 HOH E O   1 
HETATM 22119 O O   . HOH S 5 .   ? 43.151  72.905  28.133  1.00 27.01  ? 707 HOH E O   1 
HETATM 22120 O O   . HOH S 5 .   ? 44.702  42.668  50.665  1.00 32.87  ? 708 HOH E O   1 
HETATM 22121 O O   . HOH S 5 .   ? 50.851  66.805  14.122  1.00 29.95  ? 709 HOH E O   1 
HETATM 22122 O O   . HOH S 5 .   ? 67.916  44.231  36.188  1.00 32.91  ? 710 HOH E O   1 
HETATM 22123 O O   . HOH S 5 .   ? 68.919  77.244  21.972  1.00 29.72  ? 711 HOH E O   1 
HETATM 22124 O O   . HOH S 5 .   ? 52.470  48.887  15.214  1.00 37.23  ? 712 HOH E O   1 
HETATM 22125 O O   . HOH S 5 .   ? 52.760  78.291  34.657  1.00 57.42  ? 713 HOH E O   1 
HETATM 22126 O O   . HOH S 5 .   ? 48.074  64.230  11.144  1.00 32.06  ? 714 HOH E O   1 
HETATM 22127 O O   . HOH S 5 .   ? 21.424  55.472  25.864  1.00 33.34  ? 715 HOH E O   1 
HETATM 22128 O O   . HOH S 5 .   ? 37.277  55.416  18.896  1.00 32.00  ? 716 HOH E O   1 
HETATM 22129 O O   . HOH S 5 .   ? 26.883  67.617  23.943  1.00 24.83  ? 717 HOH E O   1 
HETATM 22130 O O   . HOH S 5 .   ? 44.058  32.676  30.521  1.00 37.27  ? 718 HOH E O   1 
HETATM 22131 O O   . HOH S 5 .   ? 58.492  71.529  28.148  1.00 28.32  ? 719 HOH E O   1 
HETATM 22132 O O   . HOH S 5 .   ? 46.357  67.981  37.897  1.00 34.64  ? 720 HOH E O   1 
HETATM 22133 O O   . HOH S 5 .   ? 50.325  42.809  16.896  1.00 34.98  ? 721 HOH E O   1 
HETATM 22134 O O   . HOH S 5 .   ? 36.663  72.151  26.473  1.00 37.43  ? 722 HOH E O   1 
HETATM 22135 O O   . HOH S 5 .   ? 52.687  47.890  49.194  1.00 34.98  ? 723 HOH E O   1 
HETATM 22136 O O   . HOH S 5 .   ? 54.522  78.871  35.495  1.00 33.16  ? 724 HOH E O   1 
HETATM 22137 O O   . HOH S 5 .   ? 52.824  66.997  34.752  1.00 32.25  ? 725 HOH E O   1 
HETATM 22138 O O   . HOH S 5 .   ? 55.100  54.139  12.885  1.00 40.31  ? 726 HOH E O   1 
HETATM 22139 O O   . HOH S 5 .   ? 60.593  67.826  44.937  1.00 34.70  ? 727 HOH E O   1 
HETATM 22140 O O   . HOH S 5 .   ? 64.599  75.954  40.759  1.00 42.72  ? 728 HOH E O   1 
HETATM 22141 O O   . HOH S 5 .   ? 57.951  69.014  38.343  1.00 31.81  ? 729 HOH E O   1 
HETATM 22142 O O   . HOH S 5 .   ? 49.728  46.756  51.287  1.00 35.15  ? 730 HOH E O   1 
HETATM 22143 O O   . HOH S 5 .   ? 49.994  64.489  12.969  1.00 28.62  ? 731 HOH E O   1 
HETATM 22144 O O   . HOH S 5 .   ? 67.799  57.856  26.320  1.00 19.28  ? 732 HOH E O   1 
HETATM 22145 O O   . HOH S 5 .   ? 57.888  66.125  55.617  1.00 32.20  ? 733 HOH E O   1 
HETATM 22146 O O   . HOH S 5 .   ? 49.718  36.320  52.673  1.00 29.84  ? 734 HOH E O   1 
HETATM 22147 O O   . HOH S 5 .   ? 45.887  46.187  6.282   1.00 41.19  ? 735 HOH E O   1 
HETATM 22148 O O   . HOH S 5 .   ? 70.181  56.035  34.222  1.00 42.31  ? 736 HOH E O   1 
HETATM 22149 O O   . HOH S 5 .   ? 64.502  74.715  43.035  1.00 44.20  ? 737 HOH E O   1 
HETATM 22150 O O   . HOH S 5 .   ? 36.638  45.123  27.521  1.00 23.09  ? 738 HOH E O   1 
HETATM 22151 O O   . HOH S 5 .   ? 63.119  63.568  38.935  1.00 29.66  ? 739 HOH E O   1 
HETATM 22152 O O   . HOH S 5 .   ? 48.043  44.144  16.779  1.00 29.93  ? 740 HOH E O   1 
HETATM 22153 O O   . HOH S 5 .   ? 50.918  46.644  16.068  1.00 45.31  ? 741 HOH E O   1 
HETATM 22154 O O   . HOH S 5 .   ? 64.925  65.478  39.475  1.00 34.63  ? 742 HOH E O   1 
HETATM 22155 O O   . HOH S 5 .   ? 50.479  40.063  16.132  1.00 40.84  ? 743 HOH E O   1 
HETATM 22156 O O   . HOH S 5 .   ? 38.047  73.872  28.167  1.00 39.21  ? 744 HOH E O   1 
HETATM 22157 O O   . HOH S 5 .   ? 48.484  38.323  56.174  1.00 38.67  ? 745 HOH E O   1 
HETATM 22158 O O   . HOH S 5 .   ? 22.340  62.537  28.339  1.00 35.94  ? 746 HOH E O   1 
HETATM 22159 O O   . HOH S 5 .   ? 50.117  47.195  48.510  1.00 41.80  ? 747 HOH E O   1 
HETATM 22160 O O   . HOH T 5 .   ? 6.728   80.148  9.213   1.00 21.89  ? 601 HOH F O   1 
HETATM 22161 O O   . HOH T 5 .   ? -4.808  89.257  30.900  1.00 29.10  ? 602 HOH F O   1 
HETATM 22162 O O   . HOH T 5 .   ? 34.286  104.605 6.868   1.00 27.93  ? 603 HOH F O   1 
HETATM 22163 O O   . HOH T 5 .   ? 18.228  66.680  24.360  1.00 29.07  ? 604 HOH F O   1 
HETATM 22164 O O   . HOH T 5 .   ? 0.181   113.502 32.978  1.00 43.98  ? 605 HOH F O   1 
HETATM 22165 O O   . HOH T 5 .   ? 13.270  113.451 2.989   1.00 40.65  ? 606 HOH F O   1 
HETATM 22166 O O   . HOH T 5 .   ? -2.039  80.337  21.486  1.00 36.46  ? 607 HOH F O   1 
HETATM 22167 O O   . HOH T 5 .   ? 6.658   105.925 16.530  1.00 38.22  ? 608 HOH F O   1 
HETATM 22168 O O   . HOH T 5 .   ? -8.512  106.542 -3.983  1.00 54.21  ? 609 HOH F O   1 
HETATM 22169 O O   . HOH T 5 .   ? 14.477  114.885 23.251  1.00 42.16  ? 610 HOH F O   1 
HETATM 22170 O O   . HOH T 5 .   ? 5.466   111.098 36.998  1.00 32.70  ? 611 HOH F O   1 
HETATM 22171 O O   . HOH T 5 .   ? 17.079  88.652  47.782  1.00 42.48  ? 612 HOH F O   1 
HETATM 22172 O O   . HOH T 5 .   ? 31.615  101.029 10.517  1.00 31.77  ? 613 HOH F O   1 
HETATM 22173 O O   . HOH T 5 .   ? 28.694  98.341  30.807  1.00 28.19  ? 614 HOH F O   1 
HETATM 22174 O O   . HOH T 5 .   ? 37.502  107.635 15.817  1.00 32.82  ? 615 HOH F O   1 
HETATM 22175 O O   . HOH T 5 .   ? 2.019   102.736 38.238  1.00 30.62  ? 616 HOH F O   1 
HETATM 22176 O O   . HOH T 5 .   ? 27.490  106.697 11.454  1.00 22.50  ? 617 HOH F O   1 
HETATM 22177 O O   . HOH T 5 .   ? 11.510  94.441  13.489  1.00 22.43  ? 618 HOH F O   1 
HETATM 22178 O O   . HOH T 5 .   ? -5.786  102.626 24.544  1.00 32.79  ? 619 HOH F O   1 
HETATM 22179 O O   . HOH T 5 .   ? -4.688  106.296 18.998  1.00 37.25  ? 620 HOH F O   1 
HETATM 22180 O O   . HOH T 5 .   ? 0.281   76.648  18.613  1.00 27.87  ? 621 HOH F O   1 
HETATM 22181 O O   . HOH T 5 .   ? -2.033  99.250  3.524   1.00 33.82  ? 622 HOH F O   1 
HETATM 22182 O O   . HOH T 5 .   ? 15.276  103.454 40.231  1.00 32.41  ? 623 HOH F O   1 
HETATM 22183 O O   . HOH T 5 .   ? 12.901  65.162  27.890  1.00 27.09  ? 624 HOH F O   1 
HETATM 22184 O O   . HOH T 5 .   ? 31.110  104.956 29.738  1.00 34.16  ? 625 HOH F O   1 
HETATM 22185 O O   . HOH T 5 .   ? 35.236  111.168 15.813  1.00 36.80  ? 626 HOH F O   1 
HETATM 22186 O O   . HOH T 5 .   ? 27.980  96.366  28.703  1.00 18.69  ? 627 HOH F O   1 
HETATM 22187 O O   . HOH T 5 .   ? 15.136  78.860  36.292  1.00 15.40  ? 628 HOH F O   1 
HETATM 22188 O O   . HOH T 5 .   ? 25.390  107.695 21.116  1.00 24.13  ? 629 HOH F O   1 
HETATM 22189 O O   . HOH T 5 .   ? -1.412  91.843  1.116   1.00 38.96  ? 630 HOH F O   1 
HETATM 22190 O O   . HOH T 5 .   ? 13.636  77.856  32.299  1.00 24.51  ? 631 HOH F O   1 
HETATM 22191 O O   . HOH T 5 .   ? 8.578   99.238  38.968  1.00 28.81  ? 632 HOH F O   1 
HETATM 22192 O O   . HOH T 5 .   ? 15.391  82.830  42.467  1.00 28.79  ? 633 HOH F O   1 
HETATM 22193 O O   . HOH T 5 .   ? 24.600  66.562  22.586  1.00 23.51  ? 634 HOH F O   1 
HETATM 22194 O O   . HOH T 5 .   ? -0.024  91.050  3.336   1.00 33.28  ? 635 HOH F O   1 
HETATM 22195 O O   . HOH T 5 .   ? 3.598   104.719 37.256  1.00 25.60  ? 636 HOH F O   1 
HETATM 22196 O O   . HOH T 5 .   ? 36.806  95.359  20.248  1.00 28.00  ? 637 HOH F O   1 
HETATM 22197 O O   . HOH T 5 .   ? 17.266  109.430 28.847  1.00 31.03  ? 638 HOH F O   1 
HETATM 22198 O O   . HOH T 5 .   ? 8.896   110.228 16.862  1.00 36.44  ? 639 HOH F O   1 
HETATM 22199 O O   . HOH T 5 .   ? 25.572  72.379  33.288  1.00 21.41  ? 640 HOH F O   1 
HETATM 22200 O O   . HOH T 5 .   ? -8.718  77.366  5.439   1.00 43.53  ? 641 HOH F O   1 
HETATM 22201 O O   . HOH T 5 .   ? 3.324   101.488 43.447  1.00 34.87  ? 642 HOH F O   1 
HETATM 22202 O O   . HOH T 5 .   ? 30.476  106.381 8.062   1.00 26.99  ? 643 HOH F O   1 
HETATM 22203 O O   . HOH T 5 .   ? 11.941  107.452 1.559   1.00 23.45  ? 644 HOH F O   1 
HETATM 22204 O O   . HOH T 5 .   ? 9.771   79.865  41.861  1.00 26.30  ? 645 HOH F O   1 
HETATM 22205 O O   . HOH T 5 .   ? 24.181  94.301  29.428  1.00 28.03  ? 646 HOH F O   1 
HETATM 22206 O O   . HOH T 5 .   ? -0.068  90.654  5.805   1.00 26.67  ? 647 HOH F O   1 
HETATM 22207 O O   . HOH T 5 .   ? 32.598  86.814  34.736  1.00 32.28  ? 648 HOH F O   1 
HETATM 22208 O O   . HOH T 5 .   ? 1.896   68.728  19.823  1.00 29.54  ? 649 HOH F O   1 
HETATM 22209 O O   . HOH T 5 .   ? 23.180  96.503  26.294  1.00 29.34  ? 650 HOH F O   1 
HETATM 22210 O O   . HOH T 5 .   ? 3.538   94.852  41.014  1.00 35.02  ? 651 HOH F O   1 
HETATM 22211 O O   . HOH T 5 .   ? 7.314   113.758 19.813  1.00 36.69  ? 652 HOH F O   1 
HETATM 22212 O O   . HOH T 5 .   ? 23.923  70.473  32.154  1.00 18.87  ? 653 HOH F O   1 
HETATM 22213 O O   . HOH T 5 .   ? -6.338  104.181 -0.925  1.00 34.73  ? 654 HOH F O   1 
HETATM 22214 O O   . HOH T 5 .   ? -3.434  91.473  8.784   1.00 20.86  ? 655 HOH F O   1 
HETATM 22215 O O   . HOH T 5 .   ? 28.610  104.206 5.567   1.00 23.51  ? 656 HOH F O   1 
HETATM 22216 O O   . HOH T 5 .   ? 24.678  68.048  25.648  1.00 32.95  ? 657 HOH F O   1 
HETATM 22217 O O   . HOH T 5 .   ? 6.105   76.135  34.939  1.00 41.63  ? 658 HOH F O   1 
HETATM 22218 O O   . HOH T 5 .   ? -4.857  87.547  18.194  1.00 32.22  ? 659 HOH F O   1 
HETATM 22219 O O   . HOH T 5 .   ? 2.662   80.387  19.185  1.00 18.63  ? 660 HOH F O   1 
HETATM 22220 O O   . HOH T 5 .   ? 8.554   98.553  11.380  1.00 32.45  ? 661 HOH F O   1 
HETATM 22221 O O   . HOH T 5 .   ? 29.976  104.247 1.184   1.00 30.74  ? 662 HOH F O   1 
HETATM 22222 O O   . HOH T 5 .   ? 15.455  91.467  0.721   1.00 30.13  ? 663 HOH F O   1 
HETATM 22223 O O   . HOH T 5 .   ? 16.299  100.160 22.470  1.00 19.42  ? 664 HOH F O   1 
HETATM 22224 O O   . HOH T 5 .   ? 5.963   93.279  4.967   1.00 31.54  ? 665 HOH F O   1 
HETATM 22225 O O   . HOH T 5 .   ? 22.383  97.959  14.067  1.00 11.76  ? 666 HOH F O   1 
HETATM 22226 O O   . HOH T 5 .   ? 20.944  105.398 8.660   1.00 35.34  ? 667 HOH F O   1 
HETATM 22227 O O   . HOH T 5 .   ? 13.917  110.890 12.103  1.00 33.09  ? 668 HOH F O   1 
HETATM 22228 O O   . HOH T 5 .   ? 47.118  110.755 33.780  1.00 36.64  ? 669 HOH F O   1 
HETATM 22229 O O   . HOH T 5 .   ? 30.307  81.509  25.935  1.00 36.12  ? 670 HOH F O   1 
HETATM 22230 O O   . HOH T 5 .   ? -5.019  110.556 0.862   1.00 46.28  ? 671 HOH F O   1 
HETATM 22231 O O   . HOH T 5 .   ? 13.892  98.218  17.093  1.00 31.07  ? 672 HOH F O   1 
HETATM 22232 O O   . HOH T 5 .   ? 21.904  90.259  43.635  1.00 28.10  ? 673 HOH F O   1 
HETATM 22233 O O   . HOH T 5 .   ? 14.507  109.366 24.846  1.00 25.17  ? 674 HOH F O   1 
HETATM 22234 O O   . HOH T 5 .   ? -2.596  84.145  3.900   1.00 31.11  ? 675 HOH F O   1 
HETATM 22235 O O   . HOH T 5 .   ? 4.322   100.251 31.994  1.00 27.50  ? 676 HOH F O   1 
HETATM 22236 O O   . HOH T 5 .   ? 4.750   90.809  2.646   1.00 30.34  ? 677 HOH F O   1 
HETATM 22237 O O   . HOH T 5 .   ? 10.956  105.043 12.460  1.00 29.18  ? 678 HOH F O   1 
HETATM 22238 O O   . HOH T 5 .   ? 7.850   92.957  7.202   1.00 23.03  ? 679 HOH F O   1 
HETATM 22239 O O   . HOH T 5 .   ? 48.013  97.666  19.404  1.00 33.88  ? 680 HOH F O   1 
HETATM 22240 O O   . HOH T 5 .   ? 5.137   91.094  -1.518  1.00 27.37  ? 681 HOH F O   1 
HETATM 22241 O O   . HOH T 5 .   ? 16.372  71.778  38.591  1.00 24.73  ? 682 HOH F O   1 
HETATM 22242 O O   . HOH T 5 .   ? 5.433   77.833  37.899  1.00 39.25  ? 683 HOH F O   1 
HETATM 22243 O O   . HOH T 5 .   ? 33.874  86.368  25.784  1.00 30.75  ? 684 HOH F O   1 
HETATM 22244 O O   . HOH T 5 .   ? 10.381  109.614 10.419  1.00 32.65  ? 685 HOH F O   1 
HETATM 22245 O O   . HOH T 5 .   ? 34.335  99.667  26.219  1.00 34.52  ? 686 HOH F O   1 
HETATM 22246 O O   . HOH T 5 .   ? 19.275  113.810 -0.937  1.00 31.71  ? 687 HOH F O   1 
HETATM 22247 O O   . HOH T 5 .   ? 30.370  82.127  29.127  1.00 21.44  ? 688 HOH F O   1 
HETATM 22248 O O   . HOH T 5 .   ? 12.027  114.586 27.693  1.00 28.49  ? 689 HOH F O   1 
HETATM 22249 O O   . HOH T 5 .   ? 22.824  83.195  17.502  1.00 21.39  ? 690 HOH F O   1 
HETATM 22250 O O   . HOH T 5 .   ? 7.388   87.354  11.575  1.00 32.58  ? 691 HOH F O   1 
HETATM 22251 O O   . HOH T 5 .   ? 21.694  113.233 24.612  1.00 42.10  ? 692 HOH F O   1 
HETATM 22252 O O   . HOH T 5 .   ? 29.334  106.671 14.887  1.00 31.26  ? 693 HOH F O   1 
HETATM 22253 O O   . HOH T 5 .   ? 11.301  71.717  16.716  1.00 20.51  ? 694 HOH F O   1 
HETATM 22254 O O   . HOH T 5 .   ? 8.468   95.617  3.471   1.00 27.22  ? 695 HOH F O   1 
HETATM 22255 O O   . HOH T 5 .   ? 1.383   94.234  35.955  1.00 35.67  ? 696 HOH F O   1 
HETATM 22256 O O   . HOH T 5 .   ? 21.509  74.828  26.821  1.00 18.29  ? 697 HOH F O   1 
HETATM 22257 O O   . HOH T 5 .   ? 4.747   80.092  25.680  1.00 31.85  ? 698 HOH F O   1 
HETATM 22258 O O   . HOH T 5 .   ? -6.308  93.074  37.856  1.00 41.65  ? 699 HOH F O   1 
HETATM 22259 O O   . HOH T 5 .   ? 32.817  99.832  12.798  1.00 28.23  ? 700 HOH F O   1 
HETATM 22260 O O   . HOH T 5 .   ? 18.327  87.280  45.488  1.00 37.24  ? 701 HOH F O   1 
HETATM 22261 O O   . HOH T 5 .   ? 1.485   100.469 39.460  1.00 39.23  ? 702 HOH F O   1 
HETATM 22262 O O   . HOH T 5 .   ? 15.585  77.260  34.022  1.00 29.73  ? 703 HOH F O   1 
HETATM 22263 O O   . HOH T 5 .   ? 36.833  94.890  16.807  1.00 35.46  ? 704 HOH F O   1 
HETATM 22264 O O   . HOH T 5 .   ? -7.026  102.865 1.339   1.00 32.09  ? 705 HOH F O   1 
HETATM 22265 O O   . HOH T 5 .   ? 16.241  116.540 16.563  1.00 37.52  ? 706 HOH F O   1 
HETATM 22266 O O   . HOH T 5 .   ? 0.772   102.408 13.810  1.00 33.79  ? 707 HOH F O   1 
HETATM 22267 O O   . HOH T 5 .   ? 22.656  109.660 3.542   1.00 33.51  ? 708 HOH F O   1 
HETATM 22268 O O   . HOH T 5 .   ? 38.356  91.100  20.001  1.00 37.44  ? 709 HOH F O   1 
HETATM 22269 O O   . HOH T 5 .   ? 30.166  103.707 8.013   1.00 34.57  ? 710 HOH F O   1 
HETATM 22270 O O   . HOH T 5 .   ? 28.994  78.757  20.386  1.00 19.53  ? 711 HOH F O   1 
HETATM 22271 O O   . HOH T 5 .   ? 22.713  110.596 11.677  1.00 31.28  ? 712 HOH F O   1 
HETATM 22272 O O   . HOH T 5 .   ? -7.846  105.364 -8.651  1.00 31.10  ? 713 HOH F O   1 
HETATM 22273 O O   . HOH T 5 .   ? -9.206  88.175  26.654  1.00 43.64  ? 714 HOH F O   1 
HETATM 22274 O O   . HOH T 5 .   ? -12.246 102.816 17.346  1.00 36.68  ? 715 HOH F O   1 
HETATM 22275 O O   . HOH T 5 .   ? 25.254  109.775 43.487  1.00 34.48  ? 716 HOH F O   1 
HETATM 22276 O O   . HOH T 5 .   ? 11.515  78.349  34.438  1.00 38.14  ? 717 HOH F O   1 
HETATM 22277 O O   . HOH T 5 .   ? 14.721  108.816 32.849  1.00 34.31  ? 718 HOH F O   1 
HETATM 22278 O O   . HOH T 5 .   ? 27.177  69.610  27.217  1.00 5.37   ? 719 HOH F O   1 
HETATM 22279 O O   . HOH T 5 .   ? 37.793  94.676  13.814  1.00 24.99  ? 720 HOH F O   1 
HETATM 22280 O O   . HOH T 5 .   ? 5.812   86.998  44.687  1.00 36.87  ? 721 HOH F O   1 
HETATM 22281 O O   . HOH T 5 .   ? 27.391  76.137  36.301  1.00 33.11  ? 722 HOH F O   1 
HETATM 22282 O O   . HOH T 5 .   ? 9.919   87.786  45.132  1.00 31.87  ? 723 HOH F O   1 
HETATM 22283 O O   . HOH T 5 .   ? -6.224  89.642  28.680  1.00 40.25  ? 724 HOH F O   1 
HETATM 22284 O O   . HOH T 5 .   ? 15.455  74.556  42.039  1.00 31.93  ? 725 HOH F O   1 
HETATM 22285 O O   . HOH T 5 .   ? 35.593  107.543 8.954   1.00 44.40  ? 726 HOH F O   1 
HETATM 22286 O O   . HOH T 5 .   ? 26.135  86.026  42.056  1.00 27.71  ? 727 HOH F O   1 
HETATM 22287 O O   . HOH T 5 .   ? -4.536  95.086  27.662  1.00 37.43  ? 728 HOH F O   1 
HETATM 22288 O O   . HOH T 5 .   ? 25.041  98.856  15.527  1.00 29.83  ? 729 HOH F O   1 
HETATM 22289 O O   . HOH T 5 .   ? 1.671   93.193  0.321   1.00 28.78  ? 730 HOH F O   1 
HETATM 22290 O O   . HOH T 5 .   ? 6.117   99.621  12.455  1.00 24.74  ? 731 HOH F O   1 
HETATM 22291 O O   . HOH T 5 .   ? 8.359   107.855 17.621  1.00 36.73  ? 732 HOH F O   1 
HETATM 22292 O O   . HOH T 5 .   ? 27.432  98.183  2.020   1.00 40.51  ? 733 HOH F O   1 
HETATM 22293 O O   . HOH T 5 .   ? 38.701  102.813 13.806  1.00 36.56  ? 734 HOH F O   1 
HETATM 22294 O O   . HOH T 5 .   ? 17.791  114.893 15.331  1.00 27.06  ? 735 HOH F O   1 
HETATM 22295 O O   . HOH T 5 .   ? -2.832  78.161  28.504  1.00 39.11  ? 736 HOH F O   1 
HETATM 22296 O O   . HOH T 5 .   ? 24.274  101.463 15.316  1.00 24.91  ? 737 HOH F O   1 
HETATM 22297 O O   . HOH T 5 .   ? -4.802  103.835 35.022  1.00 35.82  ? 738 HOH F O   1 
HETATM 22298 O O   . HOH T 5 .   ? 36.473  93.278  23.579  1.00 33.95  ? 739 HOH F O   1 
HETATM 22299 O O   . HOH T 5 .   ? 1.560   95.129  -2.390  1.00 23.18  ? 740 HOH F O   1 
HETATM 22300 O O   . HOH T 5 .   ? 24.363  68.518  30.224  1.00 17.65  ? 741 HOH F O   1 
HETATM 22301 O O   . HOH T 5 .   ? 31.369  86.162  21.314  1.00 32.79  ? 742 HOH F O   1 
HETATM 22302 O O   . HOH T 5 .   ? 18.773  113.699 24.405  1.00 33.18  ? 743 HOH F O   1 
HETATM 22303 O O   . HOH T 5 .   ? 31.943  95.415  20.379  1.00 32.58  ? 744 HOH F O   1 
HETATM 22304 O O   . HOH T 5 .   ? 0.364   105.187 33.620  1.00 35.80  ? 745 HOH F O   1 
HETATM 22305 O O   . HOH T 5 .   ? -8.275  93.825  10.602  1.00 35.88  ? 746 HOH F O   1 
HETATM 22306 O O   . HOH T 5 .   ? 4.243   92.581  39.688  1.00 27.19  ? 747 HOH F O   1 
HETATM 22307 O O   . HOH T 5 .   ? 9.405   98.626  6.393   1.00 38.24  ? 748 HOH F O   1 
HETATM 22308 O O   . HOH T 5 .   ? 2.732   95.697  -3.602  1.00 31.47  ? 749 HOH F O   1 
HETATM 22309 O O   . HOH T 5 .   ? 30.490  84.878  30.568  1.00 25.13  ? 750 HOH F O   1 
HETATM 22310 O O   . HOH T 5 .   ? 9.603   114.920 17.821  1.00 39.60  ? 751 HOH F O   1 
HETATM 22311 O O   . HOH T 5 .   ? 1.168   97.167  37.166  1.00 37.02  ? 752 HOH F O   1 
HETATM 22312 O O   . HOH T 5 .   ? 5.105   99.690  -4.779  1.00 39.44  ? 753 HOH F O   1 
HETATM 22313 O O   . HOH T 5 .   ? 19.292  89.441  44.176  1.00 25.51  ? 754 HOH F O   1 
HETATM 22314 O O   . HOH T 5 .   ? 2.987   90.749  0.376   1.00 28.06  ? 755 HOH F O   1 
HETATM 22315 O O   . HOH T 5 .   ? 2.368   91.193  38.187  1.00 35.55  ? 756 HOH F O   1 
HETATM 22316 O O   . HOH T 5 .   ? 3.170   78.867  24.114  1.00 29.73  ? 757 HOH F O   1 
HETATM 22317 O O   . HOH T 5 .   ? 29.865  113.729 32.820  1.00 36.49  ? 758 HOH F O   1 
HETATM 22318 O O   . HOH T 5 .   ? -2.415  81.210  0.490   1.00 37.02  ? 759 HOH F O   1 
HETATM 22319 O O   . HOH T 5 .   ? 16.951  109.715 31.442  1.00 36.98  ? 760 HOH F O   1 
HETATM 22320 O O   . HOH T 5 .   ? 25.340  87.816  44.170  1.00 36.37  ? 761 HOH F O   1 
HETATM 22321 O O   . HOH T 5 .   ? 22.816  87.501  44.477  1.00 33.47  ? 762 HOH F O   1 
HETATM 22322 O O   . HOH T 5 .   ? -2.011  85.506  1.506   1.00 38.82  ? 763 HOH F O   1 
HETATM 22323 O O   . HOH T 5 .   ? 14.615  80.250  43.994  1.00 31.86  ? 764 HOH F O   1 
HETATM 22324 O O   . HOH T 5 .   ? 9.037   96.106  6.414   1.00 42.99  ? 765 HOH F O   1 
HETATM 22325 O O   . HOH T 5 .   ? 32.397  107.557 6.827   1.00 38.11  ? 766 HOH F O   1 
HETATM 22326 O O   . HOH T 5 .   ? 5.726   88.952  -3.177  1.00 26.58  ? 767 HOH F O   1 
# 
