data_8XXE
# 
_entry.id   8XXE 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XXE         pdb_00008xxe 10.2210/pdb8xxe/pdb 
WWPDB D_1300044052 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XXE 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yl521gl@ustc.edu.cn 
_pdbx_contact_author.name_first         Lin 
_pdbx_contact_author.name_last          Yang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1550-6947 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, L.'   1 0000-0003-1550-6947 
'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'TtCS-intermediate complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, L.'   1 ? 
primary 'Fang, Y.J.' 2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Citrate synthase' 51100.664 3   2.3.3.16 ? ? ? 
2 non-polymer syn 'OXALOACETATE ION' 131.064   3   ?        ? ? ? 
3 non-polymer syn 'COENZYME A'       767.534   3   ?        ? ? ? 
4 non-polymer syn 'ACETYL GROUP'     44.053    1   ?        ? ? ? 
5 water       nat water              18.015    598 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        CS 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGSKLAAALE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGSKLAAALE
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'OXALOACETATE ION' OAA 
3 'COENZYME A'       COA 
4 'ACETYL GROUP'     ACE 
5 water              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   LEU n 
1 4   LYS n 
1 5   GLU n 
1 6   ARG n 
1 7   LEU n 
1 8   ALA n 
1 9   GLU n 
1 10  LEU n 
1 11  ILE n 
1 12  PRO n 
1 13  GLN n 
1 14  TRP n 
1 15  ARG n 
1 16  ALA n 
1 17  GLU n 
1 18  VAL n 
1 19  ALA n 
1 20  GLU n 
1 21  ILE n 
1 22  ARG n 
1 23  LYS n 
1 24  LYS n 
1 25  TYR n 
1 26  GLY n 
1 27  ASN n 
1 28  ARG n 
1 29  LYS n 
1 30  THR n 
1 31  MET n 
1 32  ASP n 
1 33  CYS n 
1 34  THR n 
1 35  ILE n 
1 36  GLY n 
1 37  HIS n 
1 38  ALA n 
1 39  TYR n 
1 40  GLY n 
1 41  GLY n 
1 42  MET n 
1 43  ARG n 
1 44  GLY n 
1 45  LEU n 
1 46  LYS n 
1 47  ALA n 
1 48  LEU n 
1 49  VAL n 
1 50  CYS n 
1 51  ASP n 
1 52  THR n 
1 53  SER n 
1 54  GLU n 
1 55  VAL n 
1 56  PHE n 
1 57  PRO n 
1 58  ASP n 
1 59  GLU n 
1 60  GLY n 
1 61  VAL n 
1 62  LYS n 
1 63  PHE n 
1 64  ARG n 
1 65  GLY n 
1 66  TYR n 
1 67  THR n 
1 68  ILE n 
1 69  PRO n 
1 70  GLU n 
1 71  LEU n 
1 72  ARG n 
1 73  GLU n 
1 74  GLY n 
1 75  PRO n 
1 76  HIS n 
1 77  LYS n 
1 78  LEU n 
1 79  PRO n 
1 80  THR n 
1 81  ALA n 
1 82  GLU n 
1 83  GLY n 
1 84  GLY n 
1 85  PHE n 
1 86  GLU n 
1 87  PRO n 
1 88  LEU n 
1 89  PRO n 
1 90  GLU n 
1 91  GLY n 
1 92  LEU n 
1 93  TRP n 
1 94  TYR n 
1 95  LEU n 
1 96  LEU n 
1 97  LEU n 
1 98  THR n 
1 99  GLY n 
1 100 GLU n 
1 101 LEU n 
1 102 PRO n 
1 103 THR n 
1 104 GLU n 
1 105 GLU n 
1 106 ASP n 
1 107 VAL n 
1 108 LYS n 
1 109 GLU n 
1 110 ILE n 
1 111 SER n 
1 112 ALA n 
1 113 GLU n 
1 114 PHE n 
1 115 THR n 
1 116 LYS n 
1 117 ARG n 
1 118 MET n 
1 119 GLN n 
1 120 ASN n 
1 121 VAL n 
1 122 PRO n 
1 123 GLN n 
1 124 TYR n 
1 125 VAL n 
1 126 PHE n 
1 127 ASP n 
1 128 VAL n 
1 129 LEU n 
1 130 ARG n 
1 131 ALA n 
1 132 MET n 
1 133 PRO n 
1 134 VAL n 
1 135 ASP n 
1 136 THR n 
1 137 HIS n 
1 138 PRO n 
1 139 MET n 
1 140 THR n 
1 141 MET n 
1 142 PHE n 
1 143 ALA n 
1 144 ALA n 
1 145 GLY n 
1 146 ILE n 
1 147 LEU n 
1 148 ALA n 
1 149 MET n 
1 150 GLN n 
1 151 ARG n 
1 152 GLU n 
1 153 SER n 
1 154 VAL n 
1 155 PHE n 
1 156 ALA n 
1 157 LYS n 
1 158 ARG n 
1 159 TYR n 
1 160 GLU n 
1 161 GLU n 
1 162 GLY n 
1 163 MET n 
1 164 ARG n 
1 165 ARG n 
1 166 GLU n 
1 167 GLU n 
1 168 HIS n 
1 169 TRP n 
1 170 GLU n 
1 171 ALA n 
1 172 MET n 
1 173 LEU n 
1 174 GLU n 
1 175 ASP n 
1 176 SER n 
1 177 LEU n 
1 178 ASN n 
1 179 MET n 
1 180 LEU n 
1 181 ALA n 
1 182 ALA n 
1 183 LEU n 
1 184 PRO n 
1 185 VAL n 
1 186 ILE n 
1 187 ALA n 
1 188 ALA n 
1 189 TYR n 
1 190 ILE n 
1 191 TYR n 
1 192 ARG n 
1 193 ARG n 
1 194 LYS n 
1 195 TYR n 
1 196 LYS n 
1 197 GLY n 
1 198 ASP n 
1 199 THR n 
1 200 HIS n 
1 201 ILE n 
1 202 ALA n 
1 203 PRO n 
1 204 ASP n 
1 205 PRO n 
1 206 ASN n 
1 207 LEU n 
1 208 ASP n 
1 209 TRP n 
1 210 SER n 
1 211 ALA n 
1 212 ASN n 
1 213 LEU n 
1 214 ALA n 
1 215 HIS n 
1 216 MET n 
1 217 MET n 
1 218 GLY n 
1 219 PHE n 
1 220 ASP n 
1 221 ASP n 
1 222 PHE n 
1 223 GLU n 
1 224 VAL n 
1 225 TYR n 
1 226 GLU n 
1 227 LEU n 
1 228 PHE n 
1 229 ARG n 
1 230 LEU n 
1 231 TYR n 
1 232 MET n 
1 233 PHE n 
1 234 LEU n 
1 235 HIS n 
1 236 SER n 
1 237 ASP n 
1 238 HIS n 
1 239 GLU n 
1 240 GLY n 
1 241 GLY n 
1 242 ASN n 
1 243 VAL n 
1 244 SER n 
1 245 ALA n 
1 246 HIS n 
1 247 THR n 
1 248 ASN n 
1 249 LEU n 
1 250 LEU n 
1 251 VAL n 
1 252 ASN n 
1 253 SER n 
1 254 ALA n 
1 255 TYR n 
1 256 SER n 
1 257 ASP n 
1 258 ILE n 
1 259 TYR n 
1 260 ARG n 
1 261 SER n 
1 262 PHE n 
1 263 SER n 
1 264 ALA n 
1 265 ALA n 
1 266 MET n 
1 267 ASN n 
1 268 GLY n 
1 269 LEU n 
1 270 ALA n 
1 271 GLY n 
1 272 PRO n 
1 273 LEU n 
1 274 HIS n 
1 275 GLY n 
1 276 LEU n 
1 277 ALA n 
1 278 ASN n 
1 279 GLN n 
1 280 GLU n 
1 281 VAL n 
1 282 LEU n 
1 283 ARG n 
1 284 TRP n 
1 285 ILE n 
1 286 GLN n 
1 287 MET n 
1 288 LEU n 
1 289 TYR n 
1 290 LYS n 
1 291 LYS n 
1 292 PHE n 
1 293 GLY n 
1 294 GLY n 
1 295 VAL n 
1 296 PRO n 
1 297 THR n 
1 298 LYS n 
1 299 GLU n 
1 300 GLN n 
1 301 LEU n 
1 302 GLU n 
1 303 ARG n 
1 304 PHE n 
1 305 ALA n 
1 306 TRP n 
1 307 ASP n 
1 308 THR n 
1 309 LEU n 
1 310 ASN n 
1 311 SER n 
1 312 GLY n 
1 313 GLN n 
1 314 VAL n 
1 315 ILE n 
1 316 PRO n 
1 317 GLY n 
1 318 TYR n 
1 319 GLY n 
1 320 HIS n 
1 321 ALA n 
1 322 VAL n 
1 323 LEU n 
1 324 ARG n 
1 325 VAL n 
1 326 THR n 
1 327 ASP n 
1 328 PRO n 
1 329 ARG n 
1 330 TYR n 
1 331 VAL n 
1 332 ALA n 
1 333 GLN n 
1 334 ARG n 
1 335 ASP n 
1 336 PHE n 
1 337 ALA n 
1 338 LEU n 
1 339 LYS n 
1 340 HIS n 
1 341 LEU n 
1 342 PRO n 
1 343 ASP n 
1 344 ASP n 
1 345 GLU n 
1 346 LEU n 
1 347 PHE n 
1 348 LYS n 
1 349 ILE n 
1 350 VAL n 
1 351 SER n 
1 352 LEU n 
1 353 CYS n 
1 354 TYR n 
1 355 GLU n 
1 356 VAL n 
1 357 ILE n 
1 358 PRO n 
1 359 GLU n 
1 360 VAL n 
1 361 LEU n 
1 362 LYS n 
1 363 LYS n 
1 364 HIS n 
1 365 GLY n 
1 366 LYS n 
1 367 ALA n 
1 368 LYS n 
1 369 ASN n 
1 370 PRO n 
1 371 TRP n 
1 372 PRO n 
1 373 ASN n 
1 374 VAL n 
1 375 ASP n 
1 376 ALA n 
1 377 HIS n 
1 378 SER n 
1 379 GLY n 
1 380 VAL n 
1 381 LEU n 
1 382 LEU n 
1 383 TRP n 
1 384 HIS n 
1 385 TYR n 
1 386 GLY n 
1 387 ILE n 
1 388 ARG n 
1 389 GLU n 
1 390 TYR n 
1 391 ASP n 
1 392 PHE n 
1 393 TYR n 
1 394 THR n 
1 395 VAL n 
1 396 LEU n 
1 397 PHE n 
1 398 GLY n 
1 399 VAL n 
1 400 SER n 
1 401 ARG n 
1 402 ALA n 
1 403 LEU n 
1 404 GLY n 
1 405 CYS n 
1 406 THR n 
1 407 ALA n 
1 408 GLN n 
1 409 ALA n 
1 410 ILE n 
1 411 LEU n 
1 412 VAL n 
1 413 ARG n 
1 414 GLY n 
1 415 TYR n 
1 416 MET n 
1 417 LEU n 
1 418 PRO n 
1 419 ILE n 
1 420 GLU n 
1 421 ARG n 
1 422 PRO n 
1 423 LYS n 
1 424 SER n 
1 425 ILE n 
1 426 THR n 
1 427 THR n 
1 428 ARG n 
1 429 TRP n 
1 430 VAL n 
1 431 LYS n 
1 432 GLU n 
1 433 VAL n 
1 434 ALA n 
1 435 GLU n 
1 436 SER n 
1 437 LEU n 
1 438 PRO n 
1 439 VAL n 
1 440 ALA n 
1 441 GLY n 
1 442 SER n 
1 443 LYS n 
1 444 LEU n 
1 445 ALA n 
1 446 ALA n 
1 447 ALA n 
1 448 LEU n 
1 449 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   449 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'gltA, TST_0783' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Thermosulfidibacter takaii' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     412593 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ACE non-polymer         . 'ACETYL GROUP'     ? 'C2 H4 O'             44.053  
ALA 'L-peptide linking' y ALANINE            ? 'C3 H7 N O2'          89.093  
ARG 'L-peptide linking' y ARGININE           ? 'C6 H15 N4 O2 1'      175.209 
ASN 'L-peptide linking' y ASPARAGINE         ? 'C4 H8 N2 O3'         132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'    ? 'C4 H7 N O4'          133.103 
COA non-polymer         . 'COENZYME A'       ? 'C21 H36 N7 O16 P3 S' 767.534 
CYS 'L-peptide linking' y CYSTEINE           ? 'C3 H7 N O2 S'        121.158 
GLN 'L-peptide linking' y GLUTAMINE          ? 'C5 H10 N2 O3'        146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'    ? 'C5 H9 N O4'          147.129 
GLY 'peptide linking'   y GLYCINE            ? 'C2 H5 N O2'          75.067  
HIS 'L-peptide linking' y HISTIDINE          ? 'C6 H10 N3 O2 1'      156.162 
HOH non-polymer         . WATER              ? 'H2 O'                18.015  
ILE 'L-peptide linking' y ISOLEUCINE         ? 'C6 H13 N O2'         131.173 
LEU 'L-peptide linking' y LEUCINE            ? 'C6 H13 N O2'         131.173 
LYS 'L-peptide linking' y LYSINE             ? 'C6 H15 N2 O2 1'      147.195 
MET 'L-peptide linking' y METHIONINE         ? 'C5 H11 N O2 S'       149.211 
OAA non-polymer         . 'OXALOACETATE ION' ? 'C4 H3 O5 -1'         131.064 
PHE 'L-peptide linking' y PHENYLALANINE      ? 'C9 H11 N O2'         165.189 
PRO 'L-peptide linking' y PROLINE            ? 'C5 H9 N O2'          115.130 
SER 'L-peptide linking' y SERINE             ? 'C3 H7 N O3'          105.093 
THR 'L-peptide linking' y THREONINE          ? 'C4 H9 N O3'          119.119 
TRP 'L-peptide linking' y TRYPTOPHAN         ? 'C11 H12 N2 O2'       204.225 
TYR 'L-peptide linking' y TYROSINE           ? 'C9 H11 N O3'         181.189 
VAL 'L-peptide linking' y VALINE             ? 'C5 H11 N O2'         117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   LYS 4   4   4   LYS LYS A . n 
A 1 5   GLU 5   5   5   GLU GLU A . n 
A 1 6   ARG 6   6   6   ARG ARG A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   ALA 8   8   8   ALA ALA A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  ILE 11  11  11  ILE ILE A . n 
A 1 12  PRO 12  12  12  PRO PRO A . n 
A 1 13  GLN 13  13  13  GLN GLN A . n 
A 1 14  TRP 14  14  14  TRP TRP A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  GLU 20  20  20  GLU GLU A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  LYS 23  23  23  LYS LYS A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  TYR 25  25  25  TYR TYR A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  ASN 27  27  27  ASN ASN A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  CYS 33  33  33  CYS CYS A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  ILE 35  35  35  ILE ILE A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  HIS 37  37  37  HIS HIS A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  MET 42  42  42  MET MET A . n 
A 1 43  ARG 43  43  43  ARG ARG A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  VAL 49  49  49  VAL VAL A . n 
A 1 50  CYS 50  50  50  CYS CYS A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  THR 52  52  52  THR THR A . n 
A 1 53  SER 53  53  53  SER SER A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PHE 63  63  63  PHE PHE A . n 
A 1 64  ARG 64  64  64  ARG ARG A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  TYR 66  66  66  TYR TYR A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  PRO 69  69  69  PRO PRO A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  PRO 75  75  75  PRO PRO A . n 
A 1 76  HIS 76  76  76  HIS HIS A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  GLU 82  82  82  GLU GLU A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  PHE 85  85  85  PHE PHE A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  TRP 93  93  93  TRP TRP A . n 
A 1 94  TYR 94  94  94  TYR TYR A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 GLU 105 105 105 GLU GLU A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 VAL 107 107 107 VAL VAL A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 ILE 110 110 110 ILE ILE A . n 
A 1 111 SER 111 111 111 SER SER A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 GLN 119 119 119 GLN GLN A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 VAL 121 121 121 VAL VAL A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 PHE 126 126 126 PHE PHE A . n 
A 1 127 ASP 127 127 127 ASP ASP A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 ARG 130 130 130 ARG ARG A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 HIS 137 137 137 HIS HIS A . n 
A 1 138 PRO 138 138 138 PRO PRO A . n 
A 1 139 MET 139 139 139 MET MET A . n 
A 1 140 THR 140 140 140 THR THR A . n 
A 1 141 MET 141 141 141 MET MET A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 MET 149 149 149 MET MET A . n 
A 1 150 GLN 150 150 150 GLN GLN A . n 
A 1 151 ARG 151 151 151 ARG ARG A . n 
A 1 152 GLU 152 152 152 GLU GLU A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 VAL 154 154 154 VAL VAL A . n 
A 1 155 PHE 155 155 155 PHE PHE A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 LYS 157 157 157 LYS LYS A . n 
A 1 158 ARG 158 158 158 ARG ARG A . n 
A 1 159 TYR 159 159 159 TYR TYR A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 GLU 161 161 161 GLU GLU A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 MET 163 163 163 MET MET A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 ARG 165 165 165 ARG ARG A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 GLU 167 167 167 GLU GLU A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 TRP 169 169 169 TRP TRP A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 ASP 175 175 175 ASP ASP A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 LEU 183 183 183 LEU LEU A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 TYR 189 189 189 TYR TYR A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 TYR 191 191 191 TYR TYR A . n 
A 1 192 ARG 192 192 192 ARG ARG A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 LYS 194 194 194 LYS LYS A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 GLY 197 197 197 GLY GLY A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 HIS 200 200 200 HIS HIS A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 PRO 203 203 203 PRO PRO A . n 
A 1 204 ASP 204 204 204 ASP ASP A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 ASN 206 206 206 ASN ASN A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 ASP 208 208 208 ASP ASP A . n 
A 1 209 TRP 209 209 209 TRP TRP A . n 
A 1 210 SER 210 210 210 SER SER A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 ASN 212 212 212 ASN ASN A . n 
A 1 213 LEU 213 213 213 LEU LEU A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 HIS 215 215 215 HIS HIS A . n 
A 1 216 MET 216 216 216 MET MET A . n 
A 1 217 MET 217 217 217 MET MET A . n 
A 1 218 GLY 218 218 218 GLY GLY A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 ASP 220 220 220 ASP ASP A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 PHE 222 222 222 PHE PHE A . n 
A 1 223 GLU 223 223 223 GLU GLU A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 TYR 225 225 225 TYR TYR A . n 
A 1 226 GLU 226 226 226 GLU GLU A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 PHE 228 228 228 PHE PHE A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 TYR 231 231 231 TYR TYR A . n 
A 1 232 MET 232 232 232 MET MET A . n 
A 1 233 PHE 233 233 233 PHE PHE A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 HIS 235 235 235 HIS HIS A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 HIS 238 238 238 HIS HIS A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 ASN 242 242 242 ASN ASN A . n 
A 1 243 VAL 243 243 243 VAL VAL A . n 
A 1 244 SER 244 244 244 SER SER A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 ASP 257 257 257 ASP ASP A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 TYR 259 259 259 TYR TYR A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 PHE 262 262 262 PHE PHE A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 MET 266 266 266 MET MET A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 PRO 272 272 272 PRO PRO A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 HIS 274 274 274 HIS HIS A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 GLN 279 279 279 GLN GLN A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 VAL 281 281 281 VAL VAL A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 ARG 283 283 283 ARG ARG A . n 
A 1 284 TRP 284 284 284 TRP TRP A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 GLN 286 286 286 GLN GLN A . n 
A 1 287 MET 287 287 287 MET MET A . n 
A 1 288 LEU 288 288 288 LEU LEU A . n 
A 1 289 TYR 289 289 289 TYR TYR A . n 
A 1 290 LYS 290 290 290 LYS LYS A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 PHE 292 292 292 PHE PHE A . n 
A 1 293 GLY 293 293 293 GLY GLY A . n 
A 1 294 GLY 294 294 294 GLY GLY A . n 
A 1 295 VAL 295 295 295 VAL VAL A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 GLN 300 300 300 GLN GLN A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 GLU 302 302 302 GLU GLU A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 PHE 304 304 304 PHE PHE A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 TRP 306 306 306 TRP TRP A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 THR 308 308 308 THR THR A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 TYR 318 318 318 TYR TYR A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 HIS 320 320 320 HIS HIS A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 ARG 324 324 324 ARG ARG A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 THR 326 326 326 THR THR A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 PRO 328 328 328 PRO PRO A . n 
A 1 329 ARG 329 329 329 ARG ARG A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 VAL 331 331 331 VAL VAL A . n 
A 1 332 ALA 332 332 332 ALA ALA A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 LYS 339 339 339 LYS LYS A . n 
A 1 340 HIS 340 340 340 HIS HIS A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 GLU 345 345 345 GLU GLU A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 LYS 348 348 348 LYS LYS A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 CYS 353 353 353 CYS CYS A . n 
A 1 354 TYR 354 354 354 TYR TYR A . n 
A 1 355 GLU 355 355 355 GLU GLU A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 GLU 359 359 359 GLU GLU A . n 
A 1 360 VAL 360 360 360 VAL VAL A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 LYS 362 362 362 LYS LYS A . n 
A 1 363 LYS 363 363 363 LYS LYS A . n 
A 1 364 HIS 364 364 364 HIS HIS A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 LYS 366 366 366 LYS LYS A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 LYS 368 368 368 LYS LYS A . n 
A 1 369 ASN 369 369 369 ASN ASN A . n 
A 1 370 PRO 370 370 370 PRO PRO A . n 
A 1 371 TRP 371 371 371 TRP TRP A . n 
A 1 372 PRO 372 372 372 PRO PRO A . n 
A 1 373 ASN 373 373 373 ASN ASN A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 ASP 375 375 375 ASP ASP A . n 
A 1 376 ALA 376 376 376 ALA ALA A . n 
A 1 377 HIS 377 377 377 HIS HIS A . n 
A 1 378 SER 378 378 378 SER SER A . n 
A 1 379 GLY 379 379 379 GLY GLY A . n 
A 1 380 VAL 380 380 380 VAL VAL A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 TRP 383 383 383 TRP TRP A . n 
A 1 384 HIS 384 384 384 HIS HIS A . n 
A 1 385 TYR 385 385 385 TYR TYR A . n 
A 1 386 GLY 386 386 386 GLY GLY A . n 
A 1 387 ILE 387 387 387 ILE ILE A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 GLU 389 389 389 GLU GLU A . n 
A 1 390 TYR 390 390 390 TYR TYR A . n 
A 1 391 ASP 391 391 391 ASP ASP A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 TYR 393 393 393 TYR TYR A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 VAL 395 395 395 VAL VAL A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 GLY 398 398 398 GLY GLY A . n 
A 1 399 VAL 399 399 399 VAL VAL A . n 
A 1 400 SER 400 400 400 SER SER A . n 
A 1 401 ARG 401 401 401 ARG ARG A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 GLY 404 404 404 GLY GLY A . n 
A 1 405 CYS 405 405 405 CYS CYS A . n 
A 1 406 THR 406 406 406 THR THR A . n 
A 1 407 ALA 407 407 407 ALA ALA A . n 
A 1 408 GLN 408 408 408 GLN GLN A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 ILE 410 410 410 ILE ILE A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ARG 413 413 413 ARG ARG A . n 
A 1 414 GLY 414 414 414 GLY GLY A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 MET 416 416 416 MET MET A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 PRO 418 418 418 PRO PRO A . n 
A 1 419 ILE 419 419 419 ILE ILE A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 PRO 422 422 422 PRO PRO A . n 
A 1 423 LYS 423 423 423 LYS LYS A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 THR 427 427 427 THR THR A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 TRP 429 429 429 TRP TRP A . n 
A 1 430 VAL 430 430 430 VAL VAL A . n 
A 1 431 LYS 431 431 431 LYS LYS A . n 
A 1 432 GLU 432 432 432 GLU GLU A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 GLU 435 435 435 GLU GLU A . n 
A 1 436 SER 436 436 436 SER SER A . n 
A 1 437 LEU 437 437 437 LEU LEU A . n 
A 1 438 PRO 438 438 438 PRO PRO A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 ALA 440 440 440 ALA ALA A . n 
A 1 441 GLY 441 441 441 GLY GLY A . n 
A 1 442 SER 442 442 442 SER SER A . n 
A 1 443 LYS 443 443 443 LYS ALA A . n 
A 1 444 LEU 444 444 444 LEU ALA A . n 
A 1 445 ALA 445 445 445 ALA ALA A . n 
A 1 446 ALA 446 446 446 ALA ALA A . n 
A 1 447 ALA 447 447 447 ALA ALA A . n 
A 1 448 LEU 448 448 448 LEU ALA A . n 
A 1 449 GLU 449 449 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   LYS 2   2   2   LYS LYS B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   LYS 4   4   4   LYS LYS B . n 
B 1 5   GLU 5   5   5   GLU GLU B . n 
B 1 6   ARG 6   6   6   ARG ARG B . n 
B 1 7   LEU 7   7   7   LEU LEU B . n 
B 1 8   ALA 8   8   8   ALA ALA B . n 
B 1 9   GLU 9   9   9   GLU GLU B . n 
B 1 10  LEU 10  10  10  LEU LEU B . n 
B 1 11  ILE 11  11  11  ILE ILE B . n 
B 1 12  PRO 12  12  12  PRO PRO B . n 
B 1 13  GLN 13  13  13  GLN GLN B . n 
B 1 14  TRP 14  14  14  TRP TRP B . n 
B 1 15  ARG 15  15  15  ARG ARG B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  GLU 17  17  17  GLU GLU B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  GLU 20  20  20  GLU GLU B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  ARG 22  22  22  ARG ARG B . n 
B 1 23  LYS 23  23  23  LYS LYS B . n 
B 1 24  LYS 24  24  24  LYS LYS B . n 
B 1 25  TYR 25  25  25  TYR TYR B . n 
B 1 26  GLY 26  26  26  GLY GLY B . n 
B 1 27  ASN 27  27  27  ASN ASN B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  THR 30  30  30  THR THR B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  ASP 32  32  32  ASP ASP B . n 
B 1 33  CYS 33  33  33  CYS CYS B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  ILE 35  35  35  ILE ILE B . n 
B 1 36  GLY 36  36  36  GLY GLY B . n 
B 1 37  HIS 37  37  37  HIS HIS B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  GLY 40  40  40  GLY GLY B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  MET 42  42  42  MET MET B . n 
B 1 43  ARG 43  43  43  ARG ARG B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  LYS 46  46  46  LYS LYS B . n 
B 1 47  ALA 47  47  47  ALA ALA B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  VAL 49  49  49  VAL VAL B . n 
B 1 50  CYS 50  50  50  CYS CYS B . n 
B 1 51  ASP 51  51  51  ASP ASP B . n 
B 1 52  THR 52  52  52  THR THR B . n 
B 1 53  SER 53  53  53  SER SER B . n 
B 1 54  GLU 54  54  54  GLU GLU B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  PHE 56  56  56  PHE PHE B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  VAL 61  61  61  VAL VAL B . n 
B 1 62  LYS 62  62  62  LYS LYS B . n 
B 1 63  PHE 63  63  63  PHE PHE B . n 
B 1 64  ARG 64  64  64  ARG ARG B . n 
B 1 65  GLY 65  65  65  GLY GLY B . n 
B 1 66  TYR 66  66  66  TYR TYR B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  ILE 68  68  68  ILE ILE B . n 
B 1 69  PRO 69  69  69  PRO PRO B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  GLU 73  73  73  GLU GLU B . n 
B 1 74  GLY 74  74  74  GLY GLY B . n 
B 1 75  PRO 75  75  75  PRO PRO B . n 
B 1 76  HIS 76  76  76  HIS HIS B . n 
B 1 77  LYS 77  77  77  LYS LYS B . n 
B 1 78  LEU 78  78  78  LEU LEU B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  THR 80  80  80  THR THR B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  GLU 82  82  82  GLU GLU B . n 
B 1 83  GLY 83  83  83  GLY GLY B . n 
B 1 84  GLY 84  84  84  GLY GLY B . n 
B 1 85  PHE 85  85  85  PHE PHE B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  LEU 92  92  92  LEU LEU B . n 
B 1 93  TRP 93  93  93  TRP TRP B . n 
B 1 94  TYR 94  94  94  TYR TYR B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  GLY 99  99  99  GLY GLY B . n 
B 1 100 GLU 100 100 100 GLU GLU B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 PRO 102 102 102 PRO PRO B . n 
B 1 103 THR 103 103 103 THR THR B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 GLU 105 105 105 GLU GLU B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 VAL 107 107 107 VAL VAL B . n 
B 1 108 LYS 108 108 108 LYS LYS B . n 
B 1 109 GLU 109 109 109 GLU GLU B . n 
B 1 110 ILE 110 110 110 ILE ILE B . n 
B 1 111 SER 111 111 111 SER SER B . n 
B 1 112 ALA 112 112 112 ALA ALA B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 THR 115 115 115 THR THR B . n 
B 1 116 LYS 116 116 116 LYS LYS B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 MET 118 118 118 MET MET B . n 
B 1 119 GLN 119 119 119 GLN GLN B . n 
B 1 120 ASN 120 120 120 ASN ASN B . n 
B 1 121 VAL 121 121 121 VAL VAL B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 GLN 123 123 123 GLN GLN B . n 
B 1 124 TYR 124 124 124 TYR TYR B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 PHE 126 126 126 PHE PHE B . n 
B 1 127 ASP 127 127 127 ASP ASP B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 ARG 130 130 130 ARG ARG B . n 
B 1 131 ALA 131 131 131 ALA ALA B . n 
B 1 132 MET 132 132 132 MET MET B . n 
B 1 133 PRO 133 133 133 PRO PRO B . n 
B 1 134 VAL 134 134 134 VAL VAL B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 THR 136 136 136 THR THR B . n 
B 1 137 HIS 137 137 137 HIS HIS B . n 
B 1 138 PRO 138 138 138 PRO PRO B . n 
B 1 139 MET 139 139 139 MET MET B . n 
B 1 140 THR 140 140 140 THR THR B . n 
B 1 141 MET 141 141 141 MET MET B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ALA 143 143 143 ALA ALA B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 MET 149 149 149 MET MET B . n 
B 1 150 GLN 150 150 150 GLN GLN B . n 
B 1 151 ARG 151 151 151 ARG ARG B . n 
B 1 152 GLU 152 152 152 GLU GLU B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 VAL 154 154 154 VAL VAL B . n 
B 1 155 PHE 155 155 155 PHE PHE B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 LYS 157 157 157 LYS LYS B . n 
B 1 158 ARG 158 158 158 ARG ARG B . n 
B 1 159 TYR 159 159 159 TYR TYR B . n 
B 1 160 GLU 160 160 160 GLU GLU B . n 
B 1 161 GLU 161 161 161 GLU GLU B . n 
B 1 162 GLY 162 162 162 GLY GLY B . n 
B 1 163 MET 163 163 163 MET MET B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 ARG 165 165 165 ARG ARG B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 GLU 167 167 167 GLU GLU B . n 
B 1 168 HIS 168 168 168 HIS HIS B . n 
B 1 169 TRP 169 169 169 TRP TRP B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 MET 172 172 172 MET MET B . n 
B 1 173 LEU 173 173 173 LEU LEU B . n 
B 1 174 GLU 174 174 174 GLU GLU B . n 
B 1 175 ASP 175 175 175 ASP ASP B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 ASN 178 178 178 ASN ASN B . n 
B 1 179 MET 179 179 179 MET MET B . n 
B 1 180 LEU 180 180 180 LEU LEU B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 LEU 183 183 183 LEU LEU B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 VAL 185 185 185 VAL VAL B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 TYR 189 189 189 TYR TYR B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 TYR 191 191 191 TYR TYR B . n 
B 1 192 ARG 192 192 192 ARG ARG B . n 
B 1 193 ARG 193 193 193 ARG ARG B . n 
B 1 194 LYS 194 194 194 LYS LYS B . n 
B 1 195 TYR 195 195 195 TYR TYR B . n 
B 1 196 LYS 196 196 196 LYS LYS B . n 
B 1 197 GLY 197 197 197 GLY GLY B . n 
B 1 198 ASP 198 198 198 ASP ASP B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 HIS 200 200 200 HIS HIS B . n 
B 1 201 ILE 201 201 201 ILE ILE B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 PRO 203 203 203 PRO PRO B . n 
B 1 204 ASP 204 204 204 ASP ASP B . n 
B 1 205 PRO 205 205 205 PRO PRO B . n 
B 1 206 ASN 206 206 206 ASN ASN B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 ASP 208 208 208 ASP ASP B . n 
B 1 209 TRP 209 209 209 TRP TRP B . n 
B 1 210 SER 210 210 210 SER SER B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 ASN 212 212 212 ASN ASN B . n 
B 1 213 LEU 213 213 213 LEU LEU B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 HIS 215 215 215 HIS HIS B . n 
B 1 216 MET 216 216 216 MET MET B . n 
B 1 217 MET 217 217 217 MET MET B . n 
B 1 218 GLY 218 218 218 GLY GLY B . n 
B 1 219 PHE 219 219 219 PHE PHE B . n 
B 1 220 ASP 220 220 220 ASP ASP B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 PHE 222 222 222 PHE PHE B . n 
B 1 223 GLU 223 223 223 GLU GLU B . n 
B 1 224 VAL 224 224 224 VAL VAL B . n 
B 1 225 TYR 225 225 225 TYR TYR B . n 
B 1 226 GLU 226 226 226 GLU GLU B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 PHE 228 228 228 PHE PHE B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 TYR 231 231 231 TYR TYR B . n 
B 1 232 MET 232 232 232 MET MET B . n 
B 1 233 PHE 233 233 233 PHE PHE B . n 
B 1 234 LEU 234 234 234 LEU LEU B . n 
B 1 235 HIS 235 235 235 HIS HIS B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 ASP 237 237 237 ASP ASP B . n 
B 1 238 HIS 238 238 238 HIS HIS B . n 
B 1 239 GLU 239 239 239 GLU GLU B . n 
B 1 240 GLY 240 240 240 GLY GLY B . n 
B 1 241 GLY 241 241 241 GLY GLY B . n 
B 1 242 ASN 242 242 242 ASN ASN B . n 
B 1 243 VAL 243 243 243 VAL VAL B . n 
B 1 244 SER 244 244 244 SER SER B . n 
B 1 245 ALA 245 245 245 ALA ALA B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 THR 247 247 247 THR THR B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 VAL 251 251 251 VAL VAL B . n 
B 1 252 ASN 252 252 252 ASN ASN B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 TYR 255 255 255 TYR TYR B . n 
B 1 256 SER 256 256 256 SER SER B . n 
B 1 257 ASP 257 257 257 ASP ASP B . n 
B 1 258 ILE 258 258 258 ILE ILE B . n 
B 1 259 TYR 259 259 259 TYR TYR B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 PHE 262 262 262 PHE PHE B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 MET 266 266 266 MET MET B . n 
B 1 267 ASN 267 267 267 ASN ASN B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 LEU 269 269 269 LEU LEU B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 GLY 271 271 271 GLY GLY B . n 
B 1 272 PRO 272 272 272 PRO PRO B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 HIS 274 274 274 HIS HIS B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 LEU 276 276 276 LEU LEU B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 ASN 278 278 278 ASN ASN B . n 
B 1 279 GLN 279 279 279 GLN GLN B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 VAL 281 281 281 VAL VAL B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 ARG 283 283 283 ARG ARG B . n 
B 1 284 TRP 284 284 284 TRP TRP B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 GLN 286 286 286 GLN GLN B . n 
B 1 287 MET 287 287 287 MET MET B . n 
B 1 288 LEU 288 288 288 LEU LEU B . n 
B 1 289 TYR 289 289 289 TYR TYR B . n 
B 1 290 LYS 290 290 290 LYS LYS B . n 
B 1 291 LYS 291 291 291 LYS LYS B . n 
B 1 292 PHE 292 292 292 PHE PHE B . n 
B 1 293 GLY 293 293 293 GLY GLY B . n 
B 1 294 GLY 294 294 294 GLY GLY B . n 
B 1 295 VAL 295 295 295 VAL VAL B . n 
B 1 296 PRO 296 296 296 PRO PRO B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 LYS 298 298 298 LYS LYS B . n 
B 1 299 GLU 299 299 299 GLU GLU B . n 
B 1 300 GLN 300 300 300 GLN GLN B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 GLU 302 302 302 GLU GLU B . n 
B 1 303 ARG 303 303 303 ARG ARG B . n 
B 1 304 PHE 304 304 304 PHE PHE B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 TRP 306 306 306 TRP TRP B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 THR 308 308 308 THR THR B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 GLY 312 312 312 GLY GLY B . n 
B 1 313 GLN 313 313 313 GLN GLN B . n 
B 1 314 VAL 314 314 314 VAL VAL B . n 
B 1 315 ILE 315 315 315 ILE ILE B . n 
B 1 316 PRO 316 316 316 PRO PRO B . n 
B 1 317 GLY 317 317 317 GLY GLY B . n 
B 1 318 TYR 318 318 318 TYR TYR B . n 
B 1 319 GLY 319 319 319 GLY GLY B . n 
B 1 320 HIS 320 320 320 HIS HIS B . n 
B 1 321 ALA 321 321 321 ALA ALA B . n 
B 1 322 VAL 322 322 322 VAL VAL B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 ARG 324 324 324 ARG ARG B . n 
B 1 325 VAL 325 325 325 VAL VAL B . n 
B 1 326 THR 326 326 326 THR THR B . n 
B 1 327 ASP 327 327 327 ASP ASP B . n 
B 1 328 PRO 328 328 328 PRO PRO B . n 
B 1 329 ARG 329 329 329 ARG ARG B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 VAL 331 331 331 VAL VAL B . n 
B 1 332 ALA 332 332 332 ALA ALA B . n 
B 1 333 GLN 333 333 333 GLN GLN B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 ASP 335 335 335 ASP ASP B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 LEU 338 338 338 LEU LEU B . n 
B 1 339 LYS 339 339 339 LYS LYS B . n 
B 1 340 HIS 340 340 340 HIS HIS B . n 
B 1 341 LEU 341 341 341 LEU LEU B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 GLU 345 345 345 GLU GLU B . n 
B 1 346 LEU 346 346 346 LEU LEU B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 LYS 348 348 348 LYS LYS B . n 
B 1 349 ILE 349 349 349 ILE ILE B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 SER 351 351 351 SER SER B . n 
B 1 352 LEU 352 352 352 LEU LEU B . n 
B 1 353 CYS 353 353 353 CYS CYS B . n 
B 1 354 TYR 354 354 354 TYR TYR B . n 
B 1 355 GLU 355 355 355 GLU GLU B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 ILE 357 357 357 ILE ILE B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 GLU 359 359 359 GLU GLU B . n 
B 1 360 VAL 360 360 360 VAL VAL B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 LYS 362 362 362 LYS LYS B . n 
B 1 363 LYS 363 363 363 LYS LYS B . n 
B 1 364 HIS 364 364 364 HIS HIS B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 LYS 366 366 366 LYS LYS B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 LYS 368 368 368 LYS LYS B . n 
B 1 369 ASN 369 369 369 ASN ASN B . n 
B 1 370 PRO 370 370 370 PRO PRO B . n 
B 1 371 TRP 371 371 371 TRP TRP B . n 
B 1 372 PRO 372 372 372 PRO PRO B . n 
B 1 373 ASN 373 373 373 ASN ASN B . n 
B 1 374 VAL 374 374 374 VAL VAL B . n 
B 1 375 ASP 375 375 375 ASP ASP B . n 
B 1 376 ALA 376 376 376 ALA ALA B . n 
B 1 377 HIS 377 377 377 HIS HIS B . n 
B 1 378 SER 378 378 378 SER SER B . n 
B 1 379 GLY 379 379 379 GLY GLY B . n 
B 1 380 VAL 380 380 380 VAL VAL B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 TRP 383 383 383 TRP TRP B . n 
B 1 384 HIS 384 384 384 HIS HIS B . n 
B 1 385 TYR 385 385 385 TYR TYR B . n 
B 1 386 GLY 386 386 386 GLY GLY B . n 
B 1 387 ILE 387 387 387 ILE ILE B . n 
B 1 388 ARG 388 388 388 ARG ARG B . n 
B 1 389 GLU 389 389 389 GLU GLU B . n 
B 1 390 TYR 390 390 390 TYR TYR B . n 
B 1 391 ASP 391 391 391 ASP ASP B . n 
B 1 392 PHE 392 392 392 PHE PHE B . n 
B 1 393 TYR 393 393 393 TYR TYR B . n 
B 1 394 THR 394 394 394 THR THR B . n 
B 1 395 VAL 395 395 395 VAL VAL B . n 
B 1 396 LEU 396 396 396 LEU LEU B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 GLY 398 398 398 GLY GLY B . n 
B 1 399 VAL 399 399 399 VAL VAL B . n 
B 1 400 SER 400 400 400 SER SER B . n 
B 1 401 ARG 401 401 401 ARG ARG B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 GLY 404 404 404 GLY GLY B . n 
B 1 405 CYS 405 405 405 CYS CYS B . n 
B 1 406 THR 406 406 406 THR THR B . n 
B 1 407 ALA 407 407 407 ALA ALA B . n 
B 1 408 GLN 408 408 408 GLN GLN B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 ILE 410 410 410 ILE ILE B . n 
B 1 411 LEU 411 411 411 LEU LEU B . n 
B 1 412 VAL 412 412 412 VAL VAL B . n 
B 1 413 ARG 413 413 413 ARG ARG B . n 
B 1 414 GLY 414 414 414 GLY GLY B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 MET 416 416 416 MET MET B . n 
B 1 417 LEU 417 417 417 LEU LEU B . n 
B 1 418 PRO 418 418 418 PRO PRO B . n 
B 1 419 ILE 419 419 419 ILE ILE B . n 
B 1 420 GLU 420 420 420 GLU GLU B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 PRO 422 422 422 PRO PRO B . n 
B 1 423 LYS 423 423 423 LYS LYS B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 THR 427 427 427 THR THR B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 TRP 429 429 429 TRP TRP B . n 
B 1 430 VAL 430 430 430 VAL VAL B . n 
B 1 431 LYS 431 431 431 LYS LYS B . n 
B 1 432 GLU 432 432 432 GLU GLU B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 GLU 435 435 435 GLU GLU B . n 
B 1 436 SER 436 436 436 SER SER B . n 
B 1 437 LEU 437 437 437 LEU LEU B . n 
B 1 438 PRO 438 438 438 PRO PRO B . n 
B 1 439 VAL 439 439 439 VAL VAL B . n 
B 1 440 ALA 440 440 440 ALA ALA B . n 
B 1 441 GLY 441 441 441 GLY GLY B . n 
B 1 442 SER 442 442 442 SER SER B . n 
B 1 443 LYS 443 443 443 LYS ALA B . n 
B 1 444 LEU 444 444 444 LEU ALA B . n 
B 1 445 ALA 445 445 445 ALA ALA B . n 
B 1 446 ALA 446 446 446 ALA ALA B . n 
B 1 447 ALA 447 447 447 ALA ALA B . n 
B 1 448 LEU 448 448 448 LEU ALA B . n 
B 1 449 GLU 449 449 449 GLU ALA B . n 
C 1 1   MET 1   1   1   MET MET C . n 
C 1 2   LYS 2   2   2   LYS LYS C . n 
C 1 3   LEU 3   3   3   LEU LEU C . n 
C 1 4   LYS 4   4   4   LYS LYS C . n 
C 1 5   GLU 5   5   5   GLU GLU C . n 
C 1 6   ARG 6   6   6   ARG ARG C . n 
C 1 7   LEU 7   7   7   LEU LEU C . n 
C 1 8   ALA 8   8   8   ALA ALA C . n 
C 1 9   GLU 9   9   9   GLU GLU C . n 
C 1 10  LEU 10  10  10  LEU LEU C . n 
C 1 11  ILE 11  11  11  ILE ILE C . n 
C 1 12  PRO 12  12  12  PRO PRO C . n 
C 1 13  GLN 13  13  13  GLN GLN C . n 
C 1 14  TRP 14  14  14  TRP TRP C . n 
C 1 15  ARG 15  15  15  ARG ARG C . n 
C 1 16  ALA 16  16  16  ALA ALA C . n 
C 1 17  GLU 17  17  17  GLU GLU C . n 
C 1 18  VAL 18  18  18  VAL VAL C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  GLU 20  20  20  GLU GLU C . n 
C 1 21  ILE 21  21  21  ILE ILE C . n 
C 1 22  ARG 22  22  22  ARG ARG C . n 
C 1 23  LYS 23  23  23  LYS LYS C . n 
C 1 24  LYS 24  24  24  LYS LYS C . n 
C 1 25  TYR 25  25  25  TYR TYR C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  ASN 27  27  27  ASN ASN C . n 
C 1 28  ARG 28  28  28  ARG ARG C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  THR 30  30  30  THR THR C . n 
C 1 31  MET 31  31  31  MET MET C . n 
C 1 32  ASP 32  32  32  ASP ASP C . n 
C 1 33  CYS 33  33  33  CYS CYS C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  ILE 35  35  35  ILE ILE C . n 
C 1 36  GLY 36  36  36  GLY GLY C . n 
C 1 37  HIS 37  37  37  HIS HIS C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  TYR 39  39  39  TYR TYR C . n 
C 1 40  GLY 40  40  40  GLY GLY C . n 
C 1 41  GLY 41  41  41  GLY GLY C . n 
C 1 42  MET 42  42  42  MET MET C . n 
C 1 43  ARG 43  43  43  ARG ARG C . n 
C 1 44  GLY 44  44  44  GLY GLY C . n 
C 1 45  LEU 45  45  45  LEU LEU C . n 
C 1 46  LYS 46  46  46  LYS LYS C . n 
C 1 47  ALA 47  47  47  ALA ALA C . n 
C 1 48  LEU 48  48  48  LEU LEU C . n 
C 1 49  VAL 49  49  49  VAL VAL C . n 
C 1 50  CYS 50  50  50  CYS CYS C . n 
C 1 51  ASP 51  51  51  ASP ASP C . n 
C 1 52  THR 52  52  52  THR THR C . n 
C 1 53  SER 53  53  53  SER SER C . n 
C 1 54  GLU 54  54  54  GLU GLU C . n 
C 1 55  VAL 55  55  55  VAL VAL C . n 
C 1 56  PHE 56  56  56  PHE PHE C . n 
C 1 57  PRO 57  57  57  PRO PRO C . n 
C 1 58  ASP 58  58  58  ASP ASP C . n 
C 1 59  GLU 59  59  59  GLU GLU C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  VAL 61  61  61  VAL VAL C . n 
C 1 62  LYS 62  62  62  LYS LYS C . n 
C 1 63  PHE 63  63  63  PHE PHE C . n 
C 1 64  ARG 64  64  64  ARG ARG C . n 
C 1 65  GLY 65  65  65  GLY GLY C . n 
C 1 66  TYR 66  66  66  TYR TYR C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  ILE 68  68  68  ILE ILE C . n 
C 1 69  PRO 69  69  69  PRO PRO C . n 
C 1 70  GLU 70  70  70  GLU GLU C . n 
C 1 71  LEU 71  71  71  LEU LEU C . n 
C 1 72  ARG 72  72  72  ARG ARG C . n 
C 1 73  GLU 73  73  73  GLU GLU C . n 
C 1 74  GLY 74  74  74  GLY GLY C . n 
C 1 75  PRO 75  75  75  PRO PRO C . n 
C 1 76  HIS 76  76  76  HIS HIS C . n 
C 1 77  LYS 77  77  77  LYS LYS C . n 
C 1 78  LEU 78  78  78  LEU LEU C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  THR 80  80  80  THR THR C . n 
C 1 81  ALA 81  81  81  ALA ALA C . n 
C 1 82  GLU 82  82  82  GLU GLU C . n 
C 1 83  GLY 83  83  83  GLY GLY C . n 
C 1 84  GLY 84  84  84  GLY GLY C . n 
C 1 85  PHE 85  85  85  PHE PHE C . n 
C 1 86  GLU 86  86  86  GLU GLU C . n 
C 1 87  PRO 87  87  87  PRO PRO C . n 
C 1 88  LEU 88  88  88  LEU LEU C . n 
C 1 89  PRO 89  89  89  PRO PRO C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  LEU 92  92  92  LEU LEU C . n 
C 1 93  TRP 93  93  93  TRP TRP C . n 
C 1 94  TYR 94  94  94  TYR TYR C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  LEU 96  96  96  LEU LEU C . n 
C 1 97  LEU 97  97  97  LEU LEU C . n 
C 1 98  THR 98  98  98  THR THR C . n 
C 1 99  GLY 99  99  99  GLY GLY C . n 
C 1 100 GLU 100 100 100 GLU GLU C . n 
C 1 101 LEU 101 101 101 LEU LEU C . n 
C 1 102 PRO 102 102 102 PRO PRO C . n 
C 1 103 THR 103 103 103 THR THR C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 GLU 105 105 105 GLU GLU C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 VAL 107 107 107 VAL VAL C . n 
C 1 108 LYS 108 108 108 LYS LYS C . n 
C 1 109 GLU 109 109 109 GLU GLU C . n 
C 1 110 ILE 110 110 110 ILE ILE C . n 
C 1 111 SER 111 111 111 SER SER C . n 
C 1 112 ALA 112 112 112 ALA ALA C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 PHE 114 114 114 PHE PHE C . n 
C 1 115 THR 115 115 115 THR THR C . n 
C 1 116 LYS 116 116 116 LYS LYS C . n 
C 1 117 ARG 117 117 117 ARG ARG C . n 
C 1 118 MET 118 118 118 MET MET C . n 
C 1 119 GLN 119 119 119 GLN GLN C . n 
C 1 120 ASN 120 120 120 ASN ASN C . n 
C 1 121 VAL 121 121 121 VAL VAL C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 GLN 123 123 123 GLN GLN C . n 
C 1 124 TYR 124 124 124 TYR TYR C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 PHE 126 126 126 PHE PHE C . n 
C 1 127 ASP 127 127 127 ASP ASP C . n 
C 1 128 VAL 128 128 128 VAL VAL C . n 
C 1 129 LEU 129 129 129 LEU LEU C . n 
C 1 130 ARG 130 130 130 ARG ARG C . n 
C 1 131 ALA 131 131 131 ALA ALA C . n 
C 1 132 MET 132 132 132 MET MET C . n 
C 1 133 PRO 133 133 133 PRO PRO C . n 
C 1 134 VAL 134 134 134 VAL VAL C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 THR 136 136 136 THR THR C . n 
C 1 137 HIS 137 137 137 HIS HIS C . n 
C 1 138 PRO 138 138 138 PRO PRO C . n 
C 1 139 MET 139 139 139 MET MET C . n 
C 1 140 THR 140 140 140 THR THR C . n 
C 1 141 MET 141 141 141 MET MET C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 ALA 143 143 143 ALA ALA C . n 
C 1 144 ALA 144 144 144 ALA ALA C . n 
C 1 145 GLY 145 145 145 GLY GLY C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 LEU 147 147 147 LEU LEU C . n 
C 1 148 ALA 148 148 148 ALA ALA C . n 
C 1 149 MET 149 149 149 MET MET C . n 
C 1 150 GLN 150 150 150 GLN GLN C . n 
C 1 151 ARG 151 151 151 ARG ARG C . n 
C 1 152 GLU 152 152 152 GLU GLU C . n 
C 1 153 SER 153 153 153 SER SER C . n 
C 1 154 VAL 154 154 154 VAL VAL C . n 
C 1 155 PHE 155 155 155 PHE PHE C . n 
C 1 156 ALA 156 156 156 ALA ALA C . n 
C 1 157 LYS 157 157 157 LYS LYS C . n 
C 1 158 ARG 158 158 158 ARG ARG C . n 
C 1 159 TYR 159 159 159 TYR TYR C . n 
C 1 160 GLU 160 160 160 GLU GLU C . n 
C 1 161 GLU 161 161 161 GLU GLU C . n 
C 1 162 GLY 162 162 162 GLY GLY C . n 
C 1 163 MET 163 163 163 MET MET C . n 
C 1 164 ARG 164 164 164 ARG ARG C . n 
C 1 165 ARG 165 165 165 ARG ARG C . n 
C 1 166 GLU 166 166 166 GLU GLU C . n 
C 1 167 GLU 167 167 167 GLU GLU C . n 
C 1 168 HIS 168 168 168 HIS HIS C . n 
C 1 169 TRP 169 169 169 TRP TRP C . n 
C 1 170 GLU 170 170 170 GLU GLU C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 MET 172 172 172 MET MET C . n 
C 1 173 LEU 173 173 173 LEU LEU C . n 
C 1 174 GLU 174 174 174 GLU GLU C . n 
C 1 175 ASP 175 175 175 ASP ASP C . n 
C 1 176 SER 176 176 176 SER SER C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 ASN 178 178 178 ASN ASN C . n 
C 1 179 MET 179 179 179 MET MET C . n 
C 1 180 LEU 180 180 180 LEU LEU C . n 
C 1 181 ALA 181 181 181 ALA ALA C . n 
C 1 182 ALA 182 182 182 ALA ALA C . n 
C 1 183 LEU 183 183 183 LEU LEU C . n 
C 1 184 PRO 184 184 184 PRO PRO C . n 
C 1 185 VAL 185 185 185 VAL VAL C . n 
C 1 186 ILE 186 186 186 ILE ILE C . n 
C 1 187 ALA 187 187 187 ALA ALA C . n 
C 1 188 ALA 188 188 188 ALA ALA C . n 
C 1 189 TYR 189 189 189 TYR TYR C . n 
C 1 190 ILE 190 190 190 ILE ILE C . n 
C 1 191 TYR 191 191 191 TYR TYR C . n 
C 1 192 ARG 192 192 192 ARG ARG C . n 
C 1 193 ARG 193 193 193 ARG ARG C . n 
C 1 194 LYS 194 194 194 LYS LYS C . n 
C 1 195 TYR 195 195 195 TYR TYR C . n 
C 1 196 LYS 196 196 196 LYS LYS C . n 
C 1 197 GLY 197 197 197 GLY GLY C . n 
C 1 198 ASP 198 198 198 ASP ASP C . n 
C 1 199 THR 199 199 199 THR THR C . n 
C 1 200 HIS 200 200 200 HIS HIS C . n 
C 1 201 ILE 201 201 201 ILE ILE C . n 
C 1 202 ALA 202 202 202 ALA ALA C . n 
C 1 203 PRO 203 203 203 PRO PRO C . n 
C 1 204 ASP 204 204 204 ASP ASP C . n 
C 1 205 PRO 205 205 205 PRO PRO C . n 
C 1 206 ASN 206 206 206 ASN ASN C . n 
C 1 207 LEU 207 207 207 LEU LEU C . n 
C 1 208 ASP 208 208 208 ASP ASP C . n 
C 1 209 TRP 209 209 209 TRP TRP C . n 
C 1 210 SER 210 210 210 SER SER C . n 
C 1 211 ALA 211 211 211 ALA ALA C . n 
C 1 212 ASN 212 212 212 ASN ASN C . n 
C 1 213 LEU 213 213 213 LEU LEU C . n 
C 1 214 ALA 214 214 214 ALA ALA C . n 
C 1 215 HIS 215 215 215 HIS HIS C . n 
C 1 216 MET 216 216 216 MET MET C . n 
C 1 217 MET 217 217 217 MET MET C . n 
C 1 218 GLY 218 218 218 GLY GLY C . n 
C 1 219 PHE 219 219 219 PHE PHE C . n 
C 1 220 ASP 220 220 220 ASP ASP C . n 
C 1 221 ASP 221 221 221 ASP ASP C . n 
C 1 222 PHE 222 222 222 PHE PHE C . n 
C 1 223 GLU 223 223 223 GLU GLU C . n 
C 1 224 VAL 224 224 224 VAL VAL C . n 
C 1 225 TYR 225 225 225 TYR TYR C . n 
C 1 226 GLU 226 226 226 GLU GLU C . n 
C 1 227 LEU 227 227 227 LEU LEU C . n 
C 1 228 PHE 228 228 228 PHE PHE C . n 
C 1 229 ARG 229 229 229 ARG ARG C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 TYR 231 231 231 TYR TYR C . n 
C 1 232 MET 232 232 232 MET MET C . n 
C 1 233 PHE 233 233 233 PHE PHE C . n 
C 1 234 LEU 234 234 234 LEU LEU C . n 
C 1 235 HIS 235 235 235 HIS HIS C . n 
C 1 236 SER 236 236 236 SER SER C . n 
C 1 237 ASP 237 237 237 ASP ASP C . n 
C 1 238 HIS 238 238 238 HIS HIS C . n 
C 1 239 GLU 239 239 239 GLU GLU C . n 
C 1 240 GLY 240 240 240 GLY GLY C . n 
C 1 241 GLY 241 241 241 GLY GLY C . n 
C 1 242 ASN 242 242 242 ASN ASN C . n 
C 1 243 VAL 243 243 243 VAL VAL C . n 
C 1 244 SER 244 244 244 SER SER C . n 
C 1 245 ALA 245 245 245 ALA ALA C . n 
C 1 246 HIS 246 246 246 HIS HIS C . n 
C 1 247 THR 247 247 247 THR THR C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 LEU 249 249 249 LEU LEU C . n 
C 1 250 LEU 250 250 250 LEU LEU C . n 
C 1 251 VAL 251 251 251 VAL VAL C . n 
C 1 252 ASN 252 252 252 ASN ASN C . n 
C 1 253 SER 253 253 253 SER SER C . n 
C 1 254 ALA 254 254 254 ALA ALA C . n 
C 1 255 TYR 255 255 255 TYR TYR C . n 
C 1 256 SER 256 256 256 SER SER C . n 
C 1 257 ASP 257 257 257 ASP ASP C . n 
C 1 258 ILE 258 258 258 ILE ILE C . n 
C 1 259 TYR 259 259 259 TYR TYR C . n 
C 1 260 ARG 260 260 260 ARG ARG C . n 
C 1 261 SER 261 261 261 SER SER C . n 
C 1 262 PHE 262 262 262 PHE PHE C . n 
C 1 263 SER 263 263 263 SER SER C . n 
C 1 264 ALA 264 264 264 ALA ALA C . n 
C 1 265 ALA 265 265 265 ALA ALA C . n 
C 1 266 MET 266 266 266 MET MET C . n 
C 1 267 ASN 267 267 267 ASN ASN C . n 
C 1 268 GLY 268 268 268 GLY GLY C . n 
C 1 269 LEU 269 269 269 LEU LEU C . n 
C 1 270 ALA 270 270 270 ALA ALA C . n 
C 1 271 GLY 271 271 271 GLY GLY C . n 
C 1 272 PRO 272 272 272 PRO PRO C . n 
C 1 273 LEU 273 273 273 LEU LEU C . n 
C 1 274 HIS 274 274 274 HIS HIS C . n 
C 1 275 GLY 275 275 275 GLY GLY C . n 
C 1 276 LEU 276 276 276 LEU LEU C . n 
C 1 277 ALA 277 277 277 ALA ALA C . n 
C 1 278 ASN 278 278 278 ASN ASN C . n 
C 1 279 GLN 279 279 279 GLN GLN C . n 
C 1 280 GLU 280 280 280 GLU GLU C . n 
C 1 281 VAL 281 281 281 VAL VAL C . n 
C 1 282 LEU 282 282 282 LEU LEU C . n 
C 1 283 ARG 283 283 283 ARG ARG C . n 
C 1 284 TRP 284 284 284 TRP TRP C . n 
C 1 285 ILE 285 285 285 ILE ILE C . n 
C 1 286 GLN 286 286 286 GLN GLN C . n 
C 1 287 MET 287 287 287 MET MET C . n 
C 1 288 LEU 288 288 288 LEU LEU C . n 
C 1 289 TYR 289 289 289 TYR TYR C . n 
C 1 290 LYS 290 290 290 LYS LYS C . n 
C 1 291 LYS 291 291 291 LYS LYS C . n 
C 1 292 PHE 292 292 292 PHE PHE C . n 
C 1 293 GLY 293 293 293 GLY GLY C . n 
C 1 294 GLY 294 294 294 GLY GLY C . n 
C 1 295 VAL 295 295 295 VAL VAL C . n 
C 1 296 PRO 296 296 296 PRO PRO C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 LYS 298 298 298 LYS LYS C . n 
C 1 299 GLU 299 299 299 GLU GLU C . n 
C 1 300 GLN 300 300 300 GLN GLN C . n 
C 1 301 LEU 301 301 301 LEU LEU C . n 
C 1 302 GLU 302 302 302 GLU GLU C . n 
C 1 303 ARG 303 303 303 ARG ARG C . n 
C 1 304 PHE 304 304 304 PHE PHE C . n 
C 1 305 ALA 305 305 305 ALA ALA C . n 
C 1 306 TRP 306 306 306 TRP TRP C . n 
C 1 307 ASP 307 307 307 ASP ASP C . n 
C 1 308 THR 308 308 308 THR THR C . n 
C 1 309 LEU 309 309 309 LEU LEU C . n 
C 1 310 ASN 310 310 310 ASN ASN C . n 
C 1 311 SER 311 311 311 SER SER C . n 
C 1 312 GLY 312 312 312 GLY GLY C . n 
C 1 313 GLN 313 313 313 GLN GLN C . n 
C 1 314 VAL 314 314 314 VAL VAL C . n 
C 1 315 ILE 315 315 315 ILE ILE C . n 
C 1 316 PRO 316 316 316 PRO PRO C . n 
C 1 317 GLY 317 317 317 GLY GLY C . n 
C 1 318 TYR 318 318 318 TYR TYR C . n 
C 1 319 GLY 319 319 319 GLY GLY C . n 
C 1 320 HIS 320 320 320 HIS HIS C . n 
C 1 321 ALA 321 321 321 ALA ALA C . n 
C 1 322 VAL 322 322 322 VAL VAL C . n 
C 1 323 LEU 323 323 323 LEU LEU C . n 
C 1 324 ARG 324 324 324 ARG ARG C . n 
C 1 325 VAL 325 325 325 VAL VAL C . n 
C 1 326 THR 326 326 326 THR THR C . n 
C 1 327 ASP 327 327 327 ASP ASP C . n 
C 1 328 PRO 328 328 328 PRO PRO C . n 
C 1 329 ARG 329 329 329 ARG ARG C . n 
C 1 330 TYR 330 330 330 TYR TYR C . n 
C 1 331 VAL 331 331 331 VAL VAL C . n 
C 1 332 ALA 332 332 332 ALA ALA C . n 
C 1 333 GLN 333 333 333 GLN GLN C . n 
C 1 334 ARG 334 334 334 ARG ARG C . n 
C 1 335 ASP 335 335 335 ASP ASP C . n 
C 1 336 PHE 336 336 336 PHE PHE C . n 
C 1 337 ALA 337 337 337 ALA ALA C . n 
C 1 338 LEU 338 338 338 LEU LEU C . n 
C 1 339 LYS 339 339 339 LYS LYS C . n 
C 1 340 HIS 340 340 340 HIS HIS C . n 
C 1 341 LEU 341 341 341 LEU LEU C . n 
C 1 342 PRO 342 342 342 PRO PRO C . n 
C 1 343 ASP 343 343 343 ASP ASP C . n 
C 1 344 ASP 344 344 344 ASP ASP C . n 
C 1 345 GLU 345 345 345 GLU GLU C . n 
C 1 346 LEU 346 346 346 LEU LEU C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 LYS 348 348 348 LYS LYS C . n 
C 1 349 ILE 349 349 349 ILE ILE C . n 
C 1 350 VAL 350 350 350 VAL VAL C . n 
C 1 351 SER 351 351 351 SER SER C . n 
C 1 352 LEU 352 352 352 LEU LEU C . n 
C 1 353 CYS 353 353 353 CYS CYS C . n 
C 1 354 TYR 354 354 354 TYR TYR C . n 
C 1 355 GLU 355 355 355 GLU GLU C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 ILE 357 357 357 ILE ILE C . n 
C 1 358 PRO 358 358 358 PRO PRO C . n 
C 1 359 GLU 359 359 359 GLU GLU C . n 
C 1 360 VAL 360 360 360 VAL VAL C . n 
C 1 361 LEU 361 361 361 LEU LEU C . n 
C 1 362 LYS 362 362 362 LYS LYS C . n 
C 1 363 LYS 363 363 363 LYS LYS C . n 
C 1 364 HIS 364 364 364 HIS HIS C . n 
C 1 365 GLY 365 365 365 GLY GLY C . n 
C 1 366 LYS 366 366 366 LYS LYS C . n 
C 1 367 ALA 367 367 367 ALA ALA C . n 
C 1 368 LYS 368 368 368 LYS LYS C . n 
C 1 369 ASN 369 369 369 ASN ASN C . n 
C 1 370 PRO 370 370 370 PRO PRO C . n 
C 1 371 TRP 371 371 371 TRP TRP C . n 
C 1 372 PRO 372 372 372 PRO PRO C . n 
C 1 373 ASN 373 373 373 ASN ASN C . n 
C 1 374 VAL 374 374 374 VAL VAL C . n 
C 1 375 ASP 375 375 375 ASP ASP C . n 
C 1 376 ALA 376 376 376 ALA ALA C . n 
C 1 377 HIS 377 377 377 HIS HIS C . n 
C 1 378 SER 378 378 378 SER SER C . n 
C 1 379 GLY 379 379 379 GLY GLY C . n 
C 1 380 VAL 380 380 380 VAL VAL C . n 
C 1 381 LEU 381 381 381 LEU LEU C . n 
C 1 382 LEU 382 382 382 LEU LEU C . n 
C 1 383 TRP 383 383 383 TRP TRP C . n 
C 1 384 HIS 384 384 384 HIS HIS C . n 
C 1 385 TYR 385 385 385 TYR TYR C . n 
C 1 386 GLY 386 386 386 GLY GLY C . n 
C 1 387 ILE 387 387 387 ILE ILE C . n 
C 1 388 ARG 388 388 388 ARG ARG C . n 
C 1 389 GLU 389 389 389 GLU GLU C . n 
C 1 390 TYR 390 390 390 TYR TYR C . n 
C 1 391 ASP 391 391 391 ASP ASP C . n 
C 1 392 PHE 392 392 392 PHE PHE C . n 
C 1 393 TYR 393 393 393 TYR TYR C . n 
C 1 394 THR 394 394 394 THR THR C . n 
C 1 395 VAL 395 395 395 VAL VAL C . n 
C 1 396 LEU 396 396 396 LEU LEU C . n 
C 1 397 PHE 397 397 397 PHE PHE C . n 
C 1 398 GLY 398 398 398 GLY GLY C . n 
C 1 399 VAL 399 399 399 VAL VAL C . n 
C 1 400 SER 400 400 400 SER SER C . n 
C 1 401 ARG 401 401 401 ARG ARG C . n 
C 1 402 ALA 402 402 402 ALA ALA C . n 
C 1 403 LEU 403 403 403 LEU LEU C . n 
C 1 404 GLY 404 404 404 GLY GLY C . n 
C 1 405 CYS 405 405 405 CYS CYS C . n 
C 1 406 THR 406 406 406 THR THR C . n 
C 1 407 ALA 407 407 407 ALA ALA C . n 
C 1 408 GLN 408 408 408 GLN GLN C . n 
C 1 409 ALA 409 409 409 ALA ALA C . n 
C 1 410 ILE 410 410 410 ILE ILE C . n 
C 1 411 LEU 411 411 411 LEU LEU C . n 
C 1 412 VAL 412 412 412 VAL VAL C . n 
C 1 413 ARG 413 413 413 ARG ARG C . n 
C 1 414 GLY 414 414 414 GLY GLY C . n 
C 1 415 TYR 415 415 415 TYR TYR C . n 
C 1 416 MET 416 416 416 MET MET C . n 
C 1 417 LEU 417 417 417 LEU LEU C . n 
C 1 418 PRO 418 418 418 PRO PRO C . n 
C 1 419 ILE 419 419 419 ILE ILE C . n 
C 1 420 GLU 420 420 420 GLU GLU C . n 
C 1 421 ARG 421 421 421 ARG ARG C . n 
C 1 422 PRO 422 422 422 PRO PRO C . n 
C 1 423 LYS 423 423 423 LYS LYS C . n 
C 1 424 SER 424 424 424 SER SER C . n 
C 1 425 ILE 425 425 425 ILE ILE C . n 
C 1 426 THR 426 426 426 THR THR C . n 
C 1 427 THR 427 427 427 THR THR C . n 
C 1 428 ARG 428 428 428 ARG ARG C . n 
C 1 429 TRP 429 429 429 TRP TRP C . n 
C 1 430 VAL 430 430 430 VAL VAL C . n 
C 1 431 LYS 431 431 431 LYS LYS C . n 
C 1 432 GLU 432 432 432 GLU GLU C . n 
C 1 433 VAL 433 433 433 VAL VAL C . n 
C 1 434 ALA 434 434 434 ALA ALA C . n 
C 1 435 GLU 435 435 435 GLU GLU C . n 
C 1 436 SER 436 436 436 SER SER C . n 
C 1 437 LEU 437 437 437 LEU LEU C . n 
C 1 438 PRO 438 438 438 PRO PRO C . n 
C 1 439 VAL 439 439 439 VAL VAL C . n 
C 1 440 ALA 440 440 440 ALA ALA C . n 
C 1 441 GLY 441 441 441 GLY GLY C . n 
C 1 442 SER 442 442 442 SER SER C . n 
C 1 443 LYS 443 443 ?   ?   ?   C . n 
C 1 444 LEU 444 444 ?   ?   ?   C . n 
C 1 445 ALA 445 445 ?   ?   ?   C . n 
C 1 446 ALA 446 446 ?   ?   ?   C . n 
C 1 447 ALA 447 447 ?   ?   ?   C . n 
C 1 448 LEU 448 448 ?   ?   ?   C . n 
C 1 449 GLU 449 449 ?   ?   ?   C . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 ACE ? ? ACE ? ? 'SUBJECT OF INVESTIGATION' ? 
2 COA ? ? COA ? ? 'SUBJECT OF INVESTIGATION' ? 
3 OAA ? ? OAA ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 OAA 1   501 501 OAA OAA A . 
E 3 COA 1   502 502 COA COA A . 
F 2 OAA 1   501 501 OAA OAA B . 
G 3 COA 1   502 502 COA COA B . 
H 2 OAA 1   501 501 OAA OAA C . 
I 3 COA 1   502 502 COA COA C . 
J 4 ACE 1   503 503 ACE ACE C . 
K 5 HOH 1   601 460 HOH HOH A . 
K 5 HOH 2   602 594 HOH HOH A . 
K 5 HOH 3   603 191 HOH HOH A . 
K 5 HOH 4   604 374 HOH HOH A . 
K 5 HOH 5   605 61  HOH HOH A . 
K 5 HOH 6   606 158 HOH HOH A . 
K 5 HOH 7   607 218 HOH HOH A . 
K 5 HOH 8   608 380 HOH HOH A . 
K 5 HOH 9   609 514 HOH HOH A . 
K 5 HOH 10  610 547 HOH HOH A . 
K 5 HOH 11  611 113 HOH HOH A . 
K 5 HOH 12  612 168 HOH HOH A . 
K 5 HOH 13  613 574 HOH HOH A . 
K 5 HOH 14  614 527 HOH HOH A . 
K 5 HOH 15  615 570 HOH HOH A . 
K 5 HOH 16  616 509 HOH HOH A . 
K 5 HOH 17  617 410 HOH HOH A . 
K 5 HOH 18  618 110 HOH HOH A . 
K 5 HOH 19  619 349 HOH HOH A . 
K 5 HOH 20  620 491 HOH HOH A . 
K 5 HOH 21  621 164 HOH HOH A . 
K 5 HOH 22  622 387 HOH HOH A . 
K 5 HOH 23  623 53  HOH HOH A . 
K 5 HOH 24  624 424 HOH HOH A . 
K 5 HOH 25  625 492 HOH HOH A . 
K 5 HOH 26  626 571 HOH HOH A . 
K 5 HOH 27  627 183 HOH HOH A . 
K 5 HOH 28  628 488 HOH HOH A . 
K 5 HOH 29  629 549 HOH HOH A . 
K 5 HOH 30  630 544 HOH HOH A . 
K 5 HOH 31  631 332 HOH HOH A . 
K 5 HOH 32  632 154 HOH HOH A . 
K 5 HOH 33  633 583 HOH HOH A . 
K 5 HOH 34  634 118 HOH HOH A . 
K 5 HOH 35  635 155 HOH HOH A . 
K 5 HOH 36  636 128 HOH HOH A . 
K 5 HOH 37  637 51  HOH HOH A . 
K 5 HOH 38  638 378 HOH HOH A . 
K 5 HOH 39  639 25  HOH HOH A . 
K 5 HOH 40  640 198 HOH HOH A . 
K 5 HOH 41  641 322 HOH HOH A . 
K 5 HOH 42  642 368 HOH HOH A . 
K 5 HOH 43  643 501 HOH HOH A . 
K 5 HOH 44  644 530 HOH HOH A . 
K 5 HOH 45  645 6   HOH HOH A . 
K 5 HOH 46  646 486 HOH HOH A . 
K 5 HOH 47  647 559 HOH HOH A . 
K 5 HOH 48  648 421 HOH HOH A . 
K 5 HOH 49  649 552 HOH HOH A . 
K 5 HOH 50  650 400 HOH HOH A . 
K 5 HOH 51  651 7   HOH HOH A . 
K 5 HOH 52  652 333 HOH HOH A . 
K 5 HOH 53  653 259 HOH HOH A . 
K 5 HOH 54  654 50  HOH HOH A . 
K 5 HOH 55  655 569 HOH HOH A . 
K 5 HOH 56  656 132 HOH HOH A . 
K 5 HOH 57  657 589 HOH HOH A . 
K 5 HOH 58  658 190 HOH HOH A . 
K 5 HOH 59  659 163 HOH HOH A . 
K 5 HOH 60  660 211 HOH HOH A . 
K 5 HOH 61  661 318 HOH HOH A . 
K 5 HOH 62  662 69  HOH HOH A . 
K 5 HOH 63  663 584 HOH HOH A . 
K 5 HOH 64  664 543 HOH HOH A . 
K 5 HOH 65  665 247 HOH HOH A . 
K 5 HOH 66  666 522 HOH HOH A . 
K 5 HOH 67  667 401 HOH HOH A . 
K 5 HOH 68  668 538 HOH HOH A . 
K 5 HOH 69  669 179 HOH HOH A . 
K 5 HOH 70  670 324 HOH HOH A . 
K 5 HOH 71  671 344 HOH HOH A . 
K 5 HOH 72  672 310 HOH HOH A . 
K 5 HOH 73  673 406 HOH HOH A . 
K 5 HOH 74  674 311 HOH HOH A . 
K 5 HOH 75  675 392 HOH HOH A . 
K 5 HOH 76  676 193 HOH HOH A . 
K 5 HOH 77  677 443 HOH HOH A . 
K 5 HOH 78  678 156 HOH HOH A . 
K 5 HOH 79  679 568 HOH HOH A . 
K 5 HOH 80  680 546 HOH HOH A . 
K 5 HOH 81  681 351 HOH HOH A . 
K 5 HOH 82  682 126 HOH HOH A . 
K 5 HOH 83  683 56  HOH HOH A . 
K 5 HOH 84  684 72  HOH HOH A . 
K 5 HOH 85  685 244 HOH HOH A . 
K 5 HOH 86  686 320 HOH HOH A . 
K 5 HOH 87  687 144 HOH HOH A . 
K 5 HOH 88  688 102 HOH HOH A . 
K 5 HOH 89  689 535 HOH HOH A . 
K 5 HOH 90  690 14  HOH HOH A . 
K 5 HOH 91  691 43  HOH HOH A . 
K 5 HOH 92  692 207 HOH HOH A . 
K 5 HOH 93  693 55  HOH HOH A . 
K 5 HOH 94  694 212 HOH HOH A . 
K 5 HOH 95  695 145 HOH HOH A . 
K 5 HOH 96  696 174 HOH HOH A . 
K 5 HOH 97  697 250 HOH HOH A . 
K 5 HOH 98  698 215 HOH HOH A . 
K 5 HOH 99  699 398 HOH HOH A . 
K 5 HOH 100 700 93  HOH HOH A . 
K 5 HOH 101 701 123 HOH HOH A . 
K 5 HOH 102 702 507 HOH HOH A . 
K 5 HOH 103 703 364 HOH HOH A . 
K 5 HOH 104 704 511 HOH HOH A . 
K 5 HOH 105 705 384 HOH HOH A . 
K 5 HOH 106 706 222 HOH HOH A . 
K 5 HOH 107 707 325 HOH HOH A . 
K 5 HOH 108 708 42  HOH HOH A . 
K 5 HOH 109 709 453 HOH HOH A . 
K 5 HOH 110 710 315 HOH HOH A . 
K 5 HOH 111 711 577 HOH HOH A . 
K 5 HOH 112 712 37  HOH HOH A . 
K 5 HOH 113 713 165 HOH HOH A . 
K 5 HOH 114 714 307 HOH HOH A . 
K 5 HOH 115 715 157 HOH HOH A . 
K 5 HOH 116 716 563 HOH HOH A . 
K 5 HOH 117 717 292 HOH HOH A . 
K 5 HOH 118 718 181 HOH HOH A . 
K 5 HOH 119 719 386 HOH HOH A . 
K 5 HOH 120 720 433 HOH HOH A . 
K 5 HOH 121 721 308 HOH HOH A . 
K 5 HOH 122 722 426 HOH HOH A . 
K 5 HOH 123 723 335 HOH HOH A . 
K 5 HOH 124 724 397 HOH HOH A . 
K 5 HOH 125 725 195 HOH HOH A . 
K 5 HOH 126 726 362 HOH HOH A . 
K 5 HOH 127 727 46  HOH HOH A . 
K 5 HOH 128 728 63  HOH HOH A . 
K 5 HOH 129 729 352 HOH HOH A . 
K 5 HOH 130 730 180 HOH HOH A . 
K 5 HOH 131 731 68  HOH HOH A . 
K 5 HOH 132 732 13  HOH HOH A . 
K 5 HOH 133 733 182 HOH HOH A . 
K 5 HOH 134 734 80  HOH HOH A . 
K 5 HOH 135 735 82  HOH HOH A . 
K 5 HOH 136 736 274 HOH HOH A . 
K 5 HOH 137 737 54  HOH HOH A . 
K 5 HOH 138 738 239 HOH HOH A . 
K 5 HOH 139 739 411 HOH HOH A . 
K 5 HOH 140 740 521 HOH HOH A . 
K 5 HOH 141 741 334 HOH HOH A . 
K 5 HOH 142 742 439 HOH HOH A . 
K 5 HOH 143 743 361 HOH HOH A . 
K 5 HOH 144 744 489 HOH HOH A . 
K 5 HOH 145 745 518 HOH HOH A . 
K 5 HOH 146 746 385 HOH HOH A . 
K 5 HOH 147 747 298 HOH HOH A . 
K 5 HOH 148 748 281 HOH HOH A . 
K 5 HOH 149 749 416 HOH HOH A . 
K 5 HOH 150 750 241 HOH HOH A . 
K 5 HOH 151 751 456 HOH HOH A . 
K 5 HOH 152 752 473 HOH HOH A . 
K 5 HOH 153 753 5   HOH HOH A . 
K 5 HOH 154 754 499 HOH HOH A . 
K 5 HOH 155 755 148 HOH HOH A . 
K 5 HOH 156 756 425 HOH HOH A . 
K 5 HOH 157 757 529 HOH HOH A . 
K 5 HOH 158 758 185 HOH HOH A . 
K 5 HOH 159 759 210 HOH HOH A . 
K 5 HOH 160 760 22  HOH HOH A . 
K 5 HOH 161 761 523 HOH HOH A . 
K 5 HOH 162 762 62  HOH HOH A . 
K 5 HOH 163 763 1   HOH HOH A . 
K 5 HOH 164 764 273 HOH HOH A . 
K 5 HOH 165 765 517 HOH HOH A . 
K 5 HOH 166 766 348 HOH HOH A . 
K 5 HOH 167 767 317 HOH HOH A . 
K 5 HOH 168 768 117 HOH HOH A . 
K 5 HOH 169 769 302 HOH HOH A . 
K 5 HOH 170 770 342 HOH HOH A . 
K 5 HOH 171 771 33  HOH HOH A . 
K 5 HOH 172 772 461 HOH HOH A . 
K 5 HOH 173 773 471 HOH HOH A . 
K 5 HOH 174 774 575 HOH HOH A . 
K 5 HOH 175 775 591 HOH HOH A . 
K 5 HOH 176 776 282 HOH HOH A . 
K 5 HOH 177 777 607 HOH HOH A . 
K 5 HOH 178 778 604 HOH HOH A . 
K 5 HOH 179 779 605 HOH HOH A . 
K 5 HOH 180 780 539 HOH HOH A . 
K 5 HOH 181 781 442 HOH HOH A . 
K 5 HOH 182 782 606 HOH HOH A . 
K 5 HOH 183 783 338 HOH HOH A . 
K 5 HOH 184 784 581 HOH HOH A . 
K 5 HOH 185 785 326 HOH HOH A . 
K 5 HOH 186 786 430 HOH HOH A . 
K 5 HOH 187 787 469 HOH HOH A . 
L 5 HOH 1   601 528 HOH HOH B . 
L 5 HOH 2   602 47  HOH HOH B . 
L 5 HOH 3   603 524 HOH HOH B . 
L 5 HOH 4   604 278 HOH HOH B . 
L 5 HOH 5   605 545 HOH HOH B . 
L 5 HOH 6   606 417 HOH HOH B . 
L 5 HOH 7   607 434 HOH HOH B . 
L 5 HOH 8   608 578 HOH HOH B . 
L 5 HOH 9   609 370 HOH HOH B . 
L 5 HOH 10  610 10  HOH HOH B . 
L 5 HOH 11  611 576 HOH HOH B . 
L 5 HOH 12  612 213 HOH HOH B . 
L 5 HOH 13  613 597 HOH HOH B . 
L 5 HOH 14  614 532 HOH HOH B . 
L 5 HOH 15  615 291 HOH HOH B . 
L 5 HOH 16  616 188 HOH HOH B . 
L 5 HOH 17  617 104 HOH HOH B . 
L 5 HOH 18  618 295 HOH HOH B . 
L 5 HOH 19  619 296 HOH HOH B . 
L 5 HOH 20  620 312 HOH HOH B . 
L 5 HOH 21  621 220 HOH HOH B . 
L 5 HOH 22  622 252 HOH HOH B . 
L 5 HOH 23  623 277 HOH HOH B . 
L 5 HOH 24  624 81  HOH HOH B . 
L 5 HOH 25  625 150 HOH HOH B . 
L 5 HOH 26  626 229 HOH HOH B . 
L 5 HOH 27  627 409 HOH HOH B . 
L 5 HOH 28  628 540 HOH HOH B . 
L 5 HOH 29  629 304 HOH HOH B . 
L 5 HOH 30  630 8   HOH HOH B . 
L 5 HOH 31  631 536 HOH HOH B . 
L 5 HOH 32  632 498 HOH HOH B . 
L 5 HOH 33  633 214 HOH HOH B . 
L 5 HOH 34  634 441 HOH HOH B . 
L 5 HOH 35  635 371 HOH HOH B . 
L 5 HOH 36  636 436 HOH HOH B . 
L 5 HOH 37  637 120 HOH HOH B . 
L 5 HOH 38  638 196 HOH HOH B . 
L 5 HOH 39  639 279 HOH HOH B . 
L 5 HOH 40  640 554 HOH HOH B . 
L 5 HOH 41  641 537 HOH HOH B . 
L 5 HOH 42  642 71  HOH HOH B . 
L 5 HOH 43  643 313 HOH HOH B . 
L 5 HOH 44  644 267 HOH HOH B . 
L 5 HOH 45  645 248 HOH HOH B . 
L 5 HOH 46  646 448 HOH HOH B . 
L 5 HOH 47  647 494 HOH HOH B . 
L 5 HOH 48  648 258 HOH HOH B . 
L 5 HOH 49  649 224 HOH HOH B . 
L 5 HOH 50  650 99  HOH HOH B . 
L 5 HOH 51  651 67  HOH HOH B . 
L 5 HOH 52  652 130 HOH HOH B . 
L 5 HOH 53  653 329 HOH HOH B . 
L 5 HOH 54  654 504 HOH HOH B . 
L 5 HOH 55  655 58  HOH HOH B . 
L 5 HOH 56  656 355 HOH HOH B . 
L 5 HOH 57  657 32  HOH HOH B . 
L 5 HOH 58  658 533 HOH HOH B . 
L 5 HOH 59  659 389 HOH HOH B . 
L 5 HOH 60  660 582 HOH HOH B . 
L 5 HOH 61  661 289 HOH HOH B . 
L 5 HOH 62  662 454 HOH HOH B . 
L 5 HOH 63  663 447 HOH HOH B . 
L 5 HOH 64  664 112 HOH HOH B . 
L 5 HOH 65  665 553 HOH HOH B . 
L 5 HOH 66  666 422 HOH HOH B . 
L 5 HOH 67  667 161 HOH HOH B . 
L 5 HOH 68  668 579 HOH HOH B . 
L 5 HOH 69  669 142 HOH HOH B . 
L 5 HOH 70  670 490 HOH HOH B . 
L 5 HOH 71  671 217 HOH HOH B . 
L 5 HOH 72  672 236 HOH HOH B . 
L 5 HOH 73  673 238 HOH HOH B . 
L 5 HOH 74  674 176 HOH HOH B . 
L 5 HOH 75  675 91  HOH HOH B . 
L 5 HOH 76  676 347 HOH HOH B . 
L 5 HOH 77  677 34  HOH HOH B . 
L 5 HOH 78  678 77  HOH HOH B . 
L 5 HOH 79  679 382 HOH HOH B . 
L 5 HOH 80  680 405 HOH HOH B . 
L 5 HOH 81  681 12  HOH HOH B . 
L 5 HOH 82  682 558 HOH HOH B . 
L 5 HOH 83  683 45  HOH HOH B . 
L 5 HOH 84  684 26  HOH HOH B . 
L 5 HOH 85  685 266 HOH HOH B . 
L 5 HOH 86  686 585 HOH HOH B . 
L 5 HOH 87  687 129 HOH HOH B . 
L 5 HOH 88  688 394 HOH HOH B . 
L 5 HOH 89  689 402 HOH HOH B . 
L 5 HOH 90  690 254 HOH HOH B . 
L 5 HOH 91  691 40  HOH HOH B . 
L 5 HOH 92  692 319 HOH HOH B . 
L 5 HOH 93  693 49  HOH HOH B . 
L 5 HOH 94  694 152 HOH HOH B . 
L 5 HOH 95  695 88  HOH HOH B . 
L 5 HOH 96  696 264 HOH HOH B . 
L 5 HOH 97  697 225 HOH HOH B . 
L 5 HOH 98  698 86  HOH HOH B . 
L 5 HOH 99  699 592 HOH HOH B . 
L 5 HOH 100 700 111 HOH HOH B . 
L 5 HOH 101 701 265 HOH HOH B . 
L 5 HOH 102 702 297 HOH HOH B . 
L 5 HOH 103 703 139 HOH HOH B . 
L 5 HOH 104 704 294 HOH HOH B . 
L 5 HOH 105 705 284 HOH HOH B . 
L 5 HOH 106 706 44  HOH HOH B . 
L 5 HOH 107 707 115 HOH HOH B . 
L 5 HOH 108 708 96  HOH HOH B . 
L 5 HOH 109 709 116 HOH HOH B . 
L 5 HOH 110 710 431 HOH HOH B . 
L 5 HOH 111 711 300 HOH HOH B . 
L 5 HOH 112 712 84  HOH HOH B . 
L 5 HOH 113 713 269 HOH HOH B . 
L 5 HOH 114 714 23  HOH HOH B . 
L 5 HOH 115 715 600 HOH HOH B . 
L 5 HOH 116 716 59  HOH HOH B . 
L 5 HOH 117 717 221 HOH HOH B . 
L 5 HOH 118 718 253 HOH HOH B . 
L 5 HOH 119 719 38  HOH HOH B . 
L 5 HOH 120 720 556 HOH HOH B . 
L 5 HOH 121 721 36  HOH HOH B . 
L 5 HOH 122 722 143 HOH HOH B . 
L 5 HOH 123 723 75  HOH HOH B . 
L 5 HOH 124 724 203 HOH HOH B . 
L 5 HOH 125 725 260 HOH HOH B . 
L 5 HOH 126 726 399 HOH HOH B . 
L 5 HOH 127 727 590 HOH HOH B . 
L 5 HOH 128 728 316 HOH HOH B . 
L 5 HOH 129 729 366 HOH HOH B . 
L 5 HOH 130 730 283 HOH HOH B . 
L 5 HOH 131 731 403 HOH HOH B . 
L 5 HOH 132 732 587 HOH HOH B . 
L 5 HOH 133 733 223 HOH HOH B . 
L 5 HOH 134 734 363 HOH HOH B . 
L 5 HOH 135 735 76  HOH HOH B . 
L 5 HOH 136 736 503 HOH HOH B . 
L 5 HOH 137 737 232 HOH HOH B . 
L 5 HOH 138 738 376 HOH HOH B . 
L 5 HOH 139 739 257 HOH HOH B . 
L 5 HOH 140 740 534 HOH HOH B . 
L 5 HOH 141 741 240 HOH HOH B . 
L 5 HOH 142 742 285 HOH HOH B . 
L 5 HOH 143 743 293 HOH HOH B . 
L 5 HOH 144 744 209 HOH HOH B . 
L 5 HOH 145 745 255 HOH HOH B . 
L 5 HOH 146 746 423 HOH HOH B . 
L 5 HOH 147 747 233 HOH HOH B . 
L 5 HOH 148 748 516 HOH HOH B . 
L 5 HOH 149 749 235 HOH HOH B . 
L 5 HOH 150 750 551 HOH HOH B . 
L 5 HOH 151 751 243 HOH HOH B . 
L 5 HOH 152 752 204 HOH HOH B . 
L 5 HOH 153 753 477 HOH HOH B . 
L 5 HOH 154 754 208 HOH HOH B . 
L 5 HOH 155 755 172 HOH HOH B . 
L 5 HOH 156 756 497 HOH HOH B . 
L 5 HOH 157 757 100 HOH HOH B . 
L 5 HOH 158 758 173 HOH HOH B . 
L 5 HOH 159 759 566 HOH HOH B . 
L 5 HOH 160 760 141 HOH HOH B . 
L 5 HOH 161 761 565 HOH HOH B . 
L 5 HOH 162 762 420 HOH HOH B . 
L 5 HOH 163 763 309 HOH HOH B . 
L 5 HOH 164 764 151 HOH HOH B . 
L 5 HOH 165 765 160 HOH HOH B . 
L 5 HOH 166 766 413 HOH HOH B . 
L 5 HOH 167 767 505 HOH HOH B . 
L 5 HOH 168 768 167 HOH HOH B . 
L 5 HOH 169 769 305 HOH HOH B . 
L 5 HOH 170 770 16  HOH HOH B . 
L 5 HOH 171 771 468 HOH HOH B . 
L 5 HOH 172 772 375 HOH HOH B . 
L 5 HOH 173 773 3   HOH HOH B . 
L 5 HOH 174 774 438 HOH HOH B . 
L 5 HOH 175 775 470 HOH HOH B . 
L 5 HOH 176 776 249 HOH HOH B . 
L 5 HOH 177 777 107 HOH HOH B . 
L 5 HOH 178 778 472 HOH HOH B . 
L 5 HOH 179 779 515 HOH HOH B . 
L 5 HOH 180 780 429 HOH HOH B . 
L 5 HOH 181 781 341 HOH HOH B . 
L 5 HOH 182 782 474 HOH HOH B . 
L 5 HOH 183 783 359 HOH HOH B . 
L 5 HOH 184 784 482 HOH HOH B . 
L 5 HOH 185 785 391 HOH HOH B . 
L 5 HOH 186 786 481 HOH HOH B . 
L 5 HOH 187 787 301 HOH HOH B . 
L 5 HOH 188 788 432 HOH HOH B . 
L 5 HOH 189 789 475 HOH HOH B . 
L 5 HOH 190 790 593 HOH HOH B . 
L 5 HOH 191 791 526 HOH HOH B . 
L 5 HOH 192 792 603 HOH HOH B . 
L 5 HOH 193 793 445 HOH HOH B . 
L 5 HOH 194 794 476 HOH HOH B . 
L 5 HOH 195 795 390 HOH HOH B . 
L 5 HOH 196 796 194 HOH HOH B . 
L 5 HOH 197 797 452 HOH HOH B . 
L 5 HOH 198 798 479 HOH HOH B . 
M 5 HOH 1   601 383 HOH HOH C . 
M 5 HOH 2   602 337 HOH HOH C . 
M 5 HOH 3   603 550 HOH HOH C . 
M 5 HOH 4   604 345 HOH HOH C . 
M 5 HOH 5   605 331 HOH HOH C . 
M 5 HOH 6   606 573 HOH HOH C . 
M 5 HOH 7   607 226 HOH HOH C . 
M 5 HOH 8   608 510 HOH HOH C . 
M 5 HOH 9   609 408 HOH HOH C . 
M 5 HOH 10  610 11  HOH HOH C . 
M 5 HOH 11  611 512 HOH HOH C . 
M 5 HOH 12  612 109 HOH HOH C . 
M 5 HOH 13  613 346 HOH HOH C . 
M 5 HOH 14  614 146 HOH HOH C . 
M 5 HOH 15  615 187 HOH HOH C . 
M 5 HOH 16  616 271 HOH HOH C . 
M 5 HOH 17  617 343 HOH HOH C . 
M 5 HOH 18  618 437 HOH HOH C . 
M 5 HOH 19  619 136 HOH HOH C . 
M 5 HOH 20  620 137 HOH HOH C . 
M 5 HOH 21  621 395 HOH HOH C . 
M 5 HOH 22  622 580 HOH HOH C . 
M 5 HOH 23  623 101 HOH HOH C . 
M 5 HOH 24  624 184 HOH HOH C . 
M 5 HOH 25  625 287 HOH HOH C . 
M 5 HOH 26  626 228 HOH HOH C . 
M 5 HOH 27  627 428 HOH HOH C . 
M 5 HOH 28  628 562 HOH HOH C . 
M 5 HOH 29  629 28  HOH HOH C . 
M 5 HOH 30  630 541 HOH HOH C . 
M 5 HOH 31  631 275 HOH HOH C . 
M 5 HOH 32  632 85  HOH HOH C . 
M 5 HOH 33  633 95  HOH HOH C . 
M 5 HOH 34  634 567 HOH HOH C . 
M 5 HOH 35  635 138 HOH HOH C . 
M 5 HOH 36  636 242 HOH HOH C . 
M 5 HOH 37  637 446 HOH HOH C . 
M 5 HOH 38  638 87  HOH HOH C . 
M 5 HOH 39  639 83  HOH HOH C . 
M 5 HOH 40  640 202 HOH HOH C . 
M 5 HOH 41  641 500 HOH HOH C . 
M 5 HOH 42  642 572 HOH HOH C . 
M 5 HOH 43  643 20  HOH HOH C . 
M 5 HOH 44  644 306 HOH HOH C . 
M 5 HOH 45  645 57  HOH HOH C . 
M 5 HOH 46  646 303 HOH HOH C . 
M 5 HOH 47  647 227 HOH HOH C . 
M 5 HOH 48  648 328 HOH HOH C . 
M 5 HOH 49  649 48  HOH HOH C . 
M 5 HOH 50  650 601 HOH HOH C . 
M 5 HOH 51  651 484 HOH HOH C . 
M 5 HOH 52  652 451 HOH HOH C . 
M 5 HOH 53  653 127 HOH HOH C . 
M 5 HOH 54  654 74  HOH HOH C . 
M 5 HOH 55  655 175 HOH HOH C . 
M 5 HOH 56  656 450 HOH HOH C . 
M 5 HOH 57  657 350 HOH HOH C . 
M 5 HOH 58  658 276 HOH HOH C . 
M 5 HOH 59  659 4   HOH HOH C . 
M 5 HOH 60  660 373 HOH HOH C . 
M 5 HOH 61  661 519 HOH HOH C . 
M 5 HOH 62  662 280 HOH HOH C . 
M 5 HOH 63  663 108 HOH HOH C . 
M 5 HOH 64  664 166 HOH HOH C . 
M 5 HOH 65  665 449 HOH HOH C . 
M 5 HOH 66  666 170 HOH HOH C . 
M 5 HOH 67  667 121 HOH HOH C . 
M 5 HOH 68  668 340 HOH HOH C . 
M 5 HOH 69  669 596 HOH HOH C . 
M 5 HOH 70  670 357 HOH HOH C . 
M 5 HOH 71  671 493 HOH HOH C . 
M 5 HOH 72  672 314 HOH HOH C . 
M 5 HOH 73  673 199 HOH HOH C . 
M 5 HOH 74  674 360 HOH HOH C . 
M 5 HOH 75  675 94  HOH HOH C . 
M 5 HOH 76  676 124 HOH HOH C . 
M 5 HOH 77  677 272 HOH HOH C . 
M 5 HOH 78  678 520 HOH HOH C . 
M 5 HOH 79  679 65  HOH HOH C . 
M 5 HOH 80  680 98  HOH HOH C . 
M 5 HOH 81  681 140 HOH HOH C . 
M 5 HOH 82  682 598 HOH HOH C . 
M 5 HOH 83  683 561 HOH HOH C . 
M 5 HOH 84  684 270 HOH HOH C . 
M 5 HOH 85  685 105 HOH HOH C . 
M 5 HOH 86  686 508 HOH HOH C . 
M 5 HOH 87  687 462 HOH HOH C . 
M 5 HOH 88  688 119 HOH HOH C . 
M 5 HOH 89  689 369 HOH HOH C . 
M 5 HOH 90  690 299 HOH HOH C . 
M 5 HOH 91  691 353 HOH HOH C . 
M 5 HOH 92  692 79  HOH HOH C . 
M 5 HOH 93  693 495 HOH HOH C . 
M 5 HOH 94  694 525 HOH HOH C . 
M 5 HOH 95  695 459 HOH HOH C . 
M 5 HOH 96  696 206 HOH HOH C . 
M 5 HOH 97  697 464 HOH HOH C . 
M 5 HOH 98  698 27  HOH HOH C . 
M 5 HOH 99  699 125 HOH HOH C . 
M 5 HOH 100 700 560 HOH HOH C . 
M 5 HOH 101 701 455 HOH HOH C . 
M 5 HOH 102 702 237 HOH HOH C . 
M 5 HOH 103 703 444 HOH HOH C . 
M 5 HOH 104 704 41  HOH HOH C . 
M 5 HOH 105 705 261 HOH HOH C . 
M 5 HOH 106 706 200 HOH HOH C . 
M 5 HOH 107 707 169 HOH HOH C . 
M 5 HOH 108 708 463 HOH HOH C . 
M 5 HOH 109 709 201 HOH HOH C . 
M 5 HOH 110 710 35  HOH HOH C . 
M 5 HOH 111 711 66  HOH HOH C . 
M 5 HOH 112 712 234 HOH HOH C . 
M 5 HOH 113 713 339 HOH HOH C . 
M 5 HOH 114 714 89  HOH HOH C . 
M 5 HOH 115 715 17  HOH HOH C . 
M 5 HOH 116 716 39  HOH HOH C . 
M 5 HOH 117 717 555 HOH HOH C . 
M 5 HOH 118 718 135 HOH HOH C . 
M 5 HOH 119 719 29  HOH HOH C . 
M 5 HOH 120 720 97  HOH HOH C . 
M 5 HOH 121 721 381 HOH HOH C . 
M 5 HOH 122 722 162 HOH HOH C . 
M 5 HOH 123 723 186 HOH HOH C . 
M 5 HOH 124 724 114 HOH HOH C . 
M 5 HOH 125 725 457 HOH HOH C . 
M 5 HOH 126 726 286 HOH HOH C . 
M 5 HOH 127 727 122 HOH HOH C . 
M 5 HOH 128 728 15  HOH HOH C . 
M 5 HOH 129 729 149 HOH HOH C . 
M 5 HOH 130 730 542 HOH HOH C . 
M 5 HOH 131 731 595 HOH HOH C . 
M 5 HOH 132 732 418 HOH HOH C . 
M 5 HOH 133 733 407 HOH HOH C . 
M 5 HOH 134 734 496 HOH HOH C . 
M 5 HOH 135 735 73  HOH HOH C . 
M 5 HOH 136 736 321 HOH HOH C . 
M 5 HOH 137 737 30  HOH HOH C . 
M 5 HOH 138 738 564 HOH HOH C . 
M 5 HOH 139 739 192 HOH HOH C . 
M 5 HOH 140 740 133 HOH HOH C . 
M 5 HOH 141 741 358 HOH HOH C . 
M 5 HOH 142 742 103 HOH HOH C . 
M 5 HOH 143 743 189 HOH HOH C . 
M 5 HOH 144 744 131 HOH HOH C . 
M 5 HOH 145 745 263 HOH HOH C . 
M 5 HOH 146 746 205 HOH HOH C . 
M 5 HOH 147 747 70  HOH HOH C . 
M 5 HOH 148 748 197 HOH HOH C . 
M 5 HOH 149 749 506 HOH HOH C . 
M 5 HOH 150 750 377 HOH HOH C . 
M 5 HOH 151 751 18  HOH HOH C . 
M 5 HOH 152 752 246 HOH HOH C . 
M 5 HOH 153 753 290 HOH HOH C . 
M 5 HOH 154 754 548 HOH HOH C . 
M 5 HOH 155 755 412 HOH HOH C . 
M 5 HOH 156 756 52  HOH HOH C . 
M 5 HOH 157 757 327 HOH HOH C . 
M 5 HOH 158 758 393 HOH HOH C . 
M 5 HOH 159 759 557 HOH HOH C . 
M 5 HOH 160 760 256 HOH HOH C . 
M 5 HOH 161 761 90  HOH HOH C . 
M 5 HOH 162 762 487 HOH HOH C . 
M 5 HOH 163 763 365 HOH HOH C . 
M 5 HOH 164 764 78  HOH HOH C . 
M 5 HOH 165 765 485 HOH HOH C . 
M 5 HOH 166 766 396 HOH HOH C . 
M 5 HOH 167 767 60  HOH HOH C . 
M 5 HOH 168 768 9   HOH HOH C . 
M 5 HOH 169 769 219 HOH HOH C . 
M 5 HOH 170 770 372 HOH HOH C . 
M 5 HOH 171 771 288 HOH HOH C . 
M 5 HOH 172 772 379 HOH HOH C . 
M 5 HOH 173 773 478 HOH HOH C . 
M 5 HOH 174 774 134 HOH HOH C . 
M 5 HOH 175 775 171 HOH HOH C . 
M 5 HOH 176 776 415 HOH HOH C . 
M 5 HOH 177 777 513 HOH HOH C . 
M 5 HOH 178 778 356 HOH HOH C . 
M 5 HOH 179 779 230 HOH HOH C . 
M 5 HOH 180 780 64  HOH HOH C . 
M 5 HOH 181 781 216 HOH HOH C . 
M 5 HOH 182 782 21  HOH HOH C . 
M 5 HOH 183 783 602 HOH HOH C . 
M 5 HOH 184 784 599 HOH HOH C . 
M 5 HOH 185 785 31  HOH HOH C . 
M 5 HOH 186 786 92  HOH HOH C . 
M 5 HOH 187 787 268 HOH HOH C . 
M 5 HOH 188 788 19  HOH HOH C . 
M 5 HOH 189 789 262 HOH HOH C . 
M 5 HOH 190 790 427 HOH HOH C . 
M 5 HOH 191 791 531 HOH HOH C . 
M 5 HOH 192 792 466 HOH HOH C . 
M 5 HOH 193 793 330 HOH HOH C . 
M 5 HOH 194 794 354 HOH HOH C . 
M 5 HOH 195 795 483 HOH HOH C . 
M 5 HOH 196 796 388 HOH HOH C . 
M 5 HOH 197 797 367 HOH HOH C . 
M 5 HOH 198 798 440 HOH HOH C . 
M 5 HOH 199 799 404 HOH HOH C . 
M 5 HOH 200 800 177 HOH HOH C . 
M 5 HOH 201 801 414 HOH HOH C . 
M 5 HOH 202 802 251 HOH HOH C . 
M 5 HOH 203 803 480 HOH HOH C . 
M 5 HOH 204 804 159 HOH HOH C . 
M 5 HOH 205 805 178 HOH HOH C . 
M 5 HOH 206 806 336 HOH HOH C . 
M 5 HOH 207 807 435 HOH HOH C . 
M 5 HOH 208 808 419 HOH HOH C . 
M 5 HOH 209 809 502 HOH HOH C . 
M 5 HOH 210 810 586 HOH HOH C . 
M 5 HOH 211 811 231 HOH HOH C . 
M 5 HOH 212 812 323 HOH HOH C . 
M 5 HOH 213 813 465 HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 368 ? CG  ? A LYS 368 CG  
2  1 Y 1 A LYS 368 ? CD  ? A LYS 368 CD  
3  1 Y 1 A LYS 368 ? CE  ? A LYS 368 CE  
4  1 Y 1 A LYS 368 ? NZ  ? A LYS 368 NZ  
5  1 Y 1 A LYS 443 ? CG  ? A LYS 443 CG  
6  1 Y 1 A LYS 443 ? CD  ? A LYS 443 CD  
7  1 Y 1 A LYS 443 ? CE  ? A LYS 443 CE  
8  1 Y 1 A LYS 443 ? NZ  ? A LYS 443 NZ  
9  1 Y 1 A LEU 444 ? CG  ? A LEU 444 CG  
10 1 Y 1 A LEU 444 ? CD1 ? A LEU 444 CD1 
11 1 Y 1 A LEU 444 ? CD2 ? A LEU 444 CD2 
12 1 Y 1 A LEU 448 ? CG  ? A LEU 448 CG  
13 1 Y 1 A LEU 448 ? CD1 ? A LEU 448 CD1 
14 1 Y 1 A LEU 448 ? CD2 ? A LEU 448 CD2 
15 1 Y 1 B LYS 368 ? CG  ? B LYS 368 CG  
16 1 Y 1 B LYS 368 ? CD  ? B LYS 368 CD  
17 1 Y 1 B LYS 368 ? CE  ? B LYS 368 CE  
18 1 Y 1 B LYS 368 ? NZ  ? B LYS 368 NZ  
19 1 Y 1 B LYS 443 ? CG  ? B LYS 443 CG  
20 1 Y 1 B LYS 443 ? CD  ? B LYS 443 CD  
21 1 Y 1 B LYS 443 ? CE  ? B LYS 443 CE  
22 1 Y 1 B LYS 443 ? NZ  ? B LYS 443 NZ  
23 1 Y 1 B LEU 444 ? CG  ? B LEU 444 CG  
24 1 Y 1 B LEU 444 ? CD1 ? B LEU 444 CD1 
25 1 Y 1 B LEU 444 ? CD2 ? B LEU 444 CD2 
26 1 Y 1 B LEU 448 ? CG  ? B LEU 448 CG  
27 1 Y 1 B LEU 448 ? CD1 ? B LEU 448 CD1 
28 1 Y 1 B LEU 448 ? CD2 ? B LEU 448 CD2 
29 1 Y 1 B GLU 449 ? CG  ? B GLU 449 CG  
30 1 Y 1 B GLU 449 ? CD  ? B GLU 449 CD  
31 1 Y 1 B GLU 449 ? OE1 ? B GLU 449 OE1 
32 1 Y 1 B GLU 449 ? OE2 ? B GLU 449 OE2 
33 1 Y 1 C LYS 368 ? CG  ? C LYS 368 CG  
34 1 Y 1 C LYS 368 ? CD  ? C LYS 368 CD  
35 1 Y 1 C LYS 368 ? CE  ? C LYS 368 CE  
36 1 Y 1 C LYS 368 ? NZ  ? C LYS 368 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0411 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XXE 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     109.910 
_cell.length_a_esd                 ? 
_cell.length_b                     109.910 
_cell.length_b_esd                 ? 
_cell.length_c                     265.090 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XXE 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                96 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 43 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XXE 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.63 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          53.25 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1M BIS-TRIS pH 6.5, 2.4M Ammonium sulfate' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-01-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9792 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9792 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8XXE 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.08 
_reflns.d_resolution_low                               34.46 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     98252 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           100.0 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                25.7 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          19.3 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.189 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.181 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.08 
_reflns_shell.d_res_low                                     2.13 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             7160 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.363 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.896 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.313 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.00 
_refine.aniso_B[1][2]                            -0.00 
_refine.aniso_B[1][3]                            -0.00 
_refine.aniso_B[2][2]                            -0.00 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            0.00 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               39.132 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.965 
_refine.correlation_coeff_Fo_to_Fc_free          0.948 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8XXE 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.08 
_refine.ls_d_res_low                             34.46 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     93238 
_refine.ls_number_reflns_R_free                  4900 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.96 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.17326 
_refine.ls_R_factor_R_free                       0.21672 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.17098 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.178 
_refine.pdbx_overall_ESU_R_Free                  0.161 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             3.889 
_refine.overall_SU_ML                            0.106 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.08 
_refine_hist.d_res_low                        34.46 
_refine_hist.number_atoms_solvent             598 
_refine_hist.number_atoms_total               11466 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        10694 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         174 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  11180 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  10442 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.555  1.658  15177 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.480  1.570  24041 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.312  5.000  1340  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 7.435  5.000  90    ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 15.966 10.000 1843  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.070  0.200  1611  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.008  0.020  13001 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  2606  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 3.447  3.795  5365  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 3.447  3.796  5366  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 4.448  6.804  6702  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 4.448  6.804  6703  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 4.766  4.393  5815  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.766  4.394  5816  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.018  7.849  8476  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 8.057  38.40  13281 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 8.058  38.20  13172 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.080 
_refine_ls_shell.d_res_low                        2.134 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             335 
_refine_ls_shell.number_reflns_R_work             6791 
_refine_ls_shell.percent_reflns_obs               100.00 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.204 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.260 
# 
_struct.entry_id                     8XXE 
_struct.title                        'TtCS-intermediate complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XXE 
_struct_keywords.text            'citrate synthase, citrate cleavage, reversible, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 2 ? 
G N N 3 ? 
H N N 2 ? 
I N N 3 ? 
J N N 4 ? 
K N N 5 ? 
L N N 5 ? 
M N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CISY_THET7 
_struct_ref.pdbx_db_accession          A0A0S3QTD0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGS
;
_struct_ref.pdbx_align_begin           0 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XXE A 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
2 1 8XXE B 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
3 1 8XXE C 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XXE LYS A 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 1  
1 8XXE LEU A 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 2  
1 8XXE ALA A 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 3  
1 8XXE ALA A 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 4  
1 8XXE ALA A 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 5  
1 8XXE LEU A 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 6  
1 8XXE GLU A 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 7  
2 8XXE LYS B 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 8  
2 8XXE LEU B 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 9  
2 8XXE ALA B 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 10 
2 8XXE ALA B 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 11 
2 8XXE ALA B 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 12 
2 8XXE LEU B 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 13 
2 8XXE GLU B 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 14 
3 8XXE LYS C 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 15 
3 8XXE LEU C 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 16 
3 8XXE ALA C 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 17 
3 8XXE ALA C 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 18 
3 8XXE ALA C 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 19 
3 8XXE LEU C 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 20 
3 8XXE GLU C 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 21 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 12310 ? 
1 MORE         -56   ? 
1 'SSA (A^2)'  30980 ? 
2 'ABSA (A^2)' 12680 ? 
2 MORE         -57   ? 
2 'SSA (A^2)'  30060 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1   A,B,D,E,F,G,K,L 
2 1,2 C,H,I,J,M       
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z  1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 7_555 y,x,-z 0.0000000000 1.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 MET A 1   ? GLY A 26  ? MET A 1   GLY A 26  1 ? 26 
HELX_P HELX_P2  AA2 ILE A 35  ? GLY A 40  ? ILE A 35  GLY A 40  1 ? 6  
HELX_P HELX_P3  AA3 ILE A 68  ? GLU A 73  ? ILE A 68  GLU A 73  1 ? 6  
HELX_P HELX_P4  AA4 LEU A 88  ? GLY A 99  ? LEU A 88  GLY A 99  1 ? 12 
HELX_P HELX_P5  AA5 THR A 103 ? MET A 118 ? THR A 103 MET A 118 1 ? 16 
HELX_P HELX_P6  AA6 GLN A 119 ? VAL A 121 ? GLN A 119 VAL A 121 5 ? 3  
HELX_P HELX_P7  AA7 PRO A 122 ? MET A 132 ? PRO A 122 MET A 132 1 ? 11 
HELX_P HELX_P8  AA8 HIS A 137 ? MET A 149 ? HIS A 137 MET A 149 1 ? 13 
HELX_P HELX_P9  AA9 GLN A 150 ? GLU A 152 ? GLN A 150 GLU A 152 5 ? 3  
HELX_P HELX_P10 AB1 SER A 153 ? GLY A 162 ? SER A 153 GLY A 162 1 ? 10 
HELX_P HELX_P11 AB2 ARG A 164 ? GLU A 166 ? ARG A 164 GLU A 166 5 ? 3  
HELX_P HELX_P12 AB3 GLU A 167 ? LYS A 196 ? GLU A 167 LYS A 196 1 ? 30 
HELX_P HELX_P13 AB4 ASP A 208 ? GLY A 218 ? ASP A 208 GLY A 218 1 ? 11 
HELX_P HELX_P14 AB5 ASP A 221 ? HIS A 235 ? ASP A 221 HIS A 235 1 ? 15 
HELX_P HELX_P15 AB6 ASN A 242 ? ALA A 254 ? ASN A 242 ALA A 254 1 ? 13 
HELX_P HELX_P16 AB7 ASP A 257 ? ALA A 270 ? ASP A 257 ALA A 270 1 ? 14 
HELX_P HELX_P17 AB8 GLY A 271 ? LEU A 276 ? GLY A 271 LEU A 276 1 ? 6  
HELX_P HELX_P18 AB9 LEU A 276 ? PHE A 292 ? LEU A 276 PHE A 292 1 ? 17 
HELX_P HELX_P19 AC1 THR A 297 ? SER A 311 ? THR A 297 SER A 311 1 ? 15 
HELX_P HELX_P20 AC2 ASP A 327 ? LEU A 341 ? ASP A 327 LEU A 341 1 ? 15 
HELX_P HELX_P21 AC3 ASP A 344 ? GLY A 365 ? ASP A 344 GLY A 365 1 ? 22 
HELX_P HELX_P22 AC4 ASN A 373 ? ALA A 376 ? ASN A 373 ALA A 376 5 ? 4  
HELX_P HELX_P23 AC5 HIS A 377 ? TYR A 385 ? HIS A 377 TYR A 385 1 ? 9  
HELX_P HELX_P24 AC6 GLU A 389 ? ASP A 391 ? GLU A 389 ASP A 391 5 ? 3  
HELX_P HELX_P25 AC7 PHE A 392 ? MET A 416 ? PHE A 392 MET A 416 1 ? 25 
HELX_P HELX_P26 AC8 THR A 426 ? ALA A 434 ? THR A 426 ALA A 434 1 ? 9  
HELX_P HELX_P27 AC9 SER A 442 ? LEU A 448 ? SER A 442 LEU A 448 1 ? 7  
HELX_P HELX_P28 AD1 LYS B 2   ? GLY B 26  ? LYS B 2   GLY B 26  1 ? 25 
HELX_P HELX_P29 AD2 ILE B 35  ? GLY B 40  ? ILE B 35  GLY B 40  1 ? 6  
HELX_P HELX_P30 AD3 THR B 67  ? GLU B 73  ? THR B 67  GLU B 73  1 ? 7  
HELX_P HELX_P31 AD4 LEU B 88  ? GLY B 99  ? LEU B 88  GLY B 99  1 ? 12 
HELX_P HELX_P32 AD5 THR B 103 ? MET B 118 ? THR B 103 MET B 118 1 ? 16 
HELX_P HELX_P33 AD6 PRO B 122 ? MET B 132 ? PRO B 122 MET B 132 1 ? 11 
HELX_P HELX_P34 AD7 HIS B 137 ? MET B 149 ? HIS B 137 MET B 149 1 ? 13 
HELX_P HELX_P35 AD8 GLN B 150 ? GLU B 152 ? GLN B 150 GLU B 152 5 ? 3  
HELX_P HELX_P36 AD9 SER B 153 ? GLY B 162 ? SER B 153 GLY B 162 1 ? 10 
HELX_P HELX_P37 AE1 ARG B 164 ? GLU B 166 ? ARG B 164 GLU B 166 5 ? 3  
HELX_P HELX_P38 AE2 GLU B 167 ? LYS B 196 ? GLU B 167 LYS B 196 1 ? 30 
HELX_P HELX_P39 AE3 ASP B 208 ? GLY B 218 ? ASP B 208 GLY B 218 1 ? 11 
HELX_P HELX_P40 AE4 ASP B 221 ? HIS B 235 ? ASP B 221 HIS B 235 1 ? 15 
HELX_P HELX_P41 AE5 ASN B 242 ? ALA B 254 ? ASN B 242 ALA B 254 1 ? 13 
HELX_P HELX_P42 AE6 ASP B 257 ? ALA B 270 ? ASP B 257 ALA B 270 1 ? 14 
HELX_P HELX_P43 AE7 LEU B 276 ? PHE B 292 ? LEU B 276 PHE B 292 1 ? 17 
HELX_P HELX_P44 AE8 THR B 297 ? SER B 311 ? THR B 297 SER B 311 1 ? 15 
HELX_P HELX_P45 AE9 ASP B 327 ? LEU B 341 ? ASP B 327 LEU B 341 1 ? 15 
HELX_P HELX_P46 AF1 ASP B 344 ? GLY B 365 ? ASP B 344 GLY B 365 1 ? 22 
HELX_P HELX_P47 AF2 VAL B 374 ? TYR B 385 ? VAL B 374 TYR B 385 1 ? 12 
HELX_P HELX_P48 AF3 GLU B 389 ? ASP B 391 ? GLU B 389 ASP B 391 5 ? 3  
HELX_P HELX_P49 AF4 PHE B 392 ? MET B 416 ? PHE B 392 MET B 416 1 ? 25 
HELX_P HELX_P50 AF5 THR B 426 ? ALA B 434 ? THR B 426 ALA B 434 1 ? 9  
HELX_P HELX_P51 AF6 SER B 442 ? GLU B 449 ? SER B 442 GLU B 449 1 ? 8  
HELX_P HELX_P52 AF7 LYS C 2   ? GLY C 26  ? LYS C 2   GLY C 26  1 ? 25 
HELX_P HELX_P53 AF8 THR C 34  ? GLY C 40  ? THR C 34  GLY C 40  1 ? 7  
HELX_P HELX_P54 AF9 ILE C 68  ? GLU C 73  ? ILE C 68  GLU C 73  1 ? 6  
HELX_P HELX_P55 AG1 LEU C 88  ? GLY C 99  ? LEU C 88  GLY C 99  1 ? 12 
HELX_P HELX_P56 AG2 THR C 103 ? MET C 118 ? THR C 103 MET C 118 1 ? 16 
HELX_P HELX_P57 AG3 PRO C 122 ? MET C 132 ? PRO C 122 MET C 132 1 ? 11 
HELX_P HELX_P58 AG4 HIS C 137 ? MET C 149 ? HIS C 137 MET C 149 1 ? 13 
HELX_P HELX_P59 AG5 GLN C 150 ? GLU C 152 ? GLN C 150 GLU C 152 5 ? 3  
HELX_P HELX_P60 AG6 SER C 153 ? GLY C 162 ? SER C 153 GLY C 162 1 ? 10 
HELX_P HELX_P61 AG7 ARG C 164 ? GLU C 166 ? ARG C 164 GLU C 166 5 ? 3  
HELX_P HELX_P62 AG8 GLU C 167 ? LYS C 196 ? GLU C 167 LYS C 196 1 ? 30 
HELX_P HELX_P63 AG9 ASP C 208 ? GLY C 218 ? ASP C 208 GLY C 218 1 ? 11 
HELX_P HELX_P64 AH1 ASP C 221 ? HIS C 235 ? ASP C 221 HIS C 235 1 ? 15 
HELX_P HELX_P65 AH2 ASN C 242 ? SER C 253 ? ASN C 242 SER C 253 1 ? 12 
HELX_P HELX_P66 AH3 ASP C 257 ? ALA C 270 ? ASP C 257 ALA C 270 1 ? 14 
HELX_P HELX_P67 AH4 GLY C 271 ? LEU C 276 ? GLY C 271 LEU C 276 1 ? 6  
HELX_P HELX_P68 AH5 LEU C 276 ? GLY C 293 ? LEU C 276 GLY C 293 1 ? 18 
HELX_P HELX_P69 AH6 THR C 297 ? SER C 311 ? THR C 297 SER C 311 1 ? 15 
HELX_P HELX_P70 AH7 ASP C 327 ? LEU C 341 ? ASP C 327 LEU C 341 1 ? 15 
HELX_P HELX_P71 AH8 ASP C 344 ? GLY C 365 ? ASP C 344 GLY C 365 1 ? 22 
HELX_P HELX_P72 AH9 ASN C 373 ? ALA C 376 ? ASN C 373 ALA C 376 5 ? 4  
HELX_P HELX_P73 AI1 HIS C 377 ? TYR C 385 ? HIS C 377 TYR C 385 1 ? 9  
HELX_P HELX_P74 AI2 GLU C 389 ? ASP C 391 ? GLU C 389 ASP C 391 5 ? 3  
HELX_P HELX_P75 AI3 PHE C 392 ? MET C 416 ? PHE C 392 MET C 416 1 ? 25 
HELX_P HELX_P76 AI4 THR C 426 ? ALA C 434 ? THR C 426 ALA C 434 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? parallel      
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 29  ? THR A 34  ? LYS A 29  THR A 34  
AA1 2 LYS B 29  ? THR B 34  ? LYS B 29  THR B 34  
AA2 1 LYS A 46  ? VAL A 49  ? LYS A 46  VAL A 49  
AA2 2 LYS B 423 ? ILE B 425 ? LYS B 423 ILE B 425 
AA3 1 SER A 53  ? PHE A 56  ? SER A 53  PHE A 56  
AA3 2 GLY A 60  ? PHE A 63  ? GLY A 60  PHE A 63  
AA3 3 TYR A 66  ? THR A 67  ? TYR A 66  THR A 67  
AA4 1 LYS A 423 ? ILE A 425 ? LYS A 423 ILE A 425 
AA4 2 LYS B 46  ? VAL B 49  ? LYS B 46  VAL B 49  
AA5 1 SER B 53  ? PHE B 56  ? SER B 53  PHE B 56  
AA5 2 GLY B 60  ? PHE B 63  ? GLY B 60  PHE B 63  
AA6 1 SER C 53  ? PHE C 56  ? SER C 53  PHE C 56  
AA6 2 GLY C 60  ? PHE C 63  ? GLY C 60  PHE C 63  
AA6 3 TYR C 66  ? THR C 67  ? TYR C 66  THR C 67  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N CYS A 33  ? N CYS A 33  O MET B 31  ? O MET B 31  
AA2 1 2 N LEU A 48  ? N LEU A 48  O ILE B 425 ? O ILE B 425 
AA3 1 2 N PHE A 56  ? N PHE A 56  O GLY A 60  ? O GLY A 60  
AA3 2 3 N PHE A 63  ? N PHE A 63  O TYR A 66  ? O TYR A 66  
AA4 1 2 N ILE A 425 ? N ILE A 425 O LEU B 48  ? O LEU B 48  
AA5 1 2 N PHE B 56  ? N PHE B 56  O GLY B 60  ? O GLY B 60  
AA6 1 2 N PHE C 56  ? N PHE C 56  O GLY C 60  ? O GLY C 60  
AA6 2 3 N PHE C 63  ? N PHE C 63  O TYR C 66  ? O TYR C 66  
# 
_pdbx_entry_details.entry_id                   8XXE 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   B HOH 761 ? ? O B HOH 784 ? ? 1.63 
2 1 C   B GLU 449 ? ? O B HOH 604 ? ? 1.91 
3 1 O   B HOH 645 ? ? O B HOH 790 ? ? 2.04 
4 1 OE2 C GLU 299 ? ? O C HOH 601 ? ? 2.10 
5 1 O   A HOH 651 ? ? O A HOH 740 ? ? 2.10 
6 1 O   B HOH 625 ? ? O B HOH 774 ? ? 2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 59  ? ? -145.22 -14.15  
2  1 HIS A 238 ? ? -152.90 62.92   
3  1 GLU A 239 ? ? 68.96   -175.00 
4  1 VAL A 322 ? ? -149.84 -48.25  
5  1 LEU A 341 ? ? -144.55 55.91   
6  1 ARG A 421 ? ? -154.86 74.52   
7  1 GLU B 73  ? ? -140.09 -36.13  
8  1 HIS B 238 ? ? -154.32 67.00   
9  1 GLU B 239 ? ? 62.08   -175.77 
10 1 LEU B 341 ? ? -144.34 52.50   
11 1 ARG B 421 ? ? -153.34 78.37   
12 1 HIS C 238 ? ? -157.37 61.76   
13 1 GLU C 239 ? ? 70.31   -169.50 
14 1 VAL C 322 ? ? -135.20 -33.74  
15 1 LEU C 341 ? ? -144.53 53.67   
16 1 ARG C 421 ? ? -155.00 80.76   
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 GLU A 73  ? ? GLY A 74  ? ? -149.83 
2 1 HIS B 320 ? ? ALA B 321 ? ? -149.28 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 6   ? ? 0.082 'SIDE CHAIN' 
2 1 ARG A 43  ? ? 0.121 'SIDE CHAIN' 
3 1 ARG A 158 ? ? 0.101 'SIDE CHAIN' 
4 1 ARG A 324 ? ? 0.147 'SIDE CHAIN' 
5 1 ARG B 401 ? ? 0.073 'SIDE CHAIN' 
6 1 ARG C 6   ? ? 0.094 'SIDE CHAIN' 
# 
_pdbx_struct_special_symmetry.id              1 
_pdbx_struct_special_symmetry.PDB_model_num   1 
_pdbx_struct_special_symmetry.auth_asym_id    B 
_pdbx_struct_special_symmetry.auth_comp_id    HOH 
_pdbx_struct_special_symmetry.auth_seq_id     773 
_pdbx_struct_special_symmetry.PDB_ins_code    ? 
_pdbx_struct_special_symmetry.label_asym_id   L 
_pdbx_struct_special_symmetry.label_comp_id   HOH 
_pdbx_struct_special_symmetry.label_seq_id    . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLU 449 ? A GLU 449 
2 1 Y 1 C LYS 443 ? C LYS 443 
3 1 Y 1 C LEU 444 ? C LEU 444 
4 1 Y 1 C ALA 445 ? C ALA 445 
5 1 Y 1 C ALA 446 ? C ALA 446 
6 1 Y 1 C ALA 447 ? C ALA 447 
7 1 Y 1 C LEU 448 ? C LEU 448 
8 1 Y 1 C GLU 449 ? C GLU 449 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ACE C    C N N 1   
ACE O    O N N 2   
ACE CH3  C N N 3   
ACE H    H N N 4   
ACE H1   H N N 5   
ACE H2   H N N 6   
ACE H3   H N N 7   
ALA N    N N N 8   
ALA CA   C N S 9   
ALA C    C N N 10  
ALA O    O N N 11  
ALA CB   C N N 12  
ALA OXT  O N N 13  
ALA H    H N N 14  
ALA H2   H N N 15  
ALA HA   H N N 16  
ALA HB1  H N N 17  
ALA HB2  H N N 18  
ALA HB3  H N N 19  
ALA HXT  H N N 20  
ARG N    N N N 21  
ARG CA   C N S 22  
ARG C    C N N 23  
ARG O    O N N 24  
ARG CB   C N N 25  
ARG CG   C N N 26  
ARG CD   C N N 27  
ARG NE   N N N 28  
ARG CZ   C N N 29  
ARG NH1  N N N 30  
ARG NH2  N N N 31  
ARG OXT  O N N 32  
ARG H    H N N 33  
ARG H2   H N N 34  
ARG HA   H N N 35  
ARG HB2  H N N 36  
ARG HB3  H N N 37  
ARG HG2  H N N 38  
ARG HG3  H N N 39  
ARG HD2  H N N 40  
ARG HD3  H N N 41  
ARG HE   H N N 42  
ARG HH11 H N N 43  
ARG HH12 H N N 44  
ARG HH21 H N N 45  
ARG HH22 H N N 46  
ARG HXT  H N N 47  
ASN N    N N N 48  
ASN CA   C N S 49  
ASN C    C N N 50  
ASN O    O N N 51  
ASN CB   C N N 52  
ASN CG   C N N 53  
ASN OD1  O N N 54  
ASN ND2  N N N 55  
ASN OXT  O N N 56  
ASN H    H N N 57  
ASN H2   H N N 58  
ASN HA   H N N 59  
ASN HB2  H N N 60  
ASN HB3  H N N 61  
ASN HD21 H N N 62  
ASN HD22 H N N 63  
ASN HXT  H N N 64  
ASP N    N N N 65  
ASP CA   C N S 66  
ASP C    C N N 67  
ASP O    O N N 68  
ASP CB   C N N 69  
ASP CG   C N N 70  
ASP OD1  O N N 71  
ASP OD2  O N N 72  
ASP OXT  O N N 73  
ASP H    H N N 74  
ASP H2   H N N 75  
ASP HA   H N N 76  
ASP HB2  H N N 77  
ASP HB3  H N N 78  
ASP HD2  H N N 79  
ASP HXT  H N N 80  
COA N1A  N Y N 81  
COA C2A  C Y N 82  
COA N3A  N Y N 83  
COA C4A  C Y N 84  
COA C5A  C Y N 85  
COA C6A  C Y N 86  
COA N6A  N N N 87  
COA N7A  N Y N 88  
COA C8A  C Y N 89  
COA N9A  N Y N 90  
COA C1B  C N R 91  
COA C2B  C N R 92  
COA O2B  O N N 93  
COA C3B  C N S 94  
COA O3B  O N N 95  
COA P3B  P N N 96  
COA O7A  O N N 97  
COA O8A  O N N 98  
COA O9A  O N N 99  
COA C4B  C N R 100 
COA O4B  O N N 101 
COA C5B  C N N 102 
COA O5B  O N N 103 
COA P1A  P N S 104 
COA O1A  O N N 105 
COA O2A  O N N 106 
COA O3A  O N N 107 
COA P2A  P N S 108 
COA O4A  O N N 109 
COA O5A  O N N 110 
COA O6A  O N N 111 
COA CBP  C N N 112 
COA CCP  C N N 113 
COA CDP  C N N 114 
COA CEP  C N N 115 
COA CAP  C N R 116 
COA OAP  O N N 117 
COA C9P  C N N 118 
COA O9P  O N N 119 
COA N8P  N N N 120 
COA C7P  C N N 121 
COA C6P  C N N 122 
COA C5P  C N N 123 
COA O5P  O N N 124 
COA N4P  N N N 125 
COA C3P  C N N 126 
COA C2P  C N N 127 
COA S1P  S N N 128 
COA H2A  H N N 129 
COA H61A H N N 130 
COA H62A H N N 131 
COA H8A  H N N 132 
COA H1B  H N N 133 
COA H2B  H N N 134 
COA HO2A H N N 135 
COA H3B  H N N 136 
COA HOA8 H N N 137 
COA HOA9 H N N 138 
COA H4B  H N N 139 
COA H51A H N N 140 
COA H52A H N N 141 
COA HOA2 H N N 142 
COA HOA5 H N N 143 
COA H121 H N N 144 
COA H122 H N N 145 
COA H131 H N N 146 
COA H132 H N N 147 
COA H133 H N N 148 
COA H141 H N N 149 
COA H142 H N N 150 
COA H143 H N N 151 
COA H10  H N N 152 
COA HO1  H N N 153 
COA HN8  H N N 154 
COA H71  H N N 155 
COA H72  H N N 156 
COA H61  H N N 157 
COA H62  H N N 158 
COA HN4  H N N 159 
COA H31  H N N 160 
COA H32  H N N 161 
COA H21  H N N 162 
COA H22  H N N 163 
COA HS1  H N N 164 
CYS N    N N N 165 
CYS CA   C N R 166 
CYS C    C N N 167 
CYS O    O N N 168 
CYS CB   C N N 169 
CYS SG   S N N 170 
CYS OXT  O N N 171 
CYS H    H N N 172 
CYS H2   H N N 173 
CYS HA   H N N 174 
CYS HB2  H N N 175 
CYS HB3  H N N 176 
CYS HG   H N N 177 
CYS HXT  H N N 178 
GLN N    N N N 179 
GLN CA   C N S 180 
GLN C    C N N 181 
GLN O    O N N 182 
GLN CB   C N N 183 
GLN CG   C N N 184 
GLN CD   C N N 185 
GLN OE1  O N N 186 
GLN NE2  N N N 187 
GLN OXT  O N N 188 
GLN H    H N N 189 
GLN H2   H N N 190 
GLN HA   H N N 191 
GLN HB2  H N N 192 
GLN HB3  H N N 193 
GLN HG2  H N N 194 
GLN HG3  H N N 195 
GLN HE21 H N N 196 
GLN HE22 H N N 197 
GLN HXT  H N N 198 
GLU N    N N N 199 
GLU CA   C N S 200 
GLU C    C N N 201 
GLU O    O N N 202 
GLU CB   C N N 203 
GLU CG   C N N 204 
GLU CD   C N N 205 
GLU OE1  O N N 206 
GLU OE2  O N N 207 
GLU OXT  O N N 208 
GLU H    H N N 209 
GLU H2   H N N 210 
GLU HA   H N N 211 
GLU HB2  H N N 212 
GLU HB3  H N N 213 
GLU HG2  H N N 214 
GLU HG3  H N N 215 
GLU HE2  H N N 216 
GLU HXT  H N N 217 
GLY N    N N N 218 
GLY CA   C N N 219 
GLY C    C N N 220 
GLY O    O N N 221 
GLY OXT  O N N 222 
GLY H    H N N 223 
GLY H2   H N N 224 
GLY HA2  H N N 225 
GLY HA3  H N N 226 
GLY HXT  H N N 227 
HIS N    N N N 228 
HIS CA   C N S 229 
HIS C    C N N 230 
HIS O    O N N 231 
HIS CB   C N N 232 
HIS CG   C Y N 233 
HIS ND1  N Y N 234 
HIS CD2  C Y N 235 
HIS CE1  C Y N 236 
HIS NE2  N Y N 237 
HIS OXT  O N N 238 
HIS H    H N N 239 
HIS H2   H N N 240 
HIS HA   H N N 241 
HIS HB2  H N N 242 
HIS HB3  H N N 243 
HIS HD1  H N N 244 
HIS HD2  H N N 245 
HIS HE1  H N N 246 
HIS HE2  H N N 247 
HIS HXT  H N N 248 
HOH O    O N N 249 
HOH H1   H N N 250 
HOH H2   H N N 251 
ILE N    N N N 252 
ILE CA   C N S 253 
ILE C    C N N 254 
ILE O    O N N 255 
ILE CB   C N S 256 
ILE CG1  C N N 257 
ILE CG2  C N N 258 
ILE CD1  C N N 259 
ILE OXT  O N N 260 
ILE H    H N N 261 
ILE H2   H N N 262 
ILE HA   H N N 263 
ILE HB   H N N 264 
ILE HG12 H N N 265 
ILE HG13 H N N 266 
ILE HG21 H N N 267 
ILE HG22 H N N 268 
ILE HG23 H N N 269 
ILE HD11 H N N 270 
ILE HD12 H N N 271 
ILE HD13 H N N 272 
ILE HXT  H N N 273 
LEU N    N N N 274 
LEU CA   C N S 275 
LEU C    C N N 276 
LEU O    O N N 277 
LEU CB   C N N 278 
LEU CG   C N N 279 
LEU CD1  C N N 280 
LEU CD2  C N N 281 
LEU OXT  O N N 282 
LEU H    H N N 283 
LEU H2   H N N 284 
LEU HA   H N N 285 
LEU HB2  H N N 286 
LEU HB3  H N N 287 
LEU HG   H N N 288 
LEU HD11 H N N 289 
LEU HD12 H N N 290 
LEU HD13 H N N 291 
LEU HD21 H N N 292 
LEU HD22 H N N 293 
LEU HD23 H N N 294 
LEU HXT  H N N 295 
LYS N    N N N 296 
LYS CA   C N S 297 
LYS C    C N N 298 
LYS O    O N N 299 
LYS CB   C N N 300 
LYS CG   C N N 301 
LYS CD   C N N 302 
LYS CE   C N N 303 
LYS NZ   N N N 304 
LYS OXT  O N N 305 
LYS H    H N N 306 
LYS H2   H N N 307 
LYS HA   H N N 308 
LYS HB2  H N N 309 
LYS HB3  H N N 310 
LYS HG2  H N N 311 
LYS HG3  H N N 312 
LYS HD2  H N N 313 
LYS HD3  H N N 314 
LYS HE2  H N N 315 
LYS HE3  H N N 316 
LYS HZ1  H N N 317 
LYS HZ2  H N N 318 
LYS HZ3  H N N 319 
LYS HXT  H N N 320 
MET N    N N N 321 
MET CA   C N S 322 
MET C    C N N 323 
MET O    O N N 324 
MET CB   C N N 325 
MET CG   C N N 326 
MET SD   S N N 327 
MET CE   C N N 328 
MET OXT  O N N 329 
MET H    H N N 330 
MET H2   H N N 331 
MET HA   H N N 332 
MET HB2  H N N 333 
MET HB3  H N N 334 
MET HG2  H N N 335 
MET HG3  H N N 336 
MET HE1  H N N 337 
MET HE2  H N N 338 
MET HE3  H N N 339 
MET HXT  H N N 340 
OAA O1   O N N 341 
OAA O2   O N N 342 
OAA O4   O N N 343 
OAA O5   O N N 344 
OAA O3   O N N 345 
OAA C1   C N N 346 
OAA C2   C N N 347 
OAA C3   C N N 348 
OAA C4   C N N 349 
OAA HO5  H N N 350 
OAA H21  H N N 351 
OAA H22  H N N 352 
PHE N    N N N 353 
PHE CA   C N S 354 
PHE C    C N N 355 
PHE O    O N N 356 
PHE CB   C N N 357 
PHE CG   C Y N 358 
PHE CD1  C Y N 359 
PHE CD2  C Y N 360 
PHE CE1  C Y N 361 
PHE CE2  C Y N 362 
PHE CZ   C Y N 363 
PHE OXT  O N N 364 
PHE H    H N N 365 
PHE H2   H N N 366 
PHE HA   H N N 367 
PHE HB2  H N N 368 
PHE HB3  H N N 369 
PHE HD1  H N N 370 
PHE HD2  H N N 371 
PHE HE1  H N N 372 
PHE HE2  H N N 373 
PHE HZ   H N N 374 
PHE HXT  H N N 375 
PRO N    N N N 376 
PRO CA   C N S 377 
PRO C    C N N 378 
PRO O    O N N 379 
PRO CB   C N N 380 
PRO CG   C N N 381 
PRO CD   C N N 382 
PRO OXT  O N N 383 
PRO H    H N N 384 
PRO HA   H N N 385 
PRO HB2  H N N 386 
PRO HB3  H N N 387 
PRO HG2  H N N 388 
PRO HG3  H N N 389 
PRO HD2  H N N 390 
PRO HD3  H N N 391 
PRO HXT  H N N 392 
SER N    N N N 393 
SER CA   C N S 394 
SER C    C N N 395 
SER O    O N N 396 
SER CB   C N N 397 
SER OG   O N N 398 
SER OXT  O N N 399 
SER H    H N N 400 
SER H2   H N N 401 
SER HA   H N N 402 
SER HB2  H N N 403 
SER HB3  H N N 404 
SER HG   H N N 405 
SER HXT  H N N 406 
THR N    N N N 407 
THR CA   C N S 408 
THR C    C N N 409 
THR O    O N N 410 
THR CB   C N R 411 
THR OG1  O N N 412 
THR CG2  C N N 413 
THR OXT  O N N 414 
THR H    H N N 415 
THR H2   H N N 416 
THR HA   H N N 417 
THR HB   H N N 418 
THR HG1  H N N 419 
THR HG21 H N N 420 
THR HG22 H N N 421 
THR HG23 H N N 422 
THR HXT  H N N 423 
TRP N    N N N 424 
TRP CA   C N S 425 
TRP C    C N N 426 
TRP O    O N N 427 
TRP CB   C N N 428 
TRP CG   C Y N 429 
TRP CD1  C Y N 430 
TRP CD2  C Y N 431 
TRP NE1  N Y N 432 
TRP CE2  C Y N 433 
TRP CE3  C Y N 434 
TRP CZ2  C Y N 435 
TRP CZ3  C Y N 436 
TRP CH2  C Y N 437 
TRP OXT  O N N 438 
TRP H    H N N 439 
TRP H2   H N N 440 
TRP HA   H N N 441 
TRP HB2  H N N 442 
TRP HB3  H N N 443 
TRP HD1  H N N 444 
TRP HE1  H N N 445 
TRP HE3  H N N 446 
TRP HZ2  H N N 447 
TRP HZ3  H N N 448 
TRP HH2  H N N 449 
TRP HXT  H N N 450 
TYR N    N N N 451 
TYR CA   C N S 452 
TYR C    C N N 453 
TYR O    O N N 454 
TYR CB   C N N 455 
TYR CG   C Y N 456 
TYR CD1  C Y N 457 
TYR CD2  C Y N 458 
TYR CE1  C Y N 459 
TYR CE2  C Y N 460 
TYR CZ   C Y N 461 
TYR OH   O N N 462 
TYR OXT  O N N 463 
TYR H    H N N 464 
TYR H2   H N N 465 
TYR HA   H N N 466 
TYR HB2  H N N 467 
TYR HB3  H N N 468 
TYR HD1  H N N 469 
TYR HD2  H N N 470 
TYR HE1  H N N 471 
TYR HE2  H N N 472 
TYR HH   H N N 473 
TYR HXT  H N N 474 
VAL N    N N N 475 
VAL CA   C N S 476 
VAL C    C N N 477 
VAL O    O N N 478 
VAL CB   C N N 479 
VAL CG1  C N N 480 
VAL CG2  C N N 481 
VAL OXT  O N N 482 
VAL H    H N N 483 
VAL H2   H N N 484 
VAL HA   H N N 485 
VAL HB   H N N 486 
VAL HG11 H N N 487 
VAL HG12 H N N 488 
VAL HG13 H N N 489 
VAL HG21 H N N 490 
VAL HG22 H N N 491 
VAL HG23 H N N 492 
VAL HXT  H N N 493 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ACE C   O    doub N N 1   
ACE C   CH3  sing N N 2   
ACE C   H    sing N N 3   
ACE CH3 H1   sing N N 4   
ACE CH3 H2   sing N N 5   
ACE CH3 H3   sing N N 6   
ALA N   CA   sing N N 7   
ALA N   H    sing N N 8   
ALA N   H2   sing N N 9   
ALA CA  C    sing N N 10  
ALA CA  CB   sing N N 11  
ALA CA  HA   sing N N 12  
ALA C   O    doub N N 13  
ALA C   OXT  sing N N 14  
ALA CB  HB1  sing N N 15  
ALA CB  HB2  sing N N 16  
ALA CB  HB3  sing N N 17  
ALA OXT HXT  sing N N 18  
ARG N   CA   sing N N 19  
ARG N   H    sing N N 20  
ARG N   H2   sing N N 21  
ARG CA  C    sing N N 22  
ARG CA  CB   sing N N 23  
ARG CA  HA   sing N N 24  
ARG C   O    doub N N 25  
ARG C   OXT  sing N N 26  
ARG CB  CG   sing N N 27  
ARG CB  HB2  sing N N 28  
ARG CB  HB3  sing N N 29  
ARG CG  CD   sing N N 30  
ARG CG  HG2  sing N N 31  
ARG CG  HG3  sing N N 32  
ARG CD  NE   sing N N 33  
ARG CD  HD2  sing N N 34  
ARG CD  HD3  sing N N 35  
ARG NE  CZ   sing N N 36  
ARG NE  HE   sing N N 37  
ARG CZ  NH1  sing N N 38  
ARG CZ  NH2  doub N N 39  
ARG NH1 HH11 sing N N 40  
ARG NH1 HH12 sing N N 41  
ARG NH2 HH21 sing N N 42  
ARG NH2 HH22 sing N N 43  
ARG OXT HXT  sing N N 44  
ASN N   CA   sing N N 45  
ASN N   H    sing N N 46  
ASN N   H2   sing N N 47  
ASN CA  C    sing N N 48  
ASN CA  CB   sing N N 49  
ASN CA  HA   sing N N 50  
ASN C   O    doub N N 51  
ASN C   OXT  sing N N 52  
ASN CB  CG   sing N N 53  
ASN CB  HB2  sing N N 54  
ASN CB  HB3  sing N N 55  
ASN CG  OD1  doub N N 56  
ASN CG  ND2  sing N N 57  
ASN ND2 HD21 sing N N 58  
ASN ND2 HD22 sing N N 59  
ASN OXT HXT  sing N N 60  
ASP N   CA   sing N N 61  
ASP N   H    sing N N 62  
ASP N   H2   sing N N 63  
ASP CA  C    sing N N 64  
ASP CA  CB   sing N N 65  
ASP CA  HA   sing N N 66  
ASP C   O    doub N N 67  
ASP C   OXT  sing N N 68  
ASP CB  CG   sing N N 69  
ASP CB  HB2  sing N N 70  
ASP CB  HB3  sing N N 71  
ASP CG  OD1  doub N N 72  
ASP CG  OD2  sing N N 73  
ASP OD2 HD2  sing N N 74  
ASP OXT HXT  sing N N 75  
COA N1A C2A  sing Y N 76  
COA N1A C6A  doub Y N 77  
COA C2A N3A  doub Y N 78  
COA C2A H2A  sing N N 79  
COA N3A C4A  sing Y N 80  
COA C4A C5A  doub Y N 81  
COA C4A N9A  sing Y N 82  
COA C5A C6A  sing Y N 83  
COA C5A N7A  sing Y N 84  
COA C6A N6A  sing N N 85  
COA N6A H61A sing N N 86  
COA N6A H62A sing N N 87  
COA N7A C8A  doub Y N 88  
COA C8A N9A  sing Y N 89  
COA C8A H8A  sing N N 90  
COA N9A C1B  sing N N 91  
COA C1B C2B  sing N N 92  
COA C1B O4B  sing N N 93  
COA C1B H1B  sing N N 94  
COA C2B O2B  sing N N 95  
COA C2B C3B  sing N N 96  
COA C2B H2B  sing N N 97  
COA O2B HO2A sing N N 98  
COA C3B O3B  sing N N 99  
COA C3B C4B  sing N N 100 
COA C3B H3B  sing N N 101 
COA O3B P3B  sing N N 102 
COA P3B O7A  doub N N 103 
COA P3B O8A  sing N N 104 
COA P3B O9A  sing N N 105 
COA O8A HOA8 sing N N 106 
COA O9A HOA9 sing N N 107 
COA C4B O4B  sing N N 108 
COA C4B C5B  sing N N 109 
COA C4B H4B  sing N N 110 
COA C5B O5B  sing N N 111 
COA C5B H51A sing N N 112 
COA C5B H52A sing N N 113 
COA O5B P1A  sing N N 114 
COA P1A O1A  doub N N 115 
COA P1A O2A  sing N N 116 
COA P1A O3A  sing N N 117 
COA O2A HOA2 sing N N 118 
COA O3A P2A  sing N N 119 
COA P2A O4A  doub N N 120 
COA P2A O5A  sing N N 121 
COA P2A O6A  sing N N 122 
COA O5A HOA5 sing N N 123 
COA O6A CCP  sing N N 124 
COA CBP CCP  sing N N 125 
COA CBP CDP  sing N N 126 
COA CBP CEP  sing N N 127 
COA CBP CAP  sing N N 128 
COA CCP H121 sing N N 129 
COA CCP H122 sing N N 130 
COA CDP H131 sing N N 131 
COA CDP H132 sing N N 132 
COA CDP H133 sing N N 133 
COA CEP H141 sing N N 134 
COA CEP H142 sing N N 135 
COA CEP H143 sing N N 136 
COA CAP OAP  sing N N 137 
COA CAP C9P  sing N N 138 
COA CAP H10  sing N N 139 
COA OAP HO1  sing N N 140 
COA C9P O9P  doub N N 141 
COA C9P N8P  sing N N 142 
COA N8P C7P  sing N N 143 
COA N8P HN8  sing N N 144 
COA C7P C6P  sing N N 145 
COA C7P H71  sing N N 146 
COA C7P H72  sing N N 147 
COA C6P C5P  sing N N 148 
COA C6P H61  sing N N 149 
COA C6P H62  sing N N 150 
COA C5P O5P  doub N N 151 
COA C5P N4P  sing N N 152 
COA N4P C3P  sing N N 153 
COA N4P HN4  sing N N 154 
COA C3P C2P  sing N N 155 
COA C3P H31  sing N N 156 
COA C3P H32  sing N N 157 
COA C2P S1P  sing N N 158 
COA C2P H21  sing N N 159 
COA C2P H22  sing N N 160 
COA S1P HS1  sing N N 161 
CYS N   CA   sing N N 162 
CYS N   H    sing N N 163 
CYS N   H2   sing N N 164 
CYS CA  C    sing N N 165 
CYS CA  CB   sing N N 166 
CYS CA  HA   sing N N 167 
CYS C   O    doub N N 168 
CYS C   OXT  sing N N 169 
CYS CB  SG   sing N N 170 
CYS CB  HB2  sing N N 171 
CYS CB  HB3  sing N N 172 
CYS SG  HG   sing N N 173 
CYS OXT HXT  sing N N 174 
GLN N   CA   sing N N 175 
GLN N   H    sing N N 176 
GLN N   H2   sing N N 177 
GLN CA  C    sing N N 178 
GLN CA  CB   sing N N 179 
GLN CA  HA   sing N N 180 
GLN C   O    doub N N 181 
GLN C   OXT  sing N N 182 
GLN CB  CG   sing N N 183 
GLN CB  HB2  sing N N 184 
GLN CB  HB3  sing N N 185 
GLN CG  CD   sing N N 186 
GLN CG  HG2  sing N N 187 
GLN CG  HG3  sing N N 188 
GLN CD  OE1  doub N N 189 
GLN CD  NE2  sing N N 190 
GLN NE2 HE21 sing N N 191 
GLN NE2 HE22 sing N N 192 
GLN OXT HXT  sing N N 193 
GLU N   CA   sing N N 194 
GLU N   H    sing N N 195 
GLU N   H2   sing N N 196 
GLU CA  C    sing N N 197 
GLU CA  CB   sing N N 198 
GLU CA  HA   sing N N 199 
GLU C   O    doub N N 200 
GLU C   OXT  sing N N 201 
GLU CB  CG   sing N N 202 
GLU CB  HB2  sing N N 203 
GLU CB  HB3  sing N N 204 
GLU CG  CD   sing N N 205 
GLU CG  HG2  sing N N 206 
GLU CG  HG3  sing N N 207 
GLU CD  OE1  doub N N 208 
GLU CD  OE2  sing N N 209 
GLU OE2 HE2  sing N N 210 
GLU OXT HXT  sing N N 211 
GLY N   CA   sing N N 212 
GLY N   H    sing N N 213 
GLY N   H2   sing N N 214 
GLY CA  C    sing N N 215 
GLY CA  HA2  sing N N 216 
GLY CA  HA3  sing N N 217 
GLY C   O    doub N N 218 
GLY C   OXT  sing N N 219 
GLY OXT HXT  sing N N 220 
HIS N   CA   sing N N 221 
HIS N   H    sing N N 222 
HIS N   H2   sing N N 223 
HIS CA  C    sing N N 224 
HIS CA  CB   sing N N 225 
HIS CA  HA   sing N N 226 
HIS C   O    doub N N 227 
HIS C   OXT  sing N N 228 
HIS CB  CG   sing N N 229 
HIS CB  HB2  sing N N 230 
HIS CB  HB3  sing N N 231 
HIS CG  ND1  sing Y N 232 
HIS CG  CD2  doub Y N 233 
HIS ND1 CE1  doub Y N 234 
HIS ND1 HD1  sing N N 235 
HIS CD2 NE2  sing Y N 236 
HIS CD2 HD2  sing N N 237 
HIS CE1 NE2  sing Y N 238 
HIS CE1 HE1  sing N N 239 
HIS NE2 HE2  sing N N 240 
HIS OXT HXT  sing N N 241 
HOH O   H1   sing N N 242 
HOH O   H2   sing N N 243 
ILE N   CA   sing N N 244 
ILE N   H    sing N N 245 
ILE N   H2   sing N N 246 
ILE CA  C    sing N N 247 
ILE CA  CB   sing N N 248 
ILE CA  HA   sing N N 249 
ILE C   O    doub N N 250 
ILE C   OXT  sing N N 251 
ILE CB  CG1  sing N N 252 
ILE CB  CG2  sing N N 253 
ILE CB  HB   sing N N 254 
ILE CG1 CD1  sing N N 255 
ILE CG1 HG12 sing N N 256 
ILE CG1 HG13 sing N N 257 
ILE CG2 HG21 sing N N 258 
ILE CG2 HG22 sing N N 259 
ILE CG2 HG23 sing N N 260 
ILE CD1 HD11 sing N N 261 
ILE CD1 HD12 sing N N 262 
ILE CD1 HD13 sing N N 263 
ILE OXT HXT  sing N N 264 
LEU N   CA   sing N N 265 
LEU N   H    sing N N 266 
LEU N   H2   sing N N 267 
LEU CA  C    sing N N 268 
LEU CA  CB   sing N N 269 
LEU CA  HA   sing N N 270 
LEU C   O    doub N N 271 
LEU C   OXT  sing N N 272 
LEU CB  CG   sing N N 273 
LEU CB  HB2  sing N N 274 
LEU CB  HB3  sing N N 275 
LEU CG  CD1  sing N N 276 
LEU CG  CD2  sing N N 277 
LEU CG  HG   sing N N 278 
LEU CD1 HD11 sing N N 279 
LEU CD1 HD12 sing N N 280 
LEU CD1 HD13 sing N N 281 
LEU CD2 HD21 sing N N 282 
LEU CD2 HD22 sing N N 283 
LEU CD2 HD23 sing N N 284 
LEU OXT HXT  sing N N 285 
LYS N   CA   sing N N 286 
LYS N   H    sing N N 287 
LYS N   H2   sing N N 288 
LYS CA  C    sing N N 289 
LYS CA  CB   sing N N 290 
LYS CA  HA   sing N N 291 
LYS C   O    doub N N 292 
LYS C   OXT  sing N N 293 
LYS CB  CG   sing N N 294 
LYS CB  HB2  sing N N 295 
LYS CB  HB3  sing N N 296 
LYS CG  CD   sing N N 297 
LYS CG  HG2  sing N N 298 
LYS CG  HG3  sing N N 299 
LYS CD  CE   sing N N 300 
LYS CD  HD2  sing N N 301 
LYS CD  HD3  sing N N 302 
LYS CE  NZ   sing N N 303 
LYS CE  HE2  sing N N 304 
LYS CE  HE3  sing N N 305 
LYS NZ  HZ1  sing N N 306 
LYS NZ  HZ2  sing N N 307 
LYS NZ  HZ3  sing N N 308 
LYS OXT HXT  sing N N 309 
MET N   CA   sing N N 310 
MET N   H    sing N N 311 
MET N   H2   sing N N 312 
MET CA  C    sing N N 313 
MET CA  CB   sing N N 314 
MET CA  HA   sing N N 315 
MET C   O    doub N N 316 
MET C   OXT  sing N N 317 
MET CB  CG   sing N N 318 
MET CB  HB2  sing N N 319 
MET CB  HB3  sing N N 320 
MET CG  SD   sing N N 321 
MET CG  HG2  sing N N 322 
MET CG  HG3  sing N N 323 
MET SD  CE   sing N N 324 
MET CE  HE1  sing N N 325 
MET CE  HE2  sing N N 326 
MET CE  HE3  sing N N 327 
MET OXT HXT  sing N N 328 
OAA O1  C1   doub N N 329 
OAA O2  C1   sing N N 330 
OAA O4  C4   doub N N 331 
OAA O5  C4   sing N N 332 
OAA O5  HO5  sing N N 333 
OAA O3  C3   doub N N 334 
OAA C1  C2   sing N N 335 
OAA C2  C3   sing N N 336 
OAA C2  H21  sing N N 337 
OAA C2  H22  sing N N 338 
OAA C3  C4   sing N N 339 
PHE N   CA   sing N N 340 
PHE N   H    sing N N 341 
PHE N   H2   sing N N 342 
PHE CA  C    sing N N 343 
PHE CA  CB   sing N N 344 
PHE CA  HA   sing N N 345 
PHE C   O    doub N N 346 
PHE C   OXT  sing N N 347 
PHE CB  CG   sing N N 348 
PHE CB  HB2  sing N N 349 
PHE CB  HB3  sing N N 350 
PHE CG  CD1  doub Y N 351 
PHE CG  CD2  sing Y N 352 
PHE CD1 CE1  sing Y N 353 
PHE CD1 HD1  sing N N 354 
PHE CD2 CE2  doub Y N 355 
PHE CD2 HD2  sing N N 356 
PHE CE1 CZ   doub Y N 357 
PHE CE1 HE1  sing N N 358 
PHE CE2 CZ   sing Y N 359 
PHE CE2 HE2  sing N N 360 
PHE CZ  HZ   sing N N 361 
PHE OXT HXT  sing N N 362 
PRO N   CA   sing N N 363 
PRO N   CD   sing N N 364 
PRO N   H    sing N N 365 
PRO CA  C    sing N N 366 
PRO CA  CB   sing N N 367 
PRO CA  HA   sing N N 368 
PRO C   O    doub N N 369 
PRO C   OXT  sing N N 370 
PRO CB  CG   sing N N 371 
PRO CB  HB2  sing N N 372 
PRO CB  HB3  sing N N 373 
PRO CG  CD   sing N N 374 
PRO CG  HG2  sing N N 375 
PRO CG  HG3  sing N N 376 
PRO CD  HD2  sing N N 377 
PRO CD  HD3  sing N N 378 
PRO OXT HXT  sing N N 379 
SER N   CA   sing N N 380 
SER N   H    sing N N 381 
SER N   H2   sing N N 382 
SER CA  C    sing N N 383 
SER CA  CB   sing N N 384 
SER CA  HA   sing N N 385 
SER C   O    doub N N 386 
SER C   OXT  sing N N 387 
SER CB  OG   sing N N 388 
SER CB  HB2  sing N N 389 
SER CB  HB3  sing N N 390 
SER OG  HG   sing N N 391 
SER OXT HXT  sing N N 392 
THR N   CA   sing N N 393 
THR N   H    sing N N 394 
THR N   H2   sing N N 395 
THR CA  C    sing N N 396 
THR CA  CB   sing N N 397 
THR CA  HA   sing N N 398 
THR C   O    doub N N 399 
THR C   OXT  sing N N 400 
THR CB  OG1  sing N N 401 
THR CB  CG2  sing N N 402 
THR CB  HB   sing N N 403 
THR OG1 HG1  sing N N 404 
THR CG2 HG21 sing N N 405 
THR CG2 HG22 sing N N 406 
THR CG2 HG23 sing N N 407 
THR OXT HXT  sing N N 408 
TRP N   CA   sing N N 409 
TRP N   H    sing N N 410 
TRP N   H2   sing N N 411 
TRP CA  C    sing N N 412 
TRP CA  CB   sing N N 413 
TRP CA  HA   sing N N 414 
TRP C   O    doub N N 415 
TRP C   OXT  sing N N 416 
TRP CB  CG   sing N N 417 
TRP CB  HB2  sing N N 418 
TRP CB  HB3  sing N N 419 
TRP CG  CD1  doub Y N 420 
TRP CG  CD2  sing Y N 421 
TRP CD1 NE1  sing Y N 422 
TRP CD1 HD1  sing N N 423 
TRP CD2 CE2  doub Y N 424 
TRP CD2 CE3  sing Y N 425 
TRP NE1 CE2  sing Y N 426 
TRP NE1 HE1  sing N N 427 
TRP CE2 CZ2  sing Y N 428 
TRP CE3 CZ3  doub Y N 429 
TRP CE3 HE3  sing N N 430 
TRP CZ2 CH2  doub Y N 431 
TRP CZ2 HZ2  sing N N 432 
TRP CZ3 CH2  sing Y N 433 
TRP CZ3 HZ3  sing N N 434 
TRP CH2 HH2  sing N N 435 
TRP OXT HXT  sing N N 436 
TYR N   CA   sing N N 437 
TYR N   H    sing N N 438 
TYR N   H2   sing N N 439 
TYR CA  C    sing N N 440 
TYR CA  CB   sing N N 441 
TYR CA  HA   sing N N 442 
TYR C   O    doub N N 443 
TYR C   OXT  sing N N 444 
TYR CB  CG   sing N N 445 
TYR CB  HB2  sing N N 446 
TYR CB  HB3  sing N N 447 
TYR CG  CD1  doub Y N 448 
TYR CG  CD2  sing Y N 449 
TYR CD1 CE1  sing Y N 450 
TYR CD1 HD1  sing N N 451 
TYR CD2 CE2  doub Y N 452 
TYR CD2 HD2  sing N N 453 
TYR CE1 CZ   doub Y N 454 
TYR CE1 HE1  sing N N 455 
TYR CE2 CZ   sing Y N 456 
TYR CE2 HE2  sing N N 457 
TYR CZ  OH   sing N N 458 
TYR OH  HH   sing N N 459 
TYR OXT HXT  sing N N 460 
VAL N   CA   sing N N 461 
VAL N   H    sing N N 462 
VAL N   H2   sing N N 463 
VAL CA  C    sing N N 464 
VAL CA  CB   sing N N 465 
VAL CA  HA   sing N N 466 
VAL C   O    doub N N 467 
VAL C   OXT  sing N N 468 
VAL CB  CG1  sing N N 469 
VAL CB  CG2  sing N N 470 
VAL CB  HB   sing N N 471 
VAL CG1 HG11 sing N N 472 
VAL CG1 HG12 sing N N 473 
VAL CG1 HG13 sing N N 474 
VAL CG2 HG21 sing N N 475 
VAL CG2 HG22 sing N N 476 
VAL CG2 HG23 sing N N 477 
VAL OXT HXT  sing N N 478 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   A0A0S3QTD0 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8XXE 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009098 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009098 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.003772 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . MET A 1 1   ? -36.561 -16.511 -28.904 1.00 62.32  ? 1   MET A N   1 
ATOM   2     C CA  . MET A 1 1   ? -35.404 -16.316 -29.817 1.00 58.16  ? 1   MET A CA  1 
ATOM   3     C C   . MET A 1 1   ? -35.583 -17.249 -31.016 1.00 54.25  ? 1   MET A C   1 
ATOM   4     O O   . MET A 1 1   ? -35.838 -18.442 -30.841 1.00 61.21  ? 1   MET A O   1 
ATOM   5     C CB  . MET A 1 1   ? -34.101 -16.617 -29.058 1.00 60.32  ? 1   MET A CB  1 
ATOM   6     C CG  . MET A 1 1   ? -32.850 -16.675 -29.914 1.00 64.80  ? 1   MET A CG  1 
ATOM   7     S SD  . MET A 1 1   ? -31.310 -16.700 -28.910 1.00 67.88  ? 1   MET A SD  1 
ATOM   8     C CE  . MET A 1 1   ? -31.714 -18.011 -27.752 1.00 71.41  ? 1   MET A CE  1 
ATOM   9     N N   . LYS A 1 2   ? -35.502 -16.693 -32.232 1.00 53.14  ? 2   LYS A N   1 
ATOM   10    C CA  . LYS A 1 2   ? -35.661 -17.473 -33.450 1.00 55.21  ? 2   LYS A CA  1 
ATOM   11    C C   . LYS A 1 2   ? -34.702 -18.671 -33.434 1.00 56.20  ? 2   LYS A C   1 
ATOM   12    O O   . LYS A 1 2   ? -35.086 -19.796 -33.777 1.00 47.20  ? 2   LYS A O   1 
ATOM   13    C CB  . LYS A 1 2   ? -35.416 -16.565 -34.658 1.00 63.51  ? 2   LYS A CB  1 
ATOM   14    C CG  . LYS A 1 2   ? -35.390 -17.255 -36.015 1.00 73.32  ? 2   LYS A CG  1 
ATOM   15    C CD  . LYS A 1 2   ? -36.720 -17.829 -36.449 1.00 78.26  ? 2   LYS A CD  1 
ATOM   16    C CE  . LYS A 1 2   ? -36.631 -18.437 -37.830 1.00 80.54  ? 2   LYS A CE  1 
ATOM   17    N NZ  . LYS A 1 2   ? -37.958 -18.865 -38.324 1.00 84.98  ? 2   LYS A NZ  1 
ATOM   18    N N   . LEU A 1 3   ? -33.440 -18.417 -33.048 1.00 48.22  ? 3   LEU A N   1 
ATOM   19    C CA  . LEU A 1 3   ? -32.423 -19.455 -32.985 1.00 46.49  ? 3   LEU A CA  1 
ATOM   20    C C   . LEU A 1 3   ? -32.972 -20.679 -32.266 1.00 40.22  ? 3   LEU A C   1 
ATOM   21    O O   . LEU A 1 3   ? -32.851 -21.813 -32.735 1.00 43.24  ? 3   LEU A O   1 
ATOM   22    C CB  . LEU A 1 3   ? -31.169 -18.933 -32.273 1.00 46.29  ? 3   LEU A CB  1 
ATOM   23    C CG  . LEU A 1 3   ? -30.080 -19.985 -32.061 1.00 49.41  ? 3   LEU A CG  1 
ATOM   24    C CD1 . LEU A 1 3   ? -29.611 -20.543 -33.399 1.00 45.43  ? 3   LEU A CD1 1 
ATOM   25    C CD2 . LEU A 1 3   ? -28.907 -19.409 -31.279 1.00 47.95  ? 3   LEU A CD2 1 
ATOM   26    N N   . LYS A 1 4   ? -33.558 -20.449 -31.103 1.00 38.31  ? 4   LYS A N   1 
ATOM   27    C CA  . LYS A 1 4   ? -33.898 -21.559 -30.239 1.00 43.89  ? 4   LYS A CA  1 
ATOM   28    C C   . LYS A 1 4   ? -35.130 -22.303 -30.760 1.00 49.59  ? 4   LYS A C   1 
ATOM   29    O O   . LYS A 1 4   ? -35.246 -23.513 -30.570 1.00 44.57  ? 4   LYS A O   1 
ATOM   30    C CB  . LYS A 1 4   ? -34.152 -21.084 -28.812 1.00 42.72  ? 4   LYS A CB  1 
ATOM   31    C CG  . LYS A 1 4   ? -34.479 -22.262 -27.927 1.00 48.33  ? 4   LYS A CG  1 
ATOM   32    C CD  . LYS A 1 4   ? -34.609 -21.979 -26.497 1.00 51.37  ? 4   LYS A CD  1 
ATOM   33    C CE  . LYS A 1 4   ? -34.986 -23.262 -25.804 1.00 50.41  ? 4   LYS A CE  1 
ATOM   34    N NZ  . LYS A 1 4   ? -35.065 -23.045 -24.351 1.00 52.73  ? 4   LYS A NZ  1 
ATOM   35    N N   . GLU A 1 5   ? -36.066 -21.562 -31.370 1.00 46.52  ? 5   GLU A N   1 
ATOM   36    C CA  . GLU A 1 5   ? -37.257 -22.160 -31.964 1.00 50.84  ? 5   GLU A CA  1 
ATOM   37    C C   . GLU A 1 5   ? -36.857 -23.081 -33.109 1.00 45.43  ? 5   GLU A C   1 
ATOM   38    O O   . GLU A 1 5   ? -37.387 -24.170 -33.271 1.00 49.18  ? 5   GLU A O   1 
ATOM   39    C CB  . GLU A 1 5   ? -38.154 -21.081 -32.575 1.00 53.78  ? 5   GLU A CB  1 
ATOM   40    C CG  . GLU A 1 5   ? -38.775 -20.136 -31.565 1.00 57.17  ? 5   GLU A CG  1 
ATOM   41    C CD  . GLU A 1 5   ? -39.710 -19.123 -32.211 1.00 62.97  ? 5   GLU A CD  1 
ATOM   42    O OE1 . GLU A 1 5   ? -40.227 -18.271 -31.478 1.00 56.97  ? 5   GLU A OE1 1 
ATOM   43    O OE2 . GLU A 1 5   ? -39.929 -19.204 -33.448 1.00 67.87  ? 5   GLU A OE2 1 
ATOM   44    N N   . ARG A 1 6   ? -35.915 -22.595 -33.916 1.00 42.45  ? 6   ARG A N   1 
ATOM   45    C CA  . ARG A 1 6   ? -35.367 -23.340 -35.032 1.00 41.33  ? 6   ARG A CA  1 
ATOM   46    C C   . ARG A 1 6   ? -34.688 -24.612 -34.528 1.00 41.88  ? 6   ARG A C   1 
ATOM   47    O O   . ARG A 1 6   ? -34.899 -25.675 -35.102 1.00 41.46  ? 6   ARG A O   1 
ATOM   48    C CB  . ARG A 1 6   ? -34.398 -22.415 -35.766 1.00 45.82  ? 6   ARG A CB  1 
ATOM   49    C CG  . ARG A 1 6   ? -34.290 -22.667 -37.252 1.00 55.66  ? 6   ARG A CG  1 
ATOM   50    C CD  . ARG A 1 6   ? -35.618 -22.423 -37.948 1.00 55.64  ? 6   ARG A CD  1 
ATOM   51    N NE  . ARG A 1 6   ? -35.644 -23.396 -39.017 1.00 50.11  ? 6   ARG A NE  1 
ATOM   52    C CZ  . ARG A 1 6   ? -36.348 -24.509 -38.999 1.00 47.79  ? 6   ARG A CZ  1 
ATOM   53    N NH1 . ARG A 1 6   ? -37.369 -24.649 -38.173 1.00 52.85  ? 6   ARG A NH1 1 
ATOM   54    N NH2 . ARG A 1 6   ? -36.050 -25.454 -39.862 1.00 43.67  ? 6   ARG A NH2 1 
ATOM   55    N N   . LEU A 1 7   ? -33.896 -24.516 -33.438 1.00 41.16  ? 7   LEU A N   1 
ATOM   56    C CA  . LEU A 1 7   ? -33.206 -25.693 -32.905 1.00 42.86  ? 7   LEU A CA  1 
ATOM   57    C C   . LEU A 1 7   ? -34.234 -26.661 -32.316 1.00 34.70  ? 7   LEU A C   1 
ATOM   58    O O   . LEU A 1 7   ? -34.050 -27.878 -32.322 1.00 35.83  ? 7   LEU A O   1 
ATOM   59    C CB  . LEU A 1 7   ? -32.156 -25.288 -31.851 1.00 38.84  ? 7   LEU A CB  1 
ATOM   60    C CG  . LEU A 1 7   ? -30.884 -24.627 -32.392 1.00 39.14  ? 7   LEU A CG  1 
ATOM   61    C CD1 . LEU A 1 7   ? -29.978 -24.184 -31.244 1.00 37.39  ? 7   LEU A CD1 1 
ATOM   62    C CD2 . LEU A 1 7   ? -30.132 -25.542 -33.346 1.00 33.39  ? 7   LEU A CD2 1 
ATOM   63    N N   . ALA A 1 8   ? -35.300 -26.110 -31.751 1.00 35.13  ? 8   ALA A N   1 
ATOM   64    C CA  . ALA A 1 8   ? -36.295 -26.929 -31.083 1.00 39.93  ? 8   ALA A CA  1 
ATOM   65    C C   . ALA A 1 8   ? -36.991 -27.846 -32.101 1.00 40.14  ? 8   ALA A C   1 
ATOM   66    O O   . ALA A 1 8   ? -37.474 -28.905 -31.727 1.00 41.74  ? 8   ALA A O   1 
ATOM   67    C CB  . ALA A 1 8   ? -37.269 -26.049 -30.334 1.00 45.43  ? 8   ALA A CB  1 
ATOM   68    N N   . GLU A 1 9   ? -36.940 -27.495 -33.391 1.00 39.94  ? 9   GLU A N   1 
ATOM   69    C CA  . GLU A 1 9   ? -37.408 -28.369 -34.465 1.00 47.71  ? 9   GLU A CA  1 
ATOM   70    C C   . GLU A 1 9   ? -36.292 -29.197 -35.093 1.00 43.24  ? 9   GLU A C   1 
ATOM   71    O O   . GLU A 1 9   ? -36.494 -30.355 -35.426 1.00 47.10  ? 9   GLU A O   1 
ATOM   72    C CB  . GLU A 1 9   ? -38.012 -27.550 -35.600 1.00 53.60  ? 9   GLU A CB  1 
ATOM   73    C CG  . GLU A 1 9   ? -39.174 -26.700 -35.136 1.00 65.35  ? 9   GLU A CG  1 
ATOM   74    C CD  . GLU A 1 9   ? -40.013 -26.178 -36.285 1.00 80.70  ? 9   GLU A CD  1 
ATOM   75    O OE1 . GLU A 1 9   ? -40.087 -24.930 -36.437 1.00 82.43  ? 9   GLU A OE1 1 
ATOM   76    O OE2 . GLU A 1 9   ? -40.569 -27.027 -37.043 1.00 83.20  ? 9   GLU A OE2 1 
ATOM   77    N N   . LEU A 1 10  ? -35.127 -28.599 -35.331 1.00 39.35  ? 10  LEU A N   1 
ATOM   78    C CA  . LEU A 1 10  ? -34.110 -29.286 -36.108 1.00 36.83  ? 10  LEU A CA  1 
ATOM   79    C C   . LEU A 1 10  ? -33.444 -30.378 -35.269 1.00 41.42  ? 10  LEU A C   1 
ATOM   80    O O   . LEU A 1 10  ? -33.108 -31.442 -35.791 1.00 36.83  ? 10  LEU A O   1 
ATOM   81    C CB  . LEU A 1 10  ? -33.093 -28.285 -36.654 1.00 40.93  ? 10  LEU A CB  1 
ATOM   82    C CG  . LEU A 1 10  ? -33.543 -27.438 -37.843 1.00 43.63  ? 10  LEU A CG  1 
ATOM   83    C CD1 . LEU A 1 10  ? -32.698 -26.178 -37.973 1.00 41.16  ? 10  LEU A CD1 1 
ATOM   84    C CD2 . LEU A 1 10  ? -33.477 -28.244 -39.137 1.00 47.72  ? 10  LEU A CD2 1 
ATOM   85    N N   . ILE A 1 11  ? -33.278 -30.147 -33.963 1.00 40.31  ? 11  ILE A N   1 
ATOM   86    C CA  . ILE A 1 11  ? -32.461 -31.064 -33.170 1.00 40.72  ? 11  ILE A CA  1 
ATOM   87    C C   . ILE A 1 11  ? -33.160 -32.415 -33.020 1.00 40.59  ? 11  ILE A C   1 
ATOM   88    O O   . ILE A 1 11  ? -32.517 -33.446 -33.204 1.00 40.47  ? 11  ILE A O   1 
ATOM   89    C CB  . ILE A 1 11  ? -32.044 -30.447 -31.818 1.00 38.62  ? 11  ILE A CB  1 
ATOM   90    C CG1 . ILE A 1 11  ? -30.838 -29.520 -32.011 1.00 40.22  ? 11  ILE A CG1 1 
ATOM   91    C CG2 . ILE A 1 11  ? -31.748 -31.521 -30.788 1.00 38.42  ? 11  ILE A CG2 1 
ATOM   92    C CD1 . ILE A 1 11  ? -30.439 -28.789 -30.752 1.00 41.97  ? 11  ILE A CD1 1 
ATOM   93    N N   . PRO A 1 12  ? -34.473 -32.475 -32.692 1.00 43.80  ? 12  PRO A N   1 
ATOM   94    C CA  . PRO A 1 12  ? -35.206 -33.748 -32.663 1.00 46.79  ? 12  PRO A CA  1 
ATOM   95    C C   . PRO A 1 12  ? -35.083 -34.596 -33.932 1.00 43.14  ? 12  PRO A C   1 
ATOM   96    O O   . PRO A 1 12  ? -34.961 -35.817 -33.854 1.00 51.66  ? 12  PRO A O   1 
ATOM   97    C CB  . PRO A 1 12  ? -36.672 -33.325 -32.464 1.00 52.25  ? 12  PRO A CB  1 
ATOM   98    C CG  . PRO A 1 12  ? -36.579 -31.966 -31.784 1.00 49.80  ? 12  PRO A CG  1 
ATOM   99    C CD  . PRO A 1 12  ? -35.320 -31.328 -32.340 1.00 45.67  ? 12  PRO A CD  1 
ATOM   100   N N   . GLN A 1 13  ? -35.050 -33.941 -35.096 1.00 40.99  ? 13  GLN A N   1 
ATOM   101   C CA  . GLN A 1 13  ? -34.866 -34.621 -36.371 1.00 44.16  ? 13  GLN A CA  1 
ATOM   102   C C   . GLN A 1 13  ? -33.451 -35.164 -36.495 1.00 47.36  ? 13  GLN A C   1 
ATOM   103   O O   . GLN A 1 13  ? -33.240 -36.283 -36.957 1.00 44.36  ? 13  GLN A O   1 
ATOM   104   C CB  . GLN A 1 13  ? -35.039 -33.670 -37.562 1.00 49.74  ? 13  GLN A CB  1 
ATOM   105   C CG  . GLN A 1 13  ? -36.477 -33.298 -37.867 1.00 59.94  ? 13  GLN A CG  1 
ATOM   106   C CD  . GLN A 1 13  ? -36.529 -32.174 -38.872 1.00 65.74  ? 13  GLN A CD  1 
ATOM   107   O OE1 . GLN A 1 13  ? -35.764 -32.143 -39.838 1.00 66.22  ? 13  GLN A OE1 1 
ATOM   108   N NE2 . GLN A 1 13  ? -37.406 -31.217 -38.618 1.00 64.45  ? 13  GLN A NE2 1 
ATOM   109   N N   . TRP A 1 14  ? -32.471 -34.304 -36.187 1.00 44.39  ? 14  TRP A N   1 
ATOM   110   C CA  . TRP A 1 14  ? -31.073 -34.689 -36.292 1.00 40.88  ? 14  TRP A CA  1 
ATOM   111   C C   . TRP A 1 14  ? -30.782 -35.839 -35.341 1.00 34.84  ? 14  TRP A C   1 
ATOM   112   O O   . TRP A 1 14  ? -30.074 -36.779 -35.672 1.00 39.23  ? 14  TRP A O   1 
ATOM   113   C CB  . TRP A 1 14  ? -30.164 -33.490 -35.988 1.00 43.92  ? 14  TRP A CB  1 
ATOM   114   C CG  . TRP A 1 14  ? -30.156 -32.439 -37.044 1.00 44.02  ? 14  TRP A CG  1 
ATOM   115   C CD1 . TRP A 1 14  ? -30.406 -32.593 -38.380 1.00 44.10  ? 14  TRP A CD1 1 
ATOM   116   C CD2 . TRP A 1 14  ? -29.840 -31.050 -36.845 1.00 45.78  ? 14  TRP A CD2 1 
ATOM   117   N NE1 . TRP A 1 14  ? -30.276 -31.390 -39.017 1.00 41.80  ? 14  TRP A NE1 1 
ATOM   118   C CE2 . TRP A 1 14  ? -29.928 -30.427 -38.107 1.00 43.13  ? 14  TRP A CE2 1 
ATOM   119   C CE3 . TRP A 1 14  ? -29.490 -30.280 -35.725 1.00 49.51  ? 14  TRP A CE3 1 
ATOM   120   C CZ2 . TRP A 1 14  ? -29.675 -29.069 -38.280 1.00 40.98  ? 14  TRP A CZ2 1 
ATOM   121   C CZ3 . TRP A 1 14  ? -29.223 -28.937 -35.901 1.00 43.23  ? 14  TRP A CZ3 1 
ATOM   122   C CH2 . TRP A 1 14  ? -29.315 -28.347 -37.162 1.00 41.13  ? 14  TRP A CH2 1 
ATOM   123   N N   . ARG A 1 15  ? -31.327 -35.762 -34.140 1.00 39.16  ? 15  ARG A N   1 
ATOM   124   C CA  . ARG A 1 15  ? -31.140 -36.840 -33.191 1.00 38.53  ? 15  ARG A CA  1 
ATOM   125   C C   . ARG A 1 15  ? -31.649 -38.172 -33.746 1.00 42.76  ? 15  ARG A C   1 
ATOM   126   O O   . ARG A 1 15  ? -30.989 -39.207 -33.589 1.00 40.67  ? 15  ARG A O   1 
ATOM   127   C CB  . ARG A 1 15  ? -31.904 -36.532 -31.924 1.00 35.20  ? 15  ARG A CB  1 
ATOM   128   C CG  . ARG A 1 15  ? -31.694 -37.578 -30.847 1.00 43.62  ? 15  ARG A CG  1 
ATOM   129   C CD  . ARG A 1 15  ? -32.679 -37.347 -29.728 1.00 53.98  ? 15  ARG A CD  1 
ATOM   130   N NE  . ARG A 1 15  ? -32.748 -38.501 -28.841 1.00 60.43  ? 15  ARG A NE  1 
ATOM   131   C CZ  . ARG A 1 15  ? -33.789 -38.790 -28.070 1.00 69.73  ? 15  ARG A CZ  1 
ATOM   132   N NH1 . ARG A 1 15  ? -34.911 -38.095 -28.181 1.00 74.70  ? 15  ARG A NH1 1 
ATOM   133   N NH2 . ARG A 1 15  ? -33.710 -39.785 -27.204 1.00 75.13  ? 15  ARG A NH2 1 
ATOM   134   N N   . ALA A 1 16  ? -32.846 -38.134 -34.344 1.00 43.62  ? 16  ALA A N   1 
ATOM   135   C CA  . ALA A 1 16  ? -33.462 -39.328 -34.924 1.00 45.96  ? 16  ALA A CA  1 
ATOM   136   C C   . ALA A 1 16  ? -32.594 -39.826 -36.071 1.00 38.45  ? 16  ALA A C   1 
ATOM   137   O O   . ALA A 1 16  ? -32.339 -41.007 -36.177 1.00 44.77  ? 16  ALA A O   1 
ATOM   138   C CB  . ALA A 1 16  ? -34.881 -39.053 -35.393 1.00 44.46  ? 16  ALA A CB  1 
ATOM   139   N N   . GLU A 1 17  ? -32.096 -38.905 -36.898 1.00 43.39  ? 17  GLU A N   1 
ATOM   140   C CA  . GLU A 1 17  ? -31.308 -39.263 -38.067 1.00 45.70  ? 17  GLU A CA  1 
ATOM   141   C C   . GLU A 1 17  ? -29.993 -39.908 -37.650 1.00 48.25  ? 17  GLU A C   1 
ATOM   142   O O   . GLU A 1 17  ? -29.447 -40.753 -38.362 1.00 42.49  ? 17  GLU A O   1 
ATOM   143   C CB  . GLU A 1 17  ? -31.018 -38.003 -38.874 1.00 55.72  ? 17  GLU A CB  1 
ATOM   144   C CG  . GLU A 1 17  ? -30.835 -38.243 -40.352 1.00 71.32  ? 17  GLU A CG  1 
ATOM   145   C CD  . GLU A 1 17  ? -30.595 -36.944 -41.099 1.00 76.90  ? 17  GLU A CD  1 
ATOM   146   O OE1 . GLU A 1 17  ? -29.424 -36.544 -41.216 1.00 89.31  ? 17  GLU A OE1 1 
ATOM   147   O OE2 . GLU A 1 17  ? -31.587 -36.302 -41.487 1.00 83.99  ? 17  GLU A OE2 1 
ATOM   148   N N   . VAL A 1 18  ? -29.456 -39.468 -36.503 1.00 43.37  ? 18  VAL A N   1 
ATOM   149   C CA  . VAL A 1 18  ? -28.157 -39.953 -36.076 1.00 40.31  ? 18  VAL A CA  1 
ATOM   150   C C   . VAL A 1 18  ? -28.343 -41.353 -35.500 1.00 35.76  ? 18  VAL A C   1 
ATOM   151   O O   . VAL A 1 18  ? -27.511 -42.213 -35.740 1.00 35.15  ? 18  VAL A O   1 
ATOM   152   C CB  . VAL A 1 18  ? -27.464 -38.981 -35.091 1.00 40.12  ? 18  VAL A CB  1 
ATOM   153   C CG1 . VAL A 1 18  ? -26.381 -39.655 -34.259 1.00 39.83  ? 18  VAL A CG1 1 
ATOM   154   C CG2 . VAL A 1 18  ? -26.890 -37.776 -35.824 1.00 38.11  ? 18  VAL A CG2 1 
ATOM   155   N N   . ALA A 1 19  ? -29.403 -41.561 -34.715 1.00 39.04  ? 19  ALA A N   1 
ATOM   156   C CA  . ALA A 1 19  ? -29.722 -42.885 -34.200 1.00 44.29  ? 19  ALA A CA  1 
ATOM   157   C C   . ALA A 1 19  ? -29.906 -43.871 -35.355 1.00 45.55  ? 19  ALA A C   1 
ATOM   158   O O   . ALA A 1 19  ? -29.432 -45.006 -35.280 1.00 45.31  ? 19  ALA A O   1 
ATOM   159   C CB  . ALA A 1 19  ? -30.961 -42.825 -33.339 1.00 45.83  ? 19  ALA A CB  1 
ATOM   160   N N   . GLU A 1 20  ? -30.533 -43.405 -36.446 1.00 50.74  ? 20  GLU A N   1 
ATOM   161   C CA  . GLU A 1 20  ? -30.772 -44.243 -37.620 1.00 52.34  ? 20  GLU A CA  1 
ATOM   162   C C   . GLU A 1 20  ? -29.436 -44.640 -38.232 1.00 45.38  ? 20  GLU A C   1 
ATOM   163   O O   . GLU A 1 20  ? -29.179 -45.823 -38.418 1.00 49.77  ? 20  GLU A O   1 
ATOM   164   C CB  . GLU A 1 20  ? -31.716 -43.544 -38.605 1.00 59.04  ? 20  GLU A CB  1 
ATOM   165   C CG  . GLU A 1 20  ? -31.568 -43.981 -40.058 1.00 73.25  ? 20  GLU A CG  1 
ATOM   166   C CD  . GLU A 1 20  ? -32.283 -45.264 -40.444 1.00 80.39  ? 20  GLU A CD  1 
ATOM   167   O OE1 . GLU A 1 20  ? -31.916 -46.340 -39.912 1.00 67.59  ? 20  GLU A OE1 1 
ATOM   168   O OE2 . GLU A 1 20  ? -33.198 -45.181 -41.293 1.00 94.36  ? 20  GLU A OE2 1 
ATOM   169   N N   . ILE A 1 21  ? -28.567 -43.654 -38.490 1.00 48.08  ? 21  ILE A N   1 
ATOM   170   C CA  . ILE A 1 21  ? -27.239 -43.875 -39.048 1.00 45.89  ? 21  ILE A CA  1 
ATOM   171   C C   . ILE A 1 21  ? -26.414 -44.826 -38.181 1.00 44.90  ? 21  ILE A C   1 
ATOM   172   O O   . ILE A 1 21  ? -25.678 -45.642 -38.707 1.00 41.91  ? 21  ILE A O   1 
ATOM   173   C CB  . ILE A 1 21  ? -26.519 -42.526 -39.239 1.00 57.79  ? 21  ILE A CB  1 
ATOM   174   C CG1 . ILE A 1 21  ? -27.134 -41.738 -40.393 1.00 60.32  ? 21  ILE A CG1 1 
ATOM   175   C CG2 . ILE A 1 21  ? -25.018 -42.708 -39.410 1.00 54.77  ? 21  ILE A CG2 1 
ATOM   176   C CD1 . ILE A 1 21  ? -26.919 -40.250 -40.294 1.00 66.26  ? 21  ILE A CD1 1 
ATOM   177   N N   . ARG A 1 22  ? -26.522 -44.733 -36.851 1.00 43.72  ? 22  ARG A N   1 
ATOM   178   C CA  . ARG A 1 22  ? -25.730 -45.591 -35.986 1.00 46.81  ? 22  ARG A CA  1 
ATOM   179   C C   . ARG A 1 22  ? -26.227 -47.042 -36.064 1.00 46.91  ? 22  ARG A C   1 
ATOM   180   O O   . ARG A 1 22  ? -25.415 -47.961 -36.036 1.00 47.53  ? 22  ARG A O   1 
ATOM   181   C CB  . ARG A 1 22  ? -25.734 -45.062 -34.542 1.00 42.85  ? 22  ARG A CB  1 
ATOM   182   C CG  . ARG A 1 22  ? -25.037 -43.711 -34.387 1.00 43.18  ? 22  ARG A CG  1 
ATOM   183   C CD  . ARG A 1 22  ? -25.009 -43.217 -32.955 1.00 43.18  ? 22  ARG A CD  1 
ATOM   184   N NE  . ARG A 1 22  ? -24.237 -44.063 -32.067 1.00 47.32  ? 22  ARG A NE  1 
ATOM   185   C CZ  . ARG A 1 22  ? -24.372 -44.056 -30.751 1.00 45.85  ? 22  ARG A CZ  1 
ATOM   186   N NH1 . ARG A 1 22  ? -25.330 -43.336 -30.203 1.00 49.96  ? 22  ARG A NH1 1 
ATOM   187   N NH2 . ARG A 1 22  ? -23.565 -44.765 -29.987 1.00 42.62  ? 22  ARG A NH2 1 
ATOM   188   N N   . LYS A 1 23  ? -27.553 -47.238 -36.065 1.00 47.51  ? 23  LYS A N   1 
ATOM   189   C CA  . LYS A 1 23  ? -28.153 -48.557 -36.207 1.00 49.60  ? 23  LYS A CA  1 
ATOM   190   C C   . LYS A 1 23  ? -27.830 -49.116 -37.595 1.00 47.69  ? 23  LYS A C   1 
ATOM   191   O O   . LYS A 1 23  ? -27.183 -50.148 -37.735 1.00 47.18  ? 23  LYS A O   1 
ATOM   192   C CB  . LYS A 1 23  ? -29.663 -48.444 -35.994 1.00 54.83  ? 23  LYS A CB  1 
ATOM   193   C CG  . LYS A 1 23  ? -30.395 -49.754 -35.758 1.00 65.16  ? 23  LYS A CG  1 
ATOM   194   C CD  . LYS A 1 23  ? -31.750 -49.553 -35.094 1.00 78.99  ? 23  LYS A CD  1 
ATOM   195   C CE  . LYS A 1 23  ? -31.967 -50.460 -33.896 1.00 85.32  ? 23  LYS A CE  1 
ATOM   196   N NZ  . LYS A 1 23  ? -32.923 -49.868 -32.931 1.00 87.36  ? 23  LYS A NZ  1 
ATOM   197   N N   . LYS A 1 24  ? -28.208 -48.379 -38.638 1.00 49.67  ? 24  LYS A N   1 
ATOM   198   C CA  . LYS A 1 24  ? -28.101 -48.891 -39.993 1.00 50.51  ? 24  LYS A CA  1 
ATOM   199   C C   . LYS A 1 24  ? -26.653 -49.043 -40.469 1.00 50.86  ? 24  LYS A C   1 
ATOM   200   O O   . LYS A 1 24  ? -26.359 -50.019 -41.147 1.00 47.45  ? 24  LYS A O   1 
ATOM   201   C CB  . LYS A 1 24  ? -28.912 -48.013 -40.947 1.00 53.66  ? 24  LYS A CB  1 
ATOM   202   C CG  . LYS A 1 24  ? -28.700 -48.329 -42.420 1.00 62.26  ? 24  LYS A CG  1 
ATOM   203   C CD  . LYS A 1 24  ? -29.584 -47.531 -43.351 1.00 65.92  ? 24  LYS A CD  1 
ATOM   204   C CE  . LYS A 1 24  ? -31.031 -47.961 -43.327 1.00 71.51  ? 24  LYS A CE  1 
ATOM   205   N NZ  . LYS A 1 24  ? -31.631 -47.818 -44.675 1.00 80.74  ? 24  LYS A NZ  1 
ATOM   206   N N   . TYR A 1 25  ? -25.750 -48.088 -40.180 1.00 51.69  ? 25  TYR A N   1 
ATOM   207   C CA  . TYR A 1 25  ? -24.451 -48.026 -40.860 1.00 46.51  ? 25  TYR A CA  1 
ATOM   208   C C   . TYR A 1 25  ? -23.245 -48.075 -39.908 1.00 44.13  ? 25  TYR A C   1 
ATOM   209   O O   . TYR A 1 25  ? -22.091 -47.868 -40.328 1.00 42.12  ? 25  TYR A O   1 
ATOM   210   C CB  . TYR A 1 25  ? -24.346 -46.737 -41.672 1.00 47.63  ? 25  TYR A CB  1 
ATOM   211   C CG  . TYR A 1 25  ? -25.300 -46.610 -42.830 1.00 55.36  ? 25  TYR A CG  1 
ATOM   212   C CD1 . TYR A 1 25  ? -25.250 -47.500 -43.890 1.00 60.31  ? 25  TYR A CD1 1 
ATOM   213   C CD2 . TYR A 1 25  ? -26.233 -45.584 -42.890 1.00 57.07  ? 25  TYR A CD2 1 
ATOM   214   C CE1 . TYR A 1 25  ? -26.096 -47.371 -44.982 1.00 57.44  ? 25  TYR A CE1 1 
ATOM   215   C CE2 . TYR A 1 25  ? -27.093 -45.442 -43.968 1.00 55.82  ? 25  TYR A CE2 1 
ATOM   216   C CZ  . TYR A 1 25  ? -27.023 -46.344 -45.019 1.00 65.10  ? 25  TYR A CZ  1 
ATOM   217   O OH  . TYR A 1 25  ? -27.871 -46.250 -46.099 1.00 74.59  ? 25  TYR A OH  1 
ATOM   218   N N   . GLY A 1 26  ? -23.483 -48.396 -38.638 1.00 49.69  ? 26  GLY A N   1 
ATOM   219   C CA  . GLY A 1 26  ? -22.423 -48.353 -37.637 1.00 49.10  ? 26  GLY A CA  1 
ATOM   220   C C   . GLY A 1 26  ? -21.233 -49.224 -38.016 1.00 48.68  ? 26  GLY A C   1 
ATOM   221   O O   . GLY A 1 26  ? -20.086 -48.900 -37.718 1.00 40.42  ? 26  GLY A O   1 
ATOM   222   N N   . ASN A 1 27  ? -21.516 -50.349 -38.685 1.00 45.65  ? 27  ASN A N   1 
ATOM   223   C CA  . ASN A 1 27  ? -20.505 -51.361 -38.952 1.00 48.99  ? 27  ASN A CA  1 
ATOM   224   C C   . ASN A 1 27  ? -19.784 -51.090 -40.269 1.00 43.93  ? 27  ASN A C   1 
ATOM   225   O O   . ASN A 1 27  ? -18.901 -51.841 -40.669 1.00 47.34  ? 27  ASN A O   1 
ATOM   226   C CB  . ASN A 1 27  ? -21.127 -52.765 -38.928 1.00 55.90  ? 27  ASN A CB  1 
ATOM   227   C CG  . ASN A 1 27  ? -22.241 -52.947 -39.943 1.00 59.80  ? 27  ASN A CG  1 
ATOM   228   O OD1 . ASN A 1 27  ? -22.264 -52.313 -41.003 1.00 60.94  ? 27  ASN A OD1 1 
ATOM   229   N ND2 . ASN A 1 27  ? -23.156 -53.848 -39.640 1.00 63.08  ? 27  ASN A ND2 1 
ATOM   230   N N   . ARG A 1 28  ? -20.150 -50.017 -40.965 1.00 40.84  ? 28  ARG A N   1 
ATOM   231   C CA  . ARG A 1 28  ? -19.478 -49.690 -42.210 1.00 43.65  ? 28  ARG A CA  1 
ATOM   232   C C   . ARG A 1 28  ? -18.062 -49.221 -41.924 1.00 44.09  ? 28  ARG A C   1 
ATOM   233   O O   . ARG A 1 28  ? -17.846 -48.386 -41.053 1.00 36.47  ? 28  ARG A O   1 
ATOM   234   C CB  . ARG A 1 28  ? -20.235 -48.588 -42.961 1.00 47.00  ? 28  ARG A CB  1 
ATOM   235   C CG  . ARG A 1 28  ? -21.595 -49.026 -43.488 1.00 55.24  ? 28  ARG A CG  1 
ATOM   236   C CD  . ARG A 1 28  ? -21.411 -49.963 -44.674 1.00 55.39  ? 28  ARG A CD  1 
ATOM   237   N NE  . ARG A 1 28  ? -22.642 -50.235 -45.409 1.00 64.86  ? 28  ARG A NE  1 
ATOM   238   C CZ  . ARG A 1 28  ? -23.725 -50.782 -44.879 1.00 58.98  ? 28  ARG A CZ  1 
ATOM   239   N NH1 . ARG A 1 28  ? -23.732 -51.150 -43.604 1.00 52.44  ? 28  ARG A NH1 1 
ATOM   240   N NH2 . ARG A 1 28  ? -24.801 -50.958 -45.629 1.00 58.71  ? 28  ARG A NH2 1 
ATOM   241   N N   . LYS A 1 29  ? -17.112 -49.708 -42.716 1.00 42.91  ? 29  LYS A N   1 
ATOM   242   C CA  . LYS A 1 29  ? -15.719 -49.352 -42.556 1.00 44.36  ? 29  LYS A CA  1 
ATOM   243   C C   . LYS A 1 29  ? -15.373 -48.091 -43.329 1.00 45.99  ? 29  LYS A C   1 
ATOM   244   O O   . LYS A 1 29  ? -15.761 -47.991 -44.478 1.00 40.64  ? 29  LYS A O   1 
ATOM   245   C CB  . LYS A 1 29  ? -14.865 -50.495 -43.084 1.00 45.40  ? 29  LYS A CB  1 
ATOM   246   C CG  . LYS A 1 29  ? -13.428 -50.127 -43.339 1.00 48.98  ? 29  LYS A CG  1 
ATOM   247   C CD  . LYS A 1 29  ? -12.609 -51.325 -43.624 1.00 46.79  ? 29  LYS A CD  1 
ATOM   248   C CE  . LYS A 1 29  ? -11.208 -50.942 -44.014 1.00 45.92  ? 29  LYS A CE  1 
ATOM   249   N NZ  . LYS A 1 29  ? -10.372 -52.152 -44.080 1.00 46.72  ? 29  LYS A NZ  1 
ATOM   250   N N   . THR A 1 30  ? -14.590 -47.182 -42.710 1.00 43.99  ? 30  THR A N   1 
ATOM   251   C CA  . THR A 1 30  ? -14.115 -45.969 -43.364 1.00 40.62  ? 30  THR A CA  1 
ATOM   252   C C   . THR A 1 30  ? -12.636 -46.050 -43.725 1.00 36.44  ? 30  THR A C   1 
ATOM   253   O O   . THR A 1 30  ? -12.194 -45.352 -44.621 1.00 39.51  ? 30  THR A O   1 
ATOM   254   C CB  . THR A 1 30  ? -14.307 -44.720 -42.478 1.00 43.37  ? 30  THR A CB  1 
ATOM   255   O OG1 . THR A 1 30  ? -13.605 -44.922 -41.246 1.00 39.60  ? 30  THR A OG1 1 
ATOM   256   C CG2 . THR A 1 30  ? -15.756 -44.451 -42.160 1.00 43.27  ? 30  THR A CG2 1 
ATOM   257   N N   . MET A 1 31  ? -11.836 -46.830 -42.995 1.00 36.11  ? 31  MET A N   1 
ATOM   258   C CA  . MET A 1 31  ? -10.409 -46.903 -43.264 1.00 32.29  ? 31  MET A CA  1 
ATOM   259   C C   . MET A 1 31  ? -9.805  -47.916 -42.293 1.00 32.63  ? 31  MET A C   1 
ATOM   260   O O   . MET A 1 31  ? -10.507 -48.455 -41.435 1.00 36.66  ? 31  MET A O   1 
ATOM   261   C CB  . MET A 1 31  ? -9.716  -45.546 -43.065 1.00 40.93  ? 31  MET A CB  1 
ATOM   262   C CG  . MET A 1 31  ? -10.005 -44.918 -41.675 1.00 45.45  ? 31  MET A CG  1 
ATOM   263   S SD  . MET A 1 31  ? -9.327  -43.231 -41.417 1.00 41.83  ? 31  MET A SD  1 
ATOM   264   C CE  . MET A 1 31  ? -7.575  -43.458 -41.678 1.00 33.24  ? 31  MET A CE  1 
ATOM   265   N N   . ASP A 1 32  ? -8.508  -48.190 -42.465 1.00 36.61  ? 32  ASP A N   1 
ATOM   266   C CA  . ASP A 1 32  ? -7.747  -49.015 -41.549 1.00 38.04  ? 32  ASP A CA  1 
ATOM   267   C C   . ASP A 1 32  ? -7.135  -48.146 -40.447 1.00 43.00  ? 32  ASP A C   1 
ATOM   268   O O   . ASP A 1 32  ? -6.569  -47.081 -40.724 1.00 40.20  ? 32  ASP A O   1 
ATOM   269   C CB  . ASP A 1 32  ? -6.594  -49.716 -42.269 1.00 37.56  ? 32  ASP A CB  1 
ATOM   270   C CG  . ASP A 1 32  ? -7.017  -50.851 -43.210 1.00 43.24  ? 32  ASP A CG  1 
ATOM   271   O OD1 . ASP A 1 32  ? -8.172  -51.322 -43.113 1.00 41.66  ? 32  ASP A OD1 1 
ATOM   272   O OD2 . ASP A 1 32  ? -6.179  -51.279 -44.002 1.00 47.27  ? 32  ASP A OD2 1 
ATOM   273   N N   . CYS A 1 33  ? -7.229  -48.646 -39.209 1.00 37.64  ? 33  CYS A N   1 
ATOM   274   C CA  . CYS A 1 33  ? -6.493  -48.093 -38.096 1.00 38.61  ? 33  CYS A CA  1 
ATOM   275   C C   . CYS A 1 33  ? -5.149  -48.818 -37.995 1.00 39.27  ? 33  CYS A C   1 
ATOM   276   O O   . CYS A 1 33  ? -5.094  -50.037 -38.063 1.00 43.08  ? 33  CYS A O   1 
ATOM   277   C CB  . CYS A 1 33  ? -7.354  -48.250 -36.850 1.00 45.34  ? 33  CYS A CB  1 
ATOM   278   S SG  . CYS A 1 33  ? -6.615  -47.502 -35.379 1.00 41.54  ? 33  CYS A SG  1 
ATOM   279   N N   . THR A 1 34  ? -4.058  -48.066 -37.883 1.00 39.80  ? 34  THR A N   1 
ATOM   280   C CA  . THR A 1 34  ? -2.709  -48.615 -37.898 1.00 38.08  ? 34  THR A CA  1 
ATOM   281   C C   . THR A 1 34  ? -1.965  -48.269 -36.604 1.00 40.68  ? 34  THR A C   1 
ATOM   282   O O   . THR A 1 34  ? -2.413  -47.409 -35.837 1.00 39.97  ? 34  THR A O   1 
ATOM   283   C CB  . THR A 1 34  ? -1.953  -48.112 -39.136 1.00 44.43  ? 34  THR A CB  1 
ATOM   284   O OG1 . THR A 1 34  ? -1.601  -46.737 -38.963 1.00 36.57  ? 34  THR A OG1 1 
ATOM   285   C CG2 . THR A 1 34  ? -2.745  -48.283 -40.423 1.00 42.03  ? 34  THR A CG2 1 
ATOM   286   N N   . ILE A 1 35  ? -0.846  -48.975 -36.369 1.00 36.32  ? 35  ILE A N   1 
ATOM   287   C CA  . ILE A 1 35  ? 0.098   -48.694 -35.295 1.00 35.41  ? 35  ILE A CA  1 
ATOM   288   C C   . ILE A 1 35  ? 0.585   -47.251 -35.379 1.00 42.16  ? 35  ILE A C   1 
ATOM   289   O O   . ILE A 1 35  ? 0.743   -46.560 -34.355 1.00 37.12  ? 35  ILE A O   1 
ATOM   290   C CB  . ILE A 1 35  ? 1.257   -49.707 -35.335 1.00 35.26  ? 35  ILE A CB  1 
ATOM   291   C CG1 . ILE A 1 35  ? 0.733   -51.104 -35.000 1.00 37.17  ? 35  ILE A CG1 1 
ATOM   292   C CG2 . ILE A 1 35  ? 2.416   -49.282 -34.438 1.00 35.98  ? 35  ILE A CG2 1 
ATOM   293   C CD1 . ILE A 1 35  ? 1.785   -52.141 -34.762 1.00 44.15  ? 35  ILE A CD1 1 
ATOM   294   N N   . GLY A 1 36  ? 0.833   -46.818 -36.618 1.00 35.62  ? 36  GLY A N   1 
ATOM   295   C CA  . GLY A 1 36  ? 1.302   -45.473 -36.898 1.00 35.91  ? 36  GLY A CA  1 
ATOM   296   C C   . GLY A 1 36  ? 0.319   -44.423 -36.374 1.00 38.76  ? 36  GLY A C   1 
ATOM   297   O O   . GLY A 1 36  ? 0.799   -43.412 -35.875 1.00 36.32  ? 36  GLY A O   1 
ATOM   298   N N   . HIS A 1 37  ? -1.008  -44.692 -36.459 1.00 32.12  ? 37  HIS A N   1 
ATOM   299   C CA  . HIS A 1 37  ? -2.037  -43.802 -35.923 1.00 35.54  ? 37  HIS A CA  1 
ATOM   300   C C   . HIS A 1 37  ? -1.858  -43.598 -34.415 1.00 39.19  ? 37  HIS A C   1 
ATOM   301   O O   . HIS A 1 37  ? -1.975  -42.485 -33.909 1.00 38.96  ? 37  HIS A O   1 
ATOM   302   C CB  . HIS A 1 37  ? -3.463  -44.291 -36.200 1.00 36.22  ? 37  HIS A CB  1 
ATOM   303   C CG  . HIS A 1 37  ? -3.909  -44.066 -37.611 1.00 38.48  ? 37  HIS A CG  1 
ATOM   304   N ND1 . HIS A 1 37  ? -4.454  -45.067 -38.388 1.00 39.16  ? 37  HIS A ND1 1 
ATOM   305   C CD2 . HIS A 1 37  ? -3.840  -42.974 -38.399 1.00 40.98  ? 37  HIS A CD2 1 
ATOM   306   C CE1 . HIS A 1 37  ? -4.691  -44.581 -39.615 1.00 44.90  ? 37  HIS A CE1 1 
ATOM   307   N NE2 . HIS A 1 37  ? -4.341  -43.300 -39.642 1.00 41.45  ? 37  HIS A NE2 1 
ATOM   308   N N   . ALA A 1 38  ? -1.616  -44.688 -33.699 1.00 37.43  ? 38  ALA A N   1 
ATOM   309   C CA  . ALA A 1 38  ? -1.525  -44.646 -32.248 1.00 38.10  ? 38  ALA A CA  1 
ATOM   310   C C   . ALA A 1 38  ? -0.279  -43.879 -31.794 1.00 37.01  ? 38  ALA A C   1 
ATOM   311   O O   . ALA A 1 38  ? -0.343  -43.119 -30.845 1.00 42.99  ? 38  ALA A O   1 
ATOM   312   C CB  . ALA A 1 38  ? -1.560  -46.054 -31.691 1.00 35.51  ? 38  ALA A CB  1 
ATOM   313   N N   . TYR A 1 39  ? 0.858   -44.061 -32.466 1.00 36.14  ? 39  TYR A N   1 
ATOM   314   C CA  . TYR A 1 39  ? 2.056   -43.301 -32.151 1.00 38.97  ? 39  TYR A CA  1 
ATOM   315   C C   . TYR A 1 39  ? 2.178   -41.989 -32.936 1.00 39.88  ? 39  TYR A C   1 
ATOM   316   O O   . TYR A 1 39  ? 3.178   -41.291 -32.798 1.00 39.79  ? 39  TYR A O   1 
ATOM   317   C CB  . TYR A 1 39  ? 3.304   -44.108 -32.502 1.00 42.96  ? 39  TYR A CB  1 
ATOM   318   C CG  . TYR A 1 39  ? 3.565   -45.267 -31.588 1.00 39.96  ? 39  TYR A CG  1 
ATOM   319   C CD1 . TYR A 1 39  ? 2.938   -46.487 -31.785 1.00 41.26  ? 39  TYR A CD1 1 
ATOM   320   C CD2 . TYR A 1 39  ? 4.388   -45.118 -30.482 1.00 40.85  ? 39  TYR A CD2 1 
ATOM   321   C CE1 . TYR A 1 39  ? 3.187   -47.560 -30.942 1.00 43.97  ? 39  TYR A CE1 1 
ATOM   322   C CE2 . TYR A 1 39  ? 4.613   -46.165 -29.609 1.00 38.85  ? 39  TYR A CE2 1 
ATOM   323   C CZ  . TYR A 1 39  ? 4.033   -47.401 -29.864 1.00 43.47  ? 39  TYR A CZ  1 
ATOM   324   O OH  . TYR A 1 39  ? 4.248   -48.431 -29.009 1.00 44.41  ? 39  TYR A OH  1 
ATOM   325   N N   . GLY A 1 40  ? 1.227   -41.683 -33.824 1.00 32.05  ? 40  GLY A N   1 
ATOM   326   C CA  . GLY A 1 40  ? 1.404   -40.559 -34.713 1.00 36.49  ? 40  GLY A CA  1 
ATOM   327   C C   . GLY A 1 40  ? 0.328   -39.523 -34.455 1.00 34.61  ? 40  GLY A C   1 
ATOM   328   O O   . GLY A 1 40  ? 0.029   -38.745 -35.323 1.00 39.21  ? 40  GLY A O   1 
ATOM   329   N N   . GLY A 1 41  ? -0.294  -39.579 -33.280 1.00 34.53  ? 41  GLY A N   1 
ATOM   330   C CA  . GLY A 1 41  ? -1.301  -38.612 -32.906 1.00 36.07  ? 41  GLY A CA  1 
ATOM   331   C C   . GLY A 1 41  ? -2.565  -38.681 -33.750 1.00 40.29  ? 41  GLY A C   1 
ATOM   332   O O   . GLY A 1 41  ? -3.206  -37.650 -33.966 1.00 34.40  ? 41  GLY A O   1 
ATOM   333   N N   . MET A 1 42  ? -2.923  -39.900 -34.198 1.00 36.74  ? 42  MET A N   1 
ATOM   334   C CA  . MET A 1 42  ? -4.180  -40.165 -34.878 1.00 34.02  ? 42  MET A CA  1 
ATOM   335   C C   . MET A 1 42  ? -4.315  -39.416 -36.192 1.00 32.22  ? 42  MET A C   1 
ATOM   336   O O   . MET A 1 42  ? -5.437  -39.284 -36.683 1.00 41.07  ? 42  MET A O   1 
ATOM   337   C CB  . MET A 1 42  ? -5.397  -39.745 -34.043 1.00 36.16  ? 42  MET A CB  1 
ATOM   338   C CG  . MET A 1 42  ? -5.519  -40.409 -32.690 1.00 42.38  ? 42  MET A CG  1 
ATOM   339   S SD  . MET A 1 42  ? -7.148  -40.020 -31.933 1.00 44.02  ? 42  MET A SD  1 
ATOM   340   C CE  . MET A 1 42  ? -6.833  -40.448 -30.220 1.00 50.27  ? 42  MET A CE  1 
ATOM   341   N N   . ARG A 1 43  ? -3.221  -38.955 -36.776 1.00 31.21  ? 43  ARG A N   1 
ATOM   342   C CA  . ARG A 1 43  ? -3.263  -38.194 -38.017 1.00 39.22  ? 43  ARG A CA  1 
ATOM   343   C C   . ARG A 1 43  ? -4.035  -38.952 -39.086 1.00 39.87  ? 43  ARG A C   1 
ATOM   344   O O   . ARG A 1 43  ? -3.685  -40.081 -39.386 1.00 38.70  ? 43  ARG A O   1 
ATOM   345   C CB  . ARG A 1 43  ? -1.857  -37.916 -38.557 1.00 45.69  ? 43  ARG A CB  1 
ATOM   346   C CG  . ARG A 1 43  ? -1.771  -36.679 -39.442 1.00 58.93  ? 43  ARG A CG  1 
ATOM   347   C CD  . ARG A 1 43  ? -2.079  -35.400 -38.661 1.00 72.35  ? 43  ARG A CD  1 
ATOM   348   N NE  . ARG A 1 43  ? -1.760  -35.557 -37.237 1.00 80.77  ? 43  ARG A NE  1 
ATOM   349   C CZ  . ARG A 1 43  ? -0.713  -35.019 -36.615 1.00 72.96  ? 43  ARG A CZ  1 
ATOM   350   N NH1 . ARG A 1 43  ? -0.188  -33.902 -37.083 1.00 69.55  ? 43  ARG A NH1 1 
ATOM   351   N NH2 . ARG A 1 43  ? -0.234  -35.579 -35.508 1.00 52.52  ? 43  ARG A NH2 1 
ATOM   352   N N   . GLY A 1 44  ? -5.111  -38.334 -39.596 1.00 40.56  ? 44  GLY A N   1 
ATOM   353   C CA  . GLY A 1 44  ? -5.896  -38.874 -40.701 1.00 44.52  ? 44  GLY A CA  1 
ATOM   354   C C   . GLY A 1 44  ? -6.998  -39.817 -40.238 1.00 42.67  ? 44  GLY A C   1 
ATOM   355   O O   . GLY A 1 44  ? -7.872  -40.201 -41.010 1.00 36.88  ? 44  GLY A O   1 
ATOM   356   N N   . LEU A 1 45  ? -6.970  -40.190 -38.956 1.00 38.26  ? 45  LEU A N   1 
ATOM   357   C CA  . LEU A 1 45  ? -7.916  -41.175 -38.484 1.00 36.37  ? 45  LEU A CA  1 
ATOM   358   C C   . LEU A 1 45  ? -9.287  -40.523 -38.313 1.00 41.03  ? 45  LEU A C   1 
ATOM   359   O O   . LEU A 1 45  ? -9.405  -39.500 -37.631 1.00 42.78  ? 45  LEU A O   1 
ATOM   360   C CB  . LEU A 1 45  ? -7.367  -41.754 -37.185 1.00 36.55  ? 45  LEU A CB  1 
ATOM   361   C CG  . LEU A 1 45  ? -8.020  -43.046 -36.718 1.00 42.46  ? 45  LEU A CG  1 
ATOM   362   C CD1 . LEU A 1 45  ? -7.674  -44.212 -37.659 1.00 40.89  ? 45  LEU A CD1 1 
ATOM   363   C CD2 . LEU A 1 45  ? -7.579  -43.336 -35.292 1.00 45.52  ? 45  LEU A CD2 1 
ATOM   364   N N   . LYS A 1 46  ? -10.310 -41.102 -38.971 1.00 42.39  ? 46  LYS A N   1 
ATOM   365   C CA  . LYS A 1 46  ? -11.681 -40.579 -38.980 1.00 38.92  ? 46  LYS A CA  1 
ATOM   366   C C   . LYS A 1 46  ? -12.438 -40.993 -37.712 1.00 37.88  ? 46  LYS A C   1 
ATOM   367   O O   . LYS A 1 46  ? -13.290 -41.883 -37.727 1.00 39.94  ? 46  LYS A O   1 
ATOM   368   C CB  . LYS A 1 46  ? -12.396 -41.042 -40.258 1.00 38.95  ? 46  LYS A CB  1 
ATOM   369   C CG  . LYS A 1 46  ? -11.866 -40.445 -41.560 1.00 40.38  ? 46  LYS A CG  1 
ATOM   370   C CD  . LYS A 1 46  ? -12.583 -40.996 -42.778 1.00 44.53  ? 46  LYS A CD  1 
ATOM   371   C CE  . LYS A 1 46  ? -12.285 -40.241 -44.052 1.00 47.65  ? 46  LYS A CE  1 
ATOM   372   N NZ  . LYS A 1 46  ? -10.873 -40.408 -44.451 1.00 52.28  ? 46  LYS A NZ  1 
ATOM   373   N N   . ALA A 1 47  ? -12.158 -40.296 -36.596 1.00 38.32  ? 47  ALA A N   1 
ATOM   374   C CA  . ALA A 1 47  ? -12.458 -40.788 -35.260 1.00 34.40  ? 47  ALA A CA  1 
ATOM   375   C C   . ALA A 1 47  ? -13.545 -39.973 -34.555 1.00 39.29  ? 47  ALA A C   1 
ATOM   376   O O   . ALA A 1 47  ? -14.002 -40.379 -33.476 1.00 39.21  ? 47  ALA A O   1 
ATOM   377   C CB  . ALA A 1 47  ? -11.186 -40.810 -34.434 1.00 38.74  ? 47  ALA A CB  1 
ATOM   378   N N   . LEU A 1 48  ? -13.983 -38.875 -35.188 1.00 33.98  ? 48  LEU A N   1 
ATOM   379   C CA  . LEU A 1 48  ? -14.808 -37.851 -34.557 1.00 39.31  ? 48  LEU A CA  1 
ATOM   380   C C   . LEU A 1 48  ? -15.840 -37.393 -35.566 1.00 35.79  ? 48  LEU A C   1 
ATOM   381   O O   . LEU A 1 48  ? -15.529 -37.417 -36.753 1.00 35.55  ? 48  LEU A O   1 
ATOM   382   C CB  . LEU A 1 48  ? -13.959 -36.610 -34.224 1.00 40.44  ? 48  LEU A CB  1 
ATOM   383   C CG  . LEU A 1 48  ? -12.985 -36.733 -33.065 1.00 47.08  ? 48  LEU A CG  1 
ATOM   384   C CD1 . LEU A 1 48  ? -12.459 -35.367 -32.685 1.00 47.82  ? 48  LEU A CD1 1 
ATOM   385   C CD2 . LEU A 1 48  ? -13.661 -37.374 -31.874 1.00 50.40  ? 48  LEU A CD2 1 
ATOM   386   N N   . VAL A 1 49  ? -16.951 -36.844 -35.050 1.00 34.04  ? 49  VAL A N   1 
ATOM   387   C CA  . VAL A 1 49  ? -18.012 -36.207 -35.817 1.00 37.82  ? 49  VAL A CA  1 
ATOM   388   C C   . VAL A 1 49  ? -17.970 -34.699 -35.567 1.00 42.69  ? 49  VAL A C   1 
ATOM   389   O O   . VAL A 1 49  ? -17.895 -34.276 -34.412 1.00 36.99  ? 49  VAL A O   1 
ATOM   390   C CB  . VAL A 1 49  ? -19.400 -36.743 -35.406 1.00 37.29  ? 49  VAL A CB  1 
ATOM   391   C CG1 . VAL A 1 49  ? -20.529 -35.981 -36.086 1.00 41.05  ? 49  VAL A CG1 1 
ATOM   392   C CG2 . VAL A 1 49  ? -19.538 -38.227 -35.684 1.00 45.23  ? 49  VAL A CG2 1 
ATOM   393   N N   . CYS A 1 50  ? -18.124 -33.908 -36.642 1.00 39.95  ? 50  CYS A N   1 
ATOM   394   C CA  . CYS A 1 50  ? -18.311 -32.464 -36.539 1.00 39.75  ? 50  CYS A CA  1 
ATOM   395   C C   . CYS A 1 50  ? -19.172 -31.985 -37.707 1.00 35.52  ? 50  CYS A C   1 
ATOM   396   O O   . CYS A 1 50  ? -18.760 -32.132 -38.845 1.00 37.74  ? 50  CYS A O   1 
ATOM   397   C CB  . CYS A 1 50  ? -16.977 -31.720 -36.549 1.00 43.20  ? 50  CYS A CB  1 
ATOM   398   S SG  . CYS A 1 50  ? -17.128 -29.905 -36.514 1.00 40.33  ? 50  CYS A SG  1 
ATOM   399   N N   . ASP A 1 51  ? -20.352 -31.411 -37.415 1.00 36.09  ? 51  ASP A N   1 
ATOM   400   C CA  . ASP A 1 51  ? -21.245 -30.935 -38.456 1.00 35.44  ? 51  ASP A CA  1 
ATOM   401   C C   . ASP A 1 51  ? -21.151 -29.429 -38.662 1.00 40.14  ? 51  ASP A C   1 
ATOM   402   O O   . ASP A 1 51  ? -21.661 -28.941 -39.663 1.00 40.65  ? 51  ASP A O   1 
ATOM   403   C CB  . ASP A 1 51  ? -22.673 -31.398 -38.196 1.00 39.05  ? 51  ASP A CB  1 
ATOM   404   C CG  . ASP A 1 51  ? -22.825 -32.888 -38.470 1.00 36.81  ? 51  ASP A CG  1 
ATOM   405   O OD1 . ASP A 1 51  ? -22.200 -33.346 -39.429 1.00 38.46  ? 51  ASP A OD1 1 
ATOM   406   O OD2 . ASP A 1 51  ? -23.500 -33.563 -37.676 1.00 39.19  ? 51  ASP A OD2 1 
ATOM   407   N N   . THR A 1 52  ? -20.423 -28.707 -37.798 1.00 34.66  ? 52  THR A N   1 
ATOM   408   C CA  . THR A 1 52  ? -20.364 -27.263 -37.914 1.00 33.70  ? 52  THR A CA  1 
ATOM   409   C C   . THR A 1 52  ? -19.496 -26.844 -39.095 1.00 33.58  ? 52  THR A C   1 
ATOM   410   O O   . THR A 1 52  ? -19.775 -25.884 -39.805 1.00 37.63  ? 52  THR A O   1 
ATOM   411   C CB  . THR A 1 52  ? -19.888 -26.653 -36.596 1.00 32.06  ? 52  THR A CB  1 
ATOM   412   O OG1 . THR A 1 52  ? -18.647 -27.257 -36.241 1.00 31.89  ? 52  THR A OG1 1 
ATOM   413   C CG2 . THR A 1 52  ? -20.868 -26.883 -35.474 1.00 34.13  ? 52  THR A CG2 1 
ATOM   414   N N   . SER A 1 53  ? -18.387 -27.522 -39.295 1.00 34.52  ? 53  SER A N   1 
ATOM   415   C CA  . SER A 1 53  ? -17.480 -27.114 -40.345 1.00 33.07  ? 53  SER A CA  1 
ATOM   416   C C   . SER A 1 53  ? -16.740 -28.342 -40.839 1.00 34.03  ? 53  SER A C   1 
ATOM   417   O O   . SER A 1 53  ? -16.743 -29.361 -40.142 1.00 35.05  ? 53  SER A O   1 
ATOM   418   C CB  . SER A 1 53  ? -16.499 -26.065 -39.841 1.00 33.31  ? 53  SER A CB  1 
ATOM   419   O OG  . SER A 1 53  ? -15.717 -26.612 -38.794 1.00 37.60  ? 53  SER A OG  1 
ATOM   420   N N   . GLU A 1 54  ? -16.098 -28.180 -42.004 1.00 32.79  ? 54  GLU A N   1 
ATOM   421   C CA  . GLU A 1 54  ? -15.383 -29.254 -42.686 1.00 39.35  ? 54  GLU A CA  1 
ATOM   422   C C   . GLU A 1 54  ? -14.237 -28.651 -43.498 1.00 37.82  ? 54  GLU A C   1 
ATOM   423   O O   . GLU A 1 54  ? -14.449 -27.736 -44.283 1.00 41.83  ? 54  GLU A O   1 
ATOM   424   C CB  . GLU A 1 54  ? -16.344 -30.020 -43.600 1.00 41.56  ? 54  GLU A CB  1 
ATOM   425   C CG  . GLU A 1 54  ? -15.732 -31.221 -44.290 1.00 47.70  ? 54  GLU A CG  1 
ATOM   426   C CD  . GLU A 1 54  ? -16.668 -32.002 -45.216 1.00 57.72  ? 54  GLU A CD  1 
ATOM   427   O OE1 . GLU A 1 54  ? -16.281 -33.122 -45.626 1.00 55.60  ? 54  GLU A OE1 1 
ATOM   428   O OE2 . GLU A 1 54  ? -17.765 -31.480 -45.555 1.00 56.74  ? 54  GLU A OE2 1 
ATOM   429   N N   . VAL A 1 55  ? -13.030 -29.184 -43.303 1.00 46.26  ? 55  VAL A N   1 
ATOM   430   C CA  . VAL A 1 55  ? -11.825 -28.706 -43.972 1.00 50.97  ? 55  VAL A CA  1 
ATOM   431   C C   . VAL A 1 55  ? -11.525 -29.626 -45.156 1.00 60.15  ? 55  VAL A C   1 
ATOM   432   O O   . VAL A 1 55  ? -11.129 -30.777 -44.955 1.00 67.62  ? 55  VAL A O   1 
ATOM   433   C CB  . VAL A 1 55  ? -10.602 -28.651 -43.030 1.00 54.29  ? 55  VAL A CB  1 
ATOM   434   C CG1 . VAL A 1 55  ? -9.370  -28.145 -43.772 1.00 62.34  ? 55  VAL A CG1 1 
ATOM   435   C CG2 . VAL A 1 55  ? -10.840 -27.811 -41.779 1.00 60.34  ? 55  VAL A CG2 1 
ATOM   436   N N   . PHE A 1 56  ? -11.723 -29.092 -46.371 1.00 53.71  ? 56  PHE A N   1 
ATOM   437   C CA  . PHE A 1 56  ? -11.357 -29.729 -47.626 1.00 59.38  ? 56  PHE A CA  1 
ATOM   438   C C   . PHE A 1 56  ? -9.886  -29.435 -47.931 1.00 73.24  ? 56  PHE A C   1 
ATOM   439   O O   . PHE A 1 56  ? -9.567  -28.292 -48.245 1.00 64.31  ? 56  PHE A O   1 
ATOM   440   C CB  . PHE A 1 56  ? -12.227 -29.200 -48.773 1.00 51.29  ? 56  PHE A CB  1 
ATOM   441   C CG  . PHE A 1 56  ? -13.694 -29.505 -48.612 1.00 57.01  ? 56  PHE A CG  1 
ATOM   442   C CD1 . PHE A 1 56  ? -14.508 -28.711 -47.813 1.00 51.15  ? 56  PHE A CD1 1 
ATOM   443   C CD2 . PHE A 1 56  ? -14.245 -30.648 -49.181 1.00 56.18  ? 56  PHE A CD2 1 
ATOM   444   C CE1 . PHE A 1 56  ? -15.846 -29.025 -47.634 1.00 49.10  ? 56  PHE A CE1 1 
ATOM   445   C CE2 . PHE A 1 56  ? -15.582 -30.961 -48.991 1.00 47.72  ? 56  PHE A CE2 1 
ATOM   446   C CZ  . PHE A 1 56  ? -16.380 -30.144 -48.229 1.00 45.89  ? 56  PHE A CZ  1 
ATOM   447   N N   . PRO A 1 57  ? -8.960  -30.429 -47.850 1.00 74.86  ? 57  PRO A N   1 
ATOM   448   C CA  . PRO A 1 57  ? -7.531  -30.205 -48.106 1.00 77.76  ? 57  PRO A CA  1 
ATOM   449   C C   . PRO A 1 57  ? -7.180  -29.386 -49.347 1.00 66.55  ? 57  PRO A C   1 
ATOM   450   O O   . PRO A 1 57  ? -6.132  -28.729 -49.370 1.00 55.23  ? 57  PRO A O   1 
ATOM   451   C CB  . PRO A 1 57  ? -6.961  -31.625 -48.287 1.00 83.07  ? 57  PRO A CB  1 
ATOM   452   C CG  . PRO A 1 57  ? -7.870  -32.501 -47.445 1.00 86.08  ? 57  PRO A CG  1 
ATOM   453   C CD  . PRO A 1 57  ? -9.232  -31.826 -47.469 1.00 80.19  ? 57  PRO A CD  1 
ATOM   454   N N   . ASP A 1 58  ? -8.080  -29.406 -50.341 1.00 63.56  ? 58  ASP A N   1 
ATOM   455   C CA  . ASP A 1 58  ? -7.873  -28.723 -51.611 1.00 74.67  ? 58  ASP A CA  1 
ATOM   456   C C   . ASP A 1 58  ? -8.801  -27.517 -51.791 1.00 70.56  ? 58  ASP A C   1 
ATOM   457   O O   . ASP A 1 58  ? -8.874  -26.980 -52.889 1.00 67.36  ? 58  ASP A O   1 
ATOM   458   C CB  . ASP A 1 58  ? -8.070  -29.710 -52.772 1.00 87.88  ? 58  ASP A CB  1 
ATOM   459   C CG  . ASP A 1 58  ? -7.086  -30.877 -52.812 1.00 92.93  ? 58  ASP A CG  1 
ATOM   460   O OD1 . ASP A 1 58  ? -6.014  -30.791 -52.169 1.00 99.32  ? 58  ASP A OD1 1 
ATOM   461   O OD2 . ASP A 1 58  ? -7.399  -31.878 -53.481 1.00 92.90  ? 58  ASP A OD2 1 
ATOM   462   N N   . GLU A 1 59  ? -9.518  -27.074 -50.744 1.00 71.21  ? 59  GLU A N   1 
ATOM   463   C CA  . GLU A 1 59  ? -10.325 -25.856 -50.843 1.00 68.92  ? 59  GLU A CA  1 
ATOM   464   C C   . GLU A 1 59  ? -10.368 -25.047 -49.537 1.00 60.57  ? 59  GLU A C   1 
ATOM   465   O O   . GLU A 1 59  ? -10.826 -23.903 -49.531 1.00 51.30  ? 59  GLU A O   1 
ATOM   466   C CB  . GLU A 1 59  ? -11.786 -26.163 -51.182 1.00 78.71  ? 59  GLU A CB  1 
ATOM   467   C CG  . GLU A 1 59  ? -12.017 -26.999 -52.428 1.00 78.66  ? 59  GLU A CG  1 
ATOM   468   C CD  . GLU A 1 59  ? -13.495 -27.316 -52.599 1.00 78.95  ? 59  GLU A CD  1 
ATOM   469   O OE1 . GLU A 1 59  ? -14.292 -26.361 -52.697 1.00 72.04  ? 59  GLU A OE1 1 
ATOM   470   O OE2 . GLU A 1 59  ? -13.855 -28.510 -52.588 1.00 77.74  ? 59  GLU A OE2 1 
ATOM   471   N N   . GLY A 1 60  ? -9.946  -25.641 -48.417 1.00 58.36  ? 60  GLY A N   1 
ATOM   472   C CA  . GLY A 1 60  ? -10.002 -24.967 -47.128 1.00 55.69  ? 60  GLY A CA  1 
ATOM   473   C C   . GLY A 1 60  ? -11.345 -25.166 -46.433 1.00 50.98  ? 60  GLY A C   1 
ATOM   474   O O   . GLY A 1 60  ? -12.134 -26.032 -46.817 1.00 47.71  ? 60  GLY A O   1 
ATOM   475   N N   . VAL A 1 61  ? -11.578 -24.364 -45.385 1.00 43.70  ? 61  VAL A N   1 
ATOM   476   C CA  . VAL A 1 61  ? -12.690 -24.623 -44.498 1.00 34.28  ? 61  VAL A CA  1 
ATOM   477   C C   . VAL A 1 61  ? -13.967 -24.117 -45.158 1.00 32.16  ? 61  VAL A C   1 
ATOM   478   O O   . VAL A 1 61  ? -13.958 -23.067 -45.789 1.00 36.46  ? 61  VAL A O   1 
ATOM   479   C CB  . VAL A 1 61  ? -12.473 -24.007 -43.104 1.00 36.24  ? 61  VAL A CB  1 
ATOM   480   C CG1 . VAL A 1 61  ? -12.527 -22.479 -43.130 1.00 37.58  ? 61  VAL A CG1 1 
ATOM   481   C CG2 . VAL A 1 61  ? -13.477 -24.578 -42.104 1.00 36.72  ? 61  VAL A CG2 1 
ATOM   482   N N   . LYS A 1 62  ? -15.050 -24.888 -44.969 1.00 37.08  ? 62  LYS A N   1 
ATOM   483   C CA  . LYS A 1 62  ? -16.408 -24.448 -45.237 1.00 36.44  ? 62  LYS A CA  1 
ATOM   484   C C   . LYS A 1 62  ? -17.226 -24.561 -43.964 1.00 35.01  ? 62  LYS A C   1 
ATOM   485   O O   . LYS A 1 62  ? -17.112 -25.538 -43.223 1.00 35.87  ? 62  LYS A O   1 
ATOM   486   C CB  . LYS A 1 62  ? -17.097 -25.324 -46.289 1.00 39.96  ? 62  LYS A CB  1 
ATOM   487   C CG  . LYS A 1 62  ? -16.458 -25.309 -47.669 1.00 45.29  ? 62  LYS A CG  1 
ATOM   488   C CD  . LYS A 1 62  ? -17.309 -26.027 -48.708 1.00 50.40  ? 62  LYS A CD  1 
ATOM   489   C CE  . LYS A 1 62  ? -16.533 -26.376 -49.964 1.00 56.56  ? 62  LYS A CE  1 
ATOM   490   N NZ  . LYS A 1 62  ? -17.452 -26.589 -51.107 1.00 59.67  ? 62  LYS A NZ  1 
ATOM   491   N N   . PHE A 1 63  ? -18.096 -23.575 -43.765 1.00 34.50  ? 63  PHE A N   1 
ATOM   492   C CA  . PHE A 1 63  ? -18.945 -23.540 -42.594 1.00 33.69  ? 63  PHE A CA  1 
ATOM   493   C C   . PHE A 1 63  ? -20.356 -23.930 -43.015 1.00 34.20  ? 63  PHE A C   1 
ATOM   494   O O   . PHE A 1 63  ? -21.006 -23.173 -43.741 1.00 36.90  ? 63  PHE A O   1 
ATOM   495   C CB  . PHE A 1 63  ? -18.949 -22.132 -42.006 1.00 33.58  ? 63  PHE A CB  1 
ATOM   496   C CG  . PHE A 1 63  ? -17.628 -21.545 -41.583 1.00 34.09  ? 63  PHE A CG  1 
ATOM   497   C CD1 . PHE A 1 63  ? -16.754 -22.242 -40.763 1.00 38.36  ? 63  PHE A CD1 1 
ATOM   498   C CD2 . PHE A 1 63  ? -17.321 -20.224 -41.883 1.00 40.43  ? 63  PHE A CD2 1 
ATOM   499   C CE1 . PHE A 1 63  ? -15.557 -21.683 -40.343 1.00 36.74  ? 63  PHE A CE1 1 
ATOM   500   C CE2 . PHE A 1 63  ? -16.125 -19.656 -41.453 1.00 41.22  ? 63  PHE A CE2 1 
ATOM   501   C CZ  . PHE A 1 63  ? -15.248 -20.383 -40.682 1.00 40.47  ? 63  PHE A CZ  1 
ATOM   502   N N   . ARG A 1 64  ? -20.836 -25.080 -42.520 1.00 35.30  ? 64  ARG A N   1 
ATOM   503   C CA  . ARG A 1 64  ? -22.099 -25.661 -42.944 1.00 35.09  ? 64  ARG A CA  1 
ATOM   504   C C   . ARG A 1 64  ? -22.216 -25.613 -44.479 1.00 37.32  ? 64  ARG A C   1 
ATOM   505   O O   . ARG A 1 64  ? -23.231 -25.193 -45.018 1.00 37.74  ? 64  ARG A O   1 
ATOM   506   C CB  . ARG A 1 64  ? -23.213 -24.890 -42.239 1.00 35.81  ? 64  ARG A CB  1 
ATOM   507   C CG  . ARG A 1 64  ? -23.367 -25.208 -40.761 1.00 34.73  ? 64  ARG A CG  1 
ATOM   508   C CD  . ARG A 1 64  ? -23.914 -26.598 -40.541 1.00 32.76  ? 64  ARG A CD  1 
ATOM   509   N NE  . ARG A 1 64  ? -24.398 -26.740 -39.180 1.00 33.92  ? 64  ARG A NE  1 
ATOM   510   C CZ  . ARG A 1 64  ? -25.022 -27.812 -38.719 1.00 35.82  ? 64  ARG A CZ  1 
ATOM   511   N NH1 . ARG A 1 64  ? -25.363 -28.777 -39.543 1.00 36.22  ? 64  ARG A NH1 1 
ATOM   512   N NH2 . ARG A 1 64  ? -25.297 -27.933 -37.436 1.00 38.02  ? 64  ARG A NH2 1 
ATOM   513   N N   . GLY A 1 65  ? -21.147 -25.951 -45.198 1.00 36.66  ? 65  GLY A N   1 
ATOM   514   C CA  . GLY A 1 65  ? -21.220 -26.085 -46.651 1.00 38.58  ? 65  GLY A CA  1 
ATOM   515   C C   . GLY A 1 65  ? -20.949 -24.777 -47.389 1.00 44.49  ? 65  GLY A C   1 
ATOM   516   O O   . GLY A 1 65  ? -20.848 -24.763 -48.611 1.00 42.91  ? 65  GLY A O   1 
ATOM   517   N N   . TYR A 1 66  ? -20.775 -23.677 -46.651 1.00 42.96  ? 66  TYR A N   1 
ATOM   518   C CA  . TYR A 1 66  ? -20.500 -22.400 -47.293 1.00 40.28  ? 66  TYR A CA  1 
ATOM   519   C C   . TYR A 1 66  ? -19.028 -22.048 -47.187 1.00 42.66  ? 66  TYR A C   1 
ATOM   520   O O   . TYR A 1 66  ? -18.385 -22.363 -46.195 1.00 39.32  ? 66  TYR A O   1 
ATOM   521   C CB  . TYR A 1 66  ? -21.340 -21.298 -46.676 1.00 36.23  ? 66  TYR A CB  1 
ATOM   522   C CG  . TYR A 1 66  ? -22.818 -21.502 -46.878 1.00 42.05  ? 66  TYR A CG  1 
ATOM   523   C CD1 . TYR A 1 66  ? -23.460 -21.070 -48.035 1.00 47.35  ? 66  TYR A CD1 1 
ATOM   524   C CD2 . TYR A 1 66  ? -23.577 -22.178 -45.937 1.00 44.18  ? 66  TYR A CD2 1 
ATOM   525   C CE1 . TYR A 1 66  ? -24.828 -21.258 -48.221 1.00 44.87  ? 66  TYR A CE1 1 
ATOM   526   C CE2 . TYR A 1 66  ? -24.941 -22.371 -46.103 1.00 48.47  ? 66  TYR A CE2 1 
ATOM   527   C CZ  . TYR A 1 66  ? -25.568 -21.914 -47.253 1.00 48.65  ? 66  TYR A CZ  1 
ATOM   528   O OH  . TYR A 1 66  ? -26.910 -22.164 -47.411 1.00 43.23  ? 66  TYR A OH  1 
ATOM   529   N N   . THR A 1 67  ? -18.510 -21.407 -48.239 1.00 39.67  ? 67  THR A N   1 
ATOM   530   C CA  . THR A 1 67  ? -17.139 -20.959 -48.271 1.00 40.14  ? 67  THR A CA  1 
ATOM   531   C C   . THR A 1 67  ? -17.027 -19.583 -47.607 1.00 38.26  ? 67  THR A C   1 
ATOM   532   O O   . THR A 1 67  ? -17.996 -18.832 -47.429 1.00 36.02  ? 67  THR A O   1 
ATOM   533   C CB  . THR A 1 67  ? -16.603 -20.917 -49.705 1.00 40.99  ? 67  THR A CB  1 
ATOM   534   O OG1 . THR A 1 67  ? -17.379 -19.897 -50.333 1.00 37.57  ? 67  THR A OG1 1 
ATOM   535   C CG2 . THR A 1 67  ? -16.718 -22.237 -50.432 1.00 43.50  ? 67  THR A CG2 1 
ATOM   536   N N   . ILE A 1 68  ? -15.794 -19.234 -47.271 1.00 38.49  ? 68  ILE A N   1 
ATOM   537   C CA  . ILE A 1 68  ? -15.576 -17.941 -46.659 1.00 40.47  ? 68  ILE A CA  1 
ATOM   538   C C   . ILE A 1 68  ? -15.924 -16.853 -47.673 1.00 45.08  ? 68  ILE A C   1 
ATOM   539   O O   . ILE A 1 68  ? -16.705 -15.943 -47.351 1.00 43.49  ? 68  ILE A O   1 
ATOM   540   C CB  . ILE A 1 68  ? -14.159 -17.904 -46.066 1.00 43.10  ? 68  ILE A CB  1 
ATOM   541   C CG1 . ILE A 1 68  ? -14.194 -18.663 -44.726 1.00 42.43  ? 68  ILE A CG1 1 
ATOM   542   C CG2 . ILE A 1 68  ? -13.636 -16.476 -45.925 1.00 44.74  ? 68  ILE A CG2 1 
ATOM   543   C CD1 . ILE A 1 68  ? -12.867 -18.814 -44.069 1.00 44.86  ? 68  ILE A CD1 1 
ATOM   544   N N   . PRO A 1 69  ? -15.421 -16.909 -48.936 1.00 40.26  ? 69  PRO A N   1 
ATOM   545   C CA  . PRO A 1 69  ? -15.868 -15.941 -49.944 1.00 40.73  ? 69  PRO A CA  1 
ATOM   546   C C   . PRO A 1 69  ? -17.395 -15.842 -50.075 1.00 42.23  ? 69  PRO A C   1 
ATOM   547   O O   . PRO A 1 69  ? -17.935 -14.742 -50.149 1.00 46.46  ? 69  PRO A O   1 
ATOM   548   C CB  . PRO A 1 69  ? -15.157 -16.402 -51.225 1.00 40.97  ? 69  PRO A CB  1 
ATOM   549   C CG  . PRO A 1 69  ? -13.922 -17.149 -50.744 1.00 45.06  ? 69  PRO A CG  1 
ATOM   550   C CD  . PRO A 1 69  ? -14.321 -17.766 -49.414 1.00 40.80  ? 69  PRO A CD  1 
ATOM   551   N N   . GLU A 1 70  ? -18.130 -16.955 -50.027 1.00 42.25  ? 70  GLU A N   1 
ATOM   552   C CA  . GLU A 1 70  ? -19.582 -16.876 -50.121 1.00 42.89  ? 70  GLU A CA  1 
ATOM   553   C C   . GLU A 1 70  ? -20.177 -16.011 -49.006 1.00 48.72  ? 70  GLU A C   1 
ATOM   554   O O   . GLU A 1 70  ? -21.086 -15.213 -49.266 1.00 48.92  ? 70  GLU A O   1 
ATOM   555   C CB  . GLU A 1 70  ? -20.211 -18.264 -50.107 1.00 49.98  ? 70  GLU A CB  1 
ATOM   556   C CG  . GLU A 1 70  ? -19.931 -19.097 -51.353 1.00 57.04  ? 70  GLU A CG  1 
ATOM   557   C CD  . GLU A 1 70  ? -20.746 -20.389 -51.419 1.00 61.11  ? 70  GLU A CD  1 
ATOM   558   O OE1 . GLU A 1 70  ? -21.590 -20.512 -52.337 1.00 69.78  ? 70  GLU A OE1 1 
ATOM   559   O OE2 . GLU A 1 70  ? -20.571 -21.263 -50.537 1.00 50.24  ? 70  GLU A OE2 1 
ATOM   560   N N   . LEU A 1 71  ? -19.674 -16.187 -47.765 1.00 38.91  ? 71  LEU A N   1 
ATOM   561   C CA  . LEU A 1 71  ? -20.259 -15.563 -46.590 1.00 35.65  ? 71  LEU A CA  1 
ATOM   562   C C   . LEU A 1 71  ? -19.734 -14.147 -46.380 1.00 35.61  ? 71  LEU A C   1 
ATOM   563   O O   . LEU A 1 71  ? -20.400 -13.330 -45.768 1.00 34.89  ? 71  LEU A O   1 
ATOM   564   C CB  . LEU A 1 71  ? -19.909 -16.412 -45.369 1.00 38.24  ? 71  LEU A CB  1 
ATOM   565   C CG  . LEU A 1 71  ? -20.463 -17.830 -45.375 1.00 40.13  ? 71  LEU A CG  1 
ATOM   566   C CD1 . LEU A 1 71  ? -19.926 -18.620 -44.192 1.00 38.78  ? 71  LEU A CD1 1 
ATOM   567   C CD2 . LEU A 1 71  ? -21.980 -17.793 -45.358 1.00 38.92  ? 71  LEU A CD2 1 
ATOM   568   N N   . ARG A 1 72  ? -18.516 -13.869 -46.827 1.00 35.84  ? 72  ARG A N   1 
ATOM   569   C CA  . ARG A 1 72  ? -17.924 -12.564 -46.590 1.00 44.41  ? 72  ARG A CA  1 
ATOM   570   C C   . ARG A 1 72  ? -18.286 -11.607 -47.734 1.00 47.92  ? 72  ARG A C   1 
ATOM   571   O O   . ARG A 1 72  ? -18.642 -10.451 -47.505 1.00 43.22  ? 72  ARG A O   1 
ATOM   572   C CB  . ARG A 1 72  ? -16.415 -12.747 -46.413 1.00 37.86  ? 72  ARG A CB  1 
ATOM   573   C CG  . ARG A 1 72  ? -15.696 -11.441 -46.168 1.00 40.05  ? 72  ARG A CG  1 
ATOM   574   C CD  . ARG A 1 72  ? -14.263 -11.671 -45.788 1.00 38.80  ? 72  ARG A CD  1 
ATOM   575   N NE  . ARG A 1 72  ? -13.693 -10.366 -45.613 1.00 39.86  ? 72  ARG A NE  1 
ATOM   576   C CZ  . ARG A 1 72  ? -13.040 -9.727  -46.561 1.00 46.23  ? 72  ARG A CZ  1 
ATOM   577   N NH1 . ARG A 1 72  ? -12.938 -10.286 -47.754 1.00 47.22  ? 72  ARG A NH1 1 
ATOM   578   N NH2 . ARG A 1 72  ? -12.501 -8.546  -46.312 1.00 43.12  ? 72  ARG A NH2 1 
ATOM   579   N N   . GLU A 1 73  ? -18.157 -12.087 -48.970 1.00 52.27  ? 73  GLU A N   1 
ATOM   580   C CA  . GLU A 1 73  ? -18.351 -11.253 -50.153 1.00 58.99  ? 73  GLU A CA  1 
ATOM   581   C C   . GLU A 1 73  ? -19.522 -11.766 -50.979 1.00 56.07  ? 73  GLU A C   1 
ATOM   582   O O   . GLU A 1 73  ? -20.421 -11.016 -51.323 1.00 58.42  ? 73  GLU A O   1 
ATOM   583   C CB  . GLU A 1 73  ? -17.133 -11.318 -51.082 1.00 53.19  ? 73  GLU A CB  1 
ATOM   584   C CG  . GLU A 1 73  ? -15.824 -10.965 -50.404 1.00 68.12  ? 73  GLU A CG  1 
ATOM   585   C CD  . GLU A 1 73  ? -14.763 -10.347 -51.300 1.00 67.86  ? 73  GLU A CD  1 
ATOM   586   O OE1 . GLU A 1 73  ? -13.696 -9.960  -50.771 1.00 74.09  ? 73  GLU A OE1 1 
ATOM   587   O OE2 . GLU A 1 73  ? -15.004 -10.239 -52.515 1.00 81.45  ? 73  GLU A OE2 1 
ATOM   588   N N   . GLY A 1 74  ? -19.434 -13.069 -51.271 1.00 69.87  ? 74  GLY A N   1 
ATOM   589   C CA  . GLY A 1 74  ? -19.968 -13.704 -52.459 1.00 57.38  ? 74  GLY A CA  1 
ATOM   590   C C   . GLY A 1 74  ? -21.472 -13.780 -52.352 1.00 64.61  ? 74  GLY A C   1 
ATOM   591   O O   . GLY A 1 74  ? -22.080 -12.967 -51.656 1.00 75.20  ? 74  GLY A O   1 
ATOM   592   N N   . PRO A 1 75  ? -22.095 -14.776 -53.007 1.00 63.23  ? 75  PRO A N   1 
ATOM   593   C CA  . PRO A 1 75  ? -23.550 -14.788 -53.139 1.00 52.65  ? 75  PRO A CA  1 
ATOM   594   C C   . PRO A 1 75  ? -24.346 -15.153 -51.887 1.00 52.28  ? 75  PRO A C   1 
ATOM   595   O O   . PRO A 1 75  ? -25.574 -15.190 -51.928 1.00 49.30  ? 75  PRO A O   1 
ATOM   596   C CB  . PRO A 1 75  ? -23.767 -15.820 -54.263 1.00 57.05  ? 75  PRO A CB  1 
ATOM   597   C CG  . PRO A 1 75  ? -22.579 -16.756 -54.159 1.00 56.57  ? 75  PRO A CG  1 
ATOM   598   C CD  . PRO A 1 75  ? -21.424 -15.881 -53.716 1.00 55.99  ? 75  PRO A CD  1 
ATOM   599   N N   . HIS A 1 76  ? -23.684 -15.405 -50.750 1.00 50.87  ? 76  HIS A N   1 
ATOM   600   C CA  . HIS A 1 76  ? -24.447 -15.684 -49.537 1.00 48.90  ? 76  HIS A CA  1 
ATOM   601   C C   . HIS A 1 76  ? -23.909 -14.849 -48.375 1.00 48.59  ? 76  HIS A C   1 
ATOM   602   O O   . HIS A 1 76  ? -23.457 -15.387 -47.371 1.00 41.12  ? 76  HIS A O   1 
ATOM   603   C CB  . HIS A 1 76  ? -24.426 -17.186 -49.233 1.00 52.58  ? 76  HIS A CB  1 
ATOM   604   C CG  . HIS A 1 76  ? -24.976 -18.036 -50.335 1.00 56.23  ? 76  HIS A CG  1 
ATOM   605   N ND1 . HIS A 1 76  ? -26.313 -18.058 -50.681 1.00 52.84  ? 76  HIS A ND1 1 
ATOM   606   C CD2 . HIS A 1 76  ? -24.356 -18.893 -51.156 1.00 55.13  ? 76  HIS A CD2 1 
ATOM   607   C CE1 . HIS A 1 76  ? -26.483 -18.917 -51.672 1.00 54.95  ? 76  HIS A CE1 1 
ATOM   608   N NE2 . HIS A 1 76  ? -25.309 -19.427 -51.983 1.00 57.28  ? 76  HIS A NE2 1 
ATOM   609   N N   . LYS A 1 77  ? -23.947 -13.531 -48.531 1.00 44.17  ? 77  LYS A N   1 
ATOM   610   C CA  . LYS A 1 77  ? -23.236 -12.640 -47.631 1.00 45.52  ? 77  LYS A CA  1 
ATOM   611   C C   . LYS A 1 77  ? -24.014 -12.545 -46.322 1.00 45.31  ? 77  LYS A C   1 
ATOM   612   O O   . LYS A 1 77  ? -25.188 -12.225 -46.311 1.00 35.97  ? 77  LYS A O   1 
ATOM   613   C CB  . LYS A 1 77  ? -22.974 -11.277 -48.283 1.00 45.63  ? 77  LYS A CB  1 
ATOM   614   C CG  . LYS A 1 77  ? -22.159 -10.302 -47.438 1.00 40.11  ? 77  LYS A CG  1 
ATOM   615   C CD  . LYS A 1 77  ? -21.824 -9.028  -48.167 1.00 43.75  ? 77  LYS A CD  1 
ATOM   616   C CE  . LYS A 1 77  ? -21.206 -7.976  -47.284 1.00 47.47  ? 77  LYS A CE  1 
ATOM   617   N NZ  . LYS A 1 77  ? -19.934 -8.480  -46.714 1.00 52.70  ? 77  LYS A NZ  1 
ATOM   618   N N   . LEU A 1 78  ? -23.322 -12.842 -45.212 1.00 42.32  ? 78  LEU A N   1 
ATOM   619   C CA  . LEU A 1 78  ? -23.919 -12.782 -43.895 1.00 38.65  ? 78  LEU A CA  1 
ATOM   620   C C   . LEU A 1 78  ? -24.150 -11.330 -43.535 1.00 34.42  ? 78  LEU A C   1 
ATOM   621   O O   . LEU A 1 78  ? -23.476 -10.462 -44.068 1.00 31.66  ? 78  LEU A O   1 
ATOM   622   C CB  . LEU A 1 78  ? -22.955 -13.412 -42.884 1.00 39.31  ? 78  LEU A CB  1 
ATOM   623   C CG  . LEU A 1 78  ? -22.863 -14.928 -42.938 1.00 35.81  ? 78  LEU A CG  1 
ATOM   624   C CD1 . LEU A 1 78  ? -21.689 -15.442 -42.114 1.00 40.27  ? 78  LEU A CD1 1 
ATOM   625   C CD2 . LEU A 1 78  ? -24.157 -15.548 -42.488 1.00 35.38  ? 78  LEU A CD2 1 
ATOM   626   N N   . PRO A 1 79  ? -25.038 -11.037 -42.566 1.00 34.36  ? 79  PRO A N   1 
ATOM   627   C CA  . PRO A 1 79  ? -25.207 -9.674  -42.072 1.00 38.42  ? 79  PRO A CA  1 
ATOM   628   C C   . PRO A 1 79  ? -23.967 -9.046  -41.439 1.00 41.17  ? 79  PRO A C   1 
ATOM   629   O O   . PRO A 1 79  ? -23.175 -9.710  -40.754 1.00 37.79  ? 79  PRO A O   1 
ATOM   630   C CB  . PRO A 1 79  ? -26.280 -9.815  -40.992 1.00 34.82  ? 79  PRO A CB  1 
ATOM   631   C CG  . PRO A 1 79  ? -27.043 -11.033 -41.446 1.00 37.09  ? 79  PRO A CG  1 
ATOM   632   C CD  . PRO A 1 79  ? -26.000 -11.969 -41.999 1.00 34.40  ? 79  PRO A CD  1 
ATOM   633   N N   . THR A 1 80  ? -23.895 -7.731  -41.621 1.00 39.45  ? 80  THR A N   1 
ATOM   634   C CA  . THR A 1 80  ? -22.799 -6.894  -41.186 1.00 38.05  ? 80  THR A CA  1 
ATOM   635   C C   . THR A 1 80  ? -23.341 -5.890  -40.185 1.00 39.91  ? 80  THR A C   1 
ATOM   636   O O   . THR A 1 80  ? -24.550 -5.809  -39.987 1.00 38.16  ? 80  THR A O   1 
ATOM   637   C CB  . THR A 1 80  ? -22.217 -6.157  -42.388 1.00 43.83  ? 80  THR A CB  1 
ATOM   638   O OG1 . THR A 1 80  ? -23.178 -5.150  -42.720 1.00 38.93  ? 80  THR A OG1 1 
ATOM   639   C CG2 . THR A 1 80  ? -21.931 -7.080  -43.548 1.00 38.32  ? 80  THR A CG2 1 
ATOM   640   N N   . ALA A 1 81  ? -22.442 -5.122  -39.561 1.00 38.16  ? 81  ALA A N   1 
ATOM   641   C CA  . ALA A 1 81  ? -22.868 -4.028  -38.714 1.00 44.46  ? 81  ALA A CA  1 
ATOM   642   C C   . ALA A 1 81  ? -23.418 -2.929  -39.615 1.00 42.79  ? 81  ALA A C   1 
ATOM   643   O O   . ALA A 1 81  ? -23.107 -2.902  -40.812 1.00 41.00  ? 81  ALA A O   1 
ATOM   644   C CB  . ALA A 1 81  ? -21.697 -3.519  -37.896 1.00 43.85  ? 81  ALA A CB  1 
ATOM   645   N N   . GLU A 1 82  ? -24.145 -1.995  -39.000 1.00 44.27  ? 82  GLU A N   1 
ATOM   646   C CA  . GLU A 1 82  ? -24.607 -0.788  -39.674 1.00 50.11  ? 82  GLU A CA  1 
ATOM   647   C C   . GLU A 1 82  ? -23.421 -0.013  -40.256 1.00 48.33  ? 82  GLU A C   1 
ATOM   648   O O   . GLU A 1 82  ? -22.533 0.433   -39.532 1.00 57.50  ? 82  GLU A O   1 
ATOM   649   C CB  . GLU A 1 82  ? -25.417 0.060   -38.691 1.00 59.05  ? 82  GLU A CB  1 
ATOM   650   C CG  . GLU A 1 82  ? -26.401 0.996   -39.390 1.00 72.05  ? 82  GLU A CG  1 
ATOM   651   C CD  . GLU A 1 82  ? -27.242 1.874   -38.473 1.00 79.55  ? 82  GLU A CD  1 
ATOM   652   O OE1 . GLU A 1 82  ? -27.296 3.099   -38.716 1.00 94.68  ? 82  GLU A OE1 1 
ATOM   653   O OE2 . GLU A 1 82  ? -27.842 1.337   -37.515 1.00 80.41  ? 82  GLU A OE2 1 
ATOM   654   N N   . GLY A 1 83  ? -23.383 0.085   -41.585 1.00 45.78  ? 83  GLY A N   1 
ATOM   655   C CA  . GLY A 1 83  ? -22.305 0.741   -42.313 1.00 47.67  ? 83  GLY A CA  1 
ATOM   656   C C   . GLY A 1 83  ? -21.035 -0.098  -42.463 1.00 46.65  ? 83  GLY A C   1 
ATOM   657   O O   . GLY A 1 83  ? -20.008 0.433   -42.878 1.00 49.51  ? 83  GLY A O   1 
ATOM   658   N N   . GLY A 1 84  ? -21.095 -1.395  -42.106 1.00 50.57  ? 84  GLY A N   1 
ATOM   659   C CA  . GLY A 1 84  ? -19.934 -2.269  -42.152 1.00 46.50  ? 84  GLY A CA  1 
ATOM   660   C C   . GLY A 1 84  ? -19.923 -3.187  -43.373 1.00 48.52  ? 84  GLY A C   1 
ATOM   661   O O   . GLY A 1 84  ? -20.941 -3.352  -44.028 1.00 58.22  ? 84  GLY A O   1 
ATOM   662   N N   . PHE A 1 85  ? -18.759 -3.787  -43.653 1.00 42.16  ? 85  PHE A N   1 
ATOM   663   C CA  . PHE A 1 85  ? -18.592 -4.787  -44.690 1.00 44.02  ? 85  PHE A CA  1 
ATOM   664   C C   . PHE A 1 85  ? -18.349 -6.187  -44.104 1.00 45.51  ? 85  PHE A C   1 
ATOM   665   O O   . PHE A 1 85  ? -18.779 -7.197  -44.667 1.00 43.89  ? 85  PHE A O   1 
ATOM   666   C CB  . PHE A 1 85  ? -17.416 -4.432  -45.604 1.00 46.91  ? 85  PHE A CB  1 
ATOM   667   C CG  . PHE A 1 85  ? -17.190 -5.464  -46.678 1.00 50.77  ? 85  PHE A CG  1 
ATOM   668   C CD1 . PHE A 1 85  ? -18.036 -5.538  -47.778 1.00 53.16  ? 85  PHE A CD1 1 
ATOM   669   C CD2 . PHE A 1 85  ? -16.186 -6.419  -46.555 1.00 53.01  ? 85  PHE A CD2 1 
ATOM   670   C CE1 . PHE A 1 85  ? -17.844 -6.514  -48.749 1.00 51.76  ? 85  PHE A CE1 1 
ATOM   671   C CE2 . PHE A 1 85  ? -15.993 -7.387  -47.532 1.00 48.17  ? 85  PHE A CE2 1 
ATOM   672   C CZ  . PHE A 1 85  ? -16.827 -7.437  -48.622 1.00 51.34  ? 85  PHE A CZ  1 
ATOM   673   N N   . GLU A 1 86  ? -17.657 -6.263  -42.966 1.00 38.22  ? 86  GLU A N   1 
ATOM   674   C CA  . GLU A 1 86  ? -17.241 -7.534  -42.402 1.00 36.51  ? 86  GLU A CA  1 
ATOM   675   C C   . GLU A 1 86  ? -18.424 -8.235  -41.755 1.00 30.78  ? 86  GLU A C   1 
ATOM   676   O O   . GLU A 1 86  ? -19.278 -7.593  -41.156 1.00 36.54  ? 86  GLU A O   1 
ATOM   677   C CB  . GLU A 1 86  ? -16.077 -7.295  -41.439 1.00 39.20  ? 86  GLU A CB  1 
ATOM   678   C CG  . GLU A 1 86  ? -14.882 -6.700  -42.149 1.00 37.97  ? 86  GLU A CG  1 
ATOM   679   C CD  . GLU A 1 86  ? -14.336 -7.572  -43.265 1.00 44.69  ? 86  GLU A CD  1 
ATOM   680   O OE1 . GLU A 1 86  ? -13.425 -7.091  -43.994 1.00 42.43  ? 86  GLU A OE1 1 
ATOM   681   O OE2 . GLU A 1 86  ? -14.788 -8.754  -43.365 1.00 43.24  ? 86  GLU A OE2 1 
ATOM   682   N N   . PRO A 1 87  ? -18.520 -9.576  -41.901 1.00 32.70  ? 87  PRO A N   1 
ATOM   683   C CA  . PRO A 1 87  ? -19.618 -10.354 -41.349 1.00 33.25  ? 87  PRO A CA  1 
ATOM   684   C C   . PRO A 1 87  ? -19.547 -10.410 -39.828 1.00 35.55  ? 87  PRO A C   1 
ATOM   685   O O   . PRO A 1 87  ? -18.469 -10.558 -39.263 1.00 35.28  ? 87  PRO A O   1 
ATOM   686   C CB  . PRO A 1 87  ? -19.437 -11.755 -41.928 1.00 36.87  ? 87  PRO A CB  1 
ATOM   687   C CG  . PRO A 1 87  ? -17.983 -11.837 -42.271 1.00 37.35  ? 87  PRO A CG  1 
ATOM   688   C CD  . PRO A 1 87  ? -17.526 -10.427 -42.563 1.00 35.08  ? 87  PRO A CD  1 
ATOM   689   N N   . LEU A 1 88  ? -20.714 -10.274 -39.200 1.00 33.95  ? 88  LEU A N   1 
ATOM   690   C CA  . LEU A 1 88  ? -20.822 -10.354 -37.763 1.00 37.04  ? 88  LEU A CA  1 
ATOM   691   C C   . LEU A 1 88  ? -20.693 -11.813 -37.344 1.00 38.88  ? 88  LEU A C   1 
ATOM   692   O O   . LEU A 1 88  ? -21.416 -12.692 -37.840 1.00 32.66  ? 88  LEU A O   1 
ATOM   693   C CB  . LEU A 1 88  ? -22.163 -9.780  -37.304 1.00 36.53  ? 88  LEU A CB  1 
ATOM   694   C CG  . LEU A 1 88  ? -22.308 -8.263  -37.403 1.00 41.10  ? 88  LEU A CG  1 
ATOM   695   C CD1 . LEU A 1 88  ? -23.585 -7.822  -36.726 1.00 39.00  ? 88  LEU A CD1 1 
ATOM   696   C CD2 . LEU A 1 88  ? -21.114 -7.531  -36.777 1.00 42.97  ? 88  LEU A CD2 1 
ATOM   697   N N   . PRO A 1 89  ? -19.811 -12.117 -36.369 1.00 36.14  ? 89  PRO A N   1 
ATOM   698   C CA  . PRO A 1 89  ? -19.721 -13.485 -35.858 1.00 33.08  ? 89  PRO A CA  1 
ATOM   699   C C   . PRO A 1 89  ? -20.998 -14.070 -35.268 1.00 30.19  ? 89  PRO A C   1 
ATOM   700   O O   . PRO A 1 89  ? -21.157 -15.278 -35.300 1.00 32.93  ? 89  PRO A O   1 
ATOM   701   C CB  . PRO A 1 89  ? -18.593 -13.421 -34.818 1.00 35.40  ? 89  PRO A CB  1 
ATOM   702   C CG  . PRO A 1 89  ? -18.400 -11.952 -34.531 1.00 38.30  ? 89  PRO A CG  1 
ATOM   703   C CD  . PRO A 1 89  ? -18.811 -11.214 -35.782 1.00 34.32  ? 89  PRO A CD  1 
ATOM   704   N N   . GLU A 1 90  ? -21.893 -13.231 -34.733 1.00 32.75  ? 90  GLU A N   1 
ATOM   705   C CA  . GLU A 1 90  ? -23.204 -13.647 -34.244 1.00 35.72  ? 90  GLU A CA  1 
ATOM   706   C C   . GLU A 1 90  ? -24.034 -14.394 -35.313 1.00 35.83  ? 90  GLU A C   1 
ATOM   707   O O   . GLU A 1 90  ? -24.771 -15.331 -35.000 1.00 32.22  ? 90  GLU A O   1 
ATOM   708   C CB  . GLU A 1 90  ? -24.026 -12.439 -33.786 1.00 35.54  ? 90  GLU A CB  1 
ATOM   709   C CG  . GLU A 1 90  ? -23.492 -11.703 -32.561 1.00 39.62  ? 90  GLU A CG  1 
ATOM   710   C CD  . GLU A 1 90  ? -22.630 -10.466 -32.782 1.00 37.74  ? 90  GLU A CD  1 
ATOM   711   O OE1 . GLU A 1 90  ? -22.851 -9.469  -32.061 1.00 31.66  ? 90  GLU A OE1 1 
ATOM   712   O OE2 . GLU A 1 90  ? -21.691 -10.502 -33.630 1.00 35.23  ? 90  GLU A OE2 1 
ATOM   713   N N   . GLY A 1 91  ? -23.969 -13.957 -36.572 1.00 38.96  ? 91  GLY A N   1 
ATOM   714   C CA  . GLY A 1 91  ? -24.718 -14.603 -37.643 1.00 37.72  ? 91  GLY A CA  1 
ATOM   715   C C   . GLY A 1 91  ? -24.043 -15.901 -38.083 1.00 35.73  ? 91  GLY A C   1 
ATOM   716   O O   . GLY A 1 91  ? -24.702 -16.908 -38.394 1.00 33.55  ? 91  GLY A O   1 
ATOM   717   N N   . LEU A 1 92  ? -22.712 -15.883 -38.086 1.00 33.63  ? 92  LEU A N   1 
ATOM   718   C CA  . LEU A 1 92  ? -21.979 -17.115 -38.302 1.00 35.08  ? 92  LEU A CA  1 
ATOM   719   C C   . LEU A 1 92  ? -22.354 -18.156 -37.252 1.00 33.48  ? 92  LEU A C   1 
ATOM   720   O O   . LEU A 1 92  ? -22.516 -19.317 -37.594 1.00 32.14  ? 92  LEU A O   1 
ATOM   721   C CB  . LEU A 1 92  ? -20.477 -16.868 -38.321 1.00 39.84  ? 92  LEU A CB  1 
ATOM   722   C CG  . LEU A 1 92  ? -19.649 -18.145 -38.426 1.00 42.67  ? 92  LEU A CG  1 
ATOM   723   C CD1 . LEU A 1 92  ? -19.998 -18.920 -39.685 1.00 43.08  ? 92  LEU A CD1 1 
ATOM   724   C CD2 . LEU A 1 92  ? -18.172 -17.838 -38.395 1.00 47.34  ? 92  LEU A CD2 1 
ATOM   725   N N   . TRP A 1 93  ? -22.498 -17.773 -35.980 1.00 32.48  ? 93  TRP A N   1 
ATOM   726   C CA  . TRP A 1 93  ? -22.902 -18.734 -34.967 1.00 29.70  ? 93  TRP A CA  1 
ATOM   727   C C   . TRP A 1 93  ? -24.282 -19.315 -35.286 1.00 31.38  ? 93  TRP A C   1 
ATOM   728   O O   . TRP A 1 93  ? -24.535 -20.489 -35.054 1.00 29.98  ? 93  TRP A O   1 
ATOM   729   C CB  . TRP A 1 93  ? -22.956 -18.072 -33.610 1.00 28.55  ? 93  TRP A CB  1 
ATOM   730   C CG  . TRP A 1 93  ? -22.966 -18.994 -32.439 1.00 27.11  ? 93  TRP A CG  1 
ATOM   731   C CD1 . TRP A 1 93  ? -22.029 -19.947 -32.119 1.00 28.52  ? 93  TRP A CD1 1 
ATOM   732   C CD2 . TRP A 1 93  ? -23.908 -18.977 -31.361 1.00 28.82  ? 93  TRP A CD2 1 
ATOM   733   N NE1 . TRP A 1 93  ? -22.341 -20.529 -30.925 1.00 27.68  ? 93  TRP A NE1 1 
ATOM   734   C CE2 . TRP A 1 93  ? -23.472 -19.944 -30.422 1.00 26.52  ? 93  TRP A CE2 1 
ATOM   735   C CE3 . TRP A 1 93  ? -25.036 -18.202 -31.066 1.00 31.32  ? 93  TRP A CE3 1 
ATOM   736   C CZ2 . TRP A 1 93  ? -24.132 -20.171 -29.221 1.00 29.71  ? 93  TRP A CZ2 1 
ATOM   737   C CZ3 . TRP A 1 93  ? -25.714 -18.453 -29.884 1.00 33.42  ? 93  TRP A CZ3 1 
ATOM   738   C CH2 . TRP A 1 93  ? -25.264 -19.419 -28.970 1.00 29.77  ? 93  TRP A CH2 1 
ATOM   739   N N   . TYR A 1 94  ? -25.222 -18.464 -35.703 1.00 35.60  ? 94  TYR A N   1 
ATOM   740   C CA  . TYR A 1 94  ? -26.557 -18.931 -36.077 1.00 35.48  ? 94  TYR A CA  1 
ATOM   741   C C   . TYR A 1 94  ? -26.449 -20.003 -37.157 1.00 31.22  ? 94  TYR A C   1 
ATOM   742   O O   . TYR A 1 94  ? -27.045 -21.052 -37.008 1.00 31.55  ? 94  TYR A O   1 
ATOM   743   C CB  . TYR A 1 94  ? -27.443 -17.781 -36.565 1.00 36.79  ? 94  TYR A CB  1 
ATOM   744   C CG  . TYR A 1 94  ? -28.864 -18.156 -36.897 1.00 35.69  ? 94  TYR A CG  1 
ATOM   745   C CD1 . TYR A 1 94  ? -29.217 -18.726 -38.118 1.00 41.72  ? 94  TYR A CD1 1 
ATOM   746   C CD2 . TYR A 1 94  ? -29.879 -17.890 -36.000 1.00 35.95  ? 94  TYR A CD2 1 
ATOM   747   C CE1 . TYR A 1 94  ? -30.545 -19.046 -38.407 1.00 42.60  ? 94  TYR A CE1 1 
ATOM   748   C CE2 . TYR A 1 94  ? -31.205 -18.165 -36.285 1.00 44.85  ? 94  TYR A CE2 1 
ATOM   749   C CZ  . TYR A 1 94  ? -31.546 -18.745 -37.493 1.00 42.99  ? 94  TYR A CZ  1 
ATOM   750   O OH  . TYR A 1 94  ? -32.886 -19.026 -37.676 1.00 45.42  ? 94  TYR A OH  1 
ATOM   751   N N   . LEU A 1 95  ? -25.636 -19.743 -38.192 1.00 30.27  ? 95  LEU A N   1 
ATOM   752   C CA  . LEU A 1 95  ? -25.392 -20.684 -39.274 1.00 32.46  ? 95  LEU A CA  1 
ATOM   753   C C   . LEU A 1 95  ? -24.793 -21.985 -38.764 1.00 34.02  ? 95  LEU A C   1 
ATOM   754   O O   . LEU A 1 95  ? -25.220 -23.057 -39.185 1.00 33.22  ? 95  LEU A O   1 
ATOM   755   C CB  . LEU A 1 95  ? -24.463 -20.042 -40.307 1.00 31.80  ? 95  LEU A CB  1 
ATOM   756   C CG  . LEU A 1 95  ? -23.956 -20.965 -41.401 1.00 31.71  ? 95  LEU A CG  1 
ATOM   757   C CD1 . LEU A 1 95  ? -25.088 -21.572 -42.207 1.00 35.35  ? 95  LEU A CD1 1 
ATOM   758   C CD2 . LEU A 1 95  ? -23.037 -20.203 -42.304 1.00 33.78  ? 95  LEU A CD2 1 
ATOM   759   N N   . LEU A 1 96  ? -23.781 -21.898 -37.884 1.00 32.61  ? 96  LEU A N   1 
ATOM   760   C CA  . LEU A 1 96  ? -23.126 -23.095 -37.366 1.00 29.60  ? 96  LEU A CA  1 
ATOM   761   C C   . LEU A 1 96  ? -24.135 -23.957 -36.625 1.00 28.27  ? 96  LEU A C   1 
ATOM   762   O O   . LEU A 1 96  ? -24.091 -25.187 -36.730 1.00 31.66  ? 96  LEU A O   1 
ATOM   763   C CB  . LEU A 1 96  ? -21.971 -22.728 -36.427 1.00 30.84  ? 96  LEU A CB  1 
ATOM   764   C CG  . LEU A 1 96  ? -20.799 -21.982 -37.028 1.00 30.60  ? 96  LEU A CG  1 
ATOM   765   C CD1 . LEU A 1 96  ? -19.672 -21.876 -36.013 1.00 33.65  ? 96  LEU A CD1 1 
ATOM   766   C CD2 . LEU A 1 96  ? -20.278 -22.671 -38.281 1.00 34.71  ? 96  LEU A CD2 1 
ATOM   767   N N   . LEU A 1 97  ? -25.018 -23.321 -35.844 1.00 28.16  ? 97  LEU A N   1 
ATOM   768   C CA  . LEU A 1 97  ? -25.952 -24.079 -35.017 1.00 32.53  ? 97  LEU A CA  1 
ATOM   769   C C   . LEU A 1 97  ? -27.071 -24.718 -35.854 1.00 34.50  ? 97  LEU A C   1 
ATOM   770   O O   . LEU A 1 97  ? -27.416 -25.881 -35.640 1.00 33.51  ? 97  LEU A O   1 
ATOM   771   C CB  . LEU A 1 97  ? -26.523 -23.147 -33.940 1.00 33.02  ? 97  LEU A CB  1 
ATOM   772   C CG  . LEU A 1 97  ? -25.701 -23.069 -32.649 1.00 34.67  ? 97  LEU A CG  1 
ATOM   773   C CD1 . LEU A 1 97  ? -26.281 -22.059 -31.660 1.00 34.13  ? 97  LEU A CD1 1 
ATOM   774   C CD2 . LEU A 1 97  ? -25.624 -24.441 -32.002 1.00 33.94  ? 97  LEU A CD2 1 
ATOM   775   N N   . THR A 1 98  ? -27.627 -23.959 -36.812 1.00 35.23  ? 98  THR A N   1 
ATOM   776   C CA  . THR A 1 98  ? -28.847 -24.337 -37.512 1.00 36.27  ? 98  THR A CA  1 
ATOM   777   C C   . THR A 1 98  ? -28.575 -24.931 -38.892 1.00 37.27  ? 98  THR A C   1 
ATOM   778   O O   . THR A 1 98  ? -29.433 -25.639 -39.432 1.00 38.13  ? 98  THR A O   1 
ATOM   779   C CB  . THR A 1 98  ? -29.790 -23.153 -37.720 1.00 35.65  ? 98  THR A CB  1 
ATOM   780   O OG1 . THR A 1 98  ? -29.119 -22.145 -38.493 1.00 36.63  ? 98  THR A OG1 1 
ATOM   781   C CG2 . THR A 1 98  ? -30.311 -22.589 -36.416 1.00 41.19  ? 98  THR A CG2 1 
ATOM   782   N N   . GLY A 1 99  ? -27.430 -24.595 -39.485 1.00 38.11  ? 99  GLY A N   1 
ATOM   783   C CA  . GLY A 1 99  ? -27.162 -24.917 -40.876 1.00 37.36  ? 99  GLY A CA  1 
ATOM   784   C C   . GLY A 1 99  ? -27.880 -23.984 -41.870 1.00 37.64  ? 99  GLY A C   1 
ATOM   785   O O   . GLY A 1 99  ? -27.712 -24.174 -43.059 1.00 40.64  ? 99  GLY A O   1 
ATOM   786   N N   . GLU A 1 100 ? -28.603 -22.964 -41.390 1.00 34.30  ? 100 GLU A N   1 
ATOM   787   C CA  . GLU A 1 100 ? -29.392 -22.035 -42.193 1.00 36.76  ? 100 GLU A CA  1 
ATOM   788   C C   . GLU A 1 100 ? -28.817 -20.621 -42.105 1.00 40.21  ? 100 GLU A C   1 
ATOM   789   O O   . GLU A 1 100 ? -28.338 -20.229 -41.049 1.00 41.36  ? 100 GLU A O   1 
ATOM   790   C CB  . GLU A 1 100 ? -30.822 -22.029 -41.658 1.00 40.44  ? 100 GLU A CB  1 
ATOM   791   C CG  . GLU A 1 100 ? -31.521 -23.378 -41.790 1.00 46.24  ? 100 GLU A CG  1 
ATOM   792   C CD  . GLU A 1 100 ? -32.866 -23.501 -41.084 1.00 50.23  ? 100 GLU A CD  1 
ATOM   793   O OE1 . GLU A 1 100 ? -33.553 -24.516 -41.329 1.00 46.87  ? 100 GLU A OE1 1 
ATOM   794   O OE2 . GLU A 1 100 ? -33.221 -22.595 -40.277 1.00 49.06  ? 100 GLU A OE2 1 
ATOM   795   N N   . LEU A 1 101 ? -28.827 -19.863 -43.212 1.00 39.69  ? 101 LEU A N   1 
ATOM   796   C CA  . LEU A 1 101 ? -28.311 -18.500 -43.222 1.00 39.60  ? 101 LEU A CA  1 
ATOM   797   C C   . LEU A 1 101 ? -29.265 -17.611 -42.446 1.00 40.74  ? 101 LEU A C   1 
ATOM   798   O O   . LEU A 1 101 ? -30.471 -17.729 -42.615 1.00 42.37  ? 101 LEU A O   1 
ATOM   799   C CB  . LEU A 1 101 ? -28.173 -17.996 -44.657 1.00 43.45  ? 101 LEU A CB  1 
ATOM   800   C CG  . LEU A 1 101 ? -27.143 -18.731 -45.500 1.00 45.97  ? 101 LEU A CG  1 
ATOM   801   C CD1 . LEU A 1 101 ? -27.261 -18.320 -46.955 1.00 44.29  ? 101 LEU A CD1 1 
ATOM   802   C CD2 . LEU A 1 101 ? -25.740 -18.452 -44.985 1.00 44.99  ? 101 LEU A CD2 1 
ATOM   803   N N   . PRO A 1 102 ? -28.785 -16.740 -41.530 1.00 39.52  ? 102 PRO A N   1 
ATOM   804   C CA  . PRO A 1 102 ? -29.702 -15.948 -40.706 1.00 39.35  ? 102 PRO A CA  1 
ATOM   805   C C   . PRO A 1 102 ? -30.197 -14.720 -41.465 1.00 35.36  ? 102 PRO A C   1 
ATOM   806   O O   . PRO A 1 102 ? -29.524 -14.246 -42.365 1.00 37.95  ? 102 PRO A O   1 
ATOM   807   C CB  . PRO A 1 102 ? -28.818 -15.504 -39.538 1.00 39.28  ? 102 PRO A CB  1 
ATOM   808   C CG  . PRO A 1 102 ? -27.457 -15.352 -40.199 1.00 40.92  ? 102 PRO A CG  1 
ATOM   809   C CD  . PRO A 1 102 ? -27.372 -16.489 -41.212 1.00 38.14  ? 102 PRO A CD  1 
ATOM   810   N N   . THR A 1 103 ? -31.301 -14.156 -41.007 1.00 36.14  ? 103 THR A N   1 
ATOM   811   C CA  . THR A 1 103 ? -31.715 -12.834 -41.443 1.00 43.86  ? 103 THR A CA  1 
ATOM   812   C C   . THR A 1 103 ? -31.039 -11.806 -40.556 1.00 46.63  ? 103 THR A C   1 
ATOM   813   O O   . THR A 1 103 ? -30.423 -12.176 -39.562 1.00 40.52  ? 103 THR A O   1 
ATOM   814   C CB  . THR A 1 103 ? -33.235 -12.635 -41.330 1.00 45.18  ? 103 THR A CB  1 
ATOM   815   O OG1 . THR A 1 103 ? -33.586 -12.629 -39.945 1.00 46.59  ? 103 THR A OG1 1 
ATOM   816   C CG2 . THR A 1 103 ? -34.030 -13.699 -42.055 1.00 46.09  ? 103 THR A CG2 1 
ATOM   817   N N   . GLU A 1 104 ? -31.259 -10.529 -40.876 1.00 44.87  ? 104 GLU A N   1 
ATOM   818   C CA  . GLU A 1 104 ? -30.819 -9.408  -40.066 1.00 51.98  ? 104 GLU A CA  1 
ATOM   819   C C   . GLU A 1 104 ? -31.372 -9.506  -38.649 1.00 53.25  ? 104 GLU A C   1 
ATOM   820   O O   . GLU A 1 104 ? -30.672 -9.214  -37.674 1.00 55.89  ? 104 GLU A O   1 
ATOM   821   C CB  . GLU A 1 104 ? -31.285 -8.102  -40.705 1.00 60.05  ? 104 GLU A CB  1 
ATOM   822   C CG  . GLU A 1 104 ? -30.156 -7.337  -41.354 1.00 74.45  ? 104 GLU A CG  1 
ATOM   823   C CD  . GLU A 1 104 ? -29.304 -6.592  -40.342 1.00 89.16  ? 104 GLU A CD  1 
ATOM   824   O OE1 . GLU A 1 104 ? -28.065 -6.737  -40.388 1.00 106.74 ? 104 GLU A OE1 1 
ATOM   825   O OE2 . GLU A 1 104 ? -29.888 -5.882  -39.496 1.00 105.10 ? 104 GLU A OE2 1 
ATOM   826   N N   . GLU A 1 105 ? -32.648 -9.881  -38.566 1.00 50.81  ? 105 GLU A N   1 
ATOM   827   C CA  . GLU A 1 105 ? -33.368 -9.870  -37.311 1.00 52.35  ? 105 GLU A CA  1 
ATOM   828   C C   . GLU A 1 105 ? -32.856 -11.003 -36.425 1.00 49.54  ? 105 GLU A C   1 
ATOM   829   O O   . GLU A 1 105 ? -32.750 -10.820 -35.219 1.00 43.58  ? 105 GLU A O   1 
ATOM   830   C CB  . GLU A 1 105 ? -34.871 -9.995  -37.559 1.00 60.30  ? 105 GLU A CB  1 
ATOM   831   C CG  . GLU A 1 105 ? -35.690 -10.226 -36.289 1.00 73.30  ? 105 GLU A CG  1 
ATOM   832   C CD  . GLU A 1 105 ? -36.522 -11.506 -36.307 1.00 90.10  ? 105 GLU A CD  1 
ATOM   833   O OE1 . GLU A 1 105 ? -36.137 -12.477 -35.602 1.00 93.42  ? 105 GLU A OE1 1 
ATOM   834   O OE2 . GLU A 1 105 ? -37.549 -11.547 -37.031 1.00 87.15  ? 105 GLU A OE2 1 
ATOM   835   N N   . ASP A 1 106 ? -32.566 -12.169 -37.025 1.00 43.52  ? 106 ASP A N   1 
ATOM   836   C CA  . ASP A 1 106 ? -31.977 -13.295 -36.302 1.00 46.37  ? 106 ASP A CA  1 
ATOM   837   C C   . ASP A 1 106 ? -30.681 -12.847 -35.619 1.00 43.76  ? 106 ASP A C   1 
ATOM   838   O O   . ASP A 1 106 ? -30.421 -13.189 -34.466 1.00 43.44  ? 106 ASP A O   1 
ATOM   839   C CB  . ASP A 1 106 ? -31.683 -14.472 -37.246 1.00 48.86  ? 106 ASP A CB  1 
ATOM   840   C CG  . ASP A 1 106 ? -32.912 -15.031 -37.962 1.00 49.85  ? 106 ASP A CG  1 
ATOM   841   O OD1 . ASP A 1 106 ? -34.027 -14.759 -37.478 1.00 52.63  ? 106 ASP A OD1 1 
ATOM   842   O OD2 . ASP A 1 106 ? -32.748 -15.681 -39.035 1.00 45.51  ? 106 ASP A OD2 1 
ATOM   843   N N   . VAL A 1 107 ? -29.860 -12.092 -36.357 1.00 41.01  ? 107 VAL A N   1 
ATOM   844   C CA  . VAL A 1 107 ? -28.565 -11.659 -35.868 1.00 41.10  ? 107 VAL A CA  1 
ATOM   845   C C   . VAL A 1 107 ? -28.758 -10.655 -34.734 1.00 42.23  ? 107 VAL A C   1 
ATOM   846   O O   . VAL A 1 107 ? -28.154 -10.811 -33.676 1.00 40.28  ? 107 VAL A O   1 
ATOM   847   C CB  . VAL A 1 107 ? -27.683 -11.131 -37.013 1.00 40.30  ? 107 VAL A CB  1 
ATOM   848   C CG1 . VAL A 1 107 ? -26.425 -10.473 -36.501 1.00 45.07  ? 107 VAL A CG1 1 
ATOM   849   C CG2 . VAL A 1 107 ? -27.329 -12.269 -37.954 1.00 36.14  ? 107 VAL A CG2 1 
ATOM   850   N N   . LYS A 1 108 ? -29.649 -9.679  -34.921 1.00 43.72  ? 108 LYS A N   1 
ATOM   851   C CA  . LYS A 1 108 ? -29.933 -8.703  -33.885 1.00 47.67  ? 108 LYS A CA  1 
ATOM   852   C C   . LYS A 1 108 ? -30.389 -9.378  -32.597 1.00 43.52  ? 108 LYS A C   1 
ATOM   853   O O   . LYS A 1 108 ? -30.080 -8.887  -31.518 1.00 44.18  ? 108 LYS A O   1 
ATOM   854   C CB  . LYS A 1 108 ? -31.032 -7.717  -34.281 1.00 60.10  ? 108 LYS A CB  1 
ATOM   855   C CG  . LYS A 1 108 ? -30.607 -6.585  -35.203 1.00 64.88  ? 108 LYS A CG  1 
ATOM   856   C CD  . LYS A 1 108 ? -31.548 -5.382  -35.096 1.00 76.05  ? 108 LYS A CD  1 
ATOM   857   C CE  . LYS A 1 108 ? -31.846 -4.716  -36.424 1.00 73.73  ? 108 LYS A CE  1 
ATOM   858   N NZ  . LYS A 1 108 ? -30.606 -4.425  -37.180 1.00 71.53  ? 108 LYS A NZ  1 
ATOM   859   N N   . GLU A 1 109 ? -31.185 -10.444 -32.693 1.00 36.82  ? 109 GLU A N   1 
ATOM   860   C CA  . GLU A 1 109 ? -31.642 -11.141 -31.502 1.00 37.71  ? 109 GLU A CA  1 
ATOM   861   C C   . GLU A 1 109 ? -30.466 -11.791 -30.753 1.00 40.07  ? 109 GLU A C   1 
ATOM   862   O O   . GLU A 1 109 ? -30.449 -11.803 -29.529 1.00 44.61  ? 109 GLU A O   1 
ATOM   863   C CB  . GLU A 1 109 ? -32.621 -12.256 -31.855 1.00 42.71  ? 109 GLU A CB  1 
ATOM   864   C CG  . GLU A 1 109 ? -34.036 -11.798 -32.184 1.00 51.53  ? 109 GLU A CG  1 
ATOM   865   C CD  . GLU A 1 109 ? -35.000 -12.951 -32.477 1.00 60.38  ? 109 GLU A CD  1 
ATOM   866   O OE1 . GLU A 1 109 ? -36.232 -12.780 -32.275 1.00 70.60  ? 109 GLU A OE1 1 
ATOM   867   O OE2 . GLU A 1 109 ? -34.528 -14.032 -32.925 1.00 54.49  ? 109 GLU A OE2 1 
ATOM   868   N N   . ILE A 1 110 ? -29.508 -12.377 -31.473 1.00 34.92  ? 110 ILE A N   1 
ATOM   869   C CA  . ILE A 1 110 ? -28.357 -12.981 -30.826 1.00 39.49  ? 110 ILE A CA  1 
ATOM   870   C C   . ILE A 1 110 ? -27.501 -11.878 -30.196 1.00 39.32  ? 110 ILE A C   1 
ATOM   871   O O   . ILE A 1 110 ? -27.180 -11.985 -29.022 1.00 32.98  ? 110 ILE A O   1 
ATOM   872   C CB  . ILE A 1 110 ? -27.560 -13.863 -31.798 1.00 39.17  ? 110 ILE A CB  1 
ATOM   873   C CG1 . ILE A 1 110 ? -28.388 -15.092 -32.183 1.00 39.89  ? 110 ILE A CG1 1 
ATOM   874   C CG2 . ILE A 1 110 ? -26.191 -14.236 -31.214 1.00 38.85  ? 110 ILE A CG2 1 
ATOM   875   C CD1 . ILE A 1 110 ? -27.887 -15.801 -33.409 1.00 43.54  ? 110 ILE A CD1 1 
ATOM   876   N N   . SER A 1 111 ? -27.185 -10.818 -30.948 1.00 36.73  ? 111 SER A N   1 
ATOM   877   C CA  . SER A 1 111 ? -26.486 -9.657  -30.417 1.00 40.42  ? 111 SER A CA  1 
ATOM   878   C C   . SER A 1 111 ? -27.113 -9.151  -29.118 1.00 42.47  ? 111 SER A C   1 
ATOM   879   O O   . SER A 1 111 ? -26.379 -8.819  -28.187 1.00 41.22  ? 111 SER A O   1 
ATOM   880   C CB  . SER A 1 111 ? -26.395 -8.518  -31.387 1.00 38.77  ? 111 SER A CB  1 
ATOM   881   O OG  . SER A 1 111 ? -25.484 -8.828  -32.422 1.00 37.26  ? 111 SER A OG  1 
ATOM   882   N N   . ALA A 1 112 ? -28.442 -9.051  -29.054 1.00 37.47  ? 112 ALA A N   1 
ATOM   883   C CA  . ALA A 1 112 ? -29.079 -8.497  -27.862 1.00 39.67  ? 112 ALA A CA  1 
ATOM   884   C C   . ALA A 1 112 ? -28.912 -9.457  -26.694 1.00 41.35  ? 112 ALA A C   1 
ATOM   885   O O   . ALA A 1 112 ? -28.957 -9.068  -25.534 1.00 44.53  ? 112 ALA A O   1 
ATOM   886   C CB  . ALA A 1 112 ? -30.554 -8.275  -28.099 1.00 40.88  ? 112 ALA A CB  1 
ATOM   887   N N   . GLU A 1 113 ? -28.868 -10.744 -27.014 1.00 39.02  ? 113 GLU A N   1 
ATOM   888   C CA  . GLU A 1 113 ? -28.762 -11.758 -25.983 1.00 45.14  ? 113 GLU A CA  1 
ATOM   889   C C   . GLU A 1 113 ? -27.370 -11.636 -25.362 1.00 39.31  ? 113 GLU A C   1 
ATOM   890   O O   . GLU A 1 113 ? -27.250 -11.583 -24.150 1.00 34.92  ? 113 GLU A O   1 
ATOM   891   C CB  . GLU A 1 113 ? -29.079 -13.109 -26.619 1.00 46.66  ? 113 GLU A CB  1 
ATOM   892   C CG  . GLU A 1 113 ? -29.532 -14.157 -25.665 1.00 54.72  ? 113 GLU A CG  1 
ATOM   893   C CD  . GLU A 1 113 ? -30.855 -13.836 -25.006 1.00 54.77  ? 113 GLU A CD  1 
ATOM   894   O OE1 . GLU A 1 113 ? -30.853 -13.650 -23.788 1.00 49.59  ? 113 GLU A OE1 1 
ATOM   895   O OE2 . GLU A 1 113 ? -31.867 -13.763 -25.722 1.00 63.78  ? 113 GLU A OE2 1 
ATOM   896   N N   . PHE A 1 114 ? -26.342 -11.513 -26.201 1.00 32.72  ? 114 PHE A N   1 
ATOM   897   C CA  . PHE A 1 114 ? -24.990 -11.308 -25.724 1.00 40.37  ? 114 PHE A CA  1 
ATOM   898   C C   . PHE A 1 114 ? -24.873 -10.020 -24.912 1.00 51.03  ? 114 PHE A C   1 
ATOM   899   O O   . PHE A 1 114 ? -24.268 -10.017 -23.834 1.00 46.51  ? 114 PHE A O   1 
ATOM   900   C CB  . PHE A 1 114 ? -24.011 -11.318 -26.885 1.00 38.64  ? 114 PHE A CB  1 
ATOM   901   C CG  . PHE A 1 114 ? -23.846 -12.655 -27.558 1.00 37.30  ? 114 PHE A CG  1 
ATOM   902   C CD1 . PHE A 1 114 ? -24.342 -13.821 -27.000 1.00 41.86  ? 114 PHE A CD1 1 
ATOM   903   C CD2 . PHE A 1 114 ? -23.155 -12.757 -28.747 1.00 37.10  ? 114 PHE A CD2 1 
ATOM   904   C CE1 . PHE A 1 114 ? -24.185 -15.040 -27.639 1.00 42.65  ? 114 PHE A CE1 1 
ATOM   905   C CE2 . PHE A 1 114 ? -22.983 -13.986 -29.373 1.00 40.88  ? 114 PHE A CE2 1 
ATOM   906   C CZ  . PHE A 1 114 ? -23.522 -15.122 -28.834 1.00 39.26  ? 114 PHE A CZ  1 
ATOM   907   N N   . THR A 1 115 ? -25.476 -8.940  -25.420 1.00 47.14  ? 115 THR A N   1 
ATOM   908   C CA  . THR A 1 115 ? -25.429 -7.636  -24.775 1.00 50.07  ? 115 THR A CA  1 
ATOM   909   C C   . THR A 1 115 ? -25.973 -7.696  -23.351 1.00 41.68  ? 115 THR A C   1 
ATOM   910   O O   . THR A 1 115 ? -25.374 -7.190  -22.419 1.00 48.42  ? 115 THR A O   1 
ATOM   911   C CB  . THR A 1 115 ? -26.206 -6.625  -25.632 1.00 55.78  ? 115 THR A CB  1 
ATOM   912   O OG1 . THR A 1 115 ? -25.283 -6.356  -26.683 1.00 54.93  ? 115 THR A OG1 1 
ATOM   913   C CG2 . THR A 1 115 ? -26.638 -5.367  -24.902 1.00 59.07  ? 115 THR A CG2 1 
ATOM   914   N N   . LYS A 1 116 ? -27.125 -8.327  -23.187 1.00 41.23  ? 116 LYS A N   1 
ATOM   915   C CA  . LYS A 1 116 ? -27.805 -8.359  -21.913 1.00 41.83  ? 116 LYS A CA  1 
ATOM   916   C C   . LYS A 1 116 ? -26.970 -9.199  -20.951 1.00 39.27  ? 116 LYS A C   1 
ATOM   917   O O   . LYS A 1 116 ? -26.746 -8.810  -19.817 1.00 36.62  ? 116 LYS A O   1 
ATOM   918   C CB  . LYS A 1 116 ? -29.215 -8.872  -22.203 1.00 49.72  ? 116 LYS A CB  1 
ATOM   919   C CG  . LYS A 1 116 ? -30.056 -9.384  -21.041 1.00 59.09  ? 116 LYS A CG  1 
ATOM   920   C CD  . LYS A 1 116 ? -31.225 -10.208 -21.559 1.00 65.68  ? 116 LYS A CD  1 
ATOM   921   C CE  . LYS A 1 116 ? -32.489 -10.114 -20.730 1.00 77.27  ? 116 LYS A CE  1 
ATOM   922   N NZ  . LYS A 1 116 ? -32.504 -11.107 -19.632 1.00 87.85  ? 116 LYS A NZ  1 
ATOM   923   N N   . ARG A 1 117 ? -26.468 -10.342 -21.427 1.00 33.65  ? 117 ARG A N   1 
ATOM   924   C CA  . ARG A 1 117 ? -25.862 -11.327 -20.554 1.00 31.09  ? 117 ARG A CA  1 
ATOM   925   C C   . ARG A 1 117 ? -24.439 -10.912 -20.183 1.00 30.70  ? 117 ARG A C   1 
ATOM   926   O O   . ARG A 1 117 ? -23.853 -11.445 -19.237 1.00 32.23  ? 117 ARG A O   1 
ATOM   927   C CB  . ARG A 1 117 ? -25.906 -12.675 -21.251 1.00 32.71  ? 117 ARG A CB  1 
ATOM   928   C CG  . ARG A 1 117 ? -27.280 -13.308 -21.243 1.00 33.76  ? 117 ARG A CG  1 
ATOM   929   C CD  . ARG A 1 117 ? -27.308 -14.508 -22.162 1.00 37.08  ? 117 ARG A CD  1 
ATOM   930   N NE  . ARG A 1 117 ? -28.685 -14.871 -22.465 1.00 38.21  ? 117 ARG A NE  1 
ATOM   931   C CZ  . ARG A 1 117 ? -29.356 -15.879 -21.929 1.00 39.90  ? 117 ARG A CZ  1 
ATOM   932   N NH1 . ARG A 1 117 ? -28.832 -16.625 -20.978 1.00 38.65  ? 117 ARG A NH1 1 
ATOM   933   N NH2 . ARG A 1 117 ? -30.598 -16.100 -22.312 1.00 46.76  ? 117 ARG A NH2 1 
ATOM   934   N N   . MET A 1 118 ? -23.899 -9.954  -20.930 1.00 30.08  ? 118 MET A N   1 
ATOM   935   C CA  . MET A 1 118 ? -22.573 -9.416  -20.683 1.00 35.20  ? 118 MET A CA  1 
ATOM   936   C C   . MET A 1 118 ? -22.540 -8.639  -19.369 1.00 34.23  ? 118 MET A C   1 
ATOM   937   O O   . MET A 1 118 ? -21.477 -8.431  -18.788 1.00 34.49  ? 118 MET A O   1 
ATOM   938   C CB  . MET A 1 118 ? -22.210 -8.491  -21.843 1.00 41.97  ? 118 MET A CB  1 
ATOM   939   C CG  . MET A 1 118 ? -20.767 -8.381  -22.100 1.00 47.04  ? 118 MET A CG  1 
ATOM   940   S SD  . MET A 1 118 ? -20.432 -7.608  -23.705 1.00 44.84  ? 118 MET A SD  1 
ATOM   941   C CE  . MET A 1 118 ? -20.528 -8.998  -24.844 1.00 45.79  ? 118 MET A CE  1 
ATOM   942   N N   . GLN A 1 119 ? -23.722 -8.235  -18.893 1.00 31.62  ? 119 GLN A N   1 
ATOM   943   C CA  . GLN A 1 119 ? -23.859 -7.535  -17.620 1.00 35.14  ? 119 GLN A CA  1 
ATOM   944   C C   . GLN A 1 119 ? -23.903 -8.505  -16.445 1.00 32.72  ? 119 GLN A C   1 
ATOM   945   O O   . GLN A 1 119 ? -24.067 -8.092  -15.313 1.00 37.69  ? 119 GLN A O   1 
ATOM   946   C CB  . GLN A 1 119 ? -25.166 -6.732  -17.607 1.00 40.12  ? 119 GLN A CB  1 
ATOM   947   C CG  . GLN A 1 119 ? -25.224 -5.653  -18.681 1.00 41.83  ? 119 GLN A CG  1 
ATOM   948   C CD  . GLN A 1 119 ? -24.178 -4.606  -18.402 1.00 48.61  ? 119 GLN A CD  1 
ATOM   949   O OE1 . GLN A 1 119 ? -23.851 -4.344  -17.249 1.00 51.65  ? 119 GLN A OE1 1 
ATOM   950   N NE2 . GLN A 1 119 ? -23.614 -4.013  -19.441 1.00 50.21  ? 119 GLN A NE2 1 
ATOM   951   N N   . ASN A 1 120 ? -23.798 -9.804  -16.697 1.00 30.33  ? 120 ASN A N   1 
ATOM   952   C CA  . ASN A 1 120 ? -24.100 -10.794 -15.685 1.00 34.14  ? 120 ASN A CA  1 
ATOM   953   C C   . ASN A 1 120 ? -22.871 -11.657 -15.386 1.00 27.47  ? 120 ASN A C   1 
ATOM   954   O O   . ASN A 1 120 ? -23.018 -12.786 -14.954 1.00 28.88  ? 120 ASN A O   1 
ATOM   955   C CB  . ASN A 1 120 ? -25.236 -11.738 -16.094 1.00 34.49  ? 120 ASN A CB  1 
ATOM   956   C CG  . ASN A 1 120 ? -26.548 -11.051 -16.412 1.00 39.69  ? 120 ASN A CG  1 
ATOM   957   O OD1 . ASN A 1 120 ? -27.380 -11.586 -17.155 1.00 45.79  ? 120 ASN A OD1 1 
ATOM   958   N ND2 . ASN A 1 120 ? -26.733 -9.854  -15.909 1.00 40.07  ? 120 ASN A ND2 1 
ATOM   959   N N   . VAL A 1 121 ? -21.674 -11.107 -15.491 1.00 26.80  ? 121 VAL A N   1 
ATOM   960   C CA  . VAL A 1 121 ? -20.486 -11.833 -15.082 1.00 27.87  ? 121 VAL A CA  1 
ATOM   961   C C   . VAL A 1 121 ? -20.387 -11.702 -13.569 1.00 26.83  ? 121 VAL A C   1 
ATOM   962   O O   . VAL A 1 121 ? -20.364 -10.599 -13.067 1.00 23.43  ? 121 VAL A O   1 
ATOM   963   C CB  . VAL A 1 121 ? -19.219 -11.346 -15.809 1.00 27.57  ? 121 VAL A CB  1 
ATOM   964   C CG1 . VAL A 1 121 ? -17.985 -12.076 -15.319 1.00 24.17  ? 121 VAL A CG1 1 
ATOM   965   C CG2 . VAL A 1 121 ? -19.372 -11.478 -17.320 1.00 28.89  ? 121 VAL A CG2 1 
ATOM   966   N N   . PRO A 1 122 ? -20.370 -12.809 -12.788 1.00 25.66  ? 122 PRO A N   1 
ATOM   967   C CA  . PRO A 1 122 ? -20.316 -12.694 -11.334 1.00 25.41  ? 122 PRO A CA  1 
ATOM   968   C C   . PRO A 1 122 ? -19.138 -11.872 -10.814 1.00 25.37  ? 122 PRO A C   1 
ATOM   969   O O   . PRO A 1 122 ? -18.037 -11.941 -11.324 1.00 24.18  ? 122 PRO A O   1 
ATOM   970   C CB  . PRO A 1 122 ? -20.171 -14.152 -10.885 1.00 27.75  ? 122 PRO A CB  1 
ATOM   971   C CG  . PRO A 1 122 ? -20.809 -14.954 -12.018 1.00 28.31  ? 122 PRO A CG  1 
ATOM   972   C CD  . PRO A 1 122 ? -20.349 -14.208 -13.250 1.00 28.59  ? 122 PRO A CD  1 
ATOM   973   N N   . GLN A 1 123 ? -19.357 -11.140 -9.721  1.00 25.51  ? 123 GLN A N   1 
ATOM   974   C CA  . GLN A 1 123 ? -18.293 -10.421 -9.083  1.00 25.86  ? 123 GLN A CA  1 
ATOM   975   C C   . GLN A 1 123 ? -17.151 -11.368 -8.672  1.00 23.48  ? 123 GLN A C   1 
ATOM   976   O O   . GLN A 1 123 ? -16.004 -10.974 -8.735  1.00 24.25  ? 123 GLN A O   1 
ATOM   977   C CB  . GLN A 1 123 ? -18.872 -9.610  -7.937  1.00 28.32  ? 123 GLN A CB  1 
ATOM   978   C CG  . GLN A 1 123 ? -17.814 -8.909  -7.133  1.00 32.70  ? 123 GLN A CG  1 
ATOM   979   C CD  . GLN A 1 123 ? -17.072 -7.917  -7.980  1.00 43.11  ? 123 GLN A CD  1 
ATOM   980   O OE1 . GLN A 1 123 ? -17.680 -7.114  -8.680  1.00 47.57  ? 123 GLN A OE1 1 
ATOM   981   N NE2 . GLN A 1 123 ? -15.746 -8.014  -7.964  1.00 50.60  ? 123 GLN A NE2 1 
ATOM   982   N N   . TYR A 1 124 ? -17.419 -12.613 -8.305  1.00 24.49  ? 124 TYR A N   1 
ATOM   983   C CA  . TYR A 1 124 ? -16.365 -13.475 -7.793  1.00 23.43  ? 124 TYR A CA  1 
ATOM   984   C C   . TYR A 1 124 ? -15.414 -13.907 -8.908  1.00 23.40  ? 124 TYR A C   1 
ATOM   985   O O   . TYR A 1 124 ? -14.303 -14.295 -8.619  1.00 23.37  ? 124 TYR A O   1 
ATOM   986   C CB  . TYR A 1 124 ? -16.945 -14.666 -7.023  1.00 24.13  ? 124 TYR A CB  1 
ATOM   987   C CG  . TYR A 1 124 ? -17.755 -15.612 -7.865  1.00 24.94  ? 124 TYR A CG  1 
ATOM   988   C CD1 . TYR A 1 124 ? -17.123 -16.492 -8.739  1.00 27.30  ? 124 TYR A CD1 1 
ATOM   989   C CD2 . TYR A 1 124 ? -19.135 -15.594 -7.841  1.00 24.89  ? 124 TYR A CD2 1 
ATOM   990   C CE1 . TYR A 1 124 ? -17.845 -17.322 -9.574  1.00 25.29  ? 124 TYR A CE1 1 
ATOM   991   C CE2 . TYR A 1 124 ? -19.873 -16.484 -8.614  1.00 25.82  ? 124 TYR A CE2 1 
ATOM   992   C CZ  . TYR A 1 124 ? -19.227 -17.334 -9.492  1.00 25.20  ? 124 TYR A CZ  1 
ATOM   993   O OH  . TYR A 1 124 ? -19.941 -18.157 -10.326 1.00 26.81  ? 124 TYR A OH  1 
ATOM   994   N N   . VAL A 1 125 ? -15.846 -13.878 -10.171 1.00 24.46  ? 125 VAL A N   1 
ATOM   995   C CA  . VAL A 1 125 ? -14.967 -14.163 -11.307 1.00 24.63  ? 125 VAL A CA  1 
ATOM   996   C C   . VAL A 1 125 ? -13.854 -13.118 -11.364 1.00 25.44  ? 125 VAL A C   1 
ATOM   997   O O   . VAL A 1 125 ? -12.693 -13.461 -11.503 1.00 26.70  ? 125 VAL A O   1 
ATOM   998   C CB  . VAL A 1 125 ? -15.743 -14.204 -12.636 1.00 24.20  ? 125 VAL A CB  1 
ATOM   999   C CG1 . VAL A 1 125 ? -14.821 -14.149 -13.831 1.00 26.99  ? 125 VAL A CG1 1 
ATOM   1000  C CG2 . VAL A 1 125 ? -16.633 -15.416 -12.744 1.00 27.39  ? 125 VAL A CG2 1 
ATOM   1001  N N   . PHE A 1 126 ? -14.193 -11.846 -11.128 1.00 26.63  ? 126 PHE A N   1 
ATOM   1002  C CA  . PHE A 1 126 ? -13.188 -10.793 -11.048 1.00 24.42  ? 126 PHE A CA  1 
ATOM   1003  C C   . PHE A 1 126 ? -12.290 -10.943 -9.822  1.00 26.16  ? 126 PHE A C   1 
ATOM   1004  O O   . PHE A 1 126 ? -11.093 -10.637 -9.898  1.00 25.31  ? 126 PHE A O   1 
ATOM   1005  C CB  . PHE A 1 126 ? -13.865 -9.422  -11.067 1.00 26.39  ? 126 PHE A CB  1 
ATOM   1006  C CG  . PHE A 1 126 ? -14.661 -9.208  -12.326 1.00 25.69  ? 126 PHE A CG  1 
ATOM   1007  C CD1 . PHE A 1 126 ? -14.011 -9.012  -13.539 1.00 30.49  ? 126 PHE A CD1 1 
ATOM   1008  C CD2 . PHE A 1 126 ? -16.053 -9.234  -12.307 1.00 29.12  ? 126 PHE A CD2 1 
ATOM   1009  C CE1 . PHE A 1 126 ? -14.745 -8.806  -14.703 1.00 33.66  ? 126 PHE A CE1 1 
ATOM   1010  C CE2 . PHE A 1 126 ? -16.782 -9.075  -13.476 1.00 31.77  ? 126 PHE A CE2 1 
ATOM   1011  C CZ  . PHE A 1 126 ? -16.126 -8.865  -14.670 1.00 33.28  ? 126 PHE A CZ  1 
ATOM   1012  N N   . ASP A 1 127 ? -12.863 -11.327 -8.674  1.00 26.06  ? 127 ASP A N   1 
ATOM   1013  C CA  . ASP A 1 127 ? -12.038 -11.641 -7.506  1.00 27.02  ? 127 ASP A CA  1 
ATOM   1014  C C   . ASP A 1 127 ? -11.028 -12.759 -7.819  1.00 25.50  ? 127 ASP A C   1 
ATOM   1015  O O   . ASP A 1 127 ? -9.869  -12.724 -7.393  1.00 25.93  ? 127 ASP A O   1 
ATOM   1016  C CB  . ASP A 1 127 ? -12.895 -12.082 -6.316  1.00 26.14  ? 127 ASP A CB  1 
ATOM   1017  C CG  . ASP A 1 127 ? -13.941 -11.073 -5.823  1.00 32.55  ? 127 ASP A CG  1 
ATOM   1018  O OD1 . ASP A 1 127 ? -13.853 -9.900  -6.211  1.00 34.87  ? 127 ASP A OD1 1 
ATOM   1019  O OD2 . ASP A 1 127 ? -14.862 -11.489 -5.038  1.00 30.88  ? 127 ASP A OD2 1 
ATOM   1020  N N   . VAL A 1 128 ? -11.470 -13.810 -8.519  1.00 24.31  ? 128 VAL A N   1 
ATOM   1021  C CA  . VAL A 1 128 ? -10.553 -14.868 -8.918  1.00 24.78  ? 128 VAL A CA  1 
ATOM   1022  C C   . VAL A 1 128 ? -9.454  -14.306 -9.809  1.00 26.14  ? 128 VAL A C   1 
ATOM   1023  O O   . VAL A 1 128 ? -8.269  -14.575 -9.571  1.00 25.94  ? 128 VAL A O   1 
ATOM   1024  C CB  . VAL A 1 128 ? -11.273 -16.069 -9.560  1.00 22.58  ? 128 VAL A CB  1 
ATOM   1025  C CG1 . VAL A 1 128 ? -10.309 -17.042 -10.192 1.00 26.56  ? 128 VAL A CG1 1 
ATOM   1026  C CG2 . VAL A 1 128 ? -12.100 -16.781 -8.518  1.00 22.56  ? 128 VAL A CG2 1 
ATOM   1027  N N   . LEU A 1 129 ? -9.823  -13.483 -10.796 1.00 26.98  ? 129 LEU A N   1 
ATOM   1028  C CA  . LEU A 1 129 ? -8.825  -12.935 -11.693 1.00 26.39  ? 129 LEU A CA  1 
ATOM   1029  C C   . LEU A 1 129 ? -7.839  -12.053 -10.919 1.00 26.71  ? 129 LEU A C   1 
ATOM   1030  O O   . LEU A 1 129 ? -6.650  -12.109 -11.199 1.00 30.35  ? 129 LEU A O   1 
ATOM   1031  C CB  . LEU A 1 129 ? -9.506  -12.147 -12.805 1.00 26.81  ? 129 LEU A CB  1 
ATOM   1032  C CG  . LEU A 1 129 ? -10.262 -12.989 -13.829 1.00 27.54  ? 129 LEU A CG  1 
ATOM   1033  C CD1 . LEU A 1 129 ? -11.168 -12.104 -14.636 1.00 27.15  ? 129 LEU A CD1 1 
ATOM   1034  C CD2 . LEU A 1 129 ? -9.309  -13.752 -14.738 1.00 28.79  ? 129 LEU A CD2 1 
ATOM   1035  N N   . ARG A 1 130 ? -8.307  -11.234 -9.962  1.00 24.81  ? 130 ARG A N   1 
ATOM   1036  C CA  . ARG A 1 130 ? -7.408  -10.332 -9.270  1.00 25.46  ? 130 ARG A CA  1 
ATOM   1037  C C   . ARG A 1 130 ? -6.518  -11.086 -8.292  1.00 25.50  ? 130 ARG A C   1 
ATOM   1038  O O   . ARG A 1 130 ? -5.431  -10.632 -7.997  1.00 28.07  ? 130 ARG A O   1 
ATOM   1039  C CB  . ARG A 1 130 ? -8.105  -9.197  -8.517  1.00 29.34  ? 130 ARG A CB  1 
ATOM   1040  C CG  . ARG A 1 130 ? -8.713  -8.124  -9.401  1.00 35.54  ? 130 ARG A CG  1 
ATOM   1041  C CD  . ARG A 1 130 ? -9.196  -6.906  -8.606  1.00 29.91  ? 130 ARG A CD  1 
ATOM   1042  N NE  . ARG A 1 130 ? -8.091  -6.028  -8.304  1.00 27.88  ? 130 ARG A NE  1 
ATOM   1043  C CZ  . ARG A 1 130 ? -7.491  -5.238  -9.189  1.00 28.56  ? 130 ARG A CZ  1 
ATOM   1044  N NH1 . ARG A 1 130 ? -6.567  -4.387  -8.772  1.00 27.90  ? 130 ARG A NH1 1 
ATOM   1045  N NH2 . ARG A 1 130 ? -7.844  -5.258  -10.472 1.00 24.89  ? 130 ARG A NH2 1 
ATOM   1046  N N   . ALA A 1 131 ? -6.926  -12.270 -7.838  1.00 27.49  ? 131 ALA A N   1 
ATOM   1047  C CA  . ALA A 1 131 ? -6.094  -13.036 -6.903  1.00 30.55  ? 131 ALA A CA  1 
ATOM   1048  C C   . ALA A 1 131 ? -4.906  -13.709 -7.598  1.00 28.73  ? 131 ALA A C   1 
ATOM   1049  O O   . ALA A 1 131 ? -3.948  -14.072 -6.928  1.00 27.86  ? 131 ALA A O   1 
ATOM   1050  C CB  . ALA A 1 131 ? -6.937  -14.090 -6.213  1.00 28.30  ? 131 ALA A CB  1 
ATOM   1051  N N   . MET A 1 132 ? -4.969  -13.876 -8.922  1.00 27.16  ? 132 MET A N   1 
ATOM   1052  C CA  . MET A 1 132 ? -3.860  -14.412 -9.695  1.00 31.01  ? 132 MET A CA  1 
ATOM   1053  C C   . MET A 1 132 ? -2.816  -13.312 -9.866  1.00 27.92  ? 132 MET A C   1 
ATOM   1054  O O   . MET A 1 132 ? -3.143  -12.165 -10.149 1.00 26.59  ? 132 MET A O   1 
ATOM   1055  C CB  . MET A 1 132 ? -4.317  -14.896 -11.074 1.00 29.93  ? 132 MET A CB  1 
ATOM   1056  C CG  . MET A 1 132 ? -5.394  -15.965 -10.966 1.00 34.21  ? 132 MET A CG  1 
ATOM   1057  S SD  . MET A 1 132 ? -5.961  -16.489 -12.604 1.00 35.35  ? 132 MET A SD  1 
ATOM   1058  C CE  . MET A 1 132 ? -4.843  -17.868 -12.740 1.00 36.53  ? 132 MET A CE  1 
ATOM   1059  N N   . PRO A 1 133 ? -1.519  -13.602 -9.667  1.00 26.67  ? 133 PRO A N   1 
ATOM   1060  C CA  . PRO A 1 133 ? -0.485  -12.596 -9.853  1.00 25.77  ? 133 PRO A CA  1 
ATOM   1061  C C   . PRO A 1 133 ? -0.534  -12.002 -11.252 1.00 27.44  ? 133 PRO A C   1 
ATOM   1062  O O   . PRO A 1 133 ? -0.786  -12.721 -12.209 1.00 27.17  ? 133 PRO A O   1 
ATOM   1063  C CB  . PRO A 1 133 ? 0.821   -13.385 -9.679  1.00 25.14  ? 133 PRO A CB  1 
ATOM   1064  C CG  . PRO A 1 133 ? 0.429   -14.569 -8.880  1.00 26.90  ? 133 PRO A CG  1 
ATOM   1065  C CD  . PRO A 1 133 ? -0.975  -14.916 -9.313  1.00 26.48  ? 133 PRO A CD  1 
ATOM   1066  N N   . VAL A 1 134 ? -0.383  -10.674 -11.363 1.00 26.13  ? 134 VAL A N   1 
ATOM   1067  C CA  . VAL A 1 134 ? -0.594  -10.007 -12.635 1.00 24.14  ? 134 VAL A CA  1 
ATOM   1068  C C   . VAL A 1 134 ? 0.359   -10.501 -13.724 1.00 23.25  ? 134 VAL A C   1 
ATOM   1069  O O   . VAL A 1 134 ? 0.059   -10.337 -14.922 1.00 25.29  ? 134 VAL A O   1 
ATOM   1070  C CB  . VAL A 1 134 ? -0.472  -8.481  -12.468 1.00 26.81  ? 134 VAL A CB  1 
ATOM   1071  C CG1 . VAL A 1 134 ? 0.981   -8.047  -12.228 1.00 25.24  ? 134 VAL A CG1 1 
ATOM   1072  C CG2 . VAL A 1 134 ? -1.084  -7.713  -13.635 1.00 28.24  ? 134 VAL A CG2 1 
ATOM   1073  N N   . ASP A 1 135 ? 1.497   -11.096 -13.356 1.00 24.91  ? 135 ASP A N   1 
ATOM   1074  C CA  . ASP A 1 135 ? 2.435   -11.606 -14.358 1.00 27.96  ? 135 ASP A CA  1 
ATOM   1075  C C   . ASP A 1 135 ? 2.074   -13.020 -14.824 1.00 26.16  ? 135 ASP A C   1 
ATOM   1076  O O   . ASP A 1 135 ? 2.815   -13.621 -15.576 1.00 28.23  ? 135 ASP A O   1 
ATOM   1077  C CB  . ASP A 1 135 ? 3.887   -11.591 -13.858 1.00 29.42  ? 135 ASP A CB  1 
ATOM   1078  C CG  . ASP A 1 135 ? 4.121   -12.446 -12.627 1.00 32.30  ? 135 ASP A CG  1 
ATOM   1079  O OD1 . ASP A 1 135 ? 3.169   -13.124 -12.185 1.00 31.09  ? 135 ASP A OD1 1 
ATOM   1080  O OD2 . ASP A 1 135 ? 5.248   -12.438 -12.111 1.00 30.67  ? 135 ASP A OD2 1 
ATOM   1081  N N   . THR A 1 136 ? 0.931   -13.556 -14.427 1.00 25.25  ? 136 THR A N   1 
ATOM   1082  C CA  . THR A 1 136 ? 0.479   -14.852 -14.921 1.00 25.44  ? 136 THR A CA  1 
ATOM   1083  C C   . THR A 1 136 ? 0.169   -14.770 -16.412 1.00 27.36  ? 136 THR A C   1 
ATOM   1084  O O   . THR A 1 136 ? -0.353  -13.762 -16.897 1.00 25.54  ? 136 THR A O   1 
ATOM   1085  C CB  . THR A 1 136 ? -0.746  -15.303 -14.115 1.00 27.00  ? 136 THR A CB  1 
ATOM   1086  O OG1 . THR A 1 136 ? -0.389  -15.479 -12.734 1.00 25.86  ? 136 THR A OG1 1 
ATOM   1087  C CG2 . THR A 1 136 ? -1.329  -16.596 -14.636 1.00 28.65  ? 136 THR A CG2 1 
ATOM   1088  N N   . HIS A 1 137 ? 0.519   -15.813 -17.167 1.00 25.24  ? 137 HIS A N   1 
ATOM   1089  C CA  . HIS A 1 137 ? 0.231   -15.819 -18.590 1.00 27.31  ? 137 HIS A CA  1 
ATOM   1090  C C   . HIS A 1 137 ? -1.246  -15.527 -18.819 1.00 22.67  ? 137 HIS A C   1 
ATOM   1091  O O   . HIS A 1 137 ? -2.136  -16.011 -18.103 1.00 22.91  ? 137 HIS A O   1 
ATOM   1092  C CB  . HIS A 1 137 ? 0.698   -17.133 -19.235 1.00 30.82  ? 137 HIS A CB  1 
ATOM   1093  C CG  . HIS A 1 137 ? 0.661   -17.102 -20.725 1.00 30.61  ? 137 HIS A CG  1 
ATOM   1094  N ND1 . HIS A 1 137 ? -0.520  -17.136 -21.432 1.00 29.20  ? 137 HIS A ND1 1 
ATOM   1095  C CD2 . HIS A 1 137 ? 1.647   -17.074 -21.643 1.00 29.07  ? 137 HIS A CD2 1 
ATOM   1096  C CE1 . HIS A 1 137 ? -0.248  -17.070 -22.732 1.00 30.27  ? 137 HIS A CE1 1 
ATOM   1097  N NE2 . HIS A 1 137 ? 1.056   -17.026 -22.883 1.00 29.46  ? 137 HIS A NE2 1 
ATOM   1098  N N   . PRO A 1 138 ? -1.595  -14.711 -19.811 1.00 22.92  ? 138 PRO A N   1 
ATOM   1099  C CA  . PRO A 1 138 ? -3.011  -14.355 -19.994 1.00 26.46  ? 138 PRO A CA  1 
ATOM   1100  C C   . PRO A 1 138 ? -3.943  -15.529 -20.311 1.00 24.92  ? 138 PRO A C   1 
ATOM   1101  O O   . PRO A 1 138 ? -5.117  -15.481 -19.971 1.00 23.18  ? 138 PRO A O   1 
ATOM   1102  C CB  . PRO A 1 138 ? -2.960  -13.269 -21.068 1.00 25.87  ? 138 PRO A CB  1 
ATOM   1103  C CG  . PRO A 1 138 ? -1.655  -13.487 -21.776 1.00 27.25  ? 138 PRO A CG  1 
ATOM   1104  C CD  . PRO A 1 138 ? -0.693  -14.010 -20.728 1.00 24.88  ? 138 PRO A CD  1 
ATOM   1105  N N   . MET A 1 139 ? -3.437  -16.604 -20.941 1.00 24.08  ? 139 MET A N   1 
ATOM   1106  C CA  . MET A 1 139 ? -4.277  -17.755 -21.248 1.00 23.83  ? 139 MET A CA  1 
ATOM   1107  C C   . MET A 1 139 ? -4.544  -18.573 -19.980 1.00 23.45  ? 139 MET A C   1 
ATOM   1108  O O   . MET A 1 139 ? -5.545  -19.246 -19.866 1.00 22.82  ? 139 MET A O   1 
ATOM   1109  C CB  . MET A 1 139 ? -3.626  -18.660 -22.296 1.00 23.91  ? 139 MET A CB  1 
ATOM   1110  C CG  . MET A 1 139 ? -3.782  -18.169 -23.733 1.00 25.62  ? 139 MET A CG  1 
ATOM   1111  S SD  . MET A 1 139 ? -5.510  -18.172 -24.250 1.00 28.14  ? 139 MET A SD  1 
ATOM   1112  C CE  . MET A 1 139 ? -5.848  -19.922 -24.357 1.00 27.53  ? 139 MET A CE  1 
ATOM   1113  N N   . THR A 1 140 ? -3.672  -18.501 -18.981 1.00 26.48  ? 140 THR A N   1 
ATOM   1114  C CA  . THR A 1 140 ? -3.960  -19.140 -17.704 1.00 24.81  ? 140 THR A CA  1 
ATOM   1115  C C   . THR A 1 140 ? -5.078  -18.393 -16.984 1.00 24.73  ? 140 THR A C   1 
ATOM   1116  O O   . THR A 1 140 ? -5.983  -19.010 -16.434 1.00 24.79  ? 140 THR A O   1 
ATOM   1117  C CB  . THR A 1 140 ? -2.719  -19.163 -16.820 1.00 23.68  ? 140 THR A CB  1 
ATOM   1118  O OG1 . THR A 1 140 ? -1.778  -19.879 -17.619 1.00 24.78  ? 140 THR A OG1 1 
ATOM   1119  C CG2 . THR A 1 140 ? -2.955  -19.787 -15.462 1.00 23.64  ? 140 THR A CG2 1 
ATOM   1120  N N   . MET A 1 141 ? -4.992  -17.059 -16.978 1.00 24.90  ? 141 MET A N   1 
ATOM   1121  C CA  . MET A 1 141 ? -6.018  -16.211 -16.388 1.00 24.48  ? 141 MET A CA  1 
ATOM   1122  C C   . MET A 1 141 ? -7.361  -16.447 -17.107 1.00 25.98  ? 141 MET A C   1 
ATOM   1123  O O   . MET A 1 141 ? -8.386  -16.553 -16.463 1.00 22.69  ? 141 MET A O   1 
ATOM   1124  C CB  . MET A 1 141 ? -5.626  -14.737 -16.528 1.00 25.06  ? 141 MET A CB  1 
ATOM   1125  C CG  . MET A 1 141 ? -4.461  -14.314 -15.641 1.00 24.82  ? 141 MET A CG  1 
ATOM   1126  S SD  . MET A 1 141 ? -4.233  -12.551 -15.944 1.00 28.54  ? 141 MET A SD  1 
ATOM   1127  C CE  . MET A 1 141 ? -2.820  -12.149 -14.921 1.00 30.43  ? 141 MET A CE  1 
ATOM   1128  N N   . PHE A 1 142 ? -7.361  -16.528 -18.438 1.00 22.98  ? 142 PHE A N   1 
ATOM   1129  C CA  . PHE A 1 142 ? -8.589  -16.695 -19.209 1.00 25.11  ? 142 PHE A CA  1 
ATOM   1130  C C   . PHE A 1 142 ? -9.293  -18.010 -18.843 1.00 23.49  ? 142 PHE A C   1 
ATOM   1131  O O   . PHE A 1 142 ? -10.497 -18.056 -18.519 1.00 24.87  ? 142 PHE A O   1 
ATOM   1132  C CB  . PHE A 1 142 ? -8.244  -16.552 -20.697 1.00 24.90  ? 142 PHE A CB  1 
ATOM   1133  C CG  . PHE A 1 142 ? -9.399  -16.553 -21.655 1.00 25.46  ? 142 PHE A CG  1 
ATOM   1134  C CD1 . PHE A 1 142 ? -10.403 -15.601 -21.568 1.00 26.27  ? 142 PHE A CD1 1 
ATOM   1135  C CD2 . PHE A 1 142 ? -9.390  -17.421 -22.738 1.00 26.93  ? 142 PHE A CD2 1 
ATOM   1136  C CE1 . PHE A 1 142 ? -11.422 -15.561 -22.508 1.00 29.12  ? 142 PHE A CE1 1 
ATOM   1137  C CE2 . PHE A 1 142 ? -10.413 -17.385 -23.677 1.00 29.76  ? 142 PHE A CE2 1 
ATOM   1138  C CZ  . PHE A 1 142 ? -11.429 -16.462 -23.558 1.00 29.31  ? 142 PHE A CZ  1 
ATOM   1139  N N   . ALA A 1 143 ? -8.510  -19.092 -18.845 1.00 24.30  ? 143 ALA A N   1 
ATOM   1140  C CA  . ALA A 1 143 ? -9.044  -20.396 -18.521 1.00 22.67  ? 143 ALA A CA  1 
ATOM   1141  C C   . ALA A 1 143 ? -9.585  -20.399 -17.097 1.00 23.41  ? 143 ALA A C   1 
ATOM   1142  O O   . ALA A 1 143 ? -10.620 -20.984 -16.856 1.00 26.34  ? 143 ALA A O   1 
ATOM   1143  C CB  . ALA A 1 143 ? -8.019  -21.456 -18.764 1.00 23.55  ? 143 ALA A CB  1 
ATOM   1144  N N   . ALA A 1 144 ? -8.898  -19.748 -16.164 1.00 22.47  ? 144 ALA A N   1 
ATOM   1145  C CA  . ALA A 1 144 ? -9.274  -19.804 -14.771 1.00 26.29  ? 144 ALA A CA  1 
ATOM   1146  C C   . ALA A 1 144 ? -10.566 -19.029 -14.546 1.00 25.09  ? 144 ALA A C   1 
ATOM   1147  O O   . ALA A 1 144 ? -11.392 -19.435 -13.737 1.00 26.43  ? 144 ALA A O   1 
ATOM   1148  C CB  . ALA A 1 144 ? -8.189  -19.260 -13.891 1.00 25.81  ? 144 ALA A CB  1 
ATOM   1149  N N   . GLY A 1 145 ? -10.715 -17.892 -15.212 1.00 25.77  ? 145 GLY A N   1 
ATOM   1150  C CA  . GLY A 1 145 ? -11.923 -17.106 -15.033 1.00 24.31  ? 145 GLY A CA  1 
ATOM   1151  C C   . GLY A 1 145 ? -13.145 -17.828 -15.584 1.00 22.49  ? 145 GLY A C   1 
ATOM   1152  O O   . GLY A 1 145 ? -14.222 -17.751 -15.012 1.00 23.46  ? 145 GLY A O   1 
ATOM   1153  N N   . ILE A 1 146 ? -12.980 -18.460 -16.740 1.00 24.87  ? 146 ILE A N   1 
ATOM   1154  C CA  . ILE A 1 146 ? -14.032 -19.267 -17.343 1.00 24.80  ? 146 ILE A CA  1 
ATOM   1155  C C   . ILE A 1 146 ? -14.391 -20.408 -16.402 1.00 25.91  ? 146 ILE A C   1 
ATOM   1156  O O   . ILE A 1 146 ? -15.572 -20.628 -16.113 1.00 25.73  ? 146 ILE A O   1 
ATOM   1157  C CB  . ILE A 1 146 ? -13.602 -19.824 -18.717 1.00 25.63  ? 146 ILE A CB  1 
ATOM   1158  C CG1 . ILE A 1 146 ? -13.362 -18.716 -19.736 1.00 25.59  ? 146 ILE A CG1 1 
ATOM   1159  C CG2 . ILE A 1 146 ? -14.632 -20.835 -19.213 1.00 26.36  ? 146 ILE A CG2 1 
ATOM   1160  C CD1 . ILE A 1 146 ? -12.628 -19.191 -20.963 1.00 26.75  ? 146 ILE A CD1 1 
ATOM   1161  N N   . LEU A 1 147 ? -13.372 -21.148 -15.925 1.00 24.32  ? 147 LEU A N   1 
ATOM   1162  C CA  . LEU A 1 147 ? -13.655 -22.242 -15.007 1.00 23.84  ? 147 LEU A CA  1 
ATOM   1163  C C   . LEU A 1 147 ? -14.379 -21.761 -13.740 1.00 24.93  ? 147 LEU A C   1 
ATOM   1164  O O   . LEU A 1 147 ? -15.271 -22.422 -13.250 1.00 26.71  ? 147 LEU A O   1 
ATOM   1165  C CB  . LEU A 1 147 ? -12.343 -22.939 -14.690 1.00 23.17  ? 147 LEU A CB  1 
ATOM   1166  C CG  . LEU A 1 147 ? -12.435 -24.094 -13.707 1.00 25.30  ? 147 LEU A CG  1 
ATOM   1167  C CD1 . LEU A 1 147 ? -13.401 -25.150 -14.203 1.00 24.90  ? 147 LEU A CD1 1 
ATOM   1168  C CD2 . LEU A 1 147 ? -11.063 -24.685 -13.473 1.00 25.88  ? 147 LEU A CD2 1 
ATOM   1169  N N   . ALA A 1 148 ? -14.018 -20.611 -13.161 1.00 26.14  ? 148 ALA A N   1 
ATOM   1170  C CA  . ALA A 1 148 ? -14.677 -20.176 -11.927 1.00 26.28  ? 148 ALA A CA  1 
ATOM   1171  C C   . ALA A 1 148 ? -16.187 -19.984 -12.103 1.00 26.46  ? 148 ALA A C   1 
ATOM   1172  O O   . ALA A 1 148 ? -16.988 -20.165 -11.180 1.00 25.54  ? 148 ALA A O   1 
ATOM   1173  C CB  . ALA A 1 148 ? -14.055 -18.896 -11.450 1.00 27.01  ? 148 ALA A CB  1 
ATOM   1174  N N   . MET A 1 149 ? -16.599 -19.656 -13.324 1.00 24.05  ? 149 MET A N   1 
ATOM   1175  C CA  . MET A 1 149 ? -17.976 -19.333 -13.584 1.00 25.82  ? 149 MET A CA  1 
ATOM   1176  C C   . MET A 1 149 ? -18.785 -20.615 -13.766 1.00 27.82  ? 149 MET A C   1 
ATOM   1177  O O   . MET A 1 149 ? -19.995 -20.564 -13.965 1.00 29.75  ? 149 MET A O   1 
ATOM   1178  C CB  . MET A 1 149 ? -18.007 -18.408 -14.804 1.00 28.74  ? 149 MET A CB  1 
ATOM   1179  C CG  . MET A 1 149 ? -19.339 -17.712 -15.050 1.00 31.84  ? 149 MET A CG  1 
ATOM   1180  S SD  . MET A 1 149 ? -19.101 -16.439 -16.350 1.00 31.86  ? 149 MET A SD  1 
ATOM   1181  C CE  . MET A 1 149 ? -20.841 -16.113 -16.642 1.00 32.39  ? 149 MET A CE  1 
ATOM   1182  N N   . GLN A 1 150 ? -18.149 -21.778 -13.551 1.00 27.48  ? 150 GLN A N   1 
ATOM   1183  C CA  . GLN A 1 150 ? -18.825 -23.060 -13.640 1.00 24.41  ? 150 GLN A CA  1 
ATOM   1184  C C   . GLN A 1 150 ? -19.889 -23.157 -12.555 1.00 25.73  ? 150 GLN A C   1 
ATOM   1185  O O   . GLN A 1 150 ? -20.866 -23.870 -12.719 1.00 26.31  ? 150 GLN A O   1 
ATOM   1186  C CB  . GLN A 1 150 ? -17.828 -24.208 -13.533 1.00 25.93  ? 150 GLN A CB  1 
ATOM   1187  C CG  . GLN A 1 150 ? -18.428 -25.613 -13.610 1.00 28.67  ? 150 GLN A CG  1 
ATOM   1188  C CD  . GLN A 1 150 ? -19.072 -26.166 -12.357 1.00 31.30  ? 150 GLN A CD  1 
ATOM   1189  O OE1 . GLN A 1 150 ? -18.763 -25.840 -11.206 1.00 27.98  ? 150 GLN A OE1 1 
ATOM   1190  N NE2 . GLN A 1 150 ? -20.024 -27.051 -12.589 1.00 27.49  ? 150 GLN A NE2 1 
ATOM   1191  N N   . ARG A 1 151 ? -19.739 -22.402 -11.462 1.00 25.59  ? 151 ARG A N   1 
ATOM   1192  C CA  . ARG A 1 151 ? -20.767 -22.380 -10.429 1.00 25.87  ? 151 ARG A CA  1 
ATOM   1193  C C   . ARG A 1 151 ? -22.143 -21.937 -10.962 1.00 28.59  ? 151 ARG A C   1 
ATOM   1194  O O   . ARG A 1 151 ? -23.147 -22.271 -10.361 1.00 26.73  ? 151 ARG A O   1 
ATOM   1195  C CB  . ARG A 1 151 ? -20.298 -21.443 -9.306  1.00 28.40  ? 151 ARG A CB  1 
ATOM   1196  C CG  . ARG A 1 151 ? -21.312 -21.254 -8.182  1.00 30.18  ? 151 ARG A CG  1 
ATOM   1197  C CD  . ARG A 1 151 ? -20.954 -20.033 -7.372  1.00 30.81  ? 151 ARG A CD  1 
ATOM   1198  N NE  . ARG A 1 151 ? -21.762 -19.868 -6.167  1.00 34.56  ? 151 ARG A NE  1 
ATOM   1199  C CZ  . ARG A 1 151 ? -22.804 -19.050 -6.070  1.00 38.56  ? 151 ARG A CZ  1 
ATOM   1200  N NH1 . ARG A 1 151 ? -23.217 -18.352 -7.123  1.00 33.45  ? 151 ARG A NH1 1 
ATOM   1201  N NH2 . ARG A 1 151 ? -23.474 -19.000 -4.934  1.00 39.31  ? 151 ARG A NH2 1 
ATOM   1202  N N   . GLU A 1 152 ? -22.202 -21.148 -12.050 1.00 28.34  ? 152 GLU A N   1 
ATOM   1203  C CA  . GLU A 1 152 ? -23.462 -20.674 -12.613 1.00 31.63  ? 152 GLU A CA  1 
ATOM   1204  C C   . GLU A 1 152 ? -24.008 -21.630 -13.688 1.00 33.04  ? 152 GLU A C   1 
ATOM   1205  O O   . GLU A 1 152 ? -24.922 -21.267 -14.417 1.00 29.49  ? 152 GLU A O   1 
ATOM   1206  C CB  . GLU A 1 152 ? -23.258 -19.289 -13.252 1.00 32.53  ? 152 GLU A CB  1 
ATOM   1207  C CG  . GLU A 1 152 ? -22.628 -18.244 -12.314 1.00 33.76  ? 152 GLU A CG  1 
ATOM   1208  C CD  . GLU A 1 152 ? -23.143 -18.251 -10.870 1.00 36.91  ? 152 GLU A CD  1 
ATOM   1209  O OE1 . GLU A 1 152 ? -22.325 -18.168 -9.935  1.00 36.63  ? 152 GLU A OE1 1 
ATOM   1210  O OE2 . GLU A 1 152 ? -24.363 -18.377 -10.667 1.00 40.33  ? 152 GLU A OE2 1 
ATOM   1211  N N   . SER A 1 153 ? -23.446 -22.841 -13.826 1.00 33.28  ? 153 SER A N   1 
ATOM   1212  C CA  . SER A 1 153 ? -23.850 -23.745 -14.899 1.00 32.39  ? 153 SER A CA  1 
ATOM   1213  C C   . SER A 1 153 ? -25.288 -24.242 -14.682 1.00 31.52  ? 153 SER A C   1 
ATOM   1214  O O   . SER A 1 153 ? -25.571 -24.875 -13.687 1.00 31.54  ? 153 SER A O   1 
ATOM   1215  C CB  . SER A 1 153 ? -22.929 -24.915 -15.036 1.00 30.90  ? 153 SER A CB  1 
ATOM   1216  O OG  . SER A 1 153 ? -23.419 -25.805 -16.040 1.00 28.69  ? 153 SER A OG  1 
ATOM   1217  N N   . VAL A 1 154 ? -26.154 -23.983 -15.663 1.00 30.55  ? 154 VAL A N   1 
ATOM   1218  C CA  . VAL A 1 154 ? -27.518 -24.481 -15.702 1.00 32.59  ? 154 VAL A CA  1 
ATOM   1219  C C   . VAL A 1 154 ? -27.532 -25.974 -16.033 1.00 33.12  ? 154 VAL A C   1 
ATOM   1220  O O   . VAL A 1 154 ? -28.285 -26.726 -15.428 1.00 33.15  ? 154 VAL A O   1 
ATOM   1221  C CB  . VAL A 1 154 ? -28.311 -23.636 -16.715 1.00 35.69  ? 154 VAL A CB  1 
ATOM   1222  C CG1 . VAL A 1 154 ? -29.648 -24.251 -17.103 1.00 41.88  ? 154 VAL A CG1 1 
ATOM   1223  C CG2 . VAL A 1 154 ? -28.489 -22.222 -16.173 1.00 38.30  ? 154 VAL A CG2 1 
ATOM   1224  N N   . PHE A 1 155 ? -26.640 -26.413 -16.926 1.00 33.92  ? 155 PHE A N   1 
ATOM   1225  C CA  . PHE A 1 155 ? -26.500 -27.831 -17.227 1.00 31.67  ? 155 PHE A CA  1 
ATOM   1226  C C   . PHE A 1 155 ? -26.150 -28.633 -15.985 1.00 34.01  ? 155 PHE A C   1 
ATOM   1227  O O   . PHE A 1 155 ? -26.807 -29.634 -15.706 1.00 31.28  ? 155 PHE A O   1 
ATOM   1228  C CB  . PHE A 1 155 ? -25.460 -28.082 -18.308 1.00 32.94  ? 155 PHE A CB  1 
ATOM   1229  C CG  . PHE A 1 155 ? -25.429 -29.500 -18.794 1.00 34.40  ? 155 PHE A CG  1 
ATOM   1230  C CD1 . PHE A 1 155 ? -24.758 -30.477 -18.082 1.00 40.59  ? 155 PHE A CD1 1 
ATOM   1231  C CD2 . PHE A 1 155 ? -26.134 -29.868 -19.931 1.00 35.29  ? 155 PHE A CD2 1 
ATOM   1232  C CE1 . PHE A 1 155 ? -24.757 -31.787 -18.529 1.00 41.56  ? 155 PHE A CE1 1 
ATOM   1233  C CE2 . PHE A 1 155 ? -26.128 -31.178 -20.378 1.00 37.49  ? 155 PHE A CE2 1 
ATOM   1234  C CZ  . PHE A 1 155 ? -25.443 -32.132 -19.676 1.00 36.93  ? 155 PHE A CZ  1 
ATOM   1235  N N   . ALA A 1 156 ? -25.108 -28.211 -15.245 1.00 29.95  ? 156 ALA A N   1 
ATOM   1236  C CA  . ALA A 1 156 ? -24.717 -28.906 -14.025 1.00 30.78  ? 156 ALA A CA  1 
ATOM   1237  C C   . ALA A 1 156 ? -25.897 -29.013 -13.068 1.00 31.04  ? 156 ALA A C   1 
ATOM   1238  O O   . ALA A 1 156 ? -26.111 -30.061 -12.454 1.00 31.89  ? 156 ALA A O   1 
ATOM   1239  C CB  . ALA A 1 156 ? -23.560 -28.217 -13.312 1.00 36.81  ? 156 ALA A CB  1 
ATOM   1240  N N   . LYS A 1 157 ? -26.577 -27.894 -12.869 1.00 35.58  ? 157 LYS A N   1 
ATOM   1241  C CA  . LYS A 1 157 ? -27.635 -27.819 -11.881 1.00 39.45  ? 157 LYS A CA  1 
ATOM   1242  C C   . LYS A 1 157 ? -28.816 -28.708 -12.296 1.00 42.25  ? 157 LYS A C   1 
ATOM   1243  O O   . LYS A 1 157 ? -29.329 -29.469 -11.479 1.00 35.59  ? 157 LYS A O   1 
ATOM   1244  C CB  . LYS A 1 157 ? -28.045 -26.357 -11.703 1.00 41.30  ? 157 LYS A CB  1 
ATOM   1245  C CG  . LYS A 1 157 ? -29.301 -26.163 -10.874 1.00 53.07  ? 157 LYS A CG  1 
ATOM   1246  C CD  . LYS A 1 157 ? -29.313 -24.875 -10.100 1.00 61.03  ? 157 LYS A CD  1 
ATOM   1247  C CE  . LYS A 1 157 ? -30.410 -24.831 -9.059  1.00 66.08  ? 157 LYS A CE  1 
ATOM   1248  N NZ  . LYS A 1 157 ? -29.840 -24.563 -7.717  1.00 72.43  ? 157 LYS A NZ  1 
ATOM   1249  N N   . ARG A 1 158 ? -29.256 -28.590 -13.557 1.00 38.20  ? 158 ARG A N   1 
ATOM   1250  C CA  . ARG A 1 158 ? -30.386 -29.369 -14.044 1.00 38.98  ? 158 ARG A CA  1 
ATOM   1251  C C   . ARG A 1 158 ? -30.041 -30.857 -14.087 1.00 37.57  ? 158 ARG A C   1 
ATOM   1252  O O   . ARG A 1 158 ? -30.900 -31.702 -13.843 1.00 38.60  ? 158 ARG A O   1 
ATOM   1253  C CB  . ARG A 1 158 ? -30.885 -28.829 -15.387 1.00 39.23  ? 158 ARG A CB  1 
ATOM   1254  C CG  . ARG A 1 158 ? -32.018 -27.829 -15.213 1.00 46.89  ? 158 ARG A CG  1 
ATOM   1255  C CD  . ARG A 1 158 ? -31.919 -26.568 -16.037 1.00 58.68  ? 158 ARG A CD  1 
ATOM   1256  N NE  . ARG A 1 158 ? -32.381 -26.584 -17.423 1.00 70.59  ? 158 ARG A NE  1 
ATOM   1257  C CZ  . ARG A 1 158 ? -32.744 -25.490 -18.095 1.00 63.23  ? 158 ARG A CZ  1 
ATOM   1258  N NH1 . ARG A 1 158 ? -32.745 -25.496 -19.415 1.00 60.69  ? 158 ARG A NH1 1 
ATOM   1259  N NH2 . ARG A 1 158 ? -33.002 -24.364 -17.444 1.00 58.37  ? 158 ARG A NH2 1 
ATOM   1260  N N   . TYR A 1 159 ? -28.805 -31.197 -14.420 1.00 34.32  ? 159 TYR A N   1 
ATOM   1261  C CA  . TYR A 1 159 ? -28.413 -32.594 -14.417 1.00 41.49  ? 159 TYR A CA  1 
ATOM   1262  C C   . TYR A 1 159 ? -28.532 -33.220 -13.023 1.00 47.24  ? 159 TYR A C   1 
ATOM   1263  O O   . TYR A 1 159 ? -28.936 -34.381 -12.905 1.00 44.50  ? 159 TYR A O   1 
ATOM   1264  C CB  . TYR A 1 159 ? -26.978 -32.777 -14.889 1.00 41.49  ? 159 TYR A CB  1 
ATOM   1265  C CG  . TYR A 1 159 ? -26.641 -34.225 -15.074 1.00 42.77  ? 159 TYR A CG  1 
ATOM   1266  C CD1 . TYR A 1 159 ? -26.919 -34.862 -16.271 1.00 45.56  ? 159 TYR A CD1 1 
ATOM   1267  C CD2 . TYR A 1 159 ? -26.153 -34.974 -14.023 1.00 43.20  ? 159 TYR A CD2 1 
ATOM   1268  C CE1 . TYR A 1 159 ? -26.658 -36.210 -16.438 1.00 51.33  ? 159 TYR A CE1 1 
ATOM   1269  C CE2 . TYR A 1 159 ? -25.894 -36.320 -14.175 1.00 46.37  ? 159 TYR A CE2 1 
ATOM   1270  C CZ  . TYR A 1 159 ? -26.147 -36.936 -15.384 1.00 46.23  ? 159 TYR A CZ  1 
ATOM   1271  O OH  . TYR A 1 159 ? -25.866 -38.257 -15.548 1.00 53.70  ? 159 TYR A OH  1 
ATOM   1272  N N   . GLU A 1 160 ? -28.093 -32.485 -11.992 1.00 47.50  ? 160 GLU A N   1 
ATOM   1273  C CA  . GLU A 1 160 ? -28.197 -32.908 -10.597 1.00 58.69  ? 160 GLU A CA  1 
ATOM   1274  C C   . GLU A 1 160 ? -29.650 -33.118 -10.178 1.00 51.59  ? 160 GLU A C   1 
ATOM   1275  O O   . GLU A 1 160 ? -29.949 -34.016 -9.414  1.00 51.67  ? 160 GLU A O   1 
ATOM   1276  C CB  . GLU A 1 160 ? -27.625 -31.857 -9.636  1.00 66.28  ? 160 GLU A CB  1 
ATOM   1277  C CG  . GLU A 1 160 ? -26.110 -31.829 -9.567  1.00 76.14  ? 160 GLU A CG  1 
ATOM   1278  C CD  . GLU A 1 160 ? -25.510 -32.668 -8.454  1.00 91.30  ? 160 GLU A CD  1 
ATOM   1279  O OE1 . GLU A 1 160 ? -25.899 -33.849 -8.337  1.00 89.46  ? 160 GLU A OE1 1 
ATOM   1280  O OE2 . GLU A 1 160 ? -24.647 -32.139 -7.712  1.00 99.83  ? 160 GLU A OE2 1 
ATOM   1281  N N   . GLU A 1 161 ? -30.545 -32.245 -10.630 1.00 52.85  ? 161 GLU A N   1 
ATOM   1282  C CA  . GLU A 1 161 ? -31.935 -32.311 -10.219 1.00 57.49  ? 161 GLU A CA  1 
ATOM   1283  C C   . GLU A 1 161 ? -32.642 -33.465 -10.912 1.00 55.10  ? 161 GLU A C   1 
ATOM   1284  O O   . GLU A 1 161 ? -33.693 -33.872 -10.456 1.00 53.26  ? 161 GLU A O   1 
ATOM   1285  C CB  . GLU A 1 161 ? -32.663 -31.004 -10.542 1.00 65.10  ? 161 GLU A CB  1 
ATOM   1286  C CG  . GLU A 1 161 ? -32.160 -29.838 -9.707  1.00 69.66  ? 161 GLU A CG  1 
ATOM   1287  C CD  . GLU A 1 161 ? -32.590 -28.442 -10.127 1.00 66.74  ? 161 GLU A CD  1 
ATOM   1288  O OE1 . GLU A 1 161 ? -32.333 -27.512 -9.331  1.00 71.21  ? 161 GLU A OE1 1 
ATOM   1289  O OE2 . GLU A 1 161 ? -33.143 -28.277 -11.250 1.00 59.91  ? 161 GLU A OE2 1 
ATOM   1290  N N   . GLY A 1 162 ? -32.086 -33.961 -12.022 1.00 54.68  ? 162 GLY A N   1 
ATOM   1291  C CA  . GLY A 1 162 ? -32.778 -34.929 -12.858 1.00 49.50  ? 162 GLY A CA  1 
ATOM   1292  C C   . GLY A 1 162 ? -33.464 -34.206 -14.012 1.00 54.46  ? 162 GLY A C   1 
ATOM   1293  O O   . GLY A 1 162 ? -34.409 -33.456 -13.795 1.00 62.74  ? 162 GLY A O   1 
ATOM   1294  N N   . MET A 1 163 ? -32.890 -34.318 -15.211 1.00 50.23  ? 163 MET A N   1 
ATOM   1295  C CA  . MET A 1 163 ? -33.525 -33.801 -16.410 1.00 49.89  ? 163 MET A CA  1 
ATOM   1296  C C   . MET A 1 163 ? -33.479 -34.911 -17.443 1.00 46.38  ? 163 MET A C   1 
ATOM   1297  O O   . MET A 1 163 ? -32.645 -35.794 -17.357 1.00 49.07  ? 163 MET A O   1 
ATOM   1298  C CB  . MET A 1 163 ? -32.878 -32.530 -16.975 1.00 46.96  ? 163 MET A CB  1 
ATOM   1299  C CG  . MET A 1 163 ? -31.507 -32.682 -17.639 1.00 42.95  ? 163 MET A CG  1 
ATOM   1300  S SD  . MET A 1 163 ? -30.918 -31.103 -18.439 1.00 47.43  ? 163 MET A SD  1 
ATOM   1301  C CE  . MET A 1 163 ? -29.159 -31.245 -18.138 1.00 40.31  ? 163 MET A CE  1 
ATOM   1302  N N   . ARG A 1 164 ? -34.411 -34.890 -18.389 1.00 55.78  ? 164 ARG A N   1 
ATOM   1303  C CA  . ARG A 1 164 ? -34.398 -35.896 -19.438 1.00 63.40  ? 164 ARG A CA  1 
ATOM   1304  C C   . ARG A 1 164 ? -33.247 -35.563 -20.383 1.00 59.26  ? 164 ARG A C   1 
ATOM   1305  O O   . ARG A 1 164 ? -32.864 -34.394 -20.481 1.00 50.22  ? 164 ARG A O   1 
ATOM   1306  C CB  . ARG A 1 164 ? -35.771 -35.909 -20.109 1.00 71.37  ? 164 ARG A CB  1 
ATOM   1307  C CG  . ARG A 1 164 ? -36.897 -36.376 -19.195 1.00 81.50  ? 164 ARG A CG  1 
ATOM   1308  C CD  . ARG A 1 164 ? -38.255 -35.935 -19.710 1.00 87.80  ? 164 ARG A CD  1 
ATOM   1309  N NE  . ARG A 1 164 ? -38.339 -36.163 -21.147 1.00 97.83  ? 164 ARG A NE  1 
ATOM   1310  C CZ  . ARG A 1 164 ? -38.191 -35.225 -22.078 1.00 96.67  ? 164 ARG A CZ  1 
ATOM   1311  N NH1 . ARG A 1 164 ? -38.085 -33.956 -21.730 1.00 106.38 ? 164 ARG A NH1 1 
ATOM   1312  N NH2 . ARG A 1 164 ? -38.152 -35.561 -23.356 1.00 95.61  ? 164 ARG A NH2 1 
ATOM   1313  N N   . ARG A 1 165 ? -32.725 -36.584 -21.083 1.00 54.11  ? 165 ARG A N   1 
ATOM   1314  C CA  . ARG A 1 165 ? -31.572 -36.433 -21.960 1.00 52.27  ? 165 ARG A CA  1 
ATOM   1315  C C   . ARG A 1 165 ? -31.891 -35.477 -23.115 1.00 52.51  ? 165 ARG A C   1 
ATOM   1316  O O   . ARG A 1 165 ? -30.978 -34.909 -23.726 1.00 53.94  ? 165 ARG A O   1 
ATOM   1317  C CB  . ARG A 1 165 ? -31.133 -37.773 -22.558 1.00 57.86  ? 165 ARG A CB  1 
ATOM   1318  C CG  . ARG A 1 165 ? -31.127 -38.951 -21.591 1.00 71.62  ? 165 ARG A CG  1 
ATOM   1319  C CD  . ARG A 1 165 ? -30.841 -40.274 -22.283 1.00 75.35  ? 165 ARG A CD  1 
ATOM   1320  N NE  . ARG A 1 165 ? -29.498 -40.275 -22.860 1.00 80.31  ? 165 ARG A NE  1 
ATOM   1321  C CZ  . ARG A 1 165 ? -29.142 -40.888 -23.987 1.00 80.59  ? 165 ARG A CZ  1 
ATOM   1322  N NH1 . ARG A 1 165 ? -29.989 -41.682 -24.619 1.00 83.01  ? 165 ARG A NH1 1 
ATOM   1323  N NH2 . ARG A 1 165 ? -27.917 -40.733 -24.461 1.00 72.92  ? 165 ARG A NH2 1 
ATOM   1324  N N   . GLU A 1 166 ? -33.187 -35.319 -23.410 1.00 51.57  ? 166 GLU A N   1 
ATOM   1325  C CA  . GLU A 1 166 ? -33.698 -34.481 -24.479 1.00 50.10  ? 166 GLU A CA  1 
ATOM   1326  C C   . GLU A 1 166 ? -33.658 -33.002 -24.098 1.00 47.01  ? 166 GLU A C   1 
ATOM   1327  O O   . GLU A 1 166 ? -33.769 -32.148 -24.970 1.00 52.09  ? 166 GLU A O   1 
ATOM   1328  C CB  . GLU A 1 166 ? -35.150 -34.873 -24.788 1.00 64.33  ? 166 GLU A CB  1 
ATOM   1329  C CG  . GLU A 1 166 ? -35.309 -36.222 -25.493 1.00 72.48  ? 166 GLU A CG  1 
ATOM   1330  C CD  . GLU A 1 166 ? -35.150 -37.493 -24.664 1.00 76.70  ? 166 GLU A CD  1 
ATOM   1331  O OE1 . GLU A 1 166 ? -34.867 -38.550 -25.268 1.00 67.21  ? 166 GLU A OE1 1 
ATOM   1332  O OE2 . GLU A 1 166 ? -35.312 -37.437 -23.421 1.00 83.07  ? 166 GLU A OE2 1 
ATOM   1333  N N   . GLU A 1 167 ? -33.562 -32.686 -22.803 1.00 46.45  ? 167 GLU A N   1 
ATOM   1334  C CA  . GLU A 1 167 ? -33.423 -31.300 -22.383 1.00 50.66  ? 167 GLU A CA  1 
ATOM   1335  C C   . GLU A 1 167 ? -31.949 -30.857 -22.380 1.00 41.98  ? 167 GLU A C   1 
ATOM   1336  O O   . GLU A 1 167 ? -31.660 -29.692 -22.126 1.00 42.16  ? 167 GLU A O   1 
ATOM   1337  C CB  . GLU A 1 167 ? -33.935 -31.077 -20.961 1.00 58.09  ? 167 GLU A CB  1 
ATOM   1338  C CG  . GLU A 1 167 ? -35.318 -31.609 -20.637 1.00 66.17  ? 167 GLU A CG  1 
ATOM   1339  C CD  . GLU A 1 167 ? -35.585 -31.521 -19.134 1.00 74.45  ? 167 GLU A CD  1 
ATOM   1340  O OE1 . GLU A 1 167 ? -35.314 -30.423 -18.542 1.00 79.77  ? 167 GLU A OE1 1 
ATOM   1341  O OE2 . GLU A 1 167 ? -36.003 -32.553 -18.534 1.00 51.70  ? 167 GLU A OE2 1 
ATOM   1342  N N   . HIS A 1 168 ? -31.014 -31.786 -22.591 1.00 40.22  ? 168 HIS A N   1 
ATOM   1343  C CA  . HIS A 1 168 ? -29.597 -31.457 -22.564 1.00 39.72  ? 168 HIS A CA  1 
ATOM   1344  C C   . HIS A 1 168 ? -29.287 -30.248 -23.428 1.00 37.20  ? 168 HIS A C   1 
ATOM   1345  O O   . HIS A 1 168 ? -28.629 -29.335 -22.955 1.00 34.34  ? 168 HIS A O   1 
ATOM   1346  C CB  . HIS A 1 168 ? -28.724 -32.645 -22.957 1.00 37.80  ? 168 HIS A CB  1 
ATOM   1347  C CG  . HIS A 1 168 ? -28.653 -33.654 -21.863 1.00 36.40  ? 168 HIS A CG  1 
ATOM   1348  N ND1 . HIS A 1 168 ? -27.767 -34.711 -21.884 1.00 41.17  ? 168 HIS A ND1 1 
ATOM   1349  C CD2 . HIS A 1 168 ? -29.306 -33.731 -20.698 1.00 39.13  ? 168 HIS A CD2 1 
ATOM   1350  C CE1 . HIS A 1 168 ? -27.929 -35.420 -20.776 1.00 39.38  ? 168 HIS A CE1 1 
ATOM   1351  N NE2 . HIS A 1 168 ? -28.817 -34.820 -20.023 1.00 36.50  ? 168 HIS A NE2 1 
ATOM   1352  N N   . TRP A 1 169 ? -29.753 -30.239 -24.679 1.00 36.95  ? 169 TRP A N   1 
ATOM   1353  C CA  . TRP A 1 169 ? -29.252 -29.276 -25.640 1.00 37.01  ? 169 TRP A CA  1 
ATOM   1354  C C   . TRP A 1 169 ? -29.663 -27.871 -25.209 1.00 39.94  ? 169 TRP A C   1 
ATOM   1355  O O   . TRP A 1 169 ? -28.932 -26.917 -25.482 1.00 34.21  ? 169 TRP A O   1 
ATOM   1356  C CB  . TRP A 1 169 ? -29.664 -29.624 -27.078 1.00 38.71  ? 169 TRP A CB  1 
ATOM   1357  C CG  . TRP A 1 169 ? -31.121 -29.425 -27.344 1.00 38.10  ? 169 TRP A CG  1 
ATOM   1358  C CD1 . TRP A 1 169 ? -32.087 -30.384 -27.298 1.00 41.41  ? 169 TRP A CD1 1 
ATOM   1359  C CD2 . TRP A 1 169 ? -31.785 -28.189 -27.648 1.00 38.05  ? 169 TRP A CD2 1 
ATOM   1360  N NE1 . TRP A 1 169 ? -33.312 -29.833 -27.541 1.00 40.82  ? 169 TRP A NE1 1 
ATOM   1361  C CE2 . TRP A 1 169 ? -33.160 -28.498 -27.807 1.00 40.89  ? 169 TRP A CE2 1 
ATOM   1362  C CE3 . TRP A 1 169 ? -31.355 -26.880 -27.901 1.00 35.18  ? 169 TRP A CE3 1 
ATOM   1363  C CZ2 . TRP A 1 169 ? -34.110 -27.533 -28.144 1.00 35.72  ? 169 TRP A CZ2 1 
ATOM   1364  C CZ3 . TRP A 1 169 ? -32.295 -25.929 -28.243 1.00 36.66  ? 169 TRP A CZ3 1 
ATOM   1365  C CH2 . TRP A 1 169 ? -33.654 -26.253 -28.371 1.00 40.38  ? 169 TRP A CH2 1 
ATOM   1366  N N   . GLU A 1 170 ? -30.769 -27.786 -24.444 1.00 34.81  ? 170 GLU A N   1 
ATOM   1367  C CA  . GLU A 1 170 ? -31.365 -26.530 -24.038 1.00 36.50  ? 170 GLU A CA  1 
ATOM   1368  C C   . GLU A 1 170 ? -30.528 -25.915 -22.914 1.00 31.72  ? 170 GLU A C   1 
ATOM   1369  O O   . GLU A 1 170 ? -30.365 -24.713 -22.869 1.00 32.30  ? 170 GLU A O   1 
ATOM   1370  C CB  . GLU A 1 170 ? -32.817 -26.765 -23.604 1.00 43.41  ? 170 GLU A CB  1 
ATOM   1371  C CG  . GLU A 1 170 ? -33.671 -27.315 -24.748 1.00 52.88  ? 170 GLU A CG  1 
ATOM   1372  C CD  . GLU A 1 170 ? -35.164 -27.493 -24.524 1.00 61.73  ? 170 GLU A CD  1 
ATOM   1373  O OE1 . GLU A 1 170 ? -35.691 -28.551 -24.924 1.00 62.49  ? 170 GLU A OE1 1 
ATOM   1374  O OE2 . GLU A 1 170 ? -35.802 -26.575 -23.983 1.00 67.00  ? 170 GLU A OE2 1 
ATOM   1375  N N   . ALA A 1 171 ? -30.056 -26.741 -21.987 1.00 29.80  ? 171 ALA A N   1 
ATOM   1376  C CA  . ALA A 1 171 ? -29.212 -26.278 -20.900 1.00 32.53  ? 171 ALA A CA  1 
ATOM   1377  C C   . ALA A 1 171 ? -27.841 -25.888 -21.449 1.00 30.48  ? 171 ALA A C   1 
ATOM   1378  O O   . ALA A 1 171 ? -27.266 -24.896 -21.021 1.00 33.39  ? 171 ALA A O   1 
ATOM   1379  C CB  . ALA A 1 171 ? -29.157 -27.349 -19.853 1.00 34.73  ? 171 ALA A CB  1 
ATOM   1380  N N   . MET A 1 172 ? -27.355 -26.623 -22.458 1.00 33.12  ? 172 MET A N   1 
ATOM   1381  C CA  . MET A 1 172 ? -26.116 -26.295 -23.125 1.00 31.09  ? 172 MET A CA  1 
ATOM   1382  C C   . MET A 1 172 ? -26.225 -24.950 -23.841 1.00 31.70  ? 172 MET A C   1 
ATOM   1383  O O   . MET A 1 172 ? -25.281 -24.156 -23.876 1.00 25.90  ? 172 MET A O   1 
ATOM   1384  C CB  . MET A 1 172 ? -25.738 -27.366 -24.151 1.00 32.01  ? 172 MET A CB  1 
ATOM   1385  C CG  . MET A 1 172 ? -25.265 -28.665 -23.533 1.00 32.43  ? 172 MET A CG  1 
ATOM   1386  S SD  . MET A 1 172 ? -23.725 -28.654 -22.566 1.00 36.37  ? 172 MET A SD  1 
ATOM   1387  C CE  . MET A 1 172 ? -22.640 -27.805 -23.699 1.00 37.39  ? 172 MET A CE  1 
ATOM   1388  N N   . LEU A 1 173 ? -27.389 -24.660 -24.410 1.00 32.39  ? 173 LEU A N   1 
ATOM   1389  C CA  . LEU A 1 173 ? -27.549 -23.416 -25.152 1.00 34.41  ? 173 LEU A CA  1 
ATOM   1390  C C   . LEU A 1 173 ? -27.557 -22.210 -24.202 1.00 32.52  ? 173 LEU A C   1 
ATOM   1391  O O   . LEU A 1 173 ? -26.932 -21.183 -24.479 1.00 32.22  ? 173 LEU A O   1 
ATOM   1392  C CB  . LEU A 1 173 ? -28.831 -23.490 -25.984 1.00 36.17  ? 173 LEU A CB  1 
ATOM   1393  C CG  . LEU A 1 173 ? -29.280 -22.187 -26.638 1.00 36.23  ? 173 LEU A CG  1 
ATOM   1394  C CD1 . LEU A 1 173 ? -28.222 -21.641 -27.570 1.00 37.28  ? 173 LEU A CD1 1 
ATOM   1395  C CD2 . LEU A 1 173 ? -30.577 -22.402 -27.407 1.00 38.50  ? 173 LEU A CD2 1 
ATOM   1396  N N   . GLU A 1 174 ? -28.274 -22.335 -23.095 1.00 28.66  ? 174 GLU A N   1 
ATOM   1397  C CA  . GLU A 1 174 ? -28.368 -21.278 -22.093 1.00 32.18  ? 174 GLU A CA  1 
ATOM   1398  C C   . GLU A 1 174 ? -26.971 -20.972 -21.527 1.00 32.81  ? 174 GLU A C   1 
ATOM   1399  O O   . GLU A 1 174 ? -26.581 -19.810 -21.398 1.00 33.68  ? 174 GLU A O   1 
ATOM   1400  C CB  . GLU A 1 174 ? -29.285 -21.771 -20.973 1.00 34.61  ? 174 GLU A CB  1 
ATOM   1401  C CG  . GLU A 1 174 ? -29.723 -20.720 -20.000 1.00 43.90  ? 174 GLU A CG  1 
ATOM   1402  C CD  . GLU A 1 174 ? -30.535 -19.581 -20.594 1.00 46.40  ? 174 GLU A CD  1 
ATOM   1403  O OE1 . GLU A 1 174 ? -30.986 -19.692 -21.755 1.00 55.19  ? 174 GLU A OE1 1 
ATOM   1404  O OE2 . GLU A 1 174 ? -30.693 -18.575 -19.889 1.00 59.23  ? 174 GLU A OE2 1 
ATOM   1405  N N   . ASP A 1 175 ? -26.222 -22.039 -21.219 1.00 33.01  ? 175 ASP A N   1 
ATOM   1406  C CA  . ASP A 1 175 ? -24.877 -21.931 -20.685 1.00 30.25  ? 175 ASP A CA  1 
ATOM   1407  C C   . ASP A 1 175 ? -23.983 -21.270 -21.712 1.00 28.89  ? 175 ASP A C   1 
ATOM   1408  O O   . ASP A 1 175 ? -23.185 -20.414 -21.351 1.00 28.80  ? 175 ASP A O   1 
ATOM   1409  C CB  . ASP A 1 175 ? -24.338 -23.286 -20.220 1.00 30.10  ? 175 ASP A CB  1 
ATOM   1410  C CG  . ASP A 1 175 ? -24.729 -23.695 -18.805 1.00 30.19  ? 175 ASP A CG  1 
ATOM   1411  O OD1 . ASP A 1 175 ? -25.186 -22.813 -18.024 1.00 36.42  ? 175 ASP A OD1 1 
ATOM   1412  O OD2 . ASP A 1 175 ? -24.495 -24.891 -18.437 1.00 31.30  ? 175 ASP A OD2 1 
ATOM   1413  N N   . SER A 1 176 ? -24.164 -21.627 -22.988 1.00 29.43  ? 176 SER A N   1 
ATOM   1414  C CA  . SER A 1 176 ? -23.317 -21.123 -24.052 1.00 27.79  ? 176 SER A CA  1 
ATOM   1415  C C   . SER A 1 176 ? -23.540 -19.624 -24.232 1.00 28.89  ? 176 SER A C   1 
ATOM   1416  O O   . SER A 1 176 ? -22.571 -18.888 -24.448 1.00 31.88  ? 176 SER A O   1 
ATOM   1417  C CB  . SER A 1 176 ? -23.519 -21.898 -25.345 1.00 29.57  ? 176 SER A CB  1 
ATOM   1418  O OG  . SER A 1 176 ? -23.013 -23.243 -25.212 1.00 28.30  ? 176 SER A OG  1 
ATOM   1419  N N   . LEU A 1 177 ? -24.810 -19.184 -24.152 1.00 27.22  ? 177 LEU A N   1 
ATOM   1420  C CA  . LEU A 1 177 ? -25.140 -17.769 -24.274 1.00 28.31  ? 177 LEU A CA  1 
ATOM   1421  C C   . LEU A 1 177 ? -24.473 -16.987 -23.150 1.00 23.90  ? 177 LEU A C   1 
ATOM   1422  O O   . LEU A 1 177 ? -23.947 -15.933 -23.417 1.00 28.46  ? 177 LEU A O   1 
ATOM   1423  C CB  . LEU A 1 177 ? -26.660 -17.578 -24.225 1.00 28.81  ? 177 LEU A CB  1 
ATOM   1424  C CG  . LEU A 1 177 ? -27.392 -18.066 -25.475 1.00 31.75  ? 177 LEU A CG  1 
ATOM   1425  C CD1 . LEU A 1 177 ? -28.891 -18.129 -25.261 1.00 35.41  ? 177 LEU A CD1 1 
ATOM   1426  C CD2 . LEU A 1 177 ? -27.046 -17.167 -26.641 1.00 32.53  ? 177 LEU A CD2 1 
ATOM   1427  N N   . ASN A 1 178 ? -24.598 -17.472 -21.915 1.00 27.06  ? 178 ASN A N   1 
ATOM   1428  C CA  . ASN A 1 178 ? -23.960 -16.851 -20.765 1.00 28.87  ? 178 ASN A CA  1 
ATOM   1429  C C   . ASN A 1 178 ? -22.444 -16.795 -20.922 1.00 29.45  ? 178 ASN A C   1 
ATOM   1430  O O   . ASN A 1 178 ? -21.820 -15.758 -20.673 1.00 28.56  ? 178 ASN A O   1 
ATOM   1431  C CB  . ASN A 1 178 ? -24.356 -17.560 -19.478 1.00 26.14  ? 178 ASN A CB  1 
ATOM   1432  C CG  . ASN A 1 178 ? -25.802 -17.316 -19.096 1.00 33.04  ? 178 ASN A CG  1 
ATOM   1433  O OD1 . ASN A 1 178 ? -26.392 -16.322 -19.502 1.00 34.37  ? 178 ASN A OD1 1 
ATOM   1434  N ND2 . ASN A 1 178 ? -26.366 -18.194 -18.291 1.00 33.50  ? 178 ASN A ND2 1 
ATOM   1435  N N   . MET A 1 179 ? -21.844 -17.920 -21.318 1.00 26.88  ? 179 MET A N   1 
ATOM   1436  C CA  . MET A 1 179 ? -20.399 -17.988 -21.328 1.00 26.05  ? 179 MET A CA  1 
ATOM   1437  C C   . MET A 1 179 ? -19.870 -17.100 -22.441 1.00 27.66  ? 179 MET A C   1 
ATOM   1438  O O   . MET A 1 179 ? -18.908 -16.347 -22.242 1.00 27.49  ? 179 MET A O   1 
ATOM   1439  C CB  . MET A 1 179 ? -19.861 -19.400 -21.531 1.00 28.70  ? 179 MET A CB  1 
ATOM   1440  C CG  . MET A 1 179 ? -18.341 -19.416 -21.496 1.00 28.02  ? 179 MET A CG  1 
ATOM   1441  S SD  . MET A 1 179 ? -17.698 -21.018 -21.866 1.00 31.71  ? 179 MET A SD  1 
ATOM   1442  C CE  . MET A 1 179 ? -17.866 -20.975 -23.660 1.00 30.55  ? 179 MET A CE  1 
ATOM   1443  N N   . LEU A 1 180 ? -20.508 -17.181 -23.611 1.00 25.62  ? 180 LEU A N   1 
ATOM   1444  C CA  . LEU A 1 180 ? -20.090 -16.376 -24.735 1.00 27.00  ? 180 LEU A CA  1 
ATOM   1445  C C   . LEU A 1 180 ? -20.187 -14.895 -24.393 1.00 28.77  ? 180 LEU A C   1 
ATOM   1446  O O   . LEU A 1 180 ? -19.308 -14.114 -24.784 1.00 30.52  ? 180 LEU A O   1 
ATOM   1447  C CB  . LEU A 1 180 ? -20.950 -16.690 -25.965 1.00 28.73  ? 180 LEU A CB  1 
ATOM   1448  C CG  . LEU A 1 180 ? -20.625 -17.983 -26.708 1.00 28.83  ? 180 LEU A CG  1 
ATOM   1449  C CD1 . LEU A 1 180 ? -21.650 -18.211 -27.826 1.00 29.06  ? 180 LEU A CD1 1 
ATOM   1450  C CD2 . LEU A 1 180 ? -19.225 -17.963 -27.310 1.00 26.74  ? 180 LEU A CD2 1 
ATOM   1451  N N   . ALA A 1 181 ? -21.256 -14.508 -23.688 1.00 28.10  ? 181 ALA A N   1 
ATOM   1452  C CA  . ALA A 1 181 ? -21.400 -13.105 -23.324 1.00 30.95  ? 181 ALA A CA  1 
ATOM   1453  C C   . ALA A 1 181 ? -20.290 -12.657 -22.348 1.00 29.74  ? 181 ALA A C   1 
ATOM   1454  O O   . ALA A 1 181 ? -19.794 -11.527 -22.426 1.00 28.74  ? 181 ALA A O   1 
ATOM   1455  C CB  . ALA A 1 181 ? -22.789 -12.870 -22.794 1.00 30.14  ? 181 ALA A CB  1 
ATOM   1456  N N   . ALA A 1 182 ? -19.852 -13.570 -21.487 1.00 26.62  ? 182 ALA A N   1 
ATOM   1457  C CA  . ALA A 1 182 ? -18.811 -13.324 -20.496 1.00 27.50  ? 182 ALA A CA  1 
ATOM   1458  C C   . ALA A 1 182 ? -17.395 -13.280 -21.080 1.00 29.04  ? 182 ALA A C   1 
ATOM   1459  O O   . ALA A 1 182 ? -16.570 -12.517 -20.594 1.00 28.20  ? 182 ALA A O   1 
ATOM   1460  C CB  . ALA A 1 182 ? -18.889 -14.409 -19.448 1.00 29.13  ? 182 ALA A CB  1 
ATOM   1461  N N   . LEU A 1 183 ? -17.095 -14.038 -22.148 1.00 26.74  ? 183 LEU A N   1 
ATOM   1462  C CA  . LEU A 1 183 ? -15.727 -14.120 -22.637 1.00 26.38  ? 183 LEU A CA  1 
ATOM   1463  C C   . LEU A 1 183 ? -15.107 -12.755 -22.943 1.00 27.15  ? 183 LEU A C   1 
ATOM   1464  O O   . LEU A 1 183 ? -13.964 -12.523 -22.537 1.00 28.02  ? 183 LEU A O   1 
ATOM   1465  C CB  . LEU A 1 183 ? -15.637 -15.040 -23.859 1.00 26.47  ? 183 LEU A CB  1 
ATOM   1466  C CG  . LEU A 1 183 ? -15.964 -16.511 -23.612 1.00 29.02  ? 183 LEU A CG  1 
ATOM   1467  C CD1 . LEU A 1 183 ? -15.525 -17.356 -24.794 1.00 28.15  ? 183 LEU A CD1 1 
ATOM   1468  C CD2 . LEU A 1 183 ? -15.335 -17.010 -22.324 1.00 29.23  ? 183 LEU A CD2 1 
ATOM   1469  N N   . PRO A 1 184 ? -15.739 -11.821 -23.690 1.00 26.29  ? 184 PRO A N   1 
ATOM   1470  C CA  . PRO A 1 184 ? -15.114 -10.532 -23.939 1.00 26.59  ? 184 PRO A CA  1 
ATOM   1471  C C   . PRO A 1 184 ? -14.849 -9.712  -22.674 1.00 26.61  ? 184 PRO A C   1 
ATOM   1472  O O   . PRO A 1 184 ? -13.858 -9.001  -22.605 1.00 26.67  ? 184 PRO A O   1 
ATOM   1473  C CB  . PRO A 1 184 ? -16.075 -9.763  -24.856 1.00 26.69  ? 184 PRO A CB  1 
ATOM   1474  C CG  . PRO A 1 184 ? -17.098 -10.774 -25.320 1.00 30.58  ? 184 PRO A CG  1 
ATOM   1475  C CD  . PRO A 1 184 ? -16.982 -12.006 -24.457 1.00 29.22  ? 184 PRO A CD  1 
ATOM   1476  N N   . VAL A 1 185 ? -15.736 -9.820  -21.681 1.00 26.06  ? 185 VAL A N   1 
ATOM   1477  C CA  . VAL A 1 185 ? -15.570 -9.099  -20.434 1.00 26.54  ? 185 VAL A CA  1 
ATOM   1478  C C   . VAL A 1 185 ? -14.340 -9.639  -19.704 1.00 27.26  ? 185 VAL A C   1 
ATOM   1479  O O   . VAL A 1 185 ? -13.551 -8.857  -19.191 1.00 24.18  ? 185 VAL A O   1 
ATOM   1480  C CB  . VAL A 1 185 ? -16.813 -9.181  -19.546 1.00 26.64  ? 185 VAL A CB  1 
ATOM   1481  C CG1 . VAL A 1 185 ? -16.597 -8.507  -18.198 1.00 26.72  ? 185 VAL A CG1 1 
ATOM   1482  C CG2 . VAL A 1 185 ? -18.017 -8.610  -20.262 1.00 32.07  ? 185 VAL A CG2 1 
ATOM   1483  N N   . ILE A 1 186 ? -14.206 -10.954 -19.646 1.00 26.64  ? 186 ILE A N   1 
ATOM   1484  C CA  . ILE A 1 186 ? -13.069 -11.593 -18.986 1.00 26.78  ? 186 ILE A CA  1 
ATOM   1485  C C   . ILE A 1 186 ? -11.785 -11.248 -19.729 1.00 26.21  ? 186 ILE A C   1 
ATOM   1486  O O   . ILE A 1 186 ? -10.777 -10.918 -19.105 1.00 26.58  ? 186 ILE A O   1 
ATOM   1487  C CB  . ILE A 1 186 ? -13.290 -13.114 -18.852 1.00 25.78  ? 186 ILE A CB  1 
ATOM   1488  C CG1 . ILE A 1 186 ? -14.442 -13.419 -17.895 1.00 28.02  ? 186 ILE A CG1 1 
ATOM   1489  C CG2 . ILE A 1 186 ? -12.036 -13.843 -18.407 1.00 25.82  ? 186 ILE A CG2 1 
ATOM   1490  C CD1 . ILE A 1 186 ? -15.023 -14.858 -17.994 1.00 29.80  ? 186 ILE A CD1 1 
ATOM   1491  N N   . ALA A 1 187 ? -11.801 -11.400 -21.061 1.00 24.91  ? 187 ALA A N   1 
ATOM   1492  C CA  . ALA A 1 187 ? -10.633 -11.142 -21.868 1.00 24.71  ? 187 ALA A CA  1 
ATOM   1493  C C   . ALA A 1 187 ? -10.186 -9.694  -21.695 1.00 25.15  ? 187 ALA A C   1 
ATOM   1494  O O   . ALA A 1 187 ? -8.997  -9.450  -21.569 1.00 23.68  ? 187 ALA A O   1 
ATOM   1495  C CB  . ALA A 1 187 ? -10.886 -11.440 -23.340 1.00 24.76  ? 187 ALA A CB  1 
ATOM   1496  N N   . ALA A 1 188 ? -11.122 -8.739  -21.793 1.00 23.76  ? 188 ALA A N   1 
ATOM   1497  C CA  . ALA A 1 188 ? -10.788 -7.326  -21.657 1.00 22.01  ? 188 ALA A CA  1 
ATOM   1498  C C   . ALA A 1 188 ? -10.241 -7.054  -20.261 1.00 23.98  ? 188 ALA A C   1 
ATOM   1499  O O   . ALA A 1 188 ? -9.285  -6.279  -20.102 1.00 23.37  ? 188 ALA A O   1 
ATOM   1500  C CB  . ALA A 1 188 ? -12.016 -6.486  -21.940 1.00 24.08  ? 188 ALA A CB  1 
ATOM   1501  N N   . TYR A 1 189 ? -10.836 -7.711  -19.254 1.00 22.68  ? 189 TYR A N   1 
ATOM   1502  C CA  . TYR A 1 189 ? -10.384 -7.481  -17.894 1.00 26.24  ? 189 TYR A CA  1 
ATOM   1503  C C   . TYR A 1 189 ? -8.895  -7.819  -17.792 1.00 25.13  ? 189 TYR A C   1 
ATOM   1504  O O   . TYR A 1 189 ? -8.111  -7.064  -17.210 1.00 23.04  ? 189 TYR A O   1 
ATOM   1505  C CB  . TYR A 1 189 ? -11.198 -8.270  -16.868 1.00 25.34  ? 189 TYR A CB  1 
ATOM   1506  C CG  . TYR A 1 189 ? -10.948 -7.822  -15.445 1.00 27.77  ? 189 TYR A CG  1 
ATOM   1507  C CD1 . TYR A 1 189 ? -11.650 -6.752  -14.910 1.00 29.04  ? 189 TYR A CD1 1 
ATOM   1508  C CD2 . TYR A 1 189 ? -9.982  -8.426  -14.658 1.00 28.28  ? 189 TYR A CD2 1 
ATOM   1509  C CE1 . TYR A 1 189 ? -11.411 -6.292  -13.630 1.00 27.61  ? 189 TYR A CE1 1 
ATOM   1510  C CE2 . TYR A 1 189 ? -9.733  -7.978  -13.371 1.00 31.78  ? 189 TYR A CE2 1 
ATOM   1511  C CZ  . TYR A 1 189 ? -10.460 -6.918  -12.863 1.00 31.76  ? 189 TYR A CZ  1 
ATOM   1512  O OH  . TYR A 1 189 ? -10.229 -6.442  -11.601 1.00 42.97  ? 189 TYR A OH  1 
ATOM   1513  N N   . ILE A 1 190 ? -8.535  -8.995  -18.318 1.00 25.69  ? 190 ILE A N   1 
ATOM   1514  C CA  . ILE A 1 190 ? -7.168  -9.457  -18.365 1.00 25.56  ? 190 ILE A CA  1 
ATOM   1515  C C   . ILE A 1 190 ? -6.309  -8.429  -19.092 1.00 25.91  ? 190 ILE A C   1 
ATOM   1516  O O   . ILE A 1 190 ? -5.256  -8.041  -18.586 1.00 23.80  ? 190 ILE A O   1 
ATOM   1517  C CB  . ILE A 1 190 ? -7.105  -10.875 -18.980 1.00 26.73  ? 190 ILE A CB  1 
ATOM   1518  C CG1 . ILE A 1 190 ? -7.773  -11.917 -18.082 1.00 26.21  ? 190 ILE A CG1 1 
ATOM   1519  C CG2 . ILE A 1 190 ? -5.684  -11.298 -19.279 1.00 26.67  ? 190 ILE A CG2 1 
ATOM   1520  C CD1 . ILE A 1 190 ? -8.084  -13.192 -18.795 1.00 27.38  ? 190 ILE A CD1 1 
ATOM   1521  N N   . TYR A 1 191 ? -6.754  -8.017  -20.285 1.00 25.63  ? 191 TYR A N   1 
ATOM   1522  C CA  . TYR A 1 191 ? -5.986  -7.103  -21.114 1.00 24.59  ? 191 TYR A CA  1 
ATOM   1523  C C   . TYR A 1 191 ? -5.717  -5.792  -20.373 1.00 27.00  ? 191 TYR A C   1 
ATOM   1524  O O   . TYR A 1 191 ? -4.590  -5.279  -20.333 1.00 23.25  ? 191 TYR A O   1 
ATOM   1525  C CB  . TYR A 1 191 ? -6.748  -6.839  -22.415 1.00 24.85  ? 191 TYR A CB  1 
ATOM   1526  C CG  . TYR A 1 191 ? -5.968  -6.036  -23.418 1.00 28.21  ? 191 TYR A CG  1 
ATOM   1527  C CD1 . TYR A 1 191 ? -4.949  -6.620  -24.152 1.00 26.97  ? 191 TYR A CD1 1 
ATOM   1528  C CD2 . TYR A 1 191 ? -6.198  -4.680  -23.587 1.00 25.35  ? 191 TYR A CD2 1 
ATOM   1529  C CE1 . TYR A 1 191 ? -4.243  -5.888  -25.101 1.00 28.51  ? 191 TYR A CE1 1 
ATOM   1530  C CE2 . TYR A 1 191 ? -5.466  -3.927  -24.488 1.00 27.56  ? 191 TYR A CE2 1 
ATOM   1531  C CZ  . TYR A 1 191 ? -4.483  -4.535  -25.244 1.00 30.40  ? 191 TYR A CZ  1 
ATOM   1532  O OH  . TYR A 1 191 ? -3.746  -3.782  -26.116 1.00 31.53  ? 191 TYR A OH  1 
ATOM   1533  N N   . ARG A 1 192 ? -6.767  -5.238  -19.760 1.00 24.16  ? 192 ARG A N   1 
ATOM   1534  C CA  . ARG A 1 192 ? -6.629  -3.960  -19.083 1.00 24.97  ? 192 ARG A CA  1 
ATOM   1535  C C   . ARG A 1 192 ? -5.741  -4.075  -17.842 1.00 27.23  ? 192 ARG A C   1 
ATOM   1536  O O   . ARG A 1 192 ? -4.925  -3.178  -17.565 1.00 25.87  ? 192 ARG A O   1 
ATOM   1537  C CB  . ARG A 1 192 ? -8.017  -3.413  -18.711 1.00 23.84  ? 192 ARG A CB  1 
ATOM   1538  C CG  . ARG A 1 192 ? -8.914  -3.100  -19.900 1.00 23.81  ? 192 ARG A CG  1 
ATOM   1539  C CD  . ARG A 1 192 ? -8.320  -2.084  -20.859 1.00 24.57  ? 192 ARG A CD  1 
ATOM   1540  N NE  . ARG A 1 192 ? -8.207  -0.780  -20.228 1.00 26.20  ? 192 ARG A NE  1 
ATOM   1541  C CZ  . ARG A 1 192 ? -7.857  0.318   -20.875 1.00 28.60  ? 192 ARG A CZ  1 
ATOM   1542  N NH1 . ARG A 1 192 ? -7.596  0.273   -22.161 1.00 28.90  ? 192 ARG A NH1 1 
ATOM   1543  N NH2 . ARG A 1 192 ? -7.691  1.439   -20.218 1.00 29.49  ? 192 ARG A NH2 1 
ATOM   1544  N N   . ARG A 1 193 ? -5.906  -5.168  -17.094 1.00 24.05  ? 193 ARG A N   1 
ATOM   1545  C CA  . ARG A 1 193 ? -5.178  -5.332  -15.852 1.00 25.03  ? 193 ARG A CA  1 
ATOM   1546  C C   . ARG A 1 193 ? -3.695  -5.528  -16.144 1.00 26.06  ? 193 ARG A C   1 
ATOM   1547  O O   . ARG A 1 193 ? -2.868  -4.941  -15.462 1.00 25.37  ? 193 ARG A O   1 
ATOM   1548  C CB  . ARG A 1 193 ? -5.710  -6.497  -15.023 1.00 26.15  ? 193 ARG A CB  1 
ATOM   1549  C CG  . ARG A 1 193 ? -5.012  -6.615  -13.675 1.00 27.12  ? 193 ARG A CG  1 
ATOM   1550  C CD  . ARG A 1 193 ? -5.538  -7.706  -12.796 1.00 27.93  ? 193 ARG A CD  1 
ATOM   1551  N NE  . ARG A 1 193 ? -4.780  -7.802  -11.549 1.00 28.82  ? 193 ARG A NE  1 
ATOM   1552  C CZ  . ARG A 1 193 ? -4.236  -8.914  -11.070 1.00 27.74  ? 193 ARG A CZ  1 
ATOM   1553  N NH1 . ARG A 1 193 ? -4.431  -10.085 -11.672 1.00 25.33  ? 193 ARG A NH1 1 
ATOM   1554  N NH2 . ARG A 1 193 ? -3.479  -8.833  -9.992  1.00 26.99  ? 193 ARG A NH2 1 
ATOM   1555  N N   . LYS A 1 194 ? -3.355  -6.347  -17.158 1.00 25.91  ? 194 LYS A N   1 
ATOM   1556  C CA  . LYS A 1 194 ? -1.966  -6.649  -17.434 1.00 26.75  ? 194 LYS A CA  1 
ATOM   1557  C C   . LYS A 1 194 ? -1.269  -5.506  -18.151 1.00 28.28  ? 194 LYS A C   1 
ATOM   1558  O O   . LYS A 1 194 ? -0.119  -5.216  -17.862 1.00 26.21  ? 194 LYS A O   1 
ATOM   1559  C CB  . LYS A 1 194 ? -1.790  -7.885  -18.317 1.00 28.30  ? 194 LYS A CB  1 
ATOM   1560  C CG  . LYS A 1 194 ? -2.069  -9.212  -17.633 1.00 25.92  ? 194 LYS A CG  1 
ATOM   1561  C CD  . LYS A 1 194 ? -1.694  -10.393 -18.520 1.00 27.42  ? 194 LYS A CD  1 
ATOM   1562  C CE  . LYS A 1 194 ? -0.213  -10.623 -18.728 1.00 27.03  ? 194 LYS A CE  1 
ATOM   1563  N NZ  . LYS A 1 194 ? 0.513   -11.070 -17.518 1.00 28.18  ? 194 LYS A NZ  1 
ATOM   1564  N N   . TYR A 1 195 ? -1.939  -4.879  -19.113 1.00 28.60  ? 195 TYR A N   1 
ATOM   1565  C CA  . TYR A 1 195 ? -1.199  -4.094  -20.087 1.00 28.07  ? 195 TYR A CA  1 
ATOM   1566  C C   . TYR A 1 195 ? -1.633  -2.632  -20.107 1.00 28.29  ? 195 TYR A C   1 
ATOM   1567  O O   . TYR A 1 195 ? -0.967  -1.827  -20.746 1.00 28.47  ? 195 TYR A O   1 
ATOM   1568  C CB  . TYR A 1 195 ? -1.382  -4.681  -21.495 1.00 26.59  ? 195 TYR A CB  1 
ATOM   1569  C CG  . TYR A 1 195 ? -1.095  -6.159  -21.623 1.00 25.61  ? 195 TYR A CG  1 
ATOM   1570  C CD1 . TYR A 1 195 ? 0.183   -6.665  -21.418 1.00 29.24  ? 195 TYR A CD1 1 
ATOM   1571  C CD2 . TYR A 1 195 ? -2.078  -7.050  -21.984 1.00 26.95  ? 195 TYR A CD2 1 
ATOM   1572  C CE1 . TYR A 1 195 ? 0.452   -8.018  -21.524 1.00 26.40  ? 195 TYR A CE1 1 
ATOM   1573  C CE2 . TYR A 1 195 ? -1.834  -8.411  -22.086 1.00 27.16  ? 195 TYR A CE2 1 
ATOM   1574  C CZ  . TYR A 1 195 ? -0.555  -8.892  -21.880 1.00 27.11  ? 195 TYR A CZ  1 
ATOM   1575  O OH  . TYR A 1 195 ? -0.359  -10.238 -22.022 1.00 26.82  ? 195 TYR A OH  1 
ATOM   1576  N N   . LYS A 1 196 ? -2.771  -2.260  -19.510 1.00 27.41  ? 196 LYS A N   1 
ATOM   1577  C CA  . LYS A 1 196 ? -3.232  -0.888  -19.691 1.00 27.86  ? 196 LYS A CA  1 
ATOM   1578  C C   . LYS A 1 196 ? -3.477  -0.243  -18.336 1.00 31.30  ? 196 LYS A C   1 
ATOM   1579  O O   . LYS A 1 196 ? -4.349  0.595   -18.188 1.00 28.64  ? 196 LYS A O   1 
ATOM   1580  C CB  . LYS A 1 196 ? -4.495  -0.875  -20.554 1.00 29.31  ? 196 LYS A CB  1 
ATOM   1581  C CG  . LYS A 1 196 ? -4.335  -1.460  -21.951 1.00 29.79  ? 196 LYS A CG  1 
ATOM   1582  C CD  . LYS A 1 196 ? -3.457  -0.585  -22.813 1.00 36.43  ? 196 LYS A CD  1 
ATOM   1583  C CE  . LYS A 1 196 ? -3.032  -1.251  -24.101 1.00 40.17  ? 196 LYS A CE  1 
ATOM   1584  N NZ  . LYS A 1 196 ? -2.345  -0.295  -24.999 1.00 44.05  ? 196 LYS A NZ  1 
ATOM   1585  N N   . GLY A 1 197 ? -2.705  -0.634  -17.343 1.00 27.94  ? 197 GLY A N   1 
ATOM   1586  C CA  . GLY A 1 197 ? -2.689  0.087   -16.089 1.00 30.52  ? 197 GLY A CA  1 
ATOM   1587  C C   . GLY A 1 197 ? -3.924  -0.129  -15.223 1.00 29.76  ? 197 GLY A C   1 
ATOM   1588  O O   . GLY A 1 197 ? -4.202  0.695   -14.360 1.00 28.88  ? 197 GLY A O   1 
ATOM   1589  N N   . ASP A 1 198 ? -4.607  -1.267  -15.396 1.00 27.16  ? 198 ASP A N   1 
ATOM   1590  C CA  . ASP A 1 198 ? -5.628  -1.718  -14.468 1.00 25.89  ? 198 ASP A CA  1 
ATOM   1591  C C   . ASP A 1 198 ? -6.753  -0.689  -14.341 1.00 24.30  ? 198 ASP A C   1 
ATOM   1592  O O   . ASP A 1 198 ? -7.274  -0.454  -13.246 1.00 28.23  ? 198 ASP A O   1 
ATOM   1593  C CB  . ASP A 1 198 ? -4.989  -2.032  -13.107 1.00 25.83  ? 198 ASP A CB  1 
ATOM   1594  C CG  . ASP A 1 198 ? -5.792  -2.944  -12.204 1.00 26.85  ? 198 ASP A CG  1 
ATOM   1595  O OD1 . ASP A 1 198 ? -6.723  -3.664  -12.701 1.00 28.16  ? 198 ASP A OD1 1 
ATOM   1596  O OD2 . ASP A 1 198 ? -5.490  -2.932  -11.009 1.00 25.41  ? 198 ASP A OD2 1 
ATOM   1597  N N   . THR A 1 199 ? -7.125  -0.093  -15.474 1.00 27.39  ? 199 THR A N   1 
ATOM   1598  C CA  . THR A 1 199 ? -8.296  0.751   -15.577 1.00 27.36  ? 199 THR A CA  1 
ATOM   1599  C C   . THR A 1 199 ? -9.247  0.015   -16.495 1.00 29.96  ? 199 THR A C   1 
ATOM   1600  O O   . THR A 1 199 ? -8.807  -0.525  -17.504 1.00 30.95  ? 199 THR A O   1 
ATOM   1601  C CB  . THR A 1 199 ? -7.937  2.161   -16.063 1.00 30.56  ? 199 THR A CB  1 
ATOM   1602  O OG1 . THR A 1 199 ? -7.324  2.109   -17.348 1.00 33.65  ? 199 THR A OG1 1 
ATOM   1603  C CG2 . THR A 1 199 ? -6.973  2.841   -15.111 1.00 35.30  ? 199 THR A CG2 1 
ATOM   1604  N N   . HIS A 1 200 ? -10.514 -0.038  -16.090 1.00 28.54  ? 200 HIS A N   1 
ATOM   1605  C CA  . HIS A 1 200 ? -11.508 -0.925  -16.672 1.00 32.51  ? 200 HIS A CA  1 
ATOM   1606  C C   . HIS A 1 200 ? -12.621 -0.116  -17.336 1.00 38.69  ? 200 HIS A C   1 
ATOM   1607  O O   . HIS A 1 200 ? -13.054 0.894   -16.801 1.00 36.70  ? 200 HIS A O   1 
ATOM   1608  C CB  . HIS A 1 200 ? -11.992 -1.897  -15.596 1.00 32.38  ? 200 HIS A CB  1 
ATOM   1609  C CG  . HIS A 1 200 ? -10.830 -2.676  -15.114 1.00 28.78  ? 200 HIS A CG  1 
ATOM   1610  N ND1 . HIS A 1 200 ? -10.416 -3.780  -15.815 1.00 24.44  ? 200 HIS A ND1 1 
ATOM   1611  C CD2 . HIS A 1 200 ? -9.976  -2.532  -14.088 1.00 28.26  ? 200 HIS A CD2 1 
ATOM   1612  C CE1 . HIS A 1 200 ? -9.321  -4.277  -15.232 1.00 27.93  ? 200 HIS A CE1 1 
ATOM   1613  N NE2 . HIS A 1 200 ? -9.026  -3.526  -14.178 1.00 26.09  ? 200 HIS A NE2 1 
ATOM   1614  N N   . ILE A 1 201 ? -13.033 -0.584  -18.522 1.00 34.53  ? 201 ILE A N   1 
ATOM   1615  C CA  . ILE A 1 201 ? -14.031 0.022   -19.379 1.00 32.33  ? 201 ILE A CA  1 
ATOM   1616  C C   . ILE A 1 201 ? -15.203 -0.950  -19.443 1.00 33.49  ? 201 ILE A C   1 
ATOM   1617  O O   . ILE A 1 201 ? -15.046 -2.135  -19.795 1.00 29.63  ? 201 ILE A O   1 
ATOM   1618  C CB  . ILE A 1 201 ? -13.432 0.326   -20.775 1.00 31.83  ? 201 ILE A CB  1 
ATOM   1619  C CG1 . ILE A 1 201 ? -12.177 1.205   -20.676 1.00 33.35  ? 201 ILE A CG1 1 
ATOM   1620  C CG2 . ILE A 1 201 ? -14.477 0.927   -21.727 1.00 31.86  ? 201 ILE A CG2 1 
ATOM   1621  C CD1 . ILE A 1 201 ? -11.301 1.198   -21.914 1.00 33.89  ? 201 ILE A CD1 1 
ATOM   1622  N N   . ALA A 1 202 ? -16.386 -0.422  -19.122 1.00 33.36  ? 202 ALA A N   1 
ATOM   1623  C CA  . ALA A 1 202 ? -17.624 -1.182  -19.075 1.00 35.13  ? 202 ALA A CA  1 
ATOM   1624  C C   . ALA A 1 202 ? -18.067 -1.562  -20.494 1.00 28.51  ? 202 ALA A C   1 
ATOM   1625  O O   . ALA A 1 202 ? -17.734 -0.867  -21.443 1.00 31.15  ? 202 ALA A O   1 
ATOM   1626  C CB  . ALA A 1 202 ? -18.689 -0.325  -18.385 1.00 38.27  ? 202 ALA A CB  1 
ATOM   1627  N N   . PRO A 1 203 ? -18.863 -2.647  -20.666 1.00 32.89  ? 203 PRO A N   1 
ATOM   1628  C CA  . PRO A 1 203 ? -19.431 -2.994  -21.959 1.00 33.56  ? 203 PRO A CA  1 
ATOM   1629  C C   . PRO A 1 203 ? -20.327 -1.864  -22.453 1.00 36.03  ? 203 PRO A C   1 
ATOM   1630  O O   . PRO A 1 203 ? -20.970 -1.186  -21.660 1.00 35.84  ? 203 PRO A O   1 
ATOM   1631  C CB  . PRO A 1 203 ? -20.333 -4.211  -21.721 1.00 34.37  ? 203 PRO A CB  1 
ATOM   1632  C CG  . PRO A 1 203 ? -20.012 -4.696  -20.314 1.00 37.47  ? 203 PRO A CG  1 
ATOM   1633  C CD  . PRO A 1 203 ? -19.262 -3.591  -19.615 1.00 33.05  ? 203 PRO A CD  1 
ATOM   1634  N N   . ASP A 1 204 ? -20.382 -1.703  -23.764 1.00 37.88  ? 204 ASP A N   1 
ATOM   1635  C CA  . ASP A 1 204 ? -21.291 -0.751  -24.375 1.00 38.41  ? 204 ASP A CA  1 
ATOM   1636  C C   . ASP A 1 204 ? -22.557 -1.501  -24.788 1.00 40.72  ? 204 ASP A C   1 
ATOM   1637  O O   . ASP A 1 204 ? -22.497 -2.338  -25.672 1.00 39.43  ? 204 ASP A O   1 
ATOM   1638  C CB  . ASP A 1 204 ? -20.601 -0.057  -25.544 1.00 40.53  ? 204 ASP A CB  1 
ATOM   1639  C CG  . ASP A 1 204 ? -21.459 0.976   -26.266 1.00 47.73  ? 204 ASP A CG  1 
ATOM   1640  O OD1 . ASP A 1 204 ? -22.721 0.948   -26.100 1.00 43.70  ? 204 ASP A OD1 1 
ATOM   1641  O OD2 . ASP A 1 204 ? -20.858 1.799   -26.990 1.00 44.47  ? 204 ASP A OD2 1 
ATOM   1642  N N   . PRO A 1 205 ? -23.750 -1.194  -24.227 1.00 41.25  ? 205 PRO A N   1 
ATOM   1643  C CA  . PRO A 1 205 ? -24.977 -1.888  -24.619 1.00 44.59  ? 205 PRO A CA  1 
ATOM   1644  C C   . PRO A 1 205 ? -25.382 -1.740  -26.079 1.00 39.34  ? 205 PRO A C   1 
ATOM   1645  O O   . PRO A 1 205 ? -26.193 -2.520  -26.542 1.00 45.92  ? 205 PRO A O   1 
ATOM   1646  C CB  . PRO A 1 205 ? -26.077 -1.292  -23.718 1.00 48.35  ? 205 PRO A CB  1 
ATOM   1647  C CG  . PRO A 1 205 ? -25.323 -0.624  -22.585 1.00 46.99  ? 205 PRO A CG  1 
ATOM   1648  C CD  . PRO A 1 205 ? -23.998 -0.184  -23.183 1.00 46.62  ? 205 PRO A CD  1 
ATOM   1649  N N   . ASN A 1 206 ? -24.803 -0.810  -26.836 1.00 39.00  ? 206 ASN A N   1 
ATOM   1650  C CA  . ASN A 1 206 ? -25.245 -0.631  -28.211 1.00 43.05  ? 206 ASN A CA  1 
ATOM   1651  C C   . ASN A 1 206 ? -24.230 -1.184  -29.217 1.00 46.04  ? 206 ASN A C   1 
ATOM   1652  O O   . ASN A 1 206 ? -24.457 -1.096  -30.416 1.00 45.44  ? 206 ASN A O   1 
ATOM   1653  C CB  . ASN A 1 206 ? -25.581 0.839   -28.502 1.00 56.00  ? 206 ASN A CB  1 
ATOM   1654  C CG  . ASN A 1 206 ? -26.606 1.400   -27.532 1.00 55.30  ? 206 ASN A CG  1 
ATOM   1655  O OD1 . ASN A 1 206 ? -27.638 0.786   -27.286 1.00 54.74  ? 206 ASN A OD1 1 
ATOM   1656  N ND2 . ASN A 1 206 ? -26.288 2.512   -26.892 1.00 69.50  ? 206 ASN A ND2 1 
ATOM   1657  N N   . LEU A 1 207 ? -23.135 -1.805  -28.774 1.00 37.91  ? 207 LEU A N   1 
ATOM   1658  C CA  . LEU A 1 207 ? -22.231 -2.433  -29.733 1.00 38.53  ? 207 LEU A CA  1 
ATOM   1659  C C   . LEU A 1 207 ? -22.527 -3.921  -29.826 1.00 35.40  ? 207 LEU A C   1 
ATOM   1660  O O   . LEU A 1 207 ? -23.056 -4.507  -28.899 1.00 31.92  ? 207 LEU A O   1 
ATOM   1661  C CB  . LEU A 1 207 ? -20.778 -2.238  -29.312 1.00 38.18  ? 207 LEU A CB  1 
ATOM   1662  C CG  . LEU A 1 207 ? -20.290 -0.804  -29.335 1.00 40.71  ? 207 LEU A CG  1 
ATOM   1663  C CD1 . LEU A 1 207 ? -18.892 -0.719  -28.739 1.00 43.12  ? 207 LEU A CD1 1 
ATOM   1664  C CD2 . LEU A 1 207 ? -20.344 -0.257  -30.743 1.00 40.53  ? 207 LEU A CD2 1 
ATOM   1665  N N   . ASP A 1 208 ? -22.187 -4.483  -30.980 1.00 36.69  ? 208 ASP A N   1 
ATOM   1666  C CA  . ASP A 1 208 ? -22.175 -5.917  -31.201 1.00 37.33  ? 208 ASP A CA  1 
ATOM   1667  C C   . ASP A 1 208 ? -21.007 -6.555  -30.420 1.00 37.31  ? 208 ASP A C   1 
ATOM   1668  O O   . ASP A 1 208 ? -20.173 -5.860  -29.860 1.00 33.70  ? 208 ASP A O   1 
ATOM   1669  C CB  . ASP A 1 208 ? -22.056 -6.154  -32.706 1.00 34.85  ? 208 ASP A CB  1 
ATOM   1670  C CG  . ASP A 1 208 ? -20.830 -5.534  -33.365 1.00 38.32  ? 208 ASP A CG  1 
ATOM   1671  O OD1 . ASP A 1 208 ? -20.855 -4.306  -33.630 1.00 40.30  ? 208 ASP A OD1 1 
ATOM   1672  O OD2 . ASP A 1 208 ? -19.852 -6.283  -33.648 1.00 36.22  ? 208 ASP A OD2 1 
ATOM   1673  N N   . TRP A 1 209 ? -20.924 -7.887  -30.457 1.00 35.12  ? 209 TRP A N   1 
ATOM   1674  C CA  . TRP A 1 209 ? -20.083 -8.700  -29.587 1.00 32.84  ? 209 TRP A CA  1 
ATOM   1675  C C   . TRP A 1 209 ? -18.592 -8.429  -29.791 1.00 32.37  ? 209 TRP A C   1 
ATOM   1676  O O   . TRP A 1 209 ? -17.893 -8.186  -28.816 1.00 30.09  ? 209 TRP A O   1 
ATOM   1677  C CB  . TRP A 1 209 ? -20.441 -10.164 -29.825 1.00 32.15  ? 209 TRP A CB  1 
ATOM   1678  C CG  . TRP A 1 209 ? -19.821 -11.183 -28.918 1.00 31.35  ? 209 TRP A CG  1 
ATOM   1679  C CD1 . TRP A 1 209 ? -20.095 -11.467 -27.605 1.00 30.47  ? 209 TRP A CD1 1 
ATOM   1680  C CD2 . TRP A 1 209 ? -18.838 -12.131 -29.333 1.00 28.15  ? 209 TRP A CD2 1 
ATOM   1681  N NE1 . TRP A 1 209 ? -19.361 -12.558 -27.194 1.00 29.77  ? 209 TRP A NE1 1 
ATOM   1682  C CE2 . TRP A 1 209 ? -18.591 -12.989 -28.239 1.00 28.77  ? 209 TRP A CE2 1 
ATOM   1683  C CE3 . TRP A 1 209 ? -18.208 -12.380 -30.558 1.00 29.78  ? 209 TRP A CE3 1 
ATOM   1684  C CZ2 . TRP A 1 209 ? -17.692 -14.050 -28.336 1.00 28.90  ? 209 TRP A CZ2 1 
ATOM   1685  C CZ3 . TRP A 1 209 ? -17.336 -13.433 -30.653 1.00 31.74  ? 209 TRP A CZ3 1 
ATOM   1686  C CH2 . TRP A 1 209 ? -17.084 -14.255 -29.554 1.00 29.12  ? 209 TRP A CH2 1 
ATOM   1687  N N   . SER A 1 210 ? -18.120 -8.478  -31.049 1.00 29.32  ? 210 SER A N   1 
ATOM   1688  C CA  . SER A 1 210 ? -16.732 -8.242  -31.413 1.00 31.56  ? 210 SER A CA  1 
ATOM   1689  C C   . SER A 1 210 ? -16.315 -6.817  -31.077 1.00 35.08  ? 210 SER A C   1 
ATOM   1690  O O   . SER A 1 210 ? -15.230 -6.585  -30.542 1.00 30.67  ? 210 SER A O   1 
ATOM   1691  C CB  . SER A 1 210 ? -16.503 -8.432  -32.901 1.00 32.99  ? 210 SER A CB  1 
ATOM   1692  O OG  . SER A 1 210 ? -16.978 -9.677  -33.331 1.00 33.03  ? 210 SER A OG  1 
ATOM   1693  N N   . ALA A 1 211 ? -17.139 -5.858  -31.520 1.00 34.79  ? 211 ALA A N   1 
ATOM   1694  C CA  . ALA A 1 211 ? -16.869 -4.443  -31.311 1.00 34.27  ? 211 ALA A CA  1 
ATOM   1695  C C   . ALA A 1 211 ? -16.764 -4.157  -29.819 1.00 30.44  ? 211 ALA A C   1 
ATOM   1696  O O   . ALA A 1 211 ? -15.953 -3.338  -29.384 1.00 32.03  ? 211 ALA A O   1 
ATOM   1697  C CB  . ALA A 1 211 ? -17.936 -3.581  -31.975 1.00 36.39  ? 211 ALA A CB  1 
ATOM   1698  N N   . ASN A 1 212 ? -17.533 -4.869  -29.021 1.00 28.09  ? 212 ASN A N   1 
ATOM   1699  C CA  . ASN A 1 212 ? -17.534 -4.599  -27.603 1.00 31.00  ? 212 ASN A CA  1 
ATOM   1700  C C   . ASN A 1 212 ? -16.219 -5.043  -26.970 1.00 31.04  ? 212 ASN A C   1 
ATOM   1701  O O   . ASN A 1 212 ? -15.734 -4.402  -26.045 1.00 30.86  ? 212 ASN A O   1 
ATOM   1702  C CB  . ASN A 1 212 ? -18.668 -5.278  -26.854 1.00 33.04  ? 212 ASN A CB  1 
ATOM   1703  C CG  . ASN A 1 212 ? -19.494 -4.316  -26.038 1.00 34.82  ? 212 ASN A CG  1 
ATOM   1704  O OD1 . ASN A 1 212 ? -19.013 -3.280  -25.579 1.00 33.20  ? 212 ASN A OD1 1 
ATOM   1705  N ND2 . ASN A 1 212 ? -20.780 -4.612  -25.946 1.00 39.94  ? 212 ASN A ND2 1 
ATOM   1706  N N   . LEU A 1 213 ? -15.628 -6.118  -27.475 1.00 29.15  ? 213 LEU A N   1 
ATOM   1707  C CA  . LEU A 1 213 ? -14.330 -6.521  -26.978 1.00 29.41  ? 213 LEU A CA  1 
ATOM   1708  C C   . LEU A 1 213 ? -13.295 -5.440  -27.263 1.00 28.34  ? 213 LEU A C   1 
ATOM   1709  O O   . LEU A 1 213 ? -12.508 -5.080  -26.391 1.00 29.26  ? 213 LEU A O   1 
ATOM   1710  C CB  . LEU A 1 213 ? -13.927 -7.856  -27.599 1.00 26.86  ? 213 LEU A CB  1 
ATOM   1711  C CG  . LEU A 1 213 ? -12.512 -8.334  -27.275 1.00 27.28  ? 213 LEU A CG  1 
ATOM   1712  C CD1 . LEU A 1 213 ? -12.254 -8.427  -25.784 1.00 28.70  ? 213 LEU A CD1 1 
ATOM   1713  C CD2 . LEU A 1 213 ? -12.292 -9.687  -27.921 1.00 33.74  ? 213 LEU A CD2 1 
ATOM   1714  N N   . ALA A 1 214 ? -13.298 -4.934  -28.484 1.00 28.36  ? 214 ALA A N   1 
ATOM   1715  C CA  . ALA A 1 214 ? -12.364 -3.902  -28.886 1.00 28.86  ? 214 ALA A CA  1 
ATOM   1716  C C   . ALA A 1 214 ? -12.547 -2.667  -28.007 1.00 29.45  ? 214 ALA A C   1 
ATOM   1717  O O   . ALA A 1 214 ? -11.588 -2.117  -27.471 1.00 25.63  ? 214 ALA A O   1 
ATOM   1718  C CB  . ALA A 1 214 ? -12.561 -3.625  -30.351 1.00 29.04  ? 214 ALA A CB  1 
ATOM   1719  N N   . HIS A 1 215 ? -13.795 -2.262  -27.812 1.00 27.88  ? 215 HIS A N   1 
ATOM   1720  C CA  . HIS A 1 215 ? -14.132 -1.128  -26.975 1.00 26.31  ? 215 HIS A CA  1 
ATOM   1721  C C   . HIS A 1 215 ? -13.609 -1.342  -25.555 1.00 26.91  ? 215 HIS A C   1 
ATOM   1722  O O   . HIS A 1 215 ? -13.017 -0.446  -24.960 1.00 28.96  ? 215 HIS A O   1 
ATOM   1723  C CB  . HIS A 1 215 ? -15.654 -0.927  -26.959 1.00 25.93  ? 215 HIS A CB  1 
ATOM   1724  C CG  . HIS A 1 215 ? -16.125 0.106   -25.999 1.00 29.15  ? 215 HIS A CG  1 
ATOM   1725  N ND1 . HIS A 1 215 ? -15.866 1.447   -26.190 1.00 33.59  ? 215 HIS A ND1 1 
ATOM   1726  C CD2 . HIS A 1 215 ? -16.867 0.029   -24.889 1.00 32.12  ? 215 HIS A CD2 1 
ATOM   1727  C CE1 . HIS A 1 215 ? -16.375 2.139   -25.165 1.00 32.70  ? 215 HIS A CE1 1 
ATOM   1728  N NE2 . HIS A 1 215 ? -17.017 1.305   -24.397 1.00 33.92  ? 215 HIS A NE2 1 
ATOM   1729  N N   . MET A 1 216 ? -13.846 -2.518  -24.979 1.00 25.78  ? 216 MET A N   1 
ATOM   1730  C CA  . MET A 1 216 ? -13.489 -2.730  -23.581 1.00 27.92  ? 216 MET A CA  1 
ATOM   1731  C C   . MET A 1 216 ? -11.972 -2.863  -23.441 1.00 26.60  ? 216 MET A C   1 
ATOM   1732  O O   . MET A 1 216 ? -11.435 -2.728  -22.347 1.00 25.84  ? 216 MET A O   1 
ATOM   1733  C CB  . MET A 1 216 ? -14.167 -3.980  -23.029 1.00 26.67  ? 216 MET A CB  1 
ATOM   1734  C CG  . MET A 1 216 ? -15.651 -3.800  -22.814 1.00 29.90  ? 216 MET A CG  1 
ATOM   1735  S SD  . MET A 1 216 ? -16.428 -5.202  -22.026 1.00 32.65  ? 216 MET A SD  1 
ATOM   1736  C CE  . MET A 1 216 ? -16.326 -6.432  -23.318 1.00 32.29  ? 216 MET A CE  1 
ATOM   1737  N N   . MET A 1 217 ? -11.296 -3.167  -24.551 1.00 25.11  ? 217 MET A N   1 
ATOM   1738  C CA  . MET A 1 217 ? -9.846  -3.200  -24.551 1.00 26.16  ? 217 MET A CA  1 
ATOM   1739  C C   . MET A 1 217 ? -9.273  -1.794  -24.683 1.00 28.86  ? 217 MET A C   1 
ATOM   1740  O O   . MET A 1 217 ? -8.099  -1.594  -24.386 1.00 25.95  ? 217 MET A O   1 
ATOM   1741  C CB  . MET A 1 217 ? -9.336  -4.090  -25.678 1.00 24.89  ? 217 MET A CB  1 
ATOM   1742  C CG  . MET A 1 217 ? -9.347  -5.575  -25.298 1.00 25.10  ? 217 MET A CG  1 
ATOM   1743  S SD  . MET A 1 217 ? -9.064  -6.609  -26.768 1.00 28.33  ? 217 MET A SD  1 
ATOM   1744  C CE  . MET A 1 217 ? -7.357  -6.279  -27.171 1.00 30.05  ? 217 MET A CE  1 
ATOM   1745  N N   . GLY A 1 218 ? -10.094 -0.841  -25.159 1.00 31.32  ? 218 GLY A N   1 
ATOM   1746  C CA  . GLY A 1 218 ? -9.666  0.542   -25.290 1.00 31.44  ? 218 GLY A CA  1 
ATOM   1747  C C   . GLY A 1 218 ? -9.508  1.002   -26.737 1.00 34.43  ? 218 GLY A C   1 
ATOM   1748  O O   . GLY A 1 218 ? -8.922  2.050   -26.934 1.00 34.01  ? 218 GLY A O   1 
ATOM   1749  N N   . PHE A 1 219 ? -10.058 0.278   -27.732 1.00 30.83  ? 219 PHE A N   1 
ATOM   1750  C CA  . PHE A 1 219 ? -9.932  0.662   -29.139 1.00 32.13  ? 219 PHE A CA  1 
ATOM   1751  C C   . PHE A 1 219 ? -11.324 0.931   -29.693 1.00 36.06  ? 219 PHE A C   1 
ATOM   1752  O O   . PHE A 1 219 ? -12.160 0.026   -29.620 1.00 35.11  ? 219 PHE A O   1 
ATOM   1753  C CB  . PHE A 1 219 ? -9.290  -0.451  -29.974 1.00 32.14  ? 219 PHE A CB  1 
ATOM   1754  C CG  . PHE A 1 219 ? -7.936  -0.852  -29.465 1.00 33.35  ? 219 PHE A CG  1 
ATOM   1755  C CD1 . PHE A 1 219 ? -7.819  -1.704  -28.371 1.00 36.76  ? 219 PHE A CD1 1 
ATOM   1756  C CD2 . PHE A 1 219 ? -6.788  -0.270  -29.970 1.00 33.85  ? 219 PHE A CD2 1 
ATOM   1757  C CE1 . PHE A 1 219 ? -6.577  -2.025  -27.843 1.00 35.77  ? 219 PHE A CE1 1 
ATOM   1758  C CE2 . PHE A 1 219 ? -5.542  -0.606  -29.454 1.00 38.81  ? 219 PHE A CE2 1 
ATOM   1759  C CZ  . PHE A 1 219 ? -5.436  -1.468  -28.378 1.00 36.61  ? 219 PHE A CZ  1 
ATOM   1760  N N   . ASP A 1 220 ? -11.569 2.150   -30.237 1.00 34.32  ? 220 ASP A N   1 
ATOM   1761  C CA  . ASP A 1 220 ? -12.908 2.518   -30.713 1.00 37.29  ? 220 ASP A CA  1 
ATOM   1762  C C   . ASP A 1 220 ? -12.970 2.962   -32.177 1.00 36.42  ? 220 ASP A C   1 
ATOM   1763  O O   . ASP A 1 220 ? -14.070 3.247   -32.638 1.00 37.43  ? 220 ASP A O   1 
ATOM   1764  C CB  . ASP A 1 220 ? -13.575 3.586   -29.847 1.00 40.61  ? 220 ASP A CB  1 
ATOM   1765  C CG  . ASP A 1 220 ? -13.960 3.023   -28.499 1.00 42.25  ? 220 ASP A CG  1 
ATOM   1766  O OD1 . ASP A 1 220 ? -14.816 2.079   -28.454 1.00 43.56  ? 220 ASP A OD1 1 
ATOM   1767  O OD2 . ASP A 1 220 ? -13.384 3.489   -27.521 1.00 44.17  ? 220 ASP A OD2 1 
ATOM   1768  N N   . ASP A 1 221 ? -11.871 2.865   -32.932 1.00 34.65  ? 221 ASP A N   1 
ATOM   1769  C CA  . ASP A 1 221 ? -11.904 3.116   -34.357 1.00 39.49  ? 221 ASP A CA  1 
ATOM   1770  C C   . ASP A 1 221 ? -12.788 2.100   -35.079 1.00 40.97  ? 221 ASP A C   1 
ATOM   1771  O O   . ASP A 1 221 ? -12.717 0.887   -34.862 1.00 38.87  ? 221 ASP A O   1 
ATOM   1772  C CB  . ASP A 1 221 ? -10.519 3.065   -35.005 1.00 45.63  ? 221 ASP A CB  1 
ATOM   1773  C CG  . ASP A 1 221 ? -9.618  4.237   -34.649 1.00 57.76  ? 221 ASP A CG  1 
ATOM   1774  O OD1 . ASP A 1 221 ? -10.111 5.191   -34.014 1.00 55.40  ? 221 ASP A OD1 1 
ATOM   1775  O OD2 . ASP A 1 221 ? -8.415  4.178   -35.000 1.00 65.88  ? 221 ASP A OD2 1 
ATOM   1776  N N   . PHE A 1 222 ? -13.564 2.617   -36.022 1.00 38.74  ? 222 PHE A N   1 
ATOM   1777  C CA  . PHE A 1 222 ? -14.401 1.802   -36.880 1.00 37.95  ? 222 PHE A CA  1 
ATOM   1778  C C   . PHE A 1 222 ? -13.609 0.675   -37.533 1.00 39.73  ? 222 PHE A C   1 
ATOM   1779  O O   . PHE A 1 222 ? -14.129 -0.436  -37.629 1.00 37.62  ? 222 PHE A O   1 
ATOM   1780  C CB  . PHE A 1 222 ? -15.034 2.662   -37.973 1.00 46.87  ? 222 PHE A CB  1 
ATOM   1781  C CG  . PHE A 1 222 ? -15.803 1.876   -39.009 1.00 50.03  ? 222 PHE A CG  1 
ATOM   1782  C CD1 . PHE A 1 222 ? -16.997 1.253   -38.675 1.00 51.88  ? 222 PHE A CD1 1 
ATOM   1783  C CD2 . PHE A 1 222 ? -15.332 1.763   -40.316 1.00 54.84  ? 222 PHE A CD2 1 
ATOM   1784  C CE1 . PHE A 1 222 ? -17.695 0.516   -39.620 1.00 51.07  ? 222 PHE A CE1 1 
ATOM   1785  C CE2 . PHE A 1 222 ? -16.036 1.028   -41.261 1.00 54.30  ? 222 PHE A CE2 1 
ATOM   1786  C CZ  . PHE A 1 222 ? -17.210 0.406   -40.907 1.00 52.81  ? 222 PHE A CZ  1 
ATOM   1787  N N   . GLU A 1 223 ? -12.399 0.964   -38.030 1.00 38.28  ? 223 GLU A N   1 
ATOM   1788  C CA  . GLU A 1 223 ? -11.611 -0.044  -38.723 1.00 43.45  ? 223 GLU A CA  1 
ATOM   1789  C C   . GLU A 1 223 ? -11.219 -1.161  -37.767 1.00 35.40  ? 223 GLU A C   1 
ATOM   1790  O O   . GLU A 1 223 ? -11.046 -2.283  -38.217 1.00 36.57  ? 223 GLU A O   1 
ATOM   1791  C CB  . GLU A 1 223 ? -10.334 0.508   -39.367 1.00 52.08  ? 223 GLU A CB  1 
ATOM   1792  C CG  . GLU A 1 223 ? -10.543 1.206   -40.707 1.00 60.88  ? 223 GLU A CG  1 
ATOM   1793  C CD  . GLU A 1 223 ? -9.273  1.611   -41.468 1.00 76.86  ? 223 GLU A CD  1 
ATOM   1794  O OE1 . GLU A 1 223 ? -9.425  2.213   -42.569 1.00 82.93  ? 223 GLU A OE1 1 
ATOM   1795  O OE2 . GLU A 1 223 ? -8.112  1.320   -40.993 1.00 53.19  ? 223 GLU A OE2 1 
ATOM   1796  N N   . VAL A 1 224 ? -11.049 -0.849  -36.471 1.00 33.94  ? 224 VAL A N   1 
ATOM   1797  C CA  . VAL A 1 224 ? -10.654 -1.860  -35.497 1.00 34.98  ? 224 VAL A CA  1 
ATOM   1798  C C   . VAL A 1 224 ? -11.845 -2.756  -35.166 1.00 32.62  ? 224 VAL A C   1 
ATOM   1799  O O   . VAL A 1 224 ? -11.666 -3.981  -35.070 1.00 29.86  ? 224 VAL A O   1 
ATOM   1800  C CB  . VAL A 1 224 ? -10.043 -1.228  -34.230 1.00 36.78  ? 224 VAL A CB  1 
ATOM   1801  C CG1 . VAL A 1 224 ? -9.770  -2.264  -33.164 1.00 39.03  ? 224 VAL A CG1 1 
ATOM   1802  C CG2 . VAL A 1 224 ? -8.771  -0.472  -34.545 1.00 35.94  ? 224 VAL A CG2 1 
ATOM   1803  N N   . TYR A 1 225 ? -13.049 -2.152  -35.050 1.00 31.11  ? 225 TYR A N   1 
ATOM   1804  C CA  . TYR A 1 225 ? -14.278 -2.909  -34.894 1.00 31.67  ? 225 TYR A CA  1 
ATOM   1805  C C   . TYR A 1 225 ? -14.472 -3.866  -36.070 1.00 32.51  ? 225 TYR A C   1 
ATOM   1806  O O   . TYR A 1 225 ? -14.842 -5.023  -35.883 1.00 30.68  ? 225 TYR A O   1 
ATOM   1807  C CB  . TYR A 1 225 ? -15.513 -2.015  -34.825 1.00 30.17  ? 225 TYR A CB  1 
ATOM   1808  C CG  . TYR A 1 225 ? -15.691 -1.149  -33.606 1.00 32.61  ? 225 TYR A CG  1 
ATOM   1809  C CD1 . TYR A 1 225 ? -14.890 -1.285  -32.483 1.00 35.70  ? 225 TYR A CD1 1 
ATOM   1810  C CD2 . TYR A 1 225 ? -16.698 -0.187  -33.564 1.00 37.04  ? 225 TYR A CD2 1 
ATOM   1811  C CE1 . TYR A 1 225 ? -15.113 -0.523  -31.345 1.00 34.65  ? 225 TYR A CE1 1 
ATOM   1812  C CE2 . TYR A 1 225 ? -16.907 0.615   -32.443 1.00 35.73  ? 225 TYR A CE2 1 
ATOM   1813  C CZ  . TYR A 1 225 ? -16.099 0.456   -31.334 1.00 38.27  ? 225 TYR A CZ  1 
ATOM   1814  O OH  . TYR A 1 225 ? -16.263 1.198   -30.180 1.00 37.15  ? 225 TYR A OH  1 
ATOM   1815  N N   . GLU A 1 226 ? -14.196 -3.395  -37.287 1.00 30.33  ? 226 GLU A N   1 
ATOM   1816  C CA  . GLU A 1 226 ? -14.315 -4.235  -38.468 1.00 32.21  ? 226 GLU A CA  1 
ATOM   1817  C C   . GLU A 1 226 ? -13.262 -5.355  -38.449 1.00 31.90  ? 226 GLU A C   1 
ATOM   1818  O O   . GLU A 1 226 ? -13.546 -6.499  -38.800 1.00 27.77  ? 226 GLU A O   1 
ATOM   1819  C CB  . GLU A 1 226 ? -14.179 -3.361  -39.715 1.00 31.99  ? 226 GLU A CB  1 
ATOM   1820  C CG  . GLU A 1 226 ? -15.450 -2.554  -39.991 1.00 34.68  ? 226 GLU A CG  1 
ATOM   1821  C CD  . GLU A 1 226 ? -16.565 -3.406  -40.584 1.00 38.28  ? 226 GLU A CD  1 
ATOM   1822  O OE1 . GLU A 1 226 ? -17.471 -3.804  -39.822 1.00 38.30  ? 226 GLU A OE1 1 
ATOM   1823  O OE2 . GLU A 1 226 ? -16.504 -3.696  -41.817 1.00 37.30  ? 226 GLU A OE2 1 
ATOM   1824  N N   . LEU A 1 227 ? -12.026 -5.039  -38.053 1.00 30.36  ? 227 LEU A N   1 
ATOM   1825  C CA  . LEU A 1 227 ? -11.019 -6.078  -37.946 1.00 31.57  ? 227 LEU A CA  1 
ATOM   1826  C C   . LEU A 1 227 ? -11.461 -7.146  -36.939 1.00 31.79  ? 227 LEU A C   1 
ATOM   1827  O O   . LEU A 1 227 ? -11.289 -8.329  -37.204 1.00 33.10  ? 227 LEU A O   1 
ATOM   1828  C CB  . LEU A 1 227 ? -9.689  -5.468  -37.515 1.00 32.95  ? 227 LEU A CB  1 
ATOM   1829  C CG  . LEU A 1 227 ? -8.622  -6.497  -37.149 1.00 34.81  ? 227 LEU A CG  1 
ATOM   1830  C CD1 . LEU A 1 227 ? -8.249  -7.346  -38.359 1.00 33.67  ? 227 LEU A CD1 1 
ATOM   1831  C CD2 . LEU A 1 227 ? -7.388  -5.819  -36.565 1.00 35.78  ? 227 LEU A CD2 1 
ATOM   1832  N N   . PHE A 1 228 ? -12.011 -6.743  -35.780 1.00 27.75  ? 228 PHE A N   1 
ATOM   1833  C CA  . PHE A 1 228 ? -12.388 -7.711  -34.760 1.00 27.44  ? 228 PHE A CA  1 
ATOM   1834  C C   . PHE A 1 228 ? -13.522 -8.594  -35.258 1.00 31.38  ? 228 PHE A C   1 
ATOM   1835  O O   . PHE A 1 228 ? -13.529 -9.785  -34.989 1.00 27.41  ? 228 PHE A O   1 
ATOM   1836  C CB  . PHE A 1 228 ? -12.765 -7.050  -33.422 1.00 27.57  ? 228 PHE A CB  1 
ATOM   1837  C CG  . PHE A 1 228 ? -11.591 -6.786  -32.517 1.00 25.72  ? 228 PHE A CG  1 
ATOM   1838  C CD1 . PHE A 1 228 ? -10.451 -6.160  -32.997 1.00 30.83  ? 228 PHE A CD1 1 
ATOM   1839  C CD2 . PHE A 1 228 ? -11.600 -7.194  -31.190 1.00 30.03  ? 228 PHE A CD2 1 
ATOM   1840  C CE1 . PHE A 1 228 ? -9.337  -5.971  -32.185 1.00 32.48  ? 228 PHE A CE1 1 
ATOM   1841  C CE2 . PHE A 1 228 ? -10.526 -6.906  -30.359 1.00 28.57  ? 228 PHE A CE2 1 
ATOM   1842  C CZ  . PHE A 1 228 ? -9.401  -6.308  -30.852 1.00 29.83  ? 228 PHE A CZ  1 
ATOM   1843  N N   . ARG A 1 229 ? -14.504 -8.005  -35.947 1.00 32.85  ? 229 ARG A N   1 
ATOM   1844  C CA  . ARG A 1 229 ? -15.598 -8.780  -36.516 1.00 29.25  ? 229 ARG A CA  1 
ATOM   1845  C C   . ARG A 1 229 ? -15.048 -9.833  -37.482 1.00 27.90  ? 229 ARG A C   1 
ATOM   1846  O O   . ARG A 1 229 ? -15.421 -11.000 -37.380 1.00 31.49  ? 229 ARG A O   1 
ATOM   1847  C CB  . ARG A 1 229 ? -16.587 -7.876  -37.248 1.00 31.85  ? 229 ARG A CB  1 
ATOM   1848  C CG  . ARG A 1 229 ? -17.393 -6.964  -36.342 1.00 31.59  ? 229 ARG A CG  1 
ATOM   1849  C CD  . ARG A 1 229 ? -17.969 -5.723  -37.037 1.00 32.54  ? 229 ARG A CD  1 
ATOM   1850  N NE  . ARG A 1 229 ? -18.659 -4.864  -36.074 1.00 29.28  ? 229 ARG A NE  1 
ATOM   1851  C CZ  . ARG A 1 229 ? -18.702 -3.536  -36.142 1.00 29.87  ? 229 ARG A CZ  1 
ATOM   1852  N NH1 . ARG A 1 229 ? -18.246 -2.897  -37.196 1.00 34.20  ? 229 ARG A NH1 1 
ATOM   1853  N NH2 . ARG A 1 229 ? -19.255 -2.840  -35.178 1.00 27.76  ? 229 ARG A NH2 1 
ATOM   1854  N N   . LEU A 1 230 ? -14.135 -9.438  -38.373 1.00 31.46  ? 230 LEU A N   1 
ATOM   1855  C CA  . LEU A 1 230 ? -13.546 -10.353 -39.341 1.00 32.28  ? 230 LEU A CA  1 
ATOM   1856  C C   . LEU A 1 230 ? -12.692 -11.412 -38.637 1.00 34.19  ? 230 LEU A C   1 
ATOM   1857  O O   . LEU A 1 230 ? -12.764 -12.600 -38.963 1.00 34.02  ? 230 LEU A O   1 
ATOM   1858  C CB  . LEU A 1 230 ? -12.693 -9.575  -40.352 1.00 32.80  ? 230 LEU A CB  1 
ATOM   1859  C CG  . LEU A 1 230 ? -11.922 -10.433 -41.366 1.00 33.20  ? 230 LEU A CG  1 
ATOM   1860  C CD1 . LEU A 1 230 ? -12.857 -11.330 -42.168 1.00 33.74  ? 230 LEU A CD1 1 
ATOM   1861  C CD2 . LEU A 1 230 ? -11.106 -9.559  -42.304 1.00 36.18  ? 230 LEU A CD2 1 
ATOM   1862  N N   . TYR A 1 231 ? -11.838 -10.971 -37.707 1.00 33.66  ? 231 TYR A N   1 
ATOM   1863  C CA  . TYR A 1 231 ? -10.964 -11.872 -36.967 1.00 32.05  ? 231 TYR A CA  1 
ATOM   1864  C C   . TYR A 1 231 ? -11.799 -12.950 -36.257 1.00 31.18  ? 231 TYR A C   1 
ATOM   1865  O O   . TYR A 1 231 ? -11.475 -14.133 -36.319 1.00 30.75  ? 231 TYR A O   1 
ATOM   1866  C CB  . TYR A 1 231 ? -10.031 -11.071 -36.041 1.00 36.81  ? 231 TYR A CB  1 
ATOM   1867  C CG  . TYR A 1 231 ? -9.140  -11.956 -35.207 1.00 36.84  ? 231 TYR A CG  1 
ATOM   1868  C CD1 . TYR A 1 231 ? -9.690  -12.707 -34.180 1.00 35.78  ? 231 TYR A CD1 1 
ATOM   1869  C CD2 . TYR A 1 231 ? -7.783  -12.097 -35.468 1.00 40.14  ? 231 TYR A CD2 1 
ATOM   1870  C CE1 . TYR A 1 231 ? -8.914  -13.582 -33.445 1.00 42.40  ? 231 TYR A CE1 1 
ATOM   1871  C CE2 . TYR A 1 231 ? -6.995  -12.995 -34.755 1.00 37.89  ? 231 TYR A CE2 1 
ATOM   1872  C CZ  . TYR A 1 231 ? -7.568  -13.734 -33.734 1.00 39.41  ? 231 TYR A CZ  1 
ATOM   1873  O OH  . TYR A 1 231 ? -6.879  -14.617 -32.928 1.00 40.39  ? 231 TYR A OH  1 
ATOM   1874  N N   . MET A 1 232 ? -12.920 -12.559 -35.635 1.00 29.32  ? 232 MET A N   1 
ATOM   1875  C CA  . MET A 1 232 ? -13.740 -13.457 -34.831 1.00 28.70  ? 232 MET A CA  1 
ATOM   1876  C C   . MET A 1 232 ? -14.506 -14.427 -35.728 1.00 28.74  ? 232 MET A C   1 
ATOM   1877  O O   . MET A 1 232 ? -14.697 -15.597 -35.390 1.00 26.91  ? 232 MET A O   1 
ATOM   1878  C CB  . MET A 1 232 ? -14.724 -12.671 -33.963 1.00 29.77  ? 232 MET A CB  1 
ATOM   1879  C CG  . MET A 1 232 ? -14.005 -11.856 -32.869 1.00 35.52  ? 232 MET A CG  1 
ATOM   1880  S SD  . MET A 1 232 ? -13.265 -12.930 -31.620 1.00 39.90  ? 232 MET A SD  1 
ATOM   1881  C CE  . MET A 1 232 ? -11.964 -11.882 -30.962 1.00 41.00  ? 232 MET A CE  1 
ATOM   1882  N N   . PHE A 1 233 ? -14.941 -13.934 -36.888 1.00 30.37  ? 233 PHE A N   1 
ATOM   1883  C CA  . PHE A 1 233 ? -15.500 -14.782 -37.932 1.00 27.51  ? 233 PHE A CA  1 
ATOM   1884  C C   . PHE A 1 233 ? -14.518 -15.865 -38.394 1.00 27.27  ? 233 PHE A C   1 
ATOM   1885  O O   . PHE A 1 233 ? -14.894 -17.038 -38.491 1.00 29.44  ? 233 PHE A O   1 
ATOM   1886  C CB  . PHE A 1 233 ? -15.954 -13.863 -39.065 1.00 29.84  ? 233 PHE A CB  1 
ATOM   1887  C CG  . PHE A 1 233 ? -16.404 -14.560 -40.307 1.00 29.40  ? 233 PHE A CG  1 
ATOM   1888  C CD1 . PHE A 1 233 ? -17.655 -15.126 -40.387 1.00 34.34  ? 233 PHE A CD1 1 
ATOM   1889  C CD2 . PHE A 1 233 ? -15.554 -14.659 -41.394 1.00 32.76  ? 233 PHE A CD2 1 
ATOM   1890  C CE1 . PHE A 1 233 ? -18.065 -15.764 -41.553 1.00 36.10  ? 233 PHE A CE1 1 
ATOM   1891  C CE2 . PHE A 1 233 ? -15.958 -15.305 -42.554 1.00 34.52  ? 233 PHE A CE2 1 
ATOM   1892  C CZ  . PHE A 1 233 ? -17.204 -15.878 -42.616 1.00 33.12  ? 233 PHE A CZ  1 
ATOM   1893  N N   . LEU A 1 234 ? -13.279 -15.489 -38.719 1.00 29.00  ? 234 LEU A N   1 
ATOM   1894  C CA  . LEU A 1 234 ? -12.366 -16.395 -39.410 1.00 31.95  ? 234 LEU A CA  1 
ATOM   1895  C C   . LEU A 1 234 ? -11.863 -17.514 -38.499 1.00 36.02  ? 234 LEU A C   1 
ATOM   1896  O O   . LEU A 1 234 ? -11.577 -18.612 -38.979 1.00 37.24  ? 234 LEU A O   1 
ATOM   1897  C CB  . LEU A 1 234 ? -11.166 -15.606 -39.934 1.00 32.99  ? 234 LEU A CB  1 
ATOM   1898  C CG  . LEU A 1 234 ? -11.424 -14.631 -41.073 1.00 38.66  ? 234 LEU A CG  1 
ATOM   1899  C CD1 . LEU A 1 234 ? -10.116 -13.942 -41.481 1.00 39.55  ? 234 LEU A CD1 1 
ATOM   1900  C CD2 . LEU A 1 234 ? -12.075 -15.322 -42.262 1.00 37.53  ? 234 LEU A CD2 1 
ATOM   1901  N N   . HIS A 1 235 ? -11.695 -17.220 -37.196 1.00 32.58  ? 235 HIS A N   1 
ATOM   1902  C CA  . HIS A 1 235 ? -11.080 -18.153 -36.261 1.00 27.56  ? 235 HIS A CA  1 
ATOM   1903  C C   . HIS A 1 235 ? -12.099 -18.955 -35.479 1.00 28.23  ? 235 HIS A C   1 
ATOM   1904  O O   . HIS A 1 235 ? -11.736 -19.675 -34.551 1.00 31.79  ? 235 HIS A O   1 
ATOM   1905  C CB  . HIS A 1 235 ? -10.178 -17.424 -35.262 1.00 31.55  ? 235 HIS A CB  1 
ATOM   1906  C CG  . HIS A 1 235 ? -8.987  -16.804 -35.884 1.00 33.91  ? 235 HIS A CG  1 
ATOM   1907  N ND1 . HIS A 1 235 ? -9.053  -15.590 -36.535 1.00 35.42  ? 235 HIS A ND1 1 
ATOM   1908  C CD2 . HIS A 1 235 ? -7.704  -17.198 -35.928 1.00 40.20  ? 235 HIS A CD2 1 
ATOM   1909  C CE1 . HIS A 1 235 ? -7.840  -15.308 -37.011 1.00 38.61  ? 235 HIS A CE1 1 
ATOM   1910  N NE2 . HIS A 1 235 ? -7.003  -16.262 -36.637 1.00 40.24  ? 235 HIS A NE2 1 
ATOM   1911  N N   . SER A 1 236 ? -13.355 -18.869 -35.899 1.00 29.44  ? 236 SER A N   1 
ATOM   1912  C CA  . SER A 1 236 ? -14.513 -19.355 -35.164 1.00 29.70  ? 236 SER A CA  1 
ATOM   1913  C C   . SER A 1 236 ? -14.514 -20.879 -35.031 1.00 34.96  ? 236 SER A C   1 
ATOM   1914  O O   . SER A 1 236 ? -14.924 -21.407 -33.993 1.00 32.48  ? 236 SER A O   1 
ATOM   1915  C CB  . SER A 1 236 ? -15.742 -18.896 -35.890 1.00 37.13  ? 236 SER A CB  1 
ATOM   1916  O OG  . SER A 1 236 ? -15.728 -19.418 -37.228 1.00 32.78  ? 236 SER A OG  1 
ATOM   1917  N N   . ASP A 1 237 ? -14.120 -21.601 -36.101 1.00 31.19  ? 237 ASP A N   1 
ATOM   1918  C CA  . ASP A 1 237 ? -14.307 -23.043 -36.133 1.00 31.22  ? 237 ASP A CA  1 
ATOM   1919  C C   . ASP A 1 237 ? -13.420 -23.626 -37.230 1.00 33.60  ? 237 ASP A C   1 
ATOM   1920  O O   . ASP A 1 237 ? -13.208 -22.965 -38.259 1.00 30.89  ? 237 ASP A O   1 
ATOM   1921  C CB  . ASP A 1 237 ? -15.781 -23.396 -36.359 1.00 37.50  ? 237 ASP A CB  1 
ATOM   1922  C CG  . ASP A 1 237 ? -16.175 -24.806 -35.939 1.00 46.92  ? 237 ASP A CG  1 
ATOM   1923  O OD1 . ASP A 1 237 ? -15.755 -25.248 -34.836 1.00 49.09  ? 237 ASP A OD1 1 
ATOM   1924  O OD2 . ASP A 1 237 ? -16.951 -25.450 -36.688 1.00 52.70  ? 237 ASP A OD2 1 
ATOM   1925  N N   . HIS A 1 238 ? -12.856 -24.823 -36.985 1.00 33.23  ? 238 HIS A N   1 
ATOM   1926  C CA  . HIS A 1 238 ? -12.037 -25.513 -37.988 1.00 34.25  ? 238 HIS A CA  1 
ATOM   1927  C C   . HIS A 1 238 ? -12.073 -27.031 -37.783 1.00 31.70  ? 238 HIS A C   1 
ATOM   1928  O O   . HIS A 1 238 ? -11.054 -27.639 -37.460 1.00 33.45  ? 238 HIS A O   1 
ATOM   1929  C CB  . HIS A 1 238 ? -10.602 -25.015 -37.915 1.00 38.08  ? 238 HIS A CB  1 
ATOM   1930  C CG  . HIS A 1 238 ? -9.841  -25.052 -39.207 1.00 38.88  ? 238 HIS A CG  1 
ATOM   1931  N ND1 . HIS A 1 238 ? -8.701  -25.792 -39.396 1.00 36.49  ? 238 HIS A ND1 1 
ATOM   1932  C CD2 . HIS A 1 238 ? -10.031 -24.372 -40.343 1.00 40.24  ? 238 HIS A CD2 1 
ATOM   1933  C CE1 . HIS A 1 238 ? -8.229  -25.558 -40.609 1.00 43.96  ? 238 HIS A CE1 1 
ATOM   1934  N NE2 . HIS A 1 238 ? -9.030  -24.697 -41.206 1.00 38.13  ? 238 HIS A NE2 1 
ATOM   1935  N N   . GLU A 1 239 ? -13.268 -27.616 -37.922 1.00 32.88  ? 239 GLU A N   1 
ATOM   1936  C CA  . GLU A 1 239 ? -13.509 -29.042 -37.723 1.00 34.33  ? 239 GLU A CA  1 
ATOM   1937  C C   . GLU A 1 239 ? -13.358 -29.392 -36.253 1.00 36.77  ? 239 GLU A C   1 
ATOM   1938  O O   . GLU A 1 239 ? -13.191 -28.528 -35.389 1.00 37.90  ? 239 GLU A O   1 
ATOM   1939  C CB  . GLU A 1 239 ? -12.535 -29.927 -38.515 1.00 39.62  ? 239 GLU A CB  1 
ATOM   1940  C CG  . GLU A 1 239 ? -12.947 -30.156 -39.923 1.00 52.61  ? 239 GLU A CG  1 
ATOM   1941  C CD  . GLU A 1 239 ? -12.169 -31.270 -40.620 1.00 50.44  ? 239 GLU A CD  1 
ATOM   1942  O OE1 . GLU A 1 239 ? -12.509 -31.507 -41.776 1.00 54.20  ? 239 GLU A OE1 1 
ATOM   1943  O OE2 . GLU A 1 239 ? -11.258 -31.908 -39.992 1.00 45.73  ? 239 GLU A OE2 1 
ATOM   1944  N N   . GLY A 1 240 ? -13.456 -30.693 -35.982 1.00 35.36  ? 240 GLY A N   1 
ATOM   1945  C CA  . GLY A 1 240 ? -13.543 -31.165 -34.621 1.00 33.46  ? 240 GLY A CA  1 
ATOM   1946  C C   . GLY A 1 240 ? -12.192 -31.670 -34.127 1.00 30.83  ? 240 GLY A C   1 
ATOM   1947  O O   . GLY A 1 240 ? -12.043 -31.914 -32.932 1.00 34.10  ? 240 GLY A O   1 
ATOM   1948  N N   . GLY A 1 241 ? -11.215 -31.801 -35.028 1.00 28.33  ? 241 GLY A N   1 
ATOM   1949  C CA  . GLY A 1 241 ? -10.015 -32.576 -34.718 1.00 29.40  ? 241 GLY A CA  1 
ATOM   1950  C C   . GLY A 1 241 ? -8.827  -31.787 -34.147 1.00 32.07  ? 241 GLY A C   1 
ATOM   1951  O O   . GLY A 1 241 ? -7.864  -32.377 -33.639 1.00 36.53  ? 241 GLY A O   1 
ATOM   1952  N N   . ASN A 1 242 ? -8.848  -30.453 -34.247 1.00 33.88  ? 242 ASN A N   1 
ATOM   1953  C CA  . ASN A 1 242 ? -7.776  -29.651 -33.687 1.00 33.74  ? 242 ASN A CA  1 
ATOM   1954  C C   . ASN A 1 242 ? -7.820  -29.792 -32.153 1.00 32.91  ? 242 ASN A C   1 
ATOM   1955  O O   . ASN A 1 242 ? -8.847  -30.120 -31.552 1.00 30.95  ? 242 ASN A O   1 
ATOM   1956  C CB  . ASN A 1 242 ? -7.868  -28.213 -34.204 1.00 32.75  ? 242 ASN A CB  1 
ATOM   1957  C CG  . ASN A 1 242 ? -9.093  -27.469 -33.704 1.00 33.55  ? 242 ASN A CG  1 
ATOM   1958  O OD1 . ASN A 1 242 ? -9.195  -27.164 -32.520 1.00 33.09  ? 242 ASN A OD1 1 
ATOM   1959  N ND2 . ASN A 1 242 ? -10.075 -27.255 -34.565 1.00 36.39  ? 242 ASN A ND2 1 
ATOM   1960  N N   . VAL A 1 243 ? -6.702  -29.544 -31.484 1.00 30.23  ? 243 VAL A N   1 
ATOM   1961  C CA  . VAL A 1 243 ? -6.607  -29.852 -30.064 1.00 32.43  ? 243 VAL A CA  1 
ATOM   1962  C C   . VAL A 1 243 ? -7.675  -29.137 -29.231 1.00 31.18  ? 243 VAL A C   1 
ATOM   1963  O O   . VAL A 1 243 ? -8.276  -29.768 -28.376 1.00 33.29  ? 243 VAL A O   1 
ATOM   1964  C CB  . VAL A 1 243 ? -5.191  -29.555 -29.564 1.00 35.97  ? 243 VAL A CB  1 
ATOM   1965  C CG1 . VAL A 1 243 ? -5.127  -29.481 -28.043 1.00 36.20  ? 243 VAL A CG1 1 
ATOM   1966  C CG2 . VAL A 1 243 ? -4.249  -30.608 -30.102 1.00 33.58  ? 243 VAL A CG2 1 
ATOM   1967  N N   . SER A 1 244 ? -7.975  -27.854 -29.490 1.00 31.57  ? 244 SER A N   1 
ATOM   1968  C CA  . SER A 1 244 ? -8.945  -27.177 -28.643 1.00 33.72  ? 244 SER A CA  1 
ATOM   1969  C C   . SER A 1 244 ? -10.370 -27.706 -28.868 1.00 33.02  ? 244 SER A C   1 
ATOM   1970  O O   . SER A 1 244 ? -11.102 -27.958 -27.913 1.00 31.04  ? 244 SER A O   1 
ATOM   1971  C CB  . SER A 1 244 ? -8.844  -25.660 -28.739 1.00 33.40  ? 244 SER A CB  1 
ATOM   1972  O OG  . SER A 1 244 ? -8.982  -25.173 -30.068 1.00 38.24  ? 244 SER A OG  1 
ATOM   1973  N N   . ALA A 1 245 ? -10.800 -27.851 -30.121 1.00 29.75  ? 245 ALA A N   1 
ATOM   1974  C CA  . ALA A 1 245 ? -12.144 -28.366 -30.403 1.00 29.26  ? 245 ALA A CA  1 
ATOM   1975  C C   . ALA A 1 245 ? -12.302 -29.780 -29.844 1.00 26.09  ? 245 ALA A C   1 
ATOM   1976  O O   . ALA A 1 245 ? -13.334 -30.154 -29.320 1.00 27.78  ? 245 ALA A O   1 
ATOM   1977  C CB  . ALA A 1 245 ? -12.385 -28.356 -31.914 1.00 30.84  ? 245 ALA A CB  1 
ATOM   1978  N N   . HIS A 1 246 ? -11.258 -30.586 -29.987 1.00 29.25  ? 246 HIS A N   1 
ATOM   1979  C CA  . HIS A 1 246 ? -11.299 -31.975 -29.594 1.00 26.60  ? 246 HIS A CA  1 
ATOM   1980  C C   . HIS A 1 246 ? -11.312 -32.070 -28.072 1.00 27.37  ? 246 HIS A C   1 
ATOM   1981  O O   . HIS A 1 246 ? -12.051 -32.865 -27.491 1.00 25.45  ? 246 HIS A O   1 
ATOM   1982  C CB  . HIS A 1 246 ? -10.082 -32.674 -30.192 1.00 27.99  ? 246 HIS A CB  1 
ATOM   1983  C CG  . HIS A 1 246 ? -10.041 -34.147 -29.906 1.00 29.09  ? 246 HIS A CG  1 
ATOM   1984  N ND1 . HIS A 1 246 ? -8.929  -34.935 -30.120 1.00 31.83  ? 246 HIS A ND1 1 
ATOM   1985  C CD2 . HIS A 1 246 ? -10.988 -34.961 -29.436 1.00 32.07  ? 246 HIS A CD2 1 
ATOM   1986  C CE1 . HIS A 1 246 ? -9.203  -36.171 -29.736 1.00 29.59  ? 246 HIS A CE1 1 
ATOM   1987  N NE2 . HIS A 1 246 ? -10.441 -36.203 -29.323 1.00 28.04  ? 246 HIS A NE2 1 
ATOM   1988  N N   . THR A 1 247 ? -10.471 -31.274 -27.406 1.00 23.98  ? 247 THR A N   1 
ATOM   1989  C CA  . THR A 1 247 ? -10.522 -31.257 -25.947 1.00 24.00  ? 247 THR A CA  1 
ATOM   1990  C C   . THR A 1 247 ? -11.916 -30.864 -25.466 1.00 26.16  ? 247 THR A C   1 
ATOM   1991  O O   . THR A 1 247 ? -12.427 -31.475 -24.536 1.00 27.60  ? 247 THR A O   1 
ATOM   1992  C CB  . THR A 1 247 ? -9.474  -30.299 -25.358 1.00 25.89  ? 247 THR A CB  1 
ATOM   1993  O OG1 . THR A 1 247 ? -8.209  -30.716 -25.877 1.00 27.56  ? 247 THR A OG1 1 
ATOM   1994  C CG2 . THR A 1 247 ? -9.442  -30.279 -23.838 1.00 24.61  ? 247 THR A CG2 1 
ATOM   1995  N N   . ASN A 1 248 ? -12.540 -29.843 -26.077 1.00 26.57  ? 248 ASN A N   1 
ATOM   1996  C CA  . ASN A 1 248 ? -13.895 -29.463 -25.698 1.00 29.17  ? 248 ASN A CA  1 
ATOM   1997  C C   . ASN A 1 248 ? -14.862 -30.660 -25.834 1.00 29.71  ? 248 ASN A C   1 
ATOM   1998  O O   . ASN A 1 248 ? -15.670 -30.934 -24.936 1.00 26.80  ? 248 ASN A O   1 
ATOM   1999  C CB  . ASN A 1 248 ? -14.318 -28.260 -26.551 1.00 30.20  ? 248 ASN A CB  1 
ATOM   2000  C CG  . ASN A 1 248 ? -15.746 -27.816 -26.337 1.00 31.57  ? 248 ASN A CG  1 
ATOM   2001  O OD1 . ASN A 1 248 ? -16.587 -27.862 -27.257 1.00 34.56  ? 248 ASN A OD1 1 
ATOM   2002  N ND2 . ASN A 1 248 ? -16.017 -27.423 -25.111 1.00 30.45  ? 248 ASN A ND2 1 
ATOM   2003  N N   . LEU A 1 249 ? -14.816 -31.375 -26.972 1.00 29.99  ? 249 LEU A N   1 
ATOM   2004  C CA  . LEU A 1 249 ? -15.729 -32.496 -27.199 1.00 28.74  ? 249 LEU A CA  1 
ATOM   2005  C C   . LEU A 1 249 ? -15.479 -33.636 -26.209 1.00 29.24  ? 249 LEU A C   1 
ATOM   2006  O O   . LEU A 1 249 ? -16.416 -34.265 -25.731 1.00 30.91  ? 249 LEU A O   1 
ATOM   2007  C CB  . LEU A 1 249 ? -15.552 -33.002 -28.639 1.00 32.03  ? 249 LEU A CB  1 
ATOM   2008  C CG  . LEU A 1 249 ? -16.028 -32.049 -29.741 1.00 37.79  ? 249 LEU A CG  1 
ATOM   2009  C CD1 . LEU A 1 249 ? -15.614 -32.549 -31.131 1.00 41.04  ? 249 LEU A CD1 1 
ATOM   2010  C CD2 . LEU A 1 249 ? -17.540 -31.858 -29.674 1.00 43.57  ? 249 LEU A CD2 1 
ATOM   2011  N N   . LEU A 1 250 ? -14.206 -33.918 -25.919 1.00 27.45  ? 250 LEU A N   1 
ATOM   2012  C CA  . LEU A 1 250 ? -13.840 -35.017 -25.051 1.00 28.21  ? 250 LEU A CA  1 
ATOM   2013  C C   . LEU A 1 250 ? -14.380 -34.793 -23.639 1.00 28.17  ? 250 LEU A C   1 
ATOM   2014  O O   . LEU A 1 250 ? -15.037 -35.656 -23.042 1.00 25.36  ? 250 LEU A O   1 
ATOM   2015  C CB  . LEU A 1 250 ? -12.313 -35.130 -25.130 1.00 28.71  ? 250 LEU A CB  1 
ATOM   2016  C CG  . LEU A 1 250 ? -11.636 -36.028 -24.110 1.00 31.15  ? 250 LEU A CG  1 
ATOM   2017  C CD1 . LEU A 1 250 ? -12.238 -37.425 -24.142 1.00 33.22  ? 250 LEU A CD1 1 
ATOM   2018  C CD2 . LEU A 1 250 ? -10.143 -36.083 -24.388 1.00 33.11  ? 250 LEU A CD2 1 
ATOM   2019  N N   . VAL A 1 251 ? -14.186 -33.575 -23.116 1.00 27.59  ? 251 VAL A N   1 
ATOM   2020  C CA  . VAL A 1 251 ? -14.637 -33.295 -21.763 1.00 25.84  ? 251 VAL A CA  1 
ATOM   2021  C C   . VAL A 1 251 ? -16.165 -33.199 -21.730 1.00 25.58  ? 251 VAL A C   1 
ATOM   2022  O O   . VAL A 1 251 ? -16.812 -33.669 -20.811 1.00 23.68  ? 251 VAL A O   1 
ATOM   2023  C CB  . VAL A 1 251 ? -13.929 -32.023 -21.282 1.00 23.21  ? 251 VAL A CB  1 
ATOM   2024  C CG1 . VAL A 1 251 ? -14.537 -31.507 -20.005 1.00 26.32  ? 251 VAL A CG1 1 
ATOM   2025  C CG2 . VAL A 1 251 ? -12.433 -32.251 -21.135 1.00 27.01  ? 251 VAL A CG2 1 
ATOM   2026  N N   . ASN A 1 252 ? -16.756 -32.592 -22.762 1.00 26.20  ? 252 ASN A N   1 
ATOM   2027  C CA  . ASN A 1 252 ? -18.213 -32.522 -22.912 1.00 28.52  ? 252 ASN A CA  1 
ATOM   2028  C C   . ASN A 1 252 ? -18.844 -33.917 -22.969 1.00 28.93  ? 252 ASN A C   1 
ATOM   2029  O O   . ASN A 1 252 ? -19.926 -34.098 -22.425 1.00 29.14  ? 252 ASN A O   1 
ATOM   2030  C CB  . ASN A 1 252 ? -18.577 -31.711 -24.154 1.00 28.06  ? 252 ASN A CB  1 
ATOM   2031  C CG  . ASN A 1 252 ? -20.029 -31.839 -24.509 1.00 33.70  ? 252 ASN A CG  1 
ATOM   2032  O OD1 . ASN A 1 252 ? -20.411 -32.794 -25.202 1.00 34.59  ? 252 ASN A OD1 1 
ATOM   2033  N ND2 . ASN A 1 252 ? -20.808 -30.863 -24.058 1.00 30.70  ? 252 ASN A ND2 1 
ATOM   2034  N N   . SER A 1 253 ? -18.113 -34.900 -23.537 1.00 28.30  ? 253 SER A N   1 
ATOM   2035  C CA  . SER A 1 253 ? -18.572 -36.283 -23.673 1.00 31.13  ? 253 SER A CA  1 
ATOM   2036  C C   . SER A 1 253 ? -18.859 -36.968 -22.329 1.00 33.75  ? 253 SER A C   1 
ATOM   2037  O O   . SER A 1 253 ? -19.705 -37.889 -22.230 1.00 28.96  ? 253 SER A O   1 
ATOM   2038  C CB  . SER A 1 253 ? -17.620 -37.101 -24.557 1.00 29.59  ? 253 SER A CB  1 
ATOM   2039  O OG  . SER A 1 253 ? -16.502 -37.658 -23.845 1.00 30.55  ? 253 SER A OG  1 
ATOM   2040  N N   . ALA A 1 254 ? -18.217 -36.489 -21.254 1.00 32.29  ? 254 ALA A N   1 
ATOM   2041  C CA  . ALA A 1 254 ? -18.470 -37.028 -19.927 1.00 27.29  ? 254 ALA A CA  1 
ATOM   2042  C C   . ALA A 1 254 ? -19.592 -36.282 -19.224 1.00 26.84  ? 254 ALA A C   1 
ATOM   2043  O O   . ALA A 1 254 ? -19.784 -36.498 -18.036 1.00 27.38  ? 254 ALA A O   1 
ATOM   2044  C CB  . ALA A 1 254 ? -17.223 -37.009 -19.078 1.00 28.98  ? 254 ALA A CB  1 
ATOM   2045  N N   . TYR A 1 255 ? -20.296 -35.397 -19.938 1.00 28.51  ? 255 TYR A N   1 
ATOM   2046  C CA  . TYR A 1 255 ? -21.351 -34.544 -19.392 1.00 29.28  ? 255 TYR A CA  1 
ATOM   2047  C C   . TYR A 1 255 ? -20.798 -33.426 -18.505 1.00 30.21  ? 255 TYR A C   1 
ATOM   2048  O O   . TYR A 1 255 ? -21.506 -32.915 -17.651 1.00 32.11  ? 255 TYR A O   1 
ATOM   2049  C CB  . TYR A 1 255 ? -22.418 -35.306 -18.603 1.00 34.55  ? 255 TYR A CB  1 
ATOM   2050  C CG  . TYR A 1 255 ? -23.376 -36.152 -19.410 1.00 36.91  ? 255 TYR A CG  1 
ATOM   2051  C CD1 . TYR A 1 255 ? -23.359 -36.156 -20.802 1.00 39.55  ? 255 TYR A CD1 1 
ATOM   2052  C CD2 . TYR A 1 255 ? -24.283 -36.982 -18.765 1.00 36.91  ? 255 TYR A CD2 1 
ATOM   2053  C CE1 . TYR A 1 255 ? -24.237 -36.938 -21.530 1.00 38.79  ? 255 TYR A CE1 1 
ATOM   2054  C CE2 . TYR A 1 255 ? -25.165 -37.775 -19.481 1.00 42.75  ? 255 TYR A CE2 1 
ATOM   2055  C CZ  . TYR A 1 255 ? -25.135 -37.753 -20.865 1.00 45.45  ? 255 TYR A CZ  1 
ATOM   2056  O OH  . TYR A 1 255 ? -26.004 -38.517 -21.599 1.00 46.44  ? 255 TYR A OH  1 
ATOM   2057  N N   . SER A 1 256 ? -19.543 -33.027 -18.710 1.00 31.76  ? 256 SER A N   1 
ATOM   2058  C CA  . SER A 1 256 ? -19.024 -31.846 -18.037 1.00 30.08  ? 256 SER A CA  1 
ATOM   2059  C C   . SER A 1 256 ? -19.563 -30.636 -18.803 1.00 32.68  ? 256 SER A C   1 
ATOM   2060  O O   . SER A 1 256 ? -19.549 -30.630 -20.039 1.00 29.13  ? 256 SER A O   1 
ATOM   2061  C CB  . SER A 1 256 ? -17.528 -31.853 -18.015 1.00 28.80  ? 256 SER A CB  1 
ATOM   2062  O OG  . SER A 1 256 ? -17.021 -32.774 -17.072 1.00 32.43  ? 256 SER A OG  1 
ATOM   2063  N N   . ASP A 1 257 ? -19.994 -29.614 -18.071 1.00 27.48  ? 257 ASP A N   1 
ATOM   2064  C CA  . ASP A 1 257 ? -20.606 -28.426 -18.664 1.00 27.36  ? 257 ASP A CA  1 
ATOM   2065  C C   . ASP A 1 257 ? -19.596 -27.584 -19.456 1.00 27.39  ? 257 ASP A C   1 
ATOM   2066  O O   . ASP A 1 257 ? -18.404 -27.895 -19.476 1.00 26.84  ? 257 ASP A O   1 
ATOM   2067  C CB  . ASP A 1 257 ? -21.310 -27.643 -17.573 1.00 31.40  ? 257 ASP A CB  1 
ATOM   2068  C CG  . ASP A 1 257 ? -20.331 -27.074 -16.555 1.00 36.02  ? 257 ASP A CG  1 
ATOM   2069  O OD1 . ASP A 1 257 ? -19.436 -26.242 -16.973 1.00 32.42  ? 257 ASP A OD1 1 
ATOM   2070  O OD2 . ASP A 1 257 ? -20.449 -27.503 -15.389 1.00 33.15  ? 257 ASP A OD2 1 
ATOM   2071  N N   . ILE A 1 258 ? -20.089 -26.537 -20.142 1.00 25.04  ? 258 ILE A N   1 
ATOM   2072  C CA  . ILE A 1 258 ? -19.313 -25.849 -21.164 1.00 27.09  ? 258 ILE A CA  1 
ATOM   2073  C C   . ILE A 1 258 ? -18.203 -25.039 -20.497 1.00 23.65  ? 258 ILE A C   1 
ATOM   2074  O O   . ILE A 1 258 ? -17.197 -24.773 -21.120 1.00 22.68  ? 258 ILE A O   1 
ATOM   2075  C CB  . ILE A 1 258 ? -20.200 -24.967 -22.066 1.00 26.06  ? 258 ILE A CB  1 
ATOM   2076  C CG1 . ILE A 1 258 ? -19.453 -24.460 -23.293 1.00 28.00  ? 258 ILE A CG1 1 
ATOM   2077  C CG2 . ILE A 1 258 ? -20.792 -23.814 -21.270 1.00 24.72  ? 258 ILE A CG2 1 
ATOM   2078  C CD1 . ILE A 1 258 ? -19.211 -25.502 -24.373 1.00 32.32  ? 258 ILE A CD1 1 
ATOM   2079  N N   . TYR A 1 259 ? -18.400 -24.646 -19.242 1.00 25.29  ? 259 TYR A N   1 
ATOM   2080  C CA  . TYR A 1 259 ? -17.371 -23.909 -18.542 1.00 24.46  ? 259 TYR A CA  1 
ATOM   2081  C C   . TYR A 1 259 ? -16.174 -24.809 -18.294 1.00 24.92  ? 259 TYR A C   1 
ATOM   2082  O O   . TYR A 1 259 ? -15.032 -24.380 -18.438 1.00 27.49  ? 259 TYR A O   1 
ATOM   2083  C CB  . TYR A 1 259 ? -17.894 -23.327 -17.238 1.00 24.15  ? 259 TYR A CB  1 
ATOM   2084  C CG  . TYR A 1 259 ? -18.998 -22.333 -17.433 1.00 24.13  ? 259 TYR A CG  1 
ATOM   2085  C CD1 . TYR A 1 259 ? -18.724 -21.028 -17.787 1.00 24.79  ? 259 TYR A CD1 1 
ATOM   2086  C CD2 . TYR A 1 259 ? -20.313 -22.687 -17.202 1.00 26.12  ? 259 TYR A CD2 1 
ATOM   2087  C CE1 . TYR A 1 259 ? -19.742 -20.103 -17.918 1.00 26.59  ? 259 TYR A CE1 1 
ATOM   2088  C CE2 . TYR A 1 259 ? -21.342 -21.769 -17.327 1.00 29.36  ? 259 TYR A CE2 1 
ATOM   2089  C CZ  . TYR A 1 259 ? -21.062 -20.479 -17.714 1.00 28.38  ? 259 TYR A CZ  1 
ATOM   2090  O OH  . TYR A 1 259 ? -22.084 -19.566 -17.863 1.00 28.43  ? 259 TYR A OH  1 
ATOM   2091  N N   . ARG A 1 260 ? -16.441 -26.054 -17.918 1.00 25.25  ? 260 ARG A N   1 
ATOM   2092  C CA  . ARG A 1 260 ? -15.371 -27.019 -17.766 1.00 24.29  ? 260 ARG A CA  1 
ATOM   2093  C C   . ARG A 1 260 ? -14.775 -27.449 -19.102 1.00 27.09  ? 260 ARG A C   1 
ATOM   2094  O O   . ARG A 1 260 ? -13.558 -27.581 -19.221 1.00 23.08  ? 260 ARG A O   1 
ATOM   2095  C CB  . ARG A 1 260 ? -15.908 -28.226 -17.028 1.00 26.83  ? 260 ARG A CB  1 
ATOM   2096  C CG  . ARG A 1 260 ? -16.029 -27.987 -15.537 1.00 27.29  ? 260 ARG A CG  1 
ATOM   2097  C CD  . ARG A 1 260 ? -16.643 -29.167 -14.853 1.00 26.37  ? 260 ARG A CD  1 
ATOM   2098  N NE  . ARG A 1 260 ? -16.588 -29.038 -13.417 1.00 31.48  ? 260 ARG A NE  1 
ATOM   2099  C CZ  . ARG A 1 260 ? -17.399 -29.642 -12.568 1.00 28.31  ? 260 ARG A CZ  1 
ATOM   2100  N NH1 . ARG A 1 260 ? -18.437 -30.317 -13.011 1.00 30.21  ? 260 ARG A NH1 1 
ATOM   2101  N NH2 . ARG A 1 260 ? -17.201 -29.532 -11.269 1.00 27.42  ? 260 ARG A NH2 1 
ATOM   2102  N N   . SER A 1 261 ? -15.608 -27.693 -20.119 1.00 24.61  ? 261 SER A N   1 
ATOM   2103  C CA  . SER A 1 261 ? -15.052 -28.232 -21.355 1.00 25.24  ? 261 SER A CA  1 
ATOM   2104  C C   . SER A 1 261 ? -14.290 -27.144 -22.101 1.00 26.71  ? 261 SER A C   1 
ATOM   2105  O O   . SER A 1 261 ? -13.238 -27.402 -22.712 1.00 23.76  ? 261 SER A O   1 
ATOM   2106  C CB  . SER A 1 261 ? -16.114 -28.882 -22.244 1.00 27.01  ? 261 SER A CB  1 
ATOM   2107  O OG  . SER A 1 261 ? -17.035 -27.934 -22.779 1.00 27.71  ? 261 SER A OG  1 
ATOM   2108  N N   . PHE A 1 262 ? -14.808 -25.911 -22.043 1.00 23.87  ? 262 PHE A N   1 
ATOM   2109  C CA  . PHE A 1 262 ? -14.171 -24.845 -22.795 1.00 23.68  ? 262 PHE A CA  1 
ATOM   2110  C C   . PHE A 1 262 ? -12.934 -24.335 -22.065 1.00 21.62  ? 262 PHE A C   1 
ATOM   2111  O O   . PHE A 1 262 ? -11.934 -24.036 -22.701 1.00 23.62  ? 262 PHE A O   1 
ATOM   2112  C CB  . PHE A 1 262 ? -15.147 -23.720 -23.131 1.00 25.36  ? 262 PHE A CB  1 
ATOM   2113  C CG  . PHE A 1 262 ? -14.518 -22.713 -24.052 1.00 25.67  ? 262 PHE A CG  1 
ATOM   2114  C CD1 . PHE A 1 262 ? -14.302 -23.030 -25.382 1.00 28.11  ? 262 PHE A CD1 1 
ATOM   2115  C CD2 . PHE A 1 262 ? -14.123 -21.469 -23.579 1.00 26.80  ? 262 PHE A CD2 1 
ATOM   2116  C CE1 . PHE A 1 262 ? -13.661 -22.128 -26.226 1.00 30.18  ? 262 PHE A CE1 1 
ATOM   2117  C CE2 . PHE A 1 262 ? -13.496 -20.562 -24.416 1.00 28.36  ? 262 PHE A CE2 1 
ATOM   2118  C CZ  . PHE A 1 262 ? -13.280 -20.889 -25.751 1.00 28.41  ? 262 PHE A CZ  1 
ATOM   2119  N N   . SER A 1 263 ? -12.928 -24.330 -20.729 1.00 23.12  ? 263 SER A N   1 
ATOM   2120  C CA  . SER A 1 263 ? -11.703 -23.982 -20.030 1.00 23.04  ? 263 SER A CA  1 
ATOM   2121  C C   . SER A 1 263 ? -10.626 -25.048 -20.275 1.00 25.34  ? 263 SER A C   1 
ATOM   2122  O O   . SER A 1 263 ? -9.458  -24.689 -20.479 1.00 23.05  ? 263 SER A O   1 
ATOM   2123  C CB  . SER A 1 263 ? -11.937 -23.713 -18.600 1.00 22.35  ? 263 SER A CB  1 
ATOM   2124  O OG  . SER A 1 263 ? -12.292 -24.896 -17.898 1.00 23.00  ? 263 SER A OG  1 
ATOM   2125  N N   . ALA A 1 264 ? -11.015 -26.334 -20.341 1.00 24.78  ? 264 ALA A N   1 
ATOM   2126  C CA  . ALA A 1 264 ? -10.078 -27.378 -20.740 1.00 23.51  ? 264 ALA A CA  1 
ATOM   2127  C C   . ALA A 1 264 ? -9.529  -27.120 -22.150 1.00 25.98  ? 264 ALA A C   1 
ATOM   2128  O O   . ALA A 1 264 ? -8.316  -27.207 -22.374 1.00 24.90  ? 264 ALA A O   1 
ATOM   2129  C CB  . ALA A 1 264 ? -10.714 -28.739 -20.574 1.00 24.89  ? 264 ALA A CB  1 
ATOM   2130  N N   . ALA A 1 265 ? -10.393 -26.735 -23.100 1.00 24.80  ? 265 ALA A N   1 
ATOM   2131  C CA  . ALA A 1 265 ? -9.960  -26.457 -24.462 1.00 27.13  ? 265 ALA A CA  1 
ATOM   2132  C C   . ALA A 1 265 ? -8.942  -25.313 -24.492 1.00 26.54  ? 265 ALA A C   1 
ATOM   2133  O O   . ALA A 1 265 ? -8.015  -25.304 -25.297 1.00 24.14  ? 265 ALA A O   1 
ATOM   2134  C CB  . ALA A 1 265 ? -11.145 -26.131 -25.352 1.00 27.26  ? 265 ALA A CB  1 
ATOM   2135  N N   . MET A 1 266 ? -9.117  -24.331 -23.613 1.00 23.68  ? 266 MET A N   1 
ATOM   2136  C CA  . MET A 1 266 ? -8.231  -23.189 -23.615 1.00 23.05  ? 266 MET A CA  1 
ATOM   2137  C C   . MET A 1 266 ? -6.849  -23.578 -23.098 1.00 23.10  ? 266 MET A C   1 
ATOM   2138  O O   . MET A 1 266 ? -5.871  -22.995 -23.530 1.00 27.55  ? 266 MET A O   1 
ATOM   2139  C CB  . MET A 1 266 ? -8.837  -22.036 -22.800 1.00 24.33  ? 266 MET A CB  1 
ATOM   2140  C CG  . MET A 1 266 ? -10.051 -21.405 -23.505 1.00 24.02  ? 266 MET A CG  1 
ATOM   2141  S SD  . MET A 1 266 ? -9.744  -20.763 -25.166 1.00 27.80  ? 266 MET A SD  1 
ATOM   2142  C CE  . MET A 1 266 ? -10.171 -22.164 -26.205 1.00 29.12  ? 266 MET A CE  1 
ATOM   2143  N N   . ASN A 1 267 ? -6.765  -24.533 -22.166 1.00 23.64  ? 267 ASN A N   1 
ATOM   2144  C CA  . ASN A 1 267 ? -5.482  -25.047 -21.715 1.00 25.08  ? 267 ASN A CA  1 
ATOM   2145  C C   . ASN A 1 267 ? -4.727  -25.748 -22.855 1.00 27.09  ? 267 ASN A C   1 
ATOM   2146  O O   . ASN A 1 267 ? -3.503  -25.710 -22.877 1.00 27.95  ? 267 ASN A O   1 
ATOM   2147  C CB  . ASN A 1 267 ? -5.661  -26.025 -20.560 1.00 25.83  ? 267 ASN A CB  1 
ATOM   2148  C CG  . ASN A 1 267 ? -6.042  -25.324 -19.280 1.00 28.30  ? 267 ASN A CG  1 
ATOM   2149  O OD1 . ASN A 1 267 ? -6.068  -24.094 -19.222 1.00 24.80  ? 267 ASN A OD1 1 
ATOM   2150  N ND2 . ASN A 1 267 ? -6.294  -26.109 -18.255 1.00 27.84  ? 267 ASN A ND2 1 
ATOM   2151  N N   . GLY A 1 268 ? -5.468  -26.355 -23.792 1.00 27.70  ? 268 GLY A N   1 
ATOM   2152  C CA  . GLY A 1 268 ? -4.900  -26.923 -25.013 1.00 27.59  ? 268 GLY A CA  1 
ATOM   2153  C C   . GLY A 1 268 ? -4.489  -25.853 -26.016 1.00 26.04  ? 268 GLY A C   1 
ATOM   2154  O O   . GLY A 1 268 ? -3.414  -25.916 -26.580 1.00 26.95  ? 268 GLY A O   1 
ATOM   2155  N N   . LEU A 1 269 ? -5.352  -24.851 -26.222 1.00 25.95  ? 269 LEU A N   1 
ATOM   2156  C CA  . LEU A 1 269 ? -5.047  -23.762 -27.125 1.00 24.85  ? 269 LEU A CA  1 
ATOM   2157  C C   . LEU A 1 269 ? -3.824  -23.002 -26.628 1.00 25.94  ? 269 LEU A C   1 
ATOM   2158  O O   . LEU A 1 269 ? -3.091  -22.459 -27.446 1.00 25.71  ? 269 LEU A O   1 
ATOM   2159  C CB  . LEU A 1 269 ? -6.259  -22.849 -27.275 1.00 28.84  ? 269 LEU A CB  1 
ATOM   2160  C CG  . LEU A 1 269 ? -6.098  -21.755 -28.318 1.00 35.25  ? 269 LEU A CG  1 
ATOM   2161  C CD1 . LEU A 1 269 ? -5.946  -22.399 -29.700 1.00 39.09  ? 269 LEU A CD1 1 
ATOM   2162  C CD2 . LEU A 1 269 ? -7.259  -20.774 -28.307 1.00 33.05  ? 269 LEU A CD2 1 
ATOM   2163  N N   . ALA A 1 270 ? -3.583  -22.997 -25.308 1.00 29.41  ? 270 ALA A N   1 
ATOM   2164  C CA  . ALA A 1 270 ? -2.429  -22.304 -24.758 1.00 31.58  ? 270 ALA A CA  1 
ATOM   2165  C C   . ALA A 1 270 ? -1.123  -22.993 -25.153 1.00 31.65  ? 270 ALA A C   1 
ATOM   2166  O O   . ALA A 1 270 ? -0.047  -22.439 -24.963 1.00 27.94  ? 270 ALA A O   1 
ATOM   2167  C CB  . ALA A 1 270 ? -2.528  -22.244 -23.251 1.00 29.85  ? 270 ALA A CB  1 
ATOM   2168  N N   . GLY A 1 271 ? -1.187  -24.253 -25.585 1.00 30.06  ? 271 GLY A N   1 
ATOM   2169  C CA  . GLY A 1 271 ? 0.041   -24.938 -25.945 1.00 28.95  ? 271 GLY A CA  1 
ATOM   2170  C C   . GLY A 1 271 ? 0.736   -24.264 -27.133 1.00 30.16  ? 271 GLY A C   1 
ATOM   2171  O O   . GLY A 1 271 ? 0.076   -23.884 -28.111 1.00 27.01  ? 271 GLY A O   1 
ATOM   2172  N N   . PRO A 1 272 ? 2.091   -24.169 -27.102 1.00 29.79  ? 272 PRO A N   1 
ATOM   2173  C CA  . PRO A 1 272 ? 2.893   -23.685 -28.229 1.00 34.36  ? 272 PRO A CA  1 
ATOM   2174  C C   . PRO A 1 272 ? 2.605   -24.248 -29.629 1.00 35.23  ? 272 PRO A C   1 
ATOM   2175  O O   . PRO A 1 272 ? 2.682   -23.524 -30.613 1.00 37.11  ? 272 PRO A O   1 
ATOM   2176  C CB  . PRO A 1 272 ? 4.304   -24.111 -27.827 1.00 35.99  ? 272 PRO A CB  1 
ATOM   2177  C CG  . PRO A 1 272 ? 4.287   -24.035 -26.321 1.00 35.80  ? 272 PRO A CG  1 
ATOM   2178  C CD  . PRO A 1 272 ? 2.920   -24.558 -25.949 1.00 31.26  ? 272 PRO A CD  1 
ATOM   2179  N N   . LEU A 1 273 ? 2.203   -25.516 -29.734 1.00 35.32  ? 273 LEU A N   1 
ATOM   2180  C CA  . LEU A 1 273 ? 1.958   -26.114 -31.043 1.00 34.46  ? 273 LEU A CA  1 
ATOM   2181  C C   . LEU A 1 273 ? 0.536   -25.821 -31.518 1.00 36.86  ? 273 LEU A C   1 
ATOM   2182  O O   . LEU A 1 273 ? 0.180   -26.168 -32.633 1.00 30.67  ? 273 LEU A O   1 
ATOM   2183  C CB  . LEU A 1 273 ? 2.179   -27.634 -30.966 1.00 32.58  ? 273 LEU A CB  1 
ATOM   2184  C CG  . LEU A 1 273 ? 3.581   -28.097 -30.555 1.00 35.38  ? 273 LEU A CG  1 
ATOM   2185  C CD1 . LEU A 1 273 ? 3.698   -29.618 -30.599 1.00 36.63  ? 273 LEU A CD1 1 
ATOM   2186  C CD2 . LEU A 1 273 ? 4.638   -27.490 -31.463 1.00 37.31  ? 273 LEU A CD2 1 
ATOM   2187  N N   . HIS A 1 274 ? -0.305  -25.183 -30.700 1.00 37.08  ? 274 HIS A N   1 
ATOM   2188  C CA  . HIS A 1 274 ? -1.665  -24.908 -31.150 1.00 34.37  ? 274 HIS A CA  1 
ATOM   2189  C C   . HIS A 1 274 ? -1.927  -23.405 -31.284 1.00 38.51  ? 274 HIS A C   1 
ATOM   2190  O O   . HIS A 1 274 ? -2.606  -22.974 -32.210 1.00 39.19  ? 274 HIS A O   1 
ATOM   2191  C CB  . HIS A 1 274 ? -2.652  -25.656 -30.241 1.00 37.31  ? 274 HIS A CB  1 
ATOM   2192  C CG  . HIS A 1 274 ? -4.061  -25.634 -30.713 1.00 37.84  ? 274 HIS A CG  1 
ATOM   2193  N ND1 . HIS A 1 274 ? -4.372  -25.431 -32.032 1.00 34.82  ? 274 HIS A ND1 1 
ATOM   2194  C CD2 . HIS A 1 274 ? -5.241  -25.794 -30.073 1.00 36.82  ? 274 HIS A CD2 1 
ATOM   2195  C CE1 . HIS A 1 274 ? -5.701  -25.434 -32.173 1.00 41.97  ? 274 HIS A CE1 1 
ATOM   2196  N NE2 . HIS A 1 274 ? -6.247  -25.654 -30.998 1.00 36.99  ? 274 HIS A NE2 1 
ATOM   2197  N N   . GLY A 1 275 ? -1.420  -22.566 -30.371 1.00 40.30  ? 275 GLY A N   1 
ATOM   2198  C CA  . GLY A 1 275 ? -1.959  -21.216 -30.287 1.00 33.69  ? 275 GLY A CA  1 
ATOM   2199  C C   . GLY A 1 275 ? -0.926  -20.108 -30.436 1.00 35.08  ? 275 GLY A C   1 
ATOM   2200  O O   . GLY A 1 275 ? -1.267  -18.946 -30.266 1.00 41.21  ? 275 GLY A O   1 
ATOM   2201  N N   . LEU A 1 276 ? 0.317   -20.444 -30.777 1.00 32.28  ? 276 LEU A N   1 
ATOM   2202  C CA  . LEU A 1 276 ? 1.398   -19.470 -30.751 1.00 36.22  ? 276 LEU A CA  1 
ATOM   2203  C C   . LEU A 1 276 ? 1.811   -19.006 -32.160 1.00 38.26  ? 276 LEU A C   1 
ATOM   2204  O O   . LEU A 1 276 ? 2.546   -18.036 -32.305 1.00 39.00  ? 276 LEU A O   1 
ATOM   2205  C CB  . LEU A 1 276 ? 2.539   -20.165 -29.989 1.00 46.34  ? 276 LEU A CB  1 
ATOM   2206  C CG  . LEU A 1 276 ? 3.260   -19.328 -28.941 1.00 61.99  ? 276 LEU A CG  1 
ATOM   2207  C CD1 . LEU A 1 276 ? 4.259   -20.177 -28.174 1.00 64.38  ? 276 LEU A CD1 1 
ATOM   2208  C CD2 . LEU A 1 276 ? 3.961   -18.152 -29.591 1.00 76.08  ? 276 LEU A CD2 1 
ATOM   2209  N N   . ALA A 1 277 ? 1.300   -19.642 -33.219 1.00 34.82  ? 277 ALA A N   1 
ATOM   2210  C CA  . ALA A 1 277 ? 1.816   -19.438 -34.576 1.00 38.02  ? 277 ALA A CA  1 
ATOM   2211  C C   . ALA A 1 277 ? 1.726   -17.979 -35.050 1.00 40.75  ? 277 ALA A C   1 
ATOM   2212  O O   . ALA A 1 277 ? 2.640   -17.496 -35.698 1.00 38.53  ? 277 ALA A O   1 
ATOM   2213  C CB  . ALA A 1 277 ? 1.075   -20.352 -35.518 1.00 37.62  ? 277 ALA A CB  1 
ATOM   2214  N N   . ASN A 1 278 ? 0.611   -17.299 -34.736 1.00 38.63  ? 278 ASN A N   1 
ATOM   2215  C CA  . ASN A 1 278 ? 0.363   -15.879 -34.983 1.00 34.66  ? 278 ASN A CA  1 
ATOM   2216  C C   . ASN A 1 278 ? 1.556   -15.023 -34.564 1.00 35.18  ? 278 ASN A C   1 
ATOM   2217  O O   . ASN A 1 278 ? 2.092   -14.248 -35.367 1.00 35.30  ? 278 ASN A O   1 
ATOM   2218  C CB  . ASN A 1 278 ? -0.891  -15.420 -34.201 1.00 38.56  ? 278 ASN A CB  1 
ATOM   2219  C CG  . ASN A 1 278 ? -1.279  -13.978 -34.446 1.00 47.56  ? 278 ASN A CG  1 
ATOM   2220  O OD1 . ASN A 1 278 ? -0.452  -13.132 -34.806 1.00 56.19  ? 278 ASN A OD1 1 
ATOM   2221  N ND2 . ASN A 1 278 ? -2.536  -13.662 -34.203 1.00 43.51  ? 278 ASN A ND2 1 
ATOM   2222  N N   . GLN A 1 279 ? 1.946   -15.157 -33.296 1.00 32.29  ? 279 GLN A N   1 
ATOM   2223  C CA  . GLN A 1 279 ? 3.013   -14.366 -32.699 1.00 36.46  ? 279 GLN A CA  1 
ATOM   2224  C C   . GLN A 1 279 ? 4.358   -14.702 -33.323 1.00 34.93  ? 279 GLN A C   1 
ATOM   2225  O O   . GLN A 1 279 ? 5.155   -13.797 -33.550 1.00 31.22  ? 279 GLN A O   1 
ATOM   2226  C CB  . GLN A 1 279 ? 3.153   -14.631 -31.205 1.00 40.46  ? 279 GLN A CB  1 
ATOM   2227  C CG  . GLN A 1 279 ? 1.803   -14.703 -30.536 1.00 49.40  ? 279 GLN A CG  1 
ATOM   2228  C CD  . GLN A 1 279 ? 1.875   -15.244 -29.135 1.00 48.22  ? 279 GLN A CD  1 
ATOM   2229  O OE1 . GLN A 1 279 ? 2.900   -15.153 -28.443 1.00 55.82  ? 279 GLN A OE1 1 
ATOM   2230  N NE2 . GLN A 1 279 ? 0.729   -15.749 -28.704 1.00 37.61  ? 279 GLN A NE2 1 
ATOM   2231  N N   . GLU A 1 280 ? 4.599   -15.991 -33.590 1.00 35.71  ? 280 GLU A N   1 
ATOM   2232  C CA  . GLU A 1 280 ? 5.871   -16.414 -34.162 1.00 42.50  ? 280 GLU A CA  1 
ATOM   2233  C C   . GLU A 1 280 ? 6.033   -15.742 -35.515 1.00 37.21  ? 280 GLU A C   1 
ATOM   2234  O O   . GLU A 1 280 ? 7.095   -15.211 -35.800 1.00 38.61  ? 280 GLU A O   1 
ATOM   2235  C CB  . GLU A 1 280 ? 5.988   -17.939 -34.312 1.00 50.80  ? 280 GLU A CB  1 
ATOM   2236  C CG  . GLU A 1 280 ? 6.549   -18.613 -33.065 1.00 63.92  ? 280 GLU A CG  1 
ATOM   2237  C CD  . GLU A 1 280 ? 6.170   -20.066 -32.789 1.00 71.51  ? 280 GLU A CD  1 
ATOM   2238  O OE1 . GLU A 1 280 ? 6.626   -20.576 -31.741 1.00 75.73  ? 280 GLU A OE1 1 
ATOM   2239  O OE2 . GLU A 1 280 ? 5.421   -20.691 -33.602 1.00 62.95  ? 280 GLU A OE2 1 
ATOM   2240  N N   . VAL A 1 281 ? 4.956   -15.745 -36.311 1.00 38.52  ? 281 VAL A N   1 
ATOM   2241  C CA  . VAL A 1 281 ? 4.997   -15.154 -37.635 1.00 36.46  ? 281 VAL A CA  1 
ATOM   2242  C C   . VAL A 1 281 ? 5.320   -13.669 -37.499 1.00 39.62  ? 281 VAL A C   1 
ATOM   2243  O O   . VAL A 1 281 ? 6.259   -13.196 -38.124 1.00 37.40  ? 281 VAL A O   1 
ATOM   2244  C CB  . VAL A 1 281 ? 3.706   -15.395 -38.437 1.00 35.24  ? 281 VAL A CB  1 
ATOM   2245  C CG1 . VAL A 1 281 ? 3.567   -14.456 -39.636 1.00 39.88  ? 281 VAL A CG1 1 
ATOM   2246  C CG2 . VAL A 1 281 ? 3.614   -16.828 -38.923 1.00 38.09  ? 281 VAL A CG2 1 
ATOM   2247  N N   . LEU A 1 282 ? 4.588   -12.936 -36.646 1.00 39.06  ? 282 LEU A N   1 
ATOM   2248  C CA  . LEU A 1 282 ? 4.805   -11.497 -36.547 1.00 34.16  ? 282 LEU A CA  1 
ATOM   2249  C C   . LEU A 1 282 ? 6.255   -11.181 -36.161 1.00 32.76  ? 282 LEU A C   1 
ATOM   2250  O O   . LEU A 1 282 ? 6.892   -10.295 -36.734 1.00 32.16  ? 282 LEU A O   1 
ATOM   2251  C CB  . LEU A 1 282 ? 3.798   -10.903 -35.562 1.00 33.26  ? 282 LEU A CB  1 
ATOM   2252  C CG  . LEU A 1 282 ? 3.959   -9.407  -35.335 1.00 34.38  ? 282 LEU A CG  1 
ATOM   2253  C CD1 . LEU A 1 282 ? 3.775   -8.636  -36.627 1.00 37.18  ? 282 LEU A CD1 1 
ATOM   2254  C CD2 . LEU A 1 282 ? 2.981   -8.913  -34.283 1.00 32.73  ? 282 LEU A CD2 1 
ATOM   2255  N N   . ARG A 1 283 ? 6.803   -11.911 -35.188 1.00 33.07  ? 283 ARG A N   1 
ATOM   2256  C CA  . ARG A 1 283 ? 8.177   -11.677 -34.772 1.00 38.42  ? 283 ARG A CA  1 
ATOM   2257  C C   . ARG A 1 283 ? 9.139   -11.936 -35.937 1.00 36.70  ? 283 ARG A C   1 
ATOM   2258  O O   . ARG A 1 283 ? 10.149  -11.251 -36.095 1.00 36.43  ? 283 ARG A O   1 
ATOM   2259  C CB  . ARG A 1 283 ? 8.513   -12.521 -33.540 1.00 39.93  ? 283 ARG A CB  1 
ATOM   2260  C CG  . ARG A 1 283 ? 7.883   -12.036 -32.244 1.00 42.37  ? 283 ARG A CG  1 
ATOM   2261  C CD  . ARG A 1 283 ? 8.229   -13.010 -31.132 1.00 44.11  ? 283 ARG A CD  1 
ATOM   2262  N NE  . ARG A 1 283 ? 7.595   -12.736 -29.855 1.00 43.78  ? 283 ARG A NE  1 
ATOM   2263  C CZ  . ARG A 1 283 ? 7.960   -11.760 -29.032 1.00 48.50  ? 283 ARG A CZ  1 
ATOM   2264  N NH1 . ARG A 1 283 ? 8.789   -10.820 -29.450 1.00 42.99  ? 283 ARG A NH1 1 
ATOM   2265  N NH2 . ARG A 1 283 ? 7.450   -11.694 -27.812 1.00 43.75  ? 283 ARG A NH2 1 
ATOM   2266  N N   . TRP A 1 284 ? 8.818   -12.934 -36.743 1.00 37.27  ? 284 TRP A N   1 
ATOM   2267  C CA  . TRP A 1 284 ? 9.649   -13.305 -37.875 1.00 38.44  ? 284 TRP A CA  1 
ATOM   2268  C C   . TRP A 1 284 ? 9.620   -12.181 -38.913 1.00 42.52  ? 284 TRP A C   1 
ATOM   2269  O O   . TRP A 1 284 ? 10.671  -11.716 -39.356 1.00 36.63  ? 284 TRP A O   1 
ATOM   2270  C CB  . TRP A 1 284 ? 9.170   -14.656 -38.425 1.00 43.65  ? 284 TRP A CB  1 
ATOM   2271  C CG  . TRP A 1 284 ? 10.053  -15.287 -39.460 1.00 38.65  ? 284 TRP A CG  1 
ATOM   2272  C CD1 . TRP A 1 284 ? 11.180  -16.040 -39.265 1.00 42.45  ? 284 TRP A CD1 1 
ATOM   2273  C CD2 . TRP A 1 284 ? 9.846   -15.222 -40.875 1.00 38.41  ? 284 TRP A CD2 1 
ATOM   2274  N NE1 . TRP A 1 284 ? 11.687  -16.443 -40.471 1.00 40.56  ? 284 TRP A NE1 1 
ATOM   2275  C CE2 . TRP A 1 284 ? 10.896  -15.952 -41.478 1.00 40.12  ? 284 TRP A CE2 1 
ATOM   2276  C CE3 . TRP A 1 284 ? 8.863   -14.635 -41.690 1.00 45.11  ? 284 TRP A CE3 1 
ATOM   2277  C CZ2 . TRP A 1 284 ? 10.982  -16.098 -42.859 1.00 40.06  ? 284 TRP A CZ2 1 
ATOM   2278  C CZ3 . TRP A 1 284 ? 8.942   -14.795 -43.056 1.00 45.51  ? 284 TRP A CZ3 1 
ATOM   2279  C CH2 . TRP A 1 284 ? 9.999   -15.512 -43.628 1.00 44.30  ? 284 TRP A CH2 1 
ATOM   2280  N N   . ILE A 1 285 ? 8.412   -11.684 -39.216 1.00 36.83  ? 285 ILE A N   1 
ATOM   2281  C CA  . ILE A 1 285 ? 8.245   -10.531 -40.080 1.00 39.26  ? 285 ILE A CA  1 
ATOM   2282  C C   . ILE A 1 285 ? 9.053   -9.344  -39.552 1.00 39.86  ? 285 ILE A C   1 
ATOM   2283  O O   . ILE A 1 285 ? 9.726   -8.651  -40.320 1.00 41.89  ? 285 ILE A O   1 
ATOM   2284  C CB  . ILE A 1 285 ? 6.752   -10.196 -40.252 1.00 38.24  ? 285 ILE A CB  1 
ATOM   2285  C CG1 . ILE A 1 285 ? 5.998   -11.323 -40.967 1.00 42.56  ? 285 ILE A CG1 1 
ATOM   2286  C CG2 . ILE A 1 285 ? 6.603   -8.856  -40.953 1.00 36.69  ? 285 ILE A CG2 1 
ATOM   2287  C CD1 . ILE A 1 285 ? 6.279   -11.432 -42.452 1.00 46.19  ? 285 ILE A CD1 1 
ATOM   2288  N N   . GLN A 1 286 ? 9.012   -9.111  -38.237 1.00 38.48  ? 286 GLN A N   1 
ATOM   2289  C CA  . GLN A 1 286 ? 9.692   -7.956  -37.673 1.00 37.27  ? 286 GLN A CA  1 
ATOM   2290  C C   . GLN A 1 286 ? 11.212  -8.155  -37.699 1.00 39.14  ? 286 GLN A C   1 
ATOM   2291  O O   . GLN A 1 286 ? 11.965  -7.173  -37.767 1.00 36.40  ? 286 GLN A O   1 
ATOM   2292  C CB  . GLN A 1 286 ? 9.208   -7.678  -36.247 1.00 36.49  ? 286 GLN A CB  1 
ATOM   2293  C CG  . GLN A 1 286 ? 7.781   -7.126  -36.186 1.00 36.19  ? 286 GLN A CG  1 
ATOM   2294  C CD  . GLN A 1 286 ? 7.202   -7.252  -34.791 1.00 42.02  ? 286 GLN A CD  1 
ATOM   2295  O OE1 . GLN A 1 286 ? 7.367   -8.276  -34.118 1.00 36.47  ? 286 GLN A OE1 1 
ATOM   2296  N NE2 . GLN A 1 286 ? 6.555   -6.190  -34.330 1.00 37.24  ? 286 GLN A NE2 1 
ATOM   2297  N N   . MET A 1 287 ? 11.662  -9.410  -37.579 1.00 37.78  ? 287 MET A N   1 
ATOM   2298  C CA  . MET A 1 287 ? 13.076  -9.749  -37.687 1.00 43.20  ? 287 MET A CA  1 
ATOM   2299  C C   . MET A 1 287 ? 13.562  -9.415  -39.100 1.00 44.22  ? 287 MET A C   1 
ATOM   2300  O O   . MET A 1 287 ? 14.639  -8.837  -39.240 1.00 44.44  ? 287 MET A O   1 
ATOM   2301  C CB  . MET A 1 287 ? 13.345  -11.221 -37.315 1.00 44.74  ? 287 MET A CB  1 
ATOM   2302  C CG  . MET A 1 287 ? 14.769  -11.740 -37.630 1.00 46.19  ? 287 MET A CG  1 
ATOM   2303  S SD  . MET A 1 287 ? 14.899  -12.221 -39.387 1.00 47.15  ? 287 MET A SD  1 
ATOM   2304  C CE  . MET A 1 287 ? 13.783  -13.624 -39.415 1.00 46.82  ? 287 MET A CE  1 
ATOM   2305  N N   . LEU A 1 288 ? 12.757  -9.712  -40.131 1.00 41.62  ? 288 LEU A N   1 
ATOM   2306  C CA  . LEU A 1 288 ? 13.130  -9.392  -41.503 1.00 42.13  ? 288 LEU A CA  1 
ATOM   2307  C C   . LEU A 1 288 ? 13.300  -7.890  -41.688 1.00 50.57  ? 288 LEU A C   1 
ATOM   2308  O O   . LEU A 1 288 ? 14.329  -7.430  -42.196 1.00 43.27  ? 288 LEU A O   1 
ATOM   2309  C CB  . LEU A 1 288 ? 12.068  -9.918  -42.472 1.00 43.98  ? 288 LEU A CB  1 
ATOM   2310  C CG  . LEU A 1 288 ? 12.119  -11.422 -42.704 1.00 47.55  ? 288 LEU A CG  1 
ATOM   2311  C CD1 . LEU A 1 288 ? 10.929  -11.901 -43.522 1.00 46.74  ? 288 LEU A CD1 1 
ATOM   2312  C CD2 . LEU A 1 288 ? 13.426  -11.801 -43.392 1.00 52.15  ? 288 LEU A CD2 1 
ATOM   2313  N N   . TYR A 1 289 ? 12.269  -7.133  -41.286 1.00 44.61  ? 289 TYR A N   1 
ATOM   2314  C CA  . TYR A 1 289 ? 12.298  -5.679  -41.360 1.00 42.44  ? 289 TYR A CA  1 
ATOM   2315  C C   . TYR A 1 289 ? 13.590  -5.124  -40.758 1.00 41.08  ? 289 TYR A C   1 
ATOM   2316  O O   . TYR A 1 289 ? 14.242  -4.257  -41.330 1.00 42.06  ? 289 TYR A O   1 
ATOM   2317  C CB  . TYR A 1 289 ? 11.042  -5.112  -40.689 1.00 48.18  ? 289 TYR A CB  1 
ATOM   2318  C CG  . TYR A 1 289 ? 10.888  -3.619  -40.781 1.00 49.42  ? 289 TYR A CG  1 
ATOM   2319  C CD1 . TYR A 1 289 ? 10.314  -3.022  -41.889 1.00 52.92  ? 289 TYR A CD1 1 
ATOM   2320  C CD2 . TYR A 1 289 ? 11.350  -2.812  -39.762 1.00 52.18  ? 289 TYR A CD2 1 
ATOM   2321  C CE1 . TYR A 1 289 ? 10.184  -1.646  -41.978 1.00 57.70  ? 289 TYR A CE1 1 
ATOM   2322  C CE2 . TYR A 1 289 ? 11.239  -1.438  -39.834 1.00 68.78  ? 289 TYR A CE2 1 
ATOM   2323  C CZ  . TYR A 1 289 ? 10.659  -0.855  -40.947 1.00 66.68  ? 289 TYR A CZ  1 
ATOM   2324  O OH  . TYR A 1 289 ? 10.552  0.502   -40.973 1.00 65.57  ? 289 TYR A OH  1 
ATOM   2325  N N   . LYS A 1 290 ? 13.945  -5.589  -39.569 1.00 45.10  ? 290 LYS A N   1 
ATOM   2326  C CA  . LYS A 1 290 ? 15.123  -5.091  -38.880 1.00 48.93  ? 290 LYS A CA  1 
ATOM   2327  C C   . LYS A 1 290 ? 16.382  -5.596  -39.598 1.00 49.83  ? 290 LYS A C   1 
ATOM   2328  O O   . LYS A 1 290 ? 17.363  -4.883  -39.701 1.00 46.22  ? 290 LYS A O   1 
ATOM   2329  C CB  . LYS A 1 290 ? 15.079  -5.538  -37.418 1.00 51.19  ? 290 LYS A CB  1 
ATOM   2330  C CG  . LYS A 1 290 ? 16.322  -5.203  -36.612 1.00 55.46  ? 290 LYS A CG  1 
ATOM   2331  C CD  . LYS A 1 290 ? 16.320  -5.757  -35.201 1.00 57.82  ? 290 LYS A CD  1 
ATOM   2332  C CE  . LYS A 1 290 ? 17.314  -5.036  -34.319 1.00 59.77  ? 290 LYS A CE  1 
ATOM   2333  N NZ  . LYS A 1 290 ? 17.468  -5.721  -33.017 1.00 69.82  ? 290 LYS A NZ  1 
ATOM   2334  N N   . LYS A 1 291 ? 16.358  -6.824  -40.119 1.00 50.62  ? 291 LYS A N   1 
ATOM   2335  C CA  . LYS A 1 291 ? 17.536  -7.372  -40.773 1.00 49.41  ? 291 LYS A CA  1 
ATOM   2336  C C   . LYS A 1 291 ? 17.865  -6.577  -42.043 1.00 48.30  ? 291 LYS A C   1 
ATOM   2337  O O   . LYS A 1 291 ? 19.032  -6.322  -42.303 1.00 50.46  ? 291 LYS A O   1 
ATOM   2338  C CB  . LYS A 1 291 ? 17.358  -8.863  -41.062 1.00 49.55  ? 291 LYS A CB  1 
ATOM   2339  C CG  . LYS A 1 291 ? 18.508  -9.509  -41.831 1.00 54.27  ? 291 LYS A CG  1 
ATOM   2340  C CD  . LYS A 1 291 ? 18.296  -10.989 -42.076 1.00 63.05  ? 291 LYS A CD  1 
ATOM   2341  C CE  . LYS A 1 291 ? 19.426  -11.642 -42.846 1.00 65.25  ? 291 LYS A CE  1 
ATOM   2342  N NZ  . LYS A 1 291 ? 20.712  -11.506 -42.129 1.00 63.67  ? 291 LYS A NZ  1 
ATOM   2343  N N   . PHE A 1 292 ? 16.853  -6.123  -42.797 1.00 48.18  ? 292 PHE A N   1 
ATOM   2344  C CA  . PHE A 1 292 ? 17.079  -5.491  -44.093 1.00 52.22  ? 292 PHE A CA  1 
ATOM   2345  C C   . PHE A 1 292 ? 16.874  -3.979  -44.068 1.00 54.25  ? 292 PHE A C   1 
ATOM   2346  O O   . PHE A 1 292 ? 16.806  -3.377  -45.132 1.00 59.82  ? 292 PHE A O   1 
ATOM   2347  C CB  . PHE A 1 292 ? 16.159  -6.116  -45.140 1.00 46.25  ? 292 PHE A CB  1 
ATOM   2348  C CG  . PHE A 1 292 ? 16.532  -7.538  -45.441 1.00 51.69  ? 292 PHE A CG  1 
ATOM   2349  C CD1 . PHE A 1 292 ? 17.673  -7.817  -46.182 1.00 59.97  ? 292 PHE A CD1 1 
ATOM   2350  C CD2 . PHE A 1 292 ? 15.804  -8.597  -44.926 1.00 51.02  ? 292 PHE A CD2 1 
ATOM   2351  C CE1 . PHE A 1 292 ? 18.032  -9.128  -46.464 1.00 56.38  ? 292 PHE A CE1 1 
ATOM   2352  C CE2 . PHE A 1 292 ? 16.166  -9.910  -45.203 1.00 51.03  ? 292 PHE A CE2 1 
ATOM   2353  C CZ  . PHE A 1 292 ? 17.275  -10.172 -45.973 1.00 58.00  ? 292 PHE A CZ  1 
ATOM   2354  N N   . GLY A 1 293 ? 16.742  -3.379  -42.875 1.00 55.78  ? 293 GLY A N   1 
ATOM   2355  C CA  . GLY A 1 293 ? 16.491  -1.951  -42.747 1.00 50.84  ? 293 GLY A CA  1 
ATOM   2356  C C   . GLY A 1 293 ? 15.257  -1.491  -43.523 1.00 50.63  ? 293 GLY A C   1 
ATOM   2357  O O   . GLY A 1 293 ? 15.217  -0.389  -44.054 1.00 60.25  ? 293 GLY A O   1 
ATOM   2358  N N   . GLY A 1 294 ? 14.239  -2.338  -43.583 1.00 50.98  ? 294 GLY A N   1 
ATOM   2359  C CA  . GLY A 1 294 ? 13.045  -2.048  -44.349 1.00 46.21  ? 294 GLY A CA  1 
ATOM   2360  C C   . GLY A 1 294 ? 12.559  -3.310  -45.044 1.00 46.26  ? 294 GLY A C   1 
ATOM   2361  O O   . GLY A 1 294 ? 12.893  -4.417  -44.626 1.00 54.35  ? 294 GLY A O   1 
ATOM   2362  N N   . VAL A 1 295 ? 11.769  -3.131  -46.096 1.00 48.26  ? 295 VAL A N   1 
ATOM   2363  C CA  . VAL A 1 295 ? 11.256  -4.251  -46.866 1.00 54.79  ? 295 VAL A CA  1 
ATOM   2364  C C   . VAL A 1 295 ? 12.391  -4.824  -47.712 1.00 59.19  ? 295 VAL A C   1 
ATOM   2365  O O   . VAL A 1 295 ? 13.039  -4.092  -48.450 1.00 67.27  ? 295 VAL A O   1 
ATOM   2366  C CB  . VAL A 1 295 ? 10.078  -3.825  -47.759 1.00 51.72  ? 295 VAL A CB  1 
ATOM   2367  C CG1 . VAL A 1 295 ? 9.519   -5.018  -48.519 1.00 57.20  ? 295 VAL A CG1 1 
ATOM   2368  C CG2 . VAL A 1 295 ? 8.990   -3.114  -46.970 1.00 53.16  ? 295 VAL A CG2 1 
ATOM   2369  N N   . PRO A 1 296 ? 12.674  -6.144  -47.634 1.00 60.61  ? 296 PRO A N   1 
ATOM   2370  C CA  . PRO A 1 296 ? 13.632  -6.763  -48.539 1.00 58.51  ? 296 PRO A CA  1 
ATOM   2371  C C   . PRO A 1 296 ? 13.121  -6.821  -49.978 1.00 60.75  ? 296 PRO A C   1 
ATOM   2372  O O   . PRO A 1 296 ? 11.914  -6.727  -50.216 1.00 51.41  ? 296 PRO A O   1 
ATOM   2373  C CB  . PRO A 1 296 ? 13.839  -8.178  -47.969 1.00 62.70  ? 296 PRO A CB  1 
ATOM   2374  C CG  . PRO A 1 296 ? 12.649  -8.439  -47.059 1.00 58.78  ? 296 PRO A CG  1 
ATOM   2375  C CD  . PRO A 1 296 ? 12.126  -7.087  -46.648 1.00 57.94  ? 296 PRO A CD  1 
ATOM   2376  N N   . THR A 1 297 ? 14.071  -6.971  -50.917 1.00 57.24  ? 297 THR A N   1 
ATOM   2377  C CA  . THR A 1 297 ? 13.792  -7.315  -52.310 1.00 59.27  ? 297 THR A CA  1 
ATOM   2378  C C   . THR A 1 297 ? 13.450  -8.805  -52.428 1.00 59.87  ? 297 THR A C   1 
ATOM   2379  O O   . THR A 1 297 ? 13.755  -9.616  -51.530 1.00 51.00  ? 297 THR A O   1 
ATOM   2380  C CB  . THR A 1 297 ? 14.994  -7.008  -53.226 1.00 56.64  ? 297 THR A CB  1 
ATOM   2381  O OG1 . THR A 1 297 ? 16.041  -7.918  -52.873 1.00 54.69  ? 297 THR A OG1 1 
ATOM   2382  C CG2 . THR A 1 297 ? 15.507  -5.582  -53.131 1.00 52.61  ? 297 THR A CG2 1 
ATOM   2383  N N   . LYS A 1 298 ? 12.860  -9.158  -53.582 1.00 62.38  ? 298 LYS A N   1 
ATOM   2384  C CA  . LYS A 1 298 ? 12.536  -10.540 -53.914 1.00 63.39  ? 298 LYS A CA  1 
ATOM   2385  C C   . LYS A 1 298 ? 13.757  -11.448 -53.742 1.00 67.92  ? 298 LYS A C   1 
ATOM   2386  O O   . LYS A 1 298 ? 13.634  -12.534 -53.164 1.00 64.75  ? 298 LYS A O   1 
ATOM   2387  C CB  . LYS A 1 298 ? 11.945  -10.611 -55.327 1.00 71.01  ? 298 LYS A CB  1 
ATOM   2388  C CG  . LYS A 1 298 ? 10.435  -10.826 -55.390 1.00 80.93  ? 298 LYS A CG  1 
ATOM   2389  C CD  . LYS A 1 298 ? 9.720   -10.009 -56.454 1.00 88.31  ? 298 LYS A CD  1 
ATOM   2390  C CE  . LYS A 1 298 ? 9.588   -8.544  -56.080 1.00 88.00  ? 298 LYS A CE  1 
ATOM   2391  N NZ  . LYS A 1 298 ? 8.746   -7.808  -57.052 1.00 93.57  ? 298 LYS A NZ  1 
ATOM   2392  N N   . GLU A 1 299 ? 14.932  -10.979 -54.197 1.00 65.48  ? 299 GLU A N   1 
ATOM   2393  C CA  . GLU A 1 299 ? 16.147  -11.790 -54.231 1.00 68.18  ? 299 GLU A CA  1 
ATOM   2394  C C   . GLU A 1 299 ? 16.701  -11.975 -52.824 1.00 57.26  ? 299 GLU A C   1 
ATOM   2395  O O   . GLU A 1 299 ? 17.148  -13.067 -52.485 1.00 58.00  ? 299 GLU A O   1 
ATOM   2396  C CB  . GLU A 1 299 ? 17.269  -11.149 -55.058 1.00 78.57  ? 299 GLU A CB  1 
ATOM   2397  C CG  . GLU A 1 299 ? 16.918  -10.894 -56.513 1.00 85.37  ? 299 GLU A CG  1 
ATOM   2398  C CD  . GLU A 1 299 ? 15.711  -9.995  -56.733 1.00 85.93  ? 299 GLU A CD  1 
ATOM   2399  O OE1 . GLU A 1 299 ? 14.858  -10.358 -57.561 1.00 86.29  ? 299 GLU A OE1 1 
ATOM   2400  O OE2 . GLU A 1 299 ? 15.610  -8.950  -56.048 1.00 87.41  ? 299 GLU A OE2 1 
ATOM   2401  N N   . GLN A 1 300 ? 16.701  -10.895 -52.027 1.00 56.66  ? 300 GLN A N   1 
ATOM   2402  C CA  . GLN A 1 300 ? 17.084  -10.982 -50.622 1.00 57.27  ? 300 GLN A CA  1 
ATOM   2403  C C   . GLN A 1 300 ? 16.198  -11.992 -49.886 1.00 49.72  ? 300 GLN A C   1 
ATOM   2404  O O   . GLN A 1 300 ? 16.684  -12.839 -49.126 1.00 48.86  ? 300 GLN A O   1 
ATOM   2405  C CB  . GLN A 1 300 ? 16.985  -9.610  -49.960 1.00 58.47  ? 300 GLN A CB  1 
ATOM   2406  C CG  . GLN A 1 300 ? 18.110  -8.653  -50.336 1.00 62.20  ? 300 GLN A CG  1 
ATOM   2407  C CD  . GLN A 1 300 ? 17.850  -7.245  -49.851 1.00 53.94  ? 300 GLN A CD  1 
ATOM   2408  O OE1 . GLN A 1 300 ? 16.751  -6.712  -49.961 1.00 61.76  ? 300 GLN A OE1 1 
ATOM   2409  N NE2 . GLN A 1 300 ? 18.868  -6.615  -49.303 1.00 58.61  ? 300 GLN A NE2 1 
ATOM   2410  N N   . LEU A 1 301 ? 14.886  -11.897 -50.111 1.00 52.29  ? 301 LEU A N   1 
ATOM   2411  C CA  . LEU A 1 301 ? 13.953  -12.736 -49.373 1.00 54.65  ? 301 LEU A CA  1 
ATOM   2412  C C   . LEU A 1 301 ? 14.119  -14.183 -49.831 1.00 57.01  ? 301 LEU A C   1 
ATOM   2413  O O   . LEU A 1 301 ? 14.163  -15.098 -49.001 1.00 49.47  ? 301 LEU A O   1 
ATOM   2414  C CB  . LEU A 1 301 ? 12.515  -12.225 -49.539 1.00 52.43  ? 301 LEU A CB  1 
ATOM   2415  C CG  . LEU A 1 301 ? 11.451  -13.062 -48.812 1.00 61.40  ? 301 LEU A CG  1 
ATOM   2416  C CD1 . LEU A 1 301 ? 11.680  -13.093 -47.300 1.00 57.62  ? 301 LEU A CD1 1 
ATOM   2417  C CD2 . LEU A 1 301 ? 10.049  -12.562 -49.118 1.00 61.48  ? 301 LEU A CD2 1 
ATOM   2418  N N   . GLU A 1 302 ? 14.260  -14.374 -51.151 1.00 62.42  ? 302 GLU A N   1 
ATOM   2419  C CA  . GLU A 1 302 ? 14.452  -15.704 -51.708 1.00 63.68  ? 302 GLU A CA  1 
ATOM   2420  C C   . GLU A 1 302 ? 15.674  -16.347 -51.049 1.00 63.40  ? 302 GLU A C   1 
ATOM   2421  O O   . GLU A 1 302 ? 15.607  -17.461 -50.517 1.00 59.63  ? 302 GLU A O   1 
ATOM   2422  C CB  . GLU A 1 302 ? 14.604  -15.643 -53.232 1.00 69.86  ? 302 GLU A CB  1 
ATOM   2423  C CG  . GLU A 1 302 ? 14.807  -17.021 -53.872 1.00 70.38  ? 302 GLU A CG  1 
ATOM   2424  C CD  . GLU A 1 302 ? 15.157  -17.016 -55.355 1.00 65.47  ? 302 GLU A CD  1 
ATOM   2425  O OE1 . GLU A 1 302 ? 14.500  -17.738 -56.123 1.00 69.32  ? 302 GLU A OE1 1 
ATOM   2426  O OE2 . GLU A 1 302 ? 16.077  -16.277 -55.745 1.00 74.16  ? 302 GLU A OE2 1 
ATOM   2427  N N   . ARG A 1 303 ? 16.790  -15.613 -51.065 1.00 63.88  ? 303 ARG A N   1 
ATOM   2428  C CA  . ARG A 1 303 ? 18.021  -16.107 -50.481 1.00 64.50  ? 303 ARG A CA  1 
ATOM   2429  C C   . ARG A 1 303 ? 17.801  -16.415 -49.008 1.00 60.76  ? 303 ARG A C   1 
ATOM   2430  O O   . ARG A 1 303 ? 18.286  -17.440 -48.529 1.00 55.68  ? 303 ARG A O   1 
ATOM   2431  C CB  . ARG A 1 303 ? 19.171  -15.104 -50.622 1.00 65.10  ? 303 ARG A CB  1 
ATOM   2432  C CG  . ARG A 1 303 ? 19.783  -15.051 -52.014 1.00 70.35  ? 303 ARG A CG  1 
ATOM   2433  C CD  . ARG A 1 303 ? 21.236  -14.617 -51.933 1.00 74.39  ? 303 ARG A CD  1 
ATOM   2434  N NE  . ARG A 1 303 ? 21.430  -13.371 -51.197 1.00 62.86  ? 303 ARG A NE  1 
ATOM   2435  C CZ  . ARG A 1 303 ? 21.177  -12.162 -51.688 1.00 73.05  ? 303 ARG A CZ  1 
ATOM   2436  N NH1 . ARG A 1 303 ? 21.181  -11.103 -50.892 1.00 78.43  ? 303 ARG A NH1 1 
ATOM   2437  N NH2 . ARG A 1 303 ? 20.884  -12.026 -52.970 1.00 71.04  ? 303 ARG A NH2 1 
ATOM   2438  N N   . PHE A 1 304 ? 17.107  -15.514 -48.289 1.00 57.72  ? 304 PHE A N   1 
ATOM   2439  C CA  . PHE A 1 304 ? 16.928  -15.712 -46.857 1.00 50.66  ? 304 PHE A CA  1 
ATOM   2440  C C   . PHE A 1 304 ? 16.192  -17.029 -46.622 1.00 44.19  ? 304 PHE A C   1 
ATOM   2441  O O   . PHE A 1 304 ? 16.516  -17.768 -45.697 1.00 43.95  ? 304 PHE A O   1 
ATOM   2442  C CB  . PHE A 1 304 ? 16.195  -14.539 -46.191 1.00 53.65  ? 304 PHE A CB  1 
ATOM   2443  C CG  . PHE A 1 304 ? 16.108  -14.669 -44.693 1.00 50.43  ? 304 PHE A CG  1 
ATOM   2444  C CD1 . PHE A 1 304 ? 17.154  -14.271 -43.891 1.00 51.12  ? 304 PHE A CD1 1 
ATOM   2445  C CD2 . PHE A 1 304 ? 15.023  -15.293 -44.100 1.00 52.61  ? 304 PHE A CD2 1 
ATOM   2446  C CE1 . PHE A 1 304 ? 17.084  -14.432 -42.516 1.00 58.70  ? 304 PHE A CE1 1 
ATOM   2447  C CE2 . PHE A 1 304 ? 14.966  -15.484 -42.731 1.00 46.62  ? 304 PHE A CE2 1 
ATOM   2448  C CZ  . PHE A 1 304 ? 15.988  -15.031 -41.940 1.00 54.43  ? 304 PHE A CZ  1 
ATOM   2449  N N   . ALA A 1 305 ? 15.170  -17.296 -47.443 1.00 43.39  ? 305 ALA A N   1 
ATOM   2450  C CA  . ALA A 1 305 ? 14.303  -18.443 -47.230 1.00 44.90  ? 305 ALA A CA  1 
ATOM   2451  C C   . ALA A 1 305 ? 15.117  -19.739 -47.345 1.00 54.21  ? 305 ALA A C   1 
ATOM   2452  O O   . ALA A 1 305 ? 15.066  -20.630 -46.477 1.00 53.39  ? 305 ALA A O   1 
ATOM   2453  C CB  . ALA A 1 305 ? 13.182  -18.384 -48.238 1.00 46.79  ? 305 ALA A CB  1 
ATOM   2454  N N   . TRP A 1 306 ? 15.922  -19.784 -48.411 1.00 56.50  ? 306 TRP A N   1 
ATOM   2455  C CA  . TRP A 1 306 ? 16.835  -20.884 -48.682 1.00 52.32  ? 306 TRP A CA  1 
ATOM   2456  C C   . TRP A 1 306 ? 17.833  -21.070 -47.546 1.00 50.99  ? 306 TRP A C   1 
ATOM   2457  O O   . TRP A 1 306 ? 17.963  -22.171 -47.000 1.00 51.52  ? 306 TRP A O   1 
ATOM   2458  C CB  . TRP A 1 306 ? 17.517  -20.636 -50.021 1.00 49.33  ? 306 TRP A CB  1 
ATOM   2459  C CG  . TRP A 1 306 ? 16.655  -21.012 -51.185 1.00 44.87  ? 306 TRP A CG  1 
ATOM   2460  C CD1 . TRP A 1 306 ? 16.187  -20.205 -52.188 1.00 46.48  ? 306 TRP A CD1 1 
ATOM   2461  C CD2 . TRP A 1 306 ? 16.229  -22.344 -51.504 1.00 49.22  ? 306 TRP A CD2 1 
ATOM   2462  N NE1 . TRP A 1 306 ? 15.476  -20.942 -53.098 1.00 52.18  ? 306 TRP A NE1 1 
ATOM   2463  C CE2 . TRP A 1 306 ? 15.489  -22.261 -52.706 1.00 50.57  ? 306 TRP A CE2 1 
ATOM   2464  C CE3 . TRP A 1 306 ? 16.384  -23.589 -50.877 1.00 49.93  ? 306 TRP A CE3 1 
ATOM   2465  C CZ2 . TRP A 1 306 ? 14.891  -23.384 -53.279 1.00 52.10  ? 306 TRP A CZ2 1 
ATOM   2466  C CZ3 . TRP A 1 306 ? 15.799  -24.698 -51.453 1.00 56.55  ? 306 TRP A CZ3 1 
ATOM   2467  C CH2 . TRP A 1 306 ? 15.072  -24.593 -52.644 1.00 55.66  ? 306 TRP A CH2 1 
ATOM   2468  N N   . ASP A 1 307 ? 18.496  -19.985 -47.145 1.00 52.43  ? 307 ASP A N   1 
ATOM   2469  C CA  . ASP A 1 307 ? 19.405  -20.054 -46.008 1.00 56.75  ? 307 ASP A CA  1 
ATOM   2470  C C   . ASP A 1 307 ? 18.689  -20.579 -44.758 1.00 55.72  ? 307 ASP A C   1 
ATOM   2471  O O   . ASP A 1 307 ? 19.297  -21.304 -43.963 1.00 49.45  ? 307 ASP A O   1 
ATOM   2472  C CB  . ASP A 1 307 ? 20.098  -18.705 -45.783 1.00 61.29  ? 307 ASP A CB  1 
ATOM   2473  C CG  . ASP A 1 307 ? 20.956  -18.261 -46.965 1.00 70.36  ? 307 ASP A CG  1 
ATOM   2474  O OD1 . ASP A 1 307 ? 21.008  -18.999 -48.000 1.00 65.70  ? 307 ASP A OD1 1 
ATOM   2475  O OD2 . ASP A 1 307 ? 21.563  -17.175 -46.855 1.00 67.13  ? 307 ASP A OD2 1 
ATOM   2476  N N   . THR A 1 308 ? 17.402  -20.223 -44.581 1.00 67.58  ? 308 THR A N   1 
ATOM   2477  C CA  . THR A 1 308 ? 16.630  -20.614 -43.399 1.00 68.44  ? 308 THR A CA  1 
ATOM   2478  C C   . THR A 1 308 ? 16.405  -22.131 -43.363 1.00 57.43  ? 308 THR A C   1 
ATOM   2479  O O   . THR A 1 308 ? 16.723  -22.783 -42.360 1.00 54.95  ? 308 THR A O   1 
ATOM   2480  C CB  . THR A 1 308 ? 15.274  -19.883 -43.328 1.00 73.60  ? 308 THR A CB  1 
ATOM   2481  O OG1 . THR A 1 308 ? 15.454  -18.470 -43.412 1.00 76.26  ? 308 THR A OG1 1 
ATOM   2482  C CG2 . THR A 1 308 ? 14.509  -20.168 -42.054 1.00 78.14  ? 308 THR A CG2 1 
ATOM   2483  N N   . LEU A 1 309 ? 15.825  -22.662 -44.454 1.00 49.65  ? 309 LEU A N   1 
ATOM   2484  C CA  . LEU A 1 309 ? 15.497  -24.075 -44.605 1.00 59.57  ? 309 LEU A CA  1 
ATOM   2485  C C   . LEU A 1 309 ? 16.757  -24.948 -44.534 1.00 65.57  ? 309 LEU A C   1 
ATOM   2486  O O   . LEU A 1 309 ? 16.795  -25.940 -43.802 1.00 62.58  ? 309 LEU A O   1 
ATOM   2487  C CB  . LEU A 1 309 ? 14.783  -24.250 -45.950 1.00 65.95  ? 309 LEU A CB  1 
ATOM   2488  C CG  . LEU A 1 309 ? 13.457  -23.501 -46.067 1.00 68.39  ? 309 LEU A CG  1 
ATOM   2489  C CD1 . LEU A 1 309 ? 12.915  -23.550 -47.488 1.00 67.83  ? 309 LEU A CD1 1 
ATOM   2490  C CD2 . LEU A 1 309 ? 12.450  -24.076 -45.081 1.00 69.30  ? 309 LEU A CD2 1 
ATOM   2491  N N   . ASN A 1 310 ? 17.809  -24.554 -45.260 1.00 61.12  ? 310 ASN A N   1 
ATOM   2492  C CA  . ASN A 1 310 ? 19.043  -25.322 -45.284 1.00 61.70  ? 310 ASN A CA  1 
ATOM   2493  C C   . ASN A 1 310 ? 19.778  -25.200 -43.956 1.00 65.45  ? 310 ASN A C   1 
ATOM   2494  O O   . ASN A 1 310 ? 20.712  -25.962 -43.742 1.00 69.72  ? 310 ASN A O   1 
ATOM   2495  C CB  . ASN A 1 310 ? 19.950  -24.927 -46.453 1.00 57.90  ? 310 ASN A CB  1 
ATOM   2496  C CG  . ASN A 1 310 ? 19.316  -25.288 -47.775 1.00 57.85  ? 310 ASN A CG  1 
ATOM   2497  O OD1 . ASN A 1 310 ? 18.665  -26.325 -47.868 1.00 67.24  ? 310 ASN A OD1 1 
ATOM   2498  N ND2 . ASN A 1 310 ? 19.443  -24.429 -48.774 1.00 60.45  ? 310 ASN A ND2 1 
ATOM   2499  N N   . SER A 1 311 ? 19.361  -24.284 -43.061 1.00 64.25  ? 311 SER A N   1 
ATOM   2500  C CA  . SER A 1 311 ? 19.921  -24.261 -41.713 1.00 67.33  ? 311 SER A CA  1 
ATOM   2501  C C   . SER A 1 311 ? 19.022  -25.007 -40.721 1.00 65.73  ? 311 SER A C   1 
ATOM   2502  O O   . SER A 1 311 ? 19.202  -24.862 -39.512 1.00 67.66  ? 311 SER A O   1 
ATOM   2503  C CB  . SER A 1 311 ? 20.242  -22.855 -41.247 1.00 79.39  ? 311 SER A CB  1 
ATOM   2504  O OG  . SER A 1 311 ? 19.074  -22.143 -40.871 1.00 90.30  ? 311 SER A OG  1 
ATOM   2505  N N   . GLY A 1 312 ? 18.078  -25.815 -41.240 1.00 63.77  ? 312 GLY A N   1 
ATOM   2506  C CA  . GLY A 1 312 ? 17.216  -26.672 -40.434 1.00 69.51  ? 312 GLY A CA  1 
ATOM   2507  C C   . GLY A 1 312 ? 15.997  -25.958 -39.834 1.00 76.87  ? 312 GLY A C   1 
ATOM   2508  O O   . GLY A 1 312 ? 15.309  -26.527 -38.983 1.00 62.92  ? 312 GLY A O   1 
ATOM   2509  N N   . GLN A 1 313 ? 15.702  -24.723 -40.268 1.00 75.19  ? 313 GLN A N   1 
ATOM   2510  C CA  . GLN A 1 313 ? 14.632  -23.963 -39.635 1.00 70.39  ? 313 GLN A CA  1 
ATOM   2511  C C   . GLN A 1 313 ? 13.339  -24.105 -40.436 1.00 62.23  ? 313 GLN A C   1 
ATOM   2512  O O   . GLN A 1 313 ? 13.348  -24.473 -41.618 1.00 56.14  ? 313 GLN A O   1 
ATOM   2513  C CB  . GLN A 1 313 ? 15.010  -22.489 -39.460 1.00 72.83  ? 313 GLN A CB  1 
ATOM   2514  C CG  . GLN A 1 313 ? 16.317  -22.256 -38.710 1.00 85.10  ? 313 GLN A CG  1 
ATOM   2515  C CD  . GLN A 1 313 ? 16.278  -22.624 -37.245 1.00 91.65  ? 313 GLN A CD  1 
ATOM   2516  O OE1 . GLN A 1 313 ? 16.427  -21.772 -36.371 1.00 90.79  ? 313 GLN A OE1 1 
ATOM   2517  N NE2 . GLN A 1 313 ? 16.109  -23.906 -36.961 1.00 91.18  ? 313 GLN A NE2 1 
ATOM   2518  N N   . VAL A 1 314 ? 12.229  -23.799 -39.744 1.00 62.41  ? 314 VAL A N   1 
ATOM   2519  C CA  . VAL A 1 314 ? 10.904  -23.732 -40.344 1.00 63.76  ? 314 VAL A CA  1 
ATOM   2520  C C   . VAL A 1 314 ? 10.562  -22.273 -40.675 1.00 55.19  ? 314 VAL A C   1 
ATOM   2521  O O   . VAL A 1 314 ? 10.857  -21.385 -39.889 1.00 53.78  ? 314 VAL A O   1 
ATOM   2522  C CB  . VAL A 1 314 ? 9.838   -24.366 -39.421 1.00 69.99  ? 314 VAL A CB  1 
ATOM   2523  C CG1 . VAL A 1 314 ? 10.095  -25.857 -39.201 1.00 71.70  ? 314 VAL A CG1 1 
ATOM   2524  C CG2 . VAL A 1 314 ? 9.700   -23.634 -38.083 1.00 71.36  ? 314 VAL A CG2 1 
ATOM   2525  N N   . ILE A 1 315 ? 9.917   -22.051 -41.828 1.00 51.31  ? 315 ILE A N   1 
ATOM   2526  C CA  . ILE A 1 315 ? 9.310   -20.776 -42.196 1.00 55.57  ? 315 ILE A CA  1 
ATOM   2527  C C   . ILE A 1 315 ? 7.907   -20.635 -41.578 1.00 57.58  ? 315 ILE A C   1 
ATOM   2528  O O   . ILE A 1 315 ? 6.941   -21.252 -42.045 1.00 54.81  ? 315 ILE A O   1 
ATOM   2529  C CB  . ILE A 1 315 ? 9.246   -20.666 -43.729 1.00 47.16  ? 315 ILE A CB  1 
ATOM   2530  C CG1 . ILE A 1 315 ? 10.656  -20.631 -44.324 1.00 54.97  ? 315 ILE A CG1 1 
ATOM   2531  C CG2 . ILE A 1 315 ? 8.422   -19.467 -44.161 1.00 49.31  ? 315 ILE A CG2 1 
ATOM   2532  C CD1 . ILE A 1 315 ? 10.675  -20.395 -45.812 1.00 57.89  ? 315 ILE A CD1 1 
ATOM   2533  N N   . PRO A 1 316 ? 7.696   -19.762 -40.565 1.00 56.29  ? 316 PRO A N   1 
ATOM   2534  C CA  . PRO A 1 316 ? 6.394   -19.722 -39.890 1.00 54.79  ? 316 PRO A CA  1 
ATOM   2535  C C   . PRO A 1 316 ? 5.284   -19.172 -40.796 1.00 44.92  ? 316 PRO A C   1 
ATOM   2536  O O   . PRO A 1 316 ? 5.507   -18.300 -41.634 1.00 44.76  ? 316 PRO A O   1 
ATOM   2537  C CB  . PRO A 1 316 ? 6.683   -18.883 -38.630 1.00 55.57  ? 316 PRO A CB  1 
ATOM   2538  C CG  . PRO A 1 316 ? 7.828   -17.976 -39.043 1.00 56.43  ? 316 PRO A CG  1 
ATOM   2539  C CD  . PRO A 1 316 ? 8.657   -18.791 -40.017 1.00 54.35  ? 316 PRO A CD  1 
ATOM   2540  N N   . GLY A 1 317 ? 4.086   -19.754 -40.650 1.00 46.46  ? 317 GLY A N   1 
ATOM   2541  C CA  . GLY A 1 317 ? 2.885   -19.279 -41.313 1.00 43.82  ? 317 GLY A CA  1 
ATOM   2542  C C   . GLY A 1 317 ? 2.624   -20.016 -42.616 1.00 45.64  ? 317 GLY A C   1 
ATOM   2543  O O   . GLY A 1 317 ? 1.677   -19.691 -43.328 1.00 41.52  ? 317 GLY A O   1 
ATOM   2544  N N   . TYR A 1 318 ? 3.516   -20.966 -42.940 1.00 51.10  ? 318 TYR A N   1 
ATOM   2545  C CA  . TYR A 1 318 ? 3.381   -21.816 -44.114 1.00 51.14  ? 318 TYR A CA  1 
ATOM   2546  C C   . TYR A 1 318 ? 3.281   -23.276 -43.653 1.00 54.82  ? 318 TYR A C   1 
ATOM   2547  O O   . TYR A 1 318 ? 3.836   -23.662 -42.615 1.00 55.39  ? 318 TYR A O   1 
ATOM   2548  C CB  . TYR A 1 318 ? 4.505   -21.484 -45.100 1.00 52.81  ? 318 TYR A CB  1 
ATOM   2549  C CG  . TYR A 1 318 ? 4.338   -20.124 -45.736 1.00 46.12  ? 318 TYR A CG  1 
ATOM   2550  C CD1 . TYR A 1 318 ? 4.570   -18.950 -45.025 1.00 49.41  ? 318 TYR A CD1 1 
ATOM   2551  C CD2 . TYR A 1 318 ? 3.874   -20.003 -47.035 1.00 43.03  ? 318 TYR A CD2 1 
ATOM   2552  C CE1 . TYR A 1 318 ? 4.375   -17.701 -45.606 1.00 46.64  ? 318 TYR A CE1 1 
ATOM   2553  C CE2 . TYR A 1 318 ? 3.672   -18.774 -47.631 1.00 43.37  ? 318 TYR A CE2 1 
ATOM   2554  C CZ  . TYR A 1 318 ? 3.925   -17.613 -46.914 1.00 44.63  ? 318 TYR A CZ  1 
ATOM   2555  O OH  . TYR A 1 318 ? 3.685   -16.404 -47.524 1.00 42.71  ? 318 TYR A OH  1 
ATOM   2556  N N   . GLY A 1 319 ? 2.475   -24.061 -44.375 1.00 53.55  ? 319 GLY A N   1 
ATOM   2557  C CA  . GLY A 1 319 ? 2.223   -25.455 -44.028 1.00 51.30  ? 319 GLY A CA  1 
ATOM   2558  C C   . GLY A 1 319 ? 1.013   -25.625 -43.113 1.00 53.92  ? 319 GLY A C   1 
ATOM   2559  O O   . GLY A 1 319 ? 0.620   -24.708 -42.382 1.00 49.80  ? 319 GLY A O   1 
ATOM   2560  N N   . HIS A 1 320 ? 0.438   -26.828 -43.152 1.00 52.12  ? 320 HIS A N   1 
ATOM   2561  C CA  . HIS A 1 320 ? -0.629  -27.198 -42.240 1.00 58.78  ? 320 HIS A CA  1 
ATOM   2562  C C   . HIS A 1 320 ? -0.659  -28.717 -42.068 1.00 60.65  ? 320 HIS A C   1 
ATOM   2563  O O   . HIS A 1 320 ? -0.270  -29.452 -42.972 1.00 52.28  ? 320 HIS A O   1 
ATOM   2564  C CB  . HIS A 1 320 ? -1.987  -26.715 -42.770 1.00 63.74  ? 320 HIS A CB  1 
ATOM   2565  C CG  . HIS A 1 320 ? -3.024  -26.494 -41.717 1.00 60.37  ? 320 HIS A CG  1 
ATOM   2566  N ND1 . HIS A 1 320 ? -4.027  -27.395 -41.430 1.00 59.71  ? 320 HIS A ND1 1 
ATOM   2567  C CD2 . HIS A 1 320 ? -3.205  -25.454 -40.874 1.00 63.42  ? 320 HIS A CD2 1 
ATOM   2568  C CE1 . HIS A 1 320 ? -4.783  -26.908 -40.444 1.00 61.31  ? 320 HIS A CE1 1 
ATOM   2569  N NE2 . HIS A 1 320 ? -4.308  -25.725 -40.099 1.00 55.56  ? 320 HIS A NE2 1 
ATOM   2570  N N   . ALA A 1 321 ? -1.198  -29.149 -40.920 1.00 60.79  ? 321 ALA A N   1 
ATOM   2571  C CA  . ALA A 1 321 ? -1.415  -30.549 -40.589 1.00 69.34  ? 321 ALA A CA  1 
ATOM   2572  C C   . ALA A 1 321 ? -2.484  -31.206 -41.468 1.00 72.27  ? 321 ALA A C   1 
ATOM   2573  O O   . ALA A 1 321 ? -2.645  -32.418 -41.357 1.00 76.78  ? 321 ALA A O   1 
ATOM   2574  C CB  . ALA A 1 321 ? -1.795  -30.674 -39.126 1.00 64.52  ? 321 ALA A CB  1 
ATOM   2575  N N   . VAL A 1 322 ? -3.207  -30.425 -42.287 1.00 75.81  ? 322 VAL A N   1 
ATOM   2576  C CA  . VAL A 1 322 ? -4.303  -30.981 -43.145 1.00 72.24  ? 322 VAL A CA  1 
ATOM   2577  C C   . VAL A 1 322 ? -4.448  -30.165 -44.434 1.00 71.38  ? 322 VAL A C   1 
ATOM   2578  O O   . VAL A 1 322 ? -4.519  -30.777 -45.509 1.00 57.62  ? 322 VAL A O   1 
ATOM   2579  C CB  . VAL A 1 322 ? -5.633  -31.065 -42.370 1.00 81.09  ? 322 VAL A CB  1 
ATOM   2580  C CG1 . VAL A 1 322 ? -5.691  -30.143 -41.165 1.00 83.65  ? 322 VAL A CG1 1 
ATOM   2581  C CG2 . VAL A 1 322 ? -6.854  -30.885 -43.259 1.00 85.95  ? 322 VAL A CG2 1 
ATOM   2582  N N   . LEU A 1 323 ? -4.501  -28.836 -44.323 1.00 72.60  ? 323 LEU A N   1 
ATOM   2583  C CA  . LEU A 1 323 ? -4.624  -27.958 -45.484 1.00 71.50  ? 323 LEU A CA  1 
ATOM   2584  C C   . LEU A 1 323 ? -3.562  -28.329 -46.512 1.00 64.99  ? 323 LEU A C   1 
ATOM   2585  O O   . LEU A 1 323 ? -2.467  -28.739 -46.116 1.00 60.94  ? 323 LEU A O   1 
ATOM   2586  C CB  . LEU A 1 323 ? -4.449  -26.482 -45.080 1.00 73.63  ? 323 LEU A CB  1 
ATOM   2587  C CG  . LEU A 1 323 ? -5.712  -25.627 -44.928 1.00 77.53  ? 323 LEU A CG  1 
ATOM   2588  C CD1 . LEU A 1 323 ? -6.765  -25.982 -45.969 1.00 72.65  ? 323 LEU A CD1 1 
ATOM   2589  C CD2 . LEU A 1 323 ? -6.284  -25.721 -43.520 1.00 85.19  ? 323 LEU A CD2 1 
ATOM   2590  N N   . ARG A 1 324 ? -3.907  -28.143 -47.800 1.00 59.54  ? 324 ARG A N   1 
ATOM   2591  C CA  . ARG A 1 324 ? -3.022  -28.488 -48.906 1.00 69.67  ? 324 ARG A CA  1 
ATOM   2592  C C   . ARG A 1 324 ? -2.966  -27.395 -49.971 1.00 63.66  ? 324 ARG A C   1 
ATOM   2593  O O   . ARG A 1 324 ? -2.194  -27.521 -50.913 1.00 71.10  ? 324 ARG A O   1 
ATOM   2594  C CB  . ARG A 1 324 ? -3.481  -29.805 -49.549 1.00 72.47  ? 324 ARG A CB  1 
ATOM   2595  C CG  . ARG A 1 324 ? -2.365  -30.718 -50.036 1.00 75.04  ? 324 ARG A CG  1 
ATOM   2596  C CD  . ARG A 1 324 ? -1.380  -31.197 -48.975 1.00 74.28  ? 324 ARG A CD  1 
ATOM   2597  N NE  . ARG A 1 324 ? -1.789  -30.992 -47.589 1.00 73.94  ? 324 ARG A NE  1 
ATOM   2598  C CZ  . ARG A 1 324 ? -1.306  -31.650 -46.539 1.00 75.26  ? 324 ARG A CZ  1 
ATOM   2599  N NH1 . ARG A 1 324 ? -1.217  -31.044 -45.362 1.00 72.88  ? 324 ARG A NH1 1 
ATOM   2600  N NH2 . ARG A 1 324 ? -0.808  -32.863 -46.698 1.00 64.52  ? 324 ARG A NH2 1 
ATOM   2601  N N   . VAL A 1 325 ? -3.742  -26.334 -49.783 1.00 70.01  ? 325 VAL A N   1 
ATOM   2602  C CA  . VAL A 1 325 ? -3.667  -25.159 -50.698 1.00 72.04  ? 325 VAL A CA  1 
ATOM   2603  C C   . VAL A 1 325 ? -3.673  -23.898 -49.825 1.00 72.18  ? 325 VAL A C   1 
ATOM   2604  O O   . VAL A 1 325 ? -3.487  -24.032 -48.605 1.00 73.34  ? 325 VAL A O   1 
ATOM   2605  C CB  . VAL A 1 325 ? -4.811  -25.153 -51.725 1.00 69.58  ? 325 VAL A CB  1 
ATOM   2606  C CG1 . VAL A 1 325 ? -4.636  -26.231 -52.782 1.00 70.30  ? 325 VAL A CG1 1 
ATOM   2607  C CG2 . VAL A 1 325 ? -6.164  -25.283 -51.046 1.00 75.79  ? 325 VAL A CG2 1 
ATOM   2608  N N   . THR A 1 326 ? -3.897  -22.728 -50.416 1.00 66.00  ? 326 THR A N   1 
ATOM   2609  C CA  . THR A 1 326 ? -3.876  -21.472 -49.674 1.00 64.67  ? 326 THR A CA  1 
ATOM   2610  C C   . THR A 1 326 ? -5.098  -21.403 -48.751 1.00 54.18  ? 326 THR A C   1 
ATOM   2611  O O   . THR A 1 326 ? -6.228  -21.677 -49.154 1.00 52.96  ? 326 THR A O   1 
ATOM   2612  C CB  . THR A 1 326 ? -3.716  -20.277 -50.626 1.00 60.76  ? 326 THR A CB  1 
ATOM   2613  O OG1 . THR A 1 326 ? -2.397  -20.384 -51.157 1.00 59.60  ? 326 THR A OG1 1 
ATOM   2614  C CG2 . THR A 1 326 ? -3.868  -18.927 -49.954 1.00 64.04  ? 326 THR A CG2 1 
ATOM   2615  N N   . ASP A 1 327 ? -4.844  -21.091 -47.479 1.00 49.17  ? 327 ASP A N   1 
ATOM   2616  C CA  . ASP A 1 327 ? -5.900  -21.042 -46.486 1.00 45.18  ? 327 ASP A CA  1 
ATOM   2617  C C   . ASP A 1 327 ? -6.808  -19.890 -46.895 1.00 37.87  ? 327 ASP A C   1 
ATOM   2618  O O   . ASP A 1 327 ? -6.379  -18.746 -46.988 1.00 45.57  ? 327 ASP A O   1 
ATOM   2619  C CB  . ASP A 1 327 ? -5.281  -20.950 -45.085 1.00 46.25  ? 327 ASP A CB  1 
ATOM   2620  C CG  . ASP A 1 327 ? -6.249  -21.054 -43.915 1.00 46.46  ? 327 ASP A CG  1 
ATOM   2621  O OD1 . ASP A 1 327 ? -7.470  -20.896 -44.135 1.00 45.09  ? 327 ASP A OD1 1 
ATOM   2622  O OD2 . ASP A 1 327 ? -5.764  -21.281 -42.779 1.00 47.40  ? 327 ASP A OD2 1 
ATOM   2623  N N   . PRO A 1 328 ? -8.090  -20.120 -47.209 1.00 42.78  ? 328 PRO A N   1 
ATOM   2624  C CA  . PRO A 1 328 ? -8.991  -18.996 -47.465 1.00 40.34  ? 328 PRO A CA  1 
ATOM   2625  C C   . PRO A 1 328 ? -9.139  -17.984 -46.307 1.00 42.13  ? 328 PRO A C   1 
ATOM   2626  O O   . PRO A 1 328 ? -9.600  -16.862 -46.499 1.00 43.47  ? 328 PRO A O   1 
ATOM   2627  C CB  . PRO A 1 328 ? -10.319 -19.700 -47.761 1.00 42.49  ? 328 PRO A CB  1 
ATOM   2628  C CG  . PRO A 1 328 ? -10.215 -21.038 -47.072 1.00 46.96  ? 328 PRO A CG  1 
ATOM   2629  C CD  . PRO A 1 328 ? -8.758  -21.428 -47.257 1.00 47.77  ? 328 PRO A CD  1 
ATOM   2630  N N   . ARG A 1 329 ? -8.740  -18.365 -45.091 1.00 43.45  ? 329 ARG A N   1 
ATOM   2631  C CA  . ARG A 1 329 ? -8.723  -17.424 -43.975 1.00 43.04  ? 329 ARG A CA  1 
ATOM   2632  C C   . ARG A 1 329 ? -7.573  -16.433 -44.170 1.00 47.52  ? 329 ARG A C   1 
ATOM   2633  O O   . ARG A 1 329 ? -7.683  -15.263 -43.780 1.00 41.87  ? 329 ARG A O   1 
ATOM   2634  C CB  . ARG A 1 329 ? -8.644  -18.180 -42.651 1.00 39.48  ? 329 ARG A CB  1 
ATOM   2635  C CG  . ARG A 1 329 ? -9.807  -19.145 -42.402 1.00 39.34  ? 329 ARG A CG  1 
ATOM   2636  C CD  . ARG A 1 329 ? -9.630  -20.023 -41.174 1.00 35.71  ? 329 ARG A CD  1 
ATOM   2637  N NE  . ARG A 1 329 ? -8.400  -20.799 -41.237 1.00 37.19  ? 329 ARG A NE  1 
ATOM   2638  C CZ  . ARG A 1 329 ? -7.922  -21.607 -40.296 1.00 39.57  ? 329 ARG A CZ  1 
ATOM   2639  N NH1 . ARG A 1 329 ? -8.539  -21.759 -39.131 1.00 40.90  ? 329 ARG A NH1 1 
ATOM   2640  N NH2 . ARG A 1 329 ? -6.801  -22.270 -40.527 1.00 43.72  ? 329 ARG A NH2 1 
ATOM   2641  N N   . TYR A 1 330 ? -6.478  -16.895 -44.801 1.00 45.10  ? 330 TYR A N   1 
ATOM   2642  C CA  . TYR A 1 330 ? -5.390  -15.999 -45.173 1.00 43.29  ? 330 TYR A CA  1 
ATOM   2643  C C   . TYR A 1 330 ? -5.899  -14.991 -46.196 1.00 39.26  ? 330 TYR A C   1 
ATOM   2644  O O   . TYR A 1 330 ? -5.624  -13.793 -46.089 1.00 40.83  ? 330 TYR A O   1 
ATOM   2645  C CB  . TYR A 1 330 ? -4.154  -16.754 -45.687 1.00 41.32  ? 330 TYR A CB  1 
ATOM   2646  C CG  . TYR A 1 330 ? -2.985  -15.898 -46.131 1.00 38.33  ? 330 TYR A CG  1 
ATOM   2647  C CD1 . TYR A 1 330 ? -2.950  -15.304 -47.380 1.00 41.58  ? 330 TYR A CD1 1 
ATOM   2648  C CD2 . TYR A 1 330 ? -1.912  -15.666 -45.283 1.00 38.51  ? 330 TYR A CD2 1 
ATOM   2649  C CE1 . TYR A 1 330 ? -1.861  -14.547 -47.799 1.00 43.00  ? 330 TYR A CE1 1 
ATOM   2650  C CE2 . TYR A 1 330 ? -0.814  -14.922 -45.686 1.00 40.37  ? 330 TYR A CE2 1 
ATOM   2651  C CZ  . TYR A 1 330 ? -0.778  -14.368 -46.957 1.00 39.11  ? 330 TYR A CZ  1 
ATOM   2652  O OH  . TYR A 1 330 ? 0.293   -13.577 -47.322 1.00 41.50  ? 330 TYR A OH  1 
ATOM   2653  N N   . VAL A 1 331 ? -6.630  -15.474 -47.199 1.00 43.30  ? 331 VAL A N   1 
ATOM   2654  C CA  . VAL A 1 331 ? -6.966  -14.612 -48.323 1.00 44.79  ? 331 VAL A CA  1 
ATOM   2655  C C   . VAL A 1 331 ? -7.903  -13.492 -47.860 1.00 40.73  ? 331 VAL A C   1 
ATOM   2656  O O   . VAL A 1 331 ? -7.847  -12.381 -48.378 1.00 40.54  ? 331 VAL A O   1 
ATOM   2657  C CB  . VAL A 1 331 ? -7.557  -15.422 -49.503 1.00 49.06  ? 331 VAL A CB  1 
ATOM   2658  C CG1 . VAL A 1 331 ? -8.082  -14.524 -50.609 1.00 44.84  ? 331 VAL A CG1 1 
ATOM   2659  C CG2 . VAL A 1 331 ? -6.538  -16.417 -50.054 1.00 52.06  ? 331 VAL A CG2 1 
ATOM   2660  N N   . ALA A 1 332 ? -8.792  -13.774 -46.898 1.00 41.66  ? 332 ALA A N   1 
ATOM   2661  C CA  . ALA A 1 332 ? -9.710  -12.743 -46.423 1.00 38.40  ? 332 ALA A CA  1 
ATOM   2662  C C   . ALA A 1 332 ? -8.940  -11.632 -45.705 1.00 37.21  ? 332 ALA A C   1 
ATOM   2663  O O   . ALA A 1 332 ? -9.250  -10.450 -45.830 1.00 38.75  ? 332 ALA A O   1 
ATOM   2664  C CB  . ALA A 1 332 ? -10.771 -13.359 -45.546 1.00 41.28  ? 332 ALA A CB  1 
ATOM   2665  N N   . GLN A 1 333 ? -7.902  -12.026 -44.972 1.00 37.98  ? 333 GLN A N   1 
ATOM   2666  C CA  . GLN A 1 333 ? -7.105  -11.084 -44.208 1.00 37.53  ? 333 GLN A CA  1 
ATOM   2667  C C   . GLN A 1 333 ? -6.268  -10.199 -45.140 1.00 41.43  ? 333 GLN A C   1 
ATOM   2668  O O   . GLN A 1 333 ? -6.151  -8.991  -44.922 1.00 40.75  ? 333 GLN A O   1 
ATOM   2669  C CB  . GLN A 1 333 ? -6.241  -11.870 -43.237 1.00 36.53  ? 333 GLN A CB  1 
ATOM   2670  C CG  . GLN A 1 333 ? -7.028  -12.467 -42.086 1.00 38.19  ? 333 GLN A CG  1 
ATOM   2671  C CD  . GLN A 1 333 ? -6.110  -13.160 -41.115 1.00 40.41  ? 333 GLN A CD  1 
ATOM   2672  O OE1 . GLN A 1 333 ? -5.795  -12.622 -40.070 1.00 44.25  ? 333 GLN A OE1 1 
ATOM   2673  N NE2 . GLN A 1 333 ? -5.647  -14.348 -41.462 1.00 41.46  ? 333 GLN A NE2 1 
ATOM   2674  N N   . ARG A 1 334 ? -5.712  -10.800 -46.195 1.00 41.31  ? 334 ARG A N   1 
ATOM   2675  C CA  . ARG A 1 334 ? -4.983  -10.058 -47.216 1.00 40.13  ? 334 ARG A CA  1 
ATOM   2676  C C   . ARG A 1 334 ? -5.884  -9.008  -47.861 1.00 36.62  ? 334 ARG A C   1 
ATOM   2677  O O   . ARG A 1 334 ? -5.490  -7.855  -48.078 1.00 42.83  ? 334 ARG A O   1 
ATOM   2678  C CB  . ARG A 1 334 ? -4.420  -11.028 -48.265 1.00 41.36  ? 334 ARG A CB  1 
ATOM   2679  C CG  . ARG A 1 334 ? -3.859  -10.350 -49.510 1.00 43.68  ? 334 ARG A CG  1 
ATOM   2680  C CD  . ARG A 1 334 ? -3.172  -11.333 -50.456 1.00 48.82  ? 334 ARG A CD  1 
ATOM   2681  N NE  . ARG A 1 334 ? -2.623  -10.669 -51.630 1.00 54.66  ? 334 ARG A NE  1 
ATOM   2682  C CZ  . ARG A 1 334 ? -1.511  -9.938  -51.653 1.00 55.14  ? 334 ARG A CZ  1 
ATOM   2683  N NH1 . ARG A 1 334 ? -0.675  -9.939  -50.628 1.00 48.31  ? 334 ARG A NH1 1 
ATOM   2684  N NH2 . ARG A 1 334 ? -1.225  -9.230  -52.730 1.00 59.31  ? 334 ARG A NH2 1 
ATOM   2685  N N   . ASP A 1 335 ? -7.117  -9.399  -48.155 1.00 38.40  ? 335 ASP A N   1 
ATOM   2686  C CA  . ASP A 1 335 ? -8.082  -8.468  -48.725 1.00 42.83  ? 335 ASP A CA  1 
ATOM   2687  C C   . ASP A 1 335 ? -8.317  -7.271  -47.800 1.00 45.26  ? 335 ASP A C   1 
ATOM   2688  O O   . ASP A 1 335 ? -8.304  -6.120  -48.244 1.00 43.13  ? 335 ASP A O   1 
ATOM   2689  C CB  . ASP A 1 335 ? -9.383  -9.203  -49.039 1.00 43.17  ? 335 ASP A CB  1 
ATOM   2690  C CG  . ASP A 1 335 ? -10.407 -8.331  -49.734 1.00 49.45  ? 335 ASP A CG  1 
ATOM   2691  O OD1 . ASP A 1 335 ? -10.145 -7.919  -50.898 1.00 51.40  ? 335 ASP A OD1 1 
ATOM   2692  O OD2 . ASP A 1 335 ? -11.464 -8.062  -49.108 1.00 51.13  ? 335 ASP A OD2 1 
ATOM   2693  N N   . PHE A 1 336 ? -8.551  -7.548  -46.505 1.00 41.99  ? 336 PHE A N   1 
ATOM   2694  C CA  . PHE A 1 336 ? -8.727  -6.499  -45.515 1.00 38.77  ? 336 PHE A CA  1 
ATOM   2695  C C   . PHE A 1 336 ? -7.516  -5.566  -45.551 1.00 34.82  ? 336 PHE A C   1 
ATOM   2696  O O   . PHE A 1 336 ? -7.680  -4.361  -45.484 1.00 39.34  ? 336 PHE A O   1 
ATOM   2697  C CB  . PHE A 1 336 ? -8.934  -7.099  -44.114 1.00 40.51  ? 336 PHE A CB  1 
ATOM   2698  C CG  . PHE A 1 336 ? -9.246  -6.093  -43.036 1.00 36.17  ? 336 PHE A CG  1 
ATOM   2699  C CD1 . PHE A 1 336 ? -8.250  -5.328  -42.459 1.00 37.69  ? 336 PHE A CD1 1 
ATOM   2700  C CD2 . PHE A 1 336 ? -10.547 -5.890  -42.626 1.00 37.83  ? 336 PHE A CD2 1 
ATOM   2701  C CE1 . PHE A 1 336 ? -8.558  -4.381  -41.498 1.00 38.08  ? 336 PHE A CE1 1 
ATOM   2702  C CE2 . PHE A 1 336 ? -10.856 -4.938  -41.667 1.00 37.92  ? 336 PHE A CE2 1 
ATOM   2703  C CZ  . PHE A 1 336 ? -9.855  -4.188  -41.101 1.00 39.13  ? 336 PHE A CZ  1 
ATOM   2704  N N   . ALA A 1 337 ? -6.301  -6.128  -45.622 1.00 38.10  ? 337 ALA A N   1 
ATOM   2705  C CA  . ALA A 1 337 ? -5.069  -5.351  -45.572 1.00 41.03  ? 337 ALA A CA  1 
ATOM   2706  C C   . ALA A 1 337 ? -4.889  -4.474  -46.825 1.00 45.78  ? 337 ALA A C   1 
ATOM   2707  O O   . ALA A 1 337 ? -4.497  -3.299  -46.727 1.00 43.71  ? 337 ALA A O   1 
ATOM   2708  C CB  . ALA A 1 337 ? -3.915  -6.306  -45.415 1.00 42.02  ? 337 ALA A CB  1 
ATOM   2709  N N   . LEU A 1 338 ? -5.146  -5.052  -48.011 1.00 42.99  ? 338 LEU A N   1 
ATOM   2710  C CA  . LEU A 1 338 ? -5.053  -4.300  -49.262 1.00 52.12  ? 338 LEU A CA  1 
ATOM   2711  C C   . LEU A 1 338 ? -6.008  -3.113  -49.217 1.00 50.72  ? 338 LEU A C   1 
ATOM   2712  O O   . LEU A 1 338 ? -5.683  -2.026  -49.667 1.00 49.79  ? 338 LEU A O   1 
ATOM   2713  C CB  . LEU A 1 338 ? -5.409  -5.196  -50.454 1.00 49.38  ? 338 LEU A CB  1 
ATOM   2714  C CG  . LEU A 1 338 ? -4.386  -6.264  -50.825 1.00 49.37  ? 338 LEU A CG  1 
ATOM   2715  C CD1 . LEU A 1 338 ? -4.993  -7.216  -51.840 1.00 51.78  ? 338 LEU A CD1 1 
ATOM   2716  C CD2 . LEU A 1 338 ? -3.093  -5.649  -51.365 1.00 48.15  ? 338 LEU A CD2 1 
ATOM   2717  N N   . LYS A 1 339 ? -7.181  -3.338  -48.628 1.00 51.70  ? 339 LYS A N   1 
ATOM   2718  C CA  . LYS A 1 339 ? -8.212  -2.319  -48.515 1.00 48.47  ? 339 LYS A CA  1 
ATOM   2719  C C   . LYS A 1 339 ? -7.815  -1.254  -47.494 1.00 50.78  ? 339 LYS A C   1 
ATOM   2720  O O   . LYS A 1 339 ? -8.050  -0.069  -47.716 1.00 44.09  ? 339 LYS A O   1 
ATOM   2721  C CB  . LYS A 1 339 ? -9.497  -3.063  -48.130 1.00 60.54  ? 339 LYS A CB  1 
ATOM   2722  C CG  . LYS A 1 339 ? -10.827 -2.371  -48.376 1.00 73.86  ? 339 LYS A CG  1 
ATOM   2723  C CD  . LYS A 1 339 ? -11.990 -3.361  -48.340 1.00 80.76  ? 339 LYS A CD  1 
ATOM   2724  C CE  . LYS A 1 339 ? -13.339 -2.686  -48.207 1.00 81.97  ? 339 LYS A CE  1 
ATOM   2725  N NZ  . LYS A 1 339 ? -14.404 -3.667  -47.904 1.00 83.08  ? 339 LYS A NZ  1 
ATOM   2726  N N   . HIS A 1 340 ? -7.244  -1.656  -46.340 1.00 47.38  ? 340 HIS A N   1 
ATOM   2727  C CA  . HIS A 1 340 ? -7.209  -0.743  -45.203 1.00 46.23  ? 340 HIS A CA  1 
ATOM   2728  C C   . HIS A 1 340 ? -5.804  -0.325  -44.802 1.00 39.13  ? 340 HIS A C   1 
ATOM   2729  O O   . HIS A 1 340 ? -5.682  0.675   -44.148 1.00 42.61  ? 340 HIS A O   1 
ATOM   2730  C CB  . HIS A 1 340 ? -7.914  -1.321  -43.976 1.00 49.23  ? 340 HIS A CB  1 
ATOM   2731  C CG  . HIS A 1 340 ? -9.345  -1.583  -44.239 1.00 47.14  ? 340 HIS A CG  1 
ATOM   2732  N ND1 . HIS A 1 340 ? -10.212 -0.564  -44.532 1.00 47.44  ? 340 HIS A ND1 1 
ATOM   2733  C CD2 . HIS A 1 340 ? -10.059 -2.707  -44.264 1.00 48.33  ? 340 HIS A CD2 1 
ATOM   2734  C CE1 . HIS A 1 340 ? -11.423 -1.066  -44.727 1.00 48.99  ? 340 HIS A CE1 1 
ATOM   2735  N NE2 . HIS A 1 340 ? -11.353 -2.374  -44.564 1.00 54.30  ? 340 HIS A NE2 1 
ATOM   2736  N N   . LEU A 1 341 ? -4.751  -1.100  -45.082 1.00 43.79  ? 341 LEU A N   1 
ATOM   2737  C CA  . LEU A 1 341 ? -3.424  -0.643  -44.707 1.00 42.93  ? 341 LEU A CA  1 
ATOM   2738  C C   . LEU A 1 341 ? -2.398  -1.072  -45.745 1.00 46.61  ? 341 LEU A C   1 
ATOM   2739  O O   . LEU A 1 341 ? -1.375  -1.657  -45.400 1.00 38.32  ? 341 LEU A O   1 
ATOM   2740  C CB  . LEU A 1 341 ? -3.094  -1.195  -43.317 1.00 45.36  ? 341 LEU A CB  1 
ATOM   2741  C CG  . LEU A 1 341 ? -3.302  -2.696  -43.146 1.00 42.19  ? 341 LEU A CG  1 
ATOM   2742  C CD1 . LEU A 1 341 ? -2.047  -3.382  -42.632 1.00 39.70  ? 341 LEU A CD1 1 
ATOM   2743  C CD2 . LEU A 1 341 ? -4.492  -2.953  -42.246 1.00 45.70  ? 341 LEU A CD2 1 
ATOM   2744  N N   . PRO A 1 342 ? -2.590  -0.712  -47.034 1.00 50.92  ? 342 PRO A N   1 
ATOM   2745  C CA  . PRO A 1 342 ? -1.711  -1.198  -48.103 1.00 48.70  ? 342 PRO A CA  1 
ATOM   2746  C C   . PRO A 1 342 ? -0.259  -0.731  -47.973 1.00 46.84  ? 342 PRO A C   1 
ATOM   2747  O O   . PRO A 1 342 ? 0.659   -1.441  -48.391 1.00 52.28  ? 342 PRO A O   1 
ATOM   2748  C CB  . PRO A 1 342 ? -2.371  -0.670  -49.393 1.00 54.08  ? 342 PRO A CB  1 
ATOM   2749  C CG  . PRO A 1 342 ? -3.188  0.531   -48.943 1.00 48.43  ? 342 PRO A CG  1 
ATOM   2750  C CD  . PRO A 1 342 ? -3.622  0.218   -47.521 1.00 54.00  ? 342 PRO A CD  1 
ATOM   2751  N N   . ASP A 1 343 ? -0.040  0.413   -47.318 1.00 48.75  ? 343 ASP A N   1 
ATOM   2752  C CA  . ASP A 1 343 ? 1.304   0.974   -47.201 1.00 58.24  ? 343 ASP A CA  1 
ATOM   2753  C C   . ASP A 1 343 ? 2.007   0.586   -45.898 1.00 54.45  ? 343 ASP A C   1 
ATOM   2754  O O   . ASP A 1 343 ? 3.131   1.029   -45.658 1.00 52.84  ? 343 ASP A O   1 
ATOM   2755  C CB  . ASP A 1 343 ? 1.243   2.490   -47.382 1.00 60.30  ? 343 ASP A CB  1 
ATOM   2756  C CG  . ASP A 1 343 ? 0.632   2.817   -48.736 1.00 67.90  ? 343 ASP A CG  1 
ATOM   2757  O OD1 . ASP A 1 343 ? 1.164   2.302   -49.721 1.00 65.26  ? 343 ASP A OD1 1 
ATOM   2758  O OD2 . ASP A 1 343 ? -0.411  3.516   -48.786 1.00 82.41  ? 343 ASP A OD2 1 
ATOM   2759  N N   . ASP A 1 344 ? 1.365   -0.235  -45.059 1.00 51.66  ? 344 ASP A N   1 
ATOM   2760  C CA  . ASP A 1 344 ? 1.990   -0.685  -43.824 1.00 47.24  ? 344 ASP A CA  1 
ATOM   2761  C C   . ASP A 1 344 ? 3.190   -1.544  -44.212 1.00 46.47  ? 344 ASP A C   1 
ATOM   2762  O O   . ASP A 1 344 ? 3.071   -2.507  -44.973 1.00 47.08  ? 344 ASP A O   1 
ATOM   2763  C CB  . ASP A 1 344 ? 0.980   -1.416  -42.932 1.00 50.79  ? 344 ASP A CB  1 
ATOM   2764  C CG  . ASP A 1 344 ? 1.547   -1.945  -41.621 1.00 49.44  ? 344 ASP A CG  1 
ATOM   2765  O OD1 . ASP A 1 344 ? 2.206   -3.014  -41.657 1.00 48.94  ? 344 ASP A OD1 1 
ATOM   2766  O OD2 . ASP A 1 344 ? 1.360   -1.262  -40.577 1.00 45.91  ? 344 ASP A OD2 1 
ATOM   2767  N N   . GLU A 1 345 ? 4.354   -1.134  -43.724 1.00 43.60  ? 345 GLU A N   1 
ATOM   2768  C CA  . GLU A 1 345 ? 5.624   -1.772  -44.038 1.00 48.22  ? 345 GLU A CA  1 
ATOM   2769  C C   . GLU A 1 345 ? 5.639   -3.274  -43.724 1.00 47.25  ? 345 GLU A C   1 
ATOM   2770  O O   . GLU A 1 345 ? 6.104   -4.082  -44.530 1.00 49.05  ? 345 GLU A O   1 
ATOM   2771  C CB  . GLU A 1 345 ? 6.705   -1.066  -43.232 1.00 51.66  ? 345 GLU A CB  1 
ATOM   2772  C CG  . GLU A 1 345 ? 6.969   0.357   -43.704 1.00 63.43  ? 345 GLU A CG  1 
ATOM   2773  C CD  . GLU A 1 345 ? 7.920   0.450   -44.890 1.00 73.71  ? 345 GLU A CD  1 
ATOM   2774  O OE1 . GLU A 1 345 ? 7.477   0.223   -46.043 1.00 83.90  ? 345 GLU A OE1 1 
ATOM   2775  O OE2 . GLU A 1 345 ? 9.115   0.706   -44.652 1.00 70.33  ? 345 GLU A OE2 1 
ATOM   2776  N N   . LEU A 1 346 ? 5.176   -3.648  -42.532 1.00 37.26  ? 346 LEU A N   1 
ATOM   2777  C CA  . LEU A 1 346 ? 5.142   -5.035  -42.121 1.00 38.44  ? 346 LEU A CA  1 
ATOM   2778  C C   . LEU A 1 346 ? 4.202   -5.814  -43.050 1.00 37.46  ? 346 LEU A C   1 
ATOM   2779  O O   . LEU A 1 346 ? 4.525   -6.911  -43.506 1.00 36.86  ? 346 LEU A O   1 
ATOM   2780  C CB  . LEU A 1 346 ? 4.692   -5.110  -40.657 1.00 38.48  ? 346 LEU A CB  1 
ATOM   2781  C CG  . LEU A 1 346 ? 5.635   -4.524  -39.609 1.00 37.89  ? 346 LEU A CG  1 
ATOM   2782  C CD1 . LEU A 1 346 ? 5.206   -5.006  -38.231 1.00 40.16  ? 346 LEU A CD1 1 
ATOM   2783  C CD2 . LEU A 1 346 ? 7.089   -4.919  -39.868 1.00 41.85  ? 346 LEU A CD2 1 
ATOM   2784  N N   . PHE A 1 347 ? 3.058   -5.225  -43.392 1.00 38.20  ? 347 PHE A N   1 
ATOM   2785  C CA  . PHE A 1 347 ? 2.184   -5.850  -44.362 1.00 39.37  ? 347 PHE A CA  1 
ATOM   2786  C C   . PHE A 1 347 ? 2.896   -6.069  -45.710 1.00 46.96  ? 347 PHE A C   1 
ATOM   2787  O O   . PHE A 1 347 ? 2.680   -7.099  -46.356 1.00 42.81  ? 347 PHE A O   1 
ATOM   2788  C CB  . PHE A 1 347 ? 0.895   -5.057  -44.554 1.00 42.02  ? 347 PHE A CB  1 
ATOM   2789  C CG  . PHE A 1 347 ? 0.115   -5.558  -45.742 1.00 40.07  ? 347 PHE A CG  1 
ATOM   2790  C CD1 . PHE A 1 347 ? -0.197  -6.901  -45.853 1.00 42.88  ? 347 PHE A CD1 1 
ATOM   2791  C CD2 . PHE A 1 347 ? -0.189  -4.718  -46.797 1.00 44.58  ? 347 PHE A CD2 1 
ATOM   2792  C CE1 . PHE A 1 347 ? -0.875  -7.381  -46.964 1.00 44.89  ? 347 PHE A CE1 1 
ATOM   2793  C CE2 . PHE A 1 347 ? -0.869  -5.194  -47.903 1.00 42.56  ? 347 PHE A CE2 1 
ATOM   2794  C CZ  . PHE A 1 347 ? -1.208  -6.524  -47.983 1.00 44.02  ? 347 PHE A CZ  1 
ATOM   2795  N N   . LYS A 1 348 ? 3.741   -5.118  -46.136 1.00 42.37  ? 348 LYS A N   1 
ATOM   2796  C CA  . LYS A 1 348 ? 4.472   -5.263  -47.391 1.00 48.34  ? 348 LYS A CA  1 
ATOM   2797  C C   . LYS A 1 348 ? 5.417   -6.462  -47.344 1.00 45.16  ? 348 LYS A C   1 
ATOM   2798  O O   . LYS A 1 348 ? 5.620   -7.114  -48.357 1.00 53.08  ? 348 LYS A O   1 
ATOM   2799  C CB  . LYS A 1 348 ? 5.235   -3.981  -47.724 1.00 54.11  ? 348 LYS A CB  1 
ATOM   2800  C CG  . LYS A 1 348 ? 4.337   -2.842  -48.170 1.00 64.91  ? 348 LYS A CG  1 
ATOM   2801  C CD  . LYS A 1 348 ? 5.082   -1.607  -48.615 1.00 76.95  ? 348 LYS A CD  1 
ATOM   2802  C CE  . LYS A 1 348 ? 4.172   -0.622  -49.318 1.00 87.05  ? 348 LYS A CE  1 
ATOM   2803  N NZ  . LYS A 1 348 ? 4.673   0.769   -49.201 1.00 95.24  ? 348 LYS A NZ  1 
ATOM   2804  N N   . ILE A 1 349 ? 5.962   -6.796  -46.172 1.00 37.10  ? 349 ILE A N   1 
ATOM   2805  C CA  . ILE A 1 349 ? 6.784   -7.990  -46.081 1.00 40.68  ? 349 ILE A CA  1 
ATOM   2806  C C   . ILE A 1 349 ? 5.914   -9.241  -46.238 1.00 44.92  ? 349 ILE A C   1 
ATOM   2807  O O   . ILE A 1 349 ? 6.278   -10.155 -46.984 1.00 44.43  ? 349 ILE A O   1 
ATOM   2808  C CB  . ILE A 1 349 ? 7.642   -7.952  -44.803 1.00 38.70  ? 349 ILE A CB  1 
ATOM   2809  C CG1 . ILE A 1 349 ? 8.592   -6.756  -44.857 1.00 39.85  ? 349 ILE A CG1 1 
ATOM   2810  C CG2 . ILE A 1 349 ? 8.394   -9.257  -44.600 1.00 44.05  ? 349 ILE A CG2 1 
ATOM   2811  C CD1 . ILE A 1 349 ? 9.495   -6.618  -43.642 1.00 42.37  ? 349 ILE A CD1 1 
ATOM   2812  N N   . VAL A 1 350 ? 4.747   -9.261  -45.567 1.00 46.45  ? 350 VAL A N   1 
ATOM   2813  C CA  . VAL A 1 350 ? 3.827   -10.401 -45.578 1.00 38.41  ? 350 VAL A CA  1 
ATOM   2814  C C   . VAL A 1 350 ? 3.415   -10.714 -47.020 1.00 43.85  ? 350 VAL A C   1 
ATOM   2815  O O   . VAL A 1 350 ? 3.361   -11.874 -47.420 1.00 43.31  ? 350 VAL A O   1 
ATOM   2816  C CB  . VAL A 1 350 ? 2.602   -10.092 -44.685 1.00 38.10  ? 350 VAL A CB  1 
ATOM   2817  C CG1 . VAL A 1 350 ? 1.338   -10.863 -45.046 1.00 36.79  ? 350 VAL A CG1 1 
ATOM   2818  C CG2 . VAL A 1 350 ? 2.945   -10.310 -43.217 1.00 38.52  ? 350 VAL A CG2 1 
ATOM   2819  N N   . SER A 1 351 ? 3.065   -9.654  -47.747 1.00 46.18  ? 351 SER A N   1 
ATOM   2820  C CA  . SER A 1 351 ? 2.666   -9.693  -49.144 1.00 52.57  ? 351 SER A CA  1 
ATOM   2821  C C   . SER A 1 351 ? 3.786   -10.322 -49.987 1.00 47.53  ? 351 SER A C   1 
ATOM   2822  O O   . SER A 1 351 ? 3.594   -11.309 -50.686 1.00 53.83  ? 351 SER A O   1 
ATOM   2823  C CB  . SER A 1 351 ? 2.319   -8.279  -49.569 1.00 47.29  ? 351 SER A CB  1 
ATOM   2824  O OG  . SER A 1 351 ? 1.412   -8.263  -50.657 1.00 52.97  ? 351 SER A OG  1 
ATOM   2825  N N   . LEU A 1 352 ? 4.996   -9.802  -49.828 1.00 53.02  ? 352 LEU A N   1 
ATOM   2826  C CA  . LEU A 1 352 ? 6.147   -10.290 -50.562 1.00 54.78  ? 352 LEU A CA  1 
ATOM   2827  C C   . LEU A 1 352 ? 6.402   -11.765 -50.266 1.00 54.24  ? 352 LEU A C   1 
ATOM   2828  O O   . LEU A 1 352 ? 6.739   -12.529 -51.166 1.00 50.76  ? 352 LEU A O   1 
ATOM   2829  C CB  . LEU A 1 352 ? 7.362   -9.438  -50.193 1.00 57.54  ? 352 LEU A CB  1 
ATOM   2830  C CG  . LEU A 1 352 ? 8.554   -9.590  -51.136 1.00 64.91  ? 352 LEU A CG  1 
ATOM   2831  C CD1 . LEU A 1 352 ? 8.269   -8.928  -52.480 1.00 63.64  ? 352 LEU A CD1 1 
ATOM   2832  C CD2 . LEU A 1 352 ? 9.816   -9.021  -50.511 1.00 66.35  ? 352 LEU A CD2 1 
ATOM   2833  N N   . CYS A 1 353 ? 6.235   -12.174 -49.006 1.00 49.58  ? 353 CYS A N   1 
ATOM   2834  C CA  . CYS A 1 353 ? 6.340   -13.581 -48.666 1.00 48.89  ? 353 CYS A CA  1 
ATOM   2835  C C   . CYS A 1 353 ? 5.368   -14.410 -49.500 1.00 49.22  ? 353 CYS A C   1 
ATOM   2836  O O   . CYS A 1 353 ? 5.678   -15.550 -49.862 1.00 48.64  ? 353 CYS A O   1 
ATOM   2837  C CB  . CYS A 1 353 ? 6.063   -13.814 -47.184 1.00 50.91  ? 353 CYS A CB  1 
ATOM   2838  S SG  . CYS A 1 353 ? 7.453   -13.366 -46.119 1.00 52.51  ? 353 CYS A SG  1 
ATOM   2839  N N   . TYR A 1 354 ? 4.185   -13.836 -49.755 1.00 45.93  ? 354 TYR A N   1 
ATOM   2840  C CA  . TYR A 1 354 ? 3.136   -14.520 -50.494 1.00 51.95  ? 354 TYR A CA  1 
ATOM   2841  C C   . TYR A 1 354 ? 3.626   -14.845 -51.906 1.00 55.80  ? 354 TYR A C   1 
ATOM   2842  O O   . TYR A 1 354 ? 3.291   -15.895 -52.436 1.00 48.63  ? 354 TYR A O   1 
ATOM   2843  C CB  . TYR A 1 354 ? 1.849   -13.684 -50.537 1.00 43.90  ? 354 TYR A CB  1 
ATOM   2844  C CG  . TYR A 1 354 ? 0.589   -14.411 -50.952 1.00 41.52  ? 354 TYR A CG  1 
ATOM   2845  C CD1 . TYR A 1 354 ? 0.470   -15.781 -50.820 1.00 42.17  ? 354 TYR A CD1 1 
ATOM   2846  C CD2 . TYR A 1 354 ? -0.470  -13.722 -51.518 1.00 39.95  ? 354 TYR A CD2 1 
ATOM   2847  C CE1 . TYR A 1 354 ? -0.685  -16.444 -51.195 1.00 50.61  ? 354 TYR A CE1 1 
ATOM   2848  C CE2 . TYR A 1 354 ? -1.635  -14.364 -51.905 1.00 46.30  ? 354 TYR A CE2 1 
ATOM   2849  C CZ  . TYR A 1 354 ? -1.742  -15.734 -51.729 1.00 47.51  ? 354 TYR A CZ  1 
ATOM   2850  O OH  . TYR A 1 354 ? -2.854  -16.439 -52.095 1.00 52.16  ? 354 TYR A OH  1 
ATOM   2851  N N   . GLU A 1 355 ? 4.453   -13.970 -52.492 1.00 59.95  ? 355 GLU A N   1 
ATOM   2852  C CA  . GLU A 1 355 ? 4.981   -14.192 -53.836 1.00 63.02  ? 355 GLU A CA  1 
ATOM   2853  C C   . GLU A 1 355 ? 6.128   -15.208 -53.825 1.00 61.13  ? 355 GLU A C   1 
ATOM   2854  O O   . GLU A 1 355 ? 6.188   -16.089 -54.672 1.00 61.22  ? 355 GLU A O   1 
ATOM   2855  C CB  . GLU A 1 355 ? 5.489   -12.880 -54.430 1.00 69.37  ? 355 GLU A CB  1 
ATOM   2856  C CG  . GLU A 1 355 ? 4.409   -11.831 -54.605 1.00 76.09  ? 355 GLU A CG  1 
ATOM   2857  C CD  . GLU A 1 355 ? 4.940   -10.420 -54.820 1.00 86.39  ? 355 GLU A CD  1 
ATOM   2858  O OE1 . GLU A 1 355 ? 4.121   -9.478  -54.837 1.00 84.49  ? 355 GLU A OE1 1 
ATOM   2859  O OE2 . GLU A 1 355 ? 6.175   -10.263 -54.959 1.00 93.92  ? 355 GLU A OE2 1 
ATOM   2860  N N   . VAL A 1 356 ? 7.028   -15.102 -52.848 1.00 57.14  ? 356 VAL A N   1 
ATOM   2861  C CA  . VAL A 1 356 ? 8.313   -15.775 -52.909 1.00 58.45  ? 356 VAL A CA  1 
ATOM   2862  C C   . VAL A 1 356 ? 8.235   -17.143 -52.224 1.00 64.15  ? 356 VAL A C   1 
ATOM   2863  O O   . VAL A 1 356 ? 8.678   -18.138 -52.789 1.00 66.09  ? 356 VAL A O   1 
ATOM   2864  C CB  . VAL A 1 356 ? 9.407   -14.869 -52.301 1.00 55.65  ? 356 VAL A CB  1 
ATOM   2865  C CG1 . VAL A 1 356 ? 10.749  -15.569 -52.191 1.00 55.90  ? 356 VAL A CG1 1 
ATOM   2866  C CG2 . VAL A 1 356 ? 9.557   -13.554 -53.054 1.00 51.45  ? 356 VAL A CG2 1 
ATOM   2867  N N   . ILE A 1 357 ? 7.663   -17.208 -51.013 1.00 59.86  ? 357 ILE A N   1 
ATOM   2868  C CA  . ILE A 1 357 ? 7.908   -18.343 -50.136 1.00 58.11  ? 357 ILE A CA  1 
ATOM   2869  C C   . ILE A 1 357 ? 7.356   -19.648 -50.713 1.00 62.85  ? 357 ILE A C   1 
ATOM   2870  O O   . ILE A 1 357 ? 7.984   -20.691 -50.501 1.00 50.78  ? 357 ILE A O   1 
ATOM   2871  C CB  . ILE A 1 357 ? 7.384   -18.153 -48.696 1.00 52.41  ? 357 ILE A CB  1 
ATOM   2872  C CG1 . ILE A 1 357 ? 7.991   -16.945 -47.980 1.00 49.65  ? 357 ILE A CG1 1 
ATOM   2873  C CG2 . ILE A 1 357 ? 7.631   -19.429 -47.898 1.00 49.45  ? 357 ILE A CG2 1 
ATOM   2874  C CD1 . ILE A 1 357 ? 9.465   -17.059 -47.744 1.00 49.12  ? 357 ILE A CD1 1 
ATOM   2875  N N   . PRO A 1 358 ? 6.165   -19.685 -51.360 1.00 60.46  ? 358 PRO A N   1 
ATOM   2876  C CA  . PRO A 1 358 ? 5.634   -20.954 -51.872 1.00 70.24  ? 358 PRO A CA  1 
ATOM   2877  C C   . PRO A 1 358 ? 6.623   -21.684 -52.802 1.00 70.32  ? 358 PRO A C   1 
ATOM   2878  O O   . PRO A 1 358 ? 6.986   -22.833 -52.531 1.00 60.49  ? 358 PRO A O   1 
ATOM   2879  C CB  . PRO A 1 358 ? 4.324   -20.552 -52.581 1.00 69.58  ? 358 PRO A CB  1 
ATOM   2880  C CG  . PRO A 1 358 ? 3.965   -19.189 -52.004 1.00 68.22  ? 358 PRO A CG  1 
ATOM   2881  C CD  . PRO A 1 358 ? 5.284   -18.542 -51.651 1.00 63.13  ? 358 PRO A CD  1 
ATOM   2882  N N   . GLU A 1 359 ? 7.085   -20.987 -53.860 1.00 73.54  ? 359 GLU A N   1 
ATOM   2883  C CA  . GLU A 1 359 ? 8.085   -21.475 -54.810 1.00 76.35  ? 359 GLU A CA  1 
ATOM   2884  C C   . GLU A 1 359 ? 9.229   -22.192 -54.099 1.00 69.85  ? 359 GLU A C   1 
ATOM   2885  O O   . GLU A 1 359 ? 9.652   -23.264 -54.512 1.00 73.54  ? 359 GLU A O   1 
ATOM   2886  C CB  . GLU A 1 359 ? 8.723   -20.317 -55.584 1.00 77.82  ? 359 GLU A CB  1 
ATOM   2887  C CG  . GLU A 1 359 ? 7.816   -19.668 -56.623 1.00 85.98  ? 359 GLU A CG  1 
ATOM   2888  C CD  . GLU A 1 359 ? 8.114   -18.199 -56.902 1.00 83.85  ? 359 GLU A CD  1 
ATOM   2889  O OE1 . GLU A 1 359 ? 9.200   -17.732 -56.517 1.00 98.30  ? 359 GLU A OE1 1 
ATOM   2890  O OE2 . GLU A 1 359 ? 7.247   -17.509 -57.470 1.00 89.32  ? 359 GLU A OE2 1 
ATOM   2891  N N   . VAL A 1 360 ? 9.738   -21.567 -53.040 1.00 61.40  ? 360 VAL A N   1 
ATOM   2892  C CA  . VAL A 1 360 ? 10.879  -22.076 -52.300 1.00 61.17  ? 360 VAL A CA  1 
ATOM   2893  C C   . VAL A 1 360 ? 10.527  -23.391 -51.590 1.00 72.71  ? 360 VAL A C   1 
ATOM   2894  O O   . VAL A 1 360 ? 11.263  -24.375 -51.702 1.00 77.97  ? 360 VAL A O   1 
ATOM   2895  C CB  . VAL A 1 360 ? 11.384  -20.990 -51.329 1.00 55.97  ? 360 VAL A CB  1 
ATOM   2896  C CG1 . VAL A 1 360 ? 12.410  -21.517 -50.331 1.00 58.80  ? 360 VAL A CG1 1 
ATOM   2897  C CG2 . VAL A 1 360 ? 11.935  -19.797 -52.100 1.00 59.17  ? 360 VAL A CG2 1 
ATOM   2898  N N   . LEU A 1 361 ? 9.401   -23.410 -50.861 1.00 78.00  ? 361 LEU A N   1 
ATOM   2899  C CA  . LEU A 1 361 ? 9.007   -24.564 -50.060 1.00 73.93  ? 361 LEU A CA  1 
ATOM   2900  C C   . LEU A 1 361 ? 8.679   -25.772 -50.946 1.00 71.84  ? 361 LEU A C   1 
ATOM   2901  O O   . LEU A 1 361 ? 8.811   -26.908 -50.491 1.00 57.68  ? 361 LEU A O   1 
ATOM   2902  C CB  . LEU A 1 361 ? 7.802   -24.179 -49.191 1.00 75.22  ? 361 LEU A CB  1 
ATOM   2903  C CG  . LEU A 1 361 ? 8.106   -23.325 -47.960 1.00 75.95  ? 361 LEU A CG  1 
ATOM   2904  C CD1 . LEU A 1 361 ? 6.820   -22.815 -47.327 1.00 74.23  ? 361 LEU A CD1 1 
ATOM   2905  C CD2 . LEU A 1 361 ? 8.911   -24.110 -46.934 1.00 76.51  ? 361 LEU A CD2 1 
ATOM   2906  N N   . LYS A 1 362 ? 8.208   -25.514 -52.181 1.00 71.11  ? 362 LYS A N   1 
ATOM   2907  C CA  . LYS A 1 362 ? 7.973   -26.551 -53.179 1.00 75.35  ? 362 LYS A CA  1 
ATOM   2908  C C   . LYS A 1 362 ? 9.277   -27.252 -53.558 1.00 72.73  ? 362 LYS A C   1 
ATOM   2909  O O   . LYS A 1 362 ? 9.372   -28.473 -53.456 1.00 64.52  ? 362 LYS A O   1 
ATOM   2910  C CB  . LYS A 1 362 ? 7.343   -25.975 -54.451 1.00 75.17  ? 362 LYS A CB  1 
ATOM   2911  C CG  . LYS A 1 362 ? 5.834   -25.809 -54.398 1.00 82.08  ? 362 LYS A CG  1 
ATOM   2912  C CD  . LYS A 1 362 ? 5.254   -25.226 -55.663 1.00 86.96  ? 362 LYS A CD  1 
ATOM   2913  C CE  . LYS A 1 362 ? 3.866   -24.660 -55.451 1.00 92.00  ? 362 LYS A CE  1 
ATOM   2914  N NZ  . LYS A 1 362 ? 3.305   -24.104 -56.704 1.00 87.89  ? 362 LYS A NZ  1 
ATOM   2915  N N   . LYS A 1 363 ? 10.265  -26.469 -54.010 1.00 69.25  ? 363 LYS A N   1 
ATOM   2916  C CA  . LYS A 1 363 ? 11.532  -27.023 -54.449 1.00 66.83  ? 363 LYS A CA  1 
ATOM   2917  C C   . LYS A 1 363 ? 12.232  -27.712 -53.280 1.00 72.09  ? 363 LYS A C   1 
ATOM   2918  O O   . LYS A 1 363 ? 12.704  -28.832 -53.437 1.00 71.10  ? 363 LYS A O   1 
ATOM   2919  C CB  . LYS A 1 363 ? 12.356  -25.926 -55.116 1.00 68.77  ? 363 LYS A CB  1 
ATOM   2920  C CG  . LYS A 1 363 ? 11.731  -25.457 -56.420 1.00 72.88  ? 363 LYS A CG  1 
ATOM   2921  C CD  . LYS A 1 363 ? 12.227  -24.131 -56.922 1.00 76.78  ? 363 LYS A CD  1 
ATOM   2922  C CE  . LYS A 1 363 ? 11.318  -23.565 -57.990 1.00 78.51  ? 363 LYS A CE  1 
ATOM   2923  N NZ  . LYS A 1 363 ? 11.616  -22.139 -58.245 1.00 82.01  ? 363 LYS A NZ  1 
ATOM   2924  N N   . HIS A 1 364 ? 12.252  -27.087 -52.097 1.00 71.46  ? 364 HIS A N   1 
ATOM   2925  C CA  . HIS A 1 364 ? 12.833  -27.719 -50.917 1.00 67.08  ? 364 HIS A CA  1 
ATOM   2926  C C   . HIS A 1 364 ? 12.190  -29.092 -50.658 1.00 73.65  ? 364 HIS A C   1 
ATOM   2927  O O   . HIS A 1 364 ? 12.856  -30.003 -50.164 1.00 71.95  ? 364 HIS A O   1 
ATOM   2928  C CB  . HIS A 1 364 ? 12.749  -26.762 -49.725 1.00 65.69  ? 364 HIS A CB  1 
ATOM   2929  C CG  . HIS A 1 364 ? 13.204  -27.324 -48.413 1.00 70.41  ? 364 HIS A CG  1 
ATOM   2930  N ND1 . HIS A 1 364 ? 12.346  -27.531 -47.348 1.00 73.40  ? 364 HIS A ND1 1 
ATOM   2931  C CD2 . HIS A 1 364 ? 14.424  -27.688 -47.980 1.00 69.66  ? 364 HIS A CD2 1 
ATOM   2932  C CE1 . HIS A 1 364 ? 13.033  -27.987 -46.307 1.00 75.15  ? 364 HIS A CE1 1 
ATOM   2933  N NE2 . HIS A 1 364 ? 14.298  -28.103 -46.674 1.00 72.93  ? 364 HIS A NE2 1 
ATOM   2934  N N   . GLY A 1 365 ? 10.881  -29.222 -50.931 1.00 73.48  ? 365 GLY A N   1 
ATOM   2935  C CA  . GLY A 1 365 ? 10.230  -30.512 -51.121 1.00 72.30  ? 365 GLY A CA  1 
ATOM   2936  C C   . GLY A 1 365 ? 9.869   -31.297 -49.852 1.00 69.92  ? 365 GLY A C   1 
ATOM   2937  O O   . GLY A 1 365 ? 9.411   -32.431 -49.980 1.00 64.58  ? 365 GLY A O   1 
ATOM   2938  N N   . LYS A 1 366 ? 10.047  -30.715 -48.651 1.00 79.13  ? 366 LYS A N   1 
ATOM   2939  C CA  . LYS A 1 366 ? 9.752   -31.394 -47.386 1.00 81.67  ? 366 LYS A CA  1 
ATOM   2940  C C   . LYS A 1 366 ? 8.334   -31.075 -46.891 1.00 72.08  ? 366 LYS A C   1 
ATOM   2941  O O   . LYS A 1 366 ? 7.668   -31.955 -46.355 1.00 55.51  ? 366 LYS A O   1 
ATOM   2942  C CB  . LYS A 1 366 ? 10.702  -30.992 -46.245 1.00 82.87  ? 366 LYS A CB  1 
ATOM   2943  C CG  . LYS A 1 366 ? 12.192  -30.978 -46.554 1.00 90.79  ? 366 LYS A CG  1 
ATOM   2944  C CD  . LYS A 1 366 ? 12.990  -32.198 -46.146 1.00 99.52  ? 366 LYS A CD  1 
ATOM   2945  C CE  . LYS A 1 366 ? 14.476  -31.886 -46.141 1.00 106.58 ? 366 LYS A CE  1 
ATOM   2946  N NZ  . LYS A 1 366 ? 15.317  -33.066 -45.827 1.00 107.90 ? 366 LYS A NZ  1 
ATOM   2947  N N   . ALA A 1 367 ? 7.899   -29.807 -47.003 1.00 66.76  ? 367 ALA A N   1 
ATOM   2948  C CA  . ALA A 1 367 ? 6.557   -29.414 -46.591 1.00 70.87  ? 367 ALA A CA  1 
ATOM   2949  C C   . ALA A 1 367 ? 5.527   -30.089 -47.496 1.00 64.67  ? 367 ALA A C   1 
ATOM   2950  O O   . ALA A 1 367 ? 5.641   -30.017 -48.719 1.00 62.17  ? 367 ALA A O   1 
ATOM   2951  C CB  . ALA A 1 367 ? 6.407   -27.905 -46.617 1.00 74.27  ? 367 ALA A CB  1 
ATOM   2952  N N   . LYS A 1 368 ? 4.531   -30.760 -46.893 1.00 61.05  ? 368 LYS A N   1 
ATOM   2953  C CA  . LYS A 1 368 ? 3.433   -31.319 -47.668 1.00 64.47  ? 368 LYS A CA  1 
ATOM   2954  C C   . LYS A 1 368 ? 2.606   -30.170 -48.269 1.00 65.17  ? 368 LYS A C   1 
ATOM   2955  O O   . LYS A 1 368 ? 2.058   -30.322 -49.359 1.00 59.62  ? 368 LYS A O   1 
ATOM   2956  C CB  . LYS A 1 368 ? 2.611   -32.288 -46.808 1.00 63.54  ? 368 LYS A CB  1 
ATOM   2957  N N   . ASN A 1 369 ? 2.571   -29.007 -47.581 1.00 57.92  ? 369 ASN A N   1 
ATOM   2958  C CA  . ASN A 1 369 ? 1.766   -27.847 -47.964 1.00 62.91  ? 369 ASN A CA  1 
ATOM   2959  C C   . ASN A 1 369 ? 2.645   -26.589 -48.029 1.00 65.22  ? 369 ASN A C   1 
ATOM   2960  O O   . ASN A 1 369 ? 3.051   -26.051 -46.984 1.00 60.67  ? 369 ASN A O   1 
ATOM   2961  C CB  . ASN A 1 369 ? 0.604   -27.627 -46.983 1.00 65.49  ? 369 ASN A CB  1 
ATOM   2962  C CG  . ASN A 1 369 ? -0.134  -26.315 -47.188 1.00 65.58  ? 369 ASN A CG  1 
ATOM   2963  O OD1 . ASN A 1 369 ? -0.240  -25.811 -48.306 1.00 58.51  ? 369 ASN A OD1 1 
ATOM   2964  N ND2 . ASN A 1 369 ? -0.676  -25.771 -46.111 1.00 73.98  ? 369 ASN A ND2 1 
ATOM   2965  N N   . PRO A 1 370 ? 2.921   -26.049 -49.247 1.00 64.24  ? 370 PRO A N   1 
ATOM   2966  C CA  . PRO A 1 370 ? 3.835   -24.914 -49.417 1.00 67.44  ? 370 PRO A CA  1 
ATOM   2967  C C   . PRO A 1 370 ? 3.221   -23.518 -49.273 1.00 69.05  ? 370 PRO A C   1 
ATOM   2968  O O   . PRO A 1 370 ? 3.900   -22.523 -49.521 1.00 65.56  ? 370 PRO A O   1 
ATOM   2969  C CB  . PRO A 1 370 ? 4.245   -25.095 -50.883 1.00 70.70  ? 370 PRO A CB  1 
ATOM   2970  C CG  . PRO A 1 370 ? 2.952   -25.523 -51.540 1.00 67.15  ? 370 PRO A CG  1 
ATOM   2971  C CD  . PRO A 1 370 ? 2.342   -26.483 -50.535 1.00 65.62  ? 370 PRO A CD  1 
ATOM   2972  N N   . TRP A 1 371 ? 1.943   -23.458 -48.866 1.00 69.29  ? 371 TRP A N   1 
ATOM   2973  C CA  . TRP A 1 371 ? 1.147   -22.239 -48.927 1.00 65.89  ? 371 TRP A CA  1 
ATOM   2974  C C   . TRP A 1 371 ? 0.906   -21.704 -47.520 1.00 60.30  ? 371 TRP A C   1 
ATOM   2975  O O   . TRP A 1 371 ? 1.093   -22.440 -46.538 1.00 52.33  ? 371 TRP A O   1 
ATOM   2976  C CB  . TRP A 1 371 ? -0.172  -22.506 -49.654 1.00 68.21  ? 371 TRP A CB  1 
ATOM   2977  C CG  . TRP A 1 371 ? 0.007   -22.909 -51.082 1.00 70.83  ? 371 TRP A CG  1 
ATOM   2978  C CD1 . TRP A 1 371 ? -0.040  -24.176 -51.592 1.00 76.01  ? 371 TRP A CD1 1 
ATOM   2979  C CD2 . TRP A 1 371 ? 0.241   -22.034 -52.196 1.00 74.71  ? 371 TRP A CD2 1 
ATOM   2980  N NE1 . TRP A 1 371 ? 0.157   -24.153 -52.949 1.00 68.76  ? 371 TRP A NE1 1 
ATOM   2981  C CE2 . TRP A 1 371 ? 0.334   -22.852 -53.346 1.00 77.78  ? 371 TRP A CE2 1 
ATOM   2982  C CE3 . TRP A 1 371 ? 0.369   -20.646 -52.337 1.00 77.10  ? 371 TRP A CE3 1 
ATOM   2983  C CZ2 . TRP A 1 371 ? 0.554   -22.319 -54.614 1.00 68.79  ? 371 TRP A CZ2 1 
ATOM   2984  C CZ3 . TRP A 1 371 ? 0.577   -20.120 -53.593 1.00 73.12  ? 371 TRP A CZ3 1 
ATOM   2985  C CH2 . TRP A 1 371 ? 0.672   -20.950 -54.712 1.00 76.61  ? 371 TRP A CH2 1 
ATOM   2986  N N   . PRO A 1 372 ? 0.498   -20.412 -47.400 1.00 51.70  ? 372 PRO A N   1 
ATOM   2987  C CA  . PRO A 1 372 ? 0.248   -19.790 -46.098 1.00 50.66  ? 372 PRO A CA  1 
ATOM   2988  C C   . PRO A 1 372 ? -1.056  -20.252 -45.442 1.00 47.19  ? 372 PRO A C   1 
ATOM   2989  O O   . PRO A 1 372 ? -2.042  -20.567 -46.118 1.00 46.01  ? 372 PRO A O   1 
ATOM   2990  C CB  . PRO A 1 372 ? 0.223   -18.275 -46.387 1.00 46.60  ? 372 PRO A CB  1 
ATOM   2991  C CG  . PRO A 1 372 ? 0.029   -18.126 -47.868 1.00 46.72  ? 372 PRO A CG  1 
ATOM   2992  C CD  . PRO A 1 372 ? 0.276   -19.475 -48.503 1.00 45.60  ? 372 PRO A CD  1 
ATOM   2993  N N   . ASN A 1 373 ? -1.018  -20.329 -44.110 1.00 45.13  ? 373 ASN A N   1 
ATOM   2994  C CA  . ASN A 1 373 ? -2.210  -20.563 -43.306 1.00 47.93  ? 373 ASN A CA  1 
ATOM   2995  C C   . ASN A 1 373 ? -2.710  -19.239 -42.686 1.00 49.64  ? 373 ASN A C   1 
ATOM   2996  O O   . ASN A 1 373 ? -2.124  -18.165 -42.846 1.00 44.21  ? 373 ASN A O   1 
ATOM   2997  C CB  . ASN A 1 373 ? -1.925  -21.656 -42.269 1.00 47.39  ? 373 ASN A CB  1 
ATOM   2998  C CG  . ASN A 1 373 ? -0.740  -21.358 -41.383 1.00 48.60  ? 373 ASN A CG  1 
ATOM   2999  O OD1 . ASN A 1 373 ? -0.702  -20.318 -40.730 1.00 48.12  ? 373 ASN A OD1 1 
ATOM   3000  N ND2 . ASN A 1 373 ? 0.252   -22.240 -41.368 1.00 54.68  ? 373 ASN A ND2 1 
ATOM   3001  N N   . VAL A 1 374 ? -3.795  -19.315 -41.912 1.00 49.60  ? 374 VAL A N   1 
ATOM   3002  C CA  . VAL A 1 374 ? -4.412  -18.133 -41.317 1.00 43.56  ? 374 VAL A CA  1 
ATOM   3003  C C   . VAL A 1 374 ? -3.393  -17.317 -40.517 1.00 40.01  ? 374 VAL A C   1 
ATOM   3004  O O   . VAL A 1 374 ? -3.428  -16.084 -40.588 1.00 36.57  ? 374 VAL A O   1 
ATOM   3005  C CB  . VAL A 1 374 ? -5.631  -18.545 -40.467 1.00 45.19  ? 374 VAL A CB  1 
ATOM   3006  C CG1 . VAL A 1 374 ? -5.249  -19.464 -39.309 1.00 46.20  ? 374 VAL A CG1 1 
ATOM   3007  C CG2 . VAL A 1 374 ? -6.406  -17.334 -39.965 1.00 47.03  ? 374 VAL A CG2 1 
ATOM   3008  N N   . ASP A 1 375 ? -2.419  -17.995 -39.867 1.00 36.30  ? 375 ASP A N   1 
ATOM   3009  C CA  . ASP A 1 375 ? -1.513  -17.351 -38.926 1.00 38.90  ? 375 ASP A CA  1 
ATOM   3010  C C   . ASP A 1 375 ? -0.433  -16.516 -39.611 1.00 39.02  ? 375 ASP A C   1 
ATOM   3011  O O   . ASP A 1 375 ? 0.267   -15.730 -38.963 1.00 37.35  ? 375 ASP A O   1 
ATOM   3012  C CB  . ASP A 1 375 ? -0.918  -18.383 -37.977 1.00 42.86  ? 375 ASP A CB  1 
ATOM   3013  C CG  . ASP A 1 375 ? -2.012  -19.165 -37.259 1.00 60.36  ? 375 ASP A CG  1 
ATOM   3014  O OD1 . ASP A 1 375 ? -2.895  -18.497 -36.621 1.00 54.62  ? 375 ASP A OD1 1 
ATOM   3015  O OD2 . ASP A 1 375 ? -1.997  -20.435 -37.353 1.00 60.46  ? 375 ASP A OD2 1 
ATOM   3016  N N   . ALA A 1 376 ? -0.276  -16.667 -40.922 1.00 37.05  ? 376 ALA A N   1 
ATOM   3017  C CA  . ALA A 1 376 ? 0.715   -15.875 -41.622 1.00 35.62  ? 376 ALA A CA  1 
ATOM   3018  C C   . ALA A 1 376 ? 0.274   -14.406 -41.694 1.00 39.52  ? 376 ALA A C   1 
ATOM   3019  O O   . ALA A 1 376 ? 1.099   -13.538 -41.957 1.00 35.53  ? 376 ALA A O   1 
ATOM   3020  C CB  . ALA A 1 376 ? 0.971   -16.437 -42.994 1.00 34.67  ? 376 ALA A CB  1 
ATOM   3021  N N   . HIS A 1 377 ? -1.016  -14.102 -41.463 1.00 39.93  ? 377 HIS A N   1 
ATOM   3022  C CA  . HIS A 1 377 ? -1.509  -12.768 -41.777 1.00 37.37  ? 377 HIS A CA  1 
ATOM   3023  C C   . HIS A 1 377 ? -2.104  -12.018 -40.577 1.00 35.72  ? 377 HIS A C   1 
ATOM   3024  O O   . HIS A 1 377 ? -2.241  -10.797 -40.644 1.00 32.68  ? 377 HIS A O   1 
ATOM   3025  C CB  . HIS A 1 377 ? -2.537  -12.832 -42.899 1.00 34.54  ? 377 HIS A CB  1 
ATOM   3026  C CG  . HIS A 1 377 ? -2.452  -11.666 -43.822 1.00 38.14  ? 377 HIS A CG  1 
ATOM   3027  N ND1 . HIS A 1 377 ? -2.367  -10.365 -43.380 1.00 43.33  ? 377 HIS A ND1 1 
ATOM   3028  C CD2 . HIS A 1 377 ? -2.403  -11.611 -45.164 1.00 40.92  ? 377 HIS A CD2 1 
ATOM   3029  C CE1 . HIS A 1 377 ? -2.293  -9.558  -44.433 1.00 47.52  ? 377 HIS A CE1 1 
ATOM   3030  N NE2 . HIS A 1 377 ? -2.292  -10.292 -45.525 1.00 38.85  ? 377 HIS A NE2 1 
ATOM   3031  N N   . SER A 1 378 ? -2.485  -12.710 -39.499 1.00 36.01  ? 378 SER A N   1 
ATOM   3032  C CA  . SER A 1 378 ? -3.255  -12.062 -38.437 1.00 38.52  ? 378 SER A CA  1 
ATOM   3033  C C   . SER A 1 378 ? -2.420  -11.053 -37.634 1.00 35.49  ? 378 SER A C   1 
ATOM   3034  O O   . SER A 1 378 ? -2.890  -9.981  -37.275 1.00 35.26  ? 378 SER A O   1 
ATOM   3035  C CB  . SER A 1 378 ? -3.878  -13.102 -37.545 1.00 38.61  ? 378 SER A CB  1 
ATOM   3036  O OG  . SER A 1 378 ? -2.896  -14.047 -37.147 1.00 42.12  ? 378 SER A OG  1 
ATOM   3037  N N   . GLY A 1 379 ? -1.172  -11.377 -37.311 1.00 37.91  ? 379 GLY A N   1 
ATOM   3038  C CA  . GLY A 1 379 ? -0.379  -10.531 -36.420 1.00 37.14  ? 379 GLY A CA  1 
ATOM   3039  C C   . GLY A 1 379 ? -0.130  -9.125  -36.962 1.00 37.14  ? 379 GLY A C   1 
ATOM   3040  O O   . GLY A 1 379 ? -0.147  -8.134  -36.213 1.00 31.38  ? 379 GLY A O   1 
ATOM   3041  N N   . VAL A 1 380 ? 0.125   -9.005  -38.268 1.00 34.06  ? 380 VAL A N   1 
ATOM   3042  C CA  . VAL A 1 380 ? 0.441   -7.680  -38.772 1.00 37.27  ? 380 VAL A CA  1 
ATOM   3043  C C   . VAL A 1 380 ? -0.799  -6.806  -38.709 1.00 31.69  ? 380 VAL A C   1 
ATOM   3044  O O   . VAL A 1 380 ? -0.671  -5.594  -38.590 1.00 33.96  ? 380 VAL A O   1 
ATOM   3045  C CB  . VAL A 1 380 ? 1.016   -7.633  -40.196 1.00 37.29  ? 380 VAL A CB  1 
ATOM   3046  C CG1 . VAL A 1 380 ? 2.367   -8.296  -40.254 1.00 44.35  ? 380 VAL A CG1 1 
ATOM   3047  C CG2 . VAL A 1 380 ? 0.057   -8.205  -41.214 1.00 40.63  ? 380 VAL A CG2 1 
ATOM   3048  N N   . LEU A 1 381 ? -1.984  -7.393  -38.801 1.00 31.09  ? 381 LEU A N   1 
ATOM   3049  C CA  . LEU A 1 381 ? -3.211  -6.596  -38.719 1.00 29.67  ? 381 LEU A CA  1 
ATOM   3050  C C   . LEU A 1 381 ? -3.399  -6.063  -37.302 1.00 32.24  ? 381 LEU A C   1 
ATOM   3051  O O   . LEU A 1 381 ? -3.627  -4.871  -37.091 1.00 35.65  ? 381 LEU A O   1 
ATOM   3052  C CB  . LEU A 1 381 ? -4.386  -7.480  -39.123 1.00 36.67  ? 381 LEU A CB  1 
ATOM   3053  C CG  . LEU A 1 381 ? -4.369  -8.013  -40.555 1.00 40.23  ? 381 LEU A CG  1 
ATOM   3054  C CD1 . LEU A 1 381 ? -5.612  -8.836  -40.823 1.00 41.88  ? 381 LEU A CD1 1 
ATOM   3055  C CD2 . LEU A 1 381 ? -4.285  -6.879  -41.557 1.00 41.41  ? 381 LEU A CD2 1 
ATOM   3056  N N   . LEU A 1 382 ? -3.287  -6.943  -36.301 1.00 33.25  ? 382 LEU A N   1 
ATOM   3057  C CA  . LEU A 1 382 ? -3.409  -6.525  -34.901 1.00 33.38  ? 382 LEU A CA  1 
ATOM   3058  C C   . LEU A 1 382 ? -2.351  -5.465  -34.569 1.00 29.98  ? 382 LEU A C   1 
ATOM   3059  O O   . LEU A 1 382 ? -2.610  -4.452  -33.926 1.00 30.08  ? 382 LEU A O   1 
ATOM   3060  C CB  . LEU A 1 382 ? -3.225  -7.742  -33.993 1.00 30.30  ? 382 LEU A CB  1 
ATOM   3061  C CG  . LEU A 1 382 ? -4.313  -8.802  -34.102 1.00 32.83  ? 382 LEU A CG  1 
ATOM   3062  C CD1 . LEU A 1 382 ? -3.937  -10.065 -33.349 1.00 31.83  ? 382 LEU A CD1 1 
ATOM   3063  C CD2 . LEU A 1 382 ? -5.646  -8.251  -33.629 1.00 33.83  ? 382 LEU A CD2 1 
ATOM   3064  N N   . TRP A 1 383 ? -1.112  -5.765  -34.946 1.00 32.59  ? 383 TRP A N   1 
ATOM   3065  C CA  . TRP A 1 383 ? 0.003   -4.897  -34.643 1.00 31.54  ? 383 TRP A CA  1 
ATOM   3066  C C   . TRP A 1 383 ? -0.239  -3.508  -35.239 1.00 32.03  ? 383 TRP A C   1 
ATOM   3067  O O   . TRP A 1 383 ? -0.079  -2.523  -34.558 1.00 31.43  ? 383 TRP A O   1 
ATOM   3068  C CB  . TRP A 1 383 ? 1.320   -5.517  -35.110 1.00 30.76  ? 383 TRP A CB  1 
ATOM   3069  C CG  . TRP A 1 383 ? 2.509   -4.698  -34.730 1.00 30.65  ? 383 TRP A CG  1 
ATOM   3070  C CD1 . TRP A 1 383 ? 3.011   -3.622  -35.405 1.00 31.17  ? 383 TRP A CD1 1 
ATOM   3071  C CD2 . TRP A 1 383 ? 3.302   -4.840  -33.543 1.00 29.31  ? 383 TRP A CD2 1 
ATOM   3072  N NE1 . TRP A 1 383 ? 4.052   -3.080  -34.710 1.00 30.82  ? 383 TRP A NE1 1 
ATOM   3073  C CE2 . TRP A 1 383 ? 4.278   -3.827  -33.583 1.00 29.56  ? 383 TRP A CE2 1 
ATOM   3074  C CE3 . TRP A 1 383 ? 3.306   -5.734  -32.470 1.00 32.34  ? 383 TRP A CE3 1 
ATOM   3075  C CZ2 . TRP A 1 383 ? 5.264   -3.706  -32.603 1.00 37.09  ? 383 TRP A CZ2 1 
ATOM   3076  C CZ3 . TRP A 1 383 ? 4.278   -5.613  -31.499 1.00 36.02  ? 383 TRP A CZ3 1 
ATOM   3077  C CH2 . TRP A 1 383 ? 5.231   -4.589  -31.549 1.00 35.61  ? 383 TRP A CH2 1 
ATOM   3078  N N   . HIS A 1 384 ? -0.737  -3.435  -36.465 1.00 31.66  ? 384 HIS A N   1 
ATOM   3079  C CA  . HIS A 1 384 ? -0.928  -2.147  -37.127 1.00 38.24  ? 384 HIS A CA  1 
ATOM   3080  C C   . HIS A 1 384 ? -1.887  -1.241  -36.338 1.00 38.03  ? 384 HIS A C   1 
ATOM   3081  O O   . HIS A 1 384 ? -1.747  -0.024  -36.329 1.00 37.75  ? 384 HIS A O   1 
ATOM   3082  C CB  . HIS A 1 384 ? -1.470  -2.393  -38.539 1.00 35.11  ? 384 HIS A CB  1 
ATOM   3083  C CG  . HIS A 1 384 ? -1.838  -1.140  -39.223 1.00 42.37  ? 384 HIS A CG  1 
ATOM   3084  N ND1 . HIS A 1 384 ? -0.912  -0.344  -39.871 1.00 44.09  ? 384 HIS A ND1 1 
ATOM   3085  C CD2 . HIS A 1 384 ? -3.032  -0.535  -39.344 1.00 38.16  ? 384 HIS A CD2 1 
ATOM   3086  C CE1 . HIS A 1 384 ? -1.540  0.705   -40.363 1.00 45.91  ? 384 HIS A CE1 1 
ATOM   3087  N NE2 . HIS A 1 384 ? -2.819  0.602   -40.054 1.00 42.45  ? 384 HIS A NE2 1 
ATOM   3088  N N   . TYR A 1 385 ? -2.896  -1.829  -35.695 1.00 33.06  ? 385 TYR A N   1 
ATOM   3089  C CA  . TYR A 1 385 ? -3.954  -1.088  -35.037 1.00 33.09  ? 385 TYR A CA  1 
ATOM   3090  C C   . TYR A 1 385 ? -3.653  -0.886  -33.553 1.00 35.70  ? 385 TYR A C   1 
ATOM   3091  O O   . TYR A 1 385 ? -4.463  -0.304  -32.841 1.00 34.48  ? 385 TYR A O   1 
ATOM   3092  C CB  . TYR A 1 385 ? -5.301  -1.782  -35.265 1.00 34.10  ? 385 TYR A CB  1 
ATOM   3093  C CG  . TYR A 1 385 ? -5.835  -1.592  -36.659 1.00 34.80  ? 385 TYR A CG  1 
ATOM   3094  C CD1 . TYR A 1 385 ? -6.311  -0.361  -37.092 1.00 38.30  ? 385 TYR A CD1 1 
ATOM   3095  C CD2 . TYR A 1 385 ? -5.791  -2.628  -37.578 1.00 38.81  ? 385 TYR A CD2 1 
ATOM   3096  C CE1 . TYR A 1 385 ? -6.812  -0.190  -38.379 1.00 36.86  ? 385 TYR A CE1 1 
ATOM   3097  C CE2 . TYR A 1 385 ? -6.245  -2.465  -38.875 1.00 36.85  ? 385 TYR A CE2 1 
ATOM   3098  C CZ  . TYR A 1 385 ? -6.747  -1.245  -39.278 1.00 36.10  ? 385 TYR A CZ  1 
ATOM   3099  O OH  . TYR A 1 385 ? -7.159  -1.173  -40.570 1.00 40.23  ? 385 TYR A OH  1 
ATOM   3100  N N   . GLY A 1 386 ? -2.468  -1.314  -33.103 1.00 35.46  ? 386 GLY A N   1 
ATOM   3101  C CA  . GLY A 1 386 ? -1.994  -0.990  -31.766 1.00 36.33  ? 386 GLY A CA  1 
ATOM   3102  C C   . GLY A 1 386 ? -2.220  -2.115  -30.746 1.00 35.60  ? 386 GLY A C   1 
ATOM   3103  O O   . GLY A 1 386 ? -2.085  -1.891  -29.542 1.00 36.44  ? 386 GLY A O   1 
ATOM   3104  N N   . ILE A 1 387 ? -2.598  -3.318  -31.208 1.00 32.40  ? 387 ILE A N   1 
ATOM   3105  C CA  . ILE A 1 387 ? -2.660  -4.469  -30.329 1.00 31.50  ? 387 ILE A CA  1 
ATOM   3106  C C   . ILE A 1 387 ? -1.312  -5.176  -30.448 1.00 28.91  ? 387 ILE A C   1 
ATOM   3107  O O   . ILE A 1 387 ? -1.081  -5.931  -31.404 1.00 28.75  ? 387 ILE A O   1 
ATOM   3108  C CB  . ILE A 1 387 ? -3.861  -5.409  -30.616 1.00 32.82  ? 387 ILE A CB  1 
ATOM   3109  C CG1 . ILE A 1 387 ? -5.225  -4.731  -30.545 1.00 39.98  ? 387 ILE A CG1 1 
ATOM   3110  C CG2 . ILE A 1 387 ? -3.857  -6.554  -29.630 1.00 34.76  ? 387 ILE A CG2 1 
ATOM   3111  C CD1 . ILE A 1 387 ? -5.774  -4.261  -31.849 1.00 44.52  ? 387 ILE A CD1 1 
ATOM   3112  N N   . ARG A 1 388 ? -0.414  -4.887  -29.501 1.00 27.35  ? 388 ARG A N   1 
ATOM   3113  C CA  . ARG A 1 388 ? 0.975   -5.278  -29.587 1.00 31.39  ? 388 ARG A CA  1 
ATOM   3114  C C   . ARG A 1 388 ? 1.392   -6.304  -28.542 1.00 32.68  ? 388 ARG A C   1 
ATOM   3115  O O   . ARG A 1 388 ? 2.562   -6.664  -28.473 1.00 31.50  ? 388 ARG A O   1 
ATOM   3116  C CB  . ARG A 1 388 ? 1.840   -4.029  -29.433 1.00 35.81  ? 388 ARG A CB  1 
ATOM   3117  C CG  . ARG A 1 388 ? 1.498   -3.036  -30.524 1.00 36.78  ? 388 ARG A CG  1 
ATOM   3118  C CD  . ARG A 1 388 ? 2.513   -1.992  -30.877 1.00 42.22  ? 388 ARG A CD  1 
ATOM   3119  N NE  . ARG A 1 388 ? 2.048   -1.593  -32.216 1.00 51.35  ? 388 ARG A NE  1 
ATOM   3120  C CZ  . ARG A 1 388 ? 2.584   -0.634  -32.950 1.00 50.93  ? 388 ARG A CZ  1 
ATOM   3121  N NH1 . ARG A 1 388 ? 3.699   -0.048  -32.547 1.00 47.32  ? 388 ARG A NH1 1 
ATOM   3122  N NH2 . ARG A 1 388 ? 2.007   -0.288  -34.085 1.00 50.97  ? 388 ARG A NH2 1 
ATOM   3123  N N   . GLU A 1 389 ? 0.451   -6.787  -27.745 1.00 30.85  ? 389 GLU A N   1 
ATOM   3124  C CA  . GLU A 1 389 ? 0.807   -7.643  -26.632 1.00 30.69  ? 389 GLU A CA  1 
ATOM   3125  C C   . GLU A 1 389 ? 0.740   -9.085  -27.100 1.00 31.31  ? 389 GLU A C   1 
ATOM   3126  O O   . GLU A 1 389 ? -0.313  -9.716  -27.041 1.00 31.12  ? 389 GLU A O   1 
ATOM   3127  C CB  . GLU A 1 389 ? -0.150  -7.363  -25.480 1.00 34.32  ? 389 GLU A CB  1 
ATOM   3128  C CG  . GLU A 1 389 ? -0.032  -5.952  -24.959 1.00 34.69  ? 389 GLU A CG  1 
ATOM   3129  C CD  . GLU A 1 389 ? -0.696  -4.834  -25.751 1.00 37.59  ? 389 GLU A CD  1 
ATOM   3130  O OE1 . GLU A 1 389 ? -0.413  -3.680  -25.432 1.00 40.72  ? 389 GLU A OE1 1 
ATOM   3131  O OE2 . GLU A 1 389 ? -1.532  -5.102  -26.637 1.00 33.02  ? 389 GLU A OE2 1 
ATOM   3132  N N   . TYR A 1 390 ? 1.878   -9.580  -27.586 1.00 32.40  ? 390 TYR A N   1 
ATOM   3133  C CA  . TYR A 1 390 ? 1.960   -10.852 -28.297 1.00 33.47  ? 390 TYR A CA  1 
ATOM   3134  C C   . TYR A 1 390 ? 1.227   -11.973 -27.569 1.00 31.86  ? 390 TYR A C   1 
ATOM   3135  O O   . TYR A 1 390 ? 0.473   -12.735 -28.183 1.00 28.42  ? 390 TYR A O   1 
ATOM   3136  C CB  . TYR A 1 390 ? 3.422   -11.289 -28.447 1.00 33.22  ? 390 TYR A CB  1 
ATOM   3137  C CG  . TYR A 1 390 ? 4.311   -10.387 -29.269 1.00 35.77  ? 390 TYR A CG  1 
ATOM   3138  C CD1 . TYR A 1 390 ? 4.372   -10.496 -30.656 1.00 37.05  ? 390 TYR A CD1 1 
ATOM   3139  C CD2 . TYR A 1 390 ? 5.127   -9.458  -28.652 1.00 33.93  ? 390 TYR A CD2 1 
ATOM   3140  C CE1 . TYR A 1 390 ? 5.219   -9.696  -31.399 1.00 33.54  ? 390 TYR A CE1 1 
ATOM   3141  C CE2 . TYR A 1 390 ? 5.992   -8.661  -29.374 1.00 35.12  ? 390 TYR A CE2 1 
ATOM   3142  C CZ  . TYR A 1 390 ? 6.040   -8.790  -30.754 1.00 38.75  ? 390 TYR A CZ  1 
ATOM   3143  O OH  . TYR A 1 390 ? 6.903   -7.991  -31.449 1.00 37.93  ? 390 TYR A OH  1 
ATOM   3144  N N   . ASP A 1 391 ? 1.468   -12.108 -26.260 1.00 28.90  ? 391 ASP A N   1 
ATOM   3145  C CA  . ASP A 1 391 ? 0.922   -13.237 -25.499 1.00 31.41  ? 391 ASP A CA  1 
ATOM   3146  C C   . ASP A 1 391 ? -0.612  -13.237 -25.510 1.00 30.13  ? 391 ASP A C   1 
ATOM   3147  O O   . ASP A 1 391 ? -1.256  -14.290 -25.456 1.00 29.51  ? 391 ASP A O   1 
ATOM   3148  C CB  . ASP A 1 391 ? 1.415   -13.235 -24.051 1.00 33.70  ? 391 ASP A CB  1 
ATOM   3149  C CG  . ASP A 1 391 ? 2.895   -13.584 -23.872 1.00 37.14  ? 391 ASP A CG  1 
ATOM   3150  O OD1 . ASP A 1 391 ? 3.540   -14.089 -24.836 1.00 40.30  ? 391 ASP A OD1 1 
ATOM   3151  O OD2 . ASP A 1 391 ? 3.404   -13.305 -22.798 1.00 42.02  ? 391 ASP A OD2 1 
ATOM   3152  N N   . PHE A 1 392 ? -1.193  -12.046 -25.652 1.00 26.74  ? 392 PHE A N   1 
ATOM   3153  C CA  . PHE A 1 392 ? -2.630  -11.904 -25.587 1.00 25.72  ? 392 PHE A CA  1 
ATOM   3154  C C   . PHE A 1 392 ? -3.298  -12.346 -26.892 1.00 24.97  ? 392 PHE A C   1 
ATOM   3155  O O   . PHE A 1 392 ? -4.501  -12.570 -26.920 1.00 25.56  ? 392 PHE A O   1 
ATOM   3156  C CB  . PHE A 1 392 ? -2.960  -10.443 -25.274 1.00 27.66  ? 392 PHE A CB  1 
ATOM   3157  C CG  . PHE A 1 392 ? -4.404  -10.252 -24.912 1.00 28.73  ? 392 PHE A CG  1 
ATOM   3158  C CD1 . PHE A 1 392 ? -4.877  -10.607 -23.660 1.00 23.96  ? 392 PHE A CD1 1 
ATOM   3159  C CD2 . PHE A 1 392 ? -5.290  -9.755  -25.846 1.00 25.07  ? 392 PHE A CD2 1 
ATOM   3160  C CE1 . PHE A 1 392 ? -6.224  -10.443 -23.336 1.00 25.40  ? 392 PHE A CE1 1 
ATOM   3161  C CE2 . PHE A 1 392 ? -6.628  -9.602  -25.519 1.00 25.35  ? 392 PHE A CE2 1 
ATOM   3162  C CZ  . PHE A 1 392 ? -7.089  -9.924  -24.270 1.00 24.29  ? 392 PHE A CZ  1 
ATOM   3163  N N   . TYR A 1 393 ? -2.528  -12.467 -27.979 1.00 25.65  ? 393 TYR A N   1 
ATOM   3164  C CA  . TYR A 1 393 ? -3.084  -12.870 -29.265 1.00 26.45  ? 393 TYR A CA  1 
ATOM   3165  C C   . TYR A 1 393 ? -3.820  -14.201 -29.152 1.00 27.94  ? 393 TYR A C   1 
ATOM   3166  O O   . TYR A 1 393 ? -4.823  -14.409 -29.842 1.00 28.09  ? 393 TYR A O   1 
ATOM   3167  C CB  . TYR A 1 393 ? -2.001  -12.956 -30.338 1.00 27.55  ? 393 TYR A CB  1 
ATOM   3168  C CG  . TYR A 1 393 ? -1.434  -11.631 -30.783 1.00 28.15  ? 393 TYR A CG  1 
ATOM   3169  C CD1 . TYR A 1 393 ? -1.778  -10.417 -30.200 1.00 27.64  ? 393 TYR A CD1 1 
ATOM   3170  C CD2 . TYR A 1 393 ? -0.523  -11.603 -31.820 1.00 32.14  ? 393 TYR A CD2 1 
ATOM   3171  C CE1 . TYR A 1 393 ? -1.218  -9.219  -30.634 1.00 28.71  ? 393 TYR A CE1 1 
ATOM   3172  C CE2 . TYR A 1 393 ? 0.054   -10.424 -32.255 1.00 32.41  ? 393 TYR A CE2 1 
ATOM   3173  C CZ  . TYR A 1 393 ? -0.306  -9.222  -31.678 1.00 33.52  ? 393 TYR A CZ  1 
ATOM   3174  O OH  . TYR A 1 393 ? 0.302   -8.098  -32.216 1.00 35.08  ? 393 TYR A OH  1 
ATOM   3175  N N   . THR A 1 394 ? -3.353  -15.085 -28.269 1.00 25.61  ? 394 THR A N   1 
ATOM   3176  C CA  . THR A 1 394 ? -3.971  -16.388 -28.139 1.00 24.36  ? 394 THR A CA  1 
ATOM   3177  C C   . THR A 1 394 ? -5.330  -16.271 -27.458 1.00 25.61  ? 394 THR A C   1 
ATOM   3178  O O   . THR A 1 394 ? -6.208  -17.115 -27.626 1.00 24.08  ? 394 THR A O   1 
ATOM   3179  C CB  . THR A 1 394 ? -3.022  -17.359 -27.431 1.00 28.58  ? 394 THR A CB  1 
ATOM   3180  O OG1 . THR A 1 394 ? -1.767  -17.338 -28.141 1.00 31.12  ? 394 THR A OG1 1 
ATOM   3181  C CG2 . THR A 1 394 ? -3.595  -18.759 -27.397 1.00 27.92  ? 394 THR A CG2 1 
ATOM   3182  N N   . VAL A 1 395 ? -5.475  -15.273 -26.602 1.00 23.95  ? 395 VAL A N   1 
ATOM   3183  C CA  . VAL A 1 395 ? -6.745  -15.050 -25.941 1.00 23.68  ? 395 VAL A CA  1 
ATOM   3184  C C   . VAL A 1 395 ? -7.798  -14.607 -26.965 1.00 20.54  ? 395 VAL A C   1 
ATOM   3185  O O   . VAL A 1 395 ? -8.914  -15.071 -26.890 1.00 24.25  ? 395 VAL A O   1 
ATOM   3186  C CB  . VAL A 1 395 ? -6.607  -14.020 -24.799 1.00 22.49  ? 395 VAL A CB  1 
ATOM   3187  C CG1 . VAL A 1 395 ? -7.965  -13.619 -24.264 1.00 23.10  ? 395 VAL A CG1 1 
ATOM   3188  C CG2 . VAL A 1 395 ? -5.725  -14.530 -23.675 1.00 22.23  ? 395 VAL A CG2 1 
ATOM   3189  N N   . LEU A 1 396 ? -7.462  -13.704 -27.891 1.00 24.13  ? 396 LEU A N   1 
ATOM   3190  C CA  . LEU A 1 396 ? -8.360  -13.313 -28.983 1.00 24.84  ? 396 LEU A CA  1 
ATOM   3191  C C   . LEU A 1 396 ? -8.800  -14.518 -29.825 1.00 24.81  ? 396 LEU A C   1 
ATOM   3192  O O   . LEU A 1 396 ? -9.978  -14.653 -30.205 1.00 25.19  ? 396 LEU A O   1 
ATOM   3193  C CB  . LEU A 1 396 ? -7.653  -12.273 -29.870 1.00 26.00  ? 396 LEU A CB  1 
ATOM   3194  C CG  . LEU A 1 396 ? -7.378  -10.916 -29.224 1.00 26.78  ? 396 LEU A CG  1 
ATOM   3195  C CD1 . LEU A 1 396 ? -6.691  -9.962  -30.182 1.00 30.47  ? 396 LEU A CD1 1 
ATOM   3196  C CD2 . LEU A 1 396 ? -8.656  -10.306 -28.718 1.00 27.39  ? 396 LEU A CD2 1 
ATOM   3197  N N   . PHE A 1 397 ? -7.833  -15.388 -30.132 1.00 27.36  ? 397 PHE A N   1 
ATOM   3198  C CA  . PHE A 1 397 ? -8.087  -16.657 -30.794 1.00 25.87  ? 397 PHE A CA  1 
ATOM   3199  C C   . PHE A 1 397 ? -9.108  -17.459 -29.993 1.00 25.41  ? 397 PHE A C   1 
ATOM   3200  O O   . PHE A 1 397 ? -10.082 -18.014 -30.528 1.00 26.56  ? 397 PHE A O   1 
ATOM   3201  C CB  . PHE A 1 397 ? -6.750  -17.382 -30.986 1.00 29.71  ? 397 PHE A CB  1 
ATOM   3202  C CG  . PHE A 1 397 ? -6.759  -18.604 -31.865 1.00 33.90  ? 397 PHE A CG  1 
ATOM   3203  C CD1 . PHE A 1 397 ? -7.924  -19.085 -32.452 1.00 40.32  ? 397 PHE A CD1 1 
ATOM   3204  C CD2 . PHE A 1 397 ? -5.559  -19.243 -32.170 1.00 45.26  ? 397 PHE A CD2 1 
ATOM   3205  C CE1 . PHE A 1 397 ? -7.890  -20.182 -33.310 1.00 45.13  ? 397 PHE A CE1 1 
ATOM   3206  C CE2 . PHE A 1 397 ? -5.527  -20.343 -33.023 1.00 48.16  ? 397 PHE A CE2 1 
ATOM   3207  C CZ  . PHE A 1 397 ? -6.693  -20.802 -33.603 1.00 43.19  ? 397 PHE A CZ  1 
ATOM   3208  N N   . GLY A 1 398 ? -8.886  -17.570 -28.680 1.00 25.47  ? 398 GLY A N   1 
ATOM   3209  C CA  . GLY A 1 398 ? -9.794  -18.339 -27.852 1.00 22.04  ? 398 GLY A CA  1 
ATOM   3210  C C   . GLY A 1 398 ? -11.223 -17.797 -27.864 1.00 23.12  ? 398 GLY A C   1 
ATOM   3211  O O   . GLY A 1 398 ? -12.196 -18.562 -27.850 1.00 24.60  ? 398 GLY A O   1 
ATOM   3212  N N   . VAL A 1 399 ? -11.358 -16.477 -27.762 1.00 23.16  ? 399 VAL A N   1 
ATOM   3213  C CA  . VAL A 1 399 ? -12.689 -15.862 -27.730 1.00 24.75  ? 399 VAL A CA  1 
ATOM   3214  C C   . VAL A 1 399 ? -13.439 -16.235 -29.016 1.00 23.75  ? 399 VAL A C   1 
ATOM   3215  O O   . VAL A 1 399 ? -14.579 -16.657 -28.991 1.00 24.11  ? 399 VAL A O   1 
ATOM   3216  C CB  . VAL A 1 399 ? -12.590 -14.335 -27.581 1.00 24.25  ? 399 VAL A CB  1 
ATOM   3217  C CG1 . VAL A 1 399 ? -13.949 -13.652 -27.740 1.00 27.21  ? 399 VAL A CG1 1 
ATOM   3218  C CG2 . VAL A 1 399 ? -11.968 -13.917 -26.246 1.00 26.94  ? 399 VAL A CG2 1 
ATOM   3219  N N   . SER A 1 400 ? -12.761 -16.139 -30.150 1.00 24.92  ? 400 SER A N   1 
ATOM   3220  C CA  . SER A 1 400 ? -13.356 -16.536 -31.423 1.00 29.03  ? 400 SER A CA  1 
ATOM   3221  C C   . SER A 1 400 ? -13.739 -18.021 -31.457 1.00 28.53  ? 400 SER A C   1 
ATOM   3222  O O   . SER A 1 400 ? -14.828 -18.405 -31.860 1.00 27.15  ? 400 SER A O   1 
ATOM   3223  C CB  . SER A 1 400 ? -12.374 -16.220 -32.535 1.00 30.85  ? 400 SER A CB  1 
ATOM   3224  O OG  . SER A 1 400 ? -12.838 -16.745 -33.779 1.00 32.11  ? 400 SER A OG  1 
ATOM   3225  N N   . ARG A 1 401 ? -12.823 -18.887 -31.031 1.00 27.66  ? 401 ARG A N   1 
ATOM   3226  C CA  . ARG A 1 401 ? -13.008 -20.324 -31.152 1.00 28.56  ? 401 ARG A CA  1 
ATOM   3227  C C   . ARG A 1 401 ? -14.132 -20.839 -30.260 1.00 27.54  ? 401 ARG A C   1 
ATOM   3228  O O   . ARG A 1 401 ? -14.678 -21.911 -30.518 1.00 26.86  ? 401 ARG A O   1 
ATOM   3229  C CB  . ARG A 1 401 ? -11.651 -20.989 -30.909 1.00 29.18  ? 401 ARG A CB  1 
ATOM   3230  C CG  . ARG A 1 401 ? -11.605 -22.497 -31.040 1.00 31.13  ? 401 ARG A CG  1 
ATOM   3231  C CD  . ARG A 1 401 ? -12.004 -23.050 -32.396 1.00 33.77  ? 401 ARG A CD  1 
ATOM   3232  N NE  . ARG A 1 401 ? -11.357 -22.419 -33.536 1.00 35.27  ? 401 ARG A NE  1 
ATOM   3233  C CZ  . ARG A 1 401 ? -10.337 -22.924 -34.229 1.00 33.45  ? 401 ARG A CZ  1 
ATOM   3234  N NH1 . ARG A 1 401 ? -9.608  -23.907 -33.724 1.00 34.16  ? 401 ARG A NH1 1 
ATOM   3235  N NH2 . ARG A 1 401 ? -9.964  -22.343 -35.350 1.00 32.51  ? 401 ARG A NH2 1 
ATOM   3236  N N   . ALA A 1 402 ? -14.470 -20.098 -29.200 1.00 27.27  ? 402 ALA A N   1 
ATOM   3237  C CA  . ALA A 1 402 ? -15.625 -20.408 -28.382 1.00 27.28  ? 402 ALA A CA  1 
ATOM   3238  C C   . ALA A 1 402 ? -16.922 -20.519 -29.207 1.00 28.57  ? 402 ALA A C   1 
ATOM   3239  O O   . ALA A 1 402 ? -17.857 -21.225 -28.832 1.00 25.41  ? 402 ALA A O   1 
ATOM   3240  C CB  . ALA A 1 402 ? -15.772 -19.323 -27.344 1.00 26.73  ? 402 ALA A CB  1 
ATOM   3241  N N   . LEU A 1 403 ? -17.022 -19.765 -30.297 1.00 27.44  ? 403 LEU A N   1 
ATOM   3242  C CA  . LEU A 1 403 ? -18.201 -19.829 -31.159 1.00 26.45  ? 403 LEU A CA  1 
ATOM   3243  C C   . LEU A 1 403 ? -18.372 -21.235 -31.743 1.00 26.25  ? 403 LEU A C   1 
ATOM   3244  O O   . LEU A 1 403 ? -19.446 -21.804 -31.675 1.00 27.71  ? 403 LEU A O   1 
ATOM   3245  C CB  . LEU A 1 403 ? -18.038 -18.827 -32.293 1.00 27.44  ? 403 LEU A CB  1 
ATOM   3246  C CG  . LEU A 1 403 ? -18.024 -17.367 -31.848 1.00 34.28  ? 403 LEU A CG  1 
ATOM   3247  C CD1 . LEU A 1 403 ? -17.427 -16.515 -32.936 1.00 33.43  ? 403 LEU A CD1 1 
ATOM   3248  C CD2 . LEU A 1 403 ? -19.416 -16.887 -31.440 1.00 33.34  ? 403 LEU A CD2 1 
ATOM   3249  N N   . GLY A 1 404 ? -17.308 -21.809 -32.295 1.00 30.19  ? 404 GLY A N   1 
ATOM   3250  C CA  . GLY A 1 404 ? -17.336 -23.191 -32.788 1.00 29.76  ? 404 GLY A CA  1 
ATOM   3251  C C   . GLY A 1 404 ? -17.508 -24.227 -31.683 1.00 29.84  ? 404 GLY A C   1 
ATOM   3252  O O   . GLY A 1 404 ? -18.287 -25.187 -31.798 1.00 26.25  ? 404 GLY A O   1 
ATOM   3253  N N   . CYS A 1 405 ? -16.785 -24.031 -30.575 1.00 28.68  ? 405 CYS A N   1 
ATOM   3254  C CA  . CYS A 1 405 ? -16.821 -25.012 -29.505 1.00 28.19  ? 405 CYS A CA  1 
ATOM   3255  C C   . CYS A 1 405 ? -18.210 -25.079 -28.900 1.00 26.88  ? 405 CYS A C   1 
ATOM   3256  O O   . CYS A 1 405 ? -18.660 -26.166 -28.561 1.00 28.27  ? 405 CYS A O   1 
ATOM   3257  C CB  . CYS A 1 405 ? -15.803 -24.749 -28.395 1.00 32.36  ? 405 CYS A CB  1 
ATOM   3258  S SG  . CYS A 1 405 ? -14.098 -25.093 -28.923 1.00 38.84  ? 405 CYS A SG  1 
ATOM   3259  N N   . THR A 1 406 ? -18.849 -23.926 -28.700 1.00 25.53  ? 406 THR A N   1 
ATOM   3260  C CA  . THR A 1 406 ? -20.176 -23.935 -28.090 1.00 27.02  ? 406 THR A CA  1 
ATOM   3261  C C   . THR A 1 406 ? -21.170 -24.566 -29.080 1.00 27.55  ? 406 THR A C   1 
ATOM   3262  O O   . THR A 1 406 ? -22.009 -25.334 -28.674 1.00 26.20  ? 406 THR A O   1 
ATOM   3263  C CB  . THR A 1 406 ? -20.647 -22.545 -27.654 1.00 26.73  ? 406 THR A CB  1 
ATOM   3264  O OG1 . THR A 1 406 ? -20.615 -21.657 -28.769 1.00 27.28  ? 406 THR A OG1 1 
ATOM   3265  C CG2 . THR A 1 406 ? -19.802 -21.930 -26.544 1.00 28.55  ? 406 THR A CG2 1 
ATOM   3266  N N   . ALA A 1 407 ? -21.066 -24.230 -30.380 1.00 31.29  ? 407 ALA A N   1 
ATOM   3267  C CA  . ALA A 1 407 ? -21.968 -24.803 -31.378 1.00 29.46  ? 407 ALA A CA  1 
ATOM   3268  C C   . ALA A 1 407 ? -21.817 -26.321 -31.389 1.00 30.74  ? 407 ALA A C   1 
ATOM   3269  O O   . ALA A 1 407 ? -22.796 -27.048 -31.253 1.00 29.69  ? 407 ALA A O   1 
ATOM   3270  C CB  . ALA A 1 407 ? -21.687 -24.213 -32.710 1.00 28.38  ? 407 ALA A CB  1 
ATOM   3271  N N   . GLN A 1 408 ? -20.578 -26.801 -31.411 1.00 29.81  ? 408 GLN A N   1 
ATOM   3272  C CA  . GLN A 1 408 ? -20.358 -28.235 -31.395 1.00 30.56  ? 408 GLN A CA  1 
ATOM   3273  C C   . GLN A 1 408 ? -20.901 -28.889 -30.138 1.00 31.59  ? 408 GLN A C   1 
ATOM   3274  O O   . GLN A 1 408 ? -21.463 -29.970 -30.235 1.00 30.44  ? 408 GLN A O   1 
ATOM   3275  C CB  . GLN A 1 408 ? -18.895 -28.580 -31.578 1.00 30.93  ? 408 GLN A CB  1 
ATOM   3276  C CG  . GLN A 1 408 ? -18.384 -28.212 -32.958 1.00 35.73  ? 408 GLN A CG  1 
ATOM   3277  C CD  . GLN A 1 408 ? -16.950 -28.673 -33.086 1.00 42.78  ? 408 GLN A CD  1 
ATOM   3278  O OE1 . GLN A 1 408 ? -16.581 -29.706 -32.525 1.00 51.98  ? 408 GLN A OE1 1 
ATOM   3279  N NE2 . GLN A 1 408 ? -16.138 -27.909 -33.798 1.00 40.19  ? 408 GLN A NE2 1 
ATOM   3280  N N   . ALA A 1 409 ? -20.710 -28.289 -28.960 1.00 32.14  ? 409 ALA A N   1 
ATOM   3281  C CA  . ALA A 1 409 ? -21.114 -28.957 -27.730 1.00 31.21  ? 409 ALA A CA  1 
ATOM   3282  C C   . ALA A 1 409 ? -22.640 -29.041 -27.636 1.00 32.10  ? 409 ALA A C   1 
ATOM   3283  O O   . ALA A 1 409 ? -23.212 -29.998 -27.103 1.00 30.27  ? 409 ALA A O   1 
ATOM   3284  C CB  . ALA A 1 409 ? -20.567 -28.201 -26.536 1.00 32.74  ? 409 ALA A CB  1 
ATOM   3285  N N   . ILE A 1 410 ? -23.317 -27.993 -28.091 1.00 30.59  ? 410 ILE A N   1 
ATOM   3286  C CA  . ILE A 1 410 ? -24.771 -28.012 -28.098 1.00 30.85  ? 410 ILE A CA  1 
ATOM   3287  C C   . ILE A 1 410 ? -25.260 -29.146 -29.015 1.00 29.67  ? 410 ILE A C   1 
ATOM   3288  O O   . ILE A 1 410 ? -26.107 -29.943 -28.644 1.00 30.39  ? 410 ILE A O   1 
ATOM   3289  C CB  . ILE A 1 410 ? -25.304 -26.632 -28.529 1.00 31.93  ? 410 ILE A CB  1 
ATOM   3290  C CG1 . ILE A 1 410 ? -24.976 -25.524 -27.519 1.00 31.08  ? 410 ILE A CG1 1 
ATOM   3291  C CG2 . ILE A 1 410 ? -26.798 -26.717 -28.764 1.00 35.30  ? 410 ILE A CG2 1 
ATOM   3292  C CD1 . ILE A 1 410 ? -25.055 -24.133 -28.091 1.00 33.45  ? 410 ILE A CD1 1 
ATOM   3293  N N   . LEU A 1 411 ? -24.686 -29.236 -30.211 1.00 31.40  ? 411 LEU A N   1 
ATOM   3294  C CA  . LEU A 1 411 ? -25.148 -30.172 -31.216 1.00 33.71  ? 411 LEU A CA  1 
ATOM   3295  C C   . LEU A 1 411 ? -24.929 -31.604 -30.746 1.00 36.88  ? 411 LEU A C   1 
ATOM   3296  O O   . LEU A 1 411 ? -25.848 -32.423 -30.789 1.00 31.38  ? 411 LEU A O   1 
ATOM   3297  C CB  . LEU A 1 411 ? -24.432 -29.865 -32.534 1.00 32.09  ? 411 LEU A CB  1 
ATOM   3298  C CG  . LEU A 1 411 ? -24.938 -28.605 -33.228 1.00 37.11  ? 411 LEU A CG  1 
ATOM   3299  C CD1 . LEU A 1 411 ? -24.162 -28.349 -34.505 1.00 38.10  ? 411 LEU A CD1 1 
ATOM   3300  C CD2 . LEU A 1 411 ? -26.434 -28.725 -33.515 1.00 40.24  ? 411 LEU A CD2 1 
ATOM   3301  N N   . VAL A 1 412 ? -23.721 -31.895 -30.246 1.00 34.04  ? 412 VAL A N   1 
ATOM   3302  C CA  . VAL A 1 412 ? -23.384 -33.260 -29.879 1.00 33.16  ? 412 VAL A CA  1 
ATOM   3303  C C   . VAL A 1 412 ? -24.271 -33.708 -28.709 1.00 32.11  ? 412 VAL A C   1 
ATOM   3304  O O   . VAL A 1 412 ? -24.622 -34.897 -28.572 1.00 30.08  ? 412 VAL A O   1 
ATOM   3305  C CB  . VAL A 1 412 ? -21.853 -33.344 -29.674 1.00 42.30  ? 412 VAL A CB  1 
ATOM   3306  C CG1 . VAL A 1 412 ? -21.424 -34.376 -28.653 1.00 54.86  ? 412 VAL A CG1 1 
ATOM   3307  C CG2 . VAL A 1 412 ? -21.159 -33.567 -31.013 1.00 42.10  ? 412 VAL A CG2 1 
ATOM   3308  N N   . ARG A 1 413 ? -24.662 -32.769 -27.845 1.00 30.06  ? 413 ARG A N   1 
ATOM   3309  C CA  . ARG A 1 413 ? -25.564 -33.106 -26.753 1.00 33.11  ? 413 ARG A CA  1 
ATOM   3310  C C   . ARG A 1 413 ? -27.008 -33.285 -27.266 1.00 36.80  ? 413 ARG A C   1 
ATOM   3311  O O   . ARG A 1 413 ? -27.772 -34.086 -26.704 1.00 37.22  ? 413 ARG A O   1 
ATOM   3312  C CB  . ARG A 1 413 ? -25.440 -32.095 -25.616 1.00 35.40  ? 413 ARG A CB  1 
ATOM   3313  C CG  . ARG A 1 413 ? -24.038 -32.017 -25.007 1.00 37.28  ? 413 ARG A CG  1 
ATOM   3314  C CD  . ARG A 1 413 ? -23.719 -32.970 -23.870 1.00 39.26  ? 413 ARG A CD  1 
ATOM   3315  N NE  . ARG A 1 413 ? -24.148 -34.341 -24.063 1.00 42.59  ? 413 ARG A NE  1 
ATOM   3316  C CZ  . ARG A 1 413 ? -23.552 -35.254 -24.827 1.00 39.69  ? 413 ARG A CZ  1 
ATOM   3317  N NH1 . ARG A 1 413 ? -22.350 -35.050 -25.332 1.00 37.45  ? 413 ARG A NH1 1 
ATOM   3318  N NH2 . ARG A 1 413 ? -24.182 -36.386 -25.086 1.00 40.03  ? 413 ARG A NH2 1 
ATOM   3319  N N   . GLY A 1 414 ? -27.374 -32.557 -28.329 1.00 33.91  ? 414 GLY A N   1 
ATOM   3320  C CA  . GLY A 1 414 ? -28.619 -32.778 -29.060 1.00 35.52  ? 414 GLY A CA  1 
ATOM   3321  C C   . GLY A 1 414 ? -28.679 -34.164 -29.715 1.00 36.13  ? 414 GLY A C   1 
ATOM   3322  O O   . GLY A 1 414 ? -29.676 -34.879 -29.564 1.00 41.50  ? 414 GLY A O   1 
ATOM   3323  N N   . TYR A 1 415 ? -27.574 -34.567 -30.367 1.00 36.57  ? 415 TYR A N   1 
ATOM   3324  C CA  . TYR A 1 415 ? -27.434 -35.883 -30.971 1.00 38.76  ? 415 TYR A CA  1 
ATOM   3325  C C   . TYR A 1 415 ? -27.356 -37.003 -29.939 1.00 39.61  ? 415 TYR A C   1 
ATOM   3326  O O   . TYR A 1 415 ? -27.581 -38.160 -30.269 1.00 40.07  ? 415 TYR A O   1 
ATOM   3327  C CB  . TYR A 1 415 ? -26.158 -36.026 -31.799 1.00 36.86  ? 415 TYR A CB  1 
ATOM   3328  C CG  . TYR A 1 415 ? -25.962 -35.103 -32.966 1.00 34.62  ? 415 TYR A CG  1 
ATOM   3329  C CD1 . TYR A 1 415 ? -26.897 -34.150 -33.352 1.00 40.18  ? 415 TYR A CD1 1 
ATOM   3330  C CD2 . TYR A 1 415 ? -24.761 -35.127 -33.633 1.00 34.75  ? 415 TYR A CD2 1 
ATOM   3331  C CE1 . TYR A 1 415 ? -26.649 -33.291 -34.413 1.00 40.39  ? 415 TYR A CE1 1 
ATOM   3332  C CE2 . TYR A 1 415 ? -24.483 -34.255 -34.659 1.00 38.07  ? 415 TYR A CE2 1 
ATOM   3333  C CZ  . TYR A 1 415 ? -25.431 -33.338 -35.067 1.00 40.38  ? 415 TYR A CZ  1 
ATOM   3334  O OH  . TYR A 1 415 ? -25.069 -32.535 -36.131 1.00 43.14  ? 415 TYR A OH  1 
ATOM   3335  N N   . MET A 1 416 ? -26.919 -36.689 -28.718 1.00 41.47  ? 416 MET A N   1 
ATOM   3336  C CA  . MET A 1 416 ? -26.763 -37.673 -27.652 1.00 36.97  ? 416 MET A CA  1 
ATOM   3337  C C   . MET A 1 416 ? -25.642 -38.676 -27.947 1.00 33.54  ? 416 MET A C   1 
ATOM   3338  O O   . MET A 1 416 ? -25.734 -39.829 -27.568 1.00 34.65  ? 416 MET A O   1 
ATOM   3339  C CB  . MET A 1 416 ? -28.062 -38.444 -27.390 1.00 40.28  ? 416 MET A CB  1 
ATOM   3340  C CG  . MET A 1 416 ? -29.104 -37.573 -26.727 1.00 46.84  ? 416 MET A CG  1 
ATOM   3341  S SD  . MET A 1 416 ? -30.699 -38.388 -26.680 1.00 57.48  ? 416 MET A SD  1 
ATOM   3342  C CE  . MET A 1 416 ? -31.689 -37.004 -26.112 1.00 60.80  ? 416 MET A CE  1 
ATOM   3343  N N   . LEU A 1 417 ? -24.521 -38.215 -28.492 1.00 33.40  ? 417 LEU A N   1 
ATOM   3344  C CA  . LEU A 1 417 ? -23.354 -39.068 -28.610 1.00 32.84  ? 417 LEU A CA  1 
ATOM   3345  C C   . LEU A 1 417 ? -22.793 -39.484 -27.243 1.00 36.94  ? 417 LEU A C   1 
ATOM   3346  O O   . LEU A 1 417 ? -22.916 -38.793 -26.224 1.00 34.53  ? 417 LEU A O   1 
ATOM   3347  C CB  . LEU A 1 417 ? -22.310 -38.338 -29.440 1.00 34.93  ? 417 LEU A CB  1 
ATOM   3348  C CG  . LEU A 1 417 ? -22.744 -37.957 -30.851 1.00 39.97  ? 417 LEU A CG  1 
ATOM   3349  C CD1 . LEU A 1 417 ? -21.519 -37.658 -31.685 1.00 39.46  ? 417 LEU A CD1 1 
ATOM   3350  C CD2 . LEU A 1 417 ? -23.626 -39.041 -31.495 1.00 37.18  ? 417 LEU A CD2 1 
ATOM   3351  N N   . PRO A 1 418 ? -22.163 -40.671 -27.175 1.00 33.50  ? 418 PRO A N   1 
ATOM   3352  C CA  . PRO A 1 418 ? -21.669 -41.189 -25.912 1.00 35.19  ? 418 PRO A CA  1 
ATOM   3353  C C   . PRO A 1 418 ? -20.281 -40.645 -25.586 1.00 34.10  ? 418 PRO A C   1 
ATOM   3354  O O   . PRO A 1 418 ? -19.682 -39.891 -26.354 1.00 35.24  ? 418 PRO A O   1 
ATOM   3355  C CB  . PRO A 1 418 ? -21.653 -42.703 -26.197 1.00 37.63  ? 418 PRO A CB  1 
ATOM   3356  C CG  . PRO A 1 418 ? -21.208 -42.771 -27.649 1.00 37.94  ? 418 PRO A CG  1 
ATOM   3357  C CD  . PRO A 1 418 ? -21.944 -41.610 -28.291 1.00 38.59  ? 418 PRO A CD  1 
ATOM   3358  N N   . ILE A 1 419 ? -19.757 -41.155 -24.480 1.00 38.07  ? 419 ILE A N   1 
ATOM   3359  C CA  . ILE A 1 419 ? -18.491 -40.753 -23.909 1.00 34.12  ? 419 ILE A CA  1 
ATOM   3360  C C   . ILE A 1 419 ? -17.376 -41.161 -24.856 1.00 33.36  ? 419 ILE A C   1 
ATOM   3361  O O   . ILE A 1 419 ? -17.446 -42.178 -25.515 1.00 32.00  ? 419 ILE A O   1 
ATOM   3362  C CB  . ILE A 1 419 ? -18.401 -41.333 -22.475 1.00 35.24  ? 419 ILE A CB  1 
ATOM   3363  C CG1 . ILE A 1 419 ? -17.226 -40.738 -21.702 1.00 34.50  ? 419 ILE A CG1 1 
ATOM   3364  C CG2 . ILE A 1 419 ? -18.365 -42.857 -22.433 1.00 33.25  ? 419 ILE A CG2 1 
ATOM   3365  C CD1 . ILE A 1 419 ? -17.246 -41.092 -20.231 1.00 35.62  ? 419 ILE A CD1 1 
ATOM   3366  N N   . GLU A 1 420 ? -16.390 -40.290 -25.031 1.00 29.99  ? 420 GLU A N   1 
ATOM   3367  C CA  . GLU A 1 420 ? -15.251 -40.630 -25.848 1.00 30.83  ? 420 GLU A CA  1 
ATOM   3368  C C   . GLU A 1 420 ? -14.295 -41.487 -25.019 1.00 36.50  ? 420 GLU A C   1 
ATOM   3369  O O   . GLU A 1 420 ? -13.848 -41.058 -23.951 1.00 34.02  ? 420 GLU A O   1 
ATOM   3370  C CB  . GLU A 1 420 ? -14.613 -39.347 -26.364 1.00 32.14  ? 420 GLU A CB  1 
ATOM   3371  C CG  . GLU A 1 420 ? -13.426 -39.595 -27.259 1.00 39.55  ? 420 GLU A CG  1 
ATOM   3372  C CD  . GLU A 1 420 ? -12.812 -38.344 -27.870 1.00 46.22  ? 420 GLU A CD  1 
ATOM   3373  O OE1 . GLU A 1 420 ? -11.615 -38.409 -28.156 1.00 46.14  ? 420 GLU A OE1 1 
ATOM   3374  O OE2 . GLU A 1 420 ? -13.537 -37.322 -28.081 1.00 43.57  ? 420 GLU A OE2 1 
ATOM   3375  N N   . ARG A 1 421 ? -13.963 -42.687 -25.529 1.00 33.74  ? 421 ARG A N   1 
ATOM   3376  C CA  . ARG A 1 421 ? -13.204 -43.678 -24.779 1.00 42.39  ? 421 ARG A CA  1 
ATOM   3377  C C   . ARG A 1 421 ? -12.460 -44.615 -25.741 1.00 37.17  ? 421 ARG A C   1 
ATOM   3378  O O   . ARG A 1 421 ? -12.849 -45.740 -25.964 1.00 36.17  ? 421 ARG A O   1 
ATOM   3379  C CB  . ARG A 1 421 ? -14.152 -44.451 -23.858 1.00 47.79  ? 421 ARG A CB  1 
ATOM   3380  C CG  . ARG A 1 421 ? -13.544 -44.870 -22.527 1.00 62.87  ? 421 ARG A CG  1 
ATOM   3381  C CD  . ARG A 1 421 ? -14.545 -45.680 -21.713 1.00 82.85  ? 421 ARG A CD  1 
ATOM   3382  N NE  . ARG A 1 421 ? -14.720 -47.039 -22.228 1.00 96.00  ? 421 ARG A NE  1 
ATOM   3383  C CZ  . ARG A 1 421 ? -15.459 -47.987 -21.654 1.00 94.41  ? 421 ARG A CZ  1 
ATOM   3384  N NH1 . ARG A 1 421 ? -16.048 -47.745 -20.498 1.00 80.92  ? 421 ARG A NH1 1 
ATOM   3385  N NH2 . ARG A 1 421 ? -15.593 -49.177 -22.227 1.00 93.95  ? 421 ARG A NH2 1 
ATOM   3386  N N   . PRO A 1 422 ? -11.372 -44.177 -26.384 1.00 34.51  ? 422 PRO A N   1 
ATOM   3387  C CA  . PRO A 1 422 ? -10.574 -45.057 -27.221 1.00 33.00  ? 422 PRO A CA  1 
ATOM   3388  C C   . PRO A 1 422 ? -9.773  -46.014 -26.348 1.00 36.83  ? 422 PRO A C   1 
ATOM   3389  O O   . PRO A 1 422 ? -9.809  -45.948 -25.121 1.00 35.47  ? 422 PRO A O   1 
ATOM   3390  C CB  . PRO A 1 422 ? -9.622  -44.135 -28.001 1.00 36.64  ? 422 PRO A CB  1 
ATOM   3391  C CG  . PRO A 1 422 ? -9.609  -42.808 -27.211 1.00 37.12  ? 422 PRO A CG  1 
ATOM   3392  C CD  . PRO A 1 422 ? -10.839 -42.806 -26.321 1.00 37.23  ? 422 PRO A CD  1 
ATOM   3393  N N   . LYS A 1 423 ? -9.058  -46.908 -27.026 1.00 33.71  ? 423 LYS A N   1 
ATOM   3394  C CA  . LYS A 1 423 ? -8.217  -47.915 -26.406 1.00 34.74  ? 423 LYS A CA  1 
ATOM   3395  C C   . LYS A 1 423 ? -6.775  -47.480 -26.594 1.00 36.13  ? 423 LYS A C   1 
ATOM   3396  O O   . LYS A 1 423 ? -6.362  -47.117 -27.696 1.00 36.01  ? 423 LYS A O   1 
ATOM   3397  C CB  . LYS A 1 423 ? -8.504  -49.255 -27.095 1.00 43.87  ? 423 LYS A CB  1 
ATOM   3398  C CG  . LYS A 1 423 ? -7.681  -50.439 -26.627 1.00 51.48  ? 423 LYS A CG  1 
ATOM   3399  C CD  . LYS A 1 423 ? -7.941  -50.831 -25.196 1.00 52.77  ? 423 LYS A CD  1 
ATOM   3400  C CE  . LYS A 1 423 ? -6.998  -51.935 -24.756 1.00 52.75  ? 423 LYS A CE  1 
ATOM   3401  N NZ  . LYS A 1 423 ? -7.134  -52.205 -23.307 1.00 53.79  ? 423 LYS A NZ  1 
ATOM   3402  N N   . SER A 1 424 ? -5.999  -47.534 -25.509 1.00 35.89  ? 424 SER A N   1 
ATOM   3403  C CA  . SER A 1 424 ? -4.574  -47.312 -25.613 1.00 35.87  ? 424 SER A CA  1 
ATOM   3404  C C   . SER A 1 424 ? -3.912  -48.665 -25.857 1.00 31.81  ? 424 SER A C   1 
ATOM   3405  O O   . SER A 1 424 ? -4.419  -49.685 -25.425 1.00 32.23  ? 424 SER A O   1 
ATOM   3406  C CB  . SER A 1 424 ? -4.023  -46.583 -24.379 1.00 36.31  ? 424 SER A CB  1 
ATOM   3407  O OG  . SER A 1 424 ? -4.365  -47.285 -23.190 1.00 36.91  ? 424 SER A OG  1 
ATOM   3408  N N   . ILE A 1 425 ? -2.778  -48.666 -26.563 1.00 34.96  ? 425 ILE A N   1 
ATOM   3409  C CA  . ILE A 1 425 ? -1.963  -49.869 -26.698 1.00 36.26  ? 425 ILE A CA  1 
ATOM   3410  C C   . ILE A 1 425 ? -0.600  -49.616 -26.067 1.00 37.38  ? 425 ILE A C   1 
ATOM   3411  O O   . ILE A 1 425 ? -0.150  -48.470 -25.955 1.00 34.48  ? 425 ILE A O   1 
ATOM   3412  C CB  . ILE A 1 425 ? -1.800  -50.270 -28.189 1.00 35.63  ? 425 ILE A CB  1 
ATOM   3413  C CG1 . ILE A 1 425 ? -1.022  -49.215 -28.975 1.00 40.28  ? 425 ILE A CG1 1 
ATOM   3414  C CG2 . ILE A 1 425 ? -3.144  -50.562 -28.830 1.00 39.22  ? 425 ILE A CG2 1 
ATOM   3415  C CD1 . ILE A 1 425 ? -0.923  -49.479 -30.484 1.00 44.53  ? 425 ILE A CD1 1 
ATOM   3416  N N   . THR A 1 426 ? 0.122   -50.709 -25.805 1.00 37.59  ? 426 THR A N   1 
ATOM   3417  C CA  . THR A 1 426 ? 1.448   -50.635 -25.227 1.00 35.88  ? 426 THR A CA  1 
ATOM   3418  C C   . THR A 1 426 ? 2.523   -50.946 -26.258 1.00 37.64  ? 426 THR A C   1 
ATOM   3419  O O   . THR A 1 426 ? 2.292   -51.730 -27.177 1.00 34.07  ? 426 THR A O   1 
ATOM   3420  C CB  . THR A 1 426 ? 1.632   -51.655 -24.096 1.00 38.64  ? 426 THR A CB  1 
ATOM   3421  O OG1 . THR A 1 426 ? 1.435   -52.992 -24.592 1.00 35.10  ? 426 THR A OG1 1 
ATOM   3422  C CG2 . THR A 1 426 ? 0.744   -51.341 -22.915 1.00 36.06  ? 426 THR A CG2 1 
ATOM   3423  N N   . THR A 1 427 ? 3.714   -50.392 -26.025 1.00 32.30  ? 427 THR A N   1 
ATOM   3424  C CA  . THR A 1 427 ? 4.878   -50.730 -26.815 1.00 39.65  ? 427 THR A CA  1 
ATOM   3425  C C   . THR A 1 427 ? 5.201   -52.229 -26.663 1.00 42.21  ? 427 THR A C   1 
ATOM   3426  O O   . THR A 1 427 ? 5.604   -52.860 -27.651 1.00 38.54  ? 427 THR A O   1 
ATOM   3427  C CB  . THR A 1 427 ? 6.030   -49.790 -26.464 1.00 37.91  ? 427 THR A CB  1 
ATOM   3428  O OG1 . THR A 1 427 ? 5.504   -48.472 -26.642 1.00 36.18  ? 427 THR A OG1 1 
ATOM   3429  C CG2 . THR A 1 427 ? 7.267   -50.001 -27.316 1.00 37.52  ? 427 THR A CG2 1 
ATOM   3430  N N   . ARG A 1 428 ? 5.019   -52.786 -25.450 1.00 36.37  ? 428 ARG A N   1 
ATOM   3431  C CA  . ARG A 1 428 ? 5.283   -54.195 -25.179 1.00 40.02  ? 428 ARG A CA  1 
ATOM   3432  C C   . ARG A 1 428 ? 4.464   -55.031 -26.157 1.00 41.38  ? 428 ARG A C   1 
ATOM   3433  O O   . ARG A 1 428 ? 5.005   -55.928 -26.798 1.00 37.58  ? 428 ARG A O   1 
ATOM   3434  C CB  . ARG A 1 428 ? 4.966   -54.606 -23.731 1.00 39.34  ? 428 ARG A CB  1 
ATOM   3435  C CG  . ARG A 1 428 ? 5.276   -56.064 -23.391 1.00 38.47  ? 428 ARG A CG  1 
ATOM   3436  C CD  . ARG A 1 428 ? 4.257   -56.695 -22.431 1.00 38.81  ? 428 ARG A CD  1 
ATOM   3437  N NE  . ARG A 1 428 ? 2.875   -56.477 -22.883 1.00 45.78  ? 428 ARG A NE  1 
ATOM   3438  C CZ  . ARG A 1 428 ? 2.187   -57.291 -23.700 1.00 46.69  ? 428 ARG A CZ  1 
ATOM   3439  N NH1 . ARG A 1 428 ? 2.736   -58.410 -24.147 1.00 45.97  ? 428 ARG A NH1 1 
ATOM   3440  N NH2 . ARG A 1 428 ? 0.954   -56.992 -24.082 1.00 39.01  ? 428 ARG A NH2 1 
ATOM   3441  N N   . TRP A 1 429 ? 3.190   -54.676 -26.320 1.00 35.38  ? 429 TRP A N   1 
ATOM   3442  C CA  . TRP A 1 429 ? 2.296   -55.413 -27.201 1.00 36.40  ? 429 TRP A CA  1 
ATOM   3443  C C   . TRP A 1 429 ? 2.673   -55.226 -28.673 1.00 40.69  ? 429 TRP A C   1 
ATOM   3444  O O   . TRP A 1 429 ? 2.708   -56.190 -29.437 1.00 38.39  ? 429 TRP A O   1 
ATOM   3445  C CB  . TRP A 1 429 ? 0.871   -54.955 -26.959 1.00 37.06  ? 429 TRP A CB  1 
ATOM   3446  C CG  . TRP A 1 429 ? -0.162  -55.638 -27.782 1.00 38.66  ? 429 TRP A CG  1 
ATOM   3447  C CD1 . TRP A 1 429 ? -0.715  -56.863 -27.551 1.00 39.66  ? 429 TRP A CD1 1 
ATOM   3448  C CD2 . TRP A 1 429 ? -0.774  -55.129 -28.976 1.00 35.17  ? 429 TRP A CD2 1 
ATOM   3449  N NE1 . TRP A 1 429 ? -1.645  -57.140 -28.514 1.00 43.65  ? 429 TRP A NE1 1 
ATOM   3450  C CE2 . TRP A 1 429 ? -1.699  -56.105 -29.405 1.00 35.46  ? 429 TRP A CE2 1 
ATOM   3451  C CE3 . TRP A 1 429 ? -0.637  -53.953 -29.720 1.00 35.94  ? 429 TRP A CE3 1 
ATOM   3452  C CZ2 . TRP A 1 429 ? -2.479  -55.942 -30.542 1.00 37.34  ? 429 TRP A CZ2 1 
ATOM   3453  C CZ3 . TRP A 1 429 ? -1.413  -53.789 -30.845 1.00 40.77  ? 429 TRP A CZ3 1 
ATOM   3454  C CH2 . TRP A 1 429 ? -2.336  -54.765 -31.239 1.00 36.16  ? 429 TRP A CH2 1 
ATOM   3455  N N   . VAL A 1 430 ? 2.882   -53.970 -29.081 1.00 32.31  ? 430 VAL A N   1 
ATOM   3456  C CA  . VAL A 1 430 ? 3.400   -53.654 -30.407 1.00 39.62  ? 430 VAL A CA  1 
ATOM   3457  C C   . VAL A 1 430 ? 4.631   -54.513 -30.733 1.00 37.75  ? 430 VAL A C   1 
ATOM   3458  O O   . VAL A 1 430 ? 4.674   -55.093 -31.792 1.00 39.97  ? 430 VAL A O   1 
ATOM   3459  C CB  . VAL A 1 430 ? 3.739   -52.162 -30.574 1.00 39.65  ? 430 VAL A CB  1 
ATOM   3460  C CG1 . VAL A 1 430 ? 4.512   -51.898 -31.858 1.00 38.33  ? 430 VAL A CG1 1 
ATOM   3461  C CG2 . VAL A 1 430 ? 2.496   -51.288 -30.514 1.00 40.17  ? 430 VAL A CG2 1 
ATOM   3462  N N   . LYS A 1 431 ? 5.619   -54.610 -29.844 1.00 38.41  ? 431 LYS A N   1 
ATOM   3463  C CA  . LYS A 1 431 ? 6.810   -55.403 -30.112 1.00 38.71  ? 431 LYS A CA  1 
ATOM   3464  C C   . LYS A 1 431 ? 6.449   -56.880 -30.254 1.00 46.15  ? 431 LYS A C   1 
ATOM   3465  O O   . LYS A 1 431 ? 7.009   -57.574 -31.089 1.00 46.66  ? 431 LYS A O   1 
ATOM   3466  C CB  . LYS A 1 431 ? 7.861   -55.304 -29.006 1.00 38.73  ? 431 LYS A CB  1 
ATOM   3467  C CG  . LYS A 1 431 ? 8.587   -53.969 -28.877 1.00 45.37  ? 431 LYS A CG  1 
ATOM   3468  C CD  . LYS A 1 431 ? 9.810   -54.084 -27.992 1.00 49.14  ? 431 LYS A CD  1 
ATOM   3469  C CE  . LYS A 1 431 ? 10.063  -52.821 -27.212 1.00 63.67  ? 431 LYS A CE  1 
ATOM   3470  N NZ  . LYS A 1 431 ? 11.173  -52.998 -26.248 1.00 67.28  ? 431 LYS A NZ  1 
ATOM   3471  N N   . GLU A 1 432 ? 5.504   -57.354 -29.446 1.00 47.15  ? 432 GLU A N   1 
ATOM   3472  C CA  . GLU A 1 432 ? 5.105   -58.751 -29.463 1.00 46.23  ? 432 GLU A CA  1 
ATOM   3473  C C   . GLU A 1 432 ? 4.427   -59.137 -30.781 1.00 47.75  ? 432 GLU A C   1 
ATOM   3474  O O   . GLU A 1 432 ? 4.640   -60.240 -31.259 1.00 40.94  ? 432 GLU A O   1 
ATOM   3475  C CB  . GLU A 1 432 ? 4.160   -59.045 -28.293 1.00 49.89  ? 432 GLU A CB  1 
ATOM   3476  C CG  . GLU A 1 432 ? 3.819   -60.525 -28.138 1.00 57.97  ? 432 GLU A CG  1 
ATOM   3477  C CD  . GLU A 1 432 ? 2.752   -60.947 -27.129 1.00 65.73  ? 432 GLU A CD  1 
ATOM   3478  O OE1 . GLU A 1 432 ? 2.662   -62.163 -26.897 1.00 74.08  ? 432 GLU A OE1 1 
ATOM   3479  O OE2 . GLU A 1 432 ? 1.992   -60.090 -26.588 1.00 64.41  ? 432 GLU A OE2 1 
ATOM   3480  N N   . VAL A 1 433 ? 3.536   -58.305 -31.343 1.00 44.51  ? 433 VAL A N   1 
ATOM   3481  C CA  . VAL A 1 433 ? 2.658   -58.819 -32.382 1.00 43.41  ? 433 VAL A CA  1 
ATOM   3482  C C   . VAL A 1 433 ? 2.848   -58.084 -33.711 1.00 42.36  ? 433 VAL A C   1 
ATOM   3483  O O   . VAL A 1 433 ? 2.182   -58.430 -34.678 1.00 39.42  ? 433 VAL A O   1 
ATOM   3484  C CB  . VAL A 1 433 ? 1.175   -58.747 -31.957 1.00 45.84  ? 433 VAL A CB  1 
ATOM   3485  C CG1 . VAL A 1 433 ? 0.920   -59.336 -30.576 1.00 46.15  ? 433 VAL A CG1 1 
ATOM   3486  C CG2 . VAL A 1 433 ? 0.640   -57.328 -32.048 1.00 45.34  ? 433 VAL A CG2 1 
ATOM   3487  N N   . ALA A 1 434 ? 3.675   -57.036 -33.778 1.00 38.80  ? 434 ALA A N   1 
ATOM   3488  C CA  . ALA A 1 434 ? 3.672   -56.189 -34.965 1.00 39.41  ? 434 ALA A CA  1 
ATOM   3489  C C   . ALA A 1 434 ? 3.969   -57.005 -36.236 1.00 39.71  ? 434 ALA A C   1 
ATOM   3490  O O   . ALA A 1 434 ? 3.265   -56.847 -37.228 1.00 34.46  ? 434 ALA A O   1 
ATOM   3491  C CB  . ALA A 1 434 ? 4.665   -55.074 -34.829 1.00 39.14  ? 434 ALA A CB  1 
ATOM   3492  N N   . GLU A 1 435 ? 5.022   -57.834 -36.200 1.00 39.10  ? 435 GLU A N   1 
ATOM   3493  C CA  . GLU A 1 435 ? 5.436   -58.641 -37.343 1.00 47.65  ? 435 GLU A CA  1 
ATOM   3494  C C   . GLU A 1 435 ? 4.313   -59.534 -37.844 1.00 45.00  ? 435 GLU A C   1 
ATOM   3495  O O   . GLU A 1 435 ? 4.195   -59.717 -39.045 1.00 48.74  ? 435 GLU A O   1 
ATOM   3496  C CB  . GLU A 1 435 ? 6.642   -59.510 -37.010 1.00 45.59  ? 435 GLU A CB  1 
ATOM   3497  C CG  . GLU A 1 435 ? 7.924   -58.704 -37.003 1.00 50.26  ? 435 GLU A CG  1 
ATOM   3498  C CD  . GLU A 1 435 ? 9.060   -59.346 -36.218 1.00 57.47  ? 435 GLU A CD  1 
ATOM   3499  O OE1 . GLU A 1 435 ? 10.141  -59.605 -36.815 1.00 52.46  ? 435 GLU A OE1 1 
ATOM   3500  O OE2 . GLU A 1 435 ? 8.867   -59.557 -34.998 1.00 50.94  ? 435 GLU A OE2 1 
ATOM   3501  N N   . SER A 1 436 ? 3.481   -60.040 -36.935 1.00 42.88  ? 436 SER A N   1 
ATOM   3502  C CA  . SER A 1 436 ? 2.374   -60.902 -37.303 1.00 43.73  ? 436 SER A CA  1 
ATOM   3503  C C   . SER A 1 436 ? 1.171   -60.108 -37.823 1.00 45.83  ? 436 SER A C   1 
ATOM   3504  O O   . SER A 1 436 ? 0.245   -60.729 -38.345 1.00 37.62  ? 436 SER A O   1 
ATOM   3505  C CB  . SER A 1 436 ? 1.985   -61.796 -36.148 1.00 46.76  ? 436 SER A CB  1 
ATOM   3506  O OG  . SER A 1 436 ? 1.145   -61.103 -35.232 1.00 53.64  ? 436 SER A OG  1 
ATOM   3507  N N   . LEU A 1 437 ? 1.163   -58.759 -37.705 1.00 40.02  ? 437 LEU A N   1 
ATOM   3508  C CA  . LEU A 1 437 ? 0.021   -58.010 -38.215 1.00 41.70  ? 437 LEU A CA  1 
ATOM   3509  C C   . LEU A 1 437 ? 0.155   -57.834 -39.721 1.00 35.86  ? 437 LEU A C   1 
ATOM   3510  O O   . LEU A 1 437 ? 1.243   -57.661 -40.256 1.00 40.62  ? 437 LEU A O   1 
ATOM   3511  C CB  . LEU A 1 437 ? -0.111  -56.614 -37.580 1.00 40.23  ? 437 LEU A CB  1 
ATOM   3512  C CG  . LEU A 1 437 ? -0.451  -56.544 -36.092 1.00 43.89  ? 437 LEU A CG  1 
ATOM   3513  C CD1 . LEU A 1 437 ? -0.414  -55.094 -35.637 1.00 44.39  ? 437 LEU A CD1 1 
ATOM   3514  C CD2 . LEU A 1 437 ? -1.799  -57.188 -35.777 1.00 43.09  ? 437 LEU A CD2 1 
ATOM   3515  N N   . PRO A 1 438 ? -0.974  -57.703 -40.429 1.00 39.47  ? 438 PRO A N   1 
ATOM   3516  C CA  . PRO A 1 438 ? -0.936  -57.303 -41.836 1.00 44.85  ? 438 PRO A CA  1 
ATOM   3517  C C   . PRO A 1 438 ? -0.586  -55.831 -42.059 1.00 44.65  ? 438 PRO A C   1 
ATOM   3518  O O   . PRO A 1 438 ? -0.914  -54.959 -41.254 1.00 42.28  ? 438 PRO A O   1 
ATOM   3519  C CB  . PRO A 1 438 ? -2.358  -57.641 -42.309 1.00 45.99  ? 438 PRO A CB  1 
ATOM   3520  C CG  . PRO A 1 438 ? -3.229  -57.525 -41.068 1.00 43.47  ? 438 PRO A CG  1 
ATOM   3521  C CD  . PRO A 1 438 ? -2.332  -57.928 -39.919 1.00 43.08  ? 438 PRO A CD  1 
ATOM   3522  N N   . VAL A 1 439 ? 0.129   -55.572 -43.150 1.00 44.00  ? 439 VAL A N   1 
ATOM   3523  C CA  . VAL A 1 439 ? 0.339   -54.229 -43.657 1.00 45.57  ? 439 VAL A CA  1 
ATOM   3524  C C   . VAL A 1 439 ? -0.995  -53.714 -44.196 1.00 52.53  ? 439 VAL A C   1 
ATOM   3525  O O   . VAL A 1 439 ? -1.751  -54.489 -44.786 1.00 47.71  ? 439 VAL A O   1 
ATOM   3526  C CB  . VAL A 1 439 ? 1.447   -54.236 -44.721 1.00 47.64  ? 439 VAL A CB  1 
ATOM   3527  C CG1 . VAL A 1 439 ? 1.670   -52.869 -45.340 1.00 52.11  ? 439 VAL A CG1 1 
ATOM   3528  C CG2 . VAL A 1 439 ? 2.743   -54.758 -44.125 1.00 53.39  ? 439 VAL A CG2 1 
ATOM   3529  N N   . ALA A 1 440 ? -1.304  -52.428 -43.943 1.00 46.96  ? 440 ALA A N   1 
ATOM   3530  C CA  . ALA A 1 440 ? -2.591  -51.857 -44.319 1.00 50.11  ? 440 ALA A CA  1 
ATOM   3531  C C   . ALA A 1 440 ? -2.719  -51.901 -45.839 1.00 53.26  ? 440 ALA A C   1 
ATOM   3532  O O   . ALA A 1 440 ? -1.821  -51.424 -46.505 1.00 53.11  ? 440 ALA A O   1 
ATOM   3533  C CB  . ALA A 1 440 ? -2.693  -50.426 -43.831 1.00 48.51  ? 440 ALA A CB  1 
ATOM   3534  N N   . GLY A 1 441 ? -3.825  -52.450 -46.371 1.00 57.78  ? 441 GLY A N   1 
ATOM   3535  C CA  . GLY A 1 441 ? -4.061  -52.493 -47.813 1.00 62.49  ? 441 GLY A CA  1 
ATOM   3536  C C   . GLY A 1 441 ? -3.222  -53.549 -48.553 1.00 67.80  ? 441 GLY A C   1 
ATOM   3537  O O   . GLY A 1 441 ? -2.901  -53.378 -49.734 1.00 68.71  ? 441 GLY A O   1 
ATOM   3538  N N   . SER A 1 442 ? -2.880  -54.644 -47.854 1.00 62.02  ? 442 SER A N   1 
ATOM   3539  C CA  . SER A 1 442 ? -2.085  -55.726 -48.415 1.00 60.71  ? 442 SER A CA  1 
ATOM   3540  C C   . SER A 1 442 ? -2.984  -56.929 -48.703 1.00 62.25  ? 442 SER A C   1 
ATOM   3541  O O   . SER A 1 442 ? -4.161  -56.925 -48.331 1.00 56.34  ? 442 SER A O   1 
ATOM   3542  C CB  . SER A 1 442 ? -0.945  -56.105 -47.496 1.00 53.33  ? 442 SER A CB  1 
ATOM   3543  O OG  . SER A 1 442 ? -1.421  -56.774 -46.337 1.00 47.12  ? 442 SER A OG  1 
ATOM   3544  N N   . LYS A 1 443 ? -2.395  -57.945 -49.357 1.00 64.49  ? 443 LYS A N   1 
ATOM   3545  C CA  . LYS A 1 443 ? -3.035  -59.225 -49.621 1.00 66.87  ? 443 LYS A CA  1 
ATOM   3546  C C   . LYS A 1 443 ? -3.374  -59.954 -48.311 1.00 60.47  ? 443 LYS A C   1 
ATOM   3547  O O   . LYS A 1 443 ? -4.490  -60.469 -48.169 1.00 57.89  ? 443 LYS A O   1 
ATOM   3548  C CB  . LYS A 1 443 ? -2.146  -60.051 -50.535 1.00 67.16  ? 443 LYS A CB  1 
ATOM   3549  N N   . LEU A 1 444 ? -2.421  -59.988 -47.357 1.00 56.81  ? 444 LEU A N   1 
ATOM   3550  C CA  . LEU A 1 444 ? -2.624  -60.630 -46.056 1.00 58.04  ? 444 LEU A CA  1 
ATOM   3551  C C   . LEU A 1 444 ? -3.737  -59.924 -45.274 1.00 57.03  ? 444 LEU A C   1 
ATOM   3552  O O   . LEU A 1 444 ? -4.525  -60.591 -44.614 1.00 56.43  ? 444 LEU A O   1 
ATOM   3553  C CB  . LEU A 1 444 ? -1.344  -60.704 -45.242 1.00 50.43  ? 444 LEU A CB  1 
ATOM   3554  N N   . ALA A 1 445 ? -3.823  -58.586 -45.376 1.00 54.42  ? 445 ALA A N   1 
ATOM   3555  C CA  . ALA A 1 445 ? -4.914  -57.841 -44.757 1.00 57.67  ? 445 ALA A CA  1 
ATOM   3556  C C   . ALA A 1 445 ? -6.257  -58.294 -45.336 1.00 63.40  ? 445 ALA A C   1 
ATOM   3557  O O   . ALA A 1 445 ? -7.205  -58.522 -44.577 1.00 55.27  ? 445 ALA A O   1 
ATOM   3558  C CB  . ALA A 1 445 ? -4.722  -56.346 -44.930 1.00 53.73  ? 445 ALA A CB  1 
ATOM   3559  N N   . ALA A 1 446 ? -6.327  -58.399 -46.678 1.00 59.29  ? 446 ALA A N   1 
ATOM   3560  C CA  . ALA A 1 446 ? -7.514  -58.874 -47.379 1.00 66.22  ? 446 ALA A CA  1 
ATOM   3561  C C   . ALA A 1 446 ? -7.941  -60.263 -46.872 1.00 66.40  ? 446 ALA A C   1 
ATOM   3562  O O   . ALA A 1 446 ? -9.114  -60.453 -46.531 1.00 57.17  ? 446 ALA A O   1 
ATOM   3563  C CB  . ALA A 1 446 ? -7.275  -58.862 -48.881 1.00 62.94  ? 446 ALA A CB  1 
ATOM   3564  N N   . ALA A 1 447 ? -6.990  -61.213 -46.776 1.00 65.66  ? 447 ALA A N   1 
ATOM   3565  C CA  . ALA A 1 447 ? -7.264  -62.566 -46.286 1.00 67.88  ? 447 ALA A CA  1 
ATOM   3566  C C   . ALA A 1 447 ? -7.804  -62.555 -44.848 1.00 72.60  ? 447 ALA A C   1 
ATOM   3567  O O   . ALA A 1 447 ? -8.751  -63.279 -44.539 1.00 68.04  ? 447 ALA A O   1 
ATOM   3568  C CB  . ALA A 1 447 ? -6.014  -63.421 -46.387 1.00 65.15  ? 447 ALA A CB  1 
ATOM   3569  N N   . LEU A 1 448 ? -7.214  -61.724 -43.974 1.00 67.61  ? 448 LEU A N   1 
ATOM   3570  C CA  . LEU A 1 448 ? -7.588  -61.673 -42.567 1.00 73.26  ? 448 LEU A CA  1 
ATOM   3571  C C   . LEU A 1 448 ? -8.982  -61.046 -42.378 1.00 64.58  ? 448 LEU A C   1 
ATOM   3572  O O   . LEU A 1 448 ? -9.360  -60.162 -43.194 1.00 64.82  ? 448 LEU A O   1 
ATOM   3573  C CB  . LEU A 1 448 ? -6.526  -60.925 -41.794 1.00 70.76  ? 448 LEU A CB  1 
ATOM   3574  N N   . MET B 1 1   ? 19.143  -37.233 -7.685  1.00 62.55  ? 1   MET B N   1 
ATOM   3575  C CA  . MET B 1 1   ? 18.048  -38.167 -7.325  1.00 57.55  ? 1   MET B CA  1 
ATOM   3576  C C   . MET B 1 1   ? 18.139  -39.373 -8.268  1.00 51.22  ? 1   MET B C   1 
ATOM   3577  O O   . MET B 1 1   ? 18.400  -39.198 -9.457  1.00 44.61  ? 1   MET B O   1 
ATOM   3578  C CB  . MET B 1 1   ? 16.714  -37.420 -7.448  1.00 62.15  ? 1   MET B CB  1 
ATOM   3579  C CG  . MET B 1 1   ? 15.484  -38.279 -7.332  1.00 67.77  ? 1   MET B CG  1 
ATOM   3580  S SD  . MET B 1 1   ? 13.995  -37.305 -7.698  1.00 65.15  ? 1   MET B SD  1 
ATOM   3581  C CE  . MET B 1 1   ? 12.819  -38.257 -6.735  1.00 64.82  ? 1   MET B CE  1 
ATOM   3582  N N   . LYS B 1 2   ? 17.933  -40.581 -7.724  1.00 53.04  ? 2   LYS B N   1 
ATOM   3583  C CA  . LYS B 1 2   ? 18.116  -41.822 -8.465  1.00 62.87  ? 2   LYS B CA  1 
ATOM   3584  C C   . LYS B 1 2   ? 17.151  -41.889 -9.649  1.00 53.96  ? 2   LYS B C   1 
ATOM   3585  O O   . LYS B 1 2   ? 17.577  -42.131 -10.780 1.00 46.28  ? 2   LYS B O   1 
ATOM   3586  C CB  . LYS B 1 2   ? 17.902  -43.024 -7.543  1.00 76.60  ? 2   LYS B CB  1 
ATOM   3587  C CG  . LYS B 1 2   ? 19.047  -43.315 -6.578  1.00 96.29  ? 2   LYS B CG  1 
ATOM   3588  C CD  . LYS B 1 2   ? 20.220  -44.072 -7.198  1.00 101.83 ? 2   LYS B CD  1 
ATOM   3589  C CE  . LYS B 1 2   ? 21.227  -44.544 -6.167  1.00 98.72  ? 2   LYS B CE  1 
ATOM   3590  N NZ  . LYS B 1 2   ? 22.340  -45.303 -6.784  1.00 98.68  ? 2   LYS B NZ  1 
ATOM   3591  N N   . LEU B 1 3   ? 15.858  -41.655 -9.373  1.00 47.97  ? 3   LEU B N   1 
ATOM   3592  C CA  . LEU B 1 3   ? 14.830  -41.661 -10.404 1.00 44.18  ? 3   LEU B CA  1 
ATOM   3593  C C   . LEU B 1 3   ? 15.345  -40.920 -11.631 1.00 41.30  ? 3   LEU B C   1 
ATOM   3594  O O   . LEU B 1 3   ? 15.235  -41.422 -12.741 1.00 44.74  ? 3   LEU B O   1 
ATOM   3595  C CB  . LEU B 1 3   ? 13.543  -41.049 -9.835  1.00 44.43  ? 3   LEU B CB  1 
ATOM   3596  C CG  . LEU B 1 3   ? 12.331  -40.964 -10.770 1.00 46.02  ? 3   LEU B CG  1 
ATOM   3597  C CD1 . LEU B 1 3   ? 11.911  -42.323 -11.321 1.00 46.71  ? 3   LEU B CD1 1 
ATOM   3598  C CD2 . LEU B 1 3   ? 11.151  -40.334 -10.034 1.00 45.78  ? 3   LEU B CD2 1 
ATOM   3599  N N   . LYS B 1 4   ? 15.957  -39.750 -11.425 1.00 41.59  ? 4   LYS B N   1 
ATOM   3600  C CA  . LYS B 1 4   ? 16.290  -38.872 -12.531 1.00 42.01  ? 4   LYS B CA  1 
ATOM   3601  C C   . LYS B 1 4   ? 17.482  -39.444 -13.314 1.00 43.52  ? 4   LYS B C   1 
ATOM   3602  O O   . LYS B 1 4   ? 17.451  -39.417 -14.545 1.00 44.60  ? 4   LYS B O   1 
ATOM   3603  C CB  . LYS B 1 4   ? 16.503  -37.436 -12.047 1.00 40.90  ? 4   LYS B CB  1 
ATOM   3604  C CG  . LYS B 1 4   ? 16.733  -36.406 -13.147 1.00 50.07  ? 4   LYS B CG  1 
ATOM   3605  C CD  . LYS B 1 4   ? 16.984  -35.023 -12.584 1.00 56.81  ? 4   LYS B CD  1 
ATOM   3606  C CE  . LYS B 1 4   ? 17.681  -34.091 -13.546 1.00 58.67  ? 4   LYS B CE  1 
ATOM   3607  N NZ  . LYS B 1 4   ? 16.869  -33.840 -14.751 1.00 64.17  ? 4   LYS B NZ  1 
ATOM   3608  N N   . GLU B 1 5   ? 18.514  -39.972 -12.634 1.00 47.64  ? 5   GLU B N   1 
ATOM   3609  C CA  . GLU B 1 5   ? 19.686  -40.533 -13.316 1.00 50.25  ? 5   GLU B CA  1 
ATOM   3610  C C   . GLU B 1 5   ? 19.304  -41.732 -14.179 1.00 50.33  ? 5   GLU B C   1 
ATOM   3611  O O   . GLU B 1 5   ? 19.809  -41.911 -15.286 1.00 54.17  ? 5   GLU B O   1 
ATOM   3612  C CB  . GLU B 1 5   ? 20.720  -41.097 -12.344 1.00 59.79  ? 5   GLU B CB  1 
ATOM   3613  C CG  . GLU B 1 5   ? 21.296  -40.083 -11.374 1.00 69.43  ? 5   GLU B CG  1 
ATOM   3614  C CD  . GLU B 1 5   ? 21.829  -40.700 -10.086 1.00 74.37  ? 5   GLU B CD  1 
ATOM   3615  O OE1 . GLU B 1 5   ? 22.537  -39.994 -9.363  1.00 71.60  ? 5   GLU B OE1 1 
ATOM   3616  O OE2 . GLU B 1 5   ? 21.523  -41.881 -9.802  1.00 80.56  ? 5   GLU B OE2 1 
ATOM   3617  N N   . ARG B 1 6   ? 18.389  -42.542 -13.642 1.00 42.20  ? 6   ARG B N   1 
ATOM   3618  C CA  . ARG B 1 6   ? 17.908  -43.726 -14.312 1.00 43.53  ? 6   ARG B CA  1 
ATOM   3619  C C   . ARG B 1 6   ? 17.136  -43.356 -15.587 1.00 44.48  ? 6   ARG B C   1 
ATOM   3620  O O   . ARG B 1 6   ? 17.371  -43.915 -16.661 1.00 40.62  ? 6   ARG B O   1 
ATOM   3621  C CB  . ARG B 1 6   ? 17.072  -44.481 -13.276 1.00 48.27  ? 6   ARG B CB  1 
ATOM   3622  C CG  . ARG B 1 6   ? 16.882  -45.942 -13.606 1.00 60.05  ? 6   ARG B CG  1 
ATOM   3623  C CD  . ARG B 1 6   ? 18.186  -46.704 -13.466 1.00 63.53  ? 6   ARG B CD  1 
ATOM   3624  N NE  . ARG B 1 6   ? 18.069  -47.851 -14.342 1.00 63.63  ? 6   ARG B NE  1 
ATOM   3625  C CZ  . ARG B 1 6   ? 18.690  -47.992 -15.502 1.00 60.95  ? 6   ARG B CZ  1 
ATOM   3626  N NH1 . ARG B 1 6   ? 19.704  -47.213 -15.822 1.00 68.14  ? 6   ARG B NH1 1 
ATOM   3627  N NH2 . ARG B 1 6   ? 18.315  -48.952 -16.324 1.00 61.64  ? 6   ARG B NH2 1 
ATOM   3628  N N   . LEU B 1 7   ? 16.204  -42.402 -15.466 1.00 37.81  ? 7   LEU B N   1 
ATOM   3629  C CA  . LEU B 1 7   ? 15.444  -41.915 -16.603 1.00 38.11  ? 7   LEU B CA  1 
ATOM   3630  C C   . LEU B 1 7   ? 16.385  -41.310 -17.649 1.00 37.27  ? 7   LEU B C   1 
ATOM   3631  O O   . LEU B 1 7   ? 16.104  -41.372 -18.854 1.00 37.76  ? 7   LEU B O   1 
ATOM   3632  C CB  . LEU B 1 7   ? 14.418  -40.880 -16.111 1.00 37.62  ? 7   LEU B CB  1 
ATOM   3633  C CG  . LEU B 1 7   ? 13.226  -41.456 -15.339 1.00 35.53  ? 7   LEU B CG  1 
ATOM   3634  C CD1 . LEU B 1 7   ? 12.248  -40.351 -14.932 1.00 37.61  ? 7   LEU B CD1 1 
ATOM   3635  C CD2 . LEU B 1 7   ? 12.501  -42.490 -16.175 1.00 37.35  ? 7   LEU B CD2 1 
ATOM   3636  N N   . ALA B 1 8   ? 17.465  -40.662 -17.192 1.00 34.95  ? 8   ALA B N   1 
ATOM   3637  C CA  . ALA B 1 8   ? 18.412  -40.042 -18.113 1.00 40.45  ? 8   ALA B CA  1 
ATOM   3638  C C   . ALA B 1 8   ? 19.071  -41.106 -19.004 1.00 40.60  ? 8   ALA B C   1 
ATOM   3639  O O   . ALA B 1 8   ? 19.517  -40.776 -20.109 1.00 37.80  ? 8   ALA B O   1 
ATOM   3640  C CB  . ALA B 1 8   ? 19.443  -39.247 -17.342 1.00 45.15  ? 8   ALA B CB  1 
ATOM   3641  N N   . GLU B 1 9   ? 19.080  -42.371 -18.540 1.00 42.06  ? 9   GLU B N   1 
ATOM   3642  C CA  . GLU B 1 9   ? 19.623  -43.492 -19.309 1.00 49.74  ? 9   GLU B CA  1 
ATOM   3643  C C   . GLU B 1 9   ? 18.527  -44.184 -20.118 1.00 45.32  ? 9   GLU B C   1 
ATOM   3644  O O   . GLU B 1 9   ? 18.744  -44.467 -21.283 1.00 46.88  ? 9   GLU B O   1 
ATOM   3645  C CB  . GLU B 1 9   ? 20.294  -44.540 -18.412 1.00 56.52  ? 9   GLU B CB  1 
ATOM   3646  C CG  . GLU B 1 9   ? 21.458  -43.996 -17.590 1.00 62.87  ? 9   GLU B CG  1 
ATOM   3647  C CD  . GLU B 1 9   ? 22.007  -44.917 -16.502 1.00 81.93  ? 9   GLU B CD  1 
ATOM   3648  O OE1 . GLU B 1 9   ? 23.257  -45.097 -16.450 1.00 85.60  ? 9   GLU B OE1 1 
ATOM   3649  O OE2 . GLU B 1 9   ? 21.196  -45.458 -15.695 1.00 68.98  ? 9   GLU B OE2 1 
ATOM   3650  N N   . LEU B 1 10  ? 17.368  -44.479 -19.507 1.00 40.82  ? 10  LEU B N   1 
ATOM   3651  C CA  . LEU B 1 10  ? 16.296  -45.190 -20.200 1.00 45.16  ? 10  LEU B CA  1 
ATOM   3652  C C   . LEU B 1 10  ? 15.607  -44.361 -21.287 1.00 47.71  ? 10  LEU B C   1 
ATOM   3653  O O   . LEU B 1 10  ? 15.230  -44.905 -22.322 1.00 48.30  ? 10  LEU B O   1 
ATOM   3654  C CB  . LEU B 1 10  ? 15.254  -45.628 -19.185 1.00 39.26  ? 10  LEU B CB  1 
ATOM   3655  C CG  . LEU B 1 10  ? 15.749  -46.672 -18.201 1.00 42.14  ? 10  LEU B CG  1 
ATOM   3656  C CD1 . LEU B 1 10  ? 14.795  -46.792 -17.009 1.00 41.79  ? 10  LEU B CD1 1 
ATOM   3657  C CD2 . LEU B 1 10  ? 15.902  -48.012 -18.916 1.00 46.27  ? 10  LEU B CD2 1 
ATOM   3658  N N   . ILE B 1 11  ? 15.383  -43.065 -21.061 1.00 42.60  ? 11  ILE B N   1 
ATOM   3659  C CA  . ILE B 1 11  ? 14.541  -42.324 -21.986 1.00 43.64  ? 11  ILE B CA  1 
ATOM   3660  C C   . ILE B 1 11  ? 15.207  -42.207 -23.357 1.00 40.45  ? 11  ILE B C   1 
ATOM   3661  O O   . ILE B 1 11  ? 14.521  -42.302 -24.374 1.00 39.54  ? 11  ILE B O   1 
ATOM   3662  C CB  . ILE B 1 11  ? 14.093  -40.966 -21.391 1.00 45.22  ? 11  ILE B CB  1 
ATOM   3663  C CG1 . ILE B 1 11  ? 12.991  -41.184 -20.347 1.00 40.00  ? 11  ILE B CG1 1 
ATOM   3664  C CG2 . ILE B 1 11  ? 13.657  -39.986 -22.480 1.00 46.47  ? 11  ILE B CG2 1 
ATOM   3665  C CD1 . ILE B 1 11  ? 12.498  -39.916 -19.682 1.00 45.83  ? 11  ILE B CD1 1 
ATOM   3666  N N   . PRO B 1 12  ? 16.523  -41.927 -23.476 1.00 41.98  ? 12  PRO B N   1 
ATOM   3667  C CA  . PRO B 1 12  ? 17.154  -41.874 -24.799 1.00 42.80  ? 12  PRO B CA  1 
ATOM   3668  C C   . PRO B 1 12  ? 16.981  -43.177 -25.577 1.00 43.44  ? 12  PRO B C   1 
ATOM   3669  O O   . PRO B 1 12  ? 16.815  -43.144 -26.801 1.00 37.54  ? 12  PRO B O   1 
ATOM   3670  C CB  . PRO B 1 12  ? 18.630  -41.556 -24.494 1.00 48.86  ? 12  PRO B CB  1 
ATOM   3671  C CG  . PRO B 1 12  ? 18.573  -40.840 -23.148 1.00 47.08  ? 12  PRO B CG  1 
ATOM   3672  C CD  . PRO B 1 12  ? 17.428  -41.505 -22.397 1.00 43.82  ? 12  PRO B CD  1 
ATOM   3673  N N   . GLN B 1 13  ? 16.979  -44.313 -24.854 1.00 42.88  ? 13  GLN B N   1 
ATOM   3674  C CA  . GLN B 1 13  ? 16.800  -45.618 -25.478 1.00 47.76  ? 13  GLN B CA  1 
ATOM   3675  C C   . GLN B 1 13  ? 15.363  -45.770 -25.956 1.00 45.37  ? 13  GLN B C   1 
ATOM   3676  O O   . GLN B 1 13  ? 15.132  -46.225 -27.068 1.00 41.35  ? 13  GLN B O   1 
ATOM   3677  C CB  . GLN B 1 13  ? 17.122  -46.774 -24.527 1.00 51.33  ? 13  GLN B CB  1 
ATOM   3678  C CG  . GLN B 1 13  ? 18.561  -46.779 -24.023 1.00 56.78  ? 13  GLN B CG  1 
ATOM   3679  C CD  . GLN B 1 13  ? 18.714  -47.706 -22.839 1.00 60.03  ? 13  GLN B CD  1 
ATOM   3680  O OE1 . GLN B 1 13  ? 17.987  -48.683 -22.685 1.00 67.81  ? 13  GLN B OE1 1 
ATOM   3681  N NE2 . GLN B 1 13  ? 19.657  -47.399 -21.970 1.00 63.87  ? 13  GLN B NE2 1 
ATOM   3682  N N   . TRP B 1 14  ? 14.395  -45.416 -25.104 1.00 40.91  ? 14  TRP B N   1 
ATOM   3683  C CA  . TRP B 1 14  ? 12.993  -45.526 -25.480 1.00 41.34  ? 14  TRP B CA  1 
ATOM   3684  C C   . TRP B 1 14  ? 12.680  -44.636 -26.679 1.00 38.51  ? 14  TRP B C   1 
ATOM   3685  O O   . TRP B 1 14  ? 11.983  -45.053 -27.587 1.00 38.59  ? 14  TRP B O   1 
ATOM   3686  C CB  . TRP B 1 14  ? 12.095  -45.191 -24.298 1.00 42.59  ? 14  TRP B CB  1 
ATOM   3687  C CG  . TRP B 1 14  ? 12.164  -46.184 -23.188 1.00 44.63  ? 14  TRP B CG  1 
ATOM   3688  C CD1 . TRP B 1 14  ? 12.549  -47.486 -23.263 1.00 52.02  ? 14  TRP B CD1 1 
ATOM   3689  C CD2 . TRP B 1 14  ? 11.871  -45.931 -21.805 1.00 48.43  ? 14  TRP B CD2 1 
ATOM   3690  N NE1 . TRP B 1 14  ? 12.454  -48.082 -22.034 1.00 50.10  ? 14  TRP B NE1 1 
ATOM   3691  C CE2 . TRP B 1 14  ? 12.052  -47.153 -21.116 1.00 49.10  ? 14  TRP B CE2 1 
ATOM   3692  C CE3 . TRP B 1 14  ? 11.441  -44.806 -21.096 1.00 40.24  ? 14  TRP B CE3 1 
ATOM   3693  C CZ2 . TRP B 1 14  ? 11.828  -47.282 -19.750 1.00 43.52  ? 14  TRP B CZ2 1 
ATOM   3694  C CZ3 . TRP B 1 14  ? 11.196  -44.940 -19.744 1.00 41.28  ? 14  TRP B CZ3 1 
ATOM   3695  C CH2 . TRP B 1 14  ? 11.407  -46.151 -19.081 1.00 44.85  ? 14  TRP B CH2 1 
ATOM   3696  N N   . ARG B 1 15  ? 13.170  -43.397 -26.657 1.00 34.80  ? 15  ARG B N   1 
ATOM   3697  C CA  . ARG B 1 15  ? 12.962  -42.471 -27.743 1.00 38.85  ? 15  ARG B CA  1 
ATOM   3698  C C   . ARG B 1 15  ? 13.407  -43.131 -29.065 1.00 38.92  ? 15  ARG B C   1 
ATOM   3699  O O   . ARG B 1 15  ? 12.683  -43.108 -30.055 1.00 35.18  ? 15  ARG B O   1 
ATOM   3700  C CB  . ARG B 1 15  ? 13.736  -41.196 -27.391 1.00 41.03  ? 15  ARG B CB  1 
ATOM   3701  C CG  . ARG B 1 15  ? 13.682  -40.114 -28.449 1.00 47.25  ? 15  ARG B CG  1 
ATOM   3702  C CD  . ARG B 1 15  ? 14.731  -39.038 -28.242 1.00 50.95  ? 15  ARG B CD  1 
ATOM   3703  N NE  . ARG B 1 15  ? 14.678  -38.197 -29.435 1.00 60.56  ? 15  ARG B NE  1 
ATOM   3704  C CZ  . ARG B 1 15  ? 15.592  -37.301 -29.810 1.00 71.39  ? 15  ARG B CZ  1 
ATOM   3705  N NH1 . ARG B 1 15  ? 16.742  -37.193 -29.171 1.00 71.98  ? 15  ARG B NH1 1 
ATOM   3706  N NH2 . ARG B 1 15  ? 15.358  -36.524 -30.856 1.00 77.71  ? 15  ARG B NH2 1 
ATOM   3707  N N   . ALA B 1 16  ? 14.602  -43.721 -29.075 1.00 38.95  ? 16  ALA B N   1 
ATOM   3708  C CA  . ALA B 1 16  ? 15.139  -44.332 -30.289 1.00 41.33  ? 16  ALA B CA  1 
ATOM   3709  C C   . ALA B 1 16  ? 14.282  -45.531 -30.695 1.00 37.47  ? 16  ALA B C   1 
ATOM   3710  O O   . ALA B 1 16  ? 13.919  -45.672 -31.860 1.00 40.55  ? 16  ALA B O   1 
ATOM   3711  C CB  . ALA B 1 16  ? 16.607  -44.683 -30.136 1.00 37.56  ? 16  ALA B CB  1 
ATOM   3712  N N   . GLU B 1 17  ? 13.912  -46.372 -29.731 1.00 36.01  ? 17  GLU B N   1 
ATOM   3713  C CA  . GLU B 1 17  ? 13.089  -47.528 -30.033 1.00 38.97  ? 17  GLU B CA  1 
ATOM   3714  C C   . GLU B 1 17  ? 11.773  -47.109 -30.687 1.00 41.17  ? 17  GLU B C   1 
ATOM   3715  O O   . GLU B 1 17  ? 11.319  -47.710 -31.667 1.00 36.89  ? 17  GLU B O   1 
ATOM   3716  C CB  . GLU B 1 17  ? 12.836  -48.340 -28.761 1.00 41.84  ? 17  GLU B CB  1 
ATOM   3717  C CG  . GLU B 1 17  ? 11.851  -49.486 -28.937 1.00 49.87  ? 17  GLU B CG  1 
ATOM   3718  C CD  . GLU B 1 17  ? 12.319  -50.602 -29.863 1.00 71.16  ? 17  GLU B CD  1 
ATOM   3719  O OE1 . GLU B 1 17  ? 13.530  -50.631 -30.175 1.00 77.51  ? 17  GLU B OE1 1 
ATOM   3720  O OE2 . GLU B 1 17  ? 11.476  -51.439 -30.294 1.00 70.99  ? 17  GLU B OE2 1 
ATOM   3721  N N   . VAL B 1 18  ? 11.121  -46.091 -30.114 1.00 37.89  ? 18  VAL B N   1 
ATOM   3722  C CA  . VAL B 1 18  ? 9.846   -45.632 -30.637 1.00 36.37  ? 18  VAL B CA  1 
ATOM   3723  C C   . VAL B 1 18  ? 10.010  -45.059 -32.044 1.00 33.04  ? 18  VAL B C   1 
ATOM   3724  O O   . VAL B 1 18  ? 9.145   -45.285 -32.882 1.00 37.92  ? 18  VAL B O   1 
ATOM   3725  C CB  . VAL B 1 18  ? 9.185   -44.630 -29.672 1.00 34.42  ? 18  VAL B CB  1 
ATOM   3726  C CG1 . VAL B 1 18  ? 8.103   -43.816 -30.338 1.00 37.91  ? 18  VAL B CG1 1 
ATOM   3727  C CG2 . VAL B 1 18  ? 8.696   -45.333 -28.418 1.00 36.09  ? 18  VAL B CG2 1 
ATOM   3728  N N   . ALA B 1 19  ? 11.062  -44.282 -32.316 1.00 38.83  ? 19  ALA B N   1 
ATOM   3729  C CA  . ALA B 1 19  ? 11.276  -43.795 -33.673 1.00 37.90  ? 19  ALA B CA  1 
ATOM   3730  C C   . ALA B 1 19  ? 11.381  -44.991 -34.646 1.00 36.15  ? 19  ALA B C   1 
ATOM   3731  O O   . ALA B 1 19  ? 10.781  -44.975 -35.718 1.00 34.53  ? 19  ALA B O   1 
ATOM   3732  C CB  . ALA B 1 19  ? 12.490  -42.890 -33.742 1.00 38.09  ? 19  ALA B CB  1 
ATOM   3733  N N   . GLU B 1 20  ? 12.083  -46.053 -34.249 1.00 38.94  ? 20  GLU B N   1 
ATOM   3734  C CA  . GLU B 1 20  ? 12.267  -47.233 -35.099 1.00 39.05  ? 20  GLU B CA  1 
ATOM   3735  C C   . GLU B 1 20  ? 10.944  -47.949 -35.347 1.00 40.11  ? 20  GLU B C   1 
ATOM   3736  O O   . GLU B 1 20  ? 10.663  -48.289 -36.496 1.00 39.40  ? 20  GLU B O   1 
ATOM   3737  C CB  . GLU B 1 20  ? 13.229  -48.232 -34.472 1.00 38.73  ? 20  GLU B CB  1 
ATOM   3738  C CG  . GLU B 1 20  ? 14.641  -47.681 -34.381 1.00 48.20  ? 20  GLU B CG  1 
ATOM   3739  C CD  . GLU B 1 20  ? 15.712  -48.729 -34.134 1.00 53.26  ? 20  GLU B CD  1 
ATOM   3740  O OE1 . GLU B 1 20  ? 15.350  -49.865 -33.755 1.00 60.26  ? 20  GLU B OE1 1 
ATOM   3741  O OE2 . GLU B 1 20  ? 16.894  -48.428 -34.379 1.00 65.58  ? 20  GLU B OE2 1 
ATOM   3742  N N   . ILE B 1 21  ? 10.134  -48.126 -34.290 1.00 36.33  ? 21  ILE B N   1 
ATOM   3743  C CA  . ILE B 1 21  ? 8.812   -48.730 -34.394 1.00 41.54  ? 21  ILE B CA  1 
ATOM   3744  C C   . ILE B 1 21  ? 7.897   -47.978 -35.360 1.00 40.39  ? 21  ILE B C   1 
ATOM   3745  O O   . ILE B 1 21  ? 7.187   -48.577 -36.168 1.00 36.93  ? 21  ILE B O   1 
ATOM   3746  C CB  . ILE B 1 21  ? 8.164   -48.840 -33.002 1.00 40.57  ? 21  ILE B CB  1 
ATOM   3747  C CG1 . ILE B 1 21  ? 8.765   -50.007 -32.220 1.00 44.86  ? 21  ILE B CG1 1 
ATOM   3748  C CG2 . ILE B 1 21  ? 6.663   -48.949 -33.113 1.00 40.93  ? 21  ILE B CG2 1 
ATOM   3749  C CD1 . ILE B 1 21  ? 8.461   -49.980 -30.736 1.00 47.59  ? 21  ILE B CD1 1 
ATOM   3750  N N   . ARG B 1 22  ? 7.851   -46.660 -35.233 1.00 34.98  ? 22  ARG B N   1 
ATOM   3751  C CA  . ARG B 1 22  ? 7.008   -45.848 -36.089 1.00 37.91  ? 22  ARG B CA  1 
ATOM   3752  C C   . ARG B 1 22  ? 7.461   -46.026 -37.544 1.00 39.24  ? 22  ARG B C   1 
ATOM   3753  O O   . ARG B 1 22  ? 6.670   -45.974 -38.473 1.00 41.30  ? 22  ARG B O   1 
ATOM   3754  C CB  . ARG B 1 22  ? 7.101   -44.373 -35.652 1.00 37.53  ? 22  ARG B CB  1 
ATOM   3755  C CG  . ARG B 1 22  ? 6.522   -44.071 -34.271 1.00 40.27  ? 22  ARG B CG  1 
ATOM   3756  C CD  . ARG B 1 22  ? 6.495   -42.583 -33.887 1.00 38.96  ? 22  ARG B CD  1 
ATOM   3757  N NE  . ARG B 1 22  ? 5.659   -41.790 -34.784 1.00 43.56  ? 22  ARG B NE  1 
ATOM   3758  C CZ  . ARG B 1 22  ? 5.774   -40.479 -34.976 1.00 41.35  ? 22  ARG B CZ  1 
ATOM   3759  N NH1 . ARG B 1 22  ? 6.696   -39.808 -34.314 1.00 43.74  ? 22  ARG B NH1 1 
ATOM   3760  N NH2 . ARG B 1 22  ? 4.982   -39.840 -35.823 1.00 41.29  ? 22  ARG B NH2 1 
ATOM   3761  N N   . LYS B 1 23  ? 8.766   -46.195 -37.730 1.00 36.86  ? 23  LYS B N   1 
ATOM   3762  C CA  . LYS B 1 23  ? 9.326   -46.383 -39.056 1.00 44.63  ? 23  LYS B CA  1 
ATOM   3763  C C   . LYS B 1 23  ? 8.936   -47.758 -39.597 1.00 40.05  ? 23  LYS B C   1 
ATOM   3764  O O   . LYS B 1 23  ? 8.328   -47.856 -40.659 1.00 37.15  ? 23  LYS B O   1 
ATOM   3765  C CB  . LYS B 1 23  ? 10.846  -46.194 -39.005 1.00 50.10  ? 23  LYS B CB  1 
ATOM   3766  C CG  . LYS B 1 23  ? 11.448  -45.641 -40.280 1.00 62.85  ? 23  LYS B CG  1 
ATOM   3767  C CD  . LYS B 1 23  ? 11.049  -44.221 -40.557 1.00 73.95  ? 23  LYS B CD  1 
ATOM   3768  C CE  . LYS B 1 23  ? 10.947  -43.944 -42.038 1.00 76.24  ? 23  LYS B CE  1 
ATOM   3769  N NZ  . LYS B 1 23  ? 10.665  -42.515 -42.291 1.00 83.96  ? 23  LYS B NZ  1 
ATOM   3770  N N   . LYS B 1 24  ? 9.230   -48.828 -38.854 1.00 39.47  ? 24  LYS B N   1 
ATOM   3771  C CA  . LYS B 1 24  ? 9.170   -50.161 -39.433 1.00 40.78  ? 24  LYS B CA  1 
ATOM   3772  C C   . LYS B 1 24  ? 7.821   -50.857 -39.207 1.00 42.33  ? 24  LYS B C   1 
ATOM   3773  O O   . LYS B 1 24  ? 7.523   -51.819 -39.907 1.00 38.36  ? 24  LYS B O   1 
ATOM   3774  C CB  . LYS B 1 24  ? 10.362  -50.976 -38.935 1.00 38.74  ? 24  LYS B CB  1 
ATOM   3775  C CG  . LYS B 1 24  ? 10.257  -51.509 -37.522 1.00 39.32  ? 24  LYS B CG  1 
ATOM   3776  C CD  . LYS B 1 24  ? 11.564  -52.162 -37.087 1.00 40.81  ? 24  LYS B CD  1 
ATOM   3777  C CE  . LYS B 1 24  ? 11.439  -52.942 -35.800 1.00 41.34  ? 24  LYS B CE  1 
ATOM   3778  N NZ  . LYS B 1 24  ? 12.768  -53.165 -35.205 1.00 42.76  ? 24  LYS B NZ  1 
ATOM   3779  N N   . TYR B 1 25  ? 6.953   -50.345 -38.315 1.00 37.82  ? 25  TYR B N   1 
ATOM   3780  C CA  . TYR B 1 25  ? 5.649   -50.958 -38.106 1.00 32.93  ? 25  TYR B CA  1 
ATOM   3781  C C   . TYR B 1 25  ? 4.491   -49.980 -38.282 1.00 32.33  ? 25  TYR B C   1 
ATOM   3782  O O   . TYR B 1 25  ? 3.343   -50.332 -38.041 1.00 35.52  ? 25  TYR B O   1 
ATOM   3783  C CB  . TYR B 1 25  ? 5.563   -51.567 -36.701 1.00 36.07  ? 25  TYR B CB  1 
ATOM   3784  C CG  . TYR B 1 25  ? 6.558   -52.646 -36.345 1.00 36.53  ? 25  TYR B CG  1 
ATOM   3785  C CD1 . TYR B 1 25  ? 6.955   -53.617 -37.264 1.00 41.72  ? 25  TYR B CD1 1 
ATOM   3786  C CD2 . TYR B 1 25  ? 7.030   -52.762 -35.049 1.00 37.26  ? 25  TYR B CD2 1 
ATOM   3787  C CE1 . TYR B 1 25  ? 7.835   -54.636 -36.917 1.00 40.13  ? 25  TYR B CE1 1 
ATOM   3788  C CE2 . TYR B 1 25  ? 7.933   -53.752 -34.690 1.00 39.71  ? 25  TYR B CE2 1 
ATOM   3789  C CZ  . TYR B 1 25  ? 8.315   -54.711 -35.621 1.00 44.89  ? 25  TYR B CZ  1 
ATOM   3790  O OH  . TYR B 1 25  ? 9.172   -55.713 -35.253 1.00 43.11  ? 25  TYR B OH  1 
ATOM   3791  N N   . GLY B 1 26  ? 4.788   -48.740 -38.635 1.00 34.92  ? 26  GLY B N   1 
ATOM   3792  C CA  . GLY B 1 26  ? 3.782   -47.699 -38.725 1.00 38.84  ? 26  GLY B CA  1 
ATOM   3793  C C   . GLY B 1 26  ? 2.600   -48.106 -39.592 1.00 41.76  ? 26  GLY B C   1 
ATOM   3794  O O   . GLY B 1 26  ? 1.473   -47.746 -39.285 1.00 32.66  ? 26  GLY B O   1 
ATOM   3795  N N   . ASN B 1 27  ? 2.865   -48.868 -40.666 1.00 39.52  ? 27  ASN B N   1 
ATOM   3796  C CA  . ASN B 1 27  ? 1.823   -49.220 -41.610 1.00 39.44  ? 27  ASN B CA  1 
ATOM   3797  C C   . ASN B 1 27  ? 1.103   -50.515 -41.219 1.00 38.07  ? 27  ASN B C   1 
ATOM   3798  O O   . ASN B 1 27  ? 0.286   -51.024 -41.977 1.00 39.69  ? 27  ASN B O   1 
ATOM   3799  C CB  . ASN B 1 27  ? 2.363   -49.213 -43.051 1.00 43.64  ? 27  ASN B CB  1 
ATOM   3800  C CG  . ASN B 1 27  ? 3.463   -50.216 -43.368 1.00 46.71  ? 27  ASN B CG  1 
ATOM   3801  O OD1 . ASN B 1 27  ? 3.879   -50.325 -44.524 1.00 54.41  ? 27  ASN B OD1 1 
ATOM   3802  N ND2 . ASN B 1 27  ? 3.931   -50.982 -42.398 1.00 42.11  ? 27  ASN B ND2 1 
ATOM   3803  N N   . ARG B 1 28  ? 1.325   -51.057 -40.025 1.00 36.04  ? 28  ARG B N   1 
ATOM   3804  C CA  . ARG B 1 28  ? 0.661   -52.308 -39.689 1.00 37.08  ? 28  ARG B CA  1 
ATOM   3805  C C   . ARG B 1 28  ? -0.765  -52.061 -39.206 1.00 42.36  ? 28  ARG B C   1 
ATOM   3806  O O   . ARG B 1 28  ? -1.004  -51.212 -38.338 1.00 39.04  ? 28  ARG B O   1 
ATOM   3807  C CB  . ARG B 1 28  ? 1.466   -53.068 -38.640 1.00 35.47  ? 28  ARG B CB  1 
ATOM   3808  C CG  . ARG B 1 28  ? 2.858   -53.478 -39.092 1.00 38.42  ? 28  ARG B CG  1 
ATOM   3809  C CD  . ARG B 1 28  ? 2.870   -54.725 -39.970 1.00 38.89  ? 28  ARG B CD  1 
ATOM   3810  N NE  . ARG B 1 28  ? 4.212   -55.031 -40.469 1.00 40.59  ? 28  ARG B NE  1 
ATOM   3811  C CZ  . ARG B 1 28  ? 4.718   -56.262 -40.556 1.00 41.00  ? 28  ARG B CZ  1 
ATOM   3812  N NH1 . ARG B 1 28  ? 6.003   -56.406 -40.785 1.00 39.26  ? 28  ARG B NH1 1 
ATOM   3813  N NH2 . ARG B 1 28  ? 3.957   -57.336 -40.373 1.00 40.88  ? 28  ARG B NH2 1 
ATOM   3814  N N   . LYS B 1 29  ? -1.706  -52.859 -39.728 1.00 37.82  ? 29  LYS B N   1 
ATOM   3815  C CA  . LYS B 1 29  ? -3.120  -52.683 -39.448 1.00 38.57  ? 29  LYS B CA  1 
ATOM   3816  C C   . LYS B 1 29  ? -3.466  -53.352 -38.122 1.00 37.42  ? 29  LYS B C   1 
ATOM   3817  O O   . LYS B 1 29  ? -3.098  -54.491 -37.895 1.00 38.37  ? 29  LYS B O   1 
ATOM   3818  C CB  . LYS B 1 29  ? -3.997  -53.238 -40.572 1.00 39.16  ? 29  LYS B CB  1 
ATOM   3819  C CG  . LYS B 1 29  ? -5.490  -53.268 -40.258 1.00 42.35  ? 29  LYS B CG  1 
ATOM   3820  C CD  . LYS B 1 29  ? -6.331  -54.058 -41.265 1.00 42.97  ? 29  LYS B CD  1 
ATOM   3821  C CE  . LYS B 1 29  ? -7.804  -53.985 -40.914 1.00 49.30  ? 29  LYS B CE  1 
ATOM   3822  N NZ  . LYS B 1 29  ? -8.651  -54.889 -41.732 1.00 48.17  ? 29  LYS B NZ  1 
ATOM   3823  N N   . THR B 1 30  ? -4.155  -52.626 -37.227 1.00 36.47  ? 30  THR B N   1 
ATOM   3824  C CA  . THR B 1 30  ? -4.577  -53.212 -35.960 1.00 35.96  ? 30  THR B CA  1 
ATOM   3825  C C   . THR B 1 30  ? -6.064  -53.508 -36.015 1.00 34.11  ? 30  THR B C   1 
ATOM   3826  O O   . THR B 1 30  ? -6.523  -54.392 -35.302 1.00 39.54  ? 30  THR B O   1 
ATOM   3827  C CB  . THR B 1 30  ? -4.275  -52.334 -34.726 1.00 37.98  ? 30  THR B CB  1 
ATOM   3828  O OG1 . THR B 1 30  ? -4.893  -51.070 -34.933 1.00 36.89  ? 30  THR B OG1 1 
ATOM   3829  C CG2 . THR B 1 30  ? -2.799  -52.150 -34.458 1.00 35.05  ? 30  THR B CG2 1 
ATOM   3830  N N   . MET B 1 31  ? -6.816  -52.765 -36.835 1.00 33.89  ? 31  MET B N   1 
ATOM   3831  C CA  . MET B 1 31  ? -8.252  -52.967 -36.882 1.00 36.28  ? 31  MET B CA  1 
ATOM   3832  C C   . MET B 1 31  ? -8.869  -52.039 -37.915 1.00 41.41  ? 31  MET B C   1 
ATOM   3833  O O   . MET B 1 31  ? -8.205  -51.157 -38.481 1.00 39.70  ? 31  MET B O   1 
ATOM   3834  C CB  . MET B 1 31  ? -8.906  -52.694 -35.523 1.00 40.92  ? 31  MET B CB  1 
ATOM   3835  C CG  . MET B 1 31  ? -8.588  -51.291 -34.981 1.00 39.58  ? 31  MET B CG  1 
ATOM   3836  S SD  . MET B 1 31  ? -9.164  -51.079 -33.255 1.00 39.10  ? 31  MET B SD  1 
ATOM   3837  C CE  . MET B 1 31  ? -10.937 -51.316 -33.393 1.00 39.20  ? 31  MET B CE  1 
ATOM   3838  N N   . ASP B 1 32  ? -10.166 -52.268 -38.137 1.00 38.42  ? 32  ASP B N   1 
ATOM   3839  C CA  . ASP B 1 32  ? -10.941 -51.414 -39.003 1.00 39.48  ? 32  ASP B CA  1 
ATOM   3840  C C   . ASP B 1 32  ? -11.481 -50.246 -38.177 1.00 39.89  ? 32  ASP B C   1 
ATOM   3841  O O   . ASP B 1 32  ? -11.932 -50.414 -37.052 1.00 41.41  ? 32  ASP B O   1 
ATOM   3842  C CB  . ASP B 1 32  ? -12.112 -52.189 -39.626 1.00 47.20  ? 32  ASP B CB  1 
ATOM   3843  C CG  . ASP B 1 32  ? -11.734 -53.306 -40.603 1.00 43.93  ? 32  ASP B CG  1 
ATOM   3844  O OD1 . ASP B 1 32  ? -10.672 -53.243 -41.211 1.00 45.72  ? 32  ASP B OD1 1 
ATOM   3845  O OD2 . ASP B 1 32  ? -12.530 -54.215 -40.749 1.00 41.31  ? 32  ASP B OD2 1 
ATOM   3846  N N   . CYS B 1 33  ? -11.518 -49.079 -38.804 1.00 44.72  ? 33  CYS B N   1 
ATOM   3847  C CA  . CYS B 1 33  ? -12.190 -47.913 -38.270 1.00 39.44  ? 33  CYS B CA  1 
ATOM   3848  C C   . CYS B 1 33  ? -13.533 -47.826 -38.988 1.00 39.20  ? 33  CYS B C   1 
ATOM   3849  O O   . CYS B 1 33  ? -13.605 -48.025 -40.200 1.00 39.99  ? 33  CYS B O   1 
ATOM   3850  C CB  . CYS B 1 33  ? -11.269 -46.706 -38.462 1.00 44.46  ? 33  CYS B CB  1 
ATOM   3851  S SG  . CYS B 1 33  ? -11.925 -45.136 -37.835 1.00 44.67  ? 33  CYS B SG  1 
ATOM   3852  N N   . THR B 1 34  ? -14.591 -47.552 -38.230 1.00 41.93  ? 34  THR B N   1 
ATOM   3853  C CA  . THR B 1 34  ? -15.957 -47.639 -38.704 1.00 40.68  ? 34  THR B CA  1 
ATOM   3854  C C   . THR B 1 34  ? -16.672 -46.311 -38.463 1.00 45.33  ? 34  THR B C   1 
ATOM   3855  O O   . THR B 1 34  ? -16.164 -45.431 -37.762 1.00 42.62  ? 34  THR B O   1 
ATOM   3856  C CB  . THR B 1 34  ? -16.713 -48.803 -38.049 1.00 41.84  ? 34  THR B CB  1 
ATOM   3857  O OG1 . THR B 1 34  ? -17.009 -48.498 -36.688 1.00 40.31  ? 34  THR B OG1 1 
ATOM   3858  C CG2 . THR B 1 34  ? -15.978 -50.130 -38.115 1.00 42.02  ? 34  THR B CG2 1 
ATOM   3859  N N   . ILE B 1 35  ? -17.839 -46.180 -39.092 1.00 40.08  ? 35  ILE B N   1 
ATOM   3860  C CA  . ILE B 1 35  ? -18.785 -45.098 -38.864 1.00 41.96  ? 35  ILE B CA  1 
ATOM   3861  C C   . ILE B 1 35  ? -19.183 -45.141 -37.391 1.00 43.34  ? 35  ILE B C   1 
ATOM   3862  O O   . ILE B 1 35  ? -19.344 -44.114 -36.730 1.00 43.13  ? 35  ILE B O   1 
ATOM   3863  C CB  . ILE B 1 35  ? -19.997 -45.225 -39.824 1.00 39.56  ? 35  ILE B CB  1 
ATOM   3864  C CG1 . ILE B 1 35  ? -19.616 -44.960 -41.282 1.00 41.31  ? 35  ILE B CG1 1 
ATOM   3865  C CG2 . ILE B 1 35  ? -21.139 -44.318 -39.438 1.00 41.24  ? 35  ILE B CG2 1 
ATOM   3866  C CD1 . ILE B 1 35  ? -19.327 -43.496 -41.580 1.00 43.70  ? 35  ILE B CD1 1 
ATOM   3867  N N   . GLY B 1 36  ? -19.322 -46.361 -36.894 1.00 37.30  ? 36  GLY B N   1 
ATOM   3868  C CA  . GLY B 1 36  ? -19.705 -46.621 -35.530 1.00 36.63  ? 36  GLY B CA  1 
ATOM   3869  C C   . GLY B 1 36  ? -18.714 -46.006 -34.534 1.00 39.67  ? 36  GLY B C   1 
ATOM   3870  O O   . GLY B 1 36  ? -19.148 -45.499 -33.502 1.00 40.47  ? 36  GLY B O   1 
ATOM   3871  N N   . HIS B 1 37  ? -17.410 -46.082 -34.826 1.00 38.46  ? 37  HIS B N   1 
ATOM   3872  C CA  . HIS B 1 37  ? -16.388 -45.467 -33.976 1.00 40.93  ? 37  HIS B CA  1 
ATOM   3873  C C   . HIS B 1 37  ? -16.592 -43.946 -33.908 1.00 43.85  ? 37  HIS B C   1 
ATOM   3874  O O   . HIS B 1 37  ? -16.566 -43.357 -32.824 1.00 39.14  ? 37  HIS B O   1 
ATOM   3875  C CB  . HIS B 1 37  ? -14.984 -45.829 -34.452 1.00 39.92  ? 37  HIS B CB  1 
ATOM   3876  C CG  . HIS B 1 37  ? -14.622 -47.272 -34.298 1.00 45.31  ? 37  HIS B CG  1 
ATOM   3877  N ND1 . HIS B 1 37  ? -14.489 -47.898 -33.074 1.00 47.03  ? 37  HIS B ND1 1 
ATOM   3878  C CD2 . HIS B 1 37  ? -14.320 -48.202 -35.208 1.00 44.41  ? 37  HIS B CD2 1 
ATOM   3879  C CE1 . HIS B 1 37  ? -14.139 -49.165 -33.258 1.00 41.32  ? 37  HIS B CE1 1 
ATOM   3880  N NE2 . HIS B 1 37  ? -14.036 -49.371 -34.543 1.00 46.95  ? 37  HIS B NE2 1 
ATOM   3881  N N   . ALA B 1 38  ? -16.878 -43.326 -35.060 1.00 35.69  ? 38  ALA B N   1 
ATOM   3882  C CA  . ALA B 1 38  ? -16.960 -41.880 -35.143 1.00 39.81  ? 38  ALA B CA  1 
ATOM   3883  C C   . ALA B 1 38  ? -18.156 -41.352 -34.353 1.00 42.47  ? 38  ALA B C   1 
ATOM   3884  O O   . ALA B 1 38  ? -18.027 -40.317 -33.696 1.00 42.55  ? 38  ALA B O   1 
ATOM   3885  C CB  . ALA B 1 38  ? -16.964 -41.420 -36.579 1.00 41.69  ? 38  ALA B CB  1 
ATOM   3886  N N   . TYR B 1 39  ? -19.277 -42.085 -34.356 1.00 35.30  ? 39  TYR B N   1 
ATOM   3887  C CA  . TYR B 1 39  ? -20.484 -41.643 -33.693 1.00 35.47  ? 39  TYR B CA  1 
ATOM   3888  C C   . TYR B 1 39  ? -20.614 -42.301 -32.325 1.00 36.53  ? 39  TYR B C   1 
ATOM   3889  O O   . TYR B 1 39  ? -21.564 -42.008 -31.607 1.00 37.58  ? 39  TYR B O   1 
ATOM   3890  C CB  . TYR B 1 39  ? -21.743 -41.999 -34.499 1.00 35.26  ? 39  TYR B CB  1 
ATOM   3891  C CG  . TYR B 1 39  ? -21.960 -41.114 -35.694 1.00 36.61  ? 39  TYR B CG  1 
ATOM   3892  C CD1 . TYR B 1 39  ? -21.349 -41.386 -36.904 1.00 37.44  ? 39  TYR B CD1 1 
ATOM   3893  C CD2 . TYR B 1 39  ? -22.740 -39.974 -35.587 1.00 35.42  ? 39  TYR B CD2 1 
ATOM   3894  C CE1 . TYR B 1 39  ? -21.551 -40.564 -37.997 1.00 43.44  ? 39  TYR B CE1 1 
ATOM   3895  C CE2 . TYR B 1 39  ? -22.918 -39.128 -36.661 1.00 39.91  ? 39  TYR B CE2 1 
ATOM   3896  C CZ  . TYR B 1 39  ? -22.337 -39.430 -37.874 1.00 41.82  ? 39  TYR B CZ  1 
ATOM   3897  O OH  . TYR B 1 39  ? -22.528 -38.558 -38.918 1.00 45.13  ? 39  TYR B OH  1 
ATOM   3898  N N   . GLY B 1 40  ? -19.675 -43.186 -31.994 1.00 36.58  ? 40  GLY B N   1 
ATOM   3899  C CA  . GLY B 1 40  ? -19.765 -44.018 -30.803 1.00 37.51  ? 40  GLY B CA  1 
ATOM   3900  C C   . GLY B 1 40  ? -18.608 -43.761 -29.836 1.00 37.17  ? 40  GLY B C   1 
ATOM   3901  O O   . GLY B 1 40  ? -18.243 -44.628 -29.064 1.00 38.45  ? 40  GLY B O   1 
ATOM   3902  N N   . GLY B 1 41  ? -18.034 -42.558 -29.876 1.00 38.25  ? 41  GLY B N   1 
ATOM   3903  C CA  . GLY B 1 41  ? -16.986 -42.192 -28.936 1.00 41.31  ? 41  GLY B CA  1 
ATOM   3904  C C   . GLY B 1 41  ? -15.738 -43.075 -29.031 1.00 40.17  ? 41  GLY B C   1 
ATOM   3905  O O   . GLY B 1 41  ? -15.069 -43.304 -28.021 1.00 36.85  ? 41  GLY B O   1 
ATOM   3906  N N   . MET B 1 42  ? -15.422 -43.552 -30.245 1.00 33.22  ? 42  MET B N   1 
ATOM   3907  C CA  . MET B 1 42  ? -14.160 -44.214 -30.541 1.00 34.60  ? 42  MET B CA  1 
ATOM   3908  C C   . MET B 1 42  ? -14.021 -45.511 -29.752 1.00 33.26  ? 42  MET B C   1 
ATOM   3909  O O   . MET B 1 42  ? -12.899 -45.974 -29.530 1.00 33.56  ? 42  MET B O   1 
ATOM   3910  C CB  . MET B 1 42  ? -12.971 -43.346 -30.108 1.00 38.88  ? 42  MET B CB  1 
ATOM   3911  C CG  . MET B 1 42  ? -12.757 -42.100 -30.875 1.00 40.18  ? 42  MET B CG  1 
ATOM   3912  S SD  . MET B 1 42  ? -11.138 -41.408 -30.435 1.00 43.94  ? 42  MET B SD  1 
ATOM   3913  C CE  . MET B 1 42  ? -11.446 -39.686 -30.814 1.00 42.26  ? 42  MET B CE  1 
ATOM   3914  N N   . ARG B 1 43  ? -15.130 -46.070 -29.276 1.00 36.51  ? 43  ARG B N   1 
ATOM   3915  C CA  . ARG B 1 43  ? -15.063 -47.210 -28.377 1.00 39.32  ? 43  ARG B CA  1 
ATOM   3916  C C   . ARG B 1 43  ? -14.270 -48.334 -29.046 1.00 44.23  ? 43  ARG B C   1 
ATOM   3917  O O   . ARG B 1 43  ? -14.611 -48.765 -30.134 1.00 41.34  ? 43  ARG B O   1 
ATOM   3918  C CB  . ARG B 1 43  ? -16.483 -47.650 -28.005 1.00 42.44  ? 43  ARG B CB  1 
ATOM   3919  C CG  . ARG B 1 43  ? -16.601 -48.620 -26.827 1.00 51.02  ? 43  ARG B CG  1 
ATOM   3920  C CD  . ARG B 1 43  ? -16.675 -48.041 -25.402 1.00 60.18  ? 43  ARG B CD  1 
ATOM   3921  N NE  . ARG B 1 43  ? -17.700 -47.007 -25.128 1.00 62.53  ? 43  ARG B NE  1 
ATOM   3922  C CZ  . ARG B 1 43  ? -17.581 -45.697 -25.399 1.00 69.83  ? 43  ARG B CZ  1 
ATOM   3923  N NH1 . ARG B 1 43  ? -16.403 -45.183 -25.708 1.00 76.54  ? 43  ARG B NH1 1 
ATOM   3924  N NH2 . ARG B 1 43  ? -18.632 -44.888 -25.355 1.00 64.10  ? 43  ARG B NH2 1 
ATOM   3925  N N   . GLY B 1 44  ? -13.166 -48.773 -28.420 1.00 47.17  ? 44  GLY B N   1 
ATOM   3926  C CA  . GLY B 1 44  ? -12.395 -49.914 -28.901 1.00 44.26  ? 44  GLY B CA  1 
ATOM   3927  C C   . GLY B 1 44  ? -11.357 -49.538 -29.954 1.00 42.16  ? 44  GLY B C   1 
ATOM   3928  O O   . GLY B 1 44  ? -10.534 -50.362 -30.313 1.00 43.51  ? 44  GLY B O   1 
ATOM   3929  N N   . LEU B 1 45  ? -11.352 -48.282 -30.420 1.00 38.05  ? 45  LEU B N   1 
ATOM   3930  C CA  . LEU B 1 45  ? -10.425 -47.899 -31.471 1.00 39.18  ? 45  LEU B CA  1 
ATOM   3931  C C   . LEU B 1 45  ? -9.018  -47.728 -30.889 1.00 43.15  ? 45  LEU B C   1 
ATOM   3932  O O   . LEU B 1 45  ? -8.821  -46.971 -29.934 1.00 38.43  ? 45  LEU B O   1 
ATOM   3933  C CB  . LEU B 1 45  ? -10.957 -46.632 -32.149 1.00 37.23  ? 45  LEU B CB  1 
ATOM   3934  C CG  . LEU B 1 45  ? -10.210 -46.204 -33.404 1.00 43.25  ? 45  LEU B CG  1 
ATOM   3935  C CD1 . LEU B 1 45  ? -10.362 -47.260 -34.494 1.00 45.89  ? 45  LEU B CD1 1 
ATOM   3936  C CD2 . LEU B 1 45  ? -10.726 -44.852 -33.898 1.00 45.57  ? 45  LEU B CD2 1 
ATOM   3937  N N   . LYS B 1 46  ? -8.027  -48.431 -31.461 1.00 38.06  ? 46  LYS B N   1 
ATOM   3938  C CA  . LYS B 1 46  ? -6.691  -48.467 -30.873 1.00 34.50  ? 46  LYS B CA  1 
ATOM   3939  C C   . LYS B 1 46  ? -5.894  -47.230 -31.295 1.00 36.93  ? 46  LYS B C   1 
ATOM   3940  O O   . LYS B 1 46  ? -5.040  -47.276 -32.175 1.00 37.06  ? 46  LYS B O   1 
ATOM   3941  C CB  . LYS B 1 46  ? -5.999  -49.783 -31.237 1.00 37.24  ? 46  LYS B CB  1 
ATOM   3942  C CG  . LYS B 1 46  ? -6.639  -51.031 -30.649 1.00 38.22  ? 46  LYS B CG  1 
ATOM   3943  C CD  . LYS B 1 46  ? -5.678  -52.217 -30.692 1.00 45.78  ? 46  LYS B CD  1 
ATOM   3944  C CE  . LYS B 1 46  ? -6.306  -53.523 -31.108 1.00 52.45  ? 46  LYS B CE  1 
ATOM   3945  N NZ  . LYS B 1 46  ? -7.047  -54.164 -30.010 1.00 54.25  ? 46  LYS B NZ  1 
ATOM   3946  N N   . ALA B 1 47  ? -6.173  -46.097 -30.636 1.00 37.64  ? 47  ALA B N   1 
ATOM   3947  C CA  . ALA B 1 47  ? -5.827  -44.797 -31.178 1.00 38.38  ? 47  ALA B CA  1 
ATOM   3948  C C   . ALA B 1 47  ? -4.767  -44.050 -30.357 1.00 37.44  ? 47  ALA B C   1 
ATOM   3949  O O   . ALA B 1 47  ? -4.380  -42.955 -30.757 1.00 39.41  ? 47  ALA B O   1 
ATOM   3950  C CB  . ALA B 1 47  ? -7.120  -44.019 -31.292 1.00 38.15  ? 47  ALA B CB  1 
ATOM   3951  N N   . LEU B 1 48  ? -4.302  -44.610 -29.226 1.00 36.35  ? 48  LEU B N   1 
ATOM   3952  C CA  . LEU B 1 48  ? -3.396  -43.916 -28.313 1.00 40.26  ? 48  LEU B CA  1 
ATOM   3953  C C   . LEU B 1 48  ? -2.331  -44.891 -27.824 1.00 34.51  ? 48  LEU B C   1 
ATOM   3954  O O   . LEU B 1 48  ? -2.597  -46.072 -27.772 1.00 34.34  ? 48  LEU B O   1 
ATOM   3955  C CB  . LEU B 1 48  ? -4.148  -43.429 -27.064 1.00 41.36  ? 48  LEU B CB  1 
ATOM   3956  C CG  . LEU B 1 48  ? -5.201  -42.345 -27.236 1.00 48.47  ? 48  LEU B CG  1 
ATOM   3957  C CD1 . LEU B 1 48  ? -5.995  -42.198 -25.955 1.00 50.76  ? 48  LEU B CD1 1 
ATOM   3958  C CD2 . LEU B 1 48  ? -4.561  -41.021 -27.606 1.00 55.58  ? 48  LEU B CD2 1 
ATOM   3959  N N   . VAL B 1 49  ? -1.209  -44.354 -27.321 1.00 36.65  ? 49  VAL B N   1 
ATOM   3960  C CA  . VAL B 1 49  ? -0.184  -45.142 -26.654 1.00 39.70  ? 49  VAL B CA  1 
ATOM   3961  C C   . VAL B 1 49  ? -0.156  -44.834 -25.156 1.00 36.74  ? 49  VAL B C   1 
ATOM   3962  O O   . VAL B 1 49  ? -0.168  -43.672 -24.743 1.00 39.60  ? 49  VAL B O   1 
ATOM   3963  C CB  . VAL B 1 49  ? 1.201   -44.932 -27.285 1.00 39.88  ? 49  VAL B CB  1 
ATOM   3964  C CG1 . VAL B 1 49  ? 2.283   -45.714 -26.545 1.00 47.97  ? 49  VAL B CG1 1 
ATOM   3965  C CG2 . VAL B 1 49  ? 1.184   -45.353 -28.742 1.00 44.58  ? 49  VAL B CG2 1 
ATOM   3966  N N   . CYS B 1 50  ? -0.097  -45.899 -24.358 1.00 36.73  ? 50  CYS B N   1 
ATOM   3967  C CA  . CYS B 1 50  ? 0.185   -45.815 -22.920 1.00 39.57  ? 50  CYS B CA  1 
ATOM   3968  C C   . CYS B 1 50  ? 1.029   -47.024 -22.475 1.00 35.83  ? 50  CYS B C   1 
ATOM   3969  O O   . CYS B 1 50  ? 0.586   -48.166 -22.628 1.00 40.31  ? 50  CYS B O   1 
ATOM   3970  C CB  . CYS B 1 50  ? -1.115  -45.740 -22.116 1.00 36.02  ? 50  CYS B CB  1 
ATOM   3971  S SG  . CYS B 1 50  ? -0.890  -45.851 -20.304 1.00 40.43  ? 50  CYS B SG  1 
ATOM   3972  N N   . ASP B 1 51  ? 2.200   -46.754 -21.867 1.00 33.82  ? 51  ASP B N   1 
ATOM   3973  C CA  . ASP B 1 51  ? 3.125   -47.781 -21.400 1.00 32.70  ? 51  ASP B CA  1 
ATOM   3974  C C   . ASP B 1 51  ? 3.159   -47.917 -19.880 1.00 37.72  ? 51  ASP B C   1 
ATOM   3975  O O   . ASP B 1 51  ? 3.872   -48.780 -19.379 1.00 39.17  ? 51  ASP B O   1 
ATOM   3976  C CB  . ASP B 1 51  ? 4.534   -47.487 -21.915 1.00 35.82  ? 51  ASP B CB  1 
ATOM   3977  C CG  . ASP B 1 51  ? 4.700   -47.907 -23.367 1.00 36.00  ? 51  ASP B CG  1 
ATOM   3978  O OD1 . ASP B 1 51  ? 4.042   -48.887 -23.718 1.00 35.63  ? 51  ASP B OD1 1 
ATOM   3979  O OD2 . ASP B 1 51  ? 5.422   -47.204 -24.138 1.00 37.67  ? 51  ASP B OD2 1 
ATOM   3980  N N   . THR B 1 52  ? 2.416   -47.083 -19.133 1.00 31.94  ? 52  THR B N   1 
ATOM   3981  C CA  . THR B 1 52  ? 2.506   -47.150 -17.674 1.00 37.21  ? 52  THR B CA  1 
ATOM   3982  C C   . THR B 1 52  ? 1.732   -48.352 -17.139 1.00 38.54  ? 52  THR B C   1 
ATOM   3983  O O   . THR B 1 52  ? 2.143   -48.978 -16.161 1.00 38.35  ? 52  THR B O   1 
ATOM   3984  C CB  . THR B 1 52  ? 2.039   -45.837 -17.036 1.00 33.83  ? 52  THR B CB  1 
ATOM   3985  O OG1 . THR B 1 52  ? 0.742   -45.488 -17.536 1.00 31.92  ? 52  THR B OG1 1 
ATOM   3986  C CG2 . THR B 1 52  ? 3.011   -44.729 -17.368 1.00 37.45  ? 52  THR B CG2 1 
ATOM   3987  N N   . SER B 1 53  ? 0.574   -48.615 -17.758 1.00 36.96  ? 53  SER B N   1 
ATOM   3988  C CA  . SER B 1 53  ? -0.305  -49.675 -17.319 1.00 32.71  ? 53  SER B CA  1 
ATOM   3989  C C   . SER B 1 53  ? -1.047  -50.268 -18.521 1.00 39.28  ? 53  SER B C   1 
ATOM   3990  O O   . SER B 1 53  ? -1.073  -49.701 -19.611 1.00 39.15  ? 53  SER B O   1 
ATOM   3991  C CB  . SER B 1 53  ? -1.241  -49.187 -16.245 1.00 36.15  ? 53  SER B CB  1 
ATOM   3992  O OG  . SER B 1 53  ? -2.153  -48.221 -16.737 1.00 37.14  ? 53  SER B OG  1 
ATOM   3993  N N   . GLU B 1 54  ? -1.668  -51.427 -18.304 1.00 38.19  ? 54  GLU B N   1 
ATOM   3994  C CA  . GLU B 1 54  ? -2.177  -52.269 -19.379 1.00 38.19  ? 54  GLU B CA  1 
ATOM   3995  C C   . GLU B 1 54  ? -3.171  -53.219 -18.741 1.00 35.78  ? 54  GLU B C   1 
ATOM   3996  O O   . GLU B 1 54  ? -2.850  -53.871 -17.741 1.00 34.85  ? 54  GLU B O   1 
ATOM   3997  C CB  . GLU B 1 54  ? -1.052  -53.041 -20.086 1.00 40.84  ? 54  GLU B CB  1 
ATOM   3998  C CG  . GLU B 1 54  ? -1.521  -53.895 -21.263 1.00 44.90  ? 54  GLU B CG  1 
ATOM   3999  C CD  . GLU B 1 54  ? -0.452  -54.482 -22.187 1.00 47.91  ? 54  GLU B CD  1 
ATOM   4000  O OE1 . GLU B 1 54  ? -0.829  -54.829 -23.320 1.00 56.31  ? 54  GLU B OE1 1 
ATOM   4001  O OE2 . GLU B 1 54  ? 0.763   -54.586 -21.798 1.00 47.46  ? 54  GLU B OE2 1 
ATOM   4002  N N   . VAL B 1 55  ? -4.344  -53.290 -19.352 1.00 38.91  ? 55  VAL B N   1 
ATOM   4003  C CA  . VAL B 1 55  ? -5.433  -54.103 -18.859 1.00 43.07  ? 55  VAL B CA  1 
ATOM   4004  C C   . VAL B 1 55  ? -5.430  -55.429 -19.613 1.00 45.27  ? 55  VAL B C   1 
ATOM   4005  O O   . VAL B 1 55  ? -5.540  -55.424 -20.834 1.00 46.39  ? 55  VAL B O   1 
ATOM   4006  C CB  . VAL B 1 55  ? -6.772  -53.368 -19.056 1.00 43.80  ? 55  VAL B CB  1 
ATOM   4007  C CG1 . VAL B 1 55  ? -7.973  -54.298 -18.916 1.00 44.05  ? 55  VAL B CG1 1 
ATOM   4008  C CG2 . VAL B 1 55  ? -6.873  -52.202 -18.110 1.00 47.82  ? 55  VAL B CG2 1 
ATOM   4009  N N   . PHE B 1 56  ? -5.333  -56.554 -18.888 1.00 41.06  ? 56  PHE B N   1 
ATOM   4010  C CA  . PHE B 1 56  ? -5.575  -57.853 -19.488 1.00 44.80  ? 56  PHE B CA  1 
ATOM   4011  C C   . PHE B 1 56  ? -6.931  -58.380 -19.061 1.00 46.62  ? 56  PHE B C   1 
ATOM   4012  O O   . PHE B 1 56  ? -7.201  -58.441 -17.864 1.00 46.47  ? 56  PHE B O   1 
ATOM   4013  C CB  . PHE B 1 56  ? -4.470  -58.813 -19.073 1.00 46.35  ? 56  PHE B CB  1 
ATOM   4014  C CG  . PHE B 1 56  ? -3.114  -58.364 -19.531 1.00 48.63  ? 56  PHE B CG  1 
ATOM   4015  C CD1 . PHE B 1 56  ? -2.432  -57.366 -18.849 1.00 48.34  ? 56  PHE B CD1 1 
ATOM   4016  C CD2 . PHE B 1 56  ? -2.554  -58.897 -20.686 1.00 53.99  ? 56  PHE B CD2 1 
ATOM   4017  C CE1 . PHE B 1 56  ? -1.173  -56.958 -19.276 1.00 51.69  ? 56  PHE B CE1 1 
ATOM   4018  C CE2 . PHE B 1 56  ? -1.297  -58.491 -21.115 1.00 57.25  ? 56  PHE B CE2 1 
ATOM   4019  C CZ  . PHE B 1 56  ? -0.611  -57.518 -20.413 1.00 53.65  ? 56  PHE B CZ  1 
ATOM   4020  N N   . PRO B 1 57  ? -7.805  -58.796 -20.007 1.00 50.28  ? 57  PRO B N   1 
ATOM   4021  C CA  . PRO B 1 57  ? -9.137  -59.318 -19.667 1.00 49.44  ? 57  PRO B CA  1 
ATOM   4022  C C   . PRO B 1 57  ? -9.194  -60.406 -18.585 1.00 50.72  ? 57  PRO B C   1 
ATOM   4023  O O   . PRO B 1 57  ? -10.125 -60.392 -17.762 1.00 49.18  ? 57  PRO B O   1 
ATOM   4024  C CB  . PRO B 1 57  ? -9.634  -59.852 -21.023 1.00 49.67  ? 57  PRO B CB  1 
ATOM   4025  C CG  . PRO B 1 57  ? -8.998  -58.927 -22.024 1.00 47.46  ? 57  PRO B CG  1 
ATOM   4026  C CD  . PRO B 1 57  ? -7.610  -58.683 -21.465 1.00 51.66  ? 57  PRO B CD  1 
ATOM   4027  N N   . ASP B 1 58  ? -8.168  -61.283 -18.558 1.00 41.12  ? 58  ASP B N   1 
ATOM   4028  C CA  . ASP B 1 58  ? -8.069  -62.374 -17.592 1.00 52.82  ? 58  ASP B CA  1 
ATOM   4029  C C   . ASP B 1 58  ? -7.250  -62.059 -16.337 1.00 54.71  ? 58  ASP B C   1 
ATOM   4030  O O   . ASP B 1 58  ? -7.025  -62.975 -15.549 1.00 47.07  ? 58  ASP B O   1 
ATOM   4031  C CB  . ASP B 1 58  ? -7.397  -63.601 -18.218 1.00 57.27  ? 58  ASP B CB  1 
ATOM   4032  C CG  . ASP B 1 58  ? -8.274  -64.275 -19.255 1.00 69.43  ? 58  ASP B CG  1 
ATOM   4033  O OD1 . ASP B 1 58  ? -9.490  -63.954 -19.295 1.00 75.66  ? 58  ASP B OD1 1 
ATOM   4034  O OD2 . ASP B 1 58  ? -7.738  -65.107 -20.017 1.00 81.23  ? 58  ASP B OD2 1 
ATOM   4035  N N   . GLU B 1 59  ? -6.776  -60.818 -16.145 1.00 53.29  ? 59  GLU B N   1 
ATOM   4036  C CA  . GLU B 1 59  ? -5.963  -60.499 -14.970 1.00 48.03  ? 59  GLU B CA  1 
ATOM   4037  C C   . GLU B 1 59  ? -6.316  -59.146 -14.365 1.00 42.92  ? 59  GLU B C   1 
ATOM   4038  O O   . GLU B 1 59  ? -6.122  -58.948 -13.169 1.00 42.04  ? 59  GLU B O   1 
ATOM   4039  C CB  . GLU B 1 59  ? -4.480  -60.422 -15.306 1.00 45.71  ? 59  GLU B CB  1 
ATOM   4040  C CG  . GLU B 1 59  ? -3.967  -61.659 -15.993 1.00 53.51  ? 59  GLU B CG  1 
ATOM   4041  C CD  . GLU B 1 59  ? -2.456  -61.717 -16.099 1.00 53.22  ? 59  GLU B CD  1 
ATOM   4042  O OE1 . GLU B 1 59  ? -1.793  -61.682 -15.034 1.00 52.41  ? 59  GLU B OE1 1 
ATOM   4043  O OE2 . GLU B 1 59  ? -1.955  -61.803 -17.241 1.00 62.63  ? 59  GLU B OE2 1 
ATOM   4044  N N   . GLY B 1 60  ? -6.860  -58.229 -15.176 1.00 42.99  ? 60  GLY B N   1 
ATOM   4045  C CA  . GLY B 1 60  ? -7.032  -56.848 -14.752 1.00 40.93  ? 60  GLY B CA  1 
ATOM   4046  C C   . GLY B 1 60  ? -5.776  -56.024 -15.027 1.00 43.11  ? 60  GLY B C   1 
ATOM   4047  O O   . GLY B 1 60  ? -4.948  -56.397 -15.867 1.00 40.32  ? 60  GLY B O   1 
ATOM   4048  N N   . VAL B 1 61  ? -5.633  -54.902 -14.302 1.00 37.29  ? 61  VAL B N   1 
ATOM   4049  C CA  . VAL B 1 61  ? -4.689  -53.902 -14.729 1.00 32.42  ? 61  VAL B CA  1 
ATOM   4050  C C   . VAL B 1 61  ? -3.360  -54.418 -14.217 1.00 37.71  ? 61  VAL B C   1 
ATOM   4051  O O   . VAL B 1 61  ? -3.299  -54.983 -13.129 1.00 42.23  ? 61  VAL B O   1 
ATOM   4052  C CB  . VAL B 1 61  ? -5.046  -52.477 -14.220 1.00 38.39  ? 61  VAL B CB  1 
ATOM   4053  C CG1 . VAL B 1 61  ? -5.117  -52.348 -12.698 1.00 34.89  ? 61  VAL B CG1 1 
ATOM   4054  C CG2 . VAL B 1 61  ? -4.088  -51.446 -14.781 1.00 34.92  ? 61  VAL B CG2 1 
ATOM   4055  N N   . LYS B 1 62  ? -2.316  -54.245 -15.008 1.00 33.96  ? 62  LYS B N   1 
ATOM   4056  C CA  . LYS B 1 62  ? -0.966  -54.378 -14.501 1.00 34.02  ? 62  LYS B CA  1 
ATOM   4057  C C   . LYS B 1 62  ? -0.228  -53.060 -14.635 1.00 35.68  ? 62  LYS B C   1 
ATOM   4058  O O   . LYS B 1 62  ? -0.485  -52.321 -15.583 1.00 36.57  ? 62  LYS B O   1 
ATOM   4059  C CB  . LYS B 1 62  ? -0.215  -55.480 -15.252 1.00 41.54  ? 62  LYS B CB  1 
ATOM   4060  C CG  . LYS B 1 62  ? -0.915  -56.835 -15.178 1.00 47.41  ? 62  LYS B CG  1 
ATOM   4061  C CD  . LYS B 1 62  ? 0.010   -58.033 -15.203 1.00 55.36  ? 62  LYS B CD  1 
ATOM   4062  C CE  . LYS B 1 62  ? 0.637   -58.299 -16.552 1.00 63.67  ? 62  LYS B CE  1 
ATOM   4063  N NZ  . LYS B 1 62  ? 0.971   -59.737 -16.722 1.00 64.70  ? 62  LYS B NZ  1 
ATOM   4064  N N   . PHE B 1 63  ? 0.739   -52.866 -13.729 1.00 32.71  ? 63  PHE B N   1 
ATOM   4065  C CA  . PHE B 1 63  ? 1.572   -51.692 -13.685 1.00 38.88  ? 63  PHE B CA  1 
ATOM   4066  C C   . PHE B 1 63  ? 2.991   -52.061 -14.102 1.00 39.16  ? 63  PHE B C   1 
ATOM   4067  O O   . PHE B 1 63  ? 3.706   -52.716 -13.345 1.00 39.55  ? 63  PHE B O   1 
ATOM   4068  C CB  . PHE B 1 63  ? 1.571   -51.118 -12.261 1.00 38.51  ? 63  PHE B CB  1 
ATOM   4069  C CG  . PHE B 1 63  ? 0.240   -50.668 -11.714 1.00 37.02  ? 63  PHE B CG  1 
ATOM   4070  C CD1 . PHE B 1 63  ? -0.585  -49.822 -12.440 1.00 39.87  ? 63  PHE B CD1 1 
ATOM   4071  C CD2 . PHE B 1 63  ? -0.133  -50.970 -10.414 1.00 42.14  ? 63  PHE B CD2 1 
ATOM   4072  C CE1 . PHE B 1 63  ? -1.796  -49.382 -11.922 1.00 44.01  ? 63  PHE B CE1 1 
ATOM   4073  C CE2 . PHE B 1 63  ? -1.328  -50.503 -9.882  1.00 46.82  ? 63  PHE B CE2 1 
ATOM   4074  C CZ  . PHE B 1 63  ? -2.159  -49.708 -10.636 1.00 48.35  ? 63  PHE B CZ  1 
ATOM   4075  N N   . ARG B 1 64  ? 3.389   -51.608 -15.294 1.00 34.10  ? 64  ARG B N   1 
ATOM   4076  C CA  . ARG B 1 64  ? 4.671   -51.928 -15.893 1.00 36.20  ? 64  ARG B CA  1 
ATOM   4077  C C   . ARG B 1 64  ? 4.952   -53.429 -15.813 1.00 36.62  ? 64  ARG B C   1 
ATOM   4078  O O   . ARG B 1 64  ? 6.099   -53.855 -15.641 1.00 38.76  ? 64  ARG B O   1 
ATOM   4079  C CB  . ARG B 1 64  ? 5.775   -51.088 -15.268 1.00 37.44  ? 64  ARG B CB  1 
ATOM   4080  C CG  . ARG B 1 64  ? 5.680   -49.626 -15.673 1.00 38.94  ? 64  ARG B CG  1 
ATOM   4081  C CD  . ARG B 1 64  ? 6.096   -49.429 -17.097 1.00 38.18  ? 64  ARG B CD  1 
ATOM   4082  N NE  . ARG B 1 64  ? 6.660   -48.115 -17.263 1.00 38.48  ? 64  ARG B NE  1 
ATOM   4083  C CZ  . ARG B 1 64  ? 7.306   -47.740 -18.352 1.00 40.81  ? 64  ARG B CZ  1 
ATOM   4084  N NH1 . ARG B 1 64  ? 7.461   -48.581 -19.360 1.00 40.65  ? 64  ARG B NH1 1 
ATOM   4085  N NH2 . ARG B 1 64  ? 7.769   -46.518 -18.452 1.00 41.74  ? 64  ARG B NH2 1 
ATOM   4086  N N   . GLY B 1 65  ? 3.902   -54.215 -16.020 1.00 34.66  ? 65  GLY B N   1 
ATOM   4087  C CA  . GLY B 1 65  ? 4.060   -55.651 -16.160 1.00 41.83  ? 65  GLY B CA  1 
ATOM   4088  C C   . GLY B 1 65  ? 3.919   -56.389 -14.835 1.00 45.94  ? 65  GLY B C   1 
ATOM   4089  O O   . GLY B 1 65  ? 4.030   -57.603 -14.827 1.00 49.60  ? 65  GLY B O   1 
ATOM   4090  N N   . TYR B 1 66  ? 3.719   -55.664 -13.721 1.00 43.20  ? 66  TYR B N   1 
ATOM   4091  C CA  . TYR B 1 66  ? 3.563   -56.306 -12.416 1.00 42.61  ? 66  TYR B CA  1 
ATOM   4092  C C   . TYR B 1 66  ? 2.095   -56.254 -11.985 1.00 41.33  ? 66  TYR B C   1 
ATOM   4093  O O   . TYR B 1 66  ? 1.386   -55.305 -12.306 1.00 43.55  ? 66  TYR B O   1 
ATOM   4094  C CB  . TYR B 1 66  ? 4.475   -55.674 -11.370 1.00 40.31  ? 66  TYR B CB  1 
ATOM   4095  C CG  . TYR B 1 66  ? 5.959   -55.802 -11.618 1.00 44.03  ? 66  TYR B CG  1 
ATOM   4096  C CD1 . TYR B 1 66  ? 6.683   -56.892 -11.142 1.00 42.16  ? 66  TYR B CD1 1 
ATOM   4097  C CD2 . TYR B 1 66  ? 6.644   -54.823 -12.319 1.00 41.25  ? 66  TYR B CD2 1 
ATOM   4098  C CE1 . TYR B 1 66  ? 8.044   -57.003 -11.373 1.00 44.55  ? 66  TYR B CE1 1 
ATOM   4099  C CE2 . TYR B 1 66  ? 8.015   -54.906 -12.537 1.00 45.03  ? 66  TYR B CE2 1 
ATOM   4100  C CZ  . TYR B 1 66  ? 8.715   -56.000 -12.061 1.00 45.98  ? 66  TYR B CZ  1 
ATOM   4101  O OH  . TYR B 1 66  ? 10.065  -56.054 -12.257 1.00 42.14  ? 66  TYR B OH  1 
ATOM   4102  N N   . THR B 1 67  ? 1.640   -57.317 -11.318 1.00 34.30  ? 67  THR B N   1 
ATOM   4103  C CA  . THR B 1 67  ? 0.270   -57.437 -10.848 1.00 37.55  ? 67  THR B CA  1 
ATOM   4104  C C   . THR B 1 67  ? 0.195   -56.691 -9.520  1.00 38.48  ? 67  THR B C   1 
ATOM   4105  O O   . THR B 1 67  ? 1.229   -56.451 -8.890  1.00 39.35  ? 67  THR B O   1 
ATOM   4106  C CB  . THR B 1 67  ? -0.176  -58.900 -10.643 1.00 37.17  ? 67  THR B CB  1 
ATOM   4107  O OG1 . THR B 1 67  ? 0.580   -59.402 -9.541  1.00 35.03  ? 67  THR B OG1 1 
ATOM   4108  C CG2 . THR B 1 67  ? 0.029   -59.797 -11.844 1.00 41.56  ? 67  THR B CG2 1 
ATOM   4109  N N   . ILE B 1 68  ? -1.032  -56.379 -9.088  1.00 34.68  ? 68  ILE B N   1 
ATOM   4110  C CA  . ILE B 1 68  ? -1.227  -55.693 -7.821  1.00 40.84  ? 68  ILE B CA  1 
ATOM   4111  C C   . ILE B 1 68  ? -0.710  -56.591 -6.688  1.00 38.07  ? 68  ILE B C   1 
ATOM   4112  O O   . ILE B 1 68  ? 0.154   -56.155 -5.907  1.00 37.13  ? 68  ILE B O   1 
ATOM   4113  C CB  . ILE B 1 68  ? -2.710  -55.253 -7.691  1.00 42.51  ? 68  ILE B CB  1 
ATOM   4114  C CG1 . ILE B 1 68  ? -2.975  -53.971 -8.491  1.00 40.91  ? 68  ILE B CG1 1 
ATOM   4115  C CG2 . ILE B 1 68  ? -3.119  -55.110 -6.229  1.00 40.66  ? 68  ILE B CG2 1 
ATOM   4116  C CD1 . ILE B 1 68  ? -4.441  -53.703 -8.786  1.00 42.84  ? 68  ILE B CD1 1 
ATOM   4117  N N   . PRO B 1 69  ? -1.152  -57.875 -6.600  1.00 43.84  ? 69  PRO B N   1 
ATOM   4118  C CA  . PRO B 1 69  ? -0.603  -58.830 -5.629  1.00 43.13  ? 69  PRO B CA  1 
ATOM   4119  C C   . PRO B 1 69  ? 0.922   -58.928 -5.586  1.00 40.85  ? 69  PRO B C   1 
ATOM   4120  O O   . PRO B 1 69  ? 1.474   -58.974 -4.503  1.00 40.61  ? 69  PRO B O   1 
ATOM   4121  C CB  . PRO B 1 69  ? -1.224  -60.153 -6.069  1.00 45.49  ? 69  PRO B CB  1 
ATOM   4122  C CG  . PRO B 1 69  ? -2.574  -59.728 -6.581  1.00 48.26  ? 69  PRO B CG  1 
ATOM   4123  C CD  . PRO B 1 69  ? -2.231  -58.494 -7.393  1.00 46.98  ? 69  PRO B CD  1 
ATOM   4124  N N   . GLU B 1 70  ? 1.621   -58.946 -6.720  1.00 39.70  ? 70  GLU B N   1 
ATOM   4125  C CA  . GLU B 1 70  ? 3.086   -58.987 -6.664  1.00 46.17  ? 70  GLU B CA  1 
ATOM   4126  C C   . GLU B 1 70  ? 3.672   -57.763 -5.936  1.00 45.92  ? 70  GLU B C   1 
ATOM   4127  O O   . GLU B 1 70  ? 4.644   -57.892 -5.186  1.00 38.02  ? 70  GLU B O   1 
ATOM   4128  C CB  . GLU B 1 70  ? 3.707   -59.035 -8.060  1.00 51.31  ? 70  GLU B CB  1 
ATOM   4129  C CG  . GLU B 1 70  ? 3.527   -60.358 -8.792  1.00 58.41  ? 70  GLU B CG  1 
ATOM   4130  C CD  . GLU B 1 70  ? 4.100   -60.359 -10.206 1.00 62.72  ? 70  GLU B CD  1 
ATOM   4131  O OE1 . GLU B 1 70  ? 4.967   -61.216 -10.480 1.00 80.16  ? 70  GLU B OE1 1 
ATOM   4132  O OE2 . GLU B 1 70  ? 3.714   -59.474 -11.024 1.00 55.39  ? 70  GLU B OE2 1 
ATOM   4133  N N   . LEU B 1 71  ? 3.096   -56.569 -6.183  1.00 41.00  ? 71  LEU B N   1 
ATOM   4134  C CA  . LEU B 1 71  ? 3.587   -55.310 -5.607  1.00 40.89  ? 71  LEU B CA  1 
ATOM   4135  C C   . LEU B 1 71  ? 3.107   -55.105 -4.161  1.00 40.12  ? 71  LEU B C   1 
ATOM   4136  O O   . LEU B 1 71  ? 3.772   -54.447 -3.355  1.00 34.96  ? 71  LEU B O   1 
ATOM   4137  C CB  . LEU B 1 71  ? 3.096   -54.169 -6.496  1.00 37.45  ? 71  LEU B CB  1 
ATOM   4138  C CG  . LEU B 1 71  ? 3.593   -54.197 -7.940  1.00 35.03  ? 71  LEU B CG  1 
ATOM   4139  C CD1 . LEU B 1 71  ? 2.880   -53.159 -8.768  1.00 42.52  ? 71  LEU B CD1 1 
ATOM   4140  C CD2 . LEU B 1 71  ? 5.109   -53.973 -8.007  1.00 36.43  ? 71  LEU B CD2 1 
ATOM   4141  N N   . ARG B 1 72  ? 1.922   -55.651 -3.852  1.00 36.22  ? 72  ARG B N   1 
ATOM   4142  C CA  . ARG B 1 72  ? 1.260   -55.437 -2.582  1.00 40.34  ? 72  ARG B CA  1 
ATOM   4143  C C   . ARG B 1 72  ? 1.671   -56.482 -1.527  1.00 44.60  ? 72  ARG B C   1 
ATOM   4144  O O   . ARG B 1 72  ? 1.757   -56.190 -0.325  1.00 42.63  ? 72  ARG B O   1 
ATOM   4145  C CB  . ARG B 1 72  ? -0.246  -55.468 -2.835  1.00 40.68  ? 72  ARG B CB  1 
ATOM   4146  C CG  . ARG B 1 72  ? -1.035  -55.297 -1.551  1.00 46.42  ? 72  ARG B CG  1 
ATOM   4147  C CD  . ARG B 1 72  ? -2.452  -54.848 -1.806  1.00 45.46  ? 72  ARG B CD  1 
ATOM   4148  N NE  . ARG B 1 72  ? -2.996  -54.554 -0.494  1.00 44.59  ? 72  ARG B NE  1 
ATOM   4149  C CZ  . ARG B 1 72  ? -3.673  -55.437 0.218   1.00 43.26  ? 72  ARG B CZ  1 
ATOM   4150  N NH1 . ARG B 1 72  ? -3.929  -56.604 -0.325  1.00 40.17  ? 72  ARG B NH1 1 
ATOM   4151  N NH2 . ARG B 1 72  ? -4.113  -55.147 1.433   1.00 49.80  ? 72  ARG B NH2 1 
ATOM   4152  N N   . GLU B 1 73  ? 1.858   -57.735 -1.943  1.00 47.92  ? 73  GLU B N   1 
ATOM   4153  C CA  . GLU B 1 73  ? 2.309   -58.744 -0.983  1.00 61.50  ? 73  GLU B CA  1 
ATOM   4154  C C   . GLU B 1 73  ? 3.336   -59.711 -1.554  1.00 63.05  ? 73  GLU B C   1 
ATOM   4155  O O   . GLU B 1 73  ? 4.195   -60.157 -0.807  1.00 71.58  ? 73  GLU B O   1 
ATOM   4156  C CB  . GLU B 1 73  ? 1.142   -59.576 -0.456  1.00 65.06  ? 73  GLU B CB  1 
ATOM   4157  C CG  . GLU B 1 73  ? 0.328   -60.254 -1.532  1.00 58.34  ? 73  GLU B CG  1 
ATOM   4158  C CD  . GLU B 1 73  ? -1.140  -60.196 -1.174  1.00 62.48  ? 73  GLU B CD  1 
ATOM   4159  O OE1 . GLU B 1 73  ? -1.985  -60.278 -2.080  1.00 68.83  ? 73  GLU B OE1 1 
ATOM   4160  O OE2 . GLU B 1 73  ? -1.418  -60.045 0.020   1.00 66.50  ? 73  GLU B OE2 1 
ATOM   4161  N N   . GLY B 1 74  ? 3.189   -60.068 -2.833  1.00 68.00  ? 74  GLY B N   1 
ATOM   4162  C CA  . GLY B 1 74  ? 3.888   -61.181 -3.456  1.00 72.42  ? 74  GLY B CA  1 
ATOM   4163  C C   . GLY B 1 74  ? 5.399   -61.072 -3.291  1.00 71.28  ? 74  GLY B C   1 
ATOM   4164  O O   . GLY B 1 74  ? 5.868   -60.569 -2.275  1.00 65.49  ? 74  GLY B O   1 
ATOM   4165  N N   . PRO B 1 75  ? 6.204   -61.556 -4.265  1.00 65.82  ? 75  PRO B N   1 
ATOM   4166  C CA  . PRO B 1 75  ? 7.664   -61.485 -4.146  1.00 64.19  ? 75  PRO B CA  1 
ATOM   4167  C C   . PRO B 1 75  ? 8.321   -60.180 -4.627  1.00 57.87  ? 75  PRO B C   1 
ATOM   4168  O O   . PRO B 1 75  ? 9.521   -60.005 -4.458  1.00 60.96  ? 75  PRO B O   1 
ATOM   4169  C CB  . PRO B 1 75  ? 8.099   -62.717 -4.969  1.00 62.10  ? 75  PRO B CB  1 
ATOM   4170  C CG  . PRO B 1 75  ? 7.023   -62.878 -6.050  1.00 61.99  ? 75  PRO B CG  1 
ATOM   4171  C CD  . PRO B 1 75  ? 5.760   -62.261 -5.480  1.00 70.03  ? 75  PRO B CD  1 
ATOM   4172  N N   . HIS B 1 76  ? 7.548   -59.229 -5.181  1.00 58.23  ? 76  HIS B N   1 
ATOM   4173  C CA  . HIS B 1 76  ? 8.108   -57.947 -5.611  1.00 58.32  ? 76  HIS B CA  1 
ATOM   4174  C C   . HIS B 1 76  ? 7.555   -56.770 -4.784  1.00 51.62  ? 76  HIS B C   1 
ATOM   4175  O O   . HIS B 1 76  ? 7.290   -55.689 -5.311  1.00 52.72  ? 76  HIS B O   1 
ATOM   4176  C CB  . HIS B 1 76  ? 7.884   -57.807 -7.125  1.00 61.40  ? 76  HIS B CB  1 
ATOM   4177  C CG  . HIS B 1 76  ? 8.556   -58.876 -7.943  1.00 63.38  ? 76  HIS B CG  1 
ATOM   4178  N ND1 . HIS B 1 76  ? 7.862   -59.840 -8.656  1.00 64.36  ? 76  HIS B ND1 1 
ATOM   4179  C CD2 . HIS B 1 76  ? 9.864   -59.125 -8.149  1.00 62.90  ? 76  HIS B CD2 1 
ATOM   4180  C CE1 . HIS B 1 76  ? 8.733   -60.620 -9.290  1.00 62.93  ? 76  HIS B CE1 1 
ATOM   4181  N NE2 . HIS B 1 76  ? 9.952   -60.201 -8.997  1.00 61.24  ? 76  HIS B NE2 1 
ATOM   4182  N N   . LYS B 1 77  ? 7.359   -56.953 -3.473  1.00 44.23  ? 77  LYS B N   1 
ATOM   4183  C CA  . LYS B 1 77  ? 6.510   -56.036 -2.720  1.00 42.80  ? 77  LYS B CA  1 
ATOM   4184  C C   . LYS B 1 77  ? 7.176   -54.663 -2.686  1.00 41.18  ? 77  LYS B C   1 
ATOM   4185  O O   . LYS B 1 77  ? 8.382   -54.549 -2.446  1.00 38.02  ? 77  LYS B O   1 
ATOM   4186  C CB  . LYS B 1 77  ? 6.283   -56.627 -1.335  1.00 47.24  ? 77  LYS B CB  1 
ATOM   4187  C CG  . LYS B 1 77  ? 5.435   -55.808 -0.386  1.00 50.51  ? 77  LYS B CG  1 
ATOM   4188  C CD  . LYS B 1 77  ? 5.474   -56.388 1.018   1.00 53.59  ? 77  LYS B CD  1 
ATOM   4189  C CE  . LYS B 1 77  ? 4.767   -55.520 2.037   1.00 51.72  ? 77  LYS B CE  1 
ATOM   4190  N NZ  . LYS B 1 77  ? 3.429   -55.127 1.550   1.00 52.19  ? 77  LYS B NZ  1 
ATOM   4191  N N   . LEU B 1 78  ? 6.416   -53.604 -2.978  1.00 39.24  ? 78  LEU B N   1 
ATOM   4192  C CA  . LEU B 1 78  ? 7.014   -52.276 -2.932  1.00 37.94  ? 78  LEU B CA  1 
ATOM   4193  C C   . LEU B 1 78  ? 7.201   -51.843 -1.480  1.00 38.01  ? 78  LEU B C   1 
ATOM   4194  O O   . LEU B 1 78  ? 6.495   -52.295 -0.579  1.00 35.73  ? 78  LEU B O   1 
ATOM   4195  C CB  . LEU B 1 78  ? 6.097   -51.289 -3.657  1.00 41.65  ? 78  LEU B CB  1 
ATOM   4196  C CG  . LEU B 1 78  ? 5.935   -51.497 -5.157  1.00 35.80  ? 78  LEU B CG  1 
ATOM   4197  C CD1 . LEU B 1 78  ? 4.743   -50.720 -5.674  1.00 39.87  ? 78  LEU B CD1 1 
ATOM   4198  C CD2 . LEU B 1 78  ? 7.200   -51.088 -5.886  1.00 38.32  ? 78  LEU B CD2 1 
ATOM   4199  N N   . PRO B 1 79  ? 8.163   -50.939 -1.202  1.00 40.60  ? 79  PRO B N   1 
ATOM   4200  C CA  . PRO B 1 79  ? 8.319   -50.383 0.144   1.00 39.33  ? 79  PRO B CA  1 
ATOM   4201  C C   . PRO B 1 79  ? 7.050   -49.750 0.737   1.00 42.43  ? 79  PRO B C   1 
ATOM   4202  O O   . PRO B 1 79  ? 6.226   -49.146 0.035   1.00 35.72  ? 79  PRO B O   1 
ATOM   4203  C CB  . PRO B 1 79  ? 9.412   -49.312 -0.045  1.00 40.98  ? 79  PRO B CB  1 
ATOM   4204  C CG  . PRO B 1 79  ? 10.219  -49.790 -1.269  1.00 42.69  ? 79  PRO B CG  1 
ATOM   4205  C CD  . PRO B 1 79  ? 9.160   -50.422 -2.159  1.00 43.43  ? 79  PRO B CD  1 
ATOM   4206  N N   . THR B 1 80  ? 6.943   -49.863 2.067   1.00 42.45  ? 80  THR B N   1 
ATOM   4207  C CA  . THR B 1 80  ? 5.812   -49.402 2.869   1.00 40.19  ? 80  THR B CA  1 
ATOM   4208  C C   . THR B 1 80  ? 6.268   -48.283 3.798   1.00 43.84  ? 80  THR B C   1 
ATOM   4209  O O   . THR B 1 80  ? 7.455   -47.972 3.866   1.00 41.67  ? 80  THR B O   1 
ATOM   4210  C CB  . THR B 1 80  ? 5.264   -50.548 3.734   1.00 42.89  ? 80  THR B CB  1 
ATOM   4211  O OG1 . THR B 1 80  ? 6.342   -50.885 4.625   1.00 41.53  ? 80  THR B OG1 1 
ATOM   4212  C CG2 . THR B 1 80  ? 4.790   -51.729 2.912   1.00 43.04  ? 80  THR B CG2 1 
ATOM   4213  N N   . ALA B 1 81  ? 5.315   -47.700 4.536   1.00 44.35  ? 81  ALA B N   1 
ATOM   4214  C CA  . ALA B 1 81  ? 5.666   -46.855 5.665   1.00 50.51  ? 81  ALA B CA  1 
ATOM   4215  C C   . ALA B 1 81  ? 6.287   -47.738 6.743   1.00 47.18  ? 81  ALA B C   1 
ATOM   4216  O O   . ALA B 1 81  ? 5.969   -48.922 6.807   1.00 45.31  ? 81  ALA B O   1 
ATOM   4217  C CB  . ALA B 1 81  ? 4.440   -46.130 6.186   1.00 48.21  ? 81  ALA B CB  1 
ATOM   4218  N N   . GLU B 1 82  ? 7.133   -47.151 7.600   1.00 54.33  ? 82  GLU B N   1 
ATOM   4219  C CA  . GLU B 1 82  ? 7.648   -47.853 8.774   1.00 54.99  ? 82  GLU B CA  1 
ATOM   4220  C C   . GLU B 1 82  ? 6.466   -48.467 9.517   1.00 46.98  ? 82  GLU B C   1 
ATOM   4221  O O   . GLU B 1 82  ? 5.530   -47.764 9.861   1.00 44.62  ? 82  GLU B O   1 
ATOM   4222  C CB  . GLU B 1 82  ? 8.398   -46.894 9.704   1.00 62.69  ? 82  GLU B CB  1 
ATOM   4223  C CG  . GLU B 1 82  ? 9.042   -47.581 10.908  1.00 69.79  ? 82  GLU B CG  1 
ATOM   4224  C CD  . GLU B 1 82  ? 9.438   -46.666 12.058  1.00 81.73  ? 82  GLU B CD  1 
ATOM   4225  O OE1 . GLU B 1 82  ? 10.225  -47.108 12.926  1.00 86.60  ? 82  GLU B OE1 1 
ATOM   4226  O OE2 . GLU B 1 82  ? 8.946   -45.516 12.100  1.00 87.92  ? 82  GLU B OE2 1 
ATOM   4227  N N   . GLY B 1 83  ? 6.471   -49.790 9.685   1.00 46.95  ? 83  GLY B N   1 
ATOM   4228  C CA  . GLY B 1 83  ? 5.410   -50.476 10.399  1.00 41.60  ? 83  GLY B CA  1 
ATOM   4229  C C   . GLY B 1 83  ? 4.142   -50.668 9.575   1.00 47.22  ? 83  GLY B C   1 
ATOM   4230  O O   . GLY B 1 83  ? 3.159   -51.215 10.073  1.00 45.10  ? 83  GLY B O   1 
ATOM   4231  N N   . GLY B 1 84  ? 4.169   -50.244 8.304   1.00 50.74  ? 84  GLY B N   1 
ATOM   4232  C CA  . GLY B 1 84  ? 3.001   -50.360 7.451   1.00 43.79  ? 84  GLY B CA  1 
ATOM   4233  C C   . GLY B 1 84  ? 2.981   -51.653 6.647   1.00 43.86  ? 84  GLY B C   1 
ATOM   4234  O O   . GLY B 1 84  ? 3.991   -52.332 6.506   1.00 42.67  ? 84  GLY B O   1 
ATOM   4235  N N   . PHE B 1 85  ? 1.814   -51.969 6.093   1.00 43.63  ? 85  PHE B N   1 
ATOM   4236  C CA  . PHE B 1 85  ? 1.674   -53.044 5.133   1.00 43.35  ? 85  PHE B CA  1 
ATOM   4237  C C   . PHE B 1 85  ? 1.491   -52.513 3.698   1.00 44.86  ? 85  PHE B C   1 
ATOM   4238  O O   . PHE B 1 85  ? 1.996   -53.093 2.734   1.00 43.29  ? 85  PHE B O   1 
ATOM   4239  C CB  . PHE B 1 85  ? 0.486   -53.913 5.551   1.00 44.35  ? 85  PHE B CB  1 
ATOM   4240  C CG  . PHE B 1 85  ? 0.347   -55.119 4.663   1.00 43.71  ? 85  PHE B CG  1 
ATOM   4241  C CD1 . PHE B 1 85  ? 1.238   -56.188 4.786   1.00 45.87  ? 85  PHE B CD1 1 
ATOM   4242  C CD2 . PHE B 1 85  ? -0.571  -55.130 3.622   1.00 48.54  ? 85  PHE B CD2 1 
ATOM   4243  C CE1 . PHE B 1 85  ? 1.165   -57.272 3.925   1.00 47.10  ? 85  PHE B CE1 1 
ATOM   4244  C CE2 . PHE B 1 85  ? -0.629  -56.215 2.753   1.00 45.13  ? 85  PHE B CE2 1 
ATOM   4245  C CZ  . PHE B 1 85  ? 0.230   -57.283 2.912   1.00 47.59  ? 85  PHE B CZ  1 
ATOM   4246  N N   . GLU B 1 86  ? 0.716   -51.427 3.532   1.00 43.54  ? 86  GLU B N   1 
ATOM   4247  C CA  . GLU B 1 86  ? 0.224   -51.032 2.221   1.00 38.04  ? 86  GLU B CA  1 
ATOM   4248  C C   . GLU B 1 86  ? 1.352   -50.411 1.421   1.00 37.30  ? 86  GLU B C   1 
ATOM   4249  O O   . GLU B 1 86  ? 2.229   -49.754 1.970   1.00 36.44  ? 86  GLU B O   1 
ATOM   4250  C CB  . GLU B 1 86  ? -0.981  -50.112 2.356   1.00 41.20  ? 86  GLU B CB  1 
ATOM   4251  C CG  . GLU B 1 86  ? -2.179  -50.811 2.973   1.00 40.97  ? 86  GLU B CG  1 
ATOM   4252  C CD  . GLU B 1 86  ? -2.640  -52.071 2.261   1.00 44.77  ? 86  GLU B CD  1 
ATOM   4253  O OE1 . GLU B 1 86  ? -3.421  -52.836 2.894   1.00 51.87  ? 86  GLU B OE1 1 
ATOM   4254  O OE2 . GLU B 1 86  ? -2.285  -52.260 1.050   1.00 41.11  ? 86  GLU B OE2 1 
ATOM   4255  N N   . PRO B 1 87  ? 1.394   -50.654 0.096   1.00 39.94  ? 87  PRO B N   1 
ATOM   4256  C CA  . PRO B 1 87  ? 2.461   -50.090 -0.729  1.00 38.66  ? 87  PRO B CA  1 
ATOM   4257  C C   . PRO B 1 87  ? 2.372   -48.556 -0.766  1.00 38.51  ? 87  PRO B C   1 
ATOM   4258  O O   . PRO B 1 87  ? 1.281   -47.981 -0.831  1.00 36.27  ? 87  PRO B O   1 
ATOM   4259  C CB  . PRO B 1 87  ? 2.227   -50.778 -2.083  1.00 41.18  ? 87  PRO B CB  1 
ATOM   4260  C CG  . PRO B 1 87  ? 0.724   -51.081 -2.102  1.00 40.68  ? 87  PRO B CG  1 
ATOM   4261  C CD  . PRO B 1 87  ? 0.373   -51.391 -0.666  1.00 37.27  ? 87  PRO B CD  1 
ATOM   4262  N N   . LEU B 1 88  ? 3.535   -47.890 -0.707  1.00 38.69  ? 88  LEU B N   1 
ATOM   4263  C CA  . LEU B 1 88  ? 3.574   -46.438 -0.829  1.00 38.99  ? 88  LEU B CA  1 
ATOM   4264  C C   . LEU B 1 88  ? 3.428   -46.024 -2.295  1.00 37.05  ? 88  LEU B C   1 
ATOM   4265  O O   . LEU B 1 88  ? 4.156   -46.507 -3.171  1.00 33.28  ? 88  LEU B O   1 
ATOM   4266  C CB  . LEU B 1 88  ? 4.876   -45.883 -0.253  1.00 38.12  ? 88  LEU B CB  1 
ATOM   4267  C CG  . LEU B 1 88  ? 5.004   -45.884 1.274   1.00 37.72  ? 88  LEU B CG  1 
ATOM   4268  C CD1 . LEU B 1 88  ? 6.241   -45.104 1.676   1.00 44.47  ? 88  LEU B CD1 1 
ATOM   4269  C CD2 . LEU B 1 88  ? 3.774   -45.316 1.961   1.00 40.29  ? 88  LEU B CD2 1 
ATOM   4270  N N   . PRO B 1 89  ? 2.489   -45.095 -2.606  1.00 35.81  ? 89  PRO B N   1 
ATOM   4271  C CA  . PRO B 1 89  ? 2.345   -44.596 -3.970  1.00 35.58  ? 89  PRO B CA  1 
ATOM   4272  C C   . PRO B 1 89  ? 3.663   -44.043 -4.512  1.00 34.62  ? 89  PRO B C   1 
ATOM   4273  O O   . PRO B 1 89  ? 3.934   -44.201 -5.694  1.00 37.08  ? 89  PRO B O   1 
ATOM   4274  C CB  . PRO B 1 89  ? 1.230   -43.540 -3.851  1.00 39.08  ? 89  PRO B CB  1 
ATOM   4275  C CG  . PRO B 1 89  ? 0.432   -43.957 -2.631  1.00 43.88  ? 89  PRO B CG  1 
ATOM   4276  C CD  . PRO B 1 89  ? 1.432   -44.608 -1.702  1.00 40.13  ? 89  PRO B CD  1 
ATOM   4277  N N   . GLU B 1 90  ? 4.535   -43.504 -3.649  1.00 31.65  ? 90  GLU B N   1 
ATOM   4278  C CA  . GLU B 1 90  ? 5.810   -42.956 -4.100  1.00 33.28  ? 90  GLU B CA  1 
ATOM   4279  C C   . GLU B 1 90  ? 6.607   -44.001 -4.887  1.00 35.59  ? 90  GLU B C   1 
ATOM   4280  O O   . GLU B 1 90  ? 7.286   -43.682 -5.871  1.00 35.29  ? 90  GLU B O   1 
ATOM   4281  C CB  . GLU B 1 90  ? 6.678   -42.499 -2.921  1.00 38.96  ? 90  GLU B CB  1 
ATOM   4282  C CG  . GLU B 1 90  ? 6.157   -41.293 -2.166  1.00 42.05  ? 90  GLU B CG  1 
ATOM   4283  C CD  . GLU B 1 90  ? 5.202   -41.502 -1.004  1.00 40.45  ? 90  GLU B CD  1 
ATOM   4284  O OE1 . GLU B 1 90  ? 5.337   -40.740 -0.016  1.00 41.09  ? 90  GLU B OE1 1 
ATOM   4285  O OE2 . GLU B 1 90  ? 4.293   -42.353 -1.100  1.00 33.62  ? 90  GLU B OE2 1 
ATOM   4286  N N   . GLY B 1 91  ? 6.590   -45.244 -4.404  1.00 37.52  ? 91  GLY B N   1 
ATOM   4287  C CA  . GLY B 1 91  ? 7.400   -46.296 -5.013  1.00 38.98  ? 91  GLY B CA  1 
ATOM   4288  C C   . GLY B 1 91  ? 6.779   -46.765 -6.326  1.00 38.81  ? 91  GLY B C   1 
ATOM   4289  O O   . GLY B 1 91  ? 7.512   -47.029 -7.287  1.00 37.63  ? 91  GLY B O   1 
ATOM   4290  N N   . LEU B 1 92  ? 5.439   -46.875 -6.325  1.00 35.06  ? 92  LEU B N   1 
ATOM   4291  C CA  . LEU B 1 92  ? 4.687   -47.147 -7.537  1.00 39.49  ? 92  LEU B CA  1 
ATOM   4292  C C   . LEU B 1 92  ? 4.998   -46.113 -8.627  1.00 40.25  ? 92  LEU B C   1 
ATOM   4293  O O   . LEU B 1 92  ? 5.125   -46.474 -9.788  1.00 35.89  ? 92  LEU B O   1 
ATOM   4294  C CB  . LEU B 1 92  ? 3.182   -47.170 -7.275  1.00 35.82  ? 92  LEU B CB  1 
ATOM   4295  C CG  . LEU B 1 92  ? 2.366   -47.418 -8.546  1.00 41.64  ? 92  LEU B CG  1 
ATOM   4296  C CD1 . LEU B 1 92  ? 2.672   -48.781 -9.134  1.00 40.31  ? 92  LEU B CD1 1 
ATOM   4297  C CD2 . LEU B 1 92  ? 0.887   -47.316 -8.295  1.00 45.10  ? 92  LEU B CD2 1 
ATOM   4298  N N   . TRP B 1 93  ? 5.129   -44.838 -8.248  1.00 35.34  ? 93  TRP B N   1 
ATOM   4299  C CA  . TRP B 1 93  ? 5.429   -43.786 -9.198  1.00 38.06  ? 93  TRP B CA  1 
ATOM   4300  C C   . TRP B 1 93  ? 6.813   -44.018 -9.818  1.00 39.35  ? 93  TRP B C   1 
ATOM   4301  O O   . TRP B 1 93  ? 6.971   -43.919 -11.038 1.00 37.49  ? 93  TRP B O   1 
ATOM   4302  C CB  . TRP B 1 93  ? 5.268   -42.421 -8.507  1.00 34.34  ? 93  TRP B CB  1 
ATOM   4303  C CG  . TRP B 1 93  ? 5.209   -41.279 -9.460  1.00 29.34  ? 93  TRP B CG  1 
ATOM   4304  C CD1 . TRP B 1 93  ? 4.267   -41.078 -10.420 1.00 30.11  ? 93  TRP B CD1 1 
ATOM   4305  C CD2 . TRP B 1 93  ? 6.129   -40.184 -9.564  1.00 29.84  ? 93  TRP B CD2 1 
ATOM   4306  N NE1 . TRP B 1 93  ? 4.533   -39.930 -11.107 1.00 30.61  ? 93  TRP B NE1 1 
ATOM   4307  C CE2 . TRP B 1 93  ? 5.671   -39.363 -10.607 1.00 30.11  ? 93  TRP B CE2 1 
ATOM   4308  C CE3 . TRP B 1 93  ? 7.286   -39.819 -8.883  1.00 30.27  ? 93  TRP B CE3 1 
ATOM   4309  C CZ2 . TRP B 1 93  ? 6.335   -38.205 -10.990 1.00 32.14  ? 93  TRP B CZ2 1 
ATOM   4310  C CZ3 . TRP B 1 93  ? 7.954   -38.687 -9.264  1.00 34.15  ? 93  TRP B CZ3 1 
ATOM   4311  C CH2 . TRP B 1 93  ? 7.487   -37.894 -10.309 1.00 39.09  ? 93  TRP B CH2 1 
ATOM   4312  N N   . TYR B 1 94  ? 7.797   -44.424 -8.996  1.00 37.38  ? 94  TYR B N   1 
ATOM   4313  C CA  . TYR B 1 94  ? 9.120   -44.818 -9.481  1.00 36.69  ? 94  TYR B CA  1 
ATOM   4314  C C   . TYR B 1 94  ? 8.962   -45.921 -10.544 1.00 37.52  ? 94  TYR B C   1 
ATOM   4315  O O   . TYR B 1 94  ? 9.566   -45.861 -11.611 1.00 35.72  ? 94  TYR B O   1 
ATOM   4316  C CB  . TYR B 1 94  ? 10.041  -45.244 -8.319  1.00 38.50  ? 94  TYR B CB  1 
ATOM   4317  C CG  . TYR B 1 94  ? 11.459  -45.579 -8.736  1.00 41.60  ? 94  TYR B CG  1 
ATOM   4318  C CD1 . TYR B 1 94  ? 11.777  -46.789 -9.360  1.00 42.33  ? 94  TYR B CD1 1 
ATOM   4319  C CD2 . TYR B 1 94  ? 12.497  -44.680 -8.519  1.00 44.62  ? 94  TYR B CD2 1 
ATOM   4320  C CE1 . TYR B 1 94  ? 13.074  -47.086 -9.774  1.00 35.53  ? 94  TYR B CE1 1 
ATOM   4321  C CE2 . TYR B 1 94  ? 13.800  -44.957 -8.916  1.00 43.84  ? 94  TYR B CE2 1 
ATOM   4322  C CZ  . TYR B 1 94  ? 14.085  -46.156 -9.557  1.00 44.93  ? 94  TYR B CZ  1 
ATOM   4323  O OH  . TYR B 1 94  ? 15.379  -46.365 -9.952  1.00 45.19  ? 94  TYR B OH  1 
ATOM   4324  N N   . LEU B 1 95  ? 8.108   -46.905 -10.266 1.00 30.40  ? 95  LEU B N   1 
ATOM   4325  C CA  . LEU B 1 95  ? 7.921   -48.030 -11.152 1.00 35.03  ? 95  LEU B CA  1 
ATOM   4326  C C   . LEU B 1 95  ? 7.281   -47.603 -12.474 1.00 38.92  ? 95  LEU B C   1 
ATOM   4327  O O   . LEU B 1 95  ? 7.718   -48.026 -13.555 1.00 35.62  ? 95  LEU B O   1 
ATOM   4328  C CB  . LEU B 1 95  ? 7.057   -49.069 -10.441 1.00 34.56  ? 95  LEU B CB  1 
ATOM   4329  C CG  . LEU B 1 95  ? 6.606   -50.240 -11.322 1.00 39.43  ? 95  LEU B CG  1 
ATOM   4330  C CD1 . LEU B 1 95  ? 7.810   -51.065 -11.822 1.00 37.32  ? 95  LEU B CD1 1 
ATOM   4331  C CD2 . LEU B 1 95  ? 5.615   -51.096 -10.572 1.00 39.25  ? 95  LEU B CD2 1 
ATOM   4332  N N   . LEU B 1 96  ? 6.217   -46.787 -12.394 1.00 40.09  ? 96  LEU B N   1 
ATOM   4333  C CA  . LEU B 1 96  ? 5.517   -46.350 -13.591 1.00 33.91  ? 96  LEU B CA  1 
ATOM   4334  C C   . LEU B 1 96  ? 6.471   -45.617 -14.519 1.00 34.67  ? 96  LEU B C   1 
ATOM   4335  O O   . LEU B 1 96  ? 6.405   -45.788 -15.739 1.00 32.46  ? 96  LEU B O   1 
ATOM   4336  C CB  . LEU B 1 96  ? 4.331   -45.454 -13.212 1.00 38.96  ? 96  LEU B CB  1 
ATOM   4337  C CG  . LEU B 1 96  ? 3.182   -46.114 -12.463 1.00 38.27  ? 96  LEU B CG  1 
ATOM   4338  C CD1 . LEU B 1 96  ? 2.019   -45.140 -12.313 1.00 44.61  ? 96  LEU B CD1 1 
ATOM   4339  C CD2 . LEU B 1 96  ? 2.701   -47.369 -13.141 1.00 44.24  ? 96  LEU B CD2 1 
ATOM   4340  N N   . LEU B 1 97  ? 7.319   -44.757 -13.951 1.00 30.77  ? 97  LEU B N   1 
ATOM   4341  C CA  . LEU B 1 97  ? 8.248   -44.000 -14.757 1.00 32.70  ? 97  LEU B CA  1 
ATOM   4342  C C   . LEU B 1 97  ? 9.353   -44.879 -15.372 1.00 38.25  ? 97  LEU B C   1 
ATOM   4343  O O   . LEU B 1 97  ? 9.656   -44.711 -16.560 1.00 36.19  ? 97  LEU B O   1 
ATOM   4344  C CB  . LEU B 1 97  ? 8.842   -42.886 -13.903 1.00 36.23  ? 97  LEU B CB  1 
ATOM   4345  C CG  . LEU B 1 97  ? 7.919   -41.680 -13.765 1.00 39.38  ? 97  LEU B CG  1 
ATOM   4346  C CD1 . LEU B 1 97  ? 8.379   -40.778 -12.630 1.00 40.00  ? 97  LEU B CD1 1 
ATOM   4347  C CD2 . LEU B 1 97  ? 7.868   -40.939 -15.075 1.00 42.00  ? 97  LEU B CD2 1 
ATOM   4348  N N   . THR B 1 98  ? 9.984   -45.764 -14.579 1.00 36.58  ? 98  THR B N   1 
ATOM   4349  C CA  . THR B 1 98  ? 11.221  -46.421 -15.010 1.00 35.81  ? 98  THR B CA  1 
ATOM   4350  C C   . THR B 1 98  ? 10.964  -47.806 -15.578 1.00 38.74  ? 98  THR B C   1 
ATOM   4351  O O   . THR B 1 98  ? 11.807  -48.357 -16.285 1.00 41.41  ? 98  THR B O   1 
ATOM   4352  C CB  . THR B 1 98  ? 12.224  -46.617 -13.873 1.00 39.01  ? 98  THR B CB  1 
ATOM   4353  O OG1 . THR B 1 98  ? 11.586  -47.410 -12.865 1.00 35.66  ? 98  THR B OG1 1 
ATOM   4354  C CG2 . THR B 1 98  ? 12.730  -45.290 -13.336 1.00 37.79  ? 98  THR B CG2 1 
ATOM   4355  N N   . GLY B 1 99  ? 9.846   -48.396 -15.181 1.00 36.43  ? 99  GLY B N   1 
ATOM   4356  C CA  . GLY B 1 99  ? 9.619   -49.791 -15.453 1.00 37.14  ? 99  GLY B CA  1 
ATOM   4357  C C   . GLY B 1 99  ? 10.438  -50.725 -14.567 1.00 39.88  ? 99  GLY B C   1 
ATOM   4358  O O   . GLY B 1 99  ? 10.366  -51.927 -14.790 1.00 44.07  ? 99  GLY B O   1 
ATOM   4359  N N   . GLU B 1 100 ? 11.137  -50.190 -13.549 1.00 42.50  ? 100 GLU B N   1 
ATOM   4360  C CA  . GLU B 1 100 ? 11.986  -50.955 -12.632 1.00 42.30  ? 100 GLU B CA  1 
ATOM   4361  C C   . GLU B 1 100 ? 11.468  -50.762 -11.209 1.00 42.87  ? 100 GLU B C   1 
ATOM   4362  O O   . GLU B 1 100 ? 10.933  -49.695 -10.898 1.00 42.98  ? 100 GLU B O   1 
ATOM   4363  C CB  . GLU B 1 100 ? 13.456  -50.492 -12.635 1.00 44.12  ? 100 GLU B CB  1 
ATOM   4364  C CG  . GLU B 1 100 ? 14.205  -50.735 -13.944 1.00 47.87  ? 100 GLU B CG  1 
ATOM   4365  C CD  . GLU B 1 100 ? 15.459  -49.884 -14.188 1.00 52.17  ? 100 GLU B CD  1 
ATOM   4366  O OE1 . GLU B 1 100 ? 16.100  -50.101 -15.231 1.00 50.72  ? 100 GLU B OE1 1 
ATOM   4367  O OE2 . GLU B 1 100 ? 15.804  -48.983 -13.361 1.00 52.45  ? 100 GLU B OE2 1 
ATOM   4368  N N   . LEU B 1 101 ? 11.658  -51.771 -10.346 1.00 40.39  ? 101 LEU B N   1 
ATOM   4369  C CA  . LEU B 1 101 ? 11.207  -51.685 -8.958  1.00 39.79  ? 101 LEU B CA  1 
ATOM   4370  C C   . LEU B 1 101 ? 12.156  -50.810 -8.151  1.00 42.43  ? 101 LEU B C   1 
ATOM   4371  O O   . LEU B 1 101 ? 13.369  -51.001 -8.204  1.00 33.33  ? 101 LEU B O   1 
ATOM   4372  C CB  . LEU B 1 101 ? 11.156  -53.071 -8.332  1.00 41.32  ? 101 LEU B CB  1 
ATOM   4373  C CG  . LEU B 1 101 ? 10.198  -54.042 -9.008  1.00 42.39  ? 101 LEU B CG  1 
ATOM   4374  C CD1 . LEU B 1 101 ? 10.482  -55.474 -8.569  1.00 43.94  ? 101 LEU B CD1 1 
ATOM   4375  C CD2 . LEU B 1 101 ? 8.763   -53.663 -8.700  1.00 38.00  ? 101 LEU B CD2 1 
ATOM   4376  N N   . PRO B 1 102 ? 11.630  -49.891 -7.304  1.00 42.35  ? 102 PRO B N   1 
ATOM   4377  C CA  . PRO B 1 102 ? 12.488  -49.060 -6.459  1.00 43.79  ? 102 PRO B CA  1 
ATOM   4378  C C   . PRO B 1 102 ? 13.064  -49.852 -5.279  1.00 39.62  ? 102 PRO B C   1 
ATOM   4379  O O   . PRO B 1 102 ? 12.461  -50.819 -4.814  1.00 34.60  ? 102 PRO B O   1 
ATOM   4380  C CB  . PRO B 1 102 ? 11.510  -47.976 -5.962  1.00 41.32  ? 102 PRO B CB  1 
ATOM   4381  C CG  . PRO B 1 102 ? 10.199  -48.750 -5.829  1.00 41.16  ? 102 PRO B CG  1 
ATOM   4382  C CD  . PRO B 1 102 ? 10.203  -49.728 -6.990  1.00 41.25  ? 102 PRO B CD  1 
ATOM   4383  N N   . THR B 1 103 ? 14.221  -49.383 -4.813  1.00 42.49  ? 103 THR B N   1 
ATOM   4384  C CA  . THR B 1 103 ? 14.809  -49.719 -3.521  1.00 43.45  ? 103 THR B CA  1 
ATOM   4385  C C   . THR B 1 103 ? 14.176  -48.848 -2.431  1.00 48.17  ? 103 THR B C   1 
ATOM   4386  O O   . THR B 1 103 ? 13.566  -47.805 -2.714  1.00 42.57  ? 103 THR B O   1 
ATOM   4387  C CB  . THR B 1 103 ? 16.325  -49.446 -3.554  1.00 49.31  ? 103 THR B CB  1 
ATOM   4388  O OG1 . THR B 1 103 ? 16.531  -48.050 -3.797  1.00 46.98  ? 103 THR B OG1 1 
ATOM   4389  C CG2 . THR B 1 103 ? 17.075  -50.231 -4.614  1.00 47.64  ? 103 THR B CG2 1 
ATOM   4390  N N   . GLU B 1 104 ? 14.372  -49.241 -1.169  1.00 43.77  ? 104 GLU B N   1 
ATOM   4391  C CA  . GLU B 1 104 ? 13.884  -48.461 -0.043  1.00 42.71  ? 104 GLU B CA  1 
ATOM   4392  C C   . GLU B 1 104 ? 14.426  -47.034 -0.155  1.00 45.07  ? 104 GLU B C   1 
ATOM   4393  O O   . GLU B 1 104 ? 13.659  -46.079 -0.044  1.00 43.31  ? 104 GLU B O   1 
ATOM   4394  C CB  . GLU B 1 104 ? 14.272  -49.132 1.276   1.00 51.26  ? 104 GLU B CB  1 
ATOM   4395  C CG  . GLU B 1 104 ? 13.570  -50.463 1.530   1.00 59.39  ? 104 GLU B CG  1 
ATOM   4396  C CD  . GLU B 1 104 ? 12.158  -50.382 2.092   1.00 63.20  ? 104 GLU B CD  1 
ATOM   4397  O OE1 . GLU B 1 104 ? 11.443  -51.425 2.099   1.00 66.89  ? 104 GLU B OE1 1 
ATOM   4398  O OE2 . GLU B 1 104 ? 11.772  -49.282 2.546   1.00 69.26  ? 104 GLU B OE2 1 
ATOM   4399  N N   . GLU B 1 105 ? 15.731  -46.887 -0.421  1.00 44.83  ? 105 GLU B N   1 
ATOM   4400  C CA  . GLU B 1 105 ? 16.353  -45.575 -0.592  1.00 49.95  ? 105 GLU B CA  1 
ATOM   4401  C C   . GLU B 1 105 ? 15.750  -44.781 -1.770  1.00 48.64  ? 105 GLU B C   1 
ATOM   4402  O O   . GLU B 1 105 ? 15.660  -43.541 -1.732  1.00 41.90  ? 105 GLU B O   1 
ATOM   4403  C CB  . GLU B 1 105 ? 17.862  -45.755 -0.787  1.00 60.24  ? 105 GLU B CB  1 
ATOM   4404  C CG  . GLU B 1 105 ? 18.653  -44.456 -0.757  1.00 75.53  ? 105 GLU B CG  1 
ATOM   4405  C CD  . GLU B 1 105 ? 19.871  -44.467 -1.668  1.00 95.45  ? 105 GLU B CD  1 
ATOM   4406  O OE1 . GLU B 1 105 ? 21.003  -44.496 -1.141  1.00 106.80 ? 105 GLU B OE1 1 
ATOM   4407  O OE2 . GLU B 1 105 ? 19.685  -44.438 -2.911  1.00 99.85  ? 105 GLU B OE2 1 
ATOM   4408  N N   . ASP B 1 106 ? 15.412  -45.460 -2.877  1.00 47.38  ? 106 ASP B N   1 
ATOM   4409  C CA  . ASP B 1 106 ? 14.739  -44.794 -3.988  1.00 47.22  ? 106 ASP B CA  1 
ATOM   4410  C C   . ASP B 1 106 ? 13.451  -44.117 -3.517  1.00 44.77  ? 106 ASP B C   1 
ATOM   4411  O O   . ASP B 1 106 ? 13.207  -42.945 -3.825  1.00 45.52  ? 106 ASP B O   1 
ATOM   4412  C CB  . ASP B 1 106 ? 14.393  -45.775 -5.111  1.00 53.15  ? 106 ASP B CB  1 
ATOM   4413  C CG  . ASP B 1 106 ? 15.613  -46.295 -5.859  1.00 55.80  ? 106 ASP B CG  1 
ATOM   4414  O OD1 . ASP B 1 106 ? 16.659  -45.616 -5.806  1.00 52.49  ? 106 ASP B OD1 1 
ATOM   4415  O OD2 . ASP B 1 106 ? 15.511  -47.394 -6.451  1.00 47.41  ? 106 ASP B OD2 1 
ATOM   4416  N N   . VAL B 1 107 ? 12.640  -44.871 -2.767  1.00 38.30  ? 107 VAL B N   1 
ATOM   4417  C CA  . VAL B 1 107 ? 11.361  -44.392 -2.271  1.00 42.78  ? 107 VAL B CA  1 
ATOM   4418  C C   . VAL B 1 107 ? 11.566  -43.212 -1.312  1.00 50.57  ? 107 VAL B C   1 
ATOM   4419  O O   . VAL B 1 107 ? 10.900  -42.175 -1.413  1.00 42.95  ? 107 VAL B O   1 
ATOM   4420  C CB  . VAL B 1 107 ? 10.609  -45.553 -1.604  1.00 42.97  ? 107 VAL B CB  1 
ATOM   4421  C CG1 . VAL B 1 107 ? 9.391   -45.082 -0.834  1.00 49.89  ? 107 VAL B CG1 1 
ATOM   4422  C CG2 . VAL B 1 107 ? 10.235  -46.576 -2.647  1.00 47.64  ? 107 VAL B CG2 1 
ATOM   4423  N N   . LYS B 1 108 ? 12.504  -43.370 -0.383  1.00 45.26  ? 108 LYS B N   1 
ATOM   4424  C CA  . LYS B 1 108 ? 12.792  -42.320 0.572   1.00 50.64  ? 108 LYS B CA  1 
ATOM   4425  C C   . LYS B 1 108 ? 13.218  -41.039 -0.142  1.00 47.36  ? 108 LYS B C   1 
ATOM   4426  O O   . LYS B 1 108 ? 12.890  -39.966 0.344   1.00 48.81  ? 108 LYS B O   1 
ATOM   4427  C CB  . LYS B 1 108 ? 13.864  -42.752 1.570   1.00 53.28  ? 108 LYS B CB  1 
ATOM   4428  C CG  . LYS B 1 108 ? 13.403  -43.802 2.575   1.00 64.73  ? 108 LYS B CG  1 
ATOM   4429  C CD  . LYS B 1 108 ? 14.285  -43.869 3.820   1.00 74.51  ? 108 LYS B CD  1 
ATOM   4430  C CE  . LYS B 1 108 ? 14.224  -45.206 4.533   1.00 79.72  ? 108 LYS B CE  1 
ATOM   4431  N NZ  . LYS B 1 108 ? 15.022  -46.248 3.837   1.00 84.22  ? 108 LYS B NZ  1 
ATOM   4432  N N   . GLU B 1 109 ? 13.970  -41.120 -1.245  1.00 42.55  ? 109 GLU B N   1 
ATOM   4433  C CA  . GLU B 1 109 ? 14.361  -39.895 -1.939  1.00 48.27  ? 109 GLU B CA  1 
ATOM   4434  C C   . GLU B 1 109 ? 13.123  -39.186 -2.501  1.00 48.55  ? 109 GLU B C   1 
ATOM   4435  O O   . GLU B 1 109 ? 13.093  -37.961 -2.543  1.00 41.56  ? 109 GLU B O   1 
ATOM   4436  C CB  . GLU B 1 109 ? 15.303  -40.146 -3.118  1.00 56.66  ? 109 GLU B CB  1 
ATOM   4437  C CG  . GLU B 1 109 ? 16.751  -40.413 -2.746  1.00 63.78  ? 109 GLU B CG  1 
ATOM   4438  C CD  . GLU B 1 109 ? 17.584  -40.981 -3.893  1.00 71.51  ? 109 GLU B CD  1 
ATOM   4439  O OE1 . GLU B 1 109 ? 18.737  -41.374 -3.626  1.00 61.89  ? 109 GLU B OE1 1 
ATOM   4440  O OE2 . GLU B 1 109 ? 17.076  -41.046 -5.060  1.00 69.75  ? 109 GLU B OE2 1 
ATOM   4441  N N   . ILE B 1 110 ? 12.127  -39.964 -2.963  1.00 43.10  ? 110 ILE B N   1 
ATOM   4442  C CA  . ILE B 1 110 ? 10.936  -39.442 -3.608  1.00 45.73  ? 110 ILE B CA  1 
ATOM   4443  C C   . ILE B 1 110 ? 10.048  -38.812 -2.543  1.00 48.79  ? 110 ILE B C   1 
ATOM   4444  O O   . ILE B 1 110 ? 9.496   -37.738 -2.787  1.00 45.48  ? 110 ILE B O   1 
ATOM   4445  C CB  . ILE B 1 110 ? 10.183  -40.529 -4.404  1.00 42.14  ? 110 ILE B CB  1 
ATOM   4446  C CG1 . ILE B 1 110 ? 10.973  -40.974 -5.637  1.00 46.63  ? 110 ILE B CG1 1 
ATOM   4447  C CG2 . ILE B 1 110 ? 8.787   -40.072 -4.796  1.00 44.96  ? 110 ILE B CG2 1 
ATOM   4448  C CD1 . ILE B 1 110 ? 10.411  -42.217 -6.268  1.00 43.94  ? 110 ILE B CD1 1 
ATOM   4449  N N   . SER B 1 111 ? 9.909   -39.513 -1.407  1.00 47.30  ? 111 SER B N   1 
ATOM   4450  C CA  . SER B 1 111 ? 9.197   -39.016 -0.238  1.00 47.99  ? 111 SER B CA  1 
ATOM   4451  C C   . SER B 1 111 ? 9.773   -37.686 0.253   1.00 46.84  ? 111 SER B C   1 
ATOM   4452  O O   . SER B 1 111 ? 9.013   -36.767 0.545   1.00 48.97  ? 111 SER B O   1 
ATOM   4453  C CB  . SER B 1 111 ? 9.131   -40.054 0.862   1.00 44.87  ? 111 SER B CB  1 
ATOM   4454  O OG  . SER B 1 111 ? 8.083   -40.996 0.581   1.00 44.82  ? 111 SER B OG  1 
ATOM   4455  N N   . ALA B 1 112 ? 11.098  -37.559 0.300   1.00 45.24  ? 112 ALA B N   1 
ATOM   4456  C CA  . ALA B 1 112 ? 11.719  -36.330 0.765   1.00 51.31  ? 112 ALA B CA  1 
ATOM   4457  C C   . ALA B 1 112 ? 11.494  -35.205 -0.244  1.00 53.69  ? 112 ALA B C   1 
ATOM   4458  O O   . ALA B 1 112 ? 11.523  -34.038 0.110   1.00 45.95  ? 112 ALA B O   1 
ATOM   4459  C CB  . ALA B 1 112 ? 13.207  -36.518 0.970   1.00 46.70  ? 112 ALA B CB  1 
ATOM   4460  N N   . GLU B 1 113 ? 11.413  -35.560 -1.528  1.00 47.90  ? 113 GLU B N   1 
ATOM   4461  C CA  . GLU B 1 113 ? 11.227  -34.572 -2.568  1.00 46.73  ? 113 GLU B CA  1 
ATOM   4462  C C   . GLU B 1 113 ? 9.809   -34.003 -2.400  1.00 43.72  ? 113 GLU B C   1 
ATOM   4463  O O   . GLU B 1 113 ? 9.598   -32.790 -2.485  1.00 44.42  ? 113 GLU B O   1 
ATOM   4464  C CB  . GLU B 1 113 ? 11.542  -35.299 -3.876  1.00 54.07  ? 113 GLU B CB  1 
ATOM   4465  C CG  . GLU B 1 113 ? 12.048  -34.416 -4.977  1.00 66.04  ? 113 GLU B CG  1 
ATOM   4466  C CD  . GLU B 1 113 ? 13.379  -33.734 -4.725  1.00 72.38  ? 113 GLU B CD  1 
ATOM   4467  O OE1 . GLU B 1 113 ? 13.344  -32.529 -4.426  1.00 64.62  ? 113 GLU B OE1 1 
ATOM   4468  O OE2 . GLU B 1 113 ? 14.438  -34.392 -4.889  1.00 71.93  ? 113 GLU B OE2 1 
ATOM   4469  N N   . PHE B 1 114 ? 8.865   -34.900 -2.080  1.00 38.03  ? 114 PHE B N   1 
ATOM   4470  C CA  . PHE B 1 114 ? 7.463   -34.577 -1.948  1.00 44.04  ? 114 PHE B CA  1 
ATOM   4471  C C   . PHE B 1 114 ? 7.242   -33.748 -0.690  1.00 49.68  ? 114 PHE B C   1 
ATOM   4472  O O   . PHE B 1 114 ? 6.455   -32.805 -0.721  1.00 45.78  ? 114 PHE B O   1 
ATOM   4473  C CB  . PHE B 1 114 ? 6.588   -35.839 -1.951  1.00 36.69  ? 114 PHE B CB  1 
ATOM   4474  C CG  . PHE B 1 114 ? 6.309   -36.452 -3.307  1.00 40.88  ? 114 PHE B CG  1 
ATOM   4475  C CD1 . PHE B 1 114 ? 6.679   -35.831 -4.496  1.00 39.77  ? 114 PHE B CD1 1 
ATOM   4476  C CD2 . PHE B 1 114 ? 5.631   -37.660 -3.403  1.00 39.57  ? 114 PHE B CD2 1 
ATOM   4477  C CE1 . PHE B 1 114 ? 6.407   -36.429 -5.724  1.00 39.99  ? 114 PHE B CE1 1 
ATOM   4478  C CE2 . PHE B 1 114 ? 5.370   -38.256 -4.631  1.00 41.17  ? 114 PHE B CE2 1 
ATOM   4479  C CZ  . PHE B 1 114 ? 5.797   -37.663 -5.792  1.00 38.82  ? 114 PHE B CZ  1 
ATOM   4480  N N   . THR B 1 115 ? 7.914   -34.125 0.401   1.00 54.05  ? 115 THR B N   1 
ATOM   4481  C CA  . THR B 1 115 ? 7.768   -33.461 1.689   1.00 53.69  ? 115 THR B CA  1 
ATOM   4482  C C   . THR B 1 115 ? 8.311   -32.037 1.601   1.00 53.43  ? 115 THR B C   1 
ATOM   4483  O O   . THR B 1 115 ? 7.658   -31.095 2.029   1.00 63.02  ? 115 THR B O   1 
ATOM   4484  C CB  . THR B 1 115 ? 8.414   -34.293 2.812   1.00 63.53  ? 115 THR B CB  1 
ATOM   4485  O OG1 . THR B 1 115 ? 7.473   -35.292 3.202   1.00 54.63  ? 115 THR B OG1 1 
ATOM   4486  C CG2 . THR B 1 115 ? 8.774   -33.495 4.046   1.00 64.92  ? 115 THR B CG2 1 
ATOM   4487  N N   . LYS B 1 116 ? 9.487   -31.883 1.008   1.00 46.17  ? 116 LYS B N   1 
ATOM   4488  C CA  . LYS B 1 116 ? 10.075  -30.579 0.800   1.00 47.12  ? 116 LYS B CA  1 
ATOM   4489  C C   . LYS B 1 116 ? 9.149   -29.691 -0.037  1.00 45.80  ? 116 LYS B C   1 
ATOM   4490  O O   . LYS B 1 116 ? 8.965   -28.514 0.258   1.00 41.25  ? 116 LYS B O   1 
ATOM   4491  C CB  . LYS B 1 116 ? 11.423  -30.735 0.101   1.00 47.81  ? 116 LYS B CB  1 
ATOM   4492  C CG  . LYS B 1 116 ? 12.171  -29.429 -0.123  1.00 62.55  ? 116 LYS B CG  1 
ATOM   4493  C CD  . LYS B 1 116 ? 13.481  -29.571 -0.870  1.00 71.04  ? 116 LYS B CD  1 
ATOM   4494  C CE  . LYS B 1 116 ? 13.995  -28.226 -1.337  1.00 84.45  ? 116 LYS B CE  1 
ATOM   4495  N NZ  . LYS B 1 116 ? 15.048  -28.365 -2.370  1.00 92.99  ? 116 LYS B NZ  1 
ATOM   4496  N N   . ARG B 1 117 ? 8.592   -30.249 -1.115  1.00 36.35  ? 117 ARG B N   1 
ATOM   4497  C CA  . ARG B 1 117 ? 7.958   -29.445 -2.138  1.00 34.91  ? 117 ARG B CA  1 
ATOM   4498  C C   . ARG B 1 117 ? 6.552   -29.056 -1.666  1.00 30.98  ? 117 ARG B C   1 
ATOM   4499  O O   . ARG B 1 117 ? 5.966   -28.084 -2.142  1.00 30.50  ? 117 ARG B O   1 
ATOM   4500  C CB  . ARG B 1 117 ? 8.038   -30.209 -3.465  1.00 35.88  ? 117 ARG B CB  1 
ATOM   4501  C CG  . ARG B 1 117 ? 9.423   -30.201 -4.094  1.00 36.97  ? 117 ARG B CG  1 
ATOM   4502  C CD  . ARG B 1 117 ? 9.577   -31.164 -5.267  1.00 42.20  ? 117 ARG B CD  1 
ATOM   4503  N NE  . ARG B 1 117 ? 10.971  -31.262 -5.692  1.00 32.86  ? 117 ARG B NE  1 
ATOM   4504  C CZ  . ARG B 1 117 ? 11.530  -30.624 -6.724  1.00 41.68  ? 117 ARG B CZ  1 
ATOM   4505  N NH1 . ARG B 1 117 ? 10.835  -29.796 -7.493  1.00 38.14  ? 117 ARG B NH1 1 
ATOM   4506  N NH2 . ARG B 1 117 ? 12.816  -30.817 -6.984  1.00 43.02  ? 117 ARG B NH2 1 
ATOM   4507  N N   . MET B 1 118 ? 6.028   -29.843 -0.736  1.00 30.14  ? 118 MET B N   1 
ATOM   4508  C CA  . MET B 1 118 ? 4.697   -29.692 -0.200  1.00 32.96  ? 118 MET B CA  1 
ATOM   4509  C C   . MET B 1 118 ? 4.608   -28.428 0.661   1.00 33.73  ? 118 MET B C   1 
ATOM   4510  O O   . MET B 1 118 ? 3.524   -27.936 0.928   1.00 33.98  ? 118 MET B O   1 
ATOM   4511  C CB  . MET B 1 118 ? 4.385   -30.922 0.638   1.00 35.56  ? 118 MET B CB  1 
ATOM   4512  C CG  . MET B 1 118 ? 2.971   -31.070 0.989   1.00 36.74  ? 118 MET B CG  1 
ATOM   4513  S SD  . MET B 1 118 ? 2.568   -32.635 1.844   1.00 39.43  ? 118 MET B SD  1 
ATOM   4514  C CE  . MET B 1 118 ? 2.749   -33.822 0.511   1.00 42.26  ? 118 MET B CE  1 
ATOM   4515  N N   . GLN B 1 119 ? 5.756   -27.851 0.977   1.00 33.82  ? 119 GLN B N   1 
ATOM   4516  C CA  . GLN B 1 119 ? 5.893   -26.572 1.657   1.00 35.63  ? 119 GLN B CA  1 
ATOM   4517  C C   . GLN B 1 119 ? 5.997   -25.415 0.688   1.00 33.72  ? 119 GLN B C   1 
ATOM   4518  O O   . GLN B 1 119 ? 6.174   -24.273 1.090   1.00 35.02  ? 119 GLN B O   1 
ATOM   4519  C CB  . GLN B 1 119 ? 7.244   -26.565 2.380   1.00 40.49  ? 119 GLN B CB  1 
ATOM   4520  C CG  . GLN B 1 119 ? 7.354   -27.608 3.467   1.00 38.99  ? 119 GLN B CG  1 
ATOM   4521  C CD  . GLN B 1 119 ? 6.507   -27.241 4.654   1.00 51.01  ? 119 GLN B CD  1 
ATOM   4522  O OE1 . GLN B 1 119 ? 6.455   -26.075 5.047   1.00 54.36  ? 119 GLN B OE1 1 
ATOM   4523  N NE2 . GLN B 1 119 ? 5.817   -28.223 5.223   1.00 55.78  ? 119 GLN B NE2 1 
ATOM   4524  N N   . ASN B 1 120 ? 5.963   -25.702 -0.602  1.00 30.27  ? 120 ASN B N   1 
ATOM   4525  C CA  . ASN B 1 120 ? 6.196   -24.668 -1.586  1.00 33.68  ? 120 ASN B CA  1 
ATOM   4526  C C   . ASN B 1 120 ? 4.936   -24.344 -2.390  1.00 27.52  ? 120 ASN B C   1 
ATOM   4527  O O   . ASN B 1 120 ? 5.042   -23.947 -3.544  1.00 30.69  ? 120 ASN B O   1 
ATOM   4528  C CB  . ASN B 1 120 ? 7.312   -25.084 -2.557  1.00 38.89  ? 120 ASN B CB  1 
ATOM   4529  C CG  . ASN B 1 120 ? 8.634   -25.336 -1.864  1.00 45.97  ? 120 ASN B CG  1 
ATOM   4530  O OD1 . ASN B 1 120 ? 8.898   -24.813 -0.782  1.00 47.54  ? 120 ASN B OD1 1 
ATOM   4531  N ND2 . ASN B 1 120 ? 9.482   -26.120 -2.505  1.00 46.35  ? 120 ASN B ND2 1 
ATOM   4532  N N   . VAL B 1 121 ? 3.740   -24.533 -1.833  1.00 25.45  ? 121 VAL B N   1 
ATOM   4533  C CA  . VAL B 1 121 ? 2.557   -24.121 -2.565  1.00 25.84  ? 121 VAL B CA  1 
ATOM   4534  C C   . VAL B 1 121 ? 2.431   -22.607 -2.453  1.00 26.29  ? 121 VAL B C   1 
ATOM   4535  O O   . VAL B 1 121 ? 2.438   -22.066 -1.348  1.00 25.40  ? 121 VAL B O   1 
ATOM   4536  C CB  . VAL B 1 121 ? 1.290   -24.829 -2.081  1.00 25.63  ? 121 VAL B CB  1 
ATOM   4537  C CG1 . VAL B 1 121 ? 0.107   -24.410 -2.944  1.00 28.80  ? 121 VAL B CG1 1 
ATOM   4538  C CG2 . VAL B 1 121 ? 1.488   -26.322 -2.108  1.00 29.85  ? 121 VAL B CG2 1 
ATOM   4539  N N   . PRO B 1 122 ? 2.409   -21.863 -3.571  1.00 26.88  ? 122 PRO B N   1 
ATOM   4540  C CA  . PRO B 1 122 ? 2.324   -20.407 -3.517  1.00 26.48  ? 122 PRO B CA  1 
ATOM   4541  C C   . PRO B 1 122 ? 1.121   -19.884 -2.764  1.00 28.73  ? 122 PRO B C   1 
ATOM   4542  O O   . PRO B 1 122 ? 0.012   -20.431 -2.876  1.00 24.83  ? 122 PRO B O   1 
ATOM   4543  C CB  . PRO B 1 122 ? 2.150   -20.003 -4.989  1.00 25.95  ? 122 PRO B CB  1 
ATOM   4544  C CG  . PRO B 1 122 ? 2.859   -21.105 -5.721  1.00 26.90  ? 122 PRO B CG  1 
ATOM   4545  C CD  . PRO B 1 122 ? 2.570   -22.357 -4.947  1.00 27.72  ? 122 PRO B CD  1 
ATOM   4546  N N   . GLN B 1 123 ? 1.347   -18.813 -2.005  1.00 26.56  ? 123 GLN B N   1 
ATOM   4547  C CA  . GLN B 1 123 ? 0.275   -18.224 -1.226  1.00 26.02  ? 123 GLN B CA  1 
ATOM   4548  C C   . GLN B 1 123 ? -0.878  -17.785 -2.138  1.00 21.49  ? 123 GLN B C   1 
ATOM   4549  O O   . GLN B 1 123 ? -2.006  -17.843 -1.713  1.00 21.53  ? 123 GLN B O   1 
ATOM   4550  C CB  . GLN B 1 123 ? 0.858   -17.095 -0.385  1.00 29.02  ? 123 GLN B CB  1 
ATOM   4551  C CG  . GLN B 1 123 ? -0.159  -16.212 0.307   1.00 36.22  ? 123 GLN B CG  1 
ATOM   4552  C CD  . GLN B 1 123 ? -0.931  -16.965 1.359   1.00 41.85  ? 123 GLN B CD  1 
ATOM   4553  O OE1 . GLN B 1 123 ? -0.358  -17.590 2.241   1.00 46.45  ? 123 GLN B OE1 1 
ATOM   4554  N NE2 . GLN B 1 123 ? -2.251  -16.926 1.259   1.00 47.40  ? 123 GLN B NE2 1 
ATOM   4555  N N   . TYR B 1 124 ? -0.605  -17.327 -3.362  1.00 21.72  ? 124 TYR B N   1 
ATOM   4556  C CA  . TYR B 1 124 ? -1.631  -16.874 -4.282  1.00 24.03  ? 124 TYR B CA  1 
ATOM   4557  C C   . TYR B 1 124 ? -2.542  -18.028 -4.697  1.00 24.55  ? 124 TYR B C   1 
ATOM   4558  O O   . TYR B 1 124 ? -3.644  -17.777 -5.117  1.00 23.45  ? 124 TYR B O   1 
ATOM   4559  C CB  . TYR B 1 124 ? -1.063  -16.142 -5.502  1.00 24.05  ? 124 TYR B CB  1 
ATOM   4560  C CG  . TYR B 1 124 ? -0.239  -16.987 -6.435  1.00 26.90  ? 124 TYR B CG  1 
ATOM   4561  C CD1 . TYR B 1 124 ? -0.850  -17.881 -7.293  1.00 27.61  ? 124 TYR B CD1 1 
ATOM   4562  C CD2 . TYR B 1 124 ? 1.156   -16.936 -6.427  1.00 26.50  ? 124 TYR B CD2 1 
ATOM   4563  C CE1 . TYR B 1 124 ? -0.106  -18.700 -8.114  1.00 26.79  ? 124 TYR B CE1 1 
ATOM   4564  C CE2 . TYR B 1 124 ? 1.905   -17.740 -7.264  1.00 27.82  ? 124 TYR B CE2 1 
ATOM   4565  C CZ  . TYR B 1 124 ? 1.264   -18.639 -8.103  1.00 28.59  ? 124 TYR B CZ  1 
ATOM   4566  O OH  . TYR B 1 124 ? 1.936   -19.505 -8.940  1.00 32.36  ? 124 TYR B OH  1 
ATOM   4567  N N   . VAL B 1 125 ? -2.108  -19.277 -4.586  1.00 27.15  ? 125 VAL B N   1 
ATOM   4568  C CA  . VAL B 1 125 ? -2.987  -20.394 -4.897  1.00 25.28  ? 125 VAL B CA  1 
ATOM   4569  C C   . VAL B 1 125 ? -4.128  -20.419 -3.897  1.00 25.10  ? 125 VAL B C   1 
ATOM   4570  O O   . VAL B 1 125 ? -5.290  -20.641 -4.253  1.00 25.34  ? 125 VAL B O   1 
ATOM   4571  C CB  . VAL B 1 125 ? -2.252  -21.738 -4.898  1.00 27.25  ? 125 VAL B CB  1 
ATOM   4572  C CG1 . VAL B 1 125 ? -3.212  -22.923 -4.873  1.00 30.71  ? 125 VAL B CG1 1 
ATOM   4573  C CG2 . VAL B 1 125 ? -1.320  -21.833 -6.074  1.00 27.93  ? 125 VAL B CG2 1 
ATOM   4574  N N   . PHE B 1 126 ? -3.799  -20.197 -2.635  1.00 28.43  ? 126 PHE B N   1 
ATOM   4575  C CA  . PHE B 1 126 ? -4.828  -20.129 -1.614  1.00 25.32  ? 126 PHE B CA  1 
ATOM   4576  C C   . PHE B 1 126 ? -5.694  -18.880 -1.768  1.00 28.29  ? 126 PHE B C   1 
ATOM   4577  O O   . PHE B 1 126 ? -6.858  -18.944 -1.421  1.00 27.00  ? 126 PHE B O   1 
ATOM   4578  C CB  . PHE B 1 126 ? -4.221  -20.171 -0.214  1.00 24.83  ? 126 PHE B CB  1 
ATOM   4579  C CG  . PHE B 1 126 ? -3.396  -21.409 -0.020  1.00 27.12  ? 126 PHE B CG  1 
ATOM   4580  C CD1 . PHE B 1 126 ? -4.002  -22.645 0.163   1.00 31.35  ? 126 PHE B CD1 1 
ATOM   4581  C CD2 . PHE B 1 126 ? -2.013  -21.344 -0.076  1.00 27.41  ? 126 PHE B CD2 1 
ATOM   4582  C CE1 . PHE B 1 126 ? -3.234  -23.791 0.321   1.00 32.75  ? 126 PHE B CE1 1 
ATOM   4583  C CE2 . PHE B 1 126 ? -1.246  -22.478 0.108   1.00 33.58  ? 126 PHE B CE2 1 
ATOM   4584  C CZ  . PHE B 1 126 ? -1.856  -23.702 0.306   1.00 34.57  ? 126 PHE B CZ  1 
ATOM   4585  N N   . ASP B 1 127 ? -5.130  -17.757 -2.215  1.00 25.54  ? 127 ASP B N   1 
ATOM   4586  C CA  . ASP B 1 127 ? -5.944  -16.580 -2.505  1.00 27.18  ? 127 ASP B CA  1 
ATOM   4587  C C   . ASP B 1 127 ? -6.969  -16.938 -3.583  1.00 26.45  ? 127 ASP B C   1 
ATOM   4588  O O   . ASP B 1 127 ? -8.100  -16.490 -3.541  1.00 24.79  ? 127 ASP B O   1 
ATOM   4589  C CB  . ASP B 1 127 ? -5.119  -15.387 -2.992  1.00 26.79  ? 127 ASP B CB  1 
ATOM   4590  C CG  . ASP B 1 127 ? -4.083  -14.868 -1.987  1.00 29.73  ? 127 ASP B CG  1 
ATOM   4591  O OD1 . ASP B 1 127 ? -4.158  -15.253 -0.805  1.00 32.95  ? 127 ASP B OD1 1 
ATOM   4592  O OD2 . ASP B 1 127 ? -3.177  -14.125 -2.404  1.00 30.78  ? 127 ASP B OD2 1 
ATOM   4593  N N   . VAL B 1 128 ? -6.542  -17.657 -4.609  1.00 22.87  ? 128 VAL B N   1 
ATOM   4594  C CA  . VAL B 1 128 ? -7.444  -18.026 -5.685  1.00 22.75  ? 128 VAL B CA  1 
ATOM   4595  C C   . VAL B 1 128 ? -8.557  -18.887 -5.124  1.00 24.76  ? 128 VAL B C   1 
ATOM   4596  O O   . VAL B 1 128 ? -9.728  -18.609 -5.380  1.00 25.86  ? 128 VAL B O   1 
ATOM   4597  C CB  . VAL B 1 128 ? -6.703  -18.735 -6.838  1.00 24.06  ? 128 VAL B CB  1 
ATOM   4598  C CG1 . VAL B 1 128 ? -7.637  -19.460 -7.768  1.00 28.33  ? 128 VAL B CG1 1 
ATOM   4599  C CG2 . VAL B 1 128 ? -5.862  -17.756 -7.651  1.00 24.04  ? 128 VAL B CG2 1 
ATOM   4600  N N   . LEU B 1 129 ? -8.181  -19.898 -4.341  1.00 27.57  ? 129 LEU B N   1 
ATOM   4601  C CA  . LEU B 1 129 ? -9.133  -20.827 -3.770  1.00 28.14  ? 129 LEU B CA  1 
ATOM   4602  C C   . LEU B 1 129 ? -10.130 -20.061 -2.915  1.00 29.22  ? 129 LEU B C   1 
ATOM   4603  O O   . LEU B 1 129 ? -11.339 -20.324 -3.003  1.00 29.22  ? 129 LEU B O   1 
ATOM   4604  C CB  . LEU B 1 129 ? -8.407  -21.905 -2.956  1.00 28.37  ? 129 LEU B CB  1 
ATOM   4605  C CG  . LEU B 1 129 ? -7.686  -22.979 -3.765  1.00 31.16  ? 129 LEU B CG  1 
ATOM   4606  C CD1 . LEU B 1 129 ? -6.819  -23.821 -2.857  1.00 28.46  ? 129 LEU B CD1 1 
ATOM   4607  C CD2 . LEU B 1 129 ? -8.692  -23.858 -4.494  1.00 32.39  ? 129 LEU B CD2 1 
ATOM   4608  N N   . ARG B 1 130 ? -9.656  -19.090 -2.122  1.00 27.61  ? 130 ARG B N   1 
ATOM   4609  C CA  . ARG B 1 130 ? -10.563 -18.400 -1.210  1.00 26.15  ? 130 ARG B CA  1 
ATOM   4610  C C   . ARG B 1 130 ? -11.448 -17.413 -1.968  1.00 25.00  ? 130 ARG B C   1 
ATOM   4611  O O   . ARG B 1 130 ? -12.513 -17.090 -1.508  1.00 26.49  ? 130 ARG B O   1 
ATOM   4612  C CB  . ARG B 1 130 ? -9.875  -17.610 -0.092  1.00 32.05  ? 130 ARG B CB  1 
ATOM   4613  C CG  . ARG B 1 130 ? -9.374  -18.419 1.090   1.00 38.33  ? 130 ARG B CG  1 
ATOM   4614  C CD  . ARG B 1 130 ? -8.899  -17.531 2.246   1.00 34.03  ? 130 ARG B CD  1 
ATOM   4615  N NE  . ARG B 1 130 ? -9.969  -17.221 3.177   1.00 31.63  ? 130 ARG B NE  1 
ATOM   4616  C CZ  . ARG B 1 130 ? -10.592 -18.121 3.934   1.00 33.64  ? 130 ARG B CZ  1 
ATOM   4617  N NH1 . ARG B 1 130 ? -11.532 -17.750 4.787   1.00 33.99  ? 130 ARG B NH1 1 
ATOM   4618  N NH2 . ARG B 1 130 ? -10.254 -19.395 3.864   1.00 33.45  ? 130 ARG B NH2 1 
ATOM   4619  N N   . ALA B 1 131 ? -11.072 -16.972 -3.161  1.00 25.53  ? 131 ALA B N   1 
ATOM   4620  C CA  . ALA B 1 131 ? -11.921 -16.037 -3.907  1.00 25.97  ? 131 ALA B CA  1 
ATOM   4621  C C   . ALA B 1 131 ? -13.120 -16.763 -4.540  1.00 26.68  ? 131 ALA B C   1 
ATOM   4622  O O   . ALA B 1 131 ? -14.095 -16.147 -4.961  1.00 24.33  ? 131 ALA B O   1 
ATOM   4623  C CB  . ALA B 1 131 ? -11.066 -15.384 -4.977  1.00 26.34  ? 131 ALA B CB  1 
ATOM   4624  N N   . MET B 1 132 ? -13.017 -18.082 -4.690  1.00 25.72  ? 132 MET B N   1 
ATOM   4625  C CA  . MET B 1 132 ? -14.137 -18.863 -5.190  1.00 27.77  ? 132 MET B CA  1 
ATOM   4626  C C   . MET B 1 132 ? -15.179 -19.004 -4.091  1.00 25.97  ? 132 MET B C   1 
ATOM   4627  O O   . MET B 1 132 ? -14.842 -19.281 -2.944  1.00 25.92  ? 132 MET B O   1 
ATOM   4628  C CB  . MET B 1 132 ? -13.673 -20.249 -5.603  1.00 26.54  ? 132 MET B CB  1 
ATOM   4629  C CG  . MET B 1 132 ? -12.767 -20.143 -6.784  1.00 32.17  ? 132 MET B CG  1 
ATOM   4630  S SD  . MET B 1 132 ? -12.049 -21.739 -7.215  1.00 34.90  ? 132 MET B SD  1 
ATOM   4631  C CE  . MET B 1 132 ? -13.042 -22.057 -8.659  1.00 33.81  ? 132 MET B CE  1 
ATOM   4632  N N   . PRO B 1 133 ? -16.473 -18.846 -4.412  1.00 26.76  ? 133 PRO B N   1 
ATOM   4633  C CA  . PRO B 1 133 ? -17.522 -19.032 -3.413  1.00 27.08  ? 133 PRO B CA  1 
ATOM   4634  C C   . PRO B 1 133 ? -17.467 -20.441 -2.843  1.00 26.62  ? 133 PRO B C   1 
ATOM   4635  O O   . PRO B 1 133 ? -17.206 -21.392 -3.567  1.00 28.10  ? 133 PRO B O   1 
ATOM   4636  C CB  . PRO B 1 133 ? -18.822 -18.783 -4.183  1.00 29.85  ? 133 PRO B CB  1 
ATOM   4637  C CG  . PRO B 1 133 ? -18.396 -17.985 -5.401  1.00 28.92  ? 133 PRO B CG  1 
ATOM   4638  C CD  . PRO B 1 133 ? -16.988 -18.439 -5.735  1.00 26.04  ? 133 PRO B CD  1 
ATOM   4639  N N   . VAL B 1 134 ? -17.695 -20.546 -1.536  1.00 25.65  ? 134 VAL B N   1 
ATOM   4640  C CA  . VAL B 1 134 ? -17.429 -21.773 -0.825  1.00 24.02  ? 134 VAL B CA  1 
ATOM   4641  C C   . VAL B 1 134 ? -18.369 -22.895 -1.301  1.00 27.17  ? 134 VAL B C   1 
ATOM   4642  O O   . VAL B 1 134 ? -18.034 -24.069 -1.148  1.00 26.41  ? 134 VAL B O   1 
ATOM   4643  C CB  . VAL B 1 134 ? -17.483 -21.520 0.680   1.00 26.82  ? 134 VAL B CB  1 
ATOM   4644  C CG1 . VAL B 1 134 ? -18.907 -21.262 1.179   1.00 25.81  ? 134 VAL B CG1 1 
ATOM   4645  C CG2 . VAL B 1 134 ? -16.799 -22.669 1.449   1.00 27.08  ? 134 VAL B CG2 1 
ATOM   4646  N N   . ASP B 1 135 ? -19.519 -22.547 -1.906  1.00 25.95  ? 135 ASP B N   1 
ATOM   4647  C CA  . ASP B 1 135 ? -20.472 -23.536 -2.400  1.00 27.46  ? 135 ASP B CA  1 
ATOM   4648  C C   . ASP B 1 135 ? -20.091 -24.016 -3.807  1.00 29.12  ? 135 ASP B C   1 
ATOM   4649  O O   . ASP B 1 135 ? -20.801 -24.815 -4.396  1.00 28.95  ? 135 ASP B O   1 
ATOM   4650  C CB  . ASP B 1 135 ? -21.916 -23.019 -2.348  1.00 31.23  ? 135 ASP B CB  1 
ATOM   4651  C CG  . ASP B 1 135 ? -22.169 -21.786 -3.209  1.00 31.76  ? 135 ASP B CG  1 
ATOM   4652  O OD1 . ASP B 1 135 ? -21.215 -21.300 -3.846  1.00 28.33  ? 135 ASP B OD1 1 
ATOM   4653  O OD2 . ASP B 1 135 ? -23.304 -21.295 -3.220  1.00 31.97  ? 135 ASP B OD2 1 
ATOM   4654  N N   . THR B 1 136 ? -18.960 -23.564 -4.354  1.00 25.99  ? 136 THR B N   1 
ATOM   4655  C CA  . THR B 1 136 ? -18.472 -24.075 -5.625  1.00 25.47  ? 136 THR B CA  1 
ATOM   4656  C C   . THR B 1 136 ? -18.122 -25.550 -5.464  1.00 26.30  ? 136 THR B C   1 
ATOM   4657  O O   . THR B 1 136 ? -17.544 -25.965 -4.454  1.00 26.53  ? 136 THR B O   1 
ATOM   4658  C CB  . THR B 1 136 ? -17.226 -23.313 -6.082  1.00 28.85  ? 136 THR B CB  1 
ATOM   4659  O OG1 . THR B 1 136 ? -17.555 -21.930 -6.185  1.00 30.36  ? 136 THR B OG1 1 
ATOM   4660  C CG2 . THR B 1 136 ? -16.664 -23.815 -7.385  1.00 30.85  ? 136 THR B CG2 1 
ATOM   4661  N N   . HIS B 1 137 ? -18.464 -26.338 -6.479  1.00 25.04  ? 137 HIS B N   1 
ATOM   4662  C CA  . HIS B 1 137 ? -18.163 -27.755 -6.463  1.00 29.80  ? 137 HIS B CA  1 
ATOM   4663  C C   . HIS B 1 137 ? -16.666 -27.978 -6.220  1.00 24.52  ? 137 HIS B C   1 
ATOM   4664  O O   . HIS B 1 137 ? -15.825 -27.304 -6.799  1.00 27.25  ? 137 HIS B O   1 
ATOM   4665  C CB  . HIS B 1 137 ? -18.591 -28.383 -7.791  1.00 29.64  ? 137 HIS B CB  1 
ATOM   4666  C CG  . HIS B 1 137 ? -18.576 -29.881 -7.757  1.00 35.03  ? 137 HIS B CG  1 
ATOM   4667  N ND1 . HIS B 1 137 ? -17.416 -30.616 -7.874  1.00 29.21  ? 137 HIS B ND1 1 
ATOM   4668  C CD2 . HIS B 1 137 ? -19.595 -30.793 -7.668  1.00 34.87  ? 137 HIS B CD2 1 
ATOM   4669  C CE1 . HIS B 1 137 ? -17.717 -31.919 -7.836  1.00 29.95  ? 137 HIS B CE1 1 
ATOM   4670  N NE2 . HIS B 1 137 ? -19.023 -32.043 -7.729  1.00 31.06  ? 137 HIS B NE2 1 
ATOM   4671  N N   . PRO B 1 138 ? -16.277 -28.955 -5.394  1.00 23.55  ? 138 PRO B N   1 
ATOM   4672  C CA  . PRO B 1 138 ? -14.875 -29.130 -5.015  1.00 23.45  ? 138 PRO B CA  1 
ATOM   4673  C C   . PRO B 1 138 ? -13.982 -29.512 -6.172  1.00 24.79  ? 138 PRO B C   1 
ATOM   4674  O O   . PRO B 1 138 ? -12.805 -29.177 -6.158  1.00 26.25  ? 138 PRO B O   1 
ATOM   4675  C CB  . PRO B 1 138 ? -14.929 -30.242 -3.969  1.00 24.95  ? 138 PRO B CB  1 
ATOM   4676  C CG  . PRO B 1 138 ? -16.213 -30.983 -4.302  1.00 28.09  ? 138 PRO B CG  1 
ATOM   4677  C CD  . PRO B 1 138 ? -17.170 -29.866 -4.674  1.00 25.61  ? 138 PRO B CD  1 
ATOM   4678  N N   . MET B 1 139 ? -14.530 -30.151 -7.223  1.00 23.06  ? 139 MET B N   1 
ATOM   4679  C CA  . MET B 1 139 ? -13.694 -30.448 -8.383  1.00 22.96  ? 139 MET B CA  1 
ATOM   4680  C C   . MET B 1 139 ? -13.435 -29.181 -9.201  1.00 22.80  ? 139 MET B C   1 
ATOM   4681  O O   . MET B 1 139 ? -12.413 -29.092 -9.890  1.00 26.00  ? 139 MET B O   1 
ATOM   4682  C CB  . MET B 1 139 ? -14.333 -31.544 -9.244  1.00 25.60  ? 139 MET B CB  1 
ATOM   4683  C CG  . MET B 1 139 ? -14.142 -32.927 -8.643  1.00 26.31  ? 139 MET B CG  1 
ATOM   4684  S SD  . MET B 1 139 ? -12.451 -33.471 -8.804  1.00 29.91  ? 139 MET B SD  1 
ATOM   4685  C CE  . MET B 1 139 ? -12.223 -33.667 -10.562 1.00 31.56  ? 139 MET B CE  1 
ATOM   4686  N N   . THR B 1 140 ? -14.335 -28.188 -9.129  1.00 24.00  ? 140 THR B N   1 
ATOM   4687  C CA  . THR B 1 140 ? -14.092 -26.918 -9.812  1.00 24.40  ? 140 THR B CA  1 
ATOM   4688  C C   . THR B 1 140 ? -12.961 -26.191 -9.088  1.00 24.79  ? 140 THR B C   1 
ATOM   4689  O O   . THR B 1 140 ? -12.043 -25.698 -9.727  1.00 24.60  ? 140 THR B O   1 
ATOM   4690  C CB  . THR B 1 140 ? -15.348 -26.041 -9.931  1.00 24.42  ? 140 THR B CB  1 
ATOM   4691  O OG1 . THR B 1 140 ? -16.300 -26.805 -10.675 1.00 23.57  ? 140 THR B OG1 1 
ATOM   4692  C CG2 . THR B 1 140 ? -15.088 -24.702 -10.586 1.00 25.24  ? 140 THR B CG2 1 
ATOM   4693  N N   . MET B 1 141 ? -13.006 -26.173 -7.750  1.00 23.99  ? 141 MET B N   1 
ATOM   4694  C CA  . MET B 1 141 ? -11.963 -25.580 -6.943  1.00 24.41  ? 141 MET B CA  1 
ATOM   4695  C C   . MET B 1 141 ? -10.623 -26.303 -7.177  1.00 25.16  ? 141 MET B C   1 
ATOM   4696  O O   . MET B 1 141 ? -9.571  -25.663 -7.240  1.00 25.14  ? 141 MET B O   1 
ATOM   4697  C CB  . MET B 1 141 ? -12.327 -25.691 -5.470  1.00 26.41  ? 141 MET B CB  1 
ATOM   4698  C CG  . MET B 1 141 ? -13.554 -24.919 -5.058  1.00 24.04  ? 141 MET B CG  1 
ATOM   4699  S SD  . MET B 1 141 ? -13.645 -25.088 -3.249  1.00 29.03  ? 141 MET B SD  1 
ATOM   4700  C CE  . MET B 1 141 ? -15.031 -24.024 -2.843  1.00 34.36  ? 141 MET B CE  1 
ATOM   4701  N N   . PHE B 1 142 ? -10.645 -27.635 -7.252  1.00 21.76  ? 142 PHE B N   1 
ATOM   4702  C CA  . PHE B 1 142 ? -9.419  -28.417 -7.393  1.00 23.37  ? 142 PHE B CA  1 
ATOM   4703  C C   . PHE B 1 142 ? -8.722  -28.048 -8.700  1.00 24.48  ? 142 PHE B C   1 
ATOM   4704  O O   . PHE B 1 142 ? -7.536  -27.705 -8.706  1.00 23.67  ? 142 PHE B O   1 
ATOM   4705  C CB  . PHE B 1 142 ? -9.751  -29.902 -7.286  1.00 24.96  ? 142 PHE B CB  1 
ATOM   4706  C CG  . PHE B 1 142 ? -8.564  -30.826 -7.252  1.00 24.71  ? 142 PHE B CG  1 
ATOM   4707  C CD1 . PHE B 1 142 ? -7.550  -30.654 -6.316  1.00 24.20  ? 142 PHE B CD1 1 
ATOM   4708  C CD2 . PHE B 1 142 ? -8.501  -31.916 -8.107  1.00 26.79  ? 142 PHE B CD2 1 
ATOM   4709  C CE1 . PHE B 1 142 ? -6.475  -31.522 -6.259  1.00 25.79  ? 142 PHE B CE1 1 
ATOM   4710  C CE2 . PHE B 1 142 ? -7.437  -32.812 -8.025  1.00 27.07  ? 142 PHE B CE2 1 
ATOM   4711  C CZ  . PHE B 1 142 ? -6.411  -32.593 -7.132  1.00 27.29  ? 142 PHE B CZ  1 
ATOM   4712  N N   . ALA B 1 143 ? -9.488  -28.037 -9.798  1.00 22.78  ? 143 ALA B N   1 
ATOM   4713  C CA  . ALA B 1 143 ? -8.923  -27.729 -11.104 1.00 23.70  ? 143 ALA B CA  1 
ATOM   4714  C C   . ALA B 1 143 ? -8.384  -26.303 -11.165 1.00 24.11  ? 143 ALA B C   1 
ATOM   4715  O O   . ALA B 1 143 ? -7.327  -26.073 -11.742 1.00 23.94  ? 143 ALA B O   1 
ATOM   4716  C CB  . ALA B 1 143 ? -9.950  -27.985 -12.182 1.00 23.25  ? 143 ALA B CB  1 
ATOM   4717  N N   . ALA B 1 144 ? -9.102  -25.363 -10.549 1.00 23.95  ? 144 ALA B N   1 
ATOM   4718  C CA  . ALA B 1 144 ? -8.729  -23.966 -10.551 1.00 24.91  ? 144 ALA B CA  1 
ATOM   4719  C C   . ALA B 1 144 ? -7.427  -23.755 -9.784  1.00 26.59  ? 144 ALA B C   1 
ATOM   4720  O O   . ALA B 1 144 ? -6.591  -22.944 -10.185 1.00 26.32  ? 144 ALA B O   1 
ATOM   4721  C CB  . ALA B 1 144 ? -9.856  -23.155 -9.936  1.00 26.86  ? 144 ALA B CB  1 
ATOM   4722  N N   . GLY B 1 145 ? -7.319  -24.388 -8.615  1.00 24.40  ? 145 GLY B N   1 
ATOM   4723  C CA  . GLY B 1 145 ? -6.131  -24.276 -7.797  1.00 26.86  ? 145 GLY B CA  1 
ATOM   4724  C C   . GLY B 1 145 ? -4.878  -24.764 -8.540  1.00 27.90  ? 145 GLY B C   1 
ATOM   4725  O O   . GLY B 1 145 ? -3.822  -24.116 -8.499  1.00 25.43  ? 145 GLY B O   1 
ATOM   4726  N N   . ILE B 1 146 ? -5.009  -25.920 -9.205  1.00 24.63  ? 146 ILE B N   1 
ATOM   4727  C CA  . ILE B 1 146 ? -3.944  -26.511 -10.002 1.00 24.35  ? 146 ILE B CA  1 
ATOM   4728  C C   . ILE B 1 146 ? -3.517  -25.557 -11.111 1.00 25.97  ? 146 ILE B C   1 
ATOM   4729  O O   . ILE B 1 146 ? -2.323  -25.345 -11.370 1.00 23.78  ? 146 ILE B O   1 
ATOM   4730  C CB  . ILE B 1 146 ? -4.376  -27.877 -10.573 1.00 27.93  ? 146 ILE B CB  1 
ATOM   4731  C CG1 . ILE B 1 146 ? -4.595  -28.893 -9.461  1.00 27.04  ? 146 ILE B CG1 1 
ATOM   4732  C CG2 . ILE B 1 146 ? -3.354  -28.396 -11.592 1.00 30.11  ? 146 ILE B CG2 1 
ATOM   4733  C CD1 . ILE B 1 146 ? -5.470  -30.066 -9.862  1.00 29.98  ? 146 ILE B CD1 1 
ATOM   4734  N N   . LEU B 1 147 ? -4.508  -25.032 -11.823 1.00 24.46  ? 147 LEU B N   1 
ATOM   4735  C CA  . LEU B 1 147 ? -4.220  -24.229 -12.995 1.00 26.65  ? 147 LEU B CA  1 
ATOM   4736  C C   . LEU B 1 147 ? -3.548  -22.922 -12.567 1.00 25.25  ? 147 LEU B C   1 
ATOM   4737  O O   . LEU B 1 147 ? -2.664  -22.422 -13.233 1.00 27.11  ? 147 LEU B O   1 
ATOM   4738  C CB  . LEU B 1 147 ? -5.540  -23.961 -13.695 1.00 25.78  ? 147 LEU B CB  1 
ATOM   4739  C CG  . LEU B 1 147 ? -5.513  -23.003 -14.877 1.00 28.57  ? 147 LEU B CG  1 
ATOM   4740  C CD1 . LEU B 1 147 ? -4.563  -23.490 -15.957 1.00 29.95  ? 147 LEU B CD1 1 
ATOM   4741  C CD2 . LEU B 1 147 ? -6.914  -22.837 -15.417 1.00 29.30  ? 147 LEU B CD2 1 
ATOM   4742  N N   . ALA B 1 148 ? -3.960  -22.363 -11.439 1.00 26.67  ? 148 ALA B N   1 
ATOM   4743  C CA  . ALA B 1 148 ? -3.373  -21.107 -11.001 1.00 24.62  ? 148 ALA B CA  1 
ATOM   4744  C C   . ALA B 1 148 ? -1.860  -21.283 -10.799 1.00 28.29  ? 148 ALA B C   1 
ATOM   4745  O O   . ALA B 1 148 ? -1.074  -20.356 -11.026 1.00 26.51  ? 148 ALA B O   1 
ATOM   4746  C CB  . ALA B 1 148 ? -4.036  -20.663 -9.740  1.00 23.65  ? 148 ALA B CB  1 
ATOM   4747  N N   . MET B 1 149 ? -1.450  -22.505 -10.413 1.00 27.31  ? 149 MET B N   1 
ATOM   4748  C CA  . MET B 1 149 ? -0.061  -22.787 -10.115 1.00 25.42  ? 149 MET B CA  1 
ATOM   4749  C C   . MET B 1 149 ? 0.781   -22.947 -11.379 1.00 26.45  ? 149 MET B C   1 
ATOM   4750  O O   . MET B 1 149 ? 1.993   -23.066 -11.269 1.00 26.41  ? 149 MET B O   1 
ATOM   4751  C CB  . MET B 1 149 ? 0.014   -24.034 -9.240  1.00 27.92  ? 149 MET B CB  1 
ATOM   4752  C CG  . MET B 1 149 ? 1.323   -24.264 -8.596  1.00 31.62  ? 149 MET B CG  1 
ATOM   4753  S SD  . MET B 1 149 ? 1.158   -25.510 -7.283  1.00 32.00  ? 149 MET B SD  1 
ATOM   4754  C CE  . MET B 1 149 ? 2.916   -25.682 -6.960  1.00 36.33  ? 149 MET B CE  1 
ATOM   4755  N N   . GLN B 1 150 ? 0.168   -22.843 -12.566 1.00 24.05  ? 150 GLN B N   1 
ATOM   4756  C CA  . GLN B 1 150 ? 0.863   -22.847 -13.833 1.00 24.18  ? 150 GLN B CA  1 
ATOM   4757  C C   . GLN B 1 150 ? 1.938   -21.757 -13.910 1.00 26.45  ? 150 GLN B C   1 
ATOM   4758  O O   . GLN B 1 150 ? 2.903   -21.881 -14.667 1.00 27.47  ? 150 GLN B O   1 
ATOM   4759  C CB  . GLN B 1 150 ? -0.133  -22.645 -14.961 1.00 24.26  ? 150 GLN B CB  1 
ATOM   4760  C CG  . GLN B 1 150 ? 0.463   -22.799 -16.348 1.00 25.92  ? 150 GLN B CG  1 
ATOM   4761  C CD  . GLN B 1 150 ? 1.094   -21.563 -16.939 1.00 27.55  ? 150 GLN B CD  1 
ATOM   4762  O OE1 . GLN B 1 150 ? 0.771   -20.409 -16.606 1.00 28.51  ? 150 GLN B OE1 1 
ATOM   4763  N NE2 . GLN B 1 150 ? 2.064   -21.812 -17.808 1.00 26.84  ? 150 GLN B NE2 1 
ATOM   4764  N N   . ARG B 1 151 ? 1.744   -20.662 -13.174 1.00 26.47  ? 151 ARG B N   1 
ATOM   4765  C CA  . ARG B 1 151 ? 2.730   -19.598 -13.108 1.00 27.58  ? 151 ARG B CA  1 
ATOM   4766  C C   . ARG B 1 151 ? 4.102   -20.148 -12.735 1.00 23.76  ? 151 ARG B C   1 
ATOM   4767  O O   . ARG B 1 151 ? 5.081   -19.592 -13.153 1.00 24.93  ? 151 ARG B O   1 
ATOM   4768  C CB  . ARG B 1 151 ? 2.335   -18.509 -12.104 1.00 28.59  ? 151 ARG B CB  1 
ATOM   4769  C CG  . ARG B 1 151 ? 3.321   -17.334 -12.054 1.00 26.64  ? 151 ARG B CG  1 
ATOM   4770  C CD  . ARG B 1 151 ? 2.914   -16.478 -10.871 1.00 33.93  ? 151 ARG B CD  1 
ATOM   4771  N NE  . ARG B 1 151 ? 3.761   -15.304 -10.635 1.00 36.33  ? 151 ARG B NE  1 
ATOM   4772  C CZ  . ARG B 1 151 ? 4.789   -15.248 -9.798  1.00 38.07  ? 151 ARG B CZ  1 
ATOM   4773  N NH1 . ARG B 1 151 ? 5.195   -16.332 -9.131  1.00 34.23  ? 151 ARG B NH1 1 
ATOM   4774  N NH2 . ARG B 1 151 ? 5.484   -14.122 -9.739  1.00 37.57  ? 151 ARG B NH2 1 
ATOM   4775  N N   . GLU B 1 152 ? 4.159   -21.195 -11.919 1.00 25.49  ? 152 GLU B N   1 
ATOM   4776  C CA  . GLU B 1 152 ? 5.414   -21.782 -11.479 1.00 27.56  ? 152 GLU B CA  1 
ATOM   4777  C C   . GLU B 1 152 ? 5.991   -22.826 -12.459 1.00 29.85  ? 152 GLU B C   1 
ATOM   4778  O O   . GLU B 1 152 ? 6.936   -23.529 -12.093 1.00 29.99  ? 152 GLU B O   1 
ATOM   4779  C CB  . GLU B 1 152 ? 5.194   -22.461 -10.121 1.00 27.80  ? 152 GLU B CB  1 
ATOM   4780  C CG  . GLU B 1 152 ? 4.617   -21.546 -9.041  1.00 30.45  ? 152 GLU B CG  1 
ATOM   4781  C CD  . GLU B 1 152 ? 5.168   -20.117 -9.002  1.00 32.34  ? 152 GLU B CD  1 
ATOM   4782  O OE1 . GLU B 1 152 ? 4.361   -19.154 -8.869  1.00 32.86  ? 152 GLU B OE1 1 
ATOM   4783  O OE2 . GLU B 1 152 ? 6.369   -19.949 -9.205  1.00 32.07  ? 152 GLU B OE2 1 
ATOM   4784  N N   . SER B 1 153 ? 5.488   -22.918 -13.704 1.00 28.11  ? 153 SER B N   1 
ATOM   4785  C CA  . SER B 1 153 ? 5.888   -24.017 -14.575 1.00 29.94  ? 153 SER B CA  1 
ATOM   4786  C C   . SER B 1 153 ? 7.307   -23.803 -15.109 1.00 26.78  ? 153 SER B C   1 
ATOM   4787  O O   . SER B 1 153 ? 7.572   -22.845 -15.812 1.00 25.95  ? 153 SER B O   1 
ATOM   4788  C CB  . SER B 1 153 ? 4.927   -24.201 -15.732 1.00 31.23  ? 153 SER B CB  1 
ATOM   4789  O OG  . SER B 1 153 ? 5.406   -25.173 -16.647 1.00 29.42  ? 153 SER B OG  1 
ATOM   4790  N N   . VAL B 1 154 ? 8.144   -24.807 -14.909 1.00 30.16  ? 154 VAL B N   1 
ATOM   4791  C CA  . VAL B 1 154 ? 9.517   -24.833 -15.408 1.00 30.62  ? 154 VAL B CA  1 
ATOM   4792  C C   . VAL B 1 154 ? 9.504   -25.154 -16.900 1.00 33.02  ? 154 VAL B C   1 
ATOM   4793  O O   . VAL B 1 154 ? 10.228  -24.537 -17.676 1.00 34.21  ? 154 VAL B O   1 
ATOM   4794  C CB  . VAL B 1 154 ? 10.313  -25.856 -14.575 1.00 35.00  ? 154 VAL B CB  1 
ATOM   4795  C CG1 . VAL B 1 154 ? 11.672  -26.186 -15.171 1.00 41.54  ? 154 VAL B CG1 1 
ATOM   4796  C CG2 . VAL B 1 154 ? 10.471  -25.348 -13.151 1.00 37.16  ? 154 VAL B CG2 1 
ATOM   4797  N N   . PHE B 1 155 ? 8.618   -26.079 -17.304 1.00 31.87  ? 155 PHE B N   1 
ATOM   4798  C CA  . PHE B 1 155 ? 8.481   -26.415 -18.716 1.00 31.15  ? 155 PHE B CA  1 
ATOM   4799  C C   . PHE B 1 155 ? 8.102   -25.159 -19.492 1.00 32.64  ? 155 PHE B C   1 
ATOM   4800  O O   . PHE B 1 155 ? 8.688   -24.851 -20.539 1.00 34.11  ? 155 PHE B O   1 
ATOM   4801  C CB  . PHE B 1 155 ? 7.508   -27.592 -18.900 1.00 34.31  ? 155 PHE B CB  1 
ATOM   4802  C CG  . PHE B 1 155 ? 7.368   -28.047 -20.334 1.00 31.61  ? 155 PHE B CG  1 
ATOM   4803  C CD1 . PHE B 1 155 ? 6.657   -27.298 -21.257 1.00 34.43  ? 155 PHE B CD1 1 
ATOM   4804  C CD2 . PHE B 1 155 ? 8.021   -29.188 -20.776 1.00 37.54  ? 155 PHE B CD2 1 
ATOM   4805  C CE1 . PHE B 1 155 ? 6.547   -27.712 -22.578 1.00 40.81  ? 155 PHE B CE1 1 
ATOM   4806  C CE2 . PHE B 1 155 ? 7.918   -29.592 -22.099 1.00 37.91  ? 155 PHE B CE2 1 
ATOM   4807  C CZ  . PHE B 1 155 ? 7.157   -28.873 -22.988 1.00 35.53  ? 155 PHE B CZ  1 
ATOM   4808  N N   . ALA B 1 156 ? 7.090   -24.420 -19.013 1.00 32.59  ? 156 ALA B N   1 
ATOM   4809  C CA  . ALA B 1 156 ? 6.644   -23.275 -19.784 1.00 33.18  ? 156 ALA B CA  1 
ATOM   4810  C C   . ALA B 1 156 ? 7.779   -22.247 -19.882 1.00 32.06  ? 156 ALA B C   1 
ATOM   4811  O O   . ALA B 1 156 ? 8.005   -21.671 -20.944 1.00 34.78  ? 156 ALA B O   1 
ATOM   4812  C CB  . ALA B 1 156 ? 5.365   -22.684 -19.205 1.00 35.17  ? 156 ALA B CB  1 
ATOM   4813  N N   . LYS B 1 157 ? 8.485   -22.030 -18.775 1.00 35.21  ? 157 LYS B N   1 
ATOM   4814  C CA  . LYS B 1 157 ? 9.567   -21.059 -18.715 1.00 36.41  ? 157 LYS B CA  1 
ATOM   4815  C C   . LYS B 1 157 ? 10.716  -21.475 -19.644 1.00 36.04  ? 157 LYS B C   1 
ATOM   4816  O O   . LYS B 1 157 ? 11.148  -20.689 -20.491 1.00 37.74  ? 157 LYS B O   1 
ATOM   4817  C CB  . LYS B 1 157 ? 10.026  -20.927 -17.261 1.00 40.05  ? 157 LYS B CB  1 
ATOM   4818  C CG  . LYS B 1 157 ? 11.086  -19.855 -17.024 1.00 47.68  ? 157 LYS B CG  1 
ATOM   4819  C CD  . LYS B 1 157 ? 11.723  -19.878 -15.645 1.00 55.14  ? 157 LYS B CD  1 
ATOM   4820  C CE  . LYS B 1 157 ? 12.963  -19.006 -15.598 1.00 67.73  ? 157 LYS B CE  1 
ATOM   4821  N NZ  . LYS B 1 157 ? 13.567  -18.968 -14.247 1.00 74.36  ? 157 LYS B NZ  1 
ATOM   4822  N N   . ARG B 1 158 ? 11.180  -22.726 -19.516 1.00 36.80  ? 158 ARG B N   1 
ATOM   4823  C CA  . ARG B 1 158 ? 12.267  -23.247 -20.349 1.00 39.16  ? 158 ARG B CA  1 
ATOM   4824  C C   . ARG B 1 158 ? 11.893  -23.271 -21.839 1.00 40.30  ? 158 ARG B C   1 
ATOM   4825  O O   . ARG B 1 158 ? 12.704  -22.917 -22.716 1.00 39.61  ? 158 ARG B O   1 
ATOM   4826  C CB  . ARG B 1 158 ? 12.679  -24.616 -19.809 1.00 41.48  ? 158 ARG B CB  1 
ATOM   4827  C CG  . ARG B 1 158 ? 13.294  -24.540 -18.418 1.00 50.99  ? 158 ARG B CG  1 
ATOM   4828  C CD  . ARG B 1 158 ? 14.561  -25.353 -18.217 1.00 65.74  ? 158 ARG B CD  1 
ATOM   4829  N NE  . ARG B 1 158 ? 14.400  -26.501 -17.327 1.00 69.72  ? 158 ARG B NE  1 
ATOM   4830  C CZ  . ARG B 1 158 ? 14.859  -27.730 -17.574 1.00 69.07  ? 158 ARG B CZ  1 
ATOM   4831  N NH1 . ARG B 1 158 ? 14.724  -28.669 -16.656 1.00 56.21  ? 158 ARG B NH1 1 
ATOM   4832  N NH2 . ARG B 1 158 ? 15.470  -28.013 -18.722 1.00 77.74  ? 158 ARG B NH2 1 
ATOM   4833  N N   . TYR B 1 159 ? 10.636  -23.606 -22.157 1.00 38.43  ? 159 TYR B N   1 
ATOM   4834  C CA  . TYR B 1 159 ? 10.218  -23.615 -23.552 1.00 37.71  ? 159 TYR B CA  1 
ATOM   4835  C C   . TYR B 1 159 ? 10.368  -22.232 -24.194 1.00 42.64  ? 159 TYR B C   1 
ATOM   4836  O O   . TYR B 1 159 ? 10.847  -22.145 -25.322 1.00 39.31  ? 159 TYR B O   1 
ATOM   4837  C CB  . TYR B 1 159 ? 8.765   -24.059 -23.732 1.00 43.72  ? 159 TYR B CB  1 
ATOM   4838  C CG  . TYR B 1 159 ? 8.454   -24.346 -25.179 1.00 45.12  ? 159 TYR B CG  1 
ATOM   4839  C CD1 . TYR B 1 159 ? 8.766   -25.574 -25.737 1.00 50.43  ? 159 TYR B CD1 1 
ATOM   4840  C CD2 . TYR B 1 159 ? 7.971   -23.353 -26.017 1.00 47.16  ? 159 TYR B CD2 1 
ATOM   4841  C CE1 . TYR B 1 159 ? 8.520   -25.835 -27.078 1.00 51.32  ? 159 TYR B CE1 1 
ATOM   4842  C CE2 . TYR B 1 159 ? 7.739   -23.589 -27.362 1.00 48.27  ? 159 TYR B CE2 1 
ATOM   4843  C CZ  . TYR B 1 159 ? 8.021   -24.835 -27.894 1.00 52.93  ? 159 TYR B CZ  1 
ATOM   4844  O OH  . TYR B 1 159 ? 7.774   -25.095 -29.219 1.00 59.55  ? 159 TYR B OH  1 
ATOM   4845  N N   . GLU B 1 160 ? 9.864   -21.181 -23.521 1.00 42.69  ? 160 GLU B N   1 
ATOM   4846  C CA  . GLU B 1 160 ? 9.944   -19.795 -23.983 1.00 48.56  ? 160 GLU B CA  1 
ATOM   4847  C C   . GLU B 1 160 ? 11.405  -19.338 -24.102 1.00 44.80  ? 160 GLU B C   1 
ATOM   4848  O O   . GLU B 1 160 ? 11.714  -18.610 -25.034 1.00 46.19  ? 160 GLU B O   1 
ATOM   4849  C CB  . GLU B 1 160 ? 9.189   -18.801 -23.075 1.00 52.27  ? 160 GLU B CB  1 
ATOM   4850  C CG  . GLU B 1 160 ? 7.675   -19.004 -23.022 1.00 73.76  ? 160 GLU B CG  1 
ATOM   4851  C CD  . GLU B 1 160 ? 6.891   -18.274 -21.925 1.00 92.27  ? 160 GLU B CD  1 
ATOM   4852  O OE1 . GLU B 1 160 ? 5.791   -17.739 -22.235 1.00 94.71  ? 160 GLU B OE1 1 
ATOM   4853  O OE2 . GLU B 1 160 ? 7.352   -18.248 -20.747 1.00 88.96  ? 160 GLU B OE2 1 
ATOM   4854  N N   . GLU B 1 161 ? 12.297  -19.754 -23.182 1.00 47.81  ? 161 GLU B N   1 
ATOM   4855  C CA  . GLU B 1 161 ? 13.723  -19.438 -23.258 1.00 51.33  ? 161 GLU B CA  1 
ATOM   4856  C C   . GLU B 1 161 ? 14.448  -20.203 -24.374 1.00 52.10  ? 161 GLU B C   1 
ATOM   4857  O O   . GLU B 1 161 ? 15.602  -19.924 -24.644 1.00 55.04  ? 161 GLU B O   1 
ATOM   4858  C CB  . GLU B 1 161 ? 14.450  -19.813 -21.964 1.00 53.92  ? 161 GLU B CB  1 
ATOM   4859  C CG  . GLU B 1 161 ? 14.147  -18.903 -20.775 1.00 59.55  ? 161 GLU B CG  1 
ATOM   4860  C CD  . GLU B 1 161 ? 14.561  -19.443 -19.404 1.00 58.53  ? 161 GLU B CD  1 
ATOM   4861  O OE1 . GLU B 1 161 ? 14.460  -18.683 -18.419 1.00 64.42  ? 161 GLU B OE1 1 
ATOM   4862  O OE2 . GLU B 1 161 ? 14.976  -20.625 -19.308 1.00 54.57  ? 161 GLU B OE2 1 
ATOM   4863  N N   . GLY B 1 162 ? 13.822  -21.217 -24.974 1.00 54.05  ? 162 GLY B N   1 
ATOM   4864  C CA  . GLY B 1 162 ? 14.506  -22.089 -25.916 1.00 54.56  ? 162 GLY B CA  1 
ATOM   4865  C C   . GLY B 1 162 ? 15.251  -23.210 -25.197 1.00 57.22  ? 162 GLY B C   1 
ATOM   4866  O O   . GLY B 1 162 ? 16.240  -22.959 -24.509 1.00 62.28  ? 162 GLY B O   1 
ATOM   4867  N N   . MET B 1 163 ? 14.713  -24.430 -25.299 1.00 49.43  ? 163 MET B N   1 
ATOM   4868  C CA  . MET B 1 163 ? 15.377  -25.623 -24.811 1.00 47.84  ? 163 MET B CA  1 
ATOM   4869  C C   . MET B 1 163 ? 15.248  -26.674 -25.912 1.00 48.92  ? 163 MET B C   1 
ATOM   4870  O O   . MET B 1 163 ? 14.371  -26.568 -26.763 1.00 46.00  ? 163 MET B O   1 
ATOM   4871  C CB  . MET B 1 163 ? 14.763  -26.135 -23.499 1.00 48.47  ? 163 MET B CB  1 
ATOM   4872  C CG  . MET B 1 163 ? 13.414  -26.845 -23.638 1.00 50.43  ? 163 MET B CG  1 
ATOM   4873  S SD  . MET B 1 163 ? 12.750  -27.592 -22.087 1.00 45.78  ? 163 MET B SD  1 
ATOM   4874  C CE  . MET B 1 163 ? 11.023  -27.197 -22.306 1.00 41.59  ? 163 MET B CE  1 
ATOM   4875  N N   . ARG B 1 164 ? 16.109  -27.689 -25.887 1.00 56.16  ? 164 ARG B N   1 
ATOM   4876  C CA  . ARG B 1 164 ? 16.049  -28.773 -26.856 1.00 59.38  ? 164 ARG B CA  1 
ATOM   4877  C C   . ARG B 1 164 ? 14.899  -29.710 -26.495 1.00 53.18  ? 164 ARG B C   1 
ATOM   4878  O O   . ARG B 1 164 ? 14.543  -29.803 -25.332 1.00 45.39  ? 164 ARG B O   1 
ATOM   4879  C CB  . ARG B 1 164 ? 17.386  -29.514 -26.856 1.00 63.29  ? 164 ARG B CB  1 
ATOM   4880  C CG  . ARG B 1 164 ? 18.494  -28.794 -27.611 1.00 72.54  ? 164 ARG B CG  1 
ATOM   4881  C CD  . ARG B 1 164 ? 19.857  -28.990 -26.960 1.00 83.19  ? 164 ARG B CD  1 
ATOM   4882  N NE  . ARG B 1 164 ? 19.989  -30.258 -26.241 1.00 95.93  ? 164 ARG B NE  1 
ATOM   4883  C CZ  . ARG B 1 164 ? 20.163  -31.451 -26.808 1.00 100.53 ? 164 ARG B CZ  1 
ATOM   4884  N NH1 . ARG B 1 164 ? 20.345  -31.546 -28.114 1.00 109.61 ? 164 ARG B NH1 1 
ATOM   4885  N NH2 . ARG B 1 164 ? 20.178  -32.544 -26.059 1.00 92.58  ? 164 ARG B NH2 1 
ATOM   4886  N N   . ARG B 1 165 ? 14.350  -30.422 -27.491 1.00 57.04  ? 165 ARG B N   1 
ATOM   4887  C CA  . ARG B 1 165 ? 13.254  -31.364 -27.288 1.00 58.19  ? 165 ARG B CA  1 
ATOM   4888  C C   . ARG B 1 165 ? 13.683  -32.426 -26.280 1.00 53.70  ? 165 ARG B C   1 
ATOM   4889  O O   . ARG B 1 165 ? 12.862  -32.940 -25.514 1.00 46.25  ? 165 ARG B O   1 
ATOM   4890  C CB  . ARG B 1 165 ? 12.840  -32.021 -28.614 1.00 65.00  ? 165 ARG B CB  1 
ATOM   4891  C CG  . ARG B 1 165 ? 12.459  -31.037 -29.713 1.00 76.43  ? 165 ARG B CG  1 
ATOM   4892  C CD  . ARG B 1 165 ? 12.326  -31.655 -31.099 1.00 80.27  ? 165 ARG B CD  1 
ATOM   4893  N NE  . ARG B 1 165 ? 11.034  -32.304 -31.293 1.00 84.21  ? 165 ARG B NE  1 
ATOM   4894  C CZ  . ARG B 1 165 ? 10.838  -33.451 -31.947 1.00 85.52  ? 165 ARG B CZ  1 
ATOM   4895  N NH1 . ARG B 1 165 ? 11.835  -34.027 -32.601 1.00 80.23  ? 165 ARG B NH1 1 
ATOM   4896  N NH2 . ARG B 1 165 ? 9.636   -34.008 -31.965 1.00 67.98  ? 165 ARG B NH2 1 
ATOM   4897  N N   . GLU B 1 166 ? 14.995  -32.711 -26.262 1.00 48.64  ? 166 GLU B N   1 
ATOM   4898  C CA  . GLU B 1 166 ? 15.584  -33.743 -25.416 1.00 51.80  ? 166 GLU B CA  1 
ATOM   4899  C C   . GLU B 1 166 ? 15.494  -33.376 -23.937 1.00 46.39  ? 166 GLU B C   1 
ATOM   4900  O O   . GLU B 1 166 ? 15.591  -34.238 -23.075 1.00 46.04  ? 166 GLU B O   1 
ATOM   4901  C CB  . GLU B 1 166 ? 17.056  -33.955 -25.800 1.00 55.37  ? 166 GLU B CB  1 
ATOM   4902  C CG  . GLU B 1 166 ? 17.255  -34.660 -27.145 1.00 64.09  ? 166 GLU B CG  1 
ATOM   4903  C CD  . GLU B 1 166 ? 17.190  -33.846 -28.436 1.00 78.80  ? 166 GLU B CD  1 
ATOM   4904  O OE1 . GLU B 1 166 ? 17.449  -34.442 -29.513 1.00 83.84  ? 166 GLU B OE1 1 
ATOM   4905  O OE2 . GLU B 1 166 ? 16.887  -32.622 -28.389 1.00 74.22  ? 166 GLU B OE2 1 
ATOM   4906  N N   . GLU B 1 167 ? 15.324  -32.089 -23.635 1.00 45.84  ? 167 GLU B N   1 
ATOM   4907  C CA  . GLU B 1 167 ? 15.196  -31.638 -22.255 1.00 47.07  ? 167 GLU B CA  1 
ATOM   4908  C C   . GLU B 1 167 ? 13.727  -31.573 -21.806 1.00 39.18  ? 167 GLU B C   1 
ATOM   4909  O O   . GLU B 1 167 ? 13.453  -31.349 -20.642 1.00 38.42  ? 167 GLU B O   1 
ATOM   4910  C CB  . GLU B 1 167 ? 15.764  -30.223 -22.108 1.00 52.40  ? 167 GLU B CB  1 
ATOM   4911  C CG  . GLU B 1 167 ? 17.147  -29.991 -22.709 1.00 66.02  ? 167 GLU B CG  1 
ATOM   4912  C CD  . GLU B 1 167 ? 17.552  -28.517 -22.670 1.00 69.94  ? 167 GLU B CD  1 
ATOM   4913  O OE1 . GLU B 1 167 ? 17.577  -27.936 -21.540 1.00 70.33  ? 167 GLU B OE1 1 
ATOM   4914  O OE2 . GLU B 1 167 ? 17.748  -27.913 -23.771 1.00 58.01  ? 167 GLU B OE2 1 
ATOM   4915  N N   . HIS B 1 168 ? 12.773  -31.713 -22.724 1.00 36.50  ? 168 HIS B N   1 
ATOM   4916  C CA  . HIS B 1 168 ? 11.370  -31.667 -22.354 1.00 37.59  ? 168 HIS B CA  1 
ATOM   4917  C C   . HIS B 1 168 ? 11.091  -32.553 -21.153 1.00 33.76  ? 168 HIS B C   1 
ATOM   4918  O O   . HIS B 1 168 ? 10.415  -32.120 -20.228 1.00 30.02  ? 168 HIS B O   1 
ATOM   4919  C CB  . HIS B 1 168 ? 10.457  -32.060 -23.519 1.00 37.52  ? 168 HIS B CB  1 
ATOM   4920  C CG  . HIS B 1 168 ? 10.425  -31.011 -24.567 1.00 38.12  ? 168 HIS B CG  1 
ATOM   4921  N ND1 . HIS B 1 168 ? 9.580   -31.047 -25.656 1.00 38.77  ? 168 HIS B ND1 1 
ATOM   4922  C CD2 . HIS B 1 168 ? 11.127  -29.875 -24.663 1.00 39.27  ? 168 HIS B CD2 1 
ATOM   4923  C CE1 . HIS B 1 168 ? 9.803   -29.967 -26.391 1.00 44.31  ? 168 HIS B CE1 1 
ATOM   4924  N NE2 . HIS B 1 168 ? 10.738  -29.239 -25.804 1.00 40.37  ? 168 HIS B NE2 1 
ATOM   4925  N N   . TRP B 1 169 ? 11.601  -33.793 -21.149 1.00 30.75  ? 169 TRP B N   1 
ATOM   4926  C CA  . TRP B 1 169 ? 11.184  -34.740 -20.127 1.00 29.95  ? 169 TRP B CA  1 
ATOM   4927  C C   . TRP B 1 169 ? 11.719  -34.317 -18.761 1.00 31.27  ? 169 TRP B C   1 
ATOM   4928  O O   . TRP B 1 169 ? 11.152  -34.707 -17.746 1.00 32.57  ? 169 TRP B O   1 
ATOM   4929  C CB  . TRP B 1 169 ? 11.619  -36.175 -20.448 1.00 33.87  ? 169 TRP B CB  1 
ATOM   4930  C CG  . TRP B 1 169 ? 13.092  -36.424 -20.318 1.00 34.65  ? 169 TRP B CG  1 
ATOM   4931  C CD1 . TRP B 1 169 ? 14.005  -36.442 -21.331 1.00 38.25  ? 169 TRP B CD1 1 
ATOM   4932  C CD2 . TRP B 1 169 ? 13.821  -36.753 -19.117 1.00 36.95  ? 169 TRP B CD2 1 
ATOM   4933  N NE1 . TRP B 1 169 ? 15.256  -36.718 -20.847 1.00 37.93  ? 169 TRP B NE1 1 
ATOM   4934  C CE2 . TRP B 1 169 ? 15.172  -36.932 -19.495 1.00 38.72  ? 169 TRP B CE2 1 
ATOM   4935  C CE3 . TRP B 1 169 ? 13.472  -36.939 -17.770 1.00 37.73  ? 169 TRP B CE3 1 
ATOM   4936  C CZ2 . TRP B 1 169 ? 16.163  -37.240 -18.566 1.00 41.32  ? 169 TRP B CZ2 1 
ATOM   4937  C CZ3 . TRP B 1 169 ? 14.456  -37.235 -16.850 1.00 37.02  ? 169 TRP B CZ3 1 
ATOM   4938  C CH2 . TRP B 1 169 ? 15.777  -37.415 -17.249 1.00 37.24  ? 169 TRP B CH2 1 
ATOM   4939  N N   . GLU B 1 170 ? 12.838  -33.582 -18.742 1.00 31.13  ? 170 GLU B N   1 
ATOM   4940  C CA  . GLU B 1 170 ? 13.441  -33.114 -17.492 1.00 36.49  ? 170 GLU B CA  1 
ATOM   4941  C C   . GLU B 1 170 ? 12.559  -32.047 -16.837 1.00 32.31  ? 170 GLU B C   1 
ATOM   4942  O O   . GLU B 1 170 ? 12.295  -32.086 -15.643 1.00 32.89  ? 170 GLU B O   1 
ATOM   4943  C CB  . GLU B 1 170 ? 14.849  -32.592 -17.771 1.00 44.32  ? 170 GLU B CB  1 
ATOM   4944  C CG  . GLU B 1 170 ? 15.709  -33.640 -18.477 1.00 53.95  ? 170 GLU B CG  1 
ATOM   4945  C CD  . GLU B 1 170 ? 17.179  -33.295 -18.640 1.00 63.89  ? 170 GLU B CD  1 
ATOM   4946  O OE1 . GLU B 1 170 ? 17.711  -33.572 -19.732 1.00 66.67  ? 170 GLU B OE1 1 
ATOM   4947  O OE2 . GLU B 1 170 ? 17.787  -32.756 -17.676 1.00 62.45  ? 170 GLU B OE2 1 
ATOM   4948  N N   . ALA B 1 171 ? 12.033  -31.148 -17.663 1.00 30.53  ? 171 ALA B N   1 
ATOM   4949  C CA  . ALA B 1 171 ? 11.204  -30.063 -17.189 1.00 30.33  ? 171 ALA B CA  1 
ATOM   4950  C C   . ALA B 1 171 ? 9.847   -30.614 -16.743 1.00 31.46  ? 171 ALA B C   1 
ATOM   4951  O O   . ALA B 1 171 ? 9.308   -30.171 -15.724 1.00 32.82  ? 171 ALA B O   1 
ATOM   4952  C CB  . ALA B 1 171 ? 11.134  -29.028 -18.282 1.00 31.42  ? 171 ALA B CB  1 
ATOM   4953  N N   . MET B 1 172 ? 9.329   -31.616 -17.473 1.00 33.15  ? 172 MET B N   1 
ATOM   4954  C CA  . MET B 1 172 ? 8.067   -32.260 -17.142 1.00 31.11  ? 172 MET B CA  1 
ATOM   4955  C C   . MET B 1 172 ? 8.196   -32.948 -15.793 1.00 30.81  ? 172 MET B C   1 
ATOM   4956  O O   . MET B 1 172 ? 7.254   -32.969 -14.985 1.00 31.70  ? 172 MET B O   1 
ATOM   4957  C CB  . MET B 1 172 ? 7.666   -33.308 -18.191 1.00 28.23  ? 172 MET B CB  1 
ATOM   4958  C CG  . MET B 1 172 ? 7.252   -32.730 -19.509 1.00 31.10  ? 172 MET B CG  1 
ATOM   4959  S SD  . MET B 1 172 ? 5.659   -31.844 -19.365 1.00 36.58  ? 172 MET B SD  1 
ATOM   4960  C CE  . MET B 1 172 ? 5.337   -31.343 -21.053 1.00 52.93  ? 172 MET B CE  1 
ATOM   4961  N N   . LEU B 1 173 ? 9.373   -33.519 -15.543 1.00 32.44  ? 173 LEU B N   1 
ATOM   4962  C CA  . LEU B 1 173 ? 9.603   -34.200 -14.282 1.00 30.77  ? 173 LEU B CA  1 
ATOM   4963  C C   . LEU B 1 173 ? 9.657   -33.210 -13.121 1.00 26.89  ? 173 LEU B C   1 
ATOM   4964  O O   . LEU B 1 173 ? 9.091   -33.480 -12.078 1.00 27.69  ? 173 LEU B O   1 
ATOM   4965  C CB  . LEU B 1 173 ? 10.876  -35.047 -14.334 1.00 33.97  ? 173 LEU B CB  1 
ATOM   4966  C CG  . LEU B 1 173 ? 11.289  -35.690 -13.006 1.00 34.70  ? 173 LEU B CG  1 
ATOM   4967  C CD1 . LEU B 1 173 ? 10.298  -36.755 -12.558 1.00 37.30  ? 173 LEU B CD1 1 
ATOM   4968  C CD2 . LEU B 1 173 ? 12.696  -36.293 -13.108 1.00 39.62  ? 173 LEU B CD2 1 
ATOM   4969  N N   . GLU B 1 174 ? 10.474  -32.174 -13.222 1.00 31.66  ? 174 GLU B N   1 
ATOM   4970  C CA  . GLU B 1 174 ? 10.510  -31.130 -12.202 1.00 32.24  ? 174 GLU B CA  1 
ATOM   4971  C C   . GLU B 1 174 ? 9.085   -30.611 -11.929 1.00 33.58  ? 174 GLU B C   1 
ATOM   4972  O O   . GLU B 1 174 ? 8.629   -30.563 -10.790 1.00 31.28  ? 174 GLU B O   1 
ATOM   4973  C CB  . GLU B 1 174 ? 11.443  -30.007 -12.660 1.00 39.71  ? 174 GLU B CB  1 
ATOM   4974  C CG  . GLU B 1 174 ? 11.700  -28.929 -11.608 1.00 43.68  ? 174 GLU B CG  1 
ATOM   4975  C CD  . GLU B 1 174 ? 12.534  -29.360 -10.407 1.00 52.50  ? 174 GLU B CD  1 
ATOM   4976  O OE1 . GLU B 1 174 ? 13.209  -30.435 -10.482 1.00 52.54  ? 174 GLU B OE1 1 
ATOM   4977  O OE2 . GLU B 1 174 ? 12.492  -28.627 -9.383  1.00 62.39  ? 174 GLU B OE2 1 
ATOM   4978  N N   . ASP B 1 175 ? 8.366   -30.199 -12.969 1.00 30.30  ? 175 ASP B N   1 
ATOM   4979  C CA  . ASP B 1 175 ? 6.994   -29.751 -12.752 1.00 28.85  ? 175 ASP B CA  1 
ATOM   4980  C C   . ASP B 1 175 ? 6.127   -30.795 -12.044 1.00 28.44  ? 175 ASP B C   1 
ATOM   4981  O O   . ASP B 1 175 ? 5.299   -30.446 -11.202 1.00 30.06  ? 175 ASP B O   1 
ATOM   4982  C CB  . ASP B 1 175 ? 6.339   -29.341 -14.058 1.00 24.57  ? 175 ASP B CB  1 
ATOM   4983  C CG  . ASP B 1 175 ? 6.768   -27.972 -14.524 1.00 26.99  ? 175 ASP B CG  1 
ATOM   4984  O OD1 . ASP B 1 175 ? 7.272   -27.182 -13.680 1.00 34.95  ? 175 ASP B OD1 1 
ATOM   4985  O OD2 . ASP B 1 175 ? 6.545   -27.683 -15.714 1.00 31.03  ? 175 ASP B OD2 1 
ATOM   4986  N N   . SER B 1 176 ? 6.306   -32.078 -12.361 1.00 29.81  ? 176 SER B N   1 
ATOM   4987  C CA  . SER B 1 176 ? 5.454   -33.116 -11.813 1.00 26.66  ? 176 SER B CA  1 
ATOM   4988  C C   . SER B 1 176 ? 5.729   -33.259 -10.325 1.00 29.26  ? 176 SER B C   1 
ATOM   4989  O O   . SER B 1 176 ? 4.833   -33.560 -9.557  1.00 29.74  ? 176 SER B O   1 
ATOM   4990  C CB  . SER B 1 176 ? 5.612   -34.450 -12.532 1.00 27.90  ? 176 SER B CB  1 
ATOM   4991  O OG  . SER B 1 176 ? 5.199   -34.415 -13.894 1.00 28.15  ? 176 SER B OG  1 
ATOM   4992  N N   . LEU B 1 177 ? 6.993   -33.127 -9.928  1.00 29.62  ? 177 LEU B N   1 
ATOM   4993  C CA  . LEU B 1 177 ? 7.319   -33.204 -8.517  1.00 32.89  ? 177 LEU B CA  1 
ATOM   4994  C C   . LEU B 1 177 ? 6.605   -32.074 -7.776  1.00 26.37  ? 177 LEU B C   1 
ATOM   4995  O O   . LEU B 1 177 ? 6.064   -32.301 -6.717  1.00 27.05  ? 177 LEU B O   1 
ATOM   4996  C CB  . LEU B 1 177 ? 8.841   -33.120 -8.334  1.00 31.19  ? 177 LEU B CB  1 
ATOM   4997  C CG  . LEU B 1 177 ? 9.613   -34.340 -8.844  1.00 32.21  ? 177 LEU B CG  1 
ATOM   4998  C CD1 . LEU B 1 177 ? 11.102  -34.018 -8.992  1.00 32.67  ? 177 LEU B CD1 1 
ATOM   4999  C CD2 . LEU B 1 177 ? 9.396   -35.529 -7.924  1.00 31.15  ? 177 LEU B CD2 1 
ATOM   5000  N N   . ASN B 1 178 ? 6.655   -30.863 -8.304  1.00 30.09  ? 178 ASN B N   1 
ATOM   5001  C CA  . ASN B 1 178 ? 6.012   -29.720 -7.652  1.00 30.10  ? 178 ASN B CA  1 
ATOM   5002  C C   . ASN B 1 178 ? 4.497   -29.906 -7.555  1.00 31.60  ? 178 ASN B C   1 
ATOM   5003  O O   . ASN B 1 178 ? 3.893   -29.674 -6.507  1.00 26.29  ? 178 ASN B O   1 
ATOM   5004  C CB  . ASN B 1 178 ? 6.373   -28.426 -8.386  1.00 28.49  ? 178 ASN B CB  1 
ATOM   5005  C CG  . ASN B 1 178 ? 7.822   -28.082 -8.168  1.00 27.16  ? 178 ASN B CG  1 
ATOM   5006  O OD1 . ASN B 1 178 ? 8.394   -28.552 -7.187  1.00 31.94  ? 178 ASN B OD1 1 
ATOM   5007  N ND2 . ASN B 1 178 ? 8.403   -27.324 -9.086  1.00 30.00  ? 178 ASN B ND2 1 
ATOM   5008  N N   . MET B 1 179 ? 3.883   -30.305 -8.671  1.00 26.41  ? 179 MET B N   1 
ATOM   5009  C CA  . MET B 1 179 ? 2.441   -30.396 -8.734  1.00 28.56  ? 179 MET B CA  1 
ATOM   5010  C C   . MET B 1 179 ? 1.937   -31.502 -7.816  1.00 30.29  ? 179 MET B C   1 
ATOM   5011  O O   . MET B 1 179 ? 0.967   -31.324 -7.058  1.00 26.43  ? 179 MET B O   1 
ATOM   5012  C CB  . MET B 1 179 ? 1.954   -30.644 -10.169 1.00 31.43  ? 179 MET B CB  1 
ATOM   5013  C CG  . MET B 1 179 ? 0.448   -30.526 -10.235 1.00 30.74  ? 179 MET B CG  1 
ATOM   5014  S SD  . MET B 1 179 ? -0.290  -30.992 -11.810 1.00 31.06  ? 179 MET B SD  1 
ATOM   5015  C CE  . MET B 1 179 ? -0.176  -32.759 -11.536 1.00 31.21  ? 179 MET B CE  1 
ATOM   5016  N N   . LEU B 1 180 ? 2.587   -32.662 -7.870  1.00 28.03  ? 180 LEU B N   1 
ATOM   5017  C CA  . LEU B 1 180 ? 2.135   -33.771 -7.037  1.00 27.70  ? 180 LEU B CA  1 
ATOM   5018  C C   . LEU B 1 180 ? 2.244   -33.407 -5.551  1.00 25.21  ? 180 LEU B C   1 
ATOM   5019  O O   . LEU B 1 180 ? 1.411   -33.814 -4.715  1.00 27.06  ? 180 LEU B O   1 
ATOM   5020  C CB  . LEU B 1 180 ? 2.987   -35.016 -7.365  1.00 30.63  ? 180 LEU B CB  1 
ATOM   5021  C CG  . LEU B 1 180 ? 2.641   -35.766 -8.654  1.00 30.77  ? 180 LEU B CG  1 
ATOM   5022  C CD1 . LEU B 1 180 ? 3.695   -36.816 -8.993  1.00 33.69  ? 180 LEU B CD1 1 
ATOM   5023  C CD2 . LEU B 1 180 ? 1.277   -36.407 -8.550  1.00 29.06  ? 180 LEU B CD2 1 
ATOM   5024  N N   . ALA B 1 181 ? 3.329   -32.720 -5.174  1.00 27.54  ? 181 ALA B N   1 
ATOM   5025  C CA  . ALA B 1 181 ? 3.474   -32.333 -3.772  1.00 27.72  ? 181 ALA B CA  1 
ATOM   5026  C C   . ALA B 1 181 ? 2.315   -31.402 -3.387  1.00 28.01  ? 181 ALA B C   1 
ATOM   5027  O O   . ALA B 1 181 ? 1.772   -31.489 -2.299  1.00 28.40  ? 181 ALA B O   1 
ATOM   5028  C CB  . ALA B 1 181 ? 4.813   -31.680 -3.582  1.00 28.03  ? 181 ALA B CB  1 
ATOM   5029  N N   . ALA B 1 182 ? 1.891   -30.550 -4.337  1.00 27.88  ? 182 ALA B N   1 
ATOM   5030  C CA  . ALA B 1 182 ? 0.891   -29.539 -4.060  1.00 26.86  ? 182 ALA B CA  1 
ATOM   5031  C C   . ALA B 1 182 ? -0.494  -30.148 -3.938  1.00 28.65  ? 182 ALA B C   1 
ATOM   5032  O O   . ALA B 1 182 ? -1.286  -29.626 -3.158  1.00 29.54  ? 182 ALA B O   1 
ATOM   5033  C CB  . ALA B 1 182 ? 0.900   -28.491 -5.124  1.00 25.41  ? 182 ALA B CB  1 
ATOM   5034  N N   . LEU B 1 183 ? -0.774  -31.243 -4.682  1.00 29.65  ? 183 LEU B N   1 
ATOM   5035  C CA  . LEU B 1 183 ? -2.143  -31.725 -4.820  1.00 27.79  ? 183 LEU B CA  1 
ATOM   5036  C C   . LEU B 1 183 ? -2.762  -31.970 -3.456  1.00 24.49  ? 183 LEU B C   1 
ATOM   5037  O O   . LEU B 1 183 ? -3.893  -31.544 -3.250  1.00 27.42  ? 183 LEU B O   1 
ATOM   5038  C CB  . LEU B 1 183 ? -2.270  -32.958 -5.716  1.00 25.07  ? 183 LEU B CB  1 
ATOM   5039  C CG  . LEU B 1 183 ? -1.979  -32.751 -7.206  1.00 27.24  ? 183 LEU B CG  1 
ATOM   5040  C CD1 . LEU B 1 183 ? -2.396  -33.973 -7.976  1.00 30.29  ? 183 LEU B CD1 1 
ATOM   5041  C CD2 . LEU B 1 183 ? -2.704  -31.565 -7.771  1.00 28.45  ? 183 LEU B CD2 1 
ATOM   5042  N N   . PRO B 1 184 ? -2.144  -32.697 -2.508  1.00 27.72  ? 184 PRO B N   1 
ATOM   5043  C CA  . PRO B 1 184 ? -2.797  -32.956 -1.220  1.00 26.52  ? 184 PRO B CA  1 
ATOM   5044  C C   . PRO B 1 184 ? -3.074  -31.706 -0.396  1.00 26.03  ? 184 PRO B C   1 
ATOM   5045  O O   . PRO B 1 184 ? -4.028  -31.684 0.362   1.00 28.17  ? 184 PRO B O   1 
ATOM   5046  C CB  . PRO B 1 184 ? -1.806  -33.828 -0.437  1.00 28.82  ? 184 PRO B CB  1 
ATOM   5047  C CG  . PRO B 1 184 ? -0.850  -34.367 -1.462  1.00 30.79  ? 184 PRO B CG  1 
ATOM   5048  C CD  . PRO B 1 184 ? -0.879  -33.424 -2.637  1.00 29.41  ? 184 PRO B CD  1 
ATOM   5049  N N   . VAL B 1 185 ? -2.202  -30.695 -0.532  1.00 27.51  ? 185 VAL B N   1 
ATOM   5050  C CA  . VAL B 1 185 ? -2.368  -29.408 0.138   1.00 26.88  ? 185 VAL B CA  1 
ATOM   5051  C C   . VAL B 1 185 ? -3.601  -28.680 -0.399  1.00 25.95  ? 185 VAL B C   1 
ATOM   5052  O O   . VAL B 1 185 ? -4.424  -28.199 0.385   1.00 26.03  ? 185 VAL B O   1 
ATOM   5053  C CB  . VAL B 1 185 ? -1.091  -28.554 0.018   1.00 27.88  ? 185 VAL B CB  1 
ATOM   5054  C CG1 . VAL B 1 185 ? -1.285  -27.182 0.653   1.00 32.18  ? 185 VAL B CG1 1 
ATOM   5055  C CG2 . VAL B 1 185 ? 0.123   -29.257 0.629   1.00 30.40  ? 185 VAL B CG2 1 
ATOM   5056  N N   . ILE B 1 186 ? -3.749  -28.628 -1.719  1.00 23.67  ? 186 ILE B N   1 
ATOM   5057  C CA  . ILE B 1 186 ? -4.899  -27.981 -2.361  1.00 24.68  ? 186 ILE B CA  1 
ATOM   5058  C C   . ILE B 1 186 ? -6.179  -28.713 -1.984  1.00 25.35  ? 186 ILE B C   1 
ATOM   5059  O O   . ILE B 1 186 ? -7.170  -28.106 -1.548  1.00 24.53  ? 186 ILE B O   1 
ATOM   5060  C CB  . ILE B 1 186 ? -4.644  -27.887 -3.884  1.00 25.74  ? 186 ILE B CB  1 
ATOM   5061  C CG1 . ILE B 1 186 ? -3.460  -26.973 -4.172  1.00 26.05  ? 186 ILE B CG1 1 
ATOM   5062  C CG2 . ILE B 1 186 ? -5.873  -27.471 -4.687  1.00 25.63  ? 186 ILE B CG2 1 
ATOM   5063  C CD1 . ILE B 1 186 ? -3.033  -26.986 -5.620  1.00 30.59  ? 186 ILE B CD1 1 
ATOM   5064  N N   . ALA B 1 187 ? -6.129  -30.043 -2.061  1.00 27.16  ? 187 ALA B N   1 
ATOM   5065  C CA  . ALA B 1 187 ? -7.279  -30.894 -1.786  1.00 25.56  ? 187 ALA B CA  1 
ATOM   5066  C C   . ALA B 1 187 ? -7.732  -30.738 -0.347  1.00 24.78  ? 187 ALA B C   1 
ATOM   5067  O O   . ALA B 1 187 ? -8.921  -30.603 -0.064  1.00 24.62  ? 187 ALA B O   1 
ATOM   5068  C CB  . ALA B 1 187 ? -6.950  -32.333 -2.097  1.00 28.10  ? 187 ALA B CB  1 
ATOM   5069  N N   . ALA B 1 188 ? -6.771  -30.749 0.565   1.00 23.99  ? 188 ALA B N   1 
ATOM   5070  C CA  . ALA B 1 188 ? -7.120  -30.599 1.953   1.00 24.45  ? 188 ALA B CA  1 
ATOM   5071  C C   . ALA B 1 188 ? -7.672  -29.195 2.185   1.00 24.16  ? 188 ALA B C   1 
ATOM   5072  O O   . ALA B 1 188 ? -8.591  -29.037 2.961   1.00 25.54  ? 188 ALA B O   1 
ATOM   5073  C CB  . ALA B 1 188 ? -5.904  -30.853 2.819   1.00 25.81  ? 188 ALA B CB  1 
ATOM   5074  N N   . TYR B 1 189 ? -7.108  -28.161 1.546   1.00 27.34  ? 189 TYR B N   1 
ATOM   5075  C CA  . TYR B 1 189 ? -7.619  -26.812 1.767   1.00 24.42  ? 189 TYR B CA  1 
ATOM   5076  C C   . TYR B 1 189 ? -9.123  -26.754 1.451   1.00 25.43  ? 189 TYR B C   1 
ATOM   5077  O O   . TYR B 1 189 ? -9.951  -26.200 2.198   1.00 22.79  ? 189 TYR B O   1 
ATOM   5078  C CB  . TYR B 1 189 ? -6.783  -25.819 0.957   1.00 26.40  ? 189 TYR B CB  1 
ATOM   5079  C CG  . TYR B 1 189 ? -7.058  -24.396 1.361   1.00 28.48  ? 189 TYR B CG  1 
ATOM   5080  C CD1 . TYR B 1 189 ? -8.111  -23.685 0.812   1.00 29.22  ? 189 TYR B CD1 1 
ATOM   5081  C CD2 . TYR B 1 189 ? -6.337  -23.818 2.395   1.00 31.28  ? 189 TYR B CD2 1 
ATOM   5082  C CE1 . TYR B 1 189 ? -8.369  -22.381 1.205   1.00 32.24  ? 189 TYR B CE1 1 
ATOM   5083  C CE2 . TYR B 1 189 ? -6.622  -22.537 2.836   1.00 35.79  ? 189 TYR B CE2 1 
ATOM   5084  C CZ  . TYR B 1 189 ? -7.617  -21.810 2.213   1.00 32.72  ? 189 TYR B CZ  1 
ATOM   5085  O OH  . TYR B 1 189 ? -7.872  -20.563 2.704   1.00 40.23  ? 189 TYR B OH  1 
ATOM   5086  N N   . ILE B 1 190 ? -9.465  -27.287 0.276   1.00 24.65  ? 190 ILE B N   1 
ATOM   5087  C CA  . ILE B 1 190 ? -10.827 -27.379 -0.177  1.00 24.87  ? 190 ILE B CA  1 
ATOM   5088  C C   . ILE B 1 190 ? -11.686 -28.126 0.835   1.00 25.73  ? 190 ILE B C   1 
ATOM   5089  O O   . ILE B 1 190 ? -12.762 -27.667 1.202   1.00 24.24  ? 190 ILE B O   1 
ATOM   5090  C CB  . ILE B 1 190 ? -10.860 -28.045 -1.561  1.00 23.54  ? 190 ILE B CB  1 
ATOM   5091  C CG1 . ILE B 1 190 ? -10.248 -27.121 -2.617  1.00 23.91  ? 190 ILE B CG1 1 
ATOM   5092  C CG2 . ILE B 1 190 ? -12.286 -28.464 -1.895  1.00 26.07  ? 190 ILE B CG2 1 
ATOM   5093  C CD1 . ILE B 1 190 ? -9.899  -27.856 -3.903  1.00 26.82  ? 190 ILE B CD1 1 
ATOM   5094  N N   . TYR B 1 191 ? -11.196 -29.272 1.298   1.00 27.81  ? 191 TYR B N   1 
ATOM   5095  C CA  . TYR B 1 191 ? -11.952 -30.075 2.233   1.00 25.74  ? 191 TYR B CA  1 
ATOM   5096  C C   . TYR B 1 191 ? -12.238 -29.288 3.516   1.00 24.97  ? 191 TYR B C   1 
ATOM   5097  O O   . TYR B 1 191 ? -13.371 -29.274 4.032   1.00 25.52  ? 191 TYR B O   1 
ATOM   5098  C CB  . TYR B 1 191 ? -11.191 -31.391 2.470   1.00 28.31  ? 191 TYR B CB  1 
ATOM   5099  C CG  . TYR B 1 191 ? -11.969 -32.387 3.304   1.00 24.73  ? 191 TYR B CG  1 
ATOM   5100  C CD1 . TYR B 1 191 ? -13.014 -33.102 2.766   1.00 26.29  ? 191 TYR B CD1 1 
ATOM   5101  C CD2 . TYR B 1 191 ? -11.720 -32.535 4.657   1.00 25.85  ? 191 TYR B CD2 1 
ATOM   5102  C CE1 . TYR B 1 191 ? -13.735 -34.016 3.511   1.00 29.39  ? 191 TYR B CE1 1 
ATOM   5103  C CE2 . TYR B 1 191 ? -12.453 -33.416 5.431   1.00 30.23  ? 191 TYR B CE2 1 
ATOM   5104  C CZ  . TYR B 1 191 ? -13.463 -34.172 4.857   1.00 31.63  ? 191 TYR B CZ  1 
ATOM   5105  O OH  . TYR B 1 191 ? -14.225 -35.045 5.627   1.00 32.94  ? 191 TYR B OH  1 
ATOM   5106  N N   . ARG B 1 192 ? -11.197 -28.648 4.067   1.00 25.03  ? 192 ARG B N   1 
ATOM   5107  C CA  . ARG B 1 192 ? -11.338 -28.002 5.359   1.00 26.44  ? 192 ARG B CA  1 
ATOM   5108  C C   . ARG B 1 192 ? -12.224 -26.770 5.214   1.00 25.69  ? 192 ARG B C   1 
ATOM   5109  O O   . ARG B 1 192 ? -13.083 -26.517 6.052   1.00 26.03  ? 192 ARG B O   1 
ATOM   5110  C CB  . ARG B 1 192 ? -9.971  -27.585 5.917   1.00 23.65  ? 192 ARG B CB  1 
ATOM   5111  C CG  . ARG B 1 192 ? -9.018  -28.736 6.178   1.00 24.56  ? 192 ARG B CG  1 
ATOM   5112  C CD  . ARG B 1 192 ? -9.533  -29.688 7.236   1.00 25.78  ? 192 ARG B CD  1 
ATOM   5113  N NE  . ARG B 1 192 ? -9.618  -29.020 8.521   1.00 24.88  ? 192 ARG B NE  1 
ATOM   5114  C CZ  . ARG B 1 192 ? -10.037 -29.611 9.613   1.00 27.24  ? 192 ARG B CZ  1 
ATOM   5115  N NH1 . ARG B 1 192 ? -10.339 -30.893 9.587   1.00 29.96  ? 192 ARG B NH1 1 
ATOM   5116  N NH2 . ARG B 1 192 ? -10.162 -28.929 10.730  1.00 28.12  ? 192 ARG B NH2 1 
ATOM   5117  N N   . ARG B 1 193 ? -12.031 -26.014 4.138   1.00 25.10  ? 193 ARG B N   1 
ATOM   5118  C CA  . ARG B 1 193 ? -12.825 -24.811 3.955   1.00 23.96  ? 193 ARG B CA  1 
ATOM   5119  C C   . ARG B 1 193 ? -14.306 -25.148 3.765   1.00 26.51  ? 193 ARG B C   1 
ATOM   5120  O O   . ARG B 1 193 ? -15.163 -24.490 4.341   1.00 29.71  ? 193 ARG B O   1 
ATOM   5121  C CB  . ARG B 1 193 ? -12.319 -23.975 2.778   1.00 24.91  ? 193 ARG B CB  1 
ATOM   5122  C CG  . ARG B 1 193 ? -13.063 -22.647 2.660   1.00 26.35  ? 193 ARG B CG  1 
ATOM   5123  C CD  . ARG B 1 193 ? -12.683 -21.819 1.469   1.00 28.56  ? 193 ARG B CD  1 
ATOM   5124  N NE  . ARG B 1 193 ? -13.409 -20.541 1.432   1.00 30.40  ? 193 ARG B NE  1 
ATOM   5125  C CZ  . ARG B 1 193 ? -13.895 -20.045 0.309   1.00 27.59  ? 193 ARG B CZ  1 
ATOM   5126  N NH1 . ARG B 1 193 ? -13.648 -20.686 -0.811  1.00 25.88  ? 193 ARG B NH1 1 
ATOM   5127  N NH2 . ARG B 1 193 ? -14.584 -18.922 0.300   1.00 34.97  ? 193 ARG B NH2 1 
ATOM   5128  N N   . LYS B 1 194 ? -14.633 -26.107 2.896   1.00 28.12  ? 194 LYS B N   1 
ATOM   5129  C CA  . LYS B 1 194 ? -16.025 -26.447 2.620   1.00 27.80  ? 194 LYS B CA  1 
ATOM   5130  C C   . LYS B 1 194 ? -16.671 -27.191 3.794   1.00 28.57  ? 194 LYS B C   1 
ATOM   5131  O O   . LYS B 1 194 ? -17.767 -26.832 4.229   1.00 28.36  ? 194 LYS B O   1 
ATOM   5132  C CB  . LYS B 1 194 ? -16.151 -27.313 1.366   1.00 28.40  ? 194 LYS B CB  1 
ATOM   5133  C CG  . LYS B 1 194 ? -15.972 -26.594 0.043   1.00 29.03  ? 194 LYS B CG  1 
ATOM   5134  C CD  . LYS B 1 194 ? -16.241 -27.510 -1.164  1.00 28.91  ? 194 LYS B CD  1 
ATOM   5135  C CE  . LYS B 1 194 ? -17.714 -27.803 -1.367  1.00 29.87  ? 194 LYS B CE  1 
ATOM   5136  N NZ  . LYS B 1 194 ? -18.426 -26.646 -1.952  1.00 28.33  ? 194 LYS B NZ  1 
ATOM   5137  N N   . TYR B 1 195 ? -15.977 -28.138 4.421   1.00 29.68  ? 195 TYR B N   1 
ATOM   5138  C CA  . TYR B 1 195 ? -16.692 -29.114 5.242   1.00 30.37  ? 195 TYR B CA  1 
ATOM   5139  C C   . TYR B 1 195 ? -16.253 -29.135 6.704   1.00 31.63  ? 195 TYR B C   1 
ATOM   5140  O O   . TYR B 1 195 ? -17.008 -29.638 7.519   1.00 31.46  ? 195 TYR B O   1 
ATOM   5141  C CB  . TYR B 1 195 ? -16.570 -30.528 4.656   1.00 31.69  ? 195 TYR B CB  1 
ATOM   5142  C CG  . TYR B 1 195 ? -16.880 -30.634 3.179   1.00 29.18  ? 195 TYR B CG  1 
ATOM   5143  C CD1 . TYR B 1 195 ? -18.160 -30.431 2.683   1.00 32.30  ? 195 TYR B CD1 1 
ATOM   5144  C CD2 . TYR B 1 195 ? -15.907 -31.002 2.292   1.00 28.53  ? 195 TYR B CD2 1 
ATOM   5145  C CE1 . TYR B 1 195 ? -18.449 -30.600 1.341   1.00 32.00  ? 195 TYR B CE1 1 
ATOM   5146  C CE2 . TYR B 1 195 ? -16.164 -31.150 0.940   1.00 30.57  ? 195 TYR B CE2 1 
ATOM   5147  C CZ  . TYR B 1 195 ? -17.443 -30.986 0.469   1.00 31.29  ? 195 TYR B CZ  1 
ATOM   5148  O OH  . TYR B 1 195 ? -17.626 -31.127 -0.877  1.00 34.33  ? 195 TYR B OH  1 
ATOM   5149  N N   . LYS B 1 196 ? -15.115 -28.545 7.088   1.00 30.07  ? 196 LYS B N   1 
ATOM   5150  C CA  . LYS B 1 196 ? -14.675 -28.648 8.481   1.00 30.05  ? 196 LYS B CA  1 
ATOM   5151  C C   . LYS B 1 196 ? -14.426 -27.284 9.105   1.00 33.17  ? 196 LYS B C   1 
ATOM   5152  O O   . LYS B 1 196 ? -13.471 -27.107 9.859   1.00 35.27  ? 196 LYS B O   1 
ATOM   5153  C CB  . LYS B 1 196 ? -13.393 -29.473 8.566   1.00 28.44  ? 196 LYS B CB  1 
ATOM   5154  C CG  . LYS B 1 196 ? -13.544 -30.893 8.020   1.00 34.19  ? 196 LYS B CG  1 
ATOM   5155  C CD  . LYS B 1 196 ? -14.440 -31.772 8.902   1.00 37.17  ? 196 LYS B CD  1 
ATOM   5156  C CE  . LYS B 1 196 ? -14.543 -33.167 8.348   1.00 42.44  ? 196 LYS B CE  1 
ATOM   5157  N NZ  . LYS B 1 196 ? -15.434 -33.998 9.169   1.00 46.10  ? 196 LYS B NZ  1 
ATOM   5158  N N   . GLY B 1 197 ? -15.278 -26.320 8.767   1.00 29.14  ? 197 GLY B N   1 
ATOM   5159  C CA  . GLY B 1 197 ? -15.287 -25.045 9.447   1.00 29.06  ? 197 GLY B CA  1 
ATOM   5160  C C   . GLY B 1 197 ? -14.083 -24.164 9.135   1.00 27.09  ? 197 GLY B C   1 
ATOM   5161  O O   . GLY B 1 197 ? -13.791 -23.290 9.933   1.00 29.49  ? 197 GLY B O   1 
ATOM   5162  N N   . ASP B 1 198 ? -13.403 -24.371 7.989   1.00 23.20  ? 198 ASP B N   1 
ATOM   5163  C CA  . ASP B 1 198 ? -12.401 -23.441 7.501   1.00 25.63  ? 198 ASP B CA  1 
ATOM   5164  C C   . ASP B 1 198 ? -11.274 -23.241 8.520   1.00 28.02  ? 198 ASP B C   1 
ATOM   5165  O O   . ASP B 1 198 ? -10.780 -22.127 8.700   1.00 26.34  ? 198 ASP B O   1 
ATOM   5166  C CB  . ASP B 1 198 ? -13.066 -22.087 7.183   1.00 27.05  ? 198 ASP B CB  1 
ATOM   5167  C CG  . ASP B 1 198 ? -12.277 -21.121 6.306   1.00 30.22  ? 198 ASP B CG  1 
ATOM   5168  O OD1 . ASP B 1 198 ? -11.358 -21.603 5.591   1.00 27.68  ? 198 ASP B OD1 1 
ATOM   5169  O OD2 . ASP B 1 198 ? -12.643 -19.876 6.291   1.00 28.13  ? 198 ASP B OD2 1 
ATOM   5170  N N   . THR B 1 199 ? -10.872 -24.327 9.179   1.00 29.29  ? 199 THR B N   1 
ATOM   5171  C CA  . THR B 1 199 ? -9.671  -24.413 9.995   1.00 33.78  ? 199 THR B CA  1 
ATOM   5172  C C   . THR B 1 199 ? -8.642  -25.229 9.230   1.00 34.24  ? 199 THR B C   1 
ATOM   5173  O O   . THR B 1 199 ? -9.019  -26.237 8.663   1.00 28.35  ? 199 THR B O   1 
ATOM   5174  C CB  . THR B 1 199 ? -10.042 -25.132 11.301  1.00 41.13  ? 199 THR B CB  1 
ATOM   5175  O OG1 . THR B 1 199 ? -10.767 -24.125 12.013  1.00 52.51  ? 199 THR B OG1 1 
ATOM   5176  C CG2 . THR B 1 199 ? -8.863  -25.620 12.103  1.00 62.87  ? 199 THR B CG2 1 
ATOM   5177  N N   . HIS B 1 200 ? -7.365  -24.844 9.229   1.00 31.18  ? 200 HIS B N   1 
ATOM   5178  C CA  . HIS B 1 200 ? -6.432  -25.436 8.291   1.00 34.15  ? 200 HIS B CA  1 
ATOM   5179  C C   . HIS B 1 200 ? -5.256  -26.069 9.028   1.00 37.16  ? 200 HIS B C   1 
ATOM   5180  O O   . HIS B 1 200 ? -4.712  -25.452 9.907   1.00 35.85  ? 200 HIS B O   1 
ATOM   5181  C CB  . HIS B 1 200 ? -6.015  -24.370 7.285   1.00 35.73  ? 200 HIS B CB  1 
ATOM   5182  C CG  . HIS B 1 200 ? -7.216  -23.932 6.537   1.00 35.74  ? 200 HIS B CG  1 
ATOM   5183  N ND1 . HIS B 1 200 ? -7.630  -24.647 5.439   1.00 28.57  ? 200 HIS B ND1 1 
ATOM   5184  C CD2 . HIS B 1 200 ? -8.112  -22.927 6.727   1.00 30.00  ? 200 HIS B CD2 1 
ATOM   5185  C CE1 . HIS B 1 200 ? -8.742  -24.083 4.952   1.00 27.27  ? 200 HIS B CE1 1 
ATOM   5186  N NE2 . HIS B 1 200 ? -9.050  -23.038 5.722   1.00 30.81  ? 200 HIS B NE2 1 
ATOM   5187  N N   . ILE B 1 201 ? -4.847  -27.265 8.602   1.00 33.68  ? 201 ILE B N   1 
ATOM   5188  C CA  . ILE B 1 201 ? -3.787  -28.053 9.217   1.00 35.29  ? 201 ILE B CA  1 
ATOM   5189  C C   . ILE B 1 201 ? -2.594  -28.126 8.259   1.00 38.73  ? 201 ILE B C   1 
ATOM   5190  O O   . ILE B 1 201 ? -2.744  -28.463 7.070   1.00 30.89  ? 201 ILE B O   1 
ATOM   5191  C CB  . ILE B 1 201 ? -4.337  -29.454 9.563   1.00 36.59  ? 201 ILE B CB  1 
ATOM   5192  C CG1 . ILE B 1 201 ? -5.543  -29.369 10.495  1.00 34.83  ? 201 ILE B CG1 1 
ATOM   5193  C CG2 . ILE B 1 201 ? -3.264  -30.358 10.140  1.00 38.44  ? 201 ILE B CG2 1 
ATOM   5194  C CD1 . ILE B 1 201 ? -6.469  -30.559 10.401  1.00 39.40  ? 201 ILE B CD1 1 
ATOM   5195  N N   . ALA B 1 202 ? -1.393  -27.832 8.781   1.00 33.76  ? 202 ALA B N   1 
ATOM   5196  C CA  . ALA B 1 202 ? -0.192  -27.810 7.951   1.00 38.05  ? 202 ALA B CA  1 
ATOM   5197  C C   . ALA B 1 202 ? 0.266   -29.237 7.639   1.00 30.96  ? 202 ALA B C   1 
ATOM   5198  O O   . ALA B 1 202 ? -0.073  -30.165 8.369   1.00 31.99  ? 202 ALA B O   1 
ATOM   5199  C CB  . ALA B 1 202 ? 0.922   -27.030 8.622   1.00 44.41  ? 202 ALA B CB  1 
ATOM   5200  N N   . PRO B 1 203 ? 0.994   -29.444 6.519   1.00 30.74  ? 203 PRO B N   1 
ATOM   5201  C CA  . PRO B 1 203 ? 1.644   -30.721 6.240   1.00 37.13  ? 203 PRO B CA  1 
ATOM   5202  C C   . PRO B 1 203 ? 2.574   -31.096 7.389   1.00 43.85  ? 203 PRO B C   1 
ATOM   5203  O O   . PRO B 1 203 ? 3.242   -30.244 7.982   1.00 37.44  ? 203 PRO B O   1 
ATOM   5204  C CB  . PRO B 1 203 ? 2.428   -30.544 4.925   1.00 35.19  ? 203 PRO B CB  1 
ATOM   5205  C CG  . PRO B 1 203 ? 2.247   -29.094 4.494   1.00 35.26  ? 203 PRO B CG  1 
ATOM   5206  C CD  . PRO B 1 203 ? 1.293   -28.433 5.484   1.00 35.59  ? 203 PRO B CD  1 
ATOM   5207  N N   . ASP B 1 204 ? 2.517   -32.372 7.757   1.00 43.14  ? 204 ASP B N   1 
ATOM   5208  C CA  . ASP B 1 204 ? 3.479   -32.941 8.680   1.00 47.69  ? 204 ASP B CA  1 
ATOM   5209  C C   . ASP B 1 204 ? 4.745   -33.354 7.914   1.00 44.77  ? 204 ASP B C   1 
ATOM   5210  O O   . ASP B 1 204 ? 4.713   -34.291 7.119   1.00 43.47  ? 204 ASP B O   1 
ATOM   5211  C CB  . ASP B 1 204 ? 2.826   -34.108 9.423   1.00 47.53  ? 204 ASP B CB  1 
ATOM   5212  C CG  . ASP B 1 204 ? 3.755   -34.802 10.404  1.00 53.29  ? 204 ASP B CG  1 
ATOM   5213  O OD1 . ASP B 1 204 ? 5.005   -34.605 10.294  1.00 48.63  ? 204 ASP B OD1 1 
ATOM   5214  O OD2 . ASP B 1 204 ? 3.219   -35.528 11.277  1.00 55.31  ? 204 ASP B OD2 1 
ATOM   5215  N N   . PRO B 1 205 ? 5.936   -32.769 8.176   1.00 46.70  ? 205 PRO B N   1 
ATOM   5216  C CA  . PRO B 1 205 ? 7.120   -33.128 7.389   1.00 46.85  ? 205 PRO B CA  1 
ATOM   5217  C C   . PRO B 1 205 ? 7.634   -34.551 7.680   1.00 49.43  ? 205 PRO B C   1 
ATOM   5218  O O   . PRO B 1 205 ? 8.562   -35.017 7.023   1.00 48.92  ? 205 PRO B O   1 
ATOM   5219  C CB  . PRO B 1 205 ? 8.144   -32.030 7.761   1.00 49.26  ? 205 PRO B CB  1 
ATOM   5220  C CG  . PRO B 1 205 ? 7.729   -31.582 9.168   1.00 52.01  ? 205 PRO B CG  1 
ATOM   5221  C CD  . PRO B 1 205 ? 6.229   -31.802 9.259   1.00 51.62  ? 205 PRO B CD  1 
ATOM   5222  N N   . ASN B 1 206 ? 7.016   -35.273 8.626   1.00 42.07  ? 206 ASN B N   1 
ATOM   5223  C CA  . ASN B 1 206 ? 7.437   -36.633 8.924   1.00 43.41  ? 206 ASN B CA  1 
ATOM   5224  C C   . ASN B 1 206 ? 6.436   -37.671 8.439   1.00 44.92  ? 206 ASN B C   1 
ATOM   5225  O O   . ASN B 1 206 ? 6.557   -38.836 8.802   1.00 45.67  ? 206 ASN B O   1 
ATOM   5226  C CB  . ASN B 1 206 ? 7.664   -36.851 10.422  1.00 51.42  ? 206 ASN B CB  1 
ATOM   5227  C CG  . ASN B 1 206 ? 8.738   -35.933 10.971  1.00 58.06  ? 206 ASN B CG  1 
ATOM   5228  O OD1 . ASN B 1 206 ? 9.802   -35.769 10.374  1.00 64.34  ? 206 ASN B OD1 1 
ATOM   5229  N ND2 . ASN B 1 206 ? 8.443   -35.281 12.079  1.00 65.27  ? 206 ASN B ND2 1 
ATOM   5230  N N   . LEU B 1 207 ? 5.460   -37.274 7.614   1.00 46.50  ? 207 LEU B N   1 
ATOM   5231  C CA  . LEU B 1 207 ? 4.574   -38.249 6.987   1.00 45.57  ? 207 LEU B CA  1 
ATOM   5232  C C   . LEU B 1 207 ? 4.855   -38.289 5.481   1.00 40.59  ? 207 LEU B C   1 
ATOM   5233  O O   . LEU B 1 207 ? 5.275   -37.310 4.853   1.00 43.39  ? 207 LEU B O   1 
ATOM   5234  C CB  . LEU B 1 207 ? 3.100   -37.922 7.257   1.00 46.10  ? 207 LEU B CB  1 
ATOM   5235  C CG  . LEU B 1 207 ? 2.582   -38.146 8.674   1.00 48.07  ? 207 LEU B CG  1 
ATOM   5236  C CD1 . LEU B 1 207 ? 1.263   -37.413 8.874   1.00 47.04  ? 207 LEU B CD1 1 
ATOM   5237  C CD2 . LEU B 1 207 ? 2.389   -39.621 8.960   1.00 46.75  ? 207 LEU B CD2 1 
ATOM   5238  N N   . ASP B 1 208 ? 4.620   -39.466 4.924   1.00 38.62  ? 208 ASP B N   1 
ATOM   5239  C CA  . ASP B 1 208 ? 4.637   -39.697 3.485   1.00 41.53  ? 208 ASP B CA  1 
ATOM   5240  C C   . ASP B 1 208 ? 3.469   -38.955 2.811   1.00 38.40  ? 208 ASP B C   1 
ATOM   5241  O O   . ASP B 1 208 ? 2.601   -38.406 3.483   1.00 34.35  ? 208 ASP B O   1 
ATOM   5242  C CB  . ASP B 1 208 ? 4.517   -41.207 3.240   1.00 38.09  ? 208 ASP B CB  1 
ATOM   5243  C CG  . ASP B 1 208 ? 3.333   -41.862 3.938   1.00 38.99  ? 208 ASP B CG  1 
ATOM   5244  O OD1 . ASP B 1 208 ? 3.443   -42.061 5.153   1.00 45.23  ? 208 ASP B OD1 1 
ATOM   5245  O OD2 . ASP B 1 208 ? 2.289   -42.170 3.269   1.00 40.01  ? 208 ASP B OD2 1 
ATOM   5246  N N   . TRP B 1 209 ? 3.398   -39.018 1.475   1.00 36.92  ? 209 TRP B N   1 
ATOM   5247  C CA  . TRP B 1 209 ? 2.462   -38.229 0.677   1.00 35.46  ? 209 TRP B CA  1 
ATOM   5248  C C   . TRP B 1 209 ? 1.000   -38.538 0.985   1.00 31.66  ? 209 TRP B C   1 
ATOM   5249  O O   . TRP B 1 209 ? 0.205   -37.637 1.240   1.00 34.25  ? 209 TRP B O   1 
ATOM   5250  C CB  . TRP B 1 209 ? 2.806   -38.455 -0.785  1.00 37.36  ? 209 TRP B CB  1 
ATOM   5251  C CG  . TRP B 1 209 ? 2.050   -37.676 -1.808  1.00 32.55  ? 209 TRP B CG  1 
ATOM   5252  C CD1 . TRP B 1 209 ? 2.261   -36.388 -2.181  1.00 29.76  ? 209 TRP B CD1 1 
ATOM   5253  C CD2 . TRP B 1 209 ? 1.095   -38.217 -2.737  1.00 33.53  ? 209 TRP B CD2 1 
ATOM   5254  N NE1 . TRP B 1 209 ? 1.477   -36.077 -3.258  1.00 29.67  ? 209 TRP B NE1 1 
ATOM   5255  C CE2 . TRP B 1 209 ? 0.727   -37.165 -3.609  1.00 31.19  ? 209 TRP B CE2 1 
ATOM   5256  C CE3 . TRP B 1 209 ? 0.464   -39.462 -2.875  1.00 30.25  ? 209 TRP B CE3 1 
ATOM   5257  C CZ2 . TRP B 1 209 ? -0.199  -37.339 -4.646  1.00 29.82  ? 209 TRP B CZ2 1 
ATOM   5258  C CZ3 . TRP B 1 209 ? -0.486  -39.620 -3.861  1.00 31.63  ? 209 TRP B CZ3 1 
ATOM   5259  C CH2 . TRP B 1 209 ? -0.788  -38.584 -4.756  1.00 30.58  ? 209 TRP B CH2 1 
ATOM   5260  N N   . SER B 1 210 ? 0.618   -39.802 1.002   1.00 33.14  ? 210 SER B N   1 
ATOM   5261  C CA  . SER B 1 210 ? -0.782  -40.176 1.198   1.00 32.67  ? 210 SER B CA  1 
ATOM   5262  C C   . SER B 1 210 ? -1.273  -39.852 2.598   1.00 39.33  ? 210 SER B C   1 
ATOM   5263  O O   . SER B 1 210 ? -2.449  -39.492 2.829   1.00 35.94  ? 210 SER B O   1 
ATOM   5264  C CB  . SER B 1 210 ? -1.007  -41.650 0.984   1.00 43.06  ? 210 SER B CB  1 
ATOM   5265  O OG  . SER B 1 210 ? -0.405  -42.068 -0.215  1.00 40.07  ? 210 SER B OG  1 
ATOM   5266  N N   . ALA B 1 211 ? -0.391  -40.126 3.546   1.00 36.64  ? 211 ALA B N   1 
ATOM   5267  C CA  . ALA B 1 211 ? -0.736  -39.940 4.943   1.00 40.09  ? 211 ALA B CA  1 
ATOM   5268  C C   . ALA B 1 211 ? -0.929  -38.455 5.243   1.00 31.08  ? 211 ALA B C   1 
ATOM   5269  O O   . ALA B 1 211 ? -1.761  -38.115 6.046   1.00 32.31  ? 211 ALA B O   1 
ATOM   5270  C CB  . ALA B 1 211 ? 0.333   -40.554 5.813   1.00 40.57  ? 211 ALA B CB  1 
ATOM   5271  N N   . ASN B 1 212 ? -0.099  -37.607 4.647   1.00 34.62  ? 212 ASN B N   1 
ATOM   5272  C CA  . ASN B 1 212 ? -0.212  -36.174 4.788   1.00 33.82  ? 212 ASN B CA  1 
ATOM   5273  C C   . ASN B 1 212 ? -1.567  -35.660 4.291   1.00 34.33  ? 212 ASN B C   1 
ATOM   5274  O O   . ASN B 1 212 ? -2.138  -34.750 4.899   1.00 33.02  ? 212 ASN B O   1 
ATOM   5275  C CB  . ASN B 1 212 ? 0.933   -35.456 4.088   1.00 36.02  ? 212 ASN B CB  1 
ATOM   5276  C CG  . ASN B 1 212 ? 1.842   -34.741 5.058   1.00 37.94  ? 212 ASN B CG  1 
ATOM   5277  O OD1 . ASN B 1 212 ? 1.381   -34.165 6.032   1.00 37.30  ? 212 ASN B OD1 1 
ATOM   5278  N ND2 . ASN B 1 212 ? 3.132   -34.762 4.791   1.00 42.72  ? 212 ASN B ND2 1 
ATOM   5279  N N   . LEU B 1 213 ? -2.130  -36.254 3.225   1.00 31.68  ? 213 LEU B N   1 
ATOM   5280  C CA  . LEU B 1 213 ? -3.470  -35.859 2.813   1.00 35.92  ? 213 LEU B CA  1 
ATOM   5281  C C   . LEU B 1 213 ? -4.467  -36.151 3.934   1.00 31.05  ? 213 LEU B C   1 
ATOM   5282  O O   . LEU B 1 213 ? -5.282  -35.309 4.309   1.00 28.42  ? 213 LEU B O   1 
ATOM   5283  C CB  . LEU B 1 213 ? -3.890  -36.541 1.505   1.00 34.06  ? 213 LEU B CB  1 
ATOM   5284  C CG  . LEU B 1 213 ? -5.314  -36.194 1.049   1.00 37.27  ? 213 LEU B CG  1 
ATOM   5285  C CD1 . LEU B 1 213 ? -5.540  -34.685 0.995   1.00 35.84  ? 213 LEU B CD1 1 
ATOM   5286  C CD2 . LEU B 1 213 ? -5.617  -36.804 -0.320  1.00 37.08  ? 213 LEU B CD2 1 
ATOM   5287  N N   . ALA B 1 214 ? -4.434  -37.358 4.477   1.00 30.61  ? 214 ALA B N   1 
ATOM   5288  C CA  . ALA B 1 214 ? -5.370  -37.696 5.540   1.00 30.20  ? 214 ALA B CA  1 
ATOM   5289  C C   . ALA B 1 214 ? -5.181  -36.764 6.746   1.00 31.52  ? 214 ALA B C   1 
ATOM   5290  O O   . ALA B 1 214 ? -6.154  -36.308 7.361   1.00 30.86  ? 214 ALA B O   1 
ATOM   5291  C CB  . ALA B 1 214 ? -5.165  -39.137 5.950   1.00 35.24  ? 214 ALA B CB  1 
ATOM   5292  N N   . HIS B 1 215 ? -3.919  -36.502 7.089   1.00 32.74  ? 215 HIS B N   1 
ATOM   5293  C CA  . HIS B 1 215 ? -3.579  -35.638 8.212   1.00 32.50  ? 215 HIS B CA  1 
ATOM   5294  C C   . HIS B 1 215 ? -4.219  -34.265 7.979   1.00 31.15  ? 215 HIS B C   1 
ATOM   5295  O O   . HIS B 1 215 ? -4.890  -33.734 8.850   1.00 32.38  ? 215 HIS B O   1 
ATOM   5296  C CB  . HIS B 1 215 ? -2.057  -35.560 8.379   1.00 29.71  ? 215 HIS B CB  1 
ATOM   5297  C CG  . HIS B 1 215 ? -1.582  -34.619 9.443   1.00 29.28  ? 215 HIS B CG  1 
ATOM   5298  N ND1 . HIS B 1 215 ? -1.942  -34.725 10.771  1.00 36.22  ? 215 HIS B ND1 1 
ATOM   5299  C CD2 . HIS B 1 215 ? -0.839  -33.514 9.354   1.00 33.72  ? 215 HIS B CD2 1 
ATOM   5300  C CE1 . HIS B 1 215 ? -1.406  -33.725 11.455  1.00 32.22  ? 215 HIS B CE1 1 
ATOM   5301  N NE2 . HIS B 1 215 ? -0.708  -32.990 10.631  1.00 37.25  ? 215 HIS B NE2 1 
ATOM   5302  N N   . MET B 1 216 ? -4.030  -33.715 6.786   1.00 29.48  ? 216 MET B N   1 
ATOM   5303  C CA  . MET B 1 216 ? -4.407  -32.333 6.527   1.00 26.96  ? 216 MET B CA  1 
ATOM   5304  C C   . MET B 1 216 ? -5.927  -32.198 6.404   1.00 29.62  ? 216 MET B C   1 
ATOM   5305  O O   . MET B 1 216 ? -6.482  -31.126 6.628   1.00 29.85  ? 216 MET B O   1 
ATOM   5306  C CB  . MET B 1 216 ? -3.706  -31.798 5.286   1.00 30.22  ? 216 MET B CB  1 
ATOM   5307  C CG  . MET B 1 216 ? -2.247  -31.516 5.506   1.00 27.61  ? 216 MET B CG  1 
ATOM   5308  S SD  . MET B 1 216 ? -1.394  -30.833 4.088   1.00 33.81  ? 216 MET B SD  1 
ATOM   5309  C CE  . MET B 1 216 ? -1.537  -32.140 2.870   1.00 35.01  ? 216 MET B CE  1 
ATOM   5310  N N   . MET B 1 217 ? -6.611  -33.309 6.136   1.00 25.47  ? 217 MET B N   1 
ATOM   5311  C CA  . MET B 1 217 ? -8.045  -33.314 6.101   1.00 28.75  ? 217 MET B CA  1 
ATOM   5312  C C   . MET B 1 217 ? -8.597  -33.441 7.512   1.00 28.25  ? 217 MET B C   1 
ATOM   5313  O O   . MET B 1 217 ? -9.773  -33.188 7.709   1.00 28.01  ? 217 MET B O   1 
ATOM   5314  C CB  . MET B 1 217 ? -8.566  -34.477 5.258   1.00 27.41  ? 217 MET B CB  1 
ATOM   5315  C CG  . MET B 1 217 ? -8.533  -34.192 3.796   1.00 30.22  ? 217 MET B CG  1 
ATOM   5316  S SD  . MET B 1 217 ? -8.794  -35.708 2.795   1.00 30.54  ? 217 MET B SD  1 
ATOM   5317  C CE  . MET B 1 217 ? -10.462 -36.072 3.286   1.00 28.83  ? 217 MET B CE  1 
ATOM   5318  N N   . GLY B 1 218 ? -7.766  -33.890 8.456   1.00 31.43  ? 218 GLY B N   1 
ATOM   5319  C CA  . GLY B 1 218 ? -8.136  -33.968 9.867   1.00 30.49  ? 218 GLY B CA  1 
ATOM   5320  C C   . GLY B 1 218 ? -8.340  -35.401 10.366  1.00 33.67  ? 218 GLY B C   1 
ATOM   5321  O O   . GLY B 1 218 ? -9.056  -35.567 11.318  1.00 32.17  ? 218 GLY B O   1 
ATOM   5322  N N   . PHE B 1 219 ? -7.717  -36.410 9.729   1.00 32.91  ? 219 PHE B N   1 
ATOM   5323  C CA  . PHE B 1 219 ? -7.939  -37.823 10.025  1.00 34.76  ? 219 PHE B CA  1 
ATOM   5324  C C   . PHE B 1 219 ? -6.608  -38.429 10.433  1.00 34.41  ? 219 PHE B C   1 
ATOM   5325  O O   . PHE B 1 219 ? -5.786  -38.705 9.585   1.00 43.78  ? 219 PHE B O   1 
ATOM   5326  C CB  . PHE B 1 219 ? -8.487  -38.588 8.817   1.00 33.47  ? 219 PHE B CB  1 
ATOM   5327  C CG  . PHE B 1 219 ? -9.877  -38.177 8.466   1.00 36.25  ? 219 PHE B CG  1 
ATOM   5328  C CD1 . PHE B 1 219 ? -10.958 -38.678 9.165   1.00 35.57  ? 219 PHE B CD1 1 
ATOM   5329  C CD2 . PHE B 1 219 ? -10.086 -37.160 7.548   1.00 39.86  ? 219 PHE B CD2 1 
ATOM   5330  C CE1 . PHE B 1 219 ? -12.236 -38.244 8.874   1.00 39.38  ? 219 PHE B CE1 1 
ATOM   5331  C CE2 . PHE B 1 219 ? -11.363 -36.700 7.286   1.00 37.30  ? 219 PHE B CE2 1 
ATOM   5332  C CZ  . PHE B 1 219 ? -12.434 -37.237 7.944   1.00 39.04  ? 219 PHE B CZ  1 
ATOM   5333  N N   . ASP B 1 220 ? -6.364  -38.486 11.741  1.00 41.75  ? 220 ASP B N   1 
ATOM   5334  C CA  . ASP B 1 220 ? -5.104  -38.965 12.268  1.00 39.84  ? 220 ASP B CA  1 
ATOM   5335  C C   . ASP B 1 220 ? -5.454  -40.292 12.897  1.00 43.11  ? 220 ASP B C   1 
ATOM   5336  O O   . ASP B 1 220 ? -5.955  -40.364 14.020  1.00 45.09  ? 220 ASP B O   1 
ATOM   5337  C CB  . ASP B 1 220 ? -4.421  -37.992 13.227  1.00 42.47  ? 220 ASP B CB  1 
ATOM   5338  C CG  . ASP B 1 220 ? -3.894  -36.756 12.532  1.00 46.49  ? 220 ASP B CG  1 
ATOM   5339  O OD1 . ASP B 1 220 ? -3.213  -36.889 11.487  1.00 46.50  ? 220 ASP B OD1 1 
ATOM   5340  O OD2 . ASP B 1 220 ? -4.132  -35.673 13.055  1.00 55.01  ? 220 ASP B OD2 1 
ATOM   5341  N N   . ASP B 1 221 ? -5.252  -41.313 12.069  1.00 42.69  ? 221 ASP B N   1 
ATOM   5342  C CA  . ASP B 1 221 ? -5.444  -42.689 12.447  1.00 46.28  ? 221 ASP B CA  1 
ATOM   5343  C C   . ASP B 1 221 ? -4.546  -43.556 11.550  1.00 52.60  ? 221 ASP B C   1 
ATOM   5344  O O   . ASP B 1 221 ? -4.503  -43.372 10.321  1.00 43.60  ? 221 ASP B O   1 
ATOM   5345  C CB  . ASP B 1 221 ? -6.934  -42.951 12.358  1.00 45.20  ? 221 ASP B CB  1 
ATOM   5346  C CG  . ASP B 1 221 ? -7.225  -44.416 12.509  1.00 52.30  ? 221 ASP B CG  1 
ATOM   5347  O OD1 . ASP B 1 221 ? -6.231  -45.180 12.468  1.00 50.38  ? 221 ASP B OD1 1 
ATOM   5348  O OD2 . ASP B 1 221 ? -8.427  -44.759 12.673  1.00 58.81  ? 221 ASP B OD2 1 
ATOM   5349  N N   . PHE B 1 222 ? -3.797  -44.495 12.152  1.00 42.77  ? 222 PHE B N   1 
ATOM   5350  C CA  . PHE B 1 222 ? -2.887  -45.323 11.366  1.00 42.20  ? 222 PHE B CA  1 
ATOM   5351  C C   . PHE B 1 222 ? -3.643  -46.069 10.260  1.00 37.68  ? 222 PHE B C   1 
ATOM   5352  O O   . PHE B 1 222 ? -3.110  -46.243 9.173   1.00 39.45  ? 222 PHE B O   1 
ATOM   5353  C CB  . PHE B 1 222 ? -2.093  -46.324 12.216  1.00 49.30  ? 222 PHE B CB  1 
ATOM   5354  C CG  . PHE B 1 222 ? -1.016  -47.070 11.451  1.00 53.38  ? 222 PHE B CG  1 
ATOM   5355  C CD1 . PHE B 1 222 ? 0.108   -46.412 10.964  1.00 49.52  ? 222 PHE B CD1 1 
ATOM   5356  C CD2 . PHE B 1 222 ? -1.150  -48.430 11.181  1.00 58.47  ? 222 PHE B CD2 1 
ATOM   5357  C CE1 . PHE B 1 222 ? 1.085   -47.096 10.253  1.00 53.02  ? 222 PHE B CE1 1 
ATOM   5358  C CE2 . PHE B 1 222 ? -0.165  -49.114 10.481  1.00 53.81  ? 222 PHE B CE2 1 
ATOM   5359  C CZ  . PHE B 1 222 ? 0.950   -48.449 10.025  1.00 50.69  ? 222 PHE B CZ  1 
ATOM   5360  N N   . GLU B 1 223 ? -4.855  -46.541 10.552  1.00 38.44  ? 223 GLU B N   1 
ATOM   5361  C CA  . GLU B 1 223 ? -5.668  -47.271 9.592   1.00 39.25  ? 223 GLU B CA  1 
ATOM   5362  C C   . GLU B 1 223 ? -6.041  -46.384 8.406   1.00 42.85  ? 223 GLU B C   1 
ATOM   5363  O O   . GLU B 1 223 ? -6.032  -46.845 7.262   1.00 39.70  ? 223 GLU B O   1 
ATOM   5364  C CB  . GLU B 1 223 ? -6.915  -47.824 10.287  1.00 40.73  ? 223 GLU B CB  1 
ATOM   5365  C CG  . GLU B 1 223 ? -6.599  -49.054 11.136  1.00 53.99  ? 223 GLU B CG  1 
ATOM   5366  C CD  . GLU B 1 223 ? -7.773  -49.921 11.597  1.00 54.91  ? 223 GLU B CD  1 
ATOM   5367  O OE1 . GLU B 1 223 ? -7.496  -50.951 12.248  1.00 67.18  ? 223 GLU B OE1 1 
ATOM   5368  O OE2 . GLU B 1 223 ? -8.964  -49.593 11.294  1.00 50.27  ? 223 GLU B OE2 1 
ATOM   5369  N N   . VAL B 1 224 ? -6.354  -45.111 8.693   1.00 39.31  ? 224 VAL B N   1 
ATOM   5370  C CA  . VAL B 1 224 ? -6.719  -44.170 7.662   1.00 35.08  ? 224 VAL B CA  1 
ATOM   5371  C C   . VAL B 1 224 ? -5.484  -43.930 6.805   1.00 34.76  ? 224 VAL B C   1 
ATOM   5372  O O   . VAL B 1 224 ? -5.603  -43.944 5.574   1.00 35.22  ? 224 VAL B O   1 
ATOM   5373  C CB  . VAL B 1 224 ? -7.347  -42.878 8.233   1.00 39.51  ? 224 VAL B CB  1 
ATOM   5374  C CG1 . VAL B 1 224 ? -7.645  -41.864 7.135   1.00 41.18  ? 224 VAL B CG1 1 
ATOM   5375  C CG2 . VAL B 1 224 ? -8.629  -43.178 8.994   1.00 38.54  ? 224 VAL B CG2 1 
ATOM   5376  N N   . TYR B 1 225 ? -4.305  -43.783 7.428   1.00 28.34  ? 225 TYR B N   1 
ATOM   5377  C CA  . TYR B 1 225 ? -3.102  -43.577 6.644   1.00 35.08  ? 225 TYR B CA  1 
ATOM   5378  C C   . TYR B 1 225 ? -2.907  -44.755 5.689   1.00 39.96  ? 225 TYR B C   1 
ATOM   5379  O O   . TYR B 1 225 ? -2.604  -44.553 4.504   1.00 36.82  ? 225 TYR B O   1 
ATOM   5380  C CB  . TYR B 1 225 ? -1.848  -43.359 7.495   1.00 38.61  ? 225 TYR B CB  1 
ATOM   5381  C CG  . TYR B 1 225 ? -1.811  -42.141 8.387   1.00 39.54  ? 225 TYR B CG  1 
ATOM   5382  C CD1 . TYR B 1 225 ? -2.746  -41.117 8.314   1.00 39.85  ? 225 TYR B CD1 1 
ATOM   5383  C CD2 . TYR B 1 225 ? -0.842  -42.068 9.372   1.00 42.52  ? 225 TYR B CD2 1 
ATOM   5384  C CE1 . TYR B 1 225 ? -2.684  -40.027 9.170   1.00 40.42  ? 225 TYR B CE1 1 
ATOM   5385  C CE2 . TYR B 1 225 ? -0.774  -41.001 10.240  1.00 44.47  ? 225 TYR B CE2 1 
ATOM   5386  C CZ  . TYR B 1 225 ? -1.711  -39.993 10.156  1.00 43.57  ? 225 TYR B CZ  1 
ATOM   5387  O OH  . TYR B 1 225 ? -1.562  -38.969 11.042  1.00 40.69  ? 225 TYR B OH  1 
ATOM   5388  N N   . GLU B 1 226 ? -3.085  -45.975 6.206   1.00 36.14  ? 226 GLU B N   1 
ATOM   5389  C CA  . GLU B 1 226 ? -2.915  -47.172 5.388   1.00 37.84  ? 226 GLU B CA  1 
ATOM   5390  C C   . GLU B 1 226 ? -3.975  -47.217 4.284   1.00 38.76  ? 226 GLU B C   1 
ATOM   5391  O O   . GLU B 1 226 ? -3.666  -47.531 3.143   1.00 32.90  ? 226 GLU B O   1 
ATOM   5392  C CB  . GLU B 1 226 ? -2.933  -48.411 6.286   1.00 41.55  ? 226 GLU B CB  1 
ATOM   5393  C CG  . GLU B 1 226 ? -1.631  -48.554 7.043   1.00 42.41  ? 226 GLU B CG  1 
ATOM   5394  C CD  . GLU B 1 226 ? -0.517  -49.120 6.183   1.00 47.00  ? 226 GLU B CD  1 
ATOM   5395  O OE1 . GLU B 1 226 ? 0.415   -48.358 5.764   1.00 46.49  ? 226 GLU B OE1 1 
ATOM   5396  O OE2 . GLU B 1 226 ? -0.568  -50.340 5.956   1.00 47.71  ? 226 GLU B OE2 1 
ATOM   5397  N N   . LEU B 1 227 ? -5.230  -46.897 4.598   1.00 35.18  ? 227 LEU B N   1 
ATOM   5398  C CA  . LEU B 1 227 ? -6.230  -46.873 3.559   1.00 35.41  ? 227 LEU B CA  1 
ATOM   5399  C C   . LEU B 1 227 ? -5.816  -45.904 2.435   1.00 41.07  ? 227 LEU B C   1 
ATOM   5400  O O   . LEU B 1 227 ? -5.947  -46.232 1.259   1.00 35.26  ? 227 LEU B O   1 
ATOM   5401  C CB  . LEU B 1 227 ? -7.576  -46.462 4.154   1.00 33.85  ? 227 LEU B CB  1 
ATOM   5402  C CG  . LEU B 1 227 ? -8.623  -46.051 3.121   1.00 33.36  ? 227 LEU B CG  1 
ATOM   5403  C CD1 . LEU B 1 227 ? -8.970  -47.186 2.176   1.00 39.93  ? 227 LEU B CD1 1 
ATOM   5404  C CD2 . LEU B 1 227 ? -9.872  -45.554 3.813   1.00 33.46  ? 227 LEU B CD2 1 
ATOM   5405  N N   . PHE B 1 228 ? -5.346  -44.704 2.784   1.00 35.07  ? 228 PHE B N   1 
ATOM   5406  C CA  . PHE B 1 228 ? -5.060  -43.663 1.801   1.00 35.28  ? 228 PHE B CA  1 
ATOM   5407  C C   . PHE B 1 228 ? -3.876  -44.091 0.929   1.00 33.58  ? 228 PHE B C   1 
ATOM   5408  O O   . PHE B 1 228 ? -3.856  -43.856 -0.288  1.00 31.20  ? 228 PHE B O   1 
ATOM   5409  C CB  . PHE B 1 228 ? -4.802  -42.306 2.496   1.00 35.66  ? 228 PHE B CB  1 
ATOM   5410  C CG  . PHE B 1 228 ? -6.003  -41.413 2.723   1.00 34.81  ? 228 PHE B CG  1 
ATOM   5411  C CD1 . PHE B 1 228 ? -7.145  -41.893 3.316   1.00 33.11  ? 228 PHE B CD1 1 
ATOM   5412  C CD2 . PHE B 1 228 ? -5.979  -40.069 2.376   1.00 33.33  ? 228 PHE B CD2 1 
ATOM   5413  C CE1 . PHE B 1 228 ? -8.246  -41.081 3.526   1.00 40.33  ? 228 PHE B CE1 1 
ATOM   5414  C CE2 . PHE B 1 228 ? -7.078  -39.257 2.602   1.00 31.97  ? 228 PHE B CE2 1 
ATOM   5415  C CZ  . PHE B 1 228 ? -8.210  -39.749 3.176   1.00 32.31  ? 228 PHE B CZ  1 
ATOM   5416  N N   . ARG B 1 229 ? -2.885  -44.757 1.535   1.00 33.25  ? 229 ARG B N   1 
ATOM   5417  C CA  . ARG B 1 229 ? -1.756  -45.299 0.784   1.00 35.91  ? 229 ARG B CA  1 
ATOM   5418  C C   . ARG B 1 229 ? -2.248  -46.305 -0.252  1.00 35.85  ? 229 ARG B C   1 
ATOM   5419  O O   . ARG B 1 229 ? -1.807  -46.258 -1.408  1.00 33.04  ? 229 ARG B O   1 
ATOM   5420  C CB  . ARG B 1 229 ? -0.701  -45.957 1.688   1.00 33.76  ? 229 ARG B CB  1 
ATOM   5421  C CG  . ARG B 1 229 ? 0.102   -44.978 2.535   1.00 34.78  ? 229 ARG B CG  1 
ATOM   5422  C CD  . ARG B 1 229 ? 0.580   -45.606 3.829   1.00 37.42  ? 229 ARG B CD  1 
ATOM   5423  N NE  . ARG B 1 229 ? 1.377   -44.657 4.594   1.00 42.41  ? 229 ARG B NE  1 
ATOM   5424  C CZ  . ARG B 1 229 ? 1.408   -44.586 5.930   1.00 40.29  ? 229 ARG B CZ  1 
ATOM   5425  N NH1 . ARG B 1 229 ? 0.787   -45.482 6.676   1.00 41.78  ? 229 ARG B NH1 1 
ATOM   5426  N NH2 . ARG B 1 229 ? 2.074   -43.608 6.518   1.00 35.29  ? 229 ARG B NH2 1 
ATOM   5427  N N   . LEU B 1 230 ? -3.175  -47.175 0.164   1.00 36.70  ? 230 LEU B N   1 
ATOM   5428  C CA  . LEU B 1 230 ? -3.657  -48.229 -0.707  1.00 37.68  ? 230 LEU B CA  1 
ATOM   5429  C C   . LEU B 1 230 ? -4.494  -47.599 -1.810  1.00 36.71  ? 230 LEU B C   1 
ATOM   5430  O O   . LEU B 1 230 ? -4.329  -47.985 -2.963  1.00 35.36  ? 230 LEU B O   1 
ATOM   5431  C CB  . LEU B 1 230 ? -4.489  -49.262 0.062   1.00 37.52  ? 230 LEU B CB  1 
ATOM   5432  C CG  . LEU B 1 230 ? -5.233  -50.303 -0.801  1.00 38.07  ? 230 LEU B CG  1 
ATOM   5433  C CD1 . LEU B 1 230 ? -4.283  -51.127 -1.671  1.00 37.14  ? 230 LEU B CD1 1 
ATOM   5434  C CD2 . LEU B 1 230 ? -6.052  -51.225 0.059   1.00 41.46  ? 230 LEU B CD2 1 
ATOM   5435  N N   . TYR B 1 231 ? -5.435  -46.731 -1.406  1.00 37.21  ? 231 TYR B N   1 
ATOM   5436  C CA  . TYR B 1 231 ? -6.342  -46.003 -2.291  1.00 36.07  ? 231 TYR B CA  1 
ATOM   5437  C C   . TYR B 1 231 ? -5.549  -45.263 -3.383  1.00 32.12  ? 231 TYR B C   1 
ATOM   5438  O O   . TYR B 1 231 ? -5.835  -45.386 -4.576  1.00 34.00  ? 231 TYR B O   1 
ATOM   5439  C CB  . TYR B 1 231 ? -7.251  -45.088 -1.468  1.00 39.12  ? 231 TYR B CB  1 
ATOM   5440  C CG  . TYR B 1 231 ? -8.221  -44.293 -2.296  1.00 45.72  ? 231 TYR B CG  1 
ATOM   5441  C CD1 . TYR B 1 231 ? -7.754  -43.280 -3.126  1.00 44.48  ? 231 TYR B CD1 1 
ATOM   5442  C CD2 . TYR B 1 231 ? -9.575  -44.571 -2.309  1.00 44.88  ? 231 TYR B CD2 1 
ATOM   5443  C CE1 . TYR B 1 231 ? -8.601  -42.585 -3.959  1.00 42.95  ? 231 TYR B CE1 1 
ATOM   5444  C CE2 . TYR B 1 231 ? -10.444 -43.860 -3.127  1.00 47.88  ? 231 TYR B CE2 1 
ATOM   5445  C CZ  . TYR B 1 231 ? -9.951  -42.861 -3.947  1.00 44.00  ? 231 TYR B CZ  1 
ATOM   5446  O OH  . TYR B 1 231 ? -10.728 -42.102 -4.794  1.00 52.73  ? 231 TYR B OH  1 
ATOM   5447  N N   . MET B 1 232 ? -4.515  -44.537 -2.998  1.00 32.64  ? 232 MET B N   1 
ATOM   5448  C CA  . MET B 1 232 ? -3.757  -43.747 -3.946  1.00 33.98  ? 232 MET B CA  1 
ATOM   5449  C C   . MET B 1 232 ? -2.992  -44.692 -4.877  1.00 37.99  ? 232 MET B C   1 
ATOM   5450  O O   . MET B 1 232 ? -2.884  -44.463 -6.088  1.00 36.65  ? 232 MET B O   1 
ATOM   5451  C CB  . MET B 1 232 ? -2.802  -42.803 -3.218  1.00 31.22  ? 232 MET B CB  1 
ATOM   5452  C CG  . MET B 1 232 ? -3.543  -41.741 -2.393  1.00 39.15  ? 232 MET B CG  1 
ATOM   5453  S SD  . MET B 1 232 ? -4.480  -40.653 -3.466  1.00 41.87  ? 232 MET B SD  1 
ATOM   5454  C CE  . MET B 1 232 ? -5.819  -40.105 -2.412  1.00 35.69  ? 232 MET B CE  1 
ATOM   5455  N N   . PHE B 1 233 ? -2.489  -45.795 -4.320  1.00 35.92  ? 233 PHE B N   1 
ATOM   5456  C CA  . PHE B 1 233 ? -1.804  -46.790 -5.132  1.00 35.19  ? 233 PHE B CA  1 
ATOM   5457  C C   . PHE B 1 233 ? -2.753  -47.407 -6.166  1.00 34.46  ? 233 PHE B C   1 
ATOM   5458  O O   . PHE B 1 233 ? -2.391  -47.546 -7.324  1.00 34.70  ? 233 PHE B O   1 
ATOM   5459  C CB  . PHE B 1 233 ? -1.183  -47.851 -4.224  1.00 43.03  ? 233 PHE B CB  1 
ATOM   5460  C CG  . PHE B 1 233 ? -0.799  -49.144 -4.893  1.00 34.86  ? 233 PHE B CG  1 
ATOM   5461  C CD1 . PHE B 1 233 ? 0.444   -49.300 -5.486  1.00 38.44  ? 233 PHE B CD1 1 
ATOM   5462  C CD2 . PHE B 1 233 ? -1.681  -50.206 -4.898  1.00 37.94  ? 233 PHE B CD2 1 
ATOM   5463  C CE1 . PHE B 1 233 ? 0.802   -50.517 -6.050  1.00 42.14  ? 233 PHE B CE1 1 
ATOM   5464  C CE2 . PHE B 1 233 ? -1.334  -51.418 -5.494  1.00 40.68  ? 233 PHE B CE2 1 
ATOM   5465  C CZ  . PHE B 1 233 ? -0.089  -51.573 -6.057  1.00 41.52  ? 233 PHE B CZ  1 
ATOM   5466  N N   . LEU B 1 234 ? -3.954  -47.786 -5.749  1.00 29.64  ? 234 LEU B N   1 
ATOM   5467  C CA  . LEU B 1 234 ? -4.848  -48.548 -6.603  1.00 32.29  ? 234 LEU B CA  1 
ATOM   5468  C C   . LEU B 1 234 ? -5.389  -47.727 -7.764  1.00 38.70  ? 234 LEU B C   1 
ATOM   5469  O O   . LEU B 1 234 ? -5.676  -48.300 -8.821  1.00 33.28  ? 234 LEU B O   1 
ATOM   5470  C CB  . LEU B 1 234 ? -6.034  -49.054 -5.781  1.00 36.81  ? 234 LEU B CB  1 
ATOM   5471  C CG  . LEU B 1 234 ? -5.731  -50.219 -4.834  1.00 37.22  ? 234 LEU B CG  1 
ATOM   5472  C CD1 . LEU B 1 234 ? -7.022  -50.658 -4.163  1.00 39.58  ? 234 LEU B CD1 1 
ATOM   5473  C CD2 . LEU B 1 234 ? -5.065  -51.377 -5.569  1.00 40.79  ? 234 LEU B CD2 1 
ATOM   5474  N N   . HIS B 1 235 ? -5.635  -46.425 -7.523  1.00 35.14  ? 235 HIS B N   1 
ATOM   5475  C CA  . HIS B 1 235 ? -6.357  -45.605 -8.476  1.00 32.17  ? 235 HIS B CA  1 
ATOM   5476  C C   . HIS B 1 235 ? -5.392  -44.820 -9.351  1.00 29.42  ? 235 HIS B C   1 
ATOM   5477  O O   . HIS B 1 235 ? -5.824  -43.932 -10.069 1.00 35.13  ? 235 HIS B O   1 
ATOM   5478  C CB  . HIS B 1 235 ? -7.310  -44.631 -7.799  1.00 33.20  ? 235 HIS B CB  1 
ATOM   5479  C CG  . HIS B 1 235 ? -8.473  -45.303 -7.205  1.00 36.77  ? 235 HIS B CG  1 
ATOM   5480  N ND1 . HIS B 1 235 ? -8.426  -45.830 -5.934  1.00 45.15  ? 235 HIS B ND1 1 
ATOM   5481  C CD2 . HIS B 1 235 ? -9.710  -45.490 -7.657  1.00 43.09  ? 235 HIS B CD2 1 
ATOM   5482  C CE1 . HIS B 1 235 ? -9.617  -46.346 -5.641  1.00 41.46  ? 235 HIS B CE1 1 
ATOM   5483  N NE2 . HIS B 1 235 ? -10.403 -46.159 -6.679  1.00 42.87  ? 235 HIS B NE2 1 
ATOM   5484  N N   . SER B 1 236 ? -4.102  -45.099 -9.201  1.00 29.57  ? 236 SER B N   1 
ATOM   5485  C CA  . SER B 1 236 ? -3.045  -44.290 -9.762  1.00 30.61  ? 236 SER B CA  1 
ATOM   5486  C C   . SER B 1 236 ? -3.162  -44.182 -11.290 1.00 35.51  ? 236 SER B C   1 
ATOM   5487  O O   . SER B 1 236 ? -2.862  -43.123 -11.838 1.00 33.48  ? 236 SER B O   1 
ATOM   5488  C CB  . SER B 1 236 ? -1.721  -44.876 -9.370  1.00 33.57  ? 236 SER B CB  1 
ATOM   5489  O OG  . SER B 1 236 ? -1.609  -46.206 -9.876  1.00 39.76  ? 236 SER B OG  1 
ATOM   5490  N N   . ASP B 1 237 ? -3.585  -45.265 -11.979 1.00 33.81  ? 237 ASP B N   1 
ATOM   5491  C CA  . ASP B 1 237 ? -3.440  -45.364 -13.427 1.00 35.73  ? 237 ASP B CA  1 
ATOM   5492  C C   . ASP B 1 237 ? -4.311  -46.500 -13.962 1.00 37.77  ? 237 ASP B C   1 
ATOM   5493  O O   . ASP B 1 237 ? -4.402  -47.542 -13.303 1.00 32.29  ? 237 ASP B O   1 
ATOM   5494  C CB  . ASP B 1 237 ? -1.981  -45.660 -13.805 1.00 36.92  ? 237 ASP B CB  1 
ATOM   5495  C CG  . ASP B 1 237 ? -1.594  -45.228 -15.217 1.00 47.81  ? 237 ASP B CG  1 
ATOM   5496  O OD1 . ASP B 1 237 ? -1.967  -44.059 -15.601 1.00 46.74  ? 237 ASP B OD1 1 
ATOM   5497  O OD2 . ASP B 1 237 ? -0.877  -46.024 -15.926 1.00 45.48  ? 237 ASP B OD2 1 
ATOM   5498  N N   . HIS B 1 238 ? -4.892  -46.301 -15.165 1.00 36.40  ? 238 HIS B N   1 
ATOM   5499  C CA  . HIS B 1 238 ? -5.738  -47.297 -15.808 1.00 35.58  ? 238 HIS B CA  1 
ATOM   5500  C C   . HIS B 1 238 ? -5.710  -47.087 -17.318 1.00 29.94  ? 238 HIS B C   1 
ATOM   5501  O O   . HIS B 1 238 ? -6.666  -46.601 -17.892 1.00 29.00  ? 238 HIS B O   1 
ATOM   5502  C CB  . HIS B 1 238 ? -7.145  -47.241 -15.203 1.00 37.07  ? 238 HIS B CB  1 
ATOM   5503  C CG  . HIS B 1 238 ? -7.979  -48.449 -15.495 1.00 47.56  ? 238 HIS B CG  1 
ATOM   5504  N ND1 . HIS B 1 238 ? -9.040  -48.446 -16.379 1.00 49.72  ? 238 HIS B ND1 1 
ATOM   5505  C CD2 . HIS B 1 238 ? -7.912  -49.702 -15.009 1.00 47.29  ? 238 HIS B CD2 1 
ATOM   5506  C CE1 . HIS B 1 238 ? -9.589  -49.652 -16.426 1.00 48.77  ? 238 HIS B CE1 1 
ATOM   5507  N NE2 . HIS B 1 238 ? -8.915  -50.436 -15.606 1.00 47.86  ? 238 HIS B NE2 1 
ATOM   5508  N N   . GLU B 1 239 ? -4.564  -47.318 -17.942 1.00 31.15  ? 239 GLU B N   1 
ATOM   5509  C CA  . GLU B 1 239 ? -4.417  -47.067 -19.371 1.00 37.74  ? 239 GLU B CA  1 
ATOM   5510  C C   . GLU B 1 239 ? -4.622  -45.577 -19.730 1.00 35.96  ? 239 GLU B C   1 
ATOM   5511  O O   . GLU B 1 239 ? -4.726  -44.704 -18.874 1.00 35.15  ? 239 GLU B O   1 
ATOM   5512  C CB  . GLU B 1 239 ? -5.341  -48.034 -20.143 1.00 37.68  ? 239 GLU B CB  1 
ATOM   5513  C CG  . GLU B 1 239 ? -4.827  -49.469 -20.170 1.00 42.82  ? 239 GLU B CG  1 
ATOM   5514  C CD  . GLU B 1 239 ? -5.377  -50.339 -21.305 1.00 46.59  ? 239 GLU B CD  1 
ATOM   5515  O OE1 . GLU B 1 239 ? -4.779  -51.443 -21.596 1.00 46.35  ? 239 GLU B OE1 1 
ATOM   5516  O OE2 . GLU B 1 239 ? -6.434  -49.945 -21.872 1.00 45.06  ? 239 GLU B OE2 1 
ATOM   5517  N N   . GLY B 1 240 ? -4.591  -45.274 -21.037 1.00 32.66  ? 240 GLY B N   1 
ATOM   5518  C CA  . GLY B 1 240 ? -4.507  -43.918 -21.542 1.00 29.32  ? 240 GLY B CA  1 
ATOM   5519  C C   . GLY B 1 240 ? -5.836  -43.413 -22.096 1.00 29.84  ? 240 GLY B C   1 
ATOM   5520  O O   . GLY B 1 240 ? -5.949  -42.245 -22.473 1.00 32.60  ? 240 GLY B O   1 
ATOM   5521  N N   . GLY B 1 241 ? -6.829  -44.294 -22.148 1.00 29.98  ? 241 GLY B N   1 
ATOM   5522  C CA  . GLY B 1 241 ? -8.004  -44.112 -22.975 1.00 30.19  ? 241 GLY B CA  1 
ATOM   5523  C C   . GLY B 1 241 ? -9.191  -43.502 -22.243 1.00 31.23  ? 241 GLY B C   1 
ATOM   5524  O O   . GLY B 1 241 ? -10.050 -42.932 -22.888 1.00 33.93  ? 241 GLY B O   1 
ATOM   5525  N N   . ASN B 1 242 ? -9.212  -43.549 -20.912 1.00 29.45  ? 242 ASN B N   1 
ATOM   5526  C CA  . ASN B 1 242 ? -10.311 -42.967 -20.146 1.00 32.88  ? 242 ASN B CA  1 
ATOM   5527  C C   . ASN B 1 242 ? -10.293 -41.428 -20.291 1.00 27.48  ? 242 ASN B C   1 
ATOM   5528  O O   . ASN B 1 242 ? -9.305  -40.818 -20.707 1.00 27.12  ? 242 ASN B O   1 
ATOM   5529  C CB  . ASN B 1 242 ? -10.291 -43.482 -18.700 1.00 31.61  ? 242 ASN B CB  1 
ATOM   5530  C CG  . ASN B 1 242 ? -9.063  -42.988 -17.938 1.00 35.81  ? 242 ASN B CG  1 
ATOM   5531  O OD1 . ASN B 1 242 ? -8.870  -41.791 -17.696 1.00 32.80  ? 242 ASN B OD1 1 
ATOM   5532  N ND2 . ASN B 1 242 ? -8.167  -43.902 -17.627 1.00 31.98  ? 242 ASN B ND2 1 
ATOM   5533  N N   . VAL B 1 243 ? -11.431 -40.773 -20.043 1.00 28.49  ? 243 VAL B N   1 
ATOM   5534  C CA  . VAL B 1 243 ? -11.567 -39.373 -20.444 1.00 33.13  ? 243 VAL B CA  1 
ATOM   5535  C C   . VAL B 1 243 ? -10.460 -38.488 -19.837 1.00 29.83  ? 243 VAL B C   1 
ATOM   5536  O O   . VAL B 1 243 ? -9.885  -37.650 -20.536 1.00 30.90  ? 243 VAL B O   1 
ATOM   5537  C CB  . VAL B 1 243 ? -12.968 -38.834 -20.116 1.00 34.14  ? 243 VAL B CB  1 
ATOM   5538  C CG1 . VAL B 1 243 ? -12.979 -37.308 -20.085 1.00 34.42  ? 243 VAL B CG1 1 
ATOM   5539  C CG2 . VAL B 1 243 ? -14.001 -39.361 -21.113 1.00 32.45  ? 243 VAL B CG2 1 
ATOM   5540  N N   . SER B 1 244 ? -10.116 -38.708 -18.556 1.00 31.03  ? 244 SER B N   1 
ATOM   5541  C CA  . SER B 1 244 ? -9.182  -37.817 -17.884 1.00 33.78  ? 244 SER B CA  1 
ATOM   5542  C C   . SER B 1 244 ? -7.737  -38.067 -18.329 1.00 32.13  ? 244 SER B C   1 
ATOM   5543  O O   . SER B 1 244 ? -7.008  -37.118 -18.595 1.00 29.61  ? 244 SER B O   1 
ATOM   5544  C CB  . SER B 1 244 ? -9.368  -37.828 -16.357 1.00 32.93  ? 244 SER B CB  1 
ATOM   5545  O OG  . SER B 1 244 ? -9.238  -39.114 -15.787 1.00 34.57  ? 244 SER B OG  1 
ATOM   5546  N N   . ALA B 1 245 ? -7.304  -39.336 -18.409 1.00 29.98  ? 245 ALA B N   1 
ATOM   5547  C CA  . ALA B 1 245 ? -5.988  -39.680 -18.936 1.00 28.25  ? 245 ALA B CA  1 
ATOM   5548  C C   . ALA B 1 245 ? -5.830  -39.200 -20.385 1.00 27.97  ? 245 ALA B C   1 
ATOM   5549  O O   . ALA B 1 245 ? -4.807  -38.647 -20.779 1.00 29.78  ? 245 ALA B O   1 
ATOM   5550  C CB  . ALA B 1 245 ? -5.790  -41.182 -18.867 1.00 31.87  ? 245 ALA B CB  1 
ATOM   5551  N N   . HIS B 1 246 ? -6.870  -39.357 -21.178 1.00 28.53  ? 246 HIS B N   1 
ATOM   5552  C CA  . HIS B 1 246 ? -6.819  -38.930 -22.565 1.00 29.09  ? 246 HIS B CA  1 
ATOM   5553  C C   . HIS B 1 246 ? -6.755  -37.407 -22.668 1.00 26.10  ? 246 HIS B C   1 
ATOM   5554  O O   . HIS B 1 246 ? -5.975  -36.888 -23.452 1.00 28.13  ? 246 HIS B O   1 
ATOM   5555  C CB  . HIS B 1 246 ? -7.997  -39.540 -23.326 1.00 29.05  ? 246 HIS B CB  1 
ATOM   5556  C CG  . HIS B 1 246 ? -8.049  -39.250 -24.795 1.00 27.21  ? 246 HIS B CG  1 
ATOM   5557  N ND1 . HIS B 1 246 ? -9.206  -39.442 -25.537 1.00 30.57  ? 246 HIS B ND1 1 
ATOM   5558  C CD2 . HIS B 1 246 ? -7.106  -38.821 -25.641 1.00 28.84  ? 246 HIS B CD2 1 
ATOM   5559  C CE1 . HIS B 1 246 ? -8.963  -39.078 -26.794 1.00 31.41  ? 246 HIS B CE1 1 
ATOM   5560  N NE2 . HIS B 1 246 ? -7.673  -38.739 -26.888 1.00 30.41  ? 246 HIS B NE2 1 
ATOM   5561  N N   . THR B 1 247 ? -7.563  -36.694 -21.874 1.00 25.88  ? 247 THR B N   1 
ATOM   5562  C CA  . THR B 1 247 ? -7.527  -35.237 -21.863 1.00 25.14  ? 247 THR B CA  1 
ATOM   5563  C C   . THR B 1 247 ? -6.096  -34.741 -21.550 1.00 25.70  ? 247 THR B C   1 
ATOM   5564  O O   . THR B 1 247 ? -5.547  -33.838 -22.208 1.00 27.57  ? 247 THR B O   1 
ATOM   5565  C CB  . THR B 1 247 ? -8.554  -34.664 -20.871 1.00 27.06  ? 247 THR B CB  1 
ATOM   5566  O OG1 . THR B 1 247 ? -9.848  -35.125 -21.284 1.00 28.44  ? 247 THR B OG1 1 
ATOM   5567  C CG2 . THR B 1 247 ? -8.491  -33.152 -20.802 1.00 26.12  ? 247 THR B CG2 1 
ATOM   5568  N N   . ASN B 1 248 ? -5.497  -35.358 -20.553 1.00 28.74  ? 248 ASN B N   1 
ATOM   5569  C CA  . ASN B 1 248 ? -4.137  -35.073 -20.145 1.00 27.04  ? 248 ASN B CA  1 
ATOM   5570  C C   . ASN B 1 248 ? -3.181  -35.187 -21.328 1.00 29.42  ? 248 ASN B C   1 
ATOM   5571  O O   . ASN B 1 248 ? -2.364  -34.285 -21.574 1.00 26.07  ? 248 ASN B O   1 
ATOM   5572  C CB  . ASN B 1 248 ? -3.736  -35.997 -18.999 1.00 27.35  ? 248 ASN B CB  1 
ATOM   5573  C CG  . ASN B 1 248 ? -2.336  -35.729 -18.491 1.00 31.49  ? 248 ASN B CG  1 
ATOM   5574  O OD1 . ASN B 1 248 ? -1.464  -36.608 -18.516 1.00 33.89  ? 248 ASN B OD1 1 
ATOM   5575  N ND2 . ASN B 1 248 ? -2.121  -34.506 -18.033 1.00 26.29  ? 248 ASN B ND2 1 
ATOM   5576  N N   . LEU B 1 249 ? -3.246  -36.325 -22.031 1.00 26.51  ? 249 LEU B N   1 
ATOM   5577  C CA  . LEU B 1 249 ? -2.341  -36.601 -23.131 1.00 27.76  ? 249 LEU B CA  1 
ATOM   5578  C C   . LEU B 1 249 ? -2.594  -35.628 -24.273 1.00 26.45  ? 249 LEU B C   1 
ATOM   5579  O O   . LEU B 1 249 ? -1.666  -35.117 -24.850 1.00 27.58  ? 249 LEU B O   1 
ATOM   5580  C CB  . LEU B 1 249 ? -2.521  -38.051 -23.610 1.00 31.10  ? 249 LEU B CB  1 
ATOM   5581  C CG  . LEU B 1 249 ? -2.051  -39.138 -22.645 1.00 36.23  ? 249 LEU B CG  1 
ATOM   5582  C CD1 . LEU B 1 249 ? -2.483  -40.535 -23.129 1.00 42.92  ? 249 LEU B CD1 1 
ATOM   5583  C CD2 . LEU B 1 249 ? -0.551  -39.087 -22.465 1.00 38.35  ? 249 LEU B CD2 1 
ATOM   5584  N N   . LEU B 1 250 ? -3.865  -35.365 -24.564 1.00 29.71  ? 250 LEU B N   1 
ATOM   5585  C CA  . LEU B 1 250 ? -4.239  -34.483 -25.639 1.00 27.96  ? 250 LEU B CA  1 
ATOM   5586  C C   . LEU B 1 250 ? -3.671  -33.073 -25.442 1.00 28.69  ? 250 LEU B C   1 
ATOM   5587  O O   . LEU B 1 250 ? -3.027  -32.519 -26.330 1.00 27.17  ? 250 LEU B O   1 
ATOM   5588  C CB  . LEU B 1 250 ? -5.764  -34.501 -25.688 1.00 28.77  ? 250 LEU B CB  1 
ATOM   5589  C CG  . LEU B 1 250 ? -6.430  -33.568 -26.692 1.00 32.79  ? 250 LEU B CG  1 
ATOM   5590  C CD1 . LEU B 1 250 ? -5.869  -33.775 -28.091 1.00 35.50  ? 250 LEU B CD1 1 
ATOM   5591  C CD2 . LEU B 1 250 ? -7.942  -33.818 -26.690 1.00 37.48  ? 250 LEU B CD2 1 
ATOM   5592  N N   . VAL B 1 251 ? -3.890  -32.483 -24.270 1.00 28.70  ? 251 VAL B N   1 
ATOM   5593  C CA  . VAL B 1 251 ? -3.423  -31.128 -23.999 1.00 26.53  ? 251 VAL B CA  1 
ATOM   5594  C C   . VAL B 1 251 ? -1.898  -31.149 -23.917 1.00 25.38  ? 251 VAL B C   1 
ATOM   5595  O O   . VAL B 1 251 ? -1.216  -30.237 -24.380 1.00 26.72  ? 251 VAL B O   1 
ATOM   5596  C CB  . VAL B 1 251 ? -4.086  -30.611 -22.698 1.00 25.42  ? 251 VAL B CB  1 
ATOM   5597  C CG1 . VAL B 1 251 ? -3.497  -29.300 -22.249 1.00 27.50  ? 251 VAL B CG1 1 
ATOM   5598  C CG2 . VAL B 1 251 ? -5.610  -30.500 -22.842 1.00 27.81  ? 251 VAL B CG2 1 
ATOM   5599  N N   . ASN B 1 252 ? -1.336  -32.174 -23.295 1.00 28.16  ? 252 ASN B N   1 
ATOM   5600  C CA  . ASN B 1 252 ? 0.120   -32.364 -23.272 1.00 28.61  ? 252 ASN B CA  1 
ATOM   5601  C C   . ASN B 1 252 ? 0.745   -32.335 -24.677 1.00 30.32  ? 252 ASN B C   1 
ATOM   5602  O O   . ASN B 1 252 ? 1.848   -31.778 -24.858 1.00 27.75  ? 252 ASN B O   1 
ATOM   5603  C CB  . ASN B 1 252 ? 0.487   -33.676 -22.556 1.00 32.67  ? 252 ASN B CB  1 
ATOM   5604  C CG  . ASN B 1 252 ? 1.969   -33.963 -22.591 1.00 32.80  ? 252 ASN B CG  1 
ATOM   5605  O OD1 . ASN B 1 252 ? 2.464   -34.658 -23.488 1.00 31.86  ? 252 ASN B OD1 1 
ATOM   5606  N ND2 . ASN B 1 252 ? 2.688   -33.362 -21.662 1.00 33.47  ? 252 ASN B ND2 1 
ATOM   5607  N N   . SER B 1 253 ? 0.033   -32.896 -25.679 1.00 30.73  ? 253 SER B N   1 
ATOM   5608  C CA  . SER B 1 253 ? 0.553   -33.084 -27.039 1.00 27.08  ? 253 SER B CA  1 
ATOM   5609  C C   . SER B 1 253 ? 0.779   -31.744 -27.730 1.00 28.19  ? 253 SER B C   1 
ATOM   5610  O O   . SER B 1 253 ? 1.524   -31.672 -28.709 1.00 29.74  ? 253 SER B O   1 
ATOM   5611  C CB  . SER B 1 253 ? -0.382  -33.978 -27.882 1.00 24.87  ? 253 SER B CB  1 
ATOM   5612  O OG  . SER B 1 253 ? -1.563  -33.277 -28.362 1.00 25.03  ? 253 SER B OG  1 
ATOM   5613  N N   . ALA B 1 254 ? 0.093   -30.689 -27.260 1.00 26.55  ? 254 ALA B N   1 
ATOM   5614  C CA  . ALA B 1 254 ? 0.307   -29.340 -27.782 1.00 26.30  ? 254 ALA B CA  1 
ATOM   5615  C C   . ALA B 1 254 ? 1.460   -28.601 -27.080 1.00 28.12  ? 254 ALA B C   1 
ATOM   5616  O O   . ALA B 1 254 ? 1.674   -27.423 -27.350 1.00 28.07  ? 254 ALA B O   1 
ATOM   5617  C CB  . ALA B 1 254 ? -0.957  -28.531 -27.698 1.00 29.31  ? 254 ALA B CB  1 
ATOM   5618  N N   . TYR B 1 255 ? 2.218   -29.301 -26.221 1.00 30.05  ? 255 TYR B N   1 
ATOM   5619  C CA  . TYR B 1 255 ? 3.299   -28.763 -25.393 1.00 29.69  ? 255 TYR B CA  1 
ATOM   5620  C C   . TYR B 1 255 ? 2.766   -27.907 -24.233 1.00 31.85  ? 255 TYR B C   1 
ATOM   5621  O O   . TYR B 1 255 ? 3.501   -27.110 -23.666 1.00 27.18  ? 255 TYR B O   1 
ATOM   5622  C CB  . TYR B 1 255 ? 4.345   -28.015 -26.230 1.00 35.69  ? 255 TYR B CB  1 
ATOM   5623  C CG  . TYR B 1 255 ? 5.267   -28.842 -27.106 1.00 34.20  ? 255 TYR B CG  1 
ATOM   5624  C CD1 . TYR B 1 255 ? 5.249   -30.231 -27.126 1.00 32.54  ? 255 TYR B CD1 1 
ATOM   5625  C CD2 . TYR B 1 255 ? 6.172   -28.203 -27.946 1.00 37.67  ? 255 TYR B CD2 1 
ATOM   5626  C CE1 . TYR B 1 255 ? 6.104   -30.956 -27.956 1.00 33.82  ? 255 TYR B CE1 1 
ATOM   5627  C CE2 . TYR B 1 255 ? 7.060   -28.907 -28.751 1.00 36.96  ? 255 TYR B CE2 1 
ATOM   5628  C CZ  . TYR B 1 255 ? 7.005   -30.292 -28.772 1.00 39.72  ? 255 TYR B CZ  1 
ATOM   5629  O OH  . TYR B 1 255 ? 7.869   -30.979 -29.597 1.00 44.39  ? 255 TYR B OH  1 
ATOM   5630  N N   . SER B 1 256 ? 1.503   -28.091 -23.828 1.00 32.91  ? 256 SER B N   1 
ATOM   5631  C CA  . SER B 1 256 ? 1.018   -27.440 -22.619 1.00 28.25  ? 256 SER B CA  1 
ATOM   5632  C C   . SER B 1 256 ? 1.593   -28.172 -21.411 1.00 29.93  ? 256 SER B C   1 
ATOM   5633  O O   . SER B 1 256 ? 1.605   -29.401 -21.367 1.00 34.93  ? 256 SER B O   1 
ATOM   5634  C CB  . SER B 1 256 ? -0.475  -27.404 -22.571 1.00 28.84  ? 256 SER B CB  1 
ATOM   5635  O OG  . SER B 1 256 ? -0.996  -26.447 -23.469 1.00 31.39  ? 256 SER B OG  1 
ATOM   5636  N N   . ASP B 1 257 ? 2.010   -27.412 -20.394 1.00 29.42  ? 257 ASP B N   1 
ATOM   5637  C CA  . ASP B 1 257 ? 2.633   -27.986 -19.214 1.00 24.26  ? 257 ASP B CA  1 
ATOM   5638  C C   . ASP B 1 257 ? 1.602   -28.771 -18.404 1.00 23.35  ? 257 ASP B C   1 
ATOM   5639  O O   . ASP B 1 257 ? 0.405   -28.711 -18.660 1.00 28.71  ? 257 ASP B O   1 
ATOM   5640  C CB  . ASP B 1 257 ? 3.332   -26.888 -18.408 1.00 28.78  ? 257 ASP B CB  1 
ATOM   5641  C CG  . ASP B 1 257 ? 2.360   -25.843 -17.870 1.00 31.65  ? 257 ASP B CG  1 
ATOM   5642  O OD1 . ASP B 1 257 ? 1.572   -26.202 -17.004 1.00 32.42  ? 257 ASP B OD1 1 
ATOM   5643  O OD2 . ASP B 1 257 ? 2.362   -24.720 -18.376 1.00 35.34  ? 257 ASP B OD2 1 
ATOM   5644  N N   . ILE B 1 258 ? 2.093   -29.466 -17.372 1.00 25.82  ? 258 ILE B N   1 
ATOM   5645  C CA  . ILE B 1 258 ? 1.328   -30.394 -16.573 1.00 26.88  ? 258 ILE B CA  1 
ATOM   5646  C C   . ILE B 1 258 ? 0.239   -29.702 -15.756 1.00 27.52  ? 258 ILE B C   1 
ATOM   5647  O O   . ILE B 1 258 ? -0.748  -30.360 -15.434 1.00 25.05  ? 258 ILE B O   1 
ATOM   5648  C CB  . ILE B 1 258 ? 2.278   -31.216 -15.687 1.00 28.43  ? 258 ILE B CB  1 
ATOM   5649  C CG1 . ILE B 1 258 ? 1.609   -32.455 -15.081 1.00 27.11  ? 258 ILE B CG1 1 
ATOM   5650  C CG2 . ILE B 1 258 ? 2.849   -30.341 -14.583 1.00 30.96  ? 258 ILE B CG2 1 
ATOM   5651  C CD1 . ILE B 1 258 ? 1.175   -33.494 -16.054 1.00 29.72  ? 258 ILE B CD1 1 
ATOM   5652  N N   . TYR B 1 259 ? 0.419   -28.426 -15.372 1.00 23.53  ? 259 TYR B N   1 
ATOM   5653  C CA  . TYR B 1 259 ? -0.632  -27.717 -14.666 1.00 25.97  ? 259 TYR B CA  1 
ATOM   5654  C C   . TYR B 1 259 ? -1.853  -27.535 -15.587 1.00 24.40  ? 259 TYR B C   1 
ATOM   5655  O O   . TYR B 1 259 ? -2.997  -27.735 -15.178 1.00 24.67  ? 259 TYR B O   1 
ATOM   5656  C CB  . TYR B 1 259 ? -0.090  -26.380 -14.148 1.00 25.22  ? 259 TYR B CB  1 
ATOM   5657  C CG  . TYR B 1 259 ? 1.007   -26.520 -13.116 1.00 26.51  ? 259 TYR B CG  1 
ATOM   5658  C CD1 . TYR B 1 259 ? 0.735   -26.854 -11.804 1.00 25.93  ? 259 TYR B CD1 1 
ATOM   5659  C CD2 . TYR B 1 259 ? 2.334   -26.382 -13.478 1.00 29.24  ? 259 TYR B CD2 1 
ATOM   5660  C CE1 . TYR B 1 259 ? 1.748   -26.996 -10.865 1.00 29.28  ? 259 TYR B CE1 1 
ATOM   5661  C CE2 . TYR B 1 259 ? 3.361   -26.534 -12.565 1.00 28.14  ? 259 TYR B CE2 1 
ATOM   5662  C CZ  . TYR B 1 259 ? 3.069   -26.884 -11.264 1.00 29.10  ? 259 TYR B CZ  1 
ATOM   5663  O OH  . TYR B 1 259 ? 4.117   -26.971 -10.390 1.00 28.02  ? 259 TYR B OH  1 
ATOM   5664  N N   . ARG B 1 260 ? -1.583  -27.230 -16.854 1.00 20.50  ? 260 ARG B N   1 
ATOM   5665  C CA  . ARG B 1 260 ? -2.614  -27.043 -17.840 1.00 23.32  ? 260 ARG B CA  1 
ATOM   5666  C C   . ARG B 1 260 ? -3.267  -28.368 -18.248 1.00 24.39  ? 260 ARG B C   1 
ATOM   5667  O O   . ARG B 1 260 ? -4.480  -28.422 -18.373 1.00 23.90  ? 260 ARG B O   1 
ATOM   5668  C CB  . ARG B 1 260 ? -2.022  -26.311 -19.031 1.00 24.94  ? 260 ARG B CB  1 
ATOM   5669  C CG  . ARG B 1 260 ? -2.040  -24.810 -18.849 1.00 25.47  ? 260 ARG B CG  1 
ATOM   5670  C CD  . ARG B 1 260 ? -1.327  -24.129 -19.982 1.00 26.28  ? 260 ARG B CD  1 
ATOM   5671  N NE  . ARG B 1 260 ? -1.436  -22.700 -19.880 1.00 28.89  ? 260 ARG B NE  1 
ATOM   5672  C CZ  . ARG B 1 260 ? -0.552  -21.838 -20.373 1.00 30.29  ? 260 ARG B CZ  1 
ATOM   5673  N NH1 . ARG B 1 260 ? -0.750  -20.529 -20.256 1.00 27.63  ? 260 ARG B NH1 1 
ATOM   5674  N NH2 . ARG B 1 260 ? 0.536   -22.284 -20.971 1.00 31.50  ? 260 ARG B NH2 1 
ATOM   5675  N N   . SER B 1 261 ? -2.451  -29.408 -18.479 1.00 24.51  ? 261 SER B N   1 
ATOM   5676  C CA  . SER B 1 261 ? -2.937  -30.694 -18.943 1.00 24.90  ? 261 SER B CA  1 
ATOM   5677  C C   . SER B 1 261 ? -3.708  -31.411 -17.840 1.00 24.43  ? 261 SER B C   1 
ATOM   5678  O O   . SER B 1 261 ? -4.734  -32.021 -18.103 1.00 25.71  ? 261 SER B O   1 
ATOM   5679  C CB  . SER B 1 261 ? -1.806  -31.566 -19.543 1.00 24.39  ? 261 SER B CB  1 
ATOM   5680  O OG  . SER B 1 261 ? -0.909  -32.132 -18.574 1.00 24.96  ? 261 SER B OG  1 
ATOM   5681  N N   . PHE B 1 262 ? -3.217  -31.326 -16.601 1.00 27.07  ? 262 PHE B N   1 
ATOM   5682  C CA  . PHE B 1 262 ? -3.815  -32.053 -15.501 1.00 23.29  ? 262 PHE B CA  1 
ATOM   5683  C C   . PHE B 1 262 ? -5.064  -31.327 -14.999 1.00 25.40  ? 262 PHE B C   1 
ATOM   5684  O O   . PHE B 1 262 ? -6.036  -31.976 -14.700 1.00 23.47  ? 262 PHE B O   1 
ATOM   5685  C CB  . PHE B 1 262 ? -2.809  -32.319 -14.386 1.00 24.03  ? 262 PHE B CB  1 
ATOM   5686  C CG  . PHE B 1 262 ? -3.399  -33.248 -13.364 1.00 25.78  ? 262 PHE B CG  1 
ATOM   5687  C CD1 . PHE B 1 262 ? -3.694  -34.567 -13.715 1.00 28.43  ? 262 PHE B CD1 1 
ATOM   5688  C CD2 . PHE B 1 262 ? -3.793  -32.789 -12.121 1.00 26.44  ? 262 PHE B CD2 1 
ATOM   5689  C CE1 . PHE B 1 262 ? -4.319  -35.411 -12.799 1.00 25.11  ? 262 PHE B CE1 1 
ATOM   5690  C CE2 . PHE B 1 262 ? -4.429  -33.628 -11.211 1.00 25.64  ? 262 PHE B CE2 1 
ATOM   5691  C CZ  . PHE B 1 262 ? -4.681  -34.948 -11.555 1.00 25.88  ? 262 PHE B CZ  1 
ATOM   5692  N N   . SER B 1 263 ? -5.093  -29.992 -14.983 1.00 25.88  ? 263 SER B N   1 
ATOM   5693  C CA  . SER B 1 263 ? -6.326  -29.287 -14.642 1.00 24.77  ? 263 SER B CA  1 
ATOM   5694  C C   . SER B 1 263 ? -7.415  -29.571 -15.687 1.00 27.23  ? 263 SER B C   1 
ATOM   5695  O O   . SER B 1 263 ? -8.578  -29.795 -15.328 1.00 23.37  ? 263 SER B O   1 
ATOM   5696  C CB  . SER B 1 263 ? -6.081  -27.809 -14.425 1.00 24.34  ? 263 SER B CB  1 
ATOM   5697  O OG  . SER B 1 263 ? -5.651  -27.136 -15.610 1.00 24.71  ? 263 SER B OG  1 
ATOM   5698  N N   . ALA B 1 264 ? -7.034  -29.576 -16.980 1.00 27.06  ? 264 ALA B N   1 
ATOM   5699  C CA  . ALA B 1 264 ? -7.940  -29.989 -18.045 1.00 25.88  ? 264 ALA B CA  1 
ATOM   5700  C C   . ALA B 1 264 ? -8.515  -31.370 -17.759 1.00 26.12  ? 264 ALA B C   1 
ATOM   5701  O O   . ALA B 1 264 ? -9.729  -31.584 -17.862 1.00 28.20  ? 264 ALA B O   1 
ATOM   5702  C CB  . ALA B 1 264 ? -7.234  -29.996 -19.397 1.00 24.27  ? 264 ALA B CB  1 
ATOM   5703  N N   . ALA B 1 265 ? -7.627  -32.315 -17.408 1.00 28.76  ? 265 ALA B N   1 
ATOM   5704  C CA  . ALA B 1 265 ? -8.025  -33.676 -17.100 1.00 26.64  ? 265 ALA B CA  1 
ATOM   5705  C C   . ALA B 1 265 ? -9.036  -33.683 -15.957 1.00 26.04  ? 265 ALA B C   1 
ATOM   5706  O O   . ALA B 1 265 ? -9.963  -34.502 -15.957 1.00 24.91  ? 265 ALA B O   1 
ATOM   5707  C CB  . ALA B 1 265 ? -6.818  -34.560 -16.790 1.00 25.55  ? 265 ALA B CB  1 
ATOM   5708  N N   . MET B 1 266 ? -8.841  -32.843 -14.937 1.00 24.69  ? 266 MET B N   1 
ATOM   5709  C CA  . MET B 1 266 ? -9.766  -32.833 -13.812 1.00 26.47  ? 266 MET B CA  1 
ATOM   5710  C C   . MET B 1 266 ? -11.135 -32.293 -14.233 1.00 25.19  ? 266 MET B C   1 
ATOM   5711  O O   . MET B 1 266 ? -12.145 -32.713 -13.684 1.00 24.25  ? 266 MET B O   1 
ATOM   5712  C CB  . MET B 1 266 ? -9.212  -32.025 -12.626 1.00 30.16  ? 266 MET B CB  1 
ATOM   5713  C CG  . MET B 1 266 ? -7.960  -32.686 -12.017 1.00 25.66  ? 266 MET B CG  1 
ATOM   5714  S SD  . MET B 1 266 ? -8.331  -34.376 -11.388 1.00 28.18  ? 266 MET B SD  1 
ATOM   5715  C CE  . MET B 1 266 ? -7.855  -35.378 -12.791 1.00 24.64  ? 266 MET B CE  1 
ATOM   5716  N N   . ASN B 1 267 ? -11.201 -31.424 -15.240 1.00 25.08  ? 267 ASN B N   1 
ATOM   5717  C CA  . ASN B 1 267 ? -12.484 -30.984 -15.760 1.00 25.18  ? 267 ASN B CA  1 
ATOM   5718  C C   . ASN B 1 267 ? -13.275 -32.144 -16.409 1.00 28.35  ? 267 ASN B C   1 
ATOM   5719  O O   . ASN B 1 267 ? -14.512 -32.186 -16.356 1.00 30.17  ? 267 ASN B O   1 
ATOM   5720  C CB  . ASN B 1 267 ? -12.261 -29.821 -16.721 1.00 24.76  ? 267 ASN B CB  1 
ATOM   5721  C CG  . ASN B 1 267 ? -11.955 -28.495 -16.045 1.00 28.63  ? 267 ASN B CG  1 
ATOM   5722  O OD1 . ASN B 1 267 ? -11.993 -28.348 -14.819 1.00 25.94  ? 267 ASN B OD1 1 
ATOM   5723  N ND2 . ASN B 1 267 ? -11.735 -27.479 -16.860 1.00 26.72  ? 267 ASN B ND2 1 
ATOM   5724  N N   . GLY B 1 268 ? -12.550 -33.097 -16.987 1.00 26.97  ? 268 GLY B N   1 
ATOM   5725  C CA  . GLY B 1 268 ? -13.106 -34.319 -17.538 1.00 28.54  ? 268 GLY B CA  1 
ATOM   5726  C C   . GLY B 1 268 ? -13.521 -35.298 -16.452 1.00 29.98  ? 268 GLY B C   1 
ATOM   5727  O O   . GLY B 1 268 ? -14.628 -35.814 -16.497 1.00 28.10  ? 268 GLY B O   1 
ATOM   5728  N N   . LEU B 1 269 ? -12.663 -35.491 -15.438 1.00 27.21  ? 269 LEU B N   1 
ATOM   5729  C CA  . LEU B 1 269 ? -12.976 -36.371 -14.333 1.00 26.83  ? 269 LEU B CA  1 
ATOM   5730  C C   . LEU B 1 269 ? -14.210 -35.896 -13.576 1.00 31.01  ? 269 LEU B C   1 
ATOM   5731  O O   . LEU B 1 269 ? -14.900 -36.724 -13.006 1.00 27.59  ? 269 LEU B O   1 
ATOM   5732  C CB  . LEU B 1 269 ? -11.764 -36.465 -13.395 1.00 28.85  ? 269 LEU B CB  1 
ATOM   5733  C CG  . LEU B 1 269 ? -11.869 -37.527 -12.305 1.00 29.98  ? 269 LEU B CG  1 
ATOM   5734  C CD1 . LEU B 1 269 ? -12.031 -38.907 -12.931 1.00 32.27  ? 269 LEU B CD1 1 
ATOM   5735  C CD2 . LEU B 1 269 ? -10.656 -37.522 -11.400 1.00 30.24  ? 269 LEU B CD2 1 
ATOM   5736  N N   . ALA B 1 270 ? -14.446 -34.575 -13.538 1.00 28.99  ? 270 ALA B N   1 
ATOM   5737  C CA  . ALA B 1 270 ? -15.587 -33.981 -12.855 1.00 29.45  ? 270 ALA B CA  1 
ATOM   5738  C C   . ALA B 1 270 ? -16.916 -34.319 -13.533 1.00 32.62  ? 270 ALA B C   1 
ATOM   5739  O O   . ALA B 1 270 ? -17.972 -34.020 -12.994 1.00 31.39  ? 270 ALA B O   1 
ATOM   5740  C CB  . ALA B 1 270 ? -15.431 -32.484 -12.861 1.00 29.92  ? 270 ALA B CB  1 
ATOM   5741  N N   . GLY B 1 271 ? -16.858 -34.764 -14.784 1.00 31.18  ? 271 GLY B N   1 
ATOM   5742  C CA  . GLY B 1 271 ? -18.048 -35.169 -15.511 1.00 34.05  ? 271 GLY B CA  1 
ATOM   5743  C C   . GLY B 1 271 ? -18.819 -36.283 -14.811 1.00 29.58  ? 271 GLY B C   1 
ATOM   5744  O O   . GLY B 1 271 ? -18.244 -37.258 -14.359 1.00 30.69  ? 271 GLY B O   1 
ATOM   5745  N N   . PRO B 1 272 ? -20.158 -36.194 -14.704 1.00 29.12  ? 272 PRO B N   1 
ATOM   5746  C CA  . PRO B 1 272 ? -20.938 -37.260 -14.087 1.00 30.32  ? 272 PRO B CA  1 
ATOM   5747  C C   . PRO B 1 272 ? -20.826 -38.657 -14.683 1.00 31.38  ? 272 PRO B C   1 
ATOM   5748  O O   . PRO B 1 272 ? -21.116 -39.585 -13.976 1.00 34.67  ? 272 PRO B O   1 
ATOM   5749  C CB  . PRO B 1 272 ? -22.401 -36.826 -14.243 1.00 33.43  ? 272 PRO B CB  1 
ATOM   5750  C CG  . PRO B 1 272 ? -22.321 -35.336 -14.395 1.00 34.19  ? 272 PRO B CG  1 
ATOM   5751  C CD  . PRO B 1 272 ? -20.971 -35.023 -15.021 1.00 30.67  ? 272 PRO B CD  1 
ATOM   5752  N N   . LEU B 1 273 ? -20.413 -38.810 -15.955 1.00 34.39  ? 273 LEU B N   1 
ATOM   5753  C CA  . LEU B 1 273 ? -20.205 -40.134 -16.530 1.00 36.25  ? 273 LEU B CA  1 
ATOM   5754  C C   . LEU B 1 273 ? -18.812 -40.694 -16.220 1.00 39.37  ? 273 LEU B C   1 
ATOM   5755  O O   . LEU B 1 273 ? -18.534 -41.831 -16.565 1.00 38.71  ? 273 LEU B O   1 
ATOM   5756  C CB  . LEU B 1 273 ? -20.416 -40.049 -18.052 1.00 38.01  ? 273 LEU B CB  1 
ATOM   5757  C CG  . LEU B 1 273 ? -21.847 -39.769 -18.527 1.00 36.51  ? 273 LEU B CG  1 
ATOM   5758  C CD1 . LEU B 1 273 ? -21.926 -39.678 -20.040 1.00 35.67  ? 273 LEU B CD1 1 
ATOM   5759  C CD2 . LEU B 1 273 ? -22.788 -40.860 -18.037 1.00 39.43  ? 273 LEU B CD2 1 
ATOM   5760  N N   . HIS B 1 274 ? -17.894 -39.919 -15.611 1.00 36.67  ? 274 HIS B N   1 
ATOM   5761  C CA  . HIS B 1 274 ? -16.534 -40.406 -15.458 1.00 34.11  ? 274 HIS B CA  1 
ATOM   5762  C C   . HIS B 1 274 ? -16.139 -40.515 -13.987 1.00 35.19  ? 274 HIS B C   1 
ATOM   5763  O O   . HIS B 1 274 ? -15.323 -41.353 -13.640 1.00 41.80  ? 274 HIS B O   1 
ATOM   5764  C CB  . HIS B 1 274 ? -15.574 -39.485 -16.212 1.00 35.70  ? 274 HIS B CB  1 
ATOM   5765  C CG  . HIS B 1 274 ? -14.151 -39.928 -16.207 1.00 37.83  ? 274 HIS B CG  1 
ATOM   5766  N ND1 . HIS B 1 274 ? -13.751 -41.206 -15.884 1.00 38.03  ? 274 HIS B ND1 1 
ATOM   5767  C CD2 . HIS B 1 274 ? -13.027 -39.242 -16.500 1.00 35.28  ? 274 HIS B CD2 1 
ATOM   5768  C CE1 . HIS B 1 274 ? -12.433 -41.298 -16.014 1.00 38.76  ? 274 HIS B CE1 1 
ATOM   5769  N NE2 . HIS B 1 274 ? -11.967 -40.115 -16.391 1.00 39.75  ? 274 HIS B NE2 1 
ATOM   5770  N N   . GLY B 1 275 ? -16.658 -39.623 -13.142 1.00 36.99  ? 275 GLY B N   1 
ATOM   5771  C CA  . GLY B 1 275 ? -16.034 -39.408 -11.851 1.00 36.93  ? 275 GLY B CA  1 
ATOM   5772  C C   . GLY B 1 275 ? -16.926 -39.734 -10.668 1.00 33.94  ? 275 GLY B C   1 
ATOM   5773  O O   . GLY B 1 275 ? -16.451 -39.512 -9.575  1.00 37.32  ? 275 GLY B O   1 
ATOM   5774  N N   . LEU B 1 276 ? -18.140 -40.308 -10.878 1.00 35.34  ? 276 LEU B N   1 
ATOM   5775  C CA  . LEU B 1 276 ? -19.135 -40.507 -9.813  1.00 38.00  ? 276 LEU B CA  1 
ATOM   5776  C C   . LEU B 1 276 ? -19.426 -41.971 -9.440  1.00 36.43  ? 276 LEU B C   1 
ATOM   5777  O O   . LEU B 1 276 ? -20.220 -42.205 -8.515  1.00 31.52  ? 276 LEU B O   1 
ATOM   5778  C CB  . LEU B 1 276 ? -20.464 -39.889 -10.234 1.00 40.24  ? 276 LEU B CB  1 
ATOM   5779  C CG  . LEU B 1 276 ? -20.496 -38.393 -10.543 1.00 45.72  ? 276 LEU B CG  1 
ATOM   5780  C CD1 . LEU B 1 276 ? -21.941 -37.956 -10.740 1.00 43.33  ? 276 LEU B CD1 1 
ATOM   5781  C CD2 . LEU B 1 276 ? -19.849 -37.547 -9.456  1.00 44.80  ? 276 LEU B CD2 1 
ATOM   5782  N N   . ALA B 1 277 ? -18.847 -42.946 -10.164 1.00 33.88  ? 277 ALA B N   1 
ATOM   5783  C CA  . ALA B 1 277 ? -19.186 -44.364 -10.035 1.00 37.48  ? 277 ALA B CA  1 
ATOM   5784  C C   . ALA B 1 277 ? -19.089 -44.883 -8.593  1.00 36.50  ? 277 ALA B C   1 
ATOM   5785  O O   . ALA B 1 277 ? -20.002 -45.567 -8.108  1.00 38.73  ? 277 ALA B O   1 
ATOM   5786  C CB  . ALA B 1 277 ? -18.304 -45.186 -10.953 1.00 43.10  ? 277 ALA B CB  1 
ATOM   5787  N N   . ASN B 1 278 ? -17.980 -44.584 -7.912  1.00 36.37  ? 278 ASN B N   1 
ATOM   5788  C CA  . ASN B 1 278 ? -17.767 -44.909 -6.497  1.00 41.09  ? 278 ASN B CA  1 
ATOM   5789  C C   . ASN B 1 278 ? -18.895 -44.375 -5.594  1.00 38.81  ? 278 ASN B C   1 
ATOM   5790  O O   . ASN B 1 278 ? -19.338 -45.046 -4.647  1.00 35.19  ? 278 ASN B O   1 
ATOM   5791  C CB  . ASN B 1 278 ? -16.386 -44.354 -6.099  1.00 50.51  ? 278 ASN B CB  1 
ATOM   5792  C CG  . ASN B 1 278 ? -16.212 -44.021 -4.637  1.00 56.65  ? 278 ASN B CG  1 
ATOM   5793  O OD1 . ASN B 1 278 ? -17.092 -44.244 -3.803  1.00 65.83  ? 278 ASN B OD1 1 
ATOM   5794  N ND2 . ASN B 1 278 ? -15.039 -43.532 -4.305  1.00 47.81  ? 278 ASN B ND2 1 
ATOM   5795  N N   . GLN B 1 279 ? -19.331 -43.125 -5.832  1.00 35.32  ? 279 GLN B N   1 
ATOM   5796  C CA  . GLN B 1 279 ? -20.392 -42.526 -5.030  1.00 36.05  ? 279 GLN B CA  1 
ATOM   5797  C C   . GLN B 1 279 ? -21.739 -43.242 -5.237  1.00 43.04  ? 279 GLN B C   1 
ATOM   5798  O O   . GLN B 1 279 ? -22.511 -43.425 -4.285  1.00 38.96  ? 279 GLN B O   1 
ATOM   5799  C CB  . GLN B 1 279 ? -20.558 -41.066 -5.410  1.00 38.90  ? 279 GLN B CB  1 
ATOM   5800  C CG  . GLN B 1 279 ? -19.251 -40.307 -5.302  1.00 38.82  ? 279 GLN B CG  1 
ATOM   5801  C CD  . GLN B 1 279 ? -19.398 -38.897 -5.797  1.00 40.33  ? 279 GLN B CD  1 
ATOM   5802  O OE1 . GLN B 1 279 ? -20.438 -38.255 -5.622  1.00 37.76  ? 279 GLN B OE1 1 
ATOM   5803  N NE2 . GLN B 1 279 ? -18.337 -38.425 -6.435  1.00 40.07  ? 279 GLN B NE2 1 
ATOM   5804  N N   . GLU B 1 280 ? -22.038 -43.589 -6.494  1.00 39.66  ? 280 GLU B N   1 
ATOM   5805  C CA  . GLU B 1 280 ? -23.289 -44.246 -6.849  1.00 47.19  ? 280 GLU B CA  1 
ATOM   5806  C C   . GLU B 1 280 ? -23.369 -45.624 -6.200  1.00 40.07  ? 280 GLU B C   1 
ATOM   5807  O O   . GLU B 1 280 ? -24.455 -46.019 -5.785  1.00 34.48  ? 280 GLU B O   1 
ATOM   5808  C CB  . GLU B 1 280 ? -23.485 -44.408 -8.365  1.00 48.46  ? 280 GLU B CB  1 
ATOM   5809  C CG  . GLU B 1 280 ? -23.666 -43.081 -9.110  1.00 56.28  ? 280 GLU B CG  1 
ATOM   5810  C CD  . GLU B 1 280 ? -23.511 -43.153 -10.626 1.00 63.28  ? 280 GLU B CD  1 
ATOM   5811  O OE1 . GLU B 1 280 ? -23.427 -42.067 -11.269 1.00 62.00  ? 280 GLU B OE1 1 
ATOM   5812  O OE2 . GLU B 1 280 ? -23.508 -44.293 -11.171 1.00 72.93  ? 280 GLU B OE2 1 
ATOM   5813  N N   . VAL B 1 281 ? -22.243 -46.355 -6.171  1.00 37.94  ? 281 VAL B N   1 
ATOM   5814  C CA  . VAL B 1 281 ? -22.187 -47.643 -5.491  1.00 38.59  ? 281 VAL B CA  1 
ATOM   5815  C C   . VAL B 1 281 ? -22.529 -47.436 -4.029  1.00 37.96  ? 281 VAL B C   1 
ATOM   5816  O O   . VAL B 1 281 ? -23.363 -48.141 -3.474  1.00 34.46  ? 281 VAL B O   1 
ATOM   5817  C CB  . VAL B 1 281 ? -20.821 -48.340 -5.589  1.00 39.41  ? 281 VAL B CB  1 
ATOM   5818  C CG1 . VAL B 1 281 ? -20.691 -49.468 -4.557  1.00 41.17  ? 281 VAL B CG1 1 
ATOM   5819  C CG2 . VAL B 1 281 ? -20.552 -48.840 -6.994  1.00 40.93  ? 281 VAL B CG2 1 
ATOM   5820  N N   . LEU B 1 282 ? -21.888 -46.447 -3.410  1.00 35.79  ? 282 LEU B N   1 
ATOM   5821  C CA  . LEU B 1 282 ? -22.055 -46.261 -1.973  1.00 37.50  ? 282 LEU B CA  1 
ATOM   5822  C C   . LEU B 1 282 ? -23.509 -45.930 -1.625  1.00 38.08  ? 282 LEU B C   1 
ATOM   5823  O O   . LEU B 1 282 ? -24.066 -46.486 -0.674  1.00 34.24  ? 282 LEU B O   1 
ATOM   5824  C CB  . LEU B 1 282 ? -21.102 -45.190 -1.442  1.00 35.36  ? 282 LEU B CB  1 
ATOM   5825  C CG  . LEU B 1 282 ? -21.267 -44.873 0.045   1.00 38.30  ? 282 LEU B CG  1 
ATOM   5826  C CD1 . LEU B 1 282 ? -21.176 -46.155 0.896   1.00 36.54  ? 282 LEU B CD1 1 
ATOM   5827  C CD2 . LEU B 1 282 ? -20.243 -43.853 0.488   1.00 42.18  ? 282 LEU B CD2 1 
ATOM   5828  N N   . ARG B 1 283 ? -24.115 -45.018 -2.386  1.00 36.30  ? 283 ARG B N   1 
ATOM   5829  C CA  . ARG B 1 283 ? -25.500 -44.626 -2.168  1.00 40.77  ? 283 ARG B CA  1 
ATOM   5830  C C   . ARG B 1 283 ? -26.428 -45.828 -2.361  1.00 41.65  ? 283 ARG B C   1 
ATOM   5831  O O   . ARG B 1 283 ? -27.446 -45.918 -1.698  1.00 38.97  ? 283 ARG B O   1 
ATOM   5832  C CB  . ARG B 1 283 ? -25.857 -43.502 -3.140  1.00 41.95  ? 283 ARG B CB  1 
ATOM   5833  C CG  . ARG B 1 283 ? -25.324 -42.138 -2.719  1.00 45.68  ? 283 ARG B CG  1 
ATOM   5834  C CD  . ARG B 1 283 ? -25.854 -41.141 -3.724  1.00 52.30  ? 283 ARG B CD  1 
ATOM   5835  N NE  . ARG B 1 283 ? -25.157 -39.871 -3.719  1.00 53.23  ? 283 ARG B NE  1 
ATOM   5836  C CZ  . ARG B 1 283 ? -25.440 -38.863 -2.908  1.00 60.41  ? 283 ARG B CZ  1 
ATOM   5837  N NH1 . ARG B 1 283 ? -26.340 -39.003 -1.954  1.00 60.53  ? 283 ARG B NH1 1 
ATOM   5838  N NH2 . ARG B 1 283 ? -24.810 -37.712 -3.045  1.00 57.68  ? 283 ARG B NH2 1 
ATOM   5839  N N   . TRP B 1 284 ? -26.083 -46.742 -3.285  1.00 38.28  ? 284 TRP B N   1 
ATOM   5840  C CA  . TRP B 1 284 ? -26.883 -47.950 -3.500  1.00 39.31  ? 284 TRP B CA  1 
ATOM   5841  C C   . TRP B 1 284 ? -26.803 -48.868 -2.272  1.00 38.79  ? 284 TRP B C   1 
ATOM   5842  O O   . TRP B 1 284 ? -27.814 -49.381 -1.801  1.00 40.04  ? 284 TRP B O   1 
ATOM   5843  C CB  . TRP B 1 284 ? -26.408 -48.674 -4.769  1.00 36.09  ? 284 TRP B CB  1 
ATOM   5844  C CG  . TRP B 1 284 ? -27.246 -49.829 -5.216  1.00 43.10  ? 284 TRP B CG  1 
ATOM   5845  C CD1 . TRP B 1 284 ? -28.451 -49.763 -5.851  1.00 45.00  ? 284 TRP B CD1 1 
ATOM   5846  C CD2 . TRP B 1 284 ? -26.934 -51.230 -5.063  1.00 41.90  ? 284 TRP B CD2 1 
ATOM   5847  N NE1 . TRP B 1 284 ? -28.877 -51.026 -6.160  1.00 47.08  ? 284 TRP B NE1 1 
ATOM   5848  C CE2 . TRP B 1 284 ? -27.974 -51.945 -5.689  1.00 46.93  ? 284 TRP B CE2 1 
ATOM   5849  C CE3 . TRP B 1 284 ? -25.846 -51.946 -4.546  1.00 43.68  ? 284 TRP B CE3 1 
ATOM   5850  C CZ2 . TRP B 1 284 ? -27.981 -53.339 -5.745  1.00 45.09  ? 284 TRP B CZ2 1 
ATOM   5851  C CZ3 . TRP B 1 284 ? -25.846 -53.325 -4.616  1.00 45.77  ? 284 TRP B CZ3 1 
ATOM   5852  C CH2 . TRP B 1 284 ? -26.907 -54.011 -5.198  1.00 46.27  ? 284 TRP B CH2 1 
ATOM   5853  N N   . ILE B 1 285 ? -25.580 -49.089 -1.762  1.00 40.09  ? 285 ILE B N   1 
ATOM   5854  C CA  . ILE B 1 285 ? -25.375 -49.906 -0.568  1.00 40.46  ? 285 ILE B CA  1 
ATOM   5855  C C   . ILE B 1 285 ? -26.237 -49.331 0.566   1.00 43.35  ? 285 ILE B C   1 
ATOM   5856  O O   . ILE B 1 285 ? -26.977 -50.065 1.241   1.00 39.19  ? 285 ILE B O   1 
ATOM   5857  C CB  . ILE B 1 285 ? -23.873 -49.989 -0.187  1.00 39.95  ? 285 ILE B CB  1 
ATOM   5858  C CG1 . ILE B 1 285 ? -23.030 -50.748 -1.216  1.00 36.69  ? 285 ILE B CG1 1 
ATOM   5859  C CG2 . ILE B 1 285 ? -23.678 -50.556 1.220   1.00 37.22  ? 285 ILE B CG2 1 
ATOM   5860  C CD1 . ILE B 1 285 ? -23.351 -52.213 -1.332  1.00 39.22  ? 285 ILE B CD1 1 
ATOM   5861  N N   . GLN B 1 286 ? -26.150 -48.004 0.746   1.00 39.95  ? 286 GLN B N   1 
ATOM   5862  C CA  . GLN B 1 286 ? -26.884 -47.300 1.791   1.00 40.62  ? 286 GLN B CA  1 
ATOM   5863  C C   . GLN B 1 286 ? -28.392 -47.449 1.562   1.00 44.88  ? 286 GLN B C   1 
ATOM   5864  O O   . GLN B 1 286 ? -29.117 -47.566 2.536   1.00 39.33  ? 286 GLN B O   1 
ATOM   5865  C CB  . GLN B 1 286 ? -26.475 -45.825 1.869   1.00 42.91  ? 286 GLN B CB  1 
ATOM   5866  C CG  . GLN B 1 286 ? -25.089 -45.609 2.474   1.00 44.50  ? 286 GLN B CG  1 
ATOM   5867  C CD  . GLN B 1 286 ? -24.580 -44.189 2.377   1.00 43.03  ? 286 GLN B CD  1 
ATOM   5868  O OE1 . GLN B 1 286 ? -24.089 -43.622 3.351   1.00 50.32  ? 286 GLN B OE1 1 
ATOM   5869  N NE2 . GLN B 1 286 ? -24.657 -43.608 1.189   1.00 38.04  ? 286 GLN B NE2 1 
ATOM   5870  N N   . MET B 1 287 ? -28.859 -47.436 0.303   1.00 38.95  ? 287 MET B N   1 
ATOM   5871  C CA  . MET B 1 287 ? -30.280 -47.628 0.002   1.00 47.35  ? 287 MET B CA  1 
ATOM   5872  C C   . MET B 1 287 ? -30.742 -49.035 0.430   1.00 47.51  ? 287 MET B C   1 
ATOM   5873  O O   . MET B 1 287 ? -31.860 -49.196 0.905   1.00 45.12  ? 287 MET B O   1 
ATOM   5874  C CB  . MET B 1 287 ? -30.569 -47.398 -1.492  1.00 44.16  ? 287 MET B CB  1 
ATOM   5875  C CG  . MET B 1 287 ? -31.960 -47.852 -1.979  1.00 49.26  ? 287 MET B CG  1 
ATOM   5876  S SD  . MET B 1 287 ? -32.078 -49.641 -2.406  1.00 49.34  ? 287 MET B SD  1 
ATOM   5877  C CE  . MET B 1 287 ? -31.018 -49.773 -3.853  1.00 48.31  ? 287 MET B CE  1 
ATOM   5878  N N   . LEU B 1 288 ? -29.876 -50.049 0.288   1.00 45.09  ? 288 LEU B N   1 
ATOM   5879  C CA  . LEU B 1 288 ? -30.182 -51.420 0.690   1.00 43.85  ? 288 LEU B CA  1 
ATOM   5880  C C   . LEU B 1 288 ? -30.304 -51.554 2.207   1.00 47.11  ? 288 LEU B C   1 
ATOM   5881  O O   . LEU B 1 288 ? -31.211 -52.234 2.702   1.00 43.05  ? 288 LEU B O   1 
ATOM   5882  C CB  . LEU B 1 288 ? -29.071 -52.356 0.198   1.00 42.96  ? 288 LEU B CB  1 
ATOM   5883  C CG  . LEU B 1 288 ? -29.128 -52.724 -1.283  1.00 43.08  ? 288 LEU B CG  1 
ATOM   5884  C CD1 . LEU B 1 288 ? -27.919 -53.561 -1.662  1.00 46.25  ? 288 LEU B CD1 1 
ATOM   5885  C CD2 . LEU B 1 288 ? -30.427 -53.466 -1.620  1.00 49.73  ? 288 LEU B CD2 1 
ATOM   5886  N N   . TYR B 1 289 ? -29.340 -50.964 2.927   1.00 45.91  ? 289 TYR B N   1 
ATOM   5887  C CA  . TYR B 1 289 ? -29.378 -50.914 4.383   1.00 49.94  ? 289 TYR B CA  1 
ATOM   5888  C C   . TYR B 1 289 ? -30.731 -50.361 4.857   1.00 52.92  ? 289 TYR B C   1 
ATOM   5889  O O   . TYR B 1 289 ? -31.342 -50.925 5.748   1.00 50.40  ? 289 TYR B O   1 
ATOM   5890  C CB  . TYR B 1 289 ? -28.181 -50.127 4.929   1.00 51.69  ? 289 TYR B CB  1 
ATOM   5891  C CG  . TYR B 1 289 ? -28.032 -50.158 6.434   1.00 56.44  ? 289 TYR B CG  1 
ATOM   5892  C CD1 . TYR B 1 289 ? -28.722 -49.270 7.253   1.00 59.92  ? 289 TYR B CD1 1 
ATOM   5893  C CD2 . TYR B 1 289 ? -27.238 -51.111 7.047   1.00 59.43  ? 289 TYR B CD2 1 
ATOM   5894  C CE1 . TYR B 1 289 ? -28.608 -49.313 8.635   1.00 58.26  ? 289 TYR B CE1 1 
ATOM   5895  C CE2 . TYR B 1 289 ? -27.114 -51.172 8.426   1.00 62.59  ? 289 TYR B CE2 1 
ATOM   5896  C CZ  . TYR B 1 289 ? -27.796 -50.269 9.221   1.00 61.26  ? 289 TYR B CZ  1 
ATOM   5897  O OH  . TYR B 1 289 ? -27.639 -50.343 10.577  1.00 65.70  ? 289 TYR B OH  1 
ATOM   5898  N N   . LYS B 1 290 ? -31.193 -49.254 4.270   1.00 49.34  ? 290 LYS B N   1 
ATOM   5899  C CA  . LYS B 1 290 ? -32.399 -48.578 4.731   1.00 54.87  ? 290 LYS B CA  1 
ATOM   5900  C C   . LYS B 1 290 ? -33.634 -49.367 4.291   1.00 51.60  ? 290 LYS B C   1 
ATOM   5901  O O   . LYS B 1 290 ? -34.603 -49.463 5.033   1.00 61.74  ? 290 LYS B O   1 
ATOM   5902  C CB  . LYS B 1 290 ? -32.435 -47.160 4.156   1.00 58.07  ? 290 LYS B CB  1 
ATOM   5903  C CG  . LYS B 1 290 ? -33.569 -46.274 4.636   1.00 59.98  ? 290 LYS B CG  1 
ATOM   5904  C CD  . LYS B 1 290 ? -33.696 -44.982 3.829   1.00 65.13  ? 290 LYS B CD  1 
ATOM   5905  C CE  . LYS B 1 290 ? -34.746 -44.039 4.386   1.00 67.74  ? 290 LYS B CE  1 
ATOM   5906  N NZ  . LYS B 1 290 ? -35.130 -42.995 3.404   1.00 76.58  ? 290 LYS B NZ  1 
ATOM   5907  N N   . LYS B 1 291 ? -33.593 -49.929 3.079   1.00 49.34  ? 291 LYS B N   1 
ATOM   5908  C CA  . LYS B 1 291 ? -34.698 -50.720 2.564   1.00 55.69  ? 291 LYS B CA  1 
ATOM   5909  C C   . LYS B 1 291 ? -34.933 -51.951 3.437   1.00 55.38  ? 291 LYS B C   1 
ATOM   5910  O O   . LYS B 1 291 ? -36.067 -52.374 3.590   1.00 62.68  ? 291 LYS B O   1 
ATOM   5911  C CB  . LYS B 1 291 ? -34.445 -51.140 1.115   1.00 56.60  ? 291 LYS B CB  1 
ATOM   5912  C CG  . LYS B 1 291 ? -35.601 -51.856 0.435   1.00 55.70  ? 291 LYS B CG  1 
ATOM   5913  C CD  . LYS B 1 291 ? -35.423 -52.016 -1.059  1.00 56.41  ? 291 LYS B CD  1 
ATOM   5914  C CE  . LYS B 1 291 ? -36.437 -52.949 -1.690  1.00 62.85  ? 291 LYS B CE  1 
ATOM   5915  N NZ  . LYS B 1 291 ? -37.810 -52.420 -1.548  1.00 60.14  ? 291 LYS B NZ  1 
ATOM   5916  N N   . PHE B 1 292 ? -33.873 -52.526 4.006   1.00 53.93  ? 292 PHE B N   1 
ATOM   5917  C CA  . PHE B 1 292 ? -33.997 -53.810 4.682   1.00 57.19  ? 292 PHE B CA  1 
ATOM   5918  C C   . PHE B 1 292 ? -33.828 -53.663 6.194   1.00 53.91  ? 292 PHE B C   1 
ATOM   5919  O O   . PHE B 1 292 ? -33.715 -54.675 6.878   1.00 54.72  ? 292 PHE B O   1 
ATOM   5920  C CB  . PHE B 1 292 ? -33.041 -54.830 4.047   1.00 53.79  ? 292 PHE B CB  1 
ATOM   5921  C CG  . PHE B 1 292 ? -33.478 -55.269 2.671   1.00 52.61  ? 292 PHE B CG  1 
ATOM   5922  C CD1 . PHE B 1 292 ? -34.684 -55.941 2.495   1.00 53.21  ? 292 PHE B CD1 1 
ATOM   5923  C CD2 . PHE B 1 292 ? -32.728 -54.958 1.548   1.00 44.88  ? 292 PHE B CD2 1 
ATOM   5924  C CE1 . PHE B 1 292 ? -35.109 -56.337 1.236   1.00 51.08  ? 292 PHE B CE1 1 
ATOM   5925  C CE2 . PHE B 1 292 ? -33.147 -55.358 0.285   1.00 53.81  ? 292 PHE B CE2 1 
ATOM   5926  C CZ  . PHE B 1 292 ? -34.331 -56.058 0.128   1.00 57.12  ? 292 PHE B CZ  1 
ATOM   5927  N N   . GLY B 1 293 ? -33.836 -52.418 6.703   1.00 50.30  ? 293 GLY B N   1 
ATOM   5928  C CA  . GLY B 1 293 ? -33.683 -52.153 8.126   1.00 50.78  ? 293 GLY B CA  1 
ATOM   5929  C C   . GLY B 1 293 ? -32.392 -52.739 8.698   1.00 51.95  ? 293 GLY B C   1 
ATOM   5930  O O   . GLY B 1 293 ? -32.332 -53.090 9.874   1.00 57.03  ? 293 GLY B O   1 
ATOM   5931  N N   . GLY B 1 294 ? -31.347 -52.849 7.869   1.00 51.44  ? 294 GLY B N   1 
ATOM   5932  C CA  . GLY B 1 294 ? -30.098 -53.481 8.286   1.00 45.76  ? 294 GLY B CA  1 
ATOM   5933  C C   . GLY B 1 294 ? -29.526 -54.338 7.162   1.00 45.25  ? 294 GLY B C   1 
ATOM   5934  O O   . GLY B 1 294 ? -29.974 -54.237 6.021   1.00 46.00  ? 294 GLY B O   1 
ATOM   5935  N N   . VAL B 1 295 ? -28.561 -55.200 7.494   1.00 46.99  ? 295 VAL B N   1 
ATOM   5936  C CA  . VAL B 1 295 ? -27.976 -56.067 6.486   1.00 52.73  ? 295 VAL B CA  1 
ATOM   5937  C C   . VAL B 1 295 ? -29.087 -56.971 5.953   1.00 58.19  ? 295 VAL B C   1 
ATOM   5938  O O   . VAL B 1 295 ? -29.772 -57.621 6.738   1.00 56.52  ? 295 VAL B O   1 
ATOM   5939  C CB  . VAL B 1 295 ? -26.800 -56.894 7.040   1.00 54.54  ? 295 VAL B CB  1 
ATOM   5940  C CG1 . VAL B 1 295 ? -26.184 -57.786 5.960   1.00 53.87  ? 295 VAL B CG1 1 
ATOM   5941  C CG2 . VAL B 1 295 ? -25.743 -56.021 7.695   1.00 51.17  ? 295 VAL B CG2 1 
ATOM   5942  N N   . PRO B 1 296 ? -29.329 -57.036 4.621   1.00 53.40  ? 296 PRO B N   1 
ATOM   5943  C CA  . PRO B 1 296 ? -30.294 -57.992 4.089   1.00 53.13  ? 296 PRO B CA  1 
ATOM   5944  C C   . PRO B 1 296 ? -29.735 -59.412 4.155   1.00 52.36  ? 296 PRO B C   1 
ATOM   5945  O O   . PRO B 1 296 ? -28.520 -59.635 4.105   1.00 50.55  ? 296 PRO B O   1 
ATOM   5946  C CB  . PRO B 1 296 ? -30.541 -57.535 2.647   1.00 53.57  ? 296 PRO B CB  1 
ATOM   5947  C CG  . PRO B 1 296 ? -29.273 -56.785 2.265   1.00 55.73  ? 296 PRO B CG  1 
ATOM   5948  C CD  . PRO B 1 296 ? -28.711 -56.225 3.563   1.00 54.97  ? 296 PRO B CD  1 
ATOM   5949  N N   . THR B 1 297 ? -30.663 -60.362 4.244   1.00 48.07  ? 297 THR B N   1 
ATOM   5950  C CA  . THR B 1 297 ? -30.365 -61.777 4.107   1.00 49.08  ? 297 THR B CA  1 
ATOM   5951  C C   . THR B 1 297 ? -29.988 -62.080 2.655   1.00 53.44  ? 297 THR B C   1 
ATOM   5952  O O   . THR B 1 297 ? -30.304 -61.303 1.739   1.00 44.52  ? 297 THR B O   1 
ATOM   5953  C CB  . THR B 1 297 ? -31.579 -62.643 4.482   1.00 49.24  ? 297 THR B CB  1 
ATOM   5954  O OG1 . THR B 1 297 ? -32.568 -62.464 3.457   1.00 47.77  ? 297 THR B OG1 1 
ATOM   5955  C CG2 . THR B 1 297 ? -32.147 -62.303 5.842   1.00 46.66  ? 297 THR B CG2 1 
ATOM   5956  N N   . LYS B 1 298 ? -29.374 -63.257 2.480   1.00 49.15  ? 298 LYS B N   1 
ATOM   5957  C CA  . LYS B 1 298 ? -28.961 -63.766 1.184   1.00 54.66  ? 298 LYS B CA  1 
ATOM   5958  C C   . LYS B 1 298 ? -30.173 -63.848 0.248   1.00 56.56  ? 298 LYS B C   1 
ATOM   5959  O O   . LYS B 1 298 ? -30.076 -63.465 -0.927  1.00 51.74  ? 298 LYS B O   1 
ATOM   5960  C CB  . LYS B 1 298 ? -28.205 -65.084 1.414   1.00 54.21  ? 298 LYS B CB  1 
ATOM   5961  C CG  . LYS B 1 298 ? -27.617 -65.741 0.174   1.00 67.45  ? 298 LYS B CG  1 
ATOM   5962  C CD  . LYS B 1 298 ? -26.740 -66.947 0.486   1.00 75.09  ? 298 LYS B CD  1 
ATOM   5963  C CE  . LYS B 1 298 ? -26.159 -67.614 -0.749  1.00 82.97  ? 298 LYS B CE  1 
ATOM   5964  N NZ  . LYS B 1 298 ? -27.186 -68.348 -1.532  1.00 86.02  ? 298 LYS B NZ  1 
ATOM   5965  N N   . GLU B 1 299 ? -31.327 -64.286 0.779   1.00 46.45  ? 299 GLU B N   1 
ATOM   5966  C CA  . GLU B 1 299 ? -32.535 -64.453 -0.026  1.00 51.91  ? 299 GLU B CA  1 
ATOM   5967  C C   . GLU B 1 299 ? -33.103 -63.090 -0.444  1.00 48.30  ? 299 GLU B C   1 
ATOM   5968  O O   . GLU B 1 299 ? -33.551 -62.915 -1.579  1.00 45.33  ? 299 GLU B O   1 
ATOM   5969  C CB  . GLU B 1 299 ? -33.576 -65.283 0.741   1.00 56.44  ? 299 GLU B CB  1 
ATOM   5970  C CG  . GLU B 1 299 ? -35.005 -65.114 0.229   1.00 68.46  ? 299 GLU B CG  1 
ATOM   5971  C CD  . GLU B 1 299 ? -36.085 -65.720 1.116   1.00 80.73  ? 299 GLU B CD  1 
ATOM   5972  O OE1 . GLU B 1 299 ? -36.185 -66.966 1.156   1.00 78.01  ? 299 GLU B OE1 1 
ATOM   5973  O OE2 . GLU B 1 299 ? -36.805 -64.945 1.789   1.00 82.30  ? 299 GLU B OE2 1 
ATOM   5974  N N   . GLN B 1 300 ? -33.097 -62.103 0.461   1.00 46.41  ? 300 GLN B N   1 
ATOM   5975  C CA  . GLN B 1 300 ? -33.611 -60.784 0.112   1.00 48.16  ? 300 GLN B CA  1 
ATOM   5976  C C   . GLN B 1 300 ? -32.741 -60.131 -0.968  1.00 45.19  ? 300 GLN B C   1 
ATOM   5977  O O   . GLN B 1 300 ? -33.250 -59.427 -1.845  1.00 45.56  ? 300 GLN B O   1 
ATOM   5978  C CB  . GLN B 1 300 ? -33.657 -59.884 1.342   1.00 47.82  ? 300 GLN B CB  1 
ATOM   5979  C CG  . GLN B 1 300 ? -34.729 -60.293 2.339   1.00 50.16  ? 300 GLN B CG  1 
ATOM   5980  C CD  . GLN B 1 300 ? -34.558 -59.569 3.649   1.00 52.25  ? 300 GLN B CD  1 
ATOM   5981  O OE1 . GLN B 1 300 ? -33.448 -59.411 4.170   1.00 54.43  ? 300 GLN B OE1 1 
ATOM   5982  N NE2 . GLN B 1 300 ? -35.669 -59.096 4.184   1.00 52.09  ? 300 GLN B NE2 1 
ATOM   5983  N N   . LEU B 1 301 ? -31.417 -60.313 -0.865  1.00 45.62  ? 301 LEU B N   1 
ATOM   5984  C CA  . LEU B 1 301 ? -30.515 -59.633 -1.783  1.00 50.29  ? 301 LEU B CA  1 
ATOM   5985  C C   . LEU B 1 301 ? -30.661 -60.279 -3.163  1.00 48.87  ? 301 LEU B C   1 
ATOM   5986  O O   . LEU B 1 301 ? -30.775 -59.563 -4.159  1.00 51.57  ? 301 LEU B O   1 
ATOM   5987  C CB  . LEU B 1 301 ? -29.067 -59.667 -1.261  1.00 48.94  ? 301 LEU B CB  1 
ATOM   5988  C CG  . LEU B 1 301 ? -28.035 -58.933 -2.130  1.00 51.80  ? 301 LEU B CG  1 
ATOM   5989  C CD1 . LEU B 1 301 ? -28.412 -57.459 -2.321  1.00 54.56  ? 301 LEU B CD1 1 
ATOM   5990  C CD2 . LEU B 1 301 ? -26.628 -59.062 -1.545  1.00 53.44  ? 301 LEU B CD2 1 
ATOM   5991  N N   . GLU B 1 302 ? -30.739 -61.622 -3.197  1.00 52.72  ? 302 GLU B N   1 
ATOM   5992  C CA  . GLU B 1 302 ? -31.020 -62.364 -4.423  1.00 54.78  ? 302 GLU B CA  1 
ATOM   5993  C C   . GLU B 1 302 ? -32.265 -61.830 -5.137  1.00 55.29  ? 302 GLU B C   1 
ATOM   5994  O O   . GLU B 1 302 ? -32.243 -61.573 -6.344  1.00 53.49  ? 302 GLU B O   1 
ATOM   5995  C CB  . GLU B 1 302 ? -31.197 -63.855 -4.133  1.00 58.11  ? 302 GLU B CB  1 
ATOM   5996  C CG  . GLU B 1 302 ? -29.890 -64.616 -3.994  1.00 66.26  ? 302 GLU B CG  1 
ATOM   5997  C CD  . GLU B 1 302 ? -30.045 -66.044 -3.485  1.00 78.70  ? 302 GLU B CD  1 
ATOM   5998  O OE1 . GLU B 1 302 ? -31.010 -66.716 -3.903  1.00 83.79  ? 302 GLU B OE1 1 
ATOM   5999  O OE2 . GLU B 1 302 ? -29.191 -66.493 -2.688  1.00 81.12  ? 302 GLU B OE2 1 
ATOM   6000  N N   . ARG B 1 303 ? -33.354 -61.649 -4.389  1.00 53.53  ? 303 ARG B N   1 
ATOM   6001  C CA  . ARG B 1 303 ? -34.623 -61.278 -4.996  1.00 58.60  ? 303 ARG B CA  1 
ATOM   6002  C C   . ARG B 1 303 ? -34.532 -59.850 -5.527  1.00 51.82  ? 303 ARG B C   1 
ATOM   6003  O O   . ARG B 1 303 ? -34.959 -59.582 -6.651  1.00 46.01  ? 303 ARG B O   1 
ATOM   6004  C CB  . ARG B 1 303 ? -35.742 -61.485 -3.974  1.00 68.54  ? 303 ARG B CB  1 
ATOM   6005  C CG  . ARG B 1 303 ? -37.117 -60.967 -4.371  1.00 75.97  ? 303 ARG B CG  1 
ATOM   6006  C CD  . ARG B 1 303 ? -38.118 -61.484 -3.345  1.00 85.17  ? 303 ARG B CD  1 
ATOM   6007  N NE  . ARG B 1 303 ? -39.023 -60.469 -2.807  1.00 95.77  ? 303 ARG B NE  1 
ATOM   6008  C CZ  . ARG B 1 303 ? -38.998 -60.001 -1.555  1.00 97.88  ? 303 ARG B CZ  1 
ATOM   6009  N NH1 . ARG B 1 303 ? -38.008 -60.319 -0.732  1.00 90.84  ? 303 ARG B NH1 1 
ATOM   6010  N NH2 . ARG B 1 303 ? -39.953 -59.181 -1.139  1.00 93.66  ? 303 ARG B NH2 1 
ATOM   6011  N N   . PHE B 1 304 ? -33.976 -58.943 -4.707  1.00 53.22  ? 304 PHE B N   1 
ATOM   6012  C CA  . PHE B 1 304 ? -33.802 -57.560 -5.111  1.00 51.58  ? 304 PHE B CA  1 
ATOM   6013  C C   . PHE B 1 304 ? -32.938 -57.483 -6.378  1.00 52.46  ? 304 PHE B C   1 
ATOM   6014  O O   . PHE B 1 304 ? -33.209 -56.669 -7.260  1.00 56.99  ? 304 PHE B O   1 
ATOM   6015  C CB  . PHE B 1 304 ? -33.227 -56.731 -3.957  1.00 56.83  ? 304 PHE B CB  1 
ATOM   6016  C CG  . PHE B 1 304 ? -33.115 -55.257 -4.271  1.00 62.27  ? 304 PHE B CG  1 
ATOM   6017  C CD1 . PHE B 1 304 ? -34.227 -54.428 -4.192  1.00 59.09  ? 304 PHE B CD1 1 
ATOM   6018  C CD2 . PHE B 1 304 ? -31.917 -54.706 -4.719  1.00 62.28  ? 304 PHE B CD2 1 
ATOM   6019  C CE1 . PHE B 1 304 ? -34.128 -53.076 -4.493  1.00 58.63  ? 304 PHE B CE1 1 
ATOM   6020  C CE2 . PHE B 1 304 ? -31.830 -53.354 -5.038  1.00 56.67  ? 304 PHE B CE2 1 
ATOM   6021  C CZ  . PHE B 1 304 ? -32.936 -52.544 -4.916  1.00 53.38  ? 304 PHE B CZ  1 
ATOM   6022  N N   . ALA B 1 305 ? -31.899 -58.327 -6.472  1.00 47.77  ? 305 ALA B N   1 
ATOM   6023  C CA  . ALA B 1 305 ? -31.022 -58.353 -7.636  1.00 50.78  ? 305 ALA B CA  1 
ATOM   6024  C C   . ALA B 1 305 ? -31.755 -58.860 -8.884  1.00 51.52  ? 305 ALA B C   1 
ATOM   6025  O O   . ALA B 1 305 ? -31.543 -58.318 -9.973  1.00 52.33  ? 305 ALA B O   1 
ATOM   6026  C CB  . ALA B 1 305 ? -29.783 -59.184 -7.377  1.00 48.31  ? 305 ALA B CB  1 
ATOM   6027  N N   . TRP B 1 306 ? -32.535 -59.945 -8.745  1.00 47.03  ? 306 TRP B N   1 
ATOM   6028  C CA  . TRP B 1 306 ? -33.360 -60.433 -9.843  1.00 51.13  ? 306 TRP B CA  1 
ATOM   6029  C C   . TRP B 1 306 ? -34.327 -59.338 -10.307 1.00 46.49  ? 306 TRP B C   1 
ATOM   6030  O O   . TRP B 1 306 ? -34.448 -59.102 -11.508 1.00 48.86  ? 306 TRP B O   1 
ATOM   6031  C CB  . TRP B 1 306 ? -34.109 -61.729 -9.472  1.00 47.68  ? 306 TRP B CB  1 
ATOM   6032  C CG  . TRP B 1 306 ? -33.276 -62.968 -9.578  1.00 47.82  ? 306 TRP B CG  1 
ATOM   6033  C CD1 . TRP B 1 306 ? -32.819 -63.738 -8.540  1.00 53.77  ? 306 TRP B CD1 1 
ATOM   6034  C CD2 . TRP B 1 306 ? -32.802 -63.598 -10.786 1.00 52.57  ? 306 TRP B CD2 1 
ATOM   6035  N NE1 . TRP B 1 306 ? -32.081 -64.791 -9.014  1.00 53.03  ? 306 TRP B NE1 1 
ATOM   6036  C CE2 . TRP B 1 306 ? -32.059 -64.736 -10.389 1.00 53.73  ? 306 TRP B CE2 1 
ATOM   6037  C CE3 . TRP B 1 306 ? -32.940 -63.325 -12.156 1.00 50.90  ? 306 TRP B CE3 1 
ATOM   6038  C CZ2 . TRP B 1 306 ? -31.464 -65.594 -11.318 1.00 55.10  ? 306 TRP B CZ2 1 
ATOM   6039  C CZ3 . TRP B 1 306 ? -32.344 -64.168 -13.068 1.00 52.45  ? 306 TRP B CZ3 1 
ATOM   6040  C CH2 . TRP B 1 306 ? -31.616 -65.288 -12.652 1.00 54.86  ? 306 TRP B CH2 1 
ATOM   6041  N N   . ASP B 1 307 ? -34.993 -58.669 -9.357  1.00 51.50  ? 307 ASP B N   1 
ATOM   6042  C CA  . ASP B 1 307 ? -35.945 -57.611 -9.672  1.00 56.22  ? 307 ASP B CA  1 
ATOM   6043  C C   . ASP B 1 307 ? -35.265 -56.532 -10.511 1.00 66.60  ? 307 ASP B C   1 
ATOM   6044  O O   . ASP B 1 307 ? -35.836 -56.088 -11.509 1.00 66.44  ? 307 ASP B O   1 
ATOM   6045  C CB  . ASP B 1 307 ? -36.526 -56.966 -8.410  1.00 58.81  ? 307 ASP B CB  1 
ATOM   6046  C CG  . ASP B 1 307 ? -37.547 -57.825 -7.672  1.00 72.41  ? 307 ASP B CG  1 
ATOM   6047  O OD1 . ASP B 1 307 ? -37.919 -58.893 -8.214  1.00 68.80  ? 307 ASP B OD1 1 
ATOM   6048  O OD2 . ASP B 1 307 ? -37.972 -57.420 -6.550  1.00 64.90  ? 307 ASP B OD2 1 
ATOM   6049  N N   . THR B 1 308 ? -34.049 -56.121 -10.091 1.00 51.37  ? 308 THR B N   1 
ATOM   6050  C CA  . THR B 1 308 ? -33.294 -55.091 -10.788 1.00 49.40  ? 308 THR B CA  1 
ATOM   6051  C C   . THR B 1 308 ? -32.932 -55.521 -12.210 1.00 48.17  ? 308 THR B C   1 
ATOM   6052  O O   . THR B 1 308 ? -33.118 -54.742 -13.137 1.00 55.61  ? 308 THR B O   1 
ATOM   6053  C CB  . THR B 1 308 ? -32.016 -54.703 -10.024 1.00 50.33  ? 308 THR B CB  1 
ATOM   6054  O OG1 . THR B 1 308 ? -32.343 -54.385 -8.669  1.00 49.90  ? 308 THR B OG1 1 
ATOM   6055  C CG2 . THR B 1 308 ? -31.301 -53.526 -10.656 1.00 53.21  ? 308 THR B CG2 1 
ATOM   6056  N N   . LEU B 1 309 ? -32.381 -56.733 -12.372 1.00 51.02  ? 309 LEU B N   1 
ATOM   6057  C CA  . LEU B 1 309 ? -31.860 -57.192 -13.657 1.00 54.10  ? 309 LEU B CA  1 
ATOM   6058  C C   . LEU B 1 309 ? -32.990 -57.490 -14.654 1.00 61.41  ? 309 LEU B C   1 
ATOM   6059  O O   . LEU B 1 309 ? -32.824 -57.287 -15.860 1.00 59.02  ? 309 LEU B O   1 
ATOM   6060  C CB  . LEU B 1 309 ? -31.012 -58.452 -13.455 1.00 52.11  ? 309 LEU B CB  1 
ATOM   6061  C CG  . LEU B 1 309 ? -29.651 -58.294 -12.778 1.00 54.17  ? 309 LEU B CG  1 
ATOM   6062  C CD1 . LEU B 1 309 ? -29.118 -59.655 -12.359 1.00 52.28  ? 309 LEU B CD1 1 
ATOM   6063  C CD2 . LEU B 1 309 ? -28.643 -57.596 -13.697 1.00 59.97  ? 309 LEU B CD2 1 
ATOM   6064  N N   . ASN B 1 310 ? -34.112 -58.040 -14.167 1.00 66.58  ? 310 ASN B N   1 
ATOM   6065  C CA  . ASN B 1 310 ? -35.235 -58.384 -15.029 1.00 71.69  ? 310 ASN B CA  1 
ATOM   6066  C C   . ASN B 1 310 ? -35.932 -57.114 -15.507 1.00 71.76  ? 310 ASN B C   1 
ATOM   6067  O O   . ASN B 1 310 ? -36.530 -57.121 -16.579 1.00 63.25  ? 310 ASN B O   1 
ATOM   6068  C CB  . ASN B 1 310 ? -36.260 -59.288 -14.341 1.00 70.12  ? 310 ASN B CB  1 
ATOM   6069  C CG  . ASN B 1 310 ? -35.750 -60.688 -14.076 1.00 73.74  ? 310 ASN B CG  1 
ATOM   6070  O OD1 . ASN B 1 310 ? -34.872 -61.206 -14.774 1.00 66.97  ? 310 ASN B OD1 1 
ATOM   6071  N ND2 . ASN B 1 310 ? -36.331 -61.318 -13.069 1.00 79.72  ? 310 ASN B ND2 1 
ATOM   6072  N N   . SER B 1 311 ? -35.833 -56.038 -14.710 1.00 70.58  ? 311 SER B N   1 
ATOM   6073  C CA  . SER B 1 311 ? -36.397 -54.749 -15.067 1.00 61.41  ? 311 SER B CA  1 
ATOM   6074  C C   . SER B 1 311 ? -35.403 -53.910 -15.876 1.00 64.20  ? 311 SER B C   1 
ATOM   6075  O O   . SER B 1 311 ? -35.478 -52.690 -15.832 1.00 65.27  ? 311 SER B O   1 
ATOM   6076  C CB  . SER B 1 311 ? -36.861 -54.026 -13.836 1.00 59.31  ? 311 SER B CB  1 
ATOM   6077  O OG  . SER B 1 311 ? -35.768 -53.468 -13.142 1.00 68.56  ? 311 SER B OG  1 
ATOM   6078  N N   . GLY B 1 312 ? -34.473 -54.561 -16.605 1.00 77.97  ? 312 GLY B N   1 
ATOM   6079  C CA  . GLY B 1 312 ? -33.607 -53.909 -17.585 1.00 69.60  ? 312 GLY B CA  1 
ATOM   6080  C C   . GLY B 1 312 ? -32.394 -53.185 -16.984 1.00 74.67  ? 312 GLY B C   1 
ATOM   6081  O O   . GLY B 1 312 ? -31.504 -52.777 -17.730 1.00 64.15  ? 312 GLY B O   1 
ATOM   6082  N N   . GLN B 1 313 ? -32.341 -53.051 -15.645 1.00 77.44  ? 313 GLN B N   1 
ATOM   6083  C CA  . GLN B 1 313 ? -31.341 -52.243 -14.953 1.00 72.01  ? 313 GLN B CA  1 
ATOM   6084  C C   . GLN B 1 313 ? -30.110 -53.078 -14.595 1.00 69.50  ? 313 GLN B C   1 
ATOM   6085  O O   . GLN B 1 313 ? -30.172 -54.318 -14.534 1.00 57.00  ? 313 GLN B O   1 
ATOM   6086  C CB  . GLN B 1 313 ? -31.904 -51.666 -13.651 1.00 72.33  ? 313 GLN B CB  1 
ATOM   6087  C CG  . GLN B 1 313 ? -33.156 -50.824 -13.831 1.00 79.82  ? 313 GLN B CG  1 
ATOM   6088  C CD  . GLN B 1 313 ? -32.871 -49.478 -14.453 1.00 90.15  ? 313 GLN B CD  1 
ATOM   6089  O OE1 . GLN B 1 313 ? -32.873 -48.448 -13.784 1.00 100.73 ? 313 GLN B OE1 1 
ATOM   6090  N NE2 . GLN B 1 313 ? -32.621 -49.473 -15.751 1.00 90.22  ? 313 GLN B NE2 1 
ATOM   6091  N N   . VAL B 1 314 ? -29.001 -52.372 -14.305 1.00 58.75  ? 314 VAL B N   1 
ATOM   6092  C CA  . VAL B 1 314 ? -27.776 -53.038 -13.891 1.00 59.33  ? 314 VAL B CA  1 
ATOM   6093  C C   . VAL B 1 314 ? -27.516 -52.794 -12.402 1.00 57.02  ? 314 VAL B C   1 
ATOM   6094  O O   . VAL B 1 314 ? -28.123 -51.936 -11.755 1.00 50.19  ? 314 VAL B O   1 
ATOM   6095  C CB  . VAL B 1 314 ? -26.571 -52.607 -14.744 1.00 62.15  ? 314 VAL B CB  1 
ATOM   6096  C CG1 . VAL B 1 314 ? -26.801 -52.908 -16.215 1.00 67.41  ? 314 VAL B CG1 1 
ATOM   6097  C CG2 . VAL B 1 314 ? -26.215 -51.145 -14.525 1.00 63.55  ? 314 VAL B CG2 1 
ATOM   6098  N N   . ILE B 1 315 ? -26.563 -53.568 -11.872 1.00 51.65  ? 315 ILE B N   1 
ATOM   6099  C CA  . ILE B 1 315 ? -26.143 -53.435 -10.487 1.00 50.54  ? 315 ILE B CA  1 
ATOM   6100  C C   . ILE B 1 315 ? -24.840 -52.629 -10.443 1.00 50.90  ? 315 ILE B C   1 
ATOM   6101  O O   . ILE B 1 315 ? -23.857 -52.985 -11.091 1.00 44.97  ? 315 ILE B O   1 
ATOM   6102  C CB  . ILE B 1 315 ? -26.040 -54.838 -9.859  1.00 51.76  ? 315 ILE B CB  1 
ATOM   6103  C CG1 . ILE B 1 315 ? -27.453 -55.423 -9.708  1.00 51.94  ? 315 ILE B CG1 1 
ATOM   6104  C CG2 . ILE B 1 315 ? -25.250 -54.803 -8.546  1.00 51.80  ? 315 ILE B CG2 1 
ATOM   6105  C CD1 . ILE B 1 315 ? -27.467 -56.882 -9.461  1.00 61.68  ? 315 ILE B CD1 1 
ATOM   6106  N N   . PRO B 1 316 ? -24.804 -51.494 -9.707  1.00 48.83  ? 316 PRO B N   1 
ATOM   6107  C CA  . PRO B 1 316 ? -23.644 -50.610 -9.726  1.00 40.84  ? 316 PRO B CA  1 
ATOM   6108  C C   . PRO B 1 316 ? -22.421 -51.370 -9.230  1.00 42.79  ? 316 PRO B C   1 
ATOM   6109  O O   . PRO B 1 316 ? -22.498 -52.135 -8.259  1.00 41.32  ? 316 PRO B O   1 
ATOM   6110  C CB  . PRO B 1 316 ? -24.040 -49.461 -8.800  1.00 42.88  ? 316 PRO B CB  1 
ATOM   6111  C CG  . PRO B 1 316 ? -25.551 -49.528 -8.741  1.00 44.72  ? 316 PRO B CG  1 
ATOM   6112  C CD  . PRO B 1 316 ? -25.871 -51.006 -8.821  1.00 47.35  ? 316 PRO B CD  1 
ATOM   6113  N N   . GLY B 1 317 ? -21.328 -51.220 -9.981  1.00 42.12  ? 317 GLY B N   1 
ATOM   6114  C CA  . GLY B 1 317 ? -20.034 -51.762 -9.602  1.00 43.50  ? 317 GLY B CA  1 
ATOM   6115  C C   . GLY B 1 317 ? -19.756 -53.152 -10.155 1.00 40.24  ? 317 GLY B C   1 
ATOM   6116  O O   . GLY B 1 317 ? -18.627 -53.628 -10.029 1.00 39.95  ? 317 GLY B O   1 
ATOM   6117  N N   . TYR B 1 318 ? -20.766 -53.773 -10.785 1.00 39.06  ? 318 TYR B N   1 
ATOM   6118  C CA  . TYR B 1 318 ? -20.643 -55.140 -11.268 1.00 40.41  ? 318 TYR B CA  1 
ATOM   6119  C C   . TYR B 1 318 ? -20.940 -55.275 -12.757 1.00 45.19  ? 318 TYR B C   1 
ATOM   6120  O O   . TYR B 1 318 ? -21.795 -54.572 -13.293 1.00 45.56  ? 318 TYR B O   1 
ATOM   6121  C CB  . TYR B 1 318 ? -21.660 -56.034 -10.575 1.00 44.75  ? 318 TYR B CB  1 
ATOM   6122  C CG  . TYR B 1 318 ? -21.249 -56.476 -9.204  1.00 38.66  ? 318 TYR B CG  1 
ATOM   6123  C CD1 . TYR B 1 318 ? -21.433 -55.654 -8.107  1.00 41.36  ? 318 TYR B CD1 1 
ATOM   6124  C CD2 . TYR B 1 318 ? -20.609 -57.695 -9.020  1.00 38.34  ? 318 TYR B CD2 1 
ATOM   6125  C CE1 . TYR B 1 318 ? -21.051 -56.070 -6.839  1.00 41.86  ? 318 TYR B CE1 1 
ATOM   6126  C CE2 . TYR B 1 318 ? -20.207 -58.112 -7.762  1.00 37.56  ? 318 TYR B CE2 1 
ATOM   6127  C CZ  . TYR B 1 318 ? -20.442 -57.302 -6.669  1.00 38.30  ? 318 TYR B CZ  1 
ATOM   6128  O OH  . TYR B 1 318 ? -20.024 -57.733 -5.446  1.00 42.38  ? 318 TYR B OH  1 
ATOM   6129  N N   . GLY B 1 319 ? -20.285 -56.253 -13.396 1.00 39.29  ? 319 GLY B N   1 
ATOM   6130  C CA  . GLY B 1 319 ? -20.684 -56.688 -14.723 1.00 45.54  ? 319 GLY B CA  1 
ATOM   6131  C C   . GLY B 1 319 ? -20.232 -55.757 -15.857 1.00 52.59  ? 319 GLY B C   1 
ATOM   6132  O O   . GLY B 1 319 ? -20.867 -55.715 -16.904 1.00 57.43  ? 319 GLY B O   1 
ATOM   6133  N N   . HIS B 1 320 ? -19.118 -55.042 -15.668 1.00 53.99  ? 320 HIS B N   1 
ATOM   6134  C CA  . HIS B 1 320 ? -18.522 -54.248 -16.730 1.00 59.19  ? 320 HIS B CA  1 
ATOM   6135  C C   . HIS B 1 320 ? -17.878 -55.155 -17.797 1.00 64.86  ? 320 HIS B C   1 
ATOM   6136  O O   . HIS B 1 320 ? -17.671 -56.355 -17.600 1.00 63.11  ? 320 HIS B O   1 
ATOM   6137  C CB  . HIS B 1 320 ? -17.593 -53.192 -16.113 1.00 64.56  ? 320 HIS B CB  1 
ATOM   6138  C CG  . HIS B 1 320 ? -18.301 -51.995 -15.535 1.00 73.58  ? 320 HIS B CG  1 
ATOM   6139  N ND1 . HIS B 1 320 ? -18.520 -50.826 -16.247 1.00 74.93  ? 320 HIS B ND1 1 
ATOM   6140  C CD2 . HIS B 1 320 ? -18.851 -51.796 -14.321 1.00 72.83  ? 320 HIS B CD2 1 
ATOM   6141  C CE1 . HIS B 1 320 ? -19.159 -49.951 -15.481 1.00 68.42  ? 320 HIS B CE1 1 
ATOM   6142  N NE2 . HIS B 1 320 ? -19.381 -50.522 -14.310 1.00 77.52  ? 320 HIS B NE2 1 
ATOM   6143  N N   . ALA B 1 321 ? -17.514 -54.559 -18.940 1.00 55.77  ? 321 ALA B N   1 
ATOM   6144  C CA  . ALA B 1 321 ? -17.523 -55.269 -20.217 1.00 68.62  ? 321 ALA B CA  1 
ATOM   6145  C C   . ALA B 1 321 ? -16.206 -55.993 -20.482 1.00 70.50  ? 321 ALA B C   1 
ATOM   6146  O O   . ALA B 1 321 ? -16.184 -56.930 -21.270 1.00 67.64  ? 321 ALA B O   1 
ATOM   6147  C CB  . ALA B 1 321 ? -17.824 -54.308 -21.348 1.00 66.70  ? 321 ALA B CB  1 
ATOM   6148  N N   . VAL B 1 322 ? -15.123 -55.557 -19.829 1.00 68.36  ? 322 VAL B N   1 
ATOM   6149  C CA  . VAL B 1 322 ? -13.781 -55.842 -20.313 1.00 72.57  ? 322 VAL B CA  1 
ATOM   6150  C C   . VAL B 1 322 ? -13.207 -57.069 -19.600 1.00 66.10  ? 322 VAL B C   1 
ATOM   6151  O O   . VAL B 1 322 ? -12.742 -58.014 -20.235 1.00 63.20  ? 322 VAL B O   1 
ATOM   6152  C CB  . VAL B 1 322 ? -12.886 -54.600 -20.128 1.00 73.32  ? 322 VAL B CB  1 
ATOM   6153  C CG1 . VAL B 1 322 ? -11.510 -54.807 -20.748 1.00 68.81  ? 322 VAL B CG1 1 
ATOM   6154  C CG2 . VAL B 1 322 ? -13.561 -53.339 -20.665 1.00 70.09  ? 322 VAL B CG2 1 
ATOM   6155  N N   . LEU B 1 323 ? -13.226 -57.053 -18.264 1.00 64.19  ? 323 LEU B N   1 
ATOM   6156  C CA  . LEU B 1 323 ? -12.582 -58.108 -17.495 1.00 63.42  ? 323 LEU B CA  1 
ATOM   6157  C C   . LEU B 1 323 ? -13.435 -59.369 -17.558 1.00 52.00  ? 323 LEU B C   1 
ATOM   6158  O O   . LEU B 1 323 ? -14.641 -59.263 -17.695 1.00 46.33  ? 323 LEU B O   1 
ATOM   6159  C CB  . LEU B 1 323 ? -12.407 -57.643 -16.043 1.00 58.79  ? 323 LEU B CB  1 
ATOM   6160  C CG  . LEU B 1 323 ? -11.410 -56.506 -15.822 1.00 52.25  ? 323 LEU B CG  1 
ATOM   6161  C CD1 . LEU B 1 323 ? -11.095 -56.349 -14.350 1.00 49.43  ? 323 LEU B CD1 1 
ATOM   6162  C CD2 . LEU B 1 323 ? -10.123 -56.744 -16.593 1.00 52.74  ? 323 LEU B CD2 1 
ATOM   6163  N N   . ARG B 1 324 ? -12.807 -60.533 -17.364 1.00 53.86  ? 324 ARG B N   1 
ATOM   6164  C CA  . ARG B 1 324 ? -13.545 -61.770 -17.145 1.00 58.81  ? 324 ARG B CA  1 
ATOM   6165  C C   . ARG B 1 324 ? -13.303 -62.287 -15.720 1.00 55.44  ? 324 ARG B C   1 
ATOM   6166  O O   . ARG B 1 324 ? -13.765 -63.378 -15.360 1.00 49.11  ? 324 ARG B O   1 
ATOM   6167  C CB  . ARG B 1 324 ? -13.203 -62.768 -18.261 1.00 63.15  ? 324 ARG B CB  1 
ATOM   6168  C CG  . ARG B 1 324 ? -13.559 -62.249 -19.650 1.00 68.93  ? 324 ARG B CG  1 
ATOM   6169  C CD  . ARG B 1 324 ? -13.437 -63.252 -20.791 1.00 80.46  ? 324 ARG B CD  1 
ATOM   6170  N NE  . ARG B 1 324 ? -12.107 -63.848 -20.922 1.00 86.70  ? 324 ARG B NE  1 
ATOM   6171  C CZ  . ARG B 1 324 ? -11.184 -63.485 -21.810 1.00 82.63  ? 324 ARG B CZ  1 
ATOM   6172  N NH1 . ARG B 1 324 ? -11.401 -62.481 -22.641 1.00 80.71  ? 324 ARG B NH1 1 
ATOM   6173  N NH2 . ARG B 1 324 ? -10.023 -64.113 -21.846 1.00 83.59  ? 324 ARG B NH2 1 
ATOM   6174  N N   . VAL B 1 325 ? -12.629 -61.469 -14.891 1.00 46.81  ? 325 VAL B N   1 
ATOM   6175  C CA  . VAL B 1 325 ? -12.298 -61.817 -13.512 1.00 41.50  ? 325 VAL B CA  1 
ATOM   6176  C C   . VAL B 1 325 ? -12.601 -60.617 -12.603 1.00 41.54  ? 325 VAL B C   1 
ATOM   6177  O O   . VAL B 1 325 ? -12.836 -59.505 -13.081 1.00 46.16  ? 325 VAL B O   1 
ATOM   6178  C CB  . VAL B 1 325 ? -10.819 -62.221 -13.405 1.00 47.15  ? 325 VAL B CB  1 
ATOM   6179  C CG1 . VAL B 1 325 ? -10.532 -63.492 -14.206 1.00 51.25  ? 325 VAL B CG1 1 
ATOM   6180  C CG2 . VAL B 1 325 ? -9.900  -61.067 -13.837 1.00 46.64  ? 325 VAL B CG2 1 
ATOM   6181  N N   . THR B 1 326 ? -12.571 -60.826 -11.283 1.00 40.83  ? 326 THR B N   1 
ATOM   6182  C CA  . THR B 1 326 ? -12.741 -59.717 -10.367 1.00 40.30  ? 326 THR B CA  1 
ATOM   6183  C C   . THR B 1 326 ? -11.576 -58.768 -10.557 1.00 37.53  ? 326 THR B C   1 
ATOM   6184  O O   . THR B 1 326 ? -10.441 -59.204 -10.720 1.00 37.17  ? 326 THR B O   1 
ATOM   6185  C CB  . THR B 1 326 ? -12.805 -60.157 -8.905  1.00 42.14  ? 326 THR B CB  1 
ATOM   6186  O OG1 . THR B 1 326 ? -13.923 -61.033 -8.855  1.00 42.33  ? 326 THR B OG1 1 
ATOM   6187  C CG2 . THR B 1 326 ? -13.001 -59.002 -7.942  1.00 43.15  ? 326 THR B CG2 1 
ATOM   6188  N N   . ASP B 1 327 ? -11.897 -57.478 -10.596 1.00 39.40  ? 327 ASP B N   1 
ATOM   6189  C CA  . ASP B 1 327 ? -10.901 -56.419 -10.636 1.00 34.64  ? 327 ASP B CA  1 
ATOM   6190  C C   . ASP B 1 327 ? -9.908  -56.668 -9.509  1.00 33.12  ? 327 ASP B C   1 
ATOM   6191  O O   . ASP B 1 327 ? -10.319 -56.791 -8.348  1.00 37.53  ? 327 ASP B O   1 
ATOM   6192  C CB  . ASP B 1 327 ? -11.636 -55.096 -10.513 1.00 37.10  ? 327 ASP B CB  1 
ATOM   6193  C CG  . ASP B 1 327 ? -10.770 -53.854 -10.716 1.00 38.64  ? 327 ASP B CG  1 
ATOM   6194  O OD1 . ASP B 1 327 ? -9.527  -53.997 -10.667 1.00 36.61  ? 327 ASP B OD1 1 
ATOM   6195  O OD2 . ASP B 1 327 ? -11.359 -52.767 -11.014 1.00 34.36  ? 327 ASP B OD2 1 
ATOM   6196  N N   . PRO B 1 328 ? -8.590  -56.805 -9.779  1.00 34.22  ? 328 PRO B N   1 
ATOM   6197  C CA  . PRO B 1 328 ? -7.616  -57.001 -8.699  1.00 39.50  ? 328 PRO B CA  1 
ATOM   6198  C C   . PRO B 1 328 ? -7.590  -55.812 -7.724  1.00 39.15  ? 328 PRO B C   1 
ATOM   6199  O O   . PRO B 1 328 ? -7.185  -55.960 -6.571  1.00 35.98  ? 328 PRO B O   1 
ATOM   6200  C CB  . PRO B 1 328 ? -6.272  -57.200 -9.433  1.00 40.96  ? 328 PRO B CB  1 
ATOM   6201  C CG  . PRO B 1 328 ? -6.477  -56.493 -10.767 1.00 38.51  ? 328 PRO B CG  1 
ATOM   6202  C CD  . PRO B 1 328 ? -7.938  -56.759 -11.101 1.00 42.33  ? 328 PRO B CD  1 
ATOM   6203  N N   . ARG B 1 329 ? -8.068  -54.642 -8.173  1.00 35.39  ? 329 ARG B N   1 
ATOM   6204  C CA  . ARG B 1 329 ? -8.173  -53.498 -7.267  1.00 36.40  ? 329 ARG B CA  1 
ATOM   6205  C C   . ARG B 1 329 ? -9.322  -53.700 -6.276  1.00 34.15  ? 329 ARG B C   1 
ATOM   6206  O O   . ARG B 1 329 ? -9.257  -53.184 -5.149  1.00 36.03  ? 329 ARG B O   1 
ATOM   6207  C CB  . ARG B 1 329 ? -8.359  -52.183 -8.032  1.00 40.18  ? 329 ARG B CB  1 
ATOM   6208  C CG  . ARG B 1 329 ? -7.218  -51.854 -8.986  1.00 43.84  ? 329 ARG B CG  1 
ATOM   6209  C CD  . ARG B 1 329 ? -7.579  -50.671 -9.894  1.00 43.00  ? 329 ARG B CD  1 
ATOM   6210  N NE  . ARG B 1 329 ? -8.696  -50.998 -10.787 1.00 40.18  ? 329 ARG B NE  1 
ATOM   6211  C CZ  . ARG B 1 329 ? -9.267  -50.148 -11.647 1.00 41.08  ? 329 ARG B CZ  1 
ATOM   6212  N NH1 . ARG B 1 329 ? -8.738  -48.948 -11.859 1.00 37.39  ? 329 ARG B NH1 1 
ATOM   6213  N NH2 . ARG B 1 329 ? -10.340 -50.526 -12.324 1.00 38.43  ? 329 ARG B NH2 1 
ATOM   6214  N N   . TYR B 1 330 ? -10.358 -54.457 -6.681  1.00 32.42  ? 330 TYR B N   1 
ATOM   6215  C CA  . TYR B 1 330 ? -11.433 -54.811 -5.765  1.00 32.69  ? 330 TYR B CA  1 
ATOM   6216  C C   . TYR B 1 330 ? -10.927 -55.768 -4.683  1.00 32.87  ? 330 TYR B C   1 
ATOM   6217  O O   . TYR B 1 330 ? -11.187 -55.565 -3.510  1.00 32.05  ? 330 TYR B O   1 
ATOM   6218  C CB  . TYR B 1 330 ? -12.606 -55.401 -6.540  1.00 37.20  ? 330 TYR B CB  1 
ATOM   6219  C CG  . TYR B 1 330 ? -13.748 -55.830 -5.675  1.00 38.26  ? 330 TYR B CG  1 
ATOM   6220  C CD1 . TYR B 1 330 ? -13.731 -57.059 -5.035  1.00 38.24  ? 330 TYR B CD1 1 
ATOM   6221  C CD2 . TYR B 1 330 ? -14.829 -54.993 -5.470  1.00 36.99  ? 330 TYR B CD2 1 
ATOM   6222  C CE1 . TYR B 1 330 ? -14.797 -57.473 -4.250  1.00 36.70  ? 330 TYR B CE1 1 
ATOM   6223  C CE2 . TYR B 1 330 ? -15.906 -55.398 -4.696  1.00 44.94  ? 330 TYR B CE2 1 
ATOM   6224  C CZ  . TYR B 1 330 ? -15.895 -56.639 -4.076  1.00 41.76  ? 330 TYR B CZ  1 
ATOM   6225  O OH  . TYR B 1 330 ? -16.946 -57.033 -3.257  1.00 39.45  ? 330 TYR B OH  1 
ATOM   6226  N N   . VAL B 1 331 ? -10.153 -56.776 -5.096  1.00 32.79  ? 331 VAL B N   1 
ATOM   6227  C CA  . VAL B 1 331 ? -9.621  -57.812 -4.217  1.00 36.16  ? 331 VAL B CA  1 
ATOM   6228  C C   . VAL B 1 331 ? -8.758  -57.193 -3.121  1.00 36.90  ? 331 VAL B C   1 
ATOM   6229  O O   . VAL B 1 331 ? -8.879  -57.562 -1.946  1.00 36.36  ? 331 VAL B O   1 
ATOM   6230  C CB  . VAL B 1 331 ? -8.844  -58.862 -5.048  1.00 41.38  ? 331 VAL B CB  1 
ATOM   6231  C CG1 . VAL B 1 331 ? -8.081  -59.868 -4.189  1.00 42.44  ? 331 VAL B CG1 1 
ATOM   6232  C CG2 . VAL B 1 331 ? -9.784  -59.609 -5.998  1.00 42.11  ? 331 VAL B CG2 1 
ATOM   6233  N N   . ALA B 1 332 ? -7.907  -56.210 -3.471  1.00 35.99  ? 332 ALA B N   1 
ATOM   6234  C CA  . ALA B 1 332 ? -7.036  -55.619 -2.459  1.00 36.42  ? 332 ALA B CA  1 
ATOM   6235  C C   . ALA B 1 332 ? -7.831  -54.832 -1.412  1.00 37.55  ? 332 ALA B C   1 
ATOM   6236  O O   . ALA B 1 332 ? -7.457  -54.834 -0.230  1.00 38.34  ? 332 ALA B O   1 
ATOM   6237  C CB  . ALA B 1 332 ? -5.988  -54.754 -3.100  1.00 38.28  ? 332 ALA B CB  1 
ATOM   6238  N N   . GLN B 1 333 ? -8.879  -54.129 -1.869  1.00 36.20  ? 333 GLN B N   1 
ATOM   6239  C CA  . GLN B 1 333 ? -9.798  -53.391 -1.000  1.00 36.83  ? 333 GLN B CA  1 
ATOM   6240  C C   . GLN B 1 333 ? -10.566 -54.338 -0.084  1.00 34.00  ? 333 GLN B C   1 
ATOM   6241  O O   . GLN B 1 333 ? -10.777 -54.027 1.096   1.00 39.12  ? 333 GLN B O   1 
ATOM   6242  C CB  . GLN B 1 333 ? -10.785 -52.534 -1.806  1.00 34.99  ? 333 GLN B CB  1 
ATOM   6243  C CG  . GLN B 1 333 ? -10.103 -51.316 -2.447  1.00 41.21  ? 333 GLN B CG  1 
ATOM   6244  C CD  . GLN B 1 333 ? -11.033 -50.594 -3.388  1.00 47.88  ? 333 GLN B CD  1 
ATOM   6245  O OE1 . GLN B 1 333 ? -11.302 -51.015 -4.524  1.00 50.91  ? 333 GLN B OE1 1 
ATOM   6246  N NE2 . GLN B 1 333 ? -11.572 -49.506 -2.891  1.00 48.32  ? 333 GLN B NE2 1 
ATOM   6247  N N   . ARG B 1 334 ? -11.015 -55.471 -0.617  1.00 32.64  ? 334 ARG B N   1 
ATOM   6248  C CA  . ARG B 1 334 ? -11.702 -56.470 0.226   1.00 36.18  ? 334 ARG B CA  1 
ATOM   6249  C C   . ARG B 1 334 ? -10.767 -56.994 1.318   1.00 31.46  ? 334 ARG B C   1 
ATOM   6250  O O   . ARG B 1 334 ? -11.138 -57.062 2.497   1.00 33.90  ? 334 ARG B O   1 
ATOM   6251  C CB  . ARG B 1 334 ? -12.193 -57.640 -0.619  1.00 39.44  ? 334 ARG B CB  1 
ATOM   6252  C CG  . ARG B 1 334 ? -12.808 -58.783 0.173   1.00 43.01  ? 334 ARG B CG  1 
ATOM   6253  C CD  . ARG B 1 334 ? -13.400 -59.830 -0.764  1.00 40.71  ? 334 ARG B CD  1 
ATOM   6254  N NE  . ARG B 1 334 ? -13.931 -60.995 -0.040  1.00 44.41  ? 334 ARG B NE  1 
ATOM   6255  C CZ  . ARG B 1 334 ? -14.994 -61.013 0.766   1.00 45.83  ? 334 ARG B CZ  1 
ATOM   6256  N NH1 . ARG B 1 334 ? -15.806 -59.975 0.857   1.00 43.95  ? 334 ARG B NH1 1 
ATOM   6257  N NH2 . ARG B 1 334 ? -15.277 -62.109 1.451   1.00 47.57  ? 334 ARG B NH2 1 
ATOM   6258  N N   . ASP B 1 335 ? -9.539  -57.336 0.906   1.00 33.82  ? 335 ASP B N   1 
ATOM   6259  C CA  . ASP B 1 335 ? -8.503  -57.772 1.836   1.00 34.11  ? 335 ASP B CA  1 
ATOM   6260  C C   . ASP B 1 335 ? -8.280  -56.719 2.938   1.00 39.49  ? 335 ASP B C   1 
ATOM   6261  O O   . ASP B 1 335 ? -8.205  -57.069 4.121   1.00 34.28  ? 335 ASP B O   1 
ATOM   6262  C CB  . ASP B 1 335 ? -7.205  -58.127 1.119   1.00 38.26  ? 335 ASP B CB  1 
ATOM   6263  C CG  . ASP B 1 335 ? -6.135  -58.637 2.074   1.00 47.01  ? 335 ASP B CG  1 
ATOM   6264  O OD1 . ASP B 1 335 ? -6.338  -59.724 2.647   1.00 51.42  ? 335 ASP B OD1 1 
ATOM   6265  O OD2 . ASP B 1 335 ? -5.122  -57.925 2.273   1.00 48.80  ? 335 ASP B OD2 1 
ATOM   6266  N N   . PHE B 1 336 ? -8.206  -55.417 2.574   1.00 38.07  ? 336 PHE B N   1 
ATOM   6267  C CA  . PHE B 1 336 ? -8.119  -54.344 3.567   1.00 34.62  ? 336 PHE B CA  1 
ATOM   6268  C C   . PHE B 1 336 ? -9.339  -54.351 4.505   1.00 33.09  ? 336 PHE B C   1 
ATOM   6269  O O   . PHE B 1 336 ? -9.194  -54.291 5.732   1.00 34.88  ? 336 PHE B O   1 
ATOM   6270  C CB  . PHE B 1 336 ? -7.938  -52.984 2.870   1.00 35.57  ? 336 PHE B CB  1 
ATOM   6271  C CG  . PHE B 1 336 ? -7.770  -51.820 3.810   1.00 35.31  ? 336 PHE B CG  1 
ATOM   6272  C CD1 . PHE B 1 336 ? -8.875  -51.251 4.440   1.00 40.18  ? 336 PHE B CD1 1 
ATOM   6273  C CD2 . PHE B 1 336 ? -6.504  -51.339 4.117   1.00 40.37  ? 336 PHE B CD2 1 
ATOM   6274  C CE1 . PHE B 1 336 ? -8.709  -50.206 5.342   1.00 39.99  ? 336 PHE B CE1 1 
ATOM   6275  C CE2 . PHE B 1 336 ? -6.335  -50.305 5.029   1.00 39.61  ? 336 PHE B CE2 1 
ATOM   6276  C CZ  . PHE B 1 336 ? -7.441  -49.737 5.626   1.00 41.61  ? 336 PHE B CZ  1 
ATOM   6277  N N   . ALA B 1 337 ? -10.557 -54.400 3.950   1.00 33.09  ? 337 ALA B N   1 
ATOM   6278  C CA  . ALA B 1 337 ? -11.769 -54.374 4.760   1.00 35.14  ? 337 ALA B CA  1 
ATOM   6279  C C   . ALA B 1 337 ? -11.831 -55.582 5.718   1.00 44.42  ? 337 ALA B C   1 
ATOM   6280  O O   . ALA B 1 337 ? -12.174 -55.446 6.899   1.00 41.08  ? 337 ALA B O   1 
ATOM   6281  C CB  . ALA B 1 337 ? -12.958 -54.322 3.841   1.00 35.40  ? 337 ALA B CB  1 
ATOM   6282  N N   . LEU B 1 338 ? -11.514 -56.788 5.221   1.00 41.38  ? 338 LEU B N   1 
ATOM   6283  C CA  . LEU B 1 338 ? -11.571 -57.980 6.067   1.00 43.48  ? 338 LEU B CA  1 
ATOM   6284  C C   . LEU B 1 338 ? -10.634 -57.820 7.263   1.00 45.42  ? 338 LEU B C   1 
ATOM   6285  O O   . LEU B 1 338 ? -10.981 -58.210 8.359   1.00 45.71  ? 338 LEU B O   1 
ATOM   6286  C CB  . LEU B 1 338 ? -11.198 -59.226 5.252   1.00 43.71  ? 338 LEU B CB  1 
ATOM   6287  C CG  . LEU B 1 338 ? -12.217 -59.657 4.186   1.00 44.78  ? 338 LEU B CG  1 
ATOM   6288  C CD1 . LEU B 1 338 ? -11.649 -60.753 3.303   1.00 44.66  ? 338 LEU B CD1 1 
ATOM   6289  C CD2 . LEU B 1 338 ? -13.533 -60.113 4.817   1.00 47.61  ? 338 LEU B CD2 1 
ATOM   6290  N N   . LYS B 1 339 ? -9.455  -57.233 7.041   1.00 45.64  ? 339 LYS B N   1 
ATOM   6291  C CA  . LYS B 1 339 ? -8.453  -57.068 8.074   1.00 52.07  ? 339 LYS B CA  1 
ATOM   6292  C C   . LYS B 1 339 ? -8.881  -55.980 9.070   1.00 53.21  ? 339 LYS B C   1 
ATOM   6293  O O   . LYS B 1 339 ? -8.699  -56.139 10.271  1.00 52.39  ? 339 LYS B O   1 
ATOM   6294  C CB  . LYS B 1 339 ? -7.119  -56.746 7.387   1.00 65.34  ? 339 LYS B CB  1 
ATOM   6295  C CG  . LYS B 1 339 ? -5.897  -57.510 7.894   1.00 82.42  ? 339 LYS B CG  1 
ATOM   6296  C CD  . LYS B 1 339 ? -4.581  -57.134 7.196   1.00 90.67  ? 339 LYS B CD  1 
ATOM   6297  C CE  . LYS B 1 339 ? -4.541  -57.461 5.714   1.00 93.73  ? 339 LYS B CE  1 
ATOM   6298  N NZ  . LYS B 1 339 ? -3.241  -57.090 5.095   1.00 95.19  ? 339 LYS B NZ  1 
ATOM   6299  N N   . HIS B 1 340 ? -9.442  -54.863 8.582   1.00 45.11  ? 340 HIS B N   1 
ATOM   6300  C CA  . HIS B 1 340 ? -9.487  -53.633 9.356   1.00 42.18  ? 340 HIS B CA  1 
ATOM   6301  C C   . HIS B 1 340 ? -10.897 -53.225 9.759   1.00 40.02  ? 340 HIS B C   1 
ATOM   6302  O O   . HIS B 1 340 ? -11.017 -52.569 10.782  1.00 41.53  ? 340 HIS B O   1 
ATOM   6303  C CB  . HIS B 1 340 ? -8.804  -52.474 8.621   1.00 47.35  ? 340 HIS B CB  1 
ATOM   6304  C CG  . HIS B 1 340 ? -7.341  -52.645 8.400   1.00 46.71  ? 340 HIS B CG  1 
ATOM   6305  N ND1 . HIS B 1 340 ? -6.419  -52.571 9.421   1.00 53.33  ? 340 HIS B ND1 1 
ATOM   6306  C CD2 . HIS B 1 340 ? -6.635  -52.865 7.272   1.00 43.69  ? 340 HIS B CD2 1 
ATOM   6307  C CE1 . HIS B 1 340 ? -5.205  -52.758 8.917   1.00 52.53  ? 340 HIS B CE1 1 
ATOM   6308  N NE2 . HIS B 1 340 ? -5.313  -52.903 7.607   1.00 44.31  ? 340 HIS B NE2 1 
ATOM   6309  N N   . LEU B 1 341 ? -11.957 -53.564 9.004   1.00 38.10  ? 341 LEU B N   1 
ATOM   6310  C CA  . LEU B 1 341 ? -13.308 -53.230 9.465   1.00 39.47  ? 341 LEU B CA  1 
ATOM   6311  C C   . LEU B 1 341 ? -14.346 -54.293 9.101   1.00 40.24  ? 341 LEU B C   1 
ATOM   6312  O O   . LEU B 1 341 ? -15.409 -53.966 8.562   1.00 38.90  ? 341 LEU B O   1 
ATOM   6313  C CB  . LEU B 1 341 ? -13.709 -51.879 8.876   1.00 37.72  ? 341 LEU B CB  1 
ATOM   6314  C CG  . LEU B 1 341 ? -13.601 -51.816 7.357   1.00 37.83  ? 341 LEU B CG  1 
ATOM   6315  C CD1 . LEU B 1 341 ? -14.877 -51.260 6.706   1.00 36.32  ? 341 LEU B CD1 1 
ATOM   6316  C CD2 . LEU B 1 341 ? -12.351 -51.045 6.946   1.00 39.67  ? 341 LEU B CD2 1 
ATOM   6317  N N   . PRO B 1 342 ? -14.105 -55.585 9.440   1.00 45.10  ? 342 PRO B N   1 
ATOM   6318  C CA  . PRO B 1 342 ? -15.039 -56.677 9.125   1.00 45.62  ? 342 PRO B CA  1 
ATOM   6319  C C   . PRO B 1 342 ? -16.466 -56.587 9.690   1.00 45.08  ? 342 PRO B C   1 
ATOM   6320  O O   . PRO B 1 342 ? -17.392 -57.149 9.109   1.00 42.49  ? 342 PRO B O   1 
ATOM   6321  C CB  . PRO B 1 342 ? -14.316 -57.917 9.712   1.00 50.52  ? 342 PRO B CB  1 
ATOM   6322  C CG  . PRO B 1 342 ? -13.430 -57.346 10.800  1.00 50.00  ? 342 PRO B CG  1 
ATOM   6323  C CD  . PRO B 1 342 ? -12.905 -56.078 10.146  1.00 48.09  ? 342 PRO B CD  1 
ATOM   6324  N N   . ASP B 1 343 ? -16.674 -55.867 10.799  1.00 44.81  ? 343 ASP B N   1 
ATOM   6325  C CA  . ASP B 1 343 ? -18.001 -55.811 11.419  1.00 49.43  ? 343 ASP B CA  1 
ATOM   6326  C C   . ASP B 1 343 ? -18.789 -54.572 10.953  1.00 51.21  ? 343 ASP B C   1 
ATOM   6327  O O   . ASP B 1 343 ? -19.990 -54.447 11.210  1.00 47.80  ? 343 ASP B O   1 
ATOM   6328  C CB  . ASP B 1 343 ? -17.880 -55.910 12.947  1.00 55.55  ? 343 ASP B CB  1 
ATOM   6329  C CG  . ASP B 1 343 ? -17.176 -57.182 13.408  1.00 62.05  ? 343 ASP B CG  1 
ATOM   6330  O OD1 . ASP B 1 343 ? -17.594 -58.276 12.965  1.00 60.87  ? 343 ASP B OD1 1 
ATOM   6331  O OD2 . ASP B 1 343 ? -16.219 -57.078 14.205  1.00 68.05  ? 343 ASP B OD2 1 
ATOM   6332  N N   . ASP B 1 344 ? -18.147 -53.672 10.200  1.00 47.88  ? 344 ASP B N   1 
ATOM   6333  C CA  . ASP B 1 344 ? -18.852 -52.506 9.668   1.00 47.02  ? 344 ASP B CA  1 
ATOM   6334  C C   . ASP B 1 344 ? -20.036 -52.959 8.808   1.00 42.51  ? 344 ASP B C   1 
ATOM   6335  O O   . ASP B 1 344 ? -19.870 -53.731 7.863   1.00 41.50  ? 344 ASP B O   1 
ATOM   6336  C CB  . ASP B 1 344 ? -17.891 -51.587 8.903   1.00 44.41  ? 344 ASP B CB  1 
ATOM   6337  C CG  . ASP B 1 344 ? -18.568 -50.370 8.291   1.00 51.26  ? 344 ASP B CG  1 
ATOM   6338  O OD1 . ASP B 1 344 ? -19.289 -50.590 7.281   1.00 48.23  ? 344 ASP B OD1 1 
ATOM   6339  O OD2 . ASP B 1 344 ? -18.385 -49.205 8.834   1.00 50.00  ? 344 ASP B OD2 1 
ATOM   6340  N N   . GLU B 1 345 ? -21.216 -52.398 9.089   1.00 42.18  ? 345 GLU B N   1 
ATOM   6341  C CA  . GLU B 1 345 ? -22.462 -52.884 8.524   1.00 45.15  ? 345 GLU B CA  1 
ATOM   6342  C C   . GLU B 1 345 ? -22.544 -52.684 7.010   1.00 44.73  ? 345 GLU B C   1 
ATOM   6343  O O   . GLU B 1 345 ? -23.014 -53.591 6.324   1.00 46.00  ? 345 GLU B O   1 
ATOM   6344  C CB  . GLU B 1 345 ? -23.655 -52.279 9.256   1.00 55.98  ? 345 GLU B CB  1 
ATOM   6345  C CG  . GLU B 1 345 ? -23.939 -52.990 10.589  1.00 64.24  ? 345 GLU B CG  1 
ATOM   6346  C CD  . GLU B 1 345 ? -25.325 -52.738 11.173  1.00 70.95  ? 345 GLU B CD  1 
ATOM   6347  O OE1 . GLU B 1 345 ? -26.302 -53.434 10.776  1.00 71.80  ? 345 GLU B OE1 1 
ATOM   6348  O OE2 . GLU B 1 345 ? -25.440 -51.810 11.988  1.00 85.86  ? 345 GLU B OE2 1 
ATOM   6349  N N   . LEU B 1 346 ? -22.060 -51.555 6.469   1.00 35.63  ? 346 LEU B N   1 
ATOM   6350  C CA  . LEU B 1 346 ? -22.131 -51.334 5.024   1.00 38.21  ? 346 LEU B CA  1 
ATOM   6351  C C   . LEU B 1 346 ? -21.162 -52.285 4.325   1.00 30.93  ? 346 LEU B C   1 
ATOM   6352  O O   . LEU B 1 346 ? -21.495 -52.847 3.295   1.00 40.75  ? 346 LEU B O   1 
ATOM   6353  C CB  . LEU B 1 346 ? -21.868 -49.859 4.688   1.00 39.22  ? 346 LEU B CB  1 
ATOM   6354  C CG  . LEU B 1 346 ? -22.855 -48.837 5.278   1.00 45.15  ? 346 LEU B CG  1 
ATOM   6355  C CD1 . LEU B 1 346 ? -22.631 -47.451 4.685   1.00 48.03  ? 346 LEU B CD1 1 
ATOM   6356  C CD2 . LEU B 1 346 ? -24.316 -49.241 5.068   1.00 41.83  ? 346 LEU B CD2 1 
ATOM   6357  N N   . PHE B 1 347 ? -19.982 -52.520 4.917   1.00 35.16  ? 347 PHE B N   1 
ATOM   6358  C CA  . PHE B 1 347 ? -19.052 -53.505 4.392   1.00 39.00  ? 347 PHE B CA  1 
ATOM   6359  C C   . PHE B 1 347 ? -19.683 -54.903 4.314   1.00 41.60  ? 347 PHE B C   1 
ATOM   6360  O O   . PHE B 1 347 ? -19.388 -55.655 3.359   1.00 37.40  ? 347 PHE B O   1 
ATOM   6361  C CB  . PHE B 1 347 ? -17.742 -53.584 5.189   1.00 40.25  ? 347 PHE B CB  1 
ATOM   6362  C CG  . PHE B 1 347 ? -16.869 -54.745 4.762   1.00 41.97  ? 347 PHE B CG  1 
ATOM   6363  C CD1 . PHE B 1 347 ? -16.405 -54.836 3.448   1.00 43.27  ? 347 PHE B CD1 1 
ATOM   6364  C CD2 . PHE B 1 347 ? -16.587 -55.790 5.635   1.00 39.78  ? 347 PHE B CD2 1 
ATOM   6365  C CE1 . PHE B 1 347 ? -15.637 -55.918 3.035   1.00 43.96  ? 347 PHE B CE1 1 
ATOM   6366  C CE2 . PHE B 1 347 ? -15.842 -56.884 5.217   1.00 39.15  ? 347 PHE B CE2 1 
ATOM   6367  C CZ  . PHE B 1 347 ? -15.348 -56.938 3.927   1.00 45.99  ? 347 PHE B CZ  1 
ATOM   6368  N N   . LYS B 1 348 ? -20.474 -55.267 5.344   1.00 40.14  ? 348 LYS B N   1 
ATOM   6369  C CA  . LYS B 1 348 ? -21.155 -56.558 5.361   1.00 44.30  ? 348 LYS B CA  1 
ATOM   6370  C C   . LYS B 1 348 ? -22.065 -56.654 4.142   1.00 37.51  ? 348 LYS B C   1 
ATOM   6371  O O   . LYS B 1 348 ? -22.149 -57.715 3.540   1.00 39.48  ? 348 LYS B O   1 
ATOM   6372  C CB  . LYS B 1 348 ? -21.921 -56.825 6.662   1.00 52.20  ? 348 LYS B CB  1 
ATOM   6373  C CG  . LYS B 1 348 ? -21.033 -56.930 7.896   1.00 57.10  ? 348 LYS B CG  1 
ATOM   6374  C CD  . LYS B 1 348 ? -21.708 -57.471 9.131   1.00 67.35  ? 348 LYS B CD  1 
ATOM   6375  C CE  . LYS B 1 348 ? -20.715 -58.114 10.079  1.00 75.46  ? 348 LYS B CE  1 
ATOM   6376  N NZ  . LYS B 1 348 ? -21.211 -58.128 11.477  1.00 86.69  ? 348 LYS B NZ  1 
ATOM   6377  N N   . ILE B 1 349 ? -22.678 -55.544 3.715   1.00 38.89  ? 349 ILE B N   1 
ATOM   6378  C CA  . ILE B 1 349 ? -23.528 -55.615 2.529   1.00 41.07  ? 349 ILE B CA  1 
ATOM   6379  C C   . ILE B 1 349 ? -22.658 -55.816 1.274   1.00 38.21  ? 349 ILE B C   1 
ATOM   6380  O O   . ILE B 1 349 ? -23.021 -56.592 0.396   1.00 39.43  ? 349 ILE B O   1 
ATOM   6381  C CB  . ILE B 1 349 ? -24.456 -54.378 2.433   1.00 41.13  ? 349 ILE B CB  1 
ATOM   6382  C CG1 . ILE B 1 349 ? -25.302 -54.190 3.697   1.00 39.92  ? 349 ILE B CG1 1 
ATOM   6383  C CG2 . ILE B 1 349 ? -25.306 -54.432 1.172   1.00 38.53  ? 349 ILE B CG2 1 
ATOM   6384  C CD1 . ILE B 1 349 ? -26.401 -53.158 3.567   1.00 42.95  ? 349 ILE B CD1 1 
ATOM   6385  N N   . VAL B 1 350 ? -21.544 -55.059 1.164   1.00 39.74  ? 350 VAL B N   1 
ATOM   6386  C CA  . VAL B 1 350 ? -20.622 -55.149 0.036   1.00 37.85  ? 350 VAL B CA  1 
ATOM   6387  C C   . VAL B 1 350 ? -20.089 -56.593 -0.031  1.00 39.85  ? 350 VAL B C   1 
ATOM   6388  O O   . VAL B 1 350 ? -19.950 -57.179 -1.089  1.00 35.87  ? 350 VAL B O   1 
ATOM   6389  C CB  . VAL B 1 350 ? -19.515 -54.067 0.135   1.00 41.08  ? 350 VAL B CB  1 
ATOM   6390  C CG1 . VAL B 1 350 ? -18.287 -54.326 -0.724  1.00 43.23  ? 350 VAL B CG1 1 
ATOM   6391  C CG2 . VAL B 1 350 ? -20.036 -52.680 -0.222  1.00 40.61  ? 350 VAL B CG2 1 
ATOM   6392  N N   . SER B 1 351 ? -19.832 -57.193 1.133   1.00 38.56  ? 351 SER B N   1 
ATOM   6393  C CA  . SER B 1 351 ? -19.288 -58.539 1.210   1.00 39.98  ? 351 SER B CA  1 
ATOM   6394  C C   . SER B 1 351 ? -20.314 -59.553 0.712   1.00 38.77  ? 351 SER B C   1 
ATOM   6395  O O   . SER B 1 351 ? -19.982 -60.402 -0.107  1.00 39.76  ? 351 SER B O   1 
ATOM   6396  C CB  . SER B 1 351 ? -18.804 -58.858 2.608   1.00 37.56  ? 351 SER B CB  1 
ATOM   6397  O OG  . SER B 1 351 ? -17.953 -59.984 2.564   1.00 42.21  ? 351 SER B OG  1 
ATOM   6398  N N   . LEU B 1 352 ? -21.562 -59.414 1.171   1.00 39.89  ? 352 LEU B N   1 
ATOM   6399  C CA  . LEU B 1 352 ? -22.644 -60.277 0.738   1.00 39.85  ? 352 LEU B CA  1 
ATOM   6400  C C   . LEU B 1 352 ? -22.878 -60.137 -0.767  1.00 38.61  ? 352 LEU B C   1 
ATOM   6401  O O   . LEU B 1 352 ? -23.144 -61.127 -1.428  1.00 37.89  ? 352 LEU B O   1 
ATOM   6402  C CB  . LEU B 1 352 ? -23.902 -59.914 1.525   1.00 44.00  ? 352 LEU B CB  1 
ATOM   6403  C CG  . LEU B 1 352 ? -25.116 -60.817 1.304   1.00 47.19  ? 352 LEU B CG  1 
ATOM   6404  C CD1 . LEU B 1 352 ? -24.917 -62.173 1.966   1.00 47.09  ? 352 LEU B CD1 1 
ATOM   6405  C CD2 . LEU B 1 352 ? -26.386 -60.157 1.826   1.00 49.18  ? 352 LEU B CD2 1 
ATOM   6406  N N   . CYS B 1 353 ? -22.753 -58.927 -1.316  1.00 37.46  ? 353 CYS B N   1 
ATOM   6407  C CA  . CYS B 1 353 ? -22.903 -58.728 -2.754  1.00 43.29  ? 353 CYS B CA  1 
ATOM   6408  C C   . CYS B 1 353 ? -21.833 -59.503 -3.530  1.00 44.65  ? 353 CYS B C   1 
ATOM   6409  O O   . CYS B 1 353 ? -22.124 -60.017 -4.609  1.00 41.70  ? 353 CYS B O   1 
ATOM   6410  C CB  . CYS B 1 353 ? -22.849 -57.253 -3.155  1.00 41.32  ? 353 CYS B CB  1 
ATOM   6411  S SG  . CYS B 1 353 ? -24.337 -56.336 -2.665  1.00 44.39  ? 353 CYS B SG  1 
ATOM   6412  N N   . TYR B 1 354 ? -20.612 -59.592 -2.980  1.00 39.20  ? 354 TYR B N   1 
ATOM   6413  C CA  . TYR B 1 354 ? -19.521 -60.294 -3.640  1.00 40.19  ? 354 TYR B CA  1 
ATOM   6414  C C   . TYR B 1 354 ? -19.834 -61.788 -3.802  1.00 44.54  ? 354 TYR B C   1 
ATOM   6415  O O   . TYR B 1 354 ? -19.459 -62.388 -4.805  1.00 42.82  ? 354 TYR B O   1 
ATOM   6416  C CB  . TYR B 1 354 ? -18.229 -60.174 -2.843  1.00 44.01  ? 354 TYR B CB  1 
ATOM   6417  C CG  . TYR B 1 354 ? -17.004 -60.629 -3.588  1.00 44.75  ? 354 TYR B CG  1 
ATOM   6418  C CD1 . TYR B 1 354 ? -16.879 -60.357 -4.942  1.00 42.84  ? 354 TYR B CD1 1 
ATOM   6419  C CD2 . TYR B 1 354 ? -15.967 -61.286 -2.948  1.00 46.80  ? 354 TYR B CD2 1 
ATOM   6420  C CE1 . TYR B 1 354 ? -15.768 -60.757 -5.648  1.00 42.72  ? 354 TYR B CE1 1 
ATOM   6421  C CE2 . TYR B 1 354 ? -14.836 -61.690 -3.646  1.00 48.17  ? 354 TYR B CE2 1 
ATOM   6422  C CZ  . TYR B 1 354 ? -14.736 -61.405 -5.001  1.00 48.22  ? 354 TYR B CZ  1 
ATOM   6423  O OH  . TYR B 1 354 ? -13.664 -61.739 -5.795  1.00 48.85  ? 354 TYR B OH  1 
ATOM   6424  N N   . GLU B 1 355 ? -20.509 -62.366 -2.802  1.00 45.73  ? 355 GLU B N   1 
ATOM   6425  C CA  . GLU B 1 355 ? -21.061 -63.714 -2.882  1.00 49.44  ? 355 GLU B CA  1 
ATOM   6426  C C   . GLU B 1 355 ? -22.260 -63.793 -3.843  1.00 47.81  ? 355 GLU B C   1 
ATOM   6427  O O   . GLU B 1 355 ? -22.293 -64.632 -4.744  1.00 52.03  ? 355 GLU B O   1 
ATOM   6428  C CB  . GLU B 1 355 ? -21.473 -64.170 -1.477  1.00 48.25  ? 355 GLU B CB  1 
ATOM   6429  C CG  . GLU B 1 355 ? -22.371 -65.391 -1.490  1.00 56.14  ? 355 GLU B CG  1 
ATOM   6430  C CD  . GLU B 1 355 ? -22.647 -65.971 -0.113  1.00 64.22  ? 355 GLU B CD  1 
ATOM   6431  O OE1 . GLU B 1 355 ? -23.047 -67.160 -0.056  1.00 71.48  ? 355 GLU B OE1 1 
ATOM   6432  O OE2 . GLU B 1 355 ? -22.487 -65.230 0.894   1.00 60.22  ? 355 GLU B OE2 1 
ATOM   6433  N N   . VAL B 1 356 ? -23.250 -62.919 -3.658  1.00 44.42  ? 356 VAL B N   1 
ATOM   6434  C CA  . VAL B 1 356 ? -24.578 -63.117 -4.233  1.00 47.74  ? 356 VAL B CA  1 
ATOM   6435  C C   . VAL B 1 356 ? -24.671 -62.583 -5.666  1.00 46.85  ? 356 VAL B C   1 
ATOM   6436  O O   . VAL B 1 356 ? -25.253 -63.240 -6.528  1.00 43.60  ? 356 VAL B O   1 
ATOM   6437  C CB  . VAL B 1 356 ? -25.639 -62.481 -3.320  1.00 45.74  ? 356 VAL B CB  1 
ATOM   6438  C CG1 . VAL B 1 356 ? -27.010 -62.386 -3.975  1.00 48.26  ? 356 VAL B CG1 1 
ATOM   6439  C CG2 . VAL B 1 356 ? -25.707 -63.217 -1.996  1.00 48.90  ? 356 VAL B CG2 1 
ATOM   6440  N N   . ILE B 1 357 ? -24.123 -61.387 -5.927  1.00 42.02  ? 357 ILE B N   1 
ATOM   6441  C CA  . ILE B 1 357 ? -24.430 -60.697 -7.173  1.00 41.37  ? 357 ILE B CA  1 
ATOM   6442  C C   . ILE B 1 357 ? -23.795 -61.446 -8.344  1.00 42.67  ? 357 ILE B C   1 
ATOM   6443  O O   . ILE B 1 357 ? -24.408 -61.542 -9.407  1.00 42.57  ? 357 ILE B O   1 
ATOM   6444  C CB  . ILE B 1 357 ? -24.023 -59.213 -7.147  1.00 41.76  ? 357 ILE B CB  1 
ATOM   6445  C CG1 . ILE B 1 357 ? -24.750 -58.429 -6.050  1.00 40.18  ? 357 ILE B CG1 1 
ATOM   6446  C CG2 . ILE B 1 357 ? -24.225 -58.592 -8.523  1.00 45.54  ? 357 ILE B CG2 1 
ATOM   6447  C CD1 . ILE B 1 357 ? -26.235 -58.371 -6.210  1.00 44.02  ? 357 ILE B CD1 1 
ATOM   6448  N N   . PRO B 1 358 ? -22.561 -61.987 -8.220  1.00 44.02  ? 358 PRO B N   1 
ATOM   6449  C CA  . PRO B 1 358 ? -21.976 -62.783 -9.305  1.00 45.88  ? 358 PRO B CA  1 
ATOM   6450  C C   . PRO B 1 358 ? -22.732 -64.072 -9.617  1.00 49.07  ? 358 PRO B C   1 
ATOM   6451  O O   . PRO B 1 358 ? -22.744 -64.486 -10.778 1.00 41.33  ? 358 PRO B O   1 
ATOM   6452  C CB  . PRO B 1 358 ? -20.577 -63.121 -8.793  1.00 45.29  ? 358 PRO B CB  1 
ATOM   6453  C CG  . PRO B 1 358 ? -20.296 -61.989 -7.824  1.00 50.07  ? 358 PRO B CG  1 
ATOM   6454  C CD  . PRO B 1 358 ? -21.619 -61.798 -7.104  1.00 44.32  ? 358 PRO B CD  1 
ATOM   6455  N N   . GLU B 1 359 ? -23.341 -64.691 -8.588  1.00 49.15  ? 359 GLU B N   1 
ATOM   6456  C CA  . GLU B 1 359 ? -24.143 -65.891 -8.796  1.00 57.38  ? 359 GLU B CA  1 
ATOM   6457  C C   . GLU B 1 359 ? -25.398 -65.531 -9.592  1.00 51.13  ? 359 GLU B C   1 
ATOM   6458  O O   . GLU B 1 359 ? -25.757 -66.237 -10.531 1.00 52.29  ? 359 GLU B O   1 
ATOM   6459  C CB  . GLU B 1 359 ? -24.497 -66.591 -7.476  1.00 64.86  ? 359 GLU B CB  1 
ATOM   6460  C CG  . GLU B 1 359 ? -23.416 -67.548 -6.977  1.00 78.40  ? 359 GLU B CG  1 
ATOM   6461  C CD  . GLU B 1 359 ? -23.168 -68.822 -7.788  1.00 90.49  ? 359 GLU B CD  1 
ATOM   6462  O OE1 . GLU B 1 359 ? -22.365 -69.671 -7.326  1.00 95.51  ? 359 GLU B OE1 1 
ATOM   6463  O OE2 . GLU B 1 359 ? -23.767 -68.981 -8.878  1.00 93.41  ? 359 GLU B OE2 1 
ATOM   6464  N N   . VAL B 1 360 ? -26.030 -64.403 -9.239  1.00 51.22  ? 360 VAL B N   1 
ATOM   6465  C CA  . VAL B 1 360 ? -27.239 -63.958 -9.913  1.00 52.14  ? 360 VAL B CA  1 
ATOM   6466  C C   . VAL B 1 360 ? -26.930 -63.555 -11.361 1.00 60.20  ? 360 VAL B C   1 
ATOM   6467  O O   . VAL B 1 360 ? -27.765 -63.753 -12.241 1.00 54.38  ? 360 VAL B O   1 
ATOM   6468  C CB  . VAL B 1 360 ? -27.928 -62.825 -9.131  1.00 50.48  ? 360 VAL B CB  1 
ATOM   6469  C CG1 . VAL B 1 360 ? -29.133 -62.249 -9.877  1.00 46.40  ? 360 VAL B CG1 1 
ATOM   6470  C CG2 . VAL B 1 360 ? -28.332 -63.287 -7.733  1.00 50.90  ? 360 VAL B CG2 1 
ATOM   6471  N N   . LEU B 1 361 ? -25.745 -62.981 -11.608 1.00 55.45  ? 361 LEU B N   1 
ATOM   6472  C CA  . LEU B 1 361 ? -25.413 -62.471 -12.928 1.00 58.30  ? 361 LEU B CA  1 
ATOM   6473  C C   . LEU B 1 361 ? -25.105 -63.647 -13.857 1.00 53.37  ? 361 LEU B C   1 
ATOM   6474  O O   . LEU B 1 361 ? -25.476 -63.613 -15.016 1.00 49.86  ? 361 LEU B O   1 
ATOM   6475  C CB  . LEU B 1 361 ? -24.232 -61.489 -12.834 1.00 54.63  ? 361 LEU B CB  1 
ATOM   6476  C CG  . LEU B 1 361 ? -24.588 -60.060 -12.406 1.00 55.74  ? 361 LEU B CG  1 
ATOM   6477  C CD1 . LEU B 1 361 ? -23.334 -59.232 -12.174 1.00 51.10  ? 361 LEU B CD1 1 
ATOM   6478  C CD2 . LEU B 1 361 ? -25.482 -59.393 -13.449 1.00 55.63  ? 361 LEU B CD2 1 
ATOM   6479  N N   . LYS B 1 362 ? -24.446 -64.692 -13.349 1.00 53.18  ? 362 LYS B N   1 
ATOM   6480  C CA  . LYS B 1 362 ? -24.201 -65.894 -14.141 1.00 59.03  ? 362 LYS B CA  1 
ATOM   6481  C C   . LYS B 1 362 ? -25.531 -66.500 -14.594 1.00 58.00  ? 362 LYS B C   1 
ATOM   6482  O O   . LYS B 1 362 ? -25.717 -66.839 -15.768 1.00 52.66  ? 362 LYS B O   1 
ATOM   6483  C CB  . LYS B 1 362 ? -23.379 -66.914 -13.347 1.00 61.06  ? 362 LYS B CB  1 
ATOM   6484  C CG  . LYS B 1 362 ? -21.920 -66.527 -13.133 1.00 64.00  ? 362 LYS B CG  1 
ATOM   6485  C CD  . LYS B 1 362 ? -21.141 -67.535 -12.305 1.00 74.52  ? 362 LYS B CD  1 
ATOM   6486  C CE  . LYS B 1 362 ? -19.643 -67.320 -12.399 1.00 81.12  ? 362 LYS B CE  1 
ATOM   6487  N NZ  . LYS B 1 362 ? -18.899 -68.332 -11.617 1.00 79.29  ? 362 LYS B NZ  1 
ATOM   6488  N N   . LYS B 1 363 ? -26.473 -66.569 -13.655 1.00 54.74  ? 363 LYS B N   1 
ATOM   6489  C CA  . LYS B 1 363 ? -27.766 -67.174 -13.897 1.00 55.18  ? 363 LYS B CA  1 
ATOM   6490  C C   . LYS B 1 363 ? -28.590 -66.317 -14.860 1.00 57.36  ? 363 LYS B C   1 
ATOM   6491  O O   . LYS B 1 363 ? -29.442 -66.844 -15.558 1.00 55.66  ? 363 LYS B O   1 
ATOM   6492  C CB  . LYS B 1 363 ? -28.453 -67.401 -12.547 1.00 56.68  ? 363 LYS B CB  1 
ATOM   6493  C CG  . LYS B 1 363 ? -27.769 -68.450 -11.674 1.00 60.48  ? 363 LYS B CG  1 
ATOM   6494  C CD  . LYS B 1 363 ? -28.220 -68.443 -10.229 1.00 57.92  ? 363 LYS B CD  1 
ATOM   6495  C CE  . LYS B 1 363 ? -27.625 -69.593 -9.443  1.00 60.35  ? 363 LYS B CE  1 
ATOM   6496  N NZ  . LYS B 1 363 ? -28.342 -69.778 -8.157  1.00 63.76  ? 363 LYS B NZ  1 
ATOM   6497  N N   . HIS B 1 364 ? -28.340 -65.005 -14.911 1.00 55.42  ? 364 HIS B N   1 
ATOM   6498  C CA  . HIS B 1 364 ? -29.199 -64.118 -15.675 1.00 53.42  ? 364 HIS B CA  1 
ATOM   6499  C C   . HIS B 1 364 ? -28.777 -64.108 -17.142 1.00 56.84  ? 364 HIS B C   1 
ATOM   6500  O O   . HIS B 1 364 ? -29.622 -63.877 -18.002 1.00 56.40  ? 364 HIS B O   1 
ATOM   6501  C CB  . HIS B 1 364 ? -29.302 -62.738 -15.024 1.00 51.91  ? 364 HIS B CB  1 
ATOM   6502  C CG  . HIS B 1 364 ? -30.114 -61.766 -15.808 1.00 54.83  ? 364 HIS B CG  1 
ATOM   6503  N ND1 . HIS B 1 364 ? -31.439 -61.501 -15.520 1.00 61.92  ? 364 HIS B ND1 1 
ATOM   6504  C CD2 . HIS B 1 364 ? -29.803 -61.033 -16.896 1.00 52.22  ? 364 HIS B CD2 1 
ATOM   6505  C CE1 . HIS B 1 364 ? -31.894 -60.608 -16.387 1.00 61.68  ? 364 HIS B CE1 1 
ATOM   6506  N NE2 . HIS B 1 364 ? -30.913 -60.305 -17.226 1.00 59.29  ? 364 HIS B NE2 1 
ATOM   6507  N N   . GLY B 1 365 ? -27.485 -64.307 -17.427 1.00 64.06  ? 365 GLY B N   1 
ATOM   6508  C CA  . GLY B 1 365 ? -27.083 -64.815 -18.735 1.00 84.85  ? 365 GLY B CA  1 
ATOM   6509  C C   . GLY B 1 365 ? -26.529 -63.778 -19.720 1.00 100.02 ? 365 GLY B C   1 
ATOM   6510  O O   . GLY B 1 365 ? -26.067 -64.161 -20.802 1.00 89.77  ? 365 GLY B O   1 
ATOM   6511  N N   . LYS B 1 366 ? -26.586 -62.483 -19.354 1.00 119.31 ? 366 LYS B N   1 
ATOM   6512  C CA  . LYS B 1 366 ? -26.186 -61.382 -20.231 1.00 120.82 ? 366 LYS B CA  1 
ATOM   6513  C C   . LYS B 1 366 ? -24.673 -61.154 -20.161 1.00 122.42 ? 366 LYS B C   1 
ATOM   6514  O O   . LYS B 1 366 ? -24.006 -61.087 -21.193 1.00 122.52 ? 366 LYS B O   1 
ATOM   6515  C CB  . LYS B 1 366 ? -26.886 -60.062 -19.860 1.00 108.68 ? 366 LYS B CB  1 
ATOM   6516  C CG  . LYS B 1 366 ? -28.355 -59.903 -20.250 1.00 101.50 ? 366 LYS B CG  1 
ATOM   6517  C CD  . LYS B 1 366 ? -28.616 -59.789 -21.750 1.00 92.84  ? 366 LYS B CD  1 
ATOM   6518  C CE  . LYS B 1 366 ? -28.837 -61.133 -22.420 1.00 77.09  ? 366 LYS B CE  1 
ATOM   6519  N NZ  . LYS B 1 366 ? -28.309 -61.169 -23.802 1.00 58.97  ? 366 LYS B NZ  1 
ATOM   6520  N N   . ALA B 1 367 ? -24.151 -61.022 -18.933 1.00 117.14 ? 367 ALA B N   1 
ATOM   6521  C CA  . ALA B 1 367 ? -22.815 -60.498 -18.690 1.00 113.06 ? 367 ALA B CA  1 
ATOM   6522  C C   . ALA B 1 367 ? -21.767 -61.608 -18.759 1.00 107.61 ? 367 ALA B C   1 
ATOM   6523  O O   . ALA B 1 367 ? -21.727 -62.496 -17.909 1.00 106.33 ? 367 ALA B O   1 
ATOM   6524  C CB  . ALA B 1 367 ? -22.781 -59.801 -17.347 1.00 118.09 ? 367 ALA B CB  1 
ATOM   6525  N N   . LYS B 1 368 ? -20.885 -61.509 -19.761 1.00 104.02 ? 368 LYS B N   1 
ATOM   6526  C CA  . LYS B 1 368 ? -19.667 -62.304 -19.814 1.00 97.15  ? 368 LYS B CA  1 
ATOM   6527  C C   . LYS B 1 368 ? -18.740 -61.910 -18.655 1.00 85.83  ? 368 LYS B C   1 
ATOM   6528  O O   . LYS B 1 368 ? -17.669 -62.498 -18.488 1.00 82.84  ? 368 LYS B O   1 
ATOM   6529  C CB  . LYS B 1 368 ? -18.991 -62.122 -21.181 1.00 93.04  ? 368 LYS B CB  1 
ATOM   6530  N N   . ASN B 1 369 ? -19.148 -60.899 -17.868 1.00 70.77  ? 369 ASN B N   1 
ATOM   6531  C CA  . ASN B 1 369 ? -18.483 -60.555 -16.618 1.00 57.77  ? 369 ASN B CA  1 
ATOM   6532  C C   . ASN B 1 369 ? -19.513 -60.464 -15.486 1.00 50.57  ? 369 ASN B C   1 
ATOM   6533  O O   . ASN B 1 369 ? -20.324 -59.537 -15.420 1.00 48.49  ? 369 ASN B O   1 
ATOM   6534  C CB  . ASN B 1 369 ? -17.674 -59.257 -16.734 1.00 58.13  ? 369 ASN B CB  1 
ATOM   6535  C CG  . ASN B 1 369 ? -16.822 -59.001 -15.503 1.00 59.47  ? 369 ASN B CG  1 
ATOM   6536  O OD1 . ASN B 1 369 ? -16.508 -59.926 -14.755 1.00 51.52  ? 369 ASN B OD1 1 
ATOM   6537  N ND2 . ASN B 1 369 ? -16.438 -57.756 -15.282 1.00 57.55  ? 369 ASN B ND2 1 
ATOM   6538  N N   . PRO B 1 370 ? -19.530 -61.439 -14.551 1.00 48.35  ? 370 PRO B N   1 
ATOM   6539  C CA  . PRO B 1 370 ? -20.372 -61.348 -13.348 1.00 45.23  ? 370 PRO B CA  1 
ATOM   6540  C C   . PRO B 1 370 ? -19.706 -60.662 -12.149 1.00 45.26  ? 370 PRO B C   1 
ATOM   6541  O O   . PRO B 1 370 ? -20.290 -60.616 -11.068 1.00 44.42  ? 370 PRO B O   1 
ATOM   6542  C CB  . PRO B 1 370 ? -20.599 -62.829 -13.014 1.00 46.54  ? 370 PRO B CB  1 
ATOM   6543  C CG  . PRO B 1 370 ? -19.292 -63.497 -13.429 1.00 51.79  ? 370 PRO B CG  1 
ATOM   6544  C CD  . PRO B 1 370 ? -18.781 -62.706 -14.629 1.00 47.88  ? 370 PRO B CD  1 
ATOM   6545  N N   . TRP B 1 371 ? -18.471 -60.163 -12.345 1.00 42.47  ? 371 TRP B N   1 
ATOM   6546  C CA  . TRP B 1 371 ? -17.599 -59.755 -11.246 1.00 43.94  ? 371 TRP B CA  1 
ATOM   6547  C C   . TRP B 1 371 ? -17.542 -58.226 -11.083 1.00 39.76  ? 371 TRP B C   1 
ATOM   6548  O O   . TRP B 1 371 ? -17.792 -57.472 -12.020 1.00 44.00  ? 371 TRP B O   1 
ATOM   6549  C CB  . TRP B 1 371 ? -16.190 -60.328 -11.473 1.00 46.93  ? 371 TRP B CB  1 
ATOM   6550  C CG  . TRP B 1 371 ? -16.147 -61.817 -11.589 1.00 49.25  ? 371 TRP B CG  1 
ATOM   6551  C CD1 . TRP B 1 371 ? -15.791 -62.543 -12.695 1.00 56.79  ? 371 TRP B CD1 1 
ATOM   6552  C CD2 . TRP B 1 371 ? -16.469 -62.772 -10.563 1.00 47.08  ? 371 TRP B CD2 1 
ATOM   6553  N NE1 . TRP B 1 371 ? -15.865 -63.883 -12.423 1.00 54.17  ? 371 TRP B NE1 1 
ATOM   6554  C CE2 . TRP B 1 371 ? -16.270 -64.056 -11.123 1.00 55.31  ? 371 TRP B CE2 1 
ATOM   6555  C CE3 . TRP B 1 371 ? -16.875 -62.672 -9.226  1.00 45.03  ? 371 TRP B CE3 1 
ATOM   6556  C CZ2 . TRP B 1 371 ? -16.508 -65.228 -10.396 1.00 51.54  ? 371 TRP B CZ2 1 
ATOM   6557  C CZ3 . TRP B 1 371 ? -17.098 -63.827 -8.506  1.00 51.51  ? 371 TRP B CZ3 1 
ATOM   6558  C CH2 . TRP B 1 371 ? -16.916 -65.086 -9.084  1.00 50.87  ? 371 TRP B CH2 1 
ATOM   6559  N N   . PRO B 1 372 ? -17.128 -57.704 -9.910  1.00 35.94  ? 372 PRO B N   1 
ATOM   6560  C CA  . PRO B 1 372 ? -17.071 -56.261 -9.701  1.00 36.77  ? 372 PRO B CA  1 
ATOM   6561  C C   . PRO B 1 372 ? -15.784 -55.584 -10.186 1.00 41.85  ? 372 PRO B C   1 
ATOM   6562  O O   . PRO B 1 372 ? -14.813 -56.266 -10.554 1.00 41.62  ? 372 PRO B O   1 
ATOM   6563  C CB  . PRO B 1 372 ? -17.244 -56.166 -8.172  1.00 36.79  ? 372 PRO B CB  1 
ATOM   6564  C CG  . PRO B 1 372 ? -16.605 -57.427 -7.615  1.00 36.99  ? 372 PRO B CG  1 
ATOM   6565  C CD  . PRO B 1 372 ? -16.758 -58.460 -8.705  1.00 38.15  ? 372 PRO B CD  1 
ATOM   6566  N N   . ASN B 1 373 ? -15.809 -54.229 -10.169 1.00 43.55  ? 373 ASN B N   1 
ATOM   6567  C CA  . ASN B 1 373 ? -14.645 -53.366 -10.368 1.00 38.00  ? 373 ASN B CA  1 
ATOM   6568  C C   . ASN B 1 373 ? -14.262 -52.644 -9.058  1.00 38.22  ? 373 ASN B C   1 
ATOM   6569  O O   . ASN B 1 373 ? -14.891 -52.798 -8.010  1.00 39.19  ? 373 ASN B O   1 
ATOM   6570  C CB  . ASN B 1 373 ? -14.884 -52.368 -11.514 1.00 43.66  ? 373 ASN B CB  1 
ATOM   6571  C CG  . ASN B 1 373 ? -15.948 -51.309 -11.236 1.00 47.74  ? 373 ASN B CG  1 
ATOM   6572  O OD1 . ASN B 1 373 ? -16.329 -51.029 -10.102 1.00 51.53  ? 373 ASN B OD1 1 
ATOM   6573  N ND2 . ASN B 1 373 ? -16.460 -50.691 -12.282 1.00 52.91  ? 373 ASN B ND2 1 
ATOM   6574  N N   . VAL B 1 374 ? -13.225 -51.792 -9.145  1.00 40.01  ? 374 VAL B N   1 
ATOM   6575  C CA  . VAL B 1 374 ? -12.681 -51.022 -8.029  1.00 37.63  ? 374 VAL B CA  1 
ATOM   6576  C C   . VAL B 1 374 ? -13.741 -50.161 -7.317  1.00 36.33  ? 374 VAL B C   1 
ATOM   6577  O O   . VAL B 1 374 ? -13.723 -50.030 -6.079  1.00 35.04  ? 374 VAL B O   1 
ATOM   6578  C CB  . VAL B 1 374 ? -11.481 -50.192 -8.540  1.00 40.52  ? 374 VAL B CB  1 
ATOM   6579  C CG1 . VAL B 1 374 ? -11.891 -49.088 -9.508  1.00 48.21  ? 374 VAL B CG1 1 
ATOM   6580  C CG2 . VAL B 1 374 ? -10.653 -49.622 -7.399  1.00 44.17  ? 374 VAL B CG2 1 
ATOM   6581  N N   . ASP B 1 375 ? -14.692 -49.584 -8.064  1.00 35.59  ? 375 ASP B N   1 
ATOM   6582  C CA  . ASP B 1 375 ? -15.657 -48.632 -7.508  1.00 37.54  ? 375 ASP B CA  1 
ATOM   6583  C C   . ASP B 1 375 ? -16.745 -49.294 -6.651  1.00 41.80  ? 375 ASP B C   1 
ATOM   6584  O O   . ASP B 1 375 ? -17.468 -48.621 -5.897  1.00 37.25  ? 375 ASP B O   1 
ATOM   6585  C CB  . ASP B 1 375 ? -16.298 -47.832 -8.632  1.00 37.52  ? 375 ASP B CB  1 
ATOM   6586  C CG  . ASP B 1 375 ? -15.263 -47.096 -9.469  1.00 47.97  ? 375 ASP B CG  1 
ATOM   6587  O OD1 . ASP B 1 375 ? -14.396 -46.414 -8.860  1.00 41.25  ? 375 ASP B OD1 1 
ATOM   6588  O OD2 . ASP B 1 375 ? -15.324 -47.223 -10.721 1.00 47.49  ? 375 ASP B OD2 1 
ATOM   6589  N N   . ALA B 1 376 ? -16.882 -50.620 -6.792  1.00 38.07  ? 376 ALA B N   1 
ATOM   6590  C CA  . ALA B 1 376 ? -17.778 -51.397 -5.949  1.00 35.07  ? 376 ALA B CA  1 
ATOM   6591  C C   . ALA B 1 376 ? -17.378 -51.280 -4.475  1.00 37.89  ? 376 ALA B C   1 
ATOM   6592  O O   . ALA B 1 376 ? -18.230 -51.447 -3.600  1.00 38.90  ? 376 ALA B O   1 
ATOM   6593  C CB  . ALA B 1 376 ? -17.798 -52.838 -6.419  1.00 34.03  ? 376 ALA B CB  1 
ATOM   6594  N N   . HIS B 1 377 ? -16.080 -51.038 -4.190  1.00 37.42  ? 377 HIS B N   1 
ATOM   6595  C CA  . HIS B 1 377 ? -15.567 -51.242 -2.838  1.00 38.54  ? 377 HIS B CA  1 
ATOM   6596  C C   . HIS B 1 377 ? -15.074 -49.983 -2.129  1.00 38.69  ? 377 HIS B C   1 
ATOM   6597  O O   . HIS B 1 377 ? -14.957 -50.019 -0.889  1.00 35.12  ? 377 HIS B O   1 
ATOM   6598  C CB  . HIS B 1 377 ? -14.385 -52.224 -2.805  1.00 37.14  ? 377 HIS B CB  1 
ATOM   6599  C CG  . HIS B 1 377 ? -14.414 -53.120 -1.612  1.00 38.47  ? 377 HIS B CG  1 
ATOM   6600  N ND1 . HIS B 1 377 ? -14.429 -52.656 -0.315  1.00 37.91  ? 377 HIS B ND1 1 
ATOM   6601  C CD2 . HIS B 1 377 ? -14.456 -54.458 -1.531  1.00 37.97  ? 377 HIS B CD2 1 
ATOM   6602  C CE1 . HIS B 1 377 ? -14.510 -53.692 0.509   1.00 40.70  ? 377 HIS B CE1 1 
ATOM   6603  N NE2 . HIS B 1 377 ? -14.537 -54.804 -0.215  1.00 37.65  ? 377 HIS B NE2 1 
ATOM   6604  N N   . SER B 1 378 ? -14.672 -48.946 -2.897  1.00 33.81  ? 378 SER B N   1 
ATOM   6605  C CA  . SER B 1 378 ? -13.911 -47.838 -2.321  1.00 32.51  ? 378 SER B CA  1 
ATOM   6606  C C   . SER B 1 378 ? -14.790 -46.985 -1.398  1.00 36.85  ? 378 SER B C   1 
ATOM   6607  O O   . SER B 1 378 ? -14.339 -46.582 -0.335  1.00 37.28  ? 378 SER B O   1 
ATOM   6608  C CB  . SER B 1 378 ? -13.231 -46.984 -3.394  1.00 34.12  ? 378 SER B CB  1 
ATOM   6609  O OG  . SER B 1 378 ? -14.162 -46.516 -4.367  1.00 31.80  ? 378 SER B OG  1 
ATOM   6610  N N   . GLY B 1 379 ? -16.041 -46.698 -1.791  1.00 37.08  ? 379 GLY B N   1 
ATOM   6611  C CA  . GLY B 1 379 ? -16.898 -45.799 -1.026  1.00 34.30  ? 379 GLY B CA  1 
ATOM   6612  C C   . GLY B 1 379 ? -17.127 -46.221 0.439   1.00 37.52  ? 379 GLY B C   1 
ATOM   6613  O O   . GLY B 1 379 ? -17.138 -45.381 1.342   1.00 34.68  ? 379 GLY B O   1 
ATOM   6614  N N   . VAL B 1 380 ? -17.387 -47.507 0.705   1.00 38.44  ? 380 VAL B N   1 
ATOM   6615  C CA  . VAL B 1 380 ? -17.664 -47.920 2.077   1.00 39.32  ? 380 VAL B CA  1 
ATOM   6616  C C   . VAL B 1 380 ? -16.413 -47.761 2.929   1.00 33.51  ? 380 VAL B C   1 
ATOM   6617  O O   . VAL B 1 380 ? -16.530 -47.655 4.142   1.00 36.89  ? 380 VAL B O   1 
ATOM   6618  C CB  . VAL B 1 380 ? -18.189 -49.370 2.174   1.00 41.16  ? 380 VAL B CB  1 
ATOM   6619  C CG1 . VAL B 1 380 ? -19.545 -49.476 1.494   1.00 46.02  ? 380 VAL B CG1 1 
ATOM   6620  C CG2 . VAL B 1 380 ? -17.191 -50.382 1.610   1.00 44.31  ? 380 VAL B CG2 1 
ATOM   6621  N N   . LEU B 1 381 ? -15.224 -47.870 2.323   1.00 31.24  ? 381 LEU B N   1 
ATOM   6622  C CA  . LEU B 1 381 ? -13.987 -47.706 3.072   1.00 38.67  ? 381 LEU B CA  1 
ATOM   6623  C C   . LEU B 1 381 ? -13.860 -46.245 3.524   1.00 41.03  ? 381 LEU B C   1 
ATOM   6624  O O   . LEU B 1 381 ? -13.626 -46.003 4.712   1.00 36.04  ? 381 LEU B O   1 
ATOM   6625  C CB  . LEU B 1 381 ? -12.771 -48.148 2.233   1.00 41.05  ? 381 LEU B CB  1 
ATOM   6626  C CG  . LEU B 1 381 ? -12.657 -49.631 1.877   1.00 45.40  ? 381 LEU B CG  1 
ATOM   6627  C CD1 . LEU B 1 381 ? -11.304 -49.919 1.230   1.00 46.54  ? 381 LEU B CD1 1 
ATOM   6628  C CD2 . LEU B 1 381 ? -12.841 -50.519 3.092   1.00 48.55  ? 381 LEU B CD2 1 
ATOM   6629  N N   . LEU B 1 382 ? -13.996 -45.285 2.577   1.00 34.59  ? 382 LEU B N   1 
ATOM   6630  C CA  . LEU B 1 382 ? -14.016 -43.862 2.914   1.00 34.27  ? 382 LEU B CA  1 
ATOM   6631  C C   . LEU B 1 382 ? -15.101 -43.549 3.948   1.00 34.98  ? 382 LEU B C   1 
ATOM   6632  O O   . LEU B 1 382 ? -14.834 -42.903 4.971   1.00 32.18  ? 382 LEU B O   1 
ATOM   6633  C CB  . LEU B 1 382 ? -14.208 -43.026 1.645   1.00 34.46  ? 382 LEU B CB  1 
ATOM   6634  C CG  . LEU B 1 382 ? -13.076 -43.179 0.631   1.00 36.05  ? 382 LEU B CG  1 
ATOM   6635  C CD1 . LEU B 1 382 ? -13.449 -42.513 -0.685  1.00 38.28  ? 382 LEU B CD1 1 
ATOM   6636  C CD2 . LEU B 1 382 ? -11.756 -42.639 1.187   1.00 40.73  ? 382 LEU B CD2 1 
ATOM   6637  N N   . TRP B 1 383 ? -16.319 -44.027 3.722   1.00 33.45  ? 383 TRP B N   1 
ATOM   6638  C CA  . TRP B 1 383 ? -17.425 -43.678 4.608   1.00 35.36  ? 383 TRP B CA  1 
ATOM   6639  C C   . TRP B 1 383 ? -17.166 -44.225 6.020   1.00 45.58  ? 383 TRP B C   1 
ATOM   6640  O O   . TRP B 1 383 ? -17.486 -43.553 6.995   1.00 38.38  ? 383 TRP B O   1 
ATOM   6641  C CB  . TRP B 1 383 ? -18.747 -44.208 4.069   1.00 38.10  ? 383 TRP B CB  1 
ATOM   6642  C CG  . TRP B 1 383 ? -19.978 -43.830 4.847   1.00 36.00  ? 383 TRP B CG  1 
ATOM   6643  C CD1 . TRP B 1 383 ? -20.477 -44.502 5.923   1.00 41.78  ? 383 TRP B CD1 1 
ATOM   6644  C CD2 . TRP B 1 383 ? -20.879 -42.727 4.624   1.00 36.73  ? 383 TRP B CD2 1 
ATOM   6645  N NE1 . TRP B 1 383 ? -21.625 -43.910 6.372   1.00 34.52  ? 383 TRP B NE1 1 
ATOM   6646  C CE2 . TRP B 1 383 ? -21.904 -42.825 5.600   1.00 36.54  ? 383 TRP B CE2 1 
ATOM   6647  C CE3 . TRP B 1 383 ? -20.944 -41.674 3.698   1.00 38.30  ? 383 TRP B CE3 1 
ATOM   6648  C CZ2 . TRP B 1 383 ? -22.952 -41.914 5.697   1.00 38.38  ? 383 TRP B CZ2 1 
ATOM   6649  C CZ3 . TRP B 1 383 ? -21.988 -40.773 3.783   1.00 37.35  ? 383 TRP B CZ3 1 
ATOM   6650  C CH2 . TRP B 1 383 ? -22.967 -40.886 4.777   1.00 44.26  ? 383 TRP B CH2 1 
ATOM   6651  N N   . HIS B 1 384 ? -16.545 -45.416 6.133   1.00 36.95  ? 384 HIS B N   1 
ATOM   6652  C CA  . HIS B 1 384 ? -16.342 -46.030 7.445   1.00 42.93  ? 384 HIS B CA  1 
ATOM   6653  C C   . HIS B 1 384 ? -15.472 -45.116 8.310   1.00 42.01  ? 384 HIS B C   1 
ATOM   6654  O O   . HIS B 1 384 ? -15.733 -44.946 9.484   1.00 39.01  ? 384 HIS B O   1 
ATOM   6655  C CB  . HIS B 1 384 ? -15.728 -47.443 7.358   1.00 42.11  ? 384 HIS B CB  1 
ATOM   6656  C CG  . HIS B 1 384 ? -15.274 -48.013 8.680   1.00 42.35  ? 384 HIS B CG  1 
ATOM   6657  N ND1 . HIS B 1 384 ? -16.163 -48.475 9.632   1.00 43.45  ? 384 HIS B ND1 1 
ATOM   6658  C CD2 . HIS B 1 384 ? -14.035 -48.170 9.207   1.00 43.90  ? 384 HIS B CD2 1 
ATOM   6659  C CE1 . HIS B 1 384 ? -15.483 -48.913 10.690  1.00 47.52  ? 384 HIS B CE1 1 
ATOM   6660  N NE2 . HIS B 1 384 ? -14.184 -48.732 10.460  1.00 47.31  ? 384 HIS B NE2 1 
ATOM   6661  N N   . TYR B 1 385 ? -14.413 -44.540 7.739   1.00 38.18  ? 385 TYR B N   1 
ATOM   6662  C CA  . TYR B 1 385 ? -13.510 -43.730 8.528   1.00 36.83  ? 385 TYR B CA  1 
ATOM   6663  C C   . TYR B 1 385 ? -13.991 -42.280 8.670   1.00 37.69  ? 385 TYR B C   1 
ATOM   6664  O O   . TYR B 1 385 ? -13.213 -41.440 9.098   1.00 42.46  ? 385 TYR B O   1 
ATOM   6665  C CB  . TYR B 1 385 ? -12.112 -43.840 7.925   1.00 37.46  ? 385 TYR B CB  1 
ATOM   6666  C CG  . TYR B 1 385 ? -11.476 -45.192 8.128   1.00 42.17  ? 385 TYR B CG  1 
ATOM   6667  C CD1 . TYR B 1 385 ? -11.026 -45.576 9.383   1.00 45.22  ? 385 TYR B CD1 1 
ATOM   6668  C CD2 . TYR B 1 385 ? -11.371 -46.107 7.096   1.00 41.65  ? 385 TYR B CD2 1 
ATOM   6669  C CE1 . TYR B 1 385 ? -10.454 -46.821 9.599   1.00 47.29  ? 385 TYR B CE1 1 
ATOM   6670  C CE2 . TYR B 1 385 ? -10.778 -47.345 7.287   1.00 42.88  ? 385 TYR B CE2 1 
ATOM   6671  C CZ  . TYR B 1 385 ? -10.331 -47.711 8.548   1.00 46.47  ? 385 TYR B CZ  1 
ATOM   6672  O OH  . TYR B 1 385 ? -9.742  -48.928 8.792   1.00 51.60  ? 385 TYR B OH  1 
ATOM   6673  N N   . GLY B 1 386 ? -15.239 -41.973 8.305   1.00 39.05  ? 386 GLY B N   1 
ATOM   6674  C CA  . GLY B 1 386 ? -15.813 -40.639 8.476   1.00 38.56  ? 386 GLY B CA  1 
ATOM   6675  C C   . GLY B 1 386 ? -15.585 -39.661 7.303   1.00 36.32  ? 386 GLY B C   1 
ATOM   6676  O O   . GLY B 1 386 ? -15.830 -38.479 7.457   1.00 37.15  ? 386 GLY B O   1 
ATOM   6677  N N   . ILE B 1 387 ? -15.139 -40.108 6.125   1.00 40.72  ? 387 ILE B N   1 
ATOM   6678  C CA  . ILE B 1 387 ? -15.087 -39.227 4.961   1.00 34.97  ? 387 ILE B CA  1 
ATOM   6679  C C   . ILE B 1 387 ? -16.409 -39.404 4.225   1.00 34.32  ? 387 ILE B C   1 
ATOM   6680  O O   . ILE B 1 387 ? -16.584 -40.369 3.489   1.00 31.72  ? 387 ILE B O   1 
ATOM   6681  C CB  . ILE B 1 387 ? -13.854 -39.476 4.054   1.00 38.82  ? 387 ILE B CB  1 
ATOM   6682  C CG1 . ILE B 1 387 ? -12.521 -39.329 4.792   1.00 39.30  ? 387 ILE B CG1 1 
ATOM   6683  C CG2 . ILE B 1 387 ? -13.881 -38.573 2.825   1.00 34.22  ? 387 ILE B CG2 1 
ATOM   6684  C CD1 . ILE B 1 387 ? -11.737 -40.600 4.953   1.00 43.85  ? 387 ILE B CD1 1 
ATOM   6685  N N   . ARG B 1 388 ? -17.338 -38.482 4.464   1.00 33.98  ? 388 ARG B N   1 
ATOM   6686  C CA  . ARG B 1 388 ? -18.735 -38.658 4.126   1.00 39.33  ? 388 ARG B CA  1 
ATOM   6687  C C   . ARG B 1 388 ? -19.240 -37.641 3.100   1.00 37.16  ? 388 ARG B C   1 
ATOM   6688  O O   . ARG B 1 388 ? -20.423 -37.665 2.738   1.00 35.22  ? 388 ARG B O   1 
ATOM   6689  C CB  . ARG B 1 388 ? -19.553 -38.496 5.405   1.00 45.67  ? 388 ARG B CB  1 
ATOM   6690  C CG  . ARG B 1 388 ? -19.099 -39.498 6.444   1.00 50.13  ? 388 ARG B CG  1 
ATOM   6691  C CD  . ARG B 1 388 ? -20.128 -39.867 7.476   1.00 53.47  ? 388 ARG B CD  1 
ATOM   6692  N NE  . ARG B 1 388 ? -19.584 -41.119 8.011   1.00 62.95  ? 388 ARG B NE  1 
ATOM   6693  C CZ  . ARG B 1 388 ? -20.229 -41.941 8.814   1.00 58.32  ? 388 ARG B CZ  1 
ATOM   6694  N NH1 . ARG B 1 388 ? -21.458 -41.643 9.211   1.00 52.13  ? 388 ARG B NH1 1 
ATOM   6695  N NH2 . ARG B 1 388 ? -19.643 -43.062 9.191   1.00 52.65  ? 388 ARG B NH2 1 
ATOM   6696  N N   . GLU B 1 389 ? -18.343 -36.788 2.609   1.00 32.98  ? 389 GLU B N   1 
ATOM   6697  C CA  . GLU B 1 389 ? -18.724 -35.725 1.694   1.00 33.62  ? 389 GLU B CA  1 
ATOM   6698  C C   . GLU B 1 389 ? -18.619 -36.259 0.276   1.00 34.04  ? 389 GLU B C   1 
ATOM   6699  O O   . GLU B 1 389 ? -17.550 -36.193 -0.334  1.00 33.99  ? 389 GLU B O   1 
ATOM   6700  C CB  . GLU B 1 389 ? -17.825 -34.525 1.993   1.00 37.43  ? 389 GLU B CB  1 
ATOM   6701  C CG  . GLU B 1 389 ? -17.994 -34.004 3.431   1.00 37.58  ? 389 GLU B CG  1 
ATOM   6702  C CD  . GLU B 1 389 ? -17.278 -34.732 4.572   1.00 36.93  ? 389 GLU B CD  1 
ATOM   6703  O OE1 . GLU B 1 389 ? -17.566 -34.393 5.741   1.00 37.05  ? 389 GLU B OE1 1 
ATOM   6704  O OE2 . GLU B 1 389 ? -16.426 -35.633 4.313   1.00 38.45  ? 389 GLU B OE2 1 
ATOM   6705  N N   . TYR B 1 390 ? -19.725 -36.839 -0.220  1.00 31.09  ? 390 TYR B N   1 
ATOM   6706  C CA  . TYR B 1 390 ? -19.756 -37.508 -1.517  1.00 38.50  ? 390 TYR B CA  1 
ATOM   6707  C C   . TYR B 1 390 ? -19.051 -36.730 -2.637  1.00 34.90  ? 390 TYR B C   1 
ATOM   6708  O O   . TYR B 1 390 ? -18.316 -37.335 -3.417  1.00 33.86  ? 390 TYR B O   1 
ATOM   6709  C CB  . TYR B 1 390 ? -21.187 -37.758 -2.019  1.00 38.71  ? 390 TYR B CB  1 
ATOM   6710  C CG  . TYR B 1 390 ? -22.013 -38.652 -1.135  1.00 43.60  ? 390 TYR B CG  1 
ATOM   6711  C CD1 . TYR B 1 390 ? -21.958 -40.040 -1.255  1.00 48.10  ? 390 TYR B CD1 1 
ATOM   6712  C CD2 . TYR B 1 390 ? -22.884 -38.106 -0.211  1.00 41.47  ? 390 TYR B CD2 1 
ATOM   6713  C CE1 . TYR B 1 390 ? -22.727 -40.867 -0.451  1.00 45.42  ? 390 TYR B CE1 1 
ATOM   6714  C CE2 . TYR B 1 390 ? -23.636 -38.918 0.622   1.00 47.91  ? 390 TYR B CE2 1 
ATOM   6715  C CZ  . TYR B 1 390 ? -23.569 -40.296 0.487   1.00 44.87  ? 390 TYR B CZ  1 
ATOM   6716  O OH  . TYR B 1 390 ? -24.334 -41.075 1.305   1.00 42.16  ? 390 TYR B OH  1 
ATOM   6717  N N   . ASP B 1 391 ? -19.338 -35.429 -2.780  1.00 37.37  ? 391 ASP B N   1 
ATOM   6718  C CA  . ASP B 1 391 ? -18.796 -34.641 -3.897  1.00 38.33  ? 391 ASP B CA  1 
ATOM   6719  C C   . ASP B 1 391 ? -17.267 -34.703 -3.935  1.00 34.26  ? 391 ASP B C   1 
ATOM   6720  O O   . ASP B 1 391 ? -16.639 -34.827 -5.016  1.00 31.17  ? 391 ASP B O   1 
ATOM   6721  C CB  . ASP B 1 391 ? -19.280 -33.194 -3.824  1.00 41.25  ? 391 ASP B CB  1 
ATOM   6722  C CG  . ASP B 1 391 ? -20.751 -33.052 -4.169  1.00 45.79  ? 391 ASP B CG  1 
ATOM   6723  O OD1 . ASP B 1 391 ? -21.340 -34.065 -4.603  1.00 44.01  ? 391 ASP B OD1 1 
ATOM   6724  O OD2 . ASP B 1 391 ? -21.309 -31.954 -3.974  1.00 51.61  ? 391 ASP B OD2 1 
ATOM   6725  N N   . PHE B 1 392 ? -16.700 -34.763 -2.721  1.00 27.51  ? 392 PHE B N   1 
ATOM   6726  C CA  . PHE B 1 392 ? -15.266 -34.714 -2.532  1.00 27.74  ? 392 PHE B CA  1 
ATOM   6727  C C   . PHE B 1 392 ? -14.579 -36.005 -2.947  1.00 29.91  ? 392 PHE B C   1 
ATOM   6728  O O   . PHE B 1 392 ? -13.377 -35.981 -3.213  1.00 29.68  ? 392 PHE B O   1 
ATOM   6729  C CB  . PHE B 1 392 ? -14.919 -34.405 -1.071  1.00 27.72  ? 392 PHE B CB  1 
ATOM   6730  C CG  . PHE B 1 392 ? -13.458 -34.061 -0.903  1.00 27.18  ? 392 PHE B CG  1 
ATOM   6731  C CD1 . PHE B 1 392 ? -12.977 -32.814 -1.263  1.00 29.52  ? 392 PHE B CD1 1 
ATOM   6732  C CD2 . PHE B 1 392 ? -12.565 -34.978 -0.377  1.00 29.57  ? 392 PHE B CD2 1 
ATOM   6733  C CE1 . PHE B 1 392 ? -11.637 -32.466 -1.092  1.00 27.10  ? 392 PHE B CE1 1 
ATOM   6734  C CE2 . PHE B 1 392 ? -11.216 -34.657 -0.251  1.00 29.54  ? 392 PHE B CE2 1 
ATOM   6735  C CZ  . PHE B 1 392 ? -10.756 -33.387 -0.570  1.00 27.41  ? 392 PHE B CZ  1 
ATOM   6736  N N   . TYR B 1 393 ? -15.338 -37.106 -3.099  1.00 29.70  ? 393 TYR B N   1 
ATOM   6737  C CA  . TYR B 1 393 ? -14.737 -38.395 -3.449  1.00 27.08  ? 393 TYR B CA  1 
ATOM   6738  C C   . TYR B 1 393 ? -13.985 -38.324 -4.762  1.00 28.74  ? 393 TYR B C   1 
ATOM   6739  O O   . TYR B 1 393 ? -12.963 -39.003 -4.963  1.00 26.45  ? 393 TYR B O   1 
ATOM   6740  C CB  . TYR B 1 393 ? -15.815 -39.486 -3.544  1.00 29.50  ? 393 TYR B CB  1 
ATOM   6741  C CG  . TYR B 1 393 ? -16.347 -39.967 -2.223  1.00 30.98  ? 393 TYR B CG  1 
ATOM   6742  C CD1 . TYR B 1 393 ? -16.150 -39.279 -1.038  1.00 34.57  ? 393 TYR B CD1 1 
ATOM   6743  C CD2 . TYR B 1 393 ? -17.001 -41.186 -2.153  1.00 42.06  ? 393 TYR B CD2 1 
ATOM   6744  C CE1 . TYR B 1 393 ? -16.626 -39.754 0.173   1.00 35.82  ? 393 TYR B CE1 1 
ATOM   6745  C CE2 . TYR B 1 393 ? -17.472 -41.690 -0.952  1.00 37.49  ? 393 TYR B CE2 1 
ATOM   6746  C CZ  . TYR B 1 393 ? -17.249 -40.996 0.215   1.00 39.74  ? 393 TYR B CZ  1 
ATOM   6747  O OH  . TYR B 1 393 ? -17.767 -41.525 1.352   1.00 35.18  ? 393 TYR B OH  1 
ATOM   6748  N N   . THR B 1 394 ? -14.521 -37.507 -5.673  1.00 24.65  ? 394 THR B N   1 
ATOM   6749  C CA  . THR B 1 394 ? -13.907 -37.370 -6.972  1.00 27.12  ? 394 THR B CA  1 
ATOM   6750  C C   . THR B 1 394 ? -12.568 -36.643 -6.845  1.00 27.85  ? 394 THR B C   1 
ATOM   6751  O O   . THR B 1 394 ? -11.664 -36.890 -7.631  1.00 25.58  ? 394 THR B O   1 
ATOM   6752  C CB  . THR B 1 394 ? -14.806 -36.628 -7.969  1.00 27.52  ? 394 THR B CB  1 
ATOM   6753  O OG1 . THR B 1 394 ? -16.103 -37.211 -7.967  1.00 29.54  ? 394 THR B OG1 1 
ATOM   6754  C CG2 . THR B 1 394 ? -14.286 -36.761 -9.385  1.00 29.27  ? 394 THR B CG2 1 
ATOM   6755  N N   . VAL B 1 395 ? -12.429 -35.763 -5.842  1.00 27.52  ? 395 VAL B N   1 
ATOM   6756  C CA  . VAL B 1 395 ? -11.145 -35.105 -5.635  1.00 27.00  ? 395 VAL B CA  1 
ATOM   6757  C C   . VAL B 1 395 ? -10.080 -36.124 -5.203  1.00 24.53  ? 395 VAL B C   1 
ATOM   6758  O O   . VAL B 1 395 ? -8.961  -36.110 -5.713  1.00 25.94  ? 395 VAL B O   1 
ATOM   6759  C CB  . VAL B 1 395 ? -11.267 -33.928 -4.655  1.00 26.25  ? 395 VAL B CB  1 
ATOM   6760  C CG1 . VAL B 1 395 ? -9.910  -33.296 -4.413  1.00 26.89  ? 395 VAL B CG1 1 
ATOM   6761  C CG2 . VAL B 1 395 ? -12.271 -32.900 -5.145  1.00 26.33  ? 395 VAL B CG2 1 
ATOM   6762  N N   . LEU B 1 396 ? -10.422 -37.056 -4.314  1.00 27.17  ? 396 LEU B N   1 
ATOM   6763  C CA  . LEU B 1 396 ? -9.471  -38.089 -3.881  1.00 26.22  ? 396 LEU B CA  1 
ATOM   6764  C C   . LEU B 1 396 ? -9.030  -38.930 -5.086  1.00 28.93  ? 396 LEU B C   1 
ATOM   6765  O O   . LEU B 1 396 ? -7.862  -39.315 -5.244  1.00 28.69  ? 396 LEU B O   1 
ATOM   6766  C CB  . LEU B 1 396 ? -10.121 -38.967 -2.796  1.00 26.18  ? 396 LEU B CB  1 
ATOM   6767  C CG  . LEU B 1 396 ? -10.510 -38.239 -1.505  1.00 31.99  ? 396 LEU B CG  1 
ATOM   6768  C CD1 . LEU B 1 396 ? -11.335 -39.084 -0.561  1.00 35.34  ? 396 LEU B CD1 1 
ATOM   6769  C CD2 . LEU B 1 396 ? -9.264  -37.724 -0.803  1.00 29.83  ? 396 LEU B CD2 1 
ATOM   6770  N N   . PHE B 1 397 ? -9.991  -39.229 -5.957  1.00 28.62  ? 397 PHE B N   1 
ATOM   6771  C CA  . PHE B 1 397 ? -9.712  -39.979 -7.171  1.00 26.13  ? 397 PHE B CA  1 
ATOM   6772  C C   . PHE B 1 397 ? -8.710  -39.208 -8.007  1.00 26.88  ? 397 PHE B C   1 
ATOM   6773  O O   . PHE B 1 397 ? -7.721  -39.769 -8.481  1.00 28.79  ? 397 PHE B O   1 
ATOM   6774  C CB  . PHE B 1 397 ? -11.047 -40.263 -7.876  1.00 29.33  ? 397 PHE B CB  1 
ATOM   6775  C CG  . PHE B 1 397 ? -11.027 -41.142 -9.102  1.00 33.49  ? 397 PHE B CG  1 
ATOM   6776  C CD1 . PHE B 1 397 ? -9.895  -41.810 -9.531  1.00 38.88  ? 397 PHE B CD1 1 
ATOM   6777  C CD2 . PHE B 1 397 ? -12.206 -41.336 -9.818  1.00 44.67  ? 397 PHE B CD2 1 
ATOM   6778  C CE1 . PHE B 1 397 ? -9.933  -42.635 -10.653 1.00 41.34  ? 397 PHE B CE1 1 
ATOM   6779  C CE2 . PHE B 1 397 ? -12.247 -42.166 -10.937 1.00 39.69  ? 397 PHE B CE2 1 
ATOM   6780  C CZ  . PHE B 1 397 ? -11.100 -42.805 -11.357 1.00 40.77  ? 397 PHE B CZ  1 
ATOM   6781  N N   . GLY B 1 398 ? -8.975  -37.899 -8.163  1.00 27.81  ? 398 GLY B N   1 
ATOM   6782  C CA  . GLY B 1 398 ? -8.090  -37.025 -8.907  1.00 23.77  ? 398 GLY B CA  1 
ATOM   6783  C C   . GLY B 1 398 ? -6.670  -36.976 -8.362  1.00 22.87  ? 398 GLY B C   1 
ATOM   6784  O O   . GLY B 1 398 ? -5.710  -37.058 -9.135  1.00 25.04  ? 398 GLY B O   1 
ATOM   6785  N N   . VAL B 1 399 ? -6.509  -36.832 -7.041  1.00 24.27  ? 399 VAL B N   1 
ATOM   6786  C CA  . VAL B 1 399 ? -5.166  -36.813 -6.466  1.00 24.75  ? 399 VAL B CA  1 
ATOM   6787  C C   . VAL B 1 399 ? -4.415  -38.089 -6.865  1.00 25.64  ? 399 VAL B C   1 
ATOM   6788  O O   . VAL B 1 399 ? -3.241  -38.040 -7.205  1.00 31.04  ? 399 VAL B O   1 
ATOM   6789  C CB  . VAL B 1 399 ? -5.237  -36.676 -4.935  1.00 26.69  ? 399 VAL B CB  1 
ATOM   6790  C CG1 . VAL B 1 399 ? -3.904  -36.926 -4.267  1.00 27.62  ? 399 VAL B CG1 1 
ATOM   6791  C CG2 . VAL B 1 399 ? -5.813  -35.328 -4.495  1.00 29.64  ? 399 VAL B CG2 1 
ATOM   6792  N N   . SER B 1 400 ? -5.082  -39.249 -6.756  1.00 27.55  ? 400 SER B N   1 
ATOM   6793  C CA  . SER B 1 400 ? -4.492  -40.525 -7.104  1.00 27.97  ? 400 SER B CA  1 
ATOM   6794  C C   . SER B 1 400 ? -4.095  -40.576 -8.575  1.00 24.59  ? 400 SER B C   1 
ATOM   6795  O O   . SER B 1 400 ? -2.999  -40.986 -8.931  1.00 27.62  ? 400 SER B O   1 
ATOM   6796  C CB  . SER B 1 400 ? -5.427  -41.659 -6.797  1.00 32.76  ? 400 SER B CB  1 
ATOM   6797  O OG  . SER B 1 400 ? -4.838  -42.893 -7.210  1.00 32.63  ? 400 SER B OG  1 
ATOM   6798  N N   . ARG B 1 401 ? -5.021  -40.189 -9.441  1.00 25.64  ? 401 ARG B N   1 
ATOM   6799  C CA  . ARG B 1 401 ? -4.856  -40.365 -10.883 1.00 27.92  ? 401 ARG B CA  1 
ATOM   6800  C C   . ARG B 1 401 ? -3.745  -39.450 -11.407 1.00 28.82  ? 401 ARG B C   1 
ATOM   6801  O O   . ARG B 1 401 ? -3.202  -39.649 -12.497 1.00 29.38  ? 401 ARG B O   1 
ATOM   6802  C CB  . ARG B 1 401 ? -6.269  -40.153 -11.463 1.00 31.70  ? 401 ARG B CB  1 
ATOM   6803  C CG  . ARG B 1 401 ? -6.504  -40.595 -12.896 1.00 38.95  ? 401 ARG B CG  1 
ATOM   6804  C CD  . ARG B 1 401 ? -5.936  -41.951 -13.314 1.00 37.36  ? 401 ARG B CD  1 
ATOM   6805  N NE  . ARG B 1 401 ? -6.592  -43.062 -12.671 1.00 41.48  ? 401 ARG B NE  1 
ATOM   6806  C CZ  . ARG B 1 401 ? -7.578  -43.799 -13.182 1.00 43.61  ? 401 ARG B CZ  1 
ATOM   6807  N NH1 . ARG B 1 401 ? -8.315  -43.353 -14.186 1.00 42.63  ? 401 ARG B NH1 1 
ATOM   6808  N NH2 . ARG B 1 401 ? -7.883  -44.945 -12.603 1.00 44.24  ? 401 ARG B NH2 1 
ATOM   6809  N N   . ALA B 1 402 ? -3.356  -38.451 -10.589 1.00 29.55  ? 402 ALA B N   1 
ATOM   6810  C CA  . ALA B 1 402 ? -2.222  -37.591 -10.894 1.00 29.71  ? 402 ALA B CA  1 
ATOM   6811  C C   . ALA B 1 402 ? -0.911  -38.360 -11.012 1.00 25.87  ? 402 ALA B C   1 
ATOM   6812  O O   . ALA B 1 402 ? -0.052  -37.997 -11.822 1.00 27.73  ? 402 ALA B O   1 
ATOM   6813  C CB  . ALA B 1 402 ? -2.109  -36.507 -9.850  1.00 28.00  ? 402 ALA B CB  1 
ATOM   6814  N N   . LEU B 1 403 ? -0.750  -39.425 -10.222 1.00 26.83  ? 403 LEU B N   1 
ATOM   6815  C CA  . LEU B 1 403 ? 0.430   -40.290 -10.318 1.00 27.78  ? 403 LEU B CA  1 
ATOM   6816  C C   . LEU B 1 403 ? 0.595   -40.853 -11.737 1.00 27.01  ? 403 LEU B C   1 
ATOM   6817  O O   . LEU B 1 403 ? 1.622   -40.658 -12.395 1.00 31.34  ? 403 LEU B O   1 
ATOM   6818  C CB  . LEU B 1 403 ? 0.273   -41.427 -9.306  1.00 31.34  ? 403 LEU B CB  1 
ATOM   6819  C CG  . LEU B 1 403 ? 0.273   -40.996 -7.838  1.00 33.57  ? 403 LEU B CG  1 
ATOM   6820  C CD1 . LEU B 1 403 ? -0.280  -42.099 -6.953  1.00 36.21  ? 403 LEU B CD1 1 
ATOM   6821  C CD2 . LEU B 1 403 ? 1.669   -40.585 -7.385  1.00 33.54  ? 403 LEU B CD2 1 
ATOM   6822  N N   . GLY B 1 404 ? -0.439  -41.495 -12.249 1.00 27.81  ? 404 GLY B N   1 
ATOM   6823  C CA  . GLY B 1 404 ? -0.366  -42.032 -13.609 1.00 30.73  ? 404 GLY B CA  1 
ATOM   6824  C C   . GLY B 1 404 ? -0.350  -40.957 -14.704 1.00 29.53  ? 404 GLY B C   1 
ATOM   6825  O O   . GLY B 1 404 ? 0.358   -41.092 -15.694 1.00 27.15  ? 404 GLY B O   1 
ATOM   6826  N N   . CYS B 1 405 ? -1.079  -39.848 -14.520 1.00 27.90  ? 405 CYS B N   1 
ATOM   6827  C CA  . CYS B 1 405 ? -1.082  -38.785 -15.516 1.00 27.89  ? 405 CYS B CA  1 
ATOM   6828  C C   . CYS B 1 405 ? 0.284   -38.136 -15.656 1.00 26.36  ? 405 CYS B C   1 
ATOM   6829  O O   . CYS B 1 405 ? 0.672   -37.793 -16.777 1.00 26.40  ? 405 CYS B O   1 
ATOM   6830  C CB  . CYS B 1 405 ? -2.146  -37.718 -15.241 1.00 35.31  ? 405 CYS B CB  1 
ATOM   6831  S SG  . CYS B 1 405 ? -3.850  -38.267 -15.579 1.00 42.30  ? 405 CYS B SG  1 
ATOM   6832  N N   . THR B 1 406 ? 0.969   -37.890 -14.527 1.00 26.32  ? 406 THR B N   1 
ATOM   6833  C CA  . THR B 1 406 ? 2.267   -37.244 -14.559 1.00 26.16  ? 406 THR B CA  1 
ATOM   6834  C C   . THR B 1 406 ? 3.282   -38.197 -15.209 1.00 26.06  ? 406 THR B C   1 
ATOM   6835  O O   . THR B 1 406 ? 4.065   -37.775 -16.034 1.00 28.55  ? 406 THR B O   1 
ATOM   6836  C CB  . THR B 1 406 ? 2.770   -36.765 -13.193 1.00 27.43  ? 406 THR B CB  1 
ATOM   6837  O OG1 . THR B 1 406 ? 2.771   -37.872 -12.306 1.00 26.21  ? 406 THR B OG1 1 
ATOM   6838  C CG2 . THR B 1 406 ? 1.965   -35.610 -12.600 1.00 25.69  ? 406 THR B CG2 1 
ATOM   6839  N N   . ALA B 1 407 ? 3.229   -39.483 -14.885 1.00 28.23  ? 407 ALA B N   1 
ATOM   6840  C CA  . ALA B 1 407 ? 4.115   -40.473 -15.486 1.00 29.82  ? 407 ALA B CA  1 
ATOM   6841  C C   . ALA B 1 407 ? 3.926   -40.517 -17.003 1.00 30.65  ? 407 ALA B C   1 
ATOM   6842  O O   . ALA B 1 407 ? 4.898   -40.440 -17.763 1.00 35.23  ? 407 ALA B O   1 
ATOM   6843  C CB  . ALA B 1 407 ? 3.808   -41.804 -14.861 1.00 32.33  ? 407 ALA B CB  1 
ATOM   6844  N N   . GLN B 1 408 ? 2.660   -40.608 -17.433 1.00 29.60  ? 408 GLN B N   1 
ATOM   6845  C CA  . GLN B 1 408 ? 2.342   -40.644 -18.854 1.00 32.17  ? 408 GLN B CA  1 
ATOM   6846  C C   . GLN B 1 408 ? 2.885   -39.409 -19.560 1.00 33.86  ? 408 GLN B C   1 
ATOM   6847  O O   . GLN B 1 408 ? 3.497   -39.497 -20.632 1.00 30.43  ? 408 GLN B O   1 
ATOM   6848  C CB  . GLN B 1 408 ? 0.828   -40.799 -19.055 1.00 33.70  ? 408 GLN B CB  1 
ATOM   6849  C CG  . GLN B 1 408 ? 0.318   -42.183 -18.691 1.00 35.48  ? 408 GLN B CG  1 
ATOM   6850  C CD  . GLN B 1 408 ? -1.142  -42.429 -19.021 1.00 44.06  ? 408 GLN B CD  1 
ATOM   6851  O OE1 . GLN B 1 408 ? -1.903  -42.996 -18.237 1.00 39.88  ? 408 GLN B OE1 1 
ATOM   6852  N NE2 . GLN B 1 408 ? -1.536  -42.079 -20.234 1.00 44.85  ? 408 GLN B NE2 1 
ATOM   6853  N N   . ALA B 1 409 ? 2.672   -38.236 -18.947 1.00 30.70  ? 409 ALA B N   1 
ATOM   6854  C CA  . ALA B 1 409 ? 3.042   -36.991 -19.582 1.00 31.83  ? 409 ALA B CA  1 
ATOM   6855  C C   . ALA B 1 409 ? 4.565   -36.896 -19.688 1.00 27.87  ? 409 ALA B C   1 
ATOM   6856  O O   . ALA B 1 409 ? 5.101   -36.438 -20.697 1.00 33.36  ? 409 ALA B O   1 
ATOM   6857  C CB  . ALA B 1 409 ? 2.417   -35.828 -18.819 1.00 35.60  ? 409 ALA B CB  1 
ATOM   6858  N N   . ILE B 1 410 ? 5.274   -37.334 -18.666 1.00 30.25  ? 410 ILE B N   1 
ATOM   6859  C CA  . ILE B 1 410 ? 6.738   -37.320 -18.724 1.00 29.90  ? 410 ILE B CA  1 
ATOM   6860  C C   . ILE B 1 410 ? 7.230   -38.251 -19.837 1.00 30.92  ? 410 ILE B C   1 
ATOM   6861  O O   . ILE B 1 410 ? 8.095   -37.875 -20.619 1.00 30.90  ? 410 ILE B O   1 
ATOM   6862  C CB  . ILE B 1 410 ? 7.348   -37.704 -17.365 1.00 30.18  ? 410 ILE B CB  1 
ATOM   6863  C CG1 . ILE B 1 410 ? 6.963   -36.676 -16.281 1.00 30.57  ? 410 ILE B CG1 1 
ATOM   6864  C CG2 . ILE B 1 410 ? 8.855   -37.833 -17.501 1.00 30.68  ? 410 ILE B CG2 1 
ATOM   6865  C CD1 . ILE B 1 410 ? 7.225   -37.088 -14.864 1.00 31.35  ? 410 ILE B CD1 1 
ATOM   6866  N N   . LEU B 1 411 ? 6.709   -39.473 -19.876 1.00 34.84  ? 411 LEU B N   1 
ATOM   6867  C CA  . LEU B 1 411 ? 7.140   -40.469 -20.857 1.00 32.95  ? 411 LEU B CA  1 
ATOM   6868  C C   . LEU B 1 411 ? 6.882   -40.028 -22.303 1.00 36.62  ? 411 LEU B C   1 
ATOM   6869  O O   . LEU B 1 411 ? 7.762   -40.187 -23.152 1.00 35.83  ? 411 LEU B O   1 
ATOM   6870  C CB  . LEU B 1 411 ? 6.408   -41.763 -20.527 1.00 36.98  ? 411 LEU B CB  1 
ATOM   6871  C CG  . LEU B 1 411 ? 6.876   -42.424 -19.223 1.00 34.75  ? 411 LEU B CG  1 
ATOM   6872  C CD1 . LEU B 1 411 ? 6.020   -43.639 -18.875 1.00 36.05  ? 411 LEU B CD1 1 
ATOM   6873  C CD2 . LEU B 1 411 ? 8.318   -42.839 -19.346 1.00 36.47  ? 411 LEU B CD2 1 
ATOM   6874  N N   . VAL B 1 412 ? 5.699   -39.475 -22.612 1.00 31.09  ? 412 VAL B N   1 
ATOM   6875  C CA  . VAL B 1 412 ? 5.388   -39.202 -24.006 1.00 31.31  ? 412 VAL B CA  1 
ATOM   6876  C C   . VAL B 1 412 ? 6.209   -38.003 -24.472 1.00 30.29  ? 412 VAL B C   1 
ATOM   6877  O O   . VAL B 1 412 ? 6.532   -37.907 -25.655 1.00 33.53  ? 412 VAL B O   1 
ATOM   6878  C CB  . VAL B 1 412 ? 3.874   -39.067 -24.310 1.00 35.66  ? 412 VAL B CB  1 
ATOM   6879  C CG1 . VAL B 1 412 ? 3.105   -40.334 -23.960 1.00 41.43  ? 412 VAL B CG1 1 
ATOM   6880  C CG2 . VAL B 1 412 ? 3.232   -37.868 -23.624 1.00 37.34  ? 412 VAL B CG2 1 
ATOM   6881  N N   . ARG B 1 413 ? 6.567   -37.090 -23.568 1.00 27.51  ? 413 ARG B N   1 
ATOM   6882  C CA  . ARG B 1 413 ? 7.483   -36.022 -23.946 1.00 32.78  ? 413 ARG B CA  1 
ATOM   6883  C C   . ARG B 1 413 ? 8.896   -36.573 -24.099 1.00 31.47  ? 413 ARG B C   1 
ATOM   6884  O O   . ARG B 1 413 ? 9.646   -36.041 -24.921 1.00 39.38  ? 413 ARG B O   1 
ATOM   6885  C CB  . ARG B 1 413 ? 7.392   -34.822 -23.006 1.00 32.77  ? 413 ARG B CB  1 
ATOM   6886  C CG  . ARG B 1 413 ? 5.985   -34.245 -22.920 1.00 34.31  ? 413 ARG B CG  1 
ATOM   6887  C CD  . ARG B 1 413 ? 5.670   -33.155 -23.930 1.00 33.53  ? 413 ARG B CD  1 
ATOM   6888  N NE  . ARG B 1 413 ? 6.079   -33.468 -25.289 1.00 39.49  ? 413 ARG B NE  1 
ATOM   6889  C CZ  . ARG B 1 413 ? 5.423   -34.234 -26.168 1.00 38.19  ? 413 ARG B CZ  1 
ATOM   6890  N NH1 . ARG B 1 413 ? 4.232   -34.724 -25.895 1.00 34.39  ? 413 ARG B NH1 1 
ATOM   6891  N NH2 . ARG B 1 413 ? 5.989   -34.536 -27.321 1.00 33.70  ? 413 ARG B NH2 1 
ATOM   6892  N N   . GLY B 1 414 ? 9.244   -37.627 -23.343 1.00 30.68  ? 414 GLY B N   1 
ATOM   6893  C CA  . GLY B 1 414 ? 10.478  -38.372 -23.572 1.00 32.32  ? 414 GLY B CA  1 
ATOM   6894  C C   . GLY B 1 414 ? 10.547  -39.079 -24.933 1.00 32.02  ? 414 GLY B C   1 
ATOM   6895  O O   . GLY B 1 414 ? 11.584  -39.024 -25.604 1.00 35.03  ? 414 GLY B O   1 
ATOM   6896  N N   . TYR B 1 415 ? 9.416   -39.676 -25.364 1.00 33.67  ? 415 TYR B N   1 
ATOM   6897  C CA  . TYR B 1 415 ? 9.274   -40.324 -26.661 1.00 37.14  ? 415 TYR B CA  1 
ATOM   6898  C C   . TYR B 1 415 ? 9.179   -39.353 -27.848 1.00 36.41  ? 415 TYR B C   1 
ATOM   6899  O O   . TYR B 1 415 ? 9.402   -39.737 -29.007 1.00 37.62  ? 415 TYR B O   1 
ATOM   6900  C CB  . TYR B 1 415 ? 7.980   -41.132 -26.741 1.00 35.77  ? 415 TYR B CB  1 
ATOM   6901  C CG  . TYR B 1 415 ? 7.804   -42.281 -25.780 1.00 33.54  ? 415 TYR B CG  1 
ATOM   6902  C CD1 . TYR B 1 415 ? 8.763   -42.655 -24.844 1.00 35.38  ? 415 TYR B CD1 1 
ATOM   6903  C CD2 . TYR B 1 415 ? 6.628   -43.000 -25.817 1.00 35.55  ? 415 TYR B CD2 1 
ATOM   6904  C CE1 . TYR B 1 415 ? 8.530   -43.709 -23.971 1.00 35.33  ? 415 TYR B CE1 1 
ATOM   6905  C CE2 . TYR B 1 415 ? 6.383   -44.054 -24.953 1.00 36.24  ? 415 TYR B CE2 1 
ATOM   6906  C CZ  . TYR B 1 415 ? 7.335   -44.405 -24.014 1.00 37.39  ? 415 TYR B CZ  1 
ATOM   6907  O OH  . TYR B 1 415 ? 7.039   -45.461 -23.152 1.00 35.46  ? 415 TYR B OH  1 
ATOM   6908  N N   . MET B 1 416 ? 8.771   -38.115 -27.562 1.00 33.49  ? 416 MET B N   1 
ATOM   6909  C CA  . MET B 1 416 ? 8.522   -37.077 -28.556 1.00 33.15  ? 416 MET B CA  1 
ATOM   6910  C C   . MET B 1 416 ? 7.386   -37.462 -29.500 1.00 32.24  ? 416 MET B C   1 
ATOM   6911  O O   . MET B 1 416 ? 7.434   -37.155 -30.682 1.00 33.84  ? 416 MET B O   1 
ATOM   6912  C CB  . MET B 1 416 ? 9.795   -36.771 -29.343 1.00 37.81  ? 416 MET B CB  1 
ATOM   6913  C CG  . MET B 1 416 ? 10.957  -36.489 -28.388 1.00 42.31  ? 416 MET B CG  1 
ATOM   6914  S SD  . MET B 1 416 ? 12.378  -35.773 -29.223 1.00 51.91  ? 416 MET B SD  1 
ATOM   6915  C CE  . MET B 1 416 ? 13.493  -35.526 -27.847 1.00 49.98  ? 416 MET B CE  1 
ATOM   6916  N N   . LEU B 1 417 ? 6.310   -38.033 -28.957 1.00 34.13  ? 417 LEU B N   1 
ATOM   6917  C CA  . LEU B 1 417 ? 5.085   -38.212 -29.731 1.00 37.70  ? 417 LEU B CA  1 
ATOM   6918  C C   . LEU B 1 417 ? 4.538   -36.865 -30.210 1.00 40.21  ? 417 LEU B C   1 
ATOM   6919  O O   . LEU B 1 417 ? 4.704   -35.840 -29.553 1.00 36.65  ? 417 LEU B O   1 
ATOM   6920  C CB  . LEU B 1 417 ? 4.050   -38.945 -28.882 1.00 33.03  ? 417 LEU B CB  1 
ATOM   6921  C CG  . LEU B 1 417 ? 4.479   -40.342 -28.440 1.00 36.17  ? 417 LEU B CG  1 
ATOM   6922  C CD1 . LEU B 1 417 ? 3.290   -41.114 -27.899 1.00 34.36  ? 417 LEU B CD1 1 
ATOM   6923  C CD2 . LEU B 1 417 ? 5.146   -41.079 -29.605 1.00 37.05  ? 417 LEU B CD2 1 
ATOM   6924  N N   . PRO B 1 418 ? 3.936   -36.819 -31.417 1.00 36.11  ? 418 PRO B N   1 
ATOM   6925  C CA  . PRO B 1 418 ? 3.442   -35.567 -31.986 1.00 34.86  ? 418 PRO B CA  1 
ATOM   6926  C C   . PRO B 1 418 ? 2.082   -35.122 -31.456 1.00 34.26  ? 418 PRO B C   1 
ATOM   6927  O O   . PRO B 1 418 ? 1.425   -35.813 -30.669 1.00 31.13  ? 418 PRO B O   1 
ATOM   6928  C CB  . PRO B 1 418 ? 3.361   -35.933 -33.484 1.00 35.68  ? 418 PRO B CB  1 
ATOM   6929  C CG  . PRO B 1 418 ? 2.902   -37.364 -33.433 1.00 32.87  ? 418 PRO B CG  1 
ATOM   6930  C CD  . PRO B 1 418 ? 3.764   -37.959 -32.335 1.00 35.55  ? 418 PRO B CD  1 
ATOM   6931  N N   . ILE B 1 419 ? 1.646   -33.951 -31.919 1.00 33.83  ? 419 ILE B N   1 
ATOM   6932  C CA  . ILE B 1 419 ? 0.367   -33.398 -31.513 1.00 29.38  ? 419 ILE B CA  1 
ATOM   6933  C C   . ILE B 1 419 ? -0.770  -34.344 -31.890 1.00 35.90  ? 419 ILE B C   1 
ATOM   6934  O O   . ILE B 1 419 ? -0.809  -34.932 -32.968 1.00 32.79  ? 419 ILE B O   1 
ATOM   6935  C CB  . ILE B 1 419 ? 0.177   -32.017 -32.144 1.00 32.72  ? 419 ILE B CB  1 
ATOM   6936  C CG1 . ILE B 1 419 ? -1.009  -31.294 -31.503 1.00 29.21  ? 419 ILE B CG1 1 
ATOM   6937  C CG2 . ILE B 1 419 ? 0.071   -32.095 -33.669 1.00 35.90  ? 419 ILE B CG2 1 
ATOM   6938  C CD1 . ILE B 1 419 ? -1.059  -29.822 -31.817 1.00 32.56  ? 419 ILE B CD1 1 
ATOM   6939  N N   . GLU B 1 420 ? -1.746  -34.495 -31.005 1.00 35.35  ? 420 GLU B N   1 
ATOM   6940  C CA  . GLU B 1 420 ? -2.864  -35.351 -31.352 1.00 37.13  ? 420 GLU B CA  1 
ATOM   6941  C C   . GLU B 1 420 ? -3.848  -34.561 -32.226 1.00 39.26  ? 420 GLU B C   1 
ATOM   6942  O O   . GLU B 1 420 ? -4.289  -33.477 -31.846 1.00 36.59  ? 420 GLU B O   1 
ATOM   6943  C CB  . GLU B 1 420 ? -3.414  -35.948 -30.059 1.00 36.37  ? 420 GLU B CB  1 
ATOM   6944  C CG  . GLU B 1 420 ? -4.648  -36.797 -30.292 1.00 41.25  ? 420 GLU B CG  1 
ATOM   6945  C CD  . GLU B 1 420 ? -5.257  -37.340 -29.014 1.00 46.81  ? 420 GLU B CD  1 
ATOM   6946  O OE1 . GLU B 1 420 ? -6.487  -37.560 -29.004 1.00 46.69  ? 420 GLU B OE1 1 
ATOM   6947  O OE2 . GLU B 1 420 ? -4.506  -37.502 -28.018 1.00 49.20  ? 420 GLU B OE2 1 
ATOM   6948  N N   . ARG B 1 421 ? -4.161  -35.075 -33.436 1.00 35.15  ? 421 ARG B N   1 
ATOM   6949  C CA  . ARG B 1 421 ? -4.982  -34.354 -34.402 1.00 37.90  ? 421 ARG B CA  1 
ATOM   6950  C C   . ARG B 1 421 ? -5.697  -35.358 -35.316 1.00 40.18  ? 421 ARG B C   1 
ATOM   6951  O O   . ARG B 1 421 ? -5.309  -35.580 -36.467 1.00 42.75  ? 421 ARG B O   1 
ATOM   6952  C CB  . ARG B 1 421 ? -4.151  -33.337 -35.200 1.00 42.83  ? 421 ARG B CB  1 
ATOM   6953  C CG  . ARG B 1 421 ? -4.929  -32.108 -35.683 1.00 49.17  ? 421 ARG B CG  1 
ATOM   6954  C CD  . ARG B 1 421 ? -5.753  -32.192 -36.969 1.00 56.35  ? 421 ARG B CD  1 
ATOM   6955  N NE  . ARG B 1 421 ? -6.379  -30.922 -37.391 1.00 67.36  ? 421 ARG B NE  1 
ATOM   6956  C CZ  . ARG B 1 421 ? -7.655  -30.756 -37.782 1.00 64.19  ? 421 ARG B CZ  1 
ATOM   6957  N NH1 . ARG B 1 421 ? -8.081  -29.559 -38.159 1.00 61.80  ? 421 ARG B NH1 1 
ATOM   6958  N NH2 . ARG B 1 421 ? -8.506  -31.774 -37.803 1.00 60.35  ? 421 ARG B NH2 1 
ATOM   6959  N N   . PRO B 1 422 ? -6.786  -35.979 -34.823 1.00 33.59  ? 422 PRO B N   1 
ATOM   6960  C CA  . PRO B 1 422 ? -7.646  -36.792 -35.676 1.00 35.70  ? 422 PRO B CA  1 
ATOM   6961  C C   . PRO B 1 422 ? -8.417  -35.976 -36.719 1.00 34.48  ? 422 PRO B C   1 
ATOM   6962  O O   . PRO B 1 422 ? -8.424  -34.749 -36.691 1.00 33.90  ? 422 PRO B O   1 
ATOM   6963  C CB  . PRO B 1 422 ? -8.596  -37.483 -34.697 1.00 33.14  ? 422 PRO B CB  1 
ATOM   6964  C CG  . PRO B 1 422 ? -8.596  -36.601 -33.459 1.00 38.52  ? 422 PRO B CG  1 
ATOM   6965  C CD  . PRO B 1 422 ? -7.253  -35.898 -33.434 1.00 33.34  ? 422 PRO B CD  1 
ATOM   6966  N N   . LYS B 1 423 ? -9.056  -36.695 -37.646 1.00 33.98  ? 423 LYS B N   1 
ATOM   6967  C CA  . LYS B 1 423 ? -9.889  -36.129 -38.691 1.00 35.67  ? 423 LYS B CA  1 
ATOM   6968  C C   . LYS B 1 423 ? -11.350 -36.289 -38.273 1.00 31.92  ? 423 LYS B C   1 
ATOM   6969  O O   . LYS B 1 423 ? -11.751 -37.356 -37.811 1.00 35.80  ? 423 LYS B O   1 
ATOM   6970  C CB  . LYS B 1 423 ? -9.527  -36.871 -39.985 1.00 40.36  ? 423 LYS B CB  1 
ATOM   6971  C CG  . LYS B 1 423 ? -10.301 -36.471 -41.231 1.00 48.19  ? 423 LYS B CG  1 
ATOM   6972  C CD  . LYS B 1 423 ? -10.031 -35.055 -41.677 1.00 60.20  ? 423 LYS B CD  1 
ATOM   6973  C CE  . LYS B 1 423 ? -11.071 -34.543 -42.653 1.00 68.68  ? 423 LYS B CE  1 
ATOM   6974  N NZ  . LYS B 1 423 ? -10.789 -33.144 -43.047 1.00 74.55  ? 423 LYS B NZ  1 
ATOM   6975  N N   . SER B 1 424 ? -12.150 -35.219 -38.380 1.00 33.50  ? 424 SER B N   1 
ATOM   6976  C CA  . SER B 1 424 ? -13.559 -35.334 -38.070 1.00 37.64  ? 424 SER B CA  1 
ATOM   6977  C C   . SER B 1 424 ? -14.297 -35.559 -39.388 1.00 35.49  ? 424 SER B C   1 
ATOM   6978  O O   . SER B 1 424 ? -13.776 -35.211 -40.427 1.00 34.12  ? 424 SER B O   1 
ATOM   6979  C CB  . SER B 1 424 ? -14.082 -34.132 -37.297 1.00 40.89  ? 424 SER B CB  1 
ATOM   6980  O OG  . SER B 1 424 ? -13.931 -32.941 -38.041 1.00 39.84  ? 424 SER B OG  1 
ATOM   6981  N N   . ILE B 1 425 ? -15.486 -36.155 -39.318 1.00 37.09  ? 425 ILE B N   1 
ATOM   6982  C CA  . ILE B 1 425 ? -16.343 -36.358 -40.490 1.00 40.97  ? 425 ILE B CA  1 
ATOM   6983  C C   . ILE B 1 425 ? -17.701 -35.710 -40.263 1.00 38.35  ? 425 ILE B C   1 
ATOM   6984  O O   . ILE B 1 425 ? -18.131 -35.513 -39.115 1.00 35.72  ? 425 ILE B O   1 
ATOM   6985  C CB  . ILE B 1 425 ? -16.512 -37.865 -40.781 1.00 41.55  ? 425 ILE B CB  1 
ATOM   6986  C CG1 . ILE B 1 425 ? -17.174 -38.610 -39.610 1.00 41.05  ? 425 ILE B CG1 1 
ATOM   6987  C CG2 . ILE B 1 425 ? -15.164 -38.472 -41.151 1.00 46.28  ? 425 ILE B CG2 1 
ATOM   6988  C CD1 . ILE B 1 425 ? -17.461 -40.099 -39.887 1.00 44.22  ? 425 ILE B CD1 1 
ATOM   6989  N N   . THR B 1 426 ? -18.383 -35.386 -41.371 1.00 35.85  ? 426 THR B N   1 
ATOM   6990  C CA  . THR B 1 426 ? -19.712 -34.797 -41.303 1.00 35.22  ? 426 THR B CA  1 
ATOM   6991  C C   . THR B 1 426 ? -20.780 -35.845 -41.564 1.00 40.95  ? 426 THR B C   1 
ATOM   6992  O O   . THR B 1 426 ? -20.547 -36.817 -42.285 1.00 44.05  ? 426 THR B O   1 
ATOM   6993  C CB  . THR B 1 426 ? -19.904 -33.655 -42.310 1.00 40.65  ? 426 THR B CB  1 
ATOM   6994  O OG1 . THR B 1 426 ? -19.734 -34.212 -43.611 1.00 41.44  ? 426 THR B OG1 1 
ATOM   6995  C CG2 . THR B 1 426 ? -18.960 -32.489 -42.095 1.00 37.81  ? 426 THR B CG2 1 
ATOM   6996  N N   . THR B 1 427 ? -21.959 -35.596 -40.985 1.00 40.47  ? 427 THR B N   1 
ATOM   6997  C CA  . THR B 1 427 ? -23.132 -36.428 -41.197 1.00 44.88  ? 427 THR B CA  1 
ATOM   6998  C C   . THR B 1 427 ? -23.563 -36.349 -42.662 1.00 49.32  ? 427 THR B C   1 
ATOM   6999  O O   . THR B 1 427 ? -24.000 -37.347 -43.228 1.00 45.30  ? 427 THR B O   1 
ATOM   7000  C CB  . THR B 1 427 ? -24.235 -36.035 -40.219 1.00 42.83  ? 427 THR B CB  1 
ATOM   7001  O OG1 . THR B 1 427 ? -23.605 -36.087 -38.943 1.00 44.60  ? 427 THR B OG1 1 
ATOM   7002  C CG2 . THR B 1 427 ? -25.449 -36.941 -40.251 1.00 43.15  ? 427 THR B CG2 1 
ATOM   7003  N N   . ARG B 1 428 ? -23.390 -35.178 -43.281 1.00 47.84  ? 428 ARG B N   1 
ATOM   7004  C CA  . ARG B 1 428 ? -23.633 -35.013 -44.707 1.00 55.11  ? 428 ARG B CA  1 
ATOM   7005  C C   . ARG B 1 428 ? -22.828 -36.026 -45.519 1.00 56.54  ? 428 ARG B C   1 
ATOM   7006  O O   . ARG B 1 428 ? -23.406 -36.761 -46.316 1.00 58.67  ? 428 ARG B O   1 
ATOM   7007  C CB  . ARG B 1 428 ? -23.264 -33.602 -45.163 1.00 63.10  ? 428 ARG B CB  1 
ATOM   7008  C CG  . ARG B 1 428 ? -23.476 -33.353 -46.649 1.00 72.28  ? 428 ARG B CG  1 
ATOM   7009  C CD  . ARG B 1 428 ? -22.625 -32.187 -47.107 1.00 86.58  ? 428 ARG B CD  1 
ATOM   7010  N NE  . ARG B 1 428 ? -22.930 -31.754 -48.462 1.00 109.72 ? 428 ARG B NE  1 
ATOM   7011  C CZ  . ARG B 1 428 ? -24.060 -31.160 -48.845 1.00 108.97 ? 428 ARG B CZ  1 
ATOM   7012  N NH1 . ARG B 1 428 ? -25.041 -30.967 -47.979 1.00 107.42 ? 428 ARG B NH1 1 
ATOM   7013  N NH2 . ARG B 1 428 ? -24.202 -30.764 -50.101 1.00 101.74 ? 428 ARG B NH2 1 
ATOM   7014  N N   . TRP B 1 429 ? -21.497 -36.025 -45.360 1.00 51.62  ? 429 TRP B N   1 
ATOM   7015  C CA  . TRP B 1 429 ? -20.648 -37.009 -46.014 1.00 53.63  ? 429 TRP B CA  1 
ATOM   7016  C C   . TRP B 1 429 ? -21.150 -38.425 -45.725 1.00 58.78  ? 429 TRP B C   1 
ATOM   7017  O O   . TRP B 1 429 ? -21.408 -39.198 -46.648 1.00 55.36  ? 429 TRP B O   1 
ATOM   7018  C CB  . TRP B 1 429 ? -19.200 -36.862 -45.558 1.00 51.77  ? 429 TRP B CB  1 
ATOM   7019  C CG  . TRP B 1 429 ? -18.231 -37.817 -46.179 1.00 53.04  ? 429 TRP B CG  1 
ATOM   7020  C CD1 . TRP B 1 429 ? -17.672 -37.716 -47.421 1.00 54.81  ? 429 TRP B CD1 1 
ATOM   7021  C CD2 . TRP B 1 429 ? -17.618 -38.966 -45.565 1.00 53.17  ? 429 TRP B CD2 1 
ATOM   7022  N NE1 . TRP B 1 429 ? -16.769 -38.722 -47.624 1.00 50.04  ? 429 TRP B NE1 1 
ATOM   7023  C CE2 . TRP B 1 429 ? -16.711 -39.505 -46.511 1.00 50.62  ? 429 TRP B CE2 1 
ATOM   7024  C CE3 . TRP B 1 429 ? -17.769 -39.617 -44.334 1.00 48.04  ? 429 TRP B CE3 1 
ATOM   7025  C CZ2 . TRP B 1 429 ? -15.960 -40.653 -46.264 1.00 54.46  ? 429 TRP B CZ2 1 
ATOM   7026  C CZ3 . TRP B 1 429 ? -17.001 -40.734 -44.075 1.00 50.57  ? 429 TRP B CZ3 1 
ATOM   7027  C CH2 . TRP B 1 429 ? -16.111 -41.244 -45.030 1.00 53.87  ? 429 TRP B CH2 1 
ATOM   7028  N N   . VAL B 1 430 ? -21.325 -38.756 -44.441 1.00 50.19  ? 430 VAL B N   1 
ATOM   7029  C CA  . VAL B 1 430 ? -21.795 -40.086 -44.067 1.00 49.65  ? 430 VAL B CA  1 
ATOM   7030  C C   . VAL B 1 430 ? -23.043 -40.471 -44.876 1.00 49.87  ? 430 VAL B C   1 
ATOM   7031  O O   . VAL B 1 430 ? -23.067 -41.528 -45.491 1.00 47.50  ? 430 VAL B O   1 
ATOM   7032  C CB  . VAL B 1 430 ? -22.058 -40.212 -42.555 1.00 52.05  ? 430 VAL B CB  1 
ATOM   7033  C CG1 . VAL B 1 430 ? -22.774 -41.513 -42.228 1.00 51.78  ? 430 VAL B CG1 1 
ATOM   7034  C CG2 . VAL B 1 430 ? -20.775 -40.080 -41.734 1.00 50.86  ? 430 VAL B CG2 1 
ATOM   7035  N N   . LYS B 1 431 ? -24.085 -39.633 -44.858 1.00 56.90  ? 431 LYS B N   1 
ATOM   7036  C CA  . LYS B 1 431 ? -25.328 -39.915 -45.561 1.00 56.38  ? 431 LYS B CA  1 
ATOM   7037  C C   . LYS B 1 431 ? -25.069 -40.143 -47.055 1.00 57.41  ? 431 LYS B C   1 
ATOM   7038  O O   . LYS B 1 431 ? -25.690 -41.002 -47.665 1.00 61.85  ? 431 LYS B O   1 
ATOM   7039  C CB  . LYS B 1 431 ? -26.331 -38.777 -45.366 1.00 55.64  ? 431 LYS B CB  1 
ATOM   7040  C CG  . LYS B 1 431 ? -27.028 -38.748 -44.019 1.00 56.22  ? 431 LYS B CG  1 
ATOM   7041  C CD  . LYS B 1 431 ? -28.115 -37.699 -43.953 1.00 66.25  ? 431 LYS B CD  1 
ATOM   7042  C CE  . LYS B 1 431 ? -29.316 -38.052 -44.807 1.00 70.30  ? 431 LYS B CE  1 
ATOM   7043  N NZ  . LYS B 1 431 ? -30.273 -36.927 -44.882 1.00 76.94  ? 431 LYS B NZ  1 
ATOM   7044  N N   . GLU B 1 432 ? -24.151 -39.379 -47.645 1.00 59.41  ? 432 GLU B N   1 
ATOM   7045  C CA  . GLU B 1 432 ? -23.833 -39.538 -49.052 1.00 69.45  ? 432 GLU B CA  1 
ATOM   7046  C C   . GLU B 1 432 ? -23.186 -40.898 -49.311 1.00 71.64  ? 432 GLU B C   1 
ATOM   7047  O O   . GLU B 1 432 ? -23.517 -41.556 -50.289 1.00 72.06  ? 432 GLU B O   1 
ATOM   7048  C CB  . GLU B 1 432 ? -22.884 -38.438 -49.537 1.00 72.28  ? 432 GLU B CB  1 
ATOM   7049  C CG  . GLU B 1 432 ? -22.656 -38.474 -51.039 1.00 82.73  ? 432 GLU B CG  1 
ATOM   7050  C CD  . GLU B 1 432 ? -21.819 -37.336 -51.598 1.00 93.29  ? 432 GLU B CD  1 
ATOM   7051  O OE1 . GLU B 1 432 ? -22.379 -36.520 -52.362 1.00 97.94  ? 432 GLU B OE1 1 
ATOM   7052  O OE2 . GLU B 1 432 ? -20.610 -37.276 -51.281 1.00 88.42  ? 432 GLU B OE2 1 
ATOM   7053  N N   . VAL B 1 433 ? -22.258 -41.309 -48.442 1.00 64.42  ? 433 VAL B N   1 
ATOM   7054  C CA  . VAL B 1 433 ? -21.213 -42.245 -48.823 1.00 56.08  ? 433 VAL B CA  1 
ATOM   7055  C C   . VAL B 1 433 ? -21.422 -43.610 -48.173 1.00 48.92  ? 433 VAL B C   1 
ATOM   7056  O O   . VAL B 1 433 ? -20.727 -44.549 -48.517 1.00 53.35  ? 433 VAL B O   1 
ATOM   7057  C CB  . VAL B 1 433 ? -19.846 -41.627 -48.479 1.00 57.36  ? 433 VAL B CB  1 
ATOM   7058  C CG1 . VAL B 1 433 ? -18.825 -42.624 -47.954 1.00 63.02  ? 433 VAL B CG1 1 
ATOM   7059  C CG2 . VAL B 1 433 ? -19.289 -40.853 -49.662 1.00 60.89  ? 433 VAL B CG2 1 
ATOM   7060  N N   . ALA B 1 434 ? -22.383 -43.733 -47.253 1.00 54.81  ? 434 ALA B N   1 
ATOM   7061  C CA  . ALA B 1 434 ? -22.439 -44.880 -46.359 1.00 58.46  ? 434 ALA B CA  1 
ATOM   7062  C C   . ALA B 1 434 ? -22.778 -46.153 -47.138 1.00 63.18  ? 434 ALA B C   1 
ATOM   7063  O O   . ALA B 1 434 ? -22.151 -47.196 -46.925 1.00 48.68  ? 434 ALA B O   1 
ATOM   7064  C CB  . ALA B 1 434 ? -23.441 -44.632 -45.258 1.00 62.01  ? 434 ALA B CB  1 
ATOM   7065  N N   . GLU B 1 435 ? -23.763 -46.050 -48.043 1.00 63.85  ? 435 GLU B N   1 
ATOM   7066  C CA  . GLU B 1 435 ? -24.119 -47.136 -48.960 1.00 64.87  ? 435 GLU B CA  1 
ATOM   7067  C C   . GLU B 1 435 ? -22.882 -47.658 -49.688 1.00 51.95  ? 435 GLU B C   1 
ATOM   7068  O O   . GLU B 1 435 ? -22.718 -48.859 -49.810 1.00 56.73  ? 435 GLU B O   1 
ATOM   7069  C CB  . GLU B 1 435 ? -25.140 -46.690 -50.011 1.00 62.93  ? 435 GLU B CB  1 
ATOM   7070  C CG  . GLU B 1 435 ? -26.498 -46.286 -49.443 1.00 71.55  ? 435 GLU B CG  1 
ATOM   7071  C CD  . GLU B 1 435 ? -27.430 -47.407 -49.009 1.00 78.08  ? 435 GLU B CD  1 
ATOM   7072  O OE1 . GLU B 1 435 ? -27.154 -48.046 -47.981 1.00 78.75  ? 435 GLU B OE1 1 
ATOM   7073  O OE2 . GLU B 1 435 ? -28.451 -47.621 -49.697 1.00 84.63  ? 435 GLU B OE2 1 
ATOM   7074  N N   . SER B 1 436 ? -22.023 -46.742 -50.154 1.00 58.09  ? 436 SER B N   1 
ATOM   7075  C CA  . SER B 1 436 ? -20.772 -47.035 -50.853 1.00 55.04  ? 436 SER B CA  1 
ATOM   7076  C C   . SER B 1 436 ? -19.801 -47.862 -50.016 1.00 56.34  ? 436 SER B C   1 
ATOM   7077  O O   . SER B 1 436 ? -18.878 -48.442 -50.569 1.00 61.96  ? 436 SER B O   1 
ATOM   7078  C CB  . SER B 1 436 ? -20.065 -45.745 -51.216 1.00 65.61  ? 436 SER B CB  1 
ATOM   7079  O OG  . SER B 1 436 ? -20.973 -44.748 -51.670 1.00 74.76  ? 436 SER B OG  1 
ATOM   7080  N N   . LEU B 1 437 ? -19.903 -47.768 -48.680 1.00 54.59  ? 437 LEU B N   1 
ATOM   7081  C CA  . LEU B 1 437 ? -18.915 -48.342 -47.783 1.00 53.27  ? 437 LEU B CA  1 
ATOM   7082  C C   . LEU B 1 437 ? -19.221 -49.817 -47.530 1.00 45.55  ? 437 LEU B C   1 
ATOM   7083  O O   . LEU B 1 437 ? -20.377 -50.193 -47.306 1.00 49.12  ? 437 LEU B O   1 
ATOM   7084  C CB  . LEU B 1 437 ? -18.941 -47.585 -46.448 1.00 53.58  ? 437 LEU B CB  1 
ATOM   7085  C CG  . LEU B 1 437 ? -17.889 -46.496 -46.217 1.00 60.74  ? 437 LEU B CG  1 
ATOM   7086  C CD1 . LEU B 1 437 ? -17.494 -45.757 -47.483 1.00 58.11  ? 437 LEU B CD1 1 
ATOM   7087  C CD2 . LEU B 1 437 ? -18.406 -45.512 -45.175 1.00 56.06  ? 437 LEU B CD2 1 
ATOM   7088  N N   . PRO B 1 438 ? -18.178 -50.672 -47.484 1.00 40.79  ? 438 PRO B N   1 
ATOM   7089  C CA  . PRO B 1 438 ? -18.332 -52.078 -47.090 1.00 43.68  ? 438 PRO B CA  1 
ATOM   7090  C C   . PRO B 1 438 ? -18.638 -52.293 -45.614 1.00 47.38  ? 438 PRO B C   1 
ATOM   7091  O O   . PRO B 1 438 ? -18.244 -51.481 -44.777 1.00 55.35  ? 438 PRO B O   1 
ATOM   7092  C CB  . PRO B 1 438 ? -16.952 -52.682 -47.379 1.00 41.84  ? 438 PRO B CB  1 
ATOM   7093  C CG  . PRO B 1 438 ? -16.020 -51.511 -47.292 1.00 45.86  ? 438 PRO B CG  1 
ATOM   7094  C CD  . PRO B 1 438 ? -16.794 -50.334 -47.846 1.00 40.27  ? 438 PRO B CD  1 
ATOM   7095  N N   . VAL B 1 439 ? -19.351 -53.369 -45.288 1.00 43.57  ? 439 VAL B N   1 
ATOM   7096  C CA  . VAL B 1 439 ? -19.489 -53.750 -43.893 1.00 51.31  ? 439 VAL B CA  1 
ATOM   7097  C C   . VAL B 1 439 ? -18.129 -54.270 -43.416 1.00 52.78  ? 439 VAL B C   1 
ATOM   7098  O O   . VAL B 1 439 ? -17.390 -54.876 -44.182 1.00 50.85  ? 439 VAL B O   1 
ATOM   7099  C CB  . VAL B 1 439 ? -20.669 -54.710 -43.628 1.00 55.53  ? 439 VAL B CB  1 
ATOM   7100  C CG1 . VAL B 1 439 ? -20.895 -55.697 -44.758 1.00 67.35  ? 439 VAL B CG1 1 
ATOM   7101  C CG2 . VAL B 1 439 ? -20.543 -55.437 -42.287 1.00 51.89  ? 439 VAL B CG2 1 
ATOM   7102  N N   . ALA B 1 440 ? -17.726 -53.879 -42.193 1.00 50.52  ? 440 ALA B N   1 
ATOM   7103  C CA  . ALA B 1 440 ? -16.426 -54.259 -41.661 1.00 46.68  ? 440 ALA B CA  1 
ATOM   7104  C C   . ALA B 1 440 ? -16.408 -55.777 -41.493 1.00 41.91  ? 440 ALA B C   1 
ATOM   7105  O O   . ALA B 1 440 ? -17.416 -56.365 -41.115 1.00 45.37  ? 440 ALA B O   1 
ATOM   7106  C CB  . ALA B 1 440 ? -16.173 -53.570 -40.336 1.00 52.91  ? 440 ALA B CB  1 
ATOM   7107  N N   . GLY B 1 441 ? -15.258 -56.394 -41.765 1.00 43.08  ? 441 GLY B N   1 
ATOM   7108  C CA  . GLY B 1 441 ? -15.129 -57.846 -41.712 1.00 54.17  ? 441 GLY B CA  1 
ATOM   7109  C C   . GLY B 1 441 ? -15.879 -58.584 -42.838 1.00 57.80  ? 441 GLY B C   1 
ATOM   7110  O O   . GLY B 1 441 ? -15.897 -59.807 -42.859 1.00 52.71  ? 441 GLY B O   1 
ATOM   7111  N N   . SER B 1 442 ? -16.504 -57.878 -43.793 1.00 60.42  ? 442 SER B N   1 
ATOM   7112  C CA  . SER B 1 442 ? -17.256 -58.560 -44.847 1.00 58.15  ? 442 SER B CA  1 
ATOM   7113  C C   . SER B 1 442 ? -16.330 -58.933 -46.004 1.00 57.84  ? 442 SER B C   1 
ATOM   7114  O O   . SER B 1 442 ? -15.196 -58.448 -46.078 1.00 44.09  ? 442 SER B O   1 
ATOM   7115  C CB  . SER B 1 442 ? -18.403 -57.736 -45.349 1.00 50.78  ? 442 SER B CB  1 
ATOM   7116  O OG  . SER B 1 442 ? -17.941 -56.640 -46.132 1.00 39.20  ? 442 SER B OG  1 
ATOM   7117  N N   . LYS B 1 443 ? -16.841 -59.779 -46.919 1.00 51.74  ? 443 LYS B N   1 
ATOM   7118  C CA  . LYS B 1 443 ? -16.084 -60.121 -48.116 1.00 50.83  ? 443 LYS B CA  1 
ATOM   7119  C C   . LYS B 1 443 ? -15.840 -58.865 -48.956 1.00 39.65  ? 443 LYS B C   1 
ATOM   7120  O O   . LYS B 1 443 ? -14.760 -58.687 -49.484 1.00 43.81  ? 443 LYS B O   1 
ATOM   7121  C CB  . LYS B 1 443 ? -16.808 -61.204 -48.896 1.00 57.56  ? 443 LYS B CB  1 
ATOM   7122  N N   . LEU B 1 444 ? -16.835 -57.971 -49.085 1.00 42.45  ? 444 LEU B N   1 
ATOM   7123  C CA  . LEU B 1 444 ? -16.611 -56.749 -49.855 1.00 45.01  ? 444 LEU B CA  1 
ATOM   7124  C C   . LEU B 1 444 ? -15.458 -55.931 -49.244 1.00 49.11  ? 444 LEU B C   1 
ATOM   7125  O O   . LEU B 1 444 ? -14.581 -55.461 -49.981 1.00 45.20  ? 444 LEU B O   1 
ATOM   7126  C CB  . LEU B 1 444 ? -17.884 -55.945 -49.972 1.00 40.11  ? 444 LEU B CB  1 
ATOM   7127  N N   . ALA B 1 445 ? -15.437 -55.804 -47.897 1.00 47.55  ? 445 ALA B N   1 
ATOM   7128  C CA  . ALA B 1 445 ? -14.366 -55.116 -47.179 1.00 47.35  ? 445 ALA B CA  1 
ATOM   7129  C C   . ALA B 1 445 ? -13.013 -55.724 -47.541 1.00 42.01  ? 445 ALA B C   1 
ATOM   7130  O O   . ALA B 1 445 ? -12.054 -55.007 -47.763 1.00 41.42  ? 445 ALA B O   1 
ATOM   7131  C CB  . ALA B 1 445 ? -14.605 -55.179 -45.679 1.00 51.21  ? 445 ALA B CB  1 
ATOM   7132  N N   . ALA B 1 446 ? -12.938 -57.065 -47.570 1.00 44.18  ? 446 ALA B N   1 
ATOM   7133  C CA  . ALA B 1 446 ? -11.732 -57.754 -48.014 1.00 48.85  ? 446 ALA B CA  1 
ATOM   7134  C C   . ALA B 1 446 ? -11.393 -57.340 -49.443 1.00 45.71  ? 446 ALA B C   1 
ATOM   7135  O O   . ALA B 1 446 ? -10.230 -57.173 -49.769 1.00 43.99  ? 446 ALA B O   1 
ATOM   7136  C CB  . ALA B 1 446 ? -11.915 -59.248 -47.918 1.00 50.00  ? 446 ALA B CB  1 
ATOM   7137  N N   . ALA B 1 447 ? -12.412 -57.161 -50.288 1.00 51.96  ? 447 ALA B N   1 
ATOM   7138  C CA  . ALA B 1 447 ? -12.188 -56.774 -51.678 1.00 60.00  ? 447 ALA B CA  1 
ATOM   7139  C C   . ALA B 1 447 ? -11.598 -55.366 -51.755 1.00 62.11  ? 447 ALA B C   1 
ATOM   7140  O O   . ALA B 1 447 ? -10.595 -55.141 -52.418 1.00 72.66  ? 447 ALA B O   1 
ATOM   7141  C CB  . ALA B 1 447 ? -13.475 -56.865 -52.460 1.00 54.59  ? 447 ALA B CB  1 
ATOM   7142  N N   . LEU B 1 448 ? -12.213 -54.421 -51.045 1.00 60.80  ? 448 LEU B N   1 
ATOM   7143  C CA  . LEU B 1 448 ? -11.754 -53.042 -51.039 1.00 61.66  ? 448 LEU B CA  1 
ATOM   7144  C C   . LEU B 1 448 ? -10.488 -52.873 -50.181 1.00 69.17  ? 448 LEU B C   1 
ATOM   7145  O O   . LEU B 1 448 ? -9.937  -51.771 -50.113 1.00 68.21  ? 448 LEU B O   1 
ATOM   7146  C CB  . LEU B 1 448 ? -12.898 -52.152 -50.584 1.00 60.64  ? 448 LEU B CB  1 
ATOM   7147  N N   . GLU B 1 449 ? -9.995  -53.940 -49.521 1.00 62.25  ? 449 GLU B N   1 
ATOM   7148  C CA  . GLU B 1 449 ? -8.732  -53.836 -48.795 1.00 61.01  ? 449 GLU B CA  1 
ATOM   7149  C C   . GLU B 1 449 ? -7.578  -53.726 -49.803 1.00 51.65  ? 449 GLU B C   1 
ATOM   7150  O O   . GLU B 1 449 ? -6.922  -54.766 -50.030 1.00 54.38  ? 449 GLU B O   1 
ATOM   7151  C CB  . GLU B 1 449 ? -8.535  -54.994 -47.828 1.00 52.20  ? 449 GLU B CB  1 
ATOM   7152  N N   . MET C 1 1   ? 19.411  -1.566  27.920  1.00 60.55  ? 1   MET C N   1 
ATOM   7153  C CA  . MET C 1 1   ? 20.308  -1.685  26.740  1.00 50.32  ? 1   MET C CA  1 
ATOM   7154  C C   . MET C 1 1   ? 21.439  -0.663  26.932  1.00 45.26  ? 1   MET C C   1 
ATOM   7155  O O   . MET C 1 1   ? 21.180  0.519   27.153  1.00 41.15  ? 1   MET C O   1 
ATOM   7156  C CB  . MET C 1 1   ? 19.499  -1.438  25.454  1.00 53.72  ? 1   MET C CB  1 
ATOM   7157  C CG  . MET C 1 1   ? 20.289  -1.560  24.155  1.00 60.17  ? 1   MET C CG  1 
ATOM   7158  S SD  . MET C 1 1   ? 19.293  -1.195  22.638  1.00 59.94  ? 1   MET C SD  1 
ATOM   7159  C CE  . MET C 1 1   ? 18.773  0.485   22.973  1.00 56.57  ? 1   MET C CE  1 
ATOM   7160  N N   . LYS C 1 2   ? 22.684  -1.143  26.928  1.00 42.67  ? 2   LYS C N   1 
ATOM   7161  C CA  . LYS C 1 2   ? 23.853  -0.291  27.124  1.00 44.99  ? 2   LYS C CA  1 
ATOM   7162  C C   . LYS C 1 2   ? 23.883  0.860   26.112  1.00 43.31  ? 2   LYS C C   1 
ATOM   7163  O O   . LYS C 1 2   ? 24.226  2.006   26.417  1.00 40.25  ? 2   LYS C O   1 
ATOM   7164  C CB  . LYS C 1 2   ? 25.105  -1.156  26.980  1.00 51.09  ? 2   LYS C CB  1 
ATOM   7165  C CG  . LYS C 1 2   ? 26.419  -0.386  26.931  1.00 59.50  ? 2   LYS C CG  1 
ATOM   7166  C CD  . LYS C 1 2   ? 26.871  0.117   28.278  1.00 70.92  ? 2   LYS C CD  1 
ATOM   7167  C CE  . LYS C 1 2   ? 28.245  0.750   28.208  1.00 80.54  ? 2   LYS C CE  1 
ATOM   7168  N NZ  . LYS C 1 2   ? 28.895  0.741   29.538  1.00 93.45  ? 2   LYS C NZ  1 
ATOM   7169  N N   . LEU C 1 3   ? 23.514  0.557   24.873  1.00 42.23  ? 3   LEU C N   1 
ATOM   7170  C CA  . LEU C 1 3   ? 23.515  1.575   23.838  1.00 36.07  ? 3   LEU C CA  1 
ATOM   7171  C C   . LEU C 1 3   ? 22.767  2.806   24.318  1.00 35.04  ? 3   LEU C C   1 
ATOM   7172  O O   . LEU C 1 3   ? 23.249  3.915   24.148  1.00 38.14  ? 3   LEU C O   1 
ATOM   7173  C CB  . LEU C 1 3   ? 22.921  1.008   22.543  1.00 36.58  ? 3   LEU C CB  1 
ATOM   7174  C CG  . LEU C 1 3   ? 22.571  2.032   21.466  1.00 37.54  ? 3   LEU C CG  1 
ATOM   7175  C CD1 . LEU C 1 3   ? 23.783  2.882   21.084  1.00 36.41  ? 3   LEU C CD1 1 
ATOM   7176  C CD2 . LEU C 1 3   ? 22.003  1.310   20.249  1.00 36.76  ? 3   LEU C CD2 1 
ATOM   7177  N N   . LYS C 1 4   ? 21.564  2.615   24.852  1.00 34.38  ? 4   LYS C N   1 
ATOM   7178  C CA  . LYS C 1 4   ? 20.722  3.746   25.168  1.00 37.64  ? 4   LYS C CA  1 
ATOM   7179  C C   . LYS C 1 4   ? 21.309  4.495   26.375  1.00 37.48  ? 4   LYS C C   1 
ATOM   7180  O O   . LYS C 1 4   ? 21.231  5.718   26.437  1.00 39.82  ? 4   LYS C O   1 
ATOM   7181  C CB  . LYS C 1 4   ? 19.287  3.279   25.442  1.00 40.15  ? 4   LYS C CB  1 
ATOM   7182  C CG  . LYS C 1 4   ? 18.428  4.396   25.984  1.00 45.27  ? 4   LYS C CG  1 
ATOM   7183  C CD  . LYS C 1 4   ? 16.952  4.138   26.007  1.00 49.50  ? 4   LYS C CD  1 
ATOM   7184  C CE  . LYS C 1 4   ? 16.237  5.367   26.524  1.00 50.79  ? 4   LYS C CE  1 
ATOM   7185  N NZ  . LYS C 1 4   ? 14.852  5.445   26.001  1.00 55.77  ? 4   LYS C NZ  1 
ATOM   7186  N N   . GLU C 1 5   ? 21.894  3.762   27.322  1.00 41.89  ? 5   GLU C N   1 
ATOM   7187  C CA  . GLU C 1 5   ? 22.461  4.390   28.513  1.00 46.54  ? 5   GLU C CA  1 
ATOM   7188  C C   . GLU C 1 5   ? 23.616  5.287   28.092  1.00 46.52  ? 5   GLU C C   1 
ATOM   7189  O O   . GLU C 1 5   ? 23.767  6.401   28.578  1.00 41.98  ? 5   GLU C O   1 
ATOM   7190  C CB  . GLU C 1 5   ? 22.961  3.343   29.507  1.00 51.75  ? 5   GLU C CB  1 
ATOM   7191  C CG  . GLU C 1 5   ? 21.841  2.592   30.215  1.00 57.70  ? 5   GLU C CG  1 
ATOM   7192  C CD  . GLU C 1 5   ? 22.272  1.347   30.979  1.00 64.79  ? 5   GLU C CD  1 
ATOM   7193  O OE1 . GLU C 1 5   ? 21.429  0.783   31.700  1.00 69.78  ? 5   GLU C OE1 1 
ATOM   7194  O OE2 . GLU C 1 5   ? 23.440  0.926   30.841  1.00 69.14  ? 5   GLU C OE2 1 
ATOM   7195  N N   . ARG C 1 6   ? 24.391  4.811   27.117  1.00 41.40  ? 6   ARG C N   1 
ATOM   7196  C CA  . ARG C 1 6   ? 25.568  5.535   26.682  1.00 40.05  ? 6   ARG C CA  1 
ATOM   7197  C C   . ARG C 1 6   ? 25.132  6.804   25.963  1.00 40.52  ? 6   ARG C C   1 
ATOM   7198  O O   . ARG C 1 6   ? 25.645  7.892   26.223  1.00 35.68  ? 6   ARG C O   1 
ATOM   7199  C CB  . ARG C 1 6   ? 26.414  4.566   25.852  1.00 48.06  ? 6   ARG C CB  1 
ATOM   7200  C CG  . ARG C 1 6   ? 27.896  4.851   25.907  1.00 58.59  ? 6   ARG C CG  1 
ATOM   7201  C CD  . ARG C 1 6   ? 28.489  4.810   27.301  1.00 55.09  ? 6   ARG C CD  1 
ATOM   7202  N NE  . ARG C 1 6   ? 29.637  5.668   27.147  1.00 49.93  ? 6   ARG C NE  1 
ATOM   7203  C CZ  . ARG C 1 6   ? 29.751  6.875   27.653  1.00 53.64  ? 6   ARG C CZ  1 
ATOM   7204  N NH1 . ARG C 1 6   ? 29.011  7.231   28.685  1.00 65.49  ? 6   ARG C NH1 1 
ATOM   7205  N NH2 . ARG C 1 6   ? 30.650  7.695   27.152  1.00 49.10  ? 6   ARG C NH2 1 
ATOM   7206  N N   . LEU C 1 7   ? 24.113  6.691   25.101  1.00 39.35  ? 7   LEU C N   1 
ATOM   7207  C CA  . LEU C 1 7   ? 23.599  7.864   24.402  1.00 35.85  ? 7   LEU C CA  1 
ATOM   7208  C C   . LEU C 1 7   ? 22.981  8.835   25.401  1.00 32.15  ? 7   LEU C C   1 
ATOM   7209  O O   . LEU C 1 7   ? 22.999  10.041  25.187  1.00 34.81  ? 7   LEU C O   1 
ATOM   7210  C CB  . LEU C 1 7   ? 22.530  7.413   23.396  1.00 33.67  ? 7   LEU C CB  1 
ATOM   7211  C CG  . LEU C 1 7   ? 23.051  6.660   22.172  1.00 33.98  ? 7   LEU C CG  1 
ATOM   7212  C CD1 . LEU C 1 7   ? 21.887  6.194   21.283  1.00 37.00  ? 7   LEU C CD1 1 
ATOM   7213  C CD2 . LEU C 1 7   ? 24.032  7.537   21.398  1.00 33.22  ? 7   LEU C CD2 1 
ATOM   7214  N N   . ALA C 1 8   ? 22.389  8.303   26.474  1.00 36.84  ? 8   ALA C N   1 
ATOM   7215  C CA  . ALA C 1 8   ? 21.782  9.164   27.490  1.00 40.41  ? 8   ALA C CA  1 
ATOM   7216  C C   . ALA C 1 8   ? 22.850  10.062  28.124  1.00 36.66  ? 8   ALA C C   1 
ATOM   7217  O O   . ALA C 1 8   ? 22.586  11.221  28.403  1.00 42.93  ? 8   ALA C O   1 
ATOM   7218  C CB  . ALA C 1 8   ? 21.040  8.326   28.511  1.00 40.45  ? 8   ALA C CB  1 
ATOM   7219  N N   . GLU C 1 9   ? 24.093  9.587   28.222  1.00 39.50  ? 9   GLU C N   1 
ATOM   7220  C CA  . GLU C 1 9   ? 25.198  10.438  28.666  1.00 42.10  ? 9   GLU C CA  1 
ATOM   7221  C C   . GLU C 1 9   ? 25.754  11.304  27.538  1.00 42.32  ? 9   GLU C C   1 
ATOM   7222  O O   . GLU C 1 9   ? 26.009  12.484  27.710  1.00 39.50  ? 9   GLU C O   1 
ATOM   7223  C CB  . GLU C 1 9   ? 26.278  9.557   29.283  1.00 52.99  ? 9   GLU C CB  1 
ATOM   7224  C CG  . GLU C 1 9   ? 25.731  8.767   30.462  1.00 64.38  ? 9   GLU C CG  1 
ATOM   7225  C CD  . GLU C 1 9   ? 26.735  7.957   31.263  1.00 83.73  ? 9   GLU C CD  1 
ATOM   7226  O OE1 . GLU C 1 9   ? 26.856  6.736   30.990  1.00 88.56  ? 9   GLU C OE1 1 
ATOM   7227  O OE2 . GLU C 1 9   ? 27.362  8.540   32.183  1.00 96.37  ? 9   GLU C OE2 1 
ATOM   7228  N N   . LEU C 1 10  ? 25.923  10.743  26.343  1.00 45.95  ? 10  LEU C N   1 
ATOM   7229  C CA  . LEU C 1 10  ? 26.690  11.422  25.316  1.00 40.81  ? 10  LEU C CA  1 
ATOM   7230  C C   . LEU C 1 10  ? 25.878  12.529  24.675  1.00 36.79  ? 10  LEU C C   1 
ATOM   7231  O O   . LEU C 1 10  ? 26.382  13.611  24.431  1.00 37.04  ? 10  LEU C O   1 
ATOM   7232  C CB  . LEU C 1 10  ? 27.143  10.395  24.275  1.00 45.84  ? 10  LEU C CB  1 
ATOM   7233  C CG  . LEU C 1 10  ? 28.203  9.429   24.789  1.00 45.51  ? 10  LEU C CG  1 
ATOM   7234  C CD1 . LEU C 1 10  ? 28.370  8.252   23.834  1.00 46.38  ? 10  LEU C CD1 1 
ATOM   7235  C CD2 . LEU C 1 10  ? 29.514  10.169  24.987  1.00 44.56  ? 10  LEU C CD2 1 
ATOM   7236  N N   . ILE C 1 11  ? 24.621  12.268  24.347  1.00 38.40  ? 11  ILE C N   1 
ATOM   7237  C CA  . ILE C 1 11  ? 23.875  13.237  23.551  1.00 33.69  ? 11  ILE C CA  1 
ATOM   7238  C C   . ILE C 1 11  ? 23.731  14.609  24.221  1.00 31.37  ? 11  ILE C C   1 
ATOM   7239  O O   . ILE C 1 11  ? 23.748  15.635  23.538  1.00 32.07  ? 11  ILE C O   1 
ATOM   7240  C CB  . ILE C 1 11  ? 22.523  12.622  23.116  1.00 36.09  ? 11  ILE C CB  1 
ATOM   7241  C CG1 . ILE C 1 11  ? 22.743  11.659  21.945  1.00 38.22  ? 11  ILE C CG1 1 
ATOM   7242  C CG2 . ILE C 1 11  ? 21.502  13.696  22.764  1.00 33.53  ? 11  ILE C CG2 1 
ATOM   7243  C CD1 . ILE C 1 11  ? 21.528  10.905  21.558  1.00 42.13  ? 11  ILE C CD1 1 
ATOM   7244  N N   . PRO C 1 12  ? 23.452  14.734  25.537  1.00 38.35  ? 12  PRO C N   1 
ATOM   7245  C CA  . PRO C 1 12  ? 23.386  16.061  26.168  1.00 37.95  ? 12  PRO C CA  1 
ATOM   7246  C C   . PRO C 1 12  ? 24.686  16.855  26.018  1.00 35.17  ? 12  PRO C C   1 
ATOM   7247  O O   . PRO C 1 12  ? 24.679  18.051  25.725  1.00 43.61  ? 12  PRO C O   1 
ATOM   7248  C CB  . PRO C 1 12  ? 23.071  15.740  27.635  1.00 40.63  ? 12  PRO C CB  1 
ATOM   7249  C CG  . PRO C 1 12  ? 22.371  14.407  27.567  1.00 43.79  ? 12  PRO C CG  1 
ATOM   7250  C CD  . PRO C 1 12  ? 23.074  13.654  26.449  1.00 35.79  ? 12  PRO C CD  1 
ATOM   7251  N N   . GLN C 1 13  ? 25.809  16.162  26.123  1.00 40.79  ? 13  GLN C N   1 
ATOM   7252  C CA  . GLN C 1 13  ? 27.115  16.767  25.912  1.00 37.78  ? 13  GLN C CA  1 
ATOM   7253  C C   . GLN C 1 13  ? 27.293  17.231  24.477  1.00 40.52  ? 13  GLN C C   1 
ATOM   7254  O O   . GLN C 1 13  ? 27.745  18.347  24.244  1.00 34.93  ? 13  GLN C O   1 
ATOM   7255  C CB  . GLN C 1 13  ? 28.204  15.753  26.216  1.00 46.18  ? 13  GLN C CB  1 
ATOM   7256  C CG  . GLN C 1 13  ? 28.156  15.215  27.633  1.00 51.86  ? 13  GLN C CG  1 
ATOM   7257  C CD  . GLN C 1 13  ? 29.350  14.318  27.851  1.00 60.13  ? 13  GLN C CD  1 
ATOM   7258  O OE1 . GLN C 1 13  ? 30.415  14.531  27.280  1.00 68.04  ? 13  GLN C OE1 1 
ATOM   7259  N NE2 . GLN C 1 13  ? 29.177  13.285  28.652  1.00 60.39  ? 13  GLN C NE2 1 
ATOM   7260  N N   . TRP C 1 14  ? 26.975  16.353  23.504  1.00 40.77  ? 14  TRP C N   1 
ATOM   7261  C CA  . TRP C 1 14  ? 27.067  16.754  22.107  1.00 37.70  ? 14  TRP C CA  1 
ATOM   7262  C C   . TRP C 1 14  ? 26.150  17.932  21.827  1.00 33.27  ? 14  TRP C C   1 
ATOM   7263  O O   . TRP C 1 14  ? 26.511  18.883  21.139  1.00 34.02  ? 14  TRP C O   1 
ATOM   7264  C CB  . TRP C 1 14  ? 26.745  15.582  21.189  1.00 37.65  ? 14  TRP C CB  1 
ATOM   7265  C CG  . TRP C 1 14  ? 27.781  14.519  21.217  1.00 35.20  ? 14  TRP C CG  1 
ATOM   7266  C CD1 . TRP C 1 14  ? 29.091  14.651  21.567  1.00 36.69  ? 14  TRP C CD1 1 
ATOM   7267  C CD2 . TRP C 1 14  ? 27.574  13.125  20.933  1.00 40.35  ? 14  TRP C CD2 1 
ATOM   7268  N NE1 . TRP C 1 14  ? 29.709  13.428  21.532  1.00 38.87  ? 14  TRP C NE1 1 
ATOM   7269  C CE2 . TRP C 1 14  ? 28.813  12.478  21.117  1.00 35.72  ? 14  TRP C CE2 1 
ATOM   7270  C CE3 . TRP C 1 14  ? 26.467  12.369  20.532  1.00 37.80  ? 14  TRP C CE3 1 
ATOM   7271  C CZ2 . TRP C 1 14  ? 28.986  11.116  20.910  1.00 39.72  ? 14  TRP C CZ2 1 
ATOM   7272  C CZ3 . TRP C 1 14  ? 26.637  11.014  20.339  1.00 37.14  ? 14  TRP C CZ3 1 
ATOM   7273  C CH2 . TRP C 1 14  ? 27.878  10.399  20.513  1.00 39.70  ? 14  TRP C CH2 1 
ATOM   7274  N N   . ARG C 1 15  ? 24.937  17.871  22.371  1.00 37.97  ? 15  ARG C N   1 
ATOM   7275  C CA  . ARG C 1 15  ? 23.980  18.944  22.136  1.00 34.61  ? 15  ARG C CA  1 
ATOM   7276  C C   . ARG C 1 15  ? 24.573  20.294  22.566  1.00 36.50  ? 15  ARG C C   1 
ATOM   7277  O O   . ARG C 1 15  ? 24.372  21.308  21.887  1.00 35.75  ? 15  ARG C O   1 
ATOM   7278  C CB  . ARG C 1 15  ? 22.684  18.640  22.894  1.00 38.96  ? 15  ARG C CB  1 
ATOM   7279  C CG  . ARG C 1 15  ? 21.581  19.669  22.687  1.00 43.12  ? 15  ARG C CG  1 
ATOM   7280  C CD  . ARG C 1 15  ? 20.476  19.478  23.709  1.00 52.44  ? 15  ARG C CD  1 
ATOM   7281  N NE  . ARG C 1 15  ? 19.597  20.643  23.728  1.00 54.09  ? 15  ARG C NE  1 
ATOM   7282  C CZ  . ARG C 1 15  ? 18.751  20.938  24.712  1.00 59.74  ? 15  ARG C CZ  1 
ATOM   7283  N NH1 . ARG C 1 15  ? 18.774  20.250  25.839  1.00 65.24  ? 15  ARG C NH1 1 
ATOM   7284  N NH2 . ARG C 1 15  ? 17.899  21.940  24.579  1.00 61.74  ? 15  ARG C NH2 1 
ATOM   7285  N N   . ALA C 1 16  ? 25.209  20.299  23.743  1.00 34.05  ? 16  ALA C N   1 
ATOM   7286  C CA  . ALA C 1 16  ? 25.792  21.495  24.349  1.00 35.76  ? 16  ALA C CA  1 
ATOM   7287  C C   . ALA C 1 16  ? 26.961  21.983  23.507  1.00 35.57  ? 16  ALA C C   1 
ATOM   7288  O O   . ALA C 1 16  ? 27.050  23.176  23.251  1.00 40.35  ? 16  ALA C O   1 
ATOM   7289  C CB  . ALA C 1 16  ? 26.237  21.184  25.774  1.00 38.47  ? 16  ALA C CB  1 
ATOM   7290  N N   . GLU C 1 17  ? 27.807  21.047  23.026  1.00 38.11  ? 17  GLU C N   1 
ATOM   7291  C CA  . GLU C 1 17  ? 28.943  21.406  22.191  1.00 42.18  ? 17  GLU C CA  1 
ATOM   7292  C C   . GLU C 1 17  ? 28.461  21.990  20.876  1.00 42.41  ? 17  GLU C C   1 
ATOM   7293  O O   . GLU C 1 17  ? 29.009  22.992  20.421  1.00 41.16  ? 17  GLU C O   1 
ATOM   7294  C CB  . GLU C 1 17  ? 29.867  20.224  21.883  1.00 50.25  ? 17  GLU C CB  1 
ATOM   7295  C CG  . GLU C 1 17  ? 30.671  19.737  23.075  1.00 60.75  ? 17  GLU C CG  1 
ATOM   7296  C CD  . GLU C 1 17  ? 31.346  18.389  22.858  1.00 74.05  ? 17  GLU C CD  1 
ATOM   7297  O OE1 . GLU C 1 17  ? 31.964  18.211  21.781  1.00 79.65  ? 17  GLU C OE1 1 
ATOM   7298  O OE2 . GLU C 1 17  ? 31.255  17.516  23.759  1.00 76.79  ? 17  GLU C OE2 1 
ATOM   7299  N N   . VAL C 1 18  ? 27.447  21.360  20.257  1.00 39.91  ? 18  VAL C N   1 
ATOM   7300  C CA  . VAL C 1 18  ? 26.913  21.896  19.015  1.00 40.59  ? 18  VAL C CA  1 
ATOM   7301  C C   . VAL C 1 18  ? 26.371  23.296  19.264  1.00 37.92  ? 18  VAL C C   1 
ATOM   7302  O O   . VAL C 1 18  ? 26.546  24.162  18.419  1.00 41.31  ? 18  VAL C O   1 
ATOM   7303  C CB  . VAL C 1 18  ? 25.847  20.992  18.350  1.00 42.10  ? 18  VAL C CB  1 
ATOM   7304  C CG1 . VAL C 1 18  ? 24.989  21.749  17.348  1.00 43.61  ? 18  VAL C CG1 1 
ATOM   7305  C CG2 . VAL C 1 18  ? 26.487  19.790  17.681  1.00 43.15  ? 18  VAL C CG2 1 
ATOM   7306  N N   . ALA C 1 19  ? 25.648  23.504  20.373  1.00 42.91  ? 19  ALA C N   1 
ATOM   7307  C CA  . ALA C 1 19  ? 25.109  24.835  20.652  1.00 43.43  ? 19  ALA C CA  1 
ATOM   7308  C C   . ALA C 1 19  ? 26.241  25.881  20.710  1.00 39.45  ? 19  ALA C C   1 
ATOM   7309  O O   . ALA C 1 19  ? 26.098  26.966  20.156  1.00 34.98  ? 19  ALA C O   1 
ATOM   7310  C CB  . ALA C 1 19  ? 24.269  24.832  21.910  1.00 45.36  ? 19  ALA C CB  1 
ATOM   7311  N N   . GLU C 1 20  ? 27.381  25.538  21.315  1.00 42.88  ? 20  GLU C N   1 
ATOM   7312  C CA  . GLU C 1 20  ? 28.491  26.484  21.445  1.00 47.16  ? 20  GLU C CA  1 
ATOM   7313  C C   . GLU C 1 20  ? 29.131  26.747  20.081  1.00 45.75  ? 20  GLU C C   1 
ATOM   7314  O O   . GLU C 1 20  ? 29.475  27.885  19.730  1.00 39.78  ? 20  GLU C O   1 
ATOM   7315  C CB  . GLU C 1 20  ? 29.481  25.950  22.486  1.00 55.25  ? 20  GLU C CB  1 
ATOM   7316  C CG  . GLU C 1 20  ? 30.797  26.717  22.539  1.00 74.29  ? 20  GLU C CG  1 
ATOM   7317  C CD  . GLU C 1 20  ? 30.727  28.204  22.881  1.00 86.24  ? 20  GLU C CD  1 
ATOM   7318  O OE1 . GLU C 1 20  ? 29.612  28.722  23.158  1.00 85.98  ? 20  GLU C OE1 1 
ATOM   7319  O OE2 . GLU C 1 20  ? 31.798  28.853  22.871  1.00 93.94  ? 20  GLU C OE2 1 
ATOM   7320  N N   . ILE C 1 21  ? 29.252  25.694  19.261  1.00 46.12  ? 21  ILE C N   1 
ATOM   7321  C CA  . ILE C 1 21  ? 29.828  25.849  17.933  1.00 38.71  ? 21  ILE C CA  1 
ATOM   7322  C C   . ILE C 1 21  ? 29.016  26.826  17.097  1.00 40.71  ? 21  ILE C C   1 
ATOM   7323  O O   . ILE C 1 21  ? 29.585  27.634  16.383  1.00 42.21  ? 21  ILE C O   1 
ATOM   7324  C CB  . ILE C 1 21  ? 29.996  24.481  17.240  1.00 41.58  ? 21  ILE C CB  1 
ATOM   7325  C CG1 . ILE C 1 21  ? 31.201  23.740  17.811  1.00 45.33  ? 21  ILE C CG1 1 
ATOM   7326  C CG2 . ILE C 1 21  ? 30.084  24.627  15.729  1.00 42.34  ? 21  ILE C CG2 1 
ATOM   7327  C CD1 . ILE C 1 21  ? 31.237  22.273  17.478  1.00 51.08  ? 21  ILE C CD1 1 
ATOM   7328  N N   . ARG C 1 22  ? 27.686  26.715  17.100  1.00 43.16  ? 22  ARG C N   1 
ATOM   7329  C CA  . ARG C 1 22  ? 26.893  27.602  16.261  1.00 46.77  ? 22  ARG C CA  1 
ATOM   7330  C C   . ARG C 1 22  ? 26.993  29.041  16.779  1.00 45.83  ? 22  ARG C C   1 
ATOM   7331  O O   . ARG C 1 22  ? 27.008  29.979  15.999  1.00 49.45  ? 22  ARG C O   1 
ATOM   7332  C CB  . ARG C 1 22  ? 25.430  27.149  16.220  1.00 42.44  ? 22  ARG C CB  1 
ATOM   7333  C CG  . ARG C 1 22  ? 25.230  25.733  15.696  1.00 42.69  ? 22  ARG C CG  1 
ATOM   7334  C CD  . ARG C 1 22  ? 23.797  25.282  15.819  1.00 38.88  ? 22  ARG C CD  1 
ATOM   7335  N NE  . ARG C 1 22  ? 22.974  26.099  14.958  1.00 42.25  ? 22  ARG C NE  1 
ATOM   7336  C CZ  . ARG C 1 22  ? 21.661  26.154  15.006  1.00 40.38  ? 22  ARG C CZ  1 
ATOM   7337  N NH1 . ARG C 1 22  ? 21.004  25.481  15.933  1.00 48.69  ? 22  ARG C NH1 1 
ATOM   7338  N NH2 . ARG C 1 22  ? 21.018  26.915  14.141  1.00 40.86  ? 22  ARG C NH2 1 
ATOM   7339  N N   . LYS C 1 23  ? 27.011  29.206  18.104  1.00 46.62  ? 23  LYS C N   1 
ATOM   7340  C CA  . LYS C 1 23  ? 27.153  30.520  18.719  1.00 48.50  ? 23  LYS C CA  1 
ATOM   7341  C C   . LYS C 1 23  ? 28.496  31.151  18.333  1.00 49.49  ? 23  LYS C C   1 
ATOM   7342  O O   . LYS C 1 23  ? 28.544  32.216  17.722  1.00 47.37  ? 23  LYS C O   1 
ATOM   7343  C CB  . LYS C 1 23  ? 27.042  30.376  20.239  1.00 55.64  ? 23  LYS C CB  1 
ATOM   7344  C CG  . LYS C 1 23  ? 26.922  31.692  20.995  1.00 62.05  ? 23  LYS C CG  1 
ATOM   7345  C CD  . LYS C 1 23  ? 26.675  31.499  22.461  1.00 61.37  ? 23  LYS C CD  1 
ATOM   7346  C CE  . LYS C 1 23  ? 26.193  32.759  23.143  1.00 69.56  ? 23  LYS C CE  1 
ATOM   7347  N NZ  . LYS C 1 23  ? 26.064  32.543  24.601  1.00 74.19  ? 23  LYS C NZ  1 
ATOM   7348  N N   . LYS C 1 24  ? 29.589  30.447  18.634  1.00 49.56  ? 24  LYS C N   1 
ATOM   7349  C CA  . LYS C 1 24  ? 30.922  31.014  18.510  1.00 48.75  ? 24  LYS C CA  1 
ATOM   7350  C C   . LYS C 1 24  ? 31.399  31.017  17.059  1.00 48.49  ? 24  LYS C C   1 
ATOM   7351  O O   . LYS C 1 24  ? 32.053  31.968  16.644  1.00 49.32  ? 24  LYS C O   1 
ATOM   7352  C CB  . LYS C 1 24  ? 31.881  30.267  19.445  1.00 54.93  ? 24  LYS C CB  1 
ATOM   7353  C CG  . LYS C 1 24  ? 33.291  30.838  19.488  1.00 68.54  ? 24  LYS C CG  1 
ATOM   7354  C CD  . LYS C 1 24  ? 34.325  29.996  20.219  1.00 72.99  ? 24  LYS C CD  1 
ATOM   7355  C CE  . LYS C 1 24  ? 34.579  30.437  21.643  1.00 81.15  ? 24  LYS C CE  1 
ATOM   7356  N NZ  . LYS C 1 24  ? 35.867  29.902  22.146  1.00 78.58  ? 24  LYS C NZ  1 
ATOM   7357  N N   . TYR C 1 25  ? 31.060  29.995  16.252  1.00 44.97  ? 25  TYR C N   1 
ATOM   7358  C CA  . TYR C 1 25  ? 31.751  29.815  14.979  1.00 40.71  ? 25  TYR C CA  1 
ATOM   7359  C C   . TYR C 1 25  ? 30.850  29.905  13.760  1.00 40.90  ? 25  TYR C C   1 
ATOM   7360  O O   . TYR C 1 25  ? 31.329  29.675  12.658  1.00 45.94  ? 25  TYR C O   1 
ATOM   7361  C CB  . TYR C 1 25  ? 32.478  28.472  14.956  1.00 46.12  ? 25  TYR C CB  1 
ATOM   7362  C CG  . TYR C 1 25  ? 33.565  28.336  15.984  1.00 48.88  ? 25  TYR C CG  1 
ATOM   7363  C CD1 . TYR C 1 25  ? 34.615  29.245  16.026  1.00 53.53  ? 25  TYR C CD1 1 
ATOM   7364  C CD2 . TYR C 1 25  ? 33.578  27.276  16.878  1.00 55.62  ? 25  TYR C CD2 1 
ATOM   7365  C CE1 . TYR C 1 25  ? 35.638  29.114  16.953  1.00 61.26  ? 25  TYR C CE1 1 
ATOM   7366  C CE2 . TYR C 1 25  ? 34.601  27.127  17.805  1.00 59.86  ? 25  TYR C CE2 1 
ATOM   7367  C CZ  . TYR C 1 25  ? 35.627  28.052  17.841  1.00 60.44  ? 25  TYR C CZ  1 
ATOM   7368  O OH  . TYR C 1 25  ? 36.639  27.908  18.745  1.00 78.69  ? 25  TYR C OH  1 
ATOM   7369  N N   . GLY C 1 26  ? 29.582  30.281  13.946  1.00 44.02  ? 26  GLY C N   1 
ATOM   7370  C CA  . GLY C 1 26  ? 28.613  30.333  12.867  1.00 43.11  ? 26  GLY C CA  1 
ATOM   7371  C C   . GLY C 1 26  ? 29.075  31.218  11.719  1.00 49.23  ? 26  GLY C C   1 
ATOM   7372  O O   . GLY C 1 26  ? 28.710  30.997  10.558  1.00 41.03  ? 26  GLY C O   1 
ATOM   7373  N N   . ASN C 1 27  ? 29.883  32.234  12.057  1.00 40.02  ? 27  ASN C N   1 
ATOM   7374  C CA  . ASN C 1 27  ? 30.201  33.257  11.086  1.00 45.45  ? 27  ASN C CA  1 
ATOM   7375  C C   . ASN C 1 27  ? 31.509  32.937  10.377  1.00 38.36  ? 27  ASN C C   1 
ATOM   7376  O O   . ASN C 1 27  ? 31.924  33.724  9.533   1.00 44.26  ? 27  ASN C O   1 
ATOM   7377  C CB  . ASN C 1 27  ? 30.273  34.655  11.709  1.00 57.57  ? 27  ASN C CB  1 
ATOM   7378  C CG  . ASN C 1 27  ? 31.411  34.851  12.690  1.00 57.45  ? 27  ASN C CG  1 
ATOM   7379  O OD1 . ASN C 1 27  ? 32.198  33.940  12.982  1.00 54.05  ? 27  ASN C OD1 1 
ATOM   7380  N ND2 . ASN C 1 27  ? 31.497  36.062  13.216  1.00 68.58  ? 27  ASN C ND2 1 
ATOM   7381  N N   . ARG C 1 28  ? 32.135  31.802  10.711  1.00 42.23  ? 28  ARG C N   1 
ATOM   7382  C CA  . ARG C 1 28  ? 33.373  31.406  10.049  1.00 43.38  ? 28  ARG C CA  1 
ATOM   7383  C C   . ARG C 1 28  ? 33.112  30.891  8.625   1.00 48.69  ? 28  ARG C C   1 
ATOM   7384  O O   . ARG C 1 28  ? 32.175  30.130  8.347   1.00 43.59  ? 28  ARG C O   1 
ATOM   7385  C CB  . ARG C 1 28  ? 34.095  30.358  10.892  1.00 41.68  ? 28  ARG C CB  1 
ATOM   7386  C CG  . ARG C 1 28  ? 34.576  30.858  12.241  1.00 45.97  ? 28  ARG C CG  1 
ATOM   7387  C CD  . ARG C 1 28  ? 35.456  32.104  12.143  1.00 49.87  ? 28  ARG C CD  1 
ATOM   7388  N NE  . ARG C 1 28  ? 36.342  32.237  13.298  1.00 50.92  ? 28  ARG C NE  1 
ATOM   7389  C CZ  . ARG C 1 28  ? 35.996  32.728  14.491  1.00 55.79  ? 28  ARG C CZ  1 
ATOM   7390  N NH1 . ARG C 1 28  ? 34.800  33.254  14.689  1.00 54.25  ? 28  ARG C NH1 1 
ATOM   7391  N NH2 . ARG C 1 28  ? 36.864  32.717  15.489  1.00 59.99  ? 28  ARG C NH2 1 
ATOM   7392  N N   . LYS C 1 29  ? 33.977  31.307  7.703   1.00 43.19  ? 29  LYS C N   1 
ATOM   7393  C CA  . LYS C 1 29  ? 33.816  30.953  6.309   1.00 43.32  ? 29  LYS C CA  1 
ATOM   7394  C C   . LYS C 1 29  ? 34.559  29.645  6.031   1.00 45.50  ? 29  LYS C C   1 
ATOM   7395  O O   . LYS C 1 29  ? 35.660  29.424  6.530   1.00 38.94  ? 29  LYS C O   1 
ATOM   7396  C CB  . LYS C 1 29  ? 34.300  32.106  5.439   1.00 46.73  ? 29  LYS C CB  1 
ATOM   7397  C CG  . LYS C 1 29  ? 34.381  31.787  3.957   1.00 50.17  ? 29  LYS C CG  1 
ATOM   7398  C CD  . LYS C 1 29  ? 35.023  32.875  3.151   1.00 49.94  ? 29  LYS C CD  1 
ATOM   7399  C CE  . LYS C 1 29  ? 35.326  32.367  1.765   1.00 53.71  ? 29  LYS C CE  1 
ATOM   7400  N NZ  . LYS C 1 29  ? 35.673  33.471  0.852   1.00 60.42  ? 29  LYS C NZ  1 
ATOM   7401  N N   . THR C 1 30  ? 33.926  28.747  5.267   1.00 44.18  ? 30  THR C N   1 
ATOM   7402  C CA  . THR C 1 30  ? 34.606  27.514  4.900   1.00 38.10  ? 30  THR C CA  1 
ATOM   7403  C C   . THR C 1 30  ? 34.972  27.574  3.434   1.00 34.60  ? 30  THR C C   1 
ATOM   7404  O O   . THR C 1 30  ? 35.915  26.905  3.056   1.00 44.12  ? 30  THR C O   1 
ATOM   7405  C CB  . THR C 1 30  ? 33.791  26.235  5.142   1.00 41.12  ? 30  THR C CB  1 
ATOM   7406  O OG1 . THR C 1 30  ? 32.533  26.409  4.491   1.00 35.73  ? 30  THR C OG1 1 
ATOM   7407  C CG2 . THR C 1 30  ? 33.640  25.922  6.605   1.00 39.61  ? 30  THR C CG2 1 
ATOM   7408  N N   . MET C 1 31  ? 34.219  28.314  2.604   1.00 33.73  ? 31  MET C N   1 
ATOM   7409  C CA  . MET C 1 31  ? 34.539  28.312  1.192   1.00 37.14  ? 31  MET C CA  1 
ATOM   7410  C C   . MET C 1 31  ? 33.607  29.306  0.551   1.00 39.03  ? 31  MET C C   1 
ATOM   7411  O O   . MET C 1 31  ? 32.693  29.768  1.227   1.00 37.08  ? 31  MET C O   1 
ATOM   7412  C CB  . MET C 1 31  ? 34.366  26.902  0.583   1.00 41.69  ? 31  MET C CB  1 
ATOM   7413  C CG  . MET C 1 31  ? 33.048  26.200  0.988   1.00 49.51  ? 31  MET C CG  1 
ATOM   7414  S SD  . MET C 1 31  ? 32.689  24.562  0.204   1.00 41.85  ? 31  MET C SD  1 
ATOM   7415  C CE  . MET C 1 31  ? 32.943  24.949  -1.517  1.00 38.19  ? 31  MET C CE  1 
ATOM   7416  N N   . ASP C 1 32  ? 33.806  29.571  -0.743  1.00 39.32  ? 32  ASP C N   1 
ATOM   7417  C CA  . ASP C 1 32  ? 32.876  30.368  -1.515  1.00 42.57  ? 32  ASP C CA  1 
ATOM   7418  C C   . ASP C 1 32  ? 31.719  29.495  -2.026  1.00 47.43  ? 32  ASP C C   1 
ATOM   7419  O O   . ASP C 1 32  ? 31.902  28.344  -2.404  1.00 42.89  ? 32  ASP C O   1 
ATOM   7420  C CB  . ASP C 1 32  ? 33.587  31.033  -2.696  1.00 48.11  ? 32  ASP C CB  1 
ATOM   7421  C CG  . ASP C 1 32  ? 34.686  32.040  -2.322  1.00 59.51  ? 32  ASP C CG  1 
ATOM   7422  O OD1 . ASP C 1 32  ? 34.758  32.454  -1.143  1.00 52.07  ? 32  ASP C OD1 1 
ATOM   7423  O OD2 . ASP C 1 32  ? 35.484  32.400  -3.210  1.00 55.07  ? 32  ASP C OD2 1 
ATOM   7424  N N   . CYS C 1 33  ? 30.529  30.091  -2.104  1.00 43.17  ? 33  CYS C N   1 
ATOM   7425  C CA  . CYS C 1 33  ? 29.396  29.502  -2.782  1.00 42.95  ? 33  CYS C CA  1 
ATOM   7426  C C   . CYS C 1 33  ? 29.299  30.130  -4.160  1.00 38.24  ? 33  CYS C C   1 
ATOM   7427  O O   . CYS C 1 33  ? 29.395  31.340  -4.309  1.00 43.92  ? 33  CYS C O   1 
ATOM   7428  C CB  . CYS C 1 33  ? 28.121  29.711  -1.964  1.00 44.08  ? 33  CYS C CB  1 
ATOM   7429  S SG  . CYS C 1 33  ? 26.642  28.988  -2.729  1.00 43.66  ? 33  CYS C SG  1 
ATOM   7430  N N   . THR C 1 34  ? 29.106  29.315  -5.189  1.00 38.85  ? 34  THR C N   1 
ATOM   7431  C CA  . THR C 1 34  ? 29.191  29.829  -6.545  1.00 35.63  ? 34  THR C CA  1 
ATOM   7432  C C   . THR C 1 34  ? 27.938  29.542  -7.357  1.00 39.23  ? 34  THR C C   1 
ATOM   7433  O O   . THR C 1 34  ? 27.105  28.714  -7.004  1.00 38.49  ? 34  THR C O   1 
ATOM   7434  C CB  . THR C 1 34  ? 30.379  29.205  -7.299  1.00 40.36  ? 34  THR C CB  1 
ATOM   7435  O OG1 . THR C 1 34  ? 30.100  27.820  -7.515  1.00 36.31  ? 34  THR C OG1 1 
ATOM   7436  C CG2 . THR C 1 34  ? 31.701  29.379  -6.575  1.00 37.58  ? 34  THR C CG2 1 
ATOM   7437  N N   . ILE C 1 35  ? 27.856  30.204  -8.507  1.00 38.23  ? 35  ILE C N   1 
ATOM   7438  C CA  . ILE C 1 35  ? 26.854  29.900  -9.501  1.00 38.14  ? 35  ILE C CA  1 
ATOM   7439  C C   . ILE C 1 35  ? 26.938  28.436  -9.936  1.00 41.82  ? 35  ILE C C   1 
ATOM   7440  O O   . ILE C 1 35  ? 25.910  27.822  -10.187 1.00 42.85  ? 35  ILE C O   1 
ATOM   7441  C CB  . ILE C 1 35  ? 26.987  30.872  -10.680 1.00 37.54  ? 35  ILE C CB  1 
ATOM   7442  C CG1 . ILE C 1 35  ? 26.580  32.282  -10.235 1.00 41.83  ? 35  ILE C CG1 1 
ATOM   7443  C CG2 . ILE C 1 35  ? 26.176  30.368  -11.864 1.00 39.31  ? 35  ILE C CG2 1 
ATOM   7444  C CD1 . ILE C 1 35  ? 26.291  33.212  -11.359 1.00 54.11  ? 35  ILE C CD1 1 
ATOM   7445  N N   . GLY C 1 36  ? 28.150  27.898  -10.059 1.00 40.20  ? 36  GLY C N   1 
ATOM   7446  C CA  . GLY C 1 36  ? 28.363  26.505  -10.432 1.00 41.41  ? 36  GLY C CA  1 
ATOM   7447  C C   . GLY C 1 36  ? 27.791  25.524  -9.401  1.00 40.23  ? 36  GLY C C   1 
ATOM   7448  O O   . GLY C 1 36  ? 27.337  24.449  -9.760  1.00 40.69  ? 36  GLY C O   1 
ATOM   7449  N N   . HIS C 1 37  ? 27.840  25.898  -8.121  1.00 36.05  ? 37  HIS C N   1 
ATOM   7450  C CA  . HIS C 1 37  ? 27.185  25.162  -7.055  1.00 37.72  ? 37  HIS C CA  1 
ATOM   7451  C C   . HIS C 1 37  ? 25.686  25.025  -7.304  1.00 38.62  ? 37  HIS C C   1 
ATOM   7452  O O   . HIS C 1 37  ? 25.158  23.910  -7.267  1.00 38.14  ? 37  HIS C O   1 
ATOM   7453  C CB  . HIS C 1 37  ? 27.493  25.794  -5.712  1.00 36.36  ? 37  HIS C CB  1 
ATOM   7454  C CG  . HIS C 1 37  ? 28.899  25.529  -5.291  1.00 40.54  ? 37  HIS C CG  1 
ATOM   7455  N ND1 . HIS C 1 37  ? 29.713  26.504  -4.765  1.00 38.20  ? 37  HIS C ND1 1 
ATOM   7456  C CD2 . HIS C 1 37  ? 29.626  24.405  -5.297  1.00 40.39  ? 37  HIS C CD2 1 
ATOM   7457  C CE1 . HIS C 1 37  ? 30.895  25.964  -4.457  1.00 43.48  ? 37  HIS C CE1 1 
ATOM   7458  N NE2 . HIS C 1 37  ? 30.866  24.695  -4.769  1.00 38.96  ? 37  HIS C NE2 1 
ATOM   7459  N N   . ALA C 1 38  ? 25.031  26.135  -7.646  1.00 35.59  ? 38  ALA C N   1 
ATOM   7460  C CA  . ALA C 1 38  ? 23.594  26.151  -7.802  1.00 37.72  ? 38  ALA C CA  1 
ATOM   7461  C C   . ALA C 1 38  ? 23.165  25.300  -8.993  1.00 44.53  ? 38  ALA C C   1 
ATOM   7462  O O   . ALA C 1 38  ? 22.186  24.543  -8.868  1.00 43.45  ? 38  ALA C O   1 
ATOM   7463  C CB  . ALA C 1 38  ? 23.082  27.564  -7.899  1.00 38.02  ? 38  ALA C CB  1 
ATOM   7464  N N   . TYR C 1 39  ? 23.865  25.436  -10.133 1.00 37.94  ? 39  TYR C N   1 
ATOM   7465  C CA  . TYR C 1 39  ? 23.534  24.667  -11.330 1.00 38.24  ? 39  TYR C CA  1 
ATOM   7466  C C   . TYR C 1 39  ? 24.256  23.314  -11.409 1.00 37.24  ? 39  TYR C C   1 
ATOM   7467  O O   . TYR C 1 39  ? 24.103  22.589  -12.385 1.00 49.97  ? 39  TYR C O   1 
ATOM   7468  C CB  . TYR C 1 39  ? 23.865  25.455  -12.596 1.00 34.69  ? 39  TYR C CB  1 
ATOM   7469  C CG  . TYR C 1 39  ? 22.951  26.619  -12.853 1.00 35.95  ? 39  TYR C CG  1 
ATOM   7470  C CD1 . TYR C 1 39  ? 23.168  27.830  -12.225 1.00 38.38  ? 39  TYR C CD1 1 
ATOM   7471  C CD2 . TYR C 1 39  ? 21.878  26.514  -13.712 1.00 35.07  ? 39  TYR C CD2 1 
ATOM   7472  C CE1 . TYR C 1 39  ? 22.334  28.906  -12.439 1.00 41.88  ? 39  TYR C CE1 1 
ATOM   7473  C CE2 . TYR C 1 39  ? 21.027  27.582  -13.941 1.00 40.53  ? 39  TYR C CE2 1 
ATOM   7474  C CZ  . TYR C 1 39  ? 21.268  28.792  -13.303 1.00 42.01  ? 39  TYR C CZ  1 
ATOM   7475  O OH  . TYR C 1 39  ? 20.451  29.869  -13.503 1.00 44.44  ? 39  TYR C OH  1 
ATOM   7476  N N   . GLY C 1 40  ? 25.089  22.981  -10.431 1.00 37.51  ? 40  GLY C N   1 
ATOM   7477  C CA  . GLY C 1 40  ? 25.931  21.799  -10.512 1.00 37.84  ? 40  GLY C CA  1 
ATOM   7478  C C   . GLY C 1 40  ? 25.647  20.828  -9.373  1.00 35.95  ? 40  GLY C C   1 
ATOM   7479  O O   . GLY C 1 40  ? 26.513  20.036  -8.998  1.00 35.82  ? 40  GLY C O   1 
ATOM   7480  N N   . GLY C 1 41  ? 24.433  20.908  -8.805  1.00 38.42  ? 41  GLY C N   1 
ATOM   7481  C CA  . GLY C 1 41  ? 24.046  20.005  -7.728  1.00 34.09  ? 41  GLY C CA  1 
ATOM   7482  C C   . GLY C 1 41  ? 24.886  20.150  -6.466  1.00 33.52  ? 41  GLY C C   1 
ATOM   7483  O O   . GLY C 1 41  ? 25.109  19.176  -5.762  1.00 34.63  ? 41  GLY C O   1 
ATOM   7484  N N   . MET C 1 42  ? 25.363  21.362  -6.164  1.00 33.11  ? 42  MET C N   1 
ATOM   7485  C CA  . MET C 1 42  ? 26.060  21.627  -4.911  1.00 31.17  ? 42  MET C CA  1 
ATOM   7486  C C   . MET C 1 42  ? 27.367  20.858  -4.766  1.00 29.35  ? 42  MET C C   1 
ATOM   7487  O O   . MET C 1 42  ? 27.835  20.611  -3.650  1.00 32.99  ? 42  MET C O   1 
ATOM   7488  C CB  . MET C 1 42  ? 25.214  21.263  -3.688  1.00 37.22  ? 42  MET C CB  1 
ATOM   7489  C CG  . MET C 1 42  ? 23.843  21.863  -3.649  1.00 41.07  ? 42  MET C CG  1 
ATOM   7490  S SD  . MET C 1 42  ? 23.066  21.620  -2.007  1.00 43.55  ? 42  MET C SD  1 
ATOM   7491  C CE  . MET C 1 42  ? 21.359  21.829  -2.494  1.00 48.84  ? 42  MET C CE  1 
ATOM   7492  N N   . ARG C 1 43  ? 27.961  20.409  -5.862  1.00 31.83  ? 43  ARG C N   1 
ATOM   7493  C CA  . ARG C 1 43  ? 29.164  19.600  -5.766  1.00 35.30  ? 43  ARG C CA  1 
ATOM   7494  C C   . ARG C 1 43  ? 30.282  20.323  -4.988  1.00 36.09  ? 43  ARG C C   1 
ATOM   7495  O O   . ARG C 1 43  ? 30.680  21.431  -5.301  1.00 37.31  ? 43  ARG C O   1 
ATOM   7496  C CB  . ARG C 1 43  ? 29.594  19.227  -7.183  1.00 41.99  ? 43  ARG C CB  1 
ATOM   7497  C CG  . ARG C 1 43  ? 30.898  18.447  -7.238  1.00 51.85  ? 43  ARG C CG  1 
ATOM   7498  C CD  . ARG C 1 43  ? 31.623  18.655  -8.565  1.00 56.66  ? 43  ARG C CD  1 
ATOM   7499  N NE  . ARG C 1 43  ? 31.145  17.746  -9.589  1.00 58.32  ? 43  ARG C NE  1 
ATOM   7500  C CZ  . ARG C 1 43  ? 31.520  16.471  -9.710  1.00 60.65  ? 43  ARG C CZ  1 
ATOM   7501  N NH1 . ARG C 1 43  ? 32.513  15.982  -8.989  1.00 55.28  ? 43  ARG C NH1 1 
ATOM   7502  N NH2 . ARG C 1 43  ? 30.927  15.700  -10.602 1.00 54.43  ? 43  ARG C NH2 1 
ATOM   7503  N N   . GLY C 1 44  ? 30.812  19.682  -3.952  1.00 35.31  ? 44  GLY C N   1 
ATOM   7504  C CA  . GLY C 1 44  ? 31.803  20.311  -3.093  1.00 40.46  ? 44  GLY C CA  1 
ATOM   7505  C C   . GLY C 1 44  ? 31.227  21.278  -2.050  1.00 39.46  ? 44  GLY C C   1 
ATOM   7506  O O   . GLY C 1 44  ? 31.962  21.750  -1.190  1.00 36.85  ? 44  GLY C O   1 
ATOM   7507  N N   . LEU C 1 45  ? 29.941  21.643  -2.116  1.00 38.75  ? 45  LEU C N   1 
ATOM   7508  C CA  . LEU C 1 45  ? 29.478  22.690  -1.206  1.00 36.56  ? 45  LEU C CA  1 
ATOM   7509  C C   . LEU C 1 45  ? 29.360  22.117  0.201   1.00 39.68  ? 45  LEU C C   1 
ATOM   7510  O O   . LEU C 1 45  ? 28.685  21.109  0.399   1.00 38.25  ? 45  LEU C O   1 
ATOM   7511  C CB  . LEU C 1 45  ? 28.171  23.264  -1.726  1.00 34.53  ? 45  LEU C CB  1 
ATOM   7512  C CG  . LEU C 1 45  ? 27.611  24.485  -0.988  1.00 40.72  ? 45  LEU C CG  1 
ATOM   7513  C CD1 . LEU C 1 45  ? 28.592  25.651  -1.003  1.00 42.30  ? 45  LEU C CD1 1 
ATOM   7514  C CD2 . LEU C 1 45  ? 26.301  24.910  -1.616  1.00 40.62  ? 45  LEU C CD2 1 
ATOM   7515  N N   . LYS C 1 46  ? 30.042  22.728  1.179   1.00 37.37  ? 46  LYS C N   1 
ATOM   7516  C CA  . LYS C 1 46  ? 30.084  22.182  2.527   1.00 36.71  ? 46  LYS C CA  1 
ATOM   7517  C C   . LYS C 1 46  ? 28.824  22.572  3.312   1.00 40.61  ? 46  LYS C C   1 
ATOM   7518  O O   . LYS C 1 46  ? 28.852  23.443  4.178   1.00 40.28  ? 46  LYS C O   1 
ATOM   7519  C CB  . LYS C 1 46  ? 31.351  22.655  3.240   1.00 40.52  ? 46  LYS C CB  1 
ATOM   7520  C CG  . LYS C 1 46  ? 32.643  21.939  2.834   1.00 42.12  ? 46  LYS C CG  1 
ATOM   7521  C CD  . LYS C 1 46  ? 33.854  22.542  3.531   1.00 44.11  ? 46  LYS C CD  1 
ATOM   7522  C CE  . LYS C 1 46  ? 35.128  21.723  3.466   1.00 49.44  ? 46  LYS C CE  1 
ATOM   7523  N NZ  . LYS C 1 46  ? 35.597  21.591  2.079   1.00 54.47  ? 46  LYS C NZ  1 
ATOM   7524  N N   . ALA C 1 47  ? 27.709  21.865  3.072   1.00 38.24  ? 47  ALA C N   1 
ATOM   7525  C CA  . ALA C 1 47  ? 26.399  22.386  3.429   1.00 35.73  ? 47  ALA C CA  1 
ATOM   7526  C C   . ALA C 1 47  ? 25.649  21.550  4.470   1.00 37.84  ? 47  ALA C C   1 
ATOM   7527  O O   . ALA C 1 47  ? 24.520  21.916  4.801   1.00 41.05  ? 47  ALA C O   1 
ATOM   7528  C CB  . ALA C 1 47  ? 25.618  22.526  2.153   1.00 38.77  ? 47  ALA C CB  1 
ATOM   7529  N N   . LEU C 1 48  ? 26.246  20.458  4.969   1.00 33.85  ? 48  LEU C N   1 
ATOM   7530  C CA  . LEU C 1 48  ? 25.576  19.505  5.843   1.00 33.63  ? 48  LEU C CA  1 
ATOM   7531  C C   . LEU C 1 48  ? 26.555  19.071  6.906   1.00 31.40  ? 48  LEU C C   1 
ATOM   7532  O O   . LEU C 1 48  ? 27.738  19.059  6.645   1.00 33.52  ? 48  LEU C O   1 
ATOM   7533  C CB  . LEU C 1 48  ? 25.185  18.222  5.084   1.00 38.24  ? 48  LEU C CB  1 
ATOM   7534  C CG  . LEU C 1 48  ? 24.119  18.342  4.009   1.00 48.87  ? 48  LEU C CG  1 
ATOM   7535  C CD1 . LEU C 1 48  ? 23.943  17.008  3.306   1.00 51.14  ? 48  LEU C CD1 1 
ATOM   7536  C CD2 . LEU C 1 48  ? 22.794  18.816  4.605   1.00 50.90  ? 48  LEU C CD2 1 
ATOM   7537  N N   . VAL C 1 49  ? 26.027  18.567  8.019   1.00 34.46  ? 49  VAL C N   1 
ATOM   7538  C CA  . VAL C 1 49  ? 26.811  17.938  9.055   1.00 36.84  ? 49  VAL C CA  1 
ATOM   7539  C C   . VAL C 1 49  ? 26.529  16.442  9.106   1.00 38.02  ? 49  VAL C C   1 
ATOM   7540  O O   . VAL C 1 49  ? 25.378  16.028  9.091   1.00 37.11  ? 49  VAL C O   1 
ATOM   7541  C CB  . VAL C 1 49  ? 26.510  18.585  10.415  1.00 40.94  ? 49  VAL C CB  1 
ATOM   7542  C CG1 . VAL C 1 49  ? 27.188  17.826  11.541  1.00 42.55  ? 49  VAL C CG1 1 
ATOM   7543  C CG2 . VAL C 1 49  ? 26.945  20.044  10.408  1.00 44.45  ? 49  VAL C CG2 1 
ATOM   7544  N N   . CYS C 1 50  ? 27.596  15.649  9.262   1.00 35.69  ? 50  CYS C N   1 
ATOM   7545  C CA  . CYS C 1 50  ? 27.471  14.214  9.492   1.00 37.29  ? 50  CYS C CA  1 
ATOM   7546  C C   . CYS C 1 50  ? 28.642  13.722  10.331  1.00 34.19  ? 50  CYS C C   1 
ATOM   7547  O O   . CYS C 1 50  ? 29.794  13.858  9.915   1.00 38.80  ? 50  CYS C O   1 
ATOM   7548  C CB  . CYS C 1 50  ? 27.412  13.467  8.159   1.00 35.30  ? 50  CYS C CB  1 
ATOM   7549  S SG  . CYS C 1 50  ? 27.445  11.662  8.330   1.00 40.46  ? 50  CYS C SG  1 
ATOM   7550  N N   . ASP C 1 51  ? 28.348  13.130  11.495  1.00 31.10  ? 51  ASP C N   1 
ATOM   7551  C CA  . ASP C 1 51  ? 29.371  12.685  12.428  1.00 32.20  ? 51  ASP C CA  1 
ATOM   7552  C C   . ASP C 1 51  ? 29.564  11.177  12.372  1.00 33.09  ? 51  ASP C C   1 
ATOM   7553  O O   . ASP C 1 51  ? 30.471  10.652  12.982  1.00 34.50  ? 51  ASP C O   1 
ATOM   7554  C CB  . ASP C 1 51  ? 29.074  13.171  13.847  1.00 36.07  ? 51  ASP C CB  1 
ATOM   7555  C CG  . ASP C 1 51  ? 29.450  14.641  13.997  1.00 43.13  ? 51  ASP C CG  1 
ATOM   7556  O OD1 . ASP C 1 51  ? 30.545  15.014  13.492  1.00 38.39  ? 51  ASP C OD1 1 
ATOM   7557  O OD2 . ASP C 1 51  ? 28.611  15.423  14.486  1.00 43.33  ? 51  ASP C OD2 1 
ATOM   7558  N N   . THR C 1 52  ? 28.698  10.453  11.672  1.00 29.99  ? 52  THR C N   1 
ATOM   7559  C CA  . THR C 1 52  ? 28.792  9.007   11.699  1.00 28.96  ? 52  THR C CA  1 
ATOM   7560  C C   . THR C 1 52  ? 29.976  8.528   10.862  1.00 30.50  ? 52  THR C C   1 
ATOM   7561  O O   . THR C 1 52  ? 30.617  7.544   11.207  1.00 31.32  ? 52  THR C O   1 
ATOM   7562  C CB  . THR C 1 52  ? 27.502  8.357   11.193  1.00 30.48  ? 52  THR C CB  1 
ATOM   7563  O OG1 . THR C 1 52  ? 27.187  8.857   9.893   1.00 29.87  ? 52  THR C OG1 1 
ATOM   7564  C CG2 . THR C 1 52  ? 26.340  8.657   12.116  1.00 33.03  ? 52  THR C CG2 1 
ATOM   7565  N N   . SER C 1 53  ? 30.176  9.157   9.703   1.00 32.72  ? 53  SER C N   1 
ATOM   7566  C CA  . SER C 1 53  ? 31.221  8.725   8.798   1.00 34.20  ? 53  SER C CA  1 
ATOM   7567  C C   . SER C 1 53  ? 31.737  9.925   8.019   1.00 32.76  ? 53  SER C C   1 
ATOM   7568  O O   . SER C 1 53  ? 31.083  10.951  7.908   1.00 35.11  ? 53  SER C O   1 
ATOM   7569  C CB  . SER C 1 53  ? 30.708  7.643   7.864   1.00 36.03  ? 53  SER C CB  1 
ATOM   7570  O OG  . SER C 1 53  ? 29.764  8.200   6.952   1.00 33.30  ? 53  SER C OG  1 
ATOM   7571  N N   . GLU C 1 54  ? 32.907  9.748   7.423   1.00 32.90  ? 54  GLU C N   1 
ATOM   7572  C CA  . GLU C 1 54  ? 33.523  10.802  6.645   1.00 32.67  ? 54  GLU C CA  1 
ATOM   7573  C C   . GLU C 1 54  ? 34.340  10.140  5.553   1.00 30.20  ? 54  GLU C C   1 
ATOM   7574  O O   . GLU C 1 54  ? 35.105  9.223   5.843   1.00 32.32  ? 54  GLU C O   1 
ATOM   7575  C CB  . GLU C 1 54  ? 34.423  11.600  7.599   1.00 35.85  ? 54  GLU C CB  1 
ATOM   7576  C CG  . GLU C 1 54  ? 35.303  12.651  6.967   1.00 39.59  ? 54  GLU C CG  1 
ATOM   7577  C CD  . GLU C 1 54  ? 36.078  13.461  8.008   1.00 42.69  ? 54  GLU C CD  1 
ATOM   7578  O OE1 . GLU C 1 54  ? 36.407  14.589  7.694   1.00 47.19  ? 54  GLU C OE1 1 
ATOM   7579  O OE2 . GLU C 1 54  ? 36.361  12.943  9.133   1.00 38.11  ? 54  GLU C OE2 1 
ATOM   7580  N N   . VAL C 1 55  ? 34.249  10.686  4.344   1.00 33.11  ? 55  VAL C N   1 
ATOM   7581  C CA  . VAL C 1 55  ? 34.908  10.122  3.181   1.00 37.96  ? 55  VAL C CA  1 
ATOM   7582  C C   . VAL C 1 55  ? 36.085  11.022  2.799   1.00 45.16  ? 55  VAL C C   1 
ATOM   7583  O O   . VAL C 1 55  ? 35.880  12.157  2.393   1.00 43.50  ? 55  VAL C O   1 
ATOM   7584  C CB  . VAL C 1 55  ? 33.929  10.000  1.996   1.00 41.48  ? 55  VAL C CB  1 
ATOM   7585  C CG1 . VAL C 1 55  ? 34.622  9.437   0.764   1.00 43.38  ? 55  VAL C CG1 1 
ATOM   7586  C CG2 . VAL C 1 55  ? 32.693  9.182   2.334   1.00 40.08  ? 55  VAL C CG2 1 
ATOM   7587  N N   . PHE C 1 56  ? 37.297  10.472  2.907   1.00 45.79  ? 56  PHE C N   1 
ATOM   7588  C CA  . PHE C 1 56  ? 38.543  11.138  2.580   1.00 49.18  ? 56  PHE C CA  1 
ATOM   7589  C C   . PHE C 1 56  ? 38.928  10.812  1.134   1.00 52.04  ? 56  PHE C C   1 
ATOM   7590  O O   . PHE C 1 56  ? 39.008  9.639   0.773   1.00 49.80  ? 56  PHE C O   1 
ATOM   7591  C CB  . PHE C 1 56  ? 39.641  10.648  3.523   1.00 42.34  ? 56  PHE C CB  1 
ATOM   7592  C CG  . PHE C 1 56  ? 39.473  11.028  4.969   1.00 45.49  ? 56  PHE C CG  1 
ATOM   7593  C CD1 . PHE C 1 56  ? 38.641  10.304  5.816   1.00 44.27  ? 56  PHE C CD1 1 
ATOM   7594  C CD2 . PHE C 1 56  ? 40.123  12.135  5.483   1.00 51.01  ? 56  PHE C CD2 1 
ATOM   7595  C CE1 . PHE C 1 56  ? 38.492  10.659  7.149   1.00 42.82  ? 56  PHE C CE1 1 
ATOM   7596  C CE2 . PHE C 1 56  ? 39.964  12.497  6.815   1.00 48.26  ? 56  PHE C CE2 1 
ATOM   7597  C CZ  . PHE C 1 56  ? 39.151  11.760  7.644   1.00 44.59  ? 56  PHE C CZ  1 
ATOM   7598  N N   . PRO C 1 57  ? 39.087  11.807  0.239   1.00 56.32  ? 57  PRO C N   1 
ATOM   7599  C CA  . PRO C 1 57  ? 39.448  11.533  -1.163  1.00 52.03  ? 57  PRO C CA  1 
ATOM   7600  C C   . PRO C 1 57  ? 40.605  10.561  -1.393  1.00 48.85  ? 57  PRO C C   1 
ATOM   7601  O O   . PRO C 1 57  ? 40.566  9.774   -2.349  1.00 48.21  ? 57  PRO C O   1 
ATOM   7602  C CB  . PRO C 1 57  ? 39.764  12.934  -1.702  1.00 54.62  ? 57  PRO C CB  1 
ATOM   7603  C CG  . PRO C 1 57  ? 38.784  13.818  -0.928  1.00 58.86  ? 57  PRO C CG  1 
ATOM   7604  C CD  . PRO C 1 57  ? 38.797  13.234  0.478   1.00 55.33  ? 57  PRO C CD  1 
ATOM   7605  N N   . ASP C 1 58  ? 41.584  10.551  -0.479  1.00 41.53  ? 58  ASP C N   1 
ATOM   7606  C CA  . ASP C 1 58  ? 42.786  9.756   -0.639  1.00 50.97  ? 58  ASP C CA  1 
ATOM   7607  C C   . ASP C 1 58  ? 42.816  8.543   0.275   1.00 45.92  ? 58  ASP C C   1 
ATOM   7608  O O   . ASP C 1 58  ? 43.840  7.866   0.295   1.00 47.52  ? 58  ASP C O   1 
ATOM   7609  C CB  . ASP C 1 58  ? 44.058  10.566  -0.354  1.00 59.18  ? 58  ASP C CB  1 
ATOM   7610  C CG  . ASP C 1 58  ? 44.267  11.746  -1.291  1.00 66.92  ? 58  ASP C CG  1 
ATOM   7611  O OD1 . ASP C 1 58  ? 43.346  12.063  -2.082  1.00 73.17  ? 58  ASP C OD1 1 
ATOM   7612  O OD2 . ASP C 1 58  ? 45.354  12.339  -1.230  1.00 81.65  ? 58  ASP C OD2 1 
ATOM   7613  N N   . GLU C 1 59  ? 41.735  8.249   1.015   1.00 41.99  ? 59  GLU C N   1 
ATOM   7614  C CA  . GLU C 1 59  ? 41.729  7.059   1.855   1.00 45.15  ? 59  GLU C CA  1 
ATOM   7615  C C   . GLU C 1 59  ? 40.406  6.278   1.766   1.00 39.04  ? 59  GLU C C   1 
ATOM   7616  O O   . GLU C 1 59  ? 40.386  5.079   2.019   1.00 40.62  ? 59  GLU C O   1 
ATOM   7617  C CB  . GLU C 1 59  ? 41.974  7.392   3.330   1.00 44.20  ? 59  GLU C CB  1 
ATOM   7618  C CG  . GLU C 1 59  ? 43.287  8.076   3.648   1.00 52.77  ? 59  GLU C CG  1 
ATOM   7619  C CD  . GLU C 1 59  ? 43.468  8.336   5.142   1.00 49.04  ? 59  GLU C CD  1 
ATOM   7620  O OE1 . GLU C 1 59  ? 43.543  7.356   5.914   1.00 51.50  ? 59  GLU C OE1 1 
ATOM   7621  O OE2 . GLU C 1 59  ? 43.462  9.510   5.540   1.00 51.54  ? 59  GLU C OE2 1 
ATOM   7622  N N   . GLY C 1 60  ? 39.304  6.971   1.494   1.00 38.49  ? 60  GLY C N   1 
ATOM   7623  C CA  . GLY C 1 60  ? 37.978  6.376   1.503   1.00 41.73  ? 60  GLY C CA  1 
ATOM   7624  C C   . GLY C 1 60  ? 37.284  6.590   2.847   1.00 45.23  ? 60  GLY C C   1 
ATOM   7625  O O   . GLY C 1 60  ? 37.688  7.443   3.642   1.00 41.18  ? 60  GLY C O   1 
ATOM   7626  N N   . VAL C 1 61  ? 36.214  5.820   3.075   1.00 36.87  ? 61  VAL C N   1 
ATOM   7627  C CA  . VAL C 1 61  ? 35.295  6.158   4.136   1.00 32.51  ? 61  VAL C CA  1 
ATOM   7628  C C   . VAL C 1 61  ? 35.955  5.745   5.433   1.00 28.13  ? 61  VAL C C   1 
ATOM   7629  O O   . VAL C 1 61  ? 36.670  4.750   5.487   1.00 34.20  ? 61  VAL C O   1 
ATOM   7630  C CB  . VAL C 1 61  ? 33.904  5.508   3.916   1.00 33.67  ? 61  VAL C CB  1 
ATOM   7631  C CG1 . VAL C 1 61  ? 33.948  4.001   3.851   1.00 32.16  ? 61  VAL C CG1 1 
ATOM   7632  C CG2 . VAL C 1 61  ? 32.898  5.938   4.969   1.00 36.58  ? 61  VAL C CG2 1 
ATOM   7633  N N   . LYS C 1 62  ? 35.663  6.500   6.489   1.00 31.94  ? 62  LYS C N   1 
ATOM   7634  C CA  . LYS C 1 62  ? 36.001  6.101   7.842   1.00 33.21  ? 62  LYS C CA  1 
ATOM   7635  C C   . LYS C 1 62  ? 34.728  6.198   8.666   1.00 28.73  ? 62  LYS C C   1 
ATOM   7636  O O   . LYS C 1 62  ? 33.979  7.145   8.505   1.00 31.69  ? 62  LYS C O   1 
ATOM   7637  C CB  . LYS C 1 62  ? 37.082  7.030   8.414   1.00 37.94  ? 62  LYS C CB  1 
ATOM   7638  C CG  . LYS C 1 62  ? 38.472  6.854   7.803   1.00 37.80  ? 62  LYS C CG  1 
ATOM   7639  C CD  . LYS C 1 62  ? 39.576  7.646   8.528   1.00 44.77  ? 62  LYS C CD  1 
ATOM   7640  C CE  . LYS C 1 62  ? 40.780  7.948   7.649   1.00 46.57  ? 62  LYS C CE  1 
ATOM   7641  N NZ  . LYS C 1 62  ? 42.023  7.987   8.450   1.00 49.46  ? 62  LYS C NZ  1 
ATOM   7642  N N   . PHE C 1 63  ? 34.488  5.200   9.508   1.00 30.24  ? 63  PHE C N   1 
ATOM   7643  C CA  . PHE C 1 63  ? 33.323  5.176   10.366  1.00 32.66  ? 63  PHE C CA  1 
ATOM   7644  C C   . PHE C 1 63  ? 33.774  5.654   11.737  1.00 29.26  ? 63  PHE C C   1 
ATOM   7645  O O   . PHE C 1 63  ? 34.544  4.962   12.368  1.00 30.46  ? 63  PHE C O   1 
ATOM   7646  C CB  . PHE C 1 63  ? 32.763  3.758   10.448  1.00 29.43  ? 63  PHE C CB  1 
ATOM   7647  C CG  . PHE C 1 63  ? 32.314  3.183   9.124   1.00 32.78  ? 63  PHE C CG  1 
ATOM   7648  C CD1 . PHE C 1 63  ? 31.471  3.906   8.296   1.00 31.23  ? 63  PHE C CD1 1 
ATOM   7649  C CD2 . PHE C 1 63  ? 32.681  1.907   8.733   1.00 36.10  ? 63  PHE C CD2 1 
ATOM   7650  C CE1 . PHE C 1 63  ? 31.026  3.373   7.093   1.00 34.98  ? 63  PHE C CE1 1 
ATOM   7651  C CE2 . PHE C 1 63  ? 32.251  1.381   7.521   1.00 38.95  ? 63  PHE C CE2 1 
ATOM   7652  C CZ  . PHE C 1 63  ? 31.405  2.111   6.711   1.00 31.83  ? 63  PHE C CZ  1 
ATOM   7653  N N   . ARG C 1 64  ? 33.312  6.820   12.161  1.00 28.77  ? 64  ARG C N   1 
ATOM   7654  C CA  . ARG C 1 64  ? 33.760  7.412   13.420  1.00 34.93  ? 64  ARG C CA  1 
ATOM   7655  C C   . ARG C 1 64  ? 35.286  7.311   13.580  1.00 34.89  ? 64  ARG C C   1 
ATOM   7656  O O   . ARG C 1 64  ? 35.781  6.956   14.644  1.00 36.97  ? 64  ARG C O   1 
ATOM   7657  C CB  . ARG C 1 64  ? 33.052  6.737   14.600  1.00 36.69  ? 64  ARG C CB  1 
ATOM   7658  C CG  . ARG C 1 64  ? 31.573  7.076   14.710  1.00 33.92  ? 64  ARG C CG  1 
ATOM   7659  C CD  . ARG C 1 64  ? 31.347  8.513   15.145  1.00 35.83  ? 64  ARG C CD  1 
ATOM   7660  N NE  . ARG C 1 64  ? 30.004  8.639   15.671  1.00 33.87  ? 64  ARG C NE  1 
ATOM   7661  C CZ  . ARG C 1 64  ? 29.505  9.698   16.294  1.00 34.98  ? 64  ARG C CZ  1 
ATOM   7662  N NH1 . ARG C 1 64  ? 30.255  10.749  16.558  1.00 34.75  ? 64  ARG C NH1 1 
ATOM   7663  N NH2 . ARG C 1 64  ? 28.224  9.719   16.611  1.00 34.22  ? 64  ARG C NH2 1 
ATOM   7664  N N   . GLY C 1 65  ? 36.030  7.620   12.513  1.00 37.55  ? 65  GLY C N   1 
ATOM   7665  C CA  . GLY C 1 65  ? 37.482  7.737   12.568  1.00 33.45  ? 65  GLY C CA  1 
ATOM   7666  C C   . GLY C 1 65  ? 38.198  6.408   12.348  1.00 36.97  ? 65  GLY C C   1 
ATOM   7667  O O   . GLY C 1 65  ? 39.425  6.383   12.269  1.00 34.76  ? 65  GLY C O   1 
ATOM   7668  N N   . TYR C 1 66  ? 37.443  5.302   12.216  1.00 31.23  ? 66  TYR C N   1 
ATOM   7669  C CA  . TYR C 1 66  ? 38.065  4.007   12.000  1.00 31.23  ? 66  TYR C CA  1 
ATOM   7670  C C   . TYR C 1 66  ? 37.968  3.584   10.539  1.00 35.21  ? 66  TYR C C   1 
ATOM   7671  O O   . TYR C 1 66  ? 36.968  3.805   9.875   1.00 37.32  ? 66  TYR C O   1 
ATOM   7672  C CB  . TYR C 1 66  ? 37.452  2.936   12.887  1.00 35.23  ? 66  TYR C CB  1 
ATOM   7673  C CG  . TYR C 1 66  ? 37.629  3.140   14.366  1.00 40.77  ? 66  TYR C CG  1 
ATOM   7674  C CD1 . TYR C 1 66  ? 38.785  2.744   15.025  1.00 40.79  ? 66  TYR C CD1 1 
ATOM   7675  C CD2 . TYR C 1 66  ? 36.627  3.737   15.116  1.00 41.22  ? 66  TYR C CD2 1 
ATOM   7676  C CE1 . TYR C 1 66  ? 38.929  2.899   16.398  1.00 37.38  ? 66  TYR C CE1 1 
ATOM   7677  C CE2 . TYR C 1 66  ? 36.770  3.920   16.480  1.00 42.21  ? 66  TYR C CE2 1 
ATOM   7678  C CZ  . TYR C 1 66  ? 37.927  3.516   17.118  1.00 36.10  ? 66  TYR C CZ  1 
ATOM   7679  O OH  . TYR C 1 66  ? 38.008  3.695   18.463  1.00 37.89  ? 66  TYR C OH  1 
ATOM   7680  N N   . THR C 1 67  ? 39.021  2.948   10.026  1.00 37.55  ? 67  THR C N   1 
ATOM   7681  C CA  . THR C 1 67  ? 39.036  2.522   8.642   1.00 32.71  ? 67  THR C CA  1 
ATOM   7682  C C   . THR C 1 67  ? 38.344  1.162   8.583   1.00 32.24  ? 67  THR C C   1 
ATOM   7683  O O   . THR C 1 67  ? 38.205  0.440   9.585   1.00 36.92  ? 67  THR C O   1 
ATOM   7684  C CB  . THR C 1 67  ? 40.455  2.339   8.085   1.00 34.68  ? 67  THR C CB  1 
ATOM   7685  O OG1 . THR C 1 67  ? 40.980  1.255   8.851   1.00 33.77  ? 67  THR C OG1 1 
ATOM   7686  C CG2 . THR C 1 67  ? 41.331  3.568   8.200   1.00 41.59  ? 67  THR C CG2 1 
ATOM   7687  N N   . ILE C 1 68  ? 37.997  0.764   7.375   1.00 32.65  ? 68  ILE C N   1 
ATOM   7688  C CA  . ILE C 1 68  ? 37.396  -0.540  7.202   1.00 33.61  ? 68  ILE C CA  1 
ATOM   7689  C C   . ILE C 1 68  ? 38.350  -1.652  7.642   1.00 36.40  ? 68  ILE C C   1 
ATOM   7690  O O   . ILE C 1 68  ? 37.922  -2.548  8.361   1.00 35.70  ? 68  ILE C O   1 
ATOM   7691  C CB  . ILE C 1 68  ? 36.863  -0.688  5.764   1.00 36.22  ? 68  ILE C CB  1 
ATOM   7692  C CG1 . ILE C 1 68  ? 35.606  0.178   5.622   1.00 37.89  ? 68  ILE C CG1 1 
ATOM   7693  C CG2 . ILE C 1 68  ? 36.620  -2.157  5.441   1.00 33.81  ? 68  ILE C CG2 1 
ATOM   7694  C CD1 . ILE C 1 68  ? 35.142  0.376   4.208   1.00 39.14  ? 68  ILE C CD1 1 
ATOM   7695  N N   . PRO C 1 69  ? 39.649  -1.701  7.263   1.00 36.64  ? 69  PRO C N   1 
ATOM   7696  C CA  . PRO C 1 69  ? 40.523  -2.759  7.793   1.00 37.32  ? 69  PRO C CA  1 
ATOM   7697  C C   . PRO C 1 69  ? 40.659  -2.820  9.315   1.00 33.28  ? 69  PRO C C   1 
ATOM   7698  O O   . PRO C 1 69  ? 40.758  -3.906  9.869   1.00 41.09  ? 69  PRO C O   1 
ATOM   7699  C CB  . PRO C 1 69  ? 41.875  -2.449  7.120   1.00 44.10  ? 69  PRO C CB  1 
ATOM   7700  C CG  . PRO C 1 69  ? 41.509  -1.738  5.845   1.00 41.00  ? 69  PRO C CG  1 
ATOM   7701  C CD  . PRO C 1 69  ? 40.303  -0.891  6.226   1.00 38.63  ? 69  PRO C CD  1 
ATOM   7702  N N   . GLU C 1 70  ? 40.644  -1.678  10.008  1.00 33.34  ? 70  GLU C N   1 
ATOM   7703  C CA  . GLU C 1 70  ? 40.718  -1.673  11.466  1.00 35.23  ? 70  GLU C CA  1 
ATOM   7704  C C   . GLU C 1 70  ? 39.522  -2.417  12.070  1.00 37.90  ? 70  GLU C C   1 
ATOM   7705  O O   . GLU C 1 70  ? 39.706  -3.185  13.016  1.00 37.39  ? 70  GLU C O   1 
ATOM   7706  C CB  . GLU C 1 70  ? 40.765  -0.248  12.033  1.00 38.93  ? 70  GLU C CB  1 
ATOM   7707  C CG  . GLU C 1 70  ? 42.143  0.395   12.007  1.00 48.09  ? 70  GLU C CG  1 
ATOM   7708  C CD  . GLU C 1 70  ? 42.199  1.922   11.964  1.00 53.22  ? 70  GLU C CD  1 
ATOM   7709  O OE1 . GLU C 1 70  ? 43.325  2.455   11.881  1.00 62.75  ? 70  GLU C OE1 1 
ATOM   7710  O OE2 . GLU C 1 70  ? 41.131  2.592   11.943  1.00 45.77  ? 70  GLU C OE2 1 
ATOM   7711  N N   . LEU C 1 71  ? 38.311  -2.238  11.494  1.00 33.09  ? 71  LEU C N   1 
ATOM   7712  C CA  . LEU C 1 71  ? 37.086  -2.839  12.023  1.00 30.94  ? 71  LEU C CA  1 
ATOM   7713  C C   . LEU C 1 71  ? 36.878  -4.282  11.583  1.00 30.87  ? 71  LEU C C   1 
ATOM   7714  O O   . LEU C 1 71  ? 36.156  -5.035  12.243  1.00 31.21  ? 71  LEU C O   1 
ATOM   7715  C CB  . LEU C 1 71  ? 35.906  -1.971  11.569  1.00 31.72  ? 71  LEU C CB  1 
ATOM   7716  C CG  . LEU C 1 71  ? 35.973  -0.549  12.106  1.00 31.91  ? 71  LEU C CG  1 
ATOM   7717  C CD1 . LEU C 1 71  ? 34.918  0.338   11.505  1.00 34.20  ? 71  LEU C CD1 1 
ATOM   7718  C CD2 . LEU C 1 71  ? 35.886  -0.536  13.626  1.00 35.20  ? 71  LEU C CD2 1 
ATOM   7719  N N   . ARG C 1 72  ? 37.398  -4.631  10.402  1.00 32.89  ? 72  ARG C N   1 
ATOM   7720  C CA  . ARG C 1 72  ? 37.171  -5.939  9.802   1.00 38.26  ? 72  ARG C CA  1 
ATOM   7721  C C   . ARG C 1 72  ? 38.322  -6.902  10.100  1.00 39.76  ? 72  ARG C C   1 
ATOM   7722  O O   . ARG C 1 72  ? 38.113  -8.096  10.308  1.00 36.70  ? 72  ARG C O   1 
ATOM   7723  C CB  . ARG C 1 72  ? 37.021  -5.782  8.282   1.00 39.06  ? 72  ARG C CB  1 
ATOM   7724  C CG  . ARG C 1 72  ? 36.756  -7.085  7.538   1.00 36.24  ? 72  ARG C CG  1 
ATOM   7725  C CD  . ARG C 1 72  ? 36.430  -6.791  6.094   1.00 35.78  ? 72  ARG C CD  1 
ATOM   7726  N NE  . ARG C 1 72  ? 36.323  -8.079  5.473   1.00 36.77  ? 72  ARG C NE  1 
ATOM   7727  C CZ  . ARG C 1 72  ? 37.295  -8.679  4.805   1.00 40.05  ? 72  ARG C CZ  1 
ATOM   7728  N NH1 . ARG C 1 72  ? 38.399  -8.019  4.490   1.00 40.76  ? 72  ARG C NH1 1 
ATOM   7729  N NH2 . ARG C 1 72  ? 37.124  -9.920  4.395   1.00 38.86  ? 72  ARG C NH2 1 
ATOM   7730  N N   . GLU C 1 73  ? 39.542  -6.375  10.040  1.00 40.00  ? 73  GLU C N   1 
ATOM   7731  C CA  . GLU C 1 73  ? 40.758  -7.160  10.214  1.00 50.70  ? 73  GLU C CA  1 
ATOM   7732  C C   . GLU C 1 73  ? 41.496  -6.653  11.442  1.00 49.72  ? 73  GLU C C   1 
ATOM   7733  O O   . GLU C 1 73  ? 41.751  -7.427  12.333  1.00 51.96  ? 73  GLU C O   1 
ATOM   7734  C CB  . GLU C 1 73  ? 41.724  -6.987  9.038   1.00 49.17  ? 73  GLU C CB  1 
ATOM   7735  C CG  . GLU C 1 73  ? 41.237  -7.586  7.734   1.00 64.86  ? 73  GLU C CG  1 
ATOM   7736  C CD  . GLU C 1 73  ? 42.007  -7.205  6.471   1.00 72.66  ? 73  GLU C CD  1 
ATOM   7737  O OE1 . GLU C 1 73  ? 41.548  -7.599  5.365   1.00 73.05  ? 73  GLU C OE1 1 
ATOM   7738  O OE2 . GLU C 1 73  ? 43.057  -6.529  6.580   1.00 69.18  ? 73  GLU C OE2 1 
ATOM   7739  N N   . GLY C 1 74  ? 41.722  -5.329  11.459  1.00 58.58  ? 74  GLY C N   1 
ATOM   7740  C CA  . GLY C 1 74  ? 42.838  -4.650  12.103  1.00 53.29  ? 74  GLY C CA  1 
ATOM   7741  C C   . GLY C 1 74  ? 42.787  -4.808  13.609  1.00 60.34  ? 74  GLY C C   1 
ATOM   7742  O O   . GLY C 1 74  ? 42.211  -5.778  14.102  1.00 72.13  ? 74  GLY C O   1 
ATOM   7743  N N   . PRO C 1 75  ? 43.407  -3.884  14.383  1.00 56.63  ? 75  PRO C N   1 
ATOM   7744  C CA  . PRO C 1 75  ? 43.464  -4.044  15.837  1.00 54.87  ? 75  PRO C CA  1 
ATOM   7745  C C   . PRO C 1 75  ? 42.144  -3.745  16.562  1.00 54.63  ? 75  PRO C C   1 
ATOM   7746  O O   . PRO C 1 75  ? 42.042  -3.950  17.765  1.00 44.82  ? 75  PRO C O   1 
ATOM   7747  C CB  . PRO C 1 75  ? 44.571  -3.055  16.267  1.00 50.67  ? 75  PRO C CB  1 
ATOM   7748  C CG  . PRO C 1 75  ? 44.642  -2.011  15.151  1.00 51.41  ? 75  PRO C CG  1 
ATOM   7749  C CD  . PRO C 1 75  ? 44.131  -2.690  13.894  1.00 54.07  ? 75  PRO C CD  1 
ATOM   7750  N N   . HIS C 1 76  ? 41.134  -3.231  15.846  1.00 53.86  ? 76  HIS C N   1 
ATOM   7751  C CA  . HIS C 1 76  ? 39.898  -2.793  16.478  1.00 46.19  ? 76  HIS C CA  1 
ATOM   7752  C C   . HIS C 1 76  ? 38.717  -3.616  15.986  1.00 42.33  ? 76  HIS C C   1 
ATOM   7753  O O   . HIS C 1 76  ? 37.655  -3.075  15.717  1.00 41.02  ? 76  HIS C O   1 
ATOM   7754  C CB  . HIS C 1 76  ? 39.690  -1.316  16.169  1.00 43.39  ? 76  HIS C CB  1 
ATOM   7755  C CG  . HIS C 1 76  ? 40.740  -0.494  16.810  1.00 49.27  ? 76  HIS C CG  1 
ATOM   7756  N ND1 . HIS C 1 76  ? 40.964  -0.585  18.172  1.00 49.24  ? 76  HIS C ND1 1 
ATOM   7757  C CD2 . HIS C 1 76  ? 41.616  0.403   16.311  1.00 44.18  ? 76  HIS C CD2 1 
ATOM   7758  C CE1 . HIS C 1 76  ? 41.944  0.246   18.497  1.00 50.26  ? 76  HIS C CE1 1 
ATOM   7759  N NE2 . HIS C 1 76  ? 42.344  0.862   17.387  1.00 53.66  ? 76  HIS C NE2 1 
ATOM   7760  N N   . LYS C 1 77  ? 38.915  -4.921  15.850  1.00 37.87  ? 77  LYS C N   1 
ATOM   7761  C CA  . LYS C 1 77  ? 37.984  -5.716  15.071  1.00 40.77  ? 77  LYS C CA  1 
ATOM   7762  C C   . LYS C 1 77  ? 36.629  -5.765  15.776  1.00 39.68  ? 77  LYS C C   1 
ATOM   7763  O O   . LYS C 1 77  ? 36.543  -6.086  16.951  1.00 38.29  ? 77  LYS C O   1 
ATOM   7764  C CB  . LYS C 1 77  ? 38.587  -7.103  14.853  1.00 41.46  ? 77  LYS C CB  1 
ATOM   7765  C CG  . LYS C 1 77  ? 37.844  -7.976  13.846  1.00 47.31  ? 77  LYS C CG  1 
ATOM   7766  C CD  . LYS C 1 77  ? 38.459  -9.349  13.719  1.00 47.64  ? 77  LYS C CD  1 
ATOM   7767  C CE  . LYS C 1 77  ? 37.491  -10.402 13.226  1.00 50.74  ? 77  LYS C CE  1 
ATOM   7768  N NZ  . LYS C 1 77  ? 37.245  -10.256 11.782  1.00 46.75  ? 77  LYS C NZ  1 
ATOM   7769  N N   . LEU C 1 78  ? 35.553  -5.478  15.045  1.00 37.73  ? 78  LEU C N   1 
ATOM   7770  C CA  . LEU C 1 78  ? 34.215  -5.585  15.605  1.00 35.04  ? 78  LEU C CA  1 
ATOM   7771  C C   . LEU C 1 78  ? 33.845  -7.035  15.873  1.00 31.90  ? 78  LEU C C   1 
ATOM   7772  O O   . LEU C 1 78  ? 34.294  -7.964  15.211  1.00 32.56  ? 78  LEU C O   1 
ATOM   7773  C CB  . LEU C 1 78  ? 33.203  -4.956  14.638  1.00 33.97  ? 78  LEU C CB  1 
ATOM   7774  C CG  . LEU C 1 78  ? 33.254  -3.450  14.506  1.00 33.93  ? 78  LEU C CG  1 
ATOM   7775  C CD1 . LEU C 1 78  ? 32.362  -2.966  13.365  1.00 38.17  ? 78  LEU C CD1 1 
ATOM   7776  C CD2 . LEU C 1 78  ? 32.885  -2.773  15.806  1.00 37.52  ? 78  LEU C CD2 1 
ATOM   7777  N N   . PRO C 1 79  ? 32.925  -7.282  16.823  1.00 33.16  ? 79  PRO C N   1 
ATOM   7778  C CA  . PRO C 1 79  ? 32.408  -8.629  17.028  1.00 34.12  ? 79  PRO C CA  1 
ATOM   7779  C C   . PRO C 1 79  ? 31.823  -9.252  15.757  1.00 34.22  ? 79  PRO C C   1 
ATOM   7780  O O   . PRO C 1 79  ? 31.244  -8.562  14.918  1.00 32.31  ? 79  PRO C O   1 
ATOM   7781  C CB  . PRO C 1 79  ? 31.335  -8.411  18.087  1.00 33.94  ? 79  PRO C CB  1 
ATOM   7782  C CG  . PRO C 1 79  ? 31.826  -7.195  18.849  1.00 35.40  ? 79  PRO C CG  1 
ATOM   7783  C CD  . PRO C 1 79  ? 32.412  -6.305  17.781  1.00 35.33  ? 79  PRO C CD  1 
ATOM   7784  N N   . THR C 1 80  ? 31.963  -10.575 15.668  1.00 32.21  ? 80  THR C N   1 
ATOM   7785  C CA  . THR C 1 80  ? 31.507  -11.385 14.562  1.00 34.44  ? 80  THR C CA  1 
ATOM   7786  C C   . THR C 1 80  ? 30.390  -12.277 15.083  1.00 39.28  ? 80  THR C C   1 
ATOM   7787  O O   . THR C 1 80  ? 30.069  -12.218 16.271  1.00 37.32  ? 80  THR C O   1 
ATOM   7788  C CB  . THR C 1 80  ? 32.681  -12.232 14.054  1.00 36.48  ? 80  THR C CB  1 
ATOM   7789  O OG1 . THR C 1 80  ? 32.970  -13.206 15.064  1.00 37.51  ? 80  THR C OG1 1 
ATOM   7790  C CG2 . THR C 1 80  ? 33.905  -11.397 13.772  1.00 35.52  ? 80  THR C CG2 1 
ATOM   7791  N N   . ALA C 1 81  ? 29.825  -13.110 14.202  1.00 37.81  ? 81  ALA C N   1 
ATOM   7792  C CA  . ALA C 1 81  ? 29.010  -14.221 14.640  1.00 38.38  ? 81  ALA C CA  1 
ATOM   7793  C C   . ALA C 1 81  ? 29.943  -15.268 15.232  1.00 40.73  ? 81  ALA C C   1 
ATOM   7794  O O   . ALA C 1 81  ? 31.133  -15.251 14.947  1.00 39.96  ? 81  ALA C O   1 
ATOM   7795  C CB  . ALA C 1 81  ? 28.222  -14.772 13.483  1.00 40.18  ? 81  ALA C CB  1 
ATOM   7796  N N   . GLU C 1 82  ? 29.397  -16.187 16.027  1.00 42.49  ? 82  GLU C N   1 
ATOM   7797  C CA  . GLU C 1 82  ? 30.172  -17.306 16.548  1.00 45.02  ? 82  GLU C CA  1 
ATOM   7798  C C   . GLU C 1 82  ? 30.720  -18.175 15.409  1.00 39.89  ? 82  GLU C C   1 
ATOM   7799  O O   . GLU C 1 82  ? 29.974  -18.680 14.577  1.00 45.14  ? 82  GLU C O   1 
ATOM   7800  C CB  . GLU C 1 82  ? 29.266  -18.136 17.464  1.00 56.62  ? 82  GLU C CB  1 
ATOM   7801  C CG  . GLU C 1 82  ? 29.974  -19.302 18.139  1.00 68.97  ? 82  GLU C CG  1 
ATOM   7802  C CD  . GLU C 1 82  ? 29.111  -20.546 18.269  1.00 86.71  ? 82  GLU C CD  1 
ATOM   7803  O OE1 . GLU C 1 82  ? 29.415  -21.555 17.589  1.00 92.63  ? 82  GLU C OE1 1 
ATOM   7804  O OE2 . GLU C 1 82  ? 28.121  -20.495 19.030  1.00 101.45 ? 82  GLU C OE2 1 
ATOM   7805  N N   . GLY C 1 83  ? 32.032  -18.408 15.378  1.00 38.76  ? 83  GLY C N   1 
ATOM   7806  C CA  . GLY C 1 83  ? 32.656  -19.140 14.278  1.00 39.91  ? 83  GLY C CA  1 
ATOM   7807  C C   . GLY C 1 83  ? 32.830  -18.294 13.013  1.00 39.86  ? 83  GLY C C   1 
ATOM   7808  O O   . GLY C 1 83  ? 33.211  -18.814 11.978  1.00 44.26  ? 83  GLY C O   1 
ATOM   7809  N N   . GLY C 1 84  ? 32.556  -16.984 13.096  1.00 39.95  ? 84  GLY C N   1 
ATOM   7810  C CA  . GLY C 1 84  ? 32.562  -16.113 11.930  1.00 39.18  ? 84  GLY C CA  1 
ATOM   7811  C C   . GLY C 1 84  ? 33.800  -15.218 11.851  1.00 38.28  ? 84  GLY C C   1 
ATOM   7812  O O   . GLY C 1 84  ? 34.557  -15.095 12.793  1.00 36.35  ? 84  GLY C O   1 
ATOM   7813  N N   . PHE C 1 85  ? 34.025  -14.635 10.673  1.00 39.79  ? 85  PHE C N   1 
ATOM   7814  C CA  . PHE C 1 85  ? 35.112  -13.697 10.461  1.00 39.13  ? 85  PHE C CA  1 
ATOM   7815  C C   . PHE C 1 85  ? 34.553  -12.304 10.165  1.00 35.13  ? 85  PHE C C   1 
ATOM   7816  O O   . PHE C 1 85  ? 35.097  -11.311 10.616  1.00 32.80  ? 85  PHE C O   1 
ATOM   7817  C CB  . PHE C 1 85  ? 35.995  -14.166 9.308   1.00 39.86  ? 85  PHE C CB  1 
ATOM   7818  C CG  . PHE C 1 85  ? 37.128  -13.216 9.027   1.00 45.16  ? 85  PHE C CG  1 
ATOM   7819  C CD1 . PHE C 1 85  ? 38.276  -13.237 9.814   1.00 48.41  ? 85  PHE C CD1 1 
ATOM   7820  C CD2 . PHE C 1 85  ? 37.011  -12.245 8.043   1.00 42.39  ? 85  PHE C CD2 1 
ATOM   7821  C CE1 . PHE C 1 85  ? 39.297  -12.327 9.583   1.00 45.03  ? 85  PHE C CE1 1 
ATOM   7822  C CE2 . PHE C 1 85  ? 38.039  -11.343 7.812   1.00 46.67  ? 85  PHE C CE2 1 
ATOM   7823  C CZ  . PHE C 1 85  ? 39.181  -11.386 8.586   1.00 44.58  ? 85  PHE C CZ  1 
ATOM   7824  N N   . GLU C 1 86  ? 33.455  -12.210 9.402   1.00 35.71  ? 86  GLU C N   1 
ATOM   7825  C CA  . GLU C 1 86  ? 32.969  -10.905 8.971   1.00 34.72  ? 86  GLU C CA  1 
ATOM   7826  C C   . GLU C 1 86  ? 32.342  -10.171 10.147  1.00 31.53  ? 86  GLU C C   1 
ATOM   7827  O O   . GLU C 1 86  ? 31.606  -10.757 10.937  1.00 34.66  ? 86  GLU C O   1 
ATOM   7828  C CB  . GLU C 1 86  ? 31.996  -11.027 7.787   1.00 33.41  ? 86  GLU C CB  1 
ATOM   7829  C CG  . GLU C 1 86  ? 32.666  -11.628 6.545   1.00 32.70  ? 86  GLU C CG  1 
ATOM   7830  C CD  . GLU C 1 86  ? 33.885  -10.872 6.021   1.00 36.19  ? 86  GLU C CD  1 
ATOM   7831  O OE1 . GLU C 1 86  ? 34.711  -11.480 5.273   1.00 37.45  ? 86  GLU C OE1 1 
ATOM   7832  O OE2 . GLU C 1 86  ? 33.998  -9.649  6.309   1.00 34.56  ? 86  GLU C OE2 1 
ATOM   7833  N N   . PRO C 1 87  ? 32.586  -8.856  10.271  1.00 30.94  ? 87  PRO C N   1 
ATOM   7834  C CA  . PRO C 1 87  ? 31.992  -8.060  11.341  1.00 33.08  ? 87  PRO C CA  1 
ATOM   7835  C C   . PRO C 1 87  ? 30.467  -7.925  11.240  1.00 36.54  ? 87  PRO C C   1 
ATOM   7836  O O   . PRO C 1 87  ? 29.934  -7.772  10.150  1.00 32.41  ? 87  PRO C O   1 
ATOM   7837  C CB  . PRO C 1 87  ? 32.630  -6.687  11.136  1.00 36.24  ? 87  PRO C CB  1 
ATOM   7838  C CG  . PRO C 1 87  ? 32.954  -6.620  9.667   1.00 33.84  ? 87  PRO C CG  1 
ATOM   7839  C CD  . PRO C 1 87  ? 33.305  -8.038  9.288   1.00 33.27  ? 87  PRO C CD  1 
ATOM   7840  N N   . LEU C 1 88  ? 29.771  -7.972  12.382  1.00 36.06  ? 88  LEU C N   1 
ATOM   7841  C CA  . LEU C 1 88  ? 28.328  -7.809  12.404  1.00 36.64  ? 88  LEU C CA  1 
ATOM   7842  C C   . LEU C 1 88  ? 27.970  -6.342  12.255  1.00 34.00  ? 88  LEU C C   1 
ATOM   7843  O O   . LEU C 1 88  ? 28.471  -5.477  12.982  1.00 32.20  ? 88  LEU C O   1 
ATOM   7844  C CB  . LEU C 1 88  ? 27.757  -8.360  13.710  1.00 37.99  ? 88  LEU C CB  1 
ATOM   7845  C CG  . LEU C 1 88  ? 27.974  -9.850  13.912  1.00 36.19  ? 88  LEU C CG  1 
ATOM   7846  C CD1 . LEU C 1 88  ? 27.279  -10.336 15.163  1.00 36.54  ? 88  LEU C CD1 1 
ATOM   7847  C CD2 . LEU C 1 88  ? 27.470  -10.611 12.715  1.00 38.46  ? 88  LEU C CD2 1 
ATOM   7848  N N   . PRO C 1 89  ? 27.016  -6.021  11.353  1.00 32.56  ? 89  PRO C N   1 
ATOM   7849  C CA  . PRO C 1 89  ? 26.490  -4.669  11.268  1.00 30.40  ? 89  PRO C CA  1 
ATOM   7850  C C   . PRO C 1 89  ? 25.885  -4.142  12.560  1.00 28.90  ? 89  PRO C C   1 
ATOM   7851  O O   . PRO C 1 89  ? 25.963  -2.941  12.781  1.00 30.98  ? 89  PRO C O   1 
ATOM   7852  C CB  . PRO C 1 89  ? 25.396  -4.723  10.188  1.00 34.19  ? 89  PRO C CB  1 
ATOM   7853  C CG  . PRO C 1 89  ? 25.154  -6.178  9.935   1.00 32.56  ? 89  PRO C CG  1 
ATOM   7854  C CD  . PRO C 1 89  ? 26.367  -6.948  10.421  1.00 30.34  ? 89  PRO C CD  1 
ATOM   7855  N N   . GLU C 1 90  ? 25.358  -5.029  13.419  1.00 30.27  ? 90  GLU C N   1 
ATOM   7856  C CA  . GLU C 1 90  ? 24.853  -4.626  14.725  1.00 31.37  ? 90  GLU C CA  1 
ATOM   7857  C C   . GLU C 1 90  ? 25.913  -3.844  15.505  1.00 31.26  ? 90  GLU C C   1 
ATOM   7858  O O   . GLU C 1 90  ? 25.618  -2.779  16.054  1.00 32.80  ? 90  GLU C O   1 
ATOM   7859  C CB  . GLU C 1 90  ? 24.433  -5.839  15.544  1.00 34.93  ? 90  GLU C CB  1 
ATOM   7860  C CG  . GLU C 1 90  ? 23.162  -6.557  15.069  1.00 39.34  ? 90  GLU C CG  1 
ATOM   7861  C CD  . GLU C 1 90  ? 23.354  -7.775  14.181  1.00 34.12  ? 90  GLU C CD  1 
ATOM   7862  O OE1 . GLU C 1 90  ? 22.593  -8.769  14.353  1.00 33.77  ? 90  GLU C OE1 1 
ATOM   7863  O OE2 . GLU C 1 90  ? 24.240  -7.709  13.291  1.00 31.88  ? 90  GLU C OE2 1 
ATOM   7864  N N   . GLY C 1 91  ? 27.163  -4.331  15.496  1.00 32.04  ? 91  GLY C N   1 
ATOM   7865  C CA  . GLY C 1 91  ? 28.253  -3.658  16.189  1.00 31.59  ? 91  GLY C CA  1 
ATOM   7866  C C   . GLY C 1 91  ? 28.648  -2.361  15.497  1.00 30.79  ? 91  GLY C C   1 
ATOM   7867  O O   . GLY C 1 91  ? 28.937  -1.345  16.144  1.00 29.98  ? 91  GLY C O   1 
ATOM   7868  N N   . LEU C 1 92  ? 28.621  -2.370  14.157  1.00 29.89  ? 92  LEU C N   1 
ATOM   7869  C CA  . LEU C 1 92  ? 28.943  -1.146  13.437  1.00 28.83  ? 92  LEU C CA  1 
ATOM   7870  C C   . LEU C 1 92  ? 27.938  -0.051  13.809  1.00 30.85  ? 92  LEU C C   1 
ATOM   7871  O O   . LEU C 1 92  ? 28.318  1.112   13.970  1.00 28.11  ? 92  LEU C O   1 
ATOM   7872  C CB  . LEU C 1 92  ? 28.967  -1.379  11.924  1.00 31.79  ? 92  LEU C CB  1 
ATOM   7873  C CG  . LEU C 1 92  ? 29.142  -0.097  11.104  1.00 32.01  ? 92  LEU C CG  1 
ATOM   7874  C CD1 . LEU C 1 92  ? 30.450  0.560   11.439  1.00 35.67  ? 92  LEU C CD1 1 
ATOM   7875  C CD2 . LEU C 1 92  ? 29.061  -0.373  9.621   1.00 39.86  ? 92  LEU C CD2 1 
ATOM   7876  N N   . TRP C 1 93  ? 26.654  -0.422  13.943  1.00 28.42  ? 93  TRP C N   1 
ATOM   7877  C CA  . TRP C 1 93  ? 25.619  0.549   14.293  1.00 28.63  ? 93  TRP C CA  1 
ATOM   7878  C C   . TRP C 1 93  ? 25.874  1.166   15.680  1.00 29.06  ? 93  TRP C C   1 
ATOM   7879  O O   . TRP C 1 93  ? 25.720  2.373   15.833  1.00 28.18  ? 93  TRP C O   1 
ATOM   7880  C CB  . TRP C 1 93  ? 24.244  -0.122  14.199  1.00 28.16  ? 93  TRP C CB  1 
ATOM   7881  C CG  . TRP C 1 93  ? 23.078  0.819   14.191  1.00 28.12  ? 93  TRP C CG  1 
ATOM   7882  C CD1 . TRP C 1 93  ? 22.827  1.813   13.293  1.00 26.29  ? 93  TRP C CD1 1 
ATOM   7883  C CD2 . TRP C 1 93  ? 22.025  0.886   15.163  1.00 25.44  ? 93  TRP C CD2 1 
ATOM   7884  N NE1 . TRP C 1 93  ? 21.662  2.442   13.584  1.00 25.41  ? 93  TRP C NE1 1 
ATOM   7885  C CE2 . TRP C 1 93  ? 21.132  1.873   14.719  1.00 25.13  ? 93  TRP C CE2 1 
ATOM   7886  C CE3 . TRP C 1 93  ? 21.714  0.146   16.310  1.00 30.73  ? 93  TRP C CE3 1 
ATOM   7887  C CZ2 . TRP C 1 93  ? 19.980  2.201   15.436  1.00 29.61  ? 93  TRP C CZ2 1 
ATOM   7888  C CZ3 . TRP C 1 93  ? 20.563  0.452   17.010  1.00 28.66  ? 93  TRP C CZ3 1 
ATOM   7889  C CH2 . TRP C 1 93  ? 19.703  1.458   16.568  1.00 29.51  ? 93  TRP C CH2 1 
ATOM   7890  N N   . TYR C 1 94  ? 26.298  0.353   16.668  1.00 28.39  ? 94  TYR C N   1 
ATOM   7891  C CA  . TYR C 1 94  ? 26.696  0.841   17.990  1.00 30.19  ? 94  TYR C CA  1 
ATOM   7892  C C   . TYR C 1 94  ? 27.819  1.885   17.874  1.00 32.68  ? 94  TYR C C   1 
ATOM   7893  O O   . TYR C 1 94  ? 27.755  2.949   18.470  1.00 30.51  ? 94  TYR C O   1 
ATOM   7894  C CB  . TYR C 1 94  ? 27.108  -0.326  18.900  1.00 28.58  ? 94  TYR C CB  1 
ATOM   7895  C CG  . TYR C 1 94  ? 27.428  0.055   20.321  1.00 33.22  ? 94  TYR C CG  1 
ATOM   7896  C CD1 . TYR C 1 94  ? 28.623  0.673   20.642  1.00 37.54  ? 94  TYR C CD1 1 
ATOM   7897  C CD2 . TYR C 1 94  ? 26.540  -0.199  21.350  1.00 38.27  ? 94  TYR C CD2 1 
ATOM   7898  C CE1 . TYR C 1 94  ? 28.931  1.041   21.941  1.00 39.93  ? 94  TYR C CE1 1 
ATOM   7899  C CE2 . TYR C 1 94  ? 26.824  0.162   22.656  1.00 40.45  ? 94  TYR C CE2 1 
ATOM   7900  C CZ  . TYR C 1 94  ? 28.023  0.800   22.954  1.00 42.50  ? 94  TYR C CZ  1 
ATOM   7901  O OH  . TYR C 1 94  ? 28.316  1.201   24.245  1.00 41.24  ? 94  TYR C OH  1 
ATOM   7902  N N   . LEU C 1 95  ? 28.813  1.613   17.027  1.00 34.41  ? 95  LEU C N   1 
ATOM   7903  C CA  . LEU C 1 95  ? 29.879  2.558   16.758  1.00 31.41  ? 95  LEU C CA  1 
ATOM   7904  C C   . LEU C 1 95  ? 29.364  3.844   16.125  1.00 32.22  ? 95  LEU C C   1 
ATOM   7905  O O   . LEU C 1 95  ? 29.698  4.931   16.583  1.00 29.40  ? 95  LEU C O   1 
ATOM   7906  C CB  . LEU C 1 95  ? 30.936  1.878   15.889  1.00 32.80  ? 95  LEU C CB  1 
ATOM   7907  C CG  . LEU C 1 95  ? 32.097  2.763   15.426  1.00 29.85  ? 95  LEU C CG  1 
ATOM   7908  C CD1 . LEU C 1 95  ? 32.880  3.311   16.596  1.00 31.29  ? 95  LEU C CD1 1 
ATOM   7909  C CD2 . LEU C 1 95  ? 33.022  1.959   14.539  1.00 31.97  ? 95  LEU C CD2 1 
ATOM   7910  N N   . LEU C 1 96  ? 28.564  3.755   15.062  1.00 31.49  ? 96  LEU C N   1 
ATOM   7911  C CA  . LEU C 1 96  ? 28.063  4.954   14.424  1.00 30.06  ? 96  LEU C CA  1 
ATOM   7912  C C   . LEU C 1 96  ? 27.337  5.854   15.429  1.00 29.02  ? 96  LEU C C   1 
ATOM   7913  O O   . LEU C 1 96  ? 27.428  7.082   15.357  1.00 30.21  ? 96  LEU C O   1 
ATOM   7914  C CB  . LEU C 1 96  ? 27.130  4.562   13.268  1.00 31.80  ? 96  LEU C CB  1 
ATOM   7915  C CG  . LEU C 1 96  ? 27.797  3.863   12.087  1.00 30.81  ? 96  LEU C CG  1 
ATOM   7916  C CD1 . LEU C 1 96  ? 26.825  3.762   10.929  1.00 32.08  ? 96  LEU C CD1 1 
ATOM   7917  C CD2 . LEU C 1 96  ? 29.019  4.606   11.590  1.00 29.06  ? 96  LEU C CD2 1 
ATOM   7918  N N   . LEU C 1 97  ? 26.546  5.257   16.313  1.00 30.09  ? 97  LEU C N   1 
ATOM   7919  C CA  . LEU C 1 97  ? 25.736  6.039   17.247  1.00 32.45  ? 97  LEU C CA  1 
ATOM   7920  C C   . LEU C 1 97  ? 26.584  6.694   18.351  1.00 30.82  ? 97  LEU C C   1 
ATOM   7921  O O   . LEU C 1 97  ? 26.379  7.863   18.682  1.00 32.57  ? 97  LEU C O   1 
ATOM   7922  C CB  . LEU C 1 97  ? 24.677  5.099   17.840  1.00 29.88  ? 97  LEU C CB  1 
ATOM   7923  C CG  . LEU C 1 97  ? 23.422  4.985   16.967  1.00 29.31  ? 97  LEU C CG  1 
ATOM   7924  C CD1 . LEU C 1 97  ? 22.477  3.929   17.482  1.00 33.18  ? 97  LEU C CD1 1 
ATOM   7925  C CD2 . LEU C 1 97  ? 22.733  6.318   16.905  1.00 36.46  ? 97  LEU C CD2 1 
ATOM   7926  N N   . THR C 1 98  ? 27.503  5.926   18.935  1.00 30.32  ? 98  THR C N   1 
ATOM   7927  C CA  . THR C 1 98  ? 28.167  6.343   20.159  1.00 34.48  ? 98  THR C CA  1 
ATOM   7928  C C   . THR C 1 98  ? 29.540  6.949   19.890  1.00 36.86  ? 98  THR C C   1 
ATOM   7929  O O   . THR C 1 98  ? 30.015  7.723   20.708  1.00 33.52  ? 98  THR C O   1 
ATOM   7930  C CB  . THR C 1 98  ? 28.382  5.194   21.138  1.00 31.44  ? 98  THR C CB  1 
ATOM   7931  O OG1 . THR C 1 98  ? 29.204  4.261   20.447  1.00 31.40  ? 98  THR C OG1 1 
ATOM   7932  C CG2 . THR C 1 98  ? 27.100  4.520   21.582  1.00 34.98  ? 98  THR C CG2 1 
ATOM   7933  N N   . GLY C 1 99  ? 30.202  6.538   18.802  1.00 38.22  ? 99  GLY C N   1 
ATOM   7934  C CA  . GLY C 1 99  ? 31.592  6.881   18.578  1.00 35.66  ? 99  GLY C CA  1 
ATOM   7935  C C   . GLY C 1 99  ? 32.541  5.934   19.310  1.00 34.87  ? 99  GLY C C   1 
ATOM   7936  O O   . GLY C 1 99  ? 33.756  6.046   19.192  1.00 38.98  ? 99  GLY C O   1 
ATOM   7937  N N   . GLU C 1 100 ? 31.981  4.921   19.962  1.00 34.63  ? 100 GLU C N   1 
ATOM   7938  C CA  . GLU C 1 100 ? 32.740  3.975   20.752  1.00 36.20  ? 100 GLU C CA  1 
ATOM   7939  C C   . GLU C 1 100 ? 32.565  2.559   20.239  1.00 36.15  ? 100 GLU C C   1 
ATOM   7940  O O   . GLU C 1 100 ? 31.488  2.178   19.751  1.00 35.60  ? 100 GLU C O   1 
ATOM   7941  C CB  . GLU C 1 100 ? 32.248  4.021   22.204  1.00 41.04  ? 100 GLU C CB  1 
ATOM   7942  C CG  . GLU C 1 100 ? 32.486  5.373   22.848  1.00 44.15  ? 100 GLU C CG  1 
ATOM   7943  C CD  . GLU C 1 100 ? 31.820  5.574   24.205  1.00 51.98  ? 100 GLU C CD  1 
ATOM   7944  O OE1 . GLU C 1 100 ? 31.885  6.700   24.703  1.00 54.38  ? 100 GLU C OE1 1 
ATOM   7945  O OE2 . GLU C 1 100 ? 31.207  4.608   24.735  1.00 52.83  ? 100 GLU C OE2 1 
ATOM   7946  N N   . LEU C 1 101 ? 33.630  1.771   20.411  1.00 32.74  ? 101 LEU C N   1 
ATOM   7947  C CA  . LEU C 1 101 ? 33.665  0.400   19.937  1.00 32.60  ? 101 LEU C CA  1 
ATOM   7948  C C   . LEU C 1 101 ? 32.854  -0.459  20.882  1.00 39.14  ? 101 LEU C C   1 
ATOM   7949  O O   . LEU C 1 101 ? 32.955  -0.340  22.092  1.00 37.78  ? 101 LEU C O   1 
ATOM   7950  C CB  . LEU C 1 101 ? 35.104  -0.127  19.859  1.00 33.79  ? 101 LEU C CB  1 
ATOM   7951  C CG  . LEU C 1 101 ? 36.002  0.554   18.821  1.00 38.21  ? 101 LEU C CG  1 
ATOM   7952  C CD1 . LEU C 1 101 ? 37.466  0.199   19.058  1.00 37.98  ? 101 LEU C CD1 1 
ATOM   7953  C CD2 . LEU C 1 101 ? 35.595  0.166   17.404  1.00 36.11  ? 101 LEU C CD2 1 
ATOM   7954  N N   . PRO C 1 102 ? 32.013  -1.355  20.348  1.00 39.41  ? 102 PRO C N   1 
ATOM   7955  C CA  . PRO C 1 102 ? 31.133  -2.154  21.192  1.00 34.52  ? 102 PRO C CA  1 
ATOM   7956  C C   . PRO C 1 102 ? 31.884  -3.331  21.805  1.00 37.55  ? 102 PRO C C   1 
ATOM   7957  O O   . PRO C 1 102 ? 32.827  -3.831  21.211  1.00 39.52  ? 102 PRO C O   1 
ATOM   7958  C CB  . PRO C 1 102 ? 30.068  -2.617  20.177  1.00 35.44  ? 102 PRO C CB  1 
ATOM   7959  C CG  . PRO C 1 102 ? 30.853  -2.759  18.905  1.00 35.92  ? 102 PRO C CG  1 
ATOM   7960  C CD  . PRO C 1 102 ? 31.810  -1.575  18.910  1.00 37.53  ? 102 PRO C CD  1 
ATOM   7961  N N   . THR C 1 103 ? 31.452  -3.775  22.990  1.00 36.33  ? 103 THR C N   1 
ATOM   7962  C CA  . THR C 1 103 ? 31.882  -5.053  23.532  1.00 37.26  ? 103 THR C CA  1 
ATOM   7963  C C   . THR C 1 103 ? 31.035  -6.147  22.898  1.00 37.23  ? 103 THR C C   1 
ATOM   7964  O O   . THR C 1 103 ? 29.994  -5.852  22.311  1.00 32.96  ? 103 THR C O   1 
ATOM   7965  C CB  . THR C 1 103 ? 31.668  -5.116  25.052  1.00 44.75  ? 103 THR C CB  1 
ATOM   7966  O OG1 . THR C 1 103 ? 30.248  -5.114  25.192  1.00 42.18  ? 103 THR C OG1 1 
ATOM   7967  C CG2 . THR C 1 103 ? 32.287  -3.975  25.837  1.00 41.02  ? 103 THR C CG2 1 
ATOM   7968  N N   . GLU C 1 104 ? 31.440  -7.402  23.094  1.00 37.09  ? 104 GLU C N   1 
ATOM   7969  C CA  . GLU C 1 104 ? 30.675  -8.544  22.633  1.00 42.51  ? 104 GLU C CA  1 
ATOM   7970  C C   . GLU C 1 104 ? 29.236  -8.430  23.129  1.00 45.80  ? 104 GLU C C   1 
ATOM   7971  O O   . GLU C 1 104 ? 28.304  -8.680  22.363  1.00 43.23  ? 104 GLU C O   1 
ATOM   7972  C CB  . GLU C 1 104 ? 31.273  -9.856  23.146  1.00 47.87  ? 104 GLU C CB  1 
ATOM   7973  C CG  . GLU C 1 104 ? 32.590  -10.221 22.501  1.00 53.58  ? 104 GLU C CG  1 
ATOM   7974  C CD  . GLU C 1 104 ? 32.490  -10.755 21.082  1.00 61.03  ? 104 GLU C CD  1 
ATOM   7975  O OE1 . GLU C 1 104 ? 33.534  -10.808 20.414  1.00 64.52  ? 104 GLU C OE1 1 
ATOM   7976  O OE2 . GLU C 1 104 ? 31.383  -11.164 20.667  1.00 58.61  ? 104 GLU C OE2 1 
ATOM   7977  N N   . GLU C 1 105 ? 29.052  -8.045  24.406  1.00 45.51  ? 105 GLU C N   1 
ATOM   7978  C CA  . GLU C 1 105 ? 27.722  -8.087  24.976  1.00 47.11  ? 105 GLU C CA  1 
ATOM   7979  C C   . GLU C 1 105 ? 26.876  -6.943  24.434  1.00 40.62  ? 105 GLU C C   1 
ATOM   7980  O O   . GLU C 1 105 ? 25.664  -7.096  24.333  1.00 38.51  ? 105 GLU C O   1 
ATOM   7981  C CB  . GLU C 1 105 ? 27.656  -8.062  26.507  1.00 58.61  ? 105 GLU C CB  1 
ATOM   7982  C CG  . GLU C 1 105 ? 26.435  -8.849  26.990  1.00 65.01  ? 105 GLU C CG  1 
ATOM   7983  C CD  . GLU C 1 105 ? 25.622  -8.272  28.134  1.00 82.48  ? 105 GLU C CD  1 
ATOM   7984  O OE1 . GLU C 1 105 ? 24.426  -7.935  27.911  1.00 80.49  ? 105 GLU C OE1 1 
ATOM   7985  O OE2 . GLU C 1 105 ? 26.159  -8.209  29.257  1.00 97.80  ? 105 GLU C OE2 1 
ATOM   7986  N N   . ASP C 1 106 ? 27.477  -5.782  24.156  1.00 37.85  ? 106 ASP C N   1 
ATOM   7987  C CA  . ASP C 1 106 ? 26.736  -4.696  23.532  1.00 37.03  ? 106 ASP C CA  1 
ATOM   7988  C C   . ASP C 1 106 ? 26.076  -5.200  22.245  1.00 39.97  ? 106 ASP C C   1 
ATOM   7989  O O   . ASP C 1 106 ? 24.923  -4.878  21.980  1.00 41.19  ? 106 ASP C O   1 
ATOM   7990  C CB  . ASP C 1 106 ? 27.607  -3.477  23.228  1.00 39.57  ? 106 ASP C CB  1 
ATOM   7991  C CG  . ASP C 1 106 ? 28.271  -2.840  24.448  1.00 47.69  ? 106 ASP C CG  1 
ATOM   7992  O OD1 . ASP C 1 106 ? 27.768  -3.092  25.562  1.00 54.80  ? 106 ASP C OD1 1 
ATOM   7993  O OD2 . ASP C 1 106 ? 29.317  -2.112  24.275  1.00 40.07  ? 106 ASP C OD2 1 
ATOM   7994  N N   . VAL C 1 107 ? 26.804  -6.004  21.462  1.00 35.12  ? 107 VAL C N   1 
ATOM   7995  C CA  . VAL C 1 107 ? 26.333  -6.454  20.163  1.00 40.13  ? 107 VAL C CA  1 
ATOM   7996  C C   . VAL C 1 107 ? 25.226  -7.488  20.364  1.00 40.27  ? 107 VAL C C   1 
ATOM   7997  O O   . VAL C 1 107 ? 24.188  -7.455  19.705  1.00 39.32  ? 107 VAL C O   1 
ATOM   7998  C CB  . VAL C 1 107 ? 27.511  -6.977  19.315  1.00 38.74  ? 107 VAL C CB  1 
ATOM   7999  C CG1 . VAL C 1 107 ? 27.071  -7.743  18.079  1.00 40.14  ? 107 VAL C CG1 1 
ATOM   8000  C CG2 . VAL C 1 107 ? 28.425  -5.832  18.927  1.00 40.69  ? 107 VAL C CG2 1 
ATOM   8001  N N   . LYS C 1 108 ? 25.431  -8.413  21.286  1.00 41.46  ? 108 LYS C N   1 
ATOM   8002  C CA  . LYS C 1 108 ? 24.414  -9.402  21.568  1.00 42.72  ? 108 LYS C CA  1 
ATOM   8003  C C   . LYS C 1 108 ? 23.106  -8.727  21.986  1.00 42.03  ? 108 LYS C C   1 
ATOM   8004  O O   . LYS C 1 108 ? 22.041  -9.211  21.600  1.00 39.55  ? 108 LYS C O   1 
ATOM   8005  C CB  . LYS C 1 108 ? 24.950  -10.417 22.577  1.00 50.11  ? 108 LYS C CB  1 
ATOM   8006  C CG  . LYS C 1 108 ? 26.095  -11.263 22.031  1.00 56.26  ? 108 LYS C CG  1 
ATOM   8007  C CD  . LYS C 1 108 ? 26.189  -12.662 22.629  1.00 68.61  ? 108 LYS C CD  1 
ATOM   8008  C CE  . LYS C 1 108 ? 26.760  -12.703 24.034  1.00 78.60  ? 108 LYS C CE  1 
ATOM   8009  N NZ  . LYS C 1 108 ? 28.231  -12.903 24.032  1.00 82.73  ? 108 LYS C NZ  1 
ATOM   8010  N N   . GLU C 1 109 ? 23.172  -7.611  22.732  1.00 38.45  ? 109 GLU C N   1 
ATOM   8011  C CA  . GLU C 1 109 ? 21.961  -6.906  23.129  1.00 40.81  ? 109 GLU C CA  1 
ATOM   8012  C C   . GLU C 1 109 ? 21.249  -6.321  21.901  1.00 39.76  ? 109 GLU C C   1 
ATOM   8013  O O   . GLU C 1 109 ? 20.028  -6.288  21.858  1.00 35.75  ? 109 GLU C O   1 
ATOM   8014  C CB  . GLU C 1 109 ? 22.229  -5.728  24.065  1.00 41.28  ? 109 GLU C CB  1 
ATOM   8015  C CG  . GLU C 1 109 ? 22.469  -6.122  25.514  1.00 51.59  ? 109 GLU C CG  1 
ATOM   8016  C CD  . GLU C 1 109 ? 23.014  -5.031  26.447  1.00 57.06  ? 109 GLU C CD  1 
ATOM   8017  O OE1 . GLU C 1 109 ? 23.425  -5.391  27.569  1.00 66.96  ? 109 GLU C OE1 1 
ATOM   8018  O OE2 . GLU C 1 109 ? 23.048  -3.818  26.078  1.00 53.21  ? 109 GLU C OE2 1 
ATOM   8019  N N   . ILE C 1 110 ? 22.006  -5.743  20.965  1.00 36.94  ? 110 ILE C N   1 
ATOM   8020  C CA  . ILE C 1 110 ? 21.405  -5.144  19.783  1.00 37.72  ? 110 ILE C CA  1 
ATOM   8021  C C   . ILE C 1 110 ? 20.779  -6.259  18.941  1.00 37.73  ? 110 ILE C C   1 
ATOM   8022  O O   . ILE C 1 110 ? 19.648  -6.113  18.499  1.00 40.91  ? 110 ILE C O   1 
ATOM   8023  C CB  . ILE C 1 110 ? 22.414  -4.300  18.992  1.00 36.44  ? 110 ILE C CB  1 
ATOM   8024  C CG1 . ILE C 1 110 ? 22.863  -3.082  19.805  1.00 36.39  ? 110 ILE C CG1 1 
ATOM   8025  C CG2 . ILE C 1 110 ? 21.836  -3.906  17.646  1.00 39.73  ? 110 ILE C CG2 1 
ATOM   8026  C CD1 . ILE C 1 110 ? 24.108  -2.420  19.291  1.00 37.27  ? 110 ILE C CD1 1 
ATOM   8027  N N   . SER C 1 111 ? 21.494  -7.376  18.776  1.00 36.61  ? 111 SER C N   1 
ATOM   8028  C CA  . SER C 1 111 ? 21.024  -8.524  18.031  1.00 38.29  ? 111 SER C CA  1 
ATOM   8029  C C   . SER C 1 111 ? 19.710  -9.066  18.594  1.00 39.63  ? 111 SER C C   1 
ATOM   8030  O O   . SER C 1 111 ? 18.830  -9.381  17.803  1.00 34.80  ? 111 SER C O   1 
ATOM   8031  C CB  . SER C 1 111 ? 22.063  -9.601  17.940  1.00 42.23  ? 111 SER C CB  1 
ATOM   8032  O OG  . SER C 1 111 ? 23.076  -9.208  17.042  1.00 38.18  ? 111 SER C OG  1 
ATOM   8033  N N   . ALA C 1 112 ? 19.568  -9.100  19.926  1.00 35.97  ? 112 ALA C N   1 
ATOM   8034  C CA  . ALA C 1 112 ? 18.371  -9.580  20.591  1.00 41.77  ? 112 ALA C CA  1 
ATOM   8035  C C   . ALA C 1 112 ? 17.214  -8.591  20.422  1.00 42.55  ? 112 ALA C C   1 
ATOM   8036  O O   . ALA C 1 112 ? 16.080  -9.008  20.229  1.00 42.34  ? 112 ALA C O   1 
ATOM   8037  C CB  . ALA C 1 112 ? 18.649  -9.844  22.062  1.00 44.53  ? 112 ALA C CB  1 
ATOM   8038  N N   . GLU C 1 113 ? 17.508  -7.294  20.480  1.00 39.23  ? 113 GLU C N   1 
ATOM   8039  C CA  . GLU C 1 113 ? 16.531  -6.247  20.239  1.00 38.31  ? 113 GLU C CA  1 
ATOM   8040  C C   . GLU C 1 113 ? 15.991  -6.397  18.811  1.00 41.30  ? 113 GLU C C   1 
ATOM   8041  O O   . GLU C 1 113 ? 14.792  -6.376  18.570  1.00 39.18  ? 113 GLU C O   1 
ATOM   8042  C CB  . GLU C 1 113 ? 17.242  -4.919  20.513  1.00 48.15  ? 113 GLU C CB  1 
ATOM   8043  C CG  . GLU C 1 113 ? 16.433  -3.828  21.190  1.00 58.37  ? 113 GLU C CG  1 
ATOM   8044  C CD  . GLU C 1 113 ? 15.599  -4.227  22.397  1.00 54.35  ? 113 GLU C CD  1 
ATOM   8045  O OE1 . GLU C 1 113 ? 14.438  -4.582  22.184  1.00 50.00  ? 113 GLU C OE1 1 
ATOM   8046  O OE2 . GLU C 1 113 ? 16.093  -4.140  23.531  1.00 58.64  ? 113 GLU C OE2 1 
ATOM   8047  N N   . PHE C 1 114 ? 16.864  -6.570  17.825  1.00 34.01  ? 114 PHE C N   1 
ATOM   8048  C CA  . PHE C 1 114 ? 16.366  -6.800  16.484  1.00 41.40  ? 114 PHE C CA  1 
ATOM   8049  C C   . PHE C 1 114 ? 15.503  -8.062  16.425  1.00 46.77  ? 114 PHE C C   1 
ATOM   8050  O O   . PHE C 1 114 ? 14.433  -8.071  15.807  1.00 40.59  ? 114 PHE C O   1 
ATOM   8051  C CB  . PHE C 1 114 ? 17.527  -6.856  15.508  1.00 35.85  ? 114 PHE C CB  1 
ATOM   8052  C CG  . PHE C 1 114 ? 18.213  -5.540  15.309  1.00 38.06  ? 114 PHE C CG  1 
ATOM   8053  C CD1 . PHE C 1 114 ? 17.623  -4.350  15.709  1.00 39.93  ? 114 PHE C CD1 1 
ATOM   8054  C CD2 . PHE C 1 114 ? 19.446  -5.483  14.704  1.00 39.62  ? 114 PHE C CD2 1 
ATOM   8055  C CE1 . PHE C 1 114 ? 18.277  -3.142  15.534  1.00 37.54  ? 114 PHE C CE1 1 
ATOM   8056  C CE2 . PHE C 1 114 ? 20.072  -4.261  14.496  1.00 42.57  ? 114 PHE C CE2 1 
ATOM   8057  C CZ  . PHE C 1 114 ? 19.497  -3.099  14.924  1.00 35.81  ? 114 PHE C CZ  1 
ATOM   8058  N N   . THR C 1 115 ? 15.947  -9.122  17.095  1.00 40.55  ? 115 THR C N   1 
ATOM   8059  C CA  . THR C 1 115 ? 15.303  -10.422 16.982  1.00 42.68  ? 115 THR C CA  1 
ATOM   8060  C C   . THR C 1 115 ? 13.867  -10.372 17.510  1.00 42.49  ? 115 THR C C   1 
ATOM   8061  O O   . THR C 1 115 ? 12.932  -10.837 16.857  1.00 48.57  ? 115 THR C O   1 
ATOM   8062  C CB  . THR C 1 115 ? 16.203  -11.471 17.662  1.00 50.00  ? 115 THR C CB  1 
ATOM   8063  O OG1 . THR C 1 115 ? 17.081  -11.936 16.629  1.00 53.71  ? 115 THR C OG1 1 
ATOM   8064  C CG2 . THR C 1 115 ? 15.442  -12.612 18.313  1.00 48.30  ? 115 THR C CG2 1 
ATOM   8065  N N   . LYS C 1 116 ? 13.707  -9.835  18.714  1.00 39.19  ? 116 LYS C N   1 
ATOM   8066  C CA  . LYS C 1 116 ? 12.408  -9.590  19.292  1.00 41.08  ? 116 LYS C CA  1 
ATOM   8067  C C   . LYS C 1 116 ? 11.558  -8.766  18.311  1.00 40.32  ? 116 LYS C C   1 
ATOM   8068  O O   . LYS C 1 116 ? 10.484  -9.198  17.903  1.00 38.68  ? 116 LYS C O   1 
ATOM   8069  C CB  . LYS C 1 116 ? 12.669  -8.979  20.667  1.00 46.12  ? 116 LYS C CB  1 
ATOM   8070  C CG  . LYS C 1 116 ? 11.468  -8.692  21.557  1.00 58.36  ? 116 LYS C CG  1 
ATOM   8071  C CD  . LYS C 1 116 ? 11.815  -8.832  23.038  1.00 76.43  ? 116 LYS C CD  1 
ATOM   8072  C CE  . LYS C 1 116 ? 11.259  -7.749  23.940  1.00 81.62  ? 116 LYS C CE  1 
ATOM   8073  N NZ  . LYS C 1 116 ? 12.174  -6.582  24.003  1.00 87.36  ? 116 LYS C NZ  1 
ATOM   8074  N N   . ARG C 1 117 ? 12.062  -7.621  17.837  1.00 33.22  ? 117 ARG C N   1 
ATOM   8075  C CA  . ARG C 1 117 ? 11.217  -6.682  17.123  1.00 30.17  ? 117 ARG C CA  1 
ATOM   8076  C C   . ARG C 1 117 ? 10.860  -7.191  15.721  1.00 28.68  ? 117 ARG C C   1 
ATOM   8077  O O   . ARG C 1 117 ? 9.914   -6.717  15.072  1.00 31.57  ? 117 ARG C O   1 
ATOM   8078  C CB  . ARG C 1 117 ? 11.908  -5.327  17.177  1.00 32.56  ? 117 ARG C CB  1 
ATOM   8079  C CG  . ARG C 1 117 ? 11.900  -4.723  18.571  1.00 34.11  ? 117 ARG C CG  1 
ATOM   8080  C CD  . ARG C 1 117 ? 12.789  -3.498  18.588  1.00 37.08  ? 117 ARG C CD  1 
ATOM   8081  N NE  . ARG C 1 117 ? 13.069  -3.131  19.958  1.00 34.81  ? 117 ARG C NE  1 
ATOM   8082  C CZ  . ARG C 1 117 ? 12.485  -2.140  20.618  1.00 37.44  ? 117 ARG C CZ  1 
ATOM   8083  N NH1 . ARG C 1 117 ? 11.596  -1.369  20.030  1.00 35.86  ? 117 ARG C NH1 1 
ATOM   8084  N NH2 . ARG C 1 117 ? 12.800  -1.928  21.879  1.00 39.15  ? 117 ARG C NH2 1 
ATOM   8085  N N   . MET C 1 118 ? 11.638  -8.152  15.231  1.00 30.29  ? 118 MET C N   1 
ATOM   8086  C CA  . MET C 1 118 ? 11.453  -8.715  13.909  1.00 35.61  ? 118 MET C CA  1 
ATOM   8087  C C   . MET C 1 118 ? 10.106  -9.449  13.839  1.00 36.33  ? 118 MET C C   1 
ATOM   8088  O O   . MET C 1 118 ? 9.585   -9.671  12.755  1.00 35.24  ? 118 MET C O   1 
ATOM   8089  C CB  . MET C 1 118 ? 12.595  -9.691  13.595  1.00 36.57  ? 118 MET C CB  1 
ATOM   8090  C CG  . MET C 1 118 ? 12.775  -9.960  12.156  1.00 46.56  ? 118 MET C CG  1 
ATOM   8091  S SD  . MET C 1 118 ? 14.393  -10.706 11.719  1.00 43.70  ? 118 MET C SD  1 
ATOM   8092  C CE  . MET C 1 118 ? 15.498  -9.295  11.813  1.00 50.54  ? 118 MET C CE  1 
ATOM   8093  N N   . GLN C 1 119 ? 9.549   -9.779  15.005  1.00 30.70  ? 119 GLN C N   1 
ATOM   8094  C CA  . GLN C 1 119 ? 8.276   -10.461 15.131  1.00 34.84  ? 119 GLN C CA  1 
ATOM   8095  C C   . GLN C 1 119 ? 7.110   -9.483  15.155  1.00 34.95  ? 119 GLN C C   1 
ATOM   8096  O O   . GLN C 1 119 ? 5.968   -9.906  15.272  1.00 36.67  ? 119 GLN C O   1 
ATOM   8097  C CB  . GLN C 1 119 ? 8.251   -11.241 16.451  1.00 42.57  ? 119 GLN C CB  1 
ATOM   8098  C CG  . GLN C 1 119 ? 9.316   -12.332 16.552  1.00 45.74  ? 119 GLN C CG  1 
ATOM   8099  C CD  . GLN C 1 119 ? 9.033   -13.473 15.601  1.00 51.38  ? 119 GLN C CD  1 
ATOM   8100  O OE1 . GLN C 1 119 ? 7.934   -14.011 15.547  1.00 60.62  ? 119 GLN C OE1 1 
ATOM   8101  N NE2 . GLN C 1 119 ? 10.016  -13.856 14.810  1.00 51.61  ? 119 GLN C NE2 1 
ATOM   8102  N N   . ASN C 1 120 ? 7.382   -8.184  15.112  1.00 30.16  ? 120 ASN C N   1 
ATOM   8103  C CA  . ASN C 1 120 ? 6.360   -7.197  15.359  1.00 32.87  ? 120 ASN C CA  1 
ATOM   8104  C C   . ASN C 1 120 ? 6.066   -6.386  14.109  1.00 30.17  ? 120 ASN C C   1 
ATOM   8105  O O   . ASN C 1 120 ? 5.669   -5.235  14.222  1.00 31.89  ? 120 ASN C O   1 
ATOM   8106  C CB  . ASN C 1 120 ? 6.743   -6.224  16.479  1.00 39.35  ? 120 ASN C CB  1 
ATOM   8107  C CG  . ASN C 1 120 ? 7.010   -6.914  17.803  1.00 42.18  ? 120 ASN C CG  1 
ATOM   8108  O OD1 . ASN C 1 120 ? 7.658   -6.346  18.681  1.00 43.15  ? 120 ASN C OD1 1 
ATOM   8109  N ND2 . ASN C 1 120 ? 6.534   -8.133  17.942  1.00 36.98  ? 120 ASN C ND2 1 
ATOM   8110  N N   . VAL C 1 121 ? 6.245   -6.971  12.930  1.00 27.58  ? 121 VAL C N   1 
ATOM   8111  C CA  . VAL C 1 121 ? 5.863   -6.281  11.721  1.00 27.01  ? 121 VAL C CA  1 
ATOM   8112  C C   . VAL C 1 121 ? 4.351   -6.398  11.583  1.00 27.52  ? 121 VAL C C   1 
ATOM   8113  O O   . VAL C 1 121 ? 3.794   -7.486  11.519  1.00 26.65  ? 121 VAL C O   1 
ATOM   8114  C CB  . VAL C 1 121 ? 6.582   -6.811  10.472  1.00 27.87  ? 121 VAL C CB  1 
ATOM   8115  C CG1 . VAL C 1 121 ? 6.162   -6.031  9.249   1.00 27.46  ? 121 VAL C CG1 1 
ATOM   8116  C CG2 . VAL C 1 121 ? 8.082   -6.722  10.611  1.00 29.18  ? 121 VAL C CG2 1 
ATOM   8117  N N   . PRO C 1 122 ? 3.611   -5.280  11.506  1.00 25.48  ? 122 PRO C N   1 
ATOM   8118  C CA  . PRO C 1 122 ? 2.158   -5.369  11.461  1.00 26.04  ? 122 PRO C CA  1 
ATOM   8119  C C   . PRO C 1 122 ? 1.659   -6.180  10.287  1.00 25.64  ? 122 PRO C C   1 
ATOM   8120  O O   . PRO C 1 122 ? 2.214   -6.111  9.201   1.00 24.96  ? 122 PRO C O   1 
ATOM   8121  C CB  . PRO C 1 122 ? 1.706   -3.905  11.283  1.00 26.89  ? 122 PRO C CB  1 
ATOM   8122  C CG  . PRO C 1 122 ? 2.838   -3.120  11.875  1.00 26.86  ? 122 PRO C CG  1 
ATOM   8123  C CD  . PRO C 1 122 ? 4.097   -3.903  11.537  1.00 27.35  ? 122 PRO C CD  1 
ATOM   8124  N N   . GLN C 1 123 ? 0.534   -6.857  10.484  1.00 23.25  ? 123 GLN C N   1 
ATOM   8125  C CA  . GLN C 1 123 ? -0.065  -7.638  9.419   1.00 26.20  ? 123 GLN C CA  1 
ATOM   8126  C C   . GLN C 1 123 ? -0.528  -6.760  8.244   1.00 26.41  ? 123 GLN C C   1 
ATOM   8127  O O   . GLN C 1 123 ? -0.476  -7.214  7.085   1.00 22.04  ? 123 GLN C O   1 
ATOM   8128  C CB  . GLN C 1 123 ? -1.222  -8.465  9.980   1.00 29.77  ? 123 GLN C CB  1 
ATOM   8129  C CG  . GLN C 1 123 ? -2.043  -9.163  8.908   1.00 35.26  ? 123 GLN C CG  1 
ATOM   8130  C CD  . GLN C 1 123 ? -1.229  -10.208 8.190   1.00 41.32  ? 123 GLN C CD  1 
ATOM   8131  O OE1 . GLN C 1 123 ? -0.543  -11.017 8.819   1.00 43.30  ? 123 GLN C OE1 1 
ATOM   8132  N NE2 . GLN C 1 123 ? -1.280  -10.178 6.866   1.00 40.34  ? 123 GLN C NE2 1 
ATOM   8133  N N   . TYR C 1 124 ? -0.970  -5.520  8.510   1.00 24.07  ? 124 TYR C N   1 
ATOM   8134  C CA  . TYR C 1 124 ? -1.425  -4.647  7.436   1.00 23.14  ? 124 TYR C CA  1 
ATOM   8135  C C   . TYR C 1 124 ? -0.270  -4.252  6.512   1.00 21.92  ? 124 TYR C C   1 
ATOM   8136  O O   . TYR C 1 124 ? -0.508  -3.844  5.375   1.00 22.53  ? 124 TYR C O   1 
ATOM   8137  C CB  . TYR C 1 124 ? -2.130  -3.388  7.968   1.00 25.06  ? 124 TYR C CB  1 
ATOM   8138  C CG  . TYR C 1 124 ? -1.259  -2.465  8.785   1.00 24.35  ? 124 TYR C CG  1 
ATOM   8139  C CD1 . TYR C 1 124 ? -0.404  -1.568  8.190   1.00 27.06  ? 124 TYR C CD1 1 
ATOM   8140  C CD2 . TYR C 1 124 ? -1.362  -2.443  10.159  1.00 25.60  ? 124 TYR C CD2 1 
ATOM   8141  C CE1 . TYR C 1 124 ? 0.423   -0.754  8.937   1.00 26.71  ? 124 TYR C CE1 1 
ATOM   8142  C CE2 . TYR C 1 124 ? -0.549  -1.648  10.921  1.00 24.75  ? 124 TYR C CE2 1 
ATOM   8143  C CZ  . TYR C 1 124 ? 0.353   -0.813  10.310  1.00 27.50  ? 124 TYR C CZ  1 
ATOM   8144  O OH  . TYR C 1 124 ? 1.138   0.004   11.032  1.00 29.14  ? 124 TYR C OH  1 
ATOM   8145  N N   . VAL C 1 125 ? 0.989   -4.326  6.984   1.00 23.26  ? 125 VAL C N   1 
ATOM   8146  C CA  . VAL C 1 125 ? 2.129   -4.066  6.097   1.00 22.16  ? 125 VAL C CA  1 
ATOM   8147  C C   . VAL C 1 125 ? 2.160   -5.103  4.969   1.00 24.94  ? 125 VAL C C   1 
ATOM   8148  O O   . VAL C 1 125 ? 2.365   -4.754  3.809   1.00 27.00  ? 125 VAL C O   1 
ATOM   8149  C CB  . VAL C 1 125 ? 3.457   -3.984  6.856   1.00 23.61  ? 125 VAL C CB  1 
ATOM   8150  C CG1 . VAL C 1 125 ? 4.645   -4.037  5.908   1.00 25.29  ? 125 VAL C CG1 1 
ATOM   8151  C CG2 . VAL C 1 125 ? 3.526   -2.711  7.699   1.00 27.28  ? 125 VAL C CG2 1 
ATOM   8152  N N   . PHE C 1 126 ? 1.881   -6.367  5.292   1.00 25.98  ? 126 PHE C N   1 
ATOM   8153  C CA  . PHE C 1 126 ? 1.822   -7.437  4.301   1.00 26.91  ? 126 PHE C CA  1 
ATOM   8154  C C   . PHE C 1 126 ? 0.612   -7.277  3.384   1.00 26.86  ? 126 PHE C C   1 
ATOM   8155  O O   . PHE C 1 126 ? 0.733   -7.447  2.169   1.00 24.95  ? 126 PHE C O   1 
ATOM   8156  C CB  . PHE C 1 126 ? 1.854   -8.809  4.976   1.00 26.06  ? 126 PHE C CB  1 
ATOM   8157  C CG  . PHE C 1 126 ? 3.090   -9.007  5.804   1.00 30.00  ? 126 PHE C CG  1 
ATOM   8158  C CD1 . PHE C 1 126 ? 4.340   -9.106  5.207   1.00 29.65  ? 126 PHE C CD1 1 
ATOM   8159  C CD2 . PHE C 1 126 ? 3.020   -9.012  7.188   1.00 31.17  ? 126 PHE C CD2 1 
ATOM   8160  C CE1 . PHE C 1 126 ? 5.476   -9.262  5.979   1.00 33.90  ? 126 PHE C CE1 1 
ATOM   8161  C CE2 . PHE C 1 126 ? 4.158   -9.173  7.958   1.00 35.36  ? 126 PHE C CE2 1 
ATOM   8162  C CZ  . PHE C 1 126 ? 5.389   -9.293  7.351   1.00 36.09  ? 126 PHE C CZ  1 
ATOM   8163  N N   . ASP C 1 127 ? -0.521  -6.830  3.923   1.00 25.06  ? 127 ASP C N   1 
ATOM   8164  C CA  . ASP C 1 127 ? -1.679  -6.545  3.097   1.00 25.63  ? 127 ASP C CA  1 
ATOM   8165  C C   . ASP C 1 127 ? -1.354  -5.458  2.067   1.00 25.47  ? 127 ASP C C   1 
ATOM   8166  O O   . ASP C 1 127 ? -1.783  -5.522  0.917   1.00 24.55  ? 127 ASP C O   1 
ATOM   8167  C CB  . ASP C 1 127 ? -2.850  -6.048  3.964   1.00 29.52  ? 127 ASP C CB  1 
ATOM   8168  C CG  . ASP C 1 127 ? -3.342  -7.035  5.011   1.00 32.87  ? 127 ASP C CG  1 
ATOM   8169  O OD1 . ASP C 1 127 ? -2.969  -8.249  4.897   1.00 33.09  ? 127 ASP C OD1 1 
ATOM   8170  O OD2 . ASP C 1 127 ? -4.071  -6.572  5.948   1.00 32.74  ? 127 ASP C OD2 1 
ATOM   8171  N N   . VAL C 1 128 ? -0.682  -4.394  2.507   1.00 23.21  ? 128 VAL C N   1 
ATOM   8172  C CA  . VAL C 1 128 ? -0.282  -3.320  1.603   1.00 22.00  ? 128 VAL C CA  1 
ATOM   8173  C C   . VAL C 1 128 ? 0.640   -3.875  0.522   1.00 23.41  ? 128 VAL C C   1 
ATOM   8174  O O   . VAL C 1 128 ? 0.462   -3.593  -0.661  1.00 26.15  ? 128 VAL C O   1 
ATOM   8175  C CB  . VAL C 1 128 ? 0.412   -2.166  2.352   1.00 24.46  ? 128 VAL C CB  1 
ATOM   8176  C CG1 . VAL C 1 128 ? 1.115   -1.234  1.393   1.00 26.13  ? 128 VAL C CG1 1 
ATOM   8177  C CG2 . VAL C 1 128 ? -0.567  -1.383  3.198   1.00 24.59  ? 128 VAL C CG2 1 
ATOM   8178  N N   . LEU C 1 129 ? 1.611   -4.693  0.907   1.00 25.60  ? 129 LEU C N   1 
ATOM   8179  C CA  . LEU C 1 129 ? 2.554   -5.244  -0.066  1.00 25.64  ? 129 LEU C CA  1 
ATOM   8180  C C   . LEU C 1 129 ? 1.840   -6.170  -1.041  1.00 27.05  ? 129 LEU C C   1 
ATOM   8181  O O   . LEU C 1 129 ? 2.169   -6.149  -2.229  1.00 27.62  ? 129 LEU C O   1 
ATOM   8182  C CB  . LEU C 1 129 ? 3.659   -6.041  0.627   1.00 24.52  ? 129 LEU C CB  1 
ATOM   8183  C CG  . LEU C 1 129 ? 4.693   -5.229  1.388   1.00 24.94  ? 129 LEU C CG  1 
ATOM   8184  C CD1 . LEU C 1 129 ? 5.542   -6.142  2.204   1.00 28.12  ? 129 LEU C CD1 1 
ATOM   8185  C CD2 . LEU C 1 129 ? 5.550   -4.428  0.422   1.00 27.67  ? 129 LEU C CD2 1 
ATOM   8186  N N   . ARG C 1 130 ? 0.889   -6.985  -0.555  1.00 26.26  ? 130 ARG C N   1 
ATOM   8187  C CA  . ARG C 1 130 ? 0.164   -7.906  -1.425  1.00 25.71  ? 130 ARG C CA  1 
ATOM   8188  C C   . ARG C 1 130 ? -0.789  -7.173  -2.362  1.00 25.59  ? 130 ARG C C   1 
ATOM   8189  O O   . ARG C 1 130 ? -1.083  -7.708  -3.412  1.00 24.47  ? 130 ARG C O   1 
ATOM   8190  C CB  . ARG C 1 130 ? -0.666  -8.976  -0.709  1.00 28.85  ? 130 ARG C CB  1 
ATOM   8191  C CG  . ARG C 1 130 ? 0.141   -10.121 -0.123  1.00 36.20  ? 130 ARG C CG  1 
ATOM   8192  C CD  . ARG C 1 130 ? -0.673  -11.367 0.241   1.00 29.90  ? 130 ARG C CD  1 
ATOM   8193  N NE  . ARG C 1 130 ? -0.845  -12.246 -0.915  1.00 28.50  ? 130 ARG C NE  1 
ATOM   8194  C CZ  . ARG C 1 130 ? 0.105   -13.028 -1.453  1.00 31.36  ? 130 ARG C CZ  1 
ATOM   8195  N NH1 . ARG C 1 130 ? -0.231  -13.915 -2.381  1.00 31.90  ? 130 ARG C NH1 1 
ATOM   8196  N NH2 . ARG C 1 130 ? 1.374   -12.947 -1.055  1.00 29.81  ? 130 ARG C NH2 1 
ATOM   8197  N N   . ALA C 1 131 ? -1.242  -5.951  -2.005  1.00 25.61  ? 131 ALA C N   1 
ATOM   8198  C CA  . ALA C 1 131 ? -2.170  -5.193  -2.832  1.00 26.14  ? 131 ALA C CA  1 
ATOM   8199  C C   . ALA C 1 131 ? -1.472  -4.569  -4.043  1.00 26.58  ? 131 ALA C C   1 
ATOM   8200  O O   . ALA C 1 131 ? -2.120  -4.174  -5.006  1.00 26.57  ? 131 ALA C O   1 
ATOM   8201  C CB  . ALA C 1 131 ? -2.765  -4.094  -2.001  1.00 27.60  ? 131 ALA C CB  1 
ATOM   8202  N N   . MET C 1 132 ? -0.152  -4.416  -3.957  1.00 23.64  ? 132 MET C N   1 
ATOM   8203  C CA  . MET C 1 132 ? 0.630   -3.927  -5.082  1.00 27.90  ? 132 MET C CA  1 
ATOM   8204  C C   . MET C 1 132 ? 0.817   -5.057  -6.094  1.00 26.80  ? 132 MET C C   1 
ATOM   8205  O O   . MET C 1 132 ? 1.118   -6.194  -5.700  1.00 27.11  ? 132 MET C O   1 
ATOM   8206  C CB  . MET C 1 132 ? 2.000   -3.470  -4.594  1.00 25.92  ? 132 MET C CB  1 
ATOM   8207  C CG  . MET C 1 132 ? 1.936   -2.204  -3.784  1.00 30.10  ? 132 MET C CG  1 
ATOM   8208  S SD  . MET C 1 132 ? 3.560   -1.856  -2.998  1.00 35.04  ? 132 MET C SD  1 
ATOM   8209  C CE  . MET C 1 132 ? 3.971   -0.487  -4.046  1.00 31.62  ? 132 MET C CE  1 
ATOM   8210  N N   . PRO C 1 133 ? 0.646   -4.802  -7.406  1.00 24.13  ? 133 PRO C N   1 
ATOM   8211  C CA  . PRO C 1 133 ? 0.873   -5.829  -8.419  1.00 24.08  ? 133 PRO C CA  1 
ATOM   8212  C C   . PRO C 1 133 ? 2.292   -6.368  -8.319  1.00 23.78  ? 133 PRO C C   1 
ATOM   8213  O O   . PRO C 1 133 ? 3.241   -5.618  -8.132  1.00 25.58  ? 133 PRO C O   1 
ATOM   8214  C CB  . PRO C 1 133 ? 0.726   -5.070  -9.745  1.00 27.43  ? 133 PRO C CB  1 
ATOM   8215  C CG  . PRO C 1 133 ? -0.147  -3.899  -9.390  1.00 27.98  ? 133 PRO C CG  1 
ATOM   8216  C CD  . PRO C 1 133 ? 0.287   -3.513  -7.999  1.00 25.85  ? 133 PRO C CD  1 
ATOM   8217  N N   . VAL C 1 134 ? 2.432   -7.669  -8.550  1.00 26.24  ? 134 VAL C N   1 
ATOM   8218  C CA  . VAL C 1 134 ? 3.664   -8.375  -8.283  1.00 24.79  ? 134 VAL C CA  1 
ATOM   8219  C C   . VAL C 1 134 ? 4.774   -7.914  -9.213  1.00 24.51  ? 134 VAL C C   1 
ATOM   8220  O O   . VAL C 1 134 ? 5.936   -8.137  -8.878  1.00 23.95  ? 134 VAL C O   1 
ATOM   8221  C CB  . VAL C 1 134 ? 3.477   -9.905  -8.381  1.00 28.82  ? 134 VAL C CB  1 
ATOM   8222  C CG1 . VAL C 1 134 ? 3.283   -10.388 -9.807  1.00 29.31  ? 134 VAL C CG1 1 
ATOM   8223  C CG2 . VAL C 1 134 ? 4.644   -10.625 -7.746  1.00 30.41  ? 134 VAL C CG2 1 
ATOM   8224  N N   . ASP C 1 135 ? 4.422   -7.324  -10.368 1.00 24.13  ? 135 ASP C N   1 
ATOM   8225  C CA  . ASP C 1 135 ? 5.420   -6.805  -11.294 1.00 25.95  ? 135 ASP C CA  1 
ATOM   8226  C C   . ASP C 1 135 ? 5.890   -5.383  -10.933 1.00 27.44  ? 135 ASP C C   1 
ATOM   8227  O O   . ASP C 1 135 ? 6.727   -4.820  -11.623 1.00 26.30  ? 135 ASP C O   1 
ATOM   8228  C CB  . ASP C 1 135 ? 4.896   -6.891  -12.728 1.00 26.63  ? 135 ASP C CB  1 
ATOM   8229  C CG  . ASP C 1 135 ? 3.657   -6.042  -12.950 1.00 30.10  ? 135 ASP C CG  1 
ATOM   8230  O OD1 . ASP C 1 135 ? 3.144   -5.435  -11.974 1.00 31.61  ? 135 ASP C OD1 1 
ATOM   8231  O OD2 . ASP C 1 135 ? 3.213   -5.979  -14.079 1.00 31.57  ? 135 ASP C OD2 1 
ATOM   8232  N N   . THR C 1 136 ? 5.444   -4.809  -9.809  1.00 25.54  ? 136 THR C N   1 
ATOM   8233  C CA  . THR C 1 136 ? 5.959   -3.516  -9.359  1.00 26.29  ? 136 THR C CA  1 
ATOM   8234  C C   . THR C 1 136 ? 7.454   -3.645  -9.065  1.00 26.41  ? 136 THR C C   1 
ATOM   8235  O O   . THR C 1 136 ? 7.921   -4.667  -8.569  1.00 25.51  ? 136 THR C O   1 
ATOM   8236  C CB  . THR C 1 136 ? 5.167   -3.054  -8.120  1.00 26.12  ? 136 THR C CB  1 
ATOM   8237  O OG1 . THR C 1 136 ? 3.781   -2.939  -8.467  1.00 24.57  ? 136 THR C OG1 1 
ATOM   8238  C CG2 . THR C 1 136 ? 5.617   -1.716  -7.576  1.00 27.38  ? 136 THR C CG2 1 
ATOM   8239  N N   . HIS C 1 137 ? 8.209   -2.589  -9.349  1.00 26.15  ? 137 HIS C N   1 
ATOM   8240  C CA  . HIS C 1 137 ? 9.616   -2.569  -9.008  1.00 25.23  ? 137 HIS C CA  1 
ATOM   8241  C C   . HIS C 1 137 ? 9.833   -2.852  -7.521  1.00 23.25  ? 137 HIS C C   1 
ATOM   8242  O O   . HIS C 1 137 ? 9.142   -2.340  -6.639  1.00 23.98  ? 137 HIS C O   1 
ATOM   8243  C CB  . HIS C 1 137 ? 10.229  -1.258  -9.520  1.00 27.90  ? 137 HIS C CB  1 
ATOM   8244  C CG  . HIS C 1 137 ? 11.709  -1.267  -9.505  1.00 29.10  ? 137 HIS C CG  1 
ATOM   8245  N ND1 . HIS C 1 137 ? 12.426  -1.197  -8.322  1.00 28.13  ? 137 HIS C ND1 1 
ATOM   8246  C CD2 . HIS C 1 137 ? 12.610  -1.407  -10.513 1.00 29.55  ? 137 HIS C CD2 1 
ATOM   8247  C CE1 . HIS C 1 137 ? 13.732  -1.303  -8.610  1.00 30.39  ? 137 HIS C CE1 1 
ATOM   8248  N NE2 . HIS C 1 137 ? 13.869  -1.419  -9.929  1.00 28.57  ? 137 HIS C NE2 1 
ATOM   8249  N N   . PRO C 1 138 ? 10.814  -3.682  -7.153  1.00 21.62  ? 138 PRO C N   1 
ATOM   8250  C CA  . PRO C 1 138 ? 10.970  -4.056  -5.759  1.00 22.47  ? 138 PRO C CA  1 
ATOM   8251  C C   . PRO C 1 138 ? 11.310  -2.893  -4.827  1.00 21.96  ? 138 PRO C C   1 
ATOM   8252  O O   . PRO C 1 138 ? 11.026  -2.960  -3.632  1.00 23.21  ? 138 PRO C O   1 
ATOM   8253  C CB  . PRO C 1 138 ? 12.090  -5.109  -5.789  1.00 24.03  ? 138 PRO C CB  1 
ATOM   8254  C CG  . PRO C 1 138 ? 12.819  -4.901  -7.075  1.00 23.49  ? 138 PRO C CG  1 
ATOM   8255  C CD  . PRO C 1 138 ? 11.783  -4.355  -8.038  1.00 24.43  ? 138 PRO C CD  1 
ATOM   8256  N N   . MET C 1 139 ? 11.884  -1.819  -5.369  1.00 23.18  ? 139 MET C N   1 
ATOM   8257  C CA  . MET C 1 139 ? 12.215  -0.658  -4.554  1.00 24.02  ? 139 MET C CA  1 
ATOM   8258  C C   . MET C 1 139 ? 10.955  0.165   -4.277  1.00 24.85  ? 139 MET C C   1 
ATOM   8259  O O   . MET C 1 139 ? 10.887  0.847   -3.264  1.00 24.73  ? 139 MET C O   1 
ATOM   8260  C CB  . MET C 1 139 ? 13.264  0.218   -5.233  1.00 23.02  ? 139 MET C CB  1 
ATOM   8261  C CG  . MET C 1 139 ? 14.677  -0.295  -5.024  1.00 26.05  ? 139 MET C CG  1 
ATOM   8262  S SD  . MET C 1 139 ? 15.237  -0.266  -3.296  1.00 26.84  ? 139 MET C SD  1 
ATOM   8263  C CE  . MET C 1 139 ? 15.299  1.493   -2.984  1.00 28.96  ? 139 MET C CE  1 
ATOM   8264  N N   . THR C 1 140 ? 9.986   0.149   -5.199  1.00 23.48  ? 140 THR C N   1 
ATOM   8265  C CA  . THR C 1 140 ? 8.700   0.793   -4.968  1.00 24.40  ? 140 THR C CA  1 
ATOM   8266  C C   . THR C 1 140 ? 7.945   0.036   -3.863  1.00 23.53  ? 140 THR C C   1 
ATOM   8267  O O   . THR C 1 140 ? 7.373   0.651   -2.965  1.00 23.38  ? 140 THR C O   1 
ATOM   8268  C CB  . THR C 1 140 ? 7.887   0.843   -6.260  1.00 23.55  ? 140 THR C CB  1 
ATOM   8269  O OG1 . THR C 1 140 ? 8.647   1.600   -7.194  1.00 25.76  ? 140 THR C OG1 1 
ATOM   8270  C CG2 . THR C 1 140 ? 6.496   1.405   -6.092  1.00 25.24  ? 140 THR C CG2 1 
ATOM   8271  N N   . MET C 1 141 ? 7.947   -1.300  -3.912  1.00 23.56  ? 141 MET C N   1 
ATOM   8272  C CA  . MET C 1 141 ? 7.321   -2.095  -2.866  1.00 24.44  ? 141 MET C CA  1 
ATOM   8273  C C   . MET C 1 141 ? 8.028   -1.869  -1.523  1.00 26.38  ? 141 MET C C   1 
ATOM   8274  O O   . MET C 1 141 ? 7.382   -1.783  -0.488  1.00 24.76  ? 141 MET C O   1 
ATOM   8275  C CB  . MET C 1 141 ? 7.390   -3.584  -3.170  1.00 24.88  ? 141 MET C CB  1 
ATOM   8276  C CG  . MET C 1 141 ? 6.638   -4.039  -4.384  1.00 23.96  ? 141 MET C CG  1 
ATOM   8277  S SD  . MET C 1 141 ? 6.914   -5.843  -4.554  1.00 28.72  ? 141 MET C SD  1 
ATOM   8278  C CE  . MET C 1 141 ? 5.903   -6.068  -6.014  1.00 30.56  ? 141 MET C CE  1 
ATOM   8279  N N   . PHE C 1 142 ? 9.365   -1.775  -1.532  1.00 23.56  ? 142 PHE C N   1 
ATOM   8280  C CA  . PHE C 1 142 ? 10.118  -1.600  -0.316  1.00 22.82  ? 142 PHE C CA  1 
ATOM   8281  C C   . PHE C 1 142 ? 9.761   -0.275  0.361   1.00 25.93  ? 142 PHE C C   1 
ATOM   8282  O O   . PHE C 1 142 ? 9.479   -0.262  1.575   1.00 21.91  ? 142 PHE C O   1 
ATOM   8283  C CB  . PHE C 1 142 ? 11.601  -1.779  -0.619  1.00 25.19  ? 142 PHE C CB  1 
ATOM   8284  C CG  . PHE C 1 142 ? 12.532  -1.787  0.565   1.00 21.43  ? 142 PHE C CG  1 
ATOM   8285  C CD1 . PHE C 1 142 ? 12.372  -2.683  1.607   1.00 23.74  ? 142 PHE C CD1 1 
ATOM   8286  C CD2 . PHE C 1 142 ? 13.622  -0.924  0.587   1.00 22.40  ? 142 PHE C CD2 1 
ATOM   8287  C CE1 . PHE C 1 142 ? 13.284  -2.734  2.652   1.00 23.69  ? 142 PHE C CE1 1 
ATOM   8288  C CE2 . PHE C 1 142 ? 14.519  -0.960  1.647   1.00 24.22  ? 142 PHE C CE2 1 
ATOM   8289  C CZ  . PHE C 1 142 ? 14.349  -1.874  2.670   1.00 24.78  ? 142 PHE C CZ  1 
ATOM   8290  N N   . ALA C 1 143 ? 9.782   0.809   -0.416  1.00 23.39  ? 143 ALA C N   1 
ATOM   8291  C CA  . ALA C 1 143 ? 9.473   2.121   0.122   1.00 27.04  ? 143 ALA C CA  1 
ATOM   8292  C C   . ALA C 1 143 ? 8.033   2.149   0.634   1.00 25.05  ? 143 ALA C C   1 
ATOM   8293  O O   . ALA C 1 143 ? 7.765   2.718   1.688   1.00 25.34  ? 143 ALA C O   1 
ATOM   8294  C CB  . ALA C 1 143 ? 9.758   3.195   -0.880  1.00 26.14  ? 143 ALA C CB  1 
ATOM   8295  N N   . ALA C 1 144 ? 7.108   1.509   -0.087  1.00 24.22  ? 144 ALA C N   1 
ATOM   8296  C CA  . ALA C 1 144 ? 5.701   1.501   0.290   1.00 23.77  ? 144 ALA C CA  1 
ATOM   8297  C C   . ALA C 1 144 ? 5.460   0.754   1.597   1.00 23.34  ? 144 ALA C C   1 
ATOM   8298  O O   . ALA C 1 144 ? 4.657   1.192   2.429   1.00 24.49  ? 144 ALA C O   1 
ATOM   8299  C CB  . ALA C 1 144 ? 4.877   0.912   -0.823  1.00 25.01  ? 144 ALA C CB  1 
ATOM   8300  N N   . GLY C 1 145 ? 6.136   -0.384  1.787   1.00 23.38  ? 145 GLY C N   1 
ATOM   8301  C CA  . GLY C 1 145 ? 6.012   -1.184  3.000   1.00 24.26  ? 145 GLY C CA  1 
ATOM   8302  C C   . GLY C 1 145 ? 6.489   -0.415  4.235   1.00 27.58  ? 145 GLY C C   1 
ATOM   8303  O O   . GLY C 1 145 ? 5.879   -0.444  5.307   1.00 27.42  ? 145 GLY C O   1 
ATOM   8304  N N   . ILE C 1 146 ? 7.627   0.249   4.081   1.00 23.92  ? 146 ILE C N   1 
ATOM   8305  C CA  . ILE C 1 146 ? 8.202   1.062   5.131   1.00 22.57  ? 146 ILE C CA  1 
ATOM   8306  C C   . ILE C 1 146 ? 7.256   2.196   5.486   1.00 23.91  ? 146 ILE C C   1 
ATOM   8307  O O   . ILE C 1 146 ? 6.989   2.397   6.660   1.00 25.66  ? 146 ILE C O   1 
ATOM   8308  C CB  . ILE C 1 146 ? 9.566   1.632   4.723   1.00 24.58  ? 146 ILE C CB  1 
ATOM   8309  C CG1 . ILE C 1 146 ? 10.627  0.546   4.561   1.00 26.16  ? 146 ILE C CG1 1 
ATOM   8310  C CG2 . ILE C 1 146 ? 10.050  2.647   5.758   1.00 25.59  ? 146 ILE C CG2 1 
ATOM   8311  C CD1 . ILE C 1 146 ? 11.740  0.989   3.648   1.00 26.04  ? 146 ILE C CD1 1 
ATOM   8312  N N   . LEU C 1 147 ? 6.800   2.937   4.469   1.00 22.88  ? 147 LEU C N   1 
ATOM   8313  C CA  . LEU C 1 147 ? 5.892   4.038   4.709   1.00 26.26  ? 147 LEU C CA  1 
ATOM   8314  C C   . LEU C 1 147 ? 4.627   3.571   5.429   1.00 26.54  ? 147 LEU C C   1 
ATOM   8315  O O   . LEU C 1 147 ? 4.178   4.259   6.330   1.00 25.09  ? 147 LEU C O   1 
ATOM   8316  C CB  . LEU C 1 147 ? 5.580   4.744   3.395   1.00 26.56  ? 147 LEU C CB  1 
ATOM   8317  C CG  . LEU C 1 147 ? 4.581   5.890   3.502   1.00 29.03  ? 147 LEU C CG  1 
ATOM   8318  C CD1 . LEU C 1 147 ? 5.087   6.981   4.446   1.00 28.04  ? 147 LEU C CD1 1 
ATOM   8319  C CD2 . LEU C 1 147 ? 4.329   6.440   2.120   1.00 28.75  ? 147 LEU C CD2 1 
ATOM   8320  N N   . ALA C 1 148 ? 4.073   2.397   5.080   1.00 26.40  ? 148 ALA C N   1 
ATOM   8321  C CA  . ALA C 1 148 ? 2.822   1.956   5.688   1.00 26.58  ? 148 ALA C CA  1 
ATOM   8322  C C   . ALA C 1 148 ? 2.961   1.814   7.207   1.00 26.19  ? 148 ALA C C   1 
ATOM   8323  O O   . ALA C 1 148 ? 2.023   2.100   7.925   1.00 25.43  ? 148 ALA C O   1 
ATOM   8324  C CB  . ALA C 1 148 ? 2.362   0.639   5.100   1.00 27.05  ? 148 ALA C CB  1 
ATOM   8325  N N   . MET C 1 149 ? 4.154   1.418   7.682   1.00 26.20  ? 149 MET C N   1 
ATOM   8326  C CA  . MET C 1 149 ? 4.415   1.199   9.092   1.00 24.98  ? 149 MET C CA  1 
ATOM   8327  C C   . MET C 1 149 ? 4.568   2.501   9.901   1.00 25.86  ? 149 MET C C   1 
ATOM   8328  O O   . MET C 1 149 ? 4.721   2.466   11.128  1.00 26.68  ? 149 MET C O   1 
ATOM   8329  C CB  . MET C 1 149 ? 5.686   0.358   9.179   1.00 27.59  ? 149 MET C CB  1 
ATOM   8330  C CG  . MET C 1 149 ? 5.910   -0.313  10.466  1.00 29.07  ? 149 MET C CG  1 
ATOM   8331  S SD  . MET C 1 149 ? 7.142   -1.664  10.272  1.00 30.72  ? 149 MET C SD  1 
ATOM   8332  C CE  . MET C 1 149 ? 7.313   -2.001  12.031  1.00 29.93  ? 149 MET C CE  1 
ATOM   8333  N N   . GLN C 1 150 ? 4.530   3.659   9.229   1.00 23.72  ? 150 GLN C N   1 
ATOM   8334  C CA  . GLN C 1 150 ? 4.527   4.956   9.886   1.00 23.79  ? 150 GLN C CA  1 
ATOM   8335  C C   . GLN C 1 150 ? 3.426   5.059   10.949  1.00 26.24  ? 150 GLN C C   1 
ATOM   8336  O O   . GLN C 1 150 ? 3.592   5.759   11.940  1.00 25.32  ? 150 GLN C O   1 
ATOM   8337  C CB  . GLN C 1 150 ? 4.340   6.043   8.835   1.00 23.18  ? 150 GLN C CB  1 
ATOM   8338  C CG  . GLN C 1 150 ? 4.436   7.457   9.370   1.00 26.68  ? 150 GLN C CG  1 
ATOM   8339  C CD  . GLN C 1 150 ? 3.164   8.010   9.982   1.00 27.79  ? 150 GLN C CD  1 
ATOM   8340  O OE1 . GLN C 1 150 ? 2.048   7.633   9.621   1.00 26.77  ? 150 GLN C OE1 1 
ATOM   8341  N NE2 . GLN C 1 150 ? 3.342   8.959   10.896  1.00 25.02  ? 150 GLN C NE2 1 
ATOM   8342  N N   . ARG C 1 151 ? 2.309   4.346   10.743  1.00 26.37  ? 151 ARG C N   1 
ATOM   8343  C CA  . ARG C 1 151 ? 1.239   4.261   11.722  1.00 27.05  ? 151 ARG C CA  1 
ATOM   8344  C C   . ARG C 1 151 ? 1.771   3.856   13.094  1.00 27.42  ? 151 ARG C C   1 
ATOM   8345  O O   . ARG C 1 151 ? 1.215   4.257   14.101  1.00 24.84  ? 151 ARG C O   1 
ATOM   8346  C CB  . ARG C 1 151 ? 0.124   3.316   11.221  1.00 29.90  ? 151 ARG C CB  1 
ATOM   8347  C CG  . ARG C 1 151 ? -1.008  3.086   12.226  1.00 33.08  ? 151 ARG C CG  1 
ATOM   8348  C CD  . ARG C 1 151 ? -1.905  1.928   11.811  1.00 40.37  ? 151 ARG C CD  1 
ATOM   8349  N NE  . ARG C 1 151 ? -3.085  1.755   12.660  1.00 37.55  ? 151 ARG C NE  1 
ATOM   8350  C CZ  . ARG C 1 151 ? -3.160  0.951   13.715  1.00 35.02  ? 151 ARG C CZ  1 
ATOM   8351  N NH1 . ARG C 1 151 ? -2.107  0.238   14.112  1.00 33.15  ? 151 ARG C NH1 1 
ATOM   8352  N NH2 . ARG C 1 151 ? -4.281  0.924   14.419  1.00 29.53  ? 151 ARG C NH2 1 
ATOM   8353  N N   . GLU C 1 152 ? 2.830   3.048   13.171  1.00 26.76  ? 152 GLU C N   1 
ATOM   8354  C CA  . GLU C 1 152 ? 3.372   2.665   14.465  1.00 27.43  ? 152 GLU C CA  1 
ATOM   8355  C C   . GLU C 1 152 ? 4.447   3.624   14.992  1.00 28.41  ? 152 GLU C C   1 
ATOM   8356  O O   . GLU C 1 152 ? 5.189   3.228   15.872  1.00 28.87  ? 152 GLU C O   1 
ATOM   8357  C CB  . GLU C 1 152 ? 4.008   1.282   14.352  1.00 27.65  ? 152 GLU C CB  1 
ATOM   8358  C CG  . GLU C 1 152 ? 3.076   0.241   13.712  1.00 33.18  ? 152 GLU C CG  1 
ATOM   8359  C CD  . GLU C 1 152 ? 1.623   0.236   14.181  1.00 34.94  ? 152 GLU C CD  1 
ATOM   8360  O OE1 . GLU C 1 152 ? 0.717   0.069   13.307  1.00 31.26  ? 152 GLU C OE1 1 
ATOM   8361  O OE2 . GLU C 1 152 ? 1.394   0.444   15.390  1.00 34.93  ? 152 GLU C OE2 1 
ATOM   8362  N N   . SER C 1 153 ? 4.618   4.815   14.406  1.00 26.70  ? 153 SER C N   1 
ATOM   8363  C CA  . SER C 1 153 ? 5.689   5.709   14.835  1.00 27.59  ? 153 SER C CA  1 
ATOM   8364  C C   . SER C 1 153 ? 5.453   6.244   16.253  1.00 28.93  ? 153 SER C C   1 
ATOM   8365  O O   . SER C 1 153 ? 4.487   6.954   16.475  1.00 27.94  ? 153 SER C O   1 
ATOM   8366  C CB  . SER C 1 153 ? 5.865   6.879   13.926  1.00 25.20  ? 153 SER C CB  1 
ATOM   8367  O OG  . SER C 1 153 ? 6.908   7.699   14.449  1.00 27.22  ? 153 SER C OG  1 
ATOM   8368  N N   . VAL C 1 154 ? 6.396   5.956   17.153  1.00 29.76  ? 154 VAL C N   1 
ATOM   8369  C CA  . VAL C 1 154 ? 6.449   6.490   18.507  1.00 31.92  ? 154 VAL C CA  1 
ATOM   8370  C C   . VAL C 1 154 ? 6.752   7.987   18.461  1.00 36.58  ? 154 VAL C C   1 
ATOM   8371  O O   . VAL C 1 154 ? 6.210   8.769   19.232  1.00 31.39  ? 154 VAL C O   1 
ATOM   8372  C CB  . VAL C 1 154 ? 7.503   5.688   19.296  1.00 36.01  ? 154 VAL C CB  1 
ATOM   8373  C CG1 . VAL C 1 154 ? 7.879   6.319   20.632  1.00 44.89  ? 154 VAL C CG1 1 
ATOM   8374  C CG2 . VAL C 1 154 ? 7.024   4.253   19.515  1.00 38.93  ? 154 VAL C CG2 1 
ATOM   8375  N N   . PHE C 1 155 ? 7.620   8.405   17.533  1.00 33.59  ? 155 PHE C N   1 
ATOM   8376  C CA  . PHE C 1 155 ? 7.967   9.805   17.426  1.00 30.33  ? 155 PHE C CA  1 
ATOM   8377  C C   . PHE C 1 155 ? 6.739   10.608  17.049  1.00 30.36  ? 155 PHE C C   1 
ATOM   8378  O O   . PHE C 1 155 ? 6.491   11.619  17.690  1.00 33.27  ? 155 PHE C O   1 
ATOM   8379  C CB  . PHE C 1 155 ? 9.153   10.005  16.489  1.00 33.26  ? 155 PHE C CB  1 
ATOM   8380  C CG  . PHE C 1 155 ? 9.618   11.426  16.384  1.00 31.43  ? 155 PHE C CG  1 
ATOM   8381  C CD1 . PHE C 1 155 ? 8.922   12.338  15.633  1.00 28.79  ? 155 PHE C CD1 1 
ATOM   8382  C CD2 . PHE C 1 155 ? 10.731  11.862  17.084  1.00 30.79  ? 155 PHE C CD2 1 
ATOM   8383  C CE1 . PHE C 1 155 ? 9.350   13.659  15.528  1.00 34.06  ? 155 PHE C CE1 1 
ATOM   8384  C CE2 . PHE C 1 155 ? 11.165  13.172  16.955  1.00 32.43  ? 155 PHE C CE2 1 
ATOM   8385  C CZ  . PHE C 1 155 ? 10.492  14.061  16.163  1.00 30.33  ? 155 PHE C CZ  1 
ATOM   8386  N N   . ALA C 1 156 ? 5.992   10.191  16.014  1.00 26.11  ? 156 ALA C N   1 
ATOM   8387  C CA  . ALA C 1 156 ? 4.839   10.945  15.575  1.00 29.44  ? 156 ALA C CA  1 
ATOM   8388  C C   . ALA C 1 156 ? 3.808   11.024  16.708  1.00 30.64  ? 156 ALA C C   1 
ATOM   8389  O O   . ALA C 1 156 ? 3.185   12.057  16.894  1.00 29.05  ? 156 ALA C O   1 
ATOM   8390  C CB  . ALA C 1 156 ? 4.227   10.353  14.322  1.00 32.93  ? 156 ALA C CB  1 
ATOM   8391  N N   . LYS C 1 157 ? 3.659   9.944   17.480  1.00 32.03  ? 157 LYS C N   1 
ATOM   8392  C CA  . LYS C 1 157 ? 2.646   9.900   18.529  1.00 39.19  ? 157 LYS C CA  1 
ATOM   8393  C C   . LYS C 1 157 ? 3.022   10.825  19.695  1.00 34.19  ? 157 LYS C C   1 
ATOM   8394  O O   . LYS C 1 157 ? 2.209   11.626  20.147  1.00 35.48  ? 157 LYS C O   1 
ATOM   8395  C CB  . LYS C 1 157 ? 2.482   8.446   18.988  1.00 40.59  ? 157 LYS C CB  1 
ATOM   8396  C CG  . LYS C 1 157 ? 1.639   8.276   20.242  1.00 51.12  ? 157 LYS C CG  1 
ATOM   8397  C CD  . LYS C 1 157 ? 1.811   6.920   20.931  1.00 63.91  ? 157 LYS C CD  1 
ATOM   8398  C CE  . LYS C 1 157 ? 0.991   5.814   20.294  1.00 74.24  ? 157 LYS C CE  1 
ATOM   8399  N NZ  . LYS C 1 157 ? -0.444  5.911   20.664  1.00 87.61  ? 157 LYS C NZ  1 
ATOM   8400  N N   . ARG C 1 158 ? 4.256   10.696  20.191  1.00 33.07  ? 158 ARG C N   1 
ATOM   8401  C CA  . ARG C 1 158 ? 4.755   11.469  21.325  1.00 38.98  ? 158 ARG C CA  1 
ATOM   8402  C C   . ARG C 1 158 ? 4.823   12.942  20.950  1.00 38.74  ? 158 ARG C C   1 
ATOM   8403  O O   . ARG C 1 158 ? 4.530   13.804  21.764  1.00 40.42  ? 158 ARG C O   1 
ATOM   8404  C CB  . ARG C 1 158 ? 6.137   10.992  21.782  1.00 37.18  ? 158 ARG C CB  1 
ATOM   8405  C CG  . ARG C 1 158 ? 6.159   9.641   22.475  1.00 44.55  ? 158 ARG C CG  1 
ATOM   8406  C CD  . ARG C 1 158 ? 5.404   9.626   23.800  1.00 52.25  ? 158 ARG C CD  1 
ATOM   8407  N NE  . ARG C 1 158 ? 6.022   10.536  24.762  1.00 61.65  ? 158 ARG C NE  1 
ATOM   8408  C CZ  . ARG C 1 158 ? 5.447   11.616  25.289  1.00 57.31  ? 158 ARG C CZ  1 
ATOM   8409  N NH1 . ARG C 1 158 ? 6.144   12.390  26.104  1.00 58.19  ? 158 ARG C NH1 1 
ATOM   8410  N NH2 . ARG C 1 158 ? 4.191   11.922  25.004  1.00 57.73  ? 158 ARG C NH2 1 
ATOM   8411  N N   . TYR C 1 159 ? 5.115   13.239  19.687  1.00 36.58  ? 159 TYR C N   1 
ATOM   8412  C CA  . TYR C 1 159 ? 5.107   14.616  19.252  1.00 36.05  ? 159 TYR C CA  1 
ATOM   8413  C C   . TYR C 1 159 ? 3.716   15.243  19.314  1.00 39.97  ? 159 TYR C C   1 
ATOM   8414  O O   . TYR C 1 159 ? 3.614   16.400  19.718  1.00 38.32  ? 159 TYR C O   1 
ATOM   8415  C CB  . TYR C 1 159 ? 5.607   14.778  17.816  1.00 38.75  ? 159 TYR C CB  1 
ATOM   8416  C CG  . TYR C 1 159 ? 5.819   16.225  17.462  1.00 38.88  ? 159 TYR C CG  1 
ATOM   8417  C CD1 . TYR C 1 159 ? 7.003   16.844  17.803  1.00 42.44  ? 159 TYR C CD1 1 
ATOM   8418  C CD2 . TYR C 1 159 ? 4.816   16.996  16.902  1.00 40.93  ? 159 TYR C CD2 1 
ATOM   8419  C CE1 . TYR C 1 159 ? 7.212   18.183  17.545  1.00 42.54  ? 159 TYR C CE1 1 
ATOM   8420  C CE2 . TYR C 1 159 ? 5.010   18.344  16.636  1.00 43.50  ? 159 TYR C CE2 1 
ATOM   8421  C CZ  . TYR C 1 159 ? 6.221   18.928  16.956  1.00 40.19  ? 159 TYR C CZ  1 
ATOM   8422  O OH  . TYR C 1 159 ? 6.487   20.234  16.699  1.00 56.24  ? 159 TYR C OH  1 
ATOM   8423  N N   . GLU C 1 160 ? 2.671   14.548  18.826  1.00 43.79  ? 160 GLU C N   1 
ATOM   8424  C CA  . GLU C 1 160 ? 1.304   15.071  18.855  1.00 48.56  ? 160 GLU C CA  1 
ATOM   8425  C C   . GLU C 1 160 ? 0.842   15.279  20.298  1.00 40.33  ? 160 GLU C C   1 
ATOM   8426  O O   . GLU C 1 160 ? 0.190   16.275  20.580  1.00 42.20  ? 160 GLU C O   1 
ATOM   8427  C CB  . GLU C 1 160 ? 0.253   14.142  18.237  1.00 51.38  ? 160 GLU C CB  1 
ATOM   8428  C CG  . GLU C 1 160 ? 0.419   13.873  16.758  1.00 69.87  ? 160 GLU C CG  1 
ATOM   8429  C CD  . GLU C 1 160 ? -0.420  14.719  15.814  1.00 80.91  ? 160 GLU C CD  1 
ATOM   8430  O OE1 . GLU C 1 160 ? -1.012  15.722  16.280  1.00 78.64  ? 160 GLU C OE1 1 
ATOM   8431  O OE2 . GLU C 1 160 ? -0.507  14.349  14.611  1.00 86.14  ? 160 GLU C OE2 1 
ATOM   8432  N N   . GLU C 1 161 ? 1.163   14.319  21.178  1.00 41.65  ? 161 GLU C N   1 
ATOM   8433  C CA  . GLU C 1 161 ? 0.812   14.362  22.591  1.00 44.95  ? 161 GLU C CA  1 
ATOM   8434  C C   . GLU C 1 161 ? 1.562   15.460  23.334  1.00 53.82  ? 161 GLU C C   1 
ATOM   8435  O O   . GLU C 1 161 ? 1.146   15.818  24.426  1.00 53.04  ? 161 GLU C O   1 
ATOM   8436  C CB  . GLU C 1 161 ? 1.169   13.067  23.318  1.00 44.52  ? 161 GLU C CB  1 
ATOM   8437  C CG  . GLU C 1 161 ? 0.287   11.896  22.932  1.00 49.01  ? 161 GLU C CG  1 
ATOM   8438  C CD  . GLU C 1 161 ? 0.747   10.519  23.403  1.00 49.83  ? 161 GLU C CD  1 
ATOM   8439  O OE1 . GLU C 1 161 ? -0.027  9.554   23.198  1.00 59.32  ? 161 GLU C OE1 1 
ATOM   8440  O OE2 . GLU C 1 161 ? 1.901   10.392  23.921  1.00 53.98  ? 161 GLU C OE2 1 
ATOM   8441  N N   . GLY C 1 162 ? 2.697   15.925  22.785  1.00 53.93  ? 162 GLY C N   1 
ATOM   8442  C CA  . GLY C 1 162 ? 3.559   16.871  23.475  1.00 48.00  ? 162 GLY C CA  1 
ATOM   8443  C C   . GLY C 1 162 ? 4.727   16.164  24.152  1.00 50.82  ? 162 GLY C C   1 
ATOM   8444  O O   . GLY C 1 162 ? 4.523   15.357  25.055  1.00 66.13  ? 162 GLY C O   1 
ATOM   8445  N N   . MET C 1 163 ? 5.943   16.396  23.655  1.00 42.94  ? 163 MET C N   1 
ATOM   8446  C CA  . MET C 1 163 ? 7.139   15.965  24.355  1.00 43.94  ? 163 MET C CA  1 
ATOM   8447  C C   . MET C 1 163 ? 8.146   17.102  24.254  1.00 42.92  ? 163 MET C C   1 
ATOM   8448  O O   . MET C 1 163 ? 8.096   17.904  23.332  1.00 43.99  ? 163 MET C O   1 
ATOM   8449  C CB  . MET C 1 163 ? 7.761   14.667  23.795  1.00 45.84  ? 163 MET C CB  1 
ATOM   8450  C CG  . MET C 1 163 ? 8.093   14.676  22.294  1.00 42.66  ? 163 MET C CG  1 
ATOM   8451  S SD  . MET C 1 163 ? 9.046   13.204  21.695  1.00 41.46  ? 163 MET C SD  1 
ATOM   8452  C CE  . MET C 1 163 ? 8.830   13.488  19.951  1.00 40.56  ? 163 MET C CE  1 
ATOM   8453  N N   . ARG C 1 164 ? 9.081   17.150  25.188  1.00 51.18  ? 164 ARG C N   1 
ATOM   8454  C CA  . ARG C 1 164 ? 10.150  18.139  25.114  1.00 61.10  ? 164 ARG C CA  1 
ATOM   8455  C C   . ARG C 1 164 ? 11.120  17.735  24.000  1.00 52.74  ? 164 ARG C C   1 
ATOM   8456  O O   . ARG C 1 164 ? 11.220  16.557  23.689  1.00 44.23  ? 164 ARG C O   1 
ATOM   8457  C CB  . ARG C 1 164 ? 10.807  18.234  26.491  1.00 62.18  ? 164 ARG C CB  1 
ATOM   8458  C CG  . ARG C 1 164 ? 9.944   18.940  27.533  1.00 73.36  ? 164 ARG C CG  1 
ATOM   8459  C CD  . ARG C 1 164 ? 10.195  18.457  28.954  1.00 80.57  ? 164 ARG C CD  1 
ATOM   8460  N NE  . ARG C 1 164 ? 11.623  18.322  29.222  1.00 93.95  ? 164 ARG C NE  1 
ATOM   8461  C CZ  . ARG C 1 164 ? 12.282  17.165  29.288  1.00 99.35  ? 164 ARG C CZ  1 
ATOM   8462  N NH1 . ARG C 1 164 ? 11.625  16.017  29.266  1.00 99.48  ? 164 ARG C NH1 1 
ATOM   8463  N NH2 . ARG C 1 164 ? 13.603  17.163  29.376  1.00 97.47  ? 164 ARG C NH2 1 
ATOM   8464  N N   . ARG C 1 165 ? 11.820  18.713  23.410  1.00 53.64  ? 165 ARG C N   1 
ATOM   8465  C CA  . ARG C 1 165 ? 12.738  18.475  22.305  1.00 54.66  ? 165 ARG C CA  1 
ATOM   8466  C C   . ARG C 1 165 ? 13.837  17.504  22.734  1.00 52.94  ? 165 ARG C C   1 
ATOM   8467  O O   . ARG C 1 165 ? 14.452  16.854  21.883  1.00 50.04  ? 165 ARG C O   1 
ATOM   8468  C CB  . ARG C 1 165 ? 13.347  19.783  21.791  1.00 59.35  ? 165 ARG C CB  1 
ATOM   8469  C CG  . ARG C 1 165 ? 12.318  20.804  21.323  1.00 69.52  ? 165 ARG C CG  1 
ATOM   8470  C CD  . ARG C 1 165 ? 12.818  22.238  21.230  1.00 70.39  ? 165 ARG C CD  1 
ATOM   8471  N NE  . ARG C 1 165 ? 13.477  22.458  19.953  1.00 73.93  ? 165 ARG C NE  1 
ATOM   8472  C CZ  . ARG C 1 165 ? 14.695  22.976  19.817  1.00 76.27  ? 165 ARG C CZ  1 
ATOM   8473  N NH1 . ARG C 1 165 ? 15.300  23.519  20.860  1.00 80.58  ? 165 ARG C NH1 1 
ATOM   8474  N NH2 . ARG C 1 165 ? 15.287  22.987  18.633  1.00 56.09  ? 165 ARG C NH2 1 
ATOM   8475  N N   . GLU C 1 166 ? 14.040  17.384  24.052  1.00 46.94  ? 166 GLU C N   1 
ATOM   8476  C CA  . GLU C 1 166 ? 15.106  16.584  24.625  1.00 48.68  ? 166 GLU C CA  1 
ATOM   8477  C C   . GLU C 1 166 ? 14.744  15.099  24.640  1.00 43.65  ? 166 GLU C C   1 
ATOM   8478  O O   . GLU C 1 166 ? 15.601  14.257  24.860  1.00 42.12  ? 166 GLU C O   1 
ATOM   8479  C CB  . GLU C 1 166 ? 15.395  17.048  26.056  1.00 58.24  ? 166 GLU C CB  1 
ATOM   8480  C CG  . GLU C 1 166 ? 16.051  18.427  26.153  1.00 72.83  ? 166 GLU C CG  1 
ATOM   8481  C CD  . GLU C 1 166 ? 15.192  19.671  26.403  1.00 75.19  ? 166 GLU C CD  1 
ATOM   8482  O OE1 . GLU C 1 166 ? 15.777  20.718  26.764  1.00 78.25  ? 166 GLU C OE1 1 
ATOM   8483  O OE2 . GLU C 1 166 ? 13.958  19.629  26.210  1.00 67.92  ? 166 GLU C OE2 1 
ATOM   8484  N N   . GLU C 1 167 ? 13.466  14.763  24.486  1.00 39.84  ? 167 GLU C N   1 
ATOM   8485  C CA  . GLU C 1 167 ? 13.055  13.375  24.364  1.00 38.50  ? 167 GLU C CA  1 
ATOM   8486  C C   . GLU C 1 167 ? 13.089  12.954  22.881  1.00 32.54  ? 167 GLU C C   1 
ATOM   8487  O O   . GLU C 1 167 ? 12.857  11.813  22.560  1.00 32.48  ? 167 GLU C O   1 
ATOM   8488  C CB  . GLU C 1 167 ? 11.649  13.174  24.949  1.00 44.03  ? 167 GLU C CB  1 
ATOM   8489  C CG  . GLU C 1 167 ? 11.370  13.885  26.285  1.00 60.21  ? 167 GLU C CG  1 
ATOM   8490  C CD  . GLU C 1 167 ? 9.912   13.900  26.764  1.00 59.84  ? 167 GLU C CD  1 
ATOM   8491  O OE1 . GLU C 1 167 ? 9.418   12.818  27.158  1.00 68.92  ? 167 GLU C OE1 1 
ATOM   8492  O OE2 . GLU C 1 167 ? 9.242   14.990  26.708  1.00 54.25  ? 167 GLU C OE2 1 
ATOM   8493  N N   . HIS C 1 168 ? 13.326  13.867  21.946  1.00 33.00  ? 168 HIS C N   1 
ATOM   8494  C CA  . HIS C 1 168 ? 13.274  13.526  20.537  1.00 31.78  ? 168 HIS C CA  1 
ATOM   8495  C C   . HIS C 1 168 ? 14.171  12.347  20.181  1.00 35.48  ? 168 HIS C C   1 
ATOM   8496  O O   . HIS C 1 168 ? 13.709  11.421  19.521  1.00 36.23  ? 168 HIS C O   1 
ATOM   8497  C CB  . HIS C 1 168 ? 13.616  14.713  19.656  1.00 29.35  ? 168 HIS C CB  1 
ATOM   8498  C CG  . HIS C 1 168 ? 12.543  15.701  19.579  1.00 30.21  ? 168 HIS C CG  1 
ATOM   8499  N ND1 . HIS C 1 168 ? 12.591  16.738  18.674  1.00 36.31  ? 168 HIS C ND1 1 
ATOM   8500  C CD2 . HIS C 1 168 ? 11.407  15.827  20.270  1.00 33.49  ? 168 HIS C CD2 1 
ATOM   8501  C CE1 . HIS C 1 168 ? 11.483  17.454  18.815  1.00 40.63  ? 168 HIS C CE1 1 
ATOM   8502  N NE2 . HIS C 1 168 ? 10.759  16.904  19.776  1.00 34.87  ? 168 HIS C NE2 1 
ATOM   8503  N N   . TRP C 1 169 ? 15.424  12.336  20.650  1.00 32.67  ? 169 TRP C N   1 
ATOM   8504  C CA  . TRP C 1 169 ? 16.342  11.286  20.251  1.00 34.14  ? 169 TRP C CA  1 
ATOM   8505  C C   . TRP C 1 169 ? 15.861  9.914   20.705  1.00 36.15  ? 169 TRP C C   1 
ATOM   8506  O O   . TRP C 1 169 ? 16.149  8.944   20.042  1.00 32.12  ? 169 TRP C O   1 
ATOM   8507  C CB  . TRP C 1 169 ? 17.778  11.540  20.721  1.00 34.02  ? 169 TRP C CB  1 
ATOM   8508  C CG  . TRP C 1 169 ? 18.034  11.385  22.183  1.00 31.13  ? 169 TRP C CG  1 
ATOM   8509  C CD1 . TRP C 1 169 ? 18.040  12.408  23.095  1.00 35.57  ? 169 TRP C CD1 1 
ATOM   8510  C CD2 . TRP C 1 169 ? 18.345  10.189  22.921  1.00 30.87  ? 169 TRP C CD2 1 
ATOM   8511  N NE1 . TRP C 1 169 ? 18.286  11.926  24.347  1.00 31.04  ? 169 TRP C NE1 1 
ATOM   8512  C CE2 . TRP C 1 169 ? 18.538  10.583  24.267  1.00 30.92  ? 169 TRP C CE2 1 
ATOM   8513  C CE3 . TRP C 1 169 ? 18.520  8.847   22.585  1.00 29.36  ? 169 TRP C CE3 1 
ATOM   8514  C CZ2 . TRP C 1 169 ? 18.854  9.677   25.271  1.00 30.36  ? 169 TRP C CZ2 1 
ATOM   8515  C CZ3 . TRP C 1 169 ? 18.812  7.947   23.577  1.00 32.32  ? 169 TRP C CZ3 1 
ATOM   8516  C CH2 . TRP C 1 169 ? 18.995  8.362   24.902  1.00 33.61  ? 169 TRP C CH2 1 
ATOM   8517  N N   . GLU C 1 170 ? 15.188  9.833   21.858  1.00 34.14  ? 170 GLU C N   1 
ATOM   8518  C CA  . GLU C 1 170 ? 14.777  8.566   22.436  1.00 31.78  ? 170 GLU C CA  1 
ATOM   8519  C C   . GLU C 1 170 ? 13.655  7.927   21.620  1.00 27.82  ? 170 GLU C C   1 
ATOM   8520  O O   . GLU C 1 170 ? 13.575  6.706   21.511  1.00 33.19  ? 170 GLU C O   1 
ATOM   8521  C CB  . GLU C 1 170 ? 14.301  8.794   23.874  1.00 35.87  ? 170 GLU C CB  1 
ATOM   8522  C CG  . GLU C 1 170 ? 15.271  9.651   24.685  1.00 45.31  ? 170 GLU C CG  1 
ATOM   8523  C CD  . GLU C 1 170 ? 15.069  9.660   26.194  1.00 57.22  ? 170 GLU C CD  1 
ATOM   8524  O OE1 . GLU C 1 170 ? 15.641  10.568  26.860  1.00 62.28  ? 170 GLU C OE1 1 
ATOM   8525  O OE2 . GLU C 1 170 ? 14.373  8.743   26.704  1.00 59.55  ? 170 GLU C OE2 1 
ATOM   8526  N N   . ALA C 1 171 ? 12.735  8.762   21.152  1.00 30.12  ? 171 ALA C N   1 
ATOM   8527  C CA  . ALA C 1 171 ? 11.639  8.318   20.311  1.00 32.65  ? 171 ALA C CA  1 
ATOM   8528  C C   . ALA C 1 171 ? 12.196  7.893   18.943  1.00 31.48  ? 171 ALA C C   1 
ATOM   8529  O O   . ALA C 1 171 ? 11.759  6.895   18.406  1.00 31.82  ? 171 ALA C O   1 
ATOM   8530  C CB  . ALA C 1 171 ? 10.646  9.444   20.218  1.00 31.49  ? 171 ALA C CB  1 
ATOM   8531  N N   . MET C 1 172 ? 13.205  8.617   18.426  1.00 31.13  ? 172 MET C N   1 
ATOM   8532  C CA  . MET C 1 172 ? 13.872  8.295   17.171  1.00 30.45  ? 172 MET C CA  1 
ATOM   8533  C C   . MET C 1 172 ? 14.557  6.938   17.276  1.00 30.38  ? 172 MET C C   1 
ATOM   8534  O O   . MET C 1 172 ? 14.571  6.144   16.332  1.00 31.11  ? 172 MET C O   1 
ATOM   8535  C CB  . MET C 1 172 ? 14.922  9.342   16.778  1.00 29.72  ? 172 MET C CB  1 
ATOM   8536  C CG  . MET C 1 172 ? 14.377  10.645  16.266  1.00 30.26  ? 172 MET C CG  1 
ATOM   8537  S SD  . MET C 1 172 ? 13.391  10.557  14.691  1.00 36.21  ? 172 MET C SD  1 
ATOM   8538  C CE  . MET C 1 172 ? 14.408  9.426   13.758  1.00 34.75  ? 172 MET C CE  1 
ATOM   8539  N N   . LEU C 1 173 ? 15.148  6.671   18.432  1.00 30.54  ? 173 LEU C N   1 
ATOM   8540  C CA  . LEU C 1 173 ? 15.864  5.432   18.663  1.00 30.56  ? 173 LEU C CA  1 
ATOM   8541  C C   . LEU C 1 173 ? 14.889  4.256   18.718  1.00 32.07  ? 173 LEU C C   1 
ATOM   8542  O O   . LEU C 1 173 ? 15.172  3.174   18.180  1.00 26.87  ? 173 LEU C O   1 
ATOM   8543  C CB  . LEU C 1 173 ? 16.657  5.520   19.976  1.00 33.46  ? 173 LEU C CB  1 
ATOM   8544  C CG  . LEU C 1 173 ? 17.261  4.201   20.477  1.00 32.58  ? 173 LEU C CG  1 
ATOM   8545  C CD1 . LEU C 1 173 ? 18.260  3.631   19.483  1.00 31.29  ? 173 LEU C CD1 1 
ATOM   8546  C CD2 . LEU C 1 173 ? 17.957  4.381   21.830  1.00 38.26  ? 173 LEU C CD2 1 
ATOM   8547  N N   . GLU C 1 174 ? 13.802  4.428   19.462  1.00 27.31  ? 174 GLU C N   1 
ATOM   8548  C CA  . GLU C 1 174 ? 12.772  3.390   19.535  1.00 29.00  ? 174 GLU C CA  1 
ATOM   8549  C C   . GLU C 1 174 ? 12.233  3.055   18.129  1.00 25.56  ? 174 GLU C C   1 
ATOM   8550  O O   . GLU C 1 174 ? 12.146  1.895   17.716  1.00 24.98  ? 174 GLU C O   1 
ATOM   8551  C CB  . GLU C 1 174 ? 11.679  3.908   20.474  1.00 32.10  ? 174 GLU C CB  1 
ATOM   8552  C CG  . GLU C 1 174 ? 10.574  2.912   20.723  1.00 40.58  ? 174 GLU C CG  1 
ATOM   8553  C CD  . GLU C 1 174 ? 10.975  1.649   21.472  1.00 45.69  ? 174 GLU C CD  1 
ATOM   8554  O OE1 . GLU C 1 174 ? 12.083  1.608   22.109  1.00 44.21  ? 174 GLU C OE1 1 
ATOM   8555  O OE2 . GLU C 1 174 ? 10.176  0.706   21.414  1.00 53.80  ? 174 GLU C OE2 1 
ATOM   8556  N N   . ASP C 1 175 ? 11.890  4.081   17.362  1.00 27.80  ? 175 ASP C N   1 
ATOM   8557  C CA  . ASP C 1 175 ? 11.401  3.884   16.005  1.00 28.31  ? 175 ASP C CA  1 
ATOM   8558  C C   . ASP C 1 175 ? 12.467  3.250   15.108  1.00 29.04  ? 175 ASP C C   1 
ATOM   8559  O O   . ASP C 1 175 ? 12.122  2.486   14.222  1.00 27.67  ? 175 ASP C O   1 
ATOM   8560  C CB  . ASP C 1 175 ? 10.934  5.186   15.381  1.00 28.49  ? 175 ASP C CB  1 
ATOM   8561  C CG  . ASP C 1 175 ? 9.555   5.641   15.817  1.00 31.28  ? 175 ASP C CG  1 
ATOM   8562  O OD1 . ASP C 1 175 ? 8.782   4.767   16.301  1.00 34.26  ? 175 ASP C OD1 1 
ATOM   8563  O OD2 . ASP C 1 175 ? 9.241   6.837   15.597  1.00 28.59  ? 175 ASP C OD2 1 
ATOM   8564  N N   . SER C 1 176 ? 13.742  3.603   15.300  1.00 28.07  ? 176 SER C N   1 
ATOM   8565  C CA  . SER C 1 176 ? 14.835  3.055   14.520  1.00 25.62  ? 176 SER C CA  1 
ATOM   8566  C C   . SER C 1 176 ? 14.969  1.563   14.766  1.00 26.20  ? 176 SER C C   1 
ATOM   8567  O O   . SER C 1 176 ? 15.138  0.804   13.820  1.00 26.75  ? 176 SER C O   1 
ATOM   8568  C CB  . SER C 1 176 ? 16.130  3.795   14.746  1.00 24.04  ? 176 SER C CB  1 
ATOM   8569  O OG  . SER C 1 176 ? 16.024  5.109   14.184  1.00 25.38  ? 176 SER C OG  1 
ATOM   8570  N N   . LEU C 1 177 ? 14.870  1.134   16.020  1.00 27.42  ? 177 LEU C N   1 
ATOM   8571  C CA  . LEU C 1 177 ? 15.006  -0.267  16.363  1.00 27.34  ? 177 LEU C CA  1 
ATOM   8572  C C   . LEU C 1 177 ? 13.892  -1.100  15.709  1.00 29.31  ? 177 LEU C C   1 
ATOM   8573  O O   . LEU C 1 177 ? 14.134  -2.220  15.245  1.00 27.44  ? 177 LEU C O   1 
ATOM   8574  C CB  . LEU C 1 177 ? 14.951  -0.401  17.892  1.00 31.79  ? 177 LEU C CB  1 
ATOM   8575  C CG  . LEU C 1 177 ? 16.174  0.058   18.696  1.00 33.17  ? 177 LEU C CG  1 
ATOM   8576  C CD1 . LEU C 1 177 ? 15.848  -0.028  20.176  1.00 37.79  ? 177 LEU C CD1 1 
ATOM   8577  C CD2 . LEU C 1 177 ? 17.412  -0.812  18.408  1.00 31.86  ? 177 LEU C CD2 1 
ATOM   8578  N N   . ASN C 1 178 ? 12.655  -0.598  15.789  1.00 26.16  ? 178 ASN C N   1 
ATOM   8579  C CA  . ASN C 1 178 ? 11.500  -1.243  15.171  1.00 27.42  ? 178 ASN C CA  1 
ATOM   8580  C C   . ASN C 1 178 ? 11.663  -1.319  13.653  1.00 26.33  ? 178 ASN C C   1 
ATOM   8581  O O   . ASN C 1 178 ? 11.443  -2.379  13.058  1.00 26.08  ? 178 ASN C O   1 
ATOM   8582  C CB  . ASN C 1 178 ? 10.187  -0.552  15.553  1.00 25.08  ? 178 ASN C CB  1 
ATOM   8583  C CG  . ASN C 1 178 ? 9.817   -0.805  17.009  1.00 27.63  ? 178 ASN C CG  1 
ATOM   8584  O OD1 . ASN C 1 178 ? 10.256  -1.781  17.620  1.00 27.69  ? 178 ASN C OD1 1 
ATOM   8585  N ND2 . ASN C 1 178 ? 8.989   0.056   17.554  1.00 26.95  ? 178 ASN C ND2 1 
ATOM   8586  N N   . MET C 1 179 ? 12.036  -0.201  13.044  1.00 24.08  ? 179 MET C N   1 
ATOM   8587  C CA  . MET C 1 179 ? 12.107  -0.148  11.593  1.00 24.62  ? 179 MET C CA  1 
ATOM   8588  C C   . MET C 1 179 ? 13.257  -1.025  11.106  1.00 26.34  ? 179 MET C C   1 
ATOM   8589  O O   . MET C 1 179 ? 13.069  -1.800  10.199  1.00 26.28  ? 179 MET C O   1 
ATOM   8590  C CB  . MET C 1 179 ? 12.272  1.277   11.087  1.00 25.75  ? 179 MET C CB  1 
ATOM   8591  C CG  . MET C 1 179 ? 12.257  1.319   9.566   1.00 27.59  ? 179 MET C CG  1 
ATOM   8592  S SD  . MET C 1 179 ? 12.692  2.873   8.865   1.00 29.76  ? 179 MET C SD  1 
ATOM   8593  C CE  . MET C 1 179 ? 14.466  2.701   9.064   1.00 30.81  ? 179 MET C CE  1 
ATOM   8594  N N   . LEU C 1 180 ? 14.431  -0.978  11.743  1.00 27.78  ? 180 LEU C N   1 
ATOM   8595  C CA  . LEU C 1 180 ? 15.536  -1.828  11.327  1.00 27.02  ? 180 LEU C CA  1 
ATOM   8596  C C   . LEU C 1 180 ? 15.152  -3.303  11.426  1.00 26.85  ? 180 LEU C C   1 
ATOM   8597  O O   . LEU C 1 180 ? 15.500  -4.089  10.545  1.00 27.36  ? 180 LEU C O   1 
ATOM   8598  C CB  . LEU C 1 180 ? 16.791  -1.538  12.157  1.00 26.94  ? 180 LEU C CB  1 
ATOM   8599  C CG  . LEU C 1 180 ? 17.461  -0.188  11.903  1.00 28.67  ? 180 LEU C CG  1 
ATOM   8600  C CD1 . LEU C 1 180 ? 18.514  0.075   12.962  1.00 28.49  ? 180 LEU C CD1 1 
ATOM   8601  C CD2 . LEU C 1 180 ? 18.106  -0.122  10.519  1.00 29.01  ? 180 LEU C CD2 1 
ATOM   8602  N N   . ALA C 1 181 ? 14.477  -3.700  12.509  1.00 25.12  ? 181 ALA C N   1 
ATOM   8603  C CA  . ALA C 1 181 ? 14.047  -5.073  12.673  1.00 26.53  ? 181 ALA C CA  1 
ATOM   8604  C C   . ALA C 1 181 ? 13.085  -5.486  11.562  1.00 26.57  ? 181 ALA C C   1 
ATOM   8605  O O   . ALA C 1 181 ? 13.143  -6.626  11.105  1.00 27.11  ? 181 ALA C O   1 
ATOM   8606  C CB  . ALA C 1 181 ? 13.435  -5.267  14.032  1.00 28.36  ? 181 ALA C CB  1 
ATOM   8607  N N   . ALA C 1 182 ? 12.245  -4.549  11.098  1.00 24.36  ? 182 ALA C N   1 
ATOM   8608  C CA  . ALA C 1 182 ? 11.263  -4.833  10.075  1.00 26.77  ? 182 ALA C CA  1 
ATOM   8609  C C   . ALA C 1 182 ? 11.911  -4.950  8.676   1.00 27.07  ? 182 ALA C C   1 
ATOM   8610  O O   . ALA C 1 182 ? 11.408  -5.662  7.833   1.00 25.61  ? 182 ALA C O   1 
ATOM   8611  C CB  . ALA C 1 182 ? 10.236  -3.728  10.102  1.00 28.24  ? 182 ALA C CB  1 
ATOM   8612  N N   . LEU C 1 183 ? 12.992  -4.216  8.397   1.00 24.43  ? 183 LEU C N   1 
ATOM   8613  C CA  . LEU C 1 183 ? 13.464  -4.086  7.027   1.00 26.72  ? 183 LEU C CA  1 
ATOM   8614  C C   . LEU C 1 183 ? 13.760  -5.447  6.403   1.00 23.12  ? 183 LEU C C   1 
ATOM   8615  O O   . LEU C 1 183 ? 13.304  -5.693  5.296   1.00 23.41  ? 183 LEU C O   1 
ATOM   8616  C CB  . LEU C 1 183 ? 14.668  -3.160  6.947   1.00 25.40  ? 183 LEU C CB  1 
ATOM   8617  C CG  . LEU C 1 183 ? 14.379  -1.701  7.247   1.00 24.63  ? 183 LEU C CG  1 
ATOM   8618  C CD1 . LEU C 1 183 ? 15.588  -0.870  6.932   1.00 27.62  ? 183 LEU C CD1 1 
ATOM   8619  C CD2 . LEU C 1 183 ? 13.175  -1.162  6.488   1.00 27.15  ? 183 LEU C CD2 1 
ATOM   8620  N N   . PRO C 1 184 ? 14.441  -6.411  7.047   1.00 26.63  ? 184 PRO C N   1 
ATOM   8621  C CA  . PRO C 1 184 ? 14.680  -7.691  6.398   1.00 24.96  ? 184 PRO C CA  1 
ATOM   8622  C C   . PRO C 1 184 ? 13.435  -8.549  6.191   1.00 28.46  ? 184 PRO C C   1 
ATOM   8623  O O   . PRO C 1 184 ? 13.374  -9.305  5.227   1.00 23.05  ? 184 PRO C O   1 
ATOM   8624  C CB  . PRO C 1 184 ? 15.709  -8.424  7.255   1.00 25.77  ? 184 PRO C CB  1 
ATOM   8625  C CG  . PRO C 1 184 ? 16.040  -7.497  8.375   1.00 30.72  ? 184 PRO C CG  1 
ATOM   8626  C CD  . PRO C 1 184 ? 15.109  -6.309  8.350   1.00 27.81  ? 184 PRO C CD  1 
ATOM   8627  N N   . VAL C 1 185 ? 12.437  -8.408  7.069   1.00 27.33  ? 185 VAL C N   1 
ATOM   8628  C CA  . VAL C 1 185 ? 11.169  -9.094  6.889   1.00 25.87  ? 185 VAL C CA  1 
ATOM   8629  C C   . VAL C 1 185 ? 10.457  -8.554  5.650   1.00 25.66  ? 185 VAL C C   1 
ATOM   8630  O O   . VAL C 1 185 ? 9.991   -9.332  4.817   1.00 24.98  ? 185 VAL C O   1 
ATOM   8631  C CB  . VAL C 1 185 ? 10.301  -9.000  8.156   1.00 26.12  ? 185 VAL C CB  1 
ATOM   8632  C CG1 . VAL C 1 185 ? 9.004   -9.755  7.985   1.00 27.52  ? 185 VAL C CG1 1 
ATOM   8633  C CG2 . VAL C 1 185 ? 11.038  -9.536  9.376   1.00 27.13  ? 185 VAL C CG2 1 
ATOM   8634  N N   . ILE C 1 186 ? 10.433  -7.233  5.491   1.00 24.85  ? 186 ILE C N   1 
ATOM   8635  C CA  . ILE C 1 186 ? 9.801   -6.602  4.336   1.00 25.95  ? 186 ILE C CA  1 
ATOM   8636  C C   . ILE C 1 186 ? 10.544  -6.948  3.038   1.00 26.72  ? 186 ILE C C   1 
ATOM   8637  O O   . ILE C 1 186 ? 9.919   -7.342  2.032   1.00 22.78  ? 186 ILE C O   1 
ATOM   8638  C CB  . ILE C 1 186 ? 9.697   -5.088  4.581   1.00 24.72  ? 186 ILE C CB  1 
ATOM   8639  C CG1 . ILE C 1 186 ? 8.692   -4.789  5.704   1.00 26.42  ? 186 ILE C CG1 1 
ATOM   8640  C CG2 . ILE C 1 186 ? 9.361   -4.321  3.314   1.00 24.62  ? 186 ILE C CG2 1 
ATOM   8641  C CD1 . ILE C 1 186 ? 8.689   -3.314  6.129   1.00 29.11  ? 186 ILE C CD1 1 
ATOM   8642  N N   . ALA C 1 187 ? 11.871  -6.799  3.070   1.00 25.68  ? 187 ALA C N   1 
ATOM   8643  C CA  . ALA C 1 187 ? 12.720  -7.126  1.935   1.00 24.00  ? 187 ALA C CA  1 
ATOM   8644  C C   . ALA C 1 187 ? 12.537  -8.586  1.503   1.00 24.53  ? 187 ALA C C   1 
ATOM   8645  O O   . ALA C 1 187 ? 12.403  -8.844  0.317   1.00 23.25  ? 187 ALA C O   1 
ATOM   8646  C CB  . ALA C 1 187 ? 14.155  -6.855  2.265   1.00 23.88  ? 187 ALA C CB  1 
ATOM   8647  N N   . ALA C 1 188 ? 12.606  -9.519  2.449   1.00 21.66  ? 188 ALA C N   1 
ATOM   8648  C CA  . ALA C 1 188 ? 12.456  -10.926 2.133   1.00 23.55  ? 188 ALA C CA  1 
ATOM   8649  C C   . ALA C 1 188 ? 11.059  -11.243 1.604   1.00 26.04  ? 188 ALA C C   1 
ATOM   8650  O O   . ALA C 1 188 ? 10.920  -12.122 0.765   1.00 23.82  ? 188 ALA C O   1 
ATOM   8651  C CB  . ALA C 1 188 ? 12.762  -11.758 3.329   1.00 24.61  ? 188 ALA C CB  1 
ATOM   8652  N N   . TYR C 1 189 ? 10.017  -10.575 2.124   1.00 26.35  ? 189 TYR C N   1 
ATOM   8653  C CA  . TYR C 1 189 ? 8.671   -10.780 1.615   1.00 23.64  ? 189 TYR C CA  1 
ATOM   8654  C C   . TYR C 1 189 ? 8.622   -10.482 0.128   1.00 25.52  ? 189 TYR C C   1 
ATOM   8655  O O   . TYR C 1 189 ? 8.048   -11.253 -0.653  1.00 23.81  ? 189 TYR C O   1 
ATOM   8656  C CB  . TYR C 1 189 ? 7.637   -9.904  2.312   1.00 23.63  ? 189 TYR C CB  1 
ATOM   8657  C CG  . TYR C 1 189 ? 6.227   -10.385 2.095   1.00 26.86  ? 189 TYR C CG  1 
ATOM   8658  C CD1 . TYR C 1 189 ? 5.727   -11.409 2.877   1.00 28.99  ? 189 TYR C CD1 1 
ATOM   8659  C CD2 . TYR C 1 189 ? 5.429   -9.892  1.085   1.00 30.58  ? 189 TYR C CD2 1 
ATOM   8660  C CE1 . TYR C 1 189 ? 4.445   -11.884 2.708   1.00 30.37  ? 189 TYR C CE1 1 
ATOM   8661  C CE2 . TYR C 1 189 ? 4.152   -10.392 0.875   1.00 29.90  ? 189 TYR C CE2 1 
ATOM   8662  C CZ  . TYR C 1 189 ? 3.663   -11.389 1.692   1.00 29.02  ? 189 TYR C CZ  1 
ATOM   8663  O OH  . TYR C 1 189 ? 2.413   -11.947 1.540   1.00 37.91  ? 189 TYR C OH  1 
ATOM   8664  N N   . ILE C 1 190 ? 9.139   -9.299  -0.234  1.00 21.70  ? 190 ILE C N   1 
ATOM   8665  C CA  . ILE C 1 190 ? 9.231   -8.846  -1.608  1.00 23.30  ? 190 ILE C CA  1 
ATOM   8666  C C   . ILE C 1 190 ? 9.988   -9.881  -2.466  1.00 26.71  ? 190 ILE C C   1 
ATOM   8667  O O   . ILE C 1 190 ? 9.518   -10.281 -3.536  1.00 27.10  ? 190 ILE C O   1 
ATOM   8668  C CB  . ILE C 1 190 ? 9.894   -7.448  -1.650  1.00 22.41  ? 190 ILE C CB  1 
ATOM   8669  C CG1 . ILE C 1 190 ? 8.964   -6.378  -1.066  1.00 24.49  ? 190 ILE C CG1 1 
ATOM   8670  C CG2 . ILE C 1 190 ? 10.298  -7.096  -3.072  1.00 21.52  ? 190 ILE C CG2 1 
ATOM   8671  C CD1 . ILE C 1 190 ? 9.677   -5.088  -0.680  1.00 25.28  ? 190 ILE C CD1 1 
ATOM   8672  N N   . TYR C 1 191 ? 11.169  -10.314 -1.996  1.00 24.56  ? 191 TYR C N   1 
ATOM   8673  C CA  . TYR C 1 191 ? 11.996  -11.276 -2.712  1.00 23.57  ? 191 TYR C CA  1 
ATOM   8674  C C   . TYR C 1 191 ? 11.236  -12.582 -2.967  1.00 22.44  ? 191 TYR C C   1 
ATOM   8675  O O   . TYR C 1 191 ? 11.191  -13.094 -4.063  1.00 23.65  ? 191 TYR C O   1 
ATOM   8676  C CB  . TYR C 1 191 ? 13.258  -11.538 -1.896  1.00 22.92  ? 191 TYR C CB  1 
ATOM   8677  C CG  . TYR C 1 191 ? 14.262  -12.376 -2.624  1.00 22.86  ? 191 TYR C CG  1 
ATOM   8678  C CD1 . TYR C 1 191 ? 14.995  -11.839 -3.660  1.00 24.01  ? 191 TYR C CD1 1 
ATOM   8679  C CD2 . TYR C 1 191 ? 14.435  -13.716 -2.318  1.00 22.47  ? 191 TYR C CD2 1 
ATOM   8680  C CE1 . TYR C 1 191 ? 15.905  -12.595 -4.367  1.00 24.27  ? 191 TYR C CE1 1 
ATOM   8681  C CE2 . TYR C 1 191 ? 15.349  -14.483 -3.007  1.00 26.15  ? 191 TYR C CE2 1 
ATOM   8682  C CZ  . TYR C 1 191 ? 16.089  -13.918 -4.031  1.00 25.09  ? 191 TYR C CZ  1 
ATOM   8683  O OH  . TYR C 1 191 ? 17.021  -14.657 -4.709  1.00 26.96  ? 191 TYR C OH  1 
ATOM   8684  N N   . ARG C 1 192 ? 10.603  -13.129 -1.941  1.00 22.06  ? 192 ARG C N   1 
ATOM   8685  C CA  . ARG C 1 192 ? 9.915   -14.399 -2.045  1.00 24.78  ? 192 ARG C CA  1 
ATOM   8686  C C   . ARG C 1 192 ? 8.684   -14.280 -2.948  1.00 26.60  ? 192 ARG C C   1 
ATOM   8687  O O   . ARG C 1 192 ? 8.408   -15.169 -3.768  1.00 25.21  ? 192 ARG C O   1 
ATOM   8688  C CB  . ARG C 1 192 ? 9.512   -14.886 -0.645  1.00 25.29  ? 192 ARG C CB  1 
ATOM   8689  C CG  . ARG C 1 192 ? 10.658  -15.192 0.310   1.00 25.46  ? 192 ARG C CG  1 
ATOM   8690  C CD  . ARG C 1 192 ? 11.580  -16.317 -0.148  1.00 27.78  ? 192 ARG C CD  1 
ATOM   8691  N NE  . ARG C 1 192 ? 10.934  -17.604 -0.317  1.00 28.71  ? 192 ARG C NE  1 
ATOM   8692  C CZ  . ARG C 1 192 ? 11.569  -18.700 -0.737  1.00 34.10  ? 192 ARG C CZ  1 
ATOM   8693  N NH1 . ARG C 1 192 ? 12.867  -18.688 -0.934  1.00 28.51  ? 192 ARG C NH1 1 
ATOM   8694  N NH2 . ARG C 1 192 ? 10.915  -19.825 -0.934  1.00 33.39  ? 192 ARG C NH2 1 
ATOM   8695  N N   . ARG C 1 193 ? 7.939   -13.186 -2.792  1.00 23.93  ? 193 ARG C N   1 
ATOM   8696  C CA  . ARG C 1 193 ? 6.739   -12.990 -3.581  1.00 22.79  ? 193 ARG C CA  1 
ATOM   8697  C C   . ARG C 1 193 ? 7.055   -12.833 -5.064  1.00 25.29  ? 193 ARG C C   1 
ATOM   8698  O O   . ARG C 1 193 ? 6.375   -13.438 -5.892  1.00 27.54  ? 193 ARG C O   1 
ATOM   8699  C CB  . ARG C 1 193 ? 5.920   -11.795 -3.122  1.00 23.22  ? 193 ARG C CB  1 
ATOM   8700  C CG  . ARG C 1 193 ? 4.601   -11.697 -3.879  1.00 25.44  ? 193 ARG C CG  1 
ATOM   8701  C CD  . ARG C 1 193 ? 3.705   -10.602 -3.372  1.00 27.27  ? 193 ARG C CD  1 
ATOM   8702  N NE  . ARG C 1 193 ? 2.501   -10.524 -4.169  1.00 24.64  ? 193 ARG C NE  1 
ATOM   8703  C CZ  . ARG C 1 193 ? 2.009   -9.414  -4.696  1.00 25.68  ? 193 ARG C CZ  1 
ATOM   8704  N NH1 . ARG C 1 193 ? 2.594   -8.262  -4.485  1.00 26.72  ? 193 ARG C NH1 1 
ATOM   8705  N NH2 . ARG C 1 193 ? 0.893   -9.458  -5.404  1.00 28.45  ? 193 ARG C NH2 1 
ATOM   8706  N N   . LYS C 1 194 ? 8.046   -12.009 -5.408  1.00 21.35  ? 194 LYS C N   1 
ATOM   8707  C CA  . LYS C 1 194 ? 8.364   -11.720 -6.797  1.00 25.40  ? 194 LYS C CA  1 
ATOM   8708  C C   . LYS C 1 194 ? 9.104   -12.874 -7.474  1.00 26.03  ? 194 LYS C C   1 
ATOM   8709  O O   . LYS C 1 194 ? 8.810   -13.195 -8.611  1.00 25.00  ? 194 LYS C O   1 
ATOM   8710  C CB  . LYS C 1 194 ? 9.235   -10.465 -6.904  1.00 27.08  ? 194 LYS C CB  1 
ATOM   8711  C CG  . LYS C 1 194 ? 8.496   -9.160  -6.672  1.00 26.86  ? 194 LYS C CG  1 
ATOM   8712  C CD  . LYS C 1 194 ? 9.325   -7.945  -6.960  1.00 28.36  ? 194 LYS C CD  1 
ATOM   8713  C CE  . LYS C 1 194 ? 9.683   -7.839  -8.427  1.00 30.58  ? 194 LYS C CE  1 
ATOM   8714  N NZ  . LYS C 1 194 ? 8.583   -7.226  -9.192  1.00 28.18  ? 194 LYS C NZ  1 
ATOM   8715  N N   . TYR C 1 195 ? 10.049  -13.510 -6.787  1.00 27.65  ? 195 TYR C N   1 
ATOM   8716  C CA  . TYR C 1 195 ? 11.058  -14.300 -7.471  1.00 26.36  ? 195 TYR C CA  1 
ATOM   8717  C C   . TYR C 1 195 ? 11.098  -15.757 -7.027  1.00 28.10  ? 195 TYR C C   1 
ATOM   8718  O O   . TYR C 1 195 ? 11.735  -16.538 -7.700  1.00 29.08  ? 195 TYR C O   1 
ATOM   8719  C CB  . TYR C 1 195 ? 12.437  -13.710 -7.190  1.00 25.71  ? 195 TYR C CB  1 
ATOM   8720  C CG  . TYR C 1 195 ? 12.555  -12.252 -7.558  1.00 25.20  ? 195 TYR C CG  1 
ATOM   8721  C CD1 . TYR C 1 195 ? 12.376  -11.797 -8.865  1.00 25.15  ? 195 TYR C CD1 1 
ATOM   8722  C CD2 . TYR C 1 195 ? 12.868  -11.326 -6.595  1.00 27.53  ? 195 TYR C CD2 1 
ATOM   8723  C CE1 . TYR C 1 195 ? 12.501  -10.455 -9.195  1.00 25.57  ? 195 TYR C CE1 1 
ATOM   8724  C CE2 . TYR C 1 195 ? 12.996  -9.984  -6.906  1.00 25.81  ? 195 TYR C CE2 1 
ATOM   8725  C CZ  . TYR C 1 195 ? 12.806  -9.545  -8.197  1.00 25.74  ? 195 TYR C CZ  1 
ATOM   8726  O OH  . TYR C 1 195 ? 12.987  -8.208  -8.349  1.00 26.11  ? 195 TYR C OH  1 
ATOM   8727  N N   . LYS C 1 196 ? 10.477  -16.146 -5.907  1.00 26.60  ? 196 LYS C N   1 
ATOM   8728  C CA  . LYS C 1 196 ? 10.640  -17.505 -5.436  1.00 27.56  ? 196 LYS C CA  1 
ATOM   8729  C C   . LYS C 1 196 ? 9.285   -18.187 -5.189  1.00 29.82  ? 196 LYS C C   1 
ATOM   8730  O O   . LYS C 1 196 ? 9.151   -18.918 -4.244  1.00 32.00  ? 196 LYS C O   1 
ATOM   8731  C CB  . LYS C 1 196 ? 11.464  -17.507 -4.145  1.00 27.84  ? 196 LYS C CB  1 
ATOM   8732  C CG  . LYS C 1 196 ? 12.877  -16.954 -4.279  1.00 29.79  ? 196 LYS C CG  1 
ATOM   8733  C CD  . LYS C 1 196 ? 13.783  -17.931 -5.023  1.00 32.80  ? 196 LYS C CD  1 
ATOM   8734  C CE  . LYS C 1 196 ? 15.099  -17.307 -5.395  1.00 37.06  ? 196 LYS C CE  1 
ATOM   8735  N NZ  . LYS C 1 196 ? 15.986  -18.285 -6.039  1.00 43.85  ? 196 LYS C NZ  1 
ATOM   8736  N N   . GLY C 1 197 ? 8.276   -17.936 -6.010  1.00 29.25  ? 197 GLY C N   1 
ATOM   8737  C CA  . GLY C 1 197 ? 7.022   -18.668 -5.958  1.00 32.85  ? 197 GLY C CA  1 
ATOM   8738  C C   . GLY C 1 197 ? 6.104   -18.330 -4.777  1.00 28.12  ? 197 GLY C C   1 
ATOM   8739  O O   . GLY C 1 197 ? 5.160   -19.072 -4.509  1.00 27.21  ? 197 GLY C O   1 
ATOM   8740  N N   . ASP C 1 198 ? 6.335   -17.198 -4.097  1.00 25.09  ? 198 ASP C N   1 
ATOM   8741  C CA  . ASP C 1 198 ? 5.380   -16.650 -3.133  1.00 24.25  ? 198 ASP C CA  1 
ATOM   8742  C C   . ASP C 1 198 ? 5.172   -17.624 -1.992  1.00 23.56  ? 198 ASP C C   1 
ATOM   8743  O O   . ASP C 1 198 ? 4.066   -17.782 -1.489  1.00 23.10  ? 198 ASP C O   1 
ATOM   8744  C CB  . ASP C 1 198 ? 4.033   -16.337 -3.770  1.00 24.04  ? 198 ASP C CB  1 
ATOM   8745  C CG  . ASP C 1 198 ? 3.100   -15.410 -2.997  1.00 27.93  ? 198 ASP C CG  1 
ATOM   8746  O OD1 . ASP C 1 198 ? 3.542   -14.722 -2.013  1.00 26.30  ? 198 ASP C OD1 1 
ATOM   8747  O OD2 . ASP C 1 198 ? 1.919   -15.392 -3.384  1.00 27.75  ? 198 ASP C OD2 1 
ATOM   8748  N N   . THR C 1 199 ? 6.261   -18.263 -1.577  1.00 26.33  ? 199 THR C N   1 
ATOM   8749  C CA  . THR C 1 199 ? 6.298   -19.033 -0.347  1.00 27.37  ? 199 THR C CA  1 
ATOM   8750  C C   . THR C 1 199 ? 7.216   -18.303 0.635   1.00 28.60  ? 199 THR C C   1 
ATOM   8751  O O   . THR C 1 199 ? 8.241   -17.770 0.226   1.00 26.07  ? 199 THR C O   1 
ATOM   8752  C CB  . THR C 1 199 ? 6.839   -20.438 -0.638  1.00 32.95  ? 199 THR C CB  1 
ATOM   8753  O OG1 . THR C 1 199 ? 8.129   -20.242 -1.199  1.00 35.37  ? 199 THR C OG1 1 
ATOM   8754  C CG2 . THR C 1 199 ? 6.027   -21.216 -1.655  1.00 35.21  ? 199 THR C CG2 1 
ATOM   8755  N N   . HIS C 1 200 ? 6.875   -18.293 1.919   1.00 25.79  ? 200 HIS C N   1 
ATOM   8756  C CA  . HIS C 1 200 ? 7.434   -17.334 2.854   1.00 30.10  ? 200 HIS C CA  1 
ATOM   8757  C C   . HIS C 1 200 ? 8.116   -18.078 3.998   1.00 35.78  ? 200 HIS C C   1 
ATOM   8758  O O   . HIS C 1 200 ? 7.591   -19.079 4.445   1.00 37.26  ? 200 HIS C O   1 
ATOM   8759  C CB  . HIS C 1 200 ? 6.346   -16.363 3.325   1.00 28.65  ? 200 HIS C CB  1 
ATOM   8760  C CG  . HIS C 1 200 ? 5.896   -15.563 2.168   1.00 28.59  ? 200 HIS C CG  1 
ATOM   8761  N ND1 . HIS C 1 200 ? 6.637   -14.509 1.678   1.00 26.87  ? 200 HIS C ND1 1 
ATOM   8762  C CD2 . HIS C 1 200 ? 4.915   -15.773 1.282   1.00 29.54  ? 200 HIS C CD2 1 
ATOM   8763  C CE1 . HIS C 1 200 ? 6.076   -14.052 0.566   1.00 28.36  ? 200 HIS C CE1 1 
ATOM   8764  N NE2 . HIS C 1 200 ? 5.026   -14.816 0.293   1.00 27.21  ? 200 HIS C NE2 1 
ATOM   8765  N N   . ILE C 1 201 ? 9.278   -17.575 4.458   1.00 32.88  ? 201 ILE C N   1 
ATOM   8766  C CA  . ILE C 1 201 ? 10.078  -18.222 5.494   1.00 32.69  ? 201 ILE C CA  1 
ATOM   8767  C C   . ILE C 1 201 ? 10.130  -17.273 6.685   1.00 33.34  ? 201 ILE C C   1 
ATOM   8768  O O   . ILE C 1 201 ? 10.454  -16.101 6.525   1.00 30.08  ? 201 ILE C O   1 
ATOM   8769  C CB  . ILE C 1 201 ? 11.477  -18.598 4.960   1.00 36.50  ? 201 ILE C CB  1 
ATOM   8770  C CG1 . ILE C 1 201 ? 11.368  -19.564 3.778   1.00 37.04  ? 201 ILE C CG1 1 
ATOM   8771  C CG2 . ILE C 1 201 ? 12.388  -19.185 6.040   1.00 37.46  ? 201 ILE C CG2 1 
ATOM   8772  C CD1 . ILE C 1 201 ? 12.585  -19.556 2.892   1.00 36.09  ? 201 ILE C CD1 1 
ATOM   8773  N N   . ALA C 1 202 ? 9.800   -17.802 7.873   1.00 33.24  ? 202 ALA C N   1 
ATOM   8774  C CA  . ALA C 1 202 ? 9.791   -17.040 9.112   1.00 35.47  ? 202 ALA C CA  1 
ATOM   8775  C C   . ALA C 1 202 ? 11.217  -16.699 9.540   1.00 29.91  ? 202 ALA C C   1 
ATOM   8776  O O   . ALA C 1 202 ? 12.171  -17.424 9.236   1.00 33.28  ? 202 ALA C O   1 
ATOM   8777  C CB  . ALA C 1 202 ? 9.085   -17.865 10.193  1.00 37.63  ? 202 ALA C CB  1 
ATOM   8778  N N   . PRO C 1 203 ? 11.408  -15.617 10.316  1.00 32.76  ? 203 PRO C N   1 
ATOM   8779  C CA  . PRO C 1 203 ? 12.708  -15.334 10.894  1.00 34.22  ? 203 PRO C CA  1 
ATOM   8780  C C   . PRO C 1 203 ? 13.131  -16.475 11.803  1.00 37.09  ? 203 PRO C C   1 
ATOM   8781  O O   . PRO C 1 203 ? 12.286  -17.155 12.375  1.00 37.96  ? 203 PRO C O   1 
ATOM   8782  C CB  . PRO C 1 203 ? 12.542  -14.063 11.721  1.00 36.54  ? 203 PRO C CB  1 
ATOM   8783  C CG  . PRO C 1 203 ? 11.112  -13.614 11.543  1.00 34.69  ? 203 PRO C CG  1 
ATOM   8784  C CD  . PRO C 1 203 ? 10.375  -14.644 10.722  1.00 34.47  ? 203 PRO C CD  1 
ATOM   8785  N N   . ASP C 1 204 ? 14.439  -16.660 11.887  1.00 35.79  ? 204 ASP C N   1 
ATOM   8786  C CA  . ASP C 1 204 ? 15.048  -17.609 12.796  1.00 41.33  ? 204 ASP C CA  1 
ATOM   8787  C C   . ASP C 1 204 ? 15.478  -16.846 14.051  1.00 42.51  ? 204 ASP C C   1 
ATOM   8788  O O   . ASP C 1 204 ? 16.341  -15.976 13.990  1.00 38.48  ? 204 ASP C O   1 
ATOM   8789  C CB  . ASP C 1 204 ? 16.191  -18.348 12.093  1.00 41.80  ? 204 ASP C CB  1 
ATOM   8790  C CG  . ASP C 1 204 ? 16.905  -19.360 12.981  1.00 43.20  ? 204 ASP C CG  1 
ATOM   8791  O OD1 . ASP C 1 204 ? 16.866  -19.198 14.215  1.00 44.94  ? 204 ASP C OD1 1 
ATOM   8792  O OD2 . ASP C 1 204 ? 17.488  -20.289 12.432  1.00 53.37  ? 204 ASP C OD2 1 
ATOM   8793  N N   . PRO C 1 205 ? 14.881  -17.118 15.231  1.00 44.91  ? 205 PRO C N   1 
ATOM   8794  C CA  . PRO C 1 205 ? 15.246  -16.383 16.444  1.00 45.54  ? 205 PRO C CA  1 
ATOM   8795  C C   . PRO C 1 205 ? 16.716  -16.522 16.852  1.00 39.22  ? 205 PRO C C   1 
ATOM   8796  O O   . PRO C 1 205 ? 17.192  -15.710 17.621  1.00 45.63  ? 205 PRO C O   1 
ATOM   8797  C CB  . PRO C 1 205 ? 14.334  -17.000 17.519  1.00 49.33  ? 205 PRO C CB  1 
ATOM   8798  C CG  . PRO C 1 205 ? 14.017  -18.388 16.965  1.00 51.71  ? 205 PRO C CG  1 
ATOM   8799  C CD  . PRO C 1 205 ? 13.879  -18.174 15.474  1.00 46.07  ? 205 PRO C CD  1 
ATOM   8800  N N   . ASN C 1 206 ? 17.463  -17.476 16.287  1.00 36.95  ? 206 ASN C N   1 
ATOM   8801  C CA  . ASN C 1 206 ? 18.861  -17.668 16.676  1.00 43.98  ? 206 ASN C CA  1 
ATOM   8802  C C   . ASN C 1 206 ? 19.873  -17.065 15.697  1.00 42.71  ? 206 ASN C C   1 
ATOM   8803  O O   . ASN C 1 206 ? 21.070  -17.245 15.892  1.00 45.62  ? 206 ASN C O   1 
ATOM   8804  C CB  . ASN C 1 206 ? 19.217  -19.149 16.822  1.00 48.14  ? 206 ASN C CB  1 
ATOM   8805  C CG  . ASN C 1 206 ? 18.428  -19.815 17.928  1.00 54.49  ? 206 ASN C CG  1 
ATOM   8806  O OD1 . ASN C 1 206 ? 18.259  -19.252 19.011  1.00 62.20  ? 206 ASN C OD1 1 
ATOM   8807  N ND2 . ASN C 1 206 ? 17.904  -20.990 17.641  1.00 57.31  ? 206 ASN C ND2 1 
ATOM   8808  N N   . LEU C 1 207 ? 19.430  -16.355 14.651  1.00 39.96  ? 207 LEU C N   1 
ATOM   8809  C CA  . LEU C 1 207 ? 20.376  -15.754 13.721  1.00 36.46  ? 207 LEU C CA  1 
ATOM   8810  C C   . LEU C 1 207 ? 20.490  -14.262 14.013  1.00 34.00  ? 207 LEU C C   1 
ATOM   8811  O O   . LEU C 1 207 ? 19.557  -13.650 14.512  1.00 36.67  ? 207 LEU C O   1 
ATOM   8812  C CB  . LEU C 1 207 ? 19.943  -16.028 12.274  1.00 33.77  ? 207 LEU C CB  1 
ATOM   8813  C CG  . LEU C 1 207 ? 20.102  -17.462 11.760  1.00 36.35  ? 207 LEU C CG  1 
ATOM   8814  C CD1 . LEU C 1 207 ? 19.578  -17.564 10.338  1.00 37.30  ? 207 LEU C CD1 1 
ATOM   8815  C CD2 . LEU C 1 207 ? 21.547  -17.952 11.768  1.00 36.38  ? 207 LEU C CD2 1 
ATOM   8816  N N   . ASP C 1 208 ? 21.651  -13.682 13.688  1.00 31.15  ? 208 ASP C N   1 
ATOM   8817  C CA  . ASP C 1 208 ? 21.822  -12.237 13.682  1.00 30.85  ? 208 ASP C CA  1 
ATOM   8818  C C   . ASP C 1 208 ? 21.022  -11.596 12.526  1.00 30.31  ? 208 ASP C C   1 
ATOM   8819  O O   . ASP C 1 208 ? 20.468  -12.285 11.692  1.00 30.62  ? 208 ASP C O   1 
ATOM   8820  C CB  . ASP C 1 208 ? 23.324  -11.940 13.568  1.00 32.28  ? 208 ASP C CB  1 
ATOM   8821  C CG  . ASP C 1 208 ? 24.005  -12.654 12.409  1.00 33.83  ? 208 ASP C CG  1 
ATOM   8822  O OD1 . ASP C 1 208 ? 24.182  -13.871 12.503  1.00 36.17  ? 208 ASP C OD1 1 
ATOM   8823  O OD2 . ASP C 1 208 ? 24.295  -11.995 11.377  1.00 34.54  ? 208 ASP C OD2 1 
ATOM   8824  N N   . TRP C 1 209 ? 21.036  -10.262 12.436  1.00 29.61  ? 209 TRP C N   1 
ATOM   8825  C CA  . TRP C 1 209 ? 20.160  -9.492  11.576  1.00 31.11  ? 209 TRP C CA  1 
ATOM   8826  C C   . TRP C 1 209 ? 20.411  -9.783  10.088  1.00 29.51  ? 209 TRP C C   1 
ATOM   8827  O O   . TRP C 1 209 ? 19.454  -10.026 9.348   1.00 27.83  ? 209 TRP C O   1 
ATOM   8828  C CB  . TRP C 1 209 ? 20.387  -8.023  11.939  1.00 33.56  ? 209 TRP C CB  1 
ATOM   8829  C CG  . TRP C 1 209 ? 19.554  -6.989  11.231  1.00 29.35  ? 209 TRP C CG  1 
ATOM   8830  C CD1 . TRP C 1 209 ? 18.246  -6.670  11.441  1.00 29.08  ? 209 TRP C CD1 1 
ATOM   8831  C CD2 . TRP C 1 209 ? 20.019  -6.075  10.240  1.00 27.90  ? 209 TRP C CD2 1 
ATOM   8832  N NE1 . TRP C 1 209 ? 17.886  -5.575  10.701  1.00 29.46  ? 209 TRP C NE1 1 
ATOM   8833  C CE2 . TRP C 1 209 ? 18.956  -5.188  9.955   1.00 29.59  ? 209 TRP C CE2 1 
ATOM   8834  C CE3 . TRP C 1 209 ? 21.261  -5.863  9.634   1.00 31.47  ? 209 TRP C CE3 1 
ATOM   8835  C CZ2 . TRP C 1 209 ? 19.079  -4.156  9.032   1.00 30.15  ? 209 TRP C CZ2 1 
ATOM   8836  C CZ3 . TRP C 1 209 ? 21.375  -4.857  8.710   1.00 31.37  ? 209 TRP C CZ3 1 
ATOM   8837  C CH2 . TRP C 1 209 ? 20.296  -4.026  8.408   1.00 31.07  ? 209 TRP C CH2 1 
ATOM   8838  N N   . SER C 1 210 ? 21.691  -9.809  9.672   1.00 27.10  ? 210 SER C N   1 
ATOM   8839  C CA  . SER C 1 210 ? 22.109  -10.033 8.291   1.00 29.04  ? 210 SER C CA  1 
ATOM   8840  C C   . SER C 1 210 ? 21.810  -11.448 7.843   1.00 31.43  ? 210 SER C C   1 
ATOM   8841  O O   . SER C 1 210 ? 21.341  -11.660 6.727   1.00 29.14  ? 210 SER C O   1 
ATOM   8842  C CB  . SER C 1 210 ? 23.594  -9.794  8.066   1.00 30.39  ? 210 SER C CB  1 
ATOM   8843  O OG  . SER C 1 210 ? 23.957  -8.495  8.470   1.00 33.43  ? 210 SER C OG  1 
ATOM   8844  N N   . ALA C 1 211 ? 22.137  -12.414 8.701   1.00 31.58  ? 211 ALA C N   1 
ATOM   8845  C CA  . ALA C 1 211 ? 21.939  -13.815 8.382   1.00 31.85  ? 211 ALA C CA  1 
ATOM   8846  C C   . ALA C 1 211 ? 20.445  -14.117 8.288   1.00 31.27  ? 211 ALA C C   1 
ATOM   8847  O O   . ALA C 1 211 ? 20.039  -14.988 7.516   1.00 29.44  ? 211 ALA C O   1 
ATOM   8848  C CB  . ALA C 1 211 ? 22.610  -14.683 9.433   1.00 31.66  ? 211 ALA C CB  1 
ATOM   8849  N N   . ASN C 1 212 ? 19.658  -13.432 9.116   1.00 27.78  ? 212 ASN C N   1 
ATOM   8850  C CA  . ASN C 1 212 ? 18.219  -13.579 9.051   1.00 30.04  ? 212 ASN C CA  1 
ATOM   8851  C C   . ASN C 1 212 ? 17.642  -13.161 7.700   1.00 26.74  ? 212 ASN C C   1 
ATOM   8852  O O   . ASN C 1 212 ? 16.713  -13.809 7.221   1.00 25.24  ? 212 ASN C O   1 
ATOM   8853  C CB  . ASN C 1 212 ? 17.440  -12.845 10.132  1.00 32.34  ? 212 ASN C CB  1 
ATOM   8854  C CG  . ASN C 1 212 ? 16.763  -13.843 11.055  1.00 38.82  ? 212 ASN C CG  1 
ATOM   8855  O OD1 . ASN C 1 212 ? 16.318  -14.914 10.620  1.00 35.15  ? 212 ASN C OD1 1 
ATOM   8856  N ND2 . ASN C 1 212 ? 16.790  -13.561 12.348  1.00 35.70  ? 212 ASN C ND2 1 
ATOM   8857  N N   . LEU C 1 213 ? 18.162  -12.102 7.097   1.00 25.57  ? 213 LEU C N   1 
ATOM   8858  C CA  . LEU C 1 213 ? 17.689  -11.708 5.777   1.00 30.88  ? 213 LEU C CA  1 
ATOM   8859  C C   . LEU C 1 213 ? 17.970  -12.809 4.758   1.00 26.36  ? 213 LEU C C   1 
ATOM   8860  O O   . LEU C 1 213 ? 17.104  -13.151 3.951   1.00 28.12  ? 213 LEU C O   1 
ATOM   8861  C CB  . LEU C 1 213 ? 18.344  -10.395 5.363   1.00 26.40  ? 213 LEU C CB  1 
ATOM   8862  C CG  . LEU C 1 213 ? 18.070  -9.949  3.927   1.00 28.53  ? 213 LEU C CG  1 
ATOM   8863  C CD1 . LEU C 1 213 ? 16.599  -9.877  3.615   1.00 28.12  ? 213 LEU C CD1 1 
ATOM   8864  C CD2 . LEU C 1 213 ? 18.697  -8.588  3.719   1.00 32.75  ? 213 LEU C CD2 1 
ATOM   8865  N N   . ALA C 1 214 ? 19.185  -13.351 4.787   1.00 27.38  ? 214 ALA C N   1 
ATOM   8866  C CA  . ALA C 1 214 ? 19.564  -14.429 3.889   1.00 26.45  ? 214 ALA C CA  1 
ATOM   8867  C C   . ALA C 1 214 ? 18.651  -15.640 4.075   1.00 26.73  ? 214 ALA C C   1 
ATOM   8868  O O   . ALA C 1 214 ? 18.150  -16.200 3.105   1.00 24.71  ? 214 ALA C O   1 
ATOM   8869  C CB  . ALA C 1 214 ? 21.016  -14.804 4.095   1.00 29.05  ? 214 ALA C CB  1 
ATOM   8870  N N   . HIS C 1 215 ? 18.493  -16.061 5.337   1.00 23.99  ? 215 HIS C N   1 
ATOM   8871  C CA  . HIS C 1 215 ? 17.650  -17.167 5.714   1.00 27.18  ? 215 HIS C CA  1 
ATOM   8872  C C   . HIS C 1 215 ? 16.248  -16.966 5.148   1.00 29.45  ? 215 HIS C C   1 
ATOM   8873  O O   . HIS C 1 215 ? 15.697  -17.863 4.532   1.00 30.15  ? 215 HIS C O   1 
ATOM   8874  C CB  . HIS C 1 215 ? 17.576  -17.255 7.243   1.00 27.55  ? 215 HIS C CB  1 
ATOM   8875  C CG  . HIS C 1 215 ? 16.608  -18.280 7.715   1.00 28.76  ? 215 HIS C CG  1 
ATOM   8876  N ND1 . HIS C 1 215 ? 16.758  -19.629 7.483   1.00 32.03  ? 215 HIS C ND1 1 
ATOM   8877  C CD2 . HIS C 1 215 ? 15.494  -18.151 8.448   1.00 29.32  ? 215 HIS C CD2 1 
ATOM   8878  C CE1 . HIS C 1 215 ? 15.746  -20.281 8.028   1.00 31.11  ? 215 HIS C CE1 1 
ATOM   8879  N NE2 . HIS C 1 215 ? 14.991  -19.408 8.655   1.00 32.48  ? 215 HIS C NE2 1 
ATOM   8880  N N   . MET C 1 216 ? 15.687  -15.763 5.343   1.00 28.32  ? 216 MET C N   1 
ATOM   8881  C CA  . MET C 1 216 ? 14.316  -15.507 4.951   1.00 27.65  ? 216 MET C CA  1 
ATOM   8882  C C   . MET C 1 216 ? 14.193  -15.393 3.425   1.00 30.00  ? 216 MET C C   1 
ATOM   8883  O O   . MET C 1 216 ? 13.101  -15.577 2.881   1.00 25.33  ? 216 MET C O   1 
ATOM   8884  C CB  . MET C 1 216 ? 13.828  -14.241 5.648   1.00 28.25  ? 216 MET C CB  1 
ATOM   8885  C CG  . MET C 1 216 ? 13.492  -14.473 7.116   1.00 26.66  ? 216 MET C CG  1 
ATOM   8886  S SD  . MET C 1 216 ? 12.636  -13.050 7.864   1.00 28.85  ? 216 MET C SD  1 
ATOM   8887  C CE  . MET C 1 216 ? 13.860  -11.759 7.644   1.00 27.85  ? 216 MET C CE  1 
ATOM   8888  N N   . MET C 1 217 ? 15.320  -15.141 2.727   1.00 27.34  ? 217 MET C N   1 
ATOM   8889  C CA  . MET C 1 217 ? 15.329  -15.149 1.272   1.00 26.38  ? 217 MET C CA  1 
ATOM   8890  C C   . MET C 1 217 ? 15.460  -16.570 0.717   1.00 27.34  ? 217 MET C C   1 
ATOM   8891  O O   . MET C 1 217 ? 15.147  -16.800 -0.459  1.00 28.25  ? 217 MET C O   1 
ATOM   8892  C CB  . MET C 1 217 ? 16.464  -14.272 0.723   1.00 27.33  ? 217 MET C CB  1 
ATOM   8893  C CG  . MET C 1 217 ? 16.165  -12.784 0.865   1.00 25.06  ? 217 MET C CG  1 
ATOM   8894  S SD  . MET C 1 217 ? 17.608  -11.768 0.502   1.00 27.36  ? 217 MET C SD  1 
ATOM   8895  C CE  . MET C 1 217 ? 17.954  -12.270 -1.184  1.00 29.01  ? 217 MET C CE  1 
ATOM   8896  N N   . GLY C 1 218 ? 15.898  -17.523 1.549   1.00 27.01  ? 218 GLY C N   1 
ATOM   8897  C CA  . GLY C 1 218 ? 16.045  -18.906 1.126   1.00 26.96  ? 218 GLY C CA  1 
ATOM   8898  C C   . GLY C 1 218 ? 17.487  -19.413 1.055   1.00 32.36  ? 218 GLY C C   1 
ATOM   8899  O O   . GLY C 1 218 ? 17.692  -20.476 0.499   1.00 31.40  ? 218 GLY C O   1 
ATOM   8900  N N   . PHE C 1 219 ? 18.462  -18.694 1.649   1.00 29.73  ? 219 PHE C N   1 
ATOM   8901  C CA  . PHE C 1 219 ? 19.875  -19.039 1.557   1.00 31.53  ? 219 PHE C CA  1 
ATOM   8902  C C   . PHE C 1 219 ? 20.420  -19.288 2.960   1.00 35.14  ? 219 PHE C C   1 
ATOM   8903  O O   . PHE C 1 219 ? 20.370  -18.376 3.774   1.00 37.76  ? 219 PHE C O   1 
ATOM   8904  C CB  . PHE C 1 219 ? 20.683  -17.883 0.953   1.00 31.05  ? 219 PHE C CB  1 
ATOM   8905  C CG  . PHE C 1 219 ? 20.267  -17.563 -0.456  1.00 34.75  ? 219 PHE C CG  1 
ATOM   8906  C CD1 . PHE C 1 219 ? 19.219  -16.679 -0.698  1.00 36.70  ? 219 PHE C CD1 1 
ATOM   8907  C CD2 . PHE C 1 219 ? 20.801  -18.260 -1.522  1.00 34.06  ? 219 PHE C CD2 1 
ATOM   8908  C CE1 . PHE C 1 219 ? 18.774  -16.445 -1.987  1.00 38.20  ? 219 PHE C CE1 1 
ATOM   8909  C CE2 . PHE C 1 219 ? 20.349  -18.041 -2.814  1.00 38.88  ? 219 PHE C CE2 1 
ATOM   8910  C CZ  . PHE C 1 219 ? 19.345  -17.120 -3.053  1.00 39.08  ? 219 PHE C CZ  1 
ATOM   8911  N N   . ASP C 1 220 ? 20.973  -20.479 3.227   1.00 35.53  ? 220 ASP C N   1 
ATOM   8912  C CA  . ASP C 1 220 ? 21.414  -20.807 4.579   1.00 35.03  ? 220 ASP C CA  1 
ATOM   8913  C C   . ASP C 1 220 ? 22.882  -21.222 4.657   1.00 34.67  ? 220 ASP C C   1 
ATOM   8914  O O   . ASP C 1 220 ? 23.360  -21.509 5.752   1.00 35.89  ? 220 ASP C O   1 
ATOM   8915  C CB  . ASP C 1 220 ? 20.484  -21.853 5.196   1.00 37.83  ? 220 ASP C CB  1 
ATOM   8916  C CG  . ASP C 1 220 ? 19.128  -21.243 5.522   1.00 43.91  ? 220 ASP C CG  1 
ATOM   8917  O OD1 . ASP C 1 220 ? 19.068  -20.323 6.391   1.00 43.41  ? 220 ASP C OD1 1 
ATOM   8918  O OD2 . ASP C 1 220 ? 18.144  -21.658 4.887   1.00 42.75  ? 220 ASP C OD2 1 
ATOM   8919  N N   . ASP C 1 221 ? 23.624  -21.227 3.543   1.00 37.88  ? 221 ASP C N   1 
ATOM   8920  C CA  . ASP C 1 221 ? 25.042  -21.569 3.619   1.00 38.54  ? 221 ASP C CA  1 
ATOM   8921  C C   . ASP C 1 221 ? 25.782  -20.523 4.458   1.00 36.99  ? 221 ASP C C   1 
ATOM   8922  O O   . ASP C 1 221 ? 25.513  -19.332 4.368   1.00 31.42  ? 221 ASP C O   1 
ATOM   8923  C CB  . ASP C 1 221 ? 25.693  -21.648 2.237   1.00 48.57  ? 221 ASP C CB  1 
ATOM   8924  C CG  . ASP C 1 221 ? 25.254  -22.831 1.388   1.00 56.62  ? 221 ASP C CG  1 
ATOM   8925  O OD1 . ASP C 1 221 ? 24.603  -23.750 1.932   1.00 56.81  ? 221 ASP C OD1 1 
ATOM   8926  O OD2 . ASP C 1 221 ? 25.561  -22.816 0.176   1.00 74.62  ? 221 ASP C OD2 1 
ATOM   8927  N N   . PHE C 1 222 ? 26.777  -20.974 5.219   1.00 38.74  ? 222 PHE C N   1 
ATOM   8928  C CA  . PHE C 1 222 ? 27.578  -20.129 6.093   1.00 35.64  ? 222 PHE C CA  1 
ATOM   8929  C C   . PHE C 1 222 ? 28.233  -18.979 5.335   1.00 30.65  ? 222 PHE C C   1 
ATOM   8930  O O   . PHE C 1 222 ? 28.200  -17.848 5.794   1.00 31.75  ? 222 PHE C O   1 
ATOM   8931  C CB  . PHE C 1 222 ? 28.633  -20.990 6.804   1.00 40.43  ? 222 PHE C CB  1 
ATOM   8932  C CG  . PHE C 1 222 ? 29.676  -20.226 7.589   1.00 41.76  ? 222 PHE C CG  1 
ATOM   8933  C CD1 . PHE C 1 222 ? 29.358  -19.600 8.783   1.00 45.70  ? 222 PHE C CD1 1 
ATOM   8934  C CD2 . PHE C 1 222 ? 30.987  -20.150 7.132   1.00 45.66  ? 222 PHE C CD2 1 
ATOM   8935  C CE1 . PHE C 1 222 ? 30.324  -18.907 9.501   1.00 46.11  ? 222 PHE C CE1 1 
ATOM   8936  C CE2 . PHE C 1 222 ? 31.949  -19.443 7.839   1.00 47.13  ? 222 PHE C CE2 1 
ATOM   8937  C CZ  . PHE C 1 222 ? 31.614  -18.822 9.018   1.00 48.01  ? 222 PHE C CZ  1 
ATOM   8938  N N   . GLU C 1 223 ? 28.841  -19.274 4.187   1.00 34.32  ? 223 GLU C N   1 
ATOM   8939  C CA  . GLU C 1 223 ? 29.514  -18.274 3.382   1.00 35.85  ? 223 GLU C CA  1 
ATOM   8940  C C   . GLU C 1 223 ? 28.509  -17.219 2.919   1.00 33.89  ? 223 GLU C C   1 
ATOM   8941  O O   . GLU C 1 223 ? 28.916  -16.094 2.691   1.00 28.92  ? 223 GLU C O   1 
ATOM   8942  C CB  . GLU C 1 223 ? 30.167  -18.873 2.125   1.00 44.67  ? 223 GLU C CB  1 
ATOM   8943  C CG  . GLU C 1 223 ? 31.389  -19.755 2.372   1.00 52.60  ? 223 GLU C CG  1 
ATOM   8944  C CD  . GLU C 1 223 ? 32.127  -20.242 1.121   1.00 67.56  ? 223 GLU C CD  1 
ATOM   8945  O OE1 . GLU C 1 223 ? 33.166  -20.935 1.288   1.00 81.23  ? 223 GLU C OE1 1 
ATOM   8946  O OE2 . GLU C 1 223 ? 31.699  -19.923 -0.036  1.00 60.08  ? 223 GLU C OE2 1 
ATOM   8947  N N   . VAL C 1 224 ? 27.219  -17.560 2.767   1.00 31.04  ? 224 VAL C N   1 
ATOM   8948  C CA  . VAL C 1 224 ? 26.252  -16.562 2.338   1.00 30.21  ? 224 VAL C CA  1 
ATOM   8949  C C   . VAL C 1 224 ? 25.939  -15.642 3.509   1.00 26.08  ? 224 VAL C C   1 
ATOM   8950  O O   . VAL C 1 224 ? 25.810  -14.425 3.337   1.00 30.34  ? 224 VAL C O   1 
ATOM   8951  C CB  . VAL C 1 224 ? 24.973  -17.167 1.736   1.00 31.46  ? 224 VAL C CB  1 
ATOM   8952  C CG1 . VAL C 1 224 ? 23.902  -16.109 1.477   1.00 35.46  ? 224 VAL C CG1 1 
ATOM   8953  C CG2 . VAL C 1 224 ? 25.289  -17.878 0.454   1.00 34.70  ? 224 VAL C CG2 1 
ATOM   8954  N N   . TYR C 1 225 ? 25.827  -16.219 4.694   1.00 28.39  ? 225 TYR C N   1 
ATOM   8955  C CA  . TYR C 1 225 ? 25.626  -15.415 5.886   1.00 25.99  ? 225 TYR C CA  1 
ATOM   8956  C C   . TYR C 1 225 ? 26.769  -14.413 6.055   1.00 25.56  ? 225 TYR C C   1 
ATOM   8957  O O   . TYR C 1 225 ? 26.532  -13.244 6.297   1.00 26.93  ? 225 TYR C O   1 
ATOM   8958  C CB  . TYR C 1 225 ? 25.481  -16.305 7.115   1.00 26.57  ? 225 TYR C CB  1 
ATOM   8959  C CG  . TYR C 1 225 ? 24.233  -17.138 7.248   1.00 30.27  ? 225 TYR C CG  1 
ATOM   8960  C CD1 . TYR C 1 225 ? 23.156  -17.070 6.373   1.00 33.04  ? 225 TYR C CD1 1 
ATOM   8961  C CD2 . TYR C 1 225 ? 24.149  -18.044 8.291   1.00 34.59  ? 225 TYR C CD2 1 
ATOM   8962  C CE1 . TYR C 1 225 ? 22.026  -17.863 6.561   1.00 32.57  ? 225 TYR C CE1 1 
ATOM   8963  C CE2 . TYR C 1 225 ? 23.035  -18.842 8.489   1.00 31.95  ? 225 TYR C CE2 1 
ATOM   8964  C CZ  . TYR C 1 225 ? 21.965  -18.740 7.633   1.00 32.35  ? 225 TYR C CZ  1 
ATOM   8965  O OH  . TYR C 1 225 ? 20.894  -19.553 7.904   1.00 34.32  ? 225 TYR C OH  1 
ATOM   8966  N N   . GLU C 1 226 ? 28.009  -14.883 5.894   1.00 31.58  ? 226 GLU C N   1 
ATOM   8967  C CA  . GLU C 1 226 ? 29.216  -14.057 5.942   1.00 31.92  ? 226 GLU C CA  1 
ATOM   8968  C C   . GLU C 1 226 ? 29.208  -12.983 4.850   1.00 28.78  ? 226 GLU C C   1 
ATOM   8969  O O   . GLU C 1 226 ? 29.548  -11.832 5.110   1.00 28.84  ? 226 GLU C O   1 
ATOM   8970  C CB  . GLU C 1 226 ? 30.449  -14.967 5.843   1.00 30.18  ? 226 GLU C CB  1 
ATOM   8971  C CG  . GLU C 1 226 ? 30.662  -15.808 7.084   1.00 30.89  ? 226 GLU C CG  1 
ATOM   8972  C CD  . GLU C 1 226 ? 31.165  -15.007 8.274   1.00 34.58  ? 226 GLU C CD  1 
ATOM   8973  O OE1 . GLU C 1 226 ? 30.349  -14.631 9.168   1.00 35.98  ? 226 GLU C OE1 1 
ATOM   8974  O OE2 . GLU C 1 226 ? 32.376  -14.688 8.276   1.00 33.87  ? 226 GLU C OE2 1 
ATOM   8975  N N   . LEU C 1 227 ? 28.778  -13.314 3.631   1.00 27.11  ? 227 LEU C N   1 
ATOM   8976  C CA  . LEU C 1 227 ? 28.688  -12.278 2.599   1.00 27.58  ? 227 LEU C CA  1 
ATOM   8977  C C   . LEU C 1 227 ? 27.674  -11.189 2.957   1.00 28.32  ? 227 LEU C C   1 
ATOM   8978  O O   . LEU C 1 227 ? 27.943  -10.005 2.780   1.00 30.34  ? 227 LEU C O   1 
ATOM   8979  C CB  . LEU C 1 227 ? 28.331  -12.899 1.252   1.00 25.69  ? 227 LEU C CB  1 
ATOM   8980  C CG  . LEU C 1 227 ? 27.972  -11.902 0.150   1.00 27.98  ? 227 LEU C CG  1 
ATOM   8981  C CD1 . LEU C 1 227 ? 29.179  -11.094 -0.305  1.00 31.81  ? 227 LEU C CD1 1 
ATOM   8982  C CD2 . LEU C 1 227 ? 27.365  -12.642 -1.018  1.00 32.27  ? 227 LEU C CD2 1 
ATOM   8983  N N   . PHE C 1 228 ? 26.527  -11.590 3.512   1.00 27.37  ? 228 PHE C N   1 
ATOM   8984  C CA  . PHE C 1 228 ? 25.503  -10.627 3.890   1.00 28.86  ? 228 PHE C CA  1 
ATOM   8985  C C   . PHE C 1 228 ? 25.988  -9.725  5.024   1.00 25.34  ? 228 PHE C C   1 
ATOM   8986  O O   . PHE C 1 228 ? 25.727  -8.525  5.026   1.00 26.93  ? 228 PHE C O   1 
ATOM   8987  C CB  . PHE C 1 228 ? 24.217  -11.373 4.279   1.00 28.91  ? 228 PHE C CB  1 
ATOM   8988  C CG  . PHE C 1 228 ? 23.282  -11.623 3.123   1.00 28.10  ? 228 PHE C CG  1 
ATOM   8989  C CD1 . PHE C 1 228 ? 23.720  -12.282 1.987   1.00 30.82  ? 228 PHE C CD1 1 
ATOM   8990  C CD2 . PHE C 1 228 ? 21.958  -11.195 3.177   1.00 27.13  ? 228 PHE C CD2 1 
ATOM   8991  C CE1 . PHE C 1 228 ? 22.873  -12.478 0.900   1.00 33.83  ? 228 PHE C CE1 1 
ATOM   8992  C CE2 . PHE C 1 228 ? 21.103  -11.431 2.107   1.00 28.95  ? 228 PHE C CE2 1 
ATOM   8993  C CZ  . PHE C 1 228 ? 21.567  -12.024 0.961   1.00 30.70  ? 228 PHE C CZ  1 
ATOM   8994  N N   . ARG C 1 229 ? 26.682  -10.307 6.008   1.00 26.11  ? 229 ARG C N   1 
ATOM   8995  C CA  . ARG C 1 229 ? 27.191  -9.533  7.134   1.00 26.67  ? 229 ARG C CA  1 
ATOM   8996  C C   . ARG C 1 229 ? 28.177  -8.494  6.596   1.00 23.77  ? 229 ARG C C   1 
ATOM   8997  O O   . ARG C 1 229 ? 28.093  -7.309  6.933   1.00 26.59  ? 229 ARG C O   1 
ATOM   8998  C CB  . ARG C 1 229 ? 27.872  -10.447 8.168   1.00 26.31  ? 229 ARG C CB  1 
ATOM   8999  C CG  . ARG C 1 229 ? 26.936  -11.339 8.951   1.00 27.64  ? 229 ARG C CG  1 
ATOM   9000  C CD  . ARG C 1 229 ? 27.599  -12.550 9.577   1.00 29.80  ? 229 ARG C CD  1 
ATOM   9001  N NE  . ARG C 1 229 ? 26.604  -13.415 10.200  1.00 30.59  ? 229 ARG C NE  1 
ATOM   9002  C CZ  . ARG C 1 229 ? 26.693  -14.733 10.311  1.00 30.83  ? 229 ARG C CZ  1 
ATOM   9003  N NH1 . ARG C 1 229 ? 27.728  -15.387 9.839   1.00 34.40  ? 229 ARG C NH1 1 
ATOM   9004  N NH2 . ARG C 1 229 ? 25.775  -15.395 10.972  1.00 36.29  ? 229 ARG C NH2 1 
ATOM   9005  N N   . LEU C 1 230 ? 29.047  -8.916  5.672   1.00 26.58  ? 230 LEU C N   1 
ATOM   9006  C CA  . LEU C 1 230 ? 30.021  -7.996  5.092   1.00 27.19  ? 230 LEU C CA  1 
ATOM   9007  C C   . LEU C 1 230 ? 29.350  -6.944  4.218   1.00 26.62  ? 230 LEU C C   1 
ATOM   9008  O O   . LEU C 1 230 ? 29.695  -5.766  4.278   1.00 29.10  ? 230 LEU C O   1 
ATOM   9009  C CB  . LEU C 1 230 ? 31.060  -8.761  4.266   1.00 30.08  ? 230 LEU C CB  1 
ATOM   9010  C CG  . LEU C 1 230 ? 32.039  -7.849  3.521   1.00 30.40  ? 230 LEU C CG  1 
ATOM   9011  C CD1 . LEU C 1 230 ? 32.865  -7.020  4.512   1.00 29.51  ? 230 LEU C CD1 1 
ATOM   9012  C CD2 . LEU C 1 230 ? 32.962  -8.653  2.606   1.00 30.48  ? 230 LEU C CD2 1 
ATOM   9013  N N   . TYR C 1 231 ? 28.426  -7.373  3.356   1.00 27.43  ? 231 TYR C N   1 
ATOM   9014  C CA  . TYR C 1 231 ? 27.670  -6.465  2.492   1.00 27.42  ? 231 TYR C CA  1 
ATOM   9015  C C   . TYR C 1 231 ? 26.982  -5.362  3.324   1.00 28.05  ? 231 TYR C C   1 
ATOM   9016  O O   . TYR C 1 231 ? 27.075  -4.168  3.010   1.00 27.96  ? 231 TYR C O   1 
ATOM   9017  C CB  . TYR C 1 231 ? 26.691  -7.276  1.621   1.00 30.42  ? 231 TYR C CB  1 
ATOM   9018  C CG  . TYR C 1 231 ? 25.892  -6.426  0.667   1.00 31.35  ? 231 TYR C CG  1 
ATOM   9019  C CD1 . TYR C 1 231 ? 24.828  -5.674  1.133   1.00 37.54  ? 231 TYR C CD1 1 
ATOM   9020  C CD2 . TYR C 1 231 ? 26.279  -6.244  -0.643  1.00 35.57  ? 231 TYR C CD2 1 
ATOM   9021  C CE1 . TYR C 1 231 ? 24.141  -4.788  0.317   1.00 39.03  ? 231 TYR C CE1 1 
ATOM   9022  C CE2 . TYR C 1 231 ? 25.578  -5.387  -1.487  1.00 38.04  ? 231 TYR C CE2 1 
ATOM   9023  C CZ  . TYR C 1 231 ? 24.505  -4.658  -1.007  1.00 35.70  ? 231 TYR C CZ  1 
ATOM   9024  O OH  . TYR C 1 231 ? 23.798  -3.760  -1.776  1.00 34.06  ? 231 TYR C OH  1 
ATOM   9025  N N   . MET C 1 232 ? 26.281  -5.760  4.391   1.00 28.46  ? 232 MET C N   1 
ATOM   9026  C CA  . MET C 1 232 ? 25.497  -4.838  5.212   1.00 26.83  ? 232 MET C CA  1 
ATOM   9027  C C   . MET C 1 232 ? 26.425  -3.874  5.957   1.00 30.12  ? 232 MET C C   1 
ATOM   9028  O O   . MET C 1 232 ? 26.075  -2.715  6.144   1.00 26.33  ? 232 MET C O   1 
ATOM   9029  C CB  . MET C 1 232 ? 24.647  -5.580  6.252   1.00 27.91  ? 232 MET C CB  1 
ATOM   9030  C CG  . MET C 1 232 ? 23.479  -6.383  5.648   1.00 33.44  ? 232 MET C CG  1 
ATOM   9031  S SD  . MET C 1 232 ? 22.404  -5.370  4.640   1.00 37.15  ? 232 MET C SD  1 
ATOM   9032  C CE  . MET C 1 232 ? 21.609  -6.636  3.648   1.00 43.43  ? 232 MET C CE  1 
ATOM   9033  N N   . PHE C 1 233 ? 27.585  -4.381  6.398   1.00 31.14  ? 233 PHE C N   1 
ATOM   9034  C CA  . PHE C 1 233 ? 28.644  -3.568  6.996   1.00 29.64  ? 233 PHE C CA  1 
ATOM   9035  C C   . PHE C 1 233 ? 29.180  -2.511  6.022   1.00 25.13  ? 233 PHE C C   1 
ATOM   9036  O O   . PHE C 1 233 ? 29.220  -1.316  6.345   1.00 28.06  ? 233 PHE C O   1 
ATOM   9037  C CB  . PHE C 1 233 ? 29.738  -4.498  7.555   1.00 31.23  ? 233 PHE C CB  1 
ATOM   9038  C CG  . PHE C 1 233 ? 31.030  -3.818  7.940   1.00 31.06  ? 233 PHE C CG  1 
ATOM   9039  C CD1 . PHE C 1 233 ? 31.201  -3.244  9.189   1.00 34.88  ? 233 PHE C CD1 1 
ATOM   9040  C CD2 . PHE C 1 233 ? 32.088  -3.751  7.037   1.00 33.80  ? 233 PHE C CD2 1 
ATOM   9041  C CE1 . PHE C 1 233 ? 32.390  -2.598  9.511   1.00 35.84  ? 233 PHE C CE1 1 
ATOM   9042  C CE2 . PHE C 1 233 ? 33.281  -3.127  7.370   1.00 35.00  ? 233 PHE C CE2 1 
ATOM   9043  C CZ  . PHE C 1 233 ? 33.417  -2.521  8.592   1.00 34.03  ? 233 PHE C CZ  1 
ATOM   9044  N N   . LEU C 1 234 ? 29.508  -2.891  4.790   1.00 25.46  ? 234 LEU C N   1 
ATOM   9045  C CA  . LEU C 1 234 ? 30.189  -1.978  3.856   1.00 26.88  ? 234 LEU C CA  1 
ATOM   9046  C C   . LEU C 1 234 ? 29.283  -0.882  3.304   1.00 30.75  ? 234 LEU C C   1 
ATOM   9047  O O   . LEU C 1 234 ? 29.757  0.228   2.996   1.00 28.95  ? 234 LEU C O   1 
ATOM   9048  C CB  . LEU C 1 234 ? 30.730  -2.779  2.672   1.00 29.08  ? 234 LEU C CB  1 
ATOM   9049  C CG  . LEU C 1 234 ? 31.850  -3.780  2.963   1.00 29.08  ? 234 LEU C CG  1 
ATOM   9050  C CD1 . LEU C 1 234 ? 32.208  -4.520  1.676   1.00 29.21  ? 234 LEU C CD1 1 
ATOM   9051  C CD2 . LEU C 1 234 ? 33.067  -3.098  3.518   1.00 30.38  ? 234 LEU C CD2 1 
ATOM   9052  N N   . HIS C 1 235 ? 28.001  -1.217  3.088   1.00 27.11  ? 235 HIS C N   1 
ATOM   9053  C CA  . HIS C 1 235 ? 27.059  -0.302  2.456   1.00 25.75  ? 235 HIS C CA  1 
ATOM   9054  C C   . HIS C 1 235 ? 26.328  0.573   3.487   1.00 24.64  ? 235 HIS C C   1 
ATOM   9055  O O   . HIS C 1 235 ? 25.456  1.356   3.118   1.00 28.02  ? 235 HIS C O   1 
ATOM   9056  C CB  . HIS C 1 235 ? 26.100  -1.071  1.546   1.00 28.09  ? 235 HIS C CB  1 
ATOM   9057  C CG  . HIS C 1 235 ? 26.714  -1.695  0.331   1.00 28.47  ? 235 HIS C CG  1 
ATOM   9058  N ND1 . HIS C 1 235 ? 27.368  -2.906  0.351   1.00 30.05  ? 235 HIS C ND1 1 
ATOM   9059  C CD2 . HIS C 1 235 ? 26.815  -1.220  -0.942  1.00 30.70  ? 235 HIS C CD2 1 
ATOM   9060  C CE1 . HIS C 1 235 ? 27.830  -3.171  -0.875  1.00 34.46  ? 235 HIS C CE1 1 
ATOM   9061  N NE2 . HIS C 1 235 ? 27.491  -2.173  -1.678  1.00 36.35  ? 235 HIS C NE2 1 
ATOM   9062  N N   . SER C 1 236 ? 26.699  0.482   4.763   1.00 26.00  ? 236 SER C N   1 
ATOM   9063  C CA  . SER C 1 236 ? 25.950  1.083   5.871   1.00 28.34  ? 236 SER C CA  1 
ATOM   9064  C C   . SER C 1 236 ? 25.828  2.605   5.786   1.00 29.44  ? 236 SER C C   1 
ATOM   9065  O O   . SER C 1 236 ? 24.778  3.157   6.075   1.00 31.96  ? 236 SER C O   1 
ATOM   9066  C CB  . SER C 1 236 ? 26.548  0.662   7.178   1.00 29.89  ? 236 SER C CB  1 
ATOM   9067  O OG  . SER C 1 236 ? 27.890  1.109   7.232   1.00 33.98  ? 236 SER C OG  1 
ATOM   9068  N N   . ASP C 1 237 ? 26.897  3.289   5.384   1.00 27.44  ? 237 ASP C N   1 
ATOM   9069  C CA  . ASP C 1 237 ? 26.989  4.723   5.521   1.00 31.24  ? 237 ASP C CA  1 
ATOM   9070  C C   . ASP C 1 237 ? 28.137  5.213   4.647   1.00 31.07  ? 237 ASP C C   1 
ATOM   9071  O O   . ASP C 1 237 ? 29.130  4.494   4.521   1.00 33.58  ? 237 ASP C O   1 
ATOM   9072  C CB  . ASP C 1 237 ? 27.275  5.113   6.971   1.00 32.70  ? 237 ASP C CB  1 
ATOM   9073  C CG  . ASP C 1 237 ? 26.881  6.533   7.385   1.00 42.59  ? 237 ASP C CG  1 
ATOM   9074  O OD1 . ASP C 1 237 ? 25.743  6.965   7.028   1.00 44.14  ? 237 ASP C OD1 1 
ATOM   9075  O OD2 . ASP C 1 237 ? 27.673  7.177   8.155   1.00 41.73  ? 237 ASP C OD2 1 
ATOM   9076  N N   . HIS C 1 238 ? 27.988  6.430   4.106   1.00 30.40  ? 238 HIS C N   1 
ATOM   9077  C CA  . HIS C 1 238 ? 28.976  7.076   3.244   1.00 31.39  ? 238 HIS C CA  1 
ATOM   9078  C C   . HIS C 1 238 ? 28.771  8.590   3.271   1.00 30.35  ? 238 HIS C C   1 
ATOM   9079  O O   . HIS C 1 238 ? 28.393  9.201   2.263   1.00 30.69  ? 238 HIS C O   1 
ATOM   9080  C CB  . HIS C 1 238 ? 28.873  6.578   1.798   1.00 33.48  ? 238 HIS C CB  1 
ATOM   9081  C CG  . HIS C 1 238 ? 30.189  6.550   1.084   1.00 34.72  ? 238 HIS C CG  1 
ATOM   9082  N ND1 . HIS C 1 238 ? 30.442  7.158   -0.121  1.00 38.93  ? 238 HIS C ND1 1 
ATOM   9083  C CD2 . HIS C 1 238 ? 31.306  5.900   1.413   1.00 32.74  ? 238 HIS C CD2 1 
ATOM   9084  C CE1 . HIS C 1 238 ? 31.690  6.903   -0.465  1.00 36.07  ? 238 HIS C CE1 1 
ATOM   9085  N NE2 . HIS C 1 238 ? 32.220  6.127   0.454   1.00 32.97  ? 238 HIS C NE2 1 
ATOM   9086  N N   . GLU C 1 239 ? 28.926  9.169   4.469   1.00 30.30  ? 239 GLU C N   1 
ATOM   9087  C CA  . GLU C 1 239 ? 28.736  10.595  4.678   1.00 34.65  ? 239 GLU C CA  1 
ATOM   9088  C C   . GLU C 1 239 ? 27.258  10.982  4.563   1.00 37.35  ? 239 GLU C C   1 
ATOM   9089  O O   . GLU C 1 239 ? 26.371  10.138  4.452   1.00 35.39  ? 239 GLU C O   1 
ATOM   9090  C CB  . GLU C 1 239 ? 29.600  11.383  3.674   1.00 38.62  ? 239 GLU C CB  1 
ATOM   9091  C CG  . GLU C 1 239 ? 30.880  11.875  4.280   1.00 45.90  ? 239 GLU C CG  1 
ATOM   9092  C CD  . GLU C 1 239 ? 31.733  12.850  3.462   1.00 41.18  ? 239 GLU C CD  1 
ATOM   9093  O OE1 . GLU C 1 239 ? 32.906  12.995  3.834   1.00 47.18  ? 239 GLU C OE1 1 
ATOM   9094  O OE2 . GLU C 1 239 ? 31.232  13.477  2.488   1.00 43.78  ? 239 GLU C OE2 1 
ATOM   9095  N N   . GLY C 1 240 ? 27.008  12.294  4.522   1.00 35.23  ? 240 GLY C N   1 
ATOM   9096  C CA  . GLY C 1 240 ? 25.668  12.824  4.638   1.00 31.99  ? 240 GLY C CA  1 
ATOM   9097  C C   . GLY C 1 240 ? 25.119  13.327  3.324   1.00 31.56  ? 240 GLY C C   1 
ATOM   9098  O O   . GLY C 1 240 ? 23.933  13.636  3.279   1.00 32.78  ? 240 GLY C O   1 
ATOM   9099  N N   . GLY C 1 241 ? 25.990  13.458  2.300   1.00 27.29  ? 241 GLY C N   1 
ATOM   9100  C CA  . GLY C 1 241 ? 25.663  14.194  1.089   1.00 28.91  ? 241 GLY C CA  1 
ATOM   9101  C C   . GLY C 1 241 ? 25.153  13.374  -0.101  1.00 29.90  ? 241 GLY C C   1 
ATOM   9102  O O   . GLY C 1 241 ? 24.599  13.937  -1.058  1.00 31.92  ? 241 GLY C O   1 
ATOM   9103  N N   . ASN C 1 242 ? 25.274  12.053  -0.031  1.00 31.15  ? 242 ASN C N   1 
ATOM   9104  C CA  . ASN C 1 242 ? 24.684  11.173  -1.042  1.00 28.69  ? 242 ASN C CA  1 
ATOM   9105  C C   . ASN C 1 242 ? 23.165  11.337  -0.984  1.00 31.03  ? 242 ASN C C   1 
ATOM   9106  O O   . ASN C 1 242 ? 22.631  11.788  0.015   1.00 27.16  ? 242 ASN C O   1 
ATOM   9107  C CB  . ASN C 1 242 ? 25.225  9.747   -0.869  1.00 29.69  ? 242 ASN C CB  1 
ATOM   9108  C CG  . ASN C 1 242 ? 24.704  8.985   0.341   1.00 31.79  ? 242 ASN C CG  1 
ATOM   9109  O OD1 . ASN C 1 242 ? 23.604  8.441   0.338   1.00 35.88  ? 242 ASN C OD1 1 
ATOM   9110  N ND2 . ASN C 1 242 ? 25.462  8.947   1.414   1.00 36.07  ? 242 ASN C ND2 1 
ATOM   9111  N N   . VAL C 1 243 ? 22.461  11.069  -2.095  1.00 32.40  ? 243 VAL C N   1 
ATOM   9112  C CA  . VAL C 1 243 ? 21.074  11.465  -2.243  1.00 33.00  ? 243 VAL C CA  1 
ATOM   9113  C C   . VAL C 1 243 ? 20.180  10.807  -1.188  1.00 29.82  ? 243 VAL C C   1 
ATOM   9114  O O   . VAL C 1 243 ? 19.240  11.442  -0.708  1.00 28.19  ? 243 VAL C O   1 
ATOM   9115  C CB  . VAL C 1 243 ? 20.571  11.160  -3.665  1.00 33.52  ? 243 VAL C CB  1 
ATOM   9116  C CG1 . VAL C 1 243 ? 19.060  11.227  -3.753  1.00 36.59  ? 243 VAL C CG1 1 
ATOM   9117  C CG2 . VAL C 1 243 ? 21.202  12.080  -4.684  1.00 33.57  ? 243 VAL C CG2 1 
ATOM   9118  N N   . SER C 1 244 ? 20.427  9.541   -0.871  1.00 28.12  ? 244 SER C N   1 
ATOM   9119  C CA  . SER C 1 244 ? 19.587  8.832   0.077   1.00 31.52  ? 244 SER C CA  1 
ATOM   9120  C C   . SER C 1 244 ? 19.791  9.360   1.497   1.00 28.71  ? 244 SER C C   1 
ATOM   9121  O O   . SER C 1 244 ? 18.822  9.683   2.186   1.00 29.86  ? 244 SER C O   1 
ATOM   9122  C CB  . SER C 1 244 ? 19.805  7.328   -0.021  1.00 32.79  ? 244 SER C CB  1 
ATOM   9123  O OG  . SER C 1 244 ? 21.120  6.966   0.311   1.00 36.45  ? 244 SER C OG  1 
ATOM   9124  N N   . ALA C 1 245 ? 21.053  9.538   1.907   1.00 29.12  ? 245 ALA C N   1 
ATOM   9125  C CA  . ALA C 1 245 ? 21.377  10.074  3.226   1.00 30.26  ? 245 ALA C CA  1 
ATOM   9126  C C   . ALA C 1 245 ? 20.850  11.499  3.362   1.00 28.52  ? 245 ALA C C   1 
ATOM   9127  O O   . ALA C 1 245 ? 20.287  11.861  4.370   1.00 29.03  ? 245 ALA C O   1 
ATOM   9128  C CB  . ALA C 1 245 ? 22.855  10.001  3.522   1.00 31.04  ? 245 ALA C CB  1 
ATOM   9129  N N   . HIS C 1 246 ? 20.989  12.274  2.318   1.00 28.31  ? 246 HIS C N   1 
ATOM   9130  C CA  . HIS C 1 246 ? 20.580  13.652  2.315   1.00 30.50  ? 246 HIS C CA  1 
ATOM   9131  C C   . HIS C 1 246 ? 19.065  13.766  2.342   1.00 27.24  ? 246 HIS C C   1 
ATOM   9132  O O   . HIS C 1 246 ? 18.548  14.617  3.046   1.00 26.26  ? 246 HIS C O   1 
ATOM   9133  C CB  . HIS C 1 246 ? 21.175  14.357  1.091   1.00 31.54  ? 246 HIS C CB  1 
ATOM   9134  C CG  . HIS C 1 246 ? 20.912  15.819  1.080   1.00 30.80  ? 246 HIS C CG  1 
ATOM   9135  N ND1 . HIS C 1 246 ? 21.049  16.615  -0.035  1.00 31.93  ? 246 HIS C ND1 1 
ATOM   9136  C CD2 . HIS C 1 246 ? 20.440  16.625  2.069   1.00 30.92  ? 246 HIS C CD2 1 
ATOM   9137  C CE1 . HIS C 1 246 ? 20.649  17.851  0.277   1.00 33.73  ? 246 HIS C CE1 1 
ATOM   9138  N NE2 . HIS C 1 246 ? 20.262  17.871  1.540   1.00 29.83  ? 246 HIS C NE2 1 
ATOM   9139  N N   . THR C 1 247 ? 18.363  12.951  1.533   1.00 24.99  ? 247 THR C N   1 
ATOM   9140  C CA  . THR C 1 247 ? 16.912  12.922  1.532   1.00 23.80  ? 247 THR C CA  1 
ATOM   9141  C C   . THR C 1 247 ? 16.421  12.616  2.949   1.00 24.03  ? 247 THR C C   1 
ATOM   9142  O O   . THR C 1 247 ? 15.512  13.284  3.439   1.00 24.43  ? 247 THR C O   1 
ATOM   9143  C CB  . THR C 1 247 ? 16.349  11.934  0.495   1.00 25.69  ? 247 THR C CB  1 
ATOM   9144  O OG1 . THR C 1 247 ? 16.871  12.296  -0.793  1.00 27.33  ? 247 THR C OG1 1 
ATOM   9145  C CG2 . THR C 1 247 ? 14.834  11.914  0.478   1.00 24.97  ? 247 THR C CG2 1 
ATOM   9146  N N   . ASN C 1 248 ? 17.017  11.615  3.599   1.00 26.50  ? 248 ASN C N   1 
ATOM   9147  C CA  . ASN C 1 248 ? 16.662  11.231  4.949   1.00 26.95  ? 248 ASN C CA  1 
ATOM   9148  C C   . ASN C 1 248 ? 16.819  12.432  5.909   1.00 30.49  ? 248 ASN C C   1 
ATOM   9149  O O   . ASN C 1 248 ? 15.922  12.741  6.689   1.00 26.83  ? 248 ASN C O   1 
ATOM   9150  C CB  . ASN C 1 248 ? 17.466  10.010  5.384   1.00 25.63  ? 248 ASN C CB  1 
ATOM   9151  C CG  . ASN C 1 248 ? 17.177  9.581   6.804   1.00 27.40  ? 248 ASN C CG  1 
ATOM   9152  O OD1 . ASN C 1 248 ? 18.028  9.647   7.698   1.00 30.03  ? 248 ASN C OD1 1 
ATOM   9153  N ND2 . ASN C 1 248 ? 15.958  9.145   7.018   1.00 27.24  ? 248 ASN C ND2 1 
ATOM   9154  N N   . LEU C 1 249 ? 17.938  13.142  5.841   1.00 26.56  ? 249 LEU C N   1 
ATOM   9155  C CA  . LEU C 1 249 ? 18.177  14.294  6.711   1.00 27.33  ? 249 LEU C CA  1 
ATOM   9156  C C   . LEU C 1 249 ? 17.194  15.419  6.455   1.00 25.74  ? 249 LEU C C   1 
ATOM   9157  O O   . LEU C 1 249 ? 16.717  16.024  7.386   1.00 29.53  ? 249 LEU C O   1 
ATOM   9158  C CB  . LEU C 1 249 ? 19.601  14.797  6.495   1.00 33.69  ? 249 LEU C CB  1 
ATOM   9159  C CG  . LEU C 1 249 ? 20.673  13.919  7.121   1.00 39.98  ? 249 LEU C CG  1 
ATOM   9160  C CD1 . LEU C 1 249 ? 22.052  14.358  6.634   1.00 41.50  ? 249 LEU C CD1 1 
ATOM   9161  C CD2 . LEU C 1 249 ? 20.590  13.982  8.640   1.00 40.93  ? 249 LEU C CD2 1 
ATOM   9162  N N   . LEU C 1 250 ? 16.927  15.706  5.183   1.00 24.39  ? 250 LEU C N   1 
ATOM   9163  C CA  . LEU C 1 250 ? 16.073  16.785  4.781   1.00 27.94  ? 250 LEU C CA  1 
ATOM   9164  C C   . LEU C 1 250 ? 14.641  16.559  5.285   1.00 28.93  ? 250 LEU C C   1 
ATOM   9165  O O   . LEU C 1 250 ? 14.010  17.448  5.862   1.00 28.44  ? 250 LEU C O   1 
ATOM   9166  C CB  . LEU C 1 250 ? 16.179  16.842  3.256   1.00 29.22  ? 250 LEU C CB  1 
ATOM   9167  C CG  . LEU C 1 250 ? 15.234  17.790  2.554   1.00 28.08  ? 250 LEU C CG  1 
ATOM   9168  C CD1 . LEU C 1 250 ? 15.263  19.170  3.168   1.00 35.08  ? 250 LEU C CD1 1 
ATOM   9169  C CD2 . LEU C 1 250 ? 15.601  17.880  1.085   1.00 30.87  ? 250 LEU C CD2 1 
ATOM   9170  N N   . VAL C 1 251 ? 14.126  15.335  5.153   1.00 28.48  ? 251 VAL C N   1 
ATOM   9171  C CA  . VAL C 1 251 ? 12.769  15.064  5.591   1.00 23.58  ? 251 VAL C CA  1 
ATOM   9172  C C   . VAL C 1 251 ? 12.740  15.009  7.120   1.00 24.02  ? 251 VAL C C   1 
ATOM   9173  O O   . VAL C 1 251 ? 11.817  15.536  7.729   1.00 29.50  ? 251 VAL C O   1 
ATOM   9174  C CB  . VAL C 1 251 ? 12.238  13.803  4.908   1.00 22.62  ? 251 VAL C CB  1 
ATOM   9175  C CG1 . VAL C 1 251 ? 10.902  13.344  5.503   1.00 23.09  ? 251 VAL C CG1 1 
ATOM   9176  C CG2 . VAL C 1 251 ? 12.129  14.031  3.398   1.00 24.22  ? 251 VAL C CG2 1 
ATOM   9177  N N   . ASN C 1 252 ? 13.721  14.330  7.738   1.00 27.38  ? 252 ASN C N   1 
ATOM   9178  C CA  . ASN C 1 252 ? 13.911  14.353  9.177   1.00 27.24  ? 252 ASN C CA  1 
ATOM   9179  C C   . ASN C 1 252 ? 13.857  15.787  9.727   1.00 32.12  ? 252 ASN C C   1 
ATOM   9180  O O   . ASN C 1 252 ? 13.322  16.009  10.828  1.00 29.51  ? 252 ASN C O   1 
ATOM   9181  C CB  . ASN C 1 252 ? 15.219  13.670  9.580   1.00 27.92  ? 252 ASN C CB  1 
ATOM   9182  C CG  . ASN C 1 252 ? 15.532  13.764  11.065  1.00 30.09  ? 252 ASN C CG  1 
ATOM   9183  O OD1 . ASN C 1 252 ? 16.266  14.658  11.533  1.00 27.39  ? 252 ASN C OD1 1 
ATOM   9184  N ND2 . ASN C 1 252 ? 14.955  12.853  11.825  1.00 26.08  ? 252 ASN C ND2 1 
ATOM   9185  N N   . SER C 1 253 ? 14.417  16.756  8.989   1.00 26.89  ? 253 SER C N   1 
ATOM   9186  C CA  . SER C 1 253 ? 14.620  18.100  9.514   1.00 28.56  ? 253 SER C CA  1 
ATOM   9187  C C   . SER C 1 253 ? 13.268  18.803  9.705   1.00 32.00  ? 253 SER C C   1 
ATOM   9188  O O   . SER C 1 253 ? 13.184  19.802  10.412  1.00 29.25  ? 253 SER C O   1 
ATOM   9189  C CB  . SER C 1 253 ? 15.554  18.938  8.623   1.00 23.71  ? 253 SER C CB  1 
ATOM   9190  O OG  . SER C 1 253 ? 14.836  19.527  7.524   1.00 25.95  ? 253 SER C OG  1 
ATOM   9191  N N   . ALA C 1 254 ? 12.207  18.297  9.068   1.00 28.66  ? 254 ALA C N   1 
ATOM   9192  C CA  . ALA C 1 254 ? 10.874  18.842  9.239   1.00 29.35  ? 254 ALA C CA  1 
ATOM   9193  C C   . ALA C 1 254 ? 10.107  18.165  10.376  1.00 25.90  ? 254 ALA C C   1 
ATOM   9194  O O   . ALA C 1 254 ? 8.925   18.438  10.544  1.00 24.23  ? 254 ALA C O   1 
ATOM   9195  C CB  . ALA C 1 254 ? 10.108  18.713  7.949   1.00 30.33  ? 254 ALA C CB  1 
ATOM   9196  N N   . TYR C 1 255 ? 10.780  17.302  11.115  1.00 26.56  ? 255 TYR C N   1 
ATOM   9197  C CA  . TYR C 1 255 ? 10.263  16.479  12.191  1.00 30.24  ? 255 TYR C CA  1 
ATOM   9198  C C   . TYR C 1 255 ? 9.420   15.311  11.668  1.00 31.33  ? 255 TYR C C   1 
ATOM   9199  O O   . TYR C 1 255 ? 8.648   14.728  12.421  1.00 27.54  ? 255 TYR C O   1 
ATOM   9200  C CB  . TYR C 1 255 ? 9.501   17.294  13.244  1.00 34.91  ? 255 TYR C CB  1 
ATOM   9201  C CG  . TYR C 1 255 ? 10.316  18.169  14.187  1.00 37.82  ? 255 TYR C CG  1 
ATOM   9202  C CD1 . TYR C 1 255 ? 11.707  18.273  14.139  1.00 37.31  ? 255 TYR C CD1 1 
ATOM   9203  C CD2 . TYR C 1 255 ? 9.665   18.921  15.154  1.00 42.42  ? 255 TYR C CD2 1 
ATOM   9204  C CE1 . TYR C 1 255 ? 12.420  19.055  15.046  1.00 35.44  ? 255 TYR C CE1 1 
ATOM   9205  C CE2 . TYR C 1 255 ? 10.352  19.738  16.043  1.00 41.23  ? 255 TYR C CE2 1 
ATOM   9206  C CZ  . TYR C 1 255 ? 11.733  19.816  15.975  1.00 42.56  ? 255 TYR C CZ  1 
ATOM   9207  O OH  . TYR C 1 255 ? 12.343  20.643  16.856  1.00 42.43  ? 255 TYR C OH  1 
ATOM   9208  N N   . SER C 1 256 ? 9.615   14.898  10.416  1.00 30.57  ? 256 SER C N   1 
ATOM   9209  C CA  . SER C 1 256 ? 9.001   13.658  9.968   1.00 25.60  ? 256 SER C CA  1 
ATOM   9210  C C   . SER C 1 256 ? 9.746   12.479  10.564  1.00 27.76  ? 256 SER C C   1 
ATOM   9211  O O   . SER C 1 256 ? 10.973  12.497  10.661  1.00 26.84  ? 256 SER C O   1 
ATOM   9212  C CB  . SER C 1 256 ? 8.987   13.556  8.493   1.00 27.94  ? 256 SER C CB  1 
ATOM   9213  O OG  . SER C 1 256 ? 8.181   14.545  7.920   1.00 28.26  ? 256 SER C OG  1 
ATOM   9214  N N   . ASP C 1 257 ? 8.990   11.432  10.945  1.00 26.59  ? 257 ASP C N   1 
ATOM   9215  C CA  . ASP C 1 257 ? 9.573   10.287  11.615  1.00 26.26  ? 257 ASP C CA  1 
ATOM   9216  C C   . ASP C 1 257 ? 10.399  9.440   10.635  1.00 23.22  ? 257 ASP C C   1 
ATOM   9217  O O   . ASP C 1 257 ? 10.414  9.722   9.441   1.00 27.61  ? 257 ASP C O   1 
ATOM   9218  C CB  . ASP C 1 257 ? 8.471   9.483   12.302  1.00 28.39  ? 257 ASP C CB  1 
ATOM   9219  C CG  . ASP C 1 257 ? 7.427   8.992   11.314  1.00 31.23  ? 257 ASP C CG  1 
ATOM   9220  O OD1 . ASP C 1 257 ? 7.795   8.166   10.451  1.00 33.62  ? 257 ASP C OD1 1 
ATOM   9221  O OD2 . ASP C 1 257 ? 6.291   9.521   11.345  1.00 34.98  ? 257 ASP C OD2 1 
ATOM   9222  N N   . ILE C 1 258 ? 11.053  8.394   11.160  1.00 24.90  ? 258 ILE C N   1 
ATOM   9223  C CA  . ILE C 1 258 ? 12.027  7.600   10.435  1.00 24.71  ? 258 ILE C CA  1 
ATOM   9224  C C   . ILE C 1 258 ? 11.355  6.807   9.305   1.00 26.04  ? 258 ILE C C   1 
ATOM   9225  O O   . ILE C 1 258 ? 11.990  6.581   8.281   1.00 27.25  ? 258 ILE C O   1 
ATOM   9226  C CB  . ILE C 1 258 ? 12.850  6.711   11.382  1.00 25.98  ? 258 ILE C CB  1 
ATOM   9227  C CG1 . ILE C 1 258 ? 14.090  6.100   10.717  1.00 26.06  ? 258 ILE C CG1 1 
ATOM   9228  C CG2 . ILE C 1 258 ? 12.005  5.595   11.985  1.00 25.86  ? 258 ILE C CG2 1 
ATOM   9229  C CD1 . ILE C 1 258 ? 15.111  7.057   10.216  1.00 30.39  ? 258 ILE C CD1 1 
ATOM   9230  N N   . TYR C 1 259 ? 10.058  6.492   9.421   1.00 24.28  ? 259 TYR C N   1 
ATOM   9231  C CA  . TYR C 1 259 ? 9.376   5.747   8.382   1.00 24.77  ? 259 TYR C CA  1 
ATOM   9232  C C   . TYR C 1 259 ? 9.176   6.651   7.166   1.00 23.82  ? 259 TYR C C   1 
ATOM   9233  O O   . TYR C 1 259 ? 9.230   6.208   6.007   1.00 27.83  ? 259 TYR C O   1 
ATOM   9234  C CB  . TYR C 1 259 ? 8.042   5.202   8.910   1.00 22.39  ? 259 TYR C CB  1 
ATOM   9235  C CG  . TYR C 1 259 ? 8.202   4.228   10.038  1.00 21.94  ? 259 TYR C CG  1 
ATOM   9236  C CD1 . TYR C 1 259 ? 8.472   2.888   9.805   1.00 23.91  ? 259 TYR C CD1 1 
ATOM   9237  C CD2 . TYR C 1 259 ? 8.133   4.655   11.356  1.00 23.63  ? 259 TYR C CD2 1 
ATOM   9238  C CE1 . TYR C 1 259 ? 8.567   1.973   10.847  1.00 26.40  ? 259 TYR C CE1 1 
ATOM   9239  C CE2 . TYR C 1 259 ? 8.308   3.768   12.403  1.00 23.47  ? 259 TYR C CE2 1 
ATOM   9240  C CZ  . TYR C 1 259 ? 8.559   2.433   12.157  1.00 27.73  ? 259 TYR C CZ  1 
ATOM   9241  O OH  . TYR C 1 259 ? 8.717   1.529   13.198  1.00 28.23  ? 259 TYR C OH  1 
ATOM   9242  N N   . ARG C 1 260 ? 8.826   7.899   7.449   1.00 20.97  ? 260 ARG C N   1 
ATOM   9243  C CA  . ARG C 1 260 ? 8.685   8.884   6.414   1.00 21.64  ? 260 ARG C CA  1 
ATOM   9244  C C   . ARG C 1 260 ? 10.027  9.285   5.815   1.00 22.35  ? 260 ARG C C   1 
ATOM   9245  O O   . ARG C 1 260 ? 10.110  9.458   4.591   1.00 22.26  ? 260 ARG C O   1 
ATOM   9246  C CB  . ARG C 1 260 ? 7.907   10.113  6.876   1.00 22.95  ? 260 ARG C CB  1 
ATOM   9247  C CG  . ARG C 1 260 ? 6.418   9.852   6.998   1.00 26.64  ? 260 ARG C CG  1 
ATOM   9248  C CD  . ARG C 1 260 ? 5.736   11.017  7.689   1.00 27.83  ? 260 ARG C CD  1 
ATOM   9249  N NE  . ARG C 1 260 ? 4.301   10.911  7.593   1.00 28.69  ? 260 ARG C NE  1 
ATOM   9250  C CZ  . ARG C 1 260 ? 3.428   11.517  8.380   1.00 30.57  ? 260 ARG C CZ  1 
ATOM   9251  N NH1 . ARG C 1 260 ? 3.842   12.158  9.457   1.00 30.68  ? 260 ARG C NH1 1 
ATOM   9252  N NH2 . ARG C 1 260 ? 2.130   11.413  8.120   1.00 27.59  ? 260 ARG C NH2 1 
ATOM   9253  N N   . SER C 1 261 ? 11.044  9.511   6.649   1.00 23.02  ? 261 SER C N   1 
ATOM   9254  C CA  . SER C 1 261 ? 12.303  10.003  6.120   1.00 23.55  ? 261 SER C CA  1 
ATOM   9255  C C   . SER C 1 261 ? 13.036  8.899   5.355   1.00 23.51  ? 261 SER C C   1 
ATOM   9256  O O   . SER C 1 261 ? 13.648  9.132   4.315   1.00 24.40  ? 261 SER C O   1 
ATOM   9257  C CB  . SER C 1 261 ? 13.183  10.641  7.205   1.00 23.36  ? 261 SER C CB  1 
ATOM   9258  O OG  . SER C 1 261 ? 13.691  9.673   8.115   1.00 23.52  ? 261 SER C OG  1 
ATOM   9259  N N   . PHE C 1 262 ? 13.010  7.686   5.878   1.00 23.57  ? 262 PHE C N   1 
ATOM   9260  C CA  . PHE C 1 262 ? 13.729  6.603   5.241   1.00 24.71  ? 262 PHE C CA  1 
ATOM   9261  C C   . PHE C 1 262 ? 13.017  6.081   3.989   1.00 26.70  ? 262 PHE C C   1 
ATOM   9262  O O   . PHE C 1 262 ? 13.682  5.686   3.026   1.00 25.52  ? 262 PHE C O   1 
ATOM   9263  C CB  . PHE C 1 262 ? 13.967  5.469   6.233   1.00 24.90  ? 262 PHE C CB  1 
ATOM   9264  C CG  . PHE C 1 262 ? 14.896  4.461   5.640   1.00 26.80  ? 262 PHE C CG  1 
ATOM   9265  C CD1 . PHE C 1 262 ? 16.229  4.803   5.377   1.00 26.68  ? 262 PHE C CD1 1 
ATOM   9266  C CD2 . PHE C 1 262 ? 14.454  3.190   5.329   1.00 25.71  ? 262 PHE C CD2 1 
ATOM   9267  C CE1 . PHE C 1 262 ? 17.081  3.877   4.783   1.00 26.89  ? 262 PHE C CE1 1 
ATOM   9268  C CE2 . PHE C 1 262 ? 15.320  2.268   4.741   1.00 27.50  ? 262 PHE C CE2 1 
ATOM   9269  C CZ  . PHE C 1 262 ? 16.618  2.623   4.458   1.00 23.61  ? 262 PHE C CZ  1 
ATOM   9270  N N   . SER C 1 263 ? 11.684  6.043   3.985   1.00 25.28  ? 263 SER C N   1 
ATOM   9271  C CA  . SER C 1 263 ? 10.982  5.711   2.755   1.00 26.76  ? 263 SER C CA  1 
ATOM   9272  C C   . SER C 1 263 ? 11.254  6.755   1.665   1.00 27.41  ? 263 SER C C   1 
ATOM   9273  O O   . SER C 1 263 ? 11.456  6.407   0.502   1.00 25.77  ? 263 SER C O   1 
ATOM   9274  C CB  . SER C 1 263 ? 9.508   5.437   2.960   1.00 25.34  ? 263 SER C CB  1 
ATOM   9275  O OG  . SER C 1 263 ? 8.779   6.574   3.402   1.00 25.33  ? 263 SER C OG  1 
ATOM   9276  N N   . ALA C 1 264 ? 11.293  8.035   2.015   1.00 24.87  ? 264 ALA C N   1 
ATOM   9277  C CA  . ALA C 1 264 ? 11.715  9.058   1.061   1.00 23.34  ? 264 ALA C CA  1 
ATOM   9278  C C   . ALA C 1 264 ? 13.124  8.772   0.538   1.00 24.10  ? 264 ALA C C   1 
ATOM   9279  O O   . ALA C 1 264 ? 13.391  8.863   -0.655  1.00 26.74  ? 264 ALA C O   1 
ATOM   9280  C CB  . ALA C 1 264 ? 11.648  10.440  1.693   1.00 24.85  ? 264 ALA C CB  1 
ATOM   9281  N N   . ALA C 1 265 ? 14.039  8.479   1.445   1.00 23.93  ? 265 ALA C N   1 
ATOM   9282  C CA  . ALA C 1 265 ? 15.393  8.136   1.080   1.00 25.65  ? 265 ALA C CA  1 
ATOM   9283  C C   . ALA C 1 265 ? 15.421  6.984   0.077   1.00 25.57  ? 265 ALA C C   1 
ATOM   9284  O O   . ALA C 1 265 ? 16.230  7.044   -0.821  1.00 22.96  ? 265 ALA C O   1 
ATOM   9285  C CB  . ALA C 1 265 ? 16.195  7.790   2.291   1.00 25.09  ? 265 ALA C CB  1 
ATOM   9286  N N   . MET C 1 266 ? 14.562  5.964   0.241   1.00 24.62  ? 266 MET C N   1 
ATOM   9287  C CA  . MET C 1 266 ? 14.538  4.815   -0.640  1.00 24.61  ? 266 MET C CA  1 
ATOM   9288  C C   . MET C 1 266 ? 14.019  5.197   -2.016  1.00 23.75  ? 266 MET C C   1 
ATOM   9289  O O   . MET C 1 266 ? 14.474  4.648   -3.019  1.00 26.92  ? 266 MET C O   1 
ATOM   9290  C CB  . MET C 1 266 ? 13.739  3.648   -0.048  1.00 25.14  ? 266 MET C CB  1 
ATOM   9291  C CG  . MET C 1 266 ? 14.420  3.058   1.150   1.00 23.91  ? 266 MET C CG  1 
ATOM   9292  S SD  . MET C 1 266 ? 16.082  2.396   0.845   1.00 27.94  ? 266 MET C SD  1 
ATOM   9293  C CE  . MET C 1 266 ? 17.112  3.828   1.174   1.00 29.31  ? 266 MET C CE  1 
ATOM   9294  N N   . ASN C 1 267 ? 13.138  6.192   -2.099  1.00 24.01  ? 267 ASN C N   1 
ATOM   9295  C CA  . ASN C 1 267 ? 12.722  6.697   -3.397  1.00 24.65  ? 267 ASN C CA  1 
ATOM   9296  C C   . ASN C 1 267 ? 13.901  7.329   -4.154  1.00 26.65  ? 267 ASN C C   1 
ATOM   9297  O O   . ASN C 1 267 ? 13.878  7.403   -5.393  1.00 23.78  ? 267 ASN C O   1 
ATOM   9298  C CB  . ASN C 1 267 ? 11.577  7.691   -3.231  1.00 26.31  ? 267 ASN C CB  1 
ATOM   9299  C CG  . ASN C 1 267 ? 10.247  7.026   -2.907  1.00 27.94  ? 267 ASN C CG  1 
ATOM   9300  O OD1 . ASN C 1 267 ? 10.152  5.815   -2.836  1.00 27.74  ? 267 ASN C OD1 1 
ATOM   9301  N ND2 . ASN C 1 267 ? 9.195   7.809   -2.742  1.00 29.52  ? 267 ASN C ND2 1 
ATOM   9302  N N   . GLY C 1 268 ? 14.873  7.874   -3.409  1.00 25.39  ? 268 GLY C N   1 
ATOM   9303  C CA  . GLY C 1 268 ? 16.042  8.500   -4.001  1.00 26.82  ? 268 GLY C CA  1 
ATOM   9304  C C   . GLY C 1 268 ? 17.059  7.446   -4.411  1.00 25.03  ? 268 GLY C C   1 
ATOM   9305  O O   . GLY C 1 268 ? 17.618  7.509   -5.500  1.00 26.88  ? 268 GLY C O   1 
ATOM   9306  N N   . LEU C 1 269 ? 17.228  6.445   -3.553  1.00 26.52  ? 269 LEU C N   1 
ATOM   9307  C CA  . LEU C 1 269 ? 18.122  5.335   -3.830  1.00 27.49  ? 269 LEU C CA  1 
ATOM   9308  C C   . LEU C 1 269 ? 17.647  4.556   -5.047  1.00 30.51  ? 269 LEU C C   1 
ATOM   9309  O O   . LEU C 1 269 ? 18.492  4.011   -5.736  1.00 27.89  ? 269 LEU C O   1 
ATOM   9310  C CB  . LEU C 1 269 ? 18.249  4.418   -2.619  1.00 30.01  ? 269 LEU C CB  1 
ATOM   9311  C CG  . LEU C 1 269 ? 19.307  3.330   -2.758  1.00 32.96  ? 269 LEU C CG  1 
ATOM   9312  C CD1 . LEU C 1 269 ? 20.711  3.928   -2.871  1.00 35.09  ? 269 LEU C CD1 1 
ATOM   9313  C CD2 . LEU C 1 269 ? 19.254  2.386   -1.593  1.00 29.14  ? 269 LEU C CD2 1 
ATOM   9314  N N   . ALA C 1 270 ? 16.334  4.544   -5.316  1.00 26.88  ? 270 ALA C N   1 
ATOM   9315  C CA  . ALA C 1 270 ? 15.753  3.824   -6.435  1.00 28.90  ? 270 ALA C CA  1 
ATOM   9316  C C   . ALA C 1 270 ? 16.137  4.472   -7.765  1.00 31.47  ? 270 ALA C C   1 
ATOM   9317  O O   . ALA C 1 270 ? 15.914  3.879   -8.798  1.00 28.25  ? 270 ALA C O   1 
ATOM   9318  C CB  . ALA C 1 270 ? 14.240  3.777   -6.334  1.00 27.12  ? 270 ALA C CB  1 
ATOM   9319  N N   . GLY C 1 271 ? 16.579  5.732   -7.742  1.00 29.41  ? 271 GLY C N   1 
ATOM   9320  C CA  . GLY C 1 271 ? 16.916  6.440   -8.962  1.00 30.72  ? 271 GLY C CA  1 
ATOM   9321  C C   . GLY C 1 271 ? 18.090  5.772   -9.681  1.00 28.03  ? 271 GLY C C   1 
ATOM   9322  O O   . GLY C 1 271 ? 19.070  5.386   -9.055  1.00 25.11  ? 271 GLY C O   1 
ATOM   9323  N N   . PRO C 1 272 ? 18.066  5.686   -11.022 1.00 28.37  ? 272 PRO C N   1 
ATOM   9324  C CA  . PRO C 1 272 ? 19.194  5.153   -11.790 1.00 30.85  ? 272 PRO C CA  1 
ATOM   9325  C C   . PRO C 1 272 ? 20.593  5.707   -11.503 1.00 31.21  ? 272 PRO C C   1 
ATOM   9326  O O   . PRO C 1 272 ? 21.554  4.966   -11.605 1.00 35.82  ? 272 PRO C O   1 
ATOM   9327  C CB  . PRO C 1 272 ? 18.799  5.517   -13.219 1.00 33.46  ? 272 PRO C CB  1 
ATOM   9328  C CG  . PRO C 1 272 ? 17.321  5.451   -13.212 1.00 32.24  ? 272 PRO C CG  1 
ATOM   9329  C CD  . PRO C 1 272 ? 16.925  6.042   -11.875 1.00 33.32  ? 272 PRO C CD  1 
ATOM   9330  N N   . LEU C 1 273 ? 20.727  6.953   -11.032 1.00 31.96  ? 273 LEU C N   1 
ATOM   9331  C CA  . LEU C 1 273 ? 22.047  7.557   -10.830 1.00 31.48  ? 273 LEU C CA  1 
ATOM   9332  C C   . LEU C 1 273 ? 22.531  7.350   -9.410  1.00 33.46  ? 273 LEU C C   1 
ATOM   9333  O O   . LEU C 1 273 ? 23.627  7.780   -9.051  1.00 36.08  ? 273 LEU C O   1 
ATOM   9334  C CB  . LEU C 1 273 ? 21.984  9.061   -11.102 1.00 35.47  ? 273 LEU C CB  1 
ATOM   9335  C CG  . LEU C 1 273 ? 21.628  9.450   -12.518 1.00 34.08  ? 273 LEU C CG  1 
ATOM   9336  C CD1 . LEU C 1 273 ? 21.725  10.959  -12.711 1.00 38.31  ? 273 LEU C CD1 1 
ATOM   9337  C CD2 . LEU C 1 273 ? 22.568  8.739   -13.479 1.00 40.44  ? 273 LEU C CD2 1 
ATOM   9338  N N   . HIS C 1 274 ? 21.762  6.650   -8.592  1.00 31.14  ? 274 HIS C N   1 
ATOM   9339  C CA  . HIS C 1 274 ? 22.224  6.435   -7.240  1.00 32.66  ? 274 HIS C CA  1 
ATOM   9340  C C   . HIS C 1 274 ? 22.267  4.959   -6.912  1.00 34.93  ? 274 HIS C C   1 
ATOM   9341  O O   . HIS C 1 274 ? 23.146  4.609   -6.149  1.00 37.44  ? 274 HIS C O   1 
ATOM   9342  C CB  . HIS C 1 274 ? 21.362  7.210   -6.222  1.00 35.78  ? 274 HIS C CB  1 
ATOM   9343  C CG  . HIS C 1 274 ? 21.824  7.165   -4.802  1.00 34.42  ? 274 HIS C CG  1 
ATOM   9344  N ND1 . HIS C 1 274 ? 23.110  6.903   -4.399  1.00 37.13  ? 274 HIS C ND1 1 
ATOM   9345  C CD2 . HIS C 1 274 ? 21.139  7.430   -3.652  1.00 37.91  ? 274 HIS C CD2 1 
ATOM   9346  C CE1 . HIS C 1 274 ? 23.188  6.948   -3.071  1.00 41.58  ? 274 HIS C CE1 1 
ATOM   9347  N NE2 . HIS C 1 274 ? 22.005  7.278   -2.586  1.00 37.72  ? 274 HIS C NE2 1 
ATOM   9348  N N   . GLY C 1 275 ? 21.295  4.151   -7.387  1.00 35.96  ? 275 GLY C N   1 
ATOM   9349  C CA  . GLY C 1 275 ? 21.154  2.794   -6.880  1.00 36.92  ? 275 GLY C CA  1 
ATOM   9350  C C   . GLY C 1 275 ? 21.306  1.648   -7.897  1.00 35.53  ? 275 GLY C C   1 
ATOM   9351  O O   . GLY C 1 275 ? 21.095  0.503   -7.521  1.00 37.89  ? 275 GLY C O   1 
ATOM   9352  N N   . LEU C 1 276 ? 21.700  1.925   -9.142  1.00 31.04  ? 276 LEU C N   1 
ATOM   9353  C CA  . LEU C 1 276 ? 21.639  0.929   -10.201 1.00 35.03  ? 276 LEU C CA  1 
ATOM   9354  C C   . LEU C 1 276 ? 23.035  0.391   -10.599 1.00 35.57  ? 276 LEU C C   1 
ATOM   9355  O O   . LEU C 1 276 ? 23.150  -0.592  -11.350 1.00 30.94  ? 276 LEU C O   1 
ATOM   9356  C CB  . LEU C 1 276 ? 20.917  1.621   -11.358 1.00 40.49  ? 276 LEU C CB  1 
ATOM   9357  C CG  . LEU C 1 276 ? 19.928  0.808   -12.190 1.00 56.80  ? 276 LEU C CG  1 
ATOM   9358  C CD1 . LEU C 1 276 ? 19.383  1.644   -13.347 1.00 54.83  ? 276 LEU C CD1 1 
ATOM   9359  C CD2 . LEU C 1 276 ? 20.565  -0.448  -12.750 1.00 65.90  ? 276 LEU C CD2 1 
ATOM   9360  N N   . ALA C 1 277 ? 24.128  0.960   -10.057 1.00 31.90  ? 277 ALA C N   1 
ATOM   9361  C CA  . ALA C 1 277 ? 25.471  0.733   -10.611 1.00 34.58  ? 277 ALA C CA  1 
ATOM   9362  C C   . ALA C 1 277 ? 25.954  -0.718  -10.444 1.00 34.63  ? 277 ALA C C   1 
ATOM   9363  O O   . ALA C 1 277 ? 26.628  -1.277  -11.304 1.00 30.82  ? 277 ALA C O   1 
ATOM   9364  C CB  . ALA C 1 277 ? 26.450  1.712   -9.994  1.00 34.43  ? 277 ALA C CB  1 
ATOM   9365  N N   . ASN C 1 278 ? 25.591  -1.363  -9.349  1.00 29.55  ? 278 ASN C N   1 
ATOM   9366  C CA  . ASN C 1 278 ? 25.900  -2.770  -9.101  1.00 31.41  ? 278 ASN C CA  1 
ATOM   9367  C C   . ASN C 1 278 ? 25.413  -3.639  -10.272 1.00 29.31  ? 278 ASN C C   1 
ATOM   9368  O O   . ASN C 1 278 ? 26.182  -4.420  -10.811 1.00 30.52  ? 278 ASN C O   1 
ATOM   9369  C CB  . ASN C 1 278 ? 25.285  -3.195  -7.746  1.00 31.25  ? 278 ASN C CB  1 
ATOM   9370  C CG  . ASN C 1 278 ? 25.367  -4.670  -7.438  1.00 36.60  ? 278 ASN C CG  1 
ATOM   9371  O OD1 . ASN C 1 278 ? 25.676  -5.489  -8.302  1.00 39.37  ? 278 ASN C OD1 1 
ATOM   9372  N ND2 . ASN C 1 278 ? 25.057  -5.042  -6.213  1.00 32.57  ? 278 ASN C ND2 1 
ATOM   9373  N N   A GLN C 1 279 ? 24.120  -3.528  -10.601 0.25 30.08  ? 279 GLN C N   1 
ATOM   9374  N N   B GLN C 1 279 ? 24.104  -3.522  -10.592 0.25 28.03  ? 279 GLN C N   1 
ATOM   9375  N N   C GLN C 1 279 ? 24.149  -3.490  -10.645 0.50 32.39  ? 279 GLN C N   1 
ATOM   9376  C CA  A GLN C 1 279 ? 23.503  -4.249  -11.705 0.25 29.31  ? 279 GLN C CA  1 
ATOM   9377  C CA  B GLN C 1 279 ? 23.423  -4.206  -11.694 0.25 25.83  ? 279 GLN C CA  1 
ATOM   9378  C CA  C GLN C 1 279 ? 23.529  -4.285  -11.689 0.50 32.09  ? 279 GLN C CA  1 
ATOM   9379  C C   A GLN C 1 279 ? 24.251  -3.970  -13.004 0.25 30.44  ? 279 GLN C C   1 
ATOM   9380  C C   B GLN C 1 279 ? 24.162  -3.956  -13.012 0.25 28.67  ? 279 GLN C C   1 
ATOM   9381  C C   C GLN C 1 279 ? 24.110  -3.953  -13.068 0.50 32.71  ? 279 GLN C C   1 
ATOM   9382  O O   A GLN C 1 279 ? 24.627  -4.893  -13.722 0.25 29.11  ? 279 GLN C O   1 
ATOM   9383  O O   B GLN C 1 279 ? 24.457  -4.893  -13.750 0.25 28.10  ? 279 GLN C O   1 
ATOM   9384  O O   C GLN C 1 279 ? 24.215  -4.830  -13.923 0.50 32.23  ? 279 GLN C O   1 
ATOM   9385  C CB  A GLN C 1 279 ? 22.055  -3.787  -11.884 0.25 29.77  ? 279 GLN C CB  1 
ATOM   9386  C CB  B GLN C 1 279 ? 21.944  -3.767  -11.814 0.25 23.54  ? 279 GLN C CB  1 
ATOM   9387  C CB  C GLN C 1 279 ? 22.030  -4.025  -11.567 0.50 36.13  ? 279 GLN C CB  1 
ATOM   9388  C CG  A GLN C 1 279 ? 21.457  -3.245  -10.602 0.25 28.09  ? 279 GLN C CG  1 
ATOM   9389  C CG  B GLN C 1 279 ? 21.339  -3.960  -13.212 0.25 19.59  ? 279 GLN C CG  1 
ATOM   9390  C CG  C GLN C 1 279 ? 21.560  -4.293  -10.146 0.50 34.66  ? 279 GLN C CG  1 
ATOM   9391  C CD  A GLN C 1 279 ? 19.955  -3.209  -10.640 0.25 25.81  ? 279 GLN C CD  1 
ATOM   9392  C CD  B GLN C 1 279 ? 19.836  -4.083  -13.365 0.25 17.66  ? 279 GLN C CD  1 
ATOM   9393  C CD  C GLN C 1 279 ? 21.176  -3.104  -9.291  0.50 30.64  ? 279 GLN C CD  1 
ATOM   9394  O OE1 A GLN C 1 279 ? 19.332  -3.471  -11.666 0.25 28.08  ? 279 GLN C OE1 1 
ATOM   9395  O OE1 B GLN C 1 279 ? 19.356  -4.547  -14.391 0.25 14.45  ? 279 GLN C OE1 1 
ATOM   9396  O OE1 C GLN C 1 279 ? 22.016  -2.427  -8.674  0.50 25.15  ? 279 GLN C OE1 1 
ATOM   9397  N NE2 A GLN C 1 279 ? 19.370  -2.912  -9.493  0.25 23.81  ? 279 GLN C NE2 1 
ATOM   9398  N NE2 B GLN C 1 279 ? 19.061  -3.722  -12.355 0.25 17.88  ? 279 GLN C NE2 1 
ATOM   9399  N NE2 C GLN C 1 279 ? 19.863  -2.917  -9.184  0.50 24.61  ? 279 GLN C NE2 1 
ATOM   9400  N N   . GLU C 1 280 ? 24.448  -2.682  -13.297 1.00 31.26  ? 280 GLU C N   1 
ATOM   9401  C CA  . GLU C 1 280 ? 25.087  -2.261  -14.537 1.00 36.38  ? 280 GLU C CA  1 
ATOM   9402  C C   . GLU C 1 280 ? 26.457  -2.919  -14.634 1.00 35.55  ? 280 GLU C C   1 
ATOM   9403  O O   . GLU C 1 280 ? 26.780  -3.454  -15.679 1.00 29.66  ? 280 GLU C O   1 
ATOM   9404  C CB  . GLU C 1 280 ? 25.202  -0.736  -14.629 1.00 42.68  ? 280 GLU C CB  1 
ATOM   9405  C CG  . GLU C 1 280 ? 23.884  -0.074  -15.033 1.00 50.86  ? 280 GLU C CG  1 
ATOM   9406  C CD  . GLU C 1 280 ? 23.686  1.405   -14.696 1.00 60.04  ? 280 GLU C CD  1 
ATOM   9407  O OE1 . GLU C 1 280 ? 22.592  1.931   -15.028 1.00 66.38  ? 280 GLU C OE1 1 
ATOM   9408  O OE2 . GLU C 1 280 ? 24.599  2.030   -14.083 1.00 61.33  ? 280 GLU C OE2 1 
ATOM   9409  N N   . VAL C 1 281 ? 27.202  -2.976  -13.523 1.00 29.06  ? 281 VAL C N   1 
ATOM   9410  C CA  . VAL C 1 281 ? 28.510  -3.593  -13.567 1.00 28.85  ? 281 VAL C CA  1 
ATOM   9411  C C   . VAL C 1 281 ? 28.379  -5.070  -13.924 1.00 31.27  ? 281 VAL C C   1 
ATOM   9412  O O   . VAL C 1 281 ? 29.040  -5.546  -14.848 1.00 29.51  ? 281 VAL C O   1 
ATOM   9413  C CB  . VAL C 1 281 ? 29.292  -3.330  -12.272 1.00 28.11  ? 281 VAL C CB  1 
ATOM   9414  C CG1 . VAL C 1 281 ? 30.507  -4.238  -12.156 1.00 29.52  ? 281 VAL C CG1 1 
ATOM   9415  C CG2 . VAL C 1 281 ? 29.724  -1.867  -12.207 1.00 30.58  ? 281 VAL C CG2 1 
ATOM   9416  N N   . LEU C 1 282 ? 27.514  -5.795  -13.201 1.00 29.22  ? 282 LEU C N   1 
ATOM   9417  C CA  . LEU C 1 282 ? 27.358  -7.222  -13.390 1.00 29.59  ? 282 LEU C CA  1 
ATOM   9418  C C   . LEU C 1 282 ? 26.971  -7.561  -14.826 1.00 31.08  ? 282 LEU C C   1 
ATOM   9419  O O   . LEU C 1 282 ? 27.481  -8.528  -15.407 1.00 29.42  ? 282 LEU C O   1 
ATOM   9420  C CB  . LEU C 1 282 ? 26.308  -7.785  -12.421 1.00 29.68  ? 282 LEU C CB  1 
ATOM   9421  C CG  . LEU C 1 282 ? 26.067  -9.284  -12.555 1.00 27.52  ? 282 LEU C CG  1 
ATOM   9422  C CD1 . LEU C 1 282 ? 27.386  -10.040 -12.481 1.00 28.40  ? 282 LEU C CD1 1 
ATOM   9423  C CD2 . LEU C 1 282 ? 25.106  -9.802  -11.473 1.00 28.26  ? 282 LEU C CD2 1 
ATOM   9424  N N   . ARG C 1 283 ? 26.036  -6.798  -15.387 1.00 29.29  ? 283 ARG C N   1 
ATOM   9425  C CA  . ARG C 1 283 ? 25.605  -7.066  -16.746 1.00 31.67  ? 283 ARG C CA  1 
ATOM   9426  C C   . ARG C 1 283 ? 26.755  -6.798  -17.716 1.00 34.56  ? 283 ARG C C   1 
ATOM   9427  O O   . ARG C 1 283 ? 26.921  -7.515  -18.683 1.00 32.12  ? 283 ARG C O   1 
ATOM   9428  C CB  . ARG C 1 283 ? 24.373  -6.237  -17.115 1.00 36.29  ? 283 ARG C CB  1 
ATOM   9429  C CG  . ARG C 1 283 ? 23.074  -6.663  -16.438 1.00 36.01  ? 283 ARG C CG  1 
ATOM   9430  C CD  . ARG C 1 283 ? 21.972  -5.742  -16.943 1.00 40.60  ? 283 ARG C CD  1 
ATOM   9431  N NE  . ARG C 1 283 ? 20.664  -5.928  -16.332 1.00 40.40  ? 283 ARG C NE  1 
ATOM   9432  C CZ  . ARG C 1 283 ? 19.869  -6.966  -16.552 1.00 48.36  ? 283 ARG C CZ  1 
ATOM   9433  N NH1 . ARG C 1 283 ? 20.226  -7.925  -17.381 1.00 46.20  ? 283 ARG C NH1 1 
ATOM   9434  N NH2 . ARG C 1 283 ? 18.698  -7.038  -15.945 1.00 49.75  ? 283 ARG C NH2 1 
ATOM   9435  N N   . TRP C 1 284 ? 27.568  -5.776  -17.468 1.00 30.29  ? 284 TRP C N   1 
ATOM   9436  C CA  . TRP C 1 284 ? 28.719  -5.520  -18.330 1.00 33.82  ? 284 TRP C CA  1 
ATOM   9437  C C   . TRP C 1 284 ? 29.749  -6.654  -18.235 1.00 32.45  ? 284 TRP C C   1 
ATOM   9438  O O   . TRP C 1 284 ? 30.299  -7.085  -19.257 1.00 31.27  ? 284 TRP C O   1 
ATOM   9439  C CB  . TRP C 1 284 ? 29.314  -4.162  -17.949 1.00 34.50  ? 284 TRP C CB  1 
ATOM   9440  C CG  . TRP C 1 284 ? 30.381  -3.595  -18.832 1.00 34.55  ? 284 TRP C CG  1 
ATOM   9441  C CD1 . TRP C 1 284 ? 30.238  -2.898  -20.000 1.00 34.79  ? 284 TRP C CD1 1 
ATOM   9442  C CD2 . TRP C 1 284 ? 31.781  -3.583  -18.529 1.00 33.79  ? 284 TRP C CD2 1 
ATOM   9443  N NE1 . TRP C 1 284 ? 31.461  -2.461  -20.436 1.00 35.29  ? 284 TRP C NE1 1 
ATOM   9444  C CE2 . TRP C 1 284 ? 32.426  -2.875  -19.564 1.00 37.86  ? 284 TRP C CE2 1 
ATOM   9445  C CE3 . TRP C 1 284 ? 32.547  -4.098  -17.486 1.00 34.69  ? 284 TRP C CE3 1 
ATOM   9446  C CZ2 . TRP C 1 284 ? 33.807  -2.696  -19.594 1.00 38.82  ? 284 TRP C CZ2 1 
ATOM   9447  C CZ3 . TRP C 1 284 ? 33.912  -3.914  -17.513 1.00 36.99  ? 284 TRP C CZ3 1 
ATOM   9448  C CH2 . TRP C 1 284 ? 34.529  -3.222  -18.549 1.00 33.80  ? 284 TRP C CH2 1 
ATOM   9449  N N   . ILE C 1 285 ? 30.006  -7.154  -17.017 1.00 30.53  ? 285 ILE C N   1 
ATOM   9450  C CA  . ILE C 1 285 ? 30.926  -8.273  -16.825 1.00 31.97  ? 285 ILE C CA  1 
ATOM   9451  C C   . ILE C 1 285 ? 30.426  -9.513  -17.580 1.00 34.42  ? 285 ILE C C   1 
ATOM   9452  O O   . ILE C 1 285 ? 31.231  -10.234 -18.192 1.00 30.26  ? 285 ILE C O   1 
ATOM   9453  C CB  . ILE C 1 285 ? 31.168  -8.554  -15.332 1.00 31.11  ? 285 ILE C CB  1 
ATOM   9454  C CG1 . ILE C 1 285 ? 31.876  -7.388  -14.629 1.00 31.67  ? 285 ILE C CG1 1 
ATOM   9455  C CG2 . ILE C 1 285 ? 31.885  -9.869  -15.140 1.00 33.47  ? 285 ILE C CG2 1 
ATOM   9456  C CD1 . ILE C 1 285 ? 33.295  -7.144  -15.047 1.00 33.72  ? 285 ILE C CD1 1 
ATOM   9457  N N   . GLN C 1 286 ? 29.100  -9.736  -17.546 1.00 32.40  ? 286 GLN C N   1 
ATOM   9458  C CA  . GLN C 1 286 ? 28.476  -10.870 -18.202 1.00 33.04  ? 286 GLN C CA  1 
ATOM   9459  C C   . GLN C 1 286 ? 28.529  -10.680 -19.719 1.00 31.17  ? 286 GLN C C   1 
ATOM   9460  O O   . GLN C 1 286 ? 28.735  -11.638 -20.453 1.00 30.15  ? 286 GLN C O   1 
ATOM   9461  C CB  . GLN C 1 286 ? 27.049  -11.090 -17.697 1.00 31.40  ? 286 GLN C CB  1 
ATOM   9462  C CG  . GLN C 1 286 ? 26.979  -11.572 -16.243 1.00 32.60  ? 286 GLN C CG  1 
ATOM   9463  C CD  . GLN C 1 286 ? 25.580  -11.511 -15.692 1.00 32.44  ? 286 GLN C CD  1 
ATOM   9464  O OE1 . GLN C 1 286 ? 24.886  -10.519 -15.872 1.00 34.88  ? 286 GLN C OE1 1 
ATOM   9465  N NE2 . GLN C 1 286 ? 25.131  -12.591 -15.068 1.00 35.27  ? 286 GLN C NE2 1 
ATOM   9466  N N   . MET C 1 287 ? 28.331  -9.451  -20.183 1.00 31.28  ? 287 MET C N   1 
ATOM   9467  C CA  . MET C 1 287 ? 28.499  -9.136  -21.596 1.00 34.30  ? 287 MET C CA  1 
ATOM   9468  C C   . MET C 1 287 ? 29.939  -9.453  -22.034 1.00 38.42  ? 287 MET C C   1 
ATOM   9469  O O   . MET C 1 287 ? 30.100  -10.071 -23.081 1.00 38.00  ? 287 MET C O   1 
ATOM   9470  C CB  . MET C 1 287 ? 28.119  -7.684  -21.914 1.00 34.33  ? 287 MET C CB  1 
ATOM   9471  C CG  . MET C 1 287 ? 28.465  -7.220  -23.343 1.00 36.25  ? 287 MET C CG  1 
ATOM   9472  S SD  . MET C 1 287 ? 30.180  -6.622  -23.525 1.00 41.01  ? 287 MET C SD  1 
ATOM   9473  C CE  . MET C 1 287 ? 30.194  -5.155  -22.484 1.00 43.97  ? 287 MET C CE  1 
ATOM   9474  N N   . LEU C 1 288 ? 30.977  -9.136  -21.230 1.00 36.11  ? 288 LEU C N   1 
ATOM   9475  C CA  . LEU C 1 288 ? 32.362  -9.449  -21.609 1.00 35.42  ? 288 LEU C CA  1 
ATOM   9476  C C   . LEU C 1 288 ? 32.565  -10.961 -21.715 1.00 40.87  ? 288 LEU C C   1 
ATOM   9477  O O   . LEU C 1 288 ? 33.244  -11.461 -22.621 1.00 38.10  ? 288 LEU C O   1 
ATOM   9478  C CB  . LEU C 1 288 ? 33.382  -8.870  -20.622 1.00 33.14  ? 288 LEU C CB  1 
ATOM   9479  C CG  . LEU C 1 288 ? 33.554  -7.345  -20.645 1.00 36.55  ? 288 LEU C CG  1 
ATOM   9480  C CD1 . LEU C 1 288 ? 34.470  -6.897  -19.517 1.00 39.07  ? 288 LEU C CD1 1 
ATOM   9481  C CD2 . LEU C 1 288 ? 34.136  -6.844  -21.959 1.00 38.85  ? 288 LEU C CD2 1 
ATOM   9482  N N   . TYR C 1 289 ? 32.047  -11.699 -20.739 1.00 35.93  ? 289 TYR C N   1 
ATOM   9483  C CA  . TYR C 1 289 ? 32.266  -13.139 -20.697 1.00 36.31  ? 289 TYR C CA  1 
ATOM   9484  C C   . TYR C 1 289 ? 31.706  -13.767 -21.975 1.00 35.30  ? 289 TYR C C   1 
ATOM   9485  O O   . TYR C 1 289 ? 32.338  -14.617 -22.592 1.00 33.15  ? 289 TYR C O   1 
ATOM   9486  C CB  . TYR C 1 289 ? 31.632  -13.720 -19.437 1.00 36.15  ? 289 TYR C CB  1 
ATOM   9487  C CG  . TYR C 1 289 ? 31.794  -15.205 -19.274 1.00 42.27  ? 289 TYR C CG  1 
ATOM   9488  C CD1 . TYR C 1 289 ? 32.934  -15.744 -18.708 1.00 43.91  ? 289 TYR C CD1 1 
ATOM   9489  C CD2 . TYR C 1 289 ? 30.807  -16.071 -19.709 1.00 49.63  ? 289 TYR C CD2 1 
ATOM   9490  C CE1 . TYR C 1 289 ? 33.095  -17.112 -18.579 1.00 45.61  ? 289 TYR C CE1 1 
ATOM   9491  C CE2 . TYR C 1 289 ? 30.947  -17.443 -19.578 1.00 55.32  ? 289 TYR C CE2 1 
ATOM   9492  C CZ  . TYR C 1 289 ? 32.095  -17.958 -19.012 1.00 51.95  ? 289 TYR C CZ  1 
ATOM   9493  O OH  . TYR C 1 289 ? 32.240  -19.305 -18.890 1.00 67.23  ? 289 TYR C OH  1 
ATOM   9494  N N   . LYS C 1 290 ? 30.524  -13.308 -22.384 1.00 38.28  ? 290 LYS C N   1 
ATOM   9495  C CA  . LYS C 1 290 ? 29.847  -13.832 -23.553 1.00 44.74  ? 290 LYS C CA  1 
ATOM   9496  C C   . LYS C 1 290 ? 30.519  -13.367 -24.853 1.00 49.58  ? 290 LYS C C   1 
ATOM   9497  O O   . LYS C 1 290 ? 30.580  -14.127 -25.807 1.00 41.19  ? 290 LYS C O   1 
ATOM   9498  C CB  . LYS C 1 290 ? 28.387  -13.394 -23.560 1.00 41.56  ? 290 LYS C CB  1 
ATOM   9499  C CG  . LYS C 1 290 ? 27.587  -14.034 -24.675 1.00 47.45  ? 290 LYS C CG  1 
ATOM   9500  C CD  . LYS C 1 290 ? 26.203  -13.491 -24.833 1.00 56.03  ? 290 LYS C CD  1 
ATOM   9501  C CE  . LYS C 1 290 ? 25.402  -14.327 -25.808 1.00 56.20  ? 290 LYS C CE  1 
ATOM   9502  N NZ  . LYS C 1 290 ? 24.204  -13.588 -26.252 1.00 62.45  ? 290 LYS C NZ  1 
ATOM   9503  N N   . LYS C 1 291 ? 30.983  -12.111 -24.912 1.00 42.89  ? 291 LYS C N   1 
ATOM   9504  C CA  . LYS C 1 291 ? 31.607  -11.600 -26.121 1.00 42.93  ? 291 LYS C CA  1 
ATOM   9505  C C   . LYS C 1 291 ? 32.917  -12.340 -26.395 1.00 44.94  ? 291 LYS C C   1 
ATOM   9506  O O   . LYS C 1 291 ? 33.233  -12.567 -27.542 1.00 42.37  ? 291 LYS C O   1 
ATOM   9507  C CB  . LYS C 1 291 ? 31.827  -10.095 -26.021 1.00 39.50  ? 291 LYS C CB  1 
ATOM   9508  C CG  . LYS C 1 291 ? 32.724  -9.479  -27.089 1.00 44.50  ? 291 LYS C CG  1 
ATOM   9509  C CD  . LYS C 1 291 ? 32.732  -7.964  -26.997 1.00 49.53  ? 291 LYS C CD  1 
ATOM   9510  C CE  . LYS C 1 291 ? 33.594  -7.264  -28.033 1.00 57.90  ? 291 LYS C CE  1 
ATOM   9511  N NZ  . LYS C 1 291 ? 33.032  -7.388  -29.395 1.00 56.36  ? 291 LYS C NZ  1 
ATOM   9512  N N   . PHE C 1 292 ? 33.670  -12.729 -25.359 1.00 40.11  ? 292 PHE C N   1 
ATOM   9513  C CA  . PHE C 1 292 ? 34.991  -13.299 -25.565 1.00 44.92  ? 292 PHE C CA  1 
ATOM   9514  C C   . PHE C 1 292 ? 34.993  -14.810 -25.335 1.00 47.70  ? 292 PHE C C   1 
ATOM   9515  O O   . PHE C 1 292 ? 36.051  -15.427 -25.401 1.00 45.31  ? 292 PHE C O   1 
ATOM   9516  C CB  . PHE C 1 292 ? 36.001  -12.555 -24.684 1.00 43.56  ? 292 PHE C CB  1 
ATOM   9517  C CG  . PHE C 1 292 ? 36.259  -11.143 -25.156 1.00 44.18  ? 292 PHE C CG  1 
ATOM   9518  C CD1 . PHE C 1 292 ? 36.989  -10.918 -26.311 1.00 43.89  ? 292 PHE C CD1 1 
ATOM   9519  C CD2 . PHE C 1 292 ? 35.755  -10.048 -24.470 1.00 37.05  ? 292 PHE C CD2 1 
ATOM   9520  C CE1 . PHE C 1 292 ? 37.211  -9.631  -26.769 1.00 45.36  ? 292 PHE C CE1 1 
ATOM   9521  C CE2 . PHE C 1 292 ? 35.962  -8.762  -24.928 1.00 44.86  ? 292 PHE C CE2 1 
ATOM   9522  C CZ  . PHE C 1 292 ? 36.695  -8.550  -26.075 1.00 51.33  ? 292 PHE C CZ  1 
ATOM   9523  N N   . GLY C 1 293 ? 33.818  -15.395 -25.064 1.00 44.73  ? 293 GLY C N   1 
ATOM   9524  C CA  . GLY C 1 293 ? 33.689  -16.813 -24.764 1.00 43.24  ? 293 GLY C CA  1 
ATOM   9525  C C   . GLY C 1 293 ? 34.586  -17.245 -23.607 1.00 46.53  ? 293 GLY C C   1 
ATOM   9526  O O   . GLY C 1 293 ? 35.257  -18.253 -23.704 1.00 55.10  ? 293 GLY C O   1 
ATOM   9527  N N   . GLY C 1 294 ? 34.580  -16.507 -22.493 1.00 43.37  ? 294 GLY C N   1 
ATOM   9528  C CA  . GLY C 1 294 ? 35.520  -16.765 -21.414 1.00 42.55  ? 294 GLY C CA  1 
ATOM   9529  C C   . GLY C 1 294 ? 36.144  -15.469 -20.894 1.00 40.32  ? 294 GLY C C   1 
ATOM   9530  O O   . GLY C 1 294 ? 35.706  -14.373 -21.229 1.00 41.90  ? 294 GLY C O   1 
ATOM   9531  N N   . VAL C 1 295 ? 37.119  -15.607 -20.007 1.00 40.47  ? 295 VAL C N   1 
ATOM   9532  C CA  . VAL C 1 295 ? 37.857  -14.468 -19.508 1.00 40.73  ? 295 VAL C CA  1 
ATOM   9533  C C   . VAL C 1 295 ? 38.662  -13.893 -20.669 1.00 43.59  ? 295 VAL C C   1 
ATOM   9534  O O   . VAL C 1 295 ? 39.440  -14.606 -21.289 1.00 40.68  ? 295 VAL C O   1 
ATOM   9535  C CB  . VAL C 1 295 ? 38.763  -14.887 -18.340 1.00 45.41  ? 295 VAL C CB  1 
ATOM   9536  C CG1 . VAL C 1 295 ? 39.498  -13.698 -17.740 1.00 42.73  ? 295 VAL C CG1 1 
ATOM   9537  C CG2 . VAL C 1 295 ? 37.967  -15.642 -17.276 1.00 46.68  ? 295 VAL C CG2 1 
ATOM   9538  N N   . PRO C 1 296 ? 38.503  -12.604 -21.034 1.00 41.37  ? 296 PRO C N   1 
ATOM   9539  C CA  . PRO C 1 296 ? 39.407  -11.992 -22.011 1.00 39.08  ? 296 PRO C CA  1 
ATOM   9540  C C   . PRO C 1 296 ? 40.867  -11.905 -21.554 1.00 44.30  ? 296 PRO C C   1 
ATOM   9541  O O   . PRO C 1 296 ? 41.169  -11.887 -20.362 1.00 41.97  ? 296 PRO C O   1 
ATOM   9542  C CB  . PRO C 1 296 ? 38.786  -10.605 -22.278 1.00 38.50  ? 296 PRO C CB  1 
ATOM   9543  C CG  . PRO C 1 296 ? 37.874  -10.334 -21.089 1.00 43.56  ? 296 PRO C CG  1 
ATOM   9544  C CD  . PRO C 1 296 ? 37.426  -11.697 -20.600 1.00 39.52  ? 296 PRO C CD  1 
ATOM   9545  N N   . THR C 1 297 ? 41.793  -11.881 -22.526 1.00 37.47  ? 297 THR C N   1 
ATOM   9546  C CA  . THR C 1 297 ? 43.171  -11.498 -22.259 1.00 39.58  ? 297 THR C CA  1 
ATOM   9547  C C   . THR C 1 297 ? 43.251  -10.004 -21.919 1.00 36.31  ? 297 THR C C   1 
ATOM   9548  O O   . THR C 1 297 ? 42.319  -9.228  -22.167 1.00 39.05  ? 297 THR C O   1 
ATOM   9549  C CB  . THR C 1 297 ? 44.050  -11.785 -23.491 1.00 41.44  ? 297 THR C CB  1 
ATOM   9550  O OG1 . THR C 1 297 ? 43.540  -10.974 -24.545 1.00 41.36  ? 297 THR C OG1 1 
ATOM   9551  C CG2 . THR C 1 297 ? 44.012  -13.233 -23.929 1.00 41.41  ? 297 THR C CG2 1 
ATOM   9552  N N   . LYS C 1 298 ? 44.386  -9.589  -21.361 1.00 42.55  ? 298 LYS C N   1 
ATOM   9553  C CA  . LYS C 1 298 ? 44.576  -8.193  -21.003 1.00 44.80  ? 298 LYS C CA  1 
ATOM   9554  C C   . LYS C 1 298 ? 44.435  -7.332  -22.258 1.00 46.55  ? 298 LYS C C   1 
ATOM   9555  O O   . LYS C 1 298 ? 43.895  -6.223  -22.223 1.00 44.21  ? 298 LYS C O   1 
ATOM   9556  C CB  . LYS C 1 298 ? 45.935  -8.018  -20.306 1.00 52.35  ? 298 LYS C CB  1 
ATOM   9557  C CG  . LYS C 1 298 ? 45.929  -8.412  -18.835 1.00 65.01  ? 298 LYS C CG  1 
ATOM   9558  C CD  . LYS C 1 298 ? 47.211  -8.145  -18.083 1.00 75.81  ? 298 LYS C CD  1 
ATOM   9559  C CE  . LYS C 1 298 ? 48.218  -9.264  -18.242 1.00 89.86  ? 298 LYS C CE  1 
ATOM   9560  N NZ  . LYS C 1 298 ? 49.280  -9.196  -17.208 1.00 95.50  ? 298 LYS C NZ  1 
ATOM   9561  N N   . GLU C 1 299 ? 44.940  -7.881  -23.367 1.00 45.06  ? 299 GLU C N   1 
ATOM   9562  C CA  . GLU C 1 299 ? 45.009  -7.232  -24.659 1.00 47.85  ? 299 GLU C CA  1 
ATOM   9563  C C   . GLU C 1 299 ? 43.601  -7.003  -25.172 1.00 38.82  ? 299 GLU C C   1 
ATOM   9564  O O   . GLU C 1 299 ? 43.255  -5.912  -25.639 1.00 41.20  ? 299 GLU C O   1 
ATOM   9565  C CB  . GLU C 1 299 ? 45.734  -8.125  -25.679 1.00 55.39  ? 299 GLU C CB  1 
ATOM   9566  C CG  . GLU C 1 299 ? 47.202  -8.427  -25.380 1.00 71.85  ? 299 GLU C CG  1 
ATOM   9567  C CD  . GLU C 1 299 ? 47.596  -9.011  -24.022 1.00 84.66  ? 299 GLU C CD  1 
ATOM   9568  O OE1 . GLU C 1 299 ? 48.588  -8.498  -23.455 1.00 101.79 ? 299 GLU C OE1 1 
ATOM   9569  O OE2 . GLU C 1 299 ? 46.934  -9.974  -23.517 1.00 64.17  ? 299 GLU C OE2 1 
ATOM   9570  N N   . GLN C 1 300 ? 42.792  -8.054  -25.123 1.00 34.73  ? 300 GLN C N   1 
ATOM   9571  C CA  . GLN C 1 300 ? 41.414  -7.929  -25.577 1.00 37.27  ? 300 GLN C CA  1 
ATOM   9572  C C   . GLN C 1 300 ? 40.641  -6.936  -24.702 1.00 37.89  ? 300 GLN C C   1 
ATOM   9573  O O   . GLN C 1 300 ? 39.798  -6.177  -25.193 1.00 36.36  ? 300 GLN C O   1 
ATOM   9574  C CB  . GLN C 1 300 ? 40.731  -9.287  -25.526 1.00 41.48  ? 300 GLN C CB  1 
ATOM   9575  C CG  . GLN C 1 300 ? 41.348  -10.316 -26.463 1.00 44.10  ? 300 GLN C CG  1 
ATOM   9576  C CD  . GLN C 1 300 ? 40.616  -11.624 -26.269 1.00 45.21  ? 300 GLN C CD  1 
ATOM   9577  O OE1 . GLN C 1 300 ? 40.414  -12.089 -25.158 1.00 40.91  ? 300 GLN C OE1 1 
ATOM   9578  N NE2 . GLN C 1 300 ? 40.110  -12.172 -27.347 1.00 46.03  ? 300 GLN C NE2 1 
ATOM   9579  N N   . LEU C 1 301 ? 40.921  -6.927  -23.391 1.00 37.40  ? 301 LEU C N   1 
ATOM   9580  C CA  . LEU C 1 301 ? 40.104  -6.106  -22.500 1.00 33.35  ? 301 LEU C CA  1 
ATOM   9581  C C   . LEU C 1 301 ? 40.429  -4.633  -22.730 1.00 37.27  ? 301 LEU C C   1 
ATOM   9582  O O   . LEU C 1 301 ? 39.522  -3.798  -22.793 1.00 37.15  ? 301 LEU C O   1 
ATOM   9583  C CB  . LEU C 1 301 ? 40.341  -6.532  -21.047 1.00 34.33  ? 301 LEU C CB  1 
ATOM   9584  C CG  . LEU C 1 301 ? 39.559  -5.734  -20.004 1.00 33.21  ? 301 LEU C CG  1 
ATOM   9585  C CD1 . LEU C 1 301 ? 38.083  -5.749  -20.306 1.00 36.45  ? 301 LEU C CD1 1 
ATOM   9586  C CD2 . LEU C 1 301 ? 39.822  -6.281  -18.613 1.00 39.00  ? 301 LEU C CD2 1 
ATOM   9587  N N   . GLU C 1 302 ? 41.731  -4.342  -22.875 1.00 40.15  ? 302 GLU C N   1 
ATOM   9588  C CA  . GLU C 1 302 ? 42.228  -2.993  -23.075 1.00 41.40  ? 302 GLU C CA  1 
ATOM   9589  C C   . GLU C 1 302 ? 41.663  -2.394  -24.368 1.00 45.11  ? 302 GLU C C   1 
ATOM   9590  O O   . GLU C 1 302 ? 41.184  -1.257  -24.364 1.00 43.06  ? 302 GLU C O   1 
ATOM   9591  C CB  . GLU C 1 302 ? 43.759  -2.986  -23.037 1.00 45.76  ? 302 GLU C CB  1 
ATOM   9592  C CG  . GLU C 1 302 ? 44.319  -1.569  -23.078 1.00 53.97  ? 302 GLU C CG  1 
ATOM   9593  C CD  . GLU C 1 302 ? 45.728  -1.366  -22.543 1.00 62.67  ? 302 GLU C CD  1 
ATOM   9594  O OE1 . GLU C 1 302 ? 46.124  -0.179  -22.392 1.00 63.22  ? 302 GLU C OE1 1 
ATOM   9595  O OE2 . GLU C 1 302 ? 46.432  -2.385  -22.309 1.00 66.66  ? 302 GLU C OE2 1 
ATOM   9596  N N   . ARG C 1 303 ? 41.643  -3.191  -25.444 1.00 41.99  ? 303 ARG C N   1 
ATOM   9597  C CA  . ARG C 1 303 ? 41.091  -2.765  -26.722 1.00 42.96  ? 303 ARG C CA  1 
ATOM   9598  C C   . ARG C 1 303 ? 39.595  -2.465  -26.593 1.00 42.55  ? 303 ARG C C   1 
ATOM   9599  O O   . ARG C 1 303 ? 39.122  -1.449  -27.119 1.00 40.06  ? 303 ARG C O   1 
ATOM   9600  C CB  . ARG C 1 303 ? 41.329  -3.836  -27.793 1.00 41.19  ? 303 ARG C CB  1 
ATOM   9601  C CG  . ARG C 1 303 ? 40.524  -3.642  -29.070 1.00 41.92  ? 303 ARG C CG  1 
ATOM   9602  C CD  . ARG C 1 303 ? 40.878  -4.717  -30.076 1.00 48.18  ? 303 ARG C CD  1 
ATOM   9603  N NE  . ARG C 1 303 ? 42.180  -4.447  -30.677 1.00 59.75  ? 303 ARG C NE  1 
ATOM   9604  C CZ  . ARG C 1 303 ? 42.406  -3.586  -31.679 1.00 63.73  ? 303 ARG C CZ  1 
ATOM   9605  N NH1 . ARG C 1 303 ? 41.421  -2.888  -32.219 1.00 62.32  ? 303 ARG C NH1 1 
ATOM   9606  N NH2 . ARG C 1 303 ? 43.628  -3.439  -32.155 1.00 61.55  ? 303 ARG C NH2 1 
ATOM   9607  N N   . PHE C 1 304 ? 38.856  -3.362  -25.916 1.00 42.79  ? 304 PHE C N   1 
ATOM   9608  C CA  . PHE C 1 304 ? 37.426  -3.187  -25.700 1.00 36.29  ? 304 PHE C CA  1 
ATOM   9609  C C   . PHE C 1 304 ? 37.160  -1.906  -24.898 1.00 34.71  ? 304 PHE C C   1 
ATOM   9610  O O   . PHE C 1 304 ? 36.277  -1.116  -25.230 1.00 36.73  ? 304 PHE C O   1 
ATOM   9611  C CB  . PHE C 1 304 ? 36.815  -4.414  -25.015 1.00 42.50  ? 304 PHE C CB  1 
ATOM   9612  C CG  . PHE C 1 304 ? 35.336  -4.263  -24.770 1.00 46.38  ? 304 PHE C CG  1 
ATOM   9613  C CD1 . PHE C 1 304 ? 34.426  -4.544  -25.781 1.00 49.28  ? 304 PHE C CD1 1 
ATOM   9614  C CD2 . PHE C 1 304 ? 34.861  -3.732  -23.581 1.00 45.91  ? 304 PHE C CD2 1 
ATOM   9615  C CE1 . PHE C 1 304 ? 33.069  -4.355  -25.596 1.00 48.04  ? 304 PHE C CE1 1 
ATOM   9616  C CE2 . PHE C 1 304 ? 33.500  -3.527  -23.402 1.00 46.53  ? 304 PHE C CE2 1 
ATOM   9617  C CZ  . PHE C 1 304 ? 32.611  -3.846  -24.407 1.00 48.58  ? 304 PHE C CZ  1 
ATOM   9618  N N   . ALA C 1 305 ? 37.972  -1.636  -23.880 1.00 36.73  ? 305 ALA C N   1 
ATOM   9619  C CA  . ALA C 1 305 ? 37.750  -0.451  -23.064 1.00 36.87  ? 305 ALA C CA  1 
ATOM   9620  C C   . ALA C 1 305 ? 37.897  0.822   -23.902 1.00 42.17  ? 305 ALA C C   1 
ATOM   9621  O O   . ALA C 1 305 ? 37.108  1.758   -23.747 1.00 43.92  ? 305 ALA C O   1 
ATOM   9622  C CB  . ALA C 1 305 ? 38.675  -0.438  -21.879 1.00 35.37  ? 305 ALA C CB  1 
ATOM   9623  N N   . TRP C 1 306 ? 38.929  0.855   -24.756 1.00 42.23  ? 306 TRP C N   1 
ATOM   9624  C CA  . TRP C 1 306 ? 39.164  1.969   -25.663 1.00 42.66  ? 306 TRP C CA  1 
ATOM   9625  C C   . TRP C 1 306 ? 37.995  2.129   -26.617 1.00 37.17  ? 306 TRP C C   1 
ATOM   9626  O O   . TRP C 1 306 ? 37.559  3.248   -26.856 1.00 40.05  ? 306 TRP C O   1 
ATOM   9627  C CB  . TRP C 1 306 ? 40.502  1.822   -26.412 1.00 36.18  ? 306 TRP C CB  1 
ATOM   9628  C CG  . TRP C 1 306 ? 41.674  2.190   -25.555 1.00 34.58  ? 306 TRP C CG  1 
ATOM   9629  C CD1 . TRP C 1 306 ? 42.676  1.375   -25.113 1.00 37.09  ? 306 TRP C CD1 1 
ATOM   9630  C CD2 . TRP C 1 306 ? 41.984  3.499   -25.071 1.00 36.11  ? 306 TRP C CD2 1 
ATOM   9631  N NE1 . TRP C 1 306 ? 43.566  2.085   -24.359 1.00 39.44  ? 306 TRP C NE1 1 
ATOM   9632  C CE2 . TRP C 1 306 ? 43.156  3.387   -24.299 1.00 35.02  ? 306 TRP C CE2 1 
ATOM   9633  C CE3 . TRP C 1 306 ? 41.399  4.758   -25.242 1.00 38.68  ? 306 TRP C CE3 1 
ATOM   9634  C CZ2 . TRP C 1 306 ? 43.777  4.496   -23.736 1.00 41.37  ? 306 TRP C CZ2 1 
ATOM   9635  C CZ3 . TRP C 1 306 ? 41.962  5.839   -24.606 1.00 41.96  ? 306 TRP C CZ3 1 
ATOM   9636  C CH2 . TRP C 1 306 ? 43.145  5.709   -23.880 1.00 42.13  ? 306 TRP C CH2 1 
ATOM   9637  N N   . ASP C 1 307 ? 37.538  1.029   -27.211 1.00 37.92  ? 307 ASP C N   1 
ATOM   9638  C CA  . ASP C 1 307 ? 36.422  1.110   -28.145 1.00 42.37  ? 307 ASP C CA  1 
ATOM   9639  C C   . ASP C 1 307 ? 35.215  1.708   -27.424 1.00 45.27  ? 307 ASP C C   1 
ATOM   9640  O O   . ASP C 1 307 ? 34.564  2.617   -27.943 1.00 49.31  ? 307 ASP C O   1 
ATOM   9641  C CB  . ASP C 1 307 ? 36.104  -0.245  -28.782 1.00 44.45  ? 307 ASP C CB  1 
ATOM   9642  C CG  . ASP C 1 307 ? 37.222  -0.789  -29.673 1.00 55.29  ? 307 ASP C CG  1 
ATOM   9643  O OD1 . ASP C 1 307 ? 38.126  -0.005  -30.077 1.00 50.79  ? 307 ASP C OD1 1 
ATOM   9644  O OD2 . ASP C 1 307 ? 37.216  -2.000  -29.932 1.00 54.61  ? 307 ASP C OD2 1 
ATOM   9645  N N   . THR C 1 308 ? 34.982  1.232   -26.195 1.00 40.67  ? 308 THR C N   1 
ATOM   9646  C CA  . THR C 1 308 ? 33.900  1.702   -25.341 1.00 44.43  ? 308 THR C CA  1 
ATOM   9647  C C   . THR C 1 308 ? 34.042  3.208   -25.103 1.00 38.68  ? 308 THR C C   1 
ATOM   9648  O O   . THR C 1 308 ? 33.123  3.985   -25.311 1.00 42.78  ? 308 THR C O   1 
ATOM   9649  C CB  . THR C 1 308 ? 33.912  0.917   -24.014 1.00 43.84  ? 308 THR C CB  1 
ATOM   9650  O OG1 . THR C 1 308 ? 33.426  -0.397  -24.247 1.00 50.56  ? 308 THR C OG1 1 
ATOM   9651  C CG2 . THR C 1 308 ? 33.082  1.530   -22.920 1.00 51.02  ? 308 THR C CG2 1 
ATOM   9652  N N   . LEU C 1 309 ? 35.208  3.616   -24.620 1.00 40.55  ? 309 LEU C N   1 
ATOM   9653  C CA  . LEU C 1 309 ? 35.407  5.015   -24.297 1.00 43.77  ? 309 LEU C CA  1 
ATOM   9654  C C   . LEU C 1 309 ? 35.275  5.858   -25.567 1.00 48.78  ? 309 LEU C C   1 
ATOM   9655  O O   . LEU C 1 309 ? 34.729  6.955   -25.500 1.00 46.53  ? 309 LEU C O   1 
ATOM   9656  C CB  . LEU C 1 309 ? 36.768  5.166   -23.613 1.00 41.58  ? 309 LEU C CB  1 
ATOM   9657  C CG  . LEU C 1 309 ? 36.823  4.589   -22.205 1.00 41.93  ? 309 LEU C CG  1 
ATOM   9658  C CD1 . LEU C 1 309 ? 38.234  4.653   -21.652 1.00 44.83  ? 309 LEU C CD1 1 
ATOM   9659  C CD2 . LEU C 1 309 ? 35.845  5.323   -21.294 1.00 46.46  ? 309 LEU C CD2 1 
ATOM   9660  N N   . ASN C 1 310 ? 35.734  5.347   -26.722 1.00 47.77  ? 310 ASN C N   1 
ATOM   9661  C CA  . ASN C 1 310 ? 35.768  6.165   -27.930 1.00 50.38  ? 310 ASN C CA  1 
ATOM   9662  C C   . ASN C 1 310 ? 34.381  6.196   -28.569 1.00 51.75  ? 310 ASN C C   1 
ATOM   9663  O O   . ASN C 1 310 ? 34.129  7.019   -29.436 1.00 56.93  ? 310 ASN C O   1 
ATOM   9664  C CB  . ASN C 1 310 ? 36.869  5.745   -28.914 1.00 48.01  ? 310 ASN C CB  1 
ATOM   9665  C CG  . ASN C 1 310 ? 38.268  6.165   -28.485 1.00 48.90  ? 310 ASN C CG  1 
ATOM   9666  O OD1 . ASN C 1 310 ? 38.461  7.189   -27.841 1.00 50.59  ? 310 ASN C OD1 1 
ATOM   9667  N ND2 . ASN C 1 310 ? 39.267  5.364   -28.797 1.00 47.43  ? 310 ASN C ND2 1 
ATOM   9668  N N   . SER C 1 311 ? 33.444  5.362   -28.108 1.00 47.58  ? 311 SER C N   1 
ATOM   9669  C CA  . SER C 1 311 ? 32.068  5.484   -28.571 1.00 50.88  ? 311 SER C CA  1 
ATOM   9670  C C   . SER C 1 311 ? 31.221  6.331   -27.602 1.00 50.12  ? 311 SER C C   1 
ATOM   9671  O O   . SER C 1 311 ? 30.011  6.432   -27.762 1.00 48.41  ? 311 SER C O   1 
ATOM   9672  C CB  . SER C 1 311 ? 31.466  4.113   -28.838 1.00 56.42  ? 311 SER C CB  1 
ATOM   9673  O OG  . SER C 1 311 ? 31.280  3.391   -27.630 1.00 69.03  ? 311 SER C OG  1 
ATOM   9674  N N   . GLY C 1 312 ? 31.851  6.960   -26.598 1.00 48.77  ? 312 GLY C N   1 
ATOM   9675  C CA  . GLY C 1 312 ? 31.157  7.838   -25.664 1.00 52.61  ? 312 GLY C CA  1 
ATOM   9676  C C   . GLY C 1 312 ? 30.515  7.088   -24.492 1.00 58.01  ? 312 GLY C C   1 
ATOM   9677  O O   . GLY C 1 312 ? 29.653  7.636   -23.806 1.00 59.56  ? 312 GLY C O   1 
ATOM   9678  N N   . GLN C 1 313 ? 30.927  5.834   -24.249 1.00 48.47  ? 313 GLN C N   1 
ATOM   9679  C CA  . GLN C 1 313 ? 30.276  5.025   -23.232 1.00 48.12  ? 313 GLN C CA  1 
ATOM   9680  C C   . GLN C 1 313 ? 31.103  5.154   -21.964 1.00 45.46  ? 313 GLN C C   1 
ATOM   9681  O O   . GLN C 1 313 ? 32.278  5.492   -22.041 1.00 41.74  ? 313 GLN C O   1 
ATOM   9682  C CB  . GLN C 1 313 ? 30.164  3.559   -23.651 1.00 51.39  ? 313 GLN C CB  1 
ATOM   9683  C CG  . GLN C 1 313 ? 29.365  3.301   -24.921 1.00 61.83  ? 313 GLN C CG  1 
ATOM   9684  C CD  . GLN C 1 313 ? 27.889  3.444   -24.667 1.00 71.07  ? 313 GLN C CD  1 
ATOM   9685  O OE1 . GLN C 1 313 ? 27.208  2.495   -24.288 1.00 76.52  ? 313 GLN C OE1 1 
ATOM   9686  N NE2 . GLN C 1 313 ? 27.394  4.658   -24.814 1.00 84.83  ? 313 GLN C NE2 1 
ATOM   9687  N N   . VAL C 1 314 ? 30.492  4.857   -20.813 1.00 43.15  ? 314 VAL C N   1 
ATOM   9688  C CA  . VAL C 1 314 ? 31.226  4.823   -19.560 1.00 50.56  ? 314 VAL C CA  1 
ATOM   9689  C C   . VAL C 1 314 ? 31.537  3.367   -19.220 1.00 50.90  ? 314 VAL C C   1 
ATOM   9690  O O   . VAL C 1 314 ? 30.845  2.450   -19.662 1.00 49.68  ? 314 VAL C O   1 
ATOM   9691  C CB  . VAL C 1 314 ? 30.451  5.529   -18.432 1.00 54.62  ? 314 VAL C CB  1 
ATOM   9692  C CG1 . VAL C 1 314 ? 29.992  6.915   -18.876 1.00 54.98  ? 314 VAL C CG1 1 
ATOM   9693  C CG2 . VAL C 1 314 ? 29.280  4.694   -17.935 1.00 56.59  ? 314 VAL C CG2 1 
ATOM   9694  N N   . ILE C 1 315 ? 32.631  3.178   -18.485 1.00 43.75  ? 315 ILE C N   1 
ATOM   9695  C CA  . ILE C 1 315 ? 32.968  1.884   -17.945 1.00 40.41  ? 315 ILE C CA  1 
ATOM   9696  C C   . ILE C 1 315 ? 32.408  1.857   -16.530 1.00 39.81  ? 315 ILE C C   1 
ATOM   9697  O O   . ILE C 1 315 ? 32.815  2.642   -15.683 1.00 38.43  ? 315 ILE C O   1 
ATOM   9698  C CB  . ILE C 1 315 ? 34.489  1.667   -18.011 1.00 43.07  ? 315 ILE C CB  1 
ATOM   9699  C CG1 . ILE C 1 315 ? 34.911  1.460   -19.473 1.00 45.17  ? 315 ILE C CG1 1 
ATOM   9700  C CG2 . ILE C 1 315 ? 34.941  0.516   -17.132 1.00 39.38  ? 315 ILE C CG2 1 
ATOM   9701  C CD1 . ILE C 1 315 ? 36.364  1.586   -19.688 1.00 46.89  ? 315 ILE C CD1 1 
ATOM   9702  N N   . PRO C 1 316 ? 31.425  0.984   -16.254 1.00 36.99  ? 316 PRO C N   1 
ATOM   9703  C CA  . PRO C 1 316 ? 30.714  1.034   -14.977 1.00 35.64  ? 316 PRO C CA  1 
ATOM   9704  C C   . PRO C 1 316 ? 31.582  0.446   -13.877 1.00 31.14  ? 316 PRO C C   1 
ATOM   9705  O O   . PRO C 1 316 ? 32.383  -0.457  -14.113 1.00 31.28  ? 316 PRO C O   1 
ATOM   9706  C CB  . PRO C 1 316 ? 29.435  0.260   -15.319 1.00 37.77  ? 316 PRO C CB  1 
ATOM   9707  C CG  . PRO C 1 316 ? 29.934  -0.797  -16.268 1.00 39.86  ? 316 PRO C CG  1 
ATOM   9708  C CD  . PRO C 1 316 ? 30.921  -0.065  -17.148 1.00 33.44  ? 316 PRO C CD  1 
ATOM   9709  N N   . GLY C 1 317 ? 31.403  1.010   -12.680 1.00 30.08  ? 317 GLY C N   1 
ATOM   9710  C CA  . GLY C 1 317 ? 32.053  0.565   -11.474 1.00 31.05  ? 317 GLY C CA  1 
ATOM   9711  C C   . GLY C 1 317 ? 33.338  1.333   -11.205 1.00 32.64  ? 317 GLY C C   1 
ATOM   9712  O O   . GLY C 1 317 ? 34.051  1.017   -10.258 1.00 32.72  ? 317 GLY C O   1 
ATOM   9713  N N   . TYR C 1 318 ? 33.692  2.249   -12.116 1.00 32.70  ? 318 TYR C N   1 
ATOM   9714  C CA  . TYR C 1 318 ? 34.924  3.009   -11.986 1.00 32.91  ? 318 TYR C CA  1 
ATOM   9715  C C   . TYR C 1 318 ? 34.533  4.478   -11.839 1.00 33.21  ? 318 TYR C C   1 
ATOM   9716  O O   . TYR C 1 318 ? 33.559  4.929   -12.434 1.00 36.38  ? 318 TYR C O   1 
ATOM   9717  C CB  . TYR C 1 318 ? 35.908  2.697   -13.136 1.00 36.64  ? 318 TYR C CB  1 
ATOM   9718  C CG  . TYR C 1 318 ? 36.583  1.356   -12.994 1.00 32.93  ? 318 TYR C CG  1 
ATOM   9719  C CD1 . TYR C 1 318 ? 35.872  0.179   -13.179 1.00 36.27  ? 318 TYR C CD1 1 
ATOM   9720  C CD2 . TYR C 1 318 ? 37.877  1.247   -12.536 1.00 35.01  ? 318 TYR C CD2 1 
ATOM   9721  C CE1 . TYR C 1 318 ? 36.436  -1.062  -12.949 1.00 32.25  ? 318 TYR C CE1 1 
ATOM   9722  C CE2 . TYR C 1 318 ? 38.459  0.012   -12.300 1.00 33.52  ? 318 TYR C CE2 1 
ATOM   9723  C CZ  . TYR C 1 318 ? 37.745  -1.150  -12.518 1.00 33.36  ? 318 TYR C CZ  1 
ATOM   9724  O OH  . TYR C 1 318 ? 38.317  -2.372  -12.224 1.00 32.13  ? 318 TYR C OH  1 
ATOM   9725  N N   . GLY C 1 319 ? 35.298  5.218   -11.025 1.00 39.78  ? 319 GLY C N   1 
ATOM   9726  C CA  . GLY C 1 319 ? 35.079  6.647   -10.839 1.00 37.32  ? 319 GLY C CA  1 
ATOM   9727  C C   . GLY C 1 319 ? 34.181  6.880   -9.631  1.00 44.99  ? 319 GLY C C   1 
ATOM   9728  O O   . GLY C 1 319 ? 33.646  5.918   -9.064  1.00 41.19  ? 319 GLY C O   1 
ATOM   9729  N N   . HIS C 1 320 ? 34.043  8.149   -9.234  1.00 43.31  ? 320 HIS C N   1 
ATOM   9730  C CA  . HIS C 1 320 ? 33.287  8.493   -8.037  1.00 43.07  ? 320 HIS C CA  1 
ATOM   9731  C C   . HIS C 1 320 ? 33.179  10.011  -7.918  1.00 46.57  ? 320 HIS C C   1 
ATOM   9732  O O   . HIS C 1 320 ? 34.086  10.715  -8.339  1.00 43.02  ? 320 HIS C O   1 
ATOM   9733  C CB  . HIS C 1 320 ? 33.946  7.909   -6.778  1.00 44.49  ? 320 HIS C CB  1 
ATOM   9734  C CG  . HIS C 1 320 ? 33.004  7.806   -5.627  1.00 49.19  ? 320 HIS C CG  1 
ATOM   9735  N ND1 . HIS C 1 320 ? 32.852  8.791   -4.668  1.00 49.00  ? 320 HIS C ND1 1 
ATOM   9736  C CD2 . HIS C 1 320 ? 32.103  6.850   -5.342  1.00 48.35  ? 320 HIS C CD2 1 
ATOM   9737  C CE1 . HIS C 1 320 ? 31.902  8.419   -3.819  1.00 52.79  ? 320 HIS C CE1 1 
ATOM   9738  N NE2 . HIS C 1 320 ? 31.446  7.229   -4.196  1.00 51.80  ? 320 HIS C NE2 1 
ATOM   9739  N N   . ALA C 1 321 ? 32.093  10.497  -7.305  1.00 45.79  ? 321 ALA C N   1 
ATOM   9740  C CA  . ALA C 1 321 ? 31.913  11.928  -7.091  1.00 53.50  ? 321 ALA C CA  1 
ATOM   9741  C C   . ALA C 1 321 ? 33.033  12.513  -6.228  1.00 51.89  ? 321 ALA C C   1 
ATOM   9742  O O   . ALA C 1 321 ? 33.405  13.651  -6.452  1.00 55.33  ? 321 ALA C O   1 
ATOM   9743  C CB  . ALA C 1 321 ? 30.552  12.239  -6.494  1.00 45.81  ? 321 ALA C CB  1 
ATOM   9744  N N   . VAL C 1 322 ? 33.582  11.766  -5.260  1.00 56.78  ? 322 VAL C N   1 
ATOM   9745  C CA  . VAL C 1 322 ? 34.504  12.371  -4.302  1.00 57.51  ? 322 VAL C CA  1 
ATOM   9746  C C   . VAL C 1 322 ? 35.748  11.504  -4.066  1.00 55.76  ? 322 VAL C C   1 
ATOM   9747  O O   . VAL C 1 322 ? 36.824  12.062  -3.854  1.00 55.91  ? 322 VAL C O   1 
ATOM   9748  C CB  . VAL C 1 322 ? 33.773  12.781  -2.994  1.00 71.88  ? 322 VAL C CB  1 
ATOM   9749  C CG1 . VAL C 1 322 ? 32.651  11.831  -2.599  1.00 66.00  ? 322 VAL C CG1 1 
ATOM   9750  C CG2 . VAL C 1 322 ? 34.726  12.980  -1.819  1.00 76.31  ? 322 VAL C CG2 1 
ATOM   9751  N N   . LEU C 1 323 ? 35.636  10.161  -4.107  1.00 47.11  ? 323 LEU C N   1 
ATOM   9752  C CA  . LEU C 1 323 ? 36.809  9.296   -3.954  1.00 49.00  ? 323 LEU C CA  1 
ATOM   9753  C C   . LEU C 1 323 ? 37.845  9.601   -5.043  1.00 45.88  ? 323 LEU C C   1 
ATOM   9754  O O   . LEU C 1 323 ? 37.442  9.889   -6.165  1.00 46.40  ? 323 LEU C O   1 
ATOM   9755  C CB  . LEU C 1 323 ? 36.405  7.819   -4.077  1.00 52.33  ? 323 LEU C CB  1 
ATOM   9756  C CG  . LEU C 1 323 ? 35.976  7.063   -2.817  1.00 61.18  ? 323 LEU C CG  1 
ATOM   9757  C CD1 . LEU C 1 323 ? 36.738  7.516   -1.587  1.00 57.23  ? 323 LEU C CD1 1 
ATOM   9758  C CD2 . LEU C 1 323 ? 34.483  7.178   -2.582  1.00 69.98  ? 323 LEU C CD2 1 
ATOM   9759  N N   . ARG C 1 324 ? 39.140  9.445   -4.710  1.00 44.77  ? 324 ARG C N   1 
ATOM   9760  C CA  . ARG C 1 324 ? 40.260  9.574   -5.636  1.00 50.36  ? 324 ARG C CA  1 
ATOM   9761  C C   . ARG C 1 324 ? 41.273  8.432   -5.491  1.00 50.22  ? 324 ARG C C   1 
ATOM   9762  O O   . ARG C 1 324 ? 42.338  8.465   -6.095  1.00 58.24  ? 324 ARG C O   1 
ATOM   9763  C CB  . ARG C 1 324 ? 40.968  10.921  -5.421  1.00 53.78  ? 324 ARG C CB  1 
ATOM   9764  C CG  . ARG C 1 324 ? 40.112  12.150  -5.711  1.00 49.46  ? 324 ARG C CG  1 
ATOM   9765  C CD  . ARG C 1 324 ? 39.580  12.220  -7.136  1.00 54.20  ? 324 ARG C CD  1 
ATOM   9766  N NE  . ARG C 1 324 ? 38.679  13.364  -7.352  1.00 52.81  ? 324 ARG C NE  1 
ATOM   9767  C CZ  . ARG C 1 324 ? 37.373  13.299  -7.589  1.00 53.14  ? 324 ARG C CZ  1 
ATOM   9768  N NH1 . ARG C 1 324 ? 36.707  12.156  -7.492  1.00 48.91  ? 324 ARG C NH1 1 
ATOM   9769  N NH2 . ARG C 1 324 ? 36.717  14.404  -7.906  1.00 53.17  ? 324 ARG C NH2 1 
ATOM   9770  N N   . VAL C 1 325 ? 40.980  7.416   -4.681  1.00 48.60  ? 325 VAL C N   1 
ATOM   9771  C CA  . VAL C 1 325 ? 41.752  6.180   -4.684  1.00 43.05  ? 325 VAL C CA  1 
ATOM   9772  C C   . VAL C 1 325 ? 40.780  4.999   -4.833  1.00 38.25  ? 325 VAL C C   1 
ATOM   9773  O O   . VAL C 1 325 ? 39.565  5.191   -4.877  1.00 40.84  ? 325 VAL C O   1 
ATOM   9774  C CB  . VAL C 1 325 ? 42.616  6.037   -3.411  1.00 42.68  ? 325 VAL C CB  1 
ATOM   9775  C CG1 . VAL C 1 325 ? 43.818  6.969   -3.420  1.00 46.37  ? 325 VAL C CG1 1 
ATOM   9776  C CG2 . VAL C 1 325 ? 41.776  6.217   -2.137  1.00 42.59  ? 325 VAL C CG2 1 
ATOM   9777  N N   . THR C 1 326 ? 41.325  3.775   -4.866  1.00 39.16  ? 326 THR C N   1 
ATOM   9778  C CA  . THR C 1 326 ? 40.512  2.568   -4.865  1.00 40.72  ? 326 THR C CA  1 
ATOM   9779  C C   . THR C 1 326 ? 39.655  2.523   -3.591  1.00 40.64  ? 326 THR C C   1 
ATOM   9780  O O   . THR C 1 326 ? 40.147  2.648   -2.465  1.00 34.63  ? 326 THR C O   1 
ATOM   9781  C CB  . THR C 1 326 ? 41.428  1.352   -5.048  1.00 41.05  ? 326 THR C CB  1 
ATOM   9782  O OG1 . THR C 1 326 ? 42.048  1.474   -6.333  1.00 42.20  ? 326 THR C OG1 1 
ATOM   9783  C CG2 . THR C 1 326 ? 40.706  0.027   -4.938  1.00 39.87  ? 326 THR C CG2 1 
ATOM   9784  N N   . ASP C 1 327 ? 38.347  2.344   -3.786  1.00 37.54  ? 327 ASP C N   1 
ATOM   9785  C CA  . ASP C 1 327 ? 37.389  2.311   -2.698  1.00 32.17  ? 327 ASP C CA  1 
ATOM   9786  C C   . ASP C 1 327 ? 37.767  1.198   -1.733  1.00 30.82  ? 327 ASP C C   1 
ATOM   9787  O O   . ASP C 1 327 ? 37.873  0.024   -2.093  1.00 33.61  ? 327 ASP C O   1 
ATOM   9788  C CB  . ASP C 1 327 ? 35.978  2.190   -3.279  1.00 33.66  ? 327 ASP C CB  1 
ATOM   9789  C CG  . ASP C 1 327 ? 34.814  2.397   -2.322  1.00 31.05  ? 327 ASP C CG  1 
ATOM   9790  O OD1 . ASP C 1 327 ? 35.029  2.382   -1.092  1.00 35.05  ? 327 ASP C OD1 1 
ATOM   9791  O OD2 . ASP C 1 327 ? 33.692  2.601   -2.827  1.00 38.85  ? 327 ASP C OD2 1 
ATOM   9792  N N   . PRO C 1 328 ? 38.011  1.501   -0.442  1.00 29.95  ? 328 PRO C N   1 
ATOM   9793  C CA  . PRO C 1 328 ? 38.249  0.428   0.524   1.00 32.48  ? 328 PRO C CA  1 
ATOM   9794  C C   . PRO C 1 328 ? 37.098  -0.585  0.648   1.00 30.57  ? 328 PRO C C   1 
ATOM   9795  O O   . PRO C 1 328 ? 37.308  -1.714  1.076   1.00 28.99  ? 328 PRO C O   1 
ATOM   9796  C CB  . PRO C 1 328 ? 38.478  1.164   1.844   1.00 30.84  ? 328 PRO C CB  1 
ATOM   9797  C CG  . PRO C 1 328 ? 37.861  2.512   1.615   1.00 34.42  ? 328 PRO C CG  1 
ATOM   9798  C CD  . PRO C 1 328 ? 38.066  2.829   0.151   1.00 31.70  ? 328 PRO C CD  1 
ATOM   9799  N N   . ARG C 1 329 ? 35.877  -0.195  0.278   1.00 29.81  ? 329 ARG C N   1 
ATOM   9800  C CA  . ARG C 1 329 ? 34.768  -1.148  0.230   1.00 31.16  ? 329 ARG C CA  1 
ATOM   9801  C C   . ARG C 1 329 ? 34.977  -2.136  -0.922  1.00 31.44  ? 329 ARG C C   1 
ATOM   9802  O O   . ARG C 1 329 ? 34.501  -3.254  -0.835  1.00 32.68  ? 329 ARG C O   1 
ATOM   9803  C CB  . ARG C 1 329 ? 33.462  -0.376  0.060   1.00 30.31  ? 329 ARG C CB  1 
ATOM   9804  C CG  . ARG C 1 329 ? 33.131  0.495   1.267   1.00 30.00  ? 329 ARG C CG  1 
ATOM   9805  C CD  . ARG C 1 329 ? 32.022  1.483   1.066   1.00 27.85  ? 329 ARG C CD  1 
ATOM   9806  N NE  . ARG C 1 329 ? 32.151  2.289   -0.114  1.00 29.37  ? 329 ARG C NE  1 
ATOM   9807  C CZ  . ARG C 1 329 ? 31.194  3.040   -0.651  1.00 30.92  ? 329 ARG C CZ  1 
ATOM   9808  N NH1 . ARG C 1 329 ? 30.024  3.131   -0.061  1.00 30.59  ? 329 ARG C NH1 1 
ATOM   9809  N NH2 . ARG C 1 329 ? 31.427  3.743   -1.752  1.00 33.38  ? 329 ARG C NH2 1 
ATOM   9810  N N   . TYR C 1 330 ? 35.636  -1.715  -2.028  1.00 31.84  ? 330 TYR C N   1 
ATOM   9811  C CA  . TYR C 1 330 ? 35.982  -2.637  -3.123  1.00 29.92  ? 330 TYR C CA  1 
ATOM   9812  C C   . TYR C 1 330 ? 37.037  -3.645  -2.661  1.00 30.12  ? 330 TYR C C   1 
ATOM   9813  O O   . TYR C 1 330 ? 36.947  -4.850  -2.920  1.00 30.48  ? 330 TYR C O   1 
ATOM   9814  C CB  . TYR C 1 330 ? 36.479  -1.850  -4.346  1.00 35.09  ? 330 TYR C CB  1 
ATOM   9815  C CG  . TYR C 1 330 ? 36.960  -2.675  -5.515  1.00 34.77  ? 330 TYR C CG  1 
ATOM   9816  C CD1 . TYR C 1 330 ? 38.264  -3.141  -5.571  1.00 38.27  ? 330 TYR C CD1 1 
ATOM   9817  C CD2 . TYR C 1 330 ? 36.115  -2.986  -6.571  1.00 34.75  ? 330 TYR C CD2 1 
ATOM   9818  C CE1 . TYR C 1 330 ? 38.720  -3.878  -6.656  1.00 37.28  ? 330 TYR C CE1 1 
ATOM   9819  C CE2 . TYR C 1 330 ? 36.549  -3.707  -7.669  1.00 32.02  ? 330 TYR C CE2 1 
ATOM   9820  C CZ  . TYR C 1 330 ? 37.859  -4.162  -7.701  1.00 35.66  ? 330 TYR C CZ  1 
ATOM   9821  O OH  . TYR C 1 330 ? 38.337  -4.918  -8.727  1.00 37.04  ? 330 TYR C OH  1 
ATOM   9822  N N   . VAL C 1 331 ? 38.037  -3.138  -1.935  1.00 32.78  ? 331 VAL C N   1 
ATOM   9823  C CA  . VAL C 1 331 ? 39.172  -3.927  -1.500  1.00 31.41  ? 331 VAL C CA  1 
ATOM   9824  C C   . VAL C 1 331 ? 38.663  -5.051  -0.593  1.00 30.60  ? 331 VAL C C   1 
ATOM   9825  O O   . VAL C 1 331 ? 39.116  -6.187  -0.698  1.00 29.17  ? 331 VAL C O   1 
ATOM   9826  C CB  . VAL C 1 331 ? 40.235  -3.037  -0.805  1.00 35.93  ? 331 VAL C CB  1 
ATOM   9827  C CG1 . VAL C 1 331 ? 41.326  -3.850  -0.132  1.00 40.37  ? 331 VAL C CG1 1 
ATOM   9828  C CG2 . VAL C 1 331 ? 40.865  -2.010  -1.753  1.00 38.26  ? 331 VAL C CG2 1 
ATOM   9829  N N   . ALA C 1 332 ? 37.735  -4.753  0.333   1.00 30.20  ? 332 ALA C N   1 
ATOM   9830  C CA  . ALA C 1 332 ? 37.265  -5.773  1.261   1.00 29.20  ? 332 ALA C CA  1 
ATOM   9831  C C   . ALA C 1 332 ? 36.472  -6.855  0.530   1.00 29.43  ? 332 ALA C C   1 
ATOM   9832  O O   . ALA C 1 332 ? 36.519  -8.020  0.913   1.00 28.09  ? 332 ALA C O   1 
ATOM   9833  C CB  . ALA C 1 332 ? 36.442  -5.140  2.346   1.00 32.30  ? 332 ALA C CB  1 
ATOM   9834  N N   . GLN C 1 333 ? 35.720  -6.474  -0.511  1.00 28.36  ? 333 GLN C N   1 
ATOM   9835  C CA  . GLN C 1 333 ? 34.972  -7.441  -1.310  1.00 29.55  ? 333 GLN C CA  1 
ATOM   9836  C C   . GLN C 1 333 ? 35.940  -8.314  -2.106  1.00 31.43  ? 333 GLN C C   1 
ATOM   9837  O O   . GLN C 1 333 ? 35.723  -9.510  -2.297  1.00 32.30  ? 333 GLN C O   1 
ATOM   9838  C CB  . GLN C 1 333 ? 34.010  -6.698  -2.241  1.00 31.60  ? 333 GLN C CB  1 
ATOM   9839  C CG  . GLN C 1 333 ? 32.859  -6.049  -1.460  1.00 35.25  ? 333 GLN C CG  1 
ATOM   9840  C CD  . GLN C 1 333 ? 31.888  -5.405  -2.408  1.00 33.91  ? 333 GLN C CD  1 
ATOM   9841  O OE1 . GLN C 1 333 ? 30.871  -5.999  -2.739  1.00 41.91  ? 333 GLN C OE1 1 
ATOM   9842  N NE2 . GLN C 1 333 ? 32.217  -4.211  -2.884  1.00 35.25  ? 333 GLN C NE2 1 
ATOM   9843  N N   . ARG C 1 334 ? 37.029  -7.709  -2.566  1.00 32.88  ? 334 ARG C N   1 
ATOM   9844  C CA  . ARG C 1 334 ? 38.051  -8.464  -3.267  1.00 30.10  ? 334 ARG C CA  1 
ATOM   9845  C C   . ARG C 1 334 ? 38.633  -9.527  -2.346  1.00 28.97  ? 334 ARG C C   1 
ATOM   9846  O O   . ARG C 1 334 ? 38.790  -10.688 -2.719  1.00 35.02  ? 334 ARG C O   1 
ATOM   9847  C CB  . ARG C 1 334 ? 39.124  -7.506  -3.778  1.00 31.61  ? 334 ARG C CB  1 
ATOM   9848  C CG  . ARG C 1 334 ? 40.255  -8.190  -4.537  1.00 32.98  ? 334 ARG C CG  1 
ATOM   9849  C CD  . ARG C 1 334 ? 41.190  -7.188  -5.156  1.00 34.06  ? 334 ARG C CD  1 
ATOM   9850  N NE  . ARG C 1 334 ? 42.382  -7.855  -5.649  1.00 35.62  ? 334 ARG C NE  1 
ATOM   9851  C CZ  . ARG C 1 334 ? 42.448  -8.688  -6.681  1.00 38.93  ? 334 ARG C CZ  1 
ATOM   9852  N NH1 . ARG C 1 334 ? 41.435  -8.834  -7.529  1.00 34.41  ? 334 ARG C NH1 1 
ATOM   9853  N NH2 . ARG C 1 334 ? 43.571  -9.365  -6.878  1.00 38.13  ? 334 ARG C NH2 1 
ATOM   9854  N N   . ASP C 1 335 ? 38.956  -9.118  -1.125  1.00 34.79  ? 335 ASP C N   1 
ATOM   9855  C CA  . ASP C 1 335 ? 39.516  -10.032 -0.147  1.00 35.34  ? 335 ASP C CA  1 
ATOM   9856  C C   . ASP C 1 335 ? 38.556  -11.199 0.084   1.00 35.15  ? 335 ASP C C   1 
ATOM   9857  O O   . ASP C 1 335 ? 38.959  -12.354 0.158   1.00 32.49  ? 335 ASP C O   1 
ATOM   9858  C CB  . ASP C 1 335 ? 39.837  -9.292  1.153   1.00 36.86  ? 335 ASP C CB  1 
ATOM   9859  C CG  . ASP C 1 335 ? 40.390  -10.234 2.213   1.00 43.19  ? 335 ASP C CG  1 
ATOM   9860  O OD1 . ASP C 1 335 ? 41.458  -10.816 1.975   1.00 46.39  ? 335 ASP C OD1 1 
ATOM   9861  O OD2 . ASP C 1 335 ? 39.719  -10.436 3.244   1.00 43.02  ? 335 ASP C OD2 1 
ATOM   9862  N N   . PHE C 1 336 ? 37.260  -10.906 0.215   1.00 33.73  ? 336 PHE C N   1 
ATOM   9863  C CA  . PHE C 1 336 ? 36.272  -11.965 0.392   1.00 30.71  ? 336 PHE C CA  1 
ATOM   9864  C C   . PHE C 1 336 ? 36.300  -12.907 -0.823  1.00 28.39  ? 336 PHE C C   1 
ATOM   9865  O O   . PHE C 1 336 ? 36.285  -14.111 -0.675  1.00 29.07  ? 336 PHE C O   1 
ATOM   9866  C CB  . PHE C 1 336 ? 34.894  -11.321 0.621   1.00 32.83  ? 336 PHE C CB  1 
ATOM   9867  C CG  . PHE C 1 336 ? 33.810  -12.308 0.923   1.00 32.47  ? 336 PHE C CG  1 
ATOM   9868  C CD1 . PHE C 1 336 ? 33.202  -13.002 -0.103  1.00 30.94  ? 336 PHE C CD1 1 
ATOM   9869  C CD2 . PHE C 1 336 ? 33.475  -12.605 2.237   1.00 34.29  ? 336 PHE C CD2 1 
ATOM   9870  C CE1 . PHE C 1 336 ? 32.235  -13.945 0.169   1.00 28.42  ? 336 PHE C CE1 1 
ATOM   9871  C CE2 . PHE C 1 336 ? 32.501  -13.555 2.507   1.00 39.79  ? 336 PHE C CE2 1 
ATOM   9872  C CZ  . PHE C 1 336 ? 31.897  -14.234 1.470   1.00 33.78  ? 336 PHE C CZ  1 
ATOM   9873  N N   . ALA C 1 337 ? 36.345  -12.361 -2.040  1.00 28.87  ? 337 ALA C N   1 
ATOM   9874  C CA  . ALA C 1 337 ? 36.332  -13.160 -3.263  1.00 29.62  ? 337 ALA C CA  1 
ATOM   9875  C C   . ALA C 1 337 ? 37.577  -14.044 -3.385  1.00 28.15  ? 337 ALA C C   1 
ATOM   9876  O O   . ALA C 1 337 ? 37.489  -15.228 -3.734  1.00 31.38  ? 337 ALA C O   1 
ATOM   9877  C CB  . ALA C 1 337 ? 36.223  -12.244 -4.446  1.00 29.95  ? 337 ALA C CB  1 
ATOM   9878  N N   . LEU C 1 338 ? 38.732  -13.465 -3.097  1.00 31.94  ? 338 LEU C N   1 
ATOM   9879  C CA  . LEU C 1 338 ? 39.983  -14.218 -3.178  1.00 37.11  ? 338 LEU C CA  1 
ATOM   9880  C C   . LEU C 1 338 ? 39.959  -15.362 -2.183  1.00 39.35  ? 338 LEU C C   1 
ATOM   9881  O O   . LEU C 1 338 ? 40.456  -16.412 -2.471  1.00 39.81  ? 338 LEU C O   1 
ATOM   9882  C CB  . LEU C 1 338 ? 41.140  -13.295 -2.838  1.00 34.75  ? 338 LEU C CB  1 
ATOM   9883  C CG  . LEU C 1 338 ? 41.547  -12.328 -3.935  1.00 38.29  ? 338 LEU C CG  1 
ATOM   9884  C CD1 . LEU C 1 338 ? 42.553  -11.349 -3.373  1.00 37.64  ? 338 LEU C CD1 1 
ATOM   9885  C CD2 . LEU C 1 338 ? 42.121  -13.104 -5.122  1.00 43.70  ? 338 LEU C CD2 1 
ATOM   9886  N N   . LYS C 1 339 ? 39.351  -15.143 -1.018  1.00 37.32  ? 339 LYS C N   1 
ATOM   9887  C CA  . LYS C 1 339 ? 39.251  -16.173 -0.013  1.00 40.28  ? 339 LYS C CA  1 
ATOM   9888  C C   . LYS C 1 339 ? 38.208  -17.213 -0.434  1.00 43.14  ? 339 LYS C C   1 
ATOM   9889  O O   . LYS C 1 339 ? 38.461  -18.397 -0.298  1.00 43.37  ? 339 LYS C O   1 
ATOM   9890  C CB  . LYS C 1 339 ? 38.935  -15.454 1.303   1.00 49.01  ? 339 LYS C CB  1 
ATOM   9891  C CG  . LYS C 1 339 ? 39.175  -16.193 2.608   1.00 64.38  ? 339 LYS C CG  1 
ATOM   9892  C CD  . LYS C 1 339 ? 39.040  -15.235 3.802   1.00 68.60  ? 339 LYS C CD  1 
ATOM   9893  C CE  . LYS C 1 339 ? 38.561  -15.900 5.077   1.00 69.10  ? 339 LYS C CE  1 
ATOM   9894  N NZ  . LYS C 1 339 ? 38.226  -14.882 6.104   1.00 66.33  ? 339 LYS C NZ  1 
ATOM   9895  N N   . HIS C 1 340 ? 37.018  -16.818 -0.921  1.00 38.28  ? 340 HIS C N   1 
ATOM   9896  C CA  . HIS C 1 340 ? 35.926  -17.790 -1.005  1.00 34.82  ? 340 HIS C CA  1 
ATOM   9897  C C   . HIS C 1 340 ? 35.533  -18.191 -2.423  1.00 32.27  ? 340 HIS C C   1 
ATOM   9898  O O   . HIS C 1 340 ? 34.881  -19.206 -2.546  1.00 33.76  ? 340 HIS C O   1 
ATOM   9899  C CB  . HIS C 1 340 ? 34.666  -17.320 -0.277  1.00 36.73  ? 340 HIS C CB  1 
ATOM   9900  C CG  . HIS C 1 340 ? 34.895  -16.988 1.156   1.00 38.71  ? 340 HIS C CG  1 
ATOM   9901  N ND1 . HIS C 1 340 ? 35.330  -17.890 2.097   1.00 42.32  ? 340 HIS C ND1 1 
ATOM   9902  C CD2 . HIS C 1 340 ? 34.797  -15.815 1.790   1.00 41.00  ? 340 HIS C CD2 1 
ATOM   9903  C CE1 . HIS C 1 340 ? 35.457  -17.285 3.272   1.00 45.75  ? 340 HIS C CE1 1 
ATOM   9904  N NE2 . HIS C 1 340 ? 35.139  -16.017 3.107   1.00 44.62  ? 340 HIS C NE2 1 
ATOM   9905  N N   . LEU C 1 341 ? 35.852  -17.432 -3.483  1.00 31.15  ? 341 LEU C N   1 
ATOM   9906  C CA  . LEU C 1 341 ? 35.492  -17.892 -4.824  1.00 33.76  ? 341 LEU C CA  1 
ATOM   9907  C C   . LEU C 1 341 ? 36.559  -17.501 -5.852  1.00 36.29  ? 341 LEU C C   1 
ATOM   9908  O O   . LEU C 1 341 ? 36.257  -16.872 -6.872  1.00 38.57  ? 341 LEU C O   1 
ATOM   9909  C CB  . LEU C 1 341 ? 34.099  -17.335 -5.168  1.00 35.13  ? 341 LEU C CB  1 
ATOM   9910  C CG  . LEU C 1 341 ? 33.925  -15.829 -4.971  1.00 32.30  ? 341 LEU C CG  1 
ATOM   9911  C CD1 . LEU C 1 341 ? 33.331  -15.170 -6.181  1.00 33.73  ? 341 LEU C CD1 1 
ATOM   9912  C CD2 . LEU C 1 341 ? 33.127  -15.513 -3.735  1.00 34.78  ? 341 LEU C CD2 1 
ATOM   9913  N N   . PRO C 1 342 ? 37.858  -17.845 -5.637  1.00 37.39  ? 342 PRO C N   1 
ATOM   9914  C CA  . PRO C 1 342 ? 38.923  -17.400 -6.547  1.00 38.14  ? 342 PRO C CA  1 
ATOM   9915  C C   . PRO C 1 342 ? 38.764  -17.883 -7.990  1.00 36.92  ? 342 PRO C C   1 
ATOM   9916  O O   . PRO C 1 342 ? 39.263  -17.252 -8.921  1.00 39.48  ? 342 PRO C O   1 
ATOM   9917  C CB  . PRO C 1 342 ? 40.224  -17.984 -5.950  1.00 40.68  ? 342 PRO C CB  1 
ATOM   9918  C CG  . PRO C 1 342 ? 39.774  -19.054 -4.940  1.00 41.80  ? 342 PRO C CG  1 
ATOM   9919  C CD  . PRO C 1 342 ? 38.364  -18.658 -4.516  1.00 37.80  ? 342 PRO C CD  1 
ATOM   9920  N N   . ASP C 1 343 ? 38.052  -18.992 -8.170  1.00 37.17  ? 343 ASP C N   1 
ATOM   9921  C CA  . ASP C 1 343 ? 37.985  -19.663 -9.464  1.00 45.98  ? 343 ASP C CA  1 
ATOM   9922  C C   . ASP C 1 343 ? 36.763  -19.207 -10.268 1.00 43.14  ? 343 ASP C C   1 
ATOM   9923  O O   . ASP C 1 343 ? 36.552  -19.658 -11.383 1.00 37.24  ? 343 ASP C O   1 
ATOM   9924  C CB  . ASP C 1 343 ? 37.947  -21.189 -9.275  1.00 48.57  ? 343 ASP C CB  1 
ATOM   9925  C CG  . ASP C 1 343 ? 39.204  -21.760 -8.602  1.00 52.60  ? 343 ASP C CG  1 
ATOM   9926  O OD1 . ASP C 1 343 ? 40.290  -21.284 -8.918  1.00 48.08  ? 343 ASP C OD1 1 
ATOM   9927  O OD2 . ASP C 1 343 ? 39.087  -22.695 -7.782  1.00 62.70  ? 343 ASP C OD2 1 
ATOM   9928  N N   . ASP C 1 344 ? 35.933  -18.339 -9.688  1.00 36.10  ? 344 ASP C N   1 
ATOM   9929  C CA  . ASP C 1 344 ? 34.737  -17.887 -10.370 1.00 33.53  ? 344 ASP C CA  1 
ATOM   9930  C C   . ASP C 1 344 ? 35.124  -17.043 -11.576 1.00 28.90  ? 344 ASP C C   1 
ATOM   9931  O O   . ASP C 1 344 ? 35.844  -16.048 -11.476 1.00 33.46  ? 344 ASP C O   1 
ATOM   9932  C CB  . ASP C 1 344 ? 33.811  -17.196 -9.374  1.00 37.96  ? 344 ASP C CB  1 
ATOM   9933  C CG  . ASP C 1 344 ? 32.561  -16.602 -9.992  1.00 43.36  ? 344 ASP C CG  1 
ATOM   9934  O OD1 . ASP C 1 344 ? 32.696  -15.553 -10.677 1.00 40.75  ? 344 ASP C OD1 1 
ATOM   9935  O OD2 . ASP C 1 344 ? 31.466  -17.188 -9.764  1.00 47.63  ? 344 ASP C OD2 1 
ATOM   9936  N N   . GLU C 1 345 ? 34.577  -17.435 -12.723 1.00 30.76  ? 345 GLU C N   1 
ATOM   9937  C CA  . GLU C 1 345 ? 34.960  -16.853 -13.998 1.00 36.62  ? 345 GLU C CA  1 
ATOM   9938  C C   . GLU C 1 345 ? 34.583  -15.383 -14.045 1.00 34.37  ? 345 GLU C C   1 
ATOM   9939  O O   . GLU C 1 345 ? 35.348  -14.570 -14.555 1.00 35.35  ? 345 GLU C O   1 
ATOM   9940  C CB  . GLU C 1 345 ? 34.257  -17.550 -15.158 1.00 44.53  ? 345 GLU C CB  1 
ATOM   9941  C CG  . GLU C 1 345 ? 34.646  -19.009 -15.328 1.00 55.36  ? 345 GLU C CG  1 
ATOM   9942  C CD  . GLU C 1 345 ? 35.849  -19.230 -16.224 1.00 63.71  ? 345 GLU C CD  1 
ATOM   9943  O OE1 . GLU C 1 345 ? 36.938  -19.521 -15.686 1.00 77.01  ? 345 GLU C OE1 1 
ATOM   9944  O OE2 . GLU C 1 345 ? 35.687  -19.140 -17.458 1.00 70.72  ? 345 GLU C OE2 1 
ATOM   9945  N N   . LEU C 1 346 ? 33.415  -15.026 -13.508 1.00 32.96  ? 346 LEU C N   1 
ATOM   9946  C CA  . LEU C 1 346 ? 33.041  -13.616 -13.523 1.00 33.79  ? 346 LEU C CA  1 
ATOM   9947  C C   . LEU C 1 346 ? 33.958  -12.820 -12.592 1.00 28.47  ? 346 LEU C C   1 
ATOM   9948  O O   . LEU C 1 346 ? 34.350  -11.707 -12.926 1.00 28.07  ? 346 LEU C O   1 
ATOM   9949  C CB  . LEU C 1 346 ? 31.576  -13.433 -13.149 1.00 30.91  ? 346 LEU C CB  1 
ATOM   9950  C CG  . LEU C 1 346 ? 30.582  -14.152 -14.041 1.00 32.22  ? 346 LEU C CG  1 
ATOM   9951  C CD1 . LEU C 1 346 ? 29.171  -13.786 -13.635 1.00 34.51  ? 346 LEU C CD1 1 
ATOM   9952  C CD2 . LEU C 1 346 ? 30.815  -13.839 -15.501 1.00 33.57  ? 346 LEU C CD2 1 
ATOM   9953  N N   . PHE C 1 347 ? 34.321  -13.395 -11.454 1.00 29.58  ? 347 PHE C N   1 
ATOM   9954  C CA  . PHE C 1 347 ? 35.291  -12.735 -10.589 1.00 31.45  ? 347 PHE C CA  1 
ATOM   9955  C C   . PHE C 1 347 ? 36.640  -12.563 -11.312 1.00 33.37  ? 347 PHE C C   1 
ATOM   9956  O O   . PHE C 1 347 ? 37.281  -11.520 -11.210 1.00 32.37  ? 347 PHE C O   1 
ATOM   9957  C CB  . PHE C 1 347 ? 35.440  -13.490 -9.266  1.00 31.17  ? 347 PHE C CB  1 
ATOM   9958  C CG  . PHE C 1 347 ? 36.625  -13.017 -8.469  1.00 31.39  ? 347 PHE C CG  1 
ATOM   9959  C CD1 . PHE C 1 347 ? 36.751  -11.686 -8.128  1.00 30.32  ? 347 PHE C CD1 1 
ATOM   9960  C CD2 . PHE C 1 347 ? 37.696  -13.860 -8.227  1.00 35.73  ? 347 PHE C CD2 1 
ATOM   9961  C CE1 . PHE C 1 347 ? 37.843  -11.230 -7.411  1.00 32.30  ? 347 PHE C CE1 1 
ATOM   9962  C CE2 . PHE C 1 347 ? 38.807  -13.396 -7.546  1.00 38.45  ? 347 PHE C CE2 1 
ATOM   9963  C CZ  . PHE C 1 347 ? 38.869  -12.085 -7.119  1.00 33.65  ? 347 PHE C CZ  1 
ATOM   9964  N N   . LYS C 1 348 ? 37.062  -13.552 -12.096 1.00 34.60  ? 348 LYS C N   1 
ATOM   9965  C CA  . LYS C 1 348 ? 38.311  -13.395 -12.829 1.00 36.28  ? 348 LYS C CA  1 
ATOM   9966  C C   . LYS C 1 348 ? 38.251  -12.184 -13.744 1.00 34.59  ? 348 LYS C C   1 
ATOM   9967  O O   . LYS C 1 348 ? 39.260  -11.511 -13.913 1.00 37.57  ? 348 LYS C O   1 
ATOM   9968  C CB  . LYS C 1 348 ? 38.655  -14.656 -13.617 1.00 40.78  ? 348 LYS C CB  1 
ATOM   9969  C CG  . LYS C 1 348 ? 39.067  -15.797 -12.703 1.00 48.48  ? 348 LYS C CG  1 
ATOM   9970  C CD  . LYS C 1 348 ? 39.899  -16.862 -13.355 1.00 60.39  ? 348 LYS C CD  1 
ATOM   9971  C CE  . LYS C 1 348 ? 40.645  -17.684 -12.320 1.00 69.20  ? 348 LYS C CE  1 
ATOM   9972  N NZ  . LYS C 1 348 ? 41.032  -19.006 -12.862 1.00 81.75  ? 348 LYS C NZ  1 
ATOM   9973  N N   . ILE C 1 349 ? 37.079  -11.874 -14.318 1.00 31.11  ? 349 ILE C N   1 
ATOM   9974  C CA  . ILE C 1 349 ? 36.984  -10.706 -15.172 1.00 30.85  ? 349 ILE C CA  1 
ATOM   9975  C C   . ILE C 1 349 ? 37.075  -9.437  -14.317 1.00 34.19  ? 349 ILE C C   1 
ATOM   9976  O O   . ILE C 1 349 ? 37.789  -8.509  -14.685 1.00 32.70  ? 349 ILE C O   1 
ATOM   9977  C CB  . ILE C 1 349 ? 35.726  -10.748 -16.044 1.00 30.17  ? 349 ILE C CB  1 
ATOM   9978  C CG1 . ILE C 1 349 ? 35.732  -11.993 -16.915 1.00 29.69  ? 349 ILE C CG1 1 
ATOM   9979  C CG2 . ILE C 1 349 ? 35.590  -9.477  -16.880 1.00 31.65  ? 349 ILE C CG2 1 
ATOM   9980  C CD1 . ILE C 1 349 ? 34.522  -12.109 -17.810 1.00 31.34  ? 349 ILE C CD1 1 
ATOM   9981  N N   . VAL C 1 350 ? 36.401  -9.411  -13.159 1.00 33.28  ? 350 VAL C N   1 
ATOM   9982  C CA  . VAL C 1 350 ? 36.424  -8.239  -12.288 1.00 32.84  ? 350 VAL C CA  1 
ATOM   9983  C C   . VAL C 1 350 ? 37.859  -7.928  -11.893 1.00 32.16  ? 350 VAL C C   1 
ATOM   9984  O O   . VAL C 1 350 ? 38.266  -6.764  -11.844 1.00 32.70  ? 350 VAL C O   1 
ATOM   9985  C CB  . VAL C 1 350 ? 35.553  -8.476  -11.038 1.00 34.16  ? 350 VAL C CB  1 
ATOM   9986  C CG1 . VAL C 1 350 ? 35.915  -7.548  -9.899  1.00 33.88  ? 350 VAL C CG1 1 
ATOM   9987  C CG2 . VAL C 1 350 ? 34.071  -8.377  -11.361 1.00 34.47  ? 350 VAL C CG2 1 
ATOM   9988  N N   . SER C 1 351 ? 38.583  -8.999  -11.564 1.00 33.99  ? 351 SER C N   1 
ATOM   9989  C CA  . SER C 1 351 ? 39.964  -8.945  -11.115 1.00 34.69  ? 351 SER C CA  1 
ATOM   9990  C C   . SER C 1 351 ? 40.879  -8.425  -12.238 1.00 37.89  ? 351 SER C C   1 
ATOM   9991  O O   . SER C 1 351 ? 41.751  -7.601  -12.013 1.00 37.00  ? 351 SER C O   1 
ATOM   9992  C CB  . SER C 1 351 ? 40.344  -10.313 -10.607 1.00 34.21  ? 351 SER C CB  1 
ATOM   9993  O OG  . SER C 1 351 ? 41.611  -10.288 -9.982  1.00 43.40  ? 351 SER C OG  1 
ATOM   9994  N N   . LEU C 1 352 ? 40.631  -8.843  -13.477 1.00 35.25  ? 352 LEU C N   1 
ATOM   9995  C CA  . LEU C 1 352 ? 41.379  -8.365  -14.633 1.00 37.02  ? 352 LEU C CA  1 
ATOM   9996  C C   . LEU C 1 352 ? 41.138  -6.871  -14.873 1.00 39.02  ? 352 LEU C C   1 
ATOM   9997  O O   . LEU C 1 352 ? 42.062  -6.108  -15.118 1.00 33.70  ? 352 LEU C O   1 
ATOM   9998  C CB  . LEU C 1 352 ? 40.919  -9.184  -15.841 1.00 34.68  ? 352 LEU C CB  1 
ATOM   9999  C CG  . LEU C 1 352 ? 41.828  -9.156  -17.079 1.00 48.00  ? 352 LEU C CG  1 
ATOM   10000 C CD1 . LEU C 1 352 ? 43.119  -9.941  -16.831 1.00 51.36  ? 352 LEU C CD1 1 
ATOM   10001 C CD2 . LEU C 1 352 ? 41.093  -9.731  -18.283 1.00 47.71  ? 352 LEU C CD2 1 
ATOM   10002 N N   . CYS C 1 353 ? 39.876  -6.441  -14.835 1.00 38.55  ? 353 CYS C N   1 
ATOM   10003 C CA  . CYS C 1 353 ? 39.551  -5.032  -14.905 1.00 39.05  ? 353 CYS C CA  1 
ATOM   10004 C C   . CYS C 1 353 ? 40.355  -4.221  -13.887 1.00 38.00  ? 353 CYS C C   1 
ATOM   10005 O O   . CYS C 1 353 ? 40.729  -3.077  -14.160 1.00 37.40  ? 353 CYS C O   1 
ATOM   10006 C CB  . CYS C 1 353 ? 38.064  -4.800  -14.668 1.00 38.59  ? 353 CYS C CB  1 
ATOM   10007 S SG  . CYS C 1 353 ? 37.018  -5.387  -16.018 1.00 38.44  ? 353 CYS C SG  1 
ATOM   10008 N N   . TYR C 1 354 ? 40.562  -4.778  -12.694 1.00 35.30  ? 354 TYR C N   1 
ATOM   10009 C CA  . TYR C 1 354 ? 41.296  -4.053  -11.664 1.00 37.52  ? 354 TYR C CA  1 
ATOM   10010 C C   . TYR C 1 354 ? 42.737  -3.779  -12.132 1.00 40.90  ? 354 TYR C C   1 
ATOM   10011 O O   . TYR C 1 354 ? 43.306  -2.759  -11.779 1.00 35.97  ? 354 TYR C O   1 
ATOM   10012 C CB  . TYR C 1 354 ? 41.323  -4.860  -10.367 1.00 37.94  ? 354 TYR C CB  1 
ATOM   10013 C CG  . TYR C 1 354 ? 41.817  -4.146  -9.130  1.00 36.78  ? 354 TYR C CG  1 
ATOM   10014 C CD1 . TYR C 1 354 ? 41.719  -2.780  -8.983  1.00 37.42  ? 354 TYR C CD1 1 
ATOM   10015 C CD2 . TYR C 1 354 ? 42.354  -4.873  -8.083  1.00 38.41  ? 354 TYR C CD2 1 
ATOM   10016 C CE1 . TYR C 1 354 ? 42.145  -2.148  -7.825  1.00 38.82  ? 354 TYR C CE1 1 
ATOM   10017 C CE2 . TYR C 1 354 ? 42.759  -4.266  -6.909  1.00 40.25  ? 354 TYR C CE2 1 
ATOM   10018 C CZ  . TYR C 1 354 ? 42.650  -2.896  -6.780  1.00 38.94  ? 354 TYR C CZ  1 
ATOM   10019 O OH  . TYR C 1 354 ? 43.034  -2.298  -5.610  1.00 42.41  ? 354 TYR C OH  1 
ATOM   10020 N N   . GLU C 1 355 ? 43.334  -4.702  -12.902 1.00 45.61  ? 355 GLU C N   1 
ATOM   10021 C CA  . GLU C 1 355 ? 44.686  -4.525  -13.435 1.00 49.41  ? 355 GLU C CA  1 
ATOM   10022 C C   . GLU C 1 355 ? 44.707  -3.575  -14.626 1.00 45.18  ? 355 GLU C C   1 
ATOM   10023 O O   . GLU C 1 355 ? 45.626  -2.780  -14.729 1.00 49.40  ? 355 GLU C O   1 
ATOM   10024 C CB  . GLU C 1 355 ? 45.283  -5.839  -13.935 1.00 51.99  ? 355 GLU C CB  1 
ATOM   10025 C CG  . GLU C 1 355 ? 45.516  -6.871  -12.849 1.00 59.57  ? 355 GLU C CG  1 
ATOM   10026 C CD  . GLU C 1 355 ? 45.719  -8.284  -13.376 1.00 66.65  ? 355 GLU C CD  1 
ATOM   10027 O OE1 . GLU C 1 355 ? 45.615  -9.226  -12.571 1.00 78.12  ? 355 GLU C OE1 1 
ATOM   10028 O OE2 . GLU C 1 355 ? 45.963  -8.446  -14.594 1.00 77.63  ? 355 GLU C OE2 1 
ATOM   10029 N N   . VAL C 1 356 ? 43.689  -3.659  -15.502 1.00 44.14  ? 356 VAL C N   1 
ATOM   10030 C CA  . VAL C 1 356 ? 43.693  -3.036  -16.821 1.00 43.00  ? 356 VAL C CA  1 
ATOM   10031 C C   . VAL C 1 356 ? 43.014  -1.670  -16.836 1.00 45.45  ? 356 VAL C C   1 
ATOM   10032 O O   . VAL C 1 356 ? 43.538  -0.745  -17.463 1.00 44.43  ? 356 VAL C O   1 
ATOM   10033 C CB  . VAL C 1 356 ? 43.023  -3.946  -17.868 1.00 37.54  ? 356 VAL C CB  1 
ATOM   10034 C CG1 . VAL C 1 356 ? 42.832  -3.226  -19.188 1.00 38.41  ? 356 VAL C CG1 1 
ATOM   10035 C CG2 . VAL C 1 356 ? 43.810  -5.232  -18.062 1.00 36.70  ? 356 VAL C CG2 1 
ATOM   10036 N N   . ILE C 1 357 ? 41.810  -1.552  -16.244 1.00 40.26  ? 357 ILE C N   1 
ATOM   10037 C CA  . ILE C 1 357 ? 40.972  -0.402  -16.533 1.00 36.57  ? 357 ILE C CA  1 
ATOM   10038 C C   . ILE C 1 357 ? 41.570  0.879   -15.948 1.00 38.58  ? 357 ILE C C   1 
ATOM   10039 O O   . ILE C 1 357 ? 41.437  1.947   -16.548 1.00 37.02  ? 357 ILE C O   1 
ATOM   10040 C CB  . ILE C 1 357 ? 39.523  -0.615  -16.061 1.00 38.76  ? 357 ILE C CB  1 
ATOM   10041 C CG1 . ILE C 1 357 ? 38.799  -1.715  -16.853 1.00 36.54  ? 357 ILE C CG1 1 
ATOM   10042 C CG2 . ILE C 1 357 ? 38.771  0.700   -16.058 1.00 35.73  ? 357 ILE C CG2 1 
ATOM   10043 C CD1 . ILE C 1 357 ? 38.695  -1.455  -18.321 1.00 43.87  ? 357 ILE C CD1 1 
ATOM   10044 N N   . PRO C 1 358 ? 42.179  0.892   -14.748 1.00 42.08  ? 358 PRO C N   1 
ATOM   10045 C CA  . PRO C 1 358 ? 42.669  2.165   -14.209 1.00 44.66  ? 358 PRO C CA  1 
ATOM   10046 C C   . PRO C 1 358 ? 43.689  2.823   -15.151 1.00 48.95  ? 358 PRO C C   1 
ATOM   10047 O O   . PRO C 1 358 ? 43.552  4.003   -15.469 1.00 45.43  ? 358 PRO C O   1 
ATOM   10048 C CB  . PRO C 1 358 ? 43.255  1.784   -12.846 1.00 45.02  ? 358 PRO C CB  1 
ATOM   10049 C CG  . PRO C 1 358 ? 42.578  0.461   -12.501 1.00 47.86  ? 358 PRO C CG  1 
ATOM   10050 C CD  . PRO C 1 358 ? 42.420  -0.240  -13.839 1.00 43.95  ? 358 PRO C CD  1 
ATOM   10051 N N   . GLU C 1 359 ? 44.656  2.049   -15.663 1.00 50.99  ? 359 GLU C N   1 
ATOM   10052 C CA  . GLU C 1 359 ? 45.603  2.573   -16.649 1.00 56.96  ? 359 GLU C CA  1 
ATOM   10053 C C   . GLU C 1 359 ? 44.864  3.268   -17.795 1.00 49.98  ? 359 GLU C C   1 
ATOM   10054 O O   . GLU C 1 359 ? 45.249  4.350   -18.219 1.00 42.48  ? 359 GLU C O   1 
ATOM   10055 C CB  . GLU C 1 359 ? 46.410  1.494   -17.369 1.00 60.11  ? 359 GLU C CB  1 
ATOM   10056 C CG  . GLU C 1 359 ? 47.124  0.490   -16.488 1.00 75.23  ? 359 GLU C CG  1 
ATOM   10057 C CD  . GLU C 1 359 ? 47.441  -0.799  -17.238 1.00 85.02  ? 359 GLU C CD  1 
ATOM   10058 O OE1 . GLU C 1 359 ? 46.793  -1.060  -18.294 1.00 88.25  ? 359 GLU C OE1 1 
ATOM   10059 O OE2 . GLU C 1 359 ? 48.338  -1.538  -16.781 1.00 88.95  ? 359 GLU C OE2 1 
ATOM   10060 N N   . VAL C 1 360 ? 43.810  2.630   -18.314 1.00 40.34  ? 360 VAL C N   1 
ATOM   10061 C CA  . VAL C 1 360 ? 43.128  3.125   -19.495 1.00 38.15  ? 360 VAL C CA  1 
ATOM   10062 C C   . VAL C 1 360 ? 42.418  4.433   -19.171 1.00 42.34  ? 360 VAL C C   1 
ATOM   10063 O O   . VAL C 1 360 ? 42.462  5.385   -19.958 1.00 42.46  ? 360 VAL C O   1 
ATOM   10064 C CB  . VAL C 1 360 ? 42.186  2.057   -20.068 1.00 37.46  ? 360 VAL C CB  1 
ATOM   10065 C CG1 . VAL C 1 360 ? 41.187  2.591   -21.089 1.00 39.01  ? 360 VAL C CG1 1 
ATOM   10066 C CG2 . VAL C 1 360 ? 43.001  0.912   -20.654 1.00 42.86  ? 360 VAL C CG2 1 
ATOM   10067 N N   . LEU C 1 361 ? 41.800  4.508   -17.986 1.00 44.17  ? 361 LEU C N   1 
ATOM   10068 C CA  . LEU C 1 361 ? 41.025  5.688   -17.652 1.00 40.46  ? 361 LEU C CA  1 
ATOM   10069 C C   . LEU C 1 361 ? 41.959  6.878   -17.392 1.00 38.26  ? 361 LEU C C   1 
ATOM   10070 O O   . LEU C 1 361 ? 41.581  7.997   -17.711 1.00 39.34  ? 361 LEU C O   1 
ATOM   10071 C CB  . LEU C 1 361 ? 40.121  5.377   -16.451 1.00 42.72  ? 361 LEU C CB  1 
ATOM   10072 C CG  . LEU C 1 361 ? 38.877  4.533   -16.747 1.00 42.50  ? 361 LEU C CG  1 
ATOM   10073 C CD1 . LEU C 1 361 ? 38.139  4.234   -15.457 1.00 45.20  ? 361 LEU C CD1 1 
ATOM   10074 C CD2 . LEU C 1 361 ? 37.912  5.188   -17.744 1.00 39.83  ? 361 LEU C CD2 1 
ATOM   10075 N N   . LYS C 1 362 ? 43.163  6.632   -16.839 1.00 45.50  ? 362 LYS C N   1 
ATOM   10076 C CA  . LYS C 1 362 ? 44.160  7.677   -16.655 1.00 52.52  ? 362 LYS C CA  1 
ATOM   10077 C C   . LYS C 1 362 ? 44.521  8.302   -18.009 1.00 58.48  ? 362 LYS C C   1 
ATOM   10078 O O   . LYS C 1 362 ? 44.364  9.511   -18.177 1.00 56.53  ? 362 LYS C O   1 
ATOM   10079 C CB  . LYS C 1 362 ? 45.438  7.143   -16.011 1.00 55.34  ? 362 LYS C CB  1 
ATOM   10080 C CG  . LYS C 1 362 ? 45.355  6.774   -14.546 1.00 67.78  ? 362 LYS C CG  1 
ATOM   10081 C CD  . LYS C 1 362 ? 46.671  6.230   -14.017 1.00 75.84  ? 362 LYS C CD  1 
ATOM   10082 C CE  . LYS C 1 362 ? 46.507  5.411   -12.754 1.00 80.36  ? 362 LYS C CE  1 
ATOM   10083 N NZ  . LYS C 1 362 ? 47.813  5.092   -12.133 1.00 85.03  ? 362 LYS C NZ  1 
ATOM   10084 N N   . LYS C 1 363 ? 44.940  7.463   -18.975 1.00 56.85  ? 363 LYS C N   1 
ATOM   10085 C CA  . LYS C 1 363 ? 45.342  7.905   -20.305 1.00 51.82  ? 363 LYS C CA  1 
ATOM   10086 C C   . LYS C 1 363 ? 44.186  8.581   -21.020 1.00 47.61  ? 363 LYS C C   1 
ATOM   10087 O O   . LYS C 1 363 ? 44.367  9.630   -21.621 1.00 57.64  ? 363 LYS C O   1 
ATOM   10088 C CB  . LYS C 1 363 ? 45.886  6.739   -21.134 1.00 56.02  ? 363 LYS C CB  1 
ATOM   10089 C CG  . LYS C 1 363 ? 47.185  6.159   -20.584 1.00 73.62  ? 363 LYS C CG  1 
ATOM   10090 C CD  . LYS C 1 363 ? 47.569  4.765   -21.092 1.00 85.88  ? 363 LYS C CD  1 
ATOM   10091 C CE  . LYS C 1 363 ? 48.550  4.060   -20.167 1.00 89.88  ? 363 LYS C CE  1 
ATOM   10092 N NZ  . LYS C 1 363 ? 49.171  2.863   -20.791 1.00 81.27  ? 363 LYS C NZ  1 
ATOM   10093 N N   . HIS C 1 364 ? 42.992  8.000   -20.953 1.00 50.46  ? 364 HIS C N   1 
ATOM   10094 C CA  . HIS C 1 364 ? 41.834  8.593   -21.604 1.00 49.66  ? 364 HIS C CA  1 
ATOM   10095 C C   . HIS C 1 364 ? 41.615  10.004  -21.065 1.00 49.84  ? 364 HIS C C   1 
ATOM   10096 O O   . HIS C 1 364 ? 41.203  10.878  -21.806 1.00 47.33  ? 364 HIS C O   1 
ATOM   10097 C CB  . HIS C 1 364 ? 40.603  7.731   -21.342 1.00 49.55  ? 364 HIS C CB  1 
ATOM   10098 C CG  . HIS C 1 364 ? 39.346  8.258   -21.911 1.00 46.81  ? 364 HIS C CG  1 
ATOM   10099 N ND1 . HIS C 1 364 ? 38.286  8.678   -21.130 1.00 50.69  ? 364 HIS C ND1 1 
ATOM   10100 C CD2 . HIS C 1 364 ? 38.964  8.381   -23.184 1.00 45.54  ? 364 HIS C CD2 1 
ATOM   10101 C CE1 . HIS C 1 364 ? 37.294  9.053   -21.922 1.00 49.69  ? 364 HIS C CE1 1 
ATOM   10102 N NE2 . HIS C 1 364 ? 37.696  8.887   -23.180 1.00 47.59  ? 364 HIS C NE2 1 
ATOM   10103 N N   . GLY C 1 365 ? 41.830  10.181  -19.752 1.00 46.76  ? 365 GLY C N   1 
ATOM   10104 C CA  . GLY C 1 365 ? 42.065  11.488  -19.152 1.00 54.13  ? 365 GLY C CA  1 
ATOM   10105 C C   . GLY C 1 365 ? 40.822  12.282  -18.745 1.00 51.96  ? 365 GLY C C   1 
ATOM   10106 O O   . GLY C 1 365 ? 40.963  13.426  -18.343 1.00 57.85  ? 365 GLY C O   1 
ATOM   10107 N N   . LYS C 1 366 ? 39.616  11.707  -18.805 1.00 49.48  ? 366 LYS C N   1 
ATOM   10108 C CA  . LYS C 1 366 ? 38.424  12.469  -18.457 1.00 51.43  ? 366 LYS C CA  1 
ATOM   10109 C C   . LYS C 1 366 ? 38.050  12.264  -16.988 1.00 47.81  ? 366 LYS C C   1 
ATOM   10110 O O   . LYS C 1 366 ? 37.815  13.235  -16.286 1.00 46.92  ? 366 LYS C O   1 
ATOM   10111 C CB  . LYS C 1 366 ? 37.282  12.131  -19.408 1.00 54.97  ? 366 LYS C CB  1 
ATOM   10112 C CG  . LYS C 1 366 ? 37.514  12.617  -20.830 1.00 57.55  ? 366 LYS C CG  1 
ATOM   10113 C CD  . LYS C 1 366 ? 36.245  12.763  -21.641 1.00 65.13  ? 366 LYS C CD  1 
ATOM   10114 C CE  . LYS C 1 366 ? 36.505  13.413  -22.984 1.00 68.60  ? 366 LYS C CE  1 
ATOM   10115 N NZ  . LYS C 1 366 ? 35.276  14.037  -23.525 1.00 81.34  ? 366 LYS C NZ  1 
ATOM   10116 N N   . ALA C 1 367 ? 38.060  11.012  -16.516 1.00 51.10  ? 367 ALA C N   1 
ATOM   10117 C CA  . ALA C 1 367 ? 37.657  10.677  -15.159 1.00 50.38  ? 367 ALA C CA  1 
ATOM   10118 C C   . ALA C 1 367 ? 38.641  11.248  -14.142 1.00 51.39  ? 367 ALA C C   1 
ATOM   10119 O O   . ALA C 1 367 ? 39.847  10.997  -14.197 1.00 45.21  ? 367 ALA C O   1 
ATOM   10120 C CB  . ALA C 1 367 ? 37.548  9.181   -14.990 1.00 46.08  ? 367 ALA C CB  1 
ATOM   10121 N N   . LYS C 1 368 ? 38.081  11.958  -13.163 1.00 51.00  ? 368 LYS C N   1 
ATOM   10122 C CA  . LYS C 1 368 ? 38.838  12.443  -12.017 1.00 46.22  ? 368 LYS C CA  1 
ATOM   10123 C C   . LYS C 1 368 ? 39.360  11.264  -11.200 1.00 50.60  ? 368 LYS C C   1 
ATOM   10124 O O   . LYS C 1 368 ? 40.380  11.366  -10.525 1.00 54.29  ? 368 LYS C O   1 
ATOM   10125 C CB  . LYS C 1 368 ? 37.927  13.383  -11.213 1.00 47.93  ? 368 LYS C CB  1 
ATOM   10126 N N   . ASN C 1 369 ? 38.652  10.131  -11.267 1.00 47.09  ? 369 ASN C N   1 
ATOM   10127 C CA  . ASN C 1 369 ? 38.970  8.964   -10.468 1.00 47.37  ? 369 ASN C CA  1 
ATOM   10128 C C   . ASN C 1 369 ? 38.945  7.730   -11.365 1.00 45.13  ? 369 ASN C C   1 
ATOM   10129 O O   . ASN C 1 369 ? 37.866  7.285   -11.772 1.00 48.82  ? 369 ASN C O   1 
ATOM   10130 C CB  . ASN C 1 369 ? 37.990  8.770   -9.309  1.00 47.45  ? 369 ASN C CB  1 
ATOM   10131 C CG  . ASN C 1 369 ? 38.318  7.547   -8.482  1.00 45.63  ? 369 ASN C CG  1 
ATOM   10132 O OD1 . ASN C 1 369 ? 39.465  7.113   -8.441  1.00 44.34  ? 369 ASN C OD1 1 
ATOM   10133 N ND2 . ASN C 1 369 ? 37.318  6.980   -7.820  1.00 52.68  ? 369 ASN C ND2 1 
ATOM   10134 N N   . PRO C 1 370 ? 40.130  7.159   -11.688 1.00 43.98  ? 370 PRO C N   1 
ATOM   10135 C CA  . PRO C 1 370 ? 40.237  6.005   -12.586 1.00 43.89  ? 370 PRO C CA  1 
ATOM   10136 C C   . PRO C 1 370 ? 40.154  4.644   -11.893 1.00 41.67  ? 370 PRO C C   1 
ATOM   10137 O O   . PRO C 1 370 ? 40.281  3.602   -12.524 1.00 43.75  ? 370 PRO C O   1 
ATOM   10138 C CB  . PRO C 1 370 ? 41.653  6.207   -13.148 1.00 42.86  ? 370 PRO C CB  1 
ATOM   10139 C CG  . PRO C 1 370 ? 42.439  6.762   -11.973 1.00 45.32  ? 370 PRO C CG  1 
ATOM   10140 C CD  . PRO C 1 370 ? 41.450  7.631   -11.227 1.00 46.69  ? 370 PRO C CD  1 
ATOM   10141 N N   . TRP C 1 371 ? 39.932  4.669   -10.576 1.00 41.36  ? 371 TRP C N   1 
ATOM   10142 C CA  . TRP C 1 371 ? 39.925  3.479   -9.739  1.00 40.47  ? 371 TRP C CA  1 
ATOM   10143 C C   . TRP C 1 371 ? 38.491  2.989   -9.517  1.00 36.09  ? 371 TRP C C   1 
ATOM   10144 O O   . TRP C 1 371 ? 37.515  3.728   -9.700  1.00 34.71  ? 371 TRP C O   1 
ATOM   10145 C CB  . TRP C 1 371 ? 40.645  3.790   -8.423  1.00 41.73  ? 371 TRP C CB  1 
ATOM   10146 C CG  . TRP C 1 371 ? 42.063  4.203   -8.632  1.00 47.48  ? 371 TRP C CG  1 
ATOM   10147 C CD1 . TRP C 1 371 ? 42.575  5.469   -8.568  1.00 56.48  ? 371 TRP C CD1 1 
ATOM   10148 C CD2 . TRP C 1 371 ? 43.164  3.336   -8.945  1.00 52.18  ? 371 TRP C CD2 1 
ATOM   10149 N NE1 . TRP C 1 371 ? 43.922  5.454   -8.813  1.00 48.31  ? 371 TRP C NE1 1 
ATOM   10150 C CE2 . TRP C 1 371 ? 44.310  4.159   -9.059  1.00 58.36  ? 371 TRP C CE2 1 
ATOM   10151 C CE3 . TRP C 1 371 ? 43.291  1.958   -9.141  1.00 53.01  ? 371 TRP C CE3 1 
ATOM   10152 C CZ2 . TRP C 1 371 ? 45.559  3.640   -9.385  1.00 45.97  ? 371 TRP C CZ2 1 
ATOM   10153 C CZ3 . TRP C 1 371 ? 44.533  1.445   -9.443  1.00 58.05  ? 371 TRP C CZ3 1 
ATOM   10154 C CH2 . TRP C 1 371 ? 45.650  2.276   -9.550  1.00 50.92  ? 371 TRP C CH2 1 
ATOM   10155 N N   . PRO C 1 372 ? 38.319  1.724   -9.099  1.00 33.08  ? 372 PRO C N   1 
ATOM   10156 C CA  . PRO C 1 372 ? 36.987  1.183   -8.879  1.00 38.36  ? 372 PRO C CA  1 
ATOM   10157 C C   . PRO C 1 372 ? 36.351  1.619   -7.562  1.00 34.12  ? 372 PRO C C   1 
ATOM   10158 O O   . PRO C 1 372 ? 37.026  1.941   -6.571  1.00 34.13  ? 372 PRO C O   1 
ATOM   10159 C CB  . PRO C 1 372 ? 37.201  -0.330  -8.915  1.00 34.34  ? 372 PRO C CB  1 
ATOM   10160 C CG  . PRO C 1 372 ? 38.623  -0.517  -8.466  1.00 38.47  ? 372 PRO C CG  1 
ATOM   10161 C CD  . PRO C 1 372 ? 39.365  0.717   -8.922  1.00 37.75  ? 372 PRO C CD  1 
ATOM   10162 N N   . ASN C 1 373 ? 35.025  1.629   -7.616  1.00 35.77  ? 373 ASN C N   1 
ATOM   10163 C CA  . ASN C 1 373 ? 34.159  1.891   -6.483  1.00 34.60  ? 373 ASN C CA  1 
ATOM   10164 C C   . ASN C 1 373 ? 33.529  0.573   -6.018  1.00 37.72  ? 373 ASN C C   1 
ATOM   10165 O O   . ASN C 1 373 ? 33.698  -0.476  -6.650  1.00 34.79  ? 373 ASN C O   1 
ATOM   10166 C CB  . ASN C 1 373 ? 33.124  2.954   -6.845  1.00 36.55  ? 373 ASN C CB  1 
ATOM   10167 C CG  . ASN C 1 373 ? 32.210  2.557   -7.983  1.00 41.16  ? 373 ASN C CG  1 
ATOM   10168 O OD1 . ASN C 1 373 ? 31.544  1.519   -7.916  1.00 39.95  ? 373 ASN C OD1 1 
ATOM   10169 N ND2 . ASN C 1 373 ? 32.174  3.374   -9.027  1.00 37.09  ? 373 ASN C ND2 1 
ATOM   10170 N N   . VAL C 1 374 ? 32.794  0.655   -4.904  1.00 31.81  ? 374 VAL C N   1 
ATOM   10171 C CA  . VAL C 1 374 ? 32.151  -0.478  -4.245  1.00 31.12  ? 374 VAL C CA  1 
ATOM   10172 C C   . VAL C 1 374 ? 31.331  -1.297  -5.246  1.00 31.81  ? 374 VAL C C   1 
ATOM   10173 O O   . VAL C 1 374 ? 31.339  -2.530  -5.192  1.00 29.63  ? 374 VAL C O   1 
ATOM   10174 C CB  . VAL C 1 374 ? 31.296  0.037   -3.059  1.00 30.66  ? 374 VAL C CB  1 
ATOM   10175 C CG1 . VAL C 1 374 ? 30.150  0.940   -3.509  1.00 35.67  ? 374 VAL C CG1 1 
ATOM   10176 C CG2 . VAL C 1 374 ? 30.763  -1.077  -2.199  1.00 34.72  ? 374 VAL C CG2 1 
ATOM   10177 N N   . ASP C 1 375 ? 30.649  -0.610  -6.173  1.00 29.64  ? 375 ASP C N   1 
ATOM   10178 C CA  . ASP C 1 375 ? 29.704  -1.266  -7.070  1.00 32.97  ? 375 ASP C CA  1 
ATOM   10179 C C   . ASP C 1 375 ? 30.377  -2.115  -8.147  1.00 31.95  ? 375 ASP C C   1 
ATOM   10180 O O   . ASP C 1 375 ? 29.709  -2.897  -8.825  1.00 27.53  ? 375 ASP C O   1 
ATOM   10181 C CB  . ASP C 1 375 ? 28.807  -0.244  -7.766  1.00 34.68  ? 375 ASP C CB  1 
ATOM   10182 C CG  . ASP C 1 375 ? 27.896  0.488   -6.781  1.00 49.11  ? 375 ASP C CG  1 
ATOM   10183 O OD1 . ASP C 1 375 ? 27.304  -0.190  -5.876  1.00 44.21  ? 375 ASP C OD1 1 
ATOM   10184 O OD2 . ASP C 1 375 ? 27.761  1.730   -6.936  1.00 57.97  ? 375 ASP C OD2 1 
ATOM   10185 N N   . ALA C 1 376 ? 31.686  -1.953  -8.330  1.00 30.72  ? 376 ALA C N   1 
ATOM   10186 C CA  . ALA C 1 376 ? 32.405  -2.769  -9.295  1.00 31.31  ? 376 ALA C CA  1 
ATOM   10187 C C   . ALA C 1 376 ? 32.469  -4.235  -8.865  1.00 31.64  ? 376 ALA C C   1 
ATOM   10188 O O   . ALA C 1 376 ? 32.731  -5.102  -9.685  1.00 30.00  ? 376 ALA C O   1 
ATOM   10189 C CB  . ALA C 1 376 ? 33.788  -2.208  -9.489  1.00 30.14  ? 376 ALA C CB  1 
ATOM   10190 N N   . HIS C 1 377 ? 32.254  -4.524  -7.574  1.00 30.67  ? 377 HIS C N   1 
ATOM   10191 C CA  . HIS C 1 377 ? 32.573  -5.832  -7.032  1.00 28.64  ? 377 HIS C CA  1 
ATOM   10192 C C   . HIS C 1 377 ? 31.382  -6.598  -6.434  1.00 30.17  ? 377 HIS C C   1 
ATOM   10193 O O   . HIS C 1 377 ? 31.491  -7.797  -6.236  1.00 31.45  ? 377 HIS C O   1 
ATOM   10194 C CB  . HIS C 1 377 ? 33.657  -5.699  -5.963  1.00 29.93  ? 377 HIS C CB  1 
ATOM   10195 C CG  . HIS C 1 377 ? 34.623  -6.842  -6.012  1.00 32.97  ? 377 HIS C CG  1 
ATOM   10196 N ND1 . HIS C 1 377 ? 34.196  -8.149  -6.077  1.00 27.75  ? 377 HIS C ND1 1 
ATOM   10197 C CD2 . HIS C 1 377 ? 35.969  -6.869  -6.081  1.00 33.31  ? 377 HIS C CD2 1 
ATOM   10198 C CE1 . HIS C 1 377 ? 35.268  -8.941  -6.139  1.00 35.10  ? 377 HIS C CE1 1 
ATOM   10199 N NE2 . HIS C 1 377 ? 36.360  -8.174  -6.141  1.00 32.33  ? 377 HIS C NE2 1 
ATOM   10200 N N   . SER C 1 378 ? 30.250  -5.946  -6.128  1.00 27.04  ? 378 SER C N   1 
ATOM   10201 C CA  . SER C 1 378 ? 29.262  -6.583  -5.273  1.00 26.21  ? 378 SER C CA  1 
ATOM   10202 C C   . SER C 1 378 ? 28.436  -7.592  -6.055  1.00 27.72  ? 378 SER C C   1 
ATOM   10203 O O   . SER C 1 378 ? 28.096  -8.649  -5.519  1.00 27.97  ? 378 SER C O   1 
ATOM   10204 C CB  . SER C 1 378 ? 28.385  -5.515  -4.606  1.00 30.48  ? 378 SER C CB  1 
ATOM   10205 O OG  . SER C 1 378 ? 28.038  -4.500  -5.536  1.00 34.33  ? 378 SER C OG  1 
ATOM   10206 N N   . GLY C 1 379 ? 28.130  -7.262  -7.318  1.00 26.02  ? 379 GLY C N   1 
ATOM   10207 C CA  . GLY C 1 379 ? 27.275  -8.101  -8.147  1.00 30.28  ? 379 GLY C CA  1 
ATOM   10208 C C   . GLY C 1 379 ? 27.803  -9.517  -8.372  1.00 30.40  ? 379 GLY C C   1 
ATOM   10209 O O   . GLY C 1 379 ? 27.042  -10.489 -8.358  1.00 29.53  ? 379 GLY C O   1 
ATOM   10210 N N   . VAL C 1 380 ? 29.097  -9.652  -8.669  1.00 28.77  ? 380 VAL C N   1 
ATOM   10211 C CA  . VAL C 1 380 ? 29.640  -10.978 -8.913  1.00 28.37  ? 380 VAL C CA  1 
ATOM   10212 C C   . VAL C 1 380 ? 29.559  -11.822 -7.652  1.00 29.77  ? 380 VAL C C   1 
ATOM   10213 O O   . VAL C 1 380 ? 29.431  -13.032 -7.759  1.00 28.42  ? 380 VAL C O   1 
ATOM   10214 C CB  . VAL C 1 380 ? 31.080  -10.985 -9.462  1.00 30.52  ? 380 VAL C CB  1 
ATOM   10215 C CG1 . VAL C 1 380 ? 31.168  -10.320 -10.818 1.00 30.02  ? 380 VAL C CG1 1 
ATOM   10216 C CG2 . VAL C 1 380 ? 32.085  -10.390 -8.497  1.00 36.09  ? 380 VAL C CG2 1 
ATOM   10217 N N   . LEU C 1 381 ? 29.700  -11.211 -6.467  1.00 29.57  ? 381 LEU C N   1 
ATOM   10218 C CA  . LEU C 1 381 ? 29.558  -11.948 -5.224  1.00 28.37  ? 381 LEU C CA  1 
ATOM   10219 C C   . LEU C 1 381 ? 28.125  -12.481 -5.093  1.00 29.86  ? 381 LEU C C   1 
ATOM   10220 O O   . LEU C 1 381 ? 27.885  -13.666 -4.875  1.00 32.66  ? 381 LEU C O   1 
ATOM   10221 C CB  . LEU C 1 381 ? 29.921  -11.028 -4.054  1.00 30.65  ? 381 LEU C CB  1 
ATOM   10222 C CG  . LEU C 1 381 ? 31.369  -10.524 -3.994  1.00 29.98  ? 381 LEU C CG  1 
ATOM   10223 C CD1 . LEU C 1 381 ? 31.618  -9.732  -2.732  1.00 32.50  ? 381 LEU C CD1 1 
ATOM   10224 C CD2 . LEU C 1 381 ? 32.349  -11.665 -4.059  1.00 32.58  ? 381 LEU C CD2 1 
ATOM   10225 N N   . LEU C 1 382 ? 27.155  -11.582 -5.199  1.00 28.49  ? 382 LEU C N   1 
ATOM   10226 C CA  . LEU C 1 382 ? 25.750  -11.966 -5.098  1.00 28.99  ? 382 LEU C CA  1 
ATOM   10227 C C   . LEU C 1 382 ? 25.440  -13.073 -6.115  1.00 24.29  ? 382 LEU C C   1 
ATOM   10228 O O   . LEU C 1 382 ? 24.810  -14.074 -5.786  1.00 26.61  ? 382 LEU C O   1 
ATOM   10229 C CB  . LEU C 1 382 ? 24.903  -10.705 -5.318  1.00 27.12  ? 382 LEU C CB  1 
ATOM   10230 C CG  . LEU C 1 382 ? 25.012  -9.692  -4.176  1.00 28.40  ? 382 LEU C CG  1 
ATOM   10231 C CD1 . LEU C 1 382 ? 24.289  -8.405  -4.502  1.00 28.10  ? 382 LEU C CD1 1 
ATOM   10232 C CD2 . LEU C 1 382 ? 24.509  -10.261 -2.877  1.00 31.91  ? 382 LEU C CD2 1 
ATOM   10233 N N   . TRP C 1 383 ? 25.808  -12.859 -7.376  1.00 29.01  ? 383 TRP C N   1 
ATOM   10234 C CA  . TRP C 1 383 ? 25.481  -13.795 -8.453  1.00 30.09  ? 383 TRP C CA  1 
ATOM   10235 C C   . TRP C 1 383 ? 26.068  -15.167 -8.169  1.00 31.66  ? 383 TRP C C   1 
ATOM   10236 O O   . TRP C 1 383 ? 25.413  -16.180 -8.392  1.00 27.50  ? 383 TRP C O   1 
ATOM   10237 C CB  . TRP C 1 383 ? 25.997  -13.263 -9.797  1.00 28.93  ? 383 TRP C CB  1 
ATOM   10238 C CG  . TRP C 1 383 ? 25.607  -14.070 -10.993 1.00 27.04  ? 383 TRP C CG  1 
ATOM   10239 C CD1 . TRP C 1 383 ? 26.280  -15.130 -11.535 1.00 29.91  ? 383 TRP C CD1 1 
ATOM   10240 C CD2 . TRP C 1 383 ? 24.445  -13.879 -11.807 1.00 28.91  ? 383 TRP C CD2 1 
ATOM   10241 N NE1 . TRP C 1 383 ? 25.604  -15.631 -12.619 1.00 29.90  ? 383 TRP C NE1 1 
ATOM   10242 C CE2 . TRP C 1 383 ? 24.465  -14.897 -12.796 1.00 30.68  ? 383 TRP C CE2 1 
ATOM   10243 C CE3 . TRP C 1 383 ? 23.380  -12.972 -11.775 1.00 30.41  ? 383 TRP C CE3 1 
ATOM   10244 C CZ2 . TRP C 1 383 ? 23.487  -14.990 -13.777 1.00 33.21  ? 383 TRP C CZ2 1 
ATOM   10245 C CZ3 . TRP C 1 383 ? 22.421  -13.053 -12.766 1.00 32.40  ? 383 TRP C CZ3 1 
ATOM   10246 C CH2 . TRP C 1 383 ? 22.458  -14.073 -13.720 1.00 32.74  ? 383 TRP C CH2 1 
ATOM   10247 N N   . HIS C 1 384 ? 27.325  -15.197 -7.705  1.00 33.12  ? 384 HIS C N   1 
ATOM   10248 C CA  . HIS C 1 384 ? 28.006  -16.464 -7.423  1.00 31.72  ? 384 HIS C CA  1 
ATOM   10249 C C   . HIS C 1 384 ? 27.176  -17.306 -6.462  1.00 33.07  ? 384 HIS C C   1 
ATOM   10250 O O   . HIS C 1 384 ? 27.108  -18.519 -6.589  1.00 34.61  ? 384 HIS C O   1 
ATOM   10251 C CB  . HIS C 1 384 ? 29.370  -16.240 -6.756  1.00 34.73  ? 384 HIS C CB  1 
ATOM   10252 C CG  . HIS C 1 384 ? 30.080  -17.518 -6.388  1.00 38.16  ? 384 HIS C CG  1 
ATOM   10253 N ND1 . HIS C 1 384 ? 30.764  -18.293 -7.307  1.00 37.57  ? 384 HIS C ND1 1 
ATOM   10254 C CD2 . HIS C 1 384 ? 30.228  -18.146 -5.190  1.00 36.23  ? 384 HIS C CD2 1 
ATOM   10255 C CE1 . HIS C 1 384 ? 31.292  -19.348 -6.680  1.00 38.21  ? 384 HIS C CE1 1 
ATOM   10256 N NE2 . HIS C 1 384 ? 30.976  -19.279 -5.403  1.00 36.12  ? 384 HIS C NE2 1 
ATOM   10257 N N   . TYR C 1 385 ? 26.592  -16.682 -5.437  1.00 31.48  ? 385 TYR C N   1 
ATOM   10258 C CA  . TYR C 1 385 ? 25.872  -17.464 -4.447  1.00 30.36  ? 385 TYR C CA  1 
ATOM   10259 C C   . TYR C 1 385 ? 24.405  -17.632 -4.810  1.00 32.30  ? 385 TYR C C   1 
ATOM   10260 O O   . TYR C 1 385 ? 23.641  -18.143 -4.007  1.00 34.91  ? 385 TYR C O   1 
ATOM   10261 C CB  . TYR C 1 385 ? 26.014  -16.863 -3.054  1.00 32.02  ? 385 TYR C CB  1 
ATOM   10262 C CG  . TYR C 1 385 ? 27.377  -17.077 -2.474  1.00 31.12  ? 385 TYR C CG  1 
ATOM   10263 C CD1 . TYR C 1 385 ? 27.784  -18.318 -1.990  1.00 35.31  ? 385 TYR C CD1 1 
ATOM   10264 C CD2 . TYR C 1 385 ? 28.272  -16.039 -2.454  1.00 32.08  ? 385 TYR C CD2 1 
ATOM   10265 C CE1 . TYR C 1 385 ? 29.064  -18.498 -1.474  1.00 33.57  ? 385 TYR C CE1 1 
ATOM   10266 C CE2 . TYR C 1 385 ? 29.535  -16.197 -1.932  1.00 32.88  ? 385 TYR C CE2 1 
ATOM   10267 C CZ  . TYR C 1 385 ? 29.924  -17.421 -1.441  1.00 31.00  ? 385 TYR C CZ  1 
ATOM   10268 O OH  . TYR C 1 385 ? 31.208  -17.443 -0.997  1.00 37.65  ? 385 TYR C OH  1 
ATOM   10269 N N   . GLY C 1 386 ? 24.014  -17.285 -6.037  1.00 30.99  ? 386 GLY C N   1 
ATOM   10270 C CA  . GLY C 1 386 ? 22.658  -17.567 -6.468  1.00 31.90  ? 386 GLY C CA  1 
ATOM   10271 C C   . GLY C 1 386 ? 21.650  -16.435 -6.219  1.00 32.09  ? 386 GLY C C   1 
ATOM   10272 O O   . GLY C 1 386 ? 20.468  -16.637 -6.473  1.00 31.99  ? 386 GLY C O   1 
ATOM   10273 N N   . ILE C 1 387 ? 22.081  -15.252 -5.763  1.00 33.03  ? 387 ILE C N   1 
ATOM   10274 C CA  . ILE C 1 387 ? 21.203  -14.080 -5.768  1.00 30.11  ? 387 ILE C CA  1 
ATOM   10275 C C   . ILE C 1 387 ? 21.354  -13.385 -7.126  1.00 27.87  ? 387 ILE C C   1 
ATOM   10276 O O   . ILE C 1 387 ? 22.287  -12.620 -7.374  1.00 28.59  ? 387 ILE C O   1 
ATOM   10277 C CB  . ILE C 1 387 ? 21.441  -13.118 -4.581  1.00 31.46  ? 387 ILE C CB  1 
ATOM   10278 C CG1 . ILE C 1 387 ? 21.344  -13.791 -3.207  1.00 36.70  ? 387 ILE C CG1 1 
ATOM   10279 C CG2 . ILE C 1 387 ? 20.453  -11.963 -4.625  1.00 31.83  ? 387 ILE C CG2 1 
ATOM   10280 C CD1 . ILE C 1 387 ? 22.622  -14.390 -2.704  1.00 37.07  ? 387 ILE C CD1 1 
ATOM   10281 N N   . ARG C 1 388 ? 20.418  -13.687 -8.014  1.00 29.31  ? 388 ARG C N   1 
ATOM   10282 C CA  . ARG C 1 388 ? 20.522  -13.377 -9.421  1.00 30.87  ? 388 ARG C CA  1 
ATOM   10283 C C   . ARG C 1 388 ? 19.494  -12.368 -9.887  1.00 29.63  ? 388 ARG C C   1 
ATOM   10284 O O   . ARG C 1 388 ? 19.577  -11.943 -11.028 1.00 28.78  ? 388 ARG C O   1 
ATOM   10285 C CB  . ARG C 1 388 ? 20.364  -14.656 -10.223 1.00 34.83  ? 388 ARG C CB  1 
ATOM   10286 C CG  . ARG C 1 388 ? 21.457  -15.626 -9.846  1.00 38.62  ? 388 ARG C CG  1 
ATOM   10287 C CD  . ARG C 1 388 ? 21.701  -16.793 -10.750 1.00 45.51  ? 388 ARG C CD  1 
ATOM   10288 N NE  . ARG C 1 388 ? 23.011  -17.276 -10.281 1.00 50.00  ? 388 ARG C NE  1 
ATOM   10289 C CZ  . ARG C 1 388 ? 23.771  -18.131 -10.944 1.00 50.92  ? 388 ARG C CZ  1 
ATOM   10290 N NH1 . ARG C 1 388 ? 23.350  -18.596 -12.116 1.00 47.69  ? 388 ARG C NH1 1 
ATOM   10291 N NH2 . ARG C 1 388 ? 24.941  -18.487 -10.439 1.00 51.50  ? 388 ARG C NH2 1 
ATOM   10292 N N   . GLU C 1 389 ? 18.681  -11.856 -8.974  1.00 28.97  ? 389 GLU C N   1 
ATOM   10293 C CA  . GLU C 1 389 ? 17.608  -10.930 -9.339  1.00 30.46  ? 389 GLU C CA  1 
ATOM   10294 C C   . GLU C 1 389 ? 18.106  -9.501  -9.281  1.00 27.75  ? 389 GLU C C   1 
ATOM   10295 O O   . GLU C 1 389 ? 17.981  -8.851  -8.260  1.00 28.22  ? 389 GLU C O   1 
ATOM   10296 C CB  . GLU C 1 389 ? 16.427  -11.105 -8.390  1.00 31.68  ? 389 GLU C CB  1 
ATOM   10297 C CG  . GLU C 1 389 ? 15.880  -12.527 -8.428  1.00 34.26  ? 389 GLU C CG  1 
ATOM   10298 C CD  . GLU C 1 389 ? 16.718  -13.669 -7.874  1.00 38.10  ? 389 GLU C CD  1 
ATOM   10299 O OE1 . GLU C 1 389 ? 16.390  -14.812 -8.235  1.00 39.61  ? 389 GLU C OE1 1 
ATOM   10300 O OE2 . GLU C 1 389 ? 17.659  -13.451 -7.041  1.00 32.83  ? 389 GLU C OE2 1 
ATOM   10301 N N   . TYR C 1 390 ? 18.594  -9.007  -10.421 1.00 25.18  ? 390 TYR C N   1 
ATOM   10302 C CA  . TYR C 1 390 ? 19.296  -7.738  -10.525 1.00 28.53  ? 390 TYR C CA  1 
ATOM   10303 C C   . TYR C 1 390 ? 18.537  -6.556  -9.880  1.00 31.13  ? 390 TYR C C   1 
ATOM   10304 O O   . TYR C 1 390 ? 19.150  -5.746  -9.200  1.00 26.38  ? 390 TYR C O   1 
ATOM   10305 C CB  . TYR C 1 390 ? 19.468  -7.381  -12.003 1.00 31.16  ? 390 TYR C CB  1 
ATOM   10306 C CG  . TYR C 1 390 ? 20.221  -8.361  -12.876 1.00 33.49  ? 390 TYR C CG  1 
ATOM   10307 C CD1 . TYR C 1 390 ? 21.606  -8.337  -12.928 1.00 37.78  ? 390 TYR C CD1 1 
ATOM   10308 C CD2 . TYR C 1 390 ? 19.554  -9.228  -13.729 1.00 32.21  ? 390 TYR C CD2 1 
ATOM   10309 C CE1 . TYR C 1 390 ? 22.310  -9.169  -13.784 1.00 36.26  ? 390 TYR C CE1 1 
ATOM   10310 C CE2 . TYR C 1 390 ? 20.239  -10.091 -14.571 1.00 31.22  ? 390 TYR C CE2 1 
ATOM   10311 C CZ  . TYR C 1 390 ? 21.619  -10.030 -14.620 1.00 34.26  ? 390 TYR C CZ  1 
ATOM   10312 O OH  . TYR C 1 390 ? 22.336  -10.850 -15.425 1.00 34.29  ? 390 TYR C OH  1 
ATOM   10313 N N   . ASP C 1 391 ? 17.227  -6.387  -10.142 1.00 27.23  ? 391 ASP C N   1 
ATOM   10314 C CA  . ASP C 1 391 ? 16.505  -5.229  -9.615  1.00 30.25  ? 391 ASP C CA  1 
ATOM   10315 C C   . ASP C 1 391 ? 16.471  -5.256  -8.084  1.00 27.21  ? 391 ASP C C   1 
ATOM   10316 O O   . ASP C 1 391 ? 16.418  -4.204  -7.434  1.00 27.73  ? 391 ASP C O   1 
ATOM   10317 C CB  . ASP C 1 391 ? 15.081  -5.125  -10.138 1.00 32.18  ? 391 ASP C CB  1 
ATOM   10318 C CG  . ASP C 1 391 ? 14.929  -4.752  -11.611 1.00 37.75  ? 391 ASP C CG  1 
ATOM   10319 O OD1 . ASP C 1 391 ? 15.958  -4.415  -12.255 1.00 35.65  ? 391 ASP C OD1 1 
ATOM   10320 O OD2 . ASP C 1 391 ? 13.768  -4.842  -12.127 1.00 40.90  ? 391 ASP C OD2 1 
ATOM   10321 N N   . PHE C 1 392 ? 16.566  -6.447  -7.503  1.00 25.35  ? 392 PHE C N   1 
ATOM   10322 C CA  . PHE C 1 392 ? 16.500  -6.582  -6.052  1.00 25.65  ? 392 PHE C CA  1 
ATOM   10323 C C   . PHE C 1 392 ? 17.791  -6.115  -5.352  1.00 25.81  ? 392 PHE C C   1 
ATOM   10324 O O   . PHE C 1 392 ? 17.815  -5.897  -4.139  1.00 23.28  ? 392 PHE C O   1 
ATOM   10325 C CB  . PHE C 1 392 ? 16.188  -8.035  -5.691  1.00 24.89  ? 392 PHE C CB  1 
ATOM   10326 C CG  . PHE C 1 392 ? 15.830  -8.217  -4.236  1.00 24.44  ? 392 PHE C CG  1 
ATOM   10327 C CD1 . PHE C 1 392 ? 14.604  -7.810  -3.754  1.00 25.55  ? 392 PHE C CD1 1 
ATOM   10328 C CD2 . PHE C 1 392 ? 16.751  -8.729  -3.332  1.00 24.04  ? 392 PHE C CD2 1 
ATOM   10329 C CE1 . PHE C 1 392 ? 14.272  -7.964  -2.409  1.00 21.22  ? 392 PHE C CE1 1 
ATOM   10330 C CE2 . PHE C 1 392 ? 16.422  -8.884  -1.992  1.00 22.24  ? 392 PHE C CE2 1 
ATOM   10331 C CZ  . PHE C 1 392 ? 15.192  -8.506  -1.540  1.00 23.44  ? 392 PHE C CZ  1 
ATOM   10332 N N   . TYR C 1 393 ? 18.906  -6.021  -6.089  1.00 25.23  ? 393 TYR C N   1 
ATOM   10333 C CA  . TYR C 1 393 ? 20.183  -5.625  -5.500  1.00 25.05  ? 393 TYR C CA  1 
ATOM   10334 C C   . TYR C 1 393 ? 20.092  -4.261  -4.815  1.00 25.44  ? 393 TYR C C   1 
ATOM   10335 O O   . TYR C 1 393 ? 20.726  -4.022  -3.787  1.00 24.99  ? 393 TYR C O   1 
ATOM   10336 C CB  . TYR C 1 393 ? 21.245  -5.577  -6.598  1.00 26.67  ? 393 TYR C CB  1 
ATOM   10337 C CG  . TYR C 1 393 ? 21.681  -6.894  -7.176  1.00 27.75  ? 393 TYR C CG  1 
ATOM   10338 C CD1 . TYR C 1 393 ? 21.172  -8.103  -6.754  1.00 28.88  ? 393 TYR C CD1 1 
ATOM   10339 C CD2 . TYR C 1 393 ? 22.653  -6.918  -8.150  1.00 27.27  ? 393 TYR C CD2 1 
ATOM   10340 C CE1 . TYR C 1 393 ? 21.622  -9.305  -7.274  1.00 29.84  ? 393 TYR C CE1 1 
ATOM   10341 C CE2 . TYR C 1 393 ? 23.123  -8.096  -8.675  1.00 27.31  ? 393 TYR C CE2 1 
ATOM   10342 C CZ  . TYR C 1 393 ? 22.602  -9.297  -8.246  1.00 28.69  ? 393 TYR C CZ  1 
ATOM   10343 O OH  . TYR C 1 393 ? 23.075  -10.454 -8.778  1.00 27.79  ? 393 TYR C OH  1 
ATOM   10344 N N   . THR C 1 394 ? 19.270  -3.360  -5.342  1.00 24.57  ? 394 THR C N   1 
ATOM   10345 C CA  . THR C 1 394 ? 19.080  -2.052  -4.732  1.00 24.77  ? 394 THR C CA  1 
ATOM   10346 C C   . THR C 1 394 ? 18.371  -2.167  -3.389  1.00 24.83  ? 394 THR C C   1 
ATOM   10347 O O   . THR C 1 394 ? 18.617  -1.354  -2.502  1.00 26.15  ? 394 THR C O   1 
ATOM   10348 C CB  . THR C 1 394 ? 18.348  -1.119  -5.692  1.00 27.46  ? 394 THR C CB  1 
ATOM   10349 O OG1 . THR C 1 394 ? 18.940  -1.250  -6.984  1.00 30.02  ? 394 THR C OG1 1 
ATOM   10350 C CG2 . THR C 1 394 ? 18.422  0.316   -5.238  1.00 30.20  ? 394 THR C CG2 1 
ATOM   10351 N N   . VAL C 1 395 ? 17.499  -3.156  -3.235  1.00 24.08  ? 395 VAL C N   1 
ATOM   10352 C CA  . VAL C 1 395 ? 16.815  -3.368  -1.970  1.00 22.59  ? 395 VAL C CA  1 
ATOM   10353 C C   . VAL C 1 395 ? 17.823  -3.793  -0.911  1.00 24.36  ? 395 VAL C C   1 
ATOM   10354 O O   . VAL C 1 395 ? 17.757  -3.359  0.236   1.00 25.79  ? 395 VAL C O   1 
ATOM   10355 C CB  . VAL C 1 395 ? 15.652  -4.372  -2.063  1.00 22.80  ? 395 VAL C CB  1 
ATOM   10356 C CG1 . VAL C 1 395 ? 15.047  -4.635  -0.714  1.00 24.48  ? 395 VAL C CG1 1 
ATOM   10357 C CG2 . VAL C 1 395 ? 14.567  -3.880  -3.007  1.00 23.01  ? 395 VAL C CG2 1 
ATOM   10358 N N   . LEU C 1 396 ? 18.784  -4.620  -1.291  1.00 24.29  ? 396 LEU C N   1 
ATOM   10359 C CA  . LEU C 1 396 ? 19.810  -5.037  -0.353  1.00 24.34  ? 396 LEU C CA  1 
ATOM   10360 C C   . LEU C 1 396 ? 20.631  -3.838  0.093   1.00 25.99  ? 396 LEU C C   1 
ATOM   10361 O O   . LEU C 1 396 ? 20.949  -3.717  1.269   1.00 26.48  ? 396 LEU C O   1 
ATOM   10362 C CB  . LEU C 1 396 ? 20.691  -6.089  -1.019  1.00 26.32  ? 396 LEU C CB  1 
ATOM   10363 C CG  . LEU C 1 396 ? 19.996  -7.417  -1.295  1.00 28.42  ? 396 LEU C CG  1 
ATOM   10364 C CD1 . LEU C 1 396 ? 20.894  -8.330  -2.114  1.00 29.32  ? 396 LEU C CD1 1 
ATOM   10365 C CD2 . LEU C 1 396 ? 19.565  -8.094  -0.002  1.00 25.81  ? 396 LEU C CD2 1 
ATOM   10366 N N   . PHE C 1 397 ? 20.972  -2.968  -0.857  1.00 23.36  ? 397 PHE C N   1 
ATOM   10367 C CA  . PHE C 1 397 ? 21.672  -1.741  -0.550  1.00 26.54  ? 397 PHE C CA  1 
ATOM   10368 C C   . PHE C 1 397 ? 20.839  -0.904  0.432   1.00 26.84  ? 397 PHE C C   1 
ATOM   10369 O O   . PHE C 1 397 ? 21.344  -0.390  1.424   1.00 25.22  ? 397 PHE C O   1 
ATOM   10370 C CB  . PHE C 1 397 ? 21.963  -1.049  -1.877  1.00 29.15  ? 397 PHE C CB  1 
ATOM   10371 C CG  . PHE C 1 397 ? 22.829  0.179   -1.867  1.00 33.01  ? 397 PHE C CG  1 
ATOM   10372 C CD1 . PHE C 1 397 ? 23.314  0.745   -0.707  1.00 38.20  ? 397 PHE C CD1 1 
ATOM   10373 C CD2 . PHE C 1 397 ? 23.181  0.767   -3.073  1.00 44.70  ? 397 PHE C CD2 1 
ATOM   10374 C CE1 . PHE C 1 397 ? 24.127  1.873   -0.753  1.00 39.97  ? 397 PHE C CE1 1 
ATOM   10375 C CE2 . PHE C 1 397 ? 23.987  1.899   -3.118  1.00 46.39  ? 397 PHE C CE2 1 
ATOM   10376 C CZ  . PHE C 1 397 ? 24.475  2.436   -1.953  1.00 40.52  ? 397 PHE C CZ  1 
ATOM   10377 N N   . GLY C 1 398 ? 19.551  -0.784  0.170   1.00 24.46  ? 398 GLY C N   1 
ATOM   10378 C CA  . GLY C 1 398 ? 18.670  -0.020  1.036   1.00 23.67  ? 398 GLY C CA  1 
ATOM   10379 C C   . GLY C 1 398 ? 18.628  -0.541  2.464   1.00 22.04  ? 398 GLY C C   1 
ATOM   10380 O O   . GLY C 1 398 ? 18.665  0.258   3.387   1.00 25.02  ? 398 GLY C O   1 
ATOM   10381 N N   . VAL C 1 399 ? 18.480  -1.865  2.656   1.00 23.67  ? 399 VAL C N   1 
ATOM   10382 C CA  . VAL C 1 399 ? 18.517  -2.465  3.978   1.00 22.60  ? 399 VAL C CA  1 
ATOM   10383 C C   . VAL C 1 399 ? 19.798  -2.069  4.717   1.00 27.43  ? 399 VAL C C   1 
ATOM   10384 O O   . VAL C 1 399 ? 19.779  -1.703  5.879   1.00 26.43  ? 399 VAL C O   1 
ATOM   10385 C CB  . VAL C 1 399 ? 18.394  -3.992  3.900   1.00 24.55  ? 399 VAL C CB  1 
ATOM   10386 C CG1 . VAL C 1 399 ? 18.609  -4.641  5.272   1.00 24.65  ? 399 VAL C CG1 1 
ATOM   10387 C CG2 . VAL C 1 399 ? 17.062  -4.437  3.311   1.00 26.84  ? 399 VAL C CG2 1 
ATOM   10388 N N   . SER C 1 400 ? 20.945  -2.126  4.037   1.00 27.63  ? 400 SER C N   1 
ATOM   10389 C CA  . SER C 1 400 ? 22.191  -1.748  4.667   1.00 24.65  ? 400 SER C CA  1 
ATOM   10390 C C   . SER C 1 400 ? 22.213  -0.262  5.025   1.00 24.83  ? 400 SER C C   1 
ATOM   10391 O O   . SER C 1 400 ? 22.618  0.116   6.123   1.00 27.83  ? 400 SER C O   1 
ATOM   10392 C CB  . SER C 1 400 ? 23.359  -2.099  3.780   1.00 28.95  ? 400 SER C CB  1 
ATOM   10393 O OG  . SER C 1 400 ? 24.562  -1.568  4.327   1.00 31.25  ? 400 SER C OG  1 
ATOM   10394 N N   . ARG C 1 401 ? 21.866  0.594   4.064   1.00 25.06  ? 401 ARG C N   1 
ATOM   10395 C CA  . ARG C 1 401 ? 21.977  2.033   4.220   1.00 29.54  ? 401 ARG C CA  1 
ATOM   10396 C C   . ARG C 1 401 ? 21.079  2.575   5.348   1.00 27.39  ? 401 ARG C C   1 
ATOM   10397 O O   . ARG C 1 401 ? 21.319  3.666   5.861   1.00 25.43  ? 401 ARG C O   1 
ATOM   10398 C CB  . ARG C 1 401 ? 21.671  2.681   2.874   1.00 33.05  ? 401 ARG C CB  1 
ATOM   10399 C CG  . ARG C 1 401 ? 21.942  4.176   2.800   1.00 37.37  ? 401 ARG C CG  1 
ATOM   10400 C CD  . ARG C 1 401 ? 23.309  4.675   3.272   1.00 33.49  ? 401 ARG C CD  1 
ATOM   10401 N NE  . ARG C 1 401 ? 24.465  4.041   2.671   1.00 30.66  ? 401 ARG C NE  1 
ATOM   10402 C CZ  . ARG C 1 401 ? 25.144  4.504   1.627   1.00 33.21  ? 401 ARG C CZ  1 
ATOM   10403 N NH1 . ARG C 1 401 ? 24.619  5.455   0.886   1.00 31.47  ? 401 ARG C NH1 1 
ATOM   10404 N NH2 . ARG C 1 401 ? 26.280  3.926   1.253   1.00 33.62  ? 401 ARG C NH2 1 
ATOM   10405 N N   . ALA C 1 402 ? 20.060  1.827   5.735   1.00 25.87  ? 402 ALA C N   1 
ATOM   10406 C CA  . ALA C 1 402 ? 19.242  2.165   6.893   1.00 28.25  ? 402 ALA C CA  1 
ATOM   10407 C C   . ALA C 1 402 ? 20.079  2.292   8.175   1.00 25.84  ? 402 ALA C C   1 
ATOM   10408 O O   . ALA C 1 402 ? 19.701  3.051   9.056   1.00 26.43  ? 402 ALA C O   1 
ATOM   10409 C CB  . ALA C 1 402 ? 18.160  1.120   7.083   1.00 26.12  ? 402 ALA C CB  1 
ATOM   10410 N N   . LEU C 1 403 ? 21.158  1.508   8.303   1.00 25.40  ? 403 LEU C N   1 
ATOM   10411 C CA  . LEU C 1 403 ? 22.051  1.600   9.442   1.00 24.94  ? 403 LEU C CA  1 
ATOM   10412 C C   . LEU C 1 403 ? 22.574  3.023   9.604   1.00 28.45  ? 403 LEU C C   1 
ATOM   10413 O O   . LEU C 1 403 ? 22.468  3.633   10.664  1.00 27.06  ? 403 LEU C O   1 
ATOM   10414 C CB  . LEU C 1 403 ? 23.176  0.589   9.256   1.00 26.51  ? 403 LEU C CB  1 
ATOM   10415 C CG  . LEU C 1 403 ? 22.772  -0.877  9.299   1.00 29.33  ? 403 LEU C CG  1 
ATOM   10416 C CD1 . LEU C 1 403 ? 23.950  -1.750  8.900   1.00 33.06  ? 403 LEU C CD1 1 
ATOM   10417 C CD2 . LEU C 1 403 ? 22.232  -1.318  10.658  1.00 33.24  ? 403 LEU C CD2 1 
ATOM   10418 N N   . GLY C 1 404 ? 23.121  3.580   8.533   1.00 29.08  ? 404 GLY C N   1 
ATOM   10419 C CA  . GLY C 1 404 ? 23.610  4.943   8.558   1.00 30.10  ? 404 GLY C CA  1 
ATOM   10420 C C   . GLY C 1 404 ? 22.501  5.984   8.671   1.00 30.62  ? 404 GLY C C   1 
ATOM   10421 O O   . GLY C 1 404 ? 22.645  6.933   9.421   1.00 27.26  ? 404 GLY C O   1 
ATOM   10422 N N   . CYS C 1 405 ? 21.398  5.826   7.933   1.00 27.25  ? 405 CYS C N   1 
ATOM   10423 C CA  . CYS C 1 405 ? 20.323  6.798   7.969   1.00 27.07  ? 405 CYS C CA  1 
ATOM   10424 C C   . CYS C 1 405 ? 19.712  6.905   9.370   1.00 25.03  ? 405 CYS C C   1 
ATOM   10425 O O   . CYS C 1 405 ? 19.307  8.002   9.782   1.00 26.37  ? 405 CYS C O   1 
ATOM   10426 C CB  . CYS C 1 405 ? 19.240  6.465   6.942   1.00 29.28  ? 405 CYS C CB  1 
ATOM   10427 S SG  . CYS C 1 405 ? 19.820  6.701   5.239   1.00 36.68  ? 405 CYS C SG  1 
ATOM   10428 N N   . THR C 1 406 ? 19.506  5.772   10.037  1.00 24.22  ? 406 THR C N   1 
ATOM   10429 C CA  . THR C 1 406 ? 18.906  5.809   11.363  1.00 26.30  ? 406 THR C CA  1 
ATOM   10430 C C   . THR C 1 406 ? 19.897  6.439   12.355  1.00 28.75  ? 406 THR C C   1 
ATOM   10431 O O   . THR C 1 406 ? 19.510  7.232   13.208  1.00 30.17  ? 406 THR C O   1 
ATOM   10432 C CB  . THR C 1 406 ? 18.469  4.452   11.890  1.00 23.43  ? 406 THR C CB  1 
ATOM   10433 O OG1 . THR C 1 406 ? 19.538  3.522   11.767  1.00 25.21  ? 406 THR C OG1 1 
ATOM   10434 C CG2 . THR C 1 406 ? 17.241  3.901   11.183  1.00 27.96  ? 406 THR C CG2 1 
ATOM   10435 N N   . ALA C 1 407 ? 21.164  6.038   12.305  1.00 27.37  ? 407 ALA C N   1 
ATOM   10436 C CA  . ALA C 1 407 ? 22.144  6.643   13.202  1.00 31.07  ? 407 ALA C CA  1 
ATOM   10437 C C   . ALA C 1 407 ? 22.189  8.164   13.009  1.00 29.73  ? 407 ALA C C   1 
ATOM   10438 O O   . ALA C 1 407 ? 22.140  8.930   13.984  1.00 28.20  ? 407 ALA C O   1 
ATOM   10439 C CB  . ALA C 1 407 ? 23.482  5.979   13.010  1.00 33.96  ? 407 ALA C CB  1 
ATOM   10440 N N   . GLN C 1 408 ? 22.218  8.639   11.755  1.00 27.83  ? 408 GLN C N   1 
ATOM   10441 C CA  . GLN C 1 408 ? 22.257  10.073  11.507  1.00 31.50  ? 408 GLN C CA  1 
ATOM   10442 C C   . GLN C 1 408 ? 20.989  10.795  11.997  1.00 35.40  ? 408 GLN C C   1 
ATOM   10443 O O   . GLN C 1 408 ? 21.072  11.931  12.468  1.00 28.39  ? 408 GLN C O   1 
ATOM   10444 C CB  . GLN C 1 408 ? 22.432  10.386  10.021  1.00 34.42  ? 408 GLN C CB  1 
ATOM   10445 C CG  . GLN C 1 408 ? 23.810  10.007  9.476   1.00 38.83  ? 408 GLN C CG  1 
ATOM   10446 C CD  . GLN C 1 408 ? 24.038  10.405  8.034   1.00 38.35  ? 408 GLN C CD  1 
ATOM   10447 O OE1 . GLN C 1 408 ? 23.660  11.486  7.584   1.00 47.75  ? 408 GLN C OE1 1 
ATOM   10448 N NE2 . GLN C 1 408 ? 24.599  9.488   7.262   1.00 40.93  ? 408 GLN C NE2 1 
ATOM   10449 N N   . ALA C 1 409 ? 19.802  10.208  11.767  1.00 30.81  ? 409 ALA C N   1 
ATOM   10450 C CA  . ALA C 1 409 ? 18.532  10.828  12.136  1.00 27.93  ? 409 ALA C CA  1 
ATOM   10451 C C   . ALA C 1 409 ? 18.397  10.961  13.657  1.00 29.00  ? 409 ALA C C   1 
ATOM   10452 O O   . ALA C 1 409 ? 17.919  11.974  14.163  1.00 33.51  ? 409 ALA C O   1 
ATOM   10453 C CB  . ALA C 1 409 ? 17.381  10.033  11.559  1.00 28.54  ? 409 ALA C CB  1 
ATOM   10454 N N   . ILE C 1 410 ? 18.810  9.929   14.380  1.00 28.09  ? 410 ILE C N   1 
ATOM   10455 C CA  . ILE C 1 410 ? 18.835  9.955   15.824  1.00 29.05  ? 410 ILE C CA  1 
ATOM   10456 C C   . ILE C 1 410 ? 19.773  11.068  16.320  1.00 32.69  ? 410 ILE C C   1 
ATOM   10457 O O   . ILE C 1 410 ? 19.401  11.853  17.176  1.00 29.73  ? 410 ILE C O   1 
ATOM   10458 C CB  . ILE C 1 410 ? 19.269  8.594   16.350  1.00 27.65  ? 410 ILE C CB  1 
ATOM   10459 C CG1 . ILE C 1 410 ? 18.205  7.532   16.074  1.00 26.95  ? 410 ILE C CG1 1 
ATOM   10460 C CG2 . ILE C 1 410 ? 19.631  8.649   17.834  1.00 30.58  ? 410 ILE C CG2 1 
ATOM   10461 C CD1 . ILE C 1 410 ? 18.727  6.138   16.251  1.00 30.61  ? 410 ILE C CD1 1 
ATOM   10462 N N   . LEU C 1 411 ? 20.993  11.125  15.804  1.00 33.74  ? 411 LEU C N   1 
ATOM   10463 C CA  . LEU C 1 411 ? 21.994  12.071  16.288  1.00 32.38  ? 411 LEU C CA  1 
ATOM   10464 C C   . LEU C 1 411 ? 21.551  13.501  16.037  1.00 33.68  ? 411 LEU C C   1 
ATOM   10465 O O   . LEU C 1 411 ? 21.710  14.351  16.907  1.00 31.77  ? 411 LEU C O   1 
ATOM   10466 C CB  . LEU C 1 411 ? 23.328  11.788  15.602  1.00 28.40  ? 411 LEU C CB  1 
ATOM   10467 C CG  . LEU C 1 411 ? 23.970  10.487  16.064  1.00 29.61  ? 411 LEU C CG  1 
ATOM   10468 C CD1 . LEU C 1 411 ? 25.225  10.180  15.271  1.00 31.83  ? 411 LEU C CD1 1 
ATOM   10469 C CD2 . LEU C 1 411 ? 24.293  10.538  17.538  1.00 38.20  ? 411 LEU C CD2 1 
ATOM   10470 N N   . VAL C 1 412 ? 21.009  13.770  14.850  1.00 31.19  ? 412 VAL C N   1 
ATOM   10471 C CA  . VAL C 1 412 ? 20.749  15.140  14.450  1.00 33.79  ? 412 VAL C CA  1 
ATOM   10472 C C   . VAL C 1 412 ? 19.527  15.674  15.214  1.00 34.72  ? 412 VAL C C   1 
ATOM   10473 O O   . VAL C 1 412 ? 19.401  16.896  15.434  1.00 31.36  ? 412 VAL C O   1 
ATOM   10474 C CB  . VAL C 1 412 ? 20.623  15.244  12.921  1.00 38.53  ? 412 VAL C CB  1 
ATOM   10475 C CG1 . VAL C 1 412 ? 19.876  16.491  12.512  1.00 50.59  ? 412 VAL C CG1 1 
ATOM   10476 C CG2 . VAL C 1 412 ? 21.986  15.194  12.234  1.00 39.83  ? 412 VAL C CG2 1 
ATOM   10477 N N   . ARG C 1 413 ? 18.614  14.767  15.596  1.00 30.69  ? 413 ARG C N   1 
ATOM   10478 C CA  . ARG C 1 413 ? 17.519  15.107  16.512  1.00 34.51  ? 413 ARG C CA  1 
ATOM   10479 C C   . ARG C 1 413 ? 18.040  15.277  17.949  1.00 34.39  ? 413 ARG C C   1 
ATOM   10480 O O   . ARG C 1 413 ? 17.490  16.090  18.696  1.00 37.15  ? 413 ARG C O   1 
ATOM   10481 C CB  . ARG C 1 413 ? 16.382  14.079  16.486  1.00 32.83  ? 413 ARG C CB  1 
ATOM   10482 C CG  . ARG C 1 413 ? 15.649  13.970  15.161  1.00 31.40  ? 413 ARG C CG  1 
ATOM   10483 C CD  . ARG C 1 413 ? 14.652  15.048  14.882  1.00 31.91  ? 413 ARG C CD  1 
ATOM   10484 N NE  . ARG C 1 413 ? 15.048  16.391  15.275  1.00 40.48  ? 413 ARG C NE  1 
ATOM   10485 C CZ  . ARG C 1 413 ? 15.790  17.235  14.552  1.00 46.02  ? 413 ARG C CZ  1 
ATOM   10486 N NH1 . ARG C 1 413 ? 16.215  16.906  13.344  1.00 42.36  ? 413 ARG C NH1 1 
ATOM   10487 N NH2 . ARG C 1 413 ? 16.128  18.414  15.052  1.00 42.04  ? 413 ARG C NH2 1 
ATOM   10488 N N   . GLY C 1 414 ? 19.091  14.534  18.318  1.00 31.73  ? 414 GLY C N   1 
ATOM   10489 C CA  . GLY C 1 414 ? 19.868  14.779  19.529  1.00 35.41  ? 414 GLY C CA  1 
ATOM   10490 C C   . GLY C 1 414 ? 20.544  16.155  19.582  1.00 34.79  ? 414 GLY C C   1 
ATOM   10491 O O   . GLY C 1 414 ? 20.476  16.847  20.602  1.00 40.30  ? 414 GLY C O   1 
ATOM   10492 N N   . TYR C 1 415 ? 21.180  16.559  18.481  1.00 32.93  ? 415 TYR C N   1 
ATOM   10493 C CA  . TYR C 1 415 ? 21.817  17.861  18.334  1.00 33.30  ? 415 TYR C CA  1 
ATOM   10494 C C   . TYR C 1 415 ? 20.828  19.011  18.247  1.00 35.97  ? 415 TYR C C   1 
ATOM   10495 O O   . TYR C 1 415 ? 21.214  20.156  18.436  1.00 37.69  ? 415 TYR C O   1 
ATOM   10496 C CB  . TYR C 1 415 ? 22.567  17.976  17.001  1.00 32.56  ? 415 TYR C CB  1 
ATOM   10497 C CG  . TYR C 1 415 ? 23.751  17.073  16.804  1.00 31.79  ? 415 TYR C CG  1 
ATOM   10498 C CD1 . TYR C 1 415 ? 24.146  16.181  17.771  1.00 29.26  ? 415 TYR C CD1 1 
ATOM   10499 C CD2 . TYR C 1 415 ? 24.428  17.055  15.591  1.00 34.97  ? 415 TYR C CD2 1 
ATOM   10500 C CE1 . TYR C 1 415 ? 25.199  15.311  17.562  1.00 31.70  ? 415 TYR C CE1 1 
ATOM   10501 C CE2 . TYR C 1 415 ? 25.492  16.197  15.376  1.00 37.48  ? 415 TYR C CE2 1 
ATOM   10502 C CZ  . TYR C 1 415 ? 25.898  15.337  16.373  1.00 32.73  ? 415 TYR C CZ  1 
ATOM   10503 O OH  . TYR C 1 415 ? 26.941  14.423  16.232  1.00 43.30  ? 415 TYR C OH  1 
ATOM   10504 N N   . MET C 1 416 ? 19.597  18.715  17.802  1.00 38.37  ? 416 MET C N   1 
ATOM   10505 C CA  . MET C 1 416 ? 18.536  19.692  17.603  1.00 33.40  ? 416 MET C CA  1 
ATOM   10506 C C   . MET C 1 416 ? 18.849  20.652  16.464  1.00 32.38  ? 416 MET C C   1 
ATOM   10507 O O   . MET C 1 416 ? 18.431  21.800  16.496  1.00 30.89  ? 416 MET C O   1 
ATOM   10508 C CB  . MET C 1 416 ? 18.233  20.469  18.892  1.00 38.36  ? 416 MET C CB  1 
ATOM   10509 C CG  . MET C 1 416 ? 17.657  19.554  19.953  1.00 44.38  ? 416 MET C CG  1 
ATOM   10510 S SD  . MET C 1 416 ? 17.120  20.454  21.435  1.00 57.51  ? 416 MET C SD  1 
ATOM   10511 C CE  . MET C 1 416 ? 16.860  19.078  22.550  1.00 58.33  ? 416 MET C CE  1 
ATOM   10512 N N   . LEU C 1 417 ? 19.377  20.133  15.352  1.00 34.06  ? 417 LEU C N   1 
ATOM   10513 C CA  . LEU C 1 417 ? 19.555  20.960  14.174  1.00 34.36  ? 417 LEU C CA  1 
ATOM   10514 C C   . LEU C 1 417 ? 18.212  21.383  13.608  1.00 34.26  ? 417 LEU C C   1 
ATOM   10515 O O   . LEU C 1 417 ? 17.201  20.716  13.774  1.00 36.97  ? 417 LEU C O   1 
ATOM   10516 C CB  . LEU C 1 417 ? 20.364  20.214  13.110  1.00 35.26  ? 417 LEU C CB  1 
ATOM   10517 C CG  . LEU C 1 417 ? 21.747  19.752  13.529  1.00 38.45  ? 417 LEU C CG  1 
ATOM   10518 C CD1 . LEU C 1 417 ? 22.524  19.235  12.306  1.00 39.42  ? 417 LEU C CD1 1 
ATOM   10519 C CD2 . LEU C 1 417 ? 22.481  20.877  14.261  1.00 36.55  ? 417 LEU C CD2 1 
ATOM   10520 N N   . PRO C 1 418 ? 18.169  22.575  12.996  1.00 35.57  ? 418 PRO C N   1 
ATOM   10521 C CA  . PRO C 1 418 ? 16.937  23.136  12.428  1.00 34.05  ? 418 PRO C CA  1 
ATOM   10522 C C   . PRO C 1 418 ? 16.529  22.577  11.061  1.00 34.70  ? 418 PRO C C   1 
ATOM   10523 O O   . PRO C 1 418 ? 17.232  21.757  10.498  1.00 33.01  ? 418 PRO C O   1 
ATOM   10524 C CB  . PRO C 1 418 ? 17.290  24.627  12.254  1.00 33.56  ? 418 PRO C CB  1 
ATOM   10525 C CG  . PRO C 1 418 ? 18.805  24.652  12.112  1.00 33.51  ? 418 PRO C CG  1 
ATOM   10526 C CD  . PRO C 1 418 ? 19.318  23.495  12.933  1.00 33.30  ? 418 PRO C CD  1 
ATOM   10527 N N   . ILE C 1 419 ? 15.389  23.048  10.562  1.00 32.65  ? 419 ILE C N   1 
ATOM   10528 C CA  . ILE C 1 419 ? 14.825  22.624  9.302   1.00 34.02  ? 419 ILE C CA  1 
ATOM   10529 C C   . ILE C 1 419 ? 15.778  23.030  8.195   1.00 37.21  ? 419 ILE C C   1 
ATOM   10530 O O   . ILE C 1 419 ? 16.369  24.098  8.252   1.00 33.74  ? 419 ILE C O   1 
ATOM   10531 C CB  . ILE C 1 419 ? 13.428  23.229  9.107   1.00 34.94  ? 419 ILE C CB  1 
ATOM   10532 C CG1 . ILE C 1 419 ? 12.711  22.610  7.910   1.00 31.95  ? 419 ILE C CG1 1 
ATOM   10533 C CG2 . ILE C 1 419 ? 13.445  24.757  9.022   1.00 37.11  ? 419 ILE C CG2 1 
ATOM   10534 C CD1 . ILE C 1 419 ? 11.257  22.994  7.830   1.00 36.14  ? 419 ILE C CD1 1 
ATOM   10535 N N   . GLU C 1 420 ? 15.930  22.167  7.194   1.00 31.74  ? 420 GLU C N   1 
ATOM   10536 C CA  . GLU C 1 420 ? 16.827  22.482  6.093   1.00 34.81  ? 420 GLU C CA  1 
ATOM   10537 C C   . GLU C 1 420 ? 16.043  23.369  5.134   1.00 35.07  ? 420 GLU C C   1 
ATOM   10538 O O   . GLU C 1 420 ? 14.938  23.010  4.719   1.00 38.71  ? 420 GLU C O   1 
ATOM   10539 C CB  . GLU C 1 420 ? 17.385  21.162  5.528   1.00 37.74  ? 420 GLU C CB  1 
ATOM   10540 C CG  . GLU C 1 420 ? 18.142  21.321  4.218   1.00 41.74  ? 420 GLU C CG  1 
ATOM   10541 C CD  . GLU C 1 420 ? 18.850  20.087  3.670   1.00 46.77  ? 420 GLU C CD  1 
ATOM   10542 O OE1 . GLU C 1 420 ? 19.092  20.076  2.447   1.00 46.61  ? 420 GLU C OE1 1 
ATOM   10543 O OE2 . GLU C 1 420 ? 19.204  19.162  4.456   1.00 49.00  ? 420 GLU C OE2 1 
ATOM   10544 N N   . ARG C 1 421 ? 16.576  24.552  4.789   1.00 32.19  ? 421 ARG C N   1 
ATOM   10545 C CA  . ARG C 1 421 ? 15.869  25.458  3.896   1.00 35.26  ? 421 ARG C CA  1 
ATOM   10546 C C   . ARG C 1 421 ? 16.868  26.379  3.182   1.00 40.19  ? 421 ARG C C   1 
ATOM   10547 O O   . ARG C 1 421 ? 17.040  27.533  3.558   1.00 36.85  ? 421 ARG C O   1 
ATOM   10548 C CB  . ARG C 1 421 ? 14.841  26.288  4.678   1.00 40.50  ? 421 ARG C CB  1 
ATOM   10549 C CG  . ARG C 1 421 ? 13.647  26.807  3.874   1.00 45.46  ? 421 ARG C CG  1 
ATOM   10550 C CD  . ARG C 1 421 ? 13.797  28.059  3.027   1.00 55.32  ? 421 ARG C CD  1 
ATOM   10551 N NE  . ARG C 1 421 ? 12.554  28.417  2.321   1.00 59.58  ? 421 ARG C NE  1 
ATOM   10552 C CZ  . ARG C 1 421 ? 12.449  28.716  1.017   1.00 71.00  ? 421 ARG C CZ  1 
ATOM   10553 N NH1 . ARG C 1 421 ? 13.517  28.742  0.233   1.00 76.64  ? 421 ARG C NH1 1 
ATOM   10554 N NH2 . ARG C 1 421 ? 11.266  28.994  0.483   1.00 62.49  ? 421 ARG C NH2 1 
ATOM   10555 N N   . PRO C 1 422 ? 17.535  25.913  2.105   1.00 37.19  ? 422 PRO C N   1 
ATOM   10556 C CA  . PRO C 1 422 ? 18.348  26.792  1.272   1.00 33.60  ? 422 PRO C CA  1 
ATOM   10557 C C   . PRO C 1 422 ? 17.513  27.803  0.509   1.00 34.14  ? 422 PRO C C   1 
ATOM   10558 O O   . PRO C 1 422 ? 16.281  27.729  0.454   1.00 33.70  ? 422 PRO C O   1 
ATOM   10559 C CB  . PRO C 1 422 ? 19.026  25.863  0.264   1.00 33.55  ? 422 PRO C CB  1 
ATOM   10560 C CG  . PRO C 1 422 ? 18.124  24.636  0.219   1.00 36.82  ? 422 PRO C CG  1 
ATOM   10561 C CD  . PRO C 1 422 ? 17.489  24.536  1.597   1.00 35.95  ? 422 PRO C CD  1 
ATOM   10562 N N   . LYS C 1 423 ? 18.221  28.749  -0.100  1.00 34.29  ? 423 LYS C N   1 
ATOM   10563 C CA  . LYS C 1 423 ? 17.635  29.754  -0.957  1.00 33.74  ? 423 LYS C CA  1 
ATOM   10564 C C   . LYS C 1 423 ? 17.835  29.284  -2.395  1.00 35.84  ? 423 LYS C C   1 
ATOM   10565 O O   . LYS C 1 423 ? 18.912  28.813  -2.743  1.00 36.81  ? 423 LYS C O   1 
ATOM   10566 C CB  . LYS C 1 423 ? 18.355  31.088  -0.705  1.00 40.67  ? 423 LYS C CB  1 
ATOM   10567 C CG  . LYS C 1 423 ? 17.852  32.272  -1.522  1.00 47.92  ? 423 LYS C CG  1 
ATOM   10568 C CD  . LYS C 1 423 ? 16.535  32.828  -0.993  1.00 62.83  ? 423 LYS C CD  1 
ATOM   10569 C CE  . LYS C 1 423 ? 15.782  33.667  -2.003  1.00 69.61  ? 423 LYS C CE  1 
ATOM   10570 N NZ  . LYS C 1 423 ? 14.598  34.307  -1.384  1.00 76.91  ? 423 LYS C NZ  1 
ATOM   10571 N N   . SER C 1 424 ? 16.819  29.423  -3.237  1.00 35.13  ? 424 SER C N   1 
ATOM   10572 C CA  . SER C 1 424 ? 16.964  29.103  -4.643  1.00 42.96  ? 424 SER C CA  1 
ATOM   10573 C C   . SER C 1 424 ? 17.178  30.413  -5.398  1.00 42.08  ? 424 SER C C   1 
ATOM   10574 O O   . SER C 1 424 ? 16.744  31.441  -4.920  1.00 39.97  ? 424 SER C O   1 
ATOM   10575 C CB  . SER C 1 424 ? 15.749  28.314  -5.163  1.00 40.47  ? 424 SER C CB  1 
ATOM   10576 O OG  . SER C 1 424 ? 14.558  29.093  -5.154  1.00 37.21  ? 424 SER C OG  1 
ATOM   10577 N N   . ILE C 1 425 ? 17.789  30.341  -6.587  1.00 41.52  ? 425 ILE C N   1 
ATOM   10578 C CA  . ILE C 1 425 ? 17.994  31.489  -7.449  1.00 37.62  ? 425 ILE C CA  1 
ATOM   10579 C C   . ILE C 1 425 ? 17.354  31.211  -8.798  1.00 39.11  ? 425 ILE C C   1 
ATOM   10580 O O   . ILE C 1 425 ? 17.157  30.061  -9.194  1.00 37.54  ? 425 ILE C O   1 
ATOM   10581 C CB  . ILE C 1 425 ? 19.496  31.814  -7.605  1.00 41.12  ? 425 ILE C CB  1 
ATOM   10582 C CG1 . ILE C 1 425 ? 20.222  30.770  -8.469  1.00 44.78  ? 425 ILE C CG1 1 
ATOM   10583 C CG2 . ILE C 1 425 ? 20.143  32.005  -6.241  1.00 42.52  ? 425 ILE C CG2 1 
ATOM   10584 C CD1 . ILE C 1 425 ? 21.758  30.833  -8.438  1.00 47.19  ? 425 ILE C CD1 1 
ATOM   10585 N N   . THR C 1 426 ? 17.076  32.300  -9.520  1.00 35.51  ? 426 THR C N   1 
ATOM   10586 C CA  . THR C 1 426 ? 16.523  32.235  -10.855 1.00 34.22  ? 426 THR C CA  1 
ATOM   10587 C C   . THR C 1 426 ? 17.601  32.463  -11.920 1.00 41.43  ? 426 THR C C   1 
ATOM   10588 O O   . THR C 1 426 ? 18.606  33.140  -11.694 1.00 42.07  ? 426 THR C O   1 
ATOM   10589 C CB  . THR C 1 426 ? 15.394  33.253  -11.044 1.00 40.05  ? 426 THR C CB  1 
ATOM   10590 O OG1 . THR C 1 426 ? 15.978  34.560  -11.033 1.00 40.18  ? 426 THR C OG1 1 
ATOM   10591 C CG2 . THR C 1 426 ? 14.297  33.147  -10.001 1.00 39.96  ? 426 THR C CG2 1 
ATOM   10592 N N   . THR C 1 427 ? 17.313  31.950  -13.116 1.00 42.91  ? 427 THR C N   1 
ATOM   10593 C CA  . THR C 1 427 ? 18.169  32.118  -14.273 1.00 47.86  ? 427 THR C CA  1 
ATOM   10594 C C   . THR C 1 427 ? 18.062  33.567  -14.743 1.00 51.15  ? 427 THR C C   1 
ATOM   10595 O O   . THR C 1 427 ? 19.023  34.102  -15.282 1.00 46.11  ? 427 THR C O   1 
ATOM   10596 C CB  . THR C 1 427 ? 17.851  31.090  -15.372 1.00 46.54  ? 427 THR C CB  1 
ATOM   10597 O OG1 . THR C 1 427 ? 17.986  29.778  -14.829 1.00 39.22  ? 427 THR C OG1 1 
ATOM   10598 C CG2 . THR C 1 427 ? 18.765  31.174  -16.581 1.00 42.80  ? 427 THR C CG2 1 
ATOM   10599 N N   . ARG C 1 428 ? 16.910  34.205  -14.516 1.00 52.41  ? 428 ARG C N   1 
ATOM   10600 C CA  . ARG C 1 428 ? 16.760  35.602  -14.889 1.00 57.44  ? 428 ARG C CA  1 
ATOM   10601 C C   . ARG C 1 428 ? 17.768  36.414  -14.072 1.00 49.21  ? 428 ARG C C   1 
ATOM   10602 O O   . ARG C 1 428 ? 18.548  37.187  -14.616 1.00 52.93  ? 428 ARG C O   1 
ATOM   10603 C CB  . ARG C 1 428 ? 15.312  36.075  -14.694 1.00 68.50  ? 428 ARG C CB  1 
ATOM   10604 C CG  . ARG C 1 428 ? 15.050  37.506  -15.158 1.00 73.64  ? 428 ARG C CG  1 
ATOM   10605 C CD  . ARG C 1 428 ? 14.096  38.282  -14.257 1.00 71.21  ? 428 ARG C CD  1 
ATOM   10606 N NE  . ARG C 1 428 ? 14.413  38.237  -12.824 1.00 77.37  ? 428 ARG C NE  1 
ATOM   10607 C CZ  . ARG C 1 428 ? 15.238  39.058  -12.168 1.00 78.46  ? 428 ARG C CZ  1 
ATOM   10608 N NH1 . ARG C 1 428 ? 15.879  40.020  -12.813 1.00 86.29  ? 428 ARG C NH1 1 
ATOM   10609 N NH2 . ARG C 1 428 ? 15.411  38.924  -10.859 1.00 68.49  ? 428 ARG C NH2 1 
ATOM   10610 N N   . TRP C 1 429 ? 17.783  36.190  -12.761 1.00 44.40  ? 429 TRP C N   1 
ATOM   10611 C CA  . TRP C 1 429 ? 18.708  36.876  -11.885 1.00 45.76  ? 429 TRP C CA  1 
ATOM   10612 C C   . TRP C 1 429 ? 20.162  36.601  -12.264 1.00 53.31  ? 429 TRP C C   1 
ATOM   10613 O O   . TRP C 1 429 ? 20.964  37.540  -12.324 1.00 45.92  ? 429 TRP C O   1 
ATOM   10614 C CB  . TRP C 1 429 ? 18.449  36.497  -10.433 1.00 43.27  ? 429 TRP C CB  1 
ATOM   10615 C CG  . TRP C 1 429 ? 19.370  37.134  -9.438  1.00 43.86  ? 429 TRP C CG  1 
ATOM   10616 C CD1 . TRP C 1 429 ? 19.266  38.397  -8.930  1.00 45.99  ? 429 TRP C CD1 1 
ATOM   10617 C CD2 . TRP C 1 429 ? 20.516  36.542  -8.790  1.00 51.81  ? 429 TRP C CD2 1 
ATOM   10618 N NE1 . TRP C 1 429 ? 20.249  38.616  -8.001  1.00 50.03  ? 429 TRP C NE1 1 
ATOM   10619 C CE2 . TRP C 1 429 ? 21.043  37.511  -7.908  1.00 47.18  ? 429 TRP C CE2 1 
ATOM   10620 C CE3 . TRP C 1 429 ? 21.169  35.307  -8.878  1.00 51.01  ? 429 TRP C CE3 1 
ATOM   10621 C CZ2 . TRP C 1 429 ? 22.171  37.280  -7.129  1.00 54.10  ? 429 TRP C CZ2 1 
ATOM   10622 C CZ3 . TRP C 1 429 ? 22.283  35.073  -8.099  1.00 53.18  ? 429 TRP C CZ3 1 
ATOM   10623 C CH2 . TRP C 1 429 ? 22.777  36.048  -7.235  1.00 53.20  ? 429 TRP C CH2 1 
ATOM   10624 N N   . VAL C 1 430 ? 20.516  35.319  -12.461 1.00 38.85  ? 430 VAL C N   1 
ATOM   10625 C CA  . VAL C 1 430 ? 21.891  34.965  -12.771 1.00 43.86  ? 430 VAL C CA  1 
ATOM   10626 C C   . VAL C 1 430 ? 22.368  35.747  -14.001 1.00 49.74  ? 430 VAL C C   1 
ATOM   10627 O O   . VAL C 1 430 ? 23.472  36.276  -13.979 1.00 49.62  ? 430 VAL C O   1 
ATOM   10628 C CB  . VAL C 1 430 ? 22.069  33.449  -12.977 1.00 42.24  ? 430 VAL C CB  1 
ATOM   10629 C CG1 . VAL C 1 430 ? 23.400  33.106  -13.625 1.00 40.67  ? 430 VAL C CG1 1 
ATOM   10630 C CG2 . VAL C 1 430 ? 21.908  32.693  -11.659 1.00 41.75  ? 430 VAL C CG2 1 
ATOM   10631 N N   . LYS C 1 431 ? 21.551  35.770  -15.067 1.00 53.23  ? 431 LYS C N   1 
ATOM   10632 C CA  . LYS C 1 431 ? 21.879  36.426  -16.324 1.00 62.54  ? 431 LYS C CA  1 
ATOM   10633 C C   . LYS C 1 431 ? 22.218  37.901  -16.128 1.00 58.13  ? 431 LYS C C   1 
ATOM   10634 O O   . LYS C 1 431 ? 23.046  38.443  -16.842 1.00 66.03  ? 431 LYS C O   1 
ATOM   10635 C CB  . LYS C 1 431 ? 20.684  36.417  -17.278 1.00 62.61  ? 431 LYS C CB  1 
ATOM   10636 C CG  . LYS C 1 431 ? 20.509  35.177  -18.131 1.00 61.99  ? 431 LYS C CG  1 
ATOM   10637 C CD  . LYS C 1 431 ? 19.457  35.403  -19.175 1.00 66.60  ? 431 LYS C CD  1 
ATOM   10638 C CE  . LYS C 1 431 ? 18.779  34.128  -19.616 1.00 73.45  ? 431 LYS C CE  1 
ATOM   10639 N NZ  . LYS C 1 431 ? 17.743  34.396  -20.639 1.00 80.59  ? 431 LYS C NZ  1 
ATOM   10640 N N   . GLU C 1 432 ? 21.509  38.537  -15.201 1.00 61.14  ? 432 GLU C N   1 
ATOM   10641 C CA  . GLU C 1 432 ? 21.539  39.969  -15.003 1.00 66.85  ? 432 GLU C CA  1 
ATOM   10642 C C   . GLU C 1 432 ? 22.774  40.392  -14.201 1.00 65.77  ? 432 GLU C C   1 
ATOM   10643 O O   . GLU C 1 432 ? 23.314  41.462  -14.446 1.00 74.68  ? 432 GLU C O   1 
ATOM   10644 C CB  . GLU C 1 432 ? 20.250  40.366  -14.286 1.00 69.46  ? 432 GLU C CB  1 
ATOM   10645 C CG  . GLU C 1 432 ? 20.014  41.859  -14.220 1.00 80.08  ? 432 GLU C CG  1 
ATOM   10646 C CD  . GLU C 1 432 ? 19.059  42.263  -13.112 1.00 93.74  ? 432 GLU C CD  1 
ATOM   10647 O OE1 . GLU C 1 432 ? 19.111  43.433  -12.692 1.00 106.75 ? 432 GLU C OE1 1 
ATOM   10648 O OE2 . GLU C 1 432 ? 18.263  41.407  -12.673 1.00 100.76 ? 432 GLU C OE2 1 
ATOM   10649 N N   . VAL C 1 433 ? 23.222  39.571  -13.244 1.00 55.84  ? 433 VAL C N   1 
ATOM   10650 C CA  . VAL C 1 433 ? 24.272  39.967  -12.317 1.00 51.25  ? 433 VAL C CA  1 
ATOM   10651 C C   . VAL C 1 433 ? 25.573  39.193  -12.546 1.00 52.73  ? 433 VAL C C   1 
ATOM   10652 O O   . VAL C 1 433 ? 26.575  39.527  -11.909 1.00 50.82  ? 433 VAL C O   1 
ATOM   10653 C CB  . VAL C 1 433 ? 23.838  39.758  -10.853 1.00 51.31  ? 433 VAL C CB  1 
ATOM   10654 C CG1 . VAL C 1 433 ? 22.526  40.454  -10.525 1.00 53.12  ? 433 VAL C CG1 1 
ATOM   10655 C CG2 . VAL C 1 433 ? 23.761  38.274  -10.508 1.00 58.54  ? 433 VAL C CG2 1 
ATOM   10656 N N   . ALA C 1 434 ? 25.551  38.097  -13.324 1.00 46.90  ? 434 ALA C N   1 
ATOM   10657 C CA  . ALA C 1 434 ? 26.658  37.145  -13.305 1.00 49.80  ? 434 ALA C CA  1 
ATOM   10658 C C   . ALA C 1 434 ? 27.975  37.807  -13.741 1.00 53.40  ? 434 ALA C C   1 
ATOM   10659 O O   . ALA C 1 434 ? 28.992  37.635  -13.065 1.00 48.97  ? 434 ALA C O   1 
ATOM   10660 C CB  . ALA C 1 434 ? 26.365  35.952  -14.181 1.00 55.44  ? 434 ALA C CB  1 
ATOM   10661 N N   . GLU C 1 435 ? 27.951  38.526  -14.873 1.00 55.44  ? 435 GLU C N   1 
ATOM   10662 C CA  . GLU C 1 435 ? 29.107  39.266  -15.376 1.00 68.38  ? 435 GLU C CA  1 
ATOM   10663 C C   . GLU C 1 435 ? 29.819  40.006  -14.244 1.00 62.12  ? 435 GLU C C   1 
ATOM   10664 O O   . GLU C 1 435 ? 31.004  39.789  -14.030 1.00 66.91  ? 435 GLU C O   1 
ATOM   10665 C CB  . GLU C 1 435 ? 28.692  40.288  -16.436 1.00 73.01  ? 435 GLU C CB  1 
ATOM   10666 C CG  . GLU C 1 435 ? 28.145  39.656  -17.707 1.00 87.12  ? 435 GLU C CG  1 
ATOM   10667 C CD  . GLU C 1 435 ? 27.558  40.622  -18.728 1.00 92.75  ? 435 GLU C CD  1 
ATOM   10668 O OE1 . GLU C 1 435 ? 27.593  40.307  -19.935 1.00 89.57  ? 435 GLU C OE1 1 
ATOM   10669 O OE2 . GLU C 1 435 ? 27.085  41.699  -18.318 1.00 99.38  ? 435 GLU C OE2 1 
ATOM   10670 N N   . SER C 1 436 ? 29.067  40.815  -13.492 1.00 58.81  ? 436 SER C N   1 
ATOM   10671 C CA  . SER C 1 436 ? 29.603  41.716  -12.483 1.00 63.78  ? 436 SER C CA  1 
ATOM   10672 C C   . SER C 1 436 ? 29.970  41.033  -11.161 1.00 62.83  ? 436 SER C C   1 
ATOM   10673 O O   . SER C 1 436 ? 30.495  41.693  -10.261 1.00 59.75  ? 436 SER C O   1 
ATOM   10674 C CB  . SER C 1 436 ? 28.602  42.800  -12.209 1.00 68.47  ? 436 SER C CB  1 
ATOM   10675 O OG  . SER C 1 436 ? 27.513  42.272  -11.464 1.00 77.68  ? 436 SER C OG  1 
ATOM   10676 N N   . LEU C 1 437 ? 29.640  39.748  -10.981 1.00 59.44  ? 437 LEU C N   1 
ATOM   10677 C CA  . LEU C 1 437 ? 30.042  39.065  -9.757  1.00 54.37  ? 437 LEU C CA  1 
ATOM   10678 C C   . LEU C 1 437 ? 31.542  38.803  -9.807  1.00 45.15  ? 437 LEU C C   1 
ATOM   10679 O O   . LEU C 1 437 ? 32.106  38.584  -10.879 1.00 48.02  ? 437 LEU C O   1 
ATOM   10680 C CB  . LEU C 1 437 ? 29.310  37.723  -9.595  1.00 57.72  ? 437 LEU C CB  1 
ATOM   10681 C CG  . LEU C 1 437 ? 27.798  37.768  -9.379  1.00 54.16  ? 437 LEU C CG  1 
ATOM   10682 C CD1 . LEU C 1 437 ? 27.225  36.358  -9.437  1.00 52.16  ? 437 LEU C CD1 1 
ATOM   10683 C CD2 . LEU C 1 437 ? 27.455  38.435  -8.056  1.00 49.78  ? 437 LEU C CD2 1 
ATOM   10684 N N   . PRO C 1 438 ? 32.199  38.745  -8.633  1.00 41.07  ? 438 PRO C N   1 
ATOM   10685 C CA  . PRO C 1 438 ? 33.594  38.333  -8.549  1.00 40.82  ? 438 PRO C CA  1 
ATOM   10686 C C   . PRO C 1 438 ? 33.844  36.833  -8.723  1.00 52.74  ? 438 PRO C C   1 
ATOM   10687 O O   . PRO C 1 438 ? 32.962  36.008  -8.466  1.00 46.31  ? 438 PRO C O   1 
ATOM   10688 C CB  . PRO C 1 438 ? 33.969  38.755  -7.131  1.00 39.52  ? 438 PRO C CB  1 
ATOM   10689 C CG  . PRO C 1 438 ? 32.683  38.706  -6.354  1.00 41.41  ? 438 PRO C CG  1 
ATOM   10690 C CD  . PRO C 1 438 ? 31.607  39.098  -7.334  1.00 40.10  ? 438 PRO C CD  1 
ATOM   10691 N N   . VAL C 1 439 ? 35.087  36.491  -9.089  1.00 46.82  ? 439 VAL C N   1 
ATOM   10692 C CA  . VAL C 1 439 ? 35.496  35.124  -9.335  1.00 44.41  ? 439 VAL C CA  1 
ATOM   10693 C C   . VAL C 1 439 ? 35.919  34.496  -8.017  1.00 49.63  ? 439 VAL C C   1 
ATOM   10694 O O   . VAL C 1 439 ? 36.693  35.081  -7.271  1.00 47.97  ? 439 VAL C O   1 
ATOM   10695 C CB  . VAL C 1 439 ? 36.637  35.059  -10.363 1.00 47.78  ? 439 VAL C CB  1 
ATOM   10696 C CG1 . VAL C 1 439 ? 37.228  33.660  -10.449 1.00 49.92  ? 439 VAL C CG1 1 
ATOM   10697 C CG2 . VAL C 1 439 ? 36.191  35.558  -11.725 1.00 43.09  ? 439 VAL C CG2 1 
ATOM   10698 N N   . ALA C 1 440 ? 35.407  33.289  -7.747  1.00 52.96  ? 440 ALA C N   1 
ATOM   10699 C CA  . ALA C 1 440 ? 35.683  32.606  -6.494  1.00 52.37  ? 440 ALA C CA  1 
ATOM   10700 C C   . ALA C 1 440 ? 37.188  32.451  -6.319  1.00 59.96  ? 440 ALA C C   1 
ATOM   10701 O O   . ALA C 1 440 ? 37.866  32.036  -7.248  1.00 60.24  ? 440 ALA C O   1 
ATOM   10702 C CB  . ALA C 1 440 ? 35.002  31.252  -6.476  1.00 51.06  ? 440 ALA C CB  1 
ATOM   10703 N N   . GLY C 1 441 ? 37.688  32.811  -5.131  1.00 71.57  ? 441 GLY C N   1 
ATOM   10704 C CA  . GLY C 1 441 ? 39.041  32.485  -4.704  1.00 74.47  ? 441 GLY C CA  1 
ATOM   10705 C C   . GLY C 1 441 ? 40.121  33.411  -5.271  1.00 80.53  ? 441 GLY C C   1 
ATOM   10706 O O   . GLY C 1 441 ? 41.289  33.035  -5.278  1.00 87.52  ? 441 GLY C O   1 
ATOM   10707 N N   . SER C 1 442 ? 39.755  34.619  -5.720  1.00 76.73  ? 442 SER C N   1 
ATOM   10708 C CA  . SER C 1 442 ? 40.750  35.568  -6.205  1.00 89.15  ? 442 SER C CA  1 
ATOM   10709 C C   . SER C 1 442 ? 41.137  36.574  -5.108  1.00 87.16  ? 442 SER C C   1 
ATOM   10710 O O   . SER C 1 442 ? 40.224  37.183  -4.518  1.00 83.71  ? 442 SER C O   1 
ATOM   10711 C CB  . SER C 1 442 ? 40.295  36.255  -7.474  1.00 89.50  ? 442 SER C CB  1 
ATOM   10712 O OG  . SER C 1 442 ? 39.007  36.836  -7.334  1.00 84.92  ? 442 SER C OG  1 
HETATM 10713 O O1  . OAA D 2 .   ? -6.959  -27.098 -37.468 1.00 54.13  ? 501 OAA A O1  1 
HETATM 10714 O O2  . OAA D 2 .   ? -5.157  -28.291 -36.979 1.00 55.26  ? 501 OAA A O2  1 
HETATM 10715 O O4  . OAA D 2 .   ? -7.577  -23.238 -36.520 1.00 51.47  ? 501 OAA A O4  1 
HETATM 10716 O O5  . OAA D 2 .   ? -7.267  -24.893 -35.109 1.00 42.46  ? 501 OAA A O5  1 
HETATM 10717 O O3  . OAA D 2 .   ? -5.611  -24.230 -37.967 1.00 56.32  ? 501 OAA A O3  1 
HETATM 10718 C C1  . OAA D 2 .   ? -5.788  -27.208 -37.009 1.00 56.87  ? 501 OAA A C1  1 
HETATM 10719 C C2  . OAA D 2 .   ? -5.110  -25.950 -36.458 1.00 56.45  ? 501 OAA A C2  1 
HETATM 10720 C C3  . OAA D 2 .   ? -5.898  -24.730 -36.879 1.00 59.75  ? 501 OAA A C3  1 
HETATM 10721 C C4  . OAA D 2 .   ? -6.940  -24.264 -36.146 1.00 58.07  ? 501 OAA A C4  1 
HETATM 10722 N N1A . COA E 3 .   ? 8.989   -24.574 -43.078 1.00 69.74  ? 502 COA A N1A 1 
HETATM 10723 C C2A . COA E 3 .   ? 9.909   -25.548 -43.089 1.00 70.06  ? 502 COA A C2A 1 
HETATM 10724 N N3A . COA E 3 .   ? 9.736   -26.868 -43.045 1.00 70.25  ? 502 COA A N3A 1 
HETATM 10725 C C4A . COA E 3 .   ? 8.430   -27.190 -42.988 1.00 74.08  ? 502 COA A C4A 1 
HETATM 10726 C C5A . COA E 3 .   ? 7.370   -26.306 -42.969 1.00 74.48  ? 502 COA A C5A 1 
HETATM 10727 C C6A . COA E 3 .   ? 7.678   -24.930 -43.014 1.00 70.97  ? 502 COA A C6A 1 
HETATM 10728 N N6A . COA E 3 .   ? 6.751   -23.977 -42.987 1.00 66.07  ? 502 COA A N6A 1 
HETATM 10729 N N7A . COA E 3 .   ? 6.164   -26.995 -42.894 1.00 77.52  ? 502 COA A N7A 1 
HETATM 10730 C C8A . COA E 3 .   ? 6.505   -28.264 -42.877 1.00 77.18  ? 502 COA A C8A 1 
HETATM 10731 N N9A . COA E 3 .   ? 7.876   -28.446 -42.953 1.00 75.06  ? 502 COA A N9A 1 
HETATM 10732 C C1B . COA E 3 .   ? 8.599   -29.736 -42.932 1.00 73.35  ? 502 COA A C1B 1 
HETATM 10733 C C2B . COA E 3 .   ? 8.409   -30.503 -41.627 1.00 75.76  ? 502 COA A C2B 1 
HETATM 10734 O O2B . COA E 3 .   ? 9.204   -29.990 -40.582 1.00 72.46  ? 502 COA A O2B 1 
HETATM 10735 C C3B . COA E 3 .   ? 8.779   -31.923 -42.065 1.00 78.47  ? 502 COA A C3B 1 
HETATM 10736 O O3B . COA E 3 .   ? 10.191  -32.149 -42.092 1.00 91.71  ? 502 COA A O3B 1 
HETATM 10737 P P3B . COA E 3 .   ? 10.696  -33.383 -41.160 1.00 97.57  ? 502 COA A P3B 1 
HETATM 10738 O O7A . COA E 3 .   ? 10.277  -33.091 -39.725 1.00 89.72  ? 502 COA A O7A 1 
HETATM 10739 O O8A . COA E 3 .   ? 12.211  -33.434 -41.313 1.00 89.44  ? 502 COA A O8A 1 
HETATM 10740 O O9A . COA E 3 .   ? 10.017  -34.631 -41.707 1.00 104.36 ? 502 COA A O9A 1 
HETATM 10741 C C4B . COA E 3 .   ? 8.205   -31.979 -43.478 1.00 73.26  ? 502 COA A C4B 1 
HETATM 10742 O O4B . COA E 3 .   ? 8.079   -30.596 -43.922 1.00 72.94  ? 502 COA A O4B 1 
HETATM 10743 C C5B . COA E 3 .   ? 6.876   -32.689 -43.568 1.00 71.70  ? 502 COA A C5B 1 
HETATM 10744 O O5B . COA E 3 .   ? 5.946   -32.140 -42.588 1.00 72.14  ? 502 COA A O5B 1 
HETATM 10745 P P1A . COA E 3 .   ? 4.425   -31.840 -43.026 1.00 64.43  ? 502 COA A P1A 1 
HETATM 10746 O O1A . COA E 3 .   ? 3.667   -33.127 -43.100 1.00 73.47  ? 502 COA A O1A 1 
HETATM 10747 O O2A . COA E 3 .   ? 4.403   -31.007 -44.272 1.00 60.00  ? 502 COA A O2A 1 
HETATM 10748 O O3A . COA E 3 .   ? 3.951   -30.984 -41.739 1.00 61.76  ? 502 COA A O3A 1 
HETATM 10749 P P2A . COA E 3 .   ? 3.376   -31.363 -40.278 1.00 64.45  ? 502 COA A P2A 1 
HETATM 10750 O O4A . COA E 3 .   ? 1.933   -31.721 -40.441 1.00 70.51  ? 502 COA A O4A 1 
HETATM 10751 O O5A . COA E 3 .   ? 4.278   -32.308 -39.546 1.00 57.24  ? 502 COA A O5A 1 
HETATM 10752 O O6A . COA E 3 .   ? 3.489   -29.939 -39.543 1.00 63.56  ? 502 COA A O6A 1 
HETATM 10753 C CBP . COA E 3 .   ? 2.927   -27.609 -39.159 1.00 53.21  ? 502 COA A CBP 1 
HETATM 10754 C CCP . COA E 3 .   ? 2.429   -28.944 -39.715 1.00 55.94  ? 502 COA A CCP 1 
HETATM 10755 C CDP . COA E 3 .   ? 1.803   -26.569 -39.298 1.00 50.78  ? 502 COA A CDP 1 
HETATM 10756 C CEP . COA E 3 .   ? 3.258   -27.802 -37.669 1.00 55.40  ? 502 COA A CEP 1 
HETATM 10757 C CAP . COA E 3 .   ? 4.189   -27.157 -39.930 1.00 51.77  ? 502 COA A CAP 1 
HETATM 10758 O OAP . COA E 3 .   ? 3.819   -26.913 -41.310 1.00 48.16  ? 502 COA A OAP 1 
HETATM 10759 C C9P . COA E 3 .   ? 4.919   -25.952 -39.314 1.00 52.78  ? 502 COA A C9P 1 
HETATM 10760 O O9P . COA E 3 .   ? 5.777   -26.147 -38.451 1.00 45.69  ? 502 COA A O9P 1 
HETATM 10761 N N8P . COA E 3 .   ? 4.597   -24.725 -39.734 1.00 46.48  ? 502 COA A N8P 1 
HETATM 10762 C C7P . COA E 3 .   ? 5.180   -23.495 -39.196 1.00 50.53  ? 502 COA A C7P 1 
HETATM 10763 C C6P . COA E 3 .   ? 4.426   -22.969 -37.979 1.00 55.08  ? 502 COA A C6P 1 
HETATM 10764 C C5P . COA E 3 .   ? 2.983   -22.604 -38.292 1.00 54.29  ? 502 COA A C5P 1 
HETATM 10765 O O5P . COA E 3 .   ? 2.723   -21.751 -39.146 1.00 47.36  ? 502 COA A O5P 1 
HETATM 10766 N N4P . COA E 3 .   ? 2.021   -23.258 -37.612 1.00 57.41  ? 502 COA A N4P 1 
HETATM 10767 C C3P . COA E 3 .   ? 0.598   -22.930 -37.685 1.00 71.64  ? 502 COA A C3P 1 
HETATM 10768 C C2P . COA E 3 .   ? -0.288  -24.106 -38.095 1.00 79.55  ? 502 COA A C2P 1 
HETATM 10769 S S1P . COA E 3 .   ? -2.042  -23.674 -38.286 1.00 110.09 ? 502 COA A S1P 1 
HETATM 10770 O O1  . OAA F 2 .   ? -11.013 -44.357 -15.496 1.00 57.26  ? 501 OAA B O1  1 
HETATM 10771 O O2  . OAA F 2 .   ? -12.067 -46.031 -14.542 1.00 82.75  ? 501 OAA B O2  1 
HETATM 10772 O O4  . OAA F 2 .   ? -12.252 -46.342 -20.220 1.00 74.23  ? 501 OAA B O4  1 
HETATM 10773 O O5  . OAA F 2 .   ? -10.526 -47.352 -19.451 1.00 55.85  ? 501 OAA B O5  1 
HETATM 10774 O O3  . OAA F 2 .   ? -12.956 -45.615 -17.983 1.00 75.92  ? 501 OAA B O3  1 
HETATM 10775 C C1  . OAA F 2 .   ? -11.449 -45.537 -15.508 1.00 76.63  ? 501 OAA B C1  1 
HETATM 10776 C C2  . OAA F 2 .   ? -11.144 -46.443 -16.721 1.00 69.16  ? 501 OAA B C2  1 
HETATM 10777 C C3  . OAA F 2 .   ? -11.916 -46.255 -18.028 1.00 76.39  ? 501 OAA B C3  1 
HETATM 10778 C C4  . OAA F 2 .   ? -11.551 -46.686 -19.260 1.00 76.60  ? 501 OAA B C4  1 
HETATM 10779 N N1A . COA G 3 .   ? -31.321 -46.144 -24.389 1.00 124.48 ? 502 COA B N1A 1 
HETATM 10780 C C2A . COA G 3 .   ? -30.308 -45.749 -25.171 1.00 117.45 ? 502 COA B C2A 1 
HETATM 10781 N N3A . COA G 3 .   ? -29.006 -45.720 -24.900 1.00 116.86 ? 502 COA B N3A 1 
HETATM 10782 C C4A . COA G 3 .   ? -28.764 -46.159 -23.651 1.00 141.22 ? 502 COA B C4A 1 
HETATM 10783 C C5A . COA G 3 .   ? -29.691 -46.594 -22.730 1.00 143.83 ? 502 COA B C5A 1 
HETATM 10784 C C6A . COA G 3 .   ? -31.043 -46.583 -23.134 1.00 137.39 ? 502 COA B C6A 1 
HETATM 10785 N N6A . COA G 3 .   ? -32.049 -46.977 -22.357 1.00 131.38 ? 502 COA B N6A 1 
HETATM 10786 N N7A . COA G 3 .   ? -29.051 -46.967 -21.550 1.00 138.30 ? 502 COA B N7A 1 
HETATM 10787 C C8A . COA G 3 .   ? -27.773 -46.754 -21.773 1.00 138.29 ? 502 COA B C8A 1 
HETATM 10788 N N9A . COA G 3 .   ? -27.542 -46.270 -23.042 1.00 152.77 ? 502 COA B N9A 1 
HETATM 10789 C C1B . COA G 3 .   ? -26.294 -45.870 -23.678 1.00 160.87 ? 502 COA B C1B 1 
HETATM 10790 C C2B . COA G 3 .   ? -25.806 -44.470 -23.330 1.00 154.51 ? 502 COA B C2B 1 
HETATM 10791 O O2B . COA G 3 .   ? -26.664 -43.441 -23.777 1.00 142.37 ? 502 COA B O2B 1 
HETATM 10792 C C3B . COA G 3 .   ? -24.446 -44.534 -24.034 1.00 144.87 ? 502 COA B C3B 1 
HETATM 10793 O O3B . COA G 3 .   ? -24.606 -44.141 -25.420 1.00 115.12 ? 502 COA B O3B 1 
HETATM 10794 P P3B . COA G 3 .   ? -24.866 -45.062 -26.757 1.00 89.94  ? 502 COA B P3B 1 
HETATM 10795 O O7A . COA G 3 .   ? -25.285 -44.073 -27.828 1.00 87.14  ? 502 COA B O7A 1 
HETATM 10796 O O8A . COA G 3 .   ? -23.545 -45.741 -27.114 1.00 76.97  ? 502 COA B O8A 1 
HETATM 10797 O O9A . COA G 3 .   ? -25.972 -46.076 -26.489 1.00 104.93 ? 502 COA B O9A 1 
HETATM 10798 C C4B . COA G 3 .   ? -24.002 -45.982 -23.734 1.00 149.77 ? 502 COA B C4B 1 
HETATM 10799 O O4B . COA G 3 .   ? -25.207 -46.679 -23.297 1.00 159.89 ? 502 COA B O4B 1 
HETATM 10800 C C5B . COA G 3 .   ? -22.928 -46.106 -22.673 1.00 140.08 ? 502 COA B C5B 1 
HETATM 10801 O O5B . COA G 3 .   ? -21.673 -46.564 -23.266 1.00 127.03 ? 502 COA B O5B 1 
HETATM 10802 P P1A . COA G 3 .   ? -20.593 -47.327 -22.341 1.00 118.50 ? 502 COA B P1A 1 
HETATM 10803 O O1A . COA G 3 .   ? -20.578 -46.701 -20.984 1.00 121.95 ? 502 COA B O1A 1 
HETATM 10804 O O2A . COA G 3 .   ? -19.278 -47.415 -23.057 1.00 83.16  ? 502 COA B O2A 1 
HETATM 10805 O O3A . COA G 3 .   ? -21.239 -48.805 -22.194 1.00 122.57 ? 502 COA B O3A 1 
HETATM 10806 P P2A . COA G 3 .   ? -22.388 -49.711 -22.887 1.00 107.27 ? 502 COA B P2A 1 
HETATM 10807 O O4A . COA G 3 .   ? -23.732 -49.138 -22.576 1.00 93.08  ? 502 COA B O4A 1 
HETATM 10808 O O5A . COA G 3 .   ? -22.033 -49.945 -24.320 1.00 117.14 ? 502 COA B O5A 1 
HETATM 10809 O O6A . COA G 3 .   ? -22.256 -51.118 -22.115 1.00 104.58 ? 502 COA B O6A 1 
HETATM 10810 C CBP . COA G 3 .   ? -22.965 -53.474 -22.235 1.00 109.90 ? 502 COA B CBP 1 
HETATM 10811 C CCP . COA G 3 .   ? -22.098 -52.375 -22.861 1.00 109.81 ? 502 COA B CCP 1 
HETATM 10812 C CDP . COA G 3 .   ? -24.317 -53.529 -22.962 1.00 113.95 ? 502 COA B CDP 1 
HETATM 10813 C CEP . COA G 3 .   ? -22.263 -54.831 -22.407 1.00 102.61 ? 502 COA B CEP 1 
HETATM 10814 C CAP . COA G 3 .   ? -23.211 -53.205 -20.739 1.00 111.14 ? 502 COA B CAP 1 
HETATM 10815 O OAP . COA G 3 .   ? -24.070 -54.185 -20.167 1.00 99.53  ? 502 COA B OAP 1 
HETATM 10816 C C9P . COA G 3 .   ? -21.913 -53.116 -19.940 1.00 112.62 ? 502 COA B C9P 1 
HETATM 10817 O O9P . COA G 3 .   ? -21.344 -54.149 -19.585 1.00 108.96 ? 502 COA B O9P 1 
HETATM 10818 N N8P . COA G 3 .   ? -21.455 -51.891 -19.675 1.00 100.18 ? 502 COA B N8P 1 
HETATM 10819 C C7P . COA G 3 .   ? -20.229 -51.592 -18.944 1.00 84.57  ? 502 COA B C7P 1 
HETATM 10820 C C6P . COA G 3 .   ? -19.014 -51.557 -19.845 1.00 79.60  ? 502 COA B C6P 1 
HETATM 10821 C C5P . COA G 3 .   ? -17.990 -50.523 -19.438 1.00 74.48  ? 502 COA B C5P 1 
HETATM 10822 O O5P . COA G 3 .   ? -17.869 -49.486 -20.075 1.00 81.13  ? 502 COA B O5P 1 
HETATM 10823 N N4P . COA G 3 .   ? -17.220 -50.800 -18.385 1.00 81.35  ? 502 COA B N4P 1 
HETATM 10824 C C3P . COA G 3 .   ? -16.313 -49.851 -17.751 1.00 90.75  ? 502 COA B C3P 1 
HETATM 10825 C C2P . COA G 3 .   ? -14.910 -50.390 -17.621 1.00 90.73  ? 502 COA B C2P 1 
HETATM 10826 S S1P . COA G 3 .   ? -13.812 -49.236 -16.760 1.00 91.59  ? 502 COA B S1P 1 
HETATM 10827 O O1  . OAA H 2 .   ? 27.847  9.745   -3.384  1.00 54.48  ? 501 OAA C O1  1 
HETATM 10828 O O2  . OAA H 2 .   ? 28.696  8.545   -1.753  1.00 45.74  ? 501 OAA C O2  1 
HETATM 10829 O O4  . OAA H 2 .   ? 26.289  6.377   -1.396  1.00 44.55  ? 501 OAA C O4  1 
HETATM 10830 O O5  . OAA H 2 .   ? 27.720  4.689   -1.081  1.00 49.89  ? 501 OAA C O5  1 
HETATM 10831 O O3  . OAA H 2 .   ? 29.212  5.607   -3.002  1.00 48.26  ? 501 OAA C O3  1 
HETATM 10832 C C1  . OAA H 2 .   ? 28.119  8.653   -2.836  1.00 46.94  ? 501 OAA C C1  1 
HETATM 10833 C C2  . OAA H 2 .   ? 27.718  7.366   -3.541  1.00 52.94  ? 501 OAA C C2  1 
HETATM 10834 C C3  . OAA H 2 .   ? 28.144  6.164   -2.721  1.00 61.56  ? 501 OAA C C3  1 
HETATM 10835 C C4  . OAA H 2 .   ? 27.360  5.734   -1.694  1.00 66.52  ? 501 OAA C C4  1 
HETATM 10836 N N1A . COA I 3 .   ? 34.089  5.825   -17.695 1.00 46.23  ? 502 COA C N1A 1 
HETATM 10837 C C2A . COA I 3 .   ? 34.146  6.805   -18.604 1.00 46.68  ? 502 COA C C2A 1 
HETATM 10838 N N3A . COA I 3 .   ? 34.115  8.124   -18.434 1.00 44.85  ? 502 COA C N3A 1 
HETATM 10839 C C4A . COA I 3 .   ? 34.058  8.427   -17.129 1.00 45.84  ? 502 COA C C4A 1 
HETATM 10840 C C5A . COA I 3 .   ? 34.012  7.538   -16.080 1.00 49.75  ? 502 COA C C5A 1 
HETATM 10841 C C6A . COA I 3 .   ? 34.019  6.169   -16.387 1.00 45.78  ? 502 COA C C6A 1 
HETATM 10842 N N6A . COA I 3 .   ? 33.967  5.218   -15.460 1.00 46.79  ? 502 COA C N6A 1 
HETATM 10843 N N7A . COA I 3 .   ? 33.960  8.217   -14.873 1.00 51.44  ? 502 COA C N7A 1 
HETATM 10844 C C8A . COA I 3 .   ? 33.945  9.481   -15.214 1.00 49.26  ? 502 COA C C8A 1 
HETATM 10845 N N9A . COA I 3 .   ? 34.028  9.669   -16.558 1.00 45.65  ? 502 COA C N9A 1 
HETATM 10846 C C1B . COA I 3 .   ? 34.028  10.971  -17.251 1.00 47.93  ? 502 COA C C1B 1 
HETATM 10847 C C2B . COA I 3 .   ? 32.724  11.720  -17.016 1.00 54.55  ? 502 COA C C2B 1 
HETATM 10848 O O2B . COA I 3 .   ? 31.649  11.197  -17.763 1.00 53.27  ? 502 COA C O2B 1 
HETATM 10849 C C3B . COA I 3 .   ? 33.172  13.134  -17.395 1.00 53.09  ? 502 COA C C3B 1 
HETATM 10850 O O3B . COA I 3 .   ? 33.165  13.178  -18.813 1.00 67.97  ? 502 COA C O3B 1 
HETATM 10851 P P3B . COA I 3 .   ? 32.616  14.509  -19.536 1.00 67.31  ? 502 COA C P3B 1 
HETATM 10852 O O7A . COA I 3 .   ? 31.109  14.557  -19.393 1.00 62.34  ? 502 COA C O7A 1 
HETATM 10853 O O8A . COA I 3 .   ? 33.075  14.281  -20.969 1.00 69.97  ? 502 COA C O8A 1 
HETATM 10854 O O9A . COA I 3 .   ? 33.321  15.675  -18.860 1.00 65.06  ? 502 COA C O9A 1 
HETATM 10855 C C4B . COA I 3 .   ? 34.588  13.197  -16.807 1.00 52.03  ? 502 COA C C4B 1 
HETATM 10856 O O4B . COA I 3 .   ? 35.030  11.816  -16.715 1.00 47.75  ? 502 COA C O4B 1 
HETATM 10857 C C5B . COA I 3 .   ? 34.713  13.855  -15.448 1.00 51.44  ? 502 COA C C5B 1 
HETATM 10858 O O5B . COA I 3 .   ? 33.671  13.347  -14.531 1.00 48.11  ? 502 COA C O5B 1 
HETATM 10859 P P1A . COA I 3 .   ? 34.106  12.989  -13.036 1.00 49.79  ? 502 COA C P1A 1 
HETATM 10860 O O1A . COA I 3 .   ? 34.210  14.230  -12.214 1.00 54.99  ? 502 COA C O1A 1 
HETATM 10861 O O2A . COA I 3 .   ? 35.343  12.158  -13.027 1.00 46.30  ? 502 COA C O2A 1 
HETATM 10862 O O3A . COA I 3 .   ? 32.804  12.155  -12.625 1.00 51.46  ? 502 COA C O3A 1 
HETATM 10863 P P2A . COA I 3 .   ? 31.401  12.651  -12.021 1.00 50.31  ? 502 COA C P2A 1 
HETATM 10864 O O4A . COA I 3 .   ? 31.706  13.039  -10.614 1.00 47.41  ? 502 COA C O4A 1 
HETATM 10865 O O5A . COA I 3 .   ? 30.652  13.471  -13.015 1.00 48.65  ? 502 COA C O5A 1 
HETATM 10866 O O6A . COA I 3 .   ? 30.548  11.293  -12.045 1.00 49.19  ? 502 COA C O6A 1 
HETATM 10867 C CBP . COA I 3 .   ? 30.365  8.913   -11.684 1.00 44.88  ? 502 COA C CBP 1 
HETATM 10868 C CCP . COA I 3 .   ? 30.926  10.222  -11.130 1.00 46.96  ? 502 COA C CCP 1 
HETATM 10869 C CDP . COA I 3 .   ? 30.464  7.850   -10.581 1.00 41.84  ? 502 COA C CDP 1 
HETATM 10870 C CEP . COA I 3 .   ? 28.887  9.107   -12.067 1.00 44.93  ? 502 COA C CEP 1 
HETATM 10871 C CAP . COA I 3 .   ? 31.137  8.442   -12.930 1.00 40.56  ? 502 COA C CAP 1 
HETATM 10872 O OAP . COA I 3 .   ? 32.480  8.172   -12.541 1.00 39.35  ? 502 COA C OAP 1 
HETATM 10873 C C9P . COA I 3 .   ? 30.492  7.214   -13.565 1.00 39.81  ? 502 COA C C9P 1 
HETATM 10874 O O9P . COA I 3 .   ? 29.569  7.361   -14.350 1.00 40.88  ? 502 COA C O9P 1 
HETATM 10875 N N8P . COA I 3 .   ? 30.919  6.013   -13.207 1.00 41.11  ? 502 COA C N8P 1 
HETATM 10876 C C7P . COA I 3 .   ? 30.292  4.778   -13.683 1.00 38.74  ? 502 COA C C7P 1 
HETATM 10877 C C6P . COA I 3 .   ? 29.036  4.446   -12.910 1.00 37.32  ? 502 COA C C6P 1 
HETATM 10878 C C5P . COA I 3 .   ? 29.325  3.991   -11.494 1.00 37.45  ? 502 COA C C5P 1 
HETATM 10879 O O5P . COA I 3 .   ? 30.168  3.114   -11.296 1.00 37.59  ? 502 COA C O5P 1 
HETATM 10880 N N4P . COA I 3 .   ? 28.613  4.533   -10.477 1.00 41.85  ? 502 COA C N4P 1 
HETATM 10881 C C3P . COA I 3 .   ? 28.745  4.101   -9.081  1.00 42.93  ? 502 COA C C3P 1 
HETATM 10882 C C2P . COA I 3 .   ? 29.346  5.141   -8.143  1.00 54.21  ? 502 COA C C2P 1 
HETATM 10883 S S1P . COA I 3 .   ? 29.848  4.471   -6.522  1.00 75.92  ? 502 COA C S1P 1 
HETATM 10884 C C   . ACE J 4 .   ? 24.825  1.712   -6.676  1.00 45.73  ? 503 ACE C C   1 
HETATM 10885 O O   . ACE J 4 .   ? 24.550  2.591   -7.482  1.00 39.96  ? 503 ACE C O   1 
HETATM 10886 C CH3 . ACE J 4 .   ? 24.457  0.183   -6.857  1.00 35.42  ? 503 ACE C CH3 1 
HETATM 10887 O O   . HOH K 5 .   ? 6.901   -57.251 -26.355 1.00 41.97  ? 601 HOH A O   1 
HETATM 10888 O O   . HOH K 5 .   ? -32.595 -26.449 -42.394 1.00 53.69  ? 602 HOH A O   1 
HETATM 10889 O O   . HOH K 5 .   ? -25.837 -19.541 -9.113  1.00 45.86  ? 603 HOH A O   1 
HETATM 10890 O O   . HOH K 5 .   ? -0.285  -49.625 -45.838 1.00 46.58  ? 604 HOH A O   1 
HETATM 10891 O O   . HOH K 5 .   ? -14.875 -8.247  -4.704  1.00 38.25  ? 605 HOH A O   1 
HETATM 10892 O O   . HOH K 5 .   ? -20.307 -29.970 -15.327 1.00 32.59  ? 606 HOH A O   1 
HETATM 10893 O O   . HOH K 5 .   ? -19.657 -5.306  -40.290 1.00 33.59  ? 607 HOH A O   1 
HETATM 10894 O O   . HOH K 5 .   ? 4.647   -5.572  -27.688 1.00 43.63  ? 608 HOH A O   1 
HETATM 10895 O O   . HOH K 5 .   ? -18.614 2.866   -27.054 1.00 58.27  ? 609 HOH A O   1 
HETATM 10896 O O   . HOH K 5 .   ? -36.055 -37.210 -32.102 1.00 45.90  ? 610 HOH A O   1 
HETATM 10897 O O   . HOH K 5 .   ? -4.432  -15.050 -33.141 1.00 45.45  ? 611 HOH A O   1 
HETATM 10898 O O   . HOH K 5 .   ? 11.542  -4.915  -36.758 1.00 43.15  ? 612 HOH A O   1 
HETATM 10899 O O   . HOH K 5 .   ? 16.515  -9.064  -37.586 1.00 47.59  ? 613 HOH A O   1 
HETATM 10900 O O   . HOH K 5 .   ? -27.274 -40.106 -20.115 1.00 54.88  ? 614 HOH A O   1 
HETATM 10901 O O   . HOH K 5 .   ? 6.219   -18.734 -54.595 1.00 63.56  ? 615 HOH A O   1 
HETATM 10902 O O   . HOH K 5 .   ? -19.045 -29.323 -45.860 1.00 43.90  ? 616 HOH A O   1 
HETATM 10903 O O   . HOH K 5 .   ? -26.847 -14.446 -17.856 1.00 43.22  ? 617 HOH A O   1 
HETATM 10904 O O   . HOH K 5 .   ? -13.677 -21.159 -47.443 1.00 37.25  ? 618 HOH A O   1 
HETATM 10905 O O   . HOH K 5 .   ? -27.719 -51.944 -42.105 1.00 49.63  ? 619 HOH A O   1 
HETATM 10906 O O   . HOH K 5 .   ? 2.099   -10.858 -21.701 1.00 38.04  ? 620 HOH A O   1 
HETATM 10907 O O   . HOH K 5 .   ? -29.301 -39.785 -31.757 1.00 38.70  ? 621 HOH A O   1 
HETATM 10908 O O   . HOH K 5 .   ? -11.124 -16.293 -48.475 1.00 51.03  ? 622 HOH A O   1 
HETATM 10909 O O   . HOH K 5 .   ? -3.033  -13.070 -4.757  1.00 29.58  ? 623 HOH A O   1 
HETATM 10910 O O   . HOH K 5 .   ? -5.369  -46.309 -42.864 1.00 51.25  ? 624 HOH A O   1 
HETATM 10911 O O   . HOH K 5 .   ? -33.422 -20.043 -40.017 1.00 44.89  ? 625 HOH A O   1 
HETATM 10912 O O   . HOH K 5 .   ? 1.299   -27.553 -34.497 1.00 46.42  ? 626 HOH A O   1 
HETATM 10913 O O   . HOH K 5 .   ? 9.446   -16.075 -35.182 1.00 47.85  ? 627 HOH A O   1 
HETATM 10914 O O   . HOH K 5 .   ? -19.845 -25.418 -8.895  1.00 30.94  ? 628 HOH A O   1 
HETATM 10915 O O   . HOH K 5 .   ? 1.384   -2.987  -23.704 1.00 48.44  ? 629 HOH A O   1 
HETATM 10916 O O   . HOH K 5 .   ? -11.009 -58.361 -44.054 1.00 55.43  ? 630 HOH A O   1 
HETATM 10917 O O   . HOH K 5 .   ? 23.269  -16.377 -48.632 1.00 51.94  ? 631 HOH A O   1 
HETATM 10918 O O   . HOH K 5 .   ? 11.358  -10.337 -33.989 1.00 43.88  ? 632 HOH A O   1 
HETATM 10919 O O   . HOH K 5 .   ? -38.858 -31.358 -35.030 1.00 55.02  ? 633 HOH A O   1 
HETATM 10920 O O   . HOH K 5 .   ? -15.658 -40.167 -31.483 1.00 38.91  ? 634 HOH A O   1 
HETATM 10921 O O   . HOH K 5 .   ? -19.649 -8.899  -33.468 1.00 31.34  ? 635 HOH A O   1 
HETATM 10922 O O   . HOH K 5 .   ? 3.341   -42.937 -36.173 1.00 38.84  ? 636 HOH A O   1 
HETATM 10923 O O   . HOH K 5 .   ? -24.587 -20.423 -17.181 1.00 31.21  ? 637 HOH A O   1 
HETATM 10924 O O   . HOH K 5 .   ? -39.867 -24.635 -32.621 1.00 53.63  ? 638 HOH A O   1 
HETATM 10925 O O   . HOH K 5 .   ? -12.918 2.147   -25.207 1.00 30.51  ? 639 HOH A O   1 
HETATM 10926 O O   . HOH K 5 .   ? -25.190 -24.057 -11.239 1.00 45.99  ? 640 HOH A O   1 
HETATM 10927 O O   . HOH K 5 .   ? 0.030   -16.505 -25.961 1.00 44.30  ? 641 HOH A O   1 
HETATM 10928 O O   . HOH K 5 .   ? -0.909  -1.775  -27.149 1.00 43.55  ? 642 HOH A O   1 
HETATM 10929 O O   . HOH K 5 .   ? 5.377   -14.552 -29.018 1.00 51.71  ? 643 HOH A O   1 
HETATM 10930 O O   . HOH K 5 .   ? -20.280 -23.862 -51.011 1.00 51.51  ? 644 HOH A O   1 
HETATM 10931 O O   . HOH K 5 .   ? -12.431 -3.012  -19.932 1.00 29.96  ? 645 HOH A O   1 
HETATM 10932 O O   . HOH K 5 .   ? -11.877 -4.614  -17.839 1.00 29.19  ? 646 HOH A O   1 
HETATM 10933 O O   . HOH K 5 .   ? -16.410 -20.010 -52.779 1.00 51.71  ? 647 HOH A O   1 
HETATM 10934 O O   . HOH K 5 .   ? -27.121 -19.927 -13.841 1.00 44.30  ? 648 HOH A O   1 
HETATM 10935 O O   . HOH K 5 .   ? -17.865 3.279   -29.850 1.00 45.97  ? 649 HOH A O   1 
HETATM 10936 O O   . HOH K 5 .   ? 2.681   -13.647 -20.269 1.00 37.78  ? 650 HOH A O   1 
HETATM 10937 O O   . HOH K 5 .   ? -20.572 -7.997  -16.331 1.00 36.57  ? 651 HOH A O   1 
HETATM 10938 O O   . HOH K 5 .   ? -26.525 -38.124 -24.173 1.00 40.44  ? 652 HOH A O   1 
HETATM 10939 O O   . HOH K 5 .   ? -12.313 -48.336 -25.800 1.00 41.09  ? 653 HOH A O   1 
HETATM 10940 O O   . HOH K 5 .   ? -6.862  -53.486 -45.312 1.00 45.43  ? 654 HOH A O   1 
HETATM 10941 O O   . HOH K 5 .   ? -6.342  1.558   -33.100 1.00 44.73  ? 655 HOH A O   1 
HETATM 10942 O O   . HOH K 5 .   ? -3.532  -48.836 -33.888 1.00 37.37  ? 656 HOH A O   1 
HETATM 10943 O O   . HOH K 5 .   ? -20.632 -28.647 -42.101 1.00 48.86  ? 657 HOH A O   1 
HETATM 10944 O O   . HOH K 5 .   ? -29.578 -6.292  -31.195 1.00 44.10  ? 658 HOH A O   1 
HETATM 10945 O O   . HOH K 5 .   ? -12.198 -8.078  -7.231  1.00 39.87  ? 659 HOH A O   1 
HETATM 10946 O O   . HOH K 5 .   ? -27.050 -35.515 -24.321 1.00 39.59  ? 660 HOH A O   1 
HETATM 10947 O O   . HOH K 5 .   ? -4.290  -16.222 -36.493 1.00 41.15  ? 661 HOH A O   1 
HETATM 10948 O O   . HOH K 5 .   ? -32.095 -22.865 -23.706 1.00 39.81  ? 662 HOH A O   1 
HETATM 10949 O O   . HOH K 5 .   ? 0.593   -40.263 -30.860 1.00 40.56  ? 663 HOH A O   1 
HETATM 10950 O O   . HOH K 5 .   ? -18.017 1.844   -21.982 1.00 47.10  ? 664 HOH A O   1 
HETATM 10951 O O   . HOH K 5 .   ? -29.182 -18.044 -17.752 1.00 55.46  ? 665 HOH A O   1 
HETATM 10952 O O   . HOH K 5 .   ? -28.110 -21.538 -49.721 1.00 50.28  ? 666 HOH A O   1 
HETATM 10953 O O   . HOH K 5 .   ? -20.615 -36.697 -26.542 1.00 43.74  ? 667 HOH A O   1 
HETATM 10954 O O   . HOH K 5 .   ? -35.983 -35.949 -29.381 1.00 54.86  ? 668 HOH A O   1 
HETATM 10955 O O   . HOH K 5 .   ? -9.221  -11.221 -5.268  1.00 32.15  ? 669 HOH A O   1 
HETATM 10956 O O   . HOH K 5 .   ? -25.835 -25.749 -44.690 1.00 46.30  ? 670 HOH A O   1 
HETATM 10957 O O   . HOH K 5 .   ? -24.925 -51.346 -38.562 1.00 53.06  ? 671 HOH A O   1 
HETATM 10958 O O   . HOH K 5 .   ? 3.058   -11.573 -18.252 1.00 53.83  ? 672 HOH A O   1 
HETATM 10959 O O   . HOH K 5 .   ? 9.753   -27.858 -48.021 1.00 58.59  ? 673 HOH A O   1 
HETATM 10960 O O   . HOH K 5 .   ? -22.232 -1.545  -19.301 1.00 44.42  ? 674 HOH A O   1 
HETATM 10961 O O   . HOH K 5 .   ? -30.215 -27.132 -41.542 1.00 44.96  ? 675 HOH A O   1 
HETATM 10962 O O   . HOH K 5 .   ? -14.822 -43.583 -39.238 1.00 39.41  ? 676 HOH A O   1 
HETATM 10963 O O   . HOH K 5 .   ? -22.130 3.114   -28.984 1.00 52.27  ? 677 HOH A O   1 
HETATM 10964 O O   . HOH K 5 .   ? -18.876 -34.615 -26.812 1.00 29.00  ? 678 HOH A O   1 
HETATM 10965 O O   . HOH K 5 .   ? -14.587 -2.773  -43.502 1.00 44.52  ? 679 HOH A O   1 
HETATM 10966 O O   . HOH K 5 .   ? -7.339  -57.427 -42.092 1.00 41.70  ? 680 HOH A O   1 
HETATM 10967 O O   . HOH K 5 .   ? -16.347 3.511   -34.117 1.00 47.38  ? 681 HOH A O   1 
HETATM 10968 O O   . HOH K 5 .   ? -4.369  -22.008 -19.685 1.00 29.12  ? 682 HOH A O   1 
HETATM 10969 O O   . HOH K 5 .   ? -26.376 -30.491 -37.402 1.00 39.23  ? 683 HOH A O   1 
HETATM 10970 O O   . HOH K 5 .   ? -12.827 -25.976 -34.453 1.00 33.96  ? 684 HOH A O   1 
HETATM 10971 O O   . HOH K 5 .   ? -23.684 -12.142 -39.589 1.00 35.10  ? 685 HOH A O   1 
HETATM 10972 O O   . HOH K 5 .   ? -0.788  -11.160 -48.057 1.00 42.83  ? 686 HOH A O   1 
HETATM 10973 O O   . HOH K 5 .   ? -19.579 -29.082 -22.363 1.00 32.05  ? 687 HOH A O   1 
HETATM 10974 O O   . HOH K 5 .   ? 6.466   -9.975  -11.997 1.00 38.79  ? 688 HOH A O   1 
HETATM 10975 O O   . HOH K 5 .   ? 2.779   -16.691 -25.306 1.00 49.07  ? 689 HOH A O   1 
HETATM 10976 O O   . HOH K 5 .   ? -13.967 -6.351  -18.128 1.00 32.75  ? 690 HOH A O   1 
HETATM 10977 O O   . HOH K 5 .   ? -11.092 -21.117 -37.934 1.00 35.63  ? 691 HOH A O   1 
HETATM 10978 O O   . HOH K 5 .   ? -6.983  -33.293 -31.183 1.00 29.66  ? 692 HOH A O   1 
HETATM 10979 O O   . HOH K 5 .   ? 5.112   -0.865  -30.317 1.00 45.54  ? 693 HOH A O   1 
HETATM 10980 O O   . HOH K 5 .   ? -22.576 -13.858 -18.771 1.00 30.87  ? 694 HOH A O   1 
HETATM 10981 O O   . HOH K 5 .   ? -11.159 1.275   -13.736 1.00 37.41  ? 695 HOH A O   1 
HETATM 10982 O O   . HOH K 5 .   ? -30.063 -35.912 -14.928 1.00 41.76  ? 696 HOH A O   1 
HETATM 10983 O O   . HOH K 5 .   ? -2.888  -10.409 -6.891  1.00 40.76  ? 697 HOH A O   1 
HETATM 10984 O O   . HOH K 5 .   ? -18.394 -38.781 -28.556 1.00 41.67  ? 698 HOH A O   1 
HETATM 10985 O O   . HOH K 5 .   ? -1.438  1.952   -45.468 1.00 52.12  ? 699 HOH A O   1 
HETATM 10986 O O   . HOH K 5 .   ? -22.056 -38.508 -23.587 1.00 31.72  ? 700 HOH A O   1 
HETATM 10987 O O   . HOH K 5 .   ? 0.818   -13.284 -37.722 1.00 35.87  ? 701 HOH A O   1 
HETATM 10988 O O   . HOH K 5 .   ? -33.111 -28.237 -19.770 1.00 61.88  ? 702 HOH A O   1 
HETATM 10989 O O   . HOH K 5 .   ? -25.089 -41.263 -25.251 1.00 41.30  ? 703 HOH A O   1 
HETATM 10990 O O   . HOH K 5 .   ? -9.669  4.182   -29.858 1.00 53.07  ? 704 HOH A O   1 
HETATM 10991 O O   . HOH K 5 .   ? -25.292 -29.180 -42.322 1.00 50.04  ? 705 HOH A O   1 
HETATM 10992 O O   . HOH K 5 .   ? -0.786  -2.613  -16.780 1.00 43.57  ? 706 HOH A O   1 
HETATM 10993 O O   . HOH K 5 .   ? -9.320  -23.168 -44.202 1.00 39.62  ? 707 HOH A O   1 
HETATM 10994 O O   . HOH K 5 .   ? -3.634  -5.040  -10.766 1.00 23.80  ? 708 HOH A O   1 
HETATM 10995 O O   . HOH K 5 .   ? -18.533 -31.644 -33.152 1.00 45.96  ? 709 HOH A O   1 
HETATM 10996 O O   . HOH K 5 .   ? -11.086 3.425   -38.455 1.00 50.59  ? 710 HOH A O   1 
HETATM 10997 O O   . HOH K 5 .   ? -19.012 -0.232  -36.660 1.00 51.85  ? 711 HOH A O   1 
HETATM 10998 O O   . HOH K 5 .   ? -16.536 2.354   -18.624 1.00 48.28  ? 712 HOH A O   1 
HETATM 10999 O O   . HOH K 5 .   ? -15.634 -28.651 -29.980 1.00 37.07  ? 713 HOH A O   1 
HETATM 11000 O O   . HOH K 5 .   ? -4.708  -28.879 -33.380 1.00 45.44  ? 714 HOH A O   1 
HETATM 11001 O O   . HOH K 5 .   ? -23.067 -26.423 -20.344 1.00 29.66  ? 715 HOH A O   1 
HETATM 11002 O O   . HOH K 5 .   ? -32.216 -15.580 -33.476 1.00 47.67  ? 716 HOH A O   1 
HETATM 11003 O O   . HOH K 5 .   ? -30.404 -33.137 -25.866 1.00 39.48  ? 717 HOH A O   1 
HETATM 11004 O O   . HOH K 5 .   ? 6.430   -58.784 -33.768 1.00 41.61  ? 718 HOH A O   1 
HETATM 11005 O O   . HOH K 5 .   ? -4.850  -41.986 -42.108 1.00 61.25  ? 719 HOH A O   1 
HETATM 11006 O O   . HOH K 5 .   ? 2.737   -14.271 -45.897 1.00 43.05  ? 720 HOH A O   1 
HETATM 11007 O O   . HOH K 5 .   ? 7.475   -3.720  -35.404 1.00 50.66  ? 721 HOH A O   1 
HETATM 11008 O O   . HOH K 5 .   ? -31.984 -34.241 -28.021 1.00 42.16  ? 722 HOH A O   1 
HETATM 11009 O O   . HOH K 5 .   ? -7.812  -47.305 -45.085 1.00 51.75  ? 723 HOH A O   1 
HETATM 11010 O O   . HOH K 5 .   ? -33.348 -15.849 -24.451 1.00 61.19  ? 724 HOH A O   1 
HETATM 11011 O O   . HOH K 5 .   ? -23.173 -32.511 -41.988 1.00 37.94  ? 725 HOH A O   1 
HETATM 11012 O O   . HOH K 5 .   ? -20.886 -30.890 -34.649 1.00 45.97  ? 726 HOH A O   1 
HETATM 11013 O O   . HOH K 5 .   ? -12.180 -60.126 -42.685 1.00 58.73  ? 727 HOH A O   1 
HETATM 11014 O O   . HOH K 5 .   ? -18.992 -27.585 -43.940 1.00 39.01  ? 728 HOH A O   1 
HETATM 11015 O O   . HOH K 5 .   ? -6.101  -11.029 -13.817 1.00 34.39  ? 729 HOH A O   1 
HETATM 11016 O O   . HOH K 5 .   ? -16.135 -20.544 -8.456  1.00 29.20  ? 730 HOH A O   1 
HETATM 11017 O O   . HOH K 5 .   ? -1.866  -17.551 -11.382 1.00 27.05  ? 731 HOH A O   1 
HETATM 11018 O O   . HOH K 5 .   ? -6.477  2.556   -23.518 1.00 45.23  ? 732 HOH A O   1 
HETATM 11019 O O   . HOH K 5 .   ? 8.193   -9.567  -26.014 1.00 58.15  ? 733 HOH A O   1 
HETATM 11020 O O   . HOH K 5 .   ? -13.486 -4.303  -44.841 1.00 41.75  ? 734 HOH A O   1 
HETATM 11021 O O   . HOH K 5 .   ? -16.053 -32.164 -39.924 1.00 37.68  ? 735 HOH A O   1 
HETATM 11022 O O   . HOH K 5 .   ? 10.517  -9.795  -31.539 1.00 51.34  ? 736 HOH A O   1 
HETATM 11023 O O   . HOH K 5 .   ? -1.334  -50.984 -50.221 1.00 64.94  ? 737 HOH A O   1 
HETATM 11024 O O   . HOH K 5 .   ? -16.805 -35.358 -43.836 1.00 50.95  ? 738 HOH A O   1 
HETATM 11025 O O   . HOH K 5 .   ? -28.633 -7.933  -17.778 1.00 53.68  ? 739 HOH A O   1 
HETATM 11026 O O   . HOH K 5 .   ? -20.757 -7.959  -14.239 1.00 51.28  ? 740 HOH A O   1 
HETATM 11027 O O   . HOH K 5 .   ? -35.532 -31.718 -27.692 1.00 48.44  ? 741 HOH A O   1 
HETATM 11028 O O   . HOH K 5 .   ? -30.221 -21.011 -45.509 1.00 50.34  ? 742 HOH A O   1 
HETATM 11029 O O   . HOH K 5 .   ? 4.579   -60.730 -34.313 1.00 47.19  ? 743 HOH A O   1 
HETATM 11030 O O   . HOH K 5 .   ? 3.062   -10.293 -24.579 1.00 36.18  ? 744 HOH A O   1 
HETATM 11031 O O   . HOH K 5 .   ? -15.781 -4.686  -18.507 1.00 40.95  ? 745 HOH A O   1 
HETATM 11032 O O   . HOH K 5 .   ? -2.535  -26.488 -34.089 1.00 45.25  ? 746 HOH A O   1 
HETATM 11033 O O   . HOH K 5 .   ? -1.836  -18.310 -33.414 1.00 37.42  ? 747 HOH A O   1 
HETATM 11034 O O   . HOH K 5 .   ? -22.461 -31.305 -15.357 1.00 37.25  ? 748 HOH A O   1 
HETATM 11035 O O   . HOH K 5 .   ? -2.366  -16.306 -31.061 1.00 44.10  ? 749 HOH A O   1 
HETATM 11036 O O   . HOH K 5 .   ? 1.202   -11.509 -39.786 1.00 35.00  ? 750 HOH A O   1 
HETATM 11037 O O   . HOH K 5 .   ? 3.559   -13.911 -43.599 1.00 40.25  ? 751 HOH A O   1 
HETATM 11038 O O   . HOH K 5 .   ? 1.748   -8.331  -17.418 1.00 44.05  ? 752 HOH A O   1 
HETATM 11039 O O   . HOH K 5 .   ? 6.079   -0.902  -35.165 1.00 50.54  ? 753 HOH A O   1 
HETATM 11040 O O   . HOH K 5 .   ? 21.895  -8.282  -51.697 1.00 60.29  ? 754 HOH A O   1 
HETATM 11041 O O   . HOH K 5 .   ? -2.366  0.929   -28.418 1.00 50.05  ? 755 HOH A O   1 
HETATM 11042 O O   . HOH K 5 .   ? 21.648  -8.530  -49.287 1.00 65.37  ? 756 HOH A O   1 
HETATM 11043 O O   . HOH K 5 .   ? -3.303  -59.531 -29.493 1.00 51.88  ? 757 HOH A O   1 
HETATM 11044 O O   . HOH K 5 .   ? -21.872 -42.613 -22.797 1.00 39.76  ? 758 HOH A O   1 
HETATM 11045 O O   . HOH K 5 .   ? -2.995  -6.191  -8.466  1.00 36.85  ? 759 HOH A O   1 
HETATM 11046 O O   . HOH K 5 .   ? -13.902 5.671   -36.378 1.00 51.28  ? 760 HOH A O   1 
HETATM 11047 O O   . HOH K 5 .   ? -7.795  -6.963  -5.359  1.00 38.78  ? 761 HOH A O   1 
HETATM 11048 O O   . HOH K 5 .   ? -8.913  2.480   -32.050 1.00 35.03  ? 762 HOH A O   1 
HETATM 11049 O O   . HOH K 5 .   ? -0.354  -9.234  -8.604  1.00 11.09  ? 763 HOH A O   1 
HETATM 11050 O O   . HOH K 5 .   ? -27.910 -41.970 -31.288 1.00 49.20  ? 764 HOH A O   1 
HETATM 11051 O O   . HOH K 5 .   ? -34.470 -52.625 -32.821 1.00 54.30  ? 765 HOH A O   1 
HETATM 11052 O O   . HOH K 5 .   ? -12.840 -33.376 -45.617 1.00 54.44  ? 766 HOH A O   1 
HETATM 11053 O O   . HOH K 5 .   ? -23.597 -32.074 -12.674 1.00 47.21  ? 767 HOH A O   1 
HETATM 11054 O O   . HOH K 5 .   ? -23.742 -40.426 -22.930 1.00 36.81  ? 768 HOH A O   1 
HETATM 11055 O O   . HOH K 5 .   ? -11.076 -3.375  -10.932 1.00 62.08  ? 769 HOH A O   1 
HETATM 11056 O O   . HOH K 5 .   ? -34.648 -51.429 -35.215 1.00 50.08  ? 770 HOH A O   1 
HETATM 11057 O O   . HOH K 5 .   ? -13.087 -13.468 -48.703 1.00 36.21  ? 771 HOH A O   1 
HETATM 11058 O O   . HOH K 5 .   ? 11.795  -14.449 -35.845 1.00 44.54  ? 772 HOH A O   1 
HETATM 11059 O O   . HOH K 5 .   ? 13.168  -8.365  -34.509 1.00 46.15  ? 773 HOH A O   1 
HETATM 11060 O O   . HOH K 5 .   ? 6.817   -16.343 -30.087 1.00 58.13  ? 774 HOH A O   1 
HETATM 11061 O O   . HOH K 5 .   ? 3.837   -7.745  -24.990 1.00 52.07  ? 775 HOH A O   1 
HETATM 11062 O O   . HOH K 5 .   ? -10.173 -8.529  -5.512  1.00 45.62  ? 776 HOH A O   1 
HETATM 11063 O O   . HOH K 5 .   ? -15.617 -0.795  -45.401 1.00 64.32  ? 777 HOH A O   1 
HETATM 11064 O O   . HOH K 5 .   ? -5.202  3.178   -30.910 1.00 54.13  ? 778 HOH A O   1 
HETATM 11065 O O   . HOH K 5 .   ? -34.397 -33.935 -28.865 1.00 52.76  ? 779 HOH A O   1 
HETATM 11066 O O   . HOH K 5 .   ? -19.722 -29.093 -48.302 1.00 49.54  ? 780 HOH A O   1 
HETATM 11067 O O   . HOH K 5 .   ? -32.273 -5.337  -31.456 1.00 60.34  ? 781 HOH A O   1 
HETATM 11068 O O   . HOH K 5 .   ? -4.940  2.450   -28.121 1.00 65.18  ? 782 HOH A O   1 
HETATM 11069 O O   . HOH K 5 .   ? 3.757   -9.020  -19.492 1.00 56.37  ? 783 HOH A O   1 
HETATM 11070 O O   . HOH K 5 .   ? 15.829  -9.253  -34.954 1.00 55.38  ? 784 HOH A O   1 
HETATM 11071 O O   . HOH K 5 .   ? -7.133  -12.140 -3.459  1.00 50.19  ? 785 HOH A O   1 
HETATM 11072 O O   . HOH K 5 .   ? -21.604 -0.456  -16.661 1.00 64.94  ? 786 HOH A O   1 
HETATM 11073 O O   . HOH K 5 .   ? -36.486 -52.466 -31.063 1.00 55.60  ? 787 HOH A O   1 
HETATM 11074 O O   . HOH L 5 .   ? -12.969 -41.740 -4.837  1.00 38.64  ? 601 HOH B O   1 
HETATM 11075 O O   . HOH L 5 .   ? -13.105 -55.560 -42.494 1.00 46.07  ? 602 HOH B O   1 
HETATM 11076 O O   . HOH L 5 .   ? -22.357 -36.724 3.492   1.00 42.66  ? 603 HOH B O   1 
HETATM 11077 O O   . HOH L 5 .   ? -6.327  -52.650 -50.756 1.00 60.83  ? 604 HOH B O   1 
HETATM 11078 O O   . HOH L 5 .   ? 10.582  -52.171 -4.697  1.00 50.25  ? 605 HOH B O   1 
HETATM 11079 O O   . HOH L 5 .   ? 16.013  -48.499 -11.086 1.00 49.40  ? 606 HOH B O   1 
HETATM 11080 O O   . HOH L 5 .   ? -31.449 -57.733 -17.697 1.00 58.73  ? 607 HOH B O   1 
HETATM 11081 O O   . HOH L 5 .   ? 10.426  -42.913 -36.775 1.00 49.63  ? 608 HOH B O   1 
HETATM 11082 O O   . HOH L 5 .   ? 17.829  -41.363 -28.011 1.00 44.90  ? 609 HOH B O   1 
HETATM 11083 O O   . HOH L 5 .   ? -28.698 -44.014 -0.920  1.00 40.35  ? 610 HOH B O   1 
HETATM 11084 O O   . HOH L 5 .   ? -18.259 -50.218 -35.495 1.00 58.75  ? 611 HOH B O   1 
HETATM 11085 O O   . HOH L 5 .   ? -17.977 -35.285 -7.010  1.00 39.59  ? 612 HOH B O   1 
HETATM 11086 O O   . HOH L 5 .   ? 4.935   -45.403 9.543   1.00 42.86  ? 613 HOH B O   1 
HETATM 11087 O O   . HOH L 5 .   ? 7.859   -18.344 -10.339 1.00 45.14  ? 614 HOH B O   1 
HETATM 11088 O O   . HOH L 5 .   ? -16.893 -35.982 7.512   1.00 49.19  ? 615 HOH B O   1 
HETATM 11089 O O   . HOH L 5 .   ? 5.469   -52.793 -41.693 1.00 39.94  ? 616 HOH B O   1 
HETATM 11090 O O   . HOH L 5 .   ? -19.943 -30.889 -1.729  1.00 38.10  ? 617 HOH B O   1 
HETATM 11091 O O   . HOH L 5 .   ? -13.058 -46.035 -6.545  1.00 36.45  ? 618 HOH B O   1 
HETATM 11092 O O   . HOH L 5 .   ? -19.977 -47.316 8.435   1.00 42.21  ? 619 HOH B O   1 
HETATM 11093 O O   . HOH L 5 .   ? -2.169  -51.839 7.181   1.00 46.31  ? 620 HOH B O   1 
HETATM 11094 O O   . HOH L 5 .   ? -13.075 -52.462 -36.151 1.00 49.76  ? 621 HOH B O   1 
HETATM 11095 O O   . HOH L 5 .   ? -23.188 -54.851 -17.361 1.00 53.17  ? 622 HOH B O   1 
HETATM 11096 O O   . HOH L 5 .   ? -24.396 -21.333 -0.949  1.00 35.99  ? 623 HOH B O   1 
HETATM 11097 O O   . HOH L 5 .   ? 10.980  -41.332 -30.625 1.00 35.29  ? 624 HOH B O   1 
HETATM 11098 O O   . HOH L 5 .   ? -17.852 -48.590 -12.054 1.00 51.81  ? 625 HOH B O   1 
HETATM 11099 O O   . HOH L 5 .   ? 6.715   -35.076 -31.935 1.00 41.59  ? 626 HOH B O   1 
HETATM 11100 O O   . HOH L 5 .   ? -28.948 -46.449 4.804   1.00 48.67  ? 627 HOH B O   1 
HETATM 11101 O O   . HOH L 5 .   ? -2.531  -61.899 -12.619 1.00 49.69  ? 628 HOH B O   1 
HETATM 11102 O O   . HOH L 5 .   ? -6.201  -61.518 -20.152 1.00 55.88  ? 629 HOH B O   1 
HETATM 11103 O O   . HOH L 5 .   ? 2.204   -24.613 -20.912 1.00 29.14  ? 630 HOH B O   1 
HETATM 11104 O O   . HOH L 5 .   ? 11.391  -27.225 -27.224 1.00 51.72  ? 631 HOH B O   1 
HETATM 11105 O O   . HOH L 5 .   ? -14.410 -57.437 -12.789 1.00 36.54  ? 632 HOH B O   1 
HETATM 11106 O O   . HOH L 5 .   ? -5.856  -35.577 -38.963 1.00 42.65  ? 633 HOH B O   1 
HETATM 11107 O O   . HOH L 5 .   ? -22.067 -59.914 4.840   1.00 43.60  ? 634 HOH B O   1 
HETATM 11108 O O   . HOH L 5 .   ? 4.409   -27.993 7.623   1.00 42.40  ? 635 HOH B O   1 
HETATM 11109 O O   . HOH L 5 .   ? 20.746  -43.777 -22.729 1.00 53.55  ? 636 HOH B O   1 
HETATM 11110 O O   . HOH L 5 .   ? -3.070  -13.823 1.029   1.00 37.70  ? 637 HOH B O   1 
HETATM 11111 O O   . HOH L 5 .   ? -6.227  -47.654 -11.487 1.00 43.27  ? 638 HOH B O   1 
HETATM 11112 O O   . HOH L 5 .   ? -4.930  -33.707 11.591  1.00 37.64  ? 639 HOH B O   1 
HETATM 11113 O O   . HOH L 5 .   ? -21.353 -35.828 -6.494  1.00 57.26  ? 640 HOH B O   1 
HETATM 11114 O O   . HOH L 5 .   ? -10.550 -46.864 -12.610 1.00 48.65  ? 641 HOH B O   1 
HETATM 11115 O O   . HOH L 5 .   ? 1.823   -18.113 -16.010 1.00 25.99  ? 642 HOH B O   1 
HETATM 11116 O O   . HOH L 5 .   ? -3.074  -51.392 -23.554 1.00 41.67  ? 643 HOH B O   1 
HETATM 11117 O O   . HOH L 5 .   ? 9.062   -22.802 -10.791 1.00 38.46  ? 644 HOH B O   1 
HETATM 11118 O O   . HOH L 5 .   ? 16.011  -22.234 -21.076 1.00 57.28  ? 645 HOH B O   1 
HETATM 11119 O O   . HOH L 5 .   ? 19.460  -38.378 -21.161 1.00 48.98  ? 646 HOH B O   1 
HETATM 11120 O O   . HOH L 5 .   ? -5.504  -28.719 6.282   1.00 25.64  ? 647 HOH B O   1 
HETATM 11121 O O   . HOH L 5 .   ? 0.254   -30.487 10.950  1.00 40.16  ? 648 HOH B O   1 
HETATM 11122 O O   . HOH L 5 .   ? -15.836 -42.992 -11.656 1.00 45.04  ? 649 HOH B O   1 
HETATM 11123 O O   . HOH L 5 .   ? -17.916 -47.333 -3.655  1.00 31.22  ? 650 HOH B O   1 
HETATM 11124 O O   . HOH L 5 .   ? 2.689   -48.754 4.514   1.00 34.53  ? 651 HOH B O   1 
HETATM 11125 O O   . HOH L 5 .   ? -15.023 -13.899 -3.957  1.00 30.10  ? 652 HOH B O   1 
HETATM 11126 O O   . HOH L 5 .   ? 8.521   -46.542 -21.256 1.00 36.12  ? 653 HOH B O   1 
HETATM 11127 O O   . HOH L 5 .   ? 8.737   -59.306 -2.032  1.00 55.44  ? 654 HOH B O   1 
HETATM 11128 O O   . HOH L 5 .   ? 12.284  -35.075 -24.066 1.00 33.94  ? 655 HOH B O   1 
HETATM 11129 O O   . HOH L 5 .   ? -16.989 -63.020 3.248   1.00 49.46  ? 656 HOH B O   1 
HETATM 11130 O O   . HOH L 5 .   ? -13.507 -28.959 -12.739 1.00 25.92  ? 657 HOH B O   1 
HETATM 11131 O O   . HOH L 5 .   ? -3.408  -53.573 5.434   1.00 50.08  ? 658 HOH B O   1 
HETATM 11132 O O   . HOH L 5 .   ? -33.824 -47.420 0.848   1.00 47.94  ? 659 HOH B O   1 
HETATM 11133 O O   . HOH L 5 .   ? 5.806   -42.312 6.330   1.00 44.11  ? 660 HOH B O   1 
HETATM 11134 O O   . HOH L 5 .   ? -18.436 -62.537 0.191   1.00 43.08  ? 661 HOH B O   1 
HETATM 11135 O O   . HOH L 5 .   ? 9.393   -29.533 -31.227 1.00 55.41  ? 662 HOH B O   1 
HETATM 11136 O O   . HOH L 5 .   ? -15.807 -43.424 -8.923  1.00 40.10  ? 663 HOH B O   1 
HETATM 11137 O O   . HOH L 5 .   ? 2.228   -42.161 0.587   1.00 37.04  ? 664 HOH B O   1 
HETATM 11138 O O   . HOH L 5 .   ? 10.934  -58.422 -11.367 1.00 56.32  ? 665 HOH B O   1 
HETATM 11139 O O   . HOH L 5 .   ? -8.247  -61.297 1.619   1.00 52.66  ? 666 HOH B O   1 
HETATM 11140 O O   . HOH L 5 .   ? 0.517   -38.061 -29.525 1.00 36.80  ? 667 HOH B O   1 
HETATM 11141 O O   . HOH L 5 .   ? 1.865   -55.009 -19.391 1.00 47.41  ? 668 HOH B O   1 
HETATM 11142 O O   . HOH L 5 .   ? 11.886  -24.077 -26.864 1.00 42.26  ? 669 HOH B O   1 
HETATM 11143 O O   . HOH L 5 .   ? -22.991 -38.943 -5.176  1.00 45.14  ? 670 HOH B O   1 
HETATM 11144 O O   . HOH L 5 .   ? -35.692 -58.305 -1.875  1.00 57.08  ? 671 HOH B O   1 
HETATM 11145 O O   . HOH L 5 .   ? 0.743   -36.251 -25.240 1.00 31.90  ? 672 HOH B O   1 
HETATM 11146 O O   . HOH L 5 .   ? -23.086 -39.573 8.627   1.00 52.66  ? 673 HOH B O   1 
HETATM 11147 O O   . HOH L 5 .   ? -19.339 -55.830 -3.601  1.00 38.29  ? 674 HOH B O   1 
HETATM 11148 O O   . HOH L 5 .   ? -8.708  -14.297 -2.085  1.00 33.40  ? 675 HOH B O   1 
HETATM 11149 O O   . HOH L 5 .   ? 3.378   -22.886 1.052   1.00 62.72  ? 676 HOH B O   1 
HETATM 11150 O O   . HOH L 5 .   ? 6.572   -26.195 -11.259 1.00 32.54  ? 677 HOH B O   1 
HETATM 11151 O O   . HOH L 5 .   ? 1.638   -31.678 -19.819 1.00 28.87  ? 678 HOH B O   1 
HETATM 11152 O O   . HOH L 5 .   ? -29.146 -55.417 -16.787 1.00 55.06  ? 679 HOH B O   1 
HETATM 11153 O O   . HOH L 5 .   ? -5.141  -55.432 -33.217 1.00 46.75  ? 680 HOH B O   1 
HETATM 11154 O O   . HOH L 5 .   ? -6.038  -26.719 4.716   1.00 30.35  ? 681 HOH B O   1 
HETATM 11155 O O   . HOH L 5 .   ? 14.305  -32.953 -14.034 1.00 43.65  ? 682 HOH B O   1 
HETATM 11156 O O   . HOH L 5 .   ? -20.859 -33.934 -1.097  1.00 42.04  ? 683 HOH B O   1 
HETATM 11157 O O   . HOH L 5 .   ? -5.390  -43.737 -16.418 1.00 27.94  ? 684 HOH B O   1 
HETATM 11158 O O   . HOH L 5 .   ? 2.220   -49.613 -46.564 1.00 57.42  ? 685 HOH B O   1 
HETATM 11159 O O   . HOH L 5 .   ? -28.185 -55.761 10.138  1.00 49.19  ? 686 HOH B O   1 
HETATM 11160 O O   . HOH L 5 .   ? -22.438 -52.827 -5.619  1.00 40.86  ? 687 HOH B O   1 
HETATM 11161 O O   . HOH L 5 .   ? -25.164 -44.882 5.521   1.00 47.95  ? 688 HOH B O   1 
HETATM 11162 O O   . HOH L 5 .   ? 2.683   -51.179 -18.822 1.00 44.91  ? 689 HOH B O   1 
HETATM 11163 O O   . HOH L 5 .   ? -8.039  -54.015 -13.335 1.00 43.77  ? 690 HOH B O   1 
HETATM 11164 O O   . HOH L 5 .   ? 2.607   -25.351 1.020   1.00 44.90  ? 691 HOH B O   1 
HETATM 11165 O O   . HOH L 5 .   ? -14.010 -24.005 12.576  1.00 44.34  ? 692 HOH B O   1 
HETATM 11166 O O   . HOH L 5 .   ? -17.207 -25.744 6.689   1.00 41.87  ? 693 HOH B O   1 
HETATM 11167 O O   . HOH L 5 .   ? -7.459  -47.601 -22.874 1.00 42.60  ? 694 HOH B O   1 
HETATM 11168 O O   . HOH L 5 .   ? 5.096   -29.521 -17.156 1.00 26.45  ? 695 HOH B O   1 
HETATM 11169 O O   . HOH L 5 .   ? -26.961 -45.239 -6.605  1.00 44.70  ? 696 HOH B O   1 
HETATM 11170 O O   . HOH L 5 .   ? -2.036  -49.002 -22.563 1.00 44.16  ? 697 HOH B O   1 
HETATM 11171 O O   . HOH L 5 .   ? -11.087 -40.495 -23.824 1.00 30.33  ? 698 HOH B O   1 
HETATM 11172 O O   . HOH L 5 .   ? -5.980  -16.413 0.908   1.00 49.65  ? 699 HOH B O   1 
HETATM 11173 O O   . HOH L 5 .   ? 4.833   -51.412 -22.912 1.00 34.99  ? 700 HOH B O   1 
HETATM 11174 O O   . HOH L 5 .   ? 8.880   -33.589 -26.502 1.00 37.61  ? 701 HOH B O   1 
HETATM 11175 O O   . HOH L 5 .   ? 9.296   -37.645 -32.675 1.00 53.14  ? 702 HOH B O   1 
HETATM 11176 O O   . HOH L 5 .   ? -15.869 -57.424 -0.727  1.00 34.79  ? 703 HOH B O   1 
HETATM 11177 O O   . HOH L 5 .   ? 12.540  -50.600 -17.760 1.00 47.63  ? 704 HOH B O   1 
HETATM 11178 O O   . HOH L 5 .   ? -18.942 -41.585 -13.222 1.00 46.42  ? 705 HOH B O   1 
HETATM 11179 O O   . HOH L 5 .   ? 7.499   -15.779 -7.651  1.00 41.20  ? 706 HOH B O   1 
HETATM 11180 O O   . HOH L 5 .   ? -2.606  -40.796 -30.771 1.00 39.87  ? 707 HOH B O   1 
HETATM 11181 O O   . HOH L 5 .   ? 4.751   -27.758 -4.662  1.00 31.12  ? 708 HOH B O   1 
HETATM 11182 O O   . HOH L 5 .   ? 3.808   -33.156 -29.336 1.00 31.00  ? 709 HOH B O   1 
HETATM 11183 O O   . HOH L 5 .   ? -19.040 -40.099 -30.761 1.00 47.36  ? 710 HOH B O   1 
HETATM 11184 O O   . HOH L 5 .   ? 8.333   -33.681 -29.016 1.00 43.67  ? 711 HOH B O   1 
HETATM 11185 O O   . HOH L 5 .   ? -4.023  -26.994 2.884   1.00 29.88  ? 712 HOH B O   1 
HETATM 11186 O O   . HOH L 5 .   ? 8.288   -54.428 -40.595 1.00 41.15  ? 713 HOH B O   1 
HETATM 11187 O O   . HOH L 5 .   ? -3.004  -56.857 -11.060 1.00 33.00  ? 714 HOH B O   1 
HETATM 11188 O O   . HOH L 5 .   ? -5.066  -56.495 -37.920 1.00 44.56  ? 715 HOH B O   1 
HETATM 11189 O O   . HOH L 5 .   ? -14.392 -19.798 4.093   1.00 28.59  ? 716 HOH B O   1 
HETATM 11190 O O   . HOH L 5 .   ? -21.930 -45.409 -33.111 1.00 42.67  ? 717 HOH B O   1 
HETATM 11191 O O   . HOH L 5 .   ? -5.131  -57.816 -6.072  1.00 42.64  ? 718 HOH B O   1 
HETATM 11192 O O   . HOH L 5 .   ? -9.726  -53.115 -15.263 1.00 31.85  ? 719 HOH B O   1 
HETATM 11193 O O   . HOH L 5 .   ? -37.092 -49.965 6.260   1.00 60.75  ? 720 HOH B O   1 
HETATM 11194 O O   . HOH L 5 .   ? -18.276 -49.253 -1.822  1.00 33.86  ? 721 HOH B O   1 
HETATM 11195 O O   . HOH L 5 .   ? -12.037 -60.788 8.833   1.00 43.41  ? 722 HOH B O   1 
HETATM 11196 O O   . HOH L 5 .   ? -6.812  -22.348 10.436  1.00 35.79  ? 723 HOH B O   1 
HETATM 11197 O O   . HOH L 5 .   ? -2.598  -39.363 -19.148 1.00 38.55  ? 724 HOH B O   1 
HETATM 11198 O O   . HOH L 5 .   ? -1.416  -27.318 11.578  1.00 53.31  ? 725 HOH B O   1 
HETATM 11199 O O   . HOH L 5 .   ? 6.544   -48.114 -2.598  1.00 37.47  ? 726 HOH B O   1 
HETATM 11200 O O   . HOH L 5 .   ? -30.330 -63.188 -20.672 1.00 43.74  ? 727 HOH B O   1 
HETATM 11201 O O   . HOH L 5 .   ? -22.062 -25.183 -6.933  1.00 45.89  ? 728 HOH B O   1 
HETATM 11202 O O   . HOH L 5 .   ? 11.055  -26.169 -9.073  1.00 44.64  ? 729 HOH B O   1 
HETATM 11203 O O   . HOH L 5 .   ? 15.892  -44.593 -33.636 1.00 51.90  ? 730 HOH B O   1 
HETATM 11204 O O   . HOH L 5 .   ? 2.810   -20.632 -21.529 1.00 45.37  ? 731 HOH B O   1 
HETATM 11205 O O   . HOH L 5 .   ? -20.652 -29.218 -4.520  1.00 46.47  ? 732 HOH B O   1 
HETATM 11206 O O   . HOH L 5 .   ? -11.887 -22.858 -1.772  1.00 33.78  ? 733 HOH B O   1 
HETATM 11207 O O   . HOH L 5 .   ? -24.531 -55.435 -13.156 1.00 49.07  ? 734 HOH B O   1 
HETATM 11208 O O   . HOH L 5 .   ? -16.007 -40.219 -6.818  1.00 35.10  ? 735 HOH B O   1 
HETATM 11209 O O   . HOH L 5 .   ? -16.020 -21.823 5.040   1.00 28.90  ? 736 HOH B O   1 
HETATM 11210 O O   . HOH L 5 .   ? 1.434   -53.129 -17.586 1.00 39.63  ? 737 HOH B O   1 
HETATM 11211 O O   . HOH L 5 .   ? -0.579  -41.562 -26.914 1.00 44.66  ? 738 HOH B O   1 
HETATM 11212 O O   . HOH L 5 .   ? -17.133 -55.027 -13.565 1.00 41.24  ? 739 HOH B O   1 
HETATM 11213 O O   . HOH L 5 .   ? 17.507  -37.109 -22.623 1.00 44.47  ? 740 HOH B O   1 
HETATM 11214 O O   . HOH L 5 .   ? 4.353   -24.636 -22.408 1.00 37.77  ? 741 HOH B O   1 
HETATM 11215 O O   . HOH L 5 .   ? 0.602   -42.578 -22.166 1.00 40.19  ? 742 HOH B O   1 
HETATM 11216 O O   . HOH L 5 .   ? -1.752  -53.075 -25.453 1.00 49.78  ? 743 HOH B O   1 
HETATM 11217 O O   . HOH L 5 .   ? 8.106   -21.846 -7.832  1.00 51.63  ? 744 HOH B O   1 
HETATM 11218 O O   . HOH L 5 .   ? 3.535   -32.408 -33.532 1.00 34.84  ? 745 HOH B O   1 
HETATM 11219 O O   . HOH L 5 .   ? -3.784  -11.498 -1.268  1.00 48.63  ? 746 HOH B O   1 
HETATM 11220 O O   . HOH L 5 .   ? 17.688  -49.069 -0.690  1.00 48.89  ? 747 HOH B O   1 
HETATM 11221 O O   . HOH L 5 .   ? 13.167  -54.041 -11.474 1.00 52.19  ? 748 HOH B O   1 
HETATM 11222 O O   . HOH L 5 .   ? -14.512 -54.277 -17.241 1.00 51.94  ? 749 HOH B O   1 
HETATM 11223 O O   . HOH L 5 .   ? 2.869   -29.942 10.900  1.00 51.40  ? 750 HOH B O   1 
HETATM 11224 O O   . HOH L 5 .   ? -15.013 -53.922 12.285  1.00 54.61  ? 751 HOH B O   1 
HETATM 11225 O O   . HOH L 5 .   ? -1.964  -27.116 4.534   1.00 37.11  ? 752 HOH B O   1 
HETATM 11226 O O   . HOH L 5 .   ? -21.658 -46.918 -10.196 1.00 51.93  ? 753 HOH B O   1 
HETATM 11227 O O   . HOH L 5 .   ? 2.750   -43.869 -21.309 1.00 49.90  ? 754 HOH B O   1 
HETATM 11228 O O   . HOH L 5 .   ? -10.316 -14.409 2.214   1.00 43.95  ? 755 HOH B O   1 
HETATM 11229 O O   . HOH L 5 .   ? -33.988 -49.309 -11.142 1.00 68.20  ? 756 HOH B O   1 
HETATM 11230 O O   . HOH L 5 .   ? -15.109 -17.467 2.865   1.00 32.12  ? 757 HOH B O   1 
HETATM 11231 O O   . HOH L 5 .   ? -11.330 -54.821 -37.067 1.00 53.58  ? 758 HOH B O   1 
HETATM 11232 O O   . HOH L 5 .   ? -21.257 -47.722 -18.218 1.00 69.25  ? 759 HOH B O   1 
HETATM 11233 O O   . HOH L 5 .   ? -12.806 -63.716 -10.360 1.00 48.36  ? 760 HOH B O   1 
HETATM 11234 O O   . HOH L 5 .   ? 5.562   -36.858 -36.297 1.00 51.82  ? 761 HOH B O   1 
HETATM 11235 O O   . HOH L 5 .   ? 4.666   -36.042 2.101   1.00 56.46  ? 762 HOH B O   1 
HETATM 11236 O O   . HOH L 5 .   ? -20.512 -53.522 -3.825  1.00 37.34  ? 763 HOH B O   1 
HETATM 11237 O O   . HOH L 5 .   ? -24.440 -65.270 -18.417 1.00 65.77  ? 764 HOH B O   1 
HETATM 11238 O O   . HOH L 5 .   ? -3.689  -57.676 -3.229  1.00 39.68  ? 765 HOH B O   1 
HETATM 11239 O O   . HOH L 5 .   ? -12.431 -52.949 -13.928 1.00 48.24  ? 766 HOH B O   1 
HETATM 11240 O O   . HOH L 5 .   ? -13.832 -42.589 -19.134 1.00 43.87  ? 767 HOH B O   1 
HETATM 11241 O O   . HOH L 5 .   ? 3.372   -52.988 -20.965 1.00 47.81  ? 768 HOH B O   1 
HETATM 11242 O O   . HOH L 5 .   ? -24.771 -21.933 -5.959  1.00 58.57  ? 769 HOH B O   1 
HETATM 11243 O O   . HOH L 5 .   ? -26.116 -36.149 -0.510  1.00 58.40  ? 770 HOH B O   1 
HETATM 11244 O O   . HOH L 5 .   ? -22.444 -50.877 -13.051 1.00 55.66  ? 771 HOH B O   1 
HETATM 11245 O O   . HOH L 5 .   ? 6.119   -26.176 -5.613  1.00 51.42  ? 772 HOH B O   1 
HETATM 11246 O O   . HOH L 5 .   ? -17.697 -17.697 0.000   0.50 13.04  ? 773 HOH B O   1 
HETATM 11247 O O   . HOH L 5 .   ? -19.979 -48.679 -11.712 1.00 51.36  ? 774 HOH B O   1 
HETATM 11248 O O   . HOH L 5 .   ? 5.553   -32.611 -31.183 1.00 33.65  ? 775 HOH B O   1 
HETATM 11249 O O   . HOH L 5 .   ? -16.648 -51.934 12.520  1.00 55.13  ? 776 HOH B O   1 
HETATM 11250 O O   . HOH L 5 .   ? 3.603   -19.333 -19.276 1.00 35.40  ? 777 HOH B O   1 
HETATM 11251 O O   . HOH L 5 .   ? -4.391  -54.488 -23.797 1.00 56.81  ? 778 HOH B O   1 
HETATM 11252 O O   . HOH L 5 .   ? -24.258 -40.964 -7.059  1.00 57.71  ? 779 HOH B O   1 
HETATM 11253 O O   . HOH L 5 .   ? -29.927 -43.958 -3.189  1.00 51.66  ? 780 HOH B O   1 
HETATM 11254 O O   . HOH L 5 .   ? -28.918 -46.102 -5.288  1.00 57.25  ? 781 HOH B O   1 
HETATM 11255 O O   . HOH L 5 .   ? 10.474  -27.323 -29.890 1.00 53.45  ? 782 HOH B O   1 
HETATM 11256 O O   . HOH L 5 .   ? 5.148   -22.225 -23.056 1.00 53.48  ? 783 HOH B O   1 
HETATM 11257 O O   . HOH L 5 .   ? 6.975   -36.414 -35.613 1.00 43.50  ? 784 HOH B O   1 
HETATM 11258 O O   . HOH L 5 .   ? -27.850 -37.331 0.947   1.00 63.18  ? 785 HOH B O   1 
HETATM 11259 O O   . HOH L 5 .   ? 4.350   -16.536 -19.026 1.00 48.20  ? 786 HOH B O   1 
HETATM 11260 O O   . HOH L 5 .   ? -15.088 -37.219 -44.636 1.00 49.26  ? 787 HOH B O   1 
HETATM 11261 O O   . HOH L 5 .   ? -24.382 -56.614 -15.843 1.00 53.67  ? 788 HOH B O   1 
HETATM 11262 O O   . HOH L 5 .   ? -30.559 -46.370 6.893   1.00 53.99  ? 789 HOH B O   1 
HETATM 11263 O O   . HOH L 5 .   ? 16.002  -24.256 -20.786 1.00 61.22  ? 790 HOH B O   1 
HETATM 11264 O O   . HOH L 5 .   ? -26.381 -41.979 -6.883  1.00 62.24  ? 791 HOH B O   1 
HETATM 11265 O O   . HOH L 5 .   ? 16.158  -38.204 -24.891 1.00 47.33  ? 792 HOH B O   1 
HETATM 11266 O O   . HOH L 5 .   ? -21.536 -30.506 -43.717 1.00 53.88  ? 793 HOH B O   1 
HETATM 11267 O O   . HOH L 5 .   ? -5.891  -59.938 -7.353  1.00 49.27  ? 794 HOH B O   1 
HETATM 11268 O O   . HOH L 5 .   ? -8.244  -14.147 0.611   1.00 48.56  ? 795 HOH B O   1 
HETATM 11269 O O   . HOH L 5 .   ? -10.715 -12.492 -2.846  1.00 48.78  ? 796 HOH B O   1 
HETATM 11270 O O   . HOH L 5 .   ? 3.038   -16.293 5.029   1.00 61.45  ? 797 HOH B O   1 
HETATM 11271 O O   . HOH L 5 .   ? -4.250  -58.139 -33.534 1.00 60.68  ? 798 HOH B O   1 
HETATM 11272 O O   . HOH M 5 .   ? 48.024  -10.747 -21.902 1.00 56.49  ? 601 HOH C O   1 
HETATM 11273 O O   . HOH M 5 .   ? 36.583  10.974  10.210  1.00 42.22  ? 602 HOH C O   1 
HETATM 11274 O O   . HOH M 5 .   ? 24.134  28.128  19.843  1.00 42.00  ? 603 HOH C O   1 
HETATM 11275 O O   . HOH M 5 .   ? 30.045  -16.446 -25.773 1.00 48.00  ? 604 HOH C O   1 
HETATM 11276 O O   . HOH M 5 .   ? 42.236  2.716   -1.261  1.00 53.52  ? 605 HOH C O   1 
HETATM 11277 O O   . HOH M 5 .   ? 20.761  -21.431 9.438   1.00 52.02  ? 606 HOH C O   1 
HETATM 11278 O O   . HOH M 5 .   ? 30.463  2.295   24.743  1.00 42.44  ? 607 HOH C O   1 
HETATM 11279 O O   . HOH M 5 .   ? 8.105   0.175   20.235  1.00 41.70  ? 608 HOH C O   1 
HETATM 11280 O O   . HOH M 5 .   ? 21.742  -11.556 20.972  1.00 44.13  ? 609 HOH C O   1 
HETATM 11281 O O   . HOH M 5 .   ? 6.193   11.977  11.252  1.00 33.93  ? 610 HOH C O   1 
HETATM 11282 O O   . HOH M 5 .   ? 43.736  -10.767 -12.141 1.00 53.41  ? 611 HOH C O   1 
HETATM 11283 O O   . HOH M 5 .   ? 15.962  -20.566 4.389   1.00 29.13  ? 612 HOH C O   1 
HETATM 11284 O O   . HOH M 5 .   ? 14.889  -15.490 -10.117 1.00 50.50  ? 613 HOH C O   1 
HETATM 11285 O O   . HOH M 5 .   ? 11.355  -4.801  -11.457 1.00 39.16  ? 614 HOH C O   1 
HETATM 11286 O O   . HOH M 5 .   ? 16.366  23.166  16.002  1.00 40.50  ? 615 HOH C O   1 
HETATM 11287 O O   . HOH M 5 .   ? 35.479  -13.883 5.137   1.00 39.94  ? 616 HOH C O   1 
HETATM 11288 O O   . HOH M 5 .   ? 16.990  30.007  3.046   1.00 46.05  ? 617 HOH C O   1 
HETATM 11289 O O   . HOH M 5 .   ? 1.932   -14.187 2.621   1.00 69.00  ? 618 HOH C O   1 
HETATM 11290 O O   . HOH M 5 .   ? -3.777  -7.002  0.398   1.00 30.88  ? 619 HOH C O   1 
HETATM 11291 O O   . HOH M 5 .   ? 24.245  -3.225  -4.230  1.00 38.67  ? 620 HOH C O   1 
HETATM 11292 O O   . HOH M 5 .   ? 36.338  4.852   20.014  1.00 57.23  ? 621 HOH C O   1 
HETATM 11293 O O   . HOH M 5 .   ? 41.638  5.121   12.039  1.00 51.54  ? 622 HOH C O   1 
HETATM 11294 O O   . HOH M 5 .   ? 27.301  -2.247  -4.353  1.00 32.58  ? 623 HOH C O   1 
HETATM 11295 O O   . HOH M 5 .   ? 26.275  24.951  24.930  1.00 47.87  ? 624 HOH C O   1 
HETATM 11296 O O   . HOH M 5 .   ? 10.147  -16.737 13.755  1.00 41.21  ? 625 HOH C O   1 
HETATM 11297 O O   . HOH M 5 .   ? 22.581  21.834  20.099  1.00 43.00  ? 626 HOH C O   1 
HETATM 11298 O O   . HOH M 5 .   ? 40.230  -2.174  20.080  1.00 54.43  ? 627 HOH C O   1 
HETATM 11299 O O   . HOH M 5 .   ? 42.342  3.561   1.244   1.00 53.92  ? 628 HOH C O   1 
HETATM 11300 O O   . HOH M 5 .   ? 7.984   2.380   15.670  1.00 28.57  ? 629 HOH C O   1 
HETATM 11301 O O   . HOH M 5 .   ? 22.997  6.698   31.041  1.00 47.53  ? 630 HOH C O   1 
HETATM 11302 O O   . HOH M 5 .   ? 8.469   -3.633  17.984  1.00 46.17  ? 631 HOH C O   1 
HETATM 11303 O O   . HOH M 5 .   ? 16.955  26.516  9.015   1.00 38.67  ? 632 HOH C O   1 
HETATM 11304 O O   . HOH M 5 .   ? -5.259  -4.258  6.032   1.00 28.54  ? 633 HOH C O   1 
HETATM 11305 O O   . HOH M 5 .   ? 28.541  19.586  -10.582 1.00 43.46  ? 634 HOH C O   1 
HETATM 11306 O O   . HOH M 5 .   ? -4.468  -10.116 5.944   1.00 41.90  ? 635 HOH C O   1 
HETATM 11307 O O   . HOH M 5 .   ? 18.068  -16.954 -7.469  1.00 38.96  ? 636 HOH C O   1 
HETATM 11308 O O   . HOH M 5 .   ? 32.114  9.163   21.324  1.00 40.22  ? 637 HOH C O   1 
HETATM 11309 O O   . HOH M 5 .   ? 30.717  -13.181 11.396  1.00 30.46  ? 638 HOH C O   1 
HETATM 11310 O O   . HOH M 5 .   ? 4.488   2.012   18.094  1.00 39.35  ? 639 HOH C O   1 
HETATM 11311 O O   . HOH M 5 .   ? 42.793  6.278   10.293  1.00 43.31  ? 640 HOH C O   1 
HETATM 11312 O O   . HOH M 5 .   ? 12.622  -7.502  -10.857 1.00 40.89  ? 641 HOH C O   1 
HETATM 11313 O O   . HOH M 5 .   ? 12.735  -13.294 15.932  1.00 47.24  ? 642 HOH C O   1 
HETATM 11314 O O   . HOH M 5 .   ? -0.319  7.073   10.639  1.00 25.52  ? 643 HOH C O   1 
HETATM 11315 O O   . HOH M 5 .   ? -0.338  1.870   16.777  1.00 45.30  ? 644 HOH C O   1 
HETATM 11316 O O   . HOH M 5 .   ? 30.086  -6.203  15.187  1.00 28.99  ? 645 HOH C O   1 
HETATM 11317 O O   . HOH M 5 .   ? 27.773  -14.053 -19.966 1.00 41.88  ? 646 HOH C O   1 
HETATM 11318 O O   . HOH M 5 .   ? 18.547  -13.215 -13.106 1.00 40.10  ? 647 HOH C O   1 
HETATM 11319 O O   . HOH M 5 .   ? 43.536  11.538  3.843   1.00 53.59  ? 648 HOH C O   1 
HETATM 11320 O O   . HOH M 5 .   ? 28.882  2.659   2.421   1.00 30.01  ? 649 HOH C O   1 
HETATM 11321 O O   . HOH M 5 .   ? 22.135  21.807  -9.766  1.00 49.15  ? 650 HOH C O   1 
HETATM 11322 O O   . HOH M 5 .   ? 8.590   -13.615 3.233   1.00 28.08  ? 651 HOH C O   1 
HETATM 11323 O O   . HOH M 5 .   ? 36.784  34.640  -2.623  1.00 51.91  ? 652 HOH C O   1 
HETATM 11324 O O   . HOH M 5 .   ? 22.303  14.894  -1.994  1.00 27.34  ? 653 HOH C O   1 
HETATM 11325 O O   . HOH M 5 .   ? 14.593  5.050   23.325  1.00 41.29  ? 654 HOH C O   1 
HETATM 11326 O O   . HOH M 5 .   ? 24.093  -9.290  11.157  1.00 29.24  ? 655 HOH C O   1 
HETATM 11327 O O   . HOH M 5 .   ? 12.570  -20.250 9.367   1.00 53.08  ? 656 HOH C O   1 
HETATM 11328 O O   . HOH M 5 .   ? 40.702  3.757   4.308   1.00 46.58  ? 657 HOH C O   1 
HETATM 11329 O O   . HOH M 5 .   ? 25.775  9.025   -10.014 1.00 41.94  ? 658 HOH C O   1 
HETATM 11330 O O   . HOH M 5 .   ? 10.665  -15.176 3.880   1.00 26.60  ? 659 HOH C O   1 
HETATM 11331 O O   . HOH M 5 .   ? 2.141   5.323   16.361  1.00 52.31  ? 660 HOH C O   1 
HETATM 11332 O O   . HOH M 5 .   ? 40.761  8.687   12.371  1.00 47.50  ? 661 HOH C O   1 
HETATM 11333 O O   . HOH M 5 .   ? 13.933  30.689  -7.196  1.00 41.75  ? 662 HOH C O   1 
HETATM 11334 O O   . HOH M 5 .   ? 41.732  -12.511 -13.775 1.00 38.61  ? 663 HOH C O   1 
HETATM 11335 O O   . HOH M 5 .   ? 14.483  1.699   -9.381  1.00 43.07  ? 664 HOH C O   1 
HETATM 11336 O O   . HOH M 5 .   ? 5.494   17.911  20.877  1.00 42.95  ? 665 HOH C O   1 
HETATM 11337 O O   . HOH M 5 .   ? 36.951  -4.442  -11.214 1.00 35.24  ? 666 HOH C O   1 
HETATM 11338 O O   . HOH M 5 .   ? 24.866  -8.746  -19.882 1.00 38.31  ? 667 HOH C O   1 
HETATM 11339 O O   . HOH M 5 .   ? 16.146  -1.479  -11.366 1.00 42.83  ? 668 HOH C O   1 
HETATM 11340 O O   . HOH M 5 .   ? 31.506  -12.957 18.428  1.00 56.10  ? 669 HOH C O   1 
HETATM 11341 O O   . HOH M 5 .   ? 26.065  -2.601  -18.135 1.00 41.01  ? 670 HOH C O   1 
HETATM 11342 O O   . HOH M 5 .   ? 33.644  -11.725 17.879  1.00 42.40  ? 671 HOH C O   1 
HETATM 11343 O O   . HOH M 5 .   ? 35.294  -16.639 14.881  1.00 50.70  ? 672 HOH C O   1 
HETATM 11344 O O   . HOH M 5 .   ? 20.869  10.417  6.576   1.00 34.85  ? 673 HOH C O   1 
HETATM 11345 O O   . HOH M 5 .   ? 30.244  25.281  5.588   1.00 35.95  ? 674 HOH C O   1 
HETATM 11346 O O   . HOH M 5 .   ? 32.984  14.340  14.446  1.00 38.46  ? 675 HOH C O   1 
HETATM 11347 O O   . HOH M 5 .   ? 10.892  22.536  18.132  1.00 50.71  ? 676 HOH C O   1 
HETATM 11348 O O   . HOH M 5 .   ? 20.047  12.153  28.533  1.00 46.01  ? 677 HOH C O   1 
HETATM 11349 O O   . HOH M 5 .   ? 24.870  -21.785 7.985   1.00 43.95  ? 678 HOH C O   1 
HETATM 11350 O O   . HOH M 5 .   ? 39.228  -2.212  2.926   1.00 34.47  ? 679 HOH C O   1 
HETATM 11351 O O   . HOH M 5 .   ? 28.631  -5.305  -9.468  1.00 27.50  ? 680 HOH C O   1 
HETATM 11352 O O   . HOH M 5 .   ? 25.370  7.650   4.007   1.00 33.37  ? 681 HOH C O   1 
HETATM 11353 O O   . HOH M 5 .   ? 4.465   -9.877  18.235  1.00 52.68  ? 682 HOH C O   1 
HETATM 11354 O O   . HOH M 5 .   ? 29.587  9.797   -15.565 1.00 55.01  ? 683 HOH C O   1 
HETATM 11355 O O   . HOH M 5 .   ? 35.174  7.594   17.457  1.00 41.67  ? 684 HOH C O   1 
HETATM 11356 O O   . HOH M 5 .   ? 15.171  17.564  17.730  1.00 33.16  ? 685 HOH C O   1 
HETATM 11357 O O   . HOH M 5 .   ? 26.493  -17.406 -14.486 1.00 56.09  ? 686 HOH C O   1 
HETATM 11358 O O   . HOH M 5 .   ? 15.529  -11.304 21.598  1.00 55.21  ? 687 HOH C O   1 
HETATM 11359 O O   . HOH M 5 .   ? 28.259  12.494  17.652  1.00 35.53  ? 688 HOH C O   1 
HETATM 11360 O O   . HOH M 5 .   ? 31.184  -0.981  -22.795 1.00 44.29  ? 689 HOH C O   1 
HETATM 11361 O O   . HOH M 5 .   ? 2.985   -0.335  17.475  1.00 47.55  ? 690 HOH C O   1 
HETATM 11362 O O   . HOH M 5 .   ? 27.497  24.074  -12.467 1.00 40.73  ? 691 HOH C O   1 
HETATM 11363 O O   . HOH M 5 .   ? -1.717  -10.050 3.257   1.00 41.64  ? 692 HOH C O   1 
HETATM 11364 O O   . HOH M 5 .   ? 3.267   -8.373  -15.409 1.00 35.02  ? 693 HOH C O   1 
HETATM 11365 O O   . HOH M 5 .   ? 43.960  3.895   -5.611  1.00 50.62  ? 694 HOH C O   1 
HETATM 11366 O O   . HOH M 5 .   ? 21.229  -17.828 -13.676 1.00 54.60  ? 695 HOH C O   1 
HETATM 11367 O O   . HOH M 5 .   ? 29.071  -17.285 -11.097 1.00 49.47  ? 696 HOH C O   1 
HETATM 11368 O O   . HOH M 5 .   ? 37.058  4.902   -5.952  1.00 41.93  ? 697 HOH C O   1 
HETATM 11369 O O   . HOH M 5 .   ? 38.320  2.568   5.271   1.00 34.36  ? 698 HOH C O   1 
HETATM 11370 O O   . HOH M 5 .   ? 14.487  20.554  12.708  1.00 29.81  ? 699 HOH C O   1 
HETATM 11371 O O   . HOH M 5 .   ? 34.304  9.278   -20.920 1.00 50.73  ? 700 HOH C O   1 
HETATM 11372 O O   . HOH M 5 .   ? 37.859  -18.259 -19.943 1.00 53.42  ? 701 HOH C O   1 
HETATM 11373 O O   . HOH M 5 .   ? 33.325  7.889   -22.910 1.00 46.77  ? 702 HOH C O   1 
HETATM 11374 O O   . HOH M 5 .   ? 40.257  2.664   19.688  1.00 50.53  ? 703 HOH C O   1 
HETATM 11375 O O   . HOH M 5 .   ? 9.483   -4.177  13.801  1.00 28.74  ? 704 HOH C O   1 
HETATM 11376 O O   . HOH M 5 .   ? 38.936  8.932   -18.456 1.00 53.88  ? 705 HOH C O   1 
HETATM 11377 O O   . HOH M 5 .   ? 17.761  16.383  9.921   1.00 33.57  ? 706 HOH C O   1 
HETATM 11378 O O   . HOH M 5 .   ? 28.252  -10.043 -25.141 1.00 45.61  ? 707 HOH C O   1 
HETATM 11379 O O   . HOH M 5 .   ? 29.157  32.991  15.133  1.00 58.54  ? 708 HOH C O   1 
HETATM 11380 O O   . HOH M 5 .   ? 35.856  -10.025 16.214  1.00 46.39  ? 709 HOH C O   1 
HETATM 11381 O O   . HOH M 5 .   ? 13.242  10.899  10.671  1.00 28.06  ? 710 HOH C O   1 
HETATM 11382 O O   . HOH M 5 .   ? 4.653   -7.287  -2.722  1.00 30.56  ? 711 HOH C O   1 
HETATM 11383 O O   . HOH M 5 .   ? 23.592  4.294   -9.840  1.00 48.85  ? 712 HOH C O   1 
HETATM 11384 O O   . HOH M 5 .   ? -2.043  -7.952  -6.011  1.00 41.87  ? 713 HOH C O   1 
HETATM 11385 O O   . HOH M 5 .   ? 4.476   -19.572 2.523   1.00 35.15  ? 714 HOH C O   1 
HETATM 11386 O O   . HOH M 5 .   ? 8.727   -11.779 5.249   1.00 29.27  ? 715 HOH C O   1 
HETATM 11387 O O   . HOH M 5 .   ? 36.575  -20.674 -6.496  1.00 45.69  ? 716 HOH C O   1 
HETATM 11388 O O   . HOH M 5 .   ? 15.587  -22.149 -0.278  1.00 61.44  ? 717 HOH C O   1 
HETATM 11389 O O   . HOH M 5 .   ? -0.624  2.356   7.049   1.00 27.18  ? 718 HOH C O   1 
HETATM 11390 O O   . HOH M 5 .   ? 34.743  9.106   10.356  1.00 29.45  ? 719 HOH C O   1 
HETATM 11391 O O   . HOH M 5 .   ? 34.952  4.673   0.524   1.00 30.69  ? 720 HOH C O   1 
HETATM 11392 O O   . HOH M 5 .   ? 14.700  2.395   22.751  1.00 51.47  ? 721 HOH C O   1 
HETATM 11393 O O   . HOH M 5 .   ? 3.785   -14.174 -6.690  1.00 27.16  ? 722 HOH C O   1 
HETATM 11394 O O   . HOH M 5 .   ? 22.376  21.864  6.617   1.00 38.03  ? 723 HOH C O   1 
HETATM 11395 O O   . HOH M 5 .   ? 16.594  15.118  21.329  1.00 36.26  ? 724 HOH C O   1 
HETATM 11396 O O   . HOH M 5 .   ? 24.090  13.587  9.640   1.00 36.97  ? 725 HOH C O   1 
HETATM 11397 O O   . HOH M 5 .   ? 32.867  -19.673 -12.803 1.00 48.13  ? 726 HOH C O   1 
HETATM 11398 O O   . HOH M 5 .   ? 26.682  -15.621 16.544  1.00 45.66  ? 727 HOH C O   1 
HETATM 11399 O O   . HOH M 5 .   ? 6.978   -10.027 11.737  1.00 40.37  ? 728 HOH C O   1 
HETATM 11400 O O   . HOH M 5 .   ? 33.645  -2.987  -14.048 1.00 34.85  ? 729 HOH C O   1 
HETATM 11401 O O   . HOH M 5 .   ? 42.338  -12.891 -9.123  1.00 52.40  ? 730 HOH C O   1 
HETATM 11402 O O   . HOH M 5 .   ? 17.625  -11.214 13.712  1.00 55.08  ? 731 HOH C O   1 
HETATM 11403 O O   . HOH M 5 .   ? 45.218  -10.157 -9.909  1.00 51.85  ? 732 HOH C O   1 
HETATM 11404 O O   . HOH M 5 .   ? 29.925  8.743   -6.701  1.00 48.12  ? 733 HOH C O   1 
HETATM 11405 O O   . HOH M 5 .   ? 6.267   13.489  13.394  1.00 33.14  ? 734 HOH C O   1 
HETATM 11406 O O   . HOH M 5 .   ? 38.833  -7.651  -7.580  1.00 33.34  ? 735 HOH C O   1 
HETATM 11407 O O   . HOH M 5 .   ? 29.899  -14.581 -10.117 1.00 40.99  ? 736 HOH C O   1 
HETATM 11408 O O   . HOH M 5 .   ? 10.687  3.578   -4.553  1.00 27.58  ? 737 HOH C O   1 
HETATM 11409 O O   . HOH M 5 .   ? 35.897  3.120   21.545  1.00 51.90  ? 738 HOH C O   1 
HETATM 11410 O O   . HOH M 5 .   ? 34.363  -4.752  -12.027 1.00 29.47  ? 739 HOH C O   1 
HETATM 11411 O O   . HOH M 5 .   ? 11.174  8.403   14.145  1.00 28.23  ? 740 HOH C O   1 
HETATM 11412 O O   . HOH M 5 .   ? 3.413   -3.784  15.279  1.00 40.46  ? 741 HOH C O   1 
HETATM 11413 O O   . HOH M 5 .   ? 9.499   -6.775  -11.889 1.00 41.82  ? 742 HOH C O   1 
HETATM 11414 O O   . HOH M 5 .   ? 26.489  6.378   -11.130 1.00 46.61  ? 743 HOH C O   1 
HETATM 11415 O O   . HOH M 5 .   ? 23.731  -20.147 -1.928  1.00 37.87  ? 744 HOH C O   1 
HETATM 11416 O O   . HOH M 5 .   ? 33.095  10.320  11.818  1.00 43.52  ? 745 HOH C O   1 
HETATM 11417 O O   . HOH M 5 .   ? 26.342  -15.046 -15.994 1.00 42.38  ? 746 HOH C O   1 
HETATM 11418 O O   . HOH M 5 .   ? 19.584  20.526  9.356   1.00 42.03  ? 747 HOH C O   1 
HETATM 11419 O O   . HOH M 5 .   ? 41.708  -7.315  -1.299  1.00 40.78  ? 748 HOH C O   1 
HETATM 11420 O O   . HOH M 5 .   ? 27.798  -11.902 18.033  1.00 47.38  ? 749 HOH C O   1 
HETATM 11421 O O   . HOH M 5 .   ? 28.111  -19.990 -8.876  1.00 54.67  ? 750 HOH C O   1 
HETATM 11422 O O   . HOH M 5 .   ? 1.810   -13.227 -5.311  1.00 27.89  ? 751 HOH C O   1 
HETATM 11423 O O   . HOH M 5 .   ? 22.991  -14.890 -23.960 1.00 60.54  ? 752 HOH C O   1 
HETATM 11424 O O   . HOH M 5 .   ? 24.006  -2.524  23.663  1.00 42.65  ? 753 HOH C O   1 
HETATM 11425 O O   . HOH M 5 .   ? 1.733   12.970  11.285  1.00 47.99  ? 754 HOH C O   1 
HETATM 11426 O O   . HOH M 5 .   ? 45.094  -3.898  -26.653 1.00 39.60  ? 755 HOH C O   1 
HETATM 11427 O O   . HOH M 5 .   ? 39.412  -5.370  5.158   1.00 41.57  ? 756 HOH C O   1 
HETATM 11428 O O   . HOH M 5 .   ? 33.951  -17.117 17.152  1.00 53.64  ? 757 HOH C O   1 
HETATM 11429 O O   . HOH M 5 .   ? 23.103  17.833  8.814   1.00 48.54  ? 758 HOH C O   1 
HETATM 11430 O O   . HOH M 5 .   ? 18.775  16.354  22.921  1.00 42.48  ? 759 HOH C O   1 
HETATM 11431 O O   . HOH M 5 .   ? 31.128  -17.398 -12.667 1.00 54.69  ? 760 HOH C O   1 
HETATM 11432 O O   . HOH M 5 .   ? 26.863  -18.121 11.052  1.00 42.99  ? 761 HOH C O   1 
HETATM 11433 O O   . HOH M 5 .   ? 15.475  -8.171  -11.682 1.00 31.88  ? 762 HOH C O   1 
HETATM 11434 O O   . HOH M 5 .   ? 33.163  10.905  16.962  1.00 47.32  ? 763 HOH C O   1 
HETATM 11435 O O   . HOH M 5 .   ? 20.518  -22.593 1.229   1.00 48.54  ? 764 HOH C O   1 
HETATM 11436 O O   . HOH M 5 .   ? 45.023  -7.444  -4.394  1.00 56.69  ? 765 HOH C O   1 
HETATM 11437 O O   . HOH M 5 .   ? 20.346  20.475  6.843   1.00 49.11  ? 766 HOH C O   1 
HETATM 11438 O O   . HOH M 5 .   ? 30.487  -7.036  -9.711  1.00 26.34  ? 767 HOH C O   1 
HETATM 11439 O O   . HOH M 5 .   ? 13.799  24.648  12.513  1.00 34.26  ? 768 HOH C O   1 
HETATM 11440 O O   . HOH M 5 .   ? 9.097   -13.546 7.276   1.00 33.84  ? 769 HOH C O   1 
HETATM 11441 O O   . HOH M 5 .   ? 34.763  17.093  7.792   1.00 46.57  ? 770 HOH C O   1 
HETATM 11442 O O   . HOH M 5 .   ? 9.255   -20.754 8.061   1.00 44.21  ? 771 HOH C O   1 
HETATM 11443 O O   . HOH M 5 .   ? 17.532  18.817  11.422  1.00 44.95  ? 772 HOH C O   1 
HETATM 11444 O O   . HOH M 5 .   ? 25.433  12.740  12.209  1.00 45.91  ? 773 HOH C O   1 
HETATM 11445 O O   . HOH M 5 .   ? 31.216  -8.356  26.501  1.00 48.19  ? 774 HOH C O   1 
HETATM 11446 O O   . HOH M 5 .   ? 22.550  20.019  26.627  1.00 46.37  ? 775 HOH C O   1 
HETATM 11447 O O   . HOH M 5 .   ? 27.654  -21.028 -4.955  1.00 60.11  ? 776 HOH C O   1 
HETATM 11448 O O   . HOH M 5 .   ? 3.713   14.044  14.639  1.00 49.72  ? 777 HOH C O   1 
HETATM 11449 O O   . HOH M 5 .   ? 24.449  10.823  -4.399  1.00 49.82  ? 778 HOH C O   1 
HETATM 11450 O O   . HOH M 5 .   ? 18.775  13.700  26.789  1.00 43.78  ? 779 HOH C O   1 
HETATM 11451 O O   . HOH M 5 .   ? 27.007  -24.003 5.576   1.00 43.31  ? 780 HOH C O   1 
HETATM 11452 O O   . HOH M 5 .   ? 36.309  28.388  -2.065  1.00 57.71  ? 781 HOH C O   1 
HETATM 11453 O O   . HOH M 5 .   ? 29.040  -22.084 2.943   1.00 51.16  ? 782 HOH C O   1 
HETATM 11454 O O   . HOH M 5 .   ? 14.150  -21.249 -2.073  1.00 43.82  ? 783 HOH C O   1 
HETATM 11455 O O   . HOH M 5 .   ? 39.564  -10.598 -29.965 1.00 58.16  ? 784 HOH C O   1 
HETATM 11456 O O   . HOH M 5 .   ? 0.930   10.165  12.449  1.00 34.13  ? 785 HOH C O   1 
HETATM 11457 O O   . HOH M 5 .   ? -0.582  -12.129 -6.040  1.00 30.25  ? 786 HOH C O   1 
HETATM 11458 O O   . HOH M 5 .   ? 22.602  -1.836  -5.637  1.00 40.83  ? 787 HOH C O   1 
HETATM 11459 O O   . HOH M 5 .   ? 22.837  -20.868 0.512   1.00 36.34  ? 788 HOH C O   1 
HETATM 11460 O O   . HOH M 5 .   ? 8.657   -10.212 -10.422 1.00 41.50  ? 789 HOH C O   1 
HETATM 11461 O O   . HOH M 5 .   ? 7.754   -3.030  15.441  1.00 45.72  ? 790 HOH C O   1 
HETATM 11462 O O   . HOH M 5 .   ? 11.506  23.757  16.173  1.00 51.65  ? 791 HOH C O   1 
HETATM 11463 O O   . HOH M 5 .   ? 46.616  -11.901 -20.475 1.00 51.55  ? 792 HOH C O   1 
HETATM 11464 O O   . HOH M 5 .   ? 24.201  -14.765 -17.451 1.00 57.31  ? 793 HOH C O   1 
HETATM 11465 O O   . HOH M 5 .   ? 16.357  0.555   -8.181  1.00 46.93  ? 794 HOH C O   1 
HETATM 11466 O O   . HOH M 5 .   ? 13.895  22.608  14.400  1.00 35.06  ? 795 HOH C O   1 
HETATM 11467 O O   . HOH M 5 .   ? 34.168  -21.044 -8.108  1.00 53.83  ? 796 HOH C O   1 
HETATM 11468 O O   . HOH M 5 .   ? -2.099  3.762   15.741  1.00 49.93  ? 797 HOH C O   1 
HETATM 11469 O O   . HOH M 5 .   ? 24.463  -6.246  -21.366 1.00 50.24  ? 798 HOH C O   1 
HETATM 11470 O O   . HOH M 5 .   ? 19.565  16.053  25.362  1.00 42.84  ? 799 HOH C O   1 
HETATM 11471 O O   . HOH M 5 .   ? 10.193  -2.266  -13.008 1.00 52.35  ? 800 HOH C O   1 
HETATM 11472 O O   . HOH M 5 .   ? 9.250   21.091  19.771  1.00 56.23  ? 801 HOH C O   1 
HETATM 11473 O O   . HOH M 5 .   ? 10.673  -9.458  -12.178 1.00 57.61  ? 802 HOH C O   1 
HETATM 11474 O O   . HOH M 5 .   ? 27.165  -0.408  -18.835 1.00 47.75  ? 803 HOH C O   1 
HETATM 11475 O O   . HOH M 5 .   ? 41.494  -1.040  2.347   1.00 45.07  ? 804 HOH C O   1 
HETATM 11476 O O   . HOH M 5 .   ? 25.868  -9.553  -24.276 1.00 46.72  ? 805 HOH C O   1 
HETATM 11477 O O   . HOH M 5 .   ? 39.769  11.599  -26.109 1.00 61.14  ? 806 HOH C O   1 
HETATM 11478 O O   . HOH M 5 .   ? 27.359  10.464  -8.546  1.00 49.24  ? 807 HOH C O   1 
HETATM 11479 O O   . HOH M 5 .   ? 26.020  10.448  -14.171 1.00 51.11  ? 808 HOH C O   1 
HETATM 11480 O O   . HOH M 5 .   ? 46.089  -9.286  -2.858  1.00 49.95  ? 809 HOH C O   1 
HETATM 11481 O O   . HOH M 5 .   ? 26.189  -20.547 9.931   1.00 49.38  ? 810 HOH C O   1 
HETATM 11482 O O   . HOH M 5 .   ? 43.088  -13.417 -16.090 1.00 46.23  ? 811 HOH C O   1 
HETATM 11483 O O   . HOH M 5 .   ? 25.684  11.141  -11.896 1.00 40.22  ? 812 HOH C O   1 
HETATM 11484 O O   . HOH M 5 .   ? 3.713   -12.805 6.725   1.00 57.10  ? 813 HOH C O   1 
# 
