data_8XXD
# 
_entry.id   8XXD 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XXD         pdb_00008xxd 10.2210/pdb8xxd/pdb 
WWPDB D_1300044051 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XXD 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yl521gl@ustc.edu.cn 
_pdbx_contact_author.name_first         Lin 
_pdbx_contact_author.name_last          Yang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1550-6947 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, L.'   1 0000-0003-1550-6947 
'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'TtCS-citrate-CoA complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, L.'   1 0000-0003-1550-6947 
primary 'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Citrate synthase' 51100.664 3   2.3.3.16 ? ? ? 
2 non-polymer syn 'COENZYME A'       767.534   2   ?        ? ? ? 
3 non-polymer syn 'OXALOACETATE ION' 131.064   2   ?        ? ? ? 
4 non-polymer syn 'CITRIC ACID'      192.124   1   ?        ? ? ? 
5 water       nat water              18.015    183 ?        ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        CS 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGSKLAAALE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGSKLAAALE
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'COENZYME A'       COA 
3 'OXALOACETATE ION' OAA 
4 'CITRIC ACID'      CIT 
5 water              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   LEU n 
1 4   LYS n 
1 5   GLU n 
1 6   ARG n 
1 7   LEU n 
1 8   ALA n 
1 9   GLU n 
1 10  LEU n 
1 11  ILE n 
1 12  PRO n 
1 13  GLN n 
1 14  TRP n 
1 15  ARG n 
1 16  ALA n 
1 17  GLU n 
1 18  VAL n 
1 19  ALA n 
1 20  GLU n 
1 21  ILE n 
1 22  ARG n 
1 23  LYS n 
1 24  LYS n 
1 25  TYR n 
1 26  GLY n 
1 27  ASN n 
1 28  ARG n 
1 29  LYS n 
1 30  THR n 
1 31  MET n 
1 32  ASP n 
1 33  CYS n 
1 34  THR n 
1 35  ILE n 
1 36  GLY n 
1 37  HIS n 
1 38  ALA n 
1 39  TYR n 
1 40  GLY n 
1 41  GLY n 
1 42  MET n 
1 43  ARG n 
1 44  GLY n 
1 45  LEU n 
1 46  LYS n 
1 47  ALA n 
1 48  LEU n 
1 49  VAL n 
1 50  CYS n 
1 51  ASP n 
1 52  THR n 
1 53  SER n 
1 54  GLU n 
1 55  VAL n 
1 56  PHE n 
1 57  PRO n 
1 58  ASP n 
1 59  GLU n 
1 60  GLY n 
1 61  VAL n 
1 62  LYS n 
1 63  PHE n 
1 64  ARG n 
1 65  GLY n 
1 66  TYR n 
1 67  THR n 
1 68  ILE n 
1 69  PRO n 
1 70  GLU n 
1 71  LEU n 
1 72  ARG n 
1 73  GLU n 
1 74  GLY n 
1 75  PRO n 
1 76  HIS n 
1 77  LYS n 
1 78  LEU n 
1 79  PRO n 
1 80  THR n 
1 81  ALA n 
1 82  GLU n 
1 83  GLY n 
1 84  GLY n 
1 85  PHE n 
1 86  GLU n 
1 87  PRO n 
1 88  LEU n 
1 89  PRO n 
1 90  GLU n 
1 91  GLY n 
1 92  LEU n 
1 93  TRP n 
1 94  TYR n 
1 95  LEU n 
1 96  LEU n 
1 97  LEU n 
1 98  THR n 
1 99  GLY n 
1 100 GLU n 
1 101 LEU n 
1 102 PRO n 
1 103 THR n 
1 104 GLU n 
1 105 GLU n 
1 106 ASP n 
1 107 VAL n 
1 108 LYS n 
1 109 GLU n 
1 110 ILE n 
1 111 SER n 
1 112 ALA n 
1 113 GLU n 
1 114 PHE n 
1 115 THR n 
1 116 LYS n 
1 117 ARG n 
1 118 MET n 
1 119 GLN n 
1 120 ASN n 
1 121 VAL n 
1 122 PRO n 
1 123 GLN n 
1 124 TYR n 
1 125 VAL n 
1 126 PHE n 
1 127 ASP n 
1 128 VAL n 
1 129 LEU n 
1 130 ARG n 
1 131 ALA n 
1 132 MET n 
1 133 PRO n 
1 134 VAL n 
1 135 ASP n 
1 136 THR n 
1 137 HIS n 
1 138 PRO n 
1 139 MET n 
1 140 THR n 
1 141 MET n 
1 142 PHE n 
1 143 ALA n 
1 144 ALA n 
1 145 GLY n 
1 146 ILE n 
1 147 LEU n 
1 148 ALA n 
1 149 MET n 
1 150 GLN n 
1 151 ARG n 
1 152 GLU n 
1 153 SER n 
1 154 VAL n 
1 155 PHE n 
1 156 ALA n 
1 157 LYS n 
1 158 ARG n 
1 159 TYR n 
1 160 GLU n 
1 161 GLU n 
1 162 GLY n 
1 163 MET n 
1 164 ARG n 
1 165 ARG n 
1 166 GLU n 
1 167 GLU n 
1 168 HIS n 
1 169 TRP n 
1 170 GLU n 
1 171 ALA n 
1 172 MET n 
1 173 LEU n 
1 174 GLU n 
1 175 ASP n 
1 176 SER n 
1 177 LEU n 
1 178 ASN n 
1 179 MET n 
1 180 LEU n 
1 181 ALA n 
1 182 ALA n 
1 183 LEU n 
1 184 PRO n 
1 185 VAL n 
1 186 ILE n 
1 187 ALA n 
1 188 ALA n 
1 189 TYR n 
1 190 ILE n 
1 191 TYR n 
1 192 ARG n 
1 193 ARG n 
1 194 LYS n 
1 195 TYR n 
1 196 LYS n 
1 197 GLY n 
1 198 ASP n 
1 199 THR n 
1 200 HIS n 
1 201 ILE n 
1 202 ALA n 
1 203 PRO n 
1 204 ASP n 
1 205 PRO n 
1 206 ASN n 
1 207 LEU n 
1 208 ASP n 
1 209 TRP n 
1 210 SER n 
1 211 ALA n 
1 212 ASN n 
1 213 LEU n 
1 214 ALA n 
1 215 HIS n 
1 216 MET n 
1 217 MET n 
1 218 GLY n 
1 219 PHE n 
1 220 ASP n 
1 221 ASP n 
1 222 PHE n 
1 223 GLU n 
1 224 VAL n 
1 225 TYR n 
1 226 GLU n 
1 227 LEU n 
1 228 PHE n 
1 229 ARG n 
1 230 LEU n 
1 231 TYR n 
1 232 MET n 
1 233 PHE n 
1 234 LEU n 
1 235 HIS n 
1 236 SER n 
1 237 ASP n 
1 238 HIS n 
1 239 GLU n 
1 240 GLY n 
1 241 GLY n 
1 242 ASN n 
1 243 VAL n 
1 244 SER n 
1 245 ALA n 
1 246 HIS n 
1 247 THR n 
1 248 ASN n 
1 249 LEU n 
1 250 LEU n 
1 251 VAL n 
1 252 ASN n 
1 253 SER n 
1 254 ALA n 
1 255 TYR n 
1 256 SER n 
1 257 ASP n 
1 258 ILE n 
1 259 TYR n 
1 260 ARG n 
1 261 SER n 
1 262 PHE n 
1 263 SER n 
1 264 ALA n 
1 265 ALA n 
1 266 MET n 
1 267 ASN n 
1 268 GLY n 
1 269 LEU n 
1 270 ALA n 
1 271 GLY n 
1 272 PRO n 
1 273 LEU n 
1 274 HIS n 
1 275 GLY n 
1 276 LEU n 
1 277 ALA n 
1 278 ASN n 
1 279 GLN n 
1 280 GLU n 
1 281 VAL n 
1 282 LEU n 
1 283 ARG n 
1 284 TRP n 
1 285 ILE n 
1 286 GLN n 
1 287 MET n 
1 288 LEU n 
1 289 TYR n 
1 290 LYS n 
1 291 LYS n 
1 292 PHE n 
1 293 GLY n 
1 294 GLY n 
1 295 VAL n 
1 296 PRO n 
1 297 THR n 
1 298 LYS n 
1 299 GLU n 
1 300 GLN n 
1 301 LEU n 
1 302 GLU n 
1 303 ARG n 
1 304 PHE n 
1 305 ALA n 
1 306 TRP n 
1 307 ASP n 
1 308 THR n 
1 309 LEU n 
1 310 ASN n 
1 311 SER n 
1 312 GLY n 
1 313 GLN n 
1 314 VAL n 
1 315 ILE n 
1 316 PRO n 
1 317 GLY n 
1 318 TYR n 
1 319 GLY n 
1 320 HIS n 
1 321 ALA n 
1 322 VAL n 
1 323 LEU n 
1 324 ARG n 
1 325 VAL n 
1 326 THR n 
1 327 ASP n 
1 328 PRO n 
1 329 ARG n 
1 330 TYR n 
1 331 VAL n 
1 332 ALA n 
1 333 GLN n 
1 334 ARG n 
1 335 ASP n 
1 336 PHE n 
1 337 ALA n 
1 338 LEU n 
1 339 LYS n 
1 340 HIS n 
1 341 LEU n 
1 342 PRO n 
1 343 ASP n 
1 344 ASP n 
1 345 GLU n 
1 346 LEU n 
1 347 PHE n 
1 348 LYS n 
1 349 ILE n 
1 350 VAL n 
1 351 SER n 
1 352 LEU n 
1 353 CYS n 
1 354 TYR n 
1 355 GLU n 
1 356 VAL n 
1 357 ILE n 
1 358 PRO n 
1 359 GLU n 
1 360 VAL n 
1 361 LEU n 
1 362 LYS n 
1 363 LYS n 
1 364 HIS n 
1 365 GLY n 
1 366 LYS n 
1 367 ALA n 
1 368 LYS n 
1 369 ASN n 
1 370 PRO n 
1 371 TRP n 
1 372 PRO n 
1 373 ASN n 
1 374 VAL n 
1 375 ASP n 
1 376 ALA n 
1 377 HIS n 
1 378 SER n 
1 379 GLY n 
1 380 VAL n 
1 381 LEU n 
1 382 LEU n 
1 383 TRP n 
1 384 HIS n 
1 385 TYR n 
1 386 GLY n 
1 387 ILE n 
1 388 ARG n 
1 389 GLU n 
1 390 TYR n 
1 391 ASP n 
1 392 PHE n 
1 393 TYR n 
1 394 THR n 
1 395 VAL n 
1 396 LEU n 
1 397 PHE n 
1 398 GLY n 
1 399 VAL n 
1 400 SER n 
1 401 ARG n 
1 402 ALA n 
1 403 LEU n 
1 404 GLY n 
1 405 CYS n 
1 406 THR n 
1 407 ALA n 
1 408 GLN n 
1 409 ALA n 
1 410 ILE n 
1 411 LEU n 
1 412 VAL n 
1 413 ARG n 
1 414 GLY n 
1 415 TYR n 
1 416 MET n 
1 417 LEU n 
1 418 PRO n 
1 419 ILE n 
1 420 GLU n 
1 421 ARG n 
1 422 PRO n 
1 423 LYS n 
1 424 SER n 
1 425 ILE n 
1 426 THR n 
1 427 THR n 
1 428 ARG n 
1 429 TRP n 
1 430 VAL n 
1 431 LYS n 
1 432 GLU n 
1 433 VAL n 
1 434 ALA n 
1 435 GLU n 
1 436 SER n 
1 437 LEU n 
1 438 PRO n 
1 439 VAL n 
1 440 ALA n 
1 441 GLY n 
1 442 SER n 
1 443 LYS n 
1 444 LEU n 
1 445 ALA n 
1 446 ALA n 
1 447 ALA n 
1 448 LEU n 
1 449 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   449 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 gltA 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ABI70S6 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Thermosulfidibacter takaii ABI70S6' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1298851 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE            ? 'C3 H7 N O2'          89.093  
ARG 'L-peptide linking' y ARGININE           ? 'C6 H15 N4 O2 1'      175.209 
ASN 'L-peptide linking' y ASPARAGINE         ? 'C4 H8 N2 O3'         132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'    ? 'C4 H7 N O4'          133.103 
CIT non-polymer         . 'CITRIC ACID'      ? 'C6 H8 O7'            192.124 
COA non-polymer         . 'COENZYME A'       ? 'C21 H36 N7 O16 P3 S' 767.534 
CYS 'L-peptide linking' y CYSTEINE           ? 'C3 H7 N O2 S'        121.158 
GLN 'L-peptide linking' y GLUTAMINE          ? 'C5 H10 N2 O3'        146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'    ? 'C5 H9 N O4'          147.129 
GLY 'peptide linking'   y GLYCINE            ? 'C2 H5 N O2'          75.067  
HIS 'L-peptide linking' y HISTIDINE          ? 'C6 H10 N3 O2 1'      156.162 
HOH non-polymer         . WATER              ? 'H2 O'                18.015  
ILE 'L-peptide linking' y ISOLEUCINE         ? 'C6 H13 N O2'         131.173 
LEU 'L-peptide linking' y LEUCINE            ? 'C6 H13 N O2'         131.173 
LYS 'L-peptide linking' y LYSINE             ? 'C6 H15 N2 O2 1'      147.195 
MET 'L-peptide linking' y METHIONINE         ? 'C5 H11 N O2 S'       149.211 
OAA non-polymer         . 'OXALOACETATE ION' ? 'C4 H3 O5 -1'         131.064 
PHE 'L-peptide linking' y PHENYLALANINE      ? 'C9 H11 N O2'         165.189 
PRO 'L-peptide linking' y PROLINE            ? 'C5 H9 N O2'          115.130 
SER 'L-peptide linking' y SERINE             ? 'C3 H7 N O3'          105.093 
THR 'L-peptide linking' y THREONINE          ? 'C4 H9 N O3'          119.119 
TRP 'L-peptide linking' y TRYPTOPHAN         ? 'C11 H12 N2 O2'       204.225 
TYR 'L-peptide linking' y TYROSINE           ? 'C9 H11 N O3'         181.189 
VAL 'L-peptide linking' y VALINE             ? 'C5 H11 N O2'         117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   LYS 4   4   4   LYS LYS A . n 
A 1 5   GLU 5   5   5   GLU GLU A . n 
A 1 6   ARG 6   6   6   ARG ARG A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   ALA 8   8   8   ALA ALA A . n 
A 1 9   GLU 9   9   9   GLU GLU A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  ILE 11  11  11  ILE ILE A . n 
A 1 12  PRO 12  12  12  PRO PRO A . n 
A 1 13  GLN 13  13  13  GLN GLN A . n 
A 1 14  TRP 14  14  14  TRP TRP A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  ALA 19  19  19  ALA ALA A . n 
A 1 20  GLU 20  20  20  GLU GLU A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  ARG 22  22  22  ARG ARG A . n 
A 1 23  LYS 23  23  23  LYS LYS A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  TYR 25  25  25  TYR TYR A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  ASN 27  27  27  ASN ASN A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  CYS 33  33  33  CYS CYS A . n 
A 1 34  THR 34  34  34  THR THR A . n 
A 1 35  ILE 35  35  35  ILE ILE A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  HIS 37  37  37  HIS HIS A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  TYR 39  39  39  TYR TYR A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  MET 42  42  42  MET MET A . n 
A 1 43  ARG 43  43  43  ARG ARG A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ALA 47  47  47  ALA ALA A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  VAL 49  49  49  VAL VAL A . n 
A 1 50  CYS 50  50  50  CYS CYS A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  THR 52  52  52  THR THR A . n 
A 1 53  SER 53  53  53  SER SER A . n 
A 1 54  GLU 54  54  54  GLU GLU A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  GLY 60  60  60  GLY GLY A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  PHE 63  63  63  PHE PHE A . n 
A 1 64  ARG 64  64  64  ARG ARG A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  TYR 66  66  66  TYR TYR A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  PRO 69  69  69  PRO PRO A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  ARG 72  72  72  ARG ARG A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  GLY 74  74  74  GLY GLY A . n 
A 1 75  PRO 75  75  75  PRO PRO A . n 
A 1 76  HIS 76  76  76  HIS HIS A . n 
A 1 77  LYS 77  77  77  LYS LYS A . n 
A 1 78  LEU 78  78  78  LEU LEU A . n 
A 1 79  PRO 79  79  79  PRO PRO A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  ALA 81  81  81  ALA ALA A . n 
A 1 82  GLU 82  82  82  GLU GLU A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  GLY 84  84  84  GLY GLY A . n 
A 1 85  PHE 85  85  85  PHE PHE A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  PRO 87  87  87  PRO PRO A . n 
A 1 88  LEU 88  88  88  LEU LEU A . n 
A 1 89  PRO 89  89  89  PRO PRO A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  LEU 92  92  92  LEU LEU A . n 
A 1 93  TRP 93  93  93  TRP TRP A . n 
A 1 94  TYR 94  94  94  TYR TYR A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  LEU 96  96  96  LEU LEU A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 GLU 100 100 100 GLU GLU A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 PRO 102 102 102 PRO PRO A . n 
A 1 103 THR 103 103 103 THR THR A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 GLU 105 105 105 GLU GLU A . n 
A 1 106 ASP 106 106 106 ASP ASP A . n 
A 1 107 VAL 107 107 107 VAL VAL A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 GLU 109 109 109 GLU GLU A . n 
A 1 110 ILE 110 110 110 ILE ILE A . n 
A 1 111 SER 111 111 111 SER SER A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 GLU 113 113 113 GLU GLU A . n 
A 1 114 PHE 114 114 114 PHE PHE A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 ARG 117 117 117 ARG ARG A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 GLN 119 119 119 GLN GLN A . n 
A 1 120 ASN 120 120 120 ASN ASN A . n 
A 1 121 VAL 121 121 121 VAL VAL A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 GLN 123 123 123 GLN GLN A . n 
A 1 124 TYR 124 124 124 TYR TYR A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 PHE 126 126 126 PHE PHE A . n 
A 1 127 ASP 127 127 127 ASP ASP A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 ARG 130 130 130 ARG ARG A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 VAL 134 134 134 VAL VAL A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 HIS 137 137 137 HIS HIS A . n 
A 1 138 PRO 138 138 138 PRO PRO A . n 
A 1 139 MET 139 139 139 MET MET A . n 
A 1 140 THR 140 140 140 THR THR A . n 
A 1 141 MET 141 141 141 MET MET A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 MET 149 149 149 MET MET A . n 
A 1 150 GLN 150 150 150 GLN GLN A . n 
A 1 151 ARG 151 151 151 ARG ARG A . n 
A 1 152 GLU 152 152 152 GLU GLU A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 VAL 154 154 154 VAL VAL A . n 
A 1 155 PHE 155 155 155 PHE PHE A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 LYS 157 157 157 LYS LYS A . n 
A 1 158 ARG 158 158 158 ARG ARG A . n 
A 1 159 TYR 159 159 159 TYR TYR A . n 
A 1 160 GLU 160 160 160 GLU GLU A . n 
A 1 161 GLU 161 161 161 GLU GLU A . n 
A 1 162 GLY 162 162 162 GLY GLY A . n 
A 1 163 MET 163 163 163 MET MET A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 ARG 165 165 165 ARG ARG A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 GLU 167 167 167 GLU GLU A . n 
A 1 168 HIS 168 168 168 HIS HIS A . n 
A 1 169 TRP 169 169 169 TRP TRP A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 ALA 171 171 171 ALA ALA A . n 
A 1 172 MET 172 172 172 MET MET A . n 
A 1 173 LEU 173 173 173 LEU LEU A . n 
A 1 174 GLU 174 174 174 GLU GLU A . n 
A 1 175 ASP 175 175 175 ASP ASP A . n 
A 1 176 SER 176 176 176 SER SER A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 ASN 178 178 178 ASN ASN A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 ALA 181 181 181 ALA ALA A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 LEU 183 183 183 LEU LEU A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 ILE 186 186 186 ILE ILE A . n 
A 1 187 ALA 187 187 187 ALA ALA A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 TYR 189 189 189 TYR TYR A . n 
A 1 190 ILE 190 190 190 ILE ILE A . n 
A 1 191 TYR 191 191 191 TYR TYR A . n 
A 1 192 ARG 192 192 192 ARG ARG A . n 
A 1 193 ARG 193 193 193 ARG ARG A . n 
A 1 194 LYS 194 194 194 LYS LYS A . n 
A 1 195 TYR 195 195 195 TYR TYR A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 GLY 197 197 197 GLY GLY A . n 
A 1 198 ASP 198 198 198 ASP ASP A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 HIS 200 200 200 HIS HIS A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 PRO 203 203 203 PRO PRO A . n 
A 1 204 ASP 204 204 204 ASP ASP A . n 
A 1 205 PRO 205 205 205 PRO PRO A . n 
A 1 206 ASN 206 206 206 ASN ASN A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 ASP 208 208 208 ASP ASP A . n 
A 1 209 TRP 209 209 209 TRP TRP A . n 
A 1 210 SER 210 210 210 SER SER A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 ASN 212 212 212 ASN ASN A . n 
A 1 213 LEU 213 213 213 LEU LEU A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 HIS 215 215 215 HIS HIS A . n 
A 1 216 MET 216 216 216 MET MET A . n 
A 1 217 MET 217 217 217 MET MET A . n 
A 1 218 GLY 218 218 218 GLY GLY A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 ASP 220 220 220 ASP ASP A . n 
A 1 221 ASP 221 221 221 ASP ASP A . n 
A 1 222 PHE 222 222 222 PHE PHE A . n 
A 1 223 GLU 223 223 223 GLU GLU A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 TYR 225 225 225 TYR TYR A . n 
A 1 226 GLU 226 226 226 GLU GLU A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 PHE 228 228 228 PHE PHE A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 TYR 231 231 231 TYR TYR A . n 
A 1 232 MET 232 232 232 MET MET A . n 
A 1 233 PHE 233 233 233 PHE PHE A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 HIS 235 235 235 HIS HIS A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 HIS 238 238 238 HIS HIS A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 GLY 240 240 240 GLY GLY A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 ASN 242 242 242 ASN ASN A . n 
A 1 243 VAL 243 243 243 VAL VAL A . n 
A 1 244 SER 244 244 244 SER SER A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 THR 247 247 247 THR THR A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 ASN 252 252 252 ASN ASN A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 ALA 254 254 254 ALA ALA A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 ASP 257 257 257 ASP ASP A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 TYR 259 259 259 TYR TYR A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 SER 261 261 261 SER SER A . n 
A 1 262 PHE 262 262 262 PHE PHE A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ALA 264 264 264 ALA ALA A . n 
A 1 265 ALA 265 265 265 ALA ALA A . n 
A 1 266 MET 266 266 266 MET MET A . n 
A 1 267 ASN 267 267 267 ASN ASN A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 PRO 272 272 272 PRO PRO A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 HIS 274 274 274 HIS HIS A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 ASN 278 278 278 ASN ASN A . n 
A 1 279 GLN 279 279 279 GLN GLN A . n 
A 1 280 GLU 280 280 280 GLU GLU A . n 
A 1 281 VAL 281 281 281 VAL VAL A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 ARG 283 283 283 ARG ARG A . n 
A 1 284 TRP 284 284 284 TRP TRP A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 GLN 286 286 286 GLN GLN A . n 
A 1 287 MET 287 287 287 MET MET A . n 
A 1 288 LEU 288 288 288 LEU LEU A . n 
A 1 289 TYR 289 289 289 TYR TYR A . n 
A 1 290 LYS 290 290 290 LYS LYS A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 PHE 292 292 292 PHE PHE A . n 
A 1 293 GLY 293 293 293 GLY GLY A . n 
A 1 294 GLY 294 294 294 GLY GLY A . n 
A 1 295 VAL 295 295 295 VAL VAL A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 LYS 298 298 298 LYS LYS A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 GLN 300 300 300 GLN GLN A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 GLU 302 302 302 GLU GLU A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 PHE 304 304 304 PHE PHE A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 TRP 306 306 306 TRP TRP A . n 
A 1 307 ASP 307 307 307 ASP ASP A . n 
A 1 308 THR 308 308 308 THR THR A . n 
A 1 309 LEU 309 309 309 LEU LEU A . n 
A 1 310 ASN 310 310 310 ASN ASN A . n 
A 1 311 SER 311 311 311 SER SER A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 GLY 317 317 317 GLY GLY A . n 
A 1 318 TYR 318 318 318 TYR TYR A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 HIS 320 320 320 HIS HIS A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 VAL 322 322 322 VAL VAL A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 ARG 324 324 324 ARG ARG A . n 
A 1 325 VAL 325 325 325 VAL VAL A . n 
A 1 326 THR 326 326 326 THR THR A . n 
A 1 327 ASP 327 327 327 ASP ASP A . n 
A 1 328 PRO 328 328 328 PRO PRO A . n 
A 1 329 ARG 329 329 329 ARG ARG A . n 
A 1 330 TYR 330 330 330 TYR TYR A . n 
A 1 331 VAL 331 331 331 VAL VAL A . n 
A 1 332 ALA 332 332 332 ALA ALA A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 LYS 339 339 339 LYS LYS A . n 
A 1 340 HIS 340 340 340 HIS HIS A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 PRO 342 342 342 PRO PRO A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 ASP 344 344 344 ASP ASP A . n 
A 1 345 GLU 345 345 345 GLU GLU A . n 
A 1 346 LEU 346 346 346 LEU LEU A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 LYS 348 348 348 LYS LYS A . n 
A 1 349 ILE 349 349 349 ILE ILE A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 CYS 353 353 353 CYS CYS A . n 
A 1 354 TYR 354 354 354 TYR TYR A . n 
A 1 355 GLU 355 355 355 GLU GLU A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 GLU 359 359 359 GLU GLU A . n 
A 1 360 VAL 360 360 360 VAL VAL A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 LYS 362 362 362 LYS LYS A . n 
A 1 363 LYS 363 363 363 LYS LYS A . n 
A 1 364 HIS 364 364 364 HIS HIS A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 LYS 366 366 366 LYS LYS A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 LYS 368 368 368 LYS LYS A . n 
A 1 369 ASN 369 369 369 ASN ASN A . n 
A 1 370 PRO 370 370 370 PRO PRO A . n 
A 1 371 TRP 371 371 371 TRP TRP A . n 
A 1 372 PRO 372 372 372 PRO PRO A . n 
A 1 373 ASN 373 373 373 ASN ASN A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 ASP 375 375 375 ASP ASP A . n 
A 1 376 ALA 376 376 376 ALA ALA A . n 
A 1 377 HIS 377 377 377 HIS HIS A . n 
A 1 378 SER 378 378 378 SER SER A . n 
A 1 379 GLY 379 379 379 GLY GLY A . n 
A 1 380 VAL 380 380 380 VAL VAL A . n 
A 1 381 LEU 381 381 381 LEU LEU A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 TRP 383 383 383 TRP TRP A . n 
A 1 384 HIS 384 384 384 HIS HIS A . n 
A 1 385 TYR 385 385 385 TYR TYR A . n 
A 1 386 GLY 386 386 386 GLY GLY A . n 
A 1 387 ILE 387 387 387 ILE ILE A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 GLU 389 389 389 GLU GLU A . n 
A 1 390 TYR 390 390 390 TYR TYR A . n 
A 1 391 ASP 391 391 391 ASP ASP A . n 
A 1 392 PHE 392 392 392 PHE PHE A . n 
A 1 393 TYR 393 393 393 TYR TYR A . n 
A 1 394 THR 394 394 394 THR THR A . n 
A 1 395 VAL 395 395 395 VAL VAL A . n 
A 1 396 LEU 396 396 396 LEU LEU A . n 
A 1 397 PHE 397 397 397 PHE PHE A . n 
A 1 398 GLY 398 398 398 GLY GLY A . n 
A 1 399 VAL 399 399 399 VAL VAL A . n 
A 1 400 SER 400 400 400 SER SER A . n 
A 1 401 ARG 401 401 401 ARG ARG A . n 
A 1 402 ALA 402 402 402 ALA ALA A . n 
A 1 403 LEU 403 403 403 LEU LEU A . n 
A 1 404 GLY 404 404 404 GLY GLY A . n 
A 1 405 CYS 405 405 405 CYS CYS A . n 
A 1 406 THR 406 406 406 THR THR A . n 
A 1 407 ALA 407 407 407 ALA ALA A . n 
A 1 408 GLN 408 408 408 GLN GLN A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 ILE 410 410 410 ILE ILE A . n 
A 1 411 LEU 411 411 411 LEU LEU A . n 
A 1 412 VAL 412 412 412 VAL VAL A . n 
A 1 413 ARG 413 413 413 ARG ARG A . n 
A 1 414 GLY 414 414 414 GLY GLY A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 MET 416 416 416 MET MET A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 PRO 418 418 418 PRO PRO A . n 
A 1 419 ILE 419 419 419 ILE ILE A . n 
A 1 420 GLU 420 420 420 GLU GLU A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 PRO 422 422 422 PRO PRO A . n 
A 1 423 LYS 423 423 423 LYS LYS A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 ILE 425 425 425 ILE ILE A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 THR 427 427 427 THR THR A . n 
A 1 428 ARG 428 428 428 ARG ARG A . n 
A 1 429 TRP 429 429 429 TRP TRP A . n 
A 1 430 VAL 430 430 430 VAL VAL A . n 
A 1 431 LYS 431 431 431 LYS LYS A . n 
A 1 432 GLU 432 432 432 GLU GLU A . n 
A 1 433 VAL 433 433 433 VAL VAL A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 GLU 435 435 435 GLU GLU A . n 
A 1 436 SER 436 436 436 SER SER A . n 
A 1 437 LEU 437 437 437 LEU LEU A . n 
A 1 438 PRO 438 438 438 PRO PRO A . n 
A 1 439 VAL 439 439 439 VAL VAL A . n 
A 1 440 ALA 440 440 440 ALA ALA A . n 
A 1 441 GLY 441 441 441 GLY GLY A . n 
A 1 442 SER 442 442 442 SER SER A . n 
A 1 443 LYS 443 443 443 LYS LYS A . n 
A 1 444 LEU 444 444 444 LEU LEU A . n 
A 1 445 ALA 445 445 445 ALA ALA A . n 
A 1 446 ALA 446 446 446 ALA ALA A . n 
A 1 447 ALA 447 447 447 ALA ALA A . n 
A 1 448 LEU 448 448 448 LEU LEU A . n 
A 1 449 GLU 449 449 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   LYS 2   2   2   LYS LYS B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   LYS 4   4   4   LYS LYS B . n 
B 1 5   GLU 5   5   5   GLU GLU B . n 
B 1 6   ARG 6   6   6   ARG ARG B . n 
B 1 7   LEU 7   7   7   LEU LEU B . n 
B 1 8   ALA 8   8   8   ALA ALA B . n 
B 1 9   GLU 9   9   9   GLU GLU B . n 
B 1 10  LEU 10  10  10  LEU LEU B . n 
B 1 11  ILE 11  11  11  ILE ILE B . n 
B 1 12  PRO 12  12  12  PRO PRO B . n 
B 1 13  GLN 13  13  13  GLN GLN B . n 
B 1 14  TRP 14  14  14  TRP TRP B . n 
B 1 15  ARG 15  15  15  ARG ARG B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  GLU 17  17  17  GLU GLU B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  ALA 19  19  19  ALA ALA B . n 
B 1 20  GLU 20  20  20  GLU GLU B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  ARG 22  22  22  ARG ARG B . n 
B 1 23  LYS 23  23  23  LYS LYS B . n 
B 1 24  LYS 24  24  24  LYS LYS B . n 
B 1 25  TYR 25  25  25  TYR TYR B . n 
B 1 26  GLY 26  26  26  GLY GLY B . n 
B 1 27  ASN 27  27  27  ASN ASN B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  LYS 29  29  29  LYS LYS B . n 
B 1 30  THR 30  30  30  THR THR B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  ASP 32  32  32  ASP ASP B . n 
B 1 33  CYS 33  33  33  CYS CYS B . n 
B 1 34  THR 34  34  34  THR THR B . n 
B 1 35  ILE 35  35  35  ILE ILE B . n 
B 1 36  GLY 36  36  36  GLY GLY B . n 
B 1 37  HIS 37  37  37  HIS HIS B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  TYR 39  39  39  TYR TYR B . n 
B 1 40  GLY 40  40  40  GLY GLY B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  MET 42  42  42  MET MET B . n 
B 1 43  ARG 43  43  43  ARG ARG B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  LEU 45  45  45  LEU LEU B . n 
B 1 46  LYS 46  46  46  LYS LYS B . n 
B 1 47  ALA 47  47  47  ALA ALA B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  VAL 49  49  49  VAL VAL B . n 
B 1 50  CYS 50  50  50  CYS CYS B . n 
B 1 51  ASP 51  51  51  ASP ASP B . n 
B 1 52  THR 52  52  52  THR THR B . n 
B 1 53  SER 53  53  53  SER SER B . n 
B 1 54  GLU 54  54  54  GLU GLU B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  PHE 56  56  56  PHE PHE B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  GLY 60  60  60  GLY GLY B . n 
B 1 61  VAL 61  61  61  VAL VAL B . n 
B 1 62  LYS 62  62  62  LYS LYS B . n 
B 1 63  PHE 63  63  63  PHE PHE B . n 
B 1 64  ARG 64  64  64  ARG ARG B . n 
B 1 65  GLY 65  65  65  GLY GLY B . n 
B 1 66  TYR 66  66  66  TYR TYR B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  ILE 68  68  68  ILE ILE B . n 
B 1 69  PRO 69  69  69  PRO PRO B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  ARG 72  72  72  ARG ARG B . n 
B 1 73  GLU 73  73  73  GLU GLU B . n 
B 1 74  GLY 74  74  74  GLY GLY B . n 
B 1 75  PRO 75  75  75  PRO PRO B . n 
B 1 76  HIS 76  76  76  HIS HIS B . n 
B 1 77  LYS 77  77  77  LYS LYS B . n 
B 1 78  LEU 78  78  78  LEU LEU B . n 
B 1 79  PRO 79  79  79  PRO PRO B . n 
B 1 80  THR 80  80  80  THR THR B . n 
B 1 81  ALA 81  81  81  ALA ALA B . n 
B 1 82  GLU 82  82  82  GLU GLU B . n 
B 1 83  GLY 83  83  83  GLY GLY B . n 
B 1 84  GLY 84  84  84  GLY GLY B . n 
B 1 85  PHE 85  85  85  PHE PHE B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  PRO 87  87  87  PRO PRO B . n 
B 1 88  LEU 88  88  88  LEU LEU B . n 
B 1 89  PRO 89  89  89  PRO PRO B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLY 91  91  91  GLY GLY B . n 
B 1 92  LEU 92  92  92  LEU LEU B . n 
B 1 93  TRP 93  93  93  TRP TRP B . n 
B 1 94  TYR 94  94  94  TYR TYR B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  LEU 96  96  96  LEU LEU B . n 
B 1 97  LEU 97  97  97  LEU LEU B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  GLY 99  99  99  GLY GLY B . n 
B 1 100 GLU 100 100 100 GLU GLU B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 PRO 102 102 102 PRO PRO B . n 
B 1 103 THR 103 103 103 THR THR B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 GLU 105 105 105 GLU GLU B . n 
B 1 106 ASP 106 106 106 ASP ASP B . n 
B 1 107 VAL 107 107 107 VAL VAL B . n 
B 1 108 LYS 108 108 108 LYS LYS B . n 
B 1 109 GLU 109 109 109 GLU GLU B . n 
B 1 110 ILE 110 110 110 ILE ILE B . n 
B 1 111 SER 111 111 111 SER SER B . n 
B 1 112 ALA 112 112 112 ALA ALA B . n 
B 1 113 GLU 113 113 113 GLU GLU B . n 
B 1 114 PHE 114 114 114 PHE PHE B . n 
B 1 115 THR 115 115 115 THR THR B . n 
B 1 116 LYS 116 116 116 LYS LYS B . n 
B 1 117 ARG 117 117 117 ARG ARG B . n 
B 1 118 MET 118 118 118 MET MET B . n 
B 1 119 GLN 119 119 119 GLN GLN B . n 
B 1 120 ASN 120 120 120 ASN ASN B . n 
B 1 121 VAL 121 121 121 VAL VAL B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 GLN 123 123 123 GLN GLN B . n 
B 1 124 TYR 124 124 124 TYR TYR B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 PHE 126 126 126 PHE PHE B . n 
B 1 127 ASP 127 127 127 ASP ASP B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 ARG 130 130 130 ARG ARG B . n 
B 1 131 ALA 131 131 131 ALA ALA B . n 
B 1 132 MET 132 132 132 MET MET B . n 
B 1 133 PRO 133 133 133 PRO PRO B . n 
B 1 134 VAL 134 134 134 VAL VAL B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 THR 136 136 136 THR THR B . n 
B 1 137 HIS 137 137 137 HIS HIS B . n 
B 1 138 PRO 138 138 138 PRO PRO B . n 
B 1 139 MET 139 139 139 MET MET B . n 
B 1 140 THR 140 140 140 THR THR B . n 
B 1 141 MET 141 141 141 MET MET B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ALA 143 143 143 ALA ALA B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 LEU 147 147 147 LEU LEU B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 MET 149 149 149 MET MET B . n 
B 1 150 GLN 150 150 150 GLN GLN B . n 
B 1 151 ARG 151 151 151 ARG ARG B . n 
B 1 152 GLU 152 152 152 GLU GLU B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 VAL 154 154 154 VAL VAL B . n 
B 1 155 PHE 155 155 155 PHE PHE B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 LYS 157 157 157 LYS LYS B . n 
B 1 158 ARG 158 158 158 ARG ARG B . n 
B 1 159 TYR 159 159 159 TYR TYR B . n 
B 1 160 GLU 160 160 160 GLU GLU B . n 
B 1 161 GLU 161 161 161 GLU GLU B . n 
B 1 162 GLY 162 162 162 GLY GLY B . n 
B 1 163 MET 163 163 163 MET MET B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 ARG 165 165 165 ARG ARG B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 GLU 167 167 167 GLU GLU B . n 
B 1 168 HIS 168 168 168 HIS HIS B . n 
B 1 169 TRP 169 169 169 TRP TRP B . n 
B 1 170 GLU 170 170 170 GLU GLU B . n 
B 1 171 ALA 171 171 171 ALA ALA B . n 
B 1 172 MET 172 172 172 MET MET B . n 
B 1 173 LEU 173 173 173 LEU LEU B . n 
B 1 174 GLU 174 174 174 GLU GLU B . n 
B 1 175 ASP 175 175 175 ASP ASP B . n 
B 1 176 SER 176 176 176 SER SER B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 ASN 178 178 178 ASN ASN B . n 
B 1 179 MET 179 179 179 MET MET B . n 
B 1 180 LEU 180 180 180 LEU LEU B . n 
B 1 181 ALA 181 181 181 ALA ALA B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 LEU 183 183 183 LEU LEU B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 VAL 185 185 185 VAL VAL B . n 
B 1 186 ILE 186 186 186 ILE ILE B . n 
B 1 187 ALA 187 187 187 ALA ALA B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 TYR 189 189 189 TYR TYR B . n 
B 1 190 ILE 190 190 190 ILE ILE B . n 
B 1 191 TYR 191 191 191 TYR TYR B . n 
B 1 192 ARG 192 192 192 ARG ARG B . n 
B 1 193 ARG 193 193 193 ARG ARG B . n 
B 1 194 LYS 194 194 194 LYS LYS B . n 
B 1 195 TYR 195 195 195 TYR TYR B . n 
B 1 196 LYS 196 196 196 LYS LYS B . n 
B 1 197 GLY 197 197 197 GLY GLY B . n 
B 1 198 ASP 198 198 198 ASP ASP B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 HIS 200 200 200 HIS HIS B . n 
B 1 201 ILE 201 201 201 ILE ILE B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 PRO 203 203 203 PRO PRO B . n 
B 1 204 ASP 204 204 204 ASP ASP B . n 
B 1 205 PRO 205 205 205 PRO PRO B . n 
B 1 206 ASN 206 206 206 ASN ASN B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 ASP 208 208 208 ASP ASP B . n 
B 1 209 TRP 209 209 209 TRP TRP B . n 
B 1 210 SER 210 210 210 SER SER B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 ASN 212 212 212 ASN ASN B . n 
B 1 213 LEU 213 213 213 LEU LEU B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 HIS 215 215 215 HIS HIS B . n 
B 1 216 MET 216 216 216 MET MET B . n 
B 1 217 MET 217 217 217 MET MET B . n 
B 1 218 GLY 218 218 218 GLY GLY B . n 
B 1 219 PHE 219 219 219 PHE PHE B . n 
B 1 220 ASP 220 220 220 ASP ASP B . n 
B 1 221 ASP 221 221 221 ASP ASP B . n 
B 1 222 PHE 222 222 222 PHE PHE B . n 
B 1 223 GLU 223 223 223 GLU GLU B . n 
B 1 224 VAL 224 224 224 VAL VAL B . n 
B 1 225 TYR 225 225 225 TYR TYR B . n 
B 1 226 GLU 226 226 226 GLU GLU B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 PHE 228 228 228 PHE PHE B . n 
B 1 229 ARG 229 229 229 ARG ARG B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 TYR 231 231 231 TYR TYR B . n 
B 1 232 MET 232 232 232 MET MET B . n 
B 1 233 PHE 233 233 233 PHE PHE B . n 
B 1 234 LEU 234 234 234 LEU LEU B . n 
B 1 235 HIS 235 235 235 HIS HIS B . n 
B 1 236 SER 236 236 236 SER SER B . n 
B 1 237 ASP 237 237 237 ASP ASP B . n 
B 1 238 HIS 238 238 238 HIS HIS B . n 
B 1 239 GLU 239 239 239 GLU GLU B . n 
B 1 240 GLY 240 240 240 GLY GLY B . n 
B 1 241 GLY 241 241 241 GLY GLY B . n 
B 1 242 ASN 242 242 242 ASN ASN B . n 
B 1 243 VAL 243 243 243 VAL VAL B . n 
B 1 244 SER 244 244 244 SER SER B . n 
B 1 245 ALA 245 245 245 ALA ALA B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 THR 247 247 247 THR THR B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 VAL 251 251 251 VAL VAL B . n 
B 1 252 ASN 252 252 252 ASN ASN B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 ALA 254 254 254 ALA ALA B . n 
B 1 255 TYR 255 255 255 TYR TYR B . n 
B 1 256 SER 256 256 256 SER SER B . n 
B 1 257 ASP 257 257 257 ASP ASP B . n 
B 1 258 ILE 258 258 258 ILE ILE B . n 
B 1 259 TYR 259 259 259 TYR TYR B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 SER 261 261 261 SER SER B . n 
B 1 262 PHE 262 262 262 PHE PHE B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 ALA 264 264 264 ALA ALA B . n 
B 1 265 ALA 265 265 265 ALA ALA B . n 
B 1 266 MET 266 266 266 MET MET B . n 
B 1 267 ASN 267 267 267 ASN ASN B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 LEU 269 269 269 LEU LEU B . n 
B 1 270 ALA 270 270 270 ALA ALA B . n 
B 1 271 GLY 271 271 271 GLY GLY B . n 
B 1 272 PRO 272 272 272 PRO PRO B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 HIS 274 274 274 HIS HIS B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 LEU 276 276 276 LEU LEU B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 ASN 278 278 278 ASN ASN B . n 
B 1 279 GLN 279 279 279 GLN GLN B . n 
B 1 280 GLU 280 280 280 GLU GLU B . n 
B 1 281 VAL 281 281 281 VAL VAL B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 ARG 283 283 283 ARG ARG B . n 
B 1 284 TRP 284 284 284 TRP TRP B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 GLN 286 286 286 GLN GLN B . n 
B 1 287 MET 287 287 287 MET MET B . n 
B 1 288 LEU 288 288 288 LEU LEU B . n 
B 1 289 TYR 289 289 289 TYR TYR B . n 
B 1 290 LYS 290 290 290 LYS LYS B . n 
B 1 291 LYS 291 291 291 LYS LYS B . n 
B 1 292 PHE 292 292 292 PHE PHE B . n 
B 1 293 GLY 293 293 293 GLY GLY B . n 
B 1 294 GLY 294 294 294 GLY GLY B . n 
B 1 295 VAL 295 295 295 VAL VAL B . n 
B 1 296 PRO 296 296 296 PRO PRO B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 LYS 298 298 298 LYS LYS B . n 
B 1 299 GLU 299 299 299 GLU GLU B . n 
B 1 300 GLN 300 300 300 GLN GLN B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 GLU 302 302 302 GLU GLU B . n 
B 1 303 ARG 303 303 303 ARG ARG B . n 
B 1 304 PHE 304 304 304 PHE PHE B . n 
B 1 305 ALA 305 305 305 ALA ALA B . n 
B 1 306 TRP 306 306 306 TRP TRP B . n 
B 1 307 ASP 307 307 307 ASP ASP B . n 
B 1 308 THR 308 308 308 THR THR B . n 
B 1 309 LEU 309 309 309 LEU LEU B . n 
B 1 310 ASN 310 310 310 ASN ASN B . n 
B 1 311 SER 311 311 311 SER SER B . n 
B 1 312 GLY 312 312 312 GLY GLY B . n 
B 1 313 GLN 313 313 313 GLN GLN B . n 
B 1 314 VAL 314 314 314 VAL VAL B . n 
B 1 315 ILE 315 315 315 ILE ILE B . n 
B 1 316 PRO 316 316 316 PRO PRO B . n 
B 1 317 GLY 317 317 317 GLY GLY B . n 
B 1 318 TYR 318 318 318 TYR TYR B . n 
B 1 319 GLY 319 319 319 GLY GLY B . n 
B 1 320 HIS 320 320 320 HIS HIS B . n 
B 1 321 ALA 321 321 321 ALA ALA B . n 
B 1 322 VAL 322 322 322 VAL VAL B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 ARG 324 324 324 ARG ARG B . n 
B 1 325 VAL 325 325 325 VAL VAL B . n 
B 1 326 THR 326 326 326 THR THR B . n 
B 1 327 ASP 327 327 327 ASP ASP B . n 
B 1 328 PRO 328 328 328 PRO PRO B . n 
B 1 329 ARG 329 329 329 ARG ARG B . n 
B 1 330 TYR 330 330 330 TYR TYR B . n 
B 1 331 VAL 331 331 331 VAL VAL B . n 
B 1 332 ALA 332 332 332 ALA ALA B . n 
B 1 333 GLN 333 333 333 GLN GLN B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 ASP 335 335 335 ASP ASP B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 LEU 338 338 338 LEU LEU B . n 
B 1 339 LYS 339 339 339 LYS LYS B . n 
B 1 340 HIS 340 340 340 HIS HIS B . n 
B 1 341 LEU 341 341 341 LEU LEU B . n 
B 1 342 PRO 342 342 342 PRO PRO B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 ASP 344 344 344 ASP ASP B . n 
B 1 345 GLU 345 345 345 GLU GLU B . n 
B 1 346 LEU 346 346 346 LEU LEU B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 LYS 348 348 348 LYS LYS B . n 
B 1 349 ILE 349 349 349 ILE ILE B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 SER 351 351 351 SER SER B . n 
B 1 352 LEU 352 352 352 LEU LEU B . n 
B 1 353 CYS 353 353 353 CYS CYS B . n 
B 1 354 TYR 354 354 354 TYR TYR B . n 
B 1 355 GLU 355 355 355 GLU GLU B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 ILE 357 357 357 ILE ILE B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 GLU 359 359 359 GLU GLU B . n 
B 1 360 VAL 360 360 360 VAL VAL B . n 
B 1 361 LEU 361 361 361 LEU LEU B . n 
B 1 362 LYS 362 362 362 LYS LYS B . n 
B 1 363 LYS 363 363 363 LYS LYS B . n 
B 1 364 HIS 364 364 364 HIS HIS B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 LYS 366 366 366 LYS LYS B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 LYS 368 368 368 LYS LYS B . n 
B 1 369 ASN 369 369 369 ASN ASN B . n 
B 1 370 PRO 370 370 370 PRO PRO B . n 
B 1 371 TRP 371 371 371 TRP TRP B . n 
B 1 372 PRO 372 372 372 PRO PRO B . n 
B 1 373 ASN 373 373 373 ASN ASN B . n 
B 1 374 VAL 374 374 374 VAL VAL B . n 
B 1 375 ASP 375 375 375 ASP ASP B . n 
B 1 376 ALA 376 376 376 ALA ALA B . n 
B 1 377 HIS 377 377 377 HIS HIS B . n 
B 1 378 SER 378 378 378 SER SER B . n 
B 1 379 GLY 379 379 379 GLY GLY B . n 
B 1 380 VAL 380 380 380 VAL VAL B . n 
B 1 381 LEU 381 381 381 LEU LEU B . n 
B 1 382 LEU 382 382 382 LEU LEU B . n 
B 1 383 TRP 383 383 383 TRP TRP B . n 
B 1 384 HIS 384 384 384 HIS HIS B . n 
B 1 385 TYR 385 385 385 TYR TYR B . n 
B 1 386 GLY 386 386 386 GLY GLY B . n 
B 1 387 ILE 387 387 387 ILE ILE B . n 
B 1 388 ARG 388 388 388 ARG ARG B . n 
B 1 389 GLU 389 389 389 GLU GLU B . n 
B 1 390 TYR 390 390 390 TYR TYR B . n 
B 1 391 ASP 391 391 391 ASP ASP B . n 
B 1 392 PHE 392 392 392 PHE PHE B . n 
B 1 393 TYR 393 393 393 TYR TYR B . n 
B 1 394 THR 394 394 394 THR THR B . n 
B 1 395 VAL 395 395 395 VAL VAL B . n 
B 1 396 LEU 396 396 396 LEU LEU B . n 
B 1 397 PHE 397 397 397 PHE PHE B . n 
B 1 398 GLY 398 398 398 GLY GLY B . n 
B 1 399 VAL 399 399 399 VAL VAL B . n 
B 1 400 SER 400 400 400 SER SER B . n 
B 1 401 ARG 401 401 401 ARG ARG B . n 
B 1 402 ALA 402 402 402 ALA ALA B . n 
B 1 403 LEU 403 403 403 LEU LEU B . n 
B 1 404 GLY 404 404 404 GLY GLY B . n 
B 1 405 CYS 405 405 405 CYS CYS B . n 
B 1 406 THR 406 406 406 THR THR B . n 
B 1 407 ALA 407 407 407 ALA ALA B . n 
B 1 408 GLN 408 408 408 GLN GLN B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 ILE 410 410 410 ILE ILE B . n 
B 1 411 LEU 411 411 411 LEU LEU B . n 
B 1 412 VAL 412 412 412 VAL VAL B . n 
B 1 413 ARG 413 413 413 ARG ARG B . n 
B 1 414 GLY 414 414 414 GLY GLY B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 MET 416 416 416 MET MET B . n 
B 1 417 LEU 417 417 417 LEU LEU B . n 
B 1 418 PRO 418 418 418 PRO PRO B . n 
B 1 419 ILE 419 419 419 ILE ILE B . n 
B 1 420 GLU 420 420 420 GLU GLU B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 PRO 422 422 422 PRO PRO B . n 
B 1 423 LYS 423 423 423 LYS LYS B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 ILE 425 425 425 ILE ILE B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 THR 427 427 427 THR THR B . n 
B 1 428 ARG 428 428 428 ARG ARG B . n 
B 1 429 TRP 429 429 429 TRP TRP B . n 
B 1 430 VAL 430 430 430 VAL VAL B . n 
B 1 431 LYS 431 431 431 LYS LYS B . n 
B 1 432 GLU 432 432 432 GLU GLU B . n 
B 1 433 VAL 433 433 433 VAL VAL B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 GLU 435 435 435 GLU GLU B . n 
B 1 436 SER 436 436 436 SER SER B . n 
B 1 437 LEU 437 437 437 LEU LEU B . n 
B 1 438 PRO 438 438 438 PRO PRO B . n 
B 1 439 VAL 439 439 439 VAL VAL B . n 
B 1 440 ALA 440 440 440 ALA ALA B . n 
B 1 441 GLY 441 441 441 GLY GLY B . n 
B 1 442 SER 442 442 442 SER SER B . n 
B 1 443 LYS 443 443 443 LYS LYS B . n 
B 1 444 LEU 444 444 444 LEU LEU B . n 
B 1 445 ALA 445 445 445 ALA ALA B . n 
B 1 446 ALA 446 446 446 ALA ALA B . n 
B 1 447 ALA 447 447 447 ALA ALA B . n 
B 1 448 LEU 448 448 448 LEU LEU B . n 
B 1 449 GLU 449 449 449 GLU GLU B . n 
C 1 1   MET 1   1   1   MET MET C . n 
C 1 2   LYS 2   2   2   LYS LYS C . n 
C 1 3   LEU 3   3   3   LEU LEU C . n 
C 1 4   LYS 4   4   4   LYS LYS C . n 
C 1 5   GLU 5   5   5   GLU GLU C . n 
C 1 6   ARG 6   6   6   ARG ARG C . n 
C 1 7   LEU 7   7   7   LEU LEU C . n 
C 1 8   ALA 8   8   8   ALA ALA C . n 
C 1 9   GLU 9   9   9   GLU GLU C . n 
C 1 10  LEU 10  10  10  LEU LEU C . n 
C 1 11  ILE 11  11  11  ILE ILE C . n 
C 1 12  PRO 12  12  12  PRO PRO C . n 
C 1 13  GLN 13  13  13  GLN GLN C . n 
C 1 14  TRP 14  14  14  TRP TRP C . n 
C 1 15  ARG 15  15  15  ARG ARG C . n 
C 1 16  ALA 16  16  16  ALA ALA C . n 
C 1 17  GLU 17  17  17  GLU GLU C . n 
C 1 18  VAL 18  18  18  VAL VAL C . n 
C 1 19  ALA 19  19  19  ALA ALA C . n 
C 1 20  GLU 20  20  20  GLU GLU C . n 
C 1 21  ILE 21  21  21  ILE ILE C . n 
C 1 22  ARG 22  22  22  ARG ARG C . n 
C 1 23  LYS 23  23  23  LYS LYS C . n 
C 1 24  LYS 24  24  24  LYS LYS C . n 
C 1 25  TYR 25  25  25  TYR TYR C . n 
C 1 26  GLY 26  26  26  GLY GLY C . n 
C 1 27  ASN 27  27  27  ASN ASN C . n 
C 1 28  ARG 28  28  28  ARG ARG C . n 
C 1 29  LYS 29  29  29  LYS LYS C . n 
C 1 30  THR 30  30  30  THR THR C . n 
C 1 31  MET 31  31  31  MET MET C . n 
C 1 32  ASP 32  32  32  ASP ASP C . n 
C 1 33  CYS 33  33  33  CYS CYS C . n 
C 1 34  THR 34  34  34  THR THR C . n 
C 1 35  ILE 35  35  35  ILE ILE C . n 
C 1 36  GLY 36  36  36  GLY GLY C . n 
C 1 37  HIS 37  37  37  HIS HIS C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  TYR 39  39  39  TYR TYR C . n 
C 1 40  GLY 40  40  40  GLY GLY C . n 
C 1 41  GLY 41  41  41  GLY GLY C . n 
C 1 42  MET 42  42  42  MET MET C . n 
C 1 43  ARG 43  43  43  ARG ARG C . n 
C 1 44  GLY 44  44  44  GLY GLY C . n 
C 1 45  LEU 45  45  45  LEU LEU C . n 
C 1 46  LYS 46  46  46  LYS LYS C . n 
C 1 47  ALA 47  47  47  ALA ALA C . n 
C 1 48  LEU 48  48  48  LEU LEU C . n 
C 1 49  VAL 49  49  49  VAL VAL C . n 
C 1 50  CYS 50  50  50  CYS CYS C . n 
C 1 51  ASP 51  51  51  ASP ASP C . n 
C 1 52  THR 52  52  52  THR THR C . n 
C 1 53  SER 53  53  53  SER SER C . n 
C 1 54  GLU 54  54  54  GLU GLU C . n 
C 1 55  VAL 55  55  55  VAL VAL C . n 
C 1 56  PHE 56  56  56  PHE PHE C . n 
C 1 57  PRO 57  57  57  PRO PRO C . n 
C 1 58  ASP 58  58  58  ASP ASP C . n 
C 1 59  GLU 59  59  59  GLU GLU C . n 
C 1 60  GLY 60  60  60  GLY GLY C . n 
C 1 61  VAL 61  61  61  VAL VAL C . n 
C 1 62  LYS 62  62  62  LYS LYS C . n 
C 1 63  PHE 63  63  63  PHE PHE C . n 
C 1 64  ARG 64  64  64  ARG ARG C . n 
C 1 65  GLY 65  65  65  GLY GLY C . n 
C 1 66  TYR 66  66  66  TYR TYR C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  ILE 68  68  68  ILE ILE C . n 
C 1 69  PRO 69  69  69  PRO PRO C . n 
C 1 70  GLU 70  70  70  GLU GLU C . n 
C 1 71  LEU 71  71  71  LEU LEU C . n 
C 1 72  ARG 72  72  72  ARG ARG C . n 
C 1 73  GLU 73  73  73  GLU GLU C . n 
C 1 74  GLY 74  74  74  GLY GLY C . n 
C 1 75  PRO 75  75  75  PRO PRO C . n 
C 1 76  HIS 76  76  76  HIS HIS C . n 
C 1 77  LYS 77  77  77  LYS LYS C . n 
C 1 78  LEU 78  78  78  LEU LEU C . n 
C 1 79  PRO 79  79  79  PRO PRO C . n 
C 1 80  THR 80  80  80  THR THR C . n 
C 1 81  ALA 81  81  81  ALA ALA C . n 
C 1 82  GLU 82  82  82  GLU GLU C . n 
C 1 83  GLY 83  83  83  GLY GLY C . n 
C 1 84  GLY 84  84  84  GLY GLY C . n 
C 1 85  PHE 85  85  85  PHE PHE C . n 
C 1 86  GLU 86  86  86  GLU GLU C . n 
C 1 87  PRO 87  87  87  PRO PRO C . n 
C 1 88  LEU 88  88  88  LEU LEU C . n 
C 1 89  PRO 89  89  89  PRO PRO C . n 
C 1 90  GLU 90  90  90  GLU GLU C . n 
C 1 91  GLY 91  91  91  GLY GLY C . n 
C 1 92  LEU 92  92  92  LEU LEU C . n 
C 1 93  TRP 93  93  93  TRP TRP C . n 
C 1 94  TYR 94  94  94  TYR TYR C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  LEU 96  96  96  LEU LEU C . n 
C 1 97  LEU 97  97  97  LEU LEU C . n 
C 1 98  THR 98  98  98  THR THR C . n 
C 1 99  GLY 99  99  99  GLY GLY C . n 
C 1 100 GLU 100 100 100 GLU GLU C . n 
C 1 101 LEU 101 101 101 LEU LEU C . n 
C 1 102 PRO 102 102 102 PRO PRO C . n 
C 1 103 THR 103 103 103 THR THR C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 GLU 105 105 105 GLU GLU C . n 
C 1 106 ASP 106 106 106 ASP ASP C . n 
C 1 107 VAL 107 107 107 VAL VAL C . n 
C 1 108 LYS 108 108 108 LYS LYS C . n 
C 1 109 GLU 109 109 109 GLU GLU C . n 
C 1 110 ILE 110 110 110 ILE ILE C . n 
C 1 111 SER 111 111 111 SER SER C . n 
C 1 112 ALA 112 112 112 ALA ALA C . n 
C 1 113 GLU 113 113 113 GLU GLU C . n 
C 1 114 PHE 114 114 114 PHE PHE C . n 
C 1 115 THR 115 115 115 THR THR C . n 
C 1 116 LYS 116 116 116 LYS LYS C . n 
C 1 117 ARG 117 117 117 ARG ARG C . n 
C 1 118 MET 118 118 118 MET MET C . n 
C 1 119 GLN 119 119 119 GLN GLN C . n 
C 1 120 ASN 120 120 120 ASN ASN C . n 
C 1 121 VAL 121 121 121 VAL VAL C . n 
C 1 122 PRO 122 122 122 PRO PRO C . n 
C 1 123 GLN 123 123 123 GLN GLN C . n 
C 1 124 TYR 124 124 124 TYR TYR C . n 
C 1 125 VAL 125 125 125 VAL VAL C . n 
C 1 126 PHE 126 126 126 PHE PHE C . n 
C 1 127 ASP 127 127 127 ASP ASP C . n 
C 1 128 VAL 128 128 128 VAL VAL C . n 
C 1 129 LEU 129 129 129 LEU LEU C . n 
C 1 130 ARG 130 130 130 ARG ARG C . n 
C 1 131 ALA 131 131 131 ALA ALA C . n 
C 1 132 MET 132 132 132 MET MET C . n 
C 1 133 PRO 133 133 133 PRO PRO C . n 
C 1 134 VAL 134 134 134 VAL VAL C . n 
C 1 135 ASP 135 135 135 ASP ASP C . n 
C 1 136 THR 136 136 136 THR THR C . n 
C 1 137 HIS 137 137 137 HIS HIS C . n 
C 1 138 PRO 138 138 138 PRO PRO C . n 
C 1 139 MET 139 139 139 MET MET C . n 
C 1 140 THR 140 140 140 THR THR C . n 
C 1 141 MET 141 141 141 MET MET C . n 
C 1 142 PHE 142 142 142 PHE PHE C . n 
C 1 143 ALA 143 143 143 ALA ALA C . n 
C 1 144 ALA 144 144 144 ALA ALA C . n 
C 1 145 GLY 145 145 145 GLY GLY C . n 
C 1 146 ILE 146 146 146 ILE ILE C . n 
C 1 147 LEU 147 147 147 LEU LEU C . n 
C 1 148 ALA 148 148 148 ALA ALA C . n 
C 1 149 MET 149 149 149 MET MET C . n 
C 1 150 GLN 150 150 150 GLN GLN C . n 
C 1 151 ARG 151 151 151 ARG ARG C . n 
C 1 152 GLU 152 152 152 GLU GLU C . n 
C 1 153 SER 153 153 153 SER SER C . n 
C 1 154 VAL 154 154 154 VAL VAL C . n 
C 1 155 PHE 155 155 155 PHE PHE C . n 
C 1 156 ALA 156 156 156 ALA ALA C . n 
C 1 157 LYS 157 157 157 LYS LYS C . n 
C 1 158 ARG 158 158 158 ARG ARG C . n 
C 1 159 TYR 159 159 159 TYR TYR C . n 
C 1 160 GLU 160 160 160 GLU GLU C . n 
C 1 161 GLU 161 161 161 GLU GLU C . n 
C 1 162 GLY 162 162 162 GLY GLY C . n 
C 1 163 MET 163 163 163 MET MET C . n 
C 1 164 ARG 164 164 164 ARG ARG C . n 
C 1 165 ARG 165 165 165 ARG ARG C . n 
C 1 166 GLU 166 166 166 GLU GLU C . n 
C 1 167 GLU 167 167 167 GLU GLU C . n 
C 1 168 HIS 168 168 168 HIS HIS C . n 
C 1 169 TRP 169 169 169 TRP TRP C . n 
C 1 170 GLU 170 170 170 GLU GLU C . n 
C 1 171 ALA 171 171 171 ALA ALA C . n 
C 1 172 MET 172 172 172 MET MET C . n 
C 1 173 LEU 173 173 173 LEU LEU C . n 
C 1 174 GLU 174 174 174 GLU GLU C . n 
C 1 175 ASP 175 175 175 ASP ASP C . n 
C 1 176 SER 176 176 176 SER SER C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 ASN 178 178 178 ASN ASN C . n 
C 1 179 MET 179 179 179 MET MET C . n 
C 1 180 LEU 180 180 180 LEU LEU C . n 
C 1 181 ALA 181 181 181 ALA ALA C . n 
C 1 182 ALA 182 182 182 ALA ALA C . n 
C 1 183 LEU 183 183 183 LEU LEU C . n 
C 1 184 PRO 184 184 184 PRO PRO C . n 
C 1 185 VAL 185 185 185 VAL VAL C . n 
C 1 186 ILE 186 186 186 ILE ILE C . n 
C 1 187 ALA 187 187 187 ALA ALA C . n 
C 1 188 ALA 188 188 188 ALA ALA C . n 
C 1 189 TYR 189 189 189 TYR TYR C . n 
C 1 190 ILE 190 190 190 ILE ILE C . n 
C 1 191 TYR 191 191 191 TYR TYR C . n 
C 1 192 ARG 192 192 192 ARG ARG C . n 
C 1 193 ARG 193 193 193 ARG ARG C . n 
C 1 194 LYS 194 194 194 LYS LYS C . n 
C 1 195 TYR 195 195 195 TYR TYR C . n 
C 1 196 LYS 196 196 196 LYS LYS C . n 
C 1 197 GLY 197 197 197 GLY GLY C . n 
C 1 198 ASP 198 198 198 ASP ASP C . n 
C 1 199 THR 199 199 199 THR THR C . n 
C 1 200 HIS 200 200 200 HIS HIS C . n 
C 1 201 ILE 201 201 201 ILE ILE C . n 
C 1 202 ALA 202 202 202 ALA ALA C . n 
C 1 203 PRO 203 203 203 PRO PRO C . n 
C 1 204 ASP 204 204 204 ASP ASP C . n 
C 1 205 PRO 205 205 205 PRO PRO C . n 
C 1 206 ASN 206 206 206 ASN ASN C . n 
C 1 207 LEU 207 207 207 LEU LEU C . n 
C 1 208 ASP 208 208 208 ASP ASP C . n 
C 1 209 TRP 209 209 209 TRP TRP C . n 
C 1 210 SER 210 210 210 SER SER C . n 
C 1 211 ALA 211 211 211 ALA ALA C . n 
C 1 212 ASN 212 212 212 ASN ASN C . n 
C 1 213 LEU 213 213 213 LEU LEU C . n 
C 1 214 ALA 214 214 214 ALA ALA C . n 
C 1 215 HIS 215 215 215 HIS HIS C . n 
C 1 216 MET 216 216 216 MET MET C . n 
C 1 217 MET 217 217 217 MET MET C . n 
C 1 218 GLY 218 218 218 GLY GLY C . n 
C 1 219 PHE 219 219 219 PHE PHE C . n 
C 1 220 ASP 220 220 220 ASP ASP C . n 
C 1 221 ASP 221 221 221 ASP ASP C . n 
C 1 222 PHE 222 222 222 PHE PHE C . n 
C 1 223 GLU 223 223 223 GLU GLU C . n 
C 1 224 VAL 224 224 224 VAL VAL C . n 
C 1 225 TYR 225 225 225 TYR TYR C . n 
C 1 226 GLU 226 226 226 GLU GLU C . n 
C 1 227 LEU 227 227 227 LEU LEU C . n 
C 1 228 PHE 228 228 228 PHE PHE C . n 
C 1 229 ARG 229 229 229 ARG ARG C . n 
C 1 230 LEU 230 230 230 LEU LEU C . n 
C 1 231 TYR 231 231 231 TYR TYR C . n 
C 1 232 MET 232 232 232 MET MET C . n 
C 1 233 PHE 233 233 233 PHE PHE C . n 
C 1 234 LEU 234 234 234 LEU LEU C . n 
C 1 235 HIS 235 235 235 HIS HIS C . n 
C 1 236 SER 236 236 236 SER SER C . n 
C 1 237 ASP 237 237 237 ASP ASP C . n 
C 1 238 HIS 238 238 238 HIS HIS C . n 
C 1 239 GLU 239 239 239 GLU GLU C . n 
C 1 240 GLY 240 240 240 GLY GLY C . n 
C 1 241 GLY 241 241 241 GLY GLY C . n 
C 1 242 ASN 242 242 242 ASN ASN C . n 
C 1 243 VAL 243 243 243 VAL VAL C . n 
C 1 244 SER 244 244 244 SER SER C . n 
C 1 245 ALA 245 245 245 ALA ALA C . n 
C 1 246 HIS 246 246 246 HIS HIS C . n 
C 1 247 THR 247 247 247 THR THR C . n 
C 1 248 ASN 248 248 248 ASN ASN C . n 
C 1 249 LEU 249 249 249 LEU LEU C . n 
C 1 250 LEU 250 250 250 LEU LEU C . n 
C 1 251 VAL 251 251 251 VAL VAL C . n 
C 1 252 ASN 252 252 252 ASN ASN C . n 
C 1 253 SER 253 253 253 SER SER C . n 
C 1 254 ALA 254 254 254 ALA ALA C . n 
C 1 255 TYR 255 255 255 TYR TYR C . n 
C 1 256 SER 256 256 256 SER SER C . n 
C 1 257 ASP 257 257 257 ASP ASP C . n 
C 1 258 ILE 258 258 258 ILE ILE C . n 
C 1 259 TYR 259 259 259 TYR TYR C . n 
C 1 260 ARG 260 260 260 ARG ARG C . n 
C 1 261 SER 261 261 261 SER SER C . n 
C 1 262 PHE 262 262 262 PHE PHE C . n 
C 1 263 SER 263 263 263 SER SER C . n 
C 1 264 ALA 264 264 264 ALA ALA C . n 
C 1 265 ALA 265 265 265 ALA ALA C . n 
C 1 266 MET 266 266 266 MET MET C . n 
C 1 267 ASN 267 267 267 ASN ASN C . n 
C 1 268 GLY 268 268 268 GLY GLY C . n 
C 1 269 LEU 269 269 269 LEU LEU C . n 
C 1 270 ALA 270 270 270 ALA ALA C . n 
C 1 271 GLY 271 271 271 GLY GLY C . n 
C 1 272 PRO 272 272 272 PRO PRO C . n 
C 1 273 LEU 273 273 273 LEU LEU C . n 
C 1 274 HIS 274 274 274 HIS HIS C . n 
C 1 275 GLY 275 275 275 GLY GLY C . n 
C 1 276 LEU 276 276 276 LEU LEU C . n 
C 1 277 ALA 277 277 277 ALA ALA C . n 
C 1 278 ASN 278 278 278 ASN ASN C . n 
C 1 279 GLN 279 279 279 GLN GLN C . n 
C 1 280 GLU 280 280 280 GLU GLU C . n 
C 1 281 VAL 281 281 281 VAL VAL C . n 
C 1 282 LEU 282 282 282 LEU LEU C . n 
C 1 283 ARG 283 283 283 ARG ARG C . n 
C 1 284 TRP 284 284 284 TRP TRP C . n 
C 1 285 ILE 285 285 285 ILE ILE C . n 
C 1 286 GLN 286 286 286 GLN GLN C . n 
C 1 287 MET 287 287 287 MET MET C . n 
C 1 288 LEU 288 288 288 LEU LEU C . n 
C 1 289 TYR 289 289 289 TYR TYR C . n 
C 1 290 LYS 290 290 290 LYS LYS C . n 
C 1 291 LYS 291 291 291 LYS LYS C . n 
C 1 292 PHE 292 292 292 PHE PHE C . n 
C 1 293 GLY 293 293 293 GLY GLY C . n 
C 1 294 GLY 294 294 294 GLY GLY C . n 
C 1 295 VAL 295 295 295 VAL VAL C . n 
C 1 296 PRO 296 296 296 PRO PRO C . n 
C 1 297 THR 297 297 297 THR THR C . n 
C 1 298 LYS 298 298 298 LYS LYS C . n 
C 1 299 GLU 299 299 299 GLU GLU C . n 
C 1 300 GLN 300 300 300 GLN GLN C . n 
C 1 301 LEU 301 301 301 LEU LEU C . n 
C 1 302 GLU 302 302 302 GLU GLU C . n 
C 1 303 ARG 303 303 303 ARG ARG C . n 
C 1 304 PHE 304 304 304 PHE PHE C . n 
C 1 305 ALA 305 305 305 ALA ALA C . n 
C 1 306 TRP 306 306 306 TRP TRP C . n 
C 1 307 ASP 307 307 307 ASP ASP C . n 
C 1 308 THR 308 308 308 THR THR C . n 
C 1 309 LEU 309 309 309 LEU LEU C . n 
C 1 310 ASN 310 310 310 ASN ASN C . n 
C 1 311 SER 311 311 311 SER SER C . n 
C 1 312 GLY 312 312 312 GLY GLY C . n 
C 1 313 GLN 313 313 313 GLN GLN C . n 
C 1 314 VAL 314 314 314 VAL VAL C . n 
C 1 315 ILE 315 315 315 ILE ILE C . n 
C 1 316 PRO 316 316 316 PRO PRO C . n 
C 1 317 GLY 317 317 317 GLY GLY C . n 
C 1 318 TYR 318 318 318 TYR TYR C . n 
C 1 319 GLY 319 319 319 GLY GLY C . n 
C 1 320 HIS 320 320 320 HIS HIS C . n 
C 1 321 ALA 321 321 321 ALA ALA C . n 
C 1 322 VAL 322 322 322 VAL VAL C . n 
C 1 323 LEU 323 323 323 LEU LEU C . n 
C 1 324 ARG 324 324 324 ARG ARG C . n 
C 1 325 VAL 325 325 325 VAL VAL C . n 
C 1 326 THR 326 326 326 THR THR C . n 
C 1 327 ASP 327 327 327 ASP ASP C . n 
C 1 328 PRO 328 328 328 PRO PRO C . n 
C 1 329 ARG 329 329 329 ARG ARG C . n 
C 1 330 TYR 330 330 330 TYR TYR C . n 
C 1 331 VAL 331 331 331 VAL VAL C . n 
C 1 332 ALA 332 332 332 ALA ALA C . n 
C 1 333 GLN 333 333 333 GLN GLN C . n 
C 1 334 ARG 334 334 334 ARG ARG C . n 
C 1 335 ASP 335 335 335 ASP ASP C . n 
C 1 336 PHE 336 336 336 PHE PHE C . n 
C 1 337 ALA 337 337 337 ALA ALA C . n 
C 1 338 LEU 338 338 338 LEU LEU C . n 
C 1 339 LYS 339 339 339 LYS LYS C . n 
C 1 340 HIS 340 340 340 HIS HIS C . n 
C 1 341 LEU 341 341 341 LEU LEU C . n 
C 1 342 PRO 342 342 342 PRO PRO C . n 
C 1 343 ASP 343 343 343 ASP ASP C . n 
C 1 344 ASP 344 344 344 ASP ASP C . n 
C 1 345 GLU 345 345 345 GLU GLU C . n 
C 1 346 LEU 346 346 346 LEU LEU C . n 
C 1 347 PHE 347 347 347 PHE PHE C . n 
C 1 348 LYS 348 348 348 LYS LYS C . n 
C 1 349 ILE 349 349 349 ILE ILE C . n 
C 1 350 VAL 350 350 350 VAL VAL C . n 
C 1 351 SER 351 351 351 SER SER C . n 
C 1 352 LEU 352 352 352 LEU LEU C . n 
C 1 353 CYS 353 353 353 CYS CYS C . n 
C 1 354 TYR 354 354 354 TYR TYR C . n 
C 1 355 GLU 355 355 355 GLU GLU C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 ILE 357 357 357 ILE ILE C . n 
C 1 358 PRO 358 358 358 PRO PRO C . n 
C 1 359 GLU 359 359 359 GLU GLU C . n 
C 1 360 VAL 360 360 360 VAL VAL C . n 
C 1 361 LEU 361 361 361 LEU LEU C . n 
C 1 362 LYS 362 362 362 LYS LYS C . n 
C 1 363 LYS 363 363 363 LYS LYS C . n 
C 1 364 HIS 364 364 364 HIS HIS C . n 
C 1 365 GLY 365 365 365 GLY GLY C . n 
C 1 366 LYS 366 366 366 LYS LYS C . n 
C 1 367 ALA 367 367 367 ALA ALA C . n 
C 1 368 LYS 368 368 368 LYS LYS C . n 
C 1 369 ASN 369 369 369 ASN ASN C . n 
C 1 370 PRO 370 370 370 PRO PRO C . n 
C 1 371 TRP 371 371 371 TRP TRP C . n 
C 1 372 PRO 372 372 372 PRO PRO C . n 
C 1 373 ASN 373 373 373 ASN ASN C . n 
C 1 374 VAL 374 374 374 VAL VAL C . n 
C 1 375 ASP 375 375 375 ASP ASP C . n 
C 1 376 ALA 376 376 376 ALA ALA C . n 
C 1 377 HIS 377 377 377 HIS HIS C . n 
C 1 378 SER 378 378 378 SER SER C . n 
C 1 379 GLY 379 379 379 GLY GLY C . n 
C 1 380 VAL 380 380 380 VAL VAL C . n 
C 1 381 LEU 381 381 381 LEU LEU C . n 
C 1 382 LEU 382 382 382 LEU LEU C . n 
C 1 383 TRP 383 383 383 TRP TRP C . n 
C 1 384 HIS 384 384 384 HIS HIS C . n 
C 1 385 TYR 385 385 385 TYR TYR C . n 
C 1 386 GLY 386 386 386 GLY GLY C . n 
C 1 387 ILE 387 387 387 ILE ILE C . n 
C 1 388 ARG 388 388 388 ARG ARG C . n 
C 1 389 GLU 389 389 389 GLU GLU C . n 
C 1 390 TYR 390 390 390 TYR TYR C . n 
C 1 391 ASP 391 391 391 ASP ASP C . n 
C 1 392 PHE 392 392 392 PHE PHE C . n 
C 1 393 TYR 393 393 393 TYR TYR C . n 
C 1 394 THR 394 394 394 THR THR C . n 
C 1 395 VAL 395 395 395 VAL VAL C . n 
C 1 396 LEU 396 396 396 LEU LEU C . n 
C 1 397 PHE 397 397 397 PHE PHE C . n 
C 1 398 GLY 398 398 398 GLY GLY C . n 
C 1 399 VAL 399 399 399 VAL VAL C . n 
C 1 400 SER 400 400 400 SER SER C . n 
C 1 401 ARG 401 401 401 ARG ARG C . n 
C 1 402 ALA 402 402 402 ALA ALA C . n 
C 1 403 LEU 403 403 403 LEU LEU C . n 
C 1 404 GLY 404 404 404 GLY GLY C . n 
C 1 405 CYS 405 405 405 CYS CYS C . n 
C 1 406 THR 406 406 406 THR THR C . n 
C 1 407 ALA 407 407 407 ALA ALA C . n 
C 1 408 GLN 408 408 408 GLN GLN C . n 
C 1 409 ALA 409 409 409 ALA ALA C . n 
C 1 410 ILE 410 410 410 ILE ILE C . n 
C 1 411 LEU 411 411 411 LEU LEU C . n 
C 1 412 VAL 412 412 412 VAL VAL C . n 
C 1 413 ARG 413 413 413 ARG ARG C . n 
C 1 414 GLY 414 414 414 GLY GLY C . n 
C 1 415 TYR 415 415 415 TYR TYR C . n 
C 1 416 MET 416 416 416 MET MET C . n 
C 1 417 LEU 417 417 417 LEU LEU C . n 
C 1 418 PRO 418 418 418 PRO PRO C . n 
C 1 419 ILE 419 419 419 ILE ILE C . n 
C 1 420 GLU 420 420 420 GLU GLU C . n 
C 1 421 ARG 421 421 421 ARG ARG C . n 
C 1 422 PRO 422 422 422 PRO PRO C . n 
C 1 423 LYS 423 423 423 LYS LYS C . n 
C 1 424 SER 424 424 424 SER SER C . n 
C 1 425 ILE 425 425 425 ILE ILE C . n 
C 1 426 THR 426 426 426 THR THR C . n 
C 1 427 THR 427 427 427 THR THR C . n 
C 1 428 ARG 428 428 428 ARG ARG C . n 
C 1 429 TRP 429 429 429 TRP TRP C . n 
C 1 430 VAL 430 430 430 VAL VAL C . n 
C 1 431 LYS 431 431 431 LYS LYS C . n 
C 1 432 GLU 432 432 432 GLU GLU C . n 
C 1 433 VAL 433 433 433 VAL VAL C . n 
C 1 434 ALA 434 434 434 ALA ALA C . n 
C 1 435 GLU 435 435 435 GLU GLU C . n 
C 1 436 SER 436 436 436 SER SER C . n 
C 1 437 LEU 437 437 437 LEU LEU C . n 
C 1 438 PRO 438 438 438 PRO PRO C . n 
C 1 439 VAL 439 439 439 VAL VAL C . n 
C 1 440 ALA 440 440 440 ALA ALA C . n 
C 1 441 GLY 441 441 441 GLY GLY C . n 
C 1 442 SER 442 442 442 SER SER C . n 
C 1 443 LYS 443 443 ?   ?   ?   C . n 
C 1 444 LEU 444 444 ?   ?   ?   C . n 
C 1 445 ALA 445 445 ?   ?   ?   C . n 
C 1 446 ALA 446 446 ?   ?   ?   C . n 
C 1 447 ALA 447 447 ?   ?   ?   C . n 
C 1 448 LEU 448 448 ?   ?   ?   C . n 
C 1 449 GLU 449 449 ?   ?   ?   C . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 CIT ? ? CIT ? ? 'SUBJECT OF INVESTIGATION' ? 
2 COA ? ? COA ? ? 'SUBJECT OF INVESTIGATION' ? 
3 OAA ? ? OAA ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 COA 1  501 502 COA COA A . 
E 3 OAA 1  502 503 OAA OAA A . 
F 3 OAA 1  501 501 OAA OAA B . 
G 2 COA 1  501 502 COA COA C . 
H 4 CIT 1  502 503 CIT CIT C . 
I 5 HOH 1  601 168 HOH HOH A . 
I 5 HOH 2  602 130 HOH HOH A . 
I 5 HOH 3  603 82  HOH HOH A . 
I 5 HOH 4  604 122 HOH HOH A . 
I 5 HOH 5  605 29  HOH HOH A . 
I 5 HOH 6  606 47  HOH HOH A . 
I 5 HOH 7  607 81  HOH HOH A . 
I 5 HOH 8  608 212 HOH HOH A . 
I 5 HOH 9  609 46  HOH HOH A . 
I 5 HOH 10 610 244 HOH HOH A . 
I 5 HOH 11 611 143 HOH HOH A . 
I 5 HOH 12 612 174 HOH HOH A . 
I 5 HOH 13 613 37  HOH HOH A . 
I 5 HOH 14 614 126 HOH HOH A . 
I 5 HOH 15 615 118 HOH HOH A . 
I 5 HOH 16 616 5   HOH HOH A . 
I 5 HOH 17 617 190 HOH HOH A . 
I 5 HOH 18 618 19  HOH HOH A . 
I 5 HOH 19 619 100 HOH HOH A . 
I 5 HOH 20 620 79  HOH HOH A . 
I 5 HOH 21 621 116 HOH HOH A . 
I 5 HOH 22 622 84  HOH HOH A . 
I 5 HOH 23 623 113 HOH HOH A . 
I 5 HOH 24 624 7   HOH HOH A . 
I 5 HOH 25 625 255 HOH HOH A . 
I 5 HOH 26 626 20  HOH HOH A . 
I 5 HOH 27 627 240 HOH HOH A . 
I 5 HOH 28 628 35  HOH HOH A . 
I 5 HOH 29 629 62  HOH HOH A . 
I 5 HOH 30 630 25  HOH HOH A . 
I 5 HOH 31 631 73  HOH HOH A . 
I 5 HOH 32 632 198 HOH HOH A . 
I 5 HOH 33 633 21  HOH HOH A . 
I 5 HOH 34 634 256 HOH HOH A . 
I 5 HOH 35 635 245 HOH HOH A . 
I 5 HOH 36 636 13  HOH HOH A . 
I 5 HOH 37 637 90  HOH HOH A . 
I 5 HOH 38 638 15  HOH HOH A . 
I 5 HOH 39 639 107 HOH HOH A . 
I 5 HOH 40 640 95  HOH HOH A . 
I 5 HOH 41 641 30  HOH HOH A . 
I 5 HOH 42 642 3   HOH HOH A . 
I 5 HOH 43 643 125 HOH HOH A . 
I 5 HOH 44 644 110 HOH HOH A . 
I 5 HOH 45 645 153 HOH HOH A . 
I 5 HOH 46 646 194 HOH HOH A . 
I 5 HOH 47 647 136 HOH HOH A . 
I 5 HOH 48 648 59  HOH HOH A . 
I 5 HOH 49 649 199 HOH HOH A . 
I 5 HOH 50 650 227 HOH HOH A . 
I 5 HOH 51 651 214 HOH HOH A . 
I 5 HOH 52 652 163 HOH HOH A . 
I 5 HOH 53 653 191 HOH HOH A . 
I 5 HOH 54 654 124 HOH HOH A . 
I 5 HOH 55 655 26  HOH HOH A . 
I 5 HOH 56 656 181 HOH HOH A . 
I 5 HOH 57 657 92  HOH HOH A . 
I 5 HOH 58 658 210 HOH HOH A . 
I 5 HOH 59 659 38  HOH HOH A . 
I 5 HOH 60 660 119 HOH HOH A . 
I 5 HOH 61 661 97  HOH HOH A . 
I 5 HOH 62 662 175 HOH HOH A . 
I 5 HOH 63 663 195 HOH HOH A . 
J 5 HOH 1  601 58  HOH HOH B . 
J 5 HOH 2  602 196 HOH HOH B . 
J 5 HOH 3  603 22  HOH HOH B . 
J 5 HOH 4  604 12  HOH HOH B . 
J 5 HOH 5  605 24  HOH HOH B . 
J 5 HOH 6  606 85  HOH HOH B . 
J 5 HOH 7  607 115 HOH HOH B . 
J 5 HOH 8  608 182 HOH HOH B . 
J 5 HOH 9  609 230 HOH HOH B . 
J 5 HOH 10 610 34  HOH HOH B . 
J 5 HOH 11 611 10  HOH HOH B . 
J 5 HOH 12 612 137 HOH HOH B . 
J 5 HOH 13 613 48  HOH HOH B . 
J 5 HOH 14 614 60  HOH HOH B . 
J 5 HOH 15 615 55  HOH HOH B . 
J 5 HOH 16 616 121 HOH HOH B . 
J 5 HOH 17 617 2   HOH HOH B . 
J 5 HOH 18 618 43  HOH HOH B . 
J 5 HOH 19 619 4   HOH HOH B . 
J 5 HOH 20 620 65  HOH HOH B . 
J 5 HOH 21 621 149 HOH HOH B . 
J 5 HOH 22 622 86  HOH HOH B . 
J 5 HOH 23 623 98  HOH HOH B . 
J 5 HOH 24 624 99  HOH HOH B . 
J 5 HOH 25 625 63  HOH HOH B . 
J 5 HOH 26 626 71  HOH HOH B . 
J 5 HOH 27 627 53  HOH HOH B . 
J 5 HOH 28 628 232 HOH HOH B . 
J 5 HOH 29 629 114 HOH HOH B . 
J 5 HOH 30 630 75  HOH HOH B . 
J 5 HOH 31 631 51  HOH HOH B . 
J 5 HOH 32 632 76  HOH HOH B . 
J 5 HOH 33 633 156 HOH HOH B . 
J 5 HOH 34 634 89  HOH HOH B . 
J 5 HOH 35 635 235 HOH HOH B . 
J 5 HOH 36 636 204 HOH HOH B . 
J 5 HOH 37 637 91  HOH HOH B . 
J 5 HOH 38 638 185 HOH HOH B . 
J 5 HOH 39 639 142 HOH HOH B . 
J 5 HOH 40 640 87  HOH HOH B . 
J 5 HOH 41 641 66  HOH HOH B . 
J 5 HOH 42 642 161 HOH HOH B . 
J 5 HOH 43 643 250 HOH HOH B . 
J 5 HOH 44 644 166 HOH HOH B . 
J 5 HOH 45 645 105 HOH HOH B . 
J 5 HOH 46 646 165 HOH HOH B . 
J 5 HOH 47 647 141 HOH HOH B . 
J 5 HOH 48 648 258 HOH HOH B . 
J 5 HOH 49 649 179 HOH HOH B . 
K 5 HOH 1  601 69  HOH HOH C . 
K 5 HOH 2  602 101 HOH HOH C . 
K 5 HOH 3  603 80  HOH HOH C . 
K 5 HOH 4  604 16  HOH HOH C . 
K 5 HOH 5  605 218 HOH HOH C . 
K 5 HOH 6  606 36  HOH HOH C . 
K 5 HOH 7  607 31  HOH HOH C . 
K 5 HOH 8  608 102 HOH HOH C . 
K 5 HOH 9  609 145 HOH HOH C . 
K 5 HOH 10 610 18  HOH HOH C . 
K 5 HOH 11 611 160 HOH HOH C . 
K 5 HOH 12 612 1   HOH HOH C . 
K 5 HOH 13 613 11  HOH HOH C . 
K 5 HOH 14 614 74  HOH HOH C . 
K 5 HOH 15 615 106 HOH HOH C . 
K 5 HOH 16 616 78  HOH HOH C . 
K 5 HOH 17 617 139 HOH HOH C . 
K 5 HOH 18 618 111 HOH HOH C . 
K 5 HOH 19 619 23  HOH HOH C . 
K 5 HOH 20 620 72  HOH HOH C . 
K 5 HOH 21 621 132 HOH HOH C . 
K 5 HOH 22 622 67  HOH HOH C . 
K 5 HOH 23 623 9   HOH HOH C . 
K 5 HOH 24 624 68  HOH HOH C . 
K 5 HOH 25 625 247 HOH HOH C . 
K 5 HOH 26 626 94  HOH HOH C . 
K 5 HOH 27 627 8   HOH HOH C . 
K 5 HOH 28 628 17  HOH HOH C . 
K 5 HOH 29 629 112 HOH HOH C . 
K 5 HOH 30 630 96  HOH HOH C . 
K 5 HOH 31 631 54  HOH HOH C . 
K 5 HOH 32 632 203 HOH HOH C . 
K 5 HOH 33 633 88  HOH HOH C . 
K 5 HOH 34 634 64  HOH HOH C . 
K 5 HOH 35 635 155 HOH HOH C . 
K 5 HOH 36 636 45  HOH HOH C . 
K 5 HOH 37 637 70  HOH HOH C . 
K 5 HOH 38 638 206 HOH HOH C . 
K 5 HOH 39 639 205 HOH HOH C . 
K 5 HOH 40 640 144 HOH HOH C . 
K 5 HOH 41 641 6   HOH HOH C . 
K 5 HOH 42 642 193 HOH HOH C . 
K 5 HOH 43 643 44  HOH HOH C . 
K 5 HOH 44 644 123 HOH HOH C . 
K 5 HOH 45 645 104 HOH HOH C . 
K 5 HOH 46 646 229 HOH HOH C . 
K 5 HOH 47 647 215 HOH HOH C . 
K 5 HOH 48 648 167 HOH HOH C . 
K 5 HOH 49 649 188 HOH HOH C . 
K 5 HOH 50 650 251 HOH HOH C . 
K 5 HOH 51 651 39  HOH HOH C . 
K 5 HOH 52 652 83  HOH HOH C . 
K 5 HOH 53 653 192 HOH HOH C . 
K 5 HOH 54 654 187 HOH HOH C . 
K 5 HOH 55 655 103 HOH HOH C . 
K 5 HOH 56 656 108 HOH HOH C . 
K 5 HOH 57 657 120 HOH HOH C . 
K 5 HOH 58 658 131 HOH HOH C . 
K 5 HOH 59 659 50  HOH HOH C . 
K 5 HOH 60 660 173 HOH HOH C . 
K 5 HOH 61 661 56  HOH HOH C . 
K 5 HOH 62 662 109 HOH HOH C . 
K 5 HOH 63 663 133 HOH HOH C . 
K 5 HOH 64 664 169 HOH HOH C . 
K 5 HOH 65 665 77  HOH HOH C . 
K 5 HOH 66 666 243 HOH HOH C . 
K 5 HOH 67 667 248 HOH HOH C . 
K 5 HOH 68 668 57  HOH HOH C . 
K 5 HOH 69 669 257 HOH HOH C . 
K 5 HOH 70 670 157 HOH HOH C . 
K 5 HOH 71 671 154 HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 368 ? CG  ? A LYS 368 CG  
2  1 Y 1 A LYS 368 ? CD  ? A LYS 368 CD  
3  1 Y 1 A LYS 368 ? CE  ? A LYS 368 CE  
4  1 Y 1 A LYS 368 ? NZ  ? A LYS 368 NZ  
5  1 Y 1 A LYS 443 ? CG  ? A LYS 443 CG  
6  1 Y 1 A LYS 443 ? CD  ? A LYS 443 CD  
7  1 Y 1 A LYS 443 ? CE  ? A LYS 443 CE  
8  1 Y 1 A LYS 443 ? NZ  ? A LYS 443 NZ  
9  1 Y 1 A LEU 448 ? CG  ? A LEU 448 CG  
10 1 Y 1 A LEU 448 ? CD1 ? A LEU 448 CD1 
11 1 Y 1 A LEU 448 ? CD2 ? A LEU 448 CD2 
12 1 Y 1 B LYS 368 ? CG  ? B LYS 368 CG  
13 1 Y 1 B LYS 368 ? CD  ? B LYS 368 CD  
14 1 Y 1 B LYS 368 ? CE  ? B LYS 368 CE  
15 1 Y 1 B LYS 368 ? NZ  ? B LYS 368 NZ  
16 1 Y 1 B LYS 443 ? CG  ? B LYS 443 CG  
17 1 Y 1 B LYS 443 ? CD  ? B LYS 443 CD  
18 1 Y 1 B LYS 443 ? CE  ? B LYS 443 CE  
19 1 Y 1 B LYS 443 ? NZ  ? B LYS 443 NZ  
20 1 Y 1 C LYS 368 ? CG  ? C LYS 368 CG  
21 1 Y 1 C LYS 368 ? CD  ? C LYS 368 CD  
22 1 Y 1 C LYS 368 ? CE  ? C LYS 368 CE  
23 1 Y 1 C LYS 368 ? NZ  ? C LYS 368 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0411 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XXD 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     109.560 
_cell.length_a_esd                 ? 
_cell.length_b                     109.560 
_cell.length_b_esd                 ? 
_cell.length_c                     265.200 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        24 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XXD 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                96 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 43 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XXD 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.61 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          52.87 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '2.2M Ammonium sulfate, 0.1 M BIS-TRIS pH 6.5' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-01-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9792 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL10U2' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9792 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL10U2 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8XXD 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.32 
_reflns.d_resolution_low                               50.63 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     70755 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                25.0 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          14.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.190 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.182 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.32 
_reflns_shell.d_res_low                                     2.38 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           3.4 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             5145 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.383 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.854 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.366 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            0.01 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][2]                            0.01 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -0.03 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               52.502 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.960 
_refine.correlation_coeff_Fo_to_Fc_free          0.937 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8XXD 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.32 
_refine.ls_d_res_low                             50.63 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     67128 
_refine.ls_number_reflns_R_free                  3545 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.90 
_refine.ls_percent_reflns_R_free                 5.0 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.19076 
_refine.ls_R_factor_R_free                       0.24278 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.18808 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.308 
_refine.pdbx_overall_ESU_R_Free                  0.232 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             7.321 
_refine.overall_SU_ML                            0.175 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.32 
_refine_hist.d_res_low                        50.63 
_refine_hist.number_atoms_solvent             183 
_refine_hist.number_atoms_total               11017 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        10707 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         127 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  11143 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.016  10420 ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.471  1.656  15124 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.481  1.570  23993 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.809  5.000  1340  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 7.523  5.000  87    ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 16.336 10.000 1851  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.068  0.200  1606  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  12972 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  2598  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 4.845  5.057  5363  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 4.841  5.057  5363  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 6.586  9.082  6702  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 6.586  9.083  6703  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.822  5.648  5780  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.817  5.647  5777  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 8.401  10.131 8423  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 9.713  48.82  12830 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 9.715  48.82  12822 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.320 
_refine_ls_shell.d_res_low                        2.380 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             259 
_refine_ls_shell.number_reflns_R_work             4869 
_refine_ls_shell.percent_reflns_obs               99.98 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.308 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.343 
# 
_struct.entry_id                     8XXD 
_struct.title                        'TtCS-citrate-CoA complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XXD 
_struct_keywords.text            'citrate synthase, citrate cleavage, reversible, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 2 ? 
H N N 4 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CISY_THET7 
_struct_ref.pdbx_db_accession          A0A0S3QTD0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKLKERLAELIPQWRAEVAEIRKKYGNRKTMDCTIGHAYGGMRGLKALVCDTSEVFPDEGVKFRGYTIPELREGPHKLPT
AEGGFEPLPEGLWYLLLTGELPTEEDVKEISAEFTKRMQNVPQYVFDVLRAMPVDTHPMTMFAAGILAMQRESVFAKRYE
EGMRREEHWEAMLEDSLNMLAALPVIAAYIYRRKYKGDTHIAPDPNLDWSANLAHMMGFDDFEVYELFRLYMFLHSDHEG
GNVSAHTNLLVNSAYSDIYRSFSAAMNGLAGPLHGLANQEVLRWIQMLYKKFGGVPTKEQLERFAWDTLNSGQVIPGYGH
AVLRVTDPRYVAQRDFALKHLPDDELFKIVSLCYEVIPEVLKKHGKAKNPWPNVDAHSGVLLWHYGIREYDFYTVLFGVS
RALGCTAQAILVRGYMLPIERPKSITTRWVKEVAESLPVAGS
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XXD A 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
2 1 8XXD B 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
3 1 8XXD C 1 ? 442 ? A0A0S3QTD0 1 ? 442 ? 1 442 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XXD LYS A 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 1  
1 8XXD LEU A 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 2  
1 8XXD ALA A 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 3  
1 8XXD ALA A 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 4  
1 8XXD ALA A 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 5  
1 8XXD LEU A 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 6  
1 8XXD GLU A 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 7  
2 8XXD LYS B 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 8  
2 8XXD LEU B 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 9  
2 8XXD ALA B 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 10 
2 8XXD ALA B 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 11 
2 8XXD ALA B 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 12 
2 8XXD LEU B 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 13 
2 8XXD GLU B 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 14 
3 8XXD LYS C 443 ? UNP A0A0S3QTD0 ? ? 'expression tag' 443 15 
3 8XXD LEU C 444 ? UNP A0A0S3QTD0 ? ? 'expression tag' 444 16 
3 8XXD ALA C 445 ? UNP A0A0S3QTD0 ? ? 'expression tag' 445 17 
3 8XXD ALA C 446 ? UNP A0A0S3QTD0 ? ? 'expression tag' 446 18 
3 8XXD ALA C 447 ? UNP A0A0S3QTD0 ? ? 'expression tag' 447 19 
3 8XXD LEU C 448 ? UNP A0A0S3QTD0 ? ? 'expression tag' 448 20 
3 8XXD GLU C 449 ? UNP A0A0S3QTD0 ? ? 'expression tag' 449 21 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 11620 ? 
1 MORE         -51   ? 
1 'SSA (A^2)'  31070 ? 
2 'ABSA (A^2)' 12500 ? 
2 MORE         -42   ? 
2 'SSA (A^2)'  30050 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1   A,B,D,E,F,I,J 
2 1,2 C,G,H,K       
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z  1.0000000000 0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000 
2 'crystal symmetry operation' 7_555 y,x,-z 0.0000000000 1.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 MET A 1   ? GLY A 26  ? MET A 1   GLY A 26  1 ? 26 
HELX_P HELX_P2  AA2 ILE A 35  ? GLY A 40  ? ILE A 35  GLY A 40  1 ? 6  
HELX_P HELX_P3  AA3 ILE A 68  ? GLU A 73  ? ILE A 68  GLU A 73  1 ? 6  
HELX_P HELX_P4  AA4 LEU A 88  ? GLY A 99  ? LEU A 88  GLY A 99  1 ? 12 
HELX_P HELX_P5  AA5 THR A 103 ? MET A 118 ? THR A 103 MET A 118 1 ? 16 
HELX_P HELX_P6  AA6 PRO A 122 ? MET A 132 ? PRO A 122 MET A 132 1 ? 11 
HELX_P HELX_P7  AA7 HIS A 137 ? MET A 149 ? HIS A 137 MET A 149 1 ? 13 
HELX_P HELX_P8  AA8 GLN A 150 ? GLU A 152 ? GLN A 150 GLU A 152 5 ? 3  
HELX_P HELX_P9  AA9 SER A 153 ? GLY A 162 ? SER A 153 GLY A 162 1 ? 10 
HELX_P HELX_P10 AB1 ARG A 164 ? GLU A 166 ? ARG A 164 GLU A 166 5 ? 3  
HELX_P HELX_P11 AB2 GLU A 167 ? LYS A 196 ? GLU A 167 LYS A 196 1 ? 30 
HELX_P HELX_P12 AB3 ASP A 208 ? GLY A 218 ? ASP A 208 GLY A 218 1 ? 11 
HELX_P HELX_P13 AB4 ASP A 221 ? HIS A 235 ? ASP A 221 HIS A 235 1 ? 15 
HELX_P HELX_P14 AB5 ASN A 242 ? SER A 253 ? ASN A 242 SER A 253 1 ? 12 
HELX_P HELX_P15 AB6 ASP A 257 ? ALA A 270 ? ASP A 257 ALA A 270 1 ? 14 
HELX_P HELX_P16 AB7 GLY A 271 ? LEU A 276 ? GLY A 271 LEU A 276 1 ? 6  
HELX_P HELX_P17 AB8 LEU A 276 ? GLY A 293 ? LEU A 276 GLY A 293 1 ? 18 
HELX_P HELX_P18 AB9 THR A 297 ? ASN A 310 ? THR A 297 ASN A 310 1 ? 14 
HELX_P HELX_P19 AC1 ASP A 327 ? LEU A 341 ? ASP A 327 LEU A 341 1 ? 15 
HELX_P HELX_P20 AC2 ASP A 344 ? GLY A 365 ? ASP A 344 GLY A 365 1 ? 22 
HELX_P HELX_P21 AC3 VAL A 374 ? TYR A 385 ? VAL A 374 TYR A 385 1 ? 12 
HELX_P HELX_P22 AC4 GLU A 389 ? ASP A 391 ? GLU A 389 ASP A 391 5 ? 3  
HELX_P HELX_P23 AC5 PHE A 392 ? MET A 416 ? PHE A 392 MET A 416 1 ? 25 
HELX_P HELX_P24 AC6 THR A 426 ? ALA A 434 ? THR A 426 ALA A 434 1 ? 9  
HELX_P HELX_P25 AC7 SER A 442 ? LEU A 448 ? SER A 442 LEU A 448 1 ? 7  
HELX_P HELX_P26 AC8 LYS B 2   ? TYR B 25  ? LYS B 2   TYR B 25  1 ? 24 
HELX_P HELX_P27 AC9 ILE B 35  ? TYR B 39  ? ILE B 35  TYR B 39  1 ? 5  
HELX_P HELX_P28 AD1 THR B 67  ? GLU B 73  ? THR B 67  GLU B 73  1 ? 7  
HELX_P HELX_P29 AD2 LEU B 88  ? GLY B 99  ? LEU B 88  GLY B 99  1 ? 12 
HELX_P HELX_P30 AD3 THR B 103 ? MET B 118 ? THR B 103 MET B 118 1 ? 16 
HELX_P HELX_P31 AD4 PRO B 122 ? MET B 132 ? PRO B 122 MET B 132 1 ? 11 
HELX_P HELX_P32 AD5 HIS B 137 ? MET B 149 ? HIS B 137 MET B 149 1 ? 13 
HELX_P HELX_P33 AD6 GLN B 150 ? GLU B 152 ? GLN B 150 GLU B 152 5 ? 3  
HELX_P HELX_P34 AD7 SER B 153 ? GLY B 162 ? SER B 153 GLY B 162 1 ? 10 
HELX_P HELX_P35 AD8 ARG B 164 ? GLU B 166 ? ARG B 164 GLU B 166 5 ? 3  
HELX_P HELX_P36 AD9 GLU B 167 ? LYS B 196 ? GLU B 167 LYS B 196 1 ? 30 
HELX_P HELX_P37 AE1 ASP B 208 ? GLY B 218 ? ASP B 208 GLY B 218 1 ? 11 
HELX_P HELX_P38 AE2 ASP B 221 ? HIS B 235 ? ASP B 221 HIS B 235 1 ? 15 
HELX_P HELX_P39 AE3 ASN B 242 ? SER B 253 ? ASN B 242 SER B 253 1 ? 12 
HELX_P HELX_P40 AE4 ASP B 257 ? ALA B 270 ? ASP B 257 ALA B 270 1 ? 14 
HELX_P HELX_P41 AE5 GLY B 271 ? LEU B 276 ? GLY B 271 LEU B 276 1 ? 6  
HELX_P HELX_P42 AE6 LEU B 276 ? PHE B 292 ? LEU B 276 PHE B 292 1 ? 17 
HELX_P HELX_P43 AE7 THR B 297 ? SER B 311 ? THR B 297 SER B 311 1 ? 15 
HELX_P HELX_P44 AE8 ASP B 327 ? LEU B 341 ? ASP B 327 LEU B 341 1 ? 15 
HELX_P HELX_P45 AE9 ASP B 344 ? GLY B 365 ? ASP B 344 GLY B 365 1 ? 22 
HELX_P HELX_P46 AF1 ASN B 373 ? ALA B 376 ? ASN B 373 ALA B 376 5 ? 4  
HELX_P HELX_P47 AF2 HIS B 377 ? TYR B 385 ? HIS B 377 TYR B 385 1 ? 9  
HELX_P HELX_P48 AF3 GLU B 389 ? ASP B 391 ? GLU B 389 ASP B 391 5 ? 3  
HELX_P HELX_P49 AF4 PHE B 392 ? MET B 416 ? PHE B 392 MET B 416 1 ? 25 
HELX_P HELX_P50 AF5 THR B 426 ? ALA B 434 ? THR B 426 ALA B 434 1 ? 9  
HELX_P HELX_P51 AF6 SER B 442 ? LEU B 448 ? SER B 442 LEU B 448 1 ? 7  
HELX_P HELX_P52 AF7 LYS C 2   ? GLY C 26  ? LYS C 2   GLY C 26  1 ? 25 
HELX_P HELX_P53 AF8 THR C 34  ? TYR C 39  ? THR C 34  TYR C 39  1 ? 6  
HELX_P HELX_P54 AF9 ILE C 68  ? GLU C 73  ? ILE C 68  GLU C 73  1 ? 6  
HELX_P HELX_P55 AG1 LEU C 88  ? GLY C 99  ? LEU C 88  GLY C 99  1 ? 12 
HELX_P HELX_P56 AG2 THR C 103 ? MET C 118 ? THR C 103 MET C 118 1 ? 16 
HELX_P HELX_P57 AG3 PRO C 122 ? MET C 132 ? PRO C 122 MET C 132 1 ? 11 
HELX_P HELX_P58 AG4 HIS C 137 ? MET C 149 ? HIS C 137 MET C 149 1 ? 13 
HELX_P HELX_P59 AG5 GLN C 150 ? GLU C 152 ? GLN C 150 GLU C 152 5 ? 3  
HELX_P HELX_P60 AG6 SER C 153 ? GLY C 162 ? SER C 153 GLY C 162 1 ? 10 
HELX_P HELX_P61 AG7 GLU C 167 ? LYS C 196 ? GLU C 167 LYS C 196 1 ? 30 
HELX_P HELX_P62 AG8 ASP C 208 ? GLY C 218 ? ASP C 208 GLY C 218 1 ? 11 
HELX_P HELX_P63 AG9 ASP C 221 ? HIS C 235 ? ASP C 221 HIS C 235 1 ? 15 
HELX_P HELX_P64 AH1 ASN C 242 ? SER C 253 ? ASN C 242 SER C 253 1 ? 12 
HELX_P HELX_P65 AH2 ASP C 257 ? ALA C 270 ? ASP C 257 ALA C 270 1 ? 14 
HELX_P HELX_P66 AH3 GLY C 271 ? LEU C 276 ? GLY C 271 LEU C 276 1 ? 6  
HELX_P HELX_P67 AH4 LEU C 276 ? PHE C 292 ? LEU C 276 PHE C 292 1 ? 17 
HELX_P HELX_P68 AH5 THR C 297 ? SER C 311 ? THR C 297 SER C 311 1 ? 15 
HELX_P HELX_P69 AH6 ASP C 327 ? LEU C 341 ? ASP C 327 LEU C 341 1 ? 15 
HELX_P HELX_P70 AH7 ASP C 344 ? GLY C 365 ? ASP C 344 GLY C 365 1 ? 22 
HELX_P HELX_P71 AH8 ASN C 373 ? ALA C 376 ? ASN C 373 ALA C 376 5 ? 4  
HELX_P HELX_P72 AH9 HIS C 377 ? TYR C 385 ? HIS C 377 TYR C 385 1 ? 9  
HELX_P HELX_P73 AI1 GLU C 389 ? ASP C 391 ? GLU C 389 ASP C 391 5 ? 3  
HELX_P HELX_P74 AI2 PHE C 392 ? MET C 416 ? PHE C 392 MET C 416 1 ? 25 
HELX_P HELX_P75 AI3 THR C 426 ? ALA C 434 ? THR C 426 ALA C 434 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 3 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA4 1 2 ? parallel      
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 29  ? THR A 34  ? LYS A 29  THR A 34  
AA1 2 LYS B 29  ? THR B 34  ? LYS B 29  THR B 34  
AA2 1 LYS A 46  ? VAL A 49  ? LYS A 46  VAL A 49  
AA2 2 LYS B 423 ? ILE B 425 ? LYS B 423 ILE B 425 
AA3 1 SER A 53  ? PHE A 56  ? SER A 53  PHE A 56  
AA3 2 GLY A 60  ? PHE A 63  ? GLY A 60  PHE A 63  
AA3 3 TYR A 66  ? THR A 67  ? TYR A 66  THR A 67  
AA4 1 LYS A 423 ? ILE A 425 ? LYS A 423 ILE A 425 
AA4 2 LYS B 46  ? VAL B 49  ? LYS B 46  VAL B 49  
AA5 1 SER B 53  ? PHE B 56  ? SER B 53  PHE B 56  
AA5 2 GLY B 60  ? PHE B 63  ? GLY B 60  PHE B 63  
AA6 1 SER C 53  ? PHE C 56  ? SER C 53  PHE C 56  
AA6 2 GLY C 60  ? PHE C 63  ? GLY C 60  PHE C 63  
AA6 3 TYR C 66  ? THR C 67  ? TYR C 66  THR C 67  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 30  ? N THR A 30  O CYS B 33  ? O CYS B 33  
AA2 1 2 N LEU A 48  ? N LEU A 48  O ILE B 425 ? O ILE B 425 
AA3 1 2 N PHE A 56  ? N PHE A 56  O GLY A 60  ? O GLY A 60  
AA3 2 3 N PHE A 63  ? N PHE A 63  O TYR A 66  ? O TYR A 66  
AA4 1 2 N ILE A 425 ? N ILE A 425 O LEU B 48  ? O LEU B 48  
AA5 1 2 N PHE B 56  ? N PHE B 56  O GLY B 60  ? O GLY B 60  
AA6 1 2 N PHE C 56  ? N PHE C 56  O GLY C 60  ? O GLY C 60  
AA6 2 3 N PHE C 63  ? N PHE C 63  O TYR C 66  ? O TYR C 66  
# 
_pdbx_entry_details.entry_id                   8XXD 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 57  ? ? -37.14  -34.08  
2  1 GLU A 59  ? ? -173.82 -32.98  
3  1 GLU A 73  ? ? -106.42 -65.09  
4  1 HIS A 76  ? ? -142.81 58.77   
5  1 HIS A 238 ? ? -158.74 59.63   
6  1 GLU A 239 ? ? 69.30   -171.61 
7  1 VAL A 322 ? ? -156.97 -45.39  
8  1 VAL A 325 ? ? -123.89 -159.23 
9  1 LEU A 341 ? ? -149.07 52.58   
10 1 ARG A 421 ? ? -151.47 75.91   
11 1 GLU B 73  ? ? -131.63 -50.32  
12 1 HIS B 238 ? ? -157.85 64.49   
13 1 GLU B 239 ? ? 67.77   -174.87 
14 1 TYR B 255 ? ? 85.06   10.33   
15 1 LEU B 341 ? ? -140.02 51.77   
16 1 CYS C 50  ? ? -164.40 118.75  
17 1 HIS C 238 ? ? -156.56 61.70   
18 1 GLU C 239 ? ? 74.21   -175.95 
19 1 PRO C 272 ? ? -37.56  -39.61  
20 1 VAL C 322 ? ? -132.26 -38.84  
21 1 LEU C 341 ? ? -144.87 55.01   
22 1 MET C 416 ? ? 70.82   47.33   
23 1 ARG C 421 ? ? -150.46 72.42   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   GLU 
_pdbx_validate_peptide_omega.auth_asym_id_1   C 
_pdbx_validate_peptide_omega.auth_seq_id_1    73 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   GLY 
_pdbx_validate_peptide_omega.auth_asym_id_2   C 
_pdbx_validate_peptide_omega.auth_seq_id_2    74 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -135.93 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG A 6   ? ? 0.084 'SIDE CHAIN' 
2 1 ARG A 43  ? ? 0.122 'SIDE CHAIN' 
3 1 ARG A 324 ? ? 0.150 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLU 449 ? A GLU 449 
2 1 Y 1 C LYS 443 ? C LYS 443 
3 1 Y 1 C LEU 444 ? C LEU 444 
4 1 Y 1 C ALA 445 ? C ALA 445 
5 1 Y 1 C ALA 446 ? C ALA 446 
6 1 Y 1 C ALA 447 ? C ALA 447 
7 1 Y 1 C LEU 448 ? C LEU 448 
8 1 Y 1 C GLU 449 ? C GLU 449 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CIT C1   C N N 74  
CIT O1   O N N 75  
CIT O2   O N N 76  
CIT C2   C N N 77  
CIT C3   C N N 78  
CIT O7   O N N 79  
CIT C4   C N N 80  
CIT C5   C N N 81  
CIT O3   O N N 82  
CIT O4   O N N 83  
CIT C6   C N N 84  
CIT O5   O N N 85  
CIT O6   O N N 86  
CIT HO2  H N N 87  
CIT H21  H N N 88  
CIT H22  H N N 89  
CIT HO7  H N N 90  
CIT H41  H N N 91  
CIT H42  H N N 92  
CIT HO4  H N N 93  
CIT HO6  H N N 94  
COA N1A  N Y N 95  
COA C2A  C Y N 96  
COA N3A  N Y N 97  
COA C4A  C Y N 98  
COA C5A  C Y N 99  
COA C6A  C Y N 100 
COA N6A  N N N 101 
COA N7A  N Y N 102 
COA C8A  C Y N 103 
COA N9A  N Y N 104 
COA C1B  C N R 105 
COA C2B  C N R 106 
COA O2B  O N N 107 
COA C3B  C N S 108 
COA O3B  O N N 109 
COA P3B  P N N 110 
COA O7A  O N N 111 
COA O8A  O N N 112 
COA O9A  O N N 113 
COA C4B  C N R 114 
COA O4B  O N N 115 
COA C5B  C N N 116 
COA O5B  O N N 117 
COA P1A  P N S 118 
COA O1A  O N N 119 
COA O2A  O N N 120 
COA O3A  O N N 121 
COA P2A  P N S 122 
COA O4A  O N N 123 
COA O5A  O N N 124 
COA O6A  O N N 125 
COA CBP  C N N 126 
COA CCP  C N N 127 
COA CDP  C N N 128 
COA CEP  C N N 129 
COA CAP  C N R 130 
COA OAP  O N N 131 
COA C9P  C N N 132 
COA O9P  O N N 133 
COA N8P  N N N 134 
COA C7P  C N N 135 
COA C6P  C N N 136 
COA C5P  C N N 137 
COA O5P  O N N 138 
COA N4P  N N N 139 
COA C3P  C N N 140 
COA C2P  C N N 141 
COA S1P  S N N 142 
COA H2A  H N N 143 
COA H61A H N N 144 
COA H62A H N N 145 
COA H8A  H N N 146 
COA H1B  H N N 147 
COA H2B  H N N 148 
COA HO2A H N N 149 
COA H3B  H N N 150 
COA HOA8 H N N 151 
COA HOA9 H N N 152 
COA H4B  H N N 153 
COA H51A H N N 154 
COA H52A H N N 155 
COA HOA2 H N N 156 
COA HOA5 H N N 157 
COA H121 H N N 158 
COA H122 H N N 159 
COA H131 H N N 160 
COA H132 H N N 161 
COA H133 H N N 162 
COA H141 H N N 163 
COA H142 H N N 164 
COA H143 H N N 165 
COA H10  H N N 166 
COA HO1  H N N 167 
COA HN8  H N N 168 
COA H71  H N N 169 
COA H72  H N N 170 
COA H61  H N N 171 
COA H62  H N N 172 
COA HN4  H N N 173 
COA H31  H N N 174 
COA H32  H N N 175 
COA H21  H N N 176 
COA H22  H N N 177 
COA HS1  H N N 178 
CYS N    N N N 179 
CYS CA   C N R 180 
CYS C    C N N 181 
CYS O    O N N 182 
CYS CB   C N N 183 
CYS SG   S N N 184 
CYS OXT  O N N 185 
CYS H    H N N 186 
CYS H2   H N N 187 
CYS HA   H N N 188 
CYS HB2  H N N 189 
CYS HB3  H N N 190 
CYS HG   H N N 191 
CYS HXT  H N N 192 
GLN N    N N N 193 
GLN CA   C N S 194 
GLN C    C N N 195 
GLN O    O N N 196 
GLN CB   C N N 197 
GLN CG   C N N 198 
GLN CD   C N N 199 
GLN OE1  O N N 200 
GLN NE2  N N N 201 
GLN OXT  O N N 202 
GLN H    H N N 203 
GLN H2   H N N 204 
GLN HA   H N N 205 
GLN HB2  H N N 206 
GLN HB3  H N N 207 
GLN HG2  H N N 208 
GLN HG3  H N N 209 
GLN HE21 H N N 210 
GLN HE22 H N N 211 
GLN HXT  H N N 212 
GLU N    N N N 213 
GLU CA   C N S 214 
GLU C    C N N 215 
GLU O    O N N 216 
GLU CB   C N N 217 
GLU CG   C N N 218 
GLU CD   C N N 219 
GLU OE1  O N N 220 
GLU OE2  O N N 221 
GLU OXT  O N N 222 
GLU H    H N N 223 
GLU H2   H N N 224 
GLU HA   H N N 225 
GLU HB2  H N N 226 
GLU HB3  H N N 227 
GLU HG2  H N N 228 
GLU HG3  H N N 229 
GLU HE2  H N N 230 
GLU HXT  H N N 231 
GLY N    N N N 232 
GLY CA   C N N 233 
GLY C    C N N 234 
GLY O    O N N 235 
GLY OXT  O N N 236 
GLY H    H N N 237 
GLY H2   H N N 238 
GLY HA2  H N N 239 
GLY HA3  H N N 240 
GLY HXT  H N N 241 
HIS N    N N N 242 
HIS CA   C N S 243 
HIS C    C N N 244 
HIS O    O N N 245 
HIS CB   C N N 246 
HIS CG   C Y N 247 
HIS ND1  N Y N 248 
HIS CD2  C Y N 249 
HIS CE1  C Y N 250 
HIS NE2  N Y N 251 
HIS OXT  O N N 252 
HIS H    H N N 253 
HIS H2   H N N 254 
HIS HA   H N N 255 
HIS HB2  H N N 256 
HIS HB3  H N N 257 
HIS HD1  H N N 258 
HIS HD2  H N N 259 
HIS HE1  H N N 260 
HIS HE2  H N N 261 
HIS HXT  H N N 262 
HOH O    O N N 263 
HOH H1   H N N 264 
HOH H2   H N N 265 
ILE N    N N N 266 
ILE CA   C N S 267 
ILE C    C N N 268 
ILE O    O N N 269 
ILE CB   C N S 270 
ILE CG1  C N N 271 
ILE CG2  C N N 272 
ILE CD1  C N N 273 
ILE OXT  O N N 274 
ILE H    H N N 275 
ILE H2   H N N 276 
ILE HA   H N N 277 
ILE HB   H N N 278 
ILE HG12 H N N 279 
ILE HG13 H N N 280 
ILE HG21 H N N 281 
ILE HG22 H N N 282 
ILE HG23 H N N 283 
ILE HD11 H N N 284 
ILE HD12 H N N 285 
ILE HD13 H N N 286 
ILE HXT  H N N 287 
LEU N    N N N 288 
LEU CA   C N S 289 
LEU C    C N N 290 
LEU O    O N N 291 
LEU CB   C N N 292 
LEU CG   C N N 293 
LEU CD1  C N N 294 
LEU CD2  C N N 295 
LEU OXT  O N N 296 
LEU H    H N N 297 
LEU H2   H N N 298 
LEU HA   H N N 299 
LEU HB2  H N N 300 
LEU HB3  H N N 301 
LEU HG   H N N 302 
LEU HD11 H N N 303 
LEU HD12 H N N 304 
LEU HD13 H N N 305 
LEU HD21 H N N 306 
LEU HD22 H N N 307 
LEU HD23 H N N 308 
LEU HXT  H N N 309 
LYS N    N N N 310 
LYS CA   C N S 311 
LYS C    C N N 312 
LYS O    O N N 313 
LYS CB   C N N 314 
LYS CG   C N N 315 
LYS CD   C N N 316 
LYS CE   C N N 317 
LYS NZ   N N N 318 
LYS OXT  O N N 319 
LYS H    H N N 320 
LYS H2   H N N 321 
LYS HA   H N N 322 
LYS HB2  H N N 323 
LYS HB3  H N N 324 
LYS HG2  H N N 325 
LYS HG3  H N N 326 
LYS HD2  H N N 327 
LYS HD3  H N N 328 
LYS HE2  H N N 329 
LYS HE3  H N N 330 
LYS HZ1  H N N 331 
LYS HZ2  H N N 332 
LYS HZ3  H N N 333 
LYS HXT  H N N 334 
MET N    N N N 335 
MET CA   C N S 336 
MET C    C N N 337 
MET O    O N N 338 
MET CB   C N N 339 
MET CG   C N N 340 
MET SD   S N N 341 
MET CE   C N N 342 
MET OXT  O N N 343 
MET H    H N N 344 
MET H2   H N N 345 
MET HA   H N N 346 
MET HB2  H N N 347 
MET HB3  H N N 348 
MET HG2  H N N 349 
MET HG3  H N N 350 
MET HE1  H N N 351 
MET HE2  H N N 352 
MET HE3  H N N 353 
MET HXT  H N N 354 
OAA O1   O N N 355 
OAA O2   O N N 356 
OAA O4   O N N 357 
OAA O5   O N N 358 
OAA O3   O N N 359 
OAA C1   C N N 360 
OAA C2   C N N 361 
OAA C3   C N N 362 
OAA C4   C N N 363 
OAA HO5  H N N 364 
OAA H21  H N N 365 
OAA H22  H N N 366 
PHE N    N N N 367 
PHE CA   C N S 368 
PHE C    C N N 369 
PHE O    O N N 370 
PHE CB   C N N 371 
PHE CG   C Y N 372 
PHE CD1  C Y N 373 
PHE CD2  C Y N 374 
PHE CE1  C Y N 375 
PHE CE2  C Y N 376 
PHE CZ   C Y N 377 
PHE OXT  O N N 378 
PHE H    H N N 379 
PHE H2   H N N 380 
PHE HA   H N N 381 
PHE HB2  H N N 382 
PHE HB3  H N N 383 
PHE HD1  H N N 384 
PHE HD2  H N N 385 
PHE HE1  H N N 386 
PHE HE2  H N N 387 
PHE HZ   H N N 388 
PHE HXT  H N N 389 
PRO N    N N N 390 
PRO CA   C N S 391 
PRO C    C N N 392 
PRO O    O N N 393 
PRO CB   C N N 394 
PRO CG   C N N 395 
PRO CD   C N N 396 
PRO OXT  O N N 397 
PRO H    H N N 398 
PRO HA   H N N 399 
PRO HB2  H N N 400 
PRO HB3  H N N 401 
PRO HG2  H N N 402 
PRO HG3  H N N 403 
PRO HD2  H N N 404 
PRO HD3  H N N 405 
PRO HXT  H N N 406 
SER N    N N N 407 
SER CA   C N S 408 
SER C    C N N 409 
SER O    O N N 410 
SER CB   C N N 411 
SER OG   O N N 412 
SER OXT  O N N 413 
SER H    H N N 414 
SER H2   H N N 415 
SER HA   H N N 416 
SER HB2  H N N 417 
SER HB3  H N N 418 
SER HG   H N N 419 
SER HXT  H N N 420 
THR N    N N N 421 
THR CA   C N S 422 
THR C    C N N 423 
THR O    O N N 424 
THR CB   C N R 425 
THR OG1  O N N 426 
THR CG2  C N N 427 
THR OXT  O N N 428 
THR H    H N N 429 
THR H2   H N N 430 
THR HA   H N N 431 
THR HB   H N N 432 
THR HG1  H N N 433 
THR HG21 H N N 434 
THR HG22 H N N 435 
THR HG23 H N N 436 
THR HXT  H N N 437 
TRP N    N N N 438 
TRP CA   C N S 439 
TRP C    C N N 440 
TRP O    O N N 441 
TRP CB   C N N 442 
TRP CG   C Y N 443 
TRP CD1  C Y N 444 
TRP CD2  C Y N 445 
TRP NE1  N Y N 446 
TRP CE2  C Y N 447 
TRP CE3  C Y N 448 
TRP CZ2  C Y N 449 
TRP CZ3  C Y N 450 
TRP CH2  C Y N 451 
TRP OXT  O N N 452 
TRP H    H N N 453 
TRP H2   H N N 454 
TRP HA   H N N 455 
TRP HB2  H N N 456 
TRP HB3  H N N 457 
TRP HD1  H N N 458 
TRP HE1  H N N 459 
TRP HE3  H N N 460 
TRP HZ2  H N N 461 
TRP HZ3  H N N 462 
TRP HH2  H N N 463 
TRP HXT  H N N 464 
TYR N    N N N 465 
TYR CA   C N S 466 
TYR C    C N N 467 
TYR O    O N N 468 
TYR CB   C N N 469 
TYR CG   C Y N 470 
TYR CD1  C Y N 471 
TYR CD2  C Y N 472 
TYR CE1  C Y N 473 
TYR CE2  C Y N 474 
TYR CZ   C Y N 475 
TYR OH   O N N 476 
TYR OXT  O N N 477 
TYR H    H N N 478 
TYR H2   H N N 479 
TYR HA   H N N 480 
TYR HB2  H N N 481 
TYR HB3  H N N 482 
TYR HD1  H N N 483 
TYR HD2  H N N 484 
TYR HE1  H N N 485 
TYR HE2  H N N 486 
TYR HH   H N N 487 
TYR HXT  H N N 488 
VAL N    N N N 489 
VAL CA   C N S 490 
VAL C    C N N 491 
VAL O    O N N 492 
VAL CB   C N N 493 
VAL CG1  C N N 494 
VAL CG2  C N N 495 
VAL OXT  O N N 496 
VAL H    H N N 497 
VAL H2   H N N 498 
VAL HA   H N N 499 
VAL HB   H N N 500 
VAL HG11 H N N 501 
VAL HG12 H N N 502 
VAL HG13 H N N 503 
VAL HG21 H N N 504 
VAL HG22 H N N 505 
VAL HG23 H N N 506 
VAL HXT  H N N 507 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CIT C1  O1   doub N N 70  
CIT C1  O2   sing N N 71  
CIT C1  C2   sing N N 72  
CIT O2  HO2  sing N N 73  
CIT C2  C3   sing N N 74  
CIT C2  H21  sing N N 75  
CIT C2  H22  sing N N 76  
CIT C3  O7   sing N N 77  
CIT C3  C4   sing N N 78  
CIT C3  C6   sing N N 79  
CIT O7  HO7  sing N N 80  
CIT C4  C5   sing N N 81  
CIT C4  H41  sing N N 82  
CIT C4  H42  sing N N 83  
CIT C5  O3   doub N N 84  
CIT C5  O4   sing N N 85  
CIT O4  HO4  sing N N 86  
CIT C6  O5   doub N N 87  
CIT C6  O6   sing N N 88  
CIT O6  HO6  sing N N 89  
COA N1A C2A  sing Y N 90  
COA N1A C6A  doub Y N 91  
COA C2A N3A  doub Y N 92  
COA C2A H2A  sing N N 93  
COA N3A C4A  sing Y N 94  
COA C4A C5A  doub Y N 95  
COA C4A N9A  sing Y N 96  
COA C5A C6A  sing Y N 97  
COA C5A N7A  sing Y N 98  
COA C6A N6A  sing N N 99  
COA N6A H61A sing N N 100 
COA N6A H62A sing N N 101 
COA N7A C8A  doub Y N 102 
COA C8A N9A  sing Y N 103 
COA C8A H8A  sing N N 104 
COA N9A C1B  sing N N 105 
COA C1B C2B  sing N N 106 
COA C1B O4B  sing N N 107 
COA C1B H1B  sing N N 108 
COA C2B O2B  sing N N 109 
COA C2B C3B  sing N N 110 
COA C2B H2B  sing N N 111 
COA O2B HO2A sing N N 112 
COA C3B O3B  sing N N 113 
COA C3B C4B  sing N N 114 
COA C3B H3B  sing N N 115 
COA O3B P3B  sing N N 116 
COA P3B O7A  doub N N 117 
COA P3B O8A  sing N N 118 
COA P3B O9A  sing N N 119 
COA O8A HOA8 sing N N 120 
COA O9A HOA9 sing N N 121 
COA C4B O4B  sing N N 122 
COA C4B C5B  sing N N 123 
COA C4B H4B  sing N N 124 
COA C5B O5B  sing N N 125 
COA C5B H51A sing N N 126 
COA C5B H52A sing N N 127 
COA O5B P1A  sing N N 128 
COA P1A O1A  doub N N 129 
COA P1A O2A  sing N N 130 
COA P1A O3A  sing N N 131 
COA O2A HOA2 sing N N 132 
COA O3A P2A  sing N N 133 
COA P2A O4A  doub N N 134 
COA P2A O5A  sing N N 135 
COA P2A O6A  sing N N 136 
COA O5A HOA5 sing N N 137 
COA O6A CCP  sing N N 138 
COA CBP CCP  sing N N 139 
COA CBP CDP  sing N N 140 
COA CBP CEP  sing N N 141 
COA CBP CAP  sing N N 142 
COA CCP H121 sing N N 143 
COA CCP H122 sing N N 144 
COA CDP H131 sing N N 145 
COA CDP H132 sing N N 146 
COA CDP H133 sing N N 147 
COA CEP H141 sing N N 148 
COA CEP H142 sing N N 149 
COA CEP H143 sing N N 150 
COA CAP OAP  sing N N 151 
COA CAP C9P  sing N N 152 
COA CAP H10  sing N N 153 
COA OAP HO1  sing N N 154 
COA C9P O9P  doub N N 155 
COA C9P N8P  sing N N 156 
COA N8P C7P  sing N N 157 
COA N8P HN8  sing N N 158 
COA C7P C6P  sing N N 159 
COA C7P H71  sing N N 160 
COA C7P H72  sing N N 161 
COA C6P C5P  sing N N 162 
COA C6P H61  sing N N 163 
COA C6P H62  sing N N 164 
COA C5P O5P  doub N N 165 
COA C5P N4P  sing N N 166 
COA N4P C3P  sing N N 167 
COA N4P HN4  sing N N 168 
COA C3P C2P  sing N N 169 
COA C3P H31  sing N N 170 
COA C3P H32  sing N N 171 
COA C2P S1P  sing N N 172 
COA C2P H21  sing N N 173 
COA C2P H22  sing N N 174 
COA S1P HS1  sing N N 175 
CYS N   CA   sing N N 176 
CYS N   H    sing N N 177 
CYS N   H2   sing N N 178 
CYS CA  C    sing N N 179 
CYS CA  CB   sing N N 180 
CYS CA  HA   sing N N 181 
CYS C   O    doub N N 182 
CYS C   OXT  sing N N 183 
CYS CB  SG   sing N N 184 
CYS CB  HB2  sing N N 185 
CYS CB  HB3  sing N N 186 
CYS SG  HG   sing N N 187 
CYS OXT HXT  sing N N 188 
GLN N   CA   sing N N 189 
GLN N   H    sing N N 190 
GLN N   H2   sing N N 191 
GLN CA  C    sing N N 192 
GLN CA  CB   sing N N 193 
GLN CA  HA   sing N N 194 
GLN C   O    doub N N 195 
GLN C   OXT  sing N N 196 
GLN CB  CG   sing N N 197 
GLN CB  HB2  sing N N 198 
GLN CB  HB3  sing N N 199 
GLN CG  CD   sing N N 200 
GLN CG  HG2  sing N N 201 
GLN CG  HG3  sing N N 202 
GLN CD  OE1  doub N N 203 
GLN CD  NE2  sing N N 204 
GLN NE2 HE21 sing N N 205 
GLN NE2 HE22 sing N N 206 
GLN OXT HXT  sing N N 207 
GLU N   CA   sing N N 208 
GLU N   H    sing N N 209 
GLU N   H2   sing N N 210 
GLU CA  C    sing N N 211 
GLU CA  CB   sing N N 212 
GLU CA  HA   sing N N 213 
GLU C   O    doub N N 214 
GLU C   OXT  sing N N 215 
GLU CB  CG   sing N N 216 
GLU CB  HB2  sing N N 217 
GLU CB  HB3  sing N N 218 
GLU CG  CD   sing N N 219 
GLU CG  HG2  sing N N 220 
GLU CG  HG3  sing N N 221 
GLU CD  OE1  doub N N 222 
GLU CD  OE2  sing N N 223 
GLU OE2 HE2  sing N N 224 
GLU OXT HXT  sing N N 225 
GLY N   CA   sing N N 226 
GLY N   H    sing N N 227 
GLY N   H2   sing N N 228 
GLY CA  C    sing N N 229 
GLY CA  HA2  sing N N 230 
GLY CA  HA3  sing N N 231 
GLY C   O    doub N N 232 
GLY C   OXT  sing N N 233 
GLY OXT HXT  sing N N 234 
HIS N   CA   sing N N 235 
HIS N   H    sing N N 236 
HIS N   H2   sing N N 237 
HIS CA  C    sing N N 238 
HIS CA  CB   sing N N 239 
HIS CA  HA   sing N N 240 
HIS C   O    doub N N 241 
HIS C   OXT  sing N N 242 
HIS CB  CG   sing N N 243 
HIS CB  HB2  sing N N 244 
HIS CB  HB3  sing N N 245 
HIS CG  ND1  sing Y N 246 
HIS CG  CD2  doub Y N 247 
HIS ND1 CE1  doub Y N 248 
HIS ND1 HD1  sing N N 249 
HIS CD2 NE2  sing Y N 250 
HIS CD2 HD2  sing N N 251 
HIS CE1 NE2  sing Y N 252 
HIS CE1 HE1  sing N N 253 
HIS NE2 HE2  sing N N 254 
HIS OXT HXT  sing N N 255 
HOH O   H1   sing N N 256 
HOH O   H2   sing N N 257 
ILE N   CA   sing N N 258 
ILE N   H    sing N N 259 
ILE N   H2   sing N N 260 
ILE CA  C    sing N N 261 
ILE CA  CB   sing N N 262 
ILE CA  HA   sing N N 263 
ILE C   O    doub N N 264 
ILE C   OXT  sing N N 265 
ILE CB  CG1  sing N N 266 
ILE CB  CG2  sing N N 267 
ILE CB  HB   sing N N 268 
ILE CG1 CD1  sing N N 269 
ILE CG1 HG12 sing N N 270 
ILE CG1 HG13 sing N N 271 
ILE CG2 HG21 sing N N 272 
ILE CG2 HG22 sing N N 273 
ILE CG2 HG23 sing N N 274 
ILE CD1 HD11 sing N N 275 
ILE CD1 HD12 sing N N 276 
ILE CD1 HD13 sing N N 277 
ILE OXT HXT  sing N N 278 
LEU N   CA   sing N N 279 
LEU N   H    sing N N 280 
LEU N   H2   sing N N 281 
LEU CA  C    sing N N 282 
LEU CA  CB   sing N N 283 
LEU CA  HA   sing N N 284 
LEU C   O    doub N N 285 
LEU C   OXT  sing N N 286 
LEU CB  CG   sing N N 287 
LEU CB  HB2  sing N N 288 
LEU CB  HB3  sing N N 289 
LEU CG  CD1  sing N N 290 
LEU CG  CD2  sing N N 291 
LEU CG  HG   sing N N 292 
LEU CD1 HD11 sing N N 293 
LEU CD1 HD12 sing N N 294 
LEU CD1 HD13 sing N N 295 
LEU CD2 HD21 sing N N 296 
LEU CD2 HD22 sing N N 297 
LEU CD2 HD23 sing N N 298 
LEU OXT HXT  sing N N 299 
LYS N   CA   sing N N 300 
LYS N   H    sing N N 301 
LYS N   H2   sing N N 302 
LYS CA  C    sing N N 303 
LYS CA  CB   sing N N 304 
LYS CA  HA   sing N N 305 
LYS C   O    doub N N 306 
LYS C   OXT  sing N N 307 
LYS CB  CG   sing N N 308 
LYS CB  HB2  sing N N 309 
LYS CB  HB3  sing N N 310 
LYS CG  CD   sing N N 311 
LYS CG  HG2  sing N N 312 
LYS CG  HG3  sing N N 313 
LYS CD  CE   sing N N 314 
LYS CD  HD2  sing N N 315 
LYS CD  HD3  sing N N 316 
LYS CE  NZ   sing N N 317 
LYS CE  HE2  sing N N 318 
LYS CE  HE3  sing N N 319 
LYS NZ  HZ1  sing N N 320 
LYS NZ  HZ2  sing N N 321 
LYS NZ  HZ3  sing N N 322 
LYS OXT HXT  sing N N 323 
MET N   CA   sing N N 324 
MET N   H    sing N N 325 
MET N   H2   sing N N 326 
MET CA  C    sing N N 327 
MET CA  CB   sing N N 328 
MET CA  HA   sing N N 329 
MET C   O    doub N N 330 
MET C   OXT  sing N N 331 
MET CB  CG   sing N N 332 
MET CB  HB2  sing N N 333 
MET CB  HB3  sing N N 334 
MET CG  SD   sing N N 335 
MET CG  HG2  sing N N 336 
MET CG  HG3  sing N N 337 
MET SD  CE   sing N N 338 
MET CE  HE1  sing N N 339 
MET CE  HE2  sing N N 340 
MET CE  HE3  sing N N 341 
MET OXT HXT  sing N N 342 
OAA O1  C1   doub N N 343 
OAA O2  C1   sing N N 344 
OAA O4  C4   doub N N 345 
OAA O5  C4   sing N N 346 
OAA O5  HO5  sing N N 347 
OAA O3  C3   doub N N 348 
OAA C1  C2   sing N N 349 
OAA C2  C3   sing N N 350 
OAA C2  H21  sing N N 351 
OAA C2  H22  sing N N 352 
OAA C3  C4   sing N N 353 
PHE N   CA   sing N N 354 
PHE N   H    sing N N 355 
PHE N   H2   sing N N 356 
PHE CA  C    sing N N 357 
PHE CA  CB   sing N N 358 
PHE CA  HA   sing N N 359 
PHE C   O    doub N N 360 
PHE C   OXT  sing N N 361 
PHE CB  CG   sing N N 362 
PHE CB  HB2  sing N N 363 
PHE CB  HB3  sing N N 364 
PHE CG  CD1  doub Y N 365 
PHE CG  CD2  sing Y N 366 
PHE CD1 CE1  sing Y N 367 
PHE CD1 HD1  sing N N 368 
PHE CD2 CE2  doub Y N 369 
PHE CD2 HD2  sing N N 370 
PHE CE1 CZ   doub Y N 371 
PHE CE1 HE1  sing N N 372 
PHE CE2 CZ   sing Y N 373 
PHE CE2 HE2  sing N N 374 
PHE CZ  HZ   sing N N 375 
PHE OXT HXT  sing N N 376 
PRO N   CA   sing N N 377 
PRO N   CD   sing N N 378 
PRO N   H    sing N N 379 
PRO CA  C    sing N N 380 
PRO CA  CB   sing N N 381 
PRO CA  HA   sing N N 382 
PRO C   O    doub N N 383 
PRO C   OXT  sing N N 384 
PRO CB  CG   sing N N 385 
PRO CB  HB2  sing N N 386 
PRO CB  HB3  sing N N 387 
PRO CG  CD   sing N N 388 
PRO CG  HG2  sing N N 389 
PRO CG  HG3  sing N N 390 
PRO CD  HD2  sing N N 391 
PRO CD  HD3  sing N N 392 
PRO OXT HXT  sing N N 393 
SER N   CA   sing N N 394 
SER N   H    sing N N 395 
SER N   H2   sing N N 396 
SER CA  C    sing N N 397 
SER CA  CB   sing N N 398 
SER CA  HA   sing N N 399 
SER C   O    doub N N 400 
SER C   OXT  sing N N 401 
SER CB  OG   sing N N 402 
SER CB  HB2  sing N N 403 
SER CB  HB3  sing N N 404 
SER OG  HG   sing N N 405 
SER OXT HXT  sing N N 406 
THR N   CA   sing N N 407 
THR N   H    sing N N 408 
THR N   H2   sing N N 409 
THR CA  C    sing N N 410 
THR CA  CB   sing N N 411 
THR CA  HA   sing N N 412 
THR C   O    doub N N 413 
THR C   OXT  sing N N 414 
THR CB  OG1  sing N N 415 
THR CB  CG2  sing N N 416 
THR CB  HB   sing N N 417 
THR OG1 HG1  sing N N 418 
THR CG2 HG21 sing N N 419 
THR CG2 HG22 sing N N 420 
THR CG2 HG23 sing N N 421 
THR OXT HXT  sing N N 422 
TRP N   CA   sing N N 423 
TRP N   H    sing N N 424 
TRP N   H2   sing N N 425 
TRP CA  C    sing N N 426 
TRP CA  CB   sing N N 427 
TRP CA  HA   sing N N 428 
TRP C   O    doub N N 429 
TRP C   OXT  sing N N 430 
TRP CB  CG   sing N N 431 
TRP CB  HB2  sing N N 432 
TRP CB  HB3  sing N N 433 
TRP CG  CD1  doub Y N 434 
TRP CG  CD2  sing Y N 435 
TRP CD1 NE1  sing Y N 436 
TRP CD1 HD1  sing N N 437 
TRP CD2 CE2  doub Y N 438 
TRP CD2 CE3  sing Y N 439 
TRP NE1 CE2  sing Y N 440 
TRP NE1 HE1  sing N N 441 
TRP CE2 CZ2  sing Y N 442 
TRP CE3 CZ3  doub Y N 443 
TRP CE3 HE3  sing N N 444 
TRP CZ2 CH2  doub Y N 445 
TRP CZ2 HZ2  sing N N 446 
TRP CZ3 CH2  sing Y N 447 
TRP CZ3 HZ3  sing N N 448 
TRP CH2 HH2  sing N N 449 
TRP OXT HXT  sing N N 450 
TYR N   CA   sing N N 451 
TYR N   H    sing N N 452 
TYR N   H2   sing N N 453 
TYR CA  C    sing N N 454 
TYR CA  CB   sing N N 455 
TYR CA  HA   sing N N 456 
TYR C   O    doub N N 457 
TYR C   OXT  sing N N 458 
TYR CB  CG   sing N N 459 
TYR CB  HB2  sing N N 460 
TYR CB  HB3  sing N N 461 
TYR CG  CD1  doub Y N 462 
TYR CG  CD2  sing Y N 463 
TYR CD1 CE1  sing Y N 464 
TYR CD1 HD1  sing N N 465 
TYR CD2 CE2  doub Y N 466 
TYR CD2 HD2  sing N N 467 
TYR CE1 CZ   doub Y N 468 
TYR CE1 HE1  sing N N 469 
TYR CE2 CZ   sing Y N 470 
TYR CE2 HE2  sing N N 471 
TYR CZ  OH   sing N N 472 
TYR OH  HH   sing N N 473 
TYR OXT HXT  sing N N 474 
VAL N   CA   sing N N 475 
VAL N   H    sing N N 476 
VAL N   H2   sing N N 477 
VAL CA  C    sing N N 478 
VAL CA  CB   sing N N 479 
VAL CA  HA   sing N N 480 
VAL C   O    doub N N 481 
VAL C   OXT  sing N N 482 
VAL CB  CG1  sing N N 483 
VAL CB  CG2  sing N N 484 
VAL CB  HB   sing N N 485 
VAL CG1 HG11 sing N N 486 
VAL CG1 HG12 sing N N 487 
VAL CG1 HG13 sing N N 488 
VAL CG2 HG21 sing N N 489 
VAL CG2 HG22 sing N N 490 
VAL CG2 HG23 sing N N 491 
VAL OXT HXT  sing N N 492 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   A0A0S3QTD0 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8XXD 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009127 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.009127 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.003771 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . MET A 1 1   ? -36.742 -16.793 -28.798 1.00 75.08  ? 1   MET A N   1 
ATOM   2     C CA  . MET A 1 1   ? -35.584 -16.526 -29.696 1.00 77.07  ? 1   MET A CA  1 
ATOM   3     C C   . MET A 1 1   ? -35.680 -17.458 -30.912 1.00 75.96  ? 1   MET A C   1 
ATOM   4     O O   . MET A 1 1   ? -35.899 -18.663 -30.781 1.00 61.78  ? 1   MET A O   1 
ATOM   5     C CB  . MET A 1 1   ? -34.267 -16.725 -28.927 1.00 76.93  ? 1   MET A CB  1 
ATOM   6     C CG  . MET A 1 1   ? -33.025 -16.841 -29.807 1.00 76.39  ? 1   MET A CG  1 
ATOM   7     S SD  . MET A 1 1   ? -31.464 -16.755 -28.869 1.00 83.67  ? 1   MET A SD  1 
ATOM   8     C CE  . MET A 1 1   ? -31.787 -17.964 -27.583 1.00 91.76  ? 1   MET A CE  1 
ATOM   9     N N   . LYS A 1 2   ? -35.559 -16.882 -32.113 1.00 74.44  ? 2   LYS A N   1 
ATOM   10    C CA  . LYS A 1 2   ? -35.720 -17.641 -33.340 1.00 68.71  ? 2   LYS A CA  1 
ATOM   11    C C   . LYS A 1 2   ? -34.766 -18.840 -33.327 1.00 70.54  ? 2   LYS A C   1 
ATOM   12    O O   . LYS A 1 2   ? -35.159 -19.961 -33.655 1.00 68.93  ? 2   LYS A O   1 
ATOM   13    C CB  . LYS A 1 2   ? -35.498 -16.708 -34.533 1.00 69.93  ? 2   LYS A CB  1 
ATOM   14    C CG  . LYS A 1 2   ? -35.574 -17.363 -35.904 1.00 76.62  ? 2   LYS A CG  1 
ATOM   15    C CD  . LYS A 1 2   ? -36.934 -17.913 -36.220 1.00 85.37  ? 2   LYS A CD  1 
ATOM   16    C CE  . LYS A 1 2   ? -36.984 -18.559 -37.584 1.00 90.54  ? 2   LYS A CE  1 
ATOM   17    N NZ  . LYS A 1 2   ? -38.383 -18.868 -37.942 1.00 100.05 ? 2   LYS A NZ  1 
ATOM   18    N N   . LEU A 1 3   ? -33.509 -18.601 -32.927 1.00 63.90  ? 3   LEU A N   1 
ATOM   19    C CA  . LEU A 1 3   ? -32.481 -19.629 -32.927 1.00 60.63  ? 3   LEU A CA  1 
ATOM   20    C C   . LEU A 1 3   ? -32.993 -20.875 -32.212 1.00 56.06  ? 3   LEU A C   1 
ATOM   21    O O   . LEU A 1 3   ? -32.923 -21.984 -32.736 1.00 54.14  ? 3   LEU A O   1 
ATOM   22    C CB  . LEU A 1 3   ? -31.225 -19.078 -32.246 1.00 60.71  ? 3   LEU A CB  1 
ATOM   23    C CG  . LEU A 1 3   ? -30.111 -20.091 -32.007 1.00 61.97  ? 3   LEU A CG  1 
ATOM   24    C CD1 . LEU A 1 3   ? -29.624 -20.659 -33.333 1.00 55.78  ? 3   LEU A CD1 1 
ATOM   25    C CD2 . LEU A 1 3   ? -28.972 -19.450 -31.232 1.00 68.92  ? 3   LEU A CD2 1 
ATOM   26    N N   . LYS A 1 4   ? -33.534 -20.672 -31.016 1.00 56.13  ? 4   LYS A N   1 
ATOM   27    C CA  . LYS A 1 4   ? -33.920 -21.773 -30.158 1.00 57.54  ? 4   LYS A CA  1 
ATOM   28    C C   . LYS A 1 4   ? -35.160 -22.474 -30.706 1.00 62.15  ? 4   LYS A C   1 
ATOM   29    O O   . LYS A 1 4   ? -35.261 -23.686 -30.564 1.00 72.26  ? 4   LYS A O   1 
ATOM   30    C CB  . LYS A 1 4   ? -34.179 -21.286 -28.732 1.00 53.18  ? 4   LYS A CB  1 
ATOM   31    C CG  . LYS A 1 4   ? -34.408 -22.424 -27.761 1.00 58.31  ? 4   LYS A CG  1 
ATOM   32    C CD  . LYS A 1 4   ? -34.871 -22.003 -26.398 1.00 59.48  ? 4   LYS A CD  1 
ATOM   33    C CE  . LYS A 1 4   ? -35.079 -23.224 -25.539 1.00 62.27  ? 4   LYS A CE  1 
ATOM   34    N NZ  . LYS A 1 4   ? -35.316 -22.829 -24.138 1.00 71.11  ? 4   LYS A NZ  1 
ATOM   35    N N   . GLU A 1 5   ? -36.115 -21.725 -31.279 1.00 63.28  ? 5   GLU A N   1 
ATOM   36    C CA  . GLU A 1 5   ? -37.291 -22.324 -31.905 1.00 66.60  ? 5   GLU A CA  1 
ATOM   37    C C   . GLU A 1 5   ? -36.837 -23.235 -33.042 1.00 61.98  ? 5   GLU A C   1 
ATOM   38    O O   . GLU A 1 5   ? -37.257 -24.382 -33.149 1.00 63.25  ? 5   GLU A O   1 
ATOM   39    C CB  . GLU A 1 5   ? -38.230 -21.281 -32.524 1.00 78.89  ? 5   GLU A CB  1 
ATOM   40    C CG  . GLU A 1 5   ? -38.922 -20.350 -31.535 1.00 87.36  ? 5   GLU A CG  1 
ATOM   41    C CD  . GLU A 1 5   ? -39.614 -19.148 -32.171 1.00 89.36  ? 5   GLU A CD  1 
ATOM   42    O OE1 . GLU A 1 5   ? -39.793 -18.142 -31.458 1.00 79.87  ? 5   GLU A OE1 1 
ATOM   43    O OE2 . GLU A 1 5   ? -39.979 -19.218 -33.379 1.00 85.03  ? 5   GLU A OE2 1 
ATOM   44    N N   . ARG A 1 6   ? -35.952 -22.695 -33.880 1.00 60.86  ? 6   ARG A N   1 
ATOM   45    C CA  . ARG A 1 6   ? -35.400 -23.419 -35.012 1.00 59.13  ? 6   ARG A CA  1 
ATOM   46    C C   . ARG A 1 6   ? -34.699 -24.701 -34.562 1.00 55.08  ? 6   ARG A C   1 
ATOM   47    O O   . ARG A 1 6   ? -34.910 -25.730 -35.188 1.00 57.14  ? 6   ARG A O   1 
ATOM   48    C CB  . ARG A 1 6   ? -34.447 -22.499 -35.769 1.00 65.18  ? 6   ARG A CB  1 
ATOM   49    C CG  . ARG A 1 6   ? -34.352 -22.796 -37.253 1.00 73.24  ? 6   ARG A CG  1 
ATOM   50    C CD  . ARG A 1 6   ? -35.676 -22.590 -37.981 1.00 66.71  ? 6   ARG A CD  1 
ATOM   51    N NE  . ARG A 1 6   ? -35.697 -23.517 -39.097 1.00 63.97  ? 6   ARG A NE  1 
ATOM   52    C CZ  . ARG A 1 6   ? -36.291 -24.697 -39.081 1.00 58.69  ? 6   ARG A CZ  1 
ATOM   53    N NH1 . ARG A 1 6   ? -37.218 -24.958 -38.179 1.00 58.90  ? 6   ARG A NH1 1 
ATOM   54    N NH2 . ARG A 1 6   ? -35.980 -25.593 -39.999 1.00 62.87  ? 6   ARG A NH2 1 
ATOM   55    N N   . LEU A 1 7   ? -33.889 -24.645 -33.484 1.00 54.92  ? 7   LEU A N   1 
ATOM   56    C CA  . LEU A 1 7   ? -33.191 -25.821 -32.959 1.00 52.85  ? 7   LEU A CA  1 
ATOM   57    C C   . LEU A 1 7   ? -34.198 -26.810 -32.365 1.00 44.50  ? 7   LEU A C   1 
ATOM   58    O O   . LEU A 1 7   ? -34.007 -28.018 -32.443 1.00 40.52  ? 7   LEU A O   1 
ATOM   59    C CB  . LEU A 1 7   ? -32.135 -25.417 -31.904 1.00 53.15  ? 7   LEU A CB  1 
ATOM   60    C CG  . LEU A 1 7   ? -30.820 -24.809 -32.425 1.00 46.52  ? 7   LEU A CG  1 
ATOM   61    C CD1 . LEU A 1 7   ? -29.912 -24.414 -31.270 1.00 46.12  ? 7   LEU A CD1 1 
ATOM   62    C CD2 . LEU A 1 7   ? -30.081 -25.758 -33.341 1.00 39.65  ? 7   LEU A CD2 1 
ATOM   63    N N   . ALA A 1 8   ? -35.262 -26.295 -31.740 1.00 48.56  ? 8   ALA A N   1 
ATOM   64    C CA  . ALA A 1 8   ? -36.268 -27.123 -31.091 1.00 53.70  ? 8   ALA A CA  1 
ATOM   65    C C   . ALA A 1 8   ? -36.959 -28.045 -32.107 1.00 56.83  ? 8   ALA A C   1 
ATOM   66    O O   . ALA A 1 8   ? -37.459 -29.109 -31.744 1.00 54.31  ? 8   ALA A O   1 
ATOM   67    C CB  . ALA A 1 8   ? -37.265 -26.241 -30.367 1.00 56.91  ? 8   ALA A CB  1 
ATOM   68    N N   . GLU A 1 9   ? -36.911 -27.677 -33.391 1.00 54.19  ? 9   GLU A N   1 
ATOM   69    C CA  . GLU A 1 9   ? -37.423 -28.524 -34.453 1.00 63.82  ? 9   GLU A CA  1 
ATOM   70    C C   . GLU A 1 9   ? -36.289 -29.330 -35.084 1.00 55.99  ? 9   GLU A C   1 
ATOM   71    O O   . GLU A 1 9   ? -36.454 -30.511 -35.338 1.00 62.85  ? 9   GLU A O   1 
ATOM   72    C CB  . GLU A 1 9   ? -38.130 -27.677 -35.512 1.00 68.43  ? 9   GLU A CB  1 
ATOM   73    C CG  . GLU A 1 9   ? -39.351 -26.946 -34.982 1.00 80.85  ? 9   GLU A CG  1 
ATOM   74    C CD  . GLU A 1 9   ? -40.284 -26.435 -36.074 1.00 104.70 ? 9   GLU A CD  1 
ATOM   75    O OE1 . GLU A 1 9   ? -40.349 -25.175 -36.274 1.00 88.01  ? 9   GLU A OE1 1 
ATOM   76    O OE2 . GLU A 1 9   ? -40.954 -27.297 -36.727 1.00 90.23  ? 9   GLU A OE2 1 
ATOM   77    N N   . LEU A 1 10  ? -35.135 -28.714 -35.340 1.00 49.02  ? 10  LEU A N   1 
ATOM   78    C CA  . LEU A 1 10  ? -34.112 -29.410 -36.102 1.00 53.58  ? 10  LEU A CA  1 
ATOM   79    C C   . LEU A 1 10  ? -33.421 -30.473 -35.254 1.00 53.26  ? 10  LEU A C   1 
ATOM   80    O O   . LEU A 1 10  ? -33.005 -31.482 -35.805 1.00 52.63  ? 10  LEU A O   1 
ATOM   81    C CB  . LEU A 1 10  ? -33.101 -28.423 -36.688 1.00 52.19  ? 10  LEU A CB  1 
ATOM   82    C CG  . LEU A 1 10  ? -33.576 -27.607 -37.895 1.00 53.89  ? 10  LEU A CG  1 
ATOM   83    C CD1 . LEU A 1 10  ? -32.683 -26.393 -38.123 1.00 54.30  ? 10  LEU A CD1 1 
ATOM   84    C CD2 . LEU A 1 10  ? -33.626 -28.454 -39.164 1.00 52.23  ? 10  LEU A CD2 1 
ATOM   85    N N   . ILE A 1 11  ? -33.300 -30.276 -33.933 1.00 50.98  ? 11  ILE A N   1 
ATOM   86    C CA  . ILE A 1 11  ? -32.460 -31.176 -33.143 1.00 52.33  ? 11  ILE A CA  1 
ATOM   87    C C   . ILE A 1 11  ? -33.116 -32.554 -33.011 1.00 49.92  ? 11  ILE A C   1 
ATOM   88    O O   . ILE A 1 11  ? -32.416 -33.553 -33.189 1.00 44.80  ? 11  ILE A O   1 
ATOM   89    C CB  . ILE A 1 11  ? -32.038 -30.589 -31.771 1.00 49.11  ? 11  ILE A CB  1 
ATOM   90    C CG1 . ILE A 1 11  ? -30.806 -29.692 -31.913 1.00 52.28  ? 11  ILE A CG1 1 
ATOM   91    C CG2 . ILE A 1 11  ? -31.775 -31.683 -30.743 1.00 46.66  ? 11  ILE A CG2 1 
ATOM   92    C CD1 . ILE A 1 11  ? -30.405 -28.984 -30.636 1.00 55.78  ? 11  ILE A CD1 1 
ATOM   93    N N   . PRO A 1 12  ? -34.423 -32.681 -32.656 1.00 52.62  ? 12  PRO A N   1 
ATOM   94    C CA  . PRO A 1 12  ? -35.079 -33.997 -32.594 1.00 60.95  ? 12  PRO A CA  1 
ATOM   95    C C   . PRO A 1 12  ? -34.995 -34.796 -33.901 1.00 61.81  ? 12  PRO A C   1 
ATOM   96    O O   . PRO A 1 12  ? -34.879 -36.019 -33.880 1.00 66.54  ? 12  PRO A O   1 
ATOM   97    C CB  . PRO A 1 12  ? -36.544 -33.670 -32.258 1.00 66.33  ? 12  PRO A CB  1 
ATOM   98    C CG  . PRO A 1 12  ? -36.506 -32.283 -31.632 1.00 63.17  ? 12  PRO A CG  1 
ATOM   99    C CD  . PRO A 1 12  ? -35.335 -31.584 -32.294 1.00 62.21  ? 12  PRO A CD  1 
ATOM   100   N N   . GLN A 1 13  ? -34.991 -34.085 -35.034 1.00 55.60  ? 13  GLN A N   1 
ATOM   101   C CA  . GLN A 1 13  ? -34.806 -34.707 -36.334 1.00 62.26  ? 13  GLN A CA  1 
ATOM   102   C C   . GLN A 1 13  ? -33.404 -35.284 -36.463 1.00 57.27  ? 13  GLN A C   1 
ATOM   103   O O   . GLN A 1 13  ? -33.255 -36.469 -36.716 1.00 59.27  ? 13  GLN A O   1 
ATOM   104   C CB  . GLN A 1 13  ? -35.030 -33.698 -37.465 1.00 67.54  ? 13  GLN A CB  1 
ATOM   105   C CG  . GLN A 1 13  ? -36.497 -33.444 -37.784 1.00 73.57  ? 13  GLN A CG  1 
ATOM   106   C CD  . GLN A 1 13  ? -36.638 -32.361 -38.824 1.00 79.96  ? 13  GLN A CD  1 
ATOM   107   O OE1 . GLN A 1 13  ? -36.029 -32.425 -39.893 1.00 74.13  ? 13  GLN A OE1 1 
ATOM   108   N NE2 . GLN A 1 13  ? -37.395 -31.325 -38.491 1.00 82.36  ? 13  GLN A NE2 1 
ATOM   109   N N   . TRP A 1 14  ? -32.384 -34.426 -36.355 1.00 59.14  ? 14  TRP A N   1 
ATOM   110   C CA  . TRP A 1 14  ? -30.993 -34.863 -36.468 1.00 62.45  ? 14  TRP A CA  1 
ATOM   111   C C   . TRP A 1 14  ? -30.684 -35.987 -35.479 1.00 50.39  ? 14  TRP A C   1 
ATOM   112   O O   . TRP A 1 14  ? -29.884 -36.868 -35.773 1.00 56.90  ? 14  TRP A O   1 
ATOM   113   C CB  . TRP A 1 14  ? -30.007 -33.703 -36.249 1.00 61.24  ? 14  TRP A CB  1 
ATOM   114   C CG  . TRP A 1 14  ? -30.042 -32.640 -37.301 1.00 59.22  ? 14  TRP A CG  1 
ATOM   115   C CD1 . TRP A 1 14  ? -30.247 -32.810 -38.640 1.00 56.24  ? 14  TRP A CD1 1 
ATOM   116   C CD2 . TRP A 1 14  ? -29.811 -31.234 -37.099 1.00 59.08  ? 14  TRP A CD2 1 
ATOM   117   N NE1 . TRP A 1 14  ? -30.184 -31.602 -39.275 1.00 59.76  ? 14  TRP A NE1 1 
ATOM   118   C CE2 . TRP A 1 14  ? -29.901 -30.620 -38.363 1.00 52.72  ? 14  TRP A CE2 1 
ATOM   119   C CE3 . TRP A 1 14  ? -29.494 -30.445 -35.984 1.00 59.79  ? 14  TRP A CE3 1 
ATOM   120   C CZ2 . TRP A 1 14  ? -29.722 -29.249 -38.539 1.00 52.75  ? 14  TRP A CZ2 1 
ATOM   121   C CZ3 . TRP A 1 14  ? -29.309 -29.089 -36.161 1.00 58.66  ? 14  TRP A CZ3 1 
ATOM   122   C CH2 . TRP A 1 14  ? -29.443 -28.495 -37.422 1.00 54.55  ? 14  TRP A CH2 1 
ATOM   123   N N   . ARG A 1 15  ? -31.291 -35.929 -34.297 1.00 49.39  ? 15  ARG A N   1 
ATOM   124   C CA  . ARG A 1 15  ? -31.081 -36.951 -33.284 1.00 50.86  ? 15  ARG A CA  1 
ATOM   125   C C   . ARG A 1 15  ? -31.582 -38.294 -33.786 1.00 56.61  ? 15  ARG A C   1 
ATOM   126   O O   . ARG A 1 15  ? -30.882 -39.299 -33.664 1.00 56.36  ? 15  ARG A O   1 
ATOM   127   C CB  . ARG A 1 15  ? -31.836 -36.598 -32.008 1.00 50.76  ? 15  ARG A CB  1 
ATOM   128   C CG  . ARG A 1 15  ? -31.821 -37.695 -30.957 1.00 61.53  ? 15  ARG A CG  1 
ATOM   129   C CD  . ARG A 1 15  ? -32.516 -37.215 -29.702 1.00 70.13  ? 15  ARG A CD  1 
ATOM   130   N NE  . ARG A 1 15  ? -32.831 -38.354 -28.859 1.00 84.57  ? 15  ARG A NE  1 
ATOM   131   C CZ  . ARG A 1 15  ? -34.056 -38.738 -28.515 1.00 95.18  ? 15  ARG A CZ  1 
ATOM   132   N NH1 . ARG A 1 15  ? -35.130 -38.090 -28.950 1.00 90.98  ? 15  ARG A NH1 1 
ATOM   133   N NH2 . ARG A 1 15  ? -34.189 -39.786 -27.723 1.00 92.33  ? 15  ARG A NH2 1 
ATOM   134   N N   . ALA A 1 16  ? -32.821 -38.284 -34.306 1.00 62.68  ? 16  ALA A N   1 
ATOM   135   C CA  . ALA A 1 16  ? -33.424 -39.473 -34.895 1.00 62.46  ? 16  ALA A CA  1 
ATOM   136   C C   . ALA A 1 16  ? -32.571 -39.936 -36.076 1.00 51.26  ? 16  ALA A C   1 
ATOM   137   O O   . ALA A 1 16  ? -32.298 -41.133 -36.215 1.00 48.30  ? 16  ALA A O   1 
ATOM   138   C CB  . ALA A 1 16  ? -34.872 -39.228 -35.287 1.00 58.31  ? 16  ALA A CB  1 
ATOM   139   N N   . GLU A 1 17  ? -32.064 -38.976 -36.856 1.00 48.81  ? 17  GLU A N   1 
ATOM   140   C CA  . GLU A 1 17  ? -31.313 -39.292 -38.065 1.00 57.49  ? 17  GLU A CA  1 
ATOM   141   C C   . GLU A 1 17  ? -29.933 -39.857 -37.734 1.00 62.34  ? 17  GLU A C   1 
ATOM   142   O O   . GLU A 1 17  ? -29.368 -40.617 -38.520 1.00 63.16  ? 17  GLU A O   1 
ATOM   143   C CB  . GLU A 1 17  ? -31.172 -38.041 -38.923 1.00 68.90  ? 17  GLU A CB  1 
ATOM   144   C CG  . GLU A 1 17  ? -30.947 -38.330 -40.396 1.00 86.00  ? 17  GLU A CG  1 
ATOM   145   C CD  . GLU A 1 17  ? -30.701 -37.063 -41.199 1.00 101.04 ? 17  GLU A CD  1 
ATOM   146   O OE1 . GLU A 1 17  ? -29.628 -36.968 -41.837 1.00 101.97 ? 17  GLU A OE1 1 
ATOM   147   O OE2 . GLU A 1 17  ? -31.564 -36.148 -41.142 1.00 96.13  ? 17  GLU A OE2 1 
ATOM   148   N N   . VAL A 1 18  ? -29.368 -39.458 -36.581 1.00 64.45  ? 18  VAL A N   1 
ATOM   149   C CA  . VAL A 1 18  ? -28.081 -39.990 -36.160 1.00 56.58  ? 18  VAL A CA  1 
ATOM   150   C C   . VAL A 1 18  ? -28.282 -41.398 -35.605 1.00 46.78  ? 18  VAL A C   1 
ATOM   151   O O   . VAL A 1 18  ? -27.487 -42.280 -35.895 1.00 44.46  ? 18  VAL A O   1 
ATOM   152   C CB  . VAL A 1 18  ? -27.354 -39.066 -35.160 1.00 54.86  ? 18  VAL A CB  1 
ATOM   153   C CG1 . VAL A 1 18  ? -26.205 -39.777 -34.464 1.00 49.90  ? 18  VAL A CG1 1 
ATOM   154   C CG2 . VAL A 1 18  ? -26.856 -37.789 -35.834 1.00 49.10  ? 18  VAL A CG2 1 
ATOM   155   N N   . ALA A 1 19  ? -29.327 -41.604 -34.799 1.00 46.32  ? 19  ALA A N   1 
ATOM   156   C CA  . ALA A 1 19  ? -29.598 -42.926 -34.240 1.00 56.08  ? 19  ALA A CA  1 
ATOM   157   C C   . ALA A 1 19  ? -29.780 -43.965 -35.356 1.00 56.22  ? 19  ALA A C   1 
ATOM   158   O O   . ALA A 1 19  ? -29.337 -45.104 -35.223 1.00 62.71  ? 19  ALA A O   1 
ATOM   159   C CB  . ALA A 1 19  ? -30.808 -42.869 -33.333 1.00 57.70  ? 19  ALA A CB  1 
ATOM   160   N N   . GLU A 1 20  ? -30.381 -43.532 -36.469 1.00 63.71  ? 20  GLU A N   1 
ATOM   161   C CA  . GLU A 1 20  ? -30.614 -44.355 -37.650 1.00 65.42  ? 20  GLU A CA  1 
ATOM   162   C C   . GLU A 1 20  ? -29.272 -44.703 -38.278 1.00 58.42  ? 20  GLU A C   1 
ATOM   163   O O   . GLU A 1 20  ? -29.003 -45.857 -38.587 1.00 66.49  ? 20  GLU A O   1 
ATOM   164   C CB  . GLU A 1 20  ? -31.576 -43.608 -38.586 1.00 74.27  ? 20  GLU A CB  1 
ATOM   165   C CG  . GLU A 1 20  ? -31.439 -43.928 -40.069 1.00 93.24  ? 20  GLU A CG  1 
ATOM   166   C CD  . GLU A 1 20  ? -32.534 -44.799 -40.658 1.00 97.68  ? 20  GLU A CD  1 
ATOM   167   O OE1 . GLU A 1 20  ? -32.612 -45.981 -40.266 1.00 91.34  ? 20  GLU A OE1 1 
ATOM   168   O OE2 . GLU A 1 20  ? -33.304 -44.284 -41.506 1.00 89.97  ? 20  GLU A OE2 1 
ATOM   169   N N   . ILE A 1 21  ? -28.406 -43.712 -38.466 1.00 60.30  ? 21  ILE A N   1 
ATOM   170   C CA  . ILE A 1 21  ? -27.101 -43.983 -39.051 1.00 59.04  ? 21  ILE A CA  1 
ATOM   171   C C   . ILE A 1 21  ? -26.268 -44.913 -38.170 1.00 55.93  ? 21  ILE A C   1 
ATOM   172   O O   . ILE A 1 21  ? -25.537 -45.722 -38.701 1.00 48.73  ? 21  ILE A O   1 
ATOM   173   C CB  . ILE A 1 21  ? -26.364 -42.674 -39.348 1.00 61.89  ? 21  ILE A CB  1 
ATOM   174   C CG1 . ILE A 1 21  ? -27.100 -41.908 -40.447 1.00 61.37  ? 21  ILE A CG1 1 
ATOM   175   C CG2 . ILE A 1 21  ? -24.899 -42.931 -39.680 1.00 63.71  ? 21  ILE A CG2 1 
ATOM   176   C CD1 . ILE A 1 21  ? -26.813 -40.439 -40.456 1.00 63.60  ? 21  ILE A CD1 1 
ATOM   177   N N   . ARG A 1 22  ? -26.378 -44.842 -36.843 1.00 58.01  ? 22  ARG A N   1 
ATOM   178   C CA  . ARG A 1 22  ? -25.518 -45.668 -36.013 1.00 66.67  ? 22  ARG A CA  1 
ATOM   179   C C   . ARG A 1 22  ? -25.972 -47.125 -36.121 1.00 61.44  ? 22  ARG A C   1 
ATOM   180   O O   . ARG A 1 22  ? -25.141 -48.025 -36.182 1.00 58.88  ? 22  ARG A O   1 
ATOM   181   C CB  . ARG A 1 22  ? -25.496 -45.194 -34.550 1.00 59.78  ? 22  ARG A CB  1 
ATOM   182   C CG  . ARG A 1 22  ? -24.857 -43.825 -34.368 1.00 65.84  ? 22  ARG A CG  1 
ATOM   183   C CD  . ARG A 1 22  ? -24.883 -43.355 -32.921 1.00 61.06  ? 22  ARG A CD  1 
ATOM   184   N NE  . ARG A 1 22  ? -24.098 -44.235 -32.070 1.00 58.52  ? 22  ARG A NE  1 
ATOM   185   C CZ  . ARG A 1 22  ? -24.223 -44.317 -30.746 1.00 54.17  ? 22  ARG A CZ  1 
ATOM   186   N NH1 . ARG A 1 22  ? -25.199 -43.690 -30.116 1.00 58.05  ? 22  ARG A NH1 1 
ATOM   187   N NH2 . ARG A 1 22  ? -23.346 -45.003 -30.043 1.00 52.43  ? 22  ARG A NH2 1 
ATOM   188   N N   . LYS A 1 23  ? -27.291 -47.328 -36.101 1.00 60.17  ? 23  LYS A N   1 
ATOM   189   C CA  . LYS A 1 23  ? -27.912 -48.637 -36.246 1.00 65.30  ? 23  LYS A CA  1 
ATOM   190   C C   . LYS A 1 23  ? -27.599 -49.215 -37.626 1.00 61.38  ? 23  LYS A C   1 
ATOM   191   O O   . LYS A 1 23  ? -26.982 -50.271 -37.728 1.00 63.70  ? 23  LYS A O   1 
ATOM   192   C CB  . LYS A 1 23  ? -29.427 -48.518 -36.035 1.00 64.63  ? 23  LYS A CB  1 
ATOM   193   C CG  . LYS A 1 23  ? -30.096 -49.768 -35.483 1.00 79.49  ? 23  LYS A CG  1 
ATOM   194   C CD  . LYS A 1 23  ? -31.471 -49.494 -34.875 1.00 93.20  ? 23  LYS A CD  1 
ATOM   195   C CE  . LYS A 1 23  ? -31.814 -50.387 -33.694 1.00 96.93  ? 23  LYS A CE  1 
ATOM   196   N NZ  . LYS A 1 23  ? -32.633 -49.659 -32.688 1.00 87.78  ? 23  LYS A NZ  1 
ATOM   197   N N   . LYS A 1 24  ? -27.981 -48.488 -38.682 1.00 55.60  ? 24  LYS A N   1 
ATOM   198   C CA  . LYS A 1 24  ? -27.918 -49.016 -40.032 1.00 60.54  ? 24  LYS A CA  1 
ATOM   199   C C   . LYS A 1 24  ? -26.481 -49.163 -40.528 1.00 58.47  ? 24  LYS A C   1 
ATOM   200   O O   . LYS A 1 24  ? -26.167 -50.168 -41.159 1.00 59.04  ? 24  LYS A O   1 
ATOM   201   C CB  . LYS A 1 24  ? -28.744 -48.128 -40.967 1.00 71.76  ? 24  LYS A CB  1 
ATOM   202   C CG  . LYS A 1 24  ? -28.704 -48.517 -42.438 1.00 81.10  ? 24  LYS A CG  1 
ATOM   203   C CD  . LYS A 1 24  ? -29.544 -47.626 -43.322 1.00 89.25  ? 24  LYS A CD  1 
ATOM   204   C CE  . LYS A 1 24  ? -31.029 -47.858 -43.158 1.00 90.93  ? 24  LYS A CE  1 
ATOM   205   N NZ  . LYS A 1 24  ? -31.772 -47.271 -44.295 1.00 96.61  ? 24  LYS A NZ  1 
ATOM   206   N N   . TYR A 1 25  ? -25.609 -48.175 -40.258 1.00 61.76  ? 25  TYR A N   1 
ATOM   207   C CA  . TYR A 1 25  ? -24.329 -48.062 -40.949 1.00 52.38  ? 25  TYR A CA  1 
ATOM   208   C C   . TYR A 1 25  ? -23.112 -48.165 -40.033 1.00 50.50  ? 25  TYR A C   1 
ATOM   209   O O   . TYR A 1 25  ? -21.972 -48.062 -40.504 1.00 53.38  ? 25  TYR A O   1 
ATOM   210   C CB  . TYR A 1 25  ? -24.248 -46.736 -41.696 1.00 58.71  ? 25  TYR A CB  1 
ATOM   211   C CG  . TYR A 1 25  ? -25.184 -46.609 -42.866 1.00 66.47  ? 25  TYR A CG  1 
ATOM   212   C CD1 . TYR A 1 25  ? -25.258 -47.606 -43.823 1.00 72.24  ? 25  TYR A CD1 1 
ATOM   213   C CD2 . TYR A 1 25  ? -25.957 -45.472 -43.052 1.00 70.89  ? 25  TYR A CD2 1 
ATOM   214   C CE1 . TYR A 1 25  ? -26.093 -47.486 -44.924 1.00 75.31  ? 25  TYR A CE1 1 
ATOM   215   C CE2 . TYR A 1 25  ? -26.798 -45.333 -44.148 1.00 72.77  ? 25  TYR A CE2 1 
ATOM   216   C CZ  . TYR A 1 25  ? -26.866 -46.349 -45.089 1.00 81.44  ? 25  TYR A CZ  1 
ATOM   217   O OH  . TYR A 1 25  ? -27.692 -46.263 -46.188 1.00 85.12  ? 25  TYR A OH  1 
ATOM   218   N N   . GLY A 1 26  ? -23.324 -48.435 -38.745 1.00 56.09  ? 26  GLY A N   1 
ATOM   219   C CA  . GLY A 1 26  ? -22.232 -48.428 -37.778 1.00 55.25  ? 26  GLY A CA  1 
ATOM   220   C C   . GLY A 1 26  ? -21.049 -49.309 -38.171 1.00 52.00  ? 26  GLY A C   1 
ATOM   221   O O   . GLY A 1 26  ? -19.891 -48.978 -37.932 1.00 51.17  ? 26  GLY A O   1 
ATOM   222   N N   . ASN A 1 27  ? -21.349 -50.472 -38.741 1.00 58.99  ? 27  ASN A N   1 
ATOM   223   C CA  . ASN A 1 27  ? -20.335 -51.486 -39.001 1.00 63.45  ? 27  ASN A CA  1 
ATOM   224   C C   . ASN A 1 27  ? -19.646 -51.246 -40.339 1.00 51.91  ? 27  ASN A C   1 
ATOM   225   O O   . ASN A 1 27  ? -18.892 -52.096 -40.787 1.00 54.60  ? 27  ASN A O   1 
ATOM   226   C CB  . ASN A 1 27  ? -20.942 -52.895 -38.997 1.00 71.30  ? 27  ASN A CB  1 
ATOM   227   C CG  . ASN A 1 27  ? -22.185 -52.976 -39.865 1.00 74.60  ? 27  ASN A CG  1 
ATOM   228   O OD1 . ASN A 1 27  ? -22.219 -52.430 -40.970 1.00 69.38  ? 27  ASN A OD1 1 
ATOM   229   N ND2 . ASN A 1 27  ? -23.234 -53.590 -39.345 1.00 68.13  ? 27  ASN A ND2 1 
ATOM   230   N N   . ARG A 1 28  ? -19.941 -50.122 -41.002 1.00 54.39  ? 28  ARG A N   1 
ATOM   231   C CA  . ARG A 1 28  ? -19.255 -49.768 -42.231 1.00 49.30  ? 28  ARG A CA  1 
ATOM   232   C C   . ARG A 1 28  ? -17.857 -49.259 -41.910 1.00 53.09  ? 28  ARG A C   1 
ATOM   233   O O   . ARG A 1 28  ? -17.683 -48.425 -41.023 1.00 51.64  ? 28  ARG A O   1 
ATOM   234   C CB  . ARG A 1 28  ? -20.051 -48.701 -43.000 1.00 61.12  ? 28  ARG A CB  1 
ATOM   235   C CG  . ARG A 1 28  ? -21.405 -49.159 -43.534 1.00 66.00  ? 28  ARG A CG  1 
ATOM   236   C CD  . ARG A 1 28  ? -21.272 -50.303 -44.537 1.00 69.22  ? 28  ARG A CD  1 
ATOM   237   N NE  . ARG A 1 28  ? -22.416 -50.494 -45.434 1.00 75.92  ? 28  ARG A NE  1 
ATOM   238   C CZ  . ARG A 1 28  ? -23.645 -50.811 -45.036 1.00 72.35  ? 28  ARG A CZ  1 
ATOM   239   N NH1 . ARG A 1 28  ? -23.905 -51.043 -43.755 1.00 65.03  ? 28  ARG A NH1 1 
ATOM   240   N NH2 . ARG A 1 28  ? -24.610 -50.900 -45.932 1.00 66.52  ? 28  ARG A NH2 1 
ATOM   241   N N   . LYS A 1 29  ? -16.880 -49.710 -42.696 1.00 51.23  ? 29  LYS A N   1 
ATOM   242   C CA  . LYS A 1 29  ? -15.485 -49.372 -42.495 1.00 50.31  ? 29  LYS A CA  1 
ATOM   243   C C   . LYS A 1 29  ? -15.081 -48.156 -43.317 1.00 57.54  ? 29  LYS A C   1 
ATOM   244   O O   . LYS A 1 29  ? -15.446 -48.057 -44.482 1.00 59.83  ? 29  LYS A O   1 
ATOM   245   C CB  . LYS A 1 29  ? -14.625 -50.565 -42.908 1.00 52.92  ? 29  LYS A CB  1 
ATOM   246   C CG  . LYS A 1 29  ? -13.217 -50.238 -43.346 1.00 49.59  ? 29  LYS A CG  1 
ATOM   247   C CD  . LYS A 1 29  ? -12.378 -51.447 -43.607 1.00 54.45  ? 29  LYS A CD  1 
ATOM   248   C CE  . LYS A 1 29  ? -10.980 -51.066 -44.056 1.00 51.28  ? 29  LYS A CE  1 
ATOM   249   N NZ  . LYS A 1 29  ? -10.055 -52.211 -43.929 1.00 63.40  ? 29  LYS A NZ  1 
ATOM   250   N N   . THR A 1 30  ? -14.247 -47.291 -42.719 1.00 57.24  ? 30  THR A N   1 
ATOM   251   C CA  . THR A 1 30  ? -13.782 -46.062 -43.349 1.00 51.69  ? 30  THR A CA  1 
ATOM   252   C C   . THR A 1 30  ? -12.315 -46.187 -43.728 1.00 47.72  ? 30  THR A C   1 
ATOM   253   O O   . THR A 1 30  ? -11.872 -45.565 -44.689 1.00 47.59  ? 30  THR A O   1 
ATOM   254   C CB  . THR A 1 30  ? -13.947 -44.826 -42.441 1.00 57.12  ? 30  THR A CB  1 
ATOM   255   O OG1 . THR A 1 30  ? -13.319 -45.054 -41.177 1.00 57.15  ? 30  THR A OG1 1 
ATOM   256   C CG2 . THR A 1 30  ? -15.397 -44.458 -42.200 1.00 61.31  ? 30  THR A CG2 1 
ATOM   257   N N   . MET A 1 31  ? -11.541 -46.933 -42.936 1.00 43.07  ? 31  MET A N   1 
ATOM   258   C CA  . MET A 1 31  ? -10.114 -46.944 -43.149 1.00 44.24  ? 31  MET A CA  1 
ATOM   259   C C   . MET A 1 31  ? -9.498  -47.950 -42.185 1.00 47.90  ? 31  MET A C   1 
ATOM   260   O O   . MET A 1 31  ? -10.185 -48.522 -41.328 1.00 43.20  ? 31  MET A O   1 
ATOM   261   C CB  . MET A 1 31  ? -9.480  -45.559 -42.938 1.00 50.09  ? 31  MET A CB  1 
ATOM   262   C CG  . MET A 1 31  ? -9.830  -44.903 -41.561 1.00 56.96  ? 31  MET A CG  1 
ATOM   263   S SD  . MET A 1 31  ? -9.173  -43.206 -41.290 1.00 51.65  ? 31  MET A SD  1 
ATOM   264   C CE  . MET A 1 31  ? -7.470  -43.365 -41.835 1.00 46.47  ? 31  MET A CE  1 
ATOM   265   N N   . ASP A 1 32  ? -8.209  -48.198 -42.416 1.00 46.83  ? 32  ASP A N   1 
ATOM   266   C CA  . ASP A 1 32  ? -7.412  -49.054 -41.567 1.00 53.97  ? 32  ASP A CA  1 
ATOM   267   C C   . ASP A 1 32  ? -6.893  -48.190 -40.415 1.00 58.86  ? 32  ASP A C   1 
ATOM   268   O O   . ASP A 1 32  ? -6.336  -47.120 -40.659 1.00 57.92  ? 32  ASP A O   1 
ATOM   269   C CB  . ASP A 1 32  ? -6.307  -49.711 -42.406 1.00 61.12  ? 32  ASP A CB  1 
ATOM   270   C CG  . ASP A 1 32  ? -6.746  -50.816 -43.373 1.00 64.85  ? 32  ASP A CG  1 
ATOM   271   O OD1 . ASP A 1 32  ? -7.826  -51.392 -43.176 1.00 60.78  ? 32  ASP A OD1 1 
ATOM   272   O OD2 . ASP A 1 32  ? -5.988  -51.111 -44.327 1.00 78.25  ? 32  ASP A OD2 1 
ATOM   273   N N   . CYS A 1 33  ? -7.145  -48.622 -39.165 1.00 61.04  ? 33  CYS A N   1 
ATOM   274   C CA  . CYS A 1 33  ? -6.446  -48.098 -38.004 1.00 52.08  ? 33  CYS A CA  1 
ATOM   275   C C   . CYS A 1 33  ? -5.119  -48.835 -37.896 1.00 48.97  ? 33  CYS A C   1 
ATOM   276   O O   . CYS A 1 33  ? -5.084  -50.055 -37.884 1.00 49.33  ? 33  CYS A O   1 
ATOM   277   C CB  . CYS A 1 33  ? -7.287  -48.262 -36.737 1.00 65.38  ? 33  CYS A CB  1 
ATOM   278   S SG  . CYS A 1 33  ? -6.550  -47.606 -35.208 1.00 57.65  ? 33  CYS A SG  1 
ATOM   279   N N   . THR A 1 34  ? -4.024  -48.088 -37.800 1.00 50.78  ? 34  THR A N   1 
ATOM   280   C CA  . THR A 1 34  ? -2.684  -48.658 -37.782 1.00 48.07  ? 34  THR A CA  1 
ATOM   281   C C   . THR A 1 34  ? -1.950  -48.298 -36.491 1.00 52.93  ? 34  THR A C   1 
ATOM   282   O O   . THR A 1 34  ? -2.407  -47.438 -35.723 1.00 51.97  ? 34  THR A O   1 
ATOM   283   C CB  . THR A 1 34  ? -1.871  -48.140 -38.976 1.00 52.14  ? 34  THR A CB  1 
ATOM   284   O OG1 . THR A 1 34  ? -1.600  -46.748 -38.762 1.00 52.52  ? 34  THR A OG1 1 
ATOM   285   C CG2 . THR A 1 34  ? -2.579  -48.361 -40.303 1.00 51.62  ? 34  THR A CG2 1 
ATOM   286   N N   . ILE A 1 35  ? -0.792  -48.958 -36.296 1.00 48.28  ? 35  ILE A N   1 
ATOM   287   C CA  . ILE A 1 35  ? 0.140   -48.688 -35.214 1.00 48.53  ? 35  ILE A CA  1 
ATOM   288   C C   . ILE A 1 35  ? 0.658   -47.255 -35.291 1.00 54.74  ? 35  ILE A C   1 
ATOM   289   O O   . ILE A 1 35  ? 0.956   -46.643 -34.256 1.00 48.98  ? 35  ILE A O   1 
ATOM   290   C CB  . ILE A 1 35  ? 1.292   -49.701 -35.243 1.00 48.62  ? 35  ILE A CB  1 
ATOM   291   C CG1 . ILE A 1 35  ? 0.799   -51.088 -34.833 1.00 57.07  ? 35  ILE A CG1 1 
ATOM   292   C CG2 . ILE A 1 35  ? 2.446   -49.244 -34.361 1.00 53.04  ? 35  ILE A CG2 1 
ATOM   293   C CD1 . ILE A 1 35  ? 1.883   -52.123 -34.818 1.00 58.09  ? 35  ILE A CD1 1 
ATOM   294   N N   . GLY A 1 36  ? 0.793   -46.772 -36.536 1.00 56.56  ? 36  GLY A N   1 
ATOM   295   C CA  . GLY A 1 36  ? 1.242   -45.425 -36.855 1.00 50.21  ? 36  GLY A CA  1 
ATOM   296   C C   . GLY A 1 36  ? 0.338   -44.365 -36.249 1.00 45.96  ? 36  GLY A C   1 
ATOM   297   O O   . GLY A 1 36  ? 0.858   -43.446 -35.615 1.00 51.03  ? 36  GLY A O   1 
ATOM   298   N N   . HIS A 1 37  ? -0.981  -44.555 -36.432 1.00 41.80  ? 37  HIS A N   1 
ATOM   299   C CA  . HIS A 1 37  ? -2.035  -43.770 -35.803 1.00 44.11  ? 37  HIS A CA  1 
ATOM   300   C C   . HIS A 1 37  ? -1.848  -43.634 -34.285 1.00 48.01  ? 37  HIS A C   1 
ATOM   301   O O   . HIS A 1 37  ? -1.945  -42.534 -33.747 1.00 50.47  ? 37  HIS A O   1 
ATOM   302   C CB  . HIS A 1 37  ? -3.412  -44.344 -36.163 1.00 43.74  ? 37  HIS A CB  1 
ATOM   303   C CG  . HIS A 1 37  ? -3.801  -44.114 -37.590 1.00 53.19  ? 37  HIS A CG  1 
ATOM   304   N ND1 . HIS A 1 37  ? -4.274  -45.092 -38.436 1.00 55.67  ? 37  HIS A ND1 1 
ATOM   305   C CD2 . HIS A 1 37  ? -3.782  -42.986 -38.330 1.00 59.47  ? 37  HIS A CD2 1 
ATOM   306   C CE1 . HIS A 1 37  ? -4.526  -44.572 -39.627 1.00 51.30  ? 37  HIS A CE1 1 
ATOM   307   N NE2 . HIS A 1 37  ? -4.241  -43.292 -39.590 1.00 53.54  ? 37  HIS A NE2 1 
ATOM   308   N N   . ALA A 1 38  ? -1.524  -44.726 -33.589 1.00 48.33  ? 38  ALA A N   1 
ATOM   309   C CA  . ALA A 1 38  ? -1.407  -44.694 -32.131 1.00 54.00  ? 38  ALA A CA  1 
ATOM   310   C C   . ALA A 1 38  ? -0.196  -43.864 -31.674 1.00 49.50  ? 38  ALA A C   1 
ATOM   311   O O   . ALA A 1 38  ? -0.288  -43.101 -30.730 1.00 51.02  ? 38  ALA A O   1 
ATOM   312   C CB  . ALA A 1 38  ? -1.352  -46.105 -31.590 1.00 50.70  ? 38  ALA A CB  1 
ATOM   313   N N   . TYR A 1 39  ? 0.947   -44.041 -32.336 1.00 51.31  ? 39  TYR A N   1 
ATOM   314   C CA  . TYR A 1 39  ? 2.160   -43.295 -32.068 1.00 48.00  ? 39  TYR A CA  1 
ATOM   315   C C   . TYR A 1 39  ? 2.260   -41.966 -32.853 1.00 46.41  ? 39  TYR A C   1 
ATOM   316   O O   . TYR A 1 39  ? 3.256   -41.252 -32.737 1.00 46.36  ? 39  TYR A O   1 
ATOM   317   C CB  . TYR A 1 39  ? 3.357   -44.166 -32.453 1.00 51.66  ? 39  TYR A CB  1 
ATOM   318   C CG  . TYR A 1 39  ? 3.618   -45.330 -31.541 1.00 53.53  ? 39  TYR A CG  1 
ATOM   319   C CD1 . TYR A 1 39  ? 2.973   -46.541 -31.708 1.00 52.86  ? 39  TYR A CD1 1 
ATOM   320   C CD2 . TYR A 1 39  ? 4.498   -45.200 -30.481 1.00 54.07  ? 39  TYR A CD2 1 
ATOM   321   C CE1 . TYR A 1 39  ? 3.205   -47.608 -30.853 1.00 55.20  ? 39  TYR A CE1 1 
ATOM   322   C CE2 . TYR A 1 39  ? 4.721   -46.250 -29.606 1.00 58.78  ? 39  TYR A CE2 1 
ATOM   323   C CZ  . TYR A 1 39  ? 4.072   -47.456 -29.791 1.00 55.08  ? 39  TYR A CZ  1 
ATOM   324   O OH  . TYR A 1 39  ? 4.306   -48.462 -28.904 1.00 56.54  ? 39  TYR A OH  1 
ATOM   325   N N   . GLY A 1 40  ? 1.284   -41.633 -33.702 1.00 40.79  ? 40  GLY A N   1 
ATOM   326   C CA  . GLY A 1 40  ? 1.427   -40.480 -34.573 1.00 42.45  ? 40  GLY A CA  1 
ATOM   327   C C   . GLY A 1 40  ? 0.283   -39.501 -34.414 1.00 44.74  ? 40  GLY A C   1 
ATOM   328   O O   . GLY A 1 40  ? -0.107  -38.862 -35.378 1.00 51.79  ? 40  GLY A O   1 
ATOM   329   N N   . GLY A 1 41  ? -0.275  -39.447 -33.203 1.00 47.58  ? 41  GLY A N   1 
ATOM   330   C CA  . GLY A 1 41  ? -1.267  -38.456 -32.830 1.00 48.33  ? 41  GLY A CA  1 
ATOM   331   C C   . GLY A 1 41  ? -2.570  -38.624 -33.602 1.00 51.09  ? 41  GLY A C   1 
ATOM   332   O O   . GLY A 1 41  ? -3.254  -37.627 -33.844 1.00 44.67  ? 41  GLY A O   1 
ATOM   333   N N   . MET A 1 42  ? -2.876  -39.872 -33.990 1.00 47.53  ? 42  MET A N   1 
ATOM   334   C CA  . MET A 1 42  ? -4.078  -40.214 -34.747 1.00 47.97  ? 42  MET A CA  1 
ATOM   335   C C   . MET A 1 42  ? -4.151  -39.486 -36.099 1.00 40.61  ? 42  MET A C   1 
ATOM   336   O O   . MET A 1 42  ? -5.235  -39.350 -36.632 1.00 47.32  ? 42  MET A O   1 
ATOM   337   C CB  . MET A 1 42  ? -5.353  -39.844 -33.981 1.00 48.79  ? 42  MET A CB  1 
ATOM   338   C CG  . MET A 1 42  ? -5.551  -40.527 -32.649 1.00 56.80  ? 42  MET A CG  1 
ATOM   339   S SD  . MET A 1 42  ? -7.143  -40.034 -31.872 1.00 55.21  ? 42  MET A SD  1 
ATOM   340   C CE  . MET A 1 42  ? -6.909  -40.596 -30.189 1.00 55.45  ? 42  MET A CE  1 
ATOM   341   N N   . ARG A 1 43  ? -3.044  -38.996 -36.661 1.00 41.59  ? 43  ARG A N   1 
ATOM   342   C CA  . ARG A 1 43  ? -3.101  -38.206 -37.886 1.00 49.73  ? 43  ARG A CA  1 
ATOM   343   C C   . ARG A 1 43  ? -3.871  -38.976 -38.957 1.00 52.55  ? 43  ARG A C   1 
ATOM   344   O O   . ARG A 1 43  ? -3.587  -40.131 -39.233 1.00 50.13  ? 43  ARG A O   1 
ATOM   345   C CB  . ARG A 1 43  ? -1.705  -37.884 -38.429 1.00 61.41  ? 43  ARG A CB  1 
ATOM   346   C CG  . ARG A 1 43  ? -1.642  -36.667 -39.351 1.00 77.70  ? 43  ARG A CG  1 
ATOM   347   C CD  . ARG A 1 43  ? -2.017  -35.346 -38.674 1.00 94.42  ? 43  ARG A CD  1 
ATOM   348   N NE  . ARG A 1 43  ? -1.615  -35.342 -37.262 1.00 104.40 ? 43  ARG A NE  1 
ATOM   349   C CZ  . ARG A 1 43  ? -0.557  -34.708 -36.754 1.00 93.92  ? 43  ARG A CZ  1 
ATOM   350   N NH1 . ARG A 1 43  ? -0.087  -33.614 -37.332 1.00 95.23  ? 43  ARG A NH1 1 
ATOM   351   N NH2 . ARG A 1 43  ? -0.011  -35.153 -35.630 1.00 73.25  ? 43  ARG A NH2 1 
ATOM   352   N N   . GLY A 1 44  ? -4.901  -38.342 -39.503 1.00 51.66  ? 44  GLY A N   1 
ATOM   353   C CA  . GLY A 1 44  ? -5.665  -38.913 -40.598 1.00 60.01  ? 44  GLY A CA  1 
ATOM   354   C C   . GLY A 1 44  ? -6.831  -39.793 -40.144 1.00 53.93  ? 44  GLY A C   1 
ATOM   355   O O   . GLY A 1 44  ? -7.704  -40.102 -40.948 1.00 52.11  ? 44  GLY A O   1 
ATOM   356   N N   . LEU A 1 45  ? -6.831  -40.223 -38.875 1.00 51.18  ? 45  LEU A N   1 
ATOM   357   C CA  . LEU A 1 45  ? -7.779  -41.226 -38.423 1.00 46.42  ? 45  LEU A CA  1 
ATOM   358   C C   . LEU A 1 45  ? -9.143  -40.575 -38.232 1.00 51.63  ? 45  LEU A C   1 
ATOM   359   O O   . LEU A 1 45  ? -9.263  -39.573 -37.519 1.00 63.29  ? 45  LEU A O   1 
ATOM   360   C CB  . LEU A 1 45  ? -7.252  -41.859 -37.133 1.00 47.64  ? 45  LEU A CB  1 
ATOM   361   C CG  . LEU A 1 45  ? -7.997  -43.101 -36.642 1.00 55.68  ? 45  LEU A CG  1 
ATOM   362   C CD1 . LEU A 1 45  ? -7.802  -44.274 -37.603 1.00 57.23  ? 45  LEU A CD1 1 
ATOM   363   C CD2 . LEU A 1 45  ? -7.551  -43.491 -35.237 1.00 56.72  ? 45  LEU A CD2 1 
ATOM   364   N N   . LYS A 1 46  ? -10.166 -41.159 -38.872 1.00 52.45  ? 46  LYS A N   1 
ATOM   365   C CA  . LYS A 1 46  ? -11.534 -40.656 -38.825 1.00 53.27  ? 46  LYS A CA  1 
ATOM   366   C C   . LYS A 1 46  ? -12.231 -41.114 -37.549 1.00 50.03  ? 46  LYS A C   1 
ATOM   367   O O   . LYS A 1 46  ? -13.034 -42.041 -37.567 1.00 56.92  ? 46  LYS A O   1 
ATOM   368   C CB  . LYS A 1 46  ? -12.285 -41.107 -40.084 1.00 54.70  ? 46  LYS A CB  1 
ATOM   369   C CG  . LYS A 1 46  ? -11.771 -40.474 -41.372 1.00 59.25  ? 46  LYS A CG  1 
ATOM   370   C CD  . LYS A 1 46  ? -12.370 -41.087 -42.612 1.00 66.10  ? 46  LYS A CD  1 
ATOM   371   C CE  . LYS A 1 46  ? -12.110 -40.285 -43.868 1.00 68.36  ? 46  LYS A CE  1 
ATOM   372   N NZ  . LYS A 1 46  ? -10.689 -40.351 -44.276 1.00 74.43  ? 46  LYS A NZ  1 
ATOM   373   N N   . ALA A 1 47  ? -11.947 -40.436 -36.435 1.00 51.00  ? 47  ALA A N   1 
ATOM   374   C CA  . ALA A 1 47  ? -12.391 -40.928 -35.137 1.00 50.30  ? 47  ALA A CA  1 
ATOM   375   C C   . ALA A 1 47  ? -13.517 -40.087 -34.531 1.00 48.29  ? 47  ALA A C   1 
ATOM   376   O O   . ALA A 1 47  ? -14.082 -40.479 -33.515 1.00 52.54  ? 47  ALA A O   1 
ATOM   377   C CB  . ALA A 1 47  ? -11.208 -41.002 -34.211 1.00 48.12  ? 47  ALA A CB  1 
ATOM   378   N N   . LEU A 1 48  ? -13.880 -38.973 -35.173 1.00 44.58  ? 48  LEU A N   1 
ATOM   379   C CA  . LEU A 1 48  ? -14.699 -37.936 -34.564 1.00 50.33  ? 48  LEU A CA  1 
ATOM   380   C C   . LEU A 1 48  ? -15.784 -37.513 -35.543 1.00 46.00  ? 48  LEU A C   1 
ATOM   381   O O   . LEU A 1 48  ? -15.581 -37.614 -36.748 1.00 48.68  ? 48  LEU A O   1 
ATOM   382   C CB  . LEU A 1 48  ? -13.816 -36.712 -34.267 1.00 54.97  ? 48  LEU A CB  1 
ATOM   383   C CG  . LEU A 1 48  ? -13.118 -36.674 -32.919 1.00 60.03  ? 48  LEU A CG  1 
ATOM   384   C CD1 . LEU A 1 48  ? -12.498 -35.311 -32.679 1.00 59.50  ? 48  LEU A CD1 1 
ATOM   385   C CD2 . LEU A 1 48  ? -14.103 -36.997 -31.811 1.00 73.58  ? 48  LEU A CD2 1 
ATOM   386   N N   . VAL A 1 49  ? -16.888 -36.980 -34.999 1.00 46.06  ? 49  VAL A N   1 
ATOM   387   C CA  . VAL A 1 49  ? -17.952 -36.335 -35.760 1.00 49.86  ? 49  VAL A CA  1 
ATOM   388   C C   . VAL A 1 49  ? -17.963 -34.827 -35.474 1.00 52.44  ? 49  VAL A C   1 
ATOM   389   O O   . VAL A 1 49  ? -18.005 -34.413 -34.314 1.00 51.69  ? 49  VAL A O   1 
ATOM   390   C CB  . VAL A 1 49  ? -19.311 -36.966 -35.394 1.00 48.52  ? 49  VAL A CB  1 
ATOM   391   C CG1 . VAL A 1 49  ? -20.487 -36.211 -35.968 1.00 47.10  ? 49  VAL A CG1 1 
ATOM   392   C CG2 . VAL A 1 49  ? -19.384 -38.424 -35.826 1.00 62.43  ? 49  VAL A CG2 1 
ATOM   393   N N   . CYS A 1 50  ? -17.989 -34.020 -36.545 1.00 53.83  ? 50  CYS A N   1 
ATOM   394   C CA  . CYS A 1 50  ? -18.274 -32.591 -36.477 1.00 48.22  ? 50  CYS A CA  1 
ATOM   395   C C   . CYS A 1 50  ? -19.049 -32.141 -37.723 1.00 45.66  ? 50  CYS A C   1 
ATOM   396   O O   . CYS A 1 50  ? -18.580 -32.351 -38.835 1.00 38.46  ? 50  CYS A O   1 
ATOM   397   C CB  . CYS A 1 50  ? -16.995 -31.779 -36.360 1.00 53.69  ? 50  CYS A CB  1 
ATOM   398   S SG  . CYS A 1 50  ? -17.242 -29.981 -36.405 1.00 53.39  ? 50  CYS A SG  1 
ATOM   399   N N   . ASP A 1 51  ? -20.210 -31.501 -37.497 1.00 39.96  ? 51  ASP A N   1 
ATOM   400   C CA  . ASP A 1 51  ? -21.112 -31.041 -38.538 1.00 46.46  ? 51  ASP A CA  1 
ATOM   401   C C   . ASP A 1 51  ? -21.066 -29.524 -38.705 1.00 44.03  ? 51  ASP A C   1 
ATOM   402   O O   . ASP A 1 51  ? -21.620 -29.000 -39.653 1.00 48.63  ? 51  ASP A O   1 
ATOM   403   C CB  . ASP A 1 51  ? -22.556 -31.454 -38.238 1.00 45.53  ? 51  ASP A CB  1 
ATOM   404   C CG  . ASP A 1 51  ? -22.798 -32.926 -38.507 1.00 51.57  ? 51  ASP A CG  1 
ATOM   405   O OD1 . ASP A 1 51  ? -22.209 -33.410 -39.487 1.00 51.65  ? 51  ASP A OD1 1 
ATOM   406   O OD2 . ASP A 1 51  ? -23.530 -33.583 -37.714 1.00 54.86  ? 51  ASP A OD2 1 
ATOM   407   N N   . THR A 1 52  ? -20.412 -28.802 -37.798 1.00 42.52  ? 52  THR A N   1 
ATOM   408   C CA  . THR A 1 52  ? -20.351 -27.352 -37.904 1.00 38.95  ? 52  THR A CA  1 
ATOM   409   C C   . THR A 1 52  ? -19.489 -26.935 -39.102 1.00 42.64  ? 52  THR A C   1 
ATOM   410   O O   . THR A 1 52  ? -19.774 -25.967 -39.797 1.00 48.83  ? 52  THR A O   1 
ATOM   411   C CB  . THR A 1 52  ? -19.888 -26.766 -36.574 1.00 40.55  ? 52  THR A CB  1 
ATOM   412   O OG1 . THR A 1 52  ? -18.583 -27.256 -36.292 1.00 46.87  ? 52  THR A OG1 1 
ATOM   413   C CG2 . THR A 1 52  ? -20.795 -27.141 -35.421 1.00 44.41  ? 52  THR A CG2 1 
ATOM   414   N N   . SER A 1 53  ? -18.432 -27.681 -39.386 1.00 43.94  ? 53  SER A N   1 
ATOM   415   C CA  . SER A 1 53  ? -17.515 -27.272 -40.429 1.00 41.84  ? 53  SER A CA  1 
ATOM   416   C C   . SER A 1 53  ? -16.718 -28.490 -40.859 1.00 44.26  ? 53  SER A C   1 
ATOM   417   O O   . SER A 1 53  ? -16.760 -29.540 -40.198 1.00 38.05  ? 53  SER A O   1 
ATOM   418   C CB  . SER A 1 53  ? -16.612 -26.163 -39.942 1.00 46.46  ? 53  SER A CB  1 
ATOM   419   O OG  . SER A 1 53  ? -15.815 -26.605 -38.856 1.00 39.34  ? 53  SER A OG  1 
ATOM   420   N N   . GLU A 1 54  ? -15.993 -28.306 -41.963 1.00 48.68  ? 54  GLU A N   1 
ATOM   421   C CA  . GLU A 1 54  ? -15.285 -29.372 -42.657 1.00 51.56  ? 54  GLU A CA  1 
ATOM   422   C C   . GLU A 1 54  ? -14.147 -28.751 -43.474 1.00 51.74  ? 54  GLU A C   1 
ATOM   423   O O   . GLU A 1 54  ? -14.346 -27.801 -44.228 1.00 50.35  ? 54  GLU A O   1 
ATOM   424   C CB  . GLU A 1 54  ? -16.263 -30.166 -43.534 1.00 52.85  ? 54  GLU A CB  1 
ATOM   425   C CG  . GLU A 1 54  ? -15.653 -31.426 -44.168 1.00 64.56  ? 54  GLU A CG  1 
ATOM   426   C CD  . GLU A 1 54  ? -16.515 -32.274 -45.109 1.00 66.00  ? 54  GLU A CD  1 
ATOM   427   O OE1 . GLU A 1 54  ? -16.034 -33.361 -45.547 1.00 68.57  ? 54  GLU A OE1 1 
ATOM   428   O OE2 . GLU A 1 54  ? -17.662 -31.867 -45.396 1.00 60.15  ? 54  GLU A OE2 1 
ATOM   429   N N   . VAL A 1 55  ? -12.938 -29.280 -43.301 1.00 60.36  ? 55  VAL A N   1 
ATOM   430   C CA  . VAL A 1 55  ? -11.775 -28.817 -44.038 1.00 64.17  ? 55  VAL A CA  1 
ATOM   431   C C   . VAL A 1 55  ? -11.596 -29.708 -45.265 1.00 71.06  ? 55  VAL A C   1 
ATOM   432   O O   . VAL A 1 55  ? -11.290 -30.885 -45.101 1.00 77.55  ? 55  VAL A O   1 
ATOM   433   C CB  . VAL A 1 55  ? -10.525 -28.862 -43.143 1.00 71.13  ? 55  VAL A CB  1 
ATOM   434   C CG1 . VAL A 1 55  ? -9.285  -28.422 -43.903 1.00 82.14  ? 55  VAL A CG1 1 
ATOM   435   C CG2 . VAL A 1 55  ? -10.705 -28.044 -41.873 1.00 77.27  ? 55  VAL A CG2 1 
ATOM   436   N N   . PHE A 1 56  ? -11.822 -29.137 -46.464 1.00 73.57  ? 56  PHE A N   1 
ATOM   437   C CA  . PHE A 1 56  ? -11.590 -29.782 -47.754 1.00 74.64  ? 56  PHE A CA  1 
ATOM   438   C C   . PHE A 1 56  ? -10.181 -29.473 -48.272 1.00 86.25  ? 56  PHE A C   1 
ATOM   439   O O   . PHE A 1 56  ? -9.986  -28.395 -48.826 1.00 74.92  ? 56  PHE A O   1 
ATOM   440   C CB  . PHE A 1 56  ? -12.570 -29.267 -48.818 1.00 67.40  ? 56  PHE A CB  1 
ATOM   441   C CG  . PHE A 1 56  ? -14.030 -29.550 -48.565 1.00 71.62  ? 56  PHE A CG  1 
ATOM   442   C CD1 . PHE A 1 56  ? -14.778 -28.725 -47.738 1.00 70.37  ? 56  PHE A CD1 1 
ATOM   443   C CD2 . PHE A 1 56  ? -14.654 -30.649 -49.136 1.00 69.70  ? 56  PHE A CD2 1 
ATOM   444   C CE1 . PHE A 1 56  ? -16.118 -28.985 -47.497 1.00 71.39  ? 56  PHE A CE1 1 
ATOM   445   C CE2 . PHE A 1 56  ? -15.991 -30.913 -48.883 1.00 75.05  ? 56  PHE A CE2 1 
ATOM   446   C CZ  . PHE A 1 56  ? -16.719 -30.082 -48.065 1.00 76.41  ? 56  PHE A CZ  1 
ATOM   447   N N   . PRO A 1 57  ? -9.154  -30.353 -48.140 1.00 103.43 ? 57  PRO A N   1 
ATOM   448   C CA  . PRO A 1 57  ? -7.773  -30.028 -48.541 1.00 100.93 ? 57  PRO A CA  1 
ATOM   449   C C   . PRO A 1 57  ? -7.565  -29.176 -49.798 1.00 89.60  ? 57  PRO A C   1 
ATOM   450   O O   . PRO A 1 57  ? -6.629  -28.416 -49.828 1.00 77.05  ? 57  PRO A O   1 
ATOM   451   C CB  . PRO A 1 57  ? -7.216  -31.417 -48.859 1.00 108.77 ? 57  PRO A CB  1 
ATOM   452   C CG  . PRO A 1 57  ? -7.781  -32.261 -47.753 1.00 109.31 ? 57  PRO A CG  1 
ATOM   453   C CD  . PRO A 1 57  ? -9.184  -31.721 -47.573 1.00 110.98 ? 57  PRO A CD  1 
ATOM   454   N N   . ASP A 1 58  ? -8.424  -29.334 -50.798 1.00 90.55  ? 58  ASP A N   1 
ATOM   455   C CA  . ASP A 1 58  ? -8.254  -28.589 -52.040 1.00 99.79  ? 58  ASP A CA  1 
ATOM   456   C C   . ASP A 1 58  ? -9.373  -27.550 -52.176 1.00 96.34  ? 58  ASP A C   1 
ATOM   457   O O   . ASP A 1 58  ? -10.007 -27.447 -53.224 1.00 95.45  ? 58  ASP A O   1 
ATOM   458   C CB  . ASP A 1 58  ? -8.180  -29.549 -53.238 1.00 118.78 ? 58  ASP A CB  1 
ATOM   459   C CG  . ASP A 1 58  ? -7.116  -30.645 -53.138 1.00 128.46 ? 58  ASP A CG  1 
ATOM   460   O OD1 . ASP A 1 58  ? -5.905  -30.308 -53.099 1.00 131.37 ? 58  ASP A OD1 1 
ATOM   461   O OD2 . ASP A 1 58  ? -7.495  -31.840 -53.116 1.00 113.86 ? 58  ASP A OD2 1 
ATOM   462   N N   . GLU A 1 59  ? -9.618  -26.826 -51.073 1.00 93.44  ? 59  GLU A N   1 
ATOM   463   C CA  . GLU A 1 59  ? -10.684 -25.791 -51.021 1.00 94.39  ? 59  GLU A CA  1 
ATOM   464   C C   . GLU A 1 59  ? -10.595 -25.051 -49.679 1.00 79.18  ? 59  GLU A C   1 
ATOM   465   O O   . GLU A 1 59  ? -10.913 -23.854 -49.658 1.00 67.19  ? 59  GLU A O   1 
ATOM   466   C CB  . GLU A 1 59  ? -12.055 -26.451 -51.153 1.00 98.03  ? 59  GLU A CB  1 
ATOM   467   C CG  . GLU A 1 59  ? -12.868 -25.956 -52.331 1.00 97.07  ? 59  GLU A CG  1 
ATOM   468   C CD  . GLU A 1 59  ? -14.044 -26.854 -52.671 1.00 95.25  ? 59  GLU A CD  1 
ATOM   469   O OE1 . GLU A 1 59  ? -15.123 -26.318 -52.979 1.00 82.48  ? 59  GLU A OE1 1 
ATOM   470   O OE2 . GLU A 1 59  ? -13.877 -28.086 -52.619 1.00 85.14  ? 59  GLU A OE2 1 
ATOM   471   N N   . GLY A 1 60  ? -10.192 -25.731 -48.604 1.00 73.82  ? 60  GLY A N   1 
ATOM   472   C CA  . GLY A 1 60  ? -10.086 -25.157 -47.265 1.00 71.76  ? 60  GLY A CA  1 
ATOM   473   C C   . GLY A 1 60  ? -11.385 -25.305 -46.472 1.00 65.96  ? 60  GLY A C   1 
ATOM   474   O O   . GLY A 1 60  ? -12.270 -26.067 -46.869 1.00 57.18  ? 60  GLY A O   1 
ATOM   475   N N   . VAL A 1 61  ? -11.517 -24.534 -45.381 1.00 60.54  ? 61  VAL A N   1 
ATOM   476   C CA  . VAL A 1 61  ? -12.620 -24.718 -44.451 1.00 47.70  ? 61  VAL A CA  1 
ATOM   477   C C   . VAL A 1 61  ? -13.920 -24.264 -45.111 1.00 44.95  ? 61  VAL A C   1 
ATOM   478   O O   . VAL A 1 61  ? -13.948 -23.238 -45.789 1.00 45.96  ? 61  VAL A O   1 
ATOM   479   C CB  . VAL A 1 61  ? -12.399 -23.998 -43.098 1.00 54.97  ? 61  VAL A CB  1 
ATOM   480   C CG1 . VAL A 1 61  ? -12.411 -22.475 -43.227 1.00 50.29  ? 61  VAL A CG1 1 
ATOM   481   C CG2 . VAL A 1 61  ? -13.413 -24.442 -42.042 1.00 50.22  ? 61  VAL A CG2 1 
ATOM   482   N N   . LYS A 1 62  ? -14.995 -25.036 -44.863 1.00 47.08  ? 62  LYS A N   1 
ATOM   483   C CA  . LYS A 1 62  ? -16.357 -24.622 -45.144 1.00 49.78  ? 62  LYS A CA  1 
ATOM   484   C C   . LYS A 1 62  ? -17.205 -24.734 -43.873 1.00 50.39  ? 62  LYS A C   1 
ATOM   485   O O   . LYS A 1 62  ? -17.157 -25.729 -43.142 1.00 41.86  ? 62  LYS A O   1 
ATOM   486   C CB  . LYS A 1 62  ? -16.983 -25.499 -46.237 1.00 55.61  ? 62  LYS A CB  1 
ATOM   487   C CG  . LYS A 1 62  ? -16.346 -25.425 -47.620 1.00 63.50  ? 62  LYS A CG  1 
ATOM   488   C CD  . LYS A 1 62  ? -17.249 -26.025 -48.705 1.00 74.93  ? 62  LYS A CD  1 
ATOM   489   C CE  . LYS A 1 62  ? -16.545 -26.335 -50.012 1.00 73.38  ? 62  LYS A CE  1 
ATOM   490   N NZ  . LYS A 1 62  ? -17.519 -26.684 -51.069 1.00 72.30  ? 62  LYS A NZ  1 
ATOM   491   N N   . PHE A 1 63  ? -18.063 -23.731 -43.689 1.00 42.26  ? 63  PHE A N   1 
ATOM   492   C CA  . PHE A 1 63  ? -18.913 -23.630 -42.527 1.00 43.47  ? 63  PHE A CA  1 
ATOM   493   C C   . PHE A 1 63  ? -20.326 -24.039 -42.929 1.00 44.38  ? 63  PHE A C   1 
ATOM   494   O O   . PHE A 1 63  ? -21.004 -23.267 -43.606 1.00 41.44  ? 63  PHE A O   1 
ATOM   495   C CB  . PHE A 1 63  ? -18.902 -22.191 -41.995 1.00 46.09  ? 63  PHE A CB  1 
ATOM   496   C CG  . PHE A 1 63  ? -17.581 -21.640 -41.518 1.00 44.89  ? 63  PHE A CG  1 
ATOM   497   C CD1 . PHE A 1 63  ? -16.807 -22.334 -40.598 1.00 48.75  ? 63  PHE A CD1 1 
ATOM   498   C CD2 . PHE A 1 63  ? -17.188 -20.359 -41.849 1.00 45.72  ? 63  PHE A CD2 1 
ATOM   499   C CE1 . PHE A 1 63  ? -15.616 -21.807 -40.114 1.00 42.84  ? 63  PHE A CE1 1 
ATOM   500   C CE2 . PHE A 1 63  ? -16.003 -19.820 -41.356 1.00 45.51  ? 63  PHE A CE2 1 
ATOM   501   C CZ  . PHE A 1 63  ? -15.208 -20.555 -40.512 1.00 45.54  ? 63  PHE A CZ  1 
ATOM   502   N N   . ARG A 1 64  ? -20.771 -25.233 -42.496 1.00 44.76  ? 64  ARG A N   1 
ATOM   503   C CA  . ARG A 1 64  ? -22.027 -25.817 -42.943 1.00 43.93  ? 64  ARG A CA  1 
ATOM   504   C C   . ARG A 1 64  ? -22.161 -25.744 -44.475 1.00 41.86  ? 64  ARG A C   1 
ATOM   505   O O   . ARG A 1 64  ? -23.179 -25.314 -44.989 1.00 49.64  ? 64  ARG A O   1 
ATOM   506   C CB  . ARG A 1 64  ? -23.162 -25.053 -42.256 1.00 44.97  ? 64  ARG A CB  1 
ATOM   507   C CG  . ARG A 1 64  ? -23.335 -25.330 -40.771 1.00 46.00  ? 64  ARG A CG  1 
ATOM   508   C CD  . ARG A 1 64  ? -23.970 -26.688 -40.508 1.00 47.19  ? 64  ARG A CD  1 
ATOM   509   N NE  . ARG A 1 64  ? -24.448 -26.831 -39.136 1.00 50.05  ? 64  ARG A NE  1 
ATOM   510   C CZ  . ARG A 1 64  ? -25.070 -27.903 -38.645 1.00 45.85  ? 64  ARG A CZ  1 
ATOM   511   N NH1 . ARG A 1 64  ? -25.298 -28.960 -39.409 1.00 41.40  ? 64  ARG A NH1 1 
ATOM   512   N NH2 . ARG A 1 64  ? -25.421 -27.928 -37.372 1.00 44.02  ? 64  ARG A NH2 1 
ATOM   513   N N   . GLY A 1 65  ? -21.114 -26.083 -45.223 1.00 48.39  ? 65  GLY A N   1 
ATOM   514   C CA  . GLY A 1 65  ? -21.198 -26.229 -46.676 1.00 47.28  ? 65  GLY A CA  1 
ATOM   515   C C   . GLY A 1 65  ? -20.917 -24.924 -47.418 1.00 48.83  ? 65  GLY A C   1 
ATOM   516   O O   . GLY A 1 65  ? -20.811 -24.886 -48.645 1.00 45.81  ? 65  GLY A O   1 
ATOM   517   N N   . TYR A 1 66  ? -20.786 -23.839 -46.649 1.00 49.88  ? 66  TYR A N   1 
ATOM   518   C CA  . TYR A 1 66  ? -20.593 -22.524 -47.221 1.00 43.79  ? 66  TYR A CA  1 
ATOM   519   C C   . TYR A 1 66  ? -19.137 -22.100 -47.085 1.00 48.23  ? 66  TYR A C   1 
ATOM   520   O O   . TYR A 1 66  ? -18.537 -22.266 -46.034 1.00 54.17  ? 66  TYR A O   1 
ATOM   521   C CB  . TYR A 1 66  ? -21.507 -21.536 -46.531 1.00 45.21  ? 66  TYR A CB  1 
ATOM   522   C CG  . TYR A 1 66  ? -22.985 -21.700 -46.780 1.00 51.68  ? 66  TYR A CG  1 
ATOM   523   C CD1 . TYR A 1 66  ? -23.575 -21.267 -47.963 1.00 52.33  ? 66  TYR A CD1 1 
ATOM   524   C CD2 . TYR A 1 66  ? -23.808 -22.222 -45.800 1.00 51.15  ? 66  TYR A CD2 1 
ATOM   525   C CE1 . TYR A 1 66  ? -24.944 -21.355 -48.165 1.00 47.99  ? 66  TYR A CE1 1 
ATOM   526   C CE2 . TYR A 1 66  ? -25.175 -22.332 -45.992 1.00 56.61  ? 66  TYR A CE2 1 
ATOM   527   C CZ  . TYR A 1 66  ? -25.743 -21.907 -47.183 1.00 55.59  ? 66  TYR A CZ  1 
ATOM   528   O OH  . TYR A 1 66  ? -27.103 -22.025 -47.348 1.00 57.78  ? 66  TYR A OH  1 
ATOM   529   N N   . THR A 1 67  ? -18.579 -21.571 -48.174 1.00 49.78  ? 67  THR A N   1 
ATOM   530   C CA  . THR A 1 67  ? -17.204 -21.109 -48.222 1.00 52.17  ? 67  THR A CA  1 
ATOM   531   C C   . THR A 1 67  ? -17.077 -19.730 -47.552 1.00 56.92  ? 67  THR A C   1 
ATOM   532   O O   . THR A 1 67  ? -18.048 -18.979 -47.360 1.00 52.52  ? 67  THR A O   1 
ATOM   533   C CB  . THR A 1 67  ? -16.698 -21.043 -49.672 1.00 51.83  ? 67  THR A CB  1 
ATOM   534   O OG1 . THR A 1 67  ? -17.453 -20.036 -50.351 1.00 56.72  ? 67  THR A OG1 1 
ATOM   535   C CG2 . THR A 1 67  ? -16.854 -22.344 -50.426 1.00 50.30  ? 67  THR A CG2 1 
ATOM   536   N N   . ILE A 1 68  ? -15.834 -19.366 -47.240 1.00 44.40  ? 68  ILE A N   1 
ATOM   537   C CA  . ILE A 1 68  ? -15.594 -18.068 -46.661 1.00 47.09  ? 68  ILE A CA  1 
ATOM   538   C C   . ILE A 1 68  ? -15.958 -16.992 -47.678 1.00 49.02  ? 68  ILE A C   1 
ATOM   539   O O   . ILE A 1 68  ? -16.756 -16.120 -47.333 1.00 51.72  ? 68  ILE A O   1 
ATOM   540   C CB  . ILE A 1 68  ? -14.173 -17.995 -46.072 1.00 48.56  ? 68  ILE A CB  1 
ATOM   541   C CG1 . ILE A 1 68  ? -14.169 -18.748 -44.732 1.00 44.71  ? 68  ILE A CG1 1 
ATOM   542   C CG2 . ILE A 1 68  ? -13.714 -16.544 -45.955 1.00 51.92  ? 68  ILE A CG2 1 
ATOM   543   C CD1 . ILE A 1 68  ? -12.835 -18.952 -44.135 1.00 51.52  ? 68  ILE A CD1 1 
ATOM   544   N N   . PRO A 1 69  ? -15.450 -17.005 -48.939 1.00 50.56  ? 69  PRO A N   1 
ATOM   545   C CA  . PRO A 1 69  ? -15.930 -16.056 -49.955 1.00 54.46  ? 69  PRO A CA  1 
ATOM   546   C C   . PRO A 1 69  ? -17.455 -15.936 -50.046 1.00 60.25  ? 69  PRO A C   1 
ATOM   547   O O   . PRO A 1 69  ? -17.969 -14.812 -50.086 1.00 53.62  ? 69  PRO A O   1 
ATOM   548   C CB  . PRO A 1 69  ? -15.246 -16.532 -51.239 1.00 52.75  ? 69  PRO A CB  1 
ATOM   549   C CG  . PRO A 1 69  ? -13.911 -17.062 -50.729 1.00 54.75  ? 69  PRO A CG  1 
ATOM   550   C CD  . PRO A 1 69  ? -14.263 -17.746 -49.410 1.00 53.51  ? 69  PRO A CD  1 
ATOM   551   N N   . GLU A 1 70  ? -18.187 -17.057 -49.984 1.00 55.47  ? 70  GLU A N   1 
ATOM   552   C CA  . GLU A 1 70  ? -19.639 -16.993 -50.056 1.00 54.97  ? 70  GLU A CA  1 
ATOM   553   C C   . GLU A 1 70  ? -20.191 -16.126 -48.920 1.00 60.38  ? 70  GLU A C   1 
ATOM   554   O O   . GLU A 1 70  ? -21.080 -15.310 -49.143 1.00 62.18  ? 70  GLU A O   1 
ATOM   555   C CB  . GLU A 1 70  ? -20.275 -18.389 -50.065 1.00 70.12  ? 70  GLU A CB  1 
ATOM   556   C CG  . GLU A 1 70  ? -20.114 -19.153 -51.389 1.00 73.20  ? 70  GLU A CG  1 
ATOM   557   C CD  . GLU A 1 70  ? -20.754 -20.538 -51.472 1.00 76.06  ? 70  GLU A CD  1 
ATOM   558   O OE1 . GLU A 1 70  ? -21.346 -20.864 -52.528 1.00 88.58  ? 70  GLU A OE1 1 
ATOM   559   O OE2 . GLU A 1 70  ? -20.685 -21.290 -50.489 1.00 67.44  ? 70  GLU A OE2 1 
ATOM   560   N N   . LEU A 1 71  ? -19.666 -16.282 -47.698 1.00 61.63  ? 71  LEU A N   1 
ATOM   561   C CA  . LEU A 1 71  ? -20.290 -15.675 -46.521 1.00 57.66  ? 71  LEU A CA  1 
ATOM   562   C C   . LEU A 1 71  ? -19.854 -14.223 -46.310 1.00 47.82  ? 71  LEU A C   1 
ATOM   563   O O   . LEU A 1 71  ? -20.564 -13.438 -45.675 1.00 48.27  ? 71  LEU A O   1 
ATOM   564   C CB  . LEU A 1 71  ? -19.921 -16.515 -45.303 1.00 56.82  ? 71  LEU A CB  1 
ATOM   565   C CG  . LEU A 1 71  ? -20.411 -17.962 -45.320 1.00 52.65  ? 71  LEU A CG  1 
ATOM   566   C CD1 . LEU A 1 71  ? -19.715 -18.745 -44.229 1.00 45.10  ? 71  LEU A CD1 1 
ATOM   567   C CD2 . LEU A 1 71  ? -21.917 -18.026 -45.120 1.00 52.37  ? 71  LEU A CD2 1 
ATOM   568   N N   . ARG A 1 72  ? -18.662 -13.890 -46.800 1.00 46.44  ? 72  ARG A N   1 
ATOM   569   C CA  . ARG A 1 72  ? -18.056 -12.588 -46.594 1.00 58.89  ? 72  ARG A CA  1 
ATOM   570   C C   . ARG A 1 72  ? -18.337 -11.636 -47.765 1.00 62.99  ? 72  ARG A C   1 
ATOM   571   O O   . ARG A 1 72  ? -18.703 -10.477 -47.555 1.00 59.26  ? 72  ARG A O   1 
ATOM   572   C CB  . ARG A 1 72  ? -16.549 -12.782 -46.396 1.00 59.59  ? 72  ARG A CB  1 
ATOM   573   C CG  . ARG A 1 72  ? -15.795 -11.468 -46.257 1.00 57.91  ? 72  ARG A CG  1 
ATOM   574   C CD  . ARG A 1 72  ? -14.382 -11.658 -45.763 1.00 55.93  ? 72  ARG A CD  1 
ATOM   575   N NE  . ARG A 1 72  ? -13.784 -10.349 -45.611 1.00 51.56  ? 72  ARG A NE  1 
ATOM   576   C CZ  . ARG A 1 72  ? -13.064 -9.741  -46.531 1.00 52.71  ? 72  ARG A CZ  1 
ATOM   577   N NH1 . ARG A 1 72  ? -12.914 -10.286 -47.724 1.00 61.13  ? 72  ARG A NH1 1 
ATOM   578   N NH2 . ARG A 1 72  ? -12.548 -8.559  -46.270 1.00 54.20  ? 72  ARG A NH2 1 
ATOM   579   N N   . GLU A 1 73  ? -18.099 -12.103 -48.999 1.00 72.82  ? 73  GLU A N   1 
ATOM   580   C CA  . GLU A 1 73  ? -18.328 -11.302 -50.199 1.00 79.00  ? 73  GLU A CA  1 
ATOM   581   C C   . GLU A 1 73  ? -19.575 -11.802 -50.924 1.00 76.41  ? 73  GLU A C   1 
ATOM   582   O O   . GLU A 1 73  ? -20.585 -11.115 -50.981 1.00 77.85  ? 73  GLU A O   1 
ATOM   583   C CB  . GLU A 1 73  ? -17.151 -11.387 -51.184 1.00 71.47  ? 73  GLU A CB  1 
ATOM   584   C CG  . GLU A 1 73  ? -15.775 -11.299 -50.548 1.00 80.78  ? 73  GLU A CG  1 
ATOM   585   C CD  . GLU A 1 73  ? -14.658 -10.812 -51.461 1.00 91.13  ? 73  GLU A CD  1 
ATOM   586   O OE1 . GLU A 1 73  ? -13.479 -10.836 -51.025 1.00 91.85  ? 73  GLU A OE1 1 
ATOM   587   O OE2 . GLU A 1 73  ? -14.968 -10.368 -52.588 1.00 83.48  ? 73  GLU A OE2 1 
ATOM   588   N N   . GLY A 1 74  ? -19.468 -13.044 -51.412 1.00 92.76  ? 74  GLY A N   1 
ATOM   589   C CA  . GLY A 1 74  ? -20.158 -13.529 -52.592 1.00 85.98  ? 74  GLY A CA  1 
ATOM   590   C C   . GLY A 1 74  ? -21.622 -13.841 -52.321 1.00 92.18  ? 74  GLY A C   1 
ATOM   591   O O   . GLY A 1 74  ? -22.273 -13.176 -51.516 1.00 104.00 ? 74  GLY A O   1 
ATOM   592   N N   . PRO A 1 75  ? -22.175 -14.870 -52.993 1.00 81.23  ? 75  PRO A N   1 
ATOM   593   C CA  . PRO A 1 75  ? -23.626 -14.987 -53.128 1.00 72.45  ? 75  PRO A CA  1 
ATOM   594   C C   . PRO A 1 75  ? -24.420 -15.389 -51.893 1.00 67.94  ? 75  PRO A C   1 
ATOM   595   O O   . PRO A 1 75  ? -25.625 -15.612 -51.995 1.00 65.26  ? 75  PRO A O   1 
ATOM   596   C CB  . PRO A 1 75  ? -23.814 -16.042 -54.234 1.00 76.24  ? 75  PRO A CB  1 
ATOM   597   C CG  . PRO A 1 75  ? -22.514 -16.825 -54.258 1.00 78.75  ? 75  PRO A CG  1 
ATOM   598   C CD  . PRO A 1 75  ? -21.427 -15.896 -53.741 1.00 73.67  ? 75  PRO A CD  1 
ATOM   599   N N   . HIS A 1 76  ? -23.781 -15.461 -50.721 1.00 69.32  ? 76  HIS A N   1 
ATOM   600   C CA  . HIS A 1 76  ? -24.535 -15.802 -49.517 1.00 71.03  ? 76  HIS A CA  1 
ATOM   601   C C   . HIS A 1 76  ? -24.002 -15.000 -48.330 1.00 66.38  ? 76  HIS A C   1 
ATOM   602   O O   . HIS A 1 76  ? -23.581 -15.561 -47.321 1.00 64.69  ? 76  HIS A O   1 
ATOM   603   C CB  . HIS A 1 76  ? -24.503 -17.319 -49.273 1.00 69.67  ? 76  HIS A CB  1 
ATOM   604   C CG  . HIS A 1 76  ? -25.141 -18.186 -50.321 1.00 68.89  ? 76  HIS A CG  1 
ATOM   605   N ND1 . HIS A 1 76  ? -26.508 -18.314 -50.480 1.00 69.29  ? 76  HIS A ND1 1 
ATOM   606   C CD2 . HIS A 1 76  ? -24.580 -19.023 -51.222 1.00 67.04  ? 76  HIS A CD2 1 
ATOM   607   C CE1 . HIS A 1 76  ? -26.754 -19.194 -51.446 1.00 69.10  ? 76  HIS A CE1 1 
ATOM   608   N NE2 . HIS A 1 76  ? -25.598 -19.636 -51.915 1.00 70.97  ? 76  HIS A NE2 1 
ATOM   609   N N   . LYS A 1 77  ? -24.047 -13.675 -48.451 1.00 60.04  ? 77  LYS A N   1 
ATOM   610   C CA  . LYS A 1 77  ? -23.327 -12.802 -47.540 1.00 64.04  ? 77  LYS A CA  1 
ATOM   611   C C   . LYS A 1 77  ? -24.122 -12.645 -46.245 1.00 61.43  ? 77  LYS A C   1 
ATOM   612   O O   . LYS A 1 77  ? -25.293 -12.283 -46.262 1.00 52.13  ? 77  LYS A O   1 
ATOM   613   C CB  . LYS A 1 77  ? -23.021 -11.459 -48.208 1.00 60.87  ? 77  LYS A CB  1 
ATOM   614   C CG  . LYS A 1 77  ? -22.163 -10.500 -47.401 1.00 62.09  ? 77  LYS A CG  1 
ATOM   615   C CD  . LYS A 1 77  ? -22.077 -9.120  -48.045 1.00 66.99  ? 77  LYS A CD  1 
ATOM   616   C CE  . LYS A 1 77  ? -21.401 -8.079  -47.186 1.00 60.89  ? 77  LYS A CE  1 
ATOM   617   N NZ  . LYS A 1 77  ? -20.042 -8.512  -46.797 1.00 61.19  ? 77  LYS A NZ  1 
ATOM   618   N N   . LEU A 1 78  ? -23.449 -12.924 -45.121 1.00 52.94  ? 78  LEU A N   1 
ATOM   619   C CA  . LEU A 1 78  ? -24.071 -12.853 -43.810 1.00 51.94  ? 78  LEU A CA  1 
ATOM   620   C C   . LEU A 1 78  ? -24.241 -11.396 -43.414 1.00 44.39  ? 78  LEU A C   1 
ATOM   621   O O   . LEU A 1 78  ? -23.515 -10.510 -43.889 1.00 42.35  ? 78  LEU A O   1 
ATOM   622   C CB  . LEU A 1 78  ? -23.155 -13.532 -42.786 1.00 60.54  ? 78  LEU A CB  1 
ATOM   623   C CG  . LEU A 1 78  ? -23.067 -15.052 -42.846 1.00 56.56  ? 78  LEU A CG  1 
ATOM   624   C CD1 . LEU A 1 78  ? -21.886 -15.541 -42.021 1.00 54.34  ? 78  LEU A CD1 1 
ATOM   625   C CD2 . LEU A 1 78  ? -24.366 -15.673 -42.362 1.00 53.44  ? 78  LEU A CD2 1 
ATOM   626   N N   . PRO A 1 79  ? -25.172 -11.117 -42.492 1.00 39.05  ? 79  PRO A N   1 
ATOM   627   C CA  . PRO A 1 79  ? -25.339 -9.766  -41.978 1.00 45.27  ? 79  PRO A CA  1 
ATOM   628   C C   . PRO A 1 79  ? -24.060 -9.176  -41.408 1.00 50.33  ? 79  PRO A C   1 
ATOM   629   O O   . PRO A 1 79  ? -23.291 -9.875  -40.737 1.00 51.96  ? 79  PRO A O   1 
ATOM   630   C CB  . PRO A 1 79  ? -26.416 -9.899  -40.894 1.00 41.60  ? 79  PRO A CB  1 
ATOM   631   C CG  . PRO A 1 79  ? -27.210 -11.095 -41.390 1.00 46.78  ? 79  PRO A CG  1 
ATOM   632   C CD  . PRO A 1 79  ? -26.190 -12.042 -41.984 1.00 42.59  ? 79  PRO A CD  1 
ATOM   633   N N   . THR A 1 80  ? -23.877 -7.892  -41.743 1.00 49.11  ? 80  THR A N   1 
ATOM   634   C CA  . THR A 1 80  ? -22.830 -7.039  -41.239 1.00 47.32  ? 80  THR A CA  1 
ATOM   635   C C   . THR A 1 80  ? -23.417 -6.099  -40.189 1.00 55.23  ? 80  THR A C   1 
ATOM   636   O O   . THR A 1 80  ? -24.604 -6.170  -39.874 1.00 56.28  ? 80  THR A O   1 
ATOM   637   C CB  . THR A 1 80  ? -22.197 -6.245  -42.382 1.00 54.67  ? 80  THR A CB  1 
ATOM   638   O OG1 . THR A 1 80  ? -22.987 -5.076  -42.622 1.00 53.74  ? 80  THR A OG1 1 
ATOM   639   C CG2 . THR A 1 80  ? -22.023 -7.068  -43.639 1.00 54.17  ? 80  THR A CG2 1 
ATOM   640   N N   . ALA A 1 81  ? -22.555 -5.244  -39.619 1.00 57.19  ? 81  ALA A N   1 
ATOM   641   C CA  . ALA A 1 81  ? -22.999 -4.217  -38.695 1.00 58.27  ? 81  ALA A CA  1 
ATOM   642   C C   . ALA A 1 81  ? -23.445 -3.025  -39.525 1.00 56.18  ? 81  ALA A C   1 
ATOM   643   O O   . ALA A 1 81  ? -23.093 -2.935  -40.698 1.00 51.70  ? 81  ALA A O   1 
ATOM   644   C CB  . ALA A 1 81  ? -21.885 -3.832  -37.751 1.00 57.12  ? 81  ALA A CB  1 
ATOM   645   N N   . GLU A 1 82  ? -24.162 -2.101  -38.888 1.00 60.47  ? 82  GLU A N   1 
ATOM   646   C CA  . GLU A 1 82  ? -24.657 -0.922  -39.578 1.00 66.06  ? 82  GLU A CA  1 
ATOM   647   C C   . GLU A 1 82  ? -23.484 -0.125  -40.150 1.00 56.98  ? 82  GLU A C   1 
ATOM   648   O O   . GLU A 1 82  ? -22.618 0.355   -39.423 1.00 65.67  ? 82  GLU A O   1 
ATOM   649   C CB  . GLU A 1 82  ? -25.509 -0.105  -38.608 1.00 75.67  ? 82  GLU A CB  1 
ATOM   650   C CG  . GLU A 1 82  ? -26.429 0.896   -39.287 1.00 87.94  ? 82  GLU A CG  1 
ATOM   651   C CD  . GLU A 1 82  ? -27.108 1.856   -38.321 1.00 90.57  ? 82  GLU A CD  1 
ATOM   652   O OE1 . GLU A 1 82  ? -26.621 3.002   -38.197 1.00 89.68  ? 82  GLU A OE1 1 
ATOM   653   O OE2 . GLU A 1 82  ? -28.112 1.457   -37.690 1.00 91.81  ? 82  GLU A OE2 1 
ATOM   654   N N   . GLY A 1 83  ? -23.438 -0.022  -41.475 1.00 55.94  ? 83  GLY A N   1 
ATOM   655   C CA  . GLY A 1 83  ? -22.341 0.639   -42.164 1.00 57.99  ? 83  GLY A CA  1 
ATOM   656   C C   . GLY A 1 83  ? -21.135 -0.262  -42.443 1.00 61.54  ? 83  GLY A C   1 
ATOM   657   O O   . GLY A 1 83  ? -20.175 0.177   -43.074 1.00 57.46  ? 83  GLY A O   1 
ATOM   658   N N   . GLY A 1 84  ? -21.176 -1.528  -42.002 1.00 67.89  ? 84  GLY A N   1 
ATOM   659   C CA  . GLY A 1 84  ? -20.012 -2.400  -42.093 1.00 62.72  ? 84  GLY A CA  1 
ATOM   660   C C   . GLY A 1 84  ? -20.064 -3.371  -43.273 1.00 60.64  ? 84  GLY A C   1 
ATOM   661   O O   . GLY A 1 84  ? -21.129 -3.642  -43.828 1.00 73.69  ? 84  GLY A O   1 
ATOM   662   N N   . PHE A 1 85  ? -18.891 -3.926  -43.595 1.00 53.78  ? 85  PHE A N   1 
ATOM   663   C CA  . PHE A 1 85  ? -18.718 -4.963  -44.597 1.00 55.49  ? 85  PHE A CA  1 
ATOM   664   C C   . PHE A 1 85  ? -18.520 -6.352  -43.969 1.00 56.70  ? 85  PHE A C   1 
ATOM   665   O O   . PHE A 1 85  ? -19.030 -7.370  -44.451 1.00 53.78  ? 85  PHE A O   1 
ATOM   666   C CB  . PHE A 1 85  ? -17.482 -4.649  -45.439 1.00 60.37  ? 85  PHE A CB  1 
ATOM   667   C CG  . PHE A 1 85  ? -17.248 -5.634  -46.553 1.00 72.27  ? 85  PHE A CG  1 
ATOM   668   C CD1 . PHE A 1 85  ? -18.068 -5.644  -47.676 1.00 73.99  ? 85  PHE A CD1 1 
ATOM   669   C CD2 . PHE A 1 85  ? -16.235 -6.583  -46.464 1.00 74.91  ? 85  PHE A CD2 1 
ATOM   670   C CE1 . PHE A 1 85  ? -17.859 -6.567  -48.693 1.00 74.51  ? 85  PHE A CE1 1 
ATOM   671   C CE2 . PHE A 1 85  ? -16.026 -7.498  -47.486 1.00 66.06  ? 85  PHE A CE2 1 
ATOM   672   C CZ  . PHE A 1 85  ? -16.836 -7.489  -48.597 1.00 68.78  ? 85  PHE A CZ  1 
ATOM   673   N N   . GLU A 1 86  ? -17.724 -6.414  -42.904 1.00 53.16  ? 86  GLU A N   1 
ATOM   674   C CA  . GLU A 1 86  ? -17.260 -7.693  -42.398 1.00 47.75  ? 86  GLU A CA  1 
ATOM   675   C C   . GLU A 1 86  ? -18.417 -8.396  -41.716 1.00 44.89  ? 86  GLU A C   1 
ATOM   676   O O   . GLU A 1 86  ? -19.239 -7.753  -41.075 1.00 48.23  ? 86  GLU A O   1 
ATOM   677   C CB  . GLU A 1 86  ? -16.063 -7.496  -41.475 1.00 53.31  ? 86  GLU A CB  1 
ATOM   678   C CG  . GLU A 1 86  ? -14.860 -6.884  -42.185 1.00 53.68  ? 86  GLU A CG  1 
ATOM   679   C CD  . GLU A 1 86  ? -14.347 -7.678  -43.375 1.00 57.03  ? 86  GLU A CD  1 
ATOM   680   O OE1 . GLU A 1 86  ? -13.409 -7.205  -44.041 1.00 58.81  ? 86  GLU A OE1 1 
ATOM   681   O OE2 . GLU A 1 86  ? -14.866 -8.786  -43.616 1.00 54.78  ? 86  GLU A OE2 1 
ATOM   682   N N   . PRO A 1 87  ? -18.556 -9.727  -41.896 1.00 41.55  ? 87  PRO A N   1 
ATOM   683   C CA  . PRO A 1 87  ? -19.664 -10.474 -41.319 1.00 41.61  ? 87  PRO A CA  1 
ATOM   684   C C   . PRO A 1 87  ? -19.592 -10.521 -39.803 1.00 45.55  ? 87  PRO A C   1 
ATOM   685   O O   . PRO A 1 87  ? -18.509 -10.629 -39.240 1.00 42.38  ? 87  PRO A O   1 
ATOM   686   C CB  . PRO A 1 87  ? -19.475 -11.893 -41.848 1.00 44.99  ? 87  PRO A CB  1 
ATOM   687   C CG  . PRO A 1 87  ? -18.054 -11.977 -42.241 1.00 40.26  ? 87  PRO A CG  1 
ATOM   688   C CD  . PRO A 1 87  ? -17.628 -10.579 -42.621 1.00 39.52  ? 87  PRO A CD  1 
ATOM   689   N N   . LEU A 1 88  ? -20.757 -10.439 -39.163 1.00 46.81  ? 88  LEU A N   1 
ATOM   690   C CA  . LEU A 1 88  ? -20.820 -10.534 -37.723 1.00 46.79  ? 88  LEU A CA  1 
ATOM   691   C C   . LEU A 1 88  ? -20.700 -11.996 -37.323 1.00 49.86  ? 88  LEU A C   1 
ATOM   692   O O   . LEU A 1 88  ? -21.375 -12.870 -37.874 1.00 45.99  ? 88  LEU A O   1 
ATOM   693   C CB  . LEU A 1 88  ? -22.136 -9.949  -37.210 1.00 47.68  ? 88  LEU A CB  1 
ATOM   694   C CG  . LEU A 1 88  ? -22.296 -8.444  -37.389 1.00 46.92  ? 88  LEU A CG  1 
ATOM   695   C CD1 . LEU A 1 88  ? -23.580 -7.996  -36.725 1.00 51.58  ? 88  LEU A CD1 1 
ATOM   696   C CD2 . LEU A 1 88  ? -21.119 -7.688  -36.795 1.00 51.21  ? 88  LEU A CD2 1 
ATOM   697   N N   . PRO A 1 89  ? -19.851 -12.297 -36.318 1.00 49.38  ? 89  PRO A N   1 
ATOM   698   C CA  . PRO A 1 89  ? -19.761 -13.659 -35.790 1.00 46.64  ? 89  PRO A CA  1 
ATOM   699   C C   . PRO A 1 89  ? -21.055 -14.204 -35.192 1.00 42.41  ? 89  PRO A C   1 
ATOM   700   O O   . PRO A 1 89  ? -21.289 -15.399 -35.253 1.00 44.08  ? 89  PRO A O   1 
ATOM   701   C CB  . PRO A 1 89  ? -18.674 -13.526 -34.729 1.00 46.97  ? 89  PRO A CB  1 
ATOM   702   C CG  . PRO A 1 89  ? -18.688 -12.076 -34.366 1.00 52.43  ? 89  PRO A CG  1 
ATOM   703   C CD  . PRO A 1 89  ? -18.937 -11.353 -35.663 1.00 44.50  ? 89  PRO A CD  1 
ATOM   704   N N   . GLU A 1 90  ? -21.901 -13.324 -34.636 1.00 45.48  ? 90  GLU A N   1 
ATOM   705   C CA  . GLU A 1 90  ? -23.225 -13.703 -34.134 1.00 47.38  ? 90  GLU A CA  1 
ATOM   706   C C   . GLU A 1 90  ? -24.023 -14.459 -35.206 1.00 45.49  ? 90  GLU A C   1 
ATOM   707   O O   . GLU A 1 90  ? -24.727 -15.424 -34.905 1.00 46.44  ? 90  GLU A O   1 
ATOM   708   C CB  . GLU A 1 90  ? -24.028 -12.487 -33.638 1.00 44.40  ? 90  GLU A CB  1 
ATOM   709   C CG  . GLU A 1 90  ? -23.433 -11.749 -32.417 1.00 45.22  ? 90  GLU A CG  1 
ATOM   710   C CD  . GLU A 1 90  ? -22.649 -10.482 -32.717 1.00 44.80  ? 90  GLU A CD  1 
ATOM   711   O OE1 . GLU A 1 90  ? -22.903 -9.457  -32.082 1.00 47.22  ? 90  GLU A OE1 1 
ATOM   712   O OE2 . GLU A 1 90  ? -21.781 -10.516 -33.595 1.00 48.96  ? 90  GLU A OE2 1 
ATOM   713   N N   . GLY A 1 91  ? -23.933 -14.016 -36.458 1.00 45.57  ? 91  GLY A N   1 
ATOM   714   C CA  . GLY A 1 91  ? -24.705 -14.637 -37.517 1.00 47.99  ? 91  GLY A CA  1 
ATOM   715   C C   . GLY A 1 91  ? -24.077 -15.947 -37.976 1.00 49.32  ? 91  GLY A C   1 
ATOM   716   O O   . GLY A 1 91  ? -24.782 -16.888 -38.361 1.00 45.58  ? 91  GLY A O   1 
ATOM   717   N N   . LEU A 1 92  ? -22.743 -15.980 -37.975 1.00 45.84  ? 92  LEU A N   1 
ATOM   718   C CA  . LEU A 1 92  ? -22.042 -17.209 -38.276 1.00 47.00  ? 92  LEU A CA  1 
ATOM   719   C C   . LEU A 1 92  ? -22.419 -18.282 -37.253 1.00 48.01  ? 92  LEU A C   1 
ATOM   720   O O   . LEU A 1 92  ? -22.616 -19.431 -37.633 1.00 46.74  ? 92  LEU A O   1 
ATOM   721   C CB  . LEU A 1 92  ? -20.530 -16.977 -38.295 1.00 50.32  ? 92  LEU A CB  1 
ATOM   722   C CG  . LEU A 1 92  ? -19.708 -18.267 -38.355 1.00 54.55  ? 92  LEU A CG  1 
ATOM   723   C CD1 . LEU A 1 92  ? -20.034 -19.047 -39.622 1.00 48.51  ? 92  LEU A CD1 1 
ATOM   724   C CD2 . LEU A 1 92  ? -18.223 -17.973 -38.292 1.00 59.82  ? 92  LEU A CD2 1 
ATOM   725   N N   . TRP A 1 93  ? -22.503 -17.927 -35.963 1.00 43.96  ? 93  TRP A N   1 
ATOM   726   C CA  . TRP A 1 93  ? -22.923 -18.889 -34.944 1.00 44.90  ? 93  TRP A CA  1 
ATOM   727   C C   . TRP A 1 93  ? -24.297 -19.473 -35.269 1.00 43.77  ? 93  TRP A C   1 
ATOM   728   O O   . TRP A 1 93  ? -24.546 -20.653 -35.034 1.00 48.47  ? 93  TRP A O   1 
ATOM   729   C CB  . TRP A 1 93  ? -22.949 -18.223 -33.563 1.00 43.72  ? 93  TRP A CB  1 
ATOM   730   C CG  . TRP A 1 93  ? -22.991 -19.157 -32.395 1.00 37.85  ? 93  TRP A CG  1 
ATOM   731   C CD1 . TRP A 1 93  ? -22.081 -20.121 -32.112 1.00 41.22  ? 93  TRP A CD1 1 
ATOM   732   C CD2 . TRP A 1 93  ? -23.891 -19.135 -31.279 1.00 38.36  ? 93  TRP A CD2 1 
ATOM   733   N NE1 . TRP A 1 93  ? -22.377 -20.731 -30.925 1.00 40.16  ? 93  TRP A NE1 1 
ATOM   734   C CE2 . TRP A 1 93  ? -23.467 -20.135 -30.379 1.00 36.27  ? 93  TRP A CE2 1 
ATOM   735   C CE3 . TRP A 1 93  ? -25.025 -18.381 -30.949 1.00 43.31  ? 93  TRP A CE3 1 
ATOM   736   C CZ2 . TRP A 1 93  ? -24.132 -20.420 -29.191 1.00 36.76  ? 93  TRP A CZ2 1 
ATOM   737   C CZ3 . TRP A 1 93  ? -25.660 -18.623 -29.745 1.00 41.69  ? 93  TRP A CZ3 1 
ATOM   738   C CH2 . TRP A 1 93  ? -25.223 -19.633 -28.886 1.00 38.62  ? 93  TRP A CH2 1 
ATOM   739   N N   . TYR A 1 94  ? -25.223 -18.634 -35.763 1.00 55.23  ? 94  TYR A N   1 
ATOM   740   C CA  . TYR A 1 94  ? -26.567 -19.114 -36.110 1.00 48.20  ? 94  TYR A CA  1 
ATOM   741   C C   . TYR A 1 94  ? -26.400 -20.178 -37.181 1.00 43.25  ? 94  TYR A C   1 
ATOM   742   O O   . TYR A 1 94  ? -26.941 -21.268 -37.050 1.00 43.72  ? 94  TYR A O   1 
ATOM   743   C CB  . TYR A 1 94  ? -27.489 -17.965 -36.536 1.00 50.99  ? 94  TYR A CB  1 
ATOM   744   C CG  . TYR A 1 94  ? -28.928 -18.314 -36.859 1.00 51.10  ? 94  TYR A CG  1 
ATOM   745   C CD1 . TYR A 1 94  ? -29.271 -18.903 -38.068 1.00 56.29  ? 94  TYR A CD1 1 
ATOM   746   C CD2 . TYR A 1 94  ? -29.952 -18.024 -35.982 1.00 44.83  ? 94  TYR A CD2 1 
ATOM   747   C CE1 . TYR A 1 94  ? -30.584 -19.206 -38.391 1.00 58.92  ? 94  TYR A CE1 1 
ATOM   748   C CE2 . TYR A 1 94  ? -31.275 -18.329 -36.284 1.00 61.73  ? 94  TYR A CE2 1 
ATOM   749   C CZ  . TYR A 1 94  ? -31.596 -18.908 -37.502 1.00 58.70  ? 94  TYR A CZ  1 
ATOM   750   O OH  . TYR A 1 94  ? -32.883 -19.232 -37.835 1.00 62.52  ? 94  TYR A OH  1 
ATOM   751   N N   . LEU A 1 95  ? -25.544 -19.875 -38.169 1.00 39.17  ? 95  LEU A N   1 
ATOM   752   C CA  . LEU A 1 95  ? -25.299 -20.784 -39.271 1.00 40.94  ? 95  LEU A CA  1 
ATOM   753   C C   . LEU A 1 95  ? -24.787 -22.111 -38.751 1.00 45.34  ? 95  LEU A C   1 
ATOM   754   O O   . LEU A 1 95  ? -25.303 -23.138 -39.174 1.00 48.34  ? 95  LEU A O   1 
ATOM   755   C CB  . LEU A 1 95  ? -24.307 -20.173 -40.273 1.00 43.85  ? 95  LEU A CB  1 
ATOM   756   C CG  . LEU A 1 95  ? -23.905 -21.094 -41.424 1.00 42.24  ? 95  LEU A CG  1 
ATOM   757   C CD1 . LEU A 1 95  ? -25.120 -21.648 -42.136 1.00 43.67  ? 95  LEU A CD1 1 
ATOM   758   C CD2 . LEU A 1 95  ? -23.031 -20.367 -42.399 1.00 41.57  ? 95  LEU A CD2 1 
ATOM   759   N N   . LEU A 1 96  ? -23.747 -22.049 -37.889 1.00 48.81  ? 96  LEU A N   1 
ATOM   760   C CA  . LEU A 1 96  ? -23.072 -23.216 -37.352 1.00 40.71  ? 96  LEU A CA  1 
ATOM   761   C C   . LEU A 1 96  ? -24.108 -24.098 -36.671 1.00 40.06  ? 96  LEU A C   1 
ATOM   762   O O   . LEU A 1 96  ? -24.086 -25.307 -36.838 1.00 44.40  ? 96  LEU A O   1 
ATOM   763   C CB  . LEU A 1 96  ? -21.995 -22.798 -36.338 1.00 42.55  ? 96  LEU A CB  1 
ATOM   764   C CG  . LEU A 1 96  ? -20.764 -22.083 -36.882 1.00 41.46  ? 96  LEU A CG  1 
ATOM   765   C CD1 . LEU A 1 96  ? -19.652 -22.020 -35.845 1.00 42.82  ? 96  LEU A CD1 1 
ATOM   766   C CD2 . LEU A 1 96  ? -20.250 -22.739 -38.142 1.00 47.13  ? 96  LEU A CD2 1 
ATOM   767   N N   . LEU A 1 97  ? -24.994 -23.480 -35.885 1.00 43.19  ? 97  LEU A N   1 
ATOM   768   C CA  . LEU A 1 97  ? -25.935 -24.239 -35.071 1.00 48.66  ? 97  LEU A CA  1 
ATOM   769   C C   . LEU A 1 97  ? -27.014 -24.901 -35.927 1.00 50.62  ? 97  LEU A C   1 
ATOM   770   O O   . LEU A 1 97  ? -27.344 -26.066 -35.692 1.00 51.64  ? 97  LEU A O   1 
ATOM   771   C CB  . LEU A 1 97  ? -26.557 -23.334 -33.992 1.00 41.01  ? 97  LEU A CB  1 
ATOM   772   C CG  . LEU A 1 97  ? -25.706 -23.239 -32.720 1.00 45.08  ? 97  LEU A CG  1 
ATOM   773   C CD1 . LEU A 1 97  ? -26.262 -22.233 -31.693 1.00 43.97  ? 97  LEU A CD1 1 
ATOM   774   C CD2 . LEU A 1 97  ? -25.558 -24.620 -32.097 1.00 40.73  ? 97  LEU A CD2 1 
ATOM   775   N N   . THR A 1 98  ? -27.582 -24.150 -36.878 1.00 44.88  ? 98  THR A N   1 
ATOM   776   C CA  . THR A 1 98  ? -28.832 -24.555 -37.501 1.00 45.50  ? 98  THR A CA  1 
ATOM   777   C C   . THR A 1 98  ? -28.629 -25.110 -38.896 1.00 45.34  ? 98  THR A C   1 
ATOM   778   O O   . THR A 1 98  ? -29.548 -25.705 -39.398 1.00 45.52  ? 98  THR A O   1 
ATOM   779   C CB  . THR A 1 98  ? -29.833 -23.410 -37.626 1.00 44.10  ? 98  THR A CB  1 
ATOM   780   O OG1 . THR A 1 98  ? -29.219 -22.377 -38.395 1.00 46.16  ? 98  THR A OG1 1 
ATOM   781   C CG2 . THR A 1 98  ? -30.288 -22.931 -36.269 1.00 49.71  ? 98  THR A CG2 1 
ATOM   782   N N   . GLY A 1 99  ? -27.454 -24.896 -39.494 1.00 48.04  ? 99  GLY A N   1 
ATOM   783   C CA  . GLY A 1 99  ? -27.205 -25.212 -40.888 1.00 48.32  ? 99  GLY A CA  1 
ATOM   784   C C   . GLY A 1 99  ? -27.844 -24.230 -41.875 1.00 51.25  ? 99  GLY A C   1 
ATOM   785   O O   . GLY A 1 99  ? -27.806 -24.505 -43.067 1.00 55.83  ? 99  GLY A O   1 
ATOM   786   N N   . GLU A 1 100 ? -28.389 -23.103 -41.389 1.00 50.15  ? 100 GLU A N   1 
ATOM   787   C CA  . GLU A 1 100 ? -29.218 -22.173 -42.156 1.00 49.39  ? 100 GLU A CA  1 
ATOM   788   C C   . GLU A 1 100 ? -28.693 -20.736 -42.037 1.00 53.47  ? 100 GLU A C   1 
ATOM   789   O O   . GLU A 1 100 ? -28.327 -20.287 -40.951 1.00 57.87  ? 100 GLU A O   1 
ATOM   790   C CB  . GLU A 1 100 ? -30.654 -22.153 -41.613 1.00 53.14  ? 100 GLU A CB  1 
ATOM   791   C CG  . GLU A 1 100 ? -31.425 -23.475 -41.717 1.00 60.26  ? 100 GLU A CG  1 
ATOM   792   C CD  . GLU A 1 100 ? -32.814 -23.458 -41.067 1.00 71.90  ? 100 GLU A CD  1 
ATOM   793   O OE1 . GLU A 1 100 ? -33.549 -24.511 -41.120 1.00 58.99  ? 100 GLU A OE1 1 
ATOM   794   O OE2 . GLU A 1 100 ? -33.180 -22.388 -40.494 1.00 73.14  ? 100 GLU A OE2 1 
ATOM   795   N N   . LEU A 1 101 ? -28.730 -19.973 -43.140 1.00 50.92  ? 101 LEU A N   1 
ATOM   796   C CA  . LEU A 1 101 ? -28.303 -18.584 -43.144 1.00 46.71  ? 101 LEU A CA  1 
ATOM   797   C C   . LEU A 1 101 ? -29.292 -17.750 -42.357 1.00 51.00  ? 101 LEU A C   1 
ATOM   798   O O   . LEU A 1 101 ? -30.487 -17.924 -42.517 1.00 58.43  ? 101 LEU A O   1 
ATOM   799   C CB  . LEU A 1 101 ? -28.196 -18.084 -44.574 1.00 49.68  ? 101 LEU A CB  1 
ATOM   800   C CG  . LEU A 1 101 ? -27.184 -18.850 -45.418 1.00 52.91  ? 101 LEU A CG  1 
ATOM   801   C CD1 . LEU A 1 101 ? -27.511 -18.714 -46.893 1.00 51.64  ? 101 LEU A CD1 1 
ATOM   802   C CD2 . LEU A 1 101 ? -25.775 -18.366 -45.126 1.00 48.95  ? 101 LEU A CD2 1 
ATOM   803   N N   . PRO A 1 102 ? -28.825 -16.862 -41.453 1.00 49.31  ? 102 PRO A N   1 
ATOM   804   C CA  . PRO A 1 102 ? -29.734 -16.061 -40.628 1.00 49.90  ? 102 PRO A CA  1 
ATOM   805   C C   . PRO A 1 102 ? -30.216 -14.827 -41.385 1.00 46.38  ? 102 PRO A C   1 
ATOM   806   O O   . PRO A 1 102 ? -29.554 -14.396 -42.320 1.00 48.61  ? 102 PRO A O   1 
ATOM   807   C CB  . PRO A 1 102 ? -28.837 -15.607 -39.461 1.00 44.07  ? 102 PRO A CB  1 
ATOM   808   C CG  . PRO A 1 102 ? -27.452 -15.463 -40.135 1.00 44.27  ? 102 PRO A CG  1 
ATOM   809   C CD  . PRO A 1 102 ? -27.403 -16.592 -41.162 1.00 42.46  ? 102 PRO A CD  1 
ATOM   810   N N   . THR A 1 103 ? -31.336 -14.266 -40.933 1.00 47.73  ? 103 THR A N   1 
ATOM   811   C CA  . THR A 1 103 ? -31.788 -12.946 -41.344 1.00 62.11  ? 103 THR A CA  1 
ATOM   812   C C   . THR A 1 103 ? -31.105 -11.911 -40.462 1.00 63.95  ? 103 THR A C   1 
ATOM   813   O O   . THR A 1 103 ? -30.358 -12.277 -39.550 1.00 53.14  ? 103 THR A O   1 
ATOM   814   C CB  . THR A 1 103 ? -33.316 -12.782 -41.226 1.00 67.13  ? 103 THR A CB  1 
ATOM   815   O OG1 . THR A 1 103 ? -33.661 -12.946 -39.843 1.00 63.64  ? 103 THR A OG1 1 
ATOM   816   C CG2 . THR A 1 103 ? -34.092 -13.748 -42.107 1.00 61.34  ? 103 THR A CG2 1 
ATOM   817   N N   . GLU A 1 104 ? -31.381 -10.634 -40.763 1.00 64.31  ? 104 GLU A N   1 
ATOM   818   C CA  . GLU A 1 104 ? -30.981 -9.511  -39.935 1.00 68.59  ? 104 GLU A CA  1 
ATOM   819   C C   . GLU A 1 104 ? -31.583 -9.648  -38.536 1.00 66.70  ? 104 GLU A C   1 
ATOM   820   O O   . GLU A 1 104 ? -30.919 -9.363  -37.545 1.00 67.55  ? 104 GLU A O   1 
ATOM   821   C CB  . GLU A 1 104 ? -31.421 -8.205  -40.595 1.00 78.87  ? 104 GLU A CB  1 
ATOM   822   C CG  . GLU A 1 104 ? -30.337 -7.540  -41.424 1.00 92.55  ? 104 GLU A CG  1 
ATOM   823   C CD  . GLU A 1 104 ? -29.375 -6.682  -40.616 1.00 104.87 ? 104 GLU A CD  1 
ATOM   824   O OE1 . GLU A 1 104 ? -28.160 -6.703  -40.908 1.00 114.83 ? 104 GLU A OE1 1 
ATOM   825   O OE2 . GLU A 1 104 ? -29.842 -6.001  -39.680 1.00 114.22 ? 104 GLU A OE2 1 
ATOM   826   N N   . GLU A 1 105 ? -32.845 -10.075 -38.470 1.00 64.06  ? 105 GLU A N   1 
ATOM   827   C CA  . GLU A 1 105 ? -33.579 -10.179 -37.223 1.00 72.07  ? 105 GLU A CA  1 
ATOM   828   C C   . GLU A 1 105 ? -32.960 -11.265 -36.357 1.00 68.18  ? 105 GLU A C   1 
ATOM   829   O O   . GLU A 1 105 ? -32.853 -11.091 -35.150 1.00 68.72  ? 105 GLU A O   1 
ATOM   830   C CB  . GLU A 1 105 ? -35.045 -10.525 -37.491 1.00 87.57  ? 105 GLU A CB  1 
ATOM   831   C CG  . GLU A 1 105 ? -35.939 -10.502 -36.257 1.00 100.14 ? 105 GLU A CG  1 
ATOM   832   C CD  . GLU A 1 105 ? -37.386 -10.912 -36.524 1.00 117.07 ? 105 GLU A CD  1 
ATOM   833   O OE1 . GLU A 1 105 ? -37.911 -11.757 -35.765 1.00 122.98 ? 105 GLU A OE1 1 
ATOM   834   O OE2 . GLU A 1 105 ? -37.992 -10.396 -37.502 1.00 95.20  ? 105 GLU A OE2 1 
ATOM   835   N N   . ASP A 1 106 ? -32.591 -12.387 -36.984 1.00 68.98  ? 106 ASP A N   1 
ATOM   836   C CA  . ASP A 1 106 ? -31.975 -13.506 -36.286 1.00 66.73  ? 106 ASP A CA  1 
ATOM   837   C C   . ASP A 1 106 ? -30.701 -13.019 -35.592 1.00 64.08  ? 106 ASP A C   1 
ATOM   838   O O   . ASP A 1 106 ? -30.512 -13.253 -34.398 1.00 54.31  ? 106 ASP A O   1 
ATOM   839   C CB  . ASP A 1 106 ? -31.665 -14.657 -37.256 1.00 64.34  ? 106 ASP A CB  1 
ATOM   840   C CG  . ASP A 1 106 ? -32.868 -15.206 -38.024 1.00 67.48  ? 106 ASP A CG  1 
ATOM   841   O OD1 . ASP A 1 106 ? -33.987 -14.957 -37.566 1.00 66.63  ? 106 ASP A OD1 1 
ATOM   842   O OD2 . ASP A 1 106 ? -32.675 -15.867 -39.099 1.00 52.61  ? 106 ASP A OD2 1 
ATOM   843   N N   . VAL A 1 107 ? -29.837 -12.341 -36.368 1.00 58.20  ? 107 VAL A N   1 
ATOM   844   C CA  . VAL A 1 107 ? -28.560 -11.860 -35.884 1.00 53.92  ? 107 VAL A CA  1 
ATOM   845   C C   . VAL A 1 107 ? -28.796 -10.880 -34.736 1.00 54.79  ? 107 VAL A C   1 
ATOM   846   O O   . VAL A 1 107 ? -28.144 -10.977 -33.700 1.00 54.47  ? 107 VAL A O   1 
ATOM   847   C CB  . VAL A 1 107 ? -27.725 -11.226 -37.010 1.00 54.80  ? 107 VAL A CB  1 
ATOM   848   C CG1 . VAL A 1 107 ? -26.521 -10.472 -36.476 1.00 59.49  ? 107 VAL A CG1 1 
ATOM   849   C CG2 . VAL A 1 107 ? -27.266 -12.253 -38.016 1.00 50.44  ? 107 VAL A CG2 1 
ATOM   850   N N   . LYS A 1 108 ? -29.717 -9.936  -34.924 1.00 58.16  ? 108 LYS A N   1 
ATOM   851   C CA  . LYS A 1 108 ? -29.949 -8.897  -33.937 1.00 57.82  ? 108 LYS A CA  1 
ATOM   852   C C   . LYS A 1 108 ? -30.379 -9.528  -32.622 1.00 49.57  ? 108 LYS A C   1 
ATOM   853   O O   . LYS A 1 108 ? -30.028 -9.013  -31.570 1.00 50.83  ? 108 LYS A O   1 
ATOM   854   C CB  . LYS A 1 108 ? -31.020 -7.875  -34.344 1.00 73.99  ? 108 LYS A CB  1 
ATOM   855   C CG  . LYS A 1 108 ? -30.580 -6.715  -35.238 1.00 81.46  ? 108 LYS A CG  1 
ATOM   856   C CD  . LYS A 1 108 ? -31.409 -5.443  -34.991 1.00 93.78  ? 108 LYS A CD  1 
ATOM   857   C CE  . LYS A 1 108 ? -31.946 -4.769  -36.240 1.00 94.43  ? 108 LYS A CE  1 
ATOM   858   N NZ  . LYS A 1 108 ? -30.864 -4.412  -37.185 1.00 90.43  ? 108 LYS A NZ  1 
ATOM   859   N N   . GLU A 1 109 ? -31.153 -10.614 -32.684 1.00 55.68  ? 109 GLU A N   1 
ATOM   860   C CA  . GLU A 1 109 ? -31.673 -11.260 -31.486 1.00 55.17  ? 109 GLU A CA  1 
ATOM   861   C C   . GLU A 1 109 ? -30.528 -11.854 -30.670 1.00 56.22  ? 109 GLU A C   1 
ATOM   862   O O   . GLU A 1 109 ? -30.591 -11.846 -29.449 1.00 63.70  ? 109 GLU A O   1 
ATOM   863   C CB  . GLU A 1 109 ? -32.685 -12.351 -31.843 1.00 62.62  ? 109 GLU A CB  1 
ATOM   864   C CG  . GLU A 1 109 ? -34.135 -11.913 -31.750 1.00 76.98  ? 109 GLU A CG  1 
ATOM   865   C CD  . GLU A 1 109 ? -35.178 -12.953 -32.150 1.00 89.23  ? 109 GLU A CD  1 
ATOM   866   O OE1 . GLU A 1 109 ? -36.373 -12.775 -31.771 1.00 96.14  ? 109 GLU A OE1 1 
ATOM   867   O OE2 . GLU A 1 109 ? -34.814 -13.924 -32.863 1.00 72.41  ? 109 GLU A OE2 1 
ATOM   868   N N   . ILE A 1 110 ? -29.506 -12.385 -31.359 1.00 54.14  ? 110 ILE A N   1 
ATOM   869   C CA  . ILE A 1 110 ? -28.356 -12.998 -30.717 1.00 50.31  ? 110 ILE A CA  1 
ATOM   870   C C   . ILE A 1 110 ? -27.454 -11.922 -30.113 1.00 51.36  ? 110 ILE A C   1 
ATOM   871   O O   . ILE A 1 110 ? -27.030 -12.060 -28.974 1.00 43.47  ? 110 ILE A O   1 
ATOM   872   C CB  . ILE A 1 110 ? -27.568 -13.877 -31.694 1.00 48.56  ? 110 ILE A CB  1 
ATOM   873   C CG1 . ILE A 1 110 ? -28.353 -15.123 -32.115 1.00 53.40  ? 110 ILE A CG1 1 
ATOM   874   C CG2 . ILE A 1 110 ? -26.216 -14.244 -31.106 1.00 50.97  ? 110 ILE A CG2 1 
ATOM   875   C CD1 . ILE A 1 110 ? -27.754 -15.828 -33.322 1.00 52.65  ? 110 ILE A CD1 1 
ATOM   876   N N   . SER A 1 111 ? -27.143 -10.869 -30.872 1.00 47.36  ? 111 SER A N   1 
ATOM   877   C CA  . SER A 1 111 ? -26.408 -9.746  -30.320 1.00 52.23  ? 111 SER A CA  1 
ATOM   878   C C   . SER A 1 111 ? -27.036 -9.276  -29.011 1.00 48.67  ? 111 SER A C   1 
ATOM   879   O O   . SER A 1 111 ? -26.325 -9.054  -28.049 1.00 51.68  ? 111 SER A O   1 
ATOM   880   C CB  . SER A 1 111 ? -26.298 -8.609  -31.301 1.00 47.88  ? 111 SER A CB  1 
ATOM   881   O OG  . SER A 1 111 ? -25.510 -9.009  -32.405 1.00 52.45  ? 111 SER A OG  1 
ATOM   882   N N   . ALA A 1 112 ? -28.356 -9.102  -28.995 1.00 47.61  ? 112 ALA A N   1 
ATOM   883   C CA  . ALA A 1 112 ? -29.053 -8.544  -27.850 1.00 51.06  ? 112 ALA A CA  1 
ATOM   884   C C   . ALA A 1 112 ? -28.913 -9.490  -26.669 1.00 53.58  ? 112 ALA A C   1 
ATOM   885   O O   . ALA A 1 112 ? -28.952 -9.054  -25.519 1.00 53.75  ? 112 ALA A O   1 
ATOM   886   C CB  . ALA A 1 112 ? -30.527 -8.360  -28.167 1.00 51.74  ? 112 ALA A CB  1 
ATOM   887   N N   . GLU A 1 113 ? -28.905 -10.792 -26.990 1.00 52.52  ? 113 GLU A N   1 
ATOM   888   C CA  . GLU A 1 113 ? -28.753 -11.845 -25.999 1.00 53.20  ? 113 GLU A CA  1 
ATOM   889   C C   . GLU A 1 113 ? -27.331 -11.758 -25.426 1.00 48.71  ? 113 GLU A C   1 
ATOM   890   O O   . GLU A 1 113 ? -27.137 -11.780 -24.223 1.00 54.29  ? 113 GLU A O   1 
ATOM   891   C CB  . GLU A 1 113 ? -29.099 -13.168 -26.686 1.00 60.30  ? 113 GLU A CB  1 
ATOM   892   C CG  . GLU A 1 113 ? -29.844 -14.174 -25.842 1.00 63.52  ? 113 GLU A CG  1 
ATOM   893   C CD  . GLU A 1 113 ? -30.977 -13.632 -24.990 1.00 67.47  ? 113 GLU A CD  1 
ATOM   894   O OE1 . GLU A 1 113 ? -30.870 -13.718 -23.746 1.00 70.98  ? 113 GLU A OE1 1 
ATOM   895   O OE2 . GLU A 1 113 ? -31.948 -13.124 -25.560 1.00 77.39  ? 113 GLU A OE2 1 
ATOM   896   N N   . PHE A 1 114 ? -26.329 -11.555 -26.280 1.00 40.63  ? 114 PHE A N   1 
ATOM   897   C CA  . PHE A 1 114 ? -24.964 -11.453 -25.817 1.00 45.19  ? 114 PHE A CA  1 
ATOM   898   C C   . PHE A 1 114 ? -24.812 -10.202 -24.956 1.00 56.05  ? 114 PHE A C   1 
ATOM   899   O O   . PHE A 1 114 ? -24.234 -10.234 -23.868 1.00 59.47  ? 114 PHE A O   1 
ATOM   900   C CB  . PHE A 1 114 ? -24.025 -11.472 -27.014 1.00 43.66  ? 114 PHE A CB  1 
ATOM   901   C CG  . PHE A 1 114 ? -23.853 -12.818 -27.684 1.00 47.83  ? 114 PHE A CG  1 
ATOM   902   C CD1 . PHE A 1 114 ? -24.372 -13.982 -27.142 1.00 48.56  ? 114 PHE A CD1 1 
ATOM   903   C CD2 . PHE A 1 114 ? -23.132 -12.929 -28.865 1.00 48.51  ? 114 PHE A CD2 1 
ATOM   904   C CE1 . PHE A 1 114 ? -24.218 -15.201 -27.792 1.00 49.20  ? 114 PHE A CE1 1 
ATOM   905   C CE2 . PHE A 1 114 ? -22.940 -14.160 -29.483 1.00 47.32  ? 114 PHE A CE2 1 
ATOM   906   C CZ  . PHE A 1 114 ? -23.491 -15.292 -28.951 1.00 44.51  ? 114 PHE A CZ  1 
ATOM   907   N N   . THR A 1 115 ? -25.407 -9.109  -25.418 1.00 54.01  ? 115 THR A N   1 
ATOM   908   C CA  . THR A 1 115 ? -25.254 -7.819  -24.773 1.00 59.06  ? 115 THR A CA  1 
ATOM   909   C C   . THR A 1 115 ? -25.910 -7.832  -23.394 1.00 49.57  ? 115 THR A C   1 
ATOM   910   O O   . THR A 1 115 ? -25.301 -7.393  -22.446 1.00 54.57  ? 115 THR A O   1 
ATOM   911   C CB  . THR A 1 115 ? -25.784 -6.723  -25.704 1.00 69.66  ? 115 THR A CB  1 
ATOM   912   O OG1 . THR A 1 115 ? -24.674 -6.439  -26.552 1.00 69.51  ? 115 THR A OG1 1 
ATOM   913   C CG2 . THR A 1 115 ? -26.268 -5.485  -24.979 1.00 79.84  ? 115 THR A CG2 1 
ATOM   914   N N   . LYS A 1 116 ? -27.144 -8.329  -23.281 1.00 52.18  ? 116 LYS A N   1 
ATOM   915   C CA  . LYS A 1 116 ? -27.798 -8.469  -21.989 1.00 54.50  ? 116 LYS A CA  1 
ATOM   916   C C   . LYS A 1 116 ? -26.907 -9.293  -21.044 1.00 54.17  ? 116 LYS A C   1 
ATOM   917   O O   . LYS A 1 116 ? -26.579 -8.824  -19.963 1.00 45.74  ? 116 LYS A O   1 
ATOM   918   C CB  . LYS A 1 116 ? -29.205 -9.048  -22.217 1.00 68.76  ? 116 LYS A CB  1 
ATOM   919   C CG  . LYS A 1 116 ? -29.914 -9.723  -21.034 1.00 79.18  ? 116 LYS A CG  1 
ATOM   920   C CD  . LYS A 1 116 ? -31.209 -10.453 -21.439 1.00 85.01  ? 116 LYS A CD  1 
ATOM   921   C CE  . LYS A 1 116 ? -32.029 -11.034 -20.297 1.00 99.29  ? 116 LYS A CE  1 
ATOM   922   N NZ  . LYS A 1 116 ? -31.551 -12.371 -19.849 1.00 97.32  ? 116 LYS A NZ  1 
ATOM   923   N N   . ARG A 1 117 ? -26.461 -10.492 -21.469 1.00 42.55  ? 117 ARG A N   1 
ATOM   924   C CA  . ARG A 1 117 ? -25.892 -11.471 -20.556 1.00 42.76  ? 117 ARG A CA  1 
ATOM   925   C C   . ARG A 1 117 ? -24.461 -11.091 -20.169 1.00 43.25  ? 117 ARG A C   1 
ATOM   926   O O   . ARG A 1 117 ? -23.915 -11.623 -19.202 1.00 43.23  ? 117 ARG A O   1 
ATOM   927   C CB  . ARG A 1 117 ? -25.943 -12.857 -21.195 1.00 42.07  ? 117 ARG A CB  1 
ATOM   928   C CG  . ARG A 1 117 ? -27.351 -13.422 -21.301 1.00 46.81  ? 117 ARG A CG  1 
ATOM   929   C CD  . ARG A 1 117 ? -27.432 -14.568 -22.306 1.00 48.68  ? 117 ARG A CD  1 
ATOM   930   N NE  . ARG A 1 117 ? -28.802 -14.977 -22.609 1.00 50.10  ? 117 ARG A NE  1 
ATOM   931   C CZ  . ARG A 1 117 ? -29.483 -15.943 -21.993 1.00 56.72  ? 117 ARG A CZ  1 
ATOM   932   N NH1 . ARG A 1 117 ? -28.933 -16.642 -21.019 1.00 51.77  ? 117 ARG A NH1 1 
ATOM   933   N NH2 . ARG A 1 117 ? -30.744 -16.176 -22.322 1.00 56.64  ? 117 ARG A NH2 1 
ATOM   934   N N   . MET A 1 118 ? -23.905 -10.145 -20.919 1.00 37.56  ? 118 MET A N   1 
ATOM   935   C CA  . MET A 1 118 ? -22.585 -9.580  -20.706 1.00 46.00  ? 118 MET A CA  1 
ATOM   936   C C   . MET A 1 118 ? -22.559 -8.747  -19.425 1.00 44.48  ? 118 MET A C   1 
ATOM   937   O O   . MET A 1 118 ? -21.491 -8.451  -18.902 1.00 41.80  ? 118 MET A O   1 
ATOM   938   C CB  . MET A 1 118 ? -22.255 -8.681  -21.903 1.00 49.29  ? 118 MET A CB  1 
ATOM   939   C CG  . MET A 1 118 ? -20.826 -8.264  -22.031 1.00 55.86  ? 118 MET A CG  1 
ATOM   940   S SD  . MET A 1 118 ? -20.445 -7.628  -23.717 1.00 55.91  ? 118 MET A SD  1 
ATOM   941   C CE  . MET A 1 118 ? -20.593 -9.099  -24.737 1.00 54.61  ? 118 MET A CE  1 
ATOM   942   N N   . GLN A 1 119 ? -23.737 -8.335  -18.945 1.00 40.48  ? 119 GLN A N   1 
ATOM   943   C CA  . GLN A 1 119 ? -23.836 -7.635  -17.669 1.00 46.83  ? 119 GLN A CA  1 
ATOM   944   C C   . GLN A 1 119 ? -23.831 -8.622  -16.506 1.00 40.74  ? 119 GLN A C   1 
ATOM   945   O O   . GLN A 1 119 ? -23.923 -8.210  -15.369 1.00 44.24  ? 119 GLN A O   1 
ATOM   946   C CB  . GLN A 1 119 ? -25.129 -6.821  -17.609 1.00 49.96  ? 119 GLN A CB  1 
ATOM   947   C CG  . GLN A 1 119 ? -25.241 -5.800  -18.731 1.00 49.90  ? 119 GLN A CG  1 
ATOM   948   C CD  . GLN A 1 119 ? -24.238 -4.691  -18.571 1.00 56.49  ? 119 GLN A CD  1 
ATOM   949   O OE1 . GLN A 1 119 ? -23.707 -4.462  -17.490 1.00 61.71  ? 119 GLN A OE1 1 
ATOM   950   N NE2 . GLN A 1 119 ? -24.003 -3.948  -19.635 1.00 59.89  ? 119 GLN A NE2 1 
ATOM   951   N N   . ASN A 1 120 ? -23.764 -9.922  -16.776 1.00 40.25  ? 120 ASN A N   1 
ATOM   952   C CA  . ASN A 1 120 ? -24.062 -10.926 -15.771 1.00 42.42  ? 120 ASN A CA  1 
ATOM   953   C C   . ASN A 1 120 ? -22.828 -11.748 -15.428 1.00 35.78  ? 120 ASN A C   1 
ATOM   954   O O   . ASN A 1 120 ? -22.947 -12.821 -14.885 1.00 41.37  ? 120 ASN A O   1 
ATOM   955   C CB  . ASN A 1 120 ? -25.220 -11.843 -16.195 1.00 47.10  ? 120 ASN A CB  1 
ATOM   956   C CG  . ASN A 1 120 ? -26.519 -11.085 -16.421 1.00 51.73  ? 120 ASN A CG  1 
ATOM   957   O OD1 . ASN A 1 120 ? -27.419 -11.553 -17.116 1.00 55.88  ? 120 ASN A OD1 1 
ATOM   958   N ND2 . ASN A 1 120 ? -26.607 -9.877  -15.902 1.00 51.76  ? 120 ASN A ND2 1 
ATOM   959   N N   . VAL A 1 121 ? -21.639 -11.196 -15.596 1.00 37.51  ? 121 VAL A N   1 
ATOM   960   C CA  . VAL A 1 121 ? -20.463 -11.864 -15.086 1.00 36.77  ? 121 VAL A CA  1 
ATOM   961   C C   . VAL A 1 121 ? -20.390 -11.656 -13.578 1.00 34.68  ? 121 VAL A C   1 
ATOM   962   O O   . VAL A 1 121 ? -20.273 -10.532 -13.093 1.00 33.44  ? 121 VAL A O   1 
ATOM   963   C CB  . VAL A 1 121 ? -19.196 -11.395 -15.802 1.00 33.22  ? 121 VAL A CB  1 
ATOM   964   C CG1 . VAL A 1 121 ? -18.000 -12.195 -15.341 1.00 35.72  ? 121 VAL A CG1 1 
ATOM   965   C CG2 . VAL A 1 121 ? -19.348 -11.521 -17.311 1.00 36.11  ? 121 VAL A CG2 1 
ATOM   966   N N   . PRO A 1 122 ? -20.402 -12.745 -12.789 1.00 32.34  ? 122 PRO A N   1 
ATOM   967   C CA  . PRO A 1 122 ? -20.385 -12.635 -11.335 1.00 36.46  ? 122 PRO A CA  1 
ATOM   968   C C   . PRO A 1 122 ? -19.194 -11.849 -10.823 1.00 35.88  ? 122 PRO A C   1 
ATOM   969   O O   . PRO A 1 122 ? -18.120 -11.898 -11.409 1.00 33.93  ? 122 PRO A O   1 
ATOM   970   C CB  . PRO A 1 122 ? -20.221 -14.091 -10.879 1.00 39.68  ? 122 PRO A CB  1 
ATOM   971   C CG  . PRO A 1 122 ? -20.827 -14.892 -12.031 1.00 32.37  ? 122 PRO A CG  1 
ATOM   972   C CD  . PRO A 1 122 ? -20.352 -14.136 -13.235 1.00 31.20  ? 122 PRO A CD  1 
ATOM   973   N N   . GLN A 1 123 ? -19.388 -11.184 -9.683  1.00 34.54  ? 123 GLN A N   1 
ATOM   974   C CA  . GLN A 1 123 ? -18.319 -10.459 -9.048  1.00 35.24  ? 123 GLN A CA  1 
ATOM   975   C C   . GLN A 1 123 ? -17.216 -11.446 -8.654  1.00 33.89  ? 123 GLN A C   1 
ATOM   976   O O   . GLN A 1 123 ? -16.052 -11.120 -8.820  1.00 32.61  ? 123 GLN A O   1 
ATOM   977   C CB  . GLN A 1 123 ? -18.889 -9.631  -7.907  1.00 43.08  ? 123 GLN A CB  1 
ATOM   978   C CG  . GLN A 1 123 ? -17.871 -8.832  -7.115  1.00 51.49  ? 123 GLN A CG  1 
ATOM   979   C CD  . GLN A 1 123 ? -17.175 -7.801  -7.960  1.00 57.62  ? 123 GLN A CD  1 
ATOM   980   O OE1 . GLN A 1 123 ? -17.810 -7.027  -8.673  1.00 57.87  ? 123 GLN A OE1 1 
ATOM   981   N NE2 . GLN A 1 123 ? -15.849 -7.827  -7.925  1.00 60.54  ? 123 GLN A NE2 1 
ATOM   982   N N   . TYR A 1 124 ? -17.545 -12.677 -8.222  1.00 32.74  ? 124 TYR A N   1 
ATOM   983   C CA  . TYR A 1 124 ? -16.500 -13.573 -7.744  1.00 32.14  ? 124 TYR A CA  1 
ATOM   984   C C   . TYR A 1 124 ? -15.583 -13.983 -8.900  1.00 33.26  ? 124 TYR A C   1 
ATOM   985   O O   . TYR A 1 124 ? -14.440 -14.311 -8.647  1.00 34.14  ? 124 TYR A O   1 
ATOM   986   C CB  . TYR A 1 124 ? -17.034 -14.781 -6.977  1.00 30.49  ? 124 TYR A CB  1 
ATOM   987   C CG  . TYR A 1 124 ? -17.803 -15.763 -7.824  1.00 30.99  ? 124 TYR A CG  1 
ATOM   988   C CD1 . TYR A 1 124 ? -17.166 -16.590 -8.728  1.00 32.21  ? 124 TYR A CD1 1 
ATOM   989   C CD2 . TYR A 1 124 ? -19.193 -15.788 -7.793  1.00 31.49  ? 124 TYR A CD2 1 
ATOM   990   C CE1 . TYR A 1 124 ? -17.888 -17.445 -9.557  1.00 33.23  ? 124 TYR A CE1 1 
ATOM   991   C CE2 . TYR A 1 124 ? -19.923 -16.637 -8.605  1.00 32.70  ? 124 TYR A CE2 1 
ATOM   992   C CZ  . TYR A 1 124 ? -19.273 -17.463 -9.501  1.00 32.81  ? 124 TYR A CZ  1 
ATOM   993   O OH  . TYR A 1 124 ? -20.031 -18.290 -10.322 1.00 36.80  ? 124 TYR A OH  1 
ATOM   994   N N   . VAL A 1 125 ? -15.997 -13.866 -10.168 1.00 31.30  ? 125 VAL A N   1 
ATOM   995   C CA  . VAL A 1 125 ? -15.074 -14.184 -11.274 1.00 31.67  ? 125 VAL A CA  1 
ATOM   996   C C   . VAL A 1 125 ? -13.923 -13.181 -11.307 1.00 31.20  ? 125 VAL A C   1 
ATOM   997   O O   . VAL A 1 125 ? -12.779 -13.573 -11.429 1.00 33.95  ? 125 VAL A O   1 
ATOM   998   C CB  . VAL A 1 125 ? -15.769 -14.228 -12.653 1.00 32.29  ? 125 VAL A CB  1 
ATOM   999   C CG1 . VAL A 1 125 ? -14.766 -14.244 -13.783 1.00 35.80  ? 125 VAL A CG1 1 
ATOM   1000  C CG2 . VAL A 1 125 ? -16.732 -15.385 -12.773 1.00 30.54  ? 125 VAL A CG2 1 
ATOM   1001  N N   . PHE A 1 126 ? -14.224 -11.883 -11.159 1.00 32.05  ? 126 PHE A N   1 
ATOM   1002  C CA  . PHE A 1 126 ? -13.215 -10.829 -11.014 1.00 33.52  ? 126 PHE A CA  1 
ATOM   1003  C C   . PHE A 1 126 ? -12.353 -11.008 -9.754  1.00 35.27  ? 126 PHE A C   1 
ATOM   1004  O O   . PHE A 1 126 ? -11.137 -10.803 -9.821  1.00 34.66  ? 126 PHE A O   1 
ATOM   1005  C CB  . PHE A 1 126 ? -13.882 -9.442  -11.054 1.00 33.10  ? 126 PHE A CB  1 
ATOM   1006  C CG  . PHE A 1 126 ? -14.740 -9.242  -12.278 1.00 33.65  ? 126 PHE A CG  1 
ATOM   1007  C CD1 . PHE A 1 126 ? -14.167 -9.079  -13.528 1.00 38.10  ? 126 PHE A CD1 1 
ATOM   1008  C CD2 . PHE A 1 126 ? -16.128 -9.293  -12.200 1.00 35.47  ? 126 PHE A CD2 1 
ATOM   1009  C CE1 . PHE A 1 126 ? -14.957 -8.907  -14.654 1.00 39.49  ? 126 PHE A CE1 1 
ATOM   1010  C CE2 . PHE A 1 126 ? -16.921 -9.119  -13.326 1.00 37.27  ? 126 PHE A CE2 1 
ATOM   1011  C CZ  . PHE A 1 126 ? -16.334 -8.960  -14.553 1.00 44.85  ? 126 PHE A CZ  1 
ATOM   1012  N N   . ASP A 1 127 ? -12.937 -11.398 -8.606  1.00 33.54  ? 127 ASP A N   1 
ATOM   1013  C CA  . ASP A 1 127 ? -12.121 -11.728 -7.434  1.00 32.75  ? 127 ASP A CA  1 
ATOM   1014  C C   . ASP A 1 127 ? -11.095 -12.800 -7.804  1.00 36.27  ? 127 ASP A C   1 
ATOM   1015  O O   . ASP A 1 127 ? -9.921  -12.686 -7.465  1.00 36.87  ? 127 ASP A O   1 
ATOM   1016  C CB  . ASP A 1 127 ? -12.959 -12.211 -6.235  1.00 33.05  ? 127 ASP A CB  1 
ATOM   1017  C CG  . ASP A 1 127 ? -14.004 -11.194 -5.773  1.00 42.27  ? 127 ASP A CG  1 
ATOM   1018  O OD1 . ASP A 1 127 ? -13.951 -10.046 -6.281  1.00 48.87  ? 127 ASP A OD1 1 
ATOM   1019  O OD2 . ASP A 1 127 ? -14.880 -11.536 -4.917  1.00 36.75  ? 127 ASP A OD2 1 
ATOM   1020  N N   . VAL A 1 128 ? -11.529 -13.871 -8.485  1.00 34.97  ? 128 VAL A N   1 
ATOM   1021  C CA  . VAL A 1 128 ? -10.591 -14.904 -8.885  1.00 36.31  ? 128 VAL A CA  1 
ATOM   1022  C C   . VAL A 1 128 ? -9.512  -14.323 -9.814  1.00 38.97  ? 128 VAL A C   1 
ATOM   1023  O O   . VAL A 1 128 ? -8.313  -14.515 -9.585  1.00 38.16  ? 128 VAL A O   1 
ATOM   1024  C CB  . VAL A 1 128 ? -11.319 -16.104 -9.513  1.00 33.46  ? 128 VAL A CB  1 
ATOM   1025  C CG1 . VAL A 1 128 ? -10.368 -16.982 -10.293 1.00 32.97  ? 128 VAL A CG1 1 
ATOM   1026  C CG2 . VAL A 1 128 ? -12.048 -16.936 -8.467  1.00 29.42  ? 128 VAL A CG2 1 
ATOM   1027  N N   . LEU A 1 129 ? -9.904  -13.550 -10.837 1.00 37.74  ? 129 LEU A N   1 
ATOM   1028  C CA  . LEU A 1 129 ? -8.910  -12.981 -11.737 1.00 34.99  ? 129 LEU A CA  1 
ATOM   1029  C C   . LEU A 1 129 ? -7.889  -12.154 -10.952 1.00 36.05  ? 129 LEU A C   1 
ATOM   1030  O O   . LEU A 1 129 ? -6.710  -12.246 -11.229 1.00 38.00  ? 129 LEU A O   1 
ATOM   1031  C CB  . LEU A 1 129 ? -9.596  -12.156 -12.827 1.00 34.46  ? 129 LEU A CB  1 
ATOM   1032  C CG  . LEU A 1 129 ? -10.403 -12.990 -13.822 1.00 37.54  ? 129 LEU A CG  1 
ATOM   1033  C CD1 . LEU A 1 129 ? -11.197 -12.117 -14.743 1.00 37.39  ? 129 LEU A CD1 1 
ATOM   1034  C CD2 . LEU A 1 129 ? -9.484  -13.875 -14.650 1.00 40.83  ? 129 LEU A CD2 1 
ATOM   1035  N N   . ARG A 1 130 ? -8.325  -11.367 -9.965  1.00 31.23  ? 130 ARG A N   1 
ATOM   1036  C CA  . ARG A 1 130 ? -7.441  -10.448 -9.282  1.00 34.16  ? 130 ARG A CA  1 
ATOM   1037  C C   . ARG A 1 130 ? -6.577  -11.195 -8.282  1.00 29.97  ? 130 ARG A C   1 
ATOM   1038  O O   . ARG A 1 130 ? -5.498  -10.731 -7.943  1.00 34.19  ? 130 ARG A O   1 
ATOM   1039  C CB  . ARG A 1 130 ? -8.167  -9.326  -8.518  1.00 38.77  ? 130 ARG A CB  1 
ATOM   1040  C CG  . ARG A 1 130 ? -8.748  -8.218  -9.390  1.00 42.69  ? 130 ARG A CG  1 
ATOM   1041  C CD  . ARG A 1 130 ? -9.184  -7.014  -8.557  1.00 39.14  ? 130 ARG A CD  1 
ATOM   1042  N NE  . ARG A 1 130 ? -8.061  -6.159  -8.263  1.00 37.09  ? 130 ARG A NE  1 
ATOM   1043  C CZ  . ARG A 1 130 ? -7.476  -5.362  -9.157  1.00 40.77  ? 130 ARG A CZ  1 
ATOM   1044  N NH1 . ARG A 1 130 ? -6.552  -4.502  -8.758  1.00 37.79  ? 130 ARG A NH1 1 
ATOM   1045  N NH2 . ARG A 1 130 ? -7.874  -5.366  -10.428 1.00 36.78  ? 130 ARG A NH2 1 
ATOM   1046  N N   . ALA A 1 131 ? -7.010  -12.351 -7.813  1.00 36.18  ? 131 ALA A N   1 
ATOM   1047  C CA  . ALA A 1 131 ? -6.145  -13.128 -6.914  1.00 38.57  ? 131 ALA A CA  1 
ATOM   1048  C C   . ALA A 1 131 ? -4.974  -13.816 -7.625  1.00 35.50  ? 131 ALA A C   1 
ATOM   1049  O O   . ALA A 1 131 ? -3.973  -14.162 -6.999  1.00 39.62  ? 131 ALA A O   1 
ATOM   1050  C CB  . ALA A 1 131 ? -6.958  -14.115 -6.152  1.00 34.43  ? 131 ALA A CB  1 
ATOM   1051  N N   . MET A 1 132 ? -5.049  -13.977 -8.937  1.00 37.50  ? 132 MET A N   1 
ATOM   1052  C CA  . MET A 1 132 ? -3.892  -14.446 -9.681  1.00 36.82  ? 132 MET A CA  1 
ATOM   1053  C C   . MET A 1 132 ? -2.862  -13.327 -9.814  1.00 39.64  ? 132 MET A C   1 
ATOM   1054  O O   . MET A 1 132 ? -3.207  -12.179 -10.103 1.00 42.05  ? 132 MET A O   1 
ATOM   1055  C CB  . MET A 1 132 ? -4.332  -14.927 -11.058 1.00 38.81  ? 132 MET A CB  1 
ATOM   1056  C CG  . MET A 1 132 ? -5.365  -16.024 -10.944 1.00 46.73  ? 132 MET A CG  1 
ATOM   1057  S SD  . MET A 1 132 ? -5.993  -16.599 -12.546 1.00 44.19  ? 132 MET A SD  1 
ATOM   1058  C CE  . MET A 1 132 ? -4.831  -17.940 -12.694 1.00 43.80  ? 132 MET A CE  1 
ATOM   1059  N N   . PRO A 1 133 ? -1.553  -13.602 -9.610  1.00 37.51  ? 133 PRO A N   1 
ATOM   1060  C CA  . PRO A 1 133 ? -0.531  -12.595 -9.825  1.00 31.30  ? 133 PRO A CA  1 
ATOM   1061  C C   . PRO A 1 133 ? -0.600  -12.076 -11.251 1.00 31.70  ? 133 PRO A C   1 
ATOM   1062  O O   . PRO A 1 133 ? -0.771  -12.856 -12.182 1.00 34.65  ? 133 PRO A O   1 
ATOM   1063  C CB  . PRO A 1 133 ? 0.778   -13.336 -9.608  1.00 36.90  ? 133 PRO A CB  1 
ATOM   1064  C CG  . PRO A 1 133 ? 0.401   -14.538 -8.809  1.00 38.64  ? 133 PRO A CG  1 
ATOM   1065  C CD  . PRO A 1 133 ? -0.980  -14.905 -9.291  1.00 34.61  ? 133 PRO A CD  1 
ATOM   1066  N N   . VAL A 1 134 ? -0.499  -10.751 -11.396 1.00 29.62  ? 134 VAL A N   1 
ATOM   1067  C CA  . VAL A 1 134 ? -0.697  -10.075 -12.650 1.00 32.32  ? 134 VAL A CA  1 
ATOM   1068  C C   . VAL A 1 134 ? 0.295   -10.560 -13.743 1.00 34.09  ? 134 VAL A C   1 
ATOM   1069  O O   . VAL A 1 134 ? 0.071   -10.307 -14.920 1.00 35.52  ? 134 VAL A O   1 
ATOM   1070  C CB  . VAL A 1 134 ? -0.549  -8.559  -12.411 1.00 37.55  ? 134 VAL A CB  1 
ATOM   1071  C CG1 . VAL A 1 134 ? 0.906   -8.170  -12.142 1.00 35.51  ? 134 VAL A CG1 1 
ATOM   1072  C CG2 . VAL A 1 134 ? -1.077  -7.739  -13.595 1.00 39.02  ? 134 VAL A CG2 1 
ATOM   1073  N N   . ASP A 1 135 ? 1.414   -11.201 -13.384 1.00 31.92  ? 135 ASP A N   1 
ATOM   1074  C CA  . ASP A 1 135 ? 2.398   -11.685 -14.349 1.00 36.72  ? 135 ASP A CA  1 
ATOM   1075  C C   . ASP A 1 135 ? 2.059   -13.113 -14.788 1.00 36.46  ? 135 ASP A C   1 
ATOM   1076  O O   . ASP A 1 135 ? 2.811   -13.707 -15.512 1.00 40.08  ? 135 ASP A O   1 
ATOM   1077  C CB  . ASP A 1 135 ? 3.851   -11.650 -13.818 1.00 34.76  ? 135 ASP A CB  1 
ATOM   1078  C CG  . ASP A 1 135 ? 4.062   -12.502 -12.581 1.00 38.77  ? 135 ASP A CG  1 
ATOM   1079  O OD1 . ASP A 1 135 ? 3.020   -12.999 -12.073 1.00 40.06  ? 135 ASP A OD1 1 
ATOM   1080  O OD2 . ASP A 1 135 ? 5.258   -12.684 -12.123 1.00 38.44  ? 135 ASP A OD2 1 
ATOM   1081  N N   . THR A 1 136 ? 0.934   -13.675 -14.342 1.00 38.85  ? 136 THR A N   1 
ATOM   1082  C CA  . THR A 1 136 ? 0.475   -14.958 -14.820 1.00 36.37  ? 136 THR A CA  1 
ATOM   1083  C C   . THR A 1 136 ? 0.182   -14.865 -16.319 1.00 43.31  ? 136 THR A C   1 
ATOM   1084  O O   . THR A 1 136 ? -0.256  -13.829 -16.812 1.00 41.18  ? 136 THR A O   1 
ATOM   1085  C CB  . THR A 1 136 ? -0.768  -15.390 -14.030 1.00 37.59  ? 136 THR A CB  1 
ATOM   1086  O OG1 . THR A 1 136 ? -0.460  -15.523 -12.638 1.00 34.03  ? 136 THR A OG1 1 
ATOM   1087  C CG2 . THR A 1 136 ? -1.354  -16.680 -14.571 1.00 36.07  ? 136 THR A CG2 1 
ATOM   1088  N N   . HIS A 1 137 ? 0.427   -15.956 -17.052 1.00 38.97  ? 137 HIS A N   1 
ATOM   1089  C CA  . HIS A 1 137 ? 0.219   -15.950 -18.490 1.00 38.05  ? 137 HIS A CA  1 
ATOM   1090  C C   . HIS A 1 137 ? -1.254  -15.667 -18.769 1.00 35.15  ? 137 HIS A C   1 
ATOM   1091  O O   . HIS A 1 137 ? -2.124  -16.202 -18.096 1.00 35.66  ? 137 HIS A O   1 
ATOM   1092  C CB  . HIS A 1 137 ? 0.666   -17.288 -19.108 1.00 42.57  ? 137 HIS A CB  1 
ATOM   1093  C CG  . HIS A 1 137 ? 0.664   -17.268 -20.598 1.00 36.55  ? 137 HIS A CG  1 
ATOM   1094  N ND1 . HIS A 1 137 ? -0.506  -17.244 -21.326 1.00 35.50  ? 137 HIS A ND1 1 
ATOM   1095  C CD2 . HIS A 1 137 ? 1.674   -17.187 -21.487 1.00 34.39  ? 137 HIS A CD2 1 
ATOM   1096  C CE1 . HIS A 1 137 ? -0.201  -17.153 -22.620 1.00 37.50  ? 137 HIS A CE1 1 
ATOM   1097  N NE2 . HIS A 1 137 ? 1.107   -17.064 -22.737 1.00 35.46  ? 137 HIS A NE2 1 
ATOM   1098  N N   . PRO A 1 138 ? -1.594  -14.795 -19.733 1.00 30.93  ? 138 PRO A N   1 
ATOM   1099  C CA  . PRO A 1 138 ? -2.987  -14.446 -19.987 1.00 30.60  ? 138 PRO A CA  1 
ATOM   1100  C C   . PRO A 1 138 ? -3.909  -15.635 -20.265 1.00 32.52  ? 138 PRO A C   1 
ATOM   1101  O O   . PRO A 1 138 ? -5.085  -15.611 -19.895 1.00 33.10  ? 138 PRO A O   1 
ATOM   1102  C CB  . PRO A 1 138 ? -2.942  -13.451 -21.158 1.00 34.08  ? 138 PRO A CB  1 
ATOM   1103  C CG  . PRO A 1 138 ? -1.529  -13.582 -21.724 1.00 39.52  ? 138 PRO A CG  1 
ATOM   1104  C CD  . PRO A 1 138 ? -0.657  -14.033 -20.566 1.00 35.87  ? 138 PRO A CD  1 
ATOM   1105  N N   . MET A 1 139 ? -3.383  -16.696 -20.880 1.00 31.81  ? 139 MET A N   1 
ATOM   1106  C CA  . MET A 1 139 ? -4.216  -17.835 -21.232 1.00 31.06  ? 139 MET A CA  1 
ATOM   1107  C C   . MET A 1 139 ? -4.510  -18.677 -19.997 1.00 32.02  ? 139 MET A C   1 
ATOM   1108  O O   . MET A 1 139 ? -5.480  -19.380 -19.964 1.00 34.03  ? 139 MET A O   1 
ATOM   1109  C CB  . MET A 1 139 ? -3.533  -18.692 -22.301 1.00 34.16  ? 139 MET A CB  1 
ATOM   1110  C CG  . MET A 1 139 ? -3.742  -18.180 -23.722 1.00 32.49  ? 139 MET A CG  1 
ATOM   1111  S SD  . MET A 1 139 ? -5.501  -18.242 -24.230 1.00 37.25  ? 139 MET A SD  1 
ATOM   1112  C CE  . MET A 1 139 ? -5.910  -19.973 -24.060 1.00 35.40  ? 139 MET A CE  1 
ATOM   1113  N N   . THR A 1 140 ? -3.685  -18.599 -18.958 1.00 34.89  ? 140 THR A N   1 
ATOM   1114  C CA  . THR A 1 140 ? -3.979  -19.255 -17.698 1.00 31.54  ? 140 THR A CA  1 
ATOM   1115  C C   . THR A 1 140 ? -5.082  -18.525 -16.948 1.00 31.58  ? 140 THR A C   1 
ATOM   1116  O O   . THR A 1 140 ? -5.966  -19.138 -16.384 1.00 33.87  ? 140 THR A O   1 
ATOM   1117  C CB  . THR A 1 140 ? -2.737  -19.216 -16.818 1.00 30.43  ? 140 THR A CB  1 
ATOM   1118  O OG1 . THR A 1 140 ? -1.769  -19.926 -17.571 1.00 31.03  ? 140 THR A OG1 1 
ATOM   1119  C CG2 . THR A 1 140 ? -2.949  -19.820 -15.451 1.00 33.83  ? 140 THR A CG2 1 
ATOM   1120  N N   . MET A 1 141 ? -4.990  -17.186 -16.938 1.00 33.56  ? 141 MET A N   1 
ATOM   1121  C CA  . MET A 1 141 ? -5.998  -16.326 -16.350 1.00 32.27  ? 141 MET A CA  1 
ATOM   1122  C C   . MET A 1 141 ? -7.350  -16.557 -17.044 1.00 35.31  ? 141 MET A C   1 
ATOM   1123  O O   . MET A 1 141 ? -8.385  -16.628 -16.383 1.00 34.73  ? 141 MET A O   1 
ATOM   1124  C CB  . MET A 1 141 ? -5.598  -14.853 -16.541 1.00 31.82  ? 141 MET A CB  1 
ATOM   1125  C CG  . MET A 1 141 ? -4.539  -14.337 -15.594 1.00 29.51  ? 141 MET A CG  1 
ATOM   1126  S SD  . MET A 1 141 ? -4.250  -12.579 -15.907 1.00 39.00  ? 141 MET A SD  1 
ATOM   1127  C CE  . MET A 1 141 ? -2.892  -12.229 -14.798 1.00 41.21  ? 141 MET A CE  1 
ATOM   1128  N N   . PHE A 1 142 ? -7.352  -16.609 -18.383 1.00 29.99  ? 142 PHE A N   1 
ATOM   1129  C CA  . PHE A 1 142 ? -8.582  -16.789 -19.150 1.00 34.63  ? 142 PHE A CA  1 
ATOM   1130  C C   . PHE A 1 142 ? -9.284  -18.099 -18.804 1.00 37.30  ? 142 PHE A C   1 
ATOM   1131  O O   . PHE A 1 142 ? -10.506 -18.145 -18.492 1.00 35.56  ? 142 PHE A O   1 
ATOM   1132  C CB  . PHE A 1 142 ? -8.267  -16.750 -20.644 1.00 35.05  ? 142 PHE A CB  1 
ATOM   1133  C CG  . PHE A 1 142 ? -9.428  -16.670 -21.603 1.00 34.31  ? 142 PHE A CG  1 
ATOM   1134  C CD1 . PHE A 1 142 ? -10.376 -15.677 -21.501 1.00 34.79  ? 142 PHE A CD1 1 
ATOM   1135  C CD2 . PHE A 1 142 ? -9.501  -17.543 -22.672 1.00 41.78  ? 142 PHE A CD2 1 
ATOM   1136  C CE1 . PHE A 1 142 ? -11.391 -15.565 -22.435 1.00 41.30  ? 142 PHE A CE1 1 
ATOM   1137  C CE2 . PHE A 1 142 ? -10.524 -17.449 -23.603 1.00 44.55  ? 142 PHE A CE2 1 
ATOM   1138  C CZ  . PHE A 1 142 ? -11.470 -16.456 -23.484 1.00 44.71  ? 142 PHE A CZ  1 
ATOM   1139  N N   . ALA A 1 143 ? -8.492  -19.175 -18.856 1.00 36.07  ? 143 ALA A N   1 
ATOM   1140  C CA  . ALA A 1 143 ? -9.046  -20.485 -18.547 1.00 34.20  ? 143 ALA A CA  1 
ATOM   1141  C C   . ALA A 1 143 ? -9.630  -20.485 -17.138 1.00 34.81  ? 143 ALA A C   1 
ATOM   1142  O O   . ALA A 1 143 ? -10.709 -21.010 -16.906 1.00 40.49  ? 143 ALA A O   1 
ATOM   1143  C CB  . ALA A 1 143 ? -7.988  -21.528 -18.702 1.00 32.07  ? 143 ALA A CB  1 
ATOM   1144  N N   . ALA A 1 144 ? -8.919  -19.862 -16.197 1.00 39.40  ? 144 ALA A N   1 
ATOM   1145  C CA  . ALA A 1 144 ? -9.302  -19.902 -14.791 1.00 38.28  ? 144 ALA A CA  1 
ATOM   1146  C C   . ALA A 1 144 ? -10.571 -19.101 -14.561 1.00 37.06  ? 144 ALA A C   1 
ATOM   1147  O O   . ALA A 1 144 ? -11.405 -19.503 -13.759 1.00 32.94  ? 144 ALA A O   1 
ATOM   1148  C CB  . ALA A 1 144 ? -8.186  -19.352 -13.925 1.00 43.65  ? 144 ALA A CB  1 
ATOM   1149  N N   . GLY A 1 145 ? -10.728 -17.978 -15.274 1.00 36.66  ? 145 GLY A N   1 
ATOM   1150  C CA  . GLY A 1 145 ? -11.914 -17.165 -15.076 1.00 33.27  ? 145 GLY A CA  1 
ATOM   1151  C C   . GLY A 1 145 ? -13.166 -17.856 -15.592 1.00 35.22  ? 145 GLY A C   1 
ATOM   1152  O O   . GLY A 1 145 ? -14.205 -17.834 -14.928 1.00 35.74  ? 145 GLY A O   1 
ATOM   1153  N N   . ILE A 1 146 ? -13.023 -18.501 -16.758 1.00 36.50  ? 146 ILE A N   1 
ATOM   1154  C CA  . ILE A 1 146 ? -14.082 -19.300 -17.349 1.00 33.14  ? 146 ILE A CA  1 
ATOM   1155  C C   . ILE A 1 146 ? -14.453 -20.420 -16.380 1.00 34.28  ? 146 ILE A C   1 
ATOM   1156  O O   . ILE A 1 146 ? -15.635 -20.626 -16.066 1.00 35.38  ? 146 ILE A O   1 
ATOM   1157  C CB  . ILE A 1 146 ? -13.614 -19.881 -18.696 1.00 33.21  ? 146 ILE A CB  1 
ATOM   1158  C CG1 . ILE A 1 146 ? -13.370 -18.784 -19.730 1.00 35.32  ? 146 ILE A CG1 1 
ATOM   1159  C CG2 . ILE A 1 146 ? -14.607 -20.901 -19.184 1.00 33.31  ? 146 ILE A CG2 1 
ATOM   1160  C CD1 . ILE A 1 146 ? -12.455 -19.213 -20.877 1.00 38.27  ? 146 ILE A CD1 1 
ATOM   1161  N N   . LEU A 1 147 ? -13.434 -21.132 -15.885 1.00 31.42  ? 147 LEU A N   1 
ATOM   1162  C CA  . LEU A 1 147 ? -13.696 -22.265 -15.008 1.00 30.04  ? 147 LEU A CA  1 
ATOM   1163  C C   . LEU A 1 147 ? -14.404 -21.821 -13.726 1.00 32.05  ? 147 LEU A C   1 
ATOM   1164  O O   . LEU A 1 147 ? -15.317 -22.490 -13.293 1.00 36.17  ? 147 LEU A O   1 
ATOM   1165  C CB  . LEU A 1 147 ? -12.389 -22.981 -14.715 1.00 30.50  ? 147 LEU A CB  1 
ATOM   1166  C CG  . LEU A 1 147 ? -12.486 -24.164 -13.749 1.00 35.00  ? 147 LEU A CG  1 
ATOM   1167  C CD1 . LEU A 1 147 ? -13.522 -25.175 -14.173 1.00 34.37  ? 147 LEU A CD1 1 
ATOM   1168  C CD2 . LEU A 1 147 ? -11.150 -24.827 -13.592 1.00 32.36  ? 147 LEU A CD2 1 
ATOM   1169  N N   . ALA A 1 148 ? -14.072 -20.650 -13.148 1.00 32.73  ? 148 ALA A N   1 
ATOM   1170  C CA  . ALA A 1 148 ? -14.697 -20.216 -11.904 1.00 33.13  ? 148 ALA A CA  1 
ATOM   1171  C C   . ALA A 1 148 ? -16.218 -20.077 -12.075 1.00 37.33  ? 148 ALA A C   1 
ATOM   1172  O O   . ALA A 1 148 ? -17.014 -20.237 -11.155 1.00 35.69  ? 148 ALA A O   1 
ATOM   1173  C CB  . ALA A 1 148 ? -14.076 -18.897 -11.481 1.00 35.43  ? 148 ALA A CB  1 
ATOM   1174  N N   . MET A 1 149 ? -16.627 -19.759 -13.292 1.00 32.22  ? 149 MET A N   1 
ATOM   1175  C CA  . MET A 1 149 ? -17.996 -19.427 -13.563 1.00 35.43  ? 149 MET A CA  1 
ATOM   1176  C C   . MET A 1 149 ? -18.786 -20.700 -13.803 1.00 33.51  ? 149 MET A C   1 
ATOM   1177  O O   . MET A 1 149 ? -19.984 -20.629 -13.976 1.00 36.90  ? 149 MET A O   1 
ATOM   1178  C CB  . MET A 1 149 ? -18.011 -18.472 -14.750 1.00 40.57  ? 149 MET A CB  1 
ATOM   1179  C CG  . MET A 1 149 ? -19.323 -17.867 -15.062 1.00 39.03  ? 149 MET A CG  1 
ATOM   1180  S SD  . MET A 1 149 ? -19.114 -16.533 -16.327 1.00 38.88  ? 149 MET A SD  1 
ATOM   1181  C CE  . MET A 1 149 ? -20.881 -16.279 -16.563 1.00 35.53  ? 149 MET A CE  1 
ATOM   1182  N N   . GLN A 1 150 ? -18.141 -21.865 -13.590 1.00 38.00  ? 150 GLN A N   1 
ATOM   1183  C CA  . GLN A 1 150 ? -18.814 -23.152 -13.620 1.00 32.44  ? 150 GLN A CA  1 
ATOM   1184  C C   . GLN A 1 150 ? -19.914 -23.238 -12.566 1.00 33.67  ? 150 GLN A C   1 
ATOM   1185  O O   . GLN A 1 150 ? -20.938 -23.892 -12.795 1.00 40.32  ? 150 GLN A O   1 
ATOM   1186  C CB  . GLN A 1 150 ? -17.819 -24.297 -13.466 1.00 33.28  ? 150 GLN A CB  1 
ATOM   1187  C CG  . GLN A 1 150 ? -18.438 -25.689 -13.570 1.00 34.81  ? 150 GLN A CG  1 
ATOM   1188  C CD  . GLN A 1 150 ? -19.083 -26.251 -12.319 1.00 41.20  ? 150 GLN A CD  1 
ATOM   1189  O OE1 . GLN A 1 150 ? -18.791 -25.860 -11.190 1.00 38.72  ? 150 GLN A OE1 1 
ATOM   1190  N NE2 . GLN A 1 150 ? -19.944 -27.239 -12.512 1.00 39.46  ? 150 GLN A NE2 1 
ATOM   1191  N N   . ARG A 1 151 ? -19.743 -22.548 -11.436 1.00 36.46  ? 151 ARG A N   1 
ATOM   1192  C CA  . ARG A 1 151 ? -20.756 -22.487 -10.380 1.00 35.32  ? 151 ARG A CA  1 
ATOM   1193  C C   . ARG A 1 151 ? -22.113 -22.027 -10.922 1.00 37.81  ? 151 ARG A C   1 
ATOM   1194  O O   . ARG A 1 151 ? -23.121 -22.385 -10.349 1.00 33.52  ? 151 ARG A O   1 
ATOM   1195  C CB  . ARG A 1 151 ? -20.294 -21.529 -9.276  1.00 38.94  ? 151 ARG A CB  1 
ATOM   1196  C CG  . ARG A 1 151 ? -21.255 -21.390 -8.108  1.00 41.61  ? 151 ARG A CG  1 
ATOM   1197  C CD  . ARG A 1 151 ? -20.920 -20.158 -7.301  1.00 46.40  ? 151 ARG A CD  1 
ATOM   1198  N NE  . ARG A 1 151 ? -21.868 -19.993 -6.200  1.00 48.34  ? 151 ARG A NE  1 
ATOM   1199  C CZ  . ARG A 1 151 ? -22.893 -19.143 -6.197  1.00 45.49  ? 151 ARG A CZ  1 
ATOM   1200  N NH1 . ARG A 1 151 ? -23.113 -18.347 -7.236  1.00 41.17  ? 151 ARG A NH1 1 
ATOM   1201  N NH2 . ARG A 1 151 ? -23.716 -19.127 -5.168  1.00 41.33  ? 151 ARG A NH2 1 
ATOM   1202  N N   . GLU A 1 152 ? -22.154 -21.208 -11.995 1.00 39.75  ? 152 GLU A N   1 
ATOM   1203  C CA  . GLU A 1 152 ? -23.421 -20.766 -12.563 1.00 39.97  ? 152 GLU A CA  1 
ATOM   1204  C C   . GLU A 1 152 ? -23.911 -21.708 -13.667 1.00 37.93  ? 152 GLU A C   1 
ATOM   1205  O O   . GLU A 1 152 ? -24.756 -21.310 -14.454 1.00 40.41  ? 152 GLU A O   1 
ATOM   1206  C CB  . GLU A 1 152 ? -23.301 -19.381 -13.211 1.00 42.70  ? 152 GLU A CB  1 
ATOM   1207  C CG  . GLU A 1 152 ? -22.762 -18.293 -12.293 1.00 45.06  ? 152 GLU A CG  1 
ATOM   1208  C CD  . GLU A 1 152 ? -23.292 -18.338 -10.865 1.00 45.64  ? 152 GLU A CD  1 
ATOM   1209  O OE1 . GLU A 1 152 ? -22.459 -18.421 -9.951  1.00 42.66  ? 152 GLU A OE1 1 
ATOM   1210  O OE2 . GLU A 1 152 ? -24.546 -18.340 -10.673 1.00 46.51  ? 152 GLU A OE2 1 
ATOM   1211  N N   . SER A 1 153 ? -23.418 -22.952 -13.736 1.00 46.60  ? 153 SER A N   1 
ATOM   1212  C CA  . SER A 1 153 ? -23.802 -23.845 -14.828 1.00 42.90  ? 153 SER A CA  1 
ATOM   1213  C C   . SER A 1 153 ? -25.235 -24.325 -14.644 1.00 46.40  ? 153 SER A C   1 
ATOM   1214  O O   . SER A 1 153 ? -25.559 -25.029 -13.701 1.00 42.00  ? 153 SER A O   1 
ATOM   1215  C CB  . SER A 1 153 ? -22.910 -25.038 -14.978 1.00 40.40  ? 153 SER A CB  1 
ATOM   1216  O OG  . SER A 1 153 ? -23.402 -25.894 -16.006 1.00 39.16  ? 153 SER A OG  1 
ATOM   1217  N N   . VAL A 1 154 ? -26.059 -24.015 -15.637 1.00 44.30  ? 154 VAL A N   1 
ATOM   1218  C CA  . VAL A 1 154 ? -27.418 -24.508 -15.687 1.00 46.33  ? 154 VAL A CA  1 
ATOM   1219  C C   . VAL A 1 154 ? -27.422 -26.013 -15.952 1.00 44.92  ? 154 VAL A C   1 
ATOM   1220  O O   . VAL A 1 154 ? -28.195 -26.755 -15.355 1.00 43.48  ? 154 VAL A O   1 
ATOM   1221  C CB  . VAL A 1 154 ? -28.168 -23.687 -16.751 1.00 46.68  ? 154 VAL A CB  1 
ATOM   1222  C CG1 . VAL A 1 154 ? -29.456 -24.339 -17.221 1.00 45.91  ? 154 VAL A CG1 1 
ATOM   1223  C CG2 . VAL A 1 154 ? -28.404 -22.284 -16.207 1.00 47.68  ? 154 VAL A CG2 1 
ATOM   1224  N N   . PHE A 1 155 ? -26.550 -26.464 -16.853 1.00 46.96  ? 155 PHE A N   1 
ATOM   1225  C CA  . PHE A 1 155 ? -26.525 -27.868 -17.209 1.00 43.37  ? 155 PHE A CA  1 
ATOM   1226  C C   . PHE A 1 155 ? -26.137 -28.726 -16.010 1.00 43.36  ? 155 PHE A C   1 
ATOM   1227  O O   . PHE A 1 155 ? -26.748 -29.755 -15.812 1.00 45.61  ? 155 PHE A O   1 
ATOM   1228  C CB  . PHE A 1 155 ? -25.545 -28.132 -18.344 1.00 39.16  ? 155 PHE A CB  1 
ATOM   1229  C CG  . PHE A 1 155 ? -25.455 -29.582 -18.736 1.00 42.77  ? 155 PHE A CG  1 
ATOM   1230  C CD1 . PHE A 1 155 ? -24.726 -30.486 -17.983 1.00 48.36  ? 155 PHE A CD1 1 
ATOM   1231  C CD2 . PHE A 1 155 ? -26.129 -30.052 -19.853 1.00 45.85  ? 155 PHE A CD2 1 
ATOM   1232  C CE1 . PHE A 1 155 ? -24.639 -31.818 -18.369 1.00 51.04  ? 155 PHE A CE1 1 
ATOM   1233  C CE2 . PHE A 1 155 ? -26.057 -31.386 -20.227 1.00 43.17  ? 155 PHE A CE2 1 
ATOM   1234  C CZ  . PHE A 1 155 ? -25.296 -32.261 -19.502 1.00 44.87  ? 155 PHE A CZ  1 
ATOM   1235  N N   . ALA A 1 156 ? -25.076 -28.349 -15.277 1.00 41.84  ? 156 ALA A N   1 
ATOM   1236  C CA  . ALA A 1 156 ? -24.674 -29.124 -14.116 1.00 46.20  ? 156 ALA A CA  1 
ATOM   1237  C C   . ALA A 1 156 ? -25.808 -29.160 -13.102 1.00 41.75  ? 156 ALA A C   1 
ATOM   1238  O O   . ALA A 1 156 ? -25.988 -30.168 -12.442 1.00 48.30  ? 156 ALA A O   1 
ATOM   1239  C CB  . ALA A 1 156 ? -23.416 -28.609 -13.458 1.00 40.10  ? 156 ALA A CB  1 
ATOM   1240  N N   . LYS A 1 157 ? -26.541 -28.064 -12.966 1.00 45.06  ? 157 LYS A N   1 
ATOM   1241  C CA  . LYS A 1 157 ? -27.580 -28.009 -11.957 1.00 53.89  ? 157 LYS A CA  1 
ATOM   1242  C C   . LYS A 1 157 ? -28.755 -28.880 -12.388 1.00 54.71  ? 157 LYS A C   1 
ATOM   1243  O O   . LYS A 1 157 ? -29.321 -29.589 -11.557 1.00 46.01  ? 157 LYS A O   1 
ATOM   1244  C CB  . LYS A 1 157 ? -28.029 -26.566 -11.723 1.00 56.59  ? 157 LYS A CB  1 
ATOM   1245  C CG  . LYS A 1 157 ? -29.077 -26.431 -10.635 1.00 71.22  ? 157 LYS A CG  1 
ATOM   1246  C CD  . LYS A 1 157 ? -29.136 -25.051 -10.026 1.00 89.13  ? 157 LYS A CD  1 
ATOM   1247  C CE  . LYS A 1 157 ? -29.991 -24.996 -8.777  1.00 94.20  ? 157 LYS A CE  1 
ATOM   1248  N NZ  . LYS A 1 157 ? -29.908 -23.673 -8.118  1.00 97.81  ? 157 LYS A NZ  1 
ATOM   1249  N N   . ARG A 1 158 ? -29.132 -28.805 -13.681 1.00 51.83  ? 158 ARG A N   1 
ATOM   1250  C CA  . ARG A 1 158 ? -30.311 -29.524 -14.147 1.00 50.48  ? 158 ARG A CA  1 
ATOM   1251  C C   . ARG A 1 158 ? -29.993 -31.012 -14.172 1.00 46.09  ? 158 ARG A C   1 
ATOM   1252  O O   . ARG A 1 158 ? -30.847 -31.822 -13.839 1.00 50.53  ? 158 ARG A O   1 
ATOM   1253  C CB  . ARG A 1 158 ? -30.882 -28.947 -15.448 1.00 54.06  ? 158 ARG A CB  1 
ATOM   1254  C CG  . ARG A 1 158 ? -32.175 -28.161 -15.232 1.00 67.91  ? 158 ARG A CG  1 
ATOM   1255  C CD  . ARG A 1 158 ? -32.266 -26.804 -15.920 1.00 80.77  ? 158 ARG A CD  1 
ATOM   1256  N NE  . ARG A 1 158 ? -32.470 -26.788 -17.378 1.00 93.62  ? 158 ARG A NE  1 
ATOM   1257  C CZ  . ARG A 1 158 ? -32.795 -25.697 -18.087 1.00 80.83  ? 158 ARG A CZ  1 
ATOM   1258  N NH1 . ARG A 1 158 ? -32.846 -25.748 -19.407 1.00 67.27  ? 158 ARG A NH1 1 
ATOM   1259  N NH2 . ARG A 1 158 ? -33.047 -24.548 -17.471 1.00 74.35  ? 158 ARG A NH2 1 
ATOM   1260  N N   . TYR A 1 159 ? -28.730 -31.363 -14.414 1.00 46.36  ? 159 TYR A N   1 
ATOM   1261  C CA  . TYR A 1 159 ? -28.325 -32.756 -14.339 1.00 52.40  ? 159 TYR A CA  1 
ATOM   1262  C C   . TYR A 1 159 ? -28.438 -33.325 -12.915 1.00 53.50  ? 159 TYR A C   1 
ATOM   1263  O O   . TYR A 1 159 ? -28.793 -34.484 -12.755 1.00 47.43  ? 159 TYR A O   1 
ATOM   1264  C CB  . TYR A 1 159 ? -26.897 -32.951 -14.851 1.00 50.50  ? 159 TYR A CB  1 
ATOM   1265  C CG  . TYR A 1 159 ? -26.567 -34.415 -14.993 1.00 51.50  ? 159 TYR A CG  1 
ATOM   1266  C CD1 . TYR A 1 159 ? -26.868 -35.109 -16.152 1.00 48.67  ? 159 TYR A CD1 1 
ATOM   1267  C CD2 . TYR A 1 159 ? -26.058 -35.124 -13.918 1.00 52.86  ? 159 TYR A CD2 1 
ATOM   1268  C CE1 . TYR A 1 159 ? -26.621 -36.467 -16.261 1.00 53.60  ? 159 TYR A CE1 1 
ATOM   1269  C CE2 . TYR A 1 159 ? -25.821 -36.480 -14.007 1.00 58.17  ? 159 TYR A CE2 1 
ATOM   1270  C CZ  . TYR A 1 159 ? -26.105 -37.156 -15.179 1.00 54.62  ? 159 TYR A CZ  1 
ATOM   1271  O OH  . TYR A 1 159 ? -25.849 -38.510 -15.234 1.00 54.44  ? 159 TYR A OH  1 
ATOM   1272  N N   . GLU A 1 160 ? -28.070 -32.547 -11.889 1.00 59.37  ? 160 GLU A N   1 
ATOM   1273  C CA  . GLU A 1 160 ? -28.171 -32.988 -10.500 1.00 68.03  ? 160 GLU A CA  1 
ATOM   1274  C C   . GLU A 1 160 ? -29.629 -33.210 -10.105 1.00 56.97  ? 160 GLU A C   1 
ATOM   1275  O O   . GLU A 1 160 ? -29.920 -34.120 -9.348  1.00 53.24  ? 160 GLU A O   1 
ATOM   1276  C CB  . GLU A 1 160 ? -27.570 -31.984 -9.506  1.00 73.51  ? 160 GLU A CB  1 
ATOM   1277  C CG  . GLU A 1 160 ? -26.057 -32.022 -9.427  1.00 85.62  ? 160 GLU A CG  1 
ATOM   1278  C CD  . GLU A 1 160 ? -25.477 -33.115 -8.543  1.00 100.70 ? 160 GLU A CD  1 
ATOM   1279  O OE1 . GLU A 1 160 ? -25.831 -34.297 -8.751  1.00 88.61  ? 160 GLU A OE1 1 
ATOM   1280  O OE2 . GLU A 1 160 ? -24.649 -32.780 -7.655  1.00 109.28 ? 160 GLU A OE2 1 
ATOM   1281  N N   . GLU A 1 161 ? -30.529 -32.356 -10.592 1.00 56.29  ? 161 GLU A N   1 
ATOM   1282  C CA  . GLU A 1 161 ? -31.931 -32.406 -10.217 1.00 61.87  ? 161 GLU A CA  1 
ATOM   1283  C C   . GLU A 1 161 ? -32.670 -33.535 -10.930 1.00 64.31  ? 161 GLU A C   1 
ATOM   1284  O O   . GLU A 1 161 ? -33.827 -33.772 -10.605 1.00 74.11  ? 161 GLU A O   1 
ATOM   1285  C CB  . GLU A 1 161 ? -32.646 -31.108 -10.603 1.00 69.40  ? 161 GLU A CB  1 
ATOM   1286  C CG  . GLU A 1 161 ? -32.225 -29.886 -9.799  1.00 77.77  ? 161 GLU A CG  1 
ATOM   1287  C CD  . GLU A 1 161 ? -32.737 -28.556 -10.341 1.00 84.13  ? 161 GLU A CD  1 
ATOM   1288  O OE1 . GLU A 1 161 ? -32.635 -27.554 -9.589  1.00 76.47  ? 161 GLU A OE1 1 
ATOM   1289  O OE2 . GLU A 1 161 ? -33.214 -28.513 -11.521 1.00 73.64  ? 161 GLU A OE2 1 
ATOM   1290  N N   . GLY A 1 162 ? -32.039 -34.150 -11.944 1.00 70.05  ? 162 GLY A N   1 
ATOM   1291  C CA  . GLY A 1 162 ? -32.698 -35.070 -12.864 1.00 64.12  ? 162 GLY A CA  1 
ATOM   1292  C C   . GLY A 1 162 ? -33.348 -34.316 -14.021 1.00 66.12  ? 162 GLY A C   1 
ATOM   1293  O O   . GLY A 1 162 ? -34.304 -33.575 -13.820 1.00 74.89  ? 162 GLY A O   1 
ATOM   1294  N N   . MET A 1 163 ? -32.787 -34.449 -15.225 1.00 61.29  ? 163 MET A N   1 
ATOM   1295  C CA  . MET A 1 163 ? -33.420 -33.891 -16.412 1.00 62.54  ? 163 MET A CA  1 
ATOM   1296  C C   . MET A 1 163 ? -33.414 -34.969 -17.485 1.00 58.99  ? 163 MET A C   1 
ATOM   1297  O O   . MET A 1 163 ? -32.615 -35.881 -17.427 1.00 61.72  ? 163 MET A O   1 
ATOM   1298  C CB  . MET A 1 163 ? -32.730 -32.625 -16.948 1.00 56.65  ? 163 MET A CB  1 
ATOM   1299  C CG  . MET A 1 163 ? -31.345 -32.815 -17.599 1.00 55.28  ? 163 MET A CG  1 
ATOM   1300  S SD  . MET A 1 163 ? -30.796 -31.283 -18.499 1.00 59.81  ? 163 MET A SD  1 
ATOM   1301  C CE  . MET A 1 163 ? -29.069 -31.246 -18.013 1.00 55.45  ? 163 MET A CE  1 
ATOM   1302  N N   . ARG A 1 164 ? -34.302 -34.865 -18.471 1.00 69.24  ? 164 ARG A N   1 
ATOM   1303  C CA  . ARG A 1 164 ? -34.314 -35.849 -19.541 1.00 75.68  ? 164 ARG A CA  1 
ATOM   1304  C C   . ARG A 1 164 ? -33.122 -35.591 -20.466 1.00 65.56  ? 164 ARG A C   1 
ATOM   1305  O O   . ARG A 1 164 ? -32.703 -34.452 -20.635 1.00 58.72  ? 164 ARG A O   1 
ATOM   1306  C CB  . ARG A 1 164 ? -35.674 -35.784 -20.242 1.00 89.04  ? 164 ARG A CB  1 
ATOM   1307  C CG  . ARG A 1 164 ? -36.818 -36.370 -19.424 1.00 98.92  ? 164 ARG A CG  1 
ATOM   1308  C CD  . ARG A 1 164 ? -38.168 -36.139 -20.080 1.00 109.25 ? 164 ARG A CD  1 
ATOM   1309  N NE  . ARG A 1 164 ? -38.124 -36.344 -21.528 1.00 120.95 ? 164 ARG A NE  1 
ATOM   1310  C CZ  . ARG A 1 164 ? -38.467 -35.435 -22.439 1.00 120.28 ? 164 ARG A CZ  1 
ATOM   1311  N NH1 . ARG A 1 164 ? -38.998 -34.286 -22.063 1.00 122.34 ? 164 ARG A NH1 1 
ATOM   1312  N NH2 . ARG A 1 164 ? -38.291 -35.684 -23.727 1.00 118.20 ? 164 ARG A NH2 1 
ATOM   1313  N N   . ARG A 1 165 ? -32.600 -36.657 -21.078 1.00 60.87  ? 165 ARG A N   1 
ATOM   1314  C CA  . ARG A 1 165 ? -31.532 -36.581 -22.068 1.00 60.44  ? 165 ARG A CA  1 
ATOM   1315  C C   . ARG A 1 165 ? -31.877 -35.580 -23.179 1.00 66.13  ? 165 ARG A C   1 
ATOM   1316  O O   . ARG A 1 165 ? -30.969 -34.988 -23.776 1.00 61.57  ? 165 ARG A O   1 
ATOM   1317  C CB  . ARG A 1 165 ? -31.254 -37.972 -22.646 1.00 72.03  ? 165 ARG A CB  1 
ATOM   1318  C CG  . ARG A 1 165 ? -31.198 -39.091 -21.605 1.00 90.40  ? 165 ARG A CG  1 
ATOM   1319  C CD  . ARG A 1 165 ? -31.038 -40.495 -22.160 1.00 101.78 ? 165 ARG A CD  1 
ATOM   1320  N NE  . ARG A 1 165 ? -29.686 -40.720 -22.666 1.00 113.96 ? 165 ARG A NE  1 
ATOM   1321  C CZ  . ARG A 1 165 ? -29.383 -41.339 -23.809 1.00 113.40 ? 165 ARG A CZ  1 
ATOM   1322  N NH1 . ARG A 1 165 ? -30.337 -41.870 -24.556 1.00 113.56 ? 165 ARG A NH1 1 
ATOM   1323  N NH2 . ARG A 1 165 ? -28.121 -41.449 -24.189 1.00 96.40  ? 165 ARG A NH2 1 
ATOM   1324  N N   . GLU A 1 166 ? -33.185 -35.396 -23.444 1.00 60.32  ? 166 GLU A N   1 
ATOM   1325  C CA  . GLU A 1 166 ? -33.695 -34.542 -24.508 1.00 63.15  ? 166 GLU A CA  1 
ATOM   1326  C C   . GLU A 1 166 ? -33.531 -33.067 -24.134 1.00 65.49  ? 166 GLU A C   1 
ATOM   1327  O O   . GLU A 1 166 ? -33.505 -32.199 -25.008 1.00 59.41  ? 166 GLU A O   1 
ATOM   1328  C CB  . GLU A 1 166 ? -35.188 -34.826 -24.752 1.00 77.27  ? 166 GLU A CB  1 
ATOM   1329  C CG  . GLU A 1 166 ? -35.514 -36.120 -25.514 1.00 87.44  ? 166 GLU A CG  1 
ATOM   1330  C CD  . GLU A 1 166 ? -35.170 -37.461 -24.863 1.00 92.50  ? 166 GLU A CD  1 
ATOM   1331  O OE1 . GLU A 1 166 ? -34.519 -38.285 -25.532 1.00 76.14  ? 166 GLU A OE1 1 
ATOM   1332  O OE2 . GLU A 1 166 ? -35.559 -37.702 -23.695 1.00 96.32  ? 166 GLU A OE2 1 
ATOM   1333  N N   . GLU A 1 167 ? -33.460 -32.784 -22.825 1.00 59.88  ? 167 GLU A N   1 
ATOM   1334  C CA  . GLU A 1 167 ? -33.316 -31.424 -22.337 1.00 62.73  ? 167 GLU A CA  1 
ATOM   1335  C C   . GLU A 1 167 ? -31.860 -30.954 -22.367 1.00 49.60  ? 167 GLU A C   1 
ATOM   1336  O O   . GLU A 1 167 ? -31.615 -29.780 -22.149 1.00 53.45  ? 167 GLU A O   1 
ATOM   1337  C CB  . GLU A 1 167 ? -33.777 -31.284 -20.886 1.00 78.81  ? 167 GLU A CB  1 
ATOM   1338  C CG  . GLU A 1 167 ? -35.272 -31.443 -20.629 1.00 92.39  ? 167 GLU A CG  1 
ATOM   1339  C CD  . GLU A 1 167 ? -35.594 -31.388 -19.136 1.00 103.16 ? 167 GLU A CD  1 
ATOM   1340  O OE1 . GLU A 1 167 ? -35.434 -30.289 -18.532 1.00 96.98  ? 167 GLU A OE1 1 
ATOM   1341  O OE2 . GLU A 1 167 ? -35.927 -32.461 -18.551 1.00 87.05  ? 167 GLU A OE2 1 
ATOM   1342  N N   . HIS A 1 168 ? -30.904 -31.848 -22.639 1.00 45.73  ? 168 HIS A N   1 
ATOM   1343  C CA  . HIS A 1 168 ? -29.487 -31.529 -22.530 1.00 40.99  ? 168 HIS A CA  1 
ATOM   1344  C C   . HIS A 1 168 ? -29.136 -30.323 -23.380 1.00 43.14  ? 168 HIS A C   1 
ATOM   1345  O O   . HIS A 1 168 ? -28.564 -29.360 -22.877 1.00 38.29  ? 168 HIS A O   1 
ATOM   1346  C CB  . HIS A 1 168 ? -28.599 -32.690 -22.950 1.00 36.01  ? 168 HIS A CB  1 
ATOM   1347  C CG  . HIS A 1 168 ? -28.500 -33.744 -21.900 1.00 43.61  ? 168 HIS A CG  1 
ATOM   1348  N ND1 . HIS A 1 168 ? -27.671 -34.843 -22.013 1.00 44.68  ? 168 HIS A ND1 1 
ATOM   1349  C CD2 . HIS A 1 168 ? -29.152 -33.874 -20.732 1.00 43.07  ? 168 HIS A CD2 1 
ATOM   1350  C CE1 . HIS A 1 168 ? -27.822 -35.602 -20.940 1.00 45.36  ? 168 HIS A CE1 1 
ATOM   1351  N NE2 . HIS A 1 168 ? -28.711 -35.033 -20.153 1.00 40.89  ? 168 HIS A NE2 1 
ATOM   1352  N N   . TRP A 1 169 ? -29.537 -30.383 -24.652 1.00 42.05  ? 169 TRP A N   1 
ATOM   1353  C CA  . TRP A 1 169 ? -29.094 -29.407 -25.624 1.00 45.28  ? 169 TRP A CA  1 
ATOM   1354  C C   . TRP A 1 169 ? -29.599 -28.016 -25.237 1.00 46.37  ? 169 TRP A C   1 
ATOM   1355  O O   . TRP A 1 169 ? -28.981 -26.998 -25.576 1.00 48.59  ? 169 TRP A O   1 
ATOM   1356  C CB  . TRP A 1 169 ? -29.523 -29.836 -27.027 1.00 46.87  ? 169 TRP A CB  1 
ATOM   1357  C CG  . TRP A 1 169 ? -30.994 -29.700 -27.268 1.00 46.08  ? 169 TRP A CG  1 
ATOM   1358  C CD1 . TRP A 1 169 ? -31.921 -30.702 -27.240 1.00 48.74  ? 169 TRP A CD1 1 
ATOM   1359  C CD2 . TRP A 1 169 ? -31.706 -28.495 -27.596 1.00 46.16  ? 169 TRP A CD2 1 
ATOM   1360  N NE1 . TRP A 1 169 ? -33.164 -30.204 -27.520 1.00 51.85  ? 169 TRP A NE1 1 
ATOM   1361  C CE2 . TRP A 1 169 ? -33.067 -28.859 -27.750 1.00 48.11  ? 169 TRP A CE2 1 
ATOM   1362  C CE3 . TRP A 1 169 ? -31.331 -27.154 -27.800 1.00 45.86  ? 169 TRP A CE3 1 
ATOM   1363  C CZ2 . TRP A 1 169 ? -34.048 -27.927 -28.064 1.00 46.52  ? 169 TRP A CZ2 1 
ATOM   1364  C CZ3 . TRP A 1 169 ? -32.309 -26.231 -28.113 1.00 50.61  ? 169 TRP A CZ3 1 
ATOM   1365  C CH2 . TRP A 1 169 ? -33.647 -26.616 -28.254 1.00 50.32  ? 169 TRP A CH2 1 
ATOM   1366  N N   . GLU A 1 170 ? -30.701 -27.981 -24.483 1.00 46.03  ? 170 GLU A N   1 
ATOM   1367  C CA  . GLU A 1 170 ? -31.329 -26.733 -24.100 1.00 45.63  ? 170 GLU A CA  1 
ATOM   1368  C C   . GLU A 1 170 ? -30.473 -26.080 -23.017 1.00 46.20  ? 170 GLU A C   1 
ATOM   1369  O O   . GLU A 1 170 ? -30.214 -24.881 -23.072 1.00 49.89  ? 170 GLU A O   1 
ATOM   1370  C CB  . GLU A 1 170 ? -32.764 -26.986 -23.616 1.00 52.54  ? 170 GLU A CB  1 
ATOM   1371  C CG  . GLU A 1 170 ? -33.718 -27.461 -24.705 1.00 61.07  ? 170 GLU A CG  1 
ATOM   1372  C CD  . GLU A 1 170 ? -35.193 -27.538 -24.320 1.00 72.98  ? 170 GLU A CD  1 
ATOM   1373  O OE1 . GLU A 1 170 ? -35.755 -28.654 -24.321 1.00 78.91  ? 170 GLU A OE1 1 
ATOM   1374  O OE2 . GLU A 1 170 ? -35.789 -26.488 -24.043 1.00 69.52  ? 170 GLU A OE2 1 
ATOM   1375  N N   . ALA A 1 171 ? -30.031 -26.887 -22.046 1.00 43.65  ? 171 ALA A N   1 
ATOM   1376  C CA  . ALA A 1 171 ? -29.218 -26.406 -20.937 1.00 40.36  ? 171 ALA A CA  1 
ATOM   1377  C C   . ALA A 1 171 ? -27.801 -26.055 -21.424 1.00 43.30  ? 171 ALA A C   1 
ATOM   1378  O O   . ALA A 1 171 ? -27.214 -25.080 -20.978 1.00 49.50  ? 171 ALA A O   1 
ATOM   1379  C CB  . ALA A 1 171 ? -29.233 -27.447 -19.861 1.00 40.08  ? 171 ALA A CB  1 
ATOM   1380  N N   . MET A 1 172 ? -27.298 -26.760 -22.439 1.00 38.66  ? 172 MET A N   1 
ATOM   1381  C CA  . MET A 1 172 ? -26.055 -26.402 -23.092 1.00 39.29  ? 172 MET A CA  1 
ATOM   1382  C C   . MET A 1 172 ? -26.157 -25.071 -23.857 1.00 42.86  ? 172 MET A C   1 
ATOM   1383  O O   . MET A 1 172 ? -25.193 -24.296 -23.900 1.00 41.52  ? 172 MET A O   1 
ATOM   1384  C CB  . MET A 1 172 ? -25.654 -27.518 -24.064 1.00 40.86  ? 172 MET A CB  1 
ATOM   1385  C CG  . MET A 1 172 ? -25.221 -28.812 -23.394 1.00 43.13  ? 172 MET A CG  1 
ATOM   1386  S SD  . MET A 1 172 ? -23.586 -28.774 -22.538 1.00 49.04  ? 172 MET A SD  1 
ATOM   1387  C CE  . MET A 1 172 ? -22.615 -27.796 -23.673 1.00 50.93  ? 172 MET A CE  1 
ATOM   1388  N N   . LEU A 1 173 ? -27.307 -24.760 -24.475 1.00 38.67  ? 173 LEU A N   1 
ATOM   1389  C CA  . LEU A 1 173 ? -27.391 -23.510 -25.237 1.00 39.56  ? 173 LEU A CA  1 
ATOM   1390  C C   . LEU A 1 173 ? -27.395 -22.317 -24.281 1.00 43.88  ? 173 LEU A C   1 
ATOM   1391  O O   . LEU A 1 173 ? -26.766 -21.285 -24.532 1.00 43.38  ? 173 LEU A O   1 
ATOM   1392  C CB  . LEU A 1 173 ? -28.657 -23.528 -26.100 1.00 39.94  ? 173 LEU A CB  1 
ATOM   1393  C CG  . LEU A 1 173 ? -29.037 -22.216 -26.774 1.00 39.70  ? 173 LEU A CG  1 
ATOM   1394  C CD1 . LEU A 1 173 ? -28.006 -21.781 -27.788 1.00 41.42  ? 173 LEU A CD1 1 
ATOM   1395  C CD2 . LEU A 1 173 ? -30.401 -22.338 -27.441 1.00 45.86  ? 173 LEU A CD2 1 
ATOM   1396  N N   . GLU A 1 174 ? -28.176 -22.469 -23.214 1.00 39.36  ? 174 GLU A N   1 
ATOM   1397  C CA  . GLU A 1 174 ? -28.319 -21.464 -22.181 1.00 43.51  ? 174 GLU A CA  1 
ATOM   1398  C C   . GLU A 1 174 ? -26.939 -21.150 -21.593 1.00 47.11  ? 174 GLU A C   1 
ATOM   1399  O O   . GLU A 1 174 ? -26.532 -19.993 -21.532 1.00 48.75  ? 174 GLU A O   1 
ATOM   1400  C CB  . GLU A 1 174 ? -29.310 -21.988 -21.131 1.00 45.98  ? 174 GLU A CB  1 
ATOM   1401  C CG  . GLU A 1 174 ? -29.803 -20.921 -20.174 1.00 57.47  ? 174 GLU A CG  1 
ATOM   1402  C CD  . GLU A 1 174 ? -30.629 -19.823 -20.817 1.00 60.76  ? 174 GLU A CD  1 
ATOM   1403  O OE1 . GLU A 1 174 ? -31.122 -20.028 -21.957 1.00 70.51  ? 174 GLU A OE1 1 
ATOM   1404  O OE2 . GLU A 1 174 ? -30.768 -18.761 -20.179 1.00 66.45  ? 174 GLU A OE2 1 
ATOM   1405  N N   . ASP A 1 175 ? -26.209 -22.189 -21.174 1.00 45.20  ? 175 ASP A N   1 
ATOM   1406  C CA  . ASP A 1 175 ? -24.876 -22.022 -20.627 1.00 40.89  ? 175 ASP A CA  1 
ATOM   1407  C C   . ASP A 1 175 ? -23.966 -21.334 -21.627 1.00 45.36  ? 175 ASP A C   1 
ATOM   1408  O O   . ASP A 1 175 ? -23.228 -20.412 -21.252 1.00 43.09  ? 175 ASP A O   1 
ATOM   1409  C CB  . ASP A 1 175 ? -24.283 -23.367 -20.213 1.00 48.73  ? 175 ASP A CB  1 
ATOM   1410  C CG  . ASP A 1 175 ? -24.668 -23.741 -18.796 1.00 41.61  ? 175 ASP A CG  1 
ATOM   1411  O OD1 . ASP A 1 175 ? -25.117 -22.821 -18.061 1.00 41.01  ? 175 ASP A OD1 1 
ATOM   1412  O OD2 . ASP A 1 175 ? -24.504 -24.916 -18.445 1.00 38.80  ? 175 ASP A OD2 1 
ATOM   1413  N N   . SER A 1 176 ? -24.069 -21.754 -22.892 1.00 41.81  ? 176 SER A N   1 
ATOM   1414  C CA  . SER A 1 176 ? -23.243 -21.188 -23.946 1.00 42.89  ? 176 SER A CA  1 
ATOM   1415  C C   . SER A 1 176 ? -23.503 -19.701 -24.146 1.00 42.16  ? 176 SER A C   1 
ATOM   1416  O O   . SER A 1 176 ? -22.577 -18.943 -24.455 1.00 47.05  ? 176 SER A O   1 
ATOM   1417  C CB  . SER A 1 176 ? -23.436 -21.925 -25.245 1.00 42.09  ? 176 SER A CB  1 
ATOM   1418  O OG  . SER A 1 176 ? -23.085 -23.289 -25.094 1.00 41.90  ? 176 SER A OG  1 
ATOM   1419  N N   . LEU A 1 177 ? -24.769 -19.298 -24.069 1.00 42.01  ? 177 LEU A N   1 
ATOM   1420  C CA  . LEU A 1 177 ? -25.112 -17.893 -24.235 1.00 42.10  ? 177 LEU A CA  1 
ATOM   1421  C C   . LEU A 1 177 ? -24.449 -17.116 -23.101 1.00 37.13  ? 177 LEU A C   1 
ATOM   1422  O O   . LEU A 1 177 ? -23.817 -16.113 -23.338 1.00 37.46  ? 177 LEU A O   1 
ATOM   1423  C CB  . LEU A 1 177 ? -26.638 -17.706 -24.190 1.00 38.89  ? 177 LEU A CB  1 
ATOM   1424  C CG  . LEU A 1 177 ? -27.435 -18.146 -25.419 1.00 42.60  ? 177 LEU A CG  1 
ATOM   1425  C CD1 . LEU A 1 177 ? -28.945 -18.147 -25.142 1.00 44.20  ? 177 LEU A CD1 1 
ATOM   1426  C CD2 . LEU A 1 177 ? -27.126 -17.247 -26.583 1.00 43.83  ? 177 LEU A CD2 1 
ATOM   1427  N N   . ASN A 1 178 ? -24.623 -17.593 -21.866 1.00 34.81  ? 178 ASN A N   1 
ATOM   1428  C CA  . ASN A 1 178 ? -23.987 -16.993 -20.712 1.00 37.23  ? 178 ASN A CA  1 
ATOM   1429  C C   . ASN A 1 178 ? -22.472 -16.924 -20.929 1.00 36.76  ? 178 ASN A C   1 
ATOM   1430  O O   . ASN A 1 178 ? -21.859 -15.887 -20.735 1.00 35.07  ? 178 ASN A O   1 
ATOM   1431  C CB  . ASN A 1 178 ? -24.386 -17.751 -19.445 1.00 38.21  ? 178 ASN A CB  1 
ATOM   1432  C CG  . ASN A 1 178 ? -25.820 -17.489 -19.072 1.00 41.30  ? 178 ASN A CG  1 
ATOM   1433  O OD1 . ASN A 1 178 ? -26.375 -16.476 -19.470 1.00 45.68  ? 178 ASN A OD1 1 
ATOM   1434  N ND2 . ASN A 1 178 ? -26.398 -18.348 -18.259 1.00 44.02  ? 178 ASN A ND2 1 
ATOM   1435  N N   . MET A 1 179 ? -21.855 -18.019 -21.370 1.00 37.44  ? 179 MET A N   1 
ATOM   1436  C CA  . MET A 1 179 ? -20.402 -18.065 -21.384 1.00 37.03  ? 179 MET A CA  1 
ATOM   1437  C C   . MET A 1 179 ? -19.868 -17.195 -22.523 1.00 39.82  ? 179 MET A C   1 
ATOM   1438  O O   . MET A 1 179 ? -18.885 -16.479 -22.342 1.00 44.85  ? 179 MET A O   1 
ATOM   1439  C CB  . MET A 1 179 ? -19.869 -19.496 -21.524 1.00 41.53  ? 179 MET A CB  1 
ATOM   1440  C CG  . MET A 1 179 ? -18.357 -19.552 -21.379 1.00 39.48  ? 179 MET A CG  1 
ATOM   1441  S SD  . MET A 1 179 ? -17.673 -21.163 -21.689 1.00 43.20  ? 179 MET A SD  1 
ATOM   1442  C CE  . MET A 1 179 ? -17.756 -21.145 -23.480 1.00 40.59  ? 179 MET A CE  1 
ATOM   1443  N N   . LEU A 1 180 ? -20.505 -17.249 -23.691 1.00 36.42  ? 180 LEU A N   1 
ATOM   1444  C CA  . LEU A 1 180 ? -20.025 -16.469 -24.815 1.00 40.23  ? 180 LEU A CA  1 
ATOM   1445  C C   . LEU A 1 180 ? -20.102 -14.986 -24.444 1.00 44.10  ? 180 LEU A C   1 
ATOM   1446  O O   . LEU A 1 180 ? -19.155 -14.223 -24.687 1.00 39.54  ? 180 LEU A O   1 
ATOM   1447  C CB  . LEU A 1 180 ? -20.864 -16.794 -26.055 1.00 38.58  ? 180 LEU A CB  1 
ATOM   1448  C CG  . LEU A 1 180 ? -20.614 -18.157 -26.708 1.00 38.14  ? 180 LEU A CG  1 
ATOM   1449  C CD1 . LEU A 1 180 ? -21.532 -18.324 -27.901 1.00 39.74  ? 180 LEU A CD1 1 
ATOM   1450  C CD2 . LEU A 1 180 ? -19.171 -18.333 -27.123 1.00 35.13  ? 180 LEU A CD2 1 
ATOM   1451  N N   . ALA A 1 181 ? -21.226 -14.595 -23.830 1.00 40.04  ? 181 ALA A N   1 
ATOM   1452  C CA  . ALA A 1 181 ? -21.381 -13.239 -23.323 1.00 39.89  ? 181 ALA A CA  1 
ATOM   1453  C C   . ALA A 1 181 ? -20.256 -12.846 -22.353 1.00 38.72  ? 181 ALA A C   1 
ATOM   1454  O O   . ALA A 1 181 ? -19.788 -11.712 -22.386 1.00 35.95  ? 181 ALA A O   1 
ATOM   1455  C CB  . ALA A 1 181 ? -22.734 -13.092 -22.667 1.00 40.51  ? 181 ALA A CB  1 
ATOM   1456  N N   . ALA A 1 182 ? -19.792 -13.770 -21.505 1.00 35.96  ? 182 ALA A N   1 
ATOM   1457  C CA  . ALA A 1 182 ? -18.798 -13.424 -20.491 1.00 40.08  ? 182 ALA A CA  1 
ATOM   1458  C C   . ALA A 1 182 ? -17.387 -13.308 -21.068 1.00 39.03  ? 182 ALA A C   1 
ATOM   1459  O O   . ALA A 1 182 ? -16.558 -12.566 -20.548 1.00 42.43  ? 182 ALA A O   1 
ATOM   1460  C CB  . ALA A 1 182 ? -18.815 -14.442 -19.376 1.00 40.65  ? 182 ALA A CB  1 
ATOM   1461  N N   . LEU A 1 183 ? -17.080 -14.052 -22.128 1.00 37.91  ? 183 LEU A N   1 
ATOM   1462  C CA  . LEU A 1 183 ? -15.694 -14.194 -22.537 1.00 33.92  ? 183 LEU A CA  1 
ATOM   1463  C C   . LEU A 1 183 ? -15.078 -12.831 -22.871 1.00 37.69  ? 183 LEU A C   1 
ATOM   1464  O O   . LEU A 1 183 ? -13.927 -12.529 -22.548 1.00 41.69  ? 183 LEU A O   1 
ATOM   1465  C CB  . LEU A 1 183 ? -15.639 -15.119 -23.758 1.00 33.45  ? 183 LEU A CB  1 
ATOM   1466  C CG  . LEU A 1 183 ? -15.937 -16.595 -23.516 1.00 36.44  ? 183 LEU A CG  1 
ATOM   1467  C CD1 . LEU A 1 183 ? -15.502 -17.411 -24.703 1.00 33.03  ? 183 LEU A CD1 1 
ATOM   1468  C CD2 . LEU A 1 183 ? -15.278 -17.126 -22.262 1.00 34.23  ? 183 LEU A CD2 1 
ATOM   1469  N N   . PRO A 1 184 ? -15.758 -11.960 -23.628 1.00 35.15  ? 184 PRO A N   1 
ATOM   1470  C CA  . PRO A 1 184 ? -15.179 -10.668 -23.946 1.00 37.91  ? 184 PRO A CA  1 
ATOM   1471  C C   . PRO A 1 184 ? -14.878 -9.888  -22.674 1.00 37.14  ? 184 PRO A C   1 
ATOM   1472  O O   . PRO A 1 184 ? -13.864 -9.209  -22.628 1.00 31.07  ? 184 PRO A O   1 
ATOM   1473  C CB  . PRO A 1 184 ? -16.248 -9.993  -24.792 1.00 36.01  ? 184 PRO A CB  1 
ATOM   1474  C CG  . PRO A 1 184 ? -17.013 -11.145 -25.380 1.00 37.96  ? 184 PRO A CG  1 
ATOM   1475  C CD  . PRO A 1 184 ? -17.046 -12.179 -24.286 1.00 40.70  ? 184 PRO A CD  1 
ATOM   1476  N N   . VAL A 1 185 ? -15.738 -10.033 -21.654 1.00 38.38  ? 185 VAL A N   1 
ATOM   1477  C CA  . VAL A 1 185 ? -15.567 -9.321  -20.396 1.00 37.93  ? 185 VAL A CA  1 
ATOM   1478  C C   . VAL A 1 185 ? -14.336 -9.851  -19.656 1.00 37.03  ? 185 VAL A C   1 
ATOM   1479  O O   . VAL A 1 185 ? -13.553 -9.057  -19.166 1.00 35.08  ? 185 VAL A O   1 
ATOM   1480  C CB  . VAL A 1 185 ? -16.829 -9.391  -19.519 1.00 38.20  ? 185 VAL A CB  1 
ATOM   1481  C CG1 . VAL A 1 185 ? -16.665 -8.588  -18.223 1.00 38.39  ? 185 VAL A CG1 1 
ATOM   1482  C CG2 . VAL A 1 185 ? -18.048 -8.901  -20.278 1.00 43.19  ? 185 VAL A CG2 1 
ATOM   1483  N N   . ILE A 1 186 ? -14.165 -11.176 -19.592 1.00 36.90  ? 186 ILE A N   1 
ATOM   1484  C CA  . ILE A 1 186 ? -13.025 -11.804 -18.926 1.00 38.00  ? 186 ILE A CA  1 
ATOM   1485  C C   . ILE A 1 186 ? -11.725 -11.454 -19.665 1.00 39.55  ? 186 ILE A C   1 
ATOM   1486  O O   . ILE A 1 186 ? -10.726 -11.052 -19.066 1.00 37.35  ? 186 ILE A O   1 
ATOM   1487  C CB  . ILE A 1 186 ? -13.278 -13.320 -18.799 1.00 36.69  ? 186 ILE A CB  1 
ATOM   1488  C CG1 . ILE A 1 186 ? -14.475 -13.600 -17.897 1.00 40.10  ? 186 ILE A CG1 1 
ATOM   1489  C CG2 . ILE A 1 186 ? -12.044 -14.060 -18.318 1.00 39.96  ? 186 ILE A CG2 1 
ATOM   1490  C CD1 . ILE A 1 186 ? -14.951 -15.065 -17.841 1.00 42.84  ? 186 ILE A CD1 1 
ATOM   1491  N N   . ALA A 1 187 ? -11.755 -11.554 -20.987 1.00 34.45  ? 187 ALA A N   1 
ATOM   1492  C CA  . ALA A 1 187 ? -10.601 -11.239 -21.809 1.00 36.62  ? 187 ALA A CA  1 
ATOM   1493  C C   . ALA A 1 187 ? -10.166 -9.778  -21.683 1.00 36.97  ? 187 ALA A C   1 
ATOM   1494  O O   . ALA A 1 187 ? -8.972  -9.488  -21.557 1.00 36.56  ? 187 ALA A O   1 
ATOM   1495  C CB  . ALA A 1 187 ? -10.931 -11.562 -23.241 1.00 32.66  ? 187 ALA A CB  1 
ATOM   1496  N N   . ALA A 1 188 ? -11.113 -8.853  -21.791 1.00 30.91  ? 188 ALA A N   1 
ATOM   1497  C CA  . ALA A 1 188 ? -10.786 -7.439  -21.628 1.00 33.83  ? 188 ALA A CA  1 
ATOM   1498  C C   . ALA A 1 188 ? -10.266 -7.160  -20.217 1.00 34.89  ? 188 ALA A C   1 
ATOM   1499  O O   . ALA A 1 188 ? -9.308  -6.396  -20.058 1.00 38.39  ? 188 ALA A O   1 
ATOM   1500  C CB  . ALA A 1 188 ? -11.976 -6.575  -21.919 1.00 34.80  ? 188 ALA A CB  1 
ATOM   1501  N N   . TYR A 1 189 ? -10.838 -7.820  -19.194 1.00 30.45  ? 189 TYR A N   1 
ATOM   1502  C CA  . TYR A 1 189 ? -10.362 -7.578  -17.837 1.00 35.50  ? 189 TYR A CA  1 
ATOM   1503  C C   . TYR A 1 189 ? -8.867  -7.914  -17.733 1.00 34.75  ? 189 TYR A C   1 
ATOM   1504  O O   . TYR A 1 189 ? -8.078  -7.113  -17.253 1.00 30.84  ? 189 TYR A O   1 
ATOM   1505  C CB  . TYR A 1 189 ? -11.205 -8.340  -16.822 1.00 37.67  ? 189 TYR A CB  1 
ATOM   1506  C CG  . TYR A 1 189 ? -10.969 -7.909  -15.399 1.00 39.74  ? 189 TYR A CG  1 
ATOM   1507  C CD1 . TYR A 1 189 ? -9.937  -8.437  -14.634 1.00 37.14  ? 189 TYR A CD1 1 
ATOM   1508  C CD2 . TYR A 1 189 ? -11.772 -6.930  -14.835 1.00 38.68  ? 189 TYR A CD2 1 
ATOM   1509  C CE1 . TYR A 1 189 ? -9.722  -8.006  -13.333 1.00 37.85  ? 189 TYR A CE1 1 
ATOM   1510  C CE2 . TYR A 1 189 ? -11.569 -6.487  -13.545 1.00 38.78  ? 189 TYR A CE2 1 
ATOM   1511  C CZ  . TYR A 1 189 ? -10.539 -7.018  -12.795 1.00 43.81  ? 189 TYR A CZ  1 
ATOM   1512  O OH  . TYR A 1 189 ? -10.435 -6.550  -11.500 1.00 55.92  ? 189 TYR A OH  1 
ATOM   1513  N N   . ILE A 1 190 ? -8.508  -9.119  -18.181 1.00 30.54  ? 190 ILE A N   1 
ATOM   1514  C CA  . ILE A 1 190 ? -7.145  -9.587  -18.293 1.00 32.42  ? 190 ILE A CA  1 
ATOM   1515  C C   . ILE A 1 190 ? -6.298  -8.541  -19.015 1.00 33.67  ? 190 ILE A C   1 
ATOM   1516  O O   . ILE A 1 190 ? -5.241  -8.160  -18.534 1.00 34.88  ? 190 ILE A O   1 
ATOM   1517  C CB  . ILE A 1 190 ? -7.120  -10.971 -18.991 1.00 32.81  ? 190 ILE A CB  1 
ATOM   1518  C CG1 . ILE A 1 190 ? -7.805  -12.011 -18.108 1.00 33.59  ? 190 ILE A CG1 1 
ATOM   1519  C CG2 . ILE A 1 190 ? -5.682  -11.361 -19.317 1.00 32.40  ? 190 ILE A CG2 1 
ATOM   1520  C CD1 . ILE A 1 190 ? -8.207  -13.280 -18.825 1.00 40.11  ? 190 ILE A CD1 1 
ATOM   1521  N N   . TYR A 1 191 ? -6.770  -8.092  -20.173 1.00 34.82  ? 191 TYR A N   1 
ATOM   1522  C CA  . TYR A 1 191 ? -6.023  -7.186  -21.025 1.00 35.01  ? 191 TYR A CA  1 
ATOM   1523  C C   . TYR A 1 191 ? -5.724  -5.893  -20.274 1.00 35.49  ? 191 TYR A C   1 
ATOM   1524  O O   . TYR A 1 191 ? -4.601  -5.395  -20.279 1.00 37.56  ? 191 TYR A O   1 
ATOM   1525  C CB  . TYR A 1 191 ? -6.814  -6.898  -22.314 1.00 34.37  ? 191 TYR A CB  1 
ATOM   1526  C CG  . TYR A 1 191 ? -6.027  -6.120  -23.331 1.00 38.13  ? 191 TYR A CG  1 
ATOM   1527  C CD1 . TYR A 1 191 ? -5.082  -6.740  -24.133 1.00 34.78  ? 191 TYR A CD1 1 
ATOM   1528  C CD2 . TYR A 1 191 ? -6.196  -4.750  -23.467 1.00 37.98  ? 191 TYR A CD2 1 
ATOM   1529  C CE1 . TYR A 1 191 ? -4.333  -6.015  -25.035 1.00 34.35  ? 191 TYR A CE1 1 
ATOM   1530  C CE2 . TYR A 1 191 ? -5.481  -4.021  -24.404 1.00 33.17  ? 191 TYR A CE2 1 
ATOM   1531  C CZ  . TYR A 1 191 ? -4.511  -4.649  -25.152 1.00 35.43  ? 191 TYR A CZ  1 
ATOM   1532  O OH  . TYR A 1 191 ? -3.770  -3.907  -26.048 1.00 41.03  ? 191 TYR A OH  1 
ATOM   1533  N N   . ARG A 1 192 ? -6.768  -5.301  -19.693 1.00 38.35  ? 192 ARG A N   1 
ATOM   1534  C CA  . ARG A 1 192 ? -6.645  -3.988  -19.088 1.00 36.15  ? 192 ARG A CA  1 
ATOM   1535  C C   . ARG A 1 192 ? -5.757  -4.079  -17.849 1.00 36.30  ? 192 ARG A C   1 
ATOM   1536  O O   . ARG A 1 192 ? -4.931  -3.184  -17.633 1.00 34.66  ? 192 ARG A O   1 
ATOM   1537  C CB  . ARG A 1 192 ? -8.028  -3.427  -18.749 1.00 38.98  ? 192 ARG A CB  1 
ATOM   1538  C CG  . ARG A 1 192 ? -8.961  -3.179  -19.939 1.00 36.74  ? 192 ARG A CG  1 
ATOM   1539  C CD  . ARG A 1 192 ? -8.428  -2.124  -20.893 1.00 34.62  ? 192 ARG A CD  1 
ATOM   1540  N NE  . ARG A 1 192 ? -8.256  -0.844  -20.241 1.00 33.10  ? 192 ARG A NE  1 
ATOM   1541  C CZ  . ARG A 1 192 ? -7.867  0.269   -20.837 1.00 36.38  ? 192 ARG A CZ  1 
ATOM   1542  N NH1 . ARG A 1 192 ? -7.590  0.264   -22.128 1.00 38.01  ? 192 ARG A NH1 1 
ATOM   1543  N NH2 . ARG A 1 192 ? -7.743  1.384   -20.137 1.00 33.23  ? 192 ARG A NH2 1 
ATOM   1544  N N   . ARG A 1 193 ? -5.898  -5.182  -17.090 1.00 35.94  ? 193 ARG A N   1 
ATOM   1545  C CA  . ARG A 1 193 ? -5.182  -5.351  -15.837 1.00 37.39  ? 193 ARG A CA  1 
ATOM   1546  C C   . ARG A 1 193 ? -3.703  -5.588  -16.102 1.00 36.18  ? 193 ARG A C   1 
ATOM   1547  O O   . ARG A 1 193 ? -2.852  -4.984  -15.459 1.00 35.34  ? 193 ARG A O   1 
ATOM   1548  C CB  . ARG A 1 193 ? -5.753  -6.503  -15.019 1.00 33.42  ? 193 ARG A CB  1 
ATOM   1549  C CG  . ARG A 1 193 ? -4.964  -6.730  -13.750 1.00 33.22  ? 193 ARG A CG  1 
ATOM   1550  C CD  . ARG A 1 193 ? -5.570  -7.732  -12.815 1.00 33.89  ? 193 ARG A CD  1 
ATOM   1551  N NE  . ARG A 1 193 ? -4.745  -7.828  -11.614 1.00 39.04  ? 193 ARG A NE  1 
ATOM   1552  C CZ  . ARG A 1 193 ? -4.253  -8.958  -11.107 1.00 39.39  ? 193 ARG A CZ  1 
ATOM   1553  N NH1 . ARG A 1 193 ? -4.478  -10.115 -11.705 1.00 36.12  ? 193 ARG A NH1 1 
ATOM   1554  N NH2 . ARG A 1 193 ? -3.554  -8.926  -9.988  1.00 34.64  ? 193 ARG A NH2 1 
ATOM   1555  N N   . LYS A 1 194 ? -3.421  -6.423  -17.108 1.00 36.07  ? 194 LYS A N   1 
ATOM   1556  C CA  . LYS A 1 194 ? -2.055  -6.766  -17.464 1.00 37.08  ? 194 LYS A CA  1 
ATOM   1557  C C   . LYS A 1 194 ? -1.348  -5.617  -18.179 1.00 37.50  ? 194 LYS A C   1 
ATOM   1558  O O   . LYS A 1 194 ? -0.177  -5.382  -17.911 1.00 35.85  ? 194 LYS A O   1 
ATOM   1559  C CB  . LYS A 1 194 ? -2.003  -8.003  -18.364 1.00 37.89  ? 194 LYS A CB  1 
ATOM   1560  C CG  . LYS A 1 194 ? -2.136  -9.334  -17.630 1.00 33.65  ? 194 LYS A CG  1 
ATOM   1561  C CD  . LYS A 1 194 ? -1.709  -10.511 -18.480 1.00 34.99  ? 194 LYS A CD  1 
ATOM   1562  C CE  . LYS A 1 194 ? -0.208  -10.624 -18.709 1.00 36.27  ? 194 LYS A CE  1 
ATOM   1563  N NZ  . LYS A 1 194 ? 0.544   -11.053 -17.489 1.00 34.97  ? 194 LYS A NZ  1 
ATOM   1564  N N   . TYR A 1 195 ? -2.022  -4.928  -19.102 1.00 36.32  ? 195 TYR A N   1 
ATOM   1565  C CA  . TYR A 1 195 ? -1.266  -4.117  -20.049 1.00 38.14  ? 195 TYR A CA  1 
ATOM   1566  C C   . TYR A 1 195 ? -1.678  -2.640  -20.057 1.00 36.14  ? 195 TYR A C   1 
ATOM   1567  O O   . TYR A 1 195 ? -1.050  -1.830  -20.741 1.00 36.16  ? 195 TYR A O   1 
ATOM   1568  C CB  . TYR A 1 195 ? -1.384  -4.698  -21.463 1.00 36.56  ? 195 TYR A CB  1 
ATOM   1569  C CG  . TYR A 1 195 ? -1.080  -6.171  -21.572 1.00 39.25  ? 195 TYR A CG  1 
ATOM   1570  C CD1 . TYR A 1 195 ? 0.193   -6.672  -21.346 1.00 40.89  ? 195 TYR A CD1 1 
ATOM   1571  C CD2 . TYR A 1 195 ? -2.060  -7.057  -21.955 1.00 41.63  ? 195 TYR A CD2 1 
ATOM   1572  C CE1 . TYR A 1 195 ? 0.464   -8.021  -21.455 1.00 37.33  ? 195 TYR A CE1 1 
ATOM   1573  C CE2 . TYR A 1 195 ? -1.809  -8.412  -22.071 1.00 44.30  ? 195 TYR A CE2 1 
ATOM   1574  C CZ  . TYR A 1 195 ? -0.544  -8.893  -21.824 1.00 41.24  ? 195 TYR A CZ  1 
ATOM   1575  O OH  . TYR A 1 195 ? -0.378  -10.245 -21.930 1.00 41.40  ? 195 TYR A OH  1 
ATOM   1576  N N   . LYS A 1 196 ? -2.759  -2.277  -19.377 1.00 33.96  ? 196 LYS A N   1 
ATOM   1577  C CA  . LYS A 1 196 ? -3.306  -0.953  -19.612 1.00 39.30  ? 196 LYS A CA  1 
ATOM   1578  C C   . LYS A 1 196 ? -3.532  -0.251  -18.279 1.00 38.46  ? 196 LYS A C   1 
ATOM   1579  O O   . LYS A 1 196 ? -4.444  0.527   -18.153 1.00 47.01  ? 196 LYS A O   1 
ATOM   1580  C CB  . LYS A 1 196 ? -4.569  -1.073  -20.464 1.00 36.00  ? 196 LYS A CB  1 
ATOM   1581  C CG  . LYS A 1 196 ? -4.345  -1.563  -21.888 1.00 36.30  ? 196 LYS A CG  1 
ATOM   1582  C CD  . LYS A 1 196 ? -3.631  -0.564  -22.766 1.00 38.54  ? 196 LYS A CD  1 
ATOM   1583  C CE  . LYS A 1 196 ? -3.013  -1.244  -23.965 1.00 44.43  ? 196 LYS A CE  1 
ATOM   1584  N NZ  . LYS A 1 196 ? -2.565  -0.274  -24.978 1.00 47.71  ? 196 LYS A NZ  1 
ATOM   1585  N N   . GLY A 1 197 ? -2.720  -0.576  -17.277 1.00 43.90  ? 197 GLY A N   1 
ATOM   1586  C CA  . GLY A 1 197 ? -2.744  0.144   -16.017 1.00 42.29  ? 197 GLY A CA  1 
ATOM   1587  C C   . GLY A 1 197 ? -3.973  -0.152  -15.166 1.00 36.87  ? 197 GLY A C   1 
ATOM   1588  O O   . GLY A 1 197 ? -4.332  0.661   -14.323 1.00 40.55  ? 197 GLY A O   1 
ATOM   1589  N N   . ASP A 1 198 ? -4.629  -1.283  -15.404 1.00 39.54  ? 198 ASP A N   1 
ATOM   1590  C CA  . ASP A 1 198 ? -5.663  -1.810  -14.521 1.00 36.32  ? 198 ASP A CA  1 
ATOM   1591  C C   . ASP A 1 198 ? -6.789  -0.786  -14.361 1.00 38.76  ? 198 ASP A C   1 
ATOM   1592  O O   . ASP A 1 198 ? -7.276  -0.572  -13.257 1.00 40.35  ? 198 ASP A O   1 
ATOM   1593  C CB  . ASP A 1 198 ? -5.021  -2.169  -13.172 1.00 37.81  ? 198 ASP A CB  1 
ATOM   1594  C CG  . ASP A 1 198 ? -5.779  -3.098  -12.239 1.00 37.00  ? 198 ASP A CG  1 
ATOM   1595  O OD1 . ASP A 1 198 ? -6.774  -3.756  -12.694 1.00 36.25  ? 198 ASP A OD1 1 
ATOM   1596  O OD2 . ASP A 1 198 ? -5.389  -3.127  -11.049 1.00 35.36  ? 198 ASP A OD2 1 
ATOM   1597  N N   . THR A 1 199 ? -7.133  -0.107  -15.456 1.00 36.80  ? 199 THR A N   1 
ATOM   1598  C CA  . THR A 1 199 ? -8.336  0.700   -15.553 1.00 37.99  ? 199 THR A CA  1 
ATOM   1599  C C   . THR A 1 199 ? -9.295  -0.082  -16.441 1.00 39.90  ? 199 THR A C   1 
ATOM   1600  O O   . THR A 1 199 ? -8.872  -0.684  -17.433 1.00 43.59  ? 199 THR A O   1 
ATOM   1601  C CB  . THR A 1 199 ? -8.026  2.131   -16.029 1.00 43.64  ? 199 THR A CB  1 
ATOM   1602  O OG1 . THR A 1 199 ? -7.443  2.192   -17.329 1.00 40.27  ? 199 THR A OG1 1 
ATOM   1603  C CG2 . THR A 1 199 ? -7.032  2.837   -15.125 1.00 47.08  ? 199 THR A CG2 1 
ATOM   1604  N N   . HIS A 1 200 ? -10.567 -0.115  -16.061 1.00 35.93  ? 200 HIS A N   1 
ATOM   1605  C CA  . HIS A 1 200 ? -11.523 -1.042  -16.643 1.00 37.99  ? 200 HIS A CA  1 
ATOM   1606  C C   . HIS A 1 200 ? -12.644 -0.265  -17.331 1.00 41.31  ? 200 HIS A C   1 
ATOM   1607  O O   . HIS A 1 200 ? -13.059 0.773   -16.856 1.00 44.87  ? 200 HIS A O   1 
ATOM   1608  C CB  . HIS A 1 200 ? -11.985 -2.002  -15.545 1.00 40.56  ? 200 HIS A CB  1 
ATOM   1609  C CG  . HIS A 1 200 ? -10.824 -2.788  -15.073 1.00 39.33  ? 200 HIS A CG  1 
ATOM   1610  N ND1 . HIS A 1 200 ? -10.344 -3.831  -15.823 1.00 39.45  ? 200 HIS A ND1 1 
ATOM   1611  C CD2 . HIS A 1 200 ? -10.003 -2.662  -14.044 1.00 41.75  ? 200 HIS A CD2 1 
ATOM   1612  C CE1 . HIS A 1 200 ? -9.275  -4.326  -15.218 1.00 43.34  ? 200 HIS A CE1 1 
ATOM   1613  N NE2 . HIS A 1 200 ? -9.050  -3.642  -14.128 1.00 37.54  ? 200 HIS A NE2 1 
ATOM   1614  N N   . ILE A 1 201 ? -13.119 -0.787  -18.461 1.00 43.61  ? 201 ILE A N   1 
ATOM   1615  C CA  . ILE A 1 201 ? -14.108 -0.145  -19.301 1.00 39.50  ? 201 ILE A CA  1 
ATOM   1616  C C   . ILE A 1 201 ? -15.296 -1.093  -19.381 1.00 41.44  ? 201 ILE A C   1 
ATOM   1617  O O   . ILE A 1 201 ? -15.126 -2.254  -19.691 1.00 49.13  ? 201 ILE A O   1 
ATOM   1618  C CB  . ILE A 1 201 ? -13.512 0.159   -20.692 1.00 41.26  ? 201 ILE A CB  1 
ATOM   1619  C CG1 . ILE A 1 201 ? -12.278 1.056   -20.579 1.00 42.23  ? 201 ILE A CG1 1 
ATOM   1620  C CG2 . ILE A 1 201 ? -14.562 0.735   -21.653 1.00 37.41  ? 201 ILE A CG2 1 
ATOM   1621  C CD1 . ILE A 1 201 ? -11.397 1.054   -21.815 1.00 42.98  ? 201 ILE A CD1 1 
ATOM   1622  N N   . ALA A 1 202 ? -16.498 -0.578  -19.136 1.00 46.28  ? 202 ALA A N   1 
ATOM   1623  C CA  . ALA A 1 202 ? -17.702 -1.394  -19.104 1.00 46.75  ? 202 ALA A CA  1 
ATOM   1624  C C   . ALA A 1 202 ? -18.153 -1.750  -20.518 1.00 39.72  ? 202 ALA A C   1 
ATOM   1625  O O   . ALA A 1 202 ? -17.883 -1.018  -21.468 1.00 39.58  ? 202 ALA A O   1 
ATOM   1626  C CB  . ALA A 1 202 ? -18.809 -0.650  -18.383 1.00 50.60  ? 202 ALA A CB  1 
ATOM   1627  N N   . PRO A 1 203 ? -18.919 -2.854  -20.675 1.00 43.30  ? 203 PRO A N   1 
ATOM   1628  C CA  . PRO A 1 203 ? -19.561 -3.181  -21.950 1.00 47.26  ? 203 PRO A CA  1 
ATOM   1629  C C   . PRO A 1 203 ? -20.376 -1.993  -22.431 1.00 47.17  ? 203 PRO A C   1 
ATOM   1630  O O   . PRO A 1 203 ? -20.863 -1.207  -21.630 1.00 51.29  ? 203 PRO A O   1 
ATOM   1631  C CB  . PRO A 1 203 ? -20.493 -4.351  -21.643 1.00 48.56  ? 203 PRO A CB  1 
ATOM   1632  C CG  . PRO A 1 203 ? -19.917 -4.968  -20.365 1.00 53.59  ? 203 PRO A CG  1 
ATOM   1633  C CD  . PRO A 1 203 ? -19.186 -3.859  -19.634 1.00 44.17  ? 203 PRO A CD  1 
ATOM   1634  N N   . ASP A 1 204 ? -20.453 -1.834  -23.741 1.00 48.50  ? 204 ASP A N   1 
ATOM   1635  C CA  . ASP A 1 204 ? -21.322 -0.837  -24.341 1.00 53.95  ? 204 ASP A CA  1 
ATOM   1636  C C   . ASP A 1 204 ? -22.569 -1.597  -24.790 1.00 50.08  ? 204 ASP A C   1 
ATOM   1637  O O   . ASP A 1 204 ? -22.425 -2.531  -25.560 1.00 49.98  ? 204 ASP A O   1 
ATOM   1638  C CB  . ASP A 1 204 ? -20.569 -0.081  -25.442 1.00 55.57  ? 204 ASP A CB  1 
ATOM   1639  C CG  . ASP A 1 204 ? -21.385 0.975   -26.178 1.00 65.49  ? 204 ASP A CG  1 
ATOM   1640  O OD1 . ASP A 1 204 ? -22.646 0.972   -26.039 1.00 62.49  ? 204 ASP A OD1 1 
ATOM   1641  O OD2 . ASP A 1 204 ? -20.752 1.799   -26.884 1.00 55.95  ? 204 ASP A OD2 1 
ATOM   1642  N N   . PRO A 1 205 ? -23.791 -1.289  -24.276 1.00 51.89  ? 205 PRO A N   1 
ATOM   1643  C CA  . PRO A 1 205 ? -25.000 -2.043  -24.629 1.00 51.77  ? 205 PRO A CA  1 
ATOM   1644  C C   . PRO A 1 205 ? -25.450 -1.904  -26.084 1.00 51.63  ? 205 PRO A C   1 
ATOM   1645  O O   . PRO A 1 205 ? -26.241 -2.718  -26.547 1.00 57.00  ? 205 PRO A O   1 
ATOM   1646  C CB  . PRO A 1 205 ? -26.110 -1.515  -23.686 1.00 53.10  ? 205 PRO A CB  1 
ATOM   1647  C CG  . PRO A 1 205 ? -25.366 -0.714  -22.620 1.00 52.95  ? 205 PRO A CG  1 
ATOM   1648  C CD  . PRO A 1 205 ? -24.087 -0.230  -23.287 1.00 53.38  ? 205 PRO A CD  1 
ATOM   1649  N N   . ASN A 1 206 ? -24.898 -0.942  -26.828 1.00 44.75  ? 206 ASN A N   1 
ATOM   1650  C CA  . ASN A 1 206 ? -25.341 -0.701  -28.194 1.00 54.73  ? 206 ASN A CA  1 
ATOM   1651  C C   . ASN A 1 206 ? -24.355 -1.254  -29.226 1.00 60.27  ? 206 ASN A C   1 
ATOM   1652  O O   . ASN A 1 206 ? -24.592 -1.112  -30.422 1.00 57.26  ? 206 ASN A O   1 
ATOM   1653  C CB  . ASN A 1 206 ? -25.614 0.795   -28.421 1.00 54.07  ? 206 ASN A CB  1 
ATOM   1654  C CG  . ASN A 1 206 ? -26.749 1.273   -27.534 1.00 57.67  ? 206 ASN A CG  1 
ATOM   1655  O OD1 . ASN A 1 206 ? -27.871 0.785   -27.656 1.00 55.57  ? 206 ASN A OD1 1 
ATOM   1656  N ND2 . ASN A 1 206 ? -26.462 2.156   -26.588 1.00 59.86  ? 206 ASN A ND2 1 
ATOM   1657  N N   . LEU A 1 207 ? -23.256 -1.883  -28.791 1.00 54.56  ? 207 LEU A N   1 
ATOM   1658  C CA  . LEU A 1 207 ? -22.358 -2.514  -29.752 1.00 51.85  ? 207 LEU A CA  1 
ATOM   1659  C C   . LEU A 1 207 ? -22.634 -4.008  -29.829 1.00 42.47  ? 207 LEU A C   1 
ATOM   1660  O O   . LEU A 1 207 ? -23.187 -4.604  -28.904 1.00 40.04  ? 207 LEU A O   1 
ATOM   1661  C CB  . LEU A 1 207 ? -20.907 -2.283  -29.337 1.00 52.89  ? 207 LEU A CB  1 
ATOM   1662  C CG  . LEU A 1 207 ? -20.412 -0.848  -29.413 1.00 55.82  ? 207 LEU A CG  1 
ATOM   1663  C CD1 . LEU A 1 207 ? -18.990 -0.763  -28.869 1.00 60.26  ? 207 LEU A CD1 1 
ATOM   1664  C CD2 . LEU A 1 207 ? -20.475 -0.346  -30.845 1.00 53.21  ? 207 LEU A CD2 1 
ATOM   1665  N N   . ASP A 1 208 ? -22.219 -4.587  -30.960 1.00 45.52  ? 208 ASP A N   1 
ATOM   1666  C CA  . ASP A 1 208 ? -22.182 -6.029  -31.165 1.00 42.88  ? 208 ASP A CA  1 
ATOM   1667  C C   . ASP A 1 208 ? -21.025 -6.659  -30.365 1.00 42.66  ? 208 ASP A C   1 
ATOM   1668  O O   . ASP A 1 208 ? -20.224 -5.962  -29.778 1.00 44.35  ? 208 ASP A O   1 
ATOM   1669  C CB  . ASP A 1 208 ? -22.064 -6.310  -32.667 1.00 41.41  ? 208 ASP A CB  1 
ATOM   1670  C CG  . ASP A 1 208 ? -20.907 -5.603  -33.351 1.00 47.99  ? 208 ASP A CG  1 
ATOM   1671  O OD1 . ASP A 1 208 ? -21.000 -4.372  -33.489 1.00 56.33  ? 208 ASP A OD1 1 
ATOM   1672  O OD2 . ASP A 1 208 ? -19.913 -6.281  -33.744 1.00 46.89  ? 208 ASP A OD2 1 
ATOM   1673  N N   . TRP A 1 209 ? -20.890 -7.983  -30.441 1.00 42.56  ? 209 TRP A N   1 
ATOM   1674  C CA  . TRP A 1 209 ? -20.063 -8.784  -29.551 1.00 41.59  ? 209 TRP A CA  1 
ATOM   1675  C C   . TRP A 1 209 ? -18.566 -8.494  -29.754 1.00 41.31  ? 209 TRP A C   1 
ATOM   1676  O O   . TRP A 1 209 ? -17.819 -8.208  -28.824 1.00 37.55  ? 209 TRP A O   1 
ATOM   1677  C CB  . TRP A 1 209 ? -20.426 -10.246 -29.833 1.00 39.02  ? 209 TRP A CB  1 
ATOM   1678  C CG  . TRP A 1 209 ? -19.868 -11.294 -28.918 1.00 37.89  ? 209 TRP A CG  1 
ATOM   1679  C CD1 . TRP A 1 209 ? -20.197 -11.536 -27.618 1.00 39.00  ? 209 TRP A CD1 1 
ATOM   1680  C CD2 . TRP A 1 209 ? -18.934 -12.315 -29.283 1.00 33.54  ? 209 TRP A CD2 1 
ATOM   1681  N NE1 . TRP A 1 209 ? -19.485 -12.605 -27.141 1.00 40.25  ? 209 TRP A NE1 1 
ATOM   1682  C CE2 . TRP A 1 209 ? -18.715 -13.108 -28.145 1.00 37.24  ? 209 TRP A CE2 1 
ATOM   1683  C CE3 . TRP A 1 209 ? -18.249 -12.620 -30.454 1.00 35.59  ? 209 TRP A CE3 1 
ATOM   1684  C CZ2 . TRP A 1 209 ? -17.864 -14.209 -28.159 1.00 38.04  ? 209 TRP A CZ2 1 
ATOM   1685  C CZ3 . TRP A 1 209 ? -17.396 -13.696 -30.464 1.00 37.74  ? 209 TRP A CZ3 1 
ATOM   1686  C CH2 . TRP A 1 209 ? -17.204 -14.476 -29.329 1.00 37.44  ? 209 TRP A CH2 1 
ATOM   1687  N N   . SER A 1 210 ? -18.139 -8.551  -31.000 1.00 39.23  ? 210 SER A N   1 
ATOM   1688  C CA  . SER A 1 210 ? -16.743 -8.420  -31.352 1.00 38.77  ? 210 SER A CA  1 
ATOM   1689  C C   . SER A 1 210 ? -16.280 -7.017  -31.028 1.00 48.17  ? 210 SER A C   1 
ATOM   1690  O O   . SER A 1 210 ? -15.154 -6.801  -30.572 1.00 43.38  ? 210 SER A O   1 
ATOM   1691  C CB  . SER A 1 210 ? -16.571 -8.657  -32.820 1.00 38.83  ? 210 SER A CB  1 
ATOM   1692  O OG  . SER A 1 210 ? -17.061 -9.929  -33.160 1.00 46.89  ? 210 SER A OG  1 
ATOM   1693  N N   . ALA A 1 211 ? -17.148 -6.075  -31.389 1.00 48.82  ? 211 ALA A N   1 
ATOM   1694  C CA  . ALA A 1 211 ? -16.814 -4.669  -31.296 1.00 53.33  ? 211 ALA A CA  1 
ATOM   1695  C C   . ALA A 1 211 ? -16.750 -4.288  -29.822 1.00 42.68  ? 211 ALA A C   1 
ATOM   1696  O O   . ALA A 1 211 ? -15.947 -3.455  -29.445 1.00 48.09  ? 211 ALA A O   1 
ATOM   1697  C CB  . ALA A 1 211 ? -17.835 -3.845  -32.055 1.00 51.71  ? 211 ALA A CB  1 
ATOM   1698  N N   . ASN A 1 212 ? -17.579 -4.931  -28.999 1.00 39.72  ? 212 ASN A N   1 
ATOM   1699  C CA  . ASN A 1 212 ? -17.518 -4.701  -27.578 1.00 36.57  ? 212 ASN A CA  1 
ATOM   1700  C C   . ASN A 1 212 ? -16.175 -5.177  -27.026 1.00 34.78  ? 212 ASN A C   1 
ATOM   1701  O O   . ASN A 1 212 ? -15.625 -4.525  -26.149 1.00 38.94  ? 212 ASN A O   1 
ATOM   1702  C CB  . ASN A 1 212 ? -18.629 -5.399  -26.809 1.00 41.51  ? 212 ASN A CB  1 
ATOM   1703  C CG  . ASN A 1 212 ? -19.512 -4.436  -26.059 1.00 42.24  ? 212 ASN A CG  1 
ATOM   1704  O OD1 . ASN A 1 212 ? -19.047 -3.414  -25.568 1.00 44.31  ? 212 ASN A OD1 1 
ATOM   1705  N ND2 . ASN A 1 212 ? -20.804 -4.711  -26.040 1.00 43.70  ? 212 ASN A ND2 1 
ATOM   1706  N N   . LEU A 1 213 ? -15.651 -6.318  -27.491 1.00 34.21  ? 213 LEU A N   1 
ATOM   1707  C CA  . LEU A 1 213 ? -14.330 -6.723  -27.028 1.00 38.29  ? 213 LEU A CA  1 
ATOM   1708  C C   . LEU A 1 213 ? -13.314 -5.617  -27.301 1.00 36.93  ? 213 LEU A C   1 
ATOM   1709  O O   . LEU A 1 213 ? -12.555 -5.236  -26.421 1.00 43.42  ? 213 LEU A O   1 
ATOM   1710  C CB  . LEU A 1 213 ? -13.907 -8.044  -27.659 1.00 38.97  ? 213 LEU A CB  1 
ATOM   1711  C CG  . LEU A 1 213 ? -12.506 -8.539  -27.285 1.00 43.74  ? 213 LEU A CG  1 
ATOM   1712  C CD1 . LEU A 1 213 ? -12.269 -8.554  -25.786 1.00 38.33  ? 213 LEU A CD1 1 
ATOM   1713  C CD2 . LEU A 1 213 ? -12.288 -9.931  -27.854 1.00 50.87  ? 213 LEU A CD2 1 
ATOM   1714  N N   . ALA A 1 214 ? -13.364 -5.032  -28.492 1.00 35.68  ? 214 ALA A N   1 
ATOM   1715  C CA  . ALA A 1 214 ? -12.397 -4.017  -28.863 1.00 36.79  ? 214 ALA A CA  1 
ATOM   1716  C C   . ALA A 1 214 ? -12.541 -2.799  -27.963 1.00 37.37  ? 214 ALA A C   1 
ATOM   1717  O O   . ALA A 1 214 ? -11.551 -2.259  -27.476 1.00 39.37  ? 214 ALA A O   1 
ATOM   1718  C CB  . ALA A 1 214 ? -12.570 -3.653  -30.310 1.00 34.75  ? 214 ALA A CB  1 
ATOM   1719  N N   . HIS A 1 215 ? -13.792 -2.397  -27.770 1.00 37.98  ? 215 HIS A N   1 
ATOM   1720  C CA  . HIS A 1 215 ? -14.184 -1.276  -26.938 1.00 33.15  ? 215 HIS A CA  1 
ATOM   1721  C C   . HIS A 1 215 ? -13.646 -1.451  -25.531 1.00 33.04  ? 215 HIS A C   1 
ATOM   1722  O O   . HIS A 1 215 ? -13.099 -0.512  -24.959 1.00 37.81  ? 215 HIS A O   1 
ATOM   1723  C CB  . HIS A 1 215 ? -15.716 -1.163  -26.873 1.00 35.93  ? 215 HIS A CB  1 
ATOM   1724  C CG  . HIS A 1 215 ? -16.201 -0.084  -25.955 1.00 33.95  ? 215 HIS A CG  1 
ATOM   1725  N ND1 . HIS A 1 215 ? -15.920 1.256   -26.154 1.00 42.35  ? 215 HIS A ND1 1 
ATOM   1726  C CD2 . HIS A 1 215 ? -16.872 -0.146  -24.820 1.00 34.57  ? 215 HIS A CD2 1 
ATOM   1727  C CE1 . HIS A 1 215 ? -16.403 1.970   -25.132 1.00 38.14  ? 215 HIS A CE1 1 
ATOM   1728  N NE2 . HIS A 1 215 ? -17.037 1.143   -24.350 1.00 39.86  ? 215 HIS A NE2 1 
ATOM   1729  N N   . MET A 1 216 ? -13.846 -2.641  -24.968 1.00 38.54  ? 216 MET A N   1 
ATOM   1730  C CA  . MET A 1 216 ? -13.465 -2.915  -23.589 1.00 34.49  ? 216 MET A CA  1 
ATOM   1731  C C   . MET A 1 216 ? -11.944 -3.068  -23.473 1.00 37.58  ? 216 MET A C   1 
ATOM   1732  O O   . MET A 1 216 ? -11.392 -2.968  -22.391 1.00 36.68  ? 216 MET A O   1 
ATOM   1733  C CB  . MET A 1 216 ? -14.181 -4.177  -23.102 1.00 33.52  ? 216 MET A CB  1 
ATOM   1734  C CG  . MET A 1 216 ? -15.664 -3.935  -22.767 1.00 35.35  ? 216 MET A CG  1 
ATOM   1735  S SD  . MET A 1 216 ? -16.485 -5.347  -21.961 1.00 42.53  ? 216 MET A SD  1 
ATOM   1736  C CE  . MET A 1 216 ? -16.421 -6.561  -23.281 1.00 38.00  ? 216 MET A CE  1 
ATOM   1737  N N   . MET A 1 217 ? -11.240 -3.251  -24.597 1.00 36.34  ? 217 MET A N   1 
ATOM   1738  C CA  . MET A 1 217 ? -9.785  -3.302  -24.566 1.00 34.82  ? 217 MET A CA  1 
ATOM   1739  C C   . MET A 1 217 ? -9.197  -1.893  -24.646 1.00 39.84  ? 217 MET A C   1 
ATOM   1740  O O   . MET A 1 217 ? -8.031  -1.650  -24.279 1.00 33.14  ? 217 MET A O   1 
ATOM   1741  C CB  . MET A 1 217 ? -9.292  -4.183  -25.717 1.00 39.99  ? 217 MET A CB  1 
ATOM   1742  C CG  . MET A 1 217 ? -9.331  -5.659  -25.359 1.00 39.88  ? 217 MET A CG  1 
ATOM   1743  S SD  . MET A 1 217 ? -9.086  -6.732  -26.763 1.00 43.21  ? 217 MET A SD  1 
ATOM   1744  C CE  . MET A 1 217 ? -7.319  -6.567  -26.993 1.00 47.06  ? 217 MET A CE  1 
ATOM   1745  N N   . GLY A 1 218 ? -10.036 -0.945  -25.088 1.00 38.79  ? 218 GLY A N   1 
ATOM   1746  C CA  . GLY A 1 218 ? -9.620  0.433   -25.241 1.00 39.92  ? 218 GLY A CA  1 
ATOM   1747  C C   . GLY A 1 218 ? -9.470  0.865   -26.695 1.00 44.22  ? 218 GLY A C   1 
ATOM   1748  O O   . GLY A 1 218 ? -8.798  1.862   -26.933 1.00 43.25  ? 218 GLY A O   1 
ATOM   1749  N N   . PHE A 1 219 ? -10.067 0.133   -27.659 1.00 51.13  ? 219 PHE A N   1 
ATOM   1750  C CA  . PHE A 1 219 ? -9.958  0.481   -29.084 1.00 46.19  ? 219 PHE A CA  1 
ATOM   1751  C C   . PHE A 1 219 ? -11.350 0.750   -29.622 1.00 50.90  ? 219 PHE A C   1 
ATOM   1752  O O   . PHE A 1 219 ? -12.146 -0.205  -29.650 1.00 46.82  ? 219 PHE A O   1 
ATOM   1753  C CB  . PHE A 1 219 ? -9.335  -0.636  -29.931 1.00 43.22  ? 219 PHE A CB  1 
ATOM   1754  C CG  . PHE A 1 219 ? -7.944  -0.973  -29.484 1.00 42.84  ? 219 PHE A CG  1 
ATOM   1755  C CD1 . PHE A 1 219 ? -7.745  -1.742  -28.343 1.00 48.37  ? 219 PHE A CD1 1 
ATOM   1756  C CD2 . PHE A 1 219 ? -6.843  -0.367  -30.060 1.00 44.02  ? 219 PHE A CD2 1 
ATOM   1757  C CE1 . PHE A 1 219 ? -6.472  -1.991  -27.858 1.00 38.57  ? 219 PHE A CE1 1 
ATOM   1758  C CE2 . PHE A 1 219 ? -5.559  -0.628  -29.580 1.00 46.16  ? 219 PHE A CE2 1 
ATOM   1759  C CZ  . PHE A 1 219 ? -5.377  -1.430  -28.473 1.00 39.20  ? 219 PHE A CZ  1 
ATOM   1760  N N   . ASP A 1 220 ? -11.604 2.015   -30.053 1.00 45.17  ? 220 ASP A N   1 
ATOM   1761  C CA  . ASP A 1 220 ? -12.929 2.418   -30.533 1.00 52.54  ? 220 ASP A CA  1 
ATOM   1762  C C   . ASP A 1 220 ? -12.997 2.817   -32.008 1.00 45.55  ? 220 ASP A C   1 
ATOM   1763  O O   . ASP A 1 220 ? -14.081 3.167   -32.455 1.00 45.37  ? 220 ASP A O   1 
ATOM   1764  C CB  . ASP A 1 220 ? -13.534 3.529   -29.666 1.00 52.84  ? 220 ASP A CB  1 
ATOM   1765  C CG  . ASP A 1 220 ? -13.905 2.969   -28.315 1.00 54.28  ? 220 ASP A CG  1 
ATOM   1766  O OD1 . ASP A 1 220 ? -14.773 2.055   -28.271 1.00 60.52  ? 220 ASP A OD1 1 
ATOM   1767  O OD2 . ASP A 1 220 ? -13.267 3.379   -27.341 1.00 57.10  ? 220 ASP A OD2 1 
ATOM   1768  N N   . ASP A 1 221 ? -11.922 2.674   -32.794 1.00 45.04  ? 221 ASP A N   1 
ATOM   1769  C CA  . ASP A 1 221 ? -11.977 3.051   -34.203 1.00 47.95  ? 221 ASP A CA  1 
ATOM   1770  C C   . ASP A 1 221 ? -12.793 2.026   -34.988 1.00 52.00  ? 221 ASP A C   1 
ATOM   1771  O O   . ASP A 1 221 ? -12.718 0.816   -34.760 1.00 54.94  ? 221 ASP A O   1 
ATOM   1772  C CB  . ASP A 1 221 ? -10.583 3.252   -34.816 1.00 56.38  ? 221 ASP A CB  1 
ATOM   1773  C CG  . ASP A 1 221 ? -9.888  4.544   -34.375 1.00 67.41  ? 221 ASP A CG  1 
ATOM   1774  O OD1 . ASP A 1 221 ? -10.567 5.456   -33.844 1.00 66.79  ? 221 ASP A OD1 1 
ATOM   1775  O OD2 . ASP A 1 221 ? -8.660  4.622   -34.508 1.00 71.95  ? 221 ASP A OD2 1 
ATOM   1776  N N   . PHE A 1 222 ? -13.542 2.529   -35.964 1.00 51.16  ? 222 PHE A N   1 
ATOM   1777  C CA  . PHE A 1 222 ? -14.427 1.710   -36.758 1.00 50.04  ? 222 PHE A CA  1 
ATOM   1778  C C   . PHE A 1 222 ? -13.661 0.581   -37.441 1.00 44.07  ? 222 PHE A C   1 
ATOM   1779  O O   . PHE A 1 222 ? -14.184 -0.513  -37.512 1.00 44.15  ? 222 PHE A O   1 
ATOM   1780  C CB  . PHE A 1 222 ? -15.156 2.560   -37.795 1.00 63.83  ? 222 PHE A CB  1 
ATOM   1781  C CG  . PHE A 1 222 ? -15.946 1.761   -38.805 1.00 67.61  ? 222 PHE A CG  1 
ATOM   1782  C CD1 . PHE A 1 222 ? -17.162 1.187   -38.454 1.00 66.63  ? 222 PHE A CD1 1 
ATOM   1783  C CD2 . PHE A 1 222 ? -15.445 1.544   -40.090 1.00 69.62  ? 222 PHE A CD2 1 
ATOM   1784  C CE1 . PHE A 1 222 ? -17.872 0.442   -39.387 1.00 63.93  ? 222 PHE A CE1 1 
ATOM   1785  C CE2 . PHE A 1 222 ? -16.152 0.786   -41.014 1.00 63.23  ? 222 PHE A CE2 1 
ATOM   1786  C CZ  . PHE A 1 222 ? -17.369 0.252   -40.660 1.00 60.87  ? 222 PHE A CZ  1 
ATOM   1787  N N   . GLU A 1 223 ? -12.458 0.845   -37.967 1.00 51.05  ? 223 GLU A N   1 
ATOM   1788  C CA  . GLU A 1 223 ? -11.695 -0.161  -38.695 1.00 49.19  ? 223 GLU A CA  1 
ATOM   1789  C C   . GLU A 1 223 ? -11.278 -1.300  -37.768 1.00 50.09  ? 223 GLU A C   1 
ATOM   1790  O O   . GLU A 1 223 ? -11.038 -2.396  -38.255 1.00 49.82  ? 223 GLU A O   1 
ATOM   1791  C CB  . GLU A 1 223 ? -10.421 0.409   -39.328 1.00 60.24  ? 223 GLU A CB  1 
ATOM   1792  C CG  . GLU A 1 223 ? -10.633 1.259   -40.581 1.00 76.95  ? 223 GLU A CG  1 
ATOM   1793  C CD  . GLU A 1 223 ? -9.367  1.709   -41.314 1.00 95.20  ? 223 GLU A CD  1 
ATOM   1794  O OE1 . GLU A 1 223 ? -9.487  2.491   -42.288 1.00 100.57 ? 223 GLU A OE1 1 
ATOM   1795  O OE2 . GLU A 1 223 ? -8.249  1.261   -40.943 1.00 96.84  ? 223 GLU A OE2 1 
ATOM   1796  N N   . VAL A 1 224 ? -11.120 -1.022  -36.461 1.00 43.95  ? 224 VAL A N   1 
ATOM   1797  C CA  . VAL A 1 224 ? -10.728 -2.039  -35.495 1.00 45.13  ? 224 VAL A CA  1 
ATOM   1798  C C   . VAL A 1 224 ? -11.934 -2.922  -35.196 1.00 43.52  ? 224 VAL A C   1 
ATOM   1799  O O   . VAL A 1 224 ? -11.807 -4.154  -35.179 1.00 44.42  ? 224 VAL A O   1 
ATOM   1800  C CB  . VAL A 1 224 ? -10.132 -1.449  -34.198 1.00 45.85  ? 224 VAL A CB  1 
ATOM   1801  C CG1 . VAL A 1 224 ? -9.883  -2.531  -33.169 1.00 50.40  ? 224 VAL A CG1 1 
ATOM   1802  C CG2 . VAL A 1 224 ? -8.856  -0.662  -34.456 1.00 45.72  ? 224 VAL A CG2 1 
ATOM   1803  N N   . TYR A 1 225 ? -13.094 -2.294  -34.956 1.00 42.19  ? 225 TYR A N   1 
ATOM   1804  C CA  . TYR A 1 225 ? -14.342 -3.037  -34.842 1.00 42.37  ? 225 TYR A CA  1 
ATOM   1805  C C   . TYR A 1 225 ? -14.500 -3.989  -36.026 1.00 40.65  ? 225 TYR A C   1 
ATOM   1806  O O   . TYR A 1 225 ? -14.869 -5.144  -35.878 1.00 39.14  ? 225 TYR A O   1 
ATOM   1807  C CB  . TYR A 1 225 ? -15.543 -2.092  -34.802 1.00 47.66  ? 225 TYR A CB  1 
ATOM   1808  C CG  . TYR A 1 225 ? -15.720 -1.259  -33.553 1.00 49.89  ? 225 TYR A CG  1 
ATOM   1809  C CD1 . TYR A 1 225 ? -14.895 -1.407  -32.454 1.00 49.30  ? 225 TYR A CD1 1 
ATOM   1810  C CD2 . TYR A 1 225 ? -16.726 -0.305  -33.473 1.00 46.98  ? 225 TYR A CD2 1 
ATOM   1811  C CE1 . TYR A 1 225 ? -15.082 -0.653  -31.307 1.00 49.75  ? 225 TYR A CE1 1 
ATOM   1812  C CE2 . TYR A 1 225 ? -16.919 0.458   -32.334 1.00 45.56  ? 225 TYR A CE2 1 
ATOM   1813  C CZ  . TYR A 1 225 ? -16.085 0.290   -31.247 1.00 46.95  ? 225 TYR A CZ  1 
ATOM   1814  O OH  . TYR A 1 225 ? -16.240 1.005   -30.081 1.00 49.95  ? 225 TYR A OH  1 
ATOM   1815  N N   . GLU A 1 226 ? -14.171 -3.505  -37.223 1.00 40.99  ? 226 GLU A N   1 
ATOM   1816  C CA  . GLU A 1 226 ? -14.335 -4.312  -38.415 1.00 41.20  ? 226 GLU A CA  1 
ATOM   1817  C C   . GLU A 1 226 ? -13.329 -5.458  -38.379 1.00 40.76  ? 226 GLU A C   1 
ATOM   1818  O O   . GLU A 1 226 ? -13.654 -6.578  -38.741 1.00 39.43  ? 226 GLU A O   1 
ATOM   1819  C CB  . GLU A 1 226 ? -14.191 -3.417  -39.649 1.00 42.20  ? 226 GLU A CB  1 
ATOM   1820  C CG  . GLU A 1 226 ? -15.455 -2.623  -39.956 1.00 45.08  ? 226 GLU A CG  1 
ATOM   1821  C CD  . GLU A 1 226 ? -16.521 -3.473  -40.634 1.00 48.47  ? 226 GLU A CD  1 
ATOM   1822  O OE1 . GLU A 1 226 ? -17.482 -3.890  -39.935 1.00 48.08  ? 226 GLU A OE1 1 
ATOM   1823  O OE2 . GLU A 1 226 ? -16.369 -3.744  -41.869 1.00 50.64  ? 226 GLU A OE2 1 
ATOM   1824  N N   . LEU A 1 227 ? -12.086 -5.169  -37.979 1.00 42.93  ? 227 LEU A N   1 
ATOM   1825  C CA  . LEU A 1 227 ? -11.089 -6.216  -37.902 1.00 43.79  ? 227 LEU A CA  1 
ATOM   1826  C C   . LEU A 1 227 ? -11.553 -7.297  -36.933 1.00 44.34  ? 227 LEU A C   1 
ATOM   1827  O O   . LEU A 1 227 ? -11.422 -8.463  -37.235 1.00 41.87  ? 227 LEU A O   1 
ATOM   1828  C CB  . LEU A 1 227 ? -9.745  -5.653  -37.441 1.00 46.10  ? 227 LEU A CB  1 
ATOM   1829  C CG  . LEU A 1 227 ? -8.680  -6.717  -37.149 1.00 43.51  ? 227 LEU A CG  1 
ATOM   1830  C CD1 . LEU A 1 227 ? -8.436  -7.577  -38.366 1.00 45.67  ? 227 LEU A CD1 1 
ATOM   1831  C CD2 . LEU A 1 227 ? -7.366  -6.096  -36.690 1.00 45.30  ? 227 LEU A CD2 1 
ATOM   1832  N N   . PHE A 1 228 ? -12.069 -6.908  -35.765 1.00 41.26  ? 228 PHE A N   1 
ATOM   1833  C CA  . PHE A 1 228 ? -12.378 -7.882  -34.736 1.00 40.28  ? 228 PHE A CA  1 
ATOM   1834  C C   . PHE A 1 228 ? -13.500 -8.755  -35.224 1.00 39.84  ? 228 PHE A C   1 
ATOM   1835  O O   . PHE A 1 228 ? -13.521 -9.931  -34.912 1.00 40.03  ? 228 PHE A O   1 
ATOM   1836  C CB  . PHE A 1 228 ? -12.765 -7.236  -33.402 1.00 38.93  ? 228 PHE A CB  1 
ATOM   1837  C CG  . PHE A 1 228 ? -11.593 -6.958  -32.515 1.00 37.11  ? 228 PHE A CG  1 
ATOM   1838  C CD1 . PHE A 1 228 ? -10.436 -6.401  -33.020 1.00 40.54  ? 228 PHE A CD1 1 
ATOM   1839  C CD2 . PHE A 1 228 ? -11.643 -7.259  -31.165 1.00 41.74  ? 228 PHE A CD2 1 
ATOM   1840  C CE1 . PHE A 1 228 ? -9.359  -6.140  -32.186 1.00 43.82  ? 228 PHE A CE1 1 
ATOM   1841  C CE2 . PHE A 1 228 ? -10.558 -7.005  -30.339 1.00 34.17  ? 228 PHE A CE2 1 
ATOM   1842  C CZ  . PHE A 1 228 ? -9.433  -6.444  -30.843 1.00 37.14  ? 228 PHE A CZ  1 
ATOM   1843  N N   . ARG A 1 229 ? -14.434 -8.141  -35.953 1.00 46.21  ? 229 ARG A N   1 
ATOM   1844  C CA  . ARG A 1 229 ? -15.544 -8.878  -36.537 1.00 47.31  ? 229 ARG A CA  1 
ATOM   1845  C C   . ARG A 1 229 ? -14.979 -9.972  -37.450 1.00 45.66  ? 229 ARG A C   1 
ATOM   1846  O O   . ARG A 1 229 ? -15.345 -11.136 -37.298 1.00 43.98  ? 229 ARG A O   1 
ATOM   1847  C CB  . ARG A 1 229 ? -16.511 -7.926  -37.252 1.00 44.35  ? 229 ARG A CB  1 
ATOM   1848  C CG  . ARG A 1 229 ? -17.478 -7.184  -36.337 1.00 42.91  ? 229 ARG A CG  1 
ATOM   1849  C CD  . ARG A 1 229 ? -17.907 -5.835  -36.932 1.00 43.84  ? 229 ARG A CD  1 
ATOM   1850  N NE  . ARG A 1 229 ? -18.607 -4.970  -35.997 1.00 38.62  ? 229 ARG A NE  1 
ATOM   1851  C CZ  . ARG A 1 229 ? -18.716 -3.651  -36.130 1.00 37.18  ? 229 ARG A CZ  1 
ATOM   1852  N NH1 . ARG A 1 229 ? -18.235 -3.043  -37.194 1.00 41.38  ? 229 ARG A NH1 1 
ATOM   1853  N NH2 . ARG A 1 229 ? -19.321 -2.933  -35.208 1.00 35.76  ? 229 ARG A NH2 1 
ATOM   1854  N N   . LEU A 1 230 ? -14.086 -9.593  -38.385 1.00 45.43  ? 230 LEU A N   1 
ATOM   1855  C CA  . LEU A 1 230 ? -13.515 -10.538 -39.340 1.00 43.28  ? 230 LEU A CA  1 
ATOM   1856  C C   . LEU A 1 230 ? -12.712 -11.607 -38.600 1.00 44.18  ? 230 LEU A C   1 
ATOM   1857  O O   . LEU A 1 230 ? -12.873 -12.811 -38.833 1.00 45.83  ? 230 LEU A O   1 
ATOM   1858  C CB  . LEU A 1 230 ? -12.628 -9.796  -40.348 1.00 44.19  ? 230 LEU A CB  1 
ATOM   1859  C CG  . LEU A 1 230 ? -11.875 -10.686 -41.341 1.00 45.65  ? 230 LEU A CG  1 
ATOM   1860  C CD1 . LEU A 1 230 ? -12.838 -11.484 -42.187 1.00 45.71  ? 230 LEU A CD1 1 
ATOM   1861  C CD2 . LEU A 1 230 ? -10.950 -9.895  -42.245 1.00 45.58  ? 230 LEU A CD2 1 
ATOM   1862  N N   . TYR A 1 231 ? -11.852 -11.154 -37.685 1.00 42.57  ? 231 TYR A N   1 
ATOM   1863  C CA  . TYR A 1 231 ? -10.989 -12.041 -36.926 1.00 44.39  ? 231 TYR A CA  1 
ATOM   1864  C C   . TYR A 1 231 ? -11.830 -13.114 -36.224 1.00 40.31  ? 231 TYR A C   1 
ATOM   1865  O O   . TYR A 1 231 ? -11.522 -14.299 -36.310 1.00 44.45  ? 231 TYR A O   1 
ATOM   1866  C CB  . TYR A 1 231 ? -10.073 -11.235 -35.986 1.00 50.23  ? 231 TYR A CB  1 
ATOM   1867  C CG  . TYR A 1 231 ? -9.122  -12.092 -35.187 1.00 48.91  ? 231 TYR A CG  1 
ATOM   1868  C CD1 . TYR A 1 231 ? -9.599  -12.877 -34.151 1.00 50.98  ? 231 TYR A CD1 1 
ATOM   1869  C CD2 . TYR A 1 231 ? -7.777  -12.192 -35.509 1.00 48.84  ? 231 TYR A CD2 1 
ATOM   1870  C CE1 . TYR A 1 231 ? -8.755  -13.706 -33.433 1.00 58.34  ? 231 TYR A CE1 1 
ATOM   1871  C CE2 . TYR A 1 231 ? -6.919  -13.039 -34.813 1.00 49.51  ? 231 TYR A CE2 1 
ATOM   1872  C CZ  . TYR A 1 231 ? -7.416  -13.787 -33.762 1.00 50.50  ? 231 TYR A CZ  1 
ATOM   1873  O OH  . TYR A 1 231 ? -6.651  -14.627 -33.008 1.00 57.44  ? 231 TYR A OH  1 
ATOM   1874  N N   . MET A 1 232 ? -12.931 -12.710 -35.586 1.00 39.37  ? 232 MET A N   1 
ATOM   1875  C CA  . MET A 1 232 ? -13.750 -13.630 -34.820 1.00 38.85  ? 232 MET A CA  1 
ATOM   1876  C C   . MET A 1 232 ? -14.492 -14.579 -35.751 1.00 42.78  ? 232 MET A C   1 
ATOM   1877  O O   . MET A 1 232 ? -14.715 -15.741 -35.409 1.00 40.16  ? 232 MET A O   1 
ATOM   1878  C CB  . MET A 1 232 ? -14.755 -12.872 -33.960 1.00 40.46  ? 232 MET A CB  1 
ATOM   1879  C CG  . MET A 1 232 ? -14.075 -12.005 -32.915 1.00 42.24  ? 232 MET A CG  1 
ATOM   1880  S SD  . MET A 1 232 ? -13.406 -13.037 -31.632 1.00 51.90  ? 232 MET A SD  1 
ATOM   1881  C CE  . MET A 1 232 ? -12.115 -11.952 -31.017 1.00 52.79  ? 232 MET A CE  1 
ATOM   1882  N N   . PHE A 1 233 ? -14.881 -14.065 -36.920 1.00 41.76  ? 233 PHE A N   1 
ATOM   1883  C CA  . PHE A 1 233 ? -15.522 -14.878 -37.940 1.00 42.52  ? 233 PHE A CA  1 
ATOM   1884  C C   . PHE A 1 233 ? -14.571 -15.979 -38.407 1.00 36.21  ? 233 PHE A C   1 
ATOM   1885  O O   . PHE A 1 233 ? -14.952 -17.141 -38.443 1.00 45.56  ? 233 PHE A O   1 
ATOM   1886  C CB  . PHE A 1 233 ? -16.020 -13.980 -39.075 1.00 42.64  ? 233 PHE A CB  1 
ATOM   1887  C CG  . PHE A 1 233 ? -16.411 -14.716 -40.323 1.00 41.36  ? 233 PHE A CG  1 
ATOM   1888  C CD1 . PHE A 1 233 ? -17.653 -15.310 -40.436 1.00 44.81  ? 233 PHE A CD1 1 
ATOM   1889  C CD2 . PHE A 1 233 ? -15.515 -14.843 -41.368 1.00 44.00  ? 233 PHE A CD2 1 
ATOM   1890  C CE1 . PHE A 1 233 ? -18.013 -15.977 -41.593 1.00 46.08  ? 233 PHE A CE1 1 
ATOM   1891  C CE2 . PHE A 1 233 ? -15.880 -15.499 -42.535 1.00 44.12  ? 233 PHE A CE2 1 
ATOM   1892  C CZ  . PHE A 1 233 ? -17.123 -16.071 -42.638 1.00 44.75  ? 233 PHE A CZ  1 
ATOM   1893  N N   . LEU A 1 234 ? -13.326 -15.634 -38.729 1.00 37.97  ? 234 LEU A N   1 
ATOM   1894  C CA  . LEU A 1 234 ? -12.402 -16.579 -39.343 1.00 39.35  ? 234 LEU A CA  1 
ATOM   1895  C C   . LEU A 1 234 ? -11.931 -17.675 -38.391 1.00 41.36  ? 234 LEU A C   1 
ATOM   1896  O O   . LEU A 1 234 ? -11.670 -18.800 -38.829 1.00 39.82  ? 234 LEU A O   1 
ATOM   1897  C CB  . LEU A 1 234 ? -11.194 -15.804 -39.871 1.00 41.65  ? 234 LEU A CB  1 
ATOM   1898  C CG  . LEU A 1 234 ? -11.502 -14.756 -40.936 1.00 44.46  ? 234 LEU A CG  1 
ATOM   1899  C CD1 . LEU A 1 234 ? -10.227 -14.097 -41.454 1.00 45.97  ? 234 LEU A CD1 1 
ATOM   1900  C CD2 . LEU A 1 234 ? -12.299 -15.350 -42.089 1.00 47.52  ? 234 LEU A CD2 1 
ATOM   1901  N N   . HIS A 1 235 ? -11.818 -17.369 -37.090 1.00 38.26  ? 235 HIS A N   1 
ATOM   1902  C CA  . HIS A 1 235 ? -11.218 -18.313 -36.157 1.00 37.19  ? 235 HIS A CA  1 
ATOM   1903  C C   . HIS A 1 235 ? -12.262 -19.132 -35.414 1.00 35.35  ? 235 HIS A C   1 
ATOM   1904  O O   . HIS A 1 235 ? -11.915 -19.912 -34.537 1.00 42.13  ? 235 HIS A O   1 
ATOM   1905  C CB  . HIS A 1 235 ? -10.298 -17.599 -35.160 1.00 40.80  ? 235 HIS A CB  1 
ATOM   1906  C CG  . HIS A 1 235 ? -9.115  -16.967 -35.772 1.00 45.68  ? 235 HIS A CG  1 
ATOM   1907  N ND1 . HIS A 1 235 ? -9.160  -15.725 -36.377 1.00 52.59  ? 235 HIS A ND1 1 
ATOM   1908  C CD2 . HIS A 1 235 ? -7.845  -17.384 -35.844 1.00 49.75  ? 235 HIS A CD2 1 
ATOM   1909  C CE1 . HIS A 1 235 ? -7.948  -15.430 -36.837 1.00 48.39  ? 235 HIS A CE1 1 
ATOM   1910  N NE2 . HIS A 1 235 ? -7.136  -16.412 -36.509 1.00 48.28  ? 235 HIS A NE2 1 
ATOM   1911  N N   . SER A 1 236 ? -13.529 -18.928 -35.739 1.00 39.66  ? 236 SER A N   1 
ATOM   1912  C CA  . SER A 1 236 ? -14.662 -19.550 -35.069 1.00 44.36  ? 236 SER A CA  1 
ATOM   1913  C C   . SER A 1 236 ? -14.525 -21.065 -34.915 1.00 49.76  ? 236 SER A C   1 
ATOM   1914  O O   . SER A 1 236 ? -14.830 -21.624 -33.841 1.00 49.75  ? 236 SER A O   1 
ATOM   1915  C CB  . SER A 1 236 ? -15.896 -19.249 -35.873 1.00 47.62  ? 236 SER A CB  1 
ATOM   1916  O OG  . SER A 1 236 ? -15.633 -19.520 -37.244 1.00 43.68  ? 236 SER A OG  1 
ATOM   1917  N N   . ASP A 1 237 ? -14.167 -21.735 -36.024 1.00 46.86  ? 237 ASP A N   1 
ATOM   1918  C CA  . ASP A 1 237 ? -14.279 -23.185 -36.128 1.00 44.38  ? 237 ASP A CA  1 
ATOM   1919  C C   . ASP A 1 237 ? -13.387 -23.721 -37.252 1.00 43.46  ? 237 ASP A C   1 
ATOM   1920  O O   . ASP A 1 237 ? -13.159 -23.059 -38.274 1.00 51.90  ? 237 ASP A O   1 
ATOM   1921  C CB  . ASP A 1 237 ? -15.739 -23.575 -36.355 1.00 46.11  ? 237 ASP A CB  1 
ATOM   1922  C CG  . ASP A 1 237 ? -16.119 -24.962 -35.859 1.00 56.30  ? 237 ASP A CG  1 
ATOM   1923  O OD1 . ASP A 1 237 ? -15.721 -25.323 -34.719 1.00 68.50  ? 237 ASP A OD1 1 
ATOM   1924  O OD2 . ASP A 1 237 ? -16.852 -25.660 -36.601 1.00 59.05  ? 237 ASP A OD2 1 
ATOM   1925  N N   . HIS A 1 238 ? -12.899 -24.942 -37.060 1.00 40.48  ? 238 HIS A N   1 
ATOM   1926  C CA  . HIS A 1 238 ? -12.005 -25.601 -38.002 1.00 40.54  ? 238 HIS A CA  1 
ATOM   1927  C C   . HIS A 1 238 ? -12.069 -27.102 -37.764 1.00 40.27  ? 238 HIS A C   1 
ATOM   1928  O O   . HIS A 1 238 ? -11.086 -27.705 -37.314 1.00 45.18  ? 238 HIS A O   1 
ATOM   1929  C CB  . HIS A 1 238 ? -10.581 -25.076 -37.841 1.00 40.20  ? 238 HIS A CB  1 
ATOM   1930  C CG  . HIS A 1 238 ? -9.779  -25.129 -39.115 1.00 48.60  ? 238 HIS A CG  1 
ATOM   1931  N ND1 . HIS A 1 238 ? -8.610  -25.850 -39.270 1.00 45.52  ? 238 HIS A ND1 1 
ATOM   1932  C CD2 . HIS A 1 238 ? -9.997  -24.508 -40.294 1.00 47.02  ? 238 HIS A CD2 1 
ATOM   1933  C CE1 . HIS A 1 238 ? -8.134  -25.643 -40.488 1.00 50.12  ? 238 HIS A CE1 1 
ATOM   1934  N NE2 . HIS A 1 238 ? -8.954  -24.823 -41.125 1.00 53.09  ? 238 HIS A NE2 1 
ATOM   1935  N N   . GLU A 1 239 ? -13.278 -27.658 -37.912 1.00 46.40  ? 239 GLU A N   1 
ATOM   1936  C CA  . GLU A 1 239 ? -13.525 -29.081 -37.719 1.00 51.96  ? 239 GLU A CA  1 
ATOM   1937  C C   . GLU A 1 239 ? -13.385 -29.443 -36.244 1.00 53.81  ? 239 GLU A C   1 
ATOM   1938  O O   . GLU A 1 239 ? -13.253 -28.573 -35.393 1.00 51.93  ? 239 GLU A O   1 
ATOM   1939  C CB  . GLU A 1 239 ? -12.565 -29.931 -38.553 1.00 49.82  ? 239 GLU A CB  1 
ATOM   1940  C CG  . GLU A 1 239 ? -13.107 -30.310 -39.907 1.00 62.18  ? 239 GLU A CG  1 
ATOM   1941  C CD  . GLU A 1 239 ? -12.275 -31.343 -40.665 1.00 58.24  ? 239 GLU A CD  1 
ATOM   1942  O OE1 . GLU A 1 239 ? -12.648 -31.629 -41.826 1.00 58.41  ? 239 GLU A OE1 1 
ATOM   1943  O OE2 . GLU A 1 239 ? -11.264 -31.864 -40.100 1.00 59.33  ? 239 GLU A OE2 1 
ATOM   1944  N N   . GLY A 1 240 ? -13.416 -30.748 -35.962 1.00 47.97  ? 240 GLY A N   1 
ATOM   1945  C CA  . GLY A 1 240 ? -13.580 -31.223 -34.611 1.00 47.89  ? 240 GLY A CA  1 
ATOM   1946  C C   . GLY A 1 240 ? -12.299 -31.821 -34.054 1.00 46.69  ? 240 GLY A C   1 
ATOM   1947  O O   . GLY A 1 240 ? -12.274 -32.199 -32.883 1.00 51.98  ? 240 GLY A O   1 
ATOM   1948  N N   . GLY A 1 241 ? -11.237 -31.833 -34.867 1.00 39.73  ? 241 GLY A N   1 
ATOM   1949  C CA  . GLY A 1 241 ? -10.054 -32.617 -34.551 1.00 40.49  ? 241 GLY A CA  1 
ATOM   1950  C C   . GLY A 1 241 ? -8.835  -31.825 -34.081 1.00 42.83  ? 241 GLY A C   1 
ATOM   1951  O O   . GLY A 1 241 ? -7.856  -32.410 -33.605 1.00 45.01  ? 241 GLY A O   1 
ATOM   1952  N N   . ASN A 1 242 ? -8.858  -30.492 -34.232 1.00 47.29  ? 242 ASN A N   1 
ATOM   1953  C CA  . ASN A 1 242 ? -7.824  -29.655 -33.636 1.00 44.03  ? 242 ASN A CA  1 
ATOM   1954  C C   . ASN A 1 242 ? -7.898  -29.786 -32.102 1.00 39.73  ? 242 ASN A C   1 
ATOM   1955  O O   . ASN A 1 242 ? -8.934  -30.119 -31.524 1.00 41.90  ? 242 ASN A O   1 
ATOM   1956  C CB  . ASN A 1 242 ? -7.956  -28.205 -34.106 1.00 47.30  ? 242 ASN A CB  1 
ATOM   1957  C CG  . ASN A 1 242 ? -9.186  -27.528 -33.544 1.00 47.21  ? 242 ASN A CG  1 
ATOM   1958  O OD1 . ASN A 1 242 ? -9.281  -27.341 -32.333 1.00 46.52  ? 242 ASN A OD1 1 
ATOM   1959  N ND2 . ASN A 1 242 ? -10.165 -27.234 -34.390 1.00 46.91  ? 242 ASN A ND2 1 
ATOM   1960  N N   . VAL A 1 243 ? -6.784  -29.529 -31.415 1.00 38.90  ? 243 VAL A N   1 
ATOM   1961  C CA  . VAL A 1 243 ? -6.659  -29.905 -30.021 1.00 34.99  ? 243 VAL A CA  1 
ATOM   1962  C C   . VAL A 1 243 ? -7.728  -29.228 -29.155 1.00 35.70  ? 243 VAL A C   1 
ATOM   1963  O O   . VAL A 1 243 ? -8.296  -29.853 -28.272 1.00 33.30  ? 243 VAL A O   1 
ATOM   1964  C CB  . VAL A 1 243 ? -5.238  -29.563 -29.569 1.00 43.96  ? 243 VAL A CB  1 
ATOM   1965  C CG1 . VAL A 1 243 ? -5.130  -29.385 -28.054 1.00 43.18  ? 243 VAL A CG1 1 
ATOM   1966  C CG2 . VAL A 1 243 ? -4.253  -30.605 -30.067 1.00 40.20  ? 243 VAL A CG2 1 
ATOM   1967  N N   . SER A 1 244 ? -7.987  -27.930 -29.381 1.00 33.78  ? 244 SER A N   1 
ATOM   1968  C CA  . SER A 1 244 ? -8.968  -27.234 -28.584 1.00 39.40  ? 244 SER A CA  1 
ATOM   1969  C C   . SER A 1 244 ? -10.387 -27.771 -28.845 1.00 41.37  ? 244 SER A C   1 
ATOM   1970  O O   . SER A 1 244 ? -11.170 -27.958 -27.910 1.00 37.04  ? 244 SER A O   1 
ATOM   1971  C CB  . SER A 1 244 ? -8.830  -25.718 -28.742 1.00 42.37  ? 244 SER A CB  1 
ATOM   1972  O OG  . SER A 1 244 ? -8.817  -25.286 -30.097 1.00 44.20  ? 244 SER A OG  1 
ATOM   1973  N N   . ALA A 1 245 ? -10.750 -28.031 -30.108 1.00 39.61  ? 245 ALA A N   1 
ATOM   1974  C CA  . ALA A 1 245 ? -12.108 -28.504 -30.385 1.00 37.19  ? 245 ALA A CA  1 
ATOM   1975  C C   . ALA A 1 245 ? -12.262 -29.917 -29.826 1.00 30.63  ? 245 ALA A C   1 
ATOM   1976  O O   . ALA A 1 245 ? -13.271 -30.289 -29.255 1.00 35.48  ? 245 ALA A O   1 
ATOM   1977  C CB  . ALA A 1 245 ? -12.400 -28.434 -31.876 1.00 39.46  ? 245 ALA A CB  1 
ATOM   1978  N N   . HIS A 1 246 ? -11.207 -30.700 -29.924 1.00 33.70  ? 246 HIS A N   1 
ATOM   1979  C CA  . HIS A 1 246 ? -11.263 -32.086 -29.521 1.00 33.72  ? 246 HIS A CA  1 
ATOM   1980  C C   . HIS A 1 246 ? -11.298 -32.173 -27.988 1.00 35.42  ? 246 HIS A C   1 
ATOM   1981  O O   . HIS A 1 246 ? -12.027 -32.982 -27.416 1.00 39.96  ? 246 HIS A O   1 
ATOM   1982  C CB  . HIS A 1 246 ? -10.050 -32.759 -30.139 1.00 36.00  ? 246 HIS A CB  1 
ATOM   1983  C CG  . HIS A 1 246 ? -10.018 -34.219 -29.892 1.00 35.90  ? 246 HIS A CG  1 
ATOM   1984  N ND1 . HIS A 1 246 ? -8.864  -34.917 -30.148 1.00 35.59  ? 246 HIS A ND1 1 
ATOM   1985  C CD2 . HIS A 1 246 ? -10.891 -35.068 -29.356 1.00 33.03  ? 246 HIS A CD2 1 
ATOM   1986  C CE1 . HIS A 1 246 ? -9.072  -36.191 -29.820 1.00 43.10  ? 246 HIS A CE1 1 
ATOM   1987  N NE2 . HIS A 1 246 ? -10.285 -36.290 -29.311 1.00 38.25  ? 246 HIS A NE2 1 
ATOM   1988  N N   . THR A 1 247 ? -10.537 -31.314 -27.314 1.00 37.56  ? 247 THR A N   1 
ATOM   1989  C CA  . THR A 1 247 ? -10.504 -31.330 -25.858 1.00 38.58  ? 247 THR A CA  1 
ATOM   1990  C C   . THR A 1 247 ? -11.885 -30.958 -25.357 1.00 35.49  ? 247 THR A C   1 
ATOM   1991  O O   . THR A 1 247 ? -12.396 -31.604 -24.464 1.00 39.78  ? 247 THR A O   1 
ATOM   1992  C CB  . THR A 1 247 ? -9.452  -30.374 -25.298 1.00 39.54  ? 247 THR A CB  1 
ATOM   1993  O OG1 . THR A 1 247 ? -8.192  -30.746 -25.841 1.00 38.25  ? 247 THR A OG1 1 
ATOM   1994  C CG2 . THR A 1 247 ? -9.390  -30.387 -23.797 1.00 43.16  ? 247 THR A CG2 1 
ATOM   1995  N N   . ASN A 1 248 ? -12.517 -29.971 -26.002 1.00 41.81  ? 248 ASN A N   1 
ATOM   1996  C CA  . ASN A 1 248 ? -13.890 -29.575 -25.693 1.00 40.54  ? 248 ASN A CA  1 
ATOM   1997  C C   . ASN A 1 248 ? -14.867 -30.757 -25.847 1.00 42.54  ? 248 ASN A C   1 
ATOM   1998  O O   . ASN A 1 248 ? -15.668 -31.020 -24.957 1.00 40.19  ? 248 ASN A O   1 
ATOM   1999  C CB  . ASN A 1 248 ? -14.287 -28.373 -26.557 1.00 41.98  ? 248 ASN A CB  1 
ATOM   2000  C CG  . ASN A 1 248 ? -15.710 -27.912 -26.308 1.00 45.44  ? 248 ASN A CG  1 
ATOM   2001  O OD1 . ASN A 1 248 ? -16.542 -27.910 -27.217 1.00 41.81  ? 248 ASN A OD1 1 
ATOM   2002  N ND2 . ASN A 1 248 ? -16.008 -27.598 -25.058 1.00 46.87  ? 248 ASN A ND2 1 
ATOM   2003  N N   . LEU A 1 249 ? -14.846 -31.447 -26.992 1.00 41.15  ? 249 LEU A N   1 
ATOM   2004  C CA  . LEU A 1 249 ? -15.702 -32.610 -27.224 1.00 40.36  ? 249 LEU A CA  1 
ATOM   2005  C C   . LEU A 1 249 ? -15.434 -33.719 -26.203 1.00 37.19  ? 249 LEU A C   1 
ATOM   2006  O O   . LEU A 1 249 ? -16.358 -34.274 -25.633 1.00 39.91  ? 249 LEU A O   1 
ATOM   2007  C CB  . LEU A 1 249 ? -15.464 -33.117 -28.658 1.00 40.67  ? 249 LEU A CB  1 
ATOM   2008  C CG  . LEU A 1 249 ? -16.026 -32.240 -29.784 1.00 42.40  ? 249 LEU A CG  1 
ATOM   2009  C CD1 . LEU A 1 249 ? -15.701 -32.802 -31.168 1.00 45.43  ? 249 LEU A CD1 1 
ATOM   2010  C CD2 . LEU A 1 249 ? -17.528 -32.083 -29.653 1.00 45.20  ? 249 LEU A CD2 1 
ATOM   2011  N N   . LEU A 1 250 ? -14.166 -34.036 -25.955 1.00 33.26  ? 250 LEU A N   1 
ATOM   2012  C CA  . LEU A 1 250 ? -13.792 -35.090 -25.019 1.00 36.51  ? 250 LEU A CA  1 
ATOM   2013  C C   . LEU A 1 250 ? -14.379 -34.851 -23.625 1.00 43.12  ? 250 LEU A C   1 
ATOM   2014  O O   . LEU A 1 250 ? -14.969 -35.739 -22.994 1.00 37.08  ? 250 LEU A O   1 
ATOM   2015  C CB  . LEU A 1 250 ? -12.257 -35.090 -25.001 1.00 38.62  ? 250 LEU A CB  1 
ATOM   2016  C CG  . LEU A 1 250 ? -11.533 -36.018 -24.019 1.00 39.79  ? 250 LEU A CG  1 
ATOM   2017  C CD1 . LEU A 1 250 ? -12.009 -37.437 -24.142 1.00 43.21  ? 250 LEU A CD1 1 
ATOM   2018  C CD2 . LEU A 1 250 ? -10.027 -35.965 -24.275 1.00 38.35  ? 250 LEU A CD2 1 
ATOM   2019  N N   . VAL A 1 251 ? -14.165 -33.636 -23.103 1.00 38.34  ? 251 VAL A N   1 
ATOM   2020  C CA  . VAL A 1 251 ? -14.585 -33.352 -21.747 1.00 36.90  ? 251 VAL A CA  1 
ATOM   2021  C C   . VAL A 1 251 ? -16.107 -33.258 -21.717 1.00 33.33  ? 251 VAL A C   1 
ATOM   2022  O O   . VAL A 1 251 ? -16.760 -33.677 -20.781 1.00 30.53  ? 251 VAL A O   1 
ATOM   2023  C CB  . VAL A 1 251 ? -13.910 -32.065 -21.257 1.00 36.93  ? 251 VAL A CB  1 
ATOM   2024  C CG1 . VAL A 1 251 ? -14.524 -31.600 -19.955 1.00 37.44  ? 251 VAL A CG1 1 
ATOM   2025  C CG2 . VAL A 1 251 ? -12.404 -32.245 -21.134 1.00 41.01  ? 251 VAL A CG2 1 
ATOM   2026  N N   . ASN A 1 252 ? -16.676 -32.668 -22.759 1.00 37.30  ? 252 ASN A N   1 
ATOM   2027  C CA  . ASN A 1 252 ? -18.120 -32.634 -22.952 1.00 40.15  ? 252 ASN A CA  1 
ATOM   2028  C C   . ASN A 1 252 ? -18.757 -34.020 -22.920 1.00 38.75  ? 252 ASN A C   1 
ATOM   2029  O O   . ASN A 1 252 ? -19.850 -34.149 -22.369 1.00 41.46  ? 252 ASN A O   1 
ATOM   2030  C CB  . ASN A 1 252 ? -18.476 -31.998 -24.291 1.00 43.57  ? 252 ASN A CB  1 
ATOM   2031  C CG  . ASN A 1 252 ? -19.960 -31.964 -24.556 1.00 46.86  ? 252 ASN A CG  1 
ATOM   2032  O OD1 . ASN A 1 252 ? -20.491 -32.876 -25.177 1.00 43.24  ? 252 ASN A OD1 1 
ATOM   2033  N ND2 . ASN A 1 252 ? -20.622 -30.943 -24.039 1.00 49.06  ? 252 ASN A ND2 1 
ATOM   2034  N N   . SER A 1 253 ? -18.077 -35.022 -23.515 1.00 38.56  ? 253 SER A N   1 
ATOM   2035  C CA  . SER A 1 253 ? -18.616 -36.371 -23.644 1.00 39.92  ? 253 SER A CA  1 
ATOM   2036  C C   . SER A 1 253 ? -18.860 -37.065 -22.305 1.00 42.64  ? 253 SER A C   1 
ATOM   2037  O O   . SER A 1 253 ? -19.560 -38.070 -22.262 1.00 42.08  ? 253 SER A O   1 
ATOM   2038  C CB  . SER A 1 253 ? -17.751 -37.232 -24.549 1.00 39.34  ? 253 SER A CB  1 
ATOM   2039  O OG  . SER A 1 253 ? -16.604 -37.768 -23.898 1.00 41.73  ? 253 SER A OG  1 
ATOM   2040  N N   . ALA A 1 254 ? -18.268 -36.582 -21.207 1.00 48.42  ? 254 ALA A N   1 
ATOM   2041  C CA  . ALA A 1 254 ? -18.518 -37.189 -19.904 1.00 48.07  ? 254 ALA A CA  1 
ATOM   2042  C C   . ALA A 1 254 ? -19.578 -36.399 -19.157 1.00 38.79  ? 254 ALA A C   1 
ATOM   2043  O O   . ALA A 1 254 ? -19.728 -36.597 -17.964 1.00 40.21  ? 254 ALA A O   1 
ATOM   2044  C CB  . ALA A 1 254 ? -17.235 -37.304 -19.097 1.00 47.92  ? 254 ALA A CB  1 
ATOM   2045  N N   . TYR A 1 255 ? -20.298 -35.533 -19.877 1.00 44.39  ? 255 TYR A N   1 
ATOM   2046  C CA  . TYR A 1 255 ? -21.389 -34.705 -19.369 1.00 44.80  ? 255 TYR A CA  1 
ATOM   2047  C C   . TYR A 1 255 ? -20.883 -33.555 -18.492 1.00 47.29  ? 255 TYR A C   1 
ATOM   2048  O O   . TYR A 1 255 ? -21.639 -33.015 -17.707 1.00 50.96  ? 255 TYR A O   1 
ATOM   2049  C CB  . TYR A 1 255 ? -22.429 -35.530 -18.604 1.00 48.61  ? 255 TYR A CB  1 
ATOM   2050  C CG  . TYR A 1 255 ? -23.368 -36.377 -19.433 1.00 50.35  ? 255 TYR A CG  1 
ATOM   2051  C CD1 . TYR A 1 255 ? -23.308 -36.424 -20.824 1.00 50.50  ? 255 TYR A CD1 1 
ATOM   2052  C CD2 . TYR A 1 255 ? -24.342 -37.131 -18.801 1.00 49.60  ? 255 TYR A CD2 1 
ATOM   2053  C CE1 . TYR A 1 255 ? -24.156 -37.240 -21.556 1.00 51.93  ? 255 TYR A CE1 1 
ATOM   2054  C CE2 . TYR A 1 255 ? -25.183 -37.966 -19.512 1.00 55.22  ? 255 TYR A CE2 1 
ATOM   2055  C CZ  . TYR A 1 255 ? -25.097 -38.009 -20.893 1.00 56.56  ? 255 TYR A CZ  1 
ATOM   2056  O OH  . TYR A 1 255 ? -25.978 -38.811 -21.565 1.00 61.20  ? 255 TYR A OH  1 
ATOM   2057  N N   . SER A 1 256 ? -19.618 -33.162 -18.628 1.00 41.97  ? 256 SER A N   1 
ATOM   2058  C CA  . SER A 1 256 ? -19.117 -31.946 -18.018 1.00 43.76  ? 256 SER A CA  1 
ATOM   2059  C C   . SER A 1 256 ? -19.612 -30.748 -18.825 1.00 40.65  ? 256 SER A C   1 
ATOM   2060  O O   . SER A 1 256 ? -19.569 -30.757 -20.057 1.00 38.13  ? 256 SER A O   1 
ATOM   2061  C CB  . SER A 1 256 ? -17.593 -31.930 -17.963 1.00 44.95  ? 256 SER A CB  1 
ATOM   2062  O OG  . SER A 1 256 ? -17.091 -32.929 -17.099 1.00 50.57  ? 256 SER A OG  1 
ATOM   2063  N N   . ASP A 1 257 ? -19.969 -29.684 -18.110 1.00 39.03  ? 257 ASP A N   1 
ATOM   2064  C CA  . ASP A 1 257 ? -20.570 -28.501 -18.699 1.00 39.20  ? 257 ASP A CA  1 
ATOM   2065  C C   . ASP A 1 257 ? -19.569 -27.701 -19.532 1.00 35.37  ? 257 ASP A C   1 
ATOM   2066  O O   . ASP A 1 257 ? -18.368 -27.966 -19.552 1.00 37.89  ? 257 ASP A O   1 
ATOM   2067  C CB  . ASP A 1 257 ? -21.228 -27.664 -17.603 1.00 41.15  ? 257 ASP A CB  1 
ATOM   2068  C CG  . ASP A 1 257 ? -20.238 -27.131 -16.586 1.00 45.15  ? 257 ASP A CG  1 
ATOM   2069  O OD1 . ASP A 1 257 ? -19.373 -26.274 -16.994 1.00 42.01  ? 257 ASP A OD1 1 
ATOM   2070  O OD2 . ASP A 1 257 ? -20.346 -27.571 -15.398 1.00 43.75  ? 257 ASP A OD2 1 
ATOM   2071  N N   . ILE A 1 258 ? -20.087 -26.688 -20.232 1.00 36.34  ? 258 ILE A N   1 
ATOM   2072  C CA  . ILE A 1 258 ? -19.291 -25.947 -21.194 1.00 36.71  ? 258 ILE A CA  1 
ATOM   2073  C C   . ILE A 1 258 ? -18.219 -25.113 -20.484 1.00 36.44  ? 258 ILE A C   1 
ATOM   2074  O O   . ILE A 1 258 ? -17.215 -24.800 -21.095 1.00 31.51  ? 258 ILE A O   1 
ATOM   2075  C CB  . ILE A 1 258 ? -20.192 -25.078 -22.092 1.00 33.24  ? 258 ILE A CB  1 
ATOM   2076  C CG1 . ILE A 1 258 ? -19.479 -24.546 -23.336 1.00 39.72  ? 258 ILE A CG1 1 
ATOM   2077  C CG2 . ILE A 1 258 ? -20.759 -23.943 -21.295 1.00 33.11  ? 258 ILE A CG2 1 
ATOM   2078  C CD1 . ILE A 1 258 ? -19.210 -25.583 -24.402 1.00 40.82  ? 258 ILE A CD1 1 
ATOM   2079  N N   . TYR A 1 259 ? -18.422 -24.733 -19.220 1.00 33.67  ? 259 TYR A N   1 
ATOM   2080  C CA  . TYR A 1 259 ? -17.367 -24.026 -18.520 1.00 35.95  ? 259 TYR A CA  1 
ATOM   2081  C C   . TYR A 1 259 ? -16.192 -24.949 -18.269 1.00 35.11  ? 259 TYR A C   1 
ATOM   2082  O O   . TYR A 1 259 ? -15.027 -24.567 -18.444 1.00 40.89  ? 259 TYR A O   1 
ATOM   2083  C CB  . TYR A 1 259 ? -17.849 -23.436 -17.194 1.00 37.48  ? 259 TYR A CB  1 
ATOM   2084  C CG  . TYR A 1 259 ? -18.982 -22.470 -17.364 1.00 32.40  ? 259 TYR A CG  1 
ATOM   2085  C CD1 . TYR A 1 259 ? -18.726 -21.158 -17.702 1.00 33.76  ? 259 TYR A CD1 1 
ATOM   2086  C CD2 . TYR A 1 259 ? -20.291 -22.862 -17.185 1.00 33.52  ? 259 TYR A CD2 1 
ATOM   2087  C CE1 . TYR A 1 259 ? -19.753 -20.249 -17.852 1.00 34.23  ? 259 TYR A CE1 1 
ATOM   2088  C CE2 . TYR A 1 259 ? -21.335 -21.970 -17.351 1.00 31.97  ? 259 TYR A CE2 1 
ATOM   2089  C CZ  . TYR A 1 259 ? -21.061 -20.651 -17.644 1.00 33.66  ? 259 TYR A CZ  1 
ATOM   2090  O OH  . TYR A 1 259 ? -22.044 -19.722 -17.868 1.00 30.05  ? 259 TYR A OH  1 
ATOM   2091  N N   . ARG A 1 260 ? -16.491 -26.189 -17.894 1.00 39.10  ? 260 ARG A N   1 
ATOM   2092  C CA  . ARG A 1 260 ? -15.427 -27.173 -17.759 1.00 36.56  ? 260 ARG A CA  1 
ATOM   2093  C C   . ARG A 1 260 ? -14.798 -27.575 -19.093 1.00 33.67  ? 260 ARG A C   1 
ATOM   2094  O O   . ARG A 1 260 ? -13.583 -27.609 -19.198 1.00 35.87  ? 260 ARG A O   1 
ATOM   2095  C CB  . ARG A 1 260 ? -15.980 -28.357 -16.984 1.00 42.05  ? 260 ARG A CB  1 
ATOM   2096  C CG  . ARG A 1 260 ? -16.001 -28.119 -15.483 1.00 39.18  ? 260 ARG A CG  1 
ATOM   2097  C CD  . ARG A 1 260 ? -16.794 -29.205 -14.794 1.00 38.56  ? 260 ARG A CD  1 
ATOM   2098  N NE  . ARG A 1 260 ? -16.620 -29.123 -13.365 1.00 43.68  ? 260 ARG A NE  1 
ATOM   2099  C CZ  . ARG A 1 260 ? -17.405 -29.726 -12.492 1.00 43.31  ? 260 ARG A CZ  1 
ATOM   2100  N NH1 . ARG A 1 260 ? -18.458 -30.365 -12.940 1.00 38.84  ? 260 ARG A NH1 1 
ATOM   2101  N NH2 . ARG A 1 260 ? -17.145 -29.668 -11.192 1.00 39.53  ? 260 ARG A NH2 1 
ATOM   2102  N N   . SER A 1 261 ? -15.589 -27.891 -20.126 1.00 36.62  ? 261 SER A N   1 
ATOM   2103  C CA  . SER A 1 261 ? -15.015 -28.372 -21.389 1.00 31.60  ? 261 SER A CA  1 
ATOM   2104  C C   . SER A 1 261 ? -14.275 -27.243 -22.116 1.00 33.65  ? 261 SER A C   1 
ATOM   2105  O O   . SER A 1 261 ? -13.188 -27.431 -22.698 1.00 34.61  ? 261 SER A O   1 
ATOM   2106  C CB  . SER A 1 261 ? -16.072 -29.011 -22.269 1.00 31.91  ? 261 SER A CB  1 
ATOM   2107  O OG  . SER A 1 261 ? -17.109 -28.101 -22.655 1.00 29.68  ? 261 SER A OG  1 
ATOM   2108  N N   . PHE A 1 262 ? -14.785 -26.012 -22.008 1.00 34.75  ? 262 PHE A N   1 
ATOM   2109  C CA  . PHE A 1 262 ? -14.140 -24.950 -22.756 1.00 32.39  ? 262 PHE A CA  1 
ATOM   2110  C C   . PHE A 1 262 ? -12.877 -24.462 -22.043 1.00 34.47  ? 262 PHE A C   1 
ATOM   2111  O O   . PHE A 1 262 ? -11.900 -24.117 -22.690 1.00 33.94  ? 262 PHE A O   1 
ATOM   2112  C CB  . PHE A 1 262 ? -15.113 -23.837 -23.097 1.00 32.91  ? 262 PHE A CB  1 
ATOM   2113  C CG  . PHE A 1 262 ? -14.479 -22.812 -24.001 1.00 34.57  ? 262 PHE A CG  1 
ATOM   2114  C CD1 . PHE A 1 262 ? -14.135 -23.146 -25.297 1.00 33.08  ? 262 PHE A CD1 1 
ATOM   2115  C CD2 . PHE A 1 262 ? -14.116 -21.569 -23.515 1.00 34.95  ? 262 PHE A CD2 1 
ATOM   2116  C CE1 . PHE A 1 262 ? -13.549 -22.214 -26.139 1.00 34.78  ? 262 PHE A CE1 1 
ATOM   2117  C CE2 . PHE A 1 262 ? -13.491 -20.653 -24.345 1.00 39.46  ? 262 PHE A CE2 1 
ATOM   2118  C CZ  . PHE A 1 262 ? -13.227 -20.972 -25.662 1.00 36.68  ? 262 PHE A CZ  1 
ATOM   2119  N N   . SER A 1 263 ? -12.845 -24.492 -20.710 1.00 32.73  ? 263 SER A N   1 
ATOM   2120  C CA  . SER A 1 263 ? -11.637 -24.087 -20.018 1.00 33.19  ? 263 SER A CA  1 
ATOM   2121  C C   . SER A 1 263 ? -10.571 -25.144 -20.256 1.00 33.02  ? 263 SER A C   1 
ATOM   2122  O O   . SER A 1 263 ? -9.408  -24.809 -20.463 1.00 31.04  ? 263 SER A O   1 
ATOM   2123  C CB  . SER A 1 263 ? -11.879 -23.816 -18.556 1.00 33.24  ? 263 SER A CB  1 
ATOM   2124  O OG  . SER A 1 263 ? -12.344 -24.981 -17.903 1.00 35.33  ? 263 SER A OG  1 
ATOM   2125  N N   . ALA A 1 264 ? -10.984 -26.417 -20.303 1.00 33.65  ? 264 ALA A N   1 
ATOM   2126  C CA  . ALA A 1 264 ? -10.064 -27.482 -20.653 1.00 33.02  ? 264 ALA A CA  1 
ATOM   2127  C C   . ALA A 1 264 ? -9.509  -27.229 -22.065 1.00 34.19  ? 264 ALA A C   1 
ATOM   2128  O O   . ALA A 1 264 ? -8.290  -27.188 -22.261 1.00 33.94  ? 264 ALA A O   1 
ATOM   2129  C CB  . ALA A 1 264 ? -10.756 -28.824 -20.493 1.00 33.30  ? 264 ALA A CB  1 
ATOM   2130  N N   . ALA A 1 265 ? -10.391 -26.895 -23.014 1.00 33.33  ? 265 ALA A N   1 
ATOM   2131  C CA  . ALA A 1 265 ? -9.952  -26.605 -24.377 1.00 37.95  ? 265 ALA A CA  1 
ATOM   2132  C C   . ALA A 1 265 ? -8.936  -25.471 -24.415 1.00 40.35  ? 265 ALA A C   1 
ATOM   2133  O O   . ALA A 1 265 ? -8.028  -25.492 -25.254 1.00 37.06  ? 265 ALA A O   1 
ATOM   2134  C CB  . ALA A 1 265 ? -11.118 -26.242 -25.258 1.00 35.26  ? 265 ALA A CB  1 
ATOM   2135  N N   . MET A 1 266 ? -9.120  -24.465 -23.539 1.00 36.55  ? 266 MET A N   1 
ATOM   2136  C CA  . MET A 1 266 ? -8.270  -23.290 -23.580 1.00 33.36  ? 266 MET A CA  1 
ATOM   2137  C C   . MET A 1 266 ? -6.872  -23.644 -23.085 1.00 33.04  ? 266 MET A C   1 
ATOM   2138  O O   . MET A 1 266 ? -5.885  -23.099 -23.575 1.00 32.33  ? 266 MET A O   1 
ATOM   2139  C CB  . MET A 1 266 ? -8.851  -22.144 -22.739 1.00 36.71  ? 266 MET A CB  1 
ATOM   2140  C CG  . MET A 1 266 ? -10.031 -21.461 -23.402 1.00 36.55  ? 266 MET A CG  1 
ATOM   2141  S SD  . MET A 1 266 ? -9.620  -20.842 -25.046 1.00 38.72  ? 266 MET A SD  1 
ATOM   2142  C CE  . MET A 1 266 ? -10.174 -22.189 -26.094 1.00 37.37  ? 266 MET A CE  1 
ATOM   2143  N N   . ASN A 1 267 ? -6.799  -24.561 -22.118 1.00 32.53  ? 267 ASN A N   1 
ATOM   2144  C CA  . ASN A 1 267 ? -5.526  -25.089 -21.667 1.00 32.06  ? 267 ASN A CA  1 
ATOM   2145  C C   . ASN A 1 267 ? -4.779  -25.762 -22.823 1.00 35.61  ? 267 ASN A C   1 
ATOM   2146  O O   . ASN A 1 267 ? -3.558  -25.721 -22.872 1.00 37.76  ? 267 ASN A O   1 
ATOM   2147  C CB  . ASN A 1 267 ? -5.753  -26.080 -20.535 1.00 33.93  ? 267 ASN A CB  1 
ATOM   2148  C CG  . ASN A 1 267 ? -6.111  -25.390 -19.242 1.00 36.84  ? 267 ASN A CG  1 
ATOM   2149  O OD1 . ASN A 1 267 ? -6.113  -24.165 -19.156 1.00 37.71  ? 267 ASN A OD1 1 
ATOM   2150  N ND2 . ASN A 1 267 ? -6.348  -26.173 -18.213 1.00 37.34  ? 267 ASN A ND2 1 
ATOM   2151  N N   . GLY A 1 268 ? -5.518  -26.382 -23.752 1.00 36.15  ? 268 GLY A N   1 
ATOM   2152  C CA  . GLY A 1 268 ? -4.929  -26.999 -24.930 1.00 34.30  ? 268 GLY A CA  1 
ATOM   2153  C C   . GLY A 1 268 ? -4.521  -25.919 -25.927 1.00 36.94  ? 268 GLY A C   1 
ATOM   2154  O O   . GLY A 1 268 ? -3.443  -25.943 -26.494 1.00 38.17  ? 268 GLY A O   1 
ATOM   2155  N N   . LEU A 1 269 ? -5.405  -24.953 -26.131 1.00 37.49  ? 269 LEU A N   1 
ATOM   2156  C CA  . LEU A 1 269 ? -5.075  -23.866 -27.021 1.00 35.59  ? 269 LEU A CA  1 
ATOM   2157  C C   . LEU A 1 269 ? -3.826  -23.156 -26.524 1.00 38.82  ? 269 LEU A C   1 
ATOM   2158  O O   . LEU A 1 269 ? -3.120  -22.557 -27.329 1.00 41.05  ? 269 LEU A O   1 
ATOM   2159  C CB  . LEU A 1 269 ? -6.255  -22.915 -27.152 1.00 36.04  ? 269 LEU A CB  1 
ATOM   2160  C CG  . LEU A 1 269 ? -6.032  -21.825 -28.191 1.00 41.44  ? 269 LEU A CG  1 
ATOM   2161  C CD1 . LEU A 1 269 ? -5.883  -22.448 -29.585 1.00 46.06  ? 269 LEU A CD1 1 
ATOM   2162  C CD2 . LEU A 1 269 ? -7.132  -20.786 -28.165 1.00 39.60  ? 269 LEU A CD2 1 
ATOM   2163  N N   . ALA A 1 270 ? -3.538  -23.240 -25.214 1.00 40.47  ? 270 ALA A N   1 
ATOM   2164  C CA  . ALA A 1 270 ? -2.419  -22.502 -24.645 1.00 41.05  ? 270 ALA A CA  1 
ATOM   2165  C C   . ALA A 1 270 ? -1.096  -23.113 -25.087 1.00 39.26  ? 270 ALA A C   1 
ATOM   2166  O O   . ALA A 1 270 ? -0.057  -22.488 -24.919 1.00 38.23  ? 270 ALA A O   1 
ATOM   2167  C CB  . ALA A 1 270 ? -2.485  -22.499 -23.146 1.00 42.94  ? 270 ALA A CB  1 
ATOM   2168  N N   . GLY A 1 271 ? -1.160  -24.343 -25.602 1.00 36.11  ? 271 GLY A N   1 
ATOM   2169  C CA  . GLY A 1 271 ? 0.026   -25.079 -25.980 1.00 35.56  ? 271 GLY A CA  1 
ATOM   2170  C C   . GLY A 1 271 ? 0.744   -24.382 -27.133 1.00 38.05  ? 271 GLY A C   1 
ATOM   2171  O O   . GLY A 1 271 ? 0.101   -23.928 -28.091 1.00 34.68  ? 271 GLY A O   1 
ATOM   2172  N N   . PRO A 1 272 ? 2.088   -24.301 -27.077 1.00 37.14  ? 272 PRO A N   1 
ATOM   2173  C CA  . PRO A 1 272 ? 2.881   -23.736 -28.177 1.00 40.22  ? 272 PRO A CA  1 
ATOM   2174  C C   . PRO A 1 272 ? 2.600   -24.273 -29.585 1.00 49.36  ? 272 PRO A C   1 
ATOM   2175  O O   . PRO A 1 272 ? 2.665   -23.522 -30.552 1.00 52.23  ? 272 PRO A O   1 
ATOM   2176  C CB  . PRO A 1 272 ? 4.302   -24.098 -27.744 1.00 41.95  ? 272 PRO A CB  1 
ATOM   2177  C CG  . PRO A 1 272 ? 4.241   -24.065 -26.205 1.00 43.92  ? 272 PRO A CG  1 
ATOM   2178  C CD  . PRO A 1 272 ? 2.905   -24.695 -25.916 1.00 42.51  ? 272 PRO A CD  1 
ATOM   2179  N N   . LEU A 1 273 ? 2.245   -25.562 -29.702 1.00 47.21  ? 273 LEU A N   1 
ATOM   2180  C CA  . LEU A 1 273 ? 2.002   -26.170 -30.995 1.00 46.55  ? 273 LEU A CA  1 
ATOM   2181  C C   . LEU A 1 273 ? 0.595   -25.849 -31.514 1.00 48.09  ? 273 LEU A C   1 
ATOM   2182  O O   . LEU A 1 273 ? 0.305   -26.112 -32.669 1.00 48.45  ? 273 LEU A O   1 
ATOM   2183  C CB  . LEU A 1 273 ? 2.197   -27.683 -30.850 1.00 46.25  ? 273 LEU A CB  1 
ATOM   2184  C CG  . LEU A 1 273 ? 3.616   -28.161 -30.532 1.00 48.47  ? 273 LEU A CG  1 
ATOM   2185  C CD1 . LEU A 1 273 ? 3.702   -29.692 -30.580 1.00 45.95  ? 273 LEU A CD1 1 
ATOM   2186  C CD2 . LEU A 1 273 ? 4.641   -27.560 -31.489 1.00 46.23  ? 273 LEU A CD2 1 
ATOM   2187  N N   . HIS A 1 274 ? -0.292  -25.289 -30.681 1.00 49.18  ? 274 HIS A N   1 
ATOM   2188  C CA  . HIS A 1 274 ? -1.645  -24.983 -31.123 1.00 41.86  ? 274 HIS A CA  1 
ATOM   2189  C C   . HIS A 1 274 ? -1.897  -23.466 -31.213 1.00 41.62  ? 274 HIS A C   1 
ATOM   2190  O O   . HIS A 1 274 ? -2.475  -22.971 -32.180 1.00 47.24  ? 274 HIS A O   1 
ATOM   2191  C CB  . HIS A 1 274 ? -2.621  -25.799 -30.268 1.00 43.98  ? 274 HIS A CB  1 
ATOM   2192  C CG  . HIS A 1 274 ? -4.033  -25.721 -30.729 1.00 41.22  ? 274 HIS A CG  1 
ATOM   2193  N ND1 . HIS A 1 274 ? -4.380  -25.451 -32.034 1.00 42.77  ? 274 HIS A ND1 1 
ATOM   2194  C CD2 . HIS A 1 274 ? -5.189  -25.856 -30.058 1.00 44.34  ? 274 HIS A CD2 1 
ATOM   2195  C CE1 . HIS A 1 274 ? -5.710  -25.410 -32.145 1.00 42.15  ? 274 HIS A CE1 1 
ATOM   2196  N NE2 . HIS A 1 274 ? -6.227  -25.652 -30.953 1.00 42.02  ? 274 HIS A NE2 1 
ATOM   2197  N N   . GLY A 1 275 ? -1.461  -22.666 -30.241 1.00 49.20  ? 275 GLY A N   1 
ATOM   2198  C CA  . GLY A 1 275 ? -2.012  -21.319 -30.144 1.00 47.01  ? 275 GLY A CA  1 
ATOM   2199  C C   . GLY A 1 275 ? -1.024  -20.182 -30.397 1.00 48.47  ? 275 GLY A C   1 
ATOM   2200  O O   . GLY A 1 275 ? -1.379  -19.018 -30.229 1.00 53.23  ? 275 GLY A O   1 
ATOM   2201  N N   . LEU A 1 276 ? 0.195   -20.510 -30.808 1.00 45.99  ? 276 LEU A N   1 
ATOM   2202  C CA  . LEU A 1 276 ? 1.306   -19.580 -30.741 1.00 50.75  ? 276 LEU A CA  1 
ATOM   2203  C C   . LEU A 1 276 ? 1.733   -19.104 -32.136 1.00 49.19  ? 276 LEU A C   1 
ATOM   2204  O O   . LEU A 1 276 ? 2.544   -18.195 -32.235 1.00 50.05  ? 276 LEU A O   1 
ATOM   2205  C CB  . LEU A 1 276 ? 2.449   -20.316 -30.032 1.00 52.27  ? 276 LEU A CB  1 
ATOM   2206  C CG  . LEU A 1 276 ? 3.031   -19.653 -28.783 1.00 69.85  ? 276 LEU A CG  1 
ATOM   2207  C CD1 . LEU A 1 276 ? 4.195   -20.473 -28.236 1.00 70.08  ? 276 LEU A CD1 1 
ATOM   2208  C CD2 . LEU A 1 276 ? 3.499   -18.234 -29.067 1.00 80.22  ? 276 LEU A CD2 1 
ATOM   2209  N N   . ALA A 1 277 ? 1.201   -19.707 -33.206 1.00 45.53  ? 277 ALA A N   1 
ATOM   2210  C CA  . ALA A 1 277 ? 1.691   -19.492 -34.571 1.00 53.39  ? 277 ALA A CA  1 
ATOM   2211  C C   . ALA A 1 277 ? 1.630   -18.029 -35.044 1.00 54.57  ? 277 ALA A C   1 
ATOM   2212  O O   . ALA A 1 277 ? 2.584   -17.528 -35.645 1.00 55.37  ? 277 ALA A O   1 
ATOM   2213  C CB  . ALA A 1 277 ? 0.898   -20.373 -35.503 1.00 51.99  ? 277 ALA A CB  1 
ATOM   2214  N N   . ASN A 1 278 ? 0.500   -17.372 -34.803 1.00 60.88  ? 278 ASN A N   1 
ATOM   2215  C CA  . ASN A 1 278 ? 0.288   -15.953 -35.184 1.00 54.63  ? 278 ASN A CA  1 
ATOM   2216  C C   . ASN A 1 278 ? 1.461   -15.112 -34.690 1.00 50.22  ? 278 ASN A C   1 
ATOM   2217  O O   . ASN A 1 278 ? 1.936   -14.273 -35.461 1.00 51.82  ? 278 ASN A O   1 
ATOM   2218  C CB  . ASN A 1 278 ? -1.075  -15.545 -34.612 1.00 54.23  ? 278 ASN A CB  1 
ATOM   2219  C CG  . ASN A 1 278 ? -1.342  -14.069 -34.410 1.00 66.43  ? 278 ASN A CG  1 
ATOM   2220  O OD1 . ASN A 1 278 ? -0.634  -13.212 -34.923 1.00 88.83  ? 278 ASN A OD1 1 
ATOM   2221  N ND2 . ASN A 1 278 ? -2.408  -13.762 -33.691 1.00 66.11  ? 278 ASN A ND2 1 
ATOM   2222  N N   . GLN A 1 279 ? 1.925   -15.357 -33.470 1.00 48.17  ? 279 GLN A N   1 
ATOM   2223  C CA  . GLN A 1 279 ? 2.959   -14.520 -32.861 1.00 52.33  ? 279 GLN A CA  1 
ATOM   2224  C C   . GLN A 1 279 ? 4.346   -14.804 -33.453 1.00 51.24  ? 279 GLN A C   1 
ATOM   2225  O O   . GLN A 1 279 ? 5.146   -13.881 -33.637 1.00 43.97  ? 279 GLN A O   1 
ATOM   2226  C CB  . GLN A 1 279 ? 3.061   -14.778 -31.351 1.00 54.67  ? 279 GLN A CB  1 
ATOM   2227  C CG  . GLN A 1 279 ? 1.713   -14.980 -30.665 1.00 63.96  ? 279 GLN A CG  1 
ATOM   2228  C CD  . GLN A 1 279 ? 1.787   -15.368 -29.204 1.00 66.11  ? 279 GLN A CD  1 
ATOM   2229  O OE1 . GLN A 1 279 ? 2.852   -15.359 -28.562 1.00 65.01  ? 279 GLN A OE1 1 
ATOM   2230  N NE2 . GLN A 1 279 ? 0.623   -15.724 -28.674 1.00 53.21  ? 279 GLN A NE2 1 
ATOM   2231  N N   . GLU A 1 280 ? 4.666   -16.090 -33.641 1.00 43.97  ? 280 GLU A N   1 
ATOM   2232  C CA  . GLU A 1 280 ? 5.907   -16.472 -34.291 1.00 62.63  ? 280 GLU A CA  1 
ATOM   2233  C C   . GLU A 1 280 ? 6.015   -15.756 -35.635 1.00 54.88  ? 280 GLU A C   1 
ATOM   2234  O O   . GLU A 1 280 ? 7.067   -15.213 -35.956 1.00 48.96  ? 280 GLU A O   1 
ATOM   2235  C CB  . GLU A 1 280 ? 5.988   -17.979 -34.572 1.00 72.16  ? 280 GLU A CB  1 
ATOM   2236  C CG  . GLU A 1 280 ? 6.053   -18.870 -33.340 1.00 84.80  ? 280 GLU A CG  1 
ATOM   2237  C CD  . GLU A 1 280 ? 5.878   -20.352 -33.667 1.00 102.34 ? 280 GLU A CD  1 
ATOM   2238  O OE1 . GLU A 1 280 ? 5.623   -21.154 -32.718 1.00 87.23  ? 280 GLU A OE1 1 
ATOM   2239  O OE2 . GLU A 1 280 ? 6.001   -20.715 -34.879 1.00 99.82  ? 280 GLU A OE2 1 
ATOM   2240  N N   . VAL A 1 281 ? 4.936   -15.795 -36.430 1.00 48.20  ? 281 VAL A N   1 
ATOM   2241  C CA  . VAL A 1 281 ? 4.970   -15.158 -37.734 1.00 49.06  ? 281 VAL A CA  1 
ATOM   2242  C C   . VAL A 1 281 ? 5.303   -13.667 -37.551 1.00 53.76  ? 281 VAL A C   1 
ATOM   2243  O O   . VAL A 1 281 ? 6.265   -13.156 -38.148 1.00 51.47  ? 281 VAL A O   1 
ATOM   2244  C CB  . VAL A 1 281 ? 3.679   -15.432 -38.542 1.00 46.77  ? 281 VAL A CB  1 
ATOM   2245  C CG1 . VAL A 1 281 ? 3.547   -14.567 -39.803 1.00 45.42  ? 281 VAL A CG1 1 
ATOM   2246  C CG2 . VAL A 1 281 ? 3.562   -16.895 -38.928 1.00 43.89  ? 281 VAL A CG2 1 
ATOM   2247  N N   . LEU A 1 282 ? 4.548   -12.960 -36.695 1.00 49.97  ? 282 LEU A N   1 
ATOM   2248  C CA  . LEU A 1 282 ? 4.763   -11.527 -36.528 1.00 49.26  ? 282 LEU A CA  1 
ATOM   2249  C C   . LEU A 1 282 ? 6.212   -11.240 -36.123 1.00 48.58  ? 282 LEU A C   1 
ATOM   2250  O O   . LEU A 1 282 ? 6.846   -10.335 -36.663 1.00 45.88  ? 282 LEU A O   1 
ATOM   2251  C CB  . LEU A 1 282 ? 3.765   -10.947 -35.518 1.00 47.81  ? 282 LEU A CB  1 
ATOM   2252  C CG  . LEU A 1 282 ? 3.835   -9.428  -35.337 1.00 48.92  ? 282 LEU A CG  1 
ATOM   2253  C CD1 . LEU A 1 282 ? 3.588   -8.702  -36.657 1.00 51.33  ? 282 LEU A CD1 1 
ATOM   2254  C CD2 . LEU A 1 282 ? 2.841   -8.952  -34.289 1.00 50.85  ? 282 LEU A CD2 1 
ATOM   2255  N N   . ARG A 1 283 ? 6.762   -12.036 -35.202 1.00 50.62  ? 283 ARG A N   1 
ATOM   2256  C CA  . ARG A 1 283 ? 8.135   -11.828 -34.760 1.00 50.17  ? 283 ARG A CA  1 
ATOM   2257  C C   . ARG A 1 283 ? 9.094   -11.988 -35.946 1.00 44.19  ? 283 ARG A C   1 
ATOM   2258  O O   . ARG A 1 283 ? 10.058  -11.247 -36.092 1.00 42.36  ? 283 ARG A O   1 
ATOM   2259  C CB  . ARG A 1 283 ? 8.478   -12.777 -33.607 1.00 47.89  ? 283 ARG A CB  1 
ATOM   2260  C CG  . ARG A 1 283 ? 7.855   -12.361 -32.283 1.00 53.69  ? 283 ARG A CG  1 
ATOM   2261  C CD  . ARG A 1 283 ? 8.283   -13.278 -31.160 1.00 55.12  ? 283 ARG A CD  1 
ATOM   2262  N NE  . ARG A 1 283 ? 7.624   -13.026 -29.888 1.00 58.01  ? 283 ARG A NE  1 
ATOM   2263  C CZ  . ARG A 1 283 ? 7.877   -11.992 -29.088 1.00 60.14  ? 283 ARG A CZ  1 
ATOM   2264  N NH1 . ARG A 1 283 ? 8.691   -11.031 -29.491 1.00 53.73  ? 283 ARG A NH1 1 
ATOM   2265  N NH2 . ARG A 1 283 ? 7.295   -11.908 -27.898 1.00 54.15  ? 283 ARG A NH2 1 
ATOM   2266  N N   . TRP A 1 284 ? 8.804   -12.979 -36.772 1.00 41.36  ? 284 TRP A N   1 
ATOM   2267  C CA  . TRP A 1 284 ? 9.636   -13.346 -37.895 1.00 50.91  ? 284 TRP A CA  1 
ATOM   2268  C C   . TRP A 1 284 ? 9.598   -12.228 -38.939 1.00 52.21  ? 284 TRP A C   1 
ATOM   2269  O O   . TRP A 1 284 ? 10.644  -11.760 -39.389 1.00 49.51  ? 284 TRP A O   1 
ATOM   2270  C CB  . TRP A 1 284 ? 9.152   -14.703 -38.425 1.00 49.68  ? 284 TRP A CB  1 
ATOM   2271  C CG  . TRP A 1 284 ? 9.953   -15.297 -39.536 1.00 54.47  ? 284 TRP A CG  1 
ATOM   2272  C CD1 . TRP A 1 284 ? 11.086  -16.051 -39.417 1.00 53.22  ? 284 TRP A CD1 1 
ATOM   2273  C CD2 . TRP A 1 284 ? 9.654   -15.214 -40.945 1.00 57.03  ? 284 TRP A CD2 1 
ATOM   2274  N NE1 . TRP A 1 284 ? 11.525  -16.413 -40.661 1.00 57.61  ? 284 TRP A NE1 1 
ATOM   2275  C CE2 . TRP A 1 284 ? 10.672  -15.920 -41.617 1.00 56.07  ? 284 TRP A CE2 1 
ATOM   2276  C CE3 . TRP A 1 284 ? 8.645   -14.608 -41.706 1.00 60.09  ? 284 TRP A CE3 1 
ATOM   2277  C CZ2 . TRP A 1 284 ? 10.688  -16.053 -43.007 1.00 53.41  ? 284 TRP A CZ2 1 
ATOM   2278  C CZ3 . TRP A 1 284 ? 8.666   -14.727 -43.081 1.00 53.49  ? 284 TRP A CZ3 1 
ATOM   2279  C CH2 . TRP A 1 284 ? 9.679   -15.445 -43.720 1.00 53.18  ? 284 TRP A CH2 1 
ATOM   2280  N N   . ILE A 1 285 ? 8.376   -11.775 -39.260 1.00 53.14  ? 285 ILE A N   1 
ATOM   2281  C CA  . ILE A 1 285 ? 8.161   -10.652 -40.155 1.00 52.61  ? 285 ILE A CA  1 
ATOM   2282  C C   . ILE A 1 285 ? 8.895   -9.411  -39.643 1.00 54.81  ? 285 ILE A C   1 
ATOM   2283  O O   . ILE A 1 285 ? 9.497   -8.688  -40.446 1.00 52.80  ? 285 ILE A O   1 
ATOM   2284  C CB  . ILE A 1 285 ? 6.658   -10.383 -40.342 1.00 51.14  ? 285 ILE A CB  1 
ATOM   2285  C CG1 . ILE A 1 285 ? 5.933   -11.538 -41.052 1.00 49.89  ? 285 ILE A CG1 1 
ATOM   2286  C CG2 . ILE A 1 285 ? 6.457   -9.048  -41.041 1.00 52.62  ? 285 ILE A CG2 1 
ATOM   2287  C CD1 . ILE A 1 285 ? 6.229   -11.676 -42.537 1.00 50.91  ? 285 ILE A CD1 1 
ATOM   2288  N N   . GLN A 1 286 ? 8.863   -9.175  -38.319 1.00 52.02  ? 286 GLN A N   1 
ATOM   2289  C CA  . GLN A 1 286 ? 9.515   -8.000  -37.756 1.00 52.82  ? 286 GLN A CA  1 
ATOM   2290  C C   . GLN A 1 286 ? 11.033  -8.185  -37.772 1.00 51.05  ? 286 GLN A C   1 
ATOM   2291  O O   . GLN A 1 286 ? 11.766  -7.184  -37.738 1.00 51.32  ? 286 GLN A O   1 
ATOM   2292  C CB  . GLN A 1 286 ? 9.062   -7.704  -36.319 1.00 47.41  ? 286 GLN A CB  1 
ATOM   2293  C CG  . GLN A 1 286 ? 7.630   -7.205  -36.191 1.00 51.39  ? 286 GLN A CG  1 
ATOM   2294  C CD  . GLN A 1 286 ? 7.127   -7.385  -34.775 1.00 53.24  ? 286 GLN A CD  1 
ATOM   2295  O OE1 . GLN A 1 286 ? 7.221   -8.475  -34.206 1.00 46.92  ? 286 GLN A OE1 1 
ATOM   2296  N NE2 . GLN A 1 286 ? 6.611   -6.315  -34.182 1.00 43.72  ? 286 GLN A NE2 1 
ATOM   2297  N N   . MET A 1 287 ? 11.480  -9.452  -37.705 1.00 49.73  ? 287 MET A N   1 
ATOM   2298  C CA  . MET A 1 287 ? 12.899  -9.796  -37.746 1.00 59.92  ? 287 MET A CA  1 
ATOM   2299  C C   . MET A 1 287 ? 13.466  -9.517  -39.153 1.00 55.67  ? 287 MET A C   1 
ATOM   2300  O O   . MET A 1 287 ? 14.550  -8.945  -39.263 1.00 56.84  ? 287 MET A O   1 
ATOM   2301  C CB  . MET A 1 287 ? 13.123  -11.255 -37.287 1.00 69.28  ? 287 MET A CB  1 
ATOM   2302  C CG  . MET A 1 287 ? 14.531  -11.855 -37.543 1.00 60.20  ? 287 MET A CG  1 
ATOM   2303  S SD  . MET A 1 287 ? 14.746  -12.331 -39.297 1.00 59.64  ? 287 MET A SD  1 
ATOM   2304  C CE  . MET A 1 287 ? 13.673  -13.760 -39.445 1.00 61.85  ? 287 MET A CE  1 
ATOM   2305  N N   . LEU A 1 288 ? 12.710  -9.852  -40.216 1.00 50.82  ? 288 LEU A N   1 
ATOM   2306  C CA  . LEU A 1 288 ? 13.070  -9.502  -41.581 1.00 55.71  ? 288 LEU A CA  1 
ATOM   2307  C C   . LEU A 1 288 ? 13.207  -7.988  -41.727 1.00 64.85  ? 288 LEU A C   1 
ATOM   2308  O O   . LEU A 1 288 ? 14.243  -7.489  -42.166 1.00 66.02  ? 288 LEU A O   1 
ATOM   2309  C CB  . LEU A 1 288 ? 12.005  -10.044 -42.542 1.00 62.70  ? 288 LEU A CB  1 
ATOM   2310  C CG  . LEU A 1 288 ? 12.037  -11.559 -42.758 1.00 62.02  ? 288 LEU A CG  1 
ATOM   2311  C CD1 . LEU A 1 288 ? 10.821  -12.049 -43.532 1.00 64.85  ? 288 LEU A CD1 1 
ATOM   2312  C CD2 . LEU A 1 288 ? 13.310  -11.960 -43.480 1.00 65.95  ? 288 LEU A CD2 1 
ATOM   2313  N N   . TYR A 1 289 ? 12.147  -7.264  -41.359 1.00 64.94  ? 289 TYR A N   1 
ATOM   2314  C CA  . TYR A 1 289 ? 12.143  -5.807  -41.362 1.00 64.09  ? 289 TYR A CA  1 
ATOM   2315  C C   . TYR A 1 289 ? 13.446  -5.255  -40.784 1.00 60.97  ? 289 TYR A C   1 
ATOM   2316  O O   . TYR A 1 289 ? 14.140  -4.490  -41.436 1.00 59.60  ? 289 TYR A O   1 
ATOM   2317  C CB  . TYR A 1 289 ? 10.942  -5.253  -40.583 1.00 65.36  ? 289 TYR A CB  1 
ATOM   2318  C CG  . TYR A 1 289 ? 10.725  -3.775  -40.762 1.00 63.36  ? 289 TYR A CG  1 
ATOM   2319  C CD1 . TYR A 1 289 ? 10.131  -3.294  -41.907 1.00 65.45  ? 289 TYR A CD1 1 
ATOM   2320  C CD2 . TYR A 1 289 ? 11.164  -2.860  -39.821 1.00 67.11  ? 289 TYR A CD2 1 
ATOM   2321  C CE1 . TYR A 1 289 ? 9.940   -1.937  -42.104 1.00 84.00  ? 289 TYR A CE1 1 
ATOM   2322  C CE2 . TYR A 1 289 ? 10.989  -1.499  -40.002 1.00 83.56  ? 289 TYR A CE2 1 
ATOM   2323  C CZ  . TYR A 1 289 ? 10.376  -1.032  -41.154 1.00 93.10  ? 289 TYR A CZ  1 
ATOM   2324  O OH  . TYR A 1 289 ? 10.165  0.307   -41.390 1.00 89.65  ? 289 TYR A OH  1 
ATOM   2325  N N   . LYS A 1 290 ? 13.772  -5.636  -39.549 1.00 65.19  ? 290 LYS A N   1 
ATOM   2326  C CA  . LYS A 1 290 ? 14.935  -5.101  -38.850 1.00 64.58  ? 290 LYS A CA  1 
ATOM   2327  C C   . LYS A 1 290 ? 16.209  -5.495  -39.597 1.00 65.59  ? 290 LYS A C   1 
ATOM   2328  O O   . LYS A 1 290 ? 17.146  -4.715  -39.667 1.00 58.34  ? 290 LYS A O   1 
ATOM   2329  C CB  . LYS A 1 290 ? 14.971  -5.624  -37.407 1.00 63.76  ? 290 LYS A CB  1 
ATOM   2330  C CG  . LYS A 1 290 ? 16.132  -5.135  -36.560 1.00 68.62  ? 290 LYS A CG  1 
ATOM   2331  C CD  . LYS A 1 290 ? 16.221  -5.789  -35.187 1.00 75.17  ? 290 LYS A CD  1 
ATOM   2332  C CE  . LYS A 1 290 ? 17.184  -5.063  -34.268 1.00 74.40  ? 290 LYS A CE  1 
ATOM   2333  N NZ  . LYS A 1 290 ? 17.385  -5.804  -33.006 1.00 79.22  ? 290 LYS A NZ  1 
ATOM   2334  N N   . LYS A 1 291 ? 16.240  -6.718  -40.142 1.00 72.40  ? 291 LYS A N   1 
ATOM   2335  C CA  . LYS A 1 291 ? 17.437  -7.250  -40.771 1.00 71.09  ? 291 LYS A CA  1 
ATOM   2336  C C   . LYS A 1 291 ? 17.743  -6.487  -42.075 1.00 68.48  ? 291 LYS A C   1 
ATOM   2337  O O   . LYS A 1 291 ? 18.906  -6.185  -42.338 1.00 59.02  ? 291 LYS A O   1 
ATOM   2338  C CB  . LYS A 1 291 ? 17.280  -8.765  -40.939 1.00 72.85  ? 291 LYS A CB  1 
ATOM   2339  C CG  . LYS A 1 291 ? 18.414  -9.458  -41.690 1.00 86.05  ? 291 LYS A CG  1 
ATOM   2340  C CD  . LYS A 1 291 ? 18.297  -10.976 -41.742 1.00 86.96  ? 291 LYS A CD  1 
ATOM   2341  C CE  . LYS A 1 291 ? 19.110  -11.608 -42.854 1.00 84.72  ? 291 LYS A CE  1 
ATOM   2342  N NZ  . LYS A 1 291 ? 20.562  -11.386 -42.671 1.00 78.97  ? 291 LYS A NZ  1 
ATOM   2343  N N   . PHE A 1 292 ? 16.715  -6.138  -42.872 1.00 68.72  ? 292 PHE A N   1 
ATOM   2344  C CA  . PHE A 1 292 ? 16.906  -5.549  -44.197 1.00 69.19  ? 292 PHE A CA  1 
ATOM   2345  C C   . PHE A 1 292 ? 16.779  -4.025  -44.197 1.00 67.53  ? 292 PHE A C   1 
ATOM   2346  O O   . PHE A 1 292 ? 16.834  -3.409  -45.257 1.00 68.64  ? 292 PHE A O   1 
ATOM   2347  C CB  . PHE A 1 292 ? 15.946  -6.196  -45.194 1.00 64.90  ? 292 PHE A CB  1 
ATOM   2348  C CG  . PHE A 1 292 ? 16.352  -7.615  -45.499 1.00 78.38  ? 292 PHE A CG  1 
ATOM   2349  C CD1 . PHE A 1 292 ? 17.530  -7.876  -46.198 1.00 81.75  ? 292 PHE A CD1 1 
ATOM   2350  C CD2 . PHE A 1 292 ? 15.613  -8.689  -45.024 1.00 69.45  ? 292 PHE A CD2 1 
ATOM   2351  C CE1 . PHE A 1 292 ? 17.932  -9.179  -46.461 1.00 75.08  ? 292 PHE A CE1 1 
ATOM   2352  C CE2 . PHE A 1 292 ? 16.022  -9.991  -45.279 1.00 73.30  ? 292 PHE A CE2 1 
ATOM   2353  C CZ  . PHE A 1 292 ? 17.170  -10.233 -46.010 1.00 75.34  ? 292 PHE A CZ  1 
ATOM   2354  N N   . GLY A 1 293 ? 16.644  -3.417  -43.010 1.00 60.88  ? 293 GLY A N   1 
ATOM   2355  C CA  . GLY A 1 293 ? 16.426  -1.986  -42.902 1.00 59.85  ? 293 GLY A CA  1 
ATOM   2356  C C   . GLY A 1 293 ? 15.180  -1.537  -43.656 1.00 60.04  ? 293 GLY A C   1 
ATOM   2357  O O   . GLY A 1 293 ? 15.107  -0.408  -44.124 1.00 78.86  ? 293 GLY A O   1 
ATOM   2358  N N   . GLY A 1 294 ? 14.189  -2.418  -43.744 1.00 58.85  ? 294 GLY A N   1 
ATOM   2359  C CA  . GLY A 1 294 ? 12.946  -2.110  -44.424 1.00 60.31  ? 294 GLY A CA  1 
ATOM   2360  C C   . GLY A 1 294 ? 12.394  -3.347  -45.122 1.00 58.02  ? 294 GLY A C   1 
ATOM   2361  O O   . GLY A 1 294 ? 12.647  -4.473  -44.703 1.00 58.44  ? 294 GLY A O   1 
ATOM   2362  N N   . VAL A 1 295 ? 11.620  -3.117  -46.179 1.00 63.77  ? 295 VAL A N   1 
ATOM   2363  C CA  . VAL A 1 295 ? 11.031  -4.198  -46.952 1.00 62.95  ? 295 VAL A CA  1 
ATOM   2364  C C   . VAL A 1 295 ? 12.125  -4.755  -47.858 1.00 71.20  ? 295 VAL A C   1 
ATOM   2365  O O   . VAL A 1 295 ? 12.732  -4.006  -48.628 1.00 72.41  ? 295 VAL A O   1 
ATOM   2366  C CB  . VAL A 1 295 ? 9.822   -3.700  -47.769 1.00 54.63  ? 295 VAL A CB  1 
ATOM   2367  C CG1 . VAL A 1 295 ? 9.258   -4.793  -48.652 1.00 58.29  ? 295 VAL A CG1 1 
ATOM   2368  C CG2 . VAL A 1 295 ? 8.737   -3.098  -46.890 1.00 52.54  ? 295 VAL A CG2 1 
ATOM   2369  N N   . PRO A 1 296 ? 12.449  -6.065  -47.762 1.00 71.78  ? 296 PRO A N   1 
ATOM   2370  C CA  . PRO A 1 296 ? 13.422  -6.667  -48.665 1.00 70.56  ? 296 PRO A CA  1 
ATOM   2371  C C   . PRO A 1 296 ? 12.926  -6.692  -50.114 1.00 77.57  ? 296 PRO A C   1 
ATOM   2372  O O   . PRO A 1 296 ? 11.773  -6.338  -50.385 1.00 72.69  ? 296 PRO A O   1 
ATOM   2373  C CB  . PRO A 1 296 ? 13.635  -8.074  -48.091 1.00 73.11  ? 296 PRO A CB  1 
ATOM   2374  C CG  . PRO A 1 296 ? 12.424  -8.351  -47.234 1.00 72.27  ? 296 PRO A CG  1 
ATOM   2375  C CD  . PRO A 1 296 ? 11.940  -7.006  -46.754 1.00 70.76  ? 296 PRO A CD  1 
ATOM   2376  N N   . THR A 1 297 ? 13.843  -7.053  -51.029 1.00 68.12  ? 297 THR A N   1 
ATOM   2377  C CA  . THR A 1 297 ? 13.522  -7.321  -52.424 1.00 72.96  ? 297 THR A CA  1 
ATOM   2378  C C   . THR A 1 297 ? 13.166  -8.798  -52.582 1.00 76.58  ? 297 THR A C   1 
ATOM   2379  O O   . THR A 1 297 ? 13.394  -9.595  -51.657 1.00 64.90  ? 297 THR A O   1 
ATOM   2380  C CB  . THR A 1 297 ? 14.692  -6.940  -53.344 1.00 77.01  ? 297 THR A CB  1 
ATOM   2381  O OG1 . THR A 1 297 ? 15.833  -7.713  -52.949 1.00 74.37  ? 297 THR A OG1 1 
ATOM   2382  C CG2 . THR A 1 297 ? 15.008  -5.458  -53.315 1.00 71.00  ? 297 THR A CG2 1 
ATOM   2383  N N   . LYS A 1 298 ? 12.622  -9.140  -53.763 1.00 75.45  ? 298 LYS A N   1 
ATOM   2384  C CA  . LYS A 1 298 ? 12.287  -10.516 -54.106 1.00 79.74  ? 298 LYS A CA  1 
ATOM   2385  C C   . LYS A 1 298 ? 13.501  -11.427 -53.906 1.00 83.85  ? 298 LYS A C   1 
ATOM   2386  O O   . LYS A 1 298 ? 13.379  -12.513 -53.314 1.00 71.68  ? 298 LYS A O   1 
ATOM   2387  C CB  . LYS A 1 298 ? 11.743  -10.571 -55.538 1.00 90.63  ? 298 LYS A CB  1 
ATOM   2388  C CG  . LYS A 1 298 ? 10.223  -10.503 -55.650 1.00 101.52 ? 298 LYS A CG  1 
ATOM   2389  C CD  . LYS A 1 298 ? 9.704   -9.659  -56.799 1.00 107.00 ? 298 LYS A CD  1 
ATOM   2390  C CE  . LYS A 1 298 ? 9.826   -8.170  -56.531 1.00 107.99 ? 298 LYS A CE  1 
ATOM   2391  N NZ  . LYS A 1 298 ? 9.154   -7.371  -57.584 1.00 98.35  ? 298 LYS A NZ  1 
ATOM   2392  N N   . GLU A 1 299 ? 14.663  -10.931 -54.366 1.00 84.85  ? 299 GLU A N   1 
ATOM   2393  C CA  . GLU A 1 299 ? 15.924  -11.665 -54.377 1.00 96.82  ? 299 GLU A CA  1 
ATOM   2394  C C   . GLU A 1 299 ? 16.399  -11.930 -52.953 1.00 79.41  ? 299 GLU A C   1 
ATOM   2395  O O   . GLU A 1 299 ? 16.726  -13.067 -52.619 1.00 79.20  ? 299 GLU A O   1 
ATOM   2396  C CB  . GLU A 1 299 ? 17.034  -10.891 -55.105 1.00 107.13 ? 299 GLU A CB  1 
ATOM   2397  C CG  . GLU A 1 299 ? 16.783  -10.689 -56.589 1.00 109.73 ? 299 GLU A CG  1 
ATOM   2398  C CD  . GLU A 1 299 ? 15.551  -9.859  -56.913 1.00 104.96 ? 299 GLU A CD  1 
ATOM   2399  O OE1 . GLU A 1 299 ? 14.658  -10.381 -57.600 1.00 95.91  ? 299 GLU A OE1 1 
ATOM   2400  O OE2 . GLU A 1 299 ? 15.479  -8.703  -56.451 1.00 104.34 ? 299 GLU A OE2 1 
ATOM   2401  N N   . GLN A 1 300 ? 16.457  -10.861 -52.146 1.00 67.73  ? 300 GLN A N   1 
ATOM   2402  C CA  . GLN A 1 300 ? 16.852  -10.952 -50.745 1.00 77.48  ? 300 GLN A CA  1 
ATOM   2403  C C   . GLN A 1 300 ? 16.000  -11.980 -49.988 1.00 73.11  ? 300 GLN A C   1 
ATOM   2404  O O   . GLN A 1 300 ? 16.529  -12.789 -49.220 1.00 64.23  ? 300 GLN A O   1 
ATOM   2405  C CB  . GLN A 1 300 ? 16.761  -9.568  -50.093 1.00 79.70  ? 300 GLN A CB  1 
ATOM   2406  C CG  . GLN A 1 300 ? 17.838  -8.588  -50.563 1.00 79.19  ? 300 GLN A CG  1 
ATOM   2407  C CD  . GLN A 1 300 ? 17.631  -7.173  -50.057 1.00 81.21  ? 300 GLN A CD  1 
ATOM   2408  O OE1 . GLN A 1 300 ? 16.575  -6.560  -50.228 1.00 71.01  ? 300 GLN A OE1 1 
ATOM   2409  N NE2 . GLN A 1 300 ? 18.658  -6.622  -49.431 1.00 70.58  ? 300 GLN A NE2 1 
ATOM   2410  N N   . LEU A 1 301 ? 14.674  -11.929 -50.183 1.00 79.10  ? 301 LEU A N   1 
ATOM   2411  C CA  . LEU A 1 301 ? 13.761  -12.794 -49.449 1.00 75.13  ? 301 LEU A CA  1 
ATOM   2412  C C   . LEU A 1 301 ? 13.853  -14.216 -49.994 1.00 73.20  ? 301 LEU A C   1 
ATOM   2413  O O   . LEU A 1 301 ? 13.792  -15.163 -49.205 1.00 62.23  ? 301 LEU A O   1 
ATOM   2414  C CB  . LEU A 1 301 ? 12.319  -12.266 -49.526 1.00 75.88  ? 301 LEU A CB  1 
ATOM   2415  C CG  . LEU A 1 301 ? 11.275  -13.079 -48.744 1.00 73.54  ? 301 LEU A CG  1 
ATOM   2416  C CD1 . LEU A 1 301 ? 11.349  -12.792 -47.248 1.00 72.66  ? 301 LEU A CD1 1 
ATOM   2417  C CD2 . LEU A 1 301 ? 9.868   -12.814 -49.253 1.00 70.56  ? 301 LEU A CD2 1 
ATOM   2418  N N   . GLU A 1 302 ? 13.994  -14.350 -51.327 1.00 79.46  ? 302 GLU A N   1 
ATOM   2419  C CA  . GLU A 1 302 ? 14.174  -15.656 -51.950 1.00 78.50  ? 302 GLU A CA  1 
ATOM   2420  C C   . GLU A 1 302 ? 15.422  -16.328 -51.383 1.00 74.82  ? 302 GLU A C   1 
ATOM   2421  O O   . GLU A 1 302 ? 15.386  -17.500 -51.002 1.00 71.36  ? 302 GLU A O   1 
ATOM   2422  C CB  . GLU A 1 302 ? 14.306  -15.565 -53.472 1.00 91.62  ? 302 GLU A CB  1 
ATOM   2423  C CG  . GLU A 1 302 ? 14.496  -16.937 -54.131 1.00 95.81  ? 302 GLU A CG  1 
ATOM   2424  C CD  . GLU A 1 302 ? 14.680  -16.939 -55.640 1.00 92.47  ? 302 GLU A CD  1 
ATOM   2425  O OE1 . GLU A 1 302 ? 13.713  -17.289 -56.358 1.00 97.95  ? 302 GLU A OE1 1 
ATOM   2426  O OE2 . GLU A 1 302 ? 15.796  -16.616 -56.098 1.00 94.82  ? 302 GLU A OE2 1 
ATOM   2427  N N   . ARG A 1 303 ? 16.527  -15.573 -51.344 1.00 75.79  ? 303 ARG A N   1 
ATOM   2428  C CA  . ARG A 1 303 ? 17.755  -16.059 -50.738 1.00 75.54  ? 303 ARG A CA  1 
ATOM   2429  C C   . ARG A 1 303 ? 17.477  -16.449 -49.293 1.00 72.78  ? 303 ARG A C   1 
ATOM   2430  O O   . ARG A 1 303 ? 17.721  -17.599 -48.933 1.00 75.01  ? 303 ARG A O   1 
ATOM   2431  C CB  . ARG A 1 303 ? 18.887  -15.030 -50.796 1.00 74.64  ? 303 ARG A CB  1 
ATOM   2432  C CG  . ARG A 1 303 ? 19.506  -14.859 -52.176 1.00 85.46  ? 303 ARG A CG  1 
ATOM   2433  C CD  . ARG A 1 303 ? 20.978  -14.512 -52.054 1.00 94.14  ? 303 ARG A CD  1 
ATOM   2434  N NE  . ARG A 1 303 ? 21.250  -13.405 -51.137 1.00 84.52  ? 303 ARG A NE  1 
ATOM   2435  C CZ  . ARG A 1 303 ? 21.111  -12.120 -51.446 1.00 86.81  ? 303 ARG A CZ  1 
ATOM   2436  N NH1 . ARG A 1 303 ? 21.350  -11.192 -50.533 1.00 92.23  ? 303 ARG A NH1 1 
ATOM   2437  N NH2 . ARG A 1 303 ? 20.737  -11.768 -52.667 1.00 77.98  ? 303 ARG A NH2 1 
ATOM   2438  N N   . PHE A 1 304 ? 16.963  -15.489 -48.495 1.00 73.24  ? 304 PHE A N   1 
ATOM   2439  C CA  . PHE A 1 304 ? 16.740  -15.711 -47.071 1.00 66.49  ? 304 PHE A CA  1 
ATOM   2440  C C   . PHE A 1 304 ? 15.885  -16.962 -46.884 1.00 58.83  ? 304 PHE A C   1 
ATOM   2441  O O   . PHE A 1 304 ? 16.181  -17.790 -46.032 1.00 48.61  ? 304 PHE A O   1 
ATOM   2442  C CB  . PHE A 1 304 ? 16.100  -14.507 -46.367 1.00 67.38  ? 304 PHE A CB  1 
ATOM   2443  C CG  . PHE A 1 304 ? 16.001  -14.692 -44.873 1.00 61.18  ? 304 PHE A CG  1 
ATOM   2444  C CD1 . PHE A 1 304 ? 17.082  -14.427 -44.054 1.00 64.92  ? 304 PHE A CD1 1 
ATOM   2445  C CD2 . PHE A 1 304 ? 14.864  -15.239 -44.299 1.00 64.35  ? 304 PHE A CD2 1 
ATOM   2446  C CE1 . PHE A 1 304 ? 17.010  -14.653 -42.688 1.00 64.30  ? 304 PHE A CE1 1 
ATOM   2447  C CE2 . PHE A 1 304 ? 14.795  -15.470 -42.935 1.00 61.56  ? 304 PHE A CE2 1 
ATOM   2448  C CZ  . PHE A 1 304 ? 15.869  -15.174 -42.133 1.00 62.09  ? 304 PHE A CZ  1 
ATOM   2449  N N   . ALA A 1 305 ? 14.829  -17.112 -47.693 1.00 59.95  ? 305 ALA A N   1 
ATOM   2450  C CA  . ALA A 1 305 ? 13.998  -18.305 -47.609 1.00 66.00  ? 305 ALA A CA  1 
ATOM   2451  C C   . ALA A 1 305 ? 14.891  -19.554 -47.598 1.00 70.43  ? 305 ALA A C   1 
ATOM   2452  O O   . ALA A 1 305 ? 14.921  -20.307 -46.615 1.00 60.99  ? 305 ALA A O   1 
ATOM   2453  C CB  . ALA A 1 305 ? 12.986  -18.307 -48.738 1.00 60.60  ? 305 ALA A CB  1 
ATOM   2454  N N   . TRP A 1 306 ? 15.675  -19.705 -48.678 1.00 79.89  ? 306 TRP A N   1 
ATOM   2455  C CA  . TRP A 1 306 ? 16.522  -20.867 -48.914 1.00 75.77  ? 306 TRP A CA  1 
ATOM   2456  C C   . TRP A 1 306 ? 17.525  -21.093 -47.786 1.00 70.63  ? 306 TRP A C   1 
ATOM   2457  O O   . TRP A 1 306 ? 17.711  -22.229 -47.348 1.00 68.11  ? 306 TRP A O   1 
ATOM   2458  C CB  . TRP A 1 306 ? 17.218  -20.727 -50.265 1.00 75.16  ? 306 TRP A CB  1 
ATOM   2459  C CG  . TRP A 1 306 ? 16.383  -21.214 -51.409 1.00 70.87  ? 306 TRP A CG  1 
ATOM   2460  C CD1 . TRP A 1 306 ? 15.870  -20.490 -52.452 1.00 67.33  ? 306 TRP A CD1 1 
ATOM   2461  C CD2 . TRP A 1 306 ? 15.993  -22.580 -51.633 1.00 75.04  ? 306 TRP A CD2 1 
ATOM   2462  N NE1 . TRP A 1 306 ? 15.174  -21.311 -53.306 1.00 74.73  ? 306 TRP A NE1 1 
ATOM   2463  C CE2 . TRP A 1 306 ? 15.236  -22.600 -52.830 1.00 73.34  ? 306 TRP A CE2 1 
ATOM   2464  C CE3 . TRP A 1 306 ? 16.218  -23.781 -50.942 1.00 72.60  ? 306 TRP A CE3 1 
ATOM   2465  C CZ2 . TRP A 1 306 ? 14.710  -23.784 -53.344 1.00 69.54  ? 306 TRP A CZ2 1 
ATOM   2466  C CZ3 . TRP A 1 306 ? 15.681  -24.946 -51.446 1.00 72.30  ? 306 TRP A CZ3 1 
ATOM   2467  C CH2 . TRP A 1 306 ? 14.939  -24.942 -52.632 1.00 70.74  ? 306 TRP A CH2 1 
ATOM   2468  N N   . ASP A 1 307 ? 18.144  -20.018 -47.291 1.00 67.07  ? 307 ASP A N   1 
ATOM   2469  C CA  . ASP A 1 307 ? 19.134  -20.146 -46.228 1.00 82.07  ? 307 ASP A CA  1 
ATOM   2470  C C   . ASP A 1 307 ? 18.486  -20.608 -44.917 1.00 89.28  ? 307 ASP A C   1 
ATOM   2471  O O   . ASP A 1 307 ? 19.135  -21.277 -44.107 1.00 86.13  ? 307 ASP A O   1 
ATOM   2472  C CB  . ASP A 1 307 ? 19.948  -18.853 -46.084 1.00 80.54  ? 307 ASP A CB  1 
ATOM   2473  C CG  . ASP A 1 307 ? 20.858  -18.578 -47.275 1.00 85.56  ? 307 ASP A CG  1 
ATOM   2474  O OD1 . ASP A 1 307 ? 21.050  -19.503 -48.112 1.00 82.32  ? 307 ASP A OD1 1 
ATOM   2475  O OD2 . ASP A 1 307 ? 21.364  -17.443 -47.369 1.00 83.78  ? 307 ASP A OD2 1 
ATOM   2476  N N   . THR A 1 308 ? 17.205  -20.261 -44.707 1.00 104.38 ? 308 THR A N   1 
ATOM   2477  C CA  . THR A 1 308 ? 16.471  -20.685 -43.518 1.00 109.46 ? 308 THR A CA  1 
ATOM   2478  C C   . THR A 1 308 ? 16.153  -22.184 -43.626 1.00 95.34  ? 308 THR A C   1 
ATOM   2479  O O   . THR A 1 308 ? 16.450  -22.961 -42.706 1.00 83.84  ? 308 THR A O   1 
ATOM   2480  C CB  . THR A 1 308 ? 15.230  -19.799 -43.291 1.00 112.87 ? 308 THR A CB  1 
ATOM   2481  O OG1 . THR A 1 308 ? 15.597  -18.418 -43.232 1.00 109.54 ? 308 THR A OG1 1 
ATOM   2482  C CG2 . THR A 1 308 ? 14.488  -20.123 -42.011 1.00 119.12 ? 308 THR A CG2 1 
ATOM   2483  N N   . LEU A 1 309 ? 15.560  -22.578 -44.764 1.00 73.69  ? 309 LEU A N   1 
ATOM   2484  C CA  . LEU A 1 309 ? 15.225  -23.967 -45.039 1.00 84.96  ? 309 LEU A CA  1 
ATOM   2485  C C   . LEU A 1 309 ? 16.453  -24.877 -44.903 1.00 95.20  ? 309 LEU A C   1 
ATOM   2486  O O   . LEU A 1 309 ? 16.413  -25.864 -44.168 1.00 90.29  ? 309 LEU A O   1 
ATOM   2487  C CB  . LEU A 1 309 ? 14.615  -24.038 -46.442 1.00 80.69  ? 309 LEU A CB  1 
ATOM   2488  C CG  . LEU A 1 309 ? 13.169  -23.563 -46.505 1.00 74.07  ? 309 LEU A CG  1 
ATOM   2489  C CD1 . LEU A 1 309 ? 12.661  -23.488 -47.938 1.00 71.03  ? 309 LEU A CD1 1 
ATOM   2490  C CD2 . LEU A 1 309 ? 12.298  -24.485 -45.662 1.00 74.05  ? 309 LEU A CD2 1 
ATOM   2491  N N   . ASN A 1 310 ? 17.556  -24.523 -45.578 1.00 92.12  ? 310 ASN A N   1 
ATOM   2492  C CA  . ASN A 1 310 ? 18.723  -25.389 -45.629 1.00 81.33  ? 310 ASN A CA  1 
ATOM   2493  C C   . ASN A 1 310 ? 19.481  -25.337 -44.308 1.00 83.15  ? 310 ASN A C   1 
ATOM   2494  O O   . ASN A 1 310 ? 20.424  -26.101 -44.141 1.00 98.56  ? 310 ASN A O   1 
ATOM   2495  C CB  . ASN A 1 310 ? 19.633  -25.076 -46.819 1.00 68.48  ? 310 ASN A CB  1 
ATOM   2496  C CG  . ASN A 1 310 ? 18.999  -25.461 -48.140 1.00 78.47  ? 310 ASN A CG  1 
ATOM   2497  O OD1 . ASN A 1 310 ? 18.475  -26.567 -48.279 1.00 81.78  ? 310 ASN A OD1 1 
ATOM   2498  N ND2 . ASN A 1 310 ? 19.022  -24.559 -49.111 1.00 79.44  ? 310 ASN A ND2 1 
ATOM   2499  N N   . SER A 1 311 ? 19.076  -24.472 -43.366 1.00 75.72  ? 311 SER A N   1 
ATOM   2500  C CA  . SER A 1 311 ? 19.642  -24.537 -42.022 1.00 91.22  ? 311 SER A CA  1 
ATOM   2501  C C   . SER A 1 311 ? 18.691  -25.268 -41.065 1.00 90.69  ? 311 SER A C   1 
ATOM   2502  O O   . SER A 1 311 ? 18.856  -25.191 -39.842 1.00 65.97  ? 311 SER A O   1 
ATOM   2503  C CB  . SER A 1 311 ? 20.073  -23.167 -41.501 1.00 94.23  ? 311 SER A CB  1 
ATOM   2504  O OG  . SER A 1 311 ? 18.996  -22.247 -41.456 1.00 99.84  ? 311 SER A OG  1 
ATOM   2505  N N   . GLY A 1 312 ? 17.711  -25.991 -41.644 1.00 97.53  ? 312 GLY A N   1 
ATOM   2506  C CA  . GLY A 1 312 ? 16.824  -26.887 -40.909 1.00 99.88  ? 312 GLY A CA  1 
ATOM   2507  C C   . GLY A 1 312 ? 15.785  -26.149 -40.061 1.00 103.22 ? 312 GLY A C   1 
ATOM   2508  O O   . GLY A 1 312 ? 15.379  -26.634 -39.007 1.00 80.18  ? 312 GLY A O   1 
ATOM   2509  N N   . GLN A 1 313 ? 15.364  -24.965 -40.526 1.00 108.76 ? 313 GLN A N   1 
ATOM   2510  C CA  . GLN A 1 313 ? 14.427  -24.144 -39.778 1.00 103.16 ? 313 GLN A CA  1 
ATOM   2511  C C   . GLN A 1 313 ? 13.075  -24.169 -40.486 1.00 97.62  ? 313 GLN A C   1 
ATOM   2512  O O   . GLN A 1 313 ? 12.992  -24.485 -41.679 1.00 86.92  ? 313 GLN A O   1 
ATOM   2513  C CB  . GLN A 1 313 ? 14.955  -22.714 -39.627 1.00 99.86  ? 313 GLN A CB  1 
ATOM   2514  C CG  . GLN A 1 313 ? 16.247  -22.605 -38.826 1.00 106.69 ? 313 GLN A CG  1 
ATOM   2515  C CD  . GLN A 1 313 ? 16.056  -22.744 -37.334 1.00 105.34 ? 313 GLN A CD  1 
ATOM   2516  O OE1 . GLN A 1 313 ? 16.001  -21.747 -36.618 1.00 100.62 ? 313 GLN A OE1 1 
ATOM   2517  N NE2 . GLN A 1 313 ? 15.963  -23.976 -36.852 1.00 97.10  ? 313 GLN A NE2 1 
ATOM   2518  N N   . VAL A 1 314 ? 12.031  -23.838 -39.715 1.00 91.81  ? 314 VAL A N   1 
ATOM   2519  C CA  . VAL A 1 314 ? 10.671  -23.709 -40.220 1.00 97.62  ? 314 VAL A CA  1 
ATOM   2520  C C   . VAL A 1 314 ? 10.452  -22.284 -40.750 1.00 78.97  ? 314 VAL A C   1 
ATOM   2521  O O   . VAL A 1 314 ? 10.886  -21.332 -40.107 1.00 80.49  ? 314 VAL A O   1 
ATOM   2522  C CB  . VAL A 1 314 ? 9.644   -24.091 -39.127 1.00 109.45 ? 314 VAL A CB  1 
ATOM   2523  C CG1 . VAL A 1 314 ? 9.768   -25.564 -38.747 1.00 109.29 ? 314 VAL A CG1 1 
ATOM   2524  C CG2 . VAL A 1 314 ? 9.717   -23.206 -37.879 1.00 103.16 ? 314 VAL A CG2 1 
ATOM   2525  N N   . ILE A 1 315 ? 9.823   -22.149 -41.936 1.00 68.87  ? 315 ILE A N   1 
ATOM   2526  C CA  . ILE A 1 315 ? 9.251   -20.883 -42.384 1.00 71.68  ? 315 ILE A CA  1 
ATOM   2527  C C   . ILE A 1 315 ? 7.847   -20.718 -41.787 1.00 78.02  ? 315 ILE A C   1 
ATOM   2528  O O   . ILE A 1 315 ? 6.884   -21.277 -42.321 1.00 74.06  ? 315 ILE A O   1 
ATOM   2529  C CB  . ILE A 1 315 ? 9.189   -20.775 -43.919 1.00 69.41  ? 315 ILE A CB  1 
ATOM   2530  C CG1 . ILE A 1 315 ? 10.580  -20.645 -44.544 1.00 70.13  ? 315 ILE A CG1 1 
ATOM   2531  C CG2 . ILE A 1 315 ? 8.291   -19.611 -44.322 1.00 71.50  ? 315 ILE A CG2 1 
ATOM   2532  C CD1 . ILE A 1 315 ? 10.554  -20.438 -46.037 1.00 68.87  ? 315 ILE A CD1 1 
ATOM   2533  N N   . PRO A 1 316 ? 7.642   -19.877 -40.740 1.00 71.06  ? 316 PRO A N   1 
ATOM   2534  C CA  . PRO A 1 316 ? 6.376   -19.877 -40.014 1.00 63.81  ? 316 PRO A CA  1 
ATOM   2535  C C   . PRO A 1 316 ? 5.280   -19.293 -40.907 1.00 52.03  ? 316 PRO A C   1 
ATOM   2536  O O   . PRO A 1 316 ? 5.514   -18.366 -41.667 1.00 54.60  ? 316 PRO A O   1 
ATOM   2537  C CB  . PRO A 1 316 ? 6.630   -19.038 -38.747 1.00 70.91  ? 316 PRO A CB  1 
ATOM   2538  C CG  . PRO A 1 316 ? 8.076   -18.562 -38.843 1.00 74.38  ? 316 PRO A CG  1 
ATOM   2539  C CD  . PRO A 1 316 ? 8.530   -18.802 -40.269 1.00 70.60  ? 316 PRO A CD  1 
ATOM   2540  N N   . GLY A 1 317 ? 4.096   -19.901 -40.846 1.00 51.97  ? 317 GLY A N   1 
ATOM   2541  C CA  . GLY A 1 317 ? 2.905   -19.377 -41.479 1.00 54.36  ? 317 GLY A CA  1 
ATOM   2542  C C   . GLY A 1 317 ? 2.520   -20.145 -42.733 1.00 53.49  ? 317 GLY A C   1 
ATOM   2543  O O   . GLY A 1 317 ? 1.453   -19.891 -43.289 1.00 56.93  ? 317 GLY A O   1 
ATOM   2544  N N   . TYR A 1 318 ? 3.417   -21.045 -43.166 1.00 69.88  ? 318 TYR A N   1 
ATOM   2545  C CA  . TYR A 1 318 ? 3.256   -21.849 -44.369 1.00 70.32  ? 318 TYR A CA  1 
ATOM   2546  C C   . TYR A 1 318 ? 3.249   -23.339 -44.009 1.00 74.06  ? 318 TYR A C   1 
ATOM   2547  O O   . TYR A 1 318 ? 3.913   -23.763 -43.063 1.00 78.76  ? 318 TYR A O   1 
ATOM   2548  C CB  . TYR A 1 318 ? 4.346   -21.448 -45.362 1.00 62.54  ? 318 TYR A CB  1 
ATOM   2549  C CG  . TYR A 1 318 ? 4.140   -20.077 -45.962 1.00 60.10  ? 318 TYR A CG  1 
ATOM   2550  C CD1 . TYR A 1 318 ? 4.352   -18.915 -45.234 1.00 65.11  ? 318 TYR A CD1 1 
ATOM   2551  C CD2 . TYR A 1 318 ? 3.706   -19.942 -47.269 1.00 54.93  ? 318 TYR A CD2 1 
ATOM   2552  C CE1 . TYR A 1 318 ? 4.135   -17.658 -45.787 1.00 57.46  ? 318 TYR A CE1 1 
ATOM   2553  C CE2 . TYR A 1 318 ? 3.482   -18.700 -47.839 1.00 62.75  ? 318 TYR A CE2 1 
ATOM   2554  C CZ  . TYR A 1 318 ? 3.702   -17.551 -47.097 1.00 62.35  ? 318 TYR A CZ  1 
ATOM   2555  O OH  . TYR A 1 318 ? 3.492   -16.349 -47.728 1.00 55.19  ? 318 TYR A OH  1 
ATOM   2556  N N   . GLY A 1 319 ? 2.431   -24.120 -44.730 1.00 88.51  ? 319 GLY A N   1 
ATOM   2557  C CA  . GLY A 1 319 ? 2.207   -25.525 -44.413 1.00 82.55  ? 319 GLY A CA  1 
ATOM   2558  C C   . GLY A 1 319 ? 1.185   -25.733 -43.295 1.00 77.20  ? 319 GLY A C   1 
ATOM   2559  O O   . GLY A 1 319 ? 1.089   -24.940 -42.363 1.00 97.36  ? 319 GLY A O   1 
ATOM   2560  N N   . HIS A 1 320 ? 0.451   -26.844 -43.372 1.00 92.07  ? 320 HIS A N   1 
ATOM   2561  C CA  . HIS A 1 320 ? -0.539  -27.202 -42.364 1.00 97.07  ? 320 HIS A CA  1 
ATOM   2562  C C   . HIS A 1 320 ? -0.557  -28.724 -42.203 1.00 92.31  ? 320 HIS A C   1 
ATOM   2563  O O   . HIS A 1 320 ? -0.102  -29.449 -43.091 1.00 79.14  ? 320 HIS A O   1 
ATOM   2564  C CB  . HIS A 1 320 ? -1.926  -26.667 -42.761 1.00 96.03  ? 320 HIS A CB  1 
ATOM   2565  C CG  . HIS A 1 320 ? -2.943  -26.593 -41.656 1.00 83.32  ? 320 HIS A CG  1 
ATOM   2566  N ND1 . HIS A 1 320 ? -4.065  -27.392 -41.617 1.00 74.30  ? 320 HIS A ND1 1 
ATOM   2567  C CD2 . HIS A 1 320 ? -3.020  -25.808 -40.566 1.00 85.27  ? 320 HIS A CD2 1 
ATOM   2568  C CE1 . HIS A 1 320 ? -4.776  -27.105 -40.528 1.00 76.22  ? 320 HIS A CE1 1 
ATOM   2569  N NE2 . HIS A 1 320 ? -4.169  -26.131 -39.885 1.00 76.17  ? 320 HIS A NE2 1 
ATOM   2570  N N   . ALA A 1 321 ? -1.143  -29.181 -41.085 1.00 91.65  ? 321 ALA A N   1 
ATOM   2571  C CA  . ALA A 1 321 ? -1.319  -30.594 -40.775 1.00 96.58  ? 321 ALA A CA  1 
ATOM   2572  C C   . ALA A 1 321 ? -2.509  -31.228 -41.515 1.00 103.20 ? 321 ALA A C   1 
ATOM   2573  O O   . ALA A 1 321 ? -2.782  -32.408 -41.273 1.00 93.47  ? 321 ALA A O   1 
ATOM   2574  C CB  . ALA A 1 321 ? -1.476  -30.752 -39.276 1.00 87.18  ? 321 ALA A CB  1 
ATOM   2575  N N   . VAL A 1 322 ? -3.186  -30.461 -42.391 1.00 107.63 ? 322 VAL A N   1 
ATOM   2576  C CA  . VAL A 1 322 ? -4.305  -31.007 -43.230 1.00 100.60 ? 322 VAL A CA  1 
ATOM   2577  C C   . VAL A 1 322 ? -4.512  -30.151 -44.491 1.00 96.93  ? 322 VAL A C   1 
ATOM   2578  O O   . VAL A 1 322 ? -4.646  -30.748 -45.574 1.00 86.18  ? 322 VAL A O   1 
ATOM   2579  C CB  . VAL A 1 322 ? -5.613  -31.174 -42.428 1.00 110.76 ? 322 VAL A CB  1 
ATOM   2580  C CG1 . VAL A 1 322 ? -5.795  -30.127 -41.346 1.00 114.77 ? 322 VAL A CG1 1 
ATOM   2581  C CG2 . VAL A 1 322 ? -6.843  -31.258 -43.317 1.00 112.59 ? 322 VAL A CG2 1 
ATOM   2582  N N   . LEU A 1 323 ? -4.529  -28.817 -44.374 1.00 102.92 ? 323 LEU A N   1 
ATOM   2583  C CA  . LEU A 1 323 ? -4.731  -27.912 -45.512 1.00 97.97  ? 323 LEU A CA  1 
ATOM   2584  C C   . LEU A 1 323 ? -3.733  -28.247 -46.617 1.00 85.14  ? 323 LEU A C   1 
ATOM   2585  O O   . LEU A 1 323 ? -2.634  -28.698 -46.304 1.00 76.67  ? 323 LEU A O   1 
ATOM   2586  C CB  . LEU A 1 323 ? -4.538  -26.443 -45.089 1.00 103.57 ? 323 LEU A CB  1 
ATOM   2587  C CG  . LEU A 1 323 ? -5.775  -25.568 -44.839 1.00 98.72  ? 323 LEU A CG  1 
ATOM   2588  C CD1 . LEU A 1 323 ? -6.987  -26.010 -45.650 1.00 92.40  ? 323 LEU A CD1 1 
ATOM   2589  C CD2 . LEU A 1 323 ? -6.117  -25.496 -43.363 1.00 91.39  ? 323 LEU A CD2 1 
ATOM   2590  N N   . ARG A 1 324 ? -4.094  -27.983 -47.886 1.00 81.24  ? 324 ARG A N   1 
ATOM   2591  C CA  . ARG A 1 324 ? -3.244  -28.406 -48.991 1.00 90.37  ? 324 ARG A CA  1 
ATOM   2592  C C   . ARG A 1 324 ? -3.091  -27.326 -50.070 1.00 85.19  ? 324 ARG A C   1 
ATOM   2593  O O   . ARG A 1 324 ? -2.102  -27.370 -50.791 1.00 93.87  ? 324 ARG A O   1 
ATOM   2594  C CB  . ARG A 1 324 ? -3.776  -29.734 -49.543 1.00 103.48 ? 324 ARG A CB  1 
ATOM   2595  C CG  . ARG A 1 324 ? -2.726  -30.801 -49.847 1.00 102.91 ? 324 ARG A CG  1 
ATOM   2596  C CD  . ARG A 1 324 ? -1.678  -31.133 -48.787 1.00 99.92  ? 324 ARG A CD  1 
ATOM   2597  N NE  . ARG A 1 324 ? -2.078  -31.063 -47.380 1.00 102.87 ? 324 ARG A NE  1 
ATOM   2598  C CZ  . ARG A 1 324 ? -1.406  -31.607 -46.359 1.00 97.94  ? 324 ARG A CZ  1 
ATOM   2599  N NH1 . ARG A 1 324 ? -1.414  -31.018 -45.174 1.00 95.69  ? 324 ARG A NH1 1 
ATOM   2600  N NH2 . ARG A 1 324 ? -0.620  -32.653 -46.546 1.00 86.92  ? 324 ARG A NH2 1 
ATOM   2601  N N   . VAL A 1 325 ? -3.983  -26.335 -50.074 1.00 92.60  ? 325 VAL A N   1 
ATOM   2602  C CA  . VAL A 1 325 ? -3.824  -25.156 -50.978 1.00 98.99  ? 325 VAL A CA  1 
ATOM   2603  C C   . VAL A 1 325 ? -3.832  -23.904 -50.088 1.00 94.89  ? 325 VAL A C   1 
ATOM   2604  O O   . VAL A 1 325 ? -3.575  -24.046 -48.883 1.00 90.42  ? 325 VAL A O   1 
ATOM   2605  C CB  . VAL A 1 325 ? -4.907  -25.097 -52.068 1.00 92.91  ? 325 VAL A CB  1 
ATOM   2606  C CG1 . VAL A 1 325 ? -4.613  -26.066 -53.200 1.00 90.23  ? 325 VAL A CG1 1 
ATOM   2607  C CG2 . VAL A 1 325 ? -6.291  -25.344 -51.492 1.00 101.43 ? 325 VAL A CG2 1 
ATOM   2608  N N   . THR A 1 326 ? -4.124  -22.728 -50.643 1.00 83.35  ? 326 THR A N   1 
ATOM   2609  C CA  . THR A 1 326 ? -4.079  -21.492 -49.868 1.00 86.21  ? 326 THR A CA  1 
ATOM   2610  C C   . THR A 1 326 ? -5.276  -21.457 -48.909 1.00 72.99  ? 326 THR A C   1 
ATOM   2611  O O   . THR A 1 326 ? -6.423  -21.684 -49.310 1.00 65.06  ? 326 THR A O   1 
ATOM   2612  C CB  . THR A 1 326 ? -3.966  -20.254 -50.779 1.00 88.68  ? 326 THR A CB  1 
ATOM   2613  O OG1 . THR A 1 326 ? -2.774  -20.361 -51.559 1.00 90.04  ? 326 THR A OG1 1 
ATOM   2614  C CG2 . THR A 1 326 ? -3.894  -18.939 -50.029 1.00 94.23  ? 326 THR A CG2 1 
ATOM   2615  N N   . ASP A 1 327 ? -4.988  -21.189 -47.626 1.00 65.38  ? 327 ASP A N   1 
ATOM   2616  C CA  . ASP A 1 327 ? -6.013  -21.124 -46.595 1.00 54.06  ? 327 ASP A CA  1 
ATOM   2617  C C   . ASP A 1 327 ? -6.925  -19.942 -46.907 1.00 45.78  ? 327 ASP A C   1 
ATOM   2618  O O   . ASP A 1 327 ? -6.483  -18.799 -46.917 1.00 49.96  ? 327 ASP A O   1 
ATOM   2619  C CB  . ASP A 1 327 ? -5.367  -21.074 -45.206 1.00 54.69  ? 327 ASP A CB  1 
ATOM   2620  C CG  . ASP A 1 327 ? -6.359  -21.080 -44.049 1.00 57.07  ? 327 ASP A CG  1 
ATOM   2621  O OD1 . ASP A 1 327 ? -7.578  -20.875 -44.295 1.00 58.46  ? 327 ASP A OD1 1 
ATOM   2622  O OD2 . ASP A 1 327 ? -5.924  -21.322 -42.918 1.00 49.36  ? 327 ASP A OD2 1 
ATOM   2623  N N   . PRO A 1 328 ? -8.230  -20.158 -47.176 1.00 53.04  ? 328 PRO A N   1 
ATOM   2624  C CA  . PRO A 1 328 ? -9.150  -19.048 -47.438 1.00 52.25  ? 328 PRO A CA  1 
ATOM   2625  C C   . PRO A 1 328 ? -9.294  -18.036 -46.284 1.00 57.90  ? 328 PRO A C   1 
ATOM   2626  O O   . PRO A 1 328 ? -9.748  -16.900 -46.485 1.00 53.10  ? 328 PRO A O   1 
ATOM   2627  C CB  . PRO A 1 328 ? -10.487 -19.754 -47.744 1.00 52.71  ? 328 PRO A CB  1 
ATOM   2628  C CG  . PRO A 1 328 ? -10.381 -21.094 -47.080 1.00 55.34  ? 328 PRO A CG  1 
ATOM   2629  C CD  . PRO A 1 328 ? -8.910  -21.468 -47.189 1.00 58.59  ? 328 PRO A CD  1 
ATOM   2630  N N   . ARG A 1 329 ? -8.892  -18.436 -45.069 1.00 55.99  ? 329 ARG A N   1 
ATOM   2631  C CA  . ARG A 1 329 ? -8.785  -17.507 -43.946 1.00 52.80  ? 329 ARG A CA  1 
ATOM   2632  C C   . ARG A 1 329 ? -7.647  -16.512 -44.188 1.00 55.21  ? 329 ARG A C   1 
ATOM   2633  O O   . ARG A 1 329 ? -7.788  -15.331 -43.836 1.00 49.50  ? 329 ARG A O   1 
ATOM   2634  C CB  . ARG A 1 329 ? -8.623  -18.268 -42.624 1.00 50.22  ? 329 ARG A CB  1 
ATOM   2635  C CG  . ARG A 1 329 ? -9.803  -19.184 -42.314 1.00 49.81  ? 329 ARG A CG  1 
ATOM   2636  C CD  . ARG A 1 329 ? -9.632  -20.095 -41.121 1.00 41.95  ? 329 ARG A CD  1 
ATOM   2637  N NE  . ARG A 1 329 ? -8.428  -20.882 -41.226 1.00 45.89  ? 329 ARG A NE  1 
ATOM   2638  C CZ  . ARG A 1 329 ? -7.916  -21.624 -40.252 1.00 52.16  ? 329 ARG A CZ  1 
ATOM   2639  N NH1 . ARG A 1 329 ? -8.540  -21.751 -39.085 1.00 44.85  ? 329 ARG A NH1 1 
ATOM   2640  N NH2 . ARG A 1 329 ? -6.769  -22.242 -40.466 1.00 57.46  ? 329 ARG A NH2 1 
ATOM   2641  N N   . TYR A 1 330 ? -6.558  -16.965 -44.845 1.00 54.56  ? 330 TYR A N   1 
ATOM   2642  C CA  . TYR A 1 330 ? -5.489  -16.067 -45.270 1.00 52.50  ? 330 TYR A CA  1 
ATOM   2643  C C   . TYR A 1 330 ? -6.003  -15.059 -46.300 1.00 49.88  ? 330 TYR A C   1 
ATOM   2644  O O   . TYR A 1 330 ? -5.643  -13.883 -46.274 1.00 58.30  ? 330 TYR A O   1 
ATOM   2645  C CB  . TYR A 1 330 ? -4.261  -16.835 -45.774 1.00 54.48  ? 330 TYR A CB  1 
ATOM   2646  C CG  . TYR A 1 330 ? -3.087  -15.986 -46.214 1.00 47.19  ? 330 TYR A CG  1 
ATOM   2647  C CD1 . TYR A 1 330 ? -3.010  -15.457 -47.489 1.00 51.30  ? 330 TYR A CD1 1 
ATOM   2648  C CD2 . TYR A 1 330 ? -2.047  -15.709 -45.345 1.00 51.60  ? 330 TYR A CD2 1 
ATOM   2649  C CE1 . TYR A 1 330 ? -1.928  -14.687 -47.892 1.00 57.29  ? 330 TYR A CE1 1 
ATOM   2650  C CE2 . TYR A 1 330 ? -0.951  -14.955 -45.728 1.00 52.47  ? 330 TYR A CE2 1 
ATOM   2651  C CZ  . TYR A 1 330 ? -0.881  -14.443 -47.014 1.00 57.19  ? 330 TYR A CZ  1 
ATOM   2652  O OH  . TYR A 1 330 ? 0.221   -13.668 -47.379 1.00 49.80  ? 330 TYR A OH  1 
ATOM   2653  N N   . VAL A 1 331 ? -6.847  -15.494 -47.218 1.00 54.08  ? 331 VAL A N   1 
ATOM   2654  C CA  . VAL A 1 331 ? -7.197  -14.611 -48.326 1.00 64.96  ? 331 VAL A CA  1 
ATOM   2655  C C   . VAL A 1 331 ? -8.121  -13.505 -47.821 1.00 61.09  ? 331 VAL A C   1 
ATOM   2656  O O   . VAL A 1 331 ? -8.141  -12.406 -48.388 1.00 52.93  ? 331 VAL A O   1 
ATOM   2657  C CB  . VAL A 1 331 ? -7.847  -15.370 -49.508 1.00 75.77  ? 331 VAL A CB  1 
ATOM   2658  C CG1 . VAL A 1 331 ? -8.125  -14.447 -50.693 1.00 67.03  ? 331 VAL A CG1 1 
ATOM   2659  C CG2 . VAL A 1 331 ? -7.013  -16.569 -49.942 1.00 76.07  ? 331 VAL A CG2 1 
ATOM   2660  N N   . ALA A 1 332 ? -8.914  -13.814 -46.778 1.00 54.99  ? 332 ALA A N   1 
ATOM   2661  C CA  . ALA A 1 332 ? -9.828  -12.825 -46.231 1.00 53.17  ? 332 ALA A CA  1 
ATOM   2662  C C   . ALA A 1 332 ? -9.034  -11.703 -45.570 1.00 47.19  ? 332 ALA A C   1 
ATOM   2663  O O   . ALA A 1 332 ? -9.318  -10.524 -45.774 1.00 51.46  ? 332 ALA A O   1 
ATOM   2664  C CB  . ALA A 1 332 ? -10.822 -13.464 -45.286 1.00 57.35  ? 332 ALA A CB  1 
ATOM   2665  N N   . GLN A 1 333 ? -7.966  -12.073 -44.872 1.00 45.64  ? 333 GLN A N   1 
ATOM   2666  C CA  . GLN A 1 333 ? -7.137  -11.092 -44.191 1.00 50.37  ? 333 GLN A CA  1 
ATOM   2667  C C   . GLN A 1 333 ? -6.392  -10.195 -45.191 1.00 56.07  ? 333 GLN A C   1 
ATOM   2668  O O   . GLN A 1 333 ? -6.312  -8.961  -44.999 1.00 49.84  ? 333 GLN A O   1 
ATOM   2669  C CB  . GLN A 1 333 ? -6.250  -11.850 -43.209 1.00 47.40  ? 333 GLN A CB  1 
ATOM   2670  C CG  . GLN A 1 333 ? -7.070  -12.364 -42.041 1.00 50.34  ? 333 GLN A CG  1 
ATOM   2671  C CD  . GLN A 1 333 ? -6.265  -13.193 -41.083 1.00 53.66  ? 333 GLN A CD  1 
ATOM   2672  O OE1 . GLN A 1 333 ? -5.933  -12.746 -39.993 1.00 53.10  ? 333 GLN A OE1 1 
ATOM   2673  N NE2 . GLN A 1 333 ? -5.944  -14.409 -41.500 1.00 56.21  ? 333 GLN A NE2 1 
ATOM   2674  N N   . ARG A 1 334 ? -5.855  -10.819 -46.251 1.00 52.32  ? 334 ARG A N   1 
ATOM   2675  C CA  . ARG A 1 334 ? -5.140  -10.095 -47.296 1.00 56.61  ? 334 ARG A CA  1 
ATOM   2676  C C   . ARG A 1 334 ? -6.064  -9.051  -47.918 1.00 51.22  ? 334 ARG A C   1 
ATOM   2677  O O   . ARG A 1 334 ? -5.679  -7.887  -48.095 1.00 53.48  ? 334 ARG A O   1 
ATOM   2678  C CB  . ARG A 1 334 ? -4.593  -11.097 -48.320 1.00 65.37  ? 334 ARG A CB  1 
ATOM   2679  C CG  . ARG A 1 334 ? -4.049  -10.482 -49.601 1.00 73.48  ? 334 ARG A CG  1 
ATOM   2680  C CD  . ARG A 1 334 ? -3.308  -11.502 -50.458 1.00 73.21  ? 334 ARG A CD  1 
ATOM   2681  N NE  . ARG A 1 334 ? -2.787  -10.948 -51.703 1.00 75.67  ? 334 ARG A NE  1 
ATOM   2682  C CZ  . ARG A 1 334 ? -1.768  -10.097 -51.807 1.00 69.54  ? 334 ARG A CZ  1 
ATOM   2683  N NH1 . ARG A 1 334 ? -1.113  -9.693  -50.731 1.00 69.50  ? 334 ARG A NH1 1 
ATOM   2684  N NH2 . ARG A 1 334 ? -1.406  -9.653  -52.999 1.00 68.02  ? 334 ARG A NH2 1 
ATOM   2685  N N   . ASP A 1 335 ? -7.318  -9.451  -48.177 1.00 51.39  ? 335 ASP A N   1 
ATOM   2686  C CA  . ASP A 1 335 ? -8.313  -8.531  -48.730 1.00 54.32  ? 335 ASP A CA  1 
ATOM   2687  C C   . ASP A 1 335 ? -8.447  -7.319  -47.810 1.00 52.78  ? 335 ASP A C   1 
ATOM   2688  O O   . ASP A 1 335 ? -8.298  -6.176  -48.263 1.00 54.59  ? 335 ASP A O   1 
ATOM   2689  C CB  . ASP A 1 335 ? -9.664  -9.217  -48.979 1.00 50.95  ? 335 ASP A CB  1 
ATOM   2690  C CG  . ASP A 1 335 ? -10.645 -8.405  -49.816 1.00 67.15  ? 335 ASP A CG  1 
ATOM   2691  O OD1 . ASP A 1 335 ? -10.410 -8.270  -51.063 1.00 66.93  ? 335 ASP A OD1 1 
ATOM   2692  O OD2 . ASP A 1 335 ? -11.649 -7.903  -49.222 1.00 66.30  ? 335 ASP A OD2 1 
ATOM   2693  N N   . PHE A 1 336 ? -8.702  -7.603  -46.518 1.00 49.13  ? 336 PHE A N   1 
ATOM   2694  C CA  . PHE A 1 336 ? -8.833  -6.580  -45.495 1.00 52.82  ? 336 PHE A CA  1 
ATOM   2695  C C   . PHE A 1 336 ? -7.625  -5.643  -45.520 1.00 50.98  ? 336 PHE A C   1 
ATOM   2696  O O   . PHE A 1 336 ? -7.806  -4.426  -45.482 1.00 53.47  ? 336 PHE A O   1 
ATOM   2697  C CB  . PHE A 1 336 ? -9.013  -7.224  -44.114 1.00 54.66  ? 336 PHE A CB  1 
ATOM   2698  C CG  . PHE A 1 336 ? -9.308  -6.238  -43.015 1.00 43.79  ? 336 PHE A CG  1 
ATOM   2699  C CD1 . PHE A 1 336 ? -8.286  -5.501  -42.423 1.00 47.54  ? 336 PHE A CD1 1 
ATOM   2700  C CD2 . PHE A 1 336 ? -10.606 -6.022  -42.590 1.00 43.45  ? 336 PHE A CD2 1 
ATOM   2701  C CE1 . PHE A 1 336 ? -8.559  -4.566  -41.432 1.00 47.52  ? 336 PHE A CE1 1 
ATOM   2702  C CE2 . PHE A 1 336 ? -10.884 -5.077  -41.604 1.00 46.42  ? 336 PHE A CE2 1 
ATOM   2703  C CZ  . PHE A 1 336 ? -9.856  -4.372  -41.004 1.00 46.62  ? 336 PHE A CZ  1 
ATOM   2704  N N   . ALA A 1 337 ? -6.408  -6.214  -45.588 1.00 49.26  ? 337 ALA A N   1 
ATOM   2705  C CA  . ALA A 1 337 ? -5.186  -5.429  -45.522 1.00 52.00  ? 337 ALA A CA  1 
ATOM   2706  C C   . ALA A 1 337 ? -4.994  -4.555  -46.772 1.00 57.75  ? 337 ALA A C   1 
ATOM   2707  O O   . ALA A 1 337 ? -4.598  -3.395  -46.642 1.00 60.19  ? 337 ALA A O   1 
ATOM   2708  C CB  . ALA A 1 337 ? -4.015  -6.354  -45.322 1.00 52.31  ? 337 ALA A CB  1 
ATOM   2709  N N   . LEU A 1 338 ? -5.244  -5.102  -47.978 1.00 55.26  ? 338 LEU A N   1 
ATOM   2710  C CA  . LEU A 1 338 ? -5.183  -4.296  -49.196 1.00 65.93  ? 338 LEU A CA  1 
ATOM   2711  C C   . LEU A 1 338 ? -6.190  -3.153  -49.101 1.00 66.20  ? 338 LEU A C   1 
ATOM   2712  O O   . LEU A 1 338 ? -5.909  -2.027  -49.510 1.00 64.93  ? 338 LEU A O   1 
ATOM   2713  C CB  . LEU A 1 338 ? -5.473  -5.136  -50.450 1.00 58.93  ? 338 LEU A CB  1 
ATOM   2714  C CG  . LEU A 1 338 ? -4.442  -6.210  -50.802 1.00 61.01  ? 338 LEU A CG  1 
ATOM   2715  C CD1 . LEU A 1 338 ? -4.911  -7.046  -51.983 1.00 58.55  ? 338 LEU A CD1 1 
ATOM   2716  C CD2 . LEU A 1 338 ? -3.069  -5.612  -51.096 1.00 65.29  ? 338 LEU A CD2 1 
ATOM   2717  N N   . LYS A 1 339 ? -7.356  -3.450  -48.525 1.00 59.14  ? 339 LYS A N   1 
ATOM   2718  C CA  . LYS A 1 339 ? -8.424  -2.472  -48.440 1.00 62.96  ? 339 LYS A CA  1 
ATOM   2719  C C   . LYS A 1 339 ? -8.105  -1.380  -47.411 1.00 65.79  ? 339 LYS A C   1 
ATOM   2720  O O   . LYS A 1 339 ? -8.440  -0.220  -47.637 1.00 63.47  ? 339 LYS A O   1 
ATOM   2721  C CB  . LYS A 1 339 ? -9.721  -3.238  -48.146 1.00 76.68  ? 339 LYS A CB  1 
ATOM   2722  C CG  . LYS A 1 339 ? -10.983 -2.401  -47.962 1.00 86.19  ? 339 LYS A CG  1 
ATOM   2723  C CD  . LYS A 1 339 ? -12.238 -3.245  -48.087 1.00 95.63  ? 339 LYS A CD  1 
ATOM   2724  C CE  . LYS A 1 339 ? -13.488 -2.590  -47.541 1.00 99.37  ? 339 LYS A CE  1 
ATOM   2725  N NZ  . LYS A 1 339 ? -14.625 -3.539  -47.560 1.00 99.02  ? 339 LYS A NZ  1 
ATOM   2726  N N   . HIS A 1 340 ? -7.477  -1.737  -46.272 1.00 64.99  ? 340 HIS A N   1 
ATOM   2727  C CA  . HIS A 1 340 ? -7.407  -0.837  -45.128 1.00 61.57  ? 340 HIS A CA  1 
ATOM   2728  C C   . HIS A 1 340 ? -5.990  -0.385  -44.789 1.00 56.53  ? 340 HIS A C   1 
ATOM   2729  O O   . HIS A 1 340 ? -5.836  0.675   -44.206 1.00 55.75  ? 340 HIS A O   1 
ATOM   2730  C CB  . HIS A 1 340 ? -8.055  -1.461  -43.893 1.00 63.51  ? 340 HIS A CB  1 
ATOM   2731  C CG  . HIS A 1 340 ? -9.505  -1.703  -44.088 1.00 60.55  ? 340 HIS A CG  1 
ATOM   2732  N ND1 . HIS A 1 340 ? -10.386 -0.666  -44.247 1.00 58.74  ? 340 HIS A ND1 1 
ATOM   2733  C CD2 . HIS A 1 340 ? -10.230 -2.820  -44.146 1.00 66.12  ? 340 HIS A CD2 1 
ATOM   2734  C CE1 . HIS A 1 340 ? -11.608 -1.153  -44.390 1.00 65.25  ? 340 HIS A CE1 1 
ATOM   2735  N NE2 . HIS A 1 340 ? -11.537 -2.463  -44.332 1.00 68.08  ? 340 HIS A NE2 1 
ATOM   2736  N N   . LEU A 1 341 ? -4.945  -1.143  -45.135 1.00 60.30  ? 341 LEU A N   1 
ATOM   2737  C CA  . LEU A 1 341 ? -3.607  -0.724  -44.746 1.00 56.91  ? 341 LEU A CA  1 
ATOM   2738  C C   . LEU A 1 341 ? -2.584  -1.186  -45.775 1.00 61.65  ? 341 LEU A C   1 
ATOM   2739  O O   . LEU A 1 341 ? -1.528  -1.727  -45.439 1.00 51.51  ? 341 LEU A O   1 
ATOM   2740  C CB  . LEU A 1 341 ? -3.311  -1.233  -43.331 1.00 57.01  ? 341 LEU A CB  1 
ATOM   2741  C CG  . LEU A 1 341 ? -3.390  -2.743  -43.124 1.00 56.06  ? 341 LEU A CG  1 
ATOM   2742  C CD1 . LEU A 1 341 ? -2.050  -3.317  -42.669 1.00 51.81  ? 341 LEU A CD1 1 
ATOM   2743  C CD2 . LEU A 1 341 ? -4.489  -3.097  -42.132 1.00 64.36  ? 341 LEU A CD2 1 
ATOM   2744  N N   . PRO A 1 342 ? -2.823  -0.862  -47.064 1.00 65.94  ? 342 PRO A N   1 
ATOM   2745  C CA  . PRO A 1 342 ? -1.947  -1.311  -48.148 1.00 61.90  ? 342 PRO A CA  1 
ATOM   2746  C C   . PRO A 1 342 ? -0.499  -0.858  -48.005 1.00 62.39  ? 342 PRO A C   1 
ATOM   2747  O O   . PRO A 1 342 ? 0.392   -1.511  -48.549 1.00 63.94  ? 342 PRO A O   1 
ATOM   2748  C CB  . PRO A 1 342 ? -2.573  -0.715  -49.415 1.00 68.13  ? 342 PRO A CB  1 
ATOM   2749  C CG  . PRO A 1 342 ? -3.458  0.424   -48.911 1.00 66.45  ? 342 PRO A CG  1 
ATOM   2750  C CD  . PRO A 1 342 ? -3.920  -0.004  -47.533 1.00 65.00  ? 342 PRO A CD  1 
ATOM   2751  N N   . ASP A 1 343 ? -0.260  0.201   -47.214 1.00 59.93  ? 343 ASP A N   1 
ATOM   2752  C CA  . ASP A 1 343 ? 1.062   0.803   -47.134 1.00 67.40  ? 343 ASP A CA  1 
ATOM   2753  C C   . ASP A 1 343 ? 1.776   0.488   -45.822 1.00 64.20  ? 343 ASP A C   1 
ATOM   2754  O O   . ASP A 1 343 ? 2.860   1.019   -45.596 1.00 61.77  ? 343 ASP A O   1 
ATOM   2755  C CB  . ASP A 1 343 ? 0.966   2.311   -47.385 1.00 75.33  ? 343 ASP A CB  1 
ATOM   2756  C CG  . ASP A 1 343 ? 0.666   2.602   -48.849 1.00 83.44  ? 343 ASP A CG  1 
ATOM   2757  O OD1 . ASP A 1 343 ? 1.572   2.356   -49.679 1.00 91.08  ? 343 ASP A OD1 1 
ATOM   2758  O OD2 . ASP A 1 343 ? -0.491  2.988   -49.163 1.00 71.32  ? 343 ASP A OD2 1 
ATOM   2759  N N   . ASP A 1 344 ? 1.192   -0.363  -44.968 1.00 63.78  ? 344 ASP A N   1 
ATOM   2760  C CA  . ASP A 1 344 ? 1.880   -0.795  -43.760 1.00 63.21  ? 344 ASP A CA  1 
ATOM   2761  C C   . ASP A 1 344 ? 3.118   -1.579  -44.177 1.00 54.48  ? 344 ASP A C   1 
ATOM   2762  O O   . ASP A 1 344 ? 3.049   -2.461  -45.024 1.00 54.49  ? 344 ASP A O   1 
ATOM   2763  C CB  . ASP A 1 344 ? 0.986   -1.625  -42.825 1.00 68.37  ? 344 ASP A CB  1 
ATOM   2764  C CG  . ASP A 1 344 ? 1.635   -2.038  -41.501 1.00 65.90  ? 344 ASP A CG  1 
ATOM   2765  O OD1 . ASP A 1 344 ? 2.469   -2.971  -41.517 1.00 72.50  ? 344 ASP A OD1 1 
ATOM   2766  O OD2 . ASP A 1 344 ? 1.335   -1.403  -40.460 1.00 58.78  ? 344 ASP A OD2 1 
ATOM   2767  N N   . GLU A 1 345 ? 4.247   -1.225  -43.572 1.00 59.49  ? 345 GLU A N   1 
ATOM   2768  C CA  . GLU A 1 345 ? 5.527   -1.824  -43.897 1.00 65.53  ? 345 GLU A CA  1 
ATOM   2769  C C   . GLU A 1 345 ? 5.491   -3.342  -43.672 1.00 65.49  ? 345 GLU A C   1 
ATOM   2770  O O   . GLU A 1 345 ? 5.866   -4.112  -44.562 1.00 66.40  ? 345 GLU A O   1 
ATOM   2771  C CB  . GLU A 1 345 ? 6.613   -1.136  -43.070 1.00 77.03  ? 345 GLU A CB  1 
ATOM   2772  C CG  . GLU A 1 345 ? 6.880   0.321   -43.463 1.00 90.45  ? 345 GLU A CG  1 
ATOM   2773  C CD  . GLU A 1 345 ? 7.692   0.560   -44.736 1.00 92.55  ? 345 GLU A CD  1 
ATOM   2774  O OE1 . GLU A 1 345 ? 7.089   0.586   -45.829 1.00 85.72  ? 345 GLU A OE1 1 
ATOM   2775  O OE2 . GLU A 1 345 ? 8.939   0.711   -44.640 1.00 85.24  ? 345 GLU A OE2 1 
ATOM   2776  N N   . LEU A 1 346 ? 5.029   -3.781  -42.495 1.00 55.00  ? 346 LEU A N   1 
ATOM   2777  C CA  . LEU A 1 346 ? 5.071   -5.193  -42.144 1.00 52.80  ? 346 LEU A CA  1 
ATOM   2778  C C   . LEU A 1 346 ? 4.126   -5.994  -43.039 1.00 55.76  ? 346 LEU A C   1 
ATOM   2779  O O   . LEU A 1 346 ? 4.472   -7.105  -43.441 1.00 51.61  ? 346 LEU A O   1 
ATOM   2780  C CB  . LEU A 1 346 ? 4.722   -5.397  -40.663 1.00 52.39  ? 346 LEU A CB  1 
ATOM   2781  C CG  . LEU A 1 346 ? 5.595   -4.639  -39.663 1.00 53.67  ? 346 LEU A CG  1 
ATOM   2782  C CD1 . LEU A 1 346 ? 5.203   -5.003  -38.244 1.00 54.21  ? 346 LEU A CD1 1 
ATOM   2783  C CD2 . LEU A 1 346 ? 7.080   -4.908  -39.895 1.00 59.03  ? 346 LEU A CD2 1 
ATOM   2784  N N   . PHE A 1 347 ? 2.943   -5.432  -43.336 1.00 55.02  ? 347 PHE A N   1 
ATOM   2785  C CA  . PHE A 1 347 ? 2.037   -6.006  -44.318 1.00 58.69  ? 347 PHE A CA  1 
ATOM   2786  C C   . PHE A 1 347 ? 2.729   -6.239  -45.667 1.00 63.34  ? 347 PHE A C   1 
ATOM   2787  O O   . PHE A 1 347 ? 2.484   -7.267  -46.308 1.00 53.63  ? 347 PHE A O   1 
ATOM   2788  C CB  . PHE A 1 347 ? 0.820   -5.111  -44.578 1.00 58.77  ? 347 PHE A CB  1 
ATOM   2789  C CG  . PHE A 1 347 ? -0.003  -5.574  -45.756 1.00 55.77  ? 347 PHE A CG  1 
ATOM   2790  C CD1 . PHE A 1 347 ? -0.492  -6.874  -45.806 1.00 59.29  ? 347 PHE A CD1 1 
ATOM   2791  C CD2 . PHE A 1 347 ? -0.248  -4.740  -46.840 1.00 60.82  ? 347 PHE A CD2 1 
ATOM   2792  C CE1 . PHE A 1 347 ? -1.225  -7.321  -46.899 1.00 58.28  ? 347 PHE A CE1 1 
ATOM   2793  C CE2 . PHE A 1 347 ? -1.008  -5.178  -47.920 1.00 58.13  ? 347 PHE A CE2 1 
ATOM   2794  C CZ  . PHE A 1 347 ? -1.488  -6.471  -47.948 1.00 57.19  ? 347 PHE A CZ  1 
ATOM   2795  N N   . LYS A 1 348 ? 3.575   -5.284  -46.100 1.00 60.50  ? 348 LYS A N   1 
ATOM   2796  C CA  . LYS A 1 348 ? 4.222   -5.363  -47.407 1.00 69.81  ? 348 LYS A CA  1 
ATOM   2797  C C   . LYS A 1 348 ? 5.183   -6.551  -47.448 1.00 67.08  ? 348 LYS A C   1 
ATOM   2798  O O   . LYS A 1 348 ? 5.324   -7.186  -48.488 1.00 65.38  ? 348 LYS A O   1 
ATOM   2799  C CB  . LYS A 1 348 ? 4.944   -4.060  -47.777 1.00 72.19  ? 348 LYS A CB  1 
ATOM   2800  C CG  . LYS A 1 348 ? 4.015   -2.928  -48.182 1.00 80.16  ? 348 LYS A CG  1 
ATOM   2801  C CD  . LYS A 1 348 ? 4.702   -1.732  -48.815 1.00 95.91  ? 348 LYS A CD  1 
ATOM   2802  C CE  . LYS A 1 348 ? 3.718   -0.849  -49.559 1.00 100.80 ? 348 LYS A CE  1 
ATOM   2803  N NZ  . LYS A 1 348 ? 4.255   0.503   -49.840 1.00 98.95  ? 348 LYS A NZ  1 
ATOM   2804  N N   . ILE A 1 349 ? 5.825   -6.855  -46.316 1.00 57.35  ? 349 ILE A N   1 
ATOM   2805  C CA  . ILE A 1 349 ? 6.626   -8.059  -46.199 1.00 53.82  ? 349 ILE A CA  1 
ATOM   2806  C C   . ILE A 1 349 ? 5.742   -9.308  -46.296 1.00 54.72  ? 349 ILE A C   1 
ATOM   2807  O O   . ILE A 1 349 ? 6.112   -10.300 -46.932 1.00 61.52  ? 349 ILE A O   1 
ATOM   2808  C CB  . ILE A 1 349 ? 7.448   -7.986  -44.899 1.00 48.59  ? 349 ILE A CB  1 
ATOM   2809  C CG1 . ILE A 1 349 ? 8.384   -6.779  -44.941 1.00 50.64  ? 349 ILE A CG1 1 
ATOM   2810  C CG2 . ILE A 1 349 ? 8.213   -9.259  -44.655 1.00 52.11  ? 349 ILE A CG2 1 
ATOM   2811  C CD1 . ILE A 1 349 ? 9.273   -6.647  -43.735 1.00 53.17  ? 349 ILE A CD1 1 
ATOM   2812  N N   . VAL A 1 350 ? 4.580   -9.276  -45.635 1.00 59.42  ? 350 VAL A N   1 
ATOM   2813  C CA  . VAL A 1 350 ? 3.653   -10.402 -45.653 1.00 57.38  ? 350 VAL A CA  1 
ATOM   2814  C C   . VAL A 1 350 ? 3.222   -10.658 -47.094 1.00 54.03  ? 350 VAL A C   1 
ATOM   2815  O O   . VAL A 1 350 ? 3.280   -11.780 -47.556 1.00 52.30  ? 350 VAL A O   1 
ATOM   2816  C CB  . VAL A 1 350 ? 2.431   -10.161 -44.742 1.00 49.43  ? 350 VAL A CB  1 
ATOM   2817  C CG1 . VAL A 1 350 ? 1.228   -10.980 -45.168 1.00 47.88  ? 350 VAL A CG1 1 
ATOM   2818  C CG2 . VAL A 1 350 ? 2.763   -10.427 -43.281 1.00 52.37  ? 350 VAL A CG2 1 
ATOM   2819  N N   . SER A 1 351 ? 2.760   -9.601  -47.767 1.00 58.89  ? 351 SER A N   1 
ATOM   2820  C CA  . SER A 1 351 ? 2.422   -9.650  -49.177 1.00 65.99  ? 351 SER A CA  1 
ATOM   2821  C C   . SER A 1 351 ? 3.570   -10.293 -49.966 1.00 66.07  ? 351 SER A C   1 
ATOM   2822  O O   . SER A 1 351 ? 3.370   -11.277 -50.675 1.00 62.95  ? 351 SER A O   1 
ATOM   2823  C CB  . SER A 1 351 ? 2.079   -8.263  -49.681 1.00 66.00  ? 351 SER A CB  1 
ATOM   2824  O OG  . SER A 1 351 ? 1.131   -8.329  -50.738 1.00 68.35  ? 351 SER A OG  1 
ATOM   2825  N N   . LEU A 1 352 ? 4.787   -9.767  -49.789 1.00 72.59  ? 352 LEU A N   1 
ATOM   2826  C CA  . LEU A 1 352 ? 5.932   -10.226 -50.551 1.00 76.95  ? 352 LEU A CA  1 
ATOM   2827  C C   . LEU A 1 352 ? 6.202   -11.695 -50.253 1.00 78.13  ? 352 LEU A C   1 
ATOM   2828  O O   . LEU A 1 352 ? 6.572   -12.432 -51.158 1.00 84.52  ? 352 LEU A O   1 
ATOM   2829  C CB  . LEU A 1 352 ? 7.168   -9.380  -50.239 1.00 85.54  ? 352 LEU A CB  1 
ATOM   2830  C CG  . LEU A 1 352 ? 8.320   -9.554  -51.232 1.00 88.60  ? 352 LEU A CG  1 
ATOM   2831  C CD1 . LEU A 1 352 ? 8.030   -8.807  -52.531 1.00 83.03  ? 352 LEU A CD1 1 
ATOM   2832  C CD2 . LEU A 1 352 ? 9.639   -9.097  -50.631 1.00 89.53  ? 352 LEU A CD2 1 
ATOM   2833  N N   . CYS A 1 353 ? 5.993   -12.127 -49.003 1.00 73.16  ? 353 CYS A N   1 
ATOM   2834  C CA  . CYS A 1 353 ? 6.088   -13.546 -48.705 1.00 62.90  ? 353 CYS A CA  1 
ATOM   2835  C C   . CYS A 1 353 ? 5.113   -14.342 -49.572 1.00 64.04  ? 353 CYS A C   1 
ATOM   2836  O O   . CYS A 1 353 ? 5.408   -15.486 -49.907 1.00 60.98  ? 353 CYS A O   1 
ATOM   2837  C CB  . CYS A 1 353 ? 5.839   -13.850 -47.235 1.00 63.20  ? 353 CYS A CB  1 
ATOM   2838  S SG  . CYS A 1 353 ? 7.266   -13.491 -46.188 1.00 64.86  ? 353 CYS A SG  1 
ATOM   2839  N N   . TYR A 1 354 ? 3.965   -13.741 -49.923 1.00 62.86  ? 354 TYR A N   1 
ATOM   2840  C CA  . TYR A 1 354 ? 2.919   -14.440 -50.658 1.00 69.55  ? 354 TYR A CA  1 
ATOM   2841  C C   . TYR A 1 354 ? 3.404   -14.837 -52.057 1.00 77.35  ? 354 TYR A C   1 
ATOM   2842  O O   . TYR A 1 354 ? 3.152   -15.967 -52.484 1.00 67.60  ? 354 TYR A O   1 
ATOM   2843  C CB  . TYR A 1 354 ? 1.635   -13.603 -50.726 1.00 63.99  ? 354 TYR A CB  1 
ATOM   2844  C CG  . TYR A 1 354 ? 0.363   -14.342 -51.084 1.00 59.52  ? 354 TYR A CG  1 
ATOM   2845  C CD1 . TYR A 1 354 ? 0.210   -15.707 -50.878 1.00 55.65  ? 354 TYR A CD1 1 
ATOM   2846  C CD2 . TYR A 1 354 ? -0.703  -13.657 -51.655 1.00 62.29  ? 354 TYR A CD2 1 
ATOM   2847  C CE1 . TYR A 1 354 ? -0.968  -16.359 -51.214 1.00 61.66  ? 354 TYR A CE1 1 
ATOM   2848  C CE2 . TYR A 1 354 ? -1.887  -14.292 -52.002 1.00 57.40  ? 354 TYR A CE2 1 
ATOM   2849  C CZ  . TYR A 1 354 ? -2.020  -15.647 -51.766 1.00 60.73  ? 354 TYR A CZ  1 
ATOM   2850  O OH  . TYR A 1 354 ? -3.190  -16.273 -52.104 1.00 70.54  ? 354 TYR A OH  1 
ATOM   2851  N N   . GLU A 1 355 ? 4.128   -13.933 -52.746 1.00 84.61  ? 355 GLU A N   1 
ATOM   2852  C CA  . GLU A 1 355 ? 4.661   -14.203 -54.084 1.00 87.68  ? 355 GLU A CA  1 
ATOM   2853  C C   . GLU A 1 355 ? 5.785   -15.248 -54.047 1.00 80.83  ? 355 GLU A C   1 
ATOM   2854  O O   . GLU A 1 355 ? 5.748   -16.254 -54.758 1.00 81.63  ? 355 GLU A O   1 
ATOM   2855  C CB  . GLU A 1 355 ? 5.203   -12.917 -54.709 1.00 88.71  ? 355 GLU A CB  1 
ATOM   2856  C CG  . GLU A 1 355 ? 4.135   -11.877 -54.997 1.00 104.60 ? 355 GLU A CG  1 
ATOM   2857  C CD  . GLU A 1 355 ? 4.667   -10.466 -55.205 1.00 121.24 ? 355 GLU A CD  1 
ATOM   2858  O OE1 . GLU A 1 355 ? 3.847   -9.533  -55.276 1.00 121.46 ? 355 GLU A OE1 1 
ATOM   2859  O OE2 . GLU A 1 355 ? 5.905   -10.299 -55.287 1.00 137.57 ? 355 GLU A OE2 1 
ATOM   2860  N N   . VAL A 1 356 ? 6.760   -15.016 -53.165 1.00 73.03  ? 356 VAL A N   1 
ATOM   2861  C CA  . VAL A 1 356 ? 8.051   -15.679 -53.206 1.00 70.67  ? 356 VAL A CA  1 
ATOM   2862  C C   . VAL A 1 356 ? 7.999   -17.054 -52.530 1.00 81.04  ? 356 VAL A C   1 
ATOM   2863  O O   . VAL A 1 356 ? 8.466   -18.035 -53.109 1.00 88.45  ? 356 VAL A O   1 
ATOM   2864  C CB  . VAL A 1 356 ? 9.116   -14.774 -52.551 1.00 64.31  ? 356 VAL A CB  1 
ATOM   2865  C CG1 . VAL A 1 356 ? 10.459  -15.473 -52.417 1.00 60.15  ? 356 VAL A CG1 1 
ATOM   2866  C CG2 . VAL A 1 356 ? 9.265   -13.439 -53.271 1.00 62.55  ? 356 VAL A CG2 1 
ATOM   2867  N N   . ILE A 1 357 ? 7.452   -17.122 -51.306 1.00 76.00  ? 357 ILE A N   1 
ATOM   2868  C CA  . ILE A 1 357 ? 7.679   -18.249 -50.408 1.00 78.87  ? 357 ILE A CA  1 
ATOM   2869  C C   . ILE A 1 357 ? 7.013   -19.536 -50.900 1.00 82.41  ? 357 ILE A C   1 
ATOM   2870  O O   . ILE A 1 357 ? 7.550   -20.607 -50.619 1.00 89.64  ? 357 ILE A O   1 
ATOM   2871  C CB  . ILE A 1 357 ? 7.248   -17.934 -48.958 1.00 71.36  ? 357 ILE A CB  1 
ATOM   2872  C CG1 . ILE A 1 357 ? 8.007   -16.744 -48.366 1.00 69.19  ? 357 ILE A CG1 1 
ATOM   2873  C CG2 . ILE A 1 357 ? 7.410   -19.166 -48.070 1.00 75.44  ? 357 ILE A CG2 1 
ATOM   2874  C CD1 . ILE A 1 357 ? 9.431   -17.060 -47.992 1.00 63.40  ? 357 ILE A CD1 1 
ATOM   2875  N N   . PRO A 1 358 ? 5.839   -19.526 -51.584 1.00 86.89  ? 358 PRO A N   1 
ATOM   2876  C CA  . PRO A 1 358 ? 5.277   -20.758 -52.154 1.00 107.27 ? 358 PRO A CA  1 
ATOM   2877  C C   . PRO A 1 358 ? 6.221   -21.557 -53.067 1.00 120.96 ? 358 PRO A C   1 
ATOM   2878  O O   . PRO A 1 358 ? 6.433   -22.754 -52.847 1.00 113.49 ? 358 PRO A O   1 
ATOM   2879  C CB  . PRO A 1 358 ? 4.066   -20.270 -52.973 1.00 106.34 ? 358 PRO A CB  1 
ATOM   2880  C CG  . PRO A 1 358 ? 3.684   -18.947 -52.348 1.00 99.29  ? 358 PRO A CG  1 
ATOM   2881  C CD  . PRO A 1 358 ? 4.984   -18.357 -51.843 1.00 92.74  ? 358 PRO A CD  1 
ATOM   2882  N N   . GLU A 1 359 ? 6.796   -20.876 -54.075 1.00 121.29 ? 359 GLU A N   1 
ATOM   2883  C CA  . GLU A 1 359 ? 7.601   -21.500 -55.120 1.00 119.08 ? 359 GLU A CA  1 
ATOM   2884  C C   . GLU A 1 359 ? 8.885   -22.107 -54.549 1.00 107.52 ? 359 GLU A C   1 
ATOM   2885  O O   . GLU A 1 359 ? 9.316   -23.160 -55.012 1.00 113.57 ? 359 GLU A O   1 
ATOM   2886  C CB  . GLU A 1 359 ? 7.895   -20.472 -56.214 1.00 120.21 ? 359 GLU A CB  1 
ATOM   2887  C CG  . GLU A 1 359 ? 6.677   -20.175 -57.076 1.00 128.83 ? 359 GLU A CG  1 
ATOM   2888  C CD  . GLU A 1 359 ? 6.609   -18.806 -57.733 1.00 128.49 ? 359 GLU A CD  1 
ATOM   2889  O OE1 . GLU A 1 359 ? 7.419   -17.914 -57.371 1.00 107.48 ? 359 GLU A OE1 1 
ATOM   2890  O OE2 . GLU A 1 359 ? 5.733   -18.635 -58.608 1.00 118.92 ? 359 GLU A OE2 1 
ATOM   2891  N N   . VAL A 1 360 ? 9.472   -21.439 -53.545 1.00 93.30  ? 360 VAL A N   1 
ATOM   2892  C CA  . VAL A 1 360 ? 10.641  -21.912 -52.810 1.00 95.37  ? 360 VAL A CA  1 
ATOM   2893  C C   . VAL A 1 360 ? 10.350  -23.230 -52.075 1.00 108.01 ? 360 VAL A C   1 
ATOM   2894  O O   . VAL A 1 360 ? 11.196  -24.127 -52.051 1.00 107.20 ? 360 VAL A O   1 
ATOM   2895  C CB  . VAL A 1 360 ? 11.123  -20.829 -51.815 1.00 91.46  ? 360 VAL A CB  1 
ATOM   2896  C CG1 . VAL A 1 360 ? 12.113  -21.363 -50.784 1.00 81.56  ? 360 VAL A CG1 1 
ATOM   2897  C CG2 . VAL A 1 360 ? 11.691  -19.604 -52.529 1.00 92.01  ? 360 VAL A CG2 1 
ATOM   2898  N N   . LEU A 1 361 ? 9.176   -23.324 -51.431 1.00 119.50 ? 361 LEU A N   1 
ATOM   2899  C CA  . LEU A 1 361 ? 8.858   -24.436 -50.541 1.00 119.63 ? 361 LEU A CA  1 
ATOM   2900  C C   . LEU A 1 361 ? 8.474   -25.690 -51.336 1.00 113.75 ? 361 LEU A C   1 
ATOM   2901  O O   . LEU A 1 361 ? 8.564   -26.798 -50.796 1.00 79.01  ? 361 LEU A O   1 
ATOM   2902  C CB  . LEU A 1 361 ? 7.732   -24.022 -49.577 1.00 115.27 ? 361 LEU A CB  1 
ATOM   2903  C CG  . LEU A 1 361 ? 8.163   -23.441 -48.226 1.00 100.16 ? 361 LEU A CG  1 
ATOM   2904  C CD1 . LEU A 1 361 ? 6.991   -22.766 -47.527 1.00 99.94  ? 361 LEU A CD1 1 
ATOM   2905  C CD2 . LEU A 1 361 ? 8.748   -24.518 -47.319 1.00 92.83  ? 361 LEU A CD2 1 
ATOM   2906  N N   . LYS A 1 362 ? 8.032   -25.500 -52.596 1.00 105.95 ? 362 LYS A N   1 
ATOM   2907  C CA  . LYS A 1 362 ? 7.762   -26.595 -53.523 1.00 109.34 ? 362 LYS A CA  1 
ATOM   2908  C C   . LYS A 1 362 ? 9.051   -27.348 -53.853 1.00 98.93  ? 362 LYS A C   1 
ATOM   2909  O O   . LYS A 1 362 ? 9.091   -28.577 -53.789 1.00 80.11  ? 362 LYS A O   1 
ATOM   2910  C CB  . LYS A 1 362 ? 7.111   -26.080 -54.814 1.00 107.13 ? 362 LYS A CB  1 
ATOM   2911  C CG  . LYS A 1 362 ? 5.591   -26.016 -54.775 1.00 107.76 ? 362 LYS A CG  1 
ATOM   2912  C CD  . LYS A 1 362 ? 4.969   -25.384 -55.994 1.00 110.24 ? 362 LYS A CD  1 
ATOM   2913  C CE  . LYS A 1 362 ? 3.460   -25.478 -55.970 1.00 111.07 ? 362 LYS A CE  1 
ATOM   2914  N NZ  . LYS A 1 362 ? 2.855   -24.771 -57.119 1.00 110.58 ? 362 LYS A NZ  1 
ATOM   2915  N N   . LYS A 1 363 ? 10.096  -26.582 -54.184 1.00 87.86  ? 363 LYS A N   1 
ATOM   2916  C CA  . LYS A 1 363 ? 11.366  -27.130 -54.609 1.00 84.65  ? 363 LYS A CA  1 
ATOM   2917  C C   . LYS A 1 363 ? 12.053  -27.828 -53.440 1.00 84.64  ? 363 LYS A C   1 
ATOM   2918  O O   . LYS A 1 363 ? 12.512  -28.951 -53.604 1.00 88.63  ? 363 LYS A O   1 
ATOM   2919  C CB  . LYS A 1 363 ? 12.201  -26.015 -55.229 1.00 86.94  ? 363 LYS A CB  1 
ATOM   2920  C CG  . LYS A 1 363 ? 11.534  -25.357 -56.431 1.00 92.05  ? 363 LYS A CG  1 
ATOM   2921  C CD  . LYS A 1 363 ? 12.347  -24.221 -56.995 1.00 93.38  ? 363 LYS A CD  1 
ATOM   2922  C CE  . LYS A 1 363 ? 11.622  -23.446 -58.068 1.00 93.34  ? 363 LYS A CE  1 
ATOM   2923  N NZ  . LYS A 1 363 ? 12.525  -22.435 -58.660 1.00 98.08  ? 363 LYS A NZ  1 
ATOM   2924  N N   . HIS A 1 364 ? 12.086  -27.195 -52.261 1.00 91.92  ? 364 HIS A N   1 
ATOM   2925  C CA  . HIS A 1 364 ? 12.654  -27.819 -51.068 1.00 98.63  ? 364 HIS A CA  1 
ATOM   2926  C C   . HIS A 1 364 ? 11.993  -29.175 -50.782 1.00 111.83 ? 364 HIS A C   1 
ATOM   2927  O O   . HIS A 1 364 ? 12.658  -30.103 -50.322 1.00 106.96 ? 364 HIS A O   1 
ATOM   2928  C CB  . HIS A 1 364 ? 12.574  -26.872 -49.867 1.00 90.77  ? 364 HIS A CB  1 
ATOM   2929  C CG  . HIS A 1 364 ? 13.177  -27.412 -48.608 1.00 96.37  ? 364 HIS A CG  1 
ATOM   2930  N ND1 . HIS A 1 364 ? 12.451  -27.599 -47.445 1.00 97.30  ? 364 HIS A ND1 1 
ATOM   2931  C CD2 . HIS A 1 364 ? 14.436  -27.789 -48.324 1.00 98.79  ? 364 HIS A CD2 1 
ATOM   2932  C CE1 . HIS A 1 364 ? 13.255  -28.059 -46.491 1.00 98.15  ? 364 HIS A CE1 1 
ATOM   2933  N NE2 . HIS A 1 364 ? 14.467  -28.188 -47.005 1.00 102.72 ? 364 HIS A NE2 1 
ATOM   2934  N N   . GLY A 1 365 ? 10.670  -29.263 -50.993 1.00 123.06 ? 365 GLY A N   1 
ATOM   2935  C CA  . GLY A 1 365 ? 9.966   -30.530 -51.153 1.00 116.30 ? 365 GLY A CA  1 
ATOM   2936  C C   . GLY A 1 365 ? 9.775   -31.346 -49.869 1.00 110.26 ? 365 GLY A C   1 
ATOM   2937  O O   . GLY A 1 365 ? 9.450   -32.528 -49.953 1.00 97.19  ? 365 GLY A O   1 
ATOM   2938  N N   . LYS A 1 366 ? 9.959   -30.732 -48.689 1.00 114.29 ? 366 LYS A N   1 
ATOM   2939  C CA  . LYS A 1 366 ? 9.678   -31.404 -47.425 1.00 111.96 ? 366 LYS A CA  1 
ATOM   2940  C C   . LYS A 1 366 ? 8.251   -31.088 -46.982 1.00 113.31 ? 366 LYS A C   1 
ATOM   2941  O O   . LYS A 1 366 ? 7.533   -31.992 -46.560 1.00 103.70 ? 366 LYS A O   1 
ATOM   2942  C CB  . LYS A 1 366 ? 10.695  -31.031 -46.339 1.00 106.01 ? 366 LYS A CB  1 
ATOM   2943  C CG  . LYS A 1 366 ? 12.131  -31.384 -46.695 1.00 116.50 ? 366 LYS A CG  1 
ATOM   2944  C CD  . LYS A 1 366 ? 13.076  -31.535 -45.528 1.00 118.09 ? 366 LYS A CD  1 
ATOM   2945  C CE  . LYS A 1 366 ? 14.513  -31.665 -45.993 1.00 121.33 ? 366 LYS A CE  1 
ATOM   2946  N NZ  . LYS A 1 366 ? 15.420  -32.072 -44.896 1.00 123.69 ? 366 LYS A NZ  1 
ATOM   2947  N N   . ALA A 1 367 ? 7.853   -29.811 -47.090 1.00 113.53 ? 367 ALA A N   1 
ATOM   2948  C CA  . ALA A 1 367 ? 6.501   -29.373 -46.759 1.00 111.11 ? 367 ALA A CA  1 
ATOM   2949  C C   . ALA A 1 367 ? 5.471   -30.057 -47.664 1.00 102.84 ? 367 ALA A C   1 
ATOM   2950  O O   . ALA A 1 367 ? 5.592   -30.031 -48.892 1.00 79.74  ? 367 ALA A O   1 
ATOM   2951  C CB  . ALA A 1 367 ? 6.403   -27.864 -46.860 1.00 109.29 ? 367 ALA A CB  1 
ATOM   2952  N N   . LYS A 1 368 ? 4.452   -30.662 -47.031 1.00 97.12  ? 368 LYS A N   1 
ATOM   2953  C CA  . LYS A 1 368 ? 3.337   -31.269 -47.742 1.00 89.81  ? 368 LYS A CA  1 
ATOM   2954  C C   . LYS A 1 368 ? 2.411   -30.164 -48.275 1.00 89.99  ? 368 LYS A C   1 
ATOM   2955  O O   . LYS A 1 368 ? 1.904   -30.294 -49.391 1.00 81.10  ? 368 LYS A O   1 
ATOM   2956  C CB  . LYS A 1 368 ? 2.648   -32.295 -46.831 1.00 77.99  ? 368 LYS A CB  1 
ATOM   2957  N N   . ASN A 1 369 ? 2.227   -29.066 -47.505 1.00 98.92  ? 369 ASN A N   1 
ATOM   2958  C CA  . ASN A 1 369 ? 1.474   -27.885 -47.950 1.00 105.41 ? 369 ASN A CA  1 
ATOM   2959  C C   . ASN A 1 369 ? 2.407   -26.682 -48.160 1.00 92.83  ? 369 ASN A C   1 
ATOM   2960  O O   . ASN A 1 369 ? 2.944   -26.133 -47.191 1.00 83.81  ? 369 ASN A O   1 
ATOM   2961  C CB  . ASN A 1 369 ? 0.353   -27.499 -46.971 1.00 100.76 ? 369 ASN A CB  1 
ATOM   2962  C CG  . ASN A 1 369 ? -0.416  -26.249 -47.374 1.00 98.59  ? 369 ASN A CG  1 
ATOM   2963  O OD1 . ASN A 1 369 ? -0.451  -25.867 -48.545 1.00 89.89  ? 369 ASN A OD1 1 
ATOM   2964  N ND2 . ASN A 1 369 ? -1.065  -25.613 -46.410 1.00 99.22  ? 369 ASN A ND2 1 
ATOM   2965  N N   . PRO A 1 370 ? 2.591   -26.200 -49.418 1.00 83.07  ? 370 PRO A N   1 
ATOM   2966  C CA  . PRO A 1 370 ? 3.511   -25.093 -49.701 1.00 87.72  ? 370 PRO A CA  1 
ATOM   2967  C C   . PRO A 1 370 ? 2.950   -23.685 -49.534 1.00 92.26  ? 370 PRO A C   1 
ATOM   2968  O O   . PRO A 1 370 ? 3.677   -22.710 -49.705 1.00 83.54  ? 370 PRO A O   1 
ATOM   2969  C CB  . PRO A 1 370 ? 3.796   -25.288 -51.193 1.00 94.19  ? 370 PRO A CB  1 
ATOM   2970  C CG  . PRO A 1 370 ? 2.474   -25.783 -51.727 1.00 84.84  ? 370 PRO A CG  1 
ATOM   2971  C CD  . PRO A 1 370 ? 1.949   -26.708 -50.644 1.00 76.42  ? 370 PRO A CD  1 
ATOM   2972  N N   . TRP A 1 371 ? 1.656   -23.596 -49.206 1.00 102.37 ? 371 TRP A N   1 
ATOM   2973  C CA  . TRP A 1 371 ? 0.942   -22.331 -49.191 1.00 97.03  ? 371 TRP A CA  1 
ATOM   2974  C C   . TRP A 1 371 ? 0.749   -21.849 -47.750 1.00 80.40  ? 371 TRP A C   1 
ATOM   2975  O O   . TRP A 1 371 ? 1.046   -22.594 -46.799 1.00 67.18  ? 371 TRP A O   1 
ATOM   2976  C CB  . TRP A 1 371 ? -0.383  -22.493 -49.944 1.00 98.37  ? 371 TRP A CB  1 
ATOM   2977  C CG  . TRP A 1 371 ? -0.240  -22.895 -51.381 1.00 102.85 ? 371 TRP A CG  1 
ATOM   2978  C CD1 . TRP A 1 371 ? -0.217  -24.167 -51.870 1.00 102.69 ? 371 TRP A CD1 1 
ATOM   2979  C CD2 . TRP A 1 371 ? -0.201  -22.030 -52.531 1.00 117.89 ? 371 TRP A CD2 1 
ATOM   2980  N NE1 . TRP A 1 371 ? -0.128  -24.155 -53.235 1.00 102.24 ? 371 TRP A NE1 1 
ATOM   2981  C CE2 . TRP A 1 371 ? -0.124  -22.860 -53.672 1.00 109.05 ? 371 TRP A CE2 1 
ATOM   2982  C CE3 . TRP A 1 371 ? -0.215  -20.641 -52.714 1.00 126.37 ? 371 TRP A CE3 1 
ATOM   2983  C CZ2 . TRP A 1 371 ? -0.058  -22.347 -54.967 1.00 113.37 ? 371 TRP A CZ2 1 
ATOM   2984  C CZ3 . TRP A 1 371 ? -0.149  -20.133 -53.995 1.00 120.40 ? 371 TRP A CZ3 1 
ATOM   2985  C CH2 . TRP A 1 371 ? -0.071  -20.978 -55.104 1.00 116.96 ? 371 TRP A CH2 1 
ATOM   2986  N N   . PRO A 1 372 ? 0.306   -20.572 -47.566 1.00 66.39  ? 372 PRO A N   1 
ATOM   2987  C CA  . PRO A 1 372 ? 0.075   -19.983 -46.234 1.00 71.88  ? 372 PRO A CA  1 
ATOM   2988  C C   . PRO A 1 372 ? -1.246  -20.348 -45.537 1.00 66.96  ? 372 PRO A C   1 
ATOM   2989  O O   . PRO A 1 372 ? -2.288  -20.492 -46.186 1.00 56.36  ? 372 PRO A O   1 
ATOM   2990  C CB  . PRO A 1 372 ? 0.094   -18.454 -46.472 1.00 67.99  ? 372 PRO A CB  1 
ATOM   2991  C CG  . PRO A 1 372 ? -0.174  -18.261 -47.961 1.00 66.44  ? 372 PRO A CG  1 
ATOM   2992  C CD  . PRO A 1 372 ? 0.037   -19.603 -48.639 1.00 65.23  ? 372 PRO A CD  1 
ATOM   2993  N N   . ASN A 1 373 ? -1.165  -20.527 -44.208 1.00 59.60  ? 373 ASN A N   1 
ATOM   2994  C CA  . ASN A 1 373 ? -2.326  -20.701 -43.351 1.00 60.37  ? 373 ASN A CA  1 
ATOM   2995  C C   . ASN A 1 373 ? -2.757  -19.332 -42.805 1.00 67.96  ? 373 ASN A C   1 
ATOM   2996  O O   . ASN A 1 373 ? -2.278  -18.298 -43.272 1.00 57.47  ? 373 ASN A O   1 
ATOM   2997  C CB  . ASN A 1 373 ? -2.046  -21.712 -42.236 1.00 61.26  ? 373 ASN A CB  1 
ATOM   2998  C CG  . ASN A 1 373 ? -0.951  -21.276 -41.289 1.00 61.74  ? 373 ASN A CG  1 
ATOM   2999  O OD1 . ASN A 1 373 ? -0.966  -20.156 -40.785 1.00 71.26  ? 373 ASN A OD1 1 
ATOM   3000  N ND2 . ASN A 1 373 ? 0.008   -22.155 -41.039 1.00 68.38  ? 373 ASN A ND2 1 
ATOM   3001  N N   . VAL A 1 374 ? -3.669  -19.336 -41.813 1.00 77.43  ? 374 VAL A N   1 
ATOM   3002  C CA  . VAL A 1 374 ? -4.334  -18.130 -41.319 1.00 68.60  ? 374 VAL A CA  1 
ATOM   3003  C C   . VAL A 1 374 ? -3.371  -17.290 -40.471 1.00 62.16  ? 374 VAL A C   1 
ATOM   3004  O O   . VAL A 1 374 ? -3.443  -16.061 -40.484 1.00 52.75  ? 374 VAL A O   1 
ATOM   3005  C CB  . VAL A 1 374 ? -5.618  -18.485 -40.540 1.00 72.98  ? 374 VAL A CB  1 
ATOM   3006  C CG1 . VAL A 1 374 ? -5.361  -19.392 -39.336 1.00 68.23  ? 374 VAL A CG1 1 
ATOM   3007  C CG2 . VAL A 1 374 ? -6.379  -17.237 -40.117 1.00 69.87  ? 374 VAL A CG2 1 
ATOM   3008  N N   . ASP A 1 375 ? -2.424  -17.963 -39.807 1.00 57.14  ? 375 ASP A N   1 
ATOM   3009  C CA  . ASP A 1 375 ? -1.503  -17.323 -38.890 1.00 57.11  ? 375 ASP A CA  1 
ATOM   3010  C C   . ASP A 1 375 ? -0.417  -16.532 -39.616 1.00 57.63  ? 375 ASP A C   1 
ATOM   3011  O O   . ASP A 1 375 ? 0.244   -15.682 -39.004 1.00 58.10  ? 375 ASP A O   1 
ATOM   3012  C CB  . ASP A 1 375 ? -0.931  -18.387 -37.968 1.00 64.95  ? 375 ASP A CB  1 
ATOM   3013  C CG  . ASP A 1 375 ? -2.059  -19.169 -37.324 1.00 77.67  ? 375 ASP A CG  1 
ATOM   3014  O OD1 . ASP A 1 375 ? -2.896  -18.509 -36.660 1.00 83.10  ? 375 ASP A OD1 1 
ATOM   3015  O OD2 . ASP A 1 375 ? -2.129  -20.407 -37.543 1.00 75.97  ? 375 ASP A OD2 1 
ATOM   3016  N N   . ALA A 1 376 ? -0.237  -16.774 -40.926 1.00 51.00  ? 376 ALA A N   1 
ATOM   3017  C CA  . ALA A 1 376 ? 0.633   -15.903 -41.700 1.00 49.77  ? 376 ALA A CA  1 
ATOM   3018  C C   . ALA A 1 376 ? 0.130   -14.455 -41.696 1.00 47.21  ? 376 ALA A C   1 
ATOM   3019  O O   . ALA A 1 376 ? 0.916   -13.563 -41.981 1.00 47.94  ? 376 ALA A O   1 
ATOM   3020  C CB  . ALA A 1 376 ? 0.802   -16.381 -43.121 1.00 45.93  ? 376 ALA A CB  1 
ATOM   3021  N N   . HIS A 1 377 ? -1.170  -14.204 -41.448 1.00 46.85  ? 377 HIS A N   1 
ATOM   3022  C CA  . HIS A 1 377 ? -1.705  -12.883 -41.734 1.00 47.08  ? 377 HIS A CA  1 
ATOM   3023  C C   . HIS A 1 377 ? -2.207  -12.115 -40.499 1.00 50.37  ? 377 HIS A C   1 
ATOM   3024  O O   . HIS A 1 377 ? -2.291  -10.865 -40.552 1.00 43.89  ? 377 HIS A O   1 
ATOM   3025  C CB  . HIS A 1 377 ? -2.765  -12.975 -42.825 1.00 44.55  ? 377 HIS A CB  1 
ATOM   3026  C CG  . HIS A 1 377 ? -2.652  -11.855 -43.784 1.00 52.72  ? 377 HIS A CG  1 
ATOM   3027  N ND1 . HIS A 1 377 ? -2.563  -10.537 -43.400 1.00 57.07  ? 377 HIS A ND1 1 
ATOM   3028  C CD2 . HIS A 1 377 ? -2.549  -11.867 -45.119 1.00 53.34  ? 377 HIS A CD2 1 
ATOM   3029  C CE1 . HIS A 1 377 ? -2.465  -9.784  -44.486 1.00 59.02  ? 377 HIS A CE1 1 
ATOM   3030  N NE2 . HIS A 1 377 ? -2.432  -10.580 -45.541 1.00 52.49  ? 377 HIS A NE2 1 
ATOM   3031  N N   . SER A 1 378 ? -2.545  -12.821 -39.407 1.00 41.91  ? 378 SER A N   1 
ATOM   3032  C CA  . SER A 1 378 ? -3.361  -12.199 -38.362 1.00 47.44  ? 378 SER A CA  1 
ATOM   3033  C C   . SER A 1 378 ? -2.551  -11.182 -37.553 1.00 46.08  ? 378 SER A C   1 
ATOM   3034  O O   . SER A 1 378 ? -3.053  -10.101 -37.259 1.00 47.54  ? 378 SER A O   1 
ATOM   3035  C CB  . SER A 1 378 ? -4.020  -13.207 -37.491 1.00 43.50  ? 378 SER A CB  1 
ATOM   3036  O OG  . SER A 1 378 ? -3.056  -14.113 -37.000 1.00 52.88  ? 378 SER A OG  1 
ATOM   3037  N N   . GLY A 1 379 ? -1.279  -11.488 -37.266 1.00 48.01  ? 379 GLY A N   1 
ATOM   3038  C CA  . GLY A 1 379 ? -0.434  -10.649 -36.422 1.00 40.99  ? 379 GLY A CA  1 
ATOM   3039  C C   . GLY A 1 379 ? -0.252  -9.221  -36.952 1.00 45.53  ? 379 GLY A C   1 
ATOM   3040  O O   . GLY A 1 379 ? -0.325  -8.242  -36.201 1.00 47.42  ? 379 GLY A O   1 
ATOM   3041  N N   . VAL A 1 380 ? -0.001  -9.080  -38.254 1.00 41.95  ? 380 VAL A N   1 
ATOM   3042  C CA  . VAL A 1 380 ? 0.369   -7.776  -38.766 1.00 46.46  ? 380 VAL A CA  1 
ATOM   3043  C C   . VAL A 1 380 ? -0.817  -6.843  -38.644 1.00 39.93  ? 380 VAL A C   1 
ATOM   3044  O O   . VAL A 1 380 ? -0.614  -5.650  -38.442 1.00 44.37  ? 380 VAL A O   1 
ATOM   3045  C CB  . VAL A 1 380 ? 0.923   -7.788  -40.206 1.00 53.38  ? 380 VAL A CB  1 
ATOM   3046  C CG1 . VAL A 1 380 ? 2.298   -8.421  -40.224 1.00 59.56  ? 380 VAL A CG1 1 
ATOM   3047  C CG2 . VAL A 1 380 ? 0.004   -8.463  -41.206 1.00 57.18  ? 380 VAL A CG2 1 
ATOM   3048  N N   . LEU A 1 381 ? -2.020  -7.408  -38.774 1.00 37.99  ? 381 LEU A N   1 
ATOM   3049  C CA  . LEU A 1 381 ? -3.263  -6.674  -38.640 1.00 37.14  ? 381 LEU A CA  1 
ATOM   3050  C C   . LEU A 1 381 ? -3.416  -6.148  -37.214 1.00 44.03  ? 381 LEU A C   1 
ATOM   3051  O O   . LEU A 1 381 ? -3.580  -4.943  -37.026 1.00 49.71  ? 381 LEU A O   1 
ATOM   3052  C CB  . LEU A 1 381 ? -4.405  -7.615  -39.023 1.00 45.04  ? 381 LEU A CB  1 
ATOM   3053  C CG  . LEU A 1 381 ? -4.403  -8.132  -40.466 1.00 47.30  ? 381 LEU A CG  1 
ATOM   3054  C CD1 . LEU A 1 381 ? -5.644  -8.955  -40.753 1.00 48.56  ? 381 LEU A CD1 1 
ATOM   3055  C CD2 . LEU A 1 381 ? -4.320  -7.001  -41.471 1.00 49.52  ? 381 LEU A CD2 1 
ATOM   3056  N N   . LEU A 1 382 ? -3.349  -7.051  -36.224 1.00 43.08  ? 382 LEU A N   1 
ATOM   3057  C CA  . LEU A 1 382 ? -3.435  -6.681  -34.819 1.00 40.59  ? 382 LEU A CA  1 
ATOM   3058  C C   . LEU A 1 382 ? -2.400  -5.613  -34.489 1.00 39.36  ? 382 LEU A C   1 
ATOM   3059  O O   . LEU A 1 382 ? -2.720  -4.613  -33.858 1.00 40.17  ? 382 LEU A O   1 
ATOM   3060  C CB  . LEU A 1 382 ? -3.234  -7.925  -33.948 1.00 35.79  ? 382 LEU A CB  1 
ATOM   3061  C CG  . LEU A 1 382 ? -4.373  -8.937  -34.063 1.00 40.14  ? 382 LEU A CG  1 
ATOM   3062  C CD1 . LEU A 1 382 ? -4.081  -10.251 -33.331 1.00 41.78  ? 382 LEU A CD1 1 
ATOM   3063  C CD2 . LEU A 1 382 ? -5.679  -8.334  -33.573 1.00 38.90  ? 382 LEU A CD2 1 
ATOM   3064  N N   . TRP A 1 383 ? -1.154  -5.850  -34.912 1.00 41.87  ? 383 TRP A N   1 
ATOM   3065  C CA  . TRP A 1 383 ? -0.060  -4.970  -34.575 1.00 43.03  ? 383 TRP A CA  1 
ATOM   3066  C C   . TRP A 1 383 ? -0.308  -3.572  -35.154 1.00 41.84  ? 383 TRP A C   1 
ATOM   3067  O O   . TRP A 1 383 ? -0.131  -2.563  -34.482 1.00 40.33  ? 383 TRP A O   1 
ATOM   3068  C CB  . TRP A 1 383 ? 1.268   -5.594  -35.030 1.00 44.46  ? 383 TRP A CB  1 
ATOM   3069  C CG  . TRP A 1 383 ? 2.468   -4.785  -34.650 1.00 42.99  ? 383 TRP A CG  1 
ATOM   3070  C CD1 . TRP A 1 383 ? 2.945   -3.681  -35.303 1.00 40.19  ? 383 TRP A CD1 1 
ATOM   3071  C CD2 . TRP A 1 383 ? 3.300   -4.961  -33.493 1.00 39.84  ? 383 TRP A CD2 1 
ATOM   3072  N NE1 . TRP A 1 383 ? 4.042   -3.188  -34.653 1.00 36.79  ? 383 TRP A NE1 1 
ATOM   3073  C CE2 . TRP A 1 383 ? 4.276   -3.935  -33.531 1.00 36.93  ? 383 TRP A CE2 1 
ATOM   3074  C CE3 . TRP A 1 383 ? 3.324   -5.871  -32.429 1.00 41.92  ? 383 TRP A CE3 1 
ATOM   3075  C CZ2 . TRP A 1 383 ? 5.270   -3.808  -32.554 1.00 41.19  ? 383 TRP A CZ2 1 
ATOM   3076  C CZ3 . TRP A 1 383 ? 4.296   -5.741  -31.454 1.00 37.25  ? 383 TRP A CZ3 1 
ATOM   3077  C CH2 . TRP A 1 383 ? 5.251   -4.718  -31.512 1.00 40.15  ? 383 TRP A CH2 1 
ATOM   3078  N N   . HIS A 1 384 ? -0.813  -3.525  -36.377 1.00 42.47  ? 384 HIS A N   1 
ATOM   3079  C CA  . HIS A 1 384 ? -1.048  -2.274  -37.067 1.00 46.42  ? 384 HIS A CA  1 
ATOM   3080  C C   . HIS A 1 384 ? -2.003  -1.357  -36.287 1.00 45.46  ? 384 HIS A C   1 
ATOM   3081  O O   . HIS A 1 384 ? -1.780  -0.159  -36.263 1.00 47.91  ? 384 HIS A O   1 
ATOM   3082  C CB  . HIS A 1 384 ? -1.541  -2.575  -38.482 1.00 45.43  ? 384 HIS A CB  1 
ATOM   3083  C CG  . HIS A 1 384 ? -1.971  -1.345  -39.179 1.00 47.91  ? 384 HIS A CG  1 
ATOM   3084  N ND1 . HIS A 1 384 ? -1.102  -0.518  -39.849 1.00 53.76  ? 384 HIS A ND1 1 
ATOM   3085  C CD2 . HIS A 1 384 ? -3.182  -0.777  -39.264 1.00 52.17  ? 384 HIS A CD2 1 
ATOM   3086  C CE1 . HIS A 1 384 ? -1.781  0.506   -40.345 1.00 55.23  ? 384 HIS A CE1 1 
ATOM   3087  N NE2 . HIS A 1 384 ? -3.043  0.385   -39.976 1.00 50.54  ? 384 HIS A NE2 1 
ATOM   3088  N N   . TYR A 1 385 ? -3.039  -1.899  -35.632 1.00 47.70  ? 385 TYR A N   1 
ATOM   3089  C CA  . TYR A 1 385 ? -4.012  -1.106  -34.894 1.00 46.46  ? 385 TYR A CA  1 
ATOM   3090  C C   . TYR A 1 385 ? -3.617  -0.963  -33.428 1.00 47.48  ? 385 TYR A C   1 
ATOM   3091  O O   . TYR A 1 385 ? -4.382  -0.429  -32.647 1.00 45.43  ? 385 TYR A O   1 
ATOM   3092  C CB  . TYR A 1 385 ? -5.421  -1.697  -35.043 1.00 46.96  ? 385 TYR A CB  1 
ATOM   3093  C CG  . TYR A 1 385 ? -5.941  -1.568  -36.444 1.00 46.09  ? 385 TYR A CG  1 
ATOM   3094  C CD1 . TYR A 1 385 ? -6.345  -0.341  -36.954 1.00 51.79  ? 385 TYR A CD1 1 
ATOM   3095  C CD2 . TYR A 1 385 ? -5.925  -2.650  -37.307 1.00 50.62  ? 385 TYR A CD2 1 
ATOM   3096  C CE1 . TYR A 1 385 ? -6.787  -0.214  -38.271 1.00 48.32  ? 385 TYR A CE1 1 
ATOM   3097  C CE2 . TYR A 1 385 ? -6.332  -2.535  -38.631 1.00 50.62  ? 385 TYR A CE2 1 
ATOM   3098  C CZ  . TYR A 1 385 ? -6.764  -1.314  -39.114 1.00 48.82  ? 385 TYR A CZ  1 
ATOM   3099  O OH  . TYR A 1 385 ? -7.149  -1.235  -40.420 1.00 49.73  ? 385 TYR A OH  1 
ATOM   3100  N N   . GLY A 1 386 ? -2.417  -1.409  -33.043 1.00 53.63  ? 386 GLY A N   1 
ATOM   3101  C CA  . GLY A 1 386 ? -1.916  -1.154  -31.697 1.00 49.30  ? 386 GLY A CA  1 
ATOM   3102  C C   . GLY A 1 386 ? -2.192  -2.277  -30.684 1.00 49.39  ? 386 GLY A C   1 
ATOM   3103  O O   . GLY A 1 386 ? -2.003  -2.067  -29.490 1.00 41.44  ? 386 GLY A O   1 
ATOM   3104  N N   . ILE A 1 387 ? -2.592  -3.483  -31.130 1.00 44.12  ? 387 ILE A N   1 
ATOM   3105  C CA  . ILE A 1 387 ? -2.627  -4.612  -30.207 1.00 43.59  ? 387 ILE A CA  1 
ATOM   3106  C C   . ILE A 1 387 ? -1.289  -5.328  -30.344 1.00 38.19  ? 387 ILE A C   1 
ATOM   3107  O O   . ILE A 1 387 ? -1.108  -6.076  -31.290 1.00 42.54  ? 387 ILE A O   1 
ATOM   3108  C CB  . ILE A 1 387 ? -3.820  -5.558  -30.458 1.00 39.64  ? 387 ILE A CB  1 
ATOM   3109  C CG1 . ILE A 1 387 ? -5.141  -4.802  -30.538 1.00 46.13  ? 387 ILE A CG1 1 
ATOM   3110  C CG2 . ILE A 1 387 ? -3.889  -6.643  -29.396 1.00 40.80  ? 387 ILE A CG2 1 
ATOM   3111  C CD1 . ILE A 1 387 ? -5.523  -4.389  -31.945 1.00 51.88  ? 387 ILE A CD1 1 
ATOM   3112  N N   . ARG A 1 388 ? -0.360  -5.047  -29.428 1.00 38.65  ? 388 ARG A N   1 
ATOM   3113  C CA  . ARG A 1 388 ? 1.057   -5.384  -29.547 1.00 43.69  ? 388 ARG A CA  1 
ATOM   3114  C C   . ARG A 1 388 ? 1.483   -6.405  -28.491 1.00 44.18  ? 388 ARG A C   1 
ATOM   3115  O O   . ARG A 1 388 ? 2.664   -6.675  -28.303 1.00 45.68  ? 388 ARG A O   1 
ATOM   3116  C CB  . ARG A 1 388 ? 1.922   -4.136  -29.326 1.00 47.43  ? 388 ARG A CB  1 
ATOM   3117  C CG  . ARG A 1 388 ? 1.505   -2.960  -30.196 1.00 60.11  ? 388 ARG A CG  1 
ATOM   3118  C CD  . ARG A 1 388 ? 2.582   -2.013  -30.710 1.00 62.29  ? 388 ARG A CD  1 
ATOM   3119  N NE  . ARG A 1 388 ? 2.057   -1.529  -31.998 1.00 72.41  ? 388 ARG A NE  1 
ATOM   3120  C CZ  . ARG A 1 388 ? 2.642   -0.647  -32.802 1.00 59.87  ? 388 ARG A CZ  1 
ATOM   3121  N NH1 . ARG A 1 388 ? 3.850   -0.194  -32.515 1.00 54.56  ? 388 ARG A NH1 1 
ATOM   3122  N NH2 . ARG A 1 388 ? 2.004   -0.233  -33.887 1.00 56.01  ? 388 ARG A NH2 1 
ATOM   3123  N N   . GLU A 1 389 ? 0.520   -6.899  -27.735 1.00 44.54  ? 389 GLU A N   1 
ATOM   3124  C CA  . GLU A 1 389 ? 0.796   -7.750  -26.593 1.00 41.04  ? 389 GLU A CA  1 
ATOM   3125  C C   . GLU A 1 389 ? 0.736   -9.192  -27.069 1.00 36.51  ? 389 GLU A C   1 
ATOM   3126  O O   . GLU A 1 389 ? -0.336  -9.783  -27.078 1.00 39.76  ? 389 GLU A O   1 
ATOM   3127  C CB  . GLU A 1 389 ? -0.240  -7.462  -25.507 1.00 39.25  ? 389 GLU A CB  1 
ATOM   3128  C CG  . GLU A 1 389 ? -0.081  -6.089  -24.897 1.00 45.91  ? 389 GLU A CG  1 
ATOM   3129  C CD  . GLU A 1 389 ? -0.732  -4.925  -25.631 1.00 49.37  ? 389 GLU A CD  1 
ATOM   3130  O OE1 . GLU A 1 389 ? -0.443  -3.768  -25.234 1.00 46.25  ? 389 GLU A OE1 1 
ATOM   3131  O OE2 . GLU A 1 389 ? -1.573  -5.170  -26.538 1.00 42.01  ? 389 GLU A OE2 1 
ATOM   3132  N N   . TYR A 1 390 ? 1.866   -9.680  -27.575 1.00 36.87  ? 390 TYR A N   1 
ATOM   3133  C CA  . TYR A 1 390 ? 1.969   -10.980 -28.225 1.00 39.89  ? 390 TYR A CA  1 
ATOM   3134  C C   . TYR A 1 390 ? 1.179   -12.052 -27.476 1.00 37.49  ? 390 TYR A C   1 
ATOM   3135  O O   . TYR A 1 390 ? 0.399   -12.778 -28.082 1.00 36.97  ? 390 TYR A O   1 
ATOM   3136  C CB  . TYR A 1 390 ? 3.437   -11.417 -28.314 1.00 43.09  ? 390 TYR A CB  1 
ATOM   3137  C CG  . TYR A 1 390 ? 4.338   -10.532 -29.143 1.00 47.91  ? 390 TYR A CG  1 
ATOM   3138  C CD1 . TYR A 1 390 ? 4.349   -10.639 -30.528 1.00 48.33  ? 390 TYR A CD1 1 
ATOM   3139  C CD2 . TYR A 1 390 ? 5.188   -9.597  -28.551 1.00 47.60  ? 390 TYR A CD2 1 
ATOM   3140  C CE1 . TYR A 1 390 ? 5.149   -9.829  -31.308 1.00 47.72  ? 390 TYR A CE1 1 
ATOM   3141  C CE2 . TYR A 1 390 ? 6.005   -8.777  -29.317 1.00 46.19  ? 390 TYR A CE2 1 
ATOM   3142  C CZ  . TYR A 1 390 ? 5.992   -8.910  -30.701 1.00 51.55  ? 390 TYR A CZ  1 
ATOM   3143  O OH  . TYR A 1 390 ? 6.766   -8.126  -31.512 1.00 48.64  ? 390 TYR A OH  1 
ATOM   3144  N N   . ASP A 1 391 ? 1.376   -12.180 -26.162 1.00 38.96  ? 391 ASP A N   1 
ATOM   3145  C CA  . ASP A 1 391 ? 0.873   -13.361 -25.450 1.00 41.12  ? 391 ASP A CA  1 
ATOM   3146  C C   . ASP A 1 391 ? -0.650  -13.397 -25.453 1.00 37.06  ? 391 ASP A C   1 
ATOM   3147  O O   . ASP A 1 391 ? -1.240  -14.478 -25.407 1.00 40.01  ? 391 ASP A O   1 
ATOM   3148  C CB  . ASP A 1 391 ? 1.406   -13.438 -24.016 1.00 45.68  ? 391 ASP A CB  1 
ATOM   3149  C CG  . ASP A 1 391 ? 2.905   -13.733 -23.914 1.00 51.74  ? 391 ASP A CG  1 
ATOM   3150  O OD1 . ASP A 1 391 ? 3.475   -14.299 -24.878 1.00 56.89  ? 391 ASP A OD1 1 
ATOM   3151  O OD2 . ASP A 1 391 ? 3.510   -13.364 -22.874 1.00 58.23  ? 391 ASP A OD2 1 
ATOM   3152  N N   . PHE A 1 392 ? -1.253  -12.211 -25.601 1.00 35.64  ? 392 PHE A N   1 
ATOM   3153  C CA  . PHE A 1 392 ? -2.694  -12.022 -25.538 1.00 37.08  ? 392 PHE A CA  1 
ATOM   3154  C C   . PHE A 1 392 ? -3.382  -12.460 -26.834 1.00 33.90  ? 392 PHE A C   1 
ATOM   3155  O O   . PHE A 1 392 ? -4.595  -12.679 -26.848 1.00 34.52  ? 392 PHE A O   1 
ATOM   3156  C CB  . PHE A 1 392 ? -3.039  -10.551 -25.286 1.00 39.48  ? 392 PHE A CB  1 
ATOM   3157  C CG  . PHE A 1 392 ? -4.486  -10.362 -24.913 1.00 36.19  ? 392 PHE A CG  1 
ATOM   3158  C CD1 . PHE A 1 392 ? -4.936  -10.698 -23.648 1.00 32.04  ? 392 PHE A CD1 1 
ATOM   3159  C CD2 . PHE A 1 392 ? -5.401  -9.885  -25.836 1.00 35.32  ? 392 PHE A CD2 1 
ATOM   3160  C CE1 . PHE A 1 392 ? -6.275  -10.589 -23.322 1.00 31.26  ? 392 PHE A CE1 1 
ATOM   3161  C CE2 . PHE A 1 392 ? -6.735  -9.750  -25.492 1.00 33.92  ? 392 PHE A CE2 1 
ATOM   3162  C CZ  . PHE A 1 392 ? -7.165  -10.115 -24.241 1.00 32.61  ? 392 PHE A CZ  1 
ATOM   3163  N N   . TYR A 1 393 ? -2.612  -12.563 -27.915 1.00 30.42  ? 393 TYR A N   1 
ATOM   3164  C CA  . TYR A 1 393 ? -3.132  -12.986 -29.200 1.00 35.82  ? 393 TYR A CA  1 
ATOM   3165  C C   . TYR A 1 393 ? -3.867  -14.313 -29.065 1.00 33.65  ? 393 TYR A C   1 
ATOM   3166  O O   . TYR A 1 393 ? -4.888  -14.484 -29.715 1.00 39.09  ? 393 TYR A O   1 
ATOM   3167  C CB  . TYR A 1 393 ? -2.019  -13.077 -30.268 1.00 38.17  ? 393 TYR A CB  1 
ATOM   3168  C CG  . TYR A 1 393 ? -1.459  -11.753 -30.734 1.00 39.97  ? 393 TYR A CG  1 
ATOM   3169  C CD1 . TYR A 1 393 ? -1.795  -10.544 -30.135 1.00 38.46  ? 393 TYR A CD1 1 
ATOM   3170  C CD2 . TYR A 1 393 ? -0.528  -11.717 -31.759 1.00 40.68  ? 393 TYR A CD2 1 
ATOM   3171  C CE1 . TYR A 1 393 ? -1.273  -9.336  -30.586 1.00 37.31  ? 393 TYR A CE1 1 
ATOM   3172  C CE2 . TYR A 1 393 ? -0.013  -10.521 -32.227 1.00 39.11  ? 393 TYR A CE2 1 
ATOM   3173  C CZ  . TYR A 1 393 ? -0.352  -9.325  -31.625 1.00 41.91  ? 393 TYR A CZ  1 
ATOM   3174  O OH  . TYR A 1 393 ? 0.253   -8.165  -32.120 1.00 40.84  ? 393 TYR A OH  1 
ATOM   3175  N N   . THR A 1 394 ? -3.360  -15.252 -28.248 1.00 33.29  ? 394 THR A N   1 
ATOM   3176  C CA  . THR A 1 394 ? -4.021  -16.544 -28.093 1.00 33.23  ? 394 THR A CA  1 
ATOM   3177  C C   . THR A 1 394 ? -5.377  -16.376 -27.403 1.00 36.13  ? 394 THR A C   1 
ATOM   3178  O O   . THR A 1 394 ? -6.316  -17.124 -27.645 1.00 34.29  ? 394 THR A O   1 
ATOM   3179  C CB  . THR A 1 394 ? -3.087  -17.512 -27.362 1.00 37.63  ? 394 THR A CB  1 
ATOM   3180  O OG1 . THR A 1 394 ? -1.794  -17.333 -27.949 1.00 38.79  ? 394 THR A OG1 1 
ATOM   3181  C CG2 . THR A 1 394 ? -3.521  -18.956 -27.461 1.00 40.29  ? 394 THR A CG2 1 
ATOM   3182  N N   . VAL A 1 395 ? -5.526  -15.371 -26.540 1.00 32.87  ? 395 VAL A N   1 
ATOM   3183  C CA  . VAL A 1 395 ? -6.818  -15.184 -25.894 1.00 32.90  ? 395 VAL A CA  1 
ATOM   3184  C C   . VAL A 1 395 ? -7.859  -14.781 -26.945 1.00 32.00  ? 395 VAL A C   1 
ATOM   3185  O O   . VAL A 1 395 ? -8.989  -15.233 -26.870 1.00 31.23  ? 395 VAL A O   1 
ATOM   3186  C CB  . VAL A 1 395 ? -6.757  -14.117 -24.778 1.00 33.97  ? 395 VAL A CB  1 
ATOM   3187  C CG1 . VAL A 1 395 ? -8.135  -13.878 -24.193 1.00 33.36  ? 395 VAL A CG1 1 
ATOM   3188  C CG2 . VAL A 1 395 ? -5.743  -14.471 -23.707 1.00 34.11  ? 395 VAL A CG2 1 
ATOM   3189  N N   . LEU A 1 396 ? -7.493  -13.870 -27.866 1.00 32.41  ? 396 LEU A N   1 
ATOM   3190  C CA  . LEU A 1 396 ? -8.344  -13.457 -28.968 1.00 36.16  ? 396 LEU A CA  1 
ATOM   3191  C C   . LEU A 1 396 ? -8.766  -14.671 -29.786 1.00 37.06  ? 396 LEU A C   1 
ATOM   3192  O O   . LEU A 1 396 ? -9.952  -14.869 -30.072 1.00 36.65  ? 396 LEU A O   1 
ATOM   3193  C CB  . LEU A 1 396 ? -7.620  -12.460 -29.882 1.00 36.37  ? 396 LEU A CB  1 
ATOM   3194  C CG  . LEU A 1 396 ? -7.284  -11.108 -29.261 1.00 36.47  ? 396 LEU A CG  1 
ATOM   3195  C CD1 . LEU A 1 396 ? -6.641  -10.180 -30.280 1.00 42.62  ? 396 LEU A CD1 1 
ATOM   3196  C CD2 . LEU A 1 396 ? -8.531  -10.472 -28.717 1.00 34.52  ? 396 LEU A CD2 1 
ATOM   3197  N N   . PHE A 1 397 ? -7.788  -15.496 -30.127 1.00 37.22  ? 397 PHE A N   1 
ATOM   3198  C CA  . PHE A 1 397 ? -8.061  -16.762 -30.800 1.00 40.36  ? 397 PHE A CA  1 
ATOM   3199  C C   . PHE A 1 397 ? -9.129  -17.526 -30.014 1.00 39.07  ? 397 PHE A C   1 
ATOM   3200  O O   . PHE A 1 397 ? -10.119 -18.024 -30.565 1.00 39.62  ? 397 PHE A O   1 
ATOM   3201  C CB  . PHE A 1 397 ? -6.726  -17.492 -31.009 1.00 43.57  ? 397 PHE A CB  1 
ATOM   3202  C CG  . PHE A 1 397 ? -6.733  -18.720 -31.887 1.00 52.53  ? 397 PHE A CG  1 
ATOM   3203  C CD1 . PHE A 1 397 ? -7.911  -19.283 -32.367 1.00 54.37  ? 397 PHE A CD1 1 
ATOM   3204  C CD2 . PHE A 1 397 ? -5.529  -19.319 -32.241 1.00 59.89  ? 397 PHE A CD2 1 
ATOM   3205  C CE1 . PHE A 1 397 ? -7.883  -20.410 -33.180 1.00 57.29  ? 397 PHE A CE1 1 
ATOM   3206  C CE2 . PHE A 1 397 ? -5.503  -20.442 -33.058 1.00 62.35  ? 397 PHE A CE2 1 
ATOM   3207  C CZ  . PHE A 1 397 ? -6.685  -20.986 -33.525 1.00 57.51  ? 397 PHE A CZ  1 
ATOM   3208  N N   . GLY A 1 398 ? -8.953  -17.589 -28.697 1.00 42.19  ? 398 GLY A N   1 
ATOM   3209  C CA  . GLY A 1 398 ? -9.813  -18.396 -27.853 1.00 34.92  ? 398 GLY A CA  1 
ATOM   3210  C C   . GLY A 1 398 ? -11.240 -17.866 -27.807 1.00 35.36  ? 398 GLY A C   1 
ATOM   3211  O O   . GLY A 1 398 ? -12.200 -18.623 -27.802 1.00 37.23  ? 398 GLY A O   1 
ATOM   3212  N N   . VAL A 1 399 ? -11.391 -16.553 -27.696 1.00 39.82  ? 399 VAL A N   1 
ATOM   3213  C CA  . VAL A 1 399 ? -12.721 -15.963 -27.677 1.00 36.18  ? 399 VAL A CA  1 
ATOM   3214  C C   . VAL A 1 399 ? -13.474 -16.399 -28.936 1.00 33.63  ? 399 VAL A C   1 
ATOM   3215  O O   . VAL A 1 399 ? -14.651 -16.698 -28.896 1.00 35.55  ? 399 VAL A O   1 
ATOM   3216  C CB  . VAL A 1 399 ? -12.625 -14.427 -27.616 1.00 38.79  ? 399 VAL A CB  1 
ATOM   3217  C CG1 . VAL A 1 399 ? -13.976 -13.755 -27.858 1.00 39.22  ? 399 VAL A CG1 1 
ATOM   3218  C CG2 . VAL A 1 399 ? -12.027 -13.951 -26.296 1.00 38.98  ? 399 VAL A CG2 1 
ATOM   3219  N N   . SER A 1 400 ? -12.785 -16.392 -30.069 1.00 36.36  ? 400 SER A N   1 
ATOM   3220  C CA  . SER A 1 400 ? -13.373 -16.717 -31.353 1.00 39.78  ? 400 SER A CA  1 
ATOM   3221  C C   . SER A 1 400 ? -13.700 -18.209 -31.437 1.00 38.29  ? 400 SER A C   1 
ATOM   3222  O O   . SER A 1 400 ? -14.818 -18.597 -31.745 1.00 37.33  ? 400 SER A O   1 
ATOM   3223  C CB  . SER A 1 400 ? -12.416 -16.293 -32.438 1.00 44.16  ? 400 SER A CB  1 
ATOM   3224  O OG  . SER A 1 400 ? -12.754 -16.870 -33.687 1.00 39.90  ? 400 SER A OG  1 
ATOM   3225  N N   . ARG A 1 401 ? -12.739 -19.058 -31.080 1.00 39.53  ? 401 ARG A N   1 
ATOM   3226  C CA  . ARG A 1 401 ? -12.944 -20.503 -31.112 1.00 40.69  ? 401 ARG A CA  1 
ATOM   3227  C C   . ARG A 1 401 ? -14.127 -20.968 -30.259 1.00 37.86  ? 401 ARG A C   1 
ATOM   3228  O O   . ARG A 1 401 ? -14.690 -22.024 -30.496 1.00 39.41  ? 401 ARG A O   1 
ATOM   3229  C CB  . ARG A 1 401 ? -11.643 -21.192 -30.713 1.00 39.99  ? 401 ARG A CB  1 
ATOM   3230  C CG  . ARG A 1 401 ? -11.584 -22.657 -31.071 1.00 41.03  ? 401 ARG A CG  1 
ATOM   3231  C CD  . ARG A 1 401 ? -12.219 -23.032 -32.397 1.00 43.70  ? 401 ARG A CD  1 
ATOM   3232  N NE  . ARG A 1 401 ? -11.550 -22.479 -33.564 1.00 47.83  ? 401 ARG A NE  1 
ATOM   3233  C CZ  . ARG A 1 401 ? -10.459 -22.967 -34.158 1.00 45.76  ? 401 ARG A CZ  1 
ATOM   3234  N NH1 . ARG A 1 401 ? -9.752  -23.930 -33.588 1.00 46.17  ? 401 ARG A NH1 1 
ATOM   3235  N NH2 . ARG A 1 401 ? -10.052 -22.436 -35.305 1.00 39.68  ? 401 ARG A NH2 1 
ATOM   3236  N N   . ALA A 1 402 ? -14.511 -20.188 -29.258 1.00 41.15  ? 402 ALA A N   1 
ATOM   3237  C CA  . ALA A 1 402 ? -15.653 -20.502 -28.411 1.00 36.49  ? 402 ALA A CA  1 
ATOM   3238  C C   . ALA A 1 402 ? -16.943 -20.637 -29.229 1.00 38.25  ? 402 ALA A C   1 
ATOM   3239  O O   . ALA A 1 402 ? -17.871 -21.376 -28.864 1.00 37.15  ? 402 ALA A O   1 
ATOM   3240  C CB  . ALA A 1 402 ? -15.763 -19.383 -27.382 1.00 36.90  ? 402 ALA A CB  1 
ATOM   3241  N N   . LEU A 1 403 ? -17.032 -19.872 -30.324 1.00 37.41  ? 403 LEU A N   1 
ATOM   3242  C CA  . LEU A 1 403 ? -18.179 -19.943 -31.221 1.00 35.30  ? 403 LEU A CA  1 
ATOM   3243  C C   . LEU A 1 403 ? -18.388 -21.374 -31.727 1.00 31.43  ? 403 LEU A C   1 
ATOM   3244  O O   . LEU A 1 403 ? -19.466 -21.957 -31.560 1.00 38.66  ? 403 LEU A O   1 
ATOM   3245  C CB  . LEU A 1 403 ? -17.986 -18.957 -32.377 1.00 35.14  ? 403 LEU A CB  1 
ATOM   3246  C CG  . LEU A 1 403 ? -18.045 -17.492 -31.975 1.00 37.32  ? 403 LEU A CG  1 
ATOM   3247  C CD1 . LEU A 1 403 ? -17.563 -16.591 -33.102 1.00 38.93  ? 403 LEU A CD1 1 
ATOM   3248  C CD2 . LEU A 1 403 ? -19.437 -17.078 -31.504 1.00 38.58  ? 403 LEU A CD2 1 
ATOM   3249  N N   . GLY A 1 404 ? -17.358 -21.967 -32.298 1.00 33.54  ? 404 GLY A N   1 
ATOM   3250  C CA  . GLY A 1 404 ? -17.437 -23.348 -32.759 1.00 36.66  ? 404 GLY A CA  1 
ATOM   3251  C C   . GLY A 1 404 ? -17.584 -24.363 -31.628 1.00 40.71  ? 404 GLY A C   1 
ATOM   3252  O O   . GLY A 1 404 ? -18.307 -25.348 -31.750 1.00 42.37  ? 404 GLY A O   1 
ATOM   3253  N N   . CYS A 1 405 ? -16.835 -24.160 -30.536 1.00 43.67  ? 405 CYS A N   1 
ATOM   3254  C CA  . CYS A 1 405 ? -16.852 -25.122 -29.442 1.00 41.47  ? 405 CYS A CA  1 
ATOM   3255  C C   . CYS A 1 405 ? -18.229 -25.192 -28.798 1.00 34.16  ? 405 CYS A C   1 
ATOM   3256  O O   . CYS A 1 405 ? -18.678 -26.259 -28.423 1.00 38.51  ? 405 CYS A O   1 
ATOM   3257  C CB  . CYS A 1 405 ? -15.817 -24.796 -28.362 1.00 45.93  ? 405 CYS A CB  1 
ATOM   3258  S SG  . CYS A 1 405 ? -14.111 -25.101 -28.898 1.00 48.12  ? 405 CYS A SG  1 
ATOM   3259  N N   . THR A 1 406 ? -18.892 -24.055 -28.635 1.00 36.78  ? 406 THR A N   1 
ATOM   3260  C CA  . THR A 1 406 ? -20.226 -24.071 -28.036 1.00 41.94  ? 406 THR A CA  1 
ATOM   3261  C C   . THR A 1 406 ? -21.196 -24.713 -29.024 1.00 38.70  ? 406 THR A C   1 
ATOM   3262  O O   . THR A 1 406 ? -21.963 -25.575 -28.634 1.00 39.67  ? 406 THR A O   1 
ATOM   3263  C CB  . THR A 1 406 ? -20.672 -22.665 -27.608 1.00 40.10  ? 406 THR A CB  1 
ATOM   3264  O OG1 . THR A 1 406 ? -20.613 -21.763 -28.725 1.00 39.58  ? 406 THR A OG1 1 
ATOM   3265  C CG2 . THR A 1 406 ? -19.780 -22.112 -26.520 1.00 39.23  ? 406 THR A CG2 1 
ATOM   3266  N N   . ALA A 1 407 ? -21.108 -24.342 -30.313 1.00 46.60  ? 407 ALA A N   1 
ATOM   3267  C CA  . ALA A 1 407 ? -21.952 -24.946 -31.352 1.00 39.74  ? 407 ALA A CA  1 
ATOM   3268  C C   . ALA A 1 407 ? -21.765 -26.457 -31.341 1.00 39.42  ? 407 ALA A C   1 
ATOM   3269  O O   . ALA A 1 407 ? -22.709 -27.191 -31.097 1.00 40.90  ? 407 ALA A O   1 
ATOM   3270  C CB  . ALA A 1 407 ? -21.608 -24.409 -32.689 1.00 39.68  ? 407 ALA A CB  1 
ATOM   3271  N N   . GLN A 1 408 ? -20.528 -26.920 -31.463 1.00 39.96  ? 408 GLN A N   1 
ATOM   3272  C CA  . GLN A 1 408 ? -20.285 -28.356 -31.465 1.00 40.82  ? 408 GLN A CA  1 
ATOM   3273  C C   . GLN A 1 408 ? -20.881 -29.039 -30.244 1.00 43.81  ? 408 GLN A C   1 
ATOM   3274  O O   . GLN A 1 408 ? -21.396 -30.136 -30.374 1.00 38.13  ? 408 GLN A O   1 
ATOM   3275  C CB  . GLN A 1 408 ? -18.794 -28.656 -31.537 1.00 42.83  ? 408 GLN A CB  1 
ATOM   3276  C CG  . GLN A 1 408 ? -18.231 -28.493 -32.941 1.00 42.62  ? 408 GLN A CG  1 
ATOM   3277  C CD  . GLN A 1 408 ? -16.745 -28.707 -32.940 1.00 51.52  ? 408 GLN A CD  1 
ATOM   3278  O OE1 . GLN A 1 408 ? -16.217 -29.388 -32.063 1.00 79.57  ? 408 GLN A OE1 1 
ATOM   3279  N NE2 . GLN A 1 408 ? -16.052 -28.043 -33.852 1.00 49.74  ? 408 GLN A NE2 1 
ATOM   3280  N N   . ALA A 1 409 ? -20.775 -28.422 -29.060 1.00 44.18  ? 409 ALA A N   1 
ATOM   3281  C CA  . ALA A 1 409 ? -21.146 -29.117 -27.841 1.00 41.12  ? 409 ALA A CA  1 
ATOM   3282  C C   . ALA A 1 409 ? -22.662 -29.127 -27.676 1.00 43.26  ? 409 ALA A C   1 
ATOM   3283  O O   . ALA A 1 409 ? -23.241 -30.050 -27.100 1.00 44.52  ? 409 ALA A O   1 
ATOM   3284  C CB  . ALA A 1 409 ? -20.491 -28.471 -26.652 1.00 43.46  ? 409 ALA A CB  1 
ATOM   3285  N N   . ILE A 1 410 ? -23.316 -28.065 -28.118 1.00 38.93  ? 410 ILE A N   1 
ATOM   3286  C CA  . ILE A 1 410 ? -24.769 -28.066 -28.136 1.00 42.72  ? 410 ILE A CA  1 
ATOM   3287  C C   . ILE A 1 410 ? -25.255 -29.188 -29.062 1.00 40.63  ? 410 ILE A C   1 
ATOM   3288  O O   . ILE A 1 410 ? -26.152 -29.932 -28.726 1.00 42.76  ? 410 ILE A O   1 
ATOM   3289  C CB  . ILE A 1 410 ? -25.281 -26.668 -28.552 1.00 42.85  ? 410 ILE A CB  1 
ATOM   3290  C CG1 . ILE A 1 410 ? -25.030 -25.632 -27.458 1.00 43.59  ? 410 ILE A CG1 1 
ATOM   3291  C CG2 . ILE A 1 410 ? -26.746 -26.702 -28.919 1.00 42.92  ? 410 ILE A CG2 1 
ATOM   3292  C CD1 . ILE A 1 410 ? -24.995 -24.199 -27.948 1.00 45.39  ? 410 ILE A CD1 1 
ATOM   3293  N N   . LEU A 1 411 ? -24.663 -29.319 -30.244 1.00 41.16  ? 411 LEU A N   1 
ATOM   3294  C CA  . LEU A 1 411 ? -25.198 -30.222 -31.245 1.00 42.69  ? 411 LEU A CA  1 
ATOM   3295  C C   . LEU A 1 411 ? -25.054 -31.667 -30.773 1.00 43.57  ? 411 LEU A C   1 
ATOM   3296  O O   . LEU A 1 411 ? -26.002 -32.434 -30.806 1.00 39.42  ? 411 LEU A O   1 
ATOM   3297  C CB  . LEU A 1 411 ? -24.472 -30.007 -32.573 1.00 41.69  ? 411 LEU A CB  1 
ATOM   3298  C CG  . LEU A 1 411 ? -24.892 -28.758 -33.324 1.00 47.99  ? 411 LEU A CG  1 
ATOM   3299  C CD1 . LEU A 1 411 ? -24.080 -28.615 -34.592 1.00 51.48  ? 411 LEU A CD1 1 
ATOM   3300  C CD2 . LEU A 1 411 ? -26.375 -28.807 -33.637 1.00 49.18  ? 411 LEU A CD2 1 
ATOM   3301  N N   . VAL A 1 412 ? -23.864 -31.993 -30.288 1.00 40.99  ? 412 VAL A N   1 
ATOM   3302  C CA  . VAL A 1 412 ? -23.509 -33.340 -29.919 1.00 43.96  ? 412 VAL A CA  1 
ATOM   3303  C C   . VAL A 1 412 ? -24.333 -33.788 -28.708 1.00 40.51  ? 412 VAL A C   1 
ATOM   3304  O O   . VAL A 1 412 ? -24.606 -34.979 -28.533 1.00 35.94  ? 412 VAL A O   1 
ATOM   3305  C CB  . VAL A 1 412 ? -21.979 -33.409 -29.724 1.00 47.65  ? 412 VAL A CB  1 
ATOM   3306  C CG1 . VAL A 1 412 ? -21.540 -34.508 -28.787 1.00 58.27  ? 412 VAL A CG1 1 
ATOM   3307  C CG2 . VAL A 1 412 ? -21.274 -33.551 -31.075 1.00 50.32  ? 412 VAL A CG2 1 
ATOM   3308  N N   . ARG A 1 413 ? -24.725 -32.859 -27.847 1.00 38.92  ? 413 ARG A N   1 
ATOM   3309  C CA  . ARG A 1 413 ? -25.585 -33.245 -26.740 1.00 46.80  ? 413 ARG A CA  1 
ATOM   3310  C C   . ARG A 1 413 ? -27.024 -33.368 -27.246 1.00 50.17  ? 413 ARG A C   1 
ATOM   3311  O O   . ARG A 1 413 ? -27.820 -34.067 -26.627 1.00 53.90  ? 413 ARG A O   1 
ATOM   3312  C CB  . ARG A 1 413 ? -25.441 -32.289 -25.554 1.00 46.53  ? 413 ARG A CB  1 
ATOM   3313  C CG  . ARG A 1 413 ? -24.050 -32.307 -24.926 1.00 47.50  ? 413 ARG A CG  1 
ATOM   3314  C CD  . ARG A 1 413 ? -23.874 -33.268 -23.770 1.00 45.51  ? 413 ARG A CD  1 
ATOM   3315  N NE  . ARG A 1 413 ? -24.312 -34.626 -24.053 1.00 51.72  ? 413 ARG A NE  1 
ATOM   3316  C CZ  . ARG A 1 413 ? -23.635 -35.484 -24.794 1.00 48.55  ? 413 ARG A CZ  1 
ATOM   3317  N NH1 . ARG A 1 413 ? -22.412 -35.178 -25.190 1.00 48.04  ? 413 ARG A NH1 1 
ATOM   3318  N NH2 . ARG A 1 413 ? -24.181 -36.639 -25.126 1.00 47.87  ? 413 ARG A NH2 1 
ATOM   3319  N N   . GLY A 1 414 ? -27.327 -32.735 -28.394 1.00 48.17  ? 414 GLY A N   1 
ATOM   3320  C CA  . GLY A 1 414 ? -28.564 -32.981 -29.124 1.00 49.44  ? 414 GLY A CA  1 
ATOM   3321  C C   . GLY A 1 414 ? -28.614 -34.385 -29.743 1.00 52.20  ? 414 GLY A C   1 
ATOM   3322  O O   . GLY A 1 414 ? -29.616 -35.089 -29.628 1.00 55.18  ? 414 GLY A O   1 
ATOM   3323  N N   . TYR A 1 415 ? -27.507 -34.793 -30.371 1.00 46.78  ? 415 TYR A N   1 
ATOM   3324  C CA  . TYR A 1 415 ? -27.396 -36.093 -31.008 1.00 49.06  ? 415 TYR A CA  1 
ATOM   3325  C C   . TYR A 1 415 ? -27.322 -37.221 -29.975 1.00 46.91  ? 415 TYR A C   1 
ATOM   3326  O O   . TYR A 1 415 ? -27.489 -38.385 -30.312 1.00 46.95  ? 415 TYR A O   1 
ATOM   3327  C CB  . TYR A 1 415 ? -26.102 -36.204 -31.824 1.00 50.21  ? 415 TYR A CB  1 
ATOM   3328  C CG  . TYR A 1 415 ? -25.881 -35.242 -32.961 1.00 45.67  ? 415 TYR A CG  1 
ATOM   3329  C CD1 . TYR A 1 415 ? -26.858 -34.378 -33.414 1.00 47.82  ? 415 TYR A CD1 1 
ATOM   3330  C CD2 . TYR A 1 415 ? -24.682 -35.266 -33.646 1.00 46.60  ? 415 TYR A CD2 1 
ATOM   3331  C CE1 . TYR A 1 415 ? -26.630 -33.522 -34.483 1.00 49.94  ? 415 TYR A CE1 1 
ATOM   3332  C CE2 . TYR A 1 415 ? -24.441 -34.428 -34.715 1.00 48.84  ? 415 TYR A CE2 1 
ATOM   3333  C CZ  . TYR A 1 415 ? -25.413 -33.547 -35.132 1.00 50.77  ? 415 TYR A CZ  1 
ATOM   3334  O OH  . TYR A 1 415 ? -25.132 -32.747 -36.201 1.00 54.91  ? 415 TYR A OH  1 
ATOM   3335  N N   . MET A 1 416 ? -26.925 -36.896 -28.742 1.00 51.17  ? 416 MET A N   1 
ATOM   3336  C CA  . MET A 1 416 ? -26.725 -37.879 -27.676 1.00 46.31  ? 416 MET A CA  1 
ATOM   3337  C C   . MET A 1 416 ? -25.526 -38.794 -27.935 1.00 46.24  ? 416 MET A C   1 
ATOM   3338  O O   . MET A 1 416 ? -25.542 -39.951 -27.531 1.00 45.14  ? 416 MET A O   1 
ATOM   3339  C CB  . MET A 1 416 ? -27.990 -38.716 -27.464 1.00 49.46  ? 416 MET A CB  1 
ATOM   3340  C CG  . MET A 1 416 ? -28.972 -37.988 -26.592 1.00 57.72  ? 416 MET A CG  1 
ATOM   3341  S SD  . MET A 1 416 ? -30.692 -38.503 -26.776 1.00 63.99  ? 416 MET A SD  1 
ATOM   3342  C CE  . MET A 1 416 ? -31.467 -37.013 -26.157 1.00 78.99  ? 416 MET A CE  1 
ATOM   3343  N N   . LEU A 1 417 ? -24.439 -38.284 -28.540 1.00 42.06  ? 417 LEU A N   1 
ATOM   3344  C CA  . LEU A 1 417 ? -23.244 -39.105 -28.652 1.00 38.14  ? 417 LEU A CA  1 
ATOM   3345  C C   . LEU A 1 417 ? -22.741 -39.540 -27.269 1.00 47.61  ? 417 LEU A C   1 
ATOM   3346  O O   . LEU A 1 417 ? -22.928 -38.869 -26.247 1.00 46.58  ? 417 LEU A O   1 
ATOM   3347  C CB  . LEU A 1 417 ? -22.166 -38.344 -29.417 1.00 41.16  ? 417 LEU A CB  1 
ATOM   3348  C CG  . LEU A 1 417 ? -22.552 -37.940 -30.844 1.00 44.22  ? 417 LEU A CG  1 
ATOM   3349  C CD1 . LEU A 1 417 ? -21.319 -37.718 -31.710 1.00 41.89  ? 417 LEU A CD1 1 
ATOM   3350  C CD2 . LEU A 1 417 ? -23.495 -38.950 -31.491 1.00 42.51  ? 417 LEU A CD2 1 
ATOM   3351  N N   . PRO A 1 418 ? -22.162 -40.744 -27.165 1.00 46.81  ? 418 PRO A N   1 
ATOM   3352  C CA  . PRO A 1 418 ? -21.698 -41.251 -25.884 1.00 46.53  ? 418 PRO A CA  1 
ATOM   3353  C C   . PRO A 1 418 ? -20.268 -40.805 -25.595 1.00 49.97  ? 418 PRO A C   1 
ATOM   3354  O O   . PRO A 1 418 ? -19.589 -40.192 -26.436 1.00 48.74  ? 418 PRO A O   1 
ATOM   3355  C CB  . PRO A 1 418 ? -21.776 -42.772 -26.121 1.00 48.84  ? 418 PRO A CB  1 
ATOM   3356  C CG  . PRO A 1 418 ? -21.414 -42.942 -27.582 1.00 44.37  ? 418 PRO A CG  1 
ATOM   3357  C CD  . PRO A 1 418 ? -21.999 -41.720 -28.256 1.00 45.18  ? 418 PRO A CD  1 
ATOM   3358  N N   . ILE A 1 419 ? -19.812 -41.202 -24.405 1.00 47.62  ? 419 ILE A N   1 
ATOM   3359  C CA  . ILE A 1 419 ? -18.514 -40.831 -23.871 1.00 46.50  ? 419 ILE A CA  1 
ATOM   3360  C C   . ILE A 1 419 ? -17.442 -41.267 -24.847 1.00 41.82  ? 419 ILE A C   1 
ATOM   3361  O O   . ILE A 1 419 ? -17.512 -42.347 -25.404 1.00 49.95  ? 419 ILE A O   1 
ATOM   3362  C CB  . ILE A 1 419 ? -18.334 -41.443 -22.463 1.00 49.99  ? 419 ILE A CB  1 
ATOM   3363  C CG1 . ILE A 1 419 ? -17.157 -40.836 -21.701 1.00 52.40  ? 419 ILE A CG1 1 
ATOM   3364  C CG2 . ILE A 1 419 ? -18.243 -42.962 -22.511 1.00 47.43  ? 419 ILE A CG2 1 
ATOM   3365  C CD1 . ILE A 1 419 ? -17.150 -41.209 -20.224 1.00 54.80  ? 419 ILE A CD1 1 
ATOM   3366  N N   . GLU A 1 420 ? -16.420 -40.437 -24.995 1.00 41.84  ? 420 GLU A N   1 
ATOM   3367  C CA  . GLU A 1 420 ? -15.237 -40.788 -25.762 1.00 44.48  ? 420 GLU A CA  1 
ATOM   3368  C C   . GLU A 1 420 ? -14.312 -41.652 -24.893 1.00 48.67  ? 420 GLU A C   1 
ATOM   3369  O O   . GLU A 1 420 ? -13.904 -41.227 -23.816 1.00 56.10  ? 420 GLU A O   1 
ATOM   3370  C CB  . GLU A 1 420 ? -14.656 -39.481 -26.316 1.00 38.27  ? 420 GLU A CB  1 
ATOM   3371  C CG  . GLU A 1 420 ? -13.262 -39.577 -26.891 1.00 50.58  ? 420 GLU A CG  1 
ATOM   3372  C CD  . GLU A 1 420 ? -12.805 -38.369 -27.695 1.00 55.93  ? 420 GLU A CD  1 
ATOM   3373  O OE1 . GLU A 1 420 ? -11.653 -38.371 -28.147 1.00 52.93  ? 420 GLU A OE1 1 
ATOM   3374  O OE2 . GLU A 1 420 ? -13.607 -37.428 -27.869 1.00 61.88  ? 420 GLU A OE2 1 
ATOM   3375  N N   . ARG A 1 421 ? -13.997 -42.873 -25.363 1.00 53.33  ? 421 ARG A N   1 
ATOM   3376  C CA  . ARG A 1 421 ? -13.194 -43.857 -24.640 1.00 54.54  ? 421 ARG A CA  1 
ATOM   3377  C C   . ARG A 1 421 ? -12.449 -44.766 -25.630 1.00 51.00  ? 421 ARG A C   1 
ATOM   3378  O O   . ARG A 1 421 ? -12.771 -45.923 -25.800 1.00 52.80  ? 421 ARG A O   1 
ATOM   3379  C CB  . ARG A 1 421 ? -14.052 -44.675 -23.665 1.00 60.98  ? 421 ARG A CB  1 
ATOM   3380  C CG  . ARG A 1 421 ? -13.270 -45.348 -22.532 1.00 82.72  ? 421 ARG A CG  1 
ATOM   3381  C CD  . ARG A 1 421 ? -14.100 -46.169 -21.533 1.00 99.77  ? 421 ARG A CD  1 
ATOM   3382  N NE  . ARG A 1 421 ? -14.473 -47.514 -22.009 1.00 124.78 ? 421 ARG A NE  1 
ATOM   3383  C CZ  . ARG A 1 421 ? -15.433 -48.308 -21.505 1.00 111.29 ? 421 ARG A CZ  1 
ATOM   3384  N NH1 . ARG A 1 421 ? -16.235 -47.879 -20.544 1.00 86.55  ? 421 ARG A NH1 1 
ATOM   3385  N NH2 . ARG A 1 421 ? -15.606 -49.533 -21.988 1.00 100.54 ? 421 ARG A NH2 1 
ATOM   3386  N N   . PRO A 1 422 ? -11.364 -44.302 -26.276 1.00 46.92  ? 422 PRO A N   1 
ATOM   3387  C CA  . PRO A 1 422 ? -10.557 -45.156 -27.124 1.00 49.40  ? 422 PRO A CA  1 
ATOM   3388  C C   . PRO A 1 422 ? -9.760  -46.115 -26.254 1.00 51.51  ? 422 PRO A C   1 
ATOM   3389  O O   . PRO A 1 422 ? -9.767  -46.024 -25.033 1.00 54.68  ? 422 PRO A O   1 
ATOM   3390  C CB  . PRO A 1 422 ? -9.607  -44.226 -27.898 1.00 48.38  ? 422 PRO A CB  1 
ATOM   3391  C CG  . PRO A 1 422 ? -9.680  -42.883 -27.188 1.00 52.35  ? 422 PRO A CG  1 
ATOM   3392  C CD  . PRO A 1 422 ? -10.790 -42.957 -26.151 1.00 52.59  ? 422 PRO A CD  1 
ATOM   3393  N N   . LYS A 1 423 ? -9.125  -47.060 -26.934 1.00 54.72  ? 423 LYS A N   1 
ATOM   3394  C CA  . LYS A 1 423 ? -8.270  -48.054 -26.326 1.00 50.69  ? 423 LYS A CA  1 
ATOM   3395  C C   . LYS A 1 423 ? -6.829  -47.602 -26.530 1.00 51.98  ? 423 LYS A C   1 
ATOM   3396  O O   . LYS A 1 423 ? -6.437  -47.179 -27.628 1.00 49.38  ? 423 LYS A O   1 
ATOM   3397  C CB  . LYS A 1 423 ? -8.578  -49.405 -26.975 1.00 58.92  ? 423 LYS A CB  1 
ATOM   3398  C CG  . LYS A 1 423 ? -7.698  -50.564 -26.544 1.00 65.41  ? 423 LYS A CG  1 
ATOM   3399  C CD  . LYS A 1 423 ? -7.795  -50.849 -25.073 1.00 69.12  ? 423 LYS A CD  1 
ATOM   3400  C CE  . LYS A 1 423 ? -6.911  -51.993 -24.632 1.00 65.81  ? 423 LYS A CE  1 
ATOM   3401  N NZ  . LYS A 1 423 ? -7.283  -52.419 -23.262 1.00 72.10  ? 423 LYS A NZ  1 
ATOM   3402  N N   . SER A 1 424 ? -6.051  -47.640 -25.443 1.00 53.16  ? 424 SER A N   1 
ATOM   3403  C CA  . SER A 1 424 ? -4.618  -47.398 -25.527 1.00 50.88  ? 424 SER A CA  1 
ATOM   3404  C C   . SER A 1 424 ? -3.918  -48.739 -25.713 1.00 42.09  ? 424 SER A C   1 
ATOM   3405  O O   . SER A 1 424 ? -4.387  -49.757 -25.225 1.00 44.76  ? 424 SER A O   1 
ATOM   3406  C CB  . SER A 1 424 ? -4.073  -46.623 -24.328 1.00 49.50  ? 424 SER A CB  1 
ATOM   3407  O OG  . SER A 1 424 ? -4.138  -47.373 -23.113 1.00 51.44  ? 424 SER A OG  1 
ATOM   3408  N N   . ILE A 1 425 ? -2.794  -48.722 -26.426 1.00 45.11  ? 425 ILE A N   1 
ATOM   3409  C CA  . ILE A 1 425 ? -1.973  -49.911 -26.573 1.00 50.59  ? 425 ILE A CA  1 
ATOM   3410  C C   . ILE A 1 425 ? -0.616  -49.611 -25.958 1.00 46.55  ? 425 ILE A C   1 
ATOM   3411  O O   . ILE A 1 425 ? -0.213  -48.443 -25.867 1.00 48.52  ? 425 ILE A O   1 
ATOM   3412  C CB  . ILE A 1 425 ? -1.849  -50.346 -28.053 1.00 50.83  ? 425 ILE A CB  1 
ATOM   3413  C CG1 . ILE A 1 425 ? -0.941  -49.404 -28.843 1.00 55.17  ? 425 ILE A CG1 1 
ATOM   3414  C CG2 . ILE A 1 425 ? -3.227  -50.484 -28.694 1.00 52.21  ? 425 ILE A CG2 1 
ATOM   3415  C CD1 . ILE A 1 425 ? -0.933  -49.648 -30.344 1.00 64.07  ? 425 ILE A CD1 1 
ATOM   3416  N N   . THR A 1 426 ? 0.073   -50.698 -25.600 1.00 45.37  ? 426 THR A N   1 
ATOM   3417  C CA  . THR A 1 426 ? 1.419   -50.656 -25.067 1.00 46.08  ? 426 THR A CA  1 
ATOM   3418  C C   . THR A 1 426 ? 2.448   -50.977 -26.144 1.00 46.78  ? 426 THR A C   1 
ATOM   3419  O O   . THR A 1 426 ? 2.195   -51.776 -27.042 1.00 45.15  ? 426 THR A O   1 
ATOM   3420  C CB  . THR A 1 426 ? 1.561   -51.673 -23.928 1.00 43.83  ? 426 THR A CB  1 
ATOM   3421  O OG1 . THR A 1 426 ? 1.401   -52.975 -24.505 1.00 46.89  ? 426 THR A OG1 1 
ATOM   3422  C CG2 . THR A 1 426 ? 0.529   -51.434 -22.846 1.00 37.92  ? 426 THR A CG2 1 
ATOM   3423  N N   . THR A 1 427 ? 3.630   -50.393 -25.960 1.00 41.22  ? 427 THR A N   1 
ATOM   3424  C CA  . THR A 1 427 ? 4.818   -50.717 -26.715 1.00 50.25  ? 427 THR A CA  1 
ATOM   3425  C C   . THR A 1 427 ? 5.162   -52.210 -26.598 1.00 53.11  ? 427 THR A C   1 
ATOM   3426  O O   . THR A 1 427 ? 5.607   -52.807 -27.583 1.00 50.01  ? 427 THR A O   1 
ATOM   3427  C CB  . THR A 1 427 ? 5.945   -49.779 -26.283 1.00 44.80  ? 427 THR A CB  1 
ATOM   3428  O OG1 . THR A 1 427 ? 5.488   -48.452 -26.548 1.00 45.46  ? 427 THR A OG1 1 
ATOM   3429  C CG2 . THR A 1 427 ? 7.248   -50.027 -27.007 1.00 49.36  ? 427 THR A CG2 1 
ATOM   3430  N N   . ARG A 1 428 ? 4.972   -52.802 -25.412 1.00 46.07  ? 428 ARG A N   1 
ATOM   3431  C CA  . ARG A 1 428 ? 5.307   -54.201 -25.187 1.00 47.78  ? 428 ARG A CA  1 
ATOM   3432  C C   . ARG A 1 428 ? 4.481   -55.068 -26.135 1.00 45.34  ? 428 ARG A C   1 
ATOM   3433  O O   . ARG A 1 428 ? 5.046   -55.905 -26.812 1.00 47.41  ? 428 ARG A O   1 
ATOM   3434  C CB  . ARG A 1 428 ? 5.086   -54.612 -23.725 1.00 50.35  ? 428 ARG A CB  1 
ATOM   3435  C CG  . ARG A 1 428 ? 5.342   -56.081 -23.408 1.00 49.61  ? 428 ARG A CG  1 
ATOM   3436  C CD  . ARG A 1 428 ? 4.370   -56.621 -22.362 1.00 48.84  ? 428 ARG A CD  1 
ATOM   3437  N NE  . ARG A 1 428 ? 2.964   -56.509 -22.783 1.00 55.61  ? 428 ARG A NE  1 
ATOM   3438  C CZ  . ARG A 1 428 ? 2.315   -57.309 -23.660 1.00 54.65  ? 428 ARG A CZ  1 
ATOM   3439  N NH1 . ARG A 1 428 ? 2.865   -58.429 -24.100 1.00 51.24  ? 428 ARG A NH1 1 
ATOM   3440  N NH2 . ARG A 1 428 ? 1.075   -57.023 -24.053 1.00 48.51  ? 428 ARG A NH2 1 
ATOM   3441  N N   . TRP A 1 429 ? 3.175   -54.799 -26.232 1.00 46.95  ? 429 TRP A N   1 
ATOM   3442  C CA  . TRP A 1 429 ? 2.266   -55.541 -27.090 1.00 42.24  ? 429 TRP A CA  1 
ATOM   3443  C C   . TRP A 1 429 ? 2.690   -55.394 -28.548 1.00 51.04  ? 429 TRP A C   1 
ATOM   3444  O O   . TRP A 1 429 ? 2.868   -56.391 -29.244 1.00 51.73  ? 429 TRP A O   1 
ATOM   3445  C CB  . TRP A 1 429 ? 0.833   -55.031 -26.867 1.00 48.59  ? 429 TRP A CB  1 
ATOM   3446  C CG  . TRP A 1 429 ? -0.226  -55.693 -27.685 1.00 49.82  ? 429 TRP A CG  1 
ATOM   3447  C CD1 . TRP A 1 429 ? -0.800  -56.909 -27.446 1.00 56.88  ? 429 TRP A CD1 1 
ATOM   3448  C CD2 . TRP A 1 429 ? -0.846  -55.187 -28.882 1.00 50.22  ? 429 TRP A CD2 1 
ATOM   3449  N NE1 . TRP A 1 429 ? -1.735  -57.190 -28.405 1.00 58.67  ? 429 TRP A NE1 1 
ATOM   3450  C CE2 . TRP A 1 429 ? -1.782  -56.158 -29.303 1.00 49.68  ? 429 TRP A CE2 1 
ATOM   3451  C CE3 . TRP A 1 429 ? -0.704  -54.023 -29.641 1.00 49.97  ? 429 TRP A CE3 1 
ATOM   3452  C CZ2 . TRP A 1 429 ? -2.571  -55.994 -30.434 1.00 45.01  ? 429 TRP A CZ2 1 
ATOM   3453  C CZ3 . TRP A 1 429 ? -1.467  -53.866 -30.778 1.00 50.80  ? 429 TRP A CZ3 1 
ATOM   3454  C CH2 . TRP A 1 429 ? -2.410  -54.829 -31.152 1.00 50.22  ? 429 TRP A CH2 1 
ATOM   3455  N N   . VAL A 1 430 ? 2.848   -54.134 -28.982 1.00 47.65  ? 430 VAL A N   1 
ATOM   3456  C CA  . VAL A 1 430 ? 3.367   -53.789 -30.290 1.00 50.60  ? 430 VAL A CA  1 
ATOM   3457  C C   . VAL A 1 430 ? 4.619   -54.615 -30.599 1.00 53.67  ? 430 VAL A C   1 
ATOM   3458  O O   . VAL A 1 430 ? 4.693   -55.179 -31.674 1.00 56.19  ? 430 VAL A O   1 
ATOM   3459  C CB  . VAL A 1 430 ? 3.639   -52.273 -30.398 1.00 51.99  ? 430 VAL A CB  1 
ATOM   3460  C CG1 . VAL A 1 430 ? 4.528   -51.919 -31.576 1.00 49.87  ? 430 VAL A CG1 1 
ATOM   3461  C CG2 . VAL A 1 430 ? 2.355   -51.472 -30.461 1.00 54.02  ? 430 VAL A CG2 1 
ATOM   3462  N N   . LYS A 1 431 ? 5.604   -54.694 -29.690 1.00 57.45  ? 431 LYS A N   1 
ATOM   3463  C CA  . LYS A 1 431 ? 6.812   -55.478 -29.954 1.00 59.37  ? 431 LYS A CA  1 
ATOM   3464  C C   . LYS A 1 431 ? 6.521   -56.980 -30.056 1.00 63.07  ? 431 LYS A C   1 
ATOM   3465  O O   . LYS A 1 431 ? 7.327   -57.736 -30.598 1.00 56.77  ? 431 LYS A O   1 
ATOM   3466  C CB  . LYS A 1 431 ? 7.864   -55.339 -28.848 1.00 56.43  ? 431 LYS A CB  1 
ATOM   3467  C CG  . LYS A 1 431 ? 8.769   -54.117 -28.940 1.00 60.28  ? 431 LYS A CG  1 
ATOM   3468  C CD  . LYS A 1 431 ? 9.924   -54.182 -27.969 1.00 62.78  ? 431 LYS A CD  1 
ATOM   3469  C CE  . LYS A 1 431 ? 10.231  -52.827 -27.379 1.00 80.84  ? 431 LYS A CE  1 
ATOM   3470  N NZ  . LYS A 1 431 ? 11.072  -52.918 -26.161 1.00 91.65  ? 431 LYS A NZ  1 
ATOM   3471  N N   . GLU A 1 432 ? 5.420   -57.426 -29.442 1.00 60.03  ? 432 GLU A N   1 
ATOM   3472  C CA  . GLU A 1 432 ? 5.105   -58.840 -29.396 1.00 66.16  ? 432 GLU A CA  1 
ATOM   3473  C C   . GLU A 1 432 ? 4.475   -59.266 -30.723 1.00 58.04  ? 432 GLU A C   1 
ATOM   3474  O O   . GLU A 1 432 ? 4.712   -60.378 -31.156 1.00 57.92  ? 432 GLU A O   1 
ATOM   3475  C CB  . GLU A 1 432 ? 4.178   -59.139 -28.215 1.00 68.50  ? 432 GLU A CB  1 
ATOM   3476  C CG  . GLU A 1 432 ? 3.974   -60.619 -27.902 1.00 78.59  ? 432 GLU A CG  1 
ATOM   3477  C CD  . GLU A 1 432 ? 2.921   -60.905 -26.826 1.00 89.33  ? 432 GLU A CD  1 
ATOM   3478  O OE1 . GLU A 1 432 ? 3.292   -61.450 -25.743 1.00 89.03  ? 432 GLU A OE1 1 
ATOM   3479  O OE2 . GLU A 1 432 ? 1.722   -60.582 -27.054 1.00 77.90  ? 432 GLU A OE2 1 
ATOM   3480  N N   . VAL A 1 433 ? 3.639   -58.414 -31.326 1.00 49.43  ? 433 VAL A N   1 
ATOM   3481  C CA  . VAL A 1 433 ? 2.697   -58.878 -32.326 1.00 52.54  ? 433 VAL A CA  1 
ATOM   3482  C C   . VAL A 1 433 ? 2.940   -58.199 -33.673 1.00 50.95  ? 433 VAL A C   1 
ATOM   3483  O O   . VAL A 1 433 ? 2.304   -58.542 -34.651 1.00 58.58  ? 433 VAL A O   1 
ATOM   3484  C CB  . VAL A 1 433 ? 1.244   -58.669 -31.856 1.00 48.54  ? 433 VAL A CB  1 
ATOM   3485  C CG1 . VAL A 1 433 ? 0.984   -59.259 -30.483 1.00 50.54  ? 433 VAL A CG1 1 
ATOM   3486  C CG2 . VAL A 1 433 ? 0.838   -57.206 -31.876 1.00 54.07  ? 433 VAL A CG2 1 
ATOM   3487  N N   . ALA A 1 434 ? 3.825   -57.213 -33.736 1.00 53.06  ? 434 ALA A N   1 
ATOM   3488  C CA  . ALA A 1 434 ? 3.871   -56.346 -34.902 1.00 58.11  ? 434 ALA A CA  1 
ATOM   3489  C C   . ALA A 1 434 ? 4.169   -57.145 -36.177 1.00 55.76  ? 434 ALA A C   1 
ATOM   3490  O O   . ALA A 1 434 ? 3.442   -56.996 -37.163 1.00 46.74  ? 434 ALA A O   1 
ATOM   3491  C CB  . ALA A 1 434 ? 4.867   -55.244 -34.692 1.00 54.30  ? 434 ALA A CB  1 
ATOM   3492  N N   . GLU A 1 435 ? 5.232   -57.966 -36.147 1.00 54.20  ? 435 GLU A N   1 
ATOM   3493  C CA  . GLU A 1 435 ? 5.605   -58.831 -37.267 1.00 56.06  ? 435 GLU A CA  1 
ATOM   3494  C C   . GLU A 1 435 ? 4.413   -59.649 -37.763 1.00 52.09  ? 435 GLU A C   1 
ATOM   3495  O O   . GLU A 1 435 ? 4.209   -59.720 -38.959 1.00 52.46  ? 435 GLU A O   1 
ATOM   3496  C CB  . GLU A 1 435 ? 6.790   -59.730 -36.910 1.00 53.69  ? 435 GLU A CB  1 
ATOM   3497  C CG  . GLU A 1 435 ? 8.124   -59.017 -37.012 1.00 59.11  ? 435 GLU A CG  1 
ATOM   3498  C CD  . GLU A 1 435 ? 9.213   -59.504 -36.063 1.00 74.59  ? 435 GLU A CD  1 
ATOM   3499  O OE1 . GLU A 1 435 ? 10.359  -59.722 -36.542 1.00 73.05  ? 435 GLU A OE1 1 
ATOM   3500  O OE2 . GLU A 1 435 ? 8.933   -59.643 -34.830 1.00 73.94  ? 435 GLU A OE2 1 
ATOM   3501  N N   . SER A 1 436 ? 3.574   -60.173 -36.863 1.00 56.71  ? 436 SER A N   1 
ATOM   3502  C CA  . SER A 1 436 ? 2.448   -61.022 -37.244 1.00 59.11  ? 436 SER A CA  1 
ATOM   3503  C C   . SER A 1 436 ? 1.253   -60.246 -37.834 1.00 63.92  ? 436 SER A C   1 
ATOM   3504  O O   . SER A 1 436 ? 0.271   -60.860 -38.272 1.00 56.14  ? 436 SER A O   1 
ATOM   3505  C CB  . SER A 1 436 ? 2.011   -61.851 -36.048 1.00 57.58  ? 436 SER A CB  1 
ATOM   3506  O OG  . SER A 1 436 ? 1.072   -61.128 -35.248 1.00 61.70  ? 436 SER A OG  1 
ATOM   3507  N N   . LEU A 1 437 ? 1.298   -58.904 -37.823 1.00 60.76  ? 437 LEU A N   1 
ATOM   3508  C CA  . LEU A 1 437 ? 0.172   -58.095 -38.269 1.00 55.43  ? 437 LEU A CA  1 
ATOM   3509  C C   . LEU A 1 437 ? 0.278   -57.818 -39.765 1.00 49.71  ? 437 LEU A C   1 
ATOM   3510  O O   . LEU A 1 437 ? 1.353   -57.580 -40.324 1.00 48.28  ? 437 LEU A O   1 
ATOM   3511  C CB  . LEU A 1 437 ? 0.109   -56.750 -37.527 1.00 57.60  ? 437 LEU A CB  1 
ATOM   3512  C CG  . LEU A 1 437 ? -0.344  -56.753 -36.065 1.00 60.33  ? 437 LEU A CG  1 
ATOM   3513  C CD1 . LEU A 1 437 ? -0.222  -55.346 -35.489 1.00 56.80  ? 437 LEU A CD1 1 
ATOM   3514  C CD2 . LEU A 1 437 ? -1.771  -57.265 -35.909 1.00 56.51  ? 437 LEU A CD2 1 
ATOM   3515  N N   . PRO A 1 438 ? -0.880  -57.711 -40.430 1.00 44.10  ? 438 PRO A N   1 
ATOM   3516  C CA  . PRO A 1 438 ? -0.906  -57.352 -41.840 1.00 52.20  ? 438 PRO A CA  1 
ATOM   3517  C C   . PRO A 1 438 ? -0.595  -55.876 -42.076 1.00 58.36  ? 438 PRO A C   1 
ATOM   3518  O O   . PRO A 1 438 ? -1.069  -55.004 -41.353 1.00 52.03  ? 438 PRO A O   1 
ATOM   3519  C CB  . PRO A 1 438 ? -2.359  -57.671 -42.249 1.00 51.44  ? 438 PRO A CB  1 
ATOM   3520  C CG  . PRO A 1 438 ? -3.186  -57.542 -40.969 1.00 48.69  ? 438 PRO A CG  1 
ATOM   3521  C CD  . PRO A 1 438 ? -2.224  -57.879 -39.847 1.00 47.39  ? 438 PRO A CD  1 
ATOM   3522  N N   . VAL A 1 439 ? 0.172   -55.617 -43.134 1.00 55.86  ? 439 VAL A N   1 
ATOM   3523  C CA  . VAL A 1 439 ? 0.375   -54.276 -43.644 1.00 52.72  ? 439 VAL A CA  1 
ATOM   3524  C C   . VAL A 1 439 ? -0.939  -53.736 -44.205 1.00 60.59  ? 439 VAL A C   1 
ATOM   3525  O O   . VAL A 1 439 ? -1.645  -54.463 -44.894 1.00 58.50  ? 439 VAL A O   1 
ATOM   3526  C CB  . VAL A 1 439 ? 1.491   -54.279 -44.699 1.00 49.86  ? 439 VAL A CB  1 
ATOM   3527  C CG1 . VAL A 1 439 ? 1.647   -52.919 -45.357 1.00 51.69  ? 439 VAL A CG1 1 
ATOM   3528  C CG2 . VAL A 1 439 ? 2.801   -54.721 -44.065 1.00 52.02  ? 439 VAL A CG2 1 
ATOM   3529  N N   . ALA A 1 440 ? -1.256  -52.467 -43.876 1.00 63.76  ? 440 ALA A N   1 
ATOM   3530  C CA  . ALA A 1 440 ? -2.490  -51.821 -44.299 1.00 65.00  ? 440 ALA A CA  1 
ATOM   3531  C C   . ALA A 1 440 ? -2.517  -51.766 -45.820 1.00 71.14  ? 440 ALA A C   1 
ATOM   3532  O O   . ALA A 1 440 ? -1.595  -51.215 -46.418 1.00 72.93  ? 440 ALA A O   1 
ATOM   3533  C CB  . ALA A 1 440 ? -2.609  -50.424 -43.724 1.00 59.25  ? 440 ALA A CB  1 
ATOM   3534  N N   . GLY A 1 441 ? -3.565  -52.366 -46.404 1.00 80.31  ? 441 GLY A N   1 
ATOM   3535  C CA  . GLY A 1 441 ? -3.774  -52.394 -47.844 1.00 89.11  ? 441 GLY A CA  1 
ATOM   3536  C C   . GLY A 1 441 ? -2.984  -53.489 -48.569 1.00 92.74  ? 441 GLY A C   1 
ATOM   3537  O O   . GLY A 1 441 ? -2.596  -53.281 -49.723 1.00 90.81  ? 441 GLY A O   1 
ATOM   3538  N N   . SER A 1 442 ? -2.759  -54.642 -47.902 1.00 87.12  ? 442 SER A N   1 
ATOM   3539  C CA  . SER A 1 442 ? -1.968  -55.733 -48.467 1.00 90.44  ? 442 SER A CA  1 
ATOM   3540  C C   . SER A 1 442 ? -2.885  -56.892 -48.861 1.00 93.09  ? 442 SER A C   1 
ATOM   3541  O O   . SER A 1 442 ? -4.097  -56.800 -48.693 1.00 97.27  ? 442 SER A O   1 
ATOM   3542  C CB  . SER A 1 442 ? -0.823  -56.170 -47.543 1.00 78.17  ? 442 SER A CB  1 
ATOM   3543  O OG  . SER A 1 442 ? -1.276  -56.717 -46.311 1.00 64.94  ? 442 SER A OG  1 
ATOM   3544  N N   . LYS A 1 443 ? -2.299  -57.948 -49.449 1.00 98.88  ? 443 LYS A N   1 
ATOM   3545  C CA  . LYS A 1 443 ? -3.014  -59.187 -49.724 1.00 95.51  ? 443 LYS A CA  1 
ATOM   3546  C C   . LYS A 1 443 ? -3.303  -59.917 -48.405 1.00 92.18  ? 443 LYS A C   1 
ATOM   3547  O O   . LYS A 1 443 ? -4.363  -60.540 -48.277 1.00 81.95  ? 443 LYS A O   1 
ATOM   3548  C CB  . LYS A 1 443 ? -2.224  -60.047 -50.723 1.00 93.05  ? 443 LYS A CB  1 
ATOM   3549  N N   . LEU A 1 444 ? -2.372  -59.808 -47.430 1.00 96.37  ? 444 LEU A N   1 
ATOM   3550  C CA  . LEU A 1 444 ? -2.462  -60.472 -46.124 1.00 100.23 ? 444 LEU A CA  1 
ATOM   3551  C C   . LEU A 1 444 ? -3.640  -59.898 -45.324 1.00 84.08  ? 444 LEU A C   1 
ATOM   3552  O O   . LEU A 1 444 ? -4.351  -60.646 -44.663 1.00 83.82  ? 444 LEU A O   1 
ATOM   3553  C CB  . LEU A 1 444 ? -1.167  -60.323 -45.298 1.00 101.36 ? 444 LEU A CB  1 
ATOM   3554  C CG  . LEU A 1 444 ? 0.143   -60.017 -46.041 1.00 124.20 ? 444 LEU A CG  1 
ATOM   3555  C CD1 . LEU A 1 444 ? 1.135   -59.291 -45.129 1.00 128.58 ? 444 LEU A CD1 1 
ATOM   3556  C CD2 . LEU A 1 444 ? 0.784   -61.281 -46.607 1.00 120.67 ? 444 LEU A CD2 1 
ATOM   3557  N N   . ALA A 1 445 ? -3.811  -58.563 -45.371 1.00 83.94  ? 445 ALA A N   1 
ATOM   3558  C CA  . ALA A 1 445 ? -4.914  -57.862 -44.725 1.00 86.93  ? 445 ALA A CA  1 
ATOM   3559  C C   . ALA A 1 445 ? -6.252  -58.294 -45.325 1.00 88.87  ? 445 ALA A C   1 
ATOM   3560  O O   . ALA A 1 445 ? -7.223  -58.479 -44.588 1.00 88.96  ? 445 ALA A O   1 
ATOM   3561  C CB  . ALA A 1 445 ? -4.726  -56.366 -44.862 1.00 88.11  ? 445 ALA A CB  1 
ATOM   3562  N N   . ALA A 1 446 ? -6.276  -58.447 -46.663 1.00 84.56  ? 446 ALA A N   1 
ATOM   3563  C CA  . ALA A 1 446 ? -7.455  -58.872 -47.408 1.00 87.39  ? 446 ALA A CA  1 
ATOM   3564  C C   . ALA A 1 446 ? -7.885  -60.297 -47.016 1.00 83.74  ? 446 ALA A C   1 
ATOM   3565  O O   . ALA A 1 446 ? -9.084  -60.564 -46.910 1.00 81.05  ? 446 ALA A O   1 
ATOM   3566  C CB  . ALA A 1 446 ? -7.198  -58.730 -48.898 1.00 80.38  ? 446 ALA A CB  1 
ATOM   3567  N N   . ALA A 1 447 ? -6.923  -61.200 -46.752 1.00 81.83  ? 447 ALA A N   1 
ATOM   3568  C CA  . ALA A 1 447 ? -7.232  -62.539 -46.250 1.00 89.05  ? 447 ALA A CA  1 
ATOM   3569  C C   . ALA A 1 447 ? -7.757  -62.506 -44.803 1.00 89.56  ? 447 ALA A C   1 
ATOM   3570  O O   . ALA A 1 447 ? -8.680  -63.255 -44.478 1.00 84.99  ? 447 ALA A O   1 
ATOM   3571  C CB  . ALA A 1 447 ? -6.017  -63.437 -46.380 1.00 85.92  ? 447 ALA A CB  1 
ATOM   3572  N N   . LEU A 1 448 ? -7.203  -61.628 -43.939 1.00 83.85  ? 448 LEU A N   1 
ATOM   3573  C CA  . LEU A 1 448 ? -7.475  -61.663 -42.502 1.00 85.54  ? 448 LEU A CA  1 
ATOM   3574  C C   . LEU A 1 448 ? -8.879  -61.119 -42.156 1.00 75.07  ? 448 LEU A C   1 
ATOM   3575  O O   . LEU A 1 448 ? -9.352  -60.172 -42.831 1.00 77.07  ? 448 LEU A O   1 
ATOM   3576  C CB  . LEU A 1 448 ? -6.370  -60.894 -41.766 1.00 67.95  ? 448 LEU A CB  1 
ATOM   3577  N N   . MET B 1 1   ? 19.215  -37.284 -7.651  1.00 75.98  ? 1   MET B N   1 
ATOM   3578  C CA  . MET B 1 1   ? 18.068  -38.136 -7.248  1.00 69.74  ? 1   MET B CA  1 
ATOM   3579  C C   . MET B 1 1   ? 18.065  -39.369 -8.152  1.00 63.78  ? 1   MET B C   1 
ATOM   3580  O O   . MET B 1 1   ? 18.218  -39.232 -9.359  1.00 56.82  ? 1   MET B O   1 
ATOM   3581  C CB  . MET B 1 1   ? 16.759  -37.339 -7.360  1.00 71.38  ? 1   MET B CB  1 
ATOM   3582  C CG  . MET B 1 1   ? 15.516  -38.126 -6.971  1.00 72.82  ? 1   MET B CG  1 
ATOM   3583  S SD  . MET B 1 1   ? 14.027  -37.411 -7.718  1.00 77.76  ? 1   MET B SD  1 
ATOM   3584  C CE  . MET B 1 1   ? 12.767  -38.294 -6.799  1.00 67.38  ? 1   MET B CE  1 
ATOM   3585  N N   . LYS B 1 2   ? 17.925  -40.566 -7.559  1.00 66.41  ? 2   LYS B N   1 
ATOM   3586  C CA  . LYS B 1 2   ? 18.095  -41.823 -8.271  1.00 73.93  ? 2   LYS B CA  1 
ATOM   3587  C C   . LYS B 1 2   ? 17.168  -41.886 -9.483  1.00 70.38  ? 2   LYS B C   1 
ATOM   3588  O O   . LYS B 1 2   ? 17.604  -42.153 -10.614 1.00 58.78  ? 2   LYS B O   1 
ATOM   3589  C CB  . LYS B 1 2   ? 17.793  -42.999 -7.339  1.00 100.72 ? 2   LYS B CB  1 
ATOM   3590  C CG  . LYS B 1 2   ? 18.853  -43.266 -6.277  1.00 127.64 ? 2   LYS B CG  1 
ATOM   3591  C CD  . LYS B 1 2   ? 20.130  -43.880 -6.832  1.00 144.41 ? 2   LYS B CD  1 
ATOM   3592  C CE  . LYS B 1 2   ? 21.055  -44.416 -5.758  1.00 144.92 ? 2   LYS B CE  1 
ATOM   3593  N NZ  . LYS B 1 2   ? 22.251  -45.069 -6.342  1.00 143.06 ? 2   LYS B NZ  1 
ATOM   3594  N N   . LEU B 1 3   ? 15.877  -41.657 -9.221  1.00 61.24  ? 3   LEU B N   1 
ATOM   3595  C CA  . LEU B 1 3   ? 14.866  -41.720 -10.260 1.00 52.04  ? 3   LEU B CA  1 
ATOM   3596  C C   . LEU B 1 3   ? 15.344  -40.973 -11.504 1.00 50.83  ? 3   LEU B C   1 
ATOM   3597  O O   . LEU B 1 3   ? 15.231  -41.477 -12.612 1.00 51.67  ? 3   LEU B O   1 
ATOM   3598  C CB  . LEU B 1 3   ? 13.561  -41.161 -9.694  1.00 50.42  ? 3   LEU B CB  1 
ATOM   3599  C CG  . LEU B 1 3   ? 12.391  -41.033 -10.676 1.00 54.41  ? 3   LEU B CG  1 
ATOM   3600  C CD1 . LEU B 1 3   ? 12.143  -42.320 -11.438 1.00 53.82  ? 3   LEU B CD1 1 
ATOM   3601  C CD2 . LEU B 1 3   ? 11.117  -40.627 -9.940  1.00 54.49  ? 3   LEU B CD2 1 
ATOM   3602  N N   . LYS B 1 4   ? 15.923  -39.795 -11.317 1.00 47.15  ? 4   LYS B N   1 
ATOM   3603  C CA  . LYS B 1 4   ? 16.260  -38.914 -12.421 1.00 57.81  ? 4   LYS B CA  1 
ATOM   3604  C C   . LYS B 1 4   ? 17.496  -39.421 -13.182 1.00 67.47  ? 4   LYS B C   1 
ATOM   3605  O O   . LYS B 1 4   ? 17.520  -39.315 -14.411 1.00 64.28  ? 4   LYS B O   1 
ATOM   3606  C CB  . LYS B 1 4   ? 16.416  -37.480 -11.892 1.00 51.74  ? 4   LYS B CB  1 
ATOM   3607  C CG  . LYS B 1 4   ? 16.859  -36.425 -12.898 1.00 57.68  ? 4   LYS B CG  1 
ATOM   3608  C CD  . LYS B 1 4   ? 16.740  -35.005 -12.343 1.00 67.05  ? 4   LYS B CD  1 
ATOM   3609  C CE  . LYS B 1 4   ? 17.486  -33.950 -13.133 1.00 66.99  ? 4   LYS B CE  1 
ATOM   3610  N NZ  . LYS B 1 4   ? 17.095  -33.944 -14.559 1.00 60.30  ? 4   LYS B NZ  1 
ATOM   3611  N N   . GLU B 1 5   ? 18.522  -39.943 -12.479 1.00 70.41  ? 5   GLU B N   1 
ATOM   3612  C CA  . GLU B 1 5   ? 19.735  -40.469 -13.118 1.00 76.12  ? 5   GLU B CA  1 
ATOM   3613  C C   . GLU B 1 5   ? 19.410  -41.653 -14.029 1.00 66.38  ? 5   GLU B C   1 
ATOM   3614  O O   . GLU B 1 5   ? 20.020  -41.818 -15.085 1.00 66.28  ? 5   GLU B O   1 
ATOM   3615  C CB  . GLU B 1 5   ? 20.741  -41.018 -12.102 1.00 79.25  ? 5   GLU B CB  1 
ATOM   3616  C CG  . GLU B 1 5   ? 21.287  -39.980 -11.141 1.00 85.76  ? 5   GLU B CG  1 
ATOM   3617  C CD  . GLU B 1 5   ? 21.701  -40.532 -9.782  1.00 86.98  ? 5   GLU B CD  1 
ATOM   3618  O OE1 . GLU B 1 5   ? 21.876  -39.713 -8.859  1.00 80.12  ? 5   GLU B OE1 1 
ATOM   3619  O OE2 . GLU B 1 5   ? 21.832  -41.776 -9.638  1.00 82.16  ? 5   GLU B OE2 1 
ATOM   3620  N N   . ARG B 1 6   ? 18.458  -42.468 -13.562 1.00 53.37  ? 6   ARG B N   1 
ATOM   3621  C CA  . ARG B 1 6   ? 18.020  -43.683 -14.219 1.00 58.47  ? 6   ARG B CA  1 
ATOM   3622  C C   . ARG B 1 6   ? 17.247  -43.341 -15.501 1.00 61.25  ? 6   ARG B C   1 
ATOM   3623  O O   . ARG B 1 6   ? 17.497  -43.887 -16.583 1.00 51.22  ? 6   ARG B O   1 
ATOM   3624  C CB  . ARG B 1 6   ? 17.160  -44.457 -13.214 1.00 61.79  ? 6   ARG B CB  1 
ATOM   3625  C CG  . ARG B 1 6   ? 16.987  -45.929 -13.534 1.00 75.36  ? 6   ARG B CG  1 
ATOM   3626  C CD  . ARG B 1 6   ? 18.274  -46.719 -13.342 1.00 76.89  ? 6   ARG B CD  1 
ATOM   3627  N NE  . ARG B 1 6   ? 18.220  -47.929 -14.148 1.00 80.26  ? 6   ARG B NE  1 
ATOM   3628  C CZ  . ARG B 1 6   ? 18.706  -48.061 -15.382 1.00 77.64  ? 6   ARG B CZ  1 
ATOM   3629  N NH1 . ARG B 1 6   ? 19.398  -47.088 -15.952 1.00 83.77  ? 6   ARG B NH1 1 
ATOM   3630  N NH2 . ARG B 1 6   ? 18.510  -49.190 -16.041 1.00 72.60  ? 6   ARG B NH2 1 
ATOM   3631  N N   . LEU B 1 7   ? 16.315  -42.395 -15.369 1.00 50.75  ? 7   LEU B N   1 
ATOM   3632  C CA  . LEU B 1 7   ? 15.499  -41.961 -16.480 1.00 54.44  ? 7   LEU B CA  1 
ATOM   3633  C C   . LEU B 1 7   ? 16.393  -41.350 -17.557 1.00 58.30  ? 7   LEU B C   1 
ATOM   3634  O O   . LEU B 1 7   ? 16.025  -41.378 -18.736 1.00 51.23  ? 7   LEU B O   1 
ATOM   3635  C CB  . LEU B 1 7   ? 14.471  -40.932 -15.982 1.00 55.84  ? 7   LEU B CB  1 
ATOM   3636  C CG  . LEU B 1 7   ? 13.227  -41.488 -15.288 1.00 52.53  ? 7   LEU B CG  1 
ATOM   3637  C CD1 . LEU B 1 7   ? 12.327  -40.332 -14.848 1.00 51.72  ? 7   LEU B CD1 1 
ATOM   3638  C CD2 . LEU B 1 7   ? 12.463  -42.418 -16.201 1.00 48.81  ? 7   LEU B CD2 1 
ATOM   3639  N N   . ALA B 1 8   ? 17.533  -40.779 -17.125 1.00 50.59  ? 8   ALA B N   1 
ATOM   3640  C CA  . ALA B 1 8   ? 18.473  -40.114 -18.010 1.00 52.71  ? 8   ALA B CA  1 
ATOM   3641  C C   . ALA B 1 8   ? 19.145  -41.139 -18.916 1.00 55.66  ? 8   ALA B C   1 
ATOM   3642  O O   . ALA B 1 8   ? 19.669  -40.746 -19.965 1.00 44.87  ? 8   ALA B O   1 
ATOM   3643  C CB  . ALA B 1 8   ? 19.517  -39.378 -17.209 1.00 54.03  ? 8   ALA B CB  1 
ATOM   3644  N N   . GLU B 1 9   ? 19.127  -42.415 -18.477 1.00 55.05  ? 9   GLU B N   1 
ATOM   3645  C CA  . GLU B 1 9   ? 19.635  -43.544 -19.245 1.00 61.75  ? 9   GLU B CA  1 
ATOM   3646  C C   . GLU B 1 9   ? 18.504  -44.236 -19.999 1.00 60.00  ? 9   GLU B C   1 
ATOM   3647  O O   . GLU B 1 9   ? 18.668  -44.508 -21.177 1.00 64.30  ? 9   GLU B O   1 
ATOM   3648  C CB  . GLU B 1 9   ? 20.345  -44.571 -18.356 1.00 73.05  ? 9   GLU B CB  1 
ATOM   3649  C CG  . GLU B 1 9   ? 21.697  -44.115 -17.822 1.00 80.40  ? 9   GLU B CG  1 
ATOM   3650  C CD  . GLU B 1 9   ? 22.380  -45.143 -16.925 1.00 103.40 ? 9   GLU B CD  1 
ATOM   3651  O OE1 . GLU B 1 9   ? 23.514  -45.589 -17.248 1.00 107.17 ? 9   GLU B OE1 1 
ATOM   3652  O OE2 . GLU B 1 9   ? 21.761  -45.525 -15.911 1.00 105.62 ? 9   GLU B OE2 1 
ATOM   3653  N N   . LEU B 1 10  ? 17.381  -44.544 -19.331 1.00 62.48  ? 10  LEU B N   1 
ATOM   3654  C CA  . LEU B 1 10  ? 16.279  -45.267 -19.967 1.00 63.43  ? 10  LEU B CA  1 
ATOM   3655  C C   . LEU B 1 10  ? 15.639  -44.479 -21.123 1.00 61.56  ? 10  LEU B C   1 
ATOM   3656  O O   . LEU B 1 10  ? 15.252  -45.063 -22.132 1.00 64.10  ? 10  LEU B O   1 
ATOM   3657  C CB  . LEU B 1 10  ? 15.213  -45.621 -18.925 1.00 51.07  ? 10  LEU B CB  1 
ATOM   3658  C CG  . LEU B 1 10  ? 15.569  -46.782 -18.001 1.00 57.46  ? 10  LEU B CG  1 
ATOM   3659  C CD1 . LEU B 1 10  ? 14.552  -46.936 -16.869 1.00 52.56  ? 10  LEU B CD1 1 
ATOM   3660  C CD2 . LEU B 1 10  ? 15.675  -48.092 -18.781 1.00 56.51  ? 10  LEU B CD2 1 
ATOM   3661  N N   . ILE B 1 11  ? 15.516  -43.160 -20.990 1.00 56.44  ? 11  ILE B N   1 
ATOM   3662  C CA  . ILE B 1 11  ? 14.625  -42.419 -21.863 1.00 55.71  ? 11  ILE B CA  1 
ATOM   3663  C C   . ILE B 1 11  ? 15.252  -42.233 -23.244 1.00 51.46  ? 11  ILE B C   1 
ATOM   3664  O O   . ILE B 1 11  ? 14.534  -42.339 -24.227 1.00 56.13  ? 11  ILE B O   1 
ATOM   3665  C CB  . ILE B 1 11  ? 14.133  -41.102 -21.213 1.00 52.85  ? 11  ILE B CB  1 
ATOM   3666  C CG1 . ILE B 1 11  ? 12.992  -41.376 -20.226 1.00 54.21  ? 11  ILE B CG1 1 
ATOM   3667  C CG2 . ILE B 1 11  ? 13.699  -40.076 -22.260 1.00 53.70  ? 11  ILE B CG2 1 
ATOM   3668  C CD1 . ILE B 1 11  ? 12.429  -40.122 -19.590 1.00 57.61  ? 11  ILE B CD1 1 
ATOM   3669  N N   . PRO B 1 12  ? 16.555  -41.909 -23.397 1.00 55.84  ? 12  PRO B N   1 
ATOM   3670  C CA  . PRO B 1 12  ? 17.163  -41.832 -24.733 1.00 57.21  ? 12  PRO B CA  1 
ATOM   3671  C C   . PRO B 1 12  ? 16.953  -43.105 -25.564 1.00 57.11  ? 12  PRO B C   1 
ATOM   3672  O O   . PRO B 1 12  ? 16.777  -43.044 -26.792 1.00 48.34  ? 12  PRO B O   1 
ATOM   3673  C CB  . PRO B 1 12  ? 18.664  -41.637 -24.436 1.00 65.82  ? 12  PRO B CB  1 
ATOM   3674  C CG  . PRO B 1 12  ? 18.708  -41.022 -23.035 1.00 66.64  ? 12  PRO B CG  1 
ATOM   3675  C CD  . PRO B 1 12  ? 17.491  -41.565 -22.314 1.00 57.69  ? 12  PRO B CD  1 
ATOM   3676  N N   . GLN B 1 13  ? 16.963  -44.249 -24.854 1.00 53.85  ? 13  GLN B N   1 
ATOM   3677  C CA  . GLN B 1 13  ? 16.828  -45.570 -25.446 1.00 58.61  ? 13  GLN B CA  1 
ATOM   3678  C C   . GLN B 1 13  ? 15.404  -45.774 -25.934 1.00 55.51  ? 13  GLN B C   1 
ATOM   3679  O O   . GLN B 1 13  ? 15.191  -46.205 -27.068 1.00 55.66  ? 13  GLN B O   1 
ATOM   3680  C CB  . GLN B 1 13  ? 17.142  -46.690 -24.442 1.00 66.81  ? 13  GLN B CB  1 
ATOM   3681  C CG  . GLN B 1 13  ? 18.597  -46.755 -23.971 1.00 67.69  ? 13  GLN B CG  1 
ATOM   3682  C CD  . GLN B 1 13  ? 18.777  -47.832 -22.917 1.00 73.58  ? 13  GLN B CD  1 
ATOM   3683  O OE1 . GLN B 1 13  ? 18.629  -49.025 -23.184 1.00 84.83  ? 13  GLN B OE1 1 
ATOM   3684  N NE2 . GLN B 1 13  ? 19.066  -47.428 -21.689 1.00 68.61  ? 13  GLN B NE2 1 
ATOM   3685  N N   . TRP B 1 14  ? 14.443  -45.529 -25.036 1.00 56.72  ? 14  TRP B N   1 
ATOM   3686  C CA  . TRP B 1 14  ? 13.043  -45.655 -25.395 1.00 57.14  ? 14  TRP B CA  1 
ATOM   3687  C C   . TRP B 1 14  ? 12.753  -44.730 -26.572 1.00 50.67  ? 14  TRP B C   1 
ATOM   3688  O O   . TRP B 1 14  ? 12.132  -45.125 -27.542 1.00 53.49  ? 14  TRP B O   1 
ATOM   3689  C CB  . TRP B 1 14  ? 12.140  -45.351 -24.204 1.00 50.34  ? 14  TRP B CB  1 
ATOM   3690  C CG  . TRP B 1 14  ? 12.155  -46.380 -23.118 1.00 60.49  ? 14  TRP B CG  1 
ATOM   3691  C CD1 . TRP B 1 14  ? 12.442  -47.707 -23.234 1.00 66.86  ? 14  TRP B CD1 1 
ATOM   3692  C CD2 . TRP B 1 14  ? 11.856  -46.160 -21.729 1.00 58.69  ? 14  TRP B CD2 1 
ATOM   3693  N NE1 . TRP B 1 14  ? 12.331  -48.327 -22.019 1.00 69.51  ? 14  TRP B NE1 1 
ATOM   3694  C CE2 . TRP B 1 14  ? 11.982  -47.407 -21.074 1.00 57.51  ? 14  TRP B CE2 1 
ATOM   3695  C CE3 . TRP B 1 14  ? 11.507  -45.031 -20.977 1.00 49.44  ? 14  TRP B CE3 1 
ATOM   3696  C CZ2 . TRP B 1 14  ? 11.758  -47.565 -19.710 1.00 50.00  ? 14  TRP B CZ2 1 
ATOM   3697  C CZ3 . TRP B 1 14  ? 11.290  -45.186 -19.622 1.00 50.35  ? 14  TRP B CZ3 1 
ATOM   3698  C CH2 . TRP B 1 14  ? 11.425  -46.433 -19.000 1.00 53.71  ? 14  TRP B CH2 1 
ATOM   3699  N N   . ARG B 1 15  ? 13.203  -43.487 -26.467 1.00 42.86  ? 15  ARG B N   1 
ATOM   3700  C CA  . ARG B 1 15  ? 13.020  -42.553 -27.546 1.00 52.54  ? 15  ARG B CA  1 
ATOM   3701  C C   . ARG B 1 15  ? 13.441  -43.235 -28.854 1.00 52.50  ? 15  ARG B C   1 
ATOM   3702  O O   . ARG B 1 15  ? 12.700  -43.157 -29.821 1.00 44.29  ? 15  ARG B O   1 
ATOM   3703  C CB  . ARG B 1 15  ? 13.820  -41.276 -27.255 1.00 59.83  ? 15  ARG B CB  1 
ATOM   3704  C CG  . ARG B 1 15  ? 13.781  -40.252 -28.378 1.00 60.10  ? 15  ARG B CG  1 
ATOM   3705  C CD  . ARG B 1 15  ? 14.677  -39.057 -28.128 1.00 71.40  ? 15  ARG B CD  1 
ATOM   3706  N NE  . ARG B 1 15  ? 14.568  -38.213 -29.318 1.00 91.26  ? 15  ARG B NE  1 
ATOM   3707  C CZ  . ARG B 1 15  ? 15.565  -37.558 -29.913 1.00 103.27 ? 15  ARG B CZ  1 
ATOM   3708  N NH1 . ARG B 1 15  ? 16.743  -37.428 -29.322 1.00 101.89 ? 15  ARG B NH1 1 
ATOM   3709  N NH2 . ARG B 1 15  ? 15.355  -36.978 -31.084 1.00 110.12 ? 15  ARG B NH2 1 
ATOM   3710  N N   . ALA B 1 16  ? 14.628  -43.873 -28.884 1.00 56.27  ? 16  ALA B N   1 
ATOM   3711  C CA  . ALA B 1 16  ? 15.164  -44.440 -30.122 1.00 58.92  ? 16  ALA B CA  1 
ATOM   3712  C C   . ALA B 1 16  ? 14.333  -45.655 -30.529 1.00 53.54  ? 16  ALA B C   1 
ATOM   3713  O O   . ALA B 1 16  ? 14.069  -45.830 -31.714 1.00 55.45  ? 16  ALA B O   1 
ATOM   3714  C CB  . ALA B 1 16  ? 16.645  -44.780 -30.033 1.00 48.29  ? 16  ALA B CB  1 
ATOM   3715  N N   . GLU B 1 17  ? 13.881  -46.459 -29.558 1.00 45.46  ? 17  GLU B N   1 
ATOM   3716  C CA  . GLU B 1 17  ? 13.065  -47.610 -29.890 1.00 49.03  ? 17  GLU B CA  1 
ATOM   3717  C C   . GLU B 1 17  ? 11.768  -47.158 -30.568 1.00 56.76  ? 17  GLU B C   1 
ATOM   3718  O O   . GLU B 1 17  ? 11.355  -47.737 -31.572 1.00 53.38  ? 17  GLU B O   1 
ATOM   3719  C CB  . GLU B 1 17  ? 12.763  -48.476 -28.666 1.00 52.48  ? 17  GLU B CB  1 
ATOM   3720  C CG  . GLU B 1 17  ? 11.838  -49.658 -28.971 1.00 65.84  ? 17  GLU B CG  1 
ATOM   3721  C CD  . GLU B 1 17  ? 12.360  -50.709 -29.957 1.00 79.36  ? 17  GLU B CD  1 
ATOM   3722  O OE1 . GLU B 1 17  ? 13.553  -51.086 -29.866 1.00 89.85  ? 17  GLU B OE1 1 
ATOM   3723  O OE2 . GLU B 1 17  ? 11.575  -51.171 -30.818 1.00 78.95  ? 17  GLU B OE2 1 
ATOM   3724  N N   . VAL B 1 18  ? 11.123  -46.123 -30.013 1.00 51.76  ? 18  VAL B N   1 
ATOM   3725  C CA  . VAL B 1 18  ? 9.859   -45.654 -30.545 1.00 51.34  ? 18  VAL B CA  1 
ATOM   3726  C C   . VAL B 1 18  ? 10.066  -45.119 -31.963 1.00 48.28  ? 18  VAL B C   1 
ATOM   3727  O O   . VAL B 1 18  ? 9.226   -45.344 -32.819 1.00 46.45  ? 18  VAL B O   1 
ATOM   3728  C CB  . VAL B 1 18  ? 9.198   -44.620 -29.610 1.00 43.53  ? 18  VAL B CB  1 
ATOM   3729  C CG1 . VAL B 1 18  ? 8.106   -43.830 -30.305 1.00 39.92  ? 18  VAL B CG1 1 
ATOM   3730  C CG2 . VAL B 1 18  ? 8.668   -45.285 -28.356 1.00 45.59  ? 18  VAL B CG2 1 
ATOM   3731  N N   . ALA B 1 19  ? 11.163  -44.397 -32.218 1.00 48.31  ? 19  ALA B N   1 
ATOM   3732  C CA  . ALA B 1 19  ? 11.372  -43.842 -33.547 1.00 53.32  ? 19  ALA B CA  1 
ATOM   3733  C C   . ALA B 1 19  ? 11.422  -44.987 -34.578 1.00 53.75  ? 19  ALA B C   1 
ATOM   3734  O O   . ALA B 1 19  ? 10.842  -44.877 -35.652 1.00 47.92  ? 19  ALA B O   1 
ATOM   3735  C CB  . ALA B 1 19  ? 12.606  -42.965 -33.563 1.00 49.70  ? 19  ALA B CB  1 
ATOM   3736  N N   . GLU B 1 20  ? 12.056  -46.108 -34.210 1.00 56.12  ? 20  GLU B N   1 
ATOM   3737  C CA  . GLU B 1 20  ? 12.197  -47.275 -35.069 1.00 55.82  ? 20  GLU B CA  1 
ATOM   3738  C C   . GLU B 1 20  ? 10.862  -47.980 -35.277 1.00 55.01  ? 20  GLU B C   1 
ATOM   3739  O O   . GLU B 1 20  ? 10.467  -48.265 -36.403 1.00 50.96  ? 20  GLU B O   1 
ATOM   3740  C CB  . GLU B 1 20  ? 13.161  -48.268 -34.443 1.00 56.96  ? 20  GLU B CB  1 
ATOM   3741  C CG  . GLU B 1 20  ? 14.584  -47.760 -34.426 1.00 64.27  ? 20  GLU B CG  1 
ATOM   3742  C CD  . GLU B 1 20  ? 15.585  -48.852 -34.094 1.00 68.93  ? 20  GLU B CD  1 
ATOM   3743  O OE1 . GLU B 1 20  ? 15.132  -49.974 -33.722 1.00 70.02  ? 20  GLU B OE1 1 
ATOM   3744  O OE2 . GLU B 1 20  ? 16.804  -48.594 -34.240 1.00 73.47  ? 20  GLU B OE2 1 
ATOM   3745  N N   . ILE B 1 21  ? 10.163  -48.269 -34.184 1.00 51.92  ? 21  ILE B N   1 
ATOM   3746  C CA  . ILE B 1 21  ? 8.847   -48.876 -34.290 1.00 52.78  ? 21  ILE B CA  1 
ATOM   3747  C C   . ILE B 1 21  ? 7.947   -48.123 -35.271 1.00 48.07  ? 21  ILE B C   1 
ATOM   3748  O O   . ILE B 1 21  ? 7.202   -48.736 -36.022 1.00 48.87  ? 21  ILE B O   1 
ATOM   3749  C CB  . ILE B 1 21  ? 8.197   -48.950 -32.902 1.00 50.02  ? 21  ILE B CB  1 
ATOM   3750  C CG1 . ILE B 1 21  ? 8.879   -50.019 -32.054 1.00 51.39  ? 21  ILE B CG1 1 
ATOM   3751  C CG2 . ILE B 1 21  ? 6.699   -49.165 -33.044 1.00 49.02  ? 21  ILE B CG2 1 
ATOM   3752  C CD1 . ILE B 1 21  ? 8.439   -50.031 -30.609 1.00 60.07  ? 21  ILE B CD1 1 
ATOM   3753  N N   . ARG B 1 22  ? 7.951   -46.793 -35.175 1.00 46.47  ? 22  ARG B N   1 
ATOM   3754  C CA  . ARG B 1 22  ? 7.065   -45.932 -35.932 1.00 49.43  ? 22  ARG B CA  1 
ATOM   3755  C C   . ARG B 1 22  ? 7.435   -46.042 -37.413 1.00 50.49  ? 22  ARG B C   1 
ATOM   3756  O O   . ARG B 1 22  ? 6.611   -45.917 -38.314 1.00 48.98  ? 22  ARG B O   1 
ATOM   3757  C CB  . ARG B 1 22  ? 7.208   -44.478 -35.433 1.00 54.14  ? 22  ARG B CB  1 
ATOM   3758  C CG  . ARG B 1 22  ? 6.543   -44.164 -34.092 1.00 63.31  ? 22  ARG B CG  1 
ATOM   3759  C CD  . ARG B 1 22  ? 6.549   -42.683 -33.696 1.00 61.87  ? 22  ARG B CD  1 
ATOM   3760  N NE  . ARG B 1 22  ? 5.776   -41.873 -34.626 1.00 60.98  ? 22  ARG B NE  1 
ATOM   3761  C CZ  . ARG B 1 22  ? 5.903   -40.559 -34.797 1.00 55.65  ? 22  ARG B CZ  1 
ATOM   3762  N NH1 . ARG B 1 22  ? 6.798   -39.885 -34.104 1.00 50.14  ? 22  ARG B NH1 1 
ATOM   3763  N NH2 . ARG B 1 22  ? 5.119   -39.919 -35.653 1.00 56.86  ? 22  ARG B NH2 1 
ATOM   3764  N N   . LYS B 1 23  ? 8.729   -46.204 -37.634 1.00 48.57  ? 23  LYS B N   1 
ATOM   3765  C CA  . LYS B 1 23  ? 9.301   -46.285 -38.957 1.00 56.03  ? 23  LYS B CA  1 
ATOM   3766  C C   . LYS B 1 23  ? 8.961   -47.661 -39.525 1.00 57.23  ? 23  LYS B C   1 
ATOM   3767  O O   . LYS B 1 23  ? 8.359   -47.754 -40.595 1.00 50.52  ? 23  LYS B O   1 
ATOM   3768  C CB  . LYS B 1 23  ? 10.801  -46.004 -38.835 1.00 61.17  ? 23  LYS B CB  1 
ATOM   3769  C CG  . LYS B 1 23  ? 11.493  -45.640 -40.130 1.00 79.26  ? 23  LYS B CG  1 
ATOM   3770  C CD  . LYS B 1 23  ? 11.034  -44.343 -40.731 1.00 90.17  ? 23  LYS B CD  1 
ATOM   3771  C CE  . LYS B 1 23  ? 11.833  -44.003 -41.968 1.00 95.28  ? 23  LYS B CE  1 
ATOM   3772  N NZ  . LYS B 1 23  ? 11.664  -42.586 -42.348 1.00 96.69  ? 23  LYS B NZ  1 
ATOM   3773  N N   . LYS B 1 24  ? 9.233   -48.719 -38.745 1.00 53.18  ? 24  LYS B N   1 
ATOM   3774  C CA  . LYS B 1 24  ? 9.241   -50.058 -39.302 1.00 47.25  ? 24  LYS B CA  1 
ATOM   3775  C C   . LYS B 1 24  ? 7.906   -50.775 -39.158 1.00 47.33  ? 24  LYS B C   1 
ATOM   3776  O O   . LYS B 1 24  ? 7.647   -51.646 -39.987 1.00 44.34  ? 24  LYS B O   1 
ATOM   3777  C CB  . LYS B 1 24  ? 10.422  -50.859 -38.774 1.00 46.91  ? 24  LYS B CB  1 
ATOM   3778  C CG  . LYS B 1 24  ? 10.273  -51.524 -37.422 1.00 52.37  ? 24  LYS B CG  1 
ATOM   3779  C CD  . LYS B 1 24  ? 11.593  -52.175 -37.035 1.00 55.70  ? 24  LYS B CD  1 
ATOM   3780  C CE  . LYS B 1 24  ? 11.513  -53.012 -35.781 1.00 64.54  ? 24  LYS B CE  1 
ATOM   3781  N NZ  . LYS B 1 24  ? 12.858  -53.431 -35.340 1.00 62.40  ? 24  LYS B NZ  1 
ATOM   3782  N N   . TYR B 1 25  ? 7.040   -50.361 -38.214 1.00 47.33  ? 25  TYR B N   1 
ATOM   3783  C CA  . TYR B 1 25  ? 5.751   -51.013 -37.994 1.00 44.56  ? 25  TYR B CA  1 
ATOM   3784  C C   . TYR B 1 25  ? 4.561   -50.067 -38.174 1.00 44.14  ? 25  TYR B C   1 
ATOM   3785  O O   . TYR B 1 25  ? 3.437   -50.424 -37.836 1.00 47.17  ? 25  TYR B O   1 
ATOM   3786  C CB  . TYR B 1 25  ? 5.675   -51.607 -36.572 1.00 50.26  ? 25  TYR B CB  1 
ATOM   3787  C CG  . TYR B 1 25  ? 6.675   -52.690 -36.226 1.00 52.21  ? 25  TYR B CG  1 
ATOM   3788  C CD1 . TYR B 1 25  ? 7.032   -53.687 -37.140 1.00 53.92  ? 25  TYR B CD1 1 
ATOM   3789  C CD2 . TYR B 1 25  ? 7.218   -52.774 -34.958 1.00 51.63  ? 25  TYR B CD2 1 
ATOM   3790  C CE1 . TYR B 1 25  ? 7.921   -54.703 -36.816 1.00 49.46  ? 25  TYR B CE1 1 
ATOM   3791  C CE2 . TYR B 1 25  ? 8.135   -53.766 -34.624 1.00 57.98  ? 25  TYR B CE2 1 
ATOM   3792  C CZ  . TYR B 1 25  ? 8.472   -54.745 -35.547 1.00 59.79  ? 25  TYR B CZ  1 
ATOM   3793  O OH  . TYR B 1 25  ? 9.348   -55.742 -35.201 1.00 56.32  ? 25  TYR B OH  1 
ATOM   3794  N N   . GLY B 1 26  ? 4.788   -48.857 -38.684 1.00 48.31  ? 26  GLY B N   1 
ATOM   3795  C CA  . GLY B 1 26  ? 3.771   -47.814 -38.712 1.00 45.12  ? 26  GLY B CA  1 
ATOM   3796  C C   . GLY B 1 26  ? 2.556   -48.133 -39.576 1.00 48.28  ? 26  GLY B C   1 
ATOM   3797  O O   . GLY B 1 26  ? 1.441   -47.736 -39.246 1.00 44.91  ? 26  GLY B O   1 
ATOM   3798  N N   . ASN B 1 27  ? 2.777   -48.862 -40.678 1.00 51.69  ? 27  ASN B N   1 
ATOM   3799  C CA  . ASN B 1 27  ? 1.693   -49.230 -41.572 1.00 55.48  ? 27  ASN B CA  1 
ATOM   3800  C C   . ASN B 1 27  ? 1.058   -50.557 -41.163 1.00 51.08  ? 27  ASN B C   1 
ATOM   3801  O O   . ASN B 1 27  ? 0.135   -51.031 -41.825 1.00 55.68  ? 27  ASN B O   1 
ATOM   3802  C CB  . ASN B 1 27  ? 2.095   -49.167 -43.058 1.00 58.82  ? 27  ASN B CB  1 
ATOM   3803  C CG  . ASN B 1 27  ? 3.345   -49.919 -43.471 1.00 60.75  ? 27  ASN B CG  1 
ATOM   3804  O OD1 . ASN B 1 27  ? 3.697   -49.901 -44.648 1.00 72.95  ? 27  ASN B OD1 1 
ATOM   3805  N ND2 . ASN B 1 27  ? 4.010   -50.602 -42.553 1.00 61.66  ? 27  ASN B ND2 1 
ATOM   3806  N N   . ARG B 1 28  ? 1.474   -51.136 -40.038 1.00 49.68  ? 28  ARG B N   1 
ATOM   3807  C CA  . ARG B 1 28  ? 0.844   -52.367 -39.590 1.00 47.15  ? 28  ARG B CA  1 
ATOM   3808  C C   . ARG B 1 28  ? -0.582  -52.108 -39.121 1.00 50.38  ? 28  ARG B C   1 
ATOM   3809  O O   . ARG B 1 28  ? -0.821  -51.230 -38.295 1.00 51.33  ? 28  ARG B O   1 
ATOM   3810  C CB  . ARG B 1 28  ? 1.666   -53.000 -38.477 1.00 48.09  ? 28  ARG B CB  1 
ATOM   3811  C CG  . ARG B 1 28  ? 3.059   -53.407 -38.925 1.00 51.02  ? 28  ARG B CG  1 
ATOM   3812  C CD  . ARG B 1 28  ? 3.029   -54.492 -39.991 1.00 53.19  ? 28  ARG B CD  1 
ATOM   3813  N NE  . ARG B 1 28  ? 4.370   -54.851 -40.439 1.00 51.76  ? 28  ARG B NE  1 
ATOM   3814  C CZ  . ARG B 1 28  ? 4.844   -56.093 -40.533 1.00 55.82  ? 28  ARG B CZ  1 
ATOM   3815  N NH1 . ARG B 1 28  ? 6.142   -56.247 -40.735 1.00 51.90  ? 28  ARG B NH1 1 
ATOM   3816  N NH2 . ARG B 1 28  ? 4.049   -57.155 -40.375 1.00 46.48  ? 28  ARG B NH2 1 
ATOM   3817  N N   . LYS B 1 29  ? -1.524  -52.899 -39.637 1.00 49.93  ? 29  LYS B N   1 
ATOM   3818  C CA  . LYS B 1 29  ? -2.937  -52.731 -39.332 1.00 54.20  ? 29  LYS B CA  1 
ATOM   3819  C C   . LYS B 1 29  ? -3.295  -53.476 -38.046 1.00 54.57  ? 29  LYS B C   1 
ATOM   3820  O O   . LYS B 1 29  ? -2.971  -54.647 -37.884 1.00 60.78  ? 29  LYS B O   1 
ATOM   3821  C CB  . LYS B 1 29  ? -3.829  -53.202 -40.495 1.00 53.84  ? 29  LYS B CB  1 
ATOM   3822  C CG  . LYS B 1 29  ? -5.305  -53.346 -40.149 1.00 58.93  ? 29  LYS B CG  1 
ATOM   3823  C CD  . LYS B 1 29  ? -6.151  -53.982 -41.223 1.00 67.73  ? 29  LYS B CD  1 
ATOM   3824  C CE  . LYS B 1 29  ? -7.560  -54.247 -40.733 1.00 70.09  ? 29  LYS B CE  1 
ATOM   3825  N NZ  . LYS B 1 29  ? -8.468  -54.659 -41.826 1.00 75.18  ? 29  LYS B NZ  1 
ATOM   3826  N N   . THR B 1 30  ? -4.051  -52.789 -37.180 1.00 55.91  ? 30  THR B N   1 
ATOM   3827  C CA  . THR B 1 30  ? -4.487  -53.316 -35.894 1.00 51.27  ? 30  THR B CA  1 
ATOM   3828  C C   . THR B 1 30  ? -5.986  -53.593 -35.936 1.00 48.67  ? 30  THR B C   1 
ATOM   3829  O O   . THR B 1 30  ? -6.455  -54.499 -35.253 1.00 48.37  ? 30  THR B O   1 
ATOM   3830  C CB  . THR B 1 30  ? -4.131  -52.356 -34.735 1.00 47.75  ? 30  THR B CB  1 
ATOM   3831  O OG1 . THR B 1 30  ? -4.642  -51.057 -35.033 1.00 58.32  ? 30  THR B OG1 1 
ATOM   3832  C CG2 . THR B 1 30  ? -2.647  -52.223 -34.501 1.00 46.62  ? 30  THR B CG2 1 
ATOM   3833  N N   . MET B 1 31  ? -6.745  -52.799 -36.711 1.00 48.40  ? 31  MET B N   1 
ATOM   3834  C CA  . MET B 1 31  ? -8.180  -52.994 -36.793 1.00 44.58  ? 31  MET B CA  1 
ATOM   3835  C C   . MET B 1 31  ? -8.779  -52.087 -37.858 1.00 51.83  ? 31  MET B C   1 
ATOM   3836  O O   . MET B 1 31  ? -8.087  -51.235 -38.429 1.00 54.43  ? 31  MET B O   1 
ATOM   3837  C CB  . MET B 1 31  ? -8.881  -52.709 -35.460 1.00 46.29  ? 31  MET B CB  1 
ATOM   3838  C CG  . MET B 1 31  ? -8.605  -51.324 -34.919 1.00 52.05  ? 31  MET B CG  1 
ATOM   3839  S SD  . MET B 1 31  ? -9.159  -51.111 -33.179 1.00 47.35  ? 31  MET B SD  1 
ATOM   3840  C CE  . MET B 1 31  ? -10.933 -51.221 -33.363 1.00 42.83  ? 31  MET B CE  1 
ATOM   3841  N N   . ASP B 1 32  ? -10.077 -52.325 -38.120 1.00 50.67  ? 32  ASP B N   1 
ATOM   3842  C CA  . ASP B 1 32  ? -10.874 -51.463 -38.968 1.00 50.90  ? 32  ASP B CA  1 
ATOM   3843  C C   . ASP B 1 32  ? -11.376 -50.289 -38.140 1.00 54.46  ? 32  ASP B C   1 
ATOM   3844  O O   . ASP B 1 32  ? -11.847 -50.466 -37.022 1.00 65.40  ? 32  ASP B O   1 
ATOM   3845  C CB  . ASP B 1 32  ? -12.077 -52.216 -39.559 1.00 59.12  ? 32  ASP B CB  1 
ATOM   3846  C CG  . ASP B 1 32  ? -11.714 -53.335 -40.534 1.00 57.25  ? 32  ASP B CG  1 
ATOM   3847  O OD1 . ASP B 1 32  ? -10.652 -53.236 -41.186 1.00 48.11  ? 32  ASP B OD1 1 
ATOM   3848  O OD2 . ASP B 1 32  ? -12.487 -54.309 -40.614 1.00 62.14  ? 32  ASP B OD2 1 
ATOM   3849  N N   . CYS B 1 33  ? -11.302 -49.102 -38.736 1.00 57.85  ? 33  CYS B N   1 
ATOM   3850  C CA  . CYS B 1 33  ? -12.011 -47.923 -38.280 1.00 49.61  ? 33  CYS B CA  1 
ATOM   3851  C C   . CYS B 1 33  ? -13.363 -47.869 -38.996 1.00 54.82  ? 33  CYS B C   1 
ATOM   3852  O O   . CYS B 1 33  ? -13.409 -48.013 -40.216 1.00 59.97  ? 33  CYS B O   1 
ATOM   3853  C CB  . CYS B 1 33  ? -11.156 -46.695 -38.584 1.00 49.92  ? 33  CYS B CB  1 
ATOM   3854  S SG  . CYS B 1 33  ? -11.741 -45.168 -37.804 1.00 55.47  ? 33  CYS B SG  1 
ATOM   3855  N N   . THR B 1 34  ? -14.434 -47.558 -38.253 1.00 49.52  ? 34  THR B N   1 
ATOM   3856  C CA  . THR B 1 34  ? -15.803 -47.700 -38.701 1.00 48.37  ? 34  THR B CA  1 
ATOM   3857  C C   . THR B 1 34  ? -16.593 -46.408 -38.479 1.00 51.65  ? 34  THR B C   1 
ATOM   3858  O O   . THR B 1 34  ? -16.219 -45.558 -37.681 1.00 60.41  ? 34  THR B O   1 
ATOM   3859  C CB  . THR B 1 34  ? -16.504 -48.863 -37.978 1.00 57.18  ? 34  THR B CB  1 
ATOM   3860  O OG1 . THR B 1 34  ? -16.708 -48.492 -36.613 1.00 55.22  ? 34  THR B OG1 1 
ATOM   3861  C CG2 . THR B 1 34  ? -15.727 -50.161 -38.035 1.00 55.93  ? 34  THR B CG2 1 
ATOM   3862  N N   . ILE B 1 35  ? -17.737 -46.288 -39.160 1.00 50.47  ? 35  ILE B N   1 
ATOM   3863  C CA  . ILE B 1 35  ? -18.706 -45.237 -38.877 1.00 54.70  ? 35  ILE B CA  1 
ATOM   3864  C C   . ILE B 1 35  ? -19.086 -45.288 -37.394 1.00 49.33  ? 35  ILE B C   1 
ATOM   3865  O O   . ILE B 1 35  ? -19.290 -44.256 -36.776 1.00 49.68  ? 35  ILE B O   1 
ATOM   3866  C CB  . ILE B 1 35  ? -19.939 -45.338 -39.815 1.00 48.39  ? 35  ILE B CB  1 
ATOM   3867  C CG1 . ILE B 1 35  ? -19.578 -45.100 -41.279 1.00 51.73  ? 35  ILE B CG1 1 
ATOM   3868  C CG2 . ILE B 1 35  ? -21.061 -44.397 -39.416 1.00 47.20  ? 35  ILE B CG2 1 
ATOM   3869  C CD1 . ILE B 1 35  ? -19.215 -43.673 -41.566 1.00 56.21  ? 35  ILE B CD1 1 
ATOM   3870  N N   . GLY B 1 36  ? -19.197 -46.486 -36.835 1.00 54.34  ? 36  GLY B N   1 
ATOM   3871  C CA  . GLY B 1 36  ? -19.672 -46.667 -35.474 1.00 51.87  ? 36  GLY B CA  1 
ATOM   3872  C C   . GLY B 1 36  ? -18.665 -46.138 -34.459 1.00 56.12  ? 36  GLY B C   1 
ATOM   3873  O O   . GLY B 1 36  ? -19.070 -45.727 -33.373 1.00 52.70  ? 36  GLY B O   1 
ATOM   3874  N N   . HIS B 1 37  ? -17.369 -46.185 -34.815 1.00 51.11  ? 37  HIS B N   1 
ATOM   3875  C CA  . HIS B 1 37  ? -16.320 -45.592 -34.001 1.00 49.20  ? 37  HIS B CA  1 
ATOM   3876  C C   . HIS B 1 37  ? -16.503 -44.065 -33.921 1.00 57.69  ? 37  HIS B C   1 
ATOM   3877  O O   . HIS B 1 37  ? -16.512 -43.474 -32.838 1.00 50.32  ? 37  HIS B O   1 
ATOM   3878  C CB  . HIS B 1 37  ? -14.939 -45.926 -34.575 1.00 48.92  ? 37  HIS B CB  1 
ATOM   3879  C CG  . HIS B 1 37  ? -14.511 -47.336 -34.370 1.00 58.76  ? 37  HIS B CG  1 
ATOM   3880  N ND1 . HIS B 1 37  ? -14.398 -47.861 -33.097 1.00 69.41  ? 37  HIS B ND1 1 
ATOM   3881  C CD2 . HIS B 1 37  ? -14.175 -48.325 -35.194 1.00 57.06  ? 37  HIS B CD2 1 
ATOM   3882  C CE1 . HIS B 1 37  ? -14.013 -49.121 -33.169 1.00 57.51  ? 37  HIS B CE1 1 
ATOM   3883  N NE2 . HIS B 1 37  ? -13.886 -49.433 -34.432 1.00 57.02  ? 37  HIS B NE2 1 
ATOM   3884  N N   . ALA B 1 38  ? -16.696 -43.424 -35.082 1.00 49.01  ? 38  ALA B N   1 
ATOM   3885  C CA  . ALA B 1 38  ? -16.780 -41.975 -35.163 1.00 45.92  ? 38  ALA B CA  1 
ATOM   3886  C C   . ALA B 1 38  ? -17.965 -41.433 -34.380 1.00 52.27  ? 38  ALA B C   1 
ATOM   3887  O O   . ALA B 1 38  ? -17.844 -40.358 -33.796 1.00 52.12  ? 38  ALA B O   1 
ATOM   3888  C CB  . ALA B 1 38  ? -16.836 -41.542 -36.593 1.00 47.47  ? 38  ALA B CB  1 
ATOM   3889  N N   . TYR B 1 39  ? -19.101 -42.149 -34.403 1.00 49.27  ? 39  TYR B N   1 
ATOM   3890  C CA  . TYR B 1 39  ? -20.311 -41.702 -33.735 1.00 43.71  ? 39  TYR B CA  1 
ATOM   3891  C C   . TYR B 1 39  ? -20.422 -42.337 -32.364 1.00 45.51  ? 39  TYR B C   1 
ATOM   3892  O O   . TYR B 1 39  ? -21.406 -42.104 -31.681 1.00 42.21  ? 39  TYR B O   1 
ATOM   3893  C CB  . TYR B 1 39  ? -21.580 -42.069 -34.524 1.00 42.65  ? 39  TYR B CB  1 
ATOM   3894  C CG  . TYR B 1 39  ? -21.837 -41.208 -35.739 1.00 47.70  ? 39  TYR B CG  1 
ATOM   3895  C CD1 . TYR B 1 39  ? -21.280 -41.498 -36.973 1.00 46.49  ? 39  TYR B CD1 1 
ATOM   3896  C CD2 . TYR B 1 39  ? -22.600 -40.066 -35.640 1.00 53.57  ? 39  TYR B CD2 1 
ATOM   3897  C CE1 . TYR B 1 39  ? -21.482 -40.679 -38.070 1.00 49.13  ? 39  TYR B CE1 1 
ATOM   3898  C CE2 . TYR B 1 39  ? -22.816 -39.238 -36.728 1.00 58.04  ? 39  TYR B CE2 1 
ATOM   3899  C CZ  . TYR B 1 39  ? -22.263 -39.544 -37.952 1.00 55.80  ? 39  TYR B CZ  1 
ATOM   3900  O OH  . TYR B 1 39  ? -22.503 -38.686 -39.006 1.00 60.79  ? 39  TYR B OH  1 
ATOM   3901  N N   . GLY B 1 40  ? -19.422 -43.144 -31.978 1.00 48.13  ? 40  GLY B N   1 
ATOM   3902  C CA  . GLY B 1 40  ? -19.573 -44.028 -30.837 1.00 51.99  ? 40  GLY B CA  1 
ATOM   3903  C C   . GLY B 1 40  ? -18.462 -43.863 -29.813 1.00 49.30  ? 40  GLY B C   1 
ATOM   3904  O O   . GLY B 1 40  ? -18.169 -44.780 -29.049 1.00 53.80  ? 40  GLY B O   1 
ATOM   3905  N N   . GLY B 1 41  ? -17.911 -42.657 -29.778 1.00 49.53  ? 41  GLY B N   1 
ATOM   3906  C CA  . GLY B 1 41  ? -16.901 -42.305 -28.806 1.00 53.74  ? 41  GLY B CA  1 
ATOM   3907  C C   . GLY B 1 41  ? -15.654 -43.173 -28.920 1.00 51.40  ? 41  GLY B C   1 
ATOM   3908  O O   . GLY B 1 41  ? -15.013 -43.448 -27.902 1.00 49.49  ? 41  GLY B O   1 
ATOM   3909  N N   . MET B 1 42  ? -15.346 -43.619 -30.145 1.00 44.17  ? 42  MET B N   1 
ATOM   3910  C CA  . MET B 1 42  ? -14.104 -44.308 -30.450 1.00 43.48  ? 42  MET B CA  1 
ATOM   3911  C C   . MET B 1 42  ? -13.974 -45.611 -29.667 1.00 41.34  ? 42  MET B C   1 
ATOM   3912  O O   . MET B 1 42  ? -12.839 -46.065 -29.464 1.00 43.53  ? 42  MET B O   1 
ATOM   3913  C CB  . MET B 1 42  ? -12.897 -43.446 -30.055 1.00 50.59  ? 42  MET B CB  1 
ATOM   3914  C CG  . MET B 1 42  ? -12.667 -42.216 -30.874 1.00 54.69  ? 42  MET B CG  1 
ATOM   3915  S SD  . MET B 1 42  ? -11.072 -41.481 -30.418 1.00 53.48  ? 42  MET B SD  1 
ATOM   3916  C CE  . MET B 1 42  ? -11.393 -39.781 -30.867 1.00 48.60  ? 42  MET B CE  1 
ATOM   3917  N N   . ARG B 1 43  ? -15.084 -46.193 -29.192 1.00 44.85  ? 43  ARG B N   1 
ATOM   3918  C CA  . ARG B 1 43  ? -14.986 -47.346 -28.298 1.00 50.60  ? 43  ARG B CA  1 
ATOM   3919  C C   . ARG B 1 43  ? -14.239 -48.482 -28.996 1.00 55.32  ? 43  ARG B C   1 
ATOM   3920  O O   . ARG B 1 43  ? -14.658 -48.939 -30.047 1.00 54.23  ? 43  ARG B O   1 
ATOM   3921  C CB  . ARG B 1 43  ? -16.364 -47.871 -27.892 1.00 56.16  ? 43  ARG B CB  1 
ATOM   3922  C CG  . ARG B 1 43  ? -16.356 -48.965 -26.827 1.00 67.77  ? 43  ARG B CG  1 
ATOM   3923  C CD  . ARG B 1 43  ? -16.275 -48.514 -25.362 1.00 81.32  ? 43  ARG B CD  1 
ATOM   3924  N NE  . ARG B 1 43  ? -17.351 -47.609 -24.927 1.00 84.16  ? 43  ARG B NE  1 
ATOM   3925  C CZ  . ARG B 1 43  ? -17.389 -46.290 -25.153 1.00 87.39  ? 43  ARG B CZ  1 
ATOM   3926  N NH1 . ARG B 1 43  ? -16.305 -45.647 -25.559 1.00 89.30  ? 43  ARG B NH1 1 
ATOM   3927  N NH2 . ARG B 1 43  ? -18.504 -45.604 -24.954 1.00 79.91  ? 43  ARG B NH2 1 
ATOM   3928  N N   . GLY B 1 44  ? -13.120 -48.921 -28.411 1.00 63.58  ? 44  GLY B N   1 
ATOM   3929  C CA  . GLY B 1 44  ? -12.363 -50.050 -28.924 1.00 52.62  ? 44  GLY B CA  1 
ATOM   3930  C C   . GLY B 1 44  ? -11.276 -49.645 -29.917 1.00 51.21  ? 44  GLY B C   1 
ATOM   3931  O O   . GLY B 1 44  ? -10.465 -50.482 -30.289 1.00 55.01  ? 44  GLY B O   1 
ATOM   3932  N N   . LEU B 1 45  ? -11.236 -48.372 -30.342 1.00 49.54  ? 45  LEU B N   1 
ATOM   3933  C CA  . LEU B 1 45  ? -10.322 -47.969 -31.405 1.00 47.56  ? 45  LEU B CA  1 
ATOM   3934  C C   . LEU B 1 45  ? -8.913  -47.736 -30.838 1.00 49.69  ? 45  LEU B C   1 
ATOM   3935  O O   . LEU B 1 45  ? -8.692  -46.941 -29.932 1.00 50.85  ? 45  LEU B O   1 
ATOM   3936  C CB  . LEU B 1 45  ? -10.898 -46.743 -32.124 1.00 46.24  ? 45  LEU B CB  1 
ATOM   3937  C CG  . LEU B 1 45  ? -10.134 -46.262 -33.362 1.00 53.88  ? 45  LEU B CG  1 
ATOM   3938  C CD1 . LEU B 1 45  ? -10.227 -47.262 -34.494 1.00 59.73  ? 45  LEU B CD1 1 
ATOM   3939  C CD2 . LEU B 1 45  ? -10.646 -44.914 -33.837 1.00 62.60  ? 45  LEU B CD2 1 
ATOM   3940  N N   . LYS B 1 46  ? -7.923  -48.438 -31.377 1.00 46.30  ? 46  LYS B N   1 
ATOM   3941  C CA  . LYS B 1 46  ? -6.624  -48.453 -30.744 1.00 43.63  ? 46  LYS B CA  1 
ATOM   3942  C C   . LYS B 1 46  ? -5.858  -47.225 -31.220 1.00 49.18  ? 46  LYS B C   1 
ATOM   3943  O O   . LYS B 1 46  ? -4.955  -47.329 -32.044 1.00 50.45  ? 46  LYS B O   1 
ATOM   3944  C CB  . LYS B 1 46  ? -5.923  -49.774 -31.061 1.00 45.40  ? 46  LYS B CB  1 
ATOM   3945  C CG  . LYS B 1 46  ? -6.598  -51.015 -30.495 1.00 47.66  ? 46  LYS B CG  1 
ATOM   3946  C CD  . LYS B 1 46  ? -5.803  -52.283 -30.766 1.00 55.15  ? 46  LYS B CD  1 
ATOM   3947  C CE  . LYS B 1 46  ? -6.667  -53.502 -31.017 1.00 65.20  ? 46  LYS B CE  1 
ATOM   3948  N NZ  . LYS B 1 46  ? -6.685  -54.429 -29.871 1.00 64.71  ? 46  LYS B NZ  1 
ATOM   3949  N N   . ALA B 1 47  ? -6.208  -46.056 -30.672 1.00 49.70  ? 47  ALA B N   1 
ATOM   3950  C CA  . ALA B 1 47  ? -5.754  -44.786 -31.228 1.00 47.33  ? 47  ALA B CA  1 
ATOM   3951  C C   . ALA B 1 47  ? -4.691  -44.078 -30.380 1.00 44.75  ? 47  ALA B C   1 
ATOM   3952  O O   . ALA B 1 47  ? -4.353  -42.938 -30.691 1.00 53.93  ? 47  ALA B O   1 
ATOM   3953  C CB  . ALA B 1 47  ? -6.959  -43.905 -31.405 1.00 48.02  ? 47  ALA B CB  1 
ATOM   3954  N N   . LEU B 1 48  ? -4.133  -44.754 -29.363 1.00 45.01  ? 48  LEU B N   1 
ATOM   3955  C CA  . LEU B 1 48  ? -3.398  -44.113 -28.276 1.00 55.35  ? 48  LEU B CA  1 
ATOM   3956  C C   . LEU B 1 48  ? -2.315  -45.049 -27.739 1.00 47.47  ? 48  LEU B C   1 
ATOM   3957  O O   . LEU B 1 48  ? -2.518  -46.243 -27.749 1.00 48.40  ? 48  LEU B O   1 
ATOM   3958  C CB  . LEU B 1 48  ? -4.381  -43.803 -27.132 1.00 66.86  ? 48  LEU B CB  1 
ATOM   3959  C CG  . LEU B 1 48  ? -4.994  -42.404 -27.082 1.00 63.20  ? 48  LEU B CG  1 
ATOM   3960  C CD1 . LEU B 1 48  ? -5.642  -42.169 -25.737 1.00 66.86  ? 48  LEU B CD1 1 
ATOM   3961  C CD2 . LEU B 1 48  ? -3.959  -41.327 -27.344 1.00 74.73  ? 48  LEU B CD2 1 
ATOM   3962  N N   . VAL B 1 49  ? -1.231  -44.479 -27.191 1.00 49.34  ? 49  VAL B N   1 
ATOM   3963  C CA  . VAL B 1 49  ? -0.134  -45.202 -26.563 1.00 46.51  ? 49  VAL B CA  1 
ATOM   3964  C C   . VAL B 1 49  ? -0.100  -44.891 -25.068 1.00 50.53  ? 49  VAL B C   1 
ATOM   3965  O O   . VAL B 1 49  ? -0.124  -43.742 -24.652 1.00 48.95  ? 49  VAL B O   1 
ATOM   3966  C CB  . VAL B 1 49  ? 1.232   -44.829 -27.171 1.00 48.03  ? 49  VAL B CB  1 
ATOM   3967  C CG1 . VAL B 1 49  ? 2.376   -45.544 -26.477 1.00 45.85  ? 49  VAL B CG1 1 
ATOM   3968  C CG2 . VAL B 1 49  ? 1.300   -45.099 -28.664 1.00 58.00  ? 49  VAL B CG2 1 
ATOM   3969  N N   . CYS B 1 50  ? 0.051   -45.939 -24.260 1.00 55.15  ? 50  CYS B N   1 
ATOM   3970  C CA  . CYS B 1 50  ? 0.317   -45.792 -22.841 1.00 52.54  ? 50  CYS B CA  1 
ATOM   3971  C C   . CYS B 1 50  ? 1.086   -47.035 -22.392 1.00 47.58  ? 50  CYS B C   1 
ATOM   3972  O O   . CYS B 1 50  ? 0.598   -48.141 -22.618 1.00 42.20  ? 50  CYS B O   1 
ATOM   3973  C CB  . CYS B 1 50  ? -0.984  -45.629 -22.046 1.00 54.23  ? 50  CYS B CB  1 
ATOM   3974  S SG  . CYS B 1 50  ? -0.779  -45.900 -20.260 1.00 52.27  ? 50  CYS B SG  1 
ATOM   3975  N N   . ASP B 1 51  ? 2.258   -46.817 -21.764 1.00 42.54  ? 51  ASP B N   1 
ATOM   3976  C CA  . ASP B 1 51  ? 3.157   -47.868 -21.324 1.00 43.86  ? 51  ASP B CA  1 
ATOM   3977  C C   . ASP B 1 51  ? 3.191   -48.015 -19.805 1.00 48.08  ? 51  ASP B C   1 
ATOM   3978  O O   . ASP B 1 51  ? 3.968   -48.828 -19.306 1.00 50.44  ? 51  ASP B O   1 
ATOM   3979  C CB  . ASP B 1 51  ? 4.590   -47.597 -21.780 1.00 49.40  ? 51  ASP B CB  1 
ATOM   3980  C CG  . ASP B 1 51  ? 4.778   -47.906 -23.258 1.00 53.63  ? 51  ASP B CG  1 
ATOM   3981  O OD1 . ASP B 1 51  ? 4.117   -48.831 -23.718 1.00 50.00  ? 51  ASP B OD1 1 
ATOM   3982  O OD2 . ASP B 1 51  ? 5.580   -47.219 -23.925 1.00 53.19  ? 51  ASP B OD2 1 
ATOM   3983  N N   . THR B 1 52  ? 2.381   -47.242 -19.063 1.00 43.06  ? 52  THR B N   1 
ATOM   3984  C CA  . THR B 1 52  ? 2.535   -47.211 -17.614 1.00 42.36  ? 52  THR B CA  1 
ATOM   3985  C C   . THR B 1 52  ? 1.831   -48.413 -17.021 1.00 39.84  ? 52  THR B C   1 
ATOM   3986  O O   . THR B 1 52  ? 2.325   -49.011 -16.067 1.00 43.93  ? 52  THR B O   1 
ATOM   3987  C CB  . THR B 1 52  ? 2.019   -45.919 -16.954 1.00 40.78  ? 52  THR B CB  1 
ATOM   3988  O OG1 . THR B 1 52  ? 0.711   -45.572 -17.419 1.00 41.82  ? 52  THR B OG1 1 
ATOM   3989  C CG2 . THR B 1 52  ? 2.961   -44.770 -17.203 1.00 47.55  ? 52  THR B CG2 1 
ATOM   3990  N N   . SER B 1 53  ? 0.645   -48.662 -17.581 1.00 38.19  ? 53  SER B N   1 
ATOM   3991  C CA  . SER B 1 53  ? -0.269  -49.683 -17.150 1.00 40.18  ? 53  SER B CA  1 
ATOM   3992  C C   . SER B 1 53  ? -0.980  -50.286 -18.369 1.00 44.13  ? 53  SER B C   1 
ATOM   3993  O O   . SER B 1 53  ? -0.876  -49.799 -19.496 1.00 51.81  ? 53  SER B O   1 
ATOM   3994  C CB  . SER B 1 53  ? -1.212  -49.146 -16.105 1.00 39.21  ? 53  SER B CB  1 
ATOM   3995  O OG  . SER B 1 53  ? -2.090  -48.159 -16.614 1.00 47.09  ? 53  SER B OG  1 
ATOM   3996  N N   . GLU B 1 54  ? -1.651  -51.416 -18.149 1.00 52.58  ? 54  GLU B N   1 
ATOM   3997  C CA  . GLU B 1 54  ? -2.183  -52.233 -19.231 1.00 51.06  ? 54  GLU B CA  1 
ATOM   3998  C C   . GLU B 1 54  ? -3.202  -53.167 -18.608 1.00 47.65  ? 54  GLU B C   1 
ATOM   3999  O O   . GLU B 1 54  ? -2.874  -53.886 -17.653 1.00 54.20  ? 54  GLU B O   1 
ATOM   4000  C CB  . GLU B 1 54  ? -1.086  -53.040 -19.959 1.00 52.97  ? 54  GLU B CB  1 
ATOM   4001  C CG  . GLU B 1 54  ? -1.623  -53.941 -21.082 1.00 55.66  ? 54  GLU B CG  1 
ATOM   4002  C CD  . GLU B 1 54  ? -0.627  -54.494 -22.102 1.00 63.34  ? 54  GLU B CD  1 
ATOM   4003  O OE1 . GLU B 1 54  ? -1.103  -54.949 -23.181 1.00 68.41  ? 54  GLU B OE1 1 
ATOM   4004  O OE2 . GLU B 1 54  ? 0.615   -54.494 -21.829 1.00 50.32  ? 54  GLU B OE2 1 
ATOM   4005  N N   . VAL B 1 55  ? -4.413  -53.108 -19.160 1.00 52.09  ? 55  VAL B N   1 
ATOM   4006  C CA  . VAL B 1 55  ? -5.514  -53.954 -18.746 1.00 61.51  ? 55  VAL B CA  1 
ATOM   4007  C C   . VAL B 1 55  ? -5.466  -55.255 -19.547 1.00 65.49  ? 55  VAL B C   1 
ATOM   4008  O O   . VAL B 1 55  ? -5.493  -55.221 -20.777 1.00 64.20  ? 55  VAL B O   1 
ATOM   4009  C CB  . VAL B 1 55  ? -6.858  -53.232 -18.956 1.00 63.20  ? 55  VAL B CB  1 
ATOM   4010  C CG1 . VAL B 1 55  ? -8.044  -54.185 -18.891 1.00 63.46  ? 55  VAL B CG1 1 
ATOM   4011  C CG2 . VAL B 1 55  ? -7.018  -52.092 -17.970 1.00 69.12  ? 55  VAL B CG2 1 
ATOM   4012  N N   . PHE B 1 56  ? -5.397  -56.395 -18.840 1.00 60.53  ? 56  PHE B N   1 
ATOM   4013  C CA  . PHE B 1 56  ? -5.599  -57.693 -19.461 1.00 59.16  ? 56  PHE B CA  1 
ATOM   4014  C C   . PHE B 1 56  ? -6.939  -58.274 -19.040 1.00 57.52  ? 56  PHE B C   1 
ATOM   4015  O O   . PHE B 1 56  ? -7.198  -58.365 -17.844 1.00 57.19  ? 56  PHE B O   1 
ATOM   4016  C CB  . PHE B 1 56  ? -4.491  -58.649 -19.057 1.00 64.14  ? 56  PHE B CB  1 
ATOM   4017  C CG  . PHE B 1 56  ? -3.113  -58.205 -19.465 1.00 63.44  ? 56  PHE B CG  1 
ATOM   4018  C CD1 . PHE B 1 56  ? -2.441  -57.238 -18.734 1.00 60.16  ? 56  PHE B CD1 1 
ATOM   4019  C CD2 . PHE B 1 56  ? -2.503  -58.746 -20.592 1.00 66.95  ? 56  PHE B CD2 1 
ATOM   4020  C CE1 . PHE B 1 56  ? -1.151  -56.852 -19.091 1.00 73.14  ? 56  PHE B CE1 1 
ATOM   4021  C CE2 . PHE B 1 56  ? -1.216  -58.366 -20.950 1.00 78.48  ? 56  PHE B CE2 1 
ATOM   4022  C CZ  . PHE B 1 56  ? -0.539  -57.417 -20.197 1.00 83.15  ? 56  PHE B CZ  1 
ATOM   4023  N N   . PRO B 1 57  ? -7.798  -58.735 -19.984 1.00 60.19  ? 57  PRO B N   1 
ATOM   4024  C CA  . PRO B 1 57  ? -9.121  -59.266 -19.628 1.00 68.57  ? 57  PRO B CA  1 
ATOM   4025  C C   . PRO B 1 57  ? -9.132  -60.354 -18.543 1.00 66.32  ? 57  PRO B C   1 
ATOM   4026  O O   . PRO B 1 57  ? -10.028 -60.384 -17.684 1.00 60.62  ? 57  PRO B O   1 
ATOM   4027  C CB  . PRO B 1 57  ? -9.629  -59.804 -20.978 1.00 61.82  ? 57  PRO B CB  1 
ATOM   4028  C CG  . PRO B 1 57  ? -8.946  -58.944 -22.012 1.00 55.51  ? 57  PRO B CG  1 
ATOM   4029  C CD  . PRO B 1 57  ? -7.559  -58.747 -21.440 1.00 56.59  ? 57  PRO B CD  1 
ATOM   4030  N N   . ASP B 1 58  ? -8.088  -61.192 -18.545 1.00 66.75  ? 58  ASP B N   1 
ATOM   4031  C CA  . ASP B 1 58  ? -7.992  -62.312 -17.621 1.00 75.33  ? 58  ASP B CA  1 
ATOM   4032  C C   . ASP B 1 58  ? -7.251  -61.994 -16.311 1.00 67.20  ? 58  ASP B C   1 
ATOM   4033  O O   . ASP B 1 58  ? -7.242  -62.832 -15.415 1.00 59.07  ? 58  ASP B O   1 
ATOM   4034  C CB  . ASP B 1 58  ? -7.354  -63.513 -18.329 1.00 82.39  ? 58  ASP B CB  1 
ATOM   4035  C CG  . ASP B 1 58  ? -8.363  -64.547 -18.804 1.00 93.78  ? 58  ASP B CG  1 
ATOM   4036  O OD1 . ASP B 1 58  ? -9.552  -64.424 -18.436 1.00 105.82 ? 58  ASP B OD1 1 
ATOM   4037  O OD2 . ASP B 1 58  ? -7.954  -65.484 -19.519 1.00 104.84 ? 58  ASP B OD2 1 
ATOM   4038  N N   . GLU B 1 59  ? -6.606  -60.830 -16.174 1.00 72.16  ? 59  GLU B N   1 
ATOM   4039  C CA  . GLU B 1 59  ? -5.846  -60.516 -14.962 1.00 67.07  ? 59  GLU B CA  1 
ATOM   4040  C C   . GLU B 1 59  ? -6.265  -59.180 -14.346 1.00 67.99  ? 59  GLU B C   1 
ATOM   4041  O O   . GLU B 1 59  ? -6.020  -58.957 -13.164 1.00 59.62  ? 59  GLU B O   1 
ATOM   4042  C CB  . GLU B 1 59  ? -4.350  -60.408 -15.249 1.00 63.29  ? 59  GLU B CB  1 
ATOM   4043  C CG  . GLU B 1 59  ? -3.773  -61.629 -15.917 1.00 69.23  ? 59  GLU B CG  1 
ATOM   4044  C CD  . GLU B 1 59  ? -2.288  -61.551 -16.226 1.00 73.43  ? 59  GLU B CD  1 
ATOM   4045  O OE1 . GLU B 1 59  ? -1.517  -61.183 -15.307 1.00 83.89  ? 59  GLU B OE1 1 
ATOM   4046  O OE2 . GLU B 1 59  ? -1.907  -61.889 -17.376 1.00 81.20  ? 59  GLU B OE2 1 
ATOM   4047  N N   . GLY B 1 60  ? -6.862  -58.284 -15.148 1.00 66.14  ? 60  GLY B N   1 
ATOM   4048  C CA  . GLY B 1 60  ? -7.108  -56.911 -14.727 1.00 64.76  ? 60  GLY B CA  1 
ATOM   4049  C C   . GLY B 1 60  ? -5.912  -56.007 -15.029 1.00 57.83  ? 60  GLY B C   1 
ATOM   4050  O O   . GLY B 1 60  ? -5.116  -56.290 -15.933 1.00 56.01  ? 60  GLY B O   1 
ATOM   4051  N N   . VAL B 1 61  ? -5.765  -54.932 -14.243 1.00 46.84  ? 61  VAL B N   1 
ATOM   4052  C CA  . VAL B 1 61  ? -4.812  -53.914 -14.595 1.00 43.92  ? 61  VAL B CA  1 
ATOM   4053  C C   . VAL B 1 61  ? -3.467  -54.410 -14.096 1.00 47.13  ? 61  VAL B C   1 
ATOM   4054  O O   . VAL B 1 61  ? -3.407  -55.052 -13.051 1.00 48.15  ? 61  VAL B O   1 
ATOM   4055  C CB  . VAL B 1 61  ? -5.186  -52.528 -14.027 1.00 49.15  ? 61  VAL B CB  1 
ATOM   4056  C CG1 . VAL B 1 61  ? -5.044  -52.425 -12.502 1.00 44.99  ? 61  VAL B CG1 1 
ATOM   4057  C CG2 . VAL B 1 61  ? -4.348  -51.458 -14.683 1.00 44.97  ? 61  VAL B CG2 1 
ATOM   4058  N N   . LYS B 1 62  ? -2.414  -54.154 -14.873 1.00 44.88  ? 62  LYS B N   1 
ATOM   4059  C CA  . LYS B 1 62  ? -1.063  -54.328 -14.374 1.00 49.62  ? 62  LYS B CA  1 
ATOM   4060  C C   . LYS B 1 62  ? -0.314  -53.000 -14.457 1.00 46.77  ? 62  LYS B C   1 
ATOM   4061  O O   . LYS B 1 62  ? -0.580  -52.168 -15.312 1.00 51.78  ? 62  LYS B O   1 
ATOM   4062  C CB  . LYS B 1 62  ? -0.323  -55.440 -15.128 1.00 57.45  ? 62  LYS B CB  1 
ATOM   4063  C CG  . LYS B 1 62  ? -1.015  -56.800 -15.113 1.00 63.89  ? 62  LYS B CG  1 
ATOM   4064  C CD  . LYS B 1 62  ? -0.065  -58.004 -15.027 1.00 74.03  ? 62  LYS B CD  1 
ATOM   4065  C CE  . LYS B 1 62  ? 0.639   -58.343 -16.326 1.00 76.90  ? 62  LYS B CE  1 
ATOM   4066  N NZ  . LYS B 1 62  ? 1.166   -59.731 -16.342 1.00 71.30  ? 62  LYS B NZ  1 
ATOM   4067  N N   . PHE B 1 63  ? 0.666   -52.848 -13.584 1.00 42.29  ? 63  PHE B N   1 
ATOM   4068  C CA  . PHE B 1 63  ? 1.467   -51.657 -13.514 1.00 48.40  ? 63  PHE B CA  1 
ATOM   4069  C C   . PHE B 1 63  ? 2.863   -52.039 -13.961 1.00 49.29  ? 63  PHE B C   1 
ATOM   4070  O O   . PHE B 1 63  ? 3.566   -52.690 -13.209 1.00 50.41  ? 63  PHE B O   1 
ATOM   4071  C CB  . PHE B 1 63  ? 1.497   -51.101 -12.083 1.00 49.78  ? 63  PHE B CB  1 
ATOM   4072  C CG  . PHE B 1 63  ? 0.163   -50.684 -11.511 1.00 50.62  ? 63  PHE B CG  1 
ATOM   4073  C CD1 . PHE B 1 63  ? -0.701  -49.870 -12.229 1.00 56.28  ? 63  PHE B CD1 1 
ATOM   4074  C CD2 . PHE B 1 63  ? -0.209  -51.053 -10.231 1.00 56.35  ? 63  PHE B CD2 1 
ATOM   4075  C CE1 . PHE B 1 63  ? -1.929  -49.491 -11.707 1.00 53.68  ? 63  PHE B CE1 1 
ATOM   4076  C CE2 . PHE B 1 63  ? -1.426  -50.651 -9.696  1.00 56.08  ? 63  PHE B CE2 1 
ATOM   4077  C CZ  . PHE B 1 63  ? -2.283  -49.877 -10.438 1.00 60.24  ? 63  PHE B CZ  1 
ATOM   4078  N N   . ARG B 1 64  ? 3.239   -51.626 -15.175 1.00 48.09  ? 64  ARG B N   1 
ATOM   4079  C CA  . ARG B 1 64  ? 4.509   -52.000 -15.772 1.00 49.42  ? 64  ARG B CA  1 
ATOM   4080  C C   . ARG B 1 64  ? 4.765   -53.512 -15.704 1.00 49.69  ? 64  ARG B C   1 
ATOM   4081  O O   . ARG B 1 64  ? 5.911   -53.952 -15.524 1.00 46.76  ? 64  ARG B O   1 
ATOM   4082  C CB  . ARG B 1 64  ? 5.627   -51.232 -15.074 1.00 49.01  ? 64  ARG B CB  1 
ATOM   4083  C CG  . ARG B 1 64  ? 5.690   -49.770 -15.477 1.00 52.41  ? 64  ARG B CG  1 
ATOM   4084  C CD  . ARG B 1 64  ? 6.120   -49.606 -16.909 1.00 44.09  ? 64  ARG B CD  1 
ATOM   4085  N NE  . ARG B 1 64  ? 6.526   -48.245 -17.126 1.00 44.84  ? 64  ARG B NE  1 
ATOM   4086  C CZ  . ARG B 1 64  ? 7.164   -47.827 -18.213 1.00 52.15  ? 64  ARG B CZ  1 
ATOM   4087  N NH1 . ARG B 1 64  ? 7.291   -48.628 -19.252 1.00 50.75  ? 64  ARG B NH1 1 
ATOM   4088  N NH2 . ARG B 1 64  ? 7.640   -46.597 -18.282 1.00 53.56  ? 64  ARG B NH2 1 
ATOM   4089  N N   . GLY B 1 65  ? 3.724   -54.320 -15.904 1.00 47.67  ? 65  GLY B N   1 
ATOM   4090  C CA  . GLY B 1 65  ? 3.938   -55.757 -15.979 1.00 60.29  ? 65  GLY B CA  1 
ATOM   4091  C C   . GLY B 1 65  ? 3.651   -56.486 -14.667 1.00 63.04  ? 65  GLY B C   1 
ATOM   4092  O O   . GLY B 1 65  ? 3.177   -57.625 -14.686 1.00 72.51  ? 65  GLY B O   1 
ATOM   4093  N N   . TYR B 1 66  ? 3.878   -55.811 -13.535 1.00 55.99  ? 66  TYR B N   1 
ATOM   4094  C CA  . TYR B 1 66  ? 3.610   -56.399 -12.226 1.00 53.76  ? 66  TYR B CA  1 
ATOM   4095  C C   . TYR B 1 66  ? 2.129   -56.296 -11.875 1.00 49.02  ? 66  TYR B C   1 
ATOM   4096  O O   . TYR B 1 66  ? 1.461   -55.324 -12.199 1.00 59.33  ? 66  TYR B O   1 
ATOM   4097  C CB  . TYR B 1 66  ? 4.465   -55.748 -11.142 1.00 50.32  ? 66  TYR B CB  1 
ATOM   4098  C CG  . TYR B 1 66  ? 5.951   -55.847 -11.383 1.00 53.45  ? 66  TYR B CG  1 
ATOM   4099  C CD1 . TYR B 1 66  ? 6.687   -56.961 -10.982 1.00 48.49  ? 66  TYR B CD1 1 
ATOM   4100  C CD2 . TYR B 1 66  ? 6.620   -54.823 -12.045 1.00 56.01  ? 66  TYR B CD2 1 
ATOM   4101  C CE1 . TYR B 1 66  ? 8.063   -57.020 -11.180 1.00 52.13  ? 66  TYR B CE1 1 
ATOM   4102  C CE2 . TYR B 1 66  ? 7.987   -54.886 -12.288 1.00 59.81  ? 66  TYR B CE2 1 
ATOM   4103  C CZ  . TYR B 1 66  ? 8.713   -55.981 -11.840 1.00 55.28  ? 66  TYR B CZ  1 
ATOM   4104  O OH  . TYR B 1 66  ? 10.048  -55.985 -12.118 1.00 47.67  ? 66  TYR B OH  1 
ATOM   4105  N N   . THR B 1 67  ? 1.615   -57.350 -11.245 1.00 52.30  ? 67  THR B N   1 
ATOM   4106  C CA  . THR B 1 67  ? 0.254   -57.398 -10.740 1.00 54.14  ? 67  THR B CA  1 
ATOM   4107  C C   . THR B 1 67  ? 0.210   -56.620 -9.425  1.00 50.67  ? 67  THR B C   1 
ATOM   4108  O O   . THR B 1 67  ? 1.254   -56.313 -8.843  1.00 54.27  ? 67  THR B O   1 
ATOM   4109  C CB  . THR B 1 67  ? -0.202  -58.846 -10.478 1.00 54.64  ? 67  THR B CB  1 
ATOM   4110  O OG1 . THR B 1 67  ? 0.573   -59.337 -9.377  1.00 41.66  ? 67  THR B OG1 1 
ATOM   4111  C CG2 . THR B 1 67  ? -0.058  -59.743 -11.687 1.00 51.44  ? 67  THR B CG2 1 
ATOM   4112  N N   . ILE B 1 68  ? -1.003  -56.338 -8.956  1.00 42.32  ? 68  ILE B N   1 
ATOM   4113  C CA  . ILE B 1 68  ? -1.192  -55.687 -7.670  1.00 57.18  ? 68  ILE B CA  1 
ATOM   4114  C C   . ILE B 1 68  ? -0.635  -56.582 -6.554  1.00 54.12  ? 68  ILE B C   1 
ATOM   4115  O O   . ILE B 1 68  ? 0.208   -56.124 -5.774  1.00 44.02  ? 68  ILE B O   1 
ATOM   4116  C CB  . ILE B 1 68  ? -2.683  -55.311 -7.490  1.00 55.46  ? 68  ILE B CB  1 
ATOM   4117  C CG1 . ILE B 1 68  ? -2.994  -54.001 -8.227  1.00 55.52  ? 68  ILE B CG1 1 
ATOM   4118  C CG2 . ILE B 1 68  ? -3.062  -55.267 -6.011  1.00 53.06  ? 68  ILE B CG2 1 
ATOM   4119  C CD1 . ILE B 1 68  ? -4.458  -53.793 -8.574  1.00 56.70  ? 68  ILE B CD1 1 
ATOM   4120  N N   . PRO B 1 69  ? -1.070  -57.868 -6.452  1.00 56.08  ? 69  PRO B N   1 
ATOM   4121  C CA  . PRO B 1 69  ? -0.532  -58.785 -5.456  1.00 54.23  ? 69  PRO B CA  1 
ATOM   4122  C C   . PRO B 1 69  ? 0.990   -58.864 -5.429  1.00 50.55  ? 69  PRO B C   1 
ATOM   4123  O O   . PRO B 1 69  ? 1.544   -58.841 -4.344  1.00 52.51  ? 69  PRO B O   1 
ATOM   4124  C CB  . PRO B 1 69  ? -1.202  -60.105 -5.823  1.00 52.43  ? 69  PRO B CB  1 
ATOM   4125  C CG  . PRO B 1 69  ? -2.550  -59.661 -6.308  1.00 58.23  ? 69  PRO B CG  1 
ATOM   4126  C CD  . PRO B 1 69  ? -2.175  -58.498 -7.205  1.00 62.40  ? 69  PRO B CD  1 
ATOM   4127  N N   . GLU B 1 70  ? 1.675   -58.903 -6.577  1.00 46.07  ? 70  GLU B N   1 
ATOM   4128  C CA  . GLU B 1 70  ? 3.139   -58.925 -6.546  1.00 51.52  ? 70  GLU B CA  1 
ATOM   4129  C C   . GLU B 1 70  ? 3.697   -57.736 -5.756  1.00 53.20  ? 70  GLU B C   1 
ATOM   4130  O O   . GLU B 1 70  ? 4.672   -57.901 -5.023  1.00 47.75  ? 70  GLU B O   1 
ATOM   4131  C CB  . GLU B 1 70  ? 3.754   -58.938 -7.954  1.00 58.18  ? 70  GLU B CB  1 
ATOM   4132  C CG  . GLU B 1 70  ? 3.478   -60.215 -8.746  1.00 66.63  ? 70  GLU B CG  1 
ATOM   4133  C CD  . GLU B 1 70  ? 4.099   -60.259 -10.141 1.00 79.28  ? 70  GLU B CD  1 
ATOM   4134  O OE1 . GLU B 1 70  ? 4.770   -61.274 -10.464 1.00 86.20  ? 70  GLU B OE1 1 
ATOM   4135  O OE2 . GLU B 1 70  ? 3.955   -59.266 -10.898 1.00 68.31  ? 70  GLU B OE2 1 
ATOM   4136  N N   . LEU B 1 71  ? 3.078   -56.545 -5.918  1.00 58.92  ? 71  LEU B N   1 
ATOM   4137  C CA  . LEU B 1 71  ? 3.578   -55.282 -5.372  1.00 56.80  ? 71  LEU B CA  1 
ATOM   4138  C C   . LEU B 1 71  ? 3.107   -55.046 -3.932  1.00 53.02  ? 71  LEU B C   1 
ATOM   4139  O O   . LEU B 1 71  ? 3.820   -54.454 -3.110  1.00 51.89  ? 71  LEU B O   1 
ATOM   4140  C CB  . LEU B 1 71  ? 3.086   -54.150 -6.277  1.00 52.01  ? 71  LEU B CB  1 
ATOM   4141  C CG  . LEU B 1 71  ? 3.571   -54.211 -7.724  1.00 48.06  ? 71  LEU B CG  1 
ATOM   4142  C CD1 . LEU B 1 71  ? 2.809   -53.225 -8.599  1.00 48.77  ? 71  LEU B CD1 1 
ATOM   4143  C CD2 . LEU B 1 71  ? 5.069   -53.935 -7.810  1.00 46.65  ? 71  LEU B CD2 1 
ATOM   4144  N N   . ARG B 1 72  ? 1.881   -55.497 -3.666  1.00 49.13  ? 72  ARG B N   1 
ATOM   4145  C CA  . ARG B 1 72  ? 1.233   -55.367 -2.379  1.00 56.43  ? 72  ARG B CA  1 
ATOM   4146  C C   . ARG B 1 72  ? 1.713   -56.410 -1.357  1.00 69.37  ? 72  ARG B C   1 
ATOM   4147  O O   . ARG B 1 72  ? 1.911   -56.090 -0.178  1.00 62.65  ? 72  ARG B O   1 
ATOM   4148  C CB  . ARG B 1 72  ? -0.268  -55.514 -2.615  1.00 55.21  ? 72  ARG B CB  1 
ATOM   4149  C CG  . ARG B 1 72  ? -1.073  -55.109 -1.399  1.00 62.93  ? 72  ARG B CG  1 
ATOM   4150  C CD  . ARG B 1 72  ? -2.514  -54.788 -1.725  1.00 62.52  ? 72  ARG B CD  1 
ATOM   4151  N NE  . ARG B 1 72  ? -3.130  -54.502 -0.433  1.00 62.09  ? 72  ARG B NE  1 
ATOM   4152  C CZ  . ARG B 1 72  ? -3.852  -55.376 0.250   1.00 60.85  ? 72  ARG B CZ  1 
ATOM   4153  N NH1 . ARG B 1 72  ? -4.207  -56.505 -0.329  1.00 52.25  ? 72  ARG B NH1 1 
ATOM   4154  N NH2 . ARG B 1 72  ? -4.216  -55.117 1.498   1.00 68.32  ? 72  ARG B NH2 1 
ATOM   4155  N N   . GLU B 1 73  ? 1.855   -57.670 -1.792  1.00 68.51  ? 73  GLU B N   1 
ATOM   4156  C CA  . GLU B 1 73  ? 2.160   -58.761 -0.868  1.00 77.60  ? 73  GLU B CA  1 
ATOM   4157  C C   . GLU B 1 73  ? 3.310   -59.633 -1.362  1.00 72.20  ? 73  GLU B C   1 
ATOM   4158  O O   . GLU B 1 73  ? 4.231   -59.891 -0.596  1.00 66.93  ? 73  GLU B O   1 
ATOM   4159  C CB  . GLU B 1 73  ? 0.940   -59.642 -0.575  1.00 75.97  ? 73  GLU B CB  1 
ATOM   4160  C CG  . GLU B 1 73  ? -0.058  -59.790 -1.706  1.00 77.64  ? 73  GLU B CG  1 
ATOM   4161  C CD  . GLU B 1 73  ? -1.407  -60.306 -1.225  1.00 77.29  ? 73  GLU B CD  1 
ATOM   4162  O OE1 . GLU B 1 73  ? -2.311  -60.487 -2.051  1.00 82.95  ? 73  GLU B OE1 1 
ATOM   4163  O OE2 . GLU B 1 73  ? -1.547  -60.526 -0.015  1.00 84.42  ? 73  GLU B OE2 1 
ATOM   4164  N N   . GLY B 1 74  ? 3.187   -60.055 -2.615  1.00 75.38  ? 74  GLY B N   1 
ATOM   4165  C CA  . GLY B 1 74  ? 4.089   -61.046 -3.208  1.00 78.96  ? 74  GLY B CA  1 
ATOM   4166  C C   . GLY B 1 74  ? 5.575   -60.830 -3.163  1.00 81.05  ? 74  GLY B C   1 
ATOM   4167  O O   . GLY B 1 74  ? 6.078   -59.982 -2.416  1.00 78.32  ? 74  GLY B O   1 
ATOM   4168  N N   . PRO B 1 75  ? 6.303   -61.528 -4.041  1.00 89.68  ? 75  PRO B N   1 
ATOM   4169  C CA  . PRO B 1 75  ? 7.769   -61.517 -3.973  1.00 86.03  ? 75  PRO B CA  1 
ATOM   4170  C C   . PRO B 1 75  ? 8.443   -60.197 -4.369  1.00 79.32  ? 75  PRO B C   1 
ATOM   4171  O O   . PRO B 1 75  ? 9.629   -60.007 -4.102  1.00 78.72  ? 75  PRO B O   1 
ATOM   4172  C CB  . PRO B 1 75  ? 8.164   -62.653 -4.940  1.00 80.34  ? 75  PRO B CB  1 
ATOM   4173  C CG  . PRO B 1 75  ? 7.037   -62.698 -5.968  1.00 79.42  ? 75  PRO B CG  1 
ATOM   4174  C CD  . PRO B 1 75  ? 5.794   -62.274 -5.208  1.00 89.94  ? 75  PRO B CD  1 
ATOM   4175  N N   . HIS B 1 76  ? 7.685   -59.277 -4.984  1.00 77.65  ? 76  HIS B N   1 
ATOM   4176  C CA  . HIS B 1 76  ? 8.218   -57.980 -5.383  1.00 80.17  ? 76  HIS B CA  1 
ATOM   4177  C C   . HIS B 1 76  ? 7.568   -56.835 -4.592  1.00 67.74  ? 76  HIS B C   1 
ATOM   4178  O O   . HIS B 1 76  ? 7.277   -55.796 -5.164  1.00 69.36  ? 76  HIS B O   1 
ATOM   4179  C CB  . HIS B 1 76  ? 8.025   -57.794 -6.897  1.00 82.14  ? 76  HIS B CB  1 
ATOM   4180  C CG  . HIS B 1 76  ? 8.649   -58.851 -7.763  1.00 83.66  ? 76  HIS B CG  1 
ATOM   4181  N ND1 . HIS B 1 76  ? 7.888   -59.810 -8.404  1.00 73.91  ? 76  HIS B ND1 1 
ATOM   4182  C CD2 . HIS B 1 76  ? 9.934   -59.104 -8.093  1.00 78.40  ? 76  HIS B CD2 1 
ATOM   4183  C CE1 . HIS B 1 76  ? 8.688   -60.594 -9.113  1.00 77.58  ? 76  HIS B CE1 1 
ATOM   4184  N NE2 . HIS B 1 76  ? 9.933   -60.181 -8.942  1.00 73.69  ? 76  HIS B NE2 1 
ATOM   4185  N N   . LYS B 1 77  ? 7.365   -56.996 -3.274  1.00 59.53  ? 77  LYS B N   1 
ATOM   4186  C CA  . LYS B 1 77  ? 6.545   -56.070 -2.503  1.00 56.46  ? 77  LYS B CA  1 
ATOM   4187  C C   . LYS B 1 77  ? 7.207   -54.694 -2.463  1.00 52.83  ? 77  LYS B C   1 
ATOM   4188  O O   . LYS B 1 77  ? 8.394   -54.562 -2.136  1.00 47.64  ? 77  LYS B O   1 
ATOM   4189  C CB  . LYS B 1 77  ? 6.329   -56.604 -1.088  1.00 60.82  ? 77  LYS B CB  1 
ATOM   4190  C CG  . LYS B 1 77  ? 5.463   -55.753 -0.169  1.00 65.79  ? 77  LYS B CG  1 
ATOM   4191  C CD  . LYS B 1 77  ? 5.572   -56.214 1.273   1.00 65.10  ? 77  LYS B CD  1 
ATOM   4192  C CE  . LYS B 1 77  ? 4.845   -55.333 2.263   1.00 67.56  ? 77  LYS B CE  1 
ATOM   4193  N NZ  . LYS B 1 77  ? 3.393   -55.273 1.969   1.00 71.16  ? 77  LYS B NZ  1 
ATOM   4194  N N   . LEU B 1 78  ? 6.419   -53.661 -2.786  1.00 51.22  ? 78  LEU B N   1 
ATOM   4195  C CA  . LEU B 1 78  ? 6.904   -52.282 -2.755  1.00 51.76  ? 78  LEU B CA  1 
ATOM   4196  C C   . LEU B 1 78  ? 7.095   -51.817 -1.312  1.00 47.83  ? 78  LEU B C   1 
ATOM   4197  O O   . LEU B 1 78  ? 6.296   -52.136 -0.439  1.00 50.62  ? 78  LEU B O   1 
ATOM   4198  C CB  . LEU B 1 78  ? 5.894   -51.381 -3.477  1.00 50.47  ? 78  LEU B CB  1 
ATOM   4199  C CG  . LEU B 1 78  ? 5.837   -51.530 -5.000  1.00 48.66  ? 78  LEU B CG  1 
ATOM   4200  C CD1 . LEU B 1 78  ? 4.641   -50.787 -5.583  1.00 46.52  ? 78  LEU B CD1 1 
ATOM   4201  C CD2 . LEU B 1 78  ? 7.127   -51.021 -5.631  1.00 52.89  ? 78  LEU B CD2 1 
ATOM   4202  N N   . PRO B 1 79  ? 8.096   -50.953 -1.040  1.00 54.87  ? 79  PRO B N   1 
ATOM   4203  C CA  . PRO B 1 79  ? 8.248   -50.342 0.284   1.00 54.20  ? 79  PRO B CA  1 
ATOM   4204  C C   . PRO B 1 79  ? 6.971   -49.750 0.894   1.00 54.95  ? 79  PRO B C   1 
ATOM   4205  O O   . PRO B 1 79  ? 6.086   -49.277 0.172   1.00 51.48  ? 79  PRO B O   1 
ATOM   4206  C CB  . PRO B 1 79  ? 9.258   -49.216 0.020   1.00 55.15  ? 79  PRO B CB  1 
ATOM   4207  C CG  . PRO B 1 79  ? 10.090  -49.741 -1.144  1.00 57.65  ? 79  PRO B CG  1 
ATOM   4208  C CD  . PRO B 1 79  ? 9.075   -50.443 -2.020  1.00 56.00  ? 79  PRO B CD  1 
ATOM   4209  N N   . THR B 1 80  ? 6.914   -49.796 2.240   1.00 56.02  ? 80  THR B N   1 
ATOM   4210  C CA  . THR B 1 80  ? 5.810   -49.333 3.074   1.00 51.33  ? 80  THR B CA  1 
ATOM   4211  C C   . THR B 1 80  ? 6.275   -48.174 3.946   1.00 56.08  ? 80  THR B C   1 
ATOM   4212  O O   . THR B 1 80  ? 7.447   -47.788 3.932   1.00 60.06  ? 80  THR B O   1 
ATOM   4213  C CB  . THR B 1 80  ? 5.319   -50.453 4.002   1.00 60.57  ? 80  THR B CB  1 
ATOM   4214  O OG1 . THR B 1 80  ? 6.428   -50.835 4.839   1.00 49.78  ? 80  THR B OG1 1 
ATOM   4215  C CG2 . THR B 1 80  ? 4.790   -51.646 3.233   1.00 64.76  ? 80  THR B CG2 1 
ATOM   4216  N N   . ALA B 1 81  ? 5.332   -47.619 4.716   1.00 64.72  ? 81  ALA B N   1 
ATOM   4217  C CA  . ALA B 1 81  ? 5.664   -46.791 5.867   1.00 66.10  ? 81  ALA B CA  1 
ATOM   4218  C C   . ALA B 1 81  ? 6.234   -47.698 6.956   1.00 64.76  ? 81  ALA B C   1 
ATOM   4219  O O   . ALA B 1 81  ? 5.921   -48.895 6.990   1.00 57.06  ? 81  ALA B O   1 
ATOM   4220  C CB  . ALA B 1 81  ? 4.416   -46.075 6.350   1.00 61.39  ? 81  ALA B CB  1 
ATOM   4221  N N   . GLU B 1 82  ? 7.016   -47.122 7.881   1.00 76.56  ? 82  GLU B N   1 
ATOM   4222  C CA  . GLU B 1 82  ? 7.533   -47.895 9.003   1.00 75.29  ? 82  GLU B CA  1 
ATOM   4223  C C   . GLU B 1 82  ? 6.338   -48.433 9.793   1.00 65.35  ? 82  GLU B C   1 
ATOM   4224  O O   . GLU B 1 82  ? 5.491   -47.659 10.230  1.00 50.42  ? 82  GLU B O   1 
ATOM   4225  C CB  . GLU B 1 82  ? 8.469   -47.070 9.897   1.00 84.33  ? 82  GLU B CB  1 
ATOM   4226  C CG  . GLU B 1 82  ? 9.487   -47.929 10.657  1.00 96.90  ? 82  GLU B CG  1 
ATOM   4227  C CD  . GLU B 1 82  ? 10.030  -47.402 11.986  1.00 106.47 ? 82  GLU B CD  1 
ATOM   4228  O OE1 . GLU B 1 82  ? 10.937  -48.061 12.554  1.00 100.48 ? 82  GLU B OE1 1 
ATOM   4229  O OE2 . GLU B 1 82  ? 9.540   -46.355 12.480  1.00 104.01 ? 82  GLU B OE2 1 
ATOM   4230  N N   . GLY B 1 83  ? 6.251   -49.768 9.921   1.00 57.06  ? 83  GLY B N   1 
ATOM   4231  C CA  . GLY B 1 83  ? 5.152   -50.399 10.631  1.00 51.76  ? 83  GLY B CA  1 
ATOM   4232  C C   . GLY B 1 83  ? 3.981   -50.648 9.702   1.00 51.96  ? 83  GLY B C   1 
ATOM   4233  O O   . GLY B 1 83  ? 3.040   -51.355 10.043  1.00 52.20  ? 83  GLY B O   1 
ATOM   4234  N N   . GLY B 1 84  ? 4.092   -50.115 8.479   1.00 63.64  ? 84  GLY B N   1 
ATOM   4235  C CA  . GLY B 1 84  ? 3.018   -50.201 7.510   1.00 53.68  ? 84  GLY B CA  1 
ATOM   4236  C C   . GLY B 1 84  ? 2.962   -51.543 6.797   1.00 52.98  ? 84  GLY B C   1 
ATOM   4237  O O   . GLY B 1 84  ? 3.948   -52.256 6.734   1.00 53.04  ? 84  GLY B O   1 
ATOM   4238  N N   . PHE B 1 85  ? 1.799   -51.849 6.213   1.00 63.34  ? 85  PHE B N   1 
ATOM   4239  C CA  . PHE B 1 85  ? 1.662   -52.937 5.259   1.00 63.41  ? 85  PHE B CA  1 
ATOM   4240  C C   . PHE B 1 85  ? 1.505   -52.425 3.817   1.00 59.31  ? 85  PHE B C   1 
ATOM   4241  O O   . PHE B 1 85  ? 2.102   -52.957 2.882   1.00 58.08  ? 85  PHE B O   1 
ATOM   4242  C CB  . PHE B 1 85  ? 0.455   -53.798 5.639   1.00 63.77  ? 85  PHE B CB  1 
ATOM   4243  C CG  . PHE B 1 85  ? 0.329   -55.009 4.754   1.00 65.15  ? 85  PHE B CG  1 
ATOM   4244  C CD1 . PHE B 1 85  ? 1.245   -56.059 4.859   1.00 62.55  ? 85  PHE B CD1 1 
ATOM   4245  C CD2 . PHE B 1 85  ? -0.624  -55.052 3.746   1.00 61.76  ? 85  PHE B CD2 1 
ATOM   4246  C CE1 . PHE B 1 85  ? 1.156   -57.162 4.022   1.00 65.45  ? 85  PHE B CE1 1 
ATOM   4247  C CE2 . PHE B 1 85  ? -0.696  -56.149 2.897   1.00 63.45  ? 85  PHE B CE2 1 
ATOM   4248  C CZ  . PHE B 1 85  ? 0.184   -57.206 3.039   1.00 61.19  ? 85  PHE B CZ  1 
ATOM   4249  N N   . GLU B 1 86  ? 0.673   -51.394 3.620   1.00 66.28  ? 86  GLU B N   1 
ATOM   4250  C CA  . GLU B 1 86  ? 0.212   -50.997 2.294   1.00 54.97  ? 86  GLU B CA  1 
ATOM   4251  C C   . GLU B 1 86  ? 1.334   -50.360 1.484   1.00 45.44  ? 86  GLU B C   1 
ATOM   4252  O O   . GLU B 1 86  ? 2.224   -49.726 2.017   1.00 42.34  ? 86  GLU B O   1 
ATOM   4253  C CB  . GLU B 1 86  ? -0.964  -50.031 2.401   1.00 60.12  ? 86  GLU B CB  1 
ATOM   4254  C CG  . GLU B 1 86  ? -2.193  -50.640 3.055   1.00 61.38  ? 86  GLU B CG  1 
ATOM   4255  C CD  . GLU B 1 86  ? -2.685  -51.905 2.386   1.00 63.54  ? 86  GLU B CD  1 
ATOM   4256  O OE1 . GLU B 1 86  ? -3.385  -52.666 3.076   1.00 68.39  ? 86  GLU B OE1 1 
ATOM   4257  O OE2 . GLU B 1 86  ? -2.371  -52.110 1.173   1.00 58.45  ? 86  GLU B OE2 1 
ATOM   4258  N N   . PRO B 1 87  ? 1.360   -50.566 0.152   1.00 47.22  ? 87  PRO B N   1 
ATOM   4259  C CA  . PRO B 1 87  ? 2.412   -49.968 -0.676  1.00 45.16  ? 87  PRO B CA  1 
ATOM   4260  C C   . PRO B 1 87  ? 2.347   -48.426 -0.706  1.00 47.55  ? 87  PRO B C   1 
ATOM   4261  O O   . PRO B 1 87  ? 1.264   -47.847 -0.782  1.00 38.07  ? 87  PRO B O   1 
ATOM   4262  C CB  . PRO B 1 87  ? 2.146   -50.605 -2.051  1.00 47.10  ? 87  PRO B CB  1 
ATOM   4263  C CG  . PRO B 1 87  ? 0.686   -51.092 -2.024  1.00 43.64  ? 87  PRO B CG  1 
ATOM   4264  C CD  . PRO B 1 87  ? 0.371   -51.367 -0.584  1.00 40.26  ? 87  PRO B CD  1 
ATOM   4265  N N   . LEU B 1 88  ? 3.518   -47.765 -0.617  1.00 45.24  ? 88  LEU B N   1 
ATOM   4266  C CA  . LEU B 1 88  ? 3.611   -46.314 -0.734  1.00 46.53  ? 88  LEU B CA  1 
ATOM   4267  C C   . LEU B 1 88  ? 3.452   -45.922 -2.197  1.00 51.77  ? 88  LEU B C   1 
ATOM   4268  O O   . LEU B 1 88  ? 4.243   -46.366 -3.037  1.00 44.54  ? 88  LEU B O   1 
ATOM   4269  C CB  . LEU B 1 88  ? 4.939   -45.786 -0.183  1.00 43.38  ? 88  LEU B CB  1 
ATOM   4270  C CG  . LEU B 1 88  ? 5.105   -45.862 1.339   1.00 48.31  ? 88  LEU B CG  1 
ATOM   4271  C CD1 . LEU B 1 88  ? 6.378   -45.156 1.792   1.00 57.09  ? 88  LEU B CD1 1 
ATOM   4272  C CD2 . LEU B 1 88  ? 3.907   -45.285 2.066   1.00 45.06  ? 88  LEU B CD2 1 
ATOM   4273  N N   . PRO B 1 89  ? 2.435   -45.072 -2.517  1.00 54.08  ? 89  PRO B N   1 
ATOM   4274  C CA  . PRO B 1 89  ? 2.218   -44.591 -3.883  1.00 48.06  ? 89  PRO B CA  1 
ATOM   4275  C C   . PRO B 1 89  ? 3.522   -44.060 -4.477  1.00 43.48  ? 89  PRO B C   1 
ATOM   4276  O O   . PRO B 1 89  ? 3.739   -44.151 -5.674  1.00 46.84  ? 89  PRO B O   1 
ATOM   4277  C CB  . PRO B 1 89  ? 1.149   -43.510 -3.700  1.00 51.18  ? 89  PRO B CB  1 
ATOM   4278  C CG  . PRO B 1 89  ? 0.391   -43.935 -2.473  1.00 56.43  ? 89  PRO B CG  1 
ATOM   4279  C CD  . PRO B 1 89  ? 1.443   -44.533 -1.570  1.00 55.56  ? 89  PRO B CD  1 
ATOM   4280  N N   . GLU B 1 90  ? 4.418   -43.571 -3.612  1.00 45.81  ? 90  GLU B N   1 
ATOM   4281  C CA  . GLU B 1 90  ? 5.696   -43.029 -4.028  1.00 48.29  ? 90  GLU B CA  1 
ATOM   4282  C C   . GLU B 1 90  ? 6.506   -44.068 -4.797  1.00 48.09  ? 90  GLU B C   1 
ATOM   4283  O O   . GLU B 1 90  ? 7.236   -43.707 -5.714  1.00 41.16  ? 90  GLU B O   1 
ATOM   4284  C CB  . GLU B 1 90  ? 6.506   -42.556 -2.817  1.00 53.04  ? 90  GLU B CB  1 
ATOM   4285  C CG  . GLU B 1 90  ? 5.978   -41.292 -2.173  1.00 57.97  ? 90  GLU B CG  1 
ATOM   4286  C CD  . GLU B 1 90  ? 5.184   -41.464 -0.891  1.00 53.21  ? 90  GLU B CD  1 
ATOM   4287  O OE1 . GLU B 1 90  ? 5.499   -40.725 0.046   1.00 59.34  ? 90  GLU B OE1 1 
ATOM   4288  O OE2 . GLU B 1 90  ? 4.282   -42.338 -0.824  1.00 48.60  ? 90  GLU B OE2 1 
ATOM   4289  N N   . GLY B 1 91  ? 6.438   -45.325 -4.337  1.00 50.66  ? 91  GLY B N   1 
ATOM   4290  C CA  . GLY B 1 91  ? 7.204   -46.421 -4.908  1.00 47.74  ? 91  GLY B CA  1 
ATOM   4291  C C   . GLY B 1 91  ? 6.624   -46.834 -6.256  1.00 50.61  ? 91  GLY B C   1 
ATOM   4292  O O   . GLY B 1 91  ? 7.382   -46.990 -7.217  1.00 47.05  ? 91  GLY B O   1 
ATOM   4293  N N   . LEU B 1 92  ? 5.287   -46.993 -6.295  1.00 43.00  ? 92  LEU B N   1 
ATOM   4294  C CA  . LEU B 1 92  ? 4.553   -47.174 -7.543  1.00 46.10  ? 92  LEU B CA  1 
ATOM   4295  C C   . LEU B 1 92  ? 4.947   -46.125 -8.592  1.00 48.50  ? 92  LEU B C   1 
ATOM   4296  O O   . LEU B 1 92  ? 5.195   -46.435 -9.752  1.00 48.11  ? 92  LEU B O   1 
ATOM   4297  C CB  . LEU B 1 92  ? 3.054   -47.111 -7.273  1.00 42.79  ? 92  LEU B CB  1 
ATOM   4298  C CG  . LEU B 1 92  ? 2.197   -47.212 -8.522  1.00 46.90  ? 92  LEU B CG  1 
ATOM   4299  C CD1 . LEU B 1 92  ? 2.494   -48.504 -9.260  1.00 45.18  ? 92  LEU B CD1 1 
ATOM   4300  C CD2 . LEU B 1 92  ? 0.731   -47.161 -8.169  1.00 52.42  ? 92  LEU B CD2 1 
ATOM   4301  N N   . TRP B 1 93  ? 5.079   -44.877 -8.162  1.00 45.51  ? 93  TRP B N   1 
ATOM   4302  C CA  . TRP B 1 93  ? 5.403   -43.828 -9.089  1.00 45.49  ? 93  TRP B CA  1 
ATOM   4303  C C   . TRP B 1 93  ? 6.784   -44.051 -9.710  1.00 49.43  ? 93  TRP B C   1 
ATOM   4304  O O   . TRP B 1 93  ? 6.929   -43.913 -10.924 1.00 46.47  ? 93  TRP B O   1 
ATOM   4305  C CB  . TRP B 1 93  ? 5.296   -42.488 -8.368  1.00 45.29  ? 93  TRP B CB  1 
ATOM   4306  C CG  . TRP B 1 93  ? 5.148   -41.367 -9.327  1.00 40.46  ? 93  TRP B CG  1 
ATOM   4307  C CD1 . TRP B 1 93  ? 4.161   -41.212 -10.249 1.00 36.95  ? 93  TRP B CD1 1 
ATOM   4308  C CD2 . TRP B 1 93  ? 6.030   -40.247 -9.463  1.00 41.23  ? 93  TRP B CD2 1 
ATOM   4309  N NE1 . TRP B 1 93  ? 4.364   -40.054 -10.943 1.00 41.61  ? 93  TRP B NE1 1 
ATOM   4310  C CE2 . TRP B 1 93  ? 5.513   -39.455 -10.495 1.00 41.25  ? 93  TRP B CE2 1 
ATOM   4311  C CE3 . TRP B 1 93  ? 7.208   -39.860 -8.832  1.00 41.70  ? 93  TRP B CE3 1 
ATOM   4312  C CZ2 . TRP B 1 93  ? 6.132   -38.275 -10.895 1.00 47.80  ? 93  TRP B CZ2 1 
ATOM   4313  C CZ3 . TRP B 1 93  ? 7.803   -38.689 -9.211  1.00 41.22  ? 93  TRP B CZ3 1 
ATOM   4314  C CH2 . TRP B 1 93  ? 7.284   -37.919 -10.241 1.00 44.79  ? 93  TRP B CH2 1 
ATOM   4315  N N   . TYR B 1 94  ? 7.788   -44.391 -8.881  1.00 51.93  ? 94  TYR B N   1 
ATOM   4316  C CA  . TYR B 1 94  ? 9.091   -44.873 -9.347  1.00 52.03  ? 94  TYR B CA  1 
ATOM   4317  C C   . TYR B 1 94  ? 8.909   -45.988 -10.380 1.00 50.92  ? 94  TYR B C   1 
ATOM   4318  O O   . TYR B 1 94  ? 9.533   -45.944 -11.447 1.00 49.17  ? 94  TYR B O   1 
ATOM   4319  C CB  . TYR B 1 94  ? 9.976   -45.390 -8.198  1.00 52.71  ? 94  TYR B CB  1 
ATOM   4320  C CG  . TYR B 1 94  ? 11.415  -45.644 -8.578  1.00 53.92  ? 94  TYR B CG  1 
ATOM   4321  C CD1 . TYR B 1 94  ? 11.796  -46.788 -9.275  1.00 55.02  ? 94  TYR B CD1 1 
ATOM   4322  C CD2 . TYR B 1 94  ? 12.405  -44.710 -8.285  1.00 59.21  ? 94  TYR B CD2 1 
ATOM   4323  C CE1 . TYR B 1 94  ? 13.119  -46.995 -9.662  1.00 50.23  ? 94  TYR B CE1 1 
ATOM   4324  C CE2 . TYR B 1 94  ? 13.731  -44.903 -8.660  1.00 53.50  ? 94  TYR B CE2 1 
ATOM   4325  C CZ  . TYR B 1 94  ? 14.091  -46.057 -9.341  1.00 52.38  ? 94  TYR B CZ  1 
ATOM   4326  O OH  . TYR B 1 94  ? 15.398  -46.221 -9.707  1.00 51.46  ? 94  TYR B OH  1 
ATOM   4327  N N   . LEU B 1 95  ? 8.031   -46.958 -10.071 1.00 40.97  ? 95  LEU B N   1 
ATOM   4328  C CA  . LEU B 1 95  ? 7.793   -48.058 -10.973 1.00 41.31  ? 95  LEU B CA  1 
ATOM   4329  C C   . LEU B 1 95  ? 7.194   -47.588 -12.303 1.00 49.19  ? 95  LEU B C   1 
ATOM   4330  O O   . LEU B 1 95  ? 7.645   -48.000 -13.377 1.00 44.31  ? 95  LEU B O   1 
ATOM   4331  C CB  . LEU B 1 95  ? 6.882   -49.079 -10.305 1.00 45.79  ? 95  LEU B CB  1 
ATOM   4332  C CG  . LEU B 1 95  ? 6.428   -50.212 -11.224 1.00 46.77  ? 95  LEU B CG  1 
ATOM   4333  C CD1 . LEU B 1 95  ? 7.638   -50.960 -11.821 1.00 52.50  ? 95  LEU B CD1 1 
ATOM   4334  C CD2 . LEU B 1 95  ? 5.527   -51.145 -10.457 1.00 45.31  ? 95  LEU B CD2 1 
ATOM   4335  N N   . LEU B 1 96  ? 6.148   -46.756 -12.249 1.00 50.26  ? 96  LEU B N   1 
ATOM   4336  C CA  . LEU B 1 96  ? 5.435   -46.380 -13.458 1.00 41.78  ? 96  LEU B CA  1 
ATOM   4337  C C   . LEU B 1 96  ? 6.380   -45.653 -14.414 1.00 44.46  ? 96  LEU B C   1 
ATOM   4338  O O   . LEU B 1 96  ? 6.378   -45.876 -15.619 1.00 45.73  ? 96  LEU B O   1 
ATOM   4339  C CB  . LEU B 1 96  ? 4.255   -45.500 -13.053 1.00 47.61  ? 96  LEU B CB  1 
ATOM   4340  C CG  . LEU B 1 96  ? 3.117   -46.196 -12.320 1.00 41.04  ? 96  LEU B CG  1 
ATOM   4341  C CD1 . LEU B 1 96  ? 1.901   -45.297 -12.261 1.00 47.44  ? 96  LEU B CD1 1 
ATOM   4342  C CD2 . LEU B 1 96  ? 2.752   -47.502 -12.983 1.00 42.82  ? 96  LEU B CD2 1 
ATOM   4343  N N   . LEU B 1 97  ? 7.238   -44.802 -13.871 1.00 45.92  ? 97  LEU B N   1 
ATOM   4344  C CA  . LEU B 1 97  ? 8.160   -44.067 -14.711 1.00 51.77  ? 97  LEU B CA  1 
ATOM   4345  C C   . LEU B 1 97  ? 9.300   -44.938 -15.278 1.00 54.21  ? 97  LEU B C   1 
ATOM   4346  O O   . LEU B 1 97  ? 9.654   -44.783 -16.449 1.00 52.79  ? 97  LEU B O   1 
ATOM   4347  C CB  . LEU B 1 97  ? 8.686   -42.892 -13.890 1.00 49.28  ? 97  LEU B CB  1 
ATOM   4348  C CG  . LEU B 1 97  ? 7.746   -41.692 -13.856 1.00 51.41  ? 97  LEU B CG  1 
ATOM   4349  C CD1 . LEU B 1 97  ? 8.117   -40.755 -12.718 1.00 53.40  ? 97  LEU B CD1 1 
ATOM   4350  C CD2 . LEU B 1 97  ? 7.789   -40.945 -15.176 1.00 55.84  ? 97  LEU B CD2 1 
ATOM   4351  N N   . THR B 1 98  ? 9.930   -45.794 -14.461 1.00 47.08  ? 98  THR B N   1 
ATOM   4352  C CA  . THR B 1 98  ? 11.172  -46.448 -14.865 1.00 54.21  ? 98  THR B CA  1 
ATOM   4353  C C   . THR B 1 98  ? 10.932  -47.870 -15.369 1.00 52.62  ? 98  THR B C   1 
ATOM   4354  O O   . THR B 1 98  ? 11.745  -48.384 -16.129 1.00 58.41  ? 98  THR B O   1 
ATOM   4355  C CB  . THR B 1 98  ? 12.212  -46.539 -13.740 1.00 51.22  ? 98  THR B CB  1 
ATOM   4356  O OG1 . THR B 1 98  ? 11.692  -47.378 -12.698 1.00 44.63  ? 98  THR B OG1 1 
ATOM   4357  C CG2 . THR B 1 98  ? 12.587  -45.158 -13.249 1.00 52.10  ? 98  THR B CG2 1 
ATOM   4358  N N   . GLY B 1 99  ? 9.859   -48.504 -14.897 1.00 47.01  ? 99  GLY B N   1 
ATOM   4359  C CA  . GLY B 1 99  ? 9.577   -49.885 -15.222 1.00 46.14  ? 99  GLY B CA  1 
ATOM   4360  C C   . GLY B 1 99  ? 10.326  -50.860 -14.325 1.00 52.33  ? 99  GLY B C   1 
ATOM   4361  O O   . GLY B 1 99  ? 10.098  -52.071 -14.450 1.00 63.16  ? 99  GLY B O   1 
ATOM   4362  N N   . GLU B 1 100 ? 11.209  -50.325 -13.457 1.00 54.15  ? 100 GLU B N   1 
ATOM   4363  C CA  . GLU B 1 100 ? 11.979  -51.073 -12.457 1.00 56.09  ? 100 GLU B CA  1 
ATOM   4364  C C   . GLU B 1 100 ? 11.371  -50.867 -11.069 1.00 59.79  ? 100 GLU B C   1 
ATOM   4365  O O   . GLU B 1 100 ? 10.827  -49.794 -10.790 1.00 67.26  ? 100 GLU B O   1 
ATOM   4366  C CB  . GLU B 1 100 ? 13.427  -50.567 -12.337 1.00 54.73  ? 100 GLU B CB  1 
ATOM   4367  C CG  . GLU B 1 100 ? 14.293  -50.793 -13.575 1.00 60.68  ? 100 GLU B CG  1 
ATOM   4368  C CD  . GLU B 1 100 ? 15.488  -49.851 -13.740 1.00 70.96  ? 100 GLU B CD  1 
ATOM   4369  O OE1 . GLU B 1 100 ? 16.086  -49.875 -14.846 1.00 58.73  ? 100 GLU B OE1 1 
ATOM   4370  O OE2 . GLU B 1 100 ? 15.828  -49.078 -12.772 1.00 72.21  ? 100 GLU B OE2 1 
ATOM   4371  N N   . LEU B 1 101 ? 11.521  -51.869 -10.192 1.00 56.73  ? 101 LEU B N   1 
ATOM   4372  C CA  . LEU B 1 101 ? 11.107  -51.749 -8.795  1.00 58.81  ? 101 LEU B CA  1 
ATOM   4373  C C   . LEU B 1 101 ? 12.098  -50.885 -8.021  1.00 64.65  ? 101 LEU B C   1 
ATOM   4374  O O   . LEU B 1 101 ? 13.318  -51.029 -8.176  1.00 54.31  ? 101 LEU B O   1 
ATOM   4375  C CB  . LEU B 1 101 ? 11.009  -53.125 -8.149  1.00 51.61  ? 101 LEU B CB  1 
ATOM   4376  C CG  . LEU B 1 101 ? 9.956   -54.016 -8.792  1.00 56.68  ? 101 LEU B CG  1 
ATOM   4377  C CD1 . LEU B 1 101 ? 10.266  -55.495 -8.562  1.00 53.59  ? 101 LEU B CD1 1 
ATOM   4378  C CD2 . LEU B 1 101 ? 8.573   -53.646 -8.274  1.00 54.16  ? 101 LEU B CD2 1 
ATOM   4379  N N   . PRO B 1 102 ? 11.592  -49.983 -7.145  1.00 62.21  ? 102 PRO B N   1 
ATOM   4380  C CA  . PRO B 1 102 ? 12.453  -49.091 -6.357  1.00 60.47  ? 102 PRO B CA  1 
ATOM   4381  C C   . PRO B 1 102 ? 13.108  -49.770 -5.152  1.00 49.60  ? 102 PRO B C   1 
ATOM   4382  O O   . PRO B 1 102 ? 12.557  -50.728 -4.608  1.00 47.38  ? 102 PRO B O   1 
ATOM   4383  C CB  . PRO B 1 102 ? 11.444  -48.039 -5.861  1.00 58.58  ? 102 PRO B CB  1 
ATOM   4384  C CG  . PRO B 1 102 ? 10.166  -48.843 -5.661  1.00 56.68  ? 102 PRO B CG  1 
ATOM   4385  C CD  . PRO B 1 102 ? 10.163  -49.842 -6.803  1.00 60.32  ? 102 PRO B CD  1 
ATOM   4386  N N   . THR B 1 103 ? 14.254  -49.227 -4.718  1.00 59.98  ? 103 THR B N   1 
ATOM   4387  C CA  . THR B 1 103 ? 14.849  -49.557 -3.421  1.00 60.99  ? 103 THR B CA  1 
ATOM   4388  C C   . THR B 1 103 ? 14.164  -48.718 -2.349  1.00 59.42  ? 103 THR B C   1 
ATOM   4389  O O   . THR B 1 103 ? 13.549  -47.686 -2.666  1.00 60.11  ? 103 THR B O   1 
ATOM   4390  C CB  . THR B 1 103 ? 16.365  -49.276 -3.369  1.00 68.85  ? 103 THR B CB  1 
ATOM   4391  O OG1 . THR B 1 103 ? 16.619  -47.877 -3.587  1.00 59.46  ? 103 THR B OG1 1 
ATOM   4392  C CG2 . THR B 1 103 ? 17.153  -50.092 -4.379  1.00 70.32  ? 103 THR B CG2 1 
ATOM   4393  N N   . GLU B 1 104 ? 14.297  -49.161 -1.092  1.00 57.57  ? 104 GLU B N   1 
ATOM   4394  C CA  . GLU B 1 104 ? 13.805  -48.426 0.062   1.00 57.32  ? 104 GLU B CA  1 
ATOM   4395  C C   . GLU B 1 104 ? 14.357  -47.001 -0.009  1.00 61.76  ? 104 GLU B C   1 
ATOM   4396  O O   . GLU B 1 104 ? 13.613  -46.040 0.163   1.00 58.16  ? 104 GLU B O   1 
ATOM   4397  C CB  . GLU B 1 104 ? 14.188  -49.164 1.348   1.00 58.32  ? 104 GLU B CB  1 
ATOM   4398  C CG  . GLU B 1 104 ? 13.374  -50.433 1.618   1.00 61.12  ? 104 GLU B CG  1 
ATOM   4399  C CD  . GLU B 1 104 ? 12.077  -50.283 2.406   1.00 67.46  ? 104 GLU B CD  1 
ATOM   4400  O OE1 . GLU B 1 104 ? 11.287  -51.286 2.494   1.00 62.74  ? 104 GLU B OE1 1 
ATOM   4401  O OE2 . GLU B 1 104 ? 11.844  -49.170 2.947   1.00 64.03  ? 104 GLU B OE2 1 
ATOM   4402  N N   . GLU B 1 105 ? 15.657  -46.890 -0.319  1.00 66.62  ? 105 GLU B N   1 
ATOM   4403  C CA  . GLU B 1 105 ? 16.342  -45.626 -0.542  1.00 69.83  ? 105 GLU B CA  1 
ATOM   4404  C C   . GLU B 1 105 ? 15.682  -44.812 -1.668  1.00 69.75  ? 105 GLU B C   1 
ATOM   4405  O O   . GLU B 1 105 ? 15.551  -43.586 -1.566  1.00 65.45  ? 105 GLU B O   1 
ATOM   4406  C CB  . GLU B 1 105 ? 17.801  -45.933 -0.863  1.00 77.83  ? 105 GLU B CB  1 
ATOM   4407  C CG  . GLU B 1 105 ? 18.727  -44.737 -0.781  1.00 90.78  ? 105 GLU B CG  1 
ATOM   4408  C CD  . GLU B 1 105 ? 19.993  -44.973 -1.589  1.00 112.67 ? 105 GLU B CD  1 
ATOM   4409  O OE1 . GLU B 1 105 ? 20.920  -45.646 -1.076  1.00 105.64 ? 105 GLU B OE1 1 
ATOM   4410  O OE2 . GLU B 1 105 ? 20.032  -44.517 -2.752  1.00 132.61 ? 105 GLU B OE2 1 
ATOM   4411  N N   . ASP B 1 106 ? 15.285  -45.473 -2.765  1.00 72.84  ? 106 ASP B N   1 
ATOM   4412  C CA  . ASP B 1 106 ? 14.635  -44.791 -3.886  1.00 76.34  ? 106 ASP B CA  1 
ATOM   4413  C C   . ASP B 1 106 ? 13.324  -44.126 -3.433  1.00 66.16  ? 106 ASP B C   1 
ATOM   4414  O O   . ASP B 1 106 ? 13.030  -42.986 -3.812  1.00 57.96  ? 106 ASP B O   1 
ATOM   4415  C CB  . ASP B 1 106 ? 14.401  -45.743 -5.069  1.00 72.53  ? 106 ASP B CB  1 
ATOM   4416  C CG  . ASP B 1 106 ? 15.673  -46.211 -5.764  1.00 72.94  ? 106 ASP B CG  1 
ATOM   4417  O OD1 . ASP B 1 106 ? 16.681  -45.491 -5.670  1.00 74.37  ? 106 ASP B OD1 1 
ATOM   4418  O OD2 . ASP B 1 106 ? 15.650  -47.307 -6.383  1.00 65.40  ? 106 ASP B OD2 1 
ATOM   4419  N N   . VAL B 1 107 ? 12.556  -44.845 -2.605  1.00 52.61  ? 107 VAL B N   1 
ATOM   4420  C CA  . VAL B 1 107 ? 11.276  -44.371 -2.120  1.00 53.96  ? 107 VAL B CA  1 
ATOM   4421  C C   . VAL B 1 107 ? 11.493  -43.193 -1.171  1.00 59.33  ? 107 VAL B C   1 
ATOM   4422  O O   . VAL B 1 107 ? 10.808  -42.178 -1.288  1.00 61.10  ? 107 VAL B O   1 
ATOM   4423  C CB  . VAL B 1 107 ? 10.490  -45.512 -1.456  1.00 49.06  ? 107 VAL B CB  1 
ATOM   4424  C CG1 . VAL B 1 107 ? 9.271   -44.999 -0.690  1.00 56.26  ? 107 VAL B CG1 1 
ATOM   4425  C CG2 . VAL B 1 107 ? 10.093  -46.533 -2.497  1.00 50.14  ? 107 VAL B CG2 1 
ATOM   4426  N N   . LYS B 1 108 ? 12.445  -43.344 -0.243  1.00 61.04  ? 108 LYS B N   1 
ATOM   4427  C CA  . LYS B 1 108 ? 12.762  -42.304 0.717   1.00 66.88  ? 108 LYS B CA  1 
ATOM   4428  C C   . LYS B 1 108 ? 13.138  -41.012 -0.006  1.00 60.83  ? 108 LYS B C   1 
ATOM   4429  O O   . LYS B 1 108 ? 12.734  -39.935 0.439   1.00 58.07  ? 108 LYS B O   1 
ATOM   4430  C CB  . LYS B 1 108 ? 13.910  -42.714 1.649   1.00 75.28  ? 108 LYS B CB  1 
ATOM   4431  C CG  . LYS B 1 108 ? 13.522  -43.410 2.949   1.00 88.73  ? 108 LYS B CG  1 
ATOM   4432  C CD  . LYS B 1 108 ? 14.590  -43.228 4.042   1.00 103.53 ? 108 LYS B CD  1 
ATOM   4433  C CE  . LYS B 1 108 ? 14.420  -44.124 5.255   1.00 111.70 ? 108 LYS B CE  1 
ATOM   4434  N NZ  . LYS B 1 108 ? 14.667  -45.555 4.941   1.00 109.99 ? 108 LYS B NZ  1 
ATOM   4435  N N   . GLU B 1 109 ? 13.943  -41.107 -1.078  1.00 57.84  ? 109 GLU B N   1 
ATOM   4436  C CA  . GLU B 1 109 ? 14.318  -39.918 -1.841  1.00 65.32  ? 109 GLU B CA  1 
ATOM   4437  C C   . GLU B 1 109 ? 13.062  -39.201 -2.359  1.00 64.14  ? 109 GLU B C   1 
ATOM   4438  O O   . GLU B 1 109 ? 13.009  -37.971 -2.378  1.00 52.57  ? 109 GLU B O   1 
ATOM   4439  C CB  . GLU B 1 109 ? 15.227  -40.251 -3.029  1.00 70.84  ? 109 GLU B CB  1 
ATOM   4440  C CG  . GLU B 1 109 ? 16.721  -40.200 -2.734  1.00 79.30  ? 109 GLU B CG  1 
ATOM   4441  C CD  . GLU B 1 109 ? 17.610  -40.620 -3.906  1.00 86.01  ? 109 GLU B CD  1 
ATOM   4442  O OE1 . GLU B 1 109 ? 18.824  -40.880 -3.667  1.00 68.98  ? 109 GLU B OE1 1 
ATOM   4443  O OE2 . GLU B 1 109 ? 17.086  -40.715 -5.065  1.00 82.75  ? 109 GLU B OE2 1 
ATOM   4444  N N   . ILE B 1 110 ? 12.054  -39.973 -2.791  1.00 52.95  ? 110 ILE B N   1 
ATOM   4445  C CA  . ILE B 1 110 ? 10.867  -39.415 -3.411  1.00 54.70  ? 110 ILE B CA  1 
ATOM   4446  C C   . ILE B 1 110 ? 9.947   -38.838 -2.332  1.00 61.62  ? 110 ILE B C   1 
ATOM   4447  O O   . ILE B 1 110 ? 9.382   -37.753 -2.522  1.00 56.16  ? 110 ILE B O   1 
ATOM   4448  C CB  . ILE B 1 110 ? 10.184  -40.463 -4.302  1.00 48.94  ? 110 ILE B CB  1 
ATOM   4449  C CG1 . ILE B 1 110 ? 10.944  -40.629 -5.616  1.00 56.49  ? 110 ILE B CG1 1 
ATOM   4450  C CG2 . ILE B 1 110 ? 8.727   -40.127 -4.557  1.00 49.13  ? 110 ILE B CG2 1 
ATOM   4451  C CD1 . ILE B 1 110 ? 10.498  -41.858 -6.412  1.00 61.30  ? 110 ILE B CD1 1 
ATOM   4452  N N   . SER B 1 111 ? 9.809   -39.571 -1.221  1.00 57.15  ? 111 SER B N   1 
ATOM   4453  C CA  . SER B 1 111 ? 9.115   -39.071 -0.047  1.00 63.01  ? 111 SER B CA  1 
ATOM   4454  C C   . SER B 1 111 ? 9.682   -37.721 0.410   1.00 57.60  ? 111 SER B C   1 
ATOM   4455  O O   . SER B 1 111 ? 8.933   -36.804 0.712   1.00 64.77  ? 111 SER B O   1 
ATOM   4456  C CB  . SER B 1 111 ? 9.115   -40.110 1.030   1.00 58.55  ? 111 SER B CB  1 
ATOM   4457  O OG  . SER B 1 111 ? 8.147   -41.112 0.716   1.00 59.40  ? 111 SER B OG  1 
ATOM   4458  N N   . ALA B 1 112 ? 10.997  -37.551 0.388   1.00 54.35  ? 112 ALA B N   1 
ATOM   4459  C CA  . ALA B 1 112 ? 11.600  -36.321 0.888   1.00 64.13  ? 112 ALA B CA  1 
ATOM   4460  C C   . ALA B 1 112 ? 11.318  -35.176 -0.078  1.00 65.38  ? 112 ALA B C   1 
ATOM   4461  O O   . ALA B 1 112 ? 11.102  -34.034 0.307   1.00 65.04  ? 112 ALA B O   1 
ATOM   4462  C CB  . ALA B 1 112 ? 13.102  -36.480 1.047   1.00 61.26  ? 112 ALA B CB  1 
ATOM   4463  N N   . GLU B 1 113 ? 11.409  -35.502 -1.362  1.00 68.88  ? 113 GLU B N   1 
ATOM   4464  C CA  . GLU B 1 113 ? 11.135  -34.559 -2.421  1.00 62.15  ? 113 GLU B CA  1 
ATOM   4465  C C   . GLU B 1 113 ? 9.679   -34.097 -2.272  1.00 55.57  ? 113 GLU B C   1 
ATOM   4466  O O   . GLU B 1 113 ? 9.391   -32.904 -2.405  1.00 50.61  ? 113 GLU B O   1 
ATOM   4467  C CB  . GLU B 1 113 ? 11.535  -35.259 -3.720  1.00 67.47  ? 113 GLU B CB  1 
ATOM   4468  C CG  . GLU B 1 113 ? 12.019  -34.329 -4.797  1.00 80.50  ? 113 GLU B CG  1 
ATOM   4469  C CD  . GLU B 1 113 ? 13.392  -33.704 -4.610  1.00 78.49  ? 113 GLU B CD  1 
ATOM   4470  O OE1 . GLU B 1 113 ? 13.429  -32.486 -4.323  1.00 75.09  ? 113 GLU B OE1 1 
ATOM   4471  O OE2 . GLU B 1 113 ? 14.412  -34.401 -4.850  1.00 73.60  ? 113 GLU B OE2 1 
ATOM   4472  N N   . PHE B 1 114 ? 8.773   -35.031 -1.928  1.00 48.25  ? 114 PHE B N   1 
ATOM   4473  C CA  . PHE B 1 114 ? 7.355   -34.727 -1.841  1.00 56.69  ? 114 PHE B CA  1 
ATOM   4474  C C   . PHE B 1 114 ? 7.079   -33.847 -0.629  1.00 62.86  ? 114 PHE B C   1 
ATOM   4475  O O   . PHE B 1 114 ? 6.382   -32.835 -0.767  1.00 58.89  ? 114 PHE B O   1 
ATOM   4476  C CB  . PHE B 1 114 ? 6.468   -35.980 -1.819  1.00 51.67  ? 114 PHE B CB  1 
ATOM   4477  C CG  . PHE B 1 114 ? 6.168   -36.599 -3.169  1.00 53.27  ? 114 PHE B CG  1 
ATOM   4478  C CD1 . PHE B 1 114 ? 6.562   -35.997 -4.363  1.00 52.35  ? 114 PHE B CD1 1 
ATOM   4479  C CD2 . PHE B 1 114 ? 5.514   -37.823 -3.249  1.00 53.92  ? 114 PHE B CD2 1 
ATOM   4480  C CE1 . PHE B 1 114 ? 6.298   -36.603 -5.586  1.00 57.63  ? 114 PHE B CE1 1 
ATOM   4481  C CE2 . PHE B 1 114 ? 5.246   -38.424 -4.475  1.00 53.35  ? 114 PHE B CE2 1 
ATOM   4482  C CZ  . PHE B 1 114 ? 5.656   -37.826 -5.645  1.00 51.23  ? 114 PHE B CZ  1 
ATOM   4483  N N   . THR B 1 115 ? 7.628   -34.256 0.525   1.00 65.88  ? 115 THR B N   1 
ATOM   4484  C CA  . THR B 1 115 ? 7.497   -33.523 1.782   1.00 76.16  ? 115 THR B CA  1 
ATOM   4485  C C   . THR B 1 115 ? 8.089   -32.110 1.653   1.00 66.51  ? 115 THR B C   1 
ATOM   4486  O O   . THR B 1 115 ? 7.423   -31.122 1.924   1.00 57.66  ? 115 THR B O   1 
ATOM   4487  C CB  . THR B 1 115 ? 8.097   -34.331 2.944   1.00 76.69  ? 115 THR B CB  1 
ATOM   4488  O OG1 . THR B 1 115 ? 7.095   -35.211 3.449   1.00 63.68  ? 115 THR B OG1 1 
ATOM   4489  C CG2 . THR B 1 115 ? 8.592   -33.466 4.082   1.00 87.53  ? 115 THR B CG2 1 
ATOM   4490  N N   . LYS B 1 116 ? 9.334   -31.988 1.215   1.00 52.99  ? 116 LYS B N   1 
ATOM   4491  C CA  . LYS B 1 116 ? 9.873   -30.668 0.941   1.00 58.72  ? 116 LYS B CA  1 
ATOM   4492  C C   . LYS B 1 116 ? 8.922   -29.812 0.078   1.00 61.95  ? 116 LYS B C   1 
ATOM   4493  O O   . LYS B 1 116 ? 8.632   -28.652 0.389   1.00 56.64  ? 116 LYS B O   1 
ATOM   4494  C CB  . LYS B 1 116 ? 11.224  -30.808 0.238   1.00 59.34  ? 116 LYS B CB  1 
ATOM   4495  C CG  . LYS B 1 116 ? 11.856  -29.494 -0.199  1.00 72.85  ? 116 LYS B CG  1 
ATOM   4496  C CD  . LYS B 1 116 ? 13.327  -29.613 -0.545  1.00 83.50  ? 116 LYS B CD  1 
ATOM   4497  C CE  . LYS B 1 116 ? 14.028  -28.270 -0.515  1.00 96.47  ? 116 LYS B CE  1 
ATOM   4498  N NZ  . LYS B 1 116 ? 15.498  -28.433 -0.617  1.00 102.29 ? 116 LYS B NZ  1 
ATOM   4499  N N   . ARG B 1 117 ? 8.478   -30.343 -1.066  1.00 54.77  ? 117 ARG B N   1 
ATOM   4500  C CA  . ARG B 1 117 ? 7.845   -29.510 -2.073  1.00 49.10  ? 117 ARG B CA  1 
ATOM   4501  C C   . ARG B 1 117 ? 6.449   -29.100 -1.596  1.00 40.82  ? 117 ARG B C   1 
ATOM   4502  O O   . ARG B 1 117 ? 5.925   -28.055 -1.980  1.00 39.61  ? 117 ARG B O   1 
ATOM   4503  C CB  . ARG B 1 117 ? 7.923   -30.234 -3.426  1.00 53.66  ? 117 ARG B CB  1 
ATOM   4504  C CG  . ARG B 1 117 ? 9.313   -30.169 -4.060  1.00 52.73  ? 117 ARG B CG  1 
ATOM   4505  C CD  . ARG B 1 117 ? 9.558   -31.131 -5.213  1.00 52.42  ? 117 ARG B CD  1 
ATOM   4506  N NE  . ARG B 1 117 ? 10.968  -31.174 -5.608  1.00 47.80  ? 117 ARG B NE  1 
ATOM   4507  C CZ  . ARG B 1 117 ? 11.487  -30.561 -6.681  1.00 56.64  ? 117 ARG B CZ  1 
ATOM   4508  N NH1 . ARG B 1 117 ? 10.749  -29.702 -7.373  1.00 54.01  ? 117 ARG B NH1 1 
ATOM   4509  N NH2 . ARG B 1 117 ? 12.750  -30.773 -7.048  1.00 51.39  ? 117 ARG B NH2 1 
ATOM   4510  N N   . MET B 1 118 ? 5.899   -29.890 -0.686  1.00 37.70  ? 118 MET B N   1 
ATOM   4511  C CA  . MET B 1 118 ? 4.570   -29.697 -0.123  1.00 42.08  ? 118 MET B CA  1 
ATOM   4512  C C   . MET B 1 118 ? 4.504   -28.417 0.716   1.00 47.10  ? 118 MET B C   1 
ATOM   4513  O O   . MET B 1 118 ? 3.425   -27.945 1.058   1.00 43.86  ? 118 MET B O   1 
ATOM   4514  C CB  . MET B 1 118 ? 4.301   -30.909 0.767   1.00 42.12  ? 118 MET B CB  1 
ATOM   4515  C CG  . MET B 1 118 ? 2.892   -31.131 1.157   1.00 46.53  ? 118 MET B CG  1 
ATOM   4516  S SD  . MET B 1 118 ? 2.570   -32.804 1.832   1.00 48.71  ? 118 MET B SD  1 
ATOM   4517  C CE  . MET B 1 118 ? 2.841   -33.839 0.403   1.00 50.59  ? 118 MET B CE  1 
ATOM   4518  N N   . GLN B 1 119 ? 5.671   -27.880 1.070   1.00 40.77  ? 119 GLN B N   1 
ATOM   4519  C CA  . GLN B 1 119 ? 5.806   -26.635 1.805   1.00 45.32  ? 119 GLN B CA  1 
ATOM   4520  C C   . GLN B 1 119 ? 5.860   -25.465 0.833   1.00 42.21  ? 119 GLN B C   1 
ATOM   4521  O O   . GLN B 1 119 ? 6.098   -24.353 1.253   1.00 38.50  ? 119 GLN B O   1 
ATOM   4522  C CB  . GLN B 1 119 ? 7.142   -26.575 2.567   1.00 52.19  ? 119 GLN B CB  1 
ATOM   4523  C CG  . GLN B 1 119 ? 7.387   -27.713 3.545   1.00 61.88  ? 119 GLN B CG  1 
ATOM   4524  C CD  . GLN B 1 119 ? 6.490   -27.603 4.752   1.00 68.31  ? 119 GLN B CD  1 
ATOM   4525  O OE1 . GLN B 1 119 ? 5.859   -26.572 4.974   1.00 71.49  ? 119 GLN B OE1 1 
ATOM   4526  N NE2 . GLN B 1 119 ? 6.454   -28.652 5.560   1.00 68.81  ? 119 GLN B NE2 1 
ATOM   4527  N N   . ASN B 1 120 ? 5.766   -25.727 -0.471  1.00 44.20  ? 120 ASN B N   1 
ATOM   4528  C CA  . ASN B 1 120 ? 6.064   -24.710 -1.461  1.00 43.22  ? 120 ASN B CA  1 
ATOM   4529  C C   . ASN B 1 120 ? 4.836   -24.445 -2.327  1.00 38.08  ? 120 ASN B C   1 
ATOM   4530  O O   . ASN B 1 120 ? 4.975   -24.098 -3.491  1.00 46.02  ? 120 ASN B O   1 
ATOM   4531  C CB  . ASN B 1 120 ? 7.286   -25.075 -2.325  1.00 58.07  ? 120 ASN B CB  1 
ATOM   4532  C CG  . ASN B 1 120 ? 8.619   -25.198 -1.594  1.00 62.15  ? 120 ASN B CG  1 
ATOM   4533  O OD1 . ASN B 1 120 ? 8.809   -24.694 -0.490  1.00 61.30  ? 120 ASN B OD1 1 
ATOM   4534  N ND2 . ASN B 1 120 ? 9.580   -25.853 -2.230  1.00 64.50  ? 120 ASN B ND2 1 
ATOM   4535  N N   . VAL B 1 121 ? 3.623   -24.590 -1.780  1.00 37.53  ? 121 VAL B N   1 
ATOM   4536  C CA  . VAL B 1 121 ? 2.442   -24.149 -2.514  1.00 33.58  ? 121 VAL B CA  1 
ATOM   4537  C C   . VAL B 1 121 ? 2.361   -22.633 -2.411  1.00 35.45  ? 121 VAL B C   1 
ATOM   4538  O O   . VAL B 1 121 ? 2.437   -22.061 -1.333  1.00 40.23  ? 121 VAL B O   1 
ATOM   4539  C CB  . VAL B 1 121 ? 1.182   -24.837 -1.996  1.00 36.34  ? 121 VAL B CB  1 
ATOM   4540  C CG1 . VAL B 1 121 ? -0.068  -24.437 -2.767  1.00 40.56  ? 121 VAL B CG1 1 
ATOM   4541  C CG2 . VAL B 1 121 ? 1.368   -26.346 -2.049  1.00 43.51  ? 121 VAL B CG2 1 
ATOM   4542  N N   . PRO B 1 122 ? 2.318   -21.895 -3.530  1.00 36.44  ? 122 PRO B N   1 
ATOM   4543  C CA  . PRO B 1 122 ? 2.218   -20.446 -3.445  1.00 34.67  ? 122 PRO B CA  1 
ATOM   4544  C C   . PRO B 1 122 ? 1.035   -19.973 -2.615  1.00 36.64  ? 122 PRO B C   1 
ATOM   4545  O O   . PRO B 1 122 ? -0.080  -20.495 -2.769  1.00 34.96  ? 122 PRO B O   1 
ATOM   4546  C CB  . PRO B 1 122 ? 2.012   -19.999 -4.898  1.00 33.61  ? 122 PRO B CB  1 
ATOM   4547  C CG  . PRO B 1 122 ? 2.678   -21.111 -5.713  1.00 32.24  ? 122 PRO B CG  1 
ATOM   4548  C CD  . PRO B 1 122 ? 2.536   -22.379 -4.898  1.00 32.01  ? 122 PRO B CD  1 
ATOM   4549  N N   . GLN B 1 123 ? 1.261   -18.891 -1.843  1.00 33.52  ? 123 GLN B N   1 
ATOM   4550  C CA  . GLN B 1 123 ? 0.176   -18.234 -1.121  1.00 34.16  ? 123 GLN B CA  1 
ATOM   4551  C C   . GLN B 1 123 ? -0.957  -17.861 -2.072  1.00 31.55  ? 123 GLN B C   1 
ATOM   4552  O O   . GLN B 1 123 ? -2.113  -17.993 -1.713  1.00 33.52  ? 123 GLN B O   1 
ATOM   4553  C CB  . GLN B 1 123 ? 0.724   -17.016 -0.387  1.00 39.53  ? 123 GLN B CB  1 
ATOM   4554  C CG  . GLN B 1 123 ? -0.308  -16.275 0.431   1.00 45.00  ? 123 GLN B CG  1 
ATOM   4555  C CD  . GLN B 1 123 ? -0.792  -17.109 1.588   1.00 53.62  ? 123 GLN B CD  1 
ATOM   4556  O OE1 . GLN B 1 123 ? 0.010   -17.544 2.407   1.00 66.84  ? 123 GLN B OE1 1 
ATOM   4557  N NE2 . GLN B 1 123 ? -2.101  -17.338 1.676   1.00 57.90  ? 123 GLN B NE2 1 
ATOM   4558  N N   . TYR B 1 124 ? -0.644  -17.411 -3.297  1.00 34.04  ? 124 TYR B N   1 
ATOM   4559  C CA  . TYR B 1 124 ? -1.663  -16.950 -4.228  1.00 32.00  ? 124 TYR B CA  1 
ATOM   4560  C C   . TYR B 1 124 ? -2.600  -18.073 -4.648  1.00 36.78  ? 124 TYR B C   1 
ATOM   4561  O O   . TYR B 1 124 ? -3.750  -17.794 -5.000  1.00 41.24  ? 124 TYR B O   1 
ATOM   4562  C CB  . TYR B 1 124 ? -1.055  -16.209 -5.430  1.00 36.31  ? 124 TYR B CB  1 
ATOM   4563  C CG  . TYR B 1 124 ? -0.257  -17.071 -6.363  1.00 41.06  ? 124 TYR B CG  1 
ATOM   4564  C CD1 . TYR B 1 124 ? -0.894  -17.924 -7.248  1.00 40.37  ? 124 TYR B CD1 1 
ATOM   4565  C CD2 . TYR B 1 124 ? 1.137   -17.057 -6.362  1.00 41.99  ? 124 TYR B CD2 1 
ATOM   4566  C CE1 . TYR B 1 124 ? -0.180  -18.737 -8.118  1.00 37.19  ? 124 TYR B CE1 1 
ATOM   4567  C CE2 . TYR B 1 124 ? 1.866   -17.888 -7.202  1.00 37.59  ? 124 TYR B CE2 1 
ATOM   4568  C CZ  . TYR B 1 124 ? 1.204   -18.742 -8.078  1.00 38.67  ? 124 TYR B CZ  1 
ATOM   4569  O OH  . TYR B 1 124 ? 1.873   -19.643 -8.902  1.00 40.33  ? 124 TYR B OH  1 
ATOM   4570  N N   . VAL B 1 125 ? -2.162  -19.340 -4.577  1.00 36.14  ? 125 VAL B N   1 
ATOM   4571  C CA  . VAL B 1 125 ? -3.068  -20.441 -4.848  1.00 31.09  ? 125 VAL B CA  1 
ATOM   4572  C C   . VAL B 1 125 ? -4.196  -20.416 -3.827  1.00 33.84  ? 125 VAL B C   1 
ATOM   4573  O O   . VAL B 1 125 ? -5.369  -20.578 -4.158  1.00 38.50  ? 125 VAL B O   1 
ATOM   4574  C CB  . VAL B 1 125 ? -2.337  -21.800 -4.887  1.00 31.81  ? 125 VAL B CB  1 
ATOM   4575  C CG1 . VAL B 1 125 ? -3.267  -22.988 -4.954  1.00 34.12  ? 125 VAL B CG1 1 
ATOM   4576  C CG2 . VAL B 1 125 ? -1.373  -21.868 -6.032  1.00 35.42  ? 125 VAL B CG2 1 
ATOM   4577  N N   . PHE B 1 126 ? -3.859  -20.218 -2.560  1.00 36.22  ? 126 PHE B N   1 
ATOM   4578  C CA  . PHE B 1 126 ? -4.906  -20.132 -1.553  1.00 38.23  ? 126 PHE B CA  1 
ATOM   4579  C C   . PHE B 1 126 ? -5.804  -18.927 -1.794  1.00 35.39  ? 126 PHE B C   1 
ATOM   4580  O O   . PHE B 1 126 ? -6.985  -19.009 -1.528  1.00 37.27  ? 126 PHE B O   1 
ATOM   4581  C CB  . PHE B 1 126 ? -4.292  -20.108 -0.153  1.00 41.13  ? 126 PHE B CB  1 
ATOM   4582  C CG  . PHE B 1 126 ? -3.455  -21.335 0.074   1.00 39.90  ? 126 PHE B CG  1 
ATOM   4583  C CD1 . PHE B 1 126 ? -4.059  -22.557 0.261   1.00 41.47  ? 126 PHE B CD1 1 
ATOM   4584  C CD2 . PHE B 1 126 ? -2.075  -21.276 -0.012  1.00 45.89  ? 126 PHE B CD2 1 
ATOM   4585  C CE1 . PHE B 1 126 ? -3.300  -23.697 0.437   1.00 49.48  ? 126 PHE B CE1 1 
ATOM   4586  C CE2 . PHE B 1 126 ? -1.310  -22.412 0.174   1.00 49.54  ? 126 PHE B CE2 1 
ATOM   4587  C CZ  . PHE B 1 126 ? -1.924  -23.618 0.411   1.00 55.07  ? 126 PHE B CZ  1 
ATOM   4588  N N   . ASP B 1 127 ? -5.230  -17.788 -2.205  1.00 34.46  ? 127 ASP B N   1 
ATOM   4589  C CA  . ASP B 1 127 ? -6.015  -16.610 -2.489  1.00 33.88  ? 127 ASP B CA  1 
ATOM   4590  C C   . ASP B 1 127 ? -7.014  -16.958 -3.587  1.00 32.94  ? 127 ASP B C   1 
ATOM   4591  O O   . ASP B 1 127 ? -8.172  -16.603 -3.491  1.00 38.22  ? 127 ASP B O   1 
ATOM   4592  C CB  . ASP B 1 127 ? -5.138  -15.428 -2.913  1.00 40.14  ? 127 ASP B CB  1 
ATOM   4593  C CG  . ASP B 1 127 ? -4.122  -14.948 -1.882  1.00 37.38  ? 127 ASP B CG  1 
ATOM   4594  O OD1 . ASP B 1 127 ? -4.251  -15.309 -0.699  1.00 41.58  ? 127 ASP B OD1 1 
ATOM   4595  O OD2 . ASP B 1 127 ? -3.204  -14.184 -2.273  1.00 42.58  ? 127 ASP B OD2 1 
ATOM   4596  N N   . VAL B 1 128 ? -6.577  -17.684 -4.609  1.00 29.92  ? 128 VAL B N   1 
ATOM   4597  C CA  . VAL B 1 128 ? -7.474  -18.064 -5.687  1.00 32.92  ? 128 VAL B CA  1 
ATOM   4598  C C   . VAL B 1 128 ? -8.613  -18.921 -5.141  1.00 35.53  ? 128 VAL B C   1 
ATOM   4599  O O   . VAL B 1 128 ? -9.783  -18.659 -5.443  1.00 32.64  ? 128 VAL B O   1 
ATOM   4600  C CB  . VAL B 1 128 ? -6.731  -18.795 -6.816  1.00 32.86  ? 128 VAL B CB  1 
ATOM   4601  C CG1 . VAL B 1 128 ? -7.665  -19.623 -7.673  1.00 35.52  ? 128 VAL B CG1 1 
ATOM   4602  C CG2 . VAL B 1 128 ? -5.944  -17.827 -7.678  1.00 28.67  ? 128 VAL B CG2 1 
ATOM   4603  N N   . LEU B 1 129 ? -8.263  -19.930 -4.331  1.00 38.44  ? 129 LEU B N   1 
ATOM   4604  C CA  . LEU B 1 129 ? -9.237  -20.824 -3.719  1.00 37.55  ? 129 LEU B CA  1 
ATOM   4605  C C   . LEU B 1 129 ? -10.250 -20.093 -2.845  1.00 37.41  ? 129 LEU B C   1 
ATOM   4606  O O   . LEU B 1 129 ? -11.430 -20.388 -2.942  1.00 45.54  ? 129 LEU B O   1 
ATOM   4607  C CB  . LEU B 1 129 ? -8.496  -21.884 -2.891  1.00 44.12  ? 129 LEU B CB  1 
ATOM   4608  C CG  . LEU B 1 129 ? -7.771  -22.941 -3.718  1.00 38.75  ? 129 LEU B CG  1 
ATOM   4609  C CD1 . LEU B 1 129 ? -6.847  -23.765 -2.854  1.00 40.40  ? 129 LEU B CD1 1 
ATOM   4610  C CD2 . LEU B 1 129 ? -8.771  -23.831 -4.429  1.00 39.46  ? 129 LEU B CD2 1 
ATOM   4611  N N   . ARG B 1 130 ? -9.815  -19.158 -1.987  1.00 38.60  ? 130 ARG B N   1 
ATOM   4612  C CA  . ARG B 1 130 ? -10.740 -18.406 -1.134  1.00 36.09  ? 130 ARG B CA  1 
ATOM   4613  C C   . ARG B 1 130 ? -11.603 -17.438 -1.939  1.00 31.58  ? 130 ARG B C   1 
ATOM   4614  O O   . ARG B 1 130 ? -12.652 -17.037 -1.499  1.00 34.66  ? 130 ARG B O   1 
ATOM   4615  C CB  . ARG B 1 130 ? -10.041 -17.593 -0.035  1.00 37.81  ? 130 ARG B CB  1 
ATOM   4616  C CG  . ARG B 1 130 ? -9.473  -18.432 1.096   1.00 45.87  ? 130 ARG B CG  1 
ATOM   4617  C CD  . ARG B 1 130 ? -9.045  -17.599 2.299   1.00 52.43  ? 130 ARG B CD  1 
ATOM   4618  N NE  . ARG B 1 130 ? -10.123 -17.330 3.230   1.00 43.12  ? 130 ARG B NE  1 
ATOM   4619  C CZ  . ARG B 1 130 ? -10.722 -18.242 3.980   1.00 43.83  ? 130 ARG B CZ  1 
ATOM   4620  N NH1 . ARG B 1 130 ? -11.643 -17.860 4.842   1.00 42.44  ? 130 ARG B NH1 1 
ATOM   4621  N NH2 . ARG B 1 130 ? -10.393 -19.524 3.893   1.00 41.95  ? 130 ARG B NH2 1 
ATOM   4622  N N   . ALA B 1 131 ? -11.152 -16.988 -3.097  1.00 34.33  ? 131 ALA B N   1 
ATOM   4623  C CA  . ALA B 1 131 ? -11.959 -16.084 -3.899  1.00 32.02  ? 131 ALA B CA  1 
ATOM   4624  C C   . ALA B 1 131 ? -13.168 -16.798 -4.529  1.00 35.03  ? 131 ALA B C   1 
ATOM   4625  O O   . ALA B 1 131 ? -14.107 -16.156 -4.984  1.00 33.38  ? 131 ALA B O   1 
ATOM   4626  C CB  . ALA B 1 131 ? -11.056 -15.507 -4.955  1.00 37.78  ? 131 ALA B CB  1 
ATOM   4627  N N   . MET B 1 132 ? -13.117 -18.134 -4.663  1.00 37.80  ? 132 MET B N   1 
ATOM   4628  C CA  . MET B 1 132 ? -14.242 -18.856 -5.214  1.00 34.42  ? 132 MET B CA  1 
ATOM   4629  C C   . MET B 1 132 ? -15.272 -19.031 -4.106  1.00 38.41  ? 132 MET B C   1 
ATOM   4630  O O   . MET B 1 132 ? -14.940 -19.338 -2.963  1.00 38.65  ? 132 MET B O   1 
ATOM   4631  C CB  . MET B 1 132 ? -13.841 -20.228 -5.719  1.00 35.95  ? 132 MET B CB  1 
ATOM   4632  C CG  . MET B 1 132 ? -12.927 -20.147 -6.912  1.00 41.96  ? 132 MET B CG  1 
ATOM   4633  S SD  . MET B 1 132 ? -12.150 -21.769 -7.169  1.00 43.33  ? 132 MET B SD  1 
ATOM   4634  C CE  . MET B 1 132 ? -13.089 -22.330 -8.574  1.00 40.58  ? 132 MET B CE  1 
ATOM   4635  N N   . PRO B 1 133 ? -16.568 -18.883 -4.420  1.00 34.43  ? 133 PRO B N   1 
ATOM   4636  C CA  . PRO B 1 133 ? -17.593 -19.071 -3.410  1.00 35.34  ? 133 PRO B CA  1 
ATOM   4637  C C   . PRO B 1 133 ? -17.543 -20.496 -2.847  1.00 37.47  ? 133 PRO B C   1 
ATOM   4638  O O   . PRO B 1 133 ? -17.359 -21.479 -3.574  1.00 36.91  ? 133 PRO B O   1 
ATOM   4639  C CB  . PRO B 1 133 ? -18.900 -18.800 -4.161  1.00 37.22  ? 133 PRO B CB  1 
ATOM   4640  C CG  . PRO B 1 133 ? -18.502 -18.080 -5.421  1.00 36.83  ? 133 PRO B CG  1 
ATOM   4641  C CD  . PRO B 1 133 ? -17.088 -18.506 -5.739  1.00 33.95  ? 133 PRO B CD  1 
ATOM   4642  N N   . VAL B 1 134 ? -17.743 -20.606 -1.536  1.00 33.83  ? 134 VAL B N   1 
ATOM   4643  C CA  . VAL B 1 134 ? -17.484 -21.837 -0.815  1.00 30.36  ? 134 VAL B CA  1 
ATOM   4644  C C   . VAL B 1 134 ? -18.414 -22.973 -1.275  1.00 37.87  ? 134 VAL B C   1 
ATOM   4645  O O   . VAL B 1 134 ? -18.059 -24.154 -1.176  1.00 38.10  ? 134 VAL B O   1 
ATOM   4646  C CB  . VAL B 1 134 ? -17.548 -21.534 0.677   1.00 31.55  ? 134 VAL B CB  1 
ATOM   4647  C CG1 . VAL B 1 134 ? -18.982 -21.314 1.120   1.00 34.29  ? 134 VAL B CG1 1 
ATOM   4648  C CG2 . VAL B 1 134 ? -16.840 -22.586 1.531   1.00 29.66  ? 134 VAL B CG2 1 
ATOM   4649  N N   . ASP B 1 135 ? -19.561 -22.633 -1.883  1.00 38.54  ? 135 ASP B N   1 
ATOM   4650  C CA  . ASP B 1 135 ? -20.493 -23.629 -2.412  1.00 40.15  ? 135 ASP B CA  1 
ATOM   4651  C C   . ASP B 1 135 ? -20.097 -24.057 -3.839  1.00 39.86  ? 135 ASP B C   1 
ATOM   4652  O O   . ASP B 1 135 ? -20.766 -24.883 -4.436  1.00 38.61  ? 135 ASP B O   1 
ATOM   4653  C CB  . ASP B 1 135 ? -21.958 -23.150 -2.320  1.00 38.41  ? 135 ASP B CB  1 
ATOM   4654  C CG  . ASP B 1 135 ? -22.293 -21.916 -3.171  1.00 42.72  ? 135 ASP B CG  1 
ATOM   4655  O OD1 . ASP B 1 135 ? -21.404 -21.438 -3.880  1.00 45.84  ? 135 ASP B OD1 1 
ATOM   4656  O OD2 . ASP B 1 135 ? -23.449 -21.436 -3.145  1.00 39.39  ? 135 ASP B OD2 1 
ATOM   4657  N N   . THR B 1 136 ? -18.989 -23.565 -4.400  1.00 43.56  ? 136 THR B N   1 
ATOM   4658  C CA  . THR B 1 136 ? -18.543 -24.095 -5.683  1.00 39.50  ? 136 THR B CA  1 
ATOM   4659  C C   . THR B 1 136 ? -18.232 -25.582 -5.536  1.00 40.77  ? 136 THR B C   1 
ATOM   4660  O O   . THR B 1 136 ? -17.712 -26.003 -4.503  1.00 41.78  ? 136 THR B O   1 
ATOM   4661  C CB  . THR B 1 136 ? -17.300 -23.370 -6.200  1.00 39.22  ? 136 THR B CB  1 
ATOM   4662  O OG1 . THR B 1 136 ? -17.527 -21.964 -6.173  1.00 37.83  ? 136 THR B OG1 1 
ATOM   4663  C CG2 . THR B 1 136 ? -16.922 -23.807 -7.601  1.00 38.28  ? 136 THR B CG2 1 
ATOM   4664  N N   . HIS B 1 137 ? -18.518 -26.377 -6.574  1.00 36.45  ? 137 HIS B N   1 
ATOM   4665  C CA  . HIS B 1 137 ? -18.254 -27.808 -6.508  1.00 39.43  ? 137 HIS B CA  1 
ATOM   4666  C C   . HIS B 1 137 ? -16.761 -28.069 -6.274  1.00 35.90  ? 137 HIS B C   1 
ATOM   4667  O O   . HIS B 1 137 ? -15.927 -27.409 -6.880  1.00 36.28  ? 137 HIS B O   1 
ATOM   4668  C CB  . HIS B 1 137 ? -18.732 -28.462 -7.806  1.00 41.61  ? 137 HIS B CB  1 
ATOM   4669  C CG  . HIS B 1 137 ? -18.655 -29.956 -7.801  1.00 43.01  ? 137 HIS B CG  1 
ATOM   4670  N ND1 . HIS B 1 137 ? -17.465 -30.651 -7.774  1.00 45.11  ? 137 HIS B ND1 1 
ATOM   4671  C CD2 . HIS B 1 137 ? -19.633 -30.881 -7.833  1.00 43.21  ? 137 HIS B CD2 1 
ATOM   4672  C CE1 . HIS B 1 137 ? -17.719 -31.948 -7.761  1.00 40.18  ? 137 HIS B CE1 1 
ATOM   4673  N NE2 . HIS B 1 137 ? -19.037 -32.109 -7.796  1.00 41.89  ? 137 HIS B NE2 1 
ATOM   4674  N N   . PRO B 1 138 ? -16.342 -29.045 -5.438  1.00 31.38  ? 138 PRO B N   1 
ATOM   4675  C CA  . PRO B 1 138 ? -14.939 -29.141 -5.051  1.00 31.09  ? 138 PRO B CA  1 
ATOM   4676  C C   . PRO B 1 138 ? -14.006 -29.471 -6.207  1.00 32.50  ? 138 PRO B C   1 
ATOM   4677  O O   . PRO B 1 138 ? -12.816 -29.169 -6.142  1.00 33.56  ? 138 PRO B O   1 
ATOM   4678  C CB  . PRO B 1 138 ? -14.879 -30.263 -4.004  1.00 35.75  ? 138 PRO B CB  1 
ATOM   4679  C CG  . PRO B 1 138 ? -16.190 -30.986 -4.131  1.00 39.61  ? 138 PRO B CG  1 
ATOM   4680  C CD  . PRO B 1 138 ? -17.180 -29.980 -4.692  1.00 37.32  ? 138 PRO B CD  1 
ATOM   4681  N N   . MET B 1 139 ? -14.536 -30.124 -7.246  1.00 33.55  ? 139 MET B N   1 
ATOM   4682  C CA  . MET B 1 139 ? -13.711 -30.505 -8.381  1.00 32.43  ? 139 MET B CA  1 
ATOM   4683  C C   . MET B 1 139 ? -13.440 -29.280 -9.232  1.00 34.38  ? 139 MET B C   1 
ATOM   4684  O O   . MET B 1 139 ? -12.386 -29.195 -9.861  1.00 36.86  ? 139 MET B O   1 
ATOM   4685  C CB  . MET B 1 139 ? -14.375 -31.588 -9.227  1.00 35.93  ? 139 MET B CB  1 
ATOM   4686  C CG  . MET B 1 139 ? -14.142 -32.991 -8.654  1.00 33.99  ? 139 MET B CG  1 
ATOM   4687  S SD  . MET B 1 139 ? -12.418 -33.472 -8.828  1.00 38.94  ? 139 MET B SD  1 
ATOM   4688  C CE  . MET B 1 139 ? -12.372 -33.858 -10.576 1.00 46.83  ? 139 MET B CE  1 
ATOM   4689  N N   . THR B 1 140 ? -14.352 -28.298 -9.179  1.00 33.63  ? 140 THR B N   1 
ATOM   4690  C CA  . THR B 1 140 ? -14.089 -27.019 -9.835  1.00 37.46  ? 140 THR B CA  1 
ATOM   4691  C C   . THR B 1 140 ? -12.992 -26.282 -9.077  1.00 34.17  ? 140 THR B C   1 
ATOM   4692  O O   . THR B 1 140 ? -12.101 -25.693 -9.654  1.00 36.71  ? 140 THR B O   1 
ATOM   4693  C CB  . THR B 1 140 ? -15.355 -26.162 -9.958  1.00 36.24  ? 140 THR B CB  1 
ATOM   4694  O OG1 . THR B 1 140 ? -16.273 -26.906 -10.744 1.00 38.59  ? 140 THR B OG1 1 
ATOM   4695  C CG2 . THR B 1 140 ? -15.135 -24.823 -10.633 1.00 39.91  ? 140 THR B CG2 1 
ATOM   4696  N N   . MET B 1 141 ? -13.068 -26.341 -7.754  1.00 37.14  ? 141 MET B N   1 
ATOM   4697  C CA  . MET B 1 141 ? -12.100 -25.692 -6.902  1.00 34.21  ? 141 MET B CA  1 
ATOM   4698  C C   . MET B 1 141 ? -10.739 -26.366 -7.112  1.00 37.34  ? 141 MET B C   1 
ATOM   4699  O O   . MET B 1 141 ? -9.713  -25.706 -7.121  1.00 37.50  ? 141 MET B O   1 
ATOM   4700  C CB  . MET B 1 141 ? -12.521 -25.853 -5.443  1.00 32.33  ? 141 MET B CB  1 
ATOM   4701  C CG  . MET B 1 141 ? -13.609 -24.919 -4.973  1.00 34.32  ? 141 MET B CG  1 
ATOM   4702  S SD  . MET B 1 141 ? -13.721 -25.106 -3.175  1.00 39.36  ? 141 MET B SD  1 
ATOM   4703  C CE  . MET B 1 141 ? -15.143 -24.112 -2.731  1.00 40.27  ? 141 MET B CE  1 
ATOM   4704  N N   . PHE B 1 142 ? -10.740 -27.694 -7.224  1.00 34.30  ? 142 PHE B N   1 
ATOM   4705  C CA  . PHE B 1 142 ? -9.510  -28.451 -7.342  1.00 34.07  ? 142 PHE B CA  1 
ATOM   4706  C C   . PHE B 1 142 ? -8.818  -28.109 -8.661  1.00 35.22  ? 142 PHE B C   1 
ATOM   4707  O O   . PHE B 1 142 ? -7.619  -27.788 -8.661  1.00 36.17  ? 142 PHE B O   1 
ATOM   4708  C CB  . PHE B 1 142 ? -9.816  -29.941 -7.148  1.00 35.58  ? 142 PHE B CB  1 
ATOM   4709  C CG  . PHE B 1 142 ? -8.629  -30.874 -7.144  1.00 32.91  ? 142 PHE B CG  1 
ATOM   4710  C CD1 . PHE B 1 142 ? -7.607  -30.727 -6.218  1.00 35.98  ? 142 PHE B CD1 1 
ATOM   4711  C CD2 . PHE B 1 142 ? -8.569  -31.942 -8.021  1.00 35.14  ? 142 PHE B CD2 1 
ATOM   4712  C CE1 . PHE B 1 142 ? -6.530  -31.596 -6.198  1.00 38.60  ? 142 PHE B CE1 1 
ATOM   4713  C CE2 . PHE B 1 142 ? -7.528  -32.855 -7.961  1.00 38.68  ? 142 PHE B CE2 1 
ATOM   4714  C CZ  . PHE B 1 142 ? -6.492  -32.665 -7.070  1.00 40.04  ? 142 PHE B CZ  1 
ATOM   4715  N N   . ALA B 1 143 ? -9.561  -28.169 -9.777  1.00 33.08  ? 143 ALA B N   1 
ATOM   4716  C CA  . ALA B 1 143 ? -9.004  -27.824 -11.081 1.00 33.03  ? 143 ALA B CA  1 
ATOM   4717  C C   . ALA B 1 143 ? -8.464  -26.389 -11.112 1.00 31.90  ? 143 ALA B C   1 
ATOM   4718  O O   . ALA B 1 143 ? -7.387  -26.105 -11.644 1.00 37.89  ? 143 ALA B O   1 
ATOM   4719  C CB  . ALA B 1 143 ? -10.058 -28.021 -12.142 1.00 29.96  ? 143 ALA B CB  1 
ATOM   4720  N N   . ALA B 1 144 ? -9.207  -25.459 -10.542 1.00 30.49  ? 144 ALA B N   1 
ATOM   4721  C CA  . ALA B 1 144 ? -8.791  -24.060 -10.513 1.00 30.53  ? 144 ALA B CA  1 
ATOM   4722  C C   . ALA B 1 144 ? -7.490  -23.843 -9.736  1.00 34.63  ? 144 ALA B C   1 
ATOM   4723  O O   . ALA B 1 144 ? -6.643  -23.037 -10.151 1.00 35.64  ? 144 ALA B O   1 
ATOM   4724  C CB  . ALA B 1 144 ? -9.913  -23.254 -9.916  1.00 32.90  ? 144 ALA B CB  1 
ATOM   4725  N N   . GLY B 1 145 ? -7.322  -24.517 -8.584  1.00 33.37  ? 145 GLY B N   1 
ATOM   4726  C CA  . GLY B 1 145 ? -6.109  -24.308 -7.799  1.00 31.86  ? 145 GLY B CA  1 
ATOM   4727  C C   . GLY B 1 145 ? -4.871  -24.769 -8.562  1.00 36.48  ? 145 GLY B C   1 
ATOM   4728  O O   . GLY B 1 145 ? -3.855  -24.060 -8.644  1.00 30.88  ? 145 GLY B O   1 
ATOM   4729  N N   . ILE B 1 146 ? -5.007  -25.966 -9.163  1.00 38.48  ? 146 ILE B N   1 
ATOM   4730  C CA  . ILE B 1 146 ? -3.949  -26.572 -9.934  1.00 34.01  ? 146 ILE B CA  1 
ATOM   4731  C C   . ILE B 1 146 ? -3.539  -25.605 -11.045 1.00 35.65  ? 146 ILE B C   1 
ATOM   4732  O O   . ILE B 1 146 ? -2.351  -25.333 -11.242 1.00 31.06  ? 146 ILE B O   1 
ATOM   4733  C CB  . ILE B 1 146 ? -4.404  -27.933 -10.500 1.00 38.23  ? 146 ILE B CB  1 
ATOM   4734  C CG1 . ILE B 1 146 ? -4.784  -28.918 -9.381  1.00 40.92  ? 146 ILE B CG1 1 
ATOM   4735  C CG2 . ILE B 1 146 ? -3.298  -28.505 -11.379 1.00 36.15  ? 146 ILE B CG2 1 
ATOM   4736  C CD1 . ILE B 1 146 ? -5.447  -30.181 -9.870  1.00 38.36  ? 146 ILE B CD1 1 
ATOM   4737  N N   . LEU B 1 147 ? -4.531  -25.138 -11.809 1.00 34.36  ? 147 LEU B N   1 
ATOM   4738  C CA  . LEU B 1 147 ? -4.275  -24.305 -12.969 1.00 34.35  ? 147 LEU B CA  1 
ATOM   4739  C C   . LEU B 1 147 ? -3.602  -23.004 -12.553 1.00 34.24  ? 147 LEU B C   1 
ATOM   4740  O O   . LEU B 1 147 ? -2.755  -22.494 -13.292 1.00 35.28  ? 147 LEU B O   1 
ATOM   4741  C CB  . LEU B 1 147 ? -5.611  -23.990 -13.635 1.00 38.10  ? 147 LEU B CB  1 
ATOM   4742  C CG  . LEU B 1 147 ? -5.557  -23.022 -14.804 1.00 40.58  ? 147 LEU B CG  1 
ATOM   4743  C CD1 . LEU B 1 147 ? -4.625  -23.546 -15.886 1.00 40.19  ? 147 LEU B CD1 1 
ATOM   4744  C CD2 . LEU B 1 147 ? -6.961  -22.805 -15.339 1.00 41.08  ? 147 LEU B CD2 1 
ATOM   4745  N N   . ALA B 1 148 ? -3.997  -22.446 -11.401 1.00 32.83  ? 148 ALA B N   1 
ATOM   4746  C CA  . ALA B 1 148 ? -3.414  -21.184 -10.955 1.00 34.59  ? 148 ALA B CA  1 
ATOM   4747  C C   . ALA B 1 148 ? -1.920  -21.383 -10.689 1.00 37.35  ? 148 ALA B C   1 
ATOM   4748  O O   . ALA B 1 148 ? -1.121  -20.454 -10.776 1.00 33.55  ? 148 ALA B O   1 
ATOM   4749  C CB  . ALA B 1 148 ? -4.089  -20.658 -9.726  1.00 32.18  ? 148 ALA B CB  1 
ATOM   4750  N N   . MET B 1 149 ? -1.537  -22.630 -10.429 1.00 33.77  ? 149 MET B N   1 
ATOM   4751  C CA  . MET B 1 149 ? -0.166  -22.888 -10.083 1.00 32.17  ? 149 MET B CA  1 
ATOM   4752  C C   . MET B 1 149 ? 0.660   -22.990 -11.366 1.00 32.95  ? 149 MET B C   1 
ATOM   4753  O O   . MET B 1 149 ? 1.873   -23.021 -11.315 1.00 34.71  ? 149 MET B O   1 
ATOM   4754  C CB  . MET B 1 149 ? -0.106  -24.127 -9.215  1.00 32.95  ? 149 MET B CB  1 
ATOM   4755  C CG  . MET B 1 149 ? 1.187   -24.307 -8.542  1.00 35.11  ? 149 MET B CG  1 
ATOM   4756  S SD  . MET B 1 149 ? 1.021   -25.531 -7.216  1.00 38.44  ? 149 MET B SD  1 
ATOM   4757  C CE  . MET B 1 149 ? 2.784   -25.689 -6.910  1.00 36.74  ? 149 MET B CE  1 
ATOM   4758  N N   . GLN B 1 150 ? 0.019   -22.856 -12.531 1.00 33.51  ? 150 GLN B N   1 
ATOM   4759  C CA  . GLN B 1 150 ? 0.743   -22.898 -13.778 1.00 32.67  ? 150 GLN B CA  1 
ATOM   4760  C C   . GLN B 1 150 ? 1.846   -21.844 -13.833 1.00 37.34  ? 150 GLN B C   1 
ATOM   4761  O O   . GLN B 1 150 ? 2.809   -22.026 -14.562 1.00 37.03  ? 150 GLN B O   1 
ATOM   4762  C CB  . GLN B 1 150 ? -0.222  -22.758 -14.949 1.00 31.68  ? 150 GLN B CB  1 
ATOM   4763  C CG  . GLN B 1 150 ? 0.447   -22.977 -16.305 1.00 33.04  ? 150 GLN B CG  1 
ATOM   4764  C CD  . GLN B 1 150 ? 1.085   -21.719 -16.839 1.00 40.17  ? 150 GLN B CD  1 
ATOM   4765  O OE1 . GLN B 1 150 ? 0.672   -20.599 -16.512 1.00 40.83  ? 150 GLN B OE1 1 
ATOM   4766  N NE2 . GLN B 1 150 ? 2.092   -21.886 -17.688 1.00 32.22  ? 150 GLN B NE2 1 
ATOM   4767  N N   . ARG B 1 151 ? 1.707   -20.755 -13.058 1.00 40.65  ? 151 ARG B N   1 
ATOM   4768  C CA  . ARG B 1 151 ? 2.674   -19.667 -13.022 1.00 39.46  ? 151 ARG B CA  1 
ATOM   4769  C C   . ARG B 1 151 ? 4.066   -20.183 -12.647 1.00 34.07  ? 151 ARG B C   1 
ATOM   4770  O O   . ARG B 1 151 ? 5.056   -19.627 -13.089 1.00 34.85  ? 151 ARG B O   1 
ATOM   4771  C CB  . ARG B 1 151 ? 2.250   -18.557 -12.045 1.00 41.28  ? 151 ARG B CB  1 
ATOM   4772  C CG  . ARG B 1 151 ? 3.311   -17.463 -11.853 1.00 39.45  ? 151 ARG B CG  1 
ATOM   4773  C CD  . ARG B 1 151 ? 2.827   -16.446 -10.832 1.00 46.83  ? 151 ARG B CD  1 
ATOM   4774  N NE  . ARG B 1 151 ? 3.693   -15.288 -10.589 1.00 50.07  ? 151 ARG B NE  1 
ATOM   4775  C CZ  . ARG B 1 151 ? 4.743   -15.272 -9.775  1.00 49.66  ? 151 ARG B CZ  1 
ATOM   4776  N NH1 . ARG B 1 151 ? 5.004   -16.329 -9.029  1.00 40.11  ? 151 ARG B NH1 1 
ATOM   4777  N NH2 . ARG B 1 151 ? 5.526   -14.200 -9.715  1.00 55.54  ? 151 ARG B NH2 1 
ATOM   4778  N N   . GLU B 1 152 ? 4.128   -21.260 -11.874 1.00 35.75  ? 152 GLU B N   1 
ATOM   4779  C CA  . GLU B 1 152 ? 5.383   -21.882 -11.477 1.00 40.16  ? 152 GLU B CA  1 
ATOM   4780  C C   . GLU B 1 152 ? 5.924   -22.907 -12.487 1.00 41.17  ? 152 GLU B C   1 
ATOM   4781  O O   . GLU B 1 152 ? 6.866   -23.616 -12.166 1.00 43.17  ? 152 GLU B O   1 
ATOM   4782  C CB  . GLU B 1 152 ? 5.153   -22.589 -10.133 1.00 37.60  ? 152 GLU B CB  1 
ATOM   4783  C CG  . GLU B 1 152 ? 4.639   -21.655 -9.039  1.00 41.33  ? 152 GLU B CG  1 
ATOM   4784  C CD  . GLU B 1 152 ? 5.207   -20.233 -9.007  1.00 41.13  ? 152 GLU B CD  1 
ATOM   4785  O OE1 . GLU B 1 152 ? 4.418   -19.273 -8.975  1.00 35.42  ? 152 GLU B OE1 1 
ATOM   4786  O OE2 . GLU B 1 152 ? 6.440   -20.072 -9.062  1.00 48.17  ? 152 GLU B OE2 1 
ATOM   4787  N N   . SER B 1 153 ? 5.382   -23.001 -13.708 1.00 42.27  ? 153 SER B N   1 
ATOM   4788  C CA  . SER B 1 153 ? 5.771   -24.079 -14.613 1.00 42.21  ? 153 SER B CA  1 
ATOM   4789  C C   . SER B 1 153 ? 7.193   -23.872 -15.104 1.00 39.73  ? 153 SER B C   1 
ATOM   4790  O O   . SER B 1 153 ? 7.477   -22.856 -15.739 1.00 40.36  ? 153 SER B O   1 
ATOM   4791  C CB  . SER B 1 153 ? 4.864   -24.222 -15.819 1.00 42.51  ? 153 SER B CB  1 
ATOM   4792  O OG  . SER B 1 153 ? 5.391   -25.184 -16.716 1.00 41.06  ? 153 SER B OG  1 
ATOM   4793  N N   . VAL B 1 154 ? 8.024   -24.897 -14.865 1.00 45.33  ? 154 VAL B N   1 
ATOM   4794  C CA  . VAL B 1 154 ? 9.413   -24.934 -15.316 1.00 47.09  ? 154 VAL B CA  1 
ATOM   4795  C C   . VAL B 1 154 ? 9.425   -25.246 -16.811 1.00 45.60  ? 154 VAL B C   1 
ATOM   4796  O O   . VAL B 1 154 ? 10.115  -24.600 -17.599 1.00 45.33  ? 154 VAL B O   1 
ATOM   4797  C CB  . VAL B 1 154 ? 10.202  -25.961 -14.483 1.00 55.51  ? 154 VAL B CB  1 
ATOM   4798  C CG1 . VAL B 1 154 ? 11.552  -26.291 -15.104 1.00 59.55  ? 154 VAL B CG1 1 
ATOM   4799  C CG2 . VAL B 1 154 ? 10.356  -25.499 -13.035 1.00 45.37  ? 154 VAL B CG2 1 
ATOM   4800  N N   . PHE B 1 155 ? 8.556   -26.177 -17.218 1.00 49.69  ? 155 PHE B N   1 
ATOM   4801  C CA  . PHE B 1 155 ? 8.376   -26.453 -18.633 1.00 40.48  ? 155 PHE B CA  1 
ATOM   4802  C C   . PHE B 1 155 ? 8.034   -25.172 -19.409 1.00 45.05  ? 155 PHE B C   1 
ATOM   4803  O O   . PHE B 1 155 ? 8.715   -24.829 -20.381 1.00 45.20  ? 155 PHE B O   1 
ATOM   4804  C CB  . PHE B 1 155 ? 7.368   -27.577 -18.782 1.00 34.12  ? 155 PHE B CB  1 
ATOM   4805  C CG  . PHE B 1 155 ? 7.252   -28.083 -20.194 1.00 43.79  ? 155 PHE B CG  1 
ATOM   4806  C CD1 . PHE B 1 155 ? 6.601   -27.348 -21.173 1.00 41.97  ? 155 PHE B CD1 1 
ATOM   4807  C CD2 . PHE B 1 155 ? 7.865   -29.265 -20.557 1.00 44.77  ? 155 PHE B CD2 1 
ATOM   4808  C CE1 . PHE B 1 155 ? 6.512   -27.816 -22.472 1.00 56.06  ? 155 PHE B CE1 1 
ATOM   4809  C CE2 . PHE B 1 155 ? 7.789   -29.722 -21.863 1.00 51.24  ? 155 PHE B CE2 1 
ATOM   4810  C CZ  . PHE B 1 155 ? 7.106   -29.009 -22.819 1.00 49.23  ? 155 PHE B CZ  1 
ATOM   4811  N N   . ALA B 1 156 ? 6.979   -24.452 -19.012 1.00 42.23  ? 156 ALA B N   1 
ATOM   4812  C CA  . ALA B 1 156 ? 6.549   -23.320 -19.822 1.00 46.09  ? 156 ALA B CA  1 
ATOM   4813  C C   . ALA B 1 156 ? 7.666   -22.284 -19.917 1.00 45.71  ? 156 ALA B C   1 
ATOM   4814  O O   . ALA B 1 156 ? 7.882   -21.693 -20.969 1.00 41.34  ? 156 ALA B O   1 
ATOM   4815  C CB  . ALA B 1 156 ? 5.296   -22.694 -19.264 1.00 45.02  ? 156 ALA B CB  1 
ATOM   4816  N N   . LYS B 1 157 ? 8.360   -22.064 -18.798 1.00 45.67  ? 157 LYS B N   1 
ATOM   4817  C CA  . LYS B 1 157 ? 9.463   -21.122 -18.758 1.00 51.21  ? 157 LYS B CA  1 
ATOM   4818  C C   . LYS B 1 157 ? 10.587  -21.558 -19.703 1.00 44.26  ? 157 LYS B C   1 
ATOM   4819  O O   . LYS B 1 157 ? 10.967  -20.791 -20.580 1.00 44.21  ? 157 LYS B O   1 
ATOM   4820  C CB  . LYS B 1 157 ? 9.993   -20.993 -17.332 1.00 54.05  ? 157 LYS B CB  1 
ATOM   4821  C CG  . LYS B 1 157 ? 10.832  -19.753 -17.064 1.00 61.96  ? 157 LYS B CG  1 
ATOM   4822  C CD  . LYS B 1 157 ? 11.452  -19.747 -15.668 1.00 73.78  ? 157 LYS B CD  1 
ATOM   4823  C CE  . LYS B 1 157 ? 12.408  -18.591 -15.441 1.00 86.65  ? 157 LYS B CE  1 
ATOM   4824  N NZ  . LYS B 1 157 ? 13.442  -18.912 -14.426 1.00 88.03  ? 157 LYS B NZ  1 
ATOM   4825  N N   . ARG B 1 158 ? 11.131  -22.766 -19.523 1.00 47.73  ? 158 ARG B N   1 
ATOM   4826  C CA  . ARG B 1 158 ? 12.246  -23.215 -20.356 1.00 53.45  ? 158 ARG B CA  1 
ATOM   4827  C C   . ARG B 1 158 ? 11.856  -23.283 -21.840 1.00 54.80  ? 158 ARG B C   1 
ATOM   4828  O O   . ARG B 1 158 ? 12.689  -22.962 -22.689 1.00 52.07  ? 158 ARG B O   1 
ATOM   4829  C CB  . ARG B 1 158 ? 12.889  -24.485 -19.793 1.00 63.02  ? 158 ARG B CB  1 
ATOM   4830  C CG  . ARG B 1 158 ? 14.011  -24.169 -18.803 1.00 73.74  ? 158 ARG B CG  1 
ATOM   4831  C CD  . ARG B 1 158 ? 15.108  -25.215 -18.637 1.00 82.11  ? 158 ARG B CD  1 
ATOM   4832  N NE  . ARG B 1 158 ? 14.797  -26.209 -17.597 1.00 97.04  ? 158 ARG B NE  1 
ATOM   4833  C CZ  . ARG B 1 158 ? 15.099  -27.516 -17.649 1.00 93.85  ? 158 ARG B CZ  1 
ATOM   4834  N NH1 . ARG B 1 158 ? 14.728  -28.330 -16.666 1.00 62.20  ? 158 ARG B NH1 1 
ATOM   4835  N NH2 . ARG B 1 158 ? 15.765  -28.004 -18.691 1.00 94.12  ? 158 ARG B NH2 1 
ATOM   4836  N N   . TYR B 1 159 ? 10.584  -23.577 -22.162 1.00 48.51  ? 159 TYR B N   1 
ATOM   4837  C CA  . TYR B 1 159 ? 10.154  -23.556 -23.546 1.00 47.62  ? 159 TYR B CA  1 
ATOM   4838  C C   . TYR B 1 159 ? 10.246  -22.153 -24.156 1.00 55.77  ? 159 TYR B C   1 
ATOM   4839  O O   . TYR B 1 159 ? 10.723  -22.013 -25.295 1.00 46.94  ? 159 TYR B O   1 
ATOM   4840  C CB  . TYR B 1 159 ? 8.736   -24.113 -23.712 1.00 55.16  ? 159 TYR B CB  1 
ATOM   4841  C CG  . TYR B 1 159 ? 8.398   -24.330 -25.167 1.00 55.91  ? 159 TYR B CG  1 
ATOM   4842  C CD1 . TYR B 1 159 ? 8.687   -25.529 -25.807 1.00 55.68  ? 159 TYR B CD1 1 
ATOM   4843  C CD2 . TYR B 1 159 ? 7.927   -23.276 -25.941 1.00 52.80  ? 159 TYR B CD2 1 
ATOM   4844  C CE1 . TYR B 1 159 ? 8.438   -25.695 -27.165 1.00 54.93  ? 159 TYR B CE1 1 
ATOM   4845  C CE2 . TYR B 1 159 ? 7.681   -23.420 -27.294 1.00 55.12  ? 159 TYR B CE2 1 
ATOM   4846  C CZ  . TYR B 1 159 ? 7.931   -24.638 -27.909 1.00 59.60  ? 159 TYR B CZ  1 
ATOM   4847  O OH  . TYR B 1 159 ? 7.656   -24.760 -29.261 1.00 65.22  ? 159 TYR B OH  1 
ATOM   4848  N N   . GLU B 1 160 ? 9.731   -21.126 -23.446 1.00 55.78  ? 160 GLU B N   1 
ATOM   4849  C CA  . GLU B 1 160 ? 9.828   -19.742 -23.907 1.00 62.31  ? 160 GLU B CA  1 
ATOM   4850  C C   . GLU B 1 160 ? 11.308  -19.360 -24.041 1.00 68.51  ? 160 GLU B C   1 
ATOM   4851  O O   . GLU B 1 160 ? 11.640  -18.554 -24.914 1.00 54.27  ? 160 GLU B O   1 
ATOM   4852  C CB  . GLU B 1 160 ? 9.115   -18.717 -22.999 1.00 65.68  ? 160 GLU B CB  1 
ATOM   4853  C CG  . GLU B 1 160 ? 7.589   -18.634 -23.162 1.00 84.60  ? 160 GLU B CG  1 
ATOM   4854  C CD  . GLU B 1 160 ? 6.774   -17.853 -22.112 1.00 101.91 ? 160 GLU B CD  1 
ATOM   4855  O OE1 . GLU B 1 160 ? 5.855   -17.070 -22.511 1.00 93.60  ? 160 GLU B OE1 1 
ATOM   4856  O OE2 . GLU B 1 160 ? 7.018   -18.026 -20.878 1.00 84.07  ? 160 GLU B OE2 1 
ATOM   4857  N N   . GLU B 1 161 ? 12.181  -19.919 -23.171 1.00 63.01  ? 161 GLU B N   1 
ATOM   4858  C CA  . GLU B 1 161 ? 13.595  -19.563 -23.153 1.00 63.33  ? 161 GLU B CA  1 
ATOM   4859  C C   . GLU B 1 161 ? 14.329  -20.195 -24.333 1.00 65.06  ? 161 GLU B C   1 
ATOM   4860  O O   . GLU B 1 161 ? 15.393  -19.722 -24.694 1.00 66.35  ? 161 GLU B O   1 
ATOM   4861  C CB  . GLU B 1 161 ? 14.288  -19.995 -21.855 1.00 67.61  ? 161 GLU B CB  1 
ATOM   4862  C CG  . GLU B 1 161 ? 14.012  -19.074 -20.656 1.00 69.75  ? 161 GLU B CG  1 
ATOM   4863  C CD  . GLU B 1 161 ? 14.552  -19.546 -19.305 1.00 67.73  ? 161 GLU B CD  1 
ATOM   4864  O OE1 . GLU B 1 161 ? 14.441  -18.780 -18.317 1.00 64.45  ? 161 GLU B OE1 1 
ATOM   4865  O OE2 . GLU B 1 161 ? 15.080  -20.674 -19.231 1.00 64.25  ? 161 GLU B OE2 1 
ATOM   4866  N N   . GLY B 1 162 ? 13.766  -21.266 -24.911 1.00 71.13  ? 162 GLY B N   1 
ATOM   4867  C CA  . GLY B 1 162 ? 14.486  -22.138 -25.825 1.00 67.87  ? 162 GLY B CA  1 
ATOM   4868  C C   . GLY B 1 162 ? 15.176  -23.282 -25.079 1.00 66.45  ? 162 GLY B C   1 
ATOM   4869  O O   . GLY B 1 162 ? 16.148  -23.077 -24.360 1.00 76.11  ? 162 GLY B O   1 
ATOM   4870  N N   . MET B 1 163 ? 14.621  -24.484 -25.197 1.00 59.19  ? 163 MET B N   1 
ATOM   4871  C CA  . MET B 1 163 ? 15.284  -25.679 -24.717 1.00 57.79  ? 163 MET B CA  1 
ATOM   4872  C C   . MET B 1 163 ? 15.139  -26.733 -25.819 1.00 61.01  ? 163 MET B C   1 
ATOM   4873  O O   . MET B 1 163 ? 14.258  -26.646 -26.662 1.00 52.34  ? 163 MET B O   1 
ATOM   4874  C CB  . MET B 1 163 ? 14.698  -26.186 -23.388 1.00 56.66  ? 163 MET B CB  1 
ATOM   4875  C CG  . MET B 1 163 ? 13.299  -26.834 -23.493 1.00 54.50  ? 163 MET B CG  1 
ATOM   4876  S SD  . MET B 1 163 ? 12.682  -27.624 -21.955 1.00 50.84  ? 163 MET B SD  1 
ATOM   4877  C CE  . MET B 1 163 ? 10.922  -27.352 -22.114 1.00 52.67  ? 163 MET B CE  1 
ATOM   4878  N N   . ARG B 1 164 ? 16.044  -27.704 -25.834 1.00 74.38  ? 164 ARG B N   1 
ATOM   4879  C CA  . ARG B 1 164 ? 15.991  -28.797 -26.791 1.00 86.23  ? 164 ARG B CA  1 
ATOM   4880  C C   . ARG B 1 164 ? 14.887  -29.767 -26.373 1.00 70.31  ? 164 ARG B C   1 
ATOM   4881  O O   . ARG B 1 164 ? 14.678  -29.986 -25.182 1.00 49.92  ? 164 ARG B O   1 
ATOM   4882  C CB  . ARG B 1 164 ? 17.356  -29.496 -26.838 1.00 99.03  ? 164 ARG B CB  1 
ATOM   4883  C CG  . ARG B 1 164 ? 18.425  -28.748 -27.627 1.00 109.88 ? 164 ARG B CG  1 
ATOM   4884  C CD  . ARG B 1 164 ? 19.840  -29.050 -27.149 1.00 114.59 ? 164 ARG B CD  1 
ATOM   4885  N NE  . ARG B 1 164 ? 20.006  -30.392 -26.589 1.00 122.87 ? 164 ARG B NE  1 
ATOM   4886  C CZ  . ARG B 1 164 ? 20.039  -31.531 -27.285 1.00 119.41 ? 164 ARG B CZ  1 
ATOM   4887  N NH1 . ARG B 1 164 ? 19.959  -31.513 -28.606 1.00 119.11 ? 164 ARG B NH1 1 
ATOM   4888  N NH2 . ARG B 1 164 ? 20.167  -32.689 -26.651 1.00 99.54  ? 164 ARG B NH2 1 
ATOM   4889  N N   . ARG B 1 165 ? 14.242  -30.388 -27.367 1.00 71.29  ? 165 ARG B N   1 
ATOM   4890  C CA  . ARG B 1 165 ? 13.154  -31.333 -27.143 1.00 67.42  ? 165 ARG B CA  1 
ATOM   4891  C C   . ARG B 1 165 ? 13.618  -32.437 -26.186 1.00 62.35  ? 165 ARG B C   1 
ATOM   4892  O O   . ARG B 1 165 ? 12.818  -33.027 -25.454 1.00 56.10  ? 165 ARG B O   1 
ATOM   4893  C CB  . ARG B 1 165 ? 12.665  -31.893 -28.482 1.00 71.47  ? 165 ARG B CB  1 
ATOM   4894  C CG  . ARG B 1 165 ? 12.203  -30.847 -29.489 1.00 82.76  ? 165 ARG B CG  1 
ATOM   4895  C CD  . ARG B 1 165 ? 12.099  -31.408 -30.901 1.00 94.02  ? 165 ARG B CD  1 
ATOM   4896  N NE  . ARG B 1 165 ? 10.949  -32.296 -31.086 1.00 96.23  ? 165 ARG B NE  1 
ATOM   4897  C CZ  . ARG B 1 165 ? 10.923  -33.398 -31.848 1.00 92.97  ? 165 ARG B CZ  1 
ATOM   4898  N NH1 . ARG B 1 165 ? 11.997  -33.775 -32.525 1.00 91.35  ? 165 ARG B NH1 1 
ATOM   4899  N NH2 . ARG B 1 165 ? 9.812   -34.117 -31.946 1.00 68.01  ? 165 ARG B NH2 1 
ATOM   4900  N N   . GLU B 1 166 ? 14.936  -32.656 -26.160 1.00 56.75  ? 166 GLU B N   1 
ATOM   4901  C CA  . GLU B 1 166 ? 15.569  -33.706 -25.377 1.00 61.21  ? 166 GLU B CA  1 
ATOM   4902  C C   . GLU B 1 166 ? 15.449  -33.385 -23.891 1.00 57.21  ? 166 GLU B C   1 
ATOM   4903  O O   . GLU B 1 166 ? 15.537  -34.281 -23.066 1.00 53.40  ? 166 GLU B O   1 
ATOM   4904  C CB  . GLU B 1 166 ? 17.039  -33.857 -25.802 1.00 67.51  ? 166 GLU B CB  1 
ATOM   4905  C CG  . GLU B 1 166 ? 17.239  -34.572 -27.150 1.00 78.80  ? 166 GLU B CG  1 
ATOM   4906  C CD  . GLU B 1 166 ? 16.934  -33.841 -28.464 1.00 85.07  ? 166 GLU B CD  1 
ATOM   4907  O OE1 . GLU B 1 166 ? 17.115  -34.468 -29.542 1.00 85.94  ? 166 GLU B OE1 1 
ATOM   4908  O OE2 . GLU B 1 166 ? 16.518  -32.656 -28.441 1.00 79.91  ? 166 GLU B OE2 1 
ATOM   4909  N N   . GLU B 1 167 ? 15.262  -32.100 -23.574 1.00 54.57  ? 167 GLU B N   1 
ATOM   4910  C CA  . GLU B 1 167 ? 15.108  -31.631 -22.209 1.00 62.55  ? 167 GLU B CA  1 
ATOM   4911  C C   . GLU B 1 167 ? 13.638  -31.652 -21.775 1.00 53.49  ? 167 GLU B C   1 
ATOM   4912  O O   . GLU B 1 167 ? 13.377  -31.517 -20.594 1.00 51.05  ? 167 GLU B O   1 
ATOM   4913  C CB  . GLU B 1 167 ? 15.598  -30.187 -22.070 1.00 71.18  ? 167 GLU B CB  1 
ATOM   4914  C CG  . GLU B 1 167 ? 17.108  -29.964 -22.155 1.00 86.17  ? 167 GLU B CG  1 
ATOM   4915  C CD  . GLU B 1 167 ? 17.484  -28.483 -22.067 1.00 92.27  ? 167 GLU B CD  1 
ATOM   4916  O OE1 . GLU B 1 167 ? 17.115  -27.814 -21.042 1.00 83.04  ? 167 GLU B OE1 1 
ATOM   4917  O OE2 . GLU B 1 167 ? 18.073  -27.964 -23.054 1.00 70.72  ? 167 GLU B OE2 1 
ATOM   4918  N N   . HIS B 1 168 ? 12.682  -31.837 -22.702 1.00 42.81  ? 168 HIS B N   1 
ATOM   4919  C CA  . HIS B 1 168 ? 11.275  -31.818 -22.330 1.00 43.47  ? 168 HIS B CA  1 
ATOM   4920  C C   . HIS B 1 168 ? 11.017  -32.663 -21.091 1.00 40.40  ? 168 HIS B C   1 
ATOM   4921  O O   . HIS B 1 168 ? 10.433  -32.188 -20.125 1.00 45.40  ? 168 HIS B O   1 
ATOM   4922  C CB  . HIS B 1 168 ? 10.343  -32.184 -23.488 1.00 40.43  ? 168 HIS B CB  1 
ATOM   4923  C CG  . HIS B 1 168 ? 10.304  -31.120 -24.531 1.00 47.73  ? 168 HIS B CG  1 
ATOM   4924  N ND1 . HIS B 1 168 ? 9.506   -31.178 -25.652 1.00 47.57  ? 168 HIS B ND1 1 
ATOM   4925  C CD2 . HIS B 1 168 ? 10.968  -29.943 -24.599 1.00 46.27  ? 168 HIS B CD2 1 
ATOM   4926  C CE1 . HIS B 1 168 ? 9.730   -30.093 -26.382 1.00 51.30  ? 168 HIS B CE1 1 
ATOM   4927  N NE2 . HIS B 1 168 ? 10.601  -29.328 -25.758 1.00 47.88  ? 168 HIS B NE2 1 
ATOM   4928  N N   . TRP B 1 169 ? 11.459  -33.906 -21.094 1.00 42.32  ? 169 TRP B N   1 
ATOM   4929  C CA  . TRP B 1 169 ? 11.089  -34.832 -20.034 1.00 42.21  ? 169 TRP B CA  1 
ATOM   4930  C C   . TRP B 1 169 ? 11.618  -34.375 -18.671 1.00 43.87  ? 169 TRP B C   1 
ATOM   4931  O O   . TRP B 1 169 ? 11.033  -34.732 -17.646 1.00 43.91  ? 169 TRP B O   1 
ATOM   4932  C CB  . TRP B 1 169 ? 11.532  -36.256 -20.372 1.00 44.27  ? 169 TRP B CB  1 
ATOM   4933  C CG  . TRP B 1 169 ? 13.019  -36.469 -20.337 1.00 50.36  ? 169 TRP B CG  1 
ATOM   4934  C CD1 . TRP B 1 169 ? 13.889  -36.450 -21.398 1.00 49.13  ? 169 TRP B CD1 1 
ATOM   4935  C CD2 . TRP B 1 169 ? 13.807  -36.800 -19.179 1.00 50.44  ? 169 TRP B CD2 1 
ATOM   4936  N NE1 . TRP B 1 169 ? 15.166  -36.698 -20.969 1.00 52.18  ? 169 TRP B NE1 1 
ATOM   4937  C CE2 . TRP B 1 169 ? 15.148  -36.920 -19.617 1.00 49.85  ? 169 TRP B CE2 1 
ATOM   4938  C CE3 . TRP B 1 169 ? 13.514  -36.961 -17.817 1.00 49.83  ? 169 TRP B CE3 1 
ATOM   4939  C CZ2 . TRP B 1 169 ? 16.185  -37.218 -18.743 1.00 53.65  ? 169 TRP B CZ2 1 
ATOM   4940  C CZ3 . TRP B 1 169 ? 14.543  -37.253 -16.953 1.00 51.32  ? 169 TRP B CZ3 1 
ATOM   4941  C CH2 . TRP B 1 169 ? 15.858  -37.387 -17.412 1.00 54.76  ? 169 TRP B CH2 1 
ATOM   4942  N N   . GLU B 1 170 ? 12.735  -33.635 -18.634 1.00 47.77  ? 170 GLU B N   1 
ATOM   4943  C CA  . GLU B 1 170 ? 13.306  -33.216 -17.352 1.00 56.94  ? 170 GLU B CA  1 
ATOM   4944  C C   . GLU B 1 170 ? 12.459  -32.106 -16.729 1.00 51.31  ? 170 GLU B C   1 
ATOM   4945  O O   . GLU B 1 170 ? 12.127  -32.125 -15.544 1.00 47.53  ? 170 GLU B O   1 
ATOM   4946  C CB  . GLU B 1 170 ? 14.739  -32.705 -17.501 1.00 55.74  ? 170 GLU B CB  1 
ATOM   4947  C CG  . GLU B 1 170 ? 15.720  -33.781 -17.945 1.00 63.82  ? 170 GLU B CG  1 
ATOM   4948  C CD  . GLU B 1 170 ? 17.156  -33.294 -18.071 1.00 66.19  ? 170 GLU B CD  1 
ATOM   4949  O OE1 . GLU B 1 170 ? 17.666  -33.271 -19.193 1.00 71.48  ? 170 GLU B OE1 1 
ATOM   4950  O OE2 . GLU B 1 170 ? 17.745  -32.908 -17.046 1.00 72.49  ? 170 GLU B OE2 1 
ATOM   4951  N N   . ALA B 1 171 ? 12.104  -31.129 -17.554 1.00 46.20  ? 171 ALA B N   1 
ATOM   4952  C CA  . ALA B 1 171 ? 11.240  -30.061 -17.091 1.00 44.11  ? 171 ALA B CA  1 
ATOM   4953  C C   . ALA B 1 171 ? 9.897   -30.645 -16.642 1.00 42.16  ? 171 ALA B C   1 
ATOM   4954  O O   . ALA B 1 171 ? 9.337   -30.214 -15.628 1.00 40.89  ? 171 ALA B O   1 
ATOM   4955  C CB  . ALA B 1 171 ? 11.113  -29.013 -18.170 1.00 41.07  ? 171 ALA B CB  1 
ATOM   4956  N N   . MET B 1 172 ? 9.407   -31.662 -17.359 1.00 41.61  ? 172 MET B N   1 
ATOM   4957  C CA  . MET B 1 172 ? 8.134   -32.272 -17.016 1.00 39.95  ? 172 MET B CA  1 
ATOM   4958  C C   . MET B 1 172 ? 8.246   -32.968 -15.668 1.00 39.70  ? 172 MET B C   1 
ATOM   4959  O O   . MET B 1 172 ? 7.282   -33.042 -14.913 1.00 38.56  ? 172 MET B O   1 
ATOM   4960  C CB  . MET B 1 172 ? 7.726   -33.292 -18.072 1.00 43.13  ? 172 MET B CB  1 
ATOM   4961  C CG  . MET B 1 172 ? 7.139   -32.634 -19.306 1.00 45.95  ? 172 MET B CG  1 
ATOM   4962  S SD  . MET B 1 172 ? 5.423   -32.164 -19.046 1.00 46.73  ? 172 MET B SD  1 
ATOM   4963  C CE  . MET B 1 172 ? 5.255   -31.053 -20.430 1.00 55.36  ? 172 MET B CE  1 
ATOM   4964  N N   . LEU B 1 173 ? 9.429   -33.491 -15.370 1.00 42.91  ? 173 LEU B N   1 
ATOM   4965  C CA  . LEU B 1 173 ? 9.597   -34.221 -14.130 1.00 48.42  ? 173 LEU B CA  1 
ATOM   4966  C C   . LEU B 1 173 ? 9.555   -33.247 -12.966 1.00 41.52  ? 173 LEU B C   1 
ATOM   4967  O O   . LEU B 1 173 ? 8.837   -33.478 -12.015 1.00 45.50  ? 173 LEU B O   1 
ATOM   4968  C CB  . LEU B 1 173 ? 10.904  -35.003 -14.149 1.00 48.41  ? 173 LEU B CB  1 
ATOM   4969  C CG  . LEU B 1 173 ? 11.246  -35.671 -12.822 1.00 51.53  ? 173 LEU B CG  1 
ATOM   4970  C CD1 . LEU B 1 173 ? 10.225  -36.722 -12.471 1.00 43.70  ? 173 LEU B CD1 1 
ATOM   4971  C CD2 . LEU B 1 173 ? 12.666  -36.258 -12.859 1.00 55.90  ? 173 LEU B CD2 1 
ATOM   4972  N N   . GLU B 1 174 ? 10.334  -32.174 -13.043 1.00 50.73  ? 174 GLU B N   1 
ATOM   4973  C CA  . GLU B 1 174 ? 10.345  -31.142 -12.010 1.00 55.40  ? 174 GLU B CA  1 
ATOM   4974  C C   . GLU B 1 174 ? 8.921   -30.609 -11.746 1.00 46.64  ? 174 GLU B C   1 
ATOM   4975  O O   . GLU B 1 174 ? 8.425   -30.637 -10.625 1.00 39.40  ? 174 GLU B O   1 
ATOM   4976  C CB  . GLU B 1 174 ? 11.309  -30.031 -12.439 1.00 64.32  ? 174 GLU B CB  1 
ATOM   4977  C CG  . GLU B 1 174 ? 11.735  -29.090 -11.305 1.00 73.64  ? 174 GLU B CG  1 
ATOM   4978  C CD  . GLU B 1 174 ? 12.814  -29.626 -10.377 1.00 76.72  ? 174 GLU B CD  1 
ATOM   4979  O OE1 . GLU B 1 174 ? 13.311  -30.766 -10.610 1.00 80.06  ? 174 GLU B OE1 1 
ATOM   4980  O OE2 . GLU B 1 174 ? 13.170  -28.891 -9.435  1.00 85.98  ? 174 GLU B OE2 1 
ATOM   4981  N N   . ASP B 1 175 ? 8.248   -30.120 -12.788 1.00 40.62  ? 175 ASP B N   1 
ATOM   4982  C CA  . ASP B 1 175 ? 6.871   -29.677 -12.662 1.00 37.01  ? 175 ASP B CA  1 
ATOM   4983  C C   . ASP B 1 175 ? 5.991   -30.718 -11.967 1.00 37.10  ? 175 ASP B C   1 
ATOM   4984  O O   . ASP B 1 175 ? 5.195   -30.334 -11.108 1.00 41.79  ? 175 ASP B O   1 
ATOM   4985  C CB  . ASP B 1 175 ? 6.286   -29.298 -14.008 1.00 31.06  ? 175 ASP B CB  1 
ATOM   4986  C CG  . ASP B 1 175 ? 6.755   -27.941 -14.471 1.00 37.12  ? 175 ASP B CG  1 
ATOM   4987  O OD1 . ASP B 1 175 ? 7.355   -27.191 -13.643 1.00 47.81  ? 175 ASP B OD1 1 
ATOM   4988  O OD2 . ASP B 1 175 ? 6.521   -27.625 -15.642 1.00 39.88  ? 175 ASP B OD2 1 
ATOM   4989  N N   . SER B 1 176 ? 6.181   -32.016 -12.273 1.00 35.28  ? 176 SER B N   1 
ATOM   4990  C CA  . SER B 1 176 ? 5.398   -33.116 -11.716 1.00 32.47  ? 176 SER B CA  1 
ATOM   4991  C C   . SER B 1 176 ? 5.644   -33.314 -10.225 1.00 31.15  ? 176 SER B C   1 
ATOM   4992  O O   . SER B 1 176 ? 4.720   -33.580 -9.471  1.00 38.43  ? 176 SER B O   1 
ATOM   4993  C CB  . SER B 1 176 ? 5.624   -34.407 -12.471 1.00 34.98  ? 176 SER B CB  1 
ATOM   4994  O OG  . SER B 1 176 ? 5.201   -34.291 -13.823 1.00 38.87  ? 176 SER B OG  1 
ATOM   4995  N N   . LEU B 1 177 ? 6.900   -33.250 -9.809  1.00 36.10  ? 177 LEU B N   1 
ATOM   4996  C CA  . LEU B 1 177 ? 7.255   -33.278 -8.402  1.00 38.80  ? 177 LEU B CA  1 
ATOM   4997  C C   . LEU B 1 177 ? 6.557   -32.134 -7.670  1.00 36.29  ? 177 LEU B C   1 
ATOM   4998  O O   . LEU B 1 177 ? 5.980   -32.329 -6.613  1.00 38.70  ? 177 LEU B O   1 
ATOM   4999  C CB  . LEU B 1 177 ? 8.784   -33.127 -8.289  1.00 43.64  ? 177 LEU B CB  1 
ATOM   5000  C CG  . LEU B 1 177 ? 9.639   -34.322 -8.735  1.00 43.88  ? 177 LEU B CG  1 
ATOM   5001  C CD1 . LEU B 1 177 ? 11.120  -33.954 -8.752  1.00 48.86  ? 177 LEU B CD1 1 
ATOM   5002  C CD2 . LEU B 1 177 ? 9.423   -35.517 -7.829  1.00 40.74  ? 177 LEU B CD2 1 
ATOM   5003  N N   . ASN B 1 178 ? 6.622   -30.926 -8.227  1.00 36.19  ? 178 ASN B N   1 
ATOM   5004  C CA  . ASN B 1 178 ? 5.972   -29.780 -7.612  1.00 40.40  ? 178 ASN B CA  1 
ATOM   5005  C C   . ASN B 1 178 ? 4.458   -30.000 -7.533  1.00 40.91  ? 178 ASN B C   1 
ATOM   5006  O O   . ASN B 1 178 ? 3.817   -29.812 -6.494  1.00 41.26  ? 178 ASN B O   1 
ATOM   5007  C CB  . ASN B 1 178 ? 6.336   -28.502 -8.375  1.00 39.88  ? 178 ASN B CB  1 
ATOM   5008  C CG  . ASN B 1 178 ? 7.757   -28.097 -8.087  1.00 38.68  ? 178 ASN B CG  1 
ATOM   5009  O OD1 . ASN B 1 178 ? 8.349   -28.531 -7.100  1.00 41.89  ? 178 ASN B OD1 1 
ATOM   5010  N ND2 . ASN B 1 178 ? 8.326   -27.303 -8.963  1.00 38.03  ? 178 ASN B ND2 1 
ATOM   5011  N N   . MET B 1 179 ? 3.878   -30.440 -8.643  1.00 37.46  ? 179 MET B N   1 
ATOM   5012  C CA  . MET B 1 179 ? 2.436   -30.464 -8.699  1.00 39.60  ? 179 MET B CA  1 
ATOM   5013  C C   . MET B 1 179 ? 1.920   -31.533 -7.742  1.00 37.49  ? 179 MET B C   1 
ATOM   5014  O O   . MET B 1 179 ? 0.936   -31.290 -7.054  1.00 35.23  ? 179 MET B O   1 
ATOM   5015  C CB  . MET B 1 179 ? 1.913   -30.700 -10.117 1.00 37.23  ? 179 MET B CB  1 
ATOM   5016  C CG  . MET B 1 179 ? 0.428   -30.510 -10.191 1.00 37.23  ? 179 MET B CG  1 
ATOM   5017  S SD  . MET B 1 179 ? -0.276  -30.995 -11.770 1.00 41.03  ? 179 MET B SD  1 
ATOM   5018  C CE  . MET B 1 179 ? -0.298  -32.759 -11.439 1.00 38.45  ? 179 MET B CE  1 
ATOM   5019  N N   . LEU B 1 180 ? 2.579   -32.696 -7.705  1.00 37.71  ? 180 LEU B N   1 
ATOM   5020  C CA  . LEU B 1 180 ? 2.049   -33.818 -6.932  1.00 39.26  ? 180 LEU B CA  1 
ATOM   5021  C C   . LEU B 1 180 ? 2.147   -33.493 -5.442  1.00 40.72  ? 180 LEU B C   1 
ATOM   5022  O O   . LEU B 1 180 ? 1.309   -33.911 -4.651  1.00 42.30  ? 180 LEU B O   1 
ATOM   5023  C CB  . LEU B 1 180 ? 2.860   -35.077 -7.255  1.00 41.71  ? 180 LEU B CB  1 
ATOM   5024  C CG  . LEU B 1 180 ? 2.558   -35.780 -8.579  1.00 39.63  ? 180 LEU B CG  1 
ATOM   5025  C CD1 . LEU B 1 180 ? 3.631   -36.813 -8.892  1.00 36.53  ? 180 LEU B CD1 1 
ATOM   5026  C CD2 . LEU B 1 180 ? 1.184   -36.439 -8.542  1.00 38.17  ? 180 LEU B CD2 1 
ATOM   5027  N N   . ALA B 1 181 ? 3.210   -32.763 -5.063  1.00 41.91  ? 181 ALA B N   1 
ATOM   5028  C CA  . ALA B 1 181 ? 3.407   -32.367 -3.682  1.00 40.08  ? 181 ALA B CA  1 
ATOM   5029  C C   . ALA B 1 181 ? 2.256   -31.455 -3.268  1.00 38.83  ? 181 ALA B C   1 
ATOM   5030  O O   . ALA B 1 181 ? 1.831   -31.514 -2.146  1.00 30.99  ? 181 ALA B O   1 
ATOM   5031  C CB  . ALA B 1 181 ? 4.736   -31.669 -3.574  1.00 38.69  ? 181 ALA B CB  1 
ATOM   5032  N N   . ALA B 1 182 ? 1.788   -30.621 -4.213  1.00 39.26  ? 182 ALA B N   1 
ATOM   5033  C CA  . ALA B 1 182 ? 0.828   -29.569 -3.964  1.00 39.66  ? 182 ALA B CA  1 
ATOM   5034  C C   . ALA B 1 182 ? -0.565  -30.154 -3.820  1.00 38.31  ? 182 ALA B C   1 
ATOM   5035  O O   . ALA B 1 182 ? -1.312  -29.649 -2.994  1.00 42.50  ? 182 ALA B O   1 
ATOM   5036  C CB  . ALA B 1 182 ? 0.846   -28.527 -5.063  1.00 38.23  ? 182 ALA B CB  1 
ATOM   5037  N N   . LEU B 1 183 ? -0.864  -31.233 -4.566  1.00 37.39  ? 183 LEU B N   1 
ATOM   5038  C CA  . LEU B 1 183 ? -2.225  -31.726 -4.731  1.00 36.51  ? 183 LEU B CA  1 
ATOM   5039  C C   . LEU B 1 183 ? -2.900  -32.011 -3.401  1.00 33.81  ? 183 LEU B C   1 
ATOM   5040  O O   . LEU B 1 183 ? -4.057  -31.640 -3.228  1.00 39.12  ? 183 LEU B O   1 
ATOM   5041  C CB  . LEU B 1 183 ? -2.260  -32.958 -5.625  1.00 33.77  ? 183 LEU B CB  1 
ATOM   5042  C CG  . LEU B 1 183 ? -2.040  -32.708 -7.115  1.00 36.60  ? 183 LEU B CG  1 
ATOM   5043  C CD1 . LEU B 1 183 ? -2.398  -33.941 -7.902  1.00 37.83  ? 183 LEU B CD1 1 
ATOM   5044  C CD2 . LEU B 1 183 ? -2.865  -31.560 -7.628  1.00 37.09  ? 183 LEU B CD2 1 
ATOM   5045  N N   . PRO B 1 184 ? -2.283  -32.729 -2.450  1.00 33.83  ? 184 PRO B N   1 
ATOM   5046  C CA  . PRO B 1 184 ? -2.942  -33.009 -1.171  1.00 35.93  ? 184 PRO B CA  1 
ATOM   5047  C C   . PRO B 1 184 ? -3.117  -31.738 -0.344  1.00 34.38  ? 184 PRO B C   1 
ATOM   5048  O O   . PRO B 1 184 ? -4.041  -31.630 0.441   1.00 38.39  ? 184 PRO B O   1 
ATOM   5049  C CB  . PRO B 1 184 ? -1.988  -33.935 -0.412  1.00 34.58  ? 184 PRO B CB  1 
ATOM   5050  C CG  . PRO B 1 184 ? -0.929  -34.338 -1.398  1.00 37.39  ? 184 PRO B CG  1 
ATOM   5051  C CD  . PRO B 1 184 ? -0.970  -33.363 -2.548  1.00 37.79  ? 184 PRO B CD  1 
ATOM   5052  N N   . VAL B 1 185 ? -2.273  -30.733 -0.593  1.00 37.92  ? 185 VAL B N   1 
ATOM   5053  C CA  . VAL B 1 185 ? -2.420  -29.452 0.079   1.00 37.57  ? 185 VAL B CA  1 
ATOM   5054  C C   . VAL B 1 185 ? -3.648  -28.720 -0.449  1.00 37.17  ? 185 VAL B C   1 
ATOM   5055  O O   . VAL B 1 185 ? -4.452  -28.234 0.346   1.00 34.70  ? 185 VAL B O   1 
ATOM   5056  C CB  . VAL B 1 185 ? -1.129  -28.622 0.010   1.00 43.26  ? 185 VAL B CB  1 
ATOM   5057  C CG1 . VAL B 1 185 ? -1.304  -27.274 0.697   1.00 41.81  ? 185 VAL B CG1 1 
ATOM   5058  C CG2 . VAL B 1 185 ? 0.039   -29.401 0.632   1.00 44.33  ? 185 VAL B CG2 1 
ATOM   5059  N N   . ILE B 1 186 ? -3.806  -28.679 -1.770  1.00 31.85  ? 186 ILE B N   1 
ATOM   5060  C CA  . ILE B 1 186 ? -4.935  -28.002 -2.390  1.00 32.17  ? 186 ILE B CA  1 
ATOM   5061  C C   . ILE B 1 186 ? -6.217  -28.723 -2.011  1.00 32.06  ? 186 ILE B C   1 
ATOM   5062  O O   . ILE B 1 186 ? -7.192  -28.092 -1.577  1.00 31.46  ? 186 ILE B O   1 
ATOM   5063  C CB  . ILE B 1 186 ? -4.697  -27.930 -3.911  1.00 37.12  ? 186 ILE B CB  1 
ATOM   5064  C CG1 . ILE B 1 186 ? -3.490  -27.050 -4.228  1.00 32.29  ? 186 ILE B CG1 1 
ATOM   5065  C CG2 . ILE B 1 186 ? -5.928  -27.486 -4.686  1.00 39.58  ? 186 ILE B CG2 1 
ATOM   5066  C CD1 . ILE B 1 186 ? -2.984  -27.180 -5.662  1.00 37.17  ? 186 ILE B CD1 1 
ATOM   5067  N N   . ALA B 1 187 ? -6.183  -30.063 -2.055  1.00 33.09  ? 187 ALA B N   1 
ATOM   5068  C CA  . ALA B 1 187 ? -7.368  -30.862 -1.775  1.00 30.68  ? 187 ALA B CA  1 
ATOM   5069  C C   . ALA B 1 187 ? -7.814  -30.715 -0.328  1.00 30.26  ? 187 ALA B C   1 
ATOM   5070  O O   . ALA B 1 187 ? -8.996  -30.573 -0.039  1.00 35.64  ? 187 ALA B O   1 
ATOM   5071  C CB  . ALA B 1 187 ? -7.124  -32.315 -2.087  1.00 31.15  ? 187 ALA B CB  1 
ATOM   5072  N N   . ALA B 1 188 ? -6.869  -30.770 0.592   1.00 32.52  ? 188 ALA B N   1 
ATOM   5073  C CA  . ALA B 1 188 ? -7.206  -30.638 1.992   1.00 30.79  ? 188 ALA B CA  1 
ATOM   5074  C C   . ALA B 1 188 ? -7.757  -29.243 2.258   1.00 30.27  ? 188 ALA B C   1 
ATOM   5075  O O   . ALA B 1 188 ? -8.747  -29.073 2.998   1.00 32.43  ? 188 ALA B O   1 
ATOM   5076  C CB  . ALA B 1 188 ? -5.976  -30.908 2.804   1.00 34.65  ? 188 ALA B CB  1 
ATOM   5077  N N   . TYR B 1 189 ? -7.126  -28.227 1.661   1.00 30.66  ? 189 TYR B N   1 
ATOM   5078  C CA  . TYR B 1 189 ? -7.640  -26.880 1.841   1.00 34.38  ? 189 TYR B CA  1 
ATOM   5079  C C   . TYR B 1 189 ? -9.136  -26.849 1.491   1.00 37.47  ? 189 TYR B C   1 
ATOM   5080  O O   . TYR B 1 189 ? -9.932  -26.264 2.222   1.00 34.03  ? 189 TYR B O   1 
ATOM   5081  C CB  . TYR B 1 189 ? -6.938  -25.866 0.944   1.00 38.10  ? 189 TYR B CB  1 
ATOM   5082  C CG  . TYR B 1 189 ? -7.208  -24.432 1.342   1.00 39.88  ? 189 TYR B CG  1 
ATOM   5083  C CD1 . TYR B 1 189 ? -6.500  -23.871 2.384   1.00 40.05  ? 189 TYR B CD1 1 
ATOM   5084  C CD2 . TYR B 1 189 ? -8.212  -23.678 0.763   1.00 39.50  ? 189 TYR B CD2 1 
ATOM   5085  C CE1 . TYR B 1 189 ? -6.720  -22.579 2.809   1.00 43.15  ? 189 TYR B CE1 1 
ATOM   5086  C CE2 . TYR B 1 189 ? -8.440  -22.373 1.168   1.00 39.88  ? 189 TYR B CE2 1 
ATOM   5087  C CZ  . TYR B 1 189 ? -7.703  -21.836 2.206   1.00 42.63  ? 189 TYR B CZ  1 
ATOM   5088  O OH  . TYR B 1 189 ? -7.819  -20.562 2.668   1.00 55.48  ? 189 TYR B OH  1 
ATOM   5089  N N   . ILE B 1 190 ? -9.492  -27.471 0.350   1.00 35.73  ? 190 ILE B N   1 
ATOM   5090  C CA  . ILE B 1 190 ? -10.857 -27.472 -0.149  1.00 33.78  ? 190 ILE B CA  1 
ATOM   5091  C C   . ILE B 1 190 ? -11.753 -28.164 0.869   1.00 34.39  ? 190 ILE B C   1 
ATOM   5092  O O   . ILE B 1 190 ? -12.798 -27.652 1.257   1.00 34.38  ? 190 ILE B O   1 
ATOM   5093  C CB  . ILE B 1 190 ? -10.951 -28.134 -1.535  1.00 31.74  ? 190 ILE B CB  1 
ATOM   5094  C CG1 . ILE B 1 190 ? -10.261 -27.263 -2.581  1.00 36.70  ? 190 ILE B CG1 1 
ATOM   5095  C CG2 . ILE B 1 190 ? -12.421 -28.411 -1.896  1.00 32.06  ? 190 ILE B CG2 1 
ATOM   5096  C CD1 . ILE B 1 190 ? -10.117 -27.940 -3.930  1.00 41.67  ? 190 ILE B CD1 1 
ATOM   5097  N N   . TYR B 1 191 ? -11.323 -29.352 1.287   1.00 36.74  ? 191 TYR B N   1 
ATOM   5098  C CA  . TYR B 1 191 ? -12.070 -30.125 2.260   1.00 38.11  ? 191 TYR B CA  1 
ATOM   5099  C C   . TYR B 1 191 ? -12.298 -29.289 3.521   1.00 32.90  ? 191 TYR B C   1 
ATOM   5100  O O   . TYR B 1 191 ? -13.402 -29.194 4.016   1.00 33.68  ? 191 TYR B O   1 
ATOM   5101  C CB  . TYR B 1 191 ? -11.307 -31.430 2.545   1.00 40.01  ? 191 TYR B CB  1 
ATOM   5102  C CG  . TYR B 1 191 ? -12.080 -32.437 3.352   1.00 35.49  ? 191 TYR B CG  1 
ATOM   5103  C CD1 . TYR B 1 191 ? -13.076 -33.197 2.786   1.00 38.74  ? 191 TYR B CD1 1 
ATOM   5104  C CD2 . TYR B 1 191 ? -11.865 -32.564 4.704   1.00 40.40  ? 191 TYR B CD2 1 
ATOM   5105  C CE1 . TYR B 1 191 ? -13.808 -34.092 3.542   1.00 44.69  ? 191 TYR B CE1 1 
ATOM   5106  C CE2 . TYR B 1 191 ? -12.571 -33.470 5.471   1.00 40.07  ? 191 TYR B CE2 1 
ATOM   5107  C CZ  . TYR B 1 191 ? -13.554 -34.229 4.895   1.00 42.56  ? 191 TYR B CZ  1 
ATOM   5108  O OH  . TYR B 1 191 ? -14.258 -35.090 5.712   1.00 44.37  ? 191 TYR B OH  1 
ATOM   5109  N N   . ARG B 1 192 ? -11.236 -28.704 4.073   1.00 33.61  ? 192 ARG B N   1 
ATOM   5110  C CA  . ARG B 1 192 ? -11.381 -28.023 5.343   1.00 36.98  ? 192 ARG B CA  1 
ATOM   5111  C C   . ARG B 1 192 ? -12.270 -26.791 5.204   1.00 37.20  ? 192 ARG B C   1 
ATOM   5112  O O   . ARG B 1 192 ? -13.099 -26.513 6.066   1.00 36.10  ? 192 ARG B O   1 
ATOM   5113  C CB  . ARG B 1 192 ? -10.028 -27.587 5.924   1.00 34.69  ? 192 ARG B CB  1 
ATOM   5114  C CG  . ARG B 1 192 ? -9.085  -28.737 6.224   1.00 34.60  ? 192 ARG B CG  1 
ATOM   5115  C CD  . ARG B 1 192 ? -9.679  -29.690 7.209   1.00 35.14  ? 192 ARG B CD  1 
ATOM   5116  N NE  . ARG B 1 192 ? -9.741  -29.057 8.499   1.00 34.32  ? 192 ARG B NE  1 
ATOM   5117  C CZ  . ARG B 1 192 ? -10.157 -29.670 9.580   1.00 35.00  ? 192 ARG B CZ  1 
ATOM   5118  N NH1 . ARG B 1 192 ? -10.497 -30.946 9.517   1.00 36.00  ? 192 ARG B NH1 1 
ATOM   5119  N NH2 . ARG B 1 192 ? -10.243 -29.004 10.711  1.00 32.28  ? 192 ARG B NH2 1 
ATOM   5120  N N   . ARG B 1 193 ? -12.024 -25.993 4.169   1.00 34.03  ? 193 ARG B N   1 
ATOM   5121  C CA  . ARG B 1 193 ? -12.808 -24.790 4.007   1.00 35.90  ? 193 ARG B CA  1 
ATOM   5122  C C   . ARG B 1 193 ? -14.280 -25.141 3.827   1.00 36.34  ? 193 ARG B C   1 
ATOM   5123  O O   . ARG B 1 193 ? -15.115 -24.498 4.459   1.00 40.11  ? 193 ARG B O   1 
ATOM   5124  C CB  . ARG B 1 193 ? -12.304 -23.961 2.828   1.00 38.07  ? 193 ARG B CB  1 
ATOM   5125  C CG  . ARG B 1 193 ? -13.207 -22.790 2.519   1.00 34.67  ? 193 ARG B CG  1 
ATOM   5126  C CD  . ARG B 1 193 ? -12.602 -21.897 1.491   1.00 37.48  ? 193 ARG B CD  1 
ATOM   5127  N NE  . ARG B 1 193 ? -13.455 -20.723 1.362   1.00 38.30  ? 193 ARG B NE  1 
ATOM   5128  C CZ  . ARG B 1 193 ? -13.928 -20.280 0.211   1.00 37.24  ? 193 ARG B CZ  1 
ATOM   5129  N NH1 . ARG B 1 193 ? -13.689 -20.911 -0.931  1.00 41.47  ? 193 ARG B NH1 1 
ATOM   5130  N NH2 . ARG B 1 193 ? -14.607 -19.171 0.208   1.00 31.16  ? 193 ARG B NH2 1 
ATOM   5131  N N   . LYS B 1 194 ? -14.591 -26.124 2.966   1.00 36.88  ? 194 LYS B N   1 
ATOM   5132  C CA  . LYS B 1 194 ? -15.983 -26.484 2.691   1.00 37.97  ? 194 LYS B CA  1 
ATOM   5133  C C   . LYS B 1 194 ? -16.634 -27.244 3.850   1.00 39.41  ? 194 LYS B C   1 
ATOM   5134  O O   . LYS B 1 194 ? -17.793 -26.992 4.164   1.00 38.07  ? 194 LYS B O   1 
ATOM   5135  C CB  . LYS B 1 194 ? -16.121 -27.350 1.436   1.00 38.86  ? 194 LYS B CB  1 
ATOM   5136  C CG  . LYS B 1 194 ? -16.157 -26.581 0.129   1.00 37.84  ? 194 LYS B CG  1 
ATOM   5137  C CD  . LYS B 1 194 ? -16.267 -27.469 -1.101  1.00 38.17  ? 194 LYS B CD  1 
ATOM   5138  C CE  . LYS B 1 194 ? -17.687 -27.870 -1.435  1.00 38.93  ? 194 LYS B CE  1 
ATOM   5139  N NZ  . LYS B 1 194 ? -18.485 -26.694 -1.877  1.00 39.91  ? 194 LYS B NZ  1 
ATOM   5140  N N   . TYR B 1 195 ? -15.934 -28.182 4.510   1.00 40.48  ? 195 TYR B N   1 
ATOM   5141  C CA  . TYR B 1 195 ? -16.697 -29.118 5.331   1.00 42.96  ? 195 TYR B CA  1 
ATOM   5142  C C   . TYR B 1 195 ? -16.326 -29.076 6.798   1.00 43.88  ? 195 TYR B C   1 
ATOM   5143  O O   . TYR B 1 195 ? -17.129 -29.505 7.604   1.00 44.26  ? 195 TYR B O   1 
ATOM   5144  C CB  . TYR B 1 195 ? -16.614 -30.557 4.821   1.00 39.15  ? 195 TYR B CB  1 
ATOM   5145  C CG  . TYR B 1 195 ? -16.943 -30.709 3.352   1.00 33.72  ? 195 TYR B CG  1 
ATOM   5146  C CD1 . TYR B 1 195 ? -18.249 -30.624 2.873   1.00 34.26  ? 195 TYR B CD1 1 
ATOM   5147  C CD2 . TYR B 1 195 ? -15.931 -30.859 2.428   1.00 29.59  ? 195 TYR B CD2 1 
ATOM   5148  C CE1 . TYR B 1 195 ? -18.537 -30.803 1.521   1.00 29.04  ? 195 TYR B CE1 1 
ATOM   5149  C CE2 . TYR B 1 195 ? -16.190 -30.991 1.073   1.00 30.62  ? 195 TYR B CE2 1 
ATOM   5150  C CZ  . TYR B 1 195 ? -17.499 -30.997 0.624   1.00 32.49  ? 195 TYR B CZ  1 
ATOM   5151  O OH  . TYR B 1 195 ? -17.666 -31.164 -0.733  1.00 38.31  ? 195 TYR B OH  1 
ATOM   5152  N N   . LYS B 1 196 ? -15.164 -28.538 7.159   1.00 45.84  ? 196 LYS B N   1 
ATOM   5153  C CA  . LYS B 1 196 ? -14.729 -28.653 8.541   1.00 42.25  ? 196 LYS B CA  1 
ATOM   5154  C C   . LYS B 1 196 ? -14.479 -27.279 9.153   1.00 39.55  ? 196 LYS B C   1 
ATOM   5155  O O   . LYS B 1 196 ? -13.571 -27.117 9.924   1.00 38.76  ? 196 LYS B O   1 
ATOM   5156  C CB  . LYS B 1 196 ? -13.511 -29.561 8.603   1.00 45.80  ? 196 LYS B CB  1 
ATOM   5157  C CG  . LYS B 1 196 ? -13.757 -30.987 8.109   1.00 48.02  ? 196 LYS B CG  1 
ATOM   5158  C CD  . LYS B 1 196 ? -14.639 -31.829 9.013   1.00 42.67  ? 196 LYS B CD  1 
ATOM   5159  C CE  . LYS B 1 196 ? -14.848 -33.212 8.431   1.00 45.13  ? 196 LYS B CE  1 
ATOM   5160  N NZ  . LYS B 1 196 ? -15.792 -34.027 9.237   1.00 48.69  ? 196 LYS B NZ  1 
ATOM   5161  N N   . GLY B 1 197 ? -15.300 -26.299 8.797   1.00 38.86  ? 197 GLY B N   1 
ATOM   5162  C CA  . GLY B 1 197 ? -15.320 -25.033 9.495   1.00 40.58  ? 197 GLY B CA  1 
ATOM   5163  C C   . GLY B 1 197 ? -14.104 -24.160 9.214   1.00 37.96  ? 197 GLY B C   1 
ATOM   5164  O O   . GLY B 1 197 ? -13.807 -23.296 10.023  1.00 37.80  ? 197 GLY B O   1 
ATOM   5165  N N   . ASP B 1 198 ? -13.442 -24.380 8.070   1.00 36.71  ? 198 ASP B N   1 
ATOM   5166  C CA  . ASP B 1 198 ? -12.457 -23.458 7.540   1.00 34.34  ? 198 ASP B CA  1 
ATOM   5167  C C   . ASP B 1 198 ? -11.315 -23.286 8.537   1.00 39.77  ? 198 ASP B C   1 
ATOM   5168  O O   . ASP B 1 198 ? -10.755 -22.200 8.674   1.00 35.27  ? 198 ASP B O   1 
ATOM   5169  C CB  . ASP B 1 198 ? -13.122 -22.142 7.149   1.00 34.26  ? 198 ASP B CB  1 
ATOM   5170  C CG  . ASP B 1 198 ? -12.330 -21.215 6.254   1.00 40.36  ? 198 ASP B CG  1 
ATOM   5171  O OD1 . ASP B 1 198 ? -11.346 -21.683 5.637   1.00 39.98  ? 198 ASP B OD1 1 
ATOM   5172  O OD2 . ASP B 1 198 ? -12.659 -19.995 6.255   1.00 42.67  ? 198 ASP B OD2 1 
ATOM   5173  N N   . THR B 1 199 ? -10.955 -24.404 9.165   1.00 42.99  ? 199 THR B N   1 
ATOM   5174  C CA  . THR B 1 199 ? -9.765  -24.573 9.989   1.00 49.96  ? 199 THR B CA  1 
ATOM   5175  C C   . THR B 1 199 ? -8.713  -25.327 9.170   1.00 45.24  ? 199 THR B C   1 
ATOM   5176  O O   . THR B 1 199 ? -9.029  -26.322 8.535   1.00 41.48  ? 199 THR B O   1 
ATOM   5177  C CB  . THR B 1 199 ? -10.181 -25.310 11.277  1.00 56.23  ? 199 THR B CB  1 
ATOM   5178  O OG1 . THR B 1 199 ? -10.770 -24.327 12.133  1.00 61.22  ? 199 THR B OG1 1 
ATOM   5179  C CG2 . THR B 1 199 ? -9.046  -25.981 12.009  1.00 71.81  ? 199 THR B CG2 1 
ATOM   5180  N N   . HIS B 1 200 ? -7.455  -24.893 9.215   1.00 42.65  ? 200 HIS B N   1 
ATOM   5181  C CA  . HIS B 1 200 ? -6.464  -25.386 8.277   1.00 46.31  ? 200 HIS B CA  1 
ATOM   5182  C C   . HIS B 1 200 ? -5.281  -26.021 9.006   1.00 47.10  ? 200 HIS B C   1 
ATOM   5183  O O   . HIS B 1 200 ? -4.733  -25.427 9.910   1.00 42.78  ? 200 HIS B O   1 
ATOM   5184  C CB  . HIS B 1 200 ? -6.116  -24.268 7.305   1.00 42.60  ? 200 HIS B CB  1 
ATOM   5185  C CG  . HIS B 1 200 ? -7.306  -23.907 6.495   1.00 42.93  ? 200 HIS B CG  1 
ATOM   5186  N ND1 . HIS B 1 200 ? -7.700  -24.634 5.393   1.00 43.52  ? 200 HIS B ND1 1 
ATOM   5187  C CD2 . HIS B 1 200 ? -8.204  -22.942 6.646   1.00 46.53  ? 200 HIS B CD2 1 
ATOM   5188  C CE1 . HIS B 1 200 ? -8.791  -24.083 4.886   1.00 48.33  ? 200 HIS B CE1 1 
ATOM   5189  N NE2 . HIS B 1 200 ? -9.141  -23.081 5.653   1.00 47.12  ? 200 HIS B NE2 1 
ATOM   5190  N N   . ILE B 1 201 ? -4.941  -27.258 8.617   1.00 48.76  ? 201 ILE B N   1 
ATOM   5191  C CA  . ILE B 1 201 ? -3.884  -28.037 9.230   1.00 47.88  ? 201 ILE B CA  1 
ATOM   5192  C C   . ILE B 1 201 ? -2.681  -28.133 8.288   1.00 52.06  ? 201 ILE B C   1 
ATOM   5193  O O   . ILE B 1 201 ? -2.793  -28.547 7.119   1.00 43.22  ? 201 ILE B O   1 
ATOM   5194  C CB  . ILE B 1 201 ? -4.421  -29.427 9.594   1.00 46.89  ? 201 ILE B CB  1 
ATOM   5195  C CG1 . ILE B 1 201 ? -5.561  -29.351 10.602  1.00 40.75  ? 201 ILE B CG1 1 
ATOM   5196  C CG2 . ILE B 1 201 ? -3.288  -30.286 10.115  1.00 51.85  ? 201 ILE B CG2 1 
ATOM   5197  C CD1 . ILE B 1 201 ? -6.500  -30.538 10.516  1.00 45.68  ? 201 ILE B CD1 1 
ATOM   5198  N N   . ALA B 1 202 ? -1.507  -27.783 8.837   1.00 50.45  ? 202 ALA B N   1 
ATOM   5199  C CA  . ALA B 1 202 ? -0.275  -27.801 8.062   1.00 45.29  ? 202 ALA B CA  1 
ATOM   5200  C C   . ALA B 1 202 ? 0.178   -29.233 7.764   1.00 40.46  ? 202 ALA B C   1 
ATOM   5201  O O   . ALA B 1 202 ? -0.193  -30.182 8.470   1.00 45.69  ? 202 ALA B O   1 
ATOM   5202  C CB  . ALA B 1 202 ? 0.811   -27.030 8.776   1.00 48.83  ? 202 ALA B CB  1 
ATOM   5203  N N   . PRO B 1 203 ? 0.950   -29.422 6.665   1.00 39.24  ? 203 PRO B N   1 
ATOM   5204  C CA  . PRO B 1 203 ? 1.643   -30.686 6.385   1.00 46.65  ? 203 PRO B CA  1 
ATOM   5205  C C   . PRO B 1 203 ? 2.603   -31.078 7.514   1.00 52.70  ? 203 PRO B C   1 
ATOM   5206  O O   . PRO B 1 203 ? 3.348   -30.248 8.018   1.00 49.49  ? 203 PRO B O   1 
ATOM   5207  C CB  . PRO B 1 203 ? 2.464   -30.472 5.093   1.00 42.97  ? 203 PRO B CB  1 
ATOM   5208  C CG  . PRO B 1 203 ? 2.165   -29.046 4.637   1.00 44.56  ? 203 PRO B CG  1 
ATOM   5209  C CD  . PRO B 1 203 ? 1.174   -28.414 5.605   1.00 40.11  ? 203 PRO B CD  1 
ATOM   5210  N N   . ASP B 1 204 ? 2.478   -32.324 7.965   1.00 51.77  ? 204 ASP B N   1 
ATOM   5211  C CA  . ASP B 1 204 ? 3.430   -32.952 8.852   1.00 62.59  ? 204 ASP B CA  1 
ATOM   5212  C C   . ASP B 1 204 ? 4.673   -33.348 8.043   1.00 63.21  ? 204 ASP B C   1 
ATOM   5213  O O   . ASP B 1 204 ? 4.595   -34.176 7.140   1.00 57.71  ? 204 ASP B O   1 
ATOM   5214  C CB  . ASP B 1 204 ? 2.751   -34.138 9.546   1.00 62.04  ? 204 ASP B CB  1 
ATOM   5215  C CG  . ASP B 1 204 ? 3.642   -34.825 10.567  1.00 65.07  ? 204 ASP B CG  1 
ATOM   5216  O OD1 . ASP B 1 204 ? 4.883   -34.576 10.525  1.00 51.31  ? 204 ASP B OD1 1 
ATOM   5217  O OD2 . ASP B 1 204 ? 3.082   -35.585 11.404  1.00 65.41  ? 204 ASP B OD2 1 
ATOM   5218  N N   . PRO B 1 205 ? 5.874   -32.791 8.318   1.00 65.49  ? 205 PRO B N   1 
ATOM   5219  C CA  . PRO B 1 205 ? 7.056   -33.154 7.535   1.00 60.77  ? 205 PRO B CA  1 
ATOM   5220  C C   . PRO B 1 205 ? 7.588   -34.567 7.800   1.00 63.27  ? 205 PRO B C   1 
ATOM   5221  O O   . PRO B 1 205 ? 8.545   -34.981 7.137   1.00 63.79  ? 205 PRO B O   1 
ATOM   5222  C CB  . PRO B 1 205 ? 8.102   -32.095 7.915   1.00 60.91  ? 205 PRO B CB  1 
ATOM   5223  C CG  . PRO B 1 205 ? 7.665   -31.605 9.299   1.00 69.98  ? 205 PRO B CG  1 
ATOM   5224  C CD  . PRO B 1 205 ? 6.159   -31.783 9.358   1.00 65.72  ? 205 PRO B CD  1 
ATOM   5225  N N   . ASN B 1 206 ? 6.964   -35.312 8.732   1.00 53.79  ? 206 ASN B N   1 
ATOM   5226  C CA  . ASN B 1 206 ? 7.390   -36.673 9.032   1.00 59.59  ? 206 ASN B CA  1 
ATOM   5227  C C   . ASN B 1 206 ? 6.369   -37.698 8.563   1.00 53.32  ? 206 ASN B C   1 
ATOM   5228  O O   . ASN B 1 206 ? 6.343   -38.807 9.068   1.00 63.46  ? 206 ASN B O   1 
ATOM   5229  C CB  . ASN B 1 206 ? 7.652   -36.877 10.532  1.00 69.43  ? 206 ASN B CB  1 
ATOM   5230  C CG  . ASN B 1 206 ? 8.789   -36.009 11.033  1.00 75.47  ? 206 ASN B CG  1 
ATOM   5231  O OD1 . ASN B 1 206 ? 9.917   -36.081 10.539  1.00 70.64  ? 206 ASN B OD1 1 
ATOM   5232  N ND2 . ASN B 1 206 ? 8.484   -35.135 11.975  1.00 79.22  ? 206 ASN B ND2 1 
ATOM   5233  N N   . LEU B 1 207 ? 5.478   -37.304 7.655   1.00 61.12  ? 207 LEU B N   1 
ATOM   5234  C CA  . LEU B 1 207 ? 4.497   -38.209 7.068   1.00 57.33  ? 207 LEU B CA  1 
ATOM   5235  C C   . LEU B 1 207 ? 4.713   -38.228 5.556   1.00 48.76  ? 207 LEU B C   1 
ATOM   5236  O O   . LEU B 1 207 ? 5.016   -37.211 4.918   1.00 46.63  ? 207 LEU B O   1 
ATOM   5237  C CB  . LEU B 1 207 ? 3.077   -37.733 7.396   1.00 53.77  ? 207 LEU B CB  1 
ATOM   5238  C CG  . LEU B 1 207 ? 2.493   -38.151 8.739   1.00 52.29  ? 207 LEU B CG  1 
ATOM   5239  C CD1 . LEU B 1 207 ? 1.097   -37.576 8.901   1.00 48.91  ? 207 LEU B CD1 1 
ATOM   5240  C CD2 . LEU B 1 207 ? 2.439   -39.659 8.868   1.00 57.44  ? 207 LEU B CD2 1 
ATOM   5241  N N   . ASP B 1 208 ? 4.437   -39.415 5.037   1.00 45.77  ? 208 ASP B N   1 
ATOM   5242  C CA  . ASP B 1 208 ? 4.538   -39.632 3.588   1.00 49.22  ? 208 ASP B CA  1 
ATOM   5243  C C   . ASP B 1 208 ? 3.427   -38.877 2.879   1.00 50.54  ? 208 ASP B C   1 
ATOM   5244  O O   . ASP B 1 208 ? 2.567   -38.298 3.547   1.00 47.41  ? 208 ASP B O   1 
ATOM   5245  C CB  . ASP B 1 208 ? 4.355   -41.115 3.286   1.00 46.99  ? 208 ASP B CB  1 
ATOM   5246  C CG  . ASP B 1 208 ? 3.262   -41.754 4.120   1.00 46.22  ? 208 ASP B CG  1 
ATOM   5247  O OD1 . ASP B 1 208 ? 3.438   -41.823 5.343   1.00 48.13  ? 208 ASP B OD1 1 
ATOM   5248  O OD2 . ASP B 1 208 ? 2.248   -42.165 3.539   1.00 50.01  ? 208 ASP B OD2 1 
ATOM   5249  N N   . TRP B 1 209 ? 3.421   -38.977 1.565   1.00 47.57  ? 209 TRP B N   1 
ATOM   5250  C CA  . TRP B 1 209 ? 2.460   -38.254 0.736   1.00 43.67  ? 209 TRP B CA  1 
ATOM   5251  C C   . TRP B 1 209 ? 1.009   -38.557 1.087   1.00 42.16  ? 209 TRP B C   1 
ATOM   5252  O O   . TRP B 1 209 ? 0.247   -37.648 1.373   1.00 47.50  ? 209 TRP B O   1 
ATOM   5253  C CB  . TRP B 1 209 ? 2.764   -38.589 -0.712  1.00 46.55  ? 209 TRP B CB  1 
ATOM   5254  C CG  . TRP B 1 209 ? 2.097   -37.738 -1.734  1.00 44.25  ? 209 TRP B CG  1 
ATOM   5255  C CD1 . TRP B 1 209 ? 2.339   -36.433 -2.035  1.00 42.81  ? 209 TRP B CD1 1 
ATOM   5256  C CD2 . TRP B 1 209 ? 1.109   -38.190 -2.663  1.00 43.91  ? 209 TRP B CD2 1 
ATOM   5257  N NE1 . TRP B 1 209 ? 1.549   -36.038 -3.077  1.00 44.34  ? 209 TRP B NE1 1 
ATOM   5258  C CE2 . TRP B 1 209 ? 0.807   -37.103 -3.503  1.00 43.29  ? 209 TRP B CE2 1 
ATOM   5259  C CE3 . TRP B 1 209 ? 0.441   -39.398 -2.845  1.00 41.95  ? 209 TRP B CE3 1 
ATOM   5260  C CZ2 . TRP B 1 209 ? -0.117  -37.202 -4.539  1.00 43.61  ? 209 TRP B CZ2 1 
ATOM   5261  C CZ3 . TRP B 1 209 ? -0.494  -39.479 -3.848  1.00 42.81  ? 209 TRP B CZ3 1 
ATOM   5262  C CH2 . TRP B 1 209 ? -0.774  -38.396 -4.676  1.00 39.07  ? 209 TRP B CH2 1 
ATOM   5263  N N   . SER B 1 210 ? 0.638   -39.832 1.127   1.00 47.47  ? 210 SER B N   1 
ATOM   5264  C CA  . SER B 1 210 ? -0.745  -40.239 1.351   1.00 41.35  ? 210 SER B CA  1 
ATOM   5265  C C   . SER B 1 210 ? -1.208  -39.849 2.739   1.00 44.27  ? 210 SER B C   1 
ATOM   5266  O O   . SER B 1 210 ? -2.401  -39.601 2.970   1.00 47.51  ? 210 SER B O   1 
ATOM   5267  C CB  . SER B 1 210 ? -0.907  -41.735 1.203   1.00 46.09  ? 210 SER B CB  1 
ATOM   5268  O OG  . SER B 1 210 ? -0.434  -42.184 -0.065  1.00 50.80  ? 210 SER B OG  1 
ATOM   5269  N N   . ALA B 1 211 ? -0.278  -39.932 3.689   1.00 49.27  ? 211 ALA B N   1 
ATOM   5270  C CA  . ALA B 1 211 ? -0.649  -39.781 5.085   1.00 50.85  ? 211 ALA B CA  1 
ATOM   5271  C C   . ALA B 1 211 ? -0.887  -38.305 5.346   1.00 43.39  ? 211 ALA B C   1 
ATOM   5272  O O   . ALA B 1 211 ? -1.807  -37.939 6.039   1.00 39.68  ? 211 ALA B O   1 
ATOM   5273  C CB  . ALA B 1 211 ? 0.427   -40.343 5.986   1.00 50.43  ? 211 ALA B CB  1 
ATOM   5274  N N   . ASN B 1 212 ? -0.037  -37.466 4.755   1.00 44.86  ? 212 ASN B N   1 
ATOM   5275  C CA  . ASN B 1 212 ? -0.234  -36.036 4.845   1.00 46.73  ? 212 ASN B CA  1 
ATOM   5276  C C   . ASN B 1 212 ? -1.624  -35.627 4.366   1.00 42.42  ? 212 ASN B C   1 
ATOM   5277  O O   . ASN B 1 212 ? -2.145  -34.660 4.914   1.00 48.08  ? 212 ASN B O   1 
ATOM   5278  C CB  . ASN B 1 212 ? 0.873   -35.241 4.148   1.00 45.90  ? 212 ASN B CB  1 
ATOM   5279  C CG  . ASN B 1 212 ? 1.791   -34.599 5.162   1.00 44.65  ? 212 ASN B CG  1 
ATOM   5280  O OD1 . ASN B 1 212 ? 1.318   -34.038 6.141   1.00 45.14  ? 212 ASN B OD1 1 
ATOM   5281  N ND2 . ASN B 1 212 ? 3.095   -34.687 4.967   1.00 45.73  ? 212 ASN B ND2 1 
ATOM   5282  N N   . LEU B 1 213 ? -2.244  -36.343 3.405   1.00 45.33  ? 213 LEU B N   1 
ATOM   5283  C CA  . LEU B 1 213 ? -3.546  -35.891 2.919   1.00 46.87  ? 213 LEU B CA  1 
ATOM   5284  C C   . LEU B 1 213 ? -4.630  -36.163 3.958   1.00 40.09  ? 213 LEU B C   1 
ATOM   5285  O O   . LEU B 1 213 ? -5.488  -35.327 4.170   1.00 46.79  ? 213 LEU B O   1 
ATOM   5286  C CB  . LEU B 1 213 ? -3.943  -36.504 1.574   1.00 44.78  ? 213 LEU B CB  1 
ATOM   5287  C CG  . LEU B 1 213 ? -5.327  -36.086 1.060   1.00 46.91  ? 213 LEU B CG  1 
ATOM   5288  C CD1 . LEU B 1 213 ? -5.478  -34.565 1.005   1.00 50.62  ? 213 LEU B CD1 1 
ATOM   5289  C CD2 . LEU B 1 213 ? -5.599  -36.639 -0.329  1.00 45.86  ? 213 LEU B CD2 1 
ATOM   5290  N N   . ALA B 1 214 ? -4.616  -37.335 4.578   1.00 41.70  ? 214 ALA B N   1 
ATOM   5291  C CA  . ALA B 1 214 ? -5.571  -37.643 5.636   1.00 41.53  ? 214 ALA B CA  1 
ATOM   5292  C C   . ALA B 1 214 ? -5.381  -36.703 6.823   1.00 40.29  ? 214 ALA B C   1 
ATOM   5293  O O   . ALA B 1 214 ? -6.353  -36.291 7.424   1.00 40.04  ? 214 ALA B O   1 
ATOM   5294  C CB  . ALA B 1 214 ? -5.389  -39.051 6.115   1.00 47.15  ? 214 ALA B CB  1 
ATOM   5295  N N   . HIS B 1 215 ? -4.127  -36.407 7.150   1.00 36.96  ? 215 HIS B N   1 
ATOM   5296  C CA  . HIS B 1 215 ? -3.767  -35.602 8.301   1.00 42.63  ? 215 HIS B CA  1 
ATOM   5297  C C   . HIS B 1 215 ? -4.332  -34.202 8.112   1.00 43.64  ? 215 HIS B C   1 
ATOM   5298  O O   . HIS B 1 215 ? -5.027  -33.686 8.987   1.00 42.65  ? 215 HIS B O   1 
ATOM   5299  C CB  . HIS B 1 215 ? -2.236  -35.524 8.427   1.00 43.23  ? 215 HIS B CB  1 
ATOM   5300  C CG  . HIS B 1 215 ? -1.737  -34.596 9.486   1.00 45.40  ? 215 HIS B CG  1 
ATOM   5301  N ND1 . HIS B 1 215 ? -2.067  -34.719 10.815  1.00 52.54  ? 215 HIS B ND1 1 
ATOM   5302  C CD2 . HIS B 1 215 ? -0.938  -33.532 9.412   1.00 46.77  ? 215 HIS B CD2 1 
ATOM   5303  C CE1 . HIS B 1 215 ? -1.488  -33.755 11.508  1.00 46.35  ? 215 HIS B CE1 1 
ATOM   5304  N NE2 . HIS B 1 215 ? -0.799  -33.024 10.678  1.00 47.90  ? 215 HIS B NE2 1 
ATOM   5305  N N   . MET B 1 216 ? -4.027  -33.624 6.942   1.00 38.21  ? 216 MET B N   1 
ATOM   5306  C CA  . MET B 1 216 ? -4.426  -32.263 6.632   1.00 35.58  ? 216 MET B CA  1 
ATOM   5307  C C   . MET B 1 216 ? -5.947  -32.185 6.448   1.00 35.91  ? 216 MET B C   1 
ATOM   5308  O O   . MET B 1 216 ? -6.552  -31.143 6.706   1.00 37.56  ? 216 MET B O   1 
ATOM   5309  C CB  . MET B 1 216 ? -3.709  -31.763 5.381   1.00 32.49  ? 216 MET B CB  1 
ATOM   5310  C CG  . MET B 1 216 ? -2.251  -31.484 5.586   1.00 34.89  ? 216 MET B CG  1 
ATOM   5311  S SD  . MET B 1 216 ? -1.468  -30.723 4.113   1.00 41.38  ? 216 MET B SD  1 
ATOM   5312  C CE  . MET B 1 216 ? -1.658  -32.111 2.996   1.00 38.93  ? 216 MET B CE  1 
ATOM   5313  N N   . MET B 1 217 ? -6.583  -33.325 6.149   1.00 34.67  ? 217 MET B N   1 
ATOM   5314  C CA  . MET B 1 217 ? -8.032  -33.363 6.117   1.00 35.77  ? 217 MET B CA  1 
ATOM   5315  C C   . MET B 1 217 ? -8.603  -33.477 7.529   1.00 37.99  ? 217 MET B C   1 
ATOM   5316  O O   . MET B 1 217 ? -9.774  -33.190 7.741   1.00 34.69  ? 217 MET B O   1 
ATOM   5317  C CB  . MET B 1 217 ? -8.524  -34.517 5.262   1.00 33.90  ? 217 MET B CB  1 
ATOM   5318  C CG  . MET B 1 217 ? -8.509  -34.206 3.791   1.00 37.20  ? 217 MET B CG  1 
ATOM   5319  S SD  . MET B 1 217 ? -8.803  -35.689 2.816   1.00 37.52  ? 217 MET B SD  1 
ATOM   5320  C CE  . MET B 1 217 ? -10.521 -35.961 3.231   1.00 33.24  ? 217 MET B CE  1 
ATOM   5321  N N   . GLY B 1 218 ? -7.774  -33.882 8.508   1.00 39.03  ? 218 GLY B N   1 
ATOM   5322  C CA  . GLY B 1 218 ? -8.232  -33.936 9.882   1.00 37.53  ? 218 GLY B CA  1 
ATOM   5323  C C   . GLY B 1 218 ? -8.447  -35.358 10.387  1.00 45.45  ? 218 GLY B C   1 
ATOM   5324  O O   . GLY B 1 218 ? -9.076  -35.501 11.418  1.00 40.35  ? 218 GLY B O   1 
ATOM   5325  N N   . PHE B 1 219 ? -7.890  -36.371 9.682   1.00 49.92  ? 219 PHE B N   1 
ATOM   5326  C CA  . PHE B 1 219 ? -7.958  -37.781 10.064  1.00 50.19  ? 219 PHE B CA  1 
ATOM   5327  C C   . PHE B 1 219 ? -6.550  -38.281 10.377  1.00 54.02  ? 219 PHE B C   1 
ATOM   5328  O O   . PHE B 1 219 ? -5.797  -38.589 9.457   1.00 60.03  ? 219 PHE B O   1 
ATOM   5329  C CB  . PHE B 1 219 ? -8.586  -38.626 8.951   1.00 47.25  ? 219 PHE B CB  1 
ATOM   5330  C CG  . PHE B 1 219 ? -9.971  -38.176 8.590   1.00 50.48  ? 219 PHE B CG  1 
ATOM   5331  C CD1 . PHE B 1 219 ? -11.067 -38.637 9.299   1.00 49.05  ? 219 PHE B CD1 1 
ATOM   5332  C CD2 . PHE B 1 219 ? -10.165 -37.176 7.642   1.00 48.84  ? 219 PHE B CD2 1 
ATOM   5333  C CE1 . PHE B 1 219 ? -12.345 -38.166 9.027   1.00 52.11  ? 219 PHE B CE1 1 
ATOM   5334  C CE2 . PHE B 1 219 ? -11.442 -36.702 7.374   1.00 46.68  ? 219 PHE B CE2 1 
ATOM   5335  C CZ  . PHE B 1 219 ? -12.534 -37.209 8.050   1.00 53.62  ? 219 PHE B CZ  1 
ATOM   5336  N N   . ASP B 1 220 ? -6.202  -38.259 11.674  1.00 56.26  ? 220 ASP B N   1 
ATOM   5337  C CA  . ASP B 1 220 ? -4.995  -38.853 12.225  1.00 55.68  ? 220 ASP B CA  1 
ATOM   5338  C C   . ASP B 1 220 ? -5.391  -40.161 12.900  1.00 57.00  ? 220 ASP B C   1 
ATOM   5339  O O   . ASP B 1 220 ? -5.850  -40.169 14.037  1.00 64.88  ? 220 ASP B O   1 
ATOM   5340  C CB  . ASP B 1 220 ? -4.315  -37.902 13.206  1.00 54.16  ? 220 ASP B CB  1 
ATOM   5341  C CG  . ASP B 1 220 ? -3.744  -36.683 12.515  1.00 59.33  ? 220 ASP B CG  1 
ATOM   5342  O OD1 . ASP B 1 220 ? -3.091  -36.870 11.494  1.00 63.24  ? 220 ASP B OD1 1 
ATOM   5343  O OD2 . ASP B 1 220 ? -3.939  -35.560 13.011  1.00 61.38  ? 220 ASP B OD2 1 
ATOM   5344  N N   . ASP B 1 221 ? -5.250  -41.242 12.141  1.00 57.19  ? 221 ASP B N   1 
ATOM   5345  C CA  . ASP B 1 221 ? -5.497  -42.612 12.553  1.00 59.60  ? 221 ASP B CA  1 
ATOM   5346  C C   . ASP B 1 221 ? -4.653  -43.514 11.636  1.00 69.20  ? 221 ASP B C   1 
ATOM   5347  O O   . ASP B 1 221 ? -4.601  -43.277 10.427  1.00 68.64  ? 221 ASP B O   1 
ATOM   5348  C CB  . ASP B 1 221 ? -6.994  -42.909 12.486  1.00 59.29  ? 221 ASP B CB  1 
ATOM   5349  C CG  . ASP B 1 221 ? -7.325  -44.392 12.562  1.00 65.38  ? 221 ASP B CG  1 
ATOM   5350  O OD1 . ASP B 1 221 ? -6.378  -45.194 12.481  1.00 71.22  ? 221 ASP B OD1 1 
ATOM   5351  O OD2 . ASP B 1 221 ? -8.525  -44.741 12.718  1.00 62.18  ? 221 ASP B OD2 1 
ATOM   5352  N N   . PHE B 1 222 ? -3.974  -44.540 12.190  1.00 75.73  ? 222 PHE B N   1 
ATOM   5353  C CA  . PHE B 1 222 ? -3.021  -45.324 11.405  1.00 66.76  ? 222 PHE B CA  1 
ATOM   5354  C C   . PHE B 1 222 ? -3.765  -46.078 10.306  1.00 60.85  ? 222 PHE B C   1 
ATOM   5355  O O   . PHE B 1 222 ? -3.236  -46.223 9.211   1.00 53.22  ? 222 PHE B O   1 
ATOM   5356  C CB  . PHE B 1 222 ? -2.186  -46.317 12.232  1.00 73.90  ? 222 PHE B CB  1 
ATOM   5357  C CG  . PHE B 1 222 ? -0.998  -46.924 11.501  1.00 71.90  ? 222 PHE B CG  1 
ATOM   5358  C CD1 . PHE B 1 222 ? 0.102   -46.147 11.131  1.00 64.05  ? 222 PHE B CD1 1 
ATOM   5359  C CD2 . PHE B 1 222 ? -0.991  -48.272 11.145  1.00 75.84  ? 222 PHE B CD2 1 
ATOM   5360  C CE1 . PHE B 1 222 ? 1.187   -46.700 10.456  1.00 63.91  ? 222 PHE B CE1 1 
ATOM   5361  C CE2 . PHE B 1 222 ? 0.085   -48.822 10.453  1.00 73.24  ? 222 PHE B CE2 1 
ATOM   5362  C CZ  . PHE B 1 222 ? 1.174   -48.038 10.114  1.00 67.60  ? 222 PHE B CZ  1 
ATOM   5363  N N   . GLU B 1 223 ? -4.968  -46.568 10.617  1.00 58.14  ? 223 GLU B N   1 
ATOM   5364  C CA  . GLU B 1 223 ? -5.790  -47.268 9.646   1.00 54.19  ? 223 GLU B CA  1 
ATOM   5365  C C   . GLU B 1 223 ? -6.131  -46.335 8.478   1.00 60.24  ? 223 GLU B C   1 
ATOM   5366  O O   . GLU B 1 223 ? -6.044  -46.735 7.313   1.00 51.33  ? 223 GLU B O   1 
ATOM   5367  C CB  . GLU B 1 223 ? -7.029  -47.804 10.351  1.00 57.88  ? 223 GLU B CB  1 
ATOM   5368  C CG  . GLU B 1 223 ? -6.696  -48.883 11.375  1.00 73.46  ? 223 GLU B CG  1 
ATOM   5369  C CD  . GLU B 1 223 ? -7.848  -49.776 11.816  1.00 77.12  ? 223 GLU B CD  1 
ATOM   5370  O OE1 . GLU B 1 223 ? -7.597  -50.656 12.677  1.00 89.71  ? 223 GLU B OE1 1 
ATOM   5371  O OE2 . GLU B 1 223 ? -8.997  -49.608 11.297  1.00 72.93  ? 223 GLU B OE2 1 
ATOM   5372  N N   . VAL B 1 224 ? -6.475  -45.074 8.791   1.00 54.45  ? 224 VAL B N   1 
ATOM   5373  C CA  . VAL B 1 224 ? -6.796  -44.103 7.760   1.00 51.73  ? 224 VAL B CA  1 
ATOM   5374  C C   . VAL B 1 224 ? -5.553  -43.882 6.895   1.00 43.86  ? 224 VAL B C   1 
ATOM   5375  O O   . VAL B 1 224 ? -5.648  -43.874 5.659   1.00 40.82  ? 224 VAL B O   1 
ATOM   5376  C CB  . VAL B 1 224 ? -7.357  -42.790 8.345   1.00 57.58  ? 224 VAL B CB  1 
ATOM   5377  C CG1 . VAL B 1 224 ? -7.638  -41.761 7.253   1.00 62.94  ? 224 VAL B CG1 1 
ATOM   5378  C CG2 . VAL B 1 224 ? -8.633  -43.035 9.134   1.00 56.07  ? 224 VAL B CG2 1 
ATOM   5379  N N   . TYR B 1 225 ? -4.376  -43.782 7.529   1.00 39.27  ? 225 TYR B N   1 
ATOM   5380  C CA  . TYR B 1 225 ? -3.159  -43.547 6.776   1.00 46.42  ? 225 TYR B CA  1 
ATOM   5381  C C   . TYR B 1 225 ? -2.935  -44.685 5.791   1.00 51.76  ? 225 TYR B C   1 
ATOM   5382  O O   . TYR B 1 225 ? -2.514  -44.439 4.659   1.00 50.34  ? 225 TYR B O   1 
ATOM   5383  C CB  . TYR B 1 225 ? -1.926  -43.394 7.665   1.00 55.24  ? 225 TYR B CB  1 
ATOM   5384  C CG  . TYR B 1 225 ? -1.859  -42.147 8.517   1.00 59.27  ? 225 TYR B CG  1 
ATOM   5385  C CD1 . TYR B 1 225 ? -2.859  -41.185 8.503   1.00 55.88  ? 225 TYR B CD1 1 
ATOM   5386  C CD2 . TYR B 1 225 ? -0.780  -41.950 9.365   1.00 56.52  ? 225 TYR B CD2 1 
ATOM   5387  C CE1 . TYR B 1 225 ? -2.776  -40.054 9.293   1.00 59.94  ? 225 TYR B CE1 1 
ATOM   5388  C CE2 . TYR B 1 225 ? -0.684  -40.825 10.166  1.00 59.85  ? 225 TYR B CE2 1 
ATOM   5389  C CZ  . TYR B 1 225 ? -1.692  -39.883 10.133  1.00 60.18  ? 225 TYR B CZ  1 
ATOM   5390  O OH  . TYR B 1 225 ? -1.582  -38.769 10.902  1.00 62.06  ? 225 TYR B OH  1 
ATOM   5391  N N   . GLU B 1 226 ? -3.190  -45.916 6.255   1.00 50.35  ? 226 GLU B N   1 
ATOM   5392  C CA  . GLU B 1 226 ? -3.037  -47.110 5.441   1.00 50.88  ? 226 GLU B CA  1 
ATOM   5393  C C   . GLU B 1 226 ? -4.086  -47.089 4.335   1.00 52.52  ? 226 GLU B C   1 
ATOM   5394  O O   . GLU B 1 226 ? -3.755  -47.279 3.171   1.00 47.57  ? 226 GLU B O   1 
ATOM   5395  C CB  . GLU B 1 226 ? -3.170  -48.382 6.292   1.00 51.80  ? 226 GLU B CB  1 
ATOM   5396  C CG  . GLU B 1 226 ? -1.940  -48.645 7.135   1.00 55.38  ? 226 GLU B CG  1 
ATOM   5397  C CD  . GLU B 1 226 ? -0.800  -49.282 6.363   1.00 60.14  ? 226 GLU B CD  1 
ATOM   5398  O OE1 . GLU B 1 226 ? 0.156   -48.552 5.995   1.00 56.04  ? 226 GLU B OE1 1 
ATOM   5399  O OE2 . GLU B 1 226 ? -0.863  -50.519 6.149   1.00 70.02  ? 226 GLU B OE2 1 
ATOM   5400  N N   . LEU B 1 227 ? -5.357  -46.886 4.699   1.00 44.25  ? 227 LEU B N   1 
ATOM   5401  C CA  . LEU B 1 227 ? -6.382  -46.870 3.683   1.00 47.77  ? 227 LEU B CA  1 
ATOM   5402  C C   . LEU B 1 227 ? -5.970  -45.922 2.544   1.00 53.04  ? 227 LEU B C   1 
ATOM   5403  O O   . LEU B 1 227 ? -5.994  -46.306 1.377   1.00 46.07  ? 227 LEU B O   1 
ATOM   5404  C CB  . LEU B 1 227 ? -7.706  -46.437 4.303   1.00 44.67  ? 227 LEU B CB  1 
ATOM   5405  C CG  . LEU B 1 227 ? -8.726  -45.939 3.289   1.00 44.41  ? 227 LEU B CG  1 
ATOM   5406  C CD1 . LEU B 1 227 ? -8.993  -46.993 2.230   1.00 46.97  ? 227 LEU B CD1 1 
ATOM   5407  C CD2 . LEU B 1 227 ? -10.005 -45.532 3.985   1.00 44.31  ? 227 LEU B CD2 1 
ATOM   5408  N N   . PHE B 1 228 ? -5.603  -44.684 2.888   1.00 46.20  ? 228 PHE B N   1 
ATOM   5409  C CA  . PHE B 1 228 ? -5.220  -43.700 1.892   1.00 47.46  ? 228 PHE B CA  1 
ATOM   5410  C C   . PHE B 1 228 ? -3.978  -44.132 1.106   1.00 50.70  ? 228 PHE B C   1 
ATOM   5411  O O   . PHE B 1 228 ? -3.821  -43.735 -0.058  1.00 39.42  ? 228 PHE B O   1 
ATOM   5412  C CB  . PHE B 1 228 ? -4.947  -42.342 2.543   1.00 41.63  ? 228 PHE B CB  1 
ATOM   5413  C CG  . PHE B 1 228 ? -6.149  -41.461 2.787   1.00 43.16  ? 228 PHE B CG  1 
ATOM   5414  C CD1 . PHE B 1 228 ? -7.317  -41.966 3.330   1.00 45.28  ? 228 PHE B CD1 1 
ATOM   5415  C CD2 . PHE B 1 228 ? -6.105  -40.106 2.488   1.00 42.45  ? 228 PHE B CD2 1 
ATOM   5416  C CE1 . PHE B 1 228 ? -8.416  -41.152 3.546   1.00 43.43  ? 228 PHE B CE1 1 
ATOM   5417  C CE2 . PHE B 1 228 ? -7.213  -39.304 2.693   1.00 41.24  ? 228 PHE B CE2 1 
ATOM   5418  C CZ  . PHE B 1 228 ? -8.363  -39.824 3.233   1.00 39.00  ? 228 PHE B CZ  1 
ATOM   5419  N N   . ARG B 1 229 ? -3.058  -44.879 1.738   1.00 51.75  ? 229 ARG B N   1 
ATOM   5420  C CA  . ARG B 1 229 ? -1.871  -45.353 1.022   1.00 49.74  ? 229 ARG B CA  1 
ATOM   5421  C C   . ARG B 1 229 ? -2.308  -46.334 -0.066  1.00 48.46  ? 229 ARG B C   1 
ATOM   5422  O O   . ARG B 1 229 ? -1.784  -46.270 -1.188  1.00 44.11  ? 229 ARG B O   1 
ATOM   5423  C CB  . ARG B 1 229 ? -0.835  -46.032 1.922   1.00 51.34  ? 229 ARG B CB  1 
ATOM   5424  C CG  . ARG B 1 229 ? 0.118   -45.094 2.647   1.00 52.06  ? 229 ARG B CG  1 
ATOM   5425  C CD  . ARG B 1 229 ? 0.436   -45.594 4.039   1.00 49.97  ? 229 ARG B CD  1 
ATOM   5426  N NE  . ARG B 1 229 ? 1.284   -44.647 4.737   1.00 55.03  ? 229 ARG B NE  1 
ATOM   5427  C CZ  . ARG B 1 229 ? 1.358   -44.529 6.063   1.00 49.54  ? 229 ARG B CZ  1 
ATOM   5428  N NH1 . ARG B 1 229 ? 0.701   -45.350 6.863   1.00 49.46  ? 229 ARG B NH1 1 
ATOM   5429  N NH2 . ARG B 1 229 ? 2.107   -43.579 6.579   1.00 43.62  ? 229 ARG B NH2 1 
ATOM   5430  N N   . LEU B 1 230 ? -3.274  -47.196 0.289   1.00 42.38  ? 230 LEU B N   1 
ATOM   5431  C CA  . LEU B 1 230 ? -3.770  -48.229 -0.603  1.00 50.15  ? 230 LEU B CA  1 
ATOM   5432  C C   . LEU B 1 230 ? -4.586  -47.584 -1.720  1.00 49.39  ? 230 LEU B C   1 
ATOM   5433  O O   . LEU B 1 230 ? -4.352  -47.912 -2.885  1.00 46.39  ? 230 LEU B O   1 
ATOM   5434  C CB  . LEU B 1 230 ? -4.596  -49.284 0.154   1.00 49.18  ? 230 LEU B CB  1 
ATOM   5435  C CG  . LEU B 1 230 ? -5.385  -50.287 -0.711  1.00 55.68  ? 230 LEU B CG  1 
ATOM   5436  C CD1 . LEU B 1 230 ? -4.476  -51.079 -1.643  1.00 52.31  ? 230 LEU B CD1 1 
ATOM   5437  C CD2 . LEU B 1 230 ? -6.192  -51.251 0.136   1.00 55.62  ? 230 LEU B CD2 1 
ATOM   5438  N N   . TYR B 1 231 ? -5.533  -46.708 -1.335  1.00 49.92  ? 231 TYR B N   1 
ATOM   5439  C CA  . TYR B 1 231 ? -6.386  -45.940 -2.246  1.00 49.50  ? 231 TYR B CA  1 
ATOM   5440  C C   . TYR B 1 231 ? -5.565  -45.265 -3.359  1.00 46.90  ? 231 TYR B C   1 
ATOM   5441  O O   . TYR B 1 231 ? -5.769  -45.506 -4.550  1.00 41.44  ? 231 TYR B O   1 
ATOM   5442  C CB  . TYR B 1 231 ? -7.233  -44.935 -1.465  1.00 44.86  ? 231 TYR B CB  1 
ATOM   5443  C CG  . TYR B 1 231 ? -8.253  -44.195 -2.291  1.00 48.27  ? 231 TYR B CG  1 
ATOM   5444  C CD1 . TYR B 1 231 ? -7.847  -43.171 -3.136  1.00 52.43  ? 231 TYR B CD1 1 
ATOM   5445  C CD2 . TYR B 1 231 ? -9.596  -44.512 -2.268  1.00 50.13  ? 231 TYR B CD2 1 
ATOM   5446  C CE1 . TYR B 1 231 ? -8.736  -42.508 -3.958  1.00 43.97  ? 231 TYR B CE1 1 
ATOM   5447  C CE2 . TYR B 1 231 ? -10.510 -43.845 -3.079  1.00 51.12  ? 231 TYR B CE2 1 
ATOM   5448  C CZ  . TYR B 1 231 ? -10.074 -42.833 -3.924  1.00 50.78  ? 231 TYR B CZ  1 
ATOM   5449  O OH  . TYR B 1 231 ? -10.886 -42.099 -4.773  1.00 57.66  ? 231 TYR B OH  1 
ATOM   5450  N N   . MET B 1 232 ? -4.585  -44.467 -2.969  1.00 43.56  ? 232 MET B N   1 
ATOM   5451  C CA  . MET B 1 232 ? -3.775  -43.742 -3.919  1.00 46.16  ? 232 MET B CA  1 
ATOM   5452  C C   . MET B 1 232 ? -3.010  -44.710 -4.833  1.00 49.38  ? 232 MET B C   1 
ATOM   5453  O O   . MET B 1 232 ? -2.747  -44.396 -5.988  1.00 41.12  ? 232 MET B O   1 
ATOM   5454  C CB  . MET B 1 232 ? -2.807  -42.843 -3.148  1.00 49.67  ? 232 MET B CB  1 
ATOM   5455  C CG  . MET B 1 232 ? -3.518  -41.764 -2.307  1.00 53.76  ? 232 MET B CG  1 
ATOM   5456  S SD  . MET B 1 232 ? -4.493  -40.685 -3.336  1.00 51.10  ? 232 MET B SD  1 
ATOM   5457  C CE  . MET B 1 232 ? -5.769  -40.069 -2.237  1.00 49.89  ? 232 MET B CE  1 
ATOM   5458  N N   . PHE B 1 233 ? -2.625  -45.879 -4.316  1.00 52.45  ? 233 PHE B N   1 
ATOM   5459  C CA  . PHE B 1 233 ? -1.882  -46.886 -5.076  1.00 50.96  ? 233 PHE B CA  1 
ATOM   5460  C C   . PHE B 1 233 ? -2.782  -47.520 -6.141  1.00 43.64  ? 233 PHE B C   1 
ATOM   5461  O O   . PHE B 1 233 ? -2.426  -47.582 -7.314  1.00 47.63  ? 233 PHE B O   1 
ATOM   5462  C CB  . PHE B 1 233 ? -1.316  -47.959 -4.133  1.00 55.84  ? 233 PHE B CB  1 
ATOM   5463  C CG  . PHE B 1 233 ? -0.849  -49.226 -4.801  1.00 48.94  ? 233 PHE B CG  1 
ATOM   5464  C CD1 . PHE B 1 233 ? 0.375   -49.283 -5.455  1.00 49.90  ? 233 PHE B CD1 1 
ATOM   5465  C CD2 . PHE B 1 233 ? -1.645  -50.362 -4.787  1.00 48.31  ? 233 PHE B CD2 1 
ATOM   5466  C CE1 . PHE B 1 233 ? 0.793   -50.465 -6.063  1.00 57.98  ? 233 PHE B CE1 1 
ATOM   5467  C CE2 . PHE B 1 233 ? -1.236  -51.532 -5.417  1.00 53.85  ? 233 PHE B CE2 1 
ATOM   5468  C CZ  . PHE B 1 233 ? -0.014  -51.589 -6.050  1.00 50.33  ? 233 PHE B CZ  1 
ATOM   5469  N N   . LEU B 1 234 ? -3.972  -47.914 -5.714  1.00 37.45  ? 234 LEU B N   1 
ATOM   5470  C CA  . LEU B 1 234 ? -4.950  -48.587 -6.540  1.00 44.72  ? 234 LEU B CA  1 
ATOM   5471  C C   . LEU B 1 234 ? -5.414  -47.741 -7.720  1.00 50.87  ? 234 LEU B C   1 
ATOM   5472  O O   . LEU B 1 234 ? -5.610  -48.295 -8.802  1.00 55.69  ? 234 LEU B O   1 
ATOM   5473  C CB  . LEU B 1 234 ? -6.155  -48.966 -5.668  1.00 44.96  ? 234 LEU B CB  1 
ATOM   5474  C CG  . LEU B 1 234 ? -5.925  -50.090 -4.651  1.00 54.25  ? 234 LEU B CG  1 
ATOM   5475  C CD1 . LEU B 1 234 ? -7.256  -50.532 -4.035  1.00 56.40  ? 234 LEU B CD1 1 
ATOM   5476  C CD2 . LEU B 1 234 ? -5.188  -51.273 -5.263  1.00 54.90  ? 234 LEU B CD2 1 
ATOM   5477  N N   . HIS B 1 235 ? -5.672  -46.442 -7.489  1.00 45.82  ? 235 HIS B N   1 
ATOM   5478  C CA  . HIS B 1 235 ? -6.375  -45.613 -8.451  1.00 40.04  ? 235 HIS B CA  1 
ATOM   5479  C C   . HIS B 1 235 ? -5.381  -44.804 -9.266  1.00 40.26  ? 235 HIS B C   1 
ATOM   5480  O O   . HIS B 1 235 ? -5.793  -43.966 -10.054 1.00 43.99  ? 235 HIS B O   1 
ATOM   5481  C CB  . HIS B 1 235 ? -7.373  -44.671 -7.784  1.00 46.25  ? 235 HIS B CB  1 
ATOM   5482  C CG  . HIS B 1 235 ? -8.532  -45.305 -7.115  1.00 42.65  ? 235 HIS B CG  1 
ATOM   5483  N ND1 . HIS B 1 235 ? -8.476  -45.835 -5.841  1.00 53.21  ? 235 HIS B ND1 1 
ATOM   5484  C CD2 . HIS B 1 235 ? -9.813  -45.359 -7.497  1.00 45.91  ? 235 HIS B CD2 1 
ATOM   5485  C CE1 . HIS B 1 235 ? -9.709  -46.238 -5.497  1.00 54.03  ? 235 HIS B CE1 1 
ATOM   5486  N NE2 . HIS B 1 235 ? -10.543 -45.939 -6.491  1.00 41.86  ? 235 HIS B NE2 1 
ATOM   5487  N N   . SER B 1 236 ? -4.082  -45.078 -9.065  1.00 40.98  ? 236 SER B N   1 
ATOM   5488  C CA  . SER B 1 236 ? -2.999  -44.359 -9.696  1.00 39.49  ? 236 SER B CA  1 
ATOM   5489  C C   . SER B 1 236 ? -3.158  -44.274 -11.216 1.00 48.27  ? 236 SER B C   1 
ATOM   5490  O O   . SER B 1 236 ? -2.885  -43.221 -11.803 1.00 41.08  ? 236 SER B O   1 
ATOM   5491  C CB  . SER B 1 236 ? -1.723  -45.037 -9.370  1.00 42.30  ? 236 SER B CB  1 
ATOM   5492  O OG  . SER B 1 236 ? -1.762  -46.380 -9.827  1.00 51.33  ? 236 SER B OG  1 
ATOM   5493  N N   . ASP B 1 237 ? -3.487  -45.413 -11.857 1.00 44.99  ? 237 ASP B N   1 
ATOM   5494  C CA  . ASP B 1 237 ? -3.374  -45.513 -13.299 1.00 46.00  ? 237 ASP B CA  1 
ATOM   5495  C C   . ASP B 1 237 ? -4.281  -46.610 -13.821 1.00 47.26  ? 237 ASP B C   1 
ATOM   5496  O O   . ASP B 1 237 ? -4.448  -47.627 -13.152 1.00 45.09  ? 237 ASP B O   1 
ATOM   5497  C CB  . ASP B 1 237 ? -1.940  -45.815 -13.720 1.00 51.71  ? 237 ASP B CB  1 
ATOM   5498  C CG  . ASP B 1 237 ? -1.665  -45.347 -15.133 1.00 61.93  ? 237 ASP B CG  1 
ATOM   5499  O OD1 . ASP B 1 237 ? -2.228  -44.264 -15.494 1.00 69.81  ? 237 ASP B OD1 1 
ATOM   5500  O OD2 . ASP B 1 237 ? -0.878  -46.041 -15.859 1.00 60.61  ? 237 ASP B OD2 1 
ATOM   5501  N N   . HIS B 1 238 ? -4.834  -46.397 -15.023 1.00 44.19  ? 238 HIS B N   1 
ATOM   5502  C CA  . HIS B 1 238 ? -5.670  -47.387 -15.688 1.00 44.16  ? 238 HIS B CA  1 
ATOM   5503  C C   . HIS B 1 238 ? -5.693  -47.121 -17.191 1.00 37.76  ? 238 HIS B C   1 
ATOM   5504  O O   . HIS B 1 238 ? -6.717  -46.772 -17.768 1.00 39.22  ? 238 HIS B O   1 
ATOM   5505  C CB  . HIS B 1 238 ? -7.081  -47.333 -15.109 1.00 48.29  ? 238 HIS B CB  1 
ATOM   5506  C CG  . HIS B 1 238 ? -7.851  -48.563 -15.440 1.00 64.63  ? 238 HIS B CG  1 
ATOM   5507  N ND1 . HIS B 1 238 ? -8.850  -48.593 -16.385 1.00 69.89  ? 238 HIS B ND1 1 
ATOM   5508  C CD2 . HIS B 1 238 ? -7.743  -49.815 -14.970 1.00 62.09  ? 238 HIS B CD2 1 
ATOM   5509  C CE1 . HIS B 1 238 ? -9.340  -49.820 -16.461 1.00 67.12  ? 238 HIS B CE1 1 
ATOM   5510  N NE2 . HIS B 1 238 ? -8.687  -50.572 -15.604 1.00 67.08  ? 238 HIS B NE2 1 
ATOM   5511  N N   . GLU B 1 239 ? -4.539  -47.255 -17.817 1.00 39.04  ? 239 GLU B N   1 
ATOM   5512  C CA  . GLU B 1 239 ? -4.396  -47.027 -19.251 1.00 48.91  ? 239 GLU B CA  1 
ATOM   5513  C C   . GLU B 1 239 ? -4.595  -45.544 -19.609 1.00 46.29  ? 239 GLU B C   1 
ATOM   5514  O O   . GLU B 1 239 ? -4.745  -44.687 -18.729 1.00 42.07  ? 239 GLU B O   1 
ATOM   5515  C CB  . GLU B 1 239 ? -5.327  -47.952 -20.048 1.00 52.00  ? 239 GLU B CB  1 
ATOM   5516  C CG  . GLU B 1 239 ? -4.710  -49.330 -20.282 1.00 63.07  ? 239 GLU B CG  1 
ATOM   5517  C CD  . GLU B 1 239 ? -5.375  -50.212 -21.327 1.00 61.79  ? 239 GLU B CD  1 
ATOM   5518  O OE1 . GLU B 1 239 ? -4.854  -51.344 -21.551 1.00 64.34  ? 239 GLU B OE1 1 
ATOM   5519  O OE2 . GLU B 1 239 ? -6.405  -49.774 -21.908 1.00 63.82  ? 239 GLU B OE2 1 
ATOM   5520  N N   . GLY B 1 240 ? -4.585  -45.274 -20.927 1.00 40.28  ? 240 GLY B N   1 
ATOM   5521  C CA  . GLY B 1 240 ? -4.577  -43.933 -21.474 1.00 42.13  ? 240 GLY B CA  1 
ATOM   5522  C C   . GLY B 1 240 ? -5.895  -43.470 -22.082 1.00 40.54  ? 240 GLY B C   1 
ATOM   5523  O O   . GLY B 1 240 ? -6.032  -42.305 -22.433 1.00 51.93  ? 240 GLY B O   1 
ATOM   5524  N N   . GLY B 1 241 ? -6.865  -44.358 -22.165 1.00 41.60  ? 241 GLY B N   1 
ATOM   5525  C CA  . GLY B 1 241 ? -8.074  -44.136 -22.924 1.00 40.99  ? 241 GLY B CA  1 
ATOM   5526  C C   . GLY B 1 241 ? -9.211  -43.500 -22.136 1.00 37.38  ? 241 GLY B C   1 
ATOM   5527  O O   . GLY B 1 241 ? -10.054 -42.840 -22.729 1.00 39.94  ? 241 GLY B O   1 
ATOM   5528  N N   . ASN B 1 242 ? -9.282  -43.730 -20.827 1.00 39.85  ? 242 ASN B N   1 
ATOM   5529  C CA  . ASN B 1 242 ? -10.324 -43.091 -20.022 1.00 38.33  ? 242 ASN B CA  1 
ATOM   5530  C C   . ASN B 1 242 ? -10.228 -41.559 -20.191 1.00 36.06  ? 242 ASN B C   1 
ATOM   5531  O O   . ASN B 1 242 ? -9.188  -41.026 -20.546 1.00 40.48  ? 242 ASN B O   1 
ATOM   5532  C CB  . ASN B 1 242 ? -10.263 -43.534 -18.567 1.00 35.58  ? 242 ASN B CB  1 
ATOM   5533  C CG  . ASN B 1 242 ? -9.036  -42.994 -17.845 1.00 42.37  ? 242 ASN B CG  1 
ATOM   5534  O OD1 . ASN B 1 242 ? -8.874  -41.784 -17.615 1.00 41.07  ? 242 ASN B OD1 1 
ATOM   5535  N ND2 . ASN B 1 242 ? -8.125  -43.886 -17.529 1.00 40.17  ? 242 ASN B ND2 1 
ATOM   5536  N N   . VAL B 1 243 ? -11.344 -40.851 -19.998 1.00 41.34  ? 243 VAL B N   1 
ATOM   5537  C CA  . VAL B 1 243 ? -11.452 -39.431 -20.316 1.00 44.39  ? 243 VAL B CA  1 
ATOM   5538  C C   . VAL B 1 243 ? -10.335 -38.599 -19.678 1.00 41.31  ? 243 VAL B C   1 
ATOM   5539  O O   . VAL B 1 243 ? -9.756  -37.734 -20.352 1.00 38.94  ? 243 VAL B O   1 
ATOM   5540  C CB  . VAL B 1 243 ? -12.831 -38.913 -19.897 1.00 47.76  ? 243 VAL B CB  1 
ATOM   5541  C CG1 . VAL B 1 243 ? -12.888 -37.389 -19.887 1.00 49.44  ? 243 VAL B CG1 1 
ATOM   5542  C CG2 . VAL B 1 243 ? -13.911 -39.510 -20.804 1.00 45.90  ? 243 VAL B CG2 1 
ATOM   5543  N N   . SER B 1 244 ? -10.044 -38.843 -18.385 1.00 37.79  ? 244 SER B N   1 
ATOM   5544  C CA  . SER B 1 244 ? -9.137  -37.968 -17.668 1.00 43.57  ? 244 SER B CA  1 
ATOM   5545  C C   . SER B 1 244 ? -7.722  -38.152 -18.214 1.00 44.07  ? 244 SER B C   1 
ATOM   5546  O O   . SER B 1 244 ? -7.029  -37.161 -18.484 1.00 41.55  ? 244 SER B O   1 
ATOM   5547  C CB  . SER B 1 244 ? -9.225  -38.120 -16.152 1.00 44.38  ? 244 SER B CB  1 
ATOM   5548  O OG  . SER B 1 244 ? -9.495  -39.448 -15.766 1.00 46.30  ? 244 SER B OG  1 
ATOM   5549  N N   . ALA B 1 245 ? -7.333  -39.417 -18.432 1.00 39.86  ? 245 ALA B N   1 
ATOM   5550  C CA  . ALA B 1 245 ? -6.020  -39.755 -18.958 1.00 35.83  ? 245 ALA B CA  1 
ATOM   5551  C C   . ALA B 1 245 ? -5.817  -39.196 -20.359 1.00 37.05  ? 245 ALA B C   1 
ATOM   5552  O O   . ALA B 1 245 ? -4.742  -38.695 -20.687 1.00 36.87  ? 245 ALA B O   1 
ATOM   5553  C CB  . ALA B 1 245 ? -5.823  -41.239 -18.945 1.00 41.46  ? 245 ALA B CB  1 
ATOM   5554  N N   . HIS B 1 246 ? -6.826  -39.354 -21.198 1.00 33.52  ? 246 HIS B N   1 
ATOM   5555  C CA  . HIS B 1 246 ? -6.746  -38.940 -22.589 1.00 35.64  ? 246 HIS B CA  1 
ATOM   5556  C C   . HIS B 1 246 ? -6.685  -37.397 -22.649 1.00 35.08  ? 246 HIS B C   1 
ATOM   5557  O O   . HIS B 1 246 ? -5.814  -36.808 -23.308 1.00 42.15  ? 246 HIS B O   1 
ATOM   5558  C CB  . HIS B 1 246 ? -7.926  -39.613 -23.314 1.00 36.90  ? 246 HIS B CB  1 
ATOM   5559  C CG  . HIS B 1 246 ? -7.992  -39.369 -24.773 1.00 36.19  ? 246 HIS B CG  1 
ATOM   5560  N ND1 . HIS B 1 246 ? -9.175  -39.470 -25.473 1.00 35.14  ? 246 HIS B ND1 1 
ATOM   5561  C CD2 . HIS B 1 246 ? -7.056  -38.951 -25.628 1.00 34.85  ? 246 HIS B CD2 1 
ATOM   5562  C CE1 . HIS B 1 246 ? -8.933  -39.110 -26.730 1.00 42.70  ? 246 HIS B CE1 1 
ATOM   5563  N NE2 . HIS B 1 246 ? -7.647  -38.839 -26.852 1.00 38.93  ? 246 HIS B NE2 1 
ATOM   5564  N N   . THR B 1 247 ? -7.551  -36.726 -21.885 1.00 33.78  ? 247 THR B N   1 
ATOM   5565  C CA  . THR B 1 247 ? -7.500  -35.270 -21.775 1.00 34.53  ? 247 THR B CA  1 
ATOM   5566  C C   . THR B 1 247 ? -6.083  -34.819 -21.471 1.00 35.61  ? 247 THR B C   1 
ATOM   5567  O O   . THR B 1 247 ? -5.539  -33.931 -22.141 1.00 40.53  ? 247 THR B O   1 
ATOM   5568  C CB  . THR B 1 247 ? -8.493  -34.731 -20.745 1.00 36.85  ? 247 THR B CB  1 
ATOM   5569  O OG1 . THR B 1 247 ? -9.773  -35.142 -21.218 1.00 32.79  ? 247 THR B OG1 1 
ATOM   5570  C CG2 . THR B 1 247 ? -8.468  -33.220 -20.603 1.00 40.09  ? 247 THR B CG2 1 
ATOM   5571  N N   . ASN B 1 248 ? -5.460  -35.503 -20.513 1.00 37.03  ? 248 ASN B N   1 
ATOM   5572  C CA  . ASN B 1 248 ? -4.121  -35.149 -20.088 1.00 34.89  ? 248 ASN B CA  1 
ATOM   5573  C C   . ASN B 1 248 ? -3.132  -35.281 -21.249 1.00 36.99  ? 248 ASN B C   1 
ATOM   5574  O O   . ASN B 1 248 ? -2.319  -34.394 -21.489 1.00 41.10  ? 248 ASN B O   1 
ATOM   5575  C CB  . ASN B 1 248 ? -3.717  -36.003 -18.888 1.00 37.09  ? 248 ASN B CB  1 
ATOM   5576  C CG  . ASN B 1 248 ? -2.313  -35.703 -18.445 1.00 38.54  ? 248 ASN B CG  1 
ATOM   5577  O OD1 . ASN B 1 248 ? -1.465  -36.596 -18.418 1.00 44.55  ? 248 ASN B OD1 1 
ATOM   5578  N ND2 . ASN B 1 248 ? -2.069  -34.449 -18.110 1.00 36.50  ? 248 ASN B ND2 1 
ATOM   5579  N N   . LEU B 1 249 ? -3.177  -36.398 -21.968 1.00 35.87  ? 249 LEU B N   1 
ATOM   5580  C CA  . LEU B 1 249 ? -2.248  -36.630 -23.071 1.00 34.66  ? 249 LEU B CA  1 
ATOM   5581  C C   . LEU B 1 249 ? -2.535  -35.643 -24.190 1.00 34.77  ? 249 LEU B C   1 
ATOM   5582  O O   . LEU B 1 249 ? -1.626  -35.069 -24.765 1.00 35.37  ? 249 LEU B O   1 
ATOM   5583  C CB  . LEU B 1 249 ? -2.429  -38.071 -23.583 1.00 38.53  ? 249 LEU B CB  1 
ATOM   5584  C CG  . LEU B 1 249 ? -1.968  -39.193 -22.654 1.00 39.54  ? 249 LEU B CG  1 
ATOM   5585  C CD1 . LEU B 1 249 ? -2.477  -40.532 -23.147 1.00 46.64  ? 249 LEU B CD1 1 
ATOM   5586  C CD2 . LEU B 1 249 ? -0.451  -39.229 -22.554 1.00 47.30  ? 249 LEU B CD2 1 
ATOM   5587  N N   . LEU B 1 250 ? -3.834  -35.445 -24.474 1.00 37.67  ? 250 LEU B N   1 
ATOM   5588  C CA  . LEU B 1 250 ? -4.242  -34.570 -25.554 1.00 36.34  ? 250 LEU B CA  1 
ATOM   5589  C C   . LEU B 1 250 ? -3.679  -33.157 -25.343 1.00 37.37  ? 250 LEU B C   1 
ATOM   5590  O O   . LEU B 1 250 ? -3.075  -32.572 -26.237 1.00 38.93  ? 250 LEU B O   1 
ATOM   5591  C CB  . LEU B 1 250 ? -5.766  -34.643 -25.622 1.00 35.95  ? 250 LEU B CB  1 
ATOM   5592  C CG  . LEU B 1 250 ? -6.461  -33.674 -26.569 1.00 39.48  ? 250 LEU B CG  1 
ATOM   5593  C CD1 . LEU B 1 250 ? -5.913  -33.757 -27.977 1.00 42.37  ? 250 LEU B CD1 1 
ATOM   5594  C CD2 . LEU B 1 250 ? -7.939  -33.995 -26.585 1.00 42.22  ? 250 LEU B CD2 1 
ATOM   5595  N N   . VAL B 1 251 ? -3.807  -32.607 -24.134 1.00 36.28  ? 251 VAL B N   1 
ATOM   5596  C CA  . VAL B 1 251 ? -3.379  -31.238 -23.898 1.00 31.50  ? 251 VAL B CA  1 
ATOM   5597  C C   . VAL B 1 251 ? -1.861  -31.210 -23.827 1.00 32.58  ? 251 VAL B C   1 
ATOM   5598  O O   . VAL B 1 251 ? -1.249  -30.267 -24.324 1.00 34.98  ? 251 VAL B O   1 
ATOM   5599  C CB  . VAL B 1 251 ? -4.043  -30.709 -22.622 1.00 36.14  ? 251 VAL B CB  1 
ATOM   5600  C CG1 . VAL B 1 251 ? -3.468  -29.374 -22.182 1.00 32.76  ? 251 VAL B CG1 1 
ATOM   5601  C CG2 . VAL B 1 251 ? -5.568  -30.658 -22.806 1.00 37.83  ? 251 VAL B CG2 1 
ATOM   5602  N N   . ASN B 1 252 ? -1.267  -32.264 -23.265 1.00 34.80  ? 252 ASN B N   1 
ATOM   5603  C CA  . ASN B 1 252 ? 0.182   -32.460 -23.234 1.00 37.90  ? 252 ASN B CA  1 
ATOM   5604  C C   . ASN B 1 252 ? 0.796   -32.451 -24.646 1.00 40.91  ? 252 ASN B C   1 
ATOM   5605  O O   . ASN B 1 252 ? 1.848   -31.844 -24.877 1.00 40.15  ? 252 ASN B O   1 
ATOM   5606  C CB  . ASN B 1 252 ? 0.569   -33.754 -22.508 1.00 36.99  ? 252 ASN B CB  1 
ATOM   5607  C CG  . ASN B 1 252 ? 2.062   -33.957 -22.522 1.00 41.13  ? 252 ASN B CG  1 
ATOM   5608  O OD1 . ASN B 1 252 ? 2.598   -34.575 -23.442 1.00 46.08  ? 252 ASN B OD1 1 
ATOM   5609  N ND2 . ASN B 1 252 ? 2.741   -33.338 -21.571 1.00 38.81  ? 252 ASN B ND2 1 
ATOM   5610  N N   . SER B 1 253 ? 0.072   -33.009 -25.615 1.00 38.47  ? 253 SER B N   1 
ATOM   5611  C CA  . SER B 1 253 ? 0.600   -33.178 -26.958 1.00 38.44  ? 253 SER B CA  1 
ATOM   5612  C C   . SER B 1 253 ? 0.766   -31.841 -27.657 1.00 39.77  ? 253 SER B C   1 
ATOM   5613  O O   . SER B 1 253 ? 1.393   -31.793 -28.696 1.00 44.38  ? 253 SER B O   1 
ATOM   5614  C CB  . SER B 1 253 ? -0.296  -34.075 -27.772 1.00 39.20  ? 253 SER B CB  1 
ATOM   5615  O OG  . SER B 1 253 ? -1.384  -33.343 -28.325 1.00 34.66  ? 253 SER B OG  1 
ATOM   5616  N N   . ALA B 1 254 ? 0.189   -30.759 -27.127 1.00 42.33  ? 254 ALA B N   1 
ATOM   5617  C CA  . ALA B 1 254 ? 0.377   -29.434 -27.724 1.00 41.43  ? 254 ALA B CA  1 
ATOM   5618  C C   . ALA B 1 254 ? 1.521   -28.668 -27.045 1.00 39.16  ? 254 ALA B C   1 
ATOM   5619  O O   . ALA B 1 254 ? 1.773   -27.510 -27.372 1.00 35.66  ? 254 ALA B O   1 
ATOM   5620  C CB  . ALA B 1 254 ? -0.909  -28.667 -27.652 1.00 34.27  ? 254 ALA B CB  1 
ATOM   5621  N N   . TYR B 1 255 ? 2.199   -29.332 -26.105 1.00 43.42  ? 255 TYR B N   1 
ATOM   5622  C CA  . TYR B 1 255 ? 3.353   -28.755 -25.353 1.00 42.94  ? 255 TYR B CA  1 
ATOM   5623  C C   . TYR B 1 255 ? 2.841   -27.952 -24.155 1.00 45.19  ? 255 TYR B C   1 
ATOM   5624  O O   . TYR B 1 255 ? 3.633   -27.240 -23.542 1.00 42.41  ? 255 TYR B O   1 
ATOM   5625  C CB  . TYR B 1 255 ? 4.343   -27.998 -26.244 1.00 47.55  ? 255 TYR B CB  1 
ATOM   5626  C CG  . TYR B 1 255 ? 5.269   -28.838 -27.083 1.00 50.07  ? 255 TYR B CG  1 
ATOM   5627  C CD1 . TYR B 1 255 ? 5.231   -30.222 -27.050 1.00 48.11  ? 255 TYR B CD1 1 
ATOM   5628  C CD2 . TYR B 1 255 ? 6.192   -28.238 -27.921 1.00 58.83  ? 255 TYR B CD2 1 
ATOM   5629  C CE1 . TYR B 1 255 ? 6.084   -30.984 -27.829 1.00 42.91  ? 255 TYR B CE1 1 
ATOM   5630  C CE2 . TYR B 1 255 ? 7.052   -28.984 -28.707 1.00 53.04  ? 255 TYR B CE2 1 
ATOM   5631  C CZ  . TYR B 1 255 ? 6.997   -30.363 -28.661 1.00 44.09  ? 255 TYR B CZ  1 
ATOM   5632  O OH  . TYR B 1 255 ? 7.857   -31.092 -29.440 1.00 56.10  ? 255 TYR B OH  1 
ATOM   5633  N N   . SER B 1 256 ? 1.552   -28.060 -23.847 1.00 41.29  ? 256 SER B N   1 
ATOM   5634  C CA  . SER B 1 256 ? 1.050   -27.431 -22.640 1.00 37.58  ? 256 SER B CA  1 
ATOM   5635  C C   . SER B 1 256 ? 1.584   -28.183 -21.434 1.00 36.03  ? 256 SER B C   1 
ATOM   5636  O O   . SER B 1 256 ? 1.534   -29.396 -21.394 1.00 35.30  ? 256 SER B O   1 
ATOM   5637  C CB  . SER B 1 256 ? -0.454  -27.382 -22.616 1.00 37.88  ? 256 SER B CB  1 
ATOM   5638  O OG  . SER B 1 256 ? -0.932  -26.305 -23.392 1.00 40.18  ? 256 SER B OG  1 
ATOM   5639  N N   . ASP B 1 257 ? 1.983   -27.446 -20.396 1.00 38.97  ? 257 ASP B N   1 
ATOM   5640  C CA  . ASP B 1 257 ? 2.618   -28.036 -19.219 1.00 34.95  ? 257 ASP B CA  1 
ATOM   5641  C C   . ASP B 1 257 ? 1.626   -28.829 -18.368 1.00 32.54  ? 257 ASP B C   1 
ATOM   5642  O O   . ASP B 1 257 ? 0.426   -28.838 -18.598 1.00 33.72  ? 257 ASP B O   1 
ATOM   5643  C CB  . ASP B 1 257 ? 3.275   -26.932 -18.399 1.00 37.38  ? 257 ASP B CB  1 
ATOM   5644  C CG  . ASP B 1 257 ? 2.279   -25.912 -17.861 1.00 41.43  ? 257 ASP B CG  1 
ATOM   5645  O OD1 . ASP B 1 257 ? 1.503   -26.273 -16.976 1.00 39.84  ? 257 ASP B OD1 1 
ATOM   5646  O OD2 . ASP B 1 257 ? 2.284   -24.774 -18.357 1.00 41.98  ? 257 ASP B OD2 1 
ATOM   5647  N N   . ILE B 1 258 ? 2.146   -29.474 -17.326 1.00 32.36  ? 258 ILE B N   1 
ATOM   5648  C CA  . ILE B 1 258 ? 1.391   -30.408 -16.523 1.00 30.16  ? 258 ILE B CA  1 
ATOM   5649  C C   . ILE B 1 258 ? 0.266   -29.746 -15.742 1.00 33.84  ? 258 ILE B C   1 
ATOM   5650  O O   . ILE B 1 258 ? -0.672  -30.440 -15.386 1.00 34.83  ? 258 ILE B O   1 
ATOM   5651  C CB  . ILE B 1 258 ? 2.336   -31.188 -15.602 1.00 30.95  ? 258 ILE B CB  1 
ATOM   5652  C CG1 . ILE B 1 258 ? 1.710   -32.467 -15.048 1.00 32.05  ? 258 ILE B CG1 1 
ATOM   5653  C CG2 . ILE B 1 258 ? 2.852   -30.337 -14.476 1.00 37.60  ? 258 ILE B CG2 1 
ATOM   5654  C CD1 . ILE B 1 258 ? 1.264   -33.407 -16.085 1.00 33.84  ? 258 ILE B CD1 1 
ATOM   5655  N N   . TYR B 1 259 ? 0.372   -28.442 -15.441 1.00 35.29  ? 259 TYR B N   1 
ATOM   5656  C CA  . TYR B 1 259 ? -0.651  -27.755 -14.677 1.00 33.91  ? 259 TYR B CA  1 
ATOM   5657  C C   . TYR B 1 259 ? -1.870  -27.506 -15.571 1.00 35.21  ? 259 TYR B C   1 
ATOM   5658  O O   . TYR B 1 259 ? -3.024  -27.709 -15.163 1.00 35.15  ? 259 TYR B O   1 
ATOM   5659  C CB  . TYR B 1 259 ? -0.085  -26.466 -14.079 1.00 33.87  ? 259 TYR B CB  1 
ATOM   5660  C CG  . TYR B 1 259 ? 0.992   -26.638 -13.039 1.00 33.38  ? 259 TYR B CG  1 
ATOM   5661  C CD1 . TYR B 1 259 ? 0.701   -26.907 -11.709 1.00 35.54  ? 259 TYR B CD1 1 
ATOM   5662  C CD2 . TYR B 1 259 ? 2.320   -26.537 -13.403 1.00 40.52  ? 259 TYR B CD2 1 
ATOM   5663  C CE1 . TYR B 1 259 ? 1.703   -27.046 -10.756 1.00 35.16  ? 259 TYR B CE1 1 
ATOM   5664  C CE2 . TYR B 1 259 ? 3.338   -26.675 -12.471 1.00 37.92  ? 259 TYR B CE2 1 
ATOM   5665  C CZ  . TYR B 1 259 ? 3.026   -26.921 -11.153 1.00 34.00  ? 259 TYR B CZ  1 
ATOM   5666  O OH  . TYR B 1 259 ? 4.086   -27.019 -10.325 1.00 36.57  ? 259 TYR B OH  1 
ATOM   5667  N N   . ARG B 1 260 ? -1.600  -27.120 -16.825 1.00 28.97  ? 260 ARG B N   1 
ATOM   5668  C CA  . ARG B 1 260 ? -2.641  -27.042 -17.832 1.00 30.83  ? 260 ARG B CA  1 
ATOM   5669  C C   . ARG B 1 260 ? -3.245  -28.393 -18.220 1.00 31.09  ? 260 ARG B C   1 
ATOM   5670  O O   . ARG B 1 260 ? -4.466  -28.496 -18.277 1.00 36.33  ? 260 ARG B O   1 
ATOM   5671  C CB  . ARG B 1 260 ? -2.070  -26.333 -19.056 1.00 34.06  ? 260 ARG B CB  1 
ATOM   5672  C CG  . ARG B 1 260 ? -1.852  -24.867 -18.765 1.00 31.08  ? 260 ARG B CG  1 
ATOM   5673  C CD  . ARG B 1 260 ? -1.338  -24.155 -19.991 1.00 33.51  ? 260 ARG B CD  1 
ATOM   5674  N NE  . ARG B 1 260 ? -1.459  -22.710 -19.842 1.00 34.76  ? 260 ARG B NE  1 
ATOM   5675  C CZ  . ARG B 1 260 ? -0.567  -21.874 -20.332 1.00 38.02  ? 260 ARG B CZ  1 
ATOM   5676  N NH1 . ARG B 1 260 ? -0.746  -20.566 -20.281 1.00 37.32  ? 260 ARG B NH1 1 
ATOM   5677  N NH2 . ARG B 1 260 ? 0.477   -22.376 -20.955 1.00 39.41  ? 260 ARG B NH2 1 
ATOM   5678  N N   . SER B 1 261 ? -2.430  -29.433 -18.456 1.00 35.03  ? 261 SER B N   1 
ATOM   5679  C CA  . SER B 1 261 ? -2.941  -30.750 -18.894 1.00 35.86  ? 261 SER B CA  1 
ATOM   5680  C C   . SER B 1 261 ? -3.708  -31.505 -17.809 1.00 34.21  ? 261 SER B C   1 
ATOM   5681  O O   . SER B 1 261 ? -4.754  -32.104 -18.081 1.00 32.69  ? 261 SER B O   1 
ATOM   5682  C CB  . SER B 1 261 ? -1.858  -31.643 -19.473 1.00 34.01  ? 261 SER B CB  1 
ATOM   5683  O OG  . SER B 1 261 ? -1.023  -32.202 -18.474 1.00 34.25  ? 261 SER B OG  1 
ATOM   5684  N N   . PHE B 1 262 ? -3.202  -31.472 -16.571 1.00 35.08  ? 262 PHE B N   1 
ATOM   5685  C CA  . PHE B 1 262 ? -3.861  -32.205 -15.504 1.00 31.32  ? 262 PHE B CA  1 
ATOM   5686  C C   . PHE B 1 262 ? -5.117  -31.476 -15.010 1.00 35.21  ? 262 PHE B C   1 
ATOM   5687  O O   . PHE B 1 262 ? -6.092  -32.108 -14.640 1.00 37.68  ? 262 PHE B O   1 
ATOM   5688  C CB  . PHE B 1 262 ? -2.872  -32.473 -14.375 1.00 33.03  ? 262 PHE B CB  1 
ATOM   5689  C CG  . PHE B 1 262 ? -3.489  -33.347 -13.334 1.00 35.75  ? 262 PHE B CG  1 
ATOM   5690  C CD1 . PHE B 1 262 ? -3.753  -34.676 -13.615 1.00 40.26  ? 262 PHE B CD1 1 
ATOM   5691  C CD2 . PHE B 1 262 ? -3.924  -32.814 -12.133 1.00 34.73  ? 262 PHE B CD2 1 
ATOM   5692  C CE1 . PHE B 1 262 ? -4.378  -35.482 -12.667 1.00 39.78  ? 262 PHE B CE1 1 
ATOM   5693  C CE2 . PHE B 1 262 ? -4.548  -33.616 -11.191 1.00 39.68  ? 262 PHE B CE2 1 
ATOM   5694  C CZ  . PHE B 1 262 ? -4.763  -34.950 -11.453 1.00 39.22  ? 262 PHE B CZ  1 
ATOM   5695  N N   . SER B 1 263 ? -5.162  -30.144 -15.053 1.00 33.44  ? 263 SER B N   1 
ATOM   5696  C CA  . SER B 1 263 ? -6.349  -29.450 -14.590 1.00 30.43  ? 263 SER B CA  1 
ATOM   5697  C C   . SER B 1 263 ? -7.475  -29.640 -15.604 1.00 34.90  ? 263 SER B C   1 
ATOM   5698  O O   . SER B 1 263 ? -8.653  -29.805 -15.231 1.00 31.35  ? 263 SER B O   1 
ATOM   5699  C CB  . SER B 1 263 ? -6.060  -27.970 -14.317 1.00 34.26  ? 263 SER B CB  1 
ATOM   5700  O OG  . SER B 1 263 ? -5.643  -27.260 -15.483 1.00 34.23  ? 263 SER B OG  1 
ATOM   5701  N N   . ALA B 1 264 ? -7.091  -29.594 -16.886 1.00 32.86  ? 264 ALA B N   1 
ATOM   5702  C CA  . ALA B 1 264 ? -7.961  -30.025 -17.968 1.00 36.25  ? 264 ALA B CA  1 
ATOM   5703  C C   . ALA B 1 264 ? -8.473  -31.446 -17.718 1.00 34.76  ? 264 ALA B C   1 
ATOM   5704  O O   . ALA B 1 264 ? -9.689  -31.696 -17.824 1.00 36.58  ? 264 ALA B O   1 
ATOM   5705  C CB  . ALA B 1 264 ? -7.244  -29.922 -19.301 1.00 38.49  ? 264 ALA B CB  1 
ATOM   5706  N N   . ALA B 1 265 ? -7.579  -32.359 -17.304 1.00 36.33  ? 265 ALA B N   1 
ATOM   5707  C CA  . ALA B 1 265 ? -7.990  -33.744 -17.027 1.00 33.86  ? 265 ALA B CA  1 
ATOM   5708  C C   . ALA B 1 265 ? -9.051  -33.786 -15.934 1.00 37.13  ? 265 ALA B C   1 
ATOM   5709  O O   . ALA B 1 265 ? -10.031 -34.526 -16.042 1.00 32.82  ? 265 ALA B O   1 
ATOM   5710  C CB  . ALA B 1 265 ? -6.814  -34.606 -16.646 1.00 32.43  ? 265 ALA B CB  1 
ATOM   5711  N N   . MET B 1 266 ? -8.885  -32.937 -14.908 1.00 35.17  ? 266 MET B N   1 
ATOM   5712  C CA  . MET B 1 266 ? -9.818  -32.909 -13.796 1.00 35.77  ? 266 MET B CA  1 
ATOM   5713  C C   . MET B 1 266 ? -11.165 -32.321 -14.218 1.00 35.25  ? 266 MET B C   1 
ATOM   5714  O O   . MET B 1 266 ? -12.191 -32.710 -13.693 1.00 35.47  ? 266 MET B O   1 
ATOM   5715  C CB  . MET B 1 266 ? -9.225  -32.110 -12.628 1.00 37.81  ? 266 MET B CB  1 
ATOM   5716  C CG  . MET B 1 266 ? -8.003  -32.752 -12.043 1.00 36.57  ? 266 MET B CG  1 
ATOM   5717  S SD  . MET B 1 266 ? -8.350  -34.408 -11.321 1.00 36.90  ? 266 MET B SD  1 
ATOM   5718  C CE  . MET B 1 266 ? -7.863  -35.471 -12.684 1.00 37.65  ? 266 MET B CE  1 
ATOM   5719  N N   . ASN B 1 267 ? -11.213 -31.410 -15.191 1.00 37.96  ? 267 ASN B N   1 
ATOM   5720  C CA  . ASN B 1 267 ? -12.507 -30.970 -15.690 1.00 34.17  ? 267 ASN B CA  1 
ATOM   5721  C C   . ASN B 1 267 ? -13.246 -32.139 -16.367 1.00 38.55  ? 267 ASN B C   1 
ATOM   5722  O O   . ASN B 1 267 ? -14.486 -32.240 -16.353 1.00 35.94  ? 267 ASN B O   1 
ATOM   5723  C CB  . ASN B 1 267 ? -12.357 -29.821 -16.686 1.00 38.21  ? 267 ASN B CB  1 
ATOM   5724  C CG  . ASN B 1 267 ? -11.992 -28.506 -16.030 1.00 40.74  ? 267 ASN B CG  1 
ATOM   5725  O OD1 . ASN B 1 267 ? -11.949 -28.403 -14.807 1.00 41.39  ? 267 ASN B OD1 1 
ATOM   5726  N ND2 . ASN B 1 267 ? -11.766 -27.490 -16.848 1.00 41.46  ? 267 ASN B ND2 1 
ATOM   5727  N N   . GLY B 1 268 ? -12.474 -33.021 -16.995 1.00 34.62  ? 268 GLY B N   1 
ATOM   5728  C CA  . GLY B 1 268 ? -13.011 -34.269 -17.503 1.00 38.42  ? 268 GLY B CA  1 
ATOM   5729  C C   . GLY B 1 268 ? -13.447 -35.231 -16.394 1.00 39.06  ? 268 GLY B C   1 
ATOM   5730  O O   . GLY B 1 268 ? -14.551 -35.763 -16.435 1.00 41.62  ? 268 GLY B O   1 
ATOM   5731  N N   . LEU B 1 269 ? -12.585 -35.492 -15.404 1.00 36.06  ? 269 LEU B N   1 
ATOM   5732  C CA  . LEU B 1 269 ? -12.953 -36.412 -14.333 1.00 33.98  ? 269 LEU B CA  1 
ATOM   5733  C C   . LEU B 1 269 ? -14.204 -35.929 -13.592 1.00 35.26  ? 269 LEU B C   1 
ATOM   5734  O O   . LEU B 1 269 ? -14.922 -36.724 -13.008 1.00 35.23  ? 269 LEU B O   1 
ATOM   5735  C CB  . LEU B 1 269 ? -11.769 -36.552 -13.374 1.00 38.94  ? 269 LEU B CB  1 
ATOM   5736  C CG  . LEU B 1 269 ? -11.927 -37.601 -12.283 1.00 44.00  ? 269 LEU B CG  1 
ATOM   5737  C CD1 . LEU B 1 269 ? -12.018 -39.007 -12.887 1.00 44.88  ? 269 LEU B CD1 1 
ATOM   5738  C CD2 . LEU B 1 269 ? -10.771 -37.507 -11.301 1.00 40.76  ? 269 LEU B CD2 1 
ATOM   5739  N N   . ALA B 1 270 ? -14.455 -34.614 -13.592 1.00 32.82  ? 270 ALA B N   1 
ATOM   5740  C CA  . ALA B 1 270 ? -15.584 -34.021 -12.894 1.00 35.24  ? 270 ALA B CA  1 
ATOM   5741  C C   . ALA B 1 270 ? -16.927 -34.407 -13.519 1.00 39.45  ? 270 ALA B C   1 
ATOM   5742  O O   . ALA B 1 270 ? -17.981 -34.178 -12.905 1.00 38.77  ? 270 ALA B O   1 
ATOM   5743  C CB  . ALA B 1 270 ? -15.427 -32.514 -12.901 1.00 36.11  ? 270 ALA B CB  1 
ATOM   5744  N N   . GLY B 1 271 ? -16.879 -34.858 -14.784 1.00 40.69  ? 271 GLY B N   1 
ATOM   5745  C CA  . GLY B 1 271 ? -18.052 -35.322 -15.502 1.00 38.90  ? 271 GLY B CA  1 
ATOM   5746  C C   . GLY B 1 271 ? -18.792 -36.451 -14.784 1.00 38.81  ? 271 GLY B C   1 
ATOM   5747  O O   . GLY B 1 271 ? -18.182 -37.442 -14.378 1.00 41.54  ? 271 GLY B O   1 
ATOM   5748  N N   . PRO B 1 272 ? -20.138 -36.382 -14.668 1.00 35.77  ? 272 PRO B N   1 
ATOM   5749  C CA  . PRO B 1 272 ? -20.919 -37.469 -14.077 1.00 40.78  ? 272 PRO B CA  1 
ATOM   5750  C C   . PRO B 1 272 ? -20.732 -38.885 -14.605 1.00 45.31  ? 272 PRO B C   1 
ATOM   5751  O O   . PRO B 1 272 ? -20.973 -39.838 -13.886 1.00 48.72  ? 272 PRO B O   1 
ATOM   5752  C CB  . PRO B 1 272 ? -22.357 -37.076 -14.400 1.00 43.20  ? 272 PRO B CB  1 
ATOM   5753  C CG  . PRO B 1 272 ? -22.323 -35.559 -14.435 1.00 45.22  ? 272 PRO B CG  1 
ATOM   5754  C CD  . PRO B 1 272 ? -20.949 -35.209 -14.985 1.00 40.01  ? 272 PRO B CD  1 
ATOM   5755  N N   . LEU B 1 273 ? -20.344 -39.041 -15.870 1.00 47.81  ? 273 LEU B N   1 
ATOM   5756  C CA  . LEU B 1 273 ? -20.156 -40.380 -16.425 1.00 51.13  ? 273 LEU B CA  1 
ATOM   5757  C C   . LEU B 1 273 ? -18.749 -40.916 -16.150 1.00 50.95  ? 273 LEU B C   1 
ATOM   5758  O O   . LEU B 1 273 ? -18.461 -42.068 -16.461 1.00 49.24  ? 273 LEU B O   1 
ATOM   5759  C CB  . LEU B 1 273 ? -20.415 -40.326 -17.937 1.00 53.15  ? 273 LEU B CB  1 
ATOM   5760  C CG  . LEU B 1 273 ? -21.839 -39.942 -18.346 1.00 52.19  ? 273 LEU B CG  1 
ATOM   5761  C CD1 . LEU B 1 273 ? -21.936 -39.688 -19.838 1.00 53.01  ? 273 LEU B CD1 1 
ATOM   5762  C CD2 . LEU B 1 273 ? -22.827 -41.013 -17.938 1.00 52.45  ? 273 LEU B CD2 1 
ATOM   5763  N N   . HIS B 1 274 ? -17.850 -40.093 -15.590 1.00 50.80  ? 274 HIS B N   1 
ATOM   5764  C CA  . HIS B 1 274 ? -16.460 -40.496 -15.495 1.00 49.03  ? 274 HIS B CA  1 
ATOM   5765  C C   . HIS B 1 274 ? -16.058 -40.645 -14.037 1.00 50.72  ? 274 HIS B C   1 
ATOM   5766  O O   . HIS B 1 274 ? -15.291 -41.535 -13.711 1.00 51.14  ? 274 HIS B O   1 
ATOM   5767  C CB  . HIS B 1 274 ? -15.538 -39.515 -16.228 1.00 49.22  ? 274 HIS B CB  1 
ATOM   5768  C CG  . HIS B 1 274 ? -14.097 -39.914 -16.150 1.00 47.01  ? 274 HIS B CG  1 
ATOM   5769  N ND1 . HIS B 1 274 ? -13.714 -41.211 -15.887 1.00 41.60  ? 274 HIS B ND1 1 
ATOM   5770  C CD2 . HIS B 1 274 ? -12.957 -39.233 -16.342 1.00 47.48  ? 274 HIS B CD2 1 
ATOM   5771  C CE1 . HIS B 1 274 ? -12.389 -41.294 -15.898 1.00 41.76  ? 274 HIS B CE1 1 
ATOM   5772  N NE2 . HIS B 1 274 ? -11.905 -40.101 -16.177 1.00 45.26  ? 274 HIS B NE2 1 
ATOM   5773  N N   . GLY B 1 275 ? -16.545 -39.758 -13.171 1.00 55.75  ? 275 GLY B N   1 
ATOM   5774  C CA  . GLY B 1 275 ? -15.956 -39.616 -11.848 1.00 53.58  ? 275 GLY B CA  1 
ATOM   5775  C C   . GLY B 1 275 ? -16.899 -39.885 -10.680 1.00 47.54  ? 275 GLY B C   1 
ATOM   5776  O O   . GLY B 1 275 ? -16.467 -39.671 -9.560  1.00 46.62  ? 275 GLY B O   1 
ATOM   5777  N N   . LEU B 1 276 ? -18.127 -40.391 -10.931 1.00 49.56  ? 276 LEU B N   1 
ATOM   5778  C CA  . LEU B 1 276 ? -19.156 -40.511 -9.898  1.00 52.66  ? 276 LEU B CA  1 
ATOM   5779  C C   . LEU B 1 276 ? -19.463 -41.966 -9.508  1.00 48.02  ? 276 LEU B C   1 
ATOM   5780  O O   . LEU B 1 276 ? -20.226 -42.178 -8.572  1.00 45.20  ? 276 LEU B O   1 
ATOM   5781  C CB  . LEU B 1 276 ? -20.445 -39.834 -10.368 1.00 47.39  ? 276 LEU B CB  1 
ATOM   5782  C CG  . LEU B 1 276 ? -20.496 -38.302 -10.409 1.00 53.52  ? 276 LEU B CG  1 
ATOM   5783  C CD1 . LEU B 1 276 ? -21.926 -37.829 -10.686 1.00 51.64  ? 276 LEU B CD1 1 
ATOM   5784  C CD2 . LEU B 1 276 ? -19.984 -37.665 -9.146  1.00 51.35  ? 276 LEU B CD2 1 
ATOM   5785  N N   . ALA B 1 277 ? -18.884 -42.952 -10.200 1.00 39.20  ? 277 ALA B N   1 
ATOM   5786  C CA  . ALA B 1 277 ? -19.184 -44.360 -9.965  1.00 54.20  ? 277 ALA B CA  1 
ATOM   5787  C C   . ALA B 1 277 ? -19.053 -44.758 -8.485  1.00 56.79  ? 277 ALA B C   1 
ATOM   5788  O O   . ALA B 1 277 ? -19.979 -45.323 -7.900  1.00 56.60  ? 277 ALA B O   1 
ATOM   5789  C CB  . ALA B 1 277 ? -18.287 -45.218 -10.832 1.00 57.00  ? 277 ALA B CB  1 
ATOM   5790  N N   . ASN B 1 278 ? -17.913 -44.465 -7.862  1.00 59.75  ? 278 ASN B N   1 
ATOM   5791  C CA  . ASN B 1 278 ? -17.710 -44.719 -6.408  1.00 61.19  ? 278 ASN B CA  1 
ATOM   5792  C C   . ASN B 1 278 ? -18.946 -44.280 -5.625  1.00 53.85  ? 278 ASN B C   1 
ATOM   5793  O O   . ASN B 1 278 ? -19.466 -45.086 -4.847  1.00 42.27  ? 278 ASN B O   1 
ATOM   5794  C CB  . ASN B 1 278 ? -16.471 -43.941 -5.941  1.00 56.08  ? 278 ASN B CB  1 
ATOM   5795  C CG  . ASN B 1 278 ? -16.182 -43.911 -4.454  1.00 58.41  ? 278 ASN B CG  1 
ATOM   5796  O OD1 . ASN B 1 278 ? -17.074 -43.985 -3.617  1.00 81.92  ? 278 ASN B OD1 1 
ATOM   5797  N ND2 . ASN B 1 278 ? -14.916 -43.763 -4.110  1.00 54.67  ? 278 ASN B ND2 1 
ATOM   5798  N N   . GLN B 1 279 ? -19.372 -43.037 -5.815  1.00 46.10  ? 279 GLN B N   1 
ATOM   5799  C CA  . GLN B 1 279 ? -20.478 -42.470 -5.068  1.00 46.62  ? 279 GLN B CA  1 
ATOM   5800  C C   . GLN B 1 279 ? -21.801 -43.219 -5.292  1.00 51.18  ? 279 GLN B C   1 
ATOM   5801  O O   . GLN B 1 279 ? -22.613 -43.381 -4.379  1.00 49.69  ? 279 GLN B O   1 
ATOM   5802  C CB  . GLN B 1 279 ? -20.659 -41.014 -5.508  1.00 48.56  ? 279 GLN B CB  1 
ATOM   5803  C CG  . GLN B 1 279 ? -19.331 -40.284 -5.612  1.00 55.23  ? 279 GLN B CG  1 
ATOM   5804  C CD  . GLN B 1 279 ? -19.437 -38.795 -5.803  1.00 56.85  ? 279 GLN B CD  1 
ATOM   5805  O OE1 . GLN B 1 279 ? -20.487 -38.177 -5.607  1.00 59.50  ? 279 GLN B OE1 1 
ATOM   5806  N NE2 . GLN B 1 279 ? -18.308 -38.219 -6.173  1.00 57.13  ? 279 GLN B NE2 1 
ATOM   5807  N N   . GLU B 1 280 ? -22.080 -43.591 -6.532  1.00 48.86  ? 280 GLU B N   1 
ATOM   5808  C CA  . GLU B 1 280 ? -23.329 -44.258 -6.844  1.00 63.43  ? 280 GLU B CA  1 
ATOM   5809  C C   . GLU B 1 280 ? -23.356 -45.617 -6.158  1.00 54.38  ? 280 GLU B C   1 
ATOM   5810  O O   . GLU B 1 280 ? -24.405 -45.983 -5.644  1.00 53.39  ? 280 GLU B O   1 
ATOM   5811  C CB  . GLU B 1 280 ? -23.547 -44.461 -8.353  1.00 67.90  ? 280 GLU B CB  1 
ATOM   5812  C CG  . GLU B 1 280 ? -23.734 -43.177 -9.138  1.00 75.84  ? 280 GLU B CG  1 
ATOM   5813  C CD  . GLU B 1 280 ? -23.879 -43.399 -10.637 1.00 96.70  ? 280 GLU B CD  1 
ATOM   5814  O OE1 . GLU B 1 280 ? -23.646 -42.406 -11.410 1.00 77.47  ? 280 GLU B OE1 1 
ATOM   5815  O OE2 . GLU B 1 280 ? -24.241 -44.564 -11.030 1.00 91.00  ? 280 GLU B OE2 1 
ATOM   5816  N N   . VAL B 1 281 ? -22.235 -46.362 -6.181  1.00 55.10  ? 281 VAL B N   1 
ATOM   5817  C CA  . VAL B 1 281 ? -22.175 -47.649 -5.493  1.00 54.91  ? 281 VAL B CA  1 
ATOM   5818  C C   . VAL B 1 281 ? -22.509 -47.434 -4.019  1.00 54.48  ? 281 VAL B C   1 
ATOM   5819  O O   . VAL B 1 281 ? -23.277 -48.192 -3.437  1.00 52.27  ? 281 VAL B O   1 
ATOM   5820  C CB  . VAL B 1 281 ? -20.824 -48.387 -5.628  1.00 53.44  ? 281 VAL B CB  1 
ATOM   5821  C CG1 . VAL B 1 281 ? -20.641 -49.466 -4.561  1.00 46.54  ? 281 VAL B CG1 1 
ATOM   5822  C CG2 . VAL B 1 281 ? -20.648 -49.005 -7.002  1.00 53.29  ? 281 VAL B CG2 1 
ATOM   5823  N N   . LEU B 1 282 ? -21.916 -46.407 -3.412  1.00 52.11  ? 282 LEU B N   1 
ATOM   5824  C CA  . LEU B 1 282 ? -22.106 -46.195 -1.988  1.00 60.28  ? 282 LEU B CA  1 
ATOM   5825  C C   . LEU B 1 282 ? -23.565 -45.848 -1.684  1.00 54.19  ? 282 LEU B C   1 
ATOM   5826  O O   . LEU B 1 282 ? -24.125 -46.396 -0.742  1.00 57.74  ? 282 LEU B O   1 
ATOM   5827  C CB  . LEU B 1 282 ? -21.140 -45.127 -1.463  1.00 55.26  ? 282 LEU B CB  1 
ATOM   5828  C CG  . LEU B 1 282 ? -21.212 -44.878 0.042   1.00 52.83  ? 282 LEU B CG  1 
ATOM   5829  C CD1 . LEU B 1 282 ? -20.964 -46.170 0.831   1.00 52.68  ? 282 LEU B CD1 1 
ATOM   5830  C CD2 . LEU B 1 282 ? -20.225 -43.808 0.437   1.00 57.18  ? 282 LEU B CD2 1 
ATOM   5831  N N   . ARG B 1 283 ? -24.185 -44.989 -2.500  1.00 63.35  ? 283 ARG B N   1 
ATOM   5832  C CA  . ARG B 1 283 ? -25.559 -44.557 -2.261  1.00 65.10  ? 283 ARG B CA  1 
ATOM   5833  C C   . ARG B 1 283 ? -26.500 -45.759 -2.375  1.00 61.53  ? 283 ARG B C   1 
ATOM   5834  O O   . ARG B 1 283 ? -27.472 -45.852 -1.636  1.00 54.55  ? 283 ARG B O   1 
ATOM   5835  C CB  . ARG B 1 283 ? -25.955 -43.437 -3.231  1.00 60.95  ? 283 ARG B CB  1 
ATOM   5836  C CG  . ARG B 1 283 ? -25.463 -42.053 -2.820  1.00 69.18  ? 283 ARG B CG  1 
ATOM   5837  C CD  . ARG B 1 283 ? -25.955 -41.031 -3.829  1.00 74.12  ? 283 ARG B CD  1 
ATOM   5838  N NE  . ARG B 1 283 ? -25.357 -39.713 -3.724  1.00 71.95  ? 283 ARG B NE  1 
ATOM   5839  C CZ  . ARG B 1 283 ? -25.630 -38.841 -2.768  1.00 84.22  ? 283 ARG B CZ  1 
ATOM   5840  N NH1 . ARG B 1 283 ? -26.385 -39.201 -1.749  1.00 90.69  ? 283 ARG B NH1 1 
ATOM   5841  N NH2 . ARG B 1 283 ? -25.130 -37.619 -2.809  1.00 86.44  ? 283 ARG B NH2 1 
ATOM   5842  N N   . TRP B 1 284 ? -26.160 -46.679 -3.290  1.00 56.18  ? 284 TRP B N   1 
ATOM   5843  C CA  . TRP B 1 284 ? -26.905 -47.906 -3.520  1.00 56.34  ? 284 TRP B CA  1 
ATOM   5844  C C   . TRP B 1 284 ? -26.806 -48.827 -2.300  1.00 55.76  ? 284 TRP B C   1 
ATOM   5845  O O   . TRP B 1 284 ? -27.823 -49.381 -1.870  1.00 45.70  ? 284 TRP B O   1 
ATOM   5846  C CB  . TRP B 1 284 ? -26.414 -48.602 -4.799  1.00 49.05  ? 284 TRP B CB  1 
ATOM   5847  C CG  . TRP B 1 284 ? -27.209 -49.794 -5.238  1.00 54.12  ? 284 TRP B CG  1 
ATOM   5848  C CD1 . TRP B 1 284 ? -28.409 -49.768 -5.885  1.00 58.08  ? 284 TRP B CD1 1 
ATOM   5849  C CD2 . TRP B 1 284 ? -26.878 -51.191 -5.063  1.00 53.83  ? 284 TRP B CD2 1 
ATOM   5850  N NE1 . TRP B 1 284 ? -28.834 -51.041 -6.141  1.00 61.43  ? 284 TRP B NE1 1 
ATOM   5851  C CE2 . TRP B 1 284 ? -27.924 -51.938 -5.638  1.00 62.15  ? 284 TRP B CE2 1 
ATOM   5852  C CE3 . TRP B 1 284 ? -25.792 -51.891 -4.521  1.00 56.14  ? 284 TRP B CE3 1 
ATOM   5853  C CZ2 . TRP B 1 284 ? -27.915 -53.336 -5.674  1.00 63.72  ? 284 TRP B CZ2 1 
ATOM   5854  C CZ3 . TRP B 1 284 ? -25.794 -53.272 -4.538  1.00 58.12  ? 284 TRP B CZ3 1 
ATOM   5855  C CH2 . TRP B 1 284 ? -26.845 -53.986 -5.100  1.00 58.35  ? 284 TRP B CH2 1 
ATOM   5856  N N   . ILE B 1 285 ? -25.579 -49.018 -1.782  1.00 50.60  ? 285 ILE B N   1 
ATOM   5857  C CA  . ILE B 1 285 ? -25.365 -49.825 -0.582  1.00 50.53  ? 285 ILE B CA  1 
ATOM   5858  C C   . ILE B 1 285 ? -26.217 -49.231 0.543   1.00 52.42  ? 285 ILE B C   1 
ATOM   5859  O O   . ILE B 1 285 ? -26.887 -49.973 1.260   1.00 50.85  ? 285 ILE B O   1 
ATOM   5860  C CB  . ILE B 1 285 ? -23.862 -49.927 -0.190  1.00 46.87  ? 285 ILE B CB  1 
ATOM   5861  C CG1 . ILE B 1 285 ? -23.016 -50.688 -1.211  1.00 40.23  ? 285 ILE B CG1 1 
ATOM   5862  C CG2 . ILE B 1 285 ? -23.674 -50.517 1.215   1.00 46.54  ? 285 ILE B CG2 1 
ATOM   5863  C CD1 . ILE B 1 285 ? -23.342 -52.165 -1.290  1.00 48.30  ? 285 ILE B CD1 1 
ATOM   5864  N N   . GLN B 1 286 ? -26.194 -47.895 0.687   1.00 51.97  ? 286 GLN B N   1 
ATOM   5865  C CA  . GLN B 1 286 ? -26.906 -47.233 1.775   1.00 58.75  ? 286 GLN B CA  1 
ATOM   5866  C C   . GLN B 1 286 ? -28.421 -47.382 1.574   1.00 60.73  ? 286 GLN B C   1 
ATOM   5867  O O   . GLN B 1 286 ? -29.152 -47.397 2.556   1.00 55.92  ? 286 GLN B O   1 
ATOM   5868  C CB  . GLN B 1 286 ? -26.495 -45.758 1.926   1.00 54.79  ? 286 GLN B CB  1 
ATOM   5869  C CG  . GLN B 1 286 ? -25.051 -45.579 2.390   1.00 63.43  ? 286 GLN B CG  1 
ATOM   5870  C CD  . GLN B 1 286 ? -24.502 -44.165 2.349   1.00 62.23  ? 286 GLN B CD  1 
ATOM   5871  O OE1 . GLN B 1 286 ? -23.940 -43.662 3.332   1.00 62.78  ? 286 GLN B OE1 1 
ATOM   5872  N NE2 . GLN B 1 286 ? -24.635 -43.522 1.198   1.00 52.70  ? 286 GLN B NE2 1 
ATOM   5873  N N   . MET B 1 287 ? -28.891 -47.453 0.316   1.00 58.57  ? 287 MET B N   1 
ATOM   5874  C CA  . MET B 1 287 ? -30.314 -47.608 0.019   1.00 59.98  ? 287 MET B CA  1 
ATOM   5875  C C   . MET B 1 287 ? -30.774 -49.045 0.356   1.00 64.26  ? 287 MET B C   1 
ATOM   5876  O O   . MET B 1 287 ? -31.936 -49.236 0.744   1.00 57.51  ? 287 MET B O   1 
ATOM   5877  C CB  . MET B 1 287 ? -30.600 -47.250 -1.452  1.00 56.13  ? 287 MET B CB  1 
ATOM   5878  C CG  . MET B 1 287 ? -31.989 -47.646 -1.981  1.00 63.50  ? 287 MET B CG  1 
ATOM   5879  S SD  . MET B 1 287 ? -32.165 -49.432 -2.416  1.00 61.37  ? 287 MET B SD  1 
ATOM   5880  C CE  . MET B 1 287 ? -30.973 -49.603 -3.748  1.00 66.87  ? 287 MET B CE  1 
ATOM   5881  N N   . LEU B 1 288 ? -29.853 -50.036 0.279   1.00 54.28  ? 288 LEU B N   1 
ATOM   5882  C CA  . LEU B 1 288 ? -30.137 -51.426 0.642   1.00 57.85  ? 288 LEU B CA  1 
ATOM   5883  C C   . LEU B 1 288 ? -30.298 -51.574 2.159   1.00 62.50  ? 288 LEU B C   1 
ATOM   5884  O O   . LEU B 1 288 ? -31.225 -52.238 2.628   1.00 56.52  ? 288 LEU B O   1 
ATOM   5885  C CB  . LEU B 1 288 ? -29.006 -52.345 0.156   1.00 57.78  ? 288 LEU B CB  1 
ATOM   5886  C CG  . LEU B 1 288 ? -28.985 -52.679 -1.335  1.00 60.44  ? 288 LEU B CG  1 
ATOM   5887  C CD1 . LEU B 1 288 ? -27.826 -53.633 -1.663  1.00 57.73  ? 288 LEU B CD1 1 
ATOM   5888  C CD2 . LEU B 1 288 ? -30.327 -53.269 -1.777  1.00 62.09  ? 288 LEU B CD2 1 
ATOM   5889  N N   . TYR B 1 289 ? -29.384 -50.953 2.918   1.00 61.42  ? 289 TYR B N   1 
ATOM   5890  C CA  . TYR B 1 289 ? -29.415 -50.974 4.377   1.00 70.07  ? 289 TYR B CA  1 
ATOM   5891  C C   . TYR B 1 289 ? -30.748 -50.415 4.891   1.00 67.32  ? 289 TYR B C   1 
ATOM   5892  O O   . TYR B 1 289 ? -31.401 -51.048 5.710   1.00 69.88  ? 289 TYR B O   1 
ATOM   5893  C CB  . TYR B 1 289 ? -28.171 -50.246 4.901   1.00 68.98  ? 289 TYR B CB  1 
ATOM   5894  C CG  . TYR B 1 289 ? -28.016 -50.119 6.395   1.00 78.63  ? 289 TYR B CG  1 
ATOM   5895  C CD1 . TYR B 1 289 ? -28.752 -49.189 7.118   1.00 87.94  ? 289 TYR B CD1 1 
ATOM   5896  C CD2 . TYR B 1 289 ? -27.096 -50.895 7.083   1.00 78.03  ? 289 TYR B CD2 1 
ATOM   5897  C CE1 . TYR B 1 289 ? -28.588 -49.042 8.485   1.00 88.39  ? 289 TYR B CE1 1 
ATOM   5898  C CE2 . TYR B 1 289 ? -26.922 -50.762 8.450   1.00 79.64  ? 289 TYR B CE2 1 
ATOM   5899  C CZ  . TYR B 1 289 ? -27.668 -49.832 9.152   1.00 86.09  ? 289 TYR B CZ  1 
ATOM   5900  O OH  . TYR B 1 289 ? -27.489 -49.691 10.505  1.00 78.04  ? 289 TYR B OH  1 
ATOM   5901  N N   . LYS B 1 290 ? -31.148 -49.242 4.386   1.00 68.68  ? 290 LYS B N   1 
ATOM   5902  C CA  . LYS B 1 290 ? -32.332 -48.525 4.838   1.00 74.86  ? 290 LYS B CA  1 
ATOM   5903  C C   . LYS B 1 290 ? -33.581 -49.285 4.402   1.00 72.25  ? 290 LYS B C   1 
ATOM   5904  O O   . LYS B 1 290 ? -34.559 -49.343 5.140   1.00 82.89  ? 290 LYS B O   1 
ATOM   5905  C CB  . LYS B 1 290 ? -32.331 -47.094 4.281   1.00 78.45  ? 290 LYS B CB  1 
ATOM   5906  C CG  . LYS B 1 290 ? -33.460 -46.196 4.759   1.00 85.36  ? 290 LYS B CG  1 
ATOM   5907  C CD  . LYS B 1 290 ? -33.609 -44.906 3.962   1.00 92.61  ? 290 LYS B CD  1 
ATOM   5908  C CE  . LYS B 1 290 ? -34.838 -44.114 4.375   1.00 95.44  ? 290 LYS B CE  1 
ATOM   5909  N NZ  . LYS B 1 290 ? -35.072 -42.931 3.511   1.00 93.19  ? 290 LYS B NZ  1 
ATOM   5910  N N   . LYS B 1 291 ? -33.531 -49.883 3.210   1.00 65.70  ? 291 LYS B N   1 
ATOM   5911  C CA  . LYS B 1 291 ? -34.637 -50.687 2.718   1.00 72.39  ? 291 LYS B CA  1 
ATOM   5912  C C   . LYS B 1 291 ? -34.890 -51.890 3.633   1.00 68.41  ? 291 LYS B C   1 
ATOM   5913  O O   . LYS B 1 291 ? -36.037 -52.239 3.898   1.00 60.34  ? 291 LYS B O   1 
ATOM   5914  C CB  . LYS B 1 291 ? -34.364 -51.140 1.280   1.00 72.96  ? 291 LYS B CB  1 
ATOM   5915  C CG  . LYS B 1 291 ? -35.467 -51.957 0.621   1.00 74.11  ? 291 LYS B CG  1 
ATOM   5916  C CD  . LYS B 1 291 ? -35.528 -51.770 -0.890  1.00 77.81  ? 291 LYS B CD  1 
ATOM   5917  C CE  . LYS B 1 291 ? -36.361 -52.807 -1.620  1.00 79.74  ? 291 LYS B CE  1 
ATOM   5918  N NZ  . LYS B 1 291 ? -37.816 -52.647 -1.381  1.00 75.23  ? 291 LYS B NZ  1 
ATOM   5919  N N   . PHE B 1 292 ? -33.829 -52.541 4.106   1.00 68.33  ? 292 PHE B N   1 
ATOM   5920  C CA  . PHE B 1 292 ? -33.985 -53.811 4.802   1.00 74.20  ? 292 PHE B CA  1 
ATOM   5921  C C   . PHE B 1 292 ? -33.720 -53.645 6.302   1.00 69.12  ? 292 PHE B C   1 
ATOM   5922  O O   . PHE B 1 292 ? -33.447 -54.625 6.987   1.00 73.81  ? 292 PHE B O   1 
ATOM   5923  C CB  . PHE B 1 292 ? -33.129 -54.890 4.117   1.00 77.22  ? 292 PHE B CB  1 
ATOM   5924  C CG  . PHE B 1 292 ? -33.609 -55.319 2.745   1.00 75.04  ? 292 PHE B CG  1 
ATOM   5925  C CD1 . PHE B 1 292 ? -34.840 -55.948 2.578   1.00 71.61  ? 292 PHE B CD1 1 
ATOM   5926  C CD2 . PHE B 1 292 ? -32.834 -55.093 1.613   1.00 76.09  ? 292 PHE B CD2 1 
ATOM   5927  C CE1 . PHE B 1 292 ? -35.288 -56.336 1.324   1.00 70.57  ? 292 PHE B CE1 1 
ATOM   5928  C CE2 . PHE B 1 292 ? -33.277 -55.492 0.356   1.00 83.84  ? 292 PHE B CE2 1 
ATOM   5929  C CZ  . PHE B 1 292 ? -34.501 -56.114 0.211   1.00 80.71  ? 292 PHE B CZ  1 
ATOM   5930  N N   . GLY B 1 293 ? -33.840 -52.409 6.814   1.00 66.53  ? 293 GLY B N   1 
ATOM   5931  C CA  . GLY B 1 293 ? -33.674 -52.114 8.232   1.00 70.87  ? 293 GLY B CA  1 
ATOM   5932  C C   . GLY B 1 293 ? -32.361 -52.638 8.820   1.00 70.42  ? 293 GLY B C   1 
ATOM   5933  O O   . GLY B 1 293 ? -32.239 -52.832 10.031  1.00 71.64  ? 293 GLY B O   1 
ATOM   5934  N N   . GLY B 1 294 ? -31.357 -52.829 7.962   1.00 69.00  ? 294 GLY B N   1 
ATOM   5935  C CA  . GLY B 1 294 ? -30.130 -53.503 8.357   1.00 68.18  ? 294 GLY B CA  1 
ATOM   5936  C C   . GLY B 1 294 ? -29.541 -54.292 7.191   1.00 60.60  ? 294 GLY B C   1 
ATOM   5937  O O   . GLY B 1 294 ? -29.961 -54.128 6.042   1.00 61.50  ? 294 GLY B O   1 
ATOM   5938  N N   . VAL B 1 295 ? -28.552 -55.131 7.501   1.00 56.50  ? 295 VAL B N   1 
ATOM   5939  C CA  . VAL B 1 295 ? -27.957 -55.964 6.480   1.00 64.23  ? 295 VAL B CA  1 
ATOM   5940  C C   . VAL B 1 295 ? -29.046 -56.928 6.035   1.00 66.61  ? 295 VAL B C   1 
ATOM   5941  O O   . VAL B 1 295 ? -29.709 -57.528 6.880   1.00 68.59  ? 295 VAL B O   1 
ATOM   5942  C CB  . VAL B 1 295 ? -26.695 -56.718 6.947   1.00 65.17  ? 295 VAL B CB  1 
ATOM   5943  C CG1 . VAL B 1 295 ? -26.062 -57.486 5.793   1.00 67.49  ? 295 VAL B CG1 1 
ATOM   5944  C CG2 . VAL B 1 295 ? -25.668 -55.803 7.587   1.00 63.45  ? 295 VAL B CG2 1 
ATOM   5945  N N   . PRO B 1 296 ? -29.303 -57.052 4.715   1.00 72.43  ? 296 PRO B N   1 
ATOM   5946  C CA  . PRO B 1 296 ? -30.262 -58.038 4.214   1.00 78.60  ? 296 PRO B CA  1 
ATOM   5947  C C   . PRO B 1 296 ? -29.738 -59.470 4.311   1.00 71.84  ? 296 PRO B C   1 
ATOM   5948  O O   . PRO B 1 296 ? -28.534 -59.701 4.411   1.00 72.07  ? 296 PRO B O   1 
ATOM   5949  C CB  . PRO B 1 296 ? -30.516 -57.640 2.748   1.00 72.15  ? 296 PRO B CB  1 
ATOM   5950  C CG  . PRO B 1 296 ? -29.325 -56.781 2.353   1.00 78.83  ? 296 PRO B CG  1 
ATOM   5951  C CD  . PRO B 1 296 ? -28.755 -56.207 3.643   1.00 77.44  ? 296 PRO B CD  1 
ATOM   5952  N N   . THR B 1 297 ? -30.675 -60.418 4.268   1.00 71.58  ? 297 THR B N   1 
ATOM   5953  C CA  . THR B 1 297 ? -30.369 -61.837 4.205   1.00 64.08  ? 297 THR B CA  1 
ATOM   5954  C C   . THR B 1 297 ? -29.903 -62.196 2.792   1.00 70.19  ? 297 THR B C   1 
ATOM   5955  O O   . THR B 1 297 ? -30.099 -61.433 1.831   1.00 58.43  ? 297 THR B O   1 
ATOM   5956  C CB  . THR B 1 297 ? -31.595 -62.664 4.626   1.00 62.41  ? 297 THR B CB  1 
ATOM   5957  O OG1 . THR B 1 297 ? -32.643 -62.415 3.679   1.00 53.32  ? 297 THR B OG1 1 
ATOM   5958  C CG2 . THR B 1 297 ? -32.063 -62.355 6.039   1.00 62.02  ? 297 THR B CG2 1 
ATOM   5959  N N   . LYS B 1 298 ? -29.312 -63.392 2.682   1.00 72.12  ? 298 LYS B N   1 
ATOM   5960  C CA  . LYS B 1 298 ? -28.849 -63.936 1.413   1.00 87.13  ? 298 LYS B CA  1 
ATOM   5961  C C   . LYS B 1 298 ? -30.011 -63.985 0.415   1.00 82.54  ? 298 LYS B C   1 
ATOM   5962  O O   . LYS B 1 298 ? -29.811 -63.808 -0.789  1.00 84.98  ? 298 LYS B O   1 
ATOM   5963  C CB  . LYS B 1 298 ? -28.202 -65.307 1.668   1.00 98.05  ? 298 LYS B CB  1 
ATOM   5964  C CG  . LYS B 1 298 ? -27.466 -65.940 0.493   1.00 104.17 ? 298 LYS B CG  1 
ATOM   5965  C CD  . LYS B 1 298 ? -26.720 -67.218 0.859   1.00 107.80 ? 298 LYS B CD  1 
ATOM   5966  C CE  . LYS B 1 298 ? -26.197 -67.977 -0.345  1.00 102.95 ? 298 LYS B CE  1 
ATOM   5967  N NZ  . LYS B 1 298 ? -27.300 -68.459 -1.214  1.00 97.62  ? 298 LYS B NZ  1 
ATOM   5968  N N   . GLU B 1 299 ? -31.231 -64.183 0.929   1.00 77.34  ? 299 GLU B N   1 
ATOM   5969  C CA  . GLU B 1 299 ? -32.401 -64.404 0.091   1.00 84.83  ? 299 GLU B CA  1 
ATOM   5970  C C   . GLU B 1 299 ? -32.975 -63.076 -0.420  1.00 78.24  ? 299 GLU B C   1 
ATOM   5971  O O   . GLU B 1 299 ? -33.435 -62.986 -1.564  1.00 65.63  ? 299 GLU B O   1 
ATOM   5972  C CB  . GLU B 1 299 ? -33.439 -65.182 0.902   1.00 99.53  ? 299 GLU B CB  1 
ATOM   5973  C CG  . GLU B 1 299 ? -34.542 -65.806 0.068   1.00 103.24 ? 299 GLU B CG  1 
ATOM   5974  C CD  . GLU B 1 299 ? -35.859 -65.951 0.814   1.00 100.77 ? 299 GLU B CD  1 
ATOM   5975  O OE1 . GLU B 1 299 ? -35.871 -66.591 1.897   1.00 89.16  ? 299 GLU B OE1 1 
ATOM   5976  O OE2 . GLU B 1 299 ? -36.864 -65.413 0.313   1.00 89.76  ? 299 GLU B OE2 1 
ATOM   5977  N N   . GLN B 1 300 ? -32.964 -62.038 0.429   1.00 69.98  ? 300 GLN B N   1 
ATOM   5978  C CA  . GLN B 1 300 ? -33.518 -60.747 0.037   1.00 69.57  ? 300 GLN B CA  1 
ATOM   5979  C C   . GLN B 1 300 ? -32.669 -60.102 -1.060  1.00 68.75  ? 300 GLN B C   1 
ATOM   5980  O O   . GLN B 1 300 ? -33.211 -59.439 -1.952  1.00 67.37  ? 300 GLN B O   1 
ATOM   5981  C CB  . GLN B 1 300 ? -33.642 -59.832 1.253   1.00 62.04  ? 300 GLN B CB  1 
ATOM   5982  C CG  . GLN B 1 300 ? -34.633 -60.370 2.271   1.00 65.14  ? 300 GLN B CG  1 
ATOM   5983  C CD  . GLN B 1 300 ? -34.625 -59.602 3.569   1.00 57.84  ? 300 GLN B CD  1 
ATOM   5984  O OE1 . GLN B 1 300 ? -33.574 -59.320 4.153   1.00 56.53  ? 300 GLN B OE1 1 
ATOM   5985  N NE2 . GLN B 1 300 ? -35.818 -59.254 4.026   1.00 51.12  ? 300 GLN B NE2 1 
ATOM   5986  N N   . LEU B 1 301 ? -31.341 -60.289 -0.982  1.00 64.98  ? 301 LEU B N   1 
ATOM   5987  C CA  . LEU B 1 301 ? -30.430 -59.624 -1.900  1.00 64.40  ? 301 LEU B CA  1 
ATOM   5988  C C   . LEU B 1 301 ? -30.591 -60.250 -3.288  1.00 63.48  ? 301 LEU B C   1 
ATOM   5989  O O   . LEU B 1 301 ? -30.637 -59.532 -4.288  1.00 64.73  ? 301 LEU B O   1 
ATOM   5990  C CB  . LEU B 1 301 ? -28.985 -59.688 -1.372  1.00 58.24  ? 301 LEU B CB  1 
ATOM   5991  C CG  . LEU B 1 301 ? -27.945 -58.828 -2.111  1.00 66.88  ? 301 LEU B CG  1 
ATOM   5992  C CD1 . LEU B 1 301 ? -28.241 -57.326 -2.016  1.00 67.49  ? 301 LEU B CD1 1 
ATOM   5993  C CD2 . LEU B 1 301 ? -26.539 -59.108 -1.588  1.00 70.23  ? 301 LEU B CD2 1 
ATOM   5994  N N   . GLU B 1 302 ? -30.730 -61.578 -3.331  1.00 65.66  ? 302 GLU B N   1 
ATOM   5995  C CA  . GLU B 1 302 ? -31.030 -62.297 -4.563  1.00 70.55  ? 302 GLU B CA  1 
ATOM   5996  C C   . GLU B 1 302 ? -32.311 -61.769 -5.213  1.00 69.23  ? 302 GLU B C   1 
ATOM   5997  O O   . GLU B 1 302 ? -32.322 -61.526 -6.421  1.00 71.90  ? 302 GLU B O   1 
ATOM   5998  C CB  . GLU B 1 302 ? -31.172 -63.797 -4.303  1.00 71.51  ? 302 GLU B CB  1 
ATOM   5999  C CG  . GLU B 1 302 ? -29.853 -64.540 -4.246  1.00 76.40  ? 302 GLU B CG  1 
ATOM   6000  C CD  . GLU B 1 302 ? -29.970 -65.914 -3.610  1.00 85.40  ? 302 GLU B CD  1 
ATOM   6001  O OE1 . GLU B 1 302 ? -31.048 -66.531 -3.752  1.00 79.51  ? 302 GLU B OE1 1 
ATOM   6002  O OE2 . GLU B 1 302 ? -28.985 -66.365 -2.981  1.00 93.39  ? 302 GLU B OE2 1 
ATOM   6003  N N   . ARG B 1 303 ? -33.378 -61.584 -4.423  1.00 61.16  ? 303 ARG B N   1 
ATOM   6004  C CA  . ARG B 1 303 ? -34.671 -61.209 -4.977  1.00 70.67  ? 303 ARG B CA  1 
ATOM   6005  C C   . ARG B 1 303 ? -34.591 -59.785 -5.524  1.00 67.18  ? 303 ARG B C   1 
ATOM   6006  O O   . ARG B 1 303 ? -35.020 -59.542 -6.652  1.00 57.78  ? 303 ARG B O   1 
ATOM   6007  C CB  . ARG B 1 303 ? -35.776 -61.389 -3.929  1.00 83.63  ? 303 ARG B CB  1 
ATOM   6008  C CG  . ARG B 1 303 ? -37.144 -60.834 -4.312  1.00 98.42  ? 303 ARG B CG  1 
ATOM   6009  C CD  . ARG B 1 303 ? -38.204 -61.338 -3.340  1.00 111.75 ? 303 ARG B CD  1 
ATOM   6010  N NE  . ARG B 1 303 ? -38.967 -60.275 -2.685  1.00 119.54 ? 303 ARG B NE  1 
ATOM   6011  C CZ  . ARG B 1 303 ? -38.780 -59.842 -1.427  1.00 115.61 ? 303 ARG B CZ  1 
ATOM   6012  N NH1 . ARG B 1 303 ? -37.743 -60.243 -0.698  1.00 94.03  ? 303 ARG B NH1 1 
ATOM   6013  N NH2 . ARG B 1 303 ? -39.625 -58.962 -0.913  1.00 103.65 ? 303 ARG B NH2 1 
ATOM   6014  N N   . PHE B 1 304 ? -34.015 -58.861 -4.733  1.00 75.62  ? 304 PHE B N   1 
ATOM   6015  C CA  . PHE B 1 304 ? -33.802 -57.488 -5.174  1.00 73.23  ? 304 PHE B CA  1 
ATOM   6016  C C   . PHE B 1 304 ? -32.780 -57.425 -6.328  1.00 68.75  ? 304 PHE B C   1 
ATOM   6017  O O   . PHE B 1 304 ? -32.843 -56.509 -7.143  1.00 71.61  ? 304 PHE B O   1 
ATOM   6018  C CB  . PHE B 1 304 ? -33.429 -56.582 -3.992  1.00 78.26  ? 304 PHE B CB  1 
ATOM   6019  C CG  . PHE B 1 304 ? -33.351 -55.112 -4.351  1.00 92.30  ? 304 PHE B CG  1 
ATOM   6020  C CD1 . PHE B 1 304 ? -34.505 -54.370 -4.580  1.00 95.28  ? 304 PHE B CD1 1 
ATOM   6021  C CD2 . PHE B 1 304 ? -32.122 -54.486 -4.549  1.00 91.41  ? 304 PHE B CD2 1 
ATOM   6022  C CE1 . PHE B 1 304 ? -34.432 -53.033 -4.946  1.00 89.43  ? 304 PHE B CE1 1 
ATOM   6023  C CE2 . PHE B 1 304 ? -32.052 -53.149 -4.916  1.00 85.17  ? 304 PHE B CE2 1 
ATOM   6024  C CZ  . PHE B 1 304 ? -33.209 -52.426 -5.108  1.00 84.81  ? 304 PHE B CZ  1 
ATOM   6025  N N   . ALA B 1 305 ? -31.850 -58.393 -6.433  1.00 66.25  ? 305 ALA B N   1 
ATOM   6026  C CA  . ALA B 1 305 ? -30.934 -58.459 -7.567  1.00 73.74  ? 305 ALA B CA  1 
ATOM   6027  C C   . ALA B 1 305 ? -31.663 -58.941 -8.830  1.00 79.05  ? 305 ALA B C   1 
ATOM   6028  O O   . ALA B 1 305 ? -31.390 -58.412 -9.912  1.00 84.05  ? 305 ALA B O   1 
ATOM   6029  C CB  . ALA B 1 305 ? -29.719 -59.315 -7.254  1.00 65.88  ? 305 ALA B CB  1 
ATOM   6030  N N   . TRP B 1 306 ? -32.572 -59.930 -8.696  1.00 75.73  ? 306 TRP B N   1 
ATOM   6031  C CA  . TRP B 1 306 ? -33.346 -60.441 -9.827  1.00 75.90  ? 306 TRP B CA  1 
ATOM   6032  C C   . TRP B 1 306 ? -34.310 -59.369 -10.351 1.00 68.59  ? 306 TRP B C   1 
ATOM   6033  O O   . TRP B 1 306 ? -34.331 -59.143 -11.557 1.00 63.33  ? 306 TRP B O   1 
ATOM   6034  C CB  . TRP B 1 306 ? -34.080 -61.761 -9.505  1.00 73.76  ? 306 TRP B CB  1 
ATOM   6035  C CG  . TRP B 1 306 ? -33.245 -63.005 -9.608  1.00 78.44  ? 306 TRP B CG  1 
ATOM   6036  C CD1 . TRP B 1 306 ? -32.828 -63.801 -8.575  1.00 79.61  ? 306 TRP B CD1 1 
ATOM   6037  C CD2 . TRP B 1 306 ? -32.753 -63.628 -10.812 1.00 75.18  ? 306 TRP B CD2 1 
ATOM   6038  N NE1 . TRP B 1 306 ? -32.081 -64.845 -9.047  1.00 73.71  ? 306 TRP B NE1 1 
ATOM   6039  C CE2 . TRP B 1 306 ? -32.021 -64.771 -10.416 1.00 78.35  ? 306 TRP B CE2 1 
ATOM   6040  C CE3 . TRP B 1 306 ? -32.834 -63.322 -12.177 1.00 71.49  ? 306 TRP B CE3 1 
ATOM   6041  C CZ2 . TRP B 1 306 ? -31.393 -65.613 -11.338 1.00 80.17  ? 306 TRP B CZ2 1 
ATOM   6042  C CZ3 . TRP B 1 306 ? -32.206 -64.147 -13.084 1.00 78.43  ? 306 TRP B CZ3 1 
ATOM   6043  C CH2 . TRP B 1 306 ? -31.499 -65.280 -12.670 1.00 81.94  ? 306 TRP B CH2 1 
ATOM   6044  N N   . ASP B 1 307 ? -35.075 -58.704 -9.459  1.00 67.10  ? 307 ASP B N   1 
ATOM   6045  C CA  . ASP B 1 307 ? -36.015 -57.642 -9.827  1.00 77.66  ? 307 ASP B CA  1 
ATOM   6046  C C   . ASP B 1 307 ? -35.329 -56.549 -10.654 1.00 86.01  ? 307 ASP B C   1 
ATOM   6047  O O   . ASP B 1 307 ? -35.882 -56.107 -11.662 1.00 81.17  ? 307 ASP B O   1 
ATOM   6048  C CB  . ASP B 1 307 ? -36.643 -56.975 -8.595  1.00 84.52  ? 307 ASP B CB  1 
ATOM   6049  C CG  . ASP B 1 307 ? -37.729 -57.779 -7.893  1.00 93.26  ? 307 ASP B CG  1 
ATOM   6050  O OD1 . ASP B 1 307 ? -38.203 -58.769 -8.480  1.00 92.33  ? 307 ASP B OD1 1 
ATOM   6051  O OD2 . ASP B 1 307 ? -38.090 -57.406 -6.750  1.00 89.85  ? 307 ASP B OD2 1 
ATOM   6052  N N   . THR B 1 308 ? -34.142 -56.113 -10.183 1.00 82.07  ? 308 THR B N   1 
ATOM   6053  C CA  . THR B 1 308 ? -33.322 -55.084 -10.809 1.00 75.83  ? 308 THR B CA  1 
ATOM   6054  C C   . THR B 1 308 ? -32.844 -55.521 -12.198 1.00 67.58  ? 308 THR B C   1 
ATOM   6055  O O   . THR B 1 308 ? -32.969 -54.764 -13.152 1.00 69.27  ? 308 THR B O   1 
ATOM   6056  C CB  . THR B 1 308 ? -32.115 -54.729 -9.919  1.00 76.57  ? 308 THR B CB  1 
ATOM   6057  O OG1 . THR B 1 308 ? -32.542 -54.148 -8.687  1.00 71.78  ? 308 THR B OG1 1 
ATOM   6058  C CG2 . THR B 1 308 ? -31.161 -53.746 -10.563 1.00 80.79  ? 308 THR B CG2 1 
ATOM   6059  N N   . LEU B 1 309 ? -32.261 -56.721 -12.314 1.00 57.40  ? 309 LEU B N   1 
ATOM   6060  C CA  . LEU B 1 309 ? -31.780 -57.213 -13.599 1.00 66.04  ? 309 LEU B CA  1 
ATOM   6061  C C   . LEU B 1 309 ? -32.948 -57.439 -14.577 1.00 76.58  ? 309 LEU B C   1 
ATOM   6062  O O   . LEU B 1 309 ? -32.874 -57.024 -15.735 1.00 76.91  ? 309 LEU B O   1 
ATOM   6063  C CB  . LEU B 1 309 ? -30.966 -58.501 -13.394 1.00 62.68  ? 309 LEU B CB  1 
ATOM   6064  C CG  . LEU B 1 309 ? -29.557 -58.346 -12.809 1.00 65.72  ? 309 LEU B CG  1 
ATOM   6065  C CD1 . LEU B 1 309 ? -28.949 -59.709 -12.456 1.00 62.07  ? 309 LEU B CD1 1 
ATOM   6066  C CD2 . LEU B 1 309 ? -28.632 -57.579 -13.764 1.00 66.70  ? 309 LEU B CD2 1 
ATOM   6067  N N   . ASN B 1 310 ? -34.025 -58.106 -14.126 1.00 84.63  ? 310 ASN B N   1 
ATOM   6068  C CA  . ASN B 1 310 ? -35.139 -58.456 -15.003 1.00 89.55  ? 310 ASN B CA  1 
ATOM   6069  C C   . ASN B 1 310 ? -35.832 -57.197 -15.516 1.00 84.22  ? 310 ASN B C   1 
ATOM   6070  O O   . ASN B 1 310 ? -36.439 -57.248 -16.578 1.00 86.44  ? 310 ASN B O   1 
ATOM   6071  C CB  . ASN B 1 310 ? -36.193 -59.357 -14.344 1.00 90.38  ? 310 ASN B CB  1 
ATOM   6072  C CG  . ASN B 1 310 ? -35.715 -60.772 -14.074 1.00 100.86 ? 310 ASN B CG  1 
ATOM   6073  O OD1 . ASN B 1 310 ? -34.939 -61.348 -14.842 1.00 94.05  ? 310 ASN B OD1 1 
ATOM   6074  N ND2 . ASN B 1 310 ? -36.162 -61.338 -12.964 1.00 102.29 ? 310 ASN B ND2 1 
ATOM   6075  N N   . SER B 1 311 ? -35.730 -56.086 -14.766 1.00 87.06  ? 311 SER B N   1 
ATOM   6076  C CA  . SER B 1 311 ? -36.370 -54.831 -15.123 1.00 79.64  ? 311 SER B CA  1 
ATOM   6077  C C   . SER B 1 311 ? -35.462 -53.941 -15.978 1.00 88.06  ? 311 SER B C   1 
ATOM   6078  O O   . SER B 1 311 ? -35.684 -52.737 -15.998 1.00 87.43  ? 311 SER B O   1 
ATOM   6079  C CB  . SER B 1 311 ? -36.846 -54.102 -13.885 1.00 74.12  ? 311 SER B CB  1 
ATOM   6080  O OG  . SER B 1 311 ? -35.794 -53.428 -13.219 1.00 70.74  ? 311 SER B OG  1 
ATOM   6081  N N   . GLY B 1 312 ? -34.457 -54.527 -16.668 1.00 105.91 ? 312 GLY B N   1 
ATOM   6082  C CA  . GLY B 1 312 ? -33.576 -53.822 -17.603 1.00 94.16  ? 312 GLY B CA  1 
ATOM   6083  C C   . GLY B 1 312 ? -32.350 -53.165 -16.949 1.00 94.74  ? 312 GLY B C   1 
ATOM   6084  O O   . GLY B 1 312 ? -31.448 -52.691 -17.645 1.00 69.25  ? 312 GLY B O   1 
ATOM   6085  N N   . GLN B 1 313 ? -32.312 -53.148 -15.606 1.00 98.32  ? 313 GLN B N   1 
ATOM   6086  C CA  . GLN B 1 313 ? -31.383 -52.321 -14.849 1.00 94.08  ? 313 GLN B CA  1 
ATOM   6087  C C   . GLN B 1 313 ? -30.102 -53.098 -14.544 1.00 92.70  ? 313 GLN B C   1 
ATOM   6088  O O   . GLN B 1 313 ? -30.043 -54.329 -14.660 1.00 86.16  ? 313 GLN B O   1 
ATOM   6089  C CB  . GLN B 1 313 ? -32.003 -51.863 -13.524 1.00 97.07  ? 313 GLN B CB  1 
ATOM   6090  C CG  . GLN B 1 313 ? -33.242 -50.994 -13.670 1.00 104.99 ? 313 GLN B CG  1 
ATOM   6091  C CD  . GLN B 1 313 ? -32.898 -49.548 -13.925 1.00 114.72 ? 313 GLN B CD  1 
ATOM   6092  O OE1 . GLN B 1 313 ? -33.058 -48.694 -13.054 1.00 132.36 ? 313 GLN B OE1 1 
ATOM   6093  N NE2 . GLN B 1 313 ? -32.413 -49.262 -15.123 1.00 101.34 ? 313 GLN B NE2 1 
ATOM   6094  N N   . VAL B 1 314 ? -29.088 -52.340 -14.110 1.00 81.61  ? 314 VAL B N   1 
ATOM   6095  C CA  . VAL B 1 314 ? -27.814 -52.911 -13.720 1.00 79.61  ? 314 VAL B CA  1 
ATOM   6096  C C   . VAL B 1 314 ? -27.556 -52.643 -12.234 1.00 81.90  ? 314 VAL B C   1 
ATOM   6097  O O   . VAL B 1 314 ? -28.157 -51.769 -11.585 1.00 66.84  ? 314 VAL B O   1 
ATOM   6098  C CB  . VAL B 1 314 ? -26.676 -52.389 -14.618 1.00 84.00  ? 314 VAL B CB  1 
ATOM   6099  C CG1 . VAL B 1 314 ? -26.803 -52.931 -16.038 1.00 85.22  ? 314 VAL B CG1 1 
ATOM   6100  C CG2 . VAL B 1 314 ? -26.595 -50.867 -14.618 1.00 85.85  ? 314 VAL B CG2 1 
ATOM   6101  N N   . ILE B 1 315 ? -26.650 -53.461 -11.699 1.00 74.50  ? 315 ILE B N   1 
ATOM   6102  C CA  . ILE B 1 315 ? -26.178 -53.329 -10.336 1.00 75.93  ? 315 ILE B CA  1 
ATOM   6103  C C   . ILE B 1 315 ? -24.855 -52.559 -10.387 1.00 76.14  ? 315 ILE B C   1 
ATOM   6104  O O   . ILE B 1 315 ? -23.914 -53.023 -11.040 1.00 58.43  ? 315 ILE B O   1 
ATOM   6105  C CB  . ILE B 1 315 ? -26.037 -54.731 -9.711  1.00 82.05  ? 315 ILE B CB  1 
ATOM   6106  C CG1 . ILE B 1 315 ? -27.382 -55.468 -9.679  1.00 74.26  ? 315 ILE B CG1 1 
ATOM   6107  C CG2 . ILE B 1 315 ? -25.384 -54.645 -8.335  1.00 90.01  ? 315 ILE B CG2 1 
ATOM   6108  C CD1 . ILE B 1 315 ? -27.259 -56.929 -9.988  1.00 78.70  ? 315 ILE B CD1 1 
ATOM   6109  N N   . PRO B 1 316 ? -24.768 -51.363 -9.738  1.00 60.83  ? 316 PRO B N   1 
ATOM   6110  C CA  . PRO B 1 316 ? -23.582 -50.512 -9.809  1.00 52.23  ? 316 PRO B CA  1 
ATOM   6111  C C   . PRO B 1 316 ? -22.302 -51.220 -9.358  1.00 52.99  ? 316 PRO B C   1 
ATOM   6112  O O   . PRO B 1 316 ? -22.340 -52.071 -8.469  1.00 54.10  ? 316 PRO B O   1 
ATOM   6113  C CB  . PRO B 1 316 ? -23.906 -49.346 -8.864  1.00 62.33  ? 316 PRO B CB  1 
ATOM   6114  C CG  . PRO B 1 316 ? -25.418 -49.320 -8.781  1.00 58.10  ? 316 PRO B CG  1 
ATOM   6115  C CD  . PRO B 1 316 ? -25.842 -50.762 -8.931  1.00 56.30  ? 316 PRO B CD  1 
ATOM   6116  N N   . GLY B 1 317 ? -21.206 -50.948 -10.084 1.00 49.65  ? 317 GLY B N   1 
ATOM   6117  C CA  . GLY B 1 317 ? -19.888 -51.522 -9.850  1.00 49.67  ? 317 GLY B CA  1 
ATOM   6118  C C   . GLY B 1 317 ? -19.712 -53.007 -10.178 1.00 51.97  ? 317 GLY B C   1 
ATOM   6119  O O   . GLY B 1 317 ? -18.608 -53.532 -9.966  1.00 50.08  ? 317 GLY B O   1 
ATOM   6120  N N   . TYR B 1 318 ? -20.744 -53.662 -10.741 1.00 52.54  ? 318 TYR B N   1 
ATOM   6121  C CA  . TYR B 1 318 ? -20.636 -55.036 -11.225 1.00 54.66  ? 318 TYR B CA  1 
ATOM   6122  C C   . TYR B 1 318 ? -20.937 -55.127 -12.722 1.00 63.74  ? 318 TYR B C   1 
ATOM   6123  O O   . TYR B 1 318 ? -21.875 -54.498 -13.219 1.00 59.19  ? 318 TYR B O   1 
ATOM   6124  C CB  . TYR B 1 318 ? -21.630 -55.944 -10.495 1.00 56.92  ? 318 TYR B CB  1 
ATOM   6125  C CG  . TYR B 1 318 ? -21.182 -56.443 -9.142  1.00 57.30  ? 318 TYR B CG  1 
ATOM   6126  C CD1 . TYR B 1 318 ? -21.353 -55.672 -7.998  1.00 52.66  ? 318 TYR B CD1 1 
ATOM   6127  C CD2 . TYR B 1 318 ? -20.575 -57.695 -9.003  1.00 53.55  ? 318 TYR B CD2 1 
ATOM   6128  C CE1 . TYR B 1 318 ? -20.945 -56.134 -6.747  1.00 55.31  ? 318 TYR B CE1 1 
ATOM   6129  C CE2 . TYR B 1 318 ? -20.183 -58.174 -7.756  1.00 52.55  ? 318 TYR B CE2 1 
ATOM   6130  C CZ  . TYR B 1 318 ? -20.359 -57.389 -6.626  1.00 49.67  ? 318 TYR B CZ  1 
ATOM   6131  O OH  . TYR B 1 318 ? -19.911 -57.838 -5.411  1.00 49.18  ? 318 TYR B OH  1 
ATOM   6132  N N   . GLY B 1 319 ? -20.170 -55.965 -13.428 1.00 63.72  ? 319 GLY B N   1 
ATOM   6133  C CA  . GLY B 1 319 ? -20.511 -56.349 -14.790 1.00 69.51  ? 319 GLY B CA  1 
ATOM   6134  C C   . GLY B 1 319 ? -20.092 -55.344 -15.869 1.00 76.19  ? 319 GLY B C   1 
ATOM   6135  O O   . GLY B 1 319 ? -20.767 -55.217 -16.890 1.00 81.89  ? 319 GLY B O   1 
ATOM   6136  N N   . HIS B 1 320 ? -18.972 -54.638 -15.678 1.00 83.11  ? 320 HIS B N   1 
ATOM   6137  C CA  . HIS B 1 320 ? -18.382 -53.905 -16.788 1.00 92.05  ? 320 HIS B CA  1 
ATOM   6138  C C   . HIS B 1 320 ? -17.897 -54.888 -17.859 1.00 87.45  ? 320 HIS B C   1 
ATOM   6139  O O   . HIS B 1 320 ? -17.751 -56.082 -17.611 1.00 96.44  ? 320 HIS B O   1 
ATOM   6140  C CB  . HIS B 1 320 ? -17.325 -52.895 -16.320 1.00 95.41  ? 320 HIS B CB  1 
ATOM   6141  C CG  . HIS B 1 320 ? -17.729 -51.473 -16.589 1.00 105.12 ? 320 HIS B CG  1 
ATOM   6142  N ND1 . HIS B 1 320 ? -17.450 -50.820 -17.782 1.00 95.89  ? 320 HIS B ND1 1 
ATOM   6143  C CD2 . HIS B 1 320 ? -18.456 -50.622 -15.844 1.00 96.55  ? 320 HIS B CD2 1 
ATOM   6144  C CE1 . HIS B 1 320 ? -17.955 -49.600 -17.733 1.00 103.83 ? 320 HIS B CE1 1 
ATOM   6145  N NE2 . HIS B 1 320 ? -18.567 -49.459 -16.565 1.00 108.38 ? 320 HIS B NE2 1 
ATOM   6146  N N   . ALA B 1 321 ? -17.660 -54.367 -19.065 1.00 92.00  ? 321 ALA B N   1 
ATOM   6147  C CA  . ALA B 1 321 ? -17.587 -55.191 -20.264 1.00 99.86  ? 321 ALA B CA  1 
ATOM   6148  C C   . ALA B 1 321 ? -16.291 -55.999 -20.298 1.00 101.46 ? 321 ALA B C   1 
ATOM   6149  O O   . ALA B 1 321 ? -16.316 -57.170 -20.677 1.00 90.55  ? 321 ALA B O   1 
ATOM   6150  C CB  . ALA B 1 321 ? -17.729 -54.328 -21.501 1.00 86.34  ? 321 ALA B CB  1 
ATOM   6151  N N   . VAL B 1 322 ? -15.187 -55.374 -19.859 1.00 91.41  ? 322 VAL B N   1 
ATOM   6152  C CA  . VAL B 1 322 ? -13.865 -55.710 -20.367 1.00 93.72  ? 322 VAL B CA  1 
ATOM   6153  C C   . VAL B 1 322 ? -13.316 -56.979 -19.708 1.00 97.29  ? 322 VAL B C   1 
ATOM   6154  O O   . VAL B 1 322 ? -12.887 -57.905 -20.399 1.00 90.53  ? 322 VAL B O   1 
ATOM   6155  C CB  . VAL B 1 322 ? -12.892 -54.535 -20.170 1.00 98.41  ? 322 VAL B CB  1 
ATOM   6156  C CG1 . VAL B 1 322 ? -11.540 -54.848 -20.802 1.00 99.38  ? 322 VAL B CG1 1 
ATOM   6157  C CG2 . VAL B 1 322 ? -13.463 -53.218 -20.688 1.00 93.47  ? 322 VAL B CG2 1 
ATOM   6158  N N   . LEU B 1 323 ? -13.287 -56.996 -18.369 1.00 90.26  ? 323 LEU B N   1 
ATOM   6159  C CA  . LEU B 1 323 ? -12.592 -58.039 -17.626 1.00 85.04  ? 323 LEU B CA  1 
ATOM   6160  C C   . LEU B 1 323 ? -13.401 -59.332 -17.653 1.00 78.84  ? 323 LEU B C   1 
ATOM   6161  O O   . LEU B 1 323 ? -14.605 -59.313 -17.902 1.00 72.38  ? 323 LEU B O   1 
ATOM   6162  C CB  . LEU B 1 323 ? -12.356 -57.577 -16.176 1.00 80.67  ? 323 LEU B CB  1 
ATOM   6163  C CG  . LEU B 1 323 ? -11.236 -56.555 -15.949 1.00 77.14  ? 323 LEU B CG  1 
ATOM   6164  C CD1 . LEU B 1 323 ? -10.955 -56.371 -14.468 1.00 67.76  ? 323 LEU B CD1 1 
ATOM   6165  C CD2 . LEU B 1 323 ? -9.950  -56.953 -16.669 1.00 75.21  ? 323 LEU B CD2 1 
ATOM   6166  N N   . ARG B 1 324 ? -12.718 -60.447 -17.371 1.00 74.27  ? 324 ARG B N   1 
ATOM   6167  C CA  . ARG B 1 324 ? -13.387 -61.725 -17.177 1.00 84.95  ? 324 ARG B CA  1 
ATOM   6168  C C   . ARG B 1 324 ? -13.102 -62.285 -15.776 1.00 80.87  ? 324 ARG B C   1 
ATOM   6169  O O   . ARG B 1 324 ? -13.506 -63.407 -15.461 1.00 82.70  ? 324 ARG B O   1 
ATOM   6170  C CB  . ARG B 1 324 ? -12.988 -62.700 -18.294 1.00 87.09  ? 324 ARG B CB  1 
ATOM   6171  C CG  . ARG B 1 324 ? -13.533 -62.329 -19.667 1.00 92.49  ? 324 ARG B CG  1 
ATOM   6172  C CD  . ARG B 1 324 ? -13.321 -63.412 -20.717 1.00 107.89 ? 324 ARG B CD  1 
ATOM   6173  N NE  . ARG B 1 324 ? -11.963 -63.962 -20.748 1.00 105.86 ? 324 ARG B NE  1 
ATOM   6174  C CZ  . ARG B 1 324 ? -11.027 -63.658 -21.649 1.00 99.21  ? 324 ARG B CZ  1 
ATOM   6175  N NH1 . ARG B 1 324 ? -11.231 -62.691 -22.529 1.00 92.82  ? 324 ARG B NH1 1 
ATOM   6176  N NH2 . ARG B 1 324 ? -9.868  -64.298 -21.647 1.00 90.83  ? 324 ARG B NH2 1 
ATOM   6177  N N   . VAL B 1 325 ? -12.434 -61.496 -14.922 1.00 75.37  ? 325 VAL B N   1 
ATOM   6178  C CA  . VAL B 1 325 ? -12.247 -61.839 -13.519 1.00 65.13  ? 325 VAL B CA  1 
ATOM   6179  C C   . VAL B 1 325 ? -12.543 -60.613 -12.640 1.00 63.60  ? 325 VAL B C   1 
ATOM   6180  O O   . VAL B 1 325 ? -12.768 -59.505 -13.119 1.00 73.60  ? 325 VAL B O   1 
ATOM   6181  C CB  . VAL B 1 325 ? -10.828 -62.387 -13.265 1.00 67.28  ? 325 VAL B CB  1 
ATOM   6182  C CG1 . VAL B 1 325 ? -10.531 -63.632 -14.103 1.00 62.82  ? 325 VAL B CG1 1 
ATOM   6183  C CG2 . VAL B 1 325 ? -9.763  -61.317 -13.477 1.00 70.56  ? 325 VAL B CG2 1 
ATOM   6184  N N   . THR B 1 326 ? -12.558 -60.832 -11.327 1.00 64.22  ? 326 THR B N   1 
ATOM   6185  C CA  . THR B 1 326 ? -12.673 -59.774 -10.348 1.00 57.28  ? 326 THR B CA  1 
ATOM   6186  C C   . THR B 1 326 ? -11.518 -58.789 -10.487 1.00 48.75  ? 326 THR B C   1 
ATOM   6187  O O   . THR B 1 326 ? -10.358 -59.194 -10.547 1.00 51.18  ? 326 THR B O   1 
ATOM   6188  C CB  . THR B 1 326 ? -12.704 -60.353 -8.929  1.00 62.15  ? 326 THR B CB  1 
ATOM   6189  O OG1 . THR B 1 326 ? -13.946 -61.049 -8.836  1.00 62.39  ? 326 THR B OG1 1 
ATOM   6190  C CG2 . THR B 1 326 ? -12.606 -59.300 -7.837  1.00 63.83  ? 326 THR B CG2 1 
ATOM   6191  N N   . ASP B 1 327 ? -11.862 -57.495 -10.450 1.00 50.27  ? 327 ASP B N   1 
ATOM   6192  C CA  . ASP B 1 327 ? -10.906 -56.408 -10.564 1.00 45.17  ? 327 ASP B CA  1 
ATOM   6193  C C   . ASP B 1 327 ? -9.916  -56.566 -9.419  1.00 50.55  ? 327 ASP B C   1 
ATOM   6194  O O   . ASP B 1 327 ? -10.333 -56.622 -8.251  1.00 43.96  ? 327 ASP B O   1 
ATOM   6195  C CB  . ASP B 1 327 ? -11.676 -55.092 -10.555 1.00 54.07  ? 327 ASP B CB  1 
ATOM   6196  C CG  . ASP B 1 327 ? -10.840 -53.829 -10.717 1.00 60.46  ? 327 ASP B CG  1 
ATOM   6197  O OD1 . ASP B 1 327 ? -9.586  -53.930 -10.602 1.00 55.31  ? 327 ASP B OD1 1 
ATOM   6198  O OD2 . ASP B 1 327 ? -11.460 -52.741 -10.968 1.00 49.78  ? 327 ASP B OD2 1 
ATOM   6199  N N   . PRO B 1 328 ? -8.594  -56.695 -9.703  1.00 43.29  ? 328 PRO B N   1 
ATOM   6200  C CA  . PRO B 1 328 ? -7.611  -56.888 -8.633  1.00 49.84  ? 328 PRO B CA  1 
ATOM   6201  C C   . PRO B 1 328 ? -7.510  -55.684 -7.682  1.00 56.82  ? 328 PRO B C   1 
ATOM   6202  O O   . PRO B 1 328 ? -6.943  -55.806 -6.577  1.00 54.07  ? 328 PRO B O   1 
ATOM   6203  C CB  . PRO B 1 328 ? -6.277  -57.192 -9.371  1.00 51.24  ? 328 PRO B CB  1 
ATOM   6204  C CG  . PRO B 1 328 ? -6.482  -56.666 -10.796 1.00 48.87  ? 328 PRO B CG  1 
ATOM   6205  C CD  . PRO B 1 328 ? -7.986  -56.711 -11.048 1.00 47.93  ? 328 PRO B CD  1 
ATOM   6206  N N   . ARG B 1 329 ? -8.057  -54.527 -8.115  1.00 49.42  ? 329 ARG B N   1 
ATOM   6207  C CA  . ARG B 1 329 ? -8.227  -53.387 -7.220  1.00 57.53  ? 329 ARG B CA  1 
ATOM   6208  C C   . ARG B 1 329 ? -9.361  -53.649 -6.225  1.00 60.64  ? 329 ARG B C   1 
ATOM   6209  O O   . ARG B 1 329 ? -9.251  -53.223 -5.071  1.00 55.45  ? 329 ARG B O   1 
ATOM   6210  C CB  . ARG B 1 329 ? -8.466  -52.069 -7.966  1.00 52.71  ? 329 ARG B CB  1 
ATOM   6211  C CG  . ARG B 1 329 ? -7.324  -51.709 -8.905  1.00 62.06  ? 329 ARG B CG  1 
ATOM   6212  C CD  . ARG B 1 329 ? -7.643  -50.584 -9.865  1.00 60.04  ? 329 ARG B CD  1 
ATOM   6213  N NE  . ARG B 1 329 ? -8.826  -50.841 -10.672 1.00 56.50  ? 329 ARG B NE  1 
ATOM   6214  C CZ  . ARG B 1 329 ? -9.243  -50.069 -11.665 1.00 59.43  ? 329 ARG B CZ  1 
ATOM   6215  N NH1 . ARG B 1 329 ? -8.513  -49.034 -12.052 1.00 52.73  ? 329 ARG B NH1 1 
ATOM   6216  N NH2 . ARG B 1 329 ? -10.382 -50.352 -12.279 1.00 62.08  ? 329 ARG B NH2 1 
ATOM   6217  N N   . TYR B 1 330 ? -10.432 -54.336 -6.663  1.00 56.25  ? 330 TYR B N   1 
ATOM   6218  C CA  . TYR B 1 330 ? -11.465 -54.796 -5.737  1.00 55.18  ? 330 TYR B CA  1 
ATOM   6219  C C   . TYR B 1 330 ? -10.923 -55.735 -4.658  1.00 46.58  ? 330 TYR B C   1 
ATOM   6220  O O   . TYR B 1 330 ? -11.214 -55.532 -3.488  1.00 42.01  ? 330 TYR B O   1 
ATOM   6221  C CB  . TYR B 1 330 ? -12.579 -55.535 -6.462  1.00 49.79  ? 330 TYR B CB  1 
ATOM   6222  C CG  . TYR B 1 330 ? -13.734 -55.906 -5.582  1.00 51.38  ? 330 TYR B CG  1 
ATOM   6223  C CD1 . TYR B 1 330 ? -13.704 -57.075 -4.828  1.00 49.48  ? 330 TYR B CD1 1 
ATOM   6224  C CD2 . TYR B 1 330 ? -14.875 -55.115 -5.529  1.00 51.55  ? 330 TYR B CD2 1 
ATOM   6225  C CE1 . TYR B 1 330 ? -14.787 -57.462 -4.046  1.00 50.53  ? 330 TYR B CE1 1 
ATOM   6226  C CE2 . TYR B 1 330 ? -15.970 -55.496 -4.759  1.00 61.42  ? 330 TYR B CE2 1 
ATOM   6227  C CZ  . TYR B 1 330 ? -15.932 -56.674 -4.015  1.00 55.26  ? 330 TYR B CZ  1 
ATOM   6228  O OH  . TYR B 1 330 ? -17.007 -57.047 -3.230  1.00 51.76  ? 330 TYR B OH  1 
ATOM   6229  N N   . VAL B 1 331 ? -10.156 -56.753 -5.075  1.00 49.69  ? 331 VAL B N   1 
ATOM   6230  C CA  . VAL B 1 331 ? -9.647  -57.806 -4.203  1.00 52.38  ? 331 VAL B CA  1 
ATOM   6231  C C   . VAL B 1 331 ? -8.805  -57.181 -3.082  1.00 55.26  ? 331 VAL B C   1 
ATOM   6232  O O   . VAL B 1 331 ? -8.941  -57.549 -1.903  1.00 46.15  ? 331 VAL B O   1 
ATOM   6233  C CB  . VAL B 1 331 ? -8.833  -58.864 -4.990  1.00 60.23  ? 331 VAL B CB  1 
ATOM   6234  C CG1 . VAL B 1 331 ? -8.369  -60.016 -4.105  1.00 57.92  ? 331 VAL B CG1 1 
ATOM   6235  C CG2 . VAL B 1 331 ? -9.594  -59.429 -6.190  1.00 63.17  ? 331 VAL B CG2 1 
ATOM   6236  N N   . ALA B 1 332 ? -7.939  -56.219 -3.435  1.00 51.54  ? 332 ALA B N   1 
ATOM   6237  C CA  . ALA B 1 332 ? -7.065  -55.619 -2.434  1.00 60.44  ? 332 ALA B CA  1 
ATOM   6238  C C   . ALA B 1 332 ? -7.856  -54.806 -1.391  1.00 62.82  ? 332 ALA B C   1 
ATOM   6239  O O   . ALA B 1 332 ? -7.436  -54.734 -0.230  1.00 55.46  ? 332 ALA B O   1 
ATOM   6240  C CB  . ALA B 1 332 ? -6.007  -54.798 -3.107  1.00 56.60  ? 332 ALA B CB  1 
ATOM   6241  N N   . GLN B 1 333 ? -8.998  -54.217 -1.799  1.00 57.53  ? 333 GLN B N   1 
ATOM   6242  C CA  . GLN B 1 333 ? -9.862  -53.458 -0.897  1.00 61.80  ? 333 GLN B CA  1 
ATOM   6243  C C   . GLN B 1 333 ? -10.627 -54.403 0.021   1.00 52.50  ? 333 GLN B C   1 
ATOM   6244  O O   . GLN B 1 333 ? -10.848 -54.084 1.199   1.00 46.33  ? 333 GLN B O   1 
ATOM   6245  C CB  . GLN B 1 333 ? -10.851 -52.557 -1.650  1.00 56.76  ? 333 GLN B CB  1 
ATOM   6246  C CG  . GLN B 1 333 ? -10.174 -51.368 -2.322  1.00 57.47  ? 333 GLN B CG  1 
ATOM   6247  C CD  . GLN B 1 333 ? -11.107 -50.574 -3.202  1.00 56.74  ? 333 GLN B CD  1 
ATOM   6248  O OE1 . GLN B 1 333 ? -11.395 -50.914 -4.351  1.00 60.76  ? 333 GLN B OE1 1 
ATOM   6249  N NE2 . GLN B 1 333 ? -11.586 -49.486 -2.647  1.00 50.59  ? 333 GLN B NE2 1 
ATOM   6250  N N   . ARG B 1 334 ? -11.027 -55.557 -0.526  1.00 53.39  ? 334 ARG B N   1 
ATOM   6251  C CA  . ARG B 1 334 ? -11.716 -56.567 0.269   1.00 51.73  ? 334 ARG B CA  1 
ATOM   6252  C C   . ARG B 1 334 ? -10.797 -56.983 1.416   1.00 44.45  ? 334 ARG B C   1 
ATOM   6253  O O   . ARG B 1 334 ? -11.182 -56.936 2.585   1.00 44.15  ? 334 ARG B O   1 
ATOM   6254  C CB  . ARG B 1 334 ? -12.120 -57.736 -0.631  1.00 56.68  ? 334 ARG B CB  1 
ATOM   6255  C CG  . ARG B 1 334 ? -12.704 -58.925 0.113   1.00 59.76  ? 334 ARG B CG  1 
ATOM   6256  C CD  . ARG B 1 334 ? -13.556 -59.821 -0.765  1.00 65.09  ? 334 ARG B CD  1 
ATOM   6257  N NE  . ARG B 1 334 ? -14.024 -60.998 -0.038  1.00 71.74  ? 334 ARG B NE  1 
ATOM   6258  C CZ  . ARG B 1 334 ? -15.035 -61.051 0.835   1.00 69.88  ? 334 ARG B CZ  1 
ATOM   6259  N NH1 . ARG B 1 334 ? -15.862 -60.031 1.016   1.00 62.90  ? 334 ARG B NH1 1 
ATOM   6260  N NH2 . ARG B 1 334 ? -15.245 -62.177 1.496   1.00 70.17  ? 334 ARG B NH2 1 
ATOM   6261  N N   . ASP B 1 335 ? -9.560  -57.343 1.058   1.00 43.75  ? 335 ASP B N   1 
ATOM   6262  C CA  . ASP B 1 335 ? -8.564  -57.787 2.024   1.00 49.89  ? 335 ASP B CA  1 
ATOM   6263  C C   . ASP B 1 335 ? -8.299  -56.693 3.066   1.00 53.19  ? 335 ASP B C   1 
ATOM   6264  O O   . ASP B 1 335 ? -8.033  -57.014 4.223   1.00 52.97  ? 335 ASP B O   1 
ATOM   6265  C CB  . ASP B 1 335 ? -7.280  -58.257 1.337   1.00 49.70  ? 335 ASP B CB  1 
ATOM   6266  C CG  . ASP B 1 335 ? -6.169  -58.639 2.306   1.00 59.37  ? 335 ASP B CG  1 
ATOM   6267  O OD1 . ASP B 1 335 ? -6.294  -59.704 2.978   1.00 64.82  ? 335 ASP B OD1 1 
ATOM   6268  O OD2 . ASP B 1 335 ? -5.191  -57.851 2.412   1.00 56.31  ? 335 ASP B OD2 1 
ATOM   6269  N N   . PHE B 1 336 ? -8.365  -55.401 2.672   1.00 57.65  ? 336 PHE B N   1 
ATOM   6270  C CA  . PHE B 1 336 ? -8.170  -54.315 3.623   1.00 49.30  ? 336 PHE B CA  1 
ATOM   6271  C C   . PHE B 1 336 ? -9.343  -54.233 4.604   1.00 52.03  ? 336 PHE B C   1 
ATOM   6272  O O   . PHE B 1 336 ? -9.121  -54.079 5.813   1.00 47.21  ? 336 PHE B O   1 
ATOM   6273  C CB  . PHE B 1 336 ? -7.949  -52.986 2.905   1.00 49.93  ? 336 PHE B CB  1 
ATOM   6274  C CG  . PHE B 1 336 ? -7.758  -51.826 3.849   1.00 44.28  ? 336 PHE B CG  1 
ATOM   6275  C CD1 . PHE B 1 336 ? -8.851  -51.237 4.469   1.00 44.89  ? 336 PHE B CD1 1 
ATOM   6276  C CD2 . PHE B 1 336 ? -6.479  -51.359 4.146   1.00 46.33  ? 336 PHE B CD2 1 
ATOM   6277  C CE1 . PHE B 1 336 ? -8.680  -50.162 5.341   1.00 48.65  ? 336 PHE B CE1 1 
ATOM   6278  C CE2 . PHE B 1 336 ? -6.300  -50.307 5.038   1.00 48.00  ? 336 PHE B CE2 1 
ATOM   6279  C CZ  . PHE B 1 336 ? -7.401  -49.704 5.621   1.00 51.88  ? 336 PHE B CZ  1 
ATOM   6280  N N   . ALA B 1 337 ? -10.581 -54.296 4.065   1.00 43.33  ? 337 ALA B N   1 
ATOM   6281  C CA  . ALA B 1 337 ? -11.800 -54.321 4.859   1.00 39.97  ? 337 ALA B CA  1 
ATOM   6282  C C   . ALA B 1 337 ? -11.825 -55.511 5.847   1.00 49.45  ? 337 ALA B C   1 
ATOM   6283  O O   . ALA B 1 337 ? -12.127 -55.331 7.033   1.00 45.20  ? 337 ALA B O   1 
ATOM   6284  C CB  . ALA B 1 337 ? -13.004 -54.310 3.924   1.00 36.49  ? 337 ALA B CB  1 
ATOM   6285  N N   . LEU B 1 338 ? -11.566 -56.748 5.377   1.00 50.89  ? 338 LEU B N   1 
ATOM   6286  C CA  . LEU B 1 338 ? -11.633 -57.922 6.242   1.00 56.69  ? 338 LEU B CA  1 
ATOM   6287  C C   . LEU B 1 338 ? -10.704 -57.707 7.443   1.00 61.81  ? 338 LEU B C   1 
ATOM   6288  O O   . LEU B 1 338 ? -11.132 -57.796 8.585   1.00 66.93  ? 338 LEU B O   1 
ATOM   6289  C CB  . LEU B 1 338 ? -11.244 -59.174 5.433   1.00 62.77  ? 338 LEU B CB  1 
ATOM   6290  C CG  . LEU B 1 338 ? -12.227 -59.594 4.330   1.00 67.94  ? 338 LEU B CG  1 
ATOM   6291  C CD1 . LEU B 1 338 ? -11.619 -60.617 3.369   1.00 63.43  ? 338 LEU B CD1 1 
ATOM   6292  C CD2 . LEU B 1 338 ? -13.530 -60.135 4.931   1.00 62.58  ? 338 LEU B CD2 1 
ATOM   6293  N N   . LYS B 1 339 ? -9.453  -57.313 7.171   1.00 59.58  ? 339 LYS B N   1 
ATOM   6294  C CA  . LYS B 1 339 ? -8.452  -57.040 8.195   1.00 68.16  ? 339 LYS B CA  1 
ATOM   6295  C C   . LYS B 1 339 ? -8.936  -55.966 9.188   1.00 67.11  ? 339 LYS B C   1 
ATOM   6296  O O   . LYS B 1 339 ? -8.866  -56.179 10.398  1.00 65.29  ? 339 LYS B O   1 
ATOM   6297  C CB  . LYS B 1 339 ? -7.138  -56.663 7.493   1.00 77.04  ? 339 LYS B CB  1 
ATOM   6298  C CG  . LYS B 1 339 ? -5.854  -57.204 8.119   1.00 95.49  ? 339 LYS B CG  1 
ATOM   6299  C CD  . LYS B 1 339 ? -4.597  -57.011 7.251   1.00 103.19 ? 339 LYS B CD  1 
ATOM   6300  C CE  . LYS B 1 339 ? -4.687  -57.648 5.871   1.00 98.80  ? 339 LYS B CE  1 
ATOM   6301  N NZ  . LYS B 1 339 ? -3.372  -57.720 5.175   1.00 86.84  ? 339 LYS B NZ  1 
ATOM   6302  N N   . HIS B 1 340 ? -9.470  -54.838 8.682   1.00 58.83  ? 340 HIS B N   1 
ATOM   6303  C CA  . HIS B 1 340 ? -9.509  -53.575 9.412   1.00 51.64  ? 340 HIS B CA  1 
ATOM   6304  C C   . HIS B 1 340 ? -10.905 -53.154 9.882   1.00 51.25  ? 340 HIS B C   1 
ATOM   6305  O O   . HIS B 1 340 ? -11.006 -52.580 10.957  1.00 55.05  ? 340 HIS B O   1 
ATOM   6306  C CB  . HIS B 1 340 ? -8.928  -52.450 8.556   1.00 49.53  ? 340 HIS B CB  1 
ATOM   6307  C CG  . HIS B 1 340 ? -7.458  -52.564 8.387   1.00 53.96  ? 340 HIS B CG  1 
ATOM   6308  N ND1 . HIS B 1 340 ? -6.587  -52.534 9.450   1.00 57.50  ? 340 HIS B ND1 1 
ATOM   6309  C CD2 . HIS B 1 340 ? -6.704  -52.713 7.279   1.00 55.06  ? 340 HIS B CD2 1 
ATOM   6310  C CE1 . HIS B 1 340 ? -5.351  -52.652 8.983   1.00 62.50  ? 340 HIS B CE1 1 
ATOM   6311  N NE2 . HIS B 1 340 ? -5.406  -52.738 7.660   1.00 53.29  ? 340 HIS B NE2 1 
ATOM   6312  N N   . LEU B 1 341 ? -11.968 -53.411 9.098   1.00 48.67  ? 341 LEU B N   1 
ATOM   6313  C CA  . LEU B 1 341 ? -13.321 -53.033 9.498   1.00 46.70  ? 341 LEU B CA  1 
ATOM   6314  C C   . LEU B 1 341 ? -14.355 -54.098 9.144   1.00 47.18  ? 341 LEU B C   1 
ATOM   6315  O O   . LEU B 1 341 ? -15.409 -53.768 8.593   1.00 49.19  ? 341 LEU B O   1 
ATOM   6316  C CB  . LEU B 1 341 ? -13.657 -51.711 8.803   1.00 49.16  ? 341 LEU B CB  1 
ATOM   6317  C CG  . LEU B 1 341 ? -13.507 -51.727 7.286   1.00 47.80  ? 341 LEU B CG  1 
ATOM   6318  C CD1 . LEU B 1 341 ? -14.805 -51.290 6.601   1.00 44.21  ? 341 LEU B CD1 1 
ATOM   6319  C CD2 . LEU B 1 341 ? -12.310 -50.899 6.846   1.00 49.61  ? 341 LEU B CD2 1 
ATOM   6320  N N   . PRO B 1 342 ? -14.138 -55.381 9.533   1.00 56.51  ? 342 PRO B N   1 
ATOM   6321  C CA  . PRO B 1 342 ? -15.012 -56.489 9.121   1.00 59.43  ? 342 PRO B CA  1 
ATOM   6322  C C   . PRO B 1 342 ? -16.464 -56.464 9.620   1.00 60.22  ? 342 PRO B C   1 
ATOM   6323  O O   . PRO B 1 342 ? -17.355 -57.043 8.987   1.00 60.09  ? 342 PRO B O   1 
ATOM   6324  C CB  . PRO B 1 342 ? -14.275 -57.730 9.682   1.00 67.70  ? 342 PRO B CB  1 
ATOM   6325  C CG  . PRO B 1 342 ? -13.487 -57.198 10.872  1.00 66.35  ? 342 PRO B CG  1 
ATOM   6326  C CD  . PRO B 1 342 ? -13.035 -55.833 10.401  1.00 64.26  ? 342 PRO B CD  1 
ATOM   6327  N N   . ASP B 1 343 ? -16.708 -55.787 10.749  1.00 62.11  ? 343 ASP B N   1 
ATOM   6328  C CA  . ASP B 1 343 ? -18.025 -55.754 11.376  1.00 67.25  ? 343 ASP B CA  1 
ATOM   6329  C C   . ASP B 1 343 ? -18.840 -54.525 10.941  1.00 69.67  ? 343 ASP B C   1 
ATOM   6330  O O   . ASP B 1 343 ? -20.010 -54.410 11.296  1.00 67.37  ? 343 ASP B O   1 
ATOM   6331  C CB  . ASP B 1 343 ? -17.879 -55.820 12.905  1.00 75.74  ? 343 ASP B CB  1 
ATOM   6332  C CG  . ASP B 1 343 ? -17.150 -57.068 13.400  1.00 80.49  ? 343 ASP B CG  1 
ATOM   6333  O OD1 . ASP B 1 343 ? -17.418 -58.162 12.841  1.00 65.47  ? 343 ASP B OD1 1 
ATOM   6334  O OD2 . ASP B 1 343 ? -16.343 -56.957 14.361  1.00 75.04  ? 343 ASP B OD2 1 
ATOM   6335  N N   . ASP B 1 344 ? -18.241 -53.605 10.169  1.00 71.65  ? 344 ASP B N   1 
ATOM   6336  C CA  . ASP B 1 344 ? -18.975 -52.464 9.637   1.00 67.97  ? 344 ASP B CA  1 
ATOM   6337  C C   . ASP B 1 344 ? -20.145 -52.976 8.785   1.00 60.59  ? 344 ASP B C   1 
ATOM   6338  O O   . ASP B 1 344 ? -19.989 -53.840 7.916   1.00 50.91  ? 344 ASP B O   1 
ATOM   6339  C CB  . ASP B 1 344 ? -18.047 -51.512 8.868   1.00 63.07  ? 344 ASP B CB  1 
ATOM   6340  C CG  . ASP B 1 344 ? -18.735 -50.239 8.394   1.00 71.87  ? 344 ASP B CG  1 
ATOM   6341  O OD1 . ASP B 1 344 ? -19.649 -50.347 7.518   1.00 64.37  ? 344 ASP B OD1 1 
ATOM   6342  O OD2 . ASP B 1 344 ? -18.365 -49.132 8.912   1.00 77.99  ? 344 ASP B OD2 1 
ATOM   6343  N N   . GLU B 1 345 ? -21.321 -52.394 9.014   1.00 54.10  ? 345 GLU B N   1 
ATOM   6344  C CA  . GLU B 1 345 ? -22.542 -52.925 8.444   1.00 60.41  ? 345 GLU B CA  1 
ATOM   6345  C C   . GLU B 1 345 ? -22.574 -52.719 6.931   1.00 56.35  ? 345 GLU B C   1 
ATOM   6346  O O   . GLU B 1 345 ? -22.948 -53.645 6.220   1.00 54.49  ? 345 GLU B O   1 
ATOM   6347  C CB  . GLU B 1 345 ? -23.753 -52.337 9.163   1.00 69.43  ? 345 GLU B CB  1 
ATOM   6348  C CG  . GLU B 1 345 ? -23.957 -52.949 10.553  1.00 77.24  ? 345 GLU B CG  1 
ATOM   6349  C CD  . GLU B 1 345 ? -25.318 -52.674 11.183  1.00 86.38  ? 345 GLU B CD  1 
ATOM   6350  O OE1 . GLU B 1 345 ? -26.327 -53.351 10.816  1.00 79.77  ? 345 GLU B OE1 1 
ATOM   6351  O OE2 . GLU B 1 345 ? -25.378 -51.747 12.018  1.00 97.84  ? 345 GLU B OE2 1 
ATOM   6352  N N   . LEU B 1 346 ? -22.161 -51.545 6.427   1.00 50.13  ? 346 LEU B N   1 
ATOM   6353  C CA  . LEU B 1 346 ? -22.198 -51.305 4.985   1.00 50.90  ? 346 LEU B CA  1 
ATOM   6354  C C   . LEU B 1 346 ? -21.189 -52.228 4.302   1.00 45.19  ? 346 LEU B C   1 
ATOM   6355  O O   . LEU B 1 346 ? -21.480 -52.760 3.242   1.00 53.46  ? 346 LEU B O   1 
ATOM   6356  C CB  . LEU B 1 346 ? -21.957 -49.817 4.665   1.00 47.56  ? 346 LEU B CB  1 
ATOM   6357  C CG  . LEU B 1 346 ? -22.978 -48.819 5.230   1.00 51.30  ? 346 LEU B CG  1 
ATOM   6358  C CD1 . LEU B 1 346 ? -22.633 -47.405 4.786   1.00 55.90  ? 346 LEU B CD1 1 
ATOM   6359  C CD2 . LEU B 1 346 ? -24.416 -49.152 4.826   1.00 46.74  ? 346 LEU B CD2 1 
ATOM   6360  N N   . PHE B 1 347 ? -20.044 -52.492 4.947   1.00 50.42  ? 347 PHE B N   1 
ATOM   6361  C CA  . PHE B 1 347 ? -19.072 -53.451 4.422   1.00 61.34  ? 347 PHE B CA  1 
ATOM   6362  C C   . PHE B 1 347 ? -19.655 -54.856 4.254   1.00 64.25  ? 347 PHE B C   1 
ATOM   6363  O O   . PHE B 1 347 ? -19.332 -55.519 3.250   1.00 50.59  ? 347 PHE B O   1 
ATOM   6364  C CB  . PHE B 1 347 ? -17.825 -53.617 5.305   1.00 64.96  ? 347 PHE B CB  1 
ATOM   6365  C CG  . PHE B 1 347 ? -16.948 -54.769 4.859   1.00 64.65  ? 347 PHE B CG  1 
ATOM   6366  C CD1 . PHE B 1 347 ? -16.480 -54.836 3.549   1.00 69.14  ? 347 PHE B CD1 1 
ATOM   6367  C CD2 . PHE B 1 347 ? -16.668 -55.827 5.710   1.00 56.99  ? 347 PHE B CD2 1 
ATOM   6368  C CE1 . PHE B 1 347 ? -15.727 -55.915 3.114   1.00 66.90  ? 347 PHE B CE1 1 
ATOM   6369  C CE2 . PHE B 1 347 ? -15.904 -56.898 5.276   1.00 58.94  ? 347 PHE B CE2 1 
ATOM   6370  C CZ  . PHE B 1 347 ? -15.419 -56.934 3.989   1.00 65.17  ? 347 PHE B CZ  1 
ATOM   6371  N N   . LYS B 1 348 ? -20.417 -55.296 5.280   1.00 56.69  ? 348 LYS B N   1 
ATOM   6372  C CA  . LYS B 1 348 ? -21.138 -56.565 5.274   1.00 60.60  ? 348 LYS B CA  1 
ATOM   6373  C C   . LYS B 1 348 ? -22.060 -56.679 4.064   1.00 55.62  ? 348 LYS B C   1 
ATOM   6374  O O   . LYS B 1 348 ? -22.243 -57.789 3.570   1.00 60.75  ? 348 LYS B O   1 
ATOM   6375  C CB  . LYS B 1 348 ? -22.001 -56.748 6.530   1.00 60.80  ? 348 LYS B CB  1 
ATOM   6376  C CG  . LYS B 1 348 ? -21.222 -56.905 7.824   1.00 68.95  ? 348 LYS B CG  1 
ATOM   6377  C CD  . LYS B 1 348 ? -22.063 -57.248 9.030   1.00 80.93  ? 348 LYS B CD  1 
ATOM   6378  C CE  . LYS B 1 348 ? -21.238 -57.892 10.129  1.00 86.53  ? 348 LYS B CE  1 
ATOM   6379  N NZ  . LYS B 1 348 ? -22.052 -58.167 11.336  1.00 83.22  ? 348 LYS B NZ  1 
ATOM   6380  N N   . ILE B 1 349 ? -22.659 -55.562 3.612   1.00 56.39  ? 349 ILE B N   1 
ATOM   6381  C CA  . ILE B 1 349 ? -23.540 -55.602 2.442   1.00 60.03  ? 349 ILE B CA  1 
ATOM   6382  C C   . ILE B 1 349 ? -22.704 -55.819 1.174   1.00 55.90  ? 349 ILE B C   1 
ATOM   6383  O O   . ILE B 1 349 ? -23.062 -56.637 0.333   1.00 43.85  ? 349 ILE B O   1 
ATOM   6384  C CB  . ILE B 1 349 ? -24.441 -54.351 2.317   1.00 55.21  ? 349 ILE B CB  1 
ATOM   6385  C CG1 . ILE B 1 349 ? -25.343 -54.177 3.546   1.00 54.24  ? 349 ILE B CG1 1 
ATOM   6386  C CG2 . ILE B 1 349 ? -25.243 -54.425 1.018   1.00 57.30  ? 349 ILE B CG2 1 
ATOM   6387  C CD1 . ILE B 1 349 ? -26.418 -53.112 3.419   1.00 51.81  ? 349 ILE B CD1 1 
ATOM   6388  N N   . VAL B 1 350 ? -21.604 -55.054 1.055   1.00 60.92  ? 350 VAL B N   1 
ATOM   6389  C CA  . VAL B 1 350 ? -20.659 -55.163 -0.054  1.00 56.62  ? 350 VAL B CA  1 
ATOM   6390  C C   . VAL B 1 350 ? -20.117 -56.599 -0.074  1.00 52.98  ? 350 VAL B C   1 
ATOM   6391  O O   . VAL B 1 350 ? -19.964 -57.215 -1.119  1.00 45.91  ? 350 VAL B O   1 
ATOM   6392  C CB  . VAL B 1 350 ? -19.527 -54.109 0.071   1.00 54.13  ? 350 VAL B CB  1 
ATOM   6393  C CG1 . VAL B 1 350 ? -18.294 -54.464 -0.751  1.00 56.44  ? 350 VAL B CG1 1 
ATOM   6394  C CG2 . VAL B 1 350 ? -19.986 -52.694 -0.269  1.00 55.05  ? 350 VAL B CG2 1 
ATOM   6395  N N   . SER B 1 351 ? -19.811 -57.125 1.114   1.00 56.74  ? 351 SER B N   1 
ATOM   6396  C CA  . SER B 1 351 ? -19.267 -58.466 1.243   1.00 59.17  ? 351 SER B CA  1 
ATOM   6397  C C   . SER B 1 351 ? -20.300 -59.467 0.739   1.00 56.90  ? 351 SER B C   1 
ATOM   6398  O O   . SER B 1 351 ? -19.982 -60.351 -0.055  1.00 52.98  ? 351 SER B O   1 
ATOM   6399  C CB  . SER B 1 351 ? -18.862 -58.758 2.669   1.00 50.09  ? 351 SER B CB  1 
ATOM   6400  O OG  . SER B 1 351 ? -17.774 -59.644 2.684   1.00 55.38  ? 351 SER B OG  1 
ATOM   6401  N N   . LEU B 1 352 ? -21.532 -59.299 1.237   1.00 53.89  ? 352 LEU B N   1 
ATOM   6402  C CA  . LEU B 1 352 ? -22.649 -60.121 0.823   1.00 56.54  ? 352 LEU B CA  1 
ATOM   6403  C C   . LEU B 1 352 ? -22.837 -60.029 -0.692  1.00 52.42  ? 352 LEU B C   1 
ATOM   6404  O O   . LEU B 1 352 ? -23.161 -61.033 -1.295  1.00 51.22  ? 352 LEU B O   1 
ATOM   6405  C CB  . LEU B 1 352 ? -23.906 -59.667 1.569   1.00 52.73  ? 352 LEU B CB  1 
ATOM   6406  C CG  . LEU B 1 352 ? -25.147 -60.518 1.345   1.00 59.70  ? 352 LEU B CG  1 
ATOM   6407  C CD1 . LEU B 1 352 ? -24.946 -61.925 1.902   1.00 59.90  ? 352 LEU B CD1 1 
ATOM   6408  C CD2 . LEU B 1 352 ? -26.366 -59.858 1.976   1.00 66.56  ? 352 LEU B CD2 1 
ATOM   6409  N N   . CYS B 1 353 ? -22.649 -58.842 -1.289  1.00 47.65  ? 353 CYS B N   1 
ATOM   6410  C CA  . CYS B 1 353 ? -22.792 -58.674 -2.731  1.00 61.10  ? 353 CYS B CA  1 
ATOM   6411  C C   . CYS B 1 353 ? -21.755 -59.508 -3.504  1.00 56.28  ? 353 CYS B C   1 
ATOM   6412  O O   . CYS B 1 353 ? -22.122 -60.133 -4.502  1.00 59.35  ? 353 CYS B O   1 
ATOM   6413  C CB  . CYS B 1 353 ? -22.727 -57.200 -3.143  1.00 61.94  ? 353 CYS B CB  1 
ATOM   6414  S SG  . CYS B 1 353 ? -24.199 -56.256 -2.665  1.00 63.27  ? 353 CYS B SG  1 
ATOM   6415  N N   . TYR B 1 354 ? -20.490 -59.541 -3.041  1.00 49.77  ? 354 TYR B N   1 
ATOM   6416  C CA  . TYR B 1 354 ? -19.419 -60.312 -3.671  1.00 53.43  ? 354 TYR B CA  1 
ATOM   6417  C C   . TYR B 1 354 ? -19.752 -61.808 -3.778  1.00 60.94  ? 354 TYR B C   1 
ATOM   6418  O O   . TYR B 1 354 ? -19.356 -62.471 -4.746  1.00 53.09  ? 354 TYR B O   1 
ATOM   6419  C CB  . TYR B 1 354 ? -18.122 -60.210 -2.869  1.00 55.36  ? 354 TYR B CB  1 
ATOM   6420  C CG  . TYR B 1 354 ? -16.880 -60.665 -3.599  1.00 55.31  ? 354 TYR B CG  1 
ATOM   6421  C CD1 . TYR B 1 354 ? -16.790 -60.554 -4.975  1.00 52.41  ? 354 TYR B CD1 1 
ATOM   6422  C CD2 . TYR B 1 354 ? -15.783 -61.168 -2.918  1.00 61.11  ? 354 TYR B CD2 1 
ATOM   6423  C CE1 . TYR B 1 354 ? -15.649 -60.925 -5.654  1.00 52.63  ? 354 TYR B CE1 1 
ATOM   6424  C CE2 . TYR B 1 354 ? -14.626 -61.554 -3.588  1.00 64.39  ? 354 TYR B CE2 1 
ATOM   6425  C CZ  . TYR B 1 354 ? -14.566 -61.437 -4.968  1.00 62.36  ? 354 TYR B CZ  1 
ATOM   6426  O OH  . TYR B 1 354 ? -13.486 -61.804 -5.736  1.00 62.91  ? 354 TYR B OH  1 
ATOM   6427  N N   . GLU B 1 355 ? -20.452 -62.336 -2.764  1.00 56.21  ? 355 GLU B N   1 
ATOM   6428  C CA  . GLU B 1 355 ? -21.009 -63.681 -2.811  1.00 71.49  ? 355 GLU B CA  1 
ATOM   6429  C C   . GLU B 1 355 ? -22.184 -63.737 -3.800  1.00 66.46  ? 355 GLU B C   1 
ATOM   6430  O O   . GLU B 1 355 ? -22.199 -64.567 -4.710  1.00 73.59  ? 355 GLU B O   1 
ATOM   6431  C CB  . GLU B 1 355 ? -21.459 -64.142 -1.414  1.00 72.57  ? 355 GLU B CB  1 
ATOM   6432  C CG  . GLU B 1 355 ? -21.989 -65.573 -1.388  1.00 77.47  ? 355 GLU B CG  1 
ATOM   6433  C CD  . GLU B 1 355 ? -22.469 -66.089 -0.040  1.00 89.14  ? 355 GLU B CD  1 
ATOM   6434  O OE1 . GLU B 1 355 ? -22.762 -67.316 0.054   1.00 88.29  ? 355 GLU B OE1 1 
ATOM   6435  O OE2 . GLU B 1 355 ? -22.552 -65.271 0.909   1.00 73.56  ? 355 GLU B OE2 1 
ATOM   6436  N N   . VAL B 1 356 ? -23.189 -62.879 -3.597  1.00 55.15  ? 356 VAL B N   1 
ATOM   6437  C CA  . VAL B 1 356 ? -24.510 -63.082 -4.189  1.00 61.91  ? 356 VAL B CA  1 
ATOM   6438  C C   . VAL B 1 356 ? -24.583 -62.560 -5.629  1.00 61.27  ? 356 VAL B C   1 
ATOM   6439  O O   . VAL B 1 356 ? -25.217 -63.189 -6.473  1.00 56.62  ? 356 VAL B O   1 
ATOM   6440  C CB  . VAL B 1 356 ? -25.614 -62.432 -3.335  1.00 53.20  ? 356 VAL B CB  1 
ATOM   6441  C CG1 . VAL B 1 356 ? -26.952 -62.434 -4.055  1.00 50.33  ? 356 VAL B CG1 1 
ATOM   6442  C CG2 . VAL B 1 356 ? -25.726 -63.092 -1.969  1.00 56.65  ? 356 VAL B CG2 1 
ATOM   6443  N N   . ILE B 1 357 ? -23.967 -61.403 -5.909  1.00 59.80  ? 357 ILE B N   1 
ATOM   6444  C CA  . ILE B 1 357 ? -24.268 -60.690 -7.139  1.00 57.06  ? 357 ILE B CA  1 
ATOM   6445  C C   . ILE B 1 357 ? -23.632 -61.400 -8.331  1.00 53.72  ? 357 ILE B C   1 
ATOM   6446  O O   . ILE B 1 357 ? -24.272 -61.466 -9.378  1.00 51.01  ? 357 ILE B O   1 
ATOM   6447  C CB  . ILE B 1 357 ? -23.894 -59.194 -7.071  1.00 58.28  ? 357 ILE B CB  1 
ATOM   6448  C CG1 . ILE B 1 357 ? -24.647 -58.453 -5.959  1.00 45.61  ? 357 ILE B CG1 1 
ATOM   6449  C CG2 . ILE B 1 357 ? -24.120 -58.546 -8.434  1.00 61.28  ? 357 ILE B CG2 1 
ATOM   6450  C CD1 . ILE B 1 357 ? -26.108 -58.286 -6.222  1.00 50.13  ? 357 ILE B CD1 1 
ATOM   6451  N N   . PRO B 1 358 ? -22.381 -61.928 -8.246  1.00 67.99  ? 358 PRO B N   1 
ATOM   6452  C CA  . PRO B 1 358 ? -21.819 -62.758 -9.320  1.00 66.91  ? 358 PRO B CA  1 
ATOM   6453  C C   . PRO B 1 358 ? -22.614 -64.013 -9.670  1.00 68.48  ? 358 PRO B C   1 
ATOM   6454  O O   . PRO B 1 358 ? -22.608 -64.415 -10.831 1.00 69.98  ? 358 PRO B O   1 
ATOM   6455  C CB  . PRO B 1 358 ? -20.427 -63.152 -8.784  1.00 63.13  ? 358 PRO B CB  1 
ATOM   6456  C CG  . PRO B 1 358 ? -20.069 -61.986 -7.887  1.00 65.13  ? 358 PRO B CG  1 
ATOM   6457  C CD  . PRO B 1 358 ? -21.379 -61.662 -7.192  1.00 69.00  ? 358 PRO B CD  1 
ATOM   6458  N N   . GLU B 1 359 ? -23.270 -64.632 -8.672  1.00 73.38  ? 359 GLU B N   1 
ATOM   6459  C CA  . GLU B 1 359 ? -24.048 -65.846 -8.897  1.00 82.49  ? 359 GLU B CA  1 
ATOM   6460  C C   . GLU B 1 359 ? -25.304 -65.523 -9.712  1.00 80.32  ? 359 GLU B C   1 
ATOM   6461  O O   . GLU B 1 359 ? -25.640 -66.278 -10.618 1.00 73.56  ? 359 GLU B O   1 
ATOM   6462  C CB  . GLU B 1 359 ? -24.415 -66.548 -7.582  1.00 86.65  ? 359 GLU B CB  1 
ATOM   6463  C CG  . GLU B 1 359 ? -23.265 -67.325 -6.947  1.00 100.65 ? 359 GLU B CG  1 
ATOM   6464  C CD  . GLU B 1 359 ? -22.730 -68.538 -7.704  1.00 107.60 ? 359 GLU B CD  1 
ATOM   6465  O OE1 . GLU B 1 359 ? -21.837 -69.218 -7.157  1.00 109.68 ? 359 GLU B OE1 1 
ATOM   6466  O OE2 . GLU B 1 359 ? -23.190 -68.809 -8.833  1.00 107.32 ? 359 GLU B OE2 1 
ATOM   6467  N N   . VAL B 1 360 ? -25.964 -64.393 -9.402  1.00 76.75  ? 360 VAL B N   1 
ATOM   6468  C CA  . VAL B 1 360 ? -27.203 -63.979 -10.053 1.00 74.11  ? 360 VAL B CA  1 
ATOM   6469  C C   . VAL B 1 360 ? -26.938 -63.475 -11.473 1.00 72.87  ? 360 VAL B C   1 
ATOM   6470  O O   . VAL B 1 360 ? -27.844 -63.501 -12.306 1.00 63.04  ? 360 VAL B O   1 
ATOM   6471  C CB  . VAL B 1 360 ? -27.923 -62.894 -9.227  1.00 70.42  ? 360 VAL B CB  1 
ATOM   6472  C CG1 . VAL B 1 360 ? -29.100 -62.291 -9.986  1.00 65.57  ? 360 VAL B CG1 1 
ATOM   6473  C CG2 . VAL B 1 360 ? -28.361 -63.420 -7.862  1.00 76.42  ? 360 VAL B CG2 1 
ATOM   6474  N N   . LEU B 1 361 ? -25.725 -62.949 -11.714 1.00 74.08  ? 361 LEU B N   1 
ATOM   6475  C CA  . LEU B 1 361 ? -25.331 -62.436 -13.021 1.00 78.41  ? 361 LEU B CA  1 
ATOM   6476  C C   . LEU B 1 361 ? -25.070 -63.609 -13.975 1.00 69.80  ? 361 LEU B C   1 
ATOM   6477  O O   . LEU B 1 361 ? -25.468 -63.542 -15.133 1.00 75.07  ? 361 LEU B O   1 
ATOM   6478  C CB  . LEU B 1 361 ? -24.080 -61.543 -12.889 1.00 79.03  ? 361 LEU B CB  1 
ATOM   6479  C CG  . LEU B 1 361 ? -24.307 -60.066 -12.554 1.00 81.95  ? 361 LEU B CG  1 
ATOM   6480  C CD1 . LEU B 1 361 ? -22.983 -59.334 -12.315 1.00 68.90  ? 361 LEU B CD1 1 
ATOM   6481  C CD2 . LEU B 1 361 ? -25.105 -59.375 -13.657 1.00 81.28  ? 361 LEU B CD2 1 
ATOM   6482  N N   . LYS B 1 362 ? -24.404 -64.670 -13.486 1.00 67.01  ? 362 LYS B N   1 
ATOM   6483  C CA  . LYS B 1 362 ? -24.110 -65.873 -14.267 1.00 76.02  ? 362 LYS B CA  1 
ATOM   6484  C C   . LYS B 1 362 ? -25.402 -66.580 -14.674 1.00 73.94  ? 362 LYS B C   1 
ATOM   6485  O O   . LYS B 1 362 ? -25.513 -67.093 -15.788 1.00 79.95  ? 362 LYS B O   1 
ATOM   6486  C CB  . LYS B 1 362 ? -23.264 -66.880 -13.477 1.00 78.45  ? 362 LYS B CB  1 
ATOM   6487  C CG  . LYS B 1 362 ? -21.785 -66.548 -13.321 1.00 85.34  ? 362 LYS B CG  1 
ATOM   6488  C CD  . LYS B 1 362 ? -21.089 -67.486 -12.349 1.00 86.94  ? 362 LYS B CD  1 
ATOM   6489  C CE  . LYS B 1 362 ? -19.591 -67.295 -12.300 1.00 85.24  ? 362 LYS B CE  1 
ATOM   6490  N NZ  . LYS B 1 362 ? -19.029 -67.959 -11.106 1.00 84.78  ? 362 LYS B NZ  1 
ATOM   6491  N N   . LYS B 1 363 ? -26.370 -66.579 -13.751 1.00 64.76  ? 363 LYS B N   1 
ATOM   6492  C CA  . LYS B 1 363 ? -27.668 -67.195 -13.950 1.00 71.22  ? 363 LYS B CA  1 
ATOM   6493  C C   . LYS B 1 363 ? -28.556 -66.324 -14.845 1.00 64.27  ? 363 LYS B C   1 
ATOM   6494  O O   . LYS B 1 363 ? -29.520 -66.811 -15.411 1.00 63.12  ? 363 LYS B O   1 
ATOM   6495  C CB  . LYS B 1 363 ? -28.280 -67.484 -12.569 1.00 75.36  ? 363 LYS B CB  1 
ATOM   6496  C CG  . LYS B 1 363 ? -27.516 -68.528 -11.750 1.00 80.52  ? 363 LYS B CG  1 
ATOM   6497  C CD  . LYS B 1 363 ? -28.001 -68.717 -10.313 1.00 84.41  ? 363 LYS B CD  1 
ATOM   6498  C CE  . LYS B 1 363 ? -27.234 -69.801 -9.575  1.00 88.36  ? 363 LYS B CE  1 
ATOM   6499  N NZ  . LYS B 1 363 ? -27.967 -70.290 -8.379  1.00 87.20  ? 363 LYS B NZ  1 
ATOM   6500  N N   . HIS B 1 364 ? -28.236 -65.037 -14.985 1.00 71.41  ? 364 HIS B N   1 
ATOM   6501  C CA  . HIS B 1 364 ? -29.051 -64.136 -15.777 1.00 75.33  ? 364 HIS B CA  1 
ATOM   6502  C C   . HIS B 1 364 ? -28.531 -64.122 -17.216 1.00 80.16  ? 364 HIS B C   1 
ATOM   6503  O O   . HIS B 1 364 ? -29.277 -63.783 -18.127 1.00 78.19  ? 364 HIS B O   1 
ATOM   6504  C CB  . HIS B 1 364 ? -29.138 -62.768 -15.092 1.00 75.63  ? 364 HIS B CB  1 
ATOM   6505  C CG  . HIS B 1 364 ? -30.105 -61.843 -15.746 1.00 80.55  ? 364 HIS B CG  1 
ATOM   6506  N ND1 . HIS B 1 364 ? -31.469 -61.929 -15.560 1.00 75.13  ? 364 HIS B ND1 1 
ATOM   6507  C CD2 . HIS B 1 364 ? -29.897 -60.810 -16.578 1.00 78.60  ? 364 HIS B CD2 1 
ATOM   6508  C CE1 . HIS B 1 364 ? -32.057 -60.970 -16.257 1.00 84.22  ? 364 HIS B CE1 1 
ATOM   6509  N NE2 . HIS B 1 364 ? -31.119 -60.286 -16.889 1.00 87.32  ? 364 HIS B NE2 1 
ATOM   6510  N N   . GLY B 1 365 ? -27.243 -64.446 -17.405 1.00 95.21  ? 365 GLY B N   1 
ATOM   6511  C CA  . GLY B 1 365 ? -26.747 -65.007 -18.659 1.00 119.42 ? 365 GLY B CA  1 
ATOM   6512  C C   . GLY B 1 365 ? -26.433 -63.984 -19.756 1.00 134.96 ? 365 GLY B C   1 
ATOM   6513  O O   . GLY B 1 365 ? -26.206 -64.361 -20.911 1.00 118.37 ? 365 GLY B O   1 
ATOM   6514  N N   . LYS B 1 366 ? -26.403 -62.695 -19.388 1.00 157.36 ? 366 LYS B N   1 
ATOM   6515  C CA  . LYS B 1 366 ? -26.227 -61.607 -20.341 1.00 158.07 ? 366 LYS B CA  1 
ATOM   6516  C C   . LYS B 1 366 ? -24.773 -61.130 -20.328 1.00 159.59 ? 366 LYS B C   1 
ATOM   6517  O O   . LYS B 1 366 ? -24.137 -61.077 -21.382 1.00 144.96 ? 366 LYS B O   1 
ATOM   6518  C CB  . LYS B 1 366 ? -27.199 -60.466 -20.012 1.00 157.54 ? 366 LYS B CB  1 
ATOM   6519  C CG  . LYS B 1 366 ? -28.669 -60.739 -20.323 1.00 151.62 ? 366 LYS B CG  1 
ATOM   6520  C CD  . LYS B 1 366 ? -29.105 -60.294 -21.707 1.00 140.52 ? 366 LYS B CD  1 
ATOM   6521  C CE  . LYS B 1 366 ? -28.226 -60.815 -22.826 1.00 119.94 ? 366 LYS B CE  1 
ATOM   6522  N NZ  . LYS B 1 366 ? -28.636 -60.273 -24.140 1.00 108.23 ? 366 LYS B NZ  1 
ATOM   6523  N N   . ALA B 1 367 ? -24.271 -60.792 -19.126 1.00 159.35 ? 367 ALA B N   1 
ATOM   6524  C CA  . ALA B 1 367 ? -22.944 -60.218 -18.938 1.00 149.71 ? 367 ALA B CA  1 
ATOM   6525  C C   . ALA B 1 367 ? -21.889 -61.324 -18.900 1.00 134.09 ? 367 ALA B C   1 
ATOM   6526  O O   . ALA B 1 367 ? -21.939 -62.217 -18.055 1.00 123.87 ? 367 ALA B O   1 
ATOM   6527  C CB  . ALA B 1 367 ? -22.911 -59.386 -17.671 1.00 145.78 ? 367 ALA B CB  1 
ATOM   6528  N N   . LYS B 1 368 ? -20.916 -61.238 -19.815 1.00 128.36 ? 368 LYS B N   1 
ATOM   6529  C CA  . LYS B 1 368 ? -19.784 -62.153 -19.827 1.00 121.30 ? 368 LYS B CA  1 
ATOM   6530  C C   . LYS B 1 368 ? -18.908 -61.900 -18.598 1.00 113.06 ? 368 LYS B C   1 
ATOM   6531  O O   . LYS B 1 368 ? -18.105 -62.758 -18.240 1.00 106.01 ? 368 LYS B O   1 
ATOM   6532  C CB  . LYS B 1 368 ? -18.987 -62.010 -21.130 1.00 111.67 ? 368 LYS B CB  1 
ATOM   6533  N N   . ASN B 1 369 ? -19.051 -60.719 -17.968 1.00 104.03 ? 369 ASN B N   1 
ATOM   6534  C CA  . ASN B 1 369 ? -18.405 -60.437 -16.693 1.00 96.67  ? 369 ASN B CA  1 
ATOM   6535  C C   . ASN B 1 369 ? -19.444 -60.334 -15.574 1.00 82.80  ? 369 ASN B C   1 
ATOM   6536  O O   . ASN B 1 369 ? -20.242 -59.397 -15.520 1.00 71.24  ? 369 ASN B O   1 
ATOM   6537  C CB  . ASN B 1 369 ? -17.548 -59.163 -16.688 1.00 90.05  ? 369 ASN B CB  1 
ATOM   6538  C CG  . ASN B 1 369 ? -16.658 -59.089 -15.453 1.00 87.00  ? 369 ASN B CG  1 
ATOM   6539  O OD1 . ASN B 1 369 ? -16.224 -60.119 -14.930 1.00 79.40  ? 369 ASN B OD1 1 
ATOM   6540  N ND2 . ASN B 1 369 ? -16.395 -57.890 -14.955 1.00 69.02  ? 369 ASN B ND2 1 
ATOM   6541  N N   . PRO B 1 370 ? -19.458 -61.297 -14.627 1.00 72.54  ? 370 PRO B N   1 
ATOM   6542  C CA  . PRO B 1 370 ? -20.293 -61.178 -13.425 1.00 73.80  ? 370 PRO B CA  1 
ATOM   6543  C C   . PRO B 1 370 ? -19.620 -60.517 -12.217 1.00 70.10  ? 370 PRO B C   1 
ATOM   6544  O O   . PRO B 1 370 ? -20.223 -60.422 -11.151 1.00 63.37  ? 370 PRO B O   1 
ATOM   6545  C CB  . PRO B 1 370 ? -20.593 -62.650 -13.122 1.00 71.44  ? 370 PRO B CB  1 
ATOM   6546  C CG  . PRO B 1 370 ? -19.340 -63.398 -13.582 1.00 77.79  ? 370 PRO B CG  1 
ATOM   6547  C CD  . PRO B 1 370 ? -18.728 -62.575 -14.702 1.00 68.68  ? 370 PRO B CD  1 
ATOM   6548  N N   . TRP B 1 371 ? -18.371 -60.060 -12.401 1.00 64.02  ? 371 TRP B N   1 
ATOM   6549  C CA  . TRP B 1 371 ? -17.491 -59.692 -11.303 1.00 67.22  ? 371 TRP B CA  1 
ATOM   6550  C C   . TRP B 1 371 ? -17.429 -58.168 -11.076 1.00 55.10  ? 371 TRP B C   1 
ATOM   6551  O O   . TRP B 1 371 ? -17.601 -57.355 -11.976 1.00 60.74  ? 371 TRP B O   1 
ATOM   6552  C CB  . TRP B 1 371 ? -16.103 -60.290 -11.583 1.00 71.14  ? 371 TRP B CB  1 
ATOM   6553  C CG  . TRP B 1 371 ? -16.076 -61.787 -11.644 1.00 80.71  ? 371 TRP B CG  1 
ATOM   6554  C CD1 . TRP B 1 371 ? -15.692 -62.575 -12.696 1.00 83.69  ? 371 TRP B CD1 1 
ATOM   6555  C CD2 . TRP B 1 371 ? -16.432 -62.685 -10.580 1.00 68.18  ? 371 TRP B CD2 1 
ATOM   6556  N NE1 . TRP B 1 371 ? -15.789 -63.899 -12.359 1.00 79.56  ? 371 TRP B NE1 1 
ATOM   6557  C CE2 . TRP B 1 371 ? -16.232 -63.996 -11.064 1.00 76.64  ? 371 TRP B CE2 1 
ATOM   6558  C CE3 . TRP B 1 371 ? -16.877 -62.504 -9.268  1.00 65.43  ? 371 TRP B CE3 1 
ATOM   6559  C CZ2 . TRP B 1 371 ? -16.485 -65.121 -10.279 1.00 71.37  ? 371 TRP B CZ2 1 
ATOM   6560  C CZ3 . TRP B 1 371 ? -17.114 -63.618 -8.491  1.00 72.01  ? 371 TRP B CZ3 1 
ATOM   6561  C CH2 . TRP B 1 371 ? -16.927 -64.907 -8.993  1.00 69.92  ? 371 TRP B CH2 1 
ATOM   6562  N N   . PRO B 1 372 ? -17.125 -57.696 -9.857  1.00 54.84  ? 372 PRO B N   1 
ATOM   6563  C CA  . PRO B 1 372 ? -17.017 -56.255 -9.624  1.00 61.38  ? 372 PRO B CA  1 
ATOM   6564  C C   . PRO B 1 372 ? -15.743 -55.564 -10.136 1.00 58.71  ? 372 PRO B C   1 
ATOM   6565  O O   . PRO B 1 372 ? -14.774 -56.228 -10.521 1.00 53.75  ? 372 PRO B O   1 
ATOM   6566  C CB  . PRO B 1 372 ? -17.092 -56.199 -8.089  1.00 60.72  ? 372 PRO B CB  1 
ATOM   6567  C CG  . PRO B 1 372 ? -16.417 -57.480 -7.634  1.00 63.53  ? 372 PRO B CG  1 
ATOM   6568  C CD  . PRO B 1 372 ? -16.843 -58.504 -8.662  1.00 57.48  ? 372 PRO B CD  1 
ATOM   6569  N N   . ASN B 1 373 ? -15.777 -54.211 -10.121 1.00 63.16  ? 373 ASN B N   1 
ATOM   6570  C CA  . ASN B 1 373 ? -14.603 -53.359 -10.282 1.00 55.74  ? 373 ASN B CA  1 
ATOM   6571  C C   . ASN B 1 373 ? -14.254 -52.645 -8.959  1.00 57.30  ? 373 ASN B C   1 
ATOM   6572  O O   . ASN B 1 373 ? -14.838 -52.880 -7.903  1.00 59.71  ? 373 ASN B O   1 
ATOM   6573  C CB  . ASN B 1 373 ? -14.756 -52.392 -11.471 1.00 59.91  ? 373 ASN B CB  1 
ATOM   6574  C CG  . ASN B 1 373 ? -15.873 -51.360 -11.358 1.00 61.36  ? 373 ASN B CG  1 
ATOM   6575  O OD1 . ASN B 1 373 ? -15.999 -50.642 -10.373 1.00 59.52  ? 373 ASN B OD1 1 
ATOM   6576  N ND2 . ASN B 1 373 ? -16.691 -51.242 -12.390 1.00 72.98  ? 373 ASN B ND2 1 
ATOM   6577  N N   . VAL B 1 374 ? -13.251 -51.768 -9.042  1.00 60.98  ? 374 VAL B N   1 
ATOM   6578  C CA  . VAL B 1 374 ? -12.700 -50.987 -7.948  1.00 63.36  ? 374 VAL B CA  1 
ATOM   6579  C C   . VAL B 1 374 ? -13.748 -50.098 -7.260  1.00 57.54  ? 374 VAL B C   1 
ATOM   6580  O O   . VAL B 1 374 ? -13.727 -49.950 -6.036  1.00 45.96  ? 374 VAL B O   1 
ATOM   6581  C CB  . VAL B 1 374 ? -11.524 -50.136 -8.477  1.00 66.66  ? 374 VAL B CB  1 
ATOM   6582  C CG1 . VAL B 1 374 ? -11.973 -49.080 -9.490  1.00 67.93  ? 374 VAL B CG1 1 
ATOM   6583  C CG2 . VAL B 1 374 ? -10.752 -49.493 -7.337  1.00 65.43  ? 374 VAL B CG2 1 
ATOM   6584  N N   . ASP B 1 375 ? -14.675 -49.524 -8.026  1.00 52.50  ? 375 ASP B N   1 
ATOM   6585  C CA  . ASP B 1 375 ? -15.604 -48.533 -7.495  1.00 58.08  ? 375 ASP B CA  1 
ATOM   6586  C C   . ASP B 1 375 ? -16.707 -49.167 -6.634  1.00 61.26  ? 375 ASP B C   1 
ATOM   6587  O O   . ASP B 1 375 ? -17.532 -48.454 -6.044  1.00 53.43  ? 375 ASP B O   1 
ATOM   6588  C CB  . ASP B 1 375 ? -16.164 -47.694 -8.647  1.00 59.73  ? 375 ASP B CB  1 
ATOM   6589  C CG  . ASP B 1 375 ? -15.064 -46.985 -9.439  1.00 74.77  ? 375 ASP B CG  1 
ATOM   6590  O OD1 . ASP B 1 375 ? -14.218 -46.331 -8.810  1.00 72.72  ? 375 ASP B OD1 1 
ATOM   6591  O OD2 . ASP B 1 375 ? -15.052 -47.091 -10.686 1.00 77.00  ? 375 ASP B OD2 1 
ATOM   6592  N N   . ALA B 1 376 ? -16.753 -50.510 -6.601  1.00 55.75  ? 376 ALA B N   1 
ATOM   6593  C CA  . ALA B 1 376 ? -17.712 -51.238 -5.772  1.00 54.56  ? 376 ALA B CA  1 
ATOM   6594  C C   . ALA B 1 376 ? -17.316 -51.124 -4.302  1.00 45.36  ? 376 ALA B C   1 
ATOM   6595  O O   . ALA B 1 376 ? -18.163 -51.215 -3.422  1.00 48.42  ? 376 ALA B O   1 
ATOM   6596  C CB  . ALA B 1 376 ? -17.816 -52.702 -6.207  1.00 46.56  ? 376 ALA B CB  1 
ATOM   6597  N N   . HIS B 1 377 ? -16.018 -50.939 -4.040  1.00 46.55  ? 377 HIS B N   1 
ATOM   6598  C CA  . HIS B 1 377 ? -15.486 -51.202 -2.714  1.00 54.85  ? 377 HIS B CA  1 
ATOM   6599  C C   . HIS B 1 377 ? -15.034 -49.917 -2.019  1.00 51.59  ? 377 HIS B C   1 
ATOM   6600  O O   . HIS B 1 377 ? -14.973 -49.885 -0.792  1.00 47.03  ? 377 HIS B O   1 
ATOM   6601  C CB  . HIS B 1 377 ? -14.402 -52.290 -2.760  1.00 53.45  ? 377 HIS B CB  1 
ATOM   6602  C CG  . HIS B 1 377 ? -14.410 -53.188 -1.559  1.00 53.92  ? 377 HIS B CG  1 
ATOM   6603  N ND1 . HIS B 1 377 ? -14.555 -52.716 -0.272  1.00 52.56  ? 377 HIS B ND1 1 
ATOM   6604  C CD2 . HIS B 1 377 ? -14.315 -54.524 -1.457  1.00 51.24  ? 377 HIS B CD2 1 
ATOM   6605  C CE1 . HIS B 1 377 ? -14.542 -53.746 0.568   1.00 59.72  ? 377 HIS B CE1 1 
ATOM   6606  N NE2 . HIS B 1 377 ? -14.384 -54.856 -0.130  1.00 53.41  ? 377 HIS B NE2 1 
ATOM   6607  N N   . SER B 1 378 ? -14.741 -48.872 -2.795  1.00 47.35  ? 378 SER B N   1 
ATOM   6608  C CA  . SER B 1 378 ? -14.023 -47.709 -2.289  1.00 53.24  ? 378 SER B CA  1 
ATOM   6609  C C   . SER B 1 378 ? -14.906 -46.838 -1.384  1.00 53.94  ? 378 SER B C   1 
ATOM   6610  O O   . SER B 1 378 ? -14.446 -46.391 -0.331  1.00 50.12  ? 378 SER B O   1 
ATOM   6611  C CB  . SER B 1 378 ? -13.404 -46.910 -3.429  1.00 48.52  ? 378 SER B CB  1 
ATOM   6612  O OG  . SER B 1 378 ? -14.408 -46.384 -4.279  1.00 54.30  ? 378 SER B OG  1 
ATOM   6613  N N   . GLY B 1 379 ? -16.159 -46.600 -1.775  1.00 50.98  ? 379 GLY B N   1 
ATOM   6614  C CA  . GLY B 1 379 ? -17.018 -45.680 -1.038  1.00 51.94  ? 379 GLY B CA  1 
ATOM   6615  C C   . GLY B 1 379 ? -17.255 -46.083 0.423   1.00 55.30  ? 379 GLY B C   1 
ATOM   6616  O O   . GLY B 1 379 ? -17.301 -45.231 1.310   1.00 50.42  ? 379 GLY B O   1 
ATOM   6617  N N   . VAL B 1 380 ? -17.425 -47.377 0.703   1.00 54.19  ? 380 VAL B N   1 
ATOM   6618  C CA  . VAL B 1 380 ? -17.701 -47.796 2.073   1.00 54.07  ? 380 VAL B CA  1 
ATOM   6619  C C   . VAL B 1 380 ? -16.453 -47.653 2.941   1.00 48.64  ? 380 VAL B C   1 
ATOM   6620  O O   . VAL B 1 380 ? -16.580 -47.498 4.142   1.00 53.38  ? 380 VAL B O   1 
ATOM   6621  C CB  . VAL B 1 380 ? -18.245 -49.242 2.154   1.00 56.62  ? 380 VAL B CB  1 
ATOM   6622  C CG1 . VAL B 1 380 ? -19.645 -49.334 1.576   1.00 57.59  ? 380 VAL B CG1 1 
ATOM   6623  C CG2 . VAL B 1 380 ? -17.318 -50.258 1.496   1.00 51.85  ? 380 VAL B CG2 1 
ATOM   6624  N N   . LEU B 1 381 ? -15.252 -47.791 2.361   1.00 48.84  ? 381 LEU B N   1 
ATOM   6625  C CA  . LEU B 1 381 ? -14.038 -47.634 3.140   1.00 54.22  ? 381 LEU B CA  1 
ATOM   6626  C C   . LEU B 1 381 ? -13.893 -46.192 3.633   1.00 59.27  ? 381 LEU B C   1 
ATOM   6627  O O   . LEU B 1 381 ? -13.479 -45.976 4.786   1.00 45.65  ? 381 LEU B O   1 
ATOM   6628  C CB  . LEU B 1 381 ? -12.830 -48.048 2.297   1.00 59.06  ? 381 LEU B CB  1 
ATOM   6629  C CG  . LEU B 1 381 ? -12.805 -49.500 1.825   1.00 61.20  ? 381 LEU B CG  1 
ATOM   6630  C CD1 . LEU B 1 381 ? -11.561 -49.759 0.966   1.00 59.63  ? 381 LEU B CD1 1 
ATOM   6631  C CD2 . LEU B 1 381 ? -12.867 -50.459 3.001   1.00 57.64  ? 381 LEU B CD2 1 
ATOM   6632  N N   . LEU B 1 382 ? -14.205 -45.226 2.738   1.00 50.44  ? 382 LEU B N   1 
ATOM   6633  C CA  . LEU B 1 382 ? -14.144 -43.808 3.058   1.00 47.47  ? 382 LEU B CA  1 
ATOM   6634  C C   . LEU B 1 382 ? -15.200 -43.456 4.100   1.00 45.81  ? 382 LEU B C   1 
ATOM   6635  O O   . LEU B 1 382 ? -14.867 -42.810 5.097   1.00 42.99  ? 382 LEU B O   1 
ATOM   6636  C CB  . LEU B 1 382 ? -14.313 -42.971 1.792   1.00 43.08  ? 382 LEU B CB  1 
ATOM   6637  C CG  . LEU B 1 382 ? -13.240 -43.210 0.741   1.00 48.37  ? 382 LEU B CG  1 
ATOM   6638  C CD1 . LEU B 1 382 ? -13.547 -42.432 -0.520  1.00 45.25  ? 382 LEU B CD1 1 
ATOM   6639  C CD2 . LEU B 1 382 ? -11.849 -42.891 1.272   1.00 53.99  ? 382 LEU B CD2 1 
ATOM   6640  N N   . TRP B 1 383 ? -16.448 -43.890 3.879   1.00 45.09  ? 383 TRP B N   1 
ATOM   6641  C CA  . TRP B 1 383 ? -17.549 -43.552 4.774   1.00 49.05  ? 383 TRP B CA  1 
ATOM   6642  C C   . TRP B 1 383 ? -17.300 -44.116 6.182   1.00 56.77  ? 383 TRP B C   1 
ATOM   6643  O O   . TRP B 1 383 ? -17.659 -43.483 7.168   1.00 58.84  ? 383 TRP B O   1 
ATOM   6644  C CB  . TRP B 1 383 ? -18.872 -44.047 4.188   1.00 49.80  ? 383 TRP B CB  1 
ATOM   6645  C CG  . TRP B 1 383 ? -20.105 -43.672 4.953   1.00 51.00  ? 383 TRP B CG  1 
ATOM   6646  C CD1 . TRP B 1 383 ? -20.608 -44.328 6.040   1.00 54.81  ? 383 TRP B CD1 1 
ATOM   6647  C CD2 . TRP B 1 383 ? -21.023 -42.596 4.682   1.00 44.17  ? 383 TRP B CD2 1 
ATOM   6648  N NE1 . TRP B 1 383 ? -21.768 -43.734 6.464   1.00 53.75  ? 383 TRP B NE1 1 
ATOM   6649  C CE2 . TRP B 1 383 ? -22.048 -42.670 5.656   1.00 47.31  ? 383 TRP B CE2 1 
ATOM   6650  C CE3 . TRP B 1 383 ? -21.085 -41.569 3.728   1.00 48.22  ? 383 TRP B CE3 1 
ATOM   6651  C CZ2 . TRP B 1 383 ? -23.103 -41.757 5.713   1.00 46.29  ? 383 TRP B CZ2 1 
ATOM   6652  C CZ3 . TRP B 1 383 ? -22.128 -40.663 3.776   1.00 44.28  ? 383 TRP B CZ3 1 
ATOM   6653  C CH2 . TRP B 1 383 ? -23.128 -40.763 4.751   1.00 53.00  ? 383 TRP B CH2 1 
ATOM   6654  N N   . HIS B 1 384 ? -16.652 -45.284 6.290   1.00 51.34  ? 384 HIS B N   1 
ATOM   6655  C CA  . HIS B 1 384 ? -16.470 -45.904 7.596   1.00 58.13  ? 384 HIS B CA  1 
ATOM   6656  C C   . HIS B 1 384 ? -15.622 -44.979 8.481   1.00 53.30  ? 384 HIS B C   1 
ATOM   6657  O O   . HIS B 1 384 ? -15.976 -44.664 9.611   1.00 52.17  ? 384 HIS B O   1 
ATOM   6658  C CB  . HIS B 1 384 ? -15.862 -47.308 7.446   1.00 57.28  ? 384 HIS B CB  1 
ATOM   6659  C CG  . HIS B 1 384 ? -15.397 -47.911 8.735   1.00 55.66  ? 384 HIS B CG  1 
ATOM   6660  N ND1 . HIS B 1 384 ? -16.279 -48.390 9.685   1.00 51.67  ? 384 HIS B ND1 1 
ATOM   6661  C CD2 . HIS B 1 384 ? -14.147 -48.089 9.245   1.00 56.55  ? 384 HIS B CD2 1 
ATOM   6662  C CE1 . HIS B 1 384 ? -15.581 -48.852 10.725  1.00 56.19  ? 384 HIS B CE1 1 
ATOM   6663  N NE2 . HIS B 1 384 ? -14.285 -48.690 10.475  1.00 48.83  ? 384 HIS B NE2 1 
ATOM   6664  N N   . TYR B 1 385 ? -14.504 -44.511 7.938   1.00 44.98  ? 385 TYR B N   1 
ATOM   6665  C CA  . TYR B 1 385 ? -13.574 -43.712 8.703   1.00 52.37  ? 385 TYR B CA  1 
ATOM   6666  C C   . TYR B 1 385 ? -14.025 -42.248 8.831   1.00 51.37  ? 385 TYR B C   1 
ATOM   6667  O O   . TYR B 1 385 ? -13.250 -41.416 9.285   1.00 56.60  ? 385 TYR B O   1 
ATOM   6668  C CB  . TYR B 1 385 ? -12.197 -43.829 8.047   1.00 54.77  ? 385 TYR B CB  1 
ATOM   6669  C CG  . TYR B 1 385 ? -11.547 -45.169 8.229   1.00 59.67  ? 385 TYR B CG  1 
ATOM   6670  C CD1 . TYR B 1 385 ? -11.087 -45.562 9.478   1.00 63.09  ? 385 TYR B CD1 1 
ATOM   6671  C CD2 . TYR B 1 385 ? -11.415 -46.057 7.176   1.00 56.89  ? 385 TYR B CD2 1 
ATOM   6672  C CE1 . TYR B 1 385 ? -10.480 -46.788 9.672   1.00 60.22  ? 385 TYR B CE1 1 
ATOM   6673  C CE2 . TYR B 1 385 ? -10.826 -47.295 7.356   1.00 60.64  ? 385 TYR B CE2 1 
ATOM   6674  C CZ  . TYR B 1 385 ? -10.356 -47.661 8.610   1.00 63.55  ? 385 TYR B CZ  1 
ATOM   6675  O OH  . TYR B 1 385 ? -9.764  -48.872 8.826   1.00 59.82  ? 385 TYR B OH  1 
ATOM   6676  N N   . GLY B 1 386 ? -15.256 -41.922 8.418   1.00 53.21  ? 386 GLY B N   1 
ATOM   6677  C CA  . GLY B 1 386 ? -15.814 -40.586 8.586   1.00 53.03  ? 386 GLY B CA  1 
ATOM   6678  C C   . GLY B 1 386 ? -15.631 -39.605 7.411   1.00 50.54  ? 386 GLY B C   1 
ATOM   6679  O O   . GLY B 1 386 ? -15.956 -38.449 7.594   1.00 49.40  ? 386 GLY B O   1 
ATOM   6680  N N   . ILE B 1 387 ? -15.105 -39.999 6.236   1.00 47.37  ? 387 ILE B N   1 
ATOM   6681  C CA  . ILE B 1 387 ? -15.152 -39.128 5.068   1.00 45.23  ? 387 ILE B CA  1 
ATOM   6682  C C   . ILE B 1 387 ? -16.496 -39.322 4.358   1.00 44.28  ? 387 ILE B C   1 
ATOM   6683  O O   . ILE B 1 387 ? -16.630 -40.238 3.564   1.00 41.21  ? 387 ILE B O   1 
ATOM   6684  C CB  . ILE B 1 387 ? -13.959 -39.367 4.116   1.00 48.93  ? 387 ILE B CB  1 
ATOM   6685  C CG1 . ILE B 1 387 ? -12.611 -39.184 4.824   1.00 55.63  ? 387 ILE B CG1 1 
ATOM   6686  C CG2 . ILE B 1 387 ? -14.052 -38.465 2.880   1.00 45.15  ? 387 ILE B CG2 1 
ATOM   6687  C CD1 . ILE B 1 387 ? -11.853 -40.463 5.066   1.00 61.60  ? 387 ILE B CD1 1 
ATOM   6688  N N   . ARG B 1 388 ? -17.474 -38.442 4.619   1.00 48.78  ? 388 ARG B N   1 
ATOM   6689  C CA  . ARG B 1 388 ? -18.874 -38.638 4.239   1.00 54.40  ? 388 ARG B CA  1 
ATOM   6690  C C   . ARG B 1 388 ? -19.381 -37.668 3.168   1.00 46.85  ? 388 ARG B C   1 
ATOM   6691  O O   . ARG B 1 388 ? -20.572 -37.672 2.832   1.00 43.71  ? 388 ARG B O   1 
ATOM   6692  C CB  . ARG B 1 388 ? -19.791 -38.423 5.445   1.00 55.56  ? 388 ARG B CB  1 
ATOM   6693  C CG  . ARG B 1 388 ? -19.375 -39.285 6.615   1.00 62.10  ? 388 ARG B CG  1 
ATOM   6694  C CD  . ARG B 1 388 ? -20.489 -39.672 7.563   1.00 66.22  ? 388 ARG B CD  1 
ATOM   6695  N NE  . ARG B 1 388 ? -19.904 -40.833 8.232   1.00 84.55  ? 388 ARG B NE  1 
ATOM   6696  C CZ  . ARG B 1 388 ? -20.574 -41.755 8.896   1.00 76.20  ? 388 ARG B CZ  1 
ATOM   6697  N NH1 . ARG B 1 388 ? -21.840 -41.540 9.236   1.00 68.82  ? 388 ARG B NH1 1 
ATOM   6698  N NH2 . ARG B 1 388 ? -19.945 -42.873 9.217   1.00 70.47  ? 388 ARG B NH2 1 
ATOM   6699  N N   . GLU B 1 389 ? -18.475 -36.855 2.639   1.00 45.84  ? 389 GLU B N   1 
ATOM   6700  C CA  . GLU B 1 389 ? -18.810 -35.797 1.707   1.00 44.30  ? 389 GLU B CA  1 
ATOM   6701  C C   . GLU B 1 389 ? -18.658 -36.324 0.287   1.00 47.30  ? 389 GLU B C   1 
ATOM   6702  O O   . GLU B 1 389 ? -17.566 -36.291 -0.288  1.00 50.47  ? 389 GLU B O   1 
ATOM   6703  C CB  . GLU B 1 389 ? -17.899 -34.622 2.047   1.00 51.95  ? 389 GLU B CB  1 
ATOM   6704  C CG  . GLU B 1 389 ? -18.151 -34.079 3.468   1.00 57.14  ? 389 GLU B CG  1 
ATOM   6705  C CD  . GLU B 1 389 ? -17.422 -34.714 4.655   1.00 55.29  ? 389 GLU B CD  1 
ATOM   6706  O OE1 . GLU B 1 389 ? -17.792 -34.373 5.818   1.00 55.85  ? 389 GLU B OE1 1 
ATOM   6707  O OE2 . GLU B 1 389 ? -16.438 -35.486 4.434   1.00 47.28  ? 389 GLU B OE2 1 
ATOM   6708  N N   . TYR B 1 390 ? -19.768 -36.843 -0.241  1.00 45.05  ? 390 TYR B N   1 
ATOM   6709  C CA  . TYR B 1 390 ? -19.827 -37.473 -1.557  1.00 51.89  ? 390 TYR B CA  1 
ATOM   6710  C C   . TYR B 1 390 ? -19.065 -36.688 -2.639  1.00 46.80  ? 390 TYR B C   1 
ATOM   6711  O O   . TYR B 1 390 ? -18.162 -37.229 -3.283  1.00 45.64  ? 390 TYR B O   1 
ATOM   6712  C CB  . TYR B 1 390 ? -21.288 -37.634 -1.995  1.00 54.71  ? 390 TYR B CB  1 
ATOM   6713  C CG  . TYR B 1 390 ? -22.120 -38.517 -1.103  1.00 57.22  ? 390 TYR B CG  1 
ATOM   6714  C CD1 . TYR B 1 390 ? -22.054 -39.906 -1.191  1.00 61.79  ? 390 TYR B CD1 1 
ATOM   6715  C CD2 . TYR B 1 390 ? -22.965 -37.962 -0.157  1.00 57.85  ? 390 TYR B CD2 1 
ATOM   6716  C CE1 . TYR B 1 390 ? -22.830 -40.724 -0.379  1.00 59.40  ? 390 TYR B CE1 1 
ATOM   6717  C CE2 . TYR B 1 390 ? -23.727 -38.759 0.685   1.00 58.59  ? 390 TYR B CE2 1 
ATOM   6718  C CZ  . TYR B 1 390 ? -23.657 -40.143 0.575   1.00 58.68  ? 390 TYR B CZ  1 
ATOM   6719  O OH  . TYR B 1 390 ? -24.432 -40.911 1.405   1.00 52.14  ? 390 TYR B OH  1 
ATOM   6720  N N   . ASP B 1 391 ? -19.408 -35.412 -2.820  1.00 45.40  ? 391 ASP B N   1 
ATOM   6721  C CA  . ASP B 1 391 ? -18.834 -34.606 -3.893  1.00 48.74  ? 391 ASP B CA  1 
ATOM   6722  C C   . ASP B 1 391 ? -17.297 -34.639 -3.890  1.00 46.15  ? 391 ASP B C   1 
ATOM   6723  O O   . ASP B 1 391 ? -16.676 -34.693 -4.966  1.00 45.64  ? 391 ASP B O   1 
ATOM   6724  C CB  . ASP B 1 391 ? -19.402 -33.190 -3.831  1.00 57.87  ? 391 ASP B CB  1 
ATOM   6725  C CG  . ASP B 1 391 ? -20.849 -33.136 -4.277  1.00 60.74  ? 391 ASP B CG  1 
ATOM   6726  O OD1 . ASP B 1 391 ? -21.280 -34.129 -4.881  1.00 70.45  ? 391 ASP B OD1 1 
ATOM   6727  O OD2 . ASP B 1 391 ? -21.539 -32.118 -4.002  1.00 68.20  ? 391 ASP B OD2 1 
ATOM   6728  N N   . PHE B 1 392 ? -16.704 -34.735 -2.688  1.00 40.04  ? 392 PHE B N   1 
ATOM   6729  C CA  . PHE B 1 392 ? -15.260 -34.723 -2.503  1.00 35.52  ? 392 PHE B CA  1 
ATOM   6730  C C   . PHE B 1 392 ? -14.611 -36.051 -2.896  1.00 38.39  ? 392 PHE B C   1 
ATOM   6731  O O   . PHE B 1 392 ? -13.387 -36.103 -3.069  1.00 41.08  ? 392 PHE B O   1 
ATOM   6732  C CB  . PHE B 1 392 ? -14.914 -34.344 -1.056  1.00 36.67  ? 392 PHE B CB  1 
ATOM   6733  C CG  . PHE B 1 392 ? -13.452 -34.043 -0.843  1.00 37.98  ? 392 PHE B CG  1 
ATOM   6734  C CD1 . PHE B 1 392 ? -12.913 -32.830 -1.243  1.00 37.89  ? 392 PHE B CD1 1 
ATOM   6735  C CD2 . PHE B 1 392 ? -12.608 -34.984 -0.276  1.00 39.23  ? 392 PHE B CD2 1 
ATOM   6736  C CE1 . PHE B 1 392 ? -11.571 -32.547 -1.045  1.00 41.67  ? 392 PHE B CE1 1 
ATOM   6737  C CE2 . PHE B 1 392 ? -11.256 -34.715 -0.108  1.00 41.22  ? 392 PHE B CE2 1 
ATOM   6738  C CZ  . PHE B 1 392 ? -10.746 -33.491 -0.478  1.00 42.37  ? 392 PHE B CZ  1 
ATOM   6739  N N   . TYR B 1 393 ? -15.400 -37.119 -3.089  1.00 43.02  ? 393 TYR B N   1 
ATOM   6740  C CA  . TYR B 1 393 ? -14.808 -38.416 -3.445  1.00 39.57  ? 393 TYR B CA  1 
ATOM   6741  C C   . TYR B 1 393 ? -14.020 -38.293 -4.740  1.00 36.57  ? 393 TYR B C   1 
ATOM   6742  O O   . TYR B 1 393 ? -12.934 -38.850 -4.864  1.00 39.91  ? 393 TYR B O   1 
ATOM   6743  C CB  . TYR B 1 393 ? -15.849 -39.537 -3.507  1.00 35.92  ? 393 TYR B CB  1 
ATOM   6744  C CG  . TYR B 1 393 ? -16.397 -40.004 -2.170  1.00 44.61  ? 393 TYR B CG  1 
ATOM   6745  C CD1 . TYR B 1 393 ? -16.227 -39.289 -1.001  1.00 43.31  ? 393 TYR B CD1 1 
ATOM   6746  C CD2 . TYR B 1 393 ? -17.087 -41.202 -2.071  1.00 47.05  ? 393 TYR B CD2 1 
ATOM   6747  C CE1 . TYR B 1 393 ? -16.726 -39.733 0.216   1.00 45.50  ? 393 TYR B CE1 1 
ATOM   6748  C CE2 . TYR B 1 393 ? -17.591 -41.664 -0.868  1.00 48.08  ? 393 TYR B CE2 1 
ATOM   6749  C CZ  . TYR B 1 393 ? -17.389 -40.941 0.291   1.00 50.94  ? 393 TYR B CZ  1 
ATOM   6750  O OH  . TYR B 1 393 ? -17.914 -41.391 1.477   1.00 43.87  ? 393 TYR B OH  1 
ATOM   6751  N N   . THR B 1 394 ? -14.551 -37.530 -5.697  1.00 35.29  ? 394 THR B N   1 
ATOM   6752  C CA  . THR B 1 394 ? -13.883 -37.389 -6.976  1.00 34.23  ? 394 THR B CA  1 
ATOM   6753  C C   . THR B 1 394 ? -12.536 -36.702 -6.802  1.00 33.84  ? 394 THR B C   1 
ATOM   6754  O O   . THR B 1 394 ? -11.604 -36.944 -7.583  1.00 35.38  ? 394 THR B O   1 
ATOM   6755  C CB  . THR B 1 394 ? -14.781 -36.672 -7.989  1.00 34.44  ? 394 THR B CB  1 
ATOM   6756  O OG1 . THR B 1 394 ? -16.037 -37.324 -7.968  1.00 33.99  ? 394 THR B OG1 1 
ATOM   6757  C CG2 . THR B 1 394 ? -14.272 -36.775 -9.410  1.00 40.02  ? 394 THR B CG2 1 
ATOM   6758  N N   . VAL B 1 395 ? -12.386 -35.898 -5.743  1.00 35.94  ? 395 VAL B N   1 
ATOM   6759  C CA  . VAL B 1 395 ? -11.124 -35.182 -5.562  1.00 38.01  ? 395 VAL B CA  1 
ATOM   6760  C C   . VAL B 1 395 ? -10.031 -36.165 -5.138  1.00 36.27  ? 395 VAL B C   1 
ATOM   6761  O O   . VAL B 1 395 ? -8.904  -36.112 -5.649  1.00 32.53  ? 395 VAL B O   1 
ATOM   6762  C CB  . VAL B 1 395 ? -11.254 -33.990 -4.580  1.00 37.16  ? 395 VAL B CB  1 
ATOM   6763  C CG1 . VAL B 1 395 ? -9.901  -33.398 -4.213  1.00 34.42  ? 395 VAL B CG1 1 
ATOM   6764  C CG2 . VAL B 1 395 ? -12.176 -32.919 -5.125  1.00 33.75  ? 395 VAL B CG2 1 
ATOM   6765  N N   . LEU B 1 396 ? -10.364 -37.056 -4.194  1.00 37.15  ? 396 LEU B N   1 
ATOM   6766  C CA  . LEU B 1 396 ? -9.478  -38.150 -3.804  1.00 38.07  ? 396 LEU B CA  1 
ATOM   6767  C C   . LEU B 1 396 ? -9.071  -38.967 -5.037  1.00 36.18  ? 396 LEU B C   1 
ATOM   6768  O O   . LEU B 1 396 ? -7.887  -39.240 -5.292  1.00 36.81  ? 396 LEU B O   1 
ATOM   6769  C CB  . LEU B 1 396 ? -10.176 -39.026 -2.753  1.00 41.35  ? 396 LEU B CB  1 
ATOM   6770  C CG  . LEU B 1 396 ? -10.551 -38.324 -1.443  1.00 40.47  ? 396 LEU B CG  1 
ATOM   6771  C CD1 . LEU B 1 396 ? -11.265 -39.276 -0.504  1.00 47.50  ? 396 LEU B CD1 1 
ATOM   6772  C CD2 . LEU B 1 396 ? -9.326  -37.761 -0.729  1.00 42.04  ? 396 LEU B CD2 1 
ATOM   6773  N N   . PHE B 1 397 ? -10.048 -39.303 -5.861  1.00 35.73  ? 397 PHE B N   1 
ATOM   6774  C CA  . PHE B 1 397 ? -9.757  -40.031 -7.083  1.00 36.00  ? 397 PHE B CA  1 
ATOM   6775  C C   . PHE B 1 397 ? -8.723  -39.266 -7.900  1.00 39.63  ? 397 PHE B C   1 
ATOM   6776  O O   . PHE B 1 397 ? -7.800  -39.862 -8.470  1.00 38.08  ? 397 PHE B O   1 
ATOM   6777  C CB  . PHE B 1 397 ? -11.072 -40.227 -7.859  1.00 39.31  ? 397 PHE B CB  1 
ATOM   6778  C CG  . PHE B 1 397 ? -11.068 -41.186 -9.028  1.00 40.22  ? 397 PHE B CG  1 
ATOM   6779  C CD1 . PHE B 1 397 ? -9.948  -41.903 -9.394  1.00 43.91  ? 397 PHE B CD1 1 
ATOM   6780  C CD2 . PHE B 1 397 ? -12.222 -41.373 -9.779  1.00 59.27  ? 397 PHE B CD2 1 
ATOM   6781  C CE1 . PHE B 1 397 ? -9.964  -42.754 -10.501 1.00 57.80  ? 397 PHE B CE1 1 
ATOM   6782  C CE2 . PHE B 1 397 ? -12.252 -42.239 -10.871 1.00 57.00  ? 397 PHE B CE2 1 
ATOM   6783  C CZ  . PHE B 1 397 ? -11.116 -42.929 -11.236 1.00 52.51  ? 397 PHE B CZ  1 
ATOM   6784  N N   . GLY B 1 398 ? -8.950  -37.937 -7.987  1.00 39.44  ? 398 GLY B N   1 
ATOM   6785  C CA  . GLY B 1 398 ? -8.123  -37.031 -8.761  1.00 31.90  ? 398 GLY B CA  1 
ATOM   6786  C C   . GLY B 1 398 ? -6.683  -36.989 -8.269  1.00 33.46  ? 398 GLY B C   1 
ATOM   6787  O O   . GLY B 1 398 ? -5.738  -37.042 -9.062  1.00 35.66  ? 398 GLY B O   1 
ATOM   6788  N N   . VAL B 1 399 ? -6.516  -36.885 -6.949  1.00 37.13  ? 399 VAL B N   1 
ATOM   6789  C CA  . VAL B 1 399 ? -5.187  -36.900 -6.349  1.00 34.14  ? 399 VAL B CA  1 
ATOM   6790  C C   . VAL B 1 399 ? -4.496  -38.212 -6.727  1.00 36.64  ? 399 VAL B C   1 
ATOM   6791  O O   . VAL B 1 399 ? -3.342  -38.224 -7.128  1.00 35.41  ? 399 VAL B O   1 
ATOM   6792  C CB  . VAL B 1 399 ? -5.305  -36.715 -4.822  1.00 36.76  ? 399 VAL B CB  1 
ATOM   6793  C CG1 . VAL B 1 399 ? -4.020  -37.001 -4.083  1.00 37.08  ? 399 VAL B CG1 1 
ATOM   6794  C CG2 . VAL B 1 399 ? -5.804  -35.312 -4.454  1.00 37.92  ? 399 VAL B CG2 1 
ATOM   6795  N N   . SER B 1 400 ? -5.193  -39.347 -6.605  1.00 36.65  ? 400 SER B N   1 
ATOM   6796  C CA  . SER B 1 400 ? -4.574  -40.610 -7.010  1.00 38.28  ? 400 SER B CA  1 
ATOM   6797  C C   . SER B 1 400 ? -4.159  -40.588 -8.480  1.00 35.77  ? 400 SER B C   1 
ATOM   6798  O O   . SER B 1 400 ? -3.010  -40.864 -8.843  1.00 31.95  ? 400 SER B O   1 
ATOM   6799  C CB  . SER B 1 400 ? -5.486  -41.770 -6.771  1.00 39.96  ? 400 SER B CB  1 
ATOM   6800  O OG  . SER B 1 400 ? -4.849  -43.001 -7.079  1.00 37.76  ? 400 SER B OG  1 
ATOM   6801  N N   . ARG B 1 401 ? -5.127  -40.266 -9.343  1.00 36.49  ? 401 ARG B N   1 
ATOM   6802  C CA  . ARG B 1 401 ? -4.920  -40.415 -10.775 1.00 37.45  ? 401 ARG B CA  1 
ATOM   6803  C C   . ARG B 1 401 ? -3.779  -39.533 -11.284 1.00 39.42  ? 401 ARG B C   1 
ATOM   6804  O O   . ARG B 1 401 ? -3.282  -39.731 -12.390 1.00 35.92  ? 401 ARG B O   1 
ATOM   6805  C CB  . ARG B 1 401 ? -6.260  -40.123 -11.443 1.00 40.68  ? 401 ARG B CB  1 
ATOM   6806  C CG  . ARG B 1 401 ? -6.378  -40.605 -12.868 1.00 45.52  ? 401 ARG B CG  1 
ATOM   6807  C CD  . ARG B 1 401 ? -5.832  -41.978 -13.192 1.00 46.44  ? 401 ARG B CD  1 
ATOM   6808  N NE  . ARG B 1 401 ? -6.568  -43.057 -12.564 1.00 52.61  ? 401 ARG B NE  1 
ATOM   6809  C CZ  . ARG B 1 401 ? -7.546  -43.755 -13.131 1.00 46.66  ? 401 ARG B CZ  1 
ATOM   6810  N NH1 . ARG B 1 401 ? -8.168  -43.304 -14.210 1.00 46.97  ? 401 ARG B NH1 1 
ATOM   6811  N NH2 . ARG B 1 401 ? -7.962  -44.857 -12.540 1.00 41.84  ? 401 ARG B NH2 1 
ATOM   6812  N N   . ALA B 1 402 ? -3.331  -38.549 -10.478 1.00 39.50  ? 402 ALA B N   1 
ATOM   6813  C CA  . ALA B 1 402 ? -2.236  -37.673 -10.888 1.00 35.28  ? 402 ALA B CA  1 
ATOM   6814  C C   . ALA B 1 402 ? -0.922  -38.427 -11.019 1.00 35.29  ? 402 ALA B C   1 
ATOM   6815  O O   . ALA B 1 402 ? 0.005   -37.986 -11.719 1.00 31.49  ? 402 ALA B O   1 
ATOM   6816  C CB  . ALA B 1 402 ? -2.093  -36.543 -9.891  1.00 40.20  ? 402 ALA B CB  1 
ATOM   6817  N N   . LEU B 1 403 ? -0.814  -39.527 -10.263 1.00 39.28  ? 403 LEU B N   1 
ATOM   6818  C CA  . LEU B 1 403 ? 0.398   -40.330 -10.290 1.00 39.98  ? 403 LEU B CA  1 
ATOM   6819  C C   . LEU B 1 403 ? 0.590   -40.866 -11.705 1.00 38.39  ? 403 LEU B C   1 
ATOM   6820  O O   . LEU B 1 403 ? 1.646   -40.669 -12.324 1.00 43.51  ? 403 LEU B O   1 
ATOM   6821  C CB  . LEU B 1 403 ? 0.238   -41.470 -9.284  1.00 41.07  ? 403 LEU B CB  1 
ATOM   6822  C CG  . LEU B 1 403 ? 0.275   -41.056 -7.819  1.00 41.33  ? 403 LEU B CG  1 
ATOM   6823  C CD1 . LEU B 1 403 ? -0.191  -42.184 -6.940  1.00 46.55  ? 403 LEU B CD1 1 
ATOM   6824  C CD2 . LEU B 1 403 ? 1.675   -40.638 -7.409  1.00 43.91  ? 403 LEU B CD2 1 
ATOM   6825  N N   . GLY B 1 404 ? -0.461  -41.508 -12.213 1.00 36.79  ? 404 GLY B N   1 
ATOM   6826  C CA  . GLY B 1 404 ? -0.470  -42.041 -13.566 1.00 38.01  ? 404 GLY B CA  1 
ATOM   6827  C C   . GLY B 1 404 ? -0.380  -40.938 -14.618 1.00 42.40  ? 404 GLY B C   1 
ATOM   6828  O O   . GLY B 1 404 ? 0.420   -41.048 -15.552 1.00 39.27  ? 404 GLY B O   1 
ATOM   6829  N N   . CYS B 1 405 ? -1.131  -39.835 -14.436 1.00 41.07  ? 405 CYS B N   1 
ATOM   6830  C CA  . CYS B 1 405 ? -1.160  -38.821 -15.489 1.00 37.65  ? 405 CYS B CA  1 
ATOM   6831  C C   . CYS B 1 405 ? 0.203   -38.167 -15.617 1.00 35.01  ? 405 CYS B C   1 
ATOM   6832  O O   . CYS B 1 405 ? 0.636   -37.847 -16.718 1.00 33.80  ? 405 CYS B O   1 
ATOM   6833  C CB  . CYS B 1 405 ? -2.240  -37.771 -15.279 1.00 41.84  ? 405 CYS B CB  1 
ATOM   6834  S SG  . CYS B 1 405 ? -3.942  -38.360 -15.496 1.00 49.13  ? 405 CYS B SG  1 
ATOM   6835  N N   . THR B 1 406 ? 0.897   -37.985 -14.486 1.00 37.20  ? 406 THR B N   1 
ATOM   6836  C CA  . THR B 1 406 ? 2.218   -37.379 -14.532 1.00 33.17  ? 406 THR B CA  1 
ATOM   6837  C C   . THR B 1 406 ? 3.239   -38.339 -15.117 1.00 30.88  ? 406 THR B C   1 
ATOM   6838  O O   . THR B 1 406 ? 4.090   -37.933 -15.905 1.00 36.34  ? 406 THR B O   1 
ATOM   6839  C CB  . THR B 1 406 ? 2.719   -36.926 -13.163 1.00 36.46  ? 406 THR B CB  1 
ATOM   6840  O OG1 . THR B 1 406 ? 2.615   -37.994 -12.224 1.00 33.92  ? 406 THR B OG1 1 
ATOM   6841  C CG2 . THR B 1 406 ? 1.986   -35.701 -12.664 1.00 37.47  ? 406 THR B CG2 1 
ATOM   6842  N N   . ALA B 1 407 ? 3.183   -39.603 -14.703 1.00 36.45  ? 407 ALA B N   1 
ATOM   6843  C CA  . ALA B 1 407 ? 4.041   -40.623 -15.276 1.00 38.21  ? 407 ALA B CA  1 
ATOM   6844  C C   . ALA B 1 407 ? 3.947   -40.588 -16.803 1.00 35.66  ? 407 ALA B C   1 
ATOM   6845  O O   . ALA B 1 407 ? 4.956   -40.461 -17.515 1.00 36.78  ? 407 ALA B O   1 
ATOM   6846  C CB  . ALA B 1 407 ? 3.632   -41.959 -14.716 1.00 45.47  ? 407 ALA B CB  1 
ATOM   6847  N N   . GLN B 1 408 ? 2.711   -40.628 -17.291 1.00 36.29  ? 408 GLN B N   1 
ATOM   6848  C CA  . GLN B 1 408 ? 2.443   -40.752 -18.712 1.00 40.57  ? 408 GLN B CA  1 
ATOM   6849  C C   . GLN B 1 408 ? 2.934   -39.528 -19.483 1.00 47.47  ? 408 GLN B C   1 
ATOM   6850  O O   . GLN B 1 408 ? 3.448   -39.654 -20.600 1.00 45.29  ? 408 GLN B O   1 
ATOM   6851  C CB  . GLN B 1 408 ? 0.948   -40.948 -18.936 1.00 45.58  ? 408 GLN B CB  1 
ATOM   6852  C CG  . GLN B 1 408 ? 0.405   -42.310 -18.532 1.00 44.38  ? 408 GLN B CG  1 
ATOM   6853  C CD  . GLN B 1 408 ? -1.062  -42.490 -18.886 1.00 52.73  ? 408 GLN B CD  1 
ATOM   6854  O OE1 . GLN B 1 408 ? -1.846  -43.113 -18.173 1.00 52.14  ? 408 GLN B OE1 1 
ATOM   6855  N NE2 . GLN B 1 408 ? -1.437  -41.995 -20.051 1.00 55.09  ? 408 GLN B NE2 1 
ATOM   6856  N N   . ALA B 1 409 ? 2.735   -38.338 -18.897 1.00 45.27  ? 409 ALA B N   1 
ATOM   6857  C CA  . ALA B 1 409 ? 3.090   -37.111 -19.576 1.00 40.69  ? 409 ALA B CA  1 
ATOM   6858  C C   . ALA B 1 409 ? 4.613   -36.970 -19.598 1.00 40.40  ? 409 ALA B C   1 
ATOM   6859  O O   . ALA B 1 409 ? 5.197   -36.442 -20.550 1.00 44.36  ? 409 ALA B O   1 
ATOM   6860  C CB  . ALA B 1 409 ? 2.401   -35.941 -18.900 1.00 47.61  ? 409 ALA B CB  1 
ATOM   6861  N N   . ILE B 1 410 ? 5.281   -37.468 -18.566 1.00 40.25  ? 410 ILE B N   1 
ATOM   6862  C CA  . ILE B 1 410 ? 6.745   -37.451 -18.585 1.00 41.76  ? 410 ILE B CA  1 
ATOM   6863  C C   . ILE B 1 410 ? 7.268   -38.388 -19.677 1.00 42.54  ? 410 ILE B C   1 
ATOM   6864  O O   . ILE B 1 410 ? 8.097   -37.976 -20.482 1.00 45.42  ? 410 ILE B O   1 
ATOM   6865  C CB  . ILE B 1 410 ? 7.330   -37.786 -17.208 1.00 37.53  ? 410 ILE B CB  1 
ATOM   6866  C CG1 . ILE B 1 410 ? 6.958   -36.718 -16.168 1.00 39.52  ? 410 ILE B CG1 1 
ATOM   6867  C CG2 . ILE B 1 410 ? 8.835   -37.949 -17.321 1.00 38.22  ? 410 ILE B CG2 1 
ATOM   6868  C CD1 . ILE B 1 410 ? 7.130   -37.148 -14.728 1.00 40.38  ? 410 ILE B CD1 1 
ATOM   6869  N N   . LEU B 1 411 ? 6.727   -39.612 -19.725 1.00 42.23  ? 411 LEU B N   1 
ATOM   6870  C CA  . LEU B 1 411 ? 7.104   -40.616 -20.705 1.00 44.91  ? 411 LEU B CA  1 
ATOM   6871  C C   . LEU B 1 411 ? 6.899   -40.130 -22.145 1.00 45.08  ? 411 LEU B C   1 
ATOM   6872  O O   . LEU B 1 411 ? 7.805   -40.276 -22.961 1.00 48.18  ? 411 LEU B O   1 
ATOM   6873  C CB  . LEU B 1 411 ? 6.314   -41.899 -20.409 1.00 42.85  ? 411 LEU B CB  1 
ATOM   6874  C CG  . LEU B 1 411 ? 6.770   -42.646 -19.158 1.00 42.99  ? 411 LEU B CG  1 
ATOM   6875  C CD1 . LEU B 1 411 ? 5.880   -43.835 -18.859 1.00 48.06  ? 411 LEU B CD1 1 
ATOM   6876  C CD2 . LEU B 1 411 ? 8.194   -43.114 -19.313 1.00 46.26  ? 411 LEU B CD2 1 
ATOM   6877  N N   . VAL B 1 412 ? 5.746   -39.541 -22.477 1.00 45.32  ? 412 VAL B N   1 
ATOM   6878  C CA  . VAL B 1 412 ? 5.444   -39.312 -23.881 1.00 46.24  ? 412 VAL B CA  1 
ATOM   6879  C C   . VAL B 1 412 ? 6.214   -38.092 -24.371 1.00 46.27  ? 412 VAL B C   1 
ATOM   6880  O O   . VAL B 1 412 ? 6.475   -37.960 -25.567 1.00 46.84  ? 412 VAL B O   1 
ATOM   6881  C CB  . VAL B 1 412 ? 3.929   -39.221 -24.211 1.00 49.92  ? 412 VAL B CB  1 
ATOM   6882  C CG1 . VAL B 1 412 ? 3.207   -40.519 -23.913 1.00 53.10  ? 412 VAL B CG1 1 
ATOM   6883  C CG2 . VAL B 1 412 ? 3.211   -38.080 -23.527 1.00 52.81  ? 412 VAL B CG2 1 
ATOM   6884  N N   . ARG B 1 413 ? 6.572   -37.178 -23.470 1.00 44.77  ? 413 ARG B N   1 
ATOM   6885  C CA  . ARG B 1 413 ? 7.455   -36.092 -23.873 1.00 44.38  ? 413 ARG B CA  1 
ATOM   6886  C C   . ARG B 1 413 ? 8.879   -36.617 -23.981 1.00 41.00  ? 413 ARG B C   1 
ATOM   6887  O O   . ARG B 1 413 ? 9.636   -36.119 -24.803 1.00 47.40  ? 413 ARG B O   1 
ATOM   6888  C CB  . ARG B 1 413 ? 7.370   -34.884 -22.938 1.00 47.75  ? 413 ARG B CB  1 
ATOM   6889  C CG  . ARG B 1 413 ? 5.979   -34.257 -22.855 1.00 48.31  ? 413 ARG B CG  1 
ATOM   6890  C CD  . ARG B 1 413 ? 5.651   -33.327 -24.006 1.00 44.03  ? 413 ARG B CD  1 
ATOM   6891  N NE  . ARG B 1 413 ? 6.146   -33.814 -25.293 1.00 47.19  ? 413 ARG B NE  1 
ATOM   6892  C CZ  . ARG B 1 413 ? 5.414   -34.388 -26.247 1.00 43.63  ? 413 ARG B CZ  1 
ATOM   6893  N NH1 . ARG B 1 413 ? 4.181   -34.817 -26.013 1.00 44.11  ? 413 ARG B NH1 1 
ATOM   6894  N NH2 . ARG B 1 413 ? 5.976   -34.643 -27.408 1.00 41.74  ? 413 ARG B NH2 1 
ATOM   6895  N N   . GLY B 1 414 ? 9.218   -37.658 -23.212 1.00 37.51  ? 414 GLY B N   1 
ATOM   6896  C CA  . GLY B 1 414 ? 10.476  -38.346 -23.406 1.00 38.01  ? 414 GLY B CA  1 
ATOM   6897  C C   . GLY B 1 414 ? 10.573  -39.045 -24.767 1.00 46.06  ? 414 GLY B C   1 
ATOM   6898  O O   . GLY B 1 414 ? 11.659  -39.081 -25.356 1.00 48.88  ? 414 GLY B O   1 
ATOM   6899  N N   . TYR B 1 415 ? 9.443   -39.611 -25.234 1.00 44.44  ? 415 TYR B N   1 
ATOM   6900  C CA  . TYR B 1 415 ? 9.342   -40.298 -26.516 1.00 47.66  ? 415 TYR B CA  1 
ATOM   6901  C C   . TYR B 1 415 ? 9.185   -39.338 -27.700 1.00 53.98  ? 415 TYR B C   1 
ATOM   6902  O O   . TYR B 1 415 ? 9.393   -39.715 -28.863 1.00 51.84  ? 415 TYR B O   1 
ATOM   6903  C CB  . TYR B 1 415 ? 8.070   -41.136 -26.626 1.00 45.67  ? 415 TYR B CB  1 
ATOM   6904  C CG  . TYR B 1 415 ? 7.899   -42.281 -25.669 1.00 46.52  ? 415 TYR B CG  1 
ATOM   6905  C CD1 . TYR B 1 415 ? 8.895   -42.687 -24.794 1.00 44.45  ? 415 TYR B CD1 1 
ATOM   6906  C CD2 . TYR B 1 415 ? 6.702   -42.977 -25.674 1.00 43.40  ? 415 TYR B CD2 1 
ATOM   6907  C CE1 . TYR B 1 415 ? 8.674   -43.752 -23.931 1.00 47.16  ? 415 TYR B CE1 1 
ATOM   6908  C CE2 . TYR B 1 415 ? 6.472   -44.040 -24.823 1.00 45.95  ? 415 TYR B CE2 1 
ATOM   6909  C CZ  . TYR B 1 415 ? 7.469   -44.436 -23.956 1.00 46.94  ? 415 TYR B CZ  1 
ATOM   6910  O OH  . TYR B 1 415 ? 7.187   -45.498 -23.136 1.00 45.75  ? 415 TYR B OH  1 
ATOM   6911  N N   . MET B 1 416 ? 8.724   -38.124 -27.400 1.00 48.14  ? 416 MET B N   1 
ATOM   6912  C CA  . MET B 1 416 ? 8.508   -37.085 -28.393 1.00 44.68  ? 416 MET B CA  1 
ATOM   6913  C C   . MET B 1 416 ? 7.373   -37.480 -29.331 1.00 38.17  ? 416 MET B C   1 
ATOM   6914  O O   . MET B 1 416 ? 7.422   -37.160 -30.509 1.00 40.21  ? 416 MET B O   1 
ATOM   6915  C CB  . MET B 1 416 ? 9.782   -36.782 -29.187 1.00 48.17  ? 416 MET B CB  1 
ATOM   6916  C CG  . MET B 1 416 ? 10.918  -36.382 -28.279 1.00 52.68  ? 416 MET B CG  1 
ATOM   6917  S SD  . MET B 1 416 ? 12.422  -35.784 -29.118 1.00 61.25  ? 416 MET B SD  1 
ATOM   6918  C CE  . MET B 1 416 ? 13.396  -35.387 -27.670 1.00 65.47  ? 416 MET B CE  1 
ATOM   6919  N N   . LEU B 1 417 ? 6.307   -38.086 -28.798 1.00 39.36  ? 417 LEU B N   1 
ATOM   6920  C CA  . LEU B 1 417 ? 5.097   -38.261 -29.589 1.00 43.24  ? 417 LEU B CA  1 
ATOM   6921  C C   . LEU B 1 417 ? 4.579   -36.910 -30.090 1.00 44.79  ? 417 LEU B C   1 
ATOM   6922  O O   . LEU B 1 417 ? 4.782   -35.859 -29.496 1.00 43.25  ? 417 LEU B O   1 
ATOM   6923  C CB  . LEU B 1 417 ? 4.036   -38.976 -28.765 1.00 45.88  ? 417 LEU B CB  1 
ATOM   6924  C CG  . LEU B 1 417 ? 4.410   -40.382 -28.318 1.00 56.37  ? 417 LEU B CG  1 
ATOM   6925  C CD1 . LEU B 1 417 ? 3.183   -41.112 -27.791 1.00 57.53  ? 417 LEU B CD1 1 
ATOM   6926  C CD2 . LEU B 1 417 ? 5.063   -41.167 -29.457 1.00 62.00  ? 417 LEU B CD2 1 
ATOM   6927  N N   . PRO B 1 418 ? 3.978   -36.857 -31.282 1.00 46.81  ? 418 PRO B N   1 
ATOM   6928  C CA  . PRO B 1 418 ? 3.557   -35.567 -31.843 1.00 40.82  ? 418 PRO B CA  1 
ATOM   6929  C C   . PRO B 1 418 ? 2.175   -35.166 -31.331 1.00 43.52  ? 418 PRO B C   1 
ATOM   6930  O O   . PRO B 1 418 ? 1.557   -35.886 -30.560 1.00 45.37  ? 418 PRO B O   1 
ATOM   6931  C CB  . PRO B 1 418 ? 3.583   -35.900 -33.349 1.00 41.97  ? 418 PRO B CB  1 
ATOM   6932  C CG  . PRO B 1 418 ? 3.072   -37.339 -33.364 1.00 44.30  ? 418 PRO B CG  1 
ATOM   6933  C CD  . PRO B 1 418 ? 3.799   -37.996 -32.197 1.00 40.54  ? 418 PRO B CD  1 
ATOM   6934  N N   . ILE B 1 419 ? 1.674   -34.030 -31.818 1.00 44.30  ? 419 ILE B N   1 
ATOM   6935  C CA  . ILE B 1 419 ? 0.379   -33.518 -31.430 1.00 45.23  ? 419 ILE B CA  1 
ATOM   6936  C C   . ILE B 1 419 ? -0.740  -34.476 -31.848 1.00 47.82  ? 419 ILE B C   1 
ATOM   6937  O O   . ILE B 1 419 ? -0.733  -35.064 -32.915 1.00 47.48  ? 419 ILE B O   1 
ATOM   6938  C CB  . ILE B 1 419 ? 0.182   -32.110 -32.023 1.00 43.32  ? 419 ILE B CB  1 
ATOM   6939  C CG1 . ILE B 1 419 ? -1.008  -31.405 -31.373 1.00 41.80  ? 419 ILE B CG1 1 
ATOM   6940  C CG2 . ILE B 1 419 ? 0.053   -32.134 -33.540 1.00 41.15  ? 419 ILE B CG2 1 
ATOM   6941  C CD1 . ILE B 1 419 ? -1.122  -29.947 -31.768 1.00 45.09  ? 419 ILE B CD1 1 
ATOM   6942  N N   . GLU B 1 420 ? -1.752  -34.599 -31.003 1.00 45.19  ? 420 GLU B N   1 
ATOM   6943  C CA  . GLU B 1 420 ? -2.926  -35.368 -31.359 1.00 46.38  ? 420 GLU B CA  1 
ATOM   6944  C C   . GLU B 1 420 ? -3.825  -34.535 -32.268 1.00 50.05  ? 420 GLU B C   1 
ATOM   6945  O O   . GLU B 1 420 ? -4.346  -33.503 -31.843 1.00 45.36  ? 420 GLU B O   1 
ATOM   6946  C CB  . GLU B 1 420 ? -3.605  -35.809 -30.074 1.00 50.65  ? 420 GLU B CB  1 
ATOM   6947  C CG  . GLU B 1 420 ? -4.519  -37.001 -30.207 1.00 54.78  ? 420 GLU B CG  1 
ATOM   6948  C CD  . GLU B 1 420 ? -5.082  -37.399 -28.850 1.00 61.28  ? 420 GLU B CD  1 
ATOM   6949  O OE1 . GLU B 1 420 ? -6.328  -37.443 -28.724 1.00 57.48  ? 420 GLU B OE1 1 
ATOM   6950  O OE2 . GLU B 1 420 ? -4.271  -37.596 -27.899 1.00 64.76  ? 420 GLU B OE2 1 
ATOM   6951  N N   . ARG B 1 421 ? -3.994  -34.976 -33.528 1.00 50.07  ? 421 ARG B N   1 
ATOM   6952  C CA  . ARG B 1 421 ? -4.904  -34.324 -34.461 1.00 53.16  ? 421 ARG B CA  1 
ATOM   6953  C C   . ARG B 1 421 ? -5.570  -35.391 -35.339 1.00 54.77  ? 421 ARG B C   1 
ATOM   6954  O O   . ARG B 1 421 ? -5.185  -35.641 -36.483 1.00 51.72  ? 421 ARG B O   1 
ATOM   6955  C CB  . ARG B 1 421 ? -4.168  -33.259 -35.282 1.00 57.98  ? 421 ARG B CB  1 
ATOM   6956  C CG  . ARG B 1 421 ? -5.037  -32.095 -35.758 1.00 64.08  ? 421 ARG B CG  1 
ATOM   6957  C CD  . ARG B 1 421 ? -5.943  -32.314 -36.968 1.00 66.10  ? 421 ARG B CD  1 
ATOM   6958  N NE  . ARG B 1 421 ? -6.530  -31.063 -37.463 1.00 73.61  ? 421 ARG B NE  1 
ATOM   6959  C CZ  . ARG B 1 421 ? -7.822  -30.848 -37.774 1.00 72.15  ? 421 ARG B CZ  1 
ATOM   6960  N NH1 . ARG B 1 421 ? -8.190  -29.635 -38.146 1.00 68.58  ? 421 ARG B NH1 1 
ATOM   6961  N NH2 . ARG B 1 421 ? -8.743  -31.808 -37.722 1.00 65.51  ? 421 ARG B NH2 1 
ATOM   6962  N N   . PRO B 1 422 ? -6.621  -36.040 -34.818 1.00 47.86  ? 422 PRO B N   1 
ATOM   6963  C CA  . PRO B 1 422 ? -7.517  -36.850 -35.630 1.00 50.01  ? 422 PRO B CA  1 
ATOM   6964  C C   . PRO B 1 422 ? -8.307  -36.045 -36.660 1.00 49.46  ? 422 PRO B C   1 
ATOM   6965  O O   . PRO B 1 422 ? -8.363  -34.827 -36.588 1.00 48.62  ? 422 PRO B O   1 
ATOM   6966  C CB  . PRO B 1 422 ? -8.499  -37.452 -34.605 1.00 46.34  ? 422 PRO B CB  1 
ATOM   6967  C CG  . PRO B 1 422 ? -8.461  -36.493 -33.448 1.00 55.04  ? 422 PRO B CG  1 
ATOM   6968  C CD  . PRO B 1 422 ? -7.039  -35.964 -33.412 1.00 51.96  ? 422 PRO B CD  1 
ATOM   6969  N N   . LYS B 1 423 ? -8.927  -36.760 -37.605 1.00 49.58  ? 423 LYS B N   1 
ATOM   6970  C CA  . LYS B 1 423 ? -9.807  -36.192 -38.606 1.00 51.44  ? 423 LYS B CA  1 
ATOM   6971  C C   . LYS B 1 423 ? -11.253 -36.350 -38.137 1.00 46.40  ? 423 LYS B C   1 
ATOM   6972  O O   . LYS B 1 423 ? -11.625 -37.423 -37.716 1.00 48.44  ? 423 LYS B O   1 
ATOM   6973  C CB  . LYS B 1 423 ? -9.588  -36.949 -39.922 1.00 60.62  ? 423 LYS B CB  1 
ATOM   6974  C CG  . LYS B 1 423 ? -10.395 -36.461 -41.122 1.00 63.40  ? 423 LYS B CG  1 
ATOM   6975  C CD  . LYS B 1 423 ? -10.052 -35.045 -41.534 1.00 74.04  ? 423 LYS B CD  1 
ATOM   6976  C CE  . LYS B 1 423 ? -11.057 -34.437 -42.492 1.00 74.62  ? 423 LYS B CE  1 
ATOM   6977  N NZ  . LYS B 1 423 ? -10.577 -33.117 -42.954 1.00 80.33  ? 423 LYS B NZ  1 
ATOM   6978  N N   . SER B 1 424 ? -12.070 -35.296 -38.202 1.00 45.31  ? 424 SER B N   1 
ATOM   6979  C CA  . SER B 1 424 ? -13.490 -35.441 -37.938 1.00 46.79  ? 424 SER B CA  1 
ATOM   6980  C C   . SER B 1 424 ? -14.185 -35.622 -39.283 1.00 48.18  ? 424 SER B C   1 
ATOM   6981  O O   . SER B 1 424 ? -13.599 -35.292 -40.297 1.00 42.33  ? 424 SER B O   1 
ATOM   6982  C CB  . SER B 1 424 ? -14.052 -34.254 -37.153 1.00 47.00  ? 424 SER B CB  1 
ATOM   6983  O OG  . SER B 1 424 ? -13.983 -33.054 -37.901 1.00 46.79  ? 424 SER B OG  1 
ATOM   6984  N N   . ILE B 1 425 ? -15.426 -36.141 -39.257 1.00 57.32  ? 425 ILE B N   1 
ATOM   6985  C CA  . ILE B 1 425 ? -16.245 -36.364 -40.442 1.00 57.32  ? 425 ILE B CA  1 
ATOM   6986  C C   . ILE B 1 425 ? -17.610 -35.707 -40.231 1.00 57.29  ? 425 ILE B C   1 
ATOM   6987  O O   . ILE B 1 425 ? -18.067 -35.522 -39.098 1.00 54.62  ? 425 ILE B O   1 
ATOM   6988  C CB  . ILE B 1 425 ? -16.379 -37.876 -40.762 1.00 61.13  ? 425 ILE B CB  1 
ATOM   6989  C CG1 . ILE B 1 425 ? -17.172 -38.651 -39.705 1.00 60.73  ? 425 ILE B CG1 1 
ATOM   6990  C CG2 . ILE B 1 425 ? -15.017 -38.519 -40.991 1.00 60.91  ? 425 ILE B CG2 1 
ATOM   6991  C CD1 . ILE B 1 425 ? -17.178 -40.171 -39.930 1.00 57.51  ? 425 ILE B CD1 1 
ATOM   6992  N N   . THR B 1 426 ? -18.255 -35.347 -41.345 1.00 49.87  ? 426 THR B N   1 
ATOM   6993  C CA  . THR B 1 426 ? -19.591 -34.789 -41.288 1.00 52.77  ? 426 THR B CA  1 
ATOM   6994  C C   . THR B 1 426 ? -20.619 -35.894 -41.511 1.00 52.95  ? 426 THR B C   1 
ATOM   6995  O O   . THR B 1 426 ? -20.371 -36.827 -42.269 1.00 51.63  ? 426 THR B O   1 
ATOM   6996  C CB  . THR B 1 426 ? -19.779 -33.671 -42.322 1.00 57.32  ? 426 THR B CB  1 
ATOM   6997  O OG1 . THR B 1 426 ? -19.609 -34.249 -43.619 1.00 58.16  ? 426 THR B OG1 1 
ATOM   6998  C CG2 . THR B 1 426 ? -18.838 -32.497 -42.118 1.00 47.95  ? 426 THR B CG2 1 
ATOM   6999  N N   . THR B 1 427 ? -21.771 -35.746 -40.845 1.00 52.05  ? 427 THR B N   1 
ATOM   7000  C CA  . THR B 1 427 ? -22.971 -36.517 -41.121 1.00 61.41  ? 427 THR B CA  1 
ATOM   7001  C C   . THR B 1 427 ? -23.330 -36.424 -42.606 1.00 66.77  ? 427 THR B C   1 
ATOM   7002  O O   . THR B 1 427 ? -23.780 -37.412 -43.176 1.00 74.07  ? 427 THR B O   1 
ATOM   7003  C CB  . THR B 1 427 ? -24.113 -36.085 -40.191 1.00 56.84  ? 427 THR B CB  1 
ATOM   7004  O OG1 . THR B 1 427 ? -23.698 -36.411 -38.868 1.00 62.31  ? 427 THR B OG1 1 
ATOM   7005  C CG2 . THR B 1 427 ? -25.440 -36.765 -40.445 1.00 54.82  ? 427 THR B CG2 1 
ATOM   7006  N N   . ARG B 1 428 ? -23.093 -35.269 -43.246 1.00 69.88  ? 428 ARG B N   1 
ATOM   7007  C CA  . ARG B 1 428 ? -23.305 -35.125 -44.684 1.00 78.58  ? 428 ARG B CA  1 
ATOM   7008  C C   . ARG B 1 428 ? -22.534 -36.177 -45.501 1.00 73.49  ? 428 ARG B C   1 
ATOM   7009  O O   . ARG B 1 428 ? -23.147 -36.909 -46.275 1.00 74.07  ? 428 ARG B O   1 
ATOM   7010  C CB  . ARG B 1 428 ? -22.898 -33.736 -45.181 1.00 82.64  ? 428 ARG B CB  1 
ATOM   7011  C CG  . ARG B 1 428 ? -23.293 -33.474 -46.628 1.00 99.63  ? 428 ARG B CG  1 
ATOM   7012  C CD  . ARG B 1 428 ? -22.371 -32.504 -47.345 1.00 114.47 ? 428 ARG B CD  1 
ATOM   7013  N NE  . ARG B 1 428 ? -22.757 -32.306 -48.742 1.00 136.62 ? 428 ARG B NE  1 
ATOM   7014  C CZ  . ARG B 1 428 ? -23.898 -31.750 -49.158 1.00 126.86 ? 428 ARG B CZ  1 
ATOM   7015  N NH1 . ARG B 1 428 ? -24.825 -31.380 -48.288 1.00 123.33 ? 428 ARG B NH1 1 
ATOM   7016  N NH2 . ARG B 1 428 ? -24.111 -31.566 -50.451 1.00 106.60 ? 428 ARG B NH2 1 
ATOM   7017  N N   . TRP B 1 429 ? -21.195 -36.194 -45.382 1.00 62.50  ? 429 TRP B N   1 
ATOM   7018  C CA  . TRP B 1 429 ? -20.331 -37.172 -46.032 1.00 67.05  ? 429 TRP B CA  1 
ATOM   7019  C C   . TRP B 1 429 ? -20.794 -38.601 -45.759 1.00 73.22  ? 429 TRP B C   1 
ATOM   7020  O O   . TRP B 1 429 ? -20.847 -39.424 -46.667 1.00 83.47  ? 429 TRP B O   1 
ATOM   7021  C CB  . TRP B 1 429 ? -18.902 -37.007 -45.527 1.00 64.75  ? 429 TRP B CB  1 
ATOM   7022  C CG  . TRP B 1 429 ? -17.868 -37.908 -46.132 1.00 67.46  ? 429 TRP B CG  1 
ATOM   7023  C CD1 . TRP B 1 429 ? -17.186 -37.708 -47.297 1.00 72.71  ? 429 TRP B CD1 1 
ATOM   7024  C CD2 . TRP B 1 429 ? -17.296 -39.089 -45.546 1.00 68.40  ? 429 TRP B CD2 1 
ATOM   7025  N NE1 . TRP B 1 429 ? -16.251 -38.690 -47.488 1.00 71.60  ? 429 TRP B NE1 1 
ATOM   7026  C CE2 . TRP B 1 429 ? -16.288 -39.547 -46.429 1.00 65.41  ? 429 TRP B CE2 1 
ATOM   7027  C CE3 . TRP B 1 429 ? -17.525 -39.791 -44.360 1.00 64.27  ? 429 TRP B CE3 1 
ATOM   7028  C CZ2 . TRP B 1 429 ? -15.511 -40.668 -46.165 1.00 60.33  ? 429 TRP B CZ2 1 
ATOM   7029  C CZ3 . TRP B 1 429 ? -16.778 -40.916 -44.108 1.00 59.15  ? 429 TRP B CZ3 1 
ATOM   7030  C CH2 . TRP B 1 429 ? -15.791 -41.346 -45.004 1.00 68.70  ? 429 TRP B CH2 1 
ATOM   7031  N N   . VAL B 1 430 ? -21.094 -38.900 -44.492 1.00 70.12  ? 430 VAL B N   1 
ATOM   7032  C CA  . VAL B 1 430 ? -21.550 -40.229 -44.129 1.00 74.15  ? 430 VAL B CA  1 
ATOM   7033  C C   . VAL B 1 430 ? -22.725 -40.610 -45.032 1.00 69.37  ? 430 VAL B C   1 
ATOM   7034  O O   . VAL B 1 430 ? -22.633 -41.582 -45.771 1.00 72.52  ? 430 VAL B O   1 
ATOM   7035  C CB  . VAL B 1 430 ? -21.910 -40.316 -42.633 1.00 66.54  ? 430 VAL B CB  1 
ATOM   7036  C CG1 . VAL B 1 430 ? -22.654 -41.602 -42.305 1.00 66.77  ? 430 VAL B CG1 1 
ATOM   7037  C CG2 . VAL B 1 430 ? -20.674 -40.166 -41.759 1.00 65.37  ? 430 VAL B CG2 1 
ATOM   7038  N N   . LYS B 1 431 ? -23.799 -39.815 -44.992 1.00 68.52  ? 431 LYS B N   1 
ATOM   7039  C CA  . LYS B 1 431 ? -25.007 -40.070 -45.764 1.00 71.91  ? 431 LYS B CA  1 
ATOM   7040  C C   . LYS B 1 431 ? -24.695 -40.169 -47.259 1.00 69.71  ? 431 LYS B C   1 
ATOM   7041  O O   . LYS B 1 431 ? -25.222 -41.041 -47.921 1.00 64.36  ? 431 LYS B O   1 
ATOM   7042  C CB  . LYS B 1 431 ? -26.071 -38.993 -45.506 1.00 65.73  ? 431 LYS B CB  1 
ATOM   7043  C CG  . LYS B 1 431 ? -26.772 -39.079 -44.157 1.00 67.61  ? 431 LYS B CG  1 
ATOM   7044  C CD  . LYS B 1 431 ? -27.816 -38.012 -43.959 1.00 78.27  ? 431 LYS B CD  1 
ATOM   7045  C CE  . LYS B 1 431 ? -29.104 -38.302 -44.703 1.00 92.55  ? 431 LYS B CE  1 
ATOM   7046  N NZ  . LYS B 1 431 ? -29.831 -37.058 -45.066 1.00 87.23  ? 431 LYS B NZ  1 
ATOM   7047  N N   . GLU B 1 432 ? -23.833 -39.305 -47.800 1.00 76.37  ? 432 GLU B N   1 
ATOM   7048  C CA  . GLU B 1 432 ? -23.473 -39.396 -49.210 1.00 88.99  ? 432 GLU B CA  1 
ATOM   7049  C C   . GLU B 1 432 ? -22.782 -40.730 -49.521 1.00 87.97  ? 432 GLU B C   1 
ATOM   7050  O O   . GLU B 1 432 ? -22.938 -41.250 -50.620 1.00 96.90  ? 432 GLU B O   1 
ATOM   7051  C CB  . GLU B 1 432 ? -22.559 -38.233 -49.617 1.00 93.99  ? 432 GLU B CB  1 
ATOM   7052  C CG  . GLU B 1 432 ? -22.216 -38.189 -51.106 1.00 101.63 ? 432 GLU B CG  1 
ATOM   7053  C CD  . GLU B 1 432 ? -21.110 -37.218 -51.513 1.00 108.72 ? 432 GLU B CD  1 
ATOM   7054  O OE1 . GLU B 1 432 ? -21.430 -36.222 -52.187 1.00 105.07 ? 432 GLU B OE1 1 
ATOM   7055  O OE2 . GLU B 1 432 ? -19.921 -37.462 -51.183 1.00 92.70  ? 432 GLU B OE2 1 
ATOM   7056  N N   . VAL B 1 433 ? -22.020 -41.280 -48.566 1.00 75.97  ? 433 VAL B N   1 
ATOM   7057  C CA  . VAL B 1 433 ? -21.004 -42.278 -48.857 1.00 62.68  ? 433 VAL B CA  1 
ATOM   7058  C C   . VAL B 1 433 ? -21.284 -43.615 -48.149 1.00 65.53  ? 433 VAL B C   1 
ATOM   7059  O O   . VAL B 1 433 ? -20.579 -44.600 -48.369 1.00 67.14  ? 433 VAL B O   1 
ATOM   7060  C CB  . VAL B 1 433 ? -19.634 -41.669 -48.499 1.00 67.82  ? 433 VAL B CB  1 
ATOM   7061  C CG1 . VAL B 1 433 ? -18.675 -42.622 -47.785 1.00 66.08  ? 433 VAL B CG1 1 
ATOM   7062  C CG2 . VAL B 1 433 ? -18.979 -41.049 -49.724 1.00 71.16  ? 433 VAL B CG2 1 
ATOM   7063  N N   . ALA B 1 434 ? -22.344 -43.694 -47.340 1.00 72.54  ? 434 ALA B N   1 
ATOM   7064  C CA  . ALA B 1 434 ? -22.523 -44.819 -46.433 1.00 72.65  ? 434 ALA B CA  1 
ATOM   7065  C C   . ALA B 1 434 ? -22.701 -46.125 -47.215 1.00 78.94  ? 434 ALA B C   1 
ATOM   7066  O O   . ALA B 1 434 ? -21.859 -47.016 -47.101 1.00 66.46  ? 434 ALA B O   1 
ATOM   7067  C CB  . ALA B 1 434 ? -23.687 -44.556 -45.508 1.00 69.52  ? 434 ALA B CB  1 
ATOM   7068  N N   . GLU B 1 435 ? -23.786 -46.204 -48.013 1.00 85.10  ? 435 GLU B N   1 
ATOM   7069  C CA  . GLU B 1 435 ? -24.104 -47.327 -48.903 1.00 82.92  ? 435 GLU B CA  1 
ATOM   7070  C C   . GLU B 1 435 ? -22.866 -47.802 -49.665 1.00 72.37  ? 435 GLU B C   1 
ATOM   7071  O O   . GLU B 1 435 ? -22.642 -48.998 -49.830 1.00 69.66  ? 435 GLU B O   1 
ATOM   7072  C CB  . GLU B 1 435 ? -25.141 -46.942 -49.970 1.00 85.16  ? 435 GLU B CB  1 
ATOM   7073  C CG  . GLU B 1 435 ? -26.497 -46.496 -49.434 1.00 90.98  ? 435 GLU B CG  1 
ATOM   7074  C CD  . GLU B 1 435 ? -27.388 -47.608 -48.915 1.00 89.37  ? 435 GLU B CD  1 
ATOM   7075  O OE1 . GLU B 1 435 ? -27.040 -48.197 -47.887 1.00 77.34  ? 435 GLU B OE1 1 
ATOM   7076  O OE2 . GLU B 1 435 ? -28.430 -47.875 -49.548 1.00 100.17 ? 435 GLU B OE2 1 
ATOM   7077  N N   . SER B 1 436 ? -22.062 -46.834 -50.111 1.00 78.74  ? 436 SER B N   1 
ATOM   7078  C CA  . SER B 1 436 ? -20.856 -47.046 -50.898 1.00 77.54  ? 436 SER B CA  1 
ATOM   7079  C C   . SER B 1 436 ? -19.760 -47.787 -50.132 1.00 72.14  ? 436 SER B C   1 
ATOM   7080  O O   . SER B 1 436 ? -18.736 -48.136 -50.711 1.00 78.22  ? 436 SER B O   1 
ATOM   7081  C CB  . SER B 1 436 ? -20.350 -45.689 -51.339 1.00 94.08  ? 436 SER B CB  1 
ATOM   7082  O OG  . SER B 1 436 ? -21.438 -44.847 -51.736 1.00 88.30  ? 436 SER B OG  1 
ATOM   7083  N N   . LEU B 1 437 ? -19.929 -47.952 -48.816 1.00 71.66  ? 437 LEU B N   1 
ATOM   7084  C CA  . LEU B 1 437 ? -18.853 -48.425 -47.960 1.00 71.68  ? 437 LEU B CA  1 
ATOM   7085  C C   . LEU B 1 437 ? -19.016 -49.914 -47.643 1.00 64.03  ? 437 LEU B C   1 
ATOM   7086  O O   . LEU B 1 437 ? -20.126 -50.407 -47.382 1.00 58.61  ? 437 LEU B O   1 
ATOM   7087  C CB  . LEU B 1 437 ? -18.849 -47.583 -46.677 1.00 77.71  ? 437 LEU B CB  1 
ATOM   7088  C CG  . LEU B 1 437 ? -17.698 -46.596 -46.483 1.00 80.12  ? 437 LEU B CG  1 
ATOM   7089  C CD1 . LEU B 1 437 ? -17.232 -45.959 -47.782 1.00 85.01  ? 437 LEU B CD1 1 
ATOM   7090  C CD2 . LEU B 1 437 ? -18.126 -45.515 -45.503 1.00 75.53  ? 437 LEU B CD2 1 
ATOM   7091  N N   . PRO B 1 438 ? -17.890 -50.659 -47.599 1.00 51.78  ? 438 PRO B N   1 
ATOM   7092  C CA  . PRO B 1 438 ? -17.915 -52.078 -47.247 1.00 63.71  ? 438 PRO B CA  1 
ATOM   7093  C C   . PRO B 1 438 ? -18.217 -52.277 -45.765 1.00 65.18  ? 438 PRO B C   1 
ATOM   7094  O O   . PRO B 1 438 ? -17.752 -51.493 -44.950 1.00 68.62  ? 438 PRO B O   1 
ATOM   7095  C CB  . PRO B 1 438 ? -16.490 -52.559 -47.552 1.00 58.37  ? 438 PRO B CB  1 
ATOM   7096  C CG  . PRO B 1 438 ? -15.640 -51.316 -47.382 1.00 57.75  ? 438 PRO B CG  1 
ATOM   7097  C CD  . PRO B 1 438 ? -16.522 -50.161 -47.820 1.00 52.97  ? 438 PRO B CD  1 
ATOM   7098  N N   . VAL B 1 439 ? -19.013 -53.306 -45.441 1.00 65.29  ? 439 VAL B N   1 
ATOM   7099  C CA  . VAL B 1 439 ? -19.167 -53.770 -44.070 1.00 71.65  ? 439 VAL B CA  1 
ATOM   7100  C C   . VAL B 1 439 ? -17.833 -54.378 -43.621 1.00 72.17  ? 439 VAL B C   1 
ATOM   7101  O O   . VAL B 1 439 ? -17.092 -54.919 -44.429 1.00 67.29  ? 439 VAL B O   1 
ATOM   7102  C CB  . VAL B 1 439 ? -20.381 -54.714 -43.921 1.00 76.15  ? 439 VAL B CB  1 
ATOM   7103  C CG1 . VAL B 1 439 ? -20.463 -55.742 -45.046 1.00 98.89  ? 439 VAL B CG1 1 
ATOM   7104  C CG2 . VAL B 1 439 ? -20.442 -55.393 -42.553 1.00 72.61  ? 439 VAL B CG2 1 
ATOM   7105  N N   . ALA B 1 440 ? -17.480 -54.184 -42.342 1.00 71.15  ? 440 ALA B N   1 
ATOM   7106  C CA  . ALA B 1 440 ? -16.141 -54.471 -41.852 1.00 61.50  ? 440 ALA B CA  1 
ATOM   7107  C C   . ALA B 1 440 ? -16.031 -55.946 -41.500 1.00 59.91  ? 440 ALA B C   1 
ATOM   7108  O O   . ALA B 1 440 ? -16.997 -56.525 -40.991 1.00 54.75  ? 440 ALA B O   1 
ATOM   7109  C CB  . ALA B 1 440 ? -15.864 -53.627 -40.639 1.00 73.75  ? 440 ALA B CB  1 
ATOM   7110  N N   . GLY B 1 441 ? -14.835 -56.509 -41.725 1.00 54.83  ? 441 GLY B N   1 
ATOM   7111  C CA  . GLY B 1 441 ? -14.638 -57.951 -41.667 1.00 59.97  ? 441 GLY B CA  1 
ATOM   7112  C C   . GLY B 1 441 ? -15.511 -58.719 -42.672 1.00 71.02  ? 441 GLY B C   1 
ATOM   7113  O O   . GLY B 1 441 ? -15.920 -59.846 -42.419 1.00 74.21  ? 441 GLY B O   1 
ATOM   7114  N N   . SER B 1 442 ? -15.836 -58.104 -43.813 1.00 76.85  ? 442 SER B N   1 
ATOM   7115  C CA  . SER B 1 442 ? -16.689 -58.738 -44.806 1.00 77.20  ? 442 SER B CA  1 
ATOM   7116  C C   . SER B 1 442 ? -15.862 -59.023 -46.052 1.00 71.84  ? 442 SER B C   1 
ATOM   7117  O O   . SER B 1 442 ? -14.723 -58.557 -46.159 1.00 64.06  ? 442 SER B O   1 
ATOM   7118  C CB  . SER B 1 442 ? -17.916 -57.899 -45.144 1.00 74.03  ? 442 SER B CB  1 
ATOM   7119  O OG  . SER B 1 442 ? -17.652 -56.960 -46.190 1.00 67.56  ? 442 SER B OG  1 
ATOM   7120  N N   . LYS B 1 443 ? -16.467 -59.794 -46.971 1.00 67.51  ? 443 LYS B N   1 
ATOM   7121  C CA  . LYS B 1 443 ? -15.814 -60.178 -48.210 1.00 61.22  ? 443 LYS B CA  1 
ATOM   7122  C C   . LYS B 1 443 ? -15.589 -58.909 -49.036 1.00 50.00  ? 443 LYS B C   1 
ATOM   7123  O O   . LYS B 1 443 ? -14.487 -58.676 -49.514 1.00 58.17  ? 443 LYS B O   1 
ATOM   7124  C CB  . LYS B 1 443 ? -16.643 -61.268 -48.913 1.00 72.45  ? 443 LYS B CB  1 
ATOM   7125  N N   . LEU B 1 444 ? -16.607 -58.043 -49.135 1.00 52.85  ? 444 LEU B N   1 
ATOM   7126  C CA  . LEU B 1 444 ? -16.456 -56.766 -49.824 1.00 60.98  ? 444 LEU B CA  1 
ATOM   7127  C C   . LEU B 1 444 ? -15.299 -55.970 -49.203 1.00 72.10  ? 444 LEU B C   1 
ATOM   7128  O O   . LEU B 1 444 ? -14.467 -55.444 -49.951 1.00 62.88  ? 444 LEU B O   1 
ATOM   7129  C CB  . LEU B 1 444 ? -17.772 -55.971 -49.798 1.00 55.90  ? 444 LEU B CB  1 
ATOM   7130  C CG  . LEU B 1 444 ? -18.175 -55.238 -51.090 1.00 69.28  ? 444 LEU B CG  1 
ATOM   7131  C CD1 . LEU B 1 444 ? -18.836 -53.890 -50.793 1.00 70.50  ? 444 LEU B CD1 1 
ATOM   7132  C CD2 . LEU B 1 444 ? -17.011 -55.054 -52.077 1.00 67.45  ? 444 LEU B CD2 1 
ATOM   7133  N N   . ALA B 1 445 ? -15.227 -55.925 -47.847 1.00 72.96  ? 445 ALA B N   1 
ATOM   7134  C CA  . ALA B 1 445 ? -14.167 -55.205 -47.138 1.00 78.70  ? 445 ALA B CA  1 
ATOM   7135  C C   . ALA B 1 445 ? -12.795 -55.773 -47.493 1.00 57.49  ? 445 ALA B C   1 
ATOM   7136  O O   . ALA B 1 445 ? -11.847 -55.024 -47.663 1.00 58.68  ? 445 ALA B O   1 
ATOM   7137  C CB  . ALA B 1 445 ? -14.368 -55.231 -45.630 1.00 78.88  ? 445 ALA B CB  1 
ATOM   7138  N N   . ALA B 1 446 ? -12.696 -57.104 -47.558 1.00 65.40  ? 446 ALA B N   1 
ATOM   7139  C CA  . ALA B 1 446 ? -11.492 -57.771 -48.041 1.00 68.81  ? 446 ALA B CA  1 
ATOM   7140  C C   . ALA B 1 446 ? -11.205 -57.371 -49.491 1.00 68.90  ? 446 ALA B C   1 
ATOM   7141  O O   . ALA B 1 446 ? -10.050 -57.227 -49.885 1.00 67.76  ? 446 ALA B O   1 
ATOM   7142  C CB  . ALA B 1 446 ? -11.658 -59.269 -47.898 1.00 67.32  ? 446 ALA B CB  1 
ATOM   7143  N N   . ALA B 1 447 ? -12.272 -57.193 -50.288 1.00 84.68  ? 447 ALA B N   1 
ATOM   7144  C CA  . ALA B 1 447 ? -12.135 -56.823 -51.691 1.00 92.89  ? 447 ALA B CA  1 
ATOM   7145  C C   . ALA B 1 447 ? -11.402 -55.488 -51.798 1.00 99.42  ? 447 ALA B C   1 
ATOM   7146  O O   . ALA B 1 447 ? -10.426 -55.365 -52.529 1.00 121.37 ? 447 ALA B O   1 
ATOM   7147  C CB  . ALA B 1 447 ? -13.482 -56.769 -52.378 1.00 79.53  ? 447 ALA B CB  1 
ATOM   7148  N N   . LEU B 1 448 ? -11.853 -54.494 -51.034 1.00 100.30 ? 448 LEU B N   1 
ATOM   7149  C CA  . LEU B 1 448 ? -11.254 -53.172 -51.083 1.00 99.69  ? 448 LEU B CA  1 
ATOM   7150  C C   . LEU B 1 448 ? -10.027 -53.148 -50.163 1.00 109.58 ? 448 LEU B C   1 
ATOM   7151  O O   . LEU B 1 448 ? -10.011 -52.426 -49.166 1.00 106.33 ? 448 LEU B O   1 
ATOM   7152  C CB  . LEU B 1 448 ? -12.340 -52.157 -50.698 1.00 99.17  ? 448 LEU B CB  1 
ATOM   7153  C CG  . LEU B 1 448 ? -13.658 -52.261 -51.480 1.00 96.98  ? 448 LEU B CG  1 
ATOM   7154  C CD1 . LEU B 1 448 ? -14.648 -51.184 -51.053 1.00 89.91  ? 448 LEU B CD1 1 
ATOM   7155  C CD2 . LEU B 1 448 ? -13.430 -52.198 -52.991 1.00 100.34 ? 448 LEU B CD2 1 
ATOM   7156  N N   . GLU B 1 449 ? -8.993  -53.929 -50.544 1.00 112.46 ? 449 GLU B N   1 
ATOM   7157  C CA  . GLU B 1 449 ? -7.809  -54.203 -49.735 1.00 98.17  ? 449 GLU B CA  1 
ATOM   7158  C C   . GLU B 1 449 ? -8.249  -54.490 -48.290 1.00 94.50  ? 449 GLU B C   1 
ATOM   7159  O O   . GLU B 1 449 ? -7.444  -55.073 -47.535 1.00 83.97  ? 449 GLU B O   1 
ATOM   7160  C CB  . GLU B 1 449 ? -6.814  -53.041 -49.834 1.00 92.86  ? 449 GLU B CB  1 
ATOM   7161  C CG  . GLU B 1 449 ? -6.121  -52.920 -51.188 1.00 101.27 ? 449 GLU B CG  1 
ATOM   7162  C CD  . GLU B 1 449 ? -5.608  -51.530 -51.557 1.00 105.70 ? 449 GLU B CD  1 
ATOM   7163  O OE1 . GLU B 1 449 ? -4.395  -51.256 -51.348 1.00 90.77  ? 449 GLU B OE1 1 
ATOM   7164  O OE2 . GLU B 1 449 ? -6.406  -50.731 -52.109 1.00 105.05 ? 449 GLU B OE2 1 
ATOM   7165  N N   . MET C 1 1   ? 19.425  -1.599  28.007  1.00 73.72  ? 1   MET C N   1 
ATOM   7166  C CA  . MET C 1 1   ? 20.258  -1.652  26.773  1.00 67.99  ? 1   MET C CA  1 
ATOM   7167  C C   . MET C 1 1   ? 21.430  -0.674  26.934  1.00 60.75  ? 1   MET C C   1 
ATOM   7168  O O   . MET C 1 1   ? 21.256  0.536   27.157  1.00 52.24  ? 1   MET C O   1 
ATOM   7169  C CB  . MET C 1 1   ? 19.399  -1.324  25.544  1.00 69.33  ? 1   MET C CB  1 
ATOM   7170  C CG  . MET C 1 1   ? 20.153  -1.401  24.233  1.00 75.85  ? 1   MET C CG  1 
ATOM   7171  S SD  . MET C 1 1   ? 19.090  -1.344  22.753  1.00 75.60  ? 1   MET C SD  1 
ATOM   7172  C CE  . MET C 1 1   ? 18.763  0.413   22.656  1.00 74.83  ? 1   MET C CE  1 
ATOM   7173  N N   . LYS C 1 2   ? 22.646  -1.218  26.880  1.00 52.56  ? 2   LYS C N   1 
ATOM   7174  C CA  . LYS C 1 2   ? 23.822  -0.388  27.068  1.00 55.47  ? 2   LYS C CA  1 
ATOM   7175  C C   . LYS C 1 2   ? 23.788  0.770   26.068  1.00 56.41  ? 2   LYS C C   1 
ATOM   7176  O O   . LYS C 1 2   ? 24.057  1.927   26.410  1.00 54.34  ? 2   LYS C O   1 
ATOM   7177  C CB  . LYS C 1 2   ? 25.088  -1.239  26.936  1.00 63.32  ? 2   LYS C CB  1 
ATOM   7178  C CG  . LYS C 1 2   ? 26.379  -0.529  27.339  1.00 77.25  ? 2   LYS C CG  1 
ATOM   7179  C CD  . LYS C 1 2   ? 26.466  -0.226  28.835  1.00 83.30  ? 2   LYS C CD  1 
ATOM   7180  C CE  . LYS C 1 2   ? 27.832  0.263   29.266  1.00 96.85  ? 2   LYS C CE  1 
ATOM   7181  N NZ  . LYS C 1 2   ? 27.988  0.252   30.744  1.00 91.90  ? 2   LYS C NZ  1 
ATOM   7182  N N   . LEU C 1 3   ? 23.397  0.473   24.823  1.00 52.23  ? 3   LEU C N   1 
ATOM   7183  C CA  . LEU C 1 3   ? 23.400  1.511   23.807  1.00 49.80  ? 3   LEU C CA  1 
ATOM   7184  C C   . LEU C 1 3   ? 22.637  2.742   24.286  1.00 45.37  ? 3   LEU C C   1 
ATOM   7185  O O   . LEU C 1 3   ? 23.062  3.861   24.065  1.00 45.21  ? 3   LEU C O   1 
ATOM   7186  C CB  . LEU C 1 3   ? 22.822  0.960   22.500  1.00 50.35  ? 3   LEU C CB  1 
ATOM   7187  C CG  . LEU C 1 3   ? 22.452  2.001   21.447  1.00 53.55  ? 3   LEU C CG  1 
ATOM   7188  C CD1 . LEU C 1 3   ? 23.635  2.884   21.075  1.00 51.57  ? 3   LEU C CD1 1 
ATOM   7189  C CD2 . LEU C 1 3   ? 21.888  1.313   20.211  1.00 59.70  ? 3   LEU C CD2 1 
ATOM   7190  N N   . LYS C 1 4   ? 21.468  2.559   24.895  1.00 48.10  ? 4   LYS C N   1 
ATOM   7191  C CA  . LYS C 1 4   ? 20.645  3.708   25.234  1.00 49.46  ? 4   LYS C CA  1 
ATOM   7192  C C   . LYS C 1 4   ? 21.315  4.480   26.381  1.00 47.46  ? 4   LYS C C   1 
ATOM   7193  O O   . LYS C 1 4   ? 21.528  5.684   26.280  1.00 53.41  ? 4   LYS C O   1 
ATOM   7194  C CB  . LYS C 1 4   ? 19.201  3.270   25.536  1.00 50.38  ? 4   LYS C CB  1 
ATOM   7195  C CG  . LYS C 1 4   ? 18.310  4.435   25.912  1.00 60.71  ? 4   LYS C CG  1 
ATOM   7196  C CD  . LYS C 1 4   ? 16.833  4.149   25.954  1.00 62.69  ? 4   LYS C CD  1 
ATOM   7197  C CE  . LYS C 1 4   ? 16.087  5.380   26.416  1.00 63.54  ? 4   LYS C CE  1 
ATOM   7198  N NZ  . LYS C 1 4   ? 14.743  5.443   25.802  1.00 70.55  ? 4   LYS C NZ  1 
ATOM   7199  N N   . GLU C 1 5   ? 21.718  3.766   27.432  1.00 46.30  ? 5   GLU C N   1 
ATOM   7200  C CA  . GLU C 1 5   ? 22.357  4.364   28.588  1.00 52.27  ? 5   GLU C CA  1 
ATOM   7201  C C   . GLU C 1 5   ? 23.469  5.284   28.108  1.00 55.26  ? 5   GLU C C   1 
ATOM   7202  O O   . GLU C 1 5   ? 23.552  6.435   28.512  1.00 57.64  ? 5   GLU C O   1 
ATOM   7203  C CB  . GLU C 1 5   ? 22.904  3.279   29.520  1.00 56.50  ? 5   GLU C CB  1 
ATOM   7204  C CG  . GLU C 1 5   ? 21.822  2.520   30.292  1.00 64.92  ? 5   GLU C CG  1 
ATOM   7205  C CD  . GLU C 1 5   ? 22.259  1.188   30.899  1.00 76.90  ? 5   GLU C CD  1 
ATOM   7206  O OE1 . GLU C 1 5   ? 21.425  0.514   31.553  1.00 71.68  ? 5   GLU C OE1 1 
ATOM   7207  O OE2 . GLU C 1 5   ? 23.430  0.797   30.690  1.00 86.88  ? 5   GLU C OE2 1 
ATOM   7208  N N   . ARG C 1 6   ? 24.282  4.791   27.179  1.00 56.01  ? 6   ARG C N   1 
ATOM   7209  C CA  . ARG C 1 6   ? 25.445  5.537   26.726  1.00 54.84  ? 6   ARG C CA  1 
ATOM   7210  C C   . ARG C 1 6   ? 24.994  6.778   25.966  1.00 51.24  ? 6   ARG C C   1 
ATOM   7211  O O   . ARG C 1 6   ? 25.570  7.866   26.103  1.00 45.64  ? 6   ARG C O   1 
ATOM   7212  C CB  . ARG C 1 6   ? 26.324  4.595   25.896  1.00 65.74  ? 6   ARG C CB  1 
ATOM   7213  C CG  . ARG C 1 6   ? 27.811  4.890   25.960  1.00 71.43  ? 6   ARG C CG  1 
ATOM   7214  C CD  . ARG C 1 6   ? 28.469  4.808   27.327  1.00 63.75  ? 6   ARG C CD  1 
ATOM   7215  N NE  . ARG C 1 6   ? 29.631  5.675   27.248  1.00 64.46  ? 6   ARG C NE  1 
ATOM   7216  C CZ  . ARG C 1 6   ? 29.640  6.966   27.554  1.00 63.12  ? 6   ARG C CZ  1 
ATOM   7217  N NH1 . ARG C 1 6   ? 28.651  7.490   28.251  1.00 72.80  ? 6   ARG C NH1 1 
ATOM   7218  N NH2 . ARG C 1 6   ? 30.655  7.727   27.182  1.00 55.19  ? 6   ARG C NH2 1 
ATOM   7219  N N   . LEU C 1 7   ? 23.921  6.630   25.185  1.00 48.04  ? 7   LEU C N   1 
ATOM   7220  C CA  . LEU C 1 7   ? 23.446  7.762   24.410  1.00 44.44  ? 7   LEU C CA  1 
ATOM   7221  C C   . LEU C 1 7   ? 22.860  8.804   25.352  1.00 41.04  ? 7   LEU C C   1 
ATOM   7222  O O   . LEU C 1 7   ? 22.942  9.996   25.062  1.00 45.58  ? 7   LEU C O   1 
ATOM   7223  C CB  . LEU C 1 7   ? 22.397  7.292   23.402  1.00 47.14  ? 7   LEU C CB  1 
ATOM   7224  C CG  . LEU C 1 7   ? 22.923  6.654   22.124  1.00 46.67  ? 7   LEU C CG  1 
ATOM   7225  C CD1 . LEU C 1 7   ? 21.757  6.178   21.244  1.00 47.39  ? 7   LEU C CD1 1 
ATOM   7226  C CD2 . LEU C 1 7   ? 23.809  7.638   21.362  1.00 47.73  ? 7   LEU C CD2 1 
ATOM   7227  N N   . ALA C 1 8   ? 22.247  8.331   26.449  1.00 47.95  ? 8   ALA C N   1 
ATOM   7228  C CA  . ALA C 1 8   ? 21.637  9.186   27.467  1.00 55.54  ? 8   ALA C CA  1 
ATOM   7229  C C   . ALA C 1 8   ? 22.643  10.186  28.023  1.00 51.13  ? 8   ALA C C   1 
ATOM   7230  O O   . ALA C 1 8   ? 22.286  11.346  28.231  1.00 54.38  ? 8   ALA C O   1 
ATOM   7231  C CB  . ALA C 1 8   ? 21.065  8.361   28.599  1.00 52.33  ? 8   ALA C CB  1 
ATOM   7232  N N   . GLU C 1 9   ? 23.881  9.721   28.227  1.00 45.47  ? 9   GLU C N   1 
ATOM   7233  C CA  . GLU C 1 9   ? 24.997  10.567  28.647  1.00 52.44  ? 9   GLU C CA  1 
ATOM   7234  C C   . GLU C 1 9   ? 25.622  11.405  27.525  1.00 45.38  ? 9   GLU C C   1 
ATOM   7235  O O   . GLU C 1 9   ? 25.997  12.543  27.756  1.00 51.60  ? 9   GLU C O   1 
ATOM   7236  C CB  . GLU C 1 9   ? 26.084  9.699   29.273  1.00 65.40  ? 9   GLU C CB  1 
ATOM   7237  C CG  . GLU C 1 9   ? 25.662  9.106   30.609  1.00 86.15  ? 9   GLU C CG  1 
ATOM   7238  C CD  . GLU C 1 9   ? 26.801  8.716   31.541  1.00 108.76 ? 9   GLU C CD  1 
ATOM   7239  O OE1 . GLU C 1 9   ? 26.920  7.496   31.834  1.00 112.78 ? 9   GLU C OE1 1 
ATOM   7240  O OE2 . GLU C 1 9   ? 27.562  9.634   31.985  1.00 97.37  ? 9   GLU C OE2 1 
ATOM   7241  N N   . LEU C 1 10  ? 25.791  10.866  26.317  1.00 49.52  ? 10  LEU C N   1 
ATOM   7242  C CA  . LEU C 1 10  ? 26.556  11.577  25.298  1.00 47.34  ? 10  LEU C CA  1 
ATOM   7243  C C   . LEU C 1 10  ? 25.711  12.649  24.642  1.00 45.87  ? 10  LEU C C   1 
ATOM   7244  O O   . LEU C 1 10  ? 26.215  13.722  24.363  1.00 54.50  ? 10  LEU C O   1 
ATOM   7245  C CB  . LEU C 1 10  ? 27.091  10.605  24.240  1.00 51.20  ? 10  LEU C CB  1 
ATOM   7246  C CG  . LEU C 1 10  ? 28.161  9.639   24.736  1.00 50.52  ? 10  LEU C CG  1 
ATOM   7247  C CD1 . LEU C 1 10  ? 28.201  8.381   23.883  1.00 50.40  ? 10  LEU C CD1 1 
ATOM   7248  C CD2 . LEU C 1 10  ? 29.525  10.307  24.748  1.00 53.35  ? 10  LEU C CD2 1 
ATOM   7249  N N   . ILE C 1 11  ? 24.432  12.370  24.369  1.00 52.95  ? 11  ILE C N   1 
ATOM   7250  C CA  . ILE C 1 11  ? 23.652  13.280  23.539  1.00 47.17  ? 11  ILE C CA  1 
ATOM   7251  C C   . ILE C 1 11  ? 23.505  14.658  24.193  1.00 46.23  ? 11  ILE C C   1 
ATOM   7252  O O   . ILE C 1 11  ? 23.684  15.681  23.519  1.00 43.80  ? 11  ILE C O   1 
ATOM   7253  C CB  . ILE C 1 11  ? 22.319  12.625  23.092  1.00 50.63  ? 11  ILE C CB  1 
ATOM   7254  C CG1 . ILE C 1 11  ? 22.584  11.635  21.950  1.00 49.89  ? 11  ILE C CG1 1 
ATOM   7255  C CG2 . ILE C 1 11  ? 21.290  13.670  22.687  1.00 49.25  ? 11  ILE C CG2 1 
ATOM   7256  C CD1 . ILE C 1 11  ? 21.444  10.737  21.588  1.00 48.07  ? 11  ILE C CD1 1 
ATOM   7257  N N   . PRO C 1 12  ? 23.185  14.783  25.505  1.00 47.82  ? 12  PRO C N   1 
ATOM   7258  C CA  . PRO C 1 12  ? 23.158  16.107  26.144  1.00 50.33  ? 12  PRO C CA  1 
ATOM   7259  C C   . PRO C 1 12  ? 24.485  16.850  26.023  1.00 46.70  ? 12  PRO C C   1 
ATOM   7260  O O   . PRO C 1 12  ? 24.500  18.045  25.724  1.00 53.79  ? 12  PRO C O   1 
ATOM   7261  C CB  . PRO C 1 12  ? 22.811  15.811  27.614  1.00 53.60  ? 12  PRO C CB  1 
ATOM   7262  C CG  . PRO C 1 12  ? 22.109  14.459  27.559  1.00 51.63  ? 12  PRO C CG  1 
ATOM   7263  C CD  . PRO C 1 12  ? 22.795  13.708  26.428  1.00 47.88  ? 12  PRO C CD  1 
ATOM   7264  N N   . GLN C 1 13  ? 25.604  16.110  26.141  1.00 51.06  ? 13  GLN C N   1 
ATOM   7265  C CA  . GLN C 1 13  ? 26.928  16.683  25.930  1.00 50.77  ? 13  GLN C CA  1 
ATOM   7266  C C   . GLN C 1 13  ? 27.080  17.209  24.508  1.00 54.87  ? 13  GLN C C   1 
ATOM   7267  O O   . GLN C 1 13  ? 27.478  18.368  24.322  1.00 51.13  ? 13  GLN C O   1 
ATOM   7268  C CB  . GLN C 1 13  ? 28.029  15.675  26.231  1.00 58.31  ? 13  GLN C CB  1 
ATOM   7269  C CG  . GLN C 1 13  ? 28.166  15.360  27.708  1.00 65.29  ? 13  GLN C CG  1 
ATOM   7270  C CD  . GLN C 1 13  ? 29.343  14.446  27.960  1.00 69.64  ? 13  GLN C CD  1 
ATOM   7271  O OE1 . GLN C 1 13  ? 30.349  14.503  27.258  1.00 79.15  ? 13  GLN C OE1 1 
ATOM   7272  N NE2 . GLN C 1 13  ? 29.226  13.588  28.960  1.00 63.81  ? 13  GLN C NE2 1 
ATOM   7273  N N   . TRP C 1 14  ? 26.795  16.346  23.512  1.00 55.53  ? 14  TRP C N   1 
ATOM   7274  C CA  . TRP C 1 14  ? 26.940  16.726  22.110  1.00 46.20  ? 14  TRP C CA  1 
ATOM   7275  C C   . TRP C 1 14  ? 26.061  17.922  21.786  1.00 43.61  ? 14  TRP C C   1 
ATOM   7276  O O   . TRP C 1 14  ? 26.452  18.818  21.014  1.00 41.78  ? 14  TRP C O   1 
ATOM   7277  C CB  . TRP C 1 14  ? 26.630  15.556  21.176  1.00 50.60  ? 14  TRP C CB  1 
ATOM   7278  C CG  . TRP C 1 14  ? 27.661  14.481  21.209  1.00 48.53  ? 14  TRP C CG  1 
ATOM   7279  C CD1 . TRP C 1 14  ? 28.975  14.622  21.524  1.00 49.07  ? 14  TRP C CD1 1 
ATOM   7280  C CD2 . TRP C 1 14  ? 27.469  13.088  20.923  1.00 49.58  ? 14  TRP C CD2 1 
ATOM   7281  N NE1 . TRP C 1 14  ? 29.607  13.409  21.478  1.00 51.07  ? 14  TRP C NE1 1 
ATOM   7282  C CE2 . TRP C 1 14  ? 28.717  12.454  21.094  1.00 47.83  ? 14  TRP C CE2 1 
ATOM   7283  C CE3 . TRP C 1 14  ? 26.374  12.312  20.550  1.00 48.48  ? 14  TRP C CE3 1 
ATOM   7284  C CZ2 . TRP C 1 14  ? 28.906  11.094  20.888  1.00 52.06  ? 14  TRP C CZ2 1 
ATOM   7285  C CZ3 . TRP C 1 14  ? 26.563  10.962  20.331  1.00 46.51  ? 14  TRP C CZ3 1 
ATOM   7286  C CH2 . TRP C 1 14  ? 27.801  10.359  20.521  1.00 50.36  ? 14  TRP C CH2 1 
ATOM   7287  N N   . ARG C 1 15  ? 24.871  17.913  22.393  1.00 48.96  ? 15  ARG C N   1 
ATOM   7288  C CA  . ARG C 1 15  ? 23.904  18.967  22.151  1.00 53.83  ? 15  ARG C CA  1 
ATOM   7289  C C   . ARG C 1 15  ? 24.498  20.302  22.603  1.00 52.89  ? 15  ARG C C   1 
ATOM   7290  O O   . ARG C 1 15  ? 24.427  21.278  21.858  1.00 49.93  ? 15  ARG C O   1 
ATOM   7291  C CB  . ARG C 1 15  ? 22.580  18.638  22.855  1.00 58.94  ? 15  ARG C CB  1 
ATOM   7292  C CG  . ARG C 1 15  ? 21.489  19.683  22.644  1.00 64.09  ? 15  ARG C CG  1 
ATOM   7293  C CD  . ARG C 1 15  ? 20.268  19.402  23.501  1.00 68.25  ? 15  ARG C CD  1 
ATOM   7294  N NE  . ARG C 1 15  ? 19.496  20.629  23.703  1.00 80.70  ? 15  ARG C NE  1 
ATOM   7295  C CZ  . ARG C 1 15  ? 19.102  21.118  24.881  1.00 85.94  ? 15  ARG C CZ  1 
ATOM   7296  N NH1 . ARG C 1 15  ? 19.280  20.436  26.003  1.00 79.73  ? 15  ARG C NH1 1 
ATOM   7297  N NH2 . ARG C 1 15  ? 18.509  22.299  24.927  1.00 91.50  ? 15  ARG C NH2 1 
ATOM   7298  N N   . ALA C 1 16  ? 25.075  20.311  23.823  1.00 53.83  ? 16  ALA C N   1 
ATOM   7299  C CA  . ALA C 1 16  ? 25.688  21.491  24.428  1.00 52.30  ? 16  ALA C CA  1 
ATOM   7300  C C   . ALA C 1 16  ? 26.837  22.005  23.562  1.00 48.59  ? 16  ALA C C   1 
ATOM   7301  O O   . ALA C 1 16  ? 26.951  23.211  23.357  1.00 53.61  ? 16  ALA C O   1 
ATOM   7302  C CB  . ALA C 1 16  ? 26.169  21.168  25.836  1.00 48.81  ? 16  ALA C CB  1 
ATOM   7303  N N   . GLU C 1 17  ? 27.657  21.088  23.032  1.00 46.60  ? 17  GLU C N   1 
ATOM   7304  C CA  . GLU C 1 17  ? 28.799  21.451  22.206  1.00 56.57  ? 17  GLU C CA  1 
ATOM   7305  C C   . GLU C 1 17  ? 28.315  22.068  20.902  1.00 55.49  ? 17  GLU C C   1 
ATOM   7306  O O   . GLU C 1 17  ? 28.887  23.049  20.422  1.00 65.14  ? 17  GLU C O   1 
ATOM   7307  C CB  . GLU C 1 17  ? 29.679  20.238  21.875  1.00 72.00  ? 17  GLU C CB  1 
ATOM   7308  C CG  . GLU C 1 17  ? 30.509  19.682  23.035  1.00 77.56  ? 17  GLU C CG  1 
ATOM   7309  C CD  . GLU C 1 17  ? 31.162  18.327  22.752  1.00 93.23  ? 17  GLU C CD  1 
ATOM   7310  O OE1 . GLU C 1 17  ? 31.695  18.149  21.622  1.00 98.95  ? 17  GLU C OE1 1 
ATOM   7311  O OE2 . GLU C 1 17  ? 31.150  17.439  23.654  1.00 76.84  ? 17  GLU C OE2 1 
ATOM   7312  N N   . VAL C 1 18  ? 27.260  21.486  20.327  1.00 47.33  ? 18  VAL C N   1 
ATOM   7313  C CA  . VAL C 1 18  ? 26.773  21.966  19.046  1.00 52.01  ? 18  VAL C CA  1 
ATOM   7314  C C   . VAL C 1 18  ? 26.221  23.371  19.212  1.00 49.12  ? 18  VAL C C   1 
ATOM   7315  O O   . VAL C 1 18  ? 26.405  24.212  18.324  1.00 51.81  ? 18  VAL C O   1 
ATOM   7316  C CB  . VAL C 1 18  ? 25.716  21.022  18.428  1.00 54.04  ? 18  VAL C CB  1 
ATOM   7317  C CG1 . VAL C 1 18  ? 24.907  21.709  17.342  1.00 53.01  ? 18  VAL C CG1 1 
ATOM   7318  C CG2 . VAL C 1 18  ? 26.349  19.735  17.916  1.00 50.54  ? 18  VAL C CG2 1 
ATOM   7319  N N   . ALA C 1 19  ? 25.452  23.585  20.289  1.00 49.27  ? 19  ALA C N   1 
ATOM   7320  C CA  . ALA C 1 19  ? 24.887  24.907  20.548  1.00 52.27  ? 19  ALA C CA  1 
ATOM   7321  C C   . ALA C 1 19  ? 25.995  25.969  20.554  1.00 53.37  ? 19  ALA C C   1 
ATOM   7322  O O   . ALA C 1 19  ? 25.808  27.038  19.978  1.00 51.59  ? 19  ALA C O   1 
ATOM   7323  C CB  . ALA C 1 19  ? 24.106  24.904  21.847  1.00 47.42  ? 19  ALA C CB  1 
ATOM   7324  N N   . GLU C 1 20  ? 27.140  25.641  21.182  1.00 53.23  ? 20  GLU C N   1 
ATOM   7325  C CA  . GLU C 1 20  ? 28.248  26.572  21.366  1.00 61.99  ? 20  GLU C CA  1 
ATOM   7326  C C   . GLU C 1 20  ? 28.972  26.779  20.038  1.00 51.57  ? 20  GLU C C   1 
ATOM   7327  O O   . GLU C 1 20  ? 29.370  27.893  19.725  1.00 50.31  ? 20  GLU C O   1 
ATOM   7328  C CB  . GLU C 1 20  ? 29.180  26.109  22.502  1.00 66.84  ? 20  GLU C CB  1 
ATOM   7329  C CG  . GLU C 1 20  ? 30.533  26.833  22.568  1.00 89.79  ? 20  GLU C CG  1 
ATOM   7330  C CD  . GLU C 1 20  ? 30.598  28.311  22.973  1.00 96.79  ? 20  GLU C CD  1 
ATOM   7331  O OE1 . GLU C 1 20  ? 29.549  29.006  22.978  1.00 86.04  ? 20  GLU C OE1 1 
ATOM   7332  O OE2 . GLU C 1 20  ? 31.724  28.781  23.287  1.00 93.36  ? 20  GLU C OE2 1 
ATOM   7333  N N   . ILE C 1 21  ? 29.118  25.719  19.237  1.00 59.91  ? 21  ILE C N   1 
ATOM   7334  C CA  . ILE C 1 21  ? 29.733  25.848  17.923  1.00 52.86  ? 21  ILE C CA  1 
ATOM   7335  C C   . ILE C 1 21  ? 28.901  26.790  17.058  1.00 51.91  ? 21  ILE C C   1 
ATOM   7336  O O   . ILE C 1 21  ? 29.474  27.646  16.396  1.00 54.15  ? 21  ILE C O   1 
ATOM   7337  C CB  . ILE C 1 21  ? 29.986  24.465  17.279  1.00 53.55  ? 21  ILE C CB  1 
ATOM   7338  C CG1 . ILE C 1 21  ? 31.092  23.713  18.022  1.00 50.96  ? 21  ILE C CG1 1 
ATOM   7339  C CG2 . ILE C 1 21  ? 30.306  24.564  15.795  1.00 49.52  ? 21  ILE C CG2 1 
ATOM   7340  C CD1 . ILE C 1 21  ? 31.285  22.309  17.539  1.00 52.16  ? 21  ILE C CD1 1 
ATOM   7341  N N   . ARG C 1 22  ? 27.566  26.644  17.047  1.00 51.96  ? 22  ARG C N   1 
ATOM   7342  C CA  . ARG C 1 22  ? 26.727  27.486  16.208  1.00 56.56  ? 22  ARG C CA  1 
ATOM   7343  C C   . ARG C 1 22  ? 26.860  28.950  16.655  1.00 58.58  ? 22  ARG C C   1 
ATOM   7344  O O   . ARG C 1 22  ? 26.833  29.866  15.832  1.00 58.79  ? 22  ARG C O   1 
ATOM   7345  C CB  . ARG C 1 22  ? 25.257  27.020  16.229  1.00 59.40  ? 22  ARG C CB  1 
ATOM   7346  C CG  . ARG C 1 22  ? 25.008  25.626  15.657  1.00 64.15  ? 22  ARG C CG  1 
ATOM   7347  C CD  . ARG C 1 22  ? 23.566  25.151  15.700  1.00 50.14  ? 22  ARG C CD  1 
ATOM   7348  N NE  . ARG C 1 22  ? 22.764  25.974  14.829  1.00 49.47  ? 22  ARG C NE  1 
ATOM   7349  C CZ  . ARG C 1 22  ? 21.448  26.144  14.928  1.00 54.35  ? 22  ARG C CZ  1 
ATOM   7350  N NH1 . ARG C 1 22  ? 20.759  25.488  15.845  1.00 54.39  ? 22  ARG C NH1 1 
ATOM   7351  N NH2 . ARG C 1 22  ? 20.824  26.986  14.111  1.00 50.93  ? 22  ARG C NH2 1 
ATOM   7352  N N   . LYS C 1 23  ? 26.977  29.152  17.974  1.00 53.24  ? 23  LYS C N   1 
ATOM   7353  C CA  . LYS C 1 23  ? 27.072  30.465  18.595  1.00 62.12  ? 23  LYS C CA  1 
ATOM   7354  C C   . LYS C 1 23  ? 28.394  31.145  18.218  1.00 61.58  ? 23  LYS C C   1 
ATOM   7355  O O   . LYS C 1 23  ? 28.397  32.201  17.588  1.00 60.61  ? 23  LYS C O   1 
ATOM   7356  C CB  . LYS C 1 23  ? 26.949  30.296  20.116  1.00 67.25  ? 23  LYS C CB  1 
ATOM   7357  C CG  . LYS C 1 23  ? 26.717  31.568  20.926  1.00 79.97  ? 23  LYS C CG  1 
ATOM   7358  C CD  . LYS C 1 23  ? 26.865  31.324  22.422  1.00 87.34  ? 23  LYS C CD  1 
ATOM   7359  C CE  . LYS C 1 23  ? 26.254  32.403  23.294  1.00 90.13  ? 23  LYS C CE  1 
ATOM   7360  N NZ  . LYS C 1 23  ? 26.178  31.960  24.707  1.00 86.12  ? 23  LYS C NZ  1 
ATOM   7361  N N   . LYS C 1 24  ? 29.511  30.501  18.573  1.00 58.91  ? 24  LYS C N   1 
ATOM   7362  C CA  . LYS C 1 24  ? 30.834  31.104  18.485  1.00 62.71  ? 24  LYS C CA  1 
ATOM   7363  C C   . LYS C 1 24  ? 31.323  31.132  17.031  1.00 65.33  ? 24  LYS C C   1 
ATOM   7364  O O   . LYS C 1 24  ? 31.959  32.101  16.606  1.00 68.98  ? 24  LYS C O   1 
ATOM   7365  C CB  . LYS C 1 24  ? 31.780  30.344  19.427  1.00 69.70  ? 24  LYS C CB  1 
ATOM   7366  C CG  . LYS C 1 24  ? 33.173  30.941  19.597  1.00 87.32  ? 24  LYS C CG  1 
ATOM   7367  C CD  . LYS C 1 24  ? 34.228  30.008  20.204  1.00 87.24  ? 24  LYS C CD  1 
ATOM   7368  C CE  . LYS C 1 24  ? 34.257  29.976  21.717  1.00 91.88  ? 24  LYS C CE  1 
ATOM   7369  N NZ  . LYS C 1 24  ? 35.543  29.429  22.218  1.00 83.21  ? 24  LYS C NZ  1 
ATOM   7370  N N   . TYR C 1 25  ? 31.010  30.086  16.246  1.00 65.66  ? 25  TYR C N   1 
ATOM   7371  C CA  . TYR C 1 25  ? 31.686  29.858  14.972  1.00 58.33  ? 25  TYR C CA  1 
ATOM   7372  C C   . TYR C 1 25  ? 30.738  29.871  13.770  1.00 55.65  ? 25  TYR C C   1 
ATOM   7373  O O   . TYR C 1 25  ? 31.157  29.583  12.655  1.00 57.26  ? 25  TYR C O   1 
ATOM   7374  C CB  . TYR C 1 25  ? 32.438  28.527  15.031  1.00 62.98  ? 25  TYR C CB  1 
ATOM   7375  C CG  . TYR C 1 25  ? 33.561  28.452  16.036  1.00 66.71  ? 25  TYR C CG  1 
ATOM   7376  C CD1 . TYR C 1 25  ? 34.659  29.299  15.950  1.00 73.39  ? 25  TYR C CD1 1 
ATOM   7377  C CD2 . TYR C 1 25  ? 33.562  27.495  17.037  1.00 69.86  ? 25  TYR C CD2 1 
ATOM   7378  C CE1 . TYR C 1 25  ? 35.714  29.210  16.845  1.00 75.38  ? 25  TYR C CE1 1 
ATOM   7379  C CE2 . TYR C 1 25  ? 34.604  27.393  17.947  1.00 76.46  ? 25  TYR C CE2 1 
ATOM   7380  C CZ  . TYR C 1 25  ? 35.683  28.256  17.850  1.00 84.80  ? 25  TYR C CZ  1 
ATOM   7381  O OH  . TYR C 1 25  ? 36.712  28.168  18.753  1.00 91.36  ? 25  TYR C OH  1 
ATOM   7382  N N   . GLY C 1 26  ? 29.464  30.222  13.963  1.00 60.21  ? 26  GLY C N   1 
ATOM   7383  C CA  . GLY C 1 26  ? 28.510  30.287  12.863  1.00 50.74  ? 26  GLY C CA  1 
ATOM   7384  C C   . GLY C 1 26  ? 29.022  31.103  11.676  1.00 50.82  ? 26  GLY C C   1 
ATOM   7385  O O   . GLY C 1 26  ? 28.719  30.803  10.519  1.00 46.62  ? 26  GLY C O   1 
ATOM   7386  N N   . ASN C 1 27  ? 29.781  32.162  11.967  1.00 53.16  ? 27  ASN C N   1 
ATOM   7387  C CA  . ASN C 1 27  ? 30.079  33.176  10.967  1.00 64.67  ? 27  ASN C CA  1 
ATOM   7388  C C   . ASN C 1 27  ? 31.399  32.884  10.255  1.00 54.94  ? 27  ASN C C   1 
ATOM   7389  O O   . ASN C 1 27  ? 31.760  33.625  9.349   1.00 54.73  ? 27  ASN C O   1 
ATOM   7390  C CB  . ASN C 1 27  ? 30.101  34.593  11.555  1.00 78.50  ? 27  ASN C CB  1 
ATOM   7391  C CG  . ASN C 1 27  ? 31.103  34.801  12.680  1.00 82.66  ? 27  ASN C CG  1 
ATOM   7392  O OD1 . ASN C 1 27  ? 31.905  33.923  13.012  1.00 78.89  ? 27  ASN C OD1 1 
ATOM   7393  N ND2 . ASN C 1 27  ? 31.052  35.976  13.287  1.00 83.92  ? 27  ASN C ND2 1 
ATOM   7394  N N   . ARG C 1 28  ? 32.084  31.804  10.653  1.00 52.57  ? 28  ARG C N   1 
ATOM   7395  C CA  . ARG C 1 28  ? 33.319  31.380  10.012  1.00 55.38  ? 28  ARG C CA  1 
ATOM   7396  C C   . ARG C 1 28  ? 33.045  30.814  8.612   1.00 59.98  ? 28  ARG C C   1 
ATOM   7397  O O   . ARG C 1 28  ? 32.200  29.932  8.429   1.00 57.88  ? 28  ARG C O   1 
ATOM   7398  C CB  . ARG C 1 28  ? 34.044  30.358  10.890  1.00 52.97  ? 28  ARG C CB  1 
ATOM   7399  C CG  . ARG C 1 28  ? 34.466  30.886  12.256  1.00 61.41  ? 28  ARG C CG  1 
ATOM   7400  C CD  . ARG C 1 28  ? 35.507  32.007  12.180  1.00 70.20  ? 28  ARG C CD  1 
ATOM   7401  N NE  . ARG C 1 28  ? 36.234  32.283  13.420  1.00 68.84  ? 28  ARG C NE  1 
ATOM   7402  C CZ  . ARG C 1 28  ? 35.693  32.823  14.515  1.00 79.71  ? 28  ARG C CZ  1 
ATOM   7403  N NH1 . ARG C 1 28  ? 34.420  33.191  14.535  1.00 87.05  ? 28  ARG C NH1 1 
ATOM   7404  N NH2 . ARG C 1 28  ? 36.428  32.999  15.597  1.00 81.70  ? 28  ARG C NH2 1 
ATOM   7405  N N   . LYS C 1 29  ? 33.797  31.326  7.630   1.00 54.24  ? 29  LYS C N   1 
ATOM   7406  C CA  . LYS C 1 29  ? 33.667  30.924  6.240   1.00 58.81  ? 29  LYS C CA  1 
ATOM   7407  C C   . LYS C 1 29  ? 34.470  29.652  6.007   1.00 59.37  ? 29  LYS C C   1 
ATOM   7408  O O   . LYS C 1 29  ? 35.584  29.517  6.499   1.00 60.26  ? 29  LYS C O   1 
ATOM   7409  C CB  . LYS C 1 29  ? 34.124  32.051  5.314   1.00 57.08  ? 29  LYS C CB  1 
ATOM   7410  C CG  . LYS C 1 29  ? 34.420  31.652  3.878   1.00 62.36  ? 29  LYS C CG  1 
ATOM   7411  C CD  . LYS C 1 29  ? 34.886  32.824  3.049   1.00 62.07  ? 29  LYS C CD  1 
ATOM   7412  C CE  . LYS C 1 29  ? 35.218  32.432  1.631   1.00 65.65  ? 29  LYS C CE  1 
ATOM   7413  N NZ  . LYS C 1 29  ? 35.884  33.535  0.902   1.00 74.10  ? 29  LYS C NZ  1 
ATOM   7414  N N   . THR C 1 30  ? 33.860  28.702  5.295   1.00 57.90  ? 30  THR C N   1 
ATOM   7415  C CA  . THR C 1 30  ? 34.528  27.460  4.943   1.00 53.80  ? 30  THR C CA  1 
ATOM   7416  C C   . THR C 1 30  ? 34.938  27.505  3.482   1.00 47.37  ? 30  THR C C   1 
ATOM   7417  O O   . THR C 1 30  ? 35.907  26.843  3.140   1.00 51.37  ? 30  THR C O   1 
ATOM   7418  C CB  . THR C 1 30  ? 33.647  26.213  5.103   1.00 47.48  ? 30  THR C CB  1 
ATOM   7419  O OG1 . THR C 1 30  ? 32.441  26.498  4.390   1.00 47.91  ? 30  THR C OG1 1 
ATOM   7420  C CG2 . THR C 1 30  ? 33.375  25.845  6.539   1.00 50.61  ? 30  THR C CG2 1 
ATOM   7421  N N   . MET C 1 31  ? 34.151  28.193  2.631   1.00 42.84  ? 31  MET C N   1 
ATOM   7422  C CA  . MET C 1 31  ? 34.465  28.260  1.211   1.00 40.40  ? 31  MET C CA  1 
ATOM   7423  C C   . MET C 1 31  ? 33.532  29.257  0.561   1.00 47.89  ? 31  MET C C   1 
ATOM   7424  O O   . MET C 1 31  ? 32.669  29.829  1.217   1.00 50.84  ? 31  MET C O   1 
ATOM   7425  C CB  . MET C 1 31  ? 34.294  26.894  0.525   1.00 47.29  ? 31  MET C CB  1 
ATOM   7426  C CG  . MET C 1 31  ? 33.084  26.074  1.017   1.00 57.65  ? 31  MET C CG  1 
ATOM   7427  S SD  . MET C 1 31  ? 32.693  24.484  0.142   1.00 53.15  ? 31  MET C SD  1 
ATOM   7428  C CE  . MET C 1 31  ? 32.604  25.039  -1.561  1.00 53.48  ? 31  MET C CE  1 
ATOM   7429  N N   . ASP C 1 32  ? 33.708  29.450  -0.740  1.00 51.98  ? 32  ASP C N   1 
ATOM   7430  C CA  . ASP C 1 32  ? 32.823  30.298  -1.503  1.00 58.35  ? 32  ASP C CA  1 
ATOM   7431  C C   . ASP C 1 32  ? 31.673  29.455  -2.050  1.00 57.72  ? 32  ASP C C   1 
ATOM   7432  O O   . ASP C 1 32  ? 31.844  28.312  -2.442  1.00 50.41  ? 32  ASP C O   1 
ATOM   7433  C CB  . ASP C 1 32  ? 33.612  31.013  -2.608  1.00 71.19  ? 32  ASP C CB  1 
ATOM   7434  C CG  . ASP C 1 32  ? 34.745  31.882  -2.064  1.00 80.74  ? 32  ASP C CG  1 
ATOM   7435  O OD1 . ASP C 1 32  ? 34.443  32.804  -1.248  1.00 72.96  ? 32  ASP C OD1 1 
ATOM   7436  O OD2 . ASP C 1 32  ? 35.924  31.631  -2.439  1.00 71.97  ? 32  ASP C OD2 1 
ATOM   7437  N N   . CYS C 1 33  ? 30.491  30.048  -2.105  1.00 57.65  ? 33  CYS C N   1 
ATOM   7438  C CA  . CYS C 1 33  ? 29.383  29.433  -2.795  1.00 57.84  ? 33  CYS C CA  1 
ATOM   7439  C C   . CYS C 1 33  ? 29.286  30.078  -4.167  1.00 54.03  ? 33  CYS C C   1 
ATOM   7440  O O   . CYS C 1 33  ? 29.421  31.283  -4.298  1.00 60.94  ? 33  CYS C O   1 
ATOM   7441  C CB  . CYS C 1 33  ? 28.106  29.608  -1.979  1.00 59.74  ? 33  CYS C CB  1 
ATOM   7442  S SG  . CYS C 1 33  ? 26.650  28.833  -2.720  1.00 57.19  ? 33  CYS C SG  1 
ATOM   7443  N N   . THR C 1 34  ? 29.009  29.273  -5.186  1.00 54.92  ? 34  THR C N   1 
ATOM   7444  C CA  . THR C 1 34  ? 29.159  29.729  -6.551  1.00 55.81  ? 34  THR C CA  1 
ATOM   7445  C C   . THR C 1 34  ? 27.921  29.411  -7.372  1.00 49.42  ? 34  THR C C   1 
ATOM   7446  O O   . THR C 1 34  ? 27.105  28.579  -7.008  1.00 55.35  ? 34  THR C O   1 
ATOM   7447  C CB  . THR C 1 34  ? 30.364  29.063  -7.224  1.00 54.60  ? 34  THR C CB  1 
ATOM   7448  O OG1 . THR C 1 34  ? 29.915  27.753  -7.565  1.00 48.64  ? 34  THR C OG1 1 
ATOM   7449  C CG2 . THR C 1 34  ? 31.588  29.011  -6.331  1.00 51.78  ? 34  THR C CG2 1 
ATOM   7450  N N   . ILE C 1 35  ? 27.835  30.071  -8.519  1.00 52.71  ? 35  ILE C N   1 
ATOM   7451  C CA  . ILE C 1 35  ? 26.746  29.859  -9.451  1.00 53.15  ? 35  ILE C CA  1 
ATOM   7452  C C   . ILE C 1 35  ? 26.803  28.423  -9.954  1.00 49.63  ? 35  ILE C C   1 
ATOM   7453  O O   . ILE C 1 35  ? 25.760  27.847  -10.207 1.00 50.15  ? 35  ILE C O   1 
ATOM   7454  C CB  . ILE C 1 35  ? 26.801  30.897  -10.584 1.00 45.48  ? 35  ILE C CB  1 
ATOM   7455  C CG1 . ILE C 1 35  ? 26.234  32.232  -10.092 1.00 51.36  ? 35  ILE C CG1 1 
ATOM   7456  C CG2 . ILE C 1 35  ? 26.113  30.377  -11.825 1.00 43.34  ? 35  ILE C CG2 1 
ATOM   7457  C CD1 . ILE C 1 35  ? 25.608  33.079  -11.169 1.00 61.70  ? 35  ILE C CD1 1 
ATOM   7458  N N   . GLY C 1 36  ? 28.008  27.853  -10.064 1.00 45.49  ? 36  GLY C N   1 
ATOM   7459  C CA  . GLY C 1 36  ? 28.172  26.470  -10.502 1.00 45.90  ? 36  GLY C CA  1 
ATOM   7460  C C   . GLY C 1 36  ? 27.688  25.455  -9.463  1.00 46.82  ? 36  GLY C C   1 
ATOM   7461  O O   . GLY C 1 36  ? 27.353  24.326  -9.807  1.00 45.08  ? 36  GLY C O   1 
ATOM   7462  N N   . HIS C 1 37  ? 27.722  25.842  -8.186  1.00 45.19  ? 37  HIS C N   1 
ATOM   7463  C CA  . HIS C 1 37  ? 27.192  25.025  -7.101  1.00 47.46  ? 37  HIS C CA  1 
ATOM   7464  C C   . HIS C 1 37  ? 25.674  24.848  -7.208  1.00 49.93  ? 37  HIS C C   1 
ATOM   7465  O O   . HIS C 1 37  ? 25.166  23.740  -7.048  1.00 52.14  ? 37  HIS C O   1 
ATOM   7466  C CB  . HIS C 1 37  ? 27.528  25.652  -5.756  1.00 46.59  ? 37  HIS C CB  1 
ATOM   7467  C CG  . HIS C 1 37  ? 28.904  25.360  -5.288  1.00 51.64  ? 37  HIS C CG  1 
ATOM   7468  N ND1 . HIS C 1 37  ? 29.777  26.334  -4.857  1.00 53.05  ? 37  HIS C ND1 1 
ATOM   7469  C CD2 . HIS C 1 37  ? 29.536  24.196  -5.143  1.00 51.85  ? 37  HIS C CD2 1 
ATOM   7470  C CE1 . HIS C 1 37  ? 30.899  25.753  -4.450  1.00 57.19  ? 37  HIS C CE1 1 
ATOM   7471  N NE2 . HIS C 1 37  ? 30.779  24.455  -4.620  1.00 52.03  ? 37  HIS C NE2 1 
ATOM   7472  N N   . ALA C 1 38  ? 24.986  25.943  -7.533  1.00 47.31  ? 38  ALA C N   1 
ATOM   7473  C CA  . ALA C 1 38  ? 23.543  25.991  -7.610  1.00 50.48  ? 38  ALA C CA  1 
ATOM   7474  C C   . ALA C 1 38  ? 23.020  25.206  -8.807  1.00 56.72  ? 38  ALA C C   1 
ATOM   7475  O O   . ALA C 1 38  ? 21.949  24.597  -8.699  1.00 57.75  ? 38  ALA C O   1 
ATOM   7476  C CB  . ALA C 1 38  ? 23.114  27.434  -7.675  1.00 51.24  ? 38  ALA C CB  1 
ATOM   7477  N N   . TYR C 1 39  ? 23.745  25.270  -9.936  1.00 48.32  ? 39  TYR C N   1 
ATOM   7478  C CA  . TYR C 1 39  ? 23.384  24.583  -11.167 1.00 47.04  ? 39  TYR C CA  1 
ATOM   7479  C C   . TYR C 1 39  ? 24.122  23.247  -11.317 1.00 46.48  ? 39  TYR C C   1 
ATOM   7480  O O   . TYR C 1 39  ? 23.944  22.535  -12.291 1.00 55.93  ? 39  TYR C O   1 
ATOM   7481  C CB  . TYR C 1 39  ? 23.753  25.411  -12.398 1.00 46.19  ? 39  TYR C CB  1 
ATOM   7482  C CG  . TYR C 1 39  ? 22.830  26.550  -12.731 1.00 47.85  ? 39  TYR C CG  1 
ATOM   7483  C CD1 . TYR C 1 39  ? 22.984  27.794  -12.135 1.00 52.35  ? 39  TYR C CD1 1 
ATOM   7484  C CD2 . TYR C 1 39  ? 21.831  26.400  -13.677 1.00 42.00  ? 39  TYR C CD2 1 
ATOM   7485  C CE1 . TYR C 1 39  ? 22.150  28.858  -12.448 1.00 48.16  ? 39  TYR C CE1 1 
ATOM   7486  C CE2 . TYR C 1 39  ? 20.988  27.451  -13.998 1.00 47.33  ? 39  TYR C CE2 1 
ATOM   7487  C CZ  . TYR C 1 39  ? 21.145  28.685  -13.379 1.00 50.70  ? 39  TYR C CZ  1 
ATOM   7488  O OH  . TYR C 1 39  ? 20.283  29.720  -13.661 1.00 48.90  ? 39  TYR C OH  1 
ATOM   7489  N N   . GLY C 1 40  ? 24.974  22.902  -10.364 1.00 48.19  ? 40  GLY C N   1 
ATOM   7490  C CA  . GLY C 1 40  ? 25.776  21.700  -10.468 1.00 45.51  ? 40  GLY C CA  1 
ATOM   7491  C C   . GLY C 1 40  ? 25.498  20.756  -9.311  1.00 41.50  ? 40  GLY C C   1 
ATOM   7492  O O   . GLY C 1 40  ? 26.387  20.049  -8.864  1.00 42.89  ? 40  GLY C O   1 
ATOM   7493  N N   . GLY C 1 41  ? 24.254  20.781  -8.828  1.00 47.67  ? 41  GLY C N   1 
ATOM   7494  C CA  . GLY C 1 41  ? 23.834  19.940  -7.713  1.00 44.46  ? 41  GLY C CA  1 
ATOM   7495  C C   . GLY C 1 41  ? 24.739  20.006  -6.490  1.00 41.11  ? 41  GLY C C   1 
ATOM   7496  O O   . GLY C 1 41  ? 24.992  18.971  -5.902  1.00 43.95  ? 41  GLY C O   1 
ATOM   7497  N N   . MET C 1 42  ? 25.281  21.189  -6.162  1.00 45.13  ? 42  MET C N   1 
ATOM   7498  C CA  . MET C 1 42  ? 25.972  21.449  -4.899  1.00 43.41  ? 42  MET C CA  1 
ATOM   7499  C C   . MET C 1 42  ? 27.330  20.740  -4.768  1.00 42.54  ? 42  MET C C   1 
ATOM   7500  O O   . MET C 1 42  ? 27.848  20.530  -3.645  1.00 39.80  ? 42  MET C O   1 
ATOM   7501  C CB  . MET C 1 42  ? 25.103  21.032  -3.706  1.00 48.40  ? 42  MET C CB  1 
ATOM   7502  C CG  . MET C 1 42  ? 23.814  21.815  -3.550  1.00 54.46  ? 42  MET C CG  1 
ATOM   7503  S SD  . MET C 1 42  ? 22.993  21.480  -1.940  1.00 55.25  ? 42  MET C SD  1 
ATOM   7504  C CE  . MET C 1 42  ? 21.304  21.858  -2.398  1.00 60.99  ? 42  MET C CE  1 
ATOM   7505  N N   . ARG C 1 43  ? 27.941  20.331  -5.884  1.00 45.94  ? 43  ARG C N   1 
ATOM   7506  C CA  . ARG C 1 43  ? 29.134  19.497  -5.766  1.00 49.73  ? 43  ARG C CA  1 
ATOM   7507  C C   . ARG C 1 43  ? 30.214  20.209  -4.923  1.00 49.34  ? 43  ARG C C   1 
ATOM   7508  O O   . ARG C 1 43  ? 30.630  21.318  -5.205  1.00 44.92  ? 43  ARG C O   1 
ATOM   7509  C CB  . ARG C 1 43  ? 29.621  19.126  -7.163  1.00 54.51  ? 43  ARG C CB  1 
ATOM   7510  C CG  . ARG C 1 43  ? 30.773  18.136  -7.160  1.00 74.34  ? 43  ARG C CG  1 
ATOM   7511  C CD  . ARG C 1 43  ? 31.638  18.271  -8.410  1.00 83.95  ? 43  ARG C CD  1 
ATOM   7512  N NE  . ARG C 1 43  ? 31.082  17.547  -9.541  1.00 85.52  ? 43  ARG C NE  1 
ATOM   7513  C CZ  . ARG C 1 43  ? 31.134  16.226  -9.694  1.00 90.16  ? 43  ARG C CZ  1 
ATOM   7514  N NH1 . ARG C 1 43  ? 31.837  15.480  -8.856  1.00 93.99  ? 43  ARG C NH1 1 
ATOM   7515  N NH2 . ARG C 1 43  ? 30.503  15.658  -10.708 1.00 86.04  ? 43  ARG C NH2 1 
ATOM   7516  N N   . GLY C 1 44  ? 30.662  19.573  -3.847  1.00 50.07  ? 44  GLY C N   1 
ATOM   7517  C CA  . GLY C 1 44  ? 31.708  20.111  -2.986  1.00 45.83  ? 44  GLY C CA  1 
ATOM   7518  C C   . GLY C 1 44  ? 31.191  21.180  -2.018  1.00 45.77  ? 44  GLY C C   1 
ATOM   7519  O O   . GLY C 1 44  ? 31.940  21.708  -1.212  1.00 38.97  ? 44  GLY C O   1 
ATOM   7520  N N   . LEU C 1 45  ? 29.906  21.523  -2.086  1.00 50.27  ? 45  LEU C N   1 
ATOM   7521  C CA  . LEU C 1 45  ? 29.420  22.590  -1.235  1.00 46.68  ? 45  LEU C CA  1 
ATOM   7522  C C   . LEU C 1 45  ? 29.175  22.013  0.150   1.00 47.68  ? 45  LEU C C   1 
ATOM   7523  O O   . LEU C 1 45  ? 28.403  21.088  0.286   1.00 51.94  ? 45  LEU C O   1 
ATOM   7524  C CB  . LEU C 1 45  ? 28.178  23.223  -1.843  1.00 43.99  ? 45  LEU C CB  1 
ATOM   7525  C CG  . LEU C 1 45  ? 27.600  24.401  -1.061  1.00 46.57  ? 45  LEU C CG  1 
ATOM   7526  C CD1 . LEU C 1 45  ? 28.582  25.539  -1.012  1.00 51.72  ? 45  LEU C CD1 1 
ATOM   7527  C CD2 . LEU C 1 45  ? 26.296  24.855  -1.675  1.00 48.12  ? 45  LEU C CD2 1 
ATOM   7528  N N   . LYS C 1 46  ? 29.869  22.566  1.148   1.00 50.83  ? 46  LYS C N   1 
ATOM   7529  C CA  . LYS C 1 46  ? 29.928  22.021  2.491   1.00 52.02  ? 46  LYS C CA  1 
ATOM   7530  C C   . LYS C 1 46  ? 28.697  22.426  3.296   1.00 51.53  ? 46  LYS C C   1 
ATOM   7531  O O   . LYS C 1 46  ? 28.823  23.081  4.326   1.00 56.96  ? 46  LYS C O   1 
ATOM   7532  C CB  . LYS C 1 46  ? 31.208  22.519  3.167   1.00 52.39  ? 46  LYS C CB  1 
ATOM   7533  C CG  . LYS C 1 46  ? 32.478  21.758  2.784   1.00 56.34  ? 46  LYS C CG  1 
ATOM   7534  C CD  . LYS C 1 46  ? 33.723  22.409  3.354   1.00 56.13  ? 46  LYS C CD  1 
ATOM   7535  C CE  . LYS C 1 46  ? 34.915  21.483  3.519   1.00 65.72  ? 46  LYS C CE  1 
ATOM   7536  N NZ  . LYS C 1 46  ? 35.876  21.602  2.404   1.00 67.82  ? 46  LYS C NZ  1 
ATOM   7537  N N   . ALA C 1 47  ? 27.517  21.953  2.878   1.00 51.88  ? 47  ALA C N   1 
ATOM   7538  C CA  . ALA C 1 47  ? 26.264  22.512  3.360   1.00 52.25  ? 47  ALA C CA  1 
ATOM   7539  C C   . ALA C 1 47  ? 25.527  21.638  4.385   1.00 44.65  ? 47  ALA C C   1 
ATOM   7540  O O   . ALA C 1 47  ? 24.427  22.010  4.749   1.00 50.10  ? 47  ALA C O   1 
ATOM   7541  C CB  . ALA C 1 47  ? 25.399  22.832  2.166   1.00 52.73  ? 47  ALA C CB  1 
ATOM   7542  N N   . LEU C 1 48  ? 26.135  20.550  4.897   1.00 45.26  ? 48  LEU C N   1 
ATOM   7543  C CA  . LEU C 1 48  ? 25.496  19.557  5.761   1.00 41.39  ? 48  LEU C CA  1 
ATOM   7544  C C   . LEU C 1 48  ? 26.477  19.101  6.841   1.00 39.99  ? 48  LEU C C   1 
ATOM   7545  O O   . LEU C 1 48  ? 27.665  19.054  6.567   1.00 43.43  ? 48  LEU C O   1 
ATOM   7546  C CB  . LEU C 1 48  ? 25.198  18.291  4.943   1.00 50.31  ? 48  LEU C CB  1 
ATOM   7547  C CG  . LEU C 1 48  ? 23.947  18.249  4.080   1.00 60.49  ? 48  LEU C CG  1 
ATOM   7548  C CD1 . LEU C 1 48  ? 23.944  16.960  3.290   1.00 62.66  ? 48  LEU C CD1 1 
ATOM   7549  C CD2 . LEU C 1 48  ? 22.686  18.341  4.928   1.00 58.06  ? 48  LEU C CD2 1 
ATOM   7550  N N   . VAL C 1 49  ? 25.957  18.578  7.963   1.00 42.34  ? 49  VAL C N   1 
ATOM   7551  C CA  . VAL C 1 49  ? 26.726  17.938  9.017   1.00 44.75  ? 49  VAL C CA  1 
ATOM   7552  C C   . VAL C 1 49  ? 26.378  16.446  9.158   1.00 42.83  ? 49  VAL C C   1 
ATOM   7553  O O   . VAL C 1 49  ? 25.237  16.046  9.049   1.00 42.66  ? 49  VAL C O   1 
ATOM   7554  C CB  . VAL C 1 49  ? 26.483  18.685  10.343  1.00 46.89  ? 49  VAL C CB  1 
ATOM   7555  C CG1 . VAL C 1 49  ? 26.986  17.909  11.534  1.00 45.36  ? 49  VAL C CG1 1 
ATOM   7556  C CG2 . VAL C 1 49  ? 27.137  20.061  10.328  1.00 51.88  ? 49  VAL C CG2 1 
ATOM   7557  N N   . CYS C 1 50  ? 27.386  15.636  9.506   1.00 45.77  ? 50  CYS C N   1 
ATOM   7558  C CA  . CYS C 1 50  ? 27.307  14.186  9.642   1.00 40.58  ? 50  CYS C CA  1 
ATOM   7559  C C   . CYS C 1 50  ? 28.523  13.685  10.412  1.00 41.73  ? 50  CYS C C   1 
ATOM   7560  O O   . CYS C 1 50  ? 29.654  13.880  9.966   1.00 46.08  ? 50  CYS C O   1 
ATOM   7561  C CB  . CYS C 1 50  ? 27.288  13.472  8.292   1.00 40.27  ? 50  CYS C CB  1 
ATOM   7562  S SG  . CYS C 1 50  ? 27.326  11.668  8.450   1.00 51.01  ? 50  CYS C SG  1 
ATOM   7563  N N   . ASP C 1 51  ? 28.277  13.065  11.565  1.00 39.12  ? 51  ASP C N   1 
ATOM   7564  C CA  . ASP C 1 51  ? 29.326  12.626  12.461  1.00 45.51  ? 51  ASP C CA  1 
ATOM   7565  C C   . ASP C 1 51  ? 29.425  11.108  12.444  1.00 45.98  ? 51  ASP C C   1 
ATOM   7566  O O   . ASP C 1 51  ? 30.329  10.550  13.037  1.00 44.92  ? 51  ASP C O   1 
ATOM   7567  C CB  . ASP C 1 51  ? 29.102  13.171  13.875  1.00 53.79  ? 51  ASP C CB  1 
ATOM   7568  C CG  . ASP C 1 51  ? 29.295  14.682  13.938  1.00 55.73  ? 51  ASP C CG  1 
ATOM   7569  O OD1 . ASP C 1 51  ? 30.123  15.184  13.163  1.00 48.83  ? 51  ASP C OD1 1 
ATOM   7570  O OD2 . ASP C 1 51  ? 28.631  15.342  14.758  1.00 55.54  ? 51  ASP C OD2 1 
ATOM   7571  N N   . THR C 1 52  ? 28.550  10.427  11.707  1.00 45.89  ? 52  THR C N   1 
ATOM   7572  C CA  . THR C 1 52  ? 28.616  8.973   11.690  1.00 44.49  ? 52  THR C CA  1 
ATOM   7573  C C   . THR C 1 52  ? 29.818  8.490   10.882  1.00 42.19  ? 52  THR C C   1 
ATOM   7574  O O   . THR C 1 52  ? 30.437  7.501   11.246  1.00 42.00  ? 52  THR C O   1 
ATOM   7575  C CB  . THR C 1 52  ? 27.319  8.370   11.155  1.00 41.27  ? 52  THR C CB  1 
ATOM   7576  O OG1 . THR C 1 52  ? 27.038  8.968   9.885   1.00 40.09  ? 52  THR C OG1 1 
ATOM   7577  C CG2 . THR C 1 52  ? 26.176  8.592   12.124  1.00 47.33  ? 52  THR C CG2 1 
ATOM   7578  N N   . SER C 1 53  ? 30.084  9.155   9.756   1.00 41.01  ? 53  SER C N   1 
ATOM   7579  C CA  . SER C 1 53  ? 31.088  8.698   8.812   1.00 46.58  ? 53  SER C CA  1 
ATOM   7580  C C   . SER C 1 53  ? 31.611  9.893   8.016   1.00 43.97  ? 53  SER C C   1 
ATOM   7581  O O   . SER C 1 53  ? 30.951  10.925  7.915   1.00 44.28  ? 53  SER C O   1 
ATOM   7582  C CB  . SER C 1 53  ? 30.535  7.618   7.878   1.00 41.02  ? 53  SER C CB  1 
ATOM   7583  O OG  . SER C 1 53  ? 29.681  8.180   6.873   1.00 41.92  ? 53  SER C OG  1 
ATOM   7584  N N   . GLU C 1 54  ? 32.797  9.719   7.434   1.00 44.06  ? 54  GLU C N   1 
ATOM   7585  C CA  . GLU C 1 54  ? 33.424  10.767  6.650   1.00 44.42  ? 54  GLU C CA  1 
ATOM   7586  C C   . GLU C 1 54  ? 34.209  10.114  5.514   1.00 39.94  ? 54  GLU C C   1 
ATOM   7587  O O   . GLU C 1 54  ? 34.896  9.136   5.739   1.00 48.04  ? 54  GLU C O   1 
ATOM   7588  C CB  . GLU C 1 54  ? 34.325  11.588  7.582   1.00 48.37  ? 54  GLU C CB  1 
ATOM   7589  C CG  . GLU C 1 54  ? 34.999  12.792  6.917   1.00 58.85  ? 54  GLU C CG  1 
ATOM   7590  C CD  . GLU C 1 54  ? 35.911  13.649  7.791   1.00 56.40  ? 54  GLU C CD  1 
ATOM   7591  O OE1 . GLU C 1 54  ? 36.451  14.648  7.254   1.00 67.42  ? 54  GLU C OE1 1 
ATOM   7592  O OE2 . GLU C 1 54  ? 36.086  13.321  8.999   1.00 54.10  ? 54  GLU C OE2 1 
ATOM   7593  N N   . VAL C 1 55  ? 34.122  10.666  4.306   1.00 42.83  ? 55  VAL C N   1 
ATOM   7594  C CA  . VAL C 1 55  ? 34.800  10.101  3.154   1.00 48.30  ? 55  VAL C CA  1 
ATOM   7595  C C   . VAL C 1 55  ? 35.988  11.003  2.808   1.00 53.84  ? 55  VAL C C   1 
ATOM   7596  O O   . VAL C 1 55  ? 35.819  12.168  2.424   1.00 54.08  ? 55  VAL C O   1 
ATOM   7597  C CB  . VAL C 1 55  ? 33.849  9.941   1.952   1.00 53.07  ? 55  VAL C CB  1 
ATOM   7598  C CG1 . VAL C 1 55  ? 34.576  9.426   0.725   1.00 56.23  ? 55  VAL C CG1 1 
ATOM   7599  C CG2 . VAL C 1 55  ? 32.654  9.058   2.264   1.00 55.89  ? 55  VAL C CG2 1 
ATOM   7600  N N   . PHE C 1 56  ? 37.190  10.438  2.976   1.00 53.52  ? 56  PHE C N   1 
ATOM   7601  C CA  . PHE C 1 56  ? 38.436  11.084  2.613   1.00 55.05  ? 56  PHE C CA  1 
ATOM   7602  C C   . PHE C 1 56  ? 38.782  10.735  1.173   1.00 57.08  ? 56  PHE C C   1 
ATOM   7603  O O   . PHE C 1 56  ? 38.904  9.552   0.858   1.00 59.61  ? 56  PHE C O   1 
ATOM   7604  C CB  . PHE C 1 56  ? 39.545  10.605  3.544   1.00 51.08  ? 56  PHE C CB  1 
ATOM   7605  C CG  . PHE C 1 56  ? 39.376  11.073  4.963   1.00 51.86  ? 56  PHE C CG  1 
ATOM   7606  C CD1 . PHE C 1 56  ? 38.616  10.344  5.869   1.00 51.62  ? 56  PHE C CD1 1 
ATOM   7607  C CD2 . PHE C 1 56  ? 39.946  12.263  5.382   1.00 55.51  ? 56  PHE C CD2 1 
ATOM   7608  C CE1 . PHE C 1 56  ? 38.473  10.769  7.181   1.00 50.80  ? 56  PHE C CE1 1 
ATOM   7609  C CE2 . PHE C 1 56  ? 39.786  12.696  6.692   1.00 61.92  ? 56  PHE C CE2 1 
ATOM   7610  C CZ  . PHE C 1 56  ? 39.049  11.949  7.589   1.00 58.02  ? 56  PHE C CZ  1 
ATOM   7611  N N   . PRO C 1 57  ? 38.869  11.718  0.246   1.00 62.26  ? 57  PRO C N   1 
ATOM   7612  C CA  . PRO C 1 57  ? 39.179  11.420  -1.160  1.00 60.53  ? 57  PRO C CA  1 
ATOM   7613  C C   . PRO C 1 57  ? 40.414  10.547  -1.397  1.00 59.71  ? 57  PRO C C   1 
ATOM   7614  O O   . PRO C 1 57  ? 40.493  9.884   -2.430  1.00 68.23  ? 57  PRO C O   1 
ATOM   7615  C CB  . PRO C 1 57  ? 39.359  12.811  -1.789  1.00 61.80  ? 57  PRO C CB  1 
ATOM   7616  C CG  . PRO C 1 57  ? 38.459  13.716  -0.941  1.00 65.08  ? 57  PRO C CG  1 
ATOM   7617  C CD  . PRO C 1 57  ? 38.567  13.149  0.467   1.00 62.91  ? 57  PRO C CD  1 
ATOM   7618  N N   . ASP C 1 58  ? 41.346  10.519  -0.431  1.00 57.27  ? 58  ASP C N   1 
ATOM   7619  C CA  . ASP C 1 58  ? 42.612  9.822   -0.589  1.00 64.33  ? 58  ASP C CA  1 
ATOM   7620  C C   . ASP C 1 58  ? 42.666  8.547   0.252   1.00 62.51  ? 58  ASP C C   1 
ATOM   7621  O O   . ASP C 1 58  ? 43.635  7.803   0.117   1.00 66.63  ? 58  ASP C O   1 
ATOM   7622  C CB  . ASP C 1 58  ? 43.818  10.702  -0.216  1.00 73.89  ? 58  ASP C CB  1 
ATOM   7623  C CG  . ASP C 1 58  ? 44.203  11.819  -1.194  1.00 79.26  ? 58  ASP C CG  1 
ATOM   7624  O OD1 . ASP C 1 58  ? 43.401  12.162  -2.086  1.00 68.44  ? 58  ASP C OD1 1 
ATOM   7625  O OD2 . ASP C 1 58  ? 45.328  12.359  -1.055  1.00 85.31  ? 58  ASP C OD2 1 
ATOM   7626  N N   . GLU C 1 59  ? 41.675  8.294   1.125   1.00 54.41  ? 59  GLU C N   1 
ATOM   7627  C CA  . GLU C 1 59  ? 41.639  7.053   1.897   1.00 56.23  ? 59  GLU C CA  1 
ATOM   7628  C C   . GLU C 1 59  ? 40.281  6.335   1.839   1.00 47.39  ? 59  GLU C C   1 
ATOM   7629  O O   . GLU C 1 59  ? 40.185  5.183   2.262   1.00 47.99  ? 59  GLU C O   1 
ATOM   7630  C CB  . GLU C 1 59  ? 41.917  7.283   3.384   1.00 57.91  ? 59  GLU C CB  1 
ATOM   7631  C CG  . GLU C 1 59  ? 43.134  8.114   3.715   1.00 59.04  ? 59  GLU C CG  1 
ATOM   7632  C CD  . GLU C 1 59  ? 43.248  8.361   5.215   1.00 58.15  ? 59  GLU C CD  1 
ATOM   7633  O OE1 . GLU C 1 59  ? 43.240  7.359   5.971   1.00 57.73  ? 59  GLU C OE1 1 
ATOM   7634  O OE2 . GLU C 1 59  ? 43.331  9.546   5.627   1.00 53.62  ? 59  GLU C OE2 1 
ATOM   7635  N N   . GLY C 1 60  ? 39.223  7.026   1.392   1.00 53.75  ? 60  GLY C N   1 
ATOM   7636  C CA  . GLY C 1 60  ? 37.862  6.491   1.425   1.00 58.50  ? 60  GLY C CA  1 
ATOM   7637  C C   . GLY C 1 60  ? 37.183  6.675   2.787   1.00 57.81  ? 60  GLY C C   1 
ATOM   7638  O O   . GLY C 1 60  ? 37.487  7.620   3.523   1.00 53.82  ? 60  GLY C O   1 
ATOM   7639  N N   . VAL C 1 61  ? 36.250  5.773   3.116   1.00 49.66  ? 61  VAL C N   1 
ATOM   7640  C CA  . VAL C 1 61  ? 35.267  6.094   4.132   1.00 44.18  ? 61  VAL C CA  1 
ATOM   7641  C C   . VAL C 1 61  ? 35.816  5.685   5.491   1.00 38.91  ? 61  VAL C C   1 
ATOM   7642  O O   . VAL C 1 61  ? 36.363  4.599   5.651   1.00 43.06  ? 61  VAL C O   1 
ATOM   7643  C CB  . VAL C 1 61  ? 33.881  5.471   3.837   1.00 44.97  ? 61  VAL C CB  1 
ATOM   7644  C CG1 . VAL C 1 61  ? 33.824  3.971   4.028   1.00 40.97  ? 61  VAL C CG1 1 
ATOM   7645  C CG2 . VAL C 1 61  ? 32.800  6.119   4.684   1.00 47.18  ? 61  VAL C CG2 1 
ATOM   7646  N N   . LYS C 1 62  ? 35.627  6.540   6.487   1.00 41.53  ? 62  LYS C N   1 
ATOM   7647  C CA  . LYS C 1 62  ? 35.843  6.109   7.860   1.00 43.80  ? 62  LYS C CA  1 
ATOM   7648  C C   . LYS C 1 62  ? 34.549  6.206   8.648   1.00 39.79  ? 62  LYS C C   1 
ATOM   7649  O O   . LYS C 1 62  ? 33.793  7.147   8.482   1.00 44.90  ? 62  LYS C O   1 
ATOM   7650  C CB  . LYS C 1 62  ? 36.925  6.956   8.515   1.00 48.62  ? 62  LYS C CB  1 
ATOM   7651  C CG  . LYS C 1 62  ? 38.259  6.951   7.786   1.00 48.67  ? 62  LYS C CG  1 
ATOM   7652  C CD  . LYS C 1 62  ? 39.356  7.619   8.590   1.00 55.89  ? 62  LYS C CD  1 
ATOM   7653  C CE  . LYS C 1 62  ? 40.681  7.660   7.851   1.00 60.75  ? 62  LYS C CE  1 
ATOM   7654  N NZ  . LYS C 1 62  ? 41.709  8.281   8.708   1.00 63.23  ? 62  LYS C NZ  1 
ATOM   7655  N N   . PHE C 1 63  ? 34.343  5.207   9.504   1.00 40.04  ? 63  PHE C N   1 
ATOM   7656  C CA  . PHE C 1 63  ? 33.223  5.116   10.405  1.00 39.41  ? 63  PHE C CA  1 
ATOM   7657  C C   . PHE C 1 63  ? 33.655  5.600   11.790  1.00 38.50  ? 63  PHE C C   1 
ATOM   7658  O O   . PHE C 1 63  ? 34.349  4.894   12.503  1.00 43.63  ? 63  PHE C O   1 
ATOM   7659  C CB  . PHE C 1 63  ? 32.732  3.664   10.416  1.00 42.03  ? 63  PHE C CB  1 
ATOM   7660  C CG  . PHE C 1 63  ? 32.229  3.132   9.099   1.00 41.84  ? 63  PHE C CG  1 
ATOM   7661  C CD1 . PHE C 1 63  ? 31.393  3.892   8.292   1.00 43.35  ? 63  PHE C CD1 1 
ATOM   7662  C CD2 . PHE C 1 63  ? 32.502  1.834   8.707   1.00 47.50  ? 63  PHE C CD2 1 
ATOM   7663  C CE1 . PHE C 1 63  ? 30.926  3.400   7.084   1.00 43.60  ? 63  PHE C CE1 1 
ATOM   7664  C CE2 . PHE C 1 63  ? 32.024  1.340   7.500   1.00 43.35  ? 63  PHE C CE2 1 
ATOM   7665  C CZ  . PHE C 1 63  ? 31.245  2.125   6.689   1.00 40.68  ? 63  PHE C CZ  1 
ATOM   7666  N N   . ARG C 1 64  ? 33.271  6.818   12.149  1.00 37.12  ? 64  ARG C N   1 
ATOM   7667  C CA  . ARG C 1 64  ? 33.631  7.394   13.429  1.00 42.66  ? 64  ARG C CA  1 
ATOM   7668  C C   . ARG C 1 64  ? 35.143  7.305   13.652  1.00 41.19  ? 64  ARG C C   1 
ATOM   7669  O O   . ARG C 1 64  ? 35.580  6.913   14.724  1.00 43.01  ? 64  ARG C O   1 
ATOM   7670  C CB  . ARG C 1 64  ? 32.881  6.690   14.563  1.00 43.15  ? 64  ARG C CB  1 
ATOM   7671  C CG  . ARG C 1 64  ? 31.408  7.034   14.646  1.00 39.95  ? 64  ARG C CG  1 
ATOM   7672  C CD  . ARG C 1 64  ? 31.231  8.480   15.048  1.00 42.02  ? 64  ARG C CD  1 
ATOM   7673  N NE  . ARG C 1 64  ? 29.911  8.636   15.624  1.00 40.02  ? 64  ARG C NE  1 
ATOM   7674  C CZ  . ARG C 1 64  ? 29.435  9.744   16.166  1.00 40.39  ? 64  ARG C CZ  1 
ATOM   7675  N NH1 . ARG C 1 64  ? 30.200  10.808  16.249  1.00 41.59  ? 64  ARG C NH1 1 
ATOM   7676  N NH2 . ARG C 1 64  ? 28.189  9.785   16.630  1.00 45.81  ? 64  ARG C NH2 1 
ATOM   7677  N N   . GLY C 1 65  ? 35.939  7.647   12.623  1.00 47.63  ? 65  GLY C N   1 
ATOM   7678  C CA  . GLY C 1 65  ? 37.390  7.699   12.732  1.00 43.22  ? 65  GLY C CA  1 
ATOM   7679  C C   . GLY C 1 65  ? 38.091  6.390   12.365  1.00 42.00  ? 65  GLY C C   1 
ATOM   7680  O O   . GLY C 1 65  ? 39.313  6.384   12.231  1.00 45.63  ? 65  GLY C O   1 
ATOM   7681  N N   . TYR C 1 66  ? 37.338  5.296   12.181  1.00 41.47  ? 66  TYR C N   1 
ATOM   7682  C CA  . TYR C 1 66  ? 37.932  3.978   11.971  1.00 42.37  ? 66  TYR C CA  1 
ATOM   7683  C C   . TYR C 1 66  ? 37.823  3.554   10.508  1.00 44.01  ? 66  TYR C C   1 
ATOM   7684  O O   . TYR C 1 66  ? 36.820  3.768   9.847   1.00 51.25  ? 66  TYR C O   1 
ATOM   7685  C CB  . TYR C 1 66  ? 37.280  2.916   12.855  1.00 43.73  ? 66  TYR C CB  1 
ATOM   7686  C CG  . TYR C 1 66  ? 37.450  3.118   14.338  1.00 51.73  ? 66  TYR C CG  1 
ATOM   7687  C CD1 . TYR C 1 66  ? 38.611  2.749   14.998  1.00 50.90  ? 66  TYR C CD1 1 
ATOM   7688  C CD2 . TYR C 1 66  ? 36.434  3.669   15.094  1.00 56.15  ? 66  TYR C CD2 1 
ATOM   7689  C CE1 . TYR C 1 66  ? 38.765  2.934   16.367  1.00 49.39  ? 66  TYR C CE1 1 
ATOM   7690  C CE2 . TYR C 1 66  ? 36.578  3.867   16.457  1.00 57.11  ? 66  TYR C CE2 1 
ATOM   7691  C CZ  . TYR C 1 66  ? 37.744  3.503   17.097  1.00 48.91  ? 66  TYR C CZ  1 
ATOM   7692  O OH  . TYR C 1 66  ? 37.827  3.694   18.448  1.00 49.52  ? 66  TYR C OH  1 
ATOM   7693  N N   . THR C 1 67  ? 38.897  2.983   9.980   1.00 50.05  ? 67  THR C N   1 
ATOM   7694  C CA  . THR C 1 67  ? 38.915  2.505   8.612   1.00 46.53  ? 67  THR C CA  1 
ATOM   7695  C C   . THR C 1 67  ? 38.251  1.134   8.587   1.00 52.51  ? 67  THR C C   1 
ATOM   7696  O O   . THR C 1 67  ? 38.151  0.430   9.611   1.00 49.02  ? 67  THR C O   1 
ATOM   7697  C CB  . THR C 1 67  ? 40.348  2.351   8.078   1.00 50.02  ? 67  THR C CB  1 
ATOM   7698  O OG1 . THR C 1 67  ? 40.980  1.316   8.846   1.00 46.47  ? 67  THR C OG1 1 
ATOM   7699  C CG2 . THR C 1 67  ? 41.144  3.633   8.143   1.00 49.75  ? 67  THR C CG2 1 
ATOM   7700  N N   . ILE C 1 68  ? 37.876  0.730   7.382   1.00 40.26  ? 68  ILE C N   1 
ATOM   7701  C CA  . ILE C 1 68  ? 37.228  -0.546  7.242   1.00 46.00  ? 68  ILE C CA  1 
ATOM   7702  C C   . ILE C 1 68  ? 38.182  -1.662  7.674   1.00 44.51  ? 68  ILE C C   1 
ATOM   7703  O O   . ILE C 1 68  ? 37.740  -2.593  8.336   1.00 44.99  ? 68  ILE C O   1 
ATOM   7704  C CB  . ILE C 1 68  ? 36.676  -0.693  5.813   1.00 49.74  ? 68  ILE C CB  1 
ATOM   7705  C CG1 . ILE C 1 68  ? 35.434  0.184   5.651   1.00 51.22  ? 68  ILE C CG1 1 
ATOM   7706  C CG2 . ILE C 1 68  ? 36.419  -2.156  5.465   1.00 51.59  ? 68  ILE C CG2 1 
ATOM   7707  C CD1 . ILE C 1 68  ? 35.045  0.404   4.212   1.00 53.29  ? 68  ILE C CD1 1 
ATOM   7708  N N   . PRO C 1 69  ? 39.490  -1.672  7.304   1.00 49.09  ? 69  PRO C N   1 
ATOM   7709  C CA  . PRO C 1 69  ? 40.440  -2.650  7.859   1.00 44.59  ? 69  PRO C CA  1 
ATOM   7710  C C   . PRO C 1 69  ? 40.531  -2.718  9.376   1.00 39.89  ? 69  PRO C C   1 
ATOM   7711  O O   . PRO C 1 69  ? 40.571  -3.814  9.936   1.00 41.31  ? 69  PRO C O   1 
ATOM   7712  C CB  . PRO C 1 69  ? 41.771  -2.161  7.269   1.00 53.36  ? 69  PRO C CB  1 
ATOM   7713  C CG  . PRO C 1 69  ? 41.354  -1.683  5.894   1.00 52.18  ? 69  PRO C CG  1 
ATOM   7714  C CD  . PRO C 1 69  ? 40.104  -0.885  6.228   1.00 50.80  ? 69  PRO C CD  1 
ATOM   7715  N N   . GLU C 1 70  ? 40.567  -1.559  10.045  1.00 41.55  ? 70  GLU C N   1 
ATOM   7716  C CA  . GLU C 1 70  ? 40.613  -1.546  11.500  1.00 43.45  ? 70  GLU C CA  1 
ATOM   7717  C C   . GLU C 1 70  ? 39.439  -2.349  12.047  1.00 49.54  ? 70  GLU C C   1 
ATOM   7718  O O   . GLU C 1 70  ? 39.648  -3.137  12.964  1.00 50.24  ? 70  GLU C O   1 
ATOM   7719  C CB  . GLU C 1 70  ? 40.630  -0.118  12.056  1.00 51.77  ? 70  GLU C CB  1 
ATOM   7720  C CG  . GLU C 1 70  ? 42.033  0.498   12.061  1.00 62.47  ? 70  GLU C CG  1 
ATOM   7721  C CD  . GLU C 1 70  ? 42.172  2.024   12.133  1.00 71.34  ? 70  GLU C CD  1 
ATOM   7722  O OE1 . GLU C 1 70  ? 43.316  2.501   12.352  1.00 79.14  ? 70  GLU C OE1 1 
ATOM   7723  O OE2 . GLU C 1 70  ? 41.174  2.755   11.943  1.00 53.16  ? 70  GLU C OE2 1 
ATOM   7724  N N   . LEU C 1 71  ? 38.227  -2.205  11.459  1.00 44.92  ? 71  LEU C N   1 
ATOM   7725  C CA  . LEU C 1 71  ? 37.010  -2.771  12.049  1.00 39.99  ? 71  LEU C CA  1 
ATOM   7726  C C   . LEU C 1 71  ? 36.770  -4.217  11.623  1.00 39.97  ? 71  LEU C C   1 
ATOM   7727  O O   . LEU C 1 71  ? 36.072  -4.951  12.306  1.00 41.51  ? 71  LEU C O   1 
ATOM   7728  C CB  . LEU C 1 71  ? 35.822  -1.890  11.653  1.00 40.26  ? 71  LEU C CB  1 
ATOM   7729  C CG  . LEU C 1 71  ? 35.909  -0.457  12.178  1.00 42.34  ? 71  LEU C CG  1 
ATOM   7730  C CD1 . LEU C 1 71  ? 34.887  0.428   11.486  1.00 37.58  ? 71  LEU C CD1 1 
ATOM   7731  C CD2 . LEU C 1 71  ? 35.736  -0.435  13.693  1.00 40.41  ? 71  LEU C CD2 1 
ATOM   7732  N N   . ARG C 1 72  ? 37.338  -4.614  10.484  1.00 44.17  ? 72  ARG C N   1 
ATOM   7733  C CA  . ARG C 1 72  ? 37.097  -5.917  9.882   1.00 46.87  ? 72  ARG C CA  1 
ATOM   7734  C C   . ARG C 1 72  ? 38.226  -6.886  10.216  1.00 47.16  ? 72  ARG C C   1 
ATOM   7735  O O   . ARG C 1 72  ? 38.009  -8.091  10.304  1.00 46.28  ? 72  ARG C O   1 
ATOM   7736  C CB  . ARG C 1 72  ? 36.999  -5.777  8.353   1.00 45.17  ? 72  ARG C CB  1 
ATOM   7737  C CG  . ARG C 1 72  ? 36.773  -7.078  7.587   1.00 42.80  ? 72  ARG C CG  1 
ATOM   7738  C CD  . ARG C 1 72  ? 36.251  -6.786  6.183   1.00 41.24  ? 72  ARG C CD  1 
ATOM   7739  N NE  . ARG C 1 72  ? 36.165  -8.028  5.447   1.00 45.03  ? 72  ARG C NE  1 
ATOM   7740  C CZ  . ARG C 1 72  ? 37.188  -8.639  4.858   1.00 50.97  ? 72  ARG C CZ  1 
ATOM   7741  N NH1 . ARG C 1 72  ? 38.329  -7.998  4.673   1.00 53.84  ? 72  ARG C NH1 1 
ATOM   7742  N NH2 . ARG C 1 72  ? 37.049  -9.877  4.418   1.00 49.19  ? 72  ARG C NH2 1 
ATOM   7743  N N   . GLU C 1 73  ? 39.452  -6.372  10.308  1.00 53.15  ? 73  GLU C N   1 
ATOM   7744  C CA  . GLU C 1 73  ? 40.616  -7.243  10.385  1.00 58.62  ? 73  GLU C CA  1 
ATOM   7745  C C   . GLU C 1 73  ? 41.374  -6.929  11.653  1.00 51.71  ? 73  GLU C C   1 
ATOM   7746  O O   . GLU C 1 73  ? 41.897  -7.834  12.270  1.00 58.47  ? 73  GLU C O   1 
ATOM   7747  C CB  . GLU C 1 73  ? 41.566  -7.026  9.199   1.00 61.84  ? 73  GLU C CB  1 
ATOM   7748  C CG  . GLU C 1 73  ? 41.301  -7.904  7.985   1.00 73.04  ? 73  GLU C CG  1 
ATOM   7749  C CD  . GLU C 1 73  ? 41.851  -7.399  6.652   1.00 85.97  ? 73  GLU C CD  1 
ATOM   7750  O OE1 . GLU C 1 73  ? 41.506  -8.006  5.600   1.00 90.13  ? 73  GLU C OE1 1 
ATOM   7751  O OE2 . GLU C 1 73  ? 42.609  -6.395  6.648   1.00 79.94  ? 73  GLU C OE2 1 
ATOM   7752  N N   . GLY C 1 74  ? 41.349  -5.644  12.020  1.00 61.64  ? 74  GLY C N   1 
ATOM   7753  C CA  . GLY C 1 74  ? 42.509  -4.901  12.486  1.00 56.17  ? 74  GLY C CA  1 
ATOM   7754  C C   . GLY C 1 74  ? 42.620  -4.956  13.997  1.00 69.27  ? 74  GLY C C   1 
ATOM   7755  O O   . GLY C 1 74  ? 42.153  -5.913  14.621  1.00 86.35  ? 74  GLY C O   1 
ATOM   7756  N N   . PRO C 1 75  ? 43.262  -3.947  14.630  1.00 70.63  ? 75  PRO C N   1 
ATOM   7757  C CA  . PRO C 1 75  ? 43.390  -3.943  16.091  1.00 67.24  ? 75  PRO C CA  1 
ATOM   7758  C C   . PRO C 1 75  ? 42.050  -3.735  16.811  1.00 73.22  ? 75  PRO C C   1 
ATOM   7759  O O   . PRO C 1 75  ? 41.947  -3.970  18.018  1.00 61.90  ? 75  PRO C O   1 
ATOM   7760  C CB  . PRO C 1 75  ? 44.365  -2.782  16.367  1.00 70.15  ? 75  PRO C CB  1 
ATOM   7761  C CG  . PRO C 1 75  ? 44.276  -1.872  15.129  1.00 67.90  ? 75  PRO C CG  1 
ATOM   7762  C CD  . PRO C 1 75  ? 43.900  -2.786  13.975  1.00 68.59  ? 75  PRO C CD  1 
ATOM   7763  N N   . HIS C 1 76  ? 41.023  -3.288  16.062  1.00 72.81  ? 76  HIS C N   1 
ATOM   7764  C CA  . HIS C 1 76  ? 39.752  -2.858  16.634  1.00 62.79  ? 76  HIS C CA  1 
ATOM   7765  C C   . HIS C 1 76  ? 38.593  -3.644  16.024  1.00 54.90  ? 76  HIS C C   1 
ATOM   7766  O O   . HIS C 1 76  ? 37.543  -3.088  15.722  1.00 51.36  ? 76  HIS C O   1 
ATOM   7767  C CB  . HIS C 1 76  ? 39.578  -1.354  16.404  1.00 63.17  ? 76  HIS C CB  1 
ATOM   7768  C CG  . HIS C 1 76  ? 40.607  -0.522  17.091  1.00 72.05  ? 76  HIS C CG  1 
ATOM   7769  N ND1 . HIS C 1 76  ? 40.806  -0.542  18.463  1.00 70.56  ? 76  HIS C ND1 1 
ATOM   7770  C CD2 . HIS C 1 76  ? 41.489  0.350   16.588  1.00 67.00  ? 76  HIS C CD2 1 
ATOM   7771  C CE1 . HIS C 1 76  ? 41.770  0.310   18.772  1.00 67.68  ? 76  HIS C CE1 1 
ATOM   7772  N NE2 . HIS C 1 76  ? 42.189  0.872   17.651  1.00 72.91  ? 76  HIS C NE2 1 
ATOM   7773  N N   . LYS C 1 77  ? 38.772  -4.956  15.877  1.00 47.87  ? 77  LYS C N   1 
ATOM   7774  C CA  . LYS C 1 77  ? 37.832  -5.752  15.106  1.00 46.11  ? 77  LYS C CA  1 
ATOM   7775  C C   . LYS C 1 77  ? 36.465  -5.754  15.782  1.00 48.28  ? 77  LYS C C   1 
ATOM   7776  O O   . LYS C 1 77  ? 36.348  -6.075  16.961  1.00 48.46  ? 77  LYS C O   1 
ATOM   7777  C CB  . LYS C 1 77  ? 38.377  -7.167  14.972  1.00 49.53  ? 77  LYS C CB  1 
ATOM   7778  C CG  . LYS C 1 77  ? 37.762  -8.027  13.888  1.00 55.37  ? 77  LYS C CG  1 
ATOM   7779  C CD  . LYS C 1 77  ? 38.208  -9.482  13.992  1.00 56.45  ? 77  LYS C CD  1 
ATOM   7780  C CE  . LYS C 1 77  ? 37.308  -10.425 13.225  1.00 60.68  ? 77  LYS C CE  1 
ATOM   7781  N NZ  . LYS C 1 77  ? 37.209  -9.998  11.813  1.00 61.53  ? 77  LYS C NZ  1 
ATOM   7782  N N   . LEU C 1 78  ? 35.423  -5.384  15.031  1.00 43.96  ? 78  LEU C N   1 
ATOM   7783  C CA  . LEU C 1 78  ? 34.075  -5.450  15.562  1.00 42.48  ? 78  LEU C CA  1 
ATOM   7784  C C   . LEU C 1 78  ? 33.721  -6.897  15.844  1.00 44.74  ? 78  LEU C C   1 
ATOM   7785  O O   . LEU C 1 78  ? 34.245  -7.808  15.205  1.00 46.57  ? 78  LEU C O   1 
ATOM   7786  C CB  . LEU C 1 78  ? 33.097  -4.837  14.571  1.00 40.84  ? 78  LEU C CB  1 
ATOM   7787  C CG  . LEU C 1 78  ? 33.225  -3.334  14.428  1.00 44.89  ? 78  LEU C CG  1 
ATOM   7788  C CD1 . LEU C 1 78  ? 32.322  -2.815  13.316  1.00 44.15  ? 78  LEU C CD1 1 
ATOM   7789  C CD2 . LEU C 1 78  ? 32.921  -2.676  15.754  1.00 48.73  ? 78  LEU C CD2 1 
ATOM   7790  N N   . PRO C 1 79  ? 32.834  -7.148  16.830  1.00 43.27  ? 79  PRO C N   1 
ATOM   7791  C CA  . PRO C 1 79  ? 32.359  -8.505  17.090  1.00 42.74  ? 79  PRO C CA  1 
ATOM   7792  C C   . PRO C 1 79  ? 31.744  -9.141  15.842  1.00 47.49  ? 79  PRO C C   1 
ATOM   7793  O O   . PRO C 1 79  ? 31.125  -8.444  15.039  1.00 42.23  ? 79  PRO C O   1 
ATOM   7794  C CB  . PRO C 1 79  ? 31.318  -8.339  18.204  1.00 41.55  ? 79  PRO C CB  1 
ATOM   7795  C CG  . PRO C 1 79  ? 31.674  -7.017  18.878  1.00 41.49  ? 79  PRO C CG  1 
ATOM   7796  C CD  . PRO C 1 79  ? 32.317  -6.168  17.789  1.00 42.85  ? 79  PRO C CD  1 
ATOM   7797  N N   . THR C 1 80  ? 31.878  -10.473 15.766  1.00 47.66  ? 80  THR C N   1 
ATOM   7798  C CA  . THR C 1 80  ? 31.398  -11.313 14.688  1.00 49.16  ? 80  THR C CA  1 
ATOM   7799  C C   . THR C 1 80  ? 30.307  -12.257 15.204  1.00 55.85  ? 80  THR C C   1 
ATOM   7800  O O   . THR C 1 80  ? 29.926  -12.224 16.375  1.00 58.51  ? 80  THR C O   1 
ATOM   7801  C CB  . THR C 1 80  ? 32.550  -12.171 14.132  1.00 53.53  ? 80  THR C CB  1 
ATOM   7802  O OG1 . THR C 1 80  ? 32.881  -13.164 15.107  1.00 46.91  ? 80  THR C OG1 1 
ATOM   7803  C CG2 . THR C 1 80  ? 33.780  -11.373 13.747  1.00 49.46  ? 80  THR C CG2 1 
ATOM   7804  N N   . ALA C 1 81  ? 29.804  -13.110 14.304  1.00 57.67  ? 81  ALA C N   1 
ATOM   7805  C CA  . ALA C 1 81  ? 28.974  -14.237 14.687  1.00 56.19  ? 81  ALA C CA  1 
ATOM   7806  C C   . ALA C 1 81  ? 29.866  -15.347 15.230  1.00 57.55  ? 81  ALA C C   1 
ATOM   7807  O O   . ALA C 1 81  ? 31.048  -15.437 14.893  1.00 56.67  ? 81  ALA C O   1 
ATOM   7808  C CB  . ALA C 1 81  ? 28.165  -14.709 13.497  1.00 56.01  ? 81  ALA C CB  1 
ATOM   7809  N N   . GLU C 1 82  ? 29.285  -16.211 16.059  1.00 53.61  ? 82  GLU C N   1 
ATOM   7810  C CA  . GLU C 1 82  ? 30.012  -17.367 16.540  1.00 56.91  ? 82  GLU C CA  1 
ATOM   7811  C C   . GLU C 1 82  ? 30.532  -18.167 15.340  1.00 52.64  ? 82  GLU C C   1 
ATOM   7812  O O   . GLU C 1 82  ? 29.759  -18.655 14.519  1.00 62.77  ? 82  GLU C O   1 
ATOM   7813  C CB  . GLU C 1 82  ? 29.093  -18.209 17.434  1.00 73.46  ? 82  GLU C CB  1 
ATOM   7814  C CG  . GLU C 1 82  ? 29.793  -19.400 18.091  1.00 92.39  ? 82  GLU C CG  1 
ATOM   7815  C CD  . GLU C 1 82  ? 29.043  -20.724 17.984  1.00 103.94 ? 82  GLU C CD  1 
ATOM   7816  O OE1 . GLU C 1 82  ? 29.318  -21.495 17.014  1.00 94.29  ? 82  GLU C OE1 1 
ATOM   7817  O OE2 . GLU C 1 82  ? 28.203  -20.998 18.874  1.00 108.24 ? 82  GLU C OE2 1 
ATOM   7818  N N   . GLY C 1 83  ? 31.850  -18.348 15.260  1.00 49.20  ? 83  GLY C N   1 
ATOM   7819  C CA  . GLY C 1 83  ? 32.458  -19.161 14.223  1.00 50.92  ? 83  GLY C CA  1 
ATOM   7820  C C   . GLY C 1 83  ? 32.708  -18.364 12.948  1.00 54.51  ? 83  GLY C C   1 
ATOM   7821  O O   . GLY C 1 83  ? 33.187  -18.923 11.965  1.00 47.47  ? 83  GLY C O   1 
ATOM   7822  N N   . GLY C 1 84  ? 32.467  -17.044 13.030  1.00 53.06  ? 84  GLY C N   1 
ATOM   7823  C CA  . GLY C 1 84  ? 32.512  -16.149 11.889  1.00 54.57  ? 84  GLY C CA  1 
ATOM   7824  C C   . GLY C 1 84  ? 33.742  -15.238 11.844  1.00 48.58  ? 84  GLY C C   1 
ATOM   7825  O O   . GLY C 1 84  ? 34.445  -15.066 12.822  1.00 49.54  ? 84  GLY C O   1 
ATOM   7826  N N   . PHE C 1 85  ? 33.982  -14.665 10.660  1.00 45.96  ? 85  PHE C N   1 
ATOM   7827  C CA  . PHE C 1 85  ? 35.024  -13.685 10.452  1.00 45.33  ? 85  PHE C CA  1 
ATOM   7828  C C   . PHE C 1 85  ? 34.433  -12.289 10.238  1.00 42.94  ? 85  PHE C C   1 
ATOM   7829  O O   . PHE C 1 85  ? 34.945  -11.297 10.737  1.00 37.36  ? 85  PHE C O   1 
ATOM   7830  C CB  . PHE C 1 85  ? 35.855  -14.059 9.230   1.00 48.62  ? 85  PHE C CB  1 
ATOM   7831  C CG  . PHE C 1 85  ? 36.997  -13.112 9.011   1.00 56.62  ? 85  PHE C CG  1 
ATOM   7832  C CD1 . PHE C 1 85  ? 38.091  -13.118 9.873   1.00 62.61  ? 85  PHE C CD1 1 
ATOM   7833  C CD2 . PHE C 1 85  ? 36.958  -12.179 7.979   1.00 61.94  ? 85  PHE C CD2 1 
ATOM   7834  C CE1 . PHE C 1 85  ? 39.137  -12.219 9.692   1.00 61.59  ? 85  PHE C CE1 1 
ATOM   7835  C CE2 . PHE C 1 85  ? 38.013  -11.285 7.793   1.00 62.00  ? 85  PHE C CE2 1 
ATOM   7836  C CZ  . PHE C 1 85  ? 39.096  -11.307 8.651   1.00 60.97  ? 85  PHE C CZ  1 
ATOM   7837  N N   . GLU C 1 86  ? 33.358  -12.184 9.461   1.00 46.17  ? 86  GLU C N   1 
ATOM   7838  C CA  . GLU C 1 86  ? 32.938  -10.863 9.009   1.00 43.05  ? 86  GLU C CA  1 
ATOM   7839  C C   . GLU C 1 86  ? 32.274  -10.155 10.172  1.00 39.42  ? 86  GLU C C   1 
ATOM   7840  O O   . GLU C 1 86  ? 31.622  -10.806 10.991  1.00 44.08  ? 86  GLU C O   1 
ATOM   7841  C CB  . GLU C 1 86  ? 32.030  -10.981 7.782   1.00 43.66  ? 86  GLU C CB  1 
ATOM   7842  C CG  . GLU C 1 86  ? 32.709  -11.732 6.646   1.00 42.67  ? 86  GLU C CG  1 
ATOM   7843  C CD  . GLU C 1 86  ? 33.812  -10.980 5.927   1.00 44.05  ? 86  GLU C CD  1 
ATOM   7844  O OE1 . GLU C 1 86  ? 34.491  -11.619 5.100   1.00 54.90  ? 86  GLU C OE1 1 
ATOM   7845  O OE2 . GLU C 1 86  ? 33.981  -9.754  6.173   1.00 44.42  ? 86  GLU C OE2 1 
ATOM   7846  N N   . PRO C 1 87  ? 32.424  -8.822  10.271  1.00 36.70  ? 87  PRO C N   1 
ATOM   7847  C CA  . PRO C 1 87  ? 31.796  -8.058  11.339  1.00 39.68  ? 87  PRO C CA  1 
ATOM   7848  C C   . PRO C 1 87  ? 30.281  -7.954  11.218  1.00 46.02  ? 87  PRO C C   1 
ATOM   7849  O O   . PRO C 1 87  ? 29.772  -7.848  10.101  1.00 44.31  ? 87  PRO C O   1 
ATOM   7850  C CB  . PRO C 1 87  ? 32.414  -6.671  11.160  1.00 45.54  ? 87  PRO C CB  1 
ATOM   7851  C CG  . PRO C 1 87  ? 32.748  -6.567  9.696   1.00 39.17  ? 87  PRO C CG  1 
ATOM   7852  C CD  . PRO C 1 87  ? 33.150  -7.970  9.319   1.00 38.97  ? 87  PRO C CD  1 
ATOM   7853  N N   . LEU C 1 88  ? 29.593  -8.018  12.380  1.00 45.92  ? 88  LEU C N   1 
ATOM   7854  C CA  . LEU C 1 88  ? 28.157  -7.820  12.487  1.00 43.71  ? 88  LEU C CA  1 
ATOM   7855  C C   . LEU C 1 88  ? 27.803  -6.353  12.325  1.00 40.22  ? 88  LEU C C   1 
ATOM   7856  O O   . LEU C 1 88  ? 28.308  -5.509  13.050  1.00 45.75  ? 88  LEU C O   1 
ATOM   7857  C CB  . LEU C 1 88  ? 27.675  -8.319  13.848  1.00 45.30  ? 88  LEU C CB  1 
ATOM   7858  C CG  . LEU C 1 88  ? 27.836  -9.819  14.051  1.00 41.54  ? 88  LEU C CG  1 
ATOM   7859  C CD1 . LEU C 1 88  ? 27.029  -10.299 15.232  1.00 40.49  ? 88  LEU C CD1 1 
ATOM   7860  C CD2 . LEU C 1 88  ? 27.441  -10.554 12.791  1.00 41.67  ? 88  LEU C CD2 1 
ATOM   7861  N N   . PRO C 1 89  ? 26.874  -6.016  11.404  1.00 40.44  ? 89  PRO C N   1 
ATOM   7862  C CA  . PRO C 1 89  ? 26.330  -4.664  11.307  1.00 38.21  ? 89  PRO C CA  1 
ATOM   7863  C C   . PRO C 1 89  ? 25.726  -4.134  12.595  1.00 35.34  ? 89  PRO C C   1 
ATOM   7864  O O   . PRO C 1 89  ? 25.811  -2.927  12.836  1.00 40.43  ? 89  PRO C O   1 
ATOM   7865  C CB  . PRO C 1 89  ? 25.260  -4.718  10.215  1.00 37.91  ? 89  PRO C CB  1 
ATOM   7866  C CG  . PRO C 1 89  ? 25.103  -6.182  9.905   1.00 39.03  ? 89  PRO C CG  1 
ATOM   7867  C CD  . PRO C 1 89  ? 26.344  -6.900  10.371  1.00 37.51  ? 89  PRO C CD  1 
ATOM   7868  N N   . GLU C 1 90  ? 25.195  -5.028  13.439  1.00 37.70  ? 90  GLU C N   1 
ATOM   7869  C CA  . GLU C 1 90  ? 24.705  -4.644  14.762  1.00 38.47  ? 90  GLU C CA  1 
ATOM   7870  C C   . GLU C 1 90  ? 25.799  -3.853  15.485  1.00 42.24  ? 90  GLU C C   1 
ATOM   7871  O O   . GLU C 1 90  ? 25.540  -2.794  16.053  1.00 41.45  ? 90  GLU C O   1 
ATOM   7872  C CB  . GLU C 1 90  ? 24.282  -5.850  15.616  1.00 40.15  ? 90  GLU C CB  1 
ATOM   7873  C CG  . GLU C 1 90  ? 23.027  -6.578  15.134  1.00 48.35  ? 90  GLU C CG  1 
ATOM   7874  C CD  . GLU C 1 90  ? 23.249  -7.805  14.252  1.00 46.26  ? 90  GLU C CD  1 
ATOM   7875  O OE1 . GLU C 1 90  ? 22.537  -8.811  14.441  1.00 49.66  ? 90  GLU C OE1 1 
ATOM   7876  O OE2 . GLU C 1 90  ? 24.158  -7.760  13.400  1.00 44.61  ? 90  GLU C OE2 1 
ATOM   7877  N N   . GLY C 1 91  ? 27.047  -4.330  15.411  1.00 41.52  ? 91  GLY C N   1 
ATOM   7878  C CA  . GLY C 1 91  ? 28.113  -3.698  16.185  1.00 42.79  ? 91  GLY C CA  1 
ATOM   7879  C C   . GLY C 1 91  ? 28.532  -2.385  15.557  1.00 39.97  ? 91  GLY C C   1 
ATOM   7880  O O   . GLY C 1 91  ? 28.767  -1.383  16.241  1.00 44.97  ? 91  GLY C O   1 
ATOM   7881  N N   . LEU C 1 92  ? 28.547  -2.371  14.225  1.00 39.18  ? 92  LEU C N   1 
ATOM   7882  C CA  . LEU C 1 92  ? 28.859  -1.136  13.534  1.00 40.69  ? 92  LEU C CA  1 
ATOM   7883  C C   . LEU C 1 92  ? 27.841  -0.063  13.920  1.00 40.14  ? 92  LEU C C   1 
ATOM   7884  O O   . LEU C 1 92  ? 28.217  1.087   14.130  1.00 39.84  ? 92  LEU C O   1 
ATOM   7885  C CB  . LEU C 1 92  ? 28.898  -1.378  12.020  1.00 45.58  ? 92  LEU C CB  1 
ATOM   7886  C CG  . LEU C 1 92  ? 29.035  -0.097  11.200  1.00 45.46  ? 92  LEU C CG  1 
ATOM   7887  C CD1 . LEU C 1 92  ? 30.329  0.569   11.560  1.00 47.20  ? 92  LEU C CD1 1 
ATOM   7888  C CD2 . LEU C 1 92  ? 28.972  -0.370  9.717   1.00 47.29  ? 92  LEU C CD2 1 
ATOM   7889  N N   . TRP C 1 93  ? 26.551  -0.441  13.997  1.00 40.21  ? 93  TRP C N   1 
ATOM   7890  C CA  . TRP C 1 93  ? 25.493  0.498   14.339  1.00 34.96  ? 93  TRP C CA  1 
ATOM   7891  C C   . TRP C 1 93  ? 25.769  1.151   15.692  1.00 36.10  ? 93  TRP C C   1 
ATOM   7892  O O   . TRP C 1 93  ? 25.681  2.378   15.825  1.00 37.15  ? 93  TRP C O   1 
ATOM   7893  C CB  . TRP C 1 93  ? 24.127  -0.207  14.338  1.00 37.73  ? 93  TRP C CB  1 
ATOM   7894  C CG  . TRP C 1 93  ? 22.954  0.732   14.279  1.00 35.82  ? 93  TRP C CG  1 
ATOM   7895  C CD1 . TRP C 1 93  ? 22.724  1.713   13.353  1.00 35.37  ? 93  TRP C CD1 1 
ATOM   7896  C CD2 . TRP C 1 93  ? 21.884  0.820   15.222  1.00 32.24  ? 93  TRP C CD2 1 
ATOM   7897  N NE1 . TRP C 1 93  ? 21.567  2.373   13.638  1.00 35.99  ? 93  TRP C NE1 1 
ATOM   7898  C CE2 . TRP C 1 93  ? 21.027  1.835   14.776  1.00 33.96  ? 93  TRP C CE2 1 
ATOM   7899  C CE3 . TRP C 1 93  ? 21.558  0.115   16.380  1.00 37.91  ? 93  TRP C CE3 1 
ATOM   7900  C CZ2 . TRP C 1 93  ? 19.860  2.159   15.452  1.00 41.35  ? 93  TRP C CZ2 1 
ATOM   7901  C CZ3 . TRP C 1 93  ? 20.404  0.445   17.054  1.00 37.98  ? 93  TRP C CZ3 1 
ATOM   7902  C CH2 . TRP C 1 93  ? 19.569  1.458   16.601  1.00 36.38  ? 93  TRP C CH2 1 
ATOM   7903  N N   . TYR C 1 94  ? 26.132  0.326   16.691  1.00 42.12  ? 94  TYR C N   1 
ATOM   7904  C CA  . TYR C 1 94  ? 26.563  0.838   17.995  1.00 44.10  ? 94  TYR C CA  1 
ATOM   7905  C C   . TYR C 1 94  ? 27.656  1.891   17.833  1.00 43.43  ? 94  TYR C C   1 
ATOM   7906  O O   . TYR C 1 94  ? 27.563  2.969   18.407  1.00 39.15  ? 94  TYR C O   1 
ATOM   7907  C CB  . TYR C 1 94  ? 27.050  -0.297  18.900  1.00 44.88  ? 94  TYR C CB  1 
ATOM   7908  C CG  . TYR C 1 94  ? 27.331  0.108   20.326  1.00 48.58  ? 94  TYR C CG  1 
ATOM   7909  C CD1 . TYR C 1 94  ? 28.540  0.671   20.681  1.00 55.91  ? 94  TYR C CD1 1 
ATOM   7910  C CD2 . TYR C 1 94  ? 26.395  -0.086  21.332  1.00 50.30  ? 94  TYR C CD2 1 
ATOM   7911  C CE1 . TYR C 1 94  ? 28.819  1.030   21.990  1.00 57.25  ? 94  TYR C CE1 1 
ATOM   7912  C CE2 . TYR C 1 94  ? 26.643  0.306   22.635  1.00 49.94  ? 94  TYR C CE2 1 
ATOM   7913  C CZ  . TYR C 1 94  ? 27.863  0.864   22.976  1.00 54.95  ? 94  TYR C CZ  1 
ATOM   7914  O OH  . TYR C 1 94  ? 28.160  1.234   24.279  1.00 54.62  ? 94  TYR C OH  1 
ATOM   7915  N N   . LEU C 1 95  ? 28.672  1.576   17.011  1.00 43.09  ? 95  LEU C N   1 
ATOM   7916  C CA  . LEU C 1 95  ? 29.753  2.504   16.754  1.00 40.06  ? 95  LEU C CA  1 
ATOM   7917  C C   . LEU C 1 95  ? 29.219  3.798   16.156  1.00 43.90  ? 95  LEU C C   1 
ATOM   7918  O O   . LEU C 1 95  ? 29.594  4.872   16.625  1.00 41.27  ? 95  LEU C O   1 
ATOM   7919  C CB  . LEU C 1 95  ? 30.810  1.861   15.841  1.00 43.46  ? 95  LEU C CB  1 
ATOM   7920  C CG  . LEU C 1 95  ? 31.901  2.792   15.301  1.00 44.66  ? 95  LEU C CG  1 
ATOM   7921  C CD1 . LEU C 1 95  ? 32.584  3.583   16.411  1.00 46.77  ? 95  LEU C CD1 1 
ATOM   7922  C CD2 . LEU C 1 95  ? 32.937  1.994   14.561  1.00 48.67  ? 95  LEU C CD2 1 
ATOM   7923  N N   . LEU C 1 96  ? 28.369  3.709   15.124  1.00 39.91  ? 96  LEU C N   1 
ATOM   7924  C CA  . LEU C 1 96  ? 27.948  4.919   14.436  1.00 38.65  ? 96  LEU C CA  1 
ATOM   7925  C C   . LEU C 1 96  ? 27.229  5.845   15.419  1.00 41.43  ? 96  LEU C C   1 
ATOM   7926  O O   . LEU C 1 96  ? 27.333  7.073   15.322  1.00 42.87  ? 96  LEU C O   1 
ATOM   7927  C CB  . LEU C 1 96  ? 27.046  4.556   13.243  1.00 42.50  ? 96  LEU C CB  1 
ATOM   7928  C CG  . LEU C 1 96  ? 27.710  3.764   12.113  1.00 39.67  ? 96  LEU C CG  1 
ATOM   7929  C CD1 . LEU C 1 96  ? 26.767  3.558   10.965  1.00 40.38  ? 96  LEU C CD1 1 
ATOM   7930  C CD2 . LEU C 1 96  ? 28.949  4.447   11.588  1.00 42.70  ? 96  LEU C CD2 1 
ATOM   7931  N N   . LEU C 1 97  ? 26.477  5.258   16.355  1.00 37.08  ? 97  LEU C N   1 
ATOM   7932  C CA  . LEU C 1 97  ? 25.673  6.051   17.272  1.00 40.35  ? 97  LEU C CA  1 
ATOM   7933  C C   . LEU C 1 97  ? 26.539  6.684   18.366  1.00 40.20  ? 97  LEU C C   1 
ATOM   7934  O O   . LEU C 1 97  ? 26.457  7.892   18.607  1.00 39.58  ? 97  LEU C O   1 
ATOM   7935  C CB  . LEU C 1 97  ? 24.571  5.163   17.873  1.00 43.03  ? 97  LEU C CB  1 
ATOM   7936  C CG  . LEU C 1 97  ? 23.353  4.966   16.968  1.00 40.79  ? 97  LEU C CG  1 
ATOM   7937  C CD1 . LEU C 1 97  ? 22.468  3.856   17.466  1.00 41.74  ? 97  LEU C CD1 1 
ATOM   7938  C CD2 . LEU C 1 97  ? 22.559  6.253   16.862  1.00 47.32  ? 97  LEU C CD2 1 
ATOM   7939  N N   . THR C 1 98  ? 27.367  5.874   19.023  1.00 41.83  ? 98  THR C N   1 
ATOM   7940  C CA  . THR C 1 98  ? 28.072  6.331   20.210  1.00 44.06  ? 98  THR C CA  1 
ATOM   7941  C C   . THR C 1 98  ? 29.475  6.837   19.903  1.00 43.95  ? 98  THR C C   1 
ATOM   7942  O O   . THR C 1 98  ? 30.022  7.641   20.649  1.00 52.52  ? 98  THR C O   1 
ATOM   7943  C CB  . THR C 1 98  ? 28.139  5.237   21.267  1.00 40.03  ? 98  THR C CB  1 
ATOM   7944  O OG1 . THR C 1 98  ? 28.942  4.251   20.639  1.00 39.53  ? 98  THR C OG1 1 
ATOM   7945  C CG2 . THR C 1 98  ? 26.771  4.732   21.675  1.00 38.75  ? 98  THR C CG2 1 
ATOM   7946  N N   . GLY C 1 99  ? 30.084  6.346   18.833  1.00 50.37  ? 99  GLY C N   1 
ATOM   7947  C CA  . GLY C 1 99  ? 31.462  6.698   18.532  1.00 41.89  ? 99  GLY C CA  1 
ATOM   7948  C C   . GLY C 1 99  ? 32.447  5.811   19.278  1.00 41.49  ? 99  GLY C C   1 
ATOM   7949  O O   . GLY C 1 99  ? 33.650  6.017   19.200  1.00 49.41  ? 99  GLY C O   1 
ATOM   7950  N N   . GLU C 1 100 ? 31.922  4.761   19.909  1.00 44.88  ? 100 GLU C N   1 
ATOM   7951  C CA  . GLU C 1 100 ? 32.692  3.840   20.718  1.00 44.28  ? 100 GLU C CA  1 
ATOM   7952  C C   . GLU C 1 100 ? 32.531  2.423   20.180  1.00 42.49  ? 100 GLU C C   1 
ATOM   7953  O O   . GLU C 1 100 ? 31.502  2.031   19.627  1.00 43.39  ? 100 GLU C O   1 
ATOM   7954  C CB  . GLU C 1 100 ? 32.198  3.856   22.165  1.00 52.42  ? 100 GLU C CB  1 
ATOM   7955  C CG  . GLU C 1 100 ? 32.330  5.224   22.840  1.00 57.35  ? 100 GLU C CG  1 
ATOM   7956  C CD  . GLU C 1 100 ? 31.638  5.364   24.195  1.00 62.91  ? 100 GLU C CD  1 
ATOM   7957  O OE1 . GLU C 1 100 ? 31.687  6.481   24.715  1.00 70.20  ? 100 GLU C OE1 1 
ATOM   7958  O OE2 . GLU C 1 100 ? 31.001  4.372   24.708  1.00 58.50  ? 100 GLU C OE2 1 
ATOM   7959  N N   . LEU C 1 101 ? 33.583  1.649   20.363  1.00 45.99  ? 101 LEU C N   1 
ATOM   7960  C CA  . LEU C 1 101 ? 33.599  0.279   19.920  1.00 48.81  ? 101 LEU C CA  1 
ATOM   7961  C C   . LEU C 1 101 ? 32.757  -0.499  20.907  1.00 53.01  ? 101 LEU C C   1 
ATOM   7962  O O   . LEU C 1 101 ? 32.892  -0.331  22.105  1.00 51.69  ? 101 LEU C O   1 
ATOM   7963  C CB  . LEU C 1 101 ? 35.050  -0.197  19.864  1.00 46.28  ? 101 LEU C CB  1 
ATOM   7964  C CG  . LEU C 1 101 ? 35.891  0.557   18.831  1.00 51.74  ? 101 LEU C CG  1 
ATOM   7965  C CD1 . LEU C 1 101 ? 37.377  0.244   19.021  1.00 47.04  ? 101 LEU C CD1 1 
ATOM   7966  C CD2 . LEU C 1 101 ? 35.427  0.203   17.417  1.00 43.19  ? 101 LEU C CD2 1 
ATOM   7967  N N   . PRO C 1 102 ? 31.817  -1.314  20.417  1.00 52.70  ? 102 PRO C N   1 
ATOM   7968  C CA  . PRO C 1 102 ? 30.955  -2.077  21.301  1.00 50.66  ? 102 PRO C CA  1 
ATOM   7969  C C   . PRO C 1 102 ? 31.695  -3.266  21.885  1.00 54.21  ? 102 PRO C C   1 
ATOM   7970  O O   . PRO C 1 102 ? 32.616  -3.763  21.243  1.00 55.33  ? 102 PRO C O   1 
ATOM   7971  C CB  . PRO C 1 102 ? 29.857  -2.550  20.351  1.00 48.89  ? 102 PRO C CB  1 
ATOM   7972  C CG  . PRO C 1 102 ? 30.547  -2.655  19.022  1.00 51.27  ? 102 PRO C CG  1 
ATOM   7973  C CD  . PRO C 1 102 ? 31.528  -1.504  18.993  1.00 49.08  ? 102 PRO C CD  1 
ATOM   7974  N N   . THR C 1 103 ? 31.268  -3.726  23.074  1.00 51.94  ? 103 THR C N   1 
ATOM   7975  C CA  . THR C 1 103 ? 31.694  -5.024  23.575  1.00 55.80  ? 103 THR C CA  1 
ATOM   7976  C C   . THR C 1 103 ? 30.851  -6.100  22.910  1.00 51.95  ? 103 THR C C   1 
ATOM   7977  O O   . THR C 1 103 ? 29.833  -5.771  22.298  1.00 46.46  ? 103 THR C O   1 
ATOM   7978  C CB  . THR C 1 103 ? 31.524  -5.171  25.096  1.00 57.67  ? 103 THR C CB  1 
ATOM   7979  O OG1 . THR C 1 103 ? 30.128  -5.050  25.386  1.00 54.37  ? 103 THR C OG1 1 
ATOM   7980  C CG2 . THR C 1 103 ? 32.341  -4.170  25.883  1.00 53.37  ? 103 THR C CG2 1 
ATOM   7981  N N   . GLU C 1 104 ? 31.256  -7.366  23.094  1.00 45.98  ? 104 GLU C N   1 
ATOM   7982  C CA  . GLU C 1 104 ? 30.496  -8.513  22.625  1.00 55.37  ? 104 GLU C CA  1 
ATOM   7983  C C   . GLU C 1 104 ? 29.058  -8.432  23.114  1.00 60.48  ? 104 GLU C C   1 
ATOM   7984  O O   . GLU C 1 104 ? 28.129  -8.813  22.391  1.00 55.82  ? 104 GLU C O   1 
ATOM   7985  C CB  . GLU C 1 104 ? 31.068  -9.830  23.167  1.00 60.98  ? 104 GLU C CB  1 
ATOM   7986  C CG  . GLU C 1 104 ? 32.376  -10.245 22.517  1.00 69.72  ? 104 GLU C CG  1 
ATOM   7987  C CD  . GLU C 1 104 ? 32.307  -10.719 21.070  1.00 75.90  ? 104 GLU C CD  1 
ATOM   7988  O OE1 . GLU C 1 104 ? 33.393  -10.752 20.449  1.00 68.08  ? 104 GLU C OE1 1 
ATOM   7989  O OE2 . GLU C 1 104 ? 31.185  -11.078 20.570  1.00 61.72  ? 104 GLU C OE2 1 
ATOM   7990  N N   . GLU C 1 105 ? 28.906  -7.972  24.365  1.00 57.41  ? 105 GLU C N   1 
ATOM   7991  C CA  . GLU C 1 105 ? 27.609  -7.984  25.003  1.00 55.14  ? 105 GLU C CA  1 
ATOM   7992  C C   . GLU C 1 105 ? 26.763  -6.857  24.432  1.00 46.88  ? 105 GLU C C   1 
ATOM   7993  O O   . GLU C 1 105 ? 25.561  -7.019  24.289  1.00 48.68  ? 105 GLU C O   1 
ATOM   7994  C CB  . GLU C 1 105 ? 27.686  -7.877  26.529  1.00 64.41  ? 105 GLU C CB  1 
ATOM   7995  C CG  . GLU C 1 105 ? 26.823  -8.935  27.197  1.00 82.12  ? 105 GLU C CG  1 
ATOM   7996  C CD  . GLU C 1 105 ? 25.835  -8.418  28.225  1.00 95.82  ? 105 GLU C CD  1 
ATOM   7997  O OE1 . GLU C 1 105 ? 24.863  -7.765  27.788  1.00 92.34  ? 105 GLU C OE1 1 
ATOM   7998  O OE2 . GLU C 1 105 ? 26.022  -8.693  29.450  1.00 92.07  ? 105 GLU C OE2 1 
ATOM   7999  N N   . ASP C 1 106 ? 27.362  -5.693  24.157  1.00 50.02  ? 106 ASP C N   1 
ATOM   8000  C CA  . ASP C 1 106 ? 26.614  -4.604  23.538  1.00 48.97  ? 106 ASP C CA  1 
ATOM   8001  C C   . ASP C 1 106 ? 25.935  -5.128  22.270  1.00 48.32  ? 106 ASP C C   1 
ATOM   8002  O O   . ASP C 1 106 ? 24.769  -4.830  22.028  1.00 51.34  ? 106 ASP C O   1 
ATOM   8003  C CB  . ASP C 1 106 ? 27.489  -3.380  23.250  1.00 49.19  ? 106 ASP C CB  1 
ATOM   8004  C CG  . ASP C 1 106 ? 28.068  -2.708  24.492  1.00 62.57  ? 106 ASP C CG  1 
ATOM   8005  O OD1 . ASP C 1 106 ? 27.590  -3.040  25.594  1.00 74.17  ? 106 ASP C OD1 1 
ATOM   8006  O OD2 . ASP C 1 106 ? 29.012  -1.862  24.358  1.00 59.72  ? 106 ASP C OD2 1 
ATOM   8007  N N   . VAL C 1 107 ? 26.677  -5.918  21.484  1.00 44.89  ? 107 VAL C N   1 
ATOM   8008  C CA  . VAL C 1 107 ? 26.211  -6.396  20.201  1.00 52.42  ? 107 VAL C CA  1 
ATOM   8009  C C   . VAL C 1 107 ? 25.137  -7.460  20.382  1.00 51.98  ? 107 VAL C C   1 
ATOM   8010  O O   . VAL C 1 107 ? 24.244  -7.521  19.563  1.00 56.11  ? 107 VAL C O   1 
ATOM   8011  C CB  . VAL C 1 107 ? 27.357  -6.940  19.327  1.00 48.54  ? 107 VAL C CB  1 
ATOM   8012  C CG1 . VAL C 1 107 ? 26.849  -7.770  18.139  1.00 48.32  ? 107 VAL C CG1 1 
ATOM   8013  C CG2 . VAL C 1 107 ? 28.261  -5.815  18.872  1.00 46.72  ? 107 VAL C CG2 1 
ATOM   8014  N N   . LYS C 1 108 ? 25.289  -8.357  21.352  1.00 61.27  ? 108 LYS C N   1 
ATOM   8015  C CA  . LYS C 1 108 ? 24.303  -9.409  21.557  1.00 62.19  ? 108 LYS C CA  1 
ATOM   8016  C C   . LYS C 1 108 ? 22.970  -8.804  21.994  1.00 53.49  ? 108 LYS C C   1 
ATOM   8017  O O   . LYS C 1 108 ? 21.922  -9.358  21.666  1.00 54.34  ? 108 LYS C O   1 
ATOM   8018  C CB  . LYS C 1 108 ? 24.807  -10.444 22.568  1.00 71.40  ? 108 LYS C CB  1 
ATOM   8019  C CG  . LYS C 1 108 ? 26.045  -11.218 22.125  1.00 85.46  ? 108 LYS C CG  1 
ATOM   8020  C CD  . LYS C 1 108 ? 26.075  -12.683 22.561  1.00 103.88 ? 108 LYS C CD  1 
ATOM   8021  C CE  . LYS C 1 108 ? 26.149  -12.904 24.063  1.00 109.78 ? 108 LYS C CE  1 
ATOM   8022  N NZ  . LYS C 1 108 ? 27.542  -12.877 24.569  1.00 104.23 ? 108 LYS C NZ  1 
ATOM   8023  N N   . GLU C 1 109 ? 23.020  -7.668  22.714  1.00 52.24  ? 109 GLU C N   1 
ATOM   8024  C CA  . GLU C 1 109 ? 21.831  -6.928  23.105  1.00 53.53  ? 109 GLU C CA  1 
ATOM   8025  C C   . GLU C 1 109 ? 21.144  -6.320  21.878  1.00 51.95  ? 109 GLU C C   1 
ATOM   8026  O O   . GLU C 1 109 ? 19.925  -6.252  21.818  1.00 49.53  ? 109 GLU C O   1 
ATOM   8027  C CB  . GLU C 1 109 ? 22.140  -5.792  24.080  1.00 50.05  ? 109 GLU C CB  1 
ATOM   8028  C CG  . GLU C 1 109 ? 22.381  -6.249  25.507  1.00 63.32  ? 109 GLU C CG  1 
ATOM   8029  C CD  . GLU C 1 109 ? 22.808  -5.178  26.519  1.00 67.57  ? 109 GLU C CD  1 
ATOM   8030  O OE1 . GLU C 1 109 ? 23.190  -5.580  27.632  1.00 77.47  ? 109 GLU C OE1 1 
ATOM   8031  O OE2 . GLU C 1 109 ? 22.771  -3.948  26.221  1.00 61.45  ? 109 GLU C OE2 1 
ATOM   8032  N N   . ILE C 1 110 ? 21.915  -5.801  20.928  1.00 50.91  ? 110 ILE C N   1 
ATOM   8033  C CA  . ILE C 1 110 ? 21.307  -5.194  19.756  1.00 53.51  ? 110 ILE C CA  1 
ATOM   8034  C C   . ILE C 1 110 ? 20.728  -6.299  18.876  1.00 48.96  ? 110 ILE C C   1 
ATOM   8035  O O   . ILE C 1 110 ? 19.580  -6.171  18.467  1.00 45.01  ? 110 ILE C O   1 
ATOM   8036  C CB  . ILE C 1 110 ? 22.286  -4.279  19.004  1.00 52.16  ? 110 ILE C CB  1 
ATOM   8037  C CG1 . ILE C 1 110 ? 22.603  -3.017  19.805  1.00 50.84  ? 110 ILE C CG1 1 
ATOM   8038  C CG2 . ILE C 1 110 ? 21.735  -3.925  17.632  1.00 62.77  ? 110 ILE C CG2 1 
ATOM   8039  C CD1 . ILE C 1 110 ? 23.867  -2.325  19.353  1.00 52.66  ? 110 ILE C CD1 1 
ATOM   8040  N N   . SER C 1 111 ? 21.464  -7.408  18.690  1.00 45.94  ? 111 SER C N   1 
ATOM   8041  C CA  . SER C 1 111 ? 20.959  -8.556  17.939  1.00 53.80  ? 111 SER C CA  1 
ATOM   8042  C C   . SER C 1 111 ? 19.613  -9.053  18.461  1.00 47.63  ? 111 SER C C   1 
ATOM   8043  O O   . SER C 1 111 ? 18.775  -9.462  17.657  1.00 48.58  ? 111 SER C O   1 
ATOM   8044  C CB  . SER C 1 111 ? 21.932  -9.687  17.897  1.00 47.28  ? 111 SER C CB  1 
ATOM   8045  O OG  . SER C 1 111 ? 23.054  -9.307  17.122  1.00 55.22  ? 111 SER C OG  1 
ATOM   8046  N N   . ALA C 1 112 ? 19.445  -9.038  19.790  1.00 48.94  ? 112 ALA C N   1 
ATOM   8047  C CA  . ALA C 1 112 ? 18.277  -9.590  20.460  1.00 53.07  ? 112 ALA C CA  1 
ATOM   8048  C C   . ALA C 1 112 ? 17.103  -8.627  20.332  1.00 48.99  ? 112 ALA C C   1 
ATOM   8049  O O   . ALA C 1 112 ? 15.976  -9.043  20.140  1.00 52.98  ? 112 ALA C O   1 
ATOM   8050  C CB  . ALA C 1 112 ? 18.584  -9.850  21.925  1.00 50.52  ? 112 ALA C CB  1 
ATOM   8051  N N   . GLU C 1 113 ? 17.391  -7.334  20.453  1.00 48.86  ? 113 GLU C N   1 
ATOM   8052  C CA  . GLU C 1 113 ? 16.391  -6.307  20.257  1.00 52.67  ? 113 GLU C CA  1 
ATOM   8053  C C   . GLU C 1 113 ? 15.863  -6.393  18.817  1.00 56.27  ? 113 GLU C C   1 
ATOM   8054  O O   . GLU C 1 113 ? 14.669  -6.352  18.581  1.00 58.57  ? 113 GLU C O   1 
ATOM   8055  C CB  . GLU C 1 113 ? 17.038  -4.981  20.642  1.00 57.17  ? 113 GLU C CB  1 
ATOM   8056  C CG  . GLU C 1 113 ? 16.098  -3.951  21.231  1.00 69.91  ? 113 GLU C CG  1 
ATOM   8057  C CD  . GLU C 1 113 ? 15.362  -4.328  22.504  1.00 62.27  ? 113 GLU C CD  1 
ATOM   8058  O OE1 . GLU C 1 113 ? 14.153  -4.484  22.420  1.00 71.00  ? 113 GLU C OE1 1 
ATOM   8059  O OE2 . GLU C 1 113 ? 15.994  -4.441  23.564  1.00 67.79  ? 113 GLU C OE2 1 
ATOM   8060  N N   . PHE C 1 114 ? 16.742  -6.553  17.833  1.00 49.98  ? 114 PHE C N   1 
ATOM   8061  C CA  . PHE C 1 114 ? 16.299  -6.763  16.471  1.00 58.14  ? 114 PHE C CA  1 
ATOM   8062  C C   . PHE C 1 114 ? 15.504  -8.064  16.367  1.00 60.28  ? 114 PHE C C   1 
ATOM   8063  O O   . PHE C 1 114 ? 14.511  -8.121  15.657  1.00 64.35  ? 114 PHE C O   1 
ATOM   8064  C CB  . PHE C 1 114 ? 17.482  -6.793  15.502  1.00 54.60  ? 114 PHE C CB  1 
ATOM   8065  C CG  . PHE C 1 114 ? 18.181  -5.474  15.292  1.00 54.01  ? 114 PHE C CG  1 
ATOM   8066  C CD1 . PHE C 1 114 ? 17.688  -4.295  15.821  1.00 54.44  ? 114 PHE C CD1 1 
ATOM   8067  C CD2 . PHE C 1 114 ? 19.348  -5.411  14.556  1.00 48.82  ? 114 PHE C CD2 1 
ATOM   8068  C CE1 . PHE C 1 114 ? 18.334  -3.088  15.602  1.00 47.06  ? 114 PHE C CE1 1 
ATOM   8069  C CE2 . PHE C 1 114 ? 19.981  -4.197  14.338  1.00 47.83  ? 114 PHE C CE2 1 
ATOM   8070  C CZ  . PHE C 1 114 ? 19.481  -3.039  14.874  1.00 42.01  ? 114 PHE C CZ  1 
ATOM   8071  N N   . THR C 1 115 ? 15.926  -9.109  17.070  1.00 53.28  ? 115 THR C N   1 
ATOM   8072  C CA  . THR C 1 115 ? 15.316  -10.416 16.882  1.00 59.58  ? 115 THR C CA  1 
ATOM   8073  C C   . THR C 1 115 ? 13.873  -10.417 17.403  1.00 57.16  ? 115 THR C C   1 
ATOM   8074  O O   . THR C 1 115 ? 12.970  -10.962 16.766  1.00 59.52  ? 115 THR C O   1 
ATOM   8075  C CB  . THR C 1 115 ? 16.248  -11.509 17.431  1.00 63.60  ? 115 THR C CB  1 
ATOM   8076  O OG1 . THR C 1 115 ? 17.004  -11.967 16.302  1.00 60.24  ? 115 THR C OG1 1 
ATOM   8077  C CG2 . THR C 1 115 ? 15.523  -12.668 18.089  1.00 66.47  ? 115 THR C CG2 1 
ATOM   8078  N N   . LYS C 1 116 ? 13.644  -9.788  18.552  1.00 50.75  ? 116 LYS C N   1 
ATOM   8079  C CA  . LYS C 1 116 ? 12.306  -9.692  19.102  1.00 54.45  ? 116 LYS C CA  1 
ATOM   8080  C C   . LYS C 1 116 ? 11.411  -8.834  18.190  1.00 49.81  ? 116 LYS C C   1 
ATOM   8081  O O   . LYS C 1 116 ? 10.308  -9.218  17.864  1.00 41.95  ? 116 LYS C O   1 
ATOM   8082  C CB  . LYS C 1 116 ? 12.411  -9.171  20.537  1.00 57.96  ? 116 LYS C CB  1 
ATOM   8083  C CG  . LYS C 1 116 ? 11.160  -8.524  21.121  1.00 78.97  ? 116 LYS C CG  1 
ATOM   8084  C CD  . LYS C 1 116 ? 11.211  -8.400  22.654  1.00 100.65 ? 116 LYS C CD  1 
ATOM   8085  C CE  . LYS C 1 116 ? 10.753  -7.059  23.208  1.00 108.39 ? 116 LYS C CE  1 
ATOM   8086  N NZ  . LYS C 1 116 ? 11.840  -6.041  23.222  1.00 94.89  ? 116 LYS C NZ  1 
ATOM   8087  N N   . ARG C 1 117 ? 11.898  -7.682  17.732  1.00 46.58  ? 117 ARG C N   1 
ATOM   8088  C CA  . ARG C 1 117 ? 11.083  -6.719  17.021  1.00 42.65  ? 117 ARG C CA  1 
ATOM   8089  C C   . ARG C 1 117 ? 10.790  -7.189  15.594  1.00 41.44  ? 117 ARG C C   1 
ATOM   8090  O O   . ARG C 1 117 ? 9.856   -6.703  14.949  1.00 39.17  ? 117 ARG C O   1 
ATOM   8091  C CB  . ARG C 1 117 ? 11.773  -5.361  17.139  1.00 41.86  ? 117 ARG C CB  1 
ATOM   8092  C CG  . ARG C 1 117 ? 11.733  -4.831  18.565  1.00 42.85  ? 117 ARG C CG  1 
ATOM   8093  C CD  . ARG C 1 117 ? 12.575  -3.599  18.717  1.00 49.51  ? 117 ARG C CD  1 
ATOM   8094  N NE  . ARG C 1 117 ? 12.803  -3.316  20.128  1.00 55.86  ? 117 ARG C NE  1 
ATOM   8095  C CZ  . ARG C 1 117 ? 12.401  -2.219  20.754  1.00 49.68  ? 117 ARG C CZ  1 
ATOM   8096  N NH1 . ARG C 1 117 ? 11.524  -1.430  20.182  1.00 42.30  ? 117 ARG C NH1 1 
ATOM   8097  N NH2 . ARG C 1 117 ? 12.843  -1.940  21.964  1.00 53.97  ? 117 ARG C NH2 1 
ATOM   8098  N N   . MET C 1 118 ? 11.526  -8.208  15.156  1.00 44.66  ? 118 MET C N   1 
ATOM   8099  C CA  . MET C 1 118 ? 11.371  -8.809  13.843  1.00 52.35  ? 118 MET C CA  1 
ATOM   8100  C C   . MET C 1 118 ? 10.051  -9.575  13.799  1.00 47.87  ? 118 MET C C   1 
ATOM   8101  O O   . MET C 1 118 ? 9.499   -9.834  12.721  1.00 41.58  ? 118 MET C O   1 
ATOM   8102  C CB  . MET C 1 118 ? 12.556  -9.733  13.553  1.00 49.66  ? 118 MET C CB  1 
ATOM   8103  C CG  . MET C 1 118 ? 12.763  -10.029 12.112  1.00 55.49  ? 118 MET C CG  1 
ATOM   8104  S SD  . MET C 1 118 ? 14.429  -10.709 11.748  1.00 52.50  ? 118 MET C SD  1 
ATOM   8105  C CE  . MET C 1 118 ? 15.451  -9.295  12.140  1.00 50.64  ? 118 MET C CE  1 
ATOM   8106  N N   . GLN C 1 119 ? 9.552   -9.919  14.990  1.00 45.37  ? 119 GLN C N   1 
ATOM   8107  C CA  . GLN C 1 119 ? 8.300   -10.638 15.119  1.00 43.88  ? 119 GLN C CA  1 
ATOM   8108  C C   . GLN C 1 119 ? 7.114   -9.675  15.110  1.00 41.22  ? 119 GLN C C   1 
ATOM   8109  O O   . GLN C 1 119 ? 5.980   -10.136 15.092  1.00 38.68  ? 119 GLN C O   1 
ATOM   8110  C CB  . GLN C 1 119 ? 8.261   -11.419 16.436  1.00 50.65  ? 119 GLN C CB  1 
ATOM   8111  C CG  . GLN C 1 119 ? 9.249   -12.582 16.543  1.00 56.35  ? 119 GLN C CG  1 
ATOM   8112  C CD  . GLN C 1 119 ? 8.989   -13.707 15.569  1.00 58.14  ? 119 GLN C CD  1 
ATOM   8113  O OE1 . GLN C 1 119 ? 7.859   -13.982 15.188  1.00 57.31  ? 119 GLN C OE1 1 
ATOM   8114  N NE2 . GLN C 1 119 ? 10.042  -14.369 15.123  1.00 58.44  ? 119 GLN C NE2 1 
ATOM   8115  N N   . ASN C 1 120 ? 7.358   -8.356  15.150  1.00 39.40  ? 120 ASN C N   1 
ATOM   8116  C CA  . ASN C 1 120 ? 6.303   -7.380  15.349  1.00 40.15  ? 120 ASN C CA  1 
ATOM   8117  C C   . ASN C 1 120 ? 6.008   -6.551  14.099  1.00 38.69  ? 120 ASN C C   1 
ATOM   8118  O O   . ASN C 1 120 ? 5.584   -5.407  14.201  1.00 43.31  ? 120 ASN C O   1 
ATOM   8119  C CB  . ASN C 1 120 ? 6.638   -6.378  16.457  1.00 48.58  ? 120 ASN C CB  1 
ATOM   8120  C CG  . ASN C 1 120 ? 6.895   -6.966  17.835  1.00 50.39  ? 120 ASN C CG  1 
ATOM   8121  O OD1 . ASN C 1 120 ? 7.408   -6.267  18.709  1.00 61.04  ? 120 ASN C OD1 1 
ATOM   8122  N ND2 . ASN C 1 120 ? 6.574   -8.225  18.050  1.00 43.99  ? 120 ASN C ND2 1 
ATOM   8123  N N   . VAL C 1 121 ? 6.179   -7.103  12.907  1.00 34.46  ? 121 VAL C N   1 
ATOM   8124  C CA  . VAL C 1 121 ? 5.728   -6.407  11.721  1.00 34.51  ? 121 VAL C CA  1 
ATOM   8125  C C   . VAL C 1 121 ? 4.215   -6.539  11.619  1.00 33.97  ? 121 VAL C C   1 
ATOM   8126  O O   . VAL C 1 121 ? 3.710   -7.629  11.437  1.00 40.61  ? 121 VAL C O   1 
ATOM   8127  C CB  . VAL C 1 121 ? 6.409   -6.912  10.438  1.00 31.73  ? 121 VAL C CB  1 
ATOM   8128  C CG1 . VAL C 1 121 ? 5.980   -6.110  9.221   1.00 36.91  ? 121 VAL C CG1 1 
ATOM   8129  C CG2 . VAL C 1 121 ? 7.906   -6.801  10.561  1.00 36.79  ? 121 VAL C CG2 1 
ATOM   8130  N N   . PRO C 1 122 ? 3.450   -5.428  11.587  1.00 35.74  ? 122 PRO C N   1 
ATOM   8131  C CA  . PRO C 1 122 ? 1.993   -5.492  11.484  1.00 39.71  ? 122 PRO C CA  1 
ATOM   8132  C C   . PRO C 1 122 ? 1.483   -6.297  10.294  1.00 37.09  ? 122 PRO C C   1 
ATOM   8133  O O   . PRO C 1 122 ? 2.037   -6.192  9.213   1.00 39.31  ? 122 PRO C O   1 
ATOM   8134  C CB  . PRO C 1 122 ? 1.578   -4.014  11.276  1.00 35.17  ? 122 PRO C CB  1 
ATOM   8135  C CG  . PRO C 1 122 ? 2.724   -3.225  11.843  1.00 34.76  ? 122 PRO C CG  1 
ATOM   8136  C CD  . PRO C 1 122 ? 3.942   -4.052  11.511  1.00 33.33  ? 122 PRO C CD  1 
ATOM   8137  N N   . GLN C 1 123 ? 0.358   -6.993  10.467  1.00 36.78  ? 123 GLN C N   1 
ATOM   8138  C CA  . GLN C 1 123 ? -0.205  -7.756  9.376   1.00 35.94  ? 123 GLN C CA  1 
ATOM   8139  C C   . GLN C 1 123 ? -0.610  -6.834  8.228   1.00 34.43  ? 123 GLN C C   1 
ATOM   8140  O O   . GLN C 1 123 ? -0.532  -7.237  7.064   1.00 34.38  ? 123 GLN C O   1 
ATOM   8141  C CB  . GLN C 1 123 ? -1.329  -8.636  9.895   1.00 40.40  ? 123 GLN C CB  1 
ATOM   8142  C CG  . GLN C 1 123 ? -2.058  -9.383  8.789   1.00 46.43  ? 123 GLN C CG  1 
ATOM   8143  C CD  . GLN C 1 123 ? -1.192  -10.386 8.062   1.00 51.72  ? 123 GLN C CD  1 
ATOM   8144  O OE1 . GLN C 1 123 ? -0.541  -11.246 8.663   1.00 53.46  ? 123 GLN C OE1 1 
ATOM   8145  N NE2 . GLN C 1 123 ? -1.193  -10.290 6.740   1.00 46.15  ? 123 GLN C NE2 1 
ATOM   8146  N N   . TYR C 1 124 ? -0.992  -5.576  8.517   1.00 36.41  ? 124 TYR C N   1 
ATOM   8147  C CA  . TYR C 1 124 ? -1.474  -4.707  7.442   1.00 34.38  ? 124 TYR C CA  1 
ATOM   8148  C C   . TYR C 1 124 ? -0.322  -4.327  6.498   1.00 31.45  ? 124 TYR C C   1 
ATOM   8149  O O   . TYR C 1 124 ? -0.568  -3.916  5.383   1.00 29.55  ? 124 TYR C O   1 
ATOM   8150  C CB  . TYR C 1 124 ? -2.216  -3.486  7.981   1.00 36.45  ? 124 TYR C CB  1 
ATOM   8151  C CG  . TYR C 1 124 ? -1.365  -2.542  8.796   1.00 35.90  ? 124 TYR C CG  1 
ATOM   8152  C CD1 . TYR C 1 124 ? -0.526  -1.633  8.185   1.00 35.77  ? 124 TYR C CD1 1 
ATOM   8153  C CD2 . TYR C 1 124 ? -1.423  -2.546  10.190  1.00 35.37  ? 124 TYR C CD2 1 
ATOM   8154  C CE1 . TYR C 1 124 ? 0.289   -0.786  8.926   1.00 36.21  ? 124 TYR C CE1 1 
ATOM   8155  C CE2 . TYR C 1 124 ? -0.653  -1.678  10.941  1.00 34.23  ? 124 TYR C CE2 1 
ATOM   8156  C CZ  . TYR C 1 124 ? 0.220   -0.815  10.306  1.00 36.96  ? 124 TYR C CZ  1 
ATOM   8157  O OH  . TYR C 1 124 ? 1.022   0.001   11.034  1.00 39.45  ? 124 TYR C OH  1 
ATOM   8158  N N   . VAL C 1 125 ? 0.946   -4.480  6.916   1.00 30.88  ? 125 VAL C N   1 
ATOM   8159  C CA  . VAL C 1 125 ? 2.069   -4.146  6.038   1.00 31.98  ? 125 VAL C CA  1 
ATOM   8160  C C   . VAL C 1 125 ? 2.137   -5.175  4.910   1.00 34.36  ? 125 VAL C C   1 
ATOM   8161  O O   . VAL C 1 125 ? 2.313   -4.802  3.757   1.00 35.56  ? 125 VAL C O   1 
ATOM   8162  C CB  . VAL C 1 125 ? 3.399   -4.013  6.806   1.00 31.45  ? 125 VAL C CB  1 
ATOM   8163  C CG1 . VAL C 1 125 ? 4.621   -4.149  5.910   1.00 34.87  ? 125 VAL C CG1 1 
ATOM   8164  C CG2 . VAL C 1 125 ? 3.454   -2.696  7.560   1.00 35.95  ? 125 VAL C CG2 1 
ATOM   8165  N N   . PHE C 1 126 ? 1.917   -6.454  5.241   1.00 32.28  ? 126 PHE C N   1 
ATOM   8166  C CA  . PHE C 1 126 ? 1.792   -7.509  4.245   1.00 34.63  ? 126 PHE C CA  1 
ATOM   8167  C C   . PHE C 1 126 ? 0.574   -7.295  3.351   1.00 34.94  ? 126 PHE C C   1 
ATOM   8168  O O   . PHE C 1 126 ? 0.666   -7.507  2.142   1.00 38.19  ? 126 PHE C O   1 
ATOM   8169  C CB  . PHE C 1 126 ? 1.812   -8.884  4.927   1.00 30.73  ? 126 PHE C CB  1 
ATOM   8170  C CG  . PHE C 1 126 ? 3.031   -9.070  5.798   1.00 34.86  ? 126 PHE C CG  1 
ATOM   8171  C CD1 . PHE C 1 126 ? 4.293   -9.194  5.236   1.00 33.26  ? 126 PHE C CD1 1 
ATOM   8172  C CD2 . PHE C 1 126 ? 2.930   -9.091  7.179   1.00 42.50  ? 126 PHE C CD2 1 
ATOM   8173  C CE1 . PHE C 1 126 ? 5.417   -9.357  6.023   1.00 37.88  ? 126 PHE C CE1 1 
ATOM   8174  C CE2 . PHE C 1 126 ? 4.059   -9.272  7.972   1.00 46.31  ? 126 PHE C CE2 1 
ATOM   8175  C CZ  . PHE C 1 126 ? 5.301   -9.388  7.394   1.00 46.95  ? 126 PHE C CZ  1 
ATOM   8176  N N   . ASP C 1 127 ? -0.566  -6.867  3.911   1.00 34.70  ? 127 ASP C N   1 
ATOM   8177  C CA  . ASP C 1 127 ? -1.725  -6.644  3.070   1.00 34.37  ? 127 ASP C CA  1 
ATOM   8178  C C   . ASP C 1 127 ? -1.370  -5.545  2.078   1.00 39.55  ? 127 ASP C C   1 
ATOM   8179  O O   . ASP C 1 127 ? -1.747  -5.629  0.920   1.00 40.03  ? 127 ASP C O   1 
ATOM   8180  C CB  . ASP C 1 127 ? -2.984  -6.205  3.835   1.00 39.84  ? 127 ASP C CB  1 
ATOM   8181  C CG  . ASP C 1 127 ? -3.404  -7.058  5.021   1.00 39.61  ? 127 ASP C CG  1 
ATOM   8182  O OD1 . ASP C 1 127 ? -2.907  -8.180  5.130   1.00 40.19  ? 127 ASP C OD1 1 
ATOM   8183  O OD2 . ASP C 1 127 ? -4.241  -6.566  5.865   1.00 39.26  ? 127 ASP C OD2 1 
ATOM   8184  N N   . VAL C 1 128 ? -0.718  -4.476  2.559   1.00 34.46  ? 128 VAL C N   1 
ATOM   8185  C CA  . VAL C 1 128 ? -0.318  -3.416  1.658   1.00 37.09  ? 128 VAL C CA  1 
ATOM   8186  C C   . VAL C 1 128 ? 0.618   -3.974  0.586   1.00 37.00  ? 128 VAL C C   1 
ATOM   8187  O O   . VAL C 1 128 ? 0.459   -3.630  -0.590  1.00 35.86  ? 128 VAL C O   1 
ATOM   8188  C CB  . VAL C 1 128 ? 0.350   -2.248  2.388   1.00 37.91  ? 128 VAL C CB  1 
ATOM   8189  C CG1 . VAL C 1 128 ? 1.155   -1.394  1.432   1.00 34.90  ? 128 VAL C CG1 1 
ATOM   8190  C CG2 . VAL C 1 128 ? -0.660  -1.416  3.145   1.00 33.56  ? 128 VAL C CG2 1 
ATOM   8191  N N   . LEU C 1 129 ? 1.562   -4.842  0.970   1.00 37.17  ? 129 LEU C N   1 
ATOM   8192  C CA  . LEU C 1 129 ? 2.507   -5.378  -0.010  1.00 37.73  ? 129 LEU C CA  1 
ATOM   8193  C C   . LEU C 1 129 ? 1.790   -6.248  -1.035  1.00 36.91  ? 129 LEU C C   1 
ATOM   8194  O O   . LEU C 1 129 ? 2.119   -6.131  -2.222  1.00 42.13  ? 129 LEU C O   1 
ATOM   8195  C CB  . LEU C 1 129 ? 3.615   -6.181  0.654   1.00 35.17  ? 129 LEU C CB  1 
ATOM   8196  C CG  . LEU C 1 129 ? 4.664   -5.341  1.364   1.00 37.93  ? 129 LEU C CG  1 
ATOM   8197  C CD1 . LEU C 1 129 ? 5.573   -6.201  2.197   1.00 39.23  ? 129 LEU C CD1 1 
ATOM   8198  C CD2 . LEU C 1 129 ? 5.478   -4.560  0.362   1.00 42.69  ? 129 LEU C CD2 1 
ATOM   8199  N N   . ARG C 1 130 ? 0.820   -7.064  -0.573  1.00 35.40  ? 130 ARG C N   1 
ATOM   8200  C CA  . ARG C 1 130 ? 0.068   -7.990  -1.424  1.00 38.21  ? 130 ARG C CA  1 
ATOM   8201  C C   . ARG C 1 130 ? -0.859  -7.236  -2.372  1.00 35.26  ? 130 ARG C C   1 
ATOM   8202  O O   . ARG C 1 130 ? -1.148  -7.725  -3.451  1.00 38.13  ? 130 ARG C O   1 
ATOM   8203  C CB  . ARG C 1 130 ? -0.783  -9.035  -0.679  1.00 33.30  ? 130 ARG C CB  1 
ATOM   8204  C CG  . ARG C 1 130 ? 0.027   -10.145 -0.035  1.00 41.03  ? 130 ARG C CG  1 
ATOM   8205  C CD  . ARG C 1 130 ? -0.705  -11.432 0.276   1.00 41.25  ? 130 ARG C CD  1 
ATOM   8206  N NE  . ARG C 1 130 ? -0.894  -12.283 -0.897  1.00 40.71  ? 130 ARG C NE  1 
ATOM   8207  C CZ  . ARG C 1 130 ? 0.039   -13.064 -1.442  1.00 43.95  ? 130 ARG C CZ  1 
ATOM   8208  N NH1 . ARG C 1 130 ? -0.310  -13.947 -2.370  1.00 42.43  ? 130 ARG C NH1 1 
ATOM   8209  N NH2 . ARG C 1 130 ? 1.299   -13.000 -1.024  1.00 39.51  ? 130 ARG C NH2 1 
ATOM   8210  N N   . ALA C 1 131 ? -1.338  -6.065  -1.972  1.00 36.50  ? 131 ALA C N   1 
ATOM   8211  C CA  . ALA C 1 131 ? -2.255  -5.319  -2.826  1.00 35.78  ? 131 ALA C CA  1 
ATOM   8212  C C   . ALA C 1 131 ? -1.517  -4.657  -3.994  1.00 36.41  ? 131 ALA C C   1 
ATOM   8213  O O   . ALA C 1 131 ? -2.122  -4.243  -4.983  1.00 33.63  ? 131 ALA C O   1 
ATOM   8214  C CB  . ALA C 1 131 ? -2.930  -4.293  -1.987  1.00 39.22  ? 131 ALA C CB  1 
ATOM   8215  N N   . MET C 1 132 ? -0.193  -4.569  -3.888  1.00 36.02  ? 132 MET C N   1 
ATOM   8216  C CA  . MET C 1 132 ? 0.609   -4.047  -4.982  1.00 39.54  ? 132 MET C CA  1 
ATOM   8217  C C   . MET C 1 132 ? 0.749   -5.139  -6.042  1.00 33.49  ? 132 MET C C   1 
ATOM   8218  O O   . MET C 1 132 ? 0.981   -6.275  -5.714  1.00 42.64  ? 132 MET C O   1 
ATOM   8219  C CB  . MET C 1 132 ? 1.974   -3.600  -4.458  1.00 39.01  ? 132 MET C CB  1 
ATOM   8220  C CG  . MET C 1 132 ? 1.873   -2.328  -3.632  1.00 45.05  ? 132 MET C CG  1 
ATOM   8221  S SD  . MET C 1 132 ? 3.450   -1.824  -2.909  1.00 46.14  ? 132 MET C SD  1 
ATOM   8222  C CE  . MET C 1 132 ? 3.973   -0.639  -4.131  1.00 43.35  ? 132 MET C CE  1 
ATOM   8223  N N   . PRO C 1 133 ? 0.586   -4.868  -7.352  1.00 34.50  ? 133 PRO C N   1 
ATOM   8224  C CA  . PRO C 1 133 ? 0.800   -5.889  -8.370  1.00 32.50  ? 133 PRO C CA  1 
ATOM   8225  C C   . PRO C 1 133 ? 2.245   -6.382  -8.321  1.00 31.05  ? 133 PRO C C   1 
ATOM   8226  O O   . PRO C 1 133 ? 3.169   -5.600  -8.182  1.00 30.75  ? 133 PRO C O   1 
ATOM   8227  C CB  . PRO C 1 133 ? 0.511   -5.177  -9.679  1.00 35.48  ? 133 PRO C CB  1 
ATOM   8228  C CG  . PRO C 1 133 ? -0.280  -3.973  -9.280  1.00 36.26  ? 133 PRO C CG  1 
ATOM   8229  C CD  . PRO C 1 133 ? 0.274   -3.576  -7.940  1.00 33.79  ? 133 PRO C CD  1 
ATOM   8230  N N   . VAL C 1 134 ? 2.400   -7.694  -8.464  1.00 32.25  ? 134 VAL C N   1 
ATOM   8231  C CA  . VAL C 1 134 ? 3.611   -8.415  -8.188  1.00 30.61  ? 134 VAL C CA  1 
ATOM   8232  C C   . VAL C 1 134 ? 4.740   -7.983  -9.123  1.00 30.21  ? 134 VAL C C   1 
ATOM   8233  O O   . VAL C 1 134 ? 5.908   -8.166  -8.790  1.00 30.46  ? 134 VAL C O   1 
ATOM   8234  C CB  . VAL C 1 134 ? 3.361   -9.933  -8.292  1.00 36.42  ? 134 VAL C CB  1 
ATOM   8235  C CG1 . VAL C 1 134 ? 3.189   -10.416 -9.740  1.00 33.50  ? 134 VAL C CG1 1 
ATOM   8236  C CG2 . VAL C 1 134 ? 4.503   -10.699 -7.644  1.00 37.60  ? 134 VAL C CG2 1 
ATOM   8237  N N   . ASP C 1 135 ? 4.400   -7.438  -10.289 1.00 30.10  ? 135 ASP C N   1 
ATOM   8238  C CA  . ASP C 1 135 ? 5.397   -6.943  -11.233 1.00 38.81  ? 135 ASP C CA  1 
ATOM   8239  C C   . ASP C 1 135 ? 5.798   -5.497  -10.923 1.00 40.03  ? 135 ASP C C   1 
ATOM   8240  O O   . ASP C 1 135 ? 6.520   -4.896  -11.694 1.00 36.27  ? 135 ASP C O   1 
ATOM   8241  C CB  . ASP C 1 135 ? 4.893   -6.984  -12.683 1.00 35.07  ? 135 ASP C CB  1 
ATOM   8242  C CG  . ASP C 1 135 ? 3.693   -6.081  -12.935 1.00 44.16  ? 135 ASP C CG  1 
ATOM   8243  O OD1 . ASP C 1 135 ? 3.118   -5.563  -11.923 1.00 43.32  ? 135 ASP C OD1 1 
ATOM   8244  O OD2 . ASP C 1 135 ? 3.333   -5.875  -14.142 1.00 43.37  ? 135 ASP C OD2 1 
ATOM   8245  N N   . THR C 1 136 ? 5.343   -4.908  -9.815  1.00 40.72  ? 136 THR C N   1 
ATOM   8246  C CA  . THR C 1 136 ? 5.835   -3.590  -9.428  1.00 35.91  ? 136 THR C CA  1 
ATOM   8247  C C   . THR C 1 136 ? 7.319   -3.707  -9.034  1.00 39.00  ? 136 THR C C   1 
ATOM   8248  O O   . THR C 1 136 ? 7.731   -4.718  -8.454  1.00 36.25  ? 136 THR C O   1 
ATOM   8249  C CB  . THR C 1 136 ? 4.996   -3.044  -8.266  1.00 38.75  ? 136 THR C CB  1 
ATOM   8250  O OG1 . THR C 1 136 ? 3.583   -3.061  -8.544  1.00 31.86  ? 136 THR C OG1 1 
ATOM   8251  C CG2 . THR C 1 136 ? 5.437   -1.646  -7.896  1.00 40.89  ? 136 THR C CG2 1 
ATOM   8252  N N   . HIS C 1 137 ? 8.108   -2.663  -9.328  1.00 30.64  ? 137 HIS C N   1 
ATOM   8253  C CA  . HIS C 1 137 ? 9.517   -2.632  -9.026  1.00 34.27  ? 137 HIS C CA  1 
ATOM   8254  C C   . HIS C 1 137 ? 9.752   -2.890  -7.531  1.00 37.66  ? 137 HIS C C   1 
ATOM   8255  O O   . HIS C 1 137 ? 9.081   -2.336  -6.671  1.00 35.81  ? 137 HIS C O   1 
ATOM   8256  C CB  . HIS C 1 137 ? 10.091  -1.283  -9.482  1.00 37.25  ? 137 HIS C CB  1 
ATOM   8257  C CG  . HIS C 1 137 ? 11.569  -1.294  -9.458  1.00 34.25  ? 137 HIS C CG  1 
ATOM   8258  N ND1 . HIS C 1 137 ? 12.265  -1.360  -8.262  1.00 34.28  ? 137 HIS C ND1 1 
ATOM   8259  C CD2 . HIS C 1 137 ? 12.483  -1.406  -10.476 1.00 31.65  ? 137 HIS C CD2 1 
ATOM   8260  C CE1 . HIS C 1 137 ? 13.585  -1.485  -8.542  1.00 33.38  ? 137 HIS C CE1 1 
ATOM   8261  N NE2 . HIS C 1 137 ? 13.732  -1.534  -9.874  1.00 31.02  ? 137 HIS C NE2 1 
ATOM   8262  N N   . PRO C 1 138 ? 10.733  -3.725  -7.152  1.00 35.51  ? 138 PRO C N   1 
ATOM   8263  C CA  . PRO C 1 138 ? 10.888  -4.104  -5.755  1.00 32.61  ? 138 PRO C CA  1 
ATOM   8264  C C   . PRO C 1 138 ? 11.243  -2.961  -4.823  1.00 32.24  ? 138 PRO C C   1 
ATOM   8265  O O   . PRO C 1 138 ? 10.940  -3.064  -3.642  1.00 31.33  ? 138 PRO C O   1 
ATOM   8266  C CB  . PRO C 1 138 ? 11.994  -5.158  -5.775  1.00 34.60  ? 138 PRO C CB  1 
ATOM   8267  C CG  . PRO C 1 138 ? 12.735  -4.865  -7.080  1.00 37.81  ? 138 PRO C CG  1 
ATOM   8268  C CD  . PRO C 1 138 ? 11.641  -4.460  -8.049  1.00 35.14  ? 138 PRO C CD  1 
ATOM   8269  N N   . MET C 1 139 ? 11.831  -1.882  -5.353  1.00 32.58  ? 139 MET C N   1 
ATOM   8270  C CA  . MET C 1 139 ? 12.153  -0.713  -4.532  1.00 32.89  ? 139 MET C CA  1 
ATOM   8271  C C   . MET C 1 139 ? 10.906  0.130   -4.248  1.00 35.43  ? 139 MET C C   1 
ATOM   8272  O O   . MET C 1 139 ? 10.809  0.747   -3.199  1.00 33.46  ? 139 MET C O   1 
ATOM   8273  C CB  . MET C 1 139 ? 13.212  0.163   -5.188  1.00 34.39  ? 139 MET C CB  1 
ATOM   8274  C CG  . MET C 1 139 ? 14.638  -0.285  -4.944  1.00 31.19  ? 139 MET C CG  1 
ATOM   8275  S SD  . MET C 1 139 ? 15.105  -0.280  -3.209  1.00 35.49  ? 139 MET C SD  1 
ATOM   8276  C CE  . MET C 1 139 ? 15.072  1.471   -2.841  1.00 38.44  ? 139 MET C CE  1 
ATOM   8277  N N   . THR C 1 140 ? 9.932   0.133   -5.164  1.00 34.41  ? 140 THR C N   1 
ATOM   8278  C CA  . THR C 1 140 ? 8.635   0.767   -4.950  1.00 30.75  ? 140 THR C CA  1 
ATOM   8279  C C   . THR C 1 140 ? 7.871   0.005   -3.878  1.00 31.77  ? 140 THR C C   1 
ATOM   8280  O O   . THR C 1 140 ? 7.319   0.603   -2.957  1.00 29.58  ? 140 THR C O   1 
ATOM   8281  C CB  . THR C 1 140 ? 7.842   0.781   -6.251  1.00 28.87  ? 140 THR C CB  1 
ATOM   8282  O OG1 . THR C 1 140 ? 8.592   1.547   -7.176  1.00 31.47  ? 140 THR C OG1 1 
ATOM   8283  C CG2 . THR C 1 140 ? 6.461   1.362   -6.168  1.00 28.68  ? 140 THR C CG2 1 
ATOM   8284  N N   . MET C 1 141 ? 7.899   -1.328  -3.956  1.00 32.06  ? 141 MET C N   1 
ATOM   8285  C CA  . MET C 1 141 ? 7.312   -2.152  -2.914  1.00 29.25  ? 141 MET C CA  1 
ATOM   8286  C C   . MET C 1 141 ? 7.973   -1.903  -1.555  1.00 31.49  ? 141 MET C C   1 
ATOM   8287  O O   . MET C 1 141 ? 7.293   -1.931  -0.530  1.00 31.20  ? 141 MET C O   1 
ATOM   8288  C CB  . MET C 1 141 ? 7.471   -3.638  -3.208  1.00 30.86  ? 141 MET C CB  1 
ATOM   8289  C CG  . MET C 1 141 ? 6.585   -4.114  -4.280  1.00 33.11  ? 141 MET C CG  1 
ATOM   8290  S SD  . MET C 1 141 ? 6.888   -5.850  -4.541  1.00 35.28  ? 141 MET C SD  1 
ATOM   8291  C CE  . MET C 1 141 ? 5.804   -6.112  -5.933  1.00 36.27  ? 141 MET C CE  1 
ATOM   8292  N N   . PHE C 1 142 ? 9.308   -1.798  -1.544  1.00 30.18  ? 142 PHE C N   1 
ATOM   8293  C CA  . PHE C 1 142 ? 10.063  -1.652  -0.329  1.00 28.61  ? 142 PHE C CA  1 
ATOM   8294  C C   . PHE C 1 142 ? 9.733   -0.319  0.345   1.00 32.97  ? 142 PHE C C   1 
ATOM   8295  O O   . PHE C 1 142 ? 9.480   -0.275  1.556   1.00 31.78  ? 142 PHE C O   1 
ATOM   8296  C CB  . PHE C 1 142 ? 11.556  -1.795  -0.641  1.00 31.85  ? 142 PHE C CB  1 
ATOM   8297  C CG  . PHE C 1 142 ? 12.457  -1.874  0.573   1.00 31.57  ? 142 PHE C CG  1 
ATOM   8298  C CD1 . PHE C 1 142 ? 12.248  -2.835  1.542   1.00 29.59  ? 142 PHE C CD1 1 
ATOM   8299  C CD2 . PHE C 1 142 ? 13.522  -1.001  0.718   1.00 31.51  ? 142 PHE C CD2 1 
ATOM   8300  C CE1 . PHE C 1 142 ? 13.079  -2.912  2.646   1.00 31.92  ? 142 PHE C CE1 1 
ATOM   8301  C CE2 . PHE C 1 142 ? 14.374  -1.097  1.803   1.00 32.78  ? 142 PHE C CE2 1 
ATOM   8302  C CZ  . PHE C 1 142 ? 14.131  -2.031  2.785   1.00 31.64  ? 142 PHE C CZ  1 
ATOM   8303  N N   . ALA C 1 143 ? 9.763   0.763   -0.431  1.00 30.73  ? 143 ALA C N   1 
ATOM   8304  C CA  . ALA C 1 143 ? 9.409   2.078   0.076   1.00 34.30  ? 143 ALA C CA  1 
ATOM   8305  C C   . ALA C 1 143 ? 7.994   2.080   0.665   1.00 35.23  ? 143 ALA C C   1 
ATOM   8306  O O   . ALA C 1 143 ? 7.778   2.625   1.744   1.00 40.62  ? 143 ALA C O   1 
ATOM   8307  C CB  . ALA C 1 143 ? 9.568   3.134   -1.003  1.00 29.65  ? 143 ALA C CB  1 
ATOM   8308  N N   . ALA C 1 144 ? 7.056   1.447   -0.038  1.00 34.72  ? 144 ALA C N   1 
ATOM   8309  C CA  . ALA C 1 144 ? 5.655   1.400   0.331   1.00 34.65  ? 144 ALA C CA  1 
ATOM   8310  C C   . ALA C 1 144 ? 5.419   0.619   1.613   1.00 33.43  ? 144 ALA C C   1 
ATOM   8311  O O   . ALA C 1 144 ? 4.617   1.042   2.439   1.00 33.46  ? 144 ALA C O   1 
ATOM   8312  C CB  . ALA C 1 144 ? 4.869   0.786   -0.784  1.00 36.99  ? 144 ALA C CB  1 
ATOM   8313  N N   . GLY C 1 145 ? 6.130   -0.497  1.782   1.00 33.72  ? 145 GLY C N   1 
ATOM   8314  C CA  . GLY C 1 145 ? 6.004   -1.318  2.984   1.00 31.59  ? 145 GLY C CA  1 
ATOM   8315  C C   . GLY C 1 145 ? 6.423   -0.533  4.232   1.00 38.30  ? 145 GLY C C   1 
ATOM   8316  O O   . GLY C 1 145 ? 5.723   -0.515  5.232   1.00 39.20  ? 145 GLY C O   1 
ATOM   8317  N N   . ILE C 1 146 ? 7.561   0.151   4.131   1.00 34.20  ? 146 ILE C N   1 
ATOM   8318  C CA  . ILE C 1 146 ? 8.113   0.968   5.190   1.00 36.01  ? 146 ILE C CA  1 
ATOM   8319  C C   . ILE C 1 146 ? 7.151   2.103   5.527   1.00 38.27  ? 146 ILE C C   1 
ATOM   8320  O O   . ILE C 1 146 ? 6.809   2.293   6.684   1.00 35.48  ? 146 ILE C O   1 
ATOM   8321  C CB  . ILE C 1 146 ? 9.484   1.521   4.780   1.00 36.45  ? 146 ILE C CB  1 
ATOM   8322  C CG1 . ILE C 1 146 ? 10.495  0.415   4.474   1.00 37.66  ? 146 ILE C CG1 1 
ATOM   8323  C CG2 . ILE C 1 146 ? 10.018  2.426   5.848   1.00 39.75  ? 146 ILE C CG2 1 
ATOM   8324  C CD1 . ILE C 1 146 ? 11.644  0.920   3.636   1.00 37.21  ? 146 ILE C CD1 1 
ATOM   8325  N N   . LEU C 1 147 ? 6.710   2.846   4.511   1.00 35.03  ? 147 LEU C N   1 
ATOM   8326  C CA  . LEU C 1 147 ? 5.802   3.948   4.746   1.00 33.29  ? 147 LEU C CA  1 
ATOM   8327  C C   . LEU C 1 147 ? 4.536   3.487   5.463   1.00 35.84  ? 147 LEU C C   1 
ATOM   8328  O O   . LEU C 1 147 ? 4.072   4.176   6.355   1.00 35.44  ? 147 LEU C O   1 
ATOM   8329  C CB  . LEU C 1 147 ? 5.454   4.600   3.416   1.00 34.25  ? 147 LEU C CB  1 
ATOM   8330  C CG  . LEU C 1 147 ? 4.505   5.786   3.476   1.00 38.67  ? 147 LEU C CG  1 
ATOM   8331  C CD1 . LEU C 1 147 ? 4.962   6.811   4.511   1.00 44.26  ? 147 LEU C CD1 1 
ATOM   8332  C CD2 . LEU C 1 147 ? 4.383   6.424   2.093   1.00 36.21  ? 147 LEU C CD2 1 
ATOM   8333  N N   . ALA C 1 148 ? 3.951   2.352   5.073   1.00 37.62  ? 148 ALA C N   1 
ATOM   8334  C CA  . ALA C 1 148 ? 2.684   1.941   5.678   1.00 37.87  ? 148 ALA C CA  1 
ATOM   8335  C C   . ALA C 1 148 ? 2.831   1.777   7.199   1.00 34.92  ? 148 ALA C C   1 
ATOM   8336  O O   . ALA C 1 148 ? 1.889   2.007   7.942   1.00 31.97  ? 148 ALA C O   1 
ATOM   8337  C CB  . ALA C 1 148 ? 2.200   0.677   5.056   1.00 31.13  ? 148 ALA C CB  1 
ATOM   8338  N N   . MET C 1 149 ? 4.038   1.455   7.648   1.00 32.25  ? 149 MET C N   1 
ATOM   8339  C CA  . MET C 1 149 ? 4.279   1.161   9.041   1.00 35.16  ? 149 MET C CA  1 
ATOM   8340  C C   . MET C 1 149 ? 4.520   2.433   9.846   1.00 36.47  ? 149 MET C C   1 
ATOM   8341  O O   . MET C 1 149 ? 4.741   2.339   11.044  1.00 33.38  ? 149 MET C O   1 
ATOM   8342  C CB  . MET C 1 149 ? 5.494   0.268   9.123   1.00 37.13  ? 149 MET C CB  1 
ATOM   8343  C CG  . MET C 1 149 ? 5.740   -0.333  10.453  1.00 35.10  ? 149 MET C CG  1 
ATOM   8344  S SD  . MET C 1 149 ? 7.010   -1.634  10.239  1.00 40.29  ? 149 MET C SD  1 
ATOM   8345  C CE  . MET C 1 149 ? 7.173   -2.080  11.979  1.00 38.35  ? 149 MET C CE  1 
ATOM   8346  N N   . GLN C 1 150 ? 4.446   3.603   9.180   1.00 31.26  ? 150 GLN C N   1 
ATOM   8347  C CA  . GLN C 1 150 ? 4.480   4.901   9.829   1.00 35.50  ? 150 GLN C CA  1 
ATOM   8348  C C   . GLN C 1 150 ? 3.349   5.050   10.856  1.00 38.92  ? 150 GLN C C   1 
ATOM   8349  O O   . GLN C 1 150 ? 3.480   5.798   11.825  1.00 34.49  ? 150 GLN C O   1 
ATOM   8350  C CB  . GLN C 1 150 ? 4.393   6.017   8.776   1.00 34.62  ? 150 GLN C CB  1 
ATOM   8351  C CG  . GLN C 1 150 ? 4.413   7.417   9.355   1.00 33.00  ? 150 GLN C CG  1 
ATOM   8352  C CD  . GLN C 1 150 ? 3.134   7.909   10.012  1.00 38.47  ? 150 GLN C CD  1 
ATOM   8353  O OE1 . GLN C 1 150 ? 2.010   7.557   9.630   1.00 30.62  ? 150 GLN C OE1 1 
ATOM   8354  N NE2 . GLN C 1 150 ? 3.307   8.849   10.935  1.00 32.44  ? 150 GLN C NE2 1 
ATOM   8355  N N   . ARG C 1 151 ? 2.240   4.335   10.664  1.00 38.60  ? 151 ARG C N   1 
ATOM   8356  C CA  . ARG C 1 151 ? 1.201   4.296   11.682  1.00 43.61  ? 151 ARG C CA  1 
ATOM   8357  C C   . ARG C 1 151 ? 1.758   3.892   13.059  1.00 38.93  ? 151 ARG C C   1 
ATOM   8358  O O   . ARG C 1 151 ? 1.161   4.206   14.084  1.00 38.74  ? 151 ARG C O   1 
ATOM   8359  C CB  . ARG C 1 151 ? 0.080   3.340   11.236  1.00 42.96  ? 151 ARG C CB  1 
ATOM   8360  C CG  . ARG C 1 151 ? -1.025  3.089   12.272  1.00 42.25  ? 151 ARG C CG  1 
ATOM   8361  C CD  . ARG C 1 151 ? -1.962  1.965   11.867  1.00 49.88  ? 151 ARG C CD  1 
ATOM   8362  N NE  . ARG C 1 151 ? -3.150  1.840   12.701  1.00 50.84  ? 151 ARG C NE  1 
ATOM   8363  C CZ  . ARG C 1 151 ? -3.282  1.020   13.740  1.00 41.44  ? 151 ARG C CZ  1 
ATOM   8364  N NH1 . ARG C 1 151 ? -2.238  0.327   14.167  1.00 35.90  ? 151 ARG C NH1 1 
ATOM   8365  N NH2 . ARG C 1 151 ? -4.442  0.947   14.387  1.00 38.04  ? 151 ARG C NH2 1 
ATOM   8366  N N   . GLU C 1 152 ? 2.838   3.111   13.113  1.00 38.60  ? 152 GLU C N   1 
ATOM   8367  C CA  . GLU C 1 152 ? 3.330   2.647   14.403  1.00 38.97  ? 152 GLU C CA  1 
ATOM   8368  C C   . GLU C 1 152 ? 4.366   3.598   14.966  1.00 34.58  ? 152 GLU C C   1 
ATOM   8369  O O   . GLU C 1 152 ? 5.079   3.205   15.869  1.00 40.13  ? 152 GLU C O   1 
ATOM   8370  C CB  . GLU C 1 152 ? 3.947   1.246   14.297  1.00 40.78  ? 152 GLU C CB  1 
ATOM   8371  C CG  . GLU C 1 152 ? 3.007   0.202   13.691  1.00 40.72  ? 152 GLU C CG  1 
ATOM   8372  C CD  . GLU C 1 152 ? 1.592   0.150   14.261  1.00 43.99  ? 152 GLU C CD  1 
ATOM   8373  O OE1 . GLU C 1 152 ? 0.637   0.178   13.446  1.00 35.12  ? 152 GLU C OE1 1 
ATOM   8374  O OE2 . GLU C 1 152 ? 1.443   0.147   15.526  1.00 42.91  ? 152 GLU C OE2 1 
ATOM   8375  N N   . SER C 1 153 ? 4.454   4.827   14.442  1.00 37.28  ? 153 SER C N   1 
ATOM   8376  C CA  . SER C 1 153 ? 5.531   5.731   14.806  1.00 39.02  ? 153 SER C CA  1 
ATOM   8377  C C   . SER C 1 153 ? 5.325   6.238   16.224  1.00 39.91  ? 153 SER C C   1 
ATOM   8378  O O   . SER C 1 153 ? 4.380   6.962   16.465  1.00 37.59  ? 153 SER C O   1 
ATOM   8379  C CB  . SER C 1 153 ? 5.619   6.918   13.892  1.00 41.25  ? 153 SER C CB  1 
ATOM   8380  O OG  . SER C 1 153 ? 6.743   7.728   14.219  1.00 36.61  ? 153 SER C OG  1 
ATOM   8381  N N   . VAL C 1 154 ? 6.271   5.930   17.105  1.00 41.79  ? 154 VAL C N   1 
ATOM   8382  C CA  . VAL C 1 154 ? 6.292   6.455   18.454  1.00 43.20  ? 154 VAL C CA  1 
ATOM   8383  C C   . VAL C 1 154 ? 6.584   7.949   18.384  1.00 43.04  ? 154 VAL C C   1 
ATOM   8384  O O   . VAL C 1 154 ? 5.953   8.769   19.037  1.00 38.28  ? 154 VAL C O   1 
ATOM   8385  C CB  . VAL C 1 154 ? 7.356   5.690   19.261  1.00 52.47  ? 154 VAL C CB  1 
ATOM   8386  C CG1 . VAL C 1 154 ? 7.549   6.257   20.654  1.00 55.03  ? 154 VAL C CG1 1 
ATOM   8387  C CG2 . VAL C 1 154 ? 7.026   4.205   19.330  1.00 54.07  ? 154 VAL C CG2 1 
ATOM   8388  N N   . PHE C 1 155 ? 7.545   8.326   17.547  1.00 46.67  ? 155 PHE C N   1 
ATOM   8389  C CA  . PHE C 1 155 ? 7.903   9.722   17.455  1.00 38.57  ? 155 PHE C CA  1 
ATOM   8390  C C   . PHE C 1 155 ? 6.714   10.531  16.990  1.00 38.19  ? 155 PHE C C   1 
ATOM   8391  O O   . PHE C 1 155 ? 6.527   11.637  17.477  1.00 46.65  ? 155 PHE C O   1 
ATOM   8392  C CB  . PHE C 1 155 ? 9.084   9.920   16.528  1.00 40.43  ? 155 PHE C CB  1 
ATOM   8393  C CG  . PHE C 1 155 ? 9.559   11.341  16.392  1.00 42.43  ? 155 PHE C CG  1 
ATOM   8394  C CD1 . PHE C 1 155 ? 8.888   12.242  15.589  1.00 38.05  ? 155 PHE C CD1 1 
ATOM   8395  C CD2 . PHE C 1 155 ? 10.708  11.764  17.040  1.00 42.65  ? 155 PHE C CD2 1 
ATOM   8396  C CE1 . PHE C 1 155 ? 9.357   13.534  15.421  1.00 41.05  ? 155 PHE C CE1 1 
ATOM   8397  C CE2 . PHE C 1 155 ? 11.168  13.060  16.876  1.00 42.81  ? 155 PHE C CE2 1 
ATOM   8398  C CZ  . PHE C 1 155 ? 10.494  13.944  16.069  1.00 42.41  ? 155 PHE C CZ  1 
ATOM   8399  N N   . ALA C 1 156 ? 5.956   10.042  16.004  1.00 36.21  ? 156 ALA C N   1 
ATOM   8400  C CA  . ALA C 1 156 ? 4.826   10.841  15.534  1.00 40.73  ? 156 ALA C CA  1 
ATOM   8401  C C   . ALA C 1 156 ? 3.757   10.964  16.634  1.00 44.77  ? 156 ALA C C   1 
ATOM   8402  O O   . ALA C 1 156 ? 3.127   12.007  16.799  1.00 43.28  ? 156 ALA C O   1 
ATOM   8403  C CB  . ALA C 1 156 ? 4.267   10.275  14.248  1.00 39.35  ? 156 ALA C CB  1 
ATOM   8404  N N   . LYS C 1 157 ? 3.585   9.902   17.419  1.00 43.28  ? 157 LYS C N   1 
ATOM   8405  C CA  . LYS C 1 157 ? 2.564   9.840   18.449  1.00 46.86  ? 157 LYS C CA  1 
ATOM   8406  C C   . LYS C 1 157 ? 2.899   10.796  19.598  1.00 47.65  ? 157 LYS C C   1 
ATOM   8407  O O   . LYS C 1 157 ? 2.055   11.584  20.005  1.00 45.67  ? 157 LYS C O   1 
ATOM   8408  C CB  . LYS C 1 157 ? 2.473   8.381   18.906  1.00 56.85  ? 157 LYS C CB  1 
ATOM   8409  C CG  . LYS C 1 157 ? 1.280   8.014   19.785  1.00 68.78  ? 157 LYS C CG  1 
ATOM   8410  C CD  . LYS C 1 157 ? 1.396   6.609   20.433  1.00 85.57  ? 157 LYS C CD  1 
ATOM   8411  C CE  . LYS C 1 157 ? 1.796   5.470   19.498  1.00 104.12 ? 157 LYS C CE  1 
ATOM   8412  N NZ  . LYS C 1 157 ? 0.739   5.062   18.530  1.00 100.01 ? 157 LYS C NZ  1 
ATOM   8413  N N   . ARG C 1 158 ? 4.136   10.716  20.106  1.00 47.82  ? 158 ARG C N   1 
ATOM   8414  C CA  . ARG C 1 158 ? 4.608   11.493  21.237  1.00 47.81  ? 158 ARG C CA  1 
ATOM   8415  C C   . ARG C 1 158 ? 4.625   12.979  20.877  1.00 49.14  ? 158 ARG C C   1 
ATOM   8416  O O   . ARG C 1 158 ? 4.341   13.832  21.712  1.00 52.68  ? 158 ARG C O   1 
ATOM   8417  C CB  . ARG C 1 158 ? 6.014   11.049  21.668  1.00 45.18  ? 158 ARG C CB  1 
ATOM   8418  C CG  . ARG C 1 158 ? 6.080   9.698   22.361  1.00 52.73  ? 158 ARG C CG  1 
ATOM   8419  C CD  . ARG C 1 158 ? 5.316   9.620   23.679  1.00 64.28  ? 158 ARG C CD  1 
ATOM   8420  N NE  . ARG C 1 158 ? 5.870   10.486  24.710  1.00 70.23  ? 158 ARG C NE  1 
ATOM   8421  C CZ  . ARG C 1 158 ? 5.246   11.526  25.266  1.00 70.06  ? 158 ARG C CZ  1 
ATOM   8422  N NH1 . ARG C 1 158 ? 5.955   12.410  25.944  1.00 77.97  ? 158 ARG C NH1 1 
ATOM   8423  N NH2 . ARG C 1 158 ? 3.952   11.740  25.078  1.00 62.18  ? 158 ARG C NH2 1 
ATOM   8424  N N   . TYR C 1 159 ? 4.925   13.284  19.623  1.00 42.35  ? 159 TYR C N   1 
ATOM   8425  C CA  . TYR C 1 159 ? 4.975   14.662  19.193  1.00 43.41  ? 159 TYR C CA  1 
ATOM   8426  C C   . TYR C 1 159 ? 3.583   15.270  19.234  1.00 48.67  ? 159 TYR C C   1 
ATOM   8427  O O   . TYR C 1 159 ? 3.457   16.403  19.681  1.00 54.90  ? 159 TYR C O   1 
ATOM   8428  C CB  . TYR C 1 159 ? 5.568   14.808  17.786  1.00 45.77  ? 159 TYR C CB  1 
ATOM   8429  C CG  . TYR C 1 159 ? 5.703   16.253  17.371  1.00 45.91  ? 159 TYR C CG  1 
ATOM   8430  C CD1 . TYR C 1 159 ? 6.839   16.978  17.686  1.00 43.53  ? 159 TYR C CD1 1 
ATOM   8431  C CD2 . TYR C 1 159 ? 4.648   16.931  16.786  1.00 45.83  ? 159 TYR C CD2 1 
ATOM   8432  C CE1 . TYR C 1 159 ? 6.939   18.330  17.393  1.00 44.69  ? 159 TYR C CE1 1 
ATOM   8433  C CE2 . TYR C 1 159 ? 4.740   18.279  16.463  1.00 51.48  ? 159 TYR C CE2 1 
ATOM   8434  C CZ  . TYR C 1 159 ? 5.888   18.985  16.785  1.00 49.83  ? 159 TYR C CZ  1 
ATOM   8435  O OH  . TYR C 1 159 ? 6.012   20.319  16.474  1.00 56.65  ? 159 TYR C OH  1 
ATOM   8436  N N   . GLU C 1 160 ? 2.565   14.553  18.714  1.00 55.55  ? 160 GLU C N   1 
ATOM   8437  C CA  . GLU C 1 160 ? 1.173   15.008  18.793  1.00 59.82  ? 160 GLU C CA  1 
ATOM   8438  C C   . GLU C 1 160 ? 0.773   15.264  20.255  1.00 57.42  ? 160 GLU C C   1 
ATOM   8439  O O   . GLU C 1 160 ? 0.267   16.342  20.566  1.00 51.31  ? 160 GLU C O   1 
ATOM   8440  C CB  . GLU C 1 160 ? 0.171   14.000  18.217  1.00 66.75  ? 160 GLU C CB  1 
ATOM   8441  C CG  . GLU C 1 160 ? 0.374   13.624  16.748  1.00 88.78  ? 160 GLU C CG  1 
ATOM   8442  C CD  . GLU C 1 160 ? -0.579  14.213  15.713  1.00 103.66 ? 160 GLU C CD  1 
ATOM   8443  O OE1 . GLU C 1 160 ? -1.163  15.286  16.004  1.00 106.05 ? 160 GLU C OE1 1 
ATOM   8444  O OE2 . GLU C 1 160 ? -0.755  13.582  14.613  1.00 87.40  ? 160 GLU C OE2 1 
ATOM   8445  N N   . GLU C 1 161 ? 1.008   14.269  21.133  1.00 48.00  ? 161 GLU C N   1 
ATOM   8446  C CA  . GLU C 1 161 ? 0.677   14.345  22.552  1.00 56.10  ? 161 GLU C CA  1 
ATOM   8447  C C   . GLU C 1 161 ? 1.435   15.461  23.272  1.00 61.80  ? 161 GLU C C   1 
ATOM   8448  O O   . GLU C 1 161 ? 1.025   15.861  24.347  1.00 65.95  ? 161 GLU C O   1 
ATOM   8449  C CB  . GLU C 1 161 ? 1.033   13.053  23.283  1.00 55.29  ? 161 GLU C CB  1 
ATOM   8450  C CG  . GLU C 1 161 ? 0.138   11.886  22.921  1.00 59.07  ? 161 GLU C CG  1 
ATOM   8451  C CD  . GLU C 1 161 ? 0.633   10.498  23.319  1.00 66.49  ? 161 GLU C CD  1 
ATOM   8452  O OE1 . GLU C 1 161 ? -0.111  9.530   23.034  1.00 72.75  ? 161 GLU C OE1 1 
ATOM   8453  O OE2 . GLU C 1 161 ? 1.758   10.370  23.896  1.00 62.55  ? 161 GLU C OE2 1 
ATOM   8454  N N   . GLY C 1 162 ? 2.540   15.950  22.696  1.00 68.98  ? 162 GLY C N   1 
ATOM   8455  C CA  . GLY C 1 162 ? 3.385   16.946  23.340  1.00 61.80  ? 162 GLY C CA  1 
ATOM   8456  C C   . GLY C 1 162 ? 4.551   16.265  24.050  1.00 60.58  ? 162 GLY C C   1 
ATOM   8457  O O   . GLY C 1 162 ? 4.352   15.386  24.876  1.00 73.02  ? 162 GLY C O   1 
ATOM   8458  N N   . MET C 1 163 ? 5.769   16.596  23.639  1.00 60.67  ? 163 MET C N   1 
ATOM   8459  C CA  . MET C 1 163 ? 6.968   16.030  24.236  1.00 56.35  ? 163 MET C CA  1 
ATOM   8460  C C   . MET C 1 163 ? 8.062   17.082  24.066  1.00 54.13  ? 163 MET C C   1 
ATOM   8461  O O   . MET C 1 163 ? 8.052   17.849  23.103  1.00 55.76  ? 163 MET C O   1 
ATOM   8462  C CB  . MET C 1 163 ? 7.370   14.689  23.590  1.00 57.96  ? 163 MET C CB  1 
ATOM   8463  C CG  . MET C 1 163 ? 8.166   14.797  22.272  1.00 56.85  ? 163 MET C CG  1 
ATOM   8464  S SD  . MET C 1 163 ? 8.888   13.233  21.679  1.00 53.80  ? 163 MET C SD  1 
ATOM   8465  C CE  . MET C 1 163 ? 8.601   13.401  19.923  1.00 56.62  ? 163 MET C CE  1 
ATOM   8466  N N   . ARG C 1 164 ? 8.974   17.158  25.027  1.00 67.93  ? 164 ARG C N   1 
ATOM   8467  C CA  . ARG C 1 164 ? 10.040  18.149  24.966  1.00 79.67  ? 164 ARG C CA  1 
ATOM   8468  C C   . ARG C 1 164 ? 11.053  17.720  23.904  1.00 64.46  ? 164 ARG C C   1 
ATOM   8469  O O   . ARG C 1 164 ? 11.174  16.544  23.595  1.00 57.51  ? 164 ARG C O   1 
ATOM   8470  C CB  . ARG C 1 164 ? 10.639  18.348  26.363  1.00 86.05  ? 164 ARG C CB  1 
ATOM   8471  C CG  . ARG C 1 164 ? 9.793   19.246  27.259  1.00 96.47  ? 164 ARG C CG  1 
ATOM   8472  C CD  . ARG C 1 164 ? 9.960   18.936  28.736  1.00 111.11 ? 164 ARG C CD  1 
ATOM   8473  N NE  . ARG C 1 164 ? 11.364  18.794  29.107  1.00 124.13 ? 164 ARG C NE  1 
ATOM   8474  C CZ  . ARG C 1 164 ? 11.926  17.673  29.556  1.00 127.17 ? 164 ARG C CZ  1 
ATOM   8475  N NH1 . ARG C 1 164 ? 11.209  16.568  29.685  1.00 114.66 ? 164 ARG C NH1 1 
ATOM   8476  N NH2 . ARG C 1 164 ? 13.213  17.663  29.868  1.00 123.95 ? 164 ARG C NH2 1 
ATOM   8477  N N   . ARG C 1 165 ? 11.787  18.683  23.352  1.00 67.28  ? 165 ARG C N   1 
ATOM   8478  C CA  . ARG C 1 165 ? 12.661  18.421  22.221  1.00 64.37  ? 165 ARG C CA  1 
ATOM   8479  C C   . ARG C 1 165 ? 13.771  17.458  22.633  1.00 62.14  ? 165 ARG C C   1 
ATOM   8480  O O   . ARG C 1 165 ? 14.381  16.842  21.763  1.00 63.25  ? 165 ARG C O   1 
ATOM   8481  C CB  . ARG C 1 165 ? 13.172  19.741  21.642  1.00 71.66  ? 165 ARG C CB  1 
ATOM   8482  C CG  . ARG C 1 165 ? 12.045  20.694  21.259  1.00 85.17  ? 165 ARG C CG  1 
ATOM   8483  C CD  . ARG C 1 165 ? 12.457  22.149  21.164  1.00 88.76  ? 165 ARG C CD  1 
ATOM   8484  N NE  . ARG C 1 165 ? 13.227  22.379  19.954  1.00 92.12  ? 165 ARG C NE  1 
ATOM   8485  C CZ  . ARG C 1 165 ? 14.367  23.068  19.898  1.00 94.93  ? 165 ARG C CZ  1 
ATOM   8486  N NH1 . ARG C 1 165 ? 14.845  23.660  20.983  1.00 95.86  ? 165 ARG C NH1 1 
ATOM   8487  N NH2 . ARG C 1 165 ? 15.011  23.184  18.747  1.00 69.92  ? 165 ARG C NH2 1 
ATOM   8488  N N   . GLU C 1 166 ? 13.964  17.290  23.950  1.00 56.88  ? 166 GLU C N   1 
ATOM   8489  C CA  . GLU C 1 166 ? 15.020  16.488  24.556  1.00 61.33  ? 166 GLU C CA  1 
ATOM   8490  C C   . GLU C 1 166 ? 14.661  14.998  24.577  1.00 63.55  ? 166 GLU C C   1 
ATOM   8491  O O   . GLU C 1 166 ? 15.508  14.166  24.889  1.00 62.12  ? 166 GLU C O   1 
ATOM   8492  C CB  . GLU C 1 166 ? 15.269  16.947  26.009  1.00 73.53  ? 166 GLU C CB  1 
ATOM   8493  C CG  . GLU C 1 166 ? 15.912  18.344  26.170  1.00 92.46  ? 166 GLU C CG  1 
ATOM   8494  C CD  . GLU C 1 166 ? 15.071  19.611  26.411  1.00 100.84 ? 166 GLU C CD  1 
ATOM   8495  O OE1 . GLU C 1 166 ? 15.676  20.698  26.572  1.00 91.40  ? 166 GLU C OE1 1 
ATOM   8496  O OE2 . GLU C 1 166 ? 13.822  19.549  26.446  1.00 107.18 ? 166 GLU C OE2 1 
ATOM   8497  N N   . GLU C 1 167 ? 13.386  14.657  24.339  1.00 60.11  ? 167 GLU C N   1 
ATOM   8498  C CA  . GLU C 1 167 ? 12.981  13.266  24.222  1.00 59.13  ? 167 GLU C CA  1 
ATOM   8499  C C   . GLU C 1 167 ? 13.042  12.811  22.759  1.00 41.53  ? 167 GLU C C   1 
ATOM   8500  O O   . GLU C 1 167 ? 12.999  11.634  22.477  1.00 44.60  ? 167 GLU C O   1 
ATOM   8501  C CB  . GLU C 1 167 ? 11.551  13.048  24.723  1.00 69.47  ? 167 GLU C CB  1 
ATOM   8502  C CG  . GLU C 1 167 ? 11.275  13.547  26.138  1.00 90.76  ? 167 GLU C CG  1 
ATOM   8503  C CD  . GLU C 1 167 ? 9.788   13.585  26.490  1.00 91.73  ? 167 GLU C CD  1 
ATOM   8504  O OE1 . GLU C 1 167 ? 9.131   12.488  26.433  1.00 72.89  ? 167 GLU C OE1 1 
ATOM   8505  O OE2 . GLU C 1 167 ? 9.268   14.720  26.764  1.00 68.72  ? 167 GLU C OE2 1 
ATOM   8506  N N   . HIS C 1 168 ? 13.114  13.727  21.812  1.00 38.84  ? 168 HIS C N   1 
ATOM   8507  C CA  . HIS C 1 168 ? 13.092  13.358  20.402  1.00 42.94  ? 168 HIS C CA  1 
ATOM   8508  C C   . HIS C 1 168 ? 13.985  12.157  20.082  1.00 42.47  ? 168 HIS C C   1 
ATOM   8509  O O   . HIS C 1 168 ? 13.553  11.207  19.435  1.00 41.77  ? 168 HIS C O   1 
ATOM   8510  C CB  . HIS C 1 168 ? 13.518  14.544  19.536  1.00 42.01  ? 168 HIS C CB  1 
ATOM   8511  C CG  . HIS C 1 168 ? 12.491  15.618  19.450  1.00 42.61  ? 168 HIS C CG  1 
ATOM   8512  N ND1 . HIS C 1 168 ? 12.627  16.692  18.592  1.00 48.24  ? 168 HIS C ND1 1 
ATOM   8513  C CD2 . HIS C 1 168 ? 11.313  15.777  20.084  1.00 41.30  ? 168 HIS C CD2 1 
ATOM   8514  C CE1 . HIS C 1 168 ? 11.555  17.483  18.733  1.00 53.53  ? 168 HIS C CE1 1 
ATOM   8515  N NE2 . HIS C 1 168 ? 10.745  16.941  19.636  1.00 41.35  ? 168 HIS C NE2 1 
ATOM   8516  N N   . TRP C 1 169 ? 15.233  12.175  20.550  1.00 40.89  ? 169 TRP C N   1 
ATOM   8517  C CA  . TRP C 1 169 ? 16.174  11.153  20.138  1.00 42.56  ? 169 TRP C CA  1 
ATOM   8518  C C   . TRP C 1 169 ? 15.753  9.779   20.646  1.00 41.28  ? 169 TRP C C   1 
ATOM   8519  O O   . TRP C 1 169 ? 16.074  8.776   20.030  1.00 45.07  ? 169 TRP C O   1 
ATOM   8520  C CB  . TRP C 1 169 ? 17.609  11.539  20.540  1.00 44.44  ? 169 TRP C CB  1 
ATOM   8521  C CG  . TRP C 1 169 ? 17.888  11.507  22.000  1.00 43.69  ? 169 TRP C CG  1 
ATOM   8522  C CD1 . TRP C 1 169 ? 17.870  12.560  22.883  1.00 43.17  ? 169 TRP C CD1 1 
ATOM   8523  C CD2 . TRP C 1 169 ? 18.223  10.338  22.753  1.00 36.99  ? 169 TRP C CD2 1 
ATOM   8524  N NE1 . TRP C 1 169 ? 18.131  12.111  24.146  1.00 36.11  ? 169 TRP C NE1 1 
ATOM   8525  C CE2 . TRP C 1 169 ? 18.361  10.758  24.099  1.00 39.26  ? 169 TRP C CE2 1 
ATOM   8526  C CE3 . TRP C 1 169 ? 18.335  8.987   22.432  1.00 36.67  ? 169 TRP C CE3 1 
ATOM   8527  C CZ2 . TRP C 1 169 ? 18.712  9.875   25.112  1.00 35.35  ? 169 TRP C CZ2 1 
ATOM   8528  C CZ3 . TRP C 1 169 ? 18.688  8.118   23.431  1.00 39.00  ? 169 TRP C CZ3 1 
ATOM   8529  C CH2 . TRP C 1 169 ? 18.864  8.559   24.748  1.00 43.28  ? 169 TRP C CH2 1 
ATOM   8530  N N   . GLU C 1 170 ? 15.082  9.732   21.790  1.00 44.42  ? 170 GLU C N   1 
ATOM   8531  C CA  . GLU C 1 170 ? 14.659  8.478   22.397  1.00 47.34  ? 170 GLU C CA  1 
ATOM   8532  C C   . GLU C 1 170 ? 13.510  7.874   21.595  1.00 39.60  ? 170 GLU C C   1 
ATOM   8533  O O   . GLU C 1 170 ? 13.361  6.666   21.500  1.00 37.54  ? 170 GLU C O   1 
ATOM   8534  C CB  . GLU C 1 170 ? 14.174  8.723   23.828  1.00 50.95  ? 170 GLU C CB  1 
ATOM   8535  C CG  . GLU C 1 170 ? 15.198  9.428   24.701  1.00 59.11  ? 170 GLU C CG  1 
ATOM   8536  C CD  . GLU C 1 170 ? 14.869  9.423   26.186  1.00 64.75  ? 170 GLU C CD  1 
ATOM   8537  O OE1 . GLU C 1 170 ? 14.897  10.508  26.790  1.00 73.33  ? 170 GLU C OE1 1 
ATOM   8538  O OE2 . GLU C 1 170 ? 14.604  8.330   26.739  1.00 68.40  ? 170 GLU C OE2 1 
ATOM   8539  N N   . ALA C 1 171 ? 12.658  8.740   21.081  1.00 37.42  ? 171 ALA C N   1 
ATOM   8540  C CA  . ALA C 1 171 ? 11.537  8.299   20.261  1.00 43.91  ? 171 ALA C CA  1 
ATOM   8541  C C   . ALA C 1 171 ? 12.067  7.811   18.906  1.00 40.44  ? 171 ALA C C   1 
ATOM   8542  O O   . ALA C 1 171 ? 11.646  6.782   18.408  1.00 44.73  ? 171 ALA C O   1 
ATOM   8543  C CB  . ALA C 1 171 ? 10.569  9.453   20.122  1.00 35.81  ? 171 ALA C CB  1 
ATOM   8544  N N   . MET C 1 172 ? 13.039  8.550   18.359  1.00 41.88  ? 172 MET C N   1 
ATOM   8545  C CA  . MET C 1 172 ? 13.725  8.211   17.120  1.00 42.92  ? 172 MET C CA  1 
ATOM   8546  C C   . MET C 1 172 ? 14.425  6.866   17.288  1.00 41.79  ? 172 MET C C   1 
ATOM   8547  O O   . MET C 1 172 ? 14.510  6.096   16.350  1.00 40.12  ? 172 MET C O   1 
ATOM   8548  C CB  . MET C 1 172 ? 14.776  9.267   16.764  1.00 38.33  ? 172 MET C CB  1 
ATOM   8549  C CG  . MET C 1 172 ? 14.217  10.558  16.241  1.00 38.87  ? 172 MET C CG  1 
ATOM   8550  S SD  . MET C 1 172 ? 13.252  10.484  14.680  1.00 47.24  ? 172 MET C SD  1 
ATOM   8551  C CE  . MET C 1 172 ? 14.332  9.546   13.607  1.00 47.13  ? 172 MET C CE  1 
ATOM   8552  N N   . LEU C 1 173 ? 14.941  6.600   18.483  1.00 41.19  ? 173 LEU C N   1 
ATOM   8553  C CA  . LEU C 1 173 ? 15.692  5.381   18.702  1.00 45.67  ? 173 LEU C CA  1 
ATOM   8554  C C   . LEU C 1 173 ? 14.726  4.206   18.779  1.00 42.75  ? 173 LEU C C   1 
ATOM   8555  O O   . LEU C 1 173 ? 15.024  3.138   18.248  1.00 44.71  ? 173 LEU C O   1 
ATOM   8556  C CB  . LEU C 1 173 ? 16.562  5.473   19.965  1.00 41.37  ? 173 LEU C CB  1 
ATOM   8557  C CG  . LEU C 1 173 ? 17.076  4.115   20.479  1.00 44.04  ? 173 LEU C CG  1 
ATOM   8558  C CD1 . LEU C 1 173 ? 18.047  3.476   19.516  1.00 41.01  ? 173 LEU C CD1 1 
ATOM   8559  C CD2 . LEU C 1 173 ? 17.768  4.224   21.840  1.00 48.43  ? 173 LEU C CD2 1 
ATOM   8560  N N   . GLU C 1 174 ? 13.589  4.404   19.452  1.00 42.42  ? 174 GLU C N   1 
ATOM   8561  C CA  . GLU C 1 174 ? 12.523  3.407   19.488  1.00 42.35  ? 174 GLU C CA  1 
ATOM   8562  C C   . GLU C 1 174 ? 12.057  3.068   18.061  1.00 35.38  ? 174 GLU C C   1 
ATOM   8563  O O   . GLU C 1 174 ? 12.114  1.932   17.648  1.00 31.60  ? 174 GLU C O   1 
ATOM   8564  C CB  . GLU C 1 174 ? 11.368  3.938   20.347  1.00 43.88  ? 174 GLU C CB  1 
ATOM   8565  C CG  . GLU C 1 174 ? 10.280  2.922   20.600  1.00 53.76  ? 174 GLU C CG  1 
ATOM   8566  C CD  . GLU C 1 174 ? 10.709  1.681   21.374  1.00 62.61  ? 174 GLU C CD  1 
ATOM   8567  O OE1 . GLU C 1 174 ? 11.827  1.671   21.960  1.00 57.67  ? 174 GLU C OE1 1 
ATOM   8568  O OE2 . GLU C 1 174 ? 9.921   0.715   21.384  1.00 69.84  ? 174 GLU C OE2 1 
ATOM   8569  N N   . ASP C 1 175 ? 11.628  4.063   17.293  1.00 33.68  ? 175 ASP C N   1 
ATOM   8570  C CA  . ASP C 1 175 ? 11.229  3.864   15.905  1.00 39.26  ? 175 ASP C CA  1 
ATOM   8571  C C   . ASP C 1 175 ? 12.318  3.197   15.071  1.00 40.73  ? 175 ASP C C   1 
ATOM   8572  O O   . ASP C 1 175 ? 11.995  2.369   14.229  1.00 38.39  ? 175 ASP C O   1 
ATOM   8573  C CB  . ASP C 1 175 ? 10.870  5.185   15.238  1.00 39.66  ? 175 ASP C CB  1 
ATOM   8574  C CG  . ASP C 1 175 ? 9.515   5.667   15.702  1.00 39.27  ? 175 ASP C CG  1 
ATOM   8575  O OD1 . ASP C 1 175 ? 8.803   4.841   16.273  1.00 43.47  ? 175 ASP C OD1 1 
ATOM   8576  O OD2 . ASP C 1 175 ? 9.196   6.851   15.487  1.00 42.40  ? 175 ASP C OD2 1 
ATOM   8577  N N   . SER C 1 176 ? 13.590  3.538   15.325  1.00 38.92  ? 176 SER C N   1 
ATOM   8578  C CA  . SER C 1 176 ? 14.706  2.966   14.588  1.00 37.02  ? 176 SER C CA  1 
ATOM   8579  C C   . SER C 1 176 ? 14.829  1.478   14.877  1.00 38.27  ? 176 SER C C   1 
ATOM   8580  O O   . SER C 1 176 ? 15.081  0.698   13.967  1.00 43.51  ? 176 SER C O   1 
ATOM   8581  C CB  . SER C 1 176 ? 15.993  3.710   14.846  1.00 35.10  ? 176 SER C CB  1 
ATOM   8582  O OG  . SER C 1 176 ? 16.010  4.963   14.161  1.00 31.13  ? 176 SER C OG  1 
ATOM   8583  N N   . LEU C 1 177 ? 14.610  1.063   16.128  1.00 40.57  ? 177 LEU C N   1 
ATOM   8584  C CA  . LEU C 1 177 ? 14.777  -0.338  16.467  1.00 41.22  ? 177 LEU C CA  1 
ATOM   8585  C C   . LEU C 1 177 ? 13.686  -1.167  15.776  1.00 37.41  ? 177 LEU C C   1 
ATOM   8586  O O   . LEU C 1 177 ? 13.936  -2.259  15.296  1.00 38.68  ? 177 LEU C O   1 
ATOM   8587  C CB  . LEU C 1 177 ? 14.743  -0.522  17.993  1.00 45.48  ? 177 LEU C CB  1 
ATOM   8588  C CG  . LEU C 1 177 ? 15.959  -0.043  18.793  1.00 47.45  ? 177 LEU C CG  1 
ATOM   8589  C CD1 . LEU C 1 177 ? 15.682  -0.133  20.290  1.00 48.20  ? 177 LEU C CD1 1 
ATOM   8590  C CD2 . LEU C 1 177 ? 17.212  -0.841  18.460  1.00 43.95  ? 177 LEU C CD2 1 
ATOM   8591  N N   . ASN C 1 178 ? 12.461  -0.663  15.749  1.00 35.76  ? 178 ASN C N   1 
ATOM   8592  C CA  . ASN C 1 178 ? 11.363  -1.385  15.131  1.00 37.05  ? 178 ASN C CA  1 
ATOM   8593  C C   . ASN C 1 178 ? 11.556  -1.448  13.616  1.00 38.35  ? 178 ASN C C   1 
ATOM   8594  O O   . ASN C 1 178 ? 11.306  -2.464  12.997  1.00 34.44  ? 178 ASN C O   1 
ATOM   8595  C CB  . ASN C 1 178 ? 10.013  -0.761  15.479  1.00 38.57  ? 178 ASN C CB  1 
ATOM   8596  C CG  . ASN C 1 178 ? 9.685   -0.843  16.961  1.00 37.97  ? 178 ASN C CG  1 
ATOM   8597  O OD1 . ASN C 1 178 ? 10.071  -1.772  17.666  1.00 34.43  ? 178 ASN C OD1 1 
ATOM   8598  N ND2 . ASN C 1 178 ? 8.898   0.097   17.413  1.00 35.63  ? 178 ASN C ND2 1 
ATOM   8599  N N   . MET C 1 179 ? 11.926  -0.333  13.003  1.00 33.22  ? 179 MET C N   1 
ATOM   8600  C CA  . MET C 1 179 ? 11.938  -0.299  11.560  1.00 35.50  ? 179 MET C CA  1 
ATOM   8601  C C   . MET C 1 179 ? 13.093  -1.160  11.071  1.00 35.60  ? 179 MET C C   1 
ATOM   8602  O O   . MET C 1 179 ? 12.912  -1.911  10.132  1.00 41.62  ? 179 MET C O   1 
ATOM   8603  C CB  . MET C 1 179 ? 12.044  1.126   11.011  1.00 35.44  ? 179 MET C CB  1 
ATOM   8604  C CG  . MET C 1 179 ? 12.129  1.158   9.507   1.00 37.80  ? 179 MET C CG  1 
ATOM   8605  S SD  . MET C 1 179 ? 12.507  2.795   8.888   1.00 36.29  ? 179 MET C SD  1 
ATOM   8606  C CE  . MET C 1 179 ? 14.294  2.705   8.844   1.00 39.11  ? 179 MET C CE  1 
ATOM   8607  N N   . LEU C 1 180 ? 14.260  -1.095  11.725  1.00 36.57  ? 180 LEU C N   1 
ATOM   8608  C CA  . LEU C 1 180 ? 15.386  -1.912  11.307  1.00 36.50  ? 180 LEU C CA  1 
ATOM   8609  C C   . LEU C 1 180 ? 15.020  -3.390  11.421  1.00 40.52  ? 180 LEU C C   1 
ATOM   8610  O O   . LEU C 1 180 ? 15.407  -4.196  10.569  1.00 37.67  ? 180 LEU C O   1 
ATOM   8611  C CB  . LEU C 1 180 ? 16.632  -1.622  12.152  1.00 37.96  ? 180 LEU C CB  1 
ATOM   8612  C CG  . LEU C 1 180 ? 17.328  -0.307  11.847  1.00 41.75  ? 180 LEU C CG  1 
ATOM   8613  C CD1 . LEU C 1 180 ? 18.220  0.095   12.999  1.00 41.09  ? 180 LEU C CD1 1 
ATOM   8614  C CD2 . LEU C 1 180 ? 18.138  -0.405  10.550  1.00 43.99  ? 180 LEU C CD2 1 
ATOM   8615  N N   . ALA C 1 181 ? 14.351  -3.769  12.514  1.00 33.19  ? 181 ALA C N   1 
ATOM   8616  C CA  . ALA C 1 181 ? 14.005  -5.161  12.695  1.00 33.67  ? 181 ALA C CA  1 
ATOM   8617  C C   . ALA C 1 181 ? 13.023  -5.582  11.589  1.00 38.40  ? 181 ALA C C   1 
ATOM   8618  O O   . ALA C 1 181 ? 13.068  -6.706  11.107  1.00 39.39  ? 181 ALA C O   1 
ATOM   8619  C CB  . ALA C 1 181 ? 13.430  -5.339  14.083  1.00 37.14  ? 181 ALA C CB  1 
ATOM   8620  N N   . ALA C 1 182 ? 12.159  -4.658  11.145  1.00 34.02  ? 182 ALA C N   1 
ATOM   8621  C CA  . ALA C 1 182 ? 11.195  -4.949  10.096  1.00 38.02  ? 182 ALA C CA  1 
ATOM   8622  C C   . ALA C 1 182 ? 11.829  -5.068  8.696   1.00 38.89  ? 182 ALA C C   1 
ATOM   8623  O O   . ALA C 1 182 ? 11.281  -5.740  7.836   1.00 37.08  ? 182 ALA C O   1 
ATOM   8624  C CB  . ALA C 1 182 ? 10.159  -3.886  10.103  1.00 30.13  ? 182 ALA C CB  1 
ATOM   8625  N N   . LEU C 1 183 ? 12.904  -4.330  8.415   1.00 37.95  ? 183 LEU C N   1 
ATOM   8626  C CA  . LEU C 1 183 ? 13.370  -4.170  7.035   1.00 40.01  ? 183 LEU C CA  1 
ATOM   8627  C C   . LEU C 1 183 ? 13.675  -5.518  6.390   1.00 33.06  ? 183 LEU C C   1 
ATOM   8628  O O   . LEU C 1 183 ? 13.292  -5.757  5.265   1.00 36.49  ? 183 LEU C O   1 
ATOM   8629  C CB  . LEU C 1 183 ? 14.588  -3.247  6.978   1.00 40.34  ? 183 LEU C CB  1 
ATOM   8630  C CG  . LEU C 1 183 ? 14.325  -1.774  7.277   1.00 41.00  ? 183 LEU C CG  1 
ATOM   8631  C CD1 . LEU C 1 183 ? 15.495  -0.935  6.856   1.00 42.65  ? 183 LEU C CD1 1 
ATOM   8632  C CD2 . LEU C 1 183 ? 13.070  -1.261  6.588   1.00 40.73  ? 183 LEU C CD2 1 
ATOM   8633  N N   . PRO C 1 184 ? 14.353  -6.473  7.035   1.00 34.11  ? 184 PRO C N   1 
ATOM   8634  C CA  . PRO C 1 184 ? 14.620  -7.748  6.393   1.00 34.63  ? 184 PRO C CA  1 
ATOM   8635  C C   . PRO C 1 184 ? 13.387  -8.604  6.153   1.00 38.67  ? 184 PRO C C   1 
ATOM   8636  O O   . PRO C 1 184 ? 13.345  -9.382  5.186   1.00 33.23  ? 184 PRO C O   1 
ATOM   8637  C CB  . PRO C 1 184 ? 15.596  -8.455  7.349   1.00 34.91  ? 184 PRO C CB  1 
ATOM   8638  C CG  . PRO C 1 184 ? 16.100  -7.402  8.254   1.00 35.30  ? 184 PRO C CG  1 
ATOM   8639  C CD  . PRO C 1 184 ? 15.017  -6.361  8.340   1.00 37.67  ? 184 PRO C CD  1 
ATOM   8640  N N   . VAL C 1 185 ? 12.378  -8.437  7.026   1.00 37.66  ? 185 VAL C N   1 
ATOM   8641  C CA  . VAL C 1 185 ? 11.108  -9.144  6.895   1.00 35.27  ? 185 VAL C CA  1 
ATOM   8642  C C   . VAL C 1 185 ? 10.373  -8.645  5.666   1.00 32.83  ? 185 VAL C C   1 
ATOM   8643  O O   . VAL C 1 185 ? 9.798   -9.430  4.920   1.00 38.30  ? 185 VAL C O   1 
ATOM   8644  C CB  . VAL C 1 185 ? 10.245  -9.006  8.158   1.00 33.01  ? 185 VAL C CB  1 
ATOM   8645  C CG1 . VAL C 1 185 ? 8.935   -9.725  7.988   1.00 31.49  ? 185 VAL C CG1 1 
ATOM   8646  C CG2 . VAL C 1 185 ? 10.984  -9.529  9.395   1.00 30.27  ? 185 VAL C CG2 1 
ATOM   8647  N N   . ILE C 1 186 ? 10.408  -7.328  5.473   1.00 32.80  ? 186 ILE C N   1 
ATOM   8648  C CA  . ILE C 1 186 ? 9.733   -6.703  4.357   1.00 31.05  ? 186 ILE C CA  1 
ATOM   8649  C C   . ILE C 1 186 ? 10.474  -6.986  3.047   1.00 32.78  ? 186 ILE C C   1 
ATOM   8650  O O   . ILE C 1 186 ? 9.847   -7.233  2.016   1.00 30.79  ? 186 ILE C O   1 
ATOM   8651  C CB  . ILE C 1 186 ? 9.598   -5.203  4.639   1.00 33.75  ? 186 ILE C CB  1 
ATOM   8652  C CG1 . ILE C 1 186 ? 8.663   -4.925  5.821   1.00 40.18  ? 186 ILE C CG1 1 
ATOM   8653  C CG2 . ILE C 1 186 ? 9.150   -4.456  3.394   1.00 32.50  ? 186 ILE C CG2 1 
ATOM   8654  C CD1 . ILE C 1 186 ? 8.448   -3.435  6.102   1.00 39.20  ? 186 ILE C CD1 1 
ATOM   8655  N N   . ALA C 1 187 ? 11.812  -6.879  3.082   1.00 34.01  ? 187 ALA C N   1 
ATOM   8656  C CA  . ALA C 1 187 ? 12.657  -7.186  1.943   1.00 32.60  ? 187 ALA C CA  1 
ATOM   8657  C C   . ALA C 1 187 ? 12.454  -8.637  1.498   1.00 36.32  ? 187 ALA C C   1 
ATOM   8658  O O   . ALA C 1 187 ? 12.297  -8.873  0.299   1.00 34.10  ? 187 ALA C O   1 
ATOM   8659  C CB  . ALA C 1 187 ? 14.100  -6.948  2.273   1.00 32.36  ? 187 ALA C CB  1 
ATOM   8660  N N   . ALA C 1 188 ? 12.472  -9.582  2.461   1.00 28.73  ? 188 ALA C N   1 
ATOM   8661  C CA  . ALA C 1 188 ? 12.387  -10.976 2.111   1.00 31.13  ? 188 ALA C CA  1 
ATOM   8662  C C   . ALA C 1 188 ? 11.009  -11.265 1.527   1.00 37.25  ? 188 ALA C C   1 
ATOM   8663  O O   . ALA C 1 188 ? 10.894  -12.008 0.550   1.00 34.28  ? 188 ALA C O   1 
ATOM   8664  C CB  . ALA C 1 188 ? 12.659  -11.849 3.287   1.00 31.78  ? 188 ALA C CB  1 
ATOM   8665  N N   . TYR C 1 189 ? 9.991   -10.611 2.080   1.00 32.79  ? 189 TYR C N   1 
ATOM   8666  C CA  . TYR C 1 189 ? 8.639   -10.821 1.611   1.00 30.63  ? 189 TYR C CA  1 
ATOM   8667  C C   . TYR C 1 189 ? 8.540   -10.532 0.127   1.00 31.71  ? 189 TYR C C   1 
ATOM   8668  O O   . TYR C 1 189 ? 8.048   -11.358 -0.629  1.00 36.02  ? 189 TYR C O   1 
ATOM   8669  C CB  . TYR C 1 189 ? 7.636   -9.986  2.384   1.00 30.36  ? 189 TYR C CB  1 
ATOM   8670  C CG  . TYR C 1 189 ? 6.227   -10.462 2.166   1.00 35.33  ? 189 TYR C CG  1 
ATOM   8671  C CD1 . TYR C 1 189 ? 5.733   -11.533 2.883   1.00 42.64  ? 189 TYR C CD1 1 
ATOM   8672  C CD2 . TYR C 1 189 ? 5.427   -9.932  1.173   1.00 40.62  ? 189 TYR C CD2 1 
ATOM   8673  C CE1 . TYR C 1 189 ? 4.448   -11.989 2.694   1.00 43.99  ? 189 TYR C CE1 1 
ATOM   8674  C CE2 . TYR C 1 189 ? 4.135   -10.390 0.959   1.00 38.13  ? 189 TYR C CE2 1 
ATOM   8675  C CZ  . TYR C 1 189 ? 3.647   -11.424 1.722   1.00 37.34  ? 189 TYR C CZ  1 
ATOM   8676  O OH  . TYR C 1 189 ? 2.369   -11.914 1.534   1.00 42.67  ? 189 TYR C OH  1 
ATOM   8677  N N   . ILE C 1 190 ? 9.011   -9.352  -0.263  1.00 32.58  ? 190 ILE C N   1 
ATOM   8678  C CA  . ILE C 1 190 ? 9.092   -8.937  -1.655  1.00 32.97  ? 190 ILE C CA  1 
ATOM   8679  C C   . ILE C 1 190 ? 9.886   -9.973  -2.466  1.00 35.49  ? 190 ILE C C   1 
ATOM   8680  O O   . ILE C 1 190 ? 9.466   -10.361 -3.549  1.00 35.92  ? 190 ILE C O   1 
ATOM   8681  C CB  . ILE C 1 190 ? 9.753   -7.542  -1.703  1.00 29.58  ? 190 ILE C CB  1 
ATOM   8682  C CG1 . ILE C 1 190 ? 8.831   -6.482  -1.102  1.00 33.84  ? 190 ILE C CG1 1 
ATOM   8683  C CG2 . ILE C 1 190 ? 10.234  -7.149  -3.097  1.00 31.85  ? 190 ILE C CG2 1 
ATOM   8684  C CD1 . ILE C 1 190 ? 9.569   -5.260  -0.612  1.00 32.22  ? 190 ILE C CD1 1 
ATOM   8685  N N   . TYR C 1 191 ? 11.056  -10.386 -1.954  1.00 33.07  ? 191 TYR C N   1 
ATOM   8686  C CA  . TYR C 1 191 ? 11.895  -11.363 -2.630  1.00 34.66  ? 191 TYR C CA  1 
ATOM   8687  C C   . TYR C 1 191 ? 11.124  -12.648 -2.913  1.00 30.61  ? 191 TYR C C   1 
ATOM   8688  O O   . TYR C 1 191 ? 11.139  -13.148 -4.030  1.00 31.24  ? 191 TYR C O   1 
ATOM   8689  C CB  . TYR C 1 191 ? 13.153  -11.687 -1.823  1.00 34.07  ? 191 TYR C CB  1 
ATOM   8690  C CG  . TYR C 1 191 ? 14.147  -12.571 -2.548  1.00 35.58  ? 191 TYR C CG  1 
ATOM   8691  C CD1 . TYR C 1 191 ? 14.914  -12.055 -3.578  1.00 36.74  ? 191 TYR C CD1 1 
ATOM   8692  C CD2 . TYR C 1 191 ? 14.321  -13.911 -2.219  1.00 35.04  ? 191 TYR C CD2 1 
ATOM   8693  C CE1 . TYR C 1 191 ? 15.853  -12.816 -4.240  1.00 32.72  ? 191 TYR C CE1 1 
ATOM   8694  C CE2 . TYR C 1 191 ? 15.242  -14.698 -2.901  1.00 36.18  ? 191 TYR C CE2 1 
ATOM   8695  C CZ  . TYR C 1 191 ? 15.994  -14.145 -3.921  1.00 33.51  ? 191 TYR C CZ  1 
ATOM   8696  O OH  . TYR C 1 191 ? 16.884  -14.845 -4.656  1.00 39.29  ? 191 TYR C OH  1 
ATOM   8697  N N   . ARG C 1 192 ? 10.492  -13.189 -1.885  1.00 30.65  ? 192 ARG C N   1 
ATOM   8698  C CA  . ARG C 1 192 ? 9.820   -14.467 -1.948  1.00 31.46  ? 192 ARG C CA  1 
ATOM   8699  C C   . ARG C 1 192 ? 8.633   -14.371 -2.887  1.00 33.84  ? 192 ARG C C   1 
ATOM   8700  O O   . ARG C 1 192 ? 8.377   -15.286 -3.699  1.00 33.10  ? 192 ARG C O   1 
ATOM   8701  C CB  . ARG C 1 192 ? 9.313   -14.892 -0.571  1.00 35.52  ? 192 ARG C CB  1 
ATOM   8702  C CG  . ARG C 1 192 ? 10.397  -15.283 0.429   1.00 36.45  ? 192 ARG C CG  1 
ATOM   8703  C CD  . ARG C 1 192 ? 11.415  -16.334 -0.023  1.00 40.12  ? 192 ARG C CD  1 
ATOM   8704  N NE  . ARG C 1 192 ? 10.861  -17.632 -0.396  1.00 37.33  ? 192 ARG C NE  1 
ATOM   8705  C CZ  . ARG C 1 192 ? 11.593  -18.718 -0.654  1.00 40.16  ? 192 ARG C CZ  1 
ATOM   8706  N NH1 . ARG C 1 192 ? 12.908  -18.627 -0.707  1.00 44.22  ? 192 ARG C NH1 1 
ATOM   8707  N NH2 . ARG C 1 192 ? 11.027  -19.902 -0.838  1.00 36.00  ? 192 ARG C NH2 1 
ATOM   8708  N N   . ARG C 1 193 ? 7.931   -13.240 -2.791  1.00 33.84  ? 193 ARG C N   1 
ATOM   8709  C CA  . ARG C 1 193 ? 6.712   -13.078 -3.561  1.00 31.65  ? 193 ARG C CA  1 
ATOM   8710  C C   . ARG C 1 193 ? 7.031   -12.874 -5.041  1.00 36.15  ? 193 ARG C C   1 
ATOM   8711  O O   . ARG C 1 193 ? 6.354   -13.436 -5.887  1.00 35.61  ? 193 ARG C O   1 
ATOM   8712  C CB  . ARG C 1 193 ? 5.887   -11.909 -3.056  1.00 31.83  ? 193 ARG C CB  1 
ATOM   8713  C CG  . ARG C 1 193 ? 4.610   -11.721 -3.858  1.00 33.18  ? 193 ARG C CG  1 
ATOM   8714  C CD  . ARG C 1 193 ? 3.683   -10.692 -3.261  1.00 32.26  ? 193 ARG C CD  1 
ATOM   8715  N NE  . ARG C 1 193 ? 2.496   -10.552 -4.072  1.00 32.53  ? 193 ARG C NE  1 
ATOM   8716  C CZ  . ARG C 1 193 ? 2.101   -9.430  -4.673  1.00 36.07  ? 193 ARG C CZ  1 
ATOM   8717  N NH1 . ARG C 1 193 ? 2.732   -8.288  -4.467  1.00 32.24  ? 193 ARG C NH1 1 
ATOM   8718  N NH2 . ARG C 1 193 ? 0.988   -9.444  -5.383  1.00 30.72  ? 193 ARG C NH2 1 
ATOM   8719  N N   . LYS C 1 194 ? 8.033   -12.038 -5.352  1.00 35.76  ? 194 LYS C N   1 
ATOM   8720  C CA  . LYS C 1 194 ? 8.360   -11.741 -6.737  1.00 38.98  ? 194 LYS C CA  1 
ATOM   8721  C C   . LYS C 1 194 ? 9.035   -12.949 -7.397  1.00 38.91  ? 194 LYS C C   1 
ATOM   8722  O O   . LYS C 1 194 ? 8.734   -13.263 -8.533  1.00 33.38  ? 194 LYS C O   1 
ATOM   8723  C CB  . LYS C 1 194 ? 9.254   -10.503 -6.853  1.00 37.10  ? 194 LYS C CB  1 
ATOM   8724  C CG  . LYS C 1 194 ? 8.533   -9.170  -6.780  1.00 35.61  ? 194 LYS C CG  1 
ATOM   8725  C CD  . LYS C 1 194 ? 9.435   -8.003  -7.005  1.00 33.44  ? 194 LYS C CD  1 
ATOM   8726  C CE  . LYS C 1 194 ? 9.800   -7.840  -8.461  1.00 35.00  ? 194 LYS C CE  1 
ATOM   8727  N NZ  . LYS C 1 194 ? 8.606   -7.424  -9.245  1.00 34.80  ? 194 LYS C NZ  1 
ATOM   8728  N N   . TYR C 1 195 ? 9.909   -13.658 -6.676  1.00 38.91  ? 195 TYR C N   1 
ATOM   8729  C CA  . TYR C 1 195 ? 10.907  -14.461 -7.357  1.00 37.95  ? 195 TYR C CA  1 
ATOM   8730  C C   . TYR C 1 195 ? 10.919  -15.940 -6.952  1.00 39.60  ? 195 TYR C C   1 
ATOM   8731  O O   . TYR C 1 195 ? 11.521  -16.716 -7.687  1.00 38.26  ? 195 TYR C O   1 
ATOM   8732  C CB  . TYR C 1 195 ? 12.291  -13.863 -7.120  1.00 34.26  ? 195 TYR C CB  1 
ATOM   8733  C CG  . TYR C 1 195 ? 12.414  -12.410 -7.499  1.00 36.50  ? 195 TYR C CG  1 
ATOM   8734  C CD1 . TYR C 1 195 ? 12.212  -11.968 -8.804  1.00 38.21  ? 195 TYR C CD1 1 
ATOM   8735  C CD2 . TYR C 1 195 ? 12.804  -11.477 -6.559  1.00 30.11  ? 195 TYR C CD2 1 
ATOM   8736  C CE1 . TYR C 1 195 ? 12.321  -10.616 -9.135  1.00 35.65  ? 195 TYR C CE1 1 
ATOM   8737  C CE2 . TYR C 1 195 ? 12.924  -10.140 -6.875  1.00 31.45  ? 195 TYR C CE2 1 
ATOM   8738  C CZ  . TYR C 1 195 ? 12.694  -9.701  -8.164  1.00 36.32  ? 195 TYR C CZ  1 
ATOM   8739  O OH  . TYR C 1 195 ? 12.871  -8.350  -8.380  1.00 35.44  ? 195 TYR C OH  1 
ATOM   8740  N N   . LYS C 1 196 ? 10.311  -16.343 -5.818  1.00 35.38  ? 196 LYS C N   1 
ATOM   8741  C CA  . LYS C 1 196 ? 10.482  -17.704 -5.307  1.00 34.28  ? 196 LYS C CA  1 
ATOM   8742  C C   . LYS C 1 196 ? 9.123   -18.379 -5.076  1.00 34.15  ? 196 LYS C C   1 
ATOM   8743  O O   . LYS C 1 196 ? 8.909   -19.009 -4.068  1.00 41.47  ? 196 LYS C O   1 
ATOM   8744  C CB  . LYS C 1 196 ? 11.312  -17.676 -4.020  1.00 37.74  ? 196 LYS C CB  1 
ATOM   8745  C CG  . LYS C 1 196 ? 12.719  -17.120 -4.186  1.00 43.40  ? 196 LYS C CG  1 
ATOM   8746  C CD  . LYS C 1 196 ? 13.646  -18.087 -4.939  1.00 43.63  ? 196 LYS C CD  1 
ATOM   8747  C CE  . LYS C 1 196 ? 14.965  -17.444 -5.306  1.00 54.01  ? 196 LYS C CE  1 
ATOM   8748  N NZ  . LYS C 1 196 ? 15.812  -18.389 -6.063  1.00 59.85  ? 196 LYS C NZ  1 
ATOM   8749  N N   . GLY C 1 197 ? 8.160   -18.138 -5.961  1.00 34.69  ? 197 GLY C N   1 
ATOM   8750  C CA  . GLY C 1 197 ? 6.848   -18.752 -5.901  1.00 37.76  ? 197 GLY C CA  1 
ATOM   8751  C C   . GLY C 1 197 ? 5.975   -18.375 -4.697  1.00 36.75  ? 197 GLY C C   1 
ATOM   8752  O O   . GLY C 1 197 ? 5.041   -19.122 -4.366  1.00 37.21  ? 197 GLY C O   1 
ATOM   8753  N N   . ASP C 1 198 ? 6.235   -17.215 -4.065  1.00 38.01  ? 198 ASP C N   1 
ATOM   8754  C CA  . ASP C 1 198 ? 5.305   -16.648 -3.094  1.00 33.82  ? 198 ASP C CA  1 
ATOM   8755  C C   . ASP C 1 198 ? 5.143   -17.631 -1.934  1.00 35.62  ? 198 ASP C C   1 
ATOM   8756  O O   . ASP C 1 198 ? 4.037   -17.842 -1.426  1.00 37.61  ? 198 ASP C O   1 
ATOM   8757  C CB  . ASP C 1 198 ? 3.961   -16.325 -3.755  1.00 32.59  ? 198 ASP C CB  1 
ATOM   8758  C CG  . ASP C 1 198 ? 3.008   -15.413 -3.015  1.00 35.31  ? 198 ASP C CG  1 
ATOM   8759  O OD1 . ASP C 1 198 ? 3.438   -14.747 -2.074  1.00 34.54  ? 198 ASP C OD1 1 
ATOM   8760  O OD2 . ASP C 1 198 ? 1.816   -15.383 -3.398  1.00 40.96  ? 198 ASP C OD2 1 
ATOM   8761  N N   . THR C 1 199 ? 6.261   -18.207 -1.496  1.00 32.71  ? 199 THR C N   1 
ATOM   8762  C CA  . THR C 1 199 ? 6.288   -18.982 -0.257  1.00 39.01  ? 199 THR C CA  1 
ATOM   8763  C C   . THR C 1 199 ? 7.172   -18.279 0.766   1.00 34.73  ? 199 THR C C   1 
ATOM   8764  O O   . THR C 1 199 ? 8.222   -17.745 0.429   1.00 36.96  ? 199 THR C O   1 
ATOM   8765  C CB  . THR C 1 199 ? 6.802   -20.407 -0.480  1.00 41.29  ? 199 THR C CB  1 
ATOM   8766  O OG1 . THR C 1 199 ? 8.121   -20.234 -0.994  1.00 47.98  ? 199 THR C OG1 1 
ATOM   8767  C CG2 . THR C 1 199 ? 5.964   -21.194 -1.462  1.00 42.08  ? 199 THR C CG2 1 
ATOM   8768  N N   . HIS C 1 200 ? 6.783   -18.343 2.037   1.00 40.10  ? 200 HIS C N   1 
ATOM   8769  C CA  . HIS C 1 200 ? 7.271   -17.368 3.009   1.00 41.65  ? 200 HIS C CA  1 
ATOM   8770  C C   . HIS C 1 200 ? 7.944   -18.097 4.157   1.00 49.48  ? 200 HIS C C   1 
ATOM   8771  O O   . HIS C 1 200 ? 7.402   -19.067 4.669   1.00 42.97  ? 200 HIS C O   1 
ATOM   8772  C CB  . HIS C 1 200 ? 6.141   -16.420 3.405   1.00 37.56  ? 200 HIS C CB  1 
ATOM   8773  C CG  . HIS C 1 200 ? 5.770   -15.632 2.217   1.00 36.40  ? 200 HIS C CG  1 
ATOM   8774  N ND1 . HIS C 1 200 ? 6.571   -14.609 1.784   1.00 35.49  ? 200 HIS C ND1 1 
ATOM   8775  C CD2 . HIS C 1 200 ? 4.823   -15.782 1.294   1.00 39.84  ? 200 HIS C CD2 1 
ATOM   8776  C CE1 . HIS C 1 200 ? 6.045   -14.093 0.689   1.00 41.73  ? 200 HIS C CE1 1 
ATOM   8777  N NE2 . HIS C 1 200 ? 4.999   -14.806 0.346   1.00 35.49  ? 200 HIS C NE2 1 
ATOM   8778  N N   . ILE C 1 201 ? 9.159   -17.638 4.486   1.00 51.99  ? 201 ILE C N   1 
ATOM   8779  C CA  . ILE C 1 201 ? 9.975   -18.263 5.503   1.00 45.14  ? 201 ILE C CA  1 
ATOM   8780  C C   . ILE C 1 201 ? 10.016  -17.324 6.700   1.00 45.43  ? 201 ILE C C   1 
ATOM   8781  O O   . ILE C 1 201 ? 10.220  -16.127 6.523   1.00 44.18  ? 201 ILE C O   1 
ATOM   8782  C CB  . ILE C 1 201 ? 11.355  -18.593 4.918   1.00 41.81  ? 201 ILE C CB  1 
ATOM   8783  C CG1 . ILE C 1 201 ? 11.229  -19.638 3.809   1.00 41.73  ? 201 ILE C CG1 1 
ATOM   8784  C CG2 . ILE C 1 201 ? 12.298  -19.065 6.020   1.00 45.54  ? 201 ILE C CG2 1 
ATOM   8785  C CD1 . ILE C 1 201 ? 12.400  -19.665 2.843   1.00 42.86  ? 201 ILE C CD1 1 
ATOM   8786  N N   . ALA C 1 202 ? 9.726   -17.871 7.891   1.00 49.58  ? 202 ALA C N   1 
ATOM   8787  C CA  . ALA C 1 202 ? 9.700   -17.088 9.124   1.00 47.43  ? 202 ALA C CA  1 
ATOM   8788  C C   . ALA C 1 202 ? 11.123  -16.735 9.555   1.00 41.92  ? 202 ALA C C   1 
ATOM   8789  O O   . ALA C 1 202 ? 12.060  -17.451 9.230   1.00 32.09  ? 202 ALA C O   1 
ATOM   8790  C CB  . ALA C 1 202 ? 9.005   -17.861 10.236  1.00 42.12  ? 202 ALA C CB  1 
ATOM   8791  N N   . PRO C 1 203 ? 11.293  -15.645 10.335  1.00 42.91  ? 203 PRO C N   1 
ATOM   8792  C CA  . PRO C 1 203 ? 12.541  -15.344 11.008  1.00 44.70  ? 203 PRO C CA  1 
ATOM   8793  C C   . PRO C 1 203 ? 12.996  -16.513 11.870  1.00 43.64  ? 203 PRO C C   1 
ATOM   8794  O O   . PRO C 1 203 ? 12.177  -17.186 12.466  1.00 46.18  ? 203 PRO C O   1 
ATOM   8795  C CB  . PRO C 1 203 ? 12.229  -14.189 11.966  1.00 48.96  ? 203 PRO C CB  1 
ATOM   8796  C CG  . PRO C 1 203 ? 10.910  -13.613 11.508  1.00 48.83  ? 203 PRO C CG  1 
ATOM   8797  C CD  . PRO C 1 203 ? 10.240  -14.660 10.644  1.00 50.21  ? 203 PRO C CD  1 
ATOM   8798  N N   . ASP C 1 204 ? 14.305  -16.730 11.900  1.00 42.88  ? 204 ASP C N   1 
ATOM   8799  C CA  . ASP C 1 204 ? 14.934  -17.629 12.847  1.00 51.72  ? 204 ASP C CA  1 
ATOM   8800  C C   . ASP C 1 204 ? 15.327  -16.816 14.088  1.00 51.68  ? 204 ASP C C   1 
ATOM   8801  O O   . ASP C 1 204 ? 16.224  -15.990 14.020  1.00 41.86  ? 204 ASP C O   1 
ATOM   8802  C CB  . ASP C 1 204 ? 16.149  -18.305 12.205  1.00 49.58  ? 204 ASP C CB  1 
ATOM   8803  C CG  . ASP C 1 204 ? 16.691  -19.477 13.003  1.00 49.95  ? 204 ASP C CG  1 
ATOM   8804  O OD1 . ASP C 1 204 ? 16.810  -19.340 14.212  1.00 52.41  ? 204 ASP C OD1 1 
ATOM   8805  O OD2 . ASP C 1 204 ? 16.992  -20.522 12.387  1.00 61.81  ? 204 ASP C OD2 1 
ATOM   8806  N N   . PRO C 1 205 ? 14.704  -17.019 15.268  1.00 53.18  ? 205 PRO C N   1 
ATOM   8807  C CA  . PRO C 1 205 ? 15.099  -16.278 16.476  1.00 54.68  ? 205 PRO C CA  1 
ATOM   8808  C C   . PRO C 1 205 ? 16.525  -16.499 16.979  1.00 49.52  ? 205 PRO C C   1 
ATOM   8809  O O   . PRO C 1 205 ? 16.938  -15.808 17.893  1.00 53.24  ? 205 PRO C O   1 
ATOM   8810  C CB  . PRO C 1 205 ? 14.138  -16.804 17.558  1.00 57.54  ? 205 PRO C CB  1 
ATOM   8811  C CG  . PRO C 1 205 ? 13.692  -18.155 17.016  1.00 61.85  ? 205 PRO C CG  1 
ATOM   8812  C CD  . PRO C 1 205 ? 13.626  -17.988 15.509  1.00 51.71  ? 205 PRO C CD  1 
ATOM   8813  N N   . ASN C 1 206 ? 17.278  -17.426 16.367  1.00 50.25  ? 206 ASN C N   1 
ATOM   8814  C CA  . ASN C 1 206 ? 18.667  -17.699 16.732  1.00 57.61  ? 206 ASN C CA  1 
ATOM   8815  C C   . ASN C 1 206 ? 19.678  -17.033 15.791  1.00 58.21  ? 206 ASN C C   1 
ATOM   8816  O O   . ASN C 1 206 ? 20.880  -17.176 15.981  1.00 50.25  ? 206 ASN C O   1 
ATOM   8817  C CB  . ASN C 1 206 ? 18.978  -19.206 16.739  1.00 56.19  ? 206 ASN C CB  1 
ATOM   8818  C CG  . ASN C 1 206 ? 18.293  -19.942 17.872  1.00 63.61  ? 206 ASN C CG  1 
ATOM   8819  O OD1 . ASN C 1 206 ? 18.248  -19.446 19.001  1.00 62.89  ? 206 ASN C OD1 1 
ATOM   8820  N ND2 . ASN C 1 206 ? 17.742  -21.109 17.579  1.00 64.10  ? 206 ASN C ND2 1 
ATOM   8821  N N   . LEU C 1 207 ? 19.234  -16.358 14.727  1.00 55.82  ? 207 LEU C N   1 
ATOM   8822  C CA  . LEU C 1 207 ? 20.208  -15.785 13.811  1.00 48.14  ? 207 LEU C CA  1 
ATOM   8823  C C   . LEU C 1 207 ? 20.334  -14.296 14.113  1.00 41.92  ? 207 LEU C C   1 
ATOM   8824  O O   . LEU C 1 207 ? 19.483  -13.715 14.756  1.00 45.12  ? 207 LEU C O   1 
ATOM   8825  C CB  . LEU C 1 207 ? 19.786  -16.064 12.367  1.00 46.59  ? 207 LEU C CB  1 
ATOM   8826  C CG  . LEU C 1 207 ? 19.980  -17.496 11.843  1.00 46.30  ? 207 LEU C CG  1 
ATOM   8827  C CD1 . LEU C 1 207 ? 19.566  -17.588 10.394  1.00 48.07  ? 207 LEU C CD1 1 
ATOM   8828  C CD2 . LEU C 1 207 ? 21.421  -17.978 11.931  1.00 46.44  ? 207 LEU C CD2 1 
ATOM   8829  N N   . ASP C 1 208 ? 21.461  -13.715 13.717  1.00 43.42  ? 208 ASP C N   1 
ATOM   8830  C CA  . ASP C 1 208 ? 21.657  -12.276 13.689  1.00 39.05  ? 208 ASP C CA  1 
ATOM   8831  C C   . ASP C 1 208 ? 20.866  -11.627 12.534  1.00 36.27  ? 208 ASP C C   1 
ATOM   8832  O O   . ASP C 1 208 ? 20.242  -12.287 11.710  1.00 36.76  ? 208 ASP C O   1 
ATOM   8833  C CB  . ASP C 1 208 ? 23.162  -12.032 13.590  1.00 40.70  ? 208 ASP C CB  1 
ATOM   8834  C CG  . ASP C 1 208 ? 23.817  -12.724 12.410  1.00 43.89  ? 208 ASP C CG  1 
ATOM   8835  O OD1 . ASP C 1 208 ? 24.001  -13.962 12.474  1.00 44.28  ? 208 ASP C OD1 1 
ATOM   8836  O OD2 . ASP C 1 208 ? 24.123  -12.018 11.403  1.00 44.59  ? 208 ASP C OD2 1 
ATOM   8837  N N   . TRP C 1 209 ? 20.943  -10.303 12.438  1.00 32.30  ? 209 TRP C N   1 
ATOM   8838  C CA  . TRP C 1 209 ? 20.042  -9.543  11.608  1.00 33.10  ? 209 TRP C CA  1 
ATOM   8839  C C   . TRP C 1 209 ? 20.278  -9.821  10.116  1.00 34.83  ? 209 TRP C C   1 
ATOM   8840  O O   . TRP C 1 209 ? 19.339  -10.099 9.390   1.00 38.75  ? 209 TRP C O   1 
ATOM   8841  C CB  . TRP C 1 209 ? 20.284  -8.087  11.982  1.00 39.29  ? 209 TRP C CB  1 
ATOM   8842  C CG  . TRP C 1 209 ? 19.456  -7.048  11.289  1.00 37.46  ? 209 TRP C CG  1 
ATOM   8843  C CD1 . TRP C 1 209 ? 18.148  -6.757  11.515  1.00 42.04  ? 209 TRP C CD1 1 
ATOM   8844  C CD2 . TRP C 1 209 ? 19.916  -6.094  10.332  1.00 35.15  ? 209 TRP C CD2 1 
ATOM   8845  N NE1 . TRP C 1 209 ? 17.761  -5.704  10.734  1.00 43.00  ? 209 TRP C NE1 1 
ATOM   8846  C CE2 . TRP C 1 209 ? 18.831  -5.254  10.030  1.00 38.16  ? 209 TRP C CE2 1 
ATOM   8847  C CE3 . TRP C 1 209 ? 21.137  -5.872  9.689   1.00 37.24  ? 209 TRP C CE3 1 
ATOM   8848  C CZ2 . TRP C 1 209 ? 18.912  -4.220  9.101   1.00 40.89  ? 209 TRP C CZ2 1 
ATOM   8849  C CZ3 . TRP C 1 209 ? 21.221  -4.842  8.783   1.00 39.01  ? 209 TRP C CZ3 1 
ATOM   8850  C CH2 . TRP C 1 209 ? 20.126  -4.021  8.499   1.00 38.41  ? 209 TRP C CH2 1 
ATOM   8851  N N   . SER C 1 210 ? 21.539  -9.746  9.673   1.00 34.08  ? 210 SER C N   1 
ATOM   8852  C CA  . SER C 1 210 ? 21.978  -10.014 8.312   1.00 36.91  ? 210 SER C CA  1 
ATOM   8853  C C   . SER C 1 210 ? 21.692  -11.448 7.884   1.00 39.79  ? 210 SER C C   1 
ATOM   8854  O O   . SER C 1 210 ? 21.281  -11.710 6.757   1.00 38.14  ? 210 SER C O   1 
ATOM   8855  C CB  . SER C 1 210 ? 23.478  -9.789  8.198   1.00 39.46  ? 210 SER C CB  1 
ATOM   8856  O OG  . SER C 1 210 ? 23.818  -8.474  8.585   1.00 48.18  ? 210 SER C OG  1 
ATOM   8857  N N   . ALA C 1 211 ? 22.075  -12.385 8.750   1.00 38.57  ? 211 ALA C N   1 
ATOM   8858  C CA  . ALA C 1 211 ? 21.858  -13.789 8.470   1.00 39.71  ? 211 ALA C CA  1 
ATOM   8859  C C   . ALA C 1 211 ? 20.374  -14.069 8.286   1.00 36.19  ? 211 ALA C C   1 
ATOM   8860  O O   . ALA C 1 211 ? 20.049  -14.925 7.471   1.00 38.38  ? 211 ALA C O   1 
ATOM   8861  C CB  . ALA C 1 211 ? 22.450  -14.628 9.581   1.00 41.65  ? 211 ALA C CB  1 
ATOM   8862  N N   . ASN C 1 212 ? 19.516  -13.410 9.092   1.00 34.24  ? 212 ASN C N   1 
ATOM   8863  C CA  . ASN C 1 212 ? 18.078  -13.634 8.993   1.00 39.29  ? 212 ASN C CA  1 
ATOM   8864  C C   . ASN C 1 212 ? 17.527  -13.218 7.634   1.00 32.26  ? 212 ASN C C   1 
ATOM   8865  O O   . ASN C 1 212 ? 16.699  -13.909 7.086   1.00 34.92  ? 212 ASN C O   1 
ATOM   8866  C CB  . ASN C 1 212 ? 17.239  -12.923 10.059  1.00 35.96  ? 212 ASN C CB  1 
ATOM   8867  C CG  . ASN C 1 212 ? 16.662  -13.921 11.046  1.00 41.76  ? 212 ASN C CG  1 
ATOM   8868  O OD1 . ASN C 1 212 ? 16.168  -14.979 10.662  1.00 47.41  ? 212 ASN C OD1 1 
ATOM   8869  N ND2 . ASN C 1 212 ? 16.747  -13.629 12.331  1.00 38.82  ? 212 ASN C ND2 1 
ATOM   8870  N N   . LEU C 1 213 ? 17.967  -12.085 7.095   1.00 35.76  ? 213 LEU C N   1 
ATOM   8871  C CA  . LEU C 1 213 ? 17.540  -11.701 5.755   1.00 37.71  ? 213 LEU C CA  1 
ATOM   8872  C C   . LEU C 1 213 ? 17.834  -12.813 4.731   1.00 37.16  ? 213 LEU C C   1 
ATOM   8873  O O   . LEU C 1 213 ? 17.023  -13.099 3.841   1.00 37.79  ? 213 LEU C O   1 
ATOM   8874  C CB  . LEU C 1 213 ? 18.240  -10.405 5.360   1.00 33.78  ? 213 LEU C CB  1 
ATOM   8875  C CG  . LEU C 1 213 ? 17.977  -9.931  3.932   1.00 33.82  ? 213 LEU C CG  1 
ATOM   8876  C CD1 . LEU C 1 213 ? 16.495  -9.835  3.627   1.00 34.62  ? 213 LEU C CD1 1 
ATOM   8877  C CD2 . LEU C 1 213 ? 18.633  -8.602  3.750   1.00 35.28  ? 213 LEU C CD2 1 
ATOM   8878  N N   . ALA C 1 214 ? 18.991  -13.457 4.867   1.00 36.46  ? 214 ALA C N   1 
ATOM   8879  C CA  . ALA C 1 214 ? 19.412  -14.491 3.929   1.00 40.71  ? 214 ALA C CA  1 
ATOM   8880  C C   . ALA C 1 214 ? 18.532  -15.715 4.126   1.00 40.94  ? 214 ALA C C   1 
ATOM   8881  O O   . ALA C 1 214 ? 18.002  -16.260 3.160   1.00 38.88  ? 214 ALA C O   1 
ATOM   8882  C CB  . ALA C 1 214 ? 20.869  -14.811 4.122   1.00 35.81  ? 214 ALA C CB  1 
ATOM   8883  N N   . HIS C 1 215 ? 18.347  -16.093 5.403   1.00 36.55  ? 215 HIS C N   1 
ATOM   8884  C CA  . HIS C 1 215 ? 17.502  -17.211 5.764   1.00 34.82  ? 215 HIS C CA  1 
ATOM   8885  C C   . HIS C 1 215 ? 16.104  -17.043 5.164   1.00 37.21  ? 215 HIS C C   1 
ATOM   8886  O O   . HIS C 1 215 ? 15.524  -17.970 4.597   1.00 33.29  ? 215 HIS C O   1 
ATOM   8887  C CB  . HIS C 1 215 ? 17.321  -17.208 7.285   1.00 35.66  ? 215 HIS C CB  1 
ATOM   8888  C CG  . HIS C 1 215 ? 16.441  -18.273 7.801   1.00 37.65  ? 215 HIS C CG  1 
ATOM   8889  N ND1 . HIS C 1 215 ? 16.639  -19.596 7.484   1.00 45.30  ? 215 HIS C ND1 1 
ATOM   8890  C CD2 . HIS C 1 215 ? 15.384  -18.233 8.610   1.00 41.08  ? 215 HIS C CD2 1 
ATOM   8891  C CE1 . HIS C 1 215 ? 15.727  -20.332 8.110   1.00 45.87  ? 215 HIS C CE1 1 
ATOM   8892  N NE2 . HIS C 1 215 ? 14.952  -19.531 8.794   1.00 43.59  ? 215 HIS C NE2 1 
ATOM   8893  N N   . MET C 1 216 ? 15.550  -15.842 5.342   1.00 36.29  ? 216 MET C N   1 
ATOM   8894  C CA  . MET C 1 216 ? 14.169  -15.576 4.979   1.00 34.37  ? 216 MET C CA  1 
ATOM   8895  C C   . MET C 1 216 ? 14.045  -15.447 3.463   1.00 34.95  ? 216 MET C C   1 
ATOM   8896  O O   . MET C 1 216 ? 12.944  -15.522 2.955   1.00 38.08  ? 216 MET C O   1 
ATOM   8897  C CB  . MET C 1 216 ? 13.704  -14.289 5.666   1.00 35.52  ? 216 MET C CB  1 
ATOM   8898  C CG  . MET C 1 216 ? 13.321  -14.504 7.128   1.00 34.59  ? 216 MET C CG  1 
ATOM   8899  S SD  . MET C 1 216 ? 12.490  -13.092 7.872   1.00 35.69  ? 216 MET C SD  1 
ATOM   8900  C CE  . MET C 1 216 ? 13.670  -11.768 7.656   1.00 37.01  ? 216 MET C CE  1 
ATOM   8901  N N   . MET C 1 217 ? 15.172  -15.249 2.760   1.00 39.77  ? 217 MET C N   1 
ATOM   8902  C CA  . MET C 1 217 ? 15.210  -15.180 1.304   1.00 35.93  ? 217 MET C CA  1 
ATOM   8903  C C   . MET C 1 217 ? 15.357  -16.586 0.729   1.00 37.38  ? 217 MET C C   1 
ATOM   8904  O O   . MET C 1 217 ? 15.038  -16.830 -0.444  1.00 37.58  ? 217 MET C O   1 
ATOM   8905  C CB  . MET C 1 217 ? 16.362  -14.290 0.802   1.00 34.97  ? 217 MET C CB  1 
ATOM   8906  C CG  . MET C 1 217 ? 16.037  -12.789 0.825   1.00 35.31  ? 217 MET C CG  1 
ATOM   8907  S SD  . MET C 1 217 ? 17.515  -11.794 0.496   1.00 38.25  ? 217 MET C SD  1 
ATOM   8908  C CE  . MET C 1 217 ? 17.801  -12.135 -1.241  1.00 38.17  ? 217 MET C CE  1 
ATOM   8909  N N   . GLY C 1 218 ? 15.780  -17.541 1.557   1.00 37.67  ? 218 GLY C N   1 
ATOM   8910  C CA  . GLY C 1 218 ? 15.948  -18.901 1.054   1.00 35.14  ? 218 GLY C CA  1 
ATOM   8911  C C   . GLY C 1 218 ? 17.388  -19.435 1.084   1.00 39.54  ? 218 GLY C C   1 
ATOM   8912  O O   . GLY C 1 218 ? 17.628  -20.520 0.585   1.00 39.25  ? 218 GLY C O   1 
ATOM   8913  N N   . PHE C 1 219 ? 18.340  -18.712 1.693   1.00 42.63  ? 219 PHE C N   1 
ATOM   8914  C CA  . PHE C 1 219 ? 19.762  -19.040 1.610   1.00 39.84  ? 219 PHE C CA  1 
ATOM   8915  C C   . PHE C 1 219 ? 20.354  -19.298 2.988   1.00 37.52  ? 219 PHE C C   1 
ATOM   8916  O O   . PHE C 1 219 ? 20.411  -18.394 3.793   1.00 42.58  ? 219 PHE C O   1 
ATOM   8917  C CB  . PHE C 1 219 ? 20.507  -17.857 0.985   1.00 41.22  ? 219 PHE C CB  1 
ATOM   8918  C CG  . PHE C 1 219 ? 20.170  -17.613 -0.467  1.00 43.32  ? 219 PHE C CG  1 
ATOM   8919  C CD1 . PHE C 1 219 ? 20.723  -18.392 -1.472  1.00 39.54  ? 219 PHE C CD1 1 
ATOM   8920  C CD2 . PHE C 1 219 ? 19.242  -16.648 -0.823  1.00 47.38  ? 219 PHE C CD2 1 
ATOM   8921  C CE1 . PHE C 1 219 ? 20.386  -18.188 -2.802  1.00 42.24  ? 219 PHE C CE1 1 
ATOM   8922  C CE2 . PHE C 1 219 ? 18.914  -16.430 -2.154  1.00 50.05  ? 219 PHE C CE2 1 
ATOM   8923  C CZ  . PHE C 1 219 ? 19.476  -17.212 -3.148  1.00 50.57  ? 219 PHE C CZ  1 
ATOM   8924  N N   . ASP C 1 220 ? 20.859  -20.499 3.260   1.00 45.69  ? 220 ASP C N   1 
ATOM   8925  C CA  . ASP C 1 220 ? 21.294  -20.822 4.610   1.00 49.34  ? 220 ASP C CA  1 
ATOM   8926  C C   . ASP C 1 220 ? 22.772  -21.216 4.687   1.00 47.63  ? 220 ASP C C   1 
ATOM   8927  O O   . ASP C 1 220 ? 23.267  -21.517 5.766   1.00 50.24  ? 220 ASP C O   1 
ATOM   8928  C CB  . ASP C 1 220 ? 20.374  -21.869 5.237   1.00 48.56  ? 220 ASP C CB  1 
ATOM   8929  C CG  . ASP C 1 220 ? 18.999  -21.299 5.568   1.00 58.59  ? 220 ASP C CG  1 
ATOM   8930  O OD1 . ASP C 1 220 ? 18.900  -20.442 6.481   1.00 56.34  ? 220 ASP C OD1 1 
ATOM   8931  O OD2 . ASP C 1 220 ? 18.027  -21.704 4.913   1.00 53.86  ? 220 ASP C OD2 1 
ATOM   8932  N N   . ASP C 1 221 ? 23.531  -21.151 3.597   1.00 49.20  ? 221 ASP C N   1 
ATOM   8933  C CA  . ASP C 1 221 ? 24.932  -21.540 3.710   1.00 51.15  ? 221 ASP C CA  1 
ATOM   8934  C C   . ASP C 1 221 ? 25.674  -20.477 4.519   1.00 47.40  ? 221 ASP C C   1 
ATOM   8935  O O   . ASP C 1 221 ? 25.414  -19.266 4.404   1.00 45.50  ? 221 ASP C O   1 
ATOM   8936  C CB  . ASP C 1 221 ? 25.575  -21.852 2.348   1.00 65.28  ? 221 ASP C CB  1 
ATOM   8937  C CG  . ASP C 1 221 ? 25.209  -23.224 1.768   1.00 80.38  ? 221 ASP C CG  1 
ATOM   8938  O OD1 . ASP C 1 221 ? 24.151  -23.808 2.160   1.00 73.40  ? 221 ASP C OD1 1 
ATOM   8939  O OD2 . ASP C 1 221 ? 25.999  -23.735 0.949   1.00 83.96  ? 221 ASP C OD2 1 
ATOM   8940  N N   . PHE C 1 222 ? 26.637  -20.952 5.310   1.00 46.45  ? 222 PHE C N   1 
ATOM   8941  C CA  . PHE C 1 222 ? 27.439  -20.105 6.173   1.00 46.18  ? 222 PHE C CA  1 
ATOM   8942  C C   . PHE C 1 222 ? 28.087  -18.983 5.365   1.00 42.96  ? 222 PHE C C   1 
ATOM   8943  O O   . PHE C 1 222 ? 28.097  -17.825 5.788   1.00 41.07  ? 222 PHE C O   1 
ATOM   8944  C CB  . PHE C 1 222 ? 28.462  -20.973 6.909   1.00 51.96  ? 222 PHE C CB  1 
ATOM   8945  C CG  . PHE C 1 222 ? 29.492  -20.220 7.711   1.00 54.43  ? 222 PHE C CG  1 
ATOM   8946  C CD1 . PHE C 1 222 ? 29.159  -19.640 8.928   1.00 64.70  ? 222 PHE C CD1 1 
ATOM   8947  C CD2 . PHE C 1 222 ? 30.800  -20.098 7.239   1.00 59.33  ? 222 PHE C CD2 1 
ATOM   8948  C CE1 . PHE C 1 222 ? 30.119  -18.960 9.671   1.00 65.81  ? 222 PHE C CE1 1 
ATOM   8949  C CE2 . PHE C 1 222 ? 31.753  -19.407 7.973   1.00 62.38  ? 222 PHE C CE2 1 
ATOM   8950  C CZ  . PHE C 1 222 ? 31.405  -18.838 9.187   1.00 68.05  ? 222 PHE C CZ  1 
ATOM   8951  N N   . GLU C 1 223 ? 28.628  -19.321 4.197   1.00 43.79  ? 223 GLU C N   1 
ATOM   8952  C CA  . GLU C 1 223 ? 29.347  -18.350 3.395   1.00 46.52  ? 223 GLU C CA  1 
ATOM   8953  C C   . GLU C 1 223 ? 28.389  -17.244 2.973   1.00 42.13  ? 223 GLU C C   1 
ATOM   8954  O O   . GLU C 1 223 ? 28.832  -16.109 2.809   1.00 42.85  ? 223 GLU C O   1 
ATOM   8955  C CB  . GLU C 1 223 ? 29.988  -18.971 2.148   1.00 59.11  ? 223 GLU C CB  1 
ATOM   8956  C CG  . GLU C 1 223 ? 31.154  -19.908 2.429   1.00 69.74  ? 223 GLU C CG  1 
ATOM   8957  C CD  . GLU C 1 223 ? 31.789  -20.510 1.179   1.00 77.67  ? 223 GLU C CD  1 
ATOM   8958  O OE1 . GLU C 1 223 ? 32.318  -21.643 1.266   1.00 91.00  ? 223 GLU C OE1 1 
ATOM   8959  O OE2 . GLU C 1 223 ? 31.772  -19.843 0.117   1.00 69.36  ? 223 GLU C OE2 1 
ATOM   8960  N N   . VAL C 1 224 ? 27.102  -17.569 2.751   1.00 39.96  ? 224 VAL C N   1 
ATOM   8961  C CA  . VAL C 1 224 ? 26.133  -16.545 2.353   1.00 40.40  ? 224 VAL C CA  1 
ATOM   8962  C C   . VAL C 1 224 ? 25.830  -15.627 3.536   1.00 36.91  ? 224 VAL C C   1 
ATOM   8963  O O   . VAL C 1 224 ? 25.733  -14.405 3.380   1.00 42.62  ? 224 VAL C O   1 
ATOM   8964  C CB  . VAL C 1 224 ? 24.845  -17.148 1.765   1.00 42.78  ? 224 VAL C CB  1 
ATOM   8965  C CG1 . VAL C 1 224 ? 23.762  -16.110 1.547   1.00 47.72  ? 224 VAL C CG1 1 
ATOM   8966  C CG2 . VAL C 1 224 ? 25.133  -17.865 0.474   1.00 44.74  ? 224 VAL C CG2 1 
ATOM   8967  N N   . TYR C 1 225 ? 25.723  -16.200 4.730   1.00 38.14  ? 225 TYR C N   1 
ATOM   8968  C CA  . TYR C 1 225 ? 25.495  -15.391 5.928   1.00 40.85  ? 225 TYR C CA  1 
ATOM   8969  C C   . TYR C 1 225 ? 26.591  -14.338 6.079   1.00 35.10  ? 225 TYR C C   1 
ATOM   8970  O O   . TYR C 1 225 ? 26.322  -13.141 6.279   1.00 34.31  ? 225 TYR C O   1 
ATOM   8971  C CB  . TYR C 1 225 ? 25.423  -16.285 7.156   1.00 40.19  ? 225 TYR C CB  1 
ATOM   8972  C CG  . TYR C 1 225 ? 24.194  -17.150 7.303   1.00 42.91  ? 225 TYR C CG  1 
ATOM   8973  C CD1 . TYR C 1 225 ? 23.111  -17.063 6.445   1.00 42.48  ? 225 TYR C CD1 1 
ATOM   8974  C CD2 . TYR C 1 225 ? 24.103  -18.043 8.361   1.00 39.78  ? 225 TYR C CD2 1 
ATOM   8975  C CE1 . TYR C 1 225 ? 21.978  -17.844 6.624   1.00 42.28  ? 225 TYR C CE1 1 
ATOM   8976  C CE2 . TYR C 1 225 ? 22.982  -18.833 8.549   1.00 37.22  ? 225 TYR C CE2 1 
ATOM   8977  C CZ  . TYR C 1 225 ? 21.914  -18.722 7.687   1.00 38.95  ? 225 TYR C CZ  1 
ATOM   8978  O OH  . TYR C 1 225 ? 20.815  -19.500 7.882   1.00 42.09  ? 225 TYR C OH  1 
ATOM   8979  N N   . GLU C 1 226 ? 27.822  -14.811 5.886   1.00 37.12  ? 226 GLU C N   1 
ATOM   8980  C CA  . GLU C 1 226 ? 29.035  -14.011 5.948   1.00 35.06  ? 226 GLU C CA  1 
ATOM   8981  C C   . GLU C 1 226 ? 29.044  -12.936 4.867   1.00 34.01  ? 226 GLU C C   1 
ATOM   8982  O O   . GLU C 1 226 ? 29.377  -11.784 5.143   1.00 34.13  ? 226 GLU C O   1 
ATOM   8983  C CB  . GLU C 1 226 ? 30.230  -14.958 5.826   1.00 37.07  ? 226 GLU C CB  1 
ATOM   8984  C CG  . GLU C 1 226 ? 30.420  -15.832 7.058   1.00 40.36  ? 226 GLU C CG  1 
ATOM   8985  C CD  . GLU C 1 226 ? 30.967  -15.030 8.226   1.00 41.24  ? 226 GLU C CD  1 
ATOM   8986  O OE1 . GLU C 1 226 ? 30.175  -14.634 9.091   1.00 42.59  ? 226 GLU C OE1 1 
ATOM   8987  O OE2 . GLU C 1 226 ? 32.182  -14.804 8.264   1.00 46.77  ? 226 GLU C OE2 1 
ATOM   8988  N N   . LEU C 1 227 ? 28.654  -13.286 3.640   1.00 32.77  ? 227 LEU C N   1 
ATOM   8989  C CA  . LEU C 1 227 ? 28.592  -12.274 2.589   1.00 35.96  ? 227 LEU C CA  1 
ATOM   8990  C C   . LEU C 1 227 ? 27.650  -11.147 2.979   1.00 39.62  ? 227 LEU C C   1 
ATOM   8991  O O   . LEU C 1 227 ? 27.932  -9.983  2.724   1.00 37.41  ? 227 LEU C O   1 
ATOM   8992  C CB  . LEU C 1 227 ? 28.121  -12.905 1.291   1.00 34.24  ? 227 LEU C CB  1 
ATOM   8993  C CG  . LEU C 1 227 ? 27.698  -11.908 0.225   1.00 37.10  ? 227 LEU C CG  1 
ATOM   8994  C CD1 . LEU C 1 227 ? 28.868  -11.048 -0.215  1.00 40.91  ? 227 LEU C CD1 1 
ATOM   8995  C CD2 . LEU C 1 227 ? 27.102  -12.661 -0.959  1.00 40.14  ? 227 LEU C CD2 1 
ATOM   8996  N N   . PHE C 1 228 ? 26.532  -11.524 3.607   1.00 37.73  ? 228 PHE C N   1 
ATOM   8997  C CA  . PHE C 1 228 ? 25.483  -10.588 3.958   1.00 35.41  ? 228 PHE C CA  1 
ATOM   8998  C C   . PHE C 1 228 ? 25.942  -9.705  5.115   1.00 37.76  ? 228 PHE C C   1 
ATOM   8999  O O   . PHE C 1 228 ? 25.786  -8.484  5.065   1.00 38.41  ? 228 PHE C O   1 
ATOM   9000  C CB  . PHE C 1 228 ? 24.191  -11.357 4.266   1.00 37.82  ? 228 PHE C CB  1 
ATOM   9001  C CG  . PHE C 1 228 ? 23.278  -11.607 3.089   1.00 36.32  ? 228 PHE C CG  1 
ATOM   9002  C CD1 . PHE C 1 228 ? 23.771  -12.109 1.895   1.00 38.92  ? 228 PHE C CD1 1 
ATOM   9003  C CD2 . PHE C 1 228 ? 21.920  -11.318 3.173   1.00 36.00  ? 228 PHE C CD2 1 
ATOM   9004  C CE1 . PHE C 1 228 ? 22.925  -12.340 0.814   1.00 41.33  ? 228 PHE C CE1 1 
ATOM   9005  C CE2 . PHE C 1 228 ? 21.074  -11.557 2.098   1.00 38.11  ? 228 PHE C CE2 1 
ATOM   9006  C CZ  . PHE C 1 228 ? 21.578  -12.049 0.915   1.00 39.45  ? 228 PHE C CZ  1 
ATOM   9007  N N   . ARG C 1 229 ? 26.559  -10.300 6.140   1.00 36.13  ? 229 ARG C N   1 
ATOM   9008  C CA  . ARG C 1 229 ? 27.115  -9.486  7.214   1.00 34.50  ? 229 ARG C CA  1 
ATOM   9009  C C   . ARG C 1 229 ? 28.059  -8.458  6.597   1.00 36.94  ? 229 ARG C C   1 
ATOM   9010  O O   . ARG C 1 229 ? 27.996  -7.267  6.910   1.00 37.53  ? 229 ARG C O   1 
ATOM   9011  C CB  . ARG C 1 229 ? 27.784  -10.404 8.244   1.00 35.27  ? 229 ARG C CB  1 
ATOM   9012  C CG  . ARG C 1 229 ? 26.829  -11.332 8.984   1.00 34.95  ? 229 ARG C CG  1 
ATOM   9013  C CD  . ARG C 1 229 ? 27.453  -12.620 9.500   1.00 38.94  ? 229 ARG C CD  1 
ATOM   9014  N NE  . ARG C 1 229 ? 26.482  -13.442 10.193  1.00 40.23  ? 229 ARG C NE  1 
ATOM   9015  C CZ  . ARG C 1 229 ? 26.547  -14.763 10.353  1.00 37.64  ? 229 ARG C CZ  1 
ATOM   9016  N NH1 . ARG C 1 229 ? 27.589  -15.437 9.949   1.00 39.16  ? 229 ARG C NH1 1 
ATOM   9017  N NH2 . ARG C 1 229 ? 25.583  -15.414 10.969  1.00 41.49  ? 229 ARG C NH2 1 
ATOM   9018  N N   . LEU C 1 230 ? 28.915  -8.902  5.652   1.00 36.98  ? 230 LEU C N   1 
ATOM   9019  C CA  . LEU C 1 230 ? 29.909  -7.995  5.095   1.00 32.92  ? 230 LEU C CA  1 
ATOM   9020  C C   . LEU C 1 230 ? 29.230  -6.940  4.236   1.00 34.36  ? 230 LEU C C   1 
ATOM   9021  O O   . LEU C 1 230 ? 29.480  -5.732  4.404   1.00 37.66  ? 230 LEU C O   1 
ATOM   9022  C CB  . LEU C 1 230 ? 30.963  -8.766  4.297   1.00 38.54  ? 230 LEU C CB  1 
ATOM   9023  C CG  . LEU C 1 230 ? 31.995  -7.869  3.603   1.00 39.41  ? 230 LEU C CG  1 
ATOM   9024  C CD1 . LEU C 1 230 ? 32.830  -7.149  4.648   1.00 42.46  ? 230 LEU C CD1 1 
ATOM   9025  C CD2 . LEU C 1 230 ? 32.868  -8.656  2.659   1.00 39.63  ? 230 LEU C CD2 1 
ATOM   9026  N N   . TYR C 1 231 ? 28.288  -7.399  3.402   1.00 36.65  ? 231 TYR C N   1 
ATOM   9027  C CA  . TYR C 1 231 ? 27.489  -6.523  2.551   1.00 36.50  ? 231 TYR C CA  1 
ATOM   9028  C C   . TYR C 1 231 ? 26.831  -5.435  3.394   1.00 33.51  ? 231 TYR C C   1 
ATOM   9029  O O   . TYR C 1 231 ? 27.001  -4.241  3.121   1.00 35.47  ? 231 TYR C O   1 
ATOM   9030  C CB  . TYR C 1 231 ? 26.522  -7.337  1.670   1.00 45.70  ? 231 TYR C CB  1 
ATOM   9031  C CG  . TYR C 1 231 ? 25.790  -6.500  0.651   1.00 43.68  ? 231 TYR C CG  1 
ATOM   9032  C CD1 . TYR C 1 231 ? 24.786  -5.636  1.060   1.00 47.55  ? 231 TYR C CD1 1 
ATOM   9033  C CD2 . TYR C 1 231 ? 26.153  -6.474  -0.679  1.00 49.66  ? 231 TYR C CD2 1 
ATOM   9034  C CE1 . TYR C 1 231 ? 24.141  -4.796  0.174   1.00 47.86  ? 231 TYR C CE1 1 
ATOM   9035  C CE2 . TYR C 1 231 ? 25.488  -5.659  -1.592  1.00 51.34  ? 231 TYR C CE2 1 
ATOM   9036  C CZ  . TYR C 1 231 ? 24.477  -4.824  -1.158  1.00 44.39  ? 231 TYR C CZ  1 
ATOM   9037  O OH  . TYR C 1 231 ? 23.821  -3.948  -1.961  1.00 53.92  ? 231 TYR C OH  1 
ATOM   9038  N N   . MET C 1 232 ? 26.141  -5.837  4.458   1.00 38.16  ? 232 MET C N   1 
ATOM   9039  C CA  . MET C 1 232 ? 25.395  -4.900  5.297   1.00 39.70  ? 232 MET C CA  1 
ATOM   9040  C C   . MET C 1 232 ? 26.325  -3.893  5.990   1.00 37.25  ? 232 MET C C   1 
ATOM   9041  O O   . MET C 1 232 ? 26.008  -2.695  6.105   1.00 33.09  ? 232 MET C O   1 
ATOM   9042  C CB  . MET C 1 232 ? 24.585  -5.674  6.352   1.00 41.34  ? 232 MET C CB  1 
ATOM   9043  C CG  . MET C 1 232 ? 23.407  -6.456  5.787   1.00 45.64  ? 232 MET C CG  1 
ATOM   9044  S SD  . MET C 1 232 ? 22.321  -5.525  4.703   1.00 51.09  ? 232 MET C SD  1 
ATOM   9045  C CE  . MET C 1 232 ? 21.390  -6.884  4.005   1.00 54.73  ? 232 MET C CE  1 
ATOM   9046  N N   . PHE C 1 233 ? 27.477  -4.392  6.470   1.00 39.10  ? 233 PHE C N   1 
ATOM   9047  C CA  . PHE C 1 233 ? 28.535  -3.552  7.041   1.00 35.51  ? 233 PHE C CA  1 
ATOM   9048  C C   . PHE C 1 233 ? 29.021  -2.513  6.031   1.00 32.40  ? 233 PHE C C   1 
ATOM   9049  O O   . PHE C 1 233 ? 29.107  -1.320  6.321   1.00 35.85  ? 233 PHE C O   1 
ATOM   9050  C CB  . PHE C 1 233 ? 29.671  -4.465  7.526   1.00 34.81  ? 233 PHE C CB  1 
ATOM   9051  C CG  . PHE C 1 233 ? 30.950  -3.796  7.930   1.00 37.59  ? 233 PHE C CG  1 
ATOM   9052  C CD1 . PHE C 1 233 ? 31.087  -3.214  9.186   1.00 40.91  ? 233 PHE C CD1 1 
ATOM   9053  C CD2 . PHE C 1 233 ? 32.022  -3.727  7.039   1.00 41.91  ? 233 PHE C CD2 1 
ATOM   9054  C CE1 . PHE C 1 233 ? 32.280  -2.603  9.545   1.00 37.26  ? 233 PHE C CE1 1 
ATOM   9055  C CE2 . PHE C 1 233 ? 33.218  -3.111  7.394   1.00 39.63  ? 233 PHE C CE2 1 
ATOM   9056  C CZ  . PHE C 1 233 ? 33.346  -2.562  8.653   1.00 40.40  ? 233 PHE C CZ  1 
ATOM   9057  N N   . LEU C 1 234 ? 29.349  -2.959  4.825   1.00 35.95  ? 234 LEU C N   1 
ATOM   9058  C CA  . LEU C 1 234 ? 30.075  -2.096  3.897   1.00 38.13  ? 234 LEU C CA  1 
ATOM   9059  C C   . LEU C 1 234 ? 29.182  -0.991  3.361   1.00 36.70  ? 234 LEU C C   1 
ATOM   9060  O O   . LEU C 1 234 ? 29.674  0.102   3.102   1.00 40.32  ? 234 LEU C O   1 
ATOM   9061  C CB  . LEU C 1 234 ? 30.645  -2.899  2.725   1.00 40.58  ? 234 LEU C CB  1 
ATOM   9062  C CG  . LEU C 1 234 ? 31.850  -3.806  2.998   1.00 39.90  ? 234 LEU C CG  1 
ATOM   9063  C CD1 . LEU C 1 234 ? 32.325  -4.426  1.698   1.00 41.32  ? 234 LEU C CD1 1 
ATOM   9064  C CD2 . LEU C 1 234 ? 32.986  -3.062  3.681   1.00 37.64  ? 234 LEU C CD2 1 
ATOM   9065  N N   . HIS C 1 235 ? 27.881  -1.258  3.210   1.00 42.06  ? 235 HIS C N   1 
ATOM   9066  C CA  . HIS C 1 235 ? 27.005  -0.288  2.564   1.00 34.30  ? 235 HIS C CA  1 
ATOM   9067  C C   . HIS C 1 235 ? 26.260  0.585   3.567   1.00 33.38  ? 235 HIS C C   1 
ATOM   9068  O O   . HIS C 1 235 ? 25.413  1.372   3.142   1.00 37.42  ? 235 HIS C O   1 
ATOM   9069  C CB  . HIS C 1 235 ? 26.042  -0.986  1.608   1.00 35.20  ? 235 HIS C CB  1 
ATOM   9070  C CG  . HIS C 1 235 ? 26.632  -1.621  0.379   1.00 40.97  ? 235 HIS C CG  1 
ATOM   9071  N ND1 . HIS C 1 235 ? 27.178  -2.899  0.361   1.00 38.01  ? 235 HIS C ND1 1 
ATOM   9072  C CD2 . HIS C 1 235 ? 26.671  -1.171  -0.919  1.00 39.93  ? 235 HIS C CD2 1 
ATOM   9073  C CE1 . HIS C 1 235 ? 27.559  -3.190  -0.891  1.00 39.99  ? 235 HIS C CE1 1 
ATOM   9074  N NE2 . HIS C 1 235 ? 27.270  -2.156  -1.683  1.00 38.55  ? 235 HIS C NE2 1 
ATOM   9075  N N   . SER C 1 236 ? 26.565  0.472   4.877   1.00 38.21  ? 236 SER C N   1 
ATOM   9076  C CA  . SER C 1 236 ? 25.786  1.108   5.948   1.00 38.92  ? 236 SER C CA  1 
ATOM   9077  C C   . SER C 1 236 ? 25.735  2.629   5.828   1.00 37.22  ? 236 SER C C   1 
ATOM   9078  O O   . SER C 1 236 ? 24.710  3.258   6.058   1.00 33.55  ? 236 SER C O   1 
ATOM   9079  C CB  . SER C 1 236 ? 26.333  0.763   7.302   1.00 42.06  ? 236 SER C CB  1 
ATOM   9080  O OG  . SER C 1 236 ? 27.701  1.056   7.348   1.00 40.77  ? 236 SER C OG  1 
ATOM   9081  N N   . ASP C 1 237 ? 26.841  3.257   5.471   1.00 38.06  ? 237 ASP C N   1 
ATOM   9082  C CA  . ASP C 1 237 ? 26.887  4.705   5.577   1.00 36.49  ? 237 ASP C CA  1 
ATOM   9083  C C   . ASP C 1 237 ? 27.995  5.194   4.677   1.00 37.70  ? 237 ASP C C   1 
ATOM   9084  O O   . ASP C 1 237 ? 28.998  4.492   4.502   1.00 39.58  ? 237 ASP C O   1 
ATOM   9085  C CB  . ASP C 1 237 ? 27.179  5.107   7.019   1.00 42.87  ? 237 ASP C CB  1 
ATOM   9086  C CG  . ASP C 1 237 ? 26.767  6.514   7.422   1.00 55.63  ? 237 ASP C CG  1 
ATOM   9087  O OD1 . ASP C 1 237 ? 25.638  6.945   7.012   1.00 52.92  ? 237 ASP C OD1 1 
ATOM   9088  O OD2 . ASP C 1 237 ? 27.535  7.138   8.239   1.00 51.51  ? 237 ASP C OD2 1 
ATOM   9089  N N   . HIS C 1 238 ? 27.810  6.398   4.144   1.00 34.55  ? 238 HIS C N   1 
ATOM   9090  C CA  . HIS C 1 238 ? 28.832  7.011   3.306   1.00 37.85  ? 238 HIS C CA  1 
ATOM   9091  C C   . HIS C 1 238 ? 28.660  8.521   3.311   1.00 37.21  ? 238 HIS C C   1 
ATOM   9092  O O   . HIS C 1 238 ? 28.341  9.106   2.278   1.00 37.28  ? 238 HIS C O   1 
ATOM   9093  C CB  . HIS C 1 238 ? 28.787  6.430   1.889   1.00 40.61  ? 238 HIS C CB  1 
ATOM   9094  C CG  . HIS C 1 238 ? 30.082  6.485   1.140   1.00 39.56  ? 238 HIS C CG  1 
ATOM   9095  N ND1 . HIS C 1 238 ? 30.181  7.101   -0.085  1.00 41.58  ? 238 HIS C ND1 1 
ATOM   9096  C CD2 . HIS C 1 238 ? 31.290  5.949   1.389   1.00 39.52  ? 238 HIS C CD2 1 
ATOM   9097  C CE1 . HIS C 1 238 ? 31.411  6.940   -0.545  1.00 40.91  ? 238 HIS C CE1 1 
ATOM   9098  N NE2 . HIS C 1 238 ? 32.093  6.249   0.335   1.00 41.26  ? 238 HIS C NE2 1 
ATOM   9099  N N   . GLU C 1 239 ? 28.792  9.120   4.509   1.00 39.88  ? 239 GLU C N   1 
ATOM   9100  C CA  . GLU C 1 239 ? 28.582  10.549  4.686   1.00 44.27  ? 239 GLU C CA  1 
ATOM   9101  C C   . GLU C 1 239 ? 27.084  10.919  4.637   1.00 42.94  ? 239 GLU C C   1 
ATOM   9102  O O   . GLU C 1 239 ? 26.193  10.074  4.525   1.00 41.76  ? 239 GLU C O   1 
ATOM   9103  C CB  . GLU C 1 239 ? 29.412  11.307  3.640   1.00 47.00  ? 239 GLU C CB  1 
ATOM   9104  C CG  . GLU C 1 239 ? 30.752  11.776  4.162   1.00 55.89  ? 239 GLU C CG  1 
ATOM   9105  C CD  . GLU C 1 239 ? 31.494  12.843  3.361   1.00 53.59  ? 239 GLU C CD  1 
ATOM   9106  O OE1 . GLU C 1 239 ? 32.663  13.118  3.729   1.00 64.91  ? 239 GLU C OE1 1 
ATOM   9107  O OE2 . GLU C 1 239 ? 30.906  13.435  2.413   1.00 62.73  ? 239 GLU C OE2 1 
ATOM   9108  N N   . GLY C 1 240 ? 26.808  12.222  4.707   1.00 43.08  ? 240 GLY C N   1 
ATOM   9109  C CA  . GLY C 1 240 ? 25.450  12.719  4.766   1.00 39.67  ? 240 GLY C CA  1 
ATOM   9110  C C   . GLY C 1 240 ? 25.013  13.277  3.437   1.00 39.11  ? 240 GLY C C   1 
ATOM   9111  O O   . GLY C 1 240 ? 23.867  13.685  3.288   1.00 49.39  ? 240 GLY C O   1 
ATOM   9112  N N   . GLY C 1 241 ? 25.913  13.235  2.459   1.00 36.45  ? 241 GLY C N   1 
ATOM   9113  C CA  . GLY C 1 241 ? 25.745  14.015  1.245   1.00 34.06  ? 241 GLY C CA  1 
ATOM   9114  C C   . GLY C 1 241 ? 25.178  13.258  0.056   1.00 38.66  ? 241 GLY C C   1 
ATOM   9115  O O   . GLY C 1 241 ? 24.697  13.863  -0.907  1.00 42.74  ? 241 GLY C O   1 
ATOM   9116  N N   . ASN C 1 242 ? 25.224  11.931  0.101   1.00 41.13  ? 242 ASN C N   1 
ATOM   9117  C CA  . ASN C 1 242 ? 24.631  11.159  -0.982  1.00 41.75  ? 242 ASN C CA  1 
ATOM   9118  C C   . ASN C 1 242 ? 23.097  11.300  -0.932  1.00 39.68  ? 242 ASN C C   1 
ATOM   9119  O O   . ASN C 1 242 ? 22.517  11.653  0.080   1.00 43.25  ? 242 ASN C O   1 
ATOM   9120  C CB  . ASN C 1 242 ? 25.143  9.716   -0.927  1.00 42.04  ? 242 ASN C CB  1 
ATOM   9121  C CG  . ASN C 1 242 ? 24.659  8.969   0.293   1.00 39.25  ? 242 ASN C CG  1 
ATOM   9122  O OD1 . ASN C 1 242 ? 23.522  8.509   0.315   1.00 53.07  ? 242 ASN C OD1 1 
ATOM   9123  N ND2 . ASN C 1 242 ? 25.483  8.865   1.320   1.00 42.88  ? 242 ASN C ND2 1 
ATOM   9124  N N   . VAL C 1 243 ? 22.434  11.005  -2.047  1.00 37.55  ? 243 VAL C N   1 
ATOM   9125  C CA  . VAL C 1 243 ? 21.036  11.299  -2.242  1.00 34.98  ? 243 VAL C CA  1 
ATOM   9126  C C   . VAL C 1 243 ? 20.184  10.637  -1.157  1.00 32.53  ? 243 VAL C C   1 
ATOM   9127  O O   . VAL C 1 243 ? 19.286  11.254  -0.628  1.00 33.40  ? 243 VAL C O   1 
ATOM   9128  C CB  . VAL C 1 243 ? 20.579  10.890  -3.650  1.00 38.06  ? 243 VAL C CB  1 
ATOM   9129  C CG1 . VAL C 1 243 ? 19.061  10.801  -3.727  1.00 43.36  ? 243 VAL C CG1 1 
ATOM   9130  C CG2 . VAL C 1 243 ? 21.076  11.848  -4.713  1.00 35.94  ? 243 VAL C CG2 1 
ATOM   9131  N N   . SER C 1 244 ? 20.422  9.368   -0.855  1.00 35.32  ? 244 SER C N   1 
ATOM   9132  C CA  . SER C 1 244 ? 19.621  8.669   0.117   1.00 35.20  ? 244 SER C CA  1 
ATOM   9133  C C   . SER C 1 244 ? 19.822  9.292   1.508   1.00 38.95  ? 244 SER C C   1 
ATOM   9134  O O   . SER C 1 244 ? 18.852  9.618   2.187   1.00 43.82  ? 244 SER C O   1 
ATOM   9135  C CB  . SER C 1 244 ? 19.913  7.184   0.076   1.00 38.07  ? 244 SER C CB  1 
ATOM   9136  O OG  . SER C 1 244 ? 21.258  6.888   0.401   1.00 47.22  ? 244 SER C OG  1 
ATOM   9137  N N   . ALA C 1 245 ? 21.073  9.503   1.929   1.00 37.53  ? 245 ALA C N   1 
ATOM   9138  C CA  . ALA C 1 245 ? 21.350  10.024  3.264   1.00 36.83  ? 245 ALA C CA  1 
ATOM   9139  C C   . ALA C 1 245 ? 20.779  11.427  3.402   1.00 39.10  ? 245 ALA C C   1 
ATOM   9140  O O   . ALA C 1 245 ? 20.167  11.744  4.416   1.00 43.03  ? 245 ALA C O   1 
ATOM   9141  C CB  . ALA C 1 245 ? 22.817  10.004  3.582   1.00 38.53  ? 245 ALA C CB  1 
ATOM   9142  N N   . HIS C 1 246 ? 20.868  12.194  2.323   1.00 35.08  ? 246 HIS C N   1 
ATOM   9143  C CA  . HIS C 1 246 ? 20.502  13.588  2.360   1.00 34.91  ? 246 HIS C CA  1 
ATOM   9144  C C   . HIS C 1 246 ? 18.982  13.719  2.383   1.00 39.60  ? 246 HIS C C   1 
ATOM   9145  O O   . HIS C 1 246 ? 18.472  14.574  3.095   1.00 36.60  ? 246 HIS C O   1 
ATOM   9146  C CB  . HIS C 1 246 ? 21.157  14.323  1.187   1.00 34.09  ? 246 HIS C CB  1 
ATOM   9147  C CG  . HIS C 1 246 ? 20.849  15.778  1.113   1.00 37.25  ? 246 HIS C CG  1 
ATOM   9148  N ND1 . HIS C 1 246 ? 20.991  16.497  -0.054  1.00 39.37  ? 246 HIS C ND1 1 
ATOM   9149  C CD2 . HIS C 1 246 ? 20.349  16.646  2.034   1.00 37.62  ? 246 HIS C CD2 1 
ATOM   9150  C CE1 . HIS C 1 246 ? 20.616  17.772  0.167   1.00 41.78  ? 246 HIS C CE1 1 
ATOM   9151  N NE2 . HIS C 1 246 ? 20.207  17.877  1.428   1.00 36.10  ? 246 HIS C NE2 1 
ATOM   9152  N N   . THR C 1 247 ? 18.284  12.903  1.575   1.00 39.18  ? 247 THR C N   1 
ATOM   9153  C CA  . THR C 1 247 ? 16.835  12.862  1.582   1.00 37.78  ? 247 THR C CA  1 
ATOM   9154  C C   . THR C 1 247 ? 16.339  12.499  2.988   1.00 34.08  ? 247 THR C C   1 
ATOM   9155  O O   . THR C 1 247 ? 15.447  13.146  3.499   1.00 33.94  ? 247 THR C O   1 
ATOM   9156  C CB  . THR C 1 247 ? 16.279  11.867  0.568   1.00 36.34  ? 247 THR C CB  1 
ATOM   9157  O OG1 . THR C 1 247 ? 16.882  12.124  -0.708  1.00 36.33  ? 247 THR C OG1 1 
ATOM   9158  C CG2 . THR C 1 247 ? 14.765  11.913  0.507   1.00 34.85  ? 247 THR C CG2 1 
ATOM   9159  N N   . ASN C 1 248 ? 16.944  11.507  3.629   1.00 38.49  ? 248 ASN C N   1 
ATOM   9160  C CA  . ASN C 1 248 ? 16.600  11.151  4.999   1.00 34.45  ? 248 ASN C CA  1 
ATOM   9161  C C   . ASN C 1 248 ? 16.723  12.380  5.905   1.00 36.90  ? 248 ASN C C   1 
ATOM   9162  O O   . ASN C 1 248 ? 15.786  12.708  6.617   1.00 36.79  ? 248 ASN C O   1 
ATOM   9163  C CB  . ASN C 1 248 ? 17.455  9.995   5.478   1.00 32.15  ? 248 ASN C CB  1 
ATOM   9164  C CG  . ASN C 1 248 ? 17.112  9.532   6.873   1.00 36.83  ? 248 ASN C CG  1 
ATOM   9165  O OD1 . ASN C 1 248 ? 17.960  9.468   7.769   1.00 39.95  ? 248 ASN C OD1 1 
ATOM   9166  N ND2 . ASN C 1 248 ? 15.863  9.170   7.057   1.00 37.18  ? 248 ASN C ND2 1 
ATOM   9167  N N   . LEU C 1 249 ? 17.838  13.110  5.837   1.00 34.91  ? 249 LEU C N   1 
ATOM   9168  C CA  . LEU C 1 249 ? 18.077  14.210  6.765   1.00 40.13  ? 249 LEU C CA  1 
ATOM   9169  C C   . LEU C 1 249 ? 17.095  15.351  6.512   1.00 41.21  ? 249 LEU C C   1 
ATOM   9170  O O   . LEU C 1 249 ? 16.674  16.003  7.443   1.00 38.18  ? 249 LEU C O   1 
ATOM   9171  C CB  . LEU C 1 249 ? 19.495  14.748  6.557   1.00 41.52  ? 249 LEU C CB  1 
ATOM   9172  C CG  . LEU C 1 249 ? 20.597  13.895  7.145   1.00 44.49  ? 249 LEU C CG  1 
ATOM   9173  C CD1 . LEU C 1 249 ? 21.937  14.490  6.775   1.00 56.66  ? 249 LEU C CD1 1 
ATOM   9174  C CD2 . LEU C 1 249 ? 20.453  13.828  8.651   1.00 46.32  ? 249 LEU C CD2 1 
ATOM   9175  N N   . LEU C 1 250 ? 16.824  15.618  5.230   1.00 37.48  ? 250 LEU C N   1 
ATOM   9176  C CA  . LEU C 1 250 ? 15.954  16.679  4.796   1.00 39.01  ? 250 LEU C CA  1 
ATOM   9177  C C   . LEU C 1 250 ? 14.531  16.456  5.295   1.00 43.92  ? 250 LEU C C   1 
ATOM   9178  O O   . LEU C 1 250 ? 13.872  17.376  5.766   1.00 38.97  ? 250 LEU C O   1 
ATOM   9179  C CB  . LEU C 1 250 ? 15.974  16.711  3.273   1.00 40.14  ? 250 LEU C CB  1 
ATOM   9180  C CG  . LEU C 1 250 ? 15.097  17.765  2.605   1.00 40.08  ? 250 LEU C CG  1 
ATOM   9181  C CD1 . LEU C 1 250 ? 15.291  19.136  3.211   1.00 41.12  ? 250 LEU C CD1 1 
ATOM   9182  C CD2 . LEU C 1 250 ? 15.428  17.818  1.126   1.00 42.98  ? 250 LEU C CD2 1 
ATOM   9183  N N   . VAL C 1 251 ? 14.033  15.232  5.154   1.00 41.32  ? 251 VAL C N   1 
ATOM   9184  C CA  . VAL C 1 251 ? 12.668  15.001  5.549   1.00 35.15  ? 251 VAL C CA  1 
ATOM   9185  C C   . VAL C 1 251 ? 12.611  14.966  7.079   1.00 31.78  ? 251 VAL C C   1 
ATOM   9186  O O   . VAL C 1 251 ? 11.696  15.497  7.674   1.00 34.51  ? 251 VAL C O   1 
ATOM   9187  C CB  . VAL C 1 251 ? 12.110  13.762  4.851   1.00 33.20  ? 251 VAL C CB  1 
ATOM   9188  C CG1 . VAL C 1 251 ? 10.785  13.315  5.467   1.00 33.69  ? 251 VAL C CG1 1 
ATOM   9189  C CG2 . VAL C 1 251 ? 11.964  13.981  3.345   1.00 37.72  ? 251 VAL C CG2 1 
ATOM   9190  N N   . ASN C 1 252 ? 13.585  14.333  7.710   1.00 35.47  ? 252 ASN C N   1 
ATOM   9191  C CA  . ASN C 1 252 ? 13.758  14.346  9.157   1.00 35.39  ? 252 ASN C CA  1 
ATOM   9192  C C   . ASN C 1 252 ? 13.769  15.776  9.697   1.00 39.45  ? 252 ASN C C   1 
ATOM   9193  O O   . ASN C 1 252 ? 13.223  16.031  10.754  1.00 38.52  ? 252 ASN C O   1 
ATOM   9194  C CB  . ASN C 1 252 ? 15.069  13.666  9.542   1.00 35.27  ? 252 ASN C CB  1 
ATOM   9195  C CG  . ASN C 1 252 ? 15.399  13.750  11.024  1.00 43.43  ? 252 ASN C CG  1 
ATOM   9196  O OD1 . ASN C 1 252 ? 16.065  14.690  11.484  1.00 40.36  ? 252 ASN C OD1 1 
ATOM   9197  N ND2 . ASN C 1 252 ? 14.915  12.773  11.775  1.00 38.58  ? 252 ASN C ND2 1 
ATOM   9198  N N   . SER C 1 253 ? 14.361  16.718  8.956   1.00 39.56  ? 253 SER C N   1 
ATOM   9199  C CA  . SER C 1 253 ? 14.548  18.054  9.481   1.00 40.64  ? 253 SER C CA  1 
ATOM   9200  C C   . SER C 1 253 ? 13.214  18.721  9.756   1.00 42.42  ? 253 SER C C   1 
ATOM   9201  O O   . SER C 1 253 ? 13.198  19.677  10.533  1.00 43.15  ? 253 SER C O   1 
ATOM   9202  C CB  . SER C 1 253 ? 15.416  18.933  8.580   1.00 36.82  ? 253 SER C CB  1 
ATOM   9203  O OG  . SER C 1 253 ? 14.709  19.421  7.436   1.00 38.49  ? 253 SER C OG  1 
ATOM   9204  N N   . ALA C 1 254 ? 12.145  18.288  9.059   1.00 42.58  ? 254 ALA C N   1 
ATOM   9205  C CA  . ALA C 1 254 ? 10.801  18.829  9.295   1.00 41.78  ? 254 ALA C CA  1 
ATOM   9206  C C   . ALA C 1 254 ? 10.036  18.075  10.389  1.00 34.07  ? 254 ALA C C   1 
ATOM   9207  O O   . ALA C 1 254 ? 8.835   18.231  10.515  1.00 38.07  ? 254 ALA C O   1 
ATOM   9208  C CB  . ALA C 1 254 ? 10.015  18.798  8.012   1.00 43.27  ? 254 ALA C CB  1 
ATOM   9209  N N   . TYR C 1 255 ? 10.712  17.216  11.129  1.00 31.99  ? 255 TYR C N   1 
ATOM   9210  C CA  . TYR C 1 255 ? 10.148  16.417  12.200  1.00 39.28  ? 255 TYR C CA  1 
ATOM   9211  C C   . TYR C 1 255 ? 9.297   15.261  11.693  1.00 40.26  ? 255 TYR C C   1 
ATOM   9212  O O   . TYR C 1 255 ? 8.568   14.670  12.478  1.00 38.45  ? 255 TYR C O   1 
ATOM   9213  C CB  . TYR C 1 255 ? 9.385   17.267  13.214  1.00 46.66  ? 255 TYR C CB  1 
ATOM   9214  C CG  . TYR C 1 255 ? 10.215  18.141  14.132  1.00 46.82  ? 255 TYR C CG  1 
ATOM   9215  C CD1 . TYR C 1 255 ? 11.599  18.251  14.020  1.00 46.71  ? 255 TYR C CD1 1 
ATOM   9216  C CD2 . TYR C 1 255 ? 9.588   18.865  15.130  1.00 47.56  ? 255 TYR C CD2 1 
ATOM   9217  C CE1 . TYR C 1 255 ? 12.332  19.045  14.891  1.00 47.61  ? 255 TYR C CE1 1 
ATOM   9218  C CE2 . TYR C 1 255 ? 10.294  19.697  15.983  1.00 53.31  ? 255 TYR C CE2 1 
ATOM   9219  C CZ  . TYR C 1 255 ? 11.669  19.774  15.866  1.00 53.64  ? 255 TYR C CZ  1 
ATOM   9220  O OH  . TYR C 1 255 ? 12.311  20.607  16.710  1.00 46.53  ? 255 TYR C OH  1 
ATOM   9221  N N   . SER C 1 256 ? 9.474   14.863  10.426  1.00 39.61  ? 256 SER C N   1 
ATOM   9222  C CA  . SER C 1 256 ? 8.930   13.606  9.947   1.00 38.38  ? 256 SER C CA  1 
ATOM   9223  C C   . SER C 1 256 ? 9.699   12.439  10.555  1.00 38.62  ? 256 SER C C   1 
ATOM   9224  O O   . SER C 1 256 ? 10.923  12.478  10.631  1.00 36.09  ? 256 SER C O   1 
ATOM   9225  C CB  . SER C 1 256 ? 8.996   13.535  8.479   1.00 38.89  ? 256 SER C CB  1 
ATOM   9226  O OG  . SER C 1 256 ? 8.169   14.505  7.898   1.00 39.90  ? 256 SER C OG  1 
ATOM   9227  N N   . ASP C 1 257 ? 8.975   11.396  10.968  1.00 36.32  ? 257 ASP C N   1 
ATOM   9228  C CA  . ASP C 1 257 ? 9.559   10.224  11.622  1.00 38.80  ? 257 ASP C CA  1 
ATOM   9229  C C   . ASP C 1 257 ? 10.331  9.345   10.633  1.00 36.21  ? 257 ASP C C   1 
ATOM   9230  O O   . ASP C 1 257 ? 10.339  9.588   9.429   1.00 35.18  ? 257 ASP C O   1 
ATOM   9231  C CB  . ASP C 1 257 ? 8.457   9.401   12.289  1.00 44.51  ? 257 ASP C CB  1 
ATOM   9232  C CG  . ASP C 1 257 ? 7.463   8.857   11.274  1.00 46.24  ? 257 ASP C CG  1 
ATOM   9233  O OD1 . ASP C 1 257 ? 7.899   8.104   10.394  1.00 44.29  ? 257 ASP C OD1 1 
ATOM   9234  O OD2 . ASP C 1 257 ? 6.278   9.209   11.364  1.00 43.45  ? 257 ASP C OD2 1 
ATOM   9235  N N   . ILE C 1 258 ? 11.010  8.326   11.164  1.00 33.36  ? 258 ILE C N   1 
ATOM   9236  C CA  . ILE C 1 258 ? 11.961  7.530   10.404  1.00 35.10  ? 258 ILE C CA  1 
ATOM   9237  C C   . ILE C 1 258 ? 11.283  6.773   9.255   1.00 38.58  ? 258 ILE C C   1 
ATOM   9238  O O   . ILE C 1 258 ? 11.901  6.562   8.214   1.00 39.90  ? 258 ILE C O   1 
ATOM   9239  C CB  . ILE C 1 258 ? 12.742  6.578   11.332  1.00 35.78  ? 258 ILE C CB  1 
ATOM   9240  C CG1 . ILE C 1 258 ? 14.012  6.014   10.682  1.00 36.37  ? 258 ILE C CG1 1 
ATOM   9241  C CG2 . ILE C 1 258 ? 11.842  5.476   11.829  1.00 37.17  ? 258 ILE C CG2 1 
ATOM   9242  C CD1 . ILE C 1 258 ? 15.026  7.058   10.319  1.00 36.74  ? 258 ILE C CD1 1 
ATOM   9243  N N   . TYR C 1 259 ? 10.006  6.414   9.416   1.00 33.20  ? 259 TYR C N   1 
ATOM   9244  C CA  . TYR C 1 259 ? 9.272   5.699   8.395   1.00 30.53  ? 259 TYR C CA  1 
ATOM   9245  C C   . TYR C 1 259 ? 9.094   6.572   7.161   1.00 31.11  ? 259 TYR C C   1 
ATOM   9246  O O   . TYR C 1 259 ? 9.163   6.084   6.020   1.00 31.37  ? 259 TYR C O   1 
ATOM   9247  C CB  . TYR C 1 259 ? 7.938   5.228   8.965   1.00 29.55  ? 259 TYR C CB  1 
ATOM   9248  C CG  . TYR C 1 259 ? 8.076   4.240   10.086  1.00 26.78  ? 259 TYR C CG  1 
ATOM   9249  C CD1 . TYR C 1 259 ? 8.267   2.899   9.829   1.00 30.20  ? 259 TYR C CD1 1 
ATOM   9250  C CD2 . TYR C 1 259 ? 8.061   4.646   11.398  1.00 29.79  ? 259 TYR C CD2 1 
ATOM   9251  C CE1 . TYR C 1 259 ? 8.379   1.960   10.841  1.00 29.26  ? 259 TYR C CE1 1 
ATOM   9252  C CE2 . TYR C 1 259 ? 8.209   3.732   12.430  1.00 31.53  ? 259 TYR C CE2 1 
ATOM   9253  C CZ  . TYR C 1 259 ? 8.355   2.388   12.157  1.00 30.38  ? 259 TYR C CZ  1 
ATOM   9254  O OH  . TYR C 1 259 ? 8.564   1.482   13.163  1.00 35.36  ? 259 TYR C OH  1 
ATOM   9255  N N   . ARG C 1 260 ? 8.768   7.842   7.400   1.00 27.88  ? 260 ARG C N   1 
ATOM   9256  C CA  . ARG C 1 260 ? 8.656   8.822   6.326   1.00 29.93  ? 260 ARG C CA  1 
ATOM   9257  C C   . ARG C 1 260 ? 10.002  9.267   5.771   1.00 29.88  ? 260 ARG C C   1 
ATOM   9258  O O   . ARG C 1 260 ? 10.123  9.395   4.567   1.00 35.06  ? 260 ARG C O   1 
ATOM   9259  C CB  . ARG C 1 260 ? 7.846   10.019  6.802   1.00 34.75  ? 260 ARG C CB  1 
ATOM   9260  C CG  . ARG C 1 260 ? 6.352   9.761   6.819   1.00 34.52  ? 260 ARG C CG  1 
ATOM   9261  C CD  . ARG C 1 260 ? 5.607   10.866  7.561   1.00 33.96  ? 260 ARG C CD  1 
ATOM   9262  N NE  . ARG C 1 260 ? 4.159   10.871  7.357   1.00 34.75  ? 260 ARG C NE  1 
ATOM   9263  C CZ  . ARG C 1 260 ? 3.291   11.386  8.235   1.00 35.27  ? 260 ARG C CZ  1 
ATOM   9264  N NH1 . ARG C 1 260 ? 3.753   11.958  9.326   1.00 35.14  ? 260 ARG C NH1 1 
ATOM   9265  N NH2 . ARG C 1 260 ? 1.977   11.280  8.069   1.00 30.35  ? 260 ARG C NH2 1 
ATOM   9266  N N   . SER C 1 261 ? 11.033  9.472   6.607   1.00 32.90  ? 261 SER C N   1 
ATOM   9267  C CA  . SER C 1 261 ? 12.315  9.936   6.086   1.00 32.53  ? 261 SER C CA  1 
ATOM   9268  C C   . SER C 1 261 ? 13.062  8.819   5.354   1.00 33.19  ? 261 SER C C   1 
ATOM   9269  O O   . SER C 1 261 ? 13.634  9.056   4.290   1.00 32.27  ? 261 SER C O   1 
ATOM   9270  C CB  . SER C 1 261 ? 13.174  10.574  7.151   1.00 34.07  ? 261 SER C CB  1 
ATOM   9271  O OG  . SER C 1 261 ? 13.616  9.637   8.108   1.00 30.06  ? 261 SER C OG  1 
ATOM   9272  N N   . PHE C 1 262 ? 13.032  7.601   5.903   1.00 33.30  ? 262 PHE C N   1 
ATOM   9273  C CA  . PHE C 1 262 ? 13.722  6.492   5.282   1.00 36.64  ? 262 PHE C CA  1 
ATOM   9274  C C   . PHE C 1 262 ? 12.992  6.042   4.010   1.00 40.97  ? 262 PHE C C   1 
ATOM   9275  O O   . PHE C 1 262 ? 13.661  5.692   3.034   1.00 37.36  ? 262 PHE C O   1 
ATOM   9276  C CB  . PHE C 1 262 ? 13.971  5.334   6.257   1.00 37.36  ? 262 PHE C CB  1 
ATOM   9277  C CG  . PHE C 1 262 ? 14.882  4.286   5.682   1.00 36.07  ? 262 PHE C CG  1 
ATOM   9278  C CD1 . PHE C 1 262 ? 16.190  4.608   5.322   1.00 38.43  ? 262 PHE C CD1 1 
ATOM   9279  C CD2 . PHE C 1 262 ? 14.421  3.007   5.411   1.00 39.94  ? 262 PHE C CD2 1 
ATOM   9280  C CE1 . PHE C 1 262 ? 17.019  3.671   4.710   1.00 34.60  ? 262 PHE C CE1 1 
ATOM   9281  C CE2 . PHE C 1 262 ? 15.261  2.059   4.831   1.00 40.51  ? 262 PHE C CE2 1 
ATOM   9282  C CZ  . PHE C 1 262 ? 16.553  2.400   4.469   1.00 37.20  ? 262 PHE C CZ  1 
ATOM   9283  N N   . SER C 1 263 ? 11.649  6.093   3.979   1.00 35.70  ? 263 SER C N   1 
ATOM   9284  C CA  . SER C 1 263 ? 10.929  5.675   2.785   1.00 33.97  ? 263 SER C CA  1 
ATOM   9285  C C   . SER C 1 263 ? 11.160  6.657   1.629   1.00 33.61  ? 263 SER C C   1 
ATOM   9286  O O   . SER C 1 263 ? 11.400  6.244   0.498   1.00 37.59  ? 263 SER C O   1 
ATOM   9287  C CB  . SER C 1 263 ? 9.476   5.382   3.051   1.00 33.67  ? 263 SER C CB  1 
ATOM   9288  O OG  . SER C 1 263 ? 8.748   6.547   3.321   1.00 34.54  ? 263 SER C OG  1 
ATOM   9289  N N   . ALA C 1 264 ? 11.210  7.955   1.921   1.00 29.95  ? 264 ALA C N   1 
ATOM   9290  C CA  . ALA C 1 264 ? 11.585  8.955   0.950   1.00 29.97  ? 264 ALA C CA  1 
ATOM   9291  C C   . ALA C 1 264 ? 13.027  8.751   0.504   1.00 35.69  ? 264 ALA C C   1 
ATOM   9292  O O   . ALA C 1 264 ? 13.346  8.958   -0.662  1.00 37.51  ? 264 ALA C O   1 
ATOM   9293  C CB  . ALA C 1 264 ? 11.408  10.348  1.547   1.00 34.69  ? 264 ALA C CB  1 
ATOM   9294  N N   . ALA C 1 265 ? 13.909  8.377   1.437   1.00 30.44  ? 265 ALA C N   1 
ATOM   9295  C CA  . ALA C 1 265 ? 15.274  8.106   1.052   1.00 32.84  ? 265 ALA C CA  1 
ATOM   9296  C C   . ALA C 1 265 ? 15.358  6.981   0.019   1.00 36.62  ? 265 ALA C C   1 
ATOM   9297  O O   . ALA C 1 265 ? 16.243  7.046   -0.837  1.00 32.15  ? 265 ALA C O   1 
ATOM   9298  C CB  . ALA C 1 265 ? 16.096  7.760   2.247   1.00 30.76  ? 265 ALA C CB  1 
ATOM   9299  N N   . MET C 1 266 ? 14.515  5.935   0.155   1.00 34.63  ? 266 MET C N   1 
ATOM   9300  C CA  . MET C 1 266 ? 14.579  4.779   -0.740  1.00 34.83  ? 266 MET C CA  1 
ATOM   9301  C C   . MET C 1 266 ? 13.996  5.135   -2.110  1.00 36.71  ? 266 MET C C   1 
ATOM   9302  O O   . MET C 1 266 ? 14.356  4.544   -3.102  1.00 41.64  ? 266 MET C O   1 
ATOM   9303  C CB  . MET C 1 266 ? 13.810  3.593   -0.176  1.00 34.00  ? 266 MET C CB  1 
ATOM   9304  C CG  . MET C 1 266 ? 14.386  3.060   1.109   1.00 33.70  ? 266 MET C CG  1 
ATOM   9305  S SD  . MET C 1 266 ? 16.014  2.383   0.853   1.00 35.61  ? 266 MET C SD  1 
ATOM   9306  C CE  . MET C 1 266 ? 17.102  3.758   1.210   1.00 39.97  ? 266 MET C CE  1 
ATOM   9307  N N   . ASN C 1 267 ? 13.060  6.080   -2.166  1.00 36.72  ? 267 ASN C N   1 
ATOM   9308  C CA  . ASN C 1 267 ? 12.658  6.662   -3.432  1.00 36.40  ? 267 ASN C CA  1 
ATOM   9309  C C   . ASN C 1 267 ? 13.859  7.305   -4.153  1.00 41.84  ? 267 ASN C C   1 
ATOM   9310  O O   . ASN C 1 267 ? 13.914  7.382   -5.383  1.00 35.49  ? 267 ASN C O   1 
ATOM   9311  C CB  . ASN C 1 267 ? 11.530  7.654   -3.184  1.00 35.10  ? 267 ASN C CB  1 
ATOM   9312  C CG  . ASN C 1 267 ? 10.208  6.993   -2.847  1.00 33.63  ? 267 ASN C CG  1 
ATOM   9313  O OD1 . ASN C 1 267 ? 10.107  5.788   -2.747  1.00 34.36  ? 267 ASN C OD1 1 
ATOM   9314  N ND2 . ASN C 1 267 ? 9.151   7.774   -2.754  1.00 37.50  ? 267 ASN C ND2 1 
ATOM   9315  N N   . GLY C 1 268 ? 14.817  7.801   -3.364  1.00 39.27  ? 268 GLY C N   1 
ATOM   9316  C CA  . GLY C 1 268 ? 16.023  8.387   -3.896  1.00 35.11  ? 268 GLY C CA  1 
ATOM   9317  C C   . GLY C 1 268 ? 16.994  7.310   -4.359  1.00 36.28  ? 268 GLY C C   1 
ATOM   9318  O O   . GLY C 1 268 ? 17.555  7.386   -5.441  1.00 39.90  ? 268 GLY C O   1 
ATOM   9319  N N   . LEU C 1 269 ? 17.182  6.304   -3.518  1.00 35.42  ? 269 LEU C N   1 
ATOM   9320  C CA  . LEU C 1 269 ? 18.057  5.193   -3.807  1.00 33.32  ? 269 LEU C CA  1 
ATOM   9321  C C   . LEU C 1 269 ? 17.623  4.422   -5.047  1.00 33.09  ? 269 LEU C C   1 
ATOM   9322  O O   . LEU C 1 269 ? 18.463  3.804   -5.691  1.00 37.23  ? 269 LEU C O   1 
ATOM   9323  C CB  . LEU C 1 269 ? 18.083  4.282   -2.588  1.00 38.85  ? 269 LEU C CB  1 
ATOM   9324  C CG  . LEU C 1 269 ? 19.145  3.203   -2.676  1.00 41.47  ? 269 LEU C CG  1 
ATOM   9325  C CD1 . LEU C 1 269 ? 20.513  3.850   -2.795  1.00 48.57  ? 269 LEU C CD1 1 
ATOM   9326  C CD2 . LEU C 1 269 ? 19.072  2.301   -1.482  1.00 36.52  ? 269 LEU C CD2 1 
ATOM   9327  N N   . ALA C 1 270 ? 16.324  4.442   -5.343  1.00 32.18  ? 270 ALA C N   1 
ATOM   9328  C CA  . ALA C 1 270 ? 15.719  3.758   -6.484  1.00 36.74  ? 270 ALA C CA  1 
ATOM   9329  C C   . ALA C 1 270 ? 16.098  4.394   -7.825  1.00 36.05  ? 270 ALA C C   1 
ATOM   9330  O O   . ALA C 1 270 ? 15.853  3.812   -8.874  1.00 40.12  ? 270 ALA C O   1 
ATOM   9331  C CB  . ALA C 1 270 ? 14.203  3.767   -6.337  1.00 35.37  ? 270 ALA C CB  1 
ATOM   9332  N N   . GLY C 1 271 ? 16.591  5.637   -7.789  1.00 37.93  ? 271 GLY C N   1 
ATOM   9333  C CA  . GLY C 1 271 ? 16.956  6.360   -8.995  1.00 39.37  ? 271 GLY C CA  1 
ATOM   9334  C C   . GLY C 1 271 ? 18.146  5.709   -9.709  1.00 37.45  ? 271 GLY C C   1 
ATOM   9335  O O   . GLY C 1 271 ? 19.145  5.352   -9.077  1.00 36.35  ? 271 GLY C O   1 
ATOM   9336  N N   . PRO C 1 272 ? 18.080  5.560   -11.047 1.00 33.81  ? 272 PRO C N   1 
ATOM   9337  C CA  . PRO C 1 272 ? 19.218  5.116   -11.858 1.00 38.69  ? 272 PRO C CA  1 
ATOM   9338  C C   . PRO C 1 272 ? 20.614  5.608   -11.477 1.00 39.87  ? 272 PRO C C   1 
ATOM   9339  O O   . PRO C 1 272 ? 21.548  4.840   -11.488 1.00 44.62  ? 272 PRO C O   1 
ATOM   9340  C CB  . PRO C 1 272 ? 18.823  5.699   -13.204 1.00 40.20  ? 272 PRO C CB  1 
ATOM   9341  C CG  . PRO C 1 272 ? 17.327  5.440   -13.265 1.00 38.39  ? 272 PRO C CG  1 
ATOM   9342  C CD  . PRO C 1 272 ? 16.874  5.771   -11.859 1.00 40.85  ? 272 PRO C CD  1 
ATOM   9343  N N   . LEU C 1 273 ? 20.754  6.870   -11.078 1.00 45.01  ? 273 LEU C N   1 
ATOM   9344  C CA  . LEU C 1 273 ? 22.061  7.452   -10.821 1.00 46.59  ? 273 LEU C CA  1 
ATOM   9345  C C   . LEU C 1 273 ? 22.482  7.222   -9.381  1.00 48.33  ? 273 LEU C C   1 
ATOM   9346  O O   . LEU C 1 273 ? 23.564  7.650   -9.010  1.00 44.67  ? 273 LEU C O   1 
ATOM   9347  C CB  . LEU C 1 273 ? 22.024  8.960   -11.085 1.00 44.11  ? 273 LEU C CB  1 
ATOM   9348  C CG  . LEU C 1 273 ? 21.627  9.373   -12.494 1.00 46.04  ? 273 LEU C CG  1 
ATOM   9349  C CD1 . LEU C 1 273 ? 21.679  10.891  -12.676 1.00 46.60  ? 273 LEU C CD1 1 
ATOM   9350  C CD2 . LEU C 1 273 ? 22.541  8.704   -13.498 1.00 50.30  ? 273 LEU C CD2 1 
ATOM   9351  N N   . HIS C 1 274 ? 21.645  6.595   -8.549  1.00 49.08  ? 274 HIS C N   1 
ATOM   9352  C CA  . HIS C 1 274 ? 22.077  6.373   -7.179  1.00 44.62  ? 274 HIS C CA  1 
ATOM   9353  C C   . HIS C 1 274 ? 22.189  4.887   -6.857  1.00 40.64  ? 274 HIS C C   1 
ATOM   9354  O O   . HIS C 1 274 ? 23.142  4.521   -6.187  1.00 49.54  ? 274 HIS C O   1 
ATOM   9355  C CB  . HIS C 1 274 ? 21.177  7.109   -6.178  1.00 46.81  ? 274 HIS C CB  1 
ATOM   9356  C CG  . HIS C 1 274 ? 21.635  7.055   -4.757  1.00 44.49  ? 274 HIS C CG  1 
ATOM   9357  N ND1 . HIS C 1 274 ? 22.957  6.917   -4.407  1.00 41.92  ? 274 HIS C ND1 1 
ATOM   9358  C CD2 . HIS C 1 274 ? 20.971  7.237   -3.596  1.00 47.11  ? 274 HIS C CD2 1 
ATOM   9359  C CE1 . HIS C 1 274 ? 23.054  6.942   -3.074  1.00 40.36  ? 274 HIS C CE1 1 
ATOM   9360  N NE2 . HIS C 1 274 ? 21.864  7.146   -2.561  1.00 40.45  ? 274 HIS C NE2 1 
ATOM   9361  N N   . GLY C 1 275 ? 21.237  4.044   -7.273  1.00 36.78  ? 275 GLY C N   1 
ATOM   9362  C CA  . GLY C 1 275 ? 21.210  2.681   -6.745  1.00 46.23  ? 275 GLY C CA  1 
ATOM   9363  C C   . GLY C 1 275 ? 21.299  1.542   -7.767  1.00 45.83  ? 275 GLY C C   1 
ATOM   9364  O O   . GLY C 1 275 ? 21.057  0.405   -7.399  1.00 48.27  ? 275 GLY C O   1 
ATOM   9365  N N   . LEU C 1 276 ? 21.694  1.829   -9.012  1.00 41.35  ? 276 LEU C N   1 
ATOM   9366  C CA  . LEU C 1 276 ? 21.563  0.886   -10.110 1.00 46.54  ? 276 LEU C CA  1 
ATOM   9367  C C   . LEU C 1 276 ? 22.933  0.317   -10.545 1.00 46.76  ? 276 LEU C C   1 
ATOM   9368  O O   . LEU C 1 276 ? 22.986  -0.657  -11.299 1.00 40.07  ? 276 LEU C O   1 
ATOM   9369  C CB  . LEU C 1 276 ? 20.915  1.677   -11.255 1.00 50.38  ? 276 LEU C CB  1 
ATOM   9370  C CG  . LEU C 1 276 ? 19.719  1.088   -12.005 1.00 69.50  ? 276 LEU C CG  1 
ATOM   9371  C CD1 . LEU C 1 276 ? 19.694  1.617   -13.441 1.00 67.44  ? 276 LEU C CD1 1 
ATOM   9372  C CD2 . LEU C 1 276 ? 19.716  -0.432  -12.015 1.00 77.77  ? 276 LEU C CD2 1 
ATOM   9373  N N   . ALA C 1 277 ? 24.054  0.916   -10.100 1.00 39.48  ? 277 ALA C N   1 
ATOM   9374  C CA  . ALA C 1 277 ? 25.371  0.627   -10.667 1.00 49.11  ? 277 ALA C CA  1 
ATOM   9375  C C   . ALA C 1 277 ? 25.800  -0.835  -10.456 1.00 50.38  ? 277 ALA C C   1 
ATOM   9376  O O   . ALA C 1 277 ? 26.417  -1.444  -11.326 1.00 47.05  ? 277 ALA C O   1 
ATOM   9377  C CB  . ALA C 1 277 ? 26.399  1.584   -10.118 1.00 44.35  ? 277 ALA C CB  1 
ATOM   9378  N N   . ASN C 1 278 ? 25.503  -1.404  -9.289  1.00 45.67  ? 278 ASN C N   1 
ATOM   9379  C CA  . ASN C 1 278 ? 25.763  -2.815  -9.034  1.00 39.84  ? 278 ASN C CA  1 
ATOM   9380  C C   . ASN C 1 278 ? 25.231  -3.682  -10.189 1.00 39.87  ? 278 ASN C C   1 
ATOM   9381  O O   . ASN C 1 278 ? 25.957  -4.497  -10.722 1.00 38.28  ? 278 ASN C O   1 
ATOM   9382  C CB  . ASN C 1 278 ? 25.155  -3.200  -7.675  1.00 39.08  ? 278 ASN C CB  1 
ATOM   9383  C CG  . ASN C 1 278 ? 25.237  -4.673  -7.375  1.00 43.86  ? 278 ASN C CG  1 
ATOM   9384  O OD1 . ASN C 1 278 ? 25.657  -5.461  -8.218  1.00 57.52  ? 278 ASN C OD1 1 
ATOM   9385  N ND2 . ASN C 1 278 ? 24.825  -5.074  -6.190  1.00 45.30  ? 278 ASN C ND2 1 
ATOM   9386  N N   A GLN C 1 279 ? 23.953  -3.501  -10.557 0.25 39.26  ? 279 GLN C N   1 
ATOM   9387  N N   B GLN C 1 279 ? 23.944  -3.527  -10.547 0.25 35.66  ? 279 GLN C N   1 
ATOM   9388  N N   C GLN C 1 279 ? 23.951  -3.497  -10.538 0.50 39.36  ? 279 GLN C N   1 
ATOM   9389  C CA  A GLN C 1 279 ? 23.337  -4.299  -11.604 0.25 37.55  ? 279 GLN C CA  1 
ATOM   9390  C CA  B GLN C 1 279 ? 23.349  -4.328  -11.605 0.25 31.67  ? 279 GLN C CA  1 
ATOM   9391  C CA  C GLN C 1 279 ? 23.302  -4.258  -11.584 0.50 36.39  ? 279 GLN C CA  1 
ATOM   9392  C C   A GLN C 1 279 ? 24.061  -4.064  -12.929 0.25 38.37  ? 279 GLN C C   1 
ATOM   9393  C C   B GLN C 1 279 ? 24.065  -4.067  -12.931 0.25 34.99  ? 279 GLN C C   1 
ATOM   9394  C C   C GLN C 1 279 ? 24.025  -4.050  -12.919 0.50 37.46  ? 279 GLN C C   1 
ATOM   9395  O O   A GLN C 1 279 ? 24.285  -4.998  -13.693 0.25 37.35  ? 279 GLN C O   1 
ATOM   9396  O O   B GLN C 1 279 ? 24.290  -4.991  -13.706 0.25 34.37  ? 279 GLN C O   1 
ATOM   9397  O O   C GLN C 1 279 ? 24.213  -4.985  -13.689 0.50 35.55  ? 279 GLN C O   1 
ATOM   9398  C CB  A GLN C 1 279 ? 21.866  -3.919  -11.790 0.25 38.77  ? 279 GLN C CB  1 
ATOM   9399  C CB  B GLN C 1 279 ? 21.855  -4.034  -11.797 0.25 28.56  ? 279 GLN C CB  1 
ATOM   9400  C CB  C GLN C 1 279 ? 21.844  -3.794  -11.674 0.50 38.97  ? 279 GLN C CB  1 
ATOM   9401  C CG  A GLN C 1 279 ? 21.221  -3.331  -10.549 0.25 38.39  ? 279 GLN C CG  1 
ATOM   9402  C CG  B GLN C 1 279 ? 21.389  -4.371  -13.211 0.25 24.66  ? 279 GLN C CG  1 
ATOM   9403  C CG  C GLN C 1 279 ? 21.010  -4.147  -10.453 0.50 40.19  ? 279 GLN C CG  1 
ATOM   9404  C CD  A GLN C 1 279 ? 19.717  -3.325  -10.638 0.25 36.39  ? 279 GLN C CD  1 
ATOM   9405  C CD  B GLN C 1 279 ? 19.913  -4.236  -13.481 0.25 20.55  ? 279 GLN C CD  1 
ATOM   9406  C CD  C GLN C 1 279 ? 20.861  -3.100  -9.365  0.50 34.17  ? 279 GLN C CD  1 
ATOM   9407  O OE1 A GLN C 1 279 ? 19.132  -3.637  -11.678 0.25 36.65  ? 279 GLN C OE1 1 
ATOM   9408  O OE1 B GLN C 1 279 ? 19.441  -4.655  -14.529 0.25 18.30  ? 279 GLN C OE1 1 
ATOM   9409  O OE1 C GLN C 1 279 ? 21.827  -2.618  -8.755  0.50 29.29  ? 279 GLN C OE1 1 
ATOM   9410  N NE2 A GLN C 1 279 ? 19.089  -2.991  -9.523  0.25 33.55  ? 279 GLN C NE2 1 
ATOM   9411  N NE2 B GLN C 1 279 ? 19.165  -3.712  -12.529 0.25 19.07  ? 279 GLN C NE2 1 
ATOM   9412  N NE2 C GLN C 1 279 ? 19.604  -2.824  -9.052  0.50 27.65  ? 279 GLN C NE2 1 
ATOM   9413  N N   . GLU C 1 280 ? 24.402  -2.799  -13.198 1.00 38.71  ? 280 GLU C N   1 
ATOM   9414  C CA  . GLU C 1 280 ? 24.941  -2.403  -14.489 1.00 46.34  ? 280 GLU C CA  1 
ATOM   9415  C C   . GLU C 1 280 ? 26.316  -3.026  -14.657 1.00 45.93  ? 280 GLU C C   1 
ATOM   9416  O O   . GLU C 1 280 ? 26.676  -3.473  -15.757 1.00 45.95  ? 280 GLU C O   1 
ATOM   9417  C CB  . GLU C 1 280 ? 24.977  -0.872  -14.639 1.00 54.96  ? 280 GLU C CB  1 
ATOM   9418  C CG  . GLU C 1 280 ? 23.635  -0.252  -15.046 1.00 65.01  ? 280 GLU C CG  1 
ATOM   9419  C CD  . GLU C 1 280 ? 23.365  1.245   -14.808 1.00 76.29  ? 280 GLU C CD  1 
ATOM   9420  O OE1 . GLU C 1 280 ? 22.337  1.734   -15.356 1.00 79.43  ? 280 GLU C OE1 1 
ATOM   9421  O OE2 . GLU C 1 280 ? 24.110  1.926   -14.031 1.00 56.55  ? 280 GLU C OE2 1 
ATOM   9422  N N   . VAL C 1 281 ? 27.064  -3.066  -13.548 1.00 41.06  ? 281 VAL C N   1 
ATOM   9423  C CA  . VAL C 1 281 ? 28.398  -3.620  -13.600 1.00 35.89  ? 281 VAL C CA  1 
ATOM   9424  C C   . VAL C 1 281 ? 28.265  -5.080  -13.973 1.00 39.55  ? 281 VAL C C   1 
ATOM   9425  O O   . VAL C 1 281 ? 28.884  -5.525  -14.946 1.00 40.36  ? 281 VAL C O   1 
ATOM   9426  C CB  . VAL C 1 281 ? 29.157  -3.446  -12.282 1.00 35.01  ? 281 VAL C CB  1 
ATOM   9427  C CG1 . VAL C 1 281 ? 30.376  -4.362  -12.205 1.00 33.71  ? 281 VAL C CG1 1 
ATOM   9428  C CG2 . VAL C 1 281 ? 29.552  -1.984  -12.065 1.00 36.86  ? 281 VAL C CG2 1 
ATOM   9429  N N   . LEU C 1 282 ? 27.433  -5.788  -13.207 1.00 37.21  ? 282 LEU C N   1 
ATOM   9430  C CA  . LEU C 1 282 ? 27.348  -7.226  -13.335 1.00 40.77  ? 282 LEU C CA  1 
ATOM   9431  C C   . LEU C 1 282 ? 26.897  -7.622  -14.743 1.00 43.32  ? 282 LEU C C   1 
ATOM   9432  O O   . LEU C 1 282 ? 27.419  -8.575  -15.304 1.00 45.06  ? 282 LEU C O   1 
ATOM   9433  C CB  . LEU C 1 282 ? 26.400  -7.799  -12.288 1.00 38.59  ? 282 LEU C CB  1 
ATOM   9434  C CG  . LEU C 1 282 ? 26.066  -9.282  -12.482 1.00 37.73  ? 282 LEU C CG  1 
ATOM   9435  C CD1 . LEU C 1 282 ? 27.334  -10.098 -12.395 1.00 36.11  ? 282 LEU C CD1 1 
ATOM   9436  C CD2 . LEU C 1 282 ? 25.053  -9.772  -11.445 1.00 38.15  ? 282 LEU C CD2 1 
ATOM   9437  N N   . ARG C 1 283 ? 25.909  -6.925  -15.292 1.00 45.81  ? 283 ARG C N   1 
ATOM   9438  C CA  . ARG C 1 283 ? 25.463  -7.171  -16.656 1.00 49.54  ? 283 ARG C CA  1 
ATOM   9439  C C   . ARG C 1 283 ? 26.605  -6.942  -17.640 1.00 46.09  ? 283 ARG C C   1 
ATOM   9440  O O   . ARG C 1 283 ? 26.757  -7.676  -18.608 1.00 43.17  ? 283 ARG C O   1 
ATOM   9441  C CB  . ARG C 1 283 ? 24.293  -6.252  -17.036 1.00 52.63  ? 283 ARG C CB  1 
ATOM   9442  C CG  . ARG C 1 283 ? 22.951  -6.652  -16.424 1.00 55.72  ? 283 ARG C CG  1 
ATOM   9443  C CD  . ARG C 1 283 ? 21.827  -5.883  -17.100 1.00 59.48  ? 283 ARG C CD  1 
ATOM   9444  N NE  . ARG C 1 283 ? 20.552  -5.965  -16.410 1.00 57.25  ? 283 ARG C NE  1 
ATOM   9445  C CZ  . ARG C 1 283 ? 19.696  -6.979  -16.479 1.00 59.53  ? 283 ARG C CZ  1 
ATOM   9446  N NH1 . ARG C 1 283 ? 19.928  -8.036  -17.238 1.00 56.85  ? 283 ARG C NH1 1 
ATOM   9447  N NH2 . ARG C 1 283 ? 18.576  -6.919  -15.785 1.00 64.44  ? 283 ARG C NH2 1 
ATOM   9448  N N   . TRP C 1 284 ? 27.404  -5.913  -17.384 1.00 46.10  ? 284 TRP C N   1 
ATOM   9449  C CA  . TRP C 1 284 ? 28.524  -5.584  -18.241 1.00 42.92  ? 284 TRP C CA  1 
ATOM   9450  C C   . TRP C 1 284 ? 29.551  -6.712  -18.203 1.00 45.64  ? 284 TRP C C   1 
ATOM   9451  O O   . TRP C 1 284 ? 30.064  -7.146  -19.240 1.00 42.64  ? 284 TRP C O   1 
ATOM   9452  C CB  . TRP C 1 284 ? 29.121  -4.259  -17.773 1.00 38.06  ? 284 TRP C CB  1 
ATOM   9453  C CG  . TRP C 1 284 ? 30.145  -3.657  -18.671 1.00 40.51  ? 284 TRP C CG  1 
ATOM   9454  C CD1 . TRP C 1 284 ? 29.914  -2.930  -19.808 1.00 41.42  ? 284 TRP C CD1 1 
ATOM   9455  C CD2 . TRP C 1 284 ? 31.576  -3.642  -18.451 1.00 41.12  ? 284 TRP C CD2 1 
ATOM   9456  N NE1 . TRP C 1 284 ? 31.114  -2.506  -20.328 1.00 43.13  ? 284 TRP C NE1 1 
ATOM   9457  C CE2 . TRP C 1 284 ? 32.148  -2.922  -19.521 1.00 40.69  ? 284 TRP C CE2 1 
ATOM   9458  C CE3 . TRP C 1 284 ? 32.429  -4.183  -17.483 1.00 41.78  ? 284 TRP C CE3 1 
ATOM   9459  C CZ2 . TRP C 1 284 ? 33.532  -2.756  -19.654 1.00 45.28  ? 284 TRP C CZ2 1 
ATOM   9460  C CZ3 . TRP C 1 284 ? 33.796  -4.025  -17.618 1.00 40.91  ? 284 TRP C CZ3 1 
ATOM   9461  C CH2 . TRP C 1 284 ? 34.337  -3.289  -18.671 1.00 41.30  ? 284 TRP C CH2 1 
ATOM   9462  N N   . ILE C 1 285 ? 29.845  -7.184  -16.986 1.00 44.69  ? 285 ILE C N   1 
ATOM   9463  C CA  . ILE C 1 285 ? 30.790  -8.274  -16.789 1.00 41.66  ? 285 ILE C CA  1 
ATOM   9464  C C   . ILE C 1 285 ? 30.312  -9.528  -17.519 1.00 43.63  ? 285 ILE C C   1 
ATOM   9465  O O   . ILE C 1 285 ? 31.134  -10.189 -18.151 1.00 38.17  ? 285 ILE C O   1 
ATOM   9466  C CB  . ILE C 1 285 ? 31.044  -8.529  -15.295 1.00 39.09  ? 285 ILE C CB  1 
ATOM   9467  C CG1 . ILE C 1 285 ? 31.772  -7.353  -14.635 1.00 39.90  ? 285 ILE C CG1 1 
ATOM   9468  C CG2 . ILE C 1 285 ? 31.787  -9.828  -15.069 1.00 37.90  ? 285 ILE C CG2 1 
ATOM   9469  C CD1 . ILE C 1 285 ? 33.237  -7.226  -14.975 1.00 41.70  ? 285 ILE C CD1 1 
ATOM   9470  N N   . GLN C 1 286 ? 28.994  -9.804  -17.496 1.00 43.04  ? 286 GLN C N   1 
ATOM   9471  C CA  . GLN C 1 286 ? 28.435  -10.999 -18.126 1.00 43.60  ? 286 GLN C CA  1 
ATOM   9472  C C   . GLN C 1 286 ? 28.450  -10.877 -19.653 1.00 40.50  ? 286 GLN C C   1 
ATOM   9473  O O   . GLN C 1 286 ? 28.513  -11.879 -20.373 1.00 38.46  ? 286 GLN C O   1 
ATOM   9474  C CB  . GLN C 1 286 ? 27.014  -11.255 -17.619 1.00 41.14  ? 286 GLN C CB  1 
ATOM   9475  C CG  . GLN C 1 286 ? 26.969  -11.553 -16.120 1.00 41.75  ? 286 GLN C CG  1 
ATOM   9476  C CD  . GLN C 1 286 ? 25.566  -11.533 -15.585 1.00 43.70  ? 286 GLN C CD  1 
ATOM   9477  O OE1 . GLN C 1 286 ? 24.835  -10.559 -15.742 1.00 49.15  ? 286 GLN C OE1 1 
ATOM   9478  N NE2 . GLN C 1 286 ? 25.153  -12.641 -14.997 1.00 49.39  ? 286 GLN C NE2 1 
ATOM   9479  N N   . MET C 1 287 ? 28.365  -9.635  -20.123 1.00 40.90  ? 287 MET C N   1 
ATOM   9480  C CA  . MET C 1 287 ? 28.451  -9.308  -21.536 1.00 43.29  ? 287 MET C CA  1 
ATOM   9481  C C   . MET C 1 287 ? 29.880  -9.575  -22.011 1.00 47.80  ? 287 MET C C   1 
ATOM   9482  O O   . MET C 1 287 ? 30.036  -10.159 -23.074 1.00 47.58  ? 287 MET C O   1 
ATOM   9483  C CB  . MET C 1 287 ? 28.024  -7.855  -21.786 1.00 44.56  ? 287 MET C CB  1 
ATOM   9484  C CG  . MET C 1 287 ? 28.269  -7.341  -23.206 1.00 50.63  ? 287 MET C CG  1 
ATOM   9485  S SD  . MET C 1 287 ? 29.998  -6.814  -23.492 1.00 60.26  ? 287 MET C SD  1 
ATOM   9486  C CE  . MET C 1 287 ? 30.057  -5.280  -22.564 1.00 58.19  ? 287 MET C CE  1 
ATOM   9487  N N   . LEU C 1 288 ? 30.909  -9.259  -21.198 1.00 48.49  ? 288 LEU C N   1 
ATOM   9488  C CA  . LEU C 1 288 ? 32.281  -9.622  -21.547 1.00 45.60  ? 288 LEU C CA  1 
ATOM   9489  C C   . LEU C 1 288 ? 32.424  -11.140 -21.665 1.00 57.37  ? 288 LEU C C   1 
ATOM   9490  O O   . LEU C 1 288 ? 32.985  -11.641 -22.648 1.00 48.50  ? 288 LEU C O   1 
ATOM   9491  C CB  . LEU C 1 288 ? 33.299  -9.068  -20.545 1.00 40.35  ? 288 LEU C CB  1 
ATOM   9492  C CG  . LEU C 1 288 ? 33.402  -7.534  -20.504 1.00 47.67  ? 288 LEU C CG  1 
ATOM   9493  C CD1 . LEU C 1 288 ? 34.303  -7.045  -19.373 1.00 49.87  ? 288 LEU C CD1 1 
ATOM   9494  C CD2 . LEU C 1 288 ? 33.911  -6.972  -21.813 1.00 51.31  ? 288 LEU C CD2 1 
ATOM   9495  N N   . TYR C 1 289 ? 31.948  -11.870 -20.651 1.00 55.04  ? 289 TYR C N   1 
ATOM   9496  C CA  . TYR C 1 289 ? 32.063  -13.318 -20.639 1.00 47.81  ? 289 TYR C CA  1 
ATOM   9497  C C   . TYR C 1 289 ? 31.562  -13.914 -21.955 1.00 46.10  ? 289 TYR C C   1 
ATOM   9498  O O   . TYR C 1 289 ? 32.229  -14.753 -22.555 1.00 47.76  ? 289 TYR C O   1 
ATOM   9499  C CB  . TYR C 1 289 ? 31.265  -13.905 -19.479 1.00 51.73  ? 289 TYR C CB  1 
ATOM   9500  C CG  . TYR C 1 289 ? 31.549  -15.358 -19.232 1.00 53.64  ? 289 TYR C CG  1 
ATOM   9501  C CD1 . TYR C 1 289 ? 32.713  -15.738 -18.590 1.00 50.35  ? 289 TYR C CD1 1 
ATOM   9502  C CD2 . TYR C 1 289 ? 30.678  -16.351 -19.656 1.00 61.64  ? 289 TYR C CD2 1 
ATOM   9503  C CE1 . TYR C 1 289 ? 32.994  -17.072 -18.359 1.00 55.71  ? 289 TYR C CE1 1 
ATOM   9504  C CE2 . TYR C 1 289 ? 30.938  -17.696 -19.426 1.00 64.68  ? 289 TYR C CE2 1 
ATOM   9505  C CZ  . TYR C 1 289 ? 32.111  -18.053 -18.780 1.00 70.32  ? 289 TYR C CZ  1 
ATOM   9506  O OH  . TYR C 1 289 ? 32.456  -19.356 -18.537 1.00 78.17  ? 289 TYR C OH  1 
ATOM   9507  N N   . LYS C 1 290 ? 30.372  -13.489 -22.389 1.00 47.12  ? 290 LYS C N   1 
ATOM   9508  C CA  . LYS C 1 290 ? 29.688  -14.060 -23.540 1.00 53.37  ? 290 LYS C CA  1 
ATOM   9509  C C   . LYS C 1 290 ? 30.400  -13.692 -24.850 1.00 53.14  ? 290 LYS C C   1 
ATOM   9510  O O   . LYS C 1 290 ? 30.518  -14.514 -25.744 1.00 50.70  ? 290 LYS C O   1 
ATOM   9511  C CB  . LYS C 1 290 ? 28.246  -13.546 -23.578 1.00 57.33  ? 290 LYS C CB  1 
ATOM   9512  C CG  . LYS C 1 290 ? 27.357  -14.212 -24.609 1.00 60.28  ? 290 LYS C CG  1 
ATOM   9513  C CD  . LYS C 1 290 ? 26.045  -13.509 -24.776 1.00 68.59  ? 290 LYS C CD  1 
ATOM   9514  C CE  . LYS C 1 290 ? 25.132  -14.191 -25.772 1.00 70.21  ? 290 LYS C CE  1 
ATOM   9515  N NZ  . LYS C 1 290 ? 23.874  -13.425 -25.945 1.00 73.56  ? 290 LYS C NZ  1 
ATOM   9516  N N   . LYS C 1 291 ? 30.870  -12.448 -24.952 1.00 56.47  ? 291 LYS C N   1 
ATOM   9517  C CA  . LYS C 1 291 ? 31.476  -11.925 -26.166 1.00 58.37  ? 291 LYS C CA  1 
ATOM   9518  C C   . LYS C 1 291 ? 32.800  -12.645 -26.444 1.00 59.78  ? 291 LYS C C   1 
ATOM   9519  O O   . LYS C 1 291 ? 33.067  -12.985 -27.582 1.00 49.79  ? 291 LYS C O   1 
ATOM   9520  C CB  . LYS C 1 291 ? 31.669  -10.410 -26.034 1.00 53.62  ? 291 LYS C CB  1 
ATOM   9521  C CG  . LYS C 1 291 ? 32.251  -9.693  -27.248 1.00 55.07  ? 291 LYS C CG  1 
ATOM   9522  C CD  . LYS C 1 291 ? 32.560  -8.226  -26.970 1.00 68.33  ? 291 LYS C CD  1 
ATOM   9523  C CE  . LYS C 1 291 ? 33.381  -7.533  -28.048 1.00 73.74  ? 291 LYS C CE  1 
ATOM   9524  N NZ  . LYS C 1 291 ? 32.627  -7.387  -29.314 1.00 70.71  ? 291 LYS C NZ  1 
ATOM   9525  N N   . PHE C 1 292 ? 33.623  -12.859 -25.408 1.00 50.50  ? 292 PHE C N   1 
ATOM   9526  C CA  . PHE C 1 292 ? 34.929  -13.471 -25.568 1.00 53.14  ? 292 PHE C CA  1 
ATOM   9527  C C   . PHE C 1 292 ? 34.874  -14.958 -25.218 1.00 53.25  ? 292 PHE C C   1 
ATOM   9528  O O   . PHE C 1 292 ? 35.918  -15.576 -25.045 1.00 54.89  ? 292 PHE C O   1 
ATOM   9529  C CB  . PHE C 1 292 ? 35.960  -12.718 -24.714 1.00 55.24  ? 292 PHE C CB  1 
ATOM   9530  C CG  . PHE C 1 292 ? 36.151  -11.281 -25.145 1.00 53.49  ? 292 PHE C CG  1 
ATOM   9531  C CD1 . PHE C 1 292 ? 36.851  -10.980 -26.301 1.00 54.87  ? 292 PHE C CD1 1 
ATOM   9532  C CD2 . PHE C 1 292 ? 35.584  -10.237 -24.436 1.00 52.01  ? 292 PHE C CD2 1 
ATOM   9533  C CE1 . PHE C 1 292 ? 36.993  -9.670  -26.720 1.00 50.74  ? 292 PHE C CE1 1 
ATOM   9534  C CE2 . PHE C 1 292 ? 35.727  -8.928  -24.853 1.00 52.50  ? 292 PHE C CE2 1 
ATOM   9535  C CZ  . PHE C 1 292 ? 36.427  -8.645  -25.999 1.00 60.12  ? 292 PHE C CZ  1 
ATOM   9536  N N   . GLY C 1 293 ? 33.665  -15.527 -25.109 1.00 49.05  ? 293 GLY C N   1 
ATOM   9537  C CA  . GLY C 1 293 ? 33.508  -16.935 -24.798 1.00 48.60  ? 293 GLY C CA  1 
ATOM   9538  C C   . GLY C 1 293 ? 34.377  -17.366 -23.616 1.00 52.71  ? 293 GLY C C   1 
ATOM   9539  O O   . GLY C 1 293 ? 34.919  -18.456 -23.620 1.00 58.18  ? 293 GLY C O   1 
ATOM   9540  N N   . GLY C 1 294 ? 34.453  -16.526 -22.578 1.00 52.60  ? 294 GLY C N   1 
ATOM   9541  C CA  . GLY C 1 294 ? 35.268  -16.796 -21.406 1.00 48.87  ? 294 GLY C CA  1 
ATOM   9542  C C   . GLY C 1 294 ? 35.935  -15.520 -20.874 1.00 52.15  ? 294 GLY C C   1 
ATOM   9543  O O   . GLY C 1 294 ? 35.584  -14.401 -21.215 1.00 50.08  ? 294 GLY C O   1 
ATOM   9544  N N   . VAL C 1 295 ? 36.906  -15.705 -20.006 1.00 49.64  ? 295 VAL C N   1 
ATOM   9545  C CA  . VAL C 1 295 ? 37.657  -14.593 -19.485 1.00 48.87  ? 295 VAL C CA  1 
ATOM   9546  C C   . VAL C 1 295 ? 38.527  -14.043 -20.605 1.00 57.41  ? 295 VAL C C   1 
ATOM   9547  O O   . VAL C 1 295 ? 39.355  -14.767 -21.156 1.00 55.00  ? 295 VAL C O   1 
ATOM   9548  C CB  . VAL C 1 295 ? 38.528  -15.047 -18.308 1.00 48.06  ? 295 VAL C CB  1 
ATOM   9549  C CG1 . VAL C 1 295 ? 39.318  -13.878 -17.746 1.00 52.43  ? 295 VAL C CG1 1 
ATOM   9550  C CG2 . VAL C 1 295 ? 37.691  -15.729 -17.229 1.00 49.38  ? 295 VAL C CG2 1 
ATOM   9551  N N   . PRO C 1 296 ? 38.409  -12.743 -20.947 1.00 57.84  ? 296 PRO C N   1 
ATOM   9552  C CA  . PRO C 1 296 ? 39.343  -12.131 -21.889 1.00 54.77  ? 296 PRO C CA  1 
ATOM   9553  C C   . PRO C 1 296 ? 40.792  -12.072 -21.396 1.00 54.93  ? 296 PRO C C   1 
ATOM   9554  O O   . PRO C 1 296 ? 41.084  -12.157 -20.207 1.00 59.82  ? 296 PRO C O   1 
ATOM   9555  C CB  . PRO C 1 296 ? 38.746  -10.728 -22.117 1.00 58.87  ? 296 PRO C CB  1 
ATOM   9556  C CG  . PRO C 1 296 ? 37.916  -10.457 -20.888 1.00 59.50  ? 296 PRO C CG  1 
ATOM   9557  C CD  . PRO C 1 296 ? 37.373  -11.811 -20.475 1.00 51.89  ? 296 PRO C CD  1 
ATOM   9558  N N   . THR C 1 297 ? 41.712  -11.997 -22.355 1.00 53.97  ? 297 THR C N   1 
ATOM   9559  C CA  . THR C 1 297 ? 43.097  -11.627 -22.107 1.00 50.77  ? 297 THR C CA  1 
ATOM   9560  C C   . THR C 1 297 ? 43.178  -10.121 -21.831 1.00 50.40  ? 297 THR C C   1 
ATOM   9561  O O   . THR C 1 297 ? 42.283  -9.362  -22.206 1.00 48.41  ? 297 THR C O   1 
ATOM   9562  C CB  . THR C 1 297 ? 43.934  -12.002 -23.346 1.00 56.94  ? 297 THR C CB  1 
ATOM   9563  O OG1 . THR C 1 297 ? 43.439  -11.264 -24.474 1.00 49.78  ? 297 THR C OG1 1 
ATOM   9564  C CG2 . THR C 1 297 ? 43.876  -13.479 -23.680 1.00 57.66  ? 297 THR C CG2 1 
ATOM   9565  N N   . LYS C 1 298 ? 44.286  -9.667  -21.240 1.00 52.74  ? 298 LYS C N   1 
ATOM   9566  C CA  . LYS C 1 298 ? 44.460  -8.258  -20.938 1.00 60.60  ? 298 LYS C CA  1 
ATOM   9567  C C   . LYS C 1 298 ? 44.259  -7.435  -22.215 1.00 63.51  ? 298 LYS C C   1 
ATOM   9568  O O   . LYS C 1 298 ? 43.640  -6.365  -22.186 1.00 60.11  ? 298 LYS C O   1 
ATOM   9569  C CB  . LYS C 1 298 ? 45.829  -8.028  -20.284 1.00 66.91  ? 298 LYS C CB  1 
ATOM   9570  C CG  . LYS C 1 298 ? 45.998  -8.637  -18.895 1.00 75.75  ? 298 LYS C CG  1 
ATOM   9571  C CD  . LYS C 1 298 ? 47.307  -8.270  -18.225 1.00 89.18  ? 298 LYS C CD  1 
ATOM   9572  C CE  . LYS C 1 298 ? 48.515  -8.809  -18.972 1.00 110.10 ? 298 LYS C CE  1 
ATOM   9573  N NZ  . LYS C 1 298 ? 49.803  -8.415  -18.345 1.00 112.73 ? 298 LYS C NZ  1 
ATOM   9574  N N   . GLU C 1 299 ? 44.726  -7.994  -23.338 1.00 64.30  ? 299 GLU C N   1 
ATOM   9575  C CA  . GLU C 1 299 ? 44.769  -7.320  -24.625 1.00 69.11  ? 299 GLU C CA  1 
ATOM   9576  C C   . GLU C 1 299 ? 43.343  -7.137  -25.134 1.00 60.40  ? 299 GLU C C   1 
ATOM   9577  O O   . GLU C 1 299 ? 42.923  -6.031  -25.491 1.00 58.80  ? 299 GLU C O   1 
ATOM   9578  C CB  . GLU C 1 299 ? 45.619  -8.125  -25.624 1.00 90.42  ? 299 GLU C CB  1 
ATOM   9579  C CG  . GLU C 1 299 ? 47.046  -8.425  -25.140 1.00 107.51 ? 299 GLU C CG  1 
ATOM   9580  C CD  . GLU C 1 299 ? 47.218  -9.572  -24.140 1.00 114.83 ? 299 GLU C CD  1 
ATOM   9581  O OE1 . GLU C 1 299 ? 47.493  -9.302  -22.945 1.00 105.27 ? 299 GLU C OE1 1 
ATOM   9582  O OE2 . GLU C 1 299 ? 47.100  -10.748 -24.557 1.00 116.66 ? 299 GLU C OE2 1 
ATOM   9583  N N   . GLN C 1 300 ? 42.589  -8.236  -25.144 1.00 56.45  ? 300 GLN C N   1 
ATOM   9584  C CA  . GLN C 1 300 ? 41.189  -8.157  -25.522 1.00 57.94  ? 300 GLN C CA  1 
ATOM   9585  C C   . GLN C 1 300 ? 40.477  -7.106  -24.678 1.00 54.54  ? 300 GLN C C   1 
ATOM   9586  O O   . GLN C 1 300 ? 39.725  -6.307  -25.241 1.00 56.64  ? 300 GLN C O   1 
ATOM   9587  C CB  . GLN C 1 300 ? 40.493  -9.504  -25.368 1.00 58.25  ? 300 GLN C CB  1 
ATOM   9588  C CG  . GLN C 1 300 ? 41.088  -10.571 -26.264 1.00 56.59  ? 300 GLN C CG  1 
ATOM   9589  C CD  . GLN C 1 300 ? 40.389  -11.887 -26.085 1.00 54.13  ? 300 GLN C CD  1 
ATOM   9590  O OE1 . GLN C 1 300 ? 39.856  -12.203 -25.030 1.00 55.58  ? 300 GLN C OE1 1 
ATOM   9591  N NE2 . GLN C 1 300 ? 40.338  -12.650 -27.154 1.00 59.30  ? 300 GLN C NE2 1 
ATOM   9592  N N   . LEU C 1 301 ? 40.725  -7.107  -23.349 1.00 49.12  ? 301 LEU C N   1 
ATOM   9593  C CA  . LEU C 1 301 ? 39.927  -6.279  -22.450 1.00 46.98  ? 301 LEU C CA  1 
ATOM   9594  C C   . LEU C 1 301 ? 40.282  -4.817  -22.685 1.00 49.79  ? 301 LEU C C   1 
ATOM   9595  O O   . LEU C 1 301 ? 39.387  -3.973  -22.708 1.00 40.78  ? 301 LEU C O   1 
ATOM   9596  C CB  . LEU C 1 301 ? 40.121  -6.672  -20.979 1.00 45.32  ? 301 LEU C CB  1 
ATOM   9597  C CG  . LEU C 1 301 ? 39.336  -5.831  -19.959 1.00 48.42  ? 301 LEU C CG  1 
ATOM   9598  C CD1 . LEU C 1 301 ? 37.847  -5.855  -20.251 1.00 49.77  ? 301 LEU C CD1 1 
ATOM   9599  C CD2 . LEU C 1 301 ? 39.555  -6.323  -18.532 1.00 48.71  ? 301 LEU C CD2 1 
ATOM   9600  N N   . GLU C 1 302 ? 41.590  -4.560  -22.884 1.00 58.46  ? 302 GLU C N   1 
ATOM   9601  C CA  . GLU C 1 302 ? 42.121  -3.221  -23.080 1.00 54.38  ? 302 GLU C CA  1 
ATOM   9602  C C   . GLU C 1 302 ? 41.528  -2.616  -24.348 1.00 53.35  ? 302 GLU C C   1 
ATOM   9603  O O   . GLU C 1 302 ? 41.072  -1.477  -24.328 1.00 55.31  ? 302 GLU C O   1 
ATOM   9604  C CB  . GLU C 1 302 ? 43.650  -3.245  -23.125 1.00 58.50  ? 302 GLU C CB  1 
ATOM   9605  C CG  . GLU C 1 302 ? 44.261  -1.855  -23.276 1.00 74.61  ? 302 GLU C CG  1 
ATOM   9606  C CD  . GLU C 1 302 ? 45.666  -1.657  -22.713 1.00 87.91  ? 302 GLU C CD  1 
ATOM   9607  O OE1 . GLU C 1 302 ? 46.144  -0.490  -22.737 1.00 76.93  ? 302 GLU C OE1 1 
ATOM   9608  O OE2 . GLU C 1 302 ? 46.281  -2.658  -22.236 1.00 89.61  ? 302 GLU C OE2 1 
ATOM   9609  N N   . ARG C 1 303 ? 41.476  -3.403  -25.425 1.00 51.37  ? 303 ARG C N   1 
ATOM   9610  C CA  . ARG C 1 303 ? 40.960  -2.906  -26.694 1.00 56.63  ? 303 ARG C CA  1 
ATOM   9611  C C   . ARG C 1 303 ? 39.469  -2.591  -26.576 1.00 57.48  ? 303 ARG C C   1 
ATOM   9612  O O   . ARG C 1 303 ? 38.995  -1.591  -27.125 1.00 54.69  ? 303 ARG C O   1 
ATOM   9613  C CB  . ARG C 1 303 ? 41.227  -3.919  -27.812 1.00 55.61  ? 303 ARG C CB  1 
ATOM   9614  C CG  . ARG C 1 303 ? 40.324  -3.802  -29.038 1.00 55.83  ? 303 ARG C CG  1 
ATOM   9615  C CD  . ARG C 1 303 ? 40.698  -4.866  -30.055 1.00 64.69  ? 303 ARG C CD  1 
ATOM   9616  N NE  . ARG C 1 303 ? 41.925  -4.518  -30.775 1.00 75.59  ? 303 ARG C NE  1 
ATOM   9617  C CZ  . ARG C 1 303 ? 41.980  -3.647  -31.792 1.00 78.35  ? 303 ARG C CZ  1 
ATOM   9618  N NH1 . ARG C 1 303 ? 40.866  -3.110  -32.272 1.00 77.73  ? 303 ARG C NH1 1 
ATOM   9619  N NH2 . ARG C 1 303 ? 43.142  -3.334  -32.344 1.00 64.62  ? 303 ARG C NH2 1 
ATOM   9620  N N   . PHE C 1 304 ? 38.733  -3.470  -25.887 1.00 55.98  ? 304 PHE C N   1 
ATOM   9621  C CA  . PHE C 1 304 ? 37.297  -3.306  -25.712 1.00 51.03  ? 304 PHE C CA  1 
ATOM   9622  C C   . PHE C 1 304 ? 37.016  -2.059  -24.864 1.00 49.51  ? 304 PHE C C   1 
ATOM   9623  O O   . PHE C 1 304 ? 36.095  -1.302  -25.147 1.00 43.20  ? 304 PHE C O   1 
ATOM   9624  C CB  . PHE C 1 304 ? 36.704  -4.566  -25.070 1.00 53.25  ? 304 PHE C CB  1 
ATOM   9625  C CG  . PHE C 1 304 ? 35.234  -4.461  -24.770 1.00 55.18  ? 304 PHE C CG  1 
ATOM   9626  C CD1 . PHE C 1 304 ? 34.299  -4.718  -25.761 1.00 60.50  ? 304 PHE C CD1 1 
ATOM   9627  C CD2 . PHE C 1 304 ? 34.790  -3.988  -23.542 1.00 57.97  ? 304 PHE C CD2 1 
ATOM   9628  C CE1 . PHE C 1 304 ? 32.945  -4.563  -25.517 1.00 55.92  ? 304 PHE C CE1 1 
ATOM   9629  C CE2 . PHE C 1 304 ? 33.433  -3.834  -23.299 1.00 57.16  ? 304 PHE C CE2 1 
ATOM   9630  C CZ  . PHE C 1 304 ? 32.521  -4.128  -24.288 1.00 57.06  ? 304 PHE C CZ  1 
ATOM   9631  N N   . ALA C 1 305 ? 37.808  -1.841  -23.801 1.00 53.34  ? 305 ALA C N   1 
ATOM   9632  C CA  . ALA C 1 305 ? 37.628  -0.654  -22.980 1.00 56.50  ? 305 ALA C CA  1 
ATOM   9633  C C   . ALA C 1 305 ? 37.714  0.596   -23.860 1.00 56.47  ? 305 ALA C C   1 
ATOM   9634  O O   . ALA C 1 305 ? 36.890  1.501   -23.742 1.00 54.22  ? 305 ALA C O   1 
ATOM   9635  C CB  . ALA C 1 305 ? 38.652  -0.613  -21.871 1.00 51.24  ? 305 ALA C CB  1 
ATOM   9636  N N   . TRP C 1 306 ? 38.750  0.638   -24.712 1.00 58.59  ? 306 TRP C N   1 
ATOM   9637  C CA  . TRP C 1 306 ? 38.990  1.752   -25.616 1.00 57.76  ? 306 TRP C CA  1 
ATOM   9638  C C   . TRP C 1 306 ? 37.833  1.887   -26.600 1.00 53.93  ? 306 TRP C C   1 
ATOM   9639  O O   . TRP C 1 306 ? 37.350  2.987   -26.841 1.00 62.11  ? 306 TRP C O   1 
ATOM   9640  C CB  . TRP C 1 306 ? 40.345  1.610   -26.321 1.00 53.32  ? 306 TRP C CB  1 
ATOM   9641  C CG  . TRP C 1 306 ? 41.514  2.061   -25.502 1.00 48.23  ? 306 TRP C CG  1 
ATOM   9642  C CD1 . TRP C 1 306 ? 42.561  1.307   -25.061 1.00 55.18  ? 306 TRP C CD1 1 
ATOM   9643  C CD2 . TRP C 1 306 ? 41.764  3.394   -25.037 1.00 46.23  ? 306 TRP C CD2 1 
ATOM   9644  N NE1 . TRP C 1 306 ? 43.445  2.080   -24.353 1.00 54.43  ? 306 TRP C NE1 1 
ATOM   9645  C CE2 . TRP C 1 306 ? 42.972  3.363   -24.313 1.00 50.49  ? 306 TRP C CE2 1 
ATOM   9646  C CE3 . TRP C 1 306 ? 41.095  4.612   -25.181 1.00 54.89  ? 306 TRP C CE3 1 
ATOM   9647  C CZ2 . TRP C 1 306 ? 43.524  4.510   -23.741 1.00 59.43  ? 306 TRP C CZ2 1 
ATOM   9648  C CZ3 . TRP C 1 306 ? 41.633  5.745   -24.607 1.00 58.67  ? 306 TRP C CZ3 1 
ATOM   9649  C CH2 . TRP C 1 306 ? 42.828  5.691   -23.885 1.00 56.53  ? 306 TRP C CH2 1 
ATOM   9650  N N   . ASP C 1 307 ? 37.371  0.772   -27.150 1.00 50.64  ? 307 ASP C N   1 
ATOM   9651  C CA  . ASP C 1 307 ? 36.243  0.832   -28.069 1.00 64.80  ? 307 ASP C CA  1 
ATOM   9652  C C   . ASP C 1 307 ? 35.044  1.440   -27.347 1.00 59.27  ? 307 ASP C C   1 
ATOM   9653  O O   . ASP C 1 307 ? 34.365  2.292   -27.902 1.00 61.67  ? 307 ASP C O   1 
ATOM   9654  C CB  . ASP C 1 307 ? 35.907  -0.539  -28.676 1.00 70.79  ? 307 ASP C CB  1 
ATOM   9655  C CG  . ASP C 1 307 ? 37.002  -1.109  -29.572 1.00 78.20  ? 307 ASP C CG  1 
ATOM   9656  O OD1 . ASP C 1 307 ? 37.848  -0.309  -30.059 1.00 68.65  ? 307 ASP C OD1 1 
ATOM   9657  O OD2 . ASP C 1 307 ? 37.036  -2.355  -29.739 1.00 78.23  ? 307 ASP C OD2 1 
ATOM   9658  N N   . THR C 1 308 ? 34.815  1.014   -26.102 1.00 67.12  ? 308 THR C N   1 
ATOM   9659  C CA  . THR C 1 308 ? 33.697  1.474   -25.284 1.00 66.00  ? 308 THR C CA  1 
ATOM   9660  C C   . THR C 1 308 ? 33.775  2.993   -25.086 1.00 63.01  ? 308 THR C C   1 
ATOM   9661  O O   . THR C 1 308 ? 32.800  3.721   -25.271 1.00 62.14  ? 308 THR C O   1 
ATOM   9662  C CB  . THR C 1 308 ? 33.682  0.674   -23.971 1.00 67.00  ? 308 THR C CB  1 
ATOM   9663  O OG1 . THR C 1 308 ? 33.214  -0.639  -24.272 1.00 70.84  ? 308 THR C OG1 1 
ATOM   9664  C CG2 . THR C 1 308 ? 32.805  1.261   -22.893 1.00 80.83  ? 308 THR C CG2 1 
ATOM   9665  N N   . LEU C 1 309 ? 34.952  3.482   -24.701 1.00 55.03  ? 309 LEU C N   1 
ATOM   9666  C CA  . LEU C 1 309 ? 35.102  4.888   -24.378 1.00 58.62  ? 309 LEU C CA  1 
ATOM   9667  C C   . LEU C 1 309 ? 35.004  5.740   -25.651 1.00 65.36  ? 309 LEU C C   1 
ATOM   9668  O O   . LEU C 1 309 ? 34.410  6.818   -25.611 1.00 66.33  ? 309 LEU C O   1 
ATOM   9669  C CB  . LEU C 1 309 ? 36.446  5.076   -23.663 1.00 60.38  ? 309 LEU C CB  1 
ATOM   9670  C CG  . LEU C 1 309 ? 36.554  4.423   -22.288 1.00 59.79  ? 309 LEU C CG  1 
ATOM   9671  C CD1 . LEU C 1 309 ? 37.991  4.434   -21.806 1.00 63.14  ? 309 LEU C CD1 1 
ATOM   9672  C CD2 . LEU C 1 309 ? 35.657  5.127   -21.274 1.00 63.33  ? 309 LEU C CD2 1 
ATOM   9673  N N   . ASN C 1 310 ? 35.555  5.260   -26.783 1.00 60.90  ? 310 ASN C N   1 
ATOM   9674  C CA  . ASN C 1 310 ? 35.514  6.019   -28.026 1.00 59.93  ? 310 ASN C CA  1 
ATOM   9675  C C   . ASN C 1 310 ? 34.134  5.944   -28.673 1.00 61.79  ? 310 ASN C C   1 
ATOM   9676  O O   . ASN C 1 310 ? 33.878  6.655   -29.635 1.00 77.35  ? 310 ASN C O   1 
ATOM   9677  C CB  . ASN C 1 310 ? 36.600  5.601   -29.030 1.00 58.07  ? 310 ASN C CB  1 
ATOM   9678  C CG  . ASN C 1 310 ? 37.988  6.028   -28.587 1.00 58.05  ? 310 ASN C CG  1 
ATOM   9679  O OD1 . ASN C 1 310 ? 38.155  7.052   -27.930 1.00 56.36  ? 310 ASN C OD1 1 
ATOM   9680  N ND2 . ASN C 1 310 ? 38.988  5.221   -28.884 1.00 57.72  ? 310 ASN C ND2 1 
ATOM   9681  N N   . SER C 1 311 ? 33.227  5.100   -28.175 1.00 66.35  ? 311 SER C N   1 
ATOM   9682  C CA  . SER C 1 311 ? 31.845  5.210   -28.621 1.00 74.75  ? 311 SER C CA  1 
ATOM   9683  C C   . SER C 1 311 ? 31.027  5.975   -27.572 1.00 69.80  ? 311 SER C C   1 
ATOM   9684  O O   . SER C 1 311 ? 29.801  5.967   -27.608 1.00 71.21  ? 311 SER C O   1 
ATOM   9685  C CB  . SER C 1 311 ? 31.249  3.860   -29.011 1.00 77.20  ? 311 SER C CB  1 
ATOM   9686  O OG  . SER C 1 311 ? 31.301  2.934   -27.941 1.00 87.24  ? 311 SER C OG  1 
ATOM   9687  N N   . GLY C 1 312 ? 31.730  6.653   -26.648 1.00 76.25  ? 312 GLY C N   1 
ATOM   9688  C CA  . GLY C 1 312 ? 31.142  7.601   -25.712 1.00 75.12  ? 312 GLY C CA  1 
ATOM   9689  C C   . GLY C 1 312 ? 30.437  6.926   -24.536 1.00 77.92  ? 312 GLY C C   1 
ATOM   9690  O O   . GLY C 1 312 ? 29.591  7.548   -23.909 1.00 65.95  ? 312 GLY C O   1 
ATOM   9691  N N   . GLN C 1 313 ? 30.775  5.656   -24.257 1.00 77.33  ? 313 GLN C N   1 
ATOM   9692  C CA  . GLN C 1 313 ? 30.120  4.888   -23.208 1.00 69.23  ? 313 GLN C CA  1 
ATOM   9693  C C   . GLN C 1 313 ? 30.933  5.040   -21.928 1.00 57.80  ? 313 GLN C C   1 
ATOM   9694  O O   . GLN C 1 313 ? 32.122  5.326   -21.992 1.00 54.39  ? 313 GLN C O   1 
ATOM   9695  C CB  . GLN C 1 313 ? 30.007  3.412   -23.606 1.00 67.56  ? 313 GLN C CB  1 
ATOM   9696  C CG  . GLN C 1 313 ? 29.050  3.128   -24.753 1.00 73.74  ? 313 GLN C CG  1 
ATOM   9697  C CD  . GLN C 1 313 ? 27.645  2.940   -24.239 1.00 83.60  ? 313 GLN C CD  1 
ATOM   9698  O OE1 . GLN C 1 313 ? 27.186  1.824   -24.025 1.00 84.05  ? 313 GLN C OE1 1 
ATOM   9699  N NE2 . GLN C 1 313 ? 26.958  4.035   -23.974 1.00 81.88  ? 313 GLN C NE2 1 
ATOM   9700  N N   . VAL C 1 314 ? 30.293  4.820   -20.773 1.00 59.71  ? 314 VAL C N   1 
ATOM   9701  C CA  . VAL C 1 314 ? 31.026  4.724   -19.519 1.00 65.74  ? 314 VAL C CA  1 
ATOM   9702  C C   . VAL C 1 314 ? 31.398  3.260   -19.268 1.00 61.94  ? 314 VAL C C   1 
ATOM   9703  O O   . VAL C 1 314 ? 30.745  2.340   -19.762 1.00 60.83  ? 314 VAL C O   1 
ATOM   9704  C CB  . VAL C 1 314 ? 30.233  5.302   -18.325 1.00 72.57  ? 314 VAL C CB  1 
ATOM   9705  C CG1 . VAL C 1 314 ? 29.727  6.707   -18.621 1.00 76.78  ? 314 VAL C CG1 1 
ATOM   9706  C CG2 . VAL C 1 314 ? 29.079  4.404   -17.895 1.00 72.60  ? 314 VAL C CG2 1 
ATOM   9707  N N   . ILE C 1 315 ? 32.474  3.068   -18.505 1.00 54.85  ? 315 ILE C N   1 
ATOM   9708  C CA  . ILE C 1 315 ? 32.822  1.777   -17.951 1.00 56.51  ? 315 ILE C CA  1 
ATOM   9709  C C   . ILE C 1 315 ? 32.190  1.701   -16.569 1.00 54.57  ? 315 ILE C C   1 
ATOM   9710  O O   . ILE C 1 315 ? 32.540  2.469   -15.688 1.00 49.92  ? 315 ILE C O   1 
ATOM   9711  C CB  . ILE C 1 315 ? 34.351  1.594   -17.889 1.00 61.39  ? 315 ILE C CB  1 
ATOM   9712  C CG1 . ILE C 1 315 ? 34.928  1.394   -19.293 1.00 61.53  ? 315 ILE C CG1 1 
ATOM   9713  C CG2 . ILE C 1 315 ? 34.735  0.447   -16.962 1.00 53.53  ? 315 ILE C CG2 1 
ATOM   9714  C CD1 . ILE C 1 315 ? 36.371  1.714   -19.372 1.00 61.18  ? 315 ILE C CD1 1 
ATOM   9715  N N   . PRO C 1 316 ? 31.253  0.773   -16.316 1.00 51.93  ? 316 PRO C N   1 
ATOM   9716  C CA  . PRO C 1 316 ? 30.592  0.724   -15.015 1.00 52.04  ? 316 PRO C CA  1 
ATOM   9717  C C   . PRO C 1 316 ? 31.575  0.381   -13.897 1.00 42.26  ? 316 PRO C C   1 
ATOM   9718  O O   . PRO C 1 316 ? 32.498  -0.387  -14.100 1.00 41.37  ? 316 PRO C O   1 
ATOM   9719  C CB  . PRO C 1 316 ? 29.539  -0.380  -15.195 1.00 53.42  ? 316 PRO C CB  1 
ATOM   9720  C CG  . PRO C 1 316 ? 29.362  -0.462  -16.678 1.00 52.65  ? 316 PRO C CG  1 
ATOM   9721  C CD  . PRO C 1 316 ? 30.756  -0.246  -17.243 1.00 48.24  ? 316 PRO C CD  1 
ATOM   9722  N N   . GLY C 1 317 ? 31.383  1.028   -12.744 1.00 42.72  ? 317 GLY C N   1 
ATOM   9723  C CA  . GLY C 1 317 ? 31.942  0.588   -11.488 1.00 40.86  ? 317 GLY C CA  1 
ATOM   9724  C C   . GLY C 1 317 ? 33.238  1.310   -11.200 1.00 40.76  ? 317 GLY C C   1 
ATOM   9725  O O   . GLY C 1 317 ? 33.928  0.980   -10.253 1.00 35.89  ? 317 GLY C O   1 
ATOM   9726  N N   . TYR C 1 318 ? 33.576  2.250   -12.079 1.00 44.50  ? 318 TYR C N   1 
ATOM   9727  C CA  . TYR C 1 318 ? 34.792  3.022   -11.934 1.00 47.64  ? 318 TYR C CA  1 
ATOM   9728  C C   . TYR C 1 318 ? 34.353  4.477   -11.823 1.00 47.77  ? 318 TYR C C   1 
ATOM   9729  O O   . TYR C 1 318 ? 33.331  4.871   -12.394 1.00 49.54  ? 318 TYR C O   1 
ATOM   9730  C CB  . TYR C 1 318 ? 35.786  2.712   -13.075 1.00 47.33  ? 318 TYR C CB  1 
ATOM   9731  C CG  . TYR C 1 318 ? 36.461  1.383   -12.887 1.00 46.19  ? 318 TYR C CG  1 
ATOM   9732  C CD1 . TYR C 1 318 ? 35.787  0.191   -13.117 1.00 45.60  ? 318 TYR C CD1 1 
ATOM   9733  C CD2 . TYR C 1 318 ? 37.745  1.319   -12.388 1.00 44.91  ? 318 TYR C CD2 1 
ATOM   9734  C CE1 . TYR C 1 318 ? 36.376  -1.038  -12.853 1.00 42.87  ? 318 TYR C CE1 1 
ATOM   9735  C CE2 . TYR C 1 318 ? 38.351  0.097   -12.141 1.00 46.71  ? 318 TYR C CE2 1 
ATOM   9736  C CZ  . TYR C 1 318 ? 37.672  -1.079  -12.386 1.00 37.12  ? 318 TYR C CZ  1 
ATOM   9737  O OH  . TYR C 1 318 ? 38.280  -2.247  -12.057 1.00 35.28  ? 318 TYR C OH  1 
ATOM   9738  N N   . GLY C 1 319 ? 35.140  5.259   -11.083 1.00 49.22  ? 319 GLY C N   1 
ATOM   9739  C CA  . GLY C 1 319 ? 34.859  6.674   -10.914 1.00 48.87  ? 319 GLY C CA  1 
ATOM   9740  C C   . GLY C 1 319 ? 34.008  6.893   -9.677  1.00 44.32  ? 319 GLY C C   1 
ATOM   9741  O O   . GLY C 1 319 ? 33.489  5.934   -9.112  1.00 48.44  ? 319 GLY C O   1 
ATOM   9742  N N   . HIS C 1 320 ? 33.956  8.144   -9.228  1.00 52.44  ? 320 HIS C N   1 
ATOM   9743  C CA  . HIS C 1 320 ? 33.169  8.507   -8.061  1.00 57.78  ? 320 HIS C CA  1 
ATOM   9744  C C   . HIS C 1 320 ? 33.076  10.023  -7.980  1.00 51.14  ? 320 HIS C C   1 
ATOM   9745  O O   . HIS C 1 320 ? 33.975  10.711  -8.443  1.00 55.98  ? 320 HIS C O   1 
ATOM   9746  C CB  . HIS C 1 320 ? 33.804  7.942   -6.786  1.00 57.51  ? 320 HIS C CB  1 
ATOM   9747  C CG  . HIS C 1 320 ? 32.850  7.879   -5.652  1.00 61.50  ? 320 HIS C CG  1 
ATOM   9748  N ND1 . HIS C 1 320 ? 32.774  8.865   -4.688  1.00 63.01  ? 320 HIS C ND1 1 
ATOM   9749  C CD2 . HIS C 1 320 ? 31.908  6.970   -5.349  1.00 61.90  ? 320 HIS C CD2 1 
ATOM   9750  C CE1 . HIS C 1 320 ? 31.815  8.544   -3.823  1.00 60.93  ? 320 HIS C CE1 1 
ATOM   9751  N NE2 . HIS C 1 320 ? 31.289  7.391   -4.196  1.00 60.06  ? 320 HIS C NE2 1 
ATOM   9752  N N   . ALA C 1 321 ? 32.033  10.521  -7.319  1.00 54.65  ? 321 ALA C N   1 
ATOM   9753  C CA  . ALA C 1 321 ? 31.877  11.954  -7.099  1.00 63.15  ? 321 ALA C CA  1 
ATOM   9754  C C   . ALA C 1 321 ? 33.003  12.505  -6.220  1.00 65.15  ? 321 ALA C C   1 
ATOM   9755  O O   . ALA C 1 321 ? 33.453  13.619  -6.464  1.00 72.93  ? 321 ALA C O   1 
ATOM   9756  C CB  . ALA C 1 321 ? 30.509  12.278  -6.525  1.00 58.01  ? 321 ALA C CB  1 
ATOM   9757  N N   . VAL C 1 322 ? 33.490  11.735  -5.231  1.00 66.98  ? 322 VAL C N   1 
ATOM   9758  C CA  . VAL C 1 322 ? 34.382  12.311  -4.234  1.00 67.90  ? 322 VAL C CA  1 
ATOM   9759  C C   . VAL C 1 322 ? 35.622  11.443  -4.008  1.00 63.32  ? 322 VAL C C   1 
ATOM   9760  O O   . VAL C 1 322 ? 36.697  12.013  -3.824  1.00 66.85  ? 322 VAL C O   1 
ATOM   9761  C CB  . VAL C 1 322 ? 33.626  12.640  -2.924  1.00 78.83  ? 322 VAL C CB  1 
ATOM   9762  C CG1 . VAL C 1 322 ? 32.763  11.490  -2.444  1.00 82.53  ? 322 VAL C CG1 1 
ATOM   9763  C CG2 . VAL C 1 322 ? 34.560  13.091  -1.806  1.00 83.12  ? 322 VAL C CG2 1 
ATOM   9764  N N   . LEU C 1 323 ? 35.491  10.102  -4.002  1.00 62.57  ? 323 LEU C N   1 
ATOM   9765  C CA  . LEU C 1 323 ? 36.647  9.206   -3.932  1.00 61.98  ? 323 LEU C CA  1 
ATOM   9766  C C   . LEU C 1 323 ? 37.669  9.589   -5.013  1.00 62.73  ? 323 LEU C C   1 
ATOM   9767  O O   . LEU C 1 323 ? 37.280  9.925   -6.132  1.00 56.43  ? 323 LEU C O   1 
ATOM   9768  C CB  . LEU C 1 323 ? 36.228  7.739   -4.148  1.00 71.48  ? 323 LEU C CB  1 
ATOM   9769  C CG  . LEU C 1 323 ? 35.900  6.837   -2.948  1.00 77.41  ? 323 LEU C CG  1 
ATOM   9770  C CD1 . LEU C 1 323 ? 36.785  7.126   -1.758  1.00 72.13  ? 323 LEU C CD1 1 
ATOM   9771  C CD2 . LEU C 1 323 ? 34.434  6.918   -2.547  1.00 79.22  ? 323 LEU C CD2 1 
ATOM   9772  N N   . ARG C 1 324 ? 38.971  9.497   -4.683  1.00 59.24  ? 324 ARG C N   1 
ATOM   9773  C CA  . ARG C 1 324 ? 40.037  9.615   -5.667  1.00 60.12  ? 324 ARG C CA  1 
ATOM   9774  C C   . ARG C 1 324 ? 41.087  8.512   -5.481  1.00 57.53  ? 324 ARG C C   1 
ATOM   9775  O O   . ARG C 1 324 ? 42.181  8.592   -6.028  1.00 64.53  ? 324 ARG C O   1 
ATOM   9776  C CB  . ARG C 1 324 ? 40.679  11.013  -5.586  1.00 65.46  ? 324 ARG C CB  1 
ATOM   9777  C CG  . ARG C 1 324 ? 39.728  12.200  -5.770  1.00 61.33  ? 324 ARG C CG  1 
ATOM   9778  C CD  . ARG C 1 324 ? 39.228  12.393  -7.189  1.00 66.62  ? 324 ARG C CD  1 
ATOM   9779  N NE  . ARG C 1 324 ? 38.216  13.448  -7.335  1.00 61.19  ? 324 ARG C NE  1 
ATOM   9780  C CZ  . ARG C 1 324 ? 36.933  13.248  -7.621  1.00 69.58  ? 324 ARG C CZ  1 
ATOM   9781  N NH1 . ARG C 1 324 ? 36.420  12.027  -7.659  1.00 68.98  ? 324 ARG C NH1 1 
ATOM   9782  N NH2 . ARG C 1 324 ? 36.144  14.290  -7.827  1.00 74.02  ? 324 ARG C NH2 1 
ATOM   9783  N N   . VAL C 1 325 ? 40.778  7.469   -4.711  1.00 61.78  ? 325 VAL C N   1 
ATOM   9784  C CA  . VAL C 1 325 ? 41.587  6.250   -4.684  1.00 57.91  ? 325 VAL C CA  1 
ATOM   9785  C C   . VAL C 1 325 ? 40.650  5.053   -4.832  1.00 54.09  ? 325 VAL C C   1 
ATOM   9786  O O   . VAL C 1 325 ? 39.431  5.211   -4.924  1.00 60.51  ? 325 VAL C O   1 
ATOM   9787  C CB  . VAL C 1 325 ? 42.422  6.103   -3.396  1.00 56.04  ? 325 VAL C CB  1 
ATOM   9788  C CG1 . VAL C 1 325 ? 43.586  7.075   -3.366  1.00 58.88  ? 325 VAL C CG1 1 
ATOM   9789  C CG2 . VAL C 1 325 ? 41.550  6.221   -2.146  1.00 53.14  ? 325 VAL C CG2 1 
ATOM   9790  N N   . THR C 1 326 ? 41.226  3.850   -4.829  1.00 52.14  ? 326 THR C N   1 
ATOM   9791  C CA  . THR C 1 326 ? 40.422  2.646   -4.815  1.00 47.86  ? 326 THR C CA  1 
ATOM   9792  C C   . THR C 1 326 ? 39.606  2.583   -3.521  1.00 48.90  ? 326 THR C C   1 
ATOM   9793  O O   . THR C 1 326 ? 40.113  2.866   -2.435  1.00 43.25  ? 326 THR C O   1 
ATOM   9794  C CB  . THR C 1 326 ? 41.314  1.426   -5.014  1.00 53.12  ? 326 THR C CB  1 
ATOM   9795  O OG1 . THR C 1 326 ? 41.920  1.572   -6.310  1.00 55.72  ? 326 THR C OG1 1 
ATOM   9796  C CG2 . THR C 1 326 ? 40.532  0.139   -4.857  1.00 47.58  ? 326 THR C CG2 1 
ATOM   9797  N N   . ASP C 1 327 ? 38.336  2.189   -3.669  1.00 47.38  ? 327 ASP C N   1 
ATOM   9798  C CA  . ASP C 1 327 ? 37.351  2.226   -2.602  1.00 41.41  ? 327 ASP C CA  1 
ATOM   9799  C C   . ASP C 1 327 ? 37.661  1.098   -1.628  1.00 38.62  ? 327 ASP C C   1 
ATOM   9800  O O   . ASP C 1 327 ? 37.750  -0.079  -2.017  1.00 35.43  ? 327 ASP C O   1 
ATOM   9801  C CB  . ASP C 1 327 ? 35.943  2.164   -3.209  1.00 44.53  ? 327 ASP C CB  1 
ATOM   9802  C CG  . ASP C 1 327 ? 34.788  2.321   -2.228  1.00 44.42  ? 327 ASP C CG  1 
ATOM   9803  O OD1 . ASP C 1 327 ? 35.019  2.177   -0.998  1.00 44.18  ? 327 ASP C OD1 1 
ATOM   9804  O OD2 . ASP C 1 327 ? 33.655  2.582   -2.701  1.00 45.58  ? 327 ASP C OD2 1 
ATOM   9805  N N   . PRO C 1 328 ? 37.844  1.406   -0.321  1.00 35.12  ? 328 PRO C N   1 
ATOM   9806  C CA  . PRO C 1 328 ? 38.101  0.355   0.663   1.00 42.88  ? 328 PRO C CA  1 
ATOM   9807  C C   . PRO C 1 328 ? 36.998  -0.698  0.758   1.00 41.30  ? 328 PRO C C   1 
ATOM   9808  O O   . PRO C 1 328 ? 37.263  -1.825  1.190   1.00 45.63  ? 328 PRO C O   1 
ATOM   9809  C CB  . PRO C 1 328 ? 38.338  1.072   2.000   1.00 40.57  ? 328 PRO C CB  1 
ATOM   9810  C CG  . PRO C 1 328 ? 37.952  2.498   1.761   1.00 42.60  ? 328 PRO C CG  1 
ATOM   9811  C CD  . PRO C 1 328 ? 37.892  2.741   0.266   1.00 38.12  ? 328 PRO C CD  1 
ATOM   9812  N N   . ARG C 1 329 ? 35.790  -0.338  0.305   1.00 39.10  ? 329 ARG C N   1 
ATOM   9813  C CA  . ARG C 1 329 ? 34.681  -1.269  0.251   1.00 37.24  ? 329 ARG C CA  1 
ATOM   9814  C C   . ARG C 1 329 ? 34.827  -2.228  -0.930  1.00 38.40  ? 329 ARG C C   1 
ATOM   9815  O O   . ARG C 1 329 ? 34.374  -3.375  -0.850  1.00 36.27  ? 329 ARG C O   1 
ATOM   9816  C CB  . ARG C 1 329 ? 33.366  -0.503  0.153   1.00 39.05  ? 329 ARG C CB  1 
ATOM   9817  C CG  . ARG C 1 329 ? 33.142  0.473   1.295   1.00 36.80  ? 329 ARG C CG  1 
ATOM   9818  C CD  . ARG C 1 329 ? 31.908  1.313   1.093   1.00 34.24  ? 329 ARG C CD  1 
ATOM   9819  N NE  . ARG C 1 329 ? 32.031  2.206   -0.030  1.00 32.91  ? 329 ARG C NE  1 
ATOM   9820  C CZ  . ARG C 1 329 ? 31.019  2.830   -0.602  1.00 39.66  ? 329 ARG C CZ  1 
ATOM   9821  N NH1 . ARG C 1 329 ? 29.812  2.810   -0.048  1.00 41.34  ? 329 ARG C NH1 1 
ATOM   9822  N NH2 . ARG C 1 329 ? 31.238  3.536   -1.691  1.00 41.68  ? 329 ARG C NH2 1 
ATOM   9823  N N   . TYR C 1 330 ? 35.421  -1.759  -2.034  1.00 40.91  ? 330 TYR C N   1 
ATOM   9824  C CA  . TYR C 1 330 ? 35.830  -2.665  -3.111  1.00 39.30  ? 330 TYR C CA  1 
ATOM   9825  C C   . TYR C 1 330 ? 36.875  -3.656  -2.598  1.00 36.14  ? 330 TYR C C   1 
ATOM   9826  O O   . TYR C 1 330 ? 36.778  -4.862  -2.830  1.00 35.95  ? 330 TYR C O   1 
ATOM   9827  C CB  . TYR C 1 330 ? 36.340  -1.871  -4.322  1.00 41.16  ? 330 TYR C CB  1 
ATOM   9828  C CG  . TYR C 1 330 ? 36.839  -2.700  -5.479  1.00 41.77  ? 330 TYR C CG  1 
ATOM   9829  C CD1 . TYR C 1 330 ? 38.153  -3.154  -5.526  1.00 47.02  ? 330 TYR C CD1 1 
ATOM   9830  C CD2 . TYR C 1 330 ? 36.017  -2.995  -6.549  1.00 38.90  ? 330 TYR C CD2 1 
ATOM   9831  C CE1 . TYR C 1 330 ? 38.623  -3.906  -6.592  1.00 44.92  ? 330 TYR C CE1 1 
ATOM   9832  C CE2 . TYR C 1 330 ? 36.450  -3.780  -7.603  1.00 40.49  ? 330 TYR C CE2 1 
ATOM   9833  C CZ  . TYR C 1 330 ? 37.764  -4.225  -7.629  1.00 43.34  ? 330 TYR C CZ  1 
ATOM   9834  O OH  . TYR C 1 330 ? 38.207  -4.996  -8.661  1.00 41.25  ? 330 TYR C OH  1 
ATOM   9835  N N   . VAL C 1 331 ? 37.871  -3.135  -1.885  1.00 39.28  ? 331 VAL C N   1 
ATOM   9836  C CA  . VAL C 1 331 ? 38.995  -3.934  -1.411  1.00 42.00  ? 331 VAL C CA  1 
ATOM   9837  C C   . VAL C 1 331 ? 38.474  -5.066  -0.528  1.00 39.77  ? 331 VAL C C   1 
ATOM   9838  O O   . VAL C 1 331 ? 38.845  -6.221  -0.748  1.00 35.78  ? 331 VAL C O   1 
ATOM   9839  C CB  . VAL C 1 331 ? 40.043  -3.056  -0.681  1.00 49.96  ? 331 VAL C CB  1 
ATOM   9840  C CG1 . VAL C 1 331 ? 41.134  -3.861  0.025   1.00 48.81  ? 331 VAL C CG1 1 
ATOM   9841  C CG2 . VAL C 1 331 ? 40.681  -2.045  -1.628  1.00 49.28  ? 331 VAL C CG2 1 
ATOM   9842  N N   . ALA C 1 332 ? 37.590  -4.743  0.438   1.00 38.22  ? 332 ALA C N   1 
ATOM   9843  C CA  . ALA C 1 332 ? 37.066  -5.758  1.342   1.00 33.68  ? 332 ALA C CA  1 
ATOM   9844  C C   . ALA C 1 332 ? 36.334  -6.847  0.579   1.00 35.96  ? 332 ALA C C   1 
ATOM   9845  O O   . ALA C 1 332 ? 36.362  -8.008  0.972   1.00 39.11  ? 332 ALA C O   1 
ATOM   9846  C CB  . ALA C 1 332 ? 36.153  -5.143  2.362   1.00 36.72  ? 332 ALA C CB  1 
ATOM   9847  N N   . GLN C 1 333 ? 35.613  -6.460  -0.480  1.00 40.52  ? 333 GLN C N   1 
ATOM   9848  C CA  . GLN C 1 333 ? 34.870  -7.423  -1.274  1.00 40.20  ? 333 GLN C CA  1 
ATOM   9849  C C   . GLN C 1 333 ? 35.839  -8.294  -2.069  1.00 43.97  ? 333 GLN C C   1 
ATOM   9850  O O   . GLN C 1 333 ? 35.606  -9.497  -2.238  1.00 41.73  ? 333 GLN C O   1 
ATOM   9851  C CB  . GLN C 1 333 ? 33.891  -6.687  -2.186  1.00 41.41  ? 333 GLN C CB  1 
ATOM   9852  C CG  . GLN C 1 333 ? 32.722  -6.098  -1.415  1.00 43.73  ? 333 GLN C CG  1 
ATOM   9853  C CD  . GLN C 1 333 ? 31.706  -5.446  -2.305  1.00 42.55  ? 333 GLN C CD  1 
ATOM   9854  O OE1 . GLN C 1 333 ? 30.618  -5.978  -2.505  1.00 43.70  ? 333 GLN C OE1 1 
ATOM   9855  N NE2 . GLN C 1 333 ? 32.055  -4.276  -2.829  1.00 47.16  ? 333 GLN C NE2 1 
ATOM   9856  N N   . ARG C 1 334 ? 36.917  -7.681  -2.575  1.00 41.93  ? 334 ARG C N   1 
ATOM   9857  C CA  . ARG C 1 334 ? 37.942  -8.448  -3.264  1.00 41.23  ? 334 ARG C CA  1 
ATOM   9858  C C   . ARG C 1 334 ? 38.527  -9.475  -2.307  1.00 37.77  ? 334 ARG C C   1 
ATOM   9859  O O   . ARG C 1 334 ? 38.618  -10.673 -2.613  1.00 44.39  ? 334 ARG C O   1 
ATOM   9860  C CB  . ARG C 1 334 ? 39.018  -7.528  -3.836  1.00 42.28  ? 334 ARG C CB  1 
ATOM   9861  C CG  . ARG C 1 334 ? 40.143  -8.242  -4.574  1.00 44.64  ? 334 ARG C CG  1 
ATOM   9862  C CD  . ARG C 1 334 ? 41.117  -7.194  -5.055  1.00 44.22  ? 334 ARG C CD  1 
ATOM   9863  N NE  . ARG C 1 334 ? 42.316  -7.753  -5.628  1.00 46.15  ? 334 ARG C NE  1 
ATOM   9864  C CZ  . ARG C 1 334 ? 42.390  -8.536  -6.699  1.00 50.98  ? 334 ARG C CZ  1 
ATOM   9865  N NH1 . ARG C 1 334 ? 41.355  -8.772  -7.496  1.00 47.47  ? 334 ARG C NH1 1 
ATOM   9866  N NH2 . ARG C 1 334 ? 43.553  -9.096  -6.963  1.00 45.57  ? 334 ARG C NH2 1 
ATOM   9867  N N   . ASP C 1 335 ? 38.809  -9.035  -1.091  1.00 37.24  ? 335 ASP C N   1 
ATOM   9868  C CA  . ASP C 1 335 ? 39.355  -9.963  -0.117  1.00 37.76  ? 335 ASP C CA  1 
ATOM   9869  C C   . ASP C 1 335 ? 38.442  -11.161 0.060   1.00 36.49  ? 335 ASP C C   1 
ATOM   9870  O O   . ASP C 1 335 ? 38.906  -12.289 0.161   1.00 42.58  ? 335 ASP C O   1 
ATOM   9871  C CB  . ASP C 1 335 ? 39.641  -9.307  1.234   1.00 44.28  ? 335 ASP C CB  1 
ATOM   9872  C CG  . ASP C 1 335 ? 40.277  -10.320 2.180   1.00 55.11  ? 335 ASP C CG  1 
ATOM   9873  O OD1 . ASP C 1 335 ? 41.311  -10.952 1.790   1.00 53.36  ? 335 ASP C OD1 1 
ATOM   9874  O OD2 . ASP C 1 335 ? 39.694  -10.537 3.266   1.00 59.70  ? 335 ASP C OD2 1 
ATOM   9875  N N   . PHE C 1 336 ? 37.127  -10.928 0.139   1.00 43.05  ? 336 PHE C N   1 
ATOM   9876  C CA  . PHE C 1 336 ? 36.183  -12.007 0.388   1.00 39.29  ? 336 PHE C CA  1 
ATOM   9877  C C   . PHE C 1 336 ? 36.142  -12.954 -0.815  1.00 39.52  ? 336 PHE C C   1 
ATOM   9878  O O   . PHE C 1 336 ? 36.072  -14.160 -0.644  1.00 37.72  ? 336 PHE C O   1 
ATOM   9879  C CB  . PHE C 1 336 ? 34.821  -11.401 0.724   1.00 44.99  ? 336 PHE C CB  1 
ATOM   9880  C CG  . PHE C 1 336 ? 33.736  -12.382 1.049   1.00 41.72  ? 336 PHE C CG  1 
ATOM   9881  C CD1 . PHE C 1 336 ? 33.069  -13.055 0.027   1.00 40.23  ? 336 PHE C CD1 1 
ATOM   9882  C CD2 . PHE C 1 336 ? 33.381  -12.615 2.371   1.00 42.20  ? 336 PHE C CD2 1 
ATOM   9883  C CE1 . PHE C 1 336 ? 32.056  -13.949 0.321   1.00 40.17  ? 336 PHE C CE1 1 
ATOM   9884  C CE2 . PHE C 1 336 ? 32.368  -13.526 2.670   1.00 45.48  ? 336 PHE C CE2 1 
ATOM   9885  C CZ  . PHE C 1 336 ? 31.722  -14.198 1.643   1.00 46.23  ? 336 PHE C CZ  1 
ATOM   9886  N N   . ALA C 1 337 ? 36.210  -12.394 -2.024  1.00 39.57  ? 337 ALA C N   1 
ATOM   9887  C CA  . ALA C 1 337 ? 36.212  -13.157 -3.260  1.00 38.17  ? 337 ALA C CA  1 
ATOM   9888  C C   . ALA C 1 337 ? 37.447  -14.057 -3.342  1.00 40.89  ? 337 ALA C C   1 
ATOM   9889  O O   . ALA C 1 337 ? 37.327  -15.255 -3.639  1.00 40.26  ? 337 ALA C O   1 
ATOM   9890  C CB  . ALA C 1 337 ? 36.135  -12.199 -4.438  1.00 37.07  ? 337 ALA C CB  1 
ATOM   9891  N N   . LEU C 1 338 ? 38.630  -13.480 -3.070  1.00 45.83  ? 338 LEU C N   1 
ATOM   9892  C CA  . LEU C 1 338 ? 39.863  -14.257 -3.077  1.00 48.52  ? 338 LEU C CA  1 
ATOM   9893  C C   . LEU C 1 338 ? 39.780  -15.423 -2.089  1.00 49.02  ? 338 LEU C C   1 
ATOM   9894  O O   . LEU C 1 338 ? 40.131  -16.535 -2.441  1.00 57.93  ? 338 LEU C O   1 
ATOM   9895  C CB  . LEU C 1 338 ? 41.042  -13.345 -2.733  1.00 44.41  ? 338 LEU C CB  1 
ATOM   9896  C CG  . LEU C 1 338 ? 41.481  -12.380 -3.820  1.00 43.54  ? 338 LEU C CG  1 
ATOM   9897  C CD1 . LEU C 1 338 ? 42.551  -11.443 -3.295  1.00 40.84  ? 338 LEU C CD1 1 
ATOM   9898  C CD2 . LEU C 1 338 ? 41.984  -13.133 -5.045  1.00 46.24  ? 338 LEU C CD2 1 
ATOM   9899  N N   . LYS C 1 339 ? 39.276  -15.192 -0.873  1.00 51.08  ? 339 LYS C N   1 
ATOM   9900  C CA  . LYS C 1 339 ? 39.158  -16.256 0.119   1.00 53.55  ? 339 LYS C CA  1 
ATOM   9901  C C   . LYS C 1 339 ? 38.109  -17.293 -0.297  1.00 51.42  ? 339 LYS C C   1 
ATOM   9902  O O   . LYS C 1 339 ? 38.379  -18.478 -0.224  1.00 62.71  ? 339 LYS C O   1 
ATOM   9903  C CB  . LYS C 1 339 ? 38.880  -15.628 1.490   1.00 67.37  ? 339 LYS C CB  1 
ATOM   9904  C CG  . LYS C 1 339 ? 38.607  -16.594 2.642   1.00 89.21  ? 339 LYS C CG  1 
ATOM   9905  C CD  . LYS C 1 339 ? 38.370  -15.876 3.991   1.00 100.70 ? 339 LYS C CD  1 
ATOM   9906  C CE  . LYS C 1 339 ? 38.033  -16.785 5.164   1.00 94.00  ? 339 LYS C CE  1 
ATOM   9907  N NZ  . LYS C 1 339 ? 37.799  -16.014 6.413   1.00 80.15  ? 339 LYS C NZ  1 
ATOM   9908  N N   . HIS C 1 340 ? 36.923  -16.882 -0.778  1.00 54.08  ? 340 HIS C N   1 
ATOM   9909  C CA  . HIS C 1 340 ? 35.782  -17.793 -0.850  1.00 46.18  ? 340 HIS C CA  1 
ATOM   9910  C C   . HIS C 1 340 ? 35.388  -18.222 -2.268  1.00 49.82  ? 340 HIS C C   1 
ATOM   9911  O O   . HIS C 1 340 ? 34.795  -19.275 -2.406  1.00 42.06  ? 340 HIS C O   1 
ATOM   9912  C CB  . HIS C 1 340 ? 34.551  -17.219 -0.155  1.00 45.38  ? 340 HIS C CB  1 
ATOM   9913  C CG  . HIS C 1 340 ? 34.723  -16.984 1.294   1.00 44.85  ? 340 HIS C CG  1 
ATOM   9914  N ND1 . HIS C 1 340 ? 34.956  -17.994 2.195   1.00 58.72  ? 340 HIS C ND1 1 
ATOM   9915  C CD2 . HIS C 1 340 ? 34.721  -15.844 2.000   1.00 55.30  ? 340 HIS C CD2 1 
ATOM   9916  C CE1 . HIS C 1 340 ? 35.068  -17.476 3.421   1.00 64.46  ? 340 HIS C CE1 1 
ATOM   9917  N NE2 . HIS C 1 340 ? 34.945  -16.160 3.328   1.00 59.80  ? 340 HIS C NE2 1 
ATOM   9918  N N   . LEU C 1 341 ? 35.712  -17.465 -3.327  1.00 49.27  ? 341 LEU C N   1 
ATOM   9919  C CA  . LEU C 1 341 ? 35.360  -17.923 -4.671  1.00 50.45  ? 341 LEU C CA  1 
ATOM   9920  C C   . LEU C 1 341 ? 36.438  -17.518 -5.688  1.00 50.19  ? 341 LEU C C   1 
ATOM   9921  O O   . LEU C 1 341 ? 36.141  -16.922 -6.713  1.00 50.27  ? 341 LEU C O   1 
ATOM   9922  C CB  . LEU C 1 341 ? 33.965  -17.373 -5.013  1.00 48.75  ? 341 LEU C CB  1 
ATOM   9923  C CG  . LEU C 1 341 ? 33.763  -15.857 -4.830  1.00 42.47  ? 341 LEU C CG  1 
ATOM   9924  C CD1 . LEU C 1 341 ? 33.326  -15.184 -6.127  1.00 39.02  ? 341 LEU C CD1 1 
ATOM   9925  C CD2 . LEU C 1 341 ? 32.781  -15.556 -3.725  1.00 43.14  ? 341 LEU C CD2 1 
ATOM   9926  N N   . PRO C 1 342 ? 37.734  -17.873 -5.486  1.00 51.72  ? 342 PRO C N   1 
ATOM   9927  C CA  . PRO C 1 342 ? 38.792  -17.419 -6.398  1.00 48.13  ? 342 PRO C CA  1 
ATOM   9928  C C   . PRO C 1 342 ? 38.671  -17.990 -7.809  1.00 48.17  ? 342 PRO C C   1 
ATOM   9929  O O   . PRO C 1 342 ? 39.220  -17.406 -8.741  1.00 49.78  ? 342 PRO C O   1 
ATOM   9930  C CB  . PRO C 1 342 ? 40.115  -17.838 -5.741  1.00 46.34  ? 342 PRO C CB  1 
ATOM   9931  C CG  . PRO C 1 342 ? 39.718  -18.901 -4.694  1.00 48.21  ? 342 PRO C CG  1 
ATOM   9932  C CD  . PRO C 1 342 ? 38.246  -18.701 -4.378  1.00 47.56  ? 342 PRO C CD  1 
ATOM   9933  N N   . ASP C 1 343 ? 37.891  -19.064 -7.972  1.00 57.46  ? 343 ASP C N   1 
ATOM   9934  C CA  . ASP C 1 343 ? 37.789  -19.763 -9.256  1.00 63.10  ? 343 ASP C CA  1 
ATOM   9935  C C   . ASP C 1 343 ? 36.581  -19.307 -10.092 1.00 64.91  ? 343 ASP C C   1 
ATOM   9936  O O   . ASP C 1 343 ? 36.379  -19.800 -11.206 1.00 53.36  ? 343 ASP C O   1 
ATOM   9937  C CB  . ASP C 1 343 ? 37.782  -21.285 -9.038  1.00 63.21  ? 343 ASP C CB  1 
ATOM   9938  C CG  . ASP C 1 343 ? 39.148  -21.864 -8.651  1.00 69.59  ? 343 ASP C CG  1 
ATOM   9939  O OD1 . ASP C 1 343 ? 40.168  -21.417 -9.226  1.00 62.03  ? 343 ASP C OD1 1 
ATOM   9940  O OD2 . ASP C 1 343 ? 39.192  -22.774 -7.789  1.00 72.01  ? 343 ASP C OD2 1 
ATOM   9941  N N   . ASP C 1 344 ? 35.796  -18.340 -9.587  1.00 56.30  ? 344 ASP C N   1 
ATOM   9942  C CA  . ASP C 1 344 ? 34.592  -17.891 -10.274 1.00 50.99  ? 344 ASP C CA  1 
ATOM   9943  C C   . ASP C 1 344 ? 34.982  -17.056 -11.506 1.00 44.19  ? 344 ASP C C   1 
ATOM   9944  O O   . ASP C 1 344 ? 35.751  -16.097 -11.419 1.00 42.56  ? 344 ASP C O   1 
ATOM   9945  C CB  . ASP C 1 344 ? 33.679  -17.183 -9.268  1.00 53.95  ? 344 ASP C CB  1 
ATOM   9946  C CG  . ASP C 1 344 ? 32.334  -16.701 -9.795  1.00 61.82  ? 344 ASP C CG  1 
ATOM   9947  O OD1 . ASP C 1 344 ? 32.323  -15.678 -10.558 1.00 57.75  ? 344 ASP C OD1 1 
ATOM   9948  O OD2 . ASP C 1 344 ? 31.298  -17.322 -9.400  1.00 61.85  ? 344 ASP C OD2 1 
ATOM   9949  N N   . GLU C 1 345 ? 34.414  -17.446 -12.649 1.00 45.60  ? 345 GLU C N   1 
ATOM   9950  C CA  . GLU C 1 345 ? 34.680  -16.857 -13.950 1.00 50.24  ? 345 GLU C CA  1 
ATOM   9951  C C   . GLU C 1 345 ? 34.396  -15.360 -13.944 1.00 48.32  ? 345 GLU C C   1 
ATOM   9952  O O   . GLU C 1 345 ? 35.213  -14.570 -14.392 1.00 56.55  ? 345 GLU C O   1 
ATOM   9953  C CB  . GLU C 1 345 ? 33.782  -17.507 -15.000 1.00 61.98  ? 345 GLU C CB  1 
ATOM   9954  C CG  . GLU C 1 345 ? 34.059  -18.983 -15.254 1.00 77.22  ? 345 GLU C CG  1 
ATOM   9955  C CD  . GLU C 1 345 ? 35.136  -19.259 -16.292 1.00 77.86  ? 345 GLU C CD  1 
ATOM   9956  O OE1 . GLU C 1 345 ? 36.295  -18.857 -16.068 1.00 78.99  ? 345 GLU C OE1 1 
ATOM   9957  O OE2 . GLU C 1 345 ? 34.804  -19.861 -17.332 1.00 88.52  ? 345 GLU C OE2 1 
ATOM   9958  N N   . LEU C 1 346 ? 33.214  -14.966 -13.471 1.00 49.64  ? 346 LEU C N   1 
ATOM   9959  C CA  . LEU C 1 346 ? 32.839  -13.560 -13.457 1.00 45.38  ? 346 LEU C CA  1 
ATOM   9960  C C   . LEU C 1 346 ? 33.768  -12.815 -12.502 1.00 39.24  ? 346 LEU C C   1 
ATOM   9961  O O   . LEU C 1 346 ? 34.206  -11.713 -12.786 1.00 38.25  ? 346 LEU C O   1 
ATOM   9962  C CB  . LEU C 1 346 ? 31.367  -13.395 -13.054 1.00 41.70  ? 346 LEU C CB  1 
ATOM   9963  C CG  . LEU C 1 346 ? 30.357  -14.202 -13.864 1.00 41.69  ? 346 LEU C CG  1 
ATOM   9964  C CD1 . LEU C 1 346 ? 28.935  -13.874 -13.441 1.00 42.95  ? 346 LEU C CD1 1 
ATOM   9965  C CD2 . LEU C 1 346 ? 30.519  -13.955 -15.360 1.00 40.63  ? 346 LEU C CD2 1 
ATOM   9966  N N   . PHE C 1 347 ? 34.126  -13.433 -11.384 1.00 41.59  ? 347 PHE C N   1 
ATOM   9967  C CA  . PHE C 1 347 ? 35.104  -12.796 -10.517 1.00 41.93  ? 347 PHE C CA  1 
ATOM   9968  C C   . PHE C 1 347 ? 36.433  -12.594 -11.255 1.00 45.58  ? 347 PHE C C   1 
ATOM   9969  O O   . PHE C 1 347 ? 37.055  -11.532 -11.143 1.00 39.52  ? 347 PHE C O   1 
ATOM   9970  C CB  . PHE C 1 347 ? 35.296  -13.590 -9.231  1.00 39.75  ? 347 PHE C CB  1 
ATOM   9971  C CG  . PHE C 1 347 ? 36.490  -13.124 -8.450  1.00 41.89  ? 347 PHE C CG  1 
ATOM   9972  C CD1 . PHE C 1 347 ? 36.576  -11.821 -8.030  1.00 38.05  ? 347 PHE C CD1 1 
ATOM   9973  C CD2 . PHE C 1 347 ? 37.560  -13.969 -8.217  1.00 51.01  ? 347 PHE C CD2 1 
ATOM   9974  C CE1 . PHE C 1 347 ? 37.694  -11.376 -7.350  1.00 46.80  ? 347 PHE C CE1 1 
ATOM   9975  C CE2 . PHE C 1 347 ? 38.684  -13.524 -7.541  1.00 53.40  ? 347 PHE C CE2 1 
ATOM   9976  C CZ  . PHE C 1 347 ? 38.741  -12.230 -7.098  1.00 52.18  ? 347 PHE C CZ  1 
ATOM   9977  N N   . LYS C 1 348 ? 36.857  -13.596 -12.042 1.00 44.94  ? 348 LYS C N   1 
ATOM   9978  C CA  . LYS C 1 348 ? 38.139  -13.490 -12.725 1.00 43.62  ? 348 LYS C CA  1 
ATOM   9979  C C   . LYS C 1 348 ? 38.120  -12.275 -13.634 1.00 43.38  ? 348 LYS C C   1 
ATOM   9980  O O   . LYS C 1 348 ? 39.156  -11.642 -13.808 1.00 54.13  ? 348 LYS C O   1 
ATOM   9981  C CB  . LYS C 1 348 ? 38.490  -14.788 -13.458 1.00 52.95  ? 348 LYS C CB  1 
ATOM   9982  C CG  . LYS C 1 348 ? 38.844  -15.926 -12.508 1.00 59.86  ? 348 LYS C CG  1 
ATOM   9983  C CD  . LYS C 1 348 ? 39.855  -16.941 -13.000 1.00 78.60  ? 348 LYS C CD  1 
ATOM   9984  C CE  . LYS C 1 348 ? 40.683  -17.508 -11.858 1.00 87.68  ? 348 LYS C CE  1 
ATOM   9985  N NZ  . LYS C 1 348 ? 41.433  -18.723 -12.260 1.00 99.06  ? 348 LYS C NZ  1 
ATOM   9986  N N   . ILE C 1 349 ? 36.938  -11.889 -14.146 1.00 44.08  ? 349 ILE C N   1 
ATOM   9987  C CA  . ILE C 1 349 ? 36.874  -10.732 -15.022 1.00 39.59  ? 349 ILE C CA  1 
ATOM   9988  C C   . ILE C 1 349 ? 36.916  -9.439  -14.202 1.00 41.47  ? 349 ILE C C   1 
ATOM   9989  O O   . ILE C 1 349 ? 37.513  -8.447  -14.632 1.00 45.00  ? 349 ILE C O   1 
ATOM   9990  C CB  . ILE C 1 349 ? 35.657  -10.805 -15.950 1.00 38.06  ? 349 ILE C CB  1 
ATOM   9991  C CG1 . ILE C 1 349 ? 35.750  -12.034 -16.843 1.00 39.44  ? 349 ILE C CG1 1 
ATOM   9992  C CG2 . ILE C 1 349 ? 35.530  -9.521  -16.781 1.00 41.12  ? 349 ILE C CG2 1 
ATOM   9993  C CD1 . ILE C 1 349 ? 34.563  -12.204 -17.764 1.00 44.40  ? 349 ILE C CD1 1 
ATOM   9994  N N   . VAL C 1 350 ? 36.304  -9.453  -13.008 1.00 44.32  ? 350 VAL C N   1 
ATOM   9995  C CA  . VAL C 1 350 ? 36.316  -8.283  -12.137 1.00 45.20  ? 350 VAL C CA  1 
ATOM   9996  C C   . VAL C 1 350 ? 37.760  -7.980  -11.740 1.00 44.90  ? 350 VAL C C   1 
ATOM   9997  O O   . VAL C 1 350 ? 38.154  -6.808  -11.687 1.00 43.68  ? 350 VAL C O   1 
ATOM   9998  C CB  . VAL C 1 350 ? 35.407  -8.495  -10.900 1.00 42.90  ? 350 VAL C CB  1 
ATOM   9999  C CG1 . VAL C 1 350 ? 35.803  -7.658  -9.688  1.00 36.09  ? 350 VAL C CG1 1 
ATOM   10000 C CG2 . VAL C 1 350 ? 33.934  -8.281  -11.242 1.00 43.76  ? 350 VAL C CG2 1 
ATOM   10001 N N   . SER C 1 351 ? 38.508  -9.053  -11.416 1.00 46.86  ? 351 SER C N   1 
ATOM   10002 C CA  . SER C 1 351 ? 39.908  -8.962  -11.007 1.00 48.20  ? 351 SER C CA  1 
ATOM   10003 C C   . SER C 1 351 ? 40.765  -8.415  -12.164 1.00 50.10  ? 351 SER C C   1 
ATOM   10004 O O   . SER C 1 351 ? 41.614  -7.549  -11.987 1.00 49.34  ? 351 SER C O   1 
ATOM   10005 C CB  . SER C 1 351 ? 40.395  -10.322 -10.547 1.00 45.84  ? 351 SER C CB  1 
ATOM   10006 O OG  . SER C 1 351 ? 41.494  -10.181 -9.661  1.00 52.18  ? 351 SER C OG  1 
ATOM   10007 N N   . LEU C 1 352 ? 40.545  -8.941  -13.369 1.00 43.22  ? 352 LEU C N   1 
ATOM   10008 C CA  . LEU C 1 352 ? 41.264  -8.490  -14.540 1.00 46.27  ? 352 LEU C CA  1 
ATOM   10009 C C   . LEU C 1 352 ? 41.002  -6.999  -14.765 1.00 49.60  ? 352 LEU C C   1 
ATOM   10010 O O   . LEU C 1 352 ? 41.912  -6.242  -15.068 1.00 51.52  ? 352 LEU C O   1 
ATOM   10011 C CB  . LEU C 1 352 ? 40.802  -9.341  -15.730 1.00 47.69  ? 352 LEU C CB  1 
ATOM   10012 C CG  . LEU C 1 352 ? 41.718  -9.346  -16.951 1.00 59.05  ? 352 LEU C CG  1 
ATOM   10013 C CD1 . LEU C 1 352 ? 42.966  -10.189 -16.674 1.00 60.65  ? 352 LEU C CD1 1 
ATOM   10014 C CD2 . LEU C 1 352 ? 40.979  -9.872  -18.181 1.00 56.50  ? 352 LEU C CD2 1 
ATOM   10015 N N   . CYS C 1 353 ? 39.749  -6.572  -14.641 1.00 46.94  ? 353 CYS C N   1 
ATOM   10016 C CA  . CYS C 1 353 ? 39.418  -5.170  -14.812 1.00 49.50  ? 353 CYS C CA  1 
ATOM   10017 C C   . CYS C 1 353 ? 40.182  -4.300  -13.814 1.00 50.33  ? 353 CYS C C   1 
ATOM   10018 O O   . CYS C 1 353 ? 40.489  -3.150  -14.128 1.00 49.46  ? 353 CYS C O   1 
ATOM   10019 C CB  . CYS C 1 353 ? 37.924  -4.924  -14.634 1.00 52.70  ? 353 CYS C CB  1 
ATOM   10020 S SG  . CYS C 1 353 ? 36.915  -5.515  -16.012 1.00 50.90  ? 353 CYS C SG  1 
ATOM   10021 N N   . TYR C 1 354 ? 40.424  -4.825  -12.604 1.00 49.16  ? 354 TYR C N   1 
ATOM   10022 C CA  . TYR C 1 354 ? 41.208  -4.131  -11.587 1.00 52.07  ? 354 TYR C CA  1 
ATOM   10023 C C   . TYR C 1 354 ? 42.632  -3.856  -12.101 1.00 58.81  ? 354 TYR C C   1 
ATOM   10024 O O   . TYR C 1 354 ? 43.156  -2.771  -11.874 1.00 57.13  ? 354 TYR C O   1 
ATOM   10025 C CB  . TYR C 1 354 ? 41.232  -4.941  -10.280 1.00 46.18  ? 354 TYR C CB  1 
ATOM   10026 C CG  . TYR C 1 354 ? 41.697  -4.225  -9.030  1.00 43.56  ? 354 TYR C CG  1 
ATOM   10027 C CD1 . TYR C 1 354 ? 41.750  -2.848  -8.957  1.00 38.20  ? 354 TYR C CD1 1 
ATOM   10028 C CD2 . TYR C 1 354 ? 42.094  -4.945  -7.914  1.00 48.11  ? 354 TYR C CD2 1 
ATOM   10029 C CE1 . TYR C 1 354 ? 42.157  -2.200  -7.810  1.00 41.39  ? 354 TYR C CE1 1 
ATOM   10030 C CE2 . TYR C 1 354 ? 42.509  -4.313  -6.750  1.00 48.82  ? 354 TYR C CE2 1 
ATOM   10031 C CZ  . TYR C 1 354 ? 42.522  -2.931  -6.701  1.00 44.48  ? 354 TYR C CZ  1 
ATOM   10032 O OH  . TYR C 1 354 ? 42.920  -2.263  -5.586  1.00 50.42  ? 354 TYR C OH  1 
ATOM   10033 N N   . GLU C 1 355 ? 43.252  -4.814  -12.817 1.00 69.46  ? 355 GLU C N   1 
ATOM   10034 C CA  . GLU C 1 355 ? 44.586  -4.627  -13.393 1.00 69.38  ? 355 GLU C CA  1 
ATOM   10035 C C   . GLU C 1 355 ? 44.576  -3.673  -14.588 1.00 61.68  ? 355 GLU C C   1 
ATOM   10036 O O   . GLU C 1 355 ? 45.526  -2.918  -14.754 1.00 59.17  ? 355 GLU C O   1 
ATOM   10037 C CB  . GLU C 1 355 ? 45.182  -5.923  -13.945 1.00 70.52  ? 355 GLU C CB  1 
ATOM   10038 C CG  . GLU C 1 355 ? 45.411  -7.007  -12.912 1.00 81.08  ? 355 GLU C CG  1 
ATOM   10039 C CD  . GLU C 1 355 ? 45.888  -8.318  -13.520 1.00 94.66  ? 355 GLU C CD  1 
ATOM   10040 O OE1 . GLU C 1 355 ? 45.720  -9.361  -12.862 1.00 97.29  ? 355 GLU C OE1 1 
ATOM   10041 O OE2 . GLU C 1 355 ? 46.428  -8.293  -14.658 1.00 116.47 ? 355 GLU C OE2 1 
ATOM   10042 N N   . VAL C 1 356 ? 43.523  -3.735  -15.426 1.00 56.83  ? 356 VAL C N   1 
ATOM   10043 C CA  . VAL C 1 356 ? 43.535  -3.142  -16.758 1.00 54.95  ? 356 VAL C CA  1 
ATOM   10044 C C   . VAL C 1 356 ? 42.879  -1.763  -16.817 1.00 57.17  ? 356 VAL C C   1 
ATOM   10045 O O   . VAL C 1 356 ? 43.429  -0.848  -17.437 1.00 60.77  ? 356 VAL C O   1 
ATOM   10046 C CB  . VAL C 1 356 ? 42.860  -4.061  -17.780 1.00 47.17  ? 356 VAL C CB  1 
ATOM   10047 C CG1 . VAL C 1 356 ? 42.642  -3.348  -19.106 1.00 43.71  ? 356 VAL C CG1 1 
ATOM   10048 C CG2 . VAL C 1 356 ? 43.668  -5.332  -17.947 1.00 43.97  ? 356 VAL C CG2 1 
ATOM   10049 N N   . ILE C 1 357 ? 41.689  -1.624  -16.222 1.00 54.42  ? 357 ILE C N   1 
ATOM   10050 C CA  . ILE C 1 357 ? 40.845  -0.470  -16.488 1.00 48.97  ? 357 ILE C CA  1 
ATOM   10051 C C   . ILE C 1 357 ? 41.438  0.825   -15.940 1.00 46.58  ? 357 ILE C C   1 
ATOM   10052 O O   . ILE C 1 357 ? 41.313  1.874   -16.581 1.00 45.43  ? 357 ILE C O   1 
ATOM   10053 C CB  . ILE C 1 357 ? 39.413  -0.726  -15.985 1.00 50.71  ? 357 ILE C CB  1 
ATOM   10054 C CG1 . ILE C 1 357 ? 38.769  -1.880  -16.763 1.00 46.22  ? 357 ILE C CG1 1 
ATOM   10055 C CG2 . ILE C 1 357 ? 38.571  0.547   -16.034 1.00 50.84  ? 357 ILE C CG2 1 
ATOM   10056 C CD1 . ILE C 1 357 ? 38.545  -1.577  -18.206 1.00 49.24  ? 357 ILE C CD1 1 
ATOM   10057 N N   . PRO C 1 358 ? 42.042  0.860   -14.735 1.00 50.94  ? 358 PRO C N   1 
ATOM   10058 C CA  . PRO C 1 358 ? 42.658  2.100   -14.263 1.00 63.57  ? 358 PRO C CA  1 
ATOM   10059 C C   . PRO C 1 358 ? 43.679  2.669   -15.257 1.00 63.21  ? 358 PRO C C   1 
ATOM   10060 O O   . PRO C 1 358 ? 43.585  3.837   -15.596 1.00 56.92  ? 358 PRO C O   1 
ATOM   10061 C CB  . PRO C 1 358 ? 43.264  1.692   -12.912 1.00 65.42  ? 358 PRO C CB  1 
ATOM   10062 C CG  . PRO C 1 358 ? 42.396  0.542   -12.452 1.00 59.71  ? 358 PRO C CG  1 
ATOM   10063 C CD  . PRO C 1 358 ? 42.109  -0.216  -13.736 1.00 60.05  ? 358 PRO C CD  1 
ATOM   10064 N N   . GLU C 1 359 ? 44.613  1.847   -15.757 1.00 70.03  ? 359 GLU C N   1 
ATOM   10065 C CA  . GLU C 1 359 ? 45.544  2.289   -16.790 1.00 76.51  ? 359 GLU C CA  1 
ATOM   10066 C C   . GLU C 1 359 ? 44.791  3.027   -17.897 1.00 64.69  ? 359 GLU C C   1 
ATOM   10067 O O   . GLU C 1 359 ? 45.115  4.158   -18.223 1.00 61.70  ? 359 GLU C O   1 
ATOM   10068 C CB  . GLU C 1 359 ? 46.280  1.118   -17.433 1.00 85.62  ? 359 GLU C CB  1 
ATOM   10069 C CG  . GLU C 1 359 ? 47.201  0.358   -16.495 1.00 99.19  ? 359 GLU C CG  1 
ATOM   10070 C CD  . GLU C 1 359 ? 47.654  -0.996  -17.033 1.00 107.73 ? 359 GLU C CD  1 
ATOM   10071 O OE1 . GLU C 1 359 ? 47.134  -1.428  -18.103 1.00 103.01 ? 359 GLU C OE1 1 
ATOM   10072 O OE2 . GLU C 1 359 ? 48.526  -1.625  -16.385 1.00 93.74  ? 359 GLU C OE2 1 
ATOM   10073 N N   . VAL C 1 360 ? 43.729  2.406   -18.413 1.00 63.10  ? 360 VAL C N   1 
ATOM   10074 C CA  . VAL C 1 360 ? 42.987  2.920   -19.554 1.00 59.25  ? 360 VAL C CA  1 
ATOM   10075 C C   . VAL C 1 360 ? 42.298  4.245   -19.243 1.00 61.94  ? 360 VAL C C   1 
ATOM   10076 O O   . VAL C 1 360 ? 42.281  5.136   -20.102 1.00 68.59  ? 360 VAL C O   1 
ATOM   10077 C CB  . VAL C 1 360 ? 41.981  1.873   -20.055 1.00 56.59  ? 360 VAL C CB  1 
ATOM   10078 C CG1 . VAL C 1 360 ? 41.046  2.419   -21.136 1.00 50.69  ? 360 VAL C CG1 1 
ATOM   10079 C CG2 . VAL C 1 360 ? 42.732  0.630   -20.530 1.00 55.89  ? 360 VAL C CG2 1 
ATOM   10080 N N   . LEU C 1 361 ? 41.739  4.390   -18.035 1.00 54.09  ? 361 LEU C N   1 
ATOM   10081 C CA  . LEU C 1 361 ? 40.958  5.584   -17.730 1.00 54.51  ? 361 LEU C CA  1 
ATOM   10082 C C   . LEU C 1 361 ? 41.858  6.792   -17.459 1.00 48.71  ? 361 LEU C C   1 
ATOM   10083 O O   . LEU C 1 361 ? 41.453  7.902   -17.806 1.00 43.94  ? 361 LEU C O   1 
ATOM   10084 C CB  . LEU C 1 361 ? 40.006  5.313   -16.558 1.00 54.48  ? 361 LEU C CB  1 
ATOM   10085 C CG  . LEU C 1 361 ? 38.721  4.559   -16.913 1.00 56.48  ? 361 LEU C CG  1 
ATOM   10086 C CD1 . LEU C 1 361 ? 37.979  4.146   -15.657 1.00 49.38  ? 361 LEU C CD1 1 
ATOM   10087 C CD2 . LEU C 1 361 ? 37.809  5.387   -17.817 1.00 58.23  ? 361 LEU C CD2 1 
ATOM   10088 N N   . LYS C 1 362 ? 43.044  6.572   -16.858 1.00 52.28  ? 362 LYS C N   1 
ATOM   10089 C CA  . LYS C 1 362 ? 44.080  7.604   -16.729 1.00 64.30  ? 362 LYS C CA  1 
ATOM   10090 C C   . LYS C 1 362 ? 44.475  8.207   -18.088 1.00 69.73  ? 362 LYS C C   1 
ATOM   10091 O O   . LYS C 1 362 ? 44.399  9.426   -18.264 1.00 62.70  ? 362 LYS C O   1 
ATOM   10092 C CB  . LYS C 1 362 ? 45.343  7.054   -16.068 1.00 63.17  ? 362 LYS C CB  1 
ATOM   10093 C CG  . LYS C 1 362 ? 45.281  6.920   -14.559 1.00 78.05  ? 362 LYS C CG  1 
ATOM   10094 C CD  . LYS C 1 362 ? 46.444  6.109   -13.997 1.00 92.48  ? 362 LYS C CD  1 
ATOM   10095 C CE  . LYS C 1 362 ? 46.562  6.179   -12.486 1.00 95.09  ? 362 LYS C CE  1 
ATOM   10096 N NZ  . LYS C 1 362 ? 47.635  5.291   -11.973 1.00 91.06  ? 362 LYS C NZ  1 
ATOM   10097 N N   . LYS C 1 363 ? 44.887  7.362   -19.049 1.00 69.48  ? 363 LYS C N   1 
ATOM   10098 C CA  . LYS C 1 363 ? 45.284  7.822   -20.374 1.00 69.10  ? 363 LYS C CA  1 
ATOM   10099 C C   . LYS C 1 363 ? 44.126  8.552   -21.049 1.00 63.71  ? 363 LYS C C   1 
ATOM   10100 O O   . LYS C 1 363 ? 44.327  9.639   -21.583 1.00 72.70  ? 363 LYS C O   1 
ATOM   10101 C CB  . LYS C 1 363 ? 45.788  6.667   -21.249 1.00 76.21  ? 363 LYS C CB  1 
ATOM   10102 C CG  . LYS C 1 363 ? 47.053  5.983   -20.737 1.00 95.63  ? 363 LYS C CG  1 
ATOM   10103 C CD  . LYS C 1 363 ? 47.321  4.568   -21.294 1.00 108.49 ? 363 LYS C CD  1 
ATOM   10104 C CE  . LYS C 1 363 ? 48.223  3.738   -20.390 1.00 108.08 ? 363 LYS C CE  1 
ATOM   10105 N NZ  . LYS C 1 363 ? 48.627  2.446   -21.001 1.00 91.60  ? 363 LYS C NZ  1 
ATOM   10106 N N   . HIS C 1 364 ? 42.923  7.966   -21.027 1.00 62.47  ? 364 HIS C N   1 
ATOM   10107 C CA  . HIS C 1 364 ? 41.718  8.615   -21.543 1.00 64.23  ? 364 HIS C CA  1 
ATOM   10108 C C   . HIS C 1 364 ? 41.508  10.009  -20.938 1.00 66.02  ? 364 HIS C C   1 
ATOM   10109 O O   . HIS C 1 364 ? 41.054  10.910  -21.639 1.00 57.64  ? 364 HIS C O   1 
ATOM   10110 C CB  . HIS C 1 364 ? 40.476  7.756   -21.265 1.00 65.60  ? 364 HIS C CB  1 
ATOM   10111 C CG  . HIS C 1 364 ? 39.227  8.253   -21.913 1.00 63.49  ? 364 HIS C CG  1 
ATOM   10112 N ND1 . HIS C 1 364 ? 38.146  8.734   -21.198 1.00 60.81  ? 364 HIS C ND1 1 
ATOM   10113 C CD2 . HIS C 1 364 ? 38.894  8.347   -23.216 1.00 64.07  ? 364 HIS C CD2 1 
ATOM   10114 C CE1 . HIS C 1 364 ? 37.189  9.094   -22.042 1.00 66.12  ? 364 HIS C CE1 1 
ATOM   10115 N NE2 . HIS C 1 364 ? 37.626  8.878   -23.277 1.00 64.74  ? 364 HIS C NE2 1 
ATOM   10116 N N   . GLY C 1 365 ? 41.754  10.153  -19.620 1.00 66.49  ? 365 GLY C N   1 
ATOM   10117 C CA  . GLY C 1 365 ? 41.979  11.444  -18.973 1.00 65.59  ? 365 GLY C CA  1 
ATOM   10118 C C   . GLY C 1 365 ? 40.731  12.313  -18.767 1.00 71.02  ? 365 GLY C C   1 
ATOM   10119 O O   . GLY C 1 365 ? 40.854  13.518  -18.555 1.00 64.06  ? 365 GLY C O   1 
ATOM   10120 N N   . LYS C 1 366 ? 39.527  11.732  -18.805 1.00 71.11  ? 366 LYS C N   1 
ATOM   10121 C CA  . LYS C 1 366 ? 38.341  12.483  -18.417 1.00 74.43  ? 366 LYS C CA  1 
ATOM   10122 C C   . LYS C 1 366 ? 38.012  12.234  -16.942 1.00 64.09  ? 366 LYS C C   1 
ATOM   10123 O O   . LYS C 1 366 ? 37.647  13.160  -16.233 1.00 68.68  ? 366 LYS C O   1 
ATOM   10124 C CB  . LYS C 1 366 ? 37.183  12.162  -19.366 1.00 74.61  ? 366 LYS C CB  1 
ATOM   10125 C CG  . LYS C 1 366 ? 37.361  12.758  -20.752 1.00 76.27  ? 366 LYS C CG  1 
ATOM   10126 C CD  . LYS C 1 366 ? 36.182  12.587  -21.681 1.00 78.55  ? 366 LYS C CD  1 
ATOM   10127 C CE  . LYS C 1 366 ? 36.517  13.145  -23.052 1.00 91.70  ? 366 LYS C CE  1 
ATOM   10128 N NZ  . LYS C 1 366 ? 35.643  12.601  -24.119 1.00 94.94  ? 366 LYS C NZ  1 
ATOM   10129 N N   . ALA C 1 367 ? 38.162  10.989  -16.482 1.00 64.06  ? 367 ALA C N   1 
ATOM   10130 C CA  . ALA C 1 367 ? 37.770  10.578  -15.142 1.00 62.07  ? 367 ALA C CA  1 
ATOM   10131 C C   . ALA C 1 367 ? 38.706  11.172  -14.090 1.00 63.22  ? 367 ALA C C   1 
ATOM   10132 O O   . ALA C 1 367 ? 39.916  10.960  -14.142 1.00 63.87  ? 367 ALA C O   1 
ATOM   10133 C CB  . ALA C 1 367 ? 37.767  9.071   -15.044 1.00 56.35  ? 367 ALA C CB  1 
ATOM   10134 N N   . LYS C 1 368 ? 38.122  11.910  -13.136 1.00 61.62  ? 368 LYS C N   1 
ATOM   10135 C CA  . LYS C 1 368 ? 38.843  12.387  -11.964 1.00 60.08  ? 368 LYS C CA  1 
ATOM   10136 C C   . LYS C 1 368 ? 39.281  11.180  -11.138 1.00 58.55  ? 368 LYS C C   1 
ATOM   10137 O O   . LYS C 1 368 ? 40.338  11.179  -10.523 1.00 63.05  ? 368 LYS C O   1 
ATOM   10138 C CB  . LYS C 1 368 ? 37.973  13.376  -11.173 1.00 64.93  ? 368 LYS C CB  1 
ATOM   10139 N N   . ASN C 1 369 ? 38.483  10.115  -11.153 1.00 63.76  ? 369 ASN C N   1 
ATOM   10140 C CA  . ASN C 1 369 ? 38.825  8.927   -10.391 1.00 63.10  ? 369 ASN C CA  1 
ATOM   10141 C C   . ASN C 1 369 ? 38.849  7.729   -11.335 1.00 59.66  ? 369 ASN C C   1 
ATOM   10142 O O   . ASN C 1 369 ? 37.784  7.300   -11.797 1.00 56.87  ? 369 ASN C O   1 
ATOM   10143 C CB  . ASN C 1 369 ? 37.851  8.688   -9.237  1.00 63.53  ? 369 ASN C CB  1 
ATOM   10144 C CG  . ASN C 1 369 ? 38.234  7.463   -8.432  1.00 65.48  ? 369 ASN C CG  1 
ATOM   10145 O OD1 . ASN C 1 369 ? 39.410  7.102   -8.376  1.00 59.05  ? 369 ASN C OD1 1 
ATOM   10146 N ND2 . ASN C 1 369 ? 37.256  6.821   -7.811  1.00 65.40  ? 369 ASN C ND2 1 
ATOM   10147 N N   . PRO C 1 370 ? 40.045  7.171   -11.647 1.00 48.68  ? 370 PRO C N   1 
ATOM   10148 C CA  . PRO C 1 370 ? 40.160  6.016   -12.538 1.00 53.33  ? 370 PRO C CA  1 
ATOM   10149 C C   . PRO C 1 370 ? 40.077  4.661   -11.835 1.00 51.02  ? 370 PRO C C   1 
ATOM   10150 O O   . PRO C 1 370 ? 40.219  3.627   -12.467 1.00 51.57  ? 370 PRO C O   1 
ATOM   10151 C CB  . PRO C 1 370 ? 41.569  6.225   -13.111 1.00 58.77  ? 370 PRO C CB  1 
ATOM   10152 C CG  . PRO C 1 370 ? 42.363  6.763   -11.923 1.00 58.99  ? 370 PRO C CG  1 
ATOM   10153 C CD  . PRO C 1 370 ? 41.367  7.646   -11.195 1.00 58.81  ? 370 PRO C CD  1 
ATOM   10154 N N   . TRP C 1 371 ? 39.804  4.693   -10.525 1.00 54.45  ? 371 TRP C N   1 
ATOM   10155 C CA  . TRP C 1 371 ? 39.778  3.516   -9.678  1.00 51.89  ? 371 TRP C CA  1 
ATOM   10156 C C   . TRP C 1 371 ? 38.348  3.000   -9.522  1.00 48.91  ? 371 TRP C C   1 
ATOM   10157 O O   . TRP C 1 371 ? 37.366  3.732   -9.690  1.00 43.35  ? 371 TRP C O   1 
ATOM   10158 C CB  . TRP C 1 371 ? 40.432  3.854   -8.331  1.00 55.40  ? 371 TRP C CB  1 
ATOM   10159 C CG  . TRP C 1 371 ? 41.854  4.289   -8.492  1.00 58.89  ? 371 TRP C CG  1 
ATOM   10160 C CD1 . TRP C 1 371 ? 42.359  5.555   -8.393  1.00 62.72  ? 371 TRP C CD1 1 
ATOM   10161 C CD2 . TRP C 1 371 ? 42.955  3.440   -8.841  1.00 64.97  ? 371 TRP C CD2 1 
ATOM   10162 N NE1 . TRP C 1 371 ? 43.704  5.552   -8.645  1.00 65.93  ? 371 TRP C NE1 1 
ATOM   10163 C CE2 . TRP C 1 371 ? 44.100  4.264   -8.915  1.00 73.04  ? 371 TRP C CE2 1 
ATOM   10164 C CE3 . TRP C 1 371 ? 43.082  2.075   -9.105  1.00 57.74  ? 371 TRP C CE3 1 
ATOM   10165 C CZ2 . TRP C 1 371 ? 45.356  3.755   -9.240  1.00 61.69  ? 371 TRP C CZ2 1 
ATOM   10166 C CZ3 . TRP C 1 371 ? 44.328  1.574   -9.408  1.00 65.63  ? 371 TRP C CZ3 1 
ATOM   10167 C CH2 . TRP C 1 371 ? 45.447  2.405   -9.479  1.00 57.80  ? 371 TRP C CH2 1 
ATOM   10168 N N   . PRO C 1 372 ? 38.188  1.721   -9.147  1.00 43.33  ? 372 PRO C N   1 
ATOM   10169 C CA  . PRO C 1 372 ? 36.864  1.155   -8.928  1.00 43.21  ? 372 PRO C CA  1 
ATOM   10170 C C   . PRO C 1 372 ? 36.212  1.620   -7.622  1.00 46.79  ? 372 PRO C C   1 
ATOM   10171 O O   . PRO C 1 372 ? 36.898  2.001   -6.662  1.00 42.36  ? 372 PRO C O   1 
ATOM   10172 C CB  . PRO C 1 372 ? 37.133  -0.354  -8.933  1.00 45.98  ? 372 PRO C CB  1 
ATOM   10173 C CG  . PRO C 1 372 ? 38.563  -0.504  -8.486  1.00 47.77  ? 372 PRO C CG  1 
ATOM   10174 C CD  . PRO C 1 372 ? 39.274  0.778   -8.857  1.00 48.22  ? 372 PRO C CD  1 
ATOM   10175 N N   . ASN C 1 373 ? 34.867  1.592   -7.634  1.00 44.56  ? 373 ASN C N   1 
ATOM   10176 C CA  . ASN C 1 373 ? 34.024  1.804   -6.464  1.00 43.24  ? 373 ASN C CA  1 
ATOM   10177 C C   . ASN C 1 373 ? 33.455  0.477   -5.955  1.00 40.51  ? 373 ASN C C   1 
ATOM   10178 O O   . ASN C 1 373 ? 33.689  -0.586  -6.517  1.00 47.13  ? 373 ASN C O   1 
ATOM   10179 C CB  . ASN C 1 373 ? 32.926  2.836   -6.742  1.00 43.91  ? 373 ASN C CB  1 
ATOM   10180 C CG  . ASN C 1 373 ? 32.051  2.484   -7.917  1.00 45.51  ? 373 ASN C CG  1 
ATOM   10181 O OD1 . ASN C 1 373 ? 31.527  1.378   -7.979  1.00 51.61  ? 373 ASN C OD1 1 
ATOM   10182 N ND2 . ASN C 1 373 ? 31.935  3.389   -8.875  1.00 50.38  ? 373 ASN C ND2 1 
ATOM   10183 N N   . VAL C 1 374 ? 32.678  0.551   -4.876  1.00 46.34  ? 374 VAL C N   1 
ATOM   10184 C CA  . VAL C 1 374 ? 32.055  -0.608  -4.249  1.00 44.76  ? 374 VAL C CA  1 
ATOM   10185 C C   . VAL C 1 374 ? 31.224  -1.397  -5.266  1.00 42.72  ? 374 VAL C C   1 
ATOM   10186 O O   . VAL C 1 374 ? 31.189  -2.626  -5.213  1.00 35.79  ? 374 VAL C O   1 
ATOM   10187 C CB  . VAL C 1 374 ? 31.202  -0.178  -3.035  1.00 45.81  ? 374 VAL C CB  1 
ATOM   10188 C CG1 . VAL C 1 374 ? 30.084  0.784   -3.414  1.00 45.30  ? 374 VAL C CG1 1 
ATOM   10189 C CG2 . VAL C 1 374 ? 30.625  -1.370  -2.299  1.00 50.18  ? 374 VAL C CG2 1 
ATOM   10190 N N   . ASP C 1 375 ? 30.562  -0.692  -6.189  1.00 41.66  ? 375 ASP C N   1 
ATOM   10191 C CA  . ASP C 1 375 ? 29.561  -1.323  -7.036  1.00 46.53  ? 375 ASP C CA  1 
ATOM   10192 C C   . ASP C 1 375 ? 30.197  -2.174  -8.138  1.00 44.33  ? 375 ASP C C   1 
ATOM   10193 O O   . ASP C 1 375 ? 29.511  -2.929  -8.816  1.00 41.11  ? 375 ASP C O   1 
ATOM   10194 C CB  . ASP C 1 375 ? 28.630  -0.269  -7.629  1.00 56.54  ? 375 ASP C CB  1 
ATOM   10195 C CG  . ASP C 1 375 ? 27.755  0.420   -6.595  1.00 57.53  ? 375 ASP C CG  1 
ATOM   10196 O OD1 . ASP C 1 375 ? 27.068  -0.296  -5.807  1.00 55.12  ? 375 ASP C OD1 1 
ATOM   10197 O OD2 . ASP C 1 375 ? 27.726  1.660   -6.611  1.00 70.22  ? 375 ASP C OD2 1 
ATOM   10198 N N   . ALA C 1 376 ? 31.518  -2.073  -8.315  1.00 39.14  ? 376 ALA C N   1 
ATOM   10199 C CA  . ALA C 1 376 ? 32.185  -2.909  -9.288  1.00 38.33  ? 376 ALA C CA  1 
ATOM   10200 C C   . ALA C 1 376 ? 32.294  -4.354  -8.798  1.00 37.07  ? 376 ALA C C   1 
ATOM   10201 O O   . ALA C 1 376 ? 32.505  -5.231  -9.604  1.00 36.97  ? 376 ALA C O   1 
ATOM   10202 C CB  . ALA C 1 376 ? 33.549  -2.339  -9.594  1.00 43.13  ? 376 ALA C CB  1 
ATOM   10203 N N   . HIS C 1 377 ? 32.122  -4.611  -7.492  1.00 36.94  ? 377 HIS C N   1 
ATOM   10204 C CA  . HIS C 1 377 ? 32.428  -5.914  -6.923  1.00 38.85  ? 377 HIS C CA  1 
ATOM   10205 C C   . HIS C 1 377 ? 31.225  -6.672  -6.355  1.00 37.41  ? 377 HIS C C   1 
ATOM   10206 O O   . HIS C 1 377 ? 31.298  -7.899  -6.196  1.00 37.79  ? 377 HIS C O   1 
ATOM   10207 C CB  . HIS C 1 377 ? 33.477  -5.768  -5.809  1.00 40.90  ? 377 HIS C CB  1 
ATOM   10208 C CG  . HIS C 1 377 ? 34.462  -6.862  -5.886  1.00 41.84  ? 377 HIS C CG  1 
ATOM   10209 N ND1 . HIS C 1 377 ? 34.049  -8.165  -5.971  1.00 42.25  ? 377 HIS C ND1 1 
ATOM   10210 C CD2 . HIS C 1 377 ? 35.802  -6.871  -5.979  1.00 40.63  ? 377 HIS C CD2 1 
ATOM   10211 C CE1 . HIS C 1 377 ? 35.118  -8.940  -6.066  1.00 44.42  ? 377 HIS C CE1 1 
ATOM   10212 N NE2 . HIS C 1 377 ? 36.194  -8.171  -6.064  1.00 40.37  ? 377 HIS C NE2 1 
ATOM   10213 N N   . SER C 1 378 ? 30.122  -5.981  -6.054  1.00 37.49  ? 378 SER C N   1 
ATOM   10214 C CA  . SER C 1 378 ? 29.075  -6.574  -5.225  1.00 38.60  ? 378 SER C CA  1 
ATOM   10215 C C   . SER C 1 378 ? 28.297  -7.619  -6.008  1.00 36.78  ? 378 SER C C   1 
ATOM   10216 O O   . SER C 1 378 ? 27.970  -8.692  -5.491  1.00 37.99  ? 378 SER C O   1 
ATOM   10217 C CB  . SER C 1 378 ? 28.174  -5.504  -4.681  1.00 39.05  ? 378 SER C CB  1 
ATOM   10218 O OG  . SER C 1 378 ? 27.808  -4.597  -5.721  1.00 46.68  ? 378 SER C OG  1 
ATOM   10219 N N   . GLY C 1 379 ? 27.985  -7.268  -7.260  1.00 36.35  ? 379 GLY C N   1 
ATOM   10220 C CA  . GLY C 1 379 ? 27.193  -8.100  -8.156  1.00 32.83  ? 379 GLY C CA  1 
ATOM   10221 C C   . GLY C 1 379 ? 27.735  -9.518  -8.287  1.00 36.59  ? 379 GLY C C   1 
ATOM   10222 O O   . GLY C 1 379 ? 26.992  -10.483 -8.157  1.00 35.96  ? 379 GLY C O   1 
ATOM   10223 N N   . VAL C 1 380 ? 29.041  -9.664  -8.549  1.00 35.94  ? 380 VAL C N   1 
ATOM   10224 C CA  . VAL C 1 380 ? 29.523  -10.997 -8.846  1.00 38.99  ? 380 VAL C CA  1 
ATOM   10225 C C   . VAL C 1 380 ? 29.435  -11.861 -7.594  1.00 41.14  ? 380 VAL C C   1 
ATOM   10226 O O   . VAL C 1 380 ? 29.270  -13.064 -7.749  1.00 41.25  ? 380 VAL C O   1 
ATOM   10227 C CB  . VAL C 1 380 ? 30.948  -11.035 -9.439  1.00 41.06  ? 380 VAL C CB  1 
ATOM   10228 C CG1 . VAL C 1 380 ? 30.957  -10.440 -10.823 1.00 36.21  ? 380 VAL C CG1 1 
ATOM   10229 C CG2 . VAL C 1 380 ? 31.995  -10.389 -8.536  1.00 47.90  ? 380 VAL C CG2 1 
ATOM   10230 N N   . LEU C 1 381 ? 29.572  -11.264 -6.386  1.00 40.75  ? 381 LEU C N   1 
ATOM   10231 C CA  . LEU C 1 381 ? 29.440  -12.020 -5.144  1.00 38.23  ? 381 LEU C CA  1 
ATOM   10232 C C   . LEU C 1 381 ? 28.008  -12.536 -5.022  1.00 39.47  ? 381 LEU C C   1 
ATOM   10233 O O   . LEU C 1 381 ? 27.774  -13.733 -4.893  1.00 44.21  ? 381 LEU C O   1 
ATOM   10234 C CB  . LEU C 1 381 ? 29.836  -11.169 -3.931  1.00 36.35  ? 381 LEU C CB  1 
ATOM   10235 C CG  . LEU C 1 381 ? 31.281  -10.650 -3.909  1.00 37.77  ? 381 LEU C CG  1 
ATOM   10236 C CD1 . LEU C 1 381 ? 31.571  -9.886  -2.629  1.00 39.68  ? 381 LEU C CD1 1 
ATOM   10237 C CD2 . LEU C 1 381 ? 32.274  -11.794 -4.054  1.00 42.84  ? 381 LEU C CD2 1 
ATOM   10238 N N   . LEU C 1 382 ? 27.033  -11.637 -5.091  1.00 38.63  ? 382 LEU C N   1 
ATOM   10239 C CA  . LEU C 1 382 ? 25.637  -12.037 -4.967  1.00 37.12  ? 382 LEU C CA  1 
ATOM   10240 C C   . LEU C 1 382 ? 25.317  -13.130 -6.001  1.00 40.03  ? 382 LEU C C   1 
ATOM   10241 O O   . LEU C 1 382 ? 24.717  -14.154 -5.671  1.00 35.84  ? 382 LEU C O   1 
ATOM   10242 C CB  . LEU C 1 382 ? 24.768  -10.792 -5.168  1.00 35.77  ? 382 LEU C CB  1 
ATOM   10243 C CG  . LEU C 1 382 ? 24.884  -9.724  -4.091  1.00 35.77  ? 382 LEU C CG  1 
ATOM   10244 C CD1 . LEU C 1 382 ? 24.202  -8.448  -4.506  1.00 37.23  ? 382 LEU C CD1 1 
ATOM   10245 C CD2 . LEU C 1 382 ? 24.284  -10.194 -2.777  1.00 35.13  ? 382 LEU C CD2 1 
ATOM   10246 N N   . TRP C 1 383 ? 25.706  -12.903 -7.266  1.00 40.20  ? 383 TRP C N   1 
ATOM   10247 C CA  . TRP C 1 383 ? 25.387  -13.826 -8.354  1.00 39.50  ? 383 TRP C CA  1 
ATOM   10248 C C   . TRP C 1 383 ? 25.994  -15.198 -8.093  1.00 37.80  ? 383 TRP C C   1 
ATOM   10249 O O   . TRP C 1 383 ? 25.336  -16.188 -8.289  1.00 38.85  ? 383 TRP C O   1 
ATOM   10250 C CB  . TRP C 1 383 ? 25.877  -13.261 -9.692  1.00 40.90  ? 383 TRP C CB  1 
ATOM   10251 C CG  . TRP C 1 383 ? 25.499  -14.086 -10.879 1.00 39.74  ? 383 TRP C CG  1 
ATOM   10252 C CD1 . TRP C 1 383 ? 26.167  -15.165 -11.382 1.00 37.66  ? 383 TRP C CD1 1 
ATOM   10253 C CD2 . TRP C 1 383 ? 24.354  -13.894 -11.721 1.00 38.60  ? 383 TRP C CD2 1 
ATOM   10254 N NE1 . TRP C 1 383 ? 25.515  -15.655 -12.484 1.00 41.65  ? 383 TRP C NE1 1 
ATOM   10255 C CE2 . TRP C 1 383 ? 24.378  -14.925 -12.691 1.00 44.76  ? 383 TRP C CE2 1 
ATOM   10256 C CE3 . TRP C 1 383 ? 23.273  -13.006 -11.711 1.00 45.12  ? 383 TRP C CE3 1 
ATOM   10257 C CZ2 . TRP C 1 383 ? 23.376  -15.066 -13.651 1.00 47.05  ? 383 TRP C CZ2 1 
ATOM   10258 C CZ3 . TRP C 1 383 ? 22.305  -13.112 -12.692 1.00 41.87  ? 383 TRP C CZ3 1 
ATOM   10259 C CH2 . TRP C 1 383 ? 22.344  -14.145 -13.629 1.00 46.88  ? 383 TRP C CH2 1 
ATOM   10260 N N   . HIS C 1 384 ? 27.247  -15.254 -7.625  1.00 42.08  ? 384 HIS C N   1 
ATOM   10261 C CA  . HIS C 1 384 ? 27.913  -16.517 -7.319  1.00 40.38  ? 384 HIS C CA  1 
ATOM   10262 C C   . HIS C 1 384 ? 27.079  -17.382 -6.370  1.00 40.33  ? 384 HIS C C   1 
ATOM   10263 O O   . HIS C 1 384 ? 26.956  -18.587 -6.571  1.00 43.31  ? 384 HIS C O   1 
ATOM   10264 C CB  . HIS C 1 384 ? 29.302  -16.279 -6.720  1.00 45.92  ? 384 HIS C CB  1 
ATOM   10265 C CG  . HIS C 1 384 ? 29.971  -17.552 -6.302  1.00 46.28  ? 384 HIS C CG  1 
ATOM   10266 N ND1 . HIS C 1 384 ? 30.639  -18.380 -7.189  1.00 40.56  ? 384 HIS C ND1 1 
ATOM   10267 C CD2 . HIS C 1 384 ? 30.104  -18.102 -5.078  1.00 39.44  ? 384 HIS C CD2 1 
ATOM   10268 C CE1 . HIS C 1 384 ? 31.104  -19.430 -6.527  1.00 41.58  ? 384 HIS C CE1 1 
ATOM   10269 N NE2 . HIS C 1 384 ? 30.773  -19.297 -5.259  1.00 46.28  ? 384 HIS C NE2 1 
ATOM   10270 N N   . TYR C 1 385 ? 26.479  -16.791 -5.333  1.00 42.32  ? 385 TYR C N   1 
ATOM   10271 C CA  . TYR C 1 385 ? 25.758  -17.588 -4.349  1.00 38.25  ? 385 TYR C CA  1 
ATOM   10272 C C   . TYR C 1 385 ? 24.307  -17.708 -4.761  1.00 39.07  ? 385 TYR C C   1 
ATOM   10273 O O   . TYR C 1 385 ? 23.479  -18.209 -4.015  1.00 41.36  ? 385 TYR C O   1 
ATOM   10274 C CB  . TYR C 1 385 ? 25.864  -16.957 -2.960  1.00 43.04  ? 385 TYR C CB  1 
ATOM   10275 C CG  . TYR C 1 385 ? 27.241  -17.084 -2.381  1.00 39.83  ? 385 TYR C CG  1 
ATOM   10276 C CD1 . TYR C 1 385 ? 27.690  -18.310 -1.920  1.00 40.23  ? 385 TYR C CD1 1 
ATOM   10277 C CD2 . TYR C 1 385 ? 28.109  -16.005 -2.344  1.00 37.24  ? 385 TYR C CD2 1 
ATOM   10278 C CE1 . TYR C 1 385 ? 28.972  -18.455 -1.404  1.00 40.87  ? 385 TYR C CE1 1 
ATOM   10279 C CE2 . TYR C 1 385 ? 29.401  -16.138 -1.851  1.00 37.93  ? 385 TYR C CE2 1 
ATOM   10280 C CZ  . TYR C 1 385 ? 29.827  -17.368 -1.368  1.00 38.21  ? 385 TYR C CZ  1 
ATOM   10281 O OH  . TYR C 1 385 ? 31.106  -17.541 -0.906  1.00 42.55  ? 385 TYR C OH  1 
ATOM   10282 N N   . GLY C 1 386 ? 23.964  -17.197 -5.938  1.00 42.20  ? 386 GLY C N   1 
ATOM   10283 C CA  . GLY C 1 386 ? 22.637  -17.485 -6.446  1.00 40.33  ? 386 GLY C CA  1 
ATOM   10284 C C   . GLY C 1 386 ? 21.574  -16.438 -6.122  1.00 41.05  ? 386 GLY C C   1 
ATOM   10285 O O   . GLY C 1 386 ? 20.415  -16.711 -6.389  1.00 37.81  ? 386 GLY C O   1 
ATOM   10286 N N   . ILE C 1 387 ? 21.954  -15.219 -5.672  1.00 46.60  ? 387 ILE C N   1 
ATOM   10287 C CA  . ILE C 1 387 ? 21.029  -14.088 -5.704  1.00 38.64  ? 387 ILE C CA  1 
ATOM   10288 C C   . ILE C 1 387 ? 21.176  -13.386 -7.051  1.00 41.20  ? 387 ILE C C   1 
ATOM   10289 O O   . ILE C 1 387 ? 22.073  -12.573 -7.258  1.00 39.91  ? 387 ILE C O   1 
ATOM   10290 C CB  . ILE C 1 387 ? 21.204  -13.103 -4.538  1.00 41.82  ? 387 ILE C CB  1 
ATOM   10291 C CG1 . ILE C 1 387 ? 21.185  -13.755 -3.152  1.00 44.95  ? 387 ILE C CG1 1 
ATOM   10292 C CG2 . ILE C 1 387 ? 20.134  -12.033 -4.618  1.00 41.25  ? 387 ILE C CG2 1 
ATOM   10293 C CD1 . ILE C 1 387 ? 22.519  -14.179 -2.643  1.00 53.29  ? 387 ILE C CD1 1 
ATOM   10294 N N   . ARG C 1 388 ? 20.216  -13.660 -7.937  1.00 41.13  ? 388 ARG C N   1 
ATOM   10295 C CA  . ARG C 1 388 ? 20.324  -13.393 -9.354  1.00 43.09  ? 388 ARG C CA  1 
ATOM   10296 C C   . ARG C 1 388 ? 19.315  -12.362 -9.818  1.00 41.73  ? 388 ARG C C   1 
ATOM   10297 O O   . ARG C 1 388 ? 19.298  -12.013 -10.986 1.00 42.25  ? 388 ARG C O   1 
ATOM   10298 C CB  . ARG C 1 388 ? 20.101  -14.699 -10.109 1.00 50.18  ? 388 ARG C CB  1 
ATOM   10299 C CG  . ARG C 1 388 ? 21.124  -15.744 -9.709  1.00 53.99  ? 388 ARG C CG  1 
ATOM   10300 C CD  . ARG C 1 388 ? 21.509  -16.725 -10.779 1.00 64.51  ? 388 ARG C CD  1 
ATOM   10301 N NE  . ARG C 1 388 ? 22.818  -17.223 -10.359 1.00 76.44  ? 388 ARG C NE  1 
ATOM   10302 C CZ  . ARG C 1 388 ? 23.508  -18.178 -10.972 1.00 73.86  ? 388 ARG C CZ  1 
ATOM   10303 N NH1 . ARG C 1 388 ? 22.997  -18.768 -12.049 1.00 61.84  ? 388 ARG C NH1 1 
ATOM   10304 N NH2 . ARG C 1 388 ? 24.691  -18.530 -10.479 1.00 62.82  ? 388 ARG C NH2 1 
ATOM   10305 N N   . GLU C 1 389 ? 18.508  -11.863 -8.888  1.00 45.15  ? 389 GLU C N   1 
ATOM   10306 C CA  . GLU C 1 389 ? 17.416  -10.975 -9.224  1.00 40.46  ? 389 GLU C CA  1 
ATOM   10307 C C   . GLU C 1 389 ? 17.946  -9.553  -9.192  1.00 37.04  ? 389 GLU C C   1 
ATOM   10308 O O   . GLU C 1 389 ? 17.914  -8.913  -8.168  1.00 38.63  ? 389 GLU C O   1 
ATOM   10309 C CB  . GLU C 1 389 ? 16.276  -11.279 -8.256  1.00 40.72  ? 389 GLU C CB  1 
ATOM   10310 C CG  . GLU C 1 389 ? 15.734  -12.698 -8.430  1.00 45.95  ? 389 GLU C CG  1 
ATOM   10311 C CD  . GLU C 1 389 ? 16.500  -13.872 -7.819  1.00 44.71  ? 389 GLU C CD  1 
ATOM   10312 O OE1 . GLU C 1 389 ? 16.166  -14.999 -8.136  1.00 46.49  ? 389 GLU C OE1 1 
ATOM   10313 O OE2 . GLU C 1 389 ? 17.388  -13.666 -7.000  1.00 39.43  ? 389 GLU C OE2 1 
ATOM   10314 N N   . TYR C 1 390 ? 18.494  -9.100  -10.325 1.00 40.66  ? 390 TYR C N   1 
ATOM   10315 C CA  . TYR C 1 390 ? 19.169  -7.814  -10.464 1.00 37.42  ? 390 TYR C CA  1 
ATOM   10316 C C   . TYR C 1 390 ? 18.441  -6.657  -9.745  1.00 43.45  ? 390 TYR C C   1 
ATOM   10317 O O   . TYR C 1 390 ? 19.056  -5.843  -9.057  1.00 37.33  ? 390 TYR C O   1 
ATOM   10318 C CB  . TYR C 1 390 ? 19.277  -7.454  -11.954 1.00 43.27  ? 390 TYR C CB  1 
ATOM   10319 C CG  . TYR C 1 390 ? 20.059  -8.393  -12.848 1.00 45.93  ? 390 TYR C CG  1 
ATOM   10320 C CD1 . TYR C 1 390 ? 21.445  -8.404  -12.852 1.00 47.94  ? 390 TYR C CD1 1 
ATOM   10321 C CD2 . TYR C 1 390 ? 19.416  -9.264  -13.716 1.00 44.83  ? 390 TYR C CD2 1 
ATOM   10322 C CE1 . TYR C 1 390 ? 22.165  -9.256  -13.680 1.00 46.26  ? 390 TYR C CE1 1 
ATOM   10323 C CE2 . TYR C 1 390 ? 20.118  -10.142 -14.526 1.00 42.46  ? 390 TYR C CE2 1 
ATOM   10324 C CZ  . TYR C 1 390 ? 21.500  -10.114 -14.540 1.00 45.76  ? 390 TYR C CZ  1 
ATOM   10325 O OH  . TYR C 1 390 ? 22.209  -10.957 -15.357 1.00 41.38  ? 390 TYR C OH  1 
ATOM   10326 N N   . ASP C 1 391 ? 17.128  -6.507  -9.965  1.00 39.84  ? 391 ASP C N   1 
ATOM   10327 C CA  . ASP C 1 391 ? 16.444  -5.306  -9.516  1.00 38.12  ? 391 ASP C CA  1 
ATOM   10328 C C   . ASP C 1 391 ? 16.424  -5.305  -7.992  1.00 36.40  ? 391 ASP C C   1 
ATOM   10329 O O   . ASP C 1 391 ? 16.356  -4.263  -7.367  1.00 30.53  ? 391 ASP C O   1 
ATOM   10330 C CB  . ASP C 1 391 ? 15.026  -5.208  -10.081 1.00 42.50  ? 391 ASP C CB  1 
ATOM   10331 C CG  . ASP C 1 391 ? 14.953  -4.842  -11.559 1.00 47.45  ? 391 ASP C CG  1 
ATOM   10332 O OD1 . ASP C 1 391 ? 16.019  -4.466  -12.096 1.00 43.95  ? 391 ASP C OD1 1 
ATOM   10333 O OD2 . ASP C 1 391 ? 13.803  -4.886  -12.151 1.00 47.06  ? 391 ASP C OD2 1 
ATOM   10334 N N   . PHE C 1 392 ? 16.484  -6.494  -7.406  1.00 31.57  ? 392 PHE C N   1 
ATOM   10335 C CA  . PHE C 1 392 ? 16.366  -6.626  -5.982  1.00 31.83  ? 392 PHE C CA  1 
ATOM   10336 C C   . PHE C 1 392 ? 17.661  -6.175  -5.308  1.00 32.67  ? 392 PHE C C   1 
ATOM   10337 O O   . PHE C 1 392 ? 17.673  -5.882  -4.129  1.00 33.06  ? 392 PHE C O   1 
ATOM   10338 C CB  . PHE C 1 392 ? 16.003  -8.070  -5.645  1.00 31.79  ? 392 PHE C CB  1 
ATOM   10339 C CG  . PHE C 1 392 ? 15.708  -8.229  -4.175  1.00 32.94  ? 392 PHE C CG  1 
ATOM   10340 C CD1 . PHE C 1 392 ? 14.462  -7.923  -3.673  1.00 30.73  ? 392 PHE C CD1 1 
ATOM   10341 C CD2 . PHE C 1 392 ? 16.700  -8.614  -3.287  1.00 34.98  ? 392 PHE C CD2 1 
ATOM   10342 C CE1 . PHE C 1 392 ? 14.199  -8.031  -2.319  1.00 33.64  ? 392 PHE C CE1 1 
ATOM   10343 C CE2 . PHE C 1 392 ? 16.411  -8.786  -1.942  1.00 34.46  ? 392 PHE C CE2 1 
ATOM   10344 C CZ  . PHE C 1 392 ? 15.169  -8.481  -1.466  1.00 32.70  ? 392 PHE C CZ  1 
ATOM   10345 N N   . TYR C 1 393 ? 18.765  -6.100  -6.052  1.00 32.71  ? 393 TYR C N   1 
ATOM   10346 C CA  . TYR C 1 393 ? 20.041  -5.716  -5.471  1.00 31.34  ? 393 TYR C CA  1 
ATOM   10347 C C   . TYR C 1 393 ? 19.923  -4.359  -4.769  1.00 34.44  ? 393 TYR C C   1 
ATOM   10348 O O   . TYR C 1 393 ? 20.576  -4.109  -3.765  1.00 37.01  ? 393 TYR C O   1 
ATOM   10349 C CB  . TYR C 1 393 ? 21.122  -5.641  -6.563  1.00 29.03  ? 393 TYR C CB  1 
ATOM   10350 C CG  . TYR C 1 393 ? 21.584  -6.938  -7.178  1.00 34.28  ? 393 TYR C CG  1 
ATOM   10351 C CD1 . TYR C 1 393 ? 21.129  -8.162  -6.731  1.00 37.39  ? 393 TYR C CD1 1 
ATOM   10352 C CD2 . TYR C 1 393 ? 22.563  -6.950  -8.170  1.00 35.17  ? 393 TYR C CD2 1 
ATOM   10353 C CE1 . TYR C 1 393 ? 21.609  -9.350  -7.238  1.00 35.89  ? 393 TYR C CE1 1 
ATOM   10354 C CE2 . TYR C 1 393 ? 23.022  -8.127  -8.717  1.00 30.94  ? 393 TYR C CE2 1 
ATOM   10355 C CZ  . TYR C 1 393 ? 22.542  -9.340  -8.257  1.00 36.60  ? 393 TYR C CZ  1 
ATOM   10356 O OH  . TYR C 1 393 ? 22.961  -10.564 -8.773  1.00 32.53  ? 393 TYR C OH  1 
ATOM   10357 N N   . THR C 1 394 ? 19.144  -3.433  -5.348  1.00 36.56  ? 394 THR C N   1 
ATOM   10358 C CA  . THR C 1 394 ? 18.991  -2.126  -4.756  1.00 32.68  ? 394 THR C CA  1 
ATOM   10359 C C   . THR C 1 394 ? 18.275  -2.227  -3.403  1.00 34.72  ? 394 THR C C   1 
ATOM   10360 O O   . THR C 1 394 ? 18.482  -1.392  -2.527  1.00 38.66  ? 394 THR C O   1 
ATOM   10361 C CB  . THR C 1 394 ? 18.332  -1.183  -5.760  1.00 37.91  ? 394 THR C CB  1 
ATOM   10362 O OG1 . THR C 1 394 ? 18.970  -1.267  -7.033  1.00 38.92  ? 394 THR C OG1 1 
ATOM   10363 C CG2 . THR C 1 394 ? 18.406  0.259   -5.313  1.00 42.57  ? 394 THR C CG2 1 
ATOM   10364 N N   . VAL C 1 395 ? 17.468  -3.264  -3.192  1.00 33.22  ? 395 VAL C N   1 
ATOM   10365 C CA  . VAL C 1 395 ? 16.783  -3.438  -1.919  1.00 35.47  ? 395 VAL C CA  1 
ATOM   10366 C C   . VAL C 1 395 ? 17.769  -3.892  -0.851  1.00 37.61  ? 395 VAL C C   1 
ATOM   10367 O O   . VAL C 1 395 ? 17.724  -3.428  0.292   1.00 32.34  ? 395 VAL C O   1 
ATOM   10368 C CB  . VAL C 1 395 ? 15.563  -4.377  -2.022  1.00 34.60  ? 395 VAL C CB  1 
ATOM   10369 C CG1 . VAL C 1 395 ? 14.939  -4.616  -0.656  1.00 36.20  ? 395 VAL C CG1 1 
ATOM   10370 C CG2 . VAL C 1 395 ? 14.528  -3.839  -2.990  1.00 32.14  ? 395 VAL C CG2 1 
ATOM   10371 N N   . LEU C 1 396 ? 18.722  -4.739  -1.235  1.00 39.52  ? 396 LEU C N   1 
ATOM   10372 C CA  . LEU C 1 396 ? 19.762  -5.109  -0.294  1.00 36.60  ? 396 LEU C CA  1 
ATOM   10373 C C   . LEU C 1 396 ? 20.572  -3.868  0.080   1.00 35.69  ? 396 LEU C C   1 
ATOM   10374 O O   . LEU C 1 396 ? 20.981  -3.691  1.220   1.00 35.69  ? 396 LEU C O   1 
ATOM   10375 C CB  . LEU C 1 396 ? 20.650  -6.199  -0.881  1.00 33.57  ? 396 LEU C CB  1 
ATOM   10376 C CG  . LEU C 1 396 ? 19.966  -7.532  -1.176  1.00 31.99  ? 396 LEU C CG  1 
ATOM   10377 C CD1 . LEU C 1 396 ? 20.877  -8.394  -2.040  1.00 33.63  ? 396 LEU C CD1 1 
ATOM   10378 C CD2 . LEU C 1 396 ? 19.617  -8.261  0.103   1.00 32.37  ? 396 LEU C CD2 1 
ATOM   10379 N N   . PHE C 1 397 ? 20.808  -2.986  -0.867  1.00 36.45  ? 397 PHE C N   1 
ATOM   10380 C CA  . PHE C 1 397 ? 21.547  -1.768  -0.555  1.00 35.83  ? 397 PHE C CA  1 
ATOM   10381 C C   . PHE C 1 397 ? 20.740  -0.941  0.446   1.00 34.36  ? 397 PHE C C   1 
ATOM   10382 O O   . PHE C 1 397 ? 21.279  -0.419  1.414   1.00 35.60  ? 397 PHE C O   1 
ATOM   10383 C CB  . PHE C 1 397 ? 21.895  -1.089  -1.879  1.00 37.75  ? 397 PHE C CB  1 
ATOM   10384 C CG  . PHE C 1 397 ? 22.788  0.116   -1.849  1.00 43.64  ? 397 PHE C CG  1 
ATOM   10385 C CD1 . PHE C 1 397 ? 23.397  0.555   -0.695  1.00 51.76  ? 397 PHE C CD1 1 
ATOM   10386 C CD2 . PHE C 1 397 ? 23.057  0.793   -3.032  1.00 61.19  ? 397 PHE C CD2 1 
ATOM   10387 C CE1 . PHE C 1 397 ? 24.234  1.664   -0.711  1.00 51.79  ? 397 PHE C CE1 1 
ATOM   10388 C CE2 . PHE C 1 397 ? 23.888  1.902   -3.051  1.00 62.89  ? 397 PHE C CE2 1 
ATOM   10389 C CZ  . PHE C 1 397 ? 24.484  2.330   -1.886  1.00 55.48  ? 397 PHE C CZ  1 
ATOM   10390 N N   . GLY C 1 398 ? 19.425  -0.828  0.217   1.00 34.18  ? 398 GLY C N   1 
ATOM   10391 C CA  . GLY C 1 398 ? 18.579  -0.021  1.069   1.00 29.71  ? 398 GLY C CA  1 
ATOM   10392 C C   . GLY C 1 398 ? 18.553  -0.535  2.499   1.00 26.79  ? 398 GLY C C   1 
ATOM   10393 O O   . GLY C 1 398 ? 18.581  0.236   3.436   1.00 30.65  ? 398 GLY C O   1 
ATOM   10394 N N   . VAL C 1 399 ? 18.417  -1.846  2.656   1.00 33.09  ? 399 VAL C N   1 
ATOM   10395 C CA  . VAL C 1 399 ? 18.419  -2.462  3.959   1.00 30.76  ? 399 VAL C CA  1 
ATOM   10396 C C   . VAL C 1 399 ? 19.674  -2.038  4.719   1.00 35.06  ? 399 VAL C C   1 
ATOM   10397 O O   . VAL C 1 399 ? 19.591  -1.664  5.878   1.00 37.43  ? 399 VAL C O   1 
ATOM   10398 C CB  . VAL C 1 399 ? 18.294  -3.983  3.850   1.00 31.25  ? 399 VAL C CB  1 
ATOM   10399 C CG1 . VAL C 1 399 ? 18.487  -4.643  5.220   1.00 35.77  ? 399 VAL C CG1 1 
ATOM   10400 C CG2 . VAL C 1 399 ? 16.960  -4.390  3.263   1.00 35.51  ? 399 VAL C CG2 1 
ATOM   10401 N N   . SER C 1 400 ? 20.841  -2.077  4.057   1.00 33.36  ? 400 SER C N   1 
ATOM   10402 C CA  . SER C 1 400 ? 22.091  -1.745  4.713   1.00 32.93  ? 400 SER C CA  1 
ATOM   10403 C C   . SER C 1 400 ? 22.116  -0.264  5.105   1.00 38.88  ? 400 SER C C   1 
ATOM   10404 O O   . SER C 1 400 ? 22.536  0.110   6.195   1.00 40.62  ? 400 SER C O   1 
ATOM   10405 C CB  . SER C 1 400 ? 23.215  -2.058  3.765   1.00 32.31  ? 400 SER C CB  1 
ATOM   10406 O OG  . SER C 1 400 ? 24.430  -1.580  4.270   1.00 35.07  ? 400 SER C OG  1 
ATOM   10407 N N   . ARG C 1 401 ? 21.717  0.581   4.146   1.00 35.28  ? 401 ARG C N   1 
ATOM   10408 C CA  . ARG C 1 401 ? 21.851  2.007   4.257   1.00 38.71  ? 401 ARG C CA  1 
ATOM   10409 C C   . ARG C 1 401 ? 20.951  2.536   5.380   1.00 36.93  ? 401 ARG C C   1 
ATOM   10410 O O   . ARG C 1 401 ? 21.180  3.621   5.897   1.00 40.76  ? 401 ARG C O   1 
ATOM   10411 C CB  . ARG C 1 401 ? 21.557  2.623   2.883   1.00 38.59  ? 401 ARG C CB  1 
ATOM   10412 C CG  . ARG C 1 401 ? 21.808  4.118   2.812   1.00 39.16  ? 401 ARG C CG  1 
ATOM   10413 C CD  . ARG C 1 401 ? 23.163  4.500   3.406   1.00 41.90  ? 401 ARG C CD  1 
ATOM   10414 N NE  . ARG C 1 401 ? 24.365  3.959   2.765   1.00 38.06  ? 401 ARG C NE  1 
ATOM   10415 C CZ  . ARG C 1 401 ? 24.946  4.464   1.679   1.00 40.40  ? 401 ARG C CZ  1 
ATOM   10416 N NH1 . ARG C 1 401 ? 24.354  5.438   1.010   1.00 42.82  ? 401 ARG C NH1 1 
ATOM   10417 N NH2 . ARG C 1 401 ? 26.124  4.000   1.267   1.00 35.49  ? 401 ARG C NH2 1 
ATOM   10418 N N   . ALA C 1 402 ? 19.952  1.765   5.781   1.00 36.39  ? 402 ALA C N   1 
ATOM   10419 C CA  . ALA C 1 402 ? 19.132  2.143   6.923   1.00 36.30  ? 402 ALA C CA  1 
ATOM   10420 C C   . ALA C 1 402 ? 19.968  2.253   8.202   1.00 35.26  ? 402 ALA C C   1 
ATOM   10421 O O   . ALA C 1 402 ? 19.622  3.020   9.098   1.00 29.83  ? 402 ALA C O   1 
ATOM   10422 C CB  . ALA C 1 402 ? 18.022  1.149   7.111   1.00 34.99  ? 402 ALA C CB  1 
ATOM   10423 N N   . LEU C 1 403 ? 21.076  1.505   8.294   1.00 36.86  ? 403 LEU C N   1 
ATOM   10424 C CA  . LEU C 1 403 ? 21.908  1.612   9.484   1.00 32.82  ? 403 LEU C CA  1 
ATOM   10425 C C   . LEU C 1 403 ? 22.455  3.032   9.616   1.00 36.01  ? 403 LEU C C   1 
ATOM   10426 O O   . LEU C 1 403 ? 22.389  3.660   10.665  1.00 35.62  ? 403 LEU C O   1 
ATOM   10427 C CB  . LEU C 1 403 ? 23.019  0.590   9.385   1.00 33.21  ? 403 LEU C CB  1 
ATOM   10428 C CG  . LEU C 1 403 ? 22.602  -0.867  9.318   1.00 35.54  ? 403 LEU C CG  1 
ATOM   10429 C CD1 . LEU C 1 403 ? 23.799  -1.712  8.919   1.00 38.73  ? 403 LEU C CD1 1 
ATOM   10430 C CD2 . LEU C 1 403 ? 22.033  -1.362  10.641  1.00 38.56  ? 403 LEU C CD2 1 
ATOM   10431 N N   . GLY C 1 404 ? 22.954  3.574   8.511   1.00 39.91  ? 404 GLY C N   1 
ATOM   10432 C CA  . GLY C 1 404 ? 23.480  4.922   8.523   1.00 37.25  ? 404 GLY C CA  1 
ATOM   10433 C C   . GLY C 1 404 ? 22.389  5.963   8.685   1.00 35.56  ? 404 GLY C C   1 
ATOM   10434 O O   . GLY C 1 404 ? 22.531  6.881   9.477   1.00 38.40  ? 404 GLY C O   1 
ATOM   10435 N N   . CYS C 1 405 ? 21.337  5.855   7.873   1.00 35.55  ? 405 CYS C N   1 
ATOM   10436 C CA  . CYS C 1 405 ? 20.199  6.763   7.961   1.00 34.17  ? 405 CYS C CA  1 
ATOM   10437 C C   . CYS C 1 405 ? 19.590  6.799   9.370   1.00 30.45  ? 405 CYS C C   1 
ATOM   10438 O O   . CYS C 1 405 ? 19.285  7.865   9.897   1.00 32.73  ? 405 CYS C O   1 
ATOM   10439 C CB  . CYS C 1 405 ? 19.147  6.397   6.918   1.00 34.21  ? 405 CYS C CB  1 
ATOM   10440 S SG  . CYS C 1 405 ? 19.756  6.668   5.230   1.00 42.47  ? 405 CYS C SG  1 
ATOM   10441 N N   . THR C 1 406 ? 19.389  5.666   10.018  1.00 34.48  ? 406 THR C N   1 
ATOM   10442 C CA  . THR C 1 406 ? 18.778  5.730   11.346  1.00 35.16  ? 406 THR C CA  1 
ATOM   10443 C C   . THR C 1 406 ? 19.704  6.452   12.335  1.00 42.10  ? 406 THR C C   1 
ATOM   10444 O O   . THR C 1 406 ? 19.304  7.377   13.064  1.00 38.79  ? 406 THR C O   1 
ATOM   10445 C CB  . THR C 1 406 ? 18.416  4.351   11.870  1.00 33.50  ? 406 THR C CB  1 
ATOM   10446 O OG1 . THR C 1 406 ? 19.547  3.520   11.699  1.00 30.31  ? 406 THR C OG1 1 
ATOM   10447 C CG2 . THR C 1 406 ? 17.243  3.732   11.163  1.00 32.86  ? 406 THR C CG2 1 
ATOM   10448 N N   . ALA C 1 407 ? 20.974  6.063   12.310  1.00 45.65  ? 407 ALA C N   1 
ATOM   10449 C CA  . ALA C 1 407 ? 21.950  6.635   13.211  1.00 43.37  ? 407 ALA C CA  1 
ATOM   10450 C C   . ALA C 1 407 ? 22.008  8.147   13.031  1.00 41.62  ? 407 ALA C C   1 
ATOM   10451 O O   . ALA C 1 407 ? 21.891  8.896   14.006  1.00 40.08  ? 407 ALA C O   1 
ATOM   10452 C CB  . ALA C 1 407 ? 23.277  5.961   12.998  1.00 48.41  ? 407 ALA C CB  1 
ATOM   10453 N N   . GLN C 1 408 ? 22.128  8.606   11.783  1.00 42.42  ? 408 GLN C N   1 
ATOM   10454 C CA  . GLN C 1 408 ? 22.151  10.038  11.506  1.00 43.56  ? 408 GLN C CA  1 
ATOM   10455 C C   . GLN C 1 408 ? 20.904  10.751  12.027  1.00 43.27  ? 408 GLN C C   1 
ATOM   10456 O O   . GLN C 1 408 ? 21.014  11.858  12.563  1.00 42.19  ? 408 GLN C O   1 
ATOM   10457 C CB  . GLN C 1 408 ? 22.253  10.308  9.997   1.00 46.02  ? 408 GLN C CB  1 
ATOM   10458 C CG  . GLN C 1 408 ? 23.668  10.089  9.481   1.00 53.25  ? 408 GLN C CG  1 
ATOM   10459 C CD  . GLN C 1 408 ? 23.897  10.454  8.035   1.00 52.20  ? 408 GLN C CD  1 
ATOM   10460 O OE1 . GLN C 1 408 ? 23.750  11.603  7.627   1.00 59.52  ? 408 GLN C OE1 1 
ATOM   10461 N NE2 . GLN C 1 408 ? 24.316  9.475   7.248   1.00 51.95  ? 408 GLN C NE2 1 
ATOM   10462 N N   . ALA C 1 409 ? 19.711  10.173  11.776  1.00 42.49  ? 409 ALA C N   1 
ATOM   10463 C CA  . ALA C 1 409 ? 18.475  10.882  12.075  1.00 41.41  ? 409 ALA C CA  1 
ATOM   10464 C C   . ALA C 1 409 ? 18.301  11.048  13.594  1.00 40.92  ? 409 ALA C C   1 
ATOM   10465 O O   . ALA C 1 409 ? 17.836  12.097  14.037  1.00 40.45  ? 409 ALA C O   1 
ATOM   10466 C CB  . ALA C 1 409 ? 17.309  10.193  11.433  1.00 42.61  ? 409 ALA C CB  1 
ATOM   10467 N N   . ILE C 1 410 ? 18.684  10.020  14.357  1.00 38.12  ? 410 ILE C N   1 
ATOM   10468 C CA  . ILE C 1 410 ? 18.678  9.997   15.816  1.00 37.54  ? 410 ILE C CA  1 
ATOM   10469 C C   . ILE C 1 410 ? 19.597  11.072  16.373  1.00 41.06  ? 410 ILE C C   1 
ATOM   10470 O O   . ILE C 1 410 ? 19.211  11.768  17.295  1.00 42.60  ? 410 ILE C O   1 
ATOM   10471 C CB  . ILE C 1 410 ? 19.137  8.616   16.337  1.00 35.87  ? 410 ILE C CB  1 
ATOM   10472 C CG1 . ILE C 1 410 ? 18.130  7.527   16.006  1.00 38.91  ? 410 ILE C CG1 1 
ATOM   10473 C CG2 . ILE C 1 410 ? 19.422  8.625   17.837  1.00 38.33  ? 410 ILE C CG2 1 
ATOM   10474 C CD1 . ILE C 1 410 ? 18.631  6.168   16.333  1.00 42.24  ? 410 ILE C CD1 1 
ATOM   10475 N N   . LEU C 1 411 ? 20.848  11.097  15.885  1.00 46.74  ? 411 LEU C N   1 
ATOM   10476 C CA  . LEU C 1 411 ? 21.864  12.039  16.323  1.00 42.54  ? 411 LEU C CA  1 
ATOM   10477 C C   . LEU C 1 411 ? 21.401  13.454  16.042  1.00 41.89  ? 411 LEU C C   1 
ATOM   10478 O O   . LEU C 1 411 ? 21.542  14.323  16.886  1.00 40.66  ? 411 LEU C O   1 
ATOM   10479 C CB  . LEU C 1 411 ? 23.201  11.765  15.609  1.00 39.13  ? 411 LEU C CB  1 
ATOM   10480 C CG  . LEU C 1 411 ? 23.891  10.481  16.073  1.00 41.56  ? 411 LEU C CG  1 
ATOM   10481 C CD1 . LEU C 1 411 ? 25.102  10.145  15.227  1.00 43.23  ? 411 LEU C CD1 1 
ATOM   10482 C CD2 . LEU C 1 411 ? 24.280  10.584  17.533  1.00 45.63  ? 411 LEU C CD2 1 
ATOM   10483 N N   . VAL C 1 412 ? 20.948  13.703  14.815  1.00 41.83  ? 412 VAL C N   1 
ATOM   10484 C CA  . VAL C 1 412 ? 20.642  15.068  14.417  1.00 38.44  ? 412 VAL C CA  1 
ATOM   10485 C C   . VAL C 1 412 ? 19.436  15.568  15.229  1.00 44.40  ? 412 VAL C C   1 
ATOM   10486 O O   . VAL C 1 412 ? 19.324  16.773  15.472  1.00 39.55  ? 412 VAL C O   1 
ATOM   10487 C CB  . VAL C 1 412 ? 20.490  15.155  12.886  1.00 46.59  ? 412 VAL C CB  1 
ATOM   10488 C CG1 . VAL C 1 412 ? 19.576  16.265  12.433  1.00 63.05  ? 412 VAL C CG1 1 
ATOM   10489 C CG2 . VAL C 1 412 ? 21.857  15.261  12.198  1.00 46.75  ? 412 VAL C CG2 1 
ATOM   10490 N N   . ARG C 1 413 ? 18.535  14.668  15.674  1.00 38.26  ? 413 ARG C N   1 
ATOM   10491 C CA  . ARG C 1 413 ? 17.440  15.089  16.543  1.00 44.66  ? 413 ARG C CA  1 
ATOM   10492 C C   . ARG C 1 413 ? 17.944  15.239  17.993  1.00 44.64  ? 413 ARG C C   1 
ATOM   10493 O O   . ARG C 1 413 ? 17.353  15.985  18.775  1.00 45.44  ? 413 ARG C O   1 
ATOM   10494 C CB  . ARG C 1 413 ? 16.232  14.152  16.437  1.00 39.45  ? 413 ARG C CB  1 
ATOM   10495 C CG  . ARG C 1 413 ? 15.600  14.064  15.058  1.00 40.44  ? 413 ARG C CG  1 
ATOM   10496 C CD  . ARG C 1 413 ? 14.616  15.139  14.685  1.00 40.21  ? 413 ARG C CD  1 
ATOM   10497 N NE  . ARG C 1 413 ? 15.040  16.453  15.133  1.00 52.80  ? 413 ARG C NE  1 
ATOM   10498 C CZ  . ARG C 1 413 ? 15.618  17.356  14.356  1.00 53.76  ? 413 ARG C CZ  1 
ATOM   10499 N NH1 . ARG C 1 413 ? 16.056  17.005  13.159  1.00 58.04  ? 413 ARG C NH1 1 
ATOM   10500 N NH2 . ARG C 1 413 ? 15.824  18.580  14.804  1.00 48.67  ? 413 ARG C NH2 1 
ATOM   10501 N N   . GLY C 1 414 ? 19.008  14.511  18.339  1.00 40.44  ? 414 GLY C N   1 
ATOM   10502 C CA  . GLY C 1 414 ? 19.771  14.710  19.563  1.00 43.15  ? 414 GLY C CA  1 
ATOM   10503 C C   . GLY C 1 414 ? 20.389  16.105  19.608  1.00 43.40  ? 414 GLY C C   1 
ATOM   10504 O O   . GLY C 1 414 ? 20.245  16.804  20.603  1.00 58.14  ? 414 GLY C O   1 
ATOM   10505 N N   . TYR C 1 415 ? 20.996  16.527  18.502  1.00 40.58  ? 415 TYR C N   1 
ATOM   10506 C CA  . TYR C 1 415 ? 21.675  17.809  18.393  1.00 39.97  ? 415 TYR C CA  1 
ATOM   10507 C C   . TYR C 1 415 ? 20.697  18.963  18.282  1.00 43.74  ? 415 TYR C C   1 
ATOM   10508 O O   . TYR C 1 415 ? 21.060  20.118  18.520  1.00 49.28  ? 415 TYR C O   1 
ATOM   10509 C CB  . TYR C 1 415 ? 22.504  17.941  17.104  1.00 43.74  ? 415 TYR C CB  1 
ATOM   10510 C CG  . TYR C 1 415 ? 23.668  16.999  16.923  1.00 41.51  ? 415 TYR C CG  1 
ATOM   10511 C CD1 . TYR C 1 415 ? 23.996  16.052  17.871  1.00 41.36  ? 415 TYR C CD1 1 
ATOM   10512 C CD2 . TYR C 1 415 ? 24.430  17.032  15.759  1.00 47.21  ? 415 TYR C CD2 1 
ATOM   10513 C CE1 . TYR C 1 415 ? 25.036  15.155  17.667  1.00 41.84  ? 415 TYR C CE1 1 
ATOM   10514 C CE2 . TYR C 1 415 ? 25.480  16.149  15.551  1.00 41.95  ? 415 TYR C CE2 1 
ATOM   10515 C CZ  . TYR C 1 415 ? 25.778  15.203  16.505  1.00 38.20  ? 415 TYR C CZ  1 
ATOM   10516 O OH  . TYR C 1 415 ? 26.789  14.291  16.340  1.00 46.71  ? 415 TYR C OH  1 
ATOM   10517 N N   . MET C 1 416 ? 19.495  18.640  17.804  1.00 46.74  ? 416 MET C N   1 
ATOM   10518 C CA  . MET C 1 416 ? 18.410  19.638  17.622  1.00 40.72  ? 416 MET C CA  1 
ATOM   10519 C C   . MET C 1 416 ? 18.735  20.581  16.462  1.00 38.79  ? 416 MET C C   1 
ATOM   10520 O O   . MET C 1 416 ? 18.524  21.781  16.615  1.00 44.16  ? 416 MET C O   1 
ATOM   10521 C CB  . MET C 1 416 ? 18.132  20.415  18.911  1.00 45.50  ? 416 MET C CB  1 
ATOM   10522 C CG  . MET C 1 416 ? 17.618  19.540  20.028  1.00 55.71  ? 416 MET C CG  1 
ATOM   10523 S SD  . MET C 1 416 ? 17.107  20.506  21.458  1.00 69.02  ? 416 MET C SD  1 
ATOM   10524 C CE  . MET C 1 416 ? 16.752  19.191  22.619  1.00 74.95  ? 416 MET C CE  1 
ATOM   10525 N N   . LEU C 1 417 ? 19.152  20.040  15.320  1.00 38.26  ? 417 LEU C N   1 
ATOM   10526 C CA  . LEU C 1 417 ? 19.379  20.919  14.186  1.00 40.40  ? 417 LEU C CA  1 
ATOM   10527 C C   . LEU C 1 417 ? 18.041  21.354  13.616  1.00 39.39  ? 417 LEU C C   1 
ATOM   10528 O O   . LEU C 1 417 ? 17.025  20.692  13.776  1.00 42.89  ? 417 LEU C O   1 
ATOM   10529 C CB  . LEU C 1 417 ? 20.243  20.241  13.127  1.00 44.73  ? 417 LEU C CB  1 
ATOM   10530 C CG  . LEU C 1 417 ? 21.622  19.777  13.583  1.00 44.61  ? 417 LEU C CG  1 
ATOM   10531 C CD1 . LEU C 1 417 ? 22.352  19.122  12.417  1.00 49.01  ? 417 LEU C CD1 1 
ATOM   10532 C CD2 . LEU C 1 417 ? 22.419  20.930  14.167  1.00 47.44  ? 417 LEU C CD2 1 
ATOM   10533 N N   . PRO C 1 418 ? 17.996  22.534  12.990  1.00 40.29  ? 418 PRO C N   1 
ATOM   10534 C CA  . PRO C 1 418 ? 16.759  23.043  12.401  1.00 39.75  ? 418 PRO C CA  1 
ATOM   10535 C C   . PRO C 1 418 ? 16.400  22.471  11.028  1.00 45.09  ? 418 PRO C C   1 
ATOM   10536 O O   . PRO C 1 418 ? 17.126  21.667  10.464  1.00 55.08  ? 418 PRO C O   1 
ATOM   10537 C CB  . PRO C 1 418 ? 17.079  24.550  12.274  1.00 40.94  ? 418 PRO C CB  1 
ATOM   10538 C CG  . PRO C 1 418 ? 18.593  24.599  12.007  1.00 40.76  ? 418 PRO C CG  1 
ATOM   10539 C CD  . PRO C 1 418 ? 19.139  23.462  12.850  1.00 43.60  ? 418 PRO C CD  1 
ATOM   10540 N N   . ILE C 1 419 ? 15.271  22.944  10.514  1.00 43.71  ? 419 ILE C N   1 
ATOM   10541 C CA  . ILE C 1 419 ? 14.733  22.566  9.225   1.00 42.82  ? 419 ILE C CA  1 
ATOM   10542 C C   . ILE C 1 419 ? 15.664  23.033  8.130   1.00 42.83  ? 419 ILE C C   1 
ATOM   10543 O O   . ILE C 1 419 ? 16.203  24.114  8.180   1.00 51.28  ? 419 ILE C O   1 
ATOM   10544 C CB  . ILE C 1 419 ? 13.322  23.144  9.029   1.00 37.66  ? 419 ILE C CB  1 
ATOM   10545 C CG1 . ILE C 1 419 ? 12.678  22.601  7.760   1.00 37.34  ? 419 ILE C CG1 1 
ATOM   10546 C CG2 . ILE C 1 419 ? 13.292  24.677  9.068   1.00 37.72  ? 419 ILE C CG2 1 
ATOM   10547 C CD1 . ILE C 1 419 ? 11.218  22.924  7.692   1.00 40.31  ? 419 ILE C CD1 1 
ATOM   10548 N N   . GLU C 1 420 ? 15.794  22.215  7.108   1.00 44.05  ? 420 GLU C N   1 
ATOM   10549 C CA  . GLU C 1 420 ? 16.681  22.529  6.012   1.00 46.72  ? 420 GLU C CA  1 
ATOM   10550 C C   . GLU C 1 420 ? 15.901  23.405  5.043   1.00 47.87  ? 420 GLU C C   1 
ATOM   10551 O O   . GLU C 1 420 ? 14.841  22.993  4.579   1.00 49.77  ? 420 GLU C O   1 
ATOM   10552 C CB  . GLU C 1 420 ? 17.144  21.195  5.429   1.00 52.03  ? 420 GLU C CB  1 
ATOM   10553 C CG  . GLU C 1 420 ? 18.336  21.308  4.523   1.00 64.68  ? 420 GLU C CG  1 
ATOM   10554 C CD  . GLU C 1 420 ? 18.742  20.013  3.841   1.00 61.01  ? 420 GLU C CD  1 
ATOM   10555 O OE1 . GLU C 1 420 ? 18.630  19.961  2.595   1.00 53.78  ? 420 GLU C OE1 1 
ATOM   10556 O OE2 . GLU C 1 420 ? 19.188  19.079  4.556   1.00 62.74  ? 420 GLU C OE2 1 
ATOM   10557 N N   . ARG C 1 421 ? 16.399  24.616  4.762   1.00 51.46  ? 421 ARG C N   1 
ATOM   10558 C CA  . ARG C 1 421 ? 15.691  25.570  3.915   1.00 51.42  ? 421 ARG C CA  1 
ATOM   10559 C C   . ARG C 1 421 ? 16.703  26.466  3.189   1.00 54.18  ? 421 ARG C C   1 
ATOM   10560 O O   . ARG C 1 421 ? 16.844  27.655  3.503   1.00 43.70  ? 421 ARG C O   1 
ATOM   10561 C CB  . ARG C 1 421 ? 14.729  26.417  4.755   1.00 55.46  ? 421 ARG C CB  1 
ATOM   10562 C CG  . ARG C 1 421 ? 13.502  26.947  4.025   1.00 62.06  ? 421 ARG C CG  1 
ATOM   10563 C CD  . ARG C 1 421 ? 13.688  28.141  3.096   1.00 71.68  ? 421 ARG C CD  1 
ATOM   10564 N NE  . ARG C 1 421 ? 12.418  28.432  2.411   1.00 84.64  ? 421 ARG C NE  1 
ATOM   10565 C CZ  . ARG C 1 421 ? 12.240  28.582  1.088   1.00 89.46  ? 421 ARG C CZ  1 
ATOM   10566 N NH1 . ARG C 1 421 ? 13.264  28.682  0.255   1.00 87.71  ? 421 ARG C NH1 1 
ATOM   10567 N NH2 . ARG C 1 421 ? 11.017  28.680  0.592   1.00 83.24  ? 421 ARG C NH2 1 
ATOM   10568 N N   . PRO C 1 422 ? 17.434  25.931  2.184   1.00 49.99  ? 422 PRO C N   1 
ATOM   10569 C CA  . PRO C 1 422 ? 18.285  26.747  1.316   1.00 48.32  ? 422 PRO C CA  1 
ATOM   10570 C C   . PRO C 1 422 ? 17.478  27.748  0.509   1.00 47.04  ? 422 PRO C C   1 
ATOM   10571 O O   . PRO C 1 422 ? 16.262  27.672  0.462   1.00 44.76  ? 422 PRO C O   1 
ATOM   10572 C CB  . PRO C 1 422 ? 18.908  25.728  0.359   1.00 49.17  ? 422 PRO C CB  1 
ATOM   10573 C CG  . PRO C 1 422 ? 17.922  24.603  0.359   1.00 53.34  ? 422 PRO C CG  1 
ATOM   10574 C CD  . PRO C 1 422 ? 17.487  24.514  1.811   1.00 50.45  ? 422 PRO C CD  1 
ATOM   10575 N N   . LYS C 1 423 ? 18.180  28.682  -0.128  1.00 47.53  ? 423 LYS C N   1 
ATOM   10576 C CA  . LYS C 1 423 ? 17.551  29.650  -0.996  1.00 44.98  ? 423 LYS C CA  1 
ATOM   10577 C C   . LYS C 1 423 ? 17.787  29.177  -2.424  1.00 43.13  ? 423 LYS C C   1 
ATOM   10578 O O   . LYS C 1 423 ? 18.900  28.803  -2.773  1.00 46.50  ? 423 LYS C O   1 
ATOM   10579 C CB  . LYS C 1 423 ? 18.165  31.035  -0.734  1.00 53.61  ? 423 LYS C CB  1 
ATOM   10580 C CG  . LYS C 1 423 ? 17.708  32.174  -1.644  1.00 58.79  ? 423 LYS C CG  1 
ATOM   10581 C CD  . LYS C 1 423 ? 16.422  32.848  -1.171  1.00 74.90  ? 423 LYS C CD  1 
ATOM   10582 C CE  . LYS C 1 423 ? 15.903  33.871  -2.162  1.00 79.55  ? 423 LYS C CE  1 
ATOM   10583 N NZ  . LYS C 1 423 ? 14.798  34.672  -1.587  1.00 88.27  ? 423 LYS C NZ  1 
ATOM   10584 N N   . SER C 1 424 ? 16.748  29.226  -3.253  1.00 40.81  ? 424 SER C N   1 
ATOM   10585 C CA  . SER C 1 424 ? 16.912  28.971  -4.663  1.00 48.22  ? 424 SER C CA  1 
ATOM   10586 C C   . SER C 1 424 ? 17.056  30.303  -5.407  1.00 52.51  ? 424 SER C C   1 
ATOM   10587 O O   . SER C 1 424 ? 16.530  31.327  -4.955  1.00 51.69  ? 424 SER C O   1 
ATOM   10588 C CB  . SER C 1 424 ? 15.768  28.133  -5.190  1.00 47.20  ? 424 SER C CB  1 
ATOM   10589 O OG  . SER C 1 424 ? 14.534  28.821  -5.100  1.00 43.83  ? 424 SER C OG  1 
ATOM   10590 N N   . ILE C 1 425 ? 17.752  30.249  -6.559  1.00 45.61  ? 425 ILE C N   1 
ATOM   10591 C CA  . ILE C 1 425 ? 17.955  31.405  -7.416  1.00 49.36  ? 425 ILE C CA  1 
ATOM   10592 C C   . ILE C 1 425 ? 17.304  31.146  -8.760  1.00 45.98  ? 425 ILE C C   1 
ATOM   10593 O O   . ILE C 1 425 ? 17.150  30.005  -9.165  1.00 46.89  ? 425 ILE C O   1 
ATOM   10594 C CB  . ILE C 1 425 ? 19.453  31.716  -7.589  1.00 55.50  ? 425 ILE C CB  1 
ATOM   10595 C CG1 . ILE C 1 425 ? 20.165  30.598  -8.368  1.00 56.90  ? 425 ILE C CG1 1 
ATOM   10596 C CG2 . ILE C 1 425 ? 20.099  31.987  -6.233  1.00 61.91  ? 425 ILE C CG2 1 
ATOM   10597 C CD1 . ILE C 1 425 ? 21.659  30.782  -8.572  1.00 52.05  ? 425 ILE C CD1 1 
ATOM   10598 N N   . THR C 1 426 ? 16.953  32.232  -9.456  1.00 45.42  ? 426 THR C N   1 
ATOM   10599 C CA  . THR C 1 426 ? 16.416  32.116  -10.791 1.00 44.59  ? 426 THR C CA  1 
ATOM   10600 C C   . THR C 1 426 ? 17.515  32.354  -11.830 1.00 55.69  ? 426 THR C C   1 
ATOM   10601 O O   . THR C 1 426 ? 18.570  32.924  -11.536 1.00 49.70  ? 426 THR C O   1 
ATOM   10602 C CB  . THR C 1 426 ? 15.222  33.048  -11.008 1.00 46.80  ? 426 THR C CB  1 
ATOM   10603 O OG1 . THR C 1 426 ? 15.726  34.361  -11.231 1.00 52.17  ? 426 THR C OG1 1 
ATOM   10604 C CG2 . THR C 1 426 ? 14.208  33.033  -9.875  1.00 47.06  ? 426 THR C CG2 1 
ATOM   10605 N N   . THR C 1 427 ? 17.217  31.909  -13.053 1.00 52.71  ? 427 THR C N   1 
ATOM   10606 C CA  . THR C 1 427 ? 18.053  32.107  -14.216 1.00 57.34  ? 427 THR C CA  1 
ATOM   10607 C C   . THR C 1 427 ? 17.948  33.573  -14.643 1.00 61.50  ? 427 THR C C   1 
ATOM   10608 O O   . THR C 1 427 ? 18.950  34.186  -15.010 1.00 68.07  ? 427 THR C O   1 
ATOM   10609 C CB  . THR C 1 427 ? 17.717  31.068  -15.303 1.00 54.02  ? 427 THR C CB  1 
ATOM   10610 O OG1 . THR C 1 427 ? 17.993  29.759  -14.796 1.00 52.24  ? 427 THR C OG1 1 
ATOM   10611 C CG2 . THR C 1 427 ? 18.538  31.224  -16.566 1.00 59.46  ? 427 THR C CG2 1 
ATOM   10612 N N   . ARG C 1 428 ? 16.746  34.148  -14.582 1.00 65.75  ? 428 ARG C N   1 
ATOM   10613 C CA  . ARG C 1 428 ? 16.586  35.573  -14.835 1.00 73.12  ? 428 ARG C CA  1 
ATOM   10614 C C   . ARG C 1 428 ? 17.655  36.316  -14.027 1.00 63.15  ? 428 ARG C C   1 
ATOM   10615 O O   . ARG C 1 428 ? 18.452  37.070  -14.567 1.00 65.49  ? 428 ARG C O   1 
ATOM   10616 C CB  . ARG C 1 428 ? 15.157  36.017  -14.485 1.00 82.96  ? 428 ARG C CB  1 
ATOM   10617 C CG  . ARG C 1 428 ? 14.940  37.527  -14.470 1.00 92.67  ? 428 ARG C CG  1 
ATOM   10618 C CD  . ARG C 1 428 ? 13.928  38.011  -13.432 1.00 99.45  ? 428 ARG C CD  1 
ATOM   10619 N NE  . ARG C 1 428 ? 14.270  37.834  -12.009 1.00 95.72  ? 428 ARG C NE  1 
ATOM   10620 C CZ  . ARG C 1 428 ? 15.040  38.649  -11.268 1.00 93.31  ? 428 ARG C CZ  1 
ATOM   10621 N NH1 . ARG C 1 428 ? 15.704  39.650  -11.825 1.00 80.43  ? 428 ARG C NH1 1 
ATOM   10622 N NH2 . ARG C 1 428 ? 15.164  38.451  -9.959  1.00 82.39  ? 428 ARG C NH2 1 
ATOM   10623 N N   . TRP C 1 429 ? 17.697  36.048  -12.723 1.00 62.25  ? 429 TRP C N   1 
ATOM   10624 C CA  . TRP C 1 429 ? 18.609  36.715  -11.817 1.00 57.41  ? 429 TRP C CA  1 
ATOM   10625 C C   . TRP C 1 429 ? 20.054  36.452  -12.225 1.00 68.15  ? 429 TRP C C   1 
ATOM   10626 O O   . TRP C 1 429 ? 20.876  37.366  -12.273 1.00 71.01  ? 429 TRP C O   1 
ATOM   10627 C CB  . TRP C 1 429 ? 18.371  36.232  -10.387 1.00 55.77  ? 429 TRP C CB  1 
ATOM   10628 C CG  . TRP C 1 429 ? 19.225  36.907  -9.366  1.00 59.07  ? 429 TRP C CG  1 
ATOM   10629 C CD1 . TRP C 1 429 ? 19.071  38.181  -8.901  1.00 62.14  ? 429 TRP C CD1 1 
ATOM   10630 C CD2 . TRP C 1 429 ? 20.373  36.374  -8.683  1.00 69.10  ? 429 TRP C CD2 1 
ATOM   10631 N NE1 . TRP C 1 429 ? 20.020  38.463  -7.957  1.00 63.17  ? 429 TRP C NE1 1 
ATOM   10632 C CE2 . TRP C 1 429 ? 20.843  37.386  -7.810  1.00 63.74  ? 429 TRP C CE2 1 
ATOM   10633 C CE3 . TRP C 1 429 ? 21.061  35.157  -8.724  1.00 67.44  ? 429 TRP C CE3 1 
ATOM   10634 C CZ2 . TRP C 1 429 ? 21.940  37.206  -6.974  1.00 62.17  ? 429 TRP C CZ2 1 
ATOM   10635 C CZ3 . TRP C 1 429 ? 22.155  34.981  -7.901  1.00 65.81  ? 429 TRP C CZ3 1 
ATOM   10636 C CH2 . TRP C 1 429 ? 22.587  35.991  -7.040  1.00 66.82  ? 429 TRP C CH2 1 
ATOM   10637 N N   . VAL C 1 430 ? 20.384  35.182  -12.453 1.00 57.58  ? 430 VAL C N   1 
ATOM   10638 C CA  . VAL C 1 430 ? 21.772  34.846  -12.690 1.00 60.02  ? 430 VAL C CA  1 
ATOM   10639 C C   . VAL C 1 430 ? 22.267  35.658  -13.888 1.00 58.48  ? 430 VAL C C   1 
ATOM   10640 O O   . VAL C 1 430 ? 23.296  36.300  -13.764 1.00 59.21  ? 430 VAL C O   1 
ATOM   10641 C CB  . VAL C 1 430 ? 21.968  33.328  -12.866 1.00 57.98  ? 430 VAL C CB  1 
ATOM   10642 C CG1 . VAL C 1 430 ? 23.253  32.988  -13.598 1.00 52.62  ? 430 VAL C CG1 1 
ATOM   10643 C CG2 . VAL C 1 430 ? 21.922  32.611  -11.528 1.00 58.88  ? 430 VAL C CG2 1 
ATOM   10644 N N   . LYS C 1 431 ? 21.509  35.649  -15.000 1.00 60.69  ? 431 LYS C N   1 
ATOM   10645 C CA  . LYS C 1 431 ? 21.856  36.328  -16.243 1.00 70.63  ? 431 LYS C CA  1 
ATOM   10646 C C   . LYS C 1 431 ? 22.147  37.813  -16.040 1.00 73.78  ? 431 LYS C C   1 
ATOM   10647 O O   . LYS C 1 431 ? 22.960  38.384  -16.757 1.00 82.52  ? 431 LYS C O   1 
ATOM   10648 C CB  . LYS C 1 431 ? 20.691  36.326  -17.236 1.00 70.38  ? 431 LYS C CB  1 
ATOM   10649 C CG  . LYS C 1 431 ? 20.549  35.098  -18.111 1.00 72.82  ? 431 LYS C CG  1 
ATOM   10650 C CD  . LYS C 1 431 ? 19.607  35.366  -19.253 1.00 78.57  ? 431 LYS C CD  1 
ATOM   10651 C CE  . LYS C 1 431 ? 18.668  34.216  -19.526 1.00 84.37  ? 431 LYS C CE  1 
ATOM   10652 N NZ  . LYS C 1 431 ? 17.580  34.616  -20.443 1.00 94.05  ? 431 LYS C NZ  1 
ATOM   10653 N N   . GLU C 1 432 ? 21.418  38.434  -15.112 1.00 73.26  ? 432 GLU C N   1 
ATOM   10654 C CA  . GLU C 1 432 ? 21.448  39.869  -14.949 1.00 78.75  ? 432 GLU C CA  1 
ATOM   10655 C C   . GLU C 1 432 ? 22.703  40.275  -14.184 1.00 71.17  ? 432 GLU C C   1 
ATOM   10656 O O   . GLU C 1 432 ? 23.312  41.284  -14.505 1.00 87.59  ? 432 GLU C O   1 
ATOM   10657 C CB  . GLU C 1 432 ? 20.185  40.353  -14.232 1.00 85.49  ? 432 GLU C CB  1 
ATOM   10658 C CG  . GLU C 1 432 ? 19.927  41.834  -14.453 1.00 99.92  ? 432 GLU C CG  1 
ATOM   10659 C CD  . GLU C 1 432 ? 19.249  42.555  -13.300 1.00 119.19 ? 432 GLU C CD  1 
ATOM   10660 O OE1 . GLU C 1 432 ? 19.458  43.784  -13.172 1.00 122.13 ? 432 GLU C OE1 1 
ATOM   10661 O OE2 . GLU C 1 432 ? 18.504  41.896  -12.544 1.00 130.94 ? 432 GLU C OE2 1 
ATOM   10662 N N   . VAL C 1 433 ? 23.091  39.497  -13.174 1.00 66.38  ? 433 VAL C N   1 
ATOM   10663 C CA  . VAL C 1 433 ? 24.153  39.908  -12.276 1.00 56.42  ? 433 VAL C CA  1 
ATOM   10664 C C   . VAL C 1 433 ? 25.430  39.119  -12.563 1.00 62.60  ? 433 VAL C C   1 
ATOM   10665 O O   . VAL C 1 433 ? 26.456  39.385  -11.943 1.00 63.13  ? 433 VAL C O   1 
ATOM   10666 C CB  . VAL C 1 433 ? 23.723  39.774  -10.800 1.00 65.30  ? 433 VAL C CB  1 
ATOM   10667 C CG1 . VAL C 1 433 ? 22.416  40.503  -10.526 1.00 63.39  ? 433 VAL C CG1 1 
ATOM   10668 C CG2 . VAL C 1 433 ? 23.617  38.329  -10.336 1.00 67.35  ? 433 VAL C CG2 1 
ATOM   10669 N N   . ALA C 1 434 ? 25.375  38.141  -13.475 1.00 62.35  ? 434 ALA C N   1 
ATOM   10670 C CA  . ALA C 1 434 ? 26.457  37.173  -13.598 1.00 69.91  ? 434 ALA C CA  1 
ATOM   10671 C C   . ALA C 1 434 ? 27.758  37.882  -13.978 1.00 78.98  ? 434 ALA C C   1 
ATOM   10672 O O   . ALA C 1 434 ? 28.776  37.702  -13.305 1.00 60.27  ? 434 ALA C O   1 
ATOM   10673 C CB  . ALA C 1 434 ? 26.108  36.110  -14.615 1.00 71.02  ? 434 ALA C CB  1 
ATOM   10674 N N   . GLU C 1 435 ? 27.697  38.699  -15.043 1.00 88.74  ? 435 GLU C N   1 
ATOM   10675 C CA  . GLU C 1 435 ? 28.855  39.434  -15.538 1.00 98.03  ? 435 GLU C CA  1 
ATOM   10676 C C   . GLU C 1 435 ? 29.561  40.165  -14.398 1.00 85.19  ? 435 GLU C C   1 
ATOM   10677 O O   . GLU C 1 435 ? 30.773  40.062  -14.306 1.00 78.81  ? 435 GLU C O   1 
ATOM   10678 C CB  . GLU C 1 435 ? 28.462  40.408  -16.654 1.00 108.58 ? 435 GLU C CB  1 
ATOM   10679 C CG  . GLU C 1 435 ? 28.366  39.742  -18.025 1.00 117.53 ? 435 GLU C CG  1 
ATOM   10680 C CD  . GLU C 1 435 ? 27.818  40.567  -19.187 1.00 111.52 ? 435 GLU C CD  1 
ATOM   10681 O OE1 . GLU C 1 435 ? 28.632  41.129  -19.959 1.00 103.76 ? 435 GLU C OE1 1 
ATOM   10682 O OE2 . GLU C 1 435 ? 26.579  40.594  -19.366 1.00 83.92  ? 435 GLU C OE2 1 
ATOM   10683 N N   . SER C 1 436 ? 28.799  40.818  -13.506 1.00 74.52  ? 436 SER C N   1 
ATOM   10684 C CA  . SER C 1 436 ? 29.338  41.714  -12.489 1.00 79.63  ? 436 SER C CA  1 
ATOM   10685 C C   . SER C 1 436 ? 29.754  41.015  -11.191 1.00 79.66  ? 436 SER C C   1 
ATOM   10686 O O   . SER C 1 436 ? 30.105  41.697  -10.227 1.00 75.62  ? 436 SER C O   1 
ATOM   10687 C CB  . SER C 1 436 ? 28.338  42.800  -12.173 1.00 85.10  ? 436 SER C CB  1 
ATOM   10688 O OG  . SER C 1 436 ? 27.142  42.239  -11.655 1.00 90.76  ? 436 SER C OG  1 
ATOM   10689 N N   . LEU C 1 437 ? 29.734  39.674  -11.151 1.00 73.54  ? 437 LEU C N   1 
ATOM   10690 C CA  . LEU C 1 437 ? 30.070  38.954  -9.930  1.00 66.63  ? 437 LEU C CA  1 
ATOM   10691 C C   . LEU C 1 437 ? 31.578  38.709  -9.834  1.00 67.47  ? 437 LEU C C   1 
ATOM   10692 O O   . LEU C 1 437 ? 32.251  38.489  -10.843 1.00 72.35  ? 437 LEU C O   1 
ATOM   10693 C CB  . LEU C 1 437 ? 29.305  37.627  -9.886  1.00 70.40  ? 437 LEU C CB  1 
ATOM   10694 C CG  . LEU C 1 437 ? 27.802  37.705  -9.600  1.00 74.62  ? 437 LEU C CG  1 
ATOM   10695 C CD1 . LEU C 1 437 ? 27.186  36.323  -9.693  1.00 69.88  ? 437 LEU C CD1 1 
ATOM   10696 C CD2 . LEU C 1 437 ? 27.514  38.336  -8.237  1.00 68.69  ? 437 LEU C CD2 1 
ATOM   10697 N N   . PRO C 1 438 ? 32.150  38.717  -8.605  1.00 58.00  ? 438 PRO C N   1 
ATOM   10698 C CA  . PRO C 1 438 ? 33.548  38.331  -8.400  1.00 58.96  ? 438 PRO C CA  1 
ATOM   10699 C C   . PRO C 1 438 ? 33.817  36.843  -8.631  1.00 66.76  ? 438 PRO C C   1 
ATOM   10700 O O   . PRO C 1 438 ? 32.926  36.017  -8.439  1.00 65.00  ? 438 PRO C O   1 
ATOM   10701 C CB  . PRO C 1 438 ? 33.822  38.657  -6.920  1.00 56.95  ? 438 PRO C CB  1 
ATOM   10702 C CG  . PRO C 1 438 ? 32.438  38.694  -6.259  1.00 60.94  ? 438 PRO C CG  1 
ATOM   10703 C CD  . PRO C 1 438 ? 31.464  39.099  -7.352  1.00 54.89  ? 438 PRO C CD  1 
ATOM   10704 N N   . VAL C 1 439 ? 35.072  36.511  -8.974  1.00 60.34  ? 439 VAL C N   1 
ATOM   10705 C CA  . VAL C 1 439 ? 35.486  35.142  -9.262  1.00 57.62  ? 439 VAL C CA  1 
ATOM   10706 C C   . VAL C 1 439 ? 35.957  34.489  -7.970  1.00 64.73  ? 439 VAL C C   1 
ATOM   10707 O O   . VAL C 1 439 ? 36.614  35.128  -7.156  1.00 72.02  ? 439 VAL C O   1 
ATOM   10708 C CB  . VAL C 1 439 ? 36.579  35.080  -10.348 1.00 55.79  ? 439 VAL C CB  1 
ATOM   10709 C CG1 . VAL C 1 439 ? 37.196  33.695  -10.468 1.00 59.72  ? 439 VAL C CG1 1 
ATOM   10710 C CG2 . VAL C 1 439 ? 36.061  35.540  -11.696 1.00 53.41  ? 439 VAL C CG2 1 
ATOM   10711 N N   . ALA C 1 440 ? 35.608  33.210  -7.787  1.00 68.93  ? 440 ALA C N   1 
ATOM   10712 C CA  . ALA C 1 440 ? 35.843  32.544  -6.518  1.00 75.46  ? 440 ALA C CA  1 
ATOM   10713 C C   . ALA C 1 440 ? 37.340  32.302  -6.345  1.00 78.58  ? 440 ALA C C   1 
ATOM   10714 O O   . ALA C 1 440 ? 38.004  31.915  -7.300  1.00 82.22  ? 440 ALA C O   1 
ATOM   10715 C CB  . ALA C 1 440 ? 35.058  31.252  -6.457  1.00 73.30  ? 440 ALA C CB  1 
ATOM   10716 N N   . GLY C 1 441 ? 37.845  32.542  -5.126  1.00 83.72  ? 441 GLY C N   1 
ATOM   10717 C CA  . GLY C 1 441 ? 39.218  32.235  -4.758  1.00 91.09  ? 441 GLY C CA  1 
ATOM   10718 C C   . GLY C 1 441 ? 40.175  33.417  -4.936  1.00 98.25  ? 441 GLY C C   1 
ATOM   10719 O O   . GLY C 1 441 ? 41.291  33.377  -4.412  1.00 95.90  ? 441 GLY C O   1 
ATOM   10720 N N   . SER C 1 442 ? 39.730  34.472  -5.645  1.00 95.46  ? 442 SER C N   1 
ATOM   10721 C CA  . SER C 1 442 ? 40.616  35.542  -6.089  1.00 107.45 ? 442 SER C CA  1 
ATOM   10722 C C   . SER C 1 442 ? 41.097  36.394  -4.901  1.00 111.28 ? 442 SER C C   1 
ATOM   10723 O O   . SER C 1 442 ? 40.275  37.149  -4.339  1.00 96.50  ? 442 SER C O   1 
ATOM   10724 C CB  . SER C 1 442 ? 39.980  36.384  -7.193  1.00 103.45 ? 442 SER C CB  1 
ATOM   10725 O OG  . SER C 1 442 ? 38.926  37.217  -6.724  1.00 82.05  ? 442 SER C OG  1 
HETATM 10726 N N1A . COA D 2 .   ? 9.447   -24.901 -43.152 1.00 109.64 ? 501 COA A N1A 1 
HETATM 10727 C C2A . COA D 2 .   ? 10.254  -25.966 -43.049 1.00 110.62 ? 501 COA A C2A 1 
HETATM 10728 N N3A . COA D 2 .   ? 9.949   -27.262 -43.086 1.00 125.55 ? 501 COA A N3A 1 
HETATM 10729 C C4A . COA D 2 .   ? 8.625   -27.438 -43.255 1.00 141.21 ? 501 COA A C4A 1 
HETATM 10730 C C5A . COA D 2 .   ? 7.672   -26.448 -43.379 1.00 139.91 ? 501 COA A C5A 1 
HETATM 10731 C C6A . COA D 2 .   ? 8.117   -25.114 -43.324 1.00 129.53 ? 501 COA A C6A 1 
HETATM 10732 N N6A . COA D 2 .   ? 7.301   -24.072 -43.429 1.00 130.21 ? 501 COA A N6A 1 
HETATM 10733 N N7A . COA D 2 .   ? 6.408   -27.004 -43.543 1.00 143.78 ? 501 COA A N7A 1 
HETATM 10734 C C8A . COA D 2 .   ? 6.613   -28.302 -43.511 1.00 148.71 ? 501 COA A C8A 1 
HETATM 10735 N N9A . COA D 2 .   ? 7.946   -28.629 -43.344 1.00 145.31 ? 501 COA A N9A 1 
HETATM 10736 C C1B . COA D 2 .   ? 8.539   -29.982 -43.263 1.00 127.69 ? 501 COA A C1B 1 
HETATM 10737 C C2B . COA D 2 .   ? 8.388   -30.667 -41.913 1.00 122.96 ? 501 COA A C2B 1 
HETATM 10738 O O2B . COA D 2 .   ? 9.302   -30.136 -40.980 1.00 117.31 ? 501 COA A O2B 1 
HETATM 10739 C C3B . COA D 2 .   ? 8.635   -32.132 -42.298 1.00 119.69 ? 501 COA A C3B 1 
HETATM 10740 O O3B . COA D 2 .   ? 10.024  -32.469 -42.332 1.00 117.00 ? 501 COA A O3B 1 
HETATM 10741 P P3B . COA D 2 .   ? 10.494  -33.535 -41.195 1.00 118.28 ? 501 COA A P3B 1 
HETATM 10742 O O7A . COA D 2 .   ? 9.862   -33.200 -39.838 1.00 111.52 ? 501 COA A O7A 1 
HETATM 10743 O O8A . COA D 2 .   ? 11.998  -33.336 -41.192 1.00 88.06  ? 501 COA A O8A 1 
HETATM 10744 O O9A . COA D 2 .   ? 10.089  -34.927 -41.660 1.00 110.00 ? 501 COA A O9A 1 
HETATM 10745 C C4B . COA D 2 .   ? 8.045   -32.220 -43.705 1.00 114.21 ? 501 COA A C4B 1 
HETATM 10746 O O4B . COA D 2 .   ? 7.870   -30.848 -44.151 1.00 125.28 ? 501 COA A O4B 1 
HETATM 10747 C C5B . COA D 2 .   ? 6.729   -32.955 -43.794 1.00 118.35 ? 501 COA A C5B 1 
HETATM 10748 O O5B . COA D 2 .   ? 5.816   -32.455 -42.777 1.00 111.76 ? 501 COA A O5B 1 
HETATM 10749 P P1A . COA D 2 .   ? 4.333   -31.964 -43.161 1.00 98.85  ? 501 COA A P1A 1 
HETATM 10750 O O1A . COA D 2 .   ? 3.423   -33.137 -43.360 1.00 88.37  ? 501 COA A O1A 1 
HETATM 10751 O O2A . COA D 2 .   ? 4.406   -30.994 -44.298 1.00 96.13  ? 501 COA A O2A 1 
HETATM 10752 O O3A . COA D 2 .   ? 3.981   -31.179 -41.797 1.00 101.43 ? 501 COA A O3A 1 
HETATM 10753 P P2A . COA D 2 .   ? 3.552   -31.540 -40.284 1.00 102.14 ? 501 COA A P2A 1 
HETATM 10754 O O4A . COA D 2 .   ? 2.123   -31.988 -40.311 1.00 96.60  ? 501 COA A O4A 1 
HETATM 10755 O O5A . COA D 2 .   ? 4.606   -32.384 -39.628 1.00 75.48  ? 501 COA A O5A 1 
HETATM 10756 O O6A . COA D 2 .   ? 3.592   -30.090 -39.591 1.00 106.14 ? 501 COA A O6A 1 
HETATM 10757 C CBP . COA D 2 .   ? 2.927   -27.762 -39.303 1.00 100.68 ? 501 COA A CBP 1 
HETATM 10758 C CCP . COA D 2 .   ? 2.500   -29.143 -39.806 1.00 102.08 ? 501 COA A CCP 1 
HETATM 10759 C CDP . COA D 2 .   ? 1.721   -26.815 -39.404 1.00 96.00  ? 501 COA A CDP 1 
HETATM 10760 C CEP . COA D 2 .   ? 3.341   -27.887 -37.825 1.00 87.61  ? 501 COA A CEP 1 
HETATM 10761 C CAP . COA D 2 .   ? 4.106   -27.223 -40.148 1.00 103.00 ? 501 COA A CAP 1 
HETATM 10762 O OAP . COA D 2 .   ? 3.659   -26.906 -41.486 1.00 79.03  ? 501 COA A OAP 1 
HETATM 10763 C C9P . COA D 2 .   ? 4.856   -26.033 -39.531 1.00 101.44 ? 501 COA A C9P 1 
HETATM 10764 O O9P . COA D 2 .   ? 5.753   -26.254 -38.715 1.00 88.85  ? 501 COA A O9P 1 
HETATM 10765 N N8P . COA D 2 .   ? 4.508   -24.801 -39.910 1.00 95.30  ? 501 COA A N8P 1 
HETATM 10766 C C7P . COA D 2 .   ? 5.139   -23.575 -39.423 1.00 91.64  ? 501 COA A C7P 1 
HETATM 10767 C C6P . COA D 2 .   ? 4.452   -22.983 -38.193 1.00 89.81  ? 501 COA A C6P 1 
HETATM 10768 C C5P . COA D 2 .   ? 3.024   -22.552 -38.465 1.00 89.39  ? 501 COA A C5P 1 
HETATM 10769 O O5P . COA D 2 .   ? 2.767   -21.737 -39.356 1.00 72.34  ? 501 COA A O5P 1 
HETATM 10770 N N4P . COA D 2 .   ? 2.063   -23.114 -37.709 1.00 91.05  ? 501 COA A N4P 1 
HETATM 10771 C C3P . COA D 2 .   ? 0.642   -22.806 -37.839 1.00 102.25 ? 501 COA A C3P 1 
HETATM 10772 C C2P . COA D 2 .   ? -0.240  -24.036 -37.923 1.00 109.38 ? 501 COA A C2P 1 
HETATM 10773 S S1P . COA D 2 .   ? -2.003  -23.637 -37.752 1.00 142.53 ? 501 COA A S1P 1 
HETATM 10774 O O1  . OAA E 3 .   ? -6.915  -27.103 -37.404 1.00 63.49  ? 502 OAA A O1  1 
HETATM 10775 O O2  . OAA E 3 .   ? -5.061  -28.194 -36.970 1.00 63.48  ? 502 OAA A O2  1 
HETATM 10776 O O4  . OAA E 3 .   ? -7.537  -23.164 -36.612 1.00 68.83  ? 502 OAA A O4  1 
HETATM 10777 O O5  . OAA E 3 .   ? -7.251  -24.852 -35.252 1.00 57.80  ? 502 OAA A O5  1 
HETATM 10778 O O3  . OAA E 3 .   ? -5.561  -24.075 -38.016 1.00 71.23  ? 502 OAA A O3  1 
HETATM 10779 C C1  . OAA E 3 .   ? -5.735  -27.150 -37.013 1.00 64.85  ? 502 OAA A C1  1 
HETATM 10780 C C2  . OAA E 3 .   ? -5.090  -25.851 -36.538 1.00 74.51  ? 502 OAA A C2  1 
HETATM 10781 C C3  . OAA E 3 .   ? -5.887  -24.634 -36.969 1.00 75.38  ? 502 OAA A C3  1 
HETATM 10782 C C4  . OAA E 3 .   ? -6.916  -24.196 -36.252 1.00 71.43  ? 502 OAA A C4  1 
HETATM 10783 O O1  . OAA F 3 .   ? -10.944 -47.040 -18.835 1.00 66.52  ? 501 OAA B O1  1 
HETATM 10784 O O2  . OAA F 3 .   ? -12.676 -45.974 -17.933 1.00 79.70  ? 501 OAA B O2  1 
HETATM 10785 O O4  . OAA F 3 .   ? -11.025 -47.051 -13.570 1.00 94.03  ? 501 OAA B O4  1 
HETATM 10786 O O5  . OAA F 3 .   ? -12.503 -45.513 -13.319 1.00 95.13  ? 501 OAA B O5  1 
HETATM 10787 O O3  . OAA F 3 .   ? -11.848 -44.629 -15.564 1.00 89.39  ? 501 OAA B O3  1 
HETATM 10788 C C1  . OAA F 3 .   ? -11.574 -46.550 -17.828 1.00 82.11  ? 501 OAA B C1  1 
HETATM 10789 C C2  . OAA F 3 .   ? -10.948 -46.649 -16.422 1.00 88.39  ? 501 OAA B C2  1 
HETATM 10790 C C3  . OAA F 3 .   ? -11.507 -45.770 -15.293 1.00 92.94  ? 501 OAA B C3  1 
HETATM 10791 C C4  . OAA F 3 .   ? -11.707 -46.146 -14.033 1.00 95.28  ? 501 OAA B C4  1 
HETATM 10792 N N1A . COA G 2 .   ? 33.822  5.662   -17.658 1.00 53.47  ? 501 COA C N1A 1 
HETATM 10793 C C2A . COA G 2 .   ? 33.821  6.651   -18.565 1.00 64.68  ? 501 COA C C2A 1 
HETATM 10794 N N3A . COA G 2 .   ? 33.852  7.971   -18.387 1.00 52.95  ? 501 COA C N3A 1 
HETATM 10795 C C4A . COA G 2 .   ? 33.920  8.269   -17.082 1.00 56.07  ? 501 COA C C4A 1 
HETATM 10796 C C5A . COA G 2 .   ? 33.926  7.373   -16.036 1.00 59.07  ? 501 COA C C5A 1 
HETATM 10797 C C6A . COA G 2 .   ? 33.871  6.004   -16.348 1.00 57.98  ? 501 COA C C6A 1 
HETATM 10798 N N6A . COA G 2 .   ? 33.850  5.051   -15.427 1.00 59.43  ? 501 COA C N6A 1 
HETATM 10799 N N7A . COA G 2 .   ? 33.984  8.049   -14.830 1.00 64.80  ? 501 COA C N7A 1 
HETATM 10800 C C8A . COA G 2 .   ? 33.983  9.319   -15.161 1.00 61.56  ? 501 COA C C8A 1 
HETATM 10801 N N9A . COA G 2 .   ? 33.954  9.515   -16.513 1.00 61.11  ? 501 COA C N9A 1 
HETATM 10802 C C1B . COA G 2 .   ? 33.981  10.817  -17.227 1.00 65.54  ? 501 COA C C1B 1 
HETATM 10803 C C2B . COA G 2 .   ? 32.689  11.612  -17.086 1.00 67.64  ? 501 COA C C2B 1 
HETATM 10804 O O2B . COA G 2 .   ? 31.710  11.113  -17.968 1.00 76.41  ? 501 COA C O2B 1 
HETATM 10805 C C3B . COA G 2 .   ? 33.182  13.028  -17.404 1.00 69.42  ? 501 COA C C3B 1 
HETATM 10806 O O3B . COA G 2 .   ? 33.256  13.246  -18.816 1.00 84.02  ? 501 COA C O3B 1 
HETATM 10807 P P3B . COA G 2 .   ? 32.236  14.345  -19.403 1.00 81.54  ? 501 COA C P3B 1 
HETATM 10808 O O7A . COA G 2 .   ? 30.943  14.333  -18.584 1.00 78.47  ? 501 COA C O7A 1 
HETATM 10809 O O8A . COA G 2 .   ? 32.000  13.970  -20.847 1.00 84.67  ? 501 COA C O8A 1 
HETATM 10810 O O9A . COA G 2 .   ? 33.026  15.618  -19.248 1.00 82.72  ? 501 COA C O9A 1 
HETATM 10811 C C4B . COA G 2 .   ? 34.596  13.046  -16.817 1.00 66.77  ? 501 COA C C4B 1 
HETATM 10812 O O4B . COA G 2 .   ? 34.987  11.648  -16.682 1.00 62.49  ? 501 COA C O4B 1 
HETATM 10813 C C5B . COA G 2 .   ? 34.758  13.785  -15.503 1.00 63.77  ? 501 COA C C5B 1 
HETATM 10814 O O5B . COA G 2 .   ? 33.720  13.394  -14.559 1.00 62.80  ? 501 COA C O5B 1 
HETATM 10815 P P1A . COA G 2 .   ? 34.107  12.889  -13.077 1.00 64.89  ? 501 COA C P1A 1 
HETATM 10816 O O1A . COA G 2 .   ? 34.277  14.042  -12.136 1.00 59.60  ? 501 COA C O1A 1 
HETATM 10817 O O2A . COA G 2 .   ? 35.293  11.992  -13.156 1.00 57.42  ? 501 COA C O2A 1 
HETATM 10818 O O3A . COA G 2 .   ? 32.742  12.125  -12.730 1.00 69.93  ? 501 COA C O3A 1 
HETATM 10819 P P2A . COA G 2 .   ? 31.390  12.587  -11.974 1.00 66.64  ? 501 COA C P2A 1 
HETATM 10820 O O4A . COA G 2 .   ? 31.753  12.976  -10.569 1.00 69.15  ? 501 COA C O4A 1 
HETATM 10821 O O5A . COA G 2 .   ? 30.532  13.402  -12.885 1.00 62.42  ? 501 COA C O5A 1 
HETATM 10822 O O6A . COA G 2 .   ? 30.539  11.224  -11.939 1.00 68.26  ? 501 COA C O6A 1 
HETATM 10823 C CBP . COA G 2 .   ? 30.298  8.861   -11.583 1.00 61.45  ? 501 COA C CBP 1 
HETATM 10824 C CCP . COA G 2 .   ? 30.883  10.159  -11.010 1.00 66.69  ? 501 COA C CCP 1 
HETATM 10825 C CDP . COA G 2 .   ? 30.355  7.780   -10.495 1.00 52.74  ? 501 COA C CDP 1 
HETATM 10826 C CEP . COA G 2 .   ? 28.824  9.100   -11.966 1.00 57.08  ? 501 COA C CEP 1 
HETATM 10827 C CAP . COA G 2 .   ? 31.076  8.371   -12.817 1.00 57.07  ? 501 COA C CAP 1 
HETATM 10828 O OAP . COA G 2 .   ? 32.414  8.018   -12.416 1.00 52.78  ? 501 COA C OAP 1 
HETATM 10829 C C9P . COA G 2 .   ? 30.379  7.199   -13.510 1.00 49.47  ? 501 COA C C9P 1 
HETATM 10830 O O9P . COA G 2 .   ? 29.503  7.429   -14.337 1.00 52.71  ? 501 COA C O9P 1 
HETATM 10831 N N8P . COA G 2 .   ? 30.726  5.966   -13.151 1.00 52.65  ? 501 COA C N8P 1 
HETATM 10832 C C7P . COA G 2 .   ? 30.089  4.742   -13.638 1.00 53.79  ? 501 COA C C7P 1 
HETATM 10833 C C6P . COA G 2 .   ? 28.882  4.282   -12.786 1.00 55.03  ? 501 COA C C6P 1 
HETATM 10834 C C5P . COA G 2 .   ? 29.232  3.877   -11.361 1.00 58.11  ? 501 COA C C5P 1 
HETATM 10835 O O5P . COA G 2 .   ? 30.144  3.085   -11.126 1.00 57.33  ? 501 COA C O5P 1 
HETATM 10836 N N4P . COA G 2 .   ? 28.513  4.430   -10.372 1.00 61.08  ? 501 COA C N4P 1 
HETATM 10837 C C3P . COA G 2 .   ? 28.758  4.216   -8.953  1.00 55.09  ? 501 COA C C3P 1 
HETATM 10838 C C2P . COA G 2 .   ? 29.259  5.472   -8.277  1.00 64.02  ? 501 COA C C2P 1 
HETATM 10839 S S1P . COA G 2 .   ? 28.043  6.816   -8.127  1.00 85.91  ? 501 COA C S1P 1 
HETATM 10840 C C1  . CIT H 4 .   ? 27.979  8.404   -2.849  1.00 56.98  ? 502 CIT C C1  1 
HETATM 10841 O O1  . CIT H 4 .   ? 27.752  9.563   -3.311  1.00 54.85  ? 502 CIT C O1  1 
HETATM 10842 O O2  . CIT H 4 .   ? 28.604  8.186   -1.778  1.00 57.16  ? 502 CIT C O2  1 
HETATM 10843 C C2  . CIT H 4 .   ? 27.417  7.219   -3.619  1.00 62.75  ? 502 CIT C C2  1 
HETATM 10844 C C3  . CIT H 4 .   ? 27.720  5.811   -3.069  1.00 76.22  ? 502 CIT C C3  1 
HETATM 10845 O O7  . CIT H 4 .   ? 29.134  5.626   -3.007  1.00 62.05  ? 502 CIT C O7  1 
HETATM 10846 C C4  . CIT H 4 .   ? 27.051  4.757   -3.967  1.00 77.22  ? 502 CIT C C4  1 
HETATM 10847 C C5  . CIT H 4 .   ? 27.760  4.418   -5.266  1.00 89.88  ? 502 CIT C C5  1 
HETATM 10848 O O3  . CIT H 4 .   ? 27.005  4.156   -6.223  1.00 90.52  ? 502 CIT C O3  1 
HETATM 10849 O O4  . CIT H 4 .   ? 29.046  4.396   -5.319  1.00 73.13  ? 502 CIT C O4  1 
HETATM 10850 C C6  . CIT H 4 .   ? 27.078  5.604   -1.671  1.00 72.29  ? 502 CIT C C6  1 
HETATM 10851 O O5  . CIT H 4 .   ? 26.098  6.319   -1.369  1.00 61.34  ? 502 CIT C O5  1 
HETATM 10852 O O6  . CIT H 4 .   ? 27.520  4.644   -0.996  1.00 68.04  ? 502 CIT C O6  1 
HETATM 10853 O O   . HOH I 5 .   ? -36.087 -31.130 -24.254 1.00 62.82  ? 601 HOH A O   1 
HETATM 10854 O O   . HOH I 5 .   ? -33.608 -28.657 -19.155 1.00 62.65  ? 602 HOH A O   1 
HETATM 10855 O O   . HOH I 5 .   ? -13.032 2.166   -25.130 1.00 37.11  ? 603 HOH A O   1 
HETATM 10856 O O   . HOH I 5 .   ? -14.673 -8.369  -4.506  1.00 41.42  ? 604 HOH A O   1 
HETATM 10857 O O   . HOH I 5 .   ? -3.417  -48.812 -33.781 1.00 46.81  ? 605 HOH A O   1 
HETATM 10858 O O   . HOH I 5 .   ? -20.022 -25.438 -8.939  1.00 34.15  ? 606 HOH A O   1 
HETATM 10859 O O   . HOH I 5 .   ? -11.089 -21.189 -37.981 1.00 41.82  ? 607 HOH A O   1 
HETATM 10860 O O   . HOH I 5 .   ? -26.993 -35.590 -24.416 1.00 46.29  ? 608 HOH A O   1 
HETATM 10861 O O   . HOH I 5 .   ? -12.568 -5.490  -49.609 1.00 62.74  ? 609 HOH A O   1 
HETATM 10862 O O   . HOH I 5 .   ? -3.083  -10.476 -6.970  1.00 39.20  ? 610 HOH A O   1 
HETATM 10863 O O   . HOH I 5 .   ? -16.079 -32.309 -39.660 1.00 44.42  ? 611 HOH A O   1 
HETATM 10864 O O   . HOH I 5 .   ? -16.237 3.484   -33.960 1.00 51.54  ? 612 HOH A O   1 
HETATM 10865 O O   . HOH I 5 .   ? -19.720 -5.281  -40.221 1.00 50.94  ? 613 HOH A O   1 
HETATM 10866 O O   . HOH I 5 .   ? -12.230 -48.527 -25.681 1.00 48.04  ? 614 HOH A O   1 
HETATM 10867 O O   . HOH I 5 .   ? -26.378 -30.646 -37.260 1.00 53.91  ? 615 HOH A O   1 
HETATM 10868 O O   . HOH I 5 .   ? -4.491  -22.092 -19.598 1.00 33.09  ? 616 HOH A O   1 
HETATM 10869 O O   . HOH I 5 .   ? -32.062 -23.029 -23.619 1.00 52.80  ? 617 HOH A O   1 
HETATM 10870 O O   . HOH I 5 .   ? -19.646 -8.945  -33.246 1.00 44.03  ? 618 HOH A O   1 
HETATM 10871 O O   . HOH I 5 .   ? -15.720 -40.317 -31.403 1.00 38.08  ? 619 HOH A O   1 
HETATM 10872 O O   . HOH I 5 .   ? -3.082  -12.978 -4.764  1.00 41.82  ? 620 HOH A O   1 
HETATM 10873 O O   . HOH I 5 .   ? -18.744 -34.735 -26.793 1.00 41.19  ? 621 HOH A O   1 
HETATM 10874 O O   . HOH I 5 .   ? 11.366  -10.434 -33.865 1.00 46.86  ? 622 HOH A O   1 
HETATM 10875 O O   . HOH I 5 .   ? -18.516 -38.818 -28.513 1.00 41.47  ? 623 HOH A O   1 
HETATM 10876 O O   . HOH I 5 .   ? -23.114 -26.388 -20.296 1.00 36.62  ? 624 HOH A O   1 
HETATM 10877 O O   . HOH I 5 .   ? -14.284 -10.605 -2.400  1.00 40.43  ? 625 HOH A O   1 
HETATM 10878 O O   . HOH I 5 .   ? -0.926  -11.240 -47.969 1.00 49.65  ? 626 HOH A O   1 
HETATM 10879 O O   . HOH I 5 .   ? -29.902 -35.989 -14.773 1.00 49.82  ? 627 HOH A O   1 
HETATM 10880 O O   . HOH I 5 .   ? -3.682  -5.267  -10.756 1.00 36.86  ? 628 HOH A O   1 
HETATM 10881 O O   . HOH I 5 .   ? -21.894 -38.744 -23.562 1.00 35.54  ? 629 HOH A O   1 
HETATM 10882 O O   . HOH I 5 .   ? -14.773 -43.608 -39.024 1.00 52.89  ? 630 HOH A O   1 
HETATM 10883 O O   . HOH I 5 .   ? -25.568 -17.277 -6.539  1.00 41.34  ? 631 HOH A O   1 
HETATM 10884 O O   . HOH I 5 .   ? -19.073 -27.608 -44.128 1.00 53.55  ? 632 HOH A O   1 
HETATM 10885 O O   . HOH I 5 .   ? -16.195 -20.664 -8.539  1.00 36.11  ? 633 HOH A O   1 
HETATM 10886 O O   . HOH I 5 .   ? 22.908  -15.559 -48.718 1.00 51.81  ? 634 HOH A O   1 
HETATM 10887 O O   . HOH I 5 .   ? 2.318   -10.779 -21.455 1.00 51.32  ? 635 HOH A O   1 
HETATM 10888 O O   . HOH I 5 .   ? -19.770 -28.890 -22.266 1.00 40.84  ? 636 HOH A O   1 
HETATM 10889 O O   . HOH I 5 .   ? 3.151   -11.111 -18.533 1.00 57.25  ? 637 HOH A O   1 
HETATM 10890 O O   . HOH I 5 .   ? -23.821 -12.372 -39.560 1.00 39.52  ? 638 HOH A O   1 
HETATM 10891 O O   . HOH I 5 .   ? -16.521 2.177   -18.569 1.00 50.67  ? 639 HOH A O   1 
HETATM 10892 O O   . HOH I 5 .   ? 4.995   -51.478 -22.930 1.00 48.47  ? 640 HOH A O   1 
HETATM 10893 O O   . HOH I 5 .   ? -20.745 -10.426 -44.574 1.00 54.45  ? 641 HOH A O   1 
HETATM 10894 O O   . HOH I 5 .   ? -6.266  -11.134 -13.825 1.00 37.05  ? 642 HOH A O   1 
HETATM 10895 O O   . HOH I 5 .   ? -25.034 -41.397 -25.113 1.00 39.24  ? 643 HOH A O   1 
HETATM 10896 O O   . HOH I 5 .   ? -25.431 -23.987 -11.037 1.00 45.14  ? 644 HOH A O   1 
HETATM 10897 O O   . HOH I 5 .   ? -37.749 -29.502 -28.914 1.00 57.88  ? 645 HOH A O   1 
HETATM 10898 O O   . HOH I 5 .   ? -11.189 1.106   -13.513 1.00 41.00  ? 646 HOH A O   1 
HETATM 10899 O O   . HOH I 5 .   ? -4.634  -29.191 -33.327 1.00 51.79  ? 647 HOH A O   1 
HETATM 10900 O O   . HOH I 5 .   ? -11.692 -16.129 -48.610 1.00 59.84  ? 648 HOH A O   1 
HETATM 10901 O O   . HOH I 5 .   ? 12.971  -50.649 -26.550 1.00 64.06  ? 649 HOH A O   1 
HETATM 10902 O O   . HOH I 5 .   ? 1.735   -8.296  -17.418 1.00 57.28  ? 650 HOH A O   1 
HETATM 10903 O O   . HOH I 5 .   ? 3.084   -10.175 -24.691 1.00 42.48  ? 651 HOH A O   1 
HETATM 10904 O O   . HOH I 5 .   ? -7.626  -47.618 -45.342 1.00 56.52  ? 652 HOH A O   1 
HETATM 10905 O O   . HOH I 5 .   ? -21.980 -42.663 -22.840 1.00 36.65  ? 653 HOH A O   1 
HETATM 10906 O O   . HOH I 5 .   ? 11.994  -62.272 -36.959 1.00 61.63  ? 654 HOH A O   1 
HETATM 10907 O O   . HOH I 5 .   ? -4.157  -23.813 -34.615 1.00 69.01  ? 655 HOH A O   1 
HETATM 10908 O O   . HOH I 5 .   ? -25.322 -29.079 -42.474 1.00 49.49  ? 656 HOH A O   1 
HETATM 10909 O O   . HOH I 5 .   ? -1.439  -16.081 -31.164 1.00 56.71  ? 657 HOH A O   1 
HETATM 10910 O O   . HOH I 5 .   ? 11.232  0.015   -46.592 1.00 64.68  ? 658 HOH A O   1 
HETATM 10911 O O   . HOH I 5 .   ? -10.830 -3.504  -10.878 1.00 65.56  ? 659 HOH A O   1 
HETATM 10912 O O   . HOH I 5 .   ? -13.150 -13.348 -48.686 1.00 45.98  ? 660 HOH A O   1 
HETATM 10913 O O   . HOH I 5 .   ? 5.867   -15.780 -29.621 1.00 64.65  ? 661 HOH A O   1 
HETATM 10914 O O   . HOH I 5 .   ? -33.143 -7.743  -31.629 1.00 56.38  ? 662 HOH A O   1 
HETATM 10915 O O   . HOH I 5 .   ? 13.279  -8.468  -34.671 1.00 57.81  ? 663 HOH A O   1 
HETATM 10916 O O   . HOH J 5 .   ? 2.147   -24.651 -20.884 1.00 35.05  ? 601 HOH B O   1 
HETATM 10917 O O   . HOH J 5 .   ? -2.340  -51.804 7.762   1.00 57.38  ? 602 HOH B O   1 
HETATM 10918 O O   . HOH J 5 .   ? 2.228   -42.616 0.750   1.00 53.19  ? 603 HOH B O   1 
HETATM 10919 O O   . HOH J 5 .   ? -6.870  -33.330 -31.072 1.00 46.65  ? 604 HOH B O   1 
HETATM 10920 O O   . HOH J 5 .   ? -2.999  -56.686 -10.998 1.00 36.75  ? 605 HOH B O   1 
HETATM 10921 O O   . HOH J 5 .   ? -15.639 -42.942 -11.481 1.00 44.96  ? 606 HOH B O   1 
HETATM 10922 O O   . HOH J 5 .   ? -5.811  -35.422 -39.070 1.00 47.10  ? 607 HOH B O   1 
HETATM 10923 O O   . HOH J 5 .   ? -3.210  -13.655 1.136   1.00 46.22  ? 608 HOH B O   1 
HETATM 10924 O O   . HOH J 5 .   ? -38.194 -53.397 1.190   1.00 55.23  ? 609 HOH B O   1 
HETATM 10925 O O   . HOH J 5 .   ? 2.231   -25.505 1.309   1.00 40.69  ? 610 HOH B O   1 
HETATM 10926 O O   . HOH J 5 .   ? -11.078 -40.471 -23.794 1.00 39.18  ? 611 HOH B O   1 
HETATM 10927 O O   . HOH J 5 .   ? -5.590  -28.611 6.291   1.00 39.73  ? 612 HOH B O   1 
HETATM 10928 O O   . HOH J 5 .   ? -7.225  -53.475 -45.307 1.00 53.07  ? 613 HOH B O   1 
HETATM 10929 O O   . HOH J 5 .   ? 1.821   -18.134 -16.036 1.00 32.35  ? 614 HOH B O   1 
HETATM 10930 O O   . HOH J 5 .   ? -5.256  -43.777 -16.170 1.00 41.90  ? 615 HOH B O   1 
HETATM 10931 O O   . HOH J 5 .   ? -4.089  -26.867 2.725   1.00 39.18  ? 616 HOH B O   1 
HETATM 10932 O O   . HOH J 5 .   ? 1.456   -31.718 -19.631 1.00 38.69  ? 617 HOH B O   1 
HETATM 10933 O O   . HOH J 5 .   ? -14.319 -19.778 4.035   1.00 43.95  ? 618 HOH B O   1 
HETATM 10934 O O   . HOH J 5 .   ? 2.675   -48.441 4.719   1.00 39.39  ? 619 HOH B O   1 
HETATM 10935 O O   . HOH J 5 .   ? -6.082  -26.792 4.674   1.00 33.89  ? 620 HOH B O   1 
HETATM 10936 O O   . HOH J 5 .   ? 10.448  -52.588 -4.703  1.00 55.42  ? 621 HOH B O   1 
HETATM 10937 O O   . HOH J 5 .   ? -9.674  -53.161 -15.106 1.00 41.92  ? 622 HOH B O   1 
HETATM 10938 O O   . HOH J 5 .   ? -2.545  -40.784 -30.522 1.00 48.20  ? 623 HOH B O   1 
HETATM 10939 O O   . HOH J 5 .   ? -20.662 -66.772 -3.764  1.00 59.73  ? 624 HOH B O   1 
HETATM 10940 O O   . HOH J 5 .   ? -25.923 -35.923 -0.660  1.00 58.98  ? 625 HOH B O   1 
HETATM 10941 O O   . HOH J 5 .   ? -13.272 -52.622 -35.817 1.00 42.85  ? 626 HOH B O   1 
HETATM 10942 O O   . HOH J 5 .   ? -20.762 -33.769 -0.923  1.00 44.85  ? 627 HOH B O   1 
HETATM 10943 O O   . HOH J 5 .   ? 0.585   -42.621 -22.127 1.00 51.60  ? 628 HOH B O   1 
HETATM 10944 O O   . HOH J 5 .   ? 4.779   -27.753 -4.592  1.00 39.54  ? 629 HOH B O   1 
HETATM 10945 O O   . HOH J 5 .   ? -37.750 -54.737 -3.346  1.00 66.25  ? 630 HOH B O   1 
HETATM 10946 O O   . HOH J 5 .   ? -17.362 -52.317 -0.871  1.00 59.74  ? 631 HOH B O   1 
HETATM 10947 O O   . HOH J 5 .   ? -2.295  -39.299 -19.066 1.00 51.16  ? 632 HOH B O   1 
HETATM 10948 O O   . HOH J 5 .   ? -14.051 -51.417 -31.468 1.00 47.79  ? 633 HOH B O   1 
HETATM 10949 O O   . HOH J 5 .   ? -8.885  -14.066 -2.222  1.00 41.40  ? 634 HOH B O   1 
HETATM 10950 O O   . HOH J 5 .   ? -23.908 -64.404 -18.062 1.00 60.61  ? 635 HOH B O   1 
HETATM 10951 O O   . HOH J 5 .   ? -25.325 -44.946 5.604   1.00 55.81  ? 636 HOH B O   1 
HETATM 10952 O O   . HOH J 5 .   ? 8.013   -30.202 -32.262 1.00 60.10  ? 637 HOH B O   1 
HETATM 10953 O O   . HOH J 5 .   ? -16.927 -54.871 -13.469 1.00 46.62  ? 638 HOH B O   1 
HETATM 10954 O O   . HOH J 5 .   ? -6.947  -22.259 10.511  1.00 42.26  ? 639 HOH B O   1 
HETATM 10955 O O   . HOH J 5 .   ? 1.582   -52.931 -17.464 1.00 46.43  ? 640 HOH B O   1 
HETATM 10956 O O   . HOH J 5 .   ? -4.056  -54.683 -23.725 1.00 46.19  ? 641 HOH B O   1 
HETATM 10957 O O   . HOH J 5 .   ? -2.332  -53.419 -25.473 1.00 57.29  ? 642 HOH B O   1 
HETATM 10958 O O   . HOH J 5 .   ? -12.645 -63.589 -10.066 1.00 53.58  ? 643 HOH B O   1 
HETATM 10959 O O   . HOH J 5 .   ? 6.095   -26.052 -5.720  1.00 43.71  ? 644 HOH B O   1 
HETATM 10960 O O   . HOH J 5 .   ? -0.638  -14.444 2.152   1.00 49.87  ? 645 HOH B O   1 
HETATM 10961 O O   . HOH J 5 .   ? -10.893 -55.436 -37.312 1.00 56.56  ? 646 HOH B O   1 
HETATM 10962 O O   . HOH J 5 .   ? -1.367  -27.580 12.314  1.00 62.94  ? 647 HOH B O   1 
HETATM 10963 O O   . HOH J 5 .   ? 14.348  -50.107 -24.494 1.00 55.53  ? 648 HOH B O   1 
HETATM 10964 O O   . HOH J 5 .   ? -6.859  -11.961 -3.189  1.00 55.41  ? 649 HOH B O   1 
HETATM 10965 O O   . HOH K 5 .   ? 27.119  -2.339  -4.432  1.00 38.84  ? 601 HOH C O   1 
HETATM 10966 O O   . HOH K 5 .   ? -5.415  -4.397  5.809   1.00 31.92  ? 602 HOH C O   1 
HETATM 10967 O O   . HOH K 5 .   ? 14.456  5.137   23.314  1.00 44.18  ? 603 HOH C O   1 
HETATM 10968 O O   . HOH K 5 .   ? 23.887  -9.459  11.203  1.00 35.09  ? 604 HOH C O   1 
HETATM 10969 O O   . HOH K 5 .   ? 15.793  -20.528 4.345   1.00 40.58  ? 605 HOH C O   1 
HETATM 10970 O O   . HOH K 5 .   ? -0.381  7.202   10.547  1.00 35.11  ? 606 HOH C O   1 
HETATM 10971 O O   . HOH K 5 .   ? 30.661  -13.301 11.297  1.00 50.31  ? 607 HOH C O   1 
HETATM 10972 O O   . HOH K 5 .   ? 24.719  -8.791  -19.849 1.00 42.25  ? 608 HOH C O   1 
HETATM 10973 O O   . HOH K 5 .   ? 17.525  16.441  9.901   1.00 38.87  ? 609 HOH C O   1 
HETATM 10974 O O   . HOH K 5 .   ? 22.367  14.829  -1.714  1.00 43.04  ? 610 HOH C O   1 
HETATM 10975 O O   . HOH K 5 .   ? 22.571  21.959  20.093  1.00 46.09  ? 611 HOH C O   1 
HETATM 10976 O O   . HOH K 5 .   ? 28.872  2.558   2.491   1.00 36.65  ? 612 HOH C O   1 
HETATM 10977 O O   . HOH K 5 .   ? 25.252  7.650   3.952   1.00 40.41  ? 613 HOH C O   1 
HETATM 10978 O O   . HOH K 5 .   ? 23.907  27.111  12.699  1.00 49.45  ? 614 HOH C O   1 
HETATM 10979 O O   . HOH K 5 .   ? 28.115  12.418  17.711  1.00 39.64  ? 615 HOH C O   1 
HETATM 10980 O O   . HOH K 5 .   ? 14.531  20.392  12.756  1.00 40.67  ? 616 HOH C O   1 
HETATM 10981 O O   . HOH K 5 .   ? 9.424   -4.251  13.924  1.00 39.58  ? 617 HOH C O   1 
HETATM 10982 O O   . HOH K 5 .   ? 39.201  -2.178  3.031   1.00 44.36  ? 618 HOH C O   1 
HETATM 10983 O O   . HOH K 5 .   ? 36.963  4.848   -5.954  1.00 42.97  ? 619 HOH C O   1 
HETATM 10984 O O   . HOH K 5 .   ? 15.043  17.609  17.810  1.00 39.92  ? 620 HOH C O   1 
HETATM 10985 O O   . HOH K 5 .   ? 24.184  13.582  9.525   1.00 51.83  ? 621 HOH C O   1 
HETATM 10986 O O   . HOH K 5 .   ? 16.686  15.218  21.305  1.00 46.08  ? 622 HOH C O   1 
HETATM 10987 O O   . HOH K 5 .   ? 13.110  10.848  10.658  1.00 45.76  ? 623 HOH C O   1 
HETATM 10988 O O   . HOH K 5 .   ? 14.323  32.913  -14.349 1.00 45.80  ? 624 HOH C O   1 
HETATM 10989 O O   . HOH K 5 .   ? 9.109   -6.879  -11.874 1.00 51.94  ? 625 HOH C O   1 
HETATM 10990 O O   . HOH K 5 .   ? 18.794  16.396  22.888  1.00 52.23  ? 626 HOH C O   1 
HETATM 10991 O O   . HOH K 5 .   ? -0.696  2.281   7.079   1.00 37.34  ? 627 HOH C O   1 
HETATM 10992 O O   . HOH K 5 .   ? 11.001  8.365   14.081  1.00 34.93  ? 628 HOH C O   1 
HETATM 10993 O O   . HOH K 5 .   ? 11.131  -4.594  -11.590 1.00 42.76  ? 629 HOH C O   1 
HETATM 10994 O O   . HOH K 5 .   ? 38.275  2.472   5.274   1.00 35.26  ? 630 HOH C O   1 
HETATM 10995 O O   . HOH K 5 .   ? 5.995   11.957  11.072  1.00 35.42  ? 631 HOH C O   1 
HETATM 10996 O O   . HOH K 5 .   ? 4.279   -19.472 2.530   1.00 40.49  ? 632 HOH C O   1 
HETATM 10997 O O   . HOH K 5 .   ? 30.715  13.837  7.385   1.00 46.91  ? 633 HOH C O   1 
HETATM 10998 O O   . HOH K 5 .   ? 1.720   -13.302 -5.265  1.00 37.37  ? 634 HOH C O   1 
HETATM 10999 O O   . HOH K 5 .   ? 32.851  10.457  11.823  1.00 41.21  ? 635 HOH C O   1 
HETATM 11000 O O   . HOH K 5 .   ? 7.678   -16.047 -7.773  1.00 52.78  ? 636 HOH C O   1 
HETATM 11001 O O   . HOH K 5 .   ? 34.570  9.151   10.290  1.00 36.41  ? 637 HOH C O   1 
HETATM 11002 O O   . HOH K 5 .   ? 28.993  32.846  14.872  1.00 57.13  ? 638 HOH C O   1 
HETATM 11003 O O   . HOH K 5 .   ? 22.483  21.784  6.780   1.00 52.20  ? 639 HOH C O   1 
HETATM 11004 O O   . HOH K 5 .   ? 26.660  -18.028 10.963  1.00 50.03  ? 640 HOH C O   1 
HETATM 11005 O O   . HOH K 5 .   ? 38.742  -7.683  -7.533  1.00 46.03  ? 641 HOH C O   1 
HETATM 11006 O O   . HOH K 5 .   ? 3.765   -14.207 -6.739  1.00 36.30  ? 642 HOH C O   1 
HETATM 11007 O O   . HOH K 5 .   ? 24.434  -0.275  -6.913  1.00 36.32  ? 643 HOH C O   1 
HETATM 11008 O O   . HOH K 5 .   ? 39.305  -5.384  5.200   1.00 45.68  ? 644 HOH C O   1 
HETATM 11009 O O   . HOH K 5 .   ? -2.668  -0.416  16.907  1.00 50.77  ? 645 HOH C O   1 
HETATM 11010 O O   . HOH K 5 .   ? 1.155   18.920  19.590  1.00 59.85  ? 646 HOH C O   1 
HETATM 11011 O O   . HOH K 5 .   ? 33.383  -3.156  -13.953 1.00 49.25  ? 647 HOH C O   1 
HETATM 11012 O O   . HOH K 5 .   ? 9.091   -20.732 8.140   1.00 47.26  ? 648 HOH C O   1 
HETATM 11013 O O   . HOH K 5 .   ? 26.267  -15.111 -16.141 1.00 46.82  ? 649 HOH C O   1 
HETATM 11014 O O   . HOH K 5 .   ? 29.795  8.759   -6.585  1.00 53.42  ? 650 HOH C O   1 
HETATM 11015 O O   . HOH K 5 .   ? 6.707   -10.033 11.788  1.00 38.99  ? 651 HOH C O   1 
HETATM 11016 O O   . HOH K 5 .   ? 28.010  -9.975  -25.212 1.00 51.45  ? 652 HOH C O   1 
HETATM 11017 O O   . HOH K 5 .   ? 8.794   -13.635 7.218   1.00 41.39  ? 653 HOH C O   1 
HETATM 11018 O O   . HOH K 5 .   ? 19.529  20.403  9.287   1.00 48.69  ? 654 HOH C O   1 
HETATM 11019 O O   . HOH K 5 .   ? 34.275  -4.812  -12.004 1.00 42.89  ? 655 HOH C O   1 
HETATM 11020 O O   . HOH K 5 .   ? 26.322  -15.912 16.652  1.00 46.60  ? 656 HOH C O   1 
HETATM 11021 O O   . HOH K 5 .   ? 42.615  39.102  -4.511  1.00 63.05  ? 657 HOH C O   1 
HETATM 11022 O O   . HOH K 5 .   ? 15.530  -8.469  -11.688 1.00 38.40  ? 658 HOH C O   1 
HETATM 11023 O O   . HOH K 5 .   ? 16.159  35.378  1.067   1.00 63.18  ? 659 HOH C O   1 
HETATM 11024 O O   . HOH K 5 .   ? 18.463  13.981  26.556  1.00 46.19  ? 660 HOH C O   1 
HETATM 11025 O O   . HOH K 5 .   ? 13.765  24.569  12.654  1.00 40.79  ? 661 HOH C O   1 
HETATM 11026 O O   . HOH K 5 .   ? 30.333  -1.022  -23.163 1.00 48.21  ? 662 HOH C O   1 
HETATM 11027 O O   . HOH K 5 .   ? 22.662  -20.925 0.524   1.00 41.13  ? 663 HOH C O   1 
HETATM 11028 O O   . HOH K 5 .   ? 36.100  -10.245 16.257  1.00 49.01  ? 664 HOH C O   1 
HETATM 11029 O O   . HOH K 5 .   ? 30.852  -17.522 -12.799 1.00 63.88  ? 665 HOH C O   1 
HETATM 11030 O O   . HOH K 5 .   ? 22.405  -9.526  -18.909 1.00 62.19  ? 666 HOH C O   1 
HETATM 11031 O O   . HOH K 5 .   ? -0.625  -12.346 -5.850  1.00 43.98  ? 667 HOH C O   1 
HETATM 11032 O O   . HOH K 5 .   ? 44.066  -3.213  10.539  1.00 63.52  ? 668 HOH C O   1 
HETATM 11033 O O   . HOH K 5 .   ? 23.838  -14.964 -17.671 1.00 56.03  ? 669 HOH C O   1 
HETATM 11034 O O   . HOH K 5 .   ? 25.411  -10.097 -24.388 1.00 54.65  ? 670 HOH C O   1 
HETATM 11035 O O   . HOH K 5 .   ? 41.600  -0.981  2.296   1.00 49.11  ? 671 HOH C O   1 
# 
