data_8XWM
# 
_entry.id   8XWM 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XWM         pdb_00008xwm 10.2210/pdb8xwm/pdb 
WWPDB D_1300044362 ?            ?                   
EMDB  EMD-38738    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-15 ? 
2 'Structure model' 1 1 2025-04-09 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.journal_volume'          
7  2 'Structure model' '_citation.page_first'              
8  2 'Structure model' '_citation.page_last'               
9  2 'Structure model' '_citation.pdbx_database_id_DOI'    
10 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 2 'Structure model' '_citation.title'                   
12 2 'Structure model' '_citation.year'                    
13 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XWM 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of CXCR2 bound to CXCL6 (Ligand-receptor focused map)' 
_pdbx_database_related.db_id          EMD-38738 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 arshukla@iitk.ac.in       Arun  Shukla K 'principal investigator/group leader' 0000-0003-2910-8288 
3 nureki@bs.s.u-tokyo.ac.jp Osamu Nureki ? 'principal investigator/group leader' 0000-0003-1813-7008 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Sano, F.K.'   1 0000-0002-8965-788X 
'Saha, S.'     2 0000-0002-0036-4969 
'Sharma, S.'   3 0009-0005-9109-9054 
'Ganguly, M.'  4 0009-0007-6165-3063 
'Shihoya, W.'  5 0000-0003-4813-5740 
'Nureki, O.'   6 0000-0003-1813-7008 
'Shukla, A.K.' 7 0000-0003-2910-8288 
'Banerjee, R.' 8 0000-0002-7751-2317 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mol.Cell 
_citation.journal_id_ASTM           MOCEFL 
_citation.journal_id_CSD            2168 
_citation.journal_id_ISSN           1097-2765 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            85 
_citation.language                  ? 
_citation.page_first                976 
_citation.page_last                 988.e9 
_citation.title                     
'Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.molcel.2025.01.024 
_citation.pdbx_database_id_PubMed   39978339 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Saha, S.'        1  ? 
primary 'Sano, F.K.'      2  ? 
primary 'Sharma, S.'      3  ? 
primary 'Ganguly, M.'     4  ? 
primary 'Mishra, S.'      5  ? 
primary 'Dalal, A.'       6  ? 
primary 'Akasaka, H.'     7  ? 
primary 'Kobayashi, T.A.' 8  ? 
primary 'Zaidi, N.'       9  ? 
primary 'Tiwari, D.'      10 ? 
primary 'Roy, N.'         11 ? 
primary 'Yadav, M.K.'     12 ? 
primary 'Banerjee, N.'    13 ? 
primary 'Saha, S.'        14 ? 
primary 'Mohapatra, S.'   15 ? 
primary 'Itoh, Y.'        16 ? 
primary 'Chevigne, A.'    17 ? 
primary 'Banerjee, R.'    18 ? 
primary 'Shihoya, W.'     19 ? 
primary 'Nureki, O.'      20 ? 
primary 'Shukla, A.K.'    21 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'C-X-C motif chemokine 6'         8328.941  1 ? ? ? ? 
2 polymer man 'C-X-C chemokine receptor type 2' 46699.609 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Chemokine alpha 3,CKA-3' 
2 CXC-R2,CXCR-2             
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no GPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN 
GPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN D ? 
2 'polypeptide(L)' no no 
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   PRO n 
1 3   VAL n 
1 4   SER n 
1 5   ALA n 
1 6   VAL n 
1 7   LEU n 
1 8   THR n 
1 9   GLU n 
1 10  LEU n 
1 11  ARG n 
1 12  CYS n 
1 13  THR n 
1 14  CYS n 
1 15  LEU n 
1 16  ARG n 
1 17  VAL n 
1 18  THR n 
1 19  LEU n 
1 20  ARG n 
1 21  VAL n 
1 22  ASN n 
1 23  PRO n 
1 24  LYS n 
1 25  THR n 
1 26  ILE n 
1 27  GLY n 
1 28  LYS n 
1 29  LEU n 
1 30  GLN n 
1 31  VAL n 
1 32  PHE n 
1 33  PRO n 
1 34  ALA n 
1 35  GLY n 
1 36  PRO n 
1 37  GLN n 
1 38  CYS n 
1 39  SER n 
1 40  LYS n 
1 41  VAL n 
1 42  GLU n 
1 43  VAL n 
1 44  VAL n 
1 45  ALA n 
1 46  SER n 
1 47  LEU n 
1 48  LYS n 
1 49  ASN n 
1 50  GLY n 
1 51  LYS n 
1 52  GLN n 
1 53  VAL n 
1 54  CYS n 
1 55  LEU n 
1 56  ASP n 
1 57  PRO n 
1 58  GLU n 
1 59  ALA n 
1 60  PRO n 
1 61  PHE n 
1 62  LEU n 
1 63  LYS n 
1 64  LYS n 
1 65  VAL n 
1 66  ILE n 
1 67  GLN n 
1 68  LYS n 
1 69  ILE n 
1 70  LEU n 
1 71  ASP n 
1 72  SER n 
1 73  GLY n 
1 74  ASN n 
1 75  LYS n 
1 76  LYS n 
1 77  ASN n 
2 1   MET n 
2 2   GLY n 
2 3   LYS n 
2 4   THR n 
2 5   ILE n 
2 6   ILE n 
2 7   ALA n 
2 8   LEU n 
2 9   SER n 
2 10  TYR n 
2 11  ILE n 
2 12  PHE n 
2 13  CYS n 
2 14  LEU n 
2 15  VAL n 
2 16  PHE n 
2 17  ALA n 
2 18  ASP n 
2 19  TYR n 
2 20  LYS n 
2 21  ASP n 
2 22  ASP n 
2 23  ASP n 
2 24  ASP n 
2 25  ALA n 
2 26  ALA n 
2 27  ASN n 
2 28  PHE n 
2 29  THR n 
2 30  PRO n 
2 31  VAL n 
2 32  ASN n 
2 33  GLY n 
2 34  SER n 
2 35  SER n 
2 36  GLY n 
2 37  ASN n 
2 38  GLN n 
2 39  SER n 
2 40  VAL n 
2 41  ARG n 
2 42  LEU n 
2 43  VAL n 
2 44  THR n 
2 45  SER n 
2 46  SER n 
2 47  SER n 
2 48  LEU n 
2 49  GLU n 
2 50  VAL n 
2 51  LEU n 
2 52  PHE n 
2 53  GLN n 
2 54  GLY n 
2 55  PRO n 
2 56  GLY n 
2 57  SER n 
2 58  GLU n 
2 59  ASP n 
2 60  PHE n 
2 61  ASN n 
2 62  MET n 
2 63  GLU n 
2 64  SER n 
2 65  ASP n 
2 66  SER n 
2 67  PHE n 
2 68  GLU n 
2 69  ASP n 
2 70  PHE n 
2 71  TRP n 
2 72  LYS n 
2 73  GLY n 
2 74  GLU n 
2 75  ASP n 
2 76  LEU n 
2 77  SER n 
2 78  ASN n 
2 79  TYR n 
2 80  SER n 
2 81  TYR n 
2 82  SER n 
2 83  SER n 
2 84  THR n 
2 85  LEU n 
2 86  PRO n 
2 87  PRO n 
2 88  PHE n 
2 89  LEU n 
2 90  LEU n 
2 91  ASP n 
2 92  ALA n 
2 93  ALA n 
2 94  PRO n 
2 95  CYS n 
2 96  GLU n 
2 97  PRO n 
2 98  GLU n 
2 99  SER n 
2 100 LEU n 
2 101 GLU n 
2 102 ILE n 
2 103 ASN n 
2 104 LYS n 
2 105 TYR n 
2 106 PHE n 
2 107 VAL n 
2 108 VAL n 
2 109 ILE n 
2 110 ILE n 
2 111 TYR n 
2 112 ALA n 
2 113 LEU n 
2 114 VAL n 
2 115 PHE n 
2 116 LEU n 
2 117 LEU n 
2 118 SER n 
2 119 LEU n 
2 120 LEU n 
2 121 GLY n 
2 122 ASN n 
2 123 SER n 
2 124 LEU n 
2 125 VAL n 
2 126 MET n 
2 127 LEU n 
2 128 VAL n 
2 129 ILE n 
2 130 LEU n 
2 131 TYR n 
2 132 SER n 
2 133 ARG n 
2 134 VAL n 
2 135 GLY n 
2 136 ARG n 
2 137 SER n 
2 138 VAL n 
2 139 THR n 
2 140 ASP n 
2 141 VAL n 
2 142 TYR n 
2 143 LEU n 
2 144 LEU n 
2 145 ASN n 
2 146 LEU n 
2 147 ALA n 
2 148 LEU n 
2 149 ALA n 
2 150 ASP n 
2 151 LEU n 
2 152 LEU n 
2 153 PHE n 
2 154 ALA n 
2 155 LEU n 
2 156 THR n 
2 157 LEU n 
2 158 PRO n 
2 159 ILE n 
2 160 TRP n 
2 161 ALA n 
2 162 ALA n 
2 163 SER n 
2 164 LYS n 
2 165 VAL n 
2 166 ASN n 
2 167 GLY n 
2 168 TRP n 
2 169 ILE n 
2 170 PHE n 
2 171 GLY n 
2 172 THR n 
2 173 PHE n 
2 174 LEU n 
2 175 CYS n 
2 176 LYS n 
2 177 VAL n 
2 178 VAL n 
2 179 SER n 
2 180 LEU n 
2 181 LEU n 
2 182 LYS n 
2 183 GLU n 
2 184 VAL n 
2 185 ASN n 
2 186 PHE n 
2 187 TYR n 
2 188 SER n 
2 189 GLY n 
2 190 ILE n 
2 191 LEU n 
2 192 LEU n 
2 193 LEU n 
2 194 ALA n 
2 195 CYS n 
2 196 ILE n 
2 197 SER n 
2 198 VAL n 
2 199 ASP n 
2 200 ARG n 
2 201 TYR n 
2 202 LEU n 
2 203 ALA n 
2 204 ILE n 
2 205 VAL n 
2 206 HIS n 
2 207 ALA n 
2 208 THR n 
2 209 ARG n 
2 210 THR n 
2 211 LEU n 
2 212 THR n 
2 213 GLN n 
2 214 LYS n 
2 215 ARG n 
2 216 TYR n 
2 217 LEU n 
2 218 VAL n 
2 219 LYS n 
2 220 PHE n 
2 221 ILE n 
2 222 CYS n 
2 223 LEU n 
2 224 SER n 
2 225 ILE n 
2 226 TRP n 
2 227 GLY n 
2 228 LEU n 
2 229 SER n 
2 230 LEU n 
2 231 LEU n 
2 232 LEU n 
2 233 ALA n 
2 234 LEU n 
2 235 PRO n 
2 236 VAL n 
2 237 LEU n 
2 238 LEU n 
2 239 PHE n 
2 240 ARG n 
2 241 ARG n 
2 242 THR n 
2 243 VAL n 
2 244 TYR n 
2 245 SER n 
2 246 SER n 
2 247 ASN n 
2 248 VAL n 
2 249 SER n 
2 250 PRO n 
2 251 ALA n 
2 252 CYS n 
2 253 TYR n 
2 254 GLU n 
2 255 ASP n 
2 256 MET n 
2 257 GLY n 
2 258 ASN n 
2 259 ASN n 
2 260 THR n 
2 261 ALA n 
2 262 ASN n 
2 263 TRP n 
2 264 ARG n 
2 265 MET n 
2 266 LEU n 
2 267 LEU n 
2 268 ARG n 
2 269 ILE n 
2 270 LEU n 
2 271 PRO n 
2 272 GLN n 
2 273 SER n 
2 274 PHE n 
2 275 GLY n 
2 276 PHE n 
2 277 ILE n 
2 278 VAL n 
2 279 PRO n 
2 280 LEU n 
2 281 LEU n 
2 282 ILE n 
2 283 MET n 
2 284 LEU n 
2 285 PHE n 
2 286 CYS n 
2 287 TYR n 
2 288 GLY n 
2 289 PHE n 
2 290 THR n 
2 291 LEU n 
2 292 ARG n 
2 293 THR n 
2 294 LEU n 
2 295 PHE n 
2 296 LYS n 
2 297 ALA n 
2 298 HIS n 
2 299 MET n 
2 300 GLY n 
2 301 GLN n 
2 302 LYS n 
2 303 HIS n 
2 304 ARG n 
2 305 ALA n 
2 306 MET n 
2 307 ARG n 
2 308 VAL n 
2 309 ILE n 
2 310 PHE n 
2 311 ALA n 
2 312 VAL n 
2 313 VAL n 
2 314 LEU n 
2 315 ILE n 
2 316 PHE n 
2 317 LEU n 
2 318 LEU n 
2 319 CYS n 
2 320 TRP n 
2 321 LEU n 
2 322 PRO n 
2 323 TYR n 
2 324 ASN n 
2 325 LEU n 
2 326 VAL n 
2 327 LEU n 
2 328 LEU n 
2 329 ALA n 
2 330 ASP n 
2 331 THR n 
2 332 LEU n 
2 333 MET n 
2 334 ARG n 
2 335 THR n 
2 336 GLN n 
2 337 VAL n 
2 338 ILE n 
2 339 GLN n 
2 340 GLU n 
2 341 THR n 
2 342 CYS n 
2 343 GLU n 
2 344 ARG n 
2 345 ARG n 
2 346 ASN n 
2 347 HIS n 
2 348 ILE n 
2 349 ASP n 
2 350 ARG n 
2 351 ALA n 
2 352 LEU n 
2 353 ASP n 
2 354 ALA n 
2 355 THR n 
2 356 GLU n 
2 357 ILE n 
2 358 LEU n 
2 359 GLY n 
2 360 ILE n 
2 361 LEU n 
2 362 HIS n 
2 363 SER n 
2 364 CYS n 
2 365 LEU n 
2 366 ASN n 
2 367 PRO n 
2 368 LEU n 
2 369 ILE n 
2 370 TYR n 
2 371 ALA n 
2 372 PHE n 
2 373 ILE n 
2 374 GLY n 
2 375 GLN n 
2 376 LYS n 
2 377 PHE n 
2 378 ARG n 
2 379 HIS n 
2 380 GLY n 
2 381 LEU n 
2 382 LEU n 
2 383 LYS n 
2 384 ILE n 
2 385 LEU n 
2 386 ALA n 
2 387 ILE n 
2 388 HIS n 
2 389 GLY n 
2 390 LEU n 
2 391 ILE n 
2 392 SER n 
2 393 LYS n 
2 394 ASP n 
2 395 SER n 
2 396 LEU n 
2 397 PRO n 
2 398 LYS n 
2 399 ASP n 
2 400 SER n 
2 401 ARG n 
2 402 PRO n 
2 403 SER n 
2 404 PHE n 
2 405 VAL n 
2 406 GLY n 
2 407 SER n 
2 408 SER n 
2 409 SER n 
2 410 GLY n 
2 411 HIS n 
2 412 THR n 
2 413 SER n 
2 414 THR n 
2 415 THR n 
2 416 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 77  human ? CXCL6 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli'      562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 416 human ? CXCR2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   1   ?   ?   ?   D . n 
A 1 2   PRO 2   2   ?   ?   ?   D . n 
A 1 3   VAL 3   3   ?   ?   ?   D . n 
A 1 4   SER 4   4   ?   ?   ?   D . n 
A 1 5   ALA 5   5   5   ALA ALA D . n 
A 1 6   VAL 6   6   6   VAL VAL D . n 
A 1 7   LEU 7   7   7   LEU LEU D . n 
A 1 8   THR 8   8   8   THR THR D . n 
A 1 9   GLU 9   9   9   GLU GLU D . n 
A 1 10  LEU 10  10  10  LEU LEU D . n 
A 1 11  ARG 11  11  11  ARG ARG D . n 
A 1 12  CYS 12  12  12  CYS CYS D . n 
A 1 13  THR 13  13  13  THR THR D . n 
A 1 14  CYS 14  14  14  CYS CYS D . n 
A 1 15  LEU 15  15  15  LEU LEU D . n 
A 1 16  ARG 16  16  16  ARG ARG D . n 
A 1 17  VAL 17  17  17  VAL VAL D . n 
A 1 18  THR 18  18  18  THR THR D . n 
A 1 19  LEU 19  19  19  LEU LEU D . n 
A 1 20  ARG 20  20  20  ARG ARG D . n 
A 1 21  VAL 21  21  21  VAL VAL D . n 
A 1 22  ASN 22  22  22  ASN ASN D . n 
A 1 23  PRO 23  23  23  PRO PRO D . n 
A 1 24  LYS 24  24  24  LYS LYS D . n 
A 1 25  THR 25  25  25  THR THR D . n 
A 1 26  ILE 26  26  26  ILE ILE D . n 
A 1 27  GLY 27  27  27  GLY GLY D . n 
A 1 28  LYS 28  28  28  LYS LYS D . n 
A 1 29  LEU 29  29  29  LEU LEU D . n 
A 1 30  GLN 30  30  30  GLN GLN D . n 
A 1 31  VAL 31  31  31  VAL VAL D . n 
A 1 32  PHE 32  32  32  PHE PHE D . n 
A 1 33  PRO 33  33  33  PRO PRO D . n 
A 1 34  ALA 34  34  34  ALA ALA D . n 
A 1 35  GLY 35  35  35  GLY GLY D . n 
A 1 36  PRO 36  36  36  PRO PRO D . n 
A 1 37  GLN 37  37  37  GLN GLN D . n 
A 1 38  CYS 38  38  38  CYS CYS D . n 
A 1 39  SER 39  39  39  SER SER D . n 
A 1 40  LYS 40  40  40  LYS LYS D . n 
A 1 41  VAL 41  41  41  VAL VAL D . n 
A 1 42  GLU 42  42  42  GLU GLU D . n 
A 1 43  VAL 43  43  43  VAL VAL D . n 
A 1 44  VAL 44  44  44  VAL VAL D . n 
A 1 45  ALA 45  45  45  ALA ALA D . n 
A 1 46  SER 46  46  46  SER SER D . n 
A 1 47  LEU 47  47  47  LEU LEU D . n 
A 1 48  LYS 48  48  48  LYS LYS D . n 
A 1 49  ASN 49  49  49  ASN ASN D . n 
A 1 50  GLY 50  50  50  GLY GLY D . n 
A 1 51  LYS 51  51  51  LYS LYS D . n 
A 1 52  GLN 52  52  52  GLN GLN D . n 
A 1 53  VAL 53  53  53  VAL VAL D . n 
A 1 54  CYS 54  54  54  CYS CYS D . n 
A 1 55  LEU 55  55  55  LEU LEU D . n 
A 1 56  ASP 56  56  56  ASP ASP D . n 
A 1 57  PRO 57  57  57  PRO PRO D . n 
A 1 58  GLU 58  58  58  GLU GLU D . n 
A 1 59  ALA 59  59  59  ALA ALA D . n 
A 1 60  PRO 60  60  60  PRO PRO D . n 
A 1 61  PHE 61  61  61  PHE PHE D . n 
A 1 62  LEU 62  62  62  LEU LEU D . n 
A 1 63  LYS 63  63  63  LYS LYS D . n 
A 1 64  LYS 64  64  64  LYS LYS D . n 
A 1 65  VAL 65  65  65  VAL VAL D . n 
A 1 66  ILE 66  66  66  ILE ILE D . n 
A 1 67  GLN 67  67  67  GLN GLN D . n 
A 1 68  LYS 68  68  68  LYS LYS D . n 
A 1 69  ILE 69  69  69  ILE ILE D . n 
A 1 70  LEU 70  70  ?   ?   ?   D . n 
A 1 71  ASP 71  71  ?   ?   ?   D . n 
A 1 72  SER 72  72  ?   ?   ?   D . n 
A 1 73  GLY 73  73  ?   ?   ?   D . n 
A 1 74  ASN 74  74  ?   ?   ?   D . n 
A 1 75  LYS 75  75  ?   ?   ?   D . n 
A 1 76  LYS 76  76  ?   ?   ?   D . n 
A 1 77  ASN 77  77  ?   ?   ?   D . n 
B 2 1   MET 1   -55 ?   ?   ?   R . n 
B 2 2   GLY 2   -54 ?   ?   ?   R . n 
B 2 3   LYS 3   -53 ?   ?   ?   R . n 
B 2 4   THR 4   -52 ?   ?   ?   R . n 
B 2 5   ILE 5   -51 ?   ?   ?   R . n 
B 2 6   ILE 6   -50 ?   ?   ?   R . n 
B 2 7   ALA 7   -49 ?   ?   ?   R . n 
B 2 8   LEU 8   -48 ?   ?   ?   R . n 
B 2 9   SER 9   -47 ?   ?   ?   R . n 
B 2 10  TYR 10  -46 ?   ?   ?   R . n 
B 2 11  ILE 11  -45 ?   ?   ?   R . n 
B 2 12  PHE 12  -44 ?   ?   ?   R . n 
B 2 13  CYS 13  -43 ?   ?   ?   R . n 
B 2 14  LEU 14  -42 ?   ?   ?   R . n 
B 2 15  VAL 15  -41 ?   ?   ?   R . n 
B 2 16  PHE 16  -40 ?   ?   ?   R . n 
B 2 17  ALA 17  -39 ?   ?   ?   R . n 
B 2 18  ASP 18  -38 ?   ?   ?   R . n 
B 2 19  TYR 19  -37 ?   ?   ?   R . n 
B 2 20  LYS 20  -36 ?   ?   ?   R . n 
B 2 21  ASP 21  -35 ?   ?   ?   R . n 
B 2 22  ASP 22  -34 ?   ?   ?   R . n 
B 2 23  ASP 23  -33 ?   ?   ?   R . n 
B 2 24  ASP 24  -32 ?   ?   ?   R . n 
B 2 25  ALA 25  -31 ?   ?   ?   R . n 
B 2 26  ALA 26  -30 ?   ?   ?   R . n 
B 2 27  ASN 27  -29 ?   ?   ?   R . n 
B 2 28  PHE 28  -28 ?   ?   ?   R . n 
B 2 29  THR 29  -27 ?   ?   ?   R . n 
B 2 30  PRO 30  -26 ?   ?   ?   R . n 
B 2 31  VAL 31  -25 ?   ?   ?   R . n 
B 2 32  ASN 32  -24 ?   ?   ?   R . n 
B 2 33  GLY 33  -23 ?   ?   ?   R . n 
B 2 34  SER 34  -22 ?   ?   ?   R . n 
B 2 35  SER 35  -21 ?   ?   ?   R . n 
B 2 36  GLY 36  -20 ?   ?   ?   R . n 
B 2 37  ASN 37  -19 ?   ?   ?   R . n 
B 2 38  GLN 38  -18 ?   ?   ?   R . n 
B 2 39  SER 39  -17 ?   ?   ?   R . n 
B 2 40  VAL 40  -16 ?   ?   ?   R . n 
B 2 41  ARG 41  -15 ?   ?   ?   R . n 
B 2 42  LEU 42  -14 ?   ?   ?   R . n 
B 2 43  VAL 43  -13 ?   ?   ?   R . n 
B 2 44  THR 44  -12 ?   ?   ?   R . n 
B 2 45  SER 45  -11 ?   ?   ?   R . n 
B 2 46  SER 46  -10 ?   ?   ?   R . n 
B 2 47  SER 47  -9  ?   ?   ?   R . n 
B 2 48  LEU 48  -8  ?   ?   ?   R . n 
B 2 49  GLU 49  -7  ?   ?   ?   R . n 
B 2 50  VAL 50  -6  ?   ?   ?   R . n 
B 2 51  LEU 51  -5  ?   ?   ?   R . n 
B 2 52  PHE 52  -4  ?   ?   ?   R . n 
B 2 53  GLN 53  -3  ?   ?   ?   R . n 
B 2 54  GLY 54  -2  ?   ?   ?   R . n 
B 2 55  PRO 55  -1  ?   ?   ?   R . n 
B 2 56  GLY 56  0   ?   ?   ?   R . n 
B 2 57  SER 57  1   ?   ?   ?   R . n 
B 2 58  GLU 58  2   ?   ?   ?   R . n 
B 2 59  ASP 59  3   ?   ?   ?   R . n 
B 2 60  PHE 60  4   ?   ?   ?   R . n 
B 2 61  ASN 61  5   ?   ?   ?   R . n 
B 2 62  MET 62  6   ?   ?   ?   R . n 
B 2 63  GLU 63  7   ?   ?   ?   R . n 
B 2 64  SER 64  8   ?   ?   ?   R . n 
B 2 65  ASP 65  9   ?   ?   ?   R . n 
B 2 66  SER 66  10  ?   ?   ?   R . n 
B 2 67  PHE 67  11  ?   ?   ?   R . n 
B 2 68  GLU 68  12  ?   ?   ?   R . n 
B 2 69  ASP 69  13  ?   ?   ?   R . n 
B 2 70  PHE 70  14  ?   ?   ?   R . n 
B 2 71  TRP 71  15  ?   ?   ?   R . n 
B 2 72  LYS 72  16  ?   ?   ?   R . n 
B 2 73  GLY 73  17  ?   ?   ?   R . n 
B 2 74  GLU 74  18  ?   ?   ?   R . n 
B 2 75  ASP 75  19  ?   ?   ?   R . n 
B 2 76  LEU 76  20  ?   ?   ?   R . n 
B 2 77  SER 77  21  ?   ?   ?   R . n 
B 2 78  ASN 78  22  ?   ?   ?   R . n 
B 2 79  TYR 79  23  ?   ?   ?   R . n 
B 2 80  SER 80  24  ?   ?   ?   R . n 
B 2 81  TYR 81  25  ?   ?   ?   R . n 
B 2 82  SER 82  26  ?   ?   ?   R . n 
B 2 83  SER 83  27  ?   ?   ?   R . n 
B 2 84  THR 84  28  ?   ?   ?   R . n 
B 2 85  LEU 85  29  ?   ?   ?   R . n 
B 2 86  PRO 86  30  ?   ?   ?   R . n 
B 2 87  PRO 87  31  ?   ?   ?   R . n 
B 2 88  PHE 88  32  ?   ?   ?   R . n 
B 2 89  LEU 89  33  33  LEU LEU R . n 
B 2 90  LEU 90  34  34  LEU LEU R . n 
B 2 91  ASP 91  35  35  ASP ASP R . n 
B 2 92  ALA 92  36  36  ALA ALA R . n 
B 2 93  ALA 93  37  37  ALA ALA R . n 
B 2 94  PRO 94  38  38  PRO PRO R . n 
B 2 95  CYS 95  39  39  CYS CYS R . n 
B 2 96  GLU 96  40  40  GLU GLU R . n 
B 2 97  PRO 97  41  41  PRO PRO R . n 
B 2 98  GLU 98  42  42  GLU GLU R . n 
B 2 99  SER 99  43  43  SER SER R . n 
B 2 100 LEU 100 44  44  LEU LEU R . n 
B 2 101 GLU 101 45  45  GLU GLU R . n 
B 2 102 ILE 102 46  46  ILE ILE R . n 
B 2 103 ASN 103 47  47  ASN ASN R . n 
B 2 104 LYS 104 48  48  LYS LYS R . n 
B 2 105 TYR 105 49  49  TYR TYR R . n 
B 2 106 PHE 106 50  50  PHE PHE R . n 
B 2 107 VAL 107 51  51  VAL VAL R . n 
B 2 108 VAL 108 52  52  VAL VAL R . n 
B 2 109 ILE 109 53  53  ILE ILE R . n 
B 2 110 ILE 110 54  54  ILE ILE R . n 
B 2 111 TYR 111 55  55  TYR TYR R . n 
B 2 112 ALA 112 56  56  ALA ALA R . n 
B 2 113 LEU 113 57  57  LEU LEU R . n 
B 2 114 VAL 114 58  58  VAL VAL R . n 
B 2 115 PHE 115 59  59  PHE PHE R . n 
B 2 116 LEU 116 60  60  LEU LEU R . n 
B 2 117 LEU 117 61  61  LEU LEU R . n 
B 2 118 SER 118 62  62  SER SER R . n 
B 2 119 LEU 119 63  63  LEU LEU R . n 
B 2 120 LEU 120 64  64  LEU LEU R . n 
B 2 121 GLY 121 65  65  GLY GLY R . n 
B 2 122 ASN 122 66  66  ASN ASN R . n 
B 2 123 SER 123 67  67  SER SER R . n 
B 2 124 LEU 124 68  68  LEU LEU R . n 
B 2 125 VAL 125 69  69  VAL VAL R . n 
B 2 126 MET 126 70  70  MET MET R . n 
B 2 127 LEU 127 71  71  LEU LEU R . n 
B 2 128 VAL 128 72  72  VAL VAL R . n 
B 2 129 ILE 129 73  73  ILE ILE R . n 
B 2 130 LEU 130 74  74  LEU LEU R . n 
B 2 131 TYR 131 75  75  TYR TYR R . n 
B 2 132 SER 132 76  76  SER SER R . n 
B 2 133 ARG 133 77  77  ARG ARG R . n 
B 2 134 VAL 134 78  78  VAL VAL R . n 
B 2 135 GLY 135 79  79  GLY GLY R . n 
B 2 136 ARG 136 80  80  ARG ARG R . n 
B 2 137 SER 137 81  81  SER SER R . n 
B 2 138 VAL 138 82  82  VAL VAL R . n 
B 2 139 THR 139 83  83  THR THR R . n 
B 2 140 ASP 140 84  84  ASP ASP R . n 
B 2 141 VAL 141 85  85  VAL VAL R . n 
B 2 142 TYR 142 86  86  TYR TYR R . n 
B 2 143 LEU 143 87  87  LEU LEU R . n 
B 2 144 LEU 144 88  88  LEU LEU R . n 
B 2 145 ASN 145 89  89  ASN ASN R . n 
B 2 146 LEU 146 90  90  LEU LEU R . n 
B 2 147 ALA 147 91  91  ALA ALA R . n 
B 2 148 LEU 148 92  92  LEU LEU R . n 
B 2 149 ALA 149 93  93  ALA ALA R . n 
B 2 150 ASP 150 94  94  ASP ASP R . n 
B 2 151 LEU 151 95  95  LEU LEU R . n 
B 2 152 LEU 152 96  96  LEU LEU R . n 
B 2 153 PHE 153 97  97  PHE PHE R . n 
B 2 154 ALA 154 98  98  ALA ALA R . n 
B 2 155 LEU 155 99  99  LEU LEU R . n 
B 2 156 THR 156 100 100 THR THR R . n 
B 2 157 LEU 157 101 101 LEU LEU R . n 
B 2 158 PRO 158 102 102 PRO PRO R . n 
B 2 159 ILE 159 103 103 ILE ILE R . n 
B 2 160 TRP 160 104 104 TRP TRP R . n 
B 2 161 ALA 161 105 105 ALA ALA R . n 
B 2 162 ALA 162 106 106 ALA ALA R . n 
B 2 163 SER 163 107 107 SER SER R . n 
B 2 164 LYS 164 108 108 LYS LYS R . n 
B 2 165 VAL 165 109 109 VAL VAL R . n 
B 2 166 ASN 166 110 110 ASN ASN R . n 
B 2 167 GLY 167 111 111 GLY GLY R . n 
B 2 168 TRP 168 112 112 TRP TRP R . n 
B 2 169 ILE 169 113 113 ILE ILE R . n 
B 2 170 PHE 170 114 114 PHE PHE R . n 
B 2 171 GLY 171 115 115 GLY GLY R . n 
B 2 172 THR 172 116 116 THR THR R . n 
B 2 173 PHE 173 117 117 PHE PHE R . n 
B 2 174 LEU 174 118 118 LEU LEU R . n 
B 2 175 CYS 175 119 119 CYS CYS R . n 
B 2 176 LYS 176 120 120 LYS LYS R . n 
B 2 177 VAL 177 121 121 VAL VAL R . n 
B 2 178 VAL 178 122 122 VAL VAL R . n 
B 2 179 SER 179 123 123 SER SER R . n 
B 2 180 LEU 180 124 124 LEU LEU R . n 
B 2 181 LEU 181 125 125 LEU LEU R . n 
B 2 182 LYS 182 126 126 LYS LYS R . n 
B 2 183 GLU 183 127 127 GLU GLU R . n 
B 2 184 VAL 184 128 128 VAL VAL R . n 
B 2 185 ASN 185 129 129 ASN ASN R . n 
B 2 186 PHE 186 130 130 PHE PHE R . n 
B 2 187 TYR 187 131 131 TYR TYR R . n 
B 2 188 SER 188 132 132 SER SER R . n 
B 2 189 GLY 189 133 133 GLY GLY R . n 
B 2 190 ILE 190 134 134 ILE ILE R . n 
B 2 191 LEU 191 135 135 LEU LEU R . n 
B 2 192 LEU 192 136 136 LEU LEU R . n 
B 2 193 LEU 193 137 137 LEU LEU R . n 
B 2 194 ALA 194 138 138 ALA ALA R . n 
B 2 195 CYS 195 139 139 CYS CYS R . n 
B 2 196 ILE 196 140 140 ILE ILE R . n 
B 2 197 SER 197 141 141 SER SER R . n 
B 2 198 VAL 198 142 142 VAL VAL R . n 
B 2 199 ASP 199 143 143 ASP ASP R . n 
B 2 200 ARG 200 144 144 ARG ARG R . n 
B 2 201 TYR 201 145 145 TYR TYR R . n 
B 2 202 LEU 202 146 146 LEU LEU R . n 
B 2 203 ALA 203 147 147 ALA ALA R . n 
B 2 204 ILE 204 148 148 ILE ILE R . n 
B 2 205 VAL 205 149 149 VAL VAL R . n 
B 2 206 HIS 206 150 150 HIS HIS R . n 
B 2 207 ALA 207 151 151 ALA ALA R . n 
B 2 208 THR 208 152 152 THR THR R . n 
B 2 209 ARG 209 153 153 ARG ARG R . n 
B 2 210 THR 210 154 154 THR THR R . n 
B 2 211 LEU 211 155 155 LEU LEU R . n 
B 2 212 THR 212 156 156 THR THR R . n 
B 2 213 GLN 213 157 157 GLN GLN R . n 
B 2 214 LYS 214 158 158 LYS LYS R . n 
B 2 215 ARG 215 159 159 ARG ARG R . n 
B 2 216 TYR 216 160 160 TYR TYR R . n 
B 2 217 LEU 217 161 161 LEU LEU R . n 
B 2 218 VAL 218 162 162 VAL VAL R . n 
B 2 219 LYS 219 163 163 LYS LYS R . n 
B 2 220 PHE 220 164 164 PHE PHE R . n 
B 2 221 ILE 221 165 165 ILE ILE R . n 
B 2 222 CYS 222 166 166 CYS CYS R . n 
B 2 223 LEU 223 167 167 LEU LEU R . n 
B 2 224 SER 224 168 168 SER SER R . n 
B 2 225 ILE 225 169 169 ILE ILE R . n 
B 2 226 TRP 226 170 170 TRP TRP R . n 
B 2 227 GLY 227 171 171 GLY GLY R . n 
B 2 228 LEU 228 172 172 LEU LEU R . n 
B 2 229 SER 229 173 173 SER SER R . n 
B 2 230 LEU 230 174 174 LEU LEU R . n 
B 2 231 LEU 231 175 175 LEU LEU R . n 
B 2 232 LEU 232 176 176 LEU LEU R . n 
B 2 233 ALA 233 177 177 ALA ALA R . n 
B 2 234 LEU 234 178 178 LEU LEU R . n 
B 2 235 PRO 235 179 179 PRO PRO R . n 
B 2 236 VAL 236 180 180 VAL VAL R . n 
B 2 237 LEU 237 181 181 LEU LEU R . n 
B 2 238 LEU 238 182 182 LEU LEU R . n 
B 2 239 PHE 239 183 183 PHE PHE R . n 
B 2 240 ARG 240 184 184 ARG ARG R . n 
B 2 241 ARG 241 185 185 ARG ARG R . n 
B 2 242 THR 242 186 186 THR THR R . n 
B 2 243 VAL 243 187 187 VAL VAL R . n 
B 2 244 TYR 244 188 188 TYR TYR R . n 
B 2 245 SER 245 189 189 SER SER R . n 
B 2 246 SER 246 190 190 SER SER R . n 
B 2 247 ASN 247 191 191 ASN ASN R . n 
B 2 248 VAL 248 192 192 VAL VAL R . n 
B 2 249 SER 249 193 193 SER SER R . n 
B 2 250 PRO 250 194 194 PRO PRO R . n 
B 2 251 ALA 251 195 195 ALA ALA R . n 
B 2 252 CYS 252 196 196 CYS CYS R . n 
B 2 253 TYR 253 197 197 TYR TYR R . n 
B 2 254 GLU 254 198 198 GLU GLU R . n 
B 2 255 ASP 255 199 199 ASP ASP R . n 
B 2 256 MET 256 200 200 MET MET R . n 
B 2 257 GLY 257 201 201 GLY GLY R . n 
B 2 258 ASN 258 202 202 ASN ASN R . n 
B 2 259 ASN 259 203 203 ASN ASN R . n 
B 2 260 THR 260 204 204 THR THR R . n 
B 2 261 ALA 261 205 205 ALA ALA R . n 
B 2 262 ASN 262 206 206 ASN ASN R . n 
B 2 263 TRP 263 207 207 TRP TRP R . n 
B 2 264 ARG 264 208 208 ARG ARG R . n 
B 2 265 MET 265 209 209 MET MET R . n 
B 2 266 LEU 266 210 210 LEU LEU R . n 
B 2 267 LEU 267 211 211 LEU LEU R . n 
B 2 268 ARG 268 212 212 ARG ARG R . n 
B 2 269 ILE 269 213 213 ILE ILE R . n 
B 2 270 LEU 270 214 214 LEU LEU R . n 
B 2 271 PRO 271 215 215 PRO PRO R . n 
B 2 272 GLN 272 216 216 GLN GLN R . n 
B 2 273 SER 273 217 217 SER SER R . n 
B 2 274 PHE 274 218 218 PHE PHE R . n 
B 2 275 GLY 275 219 219 GLY GLY R . n 
B 2 276 PHE 276 220 220 PHE PHE R . n 
B 2 277 ILE 277 221 221 ILE ILE R . n 
B 2 278 VAL 278 222 222 VAL VAL R . n 
B 2 279 PRO 279 223 223 PRO PRO R . n 
B 2 280 LEU 280 224 224 LEU LEU R . n 
B 2 281 LEU 281 225 225 LEU LEU R . n 
B 2 282 ILE 282 226 226 ILE ILE R . n 
B 2 283 MET 283 227 227 MET MET R . n 
B 2 284 LEU 284 228 228 LEU LEU R . n 
B 2 285 PHE 285 229 229 PHE PHE R . n 
B 2 286 CYS 286 230 230 CYS CYS R . n 
B 2 287 TYR 287 231 231 TYR TYR R . n 
B 2 288 GLY 288 232 232 GLY GLY R . n 
B 2 289 PHE 289 233 233 PHE PHE R . n 
B 2 290 THR 290 234 234 THR THR R . n 
B 2 291 LEU 291 235 235 LEU LEU R . n 
B 2 292 ARG 292 236 236 ARG ARG R . n 
B 2 293 THR 293 237 237 THR THR R . n 
B 2 294 LEU 294 238 238 LEU LEU R . n 
B 2 295 PHE 295 239 239 PHE PHE R . n 
B 2 296 LYS 296 240 240 LYS LYS R . n 
B 2 297 ALA 297 241 241 ALA ALA R . n 
B 2 298 HIS 298 242 242 HIS HIS R . n 
B 2 299 MET 299 243 243 MET MET R . n 
B 2 300 GLY 300 244 244 GLY GLY R . n 
B 2 301 GLN 301 245 245 GLN GLN R . n 
B 2 302 LYS 302 246 246 LYS LYS R . n 
B 2 303 HIS 303 247 247 HIS HIS R . n 
B 2 304 ARG 304 248 248 ARG ARG R . n 
B 2 305 ALA 305 249 249 ALA ALA R . n 
B 2 306 MET 306 250 250 MET MET R . n 
B 2 307 ARG 307 251 251 ARG ARG R . n 
B 2 308 VAL 308 252 252 VAL VAL R . n 
B 2 309 ILE 309 253 253 ILE ILE R . n 
B 2 310 PHE 310 254 254 PHE PHE R . n 
B 2 311 ALA 311 255 255 ALA ALA R . n 
B 2 312 VAL 312 256 256 VAL VAL R . n 
B 2 313 VAL 313 257 257 VAL VAL R . n 
B 2 314 LEU 314 258 258 LEU LEU R . n 
B 2 315 ILE 315 259 259 ILE ILE R . n 
B 2 316 PHE 316 260 260 PHE PHE R . n 
B 2 317 LEU 317 261 261 LEU LEU R . n 
B 2 318 LEU 318 262 262 LEU LEU R . n 
B 2 319 CYS 319 263 263 CYS CYS R . n 
B 2 320 TRP 320 264 264 TRP TRP R . n 
B 2 321 LEU 321 265 265 LEU LEU R . n 
B 2 322 PRO 322 266 266 PRO PRO R . n 
B 2 323 TYR 323 267 267 TYR TYR R . n 
B 2 324 ASN 324 268 268 ASN ASN R . n 
B 2 325 LEU 325 269 269 LEU LEU R . n 
B 2 326 VAL 326 270 270 VAL VAL R . n 
B 2 327 LEU 327 271 271 LEU LEU R . n 
B 2 328 LEU 328 272 272 LEU LEU R . n 
B 2 329 ALA 329 273 273 ALA ALA R . n 
B 2 330 ASP 330 274 274 ASP ASP R . n 
B 2 331 THR 331 275 275 THR THR R . n 
B 2 332 LEU 332 276 276 LEU LEU R . n 
B 2 333 MET 333 277 277 MET MET R . n 
B 2 334 ARG 334 278 278 ARG ARG R . n 
B 2 335 THR 335 279 279 THR THR R . n 
B 2 336 GLN 336 280 280 GLN GLN R . n 
B 2 337 VAL 337 281 281 VAL VAL R . n 
B 2 338 ILE 338 282 282 ILE ILE R . n 
B 2 339 GLN 339 283 283 GLN GLN R . n 
B 2 340 GLU 340 284 284 GLU GLU R . n 
B 2 341 THR 341 285 285 THR THR R . n 
B 2 342 CYS 342 286 286 CYS CYS R . n 
B 2 343 GLU 343 287 287 GLU GLU R . n 
B 2 344 ARG 344 288 288 ARG ARG R . n 
B 2 345 ARG 345 289 289 ARG ARG R . n 
B 2 346 ASN 346 290 290 ASN ASN R . n 
B 2 347 HIS 347 291 291 HIS HIS R . n 
B 2 348 ILE 348 292 292 ILE ILE R . n 
B 2 349 ASP 349 293 293 ASP ASP R . n 
B 2 350 ARG 350 294 294 ARG ARG R . n 
B 2 351 ALA 351 295 295 ALA ALA R . n 
B 2 352 LEU 352 296 296 LEU LEU R . n 
B 2 353 ASP 353 297 297 ASP ASP R . n 
B 2 354 ALA 354 298 298 ALA ALA R . n 
B 2 355 THR 355 299 299 THR THR R . n 
B 2 356 GLU 356 300 300 GLU GLU R . n 
B 2 357 ILE 357 301 301 ILE ILE R . n 
B 2 358 LEU 358 302 302 LEU LEU R . n 
B 2 359 GLY 359 303 303 GLY GLY R . n 
B 2 360 ILE 360 304 304 ILE ILE R . n 
B 2 361 LEU 361 305 305 LEU LEU R . n 
B 2 362 HIS 362 306 306 HIS HIS R . n 
B 2 363 SER 363 307 307 SER SER R . n 
B 2 364 CYS 364 308 308 CYS CYS R . n 
B 2 365 LEU 365 309 309 LEU LEU R . n 
B 2 366 ASN 366 310 310 ASN ASN R . n 
B 2 367 PRO 367 311 311 PRO PRO R . n 
B 2 368 LEU 368 312 312 LEU LEU R . n 
B 2 369 ILE 369 313 313 ILE ILE R . n 
B 2 370 TYR 370 314 314 TYR TYR R . n 
B 2 371 ALA 371 315 315 ALA ALA R . n 
B 2 372 PHE 372 316 316 PHE PHE R . n 
B 2 373 ILE 373 317 317 ILE ILE R . n 
B 2 374 GLY 374 318 318 GLY GLY R . n 
B 2 375 GLN 375 319 319 GLN GLN R . n 
B 2 376 LYS 376 320 320 LYS LYS R . n 
B 2 377 PHE 377 321 321 PHE PHE R . n 
B 2 378 ARG 378 322 322 ARG ARG R . n 
B 2 379 HIS 379 323 323 HIS HIS R . n 
B 2 380 GLY 380 324 324 GLY GLY R . n 
B 2 381 LEU 381 325 325 LEU LEU R . n 
B 2 382 LEU 382 326 326 LEU LEU R . n 
B 2 383 LYS 383 327 327 LYS LYS R . n 
B 2 384 ILE 384 328 328 ILE ILE R . n 
B 2 385 LEU 385 329 329 LEU LEU R . n 
B 2 386 ALA 386 330 330 ALA ALA R . n 
B 2 387 ILE 387 331 ?   ?   ?   R . n 
B 2 388 HIS 388 332 ?   ?   ?   R . n 
B 2 389 GLY 389 333 ?   ?   ?   R . n 
B 2 390 LEU 390 334 ?   ?   ?   R . n 
B 2 391 ILE 391 335 ?   ?   ?   R . n 
B 2 392 SER 392 336 ?   ?   ?   R . n 
B 2 393 LYS 393 337 ?   ?   ?   R . n 
B 2 394 ASP 394 338 ?   ?   ?   R . n 
B 2 395 SER 395 339 ?   ?   ?   R . n 
B 2 396 LEU 396 340 ?   ?   ?   R . n 
B 2 397 PRO 397 341 ?   ?   ?   R . n 
B 2 398 LYS 398 342 ?   ?   ?   R . n 
B 2 399 ASP 399 343 ?   ?   ?   R . n 
B 2 400 SER 400 344 ?   ?   ?   R . n 
B 2 401 ARG 401 345 ?   ?   ?   R . n 
B 2 402 PRO 402 346 ?   ?   ?   R . n 
B 2 403 SER 403 347 ?   ?   ?   R . n 
B 2 404 PHE 404 348 ?   ?   ?   R . n 
B 2 405 VAL 405 349 ?   ?   ?   R . n 
B 2 406 GLY 406 350 ?   ?   ?   R . n 
B 2 407 SER 407 351 ?   ?   ?   R . n 
B 2 408 SER 408 352 ?   ?   ?   R . n 
B 2 409 SER 409 353 ?   ?   ?   R . n 
B 2 410 GLY 410 354 ?   ?   ?   R . n 
B 2 411 HIS 411 355 ?   ?   ?   R . n 
B 2 412 THR 412 356 ?   ?   ?   R . n 
B 2 413 SER 413 357 ?   ?   ?   R . n 
B 2 414 THR 414 358 ?   ?   ?   R . n 
B 2 415 THR 415 359 ?   ?   ?   R . n 
B 2 416 LEU 416 360 ?   ?   ?   R . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 D THR 18  ? OG1 ? A THR 18  OG1 
2   1 Y 1 D THR 18  ? CG2 ? A THR 18  CG2 
3   1 Y 1 D LEU 19  ? CG  ? A LEU 19  CG  
4   1 Y 1 D LEU 19  ? CD1 ? A LEU 19  CD1 
5   1 Y 1 D LEU 19  ? CD2 ? A LEU 19  CD2 
6   1 Y 1 D ARG 20  ? CG  ? A ARG 20  CG  
7   1 Y 1 D ARG 20  ? CD  ? A ARG 20  CD  
8   1 Y 1 D ARG 20  ? NE  ? A ARG 20  NE  
9   1 Y 1 D ARG 20  ? CZ  ? A ARG 20  CZ  
10  1 Y 1 D ARG 20  ? NH1 ? A ARG 20  NH1 
11  1 Y 1 D ARG 20  ? NH2 ? A ARG 20  NH2 
12  1 Y 1 D LYS 24  ? CG  ? A LYS 24  CG  
13  1 Y 1 D LYS 24  ? CD  ? A LYS 24  CD  
14  1 Y 1 D LYS 24  ? CE  ? A LYS 24  CE  
15  1 Y 1 D LYS 24  ? NZ  ? A LYS 24  NZ  
16  1 Y 1 D ILE 26  ? CG1 ? A ILE 26  CG1 
17  1 Y 1 D ILE 26  ? CG2 ? A ILE 26  CG2 
18  1 Y 1 D ILE 26  ? CD1 ? A ILE 26  CD1 
19  1 Y 1 D LYS 28  ? CG  ? A LYS 28  CG  
20  1 Y 1 D LYS 28  ? CD  ? A LYS 28  CD  
21  1 Y 1 D LYS 28  ? CE  ? A LYS 28  CE  
22  1 Y 1 D LYS 28  ? NZ  ? A LYS 28  NZ  
23  1 Y 1 D LEU 29  ? CG  ? A LEU 29  CG  
24  1 Y 1 D LEU 29  ? CD1 ? A LEU 29  CD1 
25  1 Y 1 D LEU 29  ? CD2 ? A LEU 29  CD2 
26  1 Y 1 D GLN 30  ? CG  ? A GLN 30  CG  
27  1 Y 1 D GLN 30  ? CD  ? A GLN 30  CD  
28  1 Y 1 D GLN 30  ? OE1 ? A GLN 30  OE1 
29  1 Y 1 D GLN 30  ? NE2 ? A GLN 30  NE2 
30  1 Y 1 D LYS 40  ? CG  ? A LYS 40  CG  
31  1 Y 1 D LYS 40  ? CD  ? A LYS 40  CD  
32  1 Y 1 D LYS 40  ? CE  ? A LYS 40  CE  
33  1 Y 1 D LYS 40  ? NZ  ? A LYS 40  NZ  
34  1 Y 1 D GLU 42  ? CG  ? A GLU 42  CG  
35  1 Y 1 D GLU 42  ? CD  ? A GLU 42  CD  
36  1 Y 1 D GLU 42  ? OE1 ? A GLU 42  OE1 
37  1 Y 1 D GLU 42  ? OE2 ? A GLU 42  OE2 
38  1 Y 1 D VAL 43  ? CG1 ? A VAL 43  CG1 
39  1 Y 1 D VAL 43  ? CG2 ? A VAL 43  CG2 
40  1 Y 1 D LEU 47  ? CG  ? A LEU 47  CG  
41  1 Y 1 D LEU 47  ? CD1 ? A LEU 47  CD1 
42  1 Y 1 D LEU 47  ? CD2 ? A LEU 47  CD2 
43  1 Y 1 D LYS 48  ? CG  ? A LYS 48  CG  
44  1 Y 1 D LYS 48  ? CD  ? A LYS 48  CD  
45  1 Y 1 D LYS 48  ? CE  ? A LYS 48  CE  
46  1 Y 1 D LYS 48  ? NZ  ? A LYS 48  NZ  
47  1 Y 1 D ASN 49  ? CG  ? A ASN 49  CG  
48  1 Y 1 D ASN 49  ? OD1 ? A ASN 49  OD1 
49  1 Y 1 D ASN 49  ? ND2 ? A ASN 49  ND2 
50  1 Y 1 D LYS 51  ? CG  ? A LYS 51  CG  
51  1 Y 1 D LYS 51  ? CD  ? A LYS 51  CD  
52  1 Y 1 D LYS 51  ? CE  ? A LYS 51  CE  
53  1 Y 1 D LYS 51  ? NZ  ? A LYS 51  NZ  
54  1 Y 1 D ASP 56  ? CG  ? A ASP 56  CG  
55  1 Y 1 D ASP 56  ? OD1 ? A ASP 56  OD1 
56  1 Y 1 D ASP 56  ? OD2 ? A ASP 56  OD2 
57  1 Y 1 D GLU 58  ? CG  ? A GLU 58  CG  
58  1 Y 1 D GLU 58  ? CD  ? A GLU 58  CD  
59  1 Y 1 D GLU 58  ? OE1 ? A GLU 58  OE1 
60  1 Y 1 D GLU 58  ? OE2 ? A GLU 58  OE2 
61  1 Y 1 D LEU 62  ? CG  ? A LEU 62  CG  
62  1 Y 1 D LEU 62  ? CD1 ? A LEU 62  CD1 
63  1 Y 1 D LEU 62  ? CD2 ? A LEU 62  CD2 
64  1 Y 1 D LYS 63  ? CG  ? A LYS 63  CG  
65  1 Y 1 D LYS 63  ? CD  ? A LYS 63  CD  
66  1 Y 1 D LYS 63  ? CE  ? A LYS 63  CE  
67  1 Y 1 D LYS 63  ? NZ  ? A LYS 63  NZ  
68  1 Y 1 D LYS 64  ? CG  ? A LYS 64  CG  
69  1 Y 1 D LYS 64  ? CD  ? A LYS 64  CD  
70  1 Y 1 D LYS 64  ? CE  ? A LYS 64  CE  
71  1 Y 1 D LYS 64  ? NZ  ? A LYS 64  NZ  
72  1 Y 1 D ILE 66  ? CG1 ? A ILE 66  CG1 
73  1 Y 1 D ILE 66  ? CG2 ? A ILE 66  CG2 
74  1 Y 1 D ILE 66  ? CD1 ? A ILE 66  CD1 
75  1 Y 1 D GLN 67  ? CG  ? A GLN 67  CG  
76  1 Y 1 D GLN 67  ? CD  ? A GLN 67  CD  
77  1 Y 1 D GLN 67  ? OE1 ? A GLN 67  OE1 
78  1 Y 1 D GLN 67  ? NE2 ? A GLN 67  NE2 
79  1 Y 1 D LYS 68  ? CG  ? A LYS 68  CG  
80  1 Y 1 D LYS 68  ? CD  ? A LYS 68  CD  
81  1 Y 1 D LYS 68  ? CE  ? A LYS 68  CE  
82  1 Y 1 D LYS 68  ? NZ  ? A LYS 68  NZ  
83  1 Y 1 R LEU 33  ? CG  ? B LEU 89  CG  
84  1 Y 1 R LEU 33  ? CD1 ? B LEU 89  CD1 
85  1 Y 1 R LEU 33  ? CD2 ? B LEU 89  CD2 
86  1 Y 1 R LEU 34  ? CG  ? B LEU 90  CG  
87  1 Y 1 R LEU 34  ? CD1 ? B LEU 90  CD1 
88  1 Y 1 R LEU 34  ? CD2 ? B LEU 90  CD2 
89  1 Y 1 R GLU 40  ? CG  ? B GLU 96  CG  
90  1 Y 1 R GLU 40  ? CD  ? B GLU 96  CD  
91  1 Y 1 R GLU 40  ? OE1 ? B GLU 96  OE1 
92  1 Y 1 R GLU 40  ? OE2 ? B GLU 96  OE2 
93  1 Y 1 R GLU 42  ? CG  ? B GLU 98  CG  
94  1 Y 1 R GLU 42  ? CD  ? B GLU 98  CD  
95  1 Y 1 R GLU 42  ? OE1 ? B GLU 98  OE1 
96  1 Y 1 R GLU 42  ? OE2 ? B GLU 98  OE2 
97  1 Y 1 R GLU 45  ? CG  ? B GLU 101 CG  
98  1 Y 1 R GLU 45  ? CD  ? B GLU 101 CD  
99  1 Y 1 R GLU 45  ? OE1 ? B GLU 101 OE1 
100 1 Y 1 R GLU 45  ? OE2 ? B GLU 101 OE2 
101 1 Y 1 R ASN 47  ? CG  ? B ASN 103 CG  
102 1 Y 1 R ASN 47  ? OD1 ? B ASN 103 OD1 
103 1 Y 1 R ASN 47  ? ND2 ? B ASN 103 ND2 
104 1 Y 1 R LYS 48  ? CG  ? B LYS 104 CG  
105 1 Y 1 R LYS 48  ? CD  ? B LYS 104 CD  
106 1 Y 1 R LYS 48  ? CE  ? B LYS 104 CE  
107 1 Y 1 R LYS 48  ? NZ  ? B LYS 104 NZ  
108 1 Y 1 R TYR 49  ? CG  ? B TYR 105 CG  
109 1 Y 1 R TYR 49  ? CD1 ? B TYR 105 CD1 
110 1 Y 1 R TYR 49  ? CD2 ? B TYR 105 CD2 
111 1 Y 1 R TYR 49  ? CE1 ? B TYR 105 CE1 
112 1 Y 1 R TYR 49  ? CE2 ? B TYR 105 CE2 
113 1 Y 1 R TYR 49  ? CZ  ? B TYR 105 CZ  
114 1 Y 1 R TYR 49  ? OH  ? B TYR 105 OH  
115 1 Y 1 R LEU 57  ? CG  ? B LEU 113 CG  
116 1 Y 1 R LEU 57  ? CD1 ? B LEU 113 CD1 
117 1 Y 1 R LEU 57  ? CD2 ? B LEU 113 CD2 
118 1 Y 1 R LEU 60  ? CG  ? B LEU 116 CG  
119 1 Y 1 R LEU 60  ? CD1 ? B LEU 116 CD1 
120 1 Y 1 R LEU 60  ? CD2 ? B LEU 116 CD2 
121 1 Y 1 R LYS 158 ? CG  ? B LYS 214 CG  
122 1 Y 1 R LYS 158 ? CD  ? B LYS 214 CD  
123 1 Y 1 R LYS 158 ? CE  ? B LYS 214 CE  
124 1 Y 1 R LYS 158 ? NZ  ? B LYS 214 NZ  
125 1 Y 1 R LYS 163 ? CG  ? B LYS 219 CG  
126 1 Y 1 R LYS 163 ? CD  ? B LYS 219 CD  
127 1 Y 1 R LYS 163 ? CE  ? B LYS 219 CE  
128 1 Y 1 R LYS 163 ? NZ  ? B LYS 219 NZ  
129 1 Y 1 R LEU 167 ? CG  ? B LEU 223 CG  
130 1 Y 1 R LEU 167 ? CD1 ? B LEU 223 CD1 
131 1 Y 1 R LEU 167 ? CD2 ? B LEU 223 CD2 
132 1 Y 1 R LEU 174 ? CG  ? B LEU 230 CG  
133 1 Y 1 R LEU 174 ? CD1 ? B LEU 230 CD1 
134 1 Y 1 R LEU 174 ? CD2 ? B LEU 230 CD2 
135 1 Y 1 R LEU 228 ? CG  ? B LEU 284 CG  
136 1 Y 1 R LEU 228 ? CD1 ? B LEU 284 CD1 
137 1 Y 1 R LEU 228 ? CD2 ? B LEU 284 CD2 
138 1 Y 1 R LYS 240 ? CG  ? B LYS 296 CG  
139 1 Y 1 R LYS 240 ? CD  ? B LYS 296 CD  
140 1 Y 1 R LYS 240 ? CE  ? B LYS 296 CE  
141 1 Y 1 R LYS 240 ? NZ  ? B LYS 296 NZ  
142 1 Y 1 R LEU 272 ? CG  ? B LEU 328 CG  
143 1 Y 1 R LEU 272 ? CD1 ? B LEU 328 CD1 
144 1 Y 1 R LEU 272 ? CD2 ? B LEU 328 CD2 
145 1 Y 1 R GLN 280 ? CG  ? B GLN 336 CG  
146 1 Y 1 R GLN 280 ? CD  ? B GLN 336 CD  
147 1 Y 1 R GLN 280 ? OE1 ? B GLN 336 OE1 
148 1 Y 1 R GLN 280 ? NE2 ? B GLN 336 NE2 
149 1 Y 1 R GLU 287 ? CG  ? B GLU 343 CG  
150 1 Y 1 R GLU 287 ? CD  ? B GLU 343 CD  
151 1 Y 1 R GLU 287 ? OE1 ? B GLU 343 OE1 
152 1 Y 1 R GLU 287 ? OE2 ? B GLU 343 OE2 
153 1 Y 1 R LYS 320 ? CG  ? B LYS 376 CG  
154 1 Y 1 R LYS 320 ? CD  ? B LYS 376 CD  
155 1 Y 1 R LYS 320 ? CE  ? B LYS 376 CE  
156 1 Y 1 R LYS 320 ? NZ  ? B LYS 376 NZ  
157 1 Y 1 R LEU 326 ? CG  ? B LEU 382 CG  
158 1 Y 1 R LEU 326 ? CD1 ? B LEU 382 CD1 
159 1 Y 1 R LEU 326 ? CD2 ? B LEU 382 CD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XWM 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XWM 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XWM 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8XWM 
_struct.title                        'Structure of CXCR2 bound to CXCL6 (Ligand-receptor focused map)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XWM 
_struct_keywords.text            'GPCR, Arrestin, SIGNALING PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CXCL6_HUMAN P80162 ? 1 GPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN 38 
2 UNP CXCR2_HUMAN P25025 ? 2 
;EDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRS
VTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL
VKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKA
HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKF
RHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
;
2  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XWM D 1  ? 77  ? P80162 38 ? 114 ? 1 77  
2 2 8XWM R 58 ? 416 ? P25025 2  ? 360 ? 2 360 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 8XWM MET R 1  ? UNP P25025 ? ? 'initiating methionine' -55 1  
2 8XWM GLY R 2  ? UNP P25025 ? ? 'expression tag'        -54 2  
2 8XWM LYS R 3  ? UNP P25025 ? ? 'expression tag'        -53 3  
2 8XWM THR R 4  ? UNP P25025 ? ? 'expression tag'        -52 4  
2 8XWM ILE R 5  ? UNP P25025 ? ? 'expression tag'        -51 5  
2 8XWM ILE R 6  ? UNP P25025 ? ? 'expression tag'        -50 6  
2 8XWM ALA R 7  ? UNP P25025 ? ? 'expression tag'        -49 7  
2 8XWM LEU R 8  ? UNP P25025 ? ? 'expression tag'        -48 8  
2 8XWM SER R 9  ? UNP P25025 ? ? 'expression tag'        -47 9  
2 8XWM TYR R 10 ? UNP P25025 ? ? 'expression tag'        -46 10 
2 8XWM ILE R 11 ? UNP P25025 ? ? 'expression tag'        -45 11 
2 8XWM PHE R 12 ? UNP P25025 ? ? 'expression tag'        -44 12 
2 8XWM CYS R 13 ? UNP P25025 ? ? 'expression tag'        -43 13 
2 8XWM LEU R 14 ? UNP P25025 ? ? 'expression tag'        -42 14 
2 8XWM VAL R 15 ? UNP P25025 ? ? 'expression tag'        -41 15 
2 8XWM PHE R 16 ? UNP P25025 ? ? 'expression tag'        -40 16 
2 8XWM ALA R 17 ? UNP P25025 ? ? 'expression tag'        -39 17 
2 8XWM ASP R 18 ? UNP P25025 ? ? 'expression tag'        -38 18 
2 8XWM TYR R 19 ? UNP P25025 ? ? 'expression tag'        -37 19 
2 8XWM LYS R 20 ? UNP P25025 ? ? 'expression tag'        -36 20 
2 8XWM ASP R 21 ? UNP P25025 ? ? 'expression tag'        -35 21 
2 8XWM ASP R 22 ? UNP P25025 ? ? 'expression tag'        -34 22 
2 8XWM ASP R 23 ? UNP P25025 ? ? 'expression tag'        -33 23 
2 8XWM ASP R 24 ? UNP P25025 ? ? 'expression tag'        -32 24 
2 8XWM ALA R 25 ? UNP P25025 ? ? 'expression tag'        -31 25 
2 8XWM ALA R 26 ? UNP P25025 ? ? 'expression tag'        -30 26 
2 8XWM ASN R 27 ? UNP P25025 ? ? 'expression tag'        -29 27 
2 8XWM PHE R 28 ? UNP P25025 ? ? 'expression tag'        -28 28 
2 8XWM THR R 29 ? UNP P25025 ? ? 'expression tag'        -27 29 
2 8XWM PRO R 30 ? UNP P25025 ? ? 'expression tag'        -26 30 
2 8XWM VAL R 31 ? UNP P25025 ? ? 'expression tag'        -25 31 
2 8XWM ASN R 32 ? UNP P25025 ? ? 'expression tag'        -24 32 
2 8XWM GLY R 33 ? UNP P25025 ? ? 'expression tag'        -23 33 
2 8XWM SER R 34 ? UNP P25025 ? ? 'expression tag'        -22 34 
2 8XWM SER R 35 ? UNP P25025 ? ? 'expression tag'        -21 35 
2 8XWM GLY R 36 ? UNP P25025 ? ? 'expression tag'        -20 36 
2 8XWM ASN R 37 ? UNP P25025 ? ? 'expression tag'        -19 37 
2 8XWM GLN R 38 ? UNP P25025 ? ? 'expression tag'        -18 38 
2 8XWM SER R 39 ? UNP P25025 ? ? 'expression tag'        -17 39 
2 8XWM VAL R 40 ? UNP P25025 ? ? 'expression tag'        -16 40 
2 8XWM ARG R 41 ? UNP P25025 ? ? 'expression tag'        -15 41 
2 8XWM LEU R 42 ? UNP P25025 ? ? 'expression tag'        -14 42 
2 8XWM VAL R 43 ? UNP P25025 ? ? 'expression tag'        -13 43 
2 8XWM THR R 44 ? UNP P25025 ? ? 'expression tag'        -12 44 
2 8XWM SER R 45 ? UNP P25025 ? ? 'expression tag'        -11 45 
2 8XWM SER R 46 ? UNP P25025 ? ? 'expression tag'        -10 46 
2 8XWM SER R 47 ? UNP P25025 ? ? 'expression tag'        -9  47 
2 8XWM LEU R 48 ? UNP P25025 ? ? 'expression tag'        -8  48 
2 8XWM GLU R 49 ? UNP P25025 ? ? 'expression tag'        -7  49 
2 8XWM VAL R 50 ? UNP P25025 ? ? 'expression tag'        -6  50 
2 8XWM LEU R 51 ? UNP P25025 ? ? 'expression tag'        -5  51 
2 8XWM PHE R 52 ? UNP P25025 ? ? 'expression tag'        -4  52 
2 8XWM GLN R 53 ? UNP P25025 ? ? 'expression tag'        -3  53 
2 8XWM GLY R 54 ? UNP P25025 ? ? 'expression tag'        -2  54 
2 8XWM PRO R 55 ? UNP P25025 ? ? 'expression tag'        -1  55 
2 8XWM GLY R 56 ? UNP P25025 ? ? 'expression tag'        0   56 
2 8XWM SER R 57 ? UNP P25025 ? ? 'expression tag'        1   57 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN A 22  ? LYS A 24  ? ASN D 22  LYS D 24  5 ? 3  
HELX_P HELX_P2  AA2 ALA A 59  ? ILE A 69  ? ALA D 59  ILE D 69  1 ? 11 
HELX_P HELX_P3  AA3 LEU B 100 ? SER B 132 ? LEU R 44  SER R 76  1 ? 33 
HELX_P HELX_P4  AA4 SER B 137 ? GLY B 167 ? SER R 81  GLY R 111 1 ? 31 
HELX_P HELX_P5  AA5 GLY B 171 ? VAL B 205 ? GLY R 115 VAL R 149 1 ? 35 
HELX_P HELX_P6  AA6 ARG B 209 ? TYR B 216 ? ARG R 153 TYR R 160 5 ? 8  
HELX_P HELX_P7  AA7 LEU B 217 ? PHE B 239 ? LEU R 161 PHE R 183 1 ? 23 
HELX_P HELX_P8  AA8 ASN B 259 ? ILE B 269 ? ASN R 203 ILE R 213 1 ? 11 
HELX_P HELX_P9  AA9 PHE B 276 ? LYS B 296 ? PHE R 220 LYS R 240 1 ? 21 
HELX_P HELX_P10 AB1 GLN B 301 ? THR B 335 ? GLN R 245 THR R 279 1 ? 35 
HELX_P HELX_P11 AB2 THR B 341 ? ILE B 360 ? THR R 285 ILE R 304 1 ? 20 
HELX_P HELX_P12 AB3 LEU B 361 ? ALA B 371 ? LEU R 305 ALA R 315 1 ? 11 
HELX_P HELX_P13 AB4 GLY B 374 ? LEU B 385 ? GLY R 318 LEU R 329 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 12  SG ? ? ? 1_555 A CYS 38  SG ? ? D CYS 12  D CYS 38  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ? ? A CYS 14  SG ? ? ? 1_555 A CYS 54  SG ? ? D CYS 14  D CYS 54  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf3 disulf ? ? B CYS 95  SG ? ? ? 1_555 B CYS 342 SG ? ? R CYS 39  R CYS 286 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf4 disulf ? ? B CYS 175 SG ? ? ? 1_555 B CYS 252 SG ? ? R CYS 119 R CYS 196 1_555 ? ? ? ? ? ? ? 2.035 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 12  ? CYS A 38  ? CYS D 12  ? 1_555 CYS D 38  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 14  ? CYS A 54  ? CYS D 14  ? 1_555 CYS D 54  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 95  ? CYS B 342 ? CYS R 39  ? 1_555 CYS R 286 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 175 ? CYS B 252 ? CYS R 119 ? 1_555 CYS R 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 26  ? PHE A 32  ? ILE D 26  PHE D 32  
AA1 2 GLU A 42  ? LEU A 47  ? GLU D 42  LEU D 47  
AA1 3 GLN A 52  ? LEU A 55  ? GLN D 52  LEU D 55  
AA2 1 ARG B 240 ? VAL B 243 ? ARG R 184 VAL R 187 
AA2 2 ALA B 251 ? GLU B 254 ? ALA R 195 GLU R 198 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N PHE A 32  ? N PHE D 32  O GLU A 42  ? O GLU D 42  
AA1 2 3 N VAL A 43  ? N VAL D 43  O LEU A 55  ? O LEU D 55  
AA2 1 2 N ARG B 241 ? N ARG R 185 O TYR B 253 ? O TYR R 197 
# 
_pdbx_entry_details.entry_id                   8XWM 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE R 220 ? ? -131.27 -39.18 
2 1 LYS R 240 ? ? -91.54  31.08  
3 1 LEU R 305 ? ? -64.57  0.04   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8XWM 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   SwissModel 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    8XWM 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.71 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               61539 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 RECOMBINANT COMPLEX 'C-X-C chemokine receptor type 2 in complex with C-X-C motif chemokine 6' ? ? ? '1, 2' 
2 1 RECOMBINANT COMPLEX 'C-X-C chemokine receptor type 2'                                         ? ? ? 2      
3 1 RECOMBINANT COMPLEX 'C-X-C motif chemokine 6'                                                 ? ? ? 1      
# 
_em_image_scans.entry_id                8XWM 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        40 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8XWM 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              8XWM 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8XWM 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 D GLY 1   ? A GLY 1   
2   1 Y 1 D PRO 2   ? A PRO 2   
3   1 Y 1 D VAL 3   ? A VAL 3   
4   1 Y 1 D SER 4   ? A SER 4   
5   1 Y 1 D LEU 70  ? A LEU 70  
6   1 Y 1 D ASP 71  ? A ASP 71  
7   1 Y 1 D SER 72  ? A SER 72  
8   1 Y 1 D GLY 73  ? A GLY 73  
9   1 Y 1 D ASN 74  ? A ASN 74  
10  1 Y 1 D LYS 75  ? A LYS 75  
11  1 Y 1 D LYS 76  ? A LYS 76  
12  1 Y 1 D ASN 77  ? A ASN 77  
13  1 Y 1 R MET -55 ? B MET 1   
14  1 Y 1 R GLY -54 ? B GLY 2   
15  1 Y 1 R LYS -53 ? B LYS 3   
16  1 Y 1 R THR -52 ? B THR 4   
17  1 Y 1 R ILE -51 ? B ILE 5   
18  1 Y 1 R ILE -50 ? B ILE 6   
19  1 Y 1 R ALA -49 ? B ALA 7   
20  1 Y 1 R LEU -48 ? B LEU 8   
21  1 Y 1 R SER -47 ? B SER 9   
22  1 Y 1 R TYR -46 ? B TYR 10  
23  1 Y 1 R ILE -45 ? B ILE 11  
24  1 Y 1 R PHE -44 ? B PHE 12  
25  1 Y 1 R CYS -43 ? B CYS 13  
26  1 Y 1 R LEU -42 ? B LEU 14  
27  1 Y 1 R VAL -41 ? B VAL 15  
28  1 Y 1 R PHE -40 ? B PHE 16  
29  1 Y 1 R ALA -39 ? B ALA 17  
30  1 Y 1 R ASP -38 ? B ASP 18  
31  1 Y 1 R TYR -37 ? B TYR 19  
32  1 Y 1 R LYS -36 ? B LYS 20  
33  1 Y 1 R ASP -35 ? B ASP 21  
34  1 Y 1 R ASP -34 ? B ASP 22  
35  1 Y 1 R ASP -33 ? B ASP 23  
36  1 Y 1 R ASP -32 ? B ASP 24  
37  1 Y 1 R ALA -31 ? B ALA 25  
38  1 Y 1 R ALA -30 ? B ALA 26  
39  1 Y 1 R ASN -29 ? B ASN 27  
40  1 Y 1 R PHE -28 ? B PHE 28  
41  1 Y 1 R THR -27 ? B THR 29  
42  1 Y 1 R PRO -26 ? B PRO 30  
43  1 Y 1 R VAL -25 ? B VAL 31  
44  1 Y 1 R ASN -24 ? B ASN 32  
45  1 Y 1 R GLY -23 ? B GLY 33  
46  1 Y 1 R SER -22 ? B SER 34  
47  1 Y 1 R SER -21 ? B SER 35  
48  1 Y 1 R GLY -20 ? B GLY 36  
49  1 Y 1 R ASN -19 ? B ASN 37  
50  1 Y 1 R GLN -18 ? B GLN 38  
51  1 Y 1 R SER -17 ? B SER 39  
52  1 Y 1 R VAL -16 ? B VAL 40  
53  1 Y 1 R ARG -15 ? B ARG 41  
54  1 Y 1 R LEU -14 ? B LEU 42  
55  1 Y 1 R VAL -13 ? B VAL 43  
56  1 Y 1 R THR -12 ? B THR 44  
57  1 Y 1 R SER -11 ? B SER 45  
58  1 Y 1 R SER -10 ? B SER 46  
59  1 Y 1 R SER -9  ? B SER 47  
60  1 Y 1 R LEU -8  ? B LEU 48  
61  1 Y 1 R GLU -7  ? B GLU 49  
62  1 Y 1 R VAL -6  ? B VAL 50  
63  1 Y 1 R LEU -5  ? B LEU 51  
64  1 Y 1 R PHE -4  ? B PHE 52  
65  1 Y 1 R GLN -3  ? B GLN 53  
66  1 Y 1 R GLY -2  ? B GLY 54  
67  1 Y 1 R PRO -1  ? B PRO 55  
68  1 Y 1 R GLY 0   ? B GLY 56  
69  1 Y 1 R SER 1   ? B SER 57  
70  1 Y 1 R GLU 2   ? B GLU 58  
71  1 Y 1 R ASP 3   ? B ASP 59  
72  1 Y 1 R PHE 4   ? B PHE 60  
73  1 Y 1 R ASN 5   ? B ASN 61  
74  1 Y 1 R MET 6   ? B MET 62  
75  1 Y 1 R GLU 7   ? B GLU 63  
76  1 Y 1 R SER 8   ? B SER 64  
77  1 Y 1 R ASP 9   ? B ASP 65  
78  1 Y 1 R SER 10  ? B SER 66  
79  1 Y 1 R PHE 11  ? B PHE 67  
80  1 Y 1 R GLU 12  ? B GLU 68  
81  1 Y 1 R ASP 13  ? B ASP 69  
82  1 Y 1 R PHE 14  ? B PHE 70  
83  1 Y 1 R TRP 15  ? B TRP 71  
84  1 Y 1 R LYS 16  ? B LYS 72  
85  1 Y 1 R GLY 17  ? B GLY 73  
86  1 Y 1 R GLU 18  ? B GLU 74  
87  1 Y 1 R ASP 19  ? B ASP 75  
88  1 Y 1 R LEU 20  ? B LEU 76  
89  1 Y 1 R SER 21  ? B SER 77  
90  1 Y 1 R ASN 22  ? B ASN 78  
91  1 Y 1 R TYR 23  ? B TYR 79  
92  1 Y 1 R SER 24  ? B SER 80  
93  1 Y 1 R TYR 25  ? B TYR 81  
94  1 Y 1 R SER 26  ? B SER 82  
95  1 Y 1 R SER 27  ? B SER 83  
96  1 Y 1 R THR 28  ? B THR 84  
97  1 Y 1 R LEU 29  ? B LEU 85  
98  1 Y 1 R PRO 30  ? B PRO 86  
99  1 Y 1 R PRO 31  ? B PRO 87  
100 1 Y 1 R PHE 32  ? B PHE 88  
101 1 Y 1 R ILE 331 ? B ILE 387 
102 1 Y 1 R HIS 332 ? B HIS 388 
103 1 Y 1 R GLY 333 ? B GLY 389 
104 1 Y 1 R LEU 334 ? B LEU 390 
105 1 Y 1 R ILE 335 ? B ILE 391 
106 1 Y 1 R SER 336 ? B SER 392 
107 1 Y 1 R LYS 337 ? B LYS 393 
108 1 Y 1 R ASP 338 ? B ASP 394 
109 1 Y 1 R SER 339 ? B SER 395 
110 1 Y 1 R LEU 340 ? B LEU 396 
111 1 Y 1 R PRO 341 ? B PRO 397 
112 1 Y 1 R LYS 342 ? B LYS 398 
113 1 Y 1 R ASP 343 ? B ASP 399 
114 1 Y 1 R SER 344 ? B SER 400 
115 1 Y 1 R ARG 345 ? B ARG 401 
116 1 Y 1 R PRO 346 ? B PRO 402 
117 1 Y 1 R SER 347 ? B SER 403 
118 1 Y 1 R PHE 348 ? B PHE 404 
119 1 Y 1 R VAL 349 ? B VAL 405 
120 1 Y 1 R GLY 350 ? B GLY 406 
121 1 Y 1 R SER 351 ? B SER 407 
122 1 Y 1 R SER 352 ? B SER 408 
123 1 Y 1 R SER 353 ? B SER 409 
124 1 Y 1 R GLY 354 ? B GLY 410 
125 1 Y 1 R HIS 355 ? B HIS 411 
126 1 Y 1 R THR 356 ? B THR 412 
127 1 Y 1 R SER 357 ? B SER 413 
128 1 Y 1 R THR 358 ? B THR 414 
129 1 Y 1 R THR 359 ? B THR 415 
130 1 Y 1 R LEU 360 ? B LEU 416 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-16 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8XWM 
_em_admin.last_update        2025-04-09 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'Structure of CXCR2 bound to CXCL6 (Ligand-receptor focused map)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
loop_
_em_entity_assembly_molwt.entity_assembly_id 
_em_entity_assembly_molwt.experimental_flag 
_em_entity_assembly_molwt.id 
_em_entity_assembly_molwt.units 
_em_entity_assembly_molwt.value 
1 NO 1 ? ? 
1 NO 2 ? ? 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 9606 'Homo sapiens' ? ? ? ? ? 
? ? 2 3 9606 'Homo sapiens' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 1 2 7108 'Spodoptera frugiperda' ? ? 
? 2 3 562  'Escherichia coli'      ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1609421 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ?   
MASKING                    ? 3  ? ? ? ?         ?   
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC 4.4 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?   
'MODEL FITTING'            ? 7  ? 1 ? Coot      ?   
OTHER                      ? 8  ? ? ? ?         ?   
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    ?   
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?         ?   
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?         ?   
CLASSIFICATION             ? 12 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION             ? 14 1 ? ? RELION    4   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Science and Engineering Research Board (SERB)' 
_pdbx_audit_support.country                India 
_pdbx_audit_support.grant_number           IPA/2020/000405 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      SwissModel 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    8XWM 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 5   ? 104.683 135.642 78.509  1.00 111.78 ? 5   ALA D N   1 
ATOM 2    C CA  . ALA A 1 5   ? 105.382 134.348 78.381  1.00 111.78 ? 5   ALA D CA  1 
ATOM 3    C C   . ALA A 1 5   ? 105.901 133.981 79.751  1.00 111.78 ? 5   ALA D C   1 
ATOM 4    O O   . ALA A 1 5   ? 105.191 134.244 80.697  1.00 111.78 ? 5   ALA D O   1 
ATOM 5    C CB  . ALA A 1 5   ? 106.515 134.493 77.420  1.00 111.78 ? 5   ALA D CB  1 
ATOM 6    N N   . VAL A 1 6   ? 107.042 133.313 79.840  1.00 112.87 ? 6   VAL D N   1 
ATOM 7    C CA  . VAL A 1 6   ? 107.630 133.106 81.158  1.00 112.87 ? 6   VAL D CA  1 
ATOM 8    C C   . VAL A 1 6   ? 109.137 133.234 81.017  1.00 112.87 ? 6   VAL D C   1 
ATOM 9    O O   . VAL A 1 6   ? 109.735 132.674 80.096  1.00 112.87 ? 6   VAL D O   1 
ATOM 10   C CB  . VAL A 1 6   ? 107.231 131.733 81.746  1.00 112.87 ? 6   VAL D CB  1 
ATOM 11   C CG1 . VAL A 1 6   ? 107.861 131.541 83.117  1.00 112.87 ? 6   VAL D CG1 1 
ATOM 12   C CG2 . VAL A 1 6   ? 105.720 131.606 81.821  1.00 112.87 ? 6   VAL D CG2 1 
ATOM 13   N N   . LEU A 1 7   ? 109.750 133.967 81.942  1.00 112.91 ? 7   LEU D N   1 
ATOM 14   C CA  . LEU A 1 7   ? 111.189 134.178 81.890  1.00 112.91 ? 7   LEU D CA  1 
ATOM 15   C C   . LEU A 1 7   ? 111.672 134.659 83.248  1.00 112.91 ? 7   LEU D C   1 
ATOM 16   O O   . LEU A 1 7   ? 110.978 135.423 83.922  1.00 112.91 ? 7   LEU D O   1 
ATOM 17   C CB  . LEU A 1 7   ? 111.556 135.202 80.807  1.00 112.91 ? 7   LEU D CB  1 
ATOM 18   C CG  . LEU A 1 7   ? 111.735 134.712 79.365  1.00 112.91 ? 7   LEU D CG  1 
ATOM 19   C CD1 . LEU A 1 7   ? 112.405 135.788 78.527  1.00 112.91 ? 7   LEU D CD1 1 
ATOM 20   C CD2 . LEU A 1 7   ? 112.541 133.428 79.301  1.00 112.91 ? 7   LEU D CD2 1 
ATOM 21   N N   . THR A 1 8   ? 112.864 134.205 83.638  1.00 112.18 ? 8   THR D N   1 
ATOM 22   C CA  . THR A 1 8   ? 113.502 134.657 84.867  1.00 112.18 ? 8   THR D CA  1 
ATOM 23   C C   . THR A 1 8   ? 114.753 135.483 84.618  1.00 112.18 ? 8   THR D C   1 
ATOM 24   O O   . THR A 1 8   ? 115.212 136.173 85.535  1.00 112.18 ? 8   THR D O   1 
ATOM 25   C CB  . THR A 1 8   ? 113.875 133.464 85.753  1.00 112.18 ? 8   THR D CB  1 
ATOM 26   O OG1 . THR A 1 8   ? 114.700 133.913 86.835  1.00 112.18 ? 8   THR D OG1 1 
ATOM 27   C CG2 . THR A 1 8   ? 114.622 132.409 84.953  1.00 112.18 ? 8   THR D CG2 1 
ATOM 28   N N   . GLU A 1 9   ? 115.319 135.417 83.416  1.00 112.35 ? 9   GLU D N   1 
ATOM 29   C CA  . GLU A 1 9   ? 116.465 136.233 83.029  1.00 112.35 ? 9   GLU D CA  1 
ATOM 30   C C   . GLU A 1 9   ? 116.125 136.919 81.714  1.00 112.35 ? 9   GLU D C   1 
ATOM 31   O O   . GLU A 1 9   ? 116.221 136.306 80.647  1.00 112.35 ? 9   GLU D O   1 
ATOM 32   C CB  . GLU A 1 9   ? 117.729 135.385 82.894  1.00 112.35 ? 9   GLU D CB  1 
ATOM 33   C CG  . GLU A 1 9   ? 118.275 134.878 84.218  1.00 112.35 ? 9   GLU D CG  1 
ATOM 34   C CD  . GLU A 1 9   ? 119.198 135.871 84.894  1.00 112.35 ? 9   GLU D CD  1 
ATOM 35   O OE1 . GLU A 1 9   ? 119.327 137.007 84.393  1.00 112.35 ? 9   GLU D OE1 1 
ATOM 36   O OE2 . GLU A 1 9   ? 119.798 135.512 85.928  1.00 112.35 ? 9   GLU D OE2 1 
ATOM 37   N N   . LEU A 1 10  ? 115.727 138.184 81.791  1.00 112.71 ? 10  LEU D N   1 
ATOM 38   C CA  . LEU A 1 10  ? 115.346 138.946 80.612  1.00 112.71 ? 10  LEU D CA  1 
ATOM 39   C C   . LEU A 1 10  ? 116.590 139.298 79.811  1.00 112.71 ? 10  LEU D C   1 
ATOM 40   O O   . LEU A 1 10  ? 117.642 139.604 80.378  1.00 112.71 ? 10  LEU D O   1 
ATOM 41   C CB  . LEU A 1 10  ? 114.592 140.216 81.006  1.00 112.71 ? 10  LEU D CB  1 
ATOM 42   C CG  . LEU A 1 10  ? 113.701 140.110 82.245  1.00 112.71 ? 10  LEU D CG  1 
ATOM 43   C CD1 . LEU A 1 10  ? 112.929 141.395 82.455  1.00 112.71 ? 10  LEU D CD1 1 
ATOM 44   C CD2 . LEU A 1 10  ? 112.754 138.933 82.120  1.00 112.71 ? 10  LEU D CD2 1 
ATOM 45   N N   . ARG A 1 11  ? 116.463 139.253 78.487  1.00 121.23 ? 11  ARG D N   1 
ATOM 46   C CA  . ARG A 1 11  ? 117.600 139.401 77.593  1.00 121.23 ? 11  ARG D CA  1 
ATOM 47   C C   . ARG A 1 11  ? 117.183 140.204 76.367  1.00 121.23 ? 11  ARG D C   1 
ATOM 48   O O   . ARG A 1 11  ? 115.996 140.405 76.100  1.00 121.23 ? 11  ARG D O   1 
ATOM 49   C CB  . ARG A 1 11  ? 118.151 138.026 77.191  1.00 121.23 ? 11  ARG D CB  1 
ATOM 50   C CG  . ARG A 1 11  ? 119.658 137.981 77.000  1.00 121.23 ? 11  ARG D CG  1 
ATOM 51   C CD  . ARG A 1 11  ? 120.241 136.639 77.429  1.00 121.23 ? 11  ARG D CD  1 
ATOM 52   N NE  . ARG A 1 11  ? 119.332 135.526 77.167  1.00 121.23 ? 11  ARG D NE  1 
ATOM 53   C CZ  . ARG A 1 11  ? 118.795 134.742 78.095  1.00 121.23 ? 11  ARG D CZ  1 
ATOM 54   N NH1 . ARG A 1 11  ? 119.055 134.906 79.383  1.00 121.23 ? 11  ARG D NH1 1 
ATOM 55   N NH2 . ARG A 1 11  ? 117.975 133.764 77.722  1.00 121.23 ? 11  ARG D NH2 1 
ATOM 56   N N   . CYS A 1 12  ? 118.181 140.669 75.618  1.00 130.98 ? 12  CYS D N   1 
ATOM 57   C CA  . CYS A 1 12  ? 117.919 141.523 74.470  1.00 130.98 ? 12  CYS D CA  1 
ATOM 58   C C   . CYS A 1 12  ? 117.147 140.761 73.397  1.00 130.98 ? 12  CYS D C   1 
ATOM 59   O O   . CYS A 1 12  ? 117.253 139.540 73.261  1.00 130.98 ? 12  CYS D O   1 
ATOM 60   C CB  . CYS A 1 12  ? 119.228 142.060 73.891  1.00 130.98 ? 12  CYS D CB  1 
ATOM 61   S SG  . CYS A 1 12  ? 120.113 143.207 74.975  1.00 130.98 ? 12  CYS D SG  1 
ATOM 62   N N   . THR A 1 13  ? 116.359 141.509 72.626  1.00 138.61 ? 13  THR D N   1 
ATOM 63   C CA  . THR A 1 13  ? 115.489 140.941 71.605  1.00 138.61 ? 13  THR D CA  1 
ATOM 64   C C   . THR A 1 13  ? 116.200 140.730 70.274  1.00 138.61 ? 13  THR D C   1 
ATOM 65   O O   . THR A 1 13  ? 115.650 140.065 69.390  1.00 138.61 ? 13  THR D O   1 
ATOM 66   C CB  . THR A 1 13  ? 114.267 141.842 71.401  1.00 138.61 ? 13  THR D CB  1 
ATOM 67   O OG1 . THR A 1 13  ? 113.625 142.075 72.661  1.00 138.61 ? 13  THR D OG1 1 
ATOM 68   C CG2 . THR A 1 13  ? 113.273 141.196 70.447  1.00 138.61 ? 13  THR D CG2 1 
ATOM 69   N N   . CYS A 1 14  ? 117.407 141.267 70.110  1.00 142.29 ? 14  CYS D N   1 
ATOM 70   C CA  . CYS A 1 14  ? 118.143 141.117 68.863  1.00 142.29 ? 14  CYS D CA  1 
ATOM 71   C C   . CYS A 1 14  ? 119.612 140.882 69.175  1.00 142.29 ? 14  CYS D C   1 
ATOM 72   O O   . CYS A 1 14  ? 120.167 141.500 70.087  1.00 142.29 ? 14  CYS D O   1 
ATOM 73   C CB  . CYS A 1 14  ? 117.992 142.350 67.967  1.00 142.29 ? 14  CYS D CB  1 
ATOM 74   S SG  . CYS A 1 14  ? 116.295 142.696 67.451  1.00 142.29 ? 14  CYS D SG  1 
ATOM 75   N N   . LEU A 1 15  ? 120.234 139.989 68.407  1.00 137.78 ? 15  LEU D N   1 
ATOM 76   C CA  . LEU A 1 15  ? 121.655 139.701 68.542  1.00 137.78 ? 15  LEU D CA  1 
ATOM 77   C C   . LEU A 1 15  ? 122.508 140.419 67.510  1.00 137.78 ? 15  LEU D C   1 
ATOM 78   O O   . LEU A 1 15  ? 123.633 140.820 67.825  1.00 137.78 ? 15  LEU D O   1 
ATOM 79   C CB  . LEU A 1 15  ? 121.905 138.193 68.422  1.00 137.78 ? 15  LEU D CB  1 
ATOM 80   C CG  . LEU A 1 15  ? 121.234 137.290 69.458  1.00 137.78 ? 15  LEU D CG  1 
ATOM 81   C CD1 . LEU A 1 15  ? 121.873 135.913 69.437  1.00 137.78 ? 15  LEU D CD1 1 
ATOM 82   C CD2 . LEU A 1 15  ? 121.311 137.891 70.851  1.00 137.78 ? 15  LEU D CD2 1 
ATOM 83   N N   . ARG A 1 16  ? 122.003 140.589 66.291  1.00 151.27 ? 16  ARG D N   1 
ATOM 84   C CA  . ARG A 1 16  ? 122.748 141.240 65.226  1.00 151.27 ? 16  ARG D CA  1 
ATOM 85   C C   . ARG A 1 16  ? 121.813 142.168 64.466  1.00 151.27 ? 16  ARG D C   1 
ATOM 86   O O   . ARG A 1 16  ? 120.590 142.015 64.496  1.00 151.27 ? 16  ARG D O   1 
ATOM 87   C CB  . ARG A 1 16  ? 123.385 140.212 64.282  1.00 151.27 ? 16  ARG D CB  1 
ATOM 88   C CG  . ARG A 1 16  ? 124.269 139.209 65.004  1.00 151.27 ? 16  ARG D CG  1 
ATOM 89   C CD  . ARG A 1 16  ? 125.316 138.603 64.088  1.00 151.27 ? 16  ARG D CD  1 
ATOM 90   N NE  . ARG A 1 16  ? 126.406 137.997 64.844  1.00 151.27 ? 16  ARG D NE  1 
ATOM 91   C CZ  . ARG A 1 16  ? 127.415 137.328 64.303  1.00 151.27 ? 16  ARG D CZ  1 
ATOM 92   N NH1 . ARG A 1 16  ? 127.507 137.153 62.995  1.00 151.27 ? 16  ARG D NH1 1 
ATOM 93   N NH2 . ARG A 1 16  ? 128.357 136.823 65.095  1.00 151.27 ? 16  ARG D NH2 1 
ATOM 94   N N   . VAL A 1 17  ? 122.409 143.140 63.778  1.00 159.74 ? 17  VAL D N   1 
ATOM 95   C CA  . VAL A 1 17  ? 121.674 144.228 63.153  1.00 159.74 ? 17  VAL D CA  1 
ATOM 96   C C   . VAL A 1 17  ? 121.767 144.087 61.636  1.00 159.74 ? 17  VAL D C   1 
ATOM 97   O O   . VAL A 1 17  ? 122.720 143.526 61.095  1.00 159.74 ? 17  VAL D O   1 
ATOM 98   C CB  . VAL A 1 17  ? 122.192 145.606 63.606  1.00 159.74 ? 17  VAL D CB  1 
ATOM 99   C CG1 . VAL A 1 17  ? 121.436 146.716 62.905  1.00 159.74 ? 17  VAL D CG1 1 
ATOM 100  C CG2 . VAL A 1 17  ? 122.075 145.746 65.117  1.00 159.74 ? 17  VAL D CG2 1 
ATOM 101  N N   . THR A 1 18  ? 120.750 144.611 60.955  1.00 163.64 ? 18  THR D N   1 
ATOM 102  C CA  . THR A 1 18  ? 120.673 144.603 59.500  1.00 163.64 ? 18  THR D CA  1 
ATOM 103  C C   . THR A 1 18  ? 120.679 146.035 58.988  1.00 163.64 ? 18  THR D C   1 
ATOM 104  O O   . THR A 1 18  ? 119.900 146.870 59.459  1.00 163.64 ? 18  THR D O   1 
ATOM 105  C CB  . THR A 1 18  ? 119.433 143.860 59.026  1.00 30.00  ? 18  THR D CB  1 
ATOM 106  N N   . LEU A 1 19  ? 121.558 146.313 58.027  1.00 161.55 ? 19  LEU D N   1 
ATOM 107  C CA  . LEU A 1 19  ? 121.617 147.608 57.367  1.00 161.55 ? 19  LEU D CA  1 
ATOM 108  C C   . LEU A 1 19  ? 121.132 147.558 55.925  1.00 161.55 ? 19  LEU D C   1 
ATOM 109  O O   . LEU A 1 19  ? 121.242 148.562 55.214  1.00 161.55 ? 19  LEU D O   1 
ATOM 110  C CB  . LEU A 1 19  ? 123.036 148.154 57.421  1.00 30.00  ? 19  LEU D CB  1 
ATOM 111  N N   . ARG A 1 20  ? 120.600 146.422 55.475  1.00 165.03 ? 20  ARG D N   1 
ATOM 112  C CA  . ARG A 1 20  ? 120.139 146.237 54.100  1.00 165.03 ? 20  ARG D CA  1 
ATOM 113  C C   . ARG A 1 20  ? 118.645 145.926 54.143  1.00 165.03 ? 20  ARG D C   1 
ATOM 114  O O   . ARG A 1 20  ? 118.251 144.783 54.392  1.00 165.03 ? 20  ARG D O   1 
ATOM 115  C CB  . ARG A 1 20  ? 120.915 145.131 53.402  1.00 30.00  ? 20  ARG D CB  1 
ATOM 116  N N   . VAL A 1 21  ? 117.815 146.939 53.897  1.00 169.25 ? 21  VAL D N   1 
ATOM 117  C CA  . VAL A 1 21  ? 116.366 146.781 53.955  1.00 169.25 ? 21  VAL D CA  1 
ATOM 118  C C   . VAL A 1 21  ? 115.736 147.832 53.055  1.00 169.25 ? 21  VAL D C   1 
ATOM 119  O O   . VAL A 1 21  ? 116.298 148.908 52.842  1.00 169.25 ? 21  VAL D O   1 
ATOM 120  C CB  . VAL A 1 21  ? 115.849 146.899 55.412  1.00 169.25 ? 21  VAL D CB  1 
ATOM 121  C CG1 . VAL A 1 21  ? 116.340 148.192 56.050  1.00 169.25 ? 21  VAL D CG1 1 
ATOM 122  C CG2 . VAL A 1 21  ? 114.329 146.818 55.452  1.00 169.25 ? 21  VAL D CG2 1 
ATOM 123  N N   . ASN A 1 22  ? 114.554 147.517 52.522  1.00 171.35 ? 22  ASN D N   1 
ATOM 124  C CA  . ASN A 1 22  ? 113.796 148.434 51.686  1.00 171.35 ? 22  ASN D CA  1 
ATOM 125  C C   . ASN A 1 22  ? 112.572 148.928 52.441  1.00 171.35 ? 22  ASN D C   1 
ATOM 126  O O   . ASN A 1 22  ? 111.841 148.109 53.014  1.00 171.35 ? 22  ASN D O   1 
ATOM 127  C CB  . ASN A 1 22  ? 113.363 147.749 50.386  1.00 171.35 ? 22  ASN D CB  1 
ATOM 128  C CG  . ASN A 1 22  ? 112.746 148.716 49.397  1.00 171.35 ? 22  ASN D CG  1 
ATOM 129  O OD1 . ASN A 1 22  ? 113.395 149.660 48.946  1.00 171.35 ? 22  ASN D OD1 1 
ATOM 130  N ND2 . ASN A 1 22  ? 111.484 148.486 49.053  1.00 171.35 ? 22  ASN D ND2 1 
ATOM 131  N N   . PRO A 1 23  ? 112.307 150.240 52.473  1.00 171.83 ? 23  PRO D N   1 
ATOM 132  C CA  . PRO A 1 23  ? 111.146 150.718 53.245  1.00 171.83 ? 23  PRO D CA  1 
ATOM 133  C C   . PRO A 1 23  ? 109.828 150.105 52.805  1.00 171.83 ? 23  PRO D C   1 
ATOM 134  O O   . PRO A 1 23  ? 108.953 149.861 53.645  1.00 171.83 ? 23  PRO D O   1 
ATOM 135  C CB  . PRO A 1 23  ? 111.172 152.236 53.008  1.00 171.83 ? 23  PRO D CB  1 
ATOM 136  C CG  . PRO A 1 23  ? 112.576 152.543 52.635  1.00 171.83 ? 23  PRO D CG  1 
ATOM 137  C CD  . PRO A 1 23  ? 113.059 151.354 51.869  1.00 171.83 ? 23  PRO D CD  1 
ATOM 138  N N   . LYS A 1 24  ? 109.659 149.847 51.506  1.00 171.01 ? 24  LYS D N   1 
ATOM 139  C CA  . LYS A 1 24  ? 108.379 149.341 51.018  1.00 171.01 ? 24  LYS D CA  1 
ATOM 140  C C   . LYS A 1 24  ? 108.079 147.957 51.579  1.00 171.01 ? 24  LYS D C   1 
ATOM 141  O O   . LYS A 1 24  ? 106.927 147.650 51.905  1.00 171.01 ? 24  LYS D O   1 
ATOM 142  C CB  . LYS A 1 24  ? 108.367 149.311 49.497  1.00 30.00  ? 24  LYS D CB  1 
ATOM 143  N N   . THR A 1 25  ? 109.099 147.109 51.701  1.00 169.63 ? 25  THR D N   1 
ATOM 144  C CA  . THR A 1 25  ? 108.903 145.751 52.193  1.00 169.63 ? 25  THR D CA  1 
ATOM 145  C C   . THR A 1 25  ? 108.562 145.698 53.676  1.00 169.63 ? 25  THR D C   1 
ATOM 146  O O   . THR A 1 25  ? 108.187 144.627 54.165  1.00 169.63 ? 25  THR D O   1 
ATOM 147  C CB  . THR A 1 25  ? 110.156 144.914 51.931  1.00 169.63 ? 25  THR D CB  1 
ATOM 148  O OG1 . THR A 1 25  ? 111.270 145.483 52.632  1.00 169.63 ? 25  THR D OG1 1 
ATOM 149  C CG2 . THR A 1 25  ? 110.467 144.864 50.441  1.00 169.63 ? 25  THR D CG2 1 
ATOM 150  N N   . ILE A 1 26  ? 108.674 146.809 54.398  1.00 169.54 ? 26  ILE D N   1 
ATOM 151  C CA  . ILE A 1 26  ? 108.413 146.837 55.833  1.00 169.54 ? 26  ILE D CA  1 
ATOM 152  C C   . ILE A 1 26  ? 106.912 146.940 56.060  1.00 169.54 ? 26  ILE D C   1 
ATOM 153  O O   . ILE A 1 26  ? 106.248 147.824 55.505  1.00 169.54 ? 26  ILE D O   1 
ATOM 154  C CB  . ILE A 1 26  ? 109.147 147.991 56.499  1.00 30.00  ? 26  ILE D CB  1 
ATOM 155  N N   . GLY A 1 27  ? 106.377 146.037 56.878  1.00 167.84 ? 27  GLY D N   1 
ATOM 156  C CA  . GLY A 1 27  ? 104.961 146.038 57.188  1.00 167.84 ? 27  GLY D CA  1 
ATOM 157  C C   . GLY A 1 27  ? 104.644 146.707 58.509  1.00 167.84 ? 27  GLY D C   1 
ATOM 158  O O   . GLY A 1 27  ? 103.731 147.534 58.591  1.00 167.84 ? 27  GLY D O   1 
ATOM 159  N N   . LYS A 1 28  ? 105.393 146.356 59.552  1.00 163.89 ? 28  LYS D N   1 
ATOM 160  C CA  . LYS A 1 28  ? 105.194 146.919 60.879  1.00 163.89 ? 28  LYS D CA  1 
ATOM 161  C C   . LYS A 1 28  ? 106.544 147.303 61.464  1.00 163.89 ? 28  LYS D C   1 
ATOM 162  O O   . LYS A 1 28  ? 107.562 146.673 61.170  1.00 163.89 ? 28  LYS D O   1 
ATOM 163  C CB  . LYS A 1 28  ? 104.466 145.936 61.784  1.00 30.00  ? 28  LYS D CB  1 
ATOM 164  N N   . LEU A 1 29  ? 106.545 148.342 62.296  1.00 161.02 ? 29  LEU D N   1 
ATOM 165  C CA  . LEU A 1 29  ? 107.758 148.822 62.946  1.00 161.02 ? 29  LEU D CA  1 
ATOM 166  C C   . LEU A 1 29  ? 107.495 148.986 64.435  1.00 161.02 ? 29  LEU D C   1 
ATOM 167  O O   . LEU A 1 29  ? 106.465 149.542 64.828  1.00 161.02 ? 29  LEU D O   1 
ATOM 168  C CB  . LEU A 1 29  ? 108.225 150.131 62.327  1.00 30.00  ? 29  LEU D CB  1 
ATOM 169  N N   . GLN A 1 30  ? 108.426 148.504 65.257  1.00 159.69 ? 30  GLN D N   1 
ATOM 170  C CA  . GLN A 1 30  ? 108.318 148.597 66.705  1.00 159.69 ? 30  GLN D CA  1 
ATOM 171  C C   . GLN A 1 30  ? 109.652 149.038 67.286  1.00 159.69 ? 30  GLN D C   1 
ATOM 172  O O   . GLN A 1 30  ? 110.715 148.691 66.760  1.00 159.69 ? 30  GLN D O   1 
ATOM 173  C CB  . GLN A 1 30  ? 107.878 147.269 67.302  1.00 30.00  ? 30  GLN D CB  1 
ATOM 174  N N   . VAL A 1 31  ? 109.587 149.806 68.371  1.00 153.87 ? 31  VAL D N   1 
ATOM 175  C CA  . VAL A 1 31  ? 110.763 150.358 69.030  1.00 153.87 ? 31  VAL D CA  1 
ATOM 176  C C   . VAL A 1 31  ? 110.768 149.895 70.478  1.00 153.87 ? 31  VAL D C   1 
ATOM 177  O O   . VAL A 1 31  ? 109.773 150.061 71.192  1.00 153.87 ? 31  VAL D O   1 
ATOM 178  C CB  . VAL A 1 31  ? 110.787 151.896 68.958  1.00 153.87 ? 31  VAL D CB  1 
ATOM 179  C CG1 . VAL A 1 31  ? 112.140 152.425 69.406  1.00 153.87 ? 31  VAL D CG1 1 
ATOM 180  C CG2 . VAL A 1 31  ? 110.457 152.366 67.551  1.00 153.87 ? 31  VAL D CG2 1 
ATOM 181  N N   . PHE A 1 32  ? 111.885 149.313 70.906  1.00 143.17 ? 32  PHE D N   1 
ATOM 182  C CA  . PHE A 1 32  ? 112.103 148.941 72.289  1.00 143.17 ? 32  PHE D CA  1 
ATOM 183  C C   . PHE A 1 32  ? 113.183 149.830 72.883  1.00 143.17 ? 32  PHE D C   1 
ATOM 184  O O   . PHE A 1 32  ? 114.357 149.696 72.508  1.00 143.17 ? 32  PHE D O   1 
ATOM 185  C CB  . PHE A 1 32  ? 112.522 147.473 72.394  1.00 143.17 ? 32  PHE D CB  1 
ATOM 186  C CG  . PHE A 1 32  ? 111.597 146.530 71.684  1.00 143.17 ? 32  PHE D CG  1 
ATOM 187  C CD1 . PHE A 1 32  ? 110.488 146.010 72.326  1.00 143.17 ? 32  PHE D CD1 1 
ATOM 188  C CD2 . PHE A 1 32  ? 111.836 146.167 70.370  1.00 143.17 ? 32  PHE D CD2 1 
ATOM 189  C CE1 . PHE A 1 32  ? 109.637 145.142 71.671  1.00 143.17 ? 32  PHE D CE1 1 
ATOM 190  C CE2 . PHE A 1 32  ? 110.987 145.300 69.712  1.00 143.17 ? 32  PHE D CE2 1 
ATOM 191  C CZ  . PHE A 1 32  ? 109.887 144.787 70.362  1.00 143.17 ? 32  PHE D CZ  1 
ATOM 192  N N   . PRO A 1 33  ? 112.839 150.752 73.777  1.00 137.31 ? 33  PRO D N   1 
ATOM 193  C CA  . PRO A 1 33  ? 113.855 151.625 74.365  1.00 137.31 ? 33  PRO D CA  1 
ATOM 194  C C   . PRO A 1 33  ? 114.669 150.906 75.429  1.00 137.31 ? 33  PRO D C   1 
ATOM 195  O O   . PRO A 1 33  ? 114.259 149.890 75.992  1.00 137.31 ? 33  PRO D O   1 
ATOM 196  C CB  . PRO A 1 33  ? 113.026 152.756 74.977  1.00 137.31 ? 33  PRO D CB  1 
ATOM 197  C CG  . PRO A 1 33  ? 111.771 152.079 75.390  1.00 137.31 ? 33  PRO D CG  1 
ATOM 198  C CD  . PRO A 1 33  ? 111.500 151.044 74.322  1.00 137.31 ? 33  PRO D CD  1 
ATOM 199  N N   . ALA A 1 34  ? 115.843 151.465 75.701  1.00 133.82 ? 34  ALA D N   1 
ATOM 200  C CA  . ALA A 1 34  ? 116.698 150.924 76.742  1.00 133.82 ? 34  ALA D CA  1 
ATOM 201  C C   . ALA A 1 34  ? 115.994 150.996 78.093  1.00 133.82 ? 34  ALA D C   1 
ATOM 202  O O   . ALA A 1 34  ? 115.356 151.992 78.443  1.00 133.82 ? 34  ALA D O   1 
ATOM 203  C CB  . ALA A 1 34  ? 118.024 151.681 76.801  1.00 133.82 ? 34  ALA D CB  1 
ATOM 204  N N   . GLY A 1 35  ? 116.119 149.916 78.855  1.00 127.09 ? 35  GLY D N   1 
ATOM 205  C CA  . GLY A 1 35  ? 115.488 149.817 80.147  1.00 127.09 ? 35  GLY D CA  1 
ATOM 206  C C   . GLY A 1 35  ? 116.048 148.654 80.938  1.00 127.09 ? 35  GLY D C   1 
ATOM 207  O O   . GLY A 1 35  ? 117.169 148.197 80.695  1.00 127.09 ? 35  GLY D O   1 
ATOM 208  N N   . PRO A 1 36  ? 115.280 148.144 81.904  1.00 115.93 ? 36  PRO D N   1 
ATOM 209  C CA  . PRO A 1 36  ? 115.759 146.992 82.679  1.00 115.93 ? 36  PRO D CA  1 
ATOM 210  C C   . PRO A 1 36  ? 115.910 145.727 81.855  1.00 115.93 ? 36  PRO D C   1 
ATOM 211  O O   . PRO A 1 36  ? 116.565 144.786 82.319  1.00 115.93 ? 36  PRO D O   1 
ATOM 212  C CB  . PRO A 1 36  ? 114.685 146.828 83.760  1.00 115.93 ? 36  PRO D CB  1 
ATOM 213  C CG  . PRO A 1 36  ? 113.458 147.396 83.148  1.00 115.93 ? 36  PRO D CG  1 
ATOM 214  C CD  . PRO A 1 36  ? 113.927 148.554 82.319  1.00 115.93 ? 36  PRO D CD  1 
ATOM 215  N N   . GLN A 1 37  ? 115.339 145.672 80.653  1.00 120.16 ? 37  GLN D N   1 
ATOM 216  C CA  . GLN A 1 37  ? 115.353 144.445 79.864  1.00 120.16 ? 37  GLN D CA  1 
ATOM 217  C C   . GLN A 1 37  ? 116.632 144.312 79.041  1.00 120.16 ? 37  GLN D C   1 
ATOM 218  O O   . GLN A 1 37  ? 117.254 143.246 79.026  1.00 120.16 ? 37  GLN D O   1 
ATOM 219  C CB  . GLN A 1 37  ? 114.114 144.392 78.961  1.00 120.16 ? 37  GLN D CB  1 
ATOM 220  C CG  . GLN A 1 37  ? 114.160 145.322 77.757  1.00 120.16 ? 37  GLN D CG  1 
ATOM 221  C CD  . GLN A 1 37  ? 112.805 145.483 77.091  1.00 120.16 ? 37  GLN D CD  1 
ATOM 222  O OE1 . GLN A 1 37  ? 111.793 144.995 77.592  1.00 120.16 ? 37  GLN D OE1 1 
ATOM 223  N NE2 . GLN A 1 37  ? 112.783 146.163 75.950  1.00 120.16 ? 37  GLN D NE2 1 
ATOM 224  N N   . CYS A 1 38  ? 117.040 145.379 78.356  1.00 126.68 ? 38  CYS D N   1 
ATOM 225  C CA  . CYS A 1 38  ? 118.197 145.307 77.472  1.00 126.68 ? 38  CYS D CA  1 
ATOM 226  C C   . CYS A 1 38  ? 118.843 146.679 77.357  1.00 126.68 ? 38  CYS D C   1 
ATOM 227  O O   . CYS A 1 38  ? 118.151 147.700 77.392  1.00 126.68 ? 38  CYS D O   1 
ATOM 228  C CB  . CYS A 1 38  ? 117.794 144.794 76.088  1.00 126.68 ? 38  CYS D CB  1 
ATOM 229  S SG  . CYS A 1 38  ? 119.080 144.950 74.833  1.00 126.68 ? 38  CYS D SG  1 
ATOM 230  N N   . SER A 1 39  ? 120.170 146.691 77.211  1.00 130.19 ? 39  SER D N   1 
ATOM 231  C CA  . SER A 1 39  ? 120.908 147.950 77.214  1.00 130.19 ? 39  SER D CA  1 
ATOM 232  C C   . SER A 1 39  ? 120.654 148.755 75.945  1.00 130.19 ? 39  SER D C   1 
ATOM 233  O O   . SER A 1 39  ? 120.363 149.956 76.005  1.00 130.19 ? 39  SER D O   1 
ATOM 234  C CB  . SER A 1 39  ? 122.402 147.673 77.372  1.00 130.19 ? 39  SER D CB  1 
ATOM 235  O OG  . SER A 1 39  ? 123.171 148.756 76.881  1.00 130.19 ? 39  SER D OG  1 
ATOM 236  N N   . LYS A 1 40  ? 120.760 148.114 74.785  1.00 134.92 ? 40  LYS D N   1 
ATOM 237  C CA  . LYS A 1 40  ? 120.742 148.822 73.513  1.00 134.92 ? 40  LYS D CA  1 
ATOM 238  C C   . LYS A 1 40  ? 119.318 148.984 73.000  1.00 134.92 ? 40  LYS D C   1 
ATOM 239  O O   . LYS A 1 40  ? 118.509 148.055 73.069  1.00 134.92 ? 40  LYS D O   1 
ATOM 240  C CB  . LYS A 1 40  ? 121.599 148.095 72.488  1.00 30.00  ? 40  LYS D CB  1 
ATOM 241  N N   . VAL A 1 41  ? 119.019 150.178 72.483  1.00 143.39 ? 41  VAL D N   1 
ATOM 242  C CA  . VAL A 1 41  ? 117.726 150.411 71.856  1.00 143.39 ? 41  VAL D CA  1 
ATOM 243  C C   . VAL A 1 41  ? 117.574 149.469 70.674  1.00 143.39 ? 41  VAL D C   1 
ATOM 244  O O   . VAL A 1 41  ? 118.521 149.241 69.914  1.00 143.39 ? 41  VAL D O   1 
ATOM 245  C CB  . VAL A 1 41  ? 117.597 151.880 71.417  1.00 143.39 ? 41  VAL D CB  1 
ATOM 246  C CG1 . VAL A 1 41  ? 116.357 152.073 70.555  1.00 143.39 ? 41  VAL D CG1 1 
ATOM 247  C CG2 . VAL A 1 41  ? 117.562 152.795 72.630  1.00 143.39 ? 41  VAL D CG2 1 
ATOM 248  N N   . GLU A 1 42  ? 116.376 148.914 70.515  1.00 147.83 ? 42  GLU D N   1 
ATOM 249  C CA  . GLU A 1 42  ? 116.100 147.952 69.457  1.00 147.83 ? 42  GLU D CA  1 
ATOM 250  C C   . GLU A 1 42  ? 115.009 148.496 68.548  1.00 147.83 ? 42  GLU D C   1 
ATOM 251  O O   . GLU A 1 42  ? 114.036 149.087 69.024  1.00 147.83 ? 42  GLU D O   1 
ATOM 252  C CB  . GLU A 1 42  ? 115.700 146.605 70.040  1.00 30.00  ? 42  GLU D CB  1 
ATOM 253  N N   . VAL A 1 43  ? 115.179 148.306 67.244  1.00 158.16 ? 43  VAL D N   1 
ATOM 254  C CA  . VAL A 1 43  ? 114.173 148.663 66.251  1.00 158.16 ? 43  VAL D CA  1 
ATOM 255  C C   . VAL A 1 43  ? 113.890 147.408 65.441  1.00 158.16 ? 43  VAL D C   1 
ATOM 256  O O   . VAL A 1 43  ? 114.775 146.900 64.738  1.00 158.16 ? 43  VAL D O   1 
ATOM 257  C CB  . VAL A 1 43  ? 114.642 149.808 65.366  1.00 30.00  ? 43  VAL D CB  1 
ATOM 258  N N   . VAL A 1 44  ? 112.664 146.902 65.537  1.00 156.06 ? 44  VAL D N   1 
ATOM 259  C CA  . VAL A 1 44  ? 112.266 145.664 64.881  1.00 156.06 ? 44  VAL D CA  1 
ATOM 260  C C   . VAL A 1 44  ? 111.300 146.005 63.758  1.00 156.06 ? 44  VAL D C   1 
ATOM 261  O O   . VAL A 1 44  ? 110.284 146.674 63.983  1.00 156.06 ? 44  VAL D O   1 
ATOM 262  C CB  . VAL A 1 44  ? 111.631 144.678 65.874  1.00 156.06 ? 44  VAL D CB  1 
ATOM 263  C CG1 . VAL A 1 44  ? 111.129 143.441 65.145  1.00 156.06 ? 44  VAL D CG1 1 
ATOM 264  C CG2 . VAL A 1 44  ? 112.634 144.296 66.949  1.00 156.06 ? 44  VAL D CG2 1 
ATOM 265  N N   . ALA A 1 45  ? 111.619 145.545 62.552  1.00 164.42 ? 45  ALA D N   1 
ATOM 266  C CA  . ALA A 1 45  ? 110.771 145.735 61.383  1.00 164.42 ? 45  ALA D CA  1 
ATOM 267  C C   . ALA A 1 45  ? 110.266 144.376 60.928  1.00 164.42 ? 45  ALA D C   1 
ATOM 268  O O   . ALA A 1 45  ? 111.056 143.530 60.496  1.00 164.42 ? 45  ALA D O   1 
ATOM 269  C CB  . ALA A 1 45  ? 111.533 146.435 60.257  1.00 164.42 ? 45  ALA D CB  1 
ATOM 270  N N   . SER A 1 46  ? 108.958 144.165 61.038  1.00 164.42 ? 46  SER D N   1 
ATOM 271  C CA  . SER A 1 46  ? 108.321 142.949 60.554  1.00 164.42 ? 46  SER D CA  1 
ATOM 272  C C   . SER A 1 46  ? 107.869 143.178 59.118  1.00 164.42 ? 46  SER D C   1 
ATOM 273  O O   . SER A 1 46  ? 107.015 144.034 58.859  1.00 164.42 ? 46  SER D O   1 
ATOM 274  C CB  . SER A 1 46  ? 107.140 142.564 61.444  1.00 164.42 ? 46  SER D CB  1 
ATOM 275  O OG  . SER A 1 46  ? 107.502 142.611 62.813  1.00 164.42 ? 46  SER D OG  1 
ATOM 276  N N   . LEU A 1 47  ? 108.446 142.418 58.192  1.00 167.15 ? 47  LEU D N   1 
ATOM 277  C CA  . LEU A 1 47  ? 108.201 142.615 56.774  1.00 167.15 ? 47  LEU D CA  1 
ATOM 278  C C   . LEU A 1 47  ? 106.867 141.999 56.363  1.00 167.15 ? 47  LEU D C   1 
ATOM 279  O O   . LEU A 1 47  ? 106.246 141.233 57.104  1.00 167.15 ? 47  LEU D O   1 
ATOM 280  C CB  . LEU A 1 47  ? 109.337 142.028 55.950  1.00 30.00  ? 47  LEU D CB  1 
ATOM 281  N N   . LYS A 1 48  ? 106.432 142.349 55.152  1.00 168.76 ? 48  LYS D N   1 
ATOM 282  C CA  . LYS A 1 48  ? 105.150 141.888 54.635  1.00 168.76 ? 48  LYS D CA  1 
ATOM 283  C C   . LYS A 1 48  ? 105.132 140.394 54.334  1.00 168.76 ? 48  LYS D C   1 
ATOM 284  O O   . LYS A 1 48  ? 104.045 139.823 54.202  1.00 168.76 ? 48  LYS D O   1 
ATOM 285  C CB  . LYS A 1 48  ? 104.782 142.674 53.386  1.00 30.00  ? 48  LYS D CB  1 
ATOM 286  N N   . ASN A 1 49  ? 106.293 139.753 54.223  1.00 170.51 ? 49  ASN D N   1 
ATOM 287  C CA  . ASN A 1 49  ? 106.372 138.326 53.943  1.00 170.51 ? 49  ASN D CA  1 
ATOM 288  C C   . ASN A 1 49  ? 106.459 137.482 55.210  1.00 170.51 ? 49  ASN D C   1 
ATOM 289  O O   . ASN A 1 49  ? 106.630 136.262 55.115  1.00 170.51 ? 49  ASN D O   1 
ATOM 290  C CB  . ASN A 1 49  ? 107.563 138.038 53.041  1.00 30.00  ? 49  ASN D CB  1 
ATOM 291  N N   . GLY A 1 50  ? 106.346 138.099 56.386  1.00 169.01 ? 50  GLY D N   1 
ATOM 292  C CA  . GLY A 1 50  ? 106.451 137.394 57.644  1.00 169.01 ? 50  GLY D CA  1 
ATOM 293  C C   . GLY A 1 50  ? 107.826 137.418 58.273  1.00 169.01 ? 50  GLY D C   1 
ATOM 294  O O   . GLY A 1 50  ? 107.956 137.063 59.452  1.00 169.01 ? 50  GLY D O   1 
ATOM 295  N N   . LYS A 1 51  ? 108.853 137.820 57.531  1.00 167.27 ? 51  LYS D N   1 
ATOM 296  C CA  . LYS A 1 51  ? 110.195 137.924 58.081  1.00 167.27 ? 51  LYS D CA  1 
ATOM 297  C C   . LYS A 1 51  ? 110.340 139.205 58.892  1.00 167.27 ? 51  LYS D C   1 
ATOM 298  O O   . LYS A 1 51  ? 109.792 140.254 58.541  1.00 167.27 ? 51  LYS D O   1 
ATOM 299  C CB  . LYS A 1 51  ? 111.234 137.871 56.971  1.00 30.00  ? 51  LYS D CB  1 
ATOM 300  N N   . GLN A 1 52  ? 111.088 139.111 59.988  1.00 160.72 ? 52  GLN D N   1 
ATOM 301  C CA  . GLN A 1 52  ? 111.379 140.252 60.840  1.00 160.72 ? 52  GLN D CA  1 
ATOM 302  C C   . GLN A 1 52  ? 112.884 140.469 60.907  1.00 160.72 ? 52  GLN D C   1 
ATOM 303  O O   . GLN A 1 52  ? 113.668 139.515 60.894  1.00 160.72 ? 52  GLN D O   1 
ATOM 304  C CB  . GLN A 1 52  ? 110.819 140.057 62.255  1.00 160.72 ? 52  GLN D CB  1 
ATOM 305  C CG  . GLN A 1 52  ? 109.349 139.677 62.298  1.00 160.72 ? 52  GLN D CG  1 
ATOM 306  C CD  . GLN A 1 52  ? 108.813 139.588 63.713  1.00 160.72 ? 52  GLN D CD  1 
ATOM 307  O OE1 . GLN A 1 52  ? 108.778 140.582 64.439  1.00 160.72 ? 52  GLN D OE1 1 
ATOM 308  N NE2 . GLN A 1 52  ? 108.394 138.394 64.114  1.00 160.72 ? 52  GLN D NE2 1 
ATOM 309  N N   . VAL A 1 53  ? 113.279 141.737 60.974  1.00 161.79 ? 53  VAL D N   1 
ATOM 310  C CA  . VAL A 1 53  ? 114.683 142.122 61.009  1.00 161.79 ? 53  VAL D CA  1 
ATOM 311  C C   . VAL A 1 53  ? 114.888 143.151 62.109  1.00 161.79 ? 53  VAL D C   1 
ATOM 312  O O   . VAL A 1 53  ? 113.941 143.796 62.571  1.00 161.79 ? 53  VAL D O   1 
ATOM 313  C CB  . VAL A 1 53  ? 115.159 142.681 59.650  1.00 161.79 ? 53  VAL D CB  1 
ATOM 314  C CG1 . VAL A 1 53  ? 115.277 141.563 58.628  1.00 161.79 ? 53  VAL D CG1 1 
ATOM 315  C CG2 . VAL A 1 53  ? 114.211 143.765 59.155  1.00 161.79 ? 53  VAL D CG2 1 
ATOM 316  N N   . CYS A 1 54  ? 116.139 143.294 62.533  1.00 159.92 ? 54  CYS D N   1 
ATOM 317  C CA  . CYS A 1 54  ? 116.530 144.288 63.521  1.00 159.92 ? 54  CYS D CA  1 
ATOM 318  C C   . CYS A 1 54  ? 117.450 145.311 62.869  1.00 159.92 ? 54  CYS D C   1 
ATOM 319  O O   . CYS A 1 54  ? 118.415 144.950 62.190  1.00 159.92 ? 54  CYS D O   1 
ATOM 320  C CB  . CYS A 1 54  ? 117.230 143.627 64.709  1.00 159.92 ? 54  CYS D CB  1 
ATOM 321  S SG  . CYS A 1 54  ? 116.279 142.284 65.462  1.00 159.92 ? 54  CYS D SG  1 
ATOM 322  N N   . LEU A 1 55  ? 117.146 146.589 63.078  1.00 162.15 ? 55  LEU D N   1 
ATOM 323  C CA  . LEU A 1 55  ? 117.834 147.677 62.402  1.00 162.15 ? 55  LEU D CA  1 
ATOM 324  C C   . LEU A 1 55  ? 118.670 148.473 63.394  1.00 162.15 ? 55  LEU D C   1 
ATOM 325  O O   . LEU A 1 55  ? 118.445 148.433 64.606  1.00 162.15 ? 55  LEU D O   1 
ATOM 326  C CB  . LEU A 1 55  ? 116.835 148.601 61.695  1.00 162.15 ? 55  LEU D CB  1 
ATOM 327  C CG  . LEU A 1 55  ? 115.899 147.890 60.717  1.00 162.15 ? 55  LEU D CG  1 
ATOM 328  C CD1 . LEU A 1 55  ? 114.805 148.829 60.232  1.00 162.15 ? 55  LEU D CD1 1 
ATOM 329  C CD2 . LEU A 1 55  ? 116.682 147.321 59.544  1.00 162.15 ? 55  LEU D CD2 1 
ATOM 330  N N   . ASP A 1 56  ? 119.645 149.196 62.862  1.00 162.01 ? 56  ASP D N   1 
ATOM 331  C CA  . ASP A 1 56  ? 120.549 149.972 63.700  1.00 162.01 ? 56  ASP D CA  1 
ATOM 332  C C   . ASP A 1 56  ? 119.852 151.237 64.182  1.00 162.01 ? 56  ASP D C   1 
ATOM 333  O O   . ASP A 1 56  ? 119.488 152.082 63.354  1.00 162.01 ? 56  ASP D O   1 
ATOM 334  C CB  . ASP A 1 56  ? 121.825 150.312 62.945  1.00 30.00  ? 56  ASP D CB  1 
ATOM 335  N N   . PRO A 1 57  ? 119.655 151.423 65.491  1.00 160.19 ? 57  PRO D N   1 
ATOM 336  C CA  . PRO A 1 57  ? 119.094 152.697 65.962  1.00 160.19 ? 57  PRO D CA  1 
ATOM 337  C C   . PRO A 1 57  ? 120.002 153.881 65.695  1.00 160.19 ? 57  PRO D C   1 
ATOM 338  O O   . PRO A 1 57  ? 119.520 155.021 65.681  1.00 160.19 ? 57  PRO D O   1 
ATOM 339  C CB  . PRO A 1 57  ? 118.903 152.462 67.465  1.00 160.19 ? 57  PRO D CB  1 
ATOM 340  C CG  . PRO A 1 57  ? 119.925 151.439 67.807  1.00 160.19 ? 57  PRO D CG  1 
ATOM 341  C CD  . PRO A 1 57  ? 119.986 150.528 66.614  1.00 160.19 ? 57  PRO D CD  1 
ATOM 342  N N   . GLU A 1 58  ? 121.297 153.648 65.483  1.00 161.74 ? 58  GLU D N   1 
ATOM 343  C CA  . GLU A 1 58  ? 122.238 154.732 65.237  1.00 161.74 ? 58  GLU D CA  1 
ATOM 344  C C   . GLU A 1 58  ? 122.276 155.158 63.777  1.00 161.74 ? 58  GLU D C   1 
ATOM 345  O O   . GLU A 1 58  ? 122.884 156.188 63.464  1.00 161.74 ? 58  GLU D O   1 
ATOM 346  C CB  . GLU A 1 58  ? 123.630 154.327 65.698  1.00 30.00  ? 58  GLU D CB  1 
ATOM 347  N N   . ALA A 1 59  ? 121.645 154.400 62.881  1.00 164.42 ? 59  ALA D N   1 
ATOM 348  C CA  . ALA A 1 59  ? 121.654 154.735 61.463  1.00 164.42 ? 59  ALA D CA  1 
ATOM 349  C C   . ALA A 1 59  ? 120.988 156.090 61.256  1.00 164.42 ? 59  ALA D C   1 
ATOM 350  O O   . ALA A 1 59  ? 119.969 156.377 61.894  1.00 164.42 ? 59  ALA D O   1 
ATOM 351  C CB  . ALA A 1 59  ? 120.939 153.656 60.648  1.00 164.42 ? 59  ALA D CB  1 
ATOM 352  N N   . PRO A 1 60  ? 121.518 156.945 60.374  1.00 168.35 ? 60  PRO D N   1 
ATOM 353  C CA  . PRO A 1 60  ? 120.940 158.297 60.250  1.00 168.35 ? 60  PRO D CA  1 
ATOM 354  C C   . PRO A 1 60  ? 119.453 158.296 59.936  1.00 168.35 ? 60  PRO D C   1 
ATOM 355  O O   . PRO A 1 60  ? 118.670 158.928 60.656  1.00 168.35 ? 60  PRO D O   1 
ATOM 356  C CB  . PRO A 1 60  ? 121.769 158.924 59.117  1.00 168.35 ? 60  PRO D CB  1 
ATOM 357  C CG  . PRO A 1 60  ? 123.037 158.146 59.091  1.00 168.35 ? 60  PRO D CG  1 
ATOM 358  C CD  . PRO A 1 60  ? 122.656 156.749 59.459  1.00 168.35 ? 60  PRO D CD  1 
ATOM 359  N N   . PHE A 1 61  ? 119.038 157.598 58.877  1.00 164.00 ? 61  PHE D N   1 
ATOM 360  C CA  . PHE A 1 61  ? 117.627 157.600 58.502  1.00 164.00 ? 61  PHE D CA  1 
ATOM 361  C C   . PHE A 1 61  ? 116.772 156.984 59.601  1.00 164.00 ? 61  PHE D C   1 
ATOM 362  O O   . PHE A 1 61  ? 115.762 157.565 60.021  1.00 164.00 ? 61  PHE D O   1 
ATOM 363  C CB  . PHE A 1 61  ? 117.431 156.847 57.184  1.00 164.00 ? 61  PHE D CB  1 
ATOM 364  C CG  . PHE A 1 61  ? 118.506 157.112 56.166  1.00 164.00 ? 61  PHE D CG  1 
ATOM 365  C CD1 . PHE A 1 61  ? 118.758 158.399 55.722  1.00 164.00 ? 61  PHE D CD1 1 
ATOM 366  C CD2 . PHE A 1 61  ? 119.268 156.073 55.659  1.00 164.00 ? 61  PHE D CD2 1 
ATOM 367  C CE1 . PHE A 1 61  ? 119.748 158.644 54.789  1.00 164.00 ? 61  PHE D CE1 1 
ATOM 368  C CE2 . PHE A 1 61  ? 120.258 156.312 54.726  1.00 164.00 ? 61  PHE D CE2 1 
ATOM 369  C CZ  . PHE A 1 61  ? 120.498 157.599 54.290  1.00 164.00 ? 61  PHE D CZ  1 
ATOM 370  N N   . LEU A 1 62  ? 117.167 155.807 60.087  1.00 162.83 ? 62  LEU D N   1 
ATOM 371  C CA  . LEU A 1 62  ? 116.402 155.157 61.143  1.00 162.83 ? 62  LEU D CA  1 
ATOM 372  C C   . LEU A 1 62  ? 116.457 155.963 62.433  1.00 162.83 ? 62  LEU D C   1 
ATOM 373  O O   . LEU A 1 62  ? 115.476 156.015 63.182  1.00 162.83 ? 62  LEU D O   1 
ATOM 374  C CB  . LEU A 1 62  ? 116.913 153.743 61.376  1.00 30.00  ? 62  LEU D CB  1 
ATOM 375  N N   . LYS A 1 63  ? 117.598 156.596 62.715  1.00 164.18 ? 63  LYS D N   1 
ATOM 376  C CA  . LYS A 1 63  ? 117.697 157.430 63.909  1.00 164.18 ? 63  LYS D CA  1 
ATOM 377  C C   . LYS A 1 63  ? 116.709 158.586 63.842  1.00 164.18 ? 63  LYS D C   1 
ATOM 378  O O   . LYS A 1 63  ? 116.020 158.889 64.823  1.00 164.18 ? 63  LYS D O   1 
ATOM 379  C CB  . LYS A 1 63  ? 119.117 157.949 64.081  1.00 30.00  ? 63  LYS D CB  1 
ATOM 380  N N   . LYS A 1 64  ? 116.624 159.244 62.684  1.00 167.02 ? 64  LYS D N   1 
ATOM 381  C CA  . LYS A 1 64  ? 115.670 160.336 62.525  1.00 167.02 ? 64  LYS D CA  1 
ATOM 382  C C   . LYS A 1 64  ? 114.238 159.833 62.642  1.00 167.02 ? 64  LYS D C   1 
ATOM 383  O O   . LYS A 1 64  ? 113.392 160.485 63.264  1.00 167.02 ? 64  LYS D O   1 
ATOM 384  C CB  . LYS A 1 64  ? 115.881 161.036 61.191  1.00 30.00  ? 64  LYS D CB  1 
ATOM 385  N N   . VAL A 1 65  ? 113.946 158.673 62.050  1.00 164.37 ? 65  VAL D N   1 
ATOM 386  C CA  . VAL A 1 65  ? 112.597 158.122 62.143  1.00 164.37 ? 65  VAL D CA  1 
ATOM 387  C C   . VAL A 1 65  ? 112.234 157.851 63.598  1.00 164.37 ? 65  VAL D C   1 
ATOM 388  O O   . VAL A 1 65  ? 111.132 158.183 64.052  1.00 164.37 ? 65  VAL D O   1 
ATOM 389  C CB  . VAL A 1 65  ? 112.479 156.849 61.284  1.00 164.37 ? 65  VAL D CB  1 
ATOM 390  C CG1 . VAL A 1 65  ? 111.182 156.115 61.592  1.00 164.37 ? 65  VAL D CG1 1 
ATOM 391  C CG2 . VAL A 1 65  ? 112.556 157.200 59.806  1.00 164.37 ? 65  VAL D CG2 1 
ATOM 392  N N   . ILE A 1 66  ? 113.153 157.247 64.352  1.00 162.12 ? 66  ILE D N   1 
ATOM 393  C CA  . ILE A 1 66  ? 112.892 156.954 65.757  1.00 162.12 ? 66  ILE D CA  1 
ATOM 394  C C   . ILE A 1 66  ? 112.698 158.242 66.545  1.00 162.12 ? 66  ILE D C   1 
ATOM 395  O O   . ILE A 1 66  ? 111.773 158.355 67.358  1.00 162.12 ? 66  ILE D O   1 
ATOM 396  C CB  . ILE A 1 66  ? 114.024 156.128 66.350  1.00 30.00  ? 66  ILE D CB  1 
ATOM 397  N N   . GLN A 1 67  ? 113.562 159.234 66.318  1.00 164.48 ? 67  GLN D N   1 
ATOM 398  C CA  . GLN A 1 67  ? 113.444 160.494 67.043  1.00 164.48 ? 67  GLN D CA  1 
ATOM 399  C C   . GLN A 1 67  ? 112.109 161.167 66.754  1.00 164.48 ? 67  GLN D C   1 
ATOM 400  O O   . GLN A 1 67  ? 111.485 161.740 67.655  1.00 164.48 ? 67  GLN D O   1 
ATOM 401  C CB  . GLN A 1 67  ? 114.596 161.421 66.688  1.00 30.00  ? 67  GLN D CB  1 
ATOM 402  N N   . LYS A 1 68  ? 111.655 161.108 65.501  1.00 166.84 ? 68  LYS D N   1 
ATOM 403  C CA  . LYS A 1 68  ? 110.358 161.683 65.160  1.00 166.84 ? 68  LYS D CA  1 
ATOM 404  C C   . LYS A 1 68  ? 109.242 161.034 65.969  1.00 166.84 ? 68  LYS D C   1 
ATOM 405  O O   . LYS A 1 68  ? 108.218 161.667 66.249  1.00 166.84 ? 68  LYS D O   1 
ATOM 406  C CB  . LYS A 1 68  ? 110.089 161.540 63.670  1.00 30.00  ? 68  LYS D CB  1 
ATOM 407  N N   . ILE A 1 69  ? 109.421 159.774 66.352  1.00 158.32 ? 69  ILE D N   1 
ATOM 408  C CA  . ILE A 1 69  ? 108.432 159.065 67.152  1.00 158.32 ? 69  ILE D CA  1 
ATOM 409  C C   . ILE A 1 69  ? 108.431 159.599 68.579  1.00 158.32 ? 69  ILE D C   1 
ATOM 410  O O   . ILE A 1 69  ? 107.639 159.165 69.417  1.00 158.32 ? 69  ILE D O   1 
ATOM 411  C CB  . ILE A 1 69  ? 108.690 157.551 67.135  1.00 158.32 ? 69  ILE D CB  1 
ATOM 412  C CG1 . ILE A 1 69  ? 108.905 157.067 65.701  1.00 158.32 ? 69  ILE D CG1 1 
ATOM 413  C CG2 . ILE A 1 69  ? 107.533 156.804 67.784  1.00 158.32 ? 69  ILE D CG2 1 
ATOM 414  C CD1 . ILE A 1 69  ? 109.118 155.576 65.585  1.00 158.32 ? 69  ILE D CD1 1 
ATOM 415  N N   . LEU B 2 89  ? 122.546 135.928 54.644  1.00 162.14 ? 33  LEU R N   1 
ATOM 416  C CA  . LEU B 2 89  ? 121.323 136.693 54.425  1.00 162.14 ? 33  LEU R CA  1 
ATOM 417  C C   . LEU B 2 89  ? 120.382 136.590 55.619  1.00 162.14 ? 33  LEU R C   1 
ATOM 418  O O   . LEU B 2 89  ? 119.768 137.584 56.022  1.00 162.14 ? 33  LEU R O   1 
ATOM 419  C CB  . LEU B 2 89  ? 120.625 136.224 53.157  1.00 30.00  ? 33  LEU R CB  1 
ATOM 420  N N   . LEU B 2 90  ? 120.258 135.397 56.198  1.00 162.69 ? 34  LEU R N   1 
ATOM 421  C CA  . LEU B 2 90  ? 119.302 135.134 57.264  1.00 162.69 ? 34  LEU R CA  1 
ATOM 422  C C   . LEU B 2 90  ? 119.925 135.220 58.652  1.00 162.69 ? 34  LEU R C   1 
ATOM 423  O O   . LEU B 2 90  ? 119.284 134.828 59.632  1.00 162.69 ? 34  LEU R O   1 
ATOM 424  C CB  . LEU B 2 90  ? 118.664 133.768 57.063  1.00 30.00  ? 34  LEU R CB  1 
ATOM 425  N N   . ASP B 2 91  ? 121.156 135.724 58.759  1.00 162.14 ? 35  ASP R N   1 
ATOM 426  C CA  . ASP B 2 91  ? 121.818 135.781 60.058  1.00 162.14 ? 35  ASP R CA  1 
ATOM 427  C C   . ASP B 2 91  ? 121.041 136.648 61.040  1.00 162.14 ? 35  ASP R C   1 
ATOM 428  O O   . ASP B 2 91  ? 120.881 136.283 62.211  1.00 162.14 ? 35  ASP R O   1 
ATOM 429  C CB  . ASP B 2 91  ? 123.242 136.311 59.893  1.00 162.14 ? 35  ASP R CB  1 
ATOM 430  C CG  . ASP B 2 91  ? 123.985 136.420 61.212  1.00 162.14 ? 35  ASP R CG  1 
ATOM 431  O OD1 . ASP B 2 91  ? 123.472 135.923 62.236  1.00 162.14 ? 35  ASP R OD1 1 
ATOM 432  O OD2 . ASP B 2 91  ? 125.086 137.009 61.225  1.00 162.14 ? 35  ASP R OD2 1 
ATOM 433  N N   . ALA B 2 92  ? 120.549 137.796 60.586  1.00 159.49 ? 36  ALA R N   1 
ATOM 434  C CA  . ALA B 2 92  ? 119.906 138.779 61.449  1.00 159.49 ? 36  ALA R CA  1 
ATOM 435  C C   . ALA B 2 92  ? 118.403 138.533 61.469  1.00 159.49 ? 36  ALA R C   1 
ATOM 436  O O   . ALA B 2 92  ? 117.747 138.591 60.424  1.00 159.49 ? 36  ALA R O   1 
ATOM 437  C CB  . ALA B 2 92  ? 120.210 140.198 60.974  1.00 159.49 ? 36  ALA R CB  1 
ATOM 438  N N   . ALA B 2 93  ? 117.867 138.264 62.657  1.00 155.17 ? 37  ALA R N   1 
ATOM 439  C CA  . ALA B 2 93  ? 116.434 138.079 62.845  1.00 155.17 ? 37  ALA R CA  1 
ATOM 440  C C   . ALA B 2 93  ? 116.131 137.945 64.333  1.00 155.17 ? 37  ALA R C   1 
ATOM 441  O O   . ALA B 2 93  ? 117.004 137.531 65.107  1.00 155.17 ? 37  ALA R O   1 
ATOM 442  C CB  . ALA B 2 93  ? 115.938 136.851 62.080  1.00 155.17 ? 37  ALA R CB  1 
ATOM 443  N N   . PRO B 2 94  ? 114.923 138.284 64.776  1.00 152.21 ? 38  PRO R N   1 
ATOM 444  C CA  . PRO B 2 94  ? 114.607 138.168 66.203  1.00 152.21 ? 38  PRO R CA  1 
ATOM 445  C C   . PRO B 2 94  ? 114.666 136.729 66.687  1.00 152.21 ? 38  PRO R C   1 
ATOM 446  O O   . PRO B 2 94  ? 114.397 135.783 65.943  1.00 152.21 ? 38  PRO R O   1 
ATOM 447  C CB  . PRO B 2 94  ? 113.180 138.722 66.297  1.00 152.21 ? 38  PRO R CB  1 
ATOM 448  C CG  . PRO B 2 94  ? 113.019 139.567 65.088  1.00 152.21 ? 38  PRO R CG  1 
ATOM 449  C CD  . PRO B 2 94  ? 113.812 138.886 64.022  1.00 152.21 ? 38  PRO R CD  1 
ATOM 450  N N   . CYS B 2 95  ? 115.026 136.575 67.958  1.00 141.04 ? 39  CYS R N   1 
ATOM 451  C CA  . CYS B 2 95  ? 115.010 135.290 68.640  1.00 141.04 ? 39  CYS R CA  1 
ATOM 452  C C   . CYS B 2 95  ? 113.815 135.236 69.581  1.00 141.04 ? 39  CYS R C   1 
ATOM 453  O O   . CYS B 2 95  ? 113.615 136.140 70.399  1.00 141.04 ? 39  CYS R O   1 
ATOM 454  C CB  . CYS B 2 95  ? 116.308 135.062 69.420  1.00 141.04 ? 39  CYS R CB  1 
ATOM 455  S SG  . CYS B 2 95  ? 116.212 133.763 70.684  1.00 141.04 ? 39  CYS R SG  1 
ATOM 456  N N   . GLU B 2 96  ? 113.019 134.173 69.457  1.00 133.48 ? 40  GLU R N   1 
ATOM 457  C CA  . GLU B 2 96  ? 111.796 134.045 70.237  1.00 133.48 ? 40  GLU R CA  1 
ATOM 458  C C   . GLU B 2 96  ? 112.080 133.319 71.541  1.00 133.48 ? 40  GLU R C   1 
ATOM 459  O O   . GLU B 2 96  ? 112.576 132.183 71.507  1.00 133.48 ? 40  GLU R O   1 
ATOM 460  C CB  . GLU B 2 96  ? 110.723 133.320 69.439  1.00 30.00  ? 40  GLU R CB  1 
ATOM 461  N N   . PRO B 2 97  ? 111.797 133.911 72.702  1.00 124.71 ? 41  PRO R N   1 
ATOM 462  C CA  . PRO B 2 97  ? 111.920 133.155 73.958  1.00 124.71 ? 41  PRO R CA  1 
ATOM 463  C C   . PRO B 2 97  ? 110.845 132.081 74.027  1.00 124.71 ? 41  PRO R C   1 
ATOM 464  O O   . PRO B 2 97  ? 109.649 132.380 74.030  1.00 124.71 ? 41  PRO R O   1 
ATOM 465  C CB  . PRO B 2 97  ? 111.734 134.223 75.042  1.00 124.71 ? 41  PRO R CB  1 
ATOM 466  C CG  . PRO B 2 97  ? 110.998 135.326 74.380  1.00 124.71 ? 41  PRO R CG  1 
ATOM 467  C CD  . PRO B 2 97  ? 111.374 135.304 72.931  1.00 124.71 ? 41  PRO R CD  1 
ATOM 468  N N   . GLU B 2 98  ? 111.278 130.827 74.083  1.00 130.72 ? 42  GLU R N   1 
ATOM 469  C CA  . GLU B 2 98  ? 110.393 129.680 73.970  1.00 130.72 ? 42  GLU R CA  1 
ATOM 470  C C   . GLU B 2 98  ? 110.146 129.064 75.341  1.00 130.72 ? 42  GLU R C   1 
ATOM 471  O O   . GLU B 2 98  ? 111.004 129.113 76.228  1.00 130.72 ? 42  GLU R O   1 
ATOM 472  C CB  . GLU B 2 98  ? 110.972 128.648 73.014  1.00 30.00  ? 42  GLU R CB  1 
ATOM 473  N N   . SER B 2 99  ? 108.958 128.485 75.505  1.00 129.71 ? 43  SER R N   1 
ATOM 474  C CA  . SER B 2 99  ? 108.577 127.841 76.753  1.00 129.71 ? 43  SER R CA  1 
ATOM 475  C C   . SER B 2 99  ? 107.521 126.786 76.457  1.00 129.71 ? 43  SER R C   1 
ATOM 476  O O   . SER B 2 99  ? 106.914 126.769 75.384  1.00 129.71 ? 43  SER R O   1 
ATOM 477  C CB  . SER B 2 99  ? 108.053 128.857 77.771  1.00 129.71 ? 43  SER R CB  1 
ATOM 478  O OG  . SER B 2 99  ? 106.869 129.477 77.302  1.00 129.71 ? 43  SER R OG  1 
ATOM 479  N N   . LEU B 2 100 ? 107.310 125.898 77.427  1.00 126.94 ? 44  LEU R N   1 
ATOM 480  C CA  . LEU B 2 100 ? 106.339 124.822 77.303  1.00 126.94 ? 44  LEU R CA  1 
ATOM 481  C C   . LEU B 2 100 ? 105.532 124.702 78.589  1.00 126.94 ? 44  LEU R C   1 
ATOM 482  O O   . LEU B 2 100 ? 106.028 124.981 79.684  1.00 126.94 ? 44  LEU R O   1 
ATOM 483  C CB  . LEU B 2 100 ? 107.027 123.488 76.986  1.00 126.94 ? 44  LEU R CB  1 
ATOM 484  C CG  . LEU B 2 100 ? 107.878 123.484 75.713  1.00 126.94 ? 44  LEU R CG  1 
ATOM 485  C CD1 . LEU B 2 100 ? 108.729 122.227 75.640  1.00 126.94 ? 44  LEU R CD1 1 
ATOM 486  C CD2 . LEU B 2 100 ? 107.002 123.613 74.474  1.00 126.94 ? 44  LEU R CD2 1 
ATOM 487  N N   . GLU B 2 101 ? 104.276 124.278 78.440  1.00 123.62 ? 45  GLU R N   1 
ATOM 488  C CA  . GLU B 2 101 ? 103.368 124.181 79.580  1.00 123.62 ? 45  GLU R CA  1 
ATOM 489  C C   . GLU B 2 101 ? 103.769 123.039 80.512  1.00 123.62 ? 45  GLU R C   1 
ATOM 490  O O   . GLU B 2 101 ? 103.593 123.136 81.737  1.00 123.62 ? 45  GLU R O   1 
ATOM 491  C CB  . GLU B 2 101 ? 101.935 123.999 79.102  1.00 30.00  ? 45  GLU R CB  1 
ATOM 492  N N   . ILE B 2 102 ? 104.291 121.944 79.955  1.00 123.47 ? 46  ILE R N   1 
ATOM 493  C CA  . ILE B 2 102 ? 104.681 120.804 80.777  1.00 123.47 ? 46  ILE R CA  1 
ATOM 494  C C   . ILE B 2 102 ? 105.696 121.232 81.825  1.00 123.47 ? 46  ILE R C   1 
ATOM 495  O O   . ILE B 2 102 ? 105.642 120.792 82.980  1.00 123.47 ? 46  ILE R O   1 
ATOM 496  C CB  . ILE B 2 102 ? 105.229 119.668 79.893  1.00 123.47 ? 46  ILE R CB  1 
ATOM 497  C CG1 . ILE B 2 102 ? 104.158 119.185 78.912  1.00 123.47 ? 46  ILE R CG1 1 
ATOM 498  C CG2 . ILE B 2 102 ? 105.719 118.515 80.757  1.00 123.47 ? 46  ILE R CG2 1 
ATOM 499  C CD1 . ILE B 2 102 ? 104.716 118.435 77.721  1.00 123.47 ? 46  ILE R CD1 1 
ATOM 500  N N   . ASN B 2 103 ? 106.647 122.086 81.438  1.00 124.20 ? 47  ASN R N   1 
ATOM 501  C CA  . ASN B 2 103 ? 107.626 122.580 82.400  1.00 124.20 ? 47  ASN R CA  1 
ATOM 502  C C   . ASN B 2 103 ? 106.949 123.354 83.522  1.00 124.20 ? 47  ASN R C   1 
ATOM 503  O O   . ASN B 2 103 ? 107.302 123.195 84.695  1.00 124.20 ? 47  ASN R O   1 
ATOM 504  C CB  . ASN B 2 103 ? 108.663 123.449 81.704  1.00 30.00  ? 47  ASN R CB  1 
ATOM 505  N N   . LYS B 2 104 ? 105.976 124.200 83.183  1.00 118.07 ? 48  LYS R N   1 
ATOM 506  C CA  . LYS B 2 104 ? 105.247 124.941 84.206  1.00 118.07 ? 48  LYS R CA  1 
ATOM 507  C C   . LYS B 2 104 ? 104.593 123.989 85.202  1.00 118.07 ? 48  LYS R C   1 
ATOM 508  O O   . LYS B 2 104 ? 104.743 124.139 86.422  1.00 118.07 ? 48  LYS R O   1 
ATOM 509  C CB  . LYS B 2 104 ? 104.204 125.846 83.567  1.00 30.00  ? 48  LYS R CB  1 
ATOM 510  N N   . TYR B 2 105 ? 103.856 123.001 84.692  1.00 118.38 ? 49  TYR R N   1 
ATOM 511  C CA  . TYR B 2 105 ? 103.142 122.074 85.567  1.00 118.38 ? 49  TYR R CA  1 
ATOM 512  C C   . TYR B 2 105 ? 104.116 121.286 86.441  1.00 118.38 ? 49  TYR R C   1 
ATOM 513  O O   . TYR B 2 105 ? 103.900 121.118 87.652  1.00 118.38 ? 49  TYR R O   1 
ATOM 514  C CB  . TYR B 2 105 ? 102.277 121.129 84.747  1.00 30.00  ? 49  TYR R CB  1 
ATOM 515  N N   . PHE B 2 106 ? 105.210 120.815 85.838  1.00 114.76 ? 50  PHE R N   1 
ATOM 516  C CA  . PHE B 2 106 ? 106.223 120.070 86.575  1.00 114.76 ? 50  PHE R CA  1 
ATOM 517  C C   . PHE B 2 106 ? 106.828 120.916 87.688  1.00 114.76 ? 50  PHE R C   1 
ATOM 518  O O   . PHE B 2 106 ? 106.990 120.445 88.822  1.00 114.76 ? 50  PHE R O   1 
ATOM 519  C CB  . PHE B 2 106 ? 107.300 119.604 85.594  1.00 114.76 ? 50  PHE R CB  1 
ATOM 520  C CG  . PHE B 2 106 ? 108.457 118.905 86.236  1.00 114.76 ? 50  PHE R CG  1 
ATOM 521  C CD1 . PHE B 2 106 ? 108.300 117.657 86.811  1.00 114.76 ? 50  PHE R CD1 1 
ATOM 522  C CD2 . PHE B 2 106 ? 109.712 119.491 86.245  1.00 114.76 ? 50  PHE R CD2 1 
ATOM 523  C CE1 . PHE B 2 106 ? 109.371 117.010 87.395  1.00 114.76 ? 50  PHE R CE1 1 
ATOM 524  C CE2 . PHE B 2 106 ? 110.786 118.851 86.826  1.00 114.76 ? 50  PHE R CE2 1 
ATOM 525  C CZ  . PHE B 2 106 ? 110.617 117.608 87.403  1.00 114.76 ? 50  PHE R CZ  1 
ATOM 526  N N   . VAL B 2 107 ? 107.158 122.172 87.385  1.00 109.80 ? 51  VAL R N   1 
ATOM 527  C CA  . VAL B 2 107 ? 107.735 123.055 88.390  1.00 109.80 ? 51  VAL R CA  1 
ATOM 528  C C   . VAL B 2 107 ? 106.753 123.272 89.528  1.00 109.80 ? 51  VAL R C   1 
ATOM 529  O O   . VAL B 2 107 ? 107.132 123.259 90.704  1.00 109.80 ? 51  VAL R O   1 
ATOM 530  C CB  . VAL B 2 107 ? 108.156 124.388 87.745  1.00 109.80 ? 51  VAL R CB  1 
ATOM 531  C CG1 . VAL B 2 107 ? 108.488 125.414 88.814  1.00 109.80 ? 51  VAL R CG1 1 
ATOM 532  C CG2 . VAL B 2 107 ? 109.342 124.176 86.827  1.00 109.80 ? 51  VAL R CG2 1 
ATOM 533  N N   . VAL B 2 108 ? 105.478 123.484 89.201  1.00 108.50 ? 52  VAL R N   1 
ATOM 534  C CA  . VAL B 2 108 ? 104.477 123.689 90.243  1.00 108.50 ? 52  VAL R CA  1 
ATOM 535  C C   . VAL B 2 108 ? 104.445 122.493 91.185  1.00 108.50 ? 52  VAL R C   1 
ATOM 536  O O   . VAL B 2 108 ? 104.499 122.640 92.416  1.00 108.50 ? 52  VAL R O   1 
ATOM 537  C CB  . VAL B 2 108 ? 103.097 123.940 89.613  1.00 108.50 ? 52  VAL R CB  1 
ATOM 538  C CG1 . VAL B 2 108 ? 102.008 123.862 90.670  1.00 108.50 ? 52  VAL R CG1 1 
ATOM 539  C CG2 . VAL B 2 108 ? 103.076 125.281 88.927  1.00 108.50 ? 52  VAL R CG2 1 
ATOM 540  N N   . ILE B 2 109 ? 104.354 121.288 90.620  1.00 107.96 ? 53  ILE R N   1 
ATOM 541  C CA  . ILE B 2 109 ? 104.232 120.099 91.459  1.00 107.96 ? 53  ILE R CA  1 
ATOM 542  C C   . ILE B 2 109 ? 105.472 119.933 92.330  1.00 107.96 ? 53  ILE R C   1 
ATOM 543  O O   . ILE B 2 109 ? 105.377 119.671 93.539  1.00 107.96 ? 53  ILE R O   1 
ATOM 544  C CB  . ILE B 2 109 ? 103.984 118.850 90.597  1.00 107.96 ? 53  ILE R CB  1 
ATOM 545  C CG1 . ILE B 2 109 ? 102.758 119.045 89.705  1.00 107.96 ? 53  ILE R CG1 1 
ATOM 546  C CG2 . ILE B 2 109 ? 103.787 117.629 91.480  1.00 107.96 ? 53  ILE R CG2 1 
ATOM 547  C CD1 . ILE B 2 109 ? 102.930 118.488 88.319  1.00 107.96 ? 53  ILE R CD1 1 
ATOM 548  N N   . ILE B 2 110 ? 106.656 120.076 91.730  1.00 104.83 ? 54  ILE R N   1 
ATOM 549  C CA  . ILE B 2 110 ? 107.887 119.877 92.487  1.00 104.83 ? 54  ILE R CA  1 
ATOM 550  C C   . ILE B 2 110 ? 107.982 120.892 93.616  1.00 104.83 ? 54  ILE R C   1 
ATOM 551  O O   . ILE B 2 110 ? 108.351 120.552 94.748  1.00 104.83 ? 54  ILE R O   1 
ATOM 552  C CB  . ILE B 2 110 ? 109.109 119.952 91.552  1.00 104.83 ? 54  ILE R CB  1 
ATOM 553  C CG1 . ILE B 2 110 ? 109.037 118.859 90.481  1.00 104.83 ? 54  ILE R CG1 1 
ATOM 554  C CG2 . ILE B 2 110 ? 110.397 119.828 92.347  1.00 104.83 ? 54  ILE R CG2 1 
ATOM 555  C CD1 . ILE B 2 110 ? 109.308 117.459 91.000  1.00 104.83 ? 54  ILE R CD1 1 
ATOM 556  N N   . TYR B 2 111 ? 107.659 122.154 93.329  1.00 102.95 ? 55  TYR R N   1 
ATOM 557  C CA  . TYR B 2 111 ? 107.741 123.178 94.360  1.00 102.95 ? 55  TYR R CA  1 
ATOM 558  C C   . TYR B 2 111 ? 106.791 122.878 95.507  1.00 102.95 ? 55  TYR R C   1 
ATOM 559  O O   . TYR B 2 111 ? 107.160 123.018 96.677  1.00 102.95 ? 55  TYR R O   1 
ATOM 560  C CB  . TYR B 2 111 ? 107.439 124.551 93.764  1.00 102.95 ? 55  TYR R CB  1 
ATOM 561  C CG  . TYR B 2 111 ? 108.671 125.310 93.341  1.00 102.95 ? 55  TYR R CG  1 
ATOM 562  C CD1 . TYR B 2 111 ? 109.399 124.922 92.228  1.00 102.95 ? 55  TYR R CD1 1 
ATOM 563  C CD2 . TYR B 2 111 ? 109.112 126.408 94.061  1.00 102.95 ? 55  TYR R CD2 1 
ATOM 564  C CE1 . TYR B 2 111 ? 110.526 125.613 91.838  1.00 102.95 ? 55  TYR R CE1 1 
ATOM 565  C CE2 . TYR B 2 111 ? 110.238 127.103 93.681  1.00 102.95 ? 55  TYR R CE2 1 
ATOM 566  C CZ  . TYR B 2 111 ? 110.942 126.702 92.569  1.00 102.95 ? 55  TYR R CZ  1 
ATOM 567  O OH  . TYR B 2 111 ? 112.066 127.394 92.186  1.00 102.95 ? 55  TYR R OH  1 
ATOM 568  N N   . ALA B 2 112 ? 105.560 122.467 95.199  1.00 105.69 ? 56  ALA R N   1 
ATOM 569  C CA  . ALA B 2 112 ? 104.631 122.155 96.280  1.00 105.69 ? 56  ALA R CA  1 
ATOM 570  C C   . ALA B 2 112 ? 105.135 120.994 97.130  1.00 105.69 ? 56  ALA R C   1 
ATOM 571  O O   . ALA B 2 112 ? 105.074 121.052 98.370  1.00 105.69 ? 56  ALA R O   1 
ATOM 572  C CB  . ALA B 2 112 ? 103.251 121.836 95.708  1.00 105.69 ? 56  ALA R CB  1 
ATOM 573  N N   . LEU B 2 113 ? 105.637 119.938 96.487  1.00 103.03 ? 57  LEU R N   1 
ATOM 574  C CA  . LEU B 2 113 ? 106.119 118.787 97.243  1.00 103.03 ? 57  LEU R CA  1 
ATOM 575  C C   . LEU B 2 113 ? 107.283 119.179 98.145  1.00 103.03 ? 57  LEU R C   1 
ATOM 576  O O   . LEU B 2 113 ? 107.340 118.777 99.317  1.00 103.03 ? 57  LEU R O   1 
ATOM 577  C CB  . LEU B 2 113 ? 106.528 117.664 96.301  1.00 30.00  ? 57  LEU R CB  1 
ATOM 578  N N   . VAL B 2 114 ? 108.219 119.970 97.617  1.00 101.60 ? 58  VAL R N   1 
ATOM 579  C CA  . VAL B 2 114 ? 109.347 120.416 98.424  1.00 101.60 ? 58  VAL R CA  1 
ATOM 580  C C   . VAL B 2 114 ? 108.869 121.287 99.574  1.00 101.60 ? 58  VAL R C   1 
ATOM 581  O O   . VAL B 2 114 ? 109.393 121.194 100.689 1.00 101.60 ? 58  VAL R O   1 
ATOM 582  C CB  . VAL B 2 114 ? 110.371 121.156 97.546  1.00 101.60 ? 58  VAL R CB  1 
ATOM 583  C CG1 . VAL B 2 114 ? 111.251 122.049 98.397  1.00 101.60 ? 58  VAL R CG1 1 
ATOM 584  C CG2 . VAL B 2 114 ? 111.211 120.162 96.768  1.00 101.60 ? 58  VAL R CG2 1 
ATOM 585  N N   . PHE B 2 115 ? 107.890 122.156 99.328  1.00 101.60 ? 59  PHE R N   1 
ATOM 586  C CA  . PHE B 2 115 ? 107.328 122.959 100.407 1.00 101.60 ? 59  PHE R CA  1 
ATOM 587  C C   . PHE B 2 115 ? 106.849 122.074 101.545 1.00 101.60 ? 59  PHE R C   1 
ATOM 588  O O   . PHE B 2 115 ? 107.212 122.283 102.710 1.00 101.60 ? 59  PHE R O   1 
ATOM 589  C CB  . PHE B 2 115 ? 106.176 123.807 99.874  1.00 101.60 ? 59  PHE R CB  1 
ATOM 590  C CG  . PHE B 2 115 ? 105.398 124.510 100.944 1.00 101.60 ? 59  PHE R CG  1 
ATOM 591  C CD1 . PHE B 2 115 ? 106.031 125.334 101.855 1.00 101.60 ? 59  PHE R CD1 1 
ATOM 592  C CD2 . PHE B 2 115 ? 104.030 124.340 101.040 1.00 101.60 ? 59  PHE R CD2 1 
ATOM 593  C CE1 . PHE B 2 115 ? 105.311 125.980 102.839 1.00 101.60 ? 59  PHE R CE1 1 
ATOM 594  C CE2 . PHE B 2 115 ? 103.306 124.982 102.020 1.00 101.60 ? 59  PHE R CE2 1 
ATOM 595  C CZ  . PHE B 2 115 ? 103.947 125.803 102.921 1.00 101.60 ? 59  PHE R CZ  1 
ATOM 596  N N   . LEU B 2 116 ? 106.034 121.071 101.221 1.00 102.67 ? 60  LEU R N   1 
ATOM 597  C CA  . LEU B 2 116 ? 105.489 120.209 102.267 1.00 102.67 ? 60  LEU R CA  1 
ATOM 598  C C   . LEU B 2 116 ? 106.602 119.485 103.018 1.00 102.67 ? 60  LEU R C   1 
ATOM 599  O O   . LEU B 2 116 ? 106.612 119.453 104.258 1.00 102.67 ? 60  LEU R O   1 
ATOM 600  C CB  . LEU B 2 116 ? 104.509 119.208 101.673 1.00 30.00  ? 60  LEU R CB  1 
ATOM 601  N N   . LEU B 2 117 ? 107.555 118.902 102.284 1.00 101.60 ? 61  LEU R N   1 
ATOM 602  C CA  . LEU B 2 117 ? 108.608 118.131 102.941 1.00 101.60 ? 61  LEU R CA  1 
ATOM 603  C C   . LEU B 2 117 ? 109.462 119.011 103.847 1.00 101.60 ? 61  LEU R C   1 
ATOM 604  O O   . LEU B 2 117 ? 109.766 118.632 104.986 1.00 101.60 ? 61  LEU R O   1 
ATOM 605  C CB  . LEU B 2 117 ? 109.481 117.437 101.898 1.00 101.60 ? 61  LEU R CB  1 
ATOM 606  C CG  . LEU B 2 117 ? 108.840 116.235 101.207 1.00 101.60 ? 61  LEU R CG  1 
ATOM 607  C CD1 . LEU B 2 117 ? 109.662 115.817 100.001 1.00 101.60 ? 61  LEU R CD1 1 
ATOM 608  C CD2 . LEU B 2 117 ? 108.688 115.079 102.179 1.00 101.60 ? 61  LEU R CD2 1 
ATOM 609  N N   . SER B 2 118 ? 109.869 120.186 103.357 1.00 101.60 ? 62  SER R N   1 
ATOM 610  C CA  . SER B 2 118 ? 110.692 121.075 104.166 1.00 101.60 ? 62  SER R CA  1 
ATOM 611  C C   . SER B 2 118 ? 109.940 121.547 105.399 1.00 101.60 ? 62  SER R C   1 
ATOM 612  O O   . SER B 2 118 ? 110.505 121.587 106.499 1.00 101.60 ? 62  SER R O   1 
ATOM 613  C CB  . SER B 2 118 ? 111.152 122.270 103.332 1.00 101.60 ? 62  SER R CB  1 
ATOM 614  O OG  . SER B 2 118 ? 112.230 121.912 102.485 1.00 101.60 ? 62  SER R OG  1 
ATOM 615  N N   . LEU B 2 119 ? 108.665 121.909 105.240 1.00 101.60 ? 63  LEU R N   1 
ATOM 616  C CA  . LEU B 2 119 ? 107.879 122.309 106.398 1.00 101.60 ? 63  LEU R CA  1 
ATOM 617  C C   . LEU B 2 119 ? 107.862 121.207 107.446 1.00 101.60 ? 63  LEU R C   1 
ATOM 618  O O   . LEU B 2 119 ? 108.140 121.457 108.626 1.00 101.60 ? 63  LEU R O   1 
ATOM 619  C CB  . LEU B 2 119 ? 106.458 122.660 105.966 1.00 101.60 ? 63  LEU R CB  1 
ATOM 620  C CG  . LEU B 2 119 ? 105.516 123.112 107.082 1.00 101.60 ? 63  LEU R CG  1 
ATOM 621  C CD1 . LEU B 2 119 ? 106.061 124.344 107.781 1.00 101.60 ? 63  LEU R CD1 1 
ATOM 622  C CD2 . LEU B 2 119 ? 104.125 123.379 106.528 1.00 101.60 ? 63  LEU R CD2 1 
ATOM 623  N N   . LEU B 2 120 ? 107.562 119.975 107.031 1.00 101.60 ? 64  LEU R N   1 
ATOM 624  C CA  . LEU B 2 120 ? 107.478 118.878 107.990 1.00 101.60 ? 64  LEU R CA  1 
ATOM 625  C C   . LEU B 2 120 ? 108.810 118.665 108.699 1.00 101.60 ? 64  LEU R C   1 
ATOM 626  O O   . LEU B 2 120 ? 108.868 118.580 109.933 1.00 101.60 ? 64  LEU R O   1 
ATOM 627  C CB  . LEU B 2 120 ? 107.035 117.597 107.282 1.00 101.60 ? 64  LEU R CB  1 
ATOM 628  C CG  . LEU B 2 120 ? 106.825 116.379 108.183 1.00 101.60 ? 64  LEU R CG  1 
ATOM 629  C CD1 . LEU B 2 120 ? 105.715 116.635 109.188 1.00 101.60 ? 64  LEU R CD1 1 
ATOM 630  C CD2 . LEU B 2 120 ? 106.520 115.147 107.348 1.00 101.60 ? 64  LEU R CD2 1 
ATOM 631  N N   . GLY B 2 121 ? 109.898 118.580 107.931 1.00 101.60 ? 65  GLY R N   1 
ATOM 632  C CA  . GLY B 2 121 ? 111.190 118.299 108.539 1.00 101.60 ? 65  GLY R CA  1 
ATOM 633  C C   . GLY B 2 121 ? 111.626 119.382 109.506 1.00 101.60 ? 65  GLY R C   1 
ATOM 634  O O   . GLY B 2 121 ? 112.065 119.097 110.626 1.00 101.60 ? 65  GLY R O   1 
ATOM 635  N N   . ASN B 2 122 ? 111.512 120.645 109.089 1.00 101.60 ? 66  ASN R N   1 
ATOM 636  C CA  . ASN B 2 122 ? 111.946 121.738 109.949 1.00 101.60 ? 66  ASN R CA  1 
ATOM 637  C C   . ASN B 2 122 ? 111.089 121.826 111.203 1.00 101.60 ? 66  ASN R C   1 
ATOM 638  O O   . ASN B 2 122 ? 111.608 122.055 112.304 1.00 101.60 ? 66  ASN R O   1 
ATOM 639  C CB  . ASN B 2 122 ? 111.908 123.049 109.171 1.00 101.60 ? 66  ASN R CB  1 
ATOM 640  C CG  . ASN B 2 122 ? 112.886 123.062 108.018 1.00 101.60 ? 66  ASN R CG  1 
ATOM 641  O OD1 . ASN B 2 122 ? 113.924 122.404 108.065 1.00 101.60 ? 66  ASN R OD1 1 
ATOM 642  N ND2 . ASN B 2 122 ? 112.555 123.802 106.968 1.00 101.60 ? 66  ASN R ND2 1 
ATOM 643  N N   . SER B 2 123 ? 109.773 121.647 111.064 1.00 101.60 ? 67  SER R N   1 
ATOM 644  C CA  . SER B 2 123 ? 108.916 121.672 112.240 1.00 101.60 ? 67  SER R CA  1 
ATOM 645  C C   . SER B 2 123 ? 109.293 120.563 113.211 1.00 101.60 ? 67  SER R C   1 
ATOM 646  O O   . SER B 2 123 ? 109.353 120.788 114.426 1.00 101.60 ? 67  SER R O   1 
ATOM 647  C CB  . SER B 2 123 ? 107.452 121.548 111.823 1.00 101.60 ? 67  SER R CB  1 
ATOM 648  O OG  . SER B 2 123 ? 107.044 122.674 111.068 1.00 101.60 ? 67  SER R OG  1 
ATOM 649  N N   . LEU B 2 124 ? 109.553 119.358 112.699 1.00 101.60 ? 68  LEU R N   1 
ATOM 650  C CA  . LEU B 2 124 ? 109.939 118.268 113.586 1.00 101.60 ? 68  LEU R CA  1 
ATOM 651  C C   . LEU B 2 124 ? 111.253 118.565 114.293 1.00 101.60 ? 68  LEU R C   1 
ATOM 652  O O   . LEU B 2 124 ? 111.384 118.300 115.493 1.00 101.60 ? 68  LEU R O   1 
ATOM 653  C CB  . LEU B 2 124 ? 110.041 116.963 112.804 1.00 101.60 ? 68  LEU R CB  1 
ATOM 654  C CG  . LEU B 2 124 ? 108.704 116.357 112.383 1.00 101.60 ? 68  LEU R CG  1 
ATOM 655  C CD1 . LEU B 2 124 ? 108.925 115.160 111.477 1.00 101.60 ? 68  LEU R CD1 1 
ATOM 656  C CD2 . LEU B 2 124 ? 107.886 115.965 113.602 1.00 101.60 ? 68  LEU R CD2 1 
ATOM 657  N N   . VAL B 2 125 ? 112.235 119.113 113.575 1.00 101.60 ? 69  VAL R N   1 
ATOM 658  C CA  . VAL B 2 125 ? 113.512 119.418 114.213 1.00 101.60 ? 69  VAL R CA  1 
ATOM 659  C C   . VAL B 2 125 ? 113.320 120.450 115.315 1.00 101.60 ? 69  VAL R C   1 
ATOM 660  O O   . VAL B 2 125 ? 113.860 120.308 116.421 1.00 101.60 ? 69  VAL R O   1 
ATOM 661  C CB  . VAL B 2 125 ? 114.537 119.894 113.168 1.00 101.60 ? 69  VAL R CB  1 
ATOM 662  C CG1 . VAL B 2 125 ? 115.636 120.711 113.826 1.00 101.60 ? 69  VAL R CG1 1 
ATOM 663  C CG2 . VAL B 2 125 ? 115.130 118.707 112.436 1.00 101.60 ? 69  VAL R CG2 1 
ATOM 664  N N   . MET B 2 126 ? 112.554 121.507 115.036 1.00 101.60 ? 70  MET R N   1 
ATOM 665  C CA  . MET B 2 126 ? 112.334 122.533 116.049 1.00 101.60 ? 70  MET R CA  1 
ATOM 666  C C   . MET B 2 126 ? 111.614 121.967 117.265 1.00 101.60 ? 70  MET R C   1 
ATOM 667  O O   . MET B 2 126 ? 111.982 122.279 118.404 1.00 101.60 ? 70  MET R O   1 
ATOM 668  C CB  . MET B 2 126 ? 111.537 123.694 115.458 1.00 101.60 ? 70  MET R CB  1 
ATOM 669  C CG  . MET B 2 126 ? 112.394 124.774 114.823 1.00 101.60 ? 70  MET R CG  1 
ATOM 670  S SD  . MET B 2 126 ? 111.672 126.414 114.999 1.00 101.60 ? 70  MET R SD  1 
ATOM 671  C CE  . MET B 2 126 ? 112.369 127.241 113.575 1.00 101.60 ? 70  MET R CE  1 
ATOM 672  N N   . LEU B 2 127 ? 110.596 121.132 117.046 1.00 101.60 ? 71  LEU R N   1 
ATOM 673  C CA  . LEU B 2 127 ? 109.875 120.537 118.165 1.00 101.60 ? 71  LEU R CA  1 
ATOM 674  C C   . LEU B 2 127 ? 110.794 119.654 118.998 1.00 101.60 ? 71  LEU R C   1 
ATOM 675  O O   . LEU B 2 127 ? 110.742 119.677 120.233 1.00 101.60 ? 71  LEU R O   1 
ATOM 676  C CB  . LEU B 2 127 ? 108.678 119.737 117.646 1.00 101.60 ? 71  LEU R CB  1 
ATOM 677  C CG  . LEU B 2 127 ? 108.131 118.628 118.549 1.00 101.60 ? 71  LEU R CG  1 
ATOM 678  C CD1 . LEU B 2 127 ? 107.621 119.199 119.861 1.00 101.60 ? 71  LEU R CD1 1 
ATOM 679  C CD2 . LEU B 2 127 ? 107.029 117.868 117.832 1.00 101.60 ? 71  LEU R CD2 1 
ATOM 680  N N   . VAL B 2 128 ? 111.642 118.861 118.342 1.00 101.60 ? 72  VAL R N   1 
ATOM 681  C CA  . VAL B 2 128 ? 112.550 117.991 119.082 1.00 101.60 ? 72  VAL R CA  1 
ATOM 682  C C   . VAL B 2 128 ? 113.517 118.820 119.916 1.00 101.60 ? 72  VAL R C   1 
ATOM 683  O O   . VAL B 2 128 ? 113.764 118.518 121.089 1.00 101.60 ? 72  VAL R O   1 
ATOM 684  C CB  . VAL B 2 128 ? 113.300 117.054 118.119 1.00 101.60 ? 72  VAL R CB  1 
ATOM 685  C CG1 . VAL B 2 128 ? 114.496 116.426 118.812 1.00 101.60 ? 72  VAL R CG1 1 
ATOM 686  C CG2 . VAL B 2 128 ? 112.365 115.982 117.597 1.00 101.60 ? 72  VAL R CG2 1 
ATOM 687  N N   . ILE B 2 129 ? 114.083 119.874 119.328 1.00 101.60 ? 73  ILE R N   1 
ATOM 688  C CA  . ILE B 2 129 ? 115.102 120.640 120.038 1.00 101.60 ? 73  ILE R CA  1 
ATOM 689  C C   . ILE B 2 129 ? 114.495 121.401 121.208 1.00 101.60 ? 73  ILE R C   1 
ATOM 690  O O   . ILE B 2 129 ? 115.025 121.371 122.324 1.00 101.60 ? 73  ILE R O   1 
ATOM 691  C CB  . ILE B 2 129 ? 115.834 121.584 119.069 1.00 101.60 ? 73  ILE R CB  1 
ATOM 692  C CG1 . ILE B 2 129 ? 116.789 120.779 118.187 1.00 101.60 ? 73  ILE R CG1 1 
ATOM 693  C CG2 . ILE B 2 129 ? 116.582 122.660 119.847 1.00 101.60 ? 73  ILE R CG2 1 
ATOM 694  C CD1 . ILE B 2 129 ? 117.578 121.609 117.203 1.00 101.60 ? 73  ILE R CD1 1 
ATOM 695  N N   . LEU B 2 130 ? 113.380 122.095 120.982 1.00 101.60 ? 74  LEU R N   1 
ATOM 696  C CA  . LEU B 2 130 ? 112.872 123.034 121.975 1.00 101.60 ? 74  LEU R CA  1 
ATOM 697  C C   . LEU B 2 130 ? 112.106 122.378 123.115 1.00 101.60 ? 74  LEU R C   1 
ATOM 698  O O   . LEU B 2 130 ? 111.911 123.020 124.153 1.00 101.60 ? 74  LEU R O   1 
ATOM 699  C CB  . LEU B 2 130 ? 111.957 124.065 121.306 1.00 101.60 ? 74  LEU R CB  1 
ATOM 700  C CG  . LEU B 2 130 ? 112.617 125.164 120.469 1.00 101.60 ? 74  LEU R CG  1 
ATOM 701  C CD1 . LEU B 2 130 ? 111.580 126.196 120.060 1.00 101.60 ? 74  LEU R CD1 1 
ATOM 702  C CD2 . LEU B 2 130 ? 113.758 125.832 121.221 1.00 101.60 ? 74  LEU R CD2 1 
ATOM 703  N N   . TYR B 2 131 ? 111.672 121.127 122.963 1.00 101.60 ? 75  TYR R N   1 
ATOM 704  C CA  . TYR B 2 131 ? 110.747 120.554 123.937 1.00 101.60 ? 75  TYR R CA  1 
ATOM 705  C C   . TYR B 2 131 ? 111.380 120.474 125.321 1.00 101.60 ? 75  TYR R C   1 
ATOM 706  O O   . TYR B 2 131 ? 110.805 120.951 126.306 1.00 101.60 ? 75  TYR R O   1 
ATOM 707  C CB  . TYR B 2 131 ? 110.289 119.173 123.474 1.00 101.60 ? 75  TYR R CB  1 
ATOM 708  C CG  . TYR B 2 131 ? 108.998 118.716 124.113 1.00 101.60 ? 75  TYR R CG  1 
ATOM 709  C CD1 . TYR B 2 131 ? 108.956 118.329 125.444 1.00 101.60 ? 75  TYR R CD1 1 
ATOM 710  C CD2 . TYR B 2 131 ? 107.819 118.675 123.383 1.00 101.60 ? 75  TYR R CD2 1 
ATOM 711  C CE1 . TYR B 2 131 ? 107.775 117.911 126.030 1.00 101.60 ? 75  TYR R CE1 1 
ATOM 712  C CE2 . TYR B 2 131 ? 106.634 118.259 123.959 1.00 101.60 ? 75  TYR R CE2 1 
ATOM 713  C CZ  . TYR B 2 131 ? 106.618 117.879 125.283 1.00 101.60 ? 75  TYR R CZ  1 
ATOM 714  O OH  . TYR B 2 131 ? 105.440 117.464 125.860 1.00 101.60 ? 75  TYR R OH  1 
ATOM 715  N N   . SER B 2 132 ? 112.565 119.877 125.418 1.00 103.67 ? 76  SER R N   1 
ATOM 716  C CA  . SER B 2 132 ? 113.254 119.689 126.688 1.00 103.67 ? 76  SER R CA  1 
ATOM 717  C C   . SER B 2 132 ? 114.612 120.371 126.629 1.00 103.67 ? 76  SER R C   1 
ATOM 718  O O   . SER B 2 132 ? 115.388 120.136 125.698 1.00 103.67 ? 76  SER R O   1 
ATOM 719  C CB  . SER B 2 132 ? 113.424 118.203 127.009 1.00 103.67 ? 76  SER R CB  1 
ATOM 720  O OG  . SER B 2 132 ? 113.749 117.463 125.847 1.00 103.67 ? 76  SER R OG  1 
ATOM 721  N N   . ARG B 2 133 ? 114.901 121.198 127.632 1.00 110.25 ? 77  ARG R N   1 
ATOM 722  C CA  . ARG B 2 133 ? 116.131 121.975 127.680 1.00 110.25 ? 77  ARG R CA  1 
ATOM 723  C C   . ARG B 2 133 ? 117.293 121.197 128.283 1.00 110.25 ? 77  ARG R C   1 
ATOM 724  O O   . ARG B 2 133 ? 118.253 121.809 128.765 1.00 110.25 ? 77  ARG R O   1 
ATOM 725  C CB  . ARG B 2 133 ? 115.903 123.270 128.463 1.00 110.25 ? 77  ARG R CB  1 
ATOM 726  C CG  . ARG B 2 133 ? 114.741 124.092 127.938 1.00 110.25 ? 77  ARG R CG  1 
ATOM 727  C CD  . ARG B 2 133 ? 114.715 125.488 128.529 1.00 110.25 ? 77  ARG R CD  1 
ATOM 728  N NE  . ARG B 2 133 ? 113.554 126.240 128.067 1.00 110.25 ? 77  ARG R NE  1 
ATOM 729  C CZ  . ARG B 2 133 ? 113.375 127.539 128.258 1.00 110.25 ? 77  ARG R CZ  1 
ATOM 730  N NH1 . ARG B 2 133 ? 114.270 128.276 128.896 1.00 110.25 ? 77  ARG R NH1 1 
ATOM 731  N NH2 . ARG B 2 133 ? 112.269 128.115 127.796 1.00 110.25 ? 77  ARG R NH2 1 
ATOM 732  N N   . VAL B 2 134 ? 117.225 119.867 128.276 1.00 110.56 ? 78  VAL R N   1 
ATOM 733  C CA  . VAL B 2 134 ? 118.332 119.058 128.767 1.00 110.56 ? 78  VAL R CA  1 
ATOM 734  C C   . VAL B 2 134 ? 119.436 119.027 127.720 1.00 110.56 ? 78  VAL R C   1 
ATOM 735  O O   . VAL B 2 134 ? 119.207 118.654 126.562 1.00 110.56 ? 78  VAL R O   1 
ATOM 736  C CB  . VAL B 2 134 ? 117.852 117.641 129.109 1.00 110.56 ? 78  VAL R CB  1 
ATOM 737  C CG1 . VAL B 2 134 ? 119.038 116.728 129.381 1.00 110.56 ? 78  VAL R CG1 1 
ATOM 738  C CG2 . VAL B 2 134 ? 116.912 117.674 130.305 1.00 110.56 ? 78  VAL R CG2 1 
ATOM 739  N N   . GLY B 2 135 ? 120.641 119.421 128.123 1.00 105.76 ? 79  GLY R N   1 
ATOM 740  C CA  . GLY B 2 135 ? 121.788 119.383 127.239 1.00 105.76 ? 79  GLY R CA  1 
ATOM 741  C C   . GLY B 2 135 ? 121.625 120.221 125.988 1.00 105.76 ? 79  GLY R C   1 
ATOM 742  O O   . GLY B 2 135 ? 121.551 119.683 124.880 1.00 105.76 ? 79  GLY R O   1 
ATOM 743  N N   . ARG B 2 136 ? 121.564 121.543 126.149 1.00 101.60 ? 80  ARG R N   1 
ATOM 744  C CA  . ARG B 2 136 ? 121.475 122.457 125.011 1.00 101.60 ? 80  ARG R CA  1 
ATOM 745  C C   . ARG B 2 136 ? 122.889 122.742 124.517 1.00 101.60 ? 80  ARG R C   1 
ATOM 746  O O   . ARG B 2 136 ? 123.476 123.797 124.767 1.00 101.60 ? 80  ARG R O   1 
ATOM 747  C CB  . ARG B 2 136 ? 120.745 123.735 125.401 1.00 101.60 ? 80  ARG R CB  1 
ATOM 748  C CG  . ARG B 2 136 ? 119.288 123.522 125.766 1.00 101.60 ? 80  ARG R CG  1 
ATOM 749  C CD  . ARG B 2 136 ? 118.445 123.200 124.544 1.00 101.60 ? 80  ARG R CD  1 
ATOM 750  N NE  . ARG B 2 136 ? 118.387 124.318 123.612 1.00 101.60 ? 80  ARG R NE  1 
ATOM 751  C CZ  . ARG B 2 136 ? 117.460 125.266 123.630 1.00 101.60 ? 80  ARG R CZ  1 
ATOM 752  N NH1 . ARG B 2 136 ? 116.493 125.273 124.534 1.00 101.60 ? 80  ARG R NH1 1 
ATOM 753  N NH2 . ARG B 2 136 ? 117.504 126.233 122.720 1.00 101.60 ? 80  ARG R NH2 1 
ATOM 754  N N   . SER B 2 137 ? 123.441 121.773 123.796 1.00 101.60 ? 81  SER R N   1 
ATOM 755  C CA  . SER B 2 137 ? 124.794 121.878 123.276 1.00 101.60 ? 81  SER R CA  1 
ATOM 756  C C   . SER B 2 137 ? 124.835 122.823 122.077 1.00 101.60 ? 81  SER R C   1 
ATOM 757  O O   . SER B 2 137 ? 123.808 123.200 121.511 1.00 101.60 ? 81  SER R O   1 
ATOM 758  C CB  . SER B 2 137 ? 125.323 120.499 122.889 1.00 101.60 ? 81  SER R CB  1 
ATOM 759  O OG  . SER B 2 137 ? 124.347 119.766 122.171 1.00 101.60 ? 81  SER R OG  1 
ATOM 760  N N   . VAL B 2 138 ? 126.053 123.202 121.690 1.00 101.60 ? 82  VAL R N   1 
ATOM 761  C CA  . VAL B 2 138 ? 126.224 124.158 120.600 1.00 101.60 ? 82  VAL R CA  1 
ATOM 762  C C   . VAL B 2 138 ? 125.560 123.646 119.328 1.00 101.60 ? 82  VAL R C   1 
ATOM 763  O O   . VAL B 2 138 ? 124.863 124.393 118.624 1.00 101.60 ? 82  VAL R O   1 
ATOM 764  C CB  . VAL B 2 138 ? 127.721 124.443 120.380 1.00 101.60 ? 82  VAL R CB  1 
ATOM 765  C CG1 . VAL B 2 138 ? 128.314 125.111 121.609 1.00 101.60 ? 82  VAL R CG1 1 
ATOM 766  C CG2 . VAL B 2 138 ? 128.474 123.163 120.046 1.00 101.60 ? 82  VAL R CG2 1 
ATOM 767  N N   . THR B 2 139 ? 125.762 122.365 119.012 1.00 101.60 ? 83  THR R N   1 
ATOM 768  C CA  . THR B 2 139 ? 125.155 121.806 117.812 1.00 101.60 ? 83  THR R CA  1 
ATOM 769  C C   . THR B 2 139 ? 123.646 121.979 117.829 1.00 101.60 ? 83  THR R C   1 
ATOM 770  O O   . THR B 2 139 ? 123.029 122.143 116.771 1.00 101.60 ? 83  THR R O   1 
ATOM 771  C CB  . THR B 2 139 ? 125.514 120.328 117.679 1.00 101.60 ? 83  THR R CB  1 
ATOM 772  O OG1 . THR B 2 139 ? 126.937 120.173 117.728 1.00 101.60 ? 83  THR R OG1 1 
ATOM 773  C CG2 . THR B 2 139 ? 124.993 119.774 116.364 1.00 101.60 ? 83  THR R CG2 1 
ATOM 774  N N   . ASP B 2 140 ? 123.035 121.956 119.012 1.00 101.60 ? 84  ASP R N   1 
ATOM 775  C CA  . ASP B 2 140 ? 121.596 122.174 119.097 1.00 101.60 ? 84  ASP R CA  1 
ATOM 776  C C   . ASP B 2 140 ? 121.233 123.578 118.627 1.00 101.60 ? 84  ASP R C   1 
ATOM 777  O O   . ASP B 2 140 ? 120.278 123.761 117.865 1.00 101.60 ? 84  ASP R O   1 
ATOM 778  C CB  . ASP B 2 140 ? 121.119 121.939 120.529 1.00 101.60 ? 84  ASP R CB  1 
ATOM 779  C CG  . ASP B 2 140 ? 121.380 120.522 121.003 1.00 101.60 ? 84  ASP R CG  1 
ATOM 780  O OD1 . ASP B 2 140 ? 121.829 119.694 120.183 1.00 101.60 ? 84  ASP R OD1 1 
ATOM 781  O OD2 . ASP B 2 140 ? 121.141 120.236 122.195 1.00 101.60 ? 84  ASP R OD2 1 
ATOM 782  N N   . VAL B 2 141 ? 121.994 124.583 119.064 1.00 101.60 ? 85  VAL R N   1 
ATOM 783  C CA  . VAL B 2 141 ? 121.737 125.953 118.630 1.00 101.60 ? 85  VAL R CA  1 
ATOM 784  C C   . VAL B 2 141 ? 121.897 126.066 117.121 1.00 101.60 ? 85  VAL R C   1 
ATOM 785  O O   . VAL B 2 141 ? 121.071 126.684 116.430 1.00 101.60 ? 85  VAL R O   1 
ATOM 786  C CB  . VAL B 2 141 ? 122.675 126.925 119.369 1.00 101.60 ? 85  VAL R CB  1 
ATOM 787  C CG1 . VAL B 2 141 ? 122.622 128.301 118.739 1.00 101.60 ? 85  VAL R CG1 1 
ATOM 788  C CG2 . VAL B 2 141 ? 122.312 126.995 120.837 1.00 101.60 ? 85  VAL R CG2 1 
ATOM 789  N N   . TYR B 2 142 ? 122.972 125.484 116.586 1.00 101.60 ? 86  TYR R N   1 
ATOM 790  C CA  . TYR B 2 142 ? 123.192 125.566 115.147 1.00 101.60 ? 86  TYR R CA  1 
ATOM 791  C C   . TYR B 2 142 ? 122.062 124.907 114.372 1.00 101.60 ? 86  TYR R C   1 
ATOM 792  O O   . TYR B 2 142 ? 121.591 125.464 113.374 1.00 101.60 ? 86  TYR R O   1 
ATOM 793  C CB  . TYR B 2 142 ? 124.526 124.928 114.778 1.00 101.60 ? 86  TYR R CB  1 
ATOM 794  C CG  . TYR B 2 142 ? 125.712 125.818 115.038 1.00 101.60 ? 86  TYR R CG  1 
ATOM 795  C CD1 . TYR B 2 142 ? 125.889 126.992 114.329 1.00 101.60 ? 86  TYR R CD1 1 
ATOM 796  C CD2 . TYR B 2 142 ? 126.656 125.483 115.992 1.00 101.60 ? 86  TYR R CD2 1 
ATOM 797  C CE1 . TYR B 2 142 ? 126.973 127.806 114.560 1.00 101.60 ? 86  TYR R CE1 1 
ATOM 798  C CE2 . TYR B 2 142 ? 127.743 126.290 116.231 1.00 101.60 ? 86  TYR R CE2 1 
ATOM 799  C CZ  . TYR B 2 142 ? 127.896 127.451 115.512 1.00 101.60 ? 86  TYR R CZ  1 
ATOM 800  O OH  . TYR B 2 142 ? 128.980 128.260 115.748 1.00 101.60 ? 86  TYR R OH  1 
ATOM 801  N N   . LEU B 2 143 ? 121.614 123.730 114.810 1.00 101.60 ? 87  LEU R N   1 
ATOM 802  C CA  . LEU B 2 143 ? 120.515 123.063 114.128 1.00 101.60 ? 87  LEU R CA  1 
ATOM 803  C C   . LEU B 2 143 ? 119.225 123.858 114.237 1.00 101.60 ? 87  LEU R C   1 
ATOM 804  O O   . LEU B 2 143 ? 118.452 123.905 113.277 1.00 101.60 ? 87  LEU R O   1 
ATOM 805  C CB  . LEU B 2 143 ? 120.324 121.656 114.688 1.00 101.60 ? 87  LEU R CB  1 
ATOM 806  C CG  . LEU B 2 143 ? 121.498 120.714 114.414 1.00 101.60 ? 87  LEU R CG  1 
ATOM 807  C CD1 . LEU B 2 143 ? 121.457 119.506 115.333 1.00 101.60 ? 87  LEU R CD1 1 
ATOM 808  C CD2 . LEU B 2 143 ? 121.507 120.280 112.960 1.00 101.60 ? 87  LEU R CD2 1 
ATOM 809  N N   . LEU B 2 144 ? 118.980 124.494 115.383 1.00 101.60 ? 88  LEU R N   1 
ATOM 810  C CA  . LEU B 2 144 ? 117.811 125.357 115.512 1.00 101.60 ? 88  LEU R CA  1 
ATOM 811  C C   . LEU B 2 144 ? 117.837 126.468 114.471 1.00 101.60 ? 88  LEU R C   1 
ATOM 812  O O   . LEU B 2 144 ? 116.848 126.697 113.763 1.00 101.60 ? 88  LEU R O   1 
ATOM 813  C CB  . LEU B 2 144 ? 117.758 125.949 116.918 1.00 101.60 ? 88  LEU R CB  1 
ATOM 814  C CG  . LEU B 2 144 ? 116.402 126.485 117.369 1.00 101.60 ? 88  LEU R CG  1 
ATOM 815  C CD1 . LEU B 2 144 ? 115.549 125.365 117.923 1.00 101.60 ? 88  LEU R CD1 1 
ATOM 816  C CD2 . LEU B 2 144 ? 116.590 127.582 118.400 1.00 101.60 ? 88  LEU R CD2 1 
ATOM 817  N N   . ASN B 2 145 ? 118.963 127.174 114.367 1.00 101.60 ? 89  ASN R N   1 
ATOM 818  C CA  . ASN B 2 145 ? 119.047 128.279 113.417 1.00 101.60 ? 89  ASN R CA  1 
ATOM 819  C C   . ASN B 2 145 ? 118.898 127.783 111.984 1.00 101.60 ? 89  ASN R C   1 
ATOM 820  O O   . ASN B 2 145 ? 118.204 128.401 111.165 1.00 101.60 ? 89  ASN R O   1 
ATOM 821  C CB  . ASN B 2 145 ? 120.366 129.020 113.599 1.00 101.60 ? 89  ASN R CB  1 
ATOM 822  C CG  . ASN B 2 145 ? 120.445 129.727 114.924 1.00 101.60 ? 89  ASN R CG  1 
ATOM 823  O OD1 . ASN B 2 145 ? 119.627 130.591 115.226 1.00 101.60 ? 89  ASN R OD1 1 
ATOM 824  N ND2 . ASN B 2 145 ? 121.420 129.353 115.735 1.00 101.60 ? 89  ASN R ND2 1 
ATOM 825  N N   . LEU B 2 146 ? 119.550 126.666 111.659 1.00 101.60 ? 90  LEU R N   1 
ATOM 826  C CA  . LEU B 2 146 ? 119.443 126.121 110.311 1.00 101.60 ? 90  LEU R CA  1 
ATOM 827  C C   . LEU B 2 146 ? 118.005 125.747 109.977 1.00 101.60 ? 90  LEU R C   1 
ATOM 828  O O   . LEU B 2 146 ? 117.526 126.033 108.870 1.00 101.60 ? 90  LEU R O   1 
ATOM 829  C CB  . LEU B 2 146 ? 120.359 124.906 110.176 1.00 101.60 ? 90  LEU R CB  1 
ATOM 830  C CG  . LEU B 2 146 ? 120.504 124.316 108.777 1.00 101.60 ? 90  LEU R CG  1 
ATOM 831  C CD1 . LEU B 2 146 ? 121.284 125.255 107.883 1.00 101.60 ? 90  LEU R CD1 1 
ATOM 832  C CD2 . LEU B 2 146 ? 121.184 122.966 108.852 1.00 101.60 ? 90  LEU R CD2 1 
ATOM 833  N N   . ALA B 2 147 ? 117.302 125.111 110.915 1.00 101.60 ? 91  ALA R N   1 
ATOM 834  C CA  . ALA B 2 147 ? 115.908 124.762 110.693 1.00 101.60 ? 91  ALA R CA  1 
ATOM 835  C C   . ALA B 2 147 ? 115.041 125.997 110.518 1.00 101.60 ? 91  ALA R C   1 
ATOM 836  O O   . ALA B 2 147 ? 114.144 125.997 109.671 1.00 101.60 ? 91  ALA R O   1 
ATOM 837  C CB  . ALA B 2 147 ? 115.385 123.917 111.853 1.00 101.60 ? 91  ALA R CB  1 
ATOM 838  N N   . LEU B 2 148 ? 115.282 127.051 111.298 1.00 101.60 ? 92  LEU R N   1 
ATOM 839  C CA  . LEU B 2 148 ? 114.520 128.281 111.103 1.00 101.60 ? 92  LEU R CA  1 
ATOM 840  C C   . LEU B 2 148 ? 114.739 128.842 109.705 1.00 101.60 ? 92  LEU R C   1 
ATOM 841  O O   . LEU B 2 148 ? 113.782 129.253 109.033 1.00 101.60 ? 92  LEU R O   1 
ATOM 842  C CB  . LEU B 2 148 ? 114.906 129.317 112.156 1.00 101.60 ? 92  LEU R CB  1 
ATOM 843  C CG  . LEU B 2 148 ? 114.290 130.705 111.983 1.00 101.60 ? 92  LEU R CG  1 
ATOM 844  C CD1 . LEU B 2 148 ? 112.784 130.642 112.106 1.00 101.60 ? 92  LEU R CD1 1 
ATOM 845  C CD2 . LEU B 2 148 ? 114.867 131.661 113.006 1.00 101.60 ? 92  LEU R CD2 1 
ATOM 846  N N   . ALA B 2 149 ? 115.993 128.873 109.252 1.00 101.60 ? 93  ALA R N   1 
ATOM 847  C CA  . ALA B 2 149 ? 116.277 129.407 107.923 1.00 101.60 ? 93  ALA R CA  1 
ATOM 848  C C   . ALA B 2 149 ? 115.567 128.596 106.846 1.00 101.60 ? 93  ALA R C   1 
ATOM 849  O O   . ALA B 2 149 ? 114.928 129.158 105.944 1.00 101.60 ? 93  ALA R O   1 
ATOM 850  C CB  . ALA B 2 149 ? 117.783 129.425 107.678 1.00 101.60 ? 93  ALA R CB  1 
ATOM 851  N N   . ASP B 2 150 ? 115.657 127.267 106.931 1.00 101.60 ? 94  ASP R N   1 
ATOM 852  C CA  . ASP B 2 150 ? 115.005 126.430 105.930 1.00 101.60 ? 94  ASP R CA  1 
ATOM 853  C C   . ASP B 2 150 ? 113.492 126.593 105.972 1.00 101.60 ? 94  ASP R C   1 
ATOM 854  O O   . ASP B 2 150 ? 112.833 126.615 104.926 1.00 101.60 ? 94  ASP R O   1 
ATOM 855  C CB  . ASP B 2 150 ? 115.395 124.969 106.132 1.00 101.60 ? 94  ASP R CB  1 
ATOM 856  C CG  . ASP B 2 150 ? 116.876 124.741 105.966 1.00 101.60 ? 94  ASP R CG  1 
ATOM 857  O OD1 . ASP B 2 150 ? 117.578 125.695 105.570 1.00 101.60 ? 94  ASP R OD1 1 
ATOM 858  O OD2 . ASP B 2 150 ? 117.340 123.611 106.221 1.00 101.60 ? 94  ASP R OD2 1 
ATOM 859  N N   . LEU B 2 151 ? 112.919 126.702 107.172 1.00 101.60 ? 95  LEU R N   1 
ATOM 860  C CA  . LEU B 2 151 ? 111.477 126.872 107.282 1.00 101.60 ? 95  LEU R CA  1 
ATOM 861  C C   . LEU B 2 151 ? 111.030 128.176 106.641 1.00 101.60 ? 95  LEU R C   1 
ATOM 862  O O   . LEU B 2 151 ? 110.011 128.214 105.945 1.00 101.60 ? 95  LEU R O   1 
ATOM 863  C CB  . LEU B 2 151 ? 111.055 126.821 108.749 1.00 101.60 ? 95  LEU R CB  1 
ATOM 864  C CG  . LEU B 2 151 ? 109.578 127.099 109.033 1.00 101.60 ? 95  LEU R CG  1 
ATOM 865  C CD1 . LEU B 2 151 ? 108.684 126.262 108.141 1.00 101.60 ? 95  LEU R CD1 1 
ATOM 866  C CD2 . LEU B 2 151 ? 109.263 126.832 110.492 1.00 101.60 ? 95  LEU R CD2 1 
ATOM 867  N N   . LEU B 2 152 ? 111.776 129.260 106.862 1.00 101.60 ? 96  LEU R N   1 
ATOM 868  C CA  . LEU B 2 152 ? 111.409 130.523 106.230 1.00 101.60 ? 96  LEU R CA  1 
ATOM 869  C C   . LEU B 2 152 ? 111.519 130.430 104.712 1.00 101.60 ? 96  LEU R C   1 
ATOM 870  O O   . LEU B 2 152 ? 110.643 130.921 103.984 1.00 101.60 ? 96  LEU R O   1 
ATOM 871  C CB  . LEU B 2 152 ? 112.283 131.655 106.766 1.00 101.60 ? 96  LEU R CB  1 
ATOM 872  C CG  . LEU B 2 152 ? 112.108 132.009 108.245 1.00 101.60 ? 96  LEU R CG  1 
ATOM 873  C CD1 . LEU B 2 152 ? 112.762 133.342 108.540 1.00 101.60 ? 96  LEU R CD1 1 
ATOM 874  C CD2 . LEU B 2 152 ? 110.645 132.040 108.648 1.00 101.60 ? 96  LEU R CD2 1 
ATOM 875  N N   . PHE B 2 153 ? 112.584 129.802 104.213 1.00 101.60 ? 97  PHE R N   1 
ATOM 876  C CA  . PHE B 2 153 ? 112.714 129.644 102.767 1.00 101.60 ? 97  PHE R CA  1 
ATOM 877  C C   . PHE B 2 153 ? 111.528 128.872 102.198 1.00 101.60 ? 97  PHE R C   1 
ATOM 878  O O   . PHE B 2 153 ? 110.940 129.266 101.179 1.00 101.60 ? 97  PHE R O   1 
ATOM 879  C CB  . PHE B 2 153 ? 114.026 128.935 102.441 1.00 101.60 ? 97  PHE R CB  1 
ATOM 880  C CG  . PHE B 2 153 ? 114.327 128.863 100.977 1.00 101.60 ? 97  PHE R CG  1 
ATOM 881  C CD1 . PHE B 2 153 ? 115.116 129.824 100.374 1.00 101.60 ? 97  PHE R CD1 1 
ATOM 882  C CD2 . PHE B 2 153 ? 113.825 127.836 100.202 1.00 101.60 ? 97  PHE R CD2 1 
ATOM 883  C CE1 . PHE B 2 153 ? 115.399 129.762 99.027  1.00 101.60 ? 97  PHE R CE1 1 
ATOM 884  C CE2 . PHE B 2 153 ? 114.103 127.770 98.854  1.00 101.60 ? 97  PHE R CE2 1 
ATOM 885  C CZ  . PHE B 2 153 ? 114.892 128.735 98.267  1.00 101.60 ? 97  PHE R CZ  1 
ATOM 886  N N   . ALA B 2 154 ? 111.151 127.776 102.854 1.00 101.60 ? 98  ALA R N   1 
ATOM 887  C CA  . ALA B 2 154 ? 109.992 127.015 102.409 1.00 101.60 ? 98  ALA R CA  1 
ATOM 888  C C   . ALA B 2 154 ? 108.722 127.849 102.463 1.00 101.60 ? 98  ALA R C   1 
ATOM 889  O O   . ALA B 2 154 ? 107.887 127.759 101.559 1.00 101.60 ? 98  ALA R O   1 
ATOM 890  C CB  . ALA B 2 154 ? 109.830 125.756 103.259 1.00 101.60 ? 98  ALA R CB  1 
ATOM 891  N N   . LEU B 2 155 ? 108.561 128.662 103.506 1.00 101.60 ? 99  LEU R N   1 
ATOM 892  C CA  . LEU B 2 155 ? 107.398 129.531 103.593 1.00 101.60 ? 99  LEU R CA  1 
ATOM 893  C C   . LEU B 2 155 ? 107.329 130.499 102.424 1.00 101.60 ? 99  LEU R C   1 
ATOM 894  O O   . LEU B 2 155 ? 106.229 130.814 101.958 1.00 101.60 ? 99  LEU R O   1 
ATOM 895  C CB  . LEU B 2 155 ? 107.424 130.304 104.912 1.00 101.60 ? 99  LEU R CB  1 
ATOM 896  C CG  . LEU B 2 155 ? 106.079 130.834 105.407 1.00 101.60 ? 99  LEU R CG  1 
ATOM 897  C CD1 . LEU B 2 155 ? 105.232 129.700 105.962 1.00 101.60 ? 99  LEU R CD1 1 
ATOM 898  C CD2 . LEU B 2 155 ? 106.286 131.914 106.456 1.00 101.60 ? 99  LEU R CD2 1 
ATOM 899  N N   . THR B 2 156 ? 108.471 130.984 101.946 1.00 101.60 ? 100 THR R N   1 
ATOM 900  C CA  . THR B 2 156 ? 108.493 131.875 100.790 1.00 101.60 ? 100 THR R CA  1 
ATOM 901  C C   . THR B 2 156 ? 108.327 131.143 99.464  1.00 101.60 ? 100 THR R C   1 
ATOM 902  O O   . THR B 2 156 ? 107.973 131.777 98.466  1.00 101.60 ? 100 THR R O   1 
ATOM 903  C CB  . THR B 2 156 ? 109.795 132.683 100.747 1.00 101.60 ? 100 THR R CB  1 
ATOM 904  O OG1 . THR B 2 156 ? 110.865 131.848 100.287 1.00 101.60 ? 100 THR R OG1 1 
ATOM 905  C CG2 . THR B 2 156 ? 110.138 133.252 102.113 1.00 101.60 ? 100 THR R CG2 1 
ATOM 906  N N   . LEU B 2 157 ? 108.582 129.836 99.421  1.00 101.60 ? 101 LEU R N   1 
ATOM 907  C CA  . LEU B 2 157 ? 108.542 129.101 98.153  1.00 101.60 ? 101 LEU R CA  1 
ATOM 908  C C   . LEU B 2 157 ? 107.242 129.267 97.359  1.00 101.60 ? 101 LEU R C   1 
ATOM 909  O O   . LEU B 2 157 ? 107.295 129.495 96.141  1.00 101.60 ? 101 LEU R O   1 
ATOM 910  C CB  . LEU B 2 157 ? 108.776 127.609 98.406  1.00 101.60 ? 101 LEU R CB  1 
ATOM 911  C CG  . LEU B 2 157 ? 110.233 127.141 98.387  1.00 101.60 ? 101 LEU R CG  1 
ATOM 912  C CD1 . LEU B 2 157 ? 110.363 125.749 98.982  1.00 101.60 ? 101 LEU R CD1 1 
ATOM 913  C CD2 . LEU B 2 157 ? 110.789 127.158 96.975  1.00 101.60 ? 101 LEU R CD2 1 
ATOM 914  N N   . PRO B 2 158 ? 106.065 129.144 97.983  1.00 101.60 ? 102 PRO R N   1 
ATOM 915  C CA  . PRO B 2 158 ? 104.818 129.121 97.187  1.00 101.60 ? 102 PRO R CA  1 
ATOM 916  C C   . PRO B 2 158 ? 104.606 130.341 96.301  1.00 101.60 ? 102 PRO R C   1 
ATOM 917  O O   . PRO B 2 158 ? 104.096 130.214 95.178  1.00 101.60 ? 102 PRO R O   1 
ATOM 918  C CB  . PRO B 2 158 ? 103.733 129.007 98.266  1.00 101.60 ? 102 PRO R CB  1 
ATOM 919  C CG  . PRO B 2 158 ? 104.412 128.355 99.411  1.00 101.60 ? 102 PRO R CG  1 
ATOM 920  C CD  . PRO B 2 158 ? 105.798 128.923 99.412  1.00 101.60 ? 102 PRO R CD  1 
ATOM 921  N N   . ILE B 2 159 ? 104.961 131.531 96.783  1.00 101.97 ? 103 ILE R N   1 
ATOM 922  C CA  . ILE B 2 159 ? 104.817 132.720 95.951  1.00 101.97 ? 103 ILE R CA  1 
ATOM 923  C C   . ILE B 2 159 ? 105.720 132.611 94.732  1.00 101.97 ? 103 ILE R C   1 
ATOM 924  O O   . ILE B 2 159 ? 105.348 133.018 93.625  1.00 101.97 ? 103 ILE R O   1 
ATOM 925  C CB  . ILE B 2 159 ? 105.108 133.989 96.770  1.00 101.97 ? 103 ILE R CB  1 
ATOM 926  C CG1 . ILE B 2 159 ? 104.089 134.130 97.903  1.00 101.97 ? 103 ILE R CG1 1 
ATOM 927  C CG2 . ILE B 2 159 ? 105.061 135.216 95.877  1.00 101.97 ? 103 ILE R CG2 1 
ATOM 928  C CD1 . ILE B 2 159 ? 104.438 135.200 98.922  1.00 101.97 ? 103 ILE R CD1 1 
ATOM 929  N N   . TRP B 2 160 ? 106.920 132.056 94.912  1.00 103.79 ? 104 TRP R N   1 
ATOM 930  C CA  . TRP B 2 160 ? 107.787 131.800 93.769  1.00 103.79 ? 104 TRP R CA  1 
ATOM 931  C C   . TRP B 2 160 ? 107.152 130.806 92.809  1.00 103.79 ? 104 TRP R C   1 
ATOM 932  O O   . TRP B 2 160 ? 107.281 130.949 91.587  1.00 103.79 ? 104 TRP R O   1 
ATOM 933  C CB  . TRP B 2 160 ? 109.143 131.283 94.239  1.00 103.79 ? 104 TRP R CB  1 
ATOM 934  C CG  . TRP B 2 160 ? 110.291 131.908 93.524  1.00 103.79 ? 104 TRP R CG  1 
ATOM 935  C CD1 . TRP B 2 160 ? 111.112 131.312 92.613  1.00 103.79 ? 104 TRP R CD1 1 
ATOM 936  C CD2 . TRP B 2 160 ? 110.751 133.256 93.656  1.00 103.79 ? 104 TRP R CD2 1 
ATOM 937  N NE1 . TRP B 2 160 ? 112.056 132.205 92.171  1.00 103.79 ? 104 TRP R NE1 1 
ATOM 938  C CE2 . TRP B 2 160 ? 111.855 133.407 92.797  1.00 103.79 ? 104 TRP R CE2 1 
ATOM 939  C CE3 . TRP B 2 160 ? 110.335 134.350 94.419  1.00 103.79 ? 104 TRP R CE3 1 
ATOM 940  C CZ2 . TRP B 2 160 ? 112.548 134.606 92.679  1.00 103.79 ? 104 TRP R CZ2 1 
ATOM 941  C CZ3 . TRP B 2 160 ? 111.025 135.539 94.301  1.00 103.79 ? 104 TRP R CZ3 1 
ATOM 942  C CH2 . TRP B 2 160 ? 112.119 135.659 93.438  1.00 103.79 ? 104 TRP R CH2 1 
ATOM 943  N N   . ALA B 2 161 ? 106.473 129.789 93.340  1.00 102.80 ? 105 ALA R N   1 
ATOM 944  C CA  . ALA B 2 161 ? 105.782 128.844 92.469  1.00 102.80 ? 105 ALA R CA  1 
ATOM 945  C C   . ALA B 2 161 ? 104.730 129.552 91.625  1.00 102.80 ? 105 ALA R C   1 
ATOM 946  O O   . ALA B 2 161 ? 104.627 129.313 90.417  1.00 102.80 ? 105 ALA R O   1 
ATOM 947  C CB  . ALA B 2 161 ? 105.142 127.735 93.301  1.00 102.80 ? 105 ALA R CB  1 
ATOM 948  N N   . ALA B 2 162 ? 103.948 130.436 92.242  1.00 103.56 ? 106 ALA R N   1 
ATOM 949  C CA  . ALA B 2 162 ? 102.949 131.186 91.484  1.00 103.56 ? 106 ALA R CA  1 
ATOM 950  C C   . ALA B 2 162 ? 103.607 132.083 90.439  1.00 103.56 ? 106 ALA R C   1 
ATOM 951  O O   . ALA B 2 162 ? 103.129 132.185 89.298  1.00 103.56 ? 106 ALA R O   1 
ATOM 952  C CB  . ALA B 2 162 ? 102.085 132.014 92.431  1.00 103.56 ? 106 ALA R CB  1 
ATOM 953  N N   . SER B 2 163 ? 104.700 132.750 90.815  1.00 104.07 ? 107 SER R N   1 
ATOM 954  C CA  . SER B 2 163 ? 105.434 133.569 89.858  1.00 104.07 ? 107 SER R CA  1 
ATOM 955  C C   . SER B 2 163 ? 105.838 132.749 88.645  1.00 104.07 ? 107 SER R C   1 
ATOM 956  O O   . SER B 2 163 ? 105.652 133.177 87.501  1.00 104.07 ? 107 SER R O   1 
ATOM 957  C CB  . SER B 2 163 ? 106.668 134.172 90.528  1.00 104.07 ? 107 SER R CB  1 
ATOM 958  O OG  . SER B 2 163 ? 107.332 135.068 89.657  1.00 104.07 ? 107 SER R OG  1 
ATOM 959  N N   . LYS B 2 164 ? 106.389 131.558 88.877  1.00 105.98 ? 108 LYS R N   1 
ATOM 960  C CA  . LYS B 2 164 ? 106.717 130.674 87.765  1.00 105.98 ? 108 LYS R CA  1 
ATOM 961  C C   . LYS B 2 164 ? 105.469 130.283 86.987  1.00 105.98 ? 108 LYS R C   1 
ATOM 962  O O   . LYS B 2 164 ? 105.535 130.086 85.769  1.00 105.98 ? 108 LYS R O   1 
ATOM 963  C CB  . LYS B 2 164 ? 107.433 129.424 88.276  1.00 105.98 ? 108 LYS R CB  1 
ATOM 964  C CG  . LYS B 2 164 ? 108.658 129.705 89.133  1.00 105.98 ? 108 LYS R CG  1 
ATOM 965  C CD  . LYS B 2 164 ? 109.935 129.272 88.438  1.00 105.98 ? 108 LYS R CD  1 
ATOM 966  C CE  . LYS B 2 164 ? 111.158 129.840 89.133  1.00 105.98 ? 108 LYS R CE  1 
ATOM 967  N NZ  . LYS B 2 164 ? 112.414 129.513 88.406  1.00 105.98 ? 108 LYS R NZ  1 
ATOM 968  N N   . VAL B 2 165 ? 104.331 130.163 87.670  1.00 106.52 ? 109 VAL R N   1 
ATOM 969  C CA  . VAL B 2 165 ? 103.093 129.783 86.995  1.00 106.52 ? 109 VAL R CA  1 
ATOM 970  C C   . VAL B 2 165 ? 102.718 130.822 85.949  1.00 106.52 ? 109 VAL R C   1 
ATOM 971  O O   . VAL B 2 165 ? 102.444 130.490 84.790  1.00 106.52 ? 109 VAL R O   1 
ATOM 972  C CB  . VAL B 2 165 ? 101.957 129.593 88.016  1.00 106.52 ? 109 VAL R CB  1 
ATOM 973  C CG1 . VAL B 2 165 ? 100.598 129.833 87.365  1.00 106.52 ? 109 VAL R CG1 1 
ATOM 974  C CG2 . VAL B 2 165 ? 102.016 128.212 88.619  1.00 106.52 ? 109 VAL R CG2 1 
ATOM 975  N N   . ASN B 2 166 ? 102.692 132.096 86.342  1.00 105.94 ? 110 ASN R N   1 
ATOM 976  C CA  . ASN B 2 166 ? 102.187 133.136 85.453  1.00 105.94 ? 110 ASN R CA  1 
ATOM 977  C C   . ASN B 2 166 ? 102.985 134.432 85.474  1.00 105.94 ? 110 ASN R C   1 
ATOM 978  O O   . ASN B 2 166 ? 102.513 135.432 84.926  1.00 105.94 ? 110 ASN R O   1 
ATOM 979  C CB  . ASN B 2 166 ? 100.722 133.455 85.792  1.00 105.94 ? 110 ASN R CB  1 
ATOM 980  C CG  . ASN B 2 166 ? 100.001 134.153 84.656  1.00 105.94 ? 110 ASN R CG  1 
ATOM 981  O OD1 . ASN B 2 166 ? 100.211 133.838 83.486  1.00 105.94 ? 110 ASN R OD1 1 
ATOM 982  N ND2 . ASN B 2 166 ? 99.143  135.107 84.998  1.00 105.94 ? 110 ASN R ND2 1 
ATOM 983  N N   . GLY B 2 167 ? 104.169 134.450 86.070  1.00 107.37 ? 111 GLY R N   1 
ATOM 984  C CA  . GLY B 2 167 ? 104.914 135.680 86.233  1.00 107.37 ? 111 GLY R CA  1 
ATOM 985  C C   . GLY B 2 167 ? 104.438 136.464 87.442  1.00 107.37 ? 111 GLY R C   1 
ATOM 986  O O   . GLY B 2 167 ? 103.477 136.105 88.125  1.00 107.37 ? 111 GLY R O   1 
ATOM 987  N N   . TRP B 2 168 ? 105.130 137.570 87.707  1.00 103.11 ? 112 TRP R N   1 
ATOM 988  C CA  . TRP B 2 168 ? 104.872 138.343 88.920  1.00 103.11 ? 112 TRP R CA  1 
ATOM 989  C C   . TRP B 2 168 ? 103.689 139.272 88.689  1.00 103.11 ? 112 TRP R C   1 
ATOM 990  O O   . TRP B 2 168 ? 103.834 140.402 88.222  1.00 103.11 ? 112 TRP R O   1 
ATOM 991  C CB  . TRP B 2 168 ? 106.106 139.125 89.345  1.00 103.11 ? 112 TRP R CB  1 
ATOM 992  C CG  . TRP B 2 168 ? 106.069 139.436 90.794  1.00 103.11 ? 112 TRP R CG  1 
ATOM 993  C CD1 . TRP B 2 168 ? 105.648 140.592 91.372  1.00 103.11 ? 112 TRP R CD1 1 
ATOM 994  C CD2 . TRP B 2 168 ? 106.449 138.567 91.863  1.00 103.11 ? 112 TRP R CD2 1 
ATOM 995  N NE1 . TRP B 2 168 ? 105.744 140.501 92.738  1.00 103.11 ? 112 TRP R NE1 1 
ATOM 996  C CE2 . TRP B 2 168 ? 106.238 139.266 93.064  1.00 103.11 ? 112 TRP R CE2 1 
ATOM 997  C CE3 . TRP B 2 168 ? 106.952 137.267 91.920  1.00 103.11 ? 112 TRP R CE3 1 
ATOM 998  C CZ2 . TRP B 2 168 ? 106.507 138.708 94.307  1.00 103.11 ? 112 TRP R CZ2 1 
ATOM 999  C CZ3 . TRP B 2 168 ? 107.224 136.716 93.153  1.00 103.11 ? 112 TRP R CZ3 1 
ATOM 1000 C CH2 . TRP B 2 168 ? 107.004 137.437 94.331  1.00 103.11 ? 112 TRP R CH2 1 
ATOM 1001 N N   . ILE B 2 169 ? 102.497 138.786 89.031  1.00 102.76 ? 113 ILE R N   1 
ATOM 1002 C CA  . ILE B 2 169 ? 101.286 139.595 89.014  1.00 102.76 ? 113 ILE R CA  1 
ATOM 1003 C C   . ILE B 2 169 ? 100.894 140.041 90.418  1.00 102.76 ? 113 ILE R C   1 
ATOM 1004 O O   . ILE B 2 169 ? 99.813  140.602 90.609  1.00 102.76 ? 113 ILE R O   1 
ATOM 1005 C CB  . ILE B 2 169 ? 100.132 138.833 88.343  1.00 102.76 ? 113 ILE R CB  1 
ATOM 1006 C CG1 . ILE B 2 169 ? 100.590 138.236 87.012  1.00 102.76 ? 113 ILE R CG1 1 
ATOM 1007 C CG2 . ILE B 2 169 ? 98.938  139.749 88.111  1.00 102.76 ? 113 ILE R CG2 1 
ATOM 1008 C CD1 . ILE B 2 169 ? 101.208 139.245 86.066  1.00 102.76 ? 113 ILE R CD1 1 
ATOM 1009 N N   . PHE B 2 170 ? 101.757 139.814 91.404  1.00 103.30 ? 114 PHE R N   1 
ATOM 1010 C CA  . PHE B 2 170 ? 101.396 139.992 92.801  1.00 103.30 ? 114 PHE R CA  1 
ATOM 1011 C C   . PHE B 2 170 ? 101.744 141.369 93.353  1.00 103.30 ? 114 PHE R C   1 
ATOM 1012 O O   . PHE B 2 170 ? 101.379 141.665 94.495  1.00 103.30 ? 114 PHE R O   1 
ATOM 1013 C CB  . PHE B 2 170 ? 102.077 138.910 93.640  1.00 103.30 ? 114 PHE R CB  1 
ATOM 1014 C CG  . PHE B 2 170 ? 101.587 137.524 93.340  1.00 103.30 ? 114 PHE R CG  1 
ATOM 1015 C CD1 . PHE B 2 170 ? 101.967 136.877 92.178  1.00 103.30 ? 114 PHE R CD1 1 
ATOM 1016 C CD2 . PHE B 2 170 ? 100.741 136.871 94.216  1.00 103.30 ? 114 PHE R CD2 1 
ATOM 1017 C CE1 . PHE B 2 170 ? 101.515 135.605 91.898  1.00 103.30 ? 114 PHE R CE1 1 
ATOM 1018 C CE2 . PHE B 2 170 ? 100.287 135.598 93.941  1.00 103.30 ? 114 PHE R CE2 1 
ATOM 1019 C CZ  . PHE B 2 170 ? 100.674 134.967 92.780  1.00 103.30 ? 114 PHE R CZ  1 
ATOM 1020 N N   . GLY B 2 171 ? 102.423 142.213 92.585  1.00 104.03 ? 115 GLY R N   1 
ATOM 1021 C CA  . GLY B 2 171 ? 102.715 143.568 93.004  1.00 104.03 ? 115 GLY R CA  1 
ATOM 1022 C C   . GLY B 2 171 ? 104.183 143.775 93.336  1.00 104.03 ? 115 GLY R C   1 
ATOM 1023 O O   . GLY B 2 171 ? 104.963 142.836 93.512  1.00 104.03 ? 115 GLY R O   1 
ATOM 1024 N N   . THR B 2 172 ? 104.554 145.055 93.423  1.00 103.45 ? 116 THR R N   1 
ATOM 1025 C CA  . THR B 2 172 ? 105.948 145.413 93.665  1.00 103.45 ? 116 THR R CA  1 
ATOM 1026 C C   . THR B 2 172 ? 106.352 145.165 95.115  1.00 103.45 ? 116 THR R C   1 
ATOM 1027 O O   . THR B 2 172 ? 107.462 144.685 95.382  1.00 103.45 ? 116 THR R O   1 
ATOM 1028 C CB  . THR B 2 172 ? 106.178 146.876 93.295  1.00 103.45 ? 116 THR R CB  1 
ATOM 1029 O OG1 . THR B 2 172 ? 106.024 147.042 91.880  1.00 103.45 ? 116 THR R OG1 1 
ATOM 1030 C CG2 . THR B 2 172 ? 107.571 147.321 93.709  1.00 103.45 ? 116 THR R CG2 1 
ATOM 1031 N N   . PHE B 2 173 ? 105.476 145.498 96.065  1.00 101.60 ? 117 PHE R N   1 
ATOM 1032 C CA  . PHE B 2 173 ? 105.824 145.326 97.471  1.00 101.60 ? 117 PHE R CA  1 
ATOM 1033 C C   . PHE B 2 173 ? 106.102 143.864 97.786  1.00 101.60 ? 117 PHE R C   1 
ATOM 1034 O O   . PHE B 2 173 ? 107.058 143.538 98.500  1.00 101.60 ? 117 PHE R O   1 
ATOM 1035 C CB  . PHE B 2 173 ? 104.706 145.859 98.362  1.00 101.60 ? 117 PHE R CB  1 
ATOM 1036 C CG  . PHE B 2 173 ? 105.053 145.864 99.820  1.00 101.60 ? 117 PHE R CG  1 
ATOM 1037 C CD1 . PHE B 2 173 ? 105.952 146.785 100.327 1.00 101.60 ? 117 PHE R CD1 1 
ATOM 1038 C CD2 . PHE B 2 173 ? 104.489 144.943 100.684 1.00 101.60 ? 117 PHE R CD2 1 
ATOM 1039 C CE1 . PHE B 2 173 ? 106.276 146.792 101.669 1.00 101.60 ? 117 PHE R CE1 1 
ATOM 1040 C CE2 . PHE B 2 173 ? 104.810 144.946 102.028 1.00 101.60 ? 117 PHE R CE2 1 
ATOM 1041 C CZ  . PHE B 2 173 ? 105.704 145.872 102.520 1.00 101.60 ? 117 PHE R CZ  1 
ATOM 1042 N N   . LEU B 2 174 ? 105.266 142.964 97.267  1.00 103.27 ? 118 LEU R N   1 
ATOM 1043 C CA  . LEU B 2 174 ? 105.508 141.543 97.476  1.00 103.27 ? 118 LEU R CA  1 
ATOM 1044 C C   . LEU B 2 174 ? 106.804 141.104 96.807  1.00 103.27 ? 118 LEU R C   1 
ATOM 1045 O O   . LEU B 2 174 ? 107.555 140.306 97.373  1.00 103.27 ? 118 LEU R O   1 
ATOM 1046 C CB  . LEU B 2 174 ? 104.325 140.722 96.965  1.00 103.27 ? 118 LEU R CB  1 
ATOM 1047 C CG  . LEU B 2 174 ? 103.070 140.749 97.842  1.00 103.27 ? 118 LEU R CG  1 
ATOM 1048 C CD1 . LEU B 2 174 ? 101.968 139.899 97.235  1.00 103.27 ? 118 LEU R CD1 1 
ATOM 1049 C CD2 . LEU B 2 174 ? 103.384 140.277 99.252  1.00 103.27 ? 118 LEU R CD2 1 
ATOM 1050 N N   . CYS B 2 175 ? 107.087 141.604 95.601  1.00 104.90 ? 119 CYS R N   1 
ATOM 1051 C CA  . CYS B 2 175 ? 108.374 141.303 94.980  1.00 104.90 ? 119 CYS R CA  1 
ATOM 1052 C C   . CYS B 2 175 ? 109.520 141.656 95.916  1.00 104.90 ? 119 CYS R C   1 
ATOM 1053 O O   . CYS B 2 175 ? 110.370 140.809 96.216  1.00 104.90 ? 119 CYS R O   1 
ATOM 1054 C CB  . CYS B 2 175 ? 108.503 142.049 93.650  1.00 104.90 ? 119 CYS R CB  1 
ATOM 1055 S SG  . CYS B 2 175 ? 110.191 142.245 92.984  1.00 104.90 ? 119 CYS R SG  1 
ATOM 1056 N N   . LYS B 2 176 ? 109.533 142.887 96.426  1.00 101.60 ? 120 LYS R N   1 
ATOM 1057 C CA  . LYS B 2 176 ? 110.626 143.300 97.299  1.00 101.60 ? 120 LYS R CA  1 
ATOM 1058 C C   . LYS B 2 176 ? 110.703 142.425 98.545  1.00 101.60 ? 120 LYS R C   1 
ATOM 1059 O O   . LYS B 2 176 ? 111.777 141.915 98.886  1.00 101.60 ? 120 LYS R O   1 
ATOM 1060 C CB  . LYS B 2 176 ? 110.458 144.766 97.687  1.00 99.14  ? 120 LYS R CB  1 
ATOM 1061 C CG  . LYS B 2 176 ? 110.614 145.731 96.531  1.00 99.14  ? 120 LYS R CG  1 
ATOM 1062 C CD  . LYS B 2 176 ? 110.510 147.167 97.003  1.00 99.14  ? 120 LYS R CD  1 
ATOM 1063 C CE  . LYS B 2 176 ? 110.929 148.141 95.924  1.00 99.14  ? 120 LYS R CE  1 
ATOM 1064 N NZ  . LYS B 2 176 ? 112.383 148.046 95.634  1.00 99.14  ? 120 LYS R NZ  1 
ATOM 1065 N N   . VAL B 2 177 ? 109.575 142.224 99.226  1.00 101.72 ? 121 VAL R N   1 
ATOM 1066 C CA  . VAL B 2 177 ? 109.590 141.516 100.504 1.00 101.72 ? 121 VAL R CA  1 
ATOM 1067 C C   . VAL B 2 177 ? 110.015 140.065 100.308 1.00 101.72 ? 121 VAL R C   1 
ATOM 1068 O O   . VAL B 2 177 ? 110.885 139.549 101.022 1.00 101.72 ? 121 VAL R O   1 
ATOM 1069 C CB  . VAL B 2 177 ? 108.212 141.607 101.179 1.00 101.72 ? 121 VAL R CB  1 
ATOM 1070 C CG1 . VAL B 2 177 ? 108.060 140.525 102.239 1.00 101.72 ? 121 VAL R CG1 1 
ATOM 1071 C CG2 . VAL B 2 177 ? 108.012 142.987 101.783 1.00 101.72 ? 121 VAL R CG2 1 
ATOM 1072 N N   . VAL B 2 178 ? 109.390 139.381 99.348  1.00 103.19 ? 122 VAL R N   1 
ATOM 1073 C CA  . VAL B 2 178 ? 109.686 137.973 99.116  1.00 103.19 ? 122 VAL R CA  1 
ATOM 1074 C C   . VAL B 2 178 ? 111.132 137.799 98.682  1.00 103.19 ? 122 VAL R C   1 
ATOM 1075 O O   . VAL B 2 178 ? 111.824 136.883 99.140  1.00 103.19 ? 122 VAL R O   1 
ATOM 1076 C CB  . VAL B 2 178 ? 108.709 137.391 98.078  1.00 103.19 ? 122 VAL R CB  1 
ATOM 1077 C CG1 . VAL B 2 178 ? 109.214 136.060 97.553  1.00 103.19 ? 122 VAL R CG1 1 
ATOM 1078 C CG2 . VAL B 2 178 ? 107.329 137.234 98.690  1.00 103.19 ? 122 VAL R CG2 1 
ATOM 1079 N N   . SER B 2 179 ? 111.616 138.663 97.785  1.00 101.60 ? 123 SER R N   1 
ATOM 1080 C CA  . SER B 2 179 ? 112.998 138.543 97.342  1.00 101.60 ? 123 SER R CA  1 
ATOM 1081 C C   . SER B 2 179 ? 113.965 138.754 98.499  1.00 101.60 ? 123 SER R C   1 
ATOM 1082 O O   . SER B 2 179 ? 114.944 138.011 98.644  1.00 101.60 ? 123 SER R O   1 
ATOM 1083 C CB  . SER B 2 179 ? 113.270 139.541 96.220  1.00 101.60 ? 123 SER R CB  1 
ATOM 1084 O OG  . SER B 2 179 ? 112.327 139.393 95.174  1.00 101.60 ? 123 SER R OG  1 
ATOM 1085 N N   . LEU B 2 180 ? 113.705 139.758 99.341  1.00 101.60 ? 124 LEU R N   1 
ATOM 1086 C CA  . LEU B 2 180 ? 114.561 139.984 100.500 1.00 101.60 ? 124 LEU R CA  1 
ATOM 1087 C C   . LEU B 2 180 ? 114.596 138.756 101.395 1.00 101.60 ? 124 LEU R C   1 
ATOM 1088 O O   . LEU B 2 180 ? 115.671 138.285 101.785 1.00 101.60 ? 124 LEU R O   1 
ATOM 1089 C CB  . LEU B 2 180 ? 114.070 141.198 101.287 1.00 101.60 ? 124 LEU R CB  1 
ATOM 1090 C CG  . LEU B 2 180 ? 114.704 141.380 102.669 1.00 101.60 ? 124 LEU R CG  1 
ATOM 1091 C CD1 . LEU B 2 180 ? 116.204 141.558 102.543 1.00 101.60 ? 124 LEU R CD1 1 
ATOM 1092 C CD2 . LEU B 2 180 ? 114.086 142.558 103.396 1.00 101.60 ? 124 LEU R CD2 1 
ATOM 1093 N N   . LEU B 2 181 ? 113.421 138.232 101.745 1.00 101.60 ? 125 LEU R N   1 
ATOM 1094 C CA  . LEU B 2 181 ? 113.374 137.091 102.651 1.00 101.60 ? 125 LEU R CA  1 
ATOM 1095 C C   . LEU B 2 181 ? 114.082 135.886 102.048 1.00 101.60 ? 125 LEU R C   1 
ATOM 1096 O O   . LEU B 2 181 ? 114.855 135.201 102.731 1.00 101.60 ? 125 LEU R O   1 
ATOM 1097 C CB  . LEU B 2 181 ? 111.923 136.757 102.989 1.00 101.60 ? 125 LEU R CB  1 
ATOM 1098 C CG  . LEU B 2 181 ? 111.694 135.731 104.097 1.00 101.60 ? 125 LEU R CG  1 
ATOM 1099 C CD1 . LEU B 2 181 ? 112.458 136.111 105.351 1.00 101.60 ? 125 LEU R CD1 1 
ATOM 1100 C CD2 . LEU B 2 181 ? 110.211 135.611 104.400 1.00 101.60 ? 125 LEU R CD2 1 
ATOM 1101 N N   . LYS B 2 182 ? 113.849 135.623 100.760 1.00 101.60 ? 126 LYS R N   1 
ATOM 1102 C CA  . LYS B 2 182 ? 114.478 134.484 100.103 1.00 101.60 ? 126 LYS R CA  1 
ATOM 1103 C C   . LYS B 2 182 ? 115.994 134.611 100.115 1.00 101.60 ? 126 LYS R C   1 
ATOM 1104 O O   . LYS B 2 182 ? 116.705 133.669 100.487 1.00 101.60 ? 126 LYS R O   1 
ATOM 1105 C CB  . LYS B 2 182 ? 113.964 134.367 98.669  1.00 101.60 ? 126 LYS R CB  1 
ATOM 1106 C CG  . LYS B 2 182 ? 114.503 133.168 97.916  1.00 101.60 ? 126 LYS R CG  1 
ATOM 1107 C CD  . LYS B 2 182 ? 113.699 132.898 96.661  1.00 101.60 ? 126 LYS R CD  1 
ATOM 1108 C CE  . LYS B 2 182 ? 113.950 131.499 96.137  1.00 101.60 ? 126 LYS R CE  1 
ATOM 1109 N NZ  . LYS B 2 182 ? 113.164 131.222 94.907  1.00 101.60 ? 126 LYS R NZ  1 
ATOM 1110 N N   . GLU B 2 183 ? 116.513 135.768 99.701  1.00 101.60 ? 127 GLU R N   1 
ATOM 1111 C CA  . GLU B 2 183 ? 117.959 135.923 99.642  1.00 101.60 ? 127 GLU R CA  1 
ATOM 1112 C C   . GLU B 2 183 ? 118.582 135.851 101.028 1.00 101.60 ? 127 GLU R C   1 
ATOM 1113 O O   . GLU B 2 183 ? 119.645 135.238 101.199 1.00 101.60 ? 127 GLU R O   1 
ATOM 1114 C CB  . GLU B 2 183 ? 118.321 137.239 98.958  1.00 101.60 ? 127 GLU R CB  1 
ATOM 1115 C CG  . GLU B 2 183 ? 119.487 137.114 97.990  1.00 101.60 ? 127 GLU R CG  1 
ATOM 1116 C CD  . GLU B 2 183 ? 120.062 138.455 97.578  1.00 101.60 ? 127 GLU R CD  1 
ATOM 1117 O OE1 . GLU B 2 183 ? 119.674 139.482 98.173  1.00 101.60 ? 127 GLU R OE1 1 
ATOM 1118 O OE2 . GLU B 2 183 ? 120.903 138.483 96.655  1.00 101.60 ? 127 GLU R OE2 1 
ATOM 1119 N N   . VAL B 2 184 ? 117.938 136.456 102.030 1.00 101.60 ? 128 VAL R N   1 
ATOM 1120 C CA  . VAL B 2 184 ? 118.476 136.394 103.383 1.00 101.60 ? 128 VAL R CA  1 
ATOM 1121 C C   . VAL B 2 184 ? 118.526 134.954 103.866 1.00 101.60 ? 128 VAL R C   1 
ATOM 1122 O O   . VAL B 2 184 ? 119.528 134.514 104.442 1.00 101.60 ? 128 VAL R O   1 
ATOM 1123 C CB  . VAL B 2 184 ? 117.647 137.277 104.332 1.00 101.60 ? 128 VAL R CB  1 
ATOM 1124 C CG1 . VAL B 2 184 ? 117.933 136.914 105.779 1.00 101.60 ? 128 VAL R CG1 1 
ATOM 1125 C CG2 . VAL B 2 184 ? 117.944 138.742 104.086 1.00 101.60 ? 128 VAL R CG2 1 
ATOM 1126 N N   . ASN B 2 185 ? 117.452 134.194 103.645 1.00 101.60 ? 129 ASN R N   1 
ATOM 1127 C CA  . ASN B 2 185 ? 117.443 132.807 104.090 1.00 101.60 ? 129 ASN R CA  1 
ATOM 1128 C C   . ASN B 2 185 ? 118.512 131.994 103.377 1.00 101.60 ? 129 ASN R C   1 
ATOM 1129 O O   . ASN B 2 185 ? 119.181 131.162 103.996 1.00 101.60 ? 129 ASN R O   1 
ATOM 1130 C CB  . ASN B 2 185 ? 116.065 132.198 103.866 1.00 101.60 ? 129 ASN R CB  1 
ATOM 1131 C CG  . ASN B 2 185 ? 114.986 132.931 104.624 1.00 101.60 ? 129 ASN R CG  1 
ATOM 1132 O OD1 . ASN B 2 185 ? 115.261 133.609 105.614 1.00 101.60 ? 129 ASN R OD1 1 
ATOM 1133 N ND2 . ASN B 2 185 ? 113.748 132.802 104.163 1.00 101.60 ? 129 ASN R ND2 1 
ATOM 1134 N N   . PHE B 2 186 ? 118.688 132.216 102.076 1.00 101.60 ? 130 PHE R N   1 
ATOM 1135 C CA  . PHE B 2 186 ? 119.697 131.472 101.329 1.00 101.60 ? 130 PHE R CA  1 
ATOM 1136 C C   . PHE B 2 186 ? 121.096 131.753 101.871 1.00 101.60 ? 130 PHE R C   1 
ATOM 1137 O O   . PHE B 2 186 ? 121.865 130.822 102.167 1.00 101.60 ? 130 PHE R O   1 
ATOM 1138 C CB  . PHE B 2 186 ? 119.580 131.832 99.847  1.00 101.60 ? 130 PHE R CB  1 
ATOM 1139 C CG  . PHE B 2 186 ? 120.820 131.587 99.052  1.00 101.60 ? 130 PHE R CG  1 
ATOM 1140 C CD1 . PHE B 2 186 ? 121.440 130.356 99.064  1.00 101.60 ? 130 PHE R CD1 1 
ATOM 1141 C CD2 . PHE B 2 186 ? 121.351 132.591 98.265  1.00 101.60 ? 130 PHE R CD2 1 
ATOM 1142 C CE1 . PHE B 2 186 ? 122.577 130.137 98.320  1.00 101.60 ? 130 PHE R CE1 1 
ATOM 1143 C CE2 . PHE B 2 186 ? 122.485 132.378 97.518  1.00 101.60 ? 130 PHE R CE2 1 
ATOM 1144 C CZ  . PHE B 2 186 ? 123.100 131.151 97.545  1.00 101.60 ? 130 PHE R CZ  1 
ATOM 1145 N N   . TYR B 2 187 ? 121.434 133.034 102.039 1.00 101.60 ? 131 TYR R N   1 
ATOM 1146 C CA  . TYR B 2 187 ? 122.749 133.375 102.569 1.00 101.60 ? 131 TYR R CA  1 
ATOM 1147 C C   . TYR B 2 187 ? 122.950 132.819 103.972 1.00 101.60 ? 131 TYR R C   1 
ATOM 1148 O O   . TYR B 2 187 ? 124.025 132.284 104.278 1.00 101.60 ? 131 TYR R O   1 
ATOM 1149 C CB  . TYR B 2 187 ? 122.935 134.890 102.577 1.00 101.60 ? 131 TYR R CB  1 
ATOM 1150 C CG  . TYR B 2 187 ? 123.354 135.466 101.248 1.00 101.60 ? 131 TYR R CG  1 
ATOM 1151 C CD1 . TYR B 2 187 ? 124.552 135.102 100.658 1.00 101.60 ? 131 TYR R CD1 1 
ATOM 1152 C CD2 . TYR B 2 187 ? 122.552 136.382 100.587 1.00 101.60 ? 131 TYR R CD2 1 
ATOM 1153 C CE1 . TYR B 2 187 ? 124.937 135.630 99.444  1.00 101.60 ? 131 TYR R CE1 1 
ATOM 1154 C CE2 . TYR B 2 187 ? 122.929 136.916 99.374  1.00 101.60 ? 131 TYR R CE2 1 
ATOM 1155 C CZ  . TYR B 2 187 ? 124.121 136.537 98.806  1.00 101.60 ? 131 TYR R CZ  1 
ATOM 1156 O OH  . TYR B 2 187 ? 124.500 137.067 97.595  1.00 101.60 ? 131 TYR R OH  1 
ATOM 1157 N N   . SER B 2 188 ? 121.939 132.936 104.836 1.00 101.60 ? 132 SER R N   1 
ATOM 1158 C CA  . SER B 2 188 ? 122.073 132.447 106.201 1.00 101.60 ? 132 SER R CA  1 
ATOM 1159 C C   . SER B 2 188 ? 122.241 130.936 106.239 1.00 101.60 ? 132 SER R C   1 
ATOM 1160 O O   . SER B 2 188 ? 123.051 130.425 107.014 1.00 101.60 ? 132 SER R O   1 
ATOM 1161 C CB  . SER B 2 188 ? 120.862 132.863 107.031 1.00 101.60 ? 132 SER R CB  1 
ATOM 1162 O OG  . SER B 2 188 ? 120.818 134.269 107.181 1.00 101.60 ? 132 SER R OG  1 
ATOM 1163 N N   . GLY B 2 189 ? 121.490 130.203 105.418 1.00 101.60 ? 133 GLY R N   1 
ATOM 1164 C CA  . GLY B 2 189 ? 121.668 128.763 105.376 1.00 101.60 ? 133 GLY R CA  1 
ATOM 1165 C C   . GLY B 2 189 ? 123.074 128.375 104.967 1.00 101.60 ? 133 GLY R C   1 
ATOM 1166 O O   . GLY B 2 189 ? 123.709 127.523 105.599 1.00 101.60 ? 133 GLY R O   1 
ATOM 1167 N N   . ILE B 2 190 ? 123.593 129.008 103.912 1.00 101.60 ? 134 ILE R N   1 
ATOM 1168 C CA  . ILE B 2 190 ? 124.936 128.649 103.465 1.00 101.60 ? 134 ILE R CA  1 
ATOM 1169 C C   . ILE B 2 190 ? 125.964 128.959 104.547 1.00 101.60 ? 134 ILE R C   1 
ATOM 1170 O O   . ILE B 2 190 ? 126.813 128.119 104.887 1.00 101.60 ? 134 ILE R O   1 
ATOM 1171 C CB  . ILE B 2 190 ? 125.278 129.365 102.150 1.00 101.60 ? 134 ILE R CB  1 
ATOM 1172 C CG1 . ILE B 2 190 ? 124.240 129.055 101.072 1.00 101.60 ? 134 ILE R CG1 1 
ATOM 1173 C CG2 . ILE B 2 190 ? 126.653 128.949 101.688 1.00 101.60 ? 134 ILE R CG2 1 
ATOM 1174 C CD1 . ILE B 2 190 ? 124.419 127.708 100.424 1.00 101.60 ? 134 ILE R CD1 1 
ATOM 1175 N N   . LEU B 2 191 ? 125.911 130.165 105.113 1.00 101.60 ? 135 LEU R N   1 
ATOM 1176 C CA  . LEU B 2 191 ? 126.924 130.529 106.094 1.00 101.60 ? 135 LEU R CA  1 
ATOM 1177 C C   . LEU B 2 191 ? 126.768 129.732 107.384 1.00 101.60 ? 135 LEU R C   1 
ATOM 1178 O O   . LEU B 2 191 ? 127.753 129.517 108.097 1.00 101.60 ? 135 LEU R O   1 
ATOM 1179 C CB  . LEU B 2 191 ? 126.871 132.030 106.366 1.00 83.78  ? 135 LEU R CB  1 
ATOM 1180 C CG  . LEU B 2 191 ? 127.167 132.914 105.151 1.00 83.78  ? 135 LEU R CG  1 
ATOM 1181 C CD1 . LEU B 2 191 ? 127.198 134.377 105.547 1.00 83.78  ? 135 LEU R CD1 1 
ATOM 1182 C CD2 . LEU B 2 191 ? 128.476 132.521 104.490 1.00 83.78  ? 135 LEU R CD2 1 
ATOM 1183 N N   . LEU B 2 192 ? 125.560 129.255 107.690 1.00 101.60 ? 136 LEU R N   1 
ATOM 1184 C CA  . LEU B 2 192 ? 125.389 128.376 108.837 1.00 101.60 ? 136 LEU R CA  1 
ATOM 1185 C C   . LEU B 2 192 ? 125.976 127.000 108.586 1.00 101.60 ? 136 LEU R C   1 
ATOM 1186 O O   . LEU B 2 192 ? 126.532 126.401 109.511 1.00 101.60 ? 136 LEU R O   1 
ATOM 1187 C CB  . LEU B 2 192 ? 123.908 128.247 109.187 1.00 101.60 ? 136 LEU R CB  1 
ATOM 1188 C CG  . LEU B 2 192 ? 123.280 129.332 110.062 1.00 101.60 ? 136 LEU R CG  1 
ATOM 1189 C CD1 . LEU B 2 192 ? 121.945 128.843 110.593 1.00 101.60 ? 136 LEU R CD1 1 
ATOM 1190 C CD2 . LEU B 2 192 ? 124.190 129.739 111.209 1.00 101.60 ? 136 LEU R CD2 1 
ATOM 1191 N N   . LEU B 2 193 ? 125.868 126.480 107.363 1.00 101.60 ? 137 LEU R N   1 
ATOM 1192 C CA  . LEU B 2 193 ? 126.616 125.270 107.042 1.00 101.60 ? 137 LEU R CA  1 
ATOM 1193 C C   . LEU B 2 193 ? 128.108 125.493 107.246 1.00 101.60 ? 137 LEU R C   1 
ATOM 1194 O O   . LEU B 2 193 ? 128.796 124.639 107.824 1.00 101.60 ? 137 LEU R O   1 
ATOM 1195 C CB  . LEU B 2 193 ? 126.345 124.833 105.604 1.00 101.60 ? 137 LEU R CB  1 
ATOM 1196 C CG  . LEU B 2 193 ? 124.897 124.531 105.217 1.00 101.60 ? 137 LEU R CG  1 
ATOM 1197 C CD1 . LEU B 2 193 ? 124.851 123.762 103.912 1.00 101.60 ? 137 LEU R CD1 1 
ATOM 1198 C CD2 . LEU B 2 193 ? 124.183 123.767 106.313 1.00 101.60 ? 137 LEU R CD2 1 
ATOM 1199 N N   . ALA B 2 194 ? 128.615 126.644 106.805 1.00 101.60 ? 138 ALA R N   1 
ATOM 1200 C CA  . ALA B 2 194 ? 130.031 126.945 107.001 1.00 101.60 ? 138 ALA R CA  1 
ATOM 1201 C C   . ALA B 2 194 ? 130.391 126.971 108.484 1.00 101.60 ? 138 ALA R C   1 
ATOM 1202 O O   . ALA B 2 194 ? 131.421 126.425 108.896 1.00 101.60 ? 138 ALA R O   1 
ATOM 1203 C CB  . ALA B 2 194 ? 130.379 128.278 106.345 1.00 101.60 ? 138 ALA R CB  1 
ATOM 1204 N N   . CYS B 2 195 ? 129.555 127.611 109.303 1.00 101.60 ? 139 CYS R N   1 
ATOM 1205 C CA  . CYS B 2 195 ? 129.847 127.700 110.731 1.00 101.60 ? 139 CYS R CA  1 
ATOM 1206 C C   . CYS B 2 195 ? 129.778 126.341 111.414 1.00 101.60 ? 139 CYS R C   1 
ATOM 1207 O O   . CYS B 2 195 ? 130.588 126.058 112.303 1.00 101.60 ? 139 CYS R O   1 
ATOM 1208 C CB  . CYS B 2 195 ? 128.889 128.677 111.405 1.00 101.60 ? 139 CYS R CB  1 
ATOM 1209 S SG  . CYS B 2 195 ? 129.214 130.402 111.002 1.00 101.60 ? 139 CYS R SG  1 
ATOM 1210 N N   . ILE B 2 196 ? 128.820 125.493 111.036 1.00 101.60 ? 140 ILE R N   1 
ATOM 1211 C CA  . ILE B 2 196 ? 128.785 124.145 111.594 1.00 101.60 ? 140 ILE R CA  1 
ATOM 1212 C C   . ILE B 2 196 ? 130.059 123.403 111.236 1.00 101.60 ? 140 ILE R C   1 
ATOM 1213 O O   . ILE B 2 196 ? 130.624 122.677 112.065 1.00 101.60 ? 140 ILE R O   1 
ATOM 1214 C CB  . ILE B 2 196 ? 127.537 123.387 111.106 1.00 101.60 ? 140 ILE R CB  1 
ATOM 1215 C CG1 . ILE B 2 196 ? 126.309 123.832 111.895 1.00 101.60 ? 140 ILE R CG1 1 
ATOM 1216 C CG2 . ILE B 2 196 ? 127.735 121.889 111.250 1.00 101.60 ? 140 ILE R CG2 1 
ATOM 1217 C CD1 . ILE B 2 196 ? 125.001 123.348 111.316 1.00 101.60 ? 140 ILE R CD1 1 
ATOM 1218 N N   . SER B 2 197 ? 130.529 123.559 109.999 1.00 101.60 ? 141 SER R N   1 
ATOM 1219 C CA  . SER B 2 197 ? 131.787 122.927 109.622 1.00 101.60 ? 141 SER R CA  1 
ATOM 1220 C C   . SER B 2 197 ? 132.935 123.438 110.482 1.00 101.60 ? 141 SER R C   1 
ATOM 1221 O O   . SER B 2 197 ? 133.791 122.658 110.915 1.00 101.60 ? 141 SER R O   1 
ATOM 1222 C CB  . SER B 2 197 ? 132.075 123.176 108.147 1.00 101.60 ? 141 SER R CB  1 
ATOM 1223 O OG  . SER B 2 197 ? 133.254 122.506 107.751 1.00 101.60 ? 141 SER R OG  1 
ATOM 1224 N N   . VAL B 2 198 ? 132.976 124.747 110.728 1.00 101.60 ? 142 VAL R N   1 
ATOM 1225 C CA  . VAL B 2 198 ? 134.025 125.299 111.580 1.00 101.60 ? 142 VAL R CA  1 
ATOM 1226 C C   . VAL B 2 198 ? 133.953 124.692 112.972 1.00 101.60 ? 142 VAL R C   1 
ATOM 1227 O O   . VAL B 2 198 ? 134.985 124.357 113.569 1.00 101.60 ? 142 VAL R O   1 
ATOM 1228 C CB  . VAL B 2 198 ? 133.923 126.835 111.632 1.00 101.60 ? 142 VAL R CB  1 
ATOM 1229 C CG1 . VAL B 2 198 ? 134.608 127.376 112.874 1.00 101.60 ? 142 VAL R CG1 1 
ATOM 1230 C CG2 . VAL B 2 198 ? 134.536 127.445 110.389 1.00 101.60 ? 142 VAL R CG2 1 
ATOM 1231 N N   . ASP B 2 199 ? 132.746 124.554 113.518 1.00 101.60 ? 143 ASP R N   1 
ATOM 1232 C CA  . ASP B 2 199 ? 132.605 123.952 114.838 1.00 101.60 ? 143 ASP R CA  1 
ATOM 1233 C C   . ASP B 2 199 ? 133.135 122.526 114.847 1.00 101.60 ? 143 ASP R C   1 
ATOM 1234 O O   . ASP B 2 199 ? 133.857 122.133 115.769 1.00 101.60 ? 143 ASP R O   1 
ATOM 1235 C CB  . ASP B 2 199 ? 131.144 123.972 115.280 1.00 101.60 ? 143 ASP R CB  1 
ATOM 1236 C CG  . ASP B 2 199 ? 130.953 123.451 116.691 1.00 101.60 ? 143 ASP R CG  1 
ATOM 1237 O OD1 . ASP B 2 199 ? 131.951 123.058 117.327 1.00 101.60 ? 143 ASP R OD1 1 
ATOM 1238 O OD2 . ASP B 2 199 ? 129.799 123.424 117.163 1.00 101.60 ? 143 ASP R OD2 1 
ATOM 1239 N N   . ARG B 2 200 ? 132.790 121.734 113.832 1.00 101.60 ? 144 ARG R N   1 
ATOM 1240 C CA  . ARG B 2 200 ? 133.279 120.359 113.800 1.00 101.60 ? 144 ARG R CA  1 
ATOM 1241 C C   . ARG B 2 200 ? 134.797 120.312 113.696 1.00 101.60 ? 144 ARG R C   1 
ATOM 1242 O O   . ARG B 2 200 ? 135.439 119.490 114.364 1.00 101.60 ? 144 ARG R O   1 
ATOM 1243 C CB  . ARG B 2 200 ? 132.636 119.593 112.647 1.00 101.60 ? 144 ARG R CB  1 
ATOM 1244 C CG  . ARG B 2 200 ? 131.274 119.027 112.999 1.00 101.60 ? 144 ARG R CG  1 
ATOM 1245 C CD  . ARG B 2 200 ? 130.432 118.766 111.770 1.00 101.60 ? 144 ARG R CD  1 
ATOM 1246 N NE  . ARG B 2 200 ? 129.124 118.229 112.123 1.00 101.60 ? 144 ARG R NE  1 
ATOM 1247 C CZ  . ARG B 2 200 ? 128.154 117.984 111.254 1.00 101.60 ? 144 ARG R CZ  1 
ATOM 1248 N NH1 . ARG B 2 200 ? 128.306 118.222 109.963 1.00 101.60 ? 144 ARG R NH1 1 
ATOM 1249 N NH2 . ARG B 2 200 ? 127.001 117.491 111.693 1.00 101.60 ? 144 ARG R NH2 1 
ATOM 1250 N N   . TYR B 2 201 ? 135.388 121.185 112.881 1.00 101.60 ? 145 TYR R N   1 
ATOM 1251 C CA  . TYR B 2 201 ? 136.841 121.213 112.766 1.00 101.60 ? 145 TYR R CA  1 
ATOM 1252 C C   . TYR B 2 201 ? 137.494 121.570 114.091 1.00 101.60 ? 145 TYR R C   1 
ATOM 1253 O O   . TYR B 2 201 ? 138.491 120.956 114.483 1.00 101.60 ? 145 TYR R O   1 
ATOM 1254 C CB  . TYR B 2 201 ? 137.275 122.204 111.691 1.00 101.60 ? 145 TYR R CB  1 
ATOM 1255 C CG  . TYR B 2 201 ? 138.737 122.566 111.773 1.00 101.60 ? 145 TYR R CG  1 
ATOM 1256 C CD1 . TYR B 2 201 ? 139.719 121.635 111.480 1.00 101.60 ? 145 TYR R CD1 1 
ATOM 1257 C CD2 . TYR B 2 201 ? 139.134 123.836 112.152 1.00 101.60 ? 145 TYR R CD2 1 
ATOM 1258 C CE1 . TYR B 2 201 ? 141.054 121.962 111.554 1.00 101.60 ? 145 TYR R CE1 1 
ATOM 1259 C CE2 . TYR B 2 201 ? 140.466 124.172 112.230 1.00 101.60 ? 145 TYR R CE2 1 
ATOM 1260 C CZ  . TYR B 2 201 ? 141.422 123.232 111.930 1.00 101.60 ? 145 TYR R CZ  1 
ATOM 1261 O OH  . TYR B 2 201 ? 142.752 123.567 112.008 1.00 101.60 ? 145 TYR R OH  1 
ATOM 1262 N N   . LEU B 2 202 ? 136.956 122.565 114.792 1.00 101.60 ? 146 LEU R N   1 
ATOM 1263 C CA  . LEU B 2 202 ? 137.525 122.934 116.083 1.00 101.60 ? 146 LEU R CA  1 
ATOM 1264 C C   . LEU B 2 202 ? 137.197 121.930 117.176 1.00 101.60 ? 146 LEU R C   1 
ATOM 1265 O O   . LEU B 2 202 ? 137.812 121.987 118.246 1.00 101.60 ? 146 LEU R O   1 
ATOM 1266 C CB  . LEU B 2 202 ? 137.035 124.319 116.502 1.00 101.60 ? 146 LEU R CB  1 
ATOM 1267 C CG  . LEU B 2 202 ? 137.503 125.483 115.632 1.00 101.60 ? 146 LEU R CG  1 
ATOM 1268 C CD1 . LEU B 2 202 ? 136.955 126.791 116.169 1.00 101.60 ? 146 LEU R CD1 1 
ATOM 1269 C CD2 . LEU B 2 202 ? 139.016 125.526 115.556 1.00 101.60 ? 146 LEU R CD2 1 
ATOM 1270 N N   . ALA B 2 203 ? 136.251 121.025 116.942 1.00 101.60 ? 147 ALA R N   1 
ATOM 1271 C CA  . ALA B 2 203 ? 135.871 120.032 117.936 1.00 101.60 ? 147 ALA R CA  1 
ATOM 1272 C C   . ALA B 2 203 ? 136.643 118.728 117.814 1.00 101.60 ? 147 ALA R C   1 
ATOM 1273 O O   . ALA B 2 203 ? 136.959 118.113 118.835 1.00 101.60 ? 147 ALA R O   1 
ATOM 1274 C CB  . ALA B 2 203 ? 134.372 119.739 117.836 1.00 101.60 ? 147 ALA R CB  1 
ATOM 1275 N N   . ILE B 2 204 ? 136.953 118.281 116.599 1.00 101.60 ? 148 ILE R N   1 
ATOM 1276 C CA  . ILE B 2 204 ? 137.611 116.985 116.442 1.00 101.60 ? 148 ILE R CA  1 
ATOM 1277 C C   . ILE B 2 204 ? 139.107 117.132 116.189 1.00 101.60 ? 148 ILE R C   1 
ATOM 1278 O O   . ILE B 2 204 ? 139.886 116.248 116.548 1.00 101.60 ? 148 ILE R O   1 
ATOM 1279 C CB  . ILE B 2 204 ? 136.932 116.174 115.325 1.00 101.60 ? 148 ILE R CB  1 
ATOM 1280 C CG1 . ILE B 2 204 ? 135.466 115.927 115.675 1.00 101.60 ? 148 ILE R CG1 1 
ATOM 1281 C CG2 . ILE B 2 204 ? 137.654 114.855 115.133 1.00 101.60 ? 148 ILE R CG2 1 
ATOM 1282 C CD1 . ILE B 2 204 ? 134.664 115.286 114.568 1.00 101.60 ? 148 ILE R CD1 1 
ATOM 1283 N N   . VAL B 2 205 ? 139.547 118.224 115.564 1.00 101.60 ? 149 VAL R N   1 
ATOM 1284 C CA  . VAL B 2 205 ? 140.977 118.413 115.330 1.00 101.60 ? 149 VAL R CA  1 
ATOM 1285 C C   . VAL B 2 205 ? 141.637 119.028 116.558 1.00 101.60 ? 149 VAL R C   1 
ATOM 1286 O O   . VAL B 2 205 ? 142.526 118.429 117.173 1.00 101.60 ? 149 VAL R O   1 
ATOM 1287 C CB  . VAL B 2 205 ? 141.213 119.278 114.081 1.00 101.60 ? 149 VAL R CB  1 
ATOM 1288 C CG1 . VAL B 2 205 ? 142.696 119.389 113.794 1.00 101.60 ? 149 VAL R CG1 1 
ATOM 1289 C CG2 . VAL B 2 205 ? 140.486 118.695 112.890 1.00 101.60 ? 149 VAL R CG2 1 
ATOM 1290 N N   . HIS B 2 206 ? 141.218 120.234 116.926 1.00 101.60 ? 150 HIS R N   1 
ATOM 1291 C CA  . HIS B 2 206 ? 141.721 120.907 118.123 1.00 101.60 ? 150 HIS R CA  1 
ATOM 1292 C C   . HIS B 2 206 ? 140.867 120.540 119.334 1.00 101.60 ? 150 HIS R C   1 
ATOM 1293 O O   . HIS B 2 206 ? 140.183 121.372 119.925 1.00 101.60 ? 150 HIS R O   1 
ATOM 1294 C CB  . HIS B 2 206 ? 141.744 122.418 117.910 1.00 101.60 ? 150 HIS R CB  1 
ATOM 1295 C CG  . HIS B 2 206 ? 142.696 122.870 116.847 1.00 101.60 ? 150 HIS R CG  1 
ATOM 1296 N ND1 . HIS B 2 206 ? 143.563 123.926 117.027 1.00 101.60 ? 150 HIS R ND1 1 
ATOM 1297 C CD2 . HIS B 2 206 ? 142.908 122.420 115.589 1.00 101.60 ? 150 HIS R CD2 1 
ATOM 1298 C CE1 . HIS B 2 206 ? 144.273 124.103 115.927 1.00 101.60 ? 150 HIS R CE1 1 
ATOM 1299 N NE2 . HIS B 2 206 ? 143.895 123.202 115.039 1.00 101.60 ? 150 HIS R NE2 1 
ATOM 1300 N N   . ALA B 2 207 ? 140.912 119.263 119.701 1.00 101.60 ? 151 ALA R N   1 
ATOM 1301 C CA  . ALA B 2 207 ? 140.095 118.743 120.789 1.00 101.60 ? 151 ALA R CA  1 
ATOM 1302 C C   . ALA B 2 207 ? 140.824 118.713 122.122 1.00 101.60 ? 151 ALA R C   1 
ATOM 1303 O O   . ALA B 2 207 ? 140.222 119.012 123.157 1.00 101.60 ? 151 ALA R O   1 
ATOM 1304 C CB  . ALA B 2 207 ? 139.610 117.332 120.455 1.00 101.60 ? 151 ALA R CB  1 
ATOM 1305 N N   . THR B 2 208 ? 142.105 118.349 122.127 1.00 101.60 ? 152 THR R N   1 
ATOM 1306 C CA  . THR B 2 208 ? 142.841 118.260 123.380 1.00 101.60 ? 152 THR R CA  1 
ATOM 1307 C C   . THR B 2 208 ? 143.236 119.627 123.921 1.00 101.60 ? 152 THR R C   1 
ATOM 1308 O O   . THR B 2 208 ? 143.405 119.774 125.135 1.00 101.60 ? 152 THR R O   1 
ATOM 1309 C CB  . THR B 2 208 ? 144.095 117.410 123.191 1.00 101.60 ? 152 THR R CB  1 
ATOM 1310 O OG1 . THR B 2 208 ? 143.784 116.262 122.391 1.00 101.60 ? 152 THR R OG1 1 
ATOM 1311 C CG2 . THR B 2 208 ? 144.632 116.954 124.537 1.00 101.60 ? 152 THR R CG2 1 
ATOM 1312 N N   . ARG B 2 209 ? 143.381 120.624 123.057 1.00 101.60 ? 153 ARG R N   1 
ATOM 1313 C CA  . ARG B 2 209 ? 143.960 121.909 123.410 1.00 101.60 ? 153 ARG R CA  1 
ATOM 1314 C C   . ARG B 2 209 ? 142.896 122.813 124.040 1.00 101.60 ? 153 ARG R C   1 
ATOM 1315 O O   . ARG B 2 209 ? 141.733 122.420 124.187 1.00 101.60 ? 153 ARG R O   1 
ATOM 1316 C CB  . ARG B 2 209 ? 144.589 122.532 122.158 1.00 99.13  ? 153 ARG R CB  1 
ATOM 1317 C CG  . ARG B 2 209 ? 145.471 121.581 121.360 1.00 99.13  ? 153 ARG R CG  1 
ATOM 1318 C CD  . ARG B 2 209 ? 146.912 122.054 121.331 1.00 99.13  ? 153 ARG R CD  1 
ATOM 1319 N NE  . ARG B 2 209 ? 147.048 123.359 120.696 1.00 99.13  ? 153 ARG R NE  1 
ATOM 1320 C CZ  . ARG B 2 209 ? 146.821 123.597 119.412 1.00 99.13  ? 153 ARG R CZ  1 
ATOM 1321 N NH1 . ARG B 2 209 ? 146.470 122.631 118.579 1.00 99.13  ? 153 ARG R NH1 1 
ATOM 1322 N NH2 . ARG B 2 209 ? 146.956 124.836 118.949 1.00 99.13  ? 153 ARG R NH2 1 
ATOM 1323 N N   . THR B 2 210 ? 143.290 124.031 124.416 1.00 101.60 ? 154 THR R N   1 
ATOM 1324 C CA  . THR B 2 210 ? 142.383 124.999 125.018 1.00 101.60 ? 154 THR R CA  1 
ATOM 1325 C C   . THR B 2 210 ? 141.651 125.843 123.986 1.00 101.60 ? 154 THR R C   1 
ATOM 1326 O O   . THR B 2 210 ? 140.754 126.607 124.358 1.00 101.60 ? 154 THR R O   1 
ATOM 1327 C CB  . THR B 2 210 ? 143.145 125.926 125.974 1.00 100.89 ? 154 THR R CB  1 
ATOM 1328 O OG1 . THR B 2 210 ? 144.286 126.476 125.305 1.00 100.89 ? 154 THR R OG1 1 
ATOM 1329 C CG2 . THR B 2 210 ? 143.597 125.168 127.211 1.00 100.89 ? 154 THR R CG2 1 
ATOM 1330 N N   . LEU B 2 211 ? 142.007 125.732 122.705 1.00 101.60 ? 155 LEU R N   1 
ATOM 1331 C CA  . LEU B 2 211 ? 141.268 126.445 121.673 1.00 101.60 ? 155 LEU R CA  1 
ATOM 1332 C C   . LEU B 2 211 ? 139.803 126.040 121.640 1.00 101.60 ? 155 LEU R C   1 
ATOM 1333 O O   . LEU B 2 211 ? 138.963 126.827 121.191 1.00 101.60 ? 155 LEU R O   1 
ATOM 1334 C CB  . LEU B 2 211 ? 141.903 126.196 120.307 1.00 96.76  ? 155 LEU R CB  1 
ATOM 1335 C CG  . LEU B 2 211 ? 141.267 126.943 119.135 1.00 96.76  ? 155 LEU R CG  1 
ATOM 1336 C CD1 . LEU B 2 211 ? 141.112 128.422 119.445 1.00 96.76  ? 155 LEU R CD1 1 
ATOM 1337 C CD2 . LEU B 2 211 ? 142.091 126.740 117.878 1.00 96.76  ? 155 LEU R CD2 1 
ATOM 1338 N N   . THR B 2 212 ? 139.480 124.838 122.121 1.00 101.60 ? 156 THR R N   1 
ATOM 1339 C CA  . THR B 2 212 ? 138.098 124.378 122.127 1.00 101.60 ? 156 THR R CA  1 
ATOM 1340 C C   . THR B 2 212 ? 137.195 125.268 122.967 1.00 101.60 ? 156 THR R C   1 
ATOM 1341 O O   . THR B 2 212 ? 135.973 125.222 122.797 1.00 101.60 ? 156 THR R O   1 
ATOM 1342 C CB  . THR B 2 212 ? 138.025 122.943 122.645 1.00 99.51  ? 156 THR R CB  1 
ATOM 1343 O OG1 . THR B 2 212 ? 136.701 122.432 122.452 1.00 99.51  ? 156 THR R OG1 1 
ATOM 1344 C CG2 . THR B 2 212 ? 138.382 122.888 124.124 1.00 99.51  ? 156 THR R CG2 1 
ATOM 1345 N N   . GLN B 2 213 ? 137.760 126.069 123.867 1.00 101.60 ? 157 GLN R N   1 
ATOM 1346 C CA  . GLN B 2 213 ? 136.969 126.999 124.660 1.00 101.60 ? 157 GLN R CA  1 
ATOM 1347 C C   . GLN B 2 213 ? 136.455 128.179 123.846 1.00 101.60 ? 157 GLN R C   1 
ATOM 1348 O O   . GLN B 2 213 ? 135.644 128.956 124.361 1.00 101.60 ? 157 GLN R O   1 
ATOM 1349 C CB  . GLN B 2 213 ? 137.793 127.518 125.843 1.00 100.76 ? 157 GLN R CB  1 
ATOM 1350 C CG  . GLN B 2 213 ? 138.200 126.451 126.847 1.00 100.76 ? 157 GLN R CG  1 
ATOM 1351 C CD  . GLN B 2 213 ? 137.045 125.566 127.277 1.00 100.76 ? 157 GLN R CD  1 
ATOM 1352 O OE1 . GLN B 2 213 ? 136.583 124.717 126.516 1.00 100.76 ? 157 GLN R OE1 1 
ATOM 1353 N NE2 . GLN B 2 213 ? 136.575 125.758 128.504 1.00 100.76 ? 157 GLN R NE2 1 
ATOM 1354 N N   . LYS B 2 214 ? 136.899 128.333 122.597 1.00 101.60 ? 158 LYS R N   1 
ATOM 1355 C CA  . LYS B 2 214 ? 136.489 129.445 121.751 1.00 101.60 ? 158 LYS R CA  1 
ATOM 1356 C C   . LYS B 2 214 ? 135.262 129.119 120.908 1.00 101.60 ? 158 LYS R C   1 
ATOM 1357 O O   . LYS B 2 214 ? 134.868 129.928 120.061 1.00 101.60 ? 158 LYS R O   1 
ATOM 1358 C CB  . LYS B 2 214 ? 137.642 129.869 120.853 1.00 30.00  ? 158 LYS R CB  1 
ATOM 1359 N N   . ARG B 2 215 ? 134.651 127.953 121.115 1.00 101.60 ? 159 ARG R N   1 
ATOM 1360 C CA  . ARG B 2 215 ? 133.469 127.548 120.366 1.00 101.60 ? 159 ARG R CA  1 
ATOM 1361 C C   . ARG B 2 215 ? 132.177 127.818 121.125 1.00 101.60 ? 159 ARG R C   1 
ATOM 1362 O O   . ARG B 2 215 ? 131.104 127.412 120.667 1.00 101.60 ? 159 ARG R O   1 
ATOM 1363 C CB  . ARG B 2 215 ? 133.558 126.065 119.997 1.00 96.47  ? 159 ARG R CB  1 
ATOM 1364 C CG  . ARG B 2 215 ? 133.230 125.110 121.133 1.00 96.47  ? 159 ARG R CG  1 
ATOM 1365 C CD  . ARG B 2 215 ? 133.681 123.697 120.801 1.00 96.47  ? 159 ARG R CD  1 
ATOM 1366 N NE  . ARG B 2 215 ? 132.951 122.691 121.565 1.00 96.47  ? 159 ARG R NE  1 
ATOM 1367 C CZ  . ARG B 2 215 ? 132.209 121.723 121.041 1.00 96.47  ? 159 ARG R CZ  1 
ATOM 1368 N NH1 . ARG B 2 215 ? 132.053 121.594 119.733 1.00 96.47  ? 159 ARG R NH1 1 
ATOM 1369 N NH2 . ARG B 2 215 ? 131.606 120.859 121.853 1.00 96.47  ? 159 ARG R NH2 1 
ATOM 1370 N N   . TYR B 2 216 ? 132.250 128.492 122.273 1.00 101.60 ? 160 TYR R N   1 
ATOM 1371 C CA  . TYR B 2 216 ? 131.075 128.824 123.066 1.00 101.60 ? 160 TYR R CA  1 
ATOM 1372 C C   . TYR B 2 216 ? 130.486 130.178 122.690 1.00 101.60 ? 160 TYR R C   1 
ATOM 1373 O O   . TYR B 2 216 ? 129.772 130.783 123.497 1.00 101.60 ? 160 TYR R O   1 
ATOM 1374 C CB  . TYR B 2 216 ? 131.422 128.795 124.553 1.00 99.11  ? 160 TYR R CB  1 
ATOM 1375 C CG  . TYR B 2 216 ? 131.956 127.463 125.021 1.00 99.11  ? 160 TYR R CG  1 
ATOM 1376 C CD1 . TYR B 2 216 ? 131.238 126.294 124.811 1.00 99.11  ? 160 TYR R CD1 1 
ATOM 1377 C CD2 . TYR B 2 216 ? 133.177 127.373 125.672 1.00 99.11  ? 160 TYR R CD2 1 
ATOM 1378 C CE1 . TYR B 2 216 ? 131.720 125.074 125.236 1.00 99.11  ? 160 TYR R CE1 1 
ATOM 1379 C CE2 . TYR B 2 216 ? 133.668 126.156 126.101 1.00 99.11  ? 160 TYR R CE2 1 
ATOM 1380 C CZ  . TYR B 2 216 ? 132.936 125.010 125.881 1.00 99.11  ? 160 TYR R CZ  1 
ATOM 1381 O OH  . TYR B 2 216 ? 133.421 123.795 126.307 1.00 99.11  ? 160 TYR R OH  1 
ATOM 1382 N N   . LEU B 2 217 ? 130.772 130.665 121.482 1.00 101.60 ? 161 LEU R N   1 
ATOM 1383 C CA  . LEU B 2 217 ? 130.243 131.931 120.990 1.00 101.60 ? 161 LEU R CA  1 
ATOM 1384 C C   . LEU B 2 217 ? 129.124 131.727 119.975 1.00 101.60 ? 161 LEU R C   1 
ATOM 1385 O O   . LEU B 2 217 ? 128.983 132.519 119.038 1.00 101.60 ? 161 LEU R O   1 
ATOM 1386 C CB  . LEU B 2 217 ? 131.367 132.763 120.375 1.00 101.60 ? 161 LEU R CB  1 
ATOM 1387 C CG  . LEU B 2 217 ? 132.683 132.780 121.156 1.00 101.60 ? 161 LEU R CG  1 
ATOM 1388 C CD1 . LEU B 2 217 ? 133.670 133.744 120.518 1.00 101.60 ? 161 LEU R CD1 1 
ATOM 1389 C CD2 . LEU B 2 217 ? 132.442 133.147 122.612 1.00 101.60 ? 161 LEU R CD2 1 
ATOM 1390 N N   . VAL B 2 218 ? 128.323 130.673 120.146 1.00 101.60 ? 162 VAL R N   1 
ATOM 1391 C CA  . VAL B 2 218 ? 127.299 130.356 119.155 1.00 101.60 ? 162 VAL R CA  1 
ATOM 1392 C C   . VAL B 2 218 ? 126.306 131.500 119.030 1.00 101.60 ? 162 VAL R C   1 
ATOM 1393 O O   . VAL B 2 218 ? 125.883 131.852 117.924 1.00 101.60 ? 162 VAL R O   1 
ATOM 1394 C CB  . VAL B 2 218 ? 126.592 129.035 119.511 1.00 92.73  ? 162 VAL R CB  1 
ATOM 1395 C CG1 . VAL B 2 218 ? 127.583 127.891 119.502 1.00 92.73  ? 162 VAL R CG1 1 
ATOM 1396 C CG2 . VAL B 2 218 ? 125.893 129.138 120.857 1.00 92.73  ? 162 VAL R CG2 1 
ATOM 1397 N N   . LYS B 2 219 ? 125.906 132.092 120.155 1.00 101.60 ? 163 LYS R N   1 
ATOM 1398 C CA  . LYS B 2 219 ? 124.975 133.213 120.099 1.00 101.60 ? 163 LYS R CA  1 
ATOM 1399 C C   . LYS B 2 219 ? 125.524 134.326 119.215 1.00 101.60 ? 163 LYS R C   1 
ATOM 1400 O O   . LYS B 2 219 ? 124.857 134.782 118.277 1.00 101.60 ? 163 LYS R O   1 
ATOM 1401 C CB  . LYS B 2 219 ? 124.684 133.735 121.498 1.00 30.00  ? 163 LYS R CB  1 
ATOM 1402 N N   . PHE B 2 220 ? 126.753 134.759 119.492 1.00 101.60 ? 164 PHE R N   1 
ATOM 1403 C CA  . PHE B 2 220 ? 127.334 135.872 118.751 1.00 101.60 ? 164 PHE R CA  1 
ATOM 1404 C C   . PHE B 2 220 ? 127.573 135.498 117.295 1.00 101.60 ? 164 PHE R C   1 
ATOM 1405 O O   . PHE B 2 220 ? 127.311 136.298 116.391 1.00 101.60 ? 164 PHE R O   1 
ATOM 1406 C CB  . PHE B 2 220 ? 128.636 136.319 119.416 1.00 98.82  ? 164 PHE R CB  1 
ATOM 1407 C CG  . PHE B 2 220 ? 128.467 136.781 120.840 1.00 98.82  ? 164 PHE R CG  1 
ATOM 1408 C CD1 . PHE B 2 220 ? 127.219 137.133 121.333 1.00 98.82  ? 164 PHE R CD1 1 
ATOM 1409 C CD2 . PHE B 2 220 ? 129.560 136.863 121.685 1.00 98.82  ? 164 PHE R CD2 1 
ATOM 1410 C CE1 . PHE B 2 220 ? 127.068 137.556 122.637 1.00 98.82  ? 164 PHE R CE1 1 
ATOM 1411 C CE2 . PHE B 2 220 ? 129.413 137.285 122.991 1.00 98.82  ? 164 PHE R CE2 1 
ATOM 1412 C CZ  . PHE B 2 220 ? 128.165 137.632 123.466 1.00 98.82  ? 164 PHE R CZ  1 
ATOM 1413 N N   . ILE B 2 221 ? 128.073 134.287 117.044 1.00 101.60 ? 165 ILE R N   1 
ATOM 1414 C CA  . ILE B 2 221 ? 128.343 133.877 115.668 1.00 101.60 ? 165 ILE R CA  1 
ATOM 1415 C C   . ILE B 2 221 ? 127.053 133.843 114.863 1.00 101.60 ? 165 ILE R C   1 
ATOM 1416 O O   . ILE B 2 221 ? 126.999 134.325 113.727 1.00 101.60 ? 165 ILE R O   1 
ATOM 1417 C CB  . ILE B 2 221 ? 129.056 132.514 115.642 1.00 101.60 ? 165 ILE R CB  1 
ATOM 1418 C CG1 . ILE B 2 221 ? 130.433 132.618 116.297 1.00 101.60 ? 165 ILE R CG1 1 
ATOM 1419 C CG2 . ILE B 2 221 ? 129.191 132.019 114.216 1.00 101.60 ? 165 ILE R CG2 1 
ATOM 1420 C CD1 . ILE B 2 221 ? 130.970 131.293 116.785 1.00 101.60 ? 165 ILE R CD1 1 
ATOM 1421 N N   . CYS B 2 222 ? 125.995 133.269 115.436 1.00 101.60 ? 166 CYS R N   1 
ATOM 1422 C CA  . CYS B 2 222 ? 124.721 133.190 114.731 1.00 101.60 ? 166 CYS R CA  1 
ATOM 1423 C C   . CYS B 2 222 ? 124.143 134.576 114.481 1.00 101.60 ? 166 CYS R C   1 
ATOM 1424 O O   . CYS B 2 222 ? 123.646 134.860 113.382 1.00 101.60 ? 166 CYS R O   1 
ATOM 1425 C CB  . CYS B 2 222 ? 123.744 132.336 115.533 1.00 101.60 ? 166 CYS R CB  1 
ATOM 1426 S SG  . CYS B 2 222 ? 124.047 130.569 115.382 1.00 101.60 ? 166 CYS R SG  1 
ATOM 1427 N N   . LEU B 2 223 ? 124.197 135.456 115.483 1.00 101.60 ? 167 LEU R N   1 
ATOM 1428 C CA  . LEU B 2 223 ? 123.687 136.805 115.283 1.00 101.60 ? 167 LEU R CA  1 
ATOM 1429 C C   . LEU B 2 223 ? 124.477 137.524 114.199 1.00 101.60 ? 167 LEU R C   1 
ATOM 1430 O O   . LEU B 2 223 ? 123.900 138.211 113.349 1.00 101.60 ? 167 LEU R O   1 
ATOM 1431 C CB  . LEU B 2 223 ? 123.729 137.590 116.585 1.00 30.00  ? 167 LEU R CB  1 
ATOM 1432 N N   . SER B 2 224 ? 125.801 137.368 114.205 1.00 101.60 ? 168 SER R N   1 
ATOM 1433 C CA  . SER B 2 224 ? 126.626 138.005 113.188 1.00 101.60 ? 168 SER R CA  1 
ATOM 1434 C C   . SER B 2 224 ? 126.299 137.471 111.802 1.00 101.60 ? 168 SER R C   1 
ATOM 1435 O O   . SER B 2 224 ? 126.260 138.232 110.832 1.00 101.60 ? 168 SER R O   1 
ATOM 1436 C CB  . SER B 2 224 ? 128.105 137.793 113.507 1.00 101.60 ? 168 SER R CB  1 
ATOM 1437 O OG  . SER B 2 224 ? 128.927 138.274 112.459 1.00 101.60 ? 168 SER R OG  1 
ATOM 1438 N N   . ILE B 2 225 ? 126.078 136.162 111.685 1.00 101.60 ? 169 ILE R N   1 
ATOM 1439 C CA  . ILE B 2 225 ? 125.753 135.589 110.383 1.00 101.60 ? 169 ILE R CA  1 
ATOM 1440 C C   . ILE B 2 225 ? 124.420 136.127 109.884 1.00 101.60 ? 169 ILE R C   1 
ATOM 1441 O O   . ILE B 2 225 ? 124.287 136.509 108.714 1.00 101.60 ? 169 ILE R O   1 
ATOM 1442 C CB  . ILE B 2 225 ? 125.750 134.054 110.461 1.00 101.60 ? 169 ILE R CB  1 
ATOM 1443 C CG1 . ILE B 2 225 ? 127.172 133.528 110.667 1.00 101.60 ? 169 ILE R CG1 1 
ATOM 1444 C CG2 . ILE B 2 225 ? 125.128 133.461 109.213 1.00 101.60 ? 169 ILE R CG2 1 
ATOM 1445 C CD1 . ILE B 2 225 ? 128.120 133.812 109.521 1.00 101.60 ? 169 ILE R CD1 1 
ATOM 1446 N N   . TRP B 2 226 ? 123.409 136.165 110.756 1.00 101.60 ? 170 TRP R N   1 
ATOM 1447 C CA  . TRP B 2 226 ? 122.128 136.733 110.353 1.00 101.60 ? 170 TRP R CA  1 
ATOM 1448 C C   . TRP B 2 226 ? 122.286 138.182 109.918 1.00 101.60 ? 170 TRP R C   1 
ATOM 1449 O O   . TRP B 2 226 ? 121.721 138.591 108.897 1.00 101.60 ? 170 TRP R O   1 
ATOM 1450 C CB  . TRP B 2 226 ? 121.118 136.636 111.497 1.00 101.60 ? 170 TRP R CB  1 
ATOM 1451 C CG  . TRP B 2 226 ? 120.490 135.285 111.646 1.00 101.60 ? 170 TRP R CG  1 
ATOM 1452 C CD1 . TRP B 2 226 ? 120.795 134.341 112.579 1.00 101.60 ? 170 TRP R CD1 1 
ATOM 1453 C CD2 . TRP B 2 226 ? 119.438 134.734 110.848 1.00 101.60 ? 170 TRP R CD2 1 
ATOM 1454 N NE1 . TRP B 2 226 ? 120.005 133.233 112.407 1.00 101.60 ? 170 TRP R NE1 1 
ATOM 1455 C CE2 . TRP B 2 226 ? 119.162 133.449 111.351 1.00 101.60 ? 170 TRP R CE2 1 
ATOM 1456 C CE3 . TRP B 2 226 ? 118.704 135.201 109.755 1.00 101.60 ? 170 TRP R CE3 1 
ATOM 1457 C CZ2 . TRP B 2 226 ? 118.187 132.626 110.799 1.00 101.60 ? 170 TRP R CZ2 1 
ATOM 1458 C CZ3 . TRP B 2 226 ? 117.736 134.381 109.208 1.00 101.60 ? 170 TRP R CZ3 1 
ATOM 1459 C CH2 . TRP B 2 226 ? 117.486 133.109 109.730 1.00 101.60 ? 170 TRP R CH2 1 
ATOM 1460 N N   . GLY B 2 227 ? 123.062 138.967 110.667 1.00 101.60 ? 171 GLY R N   1 
ATOM 1461 C CA  . GLY B 2 227 ? 123.242 140.365 110.310 1.00 101.60 ? 171 GLY R CA  1 
ATOM 1462 C C   . GLY B 2 227 ? 123.962 140.538 108.986 1.00 101.60 ? 171 GLY R C   1 
ATOM 1463 O O   . GLY B 2 227 ? 123.596 141.390 108.173 1.00 101.60 ? 171 GLY R O   1 
ATOM 1464 N N   . LEU B 2 228 ? 125.007 139.742 108.758 1.00 101.60 ? 172 LEU R N   1 
ATOM 1465 C CA  . LEU B 2 228 ? 125.743 139.840 107.504 1.00 101.60 ? 172 LEU R CA  1 
ATOM 1466 C C   . LEU B 2 228 ? 124.865 139.444 106.327 1.00 101.60 ? 172 LEU R C   1 
ATOM 1467 O O   . LEU B 2 228 ? 124.908 140.086 105.272 1.00 101.60 ? 172 LEU R O   1 
ATOM 1468 C CB  . LEU B 2 228 ? 126.999 138.970 107.559 1.00 101.60 ? 172 LEU R CB  1 
ATOM 1469 C CG  . LEU B 2 228 ? 127.798 138.853 106.258 1.00 101.60 ? 172 LEU R CG  1 
ATOM 1470 C CD1 . LEU B 2 228 ? 128.412 140.188 105.881 1.00 101.60 ? 172 LEU R CD1 1 
ATOM 1471 C CD2 . LEU B 2 228 ? 128.878 137.797 106.395 1.00 101.60 ? 172 LEU R CD2 1 
ATOM 1472 N N   . SER B 2 229 ? 124.063 138.391 106.483 1.00 101.60 ? 173 SER R N   1 
ATOM 1473 C CA  . SER B 2 229 ? 123.140 138.015 105.418 1.00 101.60 ? 173 SER R CA  1 
ATOM 1474 C C   . SER B 2 229 ? 122.143 139.134 105.147 1.00 101.60 ? 173 SER R C   1 
ATOM 1475 O O   . SER B 2 229 ? 121.867 139.476 103.989 1.00 101.60 ? 173 SER R O   1 
ATOM 1476 C CB  . SER B 2 229 ? 122.415 136.724 105.792 1.00 101.60 ? 173 SER R CB  1 
ATOM 1477 O OG  . SER B 2 229 ? 123.333 135.662 105.979 1.00 101.60 ? 173 SER R OG  1 
ATOM 1478 N N   . LEU B 2 230 ? 121.587 139.718 106.210 1.00 101.60 ? 174 LEU R N   1 
ATOM 1479 C CA  . LEU B 2 230 ? 120.642 140.814 106.039 1.00 101.60 ? 174 LEU R CA  1 
ATOM 1480 C C   . LEU B 2 230 ? 121.284 141.961 105.272 1.00 101.60 ? 174 LEU R C   1 
ATOM 1481 O O   . LEU B 2 230 ? 120.711 142.477 104.307 1.00 101.60 ? 174 LEU R O   1 
ATOM 1482 C CB  . LEU B 2 230 ? 120.129 141.293 107.389 1.00 30.00  ? 174 LEU R CB  1 
ATOM 1483 N N   . LEU B 2 231 ? 122.490 142.359 105.677 1.00 101.60 ? 175 LEU R N   1 
ATOM 1484 C CA  . LEU B 2 231 ? 123.169 143.457 105.001 1.00 101.60 ? 175 LEU R CA  1 
ATOM 1485 C C   . LEU B 2 231 ? 123.462 143.118 103.547 1.00 101.60 ? 175 LEU R C   1 
ATOM 1486 O O   . LEU B 2 231 ? 123.323 143.979 102.670 1.00 101.60 ? 175 LEU R O   1 
ATOM 1487 C CB  . LEU B 2 231 ? 124.463 143.804 105.736 1.00 101.60 ? 175 LEU R CB  1 
ATOM 1488 C CG  . LEU B 2 231 ? 125.418 144.763 105.021 1.00 101.60 ? 175 LEU R CG  1 
ATOM 1489 C CD1 . LEU B 2 231 ? 124.842 146.167 105.014 1.00 101.60 ? 175 LEU R CD1 1 
ATOM 1490 C CD2 . LEU B 2 231 ? 126.787 144.743 105.678 1.00 101.60 ? 175 LEU R CD2 1 
ATOM 1491 N N   . LEU B 2 232 ? 123.871 141.883 103.269 1.00 101.60 ? 176 LEU R N   1 
ATOM 1492 C CA  . LEU B 2 232 ? 124.205 141.471 101.915 1.00 101.60 ? 176 LEU R CA  1 
ATOM 1493 C C   . LEU B 2 232 ? 122.984 141.336 101.019 1.00 101.60 ? 176 LEU R C   1 
ATOM 1494 O O   . LEU B 2 232 ? 123.130 141.376 99.794  1.00 101.60 ? 176 LEU R O   1 
ATOM 1495 C CB  . LEU B 2 232 ? 124.954 140.132 101.943 1.00 101.60 ? 176 LEU R CB  1 
ATOM 1496 C CG  . LEU B 2 232 ? 126.418 140.132 102.395 1.00 101.60 ? 176 LEU R CG  1 
ATOM 1497 C CD1 . LEU B 2 232 ? 127.048 138.774 102.129 1.00 101.60 ? 176 LEU R CD1 1 
ATOM 1498 C CD2 . LEU B 2 232 ? 127.218 141.223 101.702 1.00 101.60 ? 176 LEU R CD2 1 
ATOM 1499 N N   . ALA B 2 233 ? 121.794 141.166 101.591 1.00 101.60 ? 177 ALA R N   1 
ATOM 1500 C CA  . ALA B 2 233 ? 120.582 140.989 100.802 1.00 101.60 ? 177 ALA R CA  1 
ATOM 1501 C C   . ALA B 2 233 ? 119.856 142.297 100.511 1.00 101.60 ? 177 ALA R C   1 
ATOM 1502 O O   . ALA B 2 233 ? 118.850 142.285 99.796  1.00 101.60 ? 177 ALA R O   1 
ATOM 1503 C CB  . ALA B 2 233 ? 119.638 140.019 101.510 1.00 101.60 ? 177 ALA R CB  1 
ATOM 1504 N N   . LEU B 2 234 ? 120.336 143.423 101.036 1.00 101.60 ? 178 LEU R N   1 
ATOM 1505 C CA  . LEU B 2 234 ? 119.665 144.705 100.832 1.00 101.60 ? 178 LEU R CA  1 
ATOM 1506 C C   . LEU B 2 234 ? 119.672 145.150 99.372  1.00 101.60 ? 178 LEU R C   1 
ATOM 1507 O O   . LEU B 2 234 ? 118.755 145.869 98.953  1.00 101.60 ? 178 LEU R O   1 
ATOM 1508 C CB  . LEU B 2 234 ? 120.306 145.792 101.695 1.00 101.60 ? 178 LEU R CB  1 
ATOM 1509 C CG  . LEU B 2 234 ? 119.922 145.801 103.176 1.00 101.60 ? 178 LEU R CG  1 
ATOM 1510 C CD1 . LEU B 2 234 ? 120.675 146.898 103.904 1.00 101.60 ? 178 LEU R CD1 1 
ATOM 1511 C CD2 . LEU B 2 234 ? 118.422 145.978 103.354 1.00 101.60 ? 178 LEU R CD2 1 
ATOM 1512 N N   . PRO B 2 235 ? 120.679 144.787 98.572  1.00 101.60 ? 179 PRO R N   1 
ATOM 1513 C CA  . PRO B 2 235 ? 120.617 145.147 97.148  1.00 101.60 ? 179 PRO R CA  1 
ATOM 1514 C C   . PRO B 2 235 ? 119.356 144.645 96.475  1.00 101.60 ? 179 PRO R C   1 
ATOM 1515 O O   . PRO B 2 235 ? 118.831 145.302 95.569  1.00 101.60 ? 179 PRO R O   1 
ATOM 1516 C CB  . PRO B 2 235 ? 121.877 144.492 96.575  1.00 101.60 ? 179 PRO R CB  1 
ATOM 1517 C CG  . PRO B 2 235 ? 122.822 144.493 97.708  1.00 101.60 ? 179 PRO R CG  1 
ATOM 1518 C CD  . PRO B 2 235 ? 121.983 144.193 98.914  1.00 101.60 ? 179 PRO R CD  1 
ATOM 1519 N N   . VAL B 2 236 ? 118.855 143.486 96.900  1.00 101.60 ? 180 VAL R N   1 
ATOM 1520 C CA  . VAL B 2 236 ? 117.591 142.989 96.373  1.00 101.60 ? 180 VAL R CA  1 
ATOM 1521 C C   . VAL B 2 236 ? 116.446 143.913 96.767  1.00 101.60 ? 180 VAL R C   1 
ATOM 1522 O O   . VAL B 2 236 ? 115.597 144.259 95.938  1.00 101.60 ? 180 VAL R O   1 
ATOM 1523 C CB  . VAL B 2 236 ? 117.355 141.547 96.857  1.00 101.60 ? 180 VAL R CB  1 
ATOM 1524 C CG1 . VAL B 2 236 ? 115.872 141.235 96.939  1.00 101.60 ? 180 VAL R CG1 1 
ATOM 1525 C CG2 . VAL B 2 236 ? 118.062 140.562 95.937  1.00 101.60 ? 180 VAL R CG2 1 
ATOM 1526 N N   . LEU B 2 237 ? 116.401 144.331 98.034  1.00 101.60 ? 181 LEU R N   1 
ATOM 1527 C CA  . LEU B 2 237 ? 115.309 145.187 98.486  1.00 101.60 ? 181 LEU R CA  1 
ATOM 1528 C C   . LEU B 2 237 ? 115.317 146.530 97.768  1.00 101.60 ? 181 LEU R C   1 
ATOM 1529 O O   . LEU B 2 237 ? 114.259 147.044 97.390  1.00 101.60 ? 181 LEU R O   1 
ATOM 1530 C CB  . LEU B 2 237 ? 115.395 145.396 99.997  1.00 101.60 ? 181 LEU R CB  1 
ATOM 1531 C CG  . LEU B 2 237 ? 114.233 146.168 100.627 1.00 101.60 ? 181 LEU R CG  1 
ATOM 1532 C CD1 . LEU B 2 237 ? 113.026 145.271 100.809 1.00 101.60 ? 181 LEU R CD1 1 
ATOM 1533 C CD2 . LEU B 2 237 ? 114.656 146.765 101.955 1.00 101.60 ? 181 LEU R CD2 1 
ATOM 1534 N N   . LEU B 2 238 ? 116.499 147.118 97.578  1.00 101.60 ? 182 LEU R N   1 
ATOM 1535 C CA  . LEU B 2 238 ? 116.563 148.463 97.017  1.00 101.60 ? 182 LEU R CA  1 
ATOM 1536 C C   . LEU B 2 238 ? 116.245 148.473 95.527  1.00 101.60 ? 182 LEU R C   1 
ATOM 1537 O O   . LEU B 2 238 ? 115.592 149.400 95.035  1.00 101.60 ? 182 LEU R O   1 
ATOM 1538 C CB  . LEU B 2 238 ? 117.942 149.070 97.262  1.00 101.60 ? 182 LEU R CB  1 
ATOM 1539 C CG  . LEU B 2 238 ? 118.371 149.188 98.722  1.00 101.60 ? 182 LEU R CG  1 
ATOM 1540 C CD1 . LEU B 2 238 ? 119.823 149.628 98.806  1.00 101.60 ? 182 LEU R CD1 1 
ATOM 1541 C CD2 . LEU B 2 238 ? 117.469 150.156 99.472  1.00 101.60 ? 182 LEU R CD2 1 
ATOM 1542 N N   . PHE B 2 239 ? 116.694 147.459 94.793  1.00 101.93 ? 183 PHE R N   1 
ATOM 1543 C CA  . PHE B 2 239 ? 116.747 147.515 93.338  1.00 101.93 ? 183 PHE R CA  1 
ATOM 1544 C C   . PHE B 2 239 ? 116.025 146.336 92.696  1.00 101.93 ? 183 PHE R C   1 
ATOM 1545 O O   . PHE B 2 239 ? 116.545 145.690 91.786  1.00 101.93 ? 183 PHE R O   1 
ATOM 1546 C CB  . PHE B 2 239 ? 118.198 147.570 92.872  1.00 101.93 ? 183 PHE R CB  1 
ATOM 1547 C CG  . PHE B 2 239 ? 119.057 148.485 93.693  1.00 101.93 ? 183 PHE R CG  1 
ATOM 1548 C CD1 . PHE B 2 239 ? 118.759 149.832 93.793  1.00 101.93 ? 183 PHE R CD1 1 
ATOM 1549 C CD2 . PHE B 2 239 ? 120.158 147.998 94.373  1.00 101.93 ? 183 PHE R CD2 1 
ATOM 1550 C CE1 . PHE B 2 239 ? 119.545 150.675 94.551  1.00 101.93 ? 183 PHE R CE1 1 
ATOM 1551 C CE2 . PHE B 2 239 ? 120.947 148.838 95.132  1.00 101.93 ? 183 PHE R CE2 1 
ATOM 1552 C CZ  . PHE B 2 239 ? 120.640 150.176 95.221  1.00 101.93 ? 183 PHE R CZ  1 
ATOM 1553 N N   . ARG B 2 240 ? 114.812 146.038 93.158  1.00 102.61 ? 184 ARG R N   1 
ATOM 1554 C CA  . ARG B 2 240 ? 113.968 145.021 92.541  1.00 102.61 ? 184 ARG R CA  1 
ATOM 1555 C C   . ARG B 2 240 ? 112.563 145.580 92.399  1.00 102.61 ? 184 ARG R C   1 
ATOM 1556 O O   . ARG B 2 240 ? 111.984 146.064 93.376  1.00 102.61 ? 184 ARG R O   1 
ATOM 1557 C CB  . ARG B 2 240 ? 113.946 143.734 93.367  1.00 102.61 ? 184 ARG R CB  1 
ATOM 1558 C CG  . ARG B 2 240 ? 115.072 142.768 93.044  1.00 102.61 ? 184 ARG R CG  1 
ATOM 1559 C CD  . ARG B 2 240 ? 114.678 141.334 93.353  1.00 102.61 ? 184 ARG R CD  1 
ATOM 1560 N NE  . ARG B 2 240 ? 115.808 140.421 93.220  1.00 102.61 ? 184 ARG R NE  1 
ATOM 1561 C CZ  . ARG B 2 240 ? 115.749 139.218 92.665  1.00 102.61 ? 184 ARG R CZ  1 
ATOM 1562 N NH1 . ARG B 2 240 ? 114.618 138.729 92.180  1.00 102.61 ? 184 ARG R NH1 1 
ATOM 1563 N NH2 . ARG B 2 240 ? 116.854 138.482 92.596  1.00 102.61 ? 184 ARG R NH2 1 
ATOM 1564 N N   . ARG B 2 241 ? 112.015 145.509 91.189  1.00 107.71 ? 185 ARG R N   1 
ATOM 1565 C CA  . ARG B 2 241 ? 110.670 145.990 90.919  1.00 107.71 ? 185 ARG R CA  1 
ATOM 1566 C C   . ARG B 2 241 ? 110.077 145.188 89.772  1.00 107.71 ? 185 ARG R C   1 
ATOM 1567 O O   . ARG B 2 241 ? 110.796 144.569 88.985  1.00 107.71 ? 185 ARG R O   1 
ATOM 1568 C CB  . ARG B 2 241 ? 110.665 147.490 90.584  1.00 107.71 ? 185 ARG R CB  1 
ATOM 1569 C CG  . ARG B 2 241 ? 110.933 147.810 89.120  1.00 107.71 ? 185 ARG R CG  1 
ATOM 1570 C CD  . ARG B 2 241 ? 110.888 149.301 88.854  1.00 107.71 ? 185 ARG R CD  1 
ATOM 1571 N NE  . ARG B 2 241 ? 110.554 149.589 87.465  1.00 107.71 ? 185 ARG R NE  1 
ATOM 1572 C CZ  . ARG B 2 241 ? 110.457 150.808 86.952  1.00 107.71 ? 185 ARG R CZ  1 
ATOM 1573 N NH1 . ARG B 2 241 ? 110.659 151.887 87.690  1.00 107.71 ? 185 ARG R NH1 1 
ATOM 1574 N NH2 . ARG B 2 241 ? 110.150 150.948 85.666  1.00 107.71 ? 185 ARG R NH2 1 
ATOM 1575 N N   . THR B 2 242 ? 108.750 145.208 89.680  1.00 103.50 ? 186 THR R N   1 
ATOM 1576 C CA  . THR B 2 242 ? 108.077 144.556 88.567  1.00 103.50 ? 186 THR R CA  1 
ATOM 1577 C C   . THR B 2 242 ? 108.515 145.192 87.256  1.00 103.50 ? 186 THR R C   1 
ATOM 1578 O O   . THR B 2 242 ? 108.553 146.419 87.131  1.00 103.50 ? 186 THR R O   1 
ATOM 1579 C CB  . THR B 2 242 ? 106.562 144.666 88.723  1.00 103.50 ? 186 THR R CB  1 
ATOM 1580 O OG1 . THR B 2 242 ? 106.178 146.046 88.696  1.00 103.50 ? 186 THR R OG1 1 
ATOM 1581 C CG2 . THR B 2 242 ? 106.111 144.046 90.034  1.00 103.50 ? 186 THR R CG2 1 
ATOM 1582 N N   . VAL B 2 243 ? 108.846 144.357 86.276  1.00 106.26 ? 187 VAL R N   1 
ATOM 1583 C CA  . VAL B 2 243 ? 109.342 144.815 84.985  1.00 106.26 ? 187 VAL R CA  1 
ATOM 1584 C C   . VAL B 2 243 ? 108.383 144.353 83.901  1.00 106.26 ? 187 VAL R C   1 
ATOM 1585 O O   . VAL B 2 243 ? 107.962 143.191 83.884  1.00 106.26 ? 187 VAL R O   1 
ATOM 1586 C CB  . VAL B 2 243 ? 110.767 144.301 84.707  1.00 106.26 ? 187 VAL R CB  1 
ATOM 1587 C CG1 . VAL B 2 243 ? 111.138 144.535 83.253  1.00 106.26 ? 187 VAL R CG1 1 
ATOM 1588 C CG2 . VAL B 2 243 ? 111.756 144.979 85.631  1.00 106.26 ? 187 VAL R CG2 1 
ATOM 1589 N N   . TYR B 2 244 ? 108.050 145.263 82.990  1.00 105.84 ? 188 TYR R N   1 
ATOM 1590 C CA  . TYR B 2 244 ? 107.085 145.014 81.931  1.00 105.84 ? 188 TYR R CA  1 
ATOM 1591 C C   . TYR B 2 244 ? 107.788 144.999 80.583  1.00 105.84 ? 188 TYR R C   1 
ATOM 1592 O O   . TYR B 2 244 ? 108.744 145.749 80.361  1.00 105.84 ? 188 TYR R O   1 
ATOM 1593 C CB  . TYR B 2 244 ? 105.986 146.080 81.923  1.00 105.84 ? 188 TYR R CB  1 
ATOM 1594 C CG  . TYR B 2 244 ? 104.935 145.892 82.991  1.00 105.84 ? 188 TYR R CG  1 
ATOM 1595 C CD1 . TYR B 2 244 ? 104.144 144.753 83.022  1.00 105.84 ? 188 TYR R CD1 1 
ATOM 1596 C CD2 . TYR B 2 244 ? 104.733 146.856 83.966  1.00 105.84 ? 188 TYR R CD2 1 
ATOM 1597 C CE1 . TYR B 2 244 ? 103.183 144.579 83.996  1.00 105.84 ? 188 TYR R CE1 1 
ATOM 1598 C CE2 . TYR B 2 244 ? 103.775 146.692 84.944  1.00 105.84 ? 188 TYR R CE2 1 
ATOM 1599 C CZ  . TYR B 2 244 ? 103.002 145.552 84.955  1.00 105.84 ? 188 TYR R CZ  1 
ATOM 1600 O OH  . TYR B 2 244 ? 102.046 145.386 85.928  1.00 105.84 ? 188 TYR R OH  1 
ATOM 1601 N N   . SER B 2 245 ? 107.314 144.137 79.690  1.00 113.86 ? 189 SER R N   1 
ATOM 1602 C CA  . SER B 2 245 ? 107.798 144.066 78.321  1.00 113.86 ? 189 SER R CA  1 
ATOM 1603 C C   . SER B 2 245 ? 106.694 143.499 77.437  1.00 113.86 ? 189 SER R C   1 
ATOM 1604 O O   . SER B 2 245 ? 105.822 142.755 77.894  1.00 113.86 ? 189 SER R O   1 
ATOM 1605 C CB  . SER B 2 245 ? 109.071 143.216 78.234  1.00 113.86 ? 189 SER R CB  1 
ATOM 1606 O OG  . SER B 2 245 ? 110.090 143.761 79.052  1.00 113.86 ? 189 SER R OG  1 
ATOM 1607 N N   . SER B 2 246 ? 106.736 143.853 76.155  1.00 118.33 ? 190 SER R N   1 
ATOM 1608 C CA  . SER B 2 246 ? 105.708 143.435 75.211  1.00 118.33 ? 190 SER R CA  1 
ATOM 1609 C C   . SER B 2 246 ? 105.723 141.942 74.928  1.00 118.33 ? 190 SER R C   1 
ATOM 1610 O O   . SER B 2 246 ? 104.655 141.345 74.764  1.00 118.33 ? 190 SER R O   1 
ATOM 1611 C CB  . SER B 2 246 ? 105.864 144.193 73.888  1.00 118.33 ? 190 SER R CB  1 
ATOM 1612 O OG  . SER B 2 246 ? 105.701 145.588 74.077  1.00 118.33 ? 190 SER R OG  1 
ATOM 1613 N N   . ASN B 2 247 ? 106.902 141.325 74.868  1.00 120.24 ? 191 ASN R N   1 
ATOM 1614 C CA  . ASN B 2 247 ? 107.003 139.906 74.555  1.00 120.24 ? 191 ASN R CA  1 
ATOM 1615 C C   . ASN B 2 247 ? 107.243 139.034 75.779  1.00 120.24 ? 191 ASN R C   1 
ATOM 1616 O O   . ASN B 2 247 ? 107.006 137.822 75.711  1.00 120.24 ? 191 ASN R O   1 
ATOM 1617 C CB  . ASN B 2 247 ? 108.126 139.670 73.541  1.00 120.24 ? 191 ASN R CB  1 
ATOM 1618 C CG  . ASN B 2 247 ? 109.421 140.345 73.937  1.00 120.24 ? 191 ASN R CG  1 
ATOM 1619 O OD1 . ASN B 2 247 ? 109.707 140.515 75.120  1.00 120.24 ? 191 ASN R OD1 1 
ATOM 1620 N ND2 . ASN B 2 247 ? 110.213 140.735 72.946  1.00 120.24 ? 191 ASN R ND2 1 
ATOM 1621 N N   . VAL B 2 248 ? 107.699 139.608 76.889  1.00 114.70 ? 192 VAL R N   1 
ATOM 1622 C CA  . VAL B 2 248 ? 107.970 138.861 78.111  1.00 114.70 ? 192 VAL R CA  1 
ATOM 1623 C C   . VAL B 2 248 ? 106.909 139.212 79.143  1.00 114.70 ? 192 VAL R C   1 
ATOM 1624 O O   . VAL B 2 248 ? 106.590 140.388 79.345  1.00 114.70 ? 192 VAL R O   1 
ATOM 1625 C CB  . VAL B 2 248 ? 109.377 139.154 78.672  1.00 114.70 ? 192 VAL R CB  1 
ATOM 1626 C CG1 . VAL B 2 248 ? 109.721 138.157 79.763  1.00 114.70 ? 192 VAL R CG1 1 
ATOM 1627 C CG2 . VAL B 2 248 ? 110.418 139.123 77.567  1.00 114.70 ? 192 VAL R CG2 1 
ATOM 1628 N N   . SER B 2 249 ? 106.367 138.187 79.795  1.00 110.75 ? 193 SER R N   1 
ATOM 1629 C CA  . SER B 2 249 ? 105.370 138.399 80.825  1.00 110.75 ? 193 SER R CA  1 
ATOM 1630 C C   . SER B 2 249 ? 106.021 138.970 82.083  1.00 110.75 ? 193 SER R C   1 
ATOM 1631 O O   . SER B 2 249 ? 107.239 138.897 82.253  1.00 110.75 ? 193 SER R O   1 
ATOM 1632 C CB  . SER B 2 249 ? 104.658 137.091 81.148  1.00 110.75 ? 193 SER R CB  1 
ATOM 1633 O OG  . SER B 2 249 ? 105.543 136.175 81.766  1.00 110.75 ? 193 SER R OG  1 
ATOM 1634 N N   . PRO B 2 250 ? 105.225 139.545 82.980  1.00 105.50 ? 194 PRO R N   1 
ATOM 1635 C CA  . PRO B 2 250 ? 105.797 140.204 84.158  1.00 105.50 ? 194 PRO R CA  1 
ATOM 1636 C C   . PRO B 2 250 ? 106.629 139.255 85.004  1.00 105.50 ? 194 PRO R C   1 
ATOM 1637 O O   . PRO B 2 250 ? 106.333 138.067 85.140  1.00 105.50 ? 194 PRO R O   1 
ATOM 1638 C CB  . PRO B 2 250 ? 104.559 140.685 84.922  1.00 105.50 ? 194 PRO R CB  1 
ATOM 1639 C CG  . PRO B 2 250 ? 103.519 140.833 83.865  1.00 105.50 ? 194 PRO R CG  1 
ATOM 1640 C CD  . PRO B 2 250 ? 103.758 139.659 82.970  1.00 105.50 ? 194 PRO R CD  1 
ATOM 1641 N N   . ALA B 2 251 ? 107.694 139.807 85.578  1.00 104.16 ? 195 ALA R N   1 
ATOM 1642 C CA  . ALA B 2 251 ? 108.547 139.064 86.494  1.00 104.16 ? 195 ALA R CA  1 
ATOM 1643 C C   . ALA B 2 251 ? 109.232 140.056 87.423  1.00 104.16 ? 195 ALA R C   1 
ATOM 1644 O O   . ALA B 2 251 ? 109.508 141.198 87.051  1.00 104.16 ? 195 ALA R O   1 
ATOM 1645 C CB  . ALA B 2 251 ? 109.572 138.216 85.739  1.00 104.16 ? 195 ALA R CB  1 
ATOM 1646 N N   . CYS B 2 252 ? 109.510 139.596 88.643  1.00 105.66 ? 196 CYS R N   1 
ATOM 1647 C CA  . CYS B 2 252 ? 110.115 140.437 89.678  1.00 105.66 ? 196 CYS R CA  1 
ATOM 1648 C C   . CYS B 2 252 ? 111.620 140.541 89.420  1.00 105.66 ? 196 CYS R C   1 
ATOM 1649 O O   . CYS B 2 252 ? 112.447 139.838 90.003  1.00 105.66 ? 196 CYS R O   1 
ATOM 1650 C CB  . CYS B 2 252 ? 109.792 139.875 91.060  1.00 105.66 ? 196 CYS R CB  1 
ATOM 1651 S SG  . CYS B 2 252 ? 110.850 140.400 92.435  1.00 105.66 ? 196 CYS R SG  1 
ATOM 1652 N N   . TYR B 2 253 ? 111.959 141.453 88.509  1.00 109.11 ? 197 TYR R N   1 
ATOM 1653 C CA  . TYR B 2 253 ? 113.321 141.643 88.034  1.00 109.11 ? 197 TYR R CA  1 
ATOM 1654 C C   . TYR B 2 253 ? 113.945 142.873 88.695  1.00 109.11 ? 197 TYR R C   1 
ATOM 1655 O O   . TYR B 2 253 ? 113.329 143.534 89.535  1.00 109.11 ? 197 TYR R O   1 
ATOM 1656 C CB  . TYR B 2 253 ? 113.316 141.761 86.511  1.00 109.11 ? 197 TYR R CB  1 
ATOM 1657 C CG  . TYR B 2 253 ? 114.628 141.417 85.848  1.00 109.11 ? 197 TYR R CG  1 
ATOM 1658 C CD1 . TYR B 2 253 ? 115.220 140.180 86.033  1.00 109.11 ? 197 TYR R CD1 1 
ATOM 1659 C CD2 . TYR B 2 253 ? 115.269 142.332 85.028  1.00 109.11 ? 197 TYR R CD2 1 
ATOM 1660 C CE1 . TYR B 2 253 ? 116.417 139.866 85.426  1.00 109.11 ? 197 TYR R CE1 1 
ATOM 1661 C CE2 . TYR B 2 253 ? 116.465 142.027 84.416  1.00 109.11 ? 197 TYR R CE2 1 
ATOM 1662 C CZ  . TYR B 2 253 ? 117.034 140.792 84.618  1.00 109.11 ? 197 TYR R CZ  1 
ATOM 1663 O OH  . TYR B 2 253 ? 118.228 140.479 84.011  1.00 109.11 ? 197 TYR R OH  1 
ATOM 1664 N N   . GLU B 2 254 ? 115.181 143.194 88.319  1.00 110.22 ? 198 GLU R N   1 
ATOM 1665 C CA  . GLU B 2 254 ? 115.893 144.352 88.838  1.00 110.22 ? 198 GLU R CA  1 
ATOM 1666 C C   . GLU B 2 254 ? 115.618 145.578 87.976  1.00 110.22 ? 198 GLU R C   1 
ATOM 1667 O O   . GLU B 2 254 ? 115.343 145.471 86.779  1.00 110.22 ? 198 GLU R O   1 
ATOM 1668 C CB  . GLU B 2 254 ? 117.403 144.103 88.885  1.00 110.22 ? 198 GLU R CB  1 
ATOM 1669 C CG  . GLU B 2 254 ? 117.886 143.293 90.079  1.00 110.22 ? 198 GLU R CG  1 
ATOM 1670 C CD  . GLU B 2 254 ? 117.899 141.800 89.820  1.00 110.22 ? 198 GLU R CD  1 
ATOM 1671 O OE1 . GLU B 2 254 ? 117.616 141.384 88.678  1.00 110.22 ? 198 GLU R OE1 1 
ATOM 1672 O OE2 . GLU B 2 254 ? 118.201 141.038 90.762  1.00 110.22 ? 198 GLU R OE2 1 
ATOM 1673 N N   . ASP B 2 255 ? 115.692 146.750 88.603  1.00 113.95 ? 199 ASP R N   1 
ATOM 1674 C CA  . ASP B 2 255 ? 115.592 148.039 87.920  1.00 113.95 ? 199 ASP R CA  1 
ATOM 1675 C C   . ASP B 2 255 ? 116.694 148.935 88.478  1.00 113.95 ? 199 ASP R C   1 
ATOM 1676 O O   . ASP B 2 255 ? 116.482 149.670 89.445  1.00 113.95 ? 199 ASP R O   1 
ATOM 1677 C CB  . ASP B 2 255 ? 114.210 148.661 88.107  1.00 113.95 ? 199 ASP R CB  1 
ATOM 1678 C CG  . ASP B 2 255 ? 114.080 150.013 87.434  1.00 113.95 ? 199 ASP R CG  1 
ATOM 1679 O OD1 . ASP B 2 255 ? 114.794 150.953 87.840  1.00 113.95 ? 199 ASP R OD1 1 
ATOM 1680 O OD2 . ASP B 2 255 ? 113.263 150.139 86.499  1.00 113.95 ? 199 ASP R OD2 1 
ATOM 1681 N N   . MET B 2 256 ? 117.872 148.874 87.860  1.00 114.41 ? 200 MET R N   1 
ATOM 1682 C CA  . MET B 2 256 ? 119.020 149.654 88.297  1.00 114.41 ? 200 MET R CA  1 
ATOM 1683 C C   . MET B 2 256 ? 119.385 150.776 87.333  1.00 114.41 ? 200 MET R C   1 
ATOM 1684 O O   . MET B 2 256 ? 120.254 151.590 87.661  1.00 114.41 ? 200 MET R O   1 
ATOM 1685 C CB  . MET B 2 256 ? 120.230 148.734 88.490  1.00 114.41 ? 200 MET R CB  1 
ATOM 1686 C CG  . MET B 2 256 ? 120.286 148.084 89.864  1.00 114.41 ? 200 MET R CG  1 
ATOM 1687 S SD  . MET B 2 256 ? 121.729 147.031 90.106  1.00 114.41 ? 200 MET R SD  1 
ATOM 1688 C CE  . MET B 2 256 ? 121.492 145.831 88.802  1.00 114.41 ? 200 MET R CE  1 
ATOM 1689 N N   . GLY B 2 257 ? 118.751 150.845 86.175  1.00 119.14 ? 201 GLY R N   1 
ATOM 1690 C CA  . GLY B 2 257 ? 119.046 151.865 85.192  1.00 119.14 ? 201 GLY R CA  1 
ATOM 1691 C C   . GLY B 2 257 ? 118.901 151.298 83.795  1.00 119.14 ? 201 GLY R C   1 
ATOM 1692 O O   . GLY B 2 257 ? 118.527 150.143 83.619  1.00 119.14 ? 201 GLY R O   1 
ATOM 1693 N N   . ASN B 2 258 ? 119.214 152.132 82.802  1.00 127.18 ? 202 ASN R N   1 
ATOM 1694 C CA  . ASN B 2 258 ? 119.109 151.720 81.410  1.00 127.18 ? 202 ASN R CA  1 
ATOM 1695 C C   . ASN B 2 258 ? 120.190 150.731 80.998  1.00 127.18 ? 202 ASN R C   1 
ATOM 1696 O O   . ASN B 2 258 ? 119.990 149.991 80.029  1.00 127.18 ? 202 ASN R O   1 
ATOM 1697 C CB  . ASN B 2 258 ? 119.172 152.941 80.485  1.00 127.18 ? 202 ASN R CB  1 
ATOM 1698 C CG  . ASN B 2 258 ? 117.918 153.793 80.558  1.00 127.18 ? 202 ASN R CG  1 
ATOM 1699 O OD1 . ASN B 2 258 ? 117.983 154.991 80.830  1.00 127.18 ? 202 ASN R OD1 1 
ATOM 1700 N ND2 . ASN B 2 258 ? 116.767 153.174 80.322  1.00 127.18 ? 202 ASN R ND2 1 
ATOM 1701 N N   . ASN B 2 259 ? 121.322 150.701 81.702  1.00 122.27 ? 203 ASN R N   1 
ATOM 1702 C CA  . ASN B 2 259 ? 122.365 149.706 81.488  1.00 122.27 ? 203 ASN R CA  1 
ATOM 1703 C C   . ASN B 2 259 ? 122.352 148.651 82.589  1.00 122.27 ? 203 ASN R C   1 
ATOM 1704 O O   . ASN B 2 259 ? 123.402 148.144 82.991  1.00 122.27 ? 203 ASN R O   1 
ATOM 1705 C CB  . ASN B 2 259 ? 123.735 150.375 81.403  1.00 122.27 ? 203 ASN R CB  1 
ATOM 1706 C CG  . ASN B 2 259 ? 123.888 151.232 80.162  1.00 122.27 ? 203 ASN R CG  1 
ATOM 1707 O OD1 . ASN B 2 259 ? 124.143 152.433 80.250  1.00 122.27 ? 203 ASN R OD1 1 
ATOM 1708 N ND2 . ASN B 2 259 ? 123.737 150.617 78.996  1.00 122.27 ? 203 ASN R ND2 1 
ATOM 1709 N N   . THR B 2 260 ? 121.160 148.315 83.082  1.00 116.82 ? 204 THR R N   1 
ATOM 1710 C CA  . THR B 2 260 ? 121.049 147.395 84.208  1.00 116.82 ? 204 THR R CA  1 
ATOM 1711 C C   . THR B 2 260 ? 121.585 146.015 83.854  1.00 116.82 ? 204 THR R C   1 
ATOM 1712 O O   . THR B 2 260 ? 122.017 145.263 84.736  1.00 116.82 ? 204 THR R O   1 
ATOM 1713 C CB  . THR B 2 260 ? 119.590 147.302 84.656  1.00 116.82 ? 204 THR R CB  1 
ATOM 1714 O OG1 . THR B 2 260 ? 119.180 148.552 85.224  1.00 116.82 ? 204 THR R OG1 1 
ATOM 1715 C CG2 . THR B 2 260 ? 119.411 146.200 85.687  1.00 116.82 ? 204 THR R CG2 1 
ATOM 1716 N N   . ALA B 2 261 ? 121.554 145.656 82.569  1.00 117.65 ? 205 ALA R N   1 
ATOM 1717 C CA  . ALA B 2 261 ? 121.998 144.333 82.150  1.00 117.65 ? 205 ALA R CA  1 
ATOM 1718 C C   . ALA B 2 261 ? 123.411 144.046 82.644  1.00 117.65 ? 205 ALA R C   1 
ATOM 1719 O O   . ALA B 2 261 ? 123.682 142.987 83.220  1.00 117.65 ? 205 ALA R O   1 
ATOM 1720 C CB  . ALA B 2 261 ? 121.925 144.221 80.625  1.00 117.65 ? 205 ALA R CB  1 
ATOM 1721 N N   . ASN B 2 262 ? 124.325 144.991 82.426  1.00 116.96 ? 206 ASN R N   1 
ATOM 1722 C CA  . ASN B 2 262 ? 125.690 144.817 82.909  1.00 116.96 ? 206 ASN R CA  1 
ATOM 1723 C C   . ASN B 2 262 ? 125.748 144.869 84.430  1.00 116.96 ? 206 ASN R C   1 
ATOM 1724 O O   . ASN B 2 262 ? 126.500 144.114 85.056  1.00 116.96 ? 206 ASN R O   1 
ATOM 1725 C CB  . ASN B 2 262 ? 126.596 145.883 82.296  1.00 116.96 ? 206 ASN R CB  1 
ATOM 1726 C CG  . ASN B 2 262 ? 126.527 145.903 80.783  1.00 116.96 ? 206 ASN R CG  1 
ATOM 1727 O OD1 . ASN B 2 262 ? 125.827 145.095 80.172  1.00 116.96 ? 206 ASN R OD1 1 
ATOM 1728 N ND2 . ASN B 2 262 ? 127.253 146.828 80.170  1.00 116.96 ? 206 ASN R ND2 1 
ATOM 1729 N N   . TRP B 2 263 ? 124.954 145.749 85.045  1.00 114.53 ? 207 TRP R N   1 
ATOM 1730 C CA  . TRP B 2 263 ? 125.011 145.910 86.495  1.00 114.53 ? 207 TRP R CA  1 
ATOM 1731 C C   . TRP B 2 263 ? 124.655 144.614 87.211  1.00 114.53 ? 207 TRP R C   1 
ATOM 1732 O O   . TRP B 2 263 ? 125.229 144.295 88.262  1.00 114.53 ? 207 TRP R O   1 
ATOM 1733 C CB  . TRP B 2 263 ? 124.073 147.034 86.930  1.00 114.53 ? 207 TRP R CB  1 
ATOM 1734 C CG  . TRP B 2 263 ? 124.637 148.402 86.716  1.00 114.53 ? 207 TRP R CG  1 
ATOM 1735 C CD1 . TRP B 2 263 ? 124.137 149.376 85.905  1.00 114.53 ? 207 TRP R CD1 1 
ATOM 1736 C CD2 . TRP B 2 263 ? 125.809 148.954 87.329  1.00 114.53 ? 207 TRP R CD2 1 
ATOM 1737 N NE1 . TRP B 2 263 ? 124.924 150.499 85.972  1.00 114.53 ? 207 TRP R NE1 1 
ATOM 1738 C CE2 . TRP B 2 263 ? 125.958 150.265 86.840  1.00 114.53 ? 207 TRP R CE2 1 
ATOM 1739 C CE3 . TRP B 2 263 ? 126.747 148.465 88.242  1.00 114.53 ? 207 TRP R CE3 1 
ATOM 1740 C CZ2 . TRP B 2 263 ? 127.005 151.094 87.232  1.00 114.53 ? 207 TRP R CZ2 1 
ATOM 1741 C CZ3 . TRP B 2 263 ? 127.786 149.289 88.631  1.00 114.53 ? 207 TRP R CZ3 1 
ATOM 1742 C CH2 . TRP B 2 263 ? 127.906 150.588 88.126  1.00 114.53 ? 207 TRP R CH2 1 
ATOM 1743 N N   . ARG B 2 264 ? 123.696 143.863 86.671  1.00 112.23 ? 208 ARG R N   1 
ATOM 1744 C CA  . ARG B 2 264 ? 123.341 142.593 87.292  1.00 112.23 ? 208 ARG R CA  1 
ATOM 1745 C C   . ARG B 2 264 ? 124.531 141.646 87.300  1.00 112.23 ? 208 ARG R C   1 
ATOM 1746 O O   . ARG B 2 264 ? 124.664 140.817 88.204  1.00 112.23 ? 208 ARG R O   1 
ATOM 1747 C CB  . ARG B 2 264 ? 122.154 141.958 86.570  1.00 112.23 ? 208 ARG R CB  1 
ATOM 1748 C CG  . ARG B 2 264 ? 120.885 142.790 86.628  1.00 112.23 ? 208 ARG R CG  1 
ATOM 1749 C CD  . ARG B 2 264 ? 119.695 142.079 86.006  1.00 112.23 ? 208 ARG R CD  1 
ATOM 1750 N NE  . ARG B 2 264 ? 119.124 141.075 86.897  1.00 112.23 ? 208 ARG R NE  1 
ATOM 1751 C CZ  . ARG B 2 264 ? 119.533 139.817 86.983  1.00 112.23 ? 208 ARG R CZ  1 
ATOM 1752 N NH1 . ARG B 2 264 ? 120.488 139.341 86.200  1.00 112.23 ? 208 ARG R NH1 1 
ATOM 1753 N NH2 . ARG B 2 264 ? 118.961 139.010 87.871  1.00 112.23 ? 208 ARG R NH2 1 
ATOM 1754 N N   . MET B 2 265 ? 125.410 141.755 86.303  1.00 112.58 ? 209 MET R N   1 
ATOM 1755 C CA  . MET B 2 265 ? 126.604 140.919 86.296  1.00 112.58 ? 209 MET R CA  1 
ATOM 1756 C C   . MET B 2 265 ? 127.467 141.194 87.519  1.00 112.58 ? 209 MET R C   1 
ATOM 1757 O O   . MET B 2 265 ? 127.907 140.262 88.201  1.00 112.58 ? 209 MET R O   1 
ATOM 1758 C CB  . MET B 2 265 ? 127.406 141.153 85.018  1.00 112.58 ? 209 MET R CB  1 
ATOM 1759 C CG  . MET B 2 265 ? 126.629 140.889 83.746  1.00 112.58 ? 209 MET R CG  1 
ATOM 1760 S SD  . MET B 2 265 ? 127.614 141.189 82.268  1.00 112.58 ? 209 MET R SD  1 
ATOM 1761 C CE  . MET B 2 265 ? 128.130 139.523 81.865  1.00 112.58 ? 209 MET R CE  1 
ATOM 1762 N N   . LEU B 2 266 ? 127.714 142.470 87.818  1.00 112.46 ? 210 LEU R N   1 
ATOM 1763 C CA  . LEU B 2 266 ? 128.481 142.804 89.012  1.00 112.46 ? 210 LEU R CA  1 
ATOM 1764 C C   . LEU B 2 266 ? 127.749 142.359 90.269  1.00 112.46 ? 210 LEU R C   1 
ATOM 1765 O O   . LEU B 2 266 ? 128.369 141.839 91.203  1.00 112.46 ? 210 LEU R O   1 
ATOM 1766 C CB  . LEU B 2 266 ? 128.762 144.305 89.055  1.00 112.46 ? 210 LEU R CB  1 
ATOM 1767 C CG  . LEU B 2 266 ? 129.371 144.914 87.789  1.00 112.46 ? 210 LEU R CG  1 
ATOM 1768 C CD1 . LEU B 2 266 ? 129.843 146.334 88.055  1.00 112.46 ? 210 LEU R CD1 1 
ATOM 1769 C CD2 . LEU B 2 266 ? 130.516 144.060 87.266  1.00 112.46 ? 210 LEU R CD2 1 
ATOM 1770 N N   . LEU B 2 267 ? 126.429 142.548 90.311  1.00 105.67 ? 211 LEU R N   1 
ATOM 1771 C CA  . LEU B 2 267 ? 125.673 142.109 91.480  1.00 105.67 ? 211 LEU R CA  1 
ATOM 1772 C C   . LEU B 2 267 ? 125.812 140.609 91.702  1.00 105.67 ? 211 LEU R C   1 
ATOM 1773 O O   . LEU B 2 267 ? 125.896 140.156 92.849  1.00 105.67 ? 211 LEU R O   1 
ATOM 1774 C CB  . LEU B 2 267 ? 124.196 142.481 91.333  1.00 105.67 ? 211 LEU R CB  1 
ATOM 1775 C CG  . LEU B 2 267 ? 123.725 143.810 91.930  1.00 105.67 ? 211 LEU R CG  1 
ATOM 1776 C CD1 . LEU B 2 267 ? 122.209 143.875 91.917  1.00 105.67 ? 211 LEU R CD1 1 
ATOM 1777 C CD2 . LEU B 2 267 ? 124.241 144.007 93.346  1.00 105.67 ? 211 LEU R CD2 1 
ATOM 1778 N N   . ARG B 2 268 ? 125.844 139.826 90.624  1.00 102.84 ? 212 ARG R N   1 
ATOM 1779 C CA  . ARG B 2 268 ? 125.913 138.377 90.759  1.00 102.84 ? 212 ARG R CA  1 
ATOM 1780 C C   . ARG B 2 268 ? 127.206 137.916 91.410  1.00 102.84 ? 212 ARG R C   1 
ATOM 1781 O O   . ARG B 2 268 ? 127.263 136.787 91.907  1.00 102.84 ? 212 ARG R O   1 
ATOM 1782 C CB  . ARG B 2 268 ? 125.767 137.714 89.391  1.00 102.84 ? 212 ARG R CB  1 
ATOM 1783 C CG  . ARG B 2 268 ? 124.386 137.147 89.124  1.00 102.84 ? 212 ARG R CG  1 
ATOM 1784 C CD  . ARG B 2 268 ? 124.452 135.962 88.188  1.00 102.84 ? 212 ARG R CD  1 
ATOM 1785 N NE  . ARG B 2 268 ? 124.885 136.358 86.852  1.00 102.84 ? 212 ARG R NE  1 
ATOM 1786 C CZ  . ARG B 2 268 ? 124.259 136.048 85.724  1.00 102.84 ? 212 ARG R CZ  1 
ATOM 1787 N NH1 . ARG B 2 268 ? 123.147 135.330 85.719  1.00 102.84 ? 212 ARG R NH1 1 
ATOM 1788 N NH2 . ARG B 2 268 ? 124.764 136.468 84.569  1.00 102.84 ? 212 ARG R NH2 1 
ATOM 1789 N N   . ILE B 2 269 ? 128.242 138.755 91.424  1.00 101.60 ? 213 ILE R N   1 
ATOM 1790 C CA  . ILE B 2 269 ? 129.492 138.349 92.055  1.00 101.60 ? 213 ILE R CA  1 
ATOM 1791 C C   . ILE B 2 269 ? 129.287 138.112 93.544  1.00 101.60 ? 213 ILE R C   1 
ATOM 1792 O O   . ILE B 2 269 ? 130.051 137.369 94.171  1.00 101.60 ? 213 ILE R O   1 
ATOM 1793 C CB  . ILE B 2 269 ? 130.588 139.398 91.791  1.00 101.60 ? 213 ILE R CB  1 
ATOM 1794 C CG1 . ILE B 2 269 ? 131.941 138.713 91.599  1.00 101.60 ? 213 ILE R CG1 1 
ATOM 1795 C CG2 . ILE B 2 269 ? 130.665 140.406 92.929  1.00 101.60 ? 213 ILE R CG2 1 
ATOM 1796 C CD1 . ILE B 2 269 ? 132.984 139.604 90.970  1.00 101.60 ? 213 ILE R CD1 1 
ATOM 1797 N N   . LEU B 2 270 ? 128.261 138.734 94.139  1.00 101.60 ? 214 LEU R N   1 
ATOM 1798 C CA  . LEU B 2 270 ? 128.012 138.526 95.566  1.00 101.60 ? 214 LEU R CA  1 
ATOM 1799 C C   . LEU B 2 270 ? 127.553 137.103 95.850  1.00 101.60 ? 214 LEU R C   1 
ATOM 1800 O O   . LEU B 2 270 ? 128.262 136.372 96.564  1.00 101.60 ? 214 LEU R O   1 
ATOM 1801 C CB  . LEU B 2 270 ? 127.014 139.565 96.078  1.00 101.60 ? 214 LEU R CB  1 
ATOM 1802 C CG  . LEU B 2 270 ? 127.565 140.983 96.214  1.00 101.60 ? 214 LEU R CG  1 
ATOM 1803 C CD1 . LEU B 2 270 ? 126.436 141.978 96.421  1.00 101.60 ? 214 LEU R CD1 1 
ATOM 1804 C CD2 . LEU B 2 270 ? 128.561 141.056 97.358  1.00 101.60 ? 214 LEU R CD2 1 
ATOM 1805 N N   . PRO B 2 271 ? 126.411 136.640 95.339  1.00 101.60 ? 215 PRO R N   1 
ATOM 1806 C CA  . PRO B 2 271 ? 125.973 135.274 95.663  1.00 101.60 ? 215 PRO R CA  1 
ATOM 1807 C C   . PRO B 2 271 ? 126.964 134.205 95.252  1.00 101.60 ? 215 PRO R C   1 
ATOM 1808 O O   . PRO B 2 271 ? 127.017 133.154 95.900  1.00 101.60 ? 215 PRO R O   1 
ATOM 1809 C CB  . PRO B 2 271 ? 124.651 135.132 94.898  1.00 101.60 ? 215 PRO R CB  1 
ATOM 1810 C CG  . PRO B 2 271 ? 124.662 136.211 93.880  1.00 101.60 ? 215 PRO R CG  1 
ATOM 1811 C CD  . PRO B 2 271 ? 125.456 137.329 94.459  1.00 101.60 ? 215 PRO R CD  1 
ATOM 1812 N N   . GLN B 2 272 ? 127.748 134.427 94.201  1.00 101.60 ? 216 GLN R N   1 
ATOM 1813 C CA  . GLN B 2 272 ? 128.704 133.437 93.729  1.00 101.60 ? 216 GLN R CA  1 
ATOM 1814 C C   . GLN B 2 272 ? 130.058 133.534 94.418  1.00 101.60 ? 216 GLN R C   1 
ATOM 1815 O O   . GLN B 2 272 ? 130.933 132.709 94.144  1.00 101.60 ? 216 GLN R O   1 
ATOM 1816 C CB  . GLN B 2 272 ? 128.893 133.564 92.216  1.00 101.60 ? 216 GLN R CB  1 
ATOM 1817 C CG  . GLN B 2 272 ? 127.649 133.231 91.417  1.00 101.60 ? 216 GLN R CG  1 
ATOM 1818 C CD  . GLN B 2 272 ? 127.968 132.750 90.019  1.00 101.60 ? 216 GLN R CD  1 
ATOM 1819 O OE1 . GLN B 2 272 ? 128.060 133.544 89.084  1.00 101.60 ? 216 GLN R OE1 1 
ATOM 1820 N NE2 . GLN B 2 272 ? 128.140 131.442 89.867  1.00 101.60 ? 216 GLN R NE2 1 
ATOM 1821 N N   . SER B 2 273 ? 130.253 134.511 95.301  1.00 101.60 ? 217 SER R N   1 
ATOM 1822 C CA  . SER B 2 273 ? 131.512 134.668 96.019  1.00 101.60 ? 217 SER R CA  1 
ATOM 1823 C C   . SER B 2 273 ? 131.378 134.345 97.497  1.00 101.60 ? 217 SER R C   1 
ATOM 1824 O O   . SER B 2 273 ? 132.118 133.500 98.011  1.00 101.60 ? 217 SER R O   1 
ATOM 1825 C CB  . SER B 2 273 ? 132.042 136.097 95.843  1.00 101.60 ? 217 SER R CB  1 
ATOM 1826 O OG  . SER B 2 273 ? 131.049 137.049 96.178  1.00 101.60 ? 217 SER R OG  1 
ATOM 1827 N N   . PHE B 2 274 ? 130.453 134.995 98.199  1.00 101.60 ? 218 PHE R N   1 
ATOM 1828 C CA  . PHE B 2 274 ? 130.147 134.661 99.580  1.00 101.60 ? 218 PHE R CA  1 
ATOM 1829 C C   . PHE B 2 274 ? 129.003 133.663 99.694  1.00 101.60 ? 218 PHE R C   1 
ATOM 1830 O O   . PHE B 2 274 ? 128.436 133.505 100.780 1.00 101.60 ? 218 PHE R O   1 
ATOM 1831 C CB  . PHE B 2 274 ? 129.819 135.928 100.372 1.00 101.60 ? 218 PHE R CB  1 
ATOM 1832 C CG  . PHE B 2 274 ? 131.027 136.729 100.756 1.00 101.60 ? 218 PHE R CG  1 
ATOM 1833 C CD1 . PHE B 2 274 ? 131.654 137.549 99.838  1.00 101.60 ? 218 PHE R CD1 1 
ATOM 1834 C CD2 . PHE B 2 274 ? 131.542 136.652 102.038 1.00 101.60 ? 218 PHE R CD2 1 
ATOM 1835 C CE1 . PHE B 2 274 ? 132.770 138.286 100.194 1.00 101.60 ? 218 PHE R CE1 1 
ATOM 1836 C CE2 . PHE B 2 274 ? 132.656 137.383 102.400 1.00 101.60 ? 218 PHE R CE2 1 
ATOM 1837 C CZ  . PHE B 2 274 ? 133.270 138.201 101.477 1.00 101.60 ? 218 PHE R CZ  1 
ATOM 1838 N N   . GLY B 2 275 ? 128.652 132.992 98.601  1.00 101.60 ? 219 GLY R N   1 
ATOM 1839 C CA  . GLY B 2 275 ? 127.576 132.024 98.626  1.00 101.60 ? 219 GLY R CA  1 
ATOM 1840 C C   . GLY B 2 275 ? 128.006 130.641 98.187  1.00 101.60 ? 219 GLY R C   1 
ATOM 1841 O O   . GLY B 2 275 ? 127.349 129.654 98.527  1.00 101.60 ? 219 GLY R O   1 
ATOM 1842 N N   . PHE B 2 276 ? 129.085 130.548 97.410  1.00 86.82  ? 220 PHE R N   1 
ATOM 1843 C CA  . PHE B 2 276 ? 129.585 129.242 96.998  1.00 86.82  ? 220 PHE R CA  1 
ATOM 1844 C C   . PHE B 2 276 ? 131.084 129.083 97.214  1.00 86.82  ? 220 PHE R C   1 
ATOM 1845 O O   . PHE B 2 276 ? 131.540 128.010 97.619  1.00 86.82  ? 220 PHE R O   1 
ATOM 1846 C CB  . PHE B 2 276 ? 129.262 128.986 95.529  1.00 86.82  ? 220 PHE R CB  1 
ATOM 1847 C CG  . PHE B 2 276 ? 129.504 127.571 95.104  1.00 86.82  ? 220 PHE R CG  1 
ATOM 1848 C CD1 . PHE B 2 276 ? 128.641 126.564 95.489  1.00 86.82  ? 220 PHE R CD1 1 
ATOM 1849 C CD2 . PHE B 2 276 ? 130.602 127.245 94.331  1.00 86.82  ? 220 PHE R CD2 1 
ATOM 1850 C CE1 . PHE B 2 276 ? 128.864 125.261 95.102  1.00 86.82  ? 220 PHE R CE1 1 
ATOM 1851 C CE2 . PHE B 2 276 ? 130.828 125.942 93.942  1.00 86.82  ? 220 PHE R CE2 1 
ATOM 1852 C CZ  . PHE B 2 276 ? 129.958 124.950 94.329  1.00 86.82  ? 220 PHE R CZ  1 
ATOM 1853 N N   . ILE B 2 277 ? 131.864 130.132 96.953  1.00 101.60 ? 221 ILE R N   1 
ATOM 1854 C CA  . ILE B 2 277 ? 133.316 129.982 96.973  1.00 101.60 ? 221 ILE R CA  1 
ATOM 1855 C C   . ILE B 2 277 ? 133.833 129.972 98.405  1.00 101.60 ? 221 ILE R C   1 
ATOM 1856 O O   . ILE B 2 277 ? 134.559 129.059 98.813  1.00 101.60 ? 221 ILE R O   1 
ATOM 1857 C CB  . ILE B 2 277 ? 133.985 131.085 96.136  1.00 86.82  ? 221 ILE R CB  1 
ATOM 1858 C CG1 . ILE B 2 277 ? 133.586 130.943 94.667  1.00 86.82  ? 221 ILE R CG1 1 
ATOM 1859 C CG2 . ILE B 2 277 ? 135.493 131.014 96.279  1.00 86.82  ? 221 ILE R CG2 1 
ATOM 1860 C CD1 . ILE B 2 277 ? 133.841 132.183 93.838  1.00 86.82  ? 221 ILE R CD1 1 
ATOM 1861 N N   . VAL B 2 278 ? 133.478 130.984 99.188  1.00 101.60 ? 222 VAL R N   1 
ATOM 1862 C CA  . VAL B 2 278 ? 133.932 131.072 100.574 1.00 101.60 ? 222 VAL R CA  1 
ATOM 1863 C C   . VAL B 2 278 ? 133.390 129.889 101.370 1.00 101.60 ? 222 VAL R C   1 
ATOM 1864 O O   . VAL B 2 278 ? 134.158 129.226 102.087 1.00 101.60 ? 222 VAL R O   1 
ATOM 1865 C CB  . VAL B 2 278 ? 133.520 132.411 101.205 1.00 86.90  ? 222 VAL R CB  1 
ATOM 1866 C CG1 . VAL B 2 278 ? 133.565 132.329 102.719 1.00 86.90  ? 222 VAL R CG1 1 
ATOM 1867 C CG2 . VAL B 2 278 ? 134.426 133.519 100.707 1.00 86.90  ? 222 VAL R CG2 1 
ATOM 1868 N N   . PRO B 2 279 ? 132.087 129.599 101.307 1.00 101.60 ? 223 PRO R N   1 
ATOM 1869 C CA  . PRO B 2 279 ? 131.574 128.436 102.045 1.00 101.60 ? 223 PRO R CA  1 
ATOM 1870 C C   . PRO B 2 279 ? 132.205 127.130 101.616 1.00 101.60 ? 223 PRO R C   1 
ATOM 1871 O O   . PRO B 2 279 ? 132.524 126.296 102.473 1.00 101.60 ? 223 PRO R O   1 
ATOM 1872 C CB  . PRO B 2 279 ? 130.073 128.462 101.734 1.00 80.90  ? 223 PRO R CB  1 
ATOM 1873 C CG  . PRO B 2 279 ? 129.796 129.865 101.352 1.00 80.90  ? 223 PRO R CG  1 
ATOM 1874 C CD  . PRO B 2 279 ? 131.005 130.311 100.613 1.00 80.90  ? 223 PRO R CD  1 
ATOM 1875 N N   . LEU B 2 280 ? 132.403 126.924 100.313 1.00 101.60 ? 224 LEU R N   1 
ATOM 1876 C CA  . LEU B 2 280 ? 133.032 125.688 99.864  1.00 101.60 ? 224 LEU R CA  1 
ATOM 1877 C C   . LEU B 2 280 ? 134.464 125.590 100.363 1.00 101.60 ? 224 LEU R C   1 
ATOM 1878 O O   . LEU B 2 280 ? 134.906 124.515 100.777 1.00 101.60 ? 224 LEU R O   1 
ATOM 1879 C CB  . LEU B 2 280 ? 132.997 125.591 98.343  1.00 81.74  ? 224 LEU R CB  1 
ATOM 1880 C CG  . LEU B 2 280 ? 133.519 124.260 97.801  1.00 81.74  ? 224 LEU R CG  1 
ATOM 1881 C CD1 . LEU B 2 280 ? 132.549 123.139 98.118  1.00 81.74  ? 224 LEU R CD1 1 
ATOM 1882 C CD2 . LEU B 2 280 ? 133.767 124.355 96.310  1.00 81.74  ? 224 LEU R CD2 1 
ATOM 1883 N N   . LEU B 2 281 ? 135.209 126.693 100.323 1.00 101.60 ? 225 LEU R N   1 
ATOM 1884 C CA  . LEU B 2 281 ? 136.577 126.663 100.823 1.00 101.60 ? 225 LEU R CA  1 
ATOM 1885 C C   . LEU B 2 281 ? 136.607 126.310 102.302 1.00 101.60 ? 225 LEU R C   1 
ATOM 1886 O O   . LEU B 2 281 ? 137.384 125.442 102.725 1.00 101.60 ? 225 LEU R O   1 
ATOM 1887 C CB  . LEU B 2 281 ? 137.251 128.013 100.581 1.00 101.60 ? 225 LEU R CB  1 
ATOM 1888 C CG  . LEU B 2 281 ? 137.667 128.346 99.146  1.00 101.60 ? 225 LEU R CG  1 
ATOM 1889 C CD1 . LEU B 2 281 ? 138.485 129.624 99.124  1.00 101.60 ? 225 LEU R CD1 1 
ATOM 1890 C CD2 . LEU B 2 281 ? 138.448 127.209 98.510  1.00 101.60 ? 225 LEU R CD2 1 
ATOM 1891 N N   . ILE B 2 282 ? 135.762 126.961 103.103 1.00 101.60 ? 226 ILE R N   1 
ATOM 1892 C CA  . ILE B 2 282 ? 135.759 126.690 104.537 1.00 101.60 ? 226 ILE R CA  1 
ATOM 1893 C C   . ILE B 2 282 ? 135.396 125.235 104.799 1.00 101.60 ? 226 ILE R C   1 
ATOM 1894 O O   . ILE B 2 282 ? 136.060 124.544 105.582 1.00 101.60 ? 226 ILE R O   1 
ATOM 1895 C CB  . ILE B 2 282 ? 134.803 127.647 105.269 1.00 76.82  ? 226 ILE R CB  1 
ATOM 1896 C CG1 . ILE B 2 282 ? 135.313 129.083 105.172 1.00 76.82  ? 226 ILE R CG1 1 
ATOM 1897 C CG2 . ILE B 2 282 ? 134.659 127.231 106.722 1.00 76.82  ? 226 ILE R CG2 1 
ATOM 1898 C CD1 . ILE B 2 282 ? 134.352 130.117 105.724 1.00 76.82  ? 226 ILE R CD1 1 
ATOM 1899 N N   . MET B 2 283 ? 134.335 124.746 104.152 1.00 101.60 ? 227 MET R N   1 
ATOM 1900 C CA  . MET B 2 283 ? 133.923 123.368 104.379 1.00 101.60 ? 227 MET R CA  1 
ATOM 1901 C C   . MET B 2 283 ? 135.002 122.389 103.950 1.00 101.60 ? 227 MET R C   1 
ATOM 1902 O O   . MET B 2 283 ? 135.285 121.430 104.674 1.00 101.60 ? 227 MET R O   1 
ATOM 1903 C CB  . MET B 2 283 ? 132.623 123.074 103.638 1.00 76.92  ? 227 MET R CB  1 
ATOM 1904 C CG  . MET B 2 283 ? 131.403 123.694 104.281 1.00 76.92  ? 227 MET R CG  1 
ATOM 1905 S SD  . MET B 2 283 ? 129.933 123.515 103.262 1.00 76.92  ? 227 MET R SD  1 
ATOM 1906 C CE  . MET B 2 283 ? 129.614 121.767 103.462 1.00 76.92  ? 227 MET R CE  1 
ATOM 1907 N N   . LEU B 2 284 ? 135.621 122.609 102.791 1.00 101.60 ? 228 LEU R N   1 
ATOM 1908 C CA  . LEU B 2 284 ? 136.657 121.698 102.328 1.00 101.60 ? 228 LEU R CA  1 
ATOM 1909 C C   . LEU B 2 284 ? 137.815 121.652 103.310 1.00 101.60 ? 228 LEU R C   1 
ATOM 1910 O O   . LEU B 2 284 ? 138.226 120.572 103.740 1.00 101.60 ? 228 LEU R O   1 
ATOM 1911 C CB  . LEU B 2 284 ? 137.145 122.104 100.946 1.00 30.00  ? 228 LEU R CB  1 
ATOM 1912 N N   . PHE B 2 285 ? 138.339 122.815 103.698 1.00 101.60 ? 229 PHE R N   1 
ATOM 1913 C CA  . PHE B 2 285 ? 139.451 122.841 104.643 1.00 101.60 ? 229 PHE R CA  1 
ATOM 1914 C C   . PHE B 2 285 ? 139.086 122.125 105.940 1.00 101.60 ? 229 PHE R C   1 
ATOM 1915 O O   . PHE B 2 285 ? 139.784 121.193 106.378 1.00 101.60 ? 229 PHE R O   1 
ATOM 1916 C CB  . PHE B 2 285 ? 139.842 124.296 104.908 1.00 76.72  ? 229 PHE R CB  1 
ATOM 1917 C CG  . PHE B 2 285 ? 140.855 124.475 105.998 1.00 76.72  ? 229 PHE R CG  1 
ATOM 1918 C CD1 . PHE B 2 285 ? 142.007 123.714 106.031 1.00 76.72  ? 229 PHE R CD1 1 
ATOM 1919 C CD2 . PHE B 2 285 ? 140.657 125.424 106.983 1.00 76.72  ? 229 PHE R CD2 1 
ATOM 1920 C CE1 . PHE B 2 285 ? 142.937 123.891 107.034 1.00 76.72  ? 229 PHE R CE1 1 
ATOM 1921 C CE2 . PHE B 2 285 ? 141.583 125.603 107.986 1.00 76.72  ? 229 PHE R CE2 1 
ATOM 1922 C CZ  . PHE B 2 285 ? 142.724 124.836 108.012 1.00 76.72  ? 229 PHE R CZ  1 
ATOM 1923 N N   . CYS B 2 286 ? 137.966 122.526 106.548 1.00 101.60 ? 230 CYS R N   1 
ATOM 1924 C CA  . CYS B 2 286 ? 137.594 121.997 107.854 1.00 101.60 ? 230 CYS R CA  1 
ATOM 1925 C C   . CYS B 2 286 ? 137.376 120.492 107.801 1.00 101.60 ? 230 CYS R C   1 
ATOM 1926 O O   . CYS B 2 286 ? 137.953 119.740 108.595 1.00 101.60 ? 230 CYS R O   1 
ATOM 1927 C CB  . CYS B 2 286 ? 136.337 122.708 108.348 1.00 75.83  ? 230 CYS R CB  1 
ATOM 1928 S SG  . CYS B 2 286 ? 136.597 124.437 108.782 1.00 75.83  ? 230 CYS R SG  1 
ATOM 1929 N N   . TYR B 2 287 ? 136.544 120.027 106.868 1.00 101.60 ? 231 TYR R N   1 
ATOM 1930 C CA  . TYR B 2 287 ? 136.231 118.610 106.817 1.00 101.60 ? 231 TYR R CA  1 
ATOM 1931 C C   . TYR B 2 287 ? 137.410 117.778 106.341 1.00 101.60 ? 231 TYR R C   1 
ATOM 1932 O O   . TYR B 2 287 ? 137.531 116.625 106.754 1.00 101.60 ? 231 TYR R O   1 
ATOM 1933 C CB  . TYR B 2 287 ? 135.016 118.376 105.925 1.00 75.28  ? 231 TYR R CB  1 
ATOM 1934 C CG  . TYR B 2 287 ? 133.708 118.631 106.636 1.00 75.28  ? 231 TYR R CG  1 
ATOM 1935 C CD1 . TYR B 2 287 ? 133.287 117.810 107.667 1.00 75.28  ? 231 TYR R CD1 1 
ATOM 1936 C CD2 . TYR B 2 287 ? 132.904 119.701 106.287 1.00 75.28  ? 231 TYR R CD2 1 
ATOM 1937 C CE1 . TYR B 2 287 ? 132.100 118.041 108.321 1.00 75.28  ? 231 TYR R CE1 1 
ATOM 1938 C CE2 . TYR B 2 287 ? 131.714 119.940 106.937 1.00 75.28  ? 231 TYR R CE2 1 
ATOM 1939 C CZ  . TYR B 2 287 ? 131.319 119.108 107.953 1.00 75.28  ? 231 TYR R CZ  1 
ATOM 1940 O OH  . TYR B 2 287 ? 130.133 119.343 108.603 1.00 75.28  ? 231 TYR R OH  1 
ATOM 1941 N N   . GLY B 2 288 ? 138.297 118.324 105.516 1.00 101.60 ? 232 GLY R N   1 
ATOM 1942 C CA  . GLY B 2 288 ? 139.483 117.588 105.142 1.00 101.60 ? 232 GLY R CA  1 
ATOM 1943 C C   . GLY B 2 288 ? 140.371 117.324 106.337 1.00 101.60 ? 232 GLY R C   1 
ATOM 1944 O O   . GLY B 2 288 ? 140.826 116.192 106.543 1.00 101.60 ? 232 GLY R O   1 
ATOM 1945 N N   . PHE B 2 289 ? 140.617 118.351 107.152 1.00 101.60 ? 233 PHE R N   1 
ATOM 1946 C CA  . PHE B 2 289 ? 141.459 118.110 108.321 1.00 101.60 ? 233 PHE R CA  1 
ATOM 1947 C C   . PHE B 2 289 ? 140.749 117.249 109.360 1.00 101.60 ? 233 PHE R C   1 
ATOM 1948 O O   . PHE B 2 289 ? 141.394 116.435 110.037 1.00 101.60 ? 233 PHE R O   1 
ATOM 1949 C CB  . PHE B 2 289 ? 141.929 119.432 108.915 1.00 76.36  ? 233 PHE R CB  1 
ATOM 1950 C CG  . PHE B 2 289 ? 143.134 119.991 108.224 1.00 76.36  ? 233 PHE R CG  1 
ATOM 1951 C CD1 . PHE B 2 289 ? 143.060 120.415 106.911 1.00 76.36  ? 233 PHE R CD1 1 
ATOM 1952 C CD2 . PHE B 2 289 ? 144.349 120.066 108.878 1.00 76.36  ? 233 PHE R CD2 1 
ATOM 1953 C CE1 . PHE B 2 289 ? 144.170 120.919 106.268 1.00 76.36  ? 233 PHE R CE1 1 
ATOM 1954 C CE2 . PHE B 2 289 ? 145.462 120.570 108.240 1.00 76.36  ? 233 PHE R CE2 1 
ATOM 1955 C CZ  . PHE B 2 289 ? 145.372 120.996 106.933 1.00 76.36  ? 233 PHE R CZ  1 
ATOM 1956 N N   . THR B 2 290 ? 139.427 117.385 109.486 1.00 101.60 ? 234 THR R N   1 
ATOM 1957 C CA  . THR B 2 290 ? 138.687 116.478 110.355 1.00 101.60 ? 234 THR R CA  1 
ATOM 1958 C C   . THR B 2 290 ? 138.829 115.037 109.891 1.00 101.60 ? 234 THR R C   1 
ATOM 1959 O O   . THR B 2 290 ? 139.015 114.132 110.714 1.00 101.60 ? 234 THR R O   1 
ATOM 1960 C CB  . THR B 2 290 ? 137.214 116.872 110.397 1.00 75.32  ? 234 THR R CB  1 
ATOM 1961 O OG1 . THR B 2 290 ? 137.078 118.156 111.013 1.00 75.32  ? 234 THR R OG1 1 
ATOM 1962 C CG2 . THR B 2 290 ? 136.413 115.853 111.180 1.00 75.32  ? 234 THR R CG2 1 
ATOM 1963 N N   . LEU B 2 291 ? 138.741 114.804 108.582 1.00 101.60 ? 235 LEU R N   1 
ATOM 1964 C CA  . LEU B 2 291 ? 138.928 113.468 108.039 1.00 101.60 ? 235 LEU R CA  1 
ATOM 1965 C C   . LEU B 2 291 ? 140.327 112.949 108.309 1.00 101.60 ? 235 LEU R C   1 
ATOM 1966 O O   . LEU B 2 291 ? 140.488 111.775 108.642 1.00 101.60 ? 235 LEU R O   1 
ATOM 1967 C CB  . LEU B 2 291 ? 138.656 113.468 106.537 1.00 79.10  ? 235 LEU R CB  1 
ATOM 1968 C CG  . LEU B 2 291 ? 137.185 113.361 106.144 1.00 79.10  ? 235 LEU R CG  1 
ATOM 1969 C CD1 . LEU B 2 291 ? 136.995 113.742 104.688 1.00 79.10  ? 235 LEU R CD1 1 
ATOM 1970 C CD2 . LEU B 2 291 ? 136.670 111.961 106.407 1.00 79.10  ? 235 LEU R CD2 1 
ATOM 1971 N N   . ARG B 2 292 ? 141.344 113.796 108.168 1.00 101.60 ? 236 ARG R N   1 
ATOM 1972 C CA  . ARG B 2 292 ? 142.695 113.356 108.499 1.00 101.60 ? 236 ARG R CA  1 
ATOM 1973 C C   . ARG B 2 292 ? 142.779 112.899 109.950 1.00 101.60 ? 236 ARG R C   1 
ATOM 1974 O O   . ARG B 2 292 ? 143.230 111.780 110.238 1.00 101.60 ? 236 ARG R O   1 
ATOM 1975 C CB  . ARG B 2 292 ? 143.695 114.480 108.239 1.00 81.49  ? 236 ARG R CB  1 
ATOM 1976 C CG  . ARG B 2 292 ? 145.069 114.221 108.834 1.00 81.49  ? 236 ARG R CG  1 
ATOM 1977 C CD  . ARG B 2 292 ? 146.161 114.965 108.084 1.00 81.49  ? 236 ARG R CD  1 
ATOM 1978 N NE  . ARG B 2 292 ? 146.270 114.532 106.696 1.00 81.49  ? 236 ARG R NE  1 
ATOM 1979 C CZ  . ARG B 2 292 ? 147.184 114.972 105.842 1.00 81.49  ? 236 ARG R CZ  1 
ATOM 1980 N NH1 . ARG B 2 292 ? 148.095 115.863 106.201 1.00 81.49  ? 236 ARG R NH1 1 
ATOM 1981 N NH2 . ARG B 2 292 ? 147.186 114.507 104.597 1.00 81.49  ? 236 ARG R NH2 1 
ATOM 1982 N N   . THR B 2 293 ? 142.327 113.743 110.879 1.00 101.60 ? 237 THR R N   1 
ATOM 1983 C CA  . THR B 2 293 ? 142.441 113.391 112.291 1.00 101.60 ? 237 THR R CA  1 
ATOM 1984 C C   . THR B 2 293 ? 141.658 112.126 112.617 1.00 101.60 ? 237 THR R C   1 
ATOM 1985 O O   . THR B 2 293 ? 142.150 111.269 113.358 1.00 101.60 ? 237 THR R O   1 
ATOM 1986 C CB  . THR B 2 293 ? 141.969 114.543 113.170 1.00 80.30  ? 237 THR R CB  1 
ATOM 1987 O OG1 . THR B 2 293 ? 140.760 115.089 112.633 1.00 80.30  ? 237 THR R OG1 1 
ATOM 1988 C CG2 . THR B 2 293 ? 143.033 115.625 113.241 1.00 80.30  ? 237 THR R CG2 1 
ATOM 1989 N N   . LEU B 2 294 ? 140.446 111.980 112.079 1.00 101.60 ? 238 LEU R N   1 
ATOM 1990 C CA  . LEU B 2 294 ? 139.717 110.735 112.285 1.00 101.60 ? 238 LEU R CA  1 
ATOM 1991 C C   . LEU B 2 294 ? 140.446 109.539 111.693 1.00 101.60 ? 238 LEU R C   1 
ATOM 1992 O O   . LEU B 2 294 ? 140.500 108.487 112.335 1.00 101.60 ? 238 LEU R O   1 
ATOM 1993 C CB  . LEU B 2 294 ? 138.318 110.821 111.677 1.00 78.03  ? 238 LEU R CB  1 
ATOM 1994 C CG  . LEU B 2 294 ? 137.349 111.790 112.349 1.00 78.03  ? 238 LEU R CG  1 
ATOM 1995 C CD1 . LEU B 2 294 ? 136.363 112.329 111.334 1.00 78.03  ? 238 LEU R CD1 1 
ATOM 1996 C CD2 . LEU B 2 294 ? 136.626 111.122 113.495 1.00 78.03  ? 238 LEU R CD2 1 
ATOM 1997 N N   . PHE B 2 295 ? 141.014 109.677 110.497 1.00 101.60 ? 239 PHE R N   1 
ATOM 1998 C CA  . PHE B 2 295 ? 141.752 108.591 109.877 1.00 101.60 ? 239 PHE R CA  1 
ATOM 1999 C C   . PHE B 2 295 ? 142.955 108.178 110.704 1.00 101.60 ? 239 PHE R C   1 
ATOM 2000 O O   . PHE B 2 295 ? 143.370 107.017 110.629 1.00 101.60 ? 239 PHE R O   1 
ATOM 2001 C CB  . PHE B 2 295 ? 142.200 109.005 108.475 1.00 86.35  ? 239 PHE R CB  1 
ATOM 2002 C CG  . PHE B 2 295 ? 142.743 107.875 107.649 1.00 86.35  ? 239 PHE R CG  1 
ATOM 2003 C CD1 . PHE B 2 295 ? 144.058 107.467 107.784 1.00 86.35  ? 239 PHE R CD1 1 
ATOM 2004 C CD2 . PHE B 2 295 ? 141.937 107.227 106.731 1.00 86.35  ? 239 PHE R CD2 1 
ATOM 2005 C CE1 . PHE B 2 295 ? 144.555 106.430 107.022 1.00 86.35  ? 239 PHE R CE1 1 
ATOM 2006 C CE2 . PHE B 2 295 ? 142.430 106.190 105.967 1.00 86.35  ? 239 PHE R CE2 1 
ATOM 2007 C CZ  . PHE B 2 295 ? 143.741 105.792 106.113 1.00 86.35  ? 239 PHE R CZ  1 
ATOM 2008 N N   . LYS B 2 296 ? 143.518 109.092 111.493 1.00 91.61  ? 240 LYS R N   1 
ATOM 2009 C CA  . LYS B 2 296 ? 144.589 108.738 112.414 1.00 91.61  ? 240 LYS R CA  1 
ATOM 2010 C C   . LYS B 2 296 ? 144.072 108.354 113.797 1.00 91.61  ? 240 LYS R C   1 
ATOM 2011 O O   . LYS B 2 296 ? 144.767 108.585 114.792 1.00 91.61  ? 240 LYS R O   1 
ATOM 2012 C CB  . LYS B 2 296 ? 145.579 109.887 112.527 1.00 30.00  ? 240 LYS R CB  1 
ATOM 2013 N N   . ALA B 2 297 ? 142.877 107.777 113.885 1.00 86.54  ? 241 ALA R N   1 
ATOM 2014 C CA  . ALA B 2 297 ? 142.276 107.418 115.161 1.00 86.54  ? 241 ALA R CA  1 
ATOM 2015 C C   . ALA B 2 297 ? 142.057 105.914 115.260 1.00 86.54  ? 241 ALA R C   1 
ATOM 2016 O O   . ALA B 2 297 ? 141.846 105.222 114.262 1.00 86.54  ? 241 ALA R O   1 
ATOM 2017 C CB  . ALA B 2 297 ? 140.944 108.147 115.354 1.00 86.54  ? 241 ALA R CB  1 
ATOM 2018 N N   . HIS B 2 298 ? 142.113 105.414 116.494 1.00 87.38  ? 242 HIS R N   1 
ATOM 2019 C CA  . HIS B 2 298 ? 141.832 104.019 116.802 1.00 87.38  ? 242 HIS R CA  1 
ATOM 2020 C C   . HIS B 2 298 ? 140.478 103.832 117.474 1.00 87.38  ? 242 HIS R C   1 
ATOM 2021 O O   . HIS B 2 298 ? 140.276 102.836 118.175 1.00 87.38  ? 242 HIS R O   1 
ATOM 2022 C CB  . HIS B 2 298 ? 142.938 103.444 117.686 1.00 87.38  ? 242 HIS R CB  1 
ATOM 2023 C CG  . HIS B 2 298 ? 144.264 103.346 116.999 1.00 87.38  ? 242 HIS R CG  1 
ATOM 2024 N ND1 . HIS B 2 298 ? 144.411 102.801 115.742 1.00 87.38  ? 242 HIS R ND1 1 
ATOM 2025 C CD2 . HIS B 2 298 ? 145.503 103.727 117.391 1.00 87.38  ? 242 HIS R CD2 1 
ATOM 2026 C CE1 . HIS B 2 298 ? 145.683 102.846 115.390 1.00 87.38  ? 242 HIS R CE1 1 
ATOM 2027 N NE2 . HIS B 2 298 ? 146.367 103.404 116.373 1.00 87.38  ? 242 HIS R NE2 1 
ATOM 2028 N N   . MET B 2 299 ? 139.551 104.762 117.274 1.00 88.55  ? 243 MET R N   1 
ATOM 2029 C CA  . MET B 2 299 ? 138.244 104.675 117.908 1.00 88.55  ? 243 MET R CA  1 
ATOM 2030 C C   . MET B 2 299 ? 137.484 103.456 117.404 1.00 88.55  ? 243 MET R C   1 
ATOM 2031 O O   . MET B 2 299 ? 137.932 102.742 116.504 1.00 88.55  ? 243 MET R O   1 
ATOM 2032 C CB  . MET B 2 299 ? 137.434 105.937 117.624 1.00 88.55  ? 243 MET R CB  1 
ATOM 2033 C CG  . MET B 2 299 ? 138.066 107.207 118.177 1.00 88.55  ? 243 MET R CG  1 
ATOM 2034 S SD  . MET B 2 299 ? 137.497 108.761 117.452 1.00 88.55  ? 243 MET R SD  1 
ATOM 2035 C CE  . MET B 2 299 ? 137.130 108.300 115.763 1.00 88.55  ? 243 MET R CE  1 
ATOM 2036 N N   . GLY B 2 300 ? 136.318 103.216 118.007 1.00 89.70  ? 244 GLY R N   1 
ATOM 2037 C CA  . GLY B 2 300 ? 135.484 102.109 117.575 1.00 89.70  ? 244 GLY R CA  1 
ATOM 2038 C C   . GLY B 2 300 ? 134.458 102.495 116.528 1.00 89.70  ? 244 GLY R C   1 
ATOM 2039 O O   . GLY B 2 300 ? 133.872 101.622 115.881 1.00 89.70  ? 244 GLY R O   1 
ATOM 2040 N N   . GLN B 2 301 ? 134.218 103.795 116.347 1.00 101.60 ? 245 GLN R N   1 
ATOM 2041 C CA  . GLN B 2 301 ? 133.186 104.282 115.440 1.00 101.60 ? 245 GLN R CA  1 
ATOM 2042 C C   . GLN B 2 301 ? 133.715 105.362 114.501 1.00 101.60 ? 245 GLN R C   1 
ATOM 2043 O O   . GLN B 2 301 ? 133.057 106.379 114.281 1.00 101.60 ? 245 GLN R O   1 
ATOM 2044 C CB  . GLN B 2 301 ? 131.985 104.805 116.226 1.00 101.60 ? 245 GLN R CB  1 
ATOM 2045 C CG  . GLN B 2 301 ? 131.687 104.030 117.496 1.00 101.60 ? 245 GLN R CG  1 
ATOM 2046 C CD  . GLN B 2 301 ? 132.316 104.659 118.720 1.00 101.60 ? 245 GLN R CD  1 
ATOM 2047 O OE1 . GLN B 2 301 ? 132.108 105.839 119.001 1.00 101.60 ? 245 GLN R OE1 1 
ATOM 2048 N NE2 . GLN B 2 301 ? 133.097 103.876 119.453 1.00 101.60 ? 245 GLN R NE2 1 
ATOM 2049 N N   . LYS B 2 302 ? 134.908 105.158 113.944 1.00 101.60 ? 246 LYS R N   1 
ATOM 2050 C CA  . LYS B 2 302 ? 135.407 106.070 112.921 1.00 101.60 ? 246 LYS R CA  1 
ATOM 2051 C C   . LYS B 2 302 ? 134.596 105.961 111.636 1.00 101.60 ? 246 LYS R C   1 
ATOM 2052 O O   . LYS B 2 302 ? 134.397 106.962 110.931 1.00 101.60 ? 246 LYS R O   1 
ATOM 2053 C CB  . LYS B 2 302 ? 136.878 105.770 112.633 1.00 85.64  ? 246 LYS R CB  1 
ATOM 2054 C CG  . LYS B 2 302 ? 137.125 104.341 112.150 1.00 85.64  ? 246 LYS R CG  1 
ATOM 2055 C CD  . LYS B 2 302 ? 138.592 103.929 112.219 1.00 85.64  ? 246 LYS R CD  1 
ATOM 2056 C CE  . LYS B 2 302 ? 139.537 105.083 111.940 1.00 85.64  ? 246 LYS R CE  1 
ATOM 2057 N NZ  . LYS B 2 302 ? 140.917 104.604 111.656 1.00 85.64  ? 246 LYS R NZ  1 
ATOM 2058 N N   . HIS B 2 303 ? 134.115 104.757 111.325 1.00 101.60 ? 247 HIS R N   1 
ATOM 2059 C CA  . HIS B 2 303 ? 133.542 104.490 110.012 1.00 101.60 ? 247 HIS R CA  1 
ATOM 2060 C C   . HIS B 2 303 ? 132.331 105.376 109.756 1.00 101.60 ? 247 HIS R C   1 
ATOM 2061 O O   . HIS B 2 303 ? 132.246 106.059 108.728 1.00 101.60 ? 247 HIS R O   1 
ATOM 2062 C CB  . HIS B 2 303 ? 133.157 103.012 109.905 1.00 101.60 ? 247 HIS R CB  1 
ATOM 2063 C CG  . HIS B 2 303 ? 134.302 102.064 110.099 1.00 101.60 ? 247 HIS R CG  1 
ATOM 2064 N ND1 . HIS B 2 303 ? 135.069 102.037 111.244 1.00 101.60 ? 247 HIS R ND1 1 
ATOM 2065 C CD2 . HIS B 2 303 ? 134.806 101.103 109.289 1.00 101.60 ? 247 HIS R CD2 1 
ATOM 2066 C CE1 . HIS B 2 303 ? 135.995 101.103 111.131 1.00 101.60 ? 247 HIS R CE1 1 
ATOM 2067 N NE2 . HIS B 2 303 ? 135.858 100.521 109.954 1.00 101.60 ? 247 HIS R NE2 1 
ATOM 2068 N N   . ARG B 2 304 ? 131.378 105.374 110.688 1.00 101.60 ? 248 ARG R N   1 
ATOM 2069 C CA  . ARG B 2 304 ? 130.149 106.127 110.482 1.00 101.60 ? 248 ARG R CA  1 
ATOM 2070 C C   . ARG B 2 304 ? 130.422 107.620 110.404 1.00 101.60 ? 248 ARG R C   1 
ATOM 2071 O O   . ARG B 2 304 ? 129.799 108.322 109.602 1.00 101.60 ? 248 ARG R O   1 
ATOM 2072 C CB  . ARG B 2 304 ? 129.155 105.821 111.599 1.00 101.60 ? 248 ARG R CB  1 
ATOM 2073 C CG  . ARG B 2 304 ? 127.746 106.327 111.330 1.00 101.60 ? 248 ARG R CG  1 
ATOM 2074 C CD  . ARG B 2 304 ? 126.706 105.341 111.839 1.00 101.60 ? 248 ARG R CD  1 
ATOM 2075 N NE  . ARG B 2 304 ? 125.389 105.574 111.258 1.00 101.60 ? 248 ARG R NE  1 
ATOM 2076 C CZ  . ARG B 2 304 ? 124.239 105.351 111.881 1.00 101.60 ? 248 ARG R CZ  1 
ATOM 2077 N NH1 . ARG B 2 304 ? 124.198 104.866 113.112 1.00 101.60 ? 248 ARG R NH1 1 
ATOM 2078 N NH2 . ARG B 2 304 ? 123.099 105.612 111.248 1.00 101.60 ? 248 ARG R NH2 1 
ATOM 2079 N N   . ALA B 2 305 ? 131.338 108.127 111.229 1.00 101.60 ? 249 ALA R N   1 
ATOM 2080 C CA  . ALA B 2 305 ? 131.668 109.544 111.158 1.00 101.60 ? 249 ALA R CA  1 
ATOM 2081 C C   . ALA B 2 305 ? 132.240 109.913 109.797 1.00 101.60 ? 249 ALA R C   1 
ATOM 2082 O O   . ALA B 2 305 ? 131.838 110.928 109.211 1.00 101.60 ? 249 ALA R O   1 
ATOM 2083 C CB  . ALA B 2 305 ? 132.653 109.908 112.265 1.00 83.91  ? 249 ALA R CB  1 
ATOM 2084 N N   . MET B 2 306 ? 133.168 109.109 109.274 1.00 101.60 ? 250 MET R N   1 
ATOM 2085 C CA  . MET B 2 306 ? 133.702 109.406 107.950 1.00 101.60 ? 250 MET R CA  1 
ATOM 2086 C C   . MET B 2 306 ? 132.607 109.363 106.892 1.00 101.60 ? 250 MET R C   1 
ATOM 2087 O O   . MET B 2 306 ? 132.546 110.245 106.022 1.00 101.60 ? 250 MET R O   1 
ATOM 2088 C CB  . MET B 2 306 ? 134.818 108.423 107.599 1.00 101.60 ? 250 MET R CB  1 
ATOM 2089 C CG  . MET B 2 306 ? 135.987 108.449 108.567 1.00 101.60 ? 250 MET R CG  1 
ATOM 2090 S SD  . MET B 2 306 ? 137.055 107.010 108.408 1.00 101.60 ? 250 MET R SD  1 
ATOM 2091 C CE  . MET B 2 306 ? 138.570 107.780 107.854 1.00 101.60 ? 250 MET R CE  1 
ATOM 2092 N N   . ARG B 2 307 ? 131.730 108.360 106.957 1.00 101.60 ? 251 ARG R N   1 
ATOM 2093 C CA  . ARG B 2 307 ? 130.653 108.271 105.978 1.00 101.60 ? 251 ARG R CA  1 
ATOM 2094 C C   . ARG B 2 307 ? 129.762 109.503 106.036 1.00 101.60 ? 251 ARG R C   1 
ATOM 2095 O O   . ARG B 2 307 ? 129.396 110.060 104.998 1.00 101.60 ? 251 ARG R O   1 
ATOM 2096 C CB  . ARG B 2 307 ? 129.822 107.008 106.205 1.00 101.60 ? 251 ARG R CB  1 
ATOM 2097 C CG  . ARG B 2 307 ? 130.592 105.710 106.072 1.00 101.60 ? 251 ARG R CG  1 
ATOM 2098 C CD  . ARG B 2 307 ? 129.700 104.604 105.537 1.00 101.60 ? 251 ARG R CD  1 
ATOM 2099 N NE  . ARG B 2 307 ? 130.214 103.277 105.853 1.00 101.60 ? 251 ARG R NE  1 
ATOM 2100 C CZ  . ARG B 2 307 ? 131.355 102.781 105.393 1.00 101.60 ? 251 ARG R CZ  1 
ATOM 2101 N NH1 . ARG B 2 307 ? 132.132 103.473 104.575 1.00 101.60 ? 251 ARG R NH1 1 
ATOM 2102 N NH2 . ARG B 2 307 ? 131.725 101.558 105.761 1.00 101.60 ? 251 ARG R NH2 1 
ATOM 2103 N N   . VAL B 2 308 ? 129.405 109.947 107.241 1.00 101.60 ? 252 VAL R N   1 
ATOM 2104 C CA  . VAL B 2 308 ? 128.497 111.082 107.364 1.00 101.60 ? 252 VAL R CA  1 
ATOM 2105 C C   . VAL B 2 308 ? 129.160 112.359 106.867 1.00 101.60 ? 252 VAL R C   1 
ATOM 2106 O O   . VAL B 2 308 ? 128.516 113.194 106.223 1.00 101.60 ? 252 VAL R O   1 
ATOM 2107 C CB  . VAL B 2 308 ? 128.009 111.227 108.814 1.00 101.60 ? 252 VAL R CB  1 
ATOM 2108 C CG1 . VAL B 2 308 ? 127.251 112.526 108.984 1.00 101.60 ? 252 VAL R CG1 1 
ATOM 2109 C CG2 . VAL B 2 308 ? 127.127 110.054 109.186 1.00 101.60 ? 252 VAL R CG2 1 
ATOM 2110 N N   . ILE B 2 309 ? 130.448 112.547 107.164 1.00 101.60 ? 253 ILE R N   1 
ATOM 2111 C CA  . ILE B 2 309 ? 131.128 113.748 106.682 1.00 101.60 ? 253 ILE R CA  1 
ATOM 2112 C C   . ILE B 2 309 ? 131.159 113.763 105.158 1.00 101.60 ? 253 ILE R C   1 
ATOM 2113 O O   . ILE B 2 309 ? 130.849 114.784 104.520 1.00 101.60 ? 253 ILE R O   1 
ATOM 2114 C CB  . ILE B 2 309 ? 132.542 113.839 107.281 1.00 101.60 ? 253 ILE R CB  1 
ATOM 2115 C CG1 . ILE B 2 309 ? 132.463 114.331 108.725 1.00 101.60 ? 253 ILE R CG1 1 
ATOM 2116 C CG2 . ILE B 2 309 ? 133.408 114.762 106.448 1.00 101.60 ? 253 ILE R CG2 1 
ATOM 2117 C CD1 . ILE B 2 309 ? 133.748 114.175 109.496 1.00 101.60 ? 253 ILE R CD1 1 
ATOM 2118 N N   . PHE B 2 310 ? 131.527 112.634 104.547 1.00 101.60 ? 254 PHE R N   1 
ATOM 2119 C CA  . PHE B 2 310 ? 131.523 112.581 103.090 1.00 101.60 ? 254 PHE R CA  1 
ATOM 2120 C C   . PHE B 2 310 ? 130.127 112.805 102.534 1.00 101.60 ? 254 PHE R C   1 
ATOM 2121 O O   . PHE B 2 310 ? 129.970 113.473 101.506 1.00 101.60 ? 254 PHE R O   1 
ATOM 2122 C CB  . PHE B 2 310 ? 132.077 111.244 102.596 1.00 101.60 ? 254 PHE R CB  1 
ATOM 2123 C CG  . PHE B 2 310 ? 133.522 111.297 102.184 1.00 101.60 ? 254 PHE R CG  1 
ATOM 2124 C CD1 . PHE B 2 310 ? 133.988 112.306 101.357 1.00 101.60 ? 254 PHE R CD1 1 
ATOM 2125 C CD2 . PHE B 2 310 ? 134.414 110.333 102.621 1.00 101.60 ? 254 PHE R CD2 1 
ATOM 2126 C CE1 . PHE B 2 310 ? 135.312 112.355 100.980 1.00 101.60 ? 254 PHE R CE1 1 
ATOM 2127 C CE2 . PHE B 2 310 ? 135.741 110.377 102.245 1.00 101.60 ? 254 PHE R CE2 1 
ATOM 2128 C CZ  . PHE B 2 310 ? 136.190 111.390 101.423 1.00 101.60 ? 254 PHE R CZ  1 
ATOM 2129 N N   . ALA B 2 311 ? 129.106 112.256 103.190 1.00 101.60 ? 255 ALA R N   1 
ATOM 2130 C CA  . ALA B 2 311 ? 127.740 112.457 102.730 1.00 101.60 ? 255 ALA R CA  1 
ATOM 2131 C C   . ALA B 2 311 ? 127.375 113.932 102.754 1.00 101.60 ? 255 ALA R C   1 
ATOM 2132 O O   . ALA B 2 311 ? 126.784 114.449 101.805 1.00 101.60 ? 255 ALA R O   1 
ATOM 2133 C CB  . ALA B 2 311 ? 126.772 111.649 103.593 1.00 101.60 ? 255 ALA R CB  1 
ATOM 2134 N N   . VAL B 2 312 ? 127.728 114.630 103.832 1.00 101.60 ? 256 VAL R N   1 
ATOM 2135 C CA  . VAL B 2 312 ? 127.393 116.047 103.923 1.00 101.60 ? 256 VAL R CA  1 
ATOM 2136 C C   . VAL B 2 312 ? 128.062 116.819 102.796 1.00 101.60 ? 256 VAL R C   1 
ATOM 2137 O O   . VAL B 2 312 ? 127.422 117.625 102.107 1.00 101.60 ? 256 VAL R O   1 
ATOM 2138 C CB  . VAL B 2 312 ? 127.794 116.606 105.298 1.00 101.60 ? 256 VAL R CB  1 
ATOM 2139 C CG1 . VAL B 2 312 ? 127.752 118.122 105.279 1.00 101.60 ? 256 VAL R CG1 1 
ATOM 2140 C CG2 . VAL B 2 312 ? 126.883 116.062 106.376 1.00 101.60 ? 256 VAL R CG2 1 
ATOM 2141 N N   . VAL B 2 313 ? 129.357 116.581 102.581 1.00 101.60 ? 257 VAL R N   1 
ATOM 2142 C CA  . VAL B 2 313 ? 130.063 117.350 101.558 1.00 101.60 ? 257 VAL R CA  1 
ATOM 2143 C C   . VAL B 2 313 ? 129.496 117.052 100.173 1.00 101.60 ? 257 VAL R C   1 
ATOM 2144 O O   . VAL B 2 313 ? 129.235 117.969 99.379  1.00 101.60 ? 257 VAL R O   1 
ATOM 2145 C CB  . VAL B 2 313 ? 131.573 117.074 101.623 1.00 101.60 ? 257 VAL R CB  1 
ATOM 2146 C CG1 . VAL B 2 313 ? 132.297 117.878 100.562 1.00 101.60 ? 257 VAL R CG1 1 
ATOM 2147 C CG2 . VAL B 2 313 ? 132.110 117.418 102.994 1.00 101.60 ? 257 VAL R CG2 1 
ATOM 2148 N N   . LEU B 2 314 ? 129.296 115.770 99.857  1.00 101.60 ? 258 LEU R N   1 
ATOM 2149 C CA  . LEU B 2 314 ? 128.792 115.414 98.536  1.00 101.60 ? 258 LEU R CA  1 
ATOM 2150 C C   . LEU B 2 314 ? 127.377 115.931 98.325  1.00 101.60 ? 258 LEU R C   1 
ATOM 2151 O O   . LEU B 2 314 ? 127.029 116.348 97.218  1.00 101.60 ? 258 LEU R O   1 
ATOM 2152 C CB  . LEU B 2 314 ? 128.842 113.901 98.338  1.00 101.60 ? 258 LEU R CB  1 
ATOM 2153 C CG  . LEU B 2 314 ? 130.244 113.296 98.316  1.00 101.60 ? 258 LEU R CG  1 
ATOM 2154 C CD1 . LEU B 2 314 ? 130.169 111.779 98.360  1.00 101.60 ? 258 LEU R CD1 1 
ATOM 2155 C CD2 . LEU B 2 314 ? 131.010 113.766 97.090  1.00 101.60 ? 258 LEU R CD2 1 
ATOM 2156 N N   . ILE B 2 315 ? 126.540 115.900 99.363  1.00 101.60 ? 259 ILE R N   1 
ATOM 2157 C CA  . ILE B 2 315 ? 125.188 116.425 99.228  1.00 101.60 ? 259 ILE R CA  1 
ATOM 2158 C C   . ILE B 2 315 ? 125.226 117.919 98.961  1.00 101.60 ? 259 ILE R C   1 
ATOM 2159 O O   . ILE B 2 315 ? 124.503 118.418 98.092  1.00 101.60 ? 259 ILE R O   1 
ATOM 2160 C CB  . ILE B 2 315 ? 124.359 116.097 100.484 1.00 101.60 ? 259 ILE R CB  1 
ATOM 2161 C CG1 . ILE B 2 315 ? 124.091 114.594 100.570 1.00 101.60 ? 259 ILE R CG1 1 
ATOM 2162 C CG2 . ILE B 2 315 ? 123.049 116.868 100.473 1.00 101.60 ? 259 ILE R CG2 1 
ATOM 2163 C CD1 . ILE B 2 315 ? 123.047 114.093 99.603  1.00 101.60 ? 259 ILE R CD1 1 
ATOM 2164 N N   . PHE B 2 316 ? 126.065 118.660 99.688  1.00 101.60 ? 260 PHE R N   1 
ATOM 2165 C CA  . PHE B 2 316 ? 126.157 120.095 99.436  1.00 101.60 ? 260 PHE R CA  1 
ATOM 2166 C C   . PHE B 2 316 ? 126.582 120.370 98.001  1.00 101.60 ? 260 PHE R C   1 
ATOM 2167 O O   . PHE B 2 316 ? 125.989 121.221 97.319  1.00 101.60 ? 260 PHE R O   1 
ATOM 2168 C CB  . PHE B 2 316 ? 127.135 120.740 100.415 1.00 101.60 ? 260 PHE R CB  1 
ATOM 2169 C CG  . PHE B 2 316 ? 127.400 122.191 100.140 1.00 101.60 ? 260 PHE R CG  1 
ATOM 2170 C CD1 . PHE B 2 316 ? 128.369 122.574 99.233  1.00 101.60 ? 260 PHE R CD1 1 
ATOM 2171 C CD2 . PHE B 2 316 ? 126.680 123.172 100.791 1.00 101.60 ? 260 PHE R CD2 1 
ATOM 2172 C CE1 . PHE B 2 316 ? 128.610 123.904 98.983  1.00 101.60 ? 260 PHE R CE1 1 
ATOM 2173 C CE2 . PHE B 2 316 ? 126.920 124.504 100.542 1.00 101.60 ? 260 PHE R CE2 1 
ATOM 2174 C CZ  . PHE B 2 316 ? 127.885 124.869 99.638  1.00 101.60 ? 260 PHE R CZ  1 
ATOM 2175 N N   . LEU B 2 317 ? 127.611 119.668 97.525  1.00 101.60 ? 261 LEU R N   1 
ATOM 2176 C CA  . LEU B 2 317 ? 128.053 119.886 96.152  1.00 101.60 ? 261 LEU R CA  1 
ATOM 2177 C C   . LEU B 2 317 ? 126.949 119.537 95.162  1.00 101.60 ? 261 LEU R C   1 
ATOM 2178 O O   . LEU B 2 317 ? 126.575 120.357 94.320  1.00 101.60 ? 261 LEU R O   1 
ATOM 2179 C CB  . LEU B 2 317 ? 129.318 119.077 95.866  1.00 101.60 ? 261 LEU R CB  1 
ATOM 2180 C CG  . LEU B 2 317 ? 130.633 119.699 96.342  1.00 101.60 ? 261 LEU R CG  1 
ATOM 2181 C CD1 . LEU B 2 317 ? 131.802 118.804 95.973  1.00 101.60 ? 261 LEU R CD1 1 
ATOM 2182 C CD2 . LEU B 2 317 ? 130.829 121.088 95.756  1.00 101.60 ? 261 LEU R CD2 1 
ATOM 2183 N N   . LEU B 2 318 ? 126.386 118.332 95.271  1.00 101.60 ? 262 LEU R N   1 
ATOM 2184 C CA  . LEU B 2 318 ? 125.324 117.928 94.358  1.00 101.60 ? 262 LEU R CA  1 
ATOM 2185 C C   . LEU B 2 318 ? 124.180 118.927 94.363  1.00 101.60 ? 262 LEU R C   1 
ATOM 2186 O O   . LEU B 2 318 ? 123.528 119.132 93.333  1.00 101.60 ? 262 LEU R O   1 
ATOM 2187 C CB  . LEU B 2 318 ? 124.810 116.539 94.738  1.00 101.60 ? 262 LEU R CB  1 
ATOM 2188 C CG  . LEU B 2 318 ? 123.541 116.041 94.043  1.00 101.60 ? 262 LEU R CG  1 
ATOM 2189 C CD1 . LEU B 2 318 ? 123.875 115.466 92.682  1.00 101.60 ? 262 LEU R CD1 1 
ATOM 2190 C CD2 . LEU B 2 318 ? 122.837 115.010 94.903  1.00 101.60 ? 262 LEU R CD2 1 
ATOM 2191 N N   . CYS B 2 319 ? 123.913 119.552 95.506  1.00 101.60 ? 263 CYS R N   1 
ATOM 2192 C CA  . CYS B 2 319 ? 122.814 120.497 95.608  1.00 101.60 ? 263 CYS R CA  1 
ATOM 2193 C C   . CYS B 2 319 ? 123.112 121.835 94.952  1.00 101.60 ? 263 CYS R C   1 
ATOM 2194 O O   . CYS B 2 319 ? 122.236 122.383 94.275  1.00 101.60 ? 263 CYS R O   1 
ATOM 2195 C CB  . CYS B 2 319 ? 122.456 120.730 97.078  1.00 101.60 ? 263 CYS R CB  1 
ATOM 2196 S SG  . CYS B 2 319 ? 121.433 119.431 97.805  1.00 101.60 ? 263 CYS R SG  1 
ATOM 2197 N N   . TRP B 2 320 ? 124.320 122.379 95.124  1.00 101.60 ? 264 TRP R N   1 
ATOM 2198 C CA  . TRP B 2 320 ? 124.563 123.761 94.728  1.00 101.60 ? 264 TRP R CA  1 
ATOM 2199 C C   . TRP B 2 320 ? 125.500 123.955 93.544  1.00 101.60 ? 264 TRP R C   1 
ATOM 2200 O O   . TRP B 2 320 ? 125.528 125.060 92.993  1.00 101.60 ? 264 TRP R O   1 
ATOM 2201 C CB  . TRP B 2 320 ? 125.118 124.568 95.912  1.00 101.60 ? 264 TRP R CB  1 
ATOM 2202 C CG  . TRP B 2 320 ? 124.050 125.088 96.813  1.00 101.60 ? 264 TRP R CG  1 
ATOM 2203 C CD1 . TRP B 2 320 ? 123.891 124.812 98.135  1.00 101.60 ? 264 TRP R CD1 1 
ATOM 2204 C CD2 . TRP B 2 320 ? 122.983 125.972 96.456  1.00 101.60 ? 264 TRP R CD2 1 
ATOM 2205 N NE1 . TRP B 2 320 ? 122.793 125.470 98.627  1.00 101.60 ? 264 TRP R NE1 1 
ATOM 2206 C CE2 . TRP B 2 320 ? 122.218 126.190 97.615  1.00 101.60 ? 264 TRP R CE2 1 
ATOM 2207 C CE3 . TRP B 2 320 ? 122.601 126.600 95.269  1.00 101.60 ? 264 TRP R CE3 1 
ATOM 2208 C CZ2 . TRP B 2 320 ? 121.095 127.010 97.623  1.00 101.60 ? 264 TRP R CZ2 1 
ATOM 2209 C CZ3 . TRP B 2 320 ? 121.485 127.413 95.278  1.00 101.60 ? 264 TRP R CZ3 1 
ATOM 2210 C CH2 . TRP B 2 320 ? 120.745 127.611 96.447  1.00 101.60 ? 264 TRP R CH2 1 
ATOM 2211 N N   . LEU B 2 321 ? 126.259 122.948 93.134  1.00 101.60 ? 265 LEU R N   1 
ATOM 2212 C CA  . LEU B 2 321 ? 127.230 123.145 92.065  1.00 101.60 ? 265 LEU R CA  1 
ATOM 2213 C C   . LEU B 2 321 ? 126.555 123.514 90.747  1.00 101.60 ? 265 LEU R C   1 
ATOM 2214 O O   . LEU B 2 321 ? 126.978 124.475 90.090  1.00 101.60 ? 265 LEU R O   1 
ATOM 2215 C CB  . LEU B 2 321 ? 128.083 121.889 91.888  1.00 101.60 ? 265 LEU R CB  1 
ATOM 2216 C CG  . LEU B 2 321 ? 129.283 122.043 90.957  1.00 101.60 ? 265 LEU R CG  1 
ATOM 2217 C CD1 . LEU B 2 321 ? 130.361 122.874 91.627  1.00 101.60 ? 265 LEU R CD1 1 
ATOM 2218 C CD2 . LEU B 2 321 ? 129.819 120.682 90.559  1.00 101.60 ? 265 LEU R CD2 1 
ATOM 2219 N N   . PRO B 2 322 ? 125.524 122.781 90.315  1.00 101.60 ? 266 PRO R N   1 
ATOM 2220 C CA  . PRO B 2 322 ? 124.937 123.080 88.998  1.00 101.60 ? 266 PRO R CA  1 
ATOM 2221 C C   . PRO B 2 322 ? 124.441 124.507 88.867  1.00 101.60 ? 266 PRO R C   1 
ATOM 2222 O O   . PRO B 2 322 ? 124.622 125.130 87.813  1.00 101.60 ? 266 PRO R O   1 
ATOM 2223 C CB  . PRO B 2 322 ? 123.787 122.069 88.896  1.00 101.60 ? 266 PRO R CB  1 
ATOM 2224 C CG  . PRO B 2 322 ? 124.170 120.973 89.815  1.00 101.60 ? 266 PRO R CG  1 
ATOM 2225 C CD  . PRO B 2 322 ? 124.830 121.658 90.965  1.00 101.60 ? 266 PRO R CD  1 
ATOM 2226 N N   . TYR B 2 323 ? 123.820 125.047 89.916  1.00 101.60 ? 267 TYR R N   1 
ATOM 2227 C CA  . TYR B 2 323 ? 123.295 126.405 89.839  1.00 101.60 ? 267 TYR R CA  1 
ATOM 2228 C C   . TYR B 2 323 ? 124.418 127.407 89.611  1.00 101.60 ? 267 TYR R C   1 
ATOM 2229 O O   . TYR B 2 323 ? 124.310 128.291 88.755  1.00 101.60 ? 267 TYR R O   1 
ATOM 2230 C CB  . TYR B 2 323 ? 122.527 126.739 91.116  1.00 101.60 ? 267 TYR R CB  1 
ATOM 2231 C CG  . TYR B 2 323 ? 121.956 128.136 91.144  1.00 101.60 ? 267 TYR R CG  1 
ATOM 2232 C CD1 . TYR B 2 323 ? 120.939 128.507 90.278  1.00 101.60 ? 267 TYR R CD1 1 
ATOM 2233 C CD2 . TYR B 2 323 ? 122.430 129.083 92.039  1.00 101.60 ? 267 TYR R CD2 1 
ATOM 2234 C CE1 . TYR B 2 323 ? 120.411 129.782 90.301  1.00 101.60 ? 267 TYR R CE1 1 
ATOM 2235 C CE2 . TYR B 2 323 ? 121.908 130.362 92.069  1.00 101.60 ? 267 TYR R CE2 1 
ATOM 2236 C CZ  . TYR B 2 323 ? 120.897 130.705 91.199  1.00 101.60 ? 267 TYR R CZ  1 
ATOM 2237 O OH  . TYR B 2 323 ? 120.374 131.976 91.222  1.00 101.60 ? 267 TYR R OH  1 
ATOM 2238 N N   . ASN B 2 324 ? 125.515 127.271 90.358  1.00 101.60 ? 268 ASN R N   1 
ATOM 2239 C CA  . ASN B 2 324 ? 126.635 128.191 90.194  1.00 101.60 ? 268 ASN R CA  1 
ATOM 2240 C C   . ASN B 2 324 ? 127.301 128.028 88.836  1.00 101.60 ? 268 ASN R C   1 
ATOM 2241 O O   . ASN B 2 324 ? 127.703 129.024 88.221  1.00 101.60 ? 268 ASN R O   1 
ATOM 2242 C CB  . ASN B 2 324 ? 127.650 127.980 91.311  1.00 101.60 ? 268 ASN R CB  1 
ATOM 2243 C CG  . ASN B 2 324 ? 127.270 128.707 92.577  1.00 101.60 ? 268 ASN R CG  1 
ATOM 2244 O OD1 . ASN B 2 324 ? 127.940 129.650 92.989  1.00 101.60 ? 268 ASN R OD1 1 
ATOM 2245 N ND2 . ASN B 2 324 ? 126.181 128.277 93.199  1.00 101.60 ? 268 ASN R ND2 1 
ATOM 2246 N N   . LEU B 2 325 ? 127.434 126.792 88.352  1.00 101.60 ? 269 LEU R N   1 
ATOM 2247 C CA  . LEU B 2 325 ? 128.029 126.587 87.036  1.00 101.60 ? 269 LEU R CA  1 
ATOM 2248 C C   . LEU B 2 325 ? 127.188 127.245 85.951  1.00 101.60 ? 269 LEU R C   1 
ATOM 2249 O O   . LEU B 2 325 ? 127.718 127.931 85.067  1.00 101.60 ? 269 LEU R O   1 
ATOM 2250 C CB  . LEU B 2 325 ? 128.188 125.094 86.756  1.00 101.60 ? 269 LEU R CB  1 
ATOM 2251 C CG  . LEU B 2 325 ? 129.214 124.351 87.611  1.00 101.60 ? 269 LEU R CG  1 
ATOM 2252 C CD1 . LEU B 2 325 ? 129.320 122.911 87.148  1.00 101.60 ? 269 LEU R CD1 1 
ATOM 2253 C CD2 . LEU B 2 325 ? 130.572 125.035 87.563  1.00 101.60 ? 269 LEU R CD2 1 
ATOM 2254 N N   . VAL B 2 326 ? 125.868 127.060 86.007  1.00 102.52 ? 270 VAL R N   1 
ATOM 2255 C CA  . VAL B 2 326 ? 125.000 127.672 85.007  1.00 102.52 ? 270 VAL R CA  1 
ATOM 2256 C C   . VAL B 2 326 ? 125.035 129.189 85.127  1.00 102.52 ? 270 VAL R C   1 
ATOM 2257 O O   . VAL B 2 326 ? 124.984 129.904 84.121  1.00 102.52 ? 270 VAL R O   1 
ATOM 2258 C CB  . VAL B 2 326 ? 123.568 127.128 85.135  1.00 102.52 ? 270 VAL R CB  1 
ATOM 2259 C CG1 . VAL B 2 326 ? 122.642 127.867 84.187  1.00 102.52 ? 270 VAL R CG1 1 
ATOM 2260 C CG2 . VAL B 2 326 ? 123.541 125.634 84.851  1.00 102.52 ? 270 VAL R CG2 1 
ATOM 2261 N N   . LEU B 2 327 ? 125.111 129.710 86.353  1.00 101.60 ? 271 LEU R N   1 
ATOM 2262 C CA  . LEU B 2 327 ? 125.194 131.157 86.522  1.00 101.60 ? 271 LEU R CA  1 
ATOM 2263 C C   . LEU B 2 327 ? 126.461 131.708 85.883  1.00 101.60 ? 271 LEU R C   1 
ATOM 2264 O O   . LEU B 2 327 ? 126.424 132.732 85.189  1.00 101.60 ? 271 LEU R O   1 
ATOM 2265 C CB  . LEU B 2 327 ? 125.150 131.522 88.004  1.00 101.15 ? 271 LEU R CB  1 
ATOM 2266 C CG  . LEU B 2 327 ? 123.875 132.228 88.466  1.00 101.15 ? 271 LEU R CG  1 
ATOM 2267 C CD1 . LEU B 2 327 ? 122.718 131.257 88.471  1.00 101.15 ? 271 LEU R CD1 1 
ATOM 2268 C CD2 . LEU B 2 327 ? 124.063 132.841 89.843  1.00 101.15 ? 271 LEU R CD2 1 
ATOM 2269 N N   . LEU B 2 328 ? 127.595 131.046 86.114  1.00 104.64 ? 272 LEU R N   1 
ATOM 2270 C CA  . LEU B 2 328 ? 128.840 131.495 85.503  1.00 104.64 ? 272 LEU R CA  1 
ATOM 2271 C C   . LEU B 2 328 ? 128.757 131.415 83.986  1.00 104.64 ? 272 LEU R C   1 
ATOM 2272 O O   . LEU B 2 328 ? 129.229 132.315 83.280  1.00 104.64 ? 272 LEU R O   1 
ATOM 2273 C CB  . LEU B 2 328 ? 130.013 130.674 86.018  1.00 30.00  ? 272 LEU R CB  1 
ATOM 2274 N N   . ALA B 2 329 ? 128.158 130.344 83.464  1.00 108.62 ? 273 ALA R N   1 
ATOM 2275 C CA  . ALA B 2 329 ? 127.998 130.234 82.020  1.00 108.62 ? 273 ALA R CA  1 
ATOM 2276 C C   . ALA B 2 329 ? 127.152 131.377 81.475  1.00 108.62 ? 273 ALA R C   1 
ATOM 2277 O O   . ALA B 2 329 ? 127.477 131.955 80.434  1.00 108.62 ? 273 ALA R O   1 
ATOM 2278 C CB  . ALA B 2 329 ? 127.376 128.887 81.659  1.00 108.62 ? 273 ALA R CB  1 
ATOM 2279 N N   . ASP B 2 330 ? 126.061 131.714 82.164  1.00 111.42 ? 274 ASP R N   1 
ATOM 2280 C CA  . ASP B 2 330 ? 125.205 132.807 81.714  1.00 111.42 ? 274 ASP R CA  1 
ATOM 2281 C C   . ASP B 2 330 ? 125.955 134.132 81.731  1.00 111.42 ? 274 ASP R C   1 
ATOM 2282 O O   . ASP B 2 330 ? 125.837 134.937 80.798  1.00 111.42 ? 274 ASP R O   1 
ATOM 2283 C CB  . ASP B 2 330 ? 123.958 132.884 82.594  1.00 111.42 ? 274 ASP R CB  1 
ATOM 2284 C CG  . ASP B 2 330 ? 122.988 133.962 82.148  1.00 111.42 ? 274 ASP R CG  1 
ATOM 2285 O OD1 . ASP B 2 330 ? 123.288 134.679 81.173  1.00 111.42 ? 274 ASP R OD1 1 
ATOM 2286 O OD2 . ASP B 2 330 ? 121.917 134.089 82.776  1.00 111.42 ? 274 ASP R OD2 1 
ATOM 2287 N N   . THR B 2 331 ? 126.723 134.384 82.791  1.00 109.24 ? 275 THR R N   1 
ATOM 2288 C CA  . THR B 2 331 ? 127.491 135.622 82.850  1.00 109.24 ? 275 THR R CA  1 
ATOM 2289 C C   . THR B 2 331 ? 128.499 135.687 81.711  1.00 109.24 ? 275 THR R C   1 
ATOM 2290 O O   . THR B 2 331 ? 128.652 136.731 81.066  1.00 109.24 ? 275 THR R O   1 
ATOM 2291 C CB  . THR B 2 331 ? 128.196 135.744 84.200  1.00 109.24 ? 275 THR R CB  1 
ATOM 2292 O OG1 . THR B 2 331 ? 127.227 135.684 85.253  1.00 109.24 ? 275 THR R OG1 1 
ATOM 2293 C CG2 . THR B 2 331 ? 128.952 137.061 84.292  1.00 109.24 ? 275 THR R CG2 1 
ATOM 2294 N N   . LEU B 2 332 ? 129.183 134.576 81.436  1.00 111.61 ? 276 LEU R N   1 
ATOM 2295 C CA  . LEU B 2 332 ? 130.131 134.559 80.329  1.00 111.61 ? 276 LEU R CA  1 
ATOM 2296 C C   . LEU B 2 332 ? 129.425 134.802 79.001  1.00 111.61 ? 276 LEU R C   1 
ATOM 2297 O O   . LEU B 2 332 ? 129.937 135.530 78.143  1.00 111.61 ? 276 LEU R O   1 
ATOM 2298 C CB  . LEU B 2 332 ? 130.886 133.233 80.307  1.00 111.61 ? 276 LEU R CB  1 
ATOM 2299 C CG  . LEU B 2 332 ? 132.045 133.144 81.302  1.00 111.61 ? 276 LEU R CG  1 
ATOM 2300 C CD1 . LEU B 2 332 ? 132.282 131.708 81.735  1.00 111.61 ? 276 LEU R CD1 1 
ATOM 2301 C CD2 . LEU B 2 332 ? 133.307 133.738 80.705  1.00 111.61 ? 276 LEU R CD2 1 
ATOM 2302 N N   . MET B 2 333 ? 128.248 134.203 78.814  1.00 117.97 ? 277 MET R N   1 
ATOM 2303 C CA  . MET B 2 333 ? 127.498 134.422 77.583  1.00 117.97 ? 277 MET R CA  1 
ATOM 2304 C C   . MET B 2 333 ? 127.125 135.887 77.414  1.00 117.97 ? 277 MET R C   1 
ATOM 2305 O O   . MET B 2 333 ? 127.251 136.433 76.313  1.00 117.97 ? 277 MET R O   1 
ATOM 2306 C CB  . MET B 2 333 ? 126.238 133.559 77.571  1.00 117.97 ? 277 MET R CB  1 
ATOM 2307 C CG  . MET B 2 333 ? 125.414 133.695 76.304  1.00 117.97 ? 277 MET R CG  1 
ATOM 2308 S SD  . MET B 2 333 ? 123.956 132.642 76.314  1.00 117.97 ? 277 MET R SD  1 
ATOM 2309 C CE  . MET B 2 333 ? 122.688 133.846 76.696  1.00 117.97 ? 277 MET R CE  1 
ATOM 2310 N N   . ARG B 2 334 ? 126.665 136.536 78.480  1.00 114.68 ? 278 ARG R N   1 
ATOM 2311 C CA  . ARG B 2 334 ? 126.392 137.965 78.415  1.00 114.68 ? 278 ARG R CA  1 
ATOM 2312 C C   . ARG B 2 334 ? 127.652 138.791 78.211  1.00 114.68 ? 278 ARG R C   1 
ATOM 2313 O O   . ARG B 2 334 ? 127.564 139.918 77.709  1.00 114.68 ? 278 ARG R O   1 
ATOM 2314 C CB  . ARG B 2 334 ? 125.679 138.438 79.683  1.00 114.68 ? 278 ARG R CB  1 
ATOM 2315 C CG  . ARG B 2 334 ? 124.251 137.953 79.804  1.00 114.68 ? 278 ARG R CG  1 
ATOM 2316 C CD  . ARG B 2 334 ? 123.544 138.649 80.946  1.00 114.68 ? 278 ARG R CD  1 
ATOM 2317 N NE  . ARG B 2 334 ? 122.229 138.074 81.207  1.00 114.68 ? 278 ARG R NE  1 
ATOM 2318 C CZ  . ARG B 2 334 ? 121.073 138.679 80.963  1.00 114.68 ? 278 ARG R CZ  1 
ATOM 2319 N NH1 . ARG B 2 334 ? 121.018 139.883 80.415  1.00 114.68 ? 278 ARG R NH1 1 
ATOM 2320 N NH2 . ARG B 2 334 ? 119.940 138.058 81.274  1.00 114.68 ? 278 ARG R NH2 1 
ATOM 2321 N N   . THR B 2 335 ? 128.816 138.261 78.582  1.00 114.50 ? 279 THR R N   1 
ATOM 2322 C CA  . THR B 2 335 ? 130.081 138.931 78.321  1.00 114.50 ? 279 THR R CA  1 
ATOM 2323 C C   . THR B 2 335 ? 130.600 138.689 76.911  1.00 114.50 ? 279 THR R C   1 
ATOM 2324 O O   . THR B 2 335 ? 131.641 139.246 76.548  1.00 114.50 ? 279 THR R O   1 
ATOM 2325 C CB  . THR B 2 335 ? 131.142 138.470 79.327  1.00 114.50 ? 279 THR R CB  1 
ATOM 2326 O OG1 . THR B 2 335 ? 130.576 138.437 80.642  1.00 114.50 ? 279 THR R OG1 1 
ATOM 2327 C CG2 . THR B 2 335 ? 132.337 139.413 79.322  1.00 114.50 ? 279 THR R CG2 1 
ATOM 2328 N N   . GLN B 2 336 ? 129.906 137.871 76.119  1.00 118.20 ? 280 GLN R N   1 
ATOM 2329 C CA  . GLN B 2 336 ? 130.306 137.550 74.752  1.00 118.20 ? 280 GLN R CA  1 
ATOM 2330 C C   . GLN B 2 336 ? 131.594 136.733 74.723  1.00 118.20 ? 280 GLN R C   1 
ATOM 2331 O O   . GLN B 2 336 ? 132.189 136.545 73.657  1.00 118.20 ? 280 GLN R O   1 
ATOM 2332 C CB  . GLN B 2 336 ? 130.468 138.824 73.936  1.00 30.00  ? 280 GLN R CB  1 
ATOM 2333 N N   . VAL B 2 337 ? 132.032 136.237 75.881  1.00 115.38 ? 281 VAL R N   1 
ATOM 2334 C CA  . VAL B 2 337 ? 133.174 135.330 75.904  1.00 115.38 ? 281 VAL R CA  1 
ATOM 2335 C C   . VAL B 2 337 ? 132.838 134.046 75.157  1.00 115.38 ? 281 VAL R C   1 
ATOM 2336 O O   . VAL B 2 337 ? 133.638 133.544 74.359  1.00 115.38 ? 281 VAL R O   1 
ATOM 2337 C CB  . VAL B 2 337 ? 133.601 135.046 77.354  1.00 115.38 ? 281 VAL R CB  1 
ATOM 2338 C CG1 . VAL B 2 337 ? 134.673 133.970 77.392  1.00 115.38 ? 281 VAL R CG1 1 
ATOM 2339 C CG2 . VAL B 2 337 ? 134.096 136.319 78.015  1.00 115.38 ? 281 VAL R CG2 1 
ATOM 2340 N N   . ILE B 2 338 ? 131.650 133.499 75.402  1.00 117.82 ? 282 ILE R N   1 
ATOM 2341 C CA  . ILE B 2 338 ? 131.154 132.315 74.711  1.00 117.82 ? 282 ILE R CA  1 
ATOM 2342 C C   . ILE B 2 338 ? 130.214 132.768 73.606  1.00 117.82 ? 282 ILE R C   1 
ATOM 2343 O O   . ILE B 2 338 ? 129.368 133.645 73.818  1.00 117.82 ? 282 ILE R O   1 
ATOM 2344 C CB  . ILE B 2 338 ? 130.436 131.359 75.682  1.00 117.82 ? 282 ILE R CB  1 
ATOM 2345 C CG1 . ILE B 2 338 ? 131.391 130.904 76.786  1.00 117.82 ? 282 ILE R CG1 1 
ATOM 2346 C CG2 . ILE B 2 338 ? 129.879 130.158 74.928  1.00 117.82 ? 282 ILE R CG2 1 
ATOM 2347 C CD1 . ILE B 2 338 ? 130.721 130.107 77.885  1.00 117.82 ? 282 ILE R CD1 1 
ATOM 2348 N N   . GLN B 2 339 ? 130.360 132.177 72.423  1.00 125.50 ? 283 GLN R N   1 
ATOM 2349 C CA  . GLN B 2 339 ? 129.514 132.563 71.303  1.00 125.50 ? 283 GLN R CA  1 
ATOM 2350 C C   . GLN B 2 339 ? 128.047 132.391 71.673  1.00 125.50 ? 283 GLN R C   1 
ATOM 2351 O O   . GLN B 2 339 ? 127.646 131.372 72.241  1.00 125.50 ? 283 GLN R O   1 
ATOM 2352 C CB  . GLN B 2 339 ? 129.851 131.730 70.067  1.00 125.50 ? 283 GLN R CB  1 
ATOM 2353 C CG  . GLN B 2 339 ? 129.243 132.275 68.783  1.00 125.50 ? 283 GLN R CG  1 
ATOM 2354 C CD  . GLN B 2 339 ? 130.091 131.986 67.559  1.00 125.50 ? 283 GLN R CD  1 
ATOM 2355 O OE1 . GLN B 2 339 ? 131.133 131.338 67.648  1.00 125.50 ? 283 GLN R OE1 1 
ATOM 2356 N NE2 . GLN B 2 339 ? 129.647 132.473 66.406  1.00 125.50 ? 283 GLN R NE2 1 
ATOM 2357 N N   . GLU B 2 340 ? 127.245 133.399 71.344  1.00 127.62 ? 284 GLU R N   1 
ATOM 2358 C CA  . GLU B 2 340 ? 125.856 133.485 71.776  1.00 127.62 ? 284 GLU R CA  1 
ATOM 2359 C C   . GLU B 2 340 ? 124.940 133.187 70.597  1.00 127.62 ? 284 GLU R C   1 
ATOM 2360 O O   . GLU B 2 340 ? 125.075 133.795 69.531  1.00 127.62 ? 284 GLU R O   1 
ATOM 2361 C CB  . GLU B 2 340 ? 125.558 134.869 72.351  1.00 127.62 ? 284 GLU R CB  1 
ATOM 2362 C CG  . GLU B 2 340 ? 124.189 134.996 72.990  1.00 127.62 ? 284 GLU R CG  1 
ATOM 2363 C CD  . GLU B 2 340 ? 124.007 136.317 73.708  1.00 127.62 ? 284 GLU R CD  1 
ATOM 2364 O OE1 . GLU B 2 340 ? 124.970 137.111 73.748  1.00 127.62 ? 284 GLU R OE1 1 
ATOM 2365 O OE2 . GLU B 2 340 ? 122.900 136.562 74.233  1.00 127.62 ? 284 GLU R OE2 1 
ATOM 2366 N N   . THR B 2 341 ? 124.013 132.252 70.794  1.00 129.51 ? 285 THR R N   1 
ATOM 2367 C CA  . THR B 2 341 ? 123.017 131.908 69.792  1.00 129.51 ? 285 THR R CA  1 
ATOM 2368 C C   . THR B 2 341 ? 121.671 131.714 70.475  1.00 129.51 ? 285 THR R C   1 
ATOM 2369 O O   . THR B 2 341 ? 121.594 131.338 71.647  1.00 129.51 ? 285 THR R O   1 
ATOM 2370 C CB  . THR B 2 341 ? 123.394 130.635 69.026  1.00 129.51 ? 285 THR R CB  1 
ATOM 2371 O OG1 . THR B 2 341 ? 123.405 129.520 69.925  1.00 129.51 ? 285 THR R OG1 1 
ATOM 2372 C CG2 . THR B 2 341 ? 124.766 130.782 68.390  1.00 129.51 ? 285 THR R CG2 1 
ATOM 2373 N N   . CYS B 2 342 ? 120.604 131.962 69.713  1.00 131.89 ? 286 CYS R N   1 
ATOM 2374 C CA  . CYS B 2 342 ? 119.257 131.873 70.269  1.00 131.89 ? 286 CYS R CA  1 
ATOM 2375 C C   . CYS B 2 342 ? 119.038 130.537 70.970  1.00 131.89 ? 286 CYS R C   1 
ATOM 2376 O O   . CYS B 2 342 ? 118.489 130.487 72.080  1.00 131.89 ? 286 CYS R O   1 
ATOM 2377 C CB  . CYS B 2 342 ? 118.230 132.080 69.156  1.00 131.89 ? 286 CYS R CB  1 
ATOM 2378 S SG  . CYS B 2 342 ? 116.505 132.017 69.685  1.00 131.89 ? 286 CYS R SG  1 
ATOM 2379 N N   . GLU B 2 343 ? 119.473 129.443 70.344  1.00 129.88 ? 287 GLU R N   1 
ATOM 2380 C CA  . GLU B 2 343 ? 119.330 128.137 70.974  1.00 129.88 ? 287 GLU R CA  1 
ATOM 2381 C C   . GLU B 2 343 ? 120.151 128.041 72.252  1.00 129.88 ? 287 GLU R C   1 
ATOM 2382 O O   . GLU B 2 343 ? 119.705 127.422 73.223  1.00 129.88 ? 287 GLU R O   1 
ATOM 2383 C CB  . GLU B 2 343 ? 119.730 127.036 70.004  1.00 30.00  ? 287 GLU R CB  1 
ATOM 2384 N N   . ARG B 2 344 ? 121.348 128.632 72.277  1.00 125.89 ? 288 ARG R N   1 
ATOM 2385 C CA  . ARG B 2 344 ? 122.108 128.678 73.523  1.00 125.89 ? 288 ARG R CA  1 
ATOM 2386 C C   . ARG B 2 344 ? 121.352 129.448 74.596  1.00 125.89 ? 288 ARG R C   1 
ATOM 2387 O O   . ARG B 2 344 ? 121.336 129.043 75.766  1.00 125.89 ? 288 ARG R O   1 
ATOM 2388 C CB  . ARG B 2 344 ? 123.484 129.303 73.288  1.00 125.89 ? 288 ARG R CB  1 
ATOM 2389 C CG  . ARG B 2 344 ? 124.586 128.293 73.026  1.00 125.89 ? 288 ARG R CG  1 
ATOM 2390 C CD  . ARG B 2 344 ? 125.952 128.962 73.005  1.00 125.89 ? 288 ARG R CD  1 
ATOM 2391 N NE  . ARG B 2 344 ? 127.044 127.996 73.039  1.00 125.89 ? 288 ARG R NE  1 
ATOM 2392 C CZ  . ARG B 2 344 ? 127.341 127.233 74.083  1.00 125.89 ? 288 ARG R CZ  1 
ATOM 2393 N NH1 . ARG B 2 344 ? 126.657 127.309 75.213  1.00 125.89 ? 288 ARG R NH1 1 
ATOM 2394 N NH2 . ARG B 2 344 ? 128.354 126.377 73.992  1.00 125.89 ? 288 ARG R NH2 1 
ATOM 2395 N N   . ARG B 2 345 ? 120.733 130.570 74.221  1.00 127.36 ? 289 ARG R N   1 
ATOM 2396 C CA  . ARG B 2 345 ? 119.916 131.304 75.179  1.00 127.36 ? 289 ARG R CA  1 
ATOM 2397 C C   . ARG B 2 345 ? 118.835 130.407 75.761  1.00 127.36 ? 289 ARG R C   1 
ATOM 2398 O O   . ARG B 2 345 ? 118.663 130.342 76.983  1.00 127.36 ? 289 ARG R O   1 
ATOM 2399 C CB  . ARG B 2 345 ? 119.277 132.525 74.515  1.00 127.36 ? 289 ARG R CB  1 
ATOM 2400 C CG  . ARG B 2 345 ? 120.233 133.451 73.783  1.00 127.36 ? 289 ARG R CG  1 
ATOM 2401 C CD  . ARG B 2 345 ? 119.456 134.493 72.994  1.00 127.36 ? 289 ARG R CD  1 
ATOM 2402 N NE  . ARG B 2 345 ? 119.678 135.852 73.472  1.00 127.36 ? 289 ARG R NE  1 
ATOM 2403 C CZ  . ARG B 2 345 ? 118.939 136.896 73.122  1.00 127.36 ? 289 ARG R CZ  1 
ATOM 2404 N NH1 . ARG B 2 345 ? 117.883 136.764 72.335  1.00 127.36 ? 289 ARG R NH1 1 
ATOM 2405 N NH2 . ARG B 2 345 ? 119.265 138.103 73.574  1.00 127.36 ? 289 ARG R NH2 1 
ATOM 2406 N N   . ASN B 2 346 ? 118.102 129.701 74.899  1.00 124.65 ? 290 ASN R N   1 
ATOM 2407 C CA  . ASN B 2 346 ? 117.027 128.839 75.382  1.00 124.65 ? 290 ASN R CA  1 
ATOM 2408 C C   . ASN B 2 346 ? 117.567 127.742 76.292  1.00 124.65 ? 290 ASN R C   1 
ATOM 2409 O O   . ASN B 2 346 ? 116.987 127.457 77.351  1.00 124.65 ? 290 ASN R O   1 
ATOM 2410 C CB  . ASN B 2 346 ? 116.280 128.235 74.193  1.00 124.65 ? 290 ASN R CB  1 
ATOM 2411 C CG  . ASN B 2 346 ? 114.969 127.593 74.591  1.00 124.65 ? 290 ASN R CG  1 
ATOM 2412 O OD1 . ASN B 2 346 ? 114.699 127.386 75.773  1.00 124.65 ? 290 ASN R OD1 1 
ATOM 2413 N ND2 . ASN B 2 346 ? 114.146 127.271 73.602  1.00 124.65 ? 290 ASN R ND2 1 
ATOM 2414 N N   . HIS B 2 347 ? 118.677 127.116 75.897  1.00 123.57 ? 291 HIS R N   1 
ATOM 2415 C CA  . HIS B 2 347 ? 119.255 126.041 76.693  1.00 123.57 ? 291 HIS R CA  1 
ATOM 2416 C C   . HIS B 2 347 ? 119.621 126.535 78.084  1.00 123.57 ? 291 HIS R C   1 
ATOM 2417 O O   . HIS B 2 347 ? 119.231 125.937 79.093  1.00 123.57 ? 291 HIS R O   1 
ATOM 2418 C CB  . HIS B 2 347 ? 120.489 125.471 75.989  1.00 123.57 ? 291 HIS R CB  1 
ATOM 2419 C CG  . HIS B 2 347 ? 120.174 124.645 74.781  1.00 123.57 ? 291 HIS R CG  1 
ATOM 2420 N ND1 . HIS B 2 347 ? 121.136 124.265 73.871  1.00 123.57 ? 291 HIS R ND1 1 
ATOM 2421 C CD2 . HIS B 2 347 ? 119.007 124.123 74.335  1.00 123.57 ? 291 HIS R CD2 1 
ATOM 2422 C CE1 . HIS B 2 347 ? 120.576 123.547 72.914  1.00 123.57 ? 291 HIS R CE1 1 
ATOM 2423 N NE2 . HIS B 2 347 ? 119.284 123.446 73.172  1.00 123.57 ? 291 HIS R NE2 1 
ATOM 2424 N N   . ILE B 2 348 ? 120.378 127.632 78.155  1.00 116.05 ? 292 ILE R N   1 
ATOM 2425 C CA  . ILE B 2 348 ? 120.809 128.144 79.452  1.00 116.05 ? 292 ILE R CA  1 
ATOM 2426 C C   . ILE B 2 348 ? 119.605 128.578 80.272  1.00 116.05 ? 292 ILE R C   1 
ATOM 2427 O O   . ILE B 2 348 ? 119.569 128.399 81.495  1.00 116.05 ? 292 ILE R O   1 
ATOM 2428 C CB  . ILE B 2 348 ? 121.817 129.293 79.265  1.00 116.05 ? 292 ILE R CB  1 
ATOM 2429 C CG1 . ILE B 2 348 ? 123.213 128.722 79.007  1.00 116.05 ? 292 ILE R CG1 1 
ATOM 2430 C CG2 . ILE B 2 348 ? 121.830 130.203 80.489  1.00 116.05 ? 292 ILE R CG2 1 
ATOM 2431 C CD1 . ILE B 2 348 ? 124.245 129.757 78.624  1.00 116.05 ? 292 ILE R CD1 1 
ATOM 2432 N N   . ASP B 2 349 ? 118.598 129.153 79.615  1.00 117.07 ? 293 ASP R N   1 
ATOM 2433 C CA  . ASP B 2 349 ? 117.428 129.632 80.338  1.00 117.07 ? 293 ASP R CA  1 
ATOM 2434 C C   . ASP B 2 349 ? 116.677 128.481 80.993  1.00 117.07 ? 293 ASP R C   1 
ATOM 2435 O O   . ASP B 2 349 ? 116.253 128.586 82.149  1.00 117.07 ? 293 ASP R O   1 
ATOM 2436 C CB  . ASP B 2 349 ? 116.519 130.400 79.384  1.00 117.07 ? 293 ASP R CB  1 
ATOM 2437 C CG  . ASP B 2 349 ? 115.595 131.351 80.102  1.00 117.07 ? 293 ASP R CG  1 
ATOM 2438 O OD1 . ASP B 2 349 ? 115.363 131.159 81.315  1.00 117.07 ? 293 ASP R OD1 1 
ATOM 2439 O OD2 . ASP B 2 349 ? 115.116 132.303 79.454  1.00 117.07 ? 293 ASP R OD2 1 
ATOM 2440 N N   . ARG B 2 350 ? 116.499 127.374 80.271  1.00 114.69 ? 294 ARG R N   1 
ATOM 2441 C CA  . ARG B 2 350 ? 115.850 126.213 80.874  1.00 114.69 ? 294 ARG R CA  1 
ATOM 2442 C C   . ARG B 2 350 ? 116.727 125.579 81.948  1.00 114.69 ? 294 ARG R C   1 
ATOM 2443 O O   . ARG B 2 350 ? 116.220 125.138 82.994  1.00 114.69 ? 294 ARG R O   1 
ATOM 2444 C CB  . ARG B 2 350 ? 115.506 125.188 79.795  1.00 114.69 ? 294 ARG R CB  1 
ATOM 2445 C CG  . ARG B 2 350 ? 114.415 124.212 80.200  1.00 114.69 ? 294 ARG R CG  1 
ATOM 2446 C CD  . ARG B 2 350 ? 114.578 122.867 79.507  1.00 114.69 ? 294 ARG R CD  1 
ATOM 2447 N NE  . ARG B 2 350 ? 115.022 123.015 78.125  1.00 114.69 ? 294 ARG R NE  1 
ATOM 2448 C CZ  . ARG B 2 350 ? 114.300 122.713 77.053  1.00 114.69 ? 294 ARG R CZ  1 
ATOM 2449 N NH1 . ARG B 2 350 ? 113.065 122.246 77.154  1.00 114.69 ? 294 ARG R NH1 1 
ATOM 2450 N NH2 . ARG B 2 350 ? 114.829 122.887 75.846  1.00 114.69 ? 294 ARG R NH2 1 
ATOM 2451 N N   . ALA B 2 351 ? 118.040 125.530 81.710  1.00 108.80 ? 295 ALA R N   1 
ATOM 2452 C CA  . ALA B 2 351 ? 118.946 124.932 82.681  1.00 108.80 ? 295 ALA R CA  1 
ATOM 2453 C C   . ALA B 2 351 ? 118.924 125.701 83.992  1.00 108.80 ? 295 ALA R C   1 
ATOM 2454 O O   . ALA B 2 351 ? 119.050 125.109 85.067  1.00 108.80 ? 295 ALA R O   1 
ATOM 2455 C CB  . ALA B 2 351 ? 120.363 124.883 82.114  1.00 108.80 ? 295 ALA R CB  1 
ATOM 2456 N N   . LEU B 2 352 ? 118.789 127.026 83.924  1.00 107.90 ? 296 LEU R N   1 
ATOM 2457 C CA  . LEU B 2 352 ? 118.710 127.817 85.147  1.00 107.90 ? 296 LEU R CA  1 
ATOM 2458 C C   . LEU B 2 352 ? 117.567 127.346 86.029  1.00 107.90 ? 296 LEU R C   1 
ATOM 2459 O O   . LEU B 2 352 ? 117.756 127.088 87.223  1.00 107.90 ? 296 LEU R O   1 
ATOM 2460 C CB  . LEU B 2 352 ? 118.532 129.295 84.803  1.00 107.90 ? 296 LEU R CB  1 
ATOM 2461 C CG  . LEU B 2 352 ? 119.816 130.089 84.574  1.00 107.90 ? 296 LEU R CG  1 
ATOM 2462 C CD1 . LEU B 2 352 ? 119.493 131.461 84.016  1.00 107.90 ? 296 LEU R CD1 1 
ATOM 2463 C CD2 . LEU B 2 352 ? 120.603 130.223 85.870  1.00 107.90 ? 296 LEU R CD2 1 
ATOM 2464 N N   . ASP B 2 353 ? 116.370 127.228 85.457  1.00 106.60 ? 297 ASP R N   1 
ATOM 2465 C CA  . ASP B 2 353 ? 115.222 126.801 86.245  1.00 106.60 ? 297 ASP R CA  1 
ATOM 2466 C C   . ASP B 2 353 ? 115.416 125.385 86.768  1.00 106.60 ? 297 ASP R C   1 
ATOM 2467 O O   . ASP B 2 353 ? 115.114 125.099 87.935  1.00 106.60 ? 297 ASP R O   1 
ATOM 2468 C CB  . ASP B 2 353 ? 113.952 126.893 85.404  1.00 106.60 ? 297 ASP R CB  1 
ATOM 2469 C CG  . ASP B 2 353 ? 112.697 126.826 86.242  1.00 106.60 ? 297 ASP R CG  1 
ATOM 2470 O OD1 . ASP B 2 353 ? 112.781 126.360 87.396  1.00 106.60 ? 297 ASP R OD1 1 
ATOM 2471 O OD2 . ASP B 2 353 ? 111.629 127.245 85.750  1.00 106.60 ? 297 ASP R OD2 1 
ATOM 2472 N N   . ALA B 2 354 ? 115.922 124.483 85.923  1.00 106.61 ? 298 ALA R N   1 
ATOM 2473 C CA  . ALA B 2 354 ? 116.122 123.109 86.375  1.00 106.61 ? 298 ALA R CA  1 
ATOM 2474 C C   . ALA B 2 354 ? 117.095 123.053 87.548  1.00 106.61 ? 298 ALA R C   1 
ATOM 2475 O O   . ALA B 2 354 ? 116.841 122.368 88.550  1.00 106.61 ? 298 ALA R O   1 
ATOM 2476 C CB  . ALA B 2 354 ? 116.624 122.246 85.220  1.00 106.61 ? 298 ALA R CB  1 
ATOM 2477 N N   . THR B 2 355 ? 118.209 123.776 87.446  1.00 102.65 ? 299 THR R N   1 
ATOM 2478 C CA  . THR B 2 355 ? 119.197 123.777 88.514  1.00 102.65 ? 299 THR R CA  1 
ATOM 2479 C C   . THR B 2 355 ? 118.658 124.429 89.775  1.00 102.65 ? 299 THR R C   1 
ATOM 2480 O O   . THR B 2 355 ? 118.979 123.982 90.878  1.00 102.65 ? 299 THR R O   1 
ATOM 2481 C CB  . THR B 2 355 ? 120.463 124.492 88.054  1.00 102.65 ? 299 THR R CB  1 
ATOM 2482 O OG1 . THR B 2 355 ? 120.103 125.692 87.359  1.00 102.65 ? 299 THR R OG1 1 
ATOM 2483 C CG2 . THR B 2 355 ? 121.275 123.596 87.134  1.00 102.65 ? 299 THR R CG2 1 
ATOM 2484 N N   . GLU B 2 356 ? 117.858 125.488 89.646  1.00 104.80 ? 300 GLU R N   1 
ATOM 2485 C CA  . GLU B 2 356 ? 117.247 126.073 90.834  1.00 104.80 ? 300 GLU R CA  1 
ATOM 2486 C C   . GLU B 2 356 ? 116.351 125.062 91.530  1.00 104.80 ? 300 GLU R C   1 
ATOM 2487 O O   . GLU B 2 356 ? 116.387 124.927 92.761  1.00 104.80 ? 300 GLU R O   1 
ATOM 2488 C CB  . GLU B 2 356 ? 116.449 127.323 90.468  1.00 104.80 ? 300 GLU R CB  1 
ATOM 2489 C CG  . GLU B 2 356 ? 117.239 128.612 90.568  1.00 104.80 ? 300 GLU R CG  1 
ATOM 2490 C CD  . GLU B 2 356 ? 116.384 129.839 90.329  1.00 104.80 ? 300 GLU R CD  1 
ATOM 2491 O OE1 . GLU B 2 356 ? 115.174 129.680 90.058  1.00 104.80 ? 300 GLU R OE1 1 
ATOM 2492 O OE2 . GLU B 2 356 ? 116.921 130.964 90.413  1.00 104.80 ? 300 GLU R OE2 1 
ATOM 2493 N N   . ILE B 2 357 ? 115.541 124.338 90.757  1.00 104.10 ? 301 ILE R N   1 
ATOM 2494 C CA  . ILE B 2 357 ? 114.675 123.327 91.355  1.00 104.10 ? 301 ILE R CA  1 
ATOM 2495 C C   . ILE B 2 357 ? 115.513 122.295 92.091  1.00 104.10 ? 301 ILE R C   1 
ATOM 2496 O O   . ILE B 2 357 ? 115.220 121.938 93.238  1.00 104.10 ? 301 ILE R O   1 
ATOM 2497 C CB  . ILE B 2 357 ? 113.795 122.665 90.281  1.00 104.10 ? 301 ILE R CB  1 
ATOM 2498 C CG1 . ILE B 2 357 ? 112.885 123.697 89.619  1.00 104.10 ? 301 ILE R CG1 1 
ATOM 2499 C CG2 . ILE B 2 357 ? 112.961 121.554 90.896  1.00 104.10 ? 301 ILE R CG2 1 
ATOM 2500 C CD1 . ILE B 2 357 ? 112.528 123.345 88.199  1.00 104.10 ? 301 ILE R CD1 1 
ATOM 2501 N N   . LEU B 2 358 ? 116.575 121.806 91.449  1.00 101.65 ? 302 LEU R N   1 
ATOM 2502 C CA  . LEU B 2 358 ? 117.406 120.791 92.089  1.00 101.65 ? 302 LEU R CA  1 
ATOM 2503 C C   . LEU B 2 358 ? 118.055 121.327 93.358  1.00 101.65 ? 302 LEU R C   1 
ATOM 2504 O O   . LEU B 2 358 ? 118.099 120.634 94.380  1.00 101.65 ? 302 LEU R O   1 
ATOM 2505 C CB  . LEU B 2 358 ? 118.475 120.292 91.118  1.00 101.65 ? 302 LEU R CB  1 
ATOM 2506 C CG  . LEU B 2 358 ? 119.375 119.178 91.656  1.00 101.65 ? 302 LEU R CG  1 
ATOM 2507 C CD1 . LEU B 2 358 ? 118.556 117.953 92.024  1.00 101.65 ? 302 LEU R CD1 1 
ATOM 2508 C CD2 . LEU B 2 358 ? 120.445 118.821 90.640  1.00 101.65 ? 302 LEU R CD2 1 
ATOM 2509 N N   . GLY B 2 359 ? 118.565 122.556 93.312  1.00 101.60 ? 303 GLY R N   1 
ATOM 2510 C CA  . GLY B 2 359 ? 119.268 123.101 94.460  1.00 101.60 ? 303 GLY R CA  1 
ATOM 2511 C C   . GLY B 2 359 ? 118.358 123.361 95.642  1.00 101.60 ? 303 GLY R C   1 
ATOM 2512 O O   . GLY B 2 359 ? 118.755 123.167 96.794  1.00 101.60 ? 303 GLY R O   1 
ATOM 2513 N N   . ILE B 2 360 ? 117.125 123.800 95.381  1.00 101.60 ? 304 ILE R N   1 
ATOM 2514 C CA  . ILE B 2 360 ? 116.210 124.143 96.459  1.00 101.60 ? 304 ILE R CA  1 
ATOM 2515 C C   . ILE B 2 360 ? 116.086 123.038 97.501  1.00 101.60 ? 304 ILE R C   1 
ATOM 2516 O O   . ILE B 2 360 ? 115.689 123.313 98.636  1.00 101.60 ? 304 ILE R O   1 
ATOM 2517 C CB  . ILE B 2 360 ? 114.832 124.506 95.863  1.00 101.60 ? 304 ILE R CB  1 
ATOM 2518 C CG1 . ILE B 2 360 ? 114.818 125.975 95.445  1.00 101.60 ? 304 ILE R CG1 1 
ATOM 2519 C CG2 . ILE B 2 360 ? 113.716 124.245 96.853  1.00 101.60 ? 304 ILE R CG2 1 
ATOM 2520 C CD1 . ILE B 2 360 ? 113.706 126.328 94.483  1.00 101.60 ? 304 ILE R CD1 1 
ATOM 2521 N N   . LEU B 2 361 ? 116.445 121.800 97.160  1.00 101.60 ? 305 LEU R N   1 
ATOM 2522 C CA  . LEU B 2 361 ? 116.363 120.681 98.094  1.00 101.60 ? 305 LEU R CA  1 
ATOM 2523 C C   . LEU B 2 361 ? 117.295 120.820 99.291  1.00 101.60 ? 305 LEU R C   1 
ATOM 2524 O O   . LEU B 2 361 ? 117.332 119.912 100.132 1.00 101.60 ? 305 LEU R O   1 
ATOM 2525 C CB  . LEU B 2 361 ? 116.675 119.368 97.372  1.00 101.60 ? 305 LEU R CB  1 
ATOM 2526 C CG  . LEU B 2 361 ? 115.732 118.966 96.241  1.00 101.60 ? 305 LEU R CG  1 
ATOM 2527 C CD1 . LEU B 2 361 ? 116.211 117.686 95.585  1.00 101.60 ? 305 LEU R CD1 1 
ATOM 2528 C CD2 . LEU B 2 361 ? 114.318 118.800 96.762  1.00 101.60 ? 305 LEU R CD2 1 
ATOM 2529 N N   . HIS B 2 362 ? 118.071 121.903 99.381  1.00 101.60 ? 306 HIS R N   1 
ATOM 2530 C CA  . HIS B 2 362 ? 118.887 122.115 100.567 1.00 101.60 ? 306 HIS R CA  1 
ATOM 2531 C C   . HIS B 2 362 ? 118.032 122.285 101.811 1.00 101.60 ? 306 HIS R C   1 
ATOM 2532 O O   . HIS B 2 362 ? 118.458 121.890 102.900 1.00 101.60 ? 306 HIS R O   1 
ATOM 2533 C CB  . HIS B 2 362 ? 119.789 123.336 100.385 1.00 101.60 ? 306 HIS R CB  1 
ATOM 2534 C CG  . HIS B 2 362 ? 119.111 124.640 100.671 1.00 101.60 ? 306 HIS R CG  1 
ATOM 2535 N ND1 . HIS B 2 362 ? 119.077 125.201 101.930 1.00 101.60 ? 306 HIS R ND1 1 
ATOM 2536 C CD2 . HIS B 2 362 ? 118.444 125.495 99.861  1.00 101.60 ? 306 HIS R CD2 1 
ATOM 2537 C CE1 . HIS B 2 362 ? 118.418 126.345 101.882 1.00 101.60 ? 306 HIS R CE1 1 
ATOM 2538 N NE2 . HIS B 2 362 ? 118.023 126.546 100.639 1.00 101.60 ? 306 HIS R NE2 1 
ATOM 2539 N N   . SER B 2 363 ? 116.838 122.855 101.673 1.00 101.60 ? 307 SER R N   1 
ATOM 2540 C CA  . SER B 2 363 ? 115.918 122.997 102.790 1.00 101.60 ? 307 SER R CA  1 
ATOM 2541 C C   . SER B 2 363 ? 115.241 121.689 103.166 1.00 101.60 ? 307 SER R C   1 
ATOM 2542 O O   . SER B 2 363 ? 114.793 121.548 104.308 1.00 101.60 ? 307 SER R O   1 
ATOM 2543 C CB  . SER B 2 363 ? 114.846 124.038 102.459 1.00 101.60 ? 307 SER R CB  1 
ATOM 2544 O OG  . SER B 2 363 ? 113.971 123.555 101.455 1.00 101.60 ? 307 SER R OG  1 
ATOM 2545 N N   . CYS B 2 364 ? 115.159 120.735 102.243 1.00 101.60 ? 308 CYS R N   1 
ATOM 2546 C CA  . CYS B 2 364 ? 114.509 119.460 102.508 1.00 101.60 ? 308 CYS R CA  1 
ATOM 2547 C C   . CYS B 2 364 ? 115.458 118.401 103.039 1.00 101.60 ? 308 CYS R C   1 
ATOM 2548 O O   . CYS B 2 364 ? 115.073 117.629 103.921 1.00 101.60 ? 308 CYS R O   1 
ATOM 2549 C CB  . CYS B 2 364 ? 113.846 118.928 101.235 1.00 101.60 ? 308 CYS R CB  1 
ATOM 2550 S SG  . CYS B 2 364 ? 112.185 119.565 100.951 1.00 101.60 ? 308 CYS R SG  1 
ATOM 2551 N N   . LEU B 2 365 ? 116.684 118.340 102.526 1.00 101.60 ? 309 LEU R N   1 
ATOM 2552 C CA  . LEU B 2 365 ? 117.624 117.304 102.929 1.00 101.60 ? 309 LEU R CA  1 
ATOM 2553 C C   . LEU B 2 365 ? 118.417 117.658 104.181 1.00 101.60 ? 309 LEU R C   1 
ATOM 2554 O O   . LEU B 2 365 ? 119.052 116.770 104.758 1.00 101.60 ? 309 LEU R O   1 
ATOM 2555 C CB  . LEU B 2 365 ? 118.600 117.006 101.782 1.00 101.60 ? 309 LEU R CB  1 
ATOM 2556 C CG  . LEU B 2 365 ? 118.229 115.903 100.784 1.00 101.60 ? 309 LEU R CG  1 
ATOM 2557 C CD1 . LEU B 2 365 ? 119.390 115.640 99.842  1.00 101.60 ? 309 LEU R CD1 1 
ATOM 2558 C CD2 . LEU B 2 365 ? 117.826 114.616 101.484 1.00 101.60 ? 309 LEU R CD2 1 
ATOM 2559 N N   . ASN B 2 366 ? 118.398 118.914 104.618 1.00 101.60 ? 310 ASN R N   1 
ATOM 2560 C CA  . ASN B 2 366 ? 119.213 119.329 105.755 1.00 101.60 ? 310 ASN R CA  1 
ATOM 2561 C C   . ASN B 2 366 ? 118.823 118.598 107.034 1.00 101.60 ? 310 ASN R C   1 
ATOM 2562 O O   . ASN B 2 366 ? 119.702 118.112 107.755 1.00 101.60 ? 310 ASN R O   1 
ATOM 2563 C CB  . ASN B 2 366 ? 119.111 120.839 105.970 1.00 101.60 ? 310 ASN R CB  1 
ATOM 2564 C CG  . ASN B 2 366 ? 120.112 121.612 105.141 1.00 101.60 ? 310 ASN R CG  1 
ATOM 2565 O OD1 . ASN B 2 366 ? 121.100 121.058 104.662 1.00 101.60 ? 310 ASN R OD1 1 
ATOM 2566 N ND2 . ASN B 2 366 ? 119.862 122.903 104.968 1.00 101.60 ? 310 ASN R ND2 1 
ATOM 2567 N N   . PRO B 2 367 ? 117.534 118.507 107.367 1.00 101.60 ? 311 PRO R N   1 
ATOM 2568 C CA  . PRO B 2 367 ? 117.172 117.831 108.623 1.00 101.60 ? 311 PRO R CA  1 
ATOM 2569 C C   . PRO B 2 367 ? 117.697 116.410 108.714 1.00 101.60 ? 311 PRO R C   1 
ATOM 2570 O O   . PRO B 2 367 ? 118.143 115.989 109.788 1.00 101.60 ? 311 PRO R O   1 
ATOM 2571 C CB  . PRO B 2 367 ? 115.638 117.872 108.613 1.00 101.60 ? 311 PRO R CB  1 
ATOM 2572 C CG  . PRO B 2 367 ? 115.289 119.000 107.721 1.00 101.60 ? 311 PRO R CG  1 
ATOM 2573 C CD  . PRO B 2 367 ? 116.360 119.072 106.683 1.00 101.60 ? 311 PRO R CD  1 
ATOM 2574 N N   . LEU B 2 368 ? 117.665 115.653 107.616 1.00 101.60 ? 312 LEU R N   1 
ATOM 2575 C CA  . LEU B 2 368 ? 118.191 114.294 107.651 1.00 101.60 ? 312 LEU R CA  1 
ATOM 2576 C C   . LEU B 2 368 ? 119.713 114.287 107.674 1.00 101.60 ? 312 LEU R C   1 
ATOM 2577 O O   . LEU B 2 368 ? 120.322 113.516 108.423 1.00 101.60 ? 312 LEU R O   1 
ATOM 2578 C CB  . LEU B 2 368 ? 117.686 113.494 106.450 1.00 101.60 ? 312 LEU R CB  1 
ATOM 2579 C CG  . LEU B 2 368 ? 116.235 113.716 106.029 1.00 101.60 ? 312 LEU R CG  1 
ATOM 2580 C CD1 . LEU B 2 368 ? 115.847 112.730 104.942 1.00 101.60 ? 312 LEU R CD1 1 
ATOM 2581 C CD2 . LEU B 2 368 ? 115.303 113.594 107.221 1.00 101.60 ? 312 LEU R CD2 1 
ATOM 2582 N N   . ILE B 2 369 ? 120.341 115.138 106.864 1.00 101.60 ? 313 ILE R N   1 
ATOM 2583 C CA  . ILE B 2 369 ? 121.793 115.100 106.730 1.00 101.60 ? 313 ILE R CA  1 
ATOM 2584 C C   . ILE B 2 369 ? 122.468 115.507 108.032 1.00 101.60 ? 313 ILE R C   1 
ATOM 2585 O O   . ILE B 2 369 ? 123.439 114.876 108.465 1.00 101.60 ? 313 ILE R O   1 
ATOM 2586 C CB  . ILE B 2 369 ? 122.237 115.996 105.561 1.00 101.60 ? 313 ILE R CB  1 
ATOM 2587 C CG1 . ILE B 2 369 ? 121.795 115.395 104.223 1.00 101.60 ? 313 ILE R CG1 1 
ATOM 2588 C CG2 . ILE B 2 369 ? 123.737 116.193 105.592 1.00 101.60 ? 313 ILE R CG2 1 
ATOM 2589 C CD1 . ILE B 2 369 ? 122.466 114.080 103.867 1.00 101.60 ? 313 ILE R CD1 1 
ATOM 2590 N N   . TYR B 2 370 ? 121.975 116.563 108.677 1.00 101.60 ? 314 TYR R N   1 
ATOM 2591 C CA  . TYR B 2 370 ? 122.667 117.129 109.828 1.00 101.60 ? 314 TYR R CA  1 
ATOM 2592 C C   . TYR B 2 370 ? 122.132 116.621 111.160 1.00 101.60 ? 314 TYR R C   1 
ATOM 2593 O O   . TYR B 2 370 ? 122.920 116.254 112.038 1.00 101.60 ? 314 TYR R O   1 
ATOM 2594 C CB  . TYR B 2 370 ? 122.574 118.655 109.792 1.00 101.60 ? 314 TYR R CB  1 
ATOM 2595 C CG  . TYR B 2 370 ? 123.506 119.287 108.790 1.00 101.60 ? 314 TYR R CG  1 
ATOM 2596 C CD1 . TYR B 2 370 ? 124.810 119.601 109.131 1.00 101.60 ? 314 TYR R CD1 1 
ATOM 2597 C CD2 . TYR B 2 370 ? 123.082 119.565 107.502 1.00 101.60 ? 314 TYR R CD2 1 
ATOM 2598 C CE1 . TYR B 2 370 ? 125.665 120.174 108.219 1.00 101.60 ? 314 TYR R CE1 1 
ATOM 2599 C CE2 . TYR B 2 370 ? 123.929 120.139 106.583 1.00 101.60 ? 314 TYR R CE2 1 
ATOM 2600 C CZ  . TYR B 2 370 ? 125.220 120.440 106.946 1.00 101.60 ? 314 TYR R CZ  1 
ATOM 2601 O OH  . TYR B 2 370 ? 126.068 121.015 106.031 1.00 101.60 ? 314 TYR R OH  1 
ATOM 2602 N N   . ALA B 2 371 ? 120.814 116.584 111.337 1.00 101.60 ? 315 ALA R N   1 
ATOM 2603 C CA  . ALA B 2 371 ? 120.222 116.313 112.640 1.00 101.60 ? 315 ALA R CA  1 
ATOM 2604 C C   . ALA B 2 371 ? 119.781 114.870 112.817 1.00 101.60 ? 315 ALA R C   1 
ATOM 2605 O O   . ALA B 2 371 ? 120.254 114.189 113.731 1.00 101.60 ? 315 ALA R O   1 
ATOM 2606 C CB  . ALA B 2 371 ? 119.025 117.244 112.867 1.00 101.60 ? 315 ALA R CB  1 
ATOM 2607 N N   . PHE B 2 372 ? 118.890 114.373 111.961 1.00 101.60 ? 316 PHE R N   1 
ATOM 2608 C CA  . PHE B 2 372 ? 118.307 113.057 112.193 1.00 101.60 ? 316 PHE R CA  1 
ATOM 2609 C C   . PHE B 2 372 ? 119.288 111.919 111.970 1.00 101.60 ? 316 PHE R C   1 
ATOM 2610 O O   . PHE B 2 372 ? 118.961 110.778 112.309 1.00 101.60 ? 316 PHE R O   1 
ATOM 2611 C CB  . PHE B 2 372 ? 117.082 112.858 111.301 1.00 101.60 ? 316 PHE R CB  1 
ATOM 2612 C CG  . PHE B 2 372 ? 115.854 113.568 111.791 1.00 101.60 ? 316 PHE R CG  1 
ATOM 2613 C CD1 . PHE B 2 372 ? 115.307 113.262 113.023 1.00 101.60 ? 316 PHE R CD1 1 
ATOM 2614 C CD2 . PHE B 2 372 ? 115.246 114.537 111.017 1.00 101.60 ? 316 PHE R CD2 1 
ATOM 2615 C CE1 . PHE B 2 372 ? 114.181 113.912 113.473 1.00 101.60 ? 316 PHE R CE1 1 
ATOM 2616 C CE2 . PHE B 2 372 ? 114.118 115.188 111.464 1.00 101.60 ? 316 PHE R CE2 1 
ATOM 2617 C CZ  . PHE B 2 372 ? 113.586 114.875 112.693 1.00 101.60 ? 316 PHE R CZ  1 
ATOM 2618 N N   . ILE B 2 373 ? 120.473 112.183 111.410 1.00 101.60 ? 317 ILE R N   1 
ATOM 2619 C CA  . ILE B 2 373 ? 121.469 111.133 111.240 1.00 101.60 ? 317 ILE R CA  1 
ATOM 2620 C C   . ILE B 2 373 ? 122.183 110.804 112.540 1.00 101.60 ? 317 ILE R C   1 
ATOM 2621 O O   . ILE B 2 373 ? 122.992 109.868 112.572 1.00 101.60 ? 317 ILE R O   1 
ATOM 2622 C CB  . ILE B 2 373 ? 122.502 111.526 110.165 1.00 101.60 ? 317 ILE R CB  1 
ATOM 2623 C CG1 . ILE B 2 373 ? 123.280 110.294 109.704 1.00 101.60 ? 317 ILE R CG1 1 
ATOM 2624 C CG2 . ILE B 2 373 ? 123.454 112.585 110.696 1.00 101.60 ? 317 ILE R CG2 1 
ATOM 2625 C CD1 . ILE B 2 373 ? 123.741 110.375 108.269 1.00 101.60 ? 317 ILE R CD1 1 
ATOM 2626 N N   . GLY B 2 374 ? 121.910 111.538 113.608 1.00 101.60 ? 318 GLY R N   1 
ATOM 2627 C CA  . GLY B 2 374 ? 122.527 111.291 114.903 1.00 101.60 ? 318 GLY R CA  1 
ATOM 2628 C C   . GLY B 2 374 ? 121.533 110.658 115.856 1.00 101.60 ? 318 GLY R C   1 
ATOM 2629 O O   . GLY B 2 374 ? 120.341 110.962 115.811 1.00 101.60 ? 318 GLY R O   1 
ATOM 2630 N N   . GLN B 2 375 ? 122.036 109.779 116.721 1.00 93.30  ? 319 GLN R N   1 
ATOM 2631 C CA  . GLN B 2 375 ? 121.151 109.032 117.608 1.00 93.30  ? 319 GLN R CA  1 
ATOM 2632 C C   . GLN B 2 375 ? 120.447 109.941 118.607 1.00 93.30  ? 319 GLN R C   1 
ATOM 2633 O O   . GLN B 2 375 ? 119.352 109.608 119.075 1.00 93.30  ? 319 GLN R O   1 
ATOM 2634 C CB  . GLN B 2 375 ? 121.944 107.953 118.342 1.00 93.30  ? 319 GLN R CB  1 
ATOM 2635 C CG  . GLN B 2 375 ? 121.076 106.943 119.076 1.00 93.30  ? 319 GLN R CG  1 
ATOM 2636 C CD  . GLN B 2 375 ? 121.534 105.508 118.877 1.00 93.30  ? 319 GLN R CD  1 
ATOM 2637 O OE1 . GLN B 2 375 ? 122.417 105.227 118.066 1.00 93.30  ? 319 GLN R OE1 1 
ATOM 2638 N NE2 . GLN B 2 375 ? 120.931 104.589 119.621 1.00 93.30  ? 319 GLN R NE2 1 
ATOM 2639 N N   . LYS B 2 376 ? 121.049 111.081 118.950 1.00 101.60 ? 320 LYS R N   1 
ATOM 2640 C CA  . LYS B 2 376 ? 120.457 111.941 119.969 1.00 101.60 ? 320 LYS R CA  1 
ATOM 2641 C C   . LYS B 2 376 ? 119.073 112.419 119.549 1.00 101.60 ? 320 LYS R C   1 
ATOM 2642 O O   . LYS B 2 376 ? 118.120 112.363 120.334 1.00 101.60 ? 320 LYS R O   1 
ATOM 2643 C CB  . LYS B 2 376 ? 121.365 113.127 120.255 1.00 30.00  ? 320 LYS R CB  1 
ATOM 2644 N N   . PHE B 2 377 ? 118.940 112.893 118.310 1.00 101.60 ? 321 PHE R N   1 
ATOM 2645 C CA  . PHE B 2 377 ? 117.657 113.434 117.879 1.00 101.60 ? 321 PHE R CA  1 
ATOM 2646 C C   . PHE B 2 377 ? 116.616 112.338 117.713 1.00 101.60 ? 321 PHE R C   1 
ATOM 2647 O O   . PHE B 2 377 ? 115.440 112.548 118.019 1.00 101.60 ? 321 PHE R O   1 
ATOM 2648 C CB  . PHE B 2 377 ? 117.820 114.224 116.584 1.00 101.60 ? 321 PHE R CB  1 
ATOM 2649 C CG  . PHE B 2 377 ? 118.221 115.647 116.805 1.00 101.60 ? 321 PHE R CG  1 
ATOM 2650 C CD1 . PHE B 2 377 ? 119.348 115.953 117.545 1.00 101.60 ? 321 PHE R CD1 1 
ATOM 2651 C CD2 . PHE B 2 377 ? 117.461 116.681 116.294 1.00 101.60 ? 321 PHE R CD2 1 
ATOM 2652 C CE1 . PHE B 2 377 ? 119.718 117.262 117.758 1.00 101.60 ? 321 PHE R CE1 1 
ATOM 2653 C CE2 . PHE B 2 377 ? 117.826 117.992 116.504 1.00 101.60 ? 321 PHE R CE2 1 
ATOM 2654 C CZ  . PHE B 2 377 ? 118.955 118.283 117.239 1.00 101.60 ? 321 PHE R CZ  1 
ATOM 2655 N N   . ARG B 2 378 ? 117.018 111.166 117.224 1.00 101.60 ? 322 ARG R N   1 
ATOM 2656 C CA  . ARG B 2 378 ? 116.067 110.064 117.140 1.00 101.60 ? 322 ARG R CA  1 
ATOM 2657 C C   . ARG B 2 378 ? 115.565 109.679 118.524 1.00 101.60 ? 322 ARG R C   1 
ATOM 2658 O O   . ARG B 2 378 ? 114.361 109.467 118.721 1.00 101.60 ? 322 ARG R O   1 
ATOM 2659 C CB  . ARG B 2 378 ? 116.712 108.865 116.450 1.00 101.60 ? 322 ARG R CB  1 
ATOM 2660 C CG  . ARG B 2 378 ? 116.809 109.006 114.944 1.00 101.60 ? 322 ARG R CG  1 
ATOM 2661 C CD  . ARG B 2 378 ? 117.476 107.799 114.321 1.00 101.60 ? 322 ARG R CD  1 
ATOM 2662 N NE  . ARG B 2 378 ? 118.929 107.910 114.367 1.00 101.60 ? 322 ARG R NE  1 
ATOM 2663 C CZ  . ARG B 2 378 ? 119.743 107.024 114.926 1.00 101.60 ? 322 ARG R CZ  1 
ATOM 2664 N NH1 . ARG B 2 378 ? 119.287 105.916 115.488 1.00 101.60 ? 322 ARG R NH1 1 
ATOM 2665 N NH2 . ARG B 2 378 ? 121.052 107.256 114.921 1.00 101.60 ? 322 ARG R NH2 1 
ATOM 2666 N N   . HIS B 2 379 ? 116.472 109.600 119.498 1.00 101.60 ? 323 HIS R N   1 
ATOM 2667 C CA  . HIS B 2 379 ? 116.064 109.281 120.860 1.00 101.60 ? 323 HIS R CA  1 
ATOM 2668 C C   . HIS B 2 379 ? 115.130 110.349 121.414 1.00 101.60 ? 323 HIS R C   1 
ATOM 2669 O O   . HIS B 2 379 ? 114.122 110.030 122.054 1.00 101.60 ? 323 HIS R O   1 
ATOM 2670 C CB  . HIS B 2 379 ? 117.298 109.130 121.747 1.00 101.60 ? 323 HIS R CB  1 
ATOM 2671 C CG  . HIS B 2 379 ? 116.997 108.620 123.121 1.00 101.60 ? 323 HIS R CG  1 
ATOM 2672 N ND1 . HIS B 2 379 ? 116.583 107.328 123.360 1.00 101.60 ? 323 HIS R ND1 1 
ATOM 2673 C CD2 . HIS B 2 379 ? 117.048 109.229 124.329 1.00 101.60 ? 323 HIS R CD2 1 
ATOM 2674 C CE1 . HIS B 2 379 ? 116.393 107.162 124.657 1.00 101.60 ? 323 HIS R CE1 1 
ATOM 2675 N NE2 . HIS B 2 379 ? 116.668 108.301 125.267 1.00 101.60 ? 323 HIS R NE2 1 
ATOM 2676 N N   . GLY B 2 380 ? 115.447 111.622 121.175 1.00 101.60 ? 324 GLY R N   1 
ATOM 2677 C CA  . GLY B 2 380 ? 114.581 112.686 121.652 1.00 101.60 ? 324 GLY R CA  1 
ATOM 2678 C C   . GLY B 2 380 ? 113.202 112.628 121.029 1.00 101.60 ? 324 GLY R C   1 
ATOM 2679 O O   . GLY B 2 380 ? 112.192 112.787 121.717 1.00 101.60 ? 324 GLY R O   1 
ATOM 2680 N N   . LEU B 2 381 ? 113.140 112.392 119.718 1.00 101.60 ? 325 LEU R N   1 
ATOM 2681 C CA  . LEU B 2 381 ? 111.851 112.286 119.045 1.00 101.60 ? 325 LEU R CA  1 
ATOM 2682 C C   . LEU B 2 381 ? 111.037 111.127 119.601 1.00 101.60 ? 325 LEU R C   1 
ATOM 2683 O O   . LEU B 2 381 ? 109.837 111.274 119.860 1.00 101.60 ? 325 LEU R O   1 
ATOM 2684 C CB  . LEU B 2 381 ? 112.060 112.120 117.541 1.00 101.60 ? 325 LEU R CB  1 
ATOM 2685 C CG  . LEU B 2 381 ? 110.802 112.236 116.682 1.00 101.60 ? 325 LEU R CG  1 
ATOM 2686 C CD1 . LEU B 2 381 ? 110.377 113.685 116.549 1.00 101.60 ? 325 LEU R CD1 1 
ATOM 2687 C CD2 . LEU B 2 381 ? 111.037 111.618 115.315 1.00 101.60 ? 325 LEU R CD2 1 
ATOM 2688 N N   . LEU B 2 382 ? 111.669 109.969 119.800 1.00 101.60 ? 326 LEU R N   1 
ATOM 2689 C CA  . LEU B 2 382 ? 110.941 108.839 120.366 1.00 101.60 ? 326 LEU R CA  1 
ATOM 2690 C C   . LEU B 2 382 ? 110.441 109.160 121.769 1.00 101.60 ? 326 LEU R C   1 
ATOM 2691 O O   . LEU B 2 382 ? 109.303 108.829 122.118 1.00 101.60 ? 326 LEU R O   1 
ATOM 2692 C CB  . LEU B 2 382 ? 111.818 107.596 120.384 1.00 30.00  ? 326 LEU R CB  1 
ATOM 2693 N N   . LYS B 2 383 ? 111.273 109.812 122.584 1.00 101.60 ? 327 LYS R N   1 
ATOM 2694 C CA  . LYS B 2 383 ? 110.861 110.154 123.941 1.00 101.60 ? 327 LYS R CA  1 
ATOM 2695 C C   . LYS B 2 383 ? 109.683 111.121 123.934 1.00 101.60 ? 327 LYS R C   1 
ATOM 2696 O O   . LYS B 2 383 ? 108.760 110.995 124.746 1.00 101.60 ? 327 LYS R O   1 
ATOM 2697 C CB  . LYS B 2 383 ? 112.042 110.750 124.709 1.00 101.60 ? 327 LYS R CB  1 
ATOM 2698 C CG  . LYS B 2 383 ? 111.744 111.070 126.168 1.00 101.60 ? 327 LYS R CG  1 
ATOM 2699 C CD  . LYS B 2 383 ? 112.868 111.865 126.821 1.00 101.60 ? 327 LYS R CD  1 
ATOM 2700 C CE  . LYS B 2 383 ? 114.219 111.179 126.671 1.00 101.60 ? 327 LYS R CE  1 
ATOM 2701 N NZ  . LYS B 2 383 ? 114.170 109.740 127.048 1.00 101.60 ? 327 LYS R NZ  1 
ATOM 2702 N N   . ILE B 2 384 ? 109.699 112.099 123.026 1.00 101.60 ? 328 ILE R N   1 
ATOM 2703 C CA  . ILE B 2 384 ? 108.625 113.087 122.977 1.00 101.60 ? 328 ILE R CA  1 
ATOM 2704 C C   . ILE B 2 384 ? 107.295 112.432 122.637 1.00 101.60 ? 328 ILE R C   1 
ATOM 2705 O O   . ILE B 2 384 ? 106.230 112.964 122.974 1.00 101.60 ? 328 ILE R O   1 
ATOM 2706 C CB  . ILE B 2 384 ? 108.974 114.199 121.966 1.00 101.60 ? 328 ILE R CB  1 
ATOM 2707 C CG1 . ILE B 2 384 ? 110.112 115.084 122.488 1.00 101.60 ? 328 ILE R CG1 1 
ATOM 2708 C CG2 . ILE B 2 384 ? 107.749 115.045 121.657 1.00 101.60 ? 328 ILE R CG2 1 
ATOM 2709 C CD1 . ILE B 2 384 ? 109.940 115.568 123.912 1.00 101.60 ? 328 ILE R CD1 1 
ATOM 2710 N N   . LEU B 2 385 ? 107.324 111.272 121.981 1.00 101.60 ? 329 LEU R N   1 
ATOM 2711 C CA  . LEU B 2 385 ? 106.091 110.656 121.507 1.00 101.60 ? 329 LEU R CA  1 
ATOM 2712 C C   . LEU B 2 385 ? 105.148 110.274 122.640 1.00 101.60 ? 329 LEU R C   1 
ATOM 2713 O O   . LEU B 2 385 ? 103.965 110.027 122.379 1.00 101.60 ? 329 LEU R O   1 
ATOM 2714 C CB  . LEU B 2 385 ? 106.422 109.422 120.668 1.00 101.60 ? 329 LEU R CB  1 
ATOM 2715 C CG  . LEU B 2 385 ? 106.974 109.705 119.268 1.00 101.60 ? 329 LEU R CG  1 
ATOM 2716 C CD1 . LEU B 2 385 ? 107.392 108.412 118.587 1.00 101.60 ? 329 LEU R CD1 1 
ATOM 2717 C CD2 . LEU B 2 385 ? 105.960 110.455 118.417 1.00 101.60 ? 329 LEU R CD2 1 
ATOM 2718 N N   . ALA B 2 386 ? 105.629 110.221 123.878 1.00 101.60 ? 330 ALA R N   1 
ATOM 2719 C CA  . ALA B 2 386 ? 104.774 109.901 125.015 1.00 101.60 ? 330 ALA R CA  1 
ATOM 2720 C C   . ALA B 2 386 ? 103.736 110.995 125.238 1.00 101.60 ? 330 ALA R C   1 
ATOM 2721 O O   . ALA B 2 386 ? 102.785 111.129 124.467 1.00 101.60 ? 330 ALA R O   1 
ATOM 2722 C CB  . ALA B 2 386 ? 105.609 109.700 126.267 1.00 101.60 ? 330 ALA R CB  1 
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