data_8XWA
# 
_entry.id   8XWA 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XWA         pdb_00008xwa 10.2210/pdb8xwa/pdb 
WWPDB D_1300044347 ?            ?                   
EMDB  EMD-38732    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-15 ? 
2 'Structure model' 1 1 2025-04-09 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.journal_volume'          
7  2 'Structure model' '_citation.page_first'              
8  2 'Structure model' '_citation.page_last'               
9  2 'Structure model' '_citation.pdbx_database_id_DOI'    
10 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 2 'Structure model' '_citation.title'                   
12 2 'Structure model' '_citation.year'                    
13 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XWA 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of CXCR2 bound to CXCL1 (Ligand-receptor focused map)' 
_pdbx_database_related.db_id          EMD-38732 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 arshukla@iitk.ac.in       Arun  Shukla K 'principal investigator/group leader' 0000-0003-2910-8288 
3 nureki@bs.s.u-tokyo.ac.jp Osamu Nureki ? 'principal investigator/group leader' 0000-0003-1813-7008 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Sano, F.K.'   1 0000-0002-8965-788X 
'Saha, S.'     2 0000-0002-0036-4969 
'Sharma, S.'   3 0009-0005-9109-9054 
'Ganguly, M.'  4 0009-0007-6165-3063 
'Shihoya, W.'  5 0000-0003-4813-5740 
'Nureki, O.'   6 0000-0003-1813-7008 
'Shukla, A.K.' 7 0000-0003-2910-8288 
'Banerjee, R.' 8 0000-0002-7751-2317 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mol.Cell 
_citation.journal_id_ASTM           MOCEFL 
_citation.journal_id_CSD            2168 
_citation.journal_id_ISSN           1097-2765 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            85 
_citation.language                  ? 
_citation.page_first                976 
_citation.page_last                 988.e9 
_citation.title                     
'Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.molcel.2025.01.024 
_citation.pdbx_database_id_PubMed   39978339 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Saha, S.'        1  ? 
primary 'Sano, F.K.'      2  ? 
primary 'Sharma, S.'      3  ? 
primary 'Ganguly, M.'     4  ? 
primary 'Mishra, S.'      5  ? 
primary 'Dalal, A.'       6  ? 
primary 'Akasaka, H.'     7  ? 
primary 'Kobayashi, T.A.' 8  ? 
primary 'Zaidi, N.'       9  ? 
primary 'Tiwari, D.'      10 ? 
primary 'Roy, N.'         11 ? 
primary 'Yadav, M.K.'     12 ? 
primary 'Banerjee, N.'    13 ? 
primary 'Saha, S.'        14 ? 
primary 'Mohapatra, S.'   15 ? 
primary 'Itoh, Y.'        16 ? 
primary 'Chevigne, A.'    17 ? 
primary 'Banerjee, R.'    18 ? 
primary 'Shihoya, W.'     19 ? 
primary 'Nureki, O.'      20 ? 
primary 'Shukla, A.K.'    21 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Growth-regulated alpha protein'  7877.215  2 ? ? ? ? 
2 polymer man 'C-X-C chemokine receptor type 2' 46699.609 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'C-X-C motif chemokine 1,GRO-alpha(1-73),Melanoma growth stimulatory activity,MGSA,Neutrophil-activating protein 3,NAP-3' 
2 CXC-R2,CXCR-2                                                                                                             
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN 
ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN D,E ? 
2 'polypeptide(L)' no no 
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
R   ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   SER n 
1 3   VAL n 
1 4   ALA n 
1 5   THR n 
1 6   GLU n 
1 7   LEU n 
1 8   ARG n 
1 9   CYS n 
1 10  GLN n 
1 11  CYS n 
1 12  LEU n 
1 13  GLN n 
1 14  THR n 
1 15  LEU n 
1 16  GLN n 
1 17  GLY n 
1 18  ILE n 
1 19  HIS n 
1 20  PRO n 
1 21  LYS n 
1 22  ASN n 
1 23  ILE n 
1 24  GLN n 
1 25  SER n 
1 26  VAL n 
1 27  ASN n 
1 28  VAL n 
1 29  LYS n 
1 30  SER n 
1 31  PRO n 
1 32  GLY n 
1 33  PRO n 
1 34  HIS n 
1 35  CYS n 
1 36  ALA n 
1 37  GLN n 
1 38  THR n 
1 39  GLU n 
1 40  VAL n 
1 41  ILE n 
1 42  ALA n 
1 43  THR n 
1 44  LEU n 
1 45  LYS n 
1 46  ASN n 
1 47  GLY n 
1 48  ARG n 
1 49  LYS n 
1 50  ALA n 
1 51  CYS n 
1 52  LEU n 
1 53  ASN n 
1 54  PRO n 
1 55  ALA n 
1 56  SER n 
1 57  PRO n 
1 58  ILE n 
1 59  VAL n 
1 60  LYS n 
1 61  LYS n 
1 62  ILE n 
1 63  ILE n 
1 64  GLU n 
1 65  LYS n 
1 66  MET n 
1 67  LEU n 
1 68  ASN n 
1 69  SER n 
1 70  ASP n 
1 71  LYS n 
1 72  SER n 
1 73  ASN n 
2 1   MET n 
2 2   GLY n 
2 3   LYS n 
2 4   THR n 
2 5   ILE n 
2 6   ILE n 
2 7   ALA n 
2 8   LEU n 
2 9   SER n 
2 10  TYR n 
2 11  ILE n 
2 12  PHE n 
2 13  CYS n 
2 14  LEU n 
2 15  VAL n 
2 16  PHE n 
2 17  ALA n 
2 18  ASP n 
2 19  TYR n 
2 20  LYS n 
2 21  ASP n 
2 22  ASP n 
2 23  ASP n 
2 24  ASP n 
2 25  ALA n 
2 26  ALA n 
2 27  ASN n 
2 28  PHE n 
2 29  THR n 
2 30  PRO n 
2 31  VAL n 
2 32  ASN n 
2 33  GLY n 
2 34  SER n 
2 35  SER n 
2 36  GLY n 
2 37  ASN n 
2 38  GLN n 
2 39  SER n 
2 40  VAL n 
2 41  ARG n 
2 42  LEU n 
2 43  VAL n 
2 44  THR n 
2 45  SER n 
2 46  SER n 
2 47  SER n 
2 48  LEU n 
2 49  GLU n 
2 50  VAL n 
2 51  LEU n 
2 52  PHE n 
2 53  GLN n 
2 54  GLY n 
2 55  PRO n 
2 56  GLY n 
2 57  SER n 
2 58  GLU n 
2 59  ASP n 
2 60  PHE n 
2 61  ASN n 
2 62  MET n 
2 63  GLU n 
2 64  SER n 
2 65  ASP n 
2 66  SER n 
2 67  PHE n 
2 68  GLU n 
2 69  ASP n 
2 70  PHE n 
2 71  TRP n 
2 72  LYS n 
2 73  GLY n 
2 74  GLU n 
2 75  ASP n 
2 76  LEU n 
2 77  SER n 
2 78  ASN n 
2 79  TYR n 
2 80  SER n 
2 81  TYR n 
2 82  SER n 
2 83  SER n 
2 84  THR n 
2 85  LEU n 
2 86  PRO n 
2 87  PRO n 
2 88  PHE n 
2 89  LEU n 
2 90  LEU n 
2 91  ASP n 
2 92  ALA n 
2 93  ALA n 
2 94  PRO n 
2 95  CYS n 
2 96  GLU n 
2 97  PRO n 
2 98  GLU n 
2 99  SER n 
2 100 LEU n 
2 101 GLU n 
2 102 ILE n 
2 103 ASN n 
2 104 LYS n 
2 105 TYR n 
2 106 PHE n 
2 107 VAL n 
2 108 VAL n 
2 109 ILE n 
2 110 ILE n 
2 111 TYR n 
2 112 ALA n 
2 113 LEU n 
2 114 VAL n 
2 115 PHE n 
2 116 LEU n 
2 117 LEU n 
2 118 SER n 
2 119 LEU n 
2 120 LEU n 
2 121 GLY n 
2 122 ASN n 
2 123 SER n 
2 124 LEU n 
2 125 VAL n 
2 126 MET n 
2 127 LEU n 
2 128 VAL n 
2 129 ILE n 
2 130 LEU n 
2 131 TYR n 
2 132 SER n 
2 133 ARG n 
2 134 VAL n 
2 135 GLY n 
2 136 ARG n 
2 137 SER n 
2 138 VAL n 
2 139 THR n 
2 140 ASP n 
2 141 VAL n 
2 142 TYR n 
2 143 LEU n 
2 144 LEU n 
2 145 ASN n 
2 146 LEU n 
2 147 ALA n 
2 148 LEU n 
2 149 ALA n 
2 150 ASP n 
2 151 LEU n 
2 152 LEU n 
2 153 PHE n 
2 154 ALA n 
2 155 LEU n 
2 156 THR n 
2 157 LEU n 
2 158 PRO n 
2 159 ILE n 
2 160 TRP n 
2 161 ALA n 
2 162 ALA n 
2 163 SER n 
2 164 LYS n 
2 165 VAL n 
2 166 ASN n 
2 167 GLY n 
2 168 TRP n 
2 169 ILE n 
2 170 PHE n 
2 171 GLY n 
2 172 THR n 
2 173 PHE n 
2 174 LEU n 
2 175 CYS n 
2 176 LYS n 
2 177 VAL n 
2 178 VAL n 
2 179 SER n 
2 180 LEU n 
2 181 LEU n 
2 182 LYS n 
2 183 GLU n 
2 184 VAL n 
2 185 ASN n 
2 186 PHE n 
2 187 TYR n 
2 188 SER n 
2 189 GLY n 
2 190 ILE n 
2 191 LEU n 
2 192 LEU n 
2 193 LEU n 
2 194 ALA n 
2 195 CYS n 
2 196 ILE n 
2 197 SER n 
2 198 VAL n 
2 199 ASP n 
2 200 ARG n 
2 201 TYR n 
2 202 LEU n 
2 203 ALA n 
2 204 ILE n 
2 205 VAL n 
2 206 HIS n 
2 207 ALA n 
2 208 THR n 
2 209 ARG n 
2 210 THR n 
2 211 LEU n 
2 212 THR n 
2 213 GLN n 
2 214 LYS n 
2 215 ARG n 
2 216 TYR n 
2 217 LEU n 
2 218 VAL n 
2 219 LYS n 
2 220 PHE n 
2 221 ILE n 
2 222 CYS n 
2 223 LEU n 
2 224 SER n 
2 225 ILE n 
2 226 TRP n 
2 227 GLY n 
2 228 LEU n 
2 229 SER n 
2 230 LEU n 
2 231 LEU n 
2 232 LEU n 
2 233 ALA n 
2 234 LEU n 
2 235 PRO n 
2 236 VAL n 
2 237 LEU n 
2 238 LEU n 
2 239 PHE n 
2 240 ARG n 
2 241 ARG n 
2 242 THR n 
2 243 VAL n 
2 244 TYR n 
2 245 SER n 
2 246 SER n 
2 247 ASN n 
2 248 VAL n 
2 249 SER n 
2 250 PRO n 
2 251 ALA n 
2 252 CYS n 
2 253 TYR n 
2 254 GLU n 
2 255 ASP n 
2 256 MET n 
2 257 GLY n 
2 258 ASN n 
2 259 ASN n 
2 260 THR n 
2 261 ALA n 
2 262 ASN n 
2 263 TRP n 
2 264 ARG n 
2 265 MET n 
2 266 LEU n 
2 267 LEU n 
2 268 ARG n 
2 269 ILE n 
2 270 LEU n 
2 271 PRO n 
2 272 GLN n 
2 273 SER n 
2 274 PHE n 
2 275 GLY n 
2 276 PHE n 
2 277 ILE n 
2 278 VAL n 
2 279 PRO n 
2 280 LEU n 
2 281 LEU n 
2 282 ILE n 
2 283 MET n 
2 284 LEU n 
2 285 PHE n 
2 286 CYS n 
2 287 TYR n 
2 288 GLY n 
2 289 PHE n 
2 290 THR n 
2 291 LEU n 
2 292 ARG n 
2 293 THR n 
2 294 LEU n 
2 295 PHE n 
2 296 LYS n 
2 297 ALA n 
2 298 HIS n 
2 299 MET n 
2 300 GLY n 
2 301 GLN n 
2 302 LYS n 
2 303 HIS n 
2 304 ARG n 
2 305 ALA n 
2 306 MET n 
2 307 ARG n 
2 308 VAL n 
2 309 ILE n 
2 310 PHE n 
2 311 ALA n 
2 312 VAL n 
2 313 VAL n 
2 314 LEU n 
2 315 ILE n 
2 316 PHE n 
2 317 LEU n 
2 318 LEU n 
2 319 CYS n 
2 320 TRP n 
2 321 LEU n 
2 322 PRO n 
2 323 TYR n 
2 324 ASN n 
2 325 LEU n 
2 326 VAL n 
2 327 LEU n 
2 328 LEU n 
2 329 ALA n 
2 330 ASP n 
2 331 THR n 
2 332 LEU n 
2 333 MET n 
2 334 ARG n 
2 335 THR n 
2 336 GLN n 
2 337 VAL n 
2 338 ILE n 
2 339 GLN n 
2 340 GLU n 
2 341 THR n 
2 342 CYS n 
2 343 GLU n 
2 344 ARG n 
2 345 ARG n 
2 346 ASN n 
2 347 HIS n 
2 348 ILE n 
2 349 ASP n 
2 350 ARG n 
2 351 ALA n 
2 352 LEU n 
2 353 ASP n 
2 354 ALA n 
2 355 THR n 
2 356 GLU n 
2 357 ILE n 
2 358 LEU n 
2 359 GLY n 
2 360 ILE n 
2 361 LEU n 
2 362 HIS n 
2 363 SER n 
2 364 CYS n 
2 365 LEU n 
2 366 ASN n 
2 367 PRO n 
2 368 LEU n 
2 369 ILE n 
2 370 TYR n 
2 371 ALA n 
2 372 PHE n 
2 373 ILE n 
2 374 GLY n 
2 375 GLN n 
2 376 LYS n 
2 377 PHE n 
2 378 ARG n 
2 379 HIS n 
2 380 GLY n 
2 381 LEU n 
2 382 LEU n 
2 383 LYS n 
2 384 ILE n 
2 385 LEU n 
2 386 ALA n 
2 387 ILE n 
2 388 HIS n 
2 389 GLY n 
2 390 LEU n 
2 391 ILE n 
2 392 SER n 
2 393 LYS n 
2 394 ASP n 
2 395 SER n 
2 396 LEU n 
2 397 PRO n 
2 398 LYS n 
2 399 ASP n 
2 400 SER n 
2 401 ARG n 
2 402 PRO n 
2 403 SER n 
2 404 PHE n 
2 405 VAL n 
2 406 GLY n 
2 407 SER n 
2 408 SER n 
2 409 SER n 
2 410 GLY n 
2 411 HIS n 
2 412 THR n 
2 413 SER n 
2 414 THR n 
2 415 THR n 
2 416 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 73  human ? CXCL1 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli'      562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 416 human ? CXCR2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA D . n 
A 1 2   SER 2   2   2   SER SER D . n 
A 1 3   VAL 3   3   3   VAL VAL D . n 
A 1 4   ALA 4   4   4   ALA ALA D . n 
A 1 5   THR 5   5   5   THR THR D . n 
A 1 6   GLU 6   6   6   GLU GLU D . n 
A 1 7   LEU 7   7   7   LEU LEU D . n 
A 1 8   ARG 8   8   8   ARG ARG D . n 
A 1 9   CYS 9   9   9   CYS CYS D . n 
A 1 10  GLN 10  10  10  GLN GLN D . n 
A 1 11  CYS 11  11  11  CYS CYS D . n 
A 1 12  LEU 12  12  12  LEU LEU D . n 
A 1 13  GLN 13  13  13  GLN GLN D . n 
A 1 14  THR 14  14  14  THR THR D . n 
A 1 15  LEU 15  15  15  LEU LEU D . n 
A 1 16  GLN 16  16  16  GLN GLN D . n 
A 1 17  GLY 17  17  17  GLY GLY D . n 
A 1 18  ILE 18  18  18  ILE ILE D . n 
A 1 19  HIS 19  19  19  HIS HIS D . n 
A 1 20  PRO 20  20  20  PRO PRO D . n 
A 1 21  LYS 21  21  21  LYS LYS D . n 
A 1 22  ASN 22  22  22  ASN ASN D . n 
A 1 23  ILE 23  23  23  ILE ILE D . n 
A 1 24  GLN 24  24  24  GLN GLN D . n 
A 1 25  SER 25  25  25  SER SER D . n 
A 1 26  VAL 26  26  26  VAL VAL D . n 
A 1 27  ASN 27  27  27  ASN ASN D . n 
A 1 28  VAL 28  28  28  VAL VAL D . n 
A 1 29  LYS 29  29  29  LYS LYS D . n 
A 1 30  SER 30  30  30  SER SER D . n 
A 1 31  PRO 31  31  31  PRO PRO D . n 
A 1 32  GLY 32  32  32  GLY GLY D . n 
A 1 33  PRO 33  33  33  PRO PRO D . n 
A 1 34  HIS 34  34  34  HIS HIS D . n 
A 1 35  CYS 35  35  35  CYS CYS D . n 
A 1 36  ALA 36  36  36  ALA ALA D . n 
A 1 37  GLN 37  37  37  GLN GLN D . n 
A 1 38  THR 38  38  38  THR THR D . n 
A 1 39  GLU 39  39  39  GLU GLU D . n 
A 1 40  VAL 40  40  40  VAL VAL D . n 
A 1 41  ILE 41  41  41  ILE ILE D . n 
A 1 42  ALA 42  42  42  ALA ALA D . n 
A 1 43  THR 43  43  43  THR THR D . n 
A 1 44  LEU 44  44  44  LEU LEU D . n 
A 1 45  LYS 45  45  45  LYS LYS D . n 
A 1 46  ASN 46  46  46  ASN ASN D . n 
A 1 47  GLY 47  47  47  GLY GLY D . n 
A 1 48  ARG 48  48  48  ARG ARG D . n 
A 1 49  LYS 49  49  49  LYS LYS D . n 
A 1 50  ALA 50  50  50  ALA ALA D . n 
A 1 51  CYS 51  51  51  CYS CYS D . n 
A 1 52  LEU 52  52  52  LEU LEU D . n 
A 1 53  ASN 53  53  53  ASN ASN D . n 
A 1 54  PRO 54  54  54  PRO PRO D . n 
A 1 55  ALA 55  55  55  ALA ALA D . n 
A 1 56  SER 56  56  56  SER SER D . n 
A 1 57  PRO 57  57  57  PRO PRO D . n 
A 1 58  ILE 58  58  58  ILE ILE D . n 
A 1 59  VAL 59  59  59  VAL VAL D . n 
A 1 60  LYS 60  60  60  LYS LYS D . n 
A 1 61  LYS 61  61  61  LYS LYS D . n 
A 1 62  ILE 62  62  62  ILE ILE D . n 
A 1 63  ILE 63  63  63  ILE ILE D . n 
A 1 64  GLU 64  64  64  GLU GLU D . n 
A 1 65  LYS 65  65  65  LYS LYS D . n 
A 1 66  MET 66  66  66  MET MET D . n 
A 1 67  LEU 67  67  67  LEU LEU D . n 
A 1 68  ASN 68  68  68  ASN ASN D . n 
A 1 69  SER 69  69  ?   ?   ?   D . n 
A 1 70  ASP 70  70  ?   ?   ?   D . n 
A 1 71  LYS 71  71  ?   ?   ?   D . n 
A 1 72  SER 72  72  ?   ?   ?   D . n 
A 1 73  ASN 73  73  ?   ?   ?   D . n 
B 1 1   ALA 1   1   ?   ?   ?   E . n 
B 1 2   SER 2   2   ?   ?   ?   E . n 
B 1 3   VAL 3   3   ?   ?   ?   E . n 
B 1 4   ALA 4   4   ?   ?   ?   E . n 
B 1 5   THR 5   5   ?   ?   ?   E . n 
B 1 6   GLU 6   6   ?   ?   ?   E . n 
B 1 7   LEU 7   7   ?   ?   ?   E . n 
B 1 8   ARG 8   8   ?   ?   ?   E . n 
B 1 9   CYS 9   9   9   CYS CYS E . n 
B 1 10  GLN 10  10  10  GLN GLN E . n 
B 1 11  CYS 11  11  11  CYS CYS E . n 
B 1 12  LEU 12  12  12  LEU LEU E . n 
B 1 13  GLN 13  13  13  GLN GLN E . n 
B 1 14  THR 14  14  14  THR THR E . n 
B 1 15  LEU 15  15  15  LEU LEU E . n 
B 1 16  GLN 16  16  16  GLN GLN E . n 
B 1 17  GLY 17  17  17  GLY GLY E . n 
B 1 18  ILE 18  18  18  ILE ILE E . n 
B 1 19  HIS 19  19  19  HIS HIS E . n 
B 1 20  PRO 20  20  20  PRO PRO E . n 
B 1 21  LYS 21  21  21  LYS LYS E . n 
B 1 22  ASN 22  22  22  ASN ASN E . n 
B 1 23  ILE 23  23  23  ILE ILE E . n 
B 1 24  GLN 24  24  24  GLN GLN E . n 
B 1 25  SER 25  25  25  SER SER E . n 
B 1 26  VAL 26  26  26  VAL VAL E . n 
B 1 27  ASN 27  27  27  ASN ASN E . n 
B 1 28  VAL 28  28  28  VAL VAL E . n 
B 1 29  LYS 29  29  29  LYS LYS E . n 
B 1 30  SER 30  30  30  SER SER E . n 
B 1 31  PRO 31  31  31  PRO PRO E . n 
B 1 32  GLY 32  32  32  GLY GLY E . n 
B 1 33  PRO 33  33  33  PRO PRO E . n 
B 1 34  HIS 34  34  34  HIS HIS E . n 
B 1 35  CYS 35  35  35  CYS CYS E . n 
B 1 36  ALA 36  36  36  ALA ALA E . n 
B 1 37  GLN 37  37  37  GLN GLN E . n 
B 1 38  THR 38  38  38  THR THR E . n 
B 1 39  GLU 39  39  39  GLU GLU E . n 
B 1 40  VAL 40  40  40  VAL VAL E . n 
B 1 41  ILE 41  41  41  ILE ILE E . n 
B 1 42  ALA 42  42  42  ALA ALA E . n 
B 1 43  THR 43  43  43  THR THR E . n 
B 1 44  LEU 44  44  44  LEU LEU E . n 
B 1 45  LYS 45  45  45  LYS LYS E . n 
B 1 46  ASN 46  46  46  ASN ASN E . n 
B 1 47  GLY 47  47  47  GLY GLY E . n 
B 1 48  ARG 48  48  48  ARG ARG E . n 
B 1 49  LYS 49  49  49  LYS LYS E . n 
B 1 50  ALA 50  50  50  ALA ALA E . n 
B 1 51  CYS 51  51  51  CYS CYS E . n 
B 1 52  LEU 52  52  52  LEU LEU E . n 
B 1 53  ASN 53  53  53  ASN ASN E . n 
B 1 54  PRO 54  54  54  PRO PRO E . n 
B 1 55  ALA 55  55  55  ALA ALA E . n 
B 1 56  SER 56  56  56  SER SER E . n 
B 1 57  PRO 57  57  57  PRO PRO E . n 
B 1 58  ILE 58  58  58  ILE ILE E . n 
B 1 59  VAL 59  59  59  VAL VAL E . n 
B 1 60  LYS 60  60  60  LYS LYS E . n 
B 1 61  LYS 61  61  61  LYS LYS E . n 
B 1 62  ILE 62  62  62  ILE ILE E . n 
B 1 63  ILE 63  63  63  ILE ILE E . n 
B 1 64  GLU 64  64  64  GLU GLU E . n 
B 1 65  LYS 65  65  65  LYS LYS E . n 
B 1 66  MET 66  66  66  MET MET E . n 
B 1 67  LEU 67  67  67  LEU LEU E . n 
B 1 68  ASN 68  68  68  ASN ASN E . n 
B 1 69  SER 69  69  69  SER SER E . n 
B 1 70  ASP 70  70  ?   ?   ?   E . n 
B 1 71  LYS 71  71  ?   ?   ?   E . n 
B 1 72  SER 72  72  ?   ?   ?   E . n 
B 1 73  ASN 73  73  ?   ?   ?   E . n 
C 2 1   MET 1   -55 ?   ?   ?   R . n 
C 2 2   GLY 2   -54 ?   ?   ?   R . n 
C 2 3   LYS 3   -53 ?   ?   ?   R . n 
C 2 4   THR 4   -52 ?   ?   ?   R . n 
C 2 5   ILE 5   -51 ?   ?   ?   R . n 
C 2 6   ILE 6   -50 ?   ?   ?   R . n 
C 2 7   ALA 7   -49 ?   ?   ?   R . n 
C 2 8   LEU 8   -48 ?   ?   ?   R . n 
C 2 9   SER 9   -47 ?   ?   ?   R . n 
C 2 10  TYR 10  -46 ?   ?   ?   R . n 
C 2 11  ILE 11  -45 ?   ?   ?   R . n 
C 2 12  PHE 12  -44 ?   ?   ?   R . n 
C 2 13  CYS 13  -43 ?   ?   ?   R . n 
C 2 14  LEU 14  -42 ?   ?   ?   R . n 
C 2 15  VAL 15  -41 ?   ?   ?   R . n 
C 2 16  PHE 16  -40 ?   ?   ?   R . n 
C 2 17  ALA 17  -39 ?   ?   ?   R . n 
C 2 18  ASP 18  -38 ?   ?   ?   R . n 
C 2 19  TYR 19  -37 ?   ?   ?   R . n 
C 2 20  LYS 20  -36 ?   ?   ?   R . n 
C 2 21  ASP 21  -35 ?   ?   ?   R . n 
C 2 22  ASP 22  -34 ?   ?   ?   R . n 
C 2 23  ASP 23  -33 ?   ?   ?   R . n 
C 2 24  ASP 24  -32 ?   ?   ?   R . n 
C 2 25  ALA 25  -31 ?   ?   ?   R . n 
C 2 26  ALA 26  -30 ?   ?   ?   R . n 
C 2 27  ASN 27  -29 ?   ?   ?   R . n 
C 2 28  PHE 28  -28 ?   ?   ?   R . n 
C 2 29  THR 29  -27 ?   ?   ?   R . n 
C 2 30  PRO 30  -26 ?   ?   ?   R . n 
C 2 31  VAL 31  -25 ?   ?   ?   R . n 
C 2 32  ASN 32  -24 ?   ?   ?   R . n 
C 2 33  GLY 33  -23 ?   ?   ?   R . n 
C 2 34  SER 34  -22 ?   ?   ?   R . n 
C 2 35  SER 35  -21 ?   ?   ?   R . n 
C 2 36  GLY 36  -20 ?   ?   ?   R . n 
C 2 37  ASN 37  -19 ?   ?   ?   R . n 
C 2 38  GLN 38  -18 ?   ?   ?   R . n 
C 2 39  SER 39  -17 ?   ?   ?   R . n 
C 2 40  VAL 40  -16 ?   ?   ?   R . n 
C 2 41  ARG 41  -15 ?   ?   ?   R . n 
C 2 42  LEU 42  -14 ?   ?   ?   R . n 
C 2 43  VAL 43  -13 ?   ?   ?   R . n 
C 2 44  THR 44  -12 ?   ?   ?   R . n 
C 2 45  SER 45  -11 ?   ?   ?   R . n 
C 2 46  SER 46  -10 ?   ?   ?   R . n 
C 2 47  SER 47  -9  ?   ?   ?   R . n 
C 2 48  LEU 48  -8  ?   ?   ?   R . n 
C 2 49  GLU 49  -7  ?   ?   ?   R . n 
C 2 50  VAL 50  -6  ?   ?   ?   R . n 
C 2 51  LEU 51  -5  ?   ?   ?   R . n 
C 2 52  PHE 52  -4  ?   ?   ?   R . n 
C 2 53  GLN 53  -3  ?   ?   ?   R . n 
C 2 54  GLY 54  -2  ?   ?   ?   R . n 
C 2 55  PRO 55  -1  ?   ?   ?   R . n 
C 2 56  GLY 56  0   ?   ?   ?   R . n 
C 2 57  SER 57  1   ?   ?   ?   R . n 
C 2 58  GLU 58  2   ?   ?   ?   R . n 
C 2 59  ASP 59  3   ?   ?   ?   R . n 
C 2 60  PHE 60  4   ?   ?   ?   R . n 
C 2 61  ASN 61  5   ?   ?   ?   R . n 
C 2 62  MET 62  6   ?   ?   ?   R . n 
C 2 63  GLU 63  7   ?   ?   ?   R . n 
C 2 64  SER 64  8   ?   ?   ?   R . n 
C 2 65  ASP 65  9   ?   ?   ?   R . n 
C 2 66  SER 66  10  ?   ?   ?   R . n 
C 2 67  PHE 67  11  ?   ?   ?   R . n 
C 2 68  GLU 68  12  ?   ?   ?   R . n 
C 2 69  ASP 69  13  ?   ?   ?   R . n 
C 2 70  PHE 70  14  ?   ?   ?   R . n 
C 2 71  TRP 71  15  ?   ?   ?   R . n 
C 2 72  LYS 72  16  ?   ?   ?   R . n 
C 2 73  GLY 73  17  ?   ?   ?   R . n 
C 2 74  GLU 74  18  ?   ?   ?   R . n 
C 2 75  ASP 75  19  ?   ?   ?   R . n 
C 2 76  LEU 76  20  ?   ?   ?   R . n 
C 2 77  SER 77  21  ?   ?   ?   R . n 
C 2 78  ASN 78  22  ?   ?   ?   R . n 
C 2 79  TYR 79  23  ?   ?   ?   R . n 
C 2 80  SER 80  24  ?   ?   ?   R . n 
C 2 81  TYR 81  25  ?   ?   ?   R . n 
C 2 82  SER 82  26  ?   ?   ?   R . n 
C 2 83  SER 83  27  ?   ?   ?   R . n 
C 2 84  THR 84  28  ?   ?   ?   R . n 
C 2 85  LEU 85  29  ?   ?   ?   R . n 
C 2 86  PRO 86  30  ?   ?   ?   R . n 
C 2 87  PRO 87  31  ?   ?   ?   R . n 
C 2 88  PHE 88  32  ?   ?   ?   R . n 
C 2 89  LEU 89  33  ?   ?   ?   R . n 
C 2 90  LEU 90  34  34  LEU LEU R . n 
C 2 91  ASP 91  35  35  ASP ASP R . n 
C 2 92  ALA 92  36  36  ALA ALA R . n 
C 2 93  ALA 93  37  37  ALA ALA R . n 
C 2 94  PRO 94  38  38  PRO PRO R . n 
C 2 95  CYS 95  39  39  CYS CYS R . n 
C 2 96  GLU 96  40  40  GLU GLU R . n 
C 2 97  PRO 97  41  41  PRO PRO R . n 
C 2 98  GLU 98  42  42  GLU GLU R . n 
C 2 99  SER 99  43  43  SER SER R . n 
C 2 100 LEU 100 44  44  LEU LEU R . n 
C 2 101 GLU 101 45  45  GLU GLU R . n 
C 2 102 ILE 102 46  46  ILE ILE R . n 
C 2 103 ASN 103 47  47  ASN ASN R . n 
C 2 104 LYS 104 48  48  LYS LYS R . n 
C 2 105 TYR 105 49  49  TYR TYR R . n 
C 2 106 PHE 106 50  50  PHE PHE R . n 
C 2 107 VAL 107 51  51  VAL VAL R . n 
C 2 108 VAL 108 52  52  VAL VAL R . n 
C 2 109 ILE 109 53  53  ILE ILE R . n 
C 2 110 ILE 110 54  54  ILE ILE R . n 
C 2 111 TYR 111 55  55  TYR TYR R . n 
C 2 112 ALA 112 56  56  ALA ALA R . n 
C 2 113 LEU 113 57  57  LEU LEU R . n 
C 2 114 VAL 114 58  58  VAL VAL R . n 
C 2 115 PHE 115 59  59  PHE PHE R . n 
C 2 116 LEU 116 60  60  LEU LEU R . n 
C 2 117 LEU 117 61  61  LEU LEU R . n 
C 2 118 SER 118 62  62  SER SER R . n 
C 2 119 LEU 119 63  63  LEU LEU R . n 
C 2 120 LEU 120 64  64  LEU LEU R . n 
C 2 121 GLY 121 65  65  GLY GLY R . n 
C 2 122 ASN 122 66  66  ASN ASN R . n 
C 2 123 SER 123 67  67  SER SER R . n 
C 2 124 LEU 124 68  68  LEU LEU R . n 
C 2 125 VAL 125 69  69  VAL VAL R . n 
C 2 126 MET 126 70  70  MET MET R . n 
C 2 127 LEU 127 71  71  LEU LEU R . n 
C 2 128 VAL 128 72  72  VAL VAL R . n 
C 2 129 ILE 129 73  73  ILE ILE R . n 
C 2 130 LEU 130 74  74  LEU LEU R . n 
C 2 131 TYR 131 75  75  TYR TYR R . n 
C 2 132 SER 132 76  76  SER SER R . n 
C 2 133 ARG 133 77  77  ARG ARG R . n 
C 2 134 VAL 134 78  78  VAL VAL R . n 
C 2 135 GLY 135 79  79  GLY GLY R . n 
C 2 136 ARG 136 80  80  ARG ARG R . n 
C 2 137 SER 137 81  81  SER SER R . n 
C 2 138 VAL 138 82  82  VAL VAL R . n 
C 2 139 THR 139 83  83  THR THR R . n 
C 2 140 ASP 140 84  84  ASP ASP R . n 
C 2 141 VAL 141 85  85  VAL VAL R . n 
C 2 142 TYR 142 86  86  TYR TYR R . n 
C 2 143 LEU 143 87  87  LEU LEU R . n 
C 2 144 LEU 144 88  88  LEU LEU R . n 
C 2 145 ASN 145 89  89  ASN ASN R . n 
C 2 146 LEU 146 90  90  LEU LEU R . n 
C 2 147 ALA 147 91  91  ALA ALA R . n 
C 2 148 LEU 148 92  92  LEU LEU R . n 
C 2 149 ALA 149 93  93  ALA ALA R . n 
C 2 150 ASP 150 94  94  ASP ASP R . n 
C 2 151 LEU 151 95  95  LEU LEU R . n 
C 2 152 LEU 152 96  96  LEU LEU R . n 
C 2 153 PHE 153 97  97  PHE PHE R . n 
C 2 154 ALA 154 98  98  ALA ALA R . n 
C 2 155 LEU 155 99  99  LEU LEU R . n 
C 2 156 THR 156 100 100 THR THR R . n 
C 2 157 LEU 157 101 101 LEU LEU R . n 
C 2 158 PRO 158 102 102 PRO PRO R . n 
C 2 159 ILE 159 103 103 ILE ILE R . n 
C 2 160 TRP 160 104 104 TRP TRP R . n 
C 2 161 ALA 161 105 105 ALA ALA R . n 
C 2 162 ALA 162 106 106 ALA ALA R . n 
C 2 163 SER 163 107 107 SER SER R . n 
C 2 164 LYS 164 108 108 LYS LYS R . n 
C 2 165 VAL 165 109 109 VAL VAL R . n 
C 2 166 ASN 166 110 110 ASN ASN R . n 
C 2 167 GLY 167 111 111 GLY GLY R . n 
C 2 168 TRP 168 112 112 TRP TRP R . n 
C 2 169 ILE 169 113 113 ILE ILE R . n 
C 2 170 PHE 170 114 114 PHE PHE R . n 
C 2 171 GLY 171 115 115 GLY GLY R . n 
C 2 172 THR 172 116 116 THR THR R . n 
C 2 173 PHE 173 117 117 PHE PHE R . n 
C 2 174 LEU 174 118 118 LEU LEU R . n 
C 2 175 CYS 175 119 119 CYS CYS R . n 
C 2 176 LYS 176 120 120 LYS LYS R . n 
C 2 177 VAL 177 121 121 VAL VAL R . n 
C 2 178 VAL 178 122 122 VAL VAL R . n 
C 2 179 SER 179 123 123 SER SER R . n 
C 2 180 LEU 180 124 124 LEU LEU R . n 
C 2 181 LEU 181 125 125 LEU LEU R . n 
C 2 182 LYS 182 126 126 LYS LYS R . n 
C 2 183 GLU 183 127 127 GLU GLU R . n 
C 2 184 VAL 184 128 128 VAL VAL R . n 
C 2 185 ASN 185 129 129 ASN ASN R . n 
C 2 186 PHE 186 130 130 PHE PHE R . n 
C 2 187 TYR 187 131 131 TYR TYR R . n 
C 2 188 SER 188 132 132 SER SER R . n 
C 2 189 GLY 189 133 133 GLY GLY R . n 
C 2 190 ILE 190 134 134 ILE ILE R . n 
C 2 191 LEU 191 135 135 LEU LEU R . n 
C 2 192 LEU 192 136 136 LEU LEU R . n 
C 2 193 LEU 193 137 137 LEU LEU R . n 
C 2 194 ALA 194 138 138 ALA ALA R . n 
C 2 195 CYS 195 139 139 CYS CYS R . n 
C 2 196 ILE 196 140 140 ILE ILE R . n 
C 2 197 SER 197 141 141 SER SER R . n 
C 2 198 VAL 198 142 142 VAL VAL R . n 
C 2 199 ASP 199 143 143 ASP ASP R . n 
C 2 200 ARG 200 144 144 ARG ARG R . n 
C 2 201 TYR 201 145 145 TYR TYR R . n 
C 2 202 LEU 202 146 146 LEU LEU R . n 
C 2 203 ALA 203 147 147 ALA ALA R . n 
C 2 204 ILE 204 148 148 ILE ILE R . n 
C 2 205 VAL 205 149 149 VAL VAL R . n 
C 2 206 HIS 206 150 150 HIS HIS R . n 
C 2 207 ALA 207 151 151 ALA ALA R . n 
C 2 208 THR 208 152 152 THR THR R . n 
C 2 209 ARG 209 153 153 ARG ARG R . n 
C 2 210 THR 210 154 154 THR THR R . n 
C 2 211 LEU 211 155 155 LEU LEU R . n 
C 2 212 THR 212 156 156 THR THR R . n 
C 2 213 GLN 213 157 157 GLN GLN R . n 
C 2 214 LYS 214 158 158 LYS LYS R . n 
C 2 215 ARG 215 159 159 ARG ARG R . n 
C 2 216 TYR 216 160 160 TYR TYR R . n 
C 2 217 LEU 217 161 161 LEU LEU R . n 
C 2 218 VAL 218 162 162 VAL VAL R . n 
C 2 219 LYS 219 163 163 LYS LYS R . n 
C 2 220 PHE 220 164 164 PHE PHE R . n 
C 2 221 ILE 221 165 165 ILE ILE R . n 
C 2 222 CYS 222 166 166 CYS CYS R . n 
C 2 223 LEU 223 167 167 LEU LEU R . n 
C 2 224 SER 224 168 168 SER SER R . n 
C 2 225 ILE 225 169 169 ILE ILE R . n 
C 2 226 TRP 226 170 170 TRP TRP R . n 
C 2 227 GLY 227 171 171 GLY GLY R . n 
C 2 228 LEU 228 172 172 LEU LEU R . n 
C 2 229 SER 229 173 173 SER SER R . n 
C 2 230 LEU 230 174 174 LEU LEU R . n 
C 2 231 LEU 231 175 175 LEU LEU R . n 
C 2 232 LEU 232 176 176 LEU LEU R . n 
C 2 233 ALA 233 177 177 ALA ALA R . n 
C 2 234 LEU 234 178 178 LEU LEU R . n 
C 2 235 PRO 235 179 179 PRO PRO R . n 
C 2 236 VAL 236 180 180 VAL VAL R . n 
C 2 237 LEU 237 181 181 LEU LEU R . n 
C 2 238 LEU 238 182 182 LEU LEU R . n 
C 2 239 PHE 239 183 183 PHE PHE R . n 
C 2 240 ARG 240 184 184 ARG ARG R . n 
C 2 241 ARG 241 185 185 ARG ARG R . n 
C 2 242 THR 242 186 186 THR THR R . n 
C 2 243 VAL 243 187 187 VAL VAL R . n 
C 2 244 TYR 244 188 188 TYR TYR R . n 
C 2 245 SER 245 189 189 SER SER R . n 
C 2 246 SER 246 190 190 SER SER R . n 
C 2 247 ASN 247 191 191 ASN ASN R . n 
C 2 248 VAL 248 192 192 VAL VAL R . n 
C 2 249 SER 249 193 193 SER SER R . n 
C 2 250 PRO 250 194 194 PRO PRO R . n 
C 2 251 ALA 251 195 195 ALA ALA R . n 
C 2 252 CYS 252 196 196 CYS CYS R . n 
C 2 253 TYR 253 197 197 TYR TYR R . n 
C 2 254 GLU 254 198 198 GLU GLU R . n 
C 2 255 ASP 255 199 199 ASP ASP R . n 
C 2 256 MET 256 200 200 MET MET R . n 
C 2 257 GLY 257 201 201 GLY GLY R . n 
C 2 258 ASN 258 202 202 ASN ASN R . n 
C 2 259 ASN 259 203 203 ASN ASN R . n 
C 2 260 THR 260 204 204 THR THR R . n 
C 2 261 ALA 261 205 205 ALA ALA R . n 
C 2 262 ASN 262 206 206 ASN ASN R . n 
C 2 263 TRP 263 207 207 TRP TRP R . n 
C 2 264 ARG 264 208 208 ARG ARG R . n 
C 2 265 MET 265 209 209 MET MET R . n 
C 2 266 LEU 266 210 210 LEU LEU R . n 
C 2 267 LEU 267 211 211 LEU LEU R . n 
C 2 268 ARG 268 212 212 ARG ARG R . n 
C 2 269 ILE 269 213 213 ILE ILE R . n 
C 2 270 LEU 270 214 214 LEU LEU R . n 
C 2 271 PRO 271 215 215 PRO PRO R . n 
C 2 272 GLN 272 216 216 GLN GLN R . n 
C 2 273 SER 273 217 217 SER SER R . n 
C 2 274 PHE 274 218 218 PHE PHE R . n 
C 2 275 GLY 275 219 219 GLY GLY R . n 
C 2 276 PHE 276 220 220 PHE PHE R . n 
C 2 277 ILE 277 221 221 ILE ILE R . n 
C 2 278 VAL 278 222 222 VAL VAL R . n 
C 2 279 PRO 279 223 223 PRO PRO R . n 
C 2 280 LEU 280 224 224 LEU LEU R . n 
C 2 281 LEU 281 225 225 LEU LEU R . n 
C 2 282 ILE 282 226 226 ILE ILE R . n 
C 2 283 MET 283 227 227 MET MET R . n 
C 2 284 LEU 284 228 228 LEU LEU R . n 
C 2 285 PHE 285 229 229 PHE PHE R . n 
C 2 286 CYS 286 230 230 CYS CYS R . n 
C 2 287 TYR 287 231 231 TYR TYR R . n 
C 2 288 GLY 288 232 232 GLY GLY R . n 
C 2 289 PHE 289 233 233 PHE PHE R . n 
C 2 290 THR 290 234 234 THR THR R . n 
C 2 291 LEU 291 235 235 LEU LEU R . n 
C 2 292 ARG 292 236 236 ARG ARG R . n 
C 2 293 THR 293 237 237 THR THR R . n 
C 2 294 LEU 294 238 238 LEU LEU R . n 
C 2 295 PHE 295 239 239 PHE PHE R . n 
C 2 296 LYS 296 240 240 LYS LYS R . n 
C 2 297 ALA 297 241 241 ALA ALA R . n 
C 2 298 HIS 298 242 242 HIS HIS R . n 
C 2 299 MET 299 243 243 MET MET R . n 
C 2 300 GLY 300 244 244 GLY GLY R . n 
C 2 301 GLN 301 245 245 GLN GLN R . n 
C 2 302 LYS 302 246 246 LYS LYS R . n 
C 2 303 HIS 303 247 247 HIS HIS R . n 
C 2 304 ARG 304 248 248 ARG ARG R . n 
C 2 305 ALA 305 249 249 ALA ALA R . n 
C 2 306 MET 306 250 250 MET MET R . n 
C 2 307 ARG 307 251 251 ARG ARG R . n 
C 2 308 VAL 308 252 252 VAL VAL R . n 
C 2 309 ILE 309 253 253 ILE ILE R . n 
C 2 310 PHE 310 254 254 PHE PHE R . n 
C 2 311 ALA 311 255 255 ALA ALA R . n 
C 2 312 VAL 312 256 256 VAL VAL R . n 
C 2 313 VAL 313 257 257 VAL VAL R . n 
C 2 314 LEU 314 258 258 LEU LEU R . n 
C 2 315 ILE 315 259 259 ILE ILE R . n 
C 2 316 PHE 316 260 260 PHE PHE R . n 
C 2 317 LEU 317 261 261 LEU LEU R . n 
C 2 318 LEU 318 262 262 LEU LEU R . n 
C 2 319 CYS 319 263 263 CYS CYS R . n 
C 2 320 TRP 320 264 264 TRP TRP R . n 
C 2 321 LEU 321 265 265 LEU LEU R . n 
C 2 322 PRO 322 266 266 PRO PRO R . n 
C 2 323 TYR 323 267 267 TYR TYR R . n 
C 2 324 ASN 324 268 268 ASN ASN R . n 
C 2 325 LEU 325 269 269 LEU LEU R . n 
C 2 326 VAL 326 270 270 VAL VAL R . n 
C 2 327 LEU 327 271 271 LEU LEU R . n 
C 2 328 LEU 328 272 272 LEU LEU R . n 
C 2 329 ALA 329 273 273 ALA ALA R . n 
C 2 330 ASP 330 274 274 ASP ASP R . n 
C 2 331 THR 331 275 275 THR THR R . n 
C 2 332 LEU 332 276 276 LEU LEU R . n 
C 2 333 MET 333 277 277 MET MET R . n 
C 2 334 ARG 334 278 278 ARG ARG R . n 
C 2 335 THR 335 279 279 THR THR R . n 
C 2 336 GLN 336 280 280 GLN GLN R . n 
C 2 337 VAL 337 281 281 VAL VAL R . n 
C 2 338 ILE 338 282 282 ILE ILE R . n 
C 2 339 GLN 339 283 283 GLN GLN R . n 
C 2 340 GLU 340 284 284 GLU GLU R . n 
C 2 341 THR 341 285 285 THR THR R . n 
C 2 342 CYS 342 286 286 CYS CYS R . n 
C 2 343 GLU 343 287 287 GLU GLU R . n 
C 2 344 ARG 344 288 288 ARG ARG R . n 
C 2 345 ARG 345 289 289 ARG ARG R . n 
C 2 346 ASN 346 290 290 ASN ASN R . n 
C 2 347 HIS 347 291 291 HIS HIS R . n 
C 2 348 ILE 348 292 292 ILE ILE R . n 
C 2 349 ASP 349 293 293 ASP ASP R . n 
C 2 350 ARG 350 294 294 ARG ARG R . n 
C 2 351 ALA 351 295 295 ALA ALA R . n 
C 2 352 LEU 352 296 296 LEU LEU R . n 
C 2 353 ASP 353 297 297 ASP ASP R . n 
C 2 354 ALA 354 298 298 ALA ALA R . n 
C 2 355 THR 355 299 299 THR THR R . n 
C 2 356 GLU 356 300 300 GLU GLU R . n 
C 2 357 ILE 357 301 301 ILE ILE R . n 
C 2 358 LEU 358 302 302 LEU LEU R . n 
C 2 359 GLY 359 303 303 GLY GLY R . n 
C 2 360 ILE 360 304 304 ILE ILE R . n 
C 2 361 LEU 361 305 305 LEU LEU R . n 
C 2 362 HIS 362 306 306 HIS HIS R . n 
C 2 363 SER 363 307 307 SER SER R . n 
C 2 364 CYS 364 308 308 CYS CYS R . n 
C 2 365 LEU 365 309 309 LEU LEU R . n 
C 2 366 ASN 366 310 310 ASN ASN R . n 
C 2 367 PRO 367 311 311 PRO PRO R . n 
C 2 368 LEU 368 312 312 LEU LEU R . n 
C 2 369 ILE 369 313 313 ILE ILE R . n 
C 2 370 TYR 370 314 314 TYR TYR R . n 
C 2 371 ALA 371 315 315 ALA ALA R . n 
C 2 372 PHE 372 316 316 PHE PHE R . n 
C 2 373 ILE 373 317 317 ILE ILE R . n 
C 2 374 GLY 374 318 318 GLY GLY R . n 
C 2 375 GLN 375 319 319 GLN GLN R . n 
C 2 376 LYS 376 320 320 LYS LYS R . n 
C 2 377 PHE 377 321 321 PHE PHE R . n 
C 2 378 ARG 378 322 322 ARG ARG R . n 
C 2 379 HIS 379 323 323 HIS HIS R . n 
C 2 380 GLY 380 324 324 GLY GLY R . n 
C 2 381 LEU 381 325 325 LEU LEU R . n 
C 2 382 LEU 382 326 326 LEU LEU R . n 
C 2 383 LYS 383 327 327 LYS LYS R . n 
C 2 384 ILE 384 328 328 ILE ILE R . n 
C 2 385 LEU 385 329 329 LEU LEU R . n 
C 2 386 ALA 386 330 330 ALA ALA R . n 
C 2 387 ILE 387 331 ?   ?   ?   R . n 
C 2 388 HIS 388 332 ?   ?   ?   R . n 
C 2 389 GLY 389 333 ?   ?   ?   R . n 
C 2 390 LEU 390 334 ?   ?   ?   R . n 
C 2 391 ILE 391 335 ?   ?   ?   R . n 
C 2 392 SER 392 336 ?   ?   ?   R . n 
C 2 393 LYS 393 337 ?   ?   ?   R . n 
C 2 394 ASP 394 338 ?   ?   ?   R . n 
C 2 395 SER 395 339 ?   ?   ?   R . n 
C 2 396 LEU 396 340 ?   ?   ?   R . n 
C 2 397 PRO 397 341 ?   ?   ?   R . n 
C 2 398 LYS 398 342 ?   ?   ?   R . n 
C 2 399 ASP 399 343 ?   ?   ?   R . n 
C 2 400 SER 400 344 ?   ?   ?   R . n 
C 2 401 ARG 401 345 ?   ?   ?   R . n 
C 2 402 PRO 402 346 ?   ?   ?   R . n 
C 2 403 SER 403 347 ?   ?   ?   R . n 
C 2 404 PHE 404 348 ?   ?   ?   R . n 
C 2 405 VAL 405 349 ?   ?   ?   R . n 
C 2 406 GLY 406 350 ?   ?   ?   R . n 
C 2 407 SER 407 351 ?   ?   ?   R . n 
C 2 408 SER 408 352 ?   ?   ?   R . n 
C 2 409 SER 409 353 ?   ?   ?   R . n 
C 2 410 GLY 410 354 ?   ?   ?   R . n 
C 2 411 HIS 411 355 ?   ?   ?   R . n 
C 2 412 THR 412 356 ?   ?   ?   R . n 
C 2 413 SER 413 357 ?   ?   ?   R . n 
C 2 414 THR 414 358 ?   ?   ?   R . n 
C 2 415 THR 415 359 ?   ?   ?   R . n 
C 2 416 LEU 416 360 ?   ?   ?   R . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 D GLN 13 ? CG  ? A GLN 13  CG  
2  1 Y 1 D GLN 13 ? CD  ? A GLN 13  CD  
3  1 Y 1 D GLN 13 ? OE1 ? A GLN 13  OE1 
4  1 Y 1 D GLN 13 ? NE2 ? A GLN 13  NE2 
5  1 Y 1 D ASN 22 ? CG  ? A ASN 22  CG  
6  1 Y 1 D ASN 22 ? OD1 ? A ASN 22  OD1 
7  1 Y 1 D ASN 22 ? ND2 ? A ASN 22  ND2 
8  1 Y 1 E LYS 21 ? CG  ? B LYS 21  CG  
9  1 Y 1 E LYS 21 ? CD  ? B LYS 21  CD  
10 1 Y 1 E LYS 21 ? CE  ? B LYS 21  CE  
11 1 Y 1 E LYS 21 ? NZ  ? B LYS 21  NZ  
12 1 Y 1 E LYS 29 ? CG  ? B LYS 29  CG  
13 1 Y 1 E LYS 29 ? CD  ? B LYS 29  CD  
14 1 Y 1 E LYS 29 ? CE  ? B LYS 29  CE  
15 1 Y 1 E LYS 29 ? NZ  ? B LYS 29  NZ  
16 1 Y 1 E GLN 37 ? CG  ? B GLN 37  CG  
17 1 Y 1 E GLN 37 ? CD  ? B GLN 37  CD  
18 1 Y 1 E GLN 37 ? OE1 ? B GLN 37  OE1 
19 1 Y 1 E GLN 37 ? NE2 ? B GLN 37  NE2 
20 1 Y 1 E GLU 39 ? CG  ? B GLU 39  CG  
21 1 Y 1 E GLU 39 ? CD  ? B GLU 39  CD  
22 1 Y 1 E GLU 39 ? OE1 ? B GLU 39  OE1 
23 1 Y 1 E GLU 39 ? OE2 ? B GLU 39  OE2 
24 1 Y 1 E LYS 61 ? CG  ? B LYS 61  CG  
25 1 Y 1 E LYS 61 ? CD  ? B LYS 61  CD  
26 1 Y 1 E LYS 61 ? CE  ? B LYS 61  CE  
27 1 Y 1 E LYS 61 ? NZ  ? B LYS 61  NZ  
28 1 Y 1 E GLU 64 ? CG  ? B GLU 64  CG  
29 1 Y 1 E GLU 64 ? CD  ? B GLU 64  CD  
30 1 Y 1 E GLU 64 ? OE1 ? B GLU 64  OE1 
31 1 Y 1 E GLU 64 ? OE2 ? B GLU 64  OE2 
32 1 Y 1 R GLU 42 ? CG  ? C GLU 98  CG  
33 1 Y 1 R GLU 42 ? CD  ? C GLU 98  CD  
34 1 Y 1 R GLU 42 ? OE1 ? C GLU 98  OE1 
35 1 Y 1 R GLU 42 ? OE2 ? C GLU 98  OE2 
36 1 Y 1 R LEU 44 ? CG  ? C LEU 100 CG  
37 1 Y 1 R LEU 44 ? CD1 ? C LEU 100 CD1 
38 1 Y 1 R LEU 44 ? CD2 ? C LEU 100 CD2 
39 1 Y 1 R GLU 45 ? CG  ? C GLU 101 CG  
40 1 Y 1 R GLU 45 ? CD  ? C GLU 101 CD  
41 1 Y 1 R GLU 45 ? OE1 ? C GLU 101 OE1 
42 1 Y 1 R GLU 45 ? OE2 ? C GLU 101 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XWA 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XWA 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XWA 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8XWA 
_struct.title                        'Structure of CXCR2 bound to CXCL1 (Ligand-receptor focused map)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XWA 
_struct_keywords.text            'GPCR, Arrestin, SIGNALING PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GROA_HUMAN  P09341 ? 1 ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN 35 
2 UNP CXCR2_HUMAN P25025 ? 2 
;EDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRS
VTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL
VKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKA
HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKF
RHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
;
2  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XWA D 1  ? 73  ? P09341 35 ? 107 ? 1 73  
2 1 8XWA E 1  ? 73  ? P09341 35 ? 107 ? 1 73  
3 2 8XWA R 58 ? 416 ? P25025 2  ? 360 ? 2 360 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 8XWA MET R 1  ? UNP P25025 ? ? 'initiating methionine' -55 1  
3 8XWA GLY R 2  ? UNP P25025 ? ? 'expression tag'        -54 2  
3 8XWA LYS R 3  ? UNP P25025 ? ? 'expression tag'        -53 3  
3 8XWA THR R 4  ? UNP P25025 ? ? 'expression tag'        -52 4  
3 8XWA ILE R 5  ? UNP P25025 ? ? 'expression tag'        -51 5  
3 8XWA ILE R 6  ? UNP P25025 ? ? 'expression tag'        -50 6  
3 8XWA ALA R 7  ? UNP P25025 ? ? 'expression tag'        -49 7  
3 8XWA LEU R 8  ? UNP P25025 ? ? 'expression tag'        -48 8  
3 8XWA SER R 9  ? UNP P25025 ? ? 'expression tag'        -47 9  
3 8XWA TYR R 10 ? UNP P25025 ? ? 'expression tag'        -46 10 
3 8XWA ILE R 11 ? UNP P25025 ? ? 'expression tag'        -45 11 
3 8XWA PHE R 12 ? UNP P25025 ? ? 'expression tag'        -44 12 
3 8XWA CYS R 13 ? UNP P25025 ? ? 'expression tag'        -43 13 
3 8XWA LEU R 14 ? UNP P25025 ? ? 'expression tag'        -42 14 
3 8XWA VAL R 15 ? UNP P25025 ? ? 'expression tag'        -41 15 
3 8XWA PHE R 16 ? UNP P25025 ? ? 'expression tag'        -40 16 
3 8XWA ALA R 17 ? UNP P25025 ? ? 'expression tag'        -39 17 
3 8XWA ASP R 18 ? UNP P25025 ? ? 'expression tag'        -38 18 
3 8XWA TYR R 19 ? UNP P25025 ? ? 'expression tag'        -37 19 
3 8XWA LYS R 20 ? UNP P25025 ? ? 'expression tag'        -36 20 
3 8XWA ASP R 21 ? UNP P25025 ? ? 'expression tag'        -35 21 
3 8XWA ASP R 22 ? UNP P25025 ? ? 'expression tag'        -34 22 
3 8XWA ASP R 23 ? UNP P25025 ? ? 'expression tag'        -33 23 
3 8XWA ASP R 24 ? UNP P25025 ? ? 'expression tag'        -32 24 
3 8XWA ALA R 25 ? UNP P25025 ? ? 'expression tag'        -31 25 
3 8XWA ALA R 26 ? UNP P25025 ? ? 'expression tag'        -30 26 
3 8XWA ASN R 27 ? UNP P25025 ? ? 'expression tag'        -29 27 
3 8XWA PHE R 28 ? UNP P25025 ? ? 'expression tag'        -28 28 
3 8XWA THR R 29 ? UNP P25025 ? ? 'expression tag'        -27 29 
3 8XWA PRO R 30 ? UNP P25025 ? ? 'expression tag'        -26 30 
3 8XWA VAL R 31 ? UNP P25025 ? ? 'expression tag'        -25 31 
3 8XWA ASN R 32 ? UNP P25025 ? ? 'expression tag'        -24 32 
3 8XWA GLY R 33 ? UNP P25025 ? ? 'expression tag'        -23 33 
3 8XWA SER R 34 ? UNP P25025 ? ? 'expression tag'        -22 34 
3 8XWA SER R 35 ? UNP P25025 ? ? 'expression tag'        -21 35 
3 8XWA GLY R 36 ? UNP P25025 ? ? 'expression tag'        -20 36 
3 8XWA ASN R 37 ? UNP P25025 ? ? 'expression tag'        -19 37 
3 8XWA GLN R 38 ? UNP P25025 ? ? 'expression tag'        -18 38 
3 8XWA SER R 39 ? UNP P25025 ? ? 'expression tag'        -17 39 
3 8XWA VAL R 40 ? UNP P25025 ? ? 'expression tag'        -16 40 
3 8XWA ARG R 41 ? UNP P25025 ? ? 'expression tag'        -15 41 
3 8XWA LEU R 42 ? UNP P25025 ? ? 'expression tag'        -14 42 
3 8XWA VAL R 43 ? UNP P25025 ? ? 'expression tag'        -13 43 
3 8XWA THR R 44 ? UNP P25025 ? ? 'expression tag'        -12 44 
3 8XWA SER R 45 ? UNP P25025 ? ? 'expression tag'        -11 45 
3 8XWA SER R 46 ? UNP P25025 ? ? 'expression tag'        -10 46 
3 8XWA SER R 47 ? UNP P25025 ? ? 'expression tag'        -9  47 
3 8XWA LEU R 48 ? UNP P25025 ? ? 'expression tag'        -8  48 
3 8XWA GLU R 49 ? UNP P25025 ? ? 'expression tag'        -7  49 
3 8XWA VAL R 50 ? UNP P25025 ? ? 'expression tag'        -6  50 
3 8XWA LEU R 51 ? UNP P25025 ? ? 'expression tag'        -5  51 
3 8XWA PHE R 52 ? UNP P25025 ? ? 'expression tag'        -4  52 
3 8XWA GLN R 53 ? UNP P25025 ? ? 'expression tag'        -3  53 
3 8XWA GLY R 54 ? UNP P25025 ? ? 'expression tag'        -2  54 
3 8XWA PRO R 55 ? UNP P25025 ? ? 'expression tag'        -1  55 
3 8XWA GLY R 56 ? UNP P25025 ? ? 'expression tag'        0   56 
3 8XWA SER R 57 ? UNP P25025 ? ? 'expression tag'        1   57 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 HIS A 19  ? LYS A 21  ? HIS D 19  LYS D 21  5 ? 3  
HELX_P HELX_P2  AA2 SER A 56  ? ASN A 68  ? SER D 56  ASN D 68  1 ? 13 
HELX_P HELX_P3  AA3 HIS B 19  ? LYS B 21  ? HIS E 19  LYS E 21  5 ? 3  
HELX_P HELX_P4  AA4 SER B 56  ? ASN B 68  ? SER E 56  ASN E 68  1 ? 13 
HELX_P HELX_P5  AA5 LEU C 100 ? SER C 132 ? LEU R 44  SER R 76  1 ? 33 
HELX_P HELX_P6  AA6 SER C 137 ? THR C 156 ? SER R 81  THR R 100 1 ? 20 
HELX_P HELX_P7  AA7 THR C 156 ? GLY C 167 ? THR R 100 GLY R 111 1 ? 12 
HELX_P HELX_P8  AA8 GLY C 171 ? VAL C 205 ? GLY R 115 VAL R 149 1 ? 35 
HELX_P HELX_P9  AA9 ARG C 209 ? TYR C 216 ? ARG R 153 TYR R 160 5 ? 8  
HELX_P HELX_P10 AB1 LEU C 217 ? ALA C 233 ? LEU R 161 ALA R 177 1 ? 17 
HELX_P HELX_P11 AB2 ALA C 233 ? PHE C 239 ? ALA R 177 PHE R 183 1 ? 7  
HELX_P HELX_P12 AB3 ASN C 259 ? ARG C 268 ? ASN R 203 ARG R 212 1 ? 10 
HELX_P HELX_P13 AB4 ARG C 268 ? PHE C 274 ? ARG R 212 PHE R 218 1 ? 7  
HELX_P HELX_P14 AB5 PHE C 276 ? PHE C 295 ? PHE R 220 PHE R 239 1 ? 20 
HELX_P HELX_P15 AB6 GLN C 301 ? THR C 335 ? GLN R 245 THR R 279 1 ? 35 
HELX_P HELX_P16 AB7 THR C 341 ? LEU C 361 ? THR R 285 LEU R 305 1 ? 21 
HELX_P HELX_P17 AB8 LEU C 361 ? ALA C 371 ? LEU R 305 ALA R 315 1 ? 11 
HELX_P HELX_P18 AB9 GLY C 374 ? ALA C 386 ? GLY R 318 ALA R 330 1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 9   SG ? ? ? 1_555 A CYS 35  SG ? ? D CYS 9   D CYS 35  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ? ? A CYS 11  SG ? ? ? 1_555 A CYS 51  SG ? ? D CYS 11  D CYS 51  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3 disulf ? ? B CYS 9   SG ? ? ? 1_555 B CYS 35  SG ? ? E CYS 9   E CYS 35  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf4 disulf ? ? B CYS 11  SG ? ? ? 1_555 B CYS 51  SG ? ? E CYS 11  E CYS 51  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf5 disulf ? ? C CYS 95  SG ? ? ? 1_555 C CYS 342 SG ? ? R CYS 39  R CYS 286 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf6 disulf ? ? C CYS 175 SG ? ? ? 1_555 C CYS 252 SG ? ? R CYS 119 R CYS 196 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 9   ? CYS A 35  ? CYS D 9   ? 1_555 CYS D 35  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 11  ? CYS A 51  ? CYS D 11  ? 1_555 CYS D 51  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 9   ? CYS B 35  ? CYS E 9   ? 1_555 CYS E 35  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 11  ? CYS B 51  ? CYS E 11  ? 1_555 CYS E 51  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS C 95  ? CYS C 342 ? CYS R 39  ? 1_555 CYS R 286 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS C 175 ? CYS C 252 ? CYS R 119 ? 1_555 CYS R 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 49  ? LEU A 52  ? LYS D 49  LEU D 52  
AA1 2 GLU A 39  ? LEU A 44  ? GLU D 39  LEU D 44  
AA1 3 ILE A 23  ? LYS A 29  ? ILE D 23  LYS D 29  
AA1 4 ILE B 23  ? LYS B 29  ? ILE E 23  LYS E 29  
AA1 5 GLU B 39  ? LEU B 44  ? GLU E 39  LEU E 44  
AA1 6 LYS B 49  ? LEU B 52  ? LYS E 49  LEU E 52  
AA2 1 ARG C 240 ? VAL C 243 ? ARG R 184 VAL R 187 
AA2 2 ALA C 251 ? GLU C 254 ? ALA R 195 GLU R 198 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ALA A 50  ? O ALA D 50  N ALA A 42  ? N ALA D 42  
AA1 2 3 O ILE A 41  ? O ILE D 41  N ASN A 27  ? N ASN D 27  
AA1 3 4 N VAL A 26  ? N VAL D 26  O VAL B 28  ? O VAL E 28  
AA1 4 5 N ASN B 27  ? N ASN E 27  O ILE B 41  ? O ILE E 41  
AA1 5 6 N ALA B 42  ? N ALA E 42  O ALA B 50  ? O ALA E 50  
AA2 1 2 N VAL C 243 ? N VAL R 187 O ALA C 251 ? O ALA R 195 
# 
_pdbx_entry_details.entry_id                   8XWA 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    ASN 
_pdbx_validate_torsion.auth_asym_id    R 
_pdbx_validate_torsion.auth_seq_id     203 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -98.37 
_pdbx_validate_torsion.psi             34.37 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8XWA 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   SwissModel 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    8XWA 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.48 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               115169 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 RECOMBINANT COMPLEX 'C-X-C chemokine receptor type 2 in complex with C-X-C motif chemokine 1' ? ? ? 1,2 
2 1 RECOMBINANT COMPLEX 'C-X-C chemokine receptor type 2'                                         ? ? ? 2   
3 1 RECOMBINANT COMPLEX 'C-X-C motif chemokine 1'                                                 ? ? ? 1   
# 
_em_image_scans.entry_id                8XWA 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        40 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8XWA 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              8XWA 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8XWA 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 D SER 69  ? A SER 69  
2   1 Y 1 D ASP 70  ? A ASP 70  
3   1 Y 1 D LYS 71  ? A LYS 71  
4   1 Y 1 D SER 72  ? A SER 72  
5   1 Y 1 D ASN 73  ? A ASN 73  
6   1 Y 1 E ALA 1   ? B ALA 1   
7   1 Y 1 E SER 2   ? B SER 2   
8   1 Y 1 E VAL 3   ? B VAL 3   
9   1 Y 1 E ALA 4   ? B ALA 4   
10  1 Y 1 E THR 5   ? B THR 5   
11  1 Y 1 E GLU 6   ? B GLU 6   
12  1 Y 1 E LEU 7   ? B LEU 7   
13  1 Y 1 E ARG 8   ? B ARG 8   
14  1 Y 1 E ASP 70  ? B ASP 70  
15  1 Y 1 E LYS 71  ? B LYS 71  
16  1 Y 1 E SER 72  ? B SER 72  
17  1 Y 1 E ASN 73  ? B ASN 73  
18  1 Y 1 R MET -55 ? C MET 1   
19  1 Y 1 R GLY -54 ? C GLY 2   
20  1 Y 1 R LYS -53 ? C LYS 3   
21  1 Y 1 R THR -52 ? C THR 4   
22  1 Y 1 R ILE -51 ? C ILE 5   
23  1 Y 1 R ILE -50 ? C ILE 6   
24  1 Y 1 R ALA -49 ? C ALA 7   
25  1 Y 1 R LEU -48 ? C LEU 8   
26  1 Y 1 R SER -47 ? C SER 9   
27  1 Y 1 R TYR -46 ? C TYR 10  
28  1 Y 1 R ILE -45 ? C ILE 11  
29  1 Y 1 R PHE -44 ? C PHE 12  
30  1 Y 1 R CYS -43 ? C CYS 13  
31  1 Y 1 R LEU -42 ? C LEU 14  
32  1 Y 1 R VAL -41 ? C VAL 15  
33  1 Y 1 R PHE -40 ? C PHE 16  
34  1 Y 1 R ALA -39 ? C ALA 17  
35  1 Y 1 R ASP -38 ? C ASP 18  
36  1 Y 1 R TYR -37 ? C TYR 19  
37  1 Y 1 R LYS -36 ? C LYS 20  
38  1 Y 1 R ASP -35 ? C ASP 21  
39  1 Y 1 R ASP -34 ? C ASP 22  
40  1 Y 1 R ASP -33 ? C ASP 23  
41  1 Y 1 R ASP -32 ? C ASP 24  
42  1 Y 1 R ALA -31 ? C ALA 25  
43  1 Y 1 R ALA -30 ? C ALA 26  
44  1 Y 1 R ASN -29 ? C ASN 27  
45  1 Y 1 R PHE -28 ? C PHE 28  
46  1 Y 1 R THR -27 ? C THR 29  
47  1 Y 1 R PRO -26 ? C PRO 30  
48  1 Y 1 R VAL -25 ? C VAL 31  
49  1 Y 1 R ASN -24 ? C ASN 32  
50  1 Y 1 R GLY -23 ? C GLY 33  
51  1 Y 1 R SER -22 ? C SER 34  
52  1 Y 1 R SER -21 ? C SER 35  
53  1 Y 1 R GLY -20 ? C GLY 36  
54  1 Y 1 R ASN -19 ? C ASN 37  
55  1 Y 1 R GLN -18 ? C GLN 38  
56  1 Y 1 R SER -17 ? C SER 39  
57  1 Y 1 R VAL -16 ? C VAL 40  
58  1 Y 1 R ARG -15 ? C ARG 41  
59  1 Y 1 R LEU -14 ? C LEU 42  
60  1 Y 1 R VAL -13 ? C VAL 43  
61  1 Y 1 R THR -12 ? C THR 44  
62  1 Y 1 R SER -11 ? C SER 45  
63  1 Y 1 R SER -10 ? C SER 46  
64  1 Y 1 R SER -9  ? C SER 47  
65  1 Y 1 R LEU -8  ? C LEU 48  
66  1 Y 1 R GLU -7  ? C GLU 49  
67  1 Y 1 R VAL -6  ? C VAL 50  
68  1 Y 1 R LEU -5  ? C LEU 51  
69  1 Y 1 R PHE -4  ? C PHE 52  
70  1 Y 1 R GLN -3  ? C GLN 53  
71  1 Y 1 R GLY -2  ? C GLY 54  
72  1 Y 1 R PRO -1  ? C PRO 55  
73  1 Y 1 R GLY 0   ? C GLY 56  
74  1 Y 1 R SER 1   ? C SER 57  
75  1 Y 1 R GLU 2   ? C GLU 58  
76  1 Y 1 R ASP 3   ? C ASP 59  
77  1 Y 1 R PHE 4   ? C PHE 60  
78  1 Y 1 R ASN 5   ? C ASN 61  
79  1 Y 1 R MET 6   ? C MET 62  
80  1 Y 1 R GLU 7   ? C GLU 63  
81  1 Y 1 R SER 8   ? C SER 64  
82  1 Y 1 R ASP 9   ? C ASP 65  
83  1 Y 1 R SER 10  ? C SER 66  
84  1 Y 1 R PHE 11  ? C PHE 67  
85  1 Y 1 R GLU 12  ? C GLU 68  
86  1 Y 1 R ASP 13  ? C ASP 69  
87  1 Y 1 R PHE 14  ? C PHE 70  
88  1 Y 1 R TRP 15  ? C TRP 71  
89  1 Y 1 R LYS 16  ? C LYS 72  
90  1 Y 1 R GLY 17  ? C GLY 73  
91  1 Y 1 R GLU 18  ? C GLU 74  
92  1 Y 1 R ASP 19  ? C ASP 75  
93  1 Y 1 R LEU 20  ? C LEU 76  
94  1 Y 1 R SER 21  ? C SER 77  
95  1 Y 1 R ASN 22  ? C ASN 78  
96  1 Y 1 R TYR 23  ? C TYR 79  
97  1 Y 1 R SER 24  ? C SER 80  
98  1 Y 1 R TYR 25  ? C TYR 81  
99  1 Y 1 R SER 26  ? C SER 82  
100 1 Y 1 R SER 27  ? C SER 83  
101 1 Y 1 R THR 28  ? C THR 84  
102 1 Y 1 R LEU 29  ? C LEU 85  
103 1 Y 1 R PRO 30  ? C PRO 86  
104 1 Y 1 R PRO 31  ? C PRO 87  
105 1 Y 1 R PHE 32  ? C PHE 88  
106 1 Y 1 R LEU 33  ? C LEU 89  
107 1 Y 1 R ILE 331 ? C ILE 387 
108 1 Y 1 R HIS 332 ? C HIS 388 
109 1 Y 1 R GLY 333 ? C GLY 389 
110 1 Y 1 R LEU 334 ? C LEU 390 
111 1 Y 1 R ILE 335 ? C ILE 391 
112 1 Y 1 R SER 336 ? C SER 392 
113 1 Y 1 R LYS 337 ? C LYS 393 
114 1 Y 1 R ASP 338 ? C ASP 394 
115 1 Y 1 R SER 339 ? C SER 395 
116 1 Y 1 R LEU 340 ? C LEU 396 
117 1 Y 1 R PRO 341 ? C PRO 397 
118 1 Y 1 R LYS 342 ? C LYS 398 
119 1 Y 1 R ASP 343 ? C ASP 399 
120 1 Y 1 R SER 344 ? C SER 400 
121 1 Y 1 R ARG 345 ? C ARG 401 
122 1 Y 1 R PRO 346 ? C PRO 402 
123 1 Y 1 R SER 347 ? C SER 403 
124 1 Y 1 R PHE 348 ? C PHE 404 
125 1 Y 1 R VAL 349 ? C VAL 405 
126 1 Y 1 R GLY 350 ? C GLY 406 
127 1 Y 1 R SER 351 ? C SER 407 
128 1 Y 1 R SER 352 ? C SER 408 
129 1 Y 1 R SER 353 ? C SER 409 
130 1 Y 1 R GLY 354 ? C GLY 410 
131 1 Y 1 R HIS 355 ? C HIS 411 
132 1 Y 1 R THR 356 ? C THR 412 
133 1 Y 1 R SER 357 ? C SER 413 
134 1 Y 1 R THR 358 ? C THR 414 
135 1 Y 1 R THR 359 ? C THR 415 
136 1 Y 1 R LEU 360 ? C LEU 416 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-16 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8XWA 
_em_admin.last_update        2025-04-09 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'Structure of CXCR2 bound to CXCL1 (Ligand-receptor focused map)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
loop_
_em_entity_assembly_molwt.entity_assembly_id 
_em_entity_assembly_molwt.experimental_flag 
_em_entity_assembly_molwt.id 
_em_entity_assembly_molwt.units 
_em_entity_assembly_molwt.value 
1 NO 1 ? ? 
1 NO 2 ? ? 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 9606 'Homo sapiens' ? ? ? ? ? 
? ? 2 3 9606 'Homo sapiens' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 1 2 7108 'Spodoptera frugiperda' ? ? 
? 2 3 562  'Escherichia coli'      ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.4 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   4437786 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ?   
MASKING                    ? 3  ? ? ? ?         ?   
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC 4.4 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?   
'MODEL FITTING'            ? 7  ? 1 ? Coot      ?   
OTHER                      ? 8  ? ? ? ?         ?   
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    ?   
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?         ?   
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?         ?   
CLASSIFICATION             ? 12 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION             ? 14 1 ? ? RELION    4   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Science and Engineering Research Board (SERB)' 
_pdbx_audit_support.country                India 
_pdbx_audit_support.grant_number           IPA/2020/000405 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      SwissModel 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    8XWA 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 1   ? 146.667 122.332 80.313  1.00 115.62 ? 1   ALA D N   1 
ATOM 2    C CA  . ALA A 1 1   ? 145.393 122.132 79.567  1.00 115.62 ? 1   ALA D CA  1 
ATOM 3    C C   . ALA A 1 1   ? 144.217 122.686 80.363  1.00 115.62 ? 1   ALA D C   1 
ATOM 4    O O   . ALA A 1 1   ? 144.403 123.331 81.394  1.00 115.62 ? 1   ALA D O   1 
ATOM 5    C CB  . ALA A 1 1   ? 145.183 120.657 79.262  1.00 115.62 ? 1   ALA D CB  1 
ATOM 6    N N   . SER A 1 2   ? 143.006 122.431 79.878  1.00 109.43 ? 2   SER D N   1 
ATOM 7    C CA  . SER A 1 2   ? 141.814 122.934 80.538  1.00 109.43 ? 2   SER D CA  1 
ATOM 8    C C   . SER A 1 2   ? 141.570 122.195 81.850  1.00 109.43 ? 2   SER D C   1 
ATOM 9    O O   . SER A 1 2   ? 142.067 121.089 82.079  1.00 109.43 ? 2   SER D O   1 
ATOM 10   C CB  . SER A 1 2   ? 140.597 122.789 79.625  1.00 109.43 ? 2   SER D CB  1 
ATOM 11   O OG  . SER A 1 2   ? 140.915 123.147 78.292  1.00 109.43 ? 2   SER D OG  1 
ATOM 12   N N   . VAL A 1 3   ? 140.793 122.832 82.722  1.00 98.74  ? 3   VAL D N   1 
ATOM 13   C CA  . VAL A 1 3   ? 140.372 122.250 83.991  1.00 98.74  ? 3   VAL D CA  1 
ATOM 14   C C   . VAL A 1 3   ? 138.856 122.345 84.052  1.00 98.74  ? 3   VAL D C   1 
ATOM 15   O O   . VAL A 1 3   ? 138.300 123.451 84.045  1.00 98.74  ? 3   VAL D O   1 
ATOM 16   C CB  . VAL A 1 3   ? 141.009 122.962 85.195  1.00 98.74  ? 3   VAL D CB  1 
ATOM 17   C CG1 . VAL A 1 3   ? 140.375 122.484 86.493  1.00 98.74  ? 3   VAL D CG1 1 
ATOM 18   C CG2 . VAL A 1 3   ? 142.511 122.733 85.212  1.00 98.74  ? 3   VAL D CG2 1 
ATOM 19   N N   . ALA A 1 4   ? 138.189 121.196 84.112  1.00 96.00  ? 4   ALA D N   1 
ATOM 20   C CA  . ALA A 1 4   ? 136.735 121.126 84.073  1.00 96.00  ? 4   ALA D CA  1 
ATOM 21   C C   . ALA A 1 4   ? 136.220 120.437 85.326  1.00 96.00  ? 4   ALA D C   1 
ATOM 22   O O   . ALA A 1 4   ? 136.696 119.354 85.684  1.00 96.00  ? 4   ALA D O   1 
ATOM 23   C CB  . ALA A 1 4   ? 136.257 120.377 82.827  1.00 96.00  ? 4   ALA D CB  1 
ATOM 24   N N   . THR A 1 5   ? 135.251 121.067 85.988  1.00 104.08 ? 5   THR D N   1 
ATOM 25   C CA  . THR A 1 5   ? 134.563 120.445 87.109  1.00 104.08 ? 5   THR D CA  1 
ATOM 26   C C   . THR A 1 5   ? 133.427 119.537 86.663  1.00 104.08 ? 5   THR D C   1 
ATOM 27   O O   . THR A 1 5   ? 132.883 118.794 87.487  1.00 104.08 ? 5   THR D O   1 
ATOM 28   C CB  . THR A 1 5   ? 134.015 121.520 88.056  1.00 104.08 ? 5   THR D CB  1 
ATOM 29   O OG1 . THR A 1 5   ? 133.743 120.941 89.338  1.00 104.08 ? 5   THR D OG1 1 
ATOM 30   C CG2 . THR A 1 5   ? 132.741 122.136 87.496  1.00 104.08 ? 5   THR D CG2 1 
ATOM 31   N N   . GLU A 1 6   ? 133.059 119.583 85.384  1.00 93.93  ? 6   GLU D N   1 
ATOM 32   C CA  . GLU A 1 6   ? 132.059 118.700 84.805  1.00 93.93  ? 6   GLU D CA  1 
ATOM 33   C C   . GLU A 1 6   ? 132.628 118.071 83.544  1.00 93.93  ? 6   GLU D C   1 
ATOM 34   O O   . GLU A 1 6   ? 133.315 118.737 82.765  1.00 93.93  ? 6   GLU D O   1 
ATOM 35   C CB  . GLU A 1 6   ? 130.767 119.454 84.468  1.00 93.93  ? 6   GLU D CB  1 
ATOM 36   C CG  . GLU A 1 6   ? 130.106 120.125 85.658  1.00 93.93  ? 6   GLU D CG  1 
ATOM 37   C CD  . GLU A 1 6   ? 129.402 119.139 86.566  1.00 93.93  ? 6   GLU D CD  1 
ATOM 38   O OE1 . GLU A 1 6   ? 128.532 118.391 86.071  1.00 93.93  ? 6   GLU D OE1 1 
ATOM 39   O OE2 . GLU A 1 6   ? 129.718 119.109 87.773  1.00 93.93  ? 6   GLU D OE2 1 
ATOM 40   N N   . LEU A 1 7   ? 132.340 116.788 83.348  1.00 82.63  ? 7   LEU D N   1 
ATOM 41   C CA  . LEU A 1 7   ? 132.746 116.062 82.153  1.00 82.63  ? 7   LEU D CA  1 
ATOM 42   C C   . LEU A 1 7   ? 131.518 115.798 81.296  1.00 82.63  ? 7   LEU D C   1 
ATOM 43   O O   . LEU A 1 7   ? 130.498 115.314 81.798  1.00 82.63  ? 7   LEU D O   1 
ATOM 44   C CB  . LEU A 1 7   ? 133.440 114.747 82.513  1.00 82.63  ? 7   LEU D CB  1 
ATOM 45   C CG  . LEU A 1 7   ? 134.634 114.868 83.461  1.00 82.63  ? 7   LEU D CG  1 
ATOM 46   C CD1 . LEU A 1 7   ? 135.052 113.501 83.973  1.00 82.63  ? 7   LEU D CD1 1 
ATOM 47   C CD2 . LEU A 1 7   ? 135.797 115.559 82.769  1.00 82.63  ? 7   LEU D CD2 1 
ATOM 48   N N   . ARG A 1 8   ? 131.618 116.118 80.009  1.00 87.47  ? 8   ARG D N   1 
ATOM 49   C CA  . ARG A 1 8   ? 130.505 116.002 79.081  1.00 87.47  ? 8   ARG D CA  1 
ATOM 50   C C   . ARG A 1 8   ? 130.959 115.262 77.832  1.00 87.47  ? 8   ARG D C   1 
ATOM 51   O O   . ARG A 1 8   ? 132.150 115.202 77.518  1.00 87.47  ? 8   ARG D O   1 
ATOM 52   C CB  . ARG A 1 8   ? 129.951 117.379 78.693  1.00 87.47  ? 8   ARG D CB  1 
ATOM 53   C CG  . ARG A 1 8   ? 129.507 118.230 79.870  1.00 87.47  ? 8   ARG D CG  1 
ATOM 54   C CD  . ARG A 1 8   ? 129.347 119.685 79.460  1.00 87.47  ? 8   ARG D CD  1 
ATOM 55   N NE  . ARG A 1 8   ? 129.016 120.544 80.591  1.00 87.47  ? 8   ARG D NE  1 
ATOM 56   C CZ  . ARG A 1 8   ? 127.860 120.520 81.241  1.00 87.47  ? 8   ARG D CZ  1 
ATOM 57   N NH1 . ARG A 1 8   ? 126.883 119.702 80.887  1.00 87.47  ? 8   ARG D NH1 1 
ATOM 58   N NH2 . ARG A 1 8   ? 127.680 121.341 82.271  1.00 87.47  ? 8   ARG D NH2 1 
ATOM 59   N N   . CYS A 1 9   ? 129.989 114.694 77.120  1.00 97.62  ? 9   CYS D N   1 
ATOM 60   C CA  . CYS A 1 9   ? 130.290 114.023 75.864  1.00 97.62  ? 9   CYS D CA  1 
ATOM 61   C C   . CYS A 1 9   ? 130.855 115.020 74.860  1.00 97.62  ? 9   CYS D C   1 
ATOM 62   O O   . CYS A 1 9   ? 130.432 116.176 74.790  1.00 97.62  ? 9   CYS D O   1 
ATOM 63   C CB  . CYS A 1 9   ? 129.034 113.360 75.297  1.00 97.62  ? 9   CYS D CB  1 
ATOM 64   S SG  . CYS A 1 9   ? 128.310 112.092 76.365  1.00 97.62  ? 9   CYS D SG  1 
ATOM 65   N N   . GLN A 1 10  ? 131.823 114.558 74.074  1.00 91.64  ? 10  GLN D N   1 
ATOM 66   C CA  . GLN A 1 10  ? 132.512 115.397 73.103  1.00 91.64  ? 10  GLN D CA  1 
ATOM 67   C C   . GLN A 1 10  ? 131.770 115.497 71.779  1.00 91.64  ? 10  GLN D C   1 
ATOM 68   O O   . GLN A 1 10  ? 132.247 116.179 70.867  1.00 91.64  ? 10  GLN D O   1 
ATOM 69   C CB  . GLN A 1 10  ? 133.923 114.860 72.854  1.00 91.64  ? 10  GLN D CB  1 
ATOM 70   C CG  . GLN A 1 10  ? 134.774 114.738 74.107  1.00 91.64  ? 10  GLN D CG  1 
ATOM 71   C CD  . GLN A 1 10  ? 136.206 114.301 73.826  1.00 91.64  ? 10  GLN D CD  1 
ATOM 72   O OE1 . GLN A 1 10  ? 137.015 114.193 74.747  1.00 91.64  ? 10  GLN D OE1 1 
ATOM 73   N NE2 . GLN A 1 10  ? 136.527 114.045 72.559  1.00 91.64  ? 10  GLN D NE2 1 
ATOM 74   N N   . CYS A 1 11  ? 130.622 114.836 71.650  1.00 93.46  ? 11  CYS D N   1 
ATOM 75   C CA  . CYS A 1 11  ? 129.894 114.780 70.393  1.00 93.46  ? 11  CYS D CA  1 
ATOM 76   C C   . CYS A 1 11  ? 128.442 115.172 70.624  1.00 93.46  ? 11  CYS D C   1 
ATOM 77   O O   . CYS A 1 11  ? 127.819 114.756 71.604  1.00 93.46  ? 11  CYS D O   1 
ATOM 78   C CB  . CYS A 1 11  ? 129.972 113.379 69.778  1.00 93.46  ? 11  CYS D CB  1 
ATOM 79   S SG  . CYS A 1 11  ? 129.447 113.291 68.064  1.00 93.46  ? 11  CYS D SG  1 
ATOM 80   N N   . LEU A 1 12  ? 127.910 115.980 69.705  1.00 100.10 ? 12  LEU D N   1 
ATOM 81   C CA  . LEU A 1 12  ? 126.518 116.409 69.772  1.00 100.10 ? 12  LEU D CA  1 
ATOM 82   C C   . LEU A 1 12  ? 125.721 115.828 68.610  1.00 100.10 ? 12  LEU D C   1 
ATOM 83   O O   . LEU A 1 12  ? 124.706 115.157 68.820  1.00 100.10 ? 12  LEU D O   1 
ATOM 84   C CB  . LEU A 1 12  ? 126.427 117.936 69.763  1.00 100.10 ? 12  LEU D CB  1 
ATOM 85   C CG  . LEU A 1 12  ? 126.953 118.646 71.011  1.00 100.10 ? 12  LEU D CG  1 
ATOM 86   C CD1 . LEU A 1 12  ? 127.082 120.139 70.757  1.00 100.10 ? 12  LEU D CD1 1 
ATOM 87   C CD2 . LEU A 1 12  ? 126.047 118.383 72.203  1.00 100.10 ? 12  LEU D CD2 1 
ATOM 88   N N   . GLN A 1 13  ? 126.172 116.081 67.385  1.00 110.31 ? 13  GLN D N   1 
ATOM 89   C CA  . GLN A 1 13  ? 125.541 115.532 66.196  1.00 110.31 ? 13  GLN D CA  1 
ATOM 90   C C   . GLN A 1 13  ? 126.398 114.382 65.666  1.00 110.31 ? 13  GLN D C   1 
ATOM 91   O O   . GLN A 1 13  ? 127.526 114.166 66.112  1.00 110.31 ? 13  GLN D O   1 
ATOM 92   C CB  . GLN A 1 13  ? 125.349 116.605 65.135  1.00 30.00  ? 13  GLN D CB  1 
ATOM 93   N N   . THR A 1 14  ? 125.875 113.632 64.696  1.00 103.38 ? 14  THR D N   1 
ATOM 94   C CA  . THR A 1 14  ? 126.585 112.469 64.178  1.00 103.38 ? 14  THR D CA  1 
ATOM 95   C C   . THR A 1 14  ? 126.306 112.262 62.695  1.00 103.38 ? 14  THR D C   1 
ATOM 96   O O   . THR A 1 14  ? 125.159 112.366 62.250  1.00 103.38 ? 14  THR D O   1 
ATOM 97   C CB  . THR A 1 14  ? 126.193 111.212 64.959  1.00 103.38 ? 14  THR D CB  1 
ATOM 98   O OG1 . THR A 1 14  ? 124.787 111.233 65.231  1.00 103.38 ? 14  THR D OG1 1 
ATOM 99   C CG2 . THR A 1 14  ? 126.963 111.129 66.268  1.00 103.38 ? 14  THR D CG2 1 
ATOM 100  N N   . LEU A 1 15  ? 127.350 111.968 61.927  1.00 109.55 ? 15  LEU D N   1 
ATOM 101  C CA  . LEU A 1 15  ? 127.221 111.711 60.502  1.00 109.55 ? 15  LEU D CA  1 
ATOM 102  C C   . LEU A 1 15  ? 127.094 110.216 60.240  1.00 109.55 ? 15  LEU D C   1 
ATOM 103  O O   . LEU A 1 15  ? 127.506 109.385 61.054  1.00 109.55 ? 15  LEU D O   1 
ATOM 104  C CB  . LEU A 1 15  ? 128.424 112.268 59.742  1.00 109.55 ? 15  LEU D CB  1 
ATOM 105  C CG  . LEU A 1 15  ? 128.754 113.735 60.011  1.00 109.55 ? 15  LEU D CG  1 
ATOM 106  C CD1 . LEU A 1 15  ? 130.066 114.107 59.343  1.00 109.55 ? 15  LEU D CD1 1 
ATOM 107  C CD2 . LEU A 1 15  ? 127.628 114.635 59.530  1.00 109.55 ? 15  LEU D CD2 1 
ATOM 108  N N   . GLN A 1 16  ? 126.516 109.880 59.086  1.00 111.44 ? 16  GLN D N   1 
ATOM 109  C CA  . GLN A 1 16  ? 126.327 108.482 58.720  1.00 111.44 ? 16  GLN D CA  1 
ATOM 110  C C   . GLN A 1 16  ? 127.548 107.877 58.039  1.00 111.44 ? 16  GLN D C   1 
ATOM 111  O O   . GLN A 1 16  ? 127.599 106.654 57.871  1.00 111.44 ? 16  GLN D O   1 
ATOM 112  C CB  . GLN A 1 16  ? 125.109 108.339 57.806  1.00 111.44 ? 16  GLN D CB  1 
ATOM 113  C CG  . GLN A 1 16  ? 123.784 108.643 58.489  1.00 111.44 ? 16  GLN D CG  1 
ATOM 114  C CD  . GLN A 1 16  ? 123.441 107.636 59.570  1.00 111.44 ? 16  GLN D CD  1 
ATOM 115  O OE1 . GLN A 1 16  ? 124.017 106.550 59.627  1.00 111.44 ? 16  GLN D OE1 1 
ATOM 116  N NE2 . GLN A 1 16  ? 122.499 107.993 60.435  1.00 111.44 ? 16  GLN D NE2 1 
ATOM 117  N N   . GLY A 1 17  ? 128.521 108.689 57.644  1.00 113.63 ? 17  GLY D N   1 
ATOM 118  C CA  . GLY A 1 17  ? 129.723 108.160 57.023  1.00 113.63 ? 17  GLY D CA  1 
ATOM 119  C C   . GLY A 1 17  ? 130.569 109.280 56.461  1.00 113.63 ? 17  GLY D C   1 
ATOM 120  O O   . GLY A 1 17  ? 130.144 110.437 56.381  1.00 113.63 ? 17  GLY D O   1 
ATOM 121  N N   . ILE A 1 18  ? 131.788 108.911 56.069  1.00 106.11 ? 18  ILE D N   1 
ATOM 122  C CA  . ILE A 1 18  ? 132.747 109.841 55.484  1.00 106.11 ? 18  ILE D CA  1 
ATOM 123  C C   . ILE A 1 18  ? 133.613 109.071 54.497  1.00 106.11 ? 18  ILE D C   1 
ATOM 124  O O   . ILE A 1 18  ? 133.796 107.857 54.618  1.00 106.11 ? 18  ILE D O   1 
ATOM 125  C CB  . ILE A 1 18  ? 133.617 110.527 56.565  1.00 106.11 ? 18  ILE D CB  1 
ATOM 126  C CG1 . ILE A 1 18  ? 132.752 111.448 57.432  1.00 106.11 ? 18  ILE D CG1 1 
ATOM 127  C CG2 . ILE A 1 18  ? 134.763 111.309 55.920  1.00 106.11 ? 18  ILE D CG2 1 
ATOM 128  C CD1 . ILE A 1 18  ? 133.516 112.214 58.494  1.00 106.11 ? 18  ILE D CD1 1 
ATOM 129  N N   . HIS A 1 19  ? 134.143 109.785 53.511  1.00 122.74 ? 19  HIS D N   1 
ATOM 130  C CA  . HIS A 1 19  ? 135.019 109.169 52.526  1.00 122.74 ? 19  HIS D CA  1 
ATOM 131  C C   . HIS A 1 19  ? 136.290 108.675 53.213  1.00 122.74 ? 19  HIS D C   1 
ATOM 132  O O   . HIS A 1 19  ? 136.982 109.475 53.861  1.00 122.74 ? 19  HIS D O   1 
ATOM 133  C CB  . HIS A 1 19  ? 135.365 110.168 51.425  1.00 122.74 ? 19  HIS D CB  1 
ATOM 134  C CG  . HIS A 1 19  ? 135.968 109.540 50.207  1.00 122.74 ? 19  HIS D CG  1 
ATOM 135  N ND1 . HIS A 1 19  ? 137.308 109.236 50.111  1.00 122.74 ? 19  HIS D ND1 1 
ATOM 136  C CD2 . HIS A 1 19  ? 135.411 109.159 49.034  1.00 122.74 ? 19  HIS D CD2 1 
ATOM 137  C CE1 . HIS A 1 19  ? 137.551 108.695 48.931  1.00 122.74 ? 19  HIS D CE1 1 
ATOM 138  N NE2 . HIS A 1 19  ? 136.416 108.637 48.258  1.00 122.74 ? 19  HIS D NE2 1 
ATOM 139  N N   . PRO A 1 20  ? 136.635 107.388 53.107  1.00 117.75 ? 20  PRO D N   1 
ATOM 140  C CA  . PRO A 1 20  ? 137.813 106.892 53.841  1.00 117.75 ? 20  PRO D CA  1 
ATOM 141  C C   . PRO A 1 20  ? 139.106 107.608 53.492  1.00 117.75 ? 20  PRO D C   1 
ATOM 142  O O   . PRO A 1 20  ? 139.947 107.810 54.377  1.00 117.75 ? 20  PRO D O   1 
ATOM 143  C CB  . PRO A 1 20  ? 137.867 105.410 53.444  1.00 117.75 ? 20  PRO D CB  1 
ATOM 144  C CG  . PRO A 1 20  ? 136.463 105.069 53.096  1.00 117.75 ? 20  PRO D CG  1 
ATOM 145  C CD  . PRO A 1 20  ? 135.931 106.293 52.416  1.00 117.75 ? 20  PRO D CD  1 
ATOM 146  N N   . LYS A 1 21  ? 139.294 107.997 52.229  1.00 114.03 ? 21  LYS D N   1 
ATOM 147  C CA  . LYS A 1 21  ? 140.573 108.559 51.807  1.00 114.03 ? 21  LYS D CA  1 
ATOM 148  C C   . LYS A 1 21  ? 140.937 109.825 52.571  1.00 114.03 ? 21  LYS D C   1 
ATOM 149  O O   . LYS A 1 21  ? 142.126 110.139 52.691  1.00 114.03 ? 21  LYS D O   1 
ATOM 150  C CB  . LYS A 1 21  ? 140.544 108.854 50.306  1.00 114.03 ? 21  LYS D CB  1 
ATOM 151  C CG  . LYS A 1 21  ? 141.896 109.237 49.728  1.00 114.03 ? 21  LYS D CG  1 
ATOM 152  C CD  . LYS A 1 21  ? 141.872 109.228 48.209  1.00 114.03 ? 21  LYS D CD  1 
ATOM 153  C CE  . LYS A 1 21  ? 143.227 109.599 47.628  1.00 114.03 ? 21  LYS D CE  1 
ATOM 154  N NZ  . LYS A 1 21  ? 143.225 109.565 46.140  1.00 114.03 ? 21  LYS D NZ  1 
ATOM 155  N N   . ASN A 1 22  ? 139.953 110.555 53.087  1.00 119.57 ? 22  ASN D N   1 
ATOM 156  C CA  . ASN A 1 22  ? 140.200 111.801 53.800  1.00 119.57 ? 22  ASN D CA  1 
ATOM 157  C C   . ASN A 1 22  ? 140.340 111.609 55.305  1.00 119.57 ? 22  ASN D C   1 
ATOM 158  O O   . ASN A 1 22  ? 140.511 112.596 56.026  1.00 119.57 ? 22  ASN D O   1 
ATOM 159  C CB  . ASN A 1 22  ? 139.088 112.796 53.505  1.00 30.00  ? 22  ASN D CB  1 
ATOM 160  N N   . ILE A 1 23  ? 140.274 110.374 55.794  1.00 108.02 ? 23  ILE D N   1 
ATOM 161  C CA  . ILE A 1 23  ? 140.371 110.096 57.222  1.00 108.02 ? 23  ILE D CA  1 
ATOM 162  C C   . ILE A 1 23  ? 141.818 109.768 57.563  1.00 108.02 ? 23  ILE D C   1 
ATOM 163  O O   . ILE A 1 23  ? 142.426 108.883 56.950  1.00 108.02 ? 23  ILE D O   1 
ATOM 164  C CB  . ILE A 1 23  ? 139.435 108.944 57.624  1.00 108.02 ? 23  ILE D CB  1 
ATOM 165  C CG1 . ILE A 1 23  ? 137.984 109.298 57.287  1.00 108.02 ? 23  ILE D CG1 1 
ATOM 166  C CG2 . ILE A 1 23  ? 139.579 108.638 59.109  1.00 108.02 ? 23  ILE D CG2 1 
ATOM 167  C CD1 . ILE A 1 23  ? 137.015 108.148 57.459  1.00 108.02 ? 23  ILE D CD1 1 
ATOM 168  N N   . GLN A 1 24  ? 142.369 110.481 58.544  1.00 114.08 ? 24  GLN D N   1 
ATOM 169  C CA  . GLN A 1 24  ? 143.732 110.259 59.010  1.00 114.08 ? 24  GLN D CA  1 
ATOM 170  C C   . GLN A 1 24  ? 143.793 109.408 60.269  1.00 114.08 ? 24  GLN D C   1 
ATOM 171  O O   . GLN A 1 24  ? 144.639 108.514 60.365  1.00 114.08 ? 24  GLN D O   1 
ATOM 172  C CB  . GLN A 1 24  ? 144.425 111.599 59.275  1.00 114.08 ? 24  GLN D CB  1 
ATOM 173  C CG  . GLN A 1 24  ? 145.920 111.482 59.529  1.00 114.08 ? 24  GLN D CG  1 
ATOM 174  C CD  . GLN A 1 24  ? 146.562 112.817 59.845  1.00 114.08 ? 24  GLN D CD  1 
ATOM 175  O OE1 . GLN A 1 24  ? 145.971 113.659 60.521  1.00 114.08 ? 24  GLN D OE1 1 
ATOM 176  N NE2 . GLN A 1 24  ? 147.781 113.018 59.356  1.00 114.08 ? 24  GLN D NE2 1 
ATOM 177  N N   . SER A 1 25  ? 142.919 109.666 61.239  1.00 104.70 ? 25  SER D N   1 
ATOM 178  C CA  . SER A 1 25  ? 142.878 108.885 62.464  1.00 104.70 ? 25  SER D CA  1 
ATOM 179  C C   . SER A 1 25  ? 141.457 108.896 63.005  1.00 104.70 ? 25  SER D C   1 
ATOM 180  O O   . SER A 1 25  ? 140.675 109.805 62.714  1.00 104.70 ? 25  SER D O   1 
ATOM 181  C CB  . SER A 1 25  ? 143.851 109.431 63.515  1.00 104.70 ? 25  SER D CB  1 
ATOM 182  O OG  . SER A 1 25  ? 143.457 110.717 63.954  1.00 104.70 ? 25  SER D OG  1 
ATOM 183  N N   . VAL A 1 26  ? 141.132 107.875 63.792  1.00 83.63  ? 26  VAL D N   1 
ATOM 184  C CA  . VAL A 1 26  ? 139.817 107.734 64.402  1.00 83.63  ? 26  VAL D CA  1 
ATOM 185  C C   . VAL A 1 26  ? 140.002 107.374 65.867  1.00 83.63  ? 26  VAL D C   1 
ATOM 186  O O   . VAL A 1 26  ? 140.840 106.532 66.208  1.00 83.63  ? 26  VAL D O   1 
ATOM 187  C CB  . VAL A 1 26  ? 138.969 106.668 63.678  1.00 83.63  ? 26  VAL D CB  1 
ATOM 188  C CG1 . VAL A 1 26  ? 137.800 106.230 64.547  1.00 83.63  ? 26  VAL D CG1 1 
ATOM 189  C CG2 . VAL A 1 26  ? 138.476 107.206 62.349  1.00 83.63  ? 26  VAL D CG2 1 
ATOM 190  N N   . ASN A 1 27  ? 139.221 108.014 66.733  1.00 72.73  ? 27  ASN D N   1 
ATOM 191  C CA  . ASN A 1 27  ? 139.263 107.773 68.169  1.00 72.73  ? 27  ASN D CA  1 
ATOM 192  C C   . ASN A 1 27  ? 137.946 107.142 68.591  1.00 72.73  ? 27  ASN D C   1 
ATOM 193  O O   . ASN A 1 27  ? 136.878 107.717 68.357  1.00 72.73  ? 27  ASN D O   1 
ATOM 194  C CB  . ASN A 1 27  ? 139.505 109.073 68.937  1.00 72.73  ? 27  ASN D CB  1 
ATOM 195  C CG  . ASN A 1 27  ? 139.710 108.844 70.418  1.00 72.73  ? 27  ASN D CG  1 
ATOM 196  O OD1 . ASN A 1 27  ? 140.450 107.948 70.821  1.00 72.73  ? 27  ASN D OD1 1 
ATOM 197  N ND2 . ASN A 1 27  ? 139.050 109.651 71.240  1.00 72.73  ? 27  ASN D ND2 1 
ATOM 198  N N   . VAL A 1 28  ? 138.022 105.968 69.211  1.00 79.11  ? 28  VAL D N   1 
ATOM 199  C CA  . VAL A 1 28  ? 136.848 105.230 69.663  1.00 79.11  ? 28  VAL D CA  1 
ATOM 200  C C   . VAL A 1 28  ? 136.873 105.201 71.184  1.00 79.11  ? 28  VAL D C   1 
ATOM 201  O O   . VAL A 1 28  ? 137.798 104.642 71.786  1.00 79.11  ? 28  VAL D O   1 
ATOM 202  C CB  . VAL A 1 28  ? 136.816 103.808 69.085  1.00 79.11  ? 28  VAL D CB  1 
ATOM 203  C CG1 . VAL A 1 28  ? 135.508 103.122 69.442  1.00 79.11  ? 28  VAL D CG1 1 
ATOM 204  C CG2 . VAL A 1 28  ? 137.012 103.842 67.579  1.00 79.11  ? 28  VAL D CG2 1 
ATOM 205  N N   . LYS A 1 29  ? 135.861 105.799 71.803  1.00 81.33  ? 29  LYS D N   1 
ATOM 206  C CA  . LYS A 1 29  ? 135.743 105.856 73.253  1.00 81.33  ? 29  LYS D CA  1 
ATOM 207  C C   . LYS A 1 29  ? 134.535 105.043 73.693  1.00 81.33  ? 29  LYS D C   1 
ATOM 208  O O   . LYS A 1 29  ? 133.406 105.328 73.282  1.00 81.33  ? 29  LYS D O   1 
ATOM 209  C CB  . LYS A 1 29  ? 135.607 107.302 73.735  1.00 81.33  ? 29  LYS D CB  1 
ATOM 210  C CG  . LYS A 1 29  ? 136.753 108.207 73.310  1.00 81.33  ? 29  LYS D CG  1 
ATOM 211  C CD  . LYS A 1 29  ? 136.449 109.677 73.574  1.00 81.33  ? 29  LYS D CD  1 
ATOM 212  C CE  . LYS A 1 29  ? 136.368 109.989 75.062  1.00 81.33  ? 29  LYS D CE  1 
ATOM 213  N NZ  . LYS A 1 29  ? 135.692 111.290 75.319  1.00 81.33  ? 29  LYS D NZ  1 
ATOM 214  N N   . SER A 1 30  ? 134.776 104.039 74.527  1.00 79.00  ? 30  SER D N   1 
ATOM 215  C CA  . SER A 1 30  ? 133.699 103.230 75.066  1.00 79.00  ? 30  SER D CA  1 
ATOM 216  C C   . SER A 1 30  ? 132.930 104.015 76.122  1.00 79.00  ? 30  SER D C   1 
ATOM 217  O O   . SER A 1 30  ? 133.428 105.010 76.653  1.00 79.00  ? 30  SER D O   1 
ATOM 218  C CB  . SER A 1 30  ? 134.258 101.949 75.673  1.00 79.00  ? 30  SER D CB  1 
ATOM 219  O OG  . SER A 1 30  ? 135.095 102.235 76.780  1.00 79.00  ? 30  SER D OG  1 
ATOM 220  N N   . PRO A 1 31  ? 131.707 103.595 76.442  1.00 75.91  ? 31  PRO D N   1 
ATOM 221  C CA  . PRO A 1 31  ? 130.953 104.288 77.491  1.00 75.91  ? 31  PRO D CA  1 
ATOM 222  C C   . PRO A 1 31  ? 131.733 104.303 78.795  1.00 75.91  ? 31  PRO D C   1 
ATOM 223  O O   . PRO A 1 31  ? 132.381 103.322 79.165  1.00 75.91  ? 31  PRO D O   1 
ATOM 224  C CB  . PRO A 1 31  ? 129.668 103.461 77.605  1.00 75.91  ? 31  PRO D CB  1 
ATOM 225  C CG  . PRO A 1 31  ? 129.518 102.844 76.259  1.00 75.91  ? 31  PRO D CG  1 
ATOM 226  C CD  . PRO A 1 31  ? 130.920 102.503 75.845  1.00 75.91  ? 31  PRO D CD  1 
ATOM 227  N N   . GLY A 1 32  ? 131.667 105.432 79.493  1.00 66.54  ? 32  GLY D N   1 
ATOM 228  C CA  . GLY A 1 32  ? 132.448 105.622 80.689  1.00 66.54  ? 32  GLY D CA  1 
ATOM 229  C C   . GLY A 1 32  ? 131.862 106.671 81.610  1.00 66.54  ? 32  GLY D C   1 
ATOM 230  O O   . GLY A 1 32  ? 130.720 107.110 81.447  1.00 66.54  ? 32  GLY D O   1 
ATOM 231  N N   . PRO A 1 33  ? 132.643 107.094 82.606  1.00 70.26  ? 33  PRO D N   1 
ATOM 232  C CA  . PRO A 1 33  ? 132.120 108.059 83.587  1.00 70.26  ? 33  PRO D CA  1 
ATOM 233  C C   . PRO A 1 33  ? 131.744 109.400 82.988  1.00 70.26  ? 33  PRO D C   1 
ATOM 234  O O   . PRO A 1 33  ? 130.966 110.136 83.608  1.00 70.26  ? 33  PRO D O   1 
ATOM 235  C CB  . PRO A 1 33  ? 133.269 108.204 84.594  1.00 70.26  ? 33  PRO D CB  1 
ATOM 236  C CG  . PRO A 1 33  ? 134.478 107.688 83.907  1.00 70.26  ? 33  PRO D CG  1 
ATOM 237  C CD  . PRO A 1 33  ? 134.025 106.685 82.901  1.00 70.26  ? 33  PRO D CD  1 
ATOM 238  N N   . HIS A 1 34  ? 132.263 109.748 81.811  1.00 83.81  ? 34  HIS D N   1 
ATOM 239  C CA  . HIS A 1 34  ? 132.055 111.069 81.231  1.00 83.81  ? 34  HIS D CA  1 
ATOM 240  C C   . HIS A 1 34  ? 131.118 111.053 80.031  1.00 83.81  ? 34  HIS D C   1 
ATOM 241  O O   . HIS A 1 34  ? 130.918 112.099 79.405  1.00 83.81  ? 34  HIS D O   1 
ATOM 242  C CB  . HIS A 1 34  ? 133.397 111.683 80.825  1.00 83.81  ? 34  HIS D CB  1 
ATOM 243  C CG  . HIS A 1 34  ? 134.238 110.784 79.974  1.00 83.81  ? 34  HIS D CG  1 
ATOM 244  N ND1 . HIS A 1 34  ? 135.037 109.793 80.502  1.00 83.81  ? 34  HIS D ND1 1 
ATOM 245  C CD2 . HIS A 1 34  ? 134.402 110.724 78.632  1.00 83.81  ? 34  HIS D CD2 1 
ATOM 246  C CE1 . HIS A 1 34  ? 135.658 109.163 79.521  1.00 83.81  ? 34  HIS D CE1 1 
ATOM 247  N NE2 . HIS A 1 34  ? 135.290 109.708 78.376  1.00 83.81  ? 34  HIS D NE2 1 
ATOM 248  N N   . CYS A 1 35  ? 130.538 109.904 79.690  1.00 93.42  ? 35  CYS D N   1 
ATOM 249  C CA  . CYS A 1 35  ? 129.607 109.850 78.569  1.00 93.42  ? 35  CYS D CA  1 
ATOM 250  C C   . CYS A 1 35  ? 128.840 108.535 78.560  1.00 93.42  ? 35  CYS D C   1 
ATOM 251  O O   . CYS A 1 35  ? 129.424 107.465 78.761  1.00 93.42  ? 35  CYS D O   1 
ATOM 252  C CB  . CYS A 1 35  ? 130.351 110.036 77.245  1.00 93.42  ? 35  CYS D CB  1 
ATOM 253  S SG  . CYS A 1 35  ? 129.270 110.381 75.840  1.00 93.42  ? 35  CYS D SG  1 
ATOM 254  N N   . ALA A 1 36  ? 127.528 108.606 78.330  1.00 80.82  ? 36  ALA D N   1 
ATOM 255  C CA  . ALA A 1 36  ? 126.697 107.411 78.311  1.00 80.82  ? 36  ALA D CA  1 
ATOM 256  C C   . ALA A 1 36  ? 126.833 106.611 77.023  1.00 80.82  ? 36  ALA D C   1 
ATOM 257  O O   . ALA A 1 36  ? 126.772 105.378 77.069  1.00 80.82  ? 36  ALA D O   1 
ATOM 258  C CB  . ALA A 1 36  ? 125.229 107.790 78.517  1.00 80.82  ? 36  ALA D CB  1 
ATOM 259  N N   . GLN A 1 37  ? 127.017 107.275 75.886  1.00 97.93  ? 37  GLN D N   1 
ATOM 260  C CA  . GLN A 1 37  ? 127.030 106.618 74.588  1.00 97.93  ? 37  GLN D CA  1 
ATOM 261  C C   . GLN A 1 37  ? 128.447 106.535 74.037  1.00 97.93  ? 37  GLN D C   1 
ATOM 262  O O   . GLN A 1 37  ? 129.327 107.316 74.407  1.00 97.93  ? 37  GLN D O   1 
ATOM 263  C CB  . GLN A 1 37  ? 126.141 107.367 73.592  1.00 97.93  ? 37  GLN D CB  1 
ATOM 264  C CG  . GLN A 1 37  ? 124.729 107.630 74.082  1.00 97.93  ? 37  GLN D CG  1 
ATOM 265  C CD  . GLN A 1 37  ? 123.983 108.600 73.189  1.00 97.93  ? 37  GLN D CD  1 
ATOM 266  O OE1 . GLN A 1 37  ? 123.552 109.664 73.633  1.00 97.93  ? 37  GLN D OE1 1 
ATOM 267  N NE2 . GLN A 1 37  ? 123.831 108.239 71.920  1.00 97.93  ? 37  GLN D NE2 1 
ATOM 268  N N   . THR A 1 38  ? 128.657 105.574 73.142  1.00 94.03  ? 38  THR D N   1 
ATOM 269  C CA  . THR A 1 38  ? 129.933 105.458 72.453  1.00 94.03  ? 38  THR D CA  1 
ATOM 270  C C   . THR A 1 38  ? 130.125 106.634 71.503  1.00 94.03  ? 38  THR D C   1 
ATOM 271  O O   . THR A 1 38  ? 129.177 107.127 70.887  1.00 94.03  ? 38  THR D O   1 
ATOM 272  C CB  . THR A 1 38  ? 130.004 104.143 71.678  1.00 94.03  ? 38  THR D CB  1 
ATOM 273  O OG1 . THR A 1 38  ? 129.871 103.042 72.585  1.00 94.03  ? 38  THR D OG1 1 
ATOM 274  C CG2 . THR A 1 38  ? 131.328 104.023 70.938  1.00 94.03  ? 38  THR D CG2 1 
ATOM 275  N N   . GLU A 1 39  ? 131.373 107.085 71.388  1.00 84.95  ? 39  GLU D N   1 
ATOM 276  C CA  . GLU A 1 39  ? 131.720 108.233 70.559  1.00 84.95  ? 39  GLU D CA  1 
ATOM 277  C C   . GLU A 1 39  ? 132.869 107.851 69.642  1.00 84.95  ? 39  GLU D C   1 
ATOM 278  O O   . GLU A 1 39  ? 133.922 107.409 70.114  1.00 84.95  ? 39  GLU D O   1 
ATOM 279  C CB  . GLU A 1 39  ? 132.105 109.437 71.423  1.00 84.95  ? 39  GLU D CB  1 
ATOM 280  C CG  . GLU A 1 39  ? 130.960 109.992 72.249  1.00 84.95  ? 39  GLU D CG  1 
ATOM 281  C CD  . GLU A 1 39  ? 131.284 111.340 72.858  1.00 84.95  ? 39  GLU D CD  1 
ATOM 282  O OE1 . GLU A 1 39  ? 132.179 111.401 73.727  1.00 84.95  ? 39  GLU D OE1 1 
ATOM 283  O OE2 . GLU A 1 39  ? 130.646 112.340 72.467  1.00 84.95  ? 39  GLU D OE2 1 
ATOM 284  N N   . VAL A 1 40  ? 132.668 108.021 68.340  1.00 83.38  ? 40  VAL D N   1 
ATOM 285  C CA  . VAL A 1 40  ? 133.701 107.791 67.338  1.00 83.38  ? 40  VAL D CA  1 
ATOM 286  C C   . VAL A 1 40  ? 133.996 109.132 66.684  1.00 83.38  ? 40  VAL D C   1 
ATOM 287  O O   . VAL A 1 40  ? 133.139 109.701 65.996  1.00 83.38  ? 40  VAL D O   1 
ATOM 288  C CB  . VAL A 1 40  ? 133.270 106.746 66.300  1.00 83.38  ? 40  VAL D CB  1 
ATOM 289  C CG1 . VAL A 1 40  ? 134.395 106.481 65.313  1.00 83.38  ? 40  VAL D CG1 1 
ATOM 290  C CG2 . VAL A 1 40  ? 132.846 105.461 66.991  1.00 83.38  ? 40  VAL D CG2 1 
ATOM 291  N N   . ILE A 1 41  ? 135.208 109.638 66.893  1.00 76.47  ? 41  ILE D N   1 
ATOM 292  C CA  . ILE A 1 41  ? 135.630 110.940 66.387  1.00 76.47  ? 41  ILE D CA  1 
ATOM 293  C C   . ILE A 1 41  ? 136.726 110.710 65.359  1.00 76.47  ? 41  ILE D C   1 
ATOM 294  O O   . ILE A 1 41  ? 137.714 110.019 65.638  1.00 76.47  ? 41  ILE D O   1 
ATOM 295  C CB  . ILE A 1 41  ? 136.118 111.856 67.519  1.00 76.47  ? 41  ILE D CB  1 
ATOM 296  C CG1 . ILE A 1 41  ? 134.992 112.116 68.519  1.00 76.47  ? 41  ILE D CG1 1 
ATOM 297  C CG2 . ILE A 1 41  ? 136.631 113.167 66.954  1.00 76.47  ? 41  ILE D CG2 1 
ATOM 298  C CD1 . ILE A 1 41  ? 135.479 112.379 69.924  1.00 76.47  ? 41  ILE D CD1 1 
ATOM 299  N N   . ALA A 1 42  ? 136.555 111.287 64.174  1.00 87.17  ? 42  ALA D N   1 
ATOM 300  C CA  . ALA A 1 42  ? 137.500 111.128 63.078  1.00 87.17  ? 42  ALA D CA  1 
ATOM 301  C C   . ALA A 1 42  ? 138.270 112.424 62.873  1.00 87.17  ? 42  ALA D C   1 
ATOM 302  O O   . ALA A 1 42  ? 137.670 113.498 62.763  1.00 87.17  ? 42  ALA D O   1 
ATOM 303  C CB  . ALA A 1 42  ? 136.776 110.735 61.790  1.00 87.17  ? 42  ALA D CB  1 
ATOM 304  N N   . THR A 1 43  ? 139.596 112.320 62.824  1.00 102.32 ? 43  THR D N   1 
ATOM 305  C CA  . THR A 1 43  ? 140.470 113.455 62.560  1.00 102.32 ? 43  THR D CA  1 
ATOM 306  C C   . THR A 1 43  ? 140.861 113.432 61.088  1.00 102.32 ? 43  THR D C   1 
ATOM 307  O O   . THR A 1 43  ? 141.601 112.543 60.652  1.00 102.32 ? 43  THR D O   1 
ATOM 308  C CB  . THR A 1 43  ? 141.713 113.409 63.448  1.00 102.32 ? 43  THR D CB  1 
ATOM 309  O OG1 . THR A 1 43  ? 141.318 113.335 64.824  1.00 102.32 ? 43  THR D OG1 1 
ATOM 310  C CG2 . THR A 1 43  ? 142.570 114.649 63.238  1.00 102.32 ? 43  THR D CG2 1 
ATOM 311  N N   . LEU A 1 44  ? 140.368 114.404 60.331  1.00 111.68 ? 44  LEU D N   1 
ATOM 312  C CA  . LEU A 1 44  ? 140.565 114.438 58.891  1.00 111.68 ? 44  LEU D CA  1 
ATOM 313  C C   . LEU A 1 44  ? 141.986 114.872 58.546  1.00 111.68 ? 44  LEU D C   1 
ATOM 314  O O   . LEU A 1 44  ? 142.733 115.376 59.387  1.00 111.68 ? 44  LEU D O   1 
ATOM 315  C CB  . LEU A 1 44  ? 139.557 115.384 58.238  1.00 111.68 ? 44  LEU D CB  1 
ATOM 316  C CG  . LEU A 1 44  ? 138.087 115.053 58.497  1.00 111.68 ? 44  LEU D CG  1 
ATOM 317  C CD1 . LEU A 1 44  ? 137.189 116.124 57.907  1.00 111.68 ? 44  LEU D CD1 1 
ATOM 318  C CD2 . LEU A 1 44  ? 137.734 113.689 57.930  1.00 111.68 ? 44  LEU D CD2 1 
ATOM 319  N N   . LYS A 1 45  ? 142.351 114.664 57.279  1.00 115.75 ? 45  LYS D N   1 
ATOM 320  C CA  . LYS A 1 45  ? 143.682 115.035 56.815  1.00 115.75 ? 45  LYS D CA  1 
ATOM 321  C C   . LYS A 1 45  ? 143.913 116.539 56.861  1.00 115.75 ? 45  LYS D C   1 
ATOM 322  O O   . LYS A 1 45  ? 145.069 116.977 56.888  1.00 115.75 ? 45  LYS D O   1 
ATOM 323  C CB  . LYS A 1 45  ? 143.897 114.525 55.389  1.00 115.75 ? 45  LYS D CB  1 
ATOM 324  C CG  . LYS A 1 45  ? 144.112 113.025 55.291  1.00 115.75 ? 45  LYS D CG  1 
ATOM 325  C CD  . LYS A 1 45  ? 144.526 112.618 53.886  1.00 115.75 ? 45  LYS D CD  1 
ATOM 326  C CE  . LYS A 1 45  ? 144.855 111.137 53.809  1.00 115.75 ? 45  LYS D CE  1 
ATOM 327  N NZ  . LYS A 1 45  ? 145.062 110.685 52.406  1.00 115.75 ? 45  LYS D NZ  1 
ATOM 328  N N   . ASN A 1 46  ? 142.847 117.337 56.874  1.00 122.34 ? 46  ASN D N   1 
ATOM 329  C CA  . ASN A 1 46  ? 142.952 118.789 56.865  1.00 122.34 ? 46  ASN D CA  1 
ATOM 330  C C   . ASN A 1 46  ? 142.968 119.387 58.266  1.00 122.34 ? 46  ASN D C   1 
ATOM 331  O O   . ASN A 1 46  ? 142.957 120.614 58.404  1.00 122.34 ? 46  ASN D O   1 
ATOM 332  C CB  . ASN A 1 46  ? 141.802 119.390 56.052  1.00 122.34 ? 46  ASN D CB  1 
ATOM 333  C CG  . ASN A 1 46  ? 140.438 119.046 56.622  1.00 122.34 ? 46  ASN D CG  1 
ATOM 334  O OD1 . ASN A 1 46  ? 140.329 118.503 57.721  1.00 122.34 ? 46  ASN D OD1 1 
ATOM 335  N ND2 . ASN A 1 46  ? 139.389 119.356 55.870  1.00 122.34 ? 46  ASN D ND2 1 
ATOM 336  N N   . GLY A 1 47  ? 142.993 118.553 59.305  1.00 112.40 ? 47  GLY D N   1 
ATOM 337  C CA  . GLY A 1 47  ? 143.003 119.026 60.672  1.00 112.40 ? 47  GLY D CA  1 
ATOM 338  C C   . GLY A 1 47  ? 141.641 119.188 61.307  1.00 112.40 ? 47  GLY D C   1 
ATOM 339  O O   . GLY A 1 47  ? 141.568 119.465 62.511  1.00 112.40 ? 47  GLY D O   1 
ATOM 340  N N   . ARG A 1 48  ? 140.560 119.028 60.549  1.00 118.30 ? 48  ARG D N   1 
ATOM 341  C CA  . ARG A 1 48  ? 139.222 119.128 61.108  1.00 118.30 ? 48  ARG D CA  1 
ATOM 342  C C   . ARG A 1 48  ? 138.812 117.810 61.752  1.00 118.30 ? 48  ARG D C   1 
ATOM 343  O O   . ARG A 1 48  ? 139.164 116.725 61.281  1.00 118.30 ? 48  ARG D O   1 
ATOM 344  C CB  . ARG A 1 48  ? 138.212 119.509 60.026  1.00 118.30 ? 48  ARG D CB  1 
ATOM 345  C CG  . ARG A 1 48  ? 138.443 120.878 59.411  1.00 118.30 ? 48  ARG D CG  1 
ATOM 346  C CD  . ARG A 1 48  ? 137.474 121.138 58.270  1.00 118.30 ? 48  ARG D CD  1 
ATOM 347  N NE  . ARG A 1 48  ? 136.085 121.069 58.708  1.00 118.30 ? 48  ARG D NE  1 
ATOM 348  C CZ  . ARG A 1 48  ? 135.060 120.769 57.921  1.00 118.30 ? 48  ARG D CZ  1 
ATOM 349  N NH1 . ARG A 1 48  ? 135.226 120.506 56.634  1.00 118.30 ? 48  ARG D NH1 1 
ATOM 350  N NH2 . ARG A 1 48  ? 133.835 120.733 58.438  1.00 118.30 ? 48  ARG D NH2 1 
ATOM 351  N N   . LYS A 1 49  ? 138.057 117.916 62.841  1.00 103.81 ? 49  LYS D N   1 
ATOM 352  C CA  . LYS A 1 49  ? 137.538 116.764 63.559  1.00 103.81 ? 49  LYS D CA  1 
ATOM 353  C C   . LYS A 1 49  ? 136.044 116.628 63.297  1.00 103.81 ? 49  LYS D C   1 
ATOM 354  O O   . LYS A 1 49  ? 135.292 117.602 63.383  1.00 103.81 ? 49  LYS D O   1 
ATOM 355  C CB  . LYS A 1 49  ? 137.794 116.891 65.063  1.00 103.81 ? 49  LYS D CB  1 
ATOM 356  C CG  . LYS A 1 49  ? 139.264 116.928 65.441  1.00 103.81 ? 49  LYS D CG  1 
ATOM 357  C CD  . LYS A 1 49  ? 139.456 116.752 66.939  1.00 103.81 ? 49  LYS D CD  1 
ATOM 358  C CE  . LYS A 1 49  ? 140.928 116.665 67.307  1.00 103.81 ? 49  LYS D CE  1 
ATOM 359  N NZ  . LYS A 1 49  ? 141.132 116.618 68.781  1.00 103.81 ? 49  LYS D NZ  1 
ATOM 360  N N   . ALA A 1 50  ? 135.622 115.408 62.972  1.00 103.77 ? 50  ALA D N   1 
ATOM 361  C CA  . ALA A 1 50  ? 134.232 115.130 62.649  1.00 103.77 ? 50  ALA D CA  1 
ATOM 362  C C   . ALA A 1 50  ? 133.758 113.926 63.448  1.00 103.77 ? 50  ALA D C   1 
ATOM 363  O O   . ALA A 1 50  ? 134.538 113.027 63.769  1.00 103.77 ? 50  ALA D O   1 
ATOM 364  C CB  . ALA A 1 50  ? 134.042 114.869 61.150  1.00 103.77 ? 50  ALA D CB  1 
ATOM 365  N N   . CYS A 1 51  ? 132.467 113.922 63.766  1.00 100.38 ? 51  CYS D N   1 
ATOM 366  C CA  . CYS A 1 51  ? 131.849 112.825 64.498  1.00 100.38 ? 51  CYS D CA  1 
ATOM 367  C C   . CYS A 1 51  ? 131.383 111.746 63.531  1.00 100.38 ? 51  CYS D C   1 
ATOM 368  O O   . CYS A 1 51  ? 131.052 112.034 62.377  1.00 100.38 ? 51  CYS D O   1 
ATOM 369  C CB  . CYS A 1 51  ? 130.665 113.325 65.323  1.00 100.38 ? 51  CYS D CB  1 
ATOM 370  S SG  . CYS A 1 51  ? 131.073 113.865 66.993  1.00 100.38 ? 51  CYS D SG  1 
ATOM 371  N N   . LEU A 1 52  ? 131.358 110.507 64.010  1.00 96.40  ? 52  LEU D N   1 
ATOM 372  C CA  . LEU A 1 52  ? 130.832 109.375 63.265  1.00 96.40  ? 52  LEU D CA  1 
ATOM 373  C C   . LEU A 1 52  ? 129.878 108.584 64.151  1.00 96.40  ? 52  LEU D C   1 
ATOM 374  O O   . LEU A 1 52  ? 130.069 108.488 65.366  1.00 96.40  ? 52  LEU D O   1 
ATOM 375  C CB  . LEU A 1 52  ? 131.964 108.469 62.769  1.00 96.40  ? 52  LEU D CB  1 
ATOM 376  C CG  . LEU A 1 52  ? 132.963 109.111 61.804  1.00 96.40  ? 52  LEU D CG  1 
ATOM 377  C CD1 . LEU A 1 52  ? 134.061 108.128 61.444  1.00 96.40  ? 52  LEU D CD1 1 
ATOM 378  C CD2 . LEU A 1 52  ? 132.263 109.601 60.549  1.00 96.40  ? 52  LEU D CD2 1 
ATOM 379  N N   . ASN A 1 53  ? 128.846 108.022 63.534  1.00 97.57  ? 53  ASN D N   1 
ATOM 380  C CA  . ASN A 1 53  ? 127.831 107.293 64.283  1.00 97.57  ? 53  ASN D CA  1 
ATOM 381  C C   . ASN A 1 53  ? 128.309 105.870 64.551  1.00 97.57  ? 53  ASN D C   1 
ATOM 382  O O   . ASN A 1 53  ? 128.555 105.123 63.597  1.00 97.57  ? 53  ASN D O   1 
ATOM 383  C CB  . ASN A 1 53  ? 126.520 107.270 63.510  1.00 97.57  ? 53  ASN D CB  1 
ATOM 384  C CG  . ASN A 1 53  ? 125.424 106.517 64.238  1.00 97.57  ? 53  ASN D CG  1 
ATOM 385  O OD1 . ASN A 1 53  ? 125.586 106.118 65.391  1.00 97.57  ? 53  ASN D OD1 1 
ATOM 386  N ND2 . ASN A 1 53  ? 124.296 106.320 63.565  1.00 97.57  ? 53  ASN D ND2 1 
ATOM 387  N N   . PRO A 1 54  ? 128.455 105.452 65.813  1.00 93.18  ? 54  PRO D N   1 
ATOM 388  C CA  . PRO A 1 54  ? 128.915 104.073 66.061  1.00 93.18  ? 54  PRO D CA  1 
ATOM 389  C C   . PRO A 1 54  ? 127.979 103.017 65.497  1.00 93.18  ? 54  PRO D C   1 
ATOM 390  O O   . PRO A 1 54  ? 128.438 101.960 65.046  1.00 93.18  ? 54  PRO D O   1 
ATOM 391  C CB  . PRO A 1 54  ? 129.008 104.011 67.592  1.00 93.18  ? 54  PRO D CB  1 
ATOM 392  C CG  . PRO A 1 54  ? 128.077 105.066 68.071  1.00 93.18  ? 54  PRO D CG  1 
ATOM 393  C CD  . PRO A 1 54  ? 128.186 106.171 67.070  1.00 93.18  ? 54  PRO D CD  1 
ATOM 394  N N   . ALA A 1 55  ? 126.671 103.274 65.509  1.00 96.02  ? 55  ALA D N   1 
ATOM 395  C CA  . ALA A 1 55  ? 125.712 102.290 65.022  1.00 96.02  ? 55  ALA D CA  1 
ATOM 396  C C   . ALA A 1 55  ? 125.677 102.202 63.503  1.00 96.02  ? 55  ALA D C   1 
ATOM 397  O O   . ALA A 1 55  ? 125.059 101.274 62.969  1.00 96.02  ? 55  ALA D O   1 
ATOM 398  C CB  . ALA A 1 55  ? 124.314 102.620 65.549  1.00 96.02  ? 55  ALA D CB  1 
ATOM 399  N N   . SER A 1 56  ? 126.310 103.130 62.801  1.00 104.09 ? 56  SER D N   1 
ATOM 400  C CA  . SER A 1 56  ? 126.274 103.110 61.345  1.00 104.09 ? 56  SER D CA  1 
ATOM 401  C C   . SER A 1 56  ? 127.025 101.889 60.823  1.00 104.09 ? 56  SER D C   1 
ATOM 402  O O   . SER A 1 56  ? 128.167 101.652 61.233  1.00 104.09 ? 56  SER D O   1 
ATOM 403  C CB  . SER A 1 56  ? 126.891 104.386 60.780  1.00 104.09 ? 56  SER D CB  1 
ATOM 404  O OG  . SER A 1 56  ? 127.047 104.296 59.375  1.00 104.09 ? 56  SER D OG  1 
ATOM 405  N N   . PRO A 1 57  ? 126.430 101.093 59.930  1.00 101.26 ? 57  PRO D N   1 
ATOM 406  C CA  . PRO A 1 57  ? 127.188 99.973  59.346  1.00 101.26 ? 57  PRO D CA  1 
ATOM 407  C C   . PRO A 1 57  ? 128.471 100.412 58.660  1.00 101.26 ? 57  PRO D C   1 
ATOM 408  O O   . PRO A 1 57  ? 129.483 99.703  58.720  1.00 101.26 ? 57  PRO D O   1 
ATOM 409  C CB  . PRO A 1 57  ? 126.184 99.362  58.361  1.00 101.26 ? 57  PRO D CB  1 
ATOM 410  C CG  . PRO A 1 57  ? 124.857 99.687  58.934  1.00 101.26 ? 57  PRO D CG  1 
ATOM 411  C CD  . PRO A 1 57  ? 125.008 101.051 59.543  1.00 101.26 ? 57  PRO D CD  1 
ATOM 412  N N   . ILE A 1 58  ? 128.453 101.574 58.003  1.00 104.33 ? 58  ILE D N   1 
ATOM 413  C CA  . ILE A 1 58  ? 129.635 102.042 57.285  1.00 104.33 ? 58  ILE D CA  1 
ATOM 414  C C   . ILE A 1 58  ? 130.774 102.326 58.256  1.00 104.33 ? 58  ILE D C   1 
ATOM 415  O O   . ILE A 1 58  ? 131.936 102.001 57.984  1.00 104.33 ? 58  ILE D O   1 
ATOM 416  C CB  . ILE A 1 58  ? 129.289 103.283 56.442  1.00 104.33 ? 58  ILE D CB  1 
ATOM 417  C CG1 . ILE A 1 58  ? 128.340 102.902 55.303  1.00 104.33 ? 58  ILE D CG1 1 
ATOM 418  C CG2 . ILE A 1 58  ? 130.557 103.917 55.890  1.00 104.33 ? 58  ILE D CG2 1 
ATOM 419  C CD1 . ILE A 1 58  ? 127.681 104.087 54.629  1.00 104.33 ? 58  ILE D CD1 1 
ATOM 420  N N   . VAL A 1 59  ? 130.462 102.939 59.400  1.00 102.66 ? 59  VAL D N   1 
ATOM 421  C CA  . VAL A 1 59  ? 131.509 103.345 60.333  1.00 102.66 ? 59  VAL D CA  1 
ATOM 422  C C   . VAL A 1 59  ? 132.320 102.139 60.789  1.00 102.66 ? 59  VAL D C   1 
ATOM 423  O O   . VAL A 1 59  ? 133.554 102.192 60.849  1.00 102.66 ? 59  VAL D O   1 
ATOM 424  C CB  . VAL A 1 59  ? 130.892 104.098 61.525  1.00 102.66 ? 59  VAL D CB  1 
ATOM 425  C CG1 . VAL A 1 59  ? 131.892 104.200 62.668  1.00 102.66 ? 59  VAL D CG1 1 
ATOM 426  C CG2 . VAL A 1 59  ? 130.432 105.480 61.092  1.00 102.66 ? 59  VAL D CG2 1 
ATOM 427  N N   . LYS A 1 60  ? 131.648 101.034 61.120  1.00 108.21 ? 60  LYS D N   1 
ATOM 428  C CA  . LYS A 1 60  ? 132.369 99.838  61.538  1.00 108.21 ? 60  LYS D CA  1 
ATOM 429  C C   . LYS A 1 60  ? 133.290 99.342  60.431  1.00 108.21 ? 60  LYS D C   1 
ATOM 430  O O   . LYS A 1 60  ? 134.427 98.933  60.693  1.00 108.21 ? 60  LYS D O   1 
ATOM 431  C CB  . LYS A 1 60  ? 131.379 98.745  61.946  1.00 108.21 ? 60  LYS D CB  1 
ATOM 432  C CG  . LYS A 1 60  ? 132.027 97.455  62.435  1.00 108.21 ? 60  LYS D CG  1 
ATOM 433  C CD  . LYS A 1 60  ? 131.015 96.324  62.521  1.00 108.21 ? 60  LYS D CD  1 
ATOM 434  C CE  . LYS A 1 60  ? 131.603 95.098  63.202  1.00 108.21 ? 60  LYS D CE  1 
ATOM 435  N NZ  . LYS A 1 60  ? 131.690 95.264  64.680  1.00 108.21 ? 60  LYS D NZ  1 
ATOM 436  N N   . LYS A 1 61  ? 132.815 99.371  59.184  1.00 111.70 ? 61  LYS D N   1 
ATOM 437  C CA  . LYS A 1 61  ? 133.641 98.922  58.069  1.00 111.70 ? 61  LYS D CA  1 
ATOM 438  C C   . LYS A 1 61  ? 134.872 99.804  57.901  1.00 111.70 ? 61  LYS D C   1 
ATOM 439  O O   . LYS A 1 61  ? 135.965 99.306  57.605  1.00 111.70 ? 61  LYS D O   1 
ATOM 440  C CB  . LYS A 1 61  ? 132.815 98.905  56.783  1.00 111.70 ? 61  LYS D CB  1 
ATOM 441  C CG  . LYS A 1 61  ? 131.684 97.891  56.792  1.00 111.70 ? 61  LYS D CG  1 
ATOM 442  C CD  . LYS A 1 61  ? 130.788 98.042  55.574  1.00 111.70 ? 61  LYS D CD  1 
ATOM 443  C CE  . LYS A 1 61  ? 129.661 97.023  55.589  1.00 111.70 ? 61  LYS D CE  1 
ATOM 444  N NZ  . LYS A 1 61  ? 128.747 97.180  54.425  1.00 111.70 ? 61  LYS D NZ  1 
ATOM 445  N N   . ILE A 1 62  ? 134.715 101.116 58.083  1.00 108.34 ? 62  ILE D N   1 
ATOM 446  C CA  . ILE A 1 62  ? 135.829 102.032 57.861  1.00 108.34 ? 62  ILE D CA  1 
ATOM 447  C C   . ILE A 1 62  ? 136.975 101.728 58.818  1.00 108.34 ? 62  ILE D C   1 
ATOM 448  O O   . ILE A 1 62  ? 138.140 101.664 58.409  1.00 108.34 ? 62  ILE D O   1 
ATOM 449  C CB  . ILE A 1 62  ? 135.353 103.489 57.995  1.00 108.34 ? 62  ILE D CB  1 
ATOM 450  C CG1 . ILE A 1 62  ? 134.492 103.874 56.791  1.00 108.34 ? 62  ILE D CG1 1 
ATOM 451  C CG2 . ILE A 1 62  ? 136.544 104.429 58.122  1.00 108.34 ? 62  ILE D CG2 1 
ATOM 452  C CD1 . ILE A 1 62  ? 133.652 105.112 57.008  1.00 108.34 ? 62  ILE D CD1 1 
ATOM 453  N N   . ILE A 1 63  ? 136.668 101.534 60.102  1.00 97.83  ? 63  ILE D N   1 
ATOM 454  C CA  . ILE A 1 63  ? 137.718 101.240 61.073  1.00 97.83  ? 63  ILE D CA  1 
ATOM 455  C C   . ILE A 1 63  ? 138.417 99.937  60.712  1.00 97.83  ? 63  ILE D C   1 
ATOM 456  O O   . ILE A 1 63  ? 139.640 99.811  60.854  1.00 97.83  ? 63  ILE D O   1 
ATOM 457  C CB  . ILE A 1 63  ? 137.132 101.201 62.497  1.00 97.83  ? 63  ILE D CB  1 
ATOM 458  C CG1 . ILE A 1 63  ? 136.474 102.546 62.819  1.00 97.83  ? 63  ILE D CG1 1 
ATOM 459  C CG2 . ILE A 1 63  ? 138.221 100.874 63.519  1.00 97.83  ? 63  ILE D CG2 1 
ATOM 460  C CD1 . ILE A 1 63  ? 136.307 102.832 64.299  1.00 97.83  ? 63  ILE D CD1 1 
ATOM 461  N N   . GLU A 1 64  ? 137.657 98.948  60.240  1.00 111.07 ? 64  GLU D N   1 
ATOM 462  C CA  . GLU A 1 64  ? 138.263 97.692  59.811  1.00 111.07 ? 64  GLU D CA  1 
ATOM 463  C C   . GLU A 1 64  ? 139.221 97.922  58.650  1.00 111.07 ? 64  GLU D C   1 
ATOM 464  O O   . GLU A 1 64  ? 140.286 97.298  58.572  1.00 111.07 ? 64  GLU D O   1 
ATOM 465  C CB  . GLU A 1 64  ? 137.173 96.693  59.420  1.00 111.07 ? 64  GLU D CB  1 
ATOM 466  C CG  . GLU A 1 64  ? 136.468 96.047  60.607  1.00 111.07 ? 64  GLU D CG  1 
ATOM 467  C CD  . GLU A 1 64  ? 135.945 94.654  60.300  1.00 111.07 ? 64  GLU D CD  1 
ATOM 468  O OE1 . GLU A 1 64  ? 136.164 94.162  59.173  1.00 111.07 ? 64  GLU D OE1 1 
ATOM 469  O OE2 . GLU A 1 64  ? 135.312 94.049  61.191  1.00 111.07 ? 64  GLU D OE2 1 
ATOM 470  N N   . LYS A 1 65  ? 138.857 98.819  57.732  1.00 114.62 ? 65  LYS D N   1 
ATOM 471  C CA  . LYS A 1 65  ? 139.709 99.094  56.580  1.00 114.62 ? 65  LYS D CA  1 
ATOM 472  C C   . LYS A 1 65  ? 141.059 99.653  57.016  1.00 114.62 ? 65  LYS D C   1 
ATOM 473  O O   . LYS A 1 65  ? 142.109 99.245  56.505  1.00 114.62 ? 65  LYS D O   1 
ATOM 474  C CB  . LYS A 1 65  ? 139.003 100.066 55.635  1.00 114.62 ? 65  LYS D CB  1 
ATOM 475  C CG  . LYS A 1 65  ? 139.748 100.326 54.335  1.00 114.62 ? 65  LYS D CG  1 
ATOM 476  C CD  . LYS A 1 65  ? 138.793 100.711 53.211  1.00 114.62 ? 65  LYS D CD  1 
ATOM 477  C CE  . LYS A 1 65  ? 139.417 100.520 51.836  1.00 114.62 ? 65  LYS D CE  1 
ATOM 478  N NZ  . LYS A 1 65  ? 139.898 99.129  51.605  1.00 114.62 ? 65  LYS D NZ  1 
ATOM 479  N N   . MET A 1 66  ? 141.051 100.593 57.963  1.00 107.03 ? 66  MET D N   1 
ATOM 480  C CA  . MET A 1 66  ? 142.298 101.201 58.415  1.00 107.03 ? 66  MET D CA  1 
ATOM 481  C C   . MET A 1 66  ? 143.195 100.174 59.095  1.00 107.03 ? 66  MET D C   1 
ATOM 482  O O   . MET A 1 66  ? 144.417 100.175 58.906  1.00 107.03 ? 66  MET D O   1 
ATOM 483  C CB  . MET A 1 66  ? 142.000 102.360 59.366  1.00 107.03 ? 66  MET D CB  1 
ATOM 484  C CG  . MET A 1 66  ? 142.026 103.726 58.706  1.00 107.03 ? 66  MET D CG  1 
ATOM 485  S SD  . MET A 1 66  ? 141.947 105.063 59.909  1.00 107.03 ? 66  MET D SD  1 
ATOM 486  C CE  . MET A 1 66  ? 140.210 105.025 60.336  1.00 107.03 ? 66  MET D CE  1 
ATOM 487  N N   . LEU A 1 67  ? 142.602 99.285  59.894  1.00 97.69  ? 67  LEU D N   1 
ATOM 488  C CA  . LEU A 1 67  ? 143.400 98.342  60.669  1.00 97.69  ? 67  LEU D CA  1 
ATOM 489  C C   . LEU A 1 67  ? 144.067 97.300  59.780  1.00 97.69  ? 67  LEU D C   1 
ATOM 490  O O   . LEU A 1 67  ? 144.887 96.512  60.265  1.00 97.69  ? 67  LEU D O   1 
ATOM 491  C CB  . LEU A 1 67  ? 142.523 97.662  61.720  1.00 97.69  ? 67  LEU D CB  1 
ATOM 492  C CG  . LEU A 1 67  ? 141.983 98.591  62.808  1.00 97.69  ? 67  LEU D CG  1 
ATOM 493  C CD1 . LEU A 1 67  ? 140.936 97.883  63.653  1.00 97.69  ? 67  LEU D CD1 1 
ATOM 494  C CD2 . LEU A 1 67  ? 143.113 99.116  63.681  1.00 97.69  ? 67  LEU D CD2 1 
ATOM 495  N N   . ASN A 1 68  ? 143.718 97.266  58.496  1.00 123.53 ? 68  ASN D N   1 
ATOM 496  C CA  . ASN A 1 68  ? 144.312 96.329  57.545  1.00 123.53 ? 68  ASN D CA  1 
ATOM 497  C C   . ASN A 1 68  ? 145.813 96.168  57.762  1.00 123.53 ? 68  ASN D C   1 
ATOM 498  O O   . ASN A 1 68  ? 146.619 96.817  57.096  1.00 123.53 ? 68  ASN D O   1 
ATOM 499  C CB  . ASN A 1 68  ? 144.053 96.796  56.110  1.00 123.53 ? 68  ASN D CB  1 
ATOM 500  C CG  . ASN A 1 68  ? 142.689 96.383  55.598  1.00 123.53 ? 68  ASN D CG  1 
ATOM 501  O OD1 . ASN A 1 68  ? 141.930 95.704  56.290  1.00 123.53 ? 68  ASN D OD1 1 
ATOM 502  N ND2 . ASN A 1 68  ? 142.369 96.792  54.375  1.00 123.53 ? 68  ASN D ND2 1 
ATOM 503  N N   . CYS B 1 9   ? 157.729 106.732 64.943  1.00 149.83 ? 9   CYS E N   1 
ATOM 504  C CA  . CYS B 1 9   ? 156.417 106.130 65.315  1.00 149.83 ? 9   CYS E CA  1 
ATOM 505  C C   . CYS B 1 9   ? 156.326 105.941 66.825  1.00 149.83 ? 9   CYS E C   1 
ATOM 506  O O   . CYS B 1 9   ? 157.198 105.326 67.437  1.00 149.83 ? 9   CYS E O   1 
ATOM 507  C CB  . CYS B 1 9   ? 156.219 104.793 64.598  1.00 149.83 ? 9   CYS E CB  1 
ATOM 508  S SG  . CYS B 1 9   ? 156.315 104.901 62.795  1.00 149.83 ? 9   CYS E SG  1 
ATOM 509  N N   . GLN B 1 10  ? 155.259 106.476 67.422  1.00 134.97 ? 10  GLN E N   1 
ATOM 510  C CA  . GLN B 1 10  ? 155.110 106.421 68.871  1.00 134.97 ? 10  GLN E CA  1 
ATOM 511  C C   . GLN B 1 10  ? 154.972 104.993 69.383  1.00 134.97 ? 10  GLN E C   1 
ATOM 512  O O   . GLN B 1 10  ? 155.217 104.745 70.569  1.00 134.97 ? 10  GLN E O   1 
ATOM 513  C CB  . GLN B 1 10  ? 153.899 107.257 69.296  1.00 134.97 ? 10  GLN E CB  1 
ATOM 514  C CG  . GLN B 1 10  ? 153.427 107.014 70.722  1.00 134.97 ? 10  GLN E CG  1 
ATOM 515  C CD  . GLN B 1 10  ? 152.326 107.968 71.138  1.00 134.97 ? 10  GLN E CD  1 
ATOM 516  O OE1 . GLN B 1 10  ? 151.944 108.861 70.382  1.00 134.97 ? 10  GLN E OE1 1 
ATOM 517  N NE2 . GLN B 1 10  ? 151.809 107.785 72.348  1.00 134.97 ? 10  GLN E NE2 1 
ATOM 518  N N   . CYS B 1 11  ? 154.592 104.051 68.524  1.00 141.34 ? 11  CYS E N   1 
ATOM 519  C CA  . CYS B 1 11  ? 154.441 102.646 68.897  1.00 141.34 ? 11  CYS E CA  1 
ATOM 520  C C   . CYS B 1 11  ? 155.621 101.876 68.315  1.00 141.34 ? 11  CYS E C   1 
ATOM 521  O O   . CYS B 1 11  ? 155.676 101.624 67.108  1.00 141.34 ? 11  CYS E O   1 
ATOM 522  C CB  . CYS B 1 11  ? 153.111 102.089 68.398  1.00 141.34 ? 11  CYS E CB  1 
ATOM 523  S SG  . CYS B 1 11  ? 151.662 102.710 69.281  1.00 141.34 ? 11  CYS E SG  1 
ATOM 524  N N   . LEU B 1 12  ? 156.563 101.501 69.180  1.00 140.93 ? 12  LEU E N   1 
ATOM 525  C CA  . LEU B 1 12  ? 157.761 100.777 68.774  1.00 140.93 ? 12  LEU E CA  1 
ATOM 526  C C   . LEU B 1 12  ? 157.667 99.285  69.068  1.00 140.93 ? 12  LEU E C   1 
ATOM 527  O O   . LEU B 1 12  ? 157.883 98.462  68.174  1.00 140.93 ? 12  LEU E O   1 
ATOM 528  C CB  . LEU B 1 12  ? 158.990 101.369 69.475  1.00 140.93 ? 12  LEU E CB  1 
ATOM 529  C CG  . LEU B 1 12  ? 159.272 102.848 69.195  1.00 140.93 ? 12  LEU E CG  1 
ATOM 530  C CD1 . LEU B 1 12  ? 160.524 103.298 69.932  1.00 140.93 ? 12  LEU E CD1 1 
ATOM 531  C CD2 . LEU B 1 12  ? 159.403 103.111 67.701  1.00 140.93 ? 12  LEU E CD2 1 
ATOM 532  N N   . GLN B 1 13  ? 157.349 98.920  70.308  1.00 137.51 ? 13  GLN E N   1 
ATOM 533  C CA  . GLN B 1 13  ? 157.210 97.525  70.728  1.00 137.51 ? 13  GLN E CA  1 
ATOM 534  C C   . GLN B 1 13  ? 155.769 97.323  71.187  1.00 137.51 ? 13  GLN E C   1 
ATOM 535  O O   . GLN B 1 13  ? 155.447 97.485  72.365  1.00 137.51 ? 13  GLN E O   1 
ATOM 536  C CB  . GLN B 1 13  ? 158.215 97.182  71.834  1.00 137.51 ? 13  GLN E CB  1 
ATOM 537  C CG  . GLN B 1 13  ? 158.081 95.763  72.376  1.00 137.51 ? 13  GLN E CG  1 
ATOM 538  C CD  . GLN B 1 13  ? 157.401 95.702  73.734  1.00 137.51 ? 13  GLN E CD  1 
ATOM 539  O OE1 . GLN B 1 13  ? 157.075 96.729  74.330  1.00 137.51 ? 13  GLN E OE1 1 
ATOM 540  N NE2 . GLN B 1 13  ? 157.185 94.489  74.230  1.00 137.51 ? 13  GLN E NE2 1 
ATOM 541  N N   . THR B 1 14  ? 154.901 96.969  70.242  1.00 130.68 ? 14  THR E N   1 
ATOM 542  C CA  . THR B 1 14  ? 153.493 96.776  70.558  1.00 130.68 ? 14  THR E CA  1 
ATOM 543  C C   . THR B 1 14  ? 153.317 95.613  71.527  1.00 130.68 ? 14  THR E C   1 
ATOM 544  O O   . THR B 1 14  ? 153.977 94.578  71.410  1.00 130.68 ? 14  THR E O   1 
ATOM 545  C CB  . THR B 1 14  ? 152.693 96.518  69.281  1.00 130.68 ? 14  THR E CB  1 
ATOM 546  O OG1 . THR B 1 14  ? 153.234 95.383  68.593  1.00 130.68 ? 14  THR E OG1 1 
ATOM 547  C CG2 . THR B 1 14  ? 152.742 97.732  68.366  1.00 130.68 ? 14  THR E CG2 1 
ATOM 548  N N   . LEU B 1 15  ? 152.416 95.792  72.489  1.00 130.23 ? 15  LEU E N   1 
ATOM 549  C CA  . LEU B 1 15  ? 152.141 94.748  73.461  1.00 130.23 ? 15  LEU E CA  1 
ATOM 550  C C   . LEU B 1 15  ? 151.381 93.597  72.803  1.00 130.23 ? 15  LEU E C   1 
ATOM 551  O O   . LEU B 1 15  ? 150.853 93.713  71.694  1.00 130.23 ? 15  LEU E O   1 
ATOM 552  C CB  . LEU B 1 15  ? 151.340 95.308  74.636  1.00 130.23 ? 15  LEU E CB  1 
ATOM 553  C CG  . LEU B 1 15  ? 151.865 96.598  75.273  1.00 130.23 ? 15  LEU E CG  1 
ATOM 554  C CD1 . LEU B 1 15  ? 151.268 96.779  76.659  1.00 130.23 ? 15  LEU E CD1 1 
ATOM 555  C CD2 . LEU B 1 15  ? 153.385 96.601  75.341  1.00 130.23 ? 15  LEU E CD2 1 
ATOM 556  N N   . GLN B 1 16  ? 151.332 92.467  73.511  1.00 121.90 ? 16  GLN E N   1 
ATOM 557  C CA  . GLN B 1 16  ? 150.640 91.273  73.036  1.00 121.90 ? 16  GLN E CA  1 
ATOM 558  C C   . GLN B 1 16  ? 149.448 90.914  73.917  1.00 121.90 ? 16  GLN E C   1 
ATOM 559  O O   . GLN B 1 16  ? 148.812 89.878  73.700  1.00 121.90 ? 16  GLN E O   1 
ATOM 560  C CB  . GLN B 1 16  ? 151.610 90.092  72.957  1.00 121.90 ? 16  GLN E CB  1 
ATOM 561  C CG  . GLN B 1 16  ? 152.863 90.372  72.143  1.00 121.90 ? 16  GLN E CG  1 
ATOM 562  C CD  . GLN B 1 16  ? 152.555 90.753  70.709  1.00 121.90 ? 16  GLN E CD  1 
ATOM 563  O OE1 . GLN B 1 16  ? 151.946 89.982  69.967  1.00 121.90 ? 16  GLN E OE1 1 
ATOM 564  N NE2 . GLN B 1 16  ? 152.974 91.949  70.311  1.00 121.90 ? 16  GLN E NE2 1 
ATOM 565  N N   . GLY B 1 17  ? 149.129 91.746  74.905  1.00 121.77 ? 17  GLY E N   1 
ATOM 566  C CA  . GLY B 1 17  ? 147.983 91.490  75.755  1.00 121.77 ? 17  GLY E CA  1 
ATOM 567  C C   . GLY B 1 17  ? 147.639 92.648  76.668  1.00 121.77 ? 17  GLY E C   1 
ATOM 568  O O   . GLY B 1 17  ? 148.508 93.182  77.363  1.00 121.77 ? 17  GLY E O   1 
ATOM 569  N N   . ILE B 1 18  ? 146.367 93.039  76.676  1.00 115.33 ? 18  ILE E N   1 
ATOM 570  C CA  . ILE B 1 18  ? 145.858 94.088  77.549  1.00 115.33 ? 18  ILE E CA  1 
ATOM 571  C C   . ILE B 1 18  ? 144.471 93.679  78.020  1.00 115.33 ? 18  ILE E C   1 
ATOM 572  O O   . ILE B 1 18  ? 143.675 93.141  77.242  1.00 115.33 ? 18  ILE E O   1 
ATOM 573  C CB  . ILE B 1 18  ? 145.818 95.458  76.838  1.00 115.33 ? 18  ILE E CB  1 
ATOM 574  C CG1 . ILE B 1 18  ? 147.211 95.808  76.308  1.00 115.33 ? 18  ILE E CG1 1 
ATOM 575  C CG2 . ILE B 1 18  ? 145.309 96.544  77.788  1.00 115.33 ? 18  ILE E CG2 1 
ATOM 576  C CD1 . ILE B 1 18  ? 147.437 97.284  76.057  1.00 115.33 ? 18  ILE E CD1 1 
ATOM 577  N N   . HIS B 1 19  ? 144.185 93.933  79.291  1.00 116.74 ? 19  HIS E N   1 
ATOM 578  C CA  . HIS B 1 19  ? 142.902 93.534  79.845  1.00 116.74 ? 19  HIS E CA  1 
ATOM 579  C C   . HIS B 1 19  ? 141.785 94.342  79.186  1.00 116.74 ? 19  HIS E C   1 
ATOM 580  O O   . HIS B 1 19  ? 141.796 95.577  79.246  1.00 116.74 ? 19  HIS E O   1 
ATOM 581  C CB  . HIS B 1 19  ? 142.888 93.745  81.359  1.00 116.74 ? 19  HIS E CB  1 
ATOM 582  C CG  . HIS B 1 19  ? 141.750 93.064  82.053  1.00 116.74 ? 19  HIS E CG  1 
ATOM 583  N ND1 . HIS B 1 19  ? 141.543 91.703  81.982  1.00 116.74 ? 19  HIS E ND1 1 
ATOM 584  C CD2 . HIS B 1 19  ? 140.762 93.554  82.837  1.00 116.74 ? 19  HIS E CD2 1 
ATOM 585  C CE1 . HIS B 1 19  ? 140.474 91.385  82.689  1.00 116.74 ? 19  HIS E CE1 1 
ATOM 586  N NE2 . HIS B 1 19  ? 139.981 92.490  83.218  1.00 116.74 ? 19  HIS E NE2 1 
ATOM 587  N N   . PRO B 1 20  ? 140.807 93.687  78.548  1.00 106.22 ? 20  PRO E N   1 
ATOM 588  C CA  . PRO B 1 20  ? 139.772 94.458  77.836  1.00 106.22 ? 20  PRO E CA  1 
ATOM 589  C C   . PRO B 1 20  ? 139.015 95.431  78.722  1.00 106.22 ? 20  PRO E C   1 
ATOM 590  O O   . PRO B 1 20  ? 138.650 96.522  78.266  1.00 106.22 ? 20  PRO E O   1 
ATOM 591  C CB  . PRO B 1 20  ? 138.848 93.365  77.279  1.00 106.22 ? 20  PRO E CB  1 
ATOM 592  C CG  . PRO B 1 20  ? 139.695 92.150  77.203  1.00 106.22 ? 20  PRO E CG  1 
ATOM 593  C CD  . PRO B 1 20  ? 140.626 92.236  78.369  1.00 106.22 ? 20  PRO E CD  1 
ATOM 594  N N   . LYS B 1 21  ? 138.767 95.069  79.981  1.00 118.37 ? 21  LYS E N   1 
ATOM 595  C CA  . LYS B 1 21  ? 137.941 95.912  80.840  1.00 118.37 ? 21  LYS E CA  1 
ATOM 596  C C   . LYS B 1 21  ? 138.659 97.204  81.211  1.00 118.37 ? 21  LYS E C   1 
ATOM 597  O O   . LYS B 1 21  ? 138.013 98.229  81.458  1.00 118.37 ? 21  LYS E O   1 
ATOM 598  C CB  . LYS B 1 21  ? 137.536 95.152  82.094  1.00 30.00  ? 21  LYS E CB  1 
ATOM 599  N N   . ASN B 1 22  ? 139.988 97.179  81.256  1.00 108.97 ? 22  ASN E N   1 
ATOM 600  C CA  . ASN B 1 22  ? 140.764 98.323  81.717  1.00 108.97 ? 22  ASN E CA  1 
ATOM 601  C C   . ASN B 1 22  ? 140.988 99.376  80.637  1.00 108.97 ? 22  ASN E C   1 
ATOM 602  O O   . ASN B 1 22  ? 141.457 100.472 80.958  1.00 108.97 ? 22  ASN E O   1 
ATOM 603  C CB  . ASN B 1 22  ? 142.115 97.850  82.257  1.00 108.97 ? 22  ASN E CB  1 
ATOM 604  C CG  . ASN B 1 22  ? 142.007 97.234  83.636  1.00 108.97 ? 22  ASN E CG  1 
ATOM 605  O OD1 . ASN B 1 22  ? 141.079 97.526  84.390  1.00 108.97 ? 22  ASN E OD1 1 
ATOM 606  N ND2 . ASN B 1 22  ? 142.957 96.371  83.974  1.00 108.97 ? 22  ASN E ND2 1 
ATOM 607  N N   . ILE B 1 23  ? 140.668 99.083  79.381  1.00 88.01  ? 23  ILE E N   1 
ATOM 608  C CA  . ILE B 1 23  ? 140.885 100.023 78.288  1.00 88.01  ? 23  ILE E CA  1 
ATOM 609  C C   . ILE B 1 23  ? 139.740 101.026 78.265  1.00 88.01  ? 23  ILE E C   1 
ATOM 610  O O   . ILE B 1 23  ? 138.565 100.644 78.238  1.00 88.01  ? 23  ILE E O   1 
ATOM 611  C CB  . ILE B 1 23  ? 141.004 99.287  76.943  1.00 88.01  ? 23  ILE E CB  1 
ATOM 612  C CG1 . ILE B 1 23  ? 142.400 98.675  76.805  1.00 88.01  ? 23  ILE E CG1 1 
ATOM 613  C CG2 . ILE B 1 23  ? 140.716 100.237 75.787  1.00 88.01  ? 23  ILE E CG2 1 
ATOM 614  C CD1 . ILE B 1 23  ? 142.565 97.772  75.601  1.00 88.01  ? 23  ILE E CD1 1 
ATOM 615  N N   . GLN B 1 24  ? 140.085 102.313 78.276  1.00 81.41  ? 24  GLN E N   1 
ATOM 616  C CA  . GLN B 1 24  ? 139.100 103.385 78.225  1.00 81.41  ? 24  GLN E CA  1 
ATOM 617  C C   . GLN B 1 24  ? 138.798 103.853 76.811  1.00 81.41  ? 24  GLN E C   1 
ATOM 618  O O   . GLN B 1 24  ? 137.628 104.076 76.482  1.00 81.41  ? 24  GLN E O   1 
ATOM 619  C CB  . GLN B 1 24  ? 139.580 104.585 79.048  1.00 81.41  ? 24  GLN E CB  1 
ATOM 620  C CG  . GLN B 1 24  ? 138.484 105.263 79.848  1.00 81.41  ? 24  GLN E CG  1 
ATOM 621  C CD  . GLN B 1 24  ? 138.932 106.581 80.448  1.00 81.41  ? 24  GLN E CD  1 
ATOM 622  O OE1 . GLN B 1 24  ? 139.852 107.225 79.943  1.00 81.41  ? 24  GLN E OE1 1 
ATOM 623  N NE2 . GLN B 1 24  ? 138.282 106.989 81.530  1.00 81.41  ? 24  GLN E NE2 1 
ATOM 624  N N   . SER B 1 25  ? 139.817 104.007 75.970  1.00 80.00  ? 25  SER E N   1 
ATOM 625  C CA  . SER B 1 25  ? 139.616 104.453 74.600  1.00 80.00  ? 25  SER E CA  1 
ATOM 626  C C   . SER B 1 25  ? 140.799 103.998 73.761  1.00 80.00  ? 25  SER E C   1 
ATOM 627  O O   . SER B 1 25  ? 141.925 103.902 74.253  1.00 80.00  ? 25  SER E O   1 
ATOM 628  C CB  . SER B 1 25  ? 139.462 105.974 74.522  1.00 80.00  ? 25  SER E CB  1 
ATOM 629  O OG  . SER B 1 25  ? 140.672 106.627 74.864  1.00 80.00  ? 25  SER E OG  1 
ATOM 630  N N   . VAL B 1 26  ? 140.526 103.720 72.490  1.00 82.50  ? 26  VAL E N   1 
ATOM 631  C CA  . VAL B 1 26  ? 141.538 103.275 71.541  1.00 82.50  ? 26  VAL E CA  1 
ATOM 632  C C   . VAL B 1 26  ? 141.611 104.286 70.408  1.00 82.50  ? 26  VAL E C   1 
ATOM 633  O O   . VAL B 1 26  ? 140.585 104.650 69.822  1.00 82.50  ? 26  VAL E O   1 
ATOM 634  C CB  . VAL B 1 26  ? 141.227 101.866 70.995  1.00 82.50  ? 26  VAL E CB  1 
ATOM 635  C CG1 . VAL B 1 26  ? 142.194 101.501 69.881  1.00 82.50  ? 26  VAL E CG1 1 
ATOM 636  C CG2 . VAL B 1 26  ? 141.287 100.842 72.115  1.00 82.50  ? 26  VAL E CG2 1 
ATOM 637  N N   . ASN B 1 27  ? 142.824 104.738 70.101  1.00 90.73  ? 27  ASN E N   1 
ATOM 638  C CA  . ASN B 1 27  ? 143.067 105.713 69.045  1.00 90.73  ? 27  ASN E CA  1 
ATOM 639  C C   . ASN B 1 27  ? 143.827 105.028 67.920  1.00 90.73  ? 27  ASN E C   1 
ATOM 640  O O   . ASN B 1 27  ? 144.876 104.421 68.157  1.00 90.73  ? 27  ASN E O   1 
ATOM 641  C CB  . ASN B 1 27  ? 143.854 106.911 69.578  1.00 90.73  ? 27  ASN E CB  1 
ATOM 642  C CG  . ASN B 1 27  ? 144.185 107.916 68.495  1.00 90.73  ? 27  ASN E CG  1 
ATOM 643  O OD1 . ASN B 1 27  ? 143.378 108.171 67.602  1.00 90.73  ? 27  ASN E OD1 1 
ATOM 644  N ND2 . ASN B 1 27  ? 145.377 108.495 68.569  1.00 90.73  ? 27  ASN E ND2 1 
ATOM 645  N N   . VAL B 1 28  ? 143.298 105.124 66.705  1.00 84.32  ? 28  VAL E N   1 
ATOM 646  C CA  . VAL B 1 28  ? 143.895 104.499 65.530  1.00 84.32  ? 28  VAL E CA  1 
ATOM 647  C C   . VAL B 1 28  ? 144.417 105.601 64.621  1.00 84.32  ? 28  VAL E C   1 
ATOM 648  O O   . VAL B 1 28  ? 143.647 106.450 64.157  1.00 84.32  ? 28  VAL E O   1 
ATOM 649  C CB  . VAL B 1 28  ? 142.881 103.612 64.793  1.00 84.32  ? 28  VAL E CB  1 
ATOM 650  C CG1 . VAL B 1 28  ? 143.558 102.860 63.660  1.00 84.32  ? 28  VAL E CG1 1 
ATOM 651  C CG2 . VAL B 1 28  ? 142.221 102.646 65.761  1.00 84.32  ? 28  VAL E CG2 1 
ATOM 652  N N   . LYS B 1 29  ? 145.714 105.562 64.345  1.00 101.73 ? 29  LYS E N   1 
ATOM 653  C CA  . LYS B 1 29  ? 146.339 106.607 63.506  1.00 101.73 ? 29  LYS E CA  1 
ATOM 654  C C   . LYS B 1 29  ? 146.833 105.956 62.230  1.00 101.73 ? 29  LYS E C   1 
ATOM 655  O O   . LYS B 1 29  ? 147.709 105.094 62.309  1.00 101.73 ? 29  LYS E O   1 
ATOM 656  C CB  . LYS B 1 29  ? 147.491 107.280 64.245  1.00 30.00  ? 29  LYS E CB  1 
ATOM 657  N N   . SER B 1 30  ? 146.294 106.383 61.108  1.00 113.27 ? 30  SER E N   1 
ATOM 658  C CA  . SER B 1 30  ? 146.643 105.722 59.840  1.00 113.27 ? 30  SER E CA  1 
ATOM 659  C C   . SER B 1 30  ? 147.971 106.251 59.339  1.00 113.27 ? 30  SER E C   1 
ATOM 660  O O   . SER B 1 30  ? 148.468 107.246 59.885  1.00 113.27 ? 30  SER E O   1 
ATOM 661  C CB  . SER B 1 30  ? 145.596 105.978 58.832  1.00 113.27 ? 30  SER E CB  1 
ATOM 662  O OG  . SER B 1 30  ? 146.002 107.026 57.966  1.00 113.27 ? 30  SER E OG  1 
ATOM 663  N N   . PRO B 1 31  ? 148.539 105.624 58.296  1.00 121.75 ? 31  PRO E N   1 
ATOM 664  C CA  . PRO B 1 31  ? 149.862 106.024 57.805  1.00 121.75 ? 31  PRO E CA  1 
ATOM 665  C C   . PRO B 1 31  ? 149.884 107.490 57.402  1.00 121.75 ? 31  PRO E C   1 
ATOM 666  O O   . PRO B 1 31  ? 148.923 108.013 56.834  1.00 121.75 ? 31  PRO E O   1 
ATOM 667  C CB  . PRO B 1 31  ? 150.083 105.103 56.600  1.00 121.75 ? 31  PRO E CB  1 
ATOM 668  C CG  . PRO B 1 31  ? 149.230 103.913 56.885  1.00 121.75 ? 31  PRO E CG  1 
ATOM 669  C CD  . PRO B 1 31  ? 148.007 104.473 57.547  1.00 121.75 ? 31  PRO E CD  1 
ATOM 670  N N   . GLY B 1 32  ? 150.997 108.153 57.703  1.00 140.74 ? 32  GLY E N   1 
ATOM 671  C CA  . GLY B 1 32  ? 151.146 109.559 57.418  1.00 140.74 ? 32  GLY E CA  1 
ATOM 672  C C   . GLY B 1 32  ? 152.599 109.985 57.367  1.00 140.74 ? 32  GLY E C   1 
ATOM 673  O O   . GLY B 1 32  ? 153.516 109.167 57.496  1.00 140.74 ? 32  GLY E O   1 
ATOM 674  N N   . PRO B 1 33  ? 152.837 111.284 57.174  1.00 150.98 ? 33  PRO E N   1 
ATOM 675  C CA  . PRO B 1 33  ? 154.225 111.768 57.096  1.00 150.98 ? 33  PRO E CA  1 
ATOM 676  C C   . PRO B 1 33  ? 155.031 111.511 58.355  1.00 150.98 ? 33  PRO E C   1 
ATOM 677  O O   . PRO B 1 33  ? 156.260 111.388 58.268  1.00 150.98 ? 33  PRO E O   1 
ATOM 678  C CB  . PRO B 1 33  ? 154.060 113.272 56.833  1.00 150.98 ? 33  PRO E CB  1 
ATOM 679  C CG  . PRO B 1 33  ? 152.680 113.601 57.297  1.00 150.98 ? 33  PRO E CG  1 
ATOM 680  C CD  . PRO B 1 33  ? 151.858 112.376 57.049  1.00 150.98 ? 33  PRO E CD  1 
ATOM 681  N N   . HIS B 1 34  ? 154.389 111.423 59.517  1.00 155.04 ? 34  HIS E N   1 
ATOM 682  C CA  . HIS B 1 34  ? 155.087 111.241 60.783  1.00 155.04 ? 34  HIS E CA  1 
ATOM 683  C C   . HIS B 1 34  ? 155.352 109.779 61.117  1.00 155.04 ? 34  HIS E C   1 
ATOM 684  O O   . HIS B 1 34  ? 156.074 109.500 62.079  1.00 155.04 ? 34  HIS E O   1 
ATOM 685  C CB  . HIS B 1 34  ? 154.287 111.886 61.919  1.00 155.04 ? 34  HIS E CB  1 
ATOM 686  C CG  . HIS B 1 34  ? 154.158 113.373 61.799  1.00 155.04 ? 34  HIS E CG  1 
ATOM 687  N ND1 . HIS B 1 34  ? 155.249 114.209 61.704  1.00 155.04 ? 34  HIS E ND1 1 
ATOM 688  C CD2 . HIS B 1 34  ? 153.066 114.173 61.761  1.00 155.04 ? 34  HIS E CD2 1 
ATOM 689  C CE1 . HIS B 1 34  ? 154.835 115.461 61.611  1.00 155.04 ? 34  HIS E CE1 1 
ATOM 690  N NE2 . HIS B 1 34  ? 153.515 115.466 61.644  1.00 155.04 ? 34  HIS E NE2 1 
ATOM 691  N N   . CYS B 1 35  ? 154.792 108.840 60.354  1.00 146.22 ? 35  CYS E N   1 
ATOM 692  C CA  . CYS B 1 35  ? 155.025 107.424 60.606  1.00 146.22 ? 35  CYS E CA  1 
ATOM 693  C C   . CYS B 1 35  ? 154.567 106.586 59.419  1.00 146.22 ? 35  CYS E C   1 
ATOM 694  O O   . CYS B 1 35  ? 153.469 106.792 58.892  1.00 146.22 ? 35  CYS E O   1 
ATOM 695  C CB  . CYS B 1 35  ? 154.304 106.982 61.881  1.00 146.22 ? 35  CYS E CB  1 
ATOM 696  S SG  . CYS B 1 35  ? 154.394 105.206 62.206  1.00 146.22 ? 35  CYS E SG  1 
ATOM 697  N N   . ALA B 1 36  ? 155.403 105.640 58.992  1.00 136.67 ? 36  ALA E N   1 
ATOM 698  C CA  . ALA B 1 36  ? 155.096 104.817 57.830  1.00 136.67 ? 36  ALA E CA  1 
ATOM 699  C C   . ALA B 1 36  ? 154.290 103.570 58.171  1.00 136.67 ? 36  ALA E C   1 
ATOM 700  O O   . ALA B 1 36  ? 153.922 102.826 57.255  1.00 136.67 ? 36  ALA E O   1 
ATOM 701  C CB  . ALA B 1 36  ? 156.391 104.407 57.125  1.00 136.67 ? 36  ALA E CB  1 
ATOM 702  N N   . GLN B 1 37  ? 154.012 103.320 59.446  1.00 136.12 ? 37  GLN E N   1 
ATOM 703  C CA  . GLN B 1 37  ? 153.278 102.141 59.877  1.00 136.12 ? 37  GLN E CA  1 
ATOM 704  C C   . GLN B 1 37  ? 152.033 102.546 60.656  1.00 136.12 ? 37  GLN E C   1 
ATOM 705  O O   . GLN B 1 37  ? 152.001 103.579 61.331  1.00 136.12 ? 37  GLN E O   1 
ATOM 706  C CB  . GLN B 1 37  ? 154.166 101.234 60.716  1.00 30.00  ? 37  GLN E CB  1 
ATOM 707  N N   . THR B 1 38  ? 151.001 101.713 60.554  1.00 114.87 ? 38  THR E N   1 
ATOM 708  C CA  . THR B 1 38  ? 149.761 101.949 61.278  1.00 114.87 ? 38  THR E CA  1 
ATOM 709  C C   . THR B 1 38  ? 149.977 101.741 62.771  1.00 114.87 ? 38  THR E C   1 
ATOM 710  O O   . THR B 1 38  ? 150.627 100.780 63.191  1.00 114.87 ? 38  THR E O   1 
ATOM 711  C CB  . THR B 1 38  ? 148.660 101.014 60.775  1.00 114.87 ? 38  THR E CB  1 
ATOM 712  O OG1 . THR B 1 38  ? 148.413 101.265 59.386  1.00 114.87 ? 38  THR E OG1 1 
ATOM 713  C CG2 . THR B 1 38  ? 147.375 101.223 61.565  1.00 114.87 ? 38  THR E CG2 1 
ATOM 714  N N   . GLU B 1 39  ? 149.428 102.651 63.571  1.00 118.94 ? 39  GLU E N   1 
ATOM 715  C CA  . GLU B 1 39  ? 149.597 102.639 65.017  1.00 118.94 ? 39  GLU E CA  1 
ATOM 716  C C   . GLU B 1 39  ? 148.238 102.570 65.694  1.00 118.94 ? 39  GLU E C   1 
ATOM 717  O O   . GLU B 1 39  ? 147.303 103.271 65.292  1.00 118.94 ? 39  GLU E O   1 
ATOM 718  C CB  . GLU B 1 39  ? 150.371 103.864 65.480  1.00 30.00  ? 39  GLU E CB  1 
ATOM 719  N N   . VAL B 1 40  ? 148.134 101.728 66.717  1.00 95.43  ? 40  VAL E N   1 
ATOM 720  C CA  . VAL B 1 40  ? 146.956 101.652 67.571  1.00 95.43  ? 40  VAL E CA  1 
ATOM 721  C C   . VAL B 1 40  ? 147.420 101.933 68.993  1.00 95.43  ? 40  VAL E C   1 
ATOM 722  O O   . VAL B 1 40  ? 148.304 101.242 69.515  1.00 95.43  ? 40  VAL E O   1 
ATOM 723  C CB  . VAL B 1 40  ? 146.260 100.288 67.470  1.00 95.43  ? 40  VAL E CB  1 
ATOM 724  C CG1 . VAL B 1 40  ? 145.031 100.251 68.366  1.00 95.43  ? 40  VAL E CG1 1 
ATOM 725  C CG2 . VAL B 1 40  ? 145.884 99.991  66.027  1.00 95.43  ? 40  VAL E CG2 1 
ATOM 726  N N   . ILE B 1 41  ? 146.830 102.946 69.621  1.00 96.13  ? 41  ILE E N   1 
ATOM 727  C CA  . ILE B 1 41  ? 147.185 103.360 70.974  1.00 96.13  ? 41  ILE E CA  1 
ATOM 728  C C   . ILE B 1 41  ? 145.932 103.275 71.832  1.00 96.13  ? 41  ILE E C   1 
ATOM 729  O O   . ILE B 1 41  ? 144.878 103.805 71.458  1.00 96.13  ? 41  ILE E O   1 
ATOM 730  C CB  . ILE B 1 41  ? 147.777 104.778 70.998  1.00 96.13  ? 41  ILE E CB  1 
ATOM 731  C CG1 . ILE B 1 41  ? 149.006 104.863 70.091  1.00 96.13  ? 41  ILE E CG1 1 
ATOM 732  C CG2 . ILE B 1 41  ? 148.145 105.174 72.420  1.00 96.13  ? 41  ILE E CG2 1 
ATOM 733  C CD1 . ILE B 1 41  ? 149.364 106.275 69.681  1.00 96.13  ? 41  ILE E CD1 1 
ATOM 734  N N   . ALA B 1 42  ? 146.045 102.610 72.977  1.00 92.63  ? 42  ALA E N   1 
ATOM 735  C CA  . ALA B 1 42  ? 144.940 102.446 73.908  1.00 92.63  ? 42  ALA E CA  1 
ATOM 736  C C   . ALA B 1 42  ? 145.274 103.128 75.227  1.00 92.63  ? 42  ALA E C   1 
ATOM 737  O O   . ALA B 1 42  ? 146.351 102.914 75.792  1.00 92.63  ? 42  ALA E O   1 
ATOM 738  C CB  . ALA B 1 42  ? 144.639 100.966 74.148  1.00 92.63  ? 42  ALA E CB  1 
ATOM 739  N N   . THR B 1 43  ? 144.346 103.946 75.713  1.00 83.11  ? 43  THR E N   1 
ATOM 740  C CA  . THR B 1 43  ? 144.515 104.675 76.963  1.00 83.11  ? 43  THR E CA  1 
ATOM 741  C C   . THR B 1 43  ? 143.783 103.931 78.071  1.00 83.11  ? 43  THR E C   1 
ATOM 742  O O   . THR B 1 43  ? 142.549 103.860 78.067  1.00 83.11  ? 43  THR E O   1 
ATOM 743  C CB  . THR B 1 43  ? 143.989 106.105 76.836  1.00 83.11  ? 43  THR E CB  1 
ATOM 744  O OG1 . THR B 1 43  ? 144.762 106.817 75.862  1.00 83.11  ? 43  THR E OG1 1 
ATOM 745  C CG2 . THR B 1 43  ? 144.069 106.829 78.172  1.00 83.11  ? 43  THR E CG2 1 
ATOM 746  N N   . LEU B 1 44  ? 144.540 103.381 79.013  1.00 93.87  ? 44  LEU E N   1 
ATOM 747  C CA  . LEU B 1 44  ? 143.971 102.637 80.124  1.00 93.87  ? 44  LEU E CA  1 
ATOM 748  C C   . LEU B 1 44  ? 143.296 103.583 81.110  1.00 93.87  ? 44  LEU E C   1 
ATOM 749  O O   . LEU B 1 44  ? 143.560 104.787 81.138  1.00 93.87  ? 44  LEU E O   1 
ATOM 750  C CB  . LEU B 1 44  ? 145.052 101.821 80.834  1.00 93.87  ? 44  LEU E CB  1 
ATOM 751  C CG  . LEU B 1 44  ? 145.841 100.850 79.952  1.00 93.87  ? 44  LEU E CG  1 
ATOM 752  C CD1 . LEU B 1 44  ? 146.851 100.080 80.783  1.00 93.87  ? 44  LEU E CD1 1 
ATOM 753  C CD2 . LEU B 1 44  ? 144.907 99.894  79.227  1.00 93.87  ? 44  LEU E CD2 1 
ATOM 754  N N   . LYS B 1 45  ? 142.409 103.016 81.929  1.00 88.37  ? 45  LYS E N   1 
ATOM 755  C CA  . LYS B 1 45  ? 141.655 103.812 82.888  1.00 88.37  ? 45  LYS E CA  1 
ATOM 756  C C   . LYS B 1 45  ? 142.544 104.509 83.907  1.00 88.37  ? 45  LYS E C   1 
ATOM 757  O O   . LYS B 1 45  ? 142.103 105.489 84.517  1.00 88.37  ? 45  LYS E O   1 
ATOM 758  C CB  . LYS B 1 45  ? 140.644 102.927 83.617  1.00 88.37  ? 45  LYS E CB  1 
ATOM 759  C CG  . LYS B 1 45  ? 139.442 102.539 82.776  1.00 88.37  ? 45  LYS E CG  1 
ATOM 760  C CD  . LYS B 1 45  ? 138.439 101.736 83.585  1.00 88.37  ? 45  LYS E CD  1 
ATOM 761  C CE  . LYS B 1 45  ? 137.201 101.412 82.769  1.00 88.37  ? 45  LYS E CE  1 
ATOM 762  N NZ  . LYS B 1 45  ? 136.309 100.448 83.470  1.00 88.37  ? 45  LYS E NZ  1 
ATOM 763  N N   . ASN B 1 46  ? 143.773 104.038 84.106  1.00 93.76  ? 46  ASN E N   1 
ATOM 764  C CA  . ASN B 1 46  ? 144.677 104.605 85.096  1.00 93.76  ? 46  ASN E CA  1 
ATOM 765  C C   . ASN B 1 46  ? 145.576 105.691 84.519  1.00 93.76  ? 46  ASN E C   1 
ATOM 766  O O   . ASN B 1 46  ? 146.460 106.188 85.224  1.00 93.76  ? 46  ASN E O   1 
ATOM 767  C CB  . ASN B 1 46  ? 145.528 103.498 85.723  1.00 93.76  ? 46  ASN E CB  1 
ATOM 768  C CG  . ASN B 1 46  ? 146.425 102.802 84.717  1.00 93.76  ? 46  ASN E CG  1 
ATOM 769  O OD1 . ASN B 1 46  ? 146.650 103.300 83.614  1.00 93.76  ? 46  ASN E OD1 1 
ATOM 770  N ND2 . ASN B 1 46  ? 146.937 101.636 85.093  1.00 93.76  ? 46  ASN E ND2 1 
ATOM 771  N N   . GLY B 1 47  ? 145.373 106.071 83.257  1.00 92.14  ? 47  GLY E N   1 
ATOM 772  C CA  . GLY B 1 47  ? 146.154 107.107 82.623  1.00 92.14  ? 47  GLY E CA  1 
ATOM 773  C C   . GLY B 1 47  ? 147.347 106.615 81.832  1.00 92.14  ? 47  GLY E C   1 
ATOM 774  O O   . GLY B 1 47  ? 147.929 107.394 81.069  1.00 92.14  ? 47  GLY E O   1 
ATOM 775  N N   . ARG B 1 48  ? 147.729 105.351 81.987  1.00 102.73 ? 48  ARG E N   1 
ATOM 776  C CA  . ARG B 1 48  ? 148.837 104.798 81.225  1.00 102.73 ? 48  ARG E CA  1 
ATOM 777  C C   . ARG B 1 48  ? 148.434 104.593 79.771  1.00 102.73 ? 48  ARG E C   1 
ATOM 778  O O   . ARG B 1 48  ? 147.263 104.369 79.453  1.00 102.73 ? 48  ARG E O   1 
ATOM 779  C CB  . ARG B 1 48  ? 149.297 103.471 81.827  1.00 102.73 ? 48  ARG E CB  1 
ATOM 780  C CG  . ARG B 1 48  ? 149.935 103.598 83.201  1.00 102.73 ? 48  ARG E CG  1 
ATOM 781  C CD  . ARG B 1 48  ? 150.206 102.235 83.823  1.00 102.73 ? 48  ARG E CD  1 
ATOM 782  N NE  . ARG B 1 48  ? 150.660 101.255 82.843  1.00 102.73 ? 48  ARG E NE  1 
ATOM 783  C CZ  . ARG B 1 48  ? 150.704 99.947  83.057  1.00 102.73 ? 48  ARG E CZ  1 
ATOM 784  N NH1 . ARG B 1 48  ? 150.330 99.422  84.213  1.00 102.73 ? 48  ARG E NH1 1 
ATOM 785  N NH2 . ARG B 1 48  ? 151.132 99.145  82.087  1.00 102.73 ? 48  ARG E NH2 1 
ATOM 786  N N   . LYS B 1 49  ? 149.423 104.671 78.886  1.00 102.48 ? 49  LYS E N   1 
ATOM 787  C CA  . LYS B 1 49  ? 149.223 104.480 77.458  1.00 102.48 ? 49  LYS E CA  1 
ATOM 788  C C   . LYS B 1 49  ? 149.978 103.241 76.997  1.00 102.48 ? 49  LYS E C   1 
ATOM 789  O O   . LYS B 1 49  ? 151.156 103.062 77.324  1.00 102.48 ? 49  LYS E O   1 
ATOM 790  C CB  . LYS B 1 49  ? 149.692 105.706 76.670  1.00 102.48 ? 49  LYS E CB  1 
ATOM 791  C CG  . LYS B 1 49  ? 148.847 106.947 76.911  1.00 102.48 ? 49  LYS E CG  1 
ATOM 792  C CD  . LYS B 1 49  ? 149.318 108.119 76.067  1.00 102.48 ? 49  LYS E CD  1 
ATOM 793  C CE  . LYS B 1 49  ? 148.332 109.275 76.123  1.00 102.48 ? 49  LYS E CE  1 
ATOM 794  N NZ  . LYS B 1 49  ? 148.817 110.459 75.362  1.00 102.48 ? 49  LYS E NZ  1 
ATOM 795  N N   . ALA B 1 50  ? 149.293 102.387 76.239  1.00 111.19 ? 50  ALA E N   1 
ATOM 796  C CA  . ALA B 1 50  ? 149.869 101.148 75.741  1.00 111.19 ? 50  ALA E CA  1 
ATOM 797  C C   . ALA B 1 50  ? 149.547 101.000 74.263  1.00 111.19 ? 50  ALA E C   1 
ATOM 798  O O   . ALA B 1 50  ? 148.484 101.427 73.806  1.00 111.19 ? 50  ALA E O   1 
ATOM 799  C CB  . ALA B 1 50  ? 149.341 99.935  76.515  1.00 111.19 ? 50  ALA E CB  1 
ATOM 800  N N   . CYS B 1 51  ? 150.471 100.393 73.523  1.00 122.85 ? 51  CYS E N   1 
ATOM 801  C CA  . CYS B 1 51  ? 150.318 100.209 72.086  1.00 122.85 ? 51  CYS E CA  1 
ATOM 802  C C   . CYS B 1 51  ? 149.862 98.785  71.795  1.00 122.85 ? 51  CYS E C   1 
ATOM 803  O O   . CYS B 1 51  ? 150.424 97.825  72.332  1.00 122.85 ? 51  CYS E O   1 
ATOM 804  C CB  . CYS B 1 51  ? 151.635 100.500 71.367  1.00 122.85 ? 51  CYS E CB  1 
ATOM 805  S SG  . CYS B 1 51  ? 152.027 102.260 71.228  1.00 122.85 ? 51  CYS E SG  1 
ATOM 806  N N   . LEU B 1 52  ? 148.848 98.655  70.946  1.00 109.22 ? 52  LEU E N   1 
ATOM 807  C CA  . LEU B 1 52  ? 148.308 97.364  70.548  1.00 109.22 ? 52  LEU E CA  1 
ATOM 808  C C   . LEU B 1 52  ? 148.730 97.038  69.122  1.00 109.22 ? 52  LEU E C   1 
ATOM 809  O O   . LEU B 1 52  ? 148.882 97.929  68.281  1.00 109.22 ? 52  LEU E O   1 
ATOM 810  C CB  . LEU B 1 52  ? 146.780 97.349  70.649  1.00 109.22 ? 52  LEU E CB  1 
ATOM 811  C CG  . LEU B 1 52  ? 146.190 97.559  72.044  1.00 109.22 ? 52  LEU E CG  1 
ATOM 812  C CD1 . LEU B 1 52  ? 144.674 97.613  71.978  1.00 109.22 ? 52  LEU E CD1 1 
ATOM 813  C CD2 . LEU B 1 52  ? 146.644 96.457  72.983  1.00 109.22 ? 52  LEU E CD2 1 
ATOM 814  N N   . ASN B 1 53  ? 148.916 95.751  68.856  1.00 119.08 ? 53  ASN E N   1 
ATOM 815  C CA  . ASN B 1 53  ? 149.317 95.306  67.528  1.00 119.08 ? 53  ASN E CA  1 
ATOM 816  C C   . ASN B 1 53  ? 148.136 95.428  66.571  1.00 119.08 ? 53  ASN E C   1 
ATOM 817  O O   . ASN B 1 53  ? 147.092 94.814  66.815  1.00 119.08 ? 53  ASN E O   1 
ATOM 818  C CB  . ASN B 1 53  ? 149.808 93.865  67.576  1.00 119.08 ? 53  ASN E CB  1 
ATOM 819  C CG  . ASN B 1 53  ? 150.171 93.321  66.206  1.00 119.08 ? 53  ASN E CG  1 
ATOM 820  O OD1 . ASN B 1 53  ? 150.169 94.048  65.213  1.00 119.08 ? 53  ASN E OD1 1 
ATOM 821  N ND2 . ASN B 1 53  ? 150.485 92.032  66.148  1.00 119.08 ? 53  ASN E ND2 1 
ATOM 822  N N   . PRO B 1 54  ? 148.248 96.199  65.485  1.00 113.78 ? 54  PRO E N   1 
ATOM 823  C CA  . PRO B 1 54  ? 147.112 96.311  64.556  1.00 113.78 ? 54  PRO E CA  1 
ATOM 824  C C   . PRO B 1 54  ? 146.736 94.999  63.891  1.00 113.78 ? 54  PRO E C   1 
ATOM 825  O O   . PRO B 1 54  ? 145.574 94.832  63.502  1.00 113.78 ? 54  PRO E O   1 
ATOM 826  C CB  . PRO B 1 54  ? 147.599 97.341  63.527  1.00 113.78 ? 54  PRO E CB  1 
ATOM 827  C CG  . PRO B 1 54  ? 149.083 97.286  63.603  1.00 113.78 ? 54  PRO E CG  1 
ATOM 828  C CD  . PRO B 1 54  ? 149.406 96.990  65.034  1.00 113.78 ? 54  PRO E CD  1 
ATOM 829  N N   . ALA B 1 55  ? 147.675 94.066  63.747  1.00 117.95 ? 55  ALA E N   1 
ATOM 830  C CA  . ALA B 1 55  ? 147.417 92.809  63.058  1.00 117.95 ? 55  ALA E CA  1 
ATOM 831  C C   . ALA B 1 55  ? 146.851 91.728  63.968  1.00 117.95 ? 55  ALA E C   1 
ATOM 832  O O   . ALA B 1 55  ? 146.452 90.670  63.470  1.00 117.95 ? 55  ALA E O   1 
ATOM 833  C CB  . ALA B 1 55  ? 148.705 92.295  62.406  1.00 117.95 ? 55  ALA E CB  1 
ATOM 834  N N   . SER B 1 56  ? 146.805 91.959  65.274  1.00 119.80 ? 56  SER E N   1 
ATOM 835  C CA  . SER B 1 56  ? 146.317 90.945  66.201  1.00 119.80 ? 56  SER E CA  1 
ATOM 836  C C   . SER B 1 56  ? 144.808 90.788  66.054  1.00 119.80 ? 56  SER E C   1 
ATOM 837  O O   . SER B 1 56  ? 144.080 91.779  66.181  1.00 119.80 ? 56  SER E O   1 
ATOM 838  C CB  . SER B 1 56  ? 146.664 91.324  67.634  1.00 119.80 ? 56  SER E CB  1 
ATOM 839  O OG  . SER B 1 56  ? 146.020 90.464  68.557  1.00 119.80 ? 56  SER E OG  1 
ATOM 840  N N   . PRO B 1 57  ? 144.297 89.583  65.788  1.00 109.64 ? 57  PRO E N   1 
ATOM 841  C CA  . PRO B 1 57  ? 142.836 89.412  65.737  1.00 109.64 ? 57  PRO E CA  1 
ATOM 842  C C   . PRO B 1 57  ? 142.139 89.807  67.025  1.00 109.64 ? 57  PRO E C   1 
ATOM 843  O O   . PRO B 1 57  ? 141.007 90.306  66.983  1.00 109.64 ? 57  PRO E O   1 
ATOM 844  C CB  . PRO B 1 57  ? 142.669 87.915  65.441  1.00 109.64 ? 57  PRO E CB  1 
ATOM 845  C CG  . PRO B 1 57  ? 143.938 87.512  64.784  1.00 109.64 ? 57  PRO E CG  1 
ATOM 846  C CD  . PRO B 1 57  ? 145.008 88.349  65.413  1.00 109.64 ? 57  PRO E CD  1 
ATOM 847  N N   . ILE B 1 58  ? 142.782 89.596  68.176  1.00 118.74 ? 58  ILE E N   1 
ATOM 848  C CA  . ILE B 1 58  ? 142.165 89.966  69.445  1.00 118.74 ? 58  ILE E CA  1 
ATOM 849  C C   . ILE B 1 58  ? 141.954 91.472  69.519  1.00 118.74 ? 58  ILE E C   1 
ATOM 850  O O   . ILE B 1 58  ? 140.929 91.937  70.032  1.00 118.74 ? 58  ILE E O   1 
ATOM 851  C CB  . ILE B 1 58  ? 143.013 89.462  70.627  1.00 118.74 ? 58  ILE E CB  1 
ATOM 852  C CG1 . ILE B 1 58  ? 143.237 87.949  70.529  1.00 118.74 ? 58  ILE E CG1 1 
ATOM 853  C CG2 . ILE B 1 58  ? 142.342 89.812  71.948  1.00 118.74 ? 58  ILE E CG2 1 
ATOM 854  C CD1 . ILE B 1 58  ? 144.411 87.455  71.345  1.00 118.74 ? 58  ILE E CD1 1 
ATOM 855  N N   . VAL B 1 59  ? 142.908 92.257  69.015  1.00 114.32 ? 59  VAL E N   1 
ATOM 856  C CA  . VAL B 1 59  ? 142.760 93.708  69.040  1.00 114.32 ? 59  VAL E CA  1 
ATOM 857  C C   . VAL B 1 59  ? 141.532 94.130  68.245  1.00 114.32 ? 59  VAL E C   1 
ATOM 858  O O   . VAL B 1 59  ? 140.770 95.004  68.674  1.00 114.32 ? 59  VAL E O   1 
ATOM 859  C CB  . VAL B 1 59  ? 144.038 94.380  68.510  1.00 114.32 ? 59  VAL E CB  1 
ATOM 860  C CG1 . VAL B 1 59  ? 143.815 95.872  68.323  1.00 114.32 ? 59  VAL E CG1 1 
ATOM 861  C CG2 . VAL B 1 59  ? 145.198 94.127  69.459  1.00 114.32 ? 59  VAL E CG2 1 
ATOM 862  N N   . LYS B 1 60  ? 141.321 93.523  67.075  1.00 110.98 ? 60  LYS E N   1 
ATOM 863  C CA  . LYS B 1 60  ? 140.126 93.826  66.295  1.00 110.98 ? 60  LYS E CA  1 
ATOM 864  C C   . LYS B 1 60  ? 138.863 93.551  67.100  1.00 110.98 ? 60  LYS E C   1 
ATOM 865  O O   . LYS B 1 60  ? 137.875 94.287  66.991  1.00 110.98 ? 60  LYS E O   1 
ATOM 866  C CB  . LYS B 1 60  ? 140.123 93.011  65.002  1.00 110.98 ? 60  LYS E CB  1 
ATOM 867  C CG  . LYS B 1 60  ? 140.628 93.771  63.787  1.00 110.98 ? 60  LYS E CG  1 
ATOM 868  C CD  . LYS B 1 60  ? 140.559 92.918  62.531  1.00 110.98 ? 60  LYS E CD  1 
ATOM 869  C CE  . LYS B 1 60  ? 140.963 93.710  61.300  1.00 110.98 ? 60  LYS E CE  1 
ATOM 870  N NZ  . LYS B 1 60  ? 141.063 92.849  60.090  1.00 110.98 ? 60  LYS E NZ  1 
ATOM 871  N N   . LYS B 1 61  ? 138.876 92.495  67.914  1.00 122.88 ? 61  LYS E N   1 
ATOM 872  C CA  . LYS B 1 61  ? 137.706 92.166  68.722  1.00 122.88 ? 61  LYS E CA  1 
ATOM 873  C C   . LYS B 1 61  ? 137.379 93.291  69.696  1.00 122.88 ? 61  LYS E C   1 
ATOM 874  O O   . LYS B 1 61  ? 136.211 93.658  69.870  1.00 122.88 ? 61  LYS E O   1 
ATOM 875  C CB  . LYS B 1 61  ? 137.928 90.861  69.471  1.00 30.00  ? 61  LYS E CB  1 
ATOM 876  N N   . ILE B 1 62  ? 138.403 93.855  70.341  1.00 107.09 ? 62  ILE E N   1 
ATOM 877  C CA  . ILE B 1 62  ? 138.169 94.905  71.329  1.00 107.09 ? 62  ILE E CA  1 
ATOM 878  C C   . ILE B 1 62  ? 137.499 96.105  70.672  1.00 107.09 ? 62  ILE E C   1 
ATOM 879  O O   . ILE B 1 62  ? 136.513 96.647  71.184  1.00 107.09 ? 62  ILE E O   1 
ATOM 880  C CB  . ILE B 1 62  ? 139.490 95.301  72.014  1.00 107.09 ? 62  ILE E CB  1 
ATOM 881  C CG1 . ILE B 1 62  ? 140.203 94.053  72.541  1.00 107.09 ? 62  ILE E CG1 1 
ATOM 882  C CG2 . ILE B 1 62  ? 139.231 96.287  73.150  1.00 107.09 ? 62  ILE E CG2 1 
ATOM 883  C CD1 . ILE B 1 62  ? 141.304 94.339  73.541  1.00 107.09 ? 62  ILE E CD1 1 
ATOM 884  N N   . ILE B 1 63  ? 138.025 96.536  69.525  1.00 105.17 ? 63  ILE E N   1 
ATOM 885  C CA  . ILE B 1 63  ? 137.432 97.671  68.823  1.00 105.17 ? 63  ILE E CA  1 
ATOM 886  C C   . ILE B 1 63  ? 136.016 97.336  68.377  1.00 105.17 ? 63  ILE E C   1 
ATOM 887  O O   . ILE B 1 63  ? 135.092 98.144  68.531  1.00 105.17 ? 63  ILE E O   1 
ATOM 888  C CB  . ILE B 1 63  ? 138.319 98.087  67.635  1.00 105.17 ? 63  ILE E CB  1 
ATOM 889  C CG1 . ILE B 1 63  ? 139.677 98.587  68.131  1.00 105.17 ? 63  ILE E CG1 1 
ATOM 890  C CG2 . ILE B 1 63  ? 137.635 99.164  66.815  1.00 105.17 ? 63  ILE E CG2 1 
ATOM 891  C CD1 . ILE B 1 63  ? 140.788 98.437  67.119  1.00 105.17 ? 63  ILE E CD1 1 
ATOM 892  N N   . GLU B 1 64  ? 135.820 96.139  67.821  1.00 109.36 ? 64  GLU E N   1 
ATOM 893  C CA  . GLU B 1 64  ? 134.480 95.728  67.416  1.00 109.36 ? 64  GLU E CA  1 
ATOM 894  C C   . GLU B 1 64  ? 133.549 95.637  68.618  1.00 109.36 ? 64  GLU E C   1 
ATOM 895  O O   . GLU B 1 64  ? 132.383 96.044  68.543  1.00 109.36 ? 64  GLU E O   1 
ATOM 896  C CB  . GLU B 1 64  ? 134.532 94.398  66.680  1.00 30.00  ? 64  GLU E CB  1 
ATOM 897  N N   . LYS B 1 65  ? 134.046 95.106  69.736  1.00 111.40 ? 65  LYS E N   1 
ATOM 898  C CA  . LYS B 1 65  ? 133.220 94.993  70.935  1.00 111.40 ? 65  LYS E CA  1 
ATOM 899  C C   . LYS B 1 65  ? 132.794 96.366  71.438  1.00 111.40 ? 65  LYS E C   1 
ATOM 900  O O   . LYS B 1 65  ? 131.647 96.559  71.857  1.00 111.40 ? 65  LYS E O   1 
ATOM 901  C CB  . LYS B 1 65  ? 133.986 94.238  72.022  1.00 111.40 ? 65  LYS E CB  1 
ATOM 902  C CG  . LYS B 1 65  ? 133.104 93.574  73.067  1.00 111.40 ? 65  LYS E CG  1 
ATOM 903  C CD  . LYS B 1 65  ? 133.696 92.251  73.524  1.00 111.40 ? 65  LYS E CD  1 
ATOM 904  C CE  . LYS B 1 65  ? 133.116 91.810  74.857  1.00 111.40 ? 65  LYS E CE  1 
ATOM 905  N NZ  . LYS B 1 65  ? 133.721 90.534  75.330  1.00 111.40 ? 65  LYS E NZ  1 
ATOM 906  N N   . MET B 1 66  ? 133.711 97.336  71.405  1.00 102.03 ? 66  MET E N   1 
ATOM 907  C CA  . MET B 1 66  ? 133.403 98.661  71.931  1.00 102.03 ? 66  MET E CA  1 
ATOM 908  C C   . MET B 1 66  ? 132.302 99.338  71.124  1.00 102.03 ? 66  MET E C   1 
ATOM 909  O O   . MET B 1 66  ? 131.409 99.978  71.692  1.00 102.03 ? 66  MET E O   1 
ATOM 910  C CB  . MET B 1 66  ? 134.665 99.522  71.937  1.00 102.03 ? 66  MET E CB  1 
ATOM 911  C CG  . MET B 1 66  ? 135.535 99.334  73.169  1.00 102.03 ? 66  MET E CG  1 
ATOM 912  S SD  . MET B 1 66  ? 136.866 100.544 73.294  1.00 102.03 ? 66  MET E SD  1 
ATOM 913  C CE  . MET B 1 66  ? 137.599 100.420 71.664  1.00 102.03 ? 66  MET E CE  1 
ATOM 914  N N   . LEU B 1 67  ? 132.347 99.209  69.798  1.00 99.20  ? 67  LEU E N   1 
ATOM 915  C CA  . LEU B 1 67  ? 131.384 99.900  68.946  1.00 99.20  ? 67  LEU E CA  1 
ATOM 916  C C   . LEU B 1 67  ? 129.972 99.354  69.133  1.00 99.20  ? 67  LEU E C   1 
ATOM 917  O O   . LEU B 1 67  ? 129.003 100.120 69.173  1.00 99.20  ? 67  LEU E O   1 
ATOM 918  C CB  . LEU B 1 67  ? 131.805 99.784  67.481  1.00 99.20  ? 67  LEU E CB  1 
ATOM 919  C CG  . LEU B 1 67  ? 133.101 100.496 67.086  1.00 99.20  ? 67  LEU E CG  1 
ATOM 920  C CD1 . LEU B 1 67  ? 133.426 100.223 65.628  1.00 99.20  ? 67  LEU E CD1 1 
ATOM 921  C CD2 . LEU B 1 67  ? 133.004 101.990 67.343  1.00 99.20  ? 67  LEU E CD2 1 
ATOM 922  N N   . ASN B 1 68  ? 129.836 98.036  69.249  1.00 99.48  ? 68  ASN E N   1 
ATOM 923  C CA  . ASN B 1 68  ? 128.531 97.388  69.277  1.00 99.48  ? 68  ASN E CA  1 
ATOM 924  C C   . ASN B 1 68  ? 127.869 97.426  70.651  1.00 99.48  ? 68  ASN E C   1 
ATOM 925  O O   . ASN B 1 68  ? 126.944 96.643  70.895  1.00 99.48  ? 68  ASN E O   1 
ATOM 926  C CB  . ASN B 1 68  ? 128.662 95.937  68.805  1.00 99.48  ? 68  ASN E CB  1 
ATOM 927  C CG  . ASN B 1 68  ? 128.736 95.821  67.296  1.00 99.48  ? 68  ASN E CG  1 
ATOM 928  O OD1 . ASN B 1 68  ? 128.650 96.819  66.580  1.00 99.48  ? 68  ASN E OD1 1 
ATOM 929  N ND2 . ASN B 1 68  ? 128.898 94.599  66.803  1.00 99.48  ? 68  ASN E ND2 1 
ATOM 930  N N   . SER B 1 69  ? 128.310 98.304  71.545  1.00 97.29  ? 69  SER E N   1 
ATOM 931  C CA  . SER B 1 69  ? 127.698 98.418  72.864  1.00 97.29  ? 69  SER E CA  1 
ATOM 932  C C   . SER B 1 69  ? 126.210 98.732  72.742  1.00 97.29  ? 69  SER E C   1 
ATOM 933  O O   . SER B 1 69  ? 125.666 99.518  73.517  1.00 97.29  ? 69  SER E O   1 
ATOM 934  C CB  . SER B 1 69  ? 128.396 99.499  73.689  1.00 97.29  ? 69  SER E CB  1 
ATOM 935  O OG  . SER B 1 69  ? 128.027 99.414  75.055  1.00 97.29  ? 69  SER E OG  1 
ATOM 936  N N   . LEU C 2 90  ? 129.995 118.413 56.519  1.00 122.34 ? 34  LEU R N   1 
ATOM 937  C CA  . LEU C 2 90  ? 130.370 117.888 57.863  1.00 122.34 ? 34  LEU R CA  1 
ATOM 938  C C   . LEU C 2 90  ? 129.993 118.884 58.954  1.00 122.34 ? 34  LEU R C   1 
ATOM 939  O O   . LEU C 2 90  ? 130.851 119.363 59.694  1.00 122.34 ? 34  LEU R O   1 
ATOM 940  C CB  . LEU C 2 90  ? 131.868 117.582 57.923  1.00 122.34 ? 34  LEU R CB  1 
ATOM 941  C CG  . LEU C 2 90  ? 132.461 116.873 56.703  1.00 122.34 ? 34  LEU R CG  1 
ATOM 942  C CD1 . LEU C 2 90  ? 133.897 116.467 56.980  1.00 122.34 ? 34  LEU R CD1 1 
ATOM 943  C CD2 . LEU C 2 90  ? 131.628 115.661 56.316  1.00 122.34 ? 34  LEU R CD2 1 
ATOM 944  N N   . ASP C 2 91  ? 128.697 119.192 59.048  1.00 132.68 ? 35  ASP R N   1 
ATOM 945  C CA  . ASP C 2 91  ? 128.237 120.144 60.052  1.00 132.68 ? 35  ASP R CA  1 
ATOM 946  C C   . ASP C 2 91  ? 128.541 119.661 61.464  1.00 132.68 ? 35  ASP R C   1 
ATOM 947  O O   . ASP C 2 91  ? 128.743 120.478 62.369  1.00 132.68 ? 35  ASP R O   1 
ATOM 948  C CB  . ASP C 2 91  ? 126.738 120.393 59.888  1.00 132.68 ? 35  ASP R CB  1 
ATOM 949  C CG  . ASP C 2 91  ? 126.368 120.811 58.479  1.00 132.68 ? 35  ASP R CG  1 
ATOM 950  O OD1 . ASP C 2 91  ? 127.272 120.871 57.619  1.00 132.68 ? 35  ASP R OD1 1 
ATOM 951  O OD2 . ASP C 2 91  ? 125.174 121.081 58.230  1.00 132.68 ? 35  ASP R OD2 1 
ATOM 952  N N   . ALA C 2 92  ? 128.576 118.348 61.673  1.00 109.29 ? 36  ALA R N   1 
ATOM 953  C CA  . ALA C 2 92  ? 128.869 117.796 62.988  1.00 109.29 ? 36  ALA R CA  1 
ATOM 954  C C   . ALA C 2 92  ? 130.367 117.848 63.253  1.00 109.29 ? 36  ALA R C   1 
ATOM 955  O O   . ALA C 2 92  ? 131.172 117.477 62.394  1.00 109.29 ? 36  ALA R O   1 
ATOM 956  C CB  . ALA C 2 92  ? 128.366 116.357 63.086  1.00 109.29 ? 36  ALA R CB  1 
ATOM 957  N N   . ALA C 2 93  ? 130.738 118.309 64.443  1.00 94.69  ? 37  ALA R N   1 
ATOM 958  C CA  . ALA C 2 93  ? 132.135 118.381 64.844  1.00 94.69  ? 37  ALA R CA  1 
ATOM 959  C C   . ALA C 2 93  ? 132.196 118.381 66.364  1.00 94.69  ? 37  ALA R C   1 
ATOM 960  O O   . ALA C 2 93  ? 131.219 118.751 67.025  1.00 94.69  ? 37  ALA R O   1 
ATOM 961  C CB  . ALA C 2 93  ? 132.816 119.636 64.276  1.00 94.69  ? 37  ALA R CB  1 
ATOM 962  N N   . PRO C 2 94  ? 133.322 117.972 66.947  1.00 95.14  ? 38  PRO R N   1 
ATOM 963  C CA  . PRO C 2 94  ? 133.423 117.966 68.410  1.00 95.14  ? 38  PRO R CA  1 
ATOM 964  C C   . PRO C 2 94  ? 133.258 119.363 68.986  1.00 95.14  ? 38  PRO R C   1 
ATOM 965  O O   . PRO C 2 94  ? 133.703 120.354 68.405  1.00 95.14  ? 38  PRO R O   1 
ATOM 966  C CB  . PRO C 2 94  ? 134.830 117.412 68.670  1.00 95.14  ? 38  PRO R CB  1 
ATOM 967  C CG  . PRO C 2 94  ? 135.222 116.727 67.411  1.00 95.14  ? 38  PRO R CG  1 
ATOM 968  C CD  . PRO C 2 94  ? 134.554 117.480 66.309  1.00 95.14  ? 38  PRO R CD  1 
ATOM 969  N N   . CYS C 2 95  ? 132.607 119.432 70.148  1.00 115.52 ? 39  CYS R N   1 
ATOM 970  C CA  . CYS C 2 95  ? 132.440 120.691 70.875  1.00 115.52 ? 39  CYS R CA  1 
ATOM 971  C C   . CYS C 2 95  ? 133.656 120.878 71.776  1.00 115.52 ? 39  CYS R C   1 
ATOM 972  O O   . CYS C 2 95  ? 133.662 120.529 72.958  1.00 115.52 ? 39  CYS R O   1 
ATOM 973  C CB  . CYS C 2 95  ? 131.137 120.685 71.665  1.00 115.52 ? 39  CYS R CB  1 
ATOM 974  S SG  . CYS C 2 95  ? 130.935 122.080 72.798  1.00 115.52 ? 39  CYS R SG  1 
ATOM 975  N N   . GLU C 2 96  ? 134.708 121.442 71.193  1.00 122.90 ? 40  GLU R N   1 
ATOM 976  C CA  . GLU C 2 96  ? 135.960 121.591 71.915  1.00 122.90 ? 40  GLU R CA  1 
ATOM 977  C C   . GLU C 2 96  ? 135.757 122.490 73.133  1.00 122.90 ? 40  GLU R C   1 
ATOM 978  O O   . GLU C 2 96  ? 135.172 123.573 73.013  1.00 122.90 ? 40  GLU R O   1 
ATOM 979  C CB  . GLU C 2 96  ? 137.036 122.185 71.005  1.00 122.90 ? 40  GLU R CB  1 
ATOM 980  C CG  . GLU C 2 96  ? 137.371 121.329 69.796  1.00 122.90 ? 40  GLU R CG  1 
ATOM 981  C CD  . GLU C 2 96  ? 138.362 122.001 68.866  1.00 122.90 ? 40  GLU R CD  1 
ATOM 982  O OE1 . GLU C 2 96  ? 138.772 123.145 69.157  1.00 122.90 ? 40  GLU R OE1 1 
ATOM 983  O OE2 . GLU C 2 96  ? 138.731 121.387 67.843  1.00 122.90 ? 40  GLU R OE2 1 
ATOM 984  N N   . PRO C 2 97  ? 136.219 122.083 74.314  1.00 114.92 ? 41  PRO R N   1 
ATOM 985  C CA  . PRO C 2 97  ? 136.114 122.966 75.479  1.00 114.92 ? 41  PRO R CA  1 
ATOM 986  C C   . PRO C 2 97  ? 136.994 124.194 75.320  1.00 114.92 ? 41  PRO R C   1 
ATOM 987  O O   . PRO C 2 97  ? 138.048 124.155 74.682  1.00 114.92 ? 41  PRO R O   1 
ATOM 988  C CB  . PRO C 2 97  ? 136.586 122.085 76.640  1.00 114.92 ? 41  PRO R CB  1 
ATOM 989  C CG  . PRO C 2 97  ? 137.473 121.077 76.010  1.00 114.92 ? 41  PRO R CG  1 
ATOM 990  C CD  . PRO C 2 97  ? 136.909 120.822 74.642  1.00 114.92 ? 41  PRO R CD  1 
ATOM 991  N N   . GLU C 2 98  ? 136.544 125.297 75.912  1.00 118.34 ? 42  GLU R N   1 
ATOM 992  C CA  . GLU C 2 98  ? 137.266 126.562 75.881  1.00 118.34 ? 42  GLU R CA  1 
ATOM 993  C C   . GLU C 2 98  ? 137.626 126.950 77.306  1.00 118.34 ? 42  GLU R C   1 
ATOM 994  O O   . GLU C 2 98  ? 136.744 127.067 78.163  1.00 118.34 ? 42  GLU R O   1 
ATOM 995  C CB  . GLU C 2 98  ? 136.440 127.648 75.208  1.00 30.00  ? 42  GLU R CB  1 
ATOM 996  N N   . SER C 2 99  ? 138.918 127.148 77.556  1.00 121.20 ? 43  SER R N   1 
ATOM 997  C CA  . SER C 2 99  ? 139.420 127.519 78.871  1.00 121.20 ? 43  SER R CA  1 
ATOM 998  C C   . SER C 2 99  ? 140.371 128.697 78.735  1.00 121.20 ? 43  SER R C   1 
ATOM 999  O O   . SER C 2 99  ? 141.155 128.767 77.784  1.00 121.20 ? 43  SER R O   1 
ATOM 1000 C CB  . SER C 2 99  ? 140.138 126.343 79.544  1.00 121.20 ? 43  SER R CB  1 
ATOM 1001 O OG  . SER C 2 99  ? 141.136 125.805 78.694  1.00 121.20 ? 43  SER R OG  1 
ATOM 1002 N N   . LEU C 2 100 ? 140.295 129.620 79.690  1.00 122.33 ? 44  LEU R N   1 
ATOM 1003 C CA  . LEU C 2 100 ? 141.151 130.798 79.725  1.00 122.33 ? 44  LEU R CA  1 
ATOM 1004 C C   . LEU C 2 100 ? 142.017 130.743 80.973  1.00 122.33 ? 44  LEU R C   1 
ATOM 1005 O O   . LEU C 2 100 ? 141.510 130.514 82.076  1.00 122.33 ? 44  LEU R O   1 
ATOM 1006 C CB  . LEU C 2 100 ? 140.324 132.074 79.689  1.00 30.00  ? 44  LEU R CB  1 
ATOM 1007 N N   . GLU C 2 101 ? 143.324 130.955 80.795  1.00 121.74 ? 45  GLU R N   1 
ATOM 1008 C CA  . GLU C 2 101 ? 144.244 130.914 81.923  1.00 121.74 ? 45  GLU R CA  1 
ATOM 1009 C C   . GLU C 2 101 ? 143.955 132.021 82.927  1.00 121.74 ? 45  GLU R C   1 
ATOM 1010 O O   . GLU C 2 101 ? 144.311 131.893 84.103  1.00 121.74 ? 45  GLU R O   1 
ATOM 1011 C CB  . GLU C 2 101 ? 145.681 131.007 81.434  1.00 30.00  ? 45  GLU R CB  1 
ATOM 1012 N N   . ILE C 2 102 ? 143.305 133.104 82.497  1.00 116.92 ? 46  ILE R N   1 
ATOM 1013 C CA  . ILE C 2 102 ? 143.068 134.234 83.390  1.00 116.92 ? 46  ILE R CA  1 
ATOM 1014 C C   . ILE C 2 102 ? 142.267 133.788 84.607  1.00 116.92 ? 46  ILE R C   1 
ATOM 1015 O O   . ILE C 2 102 ? 142.584 134.146 85.748  1.00 116.92 ? 46  ILE R O   1 
ATOM 1016 C CB  . ILE C 2 102 ? 142.357 135.372 82.634  1.00 116.92 ? 46  ILE R CB  1 
ATOM 1017 C CG1 . ILE C 2 102 ? 143.249 135.883 81.498  1.00 116.92 ? 46  ILE R CG1 1 
ATOM 1018 C CG2 . ILE C 2 102 ? 141.990 136.502 83.595  1.00 116.92 ? 46  ILE R CG2 1 
ATOM 1019 C CD1 . ILE C 2 102 ? 142.649 137.021 80.695  1.00 116.92 ? 46  ILE R CD1 1 
ATOM 1020 N N   . ASN C 2 103 ? 141.218 132.998 84.381  1.00 118.62 ? 47  ASN R N   1 
ATOM 1021 C CA  . ASN C 2 103 ? 140.319 132.623 85.467  1.00 118.62 ? 47  ASN R CA  1 
ATOM 1022 C C   . ASN C 2 103 ? 141.027 131.781 86.523  1.00 118.62 ? 47  ASN R C   1 
ATOM 1023 O O   . ASN C 2 103 ? 140.845 131.993 87.727  1.00 118.62 ? 47  ASN R O   1 
ATOM 1024 C CB  . ASN C 2 103 ? 139.116 131.866 84.903  1.00 118.62 ? 47  ASN R CB  1 
ATOM 1025 C CG  . ASN C 2 103 ? 138.225 132.743 84.046  1.00 118.62 ? 47  ASN R CG  1 
ATOM 1026 O OD1 . ASN C 2 103 ? 137.694 133.751 84.511  1.00 118.62 ? 47  ASN R OD1 1 
ATOM 1027 N ND2 . ASN C 2 103 ? 138.056 132.362 82.785  1.00 118.62 ? 47  ASN R ND2 1 
ATOM 1028 N N   . LYS C 2 104 ? 141.844 130.817 86.092  1.00 111.09 ? 48  LYS R N   1 
ATOM 1029 C CA  . LYS C 2 104 ? 142.278 129.765 87.007  1.00 111.09 ? 48  LYS R CA  1 
ATOM 1030 C C   . LYS C 2 104 ? 143.189 130.308 88.106  1.00 111.09 ? 48  LYS R C   1 
ATOM 1031 O O   . LYS C 2 104 ? 143.003 129.991 89.287  1.00 111.09 ? 48  LYS R O   1 
ATOM 1032 C CB  . LYS C 2 104 ? 142.956 128.632 86.229  1.00 111.09 ? 48  LYS R CB  1 
ATOM 1033 C CG  . LYS C 2 104 ? 144.311 128.949 85.613  1.00 111.09 ? 48  LYS R CG  1 
ATOM 1034 C CD  . LYS C 2 104 ? 144.984 127.672 85.126  1.00 111.09 ? 48  LYS R CD  1 
ATOM 1035 C CE  . LYS C 2 104 ? 145.868 127.916 83.915  1.00 111.09 ? 48  LYS R CE  1 
ATOM 1036 N NZ  . LYS C 2 104 ? 146.136 126.661 83.158  1.00 111.09 ? 48  LYS R NZ  1 
ATOM 1037 N N   . TYR C 2 105 ? 144.179 131.131 87.750  1.00 105.91 ? 49  TYR R N   1 
ATOM 1038 C CA  . TYR C 2 105 ? 145.147 131.555 88.759  1.00 105.91 ? 49  TYR R CA  1 
ATOM 1039 C C   . TYR C 2 105 ? 144.558 132.617 89.680  1.00 105.91 ? 49  TYR R C   1 
ATOM 1040 O O   . TYR C 2 105 ? 144.915 132.689 90.861  1.00 105.91 ? 49  TYR R O   1 
ATOM 1041 C CB  . TYR C 2 105 ? 146.436 132.056 88.103  1.00 105.91 ? 49  TYR R CB  1 
ATOM 1042 C CG  . TYR C 2 105 ? 146.284 133.213 87.142  1.00 105.91 ? 49  TYR R CG  1 
ATOM 1043 C CD1 . TYR C 2 105 ? 146.073 134.505 87.603  1.00 105.91 ? 49  TYR R CD1 1 
ATOM 1044 C CD2 . TYR C 2 105 ? 146.391 133.017 85.773  1.00 105.91 ? 49  TYR R CD2 1 
ATOM 1045 C CE1 . TYR C 2 105 ? 145.946 135.565 86.726  1.00 105.91 ? 49  TYR R CE1 1 
ATOM 1046 C CE2 . TYR C 2 105 ? 146.268 134.068 84.889  1.00 105.91 ? 49  TYR R CE2 1 
ATOM 1047 C CZ  . TYR C 2 105 ? 146.046 135.340 85.370  1.00 105.91 ? 49  TYR R CZ  1 
ATOM 1048 O OH  . TYR C 2 105 ? 145.922 136.392 84.491  1.00 105.91 ? 49  TYR R OH  1 
ATOM 1049 N N   . PHE C 2 106 ? 143.652 133.450 89.164  1.00 98.78  ? 50  PHE R N   1 
ATOM 1050 C CA  . PHE C 2 106 ? 142.985 134.421 90.026  1.00 98.78  ? 50  PHE R CA  1 
ATOM 1051 C C   . PHE C 2 106 ? 142.142 133.723 91.083  1.00 98.78  ? 50  PHE R C   1 
ATOM 1052 O O   . PHE C 2 106 ? 141.965 134.242 92.192  1.00 98.78  ? 50  PHE R O   1 
ATOM 1053 C CB  . PHE C 2 106 ? 142.121 135.366 89.191  1.00 98.78  ? 50  PHE R CB  1 
ATOM 1054 C CG  . PHE C 2 106 ? 142.756 136.701 88.938  1.00 98.78  ? 50  PHE R CG  1 
ATOM 1055 C CD1 . PHE C 2 106 ? 142.989 137.580 89.983  1.00 98.78  ? 50  PHE R CD1 1 
ATOM 1056 C CD2 . PHE C 2 106 ? 143.123 137.079 87.658  1.00 98.78  ? 50  PHE R CD2 1 
ATOM 1057 C CE1 . PHE C 2 106 ? 143.574 138.810 89.755  1.00 98.78  ? 50  PHE R CE1 1 
ATOM 1058 C CE2 . PHE C 2 106 ? 143.709 138.307 87.425  1.00 98.78  ? 50  PHE R CE2 1 
ATOM 1059 C CZ  . PHE C 2 106 ? 143.935 139.173 88.474  1.00 98.78  ? 50  PHE R CZ  1 
ATOM 1060 N N   . VAL C 2 107 ? 141.611 132.544 90.758  1.00 87.14  ? 51  VAL R N   1 
ATOM 1061 C CA  . VAL C 2 107 ? 140.799 131.803 91.716  1.00 87.14  ? 51  VAL R CA  1 
ATOM 1062 C C   . VAL C 2 107 ? 141.644 131.359 92.903  1.00 87.14  ? 51  VAL R C   1 
ATOM 1063 O O   . VAL C 2 107 ? 141.162 131.310 94.041  1.00 87.14  ? 51  VAL R O   1 
ATOM 1064 C CB  . VAL C 2 107 ? 140.123 130.608 91.018  1.00 87.14  ? 51  VAL R CB  1 
ATOM 1065 C CG1 . VAL C 2 107 ? 139.718 129.548 92.031  1.00 87.14  ? 51  VAL R CG1 1 
ATOM 1066 C CG2 . VAL C 2 107 ? 138.918 131.077 90.220  1.00 87.14  ? 51  VAL R CG2 1 
ATOM 1067 N N   . VAL C 2 108 ? 142.914 131.026 92.661  1.00 82.79  ? 52  VAL R N   1 
ATOM 1068 C CA  . VAL C 2 108 ? 143.772 130.512 93.728  1.00 82.79  ? 52  VAL R CA  1 
ATOM 1069 C C   . VAL C 2 108 ? 143.896 131.540 94.847  1.00 82.79  ? 52  VAL R C   1 
ATOM 1070 O O   . VAL C 2 108 ? 143.759 131.219 96.033  1.00 82.79  ? 52  VAL R O   1 
ATOM 1071 C CB  . VAL C 2 108 ? 145.154 130.130 93.171  1.00 82.79  ? 52  VAL R CB  1 
ATOM 1072 C CG1 . VAL C 2 108 ? 146.064 129.647 94.291  1.00 82.79  ? 52  VAL R CG1 1 
ATOM 1073 C CG2 . VAL C 2 108 ? 145.020 129.067 92.096  1.00 82.79  ? 52  VAL R CG2 1 
ATOM 1074 N N   . ILE C 2 109 ? 144.159 132.795 94.481  1.00 81.94  ? 53  ILE R N   1 
ATOM 1075 C CA  . ILE C 2 109 ? 144.314 133.840 95.489  1.00 81.94  ? 53  ILE R CA  1 
ATOM 1076 C C   . ILE C 2 109 ? 143.014 134.028 96.259  1.00 81.94  ? 53  ILE R C   1 
ATOM 1077 O O   . ILE C 2 109 ? 143.018 134.160 97.489  1.00 81.94  ? 53  ILE R O   1 
ATOM 1078 C CB  . ILE C 2 109 ? 144.787 135.150 94.831  1.00 81.94  ? 53  ILE R CB  1 
ATOM 1079 C CG1 . ILE C 2 109 ? 146.280 135.043 94.499  1.00 81.94  ? 53  ILE R CG1 1 
ATOM 1080 C CG2 . ILE C 2 109 ? 144.489 136.345 95.743  1.00 81.94  ? 53  ILE R CG2 1 
ATOM 1081 C CD1 . ILE C 2 109 ? 146.941 136.343 94.086  1.00 81.94  ? 53  ILE R CD1 1 
ATOM 1082 N N   . ILE C 2 110 ? 141.881 134.043 95.552  1.00 81.94  ? 54  ILE R N   1 
ATOM 1083 C CA  . ILE C 2 110 ? 140.593 134.161 96.223  1.00 81.94  ? 54  ILE R CA  1 
ATOM 1084 C C   . ILE C 2 110 ? 140.360 132.998 97.174  1.00 81.94  ? 54  ILE R C   1 
ATOM 1085 O O   . ILE C 2 110 ? 139.865 133.202 98.288  1.00 81.94  ? 54  ILE R O   1 
ATOM 1086 C CB  . ILE C 2 110 ? 139.453 134.246 95.191  1.00 81.94  ? 54  ILE R CB  1 
ATOM 1087 C CG1 . ILE C 2 110 ? 139.588 135.514 94.342  1.00 81.94  ? 54  ILE R CG1 1 
ATOM 1088 C CG2 . ILE C 2 110 ? 138.102 134.209 95.889  1.00 81.94  ? 54  ILE R CG2 1 
ATOM 1089 C CD1 . ILE C 2 110 ? 139.357 136.809 95.102  1.00 81.94  ? 54  ILE R CD1 1 
ATOM 1090 N N   . TYR C 2 111 ? 140.703 131.776 96.764  1.00 82.71  ? 55  TYR R N   1 
ATOM 1091 C CA  . TYR C 2 111 ? 140.616 130.637 97.669  1.00 82.71  ? 55  TYR R CA  1 
ATOM 1092 C C   . TYR C 2 111 ? 141.554 130.789 98.858  1.00 82.71  ? 55  TYR R C   1 
ATOM 1093 O O   . TYR C 2 111 ? 141.165 130.487 99.992  1.00 82.71  ? 55  TYR R O   1 
ATOM 1094 C CB  . TYR C 2 111 ? 140.939 129.346 96.917  1.00 82.71  ? 55  TYR R CB  1 
ATOM 1095 C CG  . TYR C 2 111 ? 139.730 128.622 96.372  1.00 82.71  ? 55  TYR R CG  1 
ATOM 1096 C CD1 . TYR C 2 111 ? 138.955 129.182 95.369  1.00 82.71  ? 55  TYR R CD1 1 
ATOM 1097 C CD2 . TYR C 2 111 ? 139.376 127.369 96.849  1.00 82.71  ? 55  TYR R CD2 1 
ATOM 1098 C CE1 . TYR C 2 111 ? 137.853 128.521 94.865  1.00 82.71  ? 55  TYR R CE1 1 
ATOM 1099 C CE2 . TYR C 2 111 ? 138.277 126.700 96.351  1.00 82.71  ? 55  TYR R CE2 1 
ATOM 1100 C CZ  . TYR C 2 111 ? 137.520 127.280 95.359  1.00 82.71  ? 55  TYR R CZ  1 
ATOM 1101 O OH  . TYR C 2 111 ? 136.424 126.616 94.859  1.00 82.71  ? 55  TYR R OH  1 
ATOM 1102 N N   . ALA C 2 112 ? 142.784 131.250 98.623  1.00 81.94  ? 56  ALA R N   1 
ATOM 1103 C CA  . ALA C 2 112 ? 143.740 131.422 99.711  1.00 81.94  ? 56  ALA R CA  1 
ATOM 1104 C C   . ALA C 2 112 ? 143.283 132.491 100.696 1.00 81.94  ? 56  ALA R C   1 
ATOM 1105 O O   . ALA C 2 112 ? 143.418 132.317 101.912 1.00 81.94  ? 56  ALA R O   1 
ATOM 1106 C CB  . ALA C 2 112 ? 145.116 131.776 99.147  1.00 81.94  ? 56  ALA R CB  1 
ATOM 1107 N N   . LEU C 2 113 ? 142.749 133.606 100.193 1.00 82.68  ? 57  LEU R N   1 
ATOM 1108 C CA  . LEU C 2 113 ? 142.287 134.665 101.083 1.00 82.68  ? 57  LEU R CA  1 
ATOM 1109 C C   . LEU C 2 113 ? 141.153 134.173 101.972 1.00 82.68  ? 57  LEU R C   1 
ATOM 1110 O O   . LEU C 2 113 ? 141.120 134.469 103.172 1.00 82.68  ? 57  LEU R O   1 
ATOM 1111 C CB  . LEU C 2 113 ? 141.848 135.878 100.263 1.00 82.68  ? 57  LEU R CB  1 
ATOM 1112 C CG  . LEU C 2 113 ? 141.255 137.057 101.035 1.00 82.68  ? 57  LEU R CG  1 
ATOM 1113 C CD1 . LEU C 2 113 ? 142.352 137.809 101.767 1.00 82.68  ? 57  LEU R CD1 1 
ATOM 1114 C CD2 . LEU C 2 113 ? 140.504 137.986 100.095 1.00 82.68  ? 57  LEU R CD2 1 
ATOM 1115 N N   . VAL C 2 114 ? 140.213 133.419 101.401 1.00 83.37  ? 58  VAL R N   1 
ATOM 1116 C CA  . VAL C 2 114 ? 139.125 132.859 102.196 1.00 83.37  ? 58  VAL R CA  1 
ATOM 1117 C C   . VAL C 2 114 ? 139.672 131.895 103.241 1.00 83.37  ? 58  VAL R C   1 
ATOM 1118 O O   . VAL C 2 114 ? 139.160 131.819 104.364 1.00 83.37  ? 58  VAL R O   1 
ATOM 1119 C CB  . VAL C 2 114 ? 138.094 132.179 101.278 1.00 83.37  ? 58  VAL R CB  1 
ATOM 1120 C CG1 . VAL C 2 114 ? 137.034 131.461 102.098 1.00 83.37  ? 58  VAL R CG1 1 
ATOM 1121 C CG2 . VAL C 2 114 ? 137.447 133.203 100.360 1.00 83.37  ? 58  VAL R CG2 1 
ATOM 1122 N N   . PHE C 2 115 ? 140.713 131.141 102.888 1.00 81.94  ? 59  PHE R N   1 
ATOM 1123 C CA  . PHE C 2 115 ? 141.297 130.194 103.833 1.00 81.94  ? 59  PHE R CA  1 
ATOM 1124 C C   . PHE C 2 115 ? 141.820 130.908 105.073 1.00 81.94  ? 59  PHE R C   1 
ATOM 1125 O O   . PHE C 2 115 ? 141.575 130.473 106.204 1.00 81.94  ? 59  PHE R O   1 
ATOM 1126 C CB  . PHE C 2 115 ? 142.418 129.409 103.151 1.00 81.94  ? 59  PHE R CB  1 
ATOM 1127 C CG  . PHE C 2 115 ? 143.268 128.615 104.101 1.00 81.94  ? 59  PHE R CG  1 
ATOM 1128 C CD1 . PHE C 2 115 ? 142.710 127.629 104.892 1.00 81.94  ? 59  PHE R CD1 1 
ATOM 1129 C CD2 . PHE C 2 115 ? 144.626 128.857 104.199 1.00 81.94  ? 59  PHE R CD2 1 
ATOM 1130 C CE1 . PHE C 2 115 ? 143.491 126.899 105.764 1.00 81.94  ? 59  PHE R CE1 1 
ATOM 1131 C CE2 . PHE C 2 115 ? 145.411 128.130 105.070 1.00 81.94  ? 59  PHE R CE2 1 
ATOM 1132 C CZ  . PHE C 2 115 ? 144.843 127.150 105.852 1.00 81.94  ? 59  PHE R CZ  1 
ATOM 1133 N N   . LEU C 2 116 ? 142.545 132.012 104.882 1.00 84.77  ? 60  LEU R N   1 
ATOM 1134 C CA  . LEU C 2 116 ? 143.143 132.708 106.016 1.00 84.77  ? 60  LEU R CA  1 
ATOM 1135 C C   . LEU C 2 116 ? 142.075 133.259 106.953 1.00 84.77  ? 60  LEU R C   1 
ATOM 1136 O O   . LEU C 2 116 ? 142.171 133.116 108.177 1.00 84.77  ? 60  LEU R O   1 
ATOM 1137 C CB  . LEU C 2 116 ? 144.051 133.834 105.519 1.00 84.77  ? 60  LEU R CB  1 
ATOM 1138 C CG  . LEU C 2 116 ? 145.341 133.402 104.820 1.00 84.77  ? 60  LEU R CG  1 
ATOM 1139 C CD1 . LEU C 2 116 ? 146.028 134.602 104.188 1.00 84.77  ? 60  LEU R CD1 1 
ATOM 1140 C CD2 . LEU C 2 116 ? 146.274 132.700 105.793 1.00 84.77  ? 60  LEU R CD2 1 
ATOM 1141 N N   . LEU C 2 117 ? 141.043 133.895 106.393 1.00 81.94  ? 61  LEU R N   1 
ATOM 1142 C CA  . LEU C 2 117 ? 140.030 134.528 107.230 1.00 81.94  ? 61  LEU R CA  1 
ATOM 1143 C C   . LEU C 2 117 ? 139.229 133.496 108.014 1.00 81.94  ? 61  LEU R C   1 
ATOM 1144 O O   . LEU C 2 117 ? 139.012 133.655 109.221 1.00 81.94  ? 61  LEU R O   1 
ATOM 1145 C CB  . LEU C 2 117 ? 139.104 135.385 106.368 1.00 81.94  ? 61  LEU R CB  1 
ATOM 1146 C CG  . LEU C 2 117 ? 139.766 136.549 105.629 1.00 81.94  ? 61  LEU R CG  1 
ATOM 1147 C CD1 . LEU C 2 117 ? 138.785 137.186 104.659 1.00 81.94  ? 61  LEU R CD1 1 
ATOM 1148 C CD2 . LEU C 2 117 ? 140.296 137.580 106.611 1.00 81.94  ? 61  LEU R CD2 1 
ATOM 1149 N N   . SER C 2 118 ? 138.781 132.429 107.348 1.00 82.71  ? 62  SER R N   1 
ATOM 1150 C CA  . SER C 2 118 ? 137.995 131.411 108.039 1.00 82.71  ? 62  SER R CA  1 
ATOM 1151 C C   . SER C 2 118 ? 138.809 130.736 109.134 1.00 82.71  ? 62  SER R C   1 
ATOM 1152 O O   . SER C 2 118 ? 138.291 130.469 110.225 1.00 82.71  ? 62  SER R O   1 
ATOM 1153 C CB  . SER C 2 118 ? 137.479 130.376 107.040 1.00 82.71  ? 62  SER R CB  1 
ATOM 1154 O OG  . SER C 2 118 ? 136.494 130.937 106.190 1.00 82.71  ? 62  SER R OG  1 
ATOM 1155 N N   . LEU C 2 119 ? 140.082 130.449 108.863 1.00 81.94  ? 63  LEU R N   1 
ATOM 1156 C CA  . LEU C 2 119 ? 140.926 129.818 109.871 1.00 81.94  ? 63  LEU R CA  1 
ATOM 1157 C C   . LEU C 2 119 ? 141.060 130.706 111.101 1.00 81.94  ? 63  LEU R C   1 
ATOM 1158 O O   . LEU C 2 119 ? 140.972 130.231 112.239 1.00 81.94  ? 63  LEU R O   1 
ATOM 1159 C CB  . LEU C 2 119 ? 142.300 129.509 109.274 1.00 81.94  ? 63  LEU R CB  1 
ATOM 1160 C CG  . LEU C 2 119 ? 143.314 128.833 110.199 1.00 81.94  ? 63  LEU R CG  1 
ATOM 1161 C CD1 . LEU C 2 119 ? 142.792 127.491 110.686 1.00 81.94  ? 63  LEU R CD1 1 
ATOM 1162 C CD2 . LEU C 2 119 ? 144.646 128.665 109.488 1.00 81.94  ? 63  LEU R CD2 1 
ATOM 1163 N N   . LEU C 2 120 ? 141.273 132.006 110.892 1.00 81.94  ? 64  LEU R N   1 
ATOM 1164 C CA  . LEU C 2 120 ? 141.401 132.926 112.017 1.00 81.94  ? 64  LEU R CA  1 
ATOM 1165 C C   . LEU C 2 120 ? 140.056 133.153 112.697 1.00 81.94  ? 64  LEU R C   1 
ATOM 1166 O O   . LEU C 2 120 ? 139.956 133.110 113.929 1.00 81.94  ? 64  LEU R O   1 
ATOM 1167 C CB  . LEU C 2 120 ? 141.993 134.252 111.538 1.00 81.94  ? 64  LEU R CB  1 
ATOM 1168 C CG  . LEU C 2 120 ? 142.152 135.355 112.587 1.00 81.94  ? 64  LEU R CG  1 
ATOM 1169 C CD1 . LEU C 2 120 ? 143.208 134.974 113.611 1.00 81.94  ? 64  LEU R CD1 1 
ATOM 1170 C CD2 . LEU C 2 120 ? 142.503 136.675 111.920 1.00 81.94  ? 64  LEU R CD2 1 
ATOM 1171 N N   . GLY C 2 121 ? 139.008 133.393 111.909 1.00 83.16  ? 65  GLY R N   1 
ATOM 1172 C CA  . GLY C 2 121 ? 137.716 133.716 112.495 1.00 83.16  ? 65  GLY R CA  1 
ATOM 1173 C C   . GLY C 2 121 ? 137.143 132.577 113.315 1.00 83.16  ? 65  GLY R C   1 
ATOM 1174 O O   . GLY C 2 121 ? 136.664 132.778 114.434 1.00 83.16  ? 65  GLY R O   1 
ATOM 1175 N N   . ASN C 2 122 ? 137.183 131.361 112.768 1.00 84.93  ? 66  ASN R N   1 
ATOM 1176 C CA  . ASN C 2 122 ? 136.613 130.220 113.476 1.00 84.93  ? 66  ASN R CA  1 
ATOM 1177 C C   . ASN C 2 122 ? 137.362 129.944 114.773 1.00 84.93  ? 66  ASN R C   1 
ATOM 1178 O O   . ASN C 2 122 ? 136.750 129.608 115.793 1.00 84.93  ? 66  ASN R O   1 
ATOM 1179 C CB  . ASN C 2 122 ? 136.623 128.987 112.575 1.00 84.93  ? 66  ASN R CB  1 
ATOM 1180 C CG  . ASN C 2 122 ? 135.603 129.075 111.458 1.00 84.93  ? 66  ASN R CG  1 
ATOM 1181 O OD1 . ASN C 2 122 ? 134.610 129.793 111.565 1.00 84.93  ? 66  ASN R OD1 1 
ATOM 1182 N ND2 . ASN C 2 122 ? 135.842 128.339 110.380 1.00 84.93  ? 66  ASN R ND2 1 
ATOM 1183 N N   . SER C 2 123 ? 138.689 130.079 114.756 1.00 90.53  ? 67  SER R N   1 
ATOM 1184 C CA  . SER C 2 123 ? 139.466 129.828 115.965 1.00 90.53  ? 67  SER R CA  1 
ATOM 1185 C C   . SER C 2 123 ? 139.082 130.797 117.076 1.00 90.53  ? 67  SER R C   1 
ATOM 1186 O O   . SER C 2 123 ? 138.967 130.399 118.241 1.00 90.53  ? 67  SER R O   1 
ATOM 1187 C CB  . SER C 2 123 ? 140.959 129.927 115.659 1.00 90.53  ? 67  SER R CB  1 
ATOM 1188 O OG  . SER C 2 123 ? 141.349 128.953 114.707 1.00 90.53  ? 67  SER R OG  1 
ATOM 1189 N N   . LEU C 2 124 ? 138.881 132.073 116.739 1.00 81.94  ? 68  LEU R N   1 
ATOM 1190 C CA  . LEU C 2 124 ? 138.474 133.041 117.752 1.00 81.94  ? 68  LEU R CA  1 
ATOM 1191 C C   . LEU C 2 124 ? 137.131 132.663 118.364 1.00 81.94  ? 68  LEU R C   1 
ATOM 1192 O O   . LEU C 2 124 ? 136.955 132.744 119.585 1.00 81.94  ? 68  LEU R O   1 
ATOM 1193 C CB  . LEU C 2 124 ? 138.413 134.442 117.145 1.00 81.94  ? 68  LEU R CB  1 
ATOM 1194 C CG  . LEU C 2 124 ? 139.766 135.093 116.853 1.00 81.94  ? 68  LEU R CG  1 
ATOM 1195 C CD1 . LEU C 2 124 ? 139.590 136.318 115.974 1.00 81.94  ? 68  LEU R CD1 1 
ATOM 1196 C CD2 . LEU C 2 124 ? 140.477 135.461 118.144 1.00 81.94  ? 68  LEU R CD2 1 
ATOM 1197 N N   . VAL C 2 125 ? 136.174 132.242 117.535 1.00 81.94  ? 69  VAL R N   1 
ATOM 1198 C CA  . VAL C 2 125 ? 134.886 131.801 118.061 1.00 81.94  ? 69  VAL R CA  1 
ATOM 1199 C C   . VAL C 2 125 ? 135.077 130.603 118.981 1.00 81.94  ? 69  VAL R C   1 
ATOM 1200 O O   . VAL C 2 125 ? 134.483 130.529 120.063 1.00 81.94  ? 69  VAL R O   1 
ATOM 1201 C CB  . VAL C 2 125 ? 133.919 131.482 116.906 1.00 81.94  ? 69  VAL R CB  1 
ATOM 1202 C CG1 . VAL C 2 125 ? 132.764 130.620 117.394 1.00 81.94  ? 69  VAL R CG1 1 
ATOM 1203 C CG2 . VAL C 2 125 ? 133.403 132.766 116.280 1.00 81.94  ? 69  VAL R CG2 1 
ATOM 1204 N N   . MET C 2 126 ? 135.905 129.643 118.564 1.00 84.06  ? 70  MET R N   1 
ATOM 1205 C CA  . MET C 2 126 ? 136.214 128.512 119.431 1.00 84.06  ? 70  MET R CA  1 
ATOM 1206 C C   . MET C 2 126 ? 136.952 128.967 120.683 1.00 84.06  ? 70  MET R C   1 
ATOM 1207 O O   . MET C 2 126 ? 136.673 128.486 121.787 1.00 84.06  ? 70  MET R O   1 
ATOM 1208 C CB  . MET C 2 126 ? 137.049 127.482 118.672 1.00 84.06  ? 70  MET R CB  1 
ATOM 1209 C CG  . MET C 2 126 ? 136.251 126.313 118.128 1.00 84.06  ? 70  MET R CG  1 
ATOM 1210 S SD  . MET C 2 126 ? 137.305 125.077 117.349 1.00 84.06  ? 70  MET R SD  1 
ATOM 1211 C CE  . MET C 2 126 ? 136.106 124.193 116.361 1.00 84.06  ? 70  MET R CE  1 
ATOM 1212 N N   . LEU C 2 127 ? 137.900 129.893 120.529 1.00 83.08  ? 71  LEU R N   1 
ATOM 1213 C CA  . LEU C 2 127 ? 138.673 130.362 121.674 1.00 83.08  ? 71  LEU R CA  1 
ATOM 1214 C C   . LEU C 2 127 ? 137.776 131.052 122.695 1.00 83.08  ? 71  LEU R C   1 
ATOM 1215 O O   . LEU C 2 127 ? 137.913 130.840 123.905 1.00 83.08  ? 71  LEU R O   1 
ATOM 1216 C CB  . LEU C 2 127 ? 139.778 131.306 121.196 1.00 83.08  ? 71  LEU R CB  1 
ATOM 1217 C CG  . LEU C 2 127 ? 140.426 132.223 122.235 1.00 83.08  ? 71  LEU R CG  1 
ATOM 1218 C CD1 . LEU C 2 127 ? 141.037 131.414 123.366 1.00 83.08  ? 71  LEU R CD1 1 
ATOM 1219 C CD2 . LEU C 2 127 ? 141.478 133.098 121.576 1.00 83.08  ? 71  LEU R CD2 1 
ATOM 1220 N N   . VAL C 2 128 ? 136.846 131.883 122.223 1.00 82.37  ? 72  VAL R N   1 
ATOM 1221 C CA  . VAL C 2 128 ? 136.004 132.649 123.137 1.00 82.37  ? 72  VAL R CA  1 
ATOM 1222 C C   . VAL C 2 128 ? 135.127 131.721 123.967 1.00 82.37  ? 72  VAL R C   1 
ATOM 1223 O O   . VAL C 2 128 ? 135.049 131.850 125.195 1.00 82.37  ? 72  VAL R O   1 
ATOM 1224 C CB  . VAL C 2 128 ? 135.161 133.669 122.351 1.00 82.37  ? 72  VAL R CB  1 
ATOM 1225 C CG1 . VAL C 2 128 ? 134.001 134.173 123.198 1.00 82.37  ? 72  VAL R CG1 1 
ATOM 1226 C CG2 . VAL C 2 128 ? 136.029 134.826 121.889 1.00 82.37  ? 72  VAL R CG2 1 
ATOM 1227 N N   . ILE C 2 129 ? 134.452 130.774 123.315 1.00 82.45  ? 73  ILE R N   1 
ATOM 1228 C CA  . ILE C 2 129 ? 133.491 129.930 124.021 1.00 82.45  ? 73  ILE R CA  1 
ATOM 1229 C C   . ILE C 2 129 ? 134.206 129.001 124.994 1.00 82.45  ? 73  ILE R C   1 
ATOM 1230 O O   . ILE C 2 129 ? 133.819 128.881 126.162 1.00 82.45  ? 73  ILE R O   1 
ATOM 1231 C CB  . ILE C 2 129 ? 132.634 129.140 123.017 1.00 82.45  ? 73  ILE R CB  1 
ATOM 1232 C CG1 . ILE C 2 129 ? 131.788 130.097 122.175 1.00 82.45  ? 73  ILE R CG1 1 
ATOM 1233 C CG2 . ILE C 2 129 ? 131.746 128.143 123.752 1.00 82.45  ? 73  ILE R CG2 1 
ATOM 1234 C CD1 . ILE C 2 129 ? 131.034 129.423 121.049 1.00 82.45  ? 73  ILE R CD1 1 
ATOM 1235 N N   . LEU C 2 130 ? 135.261 128.331 124.531 1.00 81.94  ? 74  LEU R N   1 
ATOM 1236 C CA  . LEU C 2 130 ? 135.913 127.299 125.325 1.00 81.94  ? 74  LEU R CA  1 
ATOM 1237 C C   . LEU C 2 130 ? 136.754 127.854 126.467 1.00 81.94  ? 74  LEU R C   1 
ATOM 1238 O O   . LEU C 2 130 ? 137.044 127.111 127.412 1.00 81.94  ? 74  LEU R O   1 
ATOM 1239 C CB  . LEU C 2 130 ? 136.798 126.432 124.427 1.00 81.94  ? 74  LEU R CB  1 
ATOM 1240 C CG  . LEU C 2 130 ? 136.083 125.548 123.402 1.00 81.94  ? 74  LEU R CG  1 
ATOM 1241 C CD1 . LEU C 2 130 ? 137.092 124.696 122.653 1.00 81.94  ? 74  LEU R CD1 1 
ATOM 1242 C CD2 . LEU C 2 130 ? 135.032 124.672 124.064 1.00 81.94  ? 74  LEU R CD2 1 
ATOM 1243 N N   . TYR C 2 131 ? 137.156 129.125 126.411 1.00 90.36  ? 75  TYR R N   1 
ATOM 1244 C CA  . TYR C 2 131 ? 138.008 129.666 127.464 1.00 90.36  ? 75  TYR R CA  1 
ATOM 1245 C C   . TYR C 2 131 ? 137.290 129.671 128.807 1.00 90.36  ? 75  TYR R C   1 
ATOM 1246 O O   . TYR C 2 131 ? 137.880 129.314 129.833 1.00 90.36  ? 75  TYR R O   1 
ATOM 1247 C CB  . TYR C 2 131 ? 138.463 131.077 127.099 1.00 90.36  ? 75  TYR R CB  1 
ATOM 1248 C CG  . TYR C 2 131 ? 139.592 131.599 127.961 1.00 90.36  ? 75  TYR R CG  1 
ATOM 1249 C CD1 . TYR C 2 131 ? 139.366 132.000 129.271 1.00 90.36  ? 75  TYR R CD1 1 
ATOM 1250 C CD2 . TYR C 2 131 ? 140.884 131.694 127.462 1.00 90.36  ? 75  TYR R CD2 1 
ATOM 1251 C CE1 . TYR C 2 131 ? 140.393 132.478 130.060 1.00 90.36  ? 75  TYR R CE1 1 
ATOM 1252 C CE2 . TYR C 2 131 ? 141.918 132.171 128.244 1.00 90.36  ? 75  TYR R CE2 1 
ATOM 1253 C CZ  . TYR C 2 131 ? 141.667 132.562 129.541 1.00 90.36  ? 75  TYR R CZ  1 
ATOM 1254 O OH  . TYR C 2 131 ? 142.694 133.038 130.323 1.00 90.36  ? 75  TYR R OH  1 
ATOM 1255 N N   . SER C 2 132 ? 136.020 130.069 128.822 1.00 107.27 ? 76  SER R N   1 
ATOM 1256 C CA  . SER C 2 132 ? 135.220 130.131 130.038 1.00 107.27 ? 76  SER R CA  1 
ATOM 1257 C C   . SER C 2 132 ? 134.025 129.202 129.894 1.00 107.27 ? 76  SER R C   1 
ATOM 1258 O O   . SER C 2 132 ? 133.296 129.273 128.900 1.00 107.27 ? 76  SER R O   1 
ATOM 1259 C CB  . SER C 2 132 ? 134.749 131.560 130.316 1.00 107.27 ? 76  SER R CB  1 
ATOM 1260 O OG  . SER C 2 132 ? 134.182 132.142 129.156 1.00 107.27 ? 76  SER R OG  1 
ATOM 1261 N N   . ARG C 2 133 ? 133.826 128.338 130.887 1.00 109.68 ? 77  ARG R N   1 
ATOM 1262 C CA  . ARG C 2 133 ? 132.764 127.343 130.855 1.00 109.68 ? 77  ARG R CA  1 
ATOM 1263 C C   . ARG C 2 133 ? 131.510 127.786 131.597 1.00 109.68 ? 77  ARG R C   1 
ATOM 1264 O O   . ARG C 2 133 ? 130.565 126.999 131.712 1.00 109.68 ? 77  ARG R O   1 
ATOM 1265 C CB  . ARG C 2 133 ? 133.273 126.020 131.437 1.00 109.68 ? 77  ARG R CB  1 
ATOM 1266 C CG  . ARG C 2 133 ? 134.371 125.385 130.597 1.00 109.68 ? 77  ARG R CG  1 
ATOM 1267 C CD  . ARG C 2 133 ? 134.879 124.082 131.191 1.00 109.68 ? 77  ARG R CD  1 
ATOM 1268 N NE  . ARG C 2 133 ? 135.773 123.390 130.271 1.00 109.68 ? 77  ARG R NE  1 
ATOM 1269 C CZ  . ARG C 2 133 ? 136.372 122.235 130.527 1.00 109.68 ? 77  ARG R CZ  1 
ATOM 1270 N NH1 . ARG C 2 133 ? 136.197 121.605 131.678 1.00 109.68 ? 77  ARG R NH1 1 
ATOM 1271 N NH2 . ARG C 2 133 ? 137.166 121.698 129.606 1.00 109.68 ? 77  ARG R NH2 1 
ATOM 1272 N N   . VAL C 2 134 ? 131.475 129.017 132.098 1.00 118.51 ? 78  VAL R N   1 
ATOM 1273 C CA  . VAL C 2 134 ? 130.292 129.534 132.775 1.00 118.51 ? 78  VAL R CA  1 
ATOM 1274 C C   . VAL C 2 134 ? 129.354 130.155 131.750 1.00 118.51 ? 78  VAL R C   1 
ATOM 1275 O O   . VAL C 2 134 ? 129.784 130.795 130.784 1.00 118.51 ? 78  VAL R O   1 
ATOM 1276 C CB  . VAL C 2 134 ? 130.691 130.552 133.861 1.00 118.51 ? 78  VAL R CB  1 
ATOM 1277 C CG1 . VAL C 2 134 ? 129.455 131.094 134.564 1.00 118.51 ? 78  VAL R CG1 1 
ATOM 1278 C CG2 . VAL C 2 134 ? 131.645 129.916 134.861 1.00 118.51 ? 78  VAL R CG2 1 
ATOM 1279 N N   . GLY C 2 135 ? 128.054 129.966 131.963 1.00 108.23 ? 79  GLY R N   1 
ATOM 1280 C CA  . GLY C 2 135 ? 127.064 130.522 131.057 1.00 108.23 ? 79  GLY R CA  1 
ATOM 1281 C C   . GLY C 2 135 ? 127.108 129.937 129.664 1.00 108.23 ? 79  GLY R C   1 
ATOM 1282 O O   . GLY C 2 135 ? 126.919 130.667 128.685 1.00 108.23 ? 79  GLY R O   1 
ATOM 1283 N N   . ARG C 2 136 ? 127.354 128.634 129.546 1.00 95.63  ? 80  ARG R N   1 
ATOM 1284 C CA  . ARG C 2 136 ? 127.393 127.960 128.249 1.00 95.63  ? 80  ARG R CA  1 
ATOM 1285 C C   . ARG C 2 136 ? 125.962 127.651 127.830 1.00 95.63  ? 80  ARG R C   1 
ATOM 1286 O O   . ARG C 2 136 ? 125.474 126.529 127.976 1.00 95.63  ? 80  ARG R O   1 
ATOM 1287 C CB  . ARG C 2 136 ? 128.240 126.696 128.322 1.00 95.63  ? 80  ARG R CB  1 
ATOM 1288 C CG  . ARG C 2 136 ? 129.675 126.936 128.769 1.00 95.63  ? 80  ARG R CG  1 
ATOM 1289 C CD  . ARG C 2 136 ? 130.608 127.133 127.585 1.00 95.63  ? 80  ARG R CD  1 
ATOM 1290 N NE  . ARG C 2 136 ? 130.619 125.980 126.691 1.00 95.63  ? 80  ARG R NE  1 
ATOM 1291 C CZ  . ARG C 2 136 ? 131.555 125.041 126.677 1.00 95.63  ? 80  ARG R CZ  1 
ATOM 1292 N NH1 . ARG C 2 136 ? 132.579 125.067 127.516 1.00 95.63  ? 80  ARG R NH1 1 
ATOM 1293 N NH2 . ARG C 2 136 ? 131.461 124.046 125.800 1.00 95.63  ? 80  ARG R NH2 1 
ATOM 1294 N N   . SER C 2 137 ? 125.282 128.662 127.299 1.00 88.39  ? 81  SER R N   1 
ATOM 1295 C CA  . SER C 2 137 ? 123.890 128.530 126.907 1.00 88.39  ? 81  SER R CA  1 
ATOM 1296 C C   . SER C 2 137 ? 123.762 127.537 125.754 1.00 88.39  ? 81  SER R C   1 
ATOM 1297 O O   . SER C 2 137 ? 124.750 127.021 125.228 1.00 88.39  ? 81  SER R O   1 
ATOM 1298 C CB  . SER C 2 137 ? 123.314 129.892 126.526 1.00 88.39  ? 81  SER R CB  1 
ATOM 1299 O OG  . SER C 2 137 ? 124.246 130.645 125.771 1.00 88.39  ? 81  SER R OG  1 
ATOM 1300 N N   . VAL C 2 138 ? 122.518 127.260 125.358 1.00 81.94  ? 82  VAL R N   1 
ATOM 1301 C CA  . VAL C 2 138 ? 122.282 126.326 124.261 1.00 81.94  ? 82  VAL R CA  1 
ATOM 1302 C C   . VAL C 2 138 ? 122.910 126.848 122.976 1.00 81.94  ? 82  VAL R C   1 
ATOM 1303 O O   . VAL C 2 138 ? 123.532 126.092 122.220 1.00 81.94  ? 82  VAL R O   1 
ATOM 1304 C CB  . VAL C 2 138 ? 120.772 126.070 124.092 1.00 81.94  ? 82  VAL R CB  1 
ATOM 1305 C CG1 . VAL C 2 138 ? 120.207 125.395 125.332 1.00 81.94  ? 82  VAL R CG1 1 
ATOM 1306 C CG2 . VAL C 2 138 ? 120.028 127.365 123.791 1.00 81.94  ? 82  VAL R CG2 1 
ATOM 1307 N N   . THR C 2 139 ? 122.762 128.147 122.707 1.00 84.86  ? 83  THR R N   1 
ATOM 1308 C CA  . THR C 2 139 ? 123.313 128.713 121.481 1.00 84.86  ? 83  THR R CA  1 
ATOM 1309 C C   . THR C 2 139 ? 124.824 128.543 121.415 1.00 84.86  ? 83  THR R C   1 
ATOM 1310 O O   . THR C 2 139 ? 125.388 128.442 120.320 1.00 84.86  ? 83  THR R O   1 
ATOM 1311 C CB  . THR C 2 139 ? 122.944 130.193 121.372 1.00 84.86  ? 83  THR R CB  1 
ATOM 1312 O OG1 . THR C 2 139 ? 121.543 130.320 121.096 1.00 84.86  ? 83  THR R OG1 1 
ATOM 1313 C CG2 . THR C 2 139 ? 123.738 130.867 120.262 1.00 84.86  ? 83  THR R CG2 1 
ATOM 1314 N N   . ASP C 2 140 ? 125.496 128.508 122.567 1.00 88.69  ? 84  ASP R N   1 
ATOM 1315 C CA  . ASP C 2 140 ? 126.943 128.324 122.563 1.00 88.69  ? 84  ASP R CA  1 
ATOM 1316 C C   . ASP C 2 140 ? 127.331 126.979 121.966 1.00 88.69  ? 84  ASP R C   1 
ATOM 1317 O O   . ASP C 2 140 ? 128.357 126.879 121.284 1.00 88.69  ? 84  ASP R O   1 
ATOM 1318 C CB  . ASP C 2 140 ? 127.494 128.451 123.982 1.00 88.69  ? 84  ASP R CB  1 
ATOM 1319 C CG  . ASP C 2 140 ? 127.419 129.869 124.511 1.00 88.69  ? 84  ASP R CG  1 
ATOM 1320 O OD1 . ASP C 2 140 ? 126.990 130.766 123.756 1.00 88.69  ? 84  ASP R OD1 1 
ATOM 1321 O OD2 . ASP C 2 140 ? 127.790 130.088 125.684 1.00 88.69  ? 84  ASP R OD2 1 
ATOM 1322 N N   . VAL C 2 141 ? 126.533 125.939 122.210 1.00 81.94  ? 85  VAL R N   1 
ATOM 1323 C CA  . VAL C 2 141 ? 126.843 124.625 121.658 1.00 81.94  ? 85  VAL R CA  1 
ATOM 1324 C C   . VAL C 2 141 ? 126.661 124.624 120.146 1.00 81.94  ? 85  VAL R C   1 
ATOM 1325 O O   . VAL C 2 141 ? 127.481 124.063 119.411 1.00 81.94  ? 85  VAL R O   1 
ATOM 1326 C CB  . VAL C 2 141 ? 125.977 123.548 122.335 1.00 81.94  ? 85  VAL R CB  1 
ATOM 1327 C CG1 . VAL C 2 141 ? 126.019 122.254 121.541 1.00 81.94  ? 85  VAL R CG1 1 
ATOM 1328 C CG2 . VAL C 2 141 ? 126.447 123.316 123.760 1.00 81.94  ? 85  VAL R CG2 1 
ATOM 1329 N N   . TYR C 2 142 ? 125.586 125.244 119.655 1.00 81.94  ? 86  TYR R N   1 
ATOM 1330 C CA  . TYR C 2 142 ? 125.366 125.303 118.214 1.00 81.94  ? 86  TYR R CA  1 
ATOM 1331 C C   . TYR C 2 142 ? 126.506 126.036 117.520 1.00 81.94  ? 86  TYR R C   1 
ATOM 1332 O O   . TYR C 2 142 ? 127.013 125.587 116.486 1.00 81.94  ? 86  TYR R O   1 
ATOM 1333 C CB  . TYR C 2 142 ? 124.032 125.984 117.911 1.00 81.94  ? 86  TYR R CB  1 
ATOM 1334 C CG  . TYR C 2 142 ? 122.826 125.094 118.093 1.00 81.94  ? 86  TYR R CG  1 
ATOM 1335 C CD1 . TYR C 2 142 ? 122.693 123.915 117.375 1.00 81.94  ? 86  TYR R CD1 1 
ATOM 1336 C CD2 . TYR C 2 142 ? 121.816 125.438 118.979 1.00 81.94  ? 86  TYR R CD2 1 
ATOM 1337 C CE1 . TYR C 2 142 ? 121.592 123.102 117.539 1.00 81.94  ? 86  TYR R CE1 1 
ATOM 1338 C CE2 . TYR C 2 142 ? 120.712 124.632 119.148 1.00 81.94  ? 86  TYR R CE2 1 
ATOM 1339 C CZ  . TYR C 2 142 ? 120.604 123.465 118.426 1.00 81.94  ? 86  TYR R CZ  1 
ATOM 1340 O OH  . TYR C 2 142 ? 119.504 122.658 118.591 1.00 81.94  ? 86  TYR R OH  1 
ATOM 1341 N N   . LEU C 2 143 ? 126.926 127.172 118.079 1.00 81.94  ? 87  LEU R N   1 
ATOM 1342 C CA  . LEU C 2 143 ? 128.032 127.915 117.488 1.00 81.94  ? 87  LEU R CA  1 
ATOM 1343 C C   . LEU C 2 143 ? 129.319 127.103 117.525 1.00 81.94  ? 87  LEU R C   1 
ATOM 1344 O O   . LEU C 2 143 ? 130.104 127.125 116.570 1.00 81.94  ? 87  LEU R O   1 
ATOM 1345 C CB  . LEU C 2 143 ? 128.217 129.247 118.214 1.00 81.94  ? 87  LEU R CB  1 
ATOM 1346 C CG  . LEU C 2 143 ? 127.045 130.223 118.108 1.00 81.94  ? 87  LEU R CG  1 
ATOM 1347 C CD1 . LEU C 2 143 ? 127.245 131.400 119.048 1.00 81.94  ? 87  LEU R CD1 1 
ATOM 1348 C CD2 . LEU C 2 143 ? 126.870 130.701 116.676 1.00 81.94  ? 87  LEU R CD2 1 
ATOM 1349 N N   . LEU C 2 144 ? 129.555 126.380 118.621 1.00 81.94  ? 88  LEU R N   1 
ATOM 1350 C CA  . LEU C 2 144 ? 130.769 125.578 118.724 1.00 81.94  ? 88  LEU R CA  1 
ATOM 1351 C C   . LEU C 2 144 ? 130.842 124.546 117.606 1.00 81.94  ? 88  LEU R C   1 
ATOM 1352 O O   . LEU C 2 144 ? 131.887 124.387 116.965 1.00 81.94  ? 88  LEU R O   1 
ATOM 1353 C CB  . LEU C 2 144 ? 130.828 124.893 120.088 1.00 81.94  ? 88  LEU R CB  1 
ATOM 1354 C CG  . LEU C 2 144 ? 132.201 124.365 120.502 1.00 81.94  ? 88  LEU R CG  1 
ATOM 1355 C CD1 . LEU C 2 144 ? 133.055 125.482 121.073 1.00 81.94  ? 88  LEU R CD1 1 
ATOM 1356 C CD2 . LEU C 2 144 ? 132.052 123.235 121.506 1.00 81.94  ? 88  LEU R CD2 1 
ATOM 1357 N N   . ASN C 2 145 ? 129.742 123.833 117.357 1.00 81.94  ? 89  ASN R N   1 
ATOM 1358 C CA  . ASN C 2 145 ? 129.723 122.875 116.257 1.00 81.94  ? 89  ASN R CA  1 
ATOM 1359 C C   . ASN C 2 145 ? 129.848 123.577 114.912 1.00 81.94  ? 89  ASN R C   1 
ATOM 1360 O O   . ASN C 2 145 ? 130.561 123.101 114.021 1.00 81.94  ? 89  ASN R O   1 
ATOM 1361 C CB  . ASN C 2 145 ? 128.445 122.041 116.312 1.00 81.94  ? 89  ASN R CB  1 
ATOM 1362 C CG  . ASN C 2 145 ? 128.435 121.073 117.474 1.00 81.94  ? 89  ASN R CG  1 
ATOM 1363 O OD1 . ASN C 2 145 ? 129.032 120.000 117.407 1.00 81.94  ? 89  ASN R OD1 1 
ATOM 1364 N ND2 . ASN C 2 145 ? 127.768 121.454 118.554 1.00 81.94  ? 89  ASN R ND2 1 
ATOM 1365 N N   . LEU C 2 146 ? 129.164 124.711 114.745 1.00 81.94  ? 90  LEU R N   1 
ATOM 1366 C CA  . LEU C 2 146 ? 129.265 125.450 113.491 1.00 81.94  ? 90  LEU R CA  1 
ATOM 1367 C C   . LEU C 2 146 ? 130.695 125.907 113.240 1.00 81.94  ? 90  LEU R C   1 
ATOM 1368 O O   . LEU C 2 146 ? 131.177 125.856 112.103 1.00 81.94  ? 90  LEU R O   1 
ATOM 1369 C CB  . LEU C 2 146 ? 128.314 126.646 113.510 1.00 81.94  ? 90  LEU R CB  1 
ATOM 1370 C CG  . LEU C 2 146 ? 128.239 127.461 112.219 1.00 81.94  ? 90  LEU R CG  1 
ATOM 1371 C CD1 . LEU C 2 146 ? 127.596 126.651 111.108 1.00 81.94  ? 90  LEU R CD1 1 
ATOM 1372 C CD2 . LEU C 2 146 ? 127.472 128.750 112.455 1.00 81.94  ? 90  LEU R CD2 1 
ATOM 1373 N N   . ALA C 2 147 ? 131.388 126.359 114.286 1.00 81.94  ? 91  ALA R N   1 
ATOM 1374 C CA  . ALA C 2 147 ? 132.787 126.737 114.129 1.00 81.94  ? 91  ALA R CA  1 
ATOM 1375 C C   . ALA C 2 147 ? 133.634 125.542 113.711 1.00 81.94  ? 91  ALA R C   1 
ATOM 1376 O O   . ALA C 2 147 ? 134.496 125.660 112.833 1.00 81.94  ? 91  ALA R O   1 
ATOM 1377 C CB  . ALA C 2 147 ? 133.315 127.340 115.429 1.00 81.94  ? 91  ALA R CB  1 
ATOM 1378 N N   . LEU C 2 148 ? 133.405 124.382 114.330 1.00 81.94  ? 92  LEU R N   1 
ATOM 1379 C CA  . LEU C 2 148 ? 134.140 123.182 113.944 1.00 81.94  ? 92  LEU R CA  1 
ATOM 1380 C C   . LEU C 2 148 ? 133.802 122.773 112.516 1.00 81.94  ? 92  LEU R C   1 
ATOM 1381 O O   . LEU C 2 148 ? 134.686 122.396 111.739 1.00 81.94  ? 92  LEU R O   1 
ATOM 1382 C CB  . LEU C 2 148 ? 133.832 122.045 114.918 1.00 81.94  ? 92  LEU R CB  1 
ATOM 1383 C CG  . LEU C 2 148 ? 134.586 120.735 114.680 1.00 81.94  ? 92  LEU R CG  1 
ATOM 1384 C CD1 . LEU C 2 148 ? 136.065 120.907 114.973 1.00 81.94  ? 92  LEU R CD1 1 
ATOM 1385 C CD2 . LEU C 2 148 ? 133.999 119.623 115.530 1.00 81.94  ? 92  LEU R CD2 1 
ATOM 1386 N N   . ALA C 2 149 ? 132.520 122.840 112.152 1.00 81.94  ? 93  ALA R N   1 
ATOM 1387 C CA  . ALA C 2 149 ? 132.119 122.449 110.806 1.00 81.94  ? 93  ALA R CA  1 
ATOM 1388 C C   . ALA C 2 149 ? 132.766 123.344 109.757 1.00 81.94  ? 93  ALA R C   1 
ATOM 1389 O O   . ALA C 2 149 ? 133.236 122.859 108.722 1.00 81.94  ? 93  ALA R O   1 
ATOM 1390 C CB  . ALA C 2 149 ? 130.597 122.491 110.681 1.00 81.94  ? 93  ALA R CB  1 
ATOM 1391 N N   . ASP C 2 150 ? 132.799 124.654 110.006 1.00 82.01  ? 94  ASP R N   1 
ATOM 1392 C CA  . ASP C 2 150 ? 133.410 125.568 109.047 1.00 82.01  ? 94  ASP R CA  1 
ATOM 1393 C C   . ASP C 2 150 ? 134.929 125.465 109.076 1.00 82.01  ? 94  ASP R C   1 
ATOM 1394 O O   . ASP C 2 150 ? 135.586 125.612 108.040 1.00 82.01  ? 94  ASP R O   1 
ATOM 1395 C CB  . ASP C 2 150 ? 132.965 127.000 109.335 1.00 82.01  ? 94  ASP R CB  1 
ATOM 1396 C CG  . ASP C 2 150 ? 131.486 127.210 109.089 1.00 82.01  ? 94  ASP R CG  1 
ATOM 1397 O OD1 . ASP C 2 150 ? 130.836 126.288 108.553 1.00 82.01  ? 94  ASP R OD1 1 
ATOM 1398 O OD2 . ASP C 2 150 ? 130.971 128.294 109.433 1.00 82.01  ? 94  ASP R OD2 1 
ATOM 1399 N N   . LEU C 2 151 ? 135.505 125.216 110.254 1.00 81.94  ? 95  LEU R N   1 
ATOM 1400 C CA  . LEU C 2 151 ? 136.956 125.103 110.351 1.00 81.94  ? 95  LEU R CA  1 
ATOM 1401 C C   . LEU C 2 151 ? 137.472 123.928 109.530 1.00 81.94  ? 95  LEU R C   1 
ATOM 1402 O O   . LEU C 2 151 ? 138.448 124.063 108.784 1.00 81.94  ? 95  LEU R O   1 
ATOM 1403 C CB  . LEU C 2 151 ? 137.368 124.959 111.815 1.00 81.94  ? 95  LEU R CB  1 
ATOM 1404 C CG  . LEU C 2 151 ? 138.846 124.671 112.082 1.00 81.94  ? 95  LEU R CG  1 
ATOM 1405 C CD1 . LEU C 2 151 ? 139.701 125.859 111.678 1.00 81.94  ? 95  LEU R CD1 1 
ATOM 1406 C CD2 . LEU C 2 151 ? 139.058 124.327 113.545 1.00 81.94  ? 95  LEU R CD2 1 
ATOM 1407 N N   . LEU C 2 152 ? 136.830 122.765 109.654 1.00 81.94  ? 96  LEU R N   1 
ATOM 1408 C CA  . LEU C 2 152 ? 137.245 121.606 108.872 1.00 81.94  ? 96  LEU R CA  1 
ATOM 1409 C C   . LEU C 2 152 ? 137.053 121.856 107.382 1.00 81.94  ? 96  LEU R C   1 
ATOM 1410 O O   . LEU C 2 152 ? 137.908 121.494 106.565 1.00 81.94  ? 96  LEU R O   1 
ATOM 1411 C CB  . LEU C 2 152 ? 136.466 120.368 109.317 1.00 81.94  ? 96  LEU R CB  1 
ATOM 1412 C CG  . LEU C 2 152 ? 136.733 119.879 110.743 1.00 81.94  ? 96  LEU R CG  1 
ATOM 1413 C CD1 . LEU C 2 152 ? 135.849 118.688 111.073 1.00 81.94  ? 96  LEU R CD1 1 
ATOM 1414 C CD2 . LEU C 2 152 ? 138.199 119.525 110.934 1.00 81.94  ? 96  LEU R CD2 1 
ATOM 1415 N N   . PHE C 2 153 ? 135.932 122.477 107.008 1.00 81.94  ? 97  PHE R N   1 
ATOM 1416 C CA  . PHE C 2 153 ? 135.675 122.752 105.598 1.00 81.94  ? 97  PHE R CA  1 
ATOM 1417 C C   . PHE C 2 153 ? 136.771 123.625 105.002 1.00 81.94  ? 97  PHE R C   1 
ATOM 1418 O O   . PHE C 2 153 ? 137.258 123.356 103.898 1.00 81.94  ? 97  PHE R O   1 
ATOM 1419 C CB  . PHE C 2 153 ? 134.309 123.420 105.441 1.00 81.94  ? 97  PHE R CB  1 
ATOM 1420 C CG  . PHE C 2 153 ? 133.970 123.791 104.025 1.00 81.94  ? 97  PHE R CG  1 
ATOM 1421 C CD1 . PHE C 2 153 ? 133.309 122.897 103.203 1.00 81.94  ? 97  PHE R CD1 1 
ATOM 1422 C CD2 . PHE C 2 153 ? 134.300 125.037 103.521 1.00 81.94  ? 97  PHE R CD2 1 
ATOM 1423 C CE1 . PHE C 2 153 ? 132.992 123.234 101.903 1.00 81.94  ? 97  PHE R CE1 1 
ATOM 1424 C CE2 . PHE C 2 153 ? 133.985 125.379 102.222 1.00 81.94  ? 97  PHE R CE2 1 
ATOM 1425 C CZ  . PHE C 2 153 ? 133.329 124.476 101.413 1.00 81.94  ? 97  PHE R CZ  1 
ATOM 1426 N N   . ALA C 2 154 ? 137.174 124.676 105.719 1.00 81.94  ? 98  ALA R N   1 
ATOM 1427 C CA  . ALA C 2 154 ? 138.236 125.543 105.222 1.00 81.94  ? 98  ALA R CA  1 
ATOM 1428 C C   . ALA C 2 154 ? 139.571 124.810 105.174 1.00 81.94  ? 98  ALA R C   1 
ATOM 1429 O O   . ALA C 2 154 ? 140.429 125.126 104.342 1.00 81.94  ? 98  ALA R O   1 
ATOM 1430 C CB  . ALA C 2 154 ? 138.342 126.792 106.096 1.00 81.94  ? 98  ALA R CB  1 
ATOM 1431 N N   . LEU C 2 155 ? 139.765 123.831 106.060 1.00 81.94  ? 99  LEU R N   1 
ATOM 1432 C CA  . LEU C 2 155 ? 141.045 123.134 106.122 1.00 81.94  ? 99  LEU R CA  1 
ATOM 1433 C C   . LEU C 2 155 ? 141.360 122.412 104.818 1.00 81.94  ? 99  LEU R C   1 
ATOM 1434 O O   . LEU C 2 155 ? 142.534 122.201 104.495 1.00 81.94  ? 99  LEU R O   1 
ATOM 1435 C CB  . LEU C 2 155 ? 141.043 122.144 107.287 1.00 81.94  ? 99  LEU R CB  1 
ATOM 1436 C CG  . LEU C 2 155 ? 142.340 121.365 107.512 1.00 81.94  ? 99  LEU R CG  1 
ATOM 1437 C CD1 . LEU C 2 155 ? 143.459 122.300 107.942 1.00 81.94  ? 99  LEU R CD1 1 
ATOM 1438 C CD2 . LEU C 2 155 ? 142.124 120.270 108.543 1.00 81.94  ? 99  LEU R CD2 1 
ATOM 1439 N N   . THR C 2 156 ? 140.335 122.022 104.060 1.00 85.25  ? 100 THR R N   1 
ATOM 1440 C CA  . THR C 2 156 ? 140.545 121.329 102.796 1.00 85.25  ? 100 THR R CA  1 
ATOM 1441 C C   . THR C 2 156 ? 140.667 122.275 101.612 1.00 85.25  ? 100 THR R C   1 
ATOM 1442 O O   . THR C 2 156 ? 140.976 121.821 100.505 1.00 85.25  ? 100 THR R O   1 
ATOM 1443 C CB  . THR C 2 156 ? 139.396 120.352 102.528 1.00 85.25  ? 100 THR R CB  1 
ATOM 1444 O OG1 . THR C 2 156 ? 138.143 121.035 102.658 1.00 85.25  ? 100 THR R OG1 1 
ATOM 1445 C CG2 . THR C 2 156 ? 139.445 119.191 103.506 1.00 85.25  ? 100 THR R CG2 1 
ATOM 1446 N N   . LEU C 2 157 ? 140.431 123.570 101.813 1.00 81.94  ? 101 LEU R N   1 
ATOM 1447 C CA  . LEU C 2 157 ? 140.480 124.507 100.696 1.00 81.94  ? 101 LEU R CA  1 
ATOM 1448 C C   . LEU C 2 157 ? 141.836 124.535 100.002 1.00 81.94  ? 101 LEU R C   1 
ATOM 1449 O O   . LEU C 2 157 ? 141.859 124.545 98.759  1.00 81.94  ? 101 LEU R O   1 
ATOM 1450 C CB  . LEU C 2 157 ? 140.096 125.909 101.186 1.00 81.94  ? 101 LEU R CB  1 
ATOM 1451 C CG  . LEU C 2 157 ? 138.595 126.191 101.301 1.00 81.94  ? 101 LEU R CG  1 
ATOM 1452 C CD1 . LEU C 2 157 ? 138.361 127.555 101.927 1.00 81.94  ? 101 LEU R CD1 1 
ATOM 1453 C CD2 . LEU C 2 157 ? 137.907 126.100 99.948  1.00 81.94  ? 101 LEU R CD2 1 
ATOM 1454 N N   . PRO C 2 158 ? 142.971 124.555 100.705 1.00 81.94  ? 102 PRO R N   1 
ATOM 1455 C CA  . PRO C 2 158 ? 144.261 124.625 99.995  1.00 81.94  ? 102 PRO R CA  1 
ATOM 1456 C C   . PRO C 2 158 ? 144.461 123.509 98.984  1.00 81.94  ? 102 PRO R C   1 
ATOM 1457 O O   . PRO C 2 158 ? 145.005 123.755 97.901  1.00 81.94  ? 102 PRO R O   1 
ATOM 1458 C CB  . PRO C 2 158 ? 145.285 124.552 101.136 1.00 81.94  ? 102 PRO R CB  1 
ATOM 1459 C CG  . PRO C 2 158 ? 144.558 125.052 102.330 1.00 81.94  ? 102 PRO R CG  1 
ATOM 1460 C CD  . PRO C 2 158 ? 143.145 124.588 102.166 1.00 81.94  ? 102 PRO R CD  1 
ATOM 1461 N N   . ILE C 2 159 ? 144.039 122.285 99.304  1.00 81.94  ? 103 ILE R N   1 
ATOM 1462 C CA  . ILE C 2 159 ? 144.150 121.197 98.339  1.00 81.94  ? 103 ILE R CA  1 
ATOM 1463 C C   . ILE C 2 159 ? 143.182 121.415 97.183  1.00 81.94  ? 103 ILE R C   1 
ATOM 1464 O O   . ILE C 2 159 ? 143.539 121.232 96.014  1.00 81.94  ? 103 ILE R O   1 
ATOM 1465 C CB  . ILE C 2 159 ? 143.918 119.841 99.030  1.00 81.94  ? 103 ILE R CB  1 
ATOM 1466 C CG1 . ILE C 2 159 ? 145.116 119.500 99.920  1.00 81.94  ? 103 ILE R CG1 1 
ATOM 1467 C CG2 . ILE C 2 159 ? 143.684 118.751 97.990  1.00 81.94  ? 103 ILE R CG2 1 
ATOM 1468 C CD1 . ILE C 2 159 ? 144.940 118.244 100.752 1.00 81.94  ? 103 ILE R CD1 1 
ATOM 1469 N N   . TRP C 2 160 ? 141.944 121.808 97.489  1.00 84.86  ? 104 TRP R N   1 
ATOM 1470 C CA  . TRP C 2 160 ? 140.971 122.060 96.432  1.00 84.86  ? 104 TRP R CA  1 
ATOM 1471 C C   . TRP C 2 160 ? 141.417 123.199 95.527  1.00 84.86  ? 104 TRP R C   1 
ATOM 1472 O O   . TRP C 2 160 ? 141.235 123.129 94.306  1.00 84.86  ? 104 TRP R O   1 
ATOM 1473 C CB  . TRP C 2 160 ? 139.606 122.374 97.043  1.00 84.86  ? 104 TRP R CB  1 
ATOM 1474 C CG  . TRP C 2 160 ? 138.456 121.889 96.221  1.00 84.86  ? 104 TRP R CG  1 
ATOM 1475 C CD1 . TRP C 2 160 ? 137.581 122.650 95.503  1.00 84.86  ? 104 TRP R CD1 1 
ATOM 1476 C CD2 . TRP C 2 160 ? 138.051 120.528 96.034  1.00 84.86  ? 104 TRP R CD2 1 
ATOM 1477 N NE1 . TRP C 2 160 ? 136.658 121.848 94.879  1.00 84.86  ? 104 TRP R NE1 1 
ATOM 1478 C CE2 . TRP C 2 160 ? 136.924 120.540 95.190  1.00 84.86  ? 104 TRP R CE2 1 
ATOM 1479 C CE3 . TRP C 2 160 ? 138.532 119.301 96.499  1.00 84.86  ? 104 TRP R CE3 1 
ATOM 1480 C CZ2 . TRP C 2 160 ? 136.271 119.374 94.800  1.00 84.86  ? 104 TRP R CZ2 1 
ATOM 1481 C CZ3 . TRP C 2 160 ? 137.884 118.145 96.111  1.00 84.86  ? 104 TRP R CZ3 1 
ATOM 1482 C CH2 . TRP C 2 160 ? 136.765 118.189 95.270  1.00 84.86  ? 104 TRP R CH2 1 
ATOM 1483 N N   . ALA C 2 161 ? 141.997 124.255 96.101  1.00 81.94  ? 105 ALA R N   1 
ATOM 1484 C CA  . ALA C 2 161 ? 142.458 125.377 95.290  1.00 81.94  ? 105 ALA R CA  1 
ATOM 1485 C C   . ALA C 2 161 ? 143.546 124.939 94.318  1.00 81.94  ? 105 ALA R C   1 
ATOM 1486 O O   . ALA C 2 161 ? 143.507 125.282 93.131  1.00 81.94  ? 105 ALA R O   1 
ATOM 1487 C CB  . ALA C 2 161 ? 142.965 126.500 96.195  1.00 81.94  ? 105 ALA R CB  1 
ATOM 1488 N N   . ALA C 2 162 ? 144.527 124.176 94.805  1.00 81.94  ? 106 ALA R N   1 
ATOM 1489 C CA  . ALA C 2 162 ? 145.597 123.708 93.931  1.00 81.94  ? 106 ALA R CA  1 
ATOM 1490 C C   . ALA C 2 162 ? 145.064 122.807 92.826  1.00 81.94  ? 106 ALA R C   1 
ATOM 1491 O O   . ALA C 2 162 ? 145.653 122.744 91.741  1.00 81.94  ? 106 ALA R O   1 
ATOM 1492 C CB  . ALA C 2 162 ? 146.658 122.972 94.747  1.00 81.94  ? 106 ALA R CB  1 
ATOM 1493 N N   . SER C 2 163 ? 143.960 122.103 93.080  1.00 85.24  ? 107 SER R N   1 
ATOM 1494 C CA  . SER C 2 163 ? 143.378 121.247 92.051  1.00 85.24  ? 107 SER R CA  1 
ATOM 1495 C C   . SER C 2 163 ? 142.914 122.065 90.853  1.00 85.24  ? 107 SER R C   1 
ATOM 1496 O O   . SER C 2 163 ? 143.090 121.647 89.703  1.00 85.24  ? 107 SER R O   1 
ATOM 1497 C CB  . SER C 2 163 ? 142.215 120.447 92.634  1.00 85.24  ? 107 SER R CB  1 
ATOM 1498 O OG  . SER C 2 163 ? 141.492 119.784 91.613  1.00 85.24  ? 107 SER R OG  1 
ATOM 1499 N N   . LYS C 2 164 ? 142.320 123.233 91.101  1.00 90.27  ? 108 LYS R N   1 
ATOM 1500 C CA  . LYS C 2 164 ? 141.813 124.054 90.007  1.00 90.27  ? 108 LYS R CA  1 
ATOM 1501 C C   . LYS C 2 164 ? 142.937 124.557 89.110  1.00 90.27  ? 108 LYS R C   1 
ATOM 1502 O O   . LYS C 2 164 ? 142.680 124.992 87.982  1.00 90.27  ? 108 LYS R O   1 
ATOM 1503 C CB  . LYS C 2 164 ? 141.022 125.236 90.568  1.00 90.27  ? 108 LYS R CB  1 
ATOM 1504 C CG  . LYS C 2 164 ? 139.809 124.835 91.391  1.00 90.27  ? 108 LYS R CG  1 
ATOM 1505 C CD  . LYS C 2 164 ? 138.512 125.285 90.742  1.00 90.27  ? 108 LYS R CD  1 
ATOM 1506 C CE  . LYS C 2 164 ? 137.321 124.546 91.326  1.00 90.27  ? 108 LYS R CE  1 
ATOM 1507 N NZ  . LYS C 2 164 ? 136.029 125.050 90.786  1.00 90.27  ? 108 LYS R NZ  1 
ATOM 1508 N N   . VAL C 2 165 ? 144.181 124.510 89.585  1.00 92.26  ? 109 VAL R N   1 
ATOM 1509 C CA  . VAL C 2 165 ? 145.298 125.039 88.808  1.00 92.26  ? 109 VAL R CA  1 
ATOM 1510 C C   . VAL C 2 165 ? 145.654 124.097 87.666  1.00 92.26  ? 109 VAL R C   1 
ATOM 1511 O O   . VAL C 2 165 ? 145.571 124.463 86.488  1.00 92.26  ? 109 VAL R O   1 
ATOM 1512 C CB  . VAL C 2 165 ? 146.513 125.291 89.719  1.00 92.26  ? 109 VAL R CB  1 
ATOM 1513 C CG1 . VAL C 2 165 ? 147.782 125.439 88.889  1.00 92.26  ? 109 VAL R CG1 1 
ATOM 1514 C CG2 . VAL C 2 165 ? 146.286 126.521 90.574  1.00 92.26  ? 109 VAL R CG2 1 
ATOM 1515 N N   . ASN C 2 166 ? 146.060 122.871 87.998  1.00 87.72  ? 110 ASN R N   1 
ATOM 1516 C CA  . ASN C 2 166 ? 146.513 121.906 87.003  1.00 87.72  ? 110 ASN R CA  1 
ATOM 1517 C C   . ASN C 2 166 ? 145.798 120.566 87.115  1.00 87.72  ? 110 ASN R C   1 
ATOM 1518 O O   . ASN C 2 166 ? 146.334 119.551 86.655  1.00 87.72  ? 110 ASN R O   1 
ATOM 1519 C CB  . ASN C 2 166 ? 148.026 121.698 87.124  1.00 87.72  ? 110 ASN R CB  1 
ATOM 1520 C CG  . ASN C 2 166 ? 148.667 121.302 85.809  1.00 87.72  ? 110 ASN R CG  1 
ATOM 1521 O OD1 . ASN C 2 166 ? 148.253 121.755 84.742  1.00 87.72  ? 110 ASN R OD1 1 
ATOM 1522 N ND2 . ASN C 2 166 ? 149.683 120.451 85.879  1.00 87.72  ? 110 ASN R ND2 1 
ATOM 1523 N N   . GLY C 2 167 ? 144.613 120.530 87.712  1.00 81.94  ? 111 GLY R N   1 
ATOM 1524 C CA  . GLY C 2 167 ? 143.854 119.305 87.850  1.00 81.94  ? 111 GLY R CA  1 
ATOM 1525 C C   . GLY C 2 167 ? 144.305 118.482 89.044  1.00 81.94  ? 111 GLY R C   1 
ATOM 1526 O O   . GLY C 2 167 ? 145.296 118.777 89.717  1.00 81.94  ? 111 GLY R O   1 
ATOM 1527 N N   . TRP C 2 168 ? 143.546 117.419 89.303  1.00 69.13  ? 112 TRP R N   1 
ATOM 1528 C CA  . TRP C 2 168 ? 143.834 116.537 90.426  1.00 69.13  ? 112 TRP R CA  1 
ATOM 1529 C C   . TRP C 2 168 ? 145.053 115.670 90.142  1.00 69.13  ? 112 TRP R C   1 
ATOM 1530 O O   . TRP C 2 168 ? 144.954 114.657 89.443  1.00 69.13  ? 112 TRP R O   1 
ATOM 1531 C CB  . TRP C 2 168 ? 142.624 115.658 90.739  1.00 69.13  ? 112 TRP R CB  1 
ATOM 1532 C CG  . TRP C 2 168 ? 142.666 115.078 92.112  1.00 69.13  ? 112 TRP R CG  1 
ATOM 1533 C CD1 . TRP C 2 168 ? 143.081 113.828 92.461  1.00 69.13  ? 112 TRP R CD1 1 
ATOM 1534 C CD2 . TRP C 2 168 ? 142.285 115.728 93.329  1.00 69.13  ? 112 TRP R CD2 1 
ATOM 1535 N NE1 . TRP C 2 168 ? 142.980 113.658 93.820  1.00 69.13  ? 112 TRP R NE1 1 
ATOM 1536 C CE2 . TRP C 2 168 ? 142.493 114.812 94.375  1.00 69.13  ? 112 TRP R CE2 1 
ATOM 1537 C CE3 . TRP C 2 168 ? 141.786 116.998 93.633  1.00 69.13  ? 112 TRP R CE3 1 
ATOM 1538 C CZ2 . TRP C 2 168 ? 142.220 115.123 95.703  1.00 69.13  ? 112 TRP R CZ2 1 
ATOM 1539 C CZ3 . TRP C 2 168 ? 141.515 117.305 94.952  1.00 69.13  ? 112 TRP R CZ3 1 
ATOM 1540 C CH2 . TRP C 2 168 ? 141.732 116.372 95.971  1.00 69.13  ? 112 TRP R CH2 1 
ATOM 1541 N N   . ILE C 2 169 ? 146.207 116.060 90.684  1.00 81.94  ? 113 ILE R N   1 
ATOM 1542 C CA  . ILE C 2 169 ? 147.442 115.300 90.532  1.00 81.94  ? 113 ILE R CA  1 
ATOM 1543 C C   . ILE C 2 169 ? 147.783 114.520 91.798  1.00 81.94  ? 113 ILE R C   1 
ATOM 1544 O O   . ILE C 2 169 ? 148.848 113.902 91.875  1.00 81.94  ? 113 ILE R O   1 
ATOM 1545 C CB  . ILE C 2 169 ? 148.604 116.227 90.137  1.00 81.94  ? 113 ILE R CB  1 
ATOM 1546 C CG1 . ILE C 2 169 ? 148.193 117.140 88.979  1.00 81.94  ? 113 ILE R CG1 1 
ATOM 1547 C CG2 . ILE C 2 169 ? 149.832 115.419 89.742  1.00 81.94  ? 113 ILE R CG2 1 
ATOM 1548 C CD1 . ILE C 2 169 ? 147.667 116.400 87.766  1.00 81.94  ? 113 ILE R CD1 1 
ATOM 1549 N N   . PHE C 2 170 ? 146.894 114.522 92.789  1.00 81.94  ? 114 PHE R N   1 
ATOM 1550 C CA  . PHE C 2 170 ? 147.219 114.028 94.119  1.00 81.94  ? 114 PHE R CA  1 
ATOM 1551 C C   . PHE C 2 170 ? 146.879 112.558 94.329  1.00 81.94  ? 114 PHE R C   1 
ATOM 1552 O O   . PHE C 2 170 ? 147.151 112.029 95.411  1.00 81.94  ? 114 PHE R O   1 
ATOM 1553 C CB  . PHE C 2 170 ? 146.494 114.874 95.169  1.00 81.94  ? 114 PHE R CB  1 
ATOM 1554 C CG  . PHE C 2 170 ? 146.802 116.338 95.074  1.00 81.94  ? 114 PHE R CG  1 
ATOM 1555 C CD1 . PHE C 2 170 ? 148.013 116.832 95.525  1.00 81.94  ? 114 PHE R CD1 1 
ATOM 1556 C CD2 . PHE C 2 170 ? 145.887 117.219 94.527  1.00 81.94  ? 114 PHE R CD2 1 
ATOM 1557 C CE1 . PHE C 2 170 ? 148.303 118.177 95.435  1.00 81.94  ? 114 PHE R CE1 1 
ATOM 1558 C CE2 . PHE C 2 170 ? 146.172 118.565 94.436  1.00 81.94  ? 114 PHE R CE2 1 
ATOM 1559 C CZ  . PHE C 2 170 ? 147.381 119.045 94.891  1.00 81.94  ? 114 PHE R CZ  1 
ATOM 1560 N N   . GLY C 2 171 ? 146.303 111.890 93.342  1.00 81.94  ? 115 GLY R N   1 
ATOM 1561 C CA  . GLY C 2 171 ? 146.006 110.475 93.436  1.00 81.94  ? 115 GLY R CA  1 
ATOM 1562 C C   . GLY C 2 171 ? 144.556 110.217 93.814  1.00 81.94  ? 115 GLY R C   1 
ATOM 1563 O O   . GLY C 2 171 ? 143.783 111.122 94.126  1.00 81.94  ? 115 GLY R O   1 
ATOM 1564 N N   . THR C 2 172 ? 144.203 108.930 93.776  1.00 81.94  ? 116 THR R N   1 
ATOM 1565 C CA  . THR C 2 172 ? 142.824 108.518 94.021  1.00 81.94  ? 116 THR R CA  1 
ATOM 1566 C C   . THR C 2 172 ? 142.469 108.550 95.502  1.00 81.94  ? 116 THR R C   1 
ATOM 1567 O O   . THR C 2 172 ? 141.336 108.888 95.860  1.00 81.94  ? 116 THR R O   1 
ATOM 1568 C CB  . THR C 2 172 ? 142.592 107.114 93.460  1.00 81.94  ? 116 THR R CB  1 
ATOM 1569 O OG1 . THR C 2 172 ? 142.745 107.134 92.036  1.00 81.94  ? 116 THR R OG1 1 
ATOM 1570 C CG2 . THR C 2 172 ? 141.196 106.620 93.810  1.00 81.94  ? 116 THR R CG2 1 
ATOM 1571 N N   . PHE C 2 173 ? 143.414 108.199 96.375  1.00 81.94  ? 117 PHE R N   1 
ATOM 1572 C CA  . PHE C 2 173 ? 143.093 108.069 97.793  1.00 81.94  ? 117 PHE R CA  1 
ATOM 1573 C C   . PHE C 2 173 ? 142.600 109.390 98.369  1.00 81.94  ? 117 PHE R C   1 
ATOM 1574 O O   . PHE C 2 173 ? 141.616 109.426 99.117  1.00 81.94  ? 117 PHE R O   1 
ATOM 1575 C CB  . PHE C 2 173 ? 144.316 107.571 98.563  1.00 81.94  ? 117 PHE R CB  1 
ATOM 1576 C CG  . PHE C 2 173 ? 144.086 107.437 100.039 1.00 81.94  ? 117 PHE R CG  1 
ATOM 1577 C CD1 . PHE C 2 173 ? 143.314 106.404 100.539 1.00 81.94  ? 117 PHE R CD1 1 
ATOM 1578 C CD2 . PHE C 2 173 ? 144.639 108.343 100.926 1.00 81.94  ? 117 PHE R CD2 1 
ATOM 1579 C CE1 . PHE C 2 173 ? 143.099 106.276 101.896 1.00 81.94  ? 117 PHE R CE1 1 
ATOM 1580 C CE2 . PHE C 2 173 ? 144.428 108.220 102.284 1.00 81.94  ? 117 PHE R CE2 1 
ATOM 1581 C CZ  . PHE C 2 173 ? 143.657 107.185 102.770 1.00 81.94  ? 117 PHE R CZ  1 
ATOM 1582 N N   . LEU C 2 174 ? 143.272 110.491 98.030  1.00 81.94  ? 118 LEU R N   1 
ATOM 1583 C CA  . LEU C 2 174 ? 142.858 111.790 98.547  1.00 81.94  ? 118 LEU R CA  1 
ATOM 1584 C C   . LEU C 2 174 ? 141.564 112.269 97.901  1.00 81.94  ? 118 LEU R C   1 
ATOM 1585 O O   . LEU C 2 174 ? 140.789 112.990 98.538  1.00 81.94  ? 118 LEU R O   1 
ATOM 1586 C CB  . LEU C 2 174 ? 143.972 112.814 98.339  1.00 81.94  ? 118 LEU R CB  1 
ATOM 1587 C CG  . LEU C 2 174 ? 145.288 112.471 99.040  1.00 81.94  ? 118 LEU R CG  1 
ATOM 1588 C CD1 . LEU C 2 174 ? 146.417 113.346 98.528  1.00 81.94  ? 118 LEU R CD1 1 
ATOM 1589 C CD2 . LEU C 2 174 ? 145.144 112.605 100.547 1.00 81.94  ? 118 LEU R CD2 1 
ATOM 1590 N N   . CYS C 2 175 ? 141.312 111.885 96.648  1.00 81.94  ? 119 CYS R N   1 
ATOM 1591 C CA  . CYS C 2 175 ? 140.066 112.278 95.997  1.00 81.94  ? 119 CYS R CA  1 
ATOM 1592 C C   . CYS C 2 175 ? 138.862 111.731 96.753  1.00 81.94  ? 119 CYS R C   1 
ATOM 1593 O O   . CYS C 2 175 ? 137.756 112.275 96.653  1.00 81.94  ? 119 CYS R O   1 
ATOM 1594 C CB  . CYS C 2 175 ? 140.064 111.801 94.543  1.00 81.74  ? 119 CYS R CB  1 
ATOM 1595 S SG  . CYS C 2 175 ? 138.436 111.703 93.743  1.00 81.74  ? 119 CYS R SG  1 
ATOM 1596 N N   . LYS C 2 176 ? 139.058 110.655 97.518  1.00 81.94  ? 120 LYS R N   1 
ATOM 1597 C CA  . LYS C 2 176 ? 137.982 110.130 98.354  1.00 81.94  ? 120 LYS R CA  1 
ATOM 1598 C C   . LYS C 2 176 ? 137.983 110.792 99.727  1.00 81.94  ? 120 LYS R C   1 
ATOM 1599 O O   . LYS C 2 176 ? 136.947 111.280 100.193 1.00 81.94  ? 120 LYS R O   1 
ATOM 1600 C CB  . LYS C 2 176 ? 138.120 108.614 98.494  1.00 65.83  ? 120 LYS R CB  1 
ATOM 1601 C CG  . LYS C 2 176 ? 137.831 107.840 97.221  1.00 65.83  ? 120 LYS R CG  1 
ATOM 1602 C CD  . LYS C 2 176 ? 138.008 106.348 97.440  1.00 65.83  ? 120 LYS R CD  1 
ATOM 1603 C CE  . LYS C 2 176 ? 137.539 105.547 96.240  1.00 65.83  ? 120 LYS R CE  1 
ATOM 1604 N NZ  . LYS C 2 176 ? 136.055 105.487 96.155  1.00 65.83  ? 120 LYS R NZ  1 
ATOM 1605 N N   . VAL C 2 177 ? 139.140 110.817 100.392 1.00 81.94  ? 121 VAL R N   1 
ATOM 1606 C CA  . VAL C 2 177 ? 139.211 111.367 101.743 1.00 81.94  ? 121 VAL R CA  1 
ATOM 1607 C C   . VAL C 2 177 ? 138.856 112.849 101.733 1.00 81.94  ? 121 VAL R C   1 
ATOM 1608 O O   . VAL C 2 177 ? 138.030 113.313 102.527 1.00 81.94  ? 121 VAL R O   1 
ATOM 1609 C CB  . VAL C 2 177 ? 140.607 111.128 102.345 1.00 81.94  ? 121 VAL R CB  1 
ATOM 1610 C CG1 . VAL C 2 177 ? 140.798 111.965 103.601 1.00 81.94  ? 121 VAL R CG1 1 
ATOM 1611 C CG2 . VAL C 2 177 ? 140.809 109.653 102.646 1.00 81.94  ? 121 VAL R CG2 1 
ATOM 1612 N N   . VAL C 2 178 ? 139.478 113.614 100.835 1.00 81.94  ? 122 VAL R N   1 
ATOM 1613 C CA  . VAL C 2 178 ? 139.223 115.050 100.789 1.00 81.94  ? 122 VAL R CA  1 
ATOM 1614 C C   . VAL C 2 178 ? 137.766 115.321 100.440 1.00 81.94  ? 122 VAL R C   1 
ATOM 1615 O O   . VAL C 2 178 ? 137.124 116.193 101.037 1.00 81.94  ? 122 VAL R O   1 
ATOM 1616 C CB  . VAL C 2 178 ? 140.180 115.732 99.795  1.00 81.94  ? 122 VAL R CB  1 
ATOM 1617 C CG1 . VAL C 2 178 ? 139.813 117.199 99.631  1.00 81.94  ? 122 VAL R CG1 1 
ATOM 1618 C CG2 . VAL C 2 178 ? 141.618 115.587 100.262 1.00 81.94  ? 122 VAL R CG2 1 
ATOM 1619 N N   . SER C 2 179 ? 137.221 114.587 99.468  1.00 81.94  ? 123 SER R N   1 
ATOM 1620 C CA  . SER C 2 179 ? 135.823 114.784 99.098  1.00 81.94  ? 123 SER R CA  1 
ATOM 1621 C C   . SER C 2 179 ? 134.897 114.427 100.253 1.00 81.94  ? 123 SER R C   1 
ATOM 1622 O O   . SER C 2 179 ? 133.850 115.059 100.437 1.00 81.94  ? 123 SER R O   1 
ATOM 1623 C CB  . SER C 2 179 ? 135.485 113.953 97.862  1.00 81.94  ? 123 SER R CB  1 
ATOM 1624 O OG  . SER C 2 179 ? 136.317 114.303 96.770  1.00 81.94  ? 123 SER R OG  1 
ATOM 1625 N N   . LEU C 2 180 ? 135.261 113.413 101.039 1.00 81.94  ? 124 LEU R N   1 
ATOM 1626 C CA  . LEU C 2 180 ? 134.465 113.062 102.210 1.00 81.94  ? 124 LEU R CA  1 
ATOM 1627 C C   . LEU C 2 180 ? 134.462 114.197 103.226 1.00 81.94  ? 124 LEU R C   1 
ATOM 1628 O O   . LEU C 2 180 ? 133.404 114.608 103.715 1.00 81.94  ? 124 LEU R O   1 
ATOM 1629 C CB  . LEU C 2 180 ? 135.003 111.779 102.843 1.00 81.94  ? 124 LEU R CB  1 
ATOM 1630 C CG  . LEU C 2 180 ? 134.286 111.306 104.110 1.00 81.94  ? 124 LEU R CG  1 
ATOM 1631 C CD1 . LEU C 2 180 ? 132.840 110.953 103.809 1.00 81.94  ? 124 LEU R CD1 1 
ATOM 1632 C CD2 . LEU C 2 180 ? 135.010 110.123 104.730 1.00 81.94  ? 124 LEU R CD2 1 
ATOM 1633 N N   . LEU C 2 181 ? 135.644 114.719 103.556 1.00 81.94  ? 125 LEU R N   1 
ATOM 1634 C CA  . LEU C 2 181 ? 135.734 115.762 104.571 1.00 81.94  ? 125 LEU R CA  1 
ATOM 1635 C C   . LEU C 2 181 ? 134.995 117.019 104.130 1.00 81.94  ? 125 LEU R C   1 
ATOM 1636 O O   . LEU C 2 181 ? 134.300 117.658 104.928 1.00 81.94  ? 125 LEU R O   1 
ATOM 1637 C CB  . LEU C 2 181 ? 137.200 116.073 104.869 1.00 81.94  ? 125 LEU R CB  1 
ATOM 1638 C CG  . LEU C 2 181 ? 137.508 116.458 106.317 1.00 81.94  ? 125 LEU R CG  1 
ATOM 1639 C CD1 . LEU C 2 181 ? 137.559 115.220 107.196 1.00 81.94  ? 125 LEU R CD1 1 
ATOM 1640 C CD2 . LEU C 2 181 ? 138.811 117.230 106.402 1.00 81.94  ? 125 LEU R CD2 1 
ATOM 1641 N N   . LYS C 2 182 ? 135.135 117.393 102.857 1.00 81.94  ? 126 LYS R N   1 
ATOM 1642 C CA  . LYS C 2 182 ? 134.488 118.606 102.369 1.00 81.94  ? 126 LYS R CA  1 
ATOM 1643 C C   . LYS C 2 182 ? 132.971 118.481 102.420 1.00 81.94  ? 126 LYS R C   1 
ATOM 1644 O O   . LYS C 2 182 ? 132.279 119.377 102.917 1.00 81.94  ? 126 LYS R O   1 
ATOM 1645 C CB  . LYS C 2 182 ? 134.949 118.909 100.943 1.00 81.94  ? 126 LYS R CB  1 
ATOM 1646 C CG  . LYS C 2 182 ? 134.320 120.161 100.346 1.00 81.94  ? 126 LYS R CG  1 
ATOM 1647 C CD  . LYS C 2 182 ? 134.727 120.359 98.898  1.00 81.94  ? 126 LYS R CD  1 
ATOM 1648 C CE  . LYS C 2 182 ? 134.041 121.575 98.300  1.00 81.94  ? 126 LYS R CE  1 
ATOM 1649 N NZ  . LYS C 2 182 ? 134.690 122.019 97.039  1.00 81.94  ? 126 LYS R NZ  1 
ATOM 1650 N N   . GLU C 2 183 ? 132.431 117.373 101.908 1.00 81.94  ? 127 GLU R N   1 
ATOM 1651 C CA  . GLU C 2 183 ? 130.981 117.249 101.811 1.00 81.94  ? 127 GLU R CA  1 
ATOM 1652 C C   . GLU C 2 183 ? 130.353 116.991 103.174 1.00 81.94  ? 127 GLU R C   1 
ATOM 1653 O O   . GLU C 2 183 ? 129.234 117.442 103.442 1.00 81.94  ? 127 GLU R O   1 
ATOM 1654 C CB  . GLU C 2 183 ? 130.608 116.135 100.835 1.00 81.94  ? 127 GLU R CB  1 
ATOM 1655 C CG  . GLU C 2 183 ? 129.317 116.407 100.080 1.00 81.94  ? 127 GLU R CG  1 
ATOM 1656 C CD  . GLU C 2 183 ? 128.752 115.172 99.410  1.00 81.94  ? 127 GLU R CD  1 
ATOM 1657 O OE1 . GLU C 2 183 ? 129.123 114.050 99.813  1.00 81.94  ? 127 GLU R OE1 1 
ATOM 1658 O OE2 . GLU C 2 183 ? 127.935 115.325 98.478  1.00 81.94  ? 127 GLU R OE2 1 
ATOM 1659 N N   . VAL C 2 184 ? 131.053 116.266 104.048 1.00 81.94  ? 128 VAL R N   1 
ATOM 1660 C CA  . VAL C 2 184 ? 130.521 116.002 105.382 1.00 81.94  ? 128 VAL R CA  1 
ATOM 1661 C C   . VAL C 2 184 ? 130.313 117.312 106.131 1.00 81.94  ? 128 VAL R C   1 
ATOM 1662 O O   . VAL C 2 184 ? 129.276 117.527 106.769 1.00 81.94  ? 128 VAL R O   1 
ATOM 1663 C CB  . VAL C 2 184 ? 131.454 115.051 106.152 1.00 81.94  ? 128 VAL R CB  1 
ATOM 1664 C CG1 . VAL C 2 184 ? 131.141 115.080 107.639 1.00 81.94  ? 128 VAL R CG1 1 
ATOM 1665 C CG2 . VAL C 2 184 ? 131.327 113.639 105.611 1.00 81.94  ? 128 VAL R CG2 1 
ATOM 1666 N N   . ASN C 2 185 ? 131.298 118.209 106.062 1.00 81.94  ? 129 ASN R N   1 
ATOM 1667 C CA  . ASN C 2 185 ? 131.160 119.503 106.720 1.00 81.94  ? 129 ASN R CA  1 
ATOM 1668 C C   . ASN C 2 185 ? 130.168 120.400 105.992 1.00 81.94  ? 129 ASN R C   1 
ATOM 1669 O O   . ASN C 2 185 ? 129.463 121.188 106.632 1.00 81.94  ? 129 ASN R O   1 
ATOM 1670 C CB  . ASN C 2 185 ? 132.521 120.187 106.817 1.00 81.94  ? 129 ASN R CB  1 
ATOM 1671 C CG  . ASN C 2 185 ? 133.476 119.449 107.731 1.00 81.94  ? 129 ASN R CG  1 
ATOM 1672 O OD1 . ASN C 2 185 ? 133.355 119.513 108.954 1.00 81.94  ? 129 ASN R OD1 1 
ATOM 1673 N ND2 . ASN C 2 185 ? 134.432 118.742 107.142 1.00 81.94  ? 129 ASN R ND2 1 
ATOM 1674 N N   . PHE C 2 186 ? 130.099 120.301 104.663 1.00 81.94  ? 130 PHE R N   1 
ATOM 1675 C CA  . PHE C 2 186 ? 129.134 121.096 103.913 1.00 81.94  ? 130 PHE R CA  1 
ATOM 1676 C C   . PHE C 2 186 ? 127.709 120.763 104.335 1.00 81.94  ? 130 PHE R C   1 
ATOM 1677 O O   . PHE C 2 186 ? 126.896 121.661 104.580 1.00 81.94  ? 130 PHE R O   1 
ATOM 1678 C CB  . PHE C 2 186 ? 129.319 120.864 102.414 1.00 81.94  ? 130 PHE R CB  1 
ATOM 1679 C CG  . PHE C 2 186 ? 128.080 121.117 101.603 1.00 81.94  ? 130 PHE R CG  1 
ATOM 1680 C CD1 . PHE C 2 186 ? 127.555 122.391 101.492 1.00 81.94  ? 130 PHE R CD1 1 
ATOM 1681 C CD2 . PHE C 2 186 ? 127.441 120.077 100.950 1.00 81.94  ? 130 PHE R CD2 1 
ATOM 1682 C CE1 . PHE C 2 186 ? 126.416 122.623 100.746 1.00 81.94  ? 130 PHE R CE1 1 
ATOM 1683 C CE2 . PHE C 2 186 ? 126.303 120.304 100.204 1.00 81.94  ? 130 PHE R CE2 1 
ATOM 1684 C CZ  . PHE C 2 186 ? 125.790 121.578 100.102 1.00 81.94  ? 130 PHE R CZ  1 
ATOM 1685 N N   . TYR C 2 187 ? 127.387 119.471 104.426 1.00 81.94  ? 131 TYR R N   1 
ATOM 1686 C CA  . TYR C 2 187 ? 126.058 119.075 104.878 1.00 81.94  ? 131 TYR R CA  1 
ATOM 1687 C C   . TYR C 2 187 ? 125.829 119.482 106.328 1.00 81.94  ? 131 TYR R C   1 
ATOM 1688 O O   . TYR C 2 187 ? 124.760 119.998 106.675 1.00 81.94  ? 131 TYR R O   1 
ATOM 1689 C CB  . TYR C 2 187 ? 125.877 117.567 104.712 1.00 81.94  ? 131 TYR R CB  1 
ATOM 1690 C CG  . TYR C 2 187 ? 125.387 117.157 103.344 1.00 81.94  ? 131 TYR R CG  1 
ATOM 1691 C CD1 . TYR C 2 187 ? 124.083 117.413 102.948 1.00 81.94  ? 131 TYR R CD1 1 
ATOM 1692 C CD2 . TYR C 2 187 ? 126.228 116.511 102.449 1.00 81.94  ? 131 TYR R CD2 1 
ATOM 1693 C CE1 . TYR C 2 187 ? 123.630 117.039 101.699 1.00 81.94  ? 131 TYR R CE1 1 
ATOM 1694 C CE2 . TYR C 2 187 ? 125.785 116.134 101.198 1.00 81.94  ? 131 TYR R CE2 1 
ATOM 1695 C CZ  . TYR C 2 187 ? 124.485 116.400 100.827 1.00 81.94  ? 131 TYR R CZ  1 
ATOM 1696 O OH  . TYR C 2 187 ? 124.038 116.026 99.581  1.00 81.94  ? 131 TYR R OH  1 
ATOM 1697 N N   . SER C 2 188 ? 126.822 119.256 107.190 1.00 81.94  ? 132 SER R N   1 
ATOM 1698 C CA  . SER C 2 188 ? 126.670 119.603 108.599 1.00 81.94  ? 132 SER R CA  1 
ATOM 1699 C C   . SER C 2 188 ? 126.521 121.106 108.783 1.00 81.94  ? 132 SER R C   1 
ATOM 1700 O O   . SER C 2 188 ? 125.695 121.562 109.583 1.00 81.94  ? 132 SER R O   1 
ATOM 1701 C CB  . SER C 2 188 ? 127.864 119.084 109.398 1.00 81.94  ? 132 SER R CB  1 
ATOM 1702 O OG  . SER C 2 188 ? 127.855 117.670 109.463 1.00 81.94  ? 132 SER R OG  1 
ATOM 1703 N N   . GLY C 2 189 ? 127.309 121.894 108.052 1.00 81.94  ? 133 GLY R N   1 
ATOM 1704 C CA  . GLY C 2 189 ? 127.226 123.338 108.197 1.00 81.94  ? 133 GLY R CA  1 
ATOM 1705 C C   . GLY C 2 189 ? 125.842 123.871 107.885 1.00 81.94  ? 133 GLY R C   1 
ATOM 1706 O O   . GLY C 2 189 ? 125.306 124.711 108.611 1.00 81.94  ? 133 GLY R O   1 
ATOM 1707 N N   . ILE C 2 190 ? 125.240 123.385 106.798 1.00 81.94  ? 134 ILE R N   1 
ATOM 1708 C CA  . ILE C 2 190 ? 123.918 123.866 106.405 1.00 81.94  ? 134 ILE R CA  1 
ATOM 1709 C C   . ILE C 2 190 ? 122.870 123.420 107.415 1.00 81.94  ? 134 ILE R C   1 
ATOM 1710 O O   . ILE C 2 190 ? 122.017 124.206 107.842 1.00 81.94  ? 134 ILE R O   1 
ATOM 1711 C CB  . ILE C 2 190 ? 123.569 123.381 104.987 1.00 81.94  ? 134 ILE R CB  1 
ATOM 1712 C CG1 . ILE C 2 190 ? 124.604 123.881 103.976 1.00 81.94  ? 134 ILE R CG1 1 
ATOM 1713 C CG2 . ILE C 2 190 ? 122.182 123.856 104.600 1.00 81.94  ? 134 ILE R CG2 1 
ATOM 1714 C CD1 . ILE C 2 190 ? 124.534 125.365 103.706 1.00 81.94  ? 134 ILE R CD1 1 
ATOM 1715 N N   . LEU C 2 191 ? 122.915 122.147 107.811 1.00 81.94  ? 135 LEU R N   1 
ATOM 1716 C CA  . LEU C 2 191 ? 121.900 121.625 108.719 1.00 81.94  ? 135 LEU R CA  1 
ATOM 1717 C C   . LEU C 2 191 ? 121.947 122.318 110.074 1.00 81.94  ? 135 LEU R C   1 
ATOM 1718 O O   . LEU C 2 191 ? 120.902 122.510 110.705 1.00 81.94  ? 135 LEU R O   1 
ATOM 1719 C CB  . LEU C 2 191 ? 122.071 120.116 108.885 1.00 67.61  ? 135 LEU R CB  1 
ATOM 1720 C CG  . LEU C 2 191 ? 121.737 119.270 107.654 1.00 67.61  ? 135 LEU R CG  1 
ATOM 1721 C CD1 . LEU C 2 191 ? 121.996 117.802 107.937 1.00 67.61  ? 135 LEU R CD1 1 
ATOM 1722 C CD2 . LEU C 2 191 ? 120.295 119.481 107.214 1.00 67.61  ? 135 LEU R CD2 1 
ATOM 1723 N N   . LEU C 2 192 ? 123.138 122.699 110.539 1.00 81.94  ? 136 LEU R N   1 
ATOM 1724 C CA  . LEU C 2 192 ? 123.223 123.453 111.784 1.00 81.94  ? 136 LEU R CA  1 
ATOM 1725 C C   . LEU C 2 192 ? 122.505 124.790 111.672 1.00 81.94  ? 136 LEU R C   1 
ATOM 1726 O O   . LEU C 2 192 ? 121.825 125.207 112.616 1.00 81.94  ? 136 LEU R O   1 
ATOM 1727 C CB  . LEU C 2 192 ? 124.686 123.669 112.174 1.00 81.94  ? 136 LEU R CB  1 
ATOM 1728 C CG  . LEU C 2 192 ? 125.464 122.463 112.708 1.00 81.94  ? 136 LEU R CG  1 
ATOM 1729 C CD1 . LEU C 2 192 ? 126.771 122.925 113.325 1.00 81.94  ? 136 LEU R CD1 1 
ATOM 1730 C CD2 . LEU C 2 192 ? 124.656 121.672 113.724 1.00 81.94  ? 136 LEU R CD2 1 
ATOM 1731 N N   . LEU C 2 193 ? 122.638 125.473 110.533 1.00 81.94  ? 137 LEU R N   1 
ATOM 1732 C CA  . LEU C 2 193 ? 121.899 126.715 110.334 1.00 81.94  ? 137 LEU R CA  1 
ATOM 1733 C C   . LEU C 2 193 ? 120.398 126.469 110.399 1.00 81.94  ? 137 LEU R C   1 
ATOM 1734 O O   . LEU C 2 193 ? 119.630 127.363 110.774 1.00 81.94  ? 137 LEU R O   1 
ATOM 1735 C CB  . LEU C 2 193 ? 122.279 127.344 108.994 1.00 81.94  ? 137 LEU R CB  1 
ATOM 1736 C CG  . LEU C 2 193 ? 123.753 127.700 108.787 1.00 81.94  ? 137 LEU R CG  1 
ATOM 1737 C CD1 . LEU C 2 193 ? 123.900 128.678 107.634 1.00 81.94  ? 137 LEU R CD1 1 
ATOM 1738 C CD2 . LEU C 2 193 ? 124.373 128.267 110.054 1.00 81.94  ? 137 LEU R CD2 1 
ATOM 1739 N N   . ALA C 2 194 ? 119.959 125.265 110.028 1.00 81.94  ? 138 ALA R N   1 
ATOM 1740 C CA  . ALA C 2 194 ? 118.551 124.917 110.185 1.00 81.94  ? 138 ALA R CA  1 
ATOM 1741 C C   . ALA C 2 194 ? 118.213 124.650 111.646 1.00 81.94  ? 138 ALA R C   1 
ATOM 1742 O O   . ALA C 2 194 ? 117.156 125.068 112.131 1.00 81.94  ? 138 ALA R O   1 
ATOM 1743 C CB  . ALA C 2 194 ? 118.212 123.702 109.324 1.00 81.94  ? 138 ALA R CB  1 
ATOM 1744 N N   . CYS C 2 195 ? 119.096 123.951 112.363 1.00 81.94  ? 139 CYS R N   1 
ATOM 1745 C CA  . CYS C 2 195 ? 118.859 123.700 113.780 1.00 81.94  ? 139 CYS R CA  1 
ATOM 1746 C C   . CYS C 2 195 ? 118.869 124.996 114.580 1.00 81.94  ? 139 CYS R C   1 
ATOM 1747 O O   . CYS C 2 195 ? 118.032 125.189 115.469 1.00 81.94  ? 139 CYS R O   1 
ATOM 1748 C CB  . CYS C 2 195 ? 119.905 122.728 114.324 1.00 81.94  ? 139 CYS R CB  1 
ATOM 1749 S SG  . CYS C 2 195 ? 119.591 120.998 113.916 1.00 81.94  ? 139 CYS R SG  1 
ATOM 1750 N N   . ILE C 2 196 ? 119.809 125.894 114.280 1.00 81.94  ? 140 ILE R N   1 
ATOM 1751 C CA  . ILE C 2 196 ? 119.869 127.167 114.991 1.00 81.94  ? 140 ILE R CA  1 
ATOM 1752 C C   . ILE C 2 196 ? 118.560 127.923 114.828 1.00 81.94  ? 140 ILE R C   1 
ATOM 1753 O O   . ILE C 2 196 ? 118.028 128.493 115.789 1.00 81.94  ? 140 ILE R O   1 
ATOM 1754 C CB  . ILE C 2 196 ? 121.065 128.000 114.495 1.00 81.94  ? 140 ILE R CB  1 
ATOM 1755 C CG1 . ILE C 2 196 ? 122.363 127.481 115.112 1.00 81.94  ? 140 ILE R CG1 1 
ATOM 1756 C CG2 . ILE C 2 196 ? 120.866 129.472 114.830 1.00 81.94  ? 140 ILE R CG2 1 
ATOM 1757 C CD1 . ILE C 2 196 ? 123.613 128.055 114.482 1.00 81.94  ? 140 ILE R CD1 1 
ATOM 1758 N N   . SER C 2 197 ? 118.019 127.943 113.610 1.00 81.94  ? 141 SER R N   1 
ATOM 1759 C CA  . SER C 2 197 ? 116.782 128.673 113.367 1.00 81.94  ? 141 SER R CA  1 
ATOM 1760 C C   . SER C 2 197 ? 115.626 128.079 114.161 1.00 81.94  ? 141 SER R C   1 
ATOM 1761 O O   . SER C 2 197 ? 114.791 128.817 114.697 1.00 81.94  ? 141 SER R O   1 
ATOM 1762 C CB  . SER C 2 197 ? 116.464 128.675 111.875 1.00 81.94  ? 141 SER R CB  1 
ATOM 1763 O OG  . SER C 2 197 ? 115.227 129.314 111.631 1.00 81.94  ? 141 SER R OG  1 
ATOM 1764 N N   . VAL C 2 198 ? 115.556 126.750 114.246 1.00 81.94  ? 142 VAL R N   1 
ATOM 1765 C CA  . VAL C 2 198 ? 114.511 126.116 115.042 1.00 81.94  ? 142 VAL R CA  1 
ATOM 1766 C C   . VAL C 2 198 ? 114.644 126.515 116.505 1.00 81.94  ? 142 VAL R C   1 
ATOM 1767 O O   . VAL C 2 198 ? 113.646 126.792 117.180 1.00 81.94  ? 142 VAL R O   1 
ATOM 1768 C CB  . VAL C 2 198 ? 114.560 124.587 114.871 1.00 81.94  ? 142 VAL R CB  1 
ATOM 1769 C CG1 . VAL C 2 198 ? 113.636 123.913 115.872 1.00 81.94  ? 142 VAL R CG1 1 
ATOM 1770 C CG2 . VAL C 2 198 ? 114.187 124.197 113.450 1.00 81.94  ? 142 VAL R CG2 1 
ATOM 1771 N N   . ASP C 2 199 ? 115.874 126.548 117.019 1.00 81.94  ? 143 ASP R N   1 
ATOM 1772 C CA  . ASP C 2 199 ? 116.085 126.945 118.407 1.00 81.94  ? 143 ASP R CA  1 
ATOM 1773 C C   . ASP C 2 199 ? 115.580 128.362 118.648 1.00 81.94  ? 143 ASP R C   1 
ATOM 1774 O O   . ASP C 2 199 ? 114.915 128.634 119.654 1.00 81.94  ? 143 ASP R O   1 
ATOM 1775 C CB  . ASP C 2 199 ? 117.567 126.835 118.760 1.00 81.94  ? 143 ASP R CB  1 
ATOM 1776 C CG  . ASP C 2 199 ? 117.841 127.129 120.219 1.00 81.94  ? 143 ASP R CG  1 
ATOM 1777 O OD1 . ASP C 2 199 ? 116.873 127.357 120.974 1.00 81.94  ? 143 ASP R OD1 1 
ATOM 1778 O OD2 . ASP C 2 199 ? 119.025 127.137 120.612 1.00 81.94  ? 143 ASP R OD2 1 
ATOM 1779 N N   . ARG C 2 200 ? 115.890 129.282 117.733 1.00 81.94  ? 144 ARG R N   1 
ATOM 1780 C CA  . ARG C 2 200 ? 115.412 130.653 117.877 1.00 81.94  ? 144 ARG R CA  1 
ATOM 1781 C C   . ARG C 2 200 ? 113.894 130.719 117.777 1.00 81.94  ? 144 ARG R C   1 
ATOM 1782 O O   . ARG C 2 200 ? 113.251 131.490 118.499 1.00 81.94  ? 144 ARG R O   1 
ATOM 1783 C CB  . ARG C 2 200 ? 116.064 131.547 116.823 1.00 81.94  ? 144 ARG R CB  1 
ATOM 1784 C CG  . ARG C 2 200 ? 117.533 131.814 117.088 1.00 81.94  ? 144 ARG R CG  1 
ATOM 1785 C CD  . ARG C 2 200 ? 118.224 132.417 115.881 1.00 81.94  ? 144 ARG R CD  1 
ATOM 1786 N NE  . ARG C 2 200 ? 119.576 132.855 116.199 1.00 81.94  ? 144 ARG R NE  1 
ATOM 1787 C CZ  . ARG C 2 200 ? 120.421 133.380 115.323 1.00 81.94  ? 144 ARG R CZ  1 
ATOM 1788 N NH1 . ARG C 2 200 ? 120.086 133.550 114.055 1.00 81.94  ? 144 ARG R NH1 1 
ATOM 1789 N NH2 . ARG C 2 200 ? 121.634 133.744 115.729 1.00 81.94  ? 144 ARG R NH2 1 
ATOM 1790 N N   . TYR C 2 201 ? 113.302 129.921 116.887 1.00 81.94  ? 145 TYR R N   1 
ATOM 1791 C CA  . TYR C 2 201 ? 111.848 129.912 116.756 1.00 81.94  ? 145 TYR R CA  1 
ATOM 1792 C C   . TYR C 2 201 ? 111.185 129.514 118.067 1.00 81.94  ? 145 TYR R C   1 
ATOM 1793 O O   . TYR C 2 201 ? 110.221 130.149 118.508 1.00 81.94  ? 145 TYR R O   1 
ATOM 1794 C CB  . TYR C 2 201 ? 111.433 128.960 115.634 1.00 81.94  ? 145 TYR R CB  1 
ATOM 1795 C CG  . TYR C 2 201 ? 109.966 128.599 115.644 1.00 81.94  ? 145 TYR R CG  1 
ATOM 1796 C CD1 . TYR C 2 201 ? 108.990 129.575 115.533 1.00 81.94  ? 145 TYR R CD1 1 
ATOM 1797 C CD2 . TYR C 2 201 ? 109.557 127.279 115.754 1.00 81.94  ? 145 TYR R CD2 1 
ATOM 1798 C CE1 . TYR C 2 201 ? 107.651 129.251 115.538 1.00 81.94  ? 145 TYR R CE1 1 
ATOM 1799 C CE2 . TYR C 2 201 ? 108.220 126.944 115.760 1.00 81.94  ? 145 TYR R CE2 1 
ATOM 1800 C CZ  . TYR C 2 201 ? 107.271 127.934 115.651 1.00 81.94  ? 145 TYR R CZ  1 
ATOM 1801 O OH  . TYR C 2 201 ? 105.935 127.607 115.656 1.00 81.94  ? 145 TYR R OH  1 
ATOM 1802 N N   . LEU C 2 202 ? 111.696 128.463 118.711 1.00 81.94  ? 146 LEU R N   1 
ATOM 1803 C CA  . LEU C 2 202 ? 111.125 128.030 119.981 1.00 81.94  ? 146 LEU R CA  1 
ATOM 1804 C C   . LEU C 2 202 ? 111.435 129.015 121.100 1.00 81.94  ? 146 LEU R C   1 
ATOM 1805 O O   . LEU C 2 202 ? 110.618 129.194 122.009 1.00 81.94  ? 146 LEU R O   1 
ATOM 1806 C CB  . LEU C 2 202 ? 111.650 126.641 120.342 1.00 81.94  ? 146 LEU R CB  1 
ATOM 1807 C CG  . LEU C 2 202 ? 111.166 125.488 119.461 1.00 81.94  ? 146 LEU R CG  1 
ATOM 1808 C CD1 . LEU C 2 202 ? 111.879 124.202 119.842 1.00 81.94  ? 146 LEU R CD1 1 
ATOM 1809 C CD2 . LEU C 2 202 ? 109.659 125.317 119.561 1.00 81.94  ? 146 LEU R CD2 1 
ATOM 1810 N N   . ALA C 2 203 ? 112.602 129.658 121.053 1.00 81.94  ? 147 ALA R N   1 
ATOM 1811 C CA  . ALA C 2 203 ? 112.996 130.567 122.122 1.00 81.94  ? 147 ALA R CA  1 
ATOM 1812 C C   . ALA C 2 203 ? 112.117 131.811 122.163 1.00 81.94  ? 147 ALA R C   1 
ATOM 1813 O O   . ALA C 2 203 ? 111.829 132.332 123.246 1.00 81.94  ? 147 ALA R O   1 
ATOM 1814 C CB  . ALA C 2 203 ? 114.462 130.965 121.955 1.00 81.94  ? 147 ALA R CB  1 
ATOM 1815 N N   . ILE C 2 204 ? 111.683 132.300 121.003 1.00 81.94  ? 148 ILE R N   1 
ATOM 1816 C CA  . ILE C 2 204 ? 110.952 133.560 120.927 1.00 81.94  ? 148 ILE R CA  1 
ATOM 1817 C C   . ILE C 2 204 ? 109.456 133.296 120.812 1.00 81.94  ? 148 ILE R C   1 
ATOM 1818 O O   . ILE C 2 204 ? 108.669 133.761 121.644 1.00 81.94  ? 148 ILE R O   1 
ATOM 1819 C CB  . ILE C 2 204 ? 111.450 134.412 119.746 1.00 81.94  ? 148 ILE R CB  1 
ATOM 1820 C CG1 . ILE C 2 204 ? 112.915 134.801 119.959 1.00 81.94  ? 148 ILE R CG1 1 
ATOM 1821 C CG2 . ILE C 2 204 ? 110.582 135.651 119.584 1.00 81.94  ? 148 ILE R CG2 1 
ATOM 1822 C CD1 . ILE C 2 204 ? 113.576 135.405 118.741 1.00 81.94  ? 148 ILE R CD1 1 
ATOM 1823 N N   . VAL C 2 205 ? 109.051 132.551 119.784 1.00 81.94  ? 149 VAL R N   1 
ATOM 1824 C CA  . VAL C 2 205 ? 107.626 132.345 119.535 1.00 81.94  ? 149 VAL R CA  1 
ATOM 1825 C C   . VAL C 2 205 ? 106.983 131.600 120.698 1.00 81.94  ? 149 VAL R C   1 
ATOM 1826 O O   . VAL C 2 205 ? 105.897 131.961 121.165 1.00 81.94  ? 149 VAL R O   1 
ATOM 1827 C CB  . VAL C 2 205 ? 107.417 131.601 118.204 1.00 81.94  ? 149 VAL R CB  1 
ATOM 1828 C CG1 . VAL C 2 205 ? 105.933 131.435 117.917 1.00 81.94  ? 149 VAL R CG1 1 
ATOM 1829 C CG2 . VAL C 2 205 ? 108.100 132.345 117.074 1.00 81.94  ? 149 VAL R CG2 1 
ATOM 1830 N N   . HIS C 2 206 ? 107.641 130.549 121.181 1.00 81.94  ? 150 HIS R N   1 
ATOM 1831 C CA  . HIS C 2 206 ? 107.131 129.721 122.270 1.00 81.94  ? 150 HIS R CA  1 
ATOM 1832 C C   . HIS C 2 206 ? 107.866 130.001 123.577 1.00 81.94  ? 150 HIS R C   1 
ATOM 1833 O O   . HIS C 2 206 ? 108.125 129.093 124.369 1.00 81.94  ? 150 HIS R O   1 
ATOM 1834 C CB  . HIS C 2 206 ? 107.232 128.240 121.916 1.00 81.94  ? 150 HIS R CB  1 
ATOM 1835 C CG  . HIS C 2 206 ? 106.370 127.835 120.762 1.00 81.94  ? 150 HIS R CG  1 
ATOM 1836 N ND1 . HIS C 2 206 ? 105.408 126.853 120.862 1.00 81.94  ? 150 HIS R ND1 1 
ATOM 1837 C CD2 . HIS C 2 206 ? 106.329 128.272 119.482 1.00 81.94  ? 150 HIS R CD2 1 
ATOM 1838 C CE1 . HIS C 2 206 ? 104.808 126.707 119.695 1.00 81.94  ? 150 HIS R CE1 1 
ATOM 1839 N NE2 . HIS C 2 206 ? 105.348 127.556 118.840 1.00 81.94  ? 150 HIS R NE2 1 
ATOM 1840 N N   . ALA C 2 207 ? 108.209 131.266 123.819 1.00 81.94  ? 151 ALA R N   1 
ATOM 1841 C CA  . ALA C 2 207 ? 108.919 131.612 125.045 1.00 81.94  ? 151 ALA R CA  1 
ATOM 1842 C C   . ALA C 2 207 ? 108.084 131.292 126.278 1.00 81.94  ? 151 ALA R C   1 
ATOM 1843 O O   . ALA C 2 207 ? 108.614 130.811 127.286 1.00 81.94  ? 151 ALA R O   1 
ATOM 1844 C CB  . ALA C 2 207 ? 109.299 133.091 125.029 1.00 81.94  ? 151 ALA R CB  1 
ATOM 1845 N N   . THR C 2 208 ? 106.778 131.555 126.219 1.00 81.94  ? 152 THR R N   1 
ATOM 1846 C CA  . THR C 2 208 ? 105.917 131.340 127.376 1.00 81.94  ? 152 THR R CA  1 
ATOM 1847 C C   . THR C 2 208 ? 105.666 129.863 127.654 1.00 81.94  ? 152 THR R C   1 
ATOM 1848 O O   . THR C 2 208 ? 105.734 129.436 128.811 1.00 81.94  ? 152 THR R O   1 
ATOM 1849 C CB  . THR C 2 208 ? 104.579 132.051 127.169 1.00 81.94  ? 152 THR R CB  1 
ATOM 1850 O OG1 . THR C 2 208 ? 104.805 133.450 126.962 1.00 81.94  ? 152 THR R OG1 1 
ATOM 1851 C CG2 . THR C 2 208 ? 103.678 131.861 128.378 1.00 81.94  ? 152 THR R CG2 1 
ATOM 1852 N N   . ARG C 2 209 ? 105.385 129.074 126.621 1.00 89.78  ? 153 ARG R N   1 
ATOM 1853 C CA  . ARG C 2 209 ? 104.896 127.715 126.794 1.00 89.78  ? 153 ARG R CA  1 
ATOM 1854 C C   . ARG C 2 209 ? 106.046 126.783 127.175 1.00 89.78  ? 153 ARG R C   1 
ATOM 1855 O O   . ARG C 2 209 ? 107.210 127.186 127.239 1.00 89.78  ? 153 ARG R O   1 
ATOM 1856 C CB  . ARG C 2 209 ? 104.184 127.264 125.522 1.00 89.78  ? 153 ARG R CB  1 
ATOM 1857 C CG  . ARG C 2 209 ? 102.969 128.113 125.191 1.00 89.78  ? 153 ARG R CG  1 
ATOM 1858 C CD  . ARG C 2 209 ? 102.310 127.699 123.888 1.00 89.78  ? 153 ARG R CD  1 
ATOM 1859 N NE  . ARG C 2 209 ? 101.253 128.628 123.505 1.00 89.78  ? 153 ARG R NE  1 
ATOM 1860 C CZ  . ARG C 2 209 ? 100.588 128.579 122.358 1.00 89.78  ? 153 ARG R CZ  1 
ATOM 1861 N NH1 . ARG C 2 209 ? 100.838 127.648 121.452 1.00 89.78  ? 153 ARG R NH1 1 
ATOM 1862 N NH2 . ARG C 2 209 ? 99.649  129.489 122.115 1.00 89.78  ? 153 ARG R NH2 1 
ATOM 1863 N N   . THR C 2 210 ? 105.722 125.515 127.434 1.00 92.68  ? 154 THR R N   1 
ATOM 1864 C CA  . THR C 2 210 ? 106.698 124.523 127.866 1.00 92.68  ? 154 THR R CA  1 
ATOM 1865 C C   . THR C 2 210 ? 107.346 123.795 126.698 1.00 92.68  ? 154 THR R C   1 
ATOM 1866 O O   . THR C 2 210 ? 108.271 123.004 126.910 1.00 92.68  ? 154 THR R O   1 
ATOM 1867 C CB  . THR C 2 210 ? 106.042 123.506 128.802 1.00 92.68  ? 154 THR R CB  1 
ATOM 1868 O OG1 . THR C 2 210 ? 104.899 122.929 128.160 1.00 92.68  ? 154 THR R OG1 1 
ATOM 1869 C CG2 . THR C 2 210 ? 105.610 124.171 130.098 1.00 92.68  ? 154 THR R CG2 1 
ATOM 1870 N N   . LEU C 2 211 ? 106.886 124.039 125.470 1.00 81.94  ? 155 LEU R N   1 
ATOM 1871 C CA  . LEU C 2 211 ? 107.528 123.434 124.312 1.00 81.94  ? 155 LEU R CA  1 
ATOM 1872 C C   . LEU C 2 211 ? 108.951 123.940 124.127 1.00 81.94  ? 155 LEU R C   1 
ATOM 1873 O O   . LEU C 2 211 ? 109.779 123.230 123.548 1.00 81.94  ? 155 LEU R O   1 
ATOM 1874 C CB  . LEU C 2 211 ? 106.707 123.708 123.052 1.00 80.20  ? 155 LEU R CB  1 
ATOM 1875 C CG  . LEU C 2 211 ? 107.227 123.077 121.759 1.00 80.20  ? 155 LEU R CG  1 
ATOM 1876 C CD1 . LEU C 2 211 ? 107.190 121.560 121.848 1.00 80.20  ? 155 LEU R CD1 1 
ATOM 1877 C CD2 . LEU C 2 211 ? 106.420 123.563 120.570 1.00 80.20  ? 155 LEU R CD2 1 
ATOM 1878 N N   . THR C 2 212 ? 109.252 125.148 124.608 1.00 81.97  ? 156 THR R N   1 
ATOM 1879 C CA  . THR C 2 212 ? 110.607 125.674 124.516 1.00 81.97  ? 156 THR R CA  1 
ATOM 1880 C C   . THR C 2 212 ? 111.597 124.863 125.339 1.00 81.97  ? 156 THR R C   1 
ATOM 1881 O O   . THR C 2 212 ? 112.806 124.976 125.116 1.00 81.97  ? 156 THR R O   1 
ATOM 1882 C CB  . THR C 2 212 ? 110.644 127.134 124.969 1.00 81.97  ? 156 THR R CB  1 
ATOM 1883 O OG1 . THR C 2 212 ? 111.963 127.661 124.780 1.00 81.97  ? 156 THR R OG1 1 
ATOM 1884 C CG2 . THR C 2 212 ? 110.266 127.250 126.438 1.00 81.97  ? 156 THR R CG2 1 
ATOM 1885 N N   . GLN C 2 213 ? 111.117 124.055 126.283 1.00 88.84  ? 157 GLN R N   1 
ATOM 1886 C CA  . GLN C 2 213 ? 111.993 123.206 127.078 1.00 88.84  ? 157 GLN R CA  1 
ATOM 1887 C C   . GLN C 2 213 ? 112.640 122.103 126.254 1.00 88.84  ? 157 GLN R C   1 
ATOM 1888 O O   . GLN C 2 213 ? 113.555 121.437 126.750 1.00 88.84  ? 157 GLN R O   1 
ATOM 1889 C CB  . GLN C 2 213 ? 111.214 122.584 128.239 1.00 88.84  ? 157 GLN R CB  1 
ATOM 1890 C CG  . GLN C 2 213 ? 110.635 123.591 129.219 1.00 88.84  ? 157 GLN R CG  1 
ATOM 1891 C CD  . GLN C 2 213 ? 111.683 124.522 129.797 1.00 88.84  ? 157 GLN R CD  1 
ATOM 1892 O OE1 . GLN C 2 213 ? 112.226 125.377 129.098 1.00 88.84  ? 157 GLN R OE1 1 
ATOM 1893 N NE2 . GLN C 2 213 ? 111.975 124.357 131.082 1.00 88.84  ? 157 GLN R NE2 1 
ATOM 1894 N N   . LYS C 2 214 ? 112.195 121.899 125.017 1.00 91.58  ? 158 LYS R N   1 
ATOM 1895 C CA  . LYS C 2 214 ? 112.764 120.892 124.138 1.00 91.58  ? 158 LYS R CA  1 
ATOM 1896 C C   . LYS C 2 214 ? 114.035 121.370 123.451 1.00 91.58  ? 158 LYS R C   1 
ATOM 1897 O O   . LYS C 2 214 ? 114.551 120.669 122.574 1.00 91.58  ? 158 LYS R O   1 
ATOM 1898 C CB  . LYS C 2 214 ? 111.735 120.477 123.084 1.00 91.58  ? 158 LYS R CB  1 
ATOM 1899 C CG  . LYS C 2 214 ? 110.483 119.837 123.661 1.00 91.58  ? 158 LYS R CG  1 
ATOM 1900 C CD  . LYS C 2 214 ? 109.933 118.756 122.747 1.00 91.58  ? 158 LYS R CD  1 
ATOM 1901 C CE  . LYS C 2 214 ? 108.797 117.996 123.413 1.00 91.58  ? 158 LYS R CE  1 
ATOM 1902 N NZ  . LYS C 2 214 ? 107.601 118.858 123.629 1.00 91.58  ? 158 LYS R NZ  1 
ATOM 1903 N N   . ARG C 2 215 ? 114.550 122.543 123.825 1.00 81.94  ? 159 ARG R N   1 
ATOM 1904 C CA  . ARG C 2 215 ? 115.772 123.082 123.243 1.00 81.94  ? 159 ARG R CA  1 
ATOM 1905 C C   . ARG C 2 215 ? 116.986 122.847 124.137 1.00 81.94  ? 159 ARG R C   1 
ATOM 1906 O O   . ARG C 2 215 ? 118.044 123.439 123.906 1.00 81.94  ? 159 ARG R O   1 
ATOM 1907 C CB  . ARG C 2 215 ? 115.608 124.574 122.946 1.00 80.31  ? 159 ARG R CB  1 
ATOM 1908 C CG  . ARG C 2 215 ? 115.785 125.488 124.147 1.00 80.31  ? 159 ARG R CG  1 
ATOM 1909 C CD  . ARG C 2 215 ? 115.284 126.892 123.843 1.00 80.31  ? 159 ARG R CD  1 
ATOM 1910 N NE  . ARG C 2 215 ? 115.943 127.903 124.665 1.00 80.31  ? 159 ARG R NE  1 
ATOM 1911 C CZ  . ARG C 2 215 ? 116.819 128.796 124.219 1.00 80.31  ? 159 ARG R CZ  1 
ATOM 1912 N NH1 . ARG C 2 215 ? 117.198 128.827 122.951 1.00 80.31  ? 159 ARG R NH1 1 
ATOM 1913 N NH2 . ARG C 2 215 ? 117.333 129.679 125.070 1.00 80.31  ? 159 ARG R NH2 1 
ATOM 1914 N N   . TYR C 2 216 ? 116.852 122.003 125.160 1.00 92.77  ? 160 TYR R N   1 
ATOM 1915 C CA  . TYR C 2 216 ? 117.980 121.564 125.969 1.00 92.77  ? 160 TYR R CA  1 
ATOM 1916 C C   . TYR C 2 216 ? 118.596 120.269 125.456 1.00 92.77  ? 160 TYR R C   1 
ATOM 1917 O O   . TYR C 2 216 ? 119.523 119.745 126.081 1.00 92.77  ? 160 TYR R O   1 
ATOM 1918 C CB  . TYR C 2 216 ? 117.554 121.390 127.428 1.00 92.77  ? 160 TYR R CB  1 
ATOM 1919 C CG  . TYR C 2 216 ? 117.207 122.682 128.129 1.00 92.77  ? 160 TYR R CG  1 
ATOM 1920 C CD1 . TYR C 2 216 ? 118.145 123.699 128.252 1.00 92.77  ? 160 TYR R CD1 1 
ATOM 1921 C CD2 . TYR C 2 216 ? 115.948 122.884 128.675 1.00 92.77  ? 160 TYR R CD2 1 
ATOM 1922 C CE1 . TYR C 2 216 ? 117.836 124.882 128.894 1.00 92.77  ? 160 TYR R CE1 1 
ATOM 1923 C CE2 . TYR C 2 216 ? 115.630 124.064 129.319 1.00 92.77  ? 160 TYR R CE2 1 
ATOM 1924 C CZ  . TYR C 2 216 ? 116.578 125.060 129.426 1.00 92.77  ? 160 TYR R CZ  1 
ATOM 1925 O OH  . TYR C 2 216 ? 116.267 126.237 130.067 1.00 92.77  ? 160 TYR R OH  1 
ATOM 1926 N N   . LEU C 2 217 ? 118.100 119.740 124.336 1.00 82.02  ? 161 LEU R N   1 
ATOM 1927 C CA  . LEU C 2 217 ? 118.659 118.552 123.704 1.00 82.02  ? 161 LEU R CA  1 
ATOM 1928 C C   . LEU C 2 217 ? 119.635 118.919 122.590 1.00 82.02  ? 161 LEU R C   1 
ATOM 1929 O O   . LEU C 2 217 ? 119.834 118.146 121.651 1.00 82.02  ? 161 LEU R O   1 
ATOM 1930 C CB  . LEU C 2 217 ? 117.547 117.658 123.157 1.00 82.02  ? 161 LEU R CB  1 
ATOM 1931 C CG  . LEU C 2 217 ? 116.261 117.582 123.981 1.00 82.02  ? 161 LEU R CG  1 
ATOM 1932 C CD1 . LEU C 2 217 ? 115.227 116.730 123.267 1.00 82.02  ? 161 LEU R CD1 1 
ATOM 1933 C CD2 . LEU C 2 217 ? 116.545 117.033 125.369 1.00 82.02  ? 161 LEU R CD2 1 
ATOM 1934 N N   . VAL C 2 218 ? 120.249 120.099 122.686 1.00 81.94  ? 162 VAL R N   1 
ATOM 1935 C CA  . VAL C 2 218 ? 121.218 120.516 121.677 1.00 81.94  ? 162 VAL R CA  1 
ATOM 1936 C C   . VAL C 2 218 ? 122.384 119.540 121.631 1.00 81.94  ? 162 VAL R C   1 
ATOM 1937 O O   . VAL C 2 218 ? 122.937 119.257 120.562 1.00 81.94  ? 162 VAL R O   1 
ATOM 1938 C CB  . VAL C 2 218 ? 121.696 121.953 121.955 1.00 70.14  ? 162 VAL R CB  1 
ATOM 1939 C CG1 . VAL C 2 218 ? 120.527 122.914 121.904 1.00 70.14  ? 162 VAL R CG1 1 
ATOM 1940 C CG2 . VAL C 2 218 ? 122.407 122.035 123.302 1.00 70.14  ? 162 VAL R CG2 1 
ATOM 1941 N N   . LYS C 2 219 ? 122.780 119.016 122.791 1.00 81.94  ? 163 LYS R N   1 
ATOM 1942 C CA  . LYS C 2 219 ? 123.899 118.084 122.845 1.00 81.94  ? 163 LYS R CA  1 
ATOM 1943 C C   . LYS C 2 219 ? 123.656 116.890 121.929 1.00 81.94  ? 163 LYS R C   1 
ATOM 1944 O O   . LYS C 2 219 ? 124.510 116.533 121.110 1.00 81.94  ? 163 LYS R O   1 
ATOM 1945 C CB  . LYS C 2 219 ? 124.116 117.629 124.289 1.00 70.54  ? 163 LYS R CB  1 
ATOM 1946 C CG  . LYS C 2 219 ? 125.398 116.844 124.512 1.00 70.54  ? 163 LYS R CG  1 
ATOM 1947 C CD  . LYS C 2 219 ? 125.469 116.240 125.913 1.00 70.54  ? 163 LYS R CD  1 
ATOM 1948 C CE  . LYS C 2 219 ? 125.107 117.242 127.002 1.00 70.54  ? 163 LYS R CE  1 
ATOM 1949 N NZ  . LYS C 2 219 ? 125.294 116.671 128.364 1.00 70.54  ? 163 LYS R NZ  1 
ATOM 1950 N N   . PHE C 2 220 ? 122.487 116.259 122.051 1.00 81.94  ? 164 PHE R N   1 
ATOM 1951 C CA  . PHE C 2 220 ? 122.185 115.110 121.205 1.00 81.94  ? 164 PHE R CA  1 
ATOM 1952 C C   . PHE C 2 220 ? 121.792 115.531 119.795 1.00 81.94  ? 164 PHE R C   1 
ATOM 1953 O O   . PHE C 2 220 ? 122.168 114.861 118.828 1.00 81.94  ? 164 PHE R O   1 
ATOM 1954 C CB  . PHE C 2 220 ? 121.076 114.268 121.834 1.00 67.37  ? 164 PHE R CB  1 
ATOM 1955 C CG  . PHE C 2 220 ? 121.557 113.332 122.908 1.00 67.37  ? 164 PHE R CG  1 
ATOM 1956 C CD1 . PHE C 2 220 ? 122.740 113.576 123.588 1.00 67.37  ? 164 PHE R CD1 1 
ATOM 1957 C CD2 . PHE C 2 220 ? 120.827 112.202 123.234 1.00 67.37  ? 164 PHE R CD2 1 
ATOM 1958 C CE1 . PHE C 2 220 ? 123.181 112.714 124.571 1.00 67.37  ? 164 PHE R CE1 1 
ATOM 1959 C CE2 . PHE C 2 220 ? 121.264 111.337 124.216 1.00 67.37  ? 164 PHE R CE2 1 
ATOM 1960 C CZ  . PHE C 2 220 ? 122.443 111.593 124.885 1.00 67.37  ? 164 PHE R CZ  1 
ATOM 1961 N N   . ILE C 2 221 ? 121.042 116.626 119.652 1.00 81.94  ? 165 ILE R N   1 
ATOM 1962 C CA  . ILE C 2 221 ? 120.608 117.038 118.320 1.00 81.94  ? 165 ILE R CA  1 
ATOM 1963 C C   . ILE C 2 221 ? 121.807 117.332 117.431 1.00 81.94  ? 165 ILE R C   1 
ATOM 1964 O O   . ILE C 2 221 ? 121.796 117.011 116.237 1.00 81.94  ? 165 ILE R O   1 
ATOM 1965 C CB  . ILE C 2 221 ? 119.665 118.252 118.404 1.00 81.94  ? 165 ILE R CB  1 
ATOM 1966 C CG1 . ILE C 2 221 ? 118.347 117.862 119.074 1.00 81.94  ? 165 ILE R CG1 1 
ATOM 1967 C CG2 . ILE C 2 221 ? 119.399 118.814 117.017 1.00 81.94  ? 165 ILE R CG2 1 
ATOM 1968 C CD1 . ILE C 2 221 ? 117.616 119.029 119.701 1.00 81.94  ? 165 ILE R CD1 1 
ATOM 1969 N N   . CYS C 2 222 ? 122.855 117.944 117.984 1.00 81.94  ? 166 CYS R N   1 
ATOM 1970 C CA  . CYS C 2 222 ? 124.062 118.176 117.200 1.00 81.94  ? 166 CYS R CA  1 
ATOM 1971 C C   . CYS C 2 222 ? 124.725 116.858 116.820 1.00 81.94  ? 166 CYS R C   1 
ATOM 1972 O O   . CYS C 2 222 ? 125.305 116.738 115.735 1.00 81.94  ? 166 CYS R O   1 
ATOM 1973 C CB  . CYS C 2 222 ? 125.027 119.066 117.980 1.00 81.94  ? 166 CYS R CB  1 
ATOM 1974 S SG  . CYS C 2 222 ? 124.596 120.818 117.919 1.00 81.94  ? 166 CYS R SG  1 
ATOM 1975 N N   . LEU C 2 223 ? 124.650 115.859 117.701 1.00 81.94  ? 167 LEU R N   1 
ATOM 1976 C CA  . LEU C 2 223 ? 125.150 114.533 117.354 1.00 81.94  ? 167 LEU R CA  1 
ATOM 1977 C C   . LEU C 2 223 ? 124.365 113.942 116.191 1.00 81.94  ? 167 LEU R C   1 
ATOM 1978 O O   . LEU C 2 223 ? 124.944 113.326 115.289 1.00 81.94  ? 167 LEU R O   1 
ATOM 1979 C CB  . LEU C 2 223 ? 125.076 113.614 118.573 1.00 81.94  ? 167 LEU R CB  1 
ATOM 1980 C CG  . LEU C 2 223 ? 125.642 112.205 118.395 1.00 81.94  ? 167 LEU R CG  1 
ATOM 1981 C CD1 . LEU C 2 223 ? 127.161 112.231 118.404 1.00 81.94  ? 167 LEU R CD1 1 
ATOM 1982 C CD2 . LEU C 2 223 ? 125.107 111.285 119.480 1.00 81.94  ? 167 LEU R CD2 1 
ATOM 1983 N N   . SER C 2 224 ? 123.043 114.118 116.196 1.00 81.94  ? 168 SER R N   1 
ATOM 1984 C CA  . SER C 2 224 ? 122.218 113.578 115.121 1.00 81.94  ? 168 SER R CA  1 
ATOM 1985 C C   . SER C 2 224 ? 122.587 114.202 113.781 1.00 81.94  ? 168 SER R C   1 
ATOM 1986 O O   . SER C 2 224 ? 122.703 113.503 112.768 1.00 81.94  ? 168 SER R O   1 
ATOM 1987 C CB  . SER C 2 224 ? 120.740 113.810 115.435 1.00 81.94  ? 168 SER R CB  1 
ATOM 1988 O OG  . SER C 2 224 ? 119.920 113.417 114.349 1.00 81.94  ? 168 SER R OG  1 
ATOM 1989 N N   . ILE C 2 225 ? 122.776 115.523 113.755 1.00 81.94  ? 169 ILE R N   1 
ATOM 1990 C CA  . ILE C 2 225 ? 123.109 116.196 112.503 1.00 81.94  ? 169 ILE R CA  1 
ATOM 1991 C C   . ILE C 2 225 ? 124.445 115.698 111.971 1.00 81.94  ? 169 ILE R C   1 
ATOM 1992 O O   . ILE C 2 225 ? 124.586 115.406 110.777 1.00 81.94  ? 169 ILE R O   1 
ATOM 1993 C CB  . ILE C 2 225 ? 123.117 117.723 112.703 1.00 81.94  ? 169 ILE R CB  1 
ATOM 1994 C CG1 . ILE C 2 225 ? 121.712 118.233 113.035 1.00 81.94  ? 169 ILE R CG1 1 
ATOM 1995 C CG2 . ILE C 2 225 ? 123.655 118.418 111.464 1.00 81.94  ? 169 ILE R CG2 1 
ATOM 1996 C CD1 . ILE C 2 225 ? 120.664 117.927 111.979 1.00 81.94  ? 169 ILE R CD1 1 
ATOM 1997 N N   . TRP C 2 226 ? 125.449 115.594 112.844 1.00 81.94  ? 170 TRP R N   1 
ATOM 1998 C CA  . TRP C 2 226 ? 126.749 115.100 112.407 1.00 81.94  ? 170 TRP R CA  1 
ATOM 1999 C C   . TRP C 2 226 ? 126.645 113.672 111.891 1.00 81.94  ? 170 TRP R C   1 
ATOM 2000 O O   . TRP C 2 226 ? 127.245 113.328 110.866 1.00 81.94  ? 170 TRP R O   1 
ATOM 2001 C CB  . TRP C 2 226 ? 127.754 115.185 113.554 1.00 81.94  ? 170 TRP R CB  1 
ATOM 2002 C CG  . TRP C 2 226 ? 128.390 116.533 113.683 1.00 81.94  ? 170 TRP R CG  1 
ATOM 2003 C CD1 . TRP C 2 226 ? 128.072 117.506 114.583 1.00 81.94  ? 170 TRP R CD1 1 
ATOM 2004 C CD2 . TRP C 2 226 ? 129.455 117.058 112.883 1.00 81.94  ? 170 TRP R CD2 1 
ATOM 2005 N NE1 . TRP C 2 226 ? 128.873 118.605 114.394 1.00 81.94  ? 170 TRP R NE1 1 
ATOM 2006 C CE2 . TRP C 2 226 ? 129.731 118.355 113.356 1.00 81.94  ? 170 TRP R CE2 1 
ATOM 2007 C CE3 . TRP C 2 226 ? 130.202 116.558 111.814 1.00 81.94  ? 170 TRP R CE3 1 
ATOM 2008 C CZ2 . TRP C 2 226 ? 130.721 119.157 112.797 1.00 81.94  ? 170 TRP R CZ2 1 
ATOM 2009 C CZ3 . TRP C 2 226 ? 131.184 117.355 111.260 1.00 81.94  ? 170 TRP R CZ3 1 
ATOM 2010 C CH2 . TRP C 2 226 ? 131.435 118.640 111.752 1.00 81.94  ? 170 TRP R CH2 1 
ATOM 2011 N N   . GLY C 2 227 ? 125.884 112.824 112.585 1.00 81.94  ? 171 GLY R N   1 
ATOM 2012 C CA  . GLY C 2 227 ? 125.701 111.462 112.114 1.00 81.94  ? 171 GLY R CA  1 
ATOM 2013 C C   . GLY C 2 227 ? 124.968 111.400 110.788 1.00 81.94  ? 171 GLY R C   1 
ATOM 2014 O O   . GLY C 2 227 ? 125.345 110.637 109.895 1.00 81.94  ? 171 GLY R O   1 
ATOM 2015 N N   . LEU C 2 228 ? 123.913 112.203 110.638 1.00 81.94  ? 172 LEU R N   1 
ATOM 2016 C CA  . LEU C 2 228 ? 123.167 112.216 109.385 1.00 81.94  ? 172 LEU R CA  1 
ATOM 2017 C C   . LEU C 2 228 ? 124.032 112.697 108.228 1.00 81.94  ? 172 LEU R C   1 
ATOM 2018 O O   . LEU C 2 228 ? 123.926 112.171 107.114 1.00 81.94  ? 172 LEU R O   1 
ATOM 2019 C CB  . LEU C 2 228 ? 121.925 113.098 109.527 1.00 81.94  ? 172 LEU R CB  1 
ATOM 2020 C CG  . LEU C 2 228 ? 121.139 113.401 108.249 1.00 81.94  ? 172 LEU R CG  1 
ATOM 2021 C CD1 . LEU C 2 228 ? 120.494 112.139 107.705 1.00 81.94  ? 172 LEU R CD1 1 
ATOM 2022 C CD2 . LEU C 2 228 ? 120.090 114.464 108.519 1.00 81.94  ? 172 LEU R CD2 1 
ATOM 2023 N N   . SER C 2 229 ? 124.887 113.693 108.467 1.00 81.94  ? 173 SER R N   1 
ATOM 2024 C CA  . SER C 2 229 ? 125.734 114.209 107.397 1.00 81.94  ? 173 SER R CA  1 
ATOM 2025 C C   . SER C 2 229 ? 126.659 113.127 106.857 1.00 81.94  ? 173 SER R C   1 
ATOM 2026 O O   . SER C 2 229 ? 126.826 112.996 105.639 1.00 81.94  ? 173 SER R O   1 
ATOM 2027 C CB  . SER C 2 229 ? 126.544 115.401 107.902 1.00 81.94  ? 173 SER R CB  1 
ATOM 2028 O OG  . SER C 2 229 ? 125.692 116.445 108.340 1.00 81.94  ? 173 SER R OG  1 
ATOM 2029 N N   . LEU C 2 230 ? 127.269 112.342 107.747 1.00 81.94  ? 174 LEU R N   1 
ATOM 2030 C CA  . LEU C 2 230 ? 128.149 111.268 107.300 1.00 81.94  ? 174 LEU R CA  1 
ATOM 2031 C C   . LEU C 2 230 ? 127.386 110.246 106.467 1.00 81.94  ? 174 LEU R C   1 
ATOM 2032 O O   . LEU C 2 230 ? 127.956 109.612 105.572 1.00 81.94  ? 174 LEU R O   1 
ATOM 2033 C CB  . LEU C 2 230 ? 128.804 110.599 108.508 1.00 81.94  ? 174 LEU R CB  1 
ATOM 2034 C CG  . LEU C 2 230 ? 129.677 109.377 108.223 1.00 81.94  ? 174 LEU R CG  1 
ATOM 2035 C CD1 . LEU C 2 230 ? 130.929 109.787 107.468 1.00 81.94  ? 174 LEU R CD1 1 
ATOM 2036 C CD2 . LEU C 2 230 ? 130.036 108.670 109.518 1.00 81.94  ? 174 LEU R CD2 1 
ATOM 2037 N N   . LEU C 2 231 ? 126.093 110.070 106.747 1.00 81.94  ? 175 LEU R N   1 
ATOM 2038 C CA  . LEU C 2 231 ? 125.291 109.130 105.971 1.00 81.94  ? 175 LEU R CA  1 
ATOM 2039 C C   . LEU C 2 231 ? 125.032 109.656 104.566 1.00 81.94  ? 175 LEU R C   1 
ATOM 2040 O O   . LEU C 2 231 ? 124.945 108.876 103.611 1.00 81.94  ? 175 LEU R O   1 
ATOM 2041 C CB  . LEU C 2 231 ? 123.972 108.851 106.691 1.00 81.94  ? 175 LEU R CB  1 
ATOM 2042 C CG  . LEU C 2 231 ? 123.001 107.905 105.982 1.00 81.94  ? 175 LEU R CG  1 
ATOM 2043 C CD1 . LEU C 2 231 ? 123.562 106.494 105.926 1.00 81.94  ? 175 LEU R CD1 1 
ATOM 2044 C CD2 . LEU C 2 231 ? 121.650 107.919 106.675 1.00 81.94  ? 175 LEU R CD2 1 
ATOM 2045 N N   . LEU C 2 232 ? 124.901 110.972 104.418 1.00 81.94  ? 176 LEU R N   1 
ATOM 2046 C CA  . LEU C 2 232 ? 124.622 111.584 103.127 1.00 81.94  ? 176 LEU R CA  1 
ATOM 2047 C C   . LEU C 2 232 ? 125.876 111.810 102.293 1.00 81.94  ? 176 LEU R C   1 
ATOM 2048 O O   . LEU C 2 232 ? 125.762 112.216 101.132 1.00 81.94  ? 176 LEU R O   1 
ATOM 2049 C CB  . LEU C 2 232 ? 123.897 112.920 103.327 1.00 81.94  ? 176 LEU R CB  1 
ATOM 2050 C CG  . LEU C 2 232 ? 122.439 112.854 103.788 1.00 81.94  ? 176 LEU R CG  1 
ATOM 2051 C CD1 . LEU C 2 232 ? 121.873 114.256 103.934 1.00 81.94  ? 176 LEU R CD1 1 
ATOM 2052 C CD2 . LEU C 2 232 ? 121.592 112.037 102.825 1.00 81.94  ? 176 LEU R CD2 1 
ATOM 2053 N N   . ALA C 2 233 ? 127.061 111.562 102.849 1.00 81.94  ? 177 ALA R N   1 
ATOM 2054 C CA  . ALA C 2 233 ? 128.315 111.727 102.126 1.00 81.94  ? 177 ALA R CA  1 
ATOM 2055 C C   . ALA C 2 233 ? 128.913 110.398 101.683 1.00 81.94  ? 177 ALA R C   1 
ATOM 2056 O O   . ALA C 2 233 ? 129.968 110.388 101.042 1.00 81.94  ? 177 ALA R O   1 
ATOM 2057 C CB  . ALA C 2 233 ? 129.323 112.490 102.987 1.00 81.94  ? 177 ALA R CB  1 
ATOM 2058 N N   . LEU C 2 234 ? 128.270 109.279 102.012 1.00 81.94  ? 178 LEU R N   1 
ATOM 2059 C CA  . LEU C 2 234 ? 128.787 107.985 101.578 1.00 81.94  ? 178 LEU R CA  1 
ATOM 2060 C C   . LEU C 2 234 ? 128.896 107.873 100.064 1.00 81.94  ? 178 LEU R C   1 
ATOM 2061 O O   . LEU C 2 234 ? 129.920 107.356 99.584  1.00 81.94  ? 178 LEU R O   1 
ATOM 2062 C CB  . LEU C 2 234 ? 127.908 106.860 102.138 1.00 81.94  ? 178 LEU R CB  1 
ATOM 2063 C CG  . LEU C 2 234 ? 128.092 106.512 103.618 1.00 81.94  ? 178 LEU R CG  1 
ATOM 2064 C CD1 . LEU C 2 234 ? 127.192 105.348 103.997 1.00 81.94  ? 178 LEU R CD1 1 
ATOM 2065 C CD2 . LEU C 2 234 ? 129.545 106.189 103.936 1.00 81.94  ? 178 LEU R CD2 1 
ATOM 2066 N N   . PRO C 2 235 ? 127.920 108.314 99.267  1.00 81.94  ? 179 PRO R N   1 
ATOM 2067 C CA  . PRO C 2 235 ? 128.059 108.171 97.809  1.00 81.94  ? 179 PRO R CA  1 
ATOM 2068 C C   . PRO C 2 235 ? 129.326 108.805 97.266  1.00 81.94  ? 179 PRO R C   1 
ATOM 2069 O O   . PRO C 2 235 ? 129.911 108.293 96.304  1.00 81.94  ? 179 PRO R O   1 
ATOM 2070 C CB  . PRO C 2 235 ? 126.797 108.861 97.277  1.00 81.94  ? 179 PRO R CB  1 
ATOM 2071 C CG  . PRO C 2 235 ? 125.813 108.732 98.383  1.00 81.94  ? 179 PRO R CG  1 
ATOM 2072 C CD  . PRO C 2 235 ? 126.621 108.904 99.633  1.00 81.94  ? 179 PRO R CD  1 
ATOM 2073 N N   . VAL C 2 236 ? 129.768 109.913 97.861  1.00 81.94  ? 180 VAL R N   1 
ATOM 2074 C CA  . VAL C 2 236 ? 131.025 110.524 97.447  1.00 81.94  ? 180 VAL R CA  1 
ATOM 2075 C C   . VAL C 2 236 ? 132.187 109.573 97.703  1.00 81.94  ? 180 VAL R C   1 
ATOM 2076 O O   . VAL C 2 236 ? 133.078 109.421 96.860  1.00 81.94  ? 180 VAL R O   1 
ATOM 2077 C CB  . VAL C 2 236 ? 131.218 111.870 98.170  1.00 81.94  ? 180 VAL R CB  1 
ATOM 2078 C CG1 . VAL C 2 236 ? 132.690 112.243 98.245  1.00 81.94  ? 180 VAL R CG1 1 
ATOM 2079 C CG2 . VAL C 2 236 ? 130.432 112.960 97.464  1.00 81.94  ? 180 VAL R CG2 1 
ATOM 2080 N N   . LEU C 2 237 ? 132.200 108.921 98.866  1.00 81.94  ? 181 LEU R N   1 
ATOM 2081 C CA  . LEU C 2 237 ? 133.288 108.003 99.187  1.00 81.94  ? 181 LEU R CA  1 
ATOM 2082 C C   . LEU C 2 237 ? 133.238 106.753 98.316  1.00 81.94  ? 181 LEU R C   1 
ATOM 2083 O O   . LEU C 2 237 ? 134.282 106.241 97.896  1.00 81.94  ? 181 LEU R O   1 
ATOM 2084 C CB  . LEU C 2 237 ? 133.226 107.626 100.667 1.00 81.94  ? 181 LEU R CB  1 
ATOM 2085 C CG  . LEU C 2 237 ? 134.387 106.793 101.213 1.00 81.94  ? 181 LEU R CG  1 
ATOM 2086 C CD1 . LEU C 2 237 ? 135.560 107.682 101.581 1.00 81.94  ? 181 LEU R CD1 1 
ATOM 2087 C CD2 . LEU C 2 237 ? 133.933 105.982 102.414 1.00 81.94  ? 181 LEU R CD2 1 
ATOM 2088 N N   . LEU C 2 238 ? 132.036 106.249 98.034  1.00 81.94  ? 182 LEU R N   1 
ATOM 2089 C CA  . LEU C 2 238 ? 131.914 104.978 97.328  1.00 81.94  ? 182 LEU R CA  1 
ATOM 2090 C C   . LEU C 2 238 ? 132.231 105.123 95.844  1.00 81.94  ? 182 LEU R C   1 
ATOM 2091 O O   . LEU C 2 238 ? 132.835 104.226 95.245  1.00 81.94  ? 182 LEU R O   1 
ATOM 2092 C CB  . LEU C 2 238 ? 130.506 104.413 97.511  1.00 81.94  ? 182 LEU R CB  1 
ATOM 2093 C CG  . LEU C 2 238 ? 130.059 104.137 98.947  1.00 81.94  ? 182 LEU R CG  1 
ATOM 2094 C CD1 . LEU C 2 238 ? 128.603 103.703 98.974  1.00 81.94  ? 182 LEU R CD1 1 
ATOM 2095 C CD2 . LEU C 2 238 ? 130.943 103.086 99.597  1.00 81.94  ? 182 LEU R CD2 1 
ATOM 2096 N N   . PHE C 2 239 ? 131.833 106.239 95.234  1.00 81.94  ? 183 PHE R N   1 
ATOM 2097 C CA  . PHE C 2 239 ? 131.846 106.357 93.781  1.00 81.94  ? 183 PHE R CA  1 
ATOM 2098 C C   . PHE C 2 239 ? 132.706 107.511 93.279  1.00 81.94  ? 183 PHE R C   1 
ATOM 2099 O O   . PHE C 2 239 ? 132.249 108.289 92.437  1.00 81.94  ? 183 PHE R O   1 
ATOM 2100 C CB  . PHE C 2 239 ? 130.420 106.540 93.255  1.00 81.94  ? 183 PHE R CB  1 
ATOM 2101 C CG  . PHE C 2 239 ? 129.461 105.478 93.708  1.00 81.94  ? 183 PHE R CG  1 
ATOM 2102 C CD1 . PHE C 2 239 ? 129.747 104.139 93.520  1.00 81.94  ? 183 PHE R CD1 1 
ATOM 2103 C CD2 . PHE C 2 239 ? 128.264 105.823 94.312  1.00 81.94  ? 183 PHE R CD2 1 
ATOM 2104 C CE1 . PHE C 2 239 ? 128.862 103.163 93.932  1.00 81.94  ? 183 PHE R CE1 1 
ATOM 2105 C CE2 . PHE C 2 239 ? 127.376 104.852 94.726  1.00 81.94  ? 183 PHE R CE2 1 
ATOM 2106 C CZ  . PHE C 2 239 ? 127.676 103.520 94.535  1.00 81.94  ? 183 PHE R CZ  1 
ATOM 2107 N N   . ARG C 2 240 ? 133.932 107.651 93.781  1.00 81.94  ? 184 ARG R N   1 
ATOM 2108 C CA  . ARG C 2 240 ? 134.821 108.707 93.316  1.00 81.94  ? 184 ARG R CA  1 
ATOM 2109 C C   . ARG C 2 240 ? 136.200 108.144 93.011  1.00 81.94  ? 184 ARG R C   1 
ATOM 2110 O O   . ARG C 2 240 ? 136.681 107.243 93.703  1.00 81.94  ? 184 ARG R O   1 
ATOM 2111 C CB  . ARG C 2 240 ? 134.947 109.835 94.344  1.00 81.94  ? 184 ARG R CB  1 
ATOM 2112 C CG  . ARG C 2 240 ? 134.032 111.012 94.066  1.00 81.94  ? 184 ARG R CG  1 
ATOM 2113 C CD  . ARG C 2 240 ? 134.421 112.233 94.877  1.00 81.94  ? 184 ARG R CD  1 
ATOM 2114 N NE  . ARG C 2 240 ? 133.326 113.195 94.955  1.00 81.94  ? 184 ARG R NE  1 
ATOM 2115 C CZ  . ARG C 2 240 ? 133.406 114.475 94.615  1.00 81.94  ? 184 ARG R CZ  1 
ATOM 2116 N NH1 . ARG C 2 240 ? 134.533 115.010 94.172  1.00 81.94  ? 184 ARG R NH1 1 
ATOM 2117 N NH2 . ARG C 2 240 ? 132.325 115.242 94.723  1.00 81.94  ? 184 ARG R NH2 1 
ATOM 2118 N N   . ARG C 2 241 ? 136.827 108.685 91.970  1.00 81.94  ? 185 ARG R N   1 
ATOM 2119 C CA  . ARG C 2 241 ? 138.182 108.312 91.588  1.00 81.94  ? 185 ARG R CA  1 
ATOM 2120 C C   . ARG C 2 241 ? 138.687 109.340 90.586  1.00 81.94  ? 185 ARG R C   1 
ATOM 2121 O O   . ARG C 2 241 ? 137.921 110.154 90.064  1.00 81.94  ? 185 ARG R O   1 
ATOM 2122 C CB  . ARG C 2 241 ? 138.233 106.898 91.001  1.00 81.94  ? 185 ARG R CB  1 
ATOM 2123 C CG  . ARG C 2 241 ? 137.950 106.835 89.509  1.00 81.94  ? 185 ARG R CG  1 
ATOM 2124 C CD  . ARG C 2 241 ? 137.689 105.410 89.050  1.00 81.94  ? 185 ARG R CD  1 
ATOM 2125 N NE  . ARG C 2 241 ? 138.247 105.146 87.728  1.00 81.94  ? 185 ARG R NE  1 
ATOM 2126 C CZ  . ARG C 2 241 ? 137.849 105.739 86.610  1.00 81.94  ? 185 ARG R CZ  1 
ATOM 2127 N NH1 . ARG C 2 241 ? 136.889 106.648 86.612  1.00 81.94  ? 185 ARG R NH1 1 
ATOM 2128 N NH2 . ARG C 2 241 ? 138.431 105.412 85.460  1.00 81.94  ? 185 ARG R NH2 1 
ATOM 2129 N N   . THR C 2 242 ? 139.990 109.296 90.320  1.00 81.94  ? 186 THR R N   1 
ATOM 2130 C CA  . THR C 2 242 ? 140.591 110.182 89.330  1.00 81.94  ? 186 THR R CA  1 
ATOM 2131 C C   . THR C 2 242 ? 140.253 109.669 87.937  1.00 81.94  ? 186 THR R C   1 
ATOM 2132 O O   . THR C 2 242 ? 140.517 108.505 87.619  1.00 81.94  ? 186 THR R O   1 
ATOM 2133 C CB  . THR C 2 242 ? 142.104 110.262 89.513  1.00 81.94  ? 186 THR R CB  1 
ATOM 2134 O OG1 . THR C 2 242 ? 142.709 109.049 89.048  1.00 81.94  ? 186 THR R OG1 1 
ATOM 2135 C CG2 . THR C 2 242 ? 142.458 110.475 90.972  1.00 81.94  ? 186 THR R CG2 1 
ATOM 2136 N N   . VAL C 2 243 ? 139.673 110.532 87.112  1.00 81.94  ? 187 VAL R N   1 
ATOM 2137 C CA  . VAL C 2 243 ? 139.214 110.155 85.777  1.00 81.94  ? 187 VAL R CA  1 
ATOM 2138 C C   . VAL C 2 243 ? 140.133 110.855 84.782  1.00 81.94  ? 187 VAL R C   1 
ATOM 2139 O O   . VAL C 2 243 ? 139.908 111.999 84.387  1.00 81.94  ? 187 VAL R O   1 
ATOM 2140 C CB  . VAL C 2 243 ? 137.748 110.516 85.559  1.00 81.94  ? 187 VAL R CB  1 
ATOM 2141 C CG1 . VAL C 2 243 ? 137.238 109.905 84.265  1.00 81.94  ? 187 VAL R CG1 1 
ATOM 2142 C CG2 . VAL C 2 243 ? 136.915 110.049 86.738  1.00 81.94  ? 187 VAL R CG2 1 
ATOM 2143 N N   . TYR C 2 244 ? 141.184 110.154 84.367  1.00 81.94  ? 188 TYR R N   1 
ATOM 2144 C CA  . TYR C 2 244 ? 142.051 110.668 83.320  1.00 81.94  ? 188 TYR R CA  1 
ATOM 2145 C C   . TYR C 2 244 ? 141.283 110.786 82.011  1.00 81.94  ? 188 TYR R C   1 
ATOM 2146 O O   . TYR C 2 244 ? 140.447 109.943 81.675  1.00 81.94  ? 188 TYR R O   1 
ATOM 2147 C CB  . TYR C 2 244 ? 143.264 109.757 83.134  1.00 81.94  ? 188 TYR R CB  1 
ATOM 2148 C CG  . TYR C 2 244 ? 144.209 109.750 84.313  1.00 81.94  ? 188 TYR R CG  1 
ATOM 2149 C CD1 . TYR C 2 244 ? 145.178 110.732 84.454  1.00 81.94  ? 188 TYR R CD1 1 
ATOM 2150 C CD2 . TYR C 2 244 ? 144.130 108.765 85.287  1.00 81.94  ? 188 TYR R CD2 1 
ATOM 2151 C CE1 . TYR C 2 244 ? 146.043 110.733 85.528  1.00 81.94  ? 188 TYR R CE1 1 
ATOM 2152 C CE2 . TYR C 2 244 ? 144.991 108.758 86.366  1.00 81.94  ? 188 TYR R CE2 1 
ATOM 2153 C CZ  . TYR C 2 244 ? 145.946 109.745 86.481  1.00 81.94  ? 188 TYR R CZ  1 
ATOM 2154 O OH  . TYR C 2 244 ? 146.807 109.744 87.553  1.00 81.94  ? 188 TYR R OH  1 
ATOM 2155 N N   . SER C 2 245 ? 141.573 111.850 81.268  1.00 91.70  ? 189 SER R N   1 
ATOM 2156 C CA  . SER C 2 245 ? 140.916 112.110 79.994  1.00 91.70  ? 189 SER R CA  1 
ATOM 2157 C C   . SER C 2 245 ? 141.970 112.602 79.010  1.00 91.70  ? 189 SER R C   1 
ATOM 2158 O O   . SER C 2 245 ? 143.167 112.629 79.310  1.00 91.70  ? 189 SER R O   1 
ATOM 2159 C CB  . SER C 2 245 ? 139.771 113.115 80.171  1.00 91.70  ? 189 SER R CB  1 
ATOM 2160 O OG  . SER C 2 245 ? 138.857 113.039 79.092  1.00 91.70  ? 189 SER R OG  1 
ATOM 2161 N N   . SER C 2 246 ? 141.517 112.996 77.821  1.00 97.47  ? 190 SER R N   1 
ATOM 2162 C CA  . SER C 2 246 ? 142.394 113.510 76.776  1.00 97.47  ? 190 SER R CA  1 
ATOM 2163 C C   . SER C 2 246 ? 142.268 115.019 76.608  1.00 97.47  ? 190 SER R C   1 
ATOM 2164 O O   . SER C 2 246 ? 143.275 115.732 76.627  1.00 97.47  ? 190 SER R O   1 
ATOM 2165 C CB  . SER C 2 246 ? 142.087 112.811 75.447  1.00 97.47  ? 190 SER R CB  1 
ATOM 2166 O OG  . SER C 2 246 ? 140.762 113.084 75.025  1.00 97.47  ? 190 SER R OG  1 
ATOM 2167 N N   . ASN C 2 247 ? 141.043 115.520 76.442  1.00 105.76 ? 191 ASN R N   1 
ATOM 2168 C CA  . ASN C 2 247 ? 140.847 116.958 76.289  1.00 105.76 ? 191 ASN R CA  1 
ATOM 2169 C C   . ASN C 2 247 ? 141.174 117.706 77.575  1.00 105.76 ? 191 ASN R C   1 
ATOM 2170 O O   . ASN C 2 247 ? 141.742 118.803 77.533  1.00 105.76 ? 191 ASN R O   1 
ATOM 2171 C CB  . ASN C 2 247 ? 139.410 117.248 75.858  1.00 105.76 ? 191 ASN R CB  1 
ATOM 2172 C CG  . ASN C 2 247 ? 139.170 116.955 74.391  1.00 105.76 ? 191 ASN R CG  1 
ATOM 2173 O OD1 . ASN C 2 247 ? 140.112 116.803 73.614  1.00 105.76 ? 191 ASN R OD1 1 
ATOM 2174 N ND2 . ASN C 2 247 ? 137.902 116.881 74.004  1.00 105.76 ? 191 ASN R ND2 1 
ATOM 2175 N N   . VAL C 2 248 ? 140.826 117.131 78.725  1.00 102.75 ? 192 VAL R N   1 
ATOM 2176 C CA  . VAL C 2 248 ? 140.917 117.822 80.003  1.00 102.75 ? 192 VAL R CA  1 
ATOM 2177 C C   . VAL C 2 248 ? 141.930 117.112 80.891  1.00 102.75 ? 192 VAL R C   1 
ATOM 2178 O O   . VAL C 2 248 ? 142.230 115.929 80.720  1.00 102.75 ? 192 VAL R O   1 
ATOM 2179 C CB  . VAL C 2 248 ? 139.545 117.904 80.704  1.00 102.75 ? 192 VAL R CB  1 
ATOM 2180 C CG1 . VAL C 2 248 ? 139.625 118.782 81.944  1.00 102.75 ? 192 VAL R CG1 1 
ATOM 2181 C CG2 . VAL C 2 248 ? 138.491 118.428 79.741  1.00 102.75 ? 192 VAL R CG2 1 
ATOM 2182 N N   . SER C 2 249 ? 142.459 117.865 81.854  1.00 91.72  ? 193 SER R N   1 
ATOM 2183 C CA  . SER C 2 249 ? 143.388 117.329 82.830  1.00 91.72  ? 193 SER R CA  1 
ATOM 2184 C C   . SER C 2 249 ? 142.635 116.446 83.820  1.00 91.72  ? 193 SER R C   1 
ATOM 2185 O O   . SER C 2 249 ? 141.405 116.479 83.888  1.00 91.72  ? 193 SER R O   1 
ATOM 2186 C CB  . SER C 2 249 ? 144.108 118.468 83.549  1.00 91.72  ? 193 SER R CB  1 
ATOM 2187 O OG  . SER C 2 249 ? 143.191 119.287 84.251  1.00 91.72  ? 193 SER R OG  1 
ATOM 2188 N N   . PRO C 2 250 ? 143.350 115.637 84.602  1.00 81.94  ? 194 PRO R N   1 
ATOM 2189 C CA  . PRO C 2 250 ? 142.670 114.698 85.501  1.00 81.94  ? 194 PRO R CA  1 
ATOM 2190 C C   . PRO C 2 250 ? 141.724 115.413 86.453  1.00 81.94  ? 194 PRO R C   1 
ATOM 2191 O O   . PRO C 2 250 ? 141.997 116.518 86.924  1.00 81.94  ? 194 PRO R O   1 
ATOM 2192 C CB  . PRO C 2 250 ? 143.827 114.035 86.256  1.00 81.94  ? 194 PRO R CB  1 
ATOM 2193 C CG  . PRO C 2 250 ? 144.983 114.156 85.328  1.00 81.94  ? 194 PRO R CG  1 
ATOM 2194 C CD  . PRO C 2 250 ? 144.814 115.495 84.680  1.00 81.94  ? 194 PRO R CD  1 
ATOM 2195 N N   . ALA C 2 251 ? 140.595 114.763 86.731  1.00 81.94  ? 195 ALA R N   1 
ATOM 2196 C CA  . ALA C 2 251 ? 139.572 115.319 87.602  1.00 81.94  ? 195 ALA R CA  1 
ATOM 2197 C C   . ALA C 2 251 ? 139.119 114.262 88.596  1.00 81.94  ? 195 ALA R C   1 
ATOM 2198 O O   . ALA C 2 251 ? 139.096 113.067 88.290  1.00 81.94  ? 195 ALA R O   1 
ATOM 2199 C CB  . ALA C 2 251 ? 138.369 115.827 86.799  1.00 81.94  ? 195 ALA R CB  1 
ATOM 2200 N N   . CYS C 2 252 ? 138.754 114.716 89.795  1.00 81.94  ? 196 CYS R N   1 
ATOM 2201 C CA  . CYS C 2 252 ? 138.234 113.832 90.840  1.00 81.94  ? 196 CYS R CA  1 
ATOM 2202 C C   . CYS C 2 252 ? 136.719 113.706 90.669  1.00 81.94  ? 196 CYS R C   1 
ATOM 2203 O O   . CYS C 2 252 ? 135.914 114.277 91.408  1.00 81.94  ? 196 CYS R O   1 
ATOM 2204 C CB  . CYS C 2 252 ? 138.620 114.359 92.218  1.00 81.94  ? 196 CYS R CB  1 
ATOM 2205 S SG  . CYS C 2 252 ? 137.757 113.616 93.631  1.00 81.94  ? 196 CYS R SG  1 
ATOM 2206 N N   . TYR C 2 253 ? 136.343 112.934 89.653  1.00 81.94  ? 197 TYR R N   1 
ATOM 2207 C CA  . TYR C 2 253 ? 134.959 112.737 89.258  1.00 81.94  ? 197 TYR R CA  1 
ATOM 2208 C C   . TYR C 2 253 ? 134.436 111.429 89.849  1.00 81.94  ? 197 TYR R C   1 
ATOM 2209 O O   . TYR C 2 253 ? 135.117 110.759 90.630  1.00 81.94  ? 197 TYR R O   1 
ATOM 2210 C CB  . TYR C 2 253 ? 134.857 112.750 87.731  1.00 81.94  ? 197 TYR R CB  1 
ATOM 2211 C CG  . TYR C 2 253 ? 133.520 113.209 87.194  1.00 81.94  ? 197 TYR R CG  1 
ATOM 2212 C CD1 . TYR C 2 253 ? 133.068 114.502 87.411  1.00 81.94  ? 197 TYR R CD1 1 
ATOM 2213 C CD2 . TYR C 2 253 ? 132.713 112.346 86.468  1.00 81.94  ? 197 TYR R CD2 1 
ATOM 2214 C CE1 . TYR C 2 253 ? 131.848 114.922 86.920  1.00 81.94  ? 197 TYR R CE1 1 
ATOM 2215 C CE2 . TYR C 2 253 ? 131.493 112.756 85.974  1.00 81.94  ? 197 TYR R CE2 1 
ATOM 2216 C CZ  . TYR C 2 253 ? 131.066 114.044 86.201  1.00 81.94  ? 197 TYR R CZ  1 
ATOM 2217 O OH  . TYR C 2 253 ? 129.849 114.455 85.709  1.00 81.94  ? 197 TYR R OH  1 
ATOM 2218 N N   . GLU C 2 254 ? 133.214 111.057 89.476  1.00 81.94  ? 198 GLU R N   1 
ATOM 2219 C CA  . GLU C 2 254 ? 132.581 109.835 89.948  1.00 81.94  ? 198 GLU R CA  1 
ATOM 2220 C C   . GLU C 2 254 ? 132.562 108.785 88.844  1.00 81.94  ? 198 GLU R C   1 
ATOM 2221 O O   . GLU C 2 254 ? 132.524 109.111 87.655  1.00 81.94  ? 198 GLU R O   1 
ATOM 2222 C CB  . GLU C 2 254 ? 131.150 110.103 90.425  1.00 81.94  ? 198 GLU R CB  1 
ATOM 2223 C CG  . GLU C 2 254 ? 131.061 110.934 91.697  1.00 81.94  ? 198 GLU R CG  1 
ATOM 2224 C CD  . GLU C 2 254 ? 130.915 112.420 91.427  1.00 81.94  ? 198 GLU R CD  1 
ATOM 2225 O OE1 . GLU C 2 254 ? 130.958 112.824 90.247  1.00 81.94  ? 198 GLU R OE1 1 
ATOM 2226 O OE2 . GLU C 2 254 ? 130.754 113.186 92.400  1.00 81.94  ? 198 GLU R OE2 1 
ATOM 2227 N N   . ASP C 2 255 ? 132.588 107.512 89.254  1.00 74.99  ? 199 ASP R N   1 
ATOM 2228 C CA  . ASP C 2 255 ? 132.588 106.367 88.337  1.00 74.99  ? 199 ASP R CA  1 
ATOM 2229 C C   . ASP C 2 255 ? 131.580 105.347 88.862  1.00 74.99  ? 199 ASP R C   1 
ATOM 2230 O O   . ASP C 2 255 ? 131.924 104.469 89.655  1.00 74.99  ? 199 ASP R O   1 
ATOM 2231 C CB  . ASP C 2 255 ? 133.989 105.771 88.217  1.00 74.99  ? 199 ASP R CB  1 
ATOM 2232 C CG  . ASP C 2 255 ? 134.072 104.677 87.170  1.00 74.99  ? 199 ASP R CG  1 
ATOM 2233 O OD1 . ASP C 2 255 ? 133.232 103.753 87.200  1.00 74.99  ? 199 ASP R OD1 1 
ATOM 2234 O OD2 . ASP C 2 255 ? 134.984 104.737 86.320  1.00 74.99  ? 199 ASP R OD2 1 
ATOM 2235 N N   . MET C 2 256 ? 130.332 105.460 88.409  1.00 76.87  ? 200 MET R N   1 
ATOM 2236 C CA  . MET C 2 256 ? 129.258 104.581 88.854  1.00 76.87  ? 200 MET R CA  1 
ATOM 2237 C C   . MET C 2 256 ? 128.914 103.502 87.835  1.00 76.87  ? 200 MET R C   1 
ATOM 2238 O O   . MET C 2 256 ? 127.950 102.758 88.042  1.00 76.87  ? 200 MET R O   1 
ATOM 2239 C CB  . MET C 2 256 ? 128.009 105.400 89.180  1.00 76.87  ? 200 MET R CB  1 
ATOM 2240 C CG  . MET C 2 256 ? 128.187 106.349 90.348  1.00 76.87  ? 200 MET R CG  1 
ATOM 2241 S SD  . MET C 2 256 ? 126.836 107.530 90.490  1.00 76.87  ? 200 MET R SD  1 
ATOM 2242 C CE  . MET C 2 256 ? 127.727 108.981 91.041  1.00 76.87  ? 200 MET R CE  1 
ATOM 2243 N N   . GLY C 2 257 ? 129.664 103.399 86.747  1.00 69.36  ? 201 GLY R N   1 
ATOM 2244 C CA  . GLY C 2 257 ? 129.445 102.375 85.752  1.00 69.36  ? 201 GLY R CA  1 
ATOM 2245 C C   . GLY C 2 257 ? 129.186 102.992 84.396  1.00 69.36  ? 201 GLY R C   1 
ATOM 2246 O O   . GLY C 2 257 ? 129.362 104.192 84.191  1.00 69.36  ? 201 GLY R O   1 
ATOM 2247 N N   . ASN C 2 258 ? 128.757 102.145 83.457  1.00 77.18  ? 202 ASN R N   1 
ATOM 2248 C CA  . ASN C 2 258 ? 128.532 102.607 82.092  1.00 77.18  ? 202 ASN R CA  1 
ATOM 2249 C C   . ASN C 2 258 ? 127.514 103.737 82.040  1.00 77.18  ? 202 ASN R C   1 
ATOM 2250 O O   . ASN C 2 258 ? 127.634 104.642 81.206  1.00 77.18  ? 202 ASN R O   1 
ATOM 2251 C CB  . ASN C 2 258 ? 128.067 101.445 81.215  1.00 77.18  ? 202 ASN R CB  1 
ATOM 2252 C CG  . ASN C 2 258 ? 129.127 100.375 81.053  1.00 77.18  ? 202 ASN R CG  1 
ATOM 2253 O OD1 . ASN C 2 258 ? 128.894 99.206  81.356  1.00 77.18  ? 202 ASN R OD1 1 
ATOM 2254 N ND2 . ASN C 2 258 ? 130.301 100.770 80.574  1.00 77.18  ? 202 ASN R ND2 1 
ATOM 2255 N N   . ASN C 2 259 ? 126.513 103.709 82.917  1.00 81.88  ? 203 ASN R N   1 
ATOM 2256 C CA  . ASN C 2 259 ? 125.458 104.720 82.949  1.00 81.88  ? 203 ASN R CA  1 
ATOM 2257 C C   . ASN C 2 259 ? 125.725 105.776 84.012  1.00 81.88  ? 203 ASN R C   1 
ATOM 2258 O O   . ASN C 2 259 ? 124.796 106.304 84.629  1.00 81.88  ? 203 ASN R O   1 
ATOM 2259 C CB  . ASN C 2 259 ? 124.104 104.055 83.178  1.00 81.88  ? 203 ASN R CB  1 
ATOM 2260 C CG  . ASN C 2 259 ? 123.025 104.596 82.262  1.00 81.88  ? 203 ASN R CG  1 
ATOM 2261 O OD1 . ASN C 2 259 ? 123.307 105.076 81.165  1.00 81.88  ? 203 ASN R OD1 1 
ATOM 2262 N ND2 . ASN C 2 259 ? 121.778 104.520 82.711  1.00 81.88  ? 203 ASN R ND2 1 
ATOM 2263 N N   . THR C 2 260 ? 126.998 106.107 84.239  1.00 74.15  ? 204 THR R N   1 
ATOM 2264 C CA  . THR C 2 260 ? 127.341 107.066 85.282  1.00 74.15  ? 204 THR R CA  1 
ATOM 2265 C C   . THR C 2 260 ? 126.733 108.435 85.015  1.00 74.15  ? 204 THR R C   1 
ATOM 2266 O O   . THR C 2 260 ? 126.444 109.178 85.960  1.00 74.15  ? 204 THR R O   1 
ATOM 2267 C CB  . THR C 2 260 ? 128.860 107.185 85.403  1.00 74.15  ? 204 THR R CB  1 
ATOM 2268 O OG1 . THR C 2 260 ? 129.407 105.934 85.839  1.00 74.15  ? 204 THR R OG1 1 
ATOM 2269 C CG2 . THR C 2 260 ? 129.237 108.275 86.393  1.00 74.15  ? 204 THR R CG2 1 
ATOM 2270 N N   . ALA C 2 261 ? 126.533 108.790 83.745  1.00 75.32  ? 205 ALA R N   1 
ATOM 2271 C CA  . ALA C 2 261 ? 126.008 110.113 83.425  1.00 75.32  ? 205 ALA R CA  1 
ATOM 2272 C C   . ALA C 2 261 ? 124.624 110.317 84.030  1.00 75.32  ? 205 ALA R C   1 
ATOM 2273 O O   . ALA C 2 261 ? 124.341 111.366 84.618  1.00 75.32  ? 205 ALA R O   1 
ATOM 2274 C CB  . ALA C 2 261 ? 125.968 110.307 81.910  1.00 75.32  ? 205 ALA R CB  1 
ATOM 2275 N N   . ASN C 2 262 ? 123.745 109.321 83.894  1.00 78.32  ? 206 ASN R N   1 
ATOM 2276 C CA  . ASN C 2 262 ? 122.405 109.443 84.459  1.00 78.32  ? 206 ASN R CA  1 
ATOM 2277 C C   . ASN C 2 262 ? 122.425 109.269 85.973  1.00 78.32  ? 206 ASN R C   1 
ATOM 2278 O O   . ASN C 2 262 ? 121.745 110.004 86.698  1.00 78.32  ? 206 ASN R O   1 
ATOM 2279 C CB  . ASN C 2 262 ? 121.471 108.421 83.814  1.00 78.32  ? 206 ASN R CB  1 
ATOM 2280 C CG  . ASN C 2 262 ? 121.418 108.554 82.306  1.00 78.32  ? 206 ASN R CG  1 
ATOM 2281 O OD1 . ASN C 2 262 ? 122.222 109.267 81.707  1.00 78.32  ? 206 ASN R OD1 1 
ATOM 2282 N ND2 . ASN C 2 262 ? 120.467 107.868 81.684  1.00 78.32  ? 206 ASN R ND2 1 
ATOM 2283 N N   . TRP C 2 263 ? 123.199 108.301 86.470  1.00 76.78  ? 207 TRP R N   1 
ATOM 2284 C CA  . TRP C 2 263 ? 123.230 108.050 87.907  1.00 76.78  ? 207 TRP R CA  1 
ATOM 2285 C C   . TRP C 2 263 ? 123.775 109.245 88.677  1.00 76.78  ? 207 TRP R C   1 
ATOM 2286 O O   . TRP C 2 263 ? 123.285 109.549 89.770  1.00 76.78  ? 207 TRP R O   1 
ATOM 2287 C CB  . TRP C 2 263 ? 124.060 106.801 88.206  1.00 76.78  ? 207 TRP R CB  1 
ATOM 2288 C CG  . TRP C 2 263 ? 123.442 105.528 87.699  1.00 76.78  ? 207 TRP R CG  1 
ATOM 2289 C CD1 . TRP C 2 263 ? 124.057 104.558 86.965  1.00 76.78  ? 207 TRP R CD1 1 
ATOM 2290 C CD2 . TRP C 2 263 ? 122.094 105.083 87.901  1.00 76.78  ? 207 TRP R CD2 1 
ATOM 2291 N NE1 . TRP C 2 263 ? 123.176 103.541 86.690  1.00 76.78  ? 207 TRP R NE1 1 
ATOM 2292 C CE2 . TRP C 2 263 ? 121.965 103.839 87.255  1.00 76.78  ? 207 TRP R CE2 1 
ATOM 2293 C CE3 . TRP C 2 263 ? 120.984 105.616 88.564  1.00 76.78  ? 207 TRP R CE3 1 
ATOM 2294 C CZ2 . TRP C 2 263 ? 120.772 103.121 87.250  1.00 76.78  ? 207 TRP R CZ2 1 
ATOM 2295 C CZ3 . TRP C 2 263 ? 119.801 104.902 88.557  1.00 76.78  ? 207 TRP R CZ3 1 
ATOM 2296 C CH2 . TRP C 2 263 ? 119.704 103.668 87.905  1.00 76.78  ? 207 TRP R CH2 1 
ATOM 2297 N N   . ARG C 2 264 ? 124.781 109.932 88.134  1.00 81.94  ? 208 ARG R N   1 
ATOM 2298 C CA  . ARG C 2 264 ? 125.307 111.113 88.810  1.00 81.94  ? 208 ARG R CA  1 
ATOM 2299 C C   . ARG C 2 264 ? 124.221 112.160 89.011  1.00 81.94  ? 208 ARG R C   1 
ATOM 2300 O O   . ARG C 2 264 ? 124.182 112.833 90.047  1.00 81.94  ? 208 ARG R O   1 
ATOM 2301 C CB  . ARG C 2 264 ? 126.467 111.705 88.013  1.00 79.26  ? 208 ARG R CB  1 
ATOM 2302 C CG  . ARG C 2 264 ? 127.181 112.832 88.737  1.00 79.26  ? 208 ARG R CG  1 
ATOM 2303 C CD  . ARG C 2 264 ? 128.594 113.030 88.219  1.00 79.26  ? 208 ARG R CD  1 
ATOM 2304 N NE  . ARG C 2 264 ? 129.148 114.314 88.634  1.00 79.26  ? 208 ARG R NE  1 
ATOM 2305 C CZ  . ARG C 2 264 ? 128.726 115.492 88.195  1.00 79.26  ? 208 ARG R CZ  1 
ATOM 2306 N NH1 . ARG C 2 264 ? 127.750 115.592 87.308  1.00 79.26  ? 208 ARG R NH1 1 
ATOM 2307 N NH2 . ARG C 2 264 ? 129.301 116.599 88.656  1.00 79.26  ? 208 ARG R NH2 1 
ATOM 2308 N N   . MET C 2 265 ? 123.331 112.314 88.030  1.00 83.04  ? 209 MET R N   1 
ATOM 2309 C CA  . MET C 2 265 ? 122.271 113.309 88.146  1.00 83.04  ? 209 MET R CA  1 
ATOM 2310 C C   . MET C 2 265 ? 121.336 112.985 89.305  1.00 83.04  ? 209 MET R C   1 
ATOM 2311 O O   . MET C 2 265 ? 120.899 113.889 90.027  1.00 83.04  ? 209 MET R O   1 
ATOM 2312 C CB  . MET C 2 265 ? 121.499 113.396 86.832  1.00 83.04  ? 209 MET R CB  1 
ATOM 2313 C CG  . MET C 2 265 ? 122.317 113.973 85.688  1.00 83.04  ? 209 MET R CG  1 
ATOM 2314 S SD  . MET C 2 265 ? 121.629 113.596 84.067  1.00 83.04  ? 209 MET R SD  1 
ATOM 2315 C CE  . MET C 2 265 ? 120.342 114.833 83.947  1.00 83.04  ? 209 MET R CE  1 
ATOM 2316 N N   . LEU C 2 266 ? 121.015 111.704 89.500  1.00 81.94  ? 210 LEU R N   1 
ATOM 2317 C CA  . LEU C 2 266 ? 120.176 111.325 90.632  1.00 81.94  ? 210 LEU R CA  1 
ATOM 2318 C C   . LEU C 2 266 ? 120.858 111.648 91.954  1.00 81.94  ? 210 LEU R C   1 
ATOM 2319 O O   . LEU C 2 266 ? 120.216 112.150 92.884  1.00 81.94  ? 210 LEU R O   1 
ATOM 2320 C CB  . LEU C 2 266 ? 119.834 109.836 90.561  1.00 81.94  ? 210 LEU R CB  1 
ATOM 2321 C CG  . LEU C 2 266 ? 118.865 109.375 89.468  1.00 81.94  ? 210 LEU R CG  1 
ATOM 2322 C CD1 . LEU C 2 266 ? 118.396 107.958 89.757  1.00 81.94  ? 210 LEU R CD1 1 
ATOM 2323 C CD2 . LEU C 2 266 ? 117.674 110.312 89.333  1.00 81.94  ? 210 LEU R CD2 1 
ATOM 2324 N N   . LEU C 2 267 ? 122.159 111.368 92.060  1.00 81.94  ? 211 LEU R N   1 
ATOM 2325 C CA  . LEU C 2 267 ? 122.880 111.667 93.291  1.00 81.94  ? 211 LEU R CA  1 
ATOM 2326 C C   . LEU C 2 267 ? 122.865 113.153 93.614  1.00 81.94  ? 211 LEU R C   1 
ATOM 2327 O O   . LEU C 2 267 ? 123.023 113.523 94.782  1.00 81.94  ? 211 LEU R O   1 
ATOM 2328 C CB  . LEU C 2 267 ? 124.327 111.182 93.190  1.00 81.94  ? 211 LEU R CB  1 
ATOM 2329 C CG  . LEU C 2 267 ? 124.578 109.677 93.072  1.00 81.94  ? 211 LEU R CG  1 
ATOM 2330 C CD1 . LEU C 2 267 ? 125.901 109.332 93.733  1.00 81.94  ? 211 LEU R CD1 1 
ATOM 2331 C CD2 . LEU C 2 267 ? 123.448 108.850 93.673  1.00 81.94  ? 211 LEU R CD2 1 
ATOM 2332 N N   . ARG C 2 268 ? 122.684 114.012 92.610  1.00 82.33  ? 212 ARG R N   1 
ATOM 2333 C CA  . ARG C 2 268 ? 122.592 115.443 92.860  1.00 82.33  ? 212 ARG R CA  1 
ATOM 2334 C C   . ARG C 2 268 ? 121.304 115.827 93.572  1.00 82.33  ? 212 ARG R C   1 
ATOM 2335 O O   . ARG C 2 268 ? 121.188 116.967 94.033  1.00 82.33  ? 212 ARG R O   1 
ATOM 2336 C CB  . ARG C 2 268 ? 122.702 116.215 91.544  1.00 82.33  ? 212 ARG R CB  1 
ATOM 2337 C CG  . ARG C 2 268 ? 124.081 116.807 91.292  1.00 82.33  ? 212 ARG R CG  1 
ATOM 2338 C CD  . ARG C 2 268 ? 124.016 117.999 90.356  1.00 82.33  ? 212 ARG R CD  1 
ATOM 2339 N NE  . ARG C 2 268 ? 123.697 117.606 88.987  1.00 82.33  ? 212 ARG R NE  1 
ATOM 2340 C CZ  . ARG C 2 268 ? 124.426 117.900 87.918  1.00 82.33  ? 212 ARG R CZ  1 
ATOM 2341 N NH1 . ARG C 2 268 ? 125.543 118.604 88.007  1.00 82.33  ? 212 ARG R NH1 1 
ATOM 2342 N NH2 . ARG C 2 268 ? 124.023 117.476 86.723  1.00 82.33  ? 212 ARG R NH2 1 
ATOM 2343 N N   . ILE C 2 269 ? 120.339 114.911 93.673  1.00 81.94  ? 213 ILE R N   1 
ATOM 2344 C CA  . ILE C 2 269 ? 119.105 115.214 94.388  1.00 81.94  ? 213 ILE R CA  1 
ATOM 2345 C C   . ILE C 2 269 ? 119.382 115.402 95.875  1.00 81.94  ? 213 ILE R C   1 
ATOM 2346 O O   . ILE C 2 269 ? 118.754 116.237 96.535  1.00 81.94  ? 213 ILE R O   1 
ATOM 2347 C CB  . ILE C 2 269 ? 118.059 114.111 94.134  1.00 81.94  ? 213 ILE R CB  1 
ATOM 2348 C CG1 . ILE C 2 269 ? 116.647 114.699 94.172  1.00 81.94  ? 213 ILE R CG1 1 
ATOM 2349 C CG2 . ILE C 2 269 ? 118.193 112.979 95.145  1.00 81.94  ? 213 ILE R CG2 1 
ATOM 2350 C CD1 . ILE C 2 269 ? 115.581 113.749 93.675  1.00 81.94  ? 213 ILE R CD1 1 
ATOM 2351 N N   . LEU C 2 270 ? 120.324 114.632 96.426  1.00 81.94  ? 214 LEU R N   1 
ATOM 2352 C CA  . LEU C 2 270 ? 120.627 114.742 97.853  1.00 81.94  ? 214 LEU R CA  1 
ATOM 2353 C C   . LEU C 2 270 ? 121.122 116.133 98.227  1.00 81.94  ? 214 LEU R C   1 
ATOM 2354 O O   . LEU C 2 270 ? 120.560 116.743 99.153  1.00 81.94  ? 214 LEU R O   1 
ATOM 2355 C CB  . LEU C 2 270 ? 121.632 113.656 98.241  1.00 81.94  ? 214 LEU R CB  1 
ATOM 2356 C CG  . LEU C 2 270 ? 121.172 112.213 98.028  1.00 81.94  ? 214 LEU R CG  1 
ATOM 2357 C CD1 . LEU C 2 270 ? 122.302 111.248 98.340  1.00 81.94  ? 214 LEU R CD1 1 
ATOM 2358 C CD2 . LEU C 2 270 ? 119.951 111.898 98.876  1.00 81.94  ? 214 LEU R CD2 1 
ATOM 2359 N N   . PRO C 2 271 ? 122.145 116.691 97.575  1.00 81.94  ? 215 PRO R N   1 
ATOM 2360 C CA  . PRO C 2 271 ? 122.540 118.070 97.905  1.00 81.94  ? 215 PRO R CA  1 
ATOM 2361 C C   . PRO C 2 271 ? 121.448 119.088 97.639  1.00 81.94  ? 215 PRO R C   1 
ATOM 2362 O O   . PRO C 2 271 ? 121.365 120.094 98.354  1.00 81.94  ? 215 PRO R O   1 
ATOM 2363 C CB  . PRO C 2 271 ? 123.769 118.314 97.017  1.00 81.94  ? 215 PRO R CB  1 
ATOM 2364 C CG  . PRO C 2 271 ? 123.743 117.249 95.983  1.00 81.94  ? 215 PRO R CG  1 
ATOM 2365 C CD  . PRO C 2 271 ? 123.050 116.078 96.590  1.00 81.94  ? 215 PRO R CD  1 
ATOM 2366 N N   . GLN C 2 272 ? 120.607 118.863 96.633  1.00 84.27  ? 216 GLN R N   1 
ATOM 2367 C CA  . GLN C 2 272 ? 119.571 119.817 96.261  1.00 84.27  ? 216 GLN R CA  1 
ATOM 2368 C C   . GLN C 2 272 ? 118.244 119.561 96.962  1.00 84.27  ? 216 GLN R C   1 
ATOM 2369 O O   . GLN C 2 272 ? 117.289 120.310 96.734  1.00 84.27  ? 216 GLN R O   1 
ATOM 2370 C CB  . GLN C 2 272 ? 119.357 119.794 94.746  1.00 84.27  ? 216 GLN R CB  1 
ATOM 2371 C CG  . GLN C 2 272 ? 120.573 120.222 93.947  1.00 84.27  ? 216 GLN R CG  1 
ATOM 2372 C CD  . GLN C 2 272 ? 120.209 120.736 92.571  1.00 84.27  ? 216 GLN R CD  1 
ATOM 2373 O OE1 . GLN C 2 272 ? 120.148 119.974 91.607  1.00 84.27  ? 216 GLN R OE1 1 
ATOM 2374 N NE2 . GLN C 2 272 ? 119.965 122.037 92.473  1.00 84.27  ? 216 GLN R NE2 1 
ATOM 2375 N N   . SER C 2 273 ? 118.157 118.530 97.800  1.00 88.40  ? 217 SER R N   1 
ATOM 2376 C CA  . SER C 2 273 ? 116.954 118.238 98.568  1.00 88.40  ? 217 SER R CA  1 
ATOM 2377 C C   . SER C 2 273 ? 117.173 118.391 100.064 1.00 88.40  ? 217 SER R C   1 
ATOM 2378 O O   . SER C 2 273 ? 116.415 119.100 100.733 1.00 88.40  ? 217 SER R O   1 
ATOM 2379 C CB  . SER C 2 273 ? 116.466 116.816 98.259  1.00 88.40  ? 217 SER R CB  1 
ATOM 2380 O OG  . SER C 2 273 ? 117.471 115.862 98.552  1.00 88.40  ? 217 SER R OG  1 
ATOM 2381 N N   . PHE C 2 274 ? 118.198 117.742 100.609 1.00 89.78  ? 218 PHE R N   1 
ATOM 2382 C CA  . PHE C 2 274 ? 118.558 117.875 102.013 1.00 89.78  ? 218 PHE R CA  1 
ATOM 2383 C C   . PHE C 2 274 ? 119.610 118.950 102.248 1.00 89.78  ? 218 PHE R C   1 
ATOM 2384 O O   . PHE C 2 274 ? 120.069 119.109 103.383 1.00 89.78  ? 218 PHE R O   1 
ATOM 2385 C CB  . PHE C 2 274 ? 119.062 116.536 102.558 1.00 89.78  ? 218 PHE R CB  1 
ATOM 2386 C CG  . PHE C 2 274 ? 117.969 115.546 102.836 1.00 89.78  ? 218 PHE R CG  1 
ATOM 2387 C CD1 . PHE C 2 274 ? 117.242 114.982 101.801 1.00 89.78  ? 218 PHE R CD1 1 
ATOM 2388 C CD2 . PHE C 2 274 ? 117.665 115.183 104.136 1.00 89.78  ? 218 PHE R CD2 1 
ATOM 2389 C CE1 . PHE C 2 274 ? 116.236 114.072 102.059 1.00 89.78  ? 218 PHE R CE1 1 
ATOM 2390 C CE2 . PHE C 2 274 ? 116.660 114.274 104.400 1.00 89.78  ? 218 PHE R CE2 1 
ATOM 2391 C CZ  . PHE C 2 274 ? 115.945 113.718 103.360 1.00 89.78  ? 218 PHE R CZ  1 
ATOM 2392 N N   . GLY C 2 275 ? 120.002 119.684 101.209 1.00 81.94  ? 219 GLY R N   1 
ATOM 2393 C CA  . GLY C 2 275 ? 121.040 120.685 101.345 1.00 81.94  ? 219 GLY R CA  1 
ATOM 2394 C C   . GLY C 2 275 ? 120.572 122.095 101.055 1.00 81.94  ? 219 GLY R C   1 
ATOM 2395 O O   . GLY C 2 275 ? 121.104 123.051 101.625 1.00 81.94  ? 219 GLY R O   1 
ATOM 2396 N N   . PHE C 2 276 ? 119.589 122.247 100.166 1.00 78.48  ? 220 PHE R N   1 
ATOM 2397 C CA  . PHE C 2 276 ? 119.083 123.575 99.838  1.00 78.48  ? 220 PHE R CA  1 
ATOM 2398 C C   . PHE C 2 276 ? 117.610 123.744 100.188 1.00 78.48  ? 220 PHE R C   1 
ATOM 2399 O O   . PHE C 2 276 ? 117.248 124.668 100.921 1.00 78.48  ? 220 PHE R O   1 
ATOM 2400 C CB  . PHE C 2 276 ? 119.288 123.871 98.352  1.00 78.48  ? 220 PHE R CB  1 
ATOM 2401 C CG  . PHE C 2 276 ? 118.918 125.273 97.964  1.00 78.48  ? 220 PHE R CG  1 
ATOM 2402 C CD1 . PHE C 2 276 ? 119.495 126.357 98.603  1.00 78.48  ? 220 PHE R CD1 1 
ATOM 2403 C CD2 . PHE C 2 276 ? 117.986 125.508 96.967  1.00 78.48  ? 220 PHE R CD2 1 
ATOM 2404 C CE1 . PHE C 2 276 ? 119.155 127.647 98.252  1.00 78.48  ? 220 PHE R CE1 1 
ATOM 2405 C CE2 . PHE C 2 276 ? 117.643 126.797 96.613  1.00 78.48  ? 220 PHE R CE2 1 
ATOM 2406 C CZ  . PHE C 2 276 ? 118.228 127.867 97.257  1.00 78.48  ? 220 PHE R CZ  1 
ATOM 2407 N N   . ILE C 2 277 ? 116.752 122.860 99.677  1.00 81.94  ? 221 ILE R N   1 
ATOM 2408 C CA  . ILE C 2 277 ? 115.314 123.072 99.816  1.00 81.94  ? 221 ILE R CA  1 
ATOM 2409 C C   . ILE C 2 277 ? 114.872 122.840 101.256 1.00 81.94  ? 221 ILE R C   1 
ATOM 2410 O O   . ILE C 2 277 ? 114.181 123.676 101.850 1.00 81.94  ? 221 ILE R O   1 
ATOM 2411 C CB  . ILE C 2 277 ? 114.541 122.171 98.837  1.00 77.71  ? 221 ILE R CB  1 
ATOM 2412 C CG1 . ILE C 2 277 ? 114.844 122.575 97.393  1.00 77.71  ? 221 ILE R CG1 1 
ATOM 2413 C CG2 . ILE C 2 277 ? 113.047 122.255 99.104  1.00 77.71  ? 221 ILE R CG2 1 
ATOM 2414 C CD1 . ILE C 2 277 ? 114.512 121.504 96.378  1.00 77.71  ? 221 ILE R CD1 1 
ATOM 2415 N N   . VAL C 2 278 ? 115.258 121.710 101.838 1.00 81.94  ? 222 VAL R N   1 
ATOM 2416 C CA  . VAL C 2 278 ? 114.825 121.370 103.190 1.00 81.94  ? 222 VAL R CA  1 
ATOM 2417 C C   . VAL C 2 278 ? 115.370 122.406 104.168 1.00 81.94  ? 222 VAL R C   1 
ATOM 2418 O O   . VAL C 2 278 ? 114.599 122.952 104.970 1.00 81.94  ? 222 VAL R O   1 
ATOM 2419 C CB  . VAL C 2 278 ? 115.252 119.943 103.572 1.00 77.11  ? 222 VAL R CB  1 
ATOM 2420 C CG1 . VAL C 2 278 ? 115.294 119.778 105.084 1.00 77.11  ? 222 VAL R CG1 1 
ATOM 2421 C CG2 . VAL C 2 278 ? 114.298 118.931 102.959 1.00 77.11  ? 222 VAL R CG2 1 
ATOM 2422 N N   . PRO C 2 279 ? 116.671 122.712 104.153 1.00 81.94  ? 223 PRO R N   1 
ATOM 2423 C CA  . PRO C 2 279 ? 117.160 123.779 105.043 1.00 81.94  ? 223 PRO R CA  1 
ATOM 2424 C C   . PRO C 2 279 ? 116.501 125.122 104.790 1.00 81.94  ? 223 PRO R C   1 
ATOM 2425 O O   . PRO C 2 279 ? 116.234 125.865 105.742 1.00 81.94  ? 223 PRO R O   1 
ATOM 2426 C CB  . PRO C 2 279 ? 118.665 123.815 104.741 1.00 76.23  ? 223 PRO R CB  1 
ATOM 2427 C CG  . PRO C 2 279 ? 118.972 122.452 104.247 1.00 76.23  ? 223 PRO R CG  1 
ATOM 2428 C CD  . PRO C 2 279 ? 117.780 122.074 103.426 1.00 76.23  ? 223 PRO R CD  1 
ATOM 2429 N N   . LEU C 2 280 ? 116.230 125.458 103.527 1.00 81.94  ? 224 LEU R N   1 
ATOM 2430 C CA  . LEU C 2 280 ? 115.619 126.749 103.226 1.00 81.94  ? 224 LEU R CA  1 
ATOM 2431 C C   . LEU C 2 280 ? 114.205 126.834 103.783 1.00 81.94  ? 224 LEU R C   1 
ATOM 2432 O O   . LEU C 2 280 ? 113.829 127.844 104.390 1.00 81.94  ? 224 LEU R O   1 
ATOM 2433 C CB  . LEU C 2 280 ? 115.615 126.986 101.716 1.00 73.37  ? 224 LEU R CB  1 
ATOM 2434 C CG  . LEU C 2 280 ? 115.076 128.340 101.251 1.00 73.37  ? 224 LEU R CG  1 
ATOM 2435 C CD1 . LEU C 2 280 ? 116.007 129.465 101.670 1.00 73.37  ? 224 LEU R CD1 1 
ATOM 2436 C CD2 . LEU C 2 280 ? 114.878 128.339 99.744  1.00 73.37  ? 224 LEU R CD2 1 
ATOM 2437 N N   . LEU C 2 281 ? 113.404 125.785 103.589 1.00 81.94  ? 225 LEU R N   1 
ATOM 2438 C CA  . LEU C 2 281 ? 112.033 125.809 104.085 1.00 81.94  ? 225 LEU R CA  1 
ATOM 2439 C C   . LEU C 2 281 ? 112.001 125.886 105.605 1.00 81.94  ? 225 LEU R C   1 
ATOM 2440 O O   . LEU C 2 281 ? 111.175 126.605 106.178 1.00 81.94  ? 225 LEU R O   1 
ATOM 2441 C CB  . LEU C 2 281 ? 111.275 124.576 103.593 1.00 81.94  ? 225 LEU R CB  1 
ATOM 2442 C CG  . LEU C 2 281 ? 110.980 124.484 102.092 1.00 81.94  ? 225 LEU R CG  1 
ATOM 2443 C CD1 . LEU C 2 281 ? 109.944 123.403 101.832 1.00 81.94  ? 225 LEU R CD1 1 
ATOM 2444 C CD2 . LEU C 2 281 ? 110.513 125.816 101.521 1.00 81.94  ? 225 LEU R CD2 1 
ATOM 2445 N N   . ILE C 2 282 ? 112.888 125.152 106.276 1.00 81.94  ? 226 ILE R N   1 
ATOM 2446 C CA  . ILE C 2 282 ? 112.939 125.204 107.734 1.00 81.94  ? 226 ILE R CA  1 
ATOM 2447 C C   . ILE C 2 282 ? 113.338 126.599 108.198 1.00 81.94  ? 226 ILE R C   1 
ATOM 2448 O O   . ILE C 2 282 ? 112.750 127.152 109.134 1.00 81.94  ? 226 ILE R O   1 
ATOM 2449 C CB  . ILE C 2 282 ? 113.901 124.132 108.276 1.00 64.66  ? 226 ILE R CB  1 
ATOM 2450 C CG1 . ILE C 2 282 ? 113.364 122.734 107.963 1.00 64.66  ? 226 ILE R CG1 1 
ATOM 2451 C CG2 . ILE C 2 282 ? 114.098 124.308 109.775 1.00 64.66  ? 226 ILE R CG2 1 
ATOM 2452 C CD1 . ILE C 2 282 ? 114.362 121.622 108.208 1.00 64.66  ? 226 ILE R CD1 1 
ATOM 2453 N N   . MET C 2 283 ? 114.346 127.188 107.552 1.00 81.94  ? 227 MET R N   1 
ATOM 2454 C CA  . MET C 2 283 ? 114.797 128.517 107.951 1.00 81.94  ? 227 MET R CA  1 
ATOM 2455 C C   . MET C 2 283 ? 113.713 129.561 107.723 1.00 81.94  ? 227 MET R C   1 
ATOM 2456 O O   . MET C 2 283 ? 113.461 130.405 108.592 1.00 81.94  ? 227 MET R O   1 
ATOM 2457 C CB  . MET C 2 283 ? 116.065 128.890 107.184 1.00 64.07  ? 227 MET R CB  1 
ATOM 2458 C CG  . MET C 2 283 ? 117.310 128.168 107.666 1.00 64.07  ? 227 MET R CG  1 
ATOM 2459 S SD  . MET C 2 283 ? 118.740 128.472 106.614 1.00 64.07  ? 227 MET R SD  1 
ATOM 2460 C CE  . MET C 2 283 ? 119.134 130.159 107.066 1.00 64.07  ? 227 MET R CE  1 
ATOM 2461 N N   . LEU C 2 284 ? 113.058 129.523 106.561 1.00 81.94  ? 228 LEU R N   1 
ATOM 2462 C CA  . LEU C 2 284 ? 112.050 130.533 106.256 1.00 81.94  ? 228 LEU R CA  1 
ATOM 2463 C C   . LEU C 2 284 ? 110.832 130.391 107.160 1.00 81.94  ? 228 LEU R C   1 
ATOM 2464 O O   . LEU C 2 284 ? 110.289 131.394 107.639 1.00 81.94  ? 228 LEU R O   1 
ATOM 2465 C CB  . LEU C 2 284 ? 111.643 130.439 104.787 1.00 63.15  ? 228 LEU R CB  1 
ATOM 2466 C CG  . LEU C 2 284 ? 112.641 131.028 103.787 1.00 63.15  ? 228 LEU R CG  1 
ATOM 2467 C CD1 . LEU C 2 284 ? 112.232 130.685 102.366 1.00 63.15  ? 228 LEU R CD1 1 
ATOM 2468 C CD2 . LEU C 2 284 ? 112.763 132.534 103.959 1.00 63.15  ? 228 LEU R CD2 1 
ATOM 2469 N N   . PHE C 2 285 ? 110.385 129.159 107.404 1.00 81.94  ? 229 PHE R N   1 
ATOM 2470 C CA  . PHE C 2 285 ? 109.251 128.951 108.299 1.00 81.94  ? 229 PHE R CA  1 
ATOM 2471 C C   . PHE C 2 285 ? 109.555 129.479 109.694 1.00 81.94  ? 229 PHE R C   1 
ATOM 2472 O O   . PHE C 2 285 ? 108.762 130.228 110.276 1.00 81.94  ? 229 PHE R O   1 
ATOM 2473 C CB  . PHE C 2 285 ? 108.898 127.466 108.356 1.00 63.26  ? 229 PHE R CB  1 
ATOM 2474 C CG  . PHE C 2 285 ? 107.713 127.158 109.224 1.00 63.26  ? 229 PHE R CG  1 
ATOM 2475 C CD1 . PHE C 2 285 ? 106.465 127.676 108.927 1.00 63.26  ? 229 PHE R CD1 1 
ATOM 2476 C CD2 . PHE C 2 285 ? 107.849 126.353 110.341 1.00 63.26  ? 229 PHE R CD2 1 
ATOM 2477 C CE1 . PHE C 2 285 ? 105.375 127.393 109.726 1.00 63.26  ? 229 PHE R CE1 1 
ATOM 2478 C CE2 . PHE C 2 285 ? 106.763 126.068 111.143 1.00 63.26  ? 229 PHE R CE2 1 
ATOM 2479 C CZ  . PHE C 2 285 ? 105.525 126.589 110.835 1.00 63.26  ? 229 PHE R CZ  1 
ATOM 2480 N N   . CYS C 2 286 ? 110.706 129.096 110.249 1.00 81.94  ? 230 CYS R N   1 
ATOM 2481 C CA  . CYS C 2 286 ? 111.063 129.527 111.596 1.00 81.94  ? 230 CYS R CA  1 
ATOM 2482 C C   . CYS C 2 286 ? 111.229 131.039 111.662 1.00 81.94  ? 230 CYS R C   1 
ATOM 2483 O O   . CYS C 2 286 ? 110.624 131.705 112.509 1.00 81.94  ? 230 CYS R O   1 
ATOM 2484 C CB  . CYS C 2 286 ? 112.344 128.822 112.033 1.00 63.89  ? 230 CYS R CB  1 
ATOM 2485 S SG  . CYS C 2 286 ? 112.142 127.058 112.346 1.00 63.89  ? 230 CYS R SG  1 
ATOM 2486 N N   . TYR C 2 287 ? 112.047 131.602 110.771 1.00 81.94  ? 231 TYR R N   1 
ATOM 2487 C CA  . TYR C 2 287 ? 112.225 133.048 110.744 1.00 81.94  ? 231 TYR R CA  1 
ATOM 2488 C C   . TYR C 2 287 ? 110.997 133.766 110.206 1.00 81.94  ? 231 TYR R C   1 
ATOM 2489 O O   . TYR C 2 287 ? 110.824 134.958 110.478 1.00 81.94  ? 231 TYR R O   1 
ATOM 2490 C CB  . TYR C 2 287 ? 113.448 133.415 109.904 1.00 56.01  ? 231 TYR R CB  1 
ATOM 2491 C CG  . TYR C 2 287 ? 114.766 133.013 110.526 1.00 56.01  ? 231 TYR R CG  1 
ATOM 2492 C CD1 . TYR C 2 287 ? 115.080 133.373 111.829 1.00 56.01  ? 231 TYR R CD1 1 
ATOM 2493 C CD2 . TYR C 2 287 ? 115.697 132.278 109.809 1.00 56.01  ? 231 TYR R CD2 1 
ATOM 2494 C CE1 . TYR C 2 287 ? 116.283 133.011 112.399 1.00 56.01  ? 231 TYR R CE1 1 
ATOM 2495 C CE2 . TYR C 2 287 ? 116.902 131.911 110.372 1.00 56.01  ? 231 TYR R CE2 1 
ATOM 2496 C CZ  . TYR C 2 287 ? 117.190 132.280 111.666 1.00 56.01  ? 231 TYR R CZ  1 
ATOM 2497 O OH  . TYR C 2 287 ? 118.390 131.916 112.229 1.00 56.01  ? 231 TYR R OH  1 
ATOM 2498 N N   . GLY C 2 288 ? 110.147 133.076 109.446 1.00 81.94  ? 232 GLY R N   1 
ATOM 2499 C CA  . GLY C 2 288 ? 108.923 133.703 108.977 1.00 81.94  ? 232 GLY R CA  1 
ATOM 2500 C C   . GLY C 2 288 ? 107.970 134.016 110.114 1.00 81.94  ? 232 GLY R C   1 
ATOM 2501 O O   . GLY C 2 288 ? 107.333 135.073 110.135 1.00 81.94  ? 232 GLY R O   1 
ATOM 2502 N N   . PHE C 2 289 ? 107.857 133.098 111.076 1.00 81.94  ? 233 PHE R N   1 
ATOM 2503 C CA  . PHE C 2 289 ? 106.965 133.318 112.209 1.00 81.94  ? 233 PHE R CA  1 
ATOM 2504 C C   . PHE C 2 289 ? 107.657 134.102 113.316 1.00 81.94  ? 233 PHE R C   1 
ATOM 2505 O O   . PHE C 2 289 ? 107.012 134.878 114.030 1.00 81.94  ? 233 PHE R O   1 
ATOM 2506 C CB  . PHE C 2 289 ? 106.453 131.979 112.737 1.00 65.04  ? 233 PHE R CB  1 
ATOM 2507 C CG  . PHE C 2 289 ? 105.232 131.481 112.024 1.00 65.04  ? 233 PHE R CG  1 
ATOM 2508 C CD1 . PHE C 2 289 ? 105.259 131.247 110.661 1.00 65.04  ? 233 PHE R CD1 1 
ATOM 2509 C CD2 . PHE C 2 289 ? 104.056 131.252 112.714 1.00 65.04  ? 233 PHE R CD2 1 
ATOM 2510 C CE1 . PHE C 2 289 ? 104.136 130.792 110.001 1.00 65.04  ? 233 PHE R CE1 1 
ATOM 2511 C CE2 . PHE C 2 289 ? 102.930 130.796 112.059 1.00 65.04  ? 233 PHE R CE2 1 
ATOM 2512 C CZ  . PHE C 2 289 ? 102.970 130.566 110.701 1.00 65.04  ? 233 PHE R CZ  1 
ATOM 2513 N N   . THR C 2 290 ? 108.968 133.913 113.477 1.00 81.94  ? 234 THR R N   1 
ATOM 2514 C CA  . THR C 2 290 ? 109.699 134.675 114.484 1.00 81.94  ? 234 THR R CA  1 
ATOM 2515 C C   . THR C 2 290 ? 109.554 136.172 114.243 1.00 81.94  ? 234 THR R C   1 
ATOM 2516 O O   . THR C 2 290 ? 109.446 136.953 115.195 1.00 81.94  ? 234 THR R O   1 
ATOM 2517 C CB  . THR C 2 290 ? 111.173 134.275 114.483 1.00 51.89  ? 234 THR R CB  1 
ATOM 2518 O OG1 . THR C 2 290 ? 111.312 132.954 115.018 1.00 51.89  ? 234 THR R OG1 1 
ATOM 2519 C CG2 . THR C 2 290 ? 111.991 135.241 115.323 1.00 51.89  ? 234 THR R CG2 1 
ATOM 2520 N N   . LEU C 2 291 ? 109.552 136.590 112.976 1.00 81.94  ? 235 LEU R N   1 
ATOM 2521 C CA  . LEU C 2 291 ? 109.400 138.008 112.671 1.00 81.94  ? 235 LEU R CA  1 
ATOM 2522 C C   . LEU C 2 291 ? 107.979 138.488 112.922 1.00 81.94  ? 235 LEU R C   1 
ATOM 2523 O O   . LEU C 2 291 ? 107.743 139.698 113.009 1.00 81.94  ? 235 LEU R O   1 
ATOM 2524 C CB  . LEU C 2 291 ? 109.792 138.278 111.219 1.00 56.11  ? 235 LEU R CB  1 
ATOM 2525 C CG  . LEU C 2 291 ? 111.279 138.155 110.892 1.00 56.11  ? 235 LEU R CG  1 
ATOM 2526 C CD1 . LEU C 2 291 ? 111.479 138.073 109.390 1.00 56.11  ? 235 LEU R CD1 1 
ATOM 2527 C CD2 . LEU C 2 291 ? 112.055 139.320 111.475 1.00 56.11  ? 235 LEU R CD2 1 
ATOM 2528 N N   . ARG C 2 292 ? 107.020 137.568 113.033 1.00 81.94  ? 236 ARG R N   1 
ATOM 2529 C CA  . ARG C 2 292 ? 105.641 137.977 113.278 1.00 81.94  ? 236 ARG R CA  1 
ATOM 2530 C C   . ARG C 2 292 ? 105.441 138.377 114.735 1.00 81.94  ? 236 ARG R C   1 
ATOM 2531 O O   . ARG C 2 292 ? 104.703 139.325 115.027 1.00 81.94  ? 236 ARG R O   1 
ATOM 2532 C CB  . ARG C 2 292 ? 104.685 136.850 112.887 1.00 72.75  ? 236 ARG R CB  1 
ATOM 2533 C CG  . ARG C 2 292 ? 103.333 136.885 113.584 1.00 72.75  ? 236 ARG R CG  1 
ATOM 2534 C CD  . ARG C 2 292 ? 102.235 136.378 112.667 1.00 72.75  ? 236 ARG R CD  1 
ATOM 2535 N NE  . ARG C 2 292 ? 101.913 137.329 111.610 1.00 72.75  ? 236 ARG R NE  1 
ATOM 2536 C CZ  . ARG C 2 292 ? 100.818 137.279 110.863 1.00 72.75  ? 236 ARG R CZ  1 
ATOM 2537 N NH1 . ARG C 2 292 ? 99.913  136.328 111.026 1.00 72.75  ? 236 ARG R NH1 1 
ATOM 2538 N NH2 . ARG C 2 292 ? 100.628 138.204 109.928 1.00 72.75  ? 236 ARG R NH2 1 
ATOM 2539 N N   . THR C 2 293 ? 106.083 137.666 115.665 1.00 81.94  ? 237 THR R N   1 
ATOM 2540 C CA  . THR C 2 293 ? 105.985 138.037 117.073 1.00 81.94  ? 237 THR R CA  1 
ATOM 2541 C C   . THR C 2 293 ? 106.820 139.276 117.370 1.00 81.94  ? 237 THR R C   1 
ATOM 2542 O O   . THR C 2 293 ? 106.369 140.189 118.071 1.00 81.94  ? 237 THR R O   1 
ATOM 2543 C CB  . THR C 2 293 ? 106.427 136.873 117.960 1.00 66.33  ? 237 THR R CB  1 
ATOM 2544 O OG1 . THR C 2 293 ? 107.670 136.348 117.480 1.00 66.33  ? 237 THR R OG1 1 
ATOM 2545 C CG2 . THR C 2 293 ? 105.377 135.775 117.960 1.00 66.33  ? 237 THR R CG2 1 
ATOM 2546 N N   . LEU C 2 294 ? 108.045 139.327 116.843 1.00 81.94  ? 238 LEU R N   1 
ATOM 2547 C CA  . LEU C 2 294 ? 108.881 140.504 117.036 1.00 81.94  ? 238 LEU R CA  1 
ATOM 2548 C C   . LEU C 2 294 ? 108.257 141.750 116.426 1.00 81.94  ? 238 LEU R C   1 
ATOM 2549 O O   . LEU C 2 294 ? 108.459 142.849 116.950 1.00 81.94  ? 238 LEU R O   1 
ATOM 2550 C CB  . LEU C 2 294 ? 110.268 140.274 116.438 1.00 53.85  ? 238 LEU R CB  1 
ATOM 2551 C CG  . LEU C 2 294 ? 111.083 139.149 117.075 1.00 53.85  ? 238 LEU R CG  1 
ATOM 2552 C CD1 . LEU C 2 294 ? 112.284 138.809 116.211 1.00 53.85  ? 238 LEU R CD1 1 
ATOM 2553 C CD2 . LEU C 2 294 ? 111.519 139.523 118.479 1.00 53.85  ? 238 LEU R CD2 1 
ATOM 2554 N N   . PHE C 2 295 ? 107.508 141.605 115.335 1.00 81.94  ? 239 PHE R N   1 
ATOM 2555 C CA  . PHE C 2 295 ? 106.831 142.742 114.727 1.00 81.94  ? 239 PHE R CA  1 
ATOM 2556 C C   . PHE C 2 295 ? 105.663 143.236 115.569 1.00 81.94  ? 239 PHE R C   1 
ATOM 2557 O O   . PHE C 2 295 ? 105.148 144.330 115.311 1.00 81.94  ? 239 PHE R O   1 
ATOM 2558 C CB  . PHE C 2 295 ? 106.347 142.364 113.324 1.00 72.51  ? 239 PHE R CB  1 
ATOM 2559 C CG  . PHE C 2 295 ? 105.626 143.470 112.609 1.00 72.51  ? 239 PHE R CG  1 
ATOM 2560 C CD1 . PHE C 2 295 ? 106.327 144.396 111.856 1.00 72.51  ? 239 PHE R CD1 1 
ATOM 2561 C CD2 . PHE C 2 295 ? 104.247 143.575 112.676 1.00 72.51  ? 239 PHE R CD2 1 
ATOM 2562 C CE1 . PHE C 2 295 ? 105.667 145.414 111.194 1.00 72.51  ? 239 PHE R CE1 1 
ATOM 2563 C CE2 . PHE C 2 295 ? 103.582 144.590 112.015 1.00 72.51  ? 239 PHE R CE2 1 
ATOM 2564 C CZ  . PHE C 2 295 ? 104.293 145.510 111.273 1.00 72.51  ? 239 PHE R CZ  1 
ATOM 2565 N N   . LYS C 2 296 ? 105.246 142.467 116.574 1.00 79.60  ? 240 LYS R N   1 
ATOM 2566 C CA  . LYS C 2 296 ? 104.125 142.832 117.427 1.00 79.60  ? 240 LYS R CA  1 
ATOM 2567 C C   . LYS C 2 296 ? 104.531 143.110 118.866 1.00 79.60  ? 240 LYS R C   1 
ATOM 2568 O O   . LYS C 2 296 ? 103.768 143.758 119.591 1.00 79.60  ? 240 LYS R O   1 
ATOM 2569 C CB  . LYS C 2 296 ? 103.068 141.718 117.404 1.00 79.60  ? 240 LYS R CB  1 
ATOM 2570 C CG  . LYS C 2 296 ? 101.812 142.015 118.214 1.00 79.60  ? 240 LYS R CG  1 
ATOM 2571 C CD  . LYS C 2 296 ? 100.781 140.894 118.109 1.00 79.60  ? 240 LYS R CD  1 
ATOM 2572 C CE  . LYS C 2 296 ? 101.309 139.564 118.634 1.00 79.60  ? 240 LYS R CE  1 
ATOM 2573 N NZ  . LYS C 2 296 ? 100.312 138.470 118.480 1.00 79.60  ? 240 LYS R NZ  1 
ATOM 2574 N N   . ALA C 2 297 ? 105.703 142.652 119.296 1.00 67.49  ? 241 ALA R N   1 
ATOM 2575 C CA  . ALA C 2 297 ? 106.142 142.869 120.664 1.00 67.49  ? 241 ALA R CA  1 
ATOM 2576 C C   . ALA C 2 297 ? 106.465 144.343 120.892 1.00 67.49  ? 241 ALA R C   1 
ATOM 2577 O O   . ALA C 2 297 ? 106.580 145.136 119.954 1.00 67.49  ? 241 ALA R O   1 
ATOM 2578 C CB  . ALA C 2 297 ? 107.365 142.008 120.979 1.00 67.49  ? 241 ALA R CB  1 
ATOM 2579 N N   . HIS C 2 298 ? 106.611 144.705 122.167 1.00 79.42  ? 242 HIS R N   1 
ATOM 2580 C CA  . HIS C 2 298 ? 106.843 146.084 122.572 1.00 79.42  ? 242 HIS R CA  1 
ATOM 2581 C C   . HIS C 2 298 ? 108.205 146.283 123.231 1.00 79.42  ? 242 HIS R C   1 
ATOM 2582 O O   . HIS C 2 298 ? 108.306 147.013 124.222 1.00 79.42  ? 242 HIS R O   1 
ATOM 2583 C CB  . HIS C 2 298 ? 105.730 146.542 123.514 1.00 79.42  ? 242 HIS R CB  1 
ATOM 2584 C CG  . HIS C 2 298 ? 104.395 146.664 122.850 1.00 79.42  ? 242 HIS R CG  1 
ATOM 2585 N ND1 . HIS C 2 298 ? 104.216 147.335 121.660 1.00 79.42  ? 242 HIS R ND1 1 
ATOM 2586 C CD2 . HIS C 2 298 ? 103.175 146.198 123.208 1.00 79.42  ? 242 HIS R CD2 1 
ATOM 2587 C CE1 . HIS C 2 298 ? 102.942 147.279 121.314 1.00 79.42  ? 242 HIS R CE1 1 
ATOM 2588 N NE2 . HIS C 2 298 ? 102.289 146.594 122.236 1.00 79.42  ? 242 HIS R NE2 1 
ATOM 2589 N N   . MET C 2 299 ? 109.251 145.653 122.704 1.00 64.57  ? 243 MET R N   1 
ATOM 2590 C CA  . MET C 2 299 ? 110.584 145.826 123.254 1.00 64.57  ? 243 MET R CA  1 
ATOM 2591 C C   . MET C 2 299 ? 111.283 147.014 122.599 1.00 64.57  ? 243 MET R C   1 
ATOM 2592 O O   . MET C 2 299 ? 110.717 147.729 121.768 1.00 64.57  ? 243 MET R O   1 
ATOM 2593 C CB  . MET C 2 299 ? 111.421 144.561 123.063 1.00 64.57  ? 243 MET R CB  1 
ATOM 2594 C CG  . MET C 2 299 ? 110.662 143.259 123.252 1.00 64.57  ? 243 MET R CG  1 
ATOM 2595 S SD  . MET C 2 299 ? 111.643 141.827 122.776 1.00 64.57  ? 243 MET R SD  1 
ATOM 2596 C CE  . MET C 2 299 ? 111.697 142.026 120.998 1.00 64.57  ? 243 MET R CE  1 
ATOM 2597 N N   . GLY C 2 300 ? 112.538 147.219 122.992 1.00 64.22  ? 244 GLY R N   1 
ATOM 2598 C CA  . GLY C 2 300 ? 113.361 148.264 122.416 1.00 64.22  ? 244 GLY R CA  1 
ATOM 2599 C C   . GLY C 2 300 ? 114.401 147.707 121.468 1.00 64.22  ? 244 GLY R C   1 
ATOM 2600 O O   . GLY C 2 300 ? 114.858 148.400 120.554 1.00 64.22  ? 244 GLY R O   1 
ATOM 2601 N N   . GLN C 2 301 ? 114.784 146.451 121.679 1.00 81.94  ? 245 GLN R N   1 
ATOM 2602 C CA  . GLN C 2 301 ? 115.759 145.771 120.840 1.00 81.94  ? 245 GLN R CA  1 
ATOM 2603 C C   . GLN C 2 301 ? 115.114 145.014 119.687 1.00 81.94  ? 245 GLN R C   1 
ATOM 2604 O O   . GLN C 2 301 ? 115.821 144.333 118.939 1.00 81.94  ? 245 GLN R O   1 
ATOM 2605 C CB  . GLN C 2 301 ? 116.596 144.808 121.684 1.00 81.94  ? 245 GLN R CB  1 
ATOM 2606 C CG  . GLN C 2 301 ? 117.163 145.432 122.947 1.00 81.94  ? 245 GLN R CG  1 
ATOM 2607 C CD  . GLN C 2 301 ? 116.261 145.238 124.149 1.00 81.94  ? 245 GLN R CD  1 
ATOM 2608 O OE1 . GLN C 2 301 ? 116.203 144.153 124.727 1.00 81.94  ? 245 GLN R OE1 1 
ATOM 2609 N NE2 . GLN C 2 301 ? 115.550 146.292 124.531 1.00 81.94  ? 245 GLN R NE2 1 
ATOM 2610 N N   . LYS C 2 302 ? 113.791 145.111 119.531 1.00 81.94  ? 246 LYS R N   1 
ATOM 2611 C CA  . LYS C 2 302 ? 113.131 144.440 118.417 1.00 81.94  ? 246 LYS R CA  1 
ATOM 2612 C C   . LYS C 2 302 ? 113.693 144.897 117.080 1.00 81.94  ? 246 LYS R C   1 
ATOM 2613 O O   . LYS C 2 302 ? 113.768 144.105 116.134 1.00 81.94  ? 246 LYS R O   1 
ATOM 2614 C CB  . LYS C 2 302 ? 111.625 144.702 118.460 1.00 62.84  ? 246 LYS R CB  1 
ATOM 2615 C CG  . LYS C 2 302 ? 111.252 146.130 118.095 1.00 62.84  ? 246 LYS R CG  1 
ATOM 2616 C CD  . LYS C 2 302 ? 109.823 146.475 118.477 1.00 62.84  ? 246 LYS R CD  1 
ATOM 2617 C CE  . LYS C 2 302 ? 108.822 145.593 117.761 1.00 62.84  ? 246 LYS R CE  1 
ATOM 2618 N NZ  . LYS C 2 302 ? 107.550 146.319 117.499 1.00 62.84  ? 246 LYS R NZ  1 
ATOM 2619 N N   . HIS C 2 303 ? 114.092 146.167 116.980 1.00 81.94  ? 247 HIS R N   1 
ATOM 2620 C CA  . HIS C 2 303 ? 114.520 146.708 115.695 1.00 81.94  ? 247 HIS R CA  1 
ATOM 2621 C C   . HIS C 2 303 ? 115.818 146.060 115.230 1.00 81.94  ? 247 HIS R C   1 
ATOM 2622 O O   . HIS C 2 303 ? 115.941 145.656 114.069 1.00 81.94  ? 247 HIS R O   1 
ATOM 2623 C CB  . HIS C 2 303 ? 114.675 148.224 115.797 1.00 81.94  ? 247 HIS R CB  1 
ATOM 2624 C CG  . HIS C 2 303 ? 113.371 148.955 115.879 1.00 81.94  ? 247 HIS R CG  1 
ATOM 2625 N ND1 . HIS C 2 303 ? 112.737 149.216 117.074 1.00 81.94  ? 247 HIS R ND1 1 
ATOM 2626 C CD2 . HIS C 2 303 ? 112.575 149.468 114.911 1.00 81.94  ? 247 HIS R CD2 1 
ATOM 2627 C CE1 . HIS C 2 303 ? 111.611 149.865 116.840 1.00 81.94  ? 247 HIS R CE1 1 
ATOM 2628 N NE2 . HIS C 2 303 ? 111.489 150.031 115.535 1.00 81.94  ? 247 HIS R NE2 1 
ATOM 2629 N N   . ARG C 2 304 ? 116.799 145.946 116.126 1.00 81.94  ? 248 ARG R N   1 
ATOM 2630 C CA  . ARG C 2 304 ? 118.063 145.330 115.742 1.00 81.94  ? 248 ARG R CA  1 
ATOM 2631 C C   . ARG C 2 304 ? 117.908 143.838 115.488 1.00 81.94  ? 248 ARG R C   1 
ATOM 2632 O O   . ARG C 2 304 ? 118.592 143.285 114.621 1.00 81.94  ? 248 ARG R O   1 
ATOM 2633 C CB  . ARG C 2 304 ? 119.117 145.574 116.819 1.00 81.94  ? 248 ARG R CB  1 
ATOM 2634 C CG  . ARG C 2 304 ? 120.533 145.270 116.362 1.00 81.94  ? 248 ARG R CG  1 
ATOM 2635 C CD  . ARG C 2 304 ? 121.500 146.368 116.770 1.00 81.94  ? 248 ARG R CD  1 
ATOM 2636 N NE  . ARG C 2 304 ? 122.782 146.246 116.083 1.00 81.94  ? 248 ARG R NE  1 
ATOM 2637 C CZ  . ARG C 2 304 ? 123.919 145.862 116.652 1.00 81.94  ? 248 ARG R CZ  1 
ATOM 2638 N NH1 . ARG C 2 304 ? 123.981 145.535 117.933 1.00 81.94  ? 248 ARG R NH1 1 
ATOM 2639 N NH2 . ARG C 2 304 ? 125.024 145.802 115.913 1.00 81.94  ? 248 ARG R NH2 1 
ATOM 2640 N N   . ALA C 2 305 ? 117.023 143.170 116.231 1.00 81.94  ? 249 ALA R N   1 
ATOM 2641 C CA  . ALA C 2 305 ? 116.842 141.735 116.047 1.00 81.94  ? 249 ALA R CA  1 
ATOM 2642 C C   . ALA C 2 305 ? 116.338 141.420 114.645 1.00 81.94  ? 249 ALA R C   1 
ATOM 2643 O O   . ALA C 2 305 ? 116.841 140.503 113.985 1.00 81.94  ? 249 ALA R O   1 
ATOM 2644 C CB  . ALA C 2 305 ? 115.877 141.190 117.099 1.00 64.43  ? 249 ALA R CB  1 
ATOM 2645 N N   . MET C 2 306 ? 115.345 142.174 114.168 1.00 81.94  ? 250 MET R N   1 
ATOM 2646 C CA  . MET C 2 306 ? 114.801 141.914 112.839 1.00 81.94  ? 250 MET R CA  1 
ATOM 2647 C C   . MET C 2 306 ? 115.863 142.102 111.763 1.00 81.94  ? 250 MET R C   1 
ATOM 2648 O O   . MET C 2 306 ? 115.973 141.286 110.840 1.00 81.94  ? 250 MET R O   1 
ATOM 2649 C CB  . MET C 2 306 ? 113.606 142.827 112.572 1.00 81.94  ? 250 MET R CB  1 
ATOM 2650 C CG  . MET C 2 306 ? 112.456 142.643 113.541 1.00 81.94  ? 250 MET R CG  1 
ATOM 2651 S SD  . MET C 2 306 ? 111.306 144.028 113.513 1.00 81.94  ? 250 MET R SD  1 
ATOM 2652 C CE  . MET C 2 306 ? 110.003 143.358 112.485 1.00 81.94  ? 250 MET R CE  1 
ATOM 2653 N N   . ARG C 2 307 ? 116.656 143.170 111.863 1.00 81.94  ? 251 ARG R N   1 
ATOM 2654 C CA  . ARG C 2 307 ? 117.690 143.405 110.862 1.00 81.94  ? 251 ARG R CA  1 
ATOM 2655 C C   . ARG C 2 307 ? 118.733 142.297 110.868 1.00 81.94  ? 251 ARG R C   1 
ATOM 2656 O O   . ARG C 2 307 ? 119.299 141.976 109.818 1.00 81.94  ? 251 ARG R O   1 
ATOM 2657 C CB  . ARG C 2 307 ? 118.353 144.761 111.097 1.00 81.94  ? 251 ARG R CB  1 
ATOM 2658 C CG  . ARG C 2 307 ? 117.369 145.912 111.186 1.00 81.94  ? 251 ARG R CG  1 
ATOM 2659 C CD  . ARG C 2 307 ? 117.933 147.185 110.579 1.00 81.94  ? 251 ARG R CD  1 
ATOM 2660 N NE  . ARG C 2 307 ? 117.143 148.356 110.941 1.00 81.94  ? 251 ARG R NE  1 
ATOM 2661 C CZ  . ARG C 2 307 ? 115.901 148.581 110.534 1.00 81.94  ? 251 ARG R CZ  1 
ATOM 2662 N NH1 . ARG C 2 307 ? 115.272 147.741 109.729 1.00 81.94  ? 251 ARG R NH1 1 
ATOM 2663 N NH2 . ARG C 2 307 ? 115.274 149.679 110.945 1.00 81.94  ? 251 ARG R NH2 1 
ATOM 2664 N N   . VAL C 2 308 ? 119.005 141.707 112.033 1.00 81.94  ? 252 VAL R N   1 
ATOM 2665 C CA  . VAL C 2 308 ? 119.919 140.572 112.084 1.00 81.94  ? 252 VAL R CA  1 
ATOM 2666 C C   . VAL C 2 308 ? 119.281 139.351 111.437 1.00 81.94  ? 252 VAL R C   1 
ATOM 2667 O O   . VAL C 2 308 ? 119.940 138.600 110.710 1.00 81.94  ? 252 VAL R O   1 
ATOM 2668 C CB  . VAL C 2 308 ? 120.340 140.291 113.538 1.00 81.94  ? 252 VAL R CB  1 
ATOM 2669 C CG1 . VAL C 2 308 ? 120.996 138.924 113.649 1.00 81.94  ? 252 VAL R CG1 1 
ATOM 2670 C CG2 . VAL C 2 308 ? 121.279 141.376 114.034 1.00 81.94  ? 252 VAL R CG2 1 
ATOM 2671 N N   . ILE C 2 309 ? 117.989 139.132 111.689 1.00 81.94  ? 253 ILE R N   1 
ATOM 2672 C CA  . ILE C 2 309 ? 117.301 137.994 111.090 1.00 81.94  ? 253 ILE R CA  1 
ATOM 2673 C C   . ILE C 2 309 ? 117.284 138.121 109.573 1.00 81.94  ? 253 ILE R C   1 
ATOM 2674 O O   . ILE C 2 309 ? 117.542 137.150 108.852 1.00 81.94  ? 253 ILE R O   1 
ATOM 2675 C CB  . ILE C 2 309 ? 115.881 137.870 111.670 1.00 81.94  ? 253 ILE R CB  1 
ATOM 2676 C CG1 . ILE C 2 309 ? 115.934 137.186 113.037 1.00 81.94  ? 253 ILE R CG1 1 
ATOM 2677 C CG2 . ILE C 2 309 ? 114.975 137.101 110.713 1.00 81.94  ? 253 ILE R CG2 1 
ATOM 2678 C CD1 . ILE C 2 309 ? 114.629 137.223 113.799 1.00 81.94  ? 253 ILE R CD1 1 
ATOM 2679 N N   . PHE C 2 310 ? 116.980 139.316 109.061 1.00 81.94  ? 254 PHE R N   1 
ATOM 2680 C CA  . PHE C 2 310 ? 116.967 139.514 107.616 1.00 81.94  ? 254 PHE R CA  1 
ATOM 2681 C C   . PHE C 2 310 ? 118.343 139.265 107.015 1.00 81.94  ? 254 PHE R C   1 
ATOM 2682 O O   . PHE C 2 310 ? 118.464 138.631 105.961 1.00 81.94  ? 254 PHE R O   1 
ATOM 2683 C CB  . PHE C 2 310 ? 116.491 140.929 107.286 1.00 81.94  ? 254 PHE R CB  1 
ATOM 2684 C CG  . PHE C 2 310 ? 115.017 141.031 107.023 1.00 81.94  ? 254 PHE R CG  1 
ATOM 2685 C CD1 . PHE C 2 310 ? 114.429 140.309 105.999 1.00 81.94  ? 254 PHE R CD1 1 
ATOM 2686 C CD2 . PHE C 2 310 ? 114.218 141.854 107.799 1.00 81.94  ? 254 PHE R CD2 1 
ATOM 2687 C CE1 . PHE C 2 310 ? 113.074 140.404 105.755 1.00 81.94  ? 254 PHE R CE1 1 
ATOM 2688 C CE2 . PHE C 2 310 ? 112.862 141.952 107.559 1.00 81.94  ? 254 PHE R CE2 1 
ATOM 2689 C CZ  . PHE C 2 310 ? 112.290 141.227 106.536 1.00 81.94  ? 254 PHE R CZ  1 
ATOM 2690 N N   . ALA C 2 311 ? 119.395 139.756 107.673 1.00 81.94  ? 255 ALA R N   1 
ATOM 2691 C CA  . ALA C 2 311 ? 120.744 139.563 107.154 1.00 81.94  ? 255 ALA R CA  1 
ATOM 2692 C C   . ALA C 2 311 ? 121.098 138.084 107.076 1.00 81.94  ? 255 ALA R C   1 
ATOM 2693 O O   . ALA C 2 311 ? 121.736 137.643 106.113 1.00 81.94  ? 255 ALA R O   1 
ATOM 2694 C CB  . ALA C 2 311 ? 121.751 140.309 108.027 1.00 81.94  ? 255 ALA R CB  1 
ATOM 2695 N N   . VAL C 2 312 ? 120.697 137.303 108.079 1.00 81.94  ? 256 VAL R N   1 
ATOM 2696 C CA  . VAL C 2 312 ? 121.020 135.878 108.087 1.00 81.94  ? 256 VAL R CA  1 
ATOM 2697 C C   . VAL C 2 312 ? 120.383 135.185 106.889 1.00 81.94  ? 256 VAL R C   1 
ATOM 2698 O O   . VAL C 2 312 ? 121.015 134.365 106.213 1.00 81.94  ? 256 VAL R O   1 
ATOM 2699 C CB  . VAL C 2 312 ? 120.572 135.235 109.411 1.00 81.94  ? 256 VAL R CB  1 
ATOM 2700 C CG1 . VAL C 2 312 ? 120.669 133.720 109.324 1.00 81.94  ? 256 VAL R CG1 1 
ATOM 2701 C CG2 . VAL C 2 312 ? 121.404 135.760 110.568 1.00 81.94  ? 256 VAL R CG2 1 
ATOM 2702 N N   . VAL C 2 313 ? 119.116 135.500 106.613 1.00 81.94  ? 257 VAL R N   1 
ATOM 2703 C CA  . VAL C 2 313 ? 118.410 134.836 105.520 1.00 81.94  ? 257 VAL R CA  1 
ATOM 2704 C C   . VAL C 2 313 ? 119.021 135.215 104.178 1.00 81.94  ? 257 VAL R C   1 
ATOM 2705 O O   . VAL C 2 313 ? 119.294 134.350 103.337 1.00 81.94  ? 257 VAL R O   1 
ATOM 2706 C CB  . VAL C 2 313 ? 116.909 135.175 105.574 1.00 81.94  ? 257 VAL R CB  1 
ATOM 2707 C CG1 . VAL C 2 313 ? 116.204 134.670 104.325 1.00 81.94  ? 257 VAL R CG1 1 
ATOM 2708 C CG2 . VAL C 2 313 ? 116.280 134.582 106.822 1.00 81.94  ? 257 VAL R CG2 1 
ATOM 2709 N N   . LEU C 2 314 ? 119.248 136.511 103.952 1.00 81.94  ? 258 LEU R N   1 
ATOM 2710 C CA  . LEU C 2 314 ? 119.780 136.949 102.666 1.00 81.94  ? 258 LEU R CA  1 
ATOM 2711 C C   . LEU C 2 314 ? 121.163 136.365 102.411 1.00 81.94  ? 258 LEU R C   1 
ATOM 2712 O O   . LEU C 2 314 ? 121.468 135.946 101.289 1.00 81.94  ? 258 LEU R O   1 
ATOM 2713 C CB  . LEU C 2 314 ? 119.827 138.475 102.605 1.00 81.94  ? 258 LEU R CB  1 
ATOM 2714 C CG  . LEU C 2 314 ? 118.473 139.186 102.608 1.00 81.94  ? 258 LEU R CG  1 
ATOM 2715 C CD1 . LEU C 2 314 ? 118.663 140.690 102.704 1.00 81.94  ? 258 LEU R CD1 1 
ATOM 2716 C CD2 . LEU C 2 314 ? 117.666 138.826 101.371 1.00 81.94  ? 258 LEU R CD2 1 
ATOM 2717 N N   . ILE C 2 315 ? 122.015 136.329 103.436 1.00 81.94  ? 259 ILE R N   1 
ATOM 2718 C CA  . ILE C 2 315 ? 123.355 135.780 103.256 1.00 81.94  ? 259 ILE R CA  1 
ATOM 2719 C C   . ILE C 2 315 ? 123.277 134.317 102.841 1.00 81.94  ? 259 ILE R C   1 
ATOM 2720 O O   . ILE C 2 315 ? 124.062 133.851 102.007 1.00 81.94  ? 259 ILE R O   1 
ATOM 2721 C CB  . ILE C 2 315 ? 124.182 135.962 104.541 1.00 81.94  ? 259 ILE R CB  1 
ATOM 2722 C CG1 . ILE C 2 315 ? 124.499 137.443 104.762 1.00 81.94  ? 259 ILE R CG1 1 
ATOM 2723 C CG2 . ILE C 2 315 ? 125.463 135.145 104.469 1.00 81.94  ? 259 ILE R CG2 1 
ATOM 2724 C CD1 . ILE C 2 315 ? 125.601 137.978 103.874 1.00 81.94  ? 259 ILE R CD1 1 
ATOM 2725 N N   . PHE C 2 316 ? 122.334 133.569 103.415 1.00 81.94  ? 260 PHE R N   1 
ATOM 2726 C CA  . PHE C 2 316 ? 122.161 132.173 103.028 1.00 81.94  ? 260 PHE R CA  1 
ATOM 2727 C C   . PHE C 2 316 ? 121.714 132.059 101.576 1.00 81.94  ? 260 PHE R C   1 
ATOM 2728 O O   . PHE C 2 316 ? 122.282 131.282 100.800 1.00 81.94  ? 260 PHE R O   1 
ATOM 2729 C CB  . PHE C 2 316 ? 121.155 131.497 103.961 1.00 81.94  ? 260 PHE R CB  1 
ATOM 2730 C CG  . PHE C 2 316 ? 120.826 130.081 103.582 1.00 81.94  ? 260 PHE R CG  1 
ATOM 2731 C CD1 . PHE C 2 316 ? 119.823 129.808 102.668 1.00 81.94  ? 260 PHE R CD1 1 
ATOM 2732 C CD2 . PHE C 2 316 ? 121.522 129.023 104.139 1.00 81.94  ? 260 PHE R CD2 1 
ATOM 2733 C CE1 . PHE C 2 316 ? 119.521 128.509 102.319 1.00 81.94  ? 260 PHE R CE1 1 
ATOM 2734 C CE2 . PHE C 2 316 ? 121.223 127.722 103.793 1.00 81.94  ? 260 PHE R CE2 1 
ATOM 2735 C CZ  . PHE C 2 316 ? 120.221 127.465 102.882 1.00 81.94  ? 260 PHE R CZ  1 
ATOM 2736 N N   . LEU C 2 317 ? 120.696 132.829 101.188 1.00 81.94  ? 261 LEU R N   1 
ATOM 2737 C CA  . LEU C 2 317 ? 120.203 132.770 99.816  1.00 81.94  ? 261 LEU R CA  1 
ATOM 2738 C C   . LEU C 2 317 ? 121.280 133.204 98.829  1.00 81.94  ? 261 LEU R C   1 
ATOM 2739 O O   . LEU C 2 317 ? 121.472 132.574 97.783  1.00 81.94  ? 261 LEU R O   1 
ATOM 2740 C CB  . LEU C 2 317 ? 118.958 133.646 99.669  1.00 81.94  ? 261 LEU R CB  1 
ATOM 2741 C CG  . LEU C 2 317 ? 117.635 133.064 100.171 1.00 81.94  ? 261 LEU R CG  1 
ATOM 2742 C CD1 . LEU C 2 317 ? 116.508 134.063 99.967  1.00 81.94  ? 261 LEU R CD1 1 
ATOM 2743 C CD2 . LEU C 2 317 ? 117.314 131.755 99.472  1.00 81.94  ? 261 LEU R CD2 1 
ATOM 2744 N N   . LEU C 2 318 ? 121.999 134.280 99.150  1.00 81.94  ? 262 LEU R N   1 
ATOM 2745 C CA  . LEU C 2 318 ? 123.005 134.798 98.228  1.00 81.94  ? 262 LEU R CA  1 
ATOM 2746 C C   . LEU C 2 318 ? 124.112 133.780 97.988  1.00 81.94  ? 262 LEU R C   1 
ATOM 2747 O O   . LEU C 2 318 ? 124.576 133.611 96.855  1.00 81.94  ? 262 LEU R O   1 
ATOM 2748 C CB  . LEU C 2 318 ? 123.586 136.101 98.776  1.00 81.94  ? 262 LEU R CB  1 
ATOM 2749 C CG  . LEU C 2 318 ? 124.629 136.801 97.903  1.00 81.94  ? 262 LEU R CG  1 
ATOM 2750 C CD1 . LEU C 2 318 ? 123.973 137.437 96.688  1.00 81.94  ? 262 LEU R CD1 1 
ATOM 2751 C CD2 . LEU C 2 318 ? 125.387 137.839 98.714  1.00 81.94  ? 262 LEU R CD2 1 
ATOM 2752 N N   . CYS C 2 319 ? 124.551 133.094 99.044  1.00 93.40  ? 263 CYS R N   1 
ATOM 2753 C CA  . CYS C 2 319 ? 125.685 132.185 98.920  1.00 93.40  ? 263 CYS R CA  1 
ATOM 2754 C C   . CYS C 2 319 ? 125.322 130.913 98.162  1.00 93.40  ? 263 CYS R C   1 
ATOM 2755 O O   . CYS C 2 319 ? 126.143 130.390 97.402  1.00 93.40  ? 263 CYS R O   1 
ATOM 2756 C CB  . CYS C 2 319 ? 126.224 131.833 100.306 1.00 93.40  ? 263 CYS R CB  1 
ATOM 2757 S SG  . CYS C 2 319 ? 127.463 132.989 100.932 1.00 93.40  ? 263 CYS R SG  1 
ATOM 2758 N N   . TRP C 2 320 ? 124.106 130.401 98.352  1.00 84.27  ? 264 TRP R N   1 
ATOM 2759 C CA  . TRP C 2 320 ? 123.741 129.082 97.850  1.00 84.27  ? 264 TRP R CA  1 
ATOM 2760 C C   . TRP C 2 320 ? 122.763 129.101 96.687  1.00 84.27  ? 264 TRP R C   1 
ATOM 2761 O O   . TRP C 2 320 ? 122.850 128.229 95.821  1.00 84.27  ? 264 TRP R O   1 
ATOM 2762 C CB  . TRP C 2 320 ? 123.140 128.238 98.980  1.00 84.27  ? 264 TRP R CB  1 
ATOM 2763 C CG  . TRP C 2 320 ? 124.134 127.885 100.039 1.00 84.27  ? 264 TRP R CG  1 
ATOM 2764 C CD1 . TRP C 2 320 ? 124.109 128.269 101.346 1.00 84.27  ? 264 TRP R CD1 1 
ATOM 2765 C CD2 . TRP C 2 320 ? 125.307 127.079 99.879  1.00 84.27  ? 264 TRP R CD2 1 
ATOM 2766 N NE1 . TRP C 2 320 ? 125.192 127.753 102.011 1.00 84.27  ? 264 TRP R NE1 1 
ATOM 2767 C CE2 . TRP C 2 320 ? 125.943 127.017 101.133 1.00 84.27  ? 264 TRP R CE2 1 
ATOM 2768 C CE3 . TRP C 2 320 ? 125.880 126.404 98.798  1.00 84.27  ? 264 TRP R CE3 1 
ATOM 2769 C CZ2 . TRP C 2 320 ? 127.123 126.306 101.336 1.00 84.27  ? 264 TRP R CZ2 1 
ATOM 2770 C CZ3 . TRP C 2 320 ? 127.051 125.699 99.002  1.00 84.27  ? 264 TRP R CZ3 1 
ATOM 2771 C CH2 . TRP C 2 320 ? 127.660 125.656 100.261 1.00 84.27  ? 264 TRP R CH2 1 
ATOM 2772 N N   . LEU C 2 321 ? 121.836 130.055 96.640  1.00 81.94  ? 265 LEU R N   1 
ATOM 2773 C CA  . LEU C 2 321 ? 120.854 130.053 95.560  1.00 81.94  ? 265 LEU R CA  1 
ATOM 2774 C C   . LEU C 2 321 ? 121.499 130.125 94.182  1.00 81.94  ? 265 LEU R C   1 
ATOM 2775 O O   . LEU C 2 321 ? 121.092 129.347 93.302  1.00 81.94  ? 265 LEU R O   1 
ATOM 2776 C CB  . LEU C 2 321 ? 119.857 131.202 95.756  1.00 81.94  ? 265 LEU R CB  1 
ATOM 2777 C CG  . LEU C 2 321 ? 118.744 131.312 94.711  1.00 81.94  ? 265 LEU R CG  1 
ATOM 2778 C CD1 . LEU C 2 321 ? 117.709 130.221 94.912  1.00 81.94  ? 265 LEU R CD1 1 
ATOM 2779 C CD2 . LEU C 2 321 ? 118.094 132.682 94.774  1.00 81.94  ? 265 LEU R CD2 1 
ATOM 2780 N N   . PRO C 2 322 ? 122.472 131.002 93.919  1.00 83.71  ? 266 PRO R N   1 
ATOM 2781 C CA  . PRO C 2 322 ? 123.085 131.004 92.579  1.00 83.71  ? 266 PRO R CA  1 
ATOM 2782 C C   . PRO C 2 322 ? 123.683 129.663 92.193  1.00 83.71  ? 266 PRO R C   1 
ATOM 2783 O O   . PRO C 2 322 ? 123.571 129.245 91.034  1.00 83.71  ? 266 PRO R O   1 
ATOM 2784 C CB  . PRO C 2 322 ? 124.152 132.101 92.700  1.00 83.71  ? 266 PRO R CB  1 
ATOM 2785 C CG  . PRO C 2 322 ? 123.624 133.005 93.756  1.00 83.71  ? 266 PRO R CG  1 
ATOM 2786 C CD  . PRO C 2 322 ? 123.034 132.067 94.765  1.00 83.71  ? 266 PRO R CD  1 
ATOM 2787 N N   . TYR C 2 323 ? 124.317 128.969 93.142  1.00 84.97  ? 267 TYR R N   1 
ATOM 2788 C CA  . TYR C 2 323 ? 124.935 127.686 92.826  1.00 84.97  ? 267 TYR R CA  1 
ATOM 2789 C C   . TYR C 2 323 ? 123.889 126.641 92.463  1.00 84.97  ? 267 TYR R C   1 
ATOM 2790 O O   . TYR C 2 323 ? 124.054 125.898 91.490  1.00 84.97  ? 267 TYR R O   1 
ATOM 2791 C CB  . TYR C 2 323 ? 125.779 127.209 94.007  1.00 84.97  ? 267 TYR R CB  1 
ATOM 2792 C CG  . TYR C 2 323 ? 126.414 125.854 93.797  1.00 84.97  ? 267 TYR R CG  1 
ATOM 2793 C CD1 . TYR C 2 323 ? 127.445 125.683 92.884  1.00 84.97  ? 267 TYR R CD1 1 
ATOM 2794 C CD2 . TYR C 2 323 ? 125.987 124.745 94.514  1.00 84.97  ? 267 TYR R CD2 1 
ATOM 2795 C CE1 . TYR C 2 323 ? 128.030 124.448 92.689  1.00 84.97  ? 267 TYR R CE1 1 
ATOM 2796 C CE2 . TYR C 2 323 ? 126.566 123.506 94.326  1.00 84.97  ? 267 TYR R CE2 1 
ATOM 2797 C CZ  . TYR C 2 323 ? 127.587 123.363 93.412  1.00 84.97  ? 267 TYR R CZ  1 
ATOM 2798 O OH  . TYR C 2 323 ? 128.168 122.130 93.220  1.00 84.97  ? 267 TYR R OH  1 
ATOM 2799 N N   . ASN C 2 324 ? 122.801 126.570 93.233  1.00 81.94  ? 268 ASN R N   1 
ATOM 2800 C CA  . ASN C 2 324 ? 121.778 125.565 92.966  1.00 81.94  ? 268 ASN R CA  1 
ATOM 2801 C C   . ASN C 2 324 ? 121.053 125.832 91.654  1.00 81.94  ? 268 ASN R C   1 
ATOM 2802 O O   . ASN C 2 324 ? 120.737 124.887 90.922  1.00 81.94  ? 268 ASN R O   1 
ATOM 2803 C CB  . ASN C 2 324 ? 120.781 125.511 94.122  1.00 81.94  ? 268 ASN R CB  1 
ATOM 2804 C CG  . ASN C 2 324 ? 121.214 124.561 95.220  1.00 81.94  ? 268 ASN R CG  1 
ATOM 2805 O OD1 . ASN C 2 324 ? 120.535 123.576 95.507  1.00 81.94  ? 268 ASN R OD1 1 
ATOM 2806 N ND2 . ASN C 2 324 ? 122.353 124.850 95.837  1.00 81.94  ? 268 ASN R ND2 1 
ATOM 2807 N N   . LEU C 2 325 ? 120.780 127.099 91.337  1.00 81.94  ? 269 LEU R N   1 
ATOM 2808 C CA  . LEU C 2 325 ? 120.112 127.407 90.078  1.00 81.94  ? 269 LEU R CA  1 
ATOM 2809 C C   . LEU C 2 325 ? 120.961 126.977 88.890  1.00 81.94  ? 269 LEU R C   1 
ATOM 2810 O O   . LEU C 2 325 ? 120.439 126.430 87.911  1.00 81.94  ? 269 LEU R O   1 
ATOM 2811 C CB  . LEU C 2 325 ? 119.800 128.901 89.998  1.00 81.94  ? 269 LEU R CB  1 
ATOM 2812 C CG  . LEU C 2 325 ? 118.617 129.404 90.829  1.00 81.94  ? 269 LEU R CG  1 
ATOM 2813 C CD1 . LEU C 2 325 ? 118.447 130.902 90.643  1.00 81.94  ? 269 LEU R CD1 1 
ATOM 2814 C CD2 . LEU C 2 325 ? 117.335 128.673 90.462  1.00 81.94  ? 269 LEU R CD2 1 
ATOM 2815 N N   . VAL C 2 326 ? 122.271 127.217 88.954  1.00 87.88  ? 270 VAL R N   1 
ATOM 2816 C CA  . VAL C 2 326 ? 123.160 126.746 87.899  1.00 87.88  ? 270 VAL R CA  1 
ATOM 2817 C C   . VAL C 2 326 ? 123.161 125.224 87.849  1.00 87.88  ? 270 VAL R C   1 
ATOM 2818 O O   . VAL C 2 326 ? 123.106 124.624 86.770  1.00 87.88  ? 270 VAL R O   1 
ATOM 2819 C CB  . VAL C 2 326 ? 124.577 127.307 88.107  1.00 87.88  ? 270 VAL R CB  1 
ATOM 2820 C CG1 . VAL C 2 326 ? 125.550 126.666 87.133  1.00 87.88  ? 270 VAL R CG1 1 
ATOM 2821 C CG2 . VAL C 2 326 ? 124.576 128.817 87.945  1.00 87.88  ? 270 VAL R CG2 1 
ATOM 2822 N N   . LEU C 2 327 ? 123.224 124.575 89.014  1.00 82.47  ? 271 LEU R N   1 
ATOM 2823 C CA  . LEU C 2 327 ? 123.214 123.117 89.048  1.00 82.47  ? 271 LEU R CA  1 
ATOM 2824 C C   . LEU C 2 327 ? 121.927 122.563 88.451  1.00 82.47  ? 271 LEU R C   1 
ATOM 2825 O O   . LEU C 2 327 ? 121.956 121.595 87.682  1.00 82.47  ? 271 LEU R O   1 
ATOM 2826 C CB  . LEU C 2 327 ? 123.394 122.626 90.484  1.00 82.47  ? 271 LEU R CB  1 
ATOM 2827 C CG  . LEU C 2 327 ? 124.284 121.396 90.658  1.00 82.47  ? 271 LEU R CG  1 
ATOM 2828 C CD1 . LEU C 2 327 ? 125.733 121.727 90.341  1.00 82.47  ? 271 LEU R CD1 1 
ATOM 2829 C CD2 . LEU C 2 327 ? 124.155 120.845 92.067  1.00 82.47  ? 271 LEU R CD2 1 
ATOM 2830 N N   . LEU C 2 328 ? 120.785 123.164 88.790  1.00 84.03  ? 272 LEU R N   1 
ATOM 2831 C CA  . LEU C 2 328 ? 119.527 122.739 88.188  1.00 84.03  ? 272 LEU R CA  1 
ATOM 2832 C C   . LEU C 2 328 ? 119.547 122.957 86.681  1.00 84.03  ? 272 LEU R C   1 
ATOM 2833 O O   . LEU C 2 328 ? 119.055 122.118 85.918  1.00 84.03  ? 272 LEU R O   1 
ATOM 2834 C CB  . LEU C 2 328 ? 118.359 123.490 88.827  1.00 84.03  ? 272 LEU R CB  1 
ATOM 2835 C CG  . LEU C 2 328 ? 116.990 123.308 88.166  1.00 84.03  ? 272 LEU R CG  1 
ATOM 2836 C CD1 . LEU C 2 328 ? 116.508 121.877 88.321  1.00 84.03  ? 272 LEU R CD1 1 
ATOM 2837 C CD2 . LEU C 2 328 ? 115.985 124.278 88.760  1.00 84.03  ? 272 LEU R CD2 1 
ATOM 2838 N N   . ALA C 2 329 ? 120.110 124.081 86.234  1.00 85.14  ? 273 ALA R N   1 
ATOM 2839 C CA  . ALA C 2 329 ? 120.218 124.329 84.801  1.00 85.14  ? 273 ALA R CA  1 
ATOM 2840 C C   . ALA C 2 329 ? 121.059 123.263 84.115  1.00 85.14  ? 273 ALA R C   1 
ATOM 2841 O O   . ALA C 2 329 ? 120.720 122.824 83.010  1.00 85.14  ? 273 ALA R O   1 
ATOM 2842 C CB  . ALA C 2 329 ? 120.811 125.715 84.551  1.00 85.14  ? 273 ALA R CB  1 
ATOM 2843 N N   . ASP C 2 330 ? 122.154 122.836 84.747  1.00 91.39  ? 274 ASP R N   1 
ATOM 2844 C CA  . ASP C 2 330 ? 122.973 121.776 84.169  1.00 91.39  ? 274 ASP R CA  1 
ATOM 2845 C C   . ASP C 2 330 ? 122.179 120.483 84.033  1.00 91.39  ? 274 ASP R C   1 
ATOM 2846 O O   . ASP C 2 330 ? 122.254 119.808 83.000  1.00 91.39  ? 274 ASP R O   1 
ATOM 2847 C CB  . ASP C 2 330 ? 124.217 121.553 85.029  1.00 91.39  ? 274 ASP R CB  1 
ATOM 2848 C CG  . ASP C 2 330 ? 125.197 120.585 84.399  1.00 91.39  ? 274 ASP R CG  1 
ATOM 2849 O OD1 . ASP C 2 330 ? 124.901 120.059 83.306  1.00 91.39  ? 274 ASP R OD1 1 
ATOM 2850 O OD2 . ASP C 2 330 ? 126.268 120.350 84.996  1.00 91.39  ? 274 ASP R OD2 1 
ATOM 2851 N N   . THR C 2 331 ? 121.412 120.122 85.063  1.00 87.01  ? 275 THR R N   1 
ATOM 2852 C CA  . THR C 2 331 ? 120.629 118.892 85.003  1.00 87.01  ? 275 THR R CA  1 
ATOM 2853 C C   . THR C 2 331 ? 119.590 118.955 83.892  1.00 87.01  ? 275 THR R C   1 
ATOM 2854 O O   . THR C 2 331 ? 119.379 117.972 83.172  1.00 87.01  ? 275 THR R O   1 
ATOM 2855 C CB  . THR C 2 331 ? 119.955 118.635 86.351  1.00 87.01  ? 275 THR R CB  1 
ATOM 2856 O OG1 . THR C 2 331 ? 120.952 118.346 87.339  1.00 87.01  ? 275 THR R OG1 1 
ATOM 2857 C CG2 . THR C 2 331 ? 118.987 117.466 86.254  1.00 87.01  ? 275 THR R CG2 1 
ATOM 2858 N N   . LEU C 2 332 ? 118.926 120.102 83.737  1.00 84.81  ? 276 LEU R N   1 
ATOM 2859 C CA  . LEU C 2 332 ? 117.919 120.233 82.691  1.00 84.81  ? 276 LEU R CA  1 
ATOM 2860 C C   . LEU C 2 332 ? 118.539 120.087 81.307  1.00 84.81  ? 276 LEU R C   1 
ATOM 2861 O O   . LEU C 2 332 ? 117.947 119.464 80.418  1.00 84.81  ? 276 LEU R O   1 
ATOM 2862 C CB  . LEU C 2 332 ? 117.204 121.577 82.818  1.00 84.81  ? 276 LEU R CB  1 
ATOM 2863 C CG  . LEU C 2 332 ? 116.156 121.654 83.928  1.00 84.81  ? 276 LEU R CG  1 
ATOM 2864 C CD1 . LEU C 2 332 ? 116.082 123.061 84.493  1.00 84.81  ? 276 LEU R CD1 1 
ATOM 2865 C CD2 . LEU C 2 332 ? 114.798 121.208 83.412  1.00 84.81  ? 276 LEU R CD2 1 
ATOM 2866 N N   . MET C 2 333 ? 119.726 120.659 81.104  1.00 96.74  ? 277 MET R N   1 
ATOM 2867 C CA  . MET C 2 333 ? 120.375 120.573 79.800  1.00 96.74  ? 277 MET R CA  1 
ATOM 2868 C C   . MET C 2 333 ? 120.718 119.131 79.445  1.00 96.74  ? 277 MET R C   1 
ATOM 2869 O O   . MET C 2 333 ? 120.524 118.706 78.301  1.00 96.74  ? 277 MET R O   1 
ATOM 2870 C CB  . MET C 2 333 ? 121.631 121.443 79.787  1.00 96.74  ? 277 MET R CB  1 
ATOM 2871 C CG  . MET C 2 333 ? 122.246 121.626 78.413  1.00 96.74  ? 277 MET R CG  1 
ATOM 2872 S SD  . MET C 2 333 ? 123.737 122.633 78.465  1.00 96.74  ? 277 MET R SD  1 
ATOM 2873 C CE  . MET C 2 333 ? 124.915 121.452 79.112  1.00 96.74  ? 277 MET R CE  1 
ATOM 2874 N N   . ARG C 2 334 ? 121.229 118.363 80.410  1.00 85.36  ? 278 ARG R N   1 
ATOM 2875 C CA  . ARG C 2 334 ? 121.600 116.980 80.132  1.00 85.36  ? 278 ARG R CA  1 
ATOM 2876 C C   . ARG C 2 334 ? 120.392 116.137 79.748  1.00 85.36  ? 278 ARG R C   1 
ATOM 2877 O O   . ARG C 2 334 ? 120.510 115.232 78.915  1.00 85.36  ? 278 ARG R O   1 
ATOM 2878 C CB  . ARG C 2 334 ? 122.298 116.367 81.344  1.00 85.36  ? 278 ARG R CB  1 
ATOM 2879 C CG  . ARG C 2 334 ? 123.731 116.821 81.530  1.00 85.36  ? 278 ARG R CG  1 
ATOM 2880 C CD  . ARG C 2 334 ? 124.444 115.961 82.555  1.00 85.36  ? 278 ARG R CD  1 
ATOM 2881 N NE  . ARG C 2 334 ? 125.665 116.592 83.044  1.00 85.36  ? 278 ARG R NE  1 
ATOM 2882 C CZ  . ARG C 2 334 ? 126.895 116.139 82.838  1.00 85.36  ? 278 ARG R CZ  1 
ATOM 2883 N NH1 . ARG C 2 334 ? 127.125 115.040 82.138  1.00 85.36  ? 278 ARG R NH1 1 
ATOM 2884 N NH2 . ARG C 2 334 ? 127.924 116.808 83.348  1.00 85.36  ? 278 ARG R NH2 1 
ATOM 2885 N N   . THR C 2 335 ? 119.232 116.413 80.338  1.00 92.09  ? 279 THR R N   1 
ATOM 2886 C CA  . THR C 2 335 ? 118.019 115.654 80.070  1.00 92.09  ? 279 THR R CA  1 
ATOM 2887 C C   . THR C 2 335 ? 117.323 116.087 78.786  1.00 92.09  ? 279 THR R C   1 
ATOM 2888 O O   . THR C 2 335 ? 116.244 115.571 78.479  1.00 92.09  ? 279 THR R O   1 
ATOM 2889 C CB  . THR C 2 335 ? 117.049 115.789 81.249  1.00 92.09  ? 279 THR R CB  1 
ATOM 2890 O OG1 . THR C 2 335 ? 117.773 115.685 82.480  1.00 92.09  ? 279 THR R OG1 1 
ATOM 2891 C CG2 . THR C 2 335 ? 115.986 114.700 81.202  1.00 92.09  ? 279 THR R CG2 1 
ATOM 2892 N N   . GLN C 2 336 ? 117.907 117.022 78.037  1.00 105.24 ? 280 GLN R N   1 
ATOM 2893 C CA  . GLN C 2 336 ? 117.370 117.544 76.784  1.00 105.24 ? 280 GLN R CA  1 
ATOM 2894 C C   . GLN C 2 336 ? 116.102 118.363 76.983  1.00 105.24 ? 280 GLN R C   1 
ATOM 2895 O O   . GLN C 2 336 ? 115.414 118.674 76.002  1.00 105.24 ? 280 GLN R O   1 
ATOM 2896 C CB  . GLN C 2 336 ? 117.097 116.425 75.771  1.00 105.24 ? 280 GLN R CB  1 
ATOM 2897 C CG  . GLN C 2 336 ? 118.354 115.805 75.183  1.00 105.24 ? 280 GLN R CG  1 
ATOM 2898 C CD  . GLN C 2 336 ? 119.154 116.788 74.351  1.00 105.24 ? 280 GLN R CD  1 
ATOM 2899 O OE1 . GLN C 2 336 ? 118.594 117.569 73.582  1.00 105.24 ? 280 GLN R OE1 1 
ATOM 2900 N NE2 . GLN C 2 336 ? 120.473 116.756 74.502  1.00 105.24 ? 280 GLN R NE2 1 
ATOM 2901 N N   . VAL C 2 337 ? 115.767 118.723 78.223  1.00 96.28  ? 281 VAL R N   1 
ATOM 2902 C CA  . VAL C 2 337 ? 114.638 119.619 78.452  1.00 96.28  ? 281 VAL R CA  1 
ATOM 2903 C C   . VAL C 2 337 ? 114.920 120.983 77.835  1.00 96.28  ? 281 VAL R C   1 
ATOM 2904 O O   . VAL C 2 337 ? 114.045 121.596 77.212  1.00 96.28  ? 281 VAL R O   1 
ATOM 2905 C CB  . VAL C 2 337 ? 114.337 119.729 79.957  1.00 96.28  ? 281 VAL R CB  1 
ATOM 2906 C CG1 . VAL C 2 337 ? 113.176 120.680 80.200  1.00 96.28  ? 281 VAL R CG1 1 
ATOM 2907 C CG2 . VAL C 2 337 ? 114.030 118.358 80.538  1.00 96.28  ? 281 VAL R CG2 1 
ATOM 2908 N N   . ILE C 2 338 ? 116.141 121.473 77.999  1.00 96.29  ? 282 ILE R N   1 
ATOM 2909 C CA  . ILE C 2 338 ? 116.588 122.716 77.387  1.00 96.29  ? 282 ILE R CA  1 
ATOM 2910 C C   . ILE C 2 338 ? 117.582 122.374 76.289  1.00 96.29  ? 282 ILE R C   1 
ATOM 2911 O O   . ILE C 2 338 ? 118.444 121.502 76.450  1.00 96.29  ? 282 ILE R O   1 
ATOM 2912 C CB  . ILE C 2 338 ? 117.211 123.665 78.433  1.00 96.29  ? 282 ILE R CB  1 
ATOM 2913 C CG1 . ILE C 2 338 ? 116.162 124.050 79.479  1.00 96.29  ? 282 ILE R CG1 1 
ATOM 2914 C CG2 . ILE C 2 338 ? 117.779 124.905 77.755  1.00 96.29  ? 282 ILE R CG2 1 
ATOM 2915 C CD1 . ILE C 2 338 ? 116.726 124.775 80.681  1.00 96.29  ? 282 ILE R CD1 1 
ATOM 2916 N N   . GLN C 2 339 ? 117.459 123.061 75.156  1.00 112.10 ? 283 GLN R N   1 
ATOM 2917 C CA  . GLN C 2 339 ? 118.298 122.756 74.007  1.00 112.10 ? 283 GLN R CA  1 
ATOM 2918 C C   . GLN C 2 339 ? 119.772 122.851 74.380  1.00 112.10 ? 283 GLN R C   1 
ATOM 2919 O O   . GLN C 2 339 ? 120.196 123.751 75.110  1.00 112.10 ? 283 GLN R O   1 
ATOM 2920 C CB  . GLN C 2 339 ? 117.988 123.710 72.853  1.00 112.10 ? 283 GLN R CB  1 
ATOM 2921 C CG  . GLN C 2 339 ? 118.513 123.241 71.506  1.00 112.10 ? 283 GLN R CG  1 
ATOM 2922 C CD  . GLN C 2 339 ? 118.743 124.386 70.538  1.00 112.10 ? 283 GLN R CD  1 
ATOM 2923 O OE1 . GLN C 2 339 ? 118.398 125.533 70.821  1.00 112.10 ? 283 GLN R OE1 1 
ATOM 2924 N NE2 . GLN C 2 339 ? 119.330 124.078 69.388  1.00 112.10 ? 283 GLN R NE2 1 
ATOM 2925 N N   . GLU C 2 340 ? 120.554 121.904 73.872  1.00 109.36 ? 284 GLU R N   1 
ATOM 2926 C CA  . GLU C 2 340 ? 121.979 121.825 74.154  1.00 109.36 ? 284 GLU R CA  1 
ATOM 2927 C C   . GLU C 2 340 ? 122.779 122.310 72.953  1.00 109.36 ? 284 GLU R C   1 
ATOM 2928 O O   . GLU C 2 340 ? 122.502 121.929 71.812  1.00 109.36 ? 284 GLU R O   1 
ATOM 2929 C CB  . GLU C 2 340 ? 122.389 120.393 74.501  1.00 109.36 ? 284 GLU R CB  1 
ATOM 2930 C CG  . GLU C 2 340 ? 123.731 120.291 75.207  1.00 109.36 ? 284 GLU R CG  1 
ATOM 2931 C CD  . GLU C 2 340 ? 124.041 118.881 75.669  1.00 109.36 ? 284 GLU R CD  1 
ATOM 2932 O OE1 . GLU C 2 340 ? 123.247 117.967 75.367  1.00 109.36 ? 284 GLU R OE1 1 
ATOM 2933 O OE2 . GLU C 2 340 ? 125.081 118.687 76.334  1.00 109.36 ? 284 GLU R OE2 1 
ATOM 2934 N N   . THR C 2 341 ? 123.773 123.153 73.220  1.00 105.82 ? 285 THR R N   1 
ATOM 2935 C CA  . THR C 2 341 ? 124.668 123.646 72.186  1.00 105.82 ? 285 THR R CA  1 
ATOM 2936 C C   . THR C 2 341 ? 126.038 123.872 72.803  1.00 105.82 ? 285 THR R C   1 
ATOM 2937 O O   . THR C 2 341 ? 126.187 123.937 74.026  1.00 105.82 ? 285 THR R O   1 
ATOM 2938 C CB  . THR C 2 341 ? 124.153 124.944 71.550  1.00 105.82 ? 285 THR R CB  1 
ATOM 2939 O OG1 . THR C 2 341 ? 123.969 125.938 72.564  1.00 105.82 ? 285 THR R OG1 1 
ATOM 2940 C CG2 . THR C 2 341 ? 122.833 124.705 70.830  1.00 105.82 ? 285 THR R CG2 1 
ATOM 2941 N N   . CYS C 2 342 ? 127.047 123.989 71.938  1.00 114.21 ? 286 CYS R N   1 
ATOM 2942 C CA  . CYS C 2 342 ? 128.407 124.193 72.424  1.00 114.21 ? 286 CYS R CA  1 
ATOM 2943 C C   . CYS C 2 342 ? 128.510 125.473 73.245  1.00 114.21 ? 286 CYS R C   1 
ATOM 2944 O O   . CYS C 2 342 ? 129.195 125.505 74.274  1.00 114.21 ? 286 CYS R O   1 
ATOM 2945 C CB  . CYS C 2 342 ? 129.382 124.225 71.246  1.00 114.21 ? 286 CYS R CB  1 
ATOM 2946 S SG  . CYS C 2 342 ? 131.092 123.734 71.626  1.00 114.21 ? 286 CYS R SG  1 
ATOM 2947 N N   . GLU C 2 343 ? 127.835 126.538 72.808  1.00 105.65 ? 287 GLU R N   1 
ATOM 2948 C CA  . GLU C 2 343 ? 127.895 127.796 73.545  1.00 105.65 ? 287 GLU R CA  1 
ATOM 2949 C C   . GLU C 2 343 ? 127.294 127.653 74.938  1.00 105.65 ? 287 GLU R C   1 
ATOM 2950 O O   . GLU C 2 343 ? 127.869 128.140 75.918  1.00 105.65 ? 287 GLU R O   1 
ATOM 2951 C CB  . GLU C 2 343 ? 127.178 128.896 72.763  1.00 105.65 ? 287 GLU R CB  1 
ATOM 2952 C CG  . GLU C 2 343 ? 128.028 129.531 71.665  1.00 105.65 ? 287 GLU R CG  1 
ATOM 2953 C CD  . GLU C 2 343 ? 128.070 131.049 71.739  1.00 105.65 ? 287 GLU R CD  1 
ATOM 2954 O OE1 . GLU C 2 343 ? 127.215 131.647 72.426  1.00 105.65 ? 287 GLU R OE1 1 
ATOM 2955 O OE2 . GLU C 2 343 ? 128.965 131.647 71.106  1.00 105.65 ? 287 GLU R OE2 1 
ATOM 2956 N N   . ARG C 2 344 ? 126.142 126.988 75.051  1.00 104.38 ? 288 ARG R N   1 
ATOM 2957 C CA  . ARG C 2 344 ? 125.502 126.848 76.356  1.00 104.38 ? 288 ARG R CA  1 
ATOM 2958 C C   . ARG C 2 344 ? 126.376 126.055 77.318  1.00 104.38 ? 288 ARG R C   1 
ATOM 2959 O O   . ARG C 2 344 ? 126.515 126.426 78.489  1.00 104.38 ? 288 ARG R O   1 
ATOM 2960 C CB  . ARG C 2 344 ? 124.134 126.185 76.206  1.00 104.38 ? 288 ARG R CB  1 
ATOM 2961 C CG  . ARG C 2 344 ? 123.085 127.076 75.567  1.00 104.38 ? 288 ARG R CG  1 
ATOM 2962 C CD  . ARG C 2 344 ? 121.701 126.800 76.137  1.00 104.38 ? 288 ARG R CD  1 
ATOM 2963 N NE  . ARG C 2 344 ? 120.646 127.419 75.343  1.00 104.38 ? 288 ARG R NE  1 
ATOM 2964 C CZ  . ARG C 2 344 ? 120.498 128.726 75.173  1.00 104.38 ? 288 ARG R CZ  1 
ATOM 2965 N NH1 . ARG C 2 344 ? 121.292 129.599 75.772  1.00 104.38 ? 288 ARG R NH1 1 
ATOM 2966 N NH2 . ARG C 2 344 ? 119.521 129.171 74.387  1.00 104.38 ? 288 ARG R NH2 1 
ATOM 2967 N N   . ARG C 2 345 ? 126.973 124.960 76.846  1.00 95.65  ? 289 ARG R N   1 
ATOM 2968 C CA  . ARG C 2 345 ? 127.852 124.180 77.710  1.00 95.65  ? 289 ARG R CA  1 
ATOM 2969 C C   . ARG C 2 345 ? 129.033 125.017 78.181  1.00 95.65  ? 289 ARG R C   1 
ATOM 2970 O O   . ARG C 2 345 ? 129.494 124.868 79.318  1.00 95.65  ? 289 ARG R O   1 
ATOM 2971 C CB  . ARG C 2 345 ? 128.334 122.929 76.977  1.00 95.65  ? 289 ARG R CB  1 
ATOM 2972 C CG  . ARG C 2 345 ? 127.224 121.946 76.639  1.00 95.65  ? 289 ARG R CG  1 
ATOM 2973 C CD  . ARG C 2 345 ? 127.560 121.120 75.410  1.00 95.65  ? 289 ARG R CD  1 
ATOM 2974 N NE  . ARG C 2 345 ? 128.776 120.335 75.600  1.00 95.65  ? 289 ARG R NE  1 
ATOM 2975 C CZ  . ARG C 2 345 ? 128.849 119.011 75.546  1.00 95.65  ? 289 ARG R CZ  1 
ATOM 2976 N NH1 . ARG C 2 345 ? 127.782 118.262 75.315  1.00 95.65  ? 289 ARG R NH1 1 
ATOM 2977 N NH2 . ARG C 2 345 ? 130.026 118.420 75.732  1.00 95.65  ? 289 ARG R NH2 1 
ATOM 2978 N N   . ASN C 2 346 ? 129.537 125.901 77.319  1.00 103.80 ? 290 ASN R N   1 
ATOM 2979 C CA  . ASN C 2 346 ? 130.615 126.795 77.725  1.00 103.80 ? 290 ASN R CA  1 
ATOM 2980 C C   . ASN C 2 346 ? 130.158 127.748 78.823  1.00 103.80 ? 290 ASN R C   1 
ATOM 2981 O O   . ASN C 2 346 ? 130.883 127.975 79.798  1.00 103.80 ? 290 ASN R O   1 
ATOM 2982 C CB  . ASN C 2 346 ? 131.126 127.579 76.517  1.00 103.80 ? 290 ASN R CB  1 
ATOM 2983 C CG  . ASN C 2 346 ? 132.637 127.615 76.441  1.00 103.80 ? 290 ASN R CG  1 
ATOM 2984 O OD1 . ASN C 2 346 ? 133.290 126.576 76.349  1.00 103.80 ? 290 ASN R OD1 1 
ATOM 2985 N ND2 . ASN C 2 346 ? 133.202 128.816 76.479  1.00 103.80 ? 290 ASN R ND2 1 
ATOM 2986 N N   . HIS C 2 347 ? 128.958 128.313 78.683  1.00 93.13  ? 291 HIS R N   1 
ATOM 2987 C CA  . HIS C 2 347 ? 128.473 129.278 79.665  1.00 93.13  ? 291 HIS R CA  1 
ATOM 2988 C C   . HIS C 2 347 ? 128.301 128.630 81.033  1.00 93.13  ? 291 HIS R C   1 
ATOM 2989 O O   . HIS C 2 347 ? 128.713 129.191 82.055  1.00 93.13  ? 291 HIS R O   1 
ATOM 2990 C CB  . HIS C 2 347 ? 127.153 129.885 79.188  1.00 93.13  ? 291 HIS R CB  1 
ATOM 2991 C CG  . HIS C 2 347 ? 127.301 130.811 78.021  1.00 93.13  ? 291 HIS R CG  1 
ATOM 2992 N ND1 . HIS C 2 347 ? 126.222 131.290 77.311  1.00 93.13  ? 291 HIS R ND1 1 
ATOM 2993 C CD2 . HIS C 2 347 ? 128.401 131.347 77.441  1.00 93.13  ? 291 HIS R CD2 1 
ATOM 2994 C CE1 . HIS C 2 347 ? 126.650 132.080 76.343  1.00 93.13  ? 291 HIS R CE1 1 
ATOM 2995 N NE2 . HIS C 2 347 ? 127.969 132.132 76.400  1.00 93.13  ? 291 HIS R NE2 1 
ATOM 2996 N N   . ILE C 2 348 ? 127.696 127.441 81.073  1.00 88.33  ? 292 ILE R N   1 
ATOM 2997 C CA  . ILE C 2 348 ? 127.443 126.790 82.353  1.00 88.33  ? 292 ILE R CA  1 
ATOM 2998 C C   . ILE C 2 348 ? 128.749 126.435 83.048  1.00 88.33  ? 292 ILE R C   1 
ATOM 2999 O O   . ILE C 2 348 ? 128.842 126.501 84.279  1.00 88.33  ? 292 ILE R O   1 
ATOM 3000 C CB  . ILE C 2 348 ? 126.554 125.548 82.156  1.00 88.33  ? 292 ILE R CB  1 
ATOM 3001 C CG1 . ILE C 2 348 ? 125.150 125.971 81.721  1.00 88.33  ? 292 ILE R CG1 1 
ATOM 3002 C CG2 . ILE C 2 348 ? 126.491 124.736 83.441  1.00 88.33  ? 292 ILE R CG2 1 
ATOM 3003 C CD1 . ILE C 2 348 ? 124.288 124.829 81.231  1.00 88.33  ? 292 ILE R CD1 1 
ATOM 3004 N N   . ASP C 2 349 ? 129.776 126.052 82.286  1.00 104.24 ? 293 ASP R N   1 
ATOM 3005 C CA  . ASP C 2 349 ? 131.051 125.700 82.902  1.00 104.24 ? 293 ASP R CA  1 
ATOM 3006 C C   . ASP C 2 349 ? 131.636 126.880 83.667  1.00 104.24 ? 293 ASP R C   1 
ATOM 3007 O O   . ASP C 2 349 ? 132.124 126.717 84.791  1.00 104.24 ? 293 ASP R O   1 
ATOM 3008 C CB  . ASP C 2 349 ? 132.032 125.215 81.835  1.00 104.24 ? 293 ASP R CB  1 
ATOM 3009 C CG  . ASP C 2 349 ? 131.699 123.827 81.324  1.00 104.24 ? 293 ASP R CG  1 
ATOM 3010 O OD1 . ASP C 2 349 ? 130.664 123.269 81.743  1.00 104.24 ? 293 ASP R OD1 1 
ATOM 3011 O OD2 . ASP C 2 349 ? 132.475 123.292 80.504  1.00 104.24 ? 293 ASP R OD2 1 
ATOM 3012 N N   . ARG C 2 350 ? 131.597 128.076 83.076  1.00 109.22 ? 294 ARG R N   1 
ATOM 3013 C CA  . ARG C 2 350 ? 132.077 129.259 83.782  1.00 109.22 ? 294 ARG R CA  1 
ATOM 3014 C C   . ARG C 2 350 ? 131.180 129.591 84.967  1.00 109.22 ? 294 ARG R C   1 
ATOM 3015 O O   . ARG C 2 350 ? 131.667 129.981 86.034  1.00 109.22 ? 294 ARG R O   1 
ATOM 3016 C CB  . ARG C 2 350 ? 132.157 130.446 82.823  1.00 109.22 ? 294 ARG R CB  1 
ATOM 3017 C CG  . ARG C 2 350 ? 133.060 130.211 81.625  1.00 109.22 ? 294 ARG R CG  1 
ATOM 3018 C CD  . ARG C 2 350 ? 133.258 131.483 80.818  1.00 109.22 ? 294 ARG R CD  1 
ATOM 3019 N NE  . ARG C 2 350 ? 134.055 131.251 79.619  1.00 109.22 ? 294 ARG R NE  1 
ATOM 3020 C CZ  . ARG C 2 350 ? 135.352 130.974 79.622  1.00 109.22 ? 294 ARG R CZ  1 
ATOM 3021 N NH1 . ARG C 2 350 ? 136.041 130.895 80.748  1.00 109.22 ? 294 ARG R NH1 1 
ATOM 3022 N NH2 . ARG C 2 350 ? 135.974 130.771 78.464  1.00 109.22 ? 294 ARG R NH2 1 
ATOM 3023 N N   . ALA C 2 351 ? 129.864 129.445 84.798  1.00 89.24  ? 295 ALA R N   1 
ATOM 3024 C CA  . ALA C 2 351 ? 128.941 129.767 85.881  1.00 89.24  ? 295 ALA R CA  1 
ATOM 3025 C C   . ALA C 2 351 ? 129.188 128.886 87.097  1.00 89.24  ? 295 ALA R C   1 
ATOM 3026 O O   . ALA C 2 351 ? 129.186 129.373 88.234  1.00 89.24  ? 295 ALA R O   1 
ATOM 3027 C CB  . ALA C 2 351 ? 127.499 129.624 85.400  1.00 89.24  ? 295 ALA R CB  1 
ATOM 3028 N N   . LEU C 2 352 ? 129.403 127.586 86.883  1.00 92.31  ? 296 LEU R N   1 
ATOM 3029 C CA  . LEU C 2 352 ? 129.648 126.689 88.006  1.00 92.31  ? 296 LEU R CA  1 
ATOM 3030 C C   . LEU C 2 352 ? 130.919 127.076 88.750  1.00 92.31  ? 296 LEU R C   1 
ATOM 3031 O O   . LEU C 2 352 ? 130.950 127.066 89.986  1.00 92.31  ? 296 LEU R O   1 
ATOM 3032 C CB  . LEU C 2 352 ? 129.738 125.245 87.516  1.00 92.31  ? 296 LEU R CB  1 
ATOM 3033 C CG  . LEU C 2 352 ? 128.410 124.504 87.355  1.00 92.31  ? 296 LEU R CG  1 
ATOM 3034 C CD1 . LEU C 2 352 ? 128.619 123.201 86.604  1.00 92.31  ? 296 LEU R CD1 1 
ATOM 3035 C CD2 . LEU C 2 352 ? 127.764 124.246 88.707  1.00 92.31  ? 296 LEU R CD2 1 
ATOM 3036 N N   . ASP C 2 353 ? 131.979 127.416 88.016  1.00 98.77  ? 297 ASP R N   1 
ATOM 3037 C CA  . ASP C 2 353 ? 133.225 127.809 88.664  1.00 98.77  ? 297 ASP R CA  1 
ATOM 3038 C C   . ASP C 2 353 ? 133.049 129.092 89.467  1.00 98.77  ? 297 ASP R C   1 
ATOM 3039 O O   . ASP C 2 353 ? 133.562 129.206 90.586  1.00 98.77  ? 297 ASP R O   1 
ATOM 3040 C CB  . ASP C 2 353 ? 134.326 127.979 87.618  1.00 98.77  ? 297 ASP R CB  1 
ATOM 3041 C CG  . ASP C 2 353 ? 135.694 128.175 88.238  1.00 98.77  ? 297 ASP R CG  1 
ATOM 3042 O OD1 . ASP C 2 353 ? 135.799 128.113 89.481  1.00 98.77  ? 297 ASP R OD1 1 
ATOM 3043 O OD2 . ASP C 2 353 ? 136.665 128.392 87.484  1.00 98.77  ? 297 ASP R OD2 1 
ATOM 3044 N N   . ALA C 2 354 ? 132.329 130.068 88.912  1.00 92.93  ? 298 ALA R N   1 
ATOM 3045 C CA  . ALA C 2 354 ? 132.155 131.343 89.600  1.00 92.93  ? 298 ALA R CA  1 
ATOM 3046 C C   . ALA C 2 354 ? 131.326 131.177 90.867  1.00 92.93  ? 298 ALA R C   1 
ATOM 3047 O O   . ALA C 2 354 ? 131.716 131.643 91.944  1.00 92.93  ? 298 ALA R O   1 
ATOM 3048 C CB  . ALA C 2 354 ? 131.502 132.357 88.660  1.00 92.93  ? 298 ALA R CB  1 
ATOM 3049 N N   . THR C 2 355 ? 130.175 130.511 90.759  1.00 88.87  ? 299 THR R N   1 
ATOM 3050 C CA  . THR C 2 355 ? 129.292 130.375 91.913  1.00 88.87  ? 299 THR R CA  1 
ATOM 3051 C C   . THR C 2 355 ? 129.957 129.586 93.033  1.00 88.87  ? 299 THR R C   1 
ATOM 3052 O O   . THR C 2 355 ? 129.824 129.940 94.210  1.00 88.87  ? 299 THR R O   1 
ATOM 3053 C CB  . THR C 2 355 ? 127.983 129.707 91.497  1.00 88.87  ? 299 THR R CB  1 
ATOM 3054 O OG1 . THR C 2 355 ? 128.266 128.483 90.808  1.00 88.87  ? 299 THR R OG1 1 
ATOM 3055 C CG2 . THR C 2 355 ? 127.181 130.625 90.588  1.00 88.87  ? 299 THR R CG2 1 
ATOM 3056 N N   . GLU C 2 356 ? 130.673 128.512 92.691  1.00 90.42  ? 300 GLU R N   1 
ATOM 3057 C CA  . GLU C 2 356 ? 131.331 127.710 93.718  1.00 90.42  ? 300 GLU R CA  1 
ATOM 3058 C C   . GLU C 2 356 ? 132.223 128.573 94.600  1.00 90.42  ? 300 GLU R C   1 
ATOM 3059 O O   . GLU C 2 356 ? 132.314 128.349 95.812  1.00 90.42  ? 300 GLU R O   1 
ATOM 3060 C CB  . GLU C 2 356 ? 132.141 126.588 93.070  1.00 90.42  ? 300 GLU R CB  1 
ATOM 3061 C CG  . GLU C 2 356 ? 131.316 125.364 92.703  1.00 90.42  ? 300 GLU R CG  1 
ATOM 3062 C CD  . GLU C 2 356 ? 132.174 124.181 92.300  1.00 90.42  ? 300 GLU R CD  1 
ATOM 3063 O OE1 . GLU C 2 356 ? 133.416 124.293 92.369  1.00 90.42  ? 300 GLU R OE1 1 
ATOM 3064 O OE2 . GLU C 2 356 ? 131.607 123.137 91.914  1.00 90.42  ? 300 GLU R OE2 1 
ATOM 3065 N N   . ILE C 2 357 ? 132.890 129.566 94.010  1.00 84.01  ? 301 ILE R N   1 
ATOM 3066 C CA  . ILE C 2 357 ? 133.672 130.507 94.806  1.00 84.01  ? 301 ILE R CA  1 
ATOM 3067 C C   . ILE C 2 357 ? 132.759 131.286 95.742  1.00 84.01  ? 301 ILE R C   1 
ATOM 3068 O O   . ILE C 2 357 ? 133.074 131.483 96.922  1.00 84.01  ? 301 ILE R O   1 
ATOM 3069 C CB  . ILE C 2 357 ? 134.475 131.449 93.890  1.00 84.01  ? 301 ILE R CB  1 
ATOM 3070 C CG1 . ILE C 2 357 ? 135.427 130.652 92.995  1.00 84.01  ? 301 ILE R CG1 1 
ATOM 3071 C CG2 . ILE C 2 357 ? 135.257 132.455 94.719  1.00 84.01  ? 301 ILE R CG2 1 
ATOM 3072 C CD1 . ILE C 2 357 ? 135.720 131.324 91.674  1.00 84.01  ? 301 ILE R CD1 1 
ATOM 3073 N N   . LEU C 2 358 ? 131.615 131.742 95.231  1.00 87.20  ? 302 LEU R N   1 
ATOM 3074 C CA  . LEU C 2 358 ? 130.683 132.503 96.056  1.00 87.20  ? 302 LEU R CA  1 
ATOM 3075 C C   . LEU C 2 358 ? 130.160 131.665 97.215  1.00 87.20  ? 302 LEU R C   1 
ATOM 3076 O O   . LEU C 2 358 ? 130.066 132.152 98.348  1.00 87.20  ? 302 LEU R O   1 
ATOM 3077 C CB  . LEU C 2 358 ? 129.527 133.010 95.194  1.00 87.20  ? 302 LEU R CB  1 
ATOM 3078 C CG  . LEU C 2 358 ? 128.514 133.932 95.874  1.00 87.20  ? 302 LEU R CG  1 
ATOM 3079 C CD1 . LEU C 2 358 ? 129.164 135.241 96.286  1.00 87.20  ? 302 LEU R CD1 1 
ATOM 3080 C CD2 . LEU C 2 358 ? 127.336 134.186 94.949  1.00 87.20  ? 302 LEU R CD2 1 
ATOM 3081 N N   . GLY C 2 359 ? 129.815 130.402 96.954  1.00 87.58  ? 303 GLY R N   1 
ATOM 3082 C CA  . GLY C 2 359 ? 129.282 129.555 98.007  1.00 87.58  ? 303 GLY R CA  1 
ATOM 3083 C C   . GLY C 2 359 ? 130.278 129.269 99.112  1.00 87.58  ? 303 GLY R C   1 
ATOM 3084 O O   . GLY C 2 359 ? 129.893 129.129 100.277 1.00 87.58  ? 303 GLY R O   1 
ATOM 3085 N N   . ILE C 2 360 ? 131.564 129.176 98.771  1.00 88.52  ? 304 ILE R N   1 
ATOM 3086 C CA  . ILE C 2 360 ? 132.591 128.849 99.747  1.00 88.52  ? 304 ILE R CA  1 
ATOM 3087 C C   . ILE C 2 360 ? 132.749 129.928 100.810 1.00 88.52  ? 304 ILE R C   1 
ATOM 3088 O O   . ILE C 2 360 ? 133.285 129.652 101.887 1.00 88.52  ? 304 ILE R O   1 
ATOM 3089 C CB  . ILE C 2 360 ? 133.928 128.589 99.016  1.00 88.52  ? 304 ILE R CB  1 
ATOM 3090 C CG1 . ILE C 2 360 ? 133.959 127.155 98.486  1.00 88.52  ? 304 ILE R CG1 1 
ATOM 3091 C CG2 . ILE C 2 360 ? 135.121 128.833 99.934  1.00 88.52  ? 304 ILE R CG2 1 
ATOM 3092 C CD1 . ILE C 2 360 ? 135.058 126.893 97.482  1.00 88.52  ? 304 ILE R CD1 1 
ATOM 3093 N N   . LEU C 2 361 ? 132.277 131.144 100.546 1.00 86.23  ? 305 LEU R N   1 
ATOM 3094 C CA  . LEU C 2 361 ? 132.415 132.242 101.494 1.00 86.23  ? 305 LEU R CA  1 
ATOM 3095 C C   . LEU C 2 361 ? 131.610 132.033 102.769 1.00 86.23  ? 305 LEU R C   1 
ATOM 3096 O O   . LEU C 2 361 ? 131.808 132.780 103.733 1.00 86.23  ? 305 LEU R O   1 
ATOM 3097 C CB  . LEU C 2 361 ? 131.991 133.559 100.838 1.00 86.23  ? 305 LEU R CB  1 
ATOM 3098 C CG  . LEU C 2 361 ? 132.817 134.022 99.636  1.00 86.23  ? 305 LEU R CG  1 
ATOM 3099 C CD1 . LEU C 2 361 ? 132.301 135.357 99.129  1.00 86.23  ? 305 LEU R CD1 1 
ATOM 3100 C CD2 . LEU C 2 361 ? 134.292 134.118 99.988  1.00 86.23  ? 305 LEU R CD2 1 
ATOM 3101 N N   . HIS C 2 362 ? 130.709 131.049 102.802 1.00 87.46  ? 306 HIS R N   1 
ATOM 3102 C CA  . HIS C 2 362 ? 129.918 130.816 104.005 1.00 87.46  ? 306 HIS R CA  1 
ATOM 3103 C C   . HIS C 2 362 ? 130.811 130.489 105.196 1.00 87.46  ? 306 HIS R C   1 
ATOM 3104 O O   . HIS C 2 362 ? 130.464 130.792 106.343 1.00 87.46  ? 306 HIS R O   1 
ATOM 3105 C CB  . HIS C 2 362 ? 128.911 129.692 103.758 1.00 87.46  ? 306 HIS R CB  1 
ATOM 3106 C CG  . HIS C 2 362 ? 129.492 128.316 103.876 1.00 87.46  ? 306 HIS R CG  1 
ATOM 3107 N ND1 . HIS C 2 362 ? 129.824 127.746 105.086 1.00 87.46  ? 306 HIS R ND1 1 
ATOM 3108 C CD2 . HIS C 2 362 ? 129.805 127.397 102.931 1.00 87.46  ? 306 HIS R CD2 1 
ATOM 3109 C CE1 . HIS C 2 362 ? 130.312 126.536 104.883 1.00 87.46  ? 306 HIS R CE1 1 
ATOM 3110 N NE2 . HIS C 2 362 ? 130.311 126.300 103.584 1.00 87.46  ? 306 HIS R NE2 1 
ATOM 3111 N N   . SER C 2 363 ? 131.966 129.871 104.944 1.00 82.87  ? 307 SER R N   1 
ATOM 3112 C CA  . SER C 2 363 ? 132.880 129.536 106.029 1.00 82.87  ? 307 SER R CA  1 
ATOM 3113 C C   . SER C 2 363 ? 133.532 130.770 106.636 1.00 82.87  ? 307 SER R C   1 
ATOM 3114 O O   . SER C 2 363 ? 134.156 130.666 107.698 1.00 82.87  ? 307 SER R O   1 
ATOM 3115 C CB  . SER C 2 363 ? 133.960 128.578 105.526 1.00 82.87  ? 307 SER R CB  1 
ATOM 3116 O OG  . SER C 2 363 ? 134.508 129.027 104.300 1.00 82.87  ? 307 SER R OG  1 
ATOM 3117 N N   . CYS C 2 364 ? 133.409 131.929 105.991 1.00 89.25  ? 308 CYS R N   1 
ATOM 3118 C CA  . CYS C 2 364 ? 134.016 133.164 106.472 1.00 89.25  ? 308 CYS R CA  1 
ATOM 3119 C C   . CYS C 2 364 ? 133.004 134.103 107.114 1.00 89.25  ? 308 CYS R C   1 
ATOM 3120 O O   . CYS C 2 364 ? 133.289 134.706 108.152 1.00 89.25  ? 308 CYS R O   1 
ATOM 3121 C CB  . CYS C 2 364 ? 134.723 133.880 105.318 1.00 89.25  ? 308 CYS R CB  1 
ATOM 3122 S SG  . CYS C 2 364 ? 136.458 133.436 105.146 1.00 89.25  ? 308 CYS R SG  1 
ATOM 3123 N N   . LEU C 2 365 ? 131.824 134.249 106.509 1.00 81.94  ? 309 LEU R N   1 
ATOM 3124 C CA  . LEU C 2 365 ? 130.829 135.162 107.056 1.00 81.94  ? 309 LEU R CA  1 
ATOM 3125 C C   . LEU C 2 365 ? 130.133 134.575 108.277 1.00 81.94  ? 309 LEU R C   1 
ATOM 3126 O O   . LEU C 2 365 ? 129.558 135.323 109.075 1.00 81.94  ? 309 LEU R O   1 
ATOM 3127 C CB  . LEU C 2 365 ? 129.800 135.516 105.982 1.00 81.94  ? 309 LEU R CB  1 
ATOM 3128 C CG  . LEU C 2 365 ? 130.319 136.292 104.767 1.00 81.94  ? 309 LEU R CG  1 
ATOM 3129 C CD1 . LEU C 2 365 ? 129.158 136.800 103.929 1.00 81.94  ? 309 LEU R CD1 1 
ATOM 3130 C CD2 . LEU C 2 365 ? 131.220 137.446 105.182 1.00 81.94  ? 309 LEU R CD2 1 
ATOM 3131 N N   . ASN C 2 366 ? 130.173 133.255 108.444 1.00 81.94  ? 310 ASN R N   1 
ATOM 3132 C CA  . ASN C 2 366 ? 129.465 132.623 109.556 1.00 81.94  ? 310 ASN R CA  1 
ATOM 3133 C C   . ASN C 2 366 ? 129.892 133.162 110.914 1.00 81.94  ? 310 ASN R C   1 
ATOM 3134 O O   . ASN C 2 366 ? 129.012 133.505 111.719 1.00 81.94  ? 310 ASN R O   1 
ATOM 3135 C CB  . ASN C 2 366 ? 129.666 131.103 109.488 1.00 81.94  ? 310 ASN R CB  1 
ATOM 3136 C CG  . ASN C 2 366 ? 128.527 130.393 108.782 1.00 81.94  ? 310 ASN R CG  1 
ATOM 3137 O OD1 . ASN C 2 366 ? 127.563 131.020 108.344 1.00 81.94  ? 310 ASN R OD1 1 
ATOM 3138 N ND2 . ASN C 2 366 ? 128.633 129.074 108.671 1.00 81.94  ? 310 ASN R ND2 1 
ATOM 3139 N N   . PRO C 2 367 ? 131.182 133.261 111.237 1.00 81.94  ? 311 PRO R N   1 
ATOM 3140 C CA  . PRO C 2 367 ? 131.559 133.863 112.526 1.00 81.94  ? 311 PRO R CA  1 
ATOM 3141 C C   . PRO C 2 367 ? 131.021 135.271 112.718 1.00 81.94  ? 311 PRO R C   1 
ATOM 3142 O O   . PRO C 2 367 ? 130.608 135.626 113.829 1.00 81.94  ? 311 PRO R O   1 
ATOM 3143 C CB  . PRO C 2 367 ? 133.091 133.844 112.474 1.00 81.94  ? 311 PRO R CB  1 
ATOM 3144 C CG  . PRO C 2 367 ? 133.414 132.684 111.612 1.00 81.94  ? 311 PRO R CG  1 
ATOM 3145 C CD  . PRO C 2 367 ? 132.337 132.642 110.564 1.00 81.94  ? 311 PRO R CD  1 
ATOM 3146 N N   . LEU C 2 368 ? 131.016 136.087 111.663 1.00 81.94  ? 312 LEU R N   1 
ATOM 3147 C CA  . LEU C 2 368 ? 130.525 137.454 111.787 1.00 81.94  ? 312 LEU R CA  1 
ATOM 3148 C C   . LEU C 2 368 ? 129.007 137.500 111.914 1.00 81.94  ? 312 LEU R C   1 
ATOM 3149 O O   . LEU C 2 368 ? 128.474 138.230 112.756 1.00 81.94  ? 312 LEU R O   1 
ATOM 3150 C CB  . LEU C 2 368 ? 130.973 138.284 110.584 1.00 81.94  ? 312 LEU R CB  1 
ATOM 3151 C CG  . LEU C 2 368 ? 132.438 138.149 110.165 1.00 81.94  ? 312 LEU R CG  1 
ATOM 3152 C CD1 . LEU C 2 368 ? 132.775 139.174 109.095 1.00 81.94  ? 312 LEU R CD1 1 
ATOM 3153 C CD2 . LEU C 2 368 ? 133.364 138.299 111.362 1.00 81.94  ? 312 LEU R CD2 1 
ATOM 3154 N N   . ILE C 2 369 ? 128.299 136.728 111.090 1.00 81.94  ? 313 ILE R N   1 
ATOM 3155 C CA  . ILE C 2 369 ? 126.845 136.835 111.040 1.00 81.94  ? 313 ILE R CA  1 
ATOM 3156 C C   . ILE C 2 369 ? 126.214 136.279 112.310 1.00 81.94  ? 313 ILE R C   1 
ATOM 3157 O O   . ILE C 2 369 ? 125.285 136.876 112.868 1.00 81.94  ? 313 ILE R O   1 
ATOM 3158 C CB  . ILE C 2 369 ? 126.306 136.126 109.785 1.00 81.94  ? 313 ILE R CB  1 
ATOM 3159 C CG1 . ILE C 2 369 ? 126.811 136.818 108.515 1.00 81.94  ? 313 ILE R CG1 1 
ATOM 3160 C CG2 . ILE C 2 369 ? 124.788 136.090 109.806 1.00 81.94  ? 313 ILE R CG2 1 
ATOM 3161 C CD1 . ILE C 2 369 ? 126.280 138.227 108.310 1.00 81.94  ? 313 ILE R CD1 1 
ATOM 3162 N N   . TYR C 2 370 ? 126.697 135.133 112.789 1.00 81.94  ? 314 TYR R N   1 
ATOM 3163 C CA  . TYR C 2 370 ? 126.038 134.441 113.890 1.00 81.94  ? 314 TYR R CA  1 
ATOM 3164 C C   . TYR C 2 370 ? 126.673 134.726 115.245 1.00 81.94  ? 314 TYR R C   1 
ATOM 3165 O O   . TYR C 2 370 ? 125.955 134.942 116.227 1.00 81.94  ? 314 TYR R O   1 
ATOM 3166 C CB  . TYR C 2 370 ? 126.043 132.932 113.636 1.00 81.94  ? 314 TYR R CB  1 
ATOM 3167 C CG  . TYR C 2 370 ? 125.044 132.492 112.595 1.00 81.94  ? 314 TYR R CG  1 
ATOM 3168 C CD1 . TYR C 2 370 ? 123.726 132.231 112.940 1.00 81.94  ? 314 TYR R CD1 1 
ATOM 3169 C CD2 . TYR C 2 370 ? 125.416 132.339 111.268 1.00 81.94  ? 314 TYR R CD2 1 
ATOM 3170 C CE1 . TYR C 2 370 ? 122.807 131.830 111.994 1.00 81.94  ? 314 TYR R CE1 1 
ATOM 3171 C CE2 . TYR C 2 370 ? 124.504 131.939 110.314 1.00 81.94  ? 314 TYR R CE2 1 
ATOM 3172 C CZ  . TYR C 2 370 ? 123.200 131.686 110.683 1.00 81.94  ? 314 TYR R CZ  1 
ATOM 3173 O OH  . TYR C 2 370 ? 122.287 131.286 109.737 1.00 81.94  ? 314 TYR R OH  1 
ATOM 3174 N N   . ALA C 2 371 ? 128.001 134.735 115.325 1.00 81.94  ? 315 ALA R N   1 
ATOM 3175 C CA  . ALA C 2 371 ? 128.701 134.803 116.601 1.00 81.94  ? 315 ALA R CA  1 
ATOM 3176 C C   . ALA C 2 371 ? 129.111 136.215 116.989 1.00 81.94  ? 315 ALA R C   1 
ATOM 3177 O O   . ALA C 2 371 ? 128.741 136.690 118.067 1.00 81.94  ? 315 ALA R O   1 
ATOM 3178 C CB  . ALA C 2 371 ? 129.941 133.899 116.560 1.00 81.94  ? 315 ALA R CB  1 
ATOM 3179 N N   . PHE C 2 372 ? 129.868 136.906 116.137 1.00 85.42  ? 316 PHE R N   1 
ATOM 3180 C CA  . PHE C 2 372 ? 130.430 138.197 116.517 1.00 85.42  ? 316 PHE R CA  1 
ATOM 3181 C C   . PHE C 2 372 ? 129.425 139.337 116.434 1.00 85.42  ? 316 PHE R C   1 
ATOM 3182 O O   . PHE C 2 372 ? 129.829 140.498 116.557 1.00 85.42  ? 316 PHE R O   1 
ATOM 3183 C CB  . PHE C 2 372 ? 131.640 138.517 115.638 1.00 85.42  ? 316 PHE R CB  1 
ATOM 3184 C CG  . PHE C 2 372 ? 132.891 137.791 116.042 1.00 85.42  ? 316 PHE R CG  1 
ATOM 3185 C CD1 . PHE C 2 372 ? 133.373 137.879 117.337 1.00 85.42  ? 316 PHE R CD1 1 
ATOM 3186 C CD2 . PHE C 2 372 ? 133.586 137.021 115.126 1.00 85.42  ? 316 PHE R CD2 1 
ATOM 3187 C CE1 . PHE C 2 372 ? 134.521 137.212 117.711 1.00 85.42  ? 316 PHE R CE1 1 
ATOM 3188 C CE2 . PHE C 2 372 ? 134.737 136.352 115.495 1.00 85.42  ? 316 PHE R CE2 1 
ATOM 3189 C CZ  . PHE C 2 372 ? 135.205 136.448 116.789 1.00 85.42  ? 316 PHE R CZ  1 
ATOM 3190 N N   . ILE C 2 373 ? 128.141 139.046 116.235 1.00 81.94  ? 317 ILE R N   1 
ATOM 3191 C CA  . ILE C 2 373 ? 127.124 140.090 116.180 1.00 81.94  ? 317 ILE R CA  1 
ATOM 3192 C C   . ILE C 2 373 ? 126.370 140.137 117.503 1.00 81.94  ? 317 ILE R C   1 
ATOM 3193 O O   . ILE C 2 373 ? 125.322 140.783 117.608 1.00 81.94  ? 317 ILE R O   1 
ATOM 3194 C CB  . ILE C 2 373 ? 126.161 139.863 115.001 1.00 81.94  ? 317 ILE R CB  1 
ATOM 3195 C CG1 . ILE C 2 373 ? 125.496 141.180 114.597 1.00 81.94  ? 317 ILE R CG1 1 
ATOM 3196 C CG2 . ILE C 2 373 ? 125.110 138.823 115.357 1.00 81.94  ? 317 ILE R CG2 1 
ATOM 3197 C CD1 . ILE C 2 373 ? 125.007 141.200 113.169 1.00 81.94  ? 317 ILE R CD1 1 
ATOM 3198 N N   . GLY C 2 374 ? 126.897 139.464 118.517 1.00 93.73  ? 318 GLY R N   1 
ATOM 3199 C CA  . GLY C 2 374 ? 126.258 139.395 119.823 1.00 93.73  ? 318 GLY R CA  1 
ATOM 3200 C C   . GLY C 2 374 ? 127.111 140.060 120.886 1.00 93.73  ? 318 GLY R C   1 
ATOM 3201 O O   . GLY C 2 374 ? 128.340 140.039 120.807 1.00 93.73  ? 318 GLY R O   1 
ATOM 3202 N N   . GLN C 2 375 ? 126.446 140.648 121.882 1.00 96.31  ? 319 GLN R N   1 
ATOM 3203 C CA  . GLN C 2 375 ? 127.164 141.364 122.932 1.00 96.31  ? 319 GLN R CA  1 
ATOM 3204 C C   . GLN C 2 375 ? 128.062 140.422 123.726 1.00 96.31  ? 319 GLN R C   1 
ATOM 3205 O O   . GLN C 2 375 ? 129.201 140.767 124.059 1.00 96.31  ? 319 GLN R O   1 
ATOM 3206 C CB  . GLN C 2 375 ? 126.172 142.066 123.859 1.00 96.31  ? 319 GLN R CB  1 
ATOM 3207 C CG  . GLN C 2 375 ? 126.813 143.081 124.792 1.00 96.31  ? 319 GLN R CG  1 
ATOM 3208 C CD  . GLN C 2 375 ? 125.852 143.598 125.844 1.00 96.31  ? 319 GLN R CD  1 
ATOM 3209 O OE1 . GLN C 2 375 ? 124.702 143.167 125.916 1.00 96.31  ? 319 GLN R OE1 1 
ATOM 3210 N NE2 . GLN C 2 375 ? 126.322 144.528 126.667 1.00 96.31  ? 319 GLN R NE2 1 
ATOM 3211 N N   . LYS C 2 376 ? 127.562 139.227 124.042 1.00 93.85  ? 320 LYS R N   1 
ATOM 3212 C CA  . LYS C 2 376 ? 128.317 138.310 124.890 1.00 93.85  ? 320 LYS R CA  1 
ATOM 3213 C C   . LYS C 2 376 ? 129.662 137.962 124.263 1.00 93.85  ? 320 LYS R C   1 
ATOM 3214 O O   . LYS C 2 376 ? 130.703 138.016 124.928 1.00 93.85  ? 320 LYS R O   1 
ATOM 3215 C CB  . LYS C 2 376 ? 127.498 137.045 125.148 1.00 93.85  ? 320 LYS R CB  1 
ATOM 3216 C CG  . LYS C 2 376 ? 127.783 136.394 126.495 1.00 93.85  ? 320 LYS R CG  1 
ATOM 3217 C CD  . LYS C 2 376 ? 126.934 135.150 126.728 1.00 93.85  ? 320 LYS R CD  1 
ATOM 3218 C CE  . LYS C 2 376 ? 125.447 135.470 126.762 1.00 93.85  ? 320 LYS R CE  1 
ATOM 3219 N NZ  . LYS C 2 376 ? 124.632 134.283 127.138 1.00 93.85  ? 320 LYS R NZ  1 
ATOM 3220 N N   . PHE C 2 377 ? 129.660 137.599 122.979 1.00 91.04  ? 321 PHE R N   1 
ATOM 3221 C CA  . PHE C 2 377 ? 130.913 137.251 122.317 1.00 91.04  ? 321 PHE R CA  1 
ATOM 3222 C C   . PHE C 2 377 ? 131.822 138.463 122.181 1.00 91.04  ? 321 PHE R C   1 
ATOM 3223 O O   . PHE C 2 377 ? 133.028 138.375 122.438 1.00 91.04  ? 321 PHE R O   1 
ATOM 3224 C CB  . PHE C 2 377 ? 130.628 136.635 120.949 1.00 91.04  ? 321 PHE R CB  1 
ATOM 3225 C CG  . PHE C 2 377 ? 130.248 135.188 121.011 1.00 91.04  ? 321 PHE R CG  1 
ATOM 3226 C CD1 . PHE C 2 377 ? 129.075 134.792 121.630 1.00 91.04  ? 321 PHE R CD1 1 
ATOM 3227 C CD2 . PHE C 2 377 ? 131.069 134.220 120.462 1.00 91.04  ? 321 PHE R CD2 1 
ATOM 3228 C CE1 . PHE C 2 377 ? 128.724 133.460 121.693 1.00 91.04  ? 321 PHE R CE1 1 
ATOM 3229 C CE2 . PHE C 2 377 ? 130.724 132.886 120.523 1.00 91.04  ? 321 PHE R CE2 1 
ATOM 3230 C CZ  . PHE C 2 377 ? 129.550 132.505 121.140 1.00 91.04  ? 321 PHE R CZ  1 
ATOM 3231 N N   . ARG C 2 378 ? 131.266 139.606 121.776 1.00 91.26  ? 322 ARG R N   1 
ATOM 3232 C CA  . ARG C 2 378 ? 132.081 140.807 121.633 1.00 91.26  ? 322 ARG R CA  1 
ATOM 3233 C C   . ARG C 2 378 ? 132.734 141.179 122.957 1.00 91.26  ? 322 ARG R C   1 
ATOM 3234 O O   . ARG C 2 378 ? 133.948 141.400 123.024 1.00 91.26  ? 322 ARG R O   1 
ATOM 3235 C CB  . ARG C 2 378 ? 131.227 141.961 121.108 1.00 91.26  ? 322 ARG R CB  1 
ATOM 3236 C CG  . ARG C 2 378 ? 131.866 142.722 119.960 1.00 91.26  ? 322 ARG R CG  1 
ATOM 3237 C CD  . ARG C 2 378 ? 130.960 143.829 119.453 1.00 91.26  ? 322 ARG R CD  1 
ATOM 3238 N NE  . ARG C 2 378 ? 129.813 143.299 118.722 1.00 91.26  ? 322 ARG R NE  1 
ATOM 3239 C CZ  . ARG C 2 378 ? 128.545 143.422 119.095 1.00 91.26  ? 322 ARG R CZ  1 
ATOM 3240 N NH1 . ARG C 2 378 ? 128.203 144.060 120.203 1.00 91.26  ? 322 ARG R NH1 1 
ATOM 3241 N NH2 . ARG C 2 378 ? 127.593 142.887 118.336 1.00 91.26  ? 322 ARG R NH2 1 
ATOM 3242 N N   . HIS C 2 379 ? 131.941 141.243 124.029 1.00 99.92  ? 323 HIS R N   1 
ATOM 3243 C CA  . HIS C 2 379 ? 132.506 141.523 125.344 1.00 99.92  ? 323 HIS R CA  1 
ATOM 3244 C C   . HIS C 2 379 ? 133.442 140.407 125.788 1.00 99.92  ? 323 HIS R C   1 
ATOM 3245 O O   . HIS C 2 379 ? 134.454 140.661 126.451 1.00 99.92  ? 323 HIS R O   1 
ATOM 3246 C CB  . HIS C 2 379 ? 131.386 141.718 126.365 1.00 99.92  ? 323 HIS R CB  1 
ATOM 3247 C CG  . HIS C 2 379 ? 131.843 141.618 127.787 1.00 99.92  ? 323 HIS R CG  1 
ATOM 3248 N ND1 . HIS C 2 379 ? 132.859 142.396 128.299 1.00 99.92  ? 323 HIS R ND1 1 
ATOM 3249 C CD2 . HIS C 2 379 ? 131.423 140.831 128.805 1.00 99.92  ? 323 HIS R CD2 1 
ATOM 3250 C CE1 . HIS C 2 379 ? 133.045 142.092 129.571 1.00 99.92  ? 323 HIS R CE1 1 
ATOM 3251 N NE2 . HIS C 2 379 ? 132.186 141.145 129.903 1.00 99.92  ? 323 HIS R NE2 1 
ATOM 3252 N N   . GLY C 2 380 ? 133.119 139.163 125.434 1.00 91.82  ? 324 GLY R N   1 
ATOM 3253 C CA  . GLY C 2 380 ? 133.969 138.053 125.833 1.00 91.82  ? 324 GLY R CA  1 
ATOM 3254 C C   . GLY C 2 380 ? 135.361 138.147 125.239 1.00 91.82  ? 324 GLY R C   1 
ATOM 3255 O O   . GLY C 2 380 ? 136.361 137.945 125.934 1.00 91.82  ? 324 GLY R O   1 
ATOM 3256 N N   . LEU C 2 381 ? 135.447 138.469 123.948 1.00 84.87  ? 325 LEU R N   1 
ATOM 3257 C CA  . LEU C 2 381 ? 136.744 138.508 123.279 1.00 84.87  ? 325 LEU R CA  1 
ATOM 3258 C C   . LEU C 2 381 ? 137.661 139.540 123.925 1.00 84.87  ? 325 LEU R C   1 
ATOM 3259 O O   . LEU C 2 381 ? 138.855 139.291 124.124 1.00 84.87  ? 325 LEU R O   1 
ATOM 3260 C CB  . LEU C 2 381 ? 136.552 138.809 121.792 1.00 84.87  ? 325 LEU R CB  1 
ATOM 3261 C CG  . LEU C 2 381 ? 137.806 139.175 120.995 1.00 84.87  ? 325 LEU R CG  1 
ATOM 3262 C CD1 . LEU C 2 381 ? 138.877 138.107 121.142 1.00 84.87  ? 325 LEU R CD1 1 
ATOM 3263 C CD2 . LEU C 2 381 ? 137.456 139.382 119.531 1.00 84.87  ? 325 LEU R CD2 1 
ATOM 3264 N N   . LEU C 2 382 ? 137.116 140.710 124.262 1.00 84.42  ? 326 LEU R N   1 
ATOM 3265 C CA  . LEU C 2 382 ? 137.932 141.753 124.875 1.00 84.42  ? 326 LEU R CA  1 
ATOM 3266 C C   . LEU C 2 382 ? 138.504 141.288 126.208 1.00 84.42  ? 326 LEU R C   1 
ATOM 3267 O O   . LEU C 2 382 ? 139.686 141.504 126.500 1.00 84.42  ? 326 LEU R O   1 
ATOM 3268 C CB  . LEU C 2 382 ? 137.101 143.024 125.061 1.00 84.42  ? 326 LEU R CB  1 
ATOM 3269 C CG  . LEU C 2 382 ? 136.385 143.557 123.817 1.00 84.42  ? 326 LEU R CG  1 
ATOM 3270 C CD1 . LEU C 2 382 ? 135.864 144.965 124.065 1.00 84.42  ? 326 LEU R CD1 1 
ATOM 3271 C CD2 . LEU C 2 382 ? 137.299 143.530 122.602 1.00 84.42  ? 326 LEU R CD2 1 
ATOM 3272 N N   . LYS C 2 383 ? 137.677 140.642 127.033 1.00 83.17  ? 327 LYS R N   1 
ATOM 3273 C CA  . LYS C 2 383 ? 138.143 140.204 128.345 1.00 83.17  ? 327 LYS R CA  1 
ATOM 3274 C C   . LYS C 2 383 ? 139.231 139.145 128.223 1.00 83.17  ? 327 LYS R C   1 
ATOM 3275 O O   . LYS C 2 383 ? 140.187 139.137 129.007 1.00 83.17  ? 327 LYS R O   1 
ATOM 3276 C CB  . LYS C 2 383 ? 136.970 139.674 129.169 1.00 83.17  ? 327 LYS R CB  1 
ATOM 3277 C CG  . LYS C 2 383 ? 137.388 138.972 130.452 1.00 83.17  ? 327 LYS R CG  1 
ATOM 3278 C CD  . LYS C 2 383 ? 136.316 139.080 131.526 1.00 83.17  ? 327 LYS R CD  1 
ATOM 3279 C CE  . LYS C 2 383 ? 136.581 140.249 132.462 1.00 83.17  ? 327 LYS R CE  1 
ATOM 3280 N NZ  . LYS C 2 383 ? 137.630 139.935 133.471 1.00 83.17  ? 327 LYS R NZ  1 
ATOM 3281 N N   . ILE C 2 384 ? 139.105 138.241 127.249 1.00 88.69  ? 328 ILE R N   1 
ATOM 3282 C CA  . ILE C 2 384 ? 140.092 137.177 127.097 1.00 88.69  ? 328 ILE R CA  1 
ATOM 3283 C C   . ILE C 2 384 ? 141.453 137.756 126.737 1.00 88.69  ? 328 ILE R C   1 
ATOM 3284 O O   . ILE C 2 384 ? 142.493 137.240 127.162 1.00 88.69  ? 328 ILE R O   1 
ATOM 3285 C CB  . ILE C 2 384 ? 139.622 136.154 126.046 1.00 88.69  ? 328 ILE R CB  1 
ATOM 3286 C CG1 . ILE C 2 384 ? 138.339 135.453 126.505 1.00 88.69  ? 328 ILE R CG1 1 
ATOM 3287 C CG2 . ILE C 2 384 ? 140.719 135.136 125.769 1.00 88.69  ? 328 ILE R CG2 1 
ATOM 3288 C CD1 . ILE C 2 384 ? 138.446 134.776 127.854 1.00 88.69  ? 328 ILE R CD1 1 
ATOM 3289 N N   . LEU C 2 385 ? 141.473 138.830 125.945 1.00 81.94  ? 329 LEU R N   1 
ATOM 3290 C CA  . LEU C 2 385 ? 142.742 139.418 125.532 1.00 81.94  ? 329 LEU R CA  1 
ATOM 3291 C C   . LEU C 2 385 ? 143.571 139.834 126.743 1.00 81.94  ? 329 LEU R C   1 
ATOM 3292 O O   . LEU C 2 385 ? 144.680 139.329 126.954 1.00 81.94  ? 329 LEU R O   1 
ATOM 3293 C CB  . LEU C 2 385 ? 142.487 140.613 124.614 1.00 81.94  ? 329 LEU R CB  1 
ATOM 3294 C CG  . LEU C 2 385 ? 142.009 140.261 123.203 1.00 81.94  ? 329 LEU R CG  1 
ATOM 3295 C CD1 . LEU C 2 385 ? 141.352 141.462 122.543 1.00 81.94  ? 329 LEU R CD1 1 
ATOM 3296 C CD2 . LEU C 2 385 ? 143.160 139.746 122.353 1.00 81.94  ? 329 LEU R CD2 1 
ATOM 3297 N N   . ALA C 2 386 ? 143.045 140.747 127.552 1.00 81.94  ? 330 ALA R N   1 
ATOM 3298 C CA  . ALA C 2 386 ? 143.744 141.199 128.750 1.00 81.94  ? 330 ALA R CA  1 
ATOM 3299 C C   . ALA C 2 386 ? 145.083 141.839 128.398 1.00 81.94  ? 330 ALA R C   1 
ATOM 3300 O O   . ALA C 2 386 ? 146.111 141.163 128.349 1.00 81.94  ? 330 ALA R O   1 
ATOM 3301 C CB  . ALA C 2 386 ? 143.947 140.040 129.714 1.00 81.94  ? 330 ALA R CB  1 
# 
