data_8XVU
# 
_entry.id   8XVU 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XVU         pdb_00008xvu 10.2210/pdb8xvu/pdb 
WWPDB D_1300044259 ?            ?                   
EMDB  EMD-38719    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-15 ? 
2 'Structure model' 1 1 2025-04-09 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_ASTM'         
4  2 'Structure model' '_citation.journal_id_CSD'          
5  2 'Structure model' '_citation.journal_id_ISSN'         
6  2 'Structure model' '_citation.journal_volume'          
7  2 'Structure model' '_citation.page_first'              
8  2 'Structure model' '_citation.page_last'               
9  2 'Structure model' '_citation.pdbx_database_id_DOI'    
10 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
11 2 'Structure model' '_citation.title'                   
12 2 'Structure model' '_citation.year'                    
13 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XVU 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-15 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Structure of CXCR2 bound to CXCL2 (Ligand-receptor focused map)' 
_pdbx_database_related.db_id          EMD-38719 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 arshukla@iitk.ac.in       Arun  Shukla K 'principal investigator/group leader' 0000-0003-2910-8288 
3 nureki@bs.s.u-tokyo.ac.jp Osamu Nureki ? 'principal investigator/group leader' 0000-0003-1813-7008 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Sano, F.K.'   1 0000-0002-8965-788X 
'Saha, S.'     2 0000-0002-0036-4969 
'Sharma, S.'   3 0009-0005-9109-9054 
'Ganguly, M.'  4 0009-0007-6165-3063 
'Shihoya, W.'  5 0000-0003-4813-5740 
'Nureki, O.'   6 0000-0003-1813-7008 
'Shukla, A.K.' 7 0000-0003-2910-8288 
'Banerjee, R.' 8 0000-0002-7751-2317 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mol.Cell 
_citation.journal_id_ASTM           MOCEFL 
_citation.journal_id_CSD            2168 
_citation.journal_id_ISSN           1097-2765 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            85 
_citation.language                  ? 
_citation.page_first                976 
_citation.page_last                 988.e9 
_citation.title                     
'Molecular basis of promiscuous chemokine binding and structural mimicry at the C-X-C chemokine receptor, CXCR2.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.molcel.2025.01.024 
_citation.pdbx_database_id_PubMed   39978339 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Saha, S.'        1  ? 
primary 'Sano, F.K.'      2  ? 
primary 'Sharma, S.'      3  ? 
primary 'Ganguly, M.'     4  ? 
primary 'Mishra, S.'      5  ? 
primary 'Dalal, A.'       6  ? 
primary 'Akasaka, H.'     7  ? 
primary 'Kobayashi, T.A.' 8  ? 
primary 'Zaidi, N.'       9  ? 
primary 'Tiwari, D.'      10 ? 
primary 'Roy, N.'         11 ? 
primary 'Yadav, M.K.'     12 ? 
primary 'Banerjee, N.'    13 ? 
primary 'Saha, S.'        14 ? 
primary 'Mohapatra, S.'   15 ? 
primary 'Itoh, Y.'        16 ? 
primary 'Chevigne, A.'    17 ? 
primary 'Banerjee, R.'    18 ? 
primary 'Shihoya, W.'     19 ? 
primary 'Nureki, O.'      20 ? 
primary 'Shukla, A.K.'    21 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'C-X-C chemokine receptor type 2' 46699.609 1 ? ? ? ? 
2 polymer man 'C-X-C motif chemokine 2'         7905.440  2 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        CXC-R2,CXCR-2 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
;MGKTIIALSYIFCLVFADYKDDDDAANFTPVNGSSGNQSVRLVTSSSLEVLFQGPGSEDFNMESDSFEDFWKGEDLSNYS
YSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIW
AASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFR
RTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCW
LPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDS
RPSFVGSSSGHTSTTL
;
R   ? 
2 'polypeptide(L)' no no APLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN 
APLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN D,E ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   LYS n 
1 4   THR n 
1 5   ILE n 
1 6   ILE n 
1 7   ALA n 
1 8   LEU n 
1 9   SER n 
1 10  TYR n 
1 11  ILE n 
1 12  PHE n 
1 13  CYS n 
1 14  LEU n 
1 15  VAL n 
1 16  PHE n 
1 17  ALA n 
1 18  ASP n 
1 19  TYR n 
1 20  LYS n 
1 21  ASP n 
1 22  ASP n 
1 23  ASP n 
1 24  ASP n 
1 25  ALA n 
1 26  ALA n 
1 27  ASN n 
1 28  PHE n 
1 29  THR n 
1 30  PRO n 
1 31  VAL n 
1 32  ASN n 
1 33  GLY n 
1 34  SER n 
1 35  SER n 
1 36  GLY n 
1 37  ASN n 
1 38  GLN n 
1 39  SER n 
1 40  VAL n 
1 41  ARG n 
1 42  LEU n 
1 43  VAL n 
1 44  THR n 
1 45  SER n 
1 46  SER n 
1 47  SER n 
1 48  LEU n 
1 49  GLU n 
1 50  VAL n 
1 51  LEU n 
1 52  PHE n 
1 53  GLN n 
1 54  GLY n 
1 55  PRO n 
1 56  GLY n 
1 57  SER n 
1 58  GLU n 
1 59  ASP n 
1 60  PHE n 
1 61  ASN n 
1 62  MET n 
1 63  GLU n 
1 64  SER n 
1 65  ASP n 
1 66  SER n 
1 67  PHE n 
1 68  GLU n 
1 69  ASP n 
1 70  PHE n 
1 71  TRP n 
1 72  LYS n 
1 73  GLY n 
1 74  GLU n 
1 75  ASP n 
1 76  LEU n 
1 77  SER n 
1 78  ASN n 
1 79  TYR n 
1 80  SER n 
1 81  TYR n 
1 82  SER n 
1 83  SER n 
1 84  THR n 
1 85  LEU n 
1 86  PRO n 
1 87  PRO n 
1 88  PHE n 
1 89  LEU n 
1 90  LEU n 
1 91  ASP n 
1 92  ALA n 
1 93  ALA n 
1 94  PRO n 
1 95  CYS n 
1 96  GLU n 
1 97  PRO n 
1 98  GLU n 
1 99  SER n 
1 100 LEU n 
1 101 GLU n 
1 102 ILE n 
1 103 ASN n 
1 104 LYS n 
1 105 TYR n 
1 106 PHE n 
1 107 VAL n 
1 108 VAL n 
1 109 ILE n 
1 110 ILE n 
1 111 TYR n 
1 112 ALA n 
1 113 LEU n 
1 114 VAL n 
1 115 PHE n 
1 116 LEU n 
1 117 LEU n 
1 118 SER n 
1 119 LEU n 
1 120 LEU n 
1 121 GLY n 
1 122 ASN n 
1 123 SER n 
1 124 LEU n 
1 125 VAL n 
1 126 MET n 
1 127 LEU n 
1 128 VAL n 
1 129 ILE n 
1 130 LEU n 
1 131 TYR n 
1 132 SER n 
1 133 ARG n 
1 134 VAL n 
1 135 GLY n 
1 136 ARG n 
1 137 SER n 
1 138 VAL n 
1 139 THR n 
1 140 ASP n 
1 141 VAL n 
1 142 TYR n 
1 143 LEU n 
1 144 LEU n 
1 145 ASN n 
1 146 LEU n 
1 147 ALA n 
1 148 LEU n 
1 149 ALA n 
1 150 ASP n 
1 151 LEU n 
1 152 LEU n 
1 153 PHE n 
1 154 ALA n 
1 155 LEU n 
1 156 THR n 
1 157 LEU n 
1 158 PRO n 
1 159 ILE n 
1 160 TRP n 
1 161 ALA n 
1 162 ALA n 
1 163 SER n 
1 164 LYS n 
1 165 VAL n 
1 166 ASN n 
1 167 GLY n 
1 168 TRP n 
1 169 ILE n 
1 170 PHE n 
1 171 GLY n 
1 172 THR n 
1 173 PHE n 
1 174 LEU n 
1 175 CYS n 
1 176 LYS n 
1 177 VAL n 
1 178 VAL n 
1 179 SER n 
1 180 LEU n 
1 181 LEU n 
1 182 LYS n 
1 183 GLU n 
1 184 VAL n 
1 185 ASN n 
1 186 PHE n 
1 187 TYR n 
1 188 SER n 
1 189 GLY n 
1 190 ILE n 
1 191 LEU n 
1 192 LEU n 
1 193 LEU n 
1 194 ALA n 
1 195 CYS n 
1 196 ILE n 
1 197 SER n 
1 198 VAL n 
1 199 ASP n 
1 200 ARG n 
1 201 TYR n 
1 202 LEU n 
1 203 ALA n 
1 204 ILE n 
1 205 VAL n 
1 206 HIS n 
1 207 ALA n 
1 208 THR n 
1 209 ARG n 
1 210 THR n 
1 211 LEU n 
1 212 THR n 
1 213 GLN n 
1 214 LYS n 
1 215 ARG n 
1 216 TYR n 
1 217 LEU n 
1 218 VAL n 
1 219 LYS n 
1 220 PHE n 
1 221 ILE n 
1 222 CYS n 
1 223 LEU n 
1 224 SER n 
1 225 ILE n 
1 226 TRP n 
1 227 GLY n 
1 228 LEU n 
1 229 SER n 
1 230 LEU n 
1 231 LEU n 
1 232 LEU n 
1 233 ALA n 
1 234 LEU n 
1 235 PRO n 
1 236 VAL n 
1 237 LEU n 
1 238 LEU n 
1 239 PHE n 
1 240 ARG n 
1 241 ARG n 
1 242 THR n 
1 243 VAL n 
1 244 TYR n 
1 245 SER n 
1 246 SER n 
1 247 ASN n 
1 248 VAL n 
1 249 SER n 
1 250 PRO n 
1 251 ALA n 
1 252 CYS n 
1 253 TYR n 
1 254 GLU n 
1 255 ASP n 
1 256 MET n 
1 257 GLY n 
1 258 ASN n 
1 259 ASN n 
1 260 THR n 
1 261 ALA n 
1 262 ASN n 
1 263 TRP n 
1 264 ARG n 
1 265 MET n 
1 266 LEU n 
1 267 LEU n 
1 268 ARG n 
1 269 ILE n 
1 270 LEU n 
1 271 PRO n 
1 272 GLN n 
1 273 SER n 
1 274 PHE n 
1 275 GLY n 
1 276 PHE n 
1 277 ILE n 
1 278 VAL n 
1 279 PRO n 
1 280 LEU n 
1 281 LEU n 
1 282 ILE n 
1 283 MET n 
1 284 LEU n 
1 285 PHE n 
1 286 CYS n 
1 287 TYR n 
1 288 GLY n 
1 289 PHE n 
1 290 THR n 
1 291 LEU n 
1 292 ARG n 
1 293 THR n 
1 294 LEU n 
1 295 PHE n 
1 296 LYS n 
1 297 ALA n 
1 298 HIS n 
1 299 MET n 
1 300 GLY n 
1 301 GLN n 
1 302 LYS n 
1 303 HIS n 
1 304 ARG n 
1 305 ALA n 
1 306 MET n 
1 307 ARG n 
1 308 VAL n 
1 309 ILE n 
1 310 PHE n 
1 311 ALA n 
1 312 VAL n 
1 313 VAL n 
1 314 LEU n 
1 315 ILE n 
1 316 PHE n 
1 317 LEU n 
1 318 LEU n 
1 319 CYS n 
1 320 TRP n 
1 321 LEU n 
1 322 PRO n 
1 323 TYR n 
1 324 ASN n 
1 325 LEU n 
1 326 VAL n 
1 327 LEU n 
1 328 LEU n 
1 329 ALA n 
1 330 ASP n 
1 331 THR n 
1 332 LEU n 
1 333 MET n 
1 334 ARG n 
1 335 THR n 
1 336 GLN n 
1 337 VAL n 
1 338 ILE n 
1 339 GLN n 
1 340 GLU n 
1 341 THR n 
1 342 CYS n 
1 343 GLU n 
1 344 ARG n 
1 345 ARG n 
1 346 ASN n 
1 347 HIS n 
1 348 ILE n 
1 349 ASP n 
1 350 ARG n 
1 351 ALA n 
1 352 LEU n 
1 353 ASP n 
1 354 ALA n 
1 355 THR n 
1 356 GLU n 
1 357 ILE n 
1 358 LEU n 
1 359 GLY n 
1 360 ILE n 
1 361 LEU n 
1 362 HIS n 
1 363 SER n 
1 364 CYS n 
1 365 LEU n 
1 366 ASN n 
1 367 PRO n 
1 368 LEU n 
1 369 ILE n 
1 370 TYR n 
1 371 ALA n 
1 372 PHE n 
1 373 ILE n 
1 374 GLY n 
1 375 GLN n 
1 376 LYS n 
1 377 PHE n 
1 378 ARG n 
1 379 HIS n 
1 380 GLY n 
1 381 LEU n 
1 382 LEU n 
1 383 LYS n 
1 384 ILE n 
1 385 LEU n 
1 386 ALA n 
1 387 ILE n 
1 388 HIS n 
1 389 GLY n 
1 390 LEU n 
1 391 ILE n 
1 392 SER n 
1 393 LYS n 
1 394 ASP n 
1 395 SER n 
1 396 LEU n 
1 397 PRO n 
1 398 LYS n 
1 399 ASP n 
1 400 SER n 
1 401 ARG n 
1 402 PRO n 
1 403 SER n 
1 404 PHE n 
1 405 VAL n 
1 406 GLY n 
1 407 SER n 
1 408 SER n 
1 409 SER n 
1 410 GLY n 
1 411 HIS n 
1 412 THR n 
1 413 SER n 
1 414 THR n 
1 415 THR n 
1 416 LEU n 
2 1   ALA n 
2 2   PRO n 
2 3   LEU n 
2 4   ALA n 
2 5   THR n 
2 6   GLU n 
2 7   LEU n 
2 8   ARG n 
2 9   CYS n 
2 10  GLN n 
2 11  CYS n 
2 12  LEU n 
2 13  GLN n 
2 14  THR n 
2 15  LEU n 
2 16  GLN n 
2 17  GLY n 
2 18  ILE n 
2 19  HIS n 
2 20  LEU n 
2 21  LYS n 
2 22  ASN n 
2 23  ILE n 
2 24  GLN n 
2 25  SER n 
2 26  VAL n 
2 27  LYS n 
2 28  VAL n 
2 29  LYS n 
2 30  SER n 
2 31  PRO n 
2 32  GLY n 
2 33  PRO n 
2 34  HIS n 
2 35  CYS n 
2 36  ALA n 
2 37  GLN n 
2 38  THR n 
2 39  GLU n 
2 40  VAL n 
2 41  ILE n 
2 42  ALA n 
2 43  THR n 
2 44  LEU n 
2 45  LYS n 
2 46  ASN n 
2 47  GLY n 
2 48  GLN n 
2 49  LYS n 
2 50  ALA n 
2 51  CYS n 
2 52  LEU n 
2 53  ASN n 
2 54  PRO n 
2 55  ALA n 
2 56  SER n 
2 57  PRO n 
2 58  MET n 
2 59  VAL n 
2 60  LYS n 
2 61  LYS n 
2 62  ILE n 
2 63  ILE n 
2 64  GLU n 
2 65  LYS n 
2 66  MET n 
2 67  LEU n 
2 68  LYS n 
2 69  ASN n 
2 70  GLY n 
2 71  LYS n 
2 72  SER n 
2 73  ASN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 416 human ? CXCR2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 73  human ? CXCL2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Escherichia coli'      562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   -55 ?   ?   ?   R . n 
A 1 2   GLY 2   -54 ?   ?   ?   R . n 
A 1 3   LYS 3   -53 ?   ?   ?   R . n 
A 1 4   THR 4   -52 ?   ?   ?   R . n 
A 1 5   ILE 5   -51 ?   ?   ?   R . n 
A 1 6   ILE 6   -50 ?   ?   ?   R . n 
A 1 7   ALA 7   -49 ?   ?   ?   R . n 
A 1 8   LEU 8   -48 ?   ?   ?   R . n 
A 1 9   SER 9   -47 ?   ?   ?   R . n 
A 1 10  TYR 10  -46 ?   ?   ?   R . n 
A 1 11  ILE 11  -45 ?   ?   ?   R . n 
A 1 12  PHE 12  -44 ?   ?   ?   R . n 
A 1 13  CYS 13  -43 ?   ?   ?   R . n 
A 1 14  LEU 14  -42 ?   ?   ?   R . n 
A 1 15  VAL 15  -41 ?   ?   ?   R . n 
A 1 16  PHE 16  -40 ?   ?   ?   R . n 
A 1 17  ALA 17  -39 ?   ?   ?   R . n 
A 1 18  ASP 18  -38 ?   ?   ?   R . n 
A 1 19  TYR 19  -37 ?   ?   ?   R . n 
A 1 20  LYS 20  -36 ?   ?   ?   R . n 
A 1 21  ASP 21  -35 ?   ?   ?   R . n 
A 1 22  ASP 22  -34 ?   ?   ?   R . n 
A 1 23  ASP 23  -33 ?   ?   ?   R . n 
A 1 24  ASP 24  -32 ?   ?   ?   R . n 
A 1 25  ALA 25  -31 ?   ?   ?   R . n 
A 1 26  ALA 26  -30 ?   ?   ?   R . n 
A 1 27  ASN 27  -29 ?   ?   ?   R . n 
A 1 28  PHE 28  -28 ?   ?   ?   R . n 
A 1 29  THR 29  -27 ?   ?   ?   R . n 
A 1 30  PRO 30  -26 ?   ?   ?   R . n 
A 1 31  VAL 31  -25 ?   ?   ?   R . n 
A 1 32  ASN 32  -24 ?   ?   ?   R . n 
A 1 33  GLY 33  -23 ?   ?   ?   R . n 
A 1 34  SER 34  -22 ?   ?   ?   R . n 
A 1 35  SER 35  -21 ?   ?   ?   R . n 
A 1 36  GLY 36  -20 ?   ?   ?   R . n 
A 1 37  ASN 37  -19 ?   ?   ?   R . n 
A 1 38  GLN 38  -18 ?   ?   ?   R . n 
A 1 39  SER 39  -17 ?   ?   ?   R . n 
A 1 40  VAL 40  -16 ?   ?   ?   R . n 
A 1 41  ARG 41  -15 ?   ?   ?   R . n 
A 1 42  LEU 42  -14 ?   ?   ?   R . n 
A 1 43  VAL 43  -13 ?   ?   ?   R . n 
A 1 44  THR 44  -12 ?   ?   ?   R . n 
A 1 45  SER 45  -11 ?   ?   ?   R . n 
A 1 46  SER 46  -10 ?   ?   ?   R . n 
A 1 47  SER 47  -9  ?   ?   ?   R . n 
A 1 48  LEU 48  -8  ?   ?   ?   R . n 
A 1 49  GLU 49  -7  ?   ?   ?   R . n 
A 1 50  VAL 50  -6  ?   ?   ?   R . n 
A 1 51  LEU 51  -5  ?   ?   ?   R . n 
A 1 52  PHE 52  -4  ?   ?   ?   R . n 
A 1 53  GLN 53  -3  ?   ?   ?   R . n 
A 1 54  GLY 54  -2  ?   ?   ?   R . n 
A 1 55  PRO 55  -1  ?   ?   ?   R . n 
A 1 56  GLY 56  0   ?   ?   ?   R . n 
A 1 57  SER 57  1   ?   ?   ?   R . n 
A 1 58  GLU 58  2   ?   ?   ?   R . n 
A 1 59  ASP 59  3   ?   ?   ?   R . n 
A 1 60  PHE 60  4   ?   ?   ?   R . n 
A 1 61  ASN 61  5   ?   ?   ?   R . n 
A 1 62  MET 62  6   ?   ?   ?   R . n 
A 1 63  GLU 63  7   ?   ?   ?   R . n 
A 1 64  SER 64  8   ?   ?   ?   R . n 
A 1 65  ASP 65  9   ?   ?   ?   R . n 
A 1 66  SER 66  10  ?   ?   ?   R . n 
A 1 67  PHE 67  11  ?   ?   ?   R . n 
A 1 68  GLU 68  12  ?   ?   ?   R . n 
A 1 69  ASP 69  13  ?   ?   ?   R . n 
A 1 70  PHE 70  14  ?   ?   ?   R . n 
A 1 71  TRP 71  15  ?   ?   ?   R . n 
A 1 72  LYS 72  16  ?   ?   ?   R . n 
A 1 73  GLY 73  17  ?   ?   ?   R . n 
A 1 74  GLU 74  18  ?   ?   ?   R . n 
A 1 75  ASP 75  19  ?   ?   ?   R . n 
A 1 76  LEU 76  20  ?   ?   ?   R . n 
A 1 77  SER 77  21  ?   ?   ?   R . n 
A 1 78  ASN 78  22  ?   ?   ?   R . n 
A 1 79  TYR 79  23  ?   ?   ?   R . n 
A 1 80  SER 80  24  ?   ?   ?   R . n 
A 1 81  TYR 81  25  ?   ?   ?   R . n 
A 1 82  SER 82  26  ?   ?   ?   R . n 
A 1 83  SER 83  27  ?   ?   ?   R . n 
A 1 84  THR 84  28  ?   ?   ?   R . n 
A 1 85  LEU 85  29  ?   ?   ?   R . n 
A 1 86  PRO 86  30  ?   ?   ?   R . n 
A 1 87  PRO 87  31  ?   ?   ?   R . n 
A 1 88  PHE 88  32  ?   ?   ?   R . n 
A 1 89  LEU 89  33  33  LEU LEU R . n 
A 1 90  LEU 90  34  34  LEU LEU R . n 
A 1 91  ASP 91  35  35  ASP ASP R . n 
A 1 92  ALA 92  36  36  ALA ALA R . n 
A 1 93  ALA 93  37  37  ALA ALA R . n 
A 1 94  PRO 94  38  38  PRO PRO R . n 
A 1 95  CYS 95  39  39  CYS CYS R . n 
A 1 96  GLU 96  40  40  GLU GLU R . n 
A 1 97  PRO 97  41  41  PRO PRO R . n 
A 1 98  GLU 98  42  42  GLU GLU R . n 
A 1 99  SER 99  43  43  SER SER R . n 
A 1 100 LEU 100 44  44  LEU LEU R . n 
A 1 101 GLU 101 45  45  GLU GLU R . n 
A 1 102 ILE 102 46  46  ILE ILE R . n 
A 1 103 ASN 103 47  47  ASN ASN R . n 
A 1 104 LYS 104 48  48  LYS LYS R . n 
A 1 105 TYR 105 49  49  TYR TYR R . n 
A 1 106 PHE 106 50  50  PHE PHE R . n 
A 1 107 VAL 107 51  51  VAL VAL R . n 
A 1 108 VAL 108 52  52  VAL VAL R . n 
A 1 109 ILE 109 53  53  ILE ILE R . n 
A 1 110 ILE 110 54  54  ILE ILE R . n 
A 1 111 TYR 111 55  55  TYR TYR R . n 
A 1 112 ALA 112 56  56  ALA ALA R . n 
A 1 113 LEU 113 57  57  LEU LEU R . n 
A 1 114 VAL 114 58  58  VAL VAL R . n 
A 1 115 PHE 115 59  59  PHE PHE R . n 
A 1 116 LEU 116 60  60  LEU LEU R . n 
A 1 117 LEU 117 61  61  LEU LEU R . n 
A 1 118 SER 118 62  62  SER SER R . n 
A 1 119 LEU 119 63  63  LEU LEU R . n 
A 1 120 LEU 120 64  64  LEU LEU R . n 
A 1 121 GLY 121 65  65  GLY GLY R . n 
A 1 122 ASN 122 66  66  ASN ASN R . n 
A 1 123 SER 123 67  67  SER SER R . n 
A 1 124 LEU 124 68  68  LEU LEU R . n 
A 1 125 VAL 125 69  69  VAL VAL R . n 
A 1 126 MET 126 70  70  MET MET R . n 
A 1 127 LEU 127 71  71  LEU LEU R . n 
A 1 128 VAL 128 72  72  VAL VAL R . n 
A 1 129 ILE 129 73  73  ILE ILE R . n 
A 1 130 LEU 130 74  74  LEU LEU R . n 
A 1 131 TYR 131 75  75  TYR TYR R . n 
A 1 132 SER 132 76  76  SER SER R . n 
A 1 133 ARG 133 77  77  ARG ARG R . n 
A 1 134 VAL 134 78  78  VAL VAL R . n 
A 1 135 GLY 135 79  79  GLY GLY R . n 
A 1 136 ARG 136 80  80  ARG ARG R . n 
A 1 137 SER 137 81  81  SER SER R . n 
A 1 138 VAL 138 82  82  VAL VAL R . n 
A 1 139 THR 139 83  83  THR THR R . n 
A 1 140 ASP 140 84  84  ASP ASP R . n 
A 1 141 VAL 141 85  85  VAL VAL R . n 
A 1 142 TYR 142 86  86  TYR TYR R . n 
A 1 143 LEU 143 87  87  LEU LEU R . n 
A 1 144 LEU 144 88  88  LEU LEU R . n 
A 1 145 ASN 145 89  89  ASN ASN R . n 
A 1 146 LEU 146 90  90  LEU LEU R . n 
A 1 147 ALA 147 91  91  ALA ALA R . n 
A 1 148 LEU 148 92  92  LEU LEU R . n 
A 1 149 ALA 149 93  93  ALA ALA R . n 
A 1 150 ASP 150 94  94  ASP ASP R . n 
A 1 151 LEU 151 95  95  LEU LEU R . n 
A 1 152 LEU 152 96  96  LEU LEU R . n 
A 1 153 PHE 153 97  97  PHE PHE R . n 
A 1 154 ALA 154 98  98  ALA ALA R . n 
A 1 155 LEU 155 99  99  LEU LEU R . n 
A 1 156 THR 156 100 100 THR THR R . n 
A 1 157 LEU 157 101 101 LEU LEU R . n 
A 1 158 PRO 158 102 102 PRO PRO R . n 
A 1 159 ILE 159 103 103 ILE ILE R . n 
A 1 160 TRP 160 104 104 TRP TRP R . n 
A 1 161 ALA 161 105 105 ALA ALA R . n 
A 1 162 ALA 162 106 106 ALA ALA R . n 
A 1 163 SER 163 107 107 SER SER R . n 
A 1 164 LYS 164 108 108 LYS LYS R . n 
A 1 165 VAL 165 109 109 VAL VAL R . n 
A 1 166 ASN 166 110 110 ASN ASN R . n 
A 1 167 GLY 167 111 111 GLY GLY R . n 
A 1 168 TRP 168 112 112 TRP TRP R . n 
A 1 169 ILE 169 113 113 ILE ILE R . n 
A 1 170 PHE 170 114 114 PHE PHE R . n 
A 1 171 GLY 171 115 115 GLY GLY R . n 
A 1 172 THR 172 116 116 THR THR R . n 
A 1 173 PHE 173 117 117 PHE PHE R . n 
A 1 174 LEU 174 118 118 LEU LEU R . n 
A 1 175 CYS 175 119 119 CYS CYS R . n 
A 1 176 LYS 176 120 120 LYS LYS R . n 
A 1 177 VAL 177 121 121 VAL VAL R . n 
A 1 178 VAL 178 122 122 VAL VAL R . n 
A 1 179 SER 179 123 123 SER SER R . n 
A 1 180 LEU 180 124 124 LEU LEU R . n 
A 1 181 LEU 181 125 125 LEU LEU R . n 
A 1 182 LYS 182 126 126 LYS LYS R . n 
A 1 183 GLU 183 127 127 GLU GLU R . n 
A 1 184 VAL 184 128 128 VAL VAL R . n 
A 1 185 ASN 185 129 129 ASN ASN R . n 
A 1 186 PHE 186 130 130 PHE PHE R . n 
A 1 187 TYR 187 131 131 TYR TYR R . n 
A 1 188 SER 188 132 132 SER SER R . n 
A 1 189 GLY 189 133 133 GLY GLY R . n 
A 1 190 ILE 190 134 134 ILE ILE R . n 
A 1 191 LEU 191 135 135 LEU LEU R . n 
A 1 192 LEU 192 136 136 LEU LEU R . n 
A 1 193 LEU 193 137 137 LEU LEU R . n 
A 1 194 ALA 194 138 138 ALA ALA R . n 
A 1 195 CYS 195 139 139 CYS CYS R . n 
A 1 196 ILE 196 140 140 ILE ILE R . n 
A 1 197 SER 197 141 141 SER SER R . n 
A 1 198 VAL 198 142 142 VAL VAL R . n 
A 1 199 ASP 199 143 143 ASP ASP R . n 
A 1 200 ARG 200 144 144 ARG ARG R . n 
A 1 201 TYR 201 145 145 TYR TYR R . n 
A 1 202 LEU 202 146 146 LEU LEU R . n 
A 1 203 ALA 203 147 147 ALA ALA R . n 
A 1 204 ILE 204 148 148 ILE ILE R . n 
A 1 205 VAL 205 149 149 VAL VAL R . n 
A 1 206 HIS 206 150 150 HIS HIS R . n 
A 1 207 ALA 207 151 151 ALA ALA R . n 
A 1 208 THR 208 152 152 THR THR R . n 
A 1 209 ARG 209 153 153 ARG ARG R . n 
A 1 210 THR 210 154 154 THR THR R . n 
A 1 211 LEU 211 155 155 LEU LEU R . n 
A 1 212 THR 212 156 156 THR THR R . n 
A 1 213 GLN 213 157 157 GLN GLN R . n 
A 1 214 LYS 214 158 158 LYS LYS R . n 
A 1 215 ARG 215 159 159 ARG ARG R . n 
A 1 216 TYR 216 160 160 TYR TYR R . n 
A 1 217 LEU 217 161 161 LEU LEU R . n 
A 1 218 VAL 218 162 162 VAL VAL R . n 
A 1 219 LYS 219 163 163 LYS LYS R . n 
A 1 220 PHE 220 164 164 PHE PHE R . n 
A 1 221 ILE 221 165 165 ILE ILE R . n 
A 1 222 CYS 222 166 166 CYS CYS R . n 
A 1 223 LEU 223 167 167 LEU LEU R . n 
A 1 224 SER 224 168 168 SER SER R . n 
A 1 225 ILE 225 169 169 ILE ILE R . n 
A 1 226 TRP 226 170 170 TRP TRP R . n 
A 1 227 GLY 227 171 171 GLY GLY R . n 
A 1 228 LEU 228 172 172 LEU LEU R . n 
A 1 229 SER 229 173 173 SER SER R . n 
A 1 230 LEU 230 174 174 LEU LEU R . n 
A 1 231 LEU 231 175 175 LEU LEU R . n 
A 1 232 LEU 232 176 176 LEU LEU R . n 
A 1 233 ALA 233 177 177 ALA ALA R . n 
A 1 234 LEU 234 178 178 LEU LEU R . n 
A 1 235 PRO 235 179 179 PRO PRO R . n 
A 1 236 VAL 236 180 180 VAL VAL R . n 
A 1 237 LEU 237 181 181 LEU LEU R . n 
A 1 238 LEU 238 182 182 LEU LEU R . n 
A 1 239 PHE 239 183 183 PHE PHE R . n 
A 1 240 ARG 240 184 184 ARG ARG R . n 
A 1 241 ARG 241 185 185 ARG ARG R . n 
A 1 242 THR 242 186 186 THR THR R . n 
A 1 243 VAL 243 187 187 VAL VAL R . n 
A 1 244 TYR 244 188 188 TYR TYR R . n 
A 1 245 SER 245 189 189 SER SER R . n 
A 1 246 SER 246 190 190 SER SER R . n 
A 1 247 ASN 247 191 191 ASN ASN R . n 
A 1 248 VAL 248 192 192 VAL VAL R . n 
A 1 249 SER 249 193 193 SER SER R . n 
A 1 250 PRO 250 194 194 PRO PRO R . n 
A 1 251 ALA 251 195 195 ALA ALA R . n 
A 1 252 CYS 252 196 196 CYS CYS R . n 
A 1 253 TYR 253 197 197 TYR TYR R . n 
A 1 254 GLU 254 198 198 GLU GLU R . n 
A 1 255 ASP 255 199 199 ASP ASP R . n 
A 1 256 MET 256 200 200 MET MET R . n 
A 1 257 GLY 257 201 201 GLY GLY R . n 
A 1 258 ASN 258 202 202 ASN ASN R . n 
A 1 259 ASN 259 203 203 ASN ASN R . n 
A 1 260 THR 260 204 204 THR THR R . n 
A 1 261 ALA 261 205 205 ALA ALA R . n 
A 1 262 ASN 262 206 206 ASN ASN R . n 
A 1 263 TRP 263 207 207 TRP TRP R . n 
A 1 264 ARG 264 208 208 ARG ARG R . n 
A 1 265 MET 265 209 209 MET MET R . n 
A 1 266 LEU 266 210 210 LEU LEU R . n 
A 1 267 LEU 267 211 211 LEU LEU R . n 
A 1 268 ARG 268 212 212 ARG ARG R . n 
A 1 269 ILE 269 213 213 ILE ILE R . n 
A 1 270 LEU 270 214 214 LEU LEU R . n 
A 1 271 PRO 271 215 215 PRO PRO R . n 
A 1 272 GLN 272 216 216 GLN GLN R . n 
A 1 273 SER 273 217 217 SER SER R . n 
A 1 274 PHE 274 218 218 PHE PHE R . n 
A 1 275 GLY 275 219 219 GLY GLY R . n 
A 1 276 PHE 276 220 220 PHE PHE R . n 
A 1 277 ILE 277 221 221 ILE ILE R . n 
A 1 278 VAL 278 222 222 VAL VAL R . n 
A 1 279 PRO 279 223 223 PRO PRO R . n 
A 1 280 LEU 280 224 224 LEU LEU R . n 
A 1 281 LEU 281 225 225 LEU LEU R . n 
A 1 282 ILE 282 226 226 ILE ILE R . n 
A 1 283 MET 283 227 227 MET MET R . n 
A 1 284 LEU 284 228 228 LEU LEU R . n 
A 1 285 PHE 285 229 229 PHE PHE R . n 
A 1 286 CYS 286 230 230 CYS CYS R . n 
A 1 287 TYR 287 231 231 TYR TYR R . n 
A 1 288 GLY 288 232 232 GLY GLY R . n 
A 1 289 PHE 289 233 233 PHE PHE R . n 
A 1 290 THR 290 234 234 THR THR R . n 
A 1 291 LEU 291 235 235 LEU LEU R . n 
A 1 292 ARG 292 236 236 ARG ARG R . n 
A 1 293 THR 293 237 237 THR THR R . n 
A 1 294 LEU 294 238 238 LEU LEU R . n 
A 1 295 PHE 295 239 239 PHE PHE R . n 
A 1 296 LYS 296 240 240 LYS LYS R . n 
A 1 297 ALA 297 241 241 ALA ALA R . n 
A 1 298 HIS 298 242 242 HIS HIS R . n 
A 1 299 MET 299 243 243 MET MET R . n 
A 1 300 GLY 300 244 244 GLY GLY R . n 
A 1 301 GLN 301 245 245 GLN GLN R . n 
A 1 302 LYS 302 246 246 LYS LYS R . n 
A 1 303 HIS 303 247 247 HIS HIS R . n 
A 1 304 ARG 304 248 248 ARG ARG R . n 
A 1 305 ALA 305 249 249 ALA ALA R . n 
A 1 306 MET 306 250 250 MET MET R . n 
A 1 307 ARG 307 251 251 ARG ARG R . n 
A 1 308 VAL 308 252 252 VAL VAL R . n 
A 1 309 ILE 309 253 253 ILE ILE R . n 
A 1 310 PHE 310 254 254 PHE PHE R . n 
A 1 311 ALA 311 255 255 ALA ALA R . n 
A 1 312 VAL 312 256 256 VAL VAL R . n 
A 1 313 VAL 313 257 257 VAL VAL R . n 
A 1 314 LEU 314 258 258 LEU LEU R . n 
A 1 315 ILE 315 259 259 ILE ILE R . n 
A 1 316 PHE 316 260 260 PHE PHE R . n 
A 1 317 LEU 317 261 261 LEU LEU R . n 
A 1 318 LEU 318 262 262 LEU LEU R . n 
A 1 319 CYS 319 263 263 CYS CYS R . n 
A 1 320 TRP 320 264 264 TRP TRP R . n 
A 1 321 LEU 321 265 265 LEU LEU R . n 
A 1 322 PRO 322 266 266 PRO PRO R . n 
A 1 323 TYR 323 267 267 TYR TYR R . n 
A 1 324 ASN 324 268 268 ASN ASN R . n 
A 1 325 LEU 325 269 269 LEU LEU R . n 
A 1 326 VAL 326 270 270 VAL VAL R . n 
A 1 327 LEU 327 271 271 LEU LEU R . n 
A 1 328 LEU 328 272 272 LEU LEU R . n 
A 1 329 ALA 329 273 273 ALA ALA R . n 
A 1 330 ASP 330 274 274 ASP ASP R . n 
A 1 331 THR 331 275 275 THR THR R . n 
A 1 332 LEU 332 276 276 LEU LEU R . n 
A 1 333 MET 333 277 277 MET MET R . n 
A 1 334 ARG 334 278 278 ARG ARG R . n 
A 1 335 THR 335 279 279 THR THR R . n 
A 1 336 GLN 336 280 280 GLN GLN R . n 
A 1 337 VAL 337 281 281 VAL VAL R . n 
A 1 338 ILE 338 282 282 ILE ILE R . n 
A 1 339 GLN 339 283 283 GLN GLN R . n 
A 1 340 GLU 340 284 284 GLU GLU R . n 
A 1 341 THR 341 285 285 THR THR R . n 
A 1 342 CYS 342 286 286 CYS CYS R . n 
A 1 343 GLU 343 287 287 GLU GLU R . n 
A 1 344 ARG 344 288 288 ARG ARG R . n 
A 1 345 ARG 345 289 289 ARG ARG R . n 
A 1 346 ASN 346 290 290 ASN ASN R . n 
A 1 347 HIS 347 291 291 HIS HIS R . n 
A 1 348 ILE 348 292 292 ILE ILE R . n 
A 1 349 ASP 349 293 293 ASP ASP R . n 
A 1 350 ARG 350 294 294 ARG ARG R . n 
A 1 351 ALA 351 295 295 ALA ALA R . n 
A 1 352 LEU 352 296 296 LEU LEU R . n 
A 1 353 ASP 353 297 297 ASP ASP R . n 
A 1 354 ALA 354 298 298 ALA ALA R . n 
A 1 355 THR 355 299 299 THR THR R . n 
A 1 356 GLU 356 300 300 GLU GLU R . n 
A 1 357 ILE 357 301 301 ILE ILE R . n 
A 1 358 LEU 358 302 302 LEU LEU R . n 
A 1 359 GLY 359 303 303 GLY GLY R . n 
A 1 360 ILE 360 304 304 ILE ILE R . n 
A 1 361 LEU 361 305 305 LEU LEU R . n 
A 1 362 HIS 362 306 306 HIS HIS R . n 
A 1 363 SER 363 307 307 SER SER R . n 
A 1 364 CYS 364 308 308 CYS CYS R . n 
A 1 365 LEU 365 309 309 LEU LEU R . n 
A 1 366 ASN 366 310 310 ASN ASN R . n 
A 1 367 PRO 367 311 311 PRO PRO R . n 
A 1 368 LEU 368 312 312 LEU LEU R . n 
A 1 369 ILE 369 313 313 ILE ILE R . n 
A 1 370 TYR 370 314 314 TYR TYR R . n 
A 1 371 ALA 371 315 315 ALA ALA R . n 
A 1 372 PHE 372 316 316 PHE PHE R . n 
A 1 373 ILE 373 317 317 ILE ILE R . n 
A 1 374 GLY 374 318 318 GLY GLY R . n 
A 1 375 GLN 375 319 319 GLN GLN R . n 
A 1 376 LYS 376 320 320 LYS LYS R . n 
A 1 377 PHE 377 321 321 PHE PHE R . n 
A 1 378 ARG 378 322 322 ARG ARG R . n 
A 1 379 HIS 379 323 323 HIS HIS R . n 
A 1 380 GLY 380 324 324 GLY GLY R . n 
A 1 381 LEU 381 325 325 LEU LEU R . n 
A 1 382 LEU 382 326 326 LEU LEU R . n 
A 1 383 LYS 383 327 327 LYS LYS R . n 
A 1 384 ILE 384 328 328 ILE ILE R . n 
A 1 385 LEU 385 329 329 LEU LEU R . n 
A 1 386 ALA 386 330 330 ALA ALA R . n 
A 1 387 ILE 387 331 ?   ?   ?   R . n 
A 1 388 HIS 388 332 ?   ?   ?   R . n 
A 1 389 GLY 389 333 ?   ?   ?   R . n 
A 1 390 LEU 390 334 ?   ?   ?   R . n 
A 1 391 ILE 391 335 ?   ?   ?   R . n 
A 1 392 SER 392 336 ?   ?   ?   R . n 
A 1 393 LYS 393 337 ?   ?   ?   R . n 
A 1 394 ASP 394 338 ?   ?   ?   R . n 
A 1 395 SER 395 339 ?   ?   ?   R . n 
A 1 396 LEU 396 340 ?   ?   ?   R . n 
A 1 397 PRO 397 341 ?   ?   ?   R . n 
A 1 398 LYS 398 342 ?   ?   ?   R . n 
A 1 399 ASP 399 343 ?   ?   ?   R . n 
A 1 400 SER 400 344 ?   ?   ?   R . n 
A 1 401 ARG 401 345 ?   ?   ?   R . n 
A 1 402 PRO 402 346 ?   ?   ?   R . n 
A 1 403 SER 403 347 ?   ?   ?   R . n 
A 1 404 PHE 404 348 ?   ?   ?   R . n 
A 1 405 VAL 405 349 ?   ?   ?   R . n 
A 1 406 GLY 406 350 ?   ?   ?   R . n 
A 1 407 SER 407 351 ?   ?   ?   R . n 
A 1 408 SER 408 352 ?   ?   ?   R . n 
A 1 409 SER 409 353 ?   ?   ?   R . n 
A 1 410 GLY 410 354 ?   ?   ?   R . n 
A 1 411 HIS 411 355 ?   ?   ?   R . n 
A 1 412 THR 412 356 ?   ?   ?   R . n 
A 1 413 SER 413 357 ?   ?   ?   R . n 
A 1 414 THR 414 358 ?   ?   ?   R . n 
A 1 415 THR 415 359 ?   ?   ?   R . n 
A 1 416 LEU 416 360 ?   ?   ?   R . n 
B 2 1   ALA 1   1   1   ALA ALA D . n 
B 2 2   PRO 2   2   2   PRO PRO D . n 
B 2 3   LEU 3   3   3   LEU LEU D . n 
B 2 4   ALA 4   4   4   ALA ALA D . n 
B 2 5   THR 5   5   5   THR THR D . n 
B 2 6   GLU 6   6   6   GLU GLU D . n 
B 2 7   LEU 7   7   7   LEU LEU D . n 
B 2 8   ARG 8   8   8   ARG ARG D . n 
B 2 9   CYS 9   9   9   CYS CYS D . n 
B 2 10  GLN 10  10  10  GLN GLN D . n 
B 2 11  CYS 11  11  11  CYS CYS D . n 
B 2 12  LEU 12  12  12  LEU LEU D . n 
B 2 13  GLN 13  13  13  GLN GLN D . n 
B 2 14  THR 14  14  14  THR THR D . n 
B 2 15  LEU 15  15  15  LEU LEU D . n 
B 2 16  GLN 16  16  16  GLN GLN D . n 
B 2 17  GLY 17  17  17  GLY GLY D . n 
B 2 18  ILE 18  18  18  ILE ILE D . n 
B 2 19  HIS 19  19  19  HIS HIS D . n 
B 2 20  LEU 20  20  20  LEU LEU D . n 
B 2 21  LYS 21  21  21  LYS LYS D . n 
B 2 22  ASN 22  22  22  ASN ASN D . n 
B 2 23  ILE 23  23  23  ILE ILE D . n 
B 2 24  GLN 24  24  24  GLN GLN D . n 
B 2 25  SER 25  25  25  SER SER D . n 
B 2 26  VAL 26  26  26  VAL VAL D . n 
B 2 27  LYS 27  27  27  LYS LYS D . n 
B 2 28  VAL 28  28  28  VAL VAL D . n 
B 2 29  LYS 29  29  29  LYS LYS D . n 
B 2 30  SER 30  30  30  SER SER D . n 
B 2 31  PRO 31  31  31  PRO PRO D . n 
B 2 32  GLY 32  32  32  GLY GLY D . n 
B 2 33  PRO 33  33  33  PRO PRO D . n 
B 2 34  HIS 34  34  34  HIS HIS D . n 
B 2 35  CYS 35  35  35  CYS CYS D . n 
B 2 36  ALA 36  36  36  ALA ALA D . n 
B 2 37  GLN 37  37  37  GLN GLN D . n 
B 2 38  THR 38  38  38  THR THR D . n 
B 2 39  GLU 39  39  39  GLU GLU D . n 
B 2 40  VAL 40  40  40  VAL VAL D . n 
B 2 41  ILE 41  41  41  ILE ILE D . n 
B 2 42  ALA 42  42  42  ALA ALA D . n 
B 2 43  THR 43  43  43  THR THR D . n 
B 2 44  LEU 44  44  44  LEU LEU D . n 
B 2 45  LYS 45  45  45  LYS LYS D . n 
B 2 46  ASN 46  46  46  ASN ASN D . n 
B 2 47  GLY 47  47  47  GLY GLY D . n 
B 2 48  GLN 48  48  48  GLN GLN D . n 
B 2 49  LYS 49  49  49  LYS LYS D . n 
B 2 50  ALA 50  50  50  ALA ALA D . n 
B 2 51  CYS 51  51  51  CYS CYS D . n 
B 2 52  LEU 52  52  52  LEU LEU D . n 
B 2 53  ASN 53  53  53  ASN ASN D . n 
B 2 54  PRO 54  54  54  PRO PRO D . n 
B 2 55  ALA 55  55  55  ALA ALA D . n 
B 2 56  SER 56  56  56  SER SER D . n 
B 2 57  PRO 57  57  57  PRO PRO D . n 
B 2 58  MET 58  58  58  MET MET D . n 
B 2 59  VAL 59  59  59  VAL VAL D . n 
B 2 60  LYS 60  60  60  LYS LYS D . n 
B 2 61  LYS 61  61  61  LYS LYS D . n 
B 2 62  ILE 62  62  62  ILE ILE D . n 
B 2 63  ILE 63  63  63  ILE ILE D . n 
B 2 64  GLU 64  64  64  GLU GLU D . n 
B 2 65  LYS 65  65  65  LYS LYS D . n 
B 2 66  MET 66  66  66  MET MET D . n 
B 2 67  LEU 67  67  67  LEU LEU D . n 
B 2 68  LYS 68  68  68  LYS LYS D . n 
B 2 69  ASN 69  69  69  ASN ASN D . n 
B 2 70  GLY 70  70  ?   ?   ?   D . n 
B 2 71  LYS 71  71  ?   ?   ?   D . n 
B 2 72  SER 72  72  ?   ?   ?   D . n 
B 2 73  ASN 73  73  ?   ?   ?   D . n 
C 2 1   ALA 1   1   ?   ?   ?   E . n 
C 2 2   PRO 2   2   ?   ?   ?   E . n 
C 2 3   LEU 3   3   ?   ?   ?   E . n 
C 2 4   ALA 4   4   ?   ?   ?   E . n 
C 2 5   THR 5   5   ?   ?   ?   E . n 
C 2 6   GLU 6   6   ?   ?   ?   E . n 
C 2 7   LEU 7   7   ?   ?   ?   E . n 
C 2 8   ARG 8   8   ?   ?   ?   E . n 
C 2 9   CYS 9   9   9   CYS CYS E . n 
C 2 10  GLN 10  10  10  GLN GLN E . n 
C 2 11  CYS 11  11  11  CYS CYS E . n 
C 2 12  LEU 12  12  12  LEU LEU E . n 
C 2 13  GLN 13  13  13  GLN GLN E . n 
C 2 14  THR 14  14  14  THR THR E . n 
C 2 15  LEU 15  15  15  LEU LEU E . n 
C 2 16  GLN 16  16  16  GLN GLN E . n 
C 2 17  GLY 17  17  17  GLY GLY E . n 
C 2 18  ILE 18  18  18  ILE ILE E . n 
C 2 19  HIS 19  19  19  HIS HIS E . n 
C 2 20  LEU 20  20  20  LEU LEU E . n 
C 2 21  LYS 21  21  21  LYS LYS E . n 
C 2 22  ASN 22  22  22  ASN ASN E . n 
C 2 23  ILE 23  23  23  ILE ILE E . n 
C 2 24  GLN 24  24  24  GLN GLN E . n 
C 2 25  SER 25  25  25  SER SER E . n 
C 2 26  VAL 26  26  26  VAL VAL E . n 
C 2 27  LYS 27  27  27  LYS LYS E . n 
C 2 28  VAL 28  28  28  VAL VAL E . n 
C 2 29  LYS 29  29  29  LYS LYS E . n 
C 2 30  SER 30  30  30  SER SER E . n 
C 2 31  PRO 31  31  31  PRO PRO E . n 
C 2 32  GLY 32  32  32  GLY GLY E . n 
C 2 33  PRO 33  33  33  PRO PRO E . n 
C 2 34  HIS 34  34  34  HIS HIS E . n 
C 2 35  CYS 35  35  35  CYS CYS E . n 
C 2 36  ALA 36  36  36  ALA ALA E . n 
C 2 37  GLN 37  37  37  GLN GLN E . n 
C 2 38  THR 38  38  38  THR THR E . n 
C 2 39  GLU 39  39  39  GLU GLU E . n 
C 2 40  VAL 40  40  40  VAL VAL E . n 
C 2 41  ILE 41  41  41  ILE ILE E . n 
C 2 42  ALA 42  42  42  ALA ALA E . n 
C 2 43  THR 43  43  43  THR THR E . n 
C 2 44  LEU 44  44  44  LEU LEU E . n 
C 2 45  LYS 45  45  45  LYS LYS E . n 
C 2 46  ASN 46  46  46  ASN ASN E . n 
C 2 47  GLY 47  47  47  GLY GLY E . n 
C 2 48  GLN 48  48  48  GLN GLN E . n 
C 2 49  LYS 49  49  49  LYS LYS E . n 
C 2 50  ALA 50  50  50  ALA ALA E . n 
C 2 51  CYS 51  51  51  CYS CYS E . n 
C 2 52  LEU 52  52  52  LEU LEU E . n 
C 2 53  ASN 53  53  53  ASN ASN E . n 
C 2 54  PRO 54  54  54  PRO PRO E . n 
C 2 55  ALA 55  55  55  ALA ALA E . n 
C 2 56  SER 56  56  56  SER SER E . n 
C 2 57  PRO 57  57  57  PRO PRO E . n 
C 2 58  MET 58  58  58  MET MET E . n 
C 2 59  VAL 59  59  59  VAL VAL E . n 
C 2 60  LYS 60  60  60  LYS LYS E . n 
C 2 61  LYS 61  61  61  LYS LYS E . n 
C 2 62  ILE 62  62  62  ILE ILE E . n 
C 2 63  ILE 63  63  63  ILE ILE E . n 
C 2 64  GLU 64  64  64  GLU GLU E . n 
C 2 65  LYS 65  65  65  LYS LYS E . n 
C 2 66  MET 66  66  66  MET MET E . n 
C 2 67  LEU 67  67  67  LEU LEU E . n 
C 2 68  LYS 68  68  68  LYS LYS E . n 
C 2 69  ASN 69  69  ?   ?   ?   E . n 
C 2 70  GLY 70  70  ?   ?   ?   E . n 
C 2 71  LYS 71  71  ?   ?   ?   E . n 
C 2 72  SER 72  72  ?   ?   ?   E . n 
C 2 73  ASN 73  73  ?   ?   ?   E . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 R GLU 40  ? CG  ? A GLU 96  CG  
2  1 Y 1 R GLU 40  ? CD  ? A GLU 96  CD  
3  1 Y 1 R GLU 40  ? OE1 ? A GLU 96  OE1 
4  1 Y 1 R GLU 40  ? OE2 ? A GLU 96  OE2 
5  1 Y 1 R GLU 45  ? CG  ? A GLU 101 CG  
6  1 Y 1 R GLU 45  ? CD  ? A GLU 101 CD  
7  1 Y 1 R GLU 45  ? OE1 ? A GLU 101 OE1 
8  1 Y 1 R GLU 45  ? OE2 ? A GLU 101 OE2 
9  1 Y 1 R ARG 153 ? CG  ? A ARG 209 CG  
10 1 Y 1 R ARG 153 ? CD  ? A ARG 209 CD  
11 1 Y 1 R ARG 153 ? NE  ? A ARG 209 NE  
12 1 Y 1 R ARG 153 ? CZ  ? A ARG 209 CZ  
13 1 Y 1 R ARG 153 ? NH1 ? A ARG 209 NH1 
14 1 Y 1 R ARG 153 ? NH2 ? A ARG 209 NH2 
15 1 Y 1 R LYS 240 ? CG  ? A LYS 296 CG  
16 1 Y 1 R LYS 240 ? CD  ? A LYS 296 CD  
17 1 Y 1 R LYS 240 ? CE  ? A LYS 296 CE  
18 1 Y 1 R LYS 240 ? NZ  ? A LYS 296 NZ  
19 1 Y 1 D LYS 21  ? CG  ? B LYS 21  CG  
20 1 Y 1 D LYS 21  ? CD  ? B LYS 21  CD  
21 1 Y 1 D LYS 21  ? CE  ? B LYS 21  CE  
22 1 Y 1 D LYS 21  ? NZ  ? B LYS 21  NZ  
23 1 Y 1 D LYS 60  ? CG  ? B LYS 60  CG  
24 1 Y 1 D LYS 60  ? CD  ? B LYS 60  CD  
25 1 Y 1 D LYS 60  ? CE  ? B LYS 60  CE  
26 1 Y 1 D LYS 60  ? NZ  ? B LYS 60  NZ  
27 1 Y 1 D LYS 61  ? CG  ? B LYS 61  CG  
28 1 Y 1 D LYS 61  ? CD  ? B LYS 61  CD  
29 1 Y 1 D LYS 61  ? CE  ? B LYS 61  CE  
30 1 Y 1 D LYS 61  ? NZ  ? B LYS 61  NZ  
31 1 Y 1 D GLU 64  ? CG  ? B GLU 64  CG  
32 1 Y 1 D GLU 64  ? CD  ? B GLU 64  CD  
33 1 Y 1 D GLU 64  ? OE1 ? B GLU 64  OE1 
34 1 Y 1 D GLU 64  ? OE2 ? B GLU 64  OE2 
35 1 Y 1 D LYS 65  ? CG  ? B LYS 65  CG  
36 1 Y 1 D LYS 65  ? CD  ? B LYS 65  CD  
37 1 Y 1 D LYS 65  ? CE  ? B LYS 65  CE  
38 1 Y 1 D LYS 65  ? NZ  ? B LYS 65  NZ  
39 1 Y 1 D LYS 68  ? CG  ? B LYS 68  CG  
40 1 Y 1 D LYS 68  ? CD  ? B LYS 68  CD  
41 1 Y 1 D LYS 68  ? CE  ? B LYS 68  CE  
42 1 Y 1 D LYS 68  ? NZ  ? B LYS 68  NZ  
43 1 Y 1 E LEU 12  ? CG  ? C LEU 12  CG  
44 1 Y 1 E LEU 12  ? CD1 ? C LEU 12  CD1 
45 1 Y 1 E LEU 12  ? CD2 ? C LEU 12  CD2 
46 1 Y 1 E GLN 13  ? CG  ? C GLN 13  CG  
47 1 Y 1 E GLN 13  ? CD  ? C GLN 13  CD  
48 1 Y 1 E GLN 13  ? OE1 ? C GLN 13  OE1 
49 1 Y 1 E GLN 13  ? NE2 ? C GLN 13  NE2 
50 1 Y 1 E LYS 21  ? CG  ? C LYS 21  CG  
51 1 Y 1 E LYS 21  ? CD  ? C LYS 21  CD  
52 1 Y 1 E LYS 21  ? CE  ? C LYS 21  CE  
53 1 Y 1 E LYS 21  ? NZ  ? C LYS 21  NZ  
54 1 Y 1 E GLN 37  ? CG  ? C GLN 37  CG  
55 1 Y 1 E GLN 37  ? CD  ? C GLN 37  CD  
56 1 Y 1 E GLN 37  ? OE1 ? C GLN 37  OE1 
57 1 Y 1 E GLN 37  ? NE2 ? C GLN 37  NE2 
58 1 Y 1 E LYS 60  ? CG  ? C LYS 60  CG  
59 1 Y 1 E LYS 60  ? CD  ? C LYS 60  CD  
60 1 Y 1 E LYS 60  ? CE  ? C LYS 60  CE  
61 1 Y 1 E LYS 60  ? NZ  ? C LYS 60  NZ  
62 1 Y 1 E LYS 61  ? CG  ? C LYS 61  CG  
63 1 Y 1 E LYS 61  ? CD  ? C LYS 61  CD  
64 1 Y 1 E LYS 61  ? CE  ? C LYS 61  CE  
65 1 Y 1 E LYS 61  ? NZ  ? C LYS 61  NZ  
66 1 Y 1 E LYS 65  ? CG  ? C LYS 65  CG  
67 1 Y 1 E LYS 65  ? CD  ? C LYS 65  CD  
68 1 Y 1 E LYS 65  ? CE  ? C LYS 65  CE  
69 1 Y 1 E LYS 65  ? NZ  ? C LYS 65  NZ  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XVU 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XVU 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XVU 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8XVU 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 3420 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.474 ? 4636 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.397 ? 454  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.038 ? 569  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 561  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8XVU 
_struct.title                        'Structure of CXCR2 bound to CXCL2 (Ligand-receptor focused map)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XVU 
_struct_keywords.text            'GPCR, Arrestin, SIGNALING PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP CXCR2_HUMAN P25025 ? 1 
;EDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRS
VTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYL
VKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKA
HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKF
RHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
;
2  
2 UNP CXCL2_HUMAN P19875 ? 2 APLATELRCQCLQTLQGIHLKNIQSVKVKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKNGKSN 35 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XVU R 58 ? 416 ? P25025 2  ? 360 ? 2 360 
2 2 8XVU D 1  ? 73  ? P19875 35 ? 107 ? 1 73  
3 2 8XVU E 1  ? 73  ? P19875 35 ? 107 ? 1 73  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XVU MET R 1  ? UNP P25025 ? ? 'initiating methionine' -55 1  
1 8XVU GLY R 2  ? UNP P25025 ? ? 'expression tag'        -54 2  
1 8XVU LYS R 3  ? UNP P25025 ? ? 'expression tag'        -53 3  
1 8XVU THR R 4  ? UNP P25025 ? ? 'expression tag'        -52 4  
1 8XVU ILE R 5  ? UNP P25025 ? ? 'expression tag'        -51 5  
1 8XVU ILE R 6  ? UNP P25025 ? ? 'expression tag'        -50 6  
1 8XVU ALA R 7  ? UNP P25025 ? ? 'expression tag'        -49 7  
1 8XVU LEU R 8  ? UNP P25025 ? ? 'expression tag'        -48 8  
1 8XVU SER R 9  ? UNP P25025 ? ? 'expression tag'        -47 9  
1 8XVU TYR R 10 ? UNP P25025 ? ? 'expression tag'        -46 10 
1 8XVU ILE R 11 ? UNP P25025 ? ? 'expression tag'        -45 11 
1 8XVU PHE R 12 ? UNP P25025 ? ? 'expression tag'        -44 12 
1 8XVU CYS R 13 ? UNP P25025 ? ? 'expression tag'        -43 13 
1 8XVU LEU R 14 ? UNP P25025 ? ? 'expression tag'        -42 14 
1 8XVU VAL R 15 ? UNP P25025 ? ? 'expression tag'        -41 15 
1 8XVU PHE R 16 ? UNP P25025 ? ? 'expression tag'        -40 16 
1 8XVU ALA R 17 ? UNP P25025 ? ? 'expression tag'        -39 17 
1 8XVU ASP R 18 ? UNP P25025 ? ? 'expression tag'        -38 18 
1 8XVU TYR R 19 ? UNP P25025 ? ? 'expression tag'        -37 19 
1 8XVU LYS R 20 ? UNP P25025 ? ? 'expression tag'        -36 20 
1 8XVU ASP R 21 ? UNP P25025 ? ? 'expression tag'        -35 21 
1 8XVU ASP R 22 ? UNP P25025 ? ? 'expression tag'        -34 22 
1 8XVU ASP R 23 ? UNP P25025 ? ? 'expression tag'        -33 23 
1 8XVU ASP R 24 ? UNP P25025 ? ? 'expression tag'        -32 24 
1 8XVU ALA R 25 ? UNP P25025 ? ? 'expression tag'        -31 25 
1 8XVU ALA R 26 ? UNP P25025 ? ? 'expression tag'        -30 26 
1 8XVU ASN R 27 ? UNP P25025 ? ? 'expression tag'        -29 27 
1 8XVU PHE R 28 ? UNP P25025 ? ? 'expression tag'        -28 28 
1 8XVU THR R 29 ? UNP P25025 ? ? 'expression tag'        -27 29 
1 8XVU PRO R 30 ? UNP P25025 ? ? 'expression tag'        -26 30 
1 8XVU VAL R 31 ? UNP P25025 ? ? 'expression tag'        -25 31 
1 8XVU ASN R 32 ? UNP P25025 ? ? 'expression tag'        -24 32 
1 8XVU GLY R 33 ? UNP P25025 ? ? 'expression tag'        -23 33 
1 8XVU SER R 34 ? UNP P25025 ? ? 'expression tag'        -22 34 
1 8XVU SER R 35 ? UNP P25025 ? ? 'expression tag'        -21 35 
1 8XVU GLY R 36 ? UNP P25025 ? ? 'expression tag'        -20 36 
1 8XVU ASN R 37 ? UNP P25025 ? ? 'expression tag'        -19 37 
1 8XVU GLN R 38 ? UNP P25025 ? ? 'expression tag'        -18 38 
1 8XVU SER R 39 ? UNP P25025 ? ? 'expression tag'        -17 39 
1 8XVU VAL R 40 ? UNP P25025 ? ? 'expression tag'        -16 40 
1 8XVU ARG R 41 ? UNP P25025 ? ? 'expression tag'        -15 41 
1 8XVU LEU R 42 ? UNP P25025 ? ? 'expression tag'        -14 42 
1 8XVU VAL R 43 ? UNP P25025 ? ? 'expression tag'        -13 43 
1 8XVU THR R 44 ? UNP P25025 ? ? 'expression tag'        -12 44 
1 8XVU SER R 45 ? UNP P25025 ? ? 'expression tag'        -11 45 
1 8XVU SER R 46 ? UNP P25025 ? ? 'expression tag'        -10 46 
1 8XVU SER R 47 ? UNP P25025 ? ? 'expression tag'        -9  47 
1 8XVU LEU R 48 ? UNP P25025 ? ? 'expression tag'        -8  48 
1 8XVU GLU R 49 ? UNP P25025 ? ? 'expression tag'        -7  49 
1 8XVU VAL R 50 ? UNP P25025 ? ? 'expression tag'        -6  50 
1 8XVU LEU R 51 ? UNP P25025 ? ? 'expression tag'        -5  51 
1 8XVU PHE R 52 ? UNP P25025 ? ? 'expression tag'        -4  52 
1 8XVU GLN R 53 ? UNP P25025 ? ? 'expression tag'        -3  53 
1 8XVU GLY R 54 ? UNP P25025 ? ? 'expression tag'        -2  54 
1 8XVU PRO R 55 ? UNP P25025 ? ? 'expression tag'        -1  55 
1 8XVU GLY R 56 ? UNP P25025 ? ? 'expression tag'        0   56 
1 8XVU SER R 57 ? UNP P25025 ? ? 'expression tag'        1   57 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 100 ? SER A 132 ? LEU R 44  SER R 76  1 ? 33 
HELX_P HELX_P2  AA2 SER A 137 ? GLY A 167 ? SER R 81  GLY R 111 1 ? 31 
HELX_P HELX_P3  AA3 GLY A 171 ? VAL A 205 ? GLY R 115 VAL R 149 1 ? 35 
HELX_P HELX_P4  AA4 ARG A 209 ? TYR A 216 ? ARG R 153 TYR R 160 5 ? 8  
HELX_P HELX_P5  AA5 LEU A 217 ? ALA A 233 ? LEU R 161 ALA R 177 1 ? 17 
HELX_P HELX_P6  AA6 ALA A 233 ? PHE A 239 ? ALA R 177 PHE R 183 1 ? 7  
HELX_P HELX_P7  AA7 ASN A 259 ? ARG A 268 ? ASN R 203 ARG R 212 1 ? 10 
HELX_P HELX_P8  AA8 ARG A 268 ? PHE A 274 ? ARG R 212 PHE R 218 1 ? 7  
HELX_P HELX_P9  AA9 PHE A 276 ? LYS A 296 ? PHE R 220 LYS R 240 1 ? 21 
HELX_P HELX_P10 AB1 GLN A 301 ? THR A 335 ? GLN R 245 THR R 279 1 ? 35 
HELX_P HELX_P11 AB2 THR A 341 ? ILE A 360 ? THR R 285 ILE R 304 1 ? 20 
HELX_P HELX_P12 AB3 LEU A 361 ? ALA A 371 ? LEU R 305 ALA R 315 1 ? 11 
HELX_P HELX_P13 AB4 GLY A 374 ? ALA A 386 ? GLY R 318 ALA R 330 1 ? 13 
HELX_P HELX_P14 AB5 HIS B 19  ? LYS B 21  ? HIS D 19  LYS D 21  5 ? 3  
HELX_P HELX_P15 AB6 SER B 56  ? ASN B 69  ? SER D 56  ASN D 69  1 ? 14 
HELX_P HELX_P16 AB7 SER C 56  ? LYS C 68  ? SER E 56  LYS E 68  1 ? 13 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 95  SG ? ? ? 1_555 A CYS 342 SG ? ? R CYS 39  R CYS 286 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? A CYS 175 SG ? ? ? 1_555 A CYS 252 SG ? ? R CYS 119 R CYS 196 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf3 disulf ? ? B CYS 9   SG ? ? ? 1_555 B CYS 35  SG ? ? D CYS 9   D CYS 35  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf4 disulf ? ? B CYS 11  SG ? ? ? 1_555 B CYS 51  SG ? ? D CYS 11  D CYS 51  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf5 disulf ? ? C CYS 9   SG ? ? ? 1_555 C CYS 35  SG ? ? E CYS 9   E CYS 35  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf6 disulf ? ? C CYS 11  SG ? ? ? 1_555 C CYS 51  SG ? ? E CYS 11  E CYS 51  1_555 ? ? ? ? ? ? ? 2.027 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 95  ? CYS A 342 ? CYS R 39  ? 1_555 CYS R 286 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 175 ? CYS A 252 ? CYS R 119 ? 1_555 CYS R 196 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS B 9   ? CYS B 35  ? CYS D 9   ? 1_555 CYS D 35  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 11  ? CYS B 51  ? CYS D 11  ? 1_555 CYS D 51  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5 CYS C 9   ? CYS C 35  ? CYS E 9   ? 1_555 CYS E 35  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6 CYS C 11  ? CYS C 51  ? CYS E 11  ? 1_555 CYS E 51  ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 240 ? VAL A 243 ? ARG R 184 VAL R 187 
AA1 2 ALA A 251 ? GLU A 254 ? ALA R 195 GLU R 198 
AA2 1 LYS B 49  ? LEU B 52  ? LYS D 49  LEU D 52  
AA2 2 GLU B 39  ? LEU B 44  ? GLU D 39  LEU D 44  
AA2 3 ILE B 23  ? LYS B 29  ? ILE D 23  LYS D 29  
AA2 4 ILE C 23  ? LYS C 29  ? ILE E 23  LYS E 29  
AA2 5 GLU C 39  ? LEU C 44  ? GLU E 39  LEU E 44  
AA2 6 LYS C 49  ? LEU C 52  ? LYS E 49  LEU E 52  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 243 ? N VAL R 187 O ALA A 251 ? O ALA R 195 
AA2 1 2 O ALA B 50  ? O ALA D 50  N ALA B 42  ? N ALA D 42  
AA2 2 3 O GLU B 39  ? O GLU D 39  N LYS B 29  ? N LYS D 29  
AA2 3 4 N VAL B 26  ? N VAL D 26  O VAL C 28  ? O VAL E 28  
AA2 4 5 N GLN C 24  ? N GLN E 24  O THR C 43  ? O THR E 43  
AA2 5 6 N ALA C 42  ? N ALA E 42  O ALA C 50  ? O ALA E 50  
# 
_pdbx_entry_details.entry_id                   8XVU 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 HIS R 150 ? ? -92.85  54.30  
2 1 LEU R 161 ? ? -97.53  33.22  
3 1 PHE R 220 ? ? -120.67 -55.15 
4 1 ALA D 4   ? ? -170.20 140.44 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8XVU 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   SwissModel 
_em_3d_fitting_list.type                          'in silico model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    8XVU 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.09 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               285884 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
loop_
_em_entity_assembly.id 
_em_entity_assembly.parent_id 
_em_entity_assembly.source 
_em_entity_assembly.type 
_em_entity_assembly.name 
_em_entity_assembly.details 
_em_entity_assembly.synonym 
_em_entity_assembly.oligomeric_details 
_em_entity_assembly.entity_id_list 
1 0 RECOMBINANT COMPLEX 'C-X-C chemokine receptor type 2 in complex with C-X-C motif chemokine 2' ? ? ? 1,2 
2 1 RECOMBINANT COMPLEX 'C-X-C chemokine receptor type 2'                                         ? ? ? 1   
3 1 RECOMBINANT COMPLEX 'C-X-C motif chemokine 2'                                                 ? ? ? 2   
# 
_em_image_scans.entry_id                8XVU 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        ? 
_em_image_scans.dimension_width         ? 
_em_image_scans.frames_per_image        40 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   ? 
# 
_em_imaging.entry_id                        8XVU 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_vitrification.entry_id              8XVU 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8XVU 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 R MET -55 ? A MET 1   
2   1 Y 1 R GLY -54 ? A GLY 2   
3   1 Y 1 R LYS -53 ? A LYS 3   
4   1 Y 1 R THR -52 ? A THR 4   
5   1 Y 1 R ILE -51 ? A ILE 5   
6   1 Y 1 R ILE -50 ? A ILE 6   
7   1 Y 1 R ALA -49 ? A ALA 7   
8   1 Y 1 R LEU -48 ? A LEU 8   
9   1 Y 1 R SER -47 ? A SER 9   
10  1 Y 1 R TYR -46 ? A TYR 10  
11  1 Y 1 R ILE -45 ? A ILE 11  
12  1 Y 1 R PHE -44 ? A PHE 12  
13  1 Y 1 R CYS -43 ? A CYS 13  
14  1 Y 1 R LEU -42 ? A LEU 14  
15  1 Y 1 R VAL -41 ? A VAL 15  
16  1 Y 1 R PHE -40 ? A PHE 16  
17  1 Y 1 R ALA -39 ? A ALA 17  
18  1 Y 1 R ASP -38 ? A ASP 18  
19  1 Y 1 R TYR -37 ? A TYR 19  
20  1 Y 1 R LYS -36 ? A LYS 20  
21  1 Y 1 R ASP -35 ? A ASP 21  
22  1 Y 1 R ASP -34 ? A ASP 22  
23  1 Y 1 R ASP -33 ? A ASP 23  
24  1 Y 1 R ASP -32 ? A ASP 24  
25  1 Y 1 R ALA -31 ? A ALA 25  
26  1 Y 1 R ALA -30 ? A ALA 26  
27  1 Y 1 R ASN -29 ? A ASN 27  
28  1 Y 1 R PHE -28 ? A PHE 28  
29  1 Y 1 R THR -27 ? A THR 29  
30  1 Y 1 R PRO -26 ? A PRO 30  
31  1 Y 1 R VAL -25 ? A VAL 31  
32  1 Y 1 R ASN -24 ? A ASN 32  
33  1 Y 1 R GLY -23 ? A GLY 33  
34  1 Y 1 R SER -22 ? A SER 34  
35  1 Y 1 R SER -21 ? A SER 35  
36  1 Y 1 R GLY -20 ? A GLY 36  
37  1 Y 1 R ASN -19 ? A ASN 37  
38  1 Y 1 R GLN -18 ? A GLN 38  
39  1 Y 1 R SER -17 ? A SER 39  
40  1 Y 1 R VAL -16 ? A VAL 40  
41  1 Y 1 R ARG -15 ? A ARG 41  
42  1 Y 1 R LEU -14 ? A LEU 42  
43  1 Y 1 R VAL -13 ? A VAL 43  
44  1 Y 1 R THR -12 ? A THR 44  
45  1 Y 1 R SER -11 ? A SER 45  
46  1 Y 1 R SER -10 ? A SER 46  
47  1 Y 1 R SER -9  ? A SER 47  
48  1 Y 1 R LEU -8  ? A LEU 48  
49  1 Y 1 R GLU -7  ? A GLU 49  
50  1 Y 1 R VAL -6  ? A VAL 50  
51  1 Y 1 R LEU -5  ? A LEU 51  
52  1 Y 1 R PHE -4  ? A PHE 52  
53  1 Y 1 R GLN -3  ? A GLN 53  
54  1 Y 1 R GLY -2  ? A GLY 54  
55  1 Y 1 R PRO -1  ? A PRO 55  
56  1 Y 1 R GLY 0   ? A GLY 56  
57  1 Y 1 R SER 1   ? A SER 57  
58  1 Y 1 R GLU 2   ? A GLU 58  
59  1 Y 1 R ASP 3   ? A ASP 59  
60  1 Y 1 R PHE 4   ? A PHE 60  
61  1 Y 1 R ASN 5   ? A ASN 61  
62  1 Y 1 R MET 6   ? A MET 62  
63  1 Y 1 R GLU 7   ? A GLU 63  
64  1 Y 1 R SER 8   ? A SER 64  
65  1 Y 1 R ASP 9   ? A ASP 65  
66  1 Y 1 R SER 10  ? A SER 66  
67  1 Y 1 R PHE 11  ? A PHE 67  
68  1 Y 1 R GLU 12  ? A GLU 68  
69  1 Y 1 R ASP 13  ? A ASP 69  
70  1 Y 1 R PHE 14  ? A PHE 70  
71  1 Y 1 R TRP 15  ? A TRP 71  
72  1 Y 1 R LYS 16  ? A LYS 72  
73  1 Y 1 R GLY 17  ? A GLY 73  
74  1 Y 1 R GLU 18  ? A GLU 74  
75  1 Y 1 R ASP 19  ? A ASP 75  
76  1 Y 1 R LEU 20  ? A LEU 76  
77  1 Y 1 R SER 21  ? A SER 77  
78  1 Y 1 R ASN 22  ? A ASN 78  
79  1 Y 1 R TYR 23  ? A TYR 79  
80  1 Y 1 R SER 24  ? A SER 80  
81  1 Y 1 R TYR 25  ? A TYR 81  
82  1 Y 1 R SER 26  ? A SER 82  
83  1 Y 1 R SER 27  ? A SER 83  
84  1 Y 1 R THR 28  ? A THR 84  
85  1 Y 1 R LEU 29  ? A LEU 85  
86  1 Y 1 R PRO 30  ? A PRO 86  
87  1 Y 1 R PRO 31  ? A PRO 87  
88  1 Y 1 R PHE 32  ? A PHE 88  
89  1 Y 1 R ILE 331 ? A ILE 387 
90  1 Y 1 R HIS 332 ? A HIS 388 
91  1 Y 1 R GLY 333 ? A GLY 389 
92  1 Y 1 R LEU 334 ? A LEU 390 
93  1 Y 1 R ILE 335 ? A ILE 391 
94  1 Y 1 R SER 336 ? A SER 392 
95  1 Y 1 R LYS 337 ? A LYS 393 
96  1 Y 1 R ASP 338 ? A ASP 394 
97  1 Y 1 R SER 339 ? A SER 395 
98  1 Y 1 R LEU 340 ? A LEU 396 
99  1 Y 1 R PRO 341 ? A PRO 397 
100 1 Y 1 R LYS 342 ? A LYS 398 
101 1 Y 1 R ASP 343 ? A ASP 399 
102 1 Y 1 R SER 344 ? A SER 400 
103 1 Y 1 R ARG 345 ? A ARG 401 
104 1 Y 1 R PRO 346 ? A PRO 402 
105 1 Y 1 R SER 347 ? A SER 403 
106 1 Y 1 R PHE 348 ? A PHE 404 
107 1 Y 1 R VAL 349 ? A VAL 405 
108 1 Y 1 R GLY 350 ? A GLY 406 
109 1 Y 1 R SER 351 ? A SER 407 
110 1 Y 1 R SER 352 ? A SER 408 
111 1 Y 1 R SER 353 ? A SER 409 
112 1 Y 1 R GLY 354 ? A GLY 410 
113 1 Y 1 R HIS 355 ? A HIS 411 
114 1 Y 1 R THR 356 ? A THR 412 
115 1 Y 1 R SER 357 ? A SER 413 
116 1 Y 1 R THR 358 ? A THR 414 
117 1 Y 1 R THR 359 ? A THR 415 
118 1 Y 1 R LEU 360 ? A LEU 416 
119 1 Y 1 D GLY 70  ? B GLY 70  
120 1 Y 1 D LYS 71  ? B LYS 71  
121 1 Y 1 D SER 72  ? B SER 72  
122 1 Y 1 D ASN 73  ? B ASN 73  
123 1 Y 1 E ALA 1   ? C ALA 1   
124 1 Y 1 E PRO 2   ? C PRO 2   
125 1 Y 1 E LEU 3   ? C LEU 3   
126 1 Y 1 E ALA 4   ? C ALA 4   
127 1 Y 1 E THR 5   ? C THR 5   
128 1 Y 1 E GLU 6   ? C GLU 6   
129 1 Y 1 E LEU 7   ? C LEU 7   
130 1 Y 1 E ARG 8   ? C ARG 8   
131 1 Y 1 E ASN 69  ? C ASN 69  
132 1 Y 1 E GLY 70  ? C GLY 70  
133 1 Y 1 E LYS 71  ? C LYS 71  
134 1 Y 1 E SER 72  ? C SER 72  
135 1 Y 1 E ASN 73  ? C ASN 73  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-15 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8XVU 
_em_admin.last_update        2025-04-09 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'Structure of CXCR2 bound to CXCL2 (Ligand-receptor focused map)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
loop_
_em_entity_assembly_molwt.entity_assembly_id 
_em_entity_assembly_molwt.experimental_flag 
_em_entity_assembly_molwt.id 
_em_entity_assembly_molwt.units 
_em_entity_assembly_molwt.value 
1 NO 1 ? ? 
1 NO 2 ? ? 
# 
loop_
_em_entity_assembly_naturalsource.cell 
_em_entity_assembly_naturalsource.cellular_location 
_em_entity_assembly_naturalsource.entity_assembly_id 
_em_entity_assembly_naturalsource.id 
_em_entity_assembly_naturalsource.ncbi_tax_id 
_em_entity_assembly_naturalsource.organism 
_em_entity_assembly_naturalsource.organelle 
_em_entity_assembly_naturalsource.organ 
_em_entity_assembly_naturalsource.strain 
_em_entity_assembly_naturalsource.tissue 
_em_entity_assembly_naturalsource.details 
? ? 1 2 9606 'Homo sapiens' ? ? ? ? ? 
? ? 2 3 9606 'Homo sapiens' ? ? ? ? ? 
# 
loop_
_em_entity_assembly_recombinant.cell 
_em_entity_assembly_recombinant.entity_assembly_id 
_em_entity_assembly_recombinant.id 
_em_entity_assembly_recombinant.ncbi_tax_id 
_em_entity_assembly_recombinant.organism 
_em_entity_assembly_recombinant.plasmid 
_em_entity_assembly_recombinant.strain 
? 1 2 7108 'Spodoptera frugiperda' ? ? 
? 2 3 7108 'Spodoptera frugiperda' ? ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.2 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1927680 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ?   
MASKING                    ? 3  ? ? ? ?         ?   
'CTF CORRECTION'           ? 4  1 ? ? cryoSPARC 4.4 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?   
'MODEL FITTING'            ? 7  ? 1 ? Coot      ?   
OTHER                      ? 8  ? ? ? ?         ?   
'MODEL REFINEMENT'         ? 9  ? 1 ? PHENIX    ?   
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?         ?   
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?         ?   
CLASSIFICATION             ? 12 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION             ? 13 1 ? ? cryoSPARC 4.4 
RECONSTRUCTION             ? 14 1 ? ? RELION    4   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Science and Engineering Research Board (SERB)' 
_pdbx_audit_support.country                India 
_pdbx_audit_support.grant_number           IPA/2020/000405 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      SwissModel 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    8XVU 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . LEU A 1 89  ? 119.767 135.878 54.460  1.00 100.69 ? 33  LEU R N   1 
ATOM 2    C CA  . LEU A 1 89  ? 118.852 136.458 55.435  1.00 100.69 ? 33  LEU R CA  1 
ATOM 3    C C   . LEU A 1 89  ? 118.755 135.566 56.666  1.00 100.69 ? 33  LEU R C   1 
ATOM 4    O O   . LEU A 1 89  ? 118.778 136.049 57.798  1.00 100.69 ? 33  LEU R O   1 
ATOM 5    C CB  . LEU A 1 89  ? 117.466 136.660 54.818  1.00 100.69 ? 33  LEU R CB  1 
ATOM 6    C CG  . LEU A 1 89  ? 117.328 137.749 53.750  1.00 100.69 ? 33  LEU R CG  1 
ATOM 7    C CD1 . LEU A 1 89  ? 115.862 137.982 53.433  1.00 100.69 ? 33  LEU R CD1 1 
ATOM 8    C CD2 . LEU A 1 89  ? 117.992 139.050 54.176  1.00 100.69 ? 33  LEU R CD2 1 
ATOM 9    N N   . LEU A 1 90  ? 118.646 134.256 56.437  1.00 104.52 ? 34  LEU R N   1 
ATOM 10   C CA  . LEU A 1 90  ? 118.621 133.312 57.547  1.00 104.52 ? 34  LEU R CA  1 
ATOM 11   C C   . LEU A 1 90  ? 119.896 133.380 58.373  1.00 104.52 ? 34  LEU R C   1 
ATOM 12   O O   . LEU A 1 90  ? 119.882 133.003 59.550  1.00 104.52 ? 34  LEU R O   1 
ATOM 13   C CB  . LEU A 1 90  ? 118.415 131.891 57.021  1.00 104.52 ? 34  LEU R CB  1 
ATOM 14   C CG  . LEU A 1 90  ? 117.970 130.855 58.054  1.00 104.52 ? 34  LEU R CG  1 
ATOM 15   C CD1 . LEU A 1 90  ? 116.484 130.992 58.348  1.00 104.52 ? 34  LEU R CD1 1 
ATOM 16   C CD2 . LEU A 1 90  ? 118.296 129.448 57.576  1.00 104.52 ? 34  LEU R CD2 1 
ATOM 17   N N   . ASP A 1 91  ? 120.996 133.852 57.783  1.00 106.21 ? 35  ASP R N   1 
ATOM 18   C CA  . ASP A 1 91  ? 122.232 134.016 58.539  1.00 106.21 ? 35  ASP R CA  1 
ATOM 19   C C   . ASP A 1 91  ? 122.047 135.003 59.683  1.00 106.21 ? 35  ASP R C   1 
ATOM 20   O O   . ASP A 1 91  ? 122.708 134.893 60.722  1.00 106.21 ? 35  ASP R O   1 
ATOM 21   C CB  . ASP A 1 91  ? 123.354 134.479 57.608  1.00 106.21 ? 35  ASP R CB  1 
ATOM 22   C CG  . ASP A 1 91  ? 124.728 134.055 58.090  1.00 106.21 ? 35  ASP R CG  1 
ATOM 23   O OD1 . ASP A 1 91  ? 124.824 133.469 59.188  1.00 106.21 ? 35  ASP R OD1 1 
ATOM 24   O OD2 . ASP A 1 91  ? 125.715 134.312 57.369  1.00 106.21 ? 35  ASP R OD2 1 
ATOM 25   N N   . ALA A 1 92  ? 121.153 135.974 59.509  1.00 96.05  ? 36  ALA R N   1 
ATOM 26   C CA  . ALA A 1 92  ? 120.884 136.996 60.515  1.00 96.05  ? 36  ALA R CA  1 
ATOM 27   C C   . ALA A 1 92  ? 119.387 137.020 60.789  1.00 96.05  ? 36  ALA R C   1 
ATOM 28   O O   . ALA A 1 92  ? 118.641 137.734 60.113  1.00 96.05  ? 36  ALA R O   1 
ATOM 29   C CB  . ALA A 1 92  ? 121.374 138.368 60.054  1.00 96.05  ? 36  ALA R CB  1 
ATOM 30   N N   . ALA A 1 93  ? 118.951 136.236 61.772  1.00 84.08  ? 37  ALA R N   1 
ATOM 31   C CA  . ALA A 1 93  ? 117.568 136.220 62.198  1.00 84.08  ? 37  ALA R CA  1 
ATOM 32   C C   . ALA A 1 93  ? 117.538 136.170 63.719  1.00 84.08  ? 37  ALA R C   1 
ATOM 33   O O   . ALA A 1 93  ? 118.473 135.642 64.338  1.00 84.08  ? 37  ALA R O   1 
ATOM 34   C CB  . ALA A 1 93  ? 116.804 135.022 61.621  1.00 84.08  ? 37  ALA R CB  1 
ATOM 35   N N   . PRO A 1 94  ? 116.494 136.705 64.348  1.00 85.34  ? 38  PRO R N   1 
ATOM 36   C CA  . PRO A 1 94  ? 116.441 136.696 65.812  1.00 85.34  ? 38  PRO R CA  1 
ATOM 37   C C   . PRO A 1 94  ? 116.432 135.278 66.364  1.00 85.34  ? 38  PRO R C   1 
ATOM 38   O O   . PRO A 1 94  ? 115.883 134.357 65.757  1.00 85.34  ? 38  PRO R O   1 
ATOM 39   C CB  . PRO A 1 94  ? 115.128 137.423 66.124  1.00 85.34  ? 38  PRO R CB  1 
ATOM 40   C CG  . PRO A 1 94  ? 114.838 138.228 64.914  1.00 85.34  ? 38  PRO R CG  1 
ATOM 41   C CD  . PRO A 1 94  ? 115.356 137.433 63.764  1.00 85.34  ? 38  PRO R CD  1 
ATOM 42   N N   . CYS A 1 95  ? 117.050 135.109 67.530  1.00 100.23 ? 39  CYS R N   1 
ATOM 43   C CA  . CYS A 1 95  ? 116.985 133.842 68.247  1.00 100.23 ? 39  CYS R CA  1 
ATOM 44   C C   . CYS A 1 95  ? 115.625 133.731 68.924  1.00 100.23 ? 39  CYS R C   1 
ATOM 45   O O   . CYS A 1 95  ? 115.264 134.581 69.744  1.00 100.23 ? 39  CYS R O   1 
ATOM 46   C CB  . CYS A 1 95  ? 118.104 133.743 69.283  1.00 100.23 ? 39  CYS R CB  1 
ATOM 47   S SG  . CYS A 1 95  ? 119.721 133.167 68.683  1.00 100.23 ? 39  CYS R SG  1 
ATOM 48   N N   . GLU A 1 96  ? 114.874 132.694 68.582  1.00 101.02 ? 40  GLU R N   1 
ATOM 49   C CA  . GLU A 1 96  ? 113.554 132.502 69.173  1.00 101.02 ? 40  GLU R CA  1 
ATOM 50   C C   . GLU A 1 96  ? 113.670 131.676 70.449  1.00 101.02 ? 40  GLU R C   1 
ATOM 51   O O   . GLU A 1 96  ? 114.180 130.552 70.403  1.00 101.02 ? 40  GLU R O   1 
ATOM 52   C CB  . GLU A 1 96  ? 112.612 131.836 68.182  1.00 30.00  ? 40  GLU R CB  1 
ATOM 53   N N   . PRO A 1 97  ? 113.220 132.181 71.598  1.00 98.73  ? 41  PRO R N   1 
ATOM 54   C CA  . PRO A 1 97  ? 113.295 131.378 72.821  1.00 98.73  ? 41  PRO R CA  1 
ATOM 55   C C   . PRO A 1 97  ? 112.443 130.125 72.711  1.00 98.73  ? 41  PRO R C   1 
ATOM 56   O O   . PRO A 1 97  ? 111.394 130.111 72.064  1.00 98.73  ? 41  PRO R O   1 
ATOM 57   C CB  . PRO A 1 97  ? 112.764 132.324 73.904  1.00 98.73  ? 41  PRO R CB  1 
ATOM 58   C CG  . PRO A 1 97  ? 111.919 133.296 73.176  1.00 98.73  ? 41  PRO R CG  1 
ATOM 59   C CD  . PRO A 1 97  ? 112.559 133.475 71.835  1.00 98.73  ? 41  PRO R CD  1 
ATOM 60   N N   . GLU A 1 98  ? 112.910 129.062 73.358  1.00 106.17 ? 42  GLU R N   1 
ATOM 61   C CA  . GLU A 1 98  ? 112.272 127.754 73.294  1.00 106.17 ? 42  GLU R CA  1 
ATOM 62   C C   . GLU A 1 98  ? 111.730 127.384 74.667  1.00 106.17 ? 42  GLU R C   1 
ATOM 63   O O   . GLU A 1 98  ? 112.418 127.559 75.678  1.00 106.17 ? 42  GLU R O   1 
ATOM 64   C CB  . GLU A 1 98  ? 113.261 126.692 72.808  1.00 106.17 ? 42  GLU R CB  1 
ATOM 65   C CG  . GLU A 1 98  ? 112.696 125.755 71.753  1.00 106.17 ? 42  GLU R CG  1 
ATOM 66   C CD  . GLU A 1 98  ? 113.778 125.116 70.903  1.00 106.17 ? 42  GLU R CD  1 
ATOM 67   O OE1 . GLU A 1 98  ? 114.542 125.861 70.254  1.00 106.17 ? 42  GLU R OE1 1 
ATOM 68   O OE2 . GLU A 1 98  ? 113.863 123.870 70.881  1.00 106.17 ? 42  GLU R OE2 1 
ATOM 69   N N   . SER A 1 99  ? 110.499 126.879 74.698  1.00 110.35 ? 43  SER R N   1 
ATOM 70   C CA  . SER A 1 99  ? 109.841 126.482 75.934  1.00 110.35 ? 43  SER R CA  1 
ATOM 71   C C   . SER A 1 99  ? 109.169 125.130 75.741  1.00 110.35 ? 43  SER R C   1 
ATOM 72   O O   . SER A 1 99  ? 109.070 124.615 74.625  1.00 110.35 ? 43  SER R O   1 
ATOM 73   C CB  . SER A 1 99  ? 108.802 127.518 76.378  1.00 110.35 ? 43  SER R CB  1 
ATOM 74   O OG  . SER A 1 99  ? 107.566 127.309 75.718  1.00 110.35 ? 43  SER R OG  1 
ATOM 75   N N   . LEU A 1 100 ? 108.705 124.559 76.852  1.00 112.76 ? 44  LEU R N   1 
ATOM 76   C CA  . LEU A 1 100 ? 108.024 123.266 76.842  1.00 112.76 ? 44  LEU R CA  1 
ATOM 77   C C   . LEU A 1 100 ? 107.088 123.208 78.041  1.00 112.76 ? 44  LEU R C   1 
ATOM 78   O O   . LEU A 1 100 ? 107.546 123.059 79.178  1.00 112.76 ? 44  LEU R O   1 
ATOM 79   C CB  . LEU A 1 100 ? 109.029 122.115 76.880  1.00 112.76 ? 44  LEU R CB  1 
ATOM 80   C CG  . LEU A 1 100 ? 109.797 121.828 75.587  1.00 112.76 ? 44  LEU R CG  1 
ATOM 81   C CD1 . LEU A 1 100 ? 110.791 120.697 75.804  1.00 112.76 ? 44  LEU R CD1 1 
ATOM 82   C CD2 . LEU A 1 100 ? 108.850 121.493 74.443  1.00 112.76 ? 44  LEU R CD2 1 
ATOM 83   N N   . GLU A 1 101 ? 105.780 123.312 77.789  1.00 112.54 ? 45  GLU R N   1 
ATOM 84   C CA  . GLU A 1 101 ? 104.800 123.232 78.867  1.00 112.54 ? 45  GLU R CA  1 
ATOM 85   C C   . GLU A 1 101 ? 104.862 121.886 79.575  1.00 112.54 ? 45  GLU R C   1 
ATOM 86   O O   . GLU A 1 101 ? 104.492 121.785 80.756  1.00 112.54 ? 45  GLU R O   1 
ATOM 87   C CB  . GLU A 1 101 ? 103.400 123.484 78.329  1.00 30.00  ? 45  GLU R CB  1 
ATOM 88   N N   . ILE A 1 102 ? 105.332 120.847 78.880  1.00 111.01 ? 46  ILE R N   1 
ATOM 89   C CA  . ILE A 1 102 ? 105.446 119.526 79.488  1.00 111.01 ? 46  ILE R CA  1 
ATOM 90   C C   . ILE A 1 102 ? 106.262 119.609 80.769  1.00 111.01 ? 46  ILE R C   1 
ATOM 91   O O   . ILE A 1 102 ? 105.911 119.003 81.788  1.00 111.01 ? 46  ILE R O   1 
ATOM 92   C CB  . ILE A 1 102 ? 106.064 118.532 78.487  1.00 111.01 ? 46  ILE R CB  1 
ATOM 93   C CG1 . ILE A 1 102 ? 105.184 118.410 77.239  1.00 111.01 ? 46  ILE R CG1 1 
ATOM 94   C CG2 . ILE A 1 102 ? 106.248 117.171 79.136  1.00 111.01 ? 46  ILE R CG2 1 
ATOM 95   C CD1 . ILE A 1 102 ? 105.899 117.817 76.047  1.00 111.01 ? 46  ILE R CD1 1 
ATOM 96   N N   . ASN A 1 103 ? 107.361 120.360 80.740  1.00 107.24 ? 47  ASN R N   1 
ATOM 97   C CA  . ASN A 1 103 ? 108.150 120.592 81.940  1.00 107.24 ? 47  ASN R CA  1 
ATOM 98   C C   . ASN A 1 103 ? 107.584 121.702 82.815  1.00 107.24 ? 47  ASN R C   1 
ATOM 99   O O   . ASN A 1 103 ? 107.801 121.680 84.030  1.00 107.24 ? 47  ASN R O   1 
ATOM 100  C CB  . ASN A 1 103 ? 109.596 120.933 81.567  1.00 107.24 ? 47  ASN R CB  1 
ATOM 101  C CG  . ASN A 1 103 ? 110.147 120.027 80.489  1.00 107.24 ? 47  ASN R CG  1 
ATOM 102  O OD1 . ASN A 1 103 ? 110.125 118.803 80.620  1.00 107.24 ? 47  ASN R OD1 1 
ATOM 103  N ND2 . ASN A 1 103 ? 110.650 120.623 79.415  1.00 107.24 ? 47  ASN R ND2 1 
ATOM 104  N N   . LYS A 1 104 ? 106.865 122.666 82.237  1.00 105.01 ? 48  LYS R N   1 
ATOM 105  C CA  . LYS A 1 104 ? 106.311 123.746 83.048  1.00 105.01 ? 48  LYS R CA  1 
ATOM 106  C C   . LYS A 1 104 ? 105.338 123.201 84.083  1.00 105.01 ? 48  LYS R C   1 
ATOM 107  O O   . LYS A 1 104 ? 105.364 123.606 85.250  1.00 105.01 ? 48  LYS R O   1 
ATOM 108  C CB  . LYS A 1 104 ? 105.619 124.780 82.160  1.00 105.01 ? 48  LYS R CB  1 
ATOM 109  C CG  . LYS A 1 104 ? 106.541 125.495 81.187  1.00 105.01 ? 48  LYS R CG  1 
ATOM 110  C CD  . LYS A 1 104 ? 105.780 126.523 80.364  1.00 105.01 ? 48  LYS R CD  1 
ATOM 111  C CE  . LYS A 1 104 ? 106.625 127.075 79.227  1.00 105.01 ? 48  LYS R CE  1 
ATOM 112  N NZ  . LYS A 1 104 ? 105.893 128.105 78.441  1.00 105.01 ? 48  LYS R NZ  1 
ATOM 113  N N   . TYR A 1 105 ? 104.469 122.274 83.674  1.00 99.82  ? 49  TYR R N   1 
ATOM 114  C CA  . TYR A 1 105 ? 103.502 121.722 84.620  1.00 99.82  ? 49  TYR R CA  1 
ATOM 115  C C   . TYR A 1 105 ? 104.149 120.724 85.576  1.00 99.82  ? 49  TYR R C   1 
ATOM 116  O O   . TYR A 1 105 ? 103.660 120.535 86.694  1.00 99.82  ? 49  TYR R O   1 
ATOM 117  C CB  . TYR A 1 105 ? 102.346 121.067 83.863  1.00 99.82  ? 49  TYR R CB  1 
ATOM 118  C CG  . TYR A 1 105 ? 101.160 120.713 84.733  1.00 99.82  ? 49  TYR R CG  1 
ATOM 119  C CD1 . TYR A 1 105 ? 100.661 121.613 85.666  1.00 99.82  ? 49  TYR R CD1 1 
ATOM 120  C CD2 . TYR A 1 105 ? 100.533 119.480 84.614  1.00 99.82  ? 49  TYR R CD2 1 
ATOM 121  C CE1 . TYR A 1 105 ? 99.578  121.291 86.462  1.00 99.82  ? 49  TYR R CE1 1 
ATOM 122  C CE2 . TYR A 1 105 ? 99.448  119.149 85.404  1.00 99.82  ? 49  TYR R CE2 1 
ATOM 123  C CZ  . TYR A 1 105 ? 98.975  120.058 86.325  1.00 99.82  ? 49  TYR R CZ  1 
ATOM 124  O OH  . TYR A 1 105 ? 97.894  119.730 87.112  1.00 99.82  ? 49  TYR R OH  1 
ATOM 125  N N   . PHE A 1 106 ? 105.239 120.081 85.157  1.00 91.36  ? 50  PHE R N   1 
ATOM 126  C CA  . PHE A 1 106 ? 105.907 119.096 86.005  1.00 91.36  ? 50  PHE R CA  1 
ATOM 127  C C   . PHE A 1 106 ? 106.732 119.777 87.095  1.00 91.36  ? 50  PHE R C   1 
ATOM 128  O O   . PHE A 1 106 ? 106.851 119.264 88.221  1.00 91.36  ? 50  PHE R O   1 
ATOM 129  C CB  . PHE A 1 106 ? 106.765 118.194 85.115  1.00 91.36  ? 50  PHE R CB  1 
ATOM 130  C CG  . PHE A 1 106 ? 107.985 117.634 85.781  1.00 91.36  ? 50  PHE R CG  1 
ATOM 131  C CD1 . PHE A 1 106 ? 107.890 116.559 86.647  1.00 91.36  ? 50  PHE R CD1 1 
ATOM 132  C CD2 . PHE A 1 106 ? 109.236 118.162 85.514  1.00 91.36  ? 50  PHE R CD2 1 
ATOM 133  C CE1 . PHE A 1 106 ? 109.018 116.033 87.246  1.00 91.36  ? 50  PHE R CE1 1 
ATOM 134  C CE2 . PHE A 1 106 ? 110.366 117.642 86.111  1.00 91.36  ? 50  PHE R CE2 1 
ATOM 135  C CZ  . PHE A 1 106 ? 110.258 116.576 86.977  1.00 91.36  ? 50  PHE R CZ  1 
ATOM 136  N N   . VAL A 1 107 ? 107.295 120.946 86.783  1.00 82.89  ? 51  VAL R N   1 
ATOM 137  C CA  . VAL A 1 107 ? 108.048 121.704 87.776  1.00 82.89  ? 51  VAL R CA  1 
ATOM 138  C C   . VAL A 1 107 ? 107.155 122.105 88.938  1.00 82.89  ? 51  VAL R C   1 
ATOM 139  O O   . VAL A 1 107 ? 107.617 122.201 90.080  1.00 82.89  ? 51  VAL R O   1 
ATOM 140  C CB  . VAL A 1 107 ? 108.700 122.933 87.117  1.00 82.89  ? 51  VAL R CB  1 
ATOM 141  C CG1 . VAL A 1 107 ? 109.161 123.913 88.170  1.00 82.89  ? 51  VAL R CG1 1 
ATOM 142  C CG2 . VAL A 1 107 ? 109.866 122.502 86.258  1.00 82.89  ? 51  VAL R CG2 1 
ATOM 143  N N   . VAL A 1 108 ? 105.871 122.348 88.679  1.00 79.02  ? 52  VAL R N   1 
ATOM 144  C CA  . VAL A 1 108 ? 104.975 122.723 89.767  1.00 79.02  ? 52  VAL R CA  1 
ATOM 145  C C   . VAL A 1 108 ? 104.879 121.600 90.786  1.00 79.02  ? 52  VAL R C   1 
ATOM 146  O O   . VAL A 1 108 ? 104.972 121.843 91.995  1.00 79.02  ? 52  VAL R O   1 
ATOM 147  C CB  . VAL A 1 108 ? 103.576 123.083 89.240  1.00 79.02  ? 52  VAL R CB  1 
ATOM 148  C CG1 . VAL A 1 108 ? 102.826 123.905 90.272  1.00 79.02  ? 52  VAL R CG1 1 
ATOM 149  C CG2 . VAL A 1 108 ? 103.655 123.825 87.926  1.00 79.02  ? 52  VAL R CG2 1 
ATOM 150  N N   . ILE A 1 109 ? 104.690 120.365 90.328  1.00 77.11  ? 53  ILE R N   1 
ATOM 151  C CA  . ILE A 1 109 ? 104.584 119.244 91.252  1.00 77.11  ? 53  ILE R CA  1 
ATOM 152  C C   . ILE A 1 109 ? 105.912 118.998 91.951  1.00 77.11  ? 53  ILE R C   1 
ATOM 153  O O   . ILE A 1 109 ? 105.943 118.676 93.143  1.00 77.11  ? 53  ILE R O   1 
ATOM 154  C CB  . ILE A 1 109 ? 104.084 117.990 90.514  1.00 77.11  ? 53  ILE R CB  1 
ATOM 155  C CG1 . ILE A 1 109 ? 102.675 118.224 89.964  1.00 77.11  ? 53  ILE R CG1 1 
ATOM 156  C CG2 . ILE A 1 109 ? 104.085 116.792 91.442  1.00 77.11  ? 53  ILE R CG2 1 
ATOM 157  C CD1 . ILE A 1 109 ? 102.440 117.597 88.612  1.00 77.11  ? 53  ILE R CD1 1 
ATOM 158  N N   . ILE A 1 110 ? 107.032 119.147 91.239  1.00 75.41  ? 54  ILE R N   1 
ATOM 159  C CA  . ILE A 1 110 ? 108.323 118.981 91.907  1.00 75.41  ? 54  ILE R CA  1 
ATOM 160  C C   . ILE A 1 110 ? 108.473 119.996 93.035  1.00 75.41  ? 54  ILE R C   1 
ATOM 161  O O   . ILE A 1 110 ? 108.874 119.651 94.157  1.00 75.41  ? 54  ILE R O   1 
ATOM 162  C CB  . ILE A 1 110 ? 109.478 119.095 90.896  1.00 75.41  ? 54  ILE R CB  1 
ATOM 163  C CG1 . ILE A 1 110 ? 109.461 117.916 89.924  1.00 75.41  ? 54  ILE R CG1 1 
ATOM 164  C CG2 . ILE A 1 110 ? 110.808 119.163 91.625  1.00 75.41  ? 54  ILE R CG2 1 
ATOM 165  C CD1 . ILE A 1 110 ? 109.792 116.575 90.561  1.00 75.41  ? 54  ILE R CD1 1 
ATOM 166  N N   . TYR A 1 111 ? 108.153 121.261 92.759  1.00 72.36  ? 55  TYR R N   1 
ATOM 167  C CA  . TYR A 1 111 ? 108.283 122.295 93.778  1.00 72.36  ? 55  TYR R CA  1 
ATOM 168  C C   . TYR A 1 111 ? 107.338 122.045 94.945  1.00 72.36  ? 55  TYR R C   1 
ATOM 169  O O   . TYR A 1 111 ? 107.711 122.249 96.102  1.00 72.36  ? 55  TYR R O   1 
ATOM 170  C CB  . TYR A 1 111 ? 108.021 123.669 93.169  1.00 72.36  ? 55  TYR R CB  1 
ATOM 171  C CG  . TYR A 1 111 ? 109.248 124.317 92.579  1.00 72.36  ? 55  TYR R CG  1 
ATOM 172  C CD1 . TYR A 1 111 ? 109.972 123.691 91.579  1.00 72.36  ? 55  TYR R CD1 1 
ATOM 173  C CD2 . TYR A 1 111 ? 109.680 125.556 93.021  1.00 72.36  ? 55  TYR R CD2 1 
ATOM 174  C CE1 . TYR A 1 111 ? 111.091 124.280 91.036  1.00 72.36  ? 55  TYR R CE1 1 
ATOM 175  C CE2 . TYR A 1 111 ? 110.798 126.151 92.483  1.00 72.36  ? 55  TYR R CE2 1 
ATOM 176  C CZ  . TYR A 1 111 ? 111.498 125.510 91.490  1.00 72.36  ? 55  TYR R CZ  1 
ATOM 177  O OH  . TYR A 1 111 ? 112.614 126.103 90.953  1.00 72.36  ? 55  TYR R OH  1 
ATOM 178  N N   . ALA A 1 112 ? 106.105 121.619 94.665  1.00 69.49  ? 56  ALA R N   1 
ATOM 179  C CA  . ALA A 1 112 ? 105.166 121.337 95.748  1.00 69.49  ? 56  ALA R CA  1 
ATOM 180  C C   . ALA A 1 112 ? 105.666 120.196 96.625  1.00 69.49  ? 56  ALA R C   1 
ATOM 181  O O   . ALA A 1 112 ? 105.577 120.259 97.858  1.00 69.49  ? 56  ALA R O   1 
ATOM 182  C CB  . ALA A 1 112 ? 103.790 121.005 95.174  1.00 69.49  ? 56  ALA R CB  1 
ATOM 183  N N   . LEU A 1 113 ? 106.186 119.139 96.006  1.00 69.49  ? 57  LEU R N   1 
ATOM 184  C CA  . LEU A 1 113 ? 106.702 118.020 96.780  1.00 69.49  ? 57  LEU R CA  1 
ATOM 185  C C   . LEU A 1 113 ? 107.858 118.460 97.666  1.00 69.49  ? 57  LEU R C   1 
ATOM 186  O O   . LEU A 1 113 ? 107.916 118.103 98.852  1.00 69.49  ? 57  LEU R O   1 
ATOM 187  C CB  . LEU A 1 113 ? 107.138 116.904 95.833  1.00 69.49  ? 57  LEU R CB  1 
ATOM 188  C CG  . LEU A 1 113 ? 107.684 115.633 96.473  1.00 69.49  ? 57  LEU R CG  1 
ATOM 189  C CD1 . LEU A 1 113 ? 106.577 114.900 97.214  1.00 69.49  ? 57  LEU R CD1 1 
ATOM 190  C CD2 . LEU A 1 113 ? 108.319 114.745 95.417  1.00 69.49  ? 57  LEU R CD2 1 
ATOM 191  N N   . VAL A 1 114 ? 108.786 119.240 97.110  1.00 69.49  ? 58  VAL R N   1 
ATOM 192  C CA  . VAL A 1 114 ? 109.917 119.702 97.906  1.00 69.49  ? 58  VAL R CA  1 
ATOM 193  C C   . VAL A 1 114 ? 109.437 120.618 99.023  1.00 69.49  ? 58  VAL R C   1 
ATOM 194  O O   . VAL A 1 114 ? 109.959 120.581 100.141 1.00 69.49  ? 58  VAL R O   1 
ATOM 195  C CB  . VAL A 1 114 ? 110.955 120.396 97.008  1.00 69.49  ? 58  VAL R CB  1 
ATOM 196  C CG1 . VAL A 1 114 ? 111.834 121.318 97.830  1.00 69.49  ? 58  VAL R CG1 1 
ATOM 197  C CG2 . VAL A 1 114 ? 111.791 119.365 96.282  1.00 69.49  ? 58  VAL R CG2 1 
ATOM 198  N N   . PHE A 1 115 ? 108.443 121.457 98.737  1.00 69.49  ? 59  PHE R N   1 
ATOM 199  C CA  . PHE A 1 115 ? 107.865 122.313 99.765  1.00 69.49  ? 59  PHE R CA  1 
ATOM 200  C C   . PHE A 1 115 ? 107.359 121.485 100.935 1.00 69.49  ? 59  PHE R C   1 
ATOM 201  O O   . PHE A 1 115 ? 107.705 121.746 102.092 1.00 69.49  ? 59  PHE R O   1 
ATOM 202  C CB  . PHE A 1 115 ? 106.732 123.136 99.156  1.00 69.49  ? 59  PHE R CB  1 
ATOM 203  C CG  . PHE A 1 115 ? 105.929 123.906 100.158 1.00 69.49  ? 59  PHE R CG  1 
ATOM 204  C CD1 . PHE A 1 115 ? 106.533 124.814 101.003 1.00 69.49  ? 59  PHE R CD1 1 
ATOM 205  C CD2 . PHE A 1 115 ? 104.563 123.718 100.252 1.00 69.49  ? 59  PHE R CD2 1 
ATOM 206  C CE1 . PHE A 1 115 ? 105.788 125.525 101.921 1.00 69.49  ? 59  PHE R CE1 1 
ATOM 207  C CE2 . PHE A 1 115 ? 103.815 124.424 101.168 1.00 69.49  ? 59  PHE R CE2 1 
ATOM 208  C CZ  . PHE A 1 115 ? 104.428 125.328 102.004 1.00 69.49  ? 59  PHE R CZ  1 
ATOM 209  N N   . LEU A 1 116 ? 106.542 120.470 100.650 1.00 69.49  ? 60  LEU R N   1 
ATOM 210  C CA  . LEU A 1 116 ? 105.980 119.656 101.725 1.00 69.49  ? 60  LEU R CA  1 
ATOM 211  C C   . LEU A 1 116 ? 107.078 118.958 102.516 1.00 69.49  ? 60  LEU R C   1 
ATOM 212  O O   . LEU A 1 116 ? 107.067 118.959 103.754 1.00 69.49  ? 60  LEU R O   1 
ATOM 213  C CB  . LEU A 1 116 ? 105.004 118.629 101.156 1.00 69.49  ? 60  LEU R CB  1 
ATOM 214  C CG  . LEU A 1 116 ? 103.766 119.187 100.458 1.00 69.49  ? 60  LEU R CG  1 
ATOM 215  C CD1 . LEU A 1 116 ? 102.975 118.054 99.827  1.00 69.49  ? 60  LEU R CD1 1 
ATOM 216  C CD2 . LEU A 1 116 ? 102.898 119.983 101.423 1.00 69.49  ? 60  LEU R CD2 1 
ATOM 217  N N   . LEU A 1 117 ? 108.037 118.346 101.817 1.00 69.49  ? 61  LEU R N   1 
ATOM 218  C CA  . LEU A 1 117 ? 109.072 117.592 102.519 1.00 69.49  ? 61  LEU R CA  1 
ATOM 219  C C   . LEU A 1 117 ? 109.934 118.504 103.384 1.00 69.49  ? 61  LEU R C   1 
ATOM 220  O O   . LEU A 1 117 ? 110.234 118.172 104.538 1.00 69.49  ? 61  LEU R O   1 
ATOM 221  C CB  . LEU A 1 117 ? 109.932 116.824 101.518 1.00 69.49  ? 61  LEU R CB  1 
ATOM 222  C CG  . LEU A 1 117 ? 109.208 115.733 100.727 1.00 69.49  ? 61  LEU R CG  1 
ATOM 223  C CD1 . LEU A 1 117 ? 110.137 115.126 99.691  1.00 69.49  ? 61  LEU R CD1 1 
ATOM 224  C CD2 . LEU A 1 117 ? 108.658 114.657 101.647 1.00 69.49  ? 61  LEU R CD2 1 
ATOM 225  N N   . SER A 1 118 ? 110.346 119.657 102.849 1.00 69.49  ? 62  SER R N   1 
ATOM 226  C CA  . SER A 1 118 ? 111.144 120.588 103.636 1.00 69.49  ? 62  SER R CA  1 
ATOM 227  C C   . SER A 1 118 ? 110.363 121.099 104.835 1.00 69.49  ? 62  SER R C   1 
ATOM 228  O O   . SER A 1 118 ? 110.899 121.170 105.946 1.00 69.49  ? 62  SER R O   1 
ATOM 229  C CB  . SER A 1 118 ? 111.599 121.755 102.764 1.00 69.49  ? 62  SER R CB  1 
ATOM 230  O OG  . SER A 1 118 ? 112.549 121.333 101.802 1.00 69.49  ? 62  SER R OG  1 
ATOM 231  N N   . LEU A 1 119 ? 109.094 121.452 104.632 1.00 69.49  ? 63  LEU R N   1 
ATOM 232  C CA  . LEU A 1 119 ? 108.269 121.908 105.742 1.00 69.49  ? 63  LEU R CA  1 
ATOM 233  C C   . LEU A 1 119 ? 108.246 120.870 106.854 1.00 69.49  ? 63  LEU R C   1 
ATOM 234  O O   . LEU A 1 119 ? 108.559 121.175 108.011 1.00 69.49  ? 63  LEU R O   1 
ATOM 235  C CB  . LEU A 1 119 ? 106.854 122.199 105.240 1.00 69.49  ? 63  LEU R CB  1 
ATOM 236  C CG  . LEU A 1 119 ? 105.796 122.606 106.264 1.00 69.49  ? 63  LEU R CG  1 
ATOM 237  C CD1 . LEU A 1 119 ? 106.141 123.942 106.897 1.00 69.49  ? 63  LEU R CD1 1 
ATOM 238  C CD2 . LEU A 1 119 ? 104.426 122.655 105.613 1.00 69.49  ? 63  LEU R CD2 1 
ATOM 239  N N   . LEU A 1 120 ? 107.910 119.625 106.514 1.00 69.49  ? 64  LEU R N   1 
ATOM 240  C CA  . LEU A 1 120 ? 107.783 118.600 107.545 1.00 69.49  ? 64  LEU R CA  1 
ATOM 241  C C   . LEU A 1 120 ? 109.112 118.349 108.245 1.00 69.49  ? 64  LEU R C   1 
ATOM 242  O O   . LEU A 1 120 ? 109.173 118.310 109.480 1.00 69.49  ? 64  LEU R O   1 
ATOM 243  C CB  . LEU A 1 120 ? 107.249 117.308 106.932 1.00 69.49  ? 64  LEU R CB  1 
ATOM 244  C CG  . LEU A 1 120 ? 107.046 116.134 107.891 1.00 69.49  ? 64  LEU R CG  1 
ATOM 245  C CD1 . LEU A 1 120 ? 105.884 116.408 108.824 1.00 69.49  ? 64  LEU R CD1 1 
ATOM 246  C CD2 . LEU A 1 120 ? 106.827 114.844 107.122 1.00 69.49  ? 64  LEU R CD2 1 
ATOM 247  N N   . GLY A 1 121 ? 110.190 118.182 107.478 1.00 69.49  ? 65  GLY R N   1 
ATOM 248  C CA  . GLY A 1 121 ? 111.466 117.853 108.092 1.00 69.49  ? 65  GLY R CA  1 
ATOM 249  C C   . GLY A 1 121 ? 111.984 118.958 108.991 1.00 69.49  ? 65  GLY R C   1 
ATOM 250  O O   . GLY A 1 121 ? 112.423 118.707 110.118 1.00 69.49  ? 65  GLY R O   1 
ATOM 251  N N   . ASN A 1 122 ? 111.944 120.199 108.508 1.00 69.49  ? 66  ASN R N   1 
ATOM 252  C CA  . ASN A 1 122 ? 112.449 121.305 109.307 1.00 69.49  ? 66  ASN R CA  1 
ATOM 253  C C   . ASN A 1 122 ? 111.579 121.535 110.533 1.00 69.49  ? 66  ASN R C   1 
ATOM 254  O O   . ASN A 1 122 ? 112.090 121.854 111.612 1.00 69.49  ? 66  ASN R O   1 
ATOM 255  C CB  . ASN A 1 122 ? 112.531 122.562 108.451 1.00 69.49  ? 66  ASN R CB  1 
ATOM 256  C CG  . ASN A 1 122 ? 113.490 122.407 107.293 1.00 69.49  ? 66  ASN R CG  1 
ATOM 257  O OD1 . ASN A 1 122 ? 114.389 121.573 107.326 1.00 69.49  ? 66  ASN R OD1 1 
ATOM 258  N ND2 . ASN A 1 122 ? 113.300 123.209 106.258 1.00 69.49  ? 66  ASN R ND2 1 
ATOM 259  N N   . SER A 1 123 ? 110.260 121.370 110.397 1.00 69.49  ? 67  SER R N   1 
ATOM 260  C CA  . SER A 1 123 ? 109.392 121.494 111.561 1.00 69.49  ? 67  SER R CA  1 
ATOM 261  C C   . SER A 1 123 ? 109.734 120.448 112.609 1.00 69.49  ? 67  SER R C   1 
ATOM 262  O O   . SER A 1 123 ? 109.778 120.754 113.805 1.00 69.49  ? 67  SER R O   1 
ATOM 263  C CB  . SER A 1 123 ? 107.930 121.367 111.141 1.00 69.49  ? 67  SER R CB  1 
ATOM 264  O OG  . SER A 1 123 ? 107.582 122.377 110.213 1.00 69.49  ? 67  SER R OG  1 
ATOM 265  N N   . LEU A 1 124 ? 109.977 119.205 112.187 1.00 69.49  ? 68  LEU R N   1 
ATOM 266  C CA  . LEU A 1 124 ? 110.333 118.173 113.156 1.00 69.49  ? 68  LEU R CA  1 
ATOM 267  C C   . LEU A 1 124 ? 111.668 118.474 113.823 1.00 69.49  ? 68  LEU R C   1 
ATOM 268  O O   . LEU A 1 124 ? 111.815 118.283 115.035 1.00 69.49  ? 68  LEU R O   1 
ATOM 269  C CB  . LEU A 1 124 ? 110.379 116.801 112.492 1.00 69.49  ? 68  LEU R CB  1 
ATOM 270  C CG  . LEU A 1 124 ? 109.040 116.154 112.146 1.00 69.49  ? 68  LEU R CG  1 
ATOM 271  C CD1 . LEU A 1 124 ? 109.290 114.771 111.570 1.00 69.49  ? 68  LEU R CD1 1 
ATOM 272  C CD2 . LEU A 1 124 ? 108.120 116.080 113.353 1.00 69.49  ? 68  LEU R CD2 1 
ATOM 273  N N   . VAL A 1 125 ? 112.657 118.929 113.055 1.00 69.49  ? 69  VAL R N   1 
ATOM 274  C CA  . VAL A 1 125 ? 113.954 119.250 113.649 1.00 69.49  ? 69  VAL R CA  1 
ATOM 275  C C   . VAL A 1 125 ? 113.795 120.355 114.685 1.00 69.49  ? 69  VAL R C   1 
ATOM 276  O O   . VAL A 1 125 ? 114.327 120.274 115.799 1.00 69.49  ? 69  VAL R O   1 
ATOM 277  C CB  . VAL A 1 125 ? 114.964 119.642 112.556 1.00 69.49  ? 69  VAL R CB  1 
ATOM 278  C CG1 . VAL A 1 125 ? 116.183 120.294 113.171 1.00 69.49  ? 69  VAL R CG1 1 
ATOM 279  C CG2 . VAL A 1 125 ? 115.365 118.430 111.746 1.00 69.49  ? 69  VAL R CG2 1 
ATOM 280  N N   . MET A 1 126 ? 113.046 121.401 114.333 1.00 69.49  ? 70  MET R N   1 
ATOM 281  C CA  . MET A 1 126 ? 112.819 122.496 115.267 1.00 69.49  ? 70  MET R CA  1 
ATOM 282  C C   . MET A 1 126 ? 112.103 122.014 116.519 1.00 69.49  ? 70  MET R C   1 
ATOM 283  O O   . MET A 1 126 ? 112.475 122.388 117.634 1.00 69.49  ? 70  MET R O   1 
ATOM 284  C CB  . MET A 1 126 ? 112.006 123.597 114.591 1.00 69.49  ? 70  MET R CB  1 
ATOM 285  C CG  . MET A 1 126 ? 112.821 124.786 114.146 1.00 69.49  ? 70  MET R CG  1 
ATOM 286  S SD  . MET A 1 126 ? 111.945 125.794 112.944 1.00 69.49  ? 70  MET R SD  1 
ATOM 287  C CE  . MET A 1 126 ? 113.046 127.199 112.840 1.00 69.49  ? 70  MET R CE  1 
ATOM 288  N N   . LEU A 1 127 ? 111.062 121.195 116.356 1.00 69.49  ? 71  LEU R N   1 
ATOM 289  C CA  . LEU A 1 127 ? 110.317 120.711 117.511 1.00 69.49  ? 71  LEU R CA  1 
ATOM 290  C C   . LEU A 1 127 ? 111.211 119.889 118.425 1.00 69.49  ? 71  LEU R C   1 
ATOM 291  O O   . LEU A 1 127 ? 111.202 120.067 119.646 1.00 69.49  ? 71  LEU R O   1 
ATOM 292  C CB  . LEU A 1 127 ? 109.116 119.886 117.049 1.00 69.49  ? 71  LEU R CB  1 
ATOM 293  C CG  . LEU A 1 127 ? 108.400 119.054 118.114 1.00 69.49  ? 71  LEU R CG  1 
ATOM 294  C CD1 . LEU A 1 127 ? 108.042 119.893 119.319 1.00 69.49  ? 71  LEU R CD1 1 
ATOM 295  C CD2 . LEU A 1 127 ? 107.156 118.414 117.536 1.00 69.49  ? 71  LEU R CD2 1 
ATOM 296  N N   . VAL A 1 128 ? 112.009 118.992 117.848 1.00 69.49  ? 72  VAL R N   1 
ATOM 297  C CA  . VAL A 1 128 ? 112.862 118.133 118.661 1.00 69.49  ? 72  VAL R CA  1 
ATOM 298  C C   . VAL A 1 128 ? 113.890 118.960 119.416 1.00 69.49  ? 72  VAL R C   1 
ATOM 299  O O   . VAL A 1 128 ? 114.160 118.710 120.596 1.00 69.49  ? 72  VAL R O   1 
ATOM 300  C CB  . VAL A 1 128 ? 113.530 117.063 117.783 1.00 69.49  ? 72  VAL R CB  1 
ATOM 301  C CG1 . VAL A 1 128 ? 114.659 116.399 118.537 1.00 69.49  ? 72  VAL R CG1 1 
ATOM 302  C CG2 . VAL A 1 128 ? 112.504 116.044 117.345 1.00 69.49  ? 72  VAL R CG2 1 
ATOM 303  N N   . ILE A 1 129 ? 114.494 119.945 118.753 1.00 69.49  ? 73  ILE R N   1 
ATOM 304  C CA  . ILE A 1 129 ? 115.521 120.735 119.423 1.00 69.49  ? 73  ILE R CA  1 
ATOM 305  C C   . ILE A 1 129 ? 114.913 121.639 120.488 1.00 69.49  ? 73  ILE R C   1 
ATOM 306  O O   . ILE A 1 129 ? 115.491 121.816 121.564 1.00 69.49  ? 73  ILE R O   1 
ATOM 307  C CB  . ILE A 1 129 ? 116.331 121.541 118.397 1.00 69.49  ? 73  ILE R CB  1 
ATOM 308  C CG1 . ILE A 1 129 ? 117.155 120.601 117.521 1.00 69.49  ? 73  ILE R CG1 1 
ATOM 309  C CG2 . ILE A 1 129 ? 117.232 122.527 119.111 1.00 69.49  ? 73  ILE R CG2 1 
ATOM 310  C CD1 . ILE A 1 129 ? 117.847 121.290 116.376 1.00 69.49  ? 73  ILE R CD1 1 
ATOM 311  N N   . LEU A 1 130 ? 113.753 122.232 120.218 1.00 69.49  ? 74  LEU R N   1 
ATOM 312  C CA  . LEU A 1 130 ? 113.173 123.238 121.096 1.00 69.49  ? 74  LEU R CA  1 
ATOM 313  C C   . LEU A 1 130 ? 112.278 122.654 122.176 1.00 69.49  ? 74  LEU R C   1 
ATOM 314  O O   . LEU A 1 130 ? 111.836 123.397 123.055 1.00 69.49  ? 74  LEU R O   1 
ATOM 315  C CB  . LEU A 1 130 ? 112.366 124.243 120.269 1.00 69.49  ? 74  LEU R CB  1 
ATOM 316  C CG  . LEU A 1 130 ? 113.159 125.204 119.381 1.00 69.49  ? 74  LEU R CG  1 
ATOM 317  C CD1 . LEU A 1 130 ? 112.218 126.107 118.615 1.00 69.49  ? 74  LEU R CD1 1 
ATOM 318  C CD2 . LEU A 1 130 ? 114.128 126.038 120.198 1.00 69.49  ? 74  LEU R CD2 1 
ATOM 319  N N   . TYR A 1 131 ? 111.985 121.357 122.134 1.00 69.49  ? 75  TYR R N   1 
ATOM 320  C CA  . TYR A 1 131 ? 111.087 120.782 123.128 1.00 69.49  ? 75  TYR R CA  1 
ATOM 321  C C   . TYR A 1 131 ? 111.742 120.718 124.501 1.00 69.49  ? 75  TYR R C   1 
ATOM 322  O O   . TYR A 1 131 ? 111.156 121.155 125.497 1.00 69.49  ? 75  TYR R O   1 
ATOM 323  C CB  . TYR A 1 131 ? 110.642 119.392 122.682 1.00 69.49  ? 75  TYR R CB  1 
ATOM 324  C CG  . TYR A 1 131 ? 109.434 118.863 123.412 1.00 69.49  ? 75  TYR R CG  1 
ATOM 325  C CD1 . TYR A 1 131 ? 109.555 118.267 124.656 1.00 69.49  ? 75  TYR R CD1 1 
ATOM 326  C CD2 . TYR A 1 131 ? 108.170 118.961 122.854 1.00 69.49  ? 75  TYR R CD2 1 
ATOM 327  C CE1 . TYR A 1 131 ? 108.453 117.775 125.320 1.00 69.49  ? 75  TYR R CE1 1 
ATOM 328  C CE2 . TYR A 1 131 ? 107.062 118.476 123.510 1.00 69.49  ? 75  TYR R CE2 1 
ATOM 329  C CZ  . TYR A 1 131 ? 107.208 117.885 124.742 1.00 69.49  ? 75  TYR R CZ  1 
ATOM 330  O OH  . TYR A 1 131 ? 106.101 117.401 125.400 1.00 69.49  ? 75  TYR R OH  1 
ATOM 331  N N   . SER A 1 132 ? 112.959 120.192 124.572 1.00 84.98  ? 76  SER R N   1 
ATOM 332  C CA  . SER A 1 132 ? 113.674 120.022 125.828 1.00 84.98  ? 76  SER R CA  1 
ATOM 333  C C   . SER A 1 132 ? 114.974 120.810 125.782 1.00 84.98  ? 76  SER R C   1 
ATOM 334  O O   . SER A 1 132 ? 115.765 120.654 124.846 1.00 84.98  ? 76  SER R O   1 
ATOM 335  C CB  . SER A 1 132 ? 113.954 118.542 126.095 1.00 84.98  ? 76  SER R CB  1 
ATOM 336  O OG  . SER A 1 132 ? 114.494 117.912 124.947 1.00 84.98  ? 76  SER R OG  1 
ATOM 337  N N   . ARG A 1 133 ? 115.194 121.646 126.794 1.00 89.75  ? 77  ARG R N   1 
ATOM 338  C CA  . ARG A 1 133 ? 116.390 122.473 126.876 1.00 89.75  ? 77  ARG R CA  1 
ATOM 339  C C   . ARG A 1 133 ? 117.597 121.713 127.403 1.00 89.75  ? 77  ARG R C   1 
ATOM 340  O O   . ARG A 1 133 ? 118.694 122.279 127.452 1.00 89.75  ? 77  ARG R O   1 
ATOM 341  C CB  . ARG A 1 133 ? 116.126 123.691 127.766 1.00 89.75  ? 77  ARG R CB  1 
ATOM 342  C CG  . ARG A 1 133 ? 115.275 124.756 127.102 1.00 89.75  ? 77  ARG R CG  1 
ATOM 343  C CD  . ARG A 1 133 ? 115.225 126.035 127.919 1.00 89.75  ? 77  ARG R CD  1 
ATOM 344  N NE  . ARG A 1 133 ? 114.707 127.152 127.137 1.00 89.75  ? 77  ARG R NE  1 
ATOM 345  C CZ  . ARG A 1 133 ? 114.461 128.360 127.624 1.00 89.75  ? 77  ARG R CZ  1 
ATOM 346  N NH1 . ARG A 1 133 ? 114.670 128.649 128.898 1.00 89.75  ? 77  ARG R NH1 1 
ATOM 347  N NH2 . ARG A 1 133 ? 113.990 129.303 126.812 1.00 89.75  ? 77  ARG R NH2 1 
ATOM 348  N N   . VAL A 1 134 ? 117.427 120.459 127.796 1.00 92.37  ? 78  VAL R N   1 
ATOM 349  C CA  . VAL A 1 134 ? 118.528 119.663 128.320 1.00 92.37  ? 78  VAL R CA  1 
ATOM 350  C C   . VAL A 1 134 ? 119.409 119.202 127.169 1.00 92.37  ? 78  VAL R C   1 
ATOM 351  O O   . VAL A 1 134 ? 118.915 118.767 126.122 1.00 92.37  ? 78  VAL R O   1 
ATOM 352  C CB  . VAL A 1 134 ? 117.990 118.468 129.124 1.00 92.37  ? 78  VAL R CB  1 
ATOM 353  C CG1 . VAL A 1 134 ? 119.138 117.688 129.751 1.00 92.37  ? 78  VAL R CG1 1 
ATOM 354  C CG2 . VAL A 1 134 ? 117.007 118.942 130.184 1.00 92.37  ? 78  VAL R CG2 1 
ATOM 355  N N   . GLY A 1 135 ? 120.722 119.292 127.362 1.00 79.88  ? 79  GLY R N   1 
ATOM 356  C CA  . GLY A 1 135 ? 121.658 118.855 126.340 1.00 79.88  ? 79  GLY R CA  1 
ATOM 357  C C   . GLY A 1 135 ? 121.651 119.701 125.088 1.00 79.88  ? 79  GLY R C   1 
ATOM 358  O O   . GLY A 1 135 ? 121.763 119.162 123.982 1.00 79.88  ? 79  GLY R O   1 
ATOM 359  N N   . ARG A 1 136 ? 121.527 121.018 125.229 1.00 73.27  ? 80  ARG R N   1 
ATOM 360  C CA  . ARG A 1 136 ? 121.584 121.931 124.090 1.00 73.27  ? 80  ARG R CA  1 
ATOM 361  C C   . ARG A 1 136 ? 123.045 122.282 123.847 1.00 73.27  ? 80  ARG R C   1 
ATOM 362  O O   . ARG A 1 136 ? 123.636 123.076 124.581 1.00 73.27  ? 80  ARG R O   1 
ATOM 363  C CB  . ARG A 1 136 ? 120.749 123.177 124.362 1.00 73.27  ? 80  ARG R CB  1 
ATOM 364  C CG  . ARG A 1 136 ? 119.277 122.886 124.607 1.00 73.27  ? 80  ARG R CG  1 
ATOM 365  C CD  . ARG A 1 136 ? 118.457 122.899 123.326 1.00 73.27  ? 80  ARG R CD  1 
ATOM 366  N NE  . ARG A 1 136 ? 118.250 124.253 122.827 1.00 73.27  ? 80  ARG R NE  1 
ATOM 367  C CZ  . ARG A 1 136 ? 117.147 124.965 123.019 1.00 73.27  ? 80  ARG R CZ  1 
ATOM 368  N NH1 . ARG A 1 136 ? 116.136 124.500 123.735 1.00 73.27  ? 80  ARG R NH1 1 
ATOM 369  N NH2 . ARG A 1 136 ? 117.059 126.180 122.487 1.00 73.27  ? 80  ARG R NH2 1 
ATOM 370  N N   . SER A 1 137 ? 123.634 121.688 122.815 1.00 69.49  ? 81  SER R N   1 
ATOM 371  C CA  . SER A 1 137 ? 125.045 121.858 122.517 1.00 69.49  ? 81  SER R CA  1 
ATOM 372  C C   . SER A 1 137 ? 125.232 122.861 121.382 1.00 69.49  ? 81  SER R C   1 
ATOM 373  O O   . SER A 1 137 ? 124.283 123.478 120.894 1.00 69.49  ? 81  SER R O   1 
ATOM 374  C CB  . SER A 1 137 ? 125.670 120.507 122.169 1.00 69.49  ? 81  SER R CB  1 
ATOM 375  O OG  . SER A 1 137 ? 124.756 119.701 121.452 1.00 69.49  ? 81  SER R OG  1 
ATOM 376  N N   . VAL A 1 138 ? 126.488 123.037 120.971 1.00 69.49  ? 82  VAL R N   1 
ATOM 377  C CA  . VAL A 1 138 ? 126.795 123.912 119.843 1.00 69.49  ? 82  VAL R CA  1 
ATOM 378  C C   . VAL A 1 138 ? 126.143 123.384 118.573 1.00 69.49  ? 82  VAL R C   1 
ATOM 379  O O   . VAL A 1 138 ? 125.580 124.148 117.774 1.00 69.49  ? 82  VAL R O   1 
ATOM 380  C CB  . VAL A 1 138 ? 128.320 124.050 119.683 1.00 69.49  ? 82  VAL R CB  1 
ATOM 381  C CG1 . VAL A 1 138 ? 128.913 124.726 120.903 1.00 69.49  ? 82  VAL R CG1 1 
ATOM 382  C CG2 . VAL A 1 138 ? 128.970 122.698 119.454 1.00 69.49  ? 82  VAL R CG2 1 
ATOM 383  N N   . THR A 1 139 ? 126.207 122.071 118.368 1.00 69.49  ? 83  THR R N   1 
ATOM 384  C CA  . THR A 1 139 ? 125.615 121.482 117.176 1.00 69.49  ? 83  THR R CA  1 
ATOM 385  C C   . THR A 1 139 ? 124.114 121.719 117.136 1.00 69.49  ? 83  THR R C   1 
ATOM 386  O O   . THR A 1 139 ? 123.547 121.950 116.066 1.00 69.49  ? 83  THR R O   1 
ATOM 387  C CB  . THR A 1 139 ? 125.923 119.990 117.126 1.00 69.49  ? 83  THR R CB  1 
ATOM 388  O OG1 . THR A 1 139 ? 127.332 119.792 117.290 1.00 69.49  ? 83  THR R OG1 1 
ATOM 389  C CG2 . THR A 1 139 ? 125.483 119.402 115.798 1.00 69.49  ? 83  THR R CG2 1 
ATOM 390  N N   . ASP A 1 140 ? 123.448 121.658 118.288 1.00 69.49  ? 84  ASP R N   1 
ATOM 391  C CA  . ASP A 1 140 ? 122.012 121.906 118.311 1.00 69.49  ? 84  ASP R CA  1 
ATOM 392  C C   . ASP A 1 140 ? 121.692 123.329 117.878 1.00 69.49  ? 84  ASP R C   1 
ATOM 393  O O   . ASP A 1 140 ? 120.728 123.555 117.143 1.00 69.49  ? 84  ASP R O   1 
ATOM 394  C CB  . ASP A 1 140 ? 121.452 121.630 119.703 1.00 69.49  ? 84  ASP R CB  1 
ATOM 395  C CG  . ASP A 1 140 ? 121.511 120.164 120.071 1.00 69.49  ? 84  ASP R CG  1 
ATOM 396  O OD1 . ASP A 1 140 ? 121.950 119.357 119.229 1.00 69.49  ? 84  ASP R OD1 1 
ATOM 397  O OD2 . ASP A 1 140 ? 121.117 119.818 121.202 1.00 69.49  ? 84  ASP R OD2 1 
ATOM 398  N N   . VAL A 1 141 ? 122.485 124.303 118.322 1.00 69.49  ? 85  VAL R N   1 
ATOM 399  C CA  . VAL A 1 141 ? 122.258 125.687 117.919 1.00 69.49  ? 85  VAL R CA  1 
ATOM 400  C C   . VAL A 1 141 ? 122.460 125.843 116.417 1.00 69.49  ? 85  VAL R C   1 
ATOM 401  O O   . VAL A 1 141 ? 121.650 126.477 115.722 1.00 69.49  ? 85  VAL R O   1 
ATOM 402  C CB  . VAL A 1 141 ? 123.180 126.627 118.712 1.00 69.49  ? 85  VAL R CB  1 
ATOM 403  C CG1 . VAL A 1 141 ? 123.132 128.023 118.138 1.00 69.49  ? 85  VAL R CG1 1 
ATOM 404  C CG2 . VAL A 1 141 ? 122.786 126.637 120.175 1.00 69.49  ? 85  VAL R CG2 1 
ATOM 405  N N   . TYR A 1 142 ? 123.544 125.268 115.891 1.00 69.49  ? 86  TYR R N   1 
ATOM 406  C CA  . TYR A 1 142 ? 123.777 125.344 114.453 1.00 69.49  ? 86  TYR R CA  1 
ATOM 407  C C   . TYR A 1 142 ? 122.627 124.714 113.680 1.00 69.49  ? 86  TYR R C   1 
ATOM 408  O O   . TYR A 1 142 ? 122.150 125.280 112.690 1.00 69.49  ? 86  TYR R O   1 
ATOM 409  C CB  . TYR A 1 142 ? 125.093 124.659 114.090 1.00 69.49  ? 86  TYR R CB  1 
ATOM 410  C CG  . TYR A 1 142 ? 126.325 125.485 114.366 1.00 69.49  ? 86  TYR R CG  1 
ATOM 411  C CD1 . TYR A 1 142 ? 126.472 126.750 113.824 1.00 69.49  ? 86  TYR R CD1 1 
ATOM 412  C CD2 . TYR A 1 142 ? 127.346 124.992 115.157 1.00 69.49  ? 86  TYR R CD2 1 
ATOM 413  C CE1 . TYR A 1 142 ? 127.593 127.502 114.075 1.00 69.49  ? 86  TYR R CE1 1 
ATOM 414  C CE2 . TYR A 1 142 ? 128.471 125.738 115.411 1.00 69.49  ? 86  TYR R CE2 1 
ATOM 415  C CZ  . TYR A 1 142 ? 128.589 126.991 114.866 1.00 69.49  ? 86  TYR R CZ  1 
ATOM 416  O OH  . TYR A 1 142 ? 129.713 127.737 115.117 1.00 69.49  ? 86  TYR R OH  1 
ATOM 417  N N   . LEU A 1 143 ? 122.166 123.543 114.121 1.00 69.49  ? 87  LEU R N   1 
ATOM 418  C CA  . LEU A 1 143 ? 121.081 122.863 113.425 1.00 69.49  ? 87  LEU R CA  1 
ATOM 419  C C   . LEU A 1 143 ? 119.792 123.661 113.502 1.00 69.49  ? 87  LEU R C   1 
ATOM 420  O O   . LEU A 1 143 ? 119.007 123.666 112.553 1.00 69.49  ? 87  LEU R O   1 
ATOM 421  C CB  . LEU A 1 143 ? 120.867 121.469 114.009 1.00 69.49  ? 87  LEU R CB  1 
ATOM 422  C CG  . LEU A 1 143 ? 122.000 120.463 113.837 1.00 69.49  ? 87  LEU R CG  1 
ATOM 423  C CD1 . LEU A 1 143 ? 121.649 119.170 114.546 1.00 69.49  ? 87  LEU R CD1 1 
ATOM 424  C CD2 . LEU A 1 143 ? 122.296 120.212 112.379 1.00 69.49  ? 87  LEU R CD2 1 
ATOM 425  N N   . LEU A 1 144 ? 119.537 124.319 114.630 1.00 69.49  ? 88  LEU R N   1 
ATOM 426  C CA  . LEU A 1 144 ? 118.327 125.122 114.747 1.00 69.49  ? 88  LEU R CA  1 
ATOM 427  C C   . LEU A 1 144 ? 118.352 126.291 113.771 1.00 69.49  ? 88  LEU R C   1 
ATOM 428  O O   . LEU A 1 144 ? 117.354 126.563 113.090 1.00 69.49  ? 88  LEU R O   1 
ATOM 429  C CB  . LEU A 1 144 ? 118.175 125.610 116.185 1.00 69.49  ? 88  LEU R CB  1 
ATOM 430  C CG  . LEU A 1 144 ? 116.805 126.145 116.586 1.00 69.49  ? 88  LEU R CG  1 
ATOM 431  C CD1 . LEU A 1 144 ? 115.808 125.018 116.704 1.00 69.49  ? 88  LEU R CD1 1 
ATOM 432  C CD2 . LEU A 1 144 ? 116.917 126.892 117.898 1.00 69.49  ? 88  LEU R CD2 1 
ATOM 433  N N   . ASN A 1 145 ? 119.489 126.982 113.670 1.00 69.49  ? 89  ASN R N   1 
ATOM 434  C CA  . ASN A 1 145 ? 119.589 128.055 112.684 1.00 69.49  ? 89  ASN R CA  1 
ATOM 435  C C   . ASN A 1 145 ? 119.428 127.518 111.267 1.00 69.49  ? 89  ASN R C   1 
ATOM 436  O O   . ASN A 1 145 ? 118.746 128.129 110.432 1.00 69.49  ? 89  ASN R O   1 
ATOM 437  C CB  . ASN A 1 145 ? 120.922 128.784 112.824 1.00 69.49  ? 89  ASN R CB  1 
ATOM 438  C CG  . ASN A 1 145 ? 120.977 129.660 114.045 1.00 69.49  ? 89  ASN R CG  1 
ATOM 439  O OD1 . ASN A 1 145 ? 120.108 130.501 114.255 1.00 69.49  ? 89  ASN R OD1 1 
ATOM 440  N ND2 . ASN A 1 145 ? 122.009 129.484 114.851 1.00 69.49  ? 89  ASN R ND2 1 
ATOM 441  N N   . LEU A 1 146 ? 120.056 126.379 110.974 1.00 69.49  ? 90  LEU R N   1 
ATOM 442  C CA  . LEU A 1 146 ? 119.968 125.809 109.635 1.00 69.49  ? 90  LEU R CA  1 
ATOM 443  C C   . LEU A 1 146 ? 118.537 125.415 109.298 1.00 69.49  ? 90  LEU R C   1 
ATOM 444  O O   . LEU A 1 146 ? 118.077 125.626 108.170 1.00 69.49  ? 90  LEU R O   1 
ATOM 445  C CB  . LEU A 1 146 ? 120.907 124.610 109.530 1.00 69.49  ? 90  LEU R CB  1 
ATOM 446  C CG  . LEU A 1 146 ? 121.154 124.021 108.147 1.00 69.49  ? 90  LEU R CG  1 
ATOM 447  C CD1 . LEU A 1 146 ? 121.844 125.024 107.252 1.00 69.49  ? 90  LEU R CD1 1 
ATOM 448  C CD2 . LEU A 1 146 ? 121.992 122.769 108.272 1.00 69.49  ? 90  LEU R CD2 1 
ATOM 449  N N   . ALA A 1 147 ? 117.821 124.837 110.262 1.00 69.49  ? 91  ALA R N   1 
ATOM 450  C CA  . ALA A 1 147 ? 116.425 124.483 110.046 1.00 69.49  ? 91  ALA R CA  1 
ATOM 451  C C   . ALA A 1 147 ? 115.579 125.722 109.805 1.00 69.49  ? 91  ALA R C   1 
ATOM 452  O O   . ALA A 1 147 ? 114.687 125.712 108.952 1.00 69.49  ? 91  ALA R O   1 
ATOM 453  C CB  . ALA A 1 147 ? 115.890 123.695 111.239 1.00 69.49  ? 91  ALA R CB  1 
ATOM 454  N N   . LEU A 1 148 ? 115.833 126.799 110.549 1.00 69.49  ? 92  LEU R N   1 
ATOM 455  C CA  . LEU A 1 148 ? 115.106 128.038 110.294 1.00 69.49  ? 92  LEU R CA  1 
ATOM 456  C C   . LEU A 1 148 ? 115.331 128.517 108.866 1.00 69.49  ? 92  LEU R C   1 
ATOM 457  O O   . LEU A 1 148 ? 114.377 128.876 108.160 1.00 69.49  ? 92  LEU R O   1 
ATOM 458  C CB  . LEU A 1 148 ? 115.539 129.112 111.289 1.00 69.49  ? 92  LEU R CB  1 
ATOM 459  C CG  . LEU A 1 148 ? 114.879 130.482 111.133 1.00 69.49  ? 92  LEU R CG  1 
ATOM 460  C CD1 . LEU A 1 148 ? 113.395 130.397 111.433 1.00 69.49  ? 92  LEU R CD1 1 
ATOM 461  C CD2 . LEU A 1 148 ? 115.553 131.500 112.033 1.00 69.49  ? 92  LEU R CD2 1 
ATOM 462  N N   . ALA A 1 149 ? 116.587 128.525 108.420 1.00 69.49  ? 93  ALA R N   1 
ATOM 463  C CA  . ALA A 1 149 ? 116.883 128.995 107.071 1.00 69.49  ? 93  ALA R CA  1 
ATOM 464  C C   . ALA A 1 149 ? 116.188 128.132 106.026 1.00 69.49  ? 93  ALA R C   1 
ATOM 465  O O   . ALA A 1 149 ? 115.563 128.647 105.088 1.00 69.49  ? 93  ALA R O   1 
ATOM 466  C CB  . ALA A 1 149 ? 118.393 129.004 106.842 1.00 69.49  ? 93  ALA R CB  1 
ATOM 467  N N   . ASP A 1 150 ? 116.283 126.811 106.175 1.00 69.49  ? 94  ASP R N   1 
ATOM 468  C CA  . ASP A 1 150 ? 115.673 125.912 105.203 1.00 69.49  ? 94  ASP R CA  1 
ATOM 469  C C   . ASP A 1 150 ? 114.157 126.052 105.196 1.00 69.49  ? 94  ASP R C   1 
ATOM 470  O O   . ASP A 1 150 ? 113.527 125.989 104.134 1.00 69.49  ? 94  ASP R O   1 
ATOM 471  C CB  . ASP A 1 150 ? 116.080 124.473 105.505 1.00 69.49  ? 94  ASP R CB  1 
ATOM 472  C CG  . ASP A 1 150 ? 117.575 124.262 105.416 1.00 69.49  ? 94  ASP R CG  1 
ATOM 473  O OD1 . ASP A 1 150 ? 118.283 125.205 105.011 1.00 69.49  ? 94  ASP R OD1 1 
ATOM 474  O OD2 . ASP A 1 150 ? 118.044 123.157 105.756 1.00 69.49  ? 94  ASP R OD2 1 
ATOM 475  N N   . LEU A 1 151 ? 113.551 126.232 106.370 1.00 69.49  ? 95  LEU R N   1 
ATOM 476  C CA  . LEU A 1 151 ? 112.106 126.398 106.435 1.00 69.49  ? 95  LEU R CA  1 
ATOM 477  C C   . LEU A 1 151 ? 111.669 127.674 105.733 1.00 69.49  ? 95  LEU R C   1 
ATOM 478  O O   . LEU A 1 151 ? 110.654 127.683 105.032 1.00 69.49  ? 95  LEU R O   1 
ATOM 479  C CB  . LEU A 1 151 ? 111.645 126.399 107.891 1.00 69.49  ? 95  LEU R CB  1 
ATOM 480  C CG  . LEU A 1 151 ? 110.152 126.626 108.119 1.00 69.49  ? 95  LEU R CG  1 
ATOM 481  C CD1 . LEU A 1 151 ? 109.324 125.584 107.396 1.00 69.49  ? 95  LEU R CD1 1 
ATOM 482  C CD2 . LEU A 1 151 ? 109.846 126.606 109.601 1.00 69.49  ? 95  LEU R CD2 1 
ATOM 483  N N   . LEU A 1 152 ? 112.418 128.765 105.905 1.00 69.49  ? 96  LEU R N   1 
ATOM 484  C CA  . LEU A 1 152 ? 112.063 129.998 105.204 1.00 69.49  ? 96  LEU R CA  1 
ATOM 485  C C   . LEU A 1 152 ? 112.204 129.840 103.691 1.00 69.49  ? 96  LEU R C   1 
ATOM 486  O O   . LEU A 1 152 ? 111.343 130.294 102.923 1.00 69.49  ? 96  LEU R O   1 
ATOM 487  C CB  . LEU A 1 152 ? 112.924 131.152 105.713 1.00 69.49  ? 96  LEU R CB  1 
ATOM 488  C CG  . LEU A 1 152 ? 112.723 131.552 107.177 1.00 69.49  ? 96  LEU R CG  1 
ATOM 489  C CD1 . LEU A 1 152 ? 113.614 132.725 107.533 1.00 69.49  ? 96  LEU R CD1 1 
ATOM 490  C CD2 . LEU A 1 152 ? 111.272 131.889 107.461 1.00 69.49  ? 96  LEU R CD2 1 
ATOM 491  N N   . PHE A 1 153 ? 113.281 129.192 103.244 1.00 69.49  ? 97  PHE R N   1 
ATOM 492  C CA  . PHE A 1 153 ? 113.462 128.948 101.815 1.00 69.49  ? 97  PHE R CA  1 
ATOM 493  C C   . PHE A 1 153 ? 112.297 128.137 101.250 1.00 69.49  ? 97  PHE R C   1 
ATOM 494  O O   . PHE A 1 153 ? 111.701 128.491 100.219 1.00 69.49  ? 97  PHE R O   1 
ATOM 495  C CB  . PHE A 1 153 ? 114.791 128.222 101.604 1.00 69.49  ? 97  PHE R CB  1 
ATOM 496  C CG  . PHE A 1 153 ? 115.220 128.118 100.173 1.00 69.49  ? 97  PHE R CG  1 
ATOM 497  C CD1 . PHE A 1 153 ? 114.804 127.061 99.387  1.00 69.49  ? 97  PHE R CD1 1 
ATOM 498  C CD2 . PHE A 1 153 ? 116.062 129.064 99.622  1.00 69.49  ? 97  PHE R CD2 1 
ATOM 499  C CE1 . PHE A 1 153 ? 115.209 126.958 98.074  1.00 69.49  ? 97  PHE R CE1 1 
ATOM 500  C CE2 . PHE A 1 153 ? 116.470 128.965 98.311  1.00 69.49  ? 97  PHE R CE2 1 
ATOM 501  C CZ  . PHE A 1 153 ? 116.043 127.911 97.536  1.00 69.49  ? 97  PHE R CZ  1 
ATOM 502  N N   . ALA A 1 154 ? 111.939 127.050 101.933 1.00 69.49  ? 98  ALA R N   1 
ATOM 503  C CA  . ALA A 1 154 ? 110.815 126.238 101.489 1.00 69.49  ? 98  ALA R CA  1 
ATOM 504  C C   . ALA A 1 154 ? 109.529 127.048 101.479 1.00 69.49  ? 98  ALA R C   1 
ATOM 505  O O   . ALA A 1 154 ? 108.712 126.918 100.562 1.00 69.49  ? 98  ALA R O   1 
ATOM 506  C CB  . ALA A 1 154 ? 110.671 125.014 102.388 1.00 69.49  ? 98  ALA R CB  1 
ATOM 507  N N   . LEU A 1 155 ? 109.327 127.888 102.492 1.00 69.49  ? 99  LEU R N   1 
ATOM 508  C CA  . LEU A 1 155 ? 108.123 128.701 102.555 1.00 69.49  ? 99  LEU R CA  1 
ATOM 509  C C   . LEU A 1 155 ? 108.033 129.669 101.387 1.00 69.49  ? 99  LEU R C   1 
ATOM 510  O O   . LEU A 1 155 ? 106.924 130.017 100.972 1.00 69.49  ? 99  LEU R O   1 
ATOM 511  C CB  . LEU A 1 155 ? 108.088 129.459 103.881 1.00 69.49  ? 99  LEU R CB  1 
ATOM 512  C CG  . LEU A 1 155 ? 106.879 130.354 104.137 1.00 69.49  ? 99  LEU R CG  1 
ATOM 513  C CD1 . LEU A 1 155 ? 105.670 129.504 104.487 1.00 69.49  ? 99  LEU R CD1 1 
ATOM 514  C CD2 . LEU A 1 155 ? 107.182 131.353 105.243 1.00 69.49  ? 99  LEU R CD2 1 
ATOM 515  N N   . THR A 1 156 ? 109.168 130.127 100.865 1.00 69.49  ? 100 THR R N   1 
ATOM 516  C CA  . THR A 1 156 ? 109.154 130.944 99.654  1.00 69.49  ? 100 THR R CA  1 
ATOM 517  C C   . THR A 1 156 ? 108.975 130.132 98.377  1.00 69.49  ? 100 THR R C   1 
ATOM 518  O O   . THR A 1 156 ? 108.573 130.699 97.357  1.00 69.49  ? 100 THR R O   1 
ATOM 519  C CB  . THR A 1 156 ? 110.445 131.758 99.527  1.00 69.49  ? 100 THR R CB  1 
ATOM 520  O OG1 . THR A 1 156 ? 111.578 130.910 99.745  1.00 69.49  ? 100 THR R OG1 1 
ATOM 521  C CG2 . THR A 1 156 ? 110.456 132.895 100.525 1.00 69.49  ? 100 THR R CG2 1 
ATOM 522  N N   . LEU A 1 157 ? 109.277 128.834 98.397  1.00 69.49  ? 101 LEU R N   1 
ATOM 523  C CA  . LEU A 1 157 ? 109.216 128.052 97.159  1.00 69.49  ? 101 LEU R CA  1 
ATOM 524  C C   . LEU A 1 157 ? 107.885 128.144 96.413  1.00 69.49  ? 101 LEU R C   1 
ATOM 525  O O   . LEU A 1 157 ? 107.907 128.298 95.179  1.00 69.49  ? 101 LEU R O   1 
ATOM 526  C CB  . LEU A 1 157 ? 109.547 126.587 97.459  1.00 69.49  ? 101 LEU R CB  1 
ATOM 527  C CG  . LEU A 1 157 ? 111.032 126.232 97.528  1.00 69.49  ? 101 LEU R CG  1 
ATOM 528  C CD1 . LEU A 1 157 ? 111.194 124.783 97.924  1.00 69.49  ? 101 LEU R CD1 1 
ATOM 529  C CD2 . LEU A 1 157 ? 111.736 126.508 96.210  1.00 69.49  ? 101 LEU R CD2 1 
ATOM 530  N N   . PRO A 1 158 ? 106.717 128.027 97.055  1.00 69.49  ? 102 PRO R N   1 
ATOM 531  C CA  . PRO A 1 158 ? 105.462 127.965 96.277  1.00 69.49  ? 102 PRO R CA  1 
ATOM 532  C C   . PRO A 1 158 ? 105.219 129.167 95.376  1.00 69.49  ? 102 PRO R C   1 
ATOM 533  O O   . PRO A 1 158 ? 104.687 129.012 94.267  1.00 69.49  ? 102 PRO R O   1 
ATOM 534  C CB  . PRO A 1 158 ? 104.382 127.857 97.362  1.00 69.49  ? 102 PRO R CB  1 
ATOM 535  C CG  . PRO A 1 158 ? 105.075 127.371 98.567  1.00 69.49  ? 102 PRO R CG  1 
ATOM 536  C CD  . PRO A 1 158 ? 106.477 127.880 98.498  1.00 69.49  ? 102 PRO R CD  1 
ATOM 537  N N   . ILE A 1 159 ? 105.577 130.370 95.827  1.00 69.49  ? 103 ILE R N   1 
ATOM 538  C CA  . ILE A 1 159 ? 105.424 131.546 94.979  1.00 69.49  ? 103 ILE R CA  1 
ATOM 539  C C   . ILE A 1 159 ? 106.308 131.418 93.748  1.00 69.49  ? 103 ILE R C   1 
ATOM 540  O O   . ILE A 1 159 ? 105.912 131.788 92.637  1.00 69.49  ? 103 ILE R O   1 
ATOM 541  C CB  . ILE A 1 159 ? 105.740 132.822 95.776  1.00 69.49  ? 103 ILE R CB  1 
ATOM 542  C CG1 . ILE A 1 159 ? 104.761 132.974 96.940  1.00 69.49  ? 103 ILE R CG1 1 
ATOM 543  C CG2 . ILE A 1 159 ? 105.667 134.038 94.874  1.00 69.49  ? 103 ILE R CG2 1 
ATOM 544  C CD1 . ILE A 1 159 ? 105.185 134.002 97.965  1.00 69.49  ? 103 ILE R CD1 1 
ATOM 545  N N   . TRP A 1 160 ? 107.516 130.885 93.925  1.00 69.49  ? 104 TRP R N   1 
ATOM 546  C CA  . TRP A 1 160 ? 108.394 130.640 92.788  1.00 69.49  ? 104 TRP R CA  1 
ATOM 547  C C   . TRP A 1 160 ? 107.774 129.633 91.828  1.00 69.49  ? 104 TRP R C   1 
ATOM 548  O O   . TRP A 1 160 ? 107.898 129.771 90.606  1.00 69.49  ? 104 TRP R O   1 
ATOM 549  C CB  . TRP A 1 160 ? 109.754 130.148 93.278  1.00 69.49  ? 104 TRP R CB  1 
ATOM 550  C CG  . TRP A 1 160 ? 110.900 130.827 92.613  1.00 69.49  ? 104 TRP R CG  1 
ATOM 551  C CD1 . TRP A 1 160 ? 111.758 130.287 91.701  1.00 69.49  ? 104 TRP R CD1 1 
ATOM 552  C CD2 . TRP A 1 160 ? 111.313 132.183 92.801  1.00 69.49  ? 104 TRP R CD2 1 
ATOM 553  N NE1 . TRP A 1 160 ? 112.683 131.225 91.311  1.00 69.49  ? 104 TRP R NE1 1 
ATOM 554  C CE2 . TRP A 1 160 ? 112.430 132.398 91.972  1.00 69.49  ? 104 TRP R CE2 1 
ATOM 555  C CE3 . TRP A 1 160 ? 110.848 133.236 93.591  1.00 69.49  ? 104 TRP R CE3 1 
ATOM 556  C CZ2 . TRP A 1 160 ? 113.087 133.622 91.912  1.00 69.49  ? 104 TRP R CZ2 1 
ATOM 557  C CZ3 . TRP A 1 160 ? 111.500 134.447 93.528  1.00 69.49  ? 104 TRP R CZ3 1 
ATOM 558  C CH2 . TRP A 1 160 ? 112.607 134.632 92.697  1.00 69.49  ? 104 TRP R CH2 1 
ATOM 559  N N   . ALA A 1 161 ? 107.110 128.606 92.361  1.00 69.49  ? 105 ALA R N   1 
ATOM 560  C CA  . ALA A 1 161 ? 106.450 127.633 91.496  1.00 69.49  ? 105 ALA R CA  1 
ATOM 561  C C   . ALA A 1 161 ? 105.345 128.287 90.674  1.00 69.49  ? 105 ALA R C   1 
ATOM 562  O O   . ALA A 1 161 ? 105.236 128.061 89.462  1.00 69.49  ? 105 ALA R O   1 
ATOM 563  C CB  . ALA A 1 161 ? 105.887 126.486 92.332  1.00 69.49  ? 105 ALA R CB  1 
ATOM 564  N N   . ALA A 1 162 ? 104.516 129.109 91.315  1.00 69.49  ? 106 ALA R N   1 
ATOM 565  C CA  . ALA A 1 162 ? 103.460 129.793 90.573  1.00 69.49  ? 106 ALA R CA  1 
ATOM 566  C C   . ALA A 1 162 ? 104.044 130.720 89.514  1.00 69.49  ? 106 ALA R C   1 
ATOM 567  O O   . ALA A 1 162 ? 103.518 130.807 88.393  1.00 69.49  ? 106 ALA R O   1 
ATOM 568  C CB  . ALA A 1 162 ? 102.566 130.573 91.532  1.00 69.49  ? 106 ALA R CB  1 
ATOM 569  N N   . SER A 1 163 ? 105.132 131.416 89.847  1.00 70.48  ? 107 SER R N   1 
ATOM 570  C CA  . SER A 1 163 ? 105.804 132.252 88.861  1.00 70.48  ? 107 SER R CA  1 
ATOM 571  C C   . SER A 1 163 ? 106.266 131.428 87.672  1.00 70.48  ? 107 SER R C   1 
ATOM 572  O O   . SER A 1 163 ? 106.046 131.811 86.518  1.00 70.48  ? 107 SER R O   1 
ATOM 573  C CB  . SER A 1 163 ? 106.992 132.955 89.507  1.00 70.48  ? 107 SER R CB  1 
ATOM 574  O OG  . SER A 1 163 ? 107.797 133.589 88.531  1.00 70.48  ? 107 SER R OG  1 
ATOM 575  N N   . LYS A 1 164 ? 106.905 130.287 87.932  1.00 76.37  ? 108 LYS R N   1 
ATOM 576  C CA  . LYS A 1 164 ? 107.319 129.416 86.840  1.00 76.37  ? 108 LYS R CA  1 
ATOM 577  C C   . LYS A 1 164 ? 106.125 128.991 86.003  1.00 76.37  ? 108 LYS R C   1 
ATOM 578  O O   . LYS A 1 164 ? 106.248 128.812 84.787  1.00 76.37  ? 108 LYS R O   1 
ATOM 579  C CB  . LYS A 1 164 ? 108.043 128.186 87.387  1.00 76.37  ? 108 LYS R CB  1 
ATOM 580  C CG  . LYS A 1 164 ? 109.348 128.500 88.097  1.00 76.37  ? 108 LYS R CG  1 
ATOM 581  C CD  . LYS A 1 164 ? 110.542 128.023 87.298  1.00 76.37  ? 108 LYS R CD  1 
ATOM 582  C CE  . LYS A 1 164 ? 111.843 128.493 87.914  1.00 76.37  ? 108 LYS R CE  1 
ATOM 583  N NZ  . LYS A 1 164 ? 113.021 127.896 87.230  1.00 76.37  ? 108 LYS R NZ  1 
ATOM 584  N N   . VAL A 1 165 ? 104.963 128.825 86.632  1.00 75.00  ? 109 VAL R N   1 
ATOM 585  C CA  . VAL A 1 165 ? 103.769 128.452 85.880  1.00 75.00  ? 109 VAL R CA  1 
ATOM 586  C C   . VAL A 1 165 ? 103.388 129.559 84.907  1.00 75.00  ? 109 VAL R C   1 
ATOM 587  O O   . VAL A 1 165 ? 103.244 129.323 83.702  1.00 75.00  ? 109 VAL R O   1 
ATOM 588  C CB  . VAL A 1 165 ? 102.604 128.128 86.831  1.00 75.00  ? 109 VAL R CB  1 
ATOM 589  C CG1 . VAL A 1 165 ? 101.275 128.190 86.087  1.00 75.00  ? 109 VAL R CG1 1 
ATOM 590  C CG2 . VAL A 1 165 ? 102.797 126.770 87.446  1.00 75.00  ? 109 VAL R CG2 1 
ATOM 591  N N   . ASN A 1 166 ? 103.225 130.785 85.410  1.00 73.39  ? 110 ASN R N   1 
ATOM 592  C CA  . ASN A 1 166 ? 102.658 131.854 84.594  1.00 73.39  ? 110 ASN R CA  1 
ATOM 593  C C   . ASN A 1 166 ? 103.454 133.152 84.595  1.00 73.39  ? 110 ASN R C   1 
ATOM 594  O O   . ASN A 1 166 ? 102.905 134.191 84.214  1.00 73.39  ? 110 ASN R O   1 
ATOM 595  C CB  . ASN A 1 166 ? 101.222 132.151 85.044  1.00 73.39  ? 110 ASN R CB  1 
ATOM 596  C CG  . ASN A 1 166 ? 100.364 132.688 83.920  1.00 73.39  ? 110 ASN R CG  1 
ATOM 597  O OD1 . ASN A 1 166 ? 100.455 132.230 82.783  1.00 73.39  ? 110 ASN R OD1 1 
ATOM 598  N ND2 . ASN A 1 166 ? 99.519  133.661 84.234  1.00 73.39  ? 110 ASN R ND2 1 
ATOM 599  N N   . GLY A 1 167 ? 104.717 133.134 84.996  1.00 72.16  ? 111 GLY R N   1 
ATOM 600  C CA  . GLY A 1 167 ? 105.515 134.343 85.037  1.00 72.16  ? 111 GLY R CA  1 
ATOM 601  C C   . GLY A 1 167 ? 105.133 135.214 86.214  1.00 72.16  ? 111 GLY R C   1 
ATOM 602  O O   . GLY A 1 167 ? 104.106 135.023 86.870  1.00 72.16  ? 111 GLY R O   1 
ATOM 603  N N   . TRP A 1 168 ? 105.973 136.208 86.477  1.00 60.79  ? 112 TRP R N   1 
ATOM 604  C CA  . TRP A 1 168 ? 105.785 137.046 87.658  1.00 60.79  ? 112 TRP R CA  1 
ATOM 605  C C   . TRP A 1 168 ? 104.651 138.027 87.400  1.00 60.79  ? 112 TRP R C   1 
ATOM 606  O O   . TRP A 1 168 ? 104.850 139.126 86.886  1.00 60.79  ? 112 TRP R O   1 
ATOM 607  C CB  . TRP A 1 168 ? 107.068 137.775 88.027  1.00 60.79  ? 112 TRP R CB  1 
ATOM 608  C CG  . TRP A 1 168 ? 107.054 138.172 89.448  1.00 60.79  ? 112 TRP R CG  1 
ATOM 609  C CD1 . TRP A 1 168 ? 106.751 139.394 89.950  1.00 60.79  ? 112 TRP R CD1 1 
ATOM 610  C CD2 . TRP A 1 168 ? 107.320 137.329 90.571  1.00 60.79  ? 112 TRP R CD2 1 
ATOM 611  N NE1 . TRP A 1 168 ? 106.819 139.371 91.319  1.00 60.79  ? 112 TRP R NE1 1 
ATOM 612  C CE2 . TRP A 1 168 ? 107.169 138.111 91.723  1.00 60.79  ? 112 TRP R CE2 1 
ATOM 613  C CE3 . TRP A 1 168 ? 107.678 135.989 90.711  1.00 60.79  ? 112 TRP R CE3 1 
ATOM 614  C CZ2 . TRP A 1 168 ? 107.364 137.599 93.000  1.00 60.79  ? 112 TRP R CZ2 1 
ATOM 615  C CZ3 . TRP A 1 168 ? 107.871 135.484 91.976  1.00 60.79  ? 112 TRP R CZ3 1 
ATOM 616  C CH2 . TRP A 1 168 ? 107.715 136.285 93.103  1.00 60.79  ? 112 TRP R CH2 1 
ATOM 617  N N   . ILE A 1 169 ? 103.440 137.623 87.780  1.00 69.49  ? 113 ILE R N   1 
ATOM 618  C CA  . ILE A 1 169 ? 102.266 138.480 87.692  1.00 69.49  ? 113 ILE R CA  1 
ATOM 619  C C   . ILE A 1 169 ? 101.917 139.098 89.042  1.00 69.49  ? 113 ILE R C   1 
ATOM 620  O O   . ILE A 1 169 ? 100.844 139.687 89.191  1.00 69.49  ? 113 ILE R O   1 
ATOM 621  C CB  . ILE A 1 169 ? 101.067 137.701 87.128  1.00 69.49  ? 113 ILE R CB  1 
ATOM 622  C CG1 . ILE A 1 169 ? 101.476 136.918 85.879  1.00 69.49  ? 113 ILE R CG1 1 
ATOM 623  C CG2 . ILE A 1 169 ? 99.917  138.643 86.796  1.00 69.49  ? 113 ILE R CG2 1 
ATOM 624  C CD1 . ILE A 1 169 ? 102.115 137.770 84.803  1.00 69.49  ? 113 ILE R CD1 1 
ATOM 625  N N   . PHE A 1 170 ? 102.803 138.985 90.029  1.00 69.49  ? 114 PHE R N   1 
ATOM 626  C CA  . PHE A 1 170 ? 102.473 139.348 91.399  1.00 69.49  ? 114 PHE R CA  1 
ATOM 627  C C   . PHE A 1 170 ? 102.896 140.760 91.778  1.00 69.49  ? 114 PHE R C   1 
ATOM 628  O O   . PHE A 1 170 ? 102.590 141.199 92.891  1.00 69.49  ? 114 PHE R O   1 
ATOM 629  C CB  . PHE A 1 170 ? 103.112 138.346 92.361  1.00 69.49  ? 114 PHE R CB  1 
ATOM 630  C CG  . PHE A 1 170 ? 102.710 136.929 92.096  1.00 69.49  ? 114 PHE R CG  1 
ATOM 631  C CD1 . PHE A 1 170 ? 101.444 136.483 92.425  1.00 69.49  ? 114 PHE R CD1 1 
ATOM 632  C CD2 . PHE A 1 170 ? 103.591 136.046 91.506  1.00 69.49  ? 114 PHE R CD2 1 
ATOM 633  C CE1 . PHE A 1 170 ? 101.069 135.182 92.176  1.00 69.49  ? 114 PHE R CE1 1 
ATOM 634  C CE2 . PHE A 1 170 ? 103.221 134.747 91.255  1.00 69.49  ? 114 PHE R CE2 1 
ATOM 635  C CZ  . PHE A 1 170 ? 101.959 134.314 91.591  1.00 69.49  ? 114 PHE R CZ  1 
ATOM 636  N N   . GLY A 1 171 ? 103.576 141.480 90.898  1.00 69.49  ? 115 GLY R N   1 
ATOM 637  C CA  . GLY A 1 171 ? 103.967 142.850 91.153  1.00 69.49  ? 115 GLY R CA  1 
ATOM 638  C C   . GLY A 1 171 ? 105.418 142.961 91.591  1.00 69.49  ? 115 GLY R C   1 
ATOM 639  O O   . GLY A 1 171 ? 106.107 141.974 91.850  1.00 69.49  ? 115 GLY R O   1 
ATOM 640  N N   . THR A 1 172 ? 105.875 144.213 91.669  1.00 69.49  ? 116 THR R N   1 
ATOM 641  C CA  . THR A 1 172 ? 107.266 144.484 92.010  1.00 69.49  ? 116 THR R CA  1 
ATOM 642  C C   . THR A 1 172 ? 107.545 144.297 93.493  1.00 69.49  ? 116 THR R C   1 
ATOM 643  O O   . THR A 1 172 ? 108.628 143.826 93.862  1.00 69.49  ? 116 THR R O   1 
ATOM 644  C CB  . THR A 1 172 ? 107.642 145.907 91.599  1.00 69.49  ? 116 THR R CB  1 
ATOM 645  O OG1 . THR A 1 172 ? 107.621 146.021 90.172  1.00 69.49  ? 116 THR R OG1 1 
ATOM 646  C CG2 . THR A 1 172 ? 109.024 146.260 92.111  1.00 69.49  ? 116 THR R CG2 1 
ATOM 647  N N   . PHE A 1 173 ? 106.597 144.670 94.355  1.00 69.49  ? 117 PHE R N   1 
ATOM 648  C CA  . PHE A 1 173 ? 106.826 144.569 95.791  1.00 69.49  ? 117 PHE R CA  1 
ATOM 649  C C   . PHE A 1 173 ? 107.119 143.132 96.193  1.00 69.49  ? 117 PHE R C   1 
ATOM 650  O O   . PHE A 1 173 ? 108.095 142.857 96.902  1.00 69.49  ? 117 PHE R O   1 
ATOM 651  C CB  . PHE A 1 173 ? 105.615 145.104 96.551  1.00 69.49  ? 117 PHE R CB  1 
ATOM 652  C CG  . PHE A 1 173 ? 105.789 145.104 98.038  1.00 69.49  ? 117 PHE R CG  1 
ATOM 653  C CD1 . PHE A 1 173 ? 106.711 145.940 98.639  1.00 69.49  ? 117 PHE R CD1 1 
ATOM 654  C CD2 . PHE A 1 173 ? 105.030 144.272 98.836  1.00 69.49  ? 117 PHE R CD2 1 
ATOM 655  C CE1 . PHE A 1 173 ? 106.875 145.940 100.005 1.00 69.49  ? 117 PHE R CE1 1 
ATOM 656  C CE2 . PHE A 1 173 ? 105.190 144.269 100.202 1.00 69.49  ? 117 PHE R CE2 1 
ATOM 657  C CZ  . PHE A 1 173 ? 106.114 145.104 100.788 1.00 69.49  ? 117 PHE R CZ  1 
ATOM 658  N N   . LEU A 1 174 ? 106.287 142.196 95.739  1.00 69.49  ? 118 LEU R N   1 
ATOM 659  C CA  . LEU A 1 174 ? 106.513 140.800 96.079  1.00 69.49  ? 118 LEU R CA  1 
ATOM 660  C C   . LEU A 1 174 ? 107.759 140.255 95.398  1.00 69.49  ? 118 LEU R C   1 
ATOM 661  O O   . LEU A 1 174 ? 108.453 139.417 95.976  1.00 69.49  ? 118 LEU R O   1 
ATOM 662  C CB  . LEU A 1 174 ? 105.288 139.966 95.719  1.00 69.49  ? 118 LEU R CB  1 
ATOM 663  C CG  . LEU A 1 174 ? 104.031 140.339 96.506  1.00 69.49  ? 118 LEU R CG  1 
ATOM 664  C CD1 . LEU A 1 174 ? 102.826 139.581 95.984  1.00 69.49  ? 118 LEU R CD1 1 
ATOM 665  C CD2 . LEU A 1 174 ? 104.232 140.073 97.985  1.00 69.49  ? 118 LEU R CD2 1 
ATOM 666  N N   . CYS A 1 175 ? 108.074 140.721 94.190  1.00 69.49  ? 119 CYS R N   1 
ATOM 667  C CA  . CYS A 1 175 ? 109.337 140.332 93.572  1.00 69.49  ? 119 CYS R CA  1 
ATOM 668  C C   . CYS A 1 175 ? 110.503 140.662 94.492  1.00 69.49  ? 119 CYS R C   1 
ATOM 669  O O   . CYS A 1 175 ? 111.302 139.784 94.841  1.00 69.49  ? 119 CYS R O   1 
ATOM 670  C CB  . CYS A 1 175 ? 109.491 141.024 92.215  1.00 59.58  ? 119 CYS R CB  1 
ATOM 671  S SG  . CYS A 1 175 ? 111.166 141.088 91.534  1.00 59.58  ? 119 CYS R SG  1 
ATOM 672  N N   . LYS A 1 176 ? 110.581 141.914 94.947  1.00 69.49  ? 120 LYS R N   1 
ATOM 673  C CA  . LYS A 1 176 ? 111.678 142.315 95.823  1.00 69.49  ? 120 LYS R CA  1 
ATOM 674  C C   . LYS A 1 176 ? 111.668 141.523 97.126  1.00 69.49  ? 120 LYS R C   1 
ATOM 675  O O   . LYS A 1 176 ? 112.705 141.008 97.559  1.00 69.49  ? 120 LYS R O   1 
ATOM 676  C CB  . LYS A 1 176 ? 111.598 143.813 96.113  1.00 54.08  ? 120 LYS R CB  1 
ATOM 677  C CG  . LYS A 1 176 ? 111.920 144.699 94.930  1.00 54.08  ? 120 LYS R CG  1 
ATOM 678  C CD  . LYS A 1 176 ? 111.909 146.158 95.332  1.00 54.08  ? 120 LYS R CD  1 
ATOM 679  C CE  . LYS A 1 176 ? 112.326 147.057 94.188  1.00 54.08  ? 120 LYS R CE  1 
ATOM 680  N NZ  . LYS A 1 176 ? 113.785 146.993 93.945  1.00 54.08  ? 120 LYS R NZ  1 
ATOM 681  N N   . VAL A 1 177 ? 110.502 141.408 97.766  1.00 69.49  ? 121 VAL R N   1 
ATOM 682  C CA  . VAL A 1 177 ? 110.444 140.783 99.086  1.00 69.49  ? 121 VAL R CA  1 
ATOM 683  C C   . VAL A 1 177 ? 110.826 139.309 99.001  1.00 69.49  ? 121 VAL R C   1 
ATOM 684  O O   . VAL A 1 177 ? 111.667 138.821 99.768  1.00 69.49  ? 121 VAL R O   1 
ATOM 685  C CB  . VAL A 1 177 ? 109.045 140.964 99.700  1.00 69.49  ? 121 VAL R CB  1 
ATOM 686  C CG1 . VAL A 1 177 ? 108.922 140.167 100.985 1.00 69.49  ? 121 VAL R CG1 1 
ATOM 687  C CG2 . VAL A 1 177 ? 108.768 142.428 99.959  1.00 69.49  ? 121 VAL R CG2 1 
ATOM 688  N N   . VAL A 1 178 ? 110.210 138.575 98.074  1.00 69.49  ? 122 VAL R N   1 
ATOM 689  C CA  . VAL A 1 178 ? 110.475 137.150 97.960  1.00 69.49  ? 122 VAL R CA  1 
ATOM 690  C C   . VAL A 1 178 ? 111.914 136.909 97.533  1.00 69.49  ? 122 VAL R C   1 
ATOM 691  O O   . VAL A 1 178 ? 112.565 135.975 98.015  1.00 69.49  ? 122 VAL R O   1 
ATOM 692  C CB  . VAL A 1 178 ? 109.477 136.504 96.986  1.00 69.49  ? 122 VAL R CB  1 
ATOM 693  C CG1 . VAL A 1 178 ? 109.787 135.031 96.808  1.00 69.49  ? 122 VAL R CG1 1 
ATOM 694  C CG2 . VAL A 1 178 ? 108.057 136.694 97.485  1.00 69.49  ? 122 VAL R CG2 1 
ATOM 695  N N   . SER A 1 179 ? 112.438 137.731 96.621  1.00 69.49  ? 123 SER R N   1 
ATOM 696  C CA  . SER A 1 179 ? 113.823 137.558 96.207  1.00 69.49  ? 123 SER R CA  1 
ATOM 697  C C   . SER A 1 179 ? 114.770 137.771 97.378  1.00 69.49  ? 123 SER R C   1 
ATOM 698  O O   . SER A 1 179 ? 115.721 137.001 97.568  1.00 69.49  ? 123 SER R O   1 
ATOM 699  C CB  . SER A 1 179 ? 114.141 138.521 95.068  1.00 69.49  ? 123 SER R CB  1 
ATOM 700  O OG  . SER A 1 179 ? 113.268 138.314 93.974  1.00 69.49  ? 123 SER R OG  1 
ATOM 701  N N   . LEU A 1 180 ? 114.518 138.805 98.185  1.00 69.49  ? 124 LEU R N   1 
ATOM 702  C CA  . LEU A 1 180 ? 115.360 139.052 99.348  1.00 69.49  ? 124 LEU R CA  1 
ATOM 703  C C   . LEU A 1 180 ? 115.320 137.872 100.307 1.00 69.49  ? 124 LEU R C   1 
ATOM 704  O O   . LEU A 1 180 ? 116.362 137.404 100.774 1.00 69.49  ? 124 LEU R O   1 
ATOM 705  C CB  . LEU A 1 180 ? 114.916 140.331 100.058 1.00 69.49  ? 124 LEU R CB  1 
ATOM 706  C CG  . LEU A 1 180 ? 115.690 140.696 101.327 1.00 69.49  ? 124 LEU R CG  1 
ATOM 707  C CD1 . LEU A 1 180 ? 117.157 140.917 101.016 1.00 69.49  ? 124 LEU R CD1 1 
ATOM 708  C CD2 . LEU A 1 180 ? 115.095 141.923 101.991 1.00 69.49  ? 124 LEU R CD2 1 
ATOM 709  N N   . LEU A 1 181 ? 114.122 137.374 100.613 1.00 69.49  ? 125 LEU R N   1 
ATOM 710  C CA  . LEU A 1 181 ? 114.019 136.258 101.548 1.00 69.49  ? 125 LEU R CA  1 
ATOM 711  C C   . LEU A 1 181 ? 114.752 135.033 101.015 1.00 69.49  ? 125 LEU R C   1 
ATOM 712  O O   . LEU A 1 181 ? 115.544 134.401 101.729 1.00 69.49  ? 125 LEU R O   1 
ATOM 713  C CB  . LEU A 1 181 ? 112.551 135.934 101.817 1.00 69.49  ? 125 LEU R CB  1 
ATOM 714  C CG  . LEU A 1 181 ? 112.237 135.466 103.238 1.00 69.49  ? 125 LEU R CG  1 
ATOM 715  C CD1 . LEU A 1 181 ? 112.236 136.643 104.194 1.00 69.49  ? 125 LEU R CD1 1 
ATOM 716  C CD2 . LEU A 1 181 ? 110.908 134.740 103.289 1.00 69.49  ? 125 LEU R CD2 1 
ATOM 717  N N   . LYS A 1 182 ? 114.519 134.699 99.745  1.00 69.49  ? 126 LYS R N   1 
ATOM 718  C CA  . LYS A 1 182 ? 115.146 133.523 99.156  1.00 69.49  ? 126 LYS R CA  1 
ATOM 719  C C   . LYS A 1 182 ? 116.664 133.621 99.213  1.00 69.49  ? 126 LYS R C   1 
ATOM 720  O O   . LYS A 1 182 ? 117.340 132.682 99.647  1.00 69.49  ? 126 LYS R O   1 
ATOM 721  C CB  . LYS A 1 182 ? 114.671 133.354 97.713  1.00 69.49  ? 126 LYS R CB  1 
ATOM 722  C CG  . LYS A 1 182 ? 115.203 132.113 97.027  1.00 69.49  ? 126 LYS R CG  1 
ATOM 723  C CD  . LYS A 1 182 ? 114.586 131.923 95.654  1.00 69.49  ? 126 LYS R CD  1 
ATOM 724  C CE  . LYS A 1 182 ? 115.106 130.660 94.989  1.00 69.49  ? 126 LYS R CE  1 
ATOM 725  N NZ  . LYS A 1 182 ? 114.353 130.316 93.752  1.00 69.49  ? 126 LYS R NZ  1 
ATOM 726  N N   . GLU A 1 183 ? 117.226 134.756 98.783  1.00 69.49  ? 127 GLU R N   1 
ATOM 727  C CA  . GLU A 1 183 ? 118.680 134.850 98.725  1.00 69.49  ? 127 GLU R CA  1 
ATOM 728  C C   . GLU A 1 183 ? 119.298 134.941 100.113 1.00 69.49  ? 127 GLU R C   1 
ATOM 729  O O   . GLU A 1 183 ? 120.373 134.370 100.352 1.00 69.49  ? 127 GLU R O   1 
ATOM 730  C CB  . GLU A 1 183 ? 119.107 136.045 97.881  1.00 69.49  ? 127 GLU R CB  1 
ATOM 731  C CG  . GLU A 1 183 ? 120.435 135.813 97.183  1.00 69.49  ? 127 GLU R CG  1 
ATOM 732  C CD  . GLU A 1 183 ? 121.005 137.067 96.564  1.00 69.49  ? 127 GLU R CD  1 
ATOM 733  O OE1 . GLU A 1 183 ? 120.539 138.169 96.917  1.00 69.49  ? 127 GLU R OE1 1 
ATOM 734  O OE2 . GLU A 1 183 ? 121.923 136.949 95.724  1.00 69.49  ? 127 GLU R OE2 1 
ATOM 735  N N   . VAL A 1 184 ? 118.648 135.644 101.041 1.00 69.49  ? 128 VAL R N   1 
ATOM 736  C CA  . VAL A 1 184 ? 119.145 135.690 102.410 1.00 69.49  ? 128 VAL R CA  1 
ATOM 737  C C   . VAL A 1 184 ? 119.251 134.282 102.967 1.00 69.49  ? 128 VAL R C   1 
ATOM 738  O O   . VAL A 1 184 ? 120.278 133.894 103.534 1.00 69.49  ? 128 VAL R O   1 
ATOM 739  C CB  . VAL A 1 184 ? 118.232 136.572 103.280 1.00 69.49  ? 128 VAL R CB  1 
ATOM 740  C CG1 . VAL A 1 184 ? 118.450 136.282 104.753 1.00 69.49  ? 128 VAL R CG1 1 
ATOM 741  C CG2 . VAL A 1 184 ? 118.479 138.038 102.985 1.00 69.49  ? 128 VAL R CG2 1 
ATOM 742  N N   . ASN A 1 185 ? 118.197 133.484 102.792 1.00 69.49  ? 129 ASN R N   1 
ATOM 743  C CA  . ASN A 1 185 ? 118.212 132.144 103.360 1.00 69.49  ? 129 ASN R CA  1 
ATOM 744  C C   . ASN A 1 185 ? 119.181 131.225 102.624 1.00 69.49  ? 129 ASN R C   1 
ATOM 745  O O   . ASN A 1 185 ? 119.773 130.337 103.241 1.00 69.49  ? 129 ASN R O   1 
ATOM 746  C CB  . ASN A 1 185 ? 116.800 131.576 103.360 1.00 69.49  ? 129 ASN R CB  1 
ATOM 747  C CG  . ASN A 1 185 ? 115.894 132.299 104.330 1.00 69.49  ? 129 ASN R CG  1 
ATOM 748  O OD1 . ASN A 1 185 ? 115.985 132.104 105.538 1.00 69.49  ? 129 ASN R OD1 1 
ATOM 749  N ND2 . ASN A 1 185 ? 115.026 133.151 103.808 1.00 69.49  ? 129 ASN R ND2 1 
ATOM 750  N N   . PHE A 1 186 ? 119.373 131.428 101.320 1.00 69.49  ? 130 PHE R N   1 
ATOM 751  C CA  . PHE A 1 186 ? 120.370 130.651 100.588 1.00 69.49  ? 130 PHE R CA  1 
ATOM 752  C C   . PHE A 1 186 ? 121.768 130.891 101.148 1.00 69.49  ? 130 PHE R C   1 
ATOM 753  O O   . PHE A 1 186 ? 122.499 129.942 101.483 1.00 69.49  ? 130 PHE R O   1 
ATOM 754  C CB  . PHE A 1 186 ? 120.303 131.021 99.105  1.00 69.49  ? 130 PHE R CB  1 
ATOM 755  C CG  . PHE A 1 186 ? 121.578 130.780 98.352  1.00 69.49  ? 130 PHE R CG  1 
ATOM 756  C CD1 . PHE A 1 186 ? 122.037 129.495 98.129  1.00 69.49  ? 130 PHE R CD1 1 
ATOM 757  C CD2 . PHE A 1 186 ? 122.310 131.841 97.855  1.00 69.49  ? 130 PHE R CD2 1 
ATOM 758  C CE1 . PHE A 1 186 ? 123.206 129.277 97.430  1.00 69.49  ? 130 PHE R CE1 1 
ATOM 759  C CE2 . PHE A 1 186 ? 123.479 131.627 97.158  1.00 69.49  ? 130 PHE R CE2 1 
ATOM 760  C CZ  . PHE A 1 186 ? 123.927 130.345 96.946  1.00 69.49  ? 130 PHE R CZ  1 
ATOM 761  N N   . TYR A 1 187 ? 122.152 132.164 101.273 1.00 69.49  ? 131 TYR R N   1 
ATOM 762  C CA  . TYR A 1 187 ? 123.459 132.484 101.835 1.00 69.49  ? 131 TYR R CA  1 
ATOM 763  C C   . TYR A 1 187 ? 123.581 131.959 103.258 1.00 69.49  ? 131 TYR R C   1 
ATOM 764  O O   . TYR A 1 187 ? 124.632 131.434 103.648 1.00 69.49  ? 131 TYR R O   1 
ATOM 765  C CB  . TYR A 1 187 ? 123.686 133.993 101.807 1.00 69.49  ? 131 TYR R CB  1 
ATOM 766  C CG  . TYR A 1 187 ? 124.179 134.522 100.483 1.00 69.49  ? 131 TYR R CG  1 
ATOM 767  C CD1 . TYR A 1 187 ? 125.425 134.168 99.994  1.00 69.49  ? 131 TYR R CD1 1 
ATOM 768  C CD2 . TYR A 1 187 ? 123.401 135.384 99.727  1.00 69.49  ? 131 TYR R CD2 1 
ATOM 769  C CE1 . TYR A 1 187 ? 125.878 134.651 98.786  1.00 69.49  ? 131 TYR R CE1 1 
ATOM 770  C CE2 . TYR A 1 187 ? 123.847 135.872 98.518  1.00 69.49  ? 131 TYR R CE2 1 
ATOM 771  C CZ  . TYR A 1 187 ? 125.086 135.503 98.054  1.00 69.49  ? 131 TYR R CZ  1 
ATOM 772  O OH  . TYR A 1 187 ? 125.537 135.988 96.851  1.00 69.49  ? 131 TYR R OH  1 
ATOM 773  N N   . SER A 1 188 ? 122.518 132.101 104.052 1.00 69.49  ? 132 SER R N   1 
ATOM 774  C CA  . SER A 1 188 ? 122.557 131.625 105.428 1.00 69.49  ? 132 SER R CA  1 
ATOM 775  C C   . SER A 1 188 ? 122.795 130.126 105.482 1.00 69.49  ? 132 SER R C   1 
ATOM 776  O O   . SER A 1 188 ? 123.603 129.651 106.283 1.00 69.49  ? 132 SER R O   1 
ATOM 777  C CB  . SER A 1 188 ? 121.256 131.981 106.139 1.00 69.49  ? 132 SER R CB  1 
ATOM 778  O OG  . SER A 1 188 ? 121.162 133.376 106.340 1.00 69.49  ? 132 SER R OG  1 
ATOM 779  N N   . GLY A 1 189 ? 122.103 129.362 104.639 1.00 69.49  ? 133 GLY R N   1 
ATOM 780  C CA  . GLY A 1 189 ? 122.304 127.924 104.638 1.00 69.49  ? 133 GLY R CA  1 
ATOM 781  C C   . GLY A 1 189 ? 123.728 127.546 104.287 1.00 69.49  ? 133 GLY R C   1 
ATOM 782  O O   . GLY A 1 189 ? 124.350 126.719 104.960 1.00 69.49  ? 133 GLY R O   1 
ATOM 783  N N   . ILE A 1 190 ? 124.272 128.155 103.232 1.00 69.49  ? 134 ILE R N   1 
ATOM 784  C CA  . ILE A 1 190 ? 125.631 127.804 102.821 1.00 69.49  ? 134 ILE R CA  1 
ATOM 785  C C   . ILE A 1 190 ? 126.624 128.130 103.931 1.00 69.49  ? 134 ILE R C   1 
ATOM 786  O O   . ILE A 1 190 ? 127.485 127.311 104.292 1.00 69.49  ? 134 ILE R O   1 
ATOM 787  C CB  . ILE A 1 190 ? 126.002 128.522 101.513 1.00 69.49  ? 134 ILE R CB  1 
ATOM 788  C CG1 . ILE A 1 190 ? 125.034 128.144 100.392 1.00 69.49  ? 134 ILE R CG1 1 
ATOM 789  C CG2 . ILE A 1 190 ? 127.417 128.179 101.121 1.00 69.49  ? 134 ILE R CG2 1 
ATOM 790  C CD1 . ILE A 1 190 ? 125.175 126.724 99.905  1.00 69.49  ? 134 ILE R CD1 1 
ATOM 791  N N   . LEU A 1 191 ? 126.519 129.332 104.499 1.00 69.49  ? 135 LEU R N   1 
ATOM 792  C CA  . LEU A 1 191 ? 127.490 129.738 105.506 1.00 69.49  ? 135 LEU R CA  1 
ATOM 793  C C   . LEU A 1 191 ? 127.317 128.953 106.799 1.00 69.49  ? 135 LEU R C   1 
ATOM 794  O O   . LEU A 1 191 ? 128.295 128.722 107.515 1.00 69.49  ? 135 LEU R O   1 
ATOM 795  C CB  . LEU A 1 191 ? 127.375 131.238 105.757 1.00 45.48  ? 135 LEU R CB  1 
ATOM 796  C CG  . LEU A 1 191 ? 127.660 132.124 104.539 1.00 45.48  ? 135 LEU R CG  1 
ATOM 797  C CD1 . LEU A 1 191 ? 127.595 133.586 104.924 1.00 45.48  ? 135 LEU R CD1 1 
ATOM 798  C CD2 . LEU A 1 191 ? 129.008 131.800 103.919 1.00 45.48  ? 135 LEU R CD2 1 
ATOM 799  N N   . LEU A 1 192 ? 126.097 128.513 107.108 1.00 69.49  ? 136 LEU R N   1 
ATOM 800  C CA  . LEU A 1 192 ? 125.899 127.656 108.269 1.00 69.49  ? 136 LEU R CA  1 
ATOM 801  C C   . LEU A 1 192 ? 126.508 126.281 108.053 1.00 69.49  ? 136 LEU R C   1 
ATOM 802  O O   . LEU A 1 192 ? 127.035 125.686 108.997 1.00 69.49  ? 136 LEU R O   1 
ATOM 803  C CB  . LEU A 1 192 ? 124.408 127.536 108.579 1.00 69.49  ? 136 LEU R CB  1 
ATOM 804  C CG  . LEU A 1 192 ? 123.753 128.708 109.315 1.00 69.49  ? 136 LEU R CG  1 
ATOM 805  C CD1 . LEU A 1 192 ? 122.352 128.339 109.724 1.00 69.49  ? 136 LEU R CD1 1 
ATOM 806  C CD2 . LEU A 1 192 ? 124.552 129.123 110.535 1.00 69.49  ? 136 LEU R CD2 1 
ATOM 807  N N   . LEU A 1 193 ? 126.442 125.755 106.830 1.00 69.49  ? 137 LEU R N   1 
ATOM 808  C CA  . LEU A 1 193 ? 127.146 124.509 106.546 1.00 69.49  ? 137 LEU R CA  1 
ATOM 809  C C   . LEU A 1 193 ? 128.646 124.678 106.752 1.00 69.49  ? 137 LEU R C   1 
ATOM 810  O O   . LEU A 1 193 ? 129.306 123.808 107.336 1.00 69.49  ? 137 LEU R O   1 
ATOM 811  C CB  . LEU A 1 193 ? 126.856 124.050 105.120 1.00 69.49  ? 137 LEU R CB  1 
ATOM 812  C CG  . LEU A 1 193 ? 125.423 123.646 104.773 1.00 69.49  ? 137 LEU R CG  1 
ATOM 813  C CD1 . LEU A 1 193 ? 125.425 122.793 103.527 1.00 69.49  ? 137 LEU R CD1 1 
ATOM 814  C CD2 . LEU A 1 193 ? 124.751 122.913 105.916 1.00 69.49  ? 137 LEU R CD2 1 
ATOM 815  N N   . ALA A 1 194 ? 129.200 125.798 106.287 1.00 69.49  ? 138 ALA R N   1 
ATOM 816  C CA  . ALA A 1 194 ? 130.624 126.047 106.505 1.00 69.49  ? 138 ALA R CA  1 
ATOM 817  C C   . ALA A 1 194 ? 130.951 126.156 107.993 1.00 69.49  ? 138 ALA R C   1 
ATOM 818  O O   . ALA A 1 194 ? 131.989 125.658 108.449 1.00 69.49  ? 138 ALA R O   1 
ATOM 819  C CB  . ALA A 1 194 ? 131.054 127.313 105.769 1.00 69.49  ? 138 ALA R CB  1 
ATOM 820  N N   . CYS A 1 195 ? 130.085 126.820 108.763 1.00 69.49  ? 139 CYS R N   1 
ATOM 821  C CA  . CYS A 1 195 ? 130.306 126.941 110.201 1.00 69.49  ? 139 CYS R CA  1 
ATOM 822  C C   . CYS A 1 195 ? 130.272 125.584 110.887 1.00 69.49  ? 139 CYS R C   1 
ATOM 823  O O   . CYS A 1 195 ? 131.093 125.308 111.767 1.00 69.49  ? 139 CYS R O   1 
ATOM 824  C CB  . CYS A 1 195 ? 129.261 127.867 110.817 1.00 69.49  ? 139 CYS R CB  1 
ATOM 825  S SG  . CYS A 1 195 ? 129.545 129.618 110.520 1.00 69.49  ? 139 CYS R SG  1 
ATOM 826  N N   . ILE A 1 196 ? 129.319 124.732 110.515 1.00 69.49  ? 140 ILE R N   1 
ATOM 827  C CA  . ILE A 1 196 ? 129.260 123.389 111.083 1.00 69.49  ? 140 ILE R CA  1 
ATOM 828  C C   . ILE A 1 196 ? 130.537 122.629 110.757 1.00 69.49  ? 140 ILE R C   1 
ATOM 829  O O   . ILE A 1 196 ? 131.079 121.898 111.596 1.00 69.49  ? 140 ILE R O   1 
ATOM 830  C CB  . ILE A 1 196 ? 128.016 122.650 110.561 1.00 69.49  ? 140 ILE R CB  1 
ATOM 831  C CG1 . ILE A 1 196 ? 126.752 123.221 111.201 1.00 69.49  ? 140 ILE R CG1 1 
ATOM 832  C CG2 . ILE A 1 196 ? 128.125 121.173 110.852 1.00 69.49  ? 140 ILE R CG2 1 
ATOM 833  C CD1 . ILE A 1 196 ? 125.475 122.809 110.509 1.00 69.49  ? 140 ILE R CD1 1 
ATOM 834  N N   . SER A 1 197 ? 131.031 122.783 109.530 1.00 69.49  ? 141 SER R N   1 
ATOM 835  C CA  . SER A 1 197 ? 132.280 122.132 109.152 1.00 69.49  ? 141 SER R CA  1 
ATOM 836  C C   . SER A 1 197 ? 133.433 122.584 110.037 1.00 69.49  ? 141 SER R C   1 
ATOM 837  O O   . SER A 1 197 ? 134.211 121.758 110.529 1.00 69.49  ? 141 SER R O   1 
ATOM 838  C CB  . SER A 1 197 ? 132.589 122.430 107.691 1.00 69.49  ? 141 SER R CB  1 
ATOM 839  O OG  . SER A 1 197 ? 133.791 121.807 107.300 1.00 69.49  ? 141 SER R OG  1 
ATOM 840  N N   . VAL A 1 198 ? 133.565 123.894 110.243 1.00 69.49  ? 142 VAL R N   1 
ATOM 841  C CA  . VAL A 1 198 ? 134.656 124.400 111.073 1.00 69.49  ? 142 VAL R CA  1 
ATOM 842  C C   . VAL A 1 198 ? 134.511 123.901 112.503 1.00 69.49  ? 142 VAL R C   1 
ATOM 843  O O   . VAL A 1 198 ? 135.501 123.579 113.169 1.00 69.49  ? 142 VAL R O   1 
ATOM 844  C CB  . VAL A 1 198 ? 134.706 125.937 111.022 1.00 69.49  ? 142 VAL R CB  1 
ATOM 845  C CG1 . VAL A 1 198 ? 135.781 126.455 111.959 1.00 69.49  ? 142 VAL R CG1 1 
ATOM 846  C CG2 . VAL A 1 198 ? 134.954 126.418 109.606 1.00 69.49  ? 142 VAL R CG2 1 
ATOM 847  N N   . ASP A 1 199 ? 133.278 123.847 113.001 1.00 69.49  ? 143 ASP R N   1 
ATOM 848  C CA  . ASP A 1 199 ? 133.039 123.366 114.356 1.00 69.49  ? 143 ASP R CA  1 
ATOM 849  C C   . ASP A 1 199 ? 133.496 121.925 114.514 1.00 69.49  ? 143 ASP R C   1 
ATOM 850  O O   . ASP A 1 199 ? 134.181 121.581 115.483 1.00 69.49  ? 143 ASP R O   1 
ATOM 851  C CB  . ASP A 1 199 ? 131.555 123.494 114.688 1.00 69.49  ? 143 ASP R CB  1 
ATOM 852  C CG  . ASP A 1 199 ? 131.240 123.096 116.106 1.00 69.49  ? 143 ASP R CG  1 
ATOM 853  O OD1 . ASP A 1 199 ? 132.181 122.784 116.860 1.00 69.49  ? 143 ASP R OD1 1 
ATOM 854  O OD2 . ASP A 1 199 ? 130.048 123.091 116.472 1.00 69.49  ? 143 ASP R OD2 1 
ATOM 855  N N   . ARG A 1 200 ? 133.124 121.064 113.568 1.00 69.49  ? 144 ARG R N   1 
ATOM 856  C CA  . ARG A 1 200 ? 133.535 119.668 113.650 1.00 69.49  ? 144 ARG R CA  1 
ATOM 857  C C   . ARG A 1 200 ? 135.047 119.536 113.532 1.00 69.49  ? 144 ARG R C   1 
ATOM 858  O O   . ARG A 1 200 ? 135.663 118.718 114.225 1.00 69.49  ? 144 ARG R O   1 
ATOM 859  C CB  . ARG A 1 200 ? 132.829 118.855 112.571 1.00 69.49  ? 144 ARG R CB  1 
ATOM 860  C CG  . ARG A 1 200 ? 131.346 118.720 112.822 1.00 69.49  ? 144 ARG R CG  1 
ATOM 861  C CD  . ARG A 1 200 ? 130.625 118.114 111.652 1.00 69.49  ? 144 ARG R CD  1 
ATOM 862  N NE  . ARG A 1 200 ? 129.219 117.886 111.956 1.00 69.49  ? 144 ARG R NE  1 
ATOM 863  C CZ  . ARG A 1 200 ? 128.340 117.386 111.100 1.00 69.49  ? 144 ARG R CZ  1 
ATOM 864  N NH1 . ARG A 1 200 ? 128.689 117.041 109.873 1.00 69.49  ? 144 ARG R NH1 1 
ATOM 865  N NH2 . ARG A 1 200 ? 127.079 117.223 111.487 1.00 69.49  ? 144 ARG R NH2 1 
ATOM 866  N N   . TYR A 1 201 ? 135.665 120.338 112.665 1.00 69.49  ? 145 TYR R N   1 
ATOM 867  C CA  . TYR A 1 201 ? 137.121 120.344 112.579 1.00 69.49  ? 145 TYR R CA  1 
ATOM 868  C C   . TYR A 1 201 ? 137.741 120.645 113.934 1.00 69.49  ? 145 TYR R C   1 
ATOM 869  O O   . TYR A 1 201 ? 138.610 119.909 114.411 1.00 69.49  ? 145 TYR R O   1 
ATOM 870  C CB  . TYR A 1 201 ? 137.577 121.375 111.551 1.00 69.49  ? 145 TYR R CB  1 
ATOM 871  C CG  . TYR A 1 201 ? 139.060 121.654 111.568 1.00 69.49  ? 145 TYR R CG  1 
ATOM 872  C CD1 . TYR A 1 201 ? 139.961 120.736 111.064 1.00 69.49  ? 145 TYR R CD1 1 
ATOM 873  C CD2 . TYR A 1 201 ? 139.557 122.834 112.088 1.00 69.49  ? 145 TYR R CD2 1 
ATOM 874  C CE1 . TYR A 1 201 ? 141.311 120.986 111.075 1.00 69.49  ? 145 TYR R CE1 1 
ATOM 875  C CE2 . TYR A 1 201 ? 140.907 123.089 112.106 1.00 69.49  ? 145 TYR R CE2 1 
ATOM 876  C CZ  . TYR A 1 201 ? 141.778 122.161 111.597 1.00 69.49  ? 145 TYR R CZ  1 
ATOM 877  O OH  . TYR A 1 201 ? 143.127 122.408 111.608 1.00 69.49  ? 145 TYR R OH  1 
ATOM 878  N N   . LEU A 1 202 ? 137.297 121.726 114.574 1.00 69.49  ? 146 LEU R N   1 
ATOM 879  C CA  . LEU A 1 202 ? 137.860 122.113 115.861 1.00 69.49  ? 146 LEU R CA  1 
ATOM 880  C C   . LEU A 1 202 ? 137.596 121.077 116.939 1.00 69.49  ? 146 LEU R C   1 
ATOM 881  O O   . LEU A 1 202 ? 138.422 120.917 117.841 1.00 69.49  ? 146 LEU R O   1 
ATOM 882  C CB  . LEU A 1 202 ? 137.293 123.460 116.303 1.00 69.49  ? 146 LEU R CB  1 
ATOM 883  C CG  . LEU A 1 202 ? 137.860 124.719 115.649 1.00 69.49  ? 146 LEU R CG  1 
ATOM 884  C CD1 . LEU A 1 202 ? 137.212 125.940 116.250 1.00 69.49  ? 146 LEU R CD1 1 
ATOM 885  C CD2 . LEU A 1 202 ? 139.364 124.792 115.805 1.00 69.49  ? 146 LEU R CD2 1 
ATOM 886  N N   . ALA A 1 203 ? 136.463 120.386 116.878 1.00 69.49  ? 147 ALA R N   1 
ATOM 887  C CA  . ALA A 1 203 ? 136.124 119.398 117.891 1.00 69.49  ? 147 ALA R CA  1 
ATOM 888  C C   . ALA A 1 203 ? 136.898 118.102 117.737 1.00 69.49  ? 147 ALA R C   1 
ATOM 889  O O   . ALA A 1 203 ? 137.196 117.449 118.740 1.00 69.49  ? 147 ALA R O   1 
ATOM 890  C CB  . ALA A 1 203 ? 134.628 119.094 117.847 1.00 69.49  ? 147 ALA R CB  1 
ATOM 891  N N   . ILE A 1 204 ? 137.227 117.707 116.515 1.00 69.49  ? 148 ILE R N   1 
ATOM 892  C CA  . ILE A 1 204 ? 137.871 116.424 116.258 1.00 69.49  ? 148 ILE R CA  1 
ATOM 893  C C   . ILE A 1 204 ? 139.379 116.568 116.122 1.00 69.49  ? 148 ILE R C   1 
ATOM 894  O O   . ILE A 1 204 ? 140.137 115.874 116.796 1.00 69.49  ? 148 ILE R O   1 
ATOM 895  C CB  . ILE A 1 204 ? 137.254 115.770 115.003 1.00 69.49  ? 148 ILE R CB  1 
ATOM 896  C CG1 . ILE A 1 204 ? 135.779 115.467 115.254 1.00 69.49  ? 148 ILE R CG1 1 
ATOM 897  C CG2 . ILE A 1 204 ? 138.001 114.511 114.649 1.00 69.49  ? 148 ILE R CG2 1 
ATOM 898  C CD1 . ILE A 1 204 ? 135.010 115.113 114.022 1.00 69.49  ? 148 ILE R CD1 1 
ATOM 899  N N   . VAL A 1 205 ? 139.836 117.472 115.255 1.00 69.49  ? 149 VAL R N   1 
ATOM 900  C CA  . VAL A 1 205 ? 141.270 117.608 115.018 1.00 69.49  ? 149 VAL R CA  1 
ATOM 901  C C   . VAL A 1 205 ? 141.960 118.181 116.246 1.00 69.49  ? 149 VAL R C   1 
ATOM 902  O O   . VAL A 1 205 ? 142.888 117.577 116.793 1.00 69.49  ? 149 VAL R O   1 
ATOM 903  C CB  . VAL A 1 205 ? 141.528 118.472 113.773 1.00 69.49  ? 149 VAL R CB  1 
ATOM 904  C CG1 . VAL A 1 205 ? 143.015 118.597 113.517 1.00 69.49  ? 149 VAL R CG1 1 
ATOM 905  C CG2 . VAL A 1 205 ? 140.837 117.870 112.575 1.00 69.49  ? 149 VAL R CG2 1 
ATOM 906  N N   . HIS A 1 206 ? 141.523 119.351 116.694 1.00 69.49  ? 150 HIS R N   1 
ATOM 907  C CA  . HIS A 1 206 ? 142.063 119.981 117.898 1.00 69.49  ? 150 HIS R CA  1 
ATOM 908  C C   . HIS A 1 206 ? 141.249 119.609 119.127 1.00 69.49  ? 150 HIS R C   1 
ATOM 909  O O   . HIS A 1 206 ? 140.766 120.469 119.850 1.00 69.49  ? 150 HIS R O   1 
ATOM 910  C CB  . HIS A 1 206 ? 142.115 121.493 117.728 1.00 69.49  ? 150 HIS R CB  1 
ATOM 911  C CG  . HIS A 1 206 ? 142.934 121.945 116.562 1.00 69.49  ? 150 HIS R CG  1 
ATOM 912  N ND1 . HIS A 1 206 ? 144.263 122.283 116.676 1.00 69.49  ? 150 HIS R ND1 1 
ATOM 913  C CD2 . HIS A 1 206 ? 142.601 122.155 115.268 1.00 69.49  ? 150 HIS R CD2 1 
ATOM 914  C CE1 . HIS A 1 206 ? 144.723 122.652 115.495 1.00 69.49  ? 150 HIS R CE1 1 
ATOM 915  N NE2 . HIS A 1 206 ? 143.733 122.587 114.625 1.00 69.49  ? 150 HIS R NE2 1 
ATOM 916  N N   . ALA A 1 207 ? 141.071 118.315 119.373 1.00 69.49  ? 151 ALA R N   1 
ATOM 917  C CA  . ALA A 1 207 ? 140.385 117.896 120.585 1.00 69.49  ? 151 ALA R CA  1 
ATOM 918  C C   . ALA A 1 207 ? 141.296 118.015 121.795 1.00 69.49  ? 151 ALA R C   1 
ATOM 919  O O   . ALA A 1 207 ? 140.833 118.328 122.897 1.00 69.49  ? 151 ALA R O   1 
ATOM 920  C CB  . ALA A 1 207 ? 139.881 116.464 120.436 1.00 69.49  ? 151 ALA R CB  1 
ATOM 921  N N   . THR A 1 208 ? 142.592 117.770 121.608 1.00 69.49  ? 152 THR R N   1 
ATOM 922  C CA  . THR A 1 208 ? 143.551 117.881 122.698 1.00 69.49  ? 152 THR R CA  1 
ATOM 923  C C   . THR A 1 208 ? 144.062 119.302 122.890 1.00 69.49  ? 152 THR R C   1 
ATOM 924  O O   . THR A 1 208 ? 144.598 119.611 123.959 1.00 69.49  ? 152 THR R O   1 
ATOM 925  C CB  . THR A 1 208 ? 144.738 116.949 122.448 1.00 69.49  ? 152 THR R CB  1 
ATOM 926  O OG1 . THR A 1 208 ? 144.264 115.626 122.173 1.00 69.49  ? 152 THR R OG1 1 
ATOM 927  C CG2 . THR A 1 208 ? 145.660 116.914 123.658 1.00 69.49  ? 152 THR R CG2 1 
ATOM 928  N N   . ARG A 1 209 ? 143.906 120.169 121.895 1.00 75.15  ? 153 ARG R N   1 
ATOM 929  C CA  . ARG A 1 209 ? 144.435 121.519 121.971 1.00 75.15  ? 153 ARG R CA  1 
ATOM 930  C C   . ARG A 1 209 ? 143.394 122.459 122.573 1.00 75.15  ? 153 ARG R C   1 
ATOM 931  O O   . ARG A 1 209 ? 142.227 122.107 122.755 1.00 75.15  ? 153 ARG R O   1 
ATOM 932  C CB  . ARG A 1 209 ? 144.868 122.004 120.596 1.00 30.00  ? 153 ARG R CB  1 
ATOM 933  N N   . THR A 1 210 ? 143.828 123.675 122.892 1.00 87.74  ? 154 THR R N   1 
ATOM 934  C CA  . THR A 1 210 ? 142.974 124.678 123.513 1.00 87.74  ? 154 THR R CA  1 
ATOM 935  C C   . THR A 1 210 ? 142.109 125.424 122.507 1.00 87.74  ? 154 THR R C   1 
ATOM 936  O O   . THR A 1 210 ? 141.214 126.171 122.916 1.00 87.74  ? 154 THR R O   1 
ATOM 937  C CB  . THR A 1 210 ? 143.826 125.688 124.287 1.00 87.74  ? 154 THR R CB  1 
ATOM 938  O OG1 . THR A 1 210 ? 144.736 126.333 123.388 1.00 87.74  ? 154 THR R OG1 1 
ATOM 939  C CG2 . THR A 1 210 ? 144.609 124.993 125.389 1.00 87.74  ? 154 THR R CG2 1 
ATOM 940  N N   . LEU A 1 211 ? 142.352 125.244 121.209 1.00 69.49  ? 155 LEU R N   1 
ATOM 941  C CA  . LEU A 1 211 ? 141.558 125.929 120.201 1.00 69.49  ? 155 LEU R CA  1 
ATOM 942  C C   . LEU A 1 211 ? 140.111 125.459 120.192 1.00 69.49  ? 155 LEU R C   1 
ATOM 943  O O   . LEU A 1 211 ? 139.224 126.232 119.815 1.00 69.49  ? 155 LEU R O   1 
ATOM 944  C CB  . LEU A 1 211 ? 142.189 125.726 118.821 1.00 65.27  ? 155 LEU R CB  1 
ATOM 945  C CG  . LEU A 1 211 ? 141.752 126.686 117.714 1.00 65.27  ? 155 LEU R CG  1 
ATOM 946  C CD1 . LEU A 1 211 ? 142.078 128.120 118.078 1.00 65.27  ? 155 LEU R CD1 1 
ATOM 947  C CD2 . LEU A 1 211 ? 142.411 126.319 116.402 1.00 65.27  ? 155 LEU R CD2 1 
ATOM 948  N N   . THR A 1 212 ? 139.850 124.221 120.618 1.00 69.49  ? 156 THR R N   1 
ATOM 949  C CA  . THR A 1 212 ? 138.481 123.724 120.680 1.00 69.49  ? 156 THR R CA  1 
ATOM 950  C C   . THR A 1 212 ? 137.594 124.585 121.566 1.00 69.49  ? 156 THR R C   1 
ATOM 951  O O   . THR A 1 212 ? 136.386 124.658 121.325 1.00 69.49  ? 156 THR R O   1 
ATOM 952  C CB  . THR A 1 212 ? 138.462 122.282 121.191 1.00 64.58  ? 156 THR R CB  1 
ATOM 953  O OG1 . THR A 1 212 ? 137.121 121.780 121.168 1.00 64.58  ? 156 THR R OG1 1 
ATOM 954  C CG2 . THR A 1 212 ? 139.000 122.204 122.611 1.00 64.58  ? 156 THR R CG2 1 
ATOM 955  N N   . GLN A 1 213 ? 138.163 125.240 122.576 1.00 72.83  ? 157 GLN R N   1 
ATOM 956  C CA  . GLN A 1 213 ? 137.397 126.113 123.453 1.00 72.83  ? 157 GLN R CA  1 
ATOM 957  C C   . GLN A 1 213 ? 136.814 127.311 122.720 1.00 72.83  ? 157 GLN R C   1 
ATOM 958  O O   . GLN A 1 213 ? 135.896 127.949 123.244 1.00 72.83  ? 157 GLN R O   1 
ATOM 959  C CB  . GLN A 1 213 ? 138.277 126.608 124.603 1.00 72.83  ? 157 GLN R CB  1 
ATOM 960  C CG  . GLN A 1 213 ? 139.009 125.512 125.369 1.00 72.83  ? 157 GLN R CG  1 
ATOM 961  C CD  . GLN A 1 213 ? 138.082 124.448 125.918 1.00 72.83  ? 157 GLN R CD  1 
ATOM 962  O OE1 . GLN A 1 213 ? 137.564 123.616 125.176 1.00 72.83  ? 157 GLN R OE1 1 
ATOM 963  N NE2 . GLN A 1 213 ? 137.868 124.470 127.229 1.00 72.83  ? 157 GLN R NE2 1 
ATOM 964  N N   . LYS A 1 214 ? 137.318 127.633 121.530 1.00 69.49  ? 158 LYS R N   1 
ATOM 965  C CA  . LYS A 1 214 ? 136.834 128.766 120.755 1.00 69.49  ? 158 LYS R CA  1 
ATOM 966  C C   . LYS A 1 214 ? 135.538 128.457 120.026 1.00 69.49  ? 158 LYS R C   1 
ATOM 967  O O   . LYS A 1 214 ? 134.957 129.353 119.407 1.00 69.49  ? 158 LYS R O   1 
ATOM 968  C CB  . LYS A 1 214 ? 137.898 129.213 119.751 1.00 65.78  ? 158 LYS R CB  1 
ATOM 969  C CG  . LYS A 1 214 ? 139.197 129.667 120.392 1.00 65.78  ? 158 LYS R CG  1 
ATOM 970  C CD  . LYS A 1 214 ? 139.787 130.860 119.663 1.00 65.78  ? 158 LYS R CD  1 
ATOM 971  C CE  . LYS A 1 214 ? 140.979 131.431 120.412 1.00 65.78  ? 158 LYS R CE  1 
ATOM 972  N NZ  . LYS A 1 214 ? 142.096 130.452 120.504 1.00 65.78  ? 158 LYS R NZ  1 
ATOM 973  N N   . ARG A 1 215 ? 135.074 127.213 120.081 1.00 69.49  ? 159 ARG R N   1 
ATOM 974  C CA  . ARG A 1 215 ? 133.840 126.808 119.430 1.00 69.49  ? 159 ARG R CA  1 
ATOM 975  C C   . ARG A 1 215 ? 132.624 127.006 120.326 1.00 69.49  ? 159 ARG R C   1 
ATOM 976  O O   . ARG A 1 215 ? 131.547 126.491 120.016 1.00 69.49  ? 159 ARG R O   1 
ATOM 977  C CB  . ARG A 1 215 ? 133.953 125.351 118.972 1.00 60.41  ? 159 ARG R CB  1 
ATOM 978  C CG  . ARG A 1 215 ? 133.581 124.313 120.009 1.00 60.41  ? 159 ARG R CG  1 
ATOM 979  C CD  . ARG A 1 215 ? 133.943 122.915 119.537 1.00 60.41  ? 159 ARG R CD  1 
ATOM 980  N NE  . ARG A 1 215 ? 133.283 121.887 120.335 1.00 60.41  ? 159 ARG R NE  1 
ATOM 981  C CZ  . ARG A 1 215 ? 132.312 121.091 119.904 1.00 60.41  ? 159 ARG R CZ  1 
ATOM 982  N NH1 . ARG A 1 215 ? 131.830 121.183 118.676 1.00 60.41  ? 159 ARG R NH1 1 
ATOM 983  N NH2 . ARG A 1 215 ? 131.804 120.184 120.732 1.00 60.41  ? 159 ARG R NH2 1 
ATOM 984  N N   . TYR A 1 216 ? 132.772 127.746 121.423 1.00 71.04  ? 160 TYR R N   1 
ATOM 985  C CA  . TYR A 1 216 ? 131.666 128.101 122.299 1.00 71.04  ? 160 TYR R CA  1 
ATOM 986  C C   . TYR A 1 216 ? 131.040 129.440 121.930 1.00 71.04  ? 160 TYR R C   1 
ATOM 987  O O   . TYR A 1 216 ? 130.215 129.959 122.689 1.00 71.04  ? 160 TYR R O   1 
ATOM 988  C CB  . TYR A 1 216 ? 132.138 128.127 123.752 1.00 71.04  ? 160 TYR R CB  1 
ATOM 989  C CG  . TYR A 1 216 ? 132.651 126.794 124.250 1.00 71.04  ? 160 TYR R CG  1 
ATOM 990  C CD1 . TYR A 1 216 ? 131.975 125.616 123.963 1.00 71.04  ? 160 TYR R CD1 1 
ATOM 991  C CD2 . TYR A 1 216 ? 133.810 126.714 125.010 1.00 71.04  ? 160 TYR R CD2 1 
ATOM 992  C CE1 . TYR A 1 216 ? 132.439 124.397 124.412 1.00 71.04  ? 160 TYR R CE1 1 
ATOM 993  C CE2 . TYR A 1 216 ? 134.281 125.498 125.467 1.00 71.04  ? 160 TYR R CE2 1 
ATOM 994  C CZ  . TYR A 1 216 ? 133.591 124.343 125.164 1.00 71.04  ? 160 TYR R CZ  1 
ATOM 995  O OH  . TYR A 1 216 ? 134.055 123.129 125.615 1.00 71.04  ? 160 TYR R OH  1 
ATOM 996  N N   . LEU A 1 217 ? 131.412 130.007 120.782 1.00 69.49  ? 161 LEU R N   1 
ATOM 997  C CA  . LEU A 1 217 ? 130.896 131.285 120.308 1.00 69.49  ? 161 LEU R CA  1 
ATOM 998  C C   . LEU A 1 217 ? 129.762 131.108 119.306 1.00 69.49  ? 161 LEU R C   1 
ATOM 999  O O   . LEU A 1 217 ? 129.618 131.916 118.384 1.00 69.49  ? 161 LEU R O   1 
ATOM 1000 C CB  . LEU A 1 217 ? 132.024 132.102 119.681 1.00 69.49  ? 161 LEU R CB  1 
ATOM 1001 C CG  . LEU A 1 217 ? 133.345 132.111 120.450 1.00 69.49  ? 161 LEU R CG  1 
ATOM 1002 C CD1 . LEU A 1 217 ? 134.396 132.920 119.711 1.00 69.49  ? 161 LEU R CD1 1 
ATOM 1003 C CD2 . LEU A 1 217 ? 133.130 132.659 121.850 1.00 69.49  ? 161 LEU R CD2 1 
ATOM 1004 N N   . VAL A 1 218 ? 128.952 130.061 119.467 1.00 69.49  ? 162 VAL R N   1 
ATOM 1005 C CA  . VAL A 1 218 ? 127.969 129.722 118.442 1.00 69.49  ? 162 VAL R CA  1 
ATOM 1006 C C   . VAL A 1 218 ? 126.988 130.863 118.233 1.00 69.49  ? 162 VAL R C   1 
ATOM 1007 O O   . VAL A 1 218 ? 126.630 131.186 117.097 1.00 69.49  ? 162 VAL R O   1 
ATOM 1008 C CB  . VAL A 1 218 ? 127.231 128.423 118.806 1.00 58.99  ? 162 VAL R CB  1 
ATOM 1009 C CG1 . VAL A 1 218 ? 128.188 127.277 118.831 1.00 58.99  ? 162 VAL R CG1 1 
ATOM 1010 C CG2 . VAL A 1 218 ? 126.516 128.556 120.143 1.00 58.99  ? 162 VAL R CG2 1 
ATOM 1011 N N   . LYS A 1 219 ? 126.515 131.473 119.316 1.00 69.49  ? 163 LYS R N   1 
ATOM 1012 C CA  . LYS A 1 219 ? 125.460 132.470 119.184 1.00 69.49  ? 163 LYS R CA  1 
ATOM 1013 C C   . LYS A 1 219 ? 125.924 133.644 118.332 1.00 69.49  ? 163 LYS R C   1 
ATOM 1014 O O   . LYS A 1 219 ? 125.236 134.056 117.390 1.00 69.49  ? 163 LYS R O   1 
ATOM 1015 C CB  . LYS A 1 219 ? 125.018 132.936 120.571 1.00 62.20  ? 163 LYS R CB  1 
ATOM 1016 C CG  . LYS A 1 219 ? 123.747 133.774 120.575 1.00 62.20  ? 163 LYS R CG  1 
ATOM 1017 C CD  . LYS A 1 219 ? 123.329 134.236 121.979 1.00 62.20  ? 163 LYS R CD  1 
ATOM 1018 C CE  . LYS A 1 219 ? 123.416 133.134 123.036 1.00 62.20  ? 163 LYS R CE  1 
ATOM 1019 N NZ  . LYS A 1 219 ? 123.060 133.637 124.393 1.00 62.20  ? 163 LYS R NZ  1 
ATOM 1020 N N   . PHE A 1 220 ? 127.114 134.170 118.619 1.00 69.49  ? 164 PHE R N   1 
ATOM 1021 C CA  . PHE A 1 220 ? 127.589 135.341 117.893 1.00 69.49  ? 164 PHE R CA  1 
ATOM 1022 C C   . PHE A 1 220 ? 128.073 134.972 116.497 1.00 69.49  ? 164 PHE R C   1 
ATOM 1023 O O   . PHE A 1 220 ? 127.940 135.769 115.565 1.00 69.49  ? 164 PHE R O   1 
ATOM 1024 C CB  . PHE A 1 220 ? 128.687 136.037 118.696 1.00 60.37  ? 164 PHE R CB  1 
ATOM 1025 C CG  . PHE A 1 220 ? 128.212 136.585 120.020 1.00 60.37  ? 164 PHE R CG  1 
ATOM 1026 C CD1 . PHE A 1 220 ? 126.859 136.768 120.275 1.00 60.37  ? 164 PHE R CD1 1 
ATOM 1027 C CD2 . PHE A 1 220 ? 129.117 136.903 121.017 1.00 60.37  ? 164 PHE R CD2 1 
ATOM 1028 C CE1 . PHE A 1 220 ? 126.422 137.264 121.485 1.00 60.37  ? 164 PHE R CE1 1 
ATOM 1029 C CE2 . PHE A 1 220 ? 128.679 137.400 122.235 1.00 60.37  ? 164 PHE R CE2 1 
ATOM 1030 C CZ  . PHE A 1 220 ? 127.330 137.579 122.466 1.00 60.37  ? 164 PHE R CZ  1 
ATOM 1031 N N   . ILE A 1 221 ? 128.618 133.769 116.318 1.00 69.49  ? 165 ILE R N   1 
ATOM 1032 C CA  . ILE A 1 221 ? 128.985 133.334 114.973 1.00 69.49  ? 165 ILE R CA  1 
ATOM 1033 C C   . ILE A 1 221 ? 127.746 133.212 114.095 1.00 69.49  ? 165 ILE R C   1 
ATOM 1034 O O   . ILE A 1 221 ? 127.738 133.654 112.941 1.00 69.49  ? 165 ILE R O   1 
ATOM 1035 C CB  . ILE A 1 221 ? 129.774 132.015 115.030 1.00 69.49  ? 165 ILE R CB  1 
ATOM 1036 C CG1 . ILE A 1 221 ? 131.190 132.275 115.546 1.00 69.49  ? 165 ILE R CG1 1 
ATOM 1037 C CG2 . ILE A 1 221 ? 129.819 131.359 113.664 1.00 69.49  ? 165 ILE R CG2 1 
ATOM 1038 C CD1 . ILE A 1 221 ? 131.893 131.044 116.058 1.00 69.49  ? 165 ILE R CD1 1 
ATOM 1039 N N   . CYS A 1 222 ? 126.680 132.617 114.624 1.00 69.49  ? 166 CYS R N   1 
ATOM 1040 C CA  . CYS A 1 222 ? 125.443 132.486 113.863 1.00 69.49  ? 166 CYS R CA  1 
ATOM 1041 C C   . CYS A 1 222 ? 124.827 133.848 113.578 1.00 69.49  ? 166 CYS R C   1 
ATOM 1042 O O   . CYS A 1 222 ? 124.315 134.089 112.477 1.00 69.49  ? 166 CYS R O   1 
ATOM 1043 C CB  . CYS A 1 222 ? 124.464 131.601 114.632 1.00 69.49  ? 166 CYS R CB  1 
ATOM 1044 S SG  . CYS A 1 222 ? 124.985 129.877 114.747 1.00 69.49  ? 166 CYS R SG  1 
ATOM 1045 N N   . LEU A 1 223 ? 124.862 134.751 114.558 1.00 69.49  ? 167 LEU R N   1 
ATOM 1046 C CA  . LEU A 1 223 ? 124.340 136.094 114.339 1.00 69.49  ? 167 LEU R CA  1 
ATOM 1047 C C   . LEU A 1 223 ? 125.139 136.825 113.263 1.00 69.49  ? 167 LEU R C   1 
ATOM 1048 O O   . LEU A 1 223 ? 124.567 137.505 112.403 1.00 69.49  ? 167 LEU R O   1 
ATOM 1049 C CB  . LEU A 1 223 ? 124.362 136.863 115.657 1.00 69.49  ? 167 LEU R CB  1 
ATOM 1050 C CG  . LEU A 1 223 ? 123.652 138.209 115.693 1.00 69.49  ? 167 LEU R CG  1 
ATOM 1051 C CD1 . LEU A 1 223 ? 122.153 138.019 115.550 1.00 69.49  ? 167 LEU R CD1 1 
ATOM 1052 C CD2 . LEU A 1 223 ? 123.985 138.930 116.983 1.00 69.49  ? 167 LEU R CD2 1 
ATOM 1053 N N   . SER A 1 224 ? 126.464 136.681 113.286 1.00 69.49  ? 168 SER R N   1 
ATOM 1054 C CA  . SER A 1 224 ? 127.299 137.302 112.266 1.00 69.49  ? 168 SER R CA  1 
ATOM 1055 C C   . SER A 1 224 ? 127.018 136.713 110.891 1.00 69.49  ? 168 SER R C   1 
ATOM 1056 O O   . SER A 1 224 ? 127.022 137.432 109.889 1.00 69.49  ? 168 SER R O   1 
ATOM 1057 C CB  . SER A 1 224 ? 128.772 137.131 112.630 1.00 69.49  ? 168 SER R CB  1 
ATOM 1058 O OG  . SER A 1 224 ? 129.611 137.666 111.624 1.00 69.49  ? 168 SER R OG  1 
ATOM 1059 N N   . ILE A 1 225 ? 126.792 135.403 110.819 1.00 69.49  ? 169 ILE R N   1 
ATOM 1060 C CA  . ILE A 1 225 ? 126.481 134.784 109.535 1.00 69.49  ? 169 ILE R CA  1 
ATOM 1061 C C   . ILE A 1 225 ? 125.157 135.308 108.997 1.00 69.49  ? 169 ILE R C   1 
ATOM 1062 O O   . ILE A 1 225 ? 125.036 135.611 107.805 1.00 69.49  ? 169 ILE R O   1 
ATOM 1063 C CB  . ILE A 1 225 ? 126.469 133.252 109.668 1.00 69.49  ? 169 ILE R CB  1 
ATOM 1064 C CG1 . ILE A 1 225 ? 127.892 132.715 109.834 1.00 69.49  ? 169 ILE R CG1 1 
ATOM 1065 C CG2 . ILE A 1 225 ? 125.791 132.621 108.470 1.00 69.49  ? 169 ILE R CG2 1 
ATOM 1066 C CD1 . ILE A 1 225 ? 128.846 133.096 108.724 1.00 69.49  ? 169 ILE R CD1 1 
ATOM 1067 N N   . TRP A 1 226 ? 124.141 135.413 109.855 1.00 69.49  ? 170 TRP R N   1 
ATOM 1068 C CA  . TRP A 1 226 ? 122.872 135.975 109.405 1.00 69.49  ? 170 TRP R CA  1 
ATOM 1069 C C   . TRP A 1 226 ? 123.046 137.411 108.931 1.00 69.49  ? 170 TRP R C   1 
ATOM 1070 O O   . TRP A 1 226 ? 122.458 137.806 107.917 1.00 69.49  ? 170 TRP R O   1 
ATOM 1071 C CB  . TRP A 1 226 ? 121.835 135.905 110.525 1.00 69.49  ? 170 TRP R CB  1 
ATOM 1072 C CG  . TRP A 1 226 ? 121.162 134.569 110.638 1.00 69.49  ? 170 TRP R CG  1 
ATOM 1073 C CD1 . TRP A 1 226 ? 121.451 133.580 111.529 1.00 69.49  ? 170 TRP R CD1 1 
ATOM 1074 C CD2 . TRP A 1 226 ? 120.082 134.078 109.834 1.00 69.49  ? 170 TRP R CD2 1 
ATOM 1075 N NE1 . TRP A 1 226 ? 120.623 132.504 111.328 1.00 69.49  ? 170 TRP R NE1 1 
ATOM 1076 C CE2 . TRP A 1 226 ? 119.773 132.786 110.293 1.00 69.49  ? 170 TRP R CE2 1 
ATOM 1077 C CE3 . TRP A 1 226 ? 119.350 134.606 108.769 1.00 69.49  ? 170 TRP R CE3 1 
ATOM 1078 C CZ2 . TRP A 1 226 ? 118.766 132.016 109.726 1.00 69.49  ? 170 TRP R CZ2 1 
ATOM 1079 C CZ3 . TRP A 1 226 ? 118.350 133.837 108.208 1.00 69.49  ? 170 TRP R CZ3 1 
ATOM 1080 C CH2 . TRP A 1 226 ? 118.068 132.559 108.686 1.00 69.49  ? 170 TRP R CH2 1 
ATOM 1081 N N   . GLY A 1 227 ? 123.850 138.203 109.641 1.00 69.49  ? 171 GLY R N   1 
ATOM 1082 C CA  . GLY A 1 227 ? 124.090 139.571 109.208 1.00 69.49  ? 171 GLY R CA  1 
ATOM 1083 C C   . GLY A 1 227 ? 124.796 139.649 107.868 1.00 69.49  ? 171 GLY R C   1 
ATOM 1084 O O   . GLY A 1 227 ? 124.433 140.458 107.012 1.00 69.49  ? 171 GLY R O   1 
ATOM 1085 N N   . LEU A 1 228 ? 125.814 138.814 107.667 1.00 69.49  ? 172 LEU R N   1 
ATOM 1086 C CA  . LEU A 1 228 ? 126.525 138.806 106.393 1.00 69.49  ? 172 LEU R CA  1 
ATOM 1087 C C   . LEU A 1 228 ? 125.607 138.371 105.259 1.00 69.49  ? 172 LEU R C   1 
ATOM 1088 O O   . LEU A 1 228 ? 125.677 138.916 104.152 1.00 69.49  ? 172 LEU R O   1 
ATOM 1089 C CB  . LEU A 1 228 ? 127.743 137.889 106.483 1.00 69.49  ? 172 LEU R CB  1 
ATOM 1090 C CG  . LEU A 1 228 ? 128.607 137.760 105.229 1.00 69.49  ? 172 LEU R CG  1 
ATOM 1091 C CD1 . LEU A 1 228 ? 129.249 139.089 104.880 1.00 69.49  ? 172 LEU R CD1 1 
ATOM 1092 C CD2 . LEU A 1 228 ? 129.665 136.688 105.416 1.00 69.49  ? 172 LEU R CD2 1 
ATOM 1093 N N   . SER A 1 229 ? 124.746 137.386 105.513 1.00 69.49  ? 173 SER R N   1 
ATOM 1094 C CA  . SER A 1 229 ? 123.785 136.962 104.502 1.00 69.49  ? 173 SER R CA  1 
ATOM 1095 C C   . SER A 1 229 ? 122.829 138.093 104.150 1.00 69.49  ? 173 SER R C   1 
ATOM 1096 O O   . SER A 1 229 ? 122.522 138.320 102.976 1.00 69.49  ? 173 SER R O   1 
ATOM 1097 C CB  . SER A 1 229 ? 123.012 135.744 104.999 1.00 69.49  ? 173 SER R CB  1 
ATOM 1098 O OG  . SER A 1 229 ? 123.900 134.714 105.386 1.00 69.49  ? 173 SER R OG  1 
ATOM 1099 N N   . LEU A 1 230 ? 122.343 138.815 105.159 1.00 69.49  ? 174 LEU R N   1 
ATOM 1100 C CA  . LEU A 1 230 ? 121.480 139.958 104.881 1.00 69.49  ? 174 LEU R CA  1 
ATOM 1101 C C   . LEU A 1 230 ? 122.218 141.010 104.065 1.00 69.49  ? 174 LEU R C   1 
ATOM 1102 O O   . LEU A 1 230 ? 121.635 141.636 103.173 1.00 69.49  ? 174 LEU R O   1 
ATOM 1103 C CB  . LEU A 1 230 ? 120.965 140.560 106.186 1.00 69.49  ? 174 LEU R CB  1 
ATOM 1104 C CG  . LEU A 1 230 ? 120.057 141.781 106.041 1.00 69.49  ? 174 LEU R CG  1 
ATOM 1105 C CD1 . LEU A 1 230 ? 118.760 141.408 105.348 1.00 69.49  ? 174 LEU R CD1 1 
ATOM 1106 C CD2 . LEU A 1 230 ? 119.780 142.400 107.397 1.00 69.49  ? 174 LEU R CD2 1 
ATOM 1107 N N   . LEU A 1 231 ? 123.498 141.230 104.367 1.00 69.49  ? 175 LEU R N   1 
ATOM 1108 C CA  . LEU A 1 231 ? 124.275 142.214 103.620 1.00 69.49  ? 175 LEU R CA  1 
ATOM 1109 C C   . LEU A 1 231 ? 124.446 141.804 102.163 1.00 69.49  ? 175 LEU R C   1 
ATOM 1110 O O   . LEU A 1 231 ? 124.310 142.636 101.261 1.00 69.49  ? 175 LEU R O   1 
ATOM 1111 C CB  . LEU A 1 231 ? 125.638 142.413 104.281 1.00 69.49  ? 175 LEU R CB  1 
ATOM 1112 C CG  . LEU A 1 231 ? 126.646 143.284 103.532 1.00 69.49  ? 175 LEU R CG  1 
ATOM 1113 C CD1 . LEU A 1 231 ? 126.188 144.728 103.497 1.00 69.49  ? 175 LEU R CD1 1 
ATOM 1114 C CD2 . LEU A 1 231 ? 128.013 143.175 104.175 1.00 69.49  ? 175 LEU R CD2 1 
ATOM 1115 N N   . LEU A 1 232 ? 124.748 140.534 101.911 1.00 69.49  ? 176 LEU R N   1 
ATOM 1116 C CA  . LEU A 1 232 ? 125.010 140.057 100.558 1.00 69.49  ? 176 LEU R CA  1 
ATOM 1117 C C   . LEU A 1 232 ? 123.759 139.985 99.694  1.00 69.49  ? 176 LEU R C   1 
ATOM 1118 O O   . LEU A 1 232 ? 123.877 139.840 98.474  1.00 69.49  ? 176 LEU R O   1 
ATOM 1119 C CB  . LEU A 1 232 ? 125.668 138.676 100.601 1.00 69.49  ? 176 LEU R CB  1 
ATOM 1120 C CG  . LEU A 1 232 ? 127.147 138.612 100.977 1.00 69.49  ? 176 LEU R CG  1 
ATOM 1121 C CD1 . LEU A 1 232 ? 127.597 137.169 101.064 1.00 69.49  ? 176 LEU R CD1 1 
ATOM 1122 C CD2 . LEU A 1 232 ? 127.985 139.363 99.966  1.00 69.49  ? 176 LEU R CD2 1 
ATOM 1123 N N   . ALA A 1 233 ? 122.572 140.075 100.285 1.00 69.49  ? 177 ALA R N   1 
ATOM 1124 C CA  . ALA A 1 233 ? 121.325 140.013 99.540  1.00 69.49  ? 177 ALA R CA  1 
ATOM 1125 C C   . ALA A 1 233 ? 120.766 141.390 99.216  1.00 69.49  ? 177 ALA R C   1 
ATOM 1126 O O   . ALA A 1 233 ? 119.663 141.484 98.671  1.00 69.49  ? 177 ALA R O   1 
ATOM 1127 C CB  . ALA A 1 233 ? 120.287 139.206 100.319 1.00 69.49  ? 177 ALA R CB  1 
ATOM 1128 N N   . LEU A 1 234 ? 121.487 142.457 99.549  1.00 69.49  ? 178 LEU R N   1 
ATOM 1129 C CA  . LEU A 1 234 ? 120.987 143.796 99.252  1.00 69.49  ? 178 LEU R CA  1 
ATOM 1130 C C   . LEU A 1 234 ? 120.790 144.035 97.762  1.00 69.49  ? 178 LEU R C   1 
ATOM 1131 O O   . LEU A 1 234 ? 119.741 144.589 97.391  1.00 69.49  ? 178 LEU R O   1 
ATOM 1132 C CB  . LEU A 1 234 ? 121.934 144.848 99.842  1.00 69.49  ? 178 LEU R CB  1 
ATOM 1133 C CG  . LEU A 1 234 ? 121.852 145.105 101.348 1.00 69.49  ? 178 LEU R CG  1 
ATOM 1134 C CD1 . LEU A 1 234 ? 122.780 146.244 101.717 1.00 69.49  ? 178 LEU R CD1 1 
ATOM 1135 C CD2 . LEU A 1 234 ? 120.432 145.409 101.797 1.00 69.49  ? 178 LEU R CD2 1 
ATOM 1136 N N   . PRO A 1 235 ? 121.718 143.667 96.875  1.00 69.49  ? 179 PRO R N   1 
ATOM 1137 C CA  . PRO A 1 235 ? 121.522 143.977 95.451  1.00 69.49  ? 179 PRO R CA  1 
ATOM 1138 C C   . PRO A 1 235 ? 120.232 143.416 94.887  1.00 69.49  ? 179 PRO R C   1 
ATOM 1139 O O   . PRO A 1 235 ? 119.637 144.016 93.986  1.00 69.49  ? 179 PRO R O   1 
ATOM 1140 C CB  . PRO A 1 235 ? 122.756 143.346 94.796  1.00 69.49  ? 179 PRO R CB  1 
ATOM 1141 C CG  . PRO A 1 235 ? 123.784 143.360 95.867  1.00 69.49  ? 179 PRO R CG  1 
ATOM 1142 C CD  . PRO A 1 235 ? 123.022 143.030 97.112  1.00 69.49  ? 179 PRO R CD  1 
ATOM 1143 N N   . VAL A 1 236 ? 119.787 142.268 95.394  1.00 69.49  ? 180 VAL R N   1 
ATOM 1144 C CA  . VAL A 1 236 ? 118.515 141.700 94.960  1.00 69.49  ? 180 VAL R CA  1 
ATOM 1145 C C   . VAL A 1 236 ? 117.367 142.644 95.293  1.00 69.49  ? 180 VAL R C   1 
ATOM 1146 O O   . VAL A 1 236 ? 116.478 142.884 94.470  1.00 69.49  ? 180 VAL R O   1 
ATOM 1147 C CB  . VAL A 1 236 ? 118.312 140.315 95.597  1.00 69.49  ? 180 VAL R CB  1 
ATOM 1148 C CG1 . VAL A 1 236 ? 116.849 139.992 95.716  1.00 69.49  ? 180 VAL R CG1 1 
ATOM 1149 C CG2 . VAL A 1 236 ? 119.011 139.260 94.769  1.00 69.49  ? 180 VAL R CG2 1 
ATOM 1150 N N   . LEU A 1 237 ? 117.359 143.185 96.510  1.00 69.49  ? 181 LEU R N   1 
ATOM 1151 C CA  . LEU A 1 237 ? 116.287 144.096 96.894  1.00 69.49  ? 181 LEU R CA  1 
ATOM 1152 C C   . LEU A 1 237 ? 116.385 145.418 96.143  1.00 69.49  ? 181 LEU R C   1 
ATOM 1153 O O   . LEU A 1 237 ? 115.364 145.989 95.745  1.00 69.49  ? 181 LEU R O   1 
ATOM 1154 C CB  . LEU A 1 237 ? 116.321 144.331 98.403  1.00 69.49  ? 181 LEU R CB  1 
ATOM 1155 C CG  . LEU A 1 237 ? 115.275 145.285 98.979  1.00 69.49  ? 181 LEU R CG  1 
ATOM 1156 C CD1 . LEU A 1 237 ? 113.975 144.560 99.262  1.00 69.49  ? 181 LEU R CD1 1 
ATOM 1157 C CD2 . LEU A 1 237 ? 115.809 145.933 100.242 1.00 69.49  ? 181 LEU R CD2 1 
ATOM 1158 N N   . LEU A 1 238 ? 117.601 145.921 95.940  1.00 69.49  ? 182 LEU R N   1 
ATOM 1159 C CA  . LEU A 1 238 ? 117.761 147.260 95.384  1.00 69.49  ? 182 LEU R CA  1 
ATOM 1160 C C   . LEU A 1 238 ? 117.397 147.318 93.907  1.00 69.49  ? 182 LEU R C   1 
ATOM 1161 O O   . LEU A 1 238 ? 116.743 148.269 93.467  1.00 69.49  ? 182 LEU R O   1 
ATOM 1162 C CB  . LEU A 1 238 ? 119.198 147.740 95.580  1.00 69.49  ? 182 LEU R CB  1 
ATOM 1163 C CG  . LEU A 1 238 ? 119.667 147.926 97.020  1.00 69.49  ? 182 LEU R CG  1 
ATOM 1164 C CD1 . LEU A 1 238 ? 121.155 148.219 97.052  1.00 69.49  ? 182 LEU R CD1 1 
ATOM 1165 C CD2 . LEU A 1 238 ? 118.886 149.040 97.688  1.00 69.49  ? 182 LEU R CD2 1 
ATOM 1166 N N   . PHE A 1 239 ? 117.802 146.317 93.129  1.00 69.49  ? 183 PHE R N   1 
ATOM 1167 C CA  . PHE A 1 239 ? 117.762 146.376 91.672  1.00 69.49  ? 183 PHE R CA  1 
ATOM 1168 C C   . PHE A 1 239 ? 116.876 145.296 91.061  1.00 69.49  ? 183 PHE R C   1 
ATOM 1169 O O   . PHE A 1 239 ? 117.298 144.606 90.138  1.00 69.49  ? 183 PHE R O   1 
ATOM 1170 C CB  . PHE A 1 239 ? 119.164 146.242 91.083  1.00 69.49  ? 183 PHE R CB  1 
ATOM 1171 C CG  . PHE A 1 239 ? 120.178 147.164 91.683  1.00 69.49  ? 183 PHE R CG  1 
ATOM 1172 C CD1 . PHE A 1 239 ? 120.020 148.533 91.611  1.00 69.49  ? 183 PHE R CD1 1 
ATOM 1173 C CD2 . PHE A 1 239 ? 121.309 146.657 92.295  1.00 69.49  ? 183 PHE R CD2 1 
ATOM 1174 C CE1 . PHE A 1 239 ? 120.962 149.378 92.153  1.00 69.49  ? 183 PHE R CE1 1 
ATOM 1175 C CE2 . PHE A 1 239 ? 122.252 147.497 92.837  1.00 69.49  ? 183 PHE R CE2 1 
ATOM 1176 C CZ  . PHE A 1 239 ? 122.079 148.859 92.767  1.00 69.49  ? 183 PHE R CZ  1 
ATOM 1177 N N   . ARG A 1 240 ? 115.655 145.112 91.556  1.00 69.49  ? 184 ARG R N   1 
ATOM 1178 C CA  . ARG A 1 240 ? 114.764 144.095 91.008  1.00 69.49  ? 184 ARG R CA  1 
ATOM 1179 C C   . ARG A 1 240 ? 113.380 144.668 90.756  1.00 69.49  ? 184 ARG R C   1 
ATOM 1180 O O   . ARG A 1 240 ? 112.855 145.427 91.574  1.00 69.49  ? 184 ARG R O   1 
ATOM 1181 C CB  . ARG A 1 240 ? 114.664 142.879 91.931  1.00 69.49  ? 184 ARG R CB  1 
ATOM 1182 C CG  . ARG A 1 240 ? 115.755 141.861 91.683  1.00 69.49  ? 184 ARG R CG  1 
ATOM 1183 C CD  . ARG A 1 240 ? 115.271 140.442 91.853  1.00 69.49  ? 184 ARG R CD  1 
ATOM 1184 N NE  . ARG A 1 240 ? 116.369 139.500 91.682  1.00 69.49  ? 184 ARG R NE  1 
ATOM 1185 C CZ  . ARG A 1 240 ? 116.266 138.187 91.825  1.00 69.49  ? 184 ARG R CZ  1 
ATOM 1186 N NH1 . ARG A 1 240 ? 115.115 137.613 92.134  1.00 69.49  ? 184 ARG R NH1 1 
ATOM 1187 N NH2 . ARG A 1 240 ? 117.345 137.430 91.656  1.00 69.49  ? 184 ARG R NH2 1 
ATOM 1188 N N   . ARG A 1 241 ? 112.800 144.292 89.620  1.00 69.49  ? 185 ARG R N   1 
ATOM 1189 C CA  . ARG A 1 241 ? 111.458 144.696 89.236  1.00 69.49  ? 185 ARG R CA  1 
ATOM 1190 C C   . ARG A 1 241 ? 110.888 143.660 88.279  1.00 69.49  ? 185 ARG R C   1 
ATOM 1191 O O   . ARG A 1 241 ? 111.591 142.761 87.808  1.00 69.49  ? 185 ARG R O   1 
ATOM 1192 C CB  . ARG A 1 241 ? 111.451 146.085 88.586  1.00 69.49  ? 185 ARG R CB  1 
ATOM 1193 C CG  . ARG A 1 241 ? 111.987 146.109 87.165  1.00 69.49  ? 185 ARG R CG  1 
ATOM 1194 C CD  . ARG A 1 241 ? 111.793 147.456 86.509  1.00 69.49  ? 185 ARG R CD  1 
ATOM 1195 N NE  . ARG A 1 241 ? 112.410 147.493 85.187  1.00 69.49  ? 185 ARG R NE  1 
ATOM 1196 C CZ  . ARG A 1 241 ? 111.762 147.679 84.045  1.00 69.49  ? 185 ARG R CZ  1 
ATOM 1197 N NH1 . ARG A 1 241 ? 110.449 147.840 84.006  1.00 69.49  ? 185 ARG R NH1 1 
ATOM 1198 N NH2 . ARG A 1 241 ? 112.449 147.702 82.907  1.00 69.49  ? 185 ARG R NH2 1 
ATOM 1199 N N   . THR A 1 242 ? 109.600 143.804 87.979  1.00 69.49  ? 186 THR R N   1 
ATOM 1200 C CA  . THR A 1 242 ? 108.938 142.955 86.996  1.00 69.49  ? 186 THR R CA  1 
ATOM 1201 C C   . THR A 1 242 ? 109.194 143.526 85.609  1.00 69.49  ? 186 THR R C   1 
ATOM 1202 O O   . THR A 1 242 ? 108.644 144.571 85.249  1.00 69.49  ? 186 THR R O   1 
ATOM 1203 C CB  . THR A 1 242 ? 107.443 142.870 87.273  1.00 69.49  ? 186 THR R CB  1 
ATOM 1204 O OG1 . THR A 1 242 ? 106.828 144.122 86.953  1.00 69.49  ? 186 THR R OG1 1 
ATOM 1205 C CG2 . THR A 1 242 ? 107.193 142.551 88.728  1.00 69.49  ? 186 THR R CG2 1 
ATOM 1206 N N   . VAL A 1 243 ? 110.020 142.841 84.830  1.00 69.49  ? 187 VAL R N   1 
ATOM 1207 C CA  . VAL A 1 243 ? 110.385 143.259 83.484  1.00 69.49  ? 187 VAL R CA  1 
ATOM 1208 C C   . VAL A 1 243 ? 109.446 142.554 82.517  1.00 69.49  ? 187 VAL R C   1 
ATOM 1209 O O   . VAL A 1 243 ? 109.290 141.328 82.571  1.00 69.49  ? 187 VAL R O   1 
ATOM 1210 C CB  . VAL A 1 243 ? 111.851 142.935 83.176  1.00 69.49  ? 187 VAL R CB  1 
ATOM 1211 C CG1 . VAL A 1 243 ? 112.209 143.380 81.774  1.00 69.49  ? 187 VAL R CG1 1 
ATOM 1212 C CG2 . VAL A 1 243 ? 112.762 143.590 84.194  1.00 69.49  ? 187 VAL R CG2 1 
ATOM 1213 N N   . TYR A 1 244 ? 108.814 143.330 81.640  1.00 69.49  ? 188 TYR R N   1 
ATOM 1214 C CA  . TYR A 1 244 ? 107.915 142.810 80.618  1.00 69.49  ? 188 TYR R CA  1 
ATOM 1215 C C   . TYR A 1 244 ? 108.644 142.797 79.282  1.00 69.49  ? 188 TYR R C   1 
ATOM 1216 O O   . TYR A 1 244 ? 109.169 143.827 78.849  1.00 69.49  ? 188 TYR R O   1 
ATOM 1217 C CB  . TYR A 1 244 ? 106.643 143.652 80.513  1.00 69.49  ? 188 TYR R CB  1 
ATOM 1218 C CG  . TYR A 1 244 ? 105.826 143.733 81.779  1.00 69.49  ? 188 TYR R CG  1 
ATOM 1219 C CD1 . TYR A 1 244 ? 106.238 144.511 82.847  1.00 69.49  ? 188 TYR R CD1 1 
ATOM 1220 C CD2 . TYR A 1 244 ? 104.632 143.042 81.897  1.00 69.49  ? 188 TYR R CD2 1 
ATOM 1221 C CE1 . TYR A 1 244 ? 105.489 144.589 84.001  1.00 69.49  ? 188 TYR R CE1 1 
ATOM 1222 C CE2 . TYR A 1 244 ? 103.876 143.113 83.046  1.00 69.49  ? 188 TYR R CE2 1 
ATOM 1223 C CZ  . TYR A 1 244 ? 104.309 143.888 84.095  1.00 69.49  ? 188 TYR R CZ  1 
ATOM 1224 O OH  . TYR A 1 244 ? 103.560 143.965 85.245  1.00 69.49  ? 188 TYR R OH  1 
ATOM 1225 N N   . SER A 1 245 ? 108.670 141.641 78.635  1.00 77.98  ? 189 SER R N   1 
ATOM 1226 C CA  . SER A 1 245 ? 109.288 141.483 77.332  1.00 77.98  ? 189 SER R CA  1 
ATOM 1227 C C   . SER A 1 245 ? 108.200 141.436 76.256  1.00 77.98  ? 189 SER R C   1 
ATOM 1228 O O   . SER A 1 245 ? 107.015 141.633 76.544  1.00 77.98  ? 189 SER R O   1 
ATOM 1229 C CB  . SER A 1 245 ? 110.161 140.224 77.338  1.00 77.98  ? 189 SER R CB  1 
ATOM 1230 O OG  . SER A 1 245 ? 111.246 140.364 78.236  1.00 77.98  ? 189 SER R OG  1 
ATOM 1231 N N   . SER A 1 246 ? 108.598 141.180 75.009  1.00 85.97  ? 190 SER R N   1 
ATOM 1232 C CA  . SER A 1 246 ? 107.661 141.033 73.906  1.00 85.97  ? 190 SER R CA  1 
ATOM 1233 C C   . SER A 1 246 ? 107.539 139.606 73.398  1.00 85.97  ? 190 SER R C   1 
ATOM 1234 O O   . SER A 1 246 ? 106.533 139.286 72.756  1.00 85.97  ? 190 SER R O   1 
ATOM 1235 C CB  . SER A 1 246 ? 108.069 141.938 72.733  1.00 85.97  ? 190 SER R CB  1 
ATOM 1236 O OG  . SER A 1 246 ? 109.231 141.447 72.089  1.00 85.97  ? 190 SER R OG  1 
ATOM 1237 N N   . ASN A 1 247 ? 108.526 138.749 73.658  1.00 89.77  ? 191 ASN R N   1 
ATOM 1238 C CA  . ASN A 1 247 ? 108.467 137.344 73.289  1.00 89.77  ? 191 ASN R CA  1 
ATOM 1239 C C   . ASN A 1 247 ? 108.485 136.411 74.490  1.00 89.77  ? 191 ASN R C   1 
ATOM 1240 O O   . ASN A 1 247 ? 108.357 135.197 74.309  1.00 89.77  ? 191 ASN R O   1 
ATOM 1241 C CB  . ASN A 1 247 ? 109.637 136.993 72.359  1.00 89.77  ? 191 ASN R CB  1 
ATOM 1242 C CG  . ASN A 1 247 ? 110.974 137.451 72.906  1.00 89.77  ? 191 ASN R CG  1 
ATOM 1243 O OD1 . ASN A 1 247 ? 111.062 137.941 74.030  1.00 89.77  ? 191 ASN R OD1 1 
ATOM 1244 N ND2 . ASN A 1 247 ? 112.023 137.302 72.107  1.00 89.77  ? 191 ASN R ND2 1 
ATOM 1245 N N   . VAL A 1 248 ? 108.639 136.941 75.703  1.00 86.03  ? 192 VAL R N   1 
ATOM 1246 C CA  . VAL A 1 248 ? 108.697 136.144 76.918  1.00 86.03  ? 192 VAL R CA  1 
ATOM 1247 C C   . VAL A 1 248 ? 107.794 136.791 77.960  1.00 86.03  ? 192 VAL R C   1 
ATOM 1248 O O   . VAL A 1 248 ? 107.502 137.987 77.907  1.00 86.03  ? 192 VAL R O   1 
ATOM 1249 C CB  . VAL A 1 248 ? 110.143 136.010 77.444  1.00 86.03  ? 192 VAL R CB  1 
ATOM 1250 C CG1 . VAL A 1 248 ? 110.175 135.304 78.787  1.00 86.03  ? 192 VAL R CG1 1 
ATOM 1251 C CG2 . VAL A 1 248 ? 110.999 135.271 76.434  1.00 86.03  ? 192 VAL R CG2 1 
ATOM 1252 N N   . SER A 1 249 ? 107.346 135.980 78.910  1.00 76.92  ? 193 SER R N   1 
ATOM 1253 C CA  . SER A 1 249 ? 106.440 136.434 79.953  1.00 76.92  ? 193 SER R CA  1 
ATOM 1254 C C   . SER A 1 249 ? 107.176 137.302 80.964  1.00 76.92  ? 193 SER R C   1 
ATOM 1255 O O   . SER A 1 249 ? 108.404 137.275 81.052  1.00 76.92  ? 193 SER R O   1 
ATOM 1256 C CB  . SER A 1 249 ? 105.809 135.232 80.643  1.00 76.92  ? 193 SER R CB  1 
ATOM 1257 O OG  . SER A 1 249 ? 106.785 134.515 81.374  1.00 76.92  ? 193 SER R OG  1 
ATOM 1258 N N   . PRO A 1 250 ? 106.445 138.084 81.759  1.00 69.49  ? 194 PRO R N   1 
ATOM 1259 C CA  . PRO A 1 250 ? 107.100 138.969 82.728  1.00 69.49  ? 194 PRO R CA  1 
ATOM 1260 C C   . PRO A 1 250 ? 107.968 138.190 83.700  1.00 69.49  ? 194 PRO R C   1 
ATOM 1261 O O   . PRO A 1 250 ? 107.643 137.068 84.090  1.00 69.49  ? 194 PRO R O   1 
ATOM 1262 C CB  . PRO A 1 250 ? 105.924 139.638 83.444  1.00 69.49  ? 194 PRO R CB  1 
ATOM 1263 C CG  . PRO A 1 250 ? 104.801 139.541 82.479  1.00 69.49  ? 194 PRO R CG  1 
ATOM 1264 C CD  . PRO A 1 250 ? 104.982 138.222 81.810  1.00 69.49  ? 194 PRO R CD  1 
ATOM 1265 N N   . ALA A 1 251 ? 109.086 138.797 84.094  1.00 69.49  ? 195 ALA R N   1 
ATOM 1266 C CA  . ALA A 1 251 ? 110.037 138.130 84.971  1.00 69.49  ? 195 ALA R CA  1 
ATOM 1267 C C   . ALA A 1 251 ? 110.492 139.076 86.069  1.00 69.49  ? 195 ALA R C   1 
ATOM 1268 O O   . ALA A 1 251 ? 110.696 140.266 85.844  1.00 69.49  ? 195 ALA R O   1 
ATOM 1269 C CB  . ALA A 1 251 ? 111.254 137.624 84.191  1.00 69.49  ? 195 ALA R CB  1 
ATOM 1270 N N   . CYS A 1 252 ? 110.668 138.527 87.270  1.00 69.49  ? 196 CYS R N   1 
ATOM 1271 C CA  . CYS A 1 252 ? 111.203 139.285 88.400  1.00 69.49  ? 196 CYS R CA  1 
ATOM 1272 C C   . CYS A 1 252 ? 112.715 139.367 88.208  1.00 69.49  ? 196 CYS R C   1 
ATOM 1273 O O   . CYS A 1 252 ? 113.493 138.622 88.799  1.00 69.49  ? 196 CYS R O   1 
ATOM 1274 C CB  . CYS A 1 252 ? 110.810 138.626 89.721  1.00 69.49  ? 196 CYS R CB  1 
ATOM 1275 S SG  . CYS A 1 252 ? 111.719 139.160 91.194  1.00 69.49  ? 196 CYS R SG  1 
ATOM 1276 N N   . TYR A 1 253 ? 113.124 140.297 87.348  1.00 69.49  ? 197 TYR R N   1 
ATOM 1277 C CA  . TYR A 1 253 ? 114.499 140.436 86.896  1.00 69.49  ? 197 TYR R CA  1 
ATOM 1278 C C   . TYR A 1 253 ? 115.121 141.673 87.533  1.00 69.49  ? 197 TYR R C   1 
ATOM 1279 O O   . TYR A 1 253 ? 114.510 142.328 88.379  1.00 69.49  ? 197 TYR R O   1 
ATOM 1280 C CB  . TYR A 1 253 ? 114.535 140.507 85.368  1.00 69.49  ? 197 TYR R CB  1 
ATOM 1281 C CG  . TYR A 1 253 ? 115.846 140.087 84.748  1.00 69.49  ? 197 TYR R CG  1 
ATOM 1282 C CD1 . TYR A 1 253 ? 116.312 138.790 84.873  1.00 69.49  ? 197 TYR R CD1 1 
ATOM 1283 C CD2 . TYR A 1 253 ? 116.614 140.991 84.035  1.00 69.49  ? 197 TYR R CD2 1 
ATOM 1284 C CE1 . TYR A 1 253 ? 117.506 138.408 84.306  1.00 69.49  ? 197 TYR R CE1 1 
ATOM 1285 C CE2 . TYR A 1 253 ? 117.807 140.619 83.467  1.00 69.49  ? 197 TYR R CE2 1 
ATOM 1286 C CZ  . TYR A 1 253 ? 118.249 139.327 83.604  1.00 69.49  ? 197 TYR R CZ  1 
ATOM 1287 O OH  . TYR A 1 253 ? 119.443 138.954 83.035  1.00 69.49  ? 197 TYR R OH  1 
ATOM 1288 N N   . GLU A 1 254 ? 116.348 141.990 87.130  1.00 69.49  ? 198 GLU R N   1 
ATOM 1289 C CA  . GLU A 1 254 ? 117.053 143.168 87.611  1.00 69.49  ? 198 GLU R CA  1 
ATOM 1290 C C   . GLU A 1 254 ? 116.937 144.310 86.611  1.00 69.49  ? 198 GLU R C   1 
ATOM 1291 O O   . GLU A 1 254 ? 116.715 144.093 85.418  1.00 69.49  ? 198 GLU R O   1 
ATOM 1292 C CB  . GLU A 1 254 ? 118.532 142.869 87.868  1.00 69.49  ? 198 GLU R CB  1 
ATOM 1293 C CG  . GLU A 1 254 ? 118.798 142.011 89.090  1.00 69.49  ? 198 GLU R CG  1 
ATOM 1294 C CD  . GLU A 1 254 ? 118.805 140.529 88.784  1.00 69.49  ? 198 GLU R CD  1 
ATOM 1295 O OE1 . GLU A 1 254 ? 118.518 140.151 87.630  1.00 69.49  ? 198 GLU R OE1 1 
ATOM 1296 O OE2 . GLU A 1 254 ? 119.101 139.736 89.702  1.00 69.49  ? 198 GLU R OE2 1 
ATOM 1297 N N   . ASP A 1 255 ? 117.085 145.537 87.114  1.00 57.33  ? 199 ASP R N   1 
ATOM 1298 C CA  . ASP A 1 255 ? 117.035 146.753 86.297  1.00 57.33  ? 199 ASP R CA  1 
ATOM 1299 C C   . ASP A 1 255 ? 118.099 147.713 86.829  1.00 57.33  ? 199 ASP R C   1 
ATOM 1300 O O   . ASP A 1 255 ? 117.835 148.511 87.728  1.00 57.33  ? 199 ASP R O   1 
ATOM 1301 C CB  . ASP A 1 255 ? 115.645 147.372 86.334  1.00 57.33  ? 199 ASP R CB  1 
ATOM 1302 C CG  . ASP A 1 255 ? 115.483 148.503 85.340  1.00 57.33  ? 199 ASP R CG  1 
ATOM 1303 O OD1 . ASP A 1 255 ? 116.329 149.417 85.332  1.00 57.33  ? 199 ASP R OD1 1 
ATOM 1304 O OD2 . ASP A 1 255 ? 114.503 148.482 84.569  1.00 57.33  ? 199 ASP R OD2 1 
ATOM 1305 N N   . MET A 1 256 ? 119.303 147.638 86.266  1.00 58.77  ? 200 MET R N   1 
ATOM 1306 C CA  . MET A 1 256 ? 120.424 148.452 86.712  1.00 58.77  ? 200 MET R CA  1 
ATOM 1307 C C   . MET A 1 256 ? 120.834 149.505 85.692  1.00 58.77  ? 200 MET R C   1 
ATOM 1308 O O   . MET A 1 256 ? 121.944 150.036 85.783  1.00 58.77  ? 200 MET R O   1 
ATOM 1309 C CB  . MET A 1 256 ? 121.624 147.564 87.035  1.00 58.77  ? 200 MET R CB  1 
ATOM 1310 C CG  . MET A 1 256 ? 121.376 146.578 88.146  1.00 58.77  ? 200 MET R CG  1 
ATOM 1311 S SD  . MET A 1 256 ? 122.752 145.447 88.363  1.00 58.77  ? 200 MET R SD  1 
ATOM 1312 C CE  . MET A 1 256 ? 121.881 143.968 88.857  1.00 58.77  ? 200 MET R CE  1 
ATOM 1313 N N   . GLY A 1 257 ? 119.984 149.812 84.725  1.00 53.94  ? 201 GLY R N   1 
ATOM 1314 C CA  . GLY A 1 257 ? 120.268 150.829 83.735  1.00 53.94  ? 201 GLY R CA  1 
ATOM 1315 C C   . GLY A 1 257 ? 120.676 150.221 82.410  1.00 53.94  ? 201 GLY R C   1 
ATOM 1316 O O   . GLY A 1 257 ? 120.509 149.024 82.161  1.00 53.94  ? 201 GLY R O   1 
ATOM 1317 N N   . ASN A 1 258 ? 121.241 151.070 81.550  1.00 62.34  ? 202 ASN R N   1 
ATOM 1318 C CA  . ASN A 1 258 ? 121.551 150.647 80.189  1.00 62.34  ? 202 ASN R CA  1 
ATOM 1319 C C   . ASN A 1 258 ? 122.528 149.480 80.162  1.00 62.34  ? 202 ASN R C   1 
ATOM 1320 O O   . ASN A 1 258 ? 122.493 148.670 79.232  1.00 62.34  ? 202 ASN R O   1 
ATOM 1321 C CB  . ASN A 1 258 ? 122.116 151.819 79.391  1.00 62.34  ? 202 ASN R CB  1 
ATOM 1322 C CG  . ASN A 1 258 ? 121.126 152.955 79.241  1.00 62.34  ? 202 ASN R CG  1 
ATOM 1323 O OD1 . ASN A 1 258 ? 121.405 154.090 79.623  1.00 62.34  ? 202 ASN R OD1 1 
ATOM 1324 N ND2 . ASN A 1 258 ? 119.959 152.655 78.687  1.00 62.34  ? 202 ASN R ND2 1 
ATOM 1325 N N   . ASN A 1 259 ? 123.405 149.375 81.159  1.00 66.24  ? 203 ASN R N   1 
ATOM 1326 C CA  . ASN A 1 259 ? 124.411 148.321 81.213  1.00 66.24  ? 203 ASN R CA  1 
ATOM 1327 C C   . ASN A 1 259 ? 124.035 147.230 82.208  1.00 66.24  ? 203 ASN R C   1 
ATOM 1328 O O   . ASN A 1 259 ? 124.897 146.690 82.903  1.00 66.24  ? 203 ASN R O   1 
ATOM 1329 C CB  . ASN A 1 259 ? 125.778 148.905 81.561  1.00 66.24  ? 203 ASN R CB  1 
ATOM 1330 C CG  . ASN A 1 259 ? 126.362 149.727 80.434  1.00 66.24  ? 203 ASN R CG  1 
ATOM 1331 O OD1 . ASN A 1 259 ? 126.012 149.542 79.270  1.00 66.24  ? 203 ASN R OD1 1 
ATOM 1332 N ND2 . ASN A 1 259 ? 127.260 150.642 80.774  1.00 66.24  ? 203 ASN R ND2 1 
ATOM 1333 N N   . THR A 1 260 ? 122.748 146.895 82.286  1.00 62.15  ? 204 THR R N   1 
ATOM 1334 C CA  . THR A 1 260 ? 122.301 145.916 83.268  1.00 62.15  ? 204 THR R CA  1 
ATOM 1335 C C   . THR A 1 260 ? 122.944 144.555 83.040  1.00 62.15  ? 204 THR R C   1 
ATOM 1336 O O   . THR A 1 260 ? 123.163 143.802 83.991  1.00 62.15  ? 204 THR R O   1 
ATOM 1337 C CB  . THR A 1 260 ? 120.781 145.791 83.226  1.00 62.15  ? 204 THR R CB  1 
ATOM 1338 O OG1 . THR A 1 260 ? 120.190 147.070 83.477  1.00 62.15  ? 204 THR R OG1 1 
ATOM 1339 C CG2 . THR A 1 260 ? 120.301 144.801 84.266  1.00 62.15  ? 204 THR R CG2 1 
ATOM 1340 N N   . ALA A 1 261 ? 123.245 144.215 81.788  1.00 64.58  ? 205 ALA R N   1 
ATOM 1341 C CA  . ALA A 1 261 ? 123.819 142.903 81.504  1.00 64.58  ? 205 ALA R CA  1 
ATOM 1342 C C   . ALA A 1 261 ? 125.182 142.740 82.169  1.00 64.58  ? 205 ALA R C   1 
ATOM 1343 O O   . ALA A 1 261 ? 125.428 141.761 82.887  1.00 64.58  ? 205 ALA R O   1 
ATOM 1344 C CB  . ALA A 1 261 ? 123.930 142.702 79.995  1.00 64.58  ? 205 ALA R CB  1 
ATOM 1345 N N   . ASN A 1 262 ? 126.083 143.696 81.943  1.00 67.65  ? 206 ASN R N   1 
ATOM 1346 C CA  . ASN A 1 262 ? 127.425 143.594 82.506  1.00 67.65  ? 206 ASN R CA  1 
ATOM 1347 C C   . ASN A 1 262 ? 127.399 143.700 84.026  1.00 67.65  ? 206 ASN R C   1 
ATOM 1348 O O   . ASN A 1 262 ? 128.122 142.972 84.719  1.00 67.65  ? 206 ASN R O   1 
ATOM 1349 C CB  . ASN A 1 262 ? 128.317 144.676 81.905  1.00 67.65  ? 206 ASN R CB  1 
ATOM 1350 C CG  . ASN A 1 262 ? 128.223 144.730 80.396  1.00 67.65  ? 206 ASN R CG  1 
ATOM 1351 O OD1 . ASN A 1 262 ? 127.383 144.065 79.793  1.00 67.65  ? 206 ASN R OD1 1 
ATOM 1352 N ND2 . ASN A 1 262 ? 129.086 145.525 79.776  1.00 67.65  ? 206 ASN R ND2 1 
ATOM 1353 N N   . TRP A 1 263 ? 126.580 144.603 84.567  1.00 65.46  ? 207 TRP R N   1 
ATOM 1354 C CA  . TRP A 1 263 ? 126.486 144.713 86.017  1.00 65.46  ? 207 TRP R CA  1 
ATOM 1355 C C   . TRP A 1 263 ? 125.951 143.424 86.618  1.00 65.46  ? 207 TRP R C   1 
ATOM 1356 O O   . TRP A 1 263 ? 126.379 143.012 87.698  1.00 65.46  ? 207 TRP R O   1 
ATOM 1357 C CB  . TRP A 1 263 ? 125.594 145.887 86.416  1.00 65.46  ? 207 TRP R CB  1 
ATOM 1358 C CG  . TRP A 1 263 ? 126.096 147.244 86.007  1.00 65.46  ? 207 TRP R CG  1 
ATOM 1359 C CD1 . TRP A 1 263 ? 125.338 148.287 85.569  1.00 65.46  ? 207 TRP R CD1 1 
ATOM 1360 C CD2 . TRP A 1 263 ? 127.455 147.705 85.991  1.00 65.46  ? 207 TRP R CD2 1 
ATOM 1361 N NE1 . TRP A 1 263 ? 126.133 149.367 85.286  1.00 65.46  ? 207 TRP R NE1 1 
ATOM 1362 C CE2 . TRP A 1 263 ? 127.437 149.035 85.534  1.00 65.46  ? 207 TRP R CE2 1 
ATOM 1363 C CE3 . TRP A 1 263 ? 128.683 147.124 86.317  1.00 65.46  ? 207 TRP R CE3 1 
ATOM 1364 C CZ2 . TRP A 1 263 ? 128.595 149.791 85.395  1.00 65.46  ? 207 TRP R CZ2 1 
ATOM 1365 C CZ3 . TRP A 1 263 ? 129.830 147.876 86.178  1.00 65.46  ? 207 TRP R CZ3 1 
ATOM 1366 C CH2 . TRP A 1 263 ? 129.779 149.195 85.721  1.00 65.46  ? 207 TRP R CH2 1 
ATOM 1367 N N   . ARG A 1 264 ? 125.004 142.781 85.939  1.00 69.49  ? 208 ARG R N   1 
ATOM 1368 C CA  . ARG A 1 264 ? 124.487 141.508 86.422  1.00 69.49  ? 208 ARG R CA  1 
ATOM 1369 C C   . ARG A 1 264 ? 125.573 140.442 86.404  1.00 69.49  ? 208 ARG R C   1 
ATOM 1370 O O   . ARG A 1 264 ? 125.695 139.648 87.345  1.00 69.49  ? 208 ARG R O   1 
ATOM 1371 C CB  . ARG A 1 264 ? 123.295 141.083 85.570  1.00 64.69  ? 208 ARG R CB  1 
ATOM 1372 C CG  . ARG A 1 264 ? 122.477 139.973 86.175  1.00 64.69  ? 208 ARG R CG  1 
ATOM 1373 C CD  . ARG A 1 264 ? 121.051 140.006 85.669  1.00 64.69  ? 208 ARG R CD  1 
ATOM 1374 N NE  . ARG A 1 264 ? 120.344 138.775 85.992  1.00 64.69  ? 208 ARG R NE  1 
ATOM 1375 C CZ  . ARG A 1 264 ? 120.597 137.597 85.442  1.00 64.69  ? 208 ARG R CZ  1 
ATOM 1376 N NH1 . ARG A 1 264 ? 121.514 137.456 84.500  1.00 64.69  ? 208 ARG R NH1 1 
ATOM 1377 N NH2 . ARG A 1 264 ? 119.911 136.533 85.847  1.00 64.69  ? 208 ARG R NH2 1 
ATOM 1378 N N   . MET A 1 265 ? 126.380 140.419 85.345  1.00 70.28  ? 209 MET R N   1 
ATOM 1379 C CA  . MET A 1 265 ? 127.480 139.462 85.293  1.00 70.28  ? 209 MET R CA  1 
ATOM 1380 C C   . MET A 1 265 ? 128.453 139.685 86.443  1.00 70.28  ? 209 MET R C   1 
ATOM 1381 O O   . MET A 1 265 ? 128.953 138.723 87.034  1.00 70.28  ? 209 MET R O   1 
ATOM 1382 C CB  . MET A 1 265 ? 128.200 139.561 83.952  1.00 70.28  ? 209 MET R CB  1 
ATOM 1383 C CG  . MET A 1 265 ? 127.379 139.053 82.787  1.00 70.28  ? 209 MET R CG  1 
ATOM 1384 S SD  . MET A 1 265 ? 128.146 139.403 81.198  1.00 70.28  ? 209 MET R SD  1 
ATOM 1385 C CE  . MET A 1 265 ? 129.314 138.056 81.098  1.00 70.28  ? 209 MET R CE  1 
ATOM 1386 N N   . LEU A 1 266 ? 128.747 140.946 86.767  1.00 69.49  ? 210 LEU R N   1 
ATOM 1387 C CA  . LEU A 1 266 ? 129.631 141.220 87.898  1.00 69.49  ? 210 LEU R CA  1 
ATOM 1388 C C   . LEU A 1 266 ? 128.988 140.815 89.220  1.00 69.49  ? 210 LEU R C   1 
ATOM 1389 O O   . LEU A 1 266 ? 129.638 140.194 90.067  1.00 69.49  ? 210 LEU R O   1 
ATOM 1390 C CB  . LEU A 1 266 ? 130.021 142.697 87.930  1.00 69.49  ? 210 LEU R CB  1 
ATOM 1391 C CG  . LEU A 1 266 ? 130.934 143.194 86.810  1.00 69.49  ? 210 LEU R CG  1 
ATOM 1392 C CD1 . LEU A 1 266 ? 131.305 144.643 87.045  1.00 69.49  ? 210 LEU R CD1 1 
ATOM 1393 C CD2 . LEU A 1 266 ? 132.183 142.338 86.704  1.00 69.49  ? 210 LEU R CD2 1 
ATOM 1394 N N   . LEU A 1 267 ? 127.714 141.158 89.418  1.00 69.49  ? 211 LEU R N   1 
ATOM 1395 C CA  . LEU A 1 267 ? 127.018 140.766 90.636  1.00 69.49  ? 211 LEU R CA  1 
ATOM 1396 C C   . LEU A 1 267 ? 126.956 139.257 90.788  1.00 69.49  ? 211 LEU R C   1 
ATOM 1397 O O   . LEU A 1 267 ? 126.779 138.764 91.906  1.00 69.49  ? 211 LEU R O   1 
ATOM 1398 C CB  . LEU A 1 267 ? 125.595 141.327 90.649  1.00 69.49  ? 211 LEU R CB  1 
ATOM 1399 C CG  . LEU A 1 267 ? 125.382 142.836 90.773  1.00 69.49  ? 211 LEU R CG  1 
ATOM 1400 C CD1 . LEU A 1 267 ? 124.031 143.097 91.404  1.00 69.49  ? 211 LEU R CD1 1 
ATOM 1401 C CD2 . LEU A 1 267 ? 126.485 143.508 91.574  1.00 69.49  ? 211 LEU R CD2 1 
ATOM 1402 N N   . ARG A 1 268 ? 127.070 138.515 89.687  1.00 69.49  ? 212 ARG R N   1 
ATOM 1403 C CA  . ARG A 1 268 ? 127.119 137.062 89.785  1.00 69.49  ? 212 ARG R CA  1 
ATOM 1404 C C   . ARG A 1 268 ? 128.363 136.573 90.515  1.00 69.49  ? 212 ARG R C   1 
ATOM 1405 O O   . ARG A 1 268 ? 128.408 135.408 90.919  1.00 69.49  ? 212 ARG R O   1 
ATOM 1406 C CB  . ARG A 1 268 ? 127.061 136.435 88.393  1.00 69.49  ? 212 ARG R CB  1 
ATOM 1407 C CG  . ARG A 1 268 ? 125.720 135.811 88.062  1.00 69.49  ? 212 ARG R CG  1 
ATOM 1408 C CD  . ARG A 1 268 ? 125.847 134.746 86.998  1.00 69.49  ? 212 ARG R CD  1 
ATOM 1409 N NE  . ARG A 1 268 ? 126.100 135.306 85.676  1.00 69.49  ? 212 ARG R NE  1 
ATOM 1410 C CZ  . ARG A 1 268 ? 125.311 135.153 84.621  1.00 69.49  ? 212 ARG R CZ  1 
ATOM 1411 N NH1 . ARG A 1 268 ? 124.183 134.466 84.688  1.00 69.49  ? 212 ARG R NH1 1 
ATOM 1412 N NH2 . ARG A 1 268 ? 125.661 135.708 83.465  1.00 69.49  ? 212 ARG R NH2 1 
ATOM 1413 N N   . ILE A 1 269 ? 129.371 137.428 90.693  1.00 69.49  ? 213 ILE R N   1 
ATOM 1414 C CA  . ILE A 1 269 ? 130.590 137.004 91.374  1.00 69.49  ? 213 ILE R CA  1 
ATOM 1415 C C   . ILE A 1 269 ? 130.310 136.710 92.842  1.00 69.49  ? 213 ILE R C   1 
ATOM 1416 O O   . ILE A 1 269 ? 130.901 135.796 93.428  1.00 69.49  ? 213 ILE R O   1 
ATOM 1417 C CB  . ILE A 1 269 ? 131.691 138.067 91.200  1.00 69.49  ? 213 ILE R CB  1 
ATOM 1418 C CG1 . ILE A 1 269 ? 133.069 137.408 91.162  1.00 69.49  ? 213 ILE R CG1 1 
ATOM 1419 C CG2 . ILE A 1 269 ? 131.642 139.097 92.318  1.00 69.49  ? 213 ILE R CG2 1 
ATOM 1420 C CD1 . ILE A 1 269 ? 134.185 138.362 90.803  1.00 69.49  ? 213 ILE R CD1 1 
ATOM 1421 N N   . LEU A 1 270 ? 129.417 137.480 93.466  1.00 69.49  ? 214 LEU R N   1 
ATOM 1422 C CA  . LEU A 1 270 ? 129.119 137.269 94.881  1.00 69.49  ? 214 LEU R CA  1 
ATOM 1423 C C   . LEU A 1 270 ? 128.534 135.889 95.150  1.00 69.49  ? 214 LEU R C   1 
ATOM 1424 O O   . LEU A 1 270 ? 129.075 135.162 96.000  1.00 69.49  ? 214 LEU R O   1 
ATOM 1425 C CB  . LEU A 1 270 ? 128.189 138.382 95.372  1.00 69.49  ? 214 LEU R CB  1 
ATOM 1426 C CG  . LEU A 1 270 ? 128.781 139.789 95.419  1.00 69.49  ? 214 LEU R CG  1 
ATOM 1427 C CD1 . LEU A 1 270 ? 127.686 140.802 95.662  1.00 69.49  ? 214 LEU R CD1 1 
ATOM 1428 C CD2 . LEU A 1 270 ? 129.842 139.891 96.496  1.00 69.49  ? 214 LEU R CD2 1 
ATOM 1429 N N   . PRO A 1 271 ? 127.454 135.464 94.489  1.00 69.49  ? 215 PRO R N   1 
ATOM 1430 C CA  . PRO A 1 271 ? 126.922 134.121 94.770  1.00 69.49  ? 215 PRO R CA  1 
ATOM 1431 C C   . PRO A 1 271 ? 127.874 132.998 94.408  1.00 69.49  ? 215 PRO R C   1 
ATOM 1432 O O   . PRO A 1 271 ? 127.723 131.888 94.930  1.00 69.49  ? 215 PRO R O   1 
ATOM 1433 C CB  . PRO A 1 271 ? 125.637 134.062 93.930  1.00 69.49  ? 215 PRO R CB  1 
ATOM 1434 C CG  . PRO A 1 271 ? 125.732 135.173 92.961  1.00 69.49  ? 215 PRO R CG  1 
ATOM 1435 C CD  . PRO A 1 271 ? 126.583 136.222 93.579  1.00 69.49  ? 215 PRO R CD  1 
ATOM 1436 N N   . GLN A 1 272 ? 128.840 133.236 93.526  1.00 69.49  ? 216 GLN R N   1 
ATOM 1437 C CA  . GLN A 1 272 ? 129.770 132.199 93.103  1.00 69.49  ? 216 GLN R CA  1 
ATOM 1438 C C   . GLN A 1 272 ? 131.052 132.165 93.923  1.00 69.49  ? 216 GLN R C   1 
ATOM 1439 O O   . GLN A 1 272 ? 131.808 131.197 93.812  1.00 69.49  ? 216 GLN R O   1 
ATOM 1440 C CB  . GLN A 1 272 ? 130.125 132.374 91.625  1.00 69.49  ? 216 GLN R CB  1 
ATOM 1441 C CG  . GLN A 1 272 ? 128.961 132.184 90.680  1.00 69.49  ? 216 GLN R CG  1 
ATOM 1442 C CD  . GLN A 1 272 ? 129.406 131.745 89.304  1.00 69.49  ? 216 GLN R CD  1 
ATOM 1443 O OE1 . GLN A 1 272 ? 129.672 132.570 88.431  1.00 69.49  ? 216 GLN R OE1 1 
ATOM 1444 N NE2 . GLN A 1 272 ? 129.494 130.438 89.102  1.00 69.49  ? 216 GLN R NE2 1 
ATOM 1445 N N   . SER A 1 273 ? 131.320 133.184 94.735  1.00 69.49  ? 217 SER R N   1 
ATOM 1446 C CA  . SER A 1 273 ? 132.506 133.217 95.581  1.00 69.49  ? 217 SER R CA  1 
ATOM 1447 C C   . SER A 1 273 ? 132.167 133.074 97.055  1.00 69.49  ? 217 SER R C   1 
ATOM 1448 O O   . SER A 1 273 ? 132.772 132.256 97.751  1.00 69.49  ? 217 SER R O   1 
ATOM 1449 C CB  . SER A 1 273 ? 133.285 134.517 95.353  1.00 69.49  ? 217 SER R CB  1 
ATOM 1450 O OG  . SER A 1 273 ? 132.490 135.644 95.667  1.00 69.49  ? 217 SER R OG  1 
ATOM 1451 N N   . PHE A 1 274 ? 131.212 133.851 97.552  1.00 69.49  ? 218 PHE R N   1 
ATOM 1452 C CA  . PHE A 1 274 ? 130.714 133.694 98.910  1.00 69.49  ? 218 PHE R CA  1 
ATOM 1453 C C   . PHE A 1 274 ? 129.606 132.661 99.001  1.00 69.49  ? 218 PHE R C   1 
ATOM 1454 O O   . PHE A 1 274 ? 129.083 132.427 100.094 1.00 69.49  ? 218 PHE R O   1 
ATOM 1455 C CB  . PHE A 1 274 ? 130.205 135.032 99.449  1.00 69.49  ? 218 PHE R CB  1 
ATOM 1456 C CG  . PHE A 1 274 ? 131.294 136.000 99.790  1.00 69.49  ? 218 PHE R CG  1 
ATOM 1457 C CD1 . PHE A 1 274 ? 131.998 136.650 98.794  1.00 69.49  ? 218 PHE R CD1 1 
ATOM 1458 C CD2 . PHE A 1 274 ? 131.616 136.261 101.108 1.00 69.49  ? 218 PHE R CD2 1 
ATOM 1459 C CE1 . PHE A 1 274 ? 133.000 137.542 99.106  1.00 69.49  ? 218 PHE R CE1 1 
ATOM 1460 C CE2 . PHE A 1 274 ? 132.617 137.152 101.426 1.00 69.49  ? 218 PHE R CE2 1 
ATOM 1461 C CZ  . PHE A 1 274 ? 133.310 137.794 100.424 1.00 69.49  ? 218 PHE R CZ  1 
ATOM 1462 N N   . GLY A 1 275 ? 129.233 132.043 97.886  1.00 69.49  ? 219 GLY R N   1 
ATOM 1463 C CA  . GLY A 1 275 ? 128.143 131.092 97.881  1.00 69.49  ? 219 GLY R CA  1 
ATOM 1464 C C   . GLY A 1 275 ? 128.567 129.704 97.454  1.00 69.49  ? 219 GLY R C   1 
ATOM 1465 O O   . GLY A 1 275 ? 127.936 128.720 97.848  1.00 69.49  ? 219 GLY R O   1 
ATOM 1466 N N   . PHE A 1 276 ? 129.605 129.604 96.625  1.00 53.02  ? 220 PHE R N   1 
ATOM 1467 C CA  . PHE A 1 276 ? 130.129 128.294 96.262  1.00 53.02  ? 220 PHE R CA  1 
ATOM 1468 C C   . PHE A 1 276 ? 131.594 128.108 96.641  1.00 53.02  ? 220 PHE R C   1 
ATOM 1469 O O   . PHE A 1 276 ? 131.935 127.161 97.354  1.00 53.02  ? 220 PHE R O   1 
ATOM 1470 C CB  . PHE A 1 276 ? 129.956 128.056 94.762  1.00 53.02  ? 220 PHE R CB  1 
ATOM 1471 C CG  . PHE A 1 276 ? 130.319 126.667 94.331  1.00 53.02  ? 220 PHE R CG  1 
ATOM 1472 C CD1 . PHE A 1 276 ? 129.691 125.570 94.890  1.00 53.02  ? 220 PHE R CD1 1 
ATOM 1473 C CD2 . PHE A 1 276 ? 131.291 126.459 93.372  1.00 53.02  ? 220 PHE R CD2 1 
ATOM 1474 C CE1 . PHE A 1 276 ? 130.025 124.295 94.501  1.00 53.02  ? 220 PHE R CE1 1 
ATOM 1475 C CE2 . PHE A 1 276 ? 131.628 125.185 92.978  1.00 53.02  ? 220 PHE R CE2 1 
ATOM 1476 C CZ  . PHE A 1 276 ? 130.993 124.102 93.544  1.00 53.02  ? 220 PHE R CZ  1 
ATOM 1477 N N   . ILE A 1 277 ? 132.468 129.005 96.184  1.00 69.49  ? 221 ILE R N   1 
ATOM 1478 C CA  . ILE A 1 277 ? 133.900 128.717 96.216  1.00 69.49  ? 221 ILE R CA  1 
ATOM 1479 C C   . ILE A 1 277 ? 134.434 128.764 97.642  1.00 69.49  ? 221 ILE R C   1 
ATOM 1480 O O   . ILE A 1 277 ? 135.128 127.845 98.087  1.00 69.49  ? 221 ILE R O   1 
ATOM 1481 C CB  . ILE A 1 277 ? 134.666 129.683 95.298  1.00 50.42  ? 221 ILE R CB  1 
ATOM 1482 C CG1 . ILE A 1 277 ? 134.309 129.418 93.836  1.00 50.42  ? 221 ILE R CG1 1 
ATOM 1483 C CG2 . ILE A 1 277 ? 136.164 129.533 95.503  1.00 50.42  ? 221 ILE R CG2 1 
ATOM 1484 C CD1 . ILE A 1 277 ? 134.654 130.565 92.914  1.00 50.42  ? 221 ILE R CD1 1 
ATOM 1485 N N   . VAL A 1 278 ? 134.153 129.839 98.369  1.00 69.49  ? 222 VAL R N   1 
ATOM 1486 C CA  . VAL A 1 278 ? 134.716 130.004 99.707  1.00 69.49  ? 222 VAL R CA  1 
ATOM 1487 C C   . VAL A 1 278 ? 134.160 128.928 100.635 1.00 69.49  ? 222 VAL R C   1 
ATOM 1488 O O   . VAL A 1 278 ? 134.938 128.261 101.335 1.00 69.49  ? 222 VAL R O   1 
ATOM 1489 C CB  . VAL A 1 278 ? 134.453 131.417 100.251 1.00 45.25  ? 222 VAL R CB  1 
ATOM 1490 C CG1 . VAL A 1 278 ? 134.617 131.448 101.760 1.00 45.25  ? 222 VAL R CG1 1 
ATOM 1491 C CG2 . VAL A 1 278 ? 135.395 132.412 99.595  1.00 45.25  ? 222 VAL R CG2 1 
ATOM 1492 N N   . PRO A 1 279 ? 132.840 128.734 100.702 1.00 69.49  ? 223 PRO R N   1 
ATOM 1493 C CA  . PRO A 1 279 ? 132.321 127.627 101.519 1.00 69.49  ? 223 PRO R CA  1 
ATOM 1494 C C   . PRO A 1 279 ? 132.839 126.270 101.087 1.00 69.49  ? 223 PRO R C   1 
ATOM 1495 O O   . PRO A 1 279 ? 133.127 125.424 101.940 1.00 69.49  ? 223 PRO R O   1 
ATOM 1496 C CB  . PRO A 1 279 ? 130.802 127.740 101.338 1.00 45.53  ? 223 PRO R CB  1 
ATOM 1497 C CG  . PRO A 1 279 ? 130.566 129.134 100.932 1.00 45.53  ? 223 PRO R CG  1 
ATOM 1498 C CD  . PRO A 1 279 ? 131.753 129.547 100.136 1.00 45.53  ? 223 PRO R CD  1 
ATOM 1499 N N   . LEU A 1 280 ? 132.970 126.032 99.781  1.00 69.49  ? 224 LEU R N   1 
ATOM 1500 C CA  . LEU A 1 280 ? 133.471 124.743 99.322  1.00 69.49  ? 224 LEU R CA  1 
ATOM 1501 C C   . LEU A 1 280 ? 134.899 124.514 99.791  1.00 69.49  ? 224 LEU R C   1 
ATOM 1502 O O   . LEU A 1 280 ? 135.243 123.414 100.232 1.00 69.49  ? 224 LEU R O   1 
ATOM 1503 C CB  . LEU A 1 280 ? 133.395 124.656 97.799  1.00 44.50  ? 224 LEU R CB  1 
ATOM 1504 C CG  . LEU A 1 280 ? 133.848 123.327 97.188  1.00 44.50  ? 224 LEU R CG  1 
ATOM 1505 C CD1 . LEU A 1 280 ? 132.840 122.227 97.480  1.00 44.50  ? 224 LEU R CD1 1 
ATOM 1506 C CD2 . LEU A 1 280 ? 134.072 123.469 95.694  1.00 44.50  ? 224 LEU R CD2 1 
ATOM 1507 N N   . LEU A 1 281 ? 135.748 125.537 99.699  1.00 69.49  ? 225 LEU R N   1 
ATOM 1508 C CA  . LEU A 1 281 ? 137.132 125.387 100.135 1.00 69.49  ? 225 LEU R CA  1 
ATOM 1509 C C   . LEU A 1 281 ? 137.220 125.198 101.643 1.00 69.49  ? 225 LEU R C   1 
ATOM 1510 O O   . LEU A 1 281 ? 138.006 124.375 102.124 1.00 69.49  ? 225 LEU R O   1 
ATOM 1511 C CB  . LEU A 1 281 ? 137.954 126.597 99.697  1.00 69.49  ? 225 LEU R CB  1 
ATOM 1512 C CG  . LEU A 1 281 ? 138.251 126.727 98.202  1.00 69.49  ? 225 LEU R CG  1 
ATOM 1513 C CD1 . LEU A 1 281 ? 139.120 127.938 97.948  1.00 69.49  ? 225 LEU R CD1 1 
ATOM 1514 C CD2 . LEU A 1 281 ? 138.924 125.480 97.665  1.00 69.49  ? 225 LEU R CD2 1 
ATOM 1515 N N   . ILE A 1 282 ? 136.426 125.949 102.408 1.00 69.49  ? 226 ILE R N   1 
ATOM 1516 C CA  . ILE A 1 282 ? 136.436 125.774 103.859 1.00 69.49  ? 226 ILE R CA  1 
ATOM 1517 C C   . ILE A 1 282 ? 136.008 124.359 104.220 1.00 69.49  ? 226 ILE R C   1 
ATOM 1518 O O   . ILE A 1 282 ? 136.644 123.689 105.043 1.00 69.49  ? 226 ILE R O   1 
ATOM 1519 C CB  . ILE A 1 282 ? 135.536 126.822 104.537 1.00 35.57  ? 226 ILE R CB  1 
ATOM 1520 C CG1 . ILE A 1 282 ? 136.132 128.220 104.377 1.00 35.57  ? 226 ILE R CG1 1 
ATOM 1521 C CG2 . ILE A 1 282 ? 135.351 126.483 106.004 1.00 35.57  ? 226 ILE R CG2 1 
ATOM 1522 C CD1 . ILE A 1 282 ? 135.177 129.332 104.740 1.00 35.57  ? 226 ILE R CD1 1 
ATOM 1523 N N   . MET A 1 283 ? 134.923 123.882 103.609 1.00 69.49  ? 227 MET R N   1 
ATOM 1524 C CA  . MET A 1 283 ? 134.449 122.536 103.895 1.00 69.49  ? 227 MET R CA  1 
ATOM 1525 C C   . MET A 1 283 ? 135.484 121.496 103.501 1.00 69.49  ? 227 MET R C   1 
ATOM 1526 O O   . MET A 1 283 ? 135.735 120.549 104.250 1.00 69.49  ? 227 MET R O   1 
ATOM 1527 C CB  . MET A 1 283 ? 133.132 122.280 103.167 1.00 40.89  ? 227 MET R CB  1 
ATOM 1528 C CG  . MET A 1 283 ? 131.957 123.034 103.748 1.00 40.89  ? 227 MET R CG  1 
ATOM 1529 S SD  . MET A 1 283 ? 130.433 122.772 102.834 1.00 40.89  ? 227 MET R SD  1 
ATOM 1530 C CE  . MET A 1 283 ? 130.052 121.093 103.316 1.00 40.89  ? 227 MET R CE  1 
ATOM 1531 N N   . LEU A 1 284 ? 136.100 121.653 102.330 1.00 69.49  ? 228 LEU R N   1 
ATOM 1532 C CA  . LEU A 1 284 ? 137.095 120.684 101.894 1.00 69.49  ? 228 LEU R CA  1 
ATOM 1533 C C   . LEU A 1 284 ? 138.267 120.630 102.860 1.00 69.49  ? 228 LEU R C   1 
ATOM 1534 O O   . LEU A 1 284 ? 138.661 119.547 103.293 1.00 69.49  ? 228 LEU R O   1 
ATOM 1535 C CB  . LEU A 1 284 ? 137.577 121.024 100.487 1.00 35.80  ? 228 LEU R CB  1 
ATOM 1536 C CG  . LEU A 1 284 ? 136.612 120.701 99.347  1.00 35.80  ? 228 LEU R CG  1 
ATOM 1537 C CD1 . LEU A 1 284 ? 137.111 121.306 98.051  1.00 35.80  ? 228 LEU R CD1 1 
ATOM 1538 C CD2 . LEU A 1 284 ? 136.433 119.204 99.196  1.00 35.80  ? 228 LEU R CD2 1 
ATOM 1539 N N   . PHE A 1 285 ? 138.823 121.785 103.228 1.00 69.49  ? 229 PHE R N   1 
ATOM 1540 C CA  . PHE A 1 285 ? 139.943 121.804 104.166 1.00 69.49  ? 229 PHE R CA  1 
ATOM 1541 C C   . PHE A 1 285 ? 139.561 121.153 105.490 1.00 69.49  ? 229 PHE R C   1 
ATOM 1542 O O   . PHE A 1 285 ? 140.238 120.229 105.971 1.00 69.49  ? 229 PHE R O   1 
ATOM 1543 C CB  . PHE A 1 285 ? 140.384 123.251 104.386 1.00 37.48  ? 229 PHE R CB  1 
ATOM 1544 C CG  . PHE A 1 285 ? 141.346 123.434 105.524 1.00 37.48  ? 229 PHE R CG  1 
ATOM 1545 C CD1 . PHE A 1 285 ? 142.623 122.913 105.466 1.00 37.48  ? 229 PHE R CD1 1 
ATOM 1546 C CD2 . PHE A 1 285 ? 140.968 124.133 106.655 1.00 37.48  ? 229 PHE R CD2 1 
ATOM 1547 C CE1 . PHE A 1 285 ? 143.502 123.090 106.513 1.00 37.48  ? 229 PHE R CE1 1 
ATOM 1548 C CE2 . PHE A 1 285 ? 141.842 124.309 107.702 1.00 37.48  ? 229 PHE R CE2 1 
ATOM 1549 C CZ  . PHE A 1 285 ? 143.108 123.788 107.632 1.00 37.48  ? 229 PHE R CZ  1 
ATOM 1550 N N   . CYS A 1 286 ? 138.461 121.614 106.086 1.00 69.49  ? 230 CYS R N   1 
ATOM 1551 C CA  . CYS A 1 286 ? 138.082 121.148 107.411 1.00 69.49  ? 230 CYS R CA  1 
ATOM 1552 C C   . CYS A 1 286 ? 137.808 119.652 107.409 1.00 69.49  ? 230 CYS R C   1 
ATOM 1553 O O   . CYS A 1 286 ? 138.344 118.913 108.241 1.00 69.49  ? 230 CYS R O   1 
ATOM 1554 C CB  . CYS A 1 286 ? 136.861 121.924 107.890 1.00 41.79  ? 230 CYS R CB  1 
ATOM 1555 S SG  . CYS A 1 286 ? 137.216 123.638 108.306 1.00 41.79  ? 230 CYS R SG  1 
ATOM 1556 N N   . TYR A 1 287 ? 136.980 119.180 106.476 1.00 69.49  ? 231 TYR R N   1 
ATOM 1557 C CA  . TYR A 1 287 ? 136.634 117.768 106.451 1.00 69.49  ? 231 TYR R CA  1 
ATOM 1558 C C   . TYR A 1 287 ? 137.791 116.891 105.997 1.00 69.49  ? 231 TYR R C   1 
ATOM 1559 O O   . TYR A 1 287 ? 137.873 115.742 106.430 1.00 69.49  ? 231 TYR R O   1 
ATOM 1560 C CB  . TYR A 1 287 ? 135.421 117.540 105.555 1.00 39.79  ? 231 TYR R CB  1 
ATOM 1561 C CG  . TYR A 1 287 ? 134.106 117.898 106.207 1.00 39.79  ? 231 TYR R CG  1 
ATOM 1562 C CD1 . TYR A 1 287 ? 133.760 117.384 107.448 1.00 39.79  ? 231 TYR R CD1 1 
ATOM 1563 C CD2 . TYR A 1 287 ? 133.206 118.738 105.578 1.00 39.79  ? 231 TYR R CD2 1 
ATOM 1564 C CE1 . TYR A 1 287 ? 132.565 117.704 108.043 1.00 39.79  ? 231 TYR R CE1 1 
ATOM 1565 C CE2 . TYR A 1 287 ? 132.005 119.061 106.168 1.00 39.79  ? 231 TYR R CE2 1 
ATOM 1566 C CZ  . TYR A 1 287 ? 131.691 118.541 107.398 1.00 39.79  ? 231 TYR R CZ  1 
ATOM 1567 O OH  . TYR A 1 287 ? 130.493 118.865 107.984 1.00 39.79  ? 231 TYR R OH  1 
ATOM 1568 N N   . GLY A 1 288 ? 138.698 117.395 105.161 1.00 69.49  ? 232 GLY R N   1 
ATOM 1569 C CA  . GLY A 1 288 ? 139.866 116.610 104.810 1.00 69.49  ? 232 GLY R CA  1 
ATOM 1570 C C   . GLY A 1 288 ? 140.760 116.360 106.006 1.00 69.49  ? 232 GLY R C   1 
ATOM 1571 O O   . GLY A 1 288 ? 141.198 115.231 106.246 1.00 69.49  ? 232 GLY R O   1 
ATOM 1572 N N   . PHE A 1 289 ? 141.031 117.404 106.788 1.00 69.49  ? 233 PHE R N   1 
ATOM 1573 C CA  . PHE A 1 289 ? 141.853 117.184 107.973 1.00 69.49  ? 233 PHE R CA  1 
ATOM 1574 C C   . PHE A 1 289 ? 141.109 116.366 109.022 1.00 69.49  ? 233 PHE R C   1 
ATOM 1575 O O   . PHE A 1 289 ? 141.723 115.552 109.724 1.00 69.49  ? 233 PHE R O   1 
ATOM 1576 C CB  . PHE A 1 289 ? 142.320 118.517 108.543 1.00 39.77  ? 233 PHE R CB  1 
ATOM 1577 C CG  . PHE A 1 289 ? 143.542 119.056 107.865 1.00 39.77  ? 233 PHE R CG  1 
ATOM 1578 C CD1 . PHE A 1 289 ? 143.481 119.514 106.565 1.00 39.77  ? 233 PHE R CD1 1 
ATOM 1579 C CD2 . PHE A 1 289 ? 144.756 119.079 108.518 1.00 39.77  ? 233 PHE R CD2 1 
ATOM 1580 C CE1 . PHE A 1 289 ? 144.602 120.000 105.936 1.00 39.77  ? 233 PHE R CE1 1 
ATOM 1581 C CE2 . PHE A 1 289 ? 145.880 119.565 107.893 1.00 39.77  ? 233 PHE R CE2 1 
ATOM 1582 C CZ  . PHE A 1 289 ? 145.804 120.025 106.600 1.00 39.77  ? 233 PHE R CZ  1 
ATOM 1583 N N   . THR A 1 290 ? 139.792 116.546 109.130 1.00 69.49  ? 234 THR R N   1 
ATOM 1584 C CA  . THR A 1 290 ? 139.002 115.723 110.038 1.00 69.49  ? 234 THR R CA  1 
ATOM 1585 C C   . THR A 1 290 ? 139.107 114.252 109.665 1.00 69.49  ? 234 THR R C   1 
ATOM 1586 O O   . THR A 1 290 ? 139.277 113.389 110.532 1.00 69.49  ? 234 THR R O   1 
ATOM 1587 C CB  . THR A 1 290 ? 137.546 116.175 110.007 1.00 38.69  ? 234 THR R CB  1 
ATOM 1588 O OG1 . THR A 1 290 ? 137.460 117.544 110.409 1.00 38.69  ? 234 THR R OG1 1 
ATOM 1589 C CG2 . THR A 1 290 ? 136.709 115.334 110.935 1.00 38.69  ? 234 THR R CG2 1 
ATOM 1590 N N   . LEU A 1 291 ? 138.999 113.947 108.373 1.00 69.49  ? 235 LEU R N   1 
ATOM 1591 C CA  . LEU A 1 291 ? 139.135 112.570 107.921 1.00 69.49  ? 235 LEU R CA  1 
ATOM 1592 C C   . LEU A 1 291 ? 140.537 112.045 108.181 1.00 69.49  ? 235 LEU R C   1 
ATOM 1593 O O   . LEU A 1 291 ? 140.707 110.882 108.556 1.00 69.49  ? 235 LEU R O   1 
ATOM 1594 C CB  . LEU A 1 291 ? 138.803 112.471 106.436 1.00 43.47  ? 235 LEU R CB  1 
ATOM 1595 C CG  . LEU A 1 291 ? 137.328 112.597 106.073 1.00 43.47  ? 235 LEU R CG  1 
ATOM 1596 C CD1 . LEU A 1 291 ? 137.182 112.800 104.582 1.00 43.47  ? 235 LEU R CD1 1 
ATOM 1597 C CD2 . LEU A 1 291 ? 136.561 111.374 106.521 1.00 43.47  ? 235 LEU R CD2 1 
ATOM 1598 N N   . ARG A 1 292 ? 141.556 112.879 107.978 1.00 69.49  ? 236 ARG R N   1 
ATOM 1599 C CA  . ARG A 1 292 ? 142.913 112.421 108.246 1.00 69.49  ? 236 ARG R CA  1 
ATOM 1600 C C   . ARG A 1 292 ? 143.082 112.045 109.710 1.00 69.49  ? 236 ARG R C   1 
ATOM 1601 O O   . ARG A 1 292 ? 143.744 111.051 110.026 1.00 69.49  ? 236 ARG R O   1 
ATOM 1602 C CB  . ARG A 1 292 ? 143.929 113.487 107.851 1.00 43.40  ? 236 ARG R CB  1 
ATOM 1603 C CG  . ARG A 1 292 ? 145.302 113.257 108.462 1.00 43.40  ? 236 ARG R CG  1 
ATOM 1604 C CD  . ARG A 1 292 ? 146.400 113.964 107.687 1.00 43.40  ? 236 ARG R CD  1 
ATOM 1605 N NE  . ARG A 1 292 ? 146.493 113.487 106.312 1.00 43.40  ? 236 ARG R NE  1 
ATOM 1606 C CZ  . ARG A 1 292 ? 147.494 113.762 105.487 1.00 43.40  ? 236 ARG R CZ  1 
ATOM 1607 N NH1 . ARG A 1 292 ? 148.526 114.496 105.870 1.00 43.40  ? 236 ARG R NH1 1 
ATOM 1608 N NH2 . ARG A 1 292 ? 147.461 113.284 104.247 1.00 43.40  ? 236 ARG R NH2 1 
ATOM 1609 N N   . THR A 1 293 ? 142.500 112.827 110.623 1.00 69.49  ? 237 THR R N   1 
ATOM 1610 C CA  . THR A 1 293 ? 142.611 112.481 112.040 1.00 69.49  ? 237 THR R CA  1 
ATOM 1611 C C   . THR A 1 293 ? 141.789 111.246 112.380 1.00 69.49  ? 237 THR R C   1 
ATOM 1612 O O   . THR A 1 293 ? 142.245 110.387 113.140 1.00 69.49  ? 237 THR R O   1 
ATOM 1613 C CB  . THR A 1 293 ? 142.178 113.646 112.922 1.00 47.96  ? 237 THR R CB  1 
ATOM 1614 O OG1 . THR A 1 293 ? 140.888 114.105 112.514 1.00 47.96  ? 237 THR R OG1 1 
ATOM 1615 C CG2 . THR A 1 293 ? 143.176 114.777 112.823 1.00 47.96  ? 237 THR R CG2 1 
ATOM 1616 N N   . LEU A 1 294 ? 140.571 111.138 111.844 1.00 69.49  ? 238 LEU R N   1 
ATOM 1617 C CA  . LEU A 1 294 ? 139.741 109.980 112.153 1.00 69.49  ? 238 LEU R CA  1 
ATOM 1618 C C   . LEU A 1 294 ? 140.348 108.686 111.644 1.00 69.49  ? 238 LEU R C   1 
ATOM 1619 O O   . LEU A 1 294 ? 140.338 107.690 112.367 1.00 69.49  ? 238 LEU R O   1 
ATOM 1620 C CB  . LEU A 1 294 ? 138.338 110.137 111.565 1.00 45.78  ? 238 LEU R CB  1 
ATOM 1621 C CG  . LEU A 1 294 ? 137.421 111.179 112.200 1.00 45.78  ? 238 LEU R CG  1 
ATOM 1622 C CD1 . LEU A 1 294 ? 136.248 111.466 111.296 1.00 45.78  ? 238 LEU R CD1 1 
ATOM 1623 C CD2 . LEU A 1 294 ? 136.937 110.720 113.555 1.00 45.78  ? 238 LEU R CD2 1 
ATOM 1624 N N   . PHE A 1 295 ? 140.888 108.679 110.427 1.00 69.49  ? 239 PHE R N   1 
ATOM 1625 C CA  . PHE A 1 295 ? 141.405 107.443 109.855 1.00 69.49  ? 239 PHE R CA  1 
ATOM 1626 C C   . PHE A 1 295 ? 142.511 106.843 110.709 1.00 69.49  ? 239 PHE R C   1 
ATOM 1627 O O   . PHE A 1 295 ? 142.651 105.616 110.759 1.00 69.49  ? 239 PHE R O   1 
ATOM 1628 C CB  . PHE A 1 295 ? 141.918 107.696 108.437 1.00 53.71  ? 239 PHE R CB  1 
ATOM 1629 C CG  . PHE A 1 295 ? 142.477 106.474 107.767 1.00 53.71  ? 239 PHE R CG  1 
ATOM 1630 C CD1 . PHE A 1 295 ? 141.655 105.623 107.049 1.00 53.71  ? 239 PHE R CD1 1 
ATOM 1631 C CD2 . PHE A 1 295 ? 143.827 106.178 107.850 1.00 53.71  ? 239 PHE R CD2 1 
ATOM 1632 C CE1 . PHE A 1 295 ? 142.167 104.500 106.431 1.00 53.71  ? 239 PHE R CE1 1 
ATOM 1633 C CE2 . PHE A 1 295 ? 144.345 105.055 107.233 1.00 53.71  ? 239 PHE R CE2 1 
ATOM 1634 C CZ  . PHE A 1 295 ? 143.513 104.216 106.523 1.00 53.71  ? 239 PHE R CZ  1 
ATOM 1635 N N   . LYS A 1 296 ? 143.293 107.681 111.385 1.00 61.29  ? 240 LYS R N   1 
ATOM 1636 C CA  . LYS A 1 296 ? 144.360 107.228 112.263 1.00 61.29  ? 240 LYS R CA  1 
ATOM 1637 C C   . LYS A 1 296 ? 143.872 106.938 113.675 1.00 61.29  ? 240 LYS R C   1 
ATOM 1638 O O   . LYS A 1 296 ? 144.657 106.474 114.504 1.00 61.29  ? 240 LYS R O   1 
ATOM 1639 C CB  . LYS A 1 296 ? 145.478 108.259 112.298 1.00 30.00  ? 240 LYS R CB  1 
ATOM 1640 N N   . ALA A 1 297 ? 142.601 107.190 113.966 1.00 61.87  ? 241 ALA R N   1 
ATOM 1641 C CA  . ALA A 1 297 ? 142.037 106.912 115.275 1.00 61.87  ? 241 ALA R CA  1 
ATOM 1642 C C   . ALA A 1 297 ? 141.748 105.421 115.422 1.00 61.87  ? 241 ALA R C   1 
ATOM 1643 O O   . ALA A 1 297 ? 141.836 104.644 114.470 1.00 61.87  ? 241 ALA R O   1 
ATOM 1644 C CB  . ALA A 1 297 ? 140.765 107.728 115.493 1.00 61.87  ? 241 ALA R CB  1 
ATOM 1645 N N   . HIS A 1 298 ? 141.406 105.021 116.647 1.00 88.55  ? 242 HIS R N   1 
ATOM 1646 C CA  . HIS A 1 298 ? 141.149 103.625 116.977 1.00 88.55  ? 242 HIS R CA  1 
ATOM 1647 C C   . HIS A 1 298 ? 139.731 103.400 117.491 1.00 88.55  ? 242 HIS R C   1 
ATOM 1648 O O   . HIS A 1 298 ? 139.454 102.365 118.104 1.00 88.55  ? 242 HIS R O   1 
ATOM 1649 C CB  . HIS A 1 298 ? 142.169 103.138 118.008 1.00 88.55  ? 242 HIS R CB  1 
ATOM 1650 C CG  . HIS A 1 298 ? 143.585 103.476 117.659 1.00 88.55  ? 242 HIS R CG  1 
ATOM 1651 N ND1 . HIS A 1 298 ? 144.197 103.024 116.510 1.00 88.55  ? 242 HIS R ND1 1 
ATOM 1652 C CD2 . HIS A 1 298 ? 144.507 104.227 118.306 1.00 88.55  ? 242 HIS R CD2 1 
ATOM 1653 C CE1 . HIS A 1 298 ? 145.436 103.480 116.465 1.00 88.55  ? 242 HIS R CE1 1 
ATOM 1654 N NE2 . HIS A 1 298 ? 145.649 104.213 117.543 1.00 88.55  ? 242 HIS R NE2 1 
ATOM 1655 N N   . MET A 1 299 ? 138.827 104.343 117.249 1.00 68.34  ? 243 MET R N   1 
ATOM 1656 C CA  . MET A 1 299 ? 137.467 104.217 117.746 1.00 68.34  ? 243 MET R CA  1 
ATOM 1657 C C   . MET A 1 299 ? 136.716 103.125 116.998 1.00 68.34  ? 243 MET R C   1 
ATOM 1658 O O   . MET A 1 299 ? 137.127 102.678 115.924 1.00 68.34  ? 243 MET R O   1 
ATOM 1659 C CB  . MET A 1 299 ? 136.716 105.538 117.597 1.00 68.34  ? 243 MET R CB  1 
ATOM 1660 C CG  . MET A 1 299 ? 137.413 106.724 118.229 1.00 68.34  ? 243 MET R CG  1 
ATOM 1661 S SD  . MET A 1 299 ? 136.886 108.296 117.539 1.00 68.34  ? 243 MET R SD  1 
ATOM 1662 C CE  . MET A 1 299 ? 137.244 108.044 115.807 1.00 68.34  ? 243 MET R CE  1 
ATOM 1663 N N   . GLY A 1 300 ? 135.605 102.686 117.591 1.00 64.41  ? 244 GLY R N   1 
ATOM 1664 C CA  . GLY A 1 300 ? 134.728 101.756 116.907 1.00 64.41  ? 244 GLY R CA  1 
ATOM 1665 C C   . GLY A 1 300 ? 133.721 102.435 116.008 1.00 64.41  ? 244 GLY R C   1 
ATOM 1666 O O   . GLY A 1 300 ? 133.190 101.806 115.088 1.00 64.41  ? 244 GLY R O   1 
ATOM 1667 N N   . GLN A 1 301 ? 133.443 103.715 116.249 1.00 69.49  ? 245 GLN R N   1 
ATOM 1668 C CA  . GLN A 1 301 ? 132.487 104.470 115.453 1.00 69.49  ? 245 GLN R CA  1 
ATOM 1669 C C   . GLN A 1 301 ? 133.165 105.412 114.470 1.00 69.49  ? 245 GLN R C   1 
ATOM 1670 O O   . GLN A 1 301 ? 132.517 106.328 113.956 1.00 69.49  ? 245 GLN R O   1 
ATOM 1671 C CB  . GLN A 1 301 ? 131.547 105.267 116.356 1.00 69.49  ? 245 GLN R CB  1 
ATOM 1672 C CG  . GLN A 1 301 ? 131.042 104.517 117.569 1.00 69.49  ? 245 GLN R CG  1 
ATOM 1673 C CD  . GLN A 1 301 ? 131.822 104.858 118.819 1.00 69.49  ? 245 GLN R CD  1 
ATOM 1674 O OE1 . GLN A 1 301 ? 131.752 105.980 119.319 1.00 69.49  ? 245 GLN R OE1 1 
ATOM 1675 N NE2 . GLN A 1 301 ? 132.573 103.892 119.331 1.00 69.49  ? 245 GLN R NE2 1 
ATOM 1676 N N   . LYS A 1 302 ? 134.457 105.221 114.206 1.00 69.49  ? 246 LYS R N   1 
ATOM 1677 C CA  . LYS A 1 302 ? 135.125 106.063 113.221 1.00 69.49  ? 246 LYS R CA  1 
ATOM 1678 C C   . LYS A 1 302 ? 134.501 105.882 111.847 1.00 69.49  ? 246 LYS R C   1 
ATOM 1679 O O   . LYS A 1 302 ? 134.325 106.854 111.104 1.00 69.49  ? 246 LYS R O   1 
ATOM 1680 C CB  . LYS A 1 302 ? 136.615 105.737 113.165 1.00 57.17  ? 246 LYS R CB  1 
ATOM 1681 C CG  . LYS A 1 302 ? 136.903 104.326 112.697 1.00 57.17  ? 246 LYS R CG  1 
ATOM 1682 C CD  . LYS A 1 302 ? 138.336 103.915 112.949 1.00 57.17  ? 246 LYS R CD  1 
ATOM 1683 C CE  . LYS A 1 302 ? 139.299 104.790 112.179 1.00 57.17  ? 246 LYS R CE  1 
ATOM 1684 N NZ  . LYS A 1 302 ? 140.547 104.068 111.807 1.00 57.17  ? 246 LYS R NZ  1 
ATOM 1685 N N   . HIS A 1 303 ? 134.162 104.642 111.495 1.00 69.49  ? 247 HIS R N   1 
ATOM 1686 C CA  . HIS A 1 303 ? 133.720 104.336 110.140 1.00 69.49  ? 247 HIS R CA  1 
ATOM 1687 C C   . HIS A 1 303 ? 132.416 105.048 109.809 1.00 69.49  ? 247 HIS R C   1 
ATOM 1688 O O   . HIS A 1 303 ? 132.263 105.625 108.727 1.00 69.49  ? 247 HIS R O   1 
ATOM 1689 C CB  . HIS A 1 303 ? 133.578 102.825 109.985 1.00 69.49  ? 247 HIS R CB  1 
ATOM 1690 C CG  . HIS A 1 303 ? 134.861 102.082 110.189 1.00 69.49  ? 247 HIS R CG  1 
ATOM 1691 N ND1 . HIS A 1 303 ? 135.079 101.257 111.270 1.00 69.49  ? 247 HIS R ND1 1 
ATOM 1692 C CD2 . HIS A 1 303 ? 135.997 102.048 109.454 1.00 69.49  ? 247 HIS R CD2 1 
ATOM 1693 C CE1 . HIS A 1 303 ? 136.293 100.743 111.190 1.00 69.49  ? 247 HIS R CE1 1 
ATOM 1694 N NE2 . HIS A 1 303 ? 136.871 101.206 110.097 1.00 69.49  ? 247 HIS R NE2 1 
ATOM 1695 N N   . ARG A 1 304 ? 131.456 105.017 110.731 1.00 69.49  ? 248 ARG R N   1 
ATOM 1696 C CA  . ARG A 1 304 ? 130.197 105.703 110.479 1.00 69.49  ? 248 ARG R CA  1 
ATOM 1697 C C   . ARG A 1 304 ? 130.415 107.202 110.335 1.00 69.49  ? 248 ARG R C   1 
ATOM 1698 O O   . ARG A 1 304 ? 129.783 107.851 109.495 1.00 69.49  ? 248 ARG R O   1 
ATOM 1699 C CB  . ARG A 1 304 ? 129.198 105.416 111.596 1.00 69.49  ? 248 ARG R CB  1 
ATOM 1700 C CG  . ARG A 1 304 ? 127.871 106.109 111.382 1.00 69.49  ? 248 ARG R CG  1 
ATOM 1701 C CD  . ARG A 1 304 ? 126.767 105.509 112.220 1.00 69.49  ? 248 ARG R CD  1 
ATOM 1702 N NE  . ARG A 1 304 ? 125.454 105.864 111.692 1.00 69.49  ? 248 ARG R NE  1 
ATOM 1703 C CZ  . ARG A 1 304 ? 124.625 106.745 112.236 1.00 69.49  ? 248 ARG R CZ  1 
ATOM 1704 N NH1 . ARG A 1 304 ? 124.941 107.414 113.333 1.00 69.49  ? 248 ARG R NH1 1 
ATOM 1705 N NH2 . ARG A 1 304 ? 123.447 106.966 111.661 1.00 69.49  ? 248 ARG R NH2 1 
ATOM 1706 N N   . ALA A 1 305 ? 131.303 107.772 111.151 1.00 69.49  ? 249 ALA R N   1 
ATOM 1707 C CA  . ALA A 1 305 ? 131.590 109.197 111.046 1.00 69.49  ? 249 ALA R CA  1 
ATOM 1708 C C   . ALA A 1 305 ? 132.200 109.537 109.694 1.00 69.49  ? 249 ALA R C   1 
ATOM 1709 O O   . ALA A 1 305 ? 131.848 110.552 109.083 1.00 69.49  ? 249 ALA R O   1 
ATOM 1710 C CB  . ALA A 1 305 ? 132.522 109.622 112.176 1.00 42.61  ? 249 ALA R CB  1 
ATOM 1711 N N   . MET A 1 306 ? 133.119 108.701 109.214 1.00 69.49  ? 250 MET R N   1 
ATOM 1712 C CA  . MET A 1 306 ? 133.719 108.938 107.907 1.00 69.49  ? 250 MET R CA  1 
ATOM 1713 C C   . MET A 1 306 ? 132.677 108.851 106.799 1.00 69.49  ? 250 MET R C   1 
ATOM 1714 O O   . MET A 1 306 ? 132.673 109.673 105.874 1.00 69.49  ? 250 MET R O   1 
ATOM 1715 C CB  . MET A 1 306 ? 134.843 107.937 107.667 1.00 69.49  ? 250 MET R CB  1 
ATOM 1716 C CG  . MET A 1 306 ? 136.027 108.116 108.592 1.00 69.49  ? 250 MET R CG  1 
ATOM 1717 S SD  . MET A 1 306 ? 137.255 106.821 108.387 1.00 69.49  ? 250 MET R SD  1 
ATOM 1718 C CE  . MET A 1 306 ? 138.449 107.666 107.356 1.00 69.49  ? 250 MET R CE  1 
ATOM 1719 N N   . ARG A 1 307 ? 131.786 107.862 106.872 1.00 69.49  ? 251 ARG R N   1 
ATOM 1720 C CA  . ARG A 1 307 ? 130.724 107.767 105.876 1.00 69.49  ? 251 ARG R CA  1 
ATOM 1721 C C   . ARG A 1 307 ? 129.832 108.999 105.908 1.00 69.49  ? 251 ARG R C   1 
ATOM 1722 O O   . ARG A 1 307 ? 129.433 109.511 104.858 1.00 69.49  ? 251 ARG R O   1 
ATOM 1723 C CB  . ARG A 1 307 ? 129.892 106.507 106.101 1.00 69.49  ? 251 ARG R CB  1 
ATOM 1724 C CG  . ARG A 1 307 ? 130.672 105.217 105.980 1.00 69.49  ? 251 ARG R CG  1 
ATOM 1725 C CD  . ARG A 1 307 ? 129.801 104.090 105.477 1.00 69.49  ? 251 ARG R CD  1 
ATOM 1726 N NE  . ARG A 1 307 ? 130.215 102.804 106.023 1.00 69.49  ? 251 ARG R NE  1 
ATOM 1727 C CZ  . ARG A 1 307 ? 131.359 102.199 105.735 1.00 69.49  ? 251 ARG R CZ  1 
ATOM 1728 N NH1 . ARG A 1 307 ? 132.228 102.727 104.890 1.00 69.49  ? 251 ARG R NH1 1 
ATOM 1729 N NH2 . ARG A 1 307 ? 131.637 101.032 106.308 1.00 69.49  ? 251 ARG R NH2 1 
ATOM 1730 N N   . VAL A 1 308 ? 129.498 109.486 107.103 1.00 69.49  ? 252 VAL R N   1 
ATOM 1731 C CA  . VAL A 1 308 ? 128.634 110.659 107.203 1.00 69.49  ? 252 VAL R CA  1 
ATOM 1732 C C   . VAL A 1 308 ? 129.325 111.882 106.616 1.00 69.49  ? 252 VAL R C   1 
ATOM 1733 O O   . VAL A 1 308 ? 128.696 112.698 105.935 1.00 69.49  ? 252 VAL R O   1 
ATOM 1734 C CB  . VAL A 1 308 ? 128.215 110.892 108.664 1.00 69.49  ? 252 VAL R CB  1 
ATOM 1735 C CG1 . VAL A 1 308 ? 127.526 112.229 108.805 1.00 69.49  ? 252 VAL R CG1 1 
ATOM 1736 C CG2 . VAL A 1 308 ? 127.301 109.783 109.133 1.00 69.49  ? 252 VAL R CG2 1 
ATOM 1737 N N   . ILE A 1 309 ? 130.623 112.040 106.879 1.00 69.49  ? 253 ILE R N   1 
ATOM 1738 C CA  . ILE A 1 309 ? 131.357 113.166 106.308 1.00 69.49  ? 253 ILE R CA  1 
ATOM 1739 C C   . ILE A 1 309 ? 131.357 113.084 104.789 1.00 69.49  ? 253 ILE R C   1 
ATOM 1740 O O   . ILE A 1 309 ? 131.127 114.087 104.094 1.00 69.49  ? 253 ILE R O   1 
ATOM 1741 C CB  . ILE A 1 309 ? 132.789 113.203 106.870 1.00 69.49  ? 253 ILE R CB  1 
ATOM 1742 C CG1 . ILE A 1 309 ? 132.789 113.768 108.291 1.00 69.49  ? 253 ILE R CG1 1 
ATOM 1743 C CG2 . ILE A 1 309 ? 133.693 114.020 105.967 1.00 69.49  ? 253 ILE R CG2 1 
ATOM 1744 C CD1 . ILE A 1 309 ? 134.097 113.593 109.018 1.00 69.49  ? 253 ILE R CD1 1 
ATOM 1745 N N   . PHE A 1 310 ? 131.623 111.894 104.247 1.00 69.49  ? 254 PHE R N   1 
ATOM 1746 C CA  . PHE A 1 310 ? 131.604 111.727 102.799 1.00 69.49  ? 254 PHE R CA  1 
ATOM 1747 C C   . PHE A 1 310 ? 130.237 112.076 102.232 1.00 69.49  ? 254 PHE R C   1 
ATOM 1748 O O   . PHE A 1 310 ? 130.138 112.754 101.205 1.00 69.49  ? 254 PHE R O   1 
ATOM 1749 C CB  . PHE A 1 310 ? 131.975 110.292 102.426 1.00 69.49  ? 254 PHE R CB  1 
ATOM 1750 C CG  . PHE A 1 310 ? 133.440 110.081 102.180 1.00 69.49  ? 254 PHE R CG  1 
ATOM 1751 C CD1 . PHE A 1 310 ? 134.127 110.861 101.269 1.00 69.49  ? 254 PHE R CD1 1 
ATOM 1752 C CD2 . PHE A 1 310 ? 134.129 109.089 102.855 1.00 69.49  ? 254 PHE R CD2 1 
ATOM 1753 C CE1 . PHE A 1 310 ? 135.471 110.660 101.043 1.00 69.49  ? 254 PHE R CE1 1 
ATOM 1754 C CE2 . PHE A 1 310 ? 135.474 108.884 102.633 1.00 69.49  ? 254 PHE R CE2 1 
ATOM 1755 C CZ  . PHE A 1 310 ? 136.146 109.670 101.727 1.00 69.49  ? 254 PHE R CZ  1 
ATOM 1756 N N   . ALA A 1 311 ? 129.173 111.614 102.884 1.00 69.49  ? 255 ALA R N   1 
ATOM 1757 C CA  . ALA A 1 311 ? 127.830 111.898 102.397 1.00 69.49  ? 255 ALA R CA  1 
ATOM 1758 C C   . ALA A 1 311 ? 127.550 113.391 102.418 1.00 69.49  ? 255 ALA R C   1 
ATOM 1759 O O   . ALA A 1 311 ? 126.965 113.934 101.478 1.00 69.49  ? 255 ALA R O   1 
ATOM 1760 C CB  . ALA A 1 311 ? 126.798 111.147 103.236 1.00 69.49  ? 255 ALA R CB  1 
ATOM 1761 N N   . VAL A 1 312 ? 127.956 114.075 103.485 1.00 69.49  ? 256 VAL R N   1 
ATOM 1762 C CA  . VAL A 1 312 ? 127.730 115.514 103.568 1.00 69.49  ? 256 VAL R CA  1 
ATOM 1763 C C   . VAL A 1 312 ? 128.405 116.220 102.400 1.00 69.49  ? 256 VAL R C   1 
ATOM 1764 O O   . VAL A 1 312 ? 127.789 117.034 101.696 1.00 69.49  ? 256 VAL R O   1 
ATOM 1765 C CB  . VAL A 1 312 ? 128.237 116.053 104.917 1.00 69.49  ? 256 VAL R CB  1 
ATOM 1766 C CG1 . VAL A 1 312 ? 128.280 117.560 104.892 1.00 69.49  ? 256 VAL R CG1 1 
ATOM 1767 C CG2 . VAL A 1 312 ? 127.362 115.566 106.048 1.00 69.49  ? 256 VAL R CG2 1 
ATOM 1768 N N   . VAL A 1 313 ? 129.682 115.910 102.167 1.00 69.49  ? 257 VAL R N   1 
ATOM 1769 C CA  . VAL A 1 313 ? 130.418 116.588 101.101 1.00 69.49  ? 257 VAL R CA  1 
ATOM 1770 C C   . VAL A 1 313 ? 129.799 116.279 99.741  1.00 69.49  ? 257 VAL R C   1 
ATOM 1771 O O   . VAL A 1 313 ? 129.623 117.171 98.899  1.00 69.49  ? 257 VAL R O   1 
ATOM 1772 C CB  . VAL A 1 313 ? 131.905 116.202 101.143 1.00 69.49  ? 257 VAL R CB  1 
ATOM 1773 C CG1 . VAL A 1 313 ? 132.642 116.818 99.968  1.00 69.49  ? 257 VAL R CG1 1 
ATOM 1774 C CG2 . VAL A 1 313 ? 132.525 116.652 102.449 1.00 69.49  ? 257 VAL R CG2 1 
ATOM 1775 N N   . LEU A 1 314 ? 129.468 115.008 99.501  1.00 69.49  ? 258 LEU R N   1 
ATOM 1776 C CA  . LEU A 1 314 ? 128.915 114.627 98.206  1.00 69.49  ? 258 LEU R CA  1 
ATOM 1777 C C   . LEU A 1 314 ? 127.562 115.275 97.968  1.00 69.49  ? 258 LEU R C   1 
ATOM 1778 O O   . LEU A 1 314 ? 127.255 115.676 96.843  1.00 69.49  ? 258 LEU R O   1 
ATOM 1779 C CB  . LEU A 1 314 ? 128.799 113.107 98.099  1.00 69.49  ? 258 LEU R CB  1 
ATOM 1780 C CG  . LEU A 1 314 ? 130.109 112.341 97.910  1.00 69.49  ? 258 LEU R CG  1 
ATOM 1781 C CD1 . LEU A 1 314 ? 129.851 110.844 97.960  1.00 69.49  ? 258 LEU R CD1 1 
ATOM 1782 C CD2 . LEU A 1 314 ? 130.790 112.721 96.605  1.00 69.49  ? 258 LEU R CD2 1 
ATOM 1783 N N   . ILE A 1 315 ? 126.725 115.370 99.001  1.00 69.49  ? 259 ILE R N   1 
ATOM 1784 C CA  . ILE A 1 315 ? 125.429 116.017 98.831  1.00 69.49  ? 259 ILE R CA  1 
ATOM 1785 C C   . ILE A 1 315 ? 125.612 117.494 98.523  1.00 69.49  ? 259 ILE R C   1 
ATOM 1786 O O   . ILE A 1 315 ? 124.928 118.047 97.654  1.00 69.49  ? 259 ILE R O   1 
ATOM 1787 C CB  . ILE A 1 315 ? 124.548 115.803 100.073 1.00 69.49  ? 259 ILE R CB  1 
ATOM 1788 C CG1 . ILE A 1 315 ? 124.188 114.322 100.228 1.00 69.49  ? 259 ILE R CG1 1 
ATOM 1789 C CG2 . ILE A 1 315 ? 123.298 116.654 99.972  1.00 69.49  ? 259 ILE R CG2 1 
ATOM 1790 C CD1 . ILE A 1 315 ? 123.331 113.760 99.117  1.00 69.49  ? 259 ILE R CD1 1 
ATOM 1791 N N   . PHE A 1 316 ? 126.532 118.163 99.223  1.00 69.49  ? 260 PHE R N   1 
ATOM 1792 C CA  . PHE A 1 316 ? 126.791 119.567 98.915  1.00 69.49  ? 260 PHE R CA  1 
ATOM 1793 C C   . PHE A 1 316 ? 127.205 119.735 97.458  1.00 69.49  ? 260 PHE R C   1 
ATOM 1794 O O   . PHE A 1 316 ? 126.684 120.604 96.743  1.00 69.49  ? 260 PHE R O   1 
ATOM 1795 C CB  . PHE A 1 316 ? 127.869 120.118 99.848  1.00 69.49  ? 260 PHE R CB  1 
ATOM 1796 C CG  . PHE A 1 316 ? 128.226 121.555 99.586  1.00 69.49  ? 260 PHE R CG  1 
ATOM 1797 C CD1 . PHE A 1 316 ? 129.177 121.886 98.640  1.00 69.49  ? 260 PHE R CD1 1 
ATOM 1798 C CD2 . PHE A 1 316 ? 127.615 122.573 100.291 1.00 69.49  ? 260 PHE R CD2 1 
ATOM 1799 C CE1 . PHE A 1 316 ? 129.507 123.202 98.400  1.00 69.49  ? 260 PHE R CE1 1 
ATOM 1800 C CE2 . PHE A 1 316 ? 127.944 123.891 100.054 1.00 69.49  ? 260 PHE R CE2 1 
ATOM 1801 C CZ  . PHE A 1 316 ? 128.890 124.204 99.107  1.00 69.49  ? 260 PHE R CZ  1 
ATOM 1802 N N   . LEU A 1 317 ? 128.141 118.903 96.997  1.00 69.49  ? 261 LEU R N   1 
ATOM 1803 C CA  . LEU A 1 317 ? 128.593 119.009 95.614  1.00 69.49  ? 261 LEU R CA  1 
ATOM 1804 C C   . LEU A 1 317 ? 127.450 118.741 94.645  1.00 69.49  ? 261 LEU R C   1 
ATOM 1805 O O   . LEU A 1 317 ? 127.184 119.546 93.751  1.00 69.49  ? 261 LEU R O   1 
ATOM 1806 C CB  . LEU A 1 317 ? 129.752 118.046 95.358  1.00 69.49  ? 261 LEU R CB  1 
ATOM 1807 C CG  . LEU A 1 317 ? 131.136 118.490 95.832  1.00 69.49  ? 261 LEU R CG  1 
ATOM 1808 C CD1 . LEU A 1 317 ? 132.170 117.442 95.477  1.00 69.49  ? 261 LEU R CD1 1 
ATOM 1809 C CD2 . LEU A 1 317 ? 131.521 119.827 95.235  1.00 69.49  ? 261 LEU R CD2 1 
ATOM 1810 N N   . LEU A 1 318 ? 126.741 117.627 94.824  1.00 69.49  ? 262 LEU R N   1 
ATOM 1811 C CA  . LEU A 1 318 ? 125.635 117.303 93.930  1.00 69.49  ? 262 LEU R CA  1 
ATOM 1812 C C   . LEU A 1 318 ? 124.629 118.440 93.865  1.00 69.49  ? 262 LEU R C   1 
ATOM 1813 O O   . LEU A 1 318 ? 124.088 118.739 92.796  1.00 69.49  ? 262 LEU R O   1 
ATOM 1814 C CB  . LEU A 1 318 ? 124.951 116.017 94.392  1.00 69.49  ? 262 LEU R CB  1 
ATOM 1815 C CG  . LEU A 1 318 ? 123.736 115.559 93.583  1.00 69.49  ? 262 LEU R CG  1 
ATOM 1816 C CD1 . LEU A 1 318 ? 124.157 115.070 92.209  1.00 69.49  ? 262 LEU R CD1 1 
ATOM 1817 C CD2 . LEU A 1 318 ? 122.987 114.475 94.334  1.00 69.49  ? 262 LEU R CD2 1 
ATOM 1818 N N   . CYS A 1 319 ? 124.361 119.086 94.998  1.00 69.49  ? 263 CYS R N   1 
ATOM 1819 C CA  . CYS A 1 319 ? 123.357 120.140 95.008  1.00 69.49  ? 263 CYS R CA  1 
ATOM 1820 C C   . CYS A 1 319 ? 123.839 121.382 94.273  1.00 69.49  ? 263 CYS R C   1 
ATOM 1821 O O   . CYS A 1 319 ? 123.083 121.972 93.493  1.00 69.49  ? 263 CYS R O   1 
ATOM 1822 C CB  . CYS A 1 319 ? 122.979 120.488 96.446  1.00 69.49  ? 263 CYS R CB  1 
ATOM 1823 S SG  . CYS A 1 319 ? 121.827 119.330 97.205  1.00 69.49  ? 263 CYS R SG  1 
ATOM 1824 N N   . TRP A 1 320 ? 125.087 121.798 94.493  1.00 69.49  ? 264 TRP R N   1 
ATOM 1825 C CA  . TRP A 1 320 ? 125.483 123.141 94.084  1.00 69.49  ? 264 TRP R CA  1 
ATOM 1826 C C   . TRP A 1 320 ? 126.471 123.210 92.928  1.00 69.49  ? 264 TRP R C   1 
ATOM 1827 O O   . TRP A 1 320 ? 126.485 124.217 92.222  1.00 69.49  ? 264 TRP R O   1 
ATOM 1828 C CB  . TRP A 1 320 ? 126.068 123.897 95.280  1.00 69.49  ? 264 TRP R CB  1 
ATOM 1829 C CG  . TRP A 1 320 ? 125.029 124.216 96.305  1.00 69.49  ? 264 TRP R CG  1 
ATOM 1830 C CD1 . TRP A 1 320 ? 125.026 123.839 97.612  1.00 69.49  ? 264 TRP R CD1 1 
ATOM 1831 C CD2 . TRP A 1 320 ? 123.827 124.965 96.100  1.00 69.49  ? 264 TRP R CD2 1 
ATOM 1832 N NE1 . TRP A 1 320 ? 123.901 124.310 98.237  1.00 69.49  ? 264 TRP R NE1 1 
ATOM 1833 C CE2 . TRP A 1 320 ? 123.148 125.005 97.329  1.00 69.49  ? 264 TRP R CE2 1 
ATOM 1834 C CE3 . TRP A 1 320 ? 123.261 125.608 94.997  1.00 69.49  ? 264 TRP R CE3 1 
ATOM 1835 C CZ2 . TRP A 1 320 ? 121.935 125.664 97.486  1.00 69.49  ? 264 TRP R CZ2 1 
ATOM 1836 C CZ3 . TRP A 1 320 ? 122.056 126.259 95.156  1.00 69.49  ? 264 TRP R CZ3 1 
ATOM 1837 C CH2 . TRP A 1 320 ? 121.406 126.283 96.390  1.00 69.49  ? 264 TRP R CH2 1 
ATOM 1838 N N   . LEU A 1 321 ? 127.305 122.197 92.710  1.00 69.49  ? 265 LEU R N   1 
ATOM 1839 C CA  . LEU A 1 321 ? 128.294 122.290 91.639  1.00 69.49  ? 265 LEU R CA  1 
ATOM 1840 C C   . LEU A 1 321 ? 127.656 122.396 90.262  1.00 69.49  ? 265 LEU R C   1 
ATOM 1841 O O   . LEU A 1 321 ? 128.109 123.233 89.463  1.00 69.49  ? 265 LEU R O   1 
ATOM 1842 C CB  . LEU A 1 321 ? 129.254 121.099 91.720  1.00 69.49  ? 265 LEU R CB  1 
ATOM 1843 C CG  . LEU A 1 321 ? 130.357 121.050 90.662  1.00 69.49  ? 265 LEU R CG  1 
ATOM 1844 C CD1 . LEU A 1 321 ? 131.388 122.128 90.910  1.00 69.49  ? 265 LEU R CD1 1 
ATOM 1845 C CD2 . LEU A 1 321 ? 131.012 119.685 90.654  1.00 69.49  ? 265 LEU R CD2 1 
ATOM 1846 N N   . PRO A 1 322 ? 126.656 121.589 89.898  1.00 69.49  ? 266 PRO R N   1 
ATOM 1847 C CA  . PRO A 1 322 ? 126.074 121.727 88.551  1.00 69.49  ? 266 PRO R CA  1 
ATOM 1848 C C   . PRO A 1 322 ? 125.525 123.114 88.259  1.00 69.49  ? 266 PRO R C   1 
ATOM 1849 O O   . PRO A 1 322 ? 125.740 123.652 87.164  1.00 69.49  ? 266 PRO R O   1 
ATOM 1850 C CB  . PRO A 1 322 ? 124.973 120.660 88.557  1.00 69.49  ? 266 PRO R CB  1 
ATOM 1851 C CG  . PRO A 1 322 ? 125.457 119.647 89.521  1.00 69.49  ? 266 PRO R CG  1 
ATOM 1852 C CD  . PRO A 1 322 ? 126.056 120.459 90.624  1.00 69.49  ? 266 PRO R CD  1 
ATOM 1853 N N   . TYR A 1 323 ? 124.825 123.714 89.222  1.00 69.49  ? 267 TYR R N   1 
ATOM 1854 C CA  . TYR A 1 323 ? 124.254 125.038 89.001  1.00 69.49  ? 267 TYR R CA  1 
ATOM 1855 C C   . TYR A 1 323 ? 125.343 126.067 88.745  1.00 69.49  ? 267 TYR R C   1 
ATOM 1856 O O   . TYR A 1 323 ? 125.225 126.895 87.837  1.00 69.49  ? 267 TYR R O   1 
ATOM 1857 C CB  . TYR A 1 323 ? 123.407 125.444 90.205  1.00 69.49  ? 267 TYR R CB  1 
ATOM 1858 C CG  . TYR A 1 323 ? 122.770 126.808 90.083  1.00 69.49  ? 267 TYR R CG  1 
ATOM 1859 C CD1 . TYR A 1 323 ? 121.729 127.032 89.195  1.00 69.49  ? 267 TYR R CD1 1 
ATOM 1860 C CD2 . TYR A 1 323 ? 123.197 127.866 90.867  1.00 69.49  ? 267 TYR R CD2 1 
ATOM 1861 C CE1 . TYR A 1 323 ? 121.141 128.273 89.085  1.00 69.49  ? 267 TYR R CE1 1 
ATOM 1862 C CE2 . TYR A 1 323 ? 122.615 129.111 90.764  1.00 69.49  ? 267 TYR R CE2 1 
ATOM 1863 C CZ  . TYR A 1 323 ? 121.587 129.309 89.871  1.00 69.49  ? 267 TYR R CZ  1 
ATOM 1864 O OH  . TYR A 1 323 ? 121.002 130.549 89.763  1.00 69.49  ? 267 TYR R OH  1 
ATOM 1865 N N   . ASN A 1 324 ? 126.420 126.022 89.527  1.00 69.49  ? 268 ASN R N   1 
ATOM 1866 C CA  . ASN A 1 324 ? 127.483 127.001 89.358  1.00 69.49  ? 268 ASN R CA  1 
ATOM 1867 C C   . ASN A 1 324 ? 128.286 126.747 88.089  1.00 69.49  ? 268 ASN R C   1 
ATOM 1868 O O   . ASN A 1 324 ? 128.763 127.697 87.464  1.00 69.49  ? 268 ASN R O   1 
ATOM 1869 C CB  . ASN A 1 324 ? 128.386 126.996 90.585  1.00 69.49  ? 268 ASN R CB  1 
ATOM 1870 C CG  . ASN A 1 324 ? 127.745 127.681 91.771  1.00 69.49  ? 268 ASN R CG  1 
ATOM 1871 O OD1 . ASN A 1 324 ? 128.097 128.806 92.118  1.00 69.49  ? 268 ASN R OD1 1 
ATOM 1872 N ND2 . ASN A 1 324 ? 126.795 127.005 92.399  1.00 69.49  ? 268 ASN R ND2 1 
ATOM 1873 N N   . LEU A 1 325 ? 128.440 125.486 87.684  1.00 69.49  ? 269 LEU R N   1 
ATOM 1874 C CA  . LEU A 1 325 ? 129.069 125.209 86.397  1.00 69.49  ? 269 LEU R CA  1 
ATOM 1875 C C   . LEU A 1 325 ? 128.246 125.781 85.253  1.00 69.49  ? 269 LEU R C   1 
ATOM 1876 O O   . LEU A 1 325 ? 128.794 126.389 84.326  1.00 69.49  ? 269 LEU R O   1 
ATOM 1877 C CB  . LEU A 1 325 ? 129.254 123.704 86.210  1.00 69.49  ? 269 LEU R CB  1 
ATOM 1878 C CG  . LEU A 1 325 ? 130.440 123.054 86.917  1.00 69.49  ? 269 LEU R CG  1 
ATOM 1879 C CD1 . LEU A 1 325 ? 130.374 121.551 86.755  1.00 69.49  ? 269 LEU R CD1 1 
ATOM 1880 C CD2 . LEU A 1 325 ? 131.752 123.585 86.373  1.00 69.49  ? 269 LEU R CD2 1 
ATOM 1881 N N   . VAL A 1 326 ? 126.926 125.600 85.297  1.00 69.49  ? 270 VAL R N   1 
ATOM 1882 C CA  . VAL A 1 326 ? 126.080 126.155 84.246  1.00 69.49  ? 270 VAL R CA  1 
ATOM 1883 C C   . VAL A 1 326 ? 126.139 127.676 84.266  1.00 69.49  ? 270 VAL R C   1 
ATOM 1884 O O   . VAL A 1 326 ? 126.156 128.327 83.214  1.00 69.49  ? 270 VAL R O   1 
ATOM 1885 C CB  . VAL A 1 326 ? 124.638 125.644 84.393  1.00 69.49  ? 270 VAL R CB  1 
ATOM 1886 C CG1 . VAL A 1 326 ? 123.723 126.389 83.449  1.00 69.49  ? 270 VAL R CG1 1 
ATOM 1887 C CG2 . VAL A 1 326 ? 124.577 124.155 84.123  1.00 69.49  ? 270 VAL R CG2 1 
ATOM 1888 N N   . LEU A 1 327 ? 126.164 128.268 85.459  1.00 69.49  ? 271 LEU R N   1 
ATOM 1889 C CA  . LEU A 1 327 ? 126.251 129.718 85.562  1.00 69.49  ? 271 LEU R CA  1 
ATOM 1890 C C   . LEU A 1 327 ? 127.559 130.235 84.976  1.00 69.49  ? 271 LEU R C   1 
ATOM 1891 O O   . LEU A 1 327 ? 127.574 131.247 84.266  1.00 69.49  ? 271 LEU R O   1 
ATOM 1892 C CB  . LEU A 1 327 ? 126.111 130.132 87.024  1.00 65.27  ? 271 LEU R CB  1 
ATOM 1893 C CG  . LEU A 1 327 ? 125.372 131.437 87.290  1.00 65.27  ? 271 LEU R CG  1 
ATOM 1894 C CD1 . LEU A 1 327 ? 123.921 131.339 86.860  1.00 65.27  ? 271 LEU R CD1 1 
ATOM 1895 C CD2 . LEU A 1 327 ? 125.469 131.806 88.758  1.00 65.27  ? 271 LEU R CD2 1 
ATOM 1896 N N   . LEU A 1 328 ? 128.670 129.554 85.261  1.00 69.49  ? 272 LEU R N   1 
ATOM 1897 C CA  . LEU A 1 328 ? 129.947 129.939 84.673  1.00 69.49  ? 272 LEU R CA  1 
ATOM 1898 C C   . LEU A 1 328 ? 129.921 129.784 83.161  1.00 69.49  ? 272 LEU R C   1 
ATOM 1899 O O   . LEU A 1 328 ? 130.498 130.603 82.440  1.00 69.49  ? 272 LEU R O   1 
ATOM 1900 C CB  . LEU A 1 328 ? 131.076 129.103 85.274  1.00 67.10  ? 272 LEU R CB  1 
ATOM 1901 C CG  . LEU A 1 328 ? 132.474 129.342 84.701  1.00 67.10  ? 272 LEU R CG  1 
ATOM 1902 C CD1 . LEU A 1 328 ? 133.016 130.686 85.149  1.00 67.10  ? 272 LEU R CD1 1 
ATOM 1903 C CD2 . LEU A 1 328 ? 133.411 128.223 85.112  1.00 67.10  ? 272 LEU R CD2 1 
ATOM 1904 N N   . ALA A 1 329 ? 129.281 128.728 82.661  1.00 69.64  ? 273 ALA R N   1 
ATOM 1905 C CA  . ALA A 1 329 ? 129.168 128.566 81.216  1.00 69.64  ? 273 ALA R CA  1 
ATOM 1906 C C   . ALA A 1 329 ? 128.412 129.733 80.600  1.00 69.64  ? 273 ALA R C   1 
ATOM 1907 O O   . ALA A 1 329 ? 128.817 130.267 79.560  1.00 69.64  ? 273 ALA R O   1 
ATOM 1908 C CB  . ALA A 1 329 ? 128.474 127.247 80.889  1.00 69.64  ? 273 ALA R CB  1 
ATOM 1909 N N   . ASP A 1 330 ? 127.316 130.147 81.235  1.00 75.07  ? 274 ASP R N   1 
ATOM 1910 C CA  . ASP A 1 330 ? 126.564 131.294 80.739  1.00 75.07  ? 274 ASP R CA  1 
ATOM 1911 C C   . ASP A 1 330 ? 127.410 132.560 80.766  1.00 75.07  ? 274 ASP R C   1 
ATOM 1912 O O   . ASP A 1 330 ? 127.399 133.343 79.809  1.00 75.07  ? 274 ASP R O   1 
ATOM 1913 C CB  . ASP A 1 330 ? 125.297 131.485 81.568  1.00 75.07  ? 274 ASP R CB  1 
ATOM 1914 C CG  . ASP A 1 330 ? 124.348 132.492 80.958  1.00 75.07  ? 274 ASP R CG  1 
ATOM 1915 O OD1 . ASP A 1 330 ? 124.698 133.088 79.920  1.00 75.07  ? 274 ASP R OD1 1 
ATOM 1916 O OD2 . ASP A 1 330 ? 123.249 132.689 81.515  1.00 75.07  ? 274 ASP R OD2 1 
ATOM 1917 N N   . THR A 1 331 ? 128.150 132.777 81.853  1.00 70.57  ? 275 THR R N   1 
ATOM 1918 C CA  . THR A 1 331 ? 128.981 133.972 81.957  1.00 70.57  ? 275 THR R CA  1 
ATOM 1919 C C   . THR A 1 331 ? 130.055 133.984 80.878  1.00 70.57  ? 275 THR R C   1 
ATOM 1920 O O   . THR A 1 331 ? 130.352 135.031 80.293  1.00 70.57  ? 275 THR R O   1 
ATOM 1921 C CB  . THR A 1 331 ? 129.616 134.052 83.344  1.00 70.57  ? 275 THR R CB  1 
ATOM 1922 O OG1 . THR A 1 331 ? 128.591 134.211 84.332  1.00 70.57  ? 275 THR R OG1 1 
ATOM 1923 C CG2 . THR A 1 331 ? 130.573 135.225 83.423  1.00 70.57  ? 275 THR R CG2 1 
ATOM 1924 N N   . LEU A 1 332 ? 130.661 132.828 80.612  1.00 73.80  ? 276 LEU R N   1 
ATOM 1925 C CA  . LEU A 1 332 ? 131.645 132.744 79.540  1.00 73.80  ? 276 LEU R CA  1 
ATOM 1926 C C   . LEU A 1 332 ? 131.008 133.034 78.188  1.00 73.80  ? 276 LEU R C   1 
ATOM 1927 O O   . LEU A 1 332 ? 131.589 133.744 77.360  1.00 73.80  ? 276 LEU R O   1 
ATOM 1928 C CB  . LEU A 1 332 ? 132.297 131.363 79.535  1.00 73.80  ? 276 LEU R CB  1 
ATOM 1929 C CG  . LEU A 1 332 ? 133.334 131.113 80.629  1.00 73.80  ? 276 LEU R CG  1 
ATOM 1930 C CD1 . LEU A 1 332 ? 133.322 129.657 81.044  1.00 73.80  ? 276 LEU R CD1 1 
ATOM 1931 C CD2 . LEU A 1 332 ? 134.715 131.517 80.152  1.00 73.80  ? 276 LEU R CD2 1 
ATOM 1932 N N   . MET A 1 333 ? 129.815 132.488 77.943  1.00 83.11  ? 277 MET R N   1 
ATOM 1933 C CA  . MET A 1 333 ? 129.159 132.708 76.658  1.00 83.11  ? 277 MET R CA  1 
ATOM 1934 C C   . MET A 1 333 ? 128.824 134.180 76.450  1.00 83.11  ? 277 MET R C   1 
ATOM 1935 O O   . MET A 1 333 ? 129.028 134.718 75.357  1.00 83.11  ? 277 MET R O   1 
ATOM 1936 C CB  . MET A 1 333 ? 127.895 131.859 76.561  1.00 83.11  ? 277 MET R CB  1 
ATOM 1937 C CG  . MET A 1 333 ? 127.274 131.846 75.178  1.00 83.11  ? 277 MET R CG  1 
ATOM 1938 S SD  . MET A 1 333 ? 125.695 130.986 75.136  1.00 83.11  ? 277 MET R SD  1 
ATOM 1939 C CE  . MET A 1 333 ? 124.634 132.210 75.895  1.00 83.11  ? 277 MET R CE  1 
ATOM 1940 N N   . ARG A 1 334 ? 128.310 134.848 77.484  1.00 74.44  ? 278 ARG R N   1 
ATOM 1941 C CA  . ARG A 1 334 ? 127.934 136.250 77.333  1.00 74.44  ? 278 ARG R CA  1 
ATOM 1942 C C   . ARG A 1 334 ? 129.134 137.126 77.007  1.00 74.44  ? 278 ARG R C   1 
ATOM 1943 O O   . ARG A 1 334 ? 128.981 138.161 76.350  1.00 74.44  ? 278 ARG R O   1 
ATOM 1944 C CB  . ARG A 1 334 ? 127.256 136.753 78.604  1.00 74.44  ? 278 ARG R CB  1 
ATOM 1945 C CG  . ARG A 1 334 ? 125.835 136.275 78.772  1.00 74.44  ? 278 ARG R CG  1 
ATOM 1946 C CD  . ARG A 1 334 ? 125.080 137.133 79.763  1.00 74.44  ? 278 ARG R CD  1 
ATOM 1947 N NE  . ARG A 1 334 ? 123.909 136.440 80.289  1.00 74.44  ? 278 ARG R NE  1 
ATOM 1948 C CZ  . ARG A 1 334 ? 122.650 136.796 80.074  1.00 74.44  ? 278 ARG R CZ  1 
ATOM 1949 N NH1 . ARG A 1 334 ? 122.339 137.846 79.330  1.00 74.44  ? 278 ARG R NH1 1 
ATOM 1950 N NH2 . ARG A 1 334 ? 121.674 136.080 80.620  1.00 74.44  ? 278 ARG R NH2 1 
ATOM 1951 N N   . THR A 1 335 ? 130.326 136.737 77.451  1.00 76.50  ? 279 THR R N   1 
ATOM 1952 C CA  . THR A 1 335 ? 131.533 137.526 77.254  1.00 76.50  ? 279 THR R CA  1 
ATOM 1953 C C   . THR A 1 335 ? 132.277 137.162 75.976  1.00 76.50  ? 279 THR R C   1 
ATOM 1954 O O   . THR A 1 335 ? 133.416 137.602 75.796  1.00 76.50  ? 279 THR R O   1 
ATOM 1955 C CB  . THR A 1 335 ? 132.470 137.356 78.453  1.00 76.50  ? 279 THR R CB  1 
ATOM 1956 O OG1 . THR A 1 335 ? 131.705 137.356 79.663  1.00 76.50  ? 279 THR R OG1 1 
ATOM 1957 C CG2 . THR A 1 335 ? 133.481 138.488 78.513  1.00 76.50  ? 279 THR R CG2 1 
ATOM 1958 N N   . GLN A 1 336 ? 131.676 136.360 75.099  1.00 83.66  ? 280 GLN R N   1 
ATOM 1959 C CA  . GLN A 1 336 ? 132.242 135.962 73.814  1.00 83.66  ? 280 GLN R CA  1 
ATOM 1960 C C   . GLN A 1 336 ? 133.404 134.988 73.954  1.00 83.66  ? 280 GLN R C   1 
ATOM 1961 O O   . GLN A 1 336 ? 134.080 134.700 72.959  1.00 83.66  ? 280 GLN R O   1 
ATOM 1962 C CB  . GLN A 1 336 ? 132.703 137.174 72.995  1.00 83.66  ? 280 GLN R CB  1 
ATOM 1963 C CG  . GLN A 1 336 ? 131.575 138.075 72.523  1.00 83.66  ? 280 GLN R CG  1 
ATOM 1964 C CD  . GLN A 1 336 ? 130.700 137.421 71.474  1.00 83.66  ? 280 GLN R CD  1 
ATOM 1965 O OE1 . GLN A 1 336 ? 131.195 136.760 70.562  1.00 83.66  ? 280 GLN R OE1 1 
ATOM 1966 N NE2 . GLN A 1 336 ? 129.391 137.607 71.594  1.00 83.66  ? 280 GLN R NE2 1 
ATOM 1967 N N   . VAL A 1 337 ? 133.666 134.474 75.157  1.00 79.93  ? 281 VAL R N   1 
ATOM 1968 C CA  . VAL A 1 337 ? 134.703 133.459 75.310  1.00 79.93  ? 281 VAL R CA  1 
ATOM 1969 C C   . VAL A 1 337 ? 134.317 132.193 74.557  1.00 79.93  ? 281 VAL R C   1 
ATOM 1970 O O   . VAL A 1 337 ? 135.148 131.579 73.879  1.00 79.93  ? 281 VAL R O   1 
ATOM 1971 C CB  . VAL A 1 337 ? 134.962 133.175 76.800  1.00 79.93  ? 281 VAL R CB  1 
ATOM 1972 C CG1 . VAL A 1 337 ? 135.985 132.066 76.958  1.00 79.93  ? 281 VAL R CG1 1 
ATOM 1973 C CG2 . VAL A 1 337 ? 135.432 134.433 77.504  1.00 79.93  ? 281 VAL R CG2 1 
ATOM 1974 N N   . ILE A 1 338 ? 133.059 131.783 74.666  1.00 82.05  ? 282 ILE R N   1 
ATOM 1975 C CA  . ILE A 1 338 ? 132.516 130.662 73.908  1.00 82.05  ? 282 ILE R CA  1 
ATOM 1976 C C   . ILE A 1 338 ? 131.555 131.218 72.870  1.00 82.05  ? 282 ILE R C   1 
ATOM 1977 O O   . ILE A 1 338 ? 130.696 132.050 73.186  1.00 82.05  ? 282 ILE R O   1 
ATOM 1978 C CB  . ILE A 1 338 ? 131.807 129.651 74.827  1.00 82.05  ? 282 ILE R CB  1 
ATOM 1979 C CG1 . ILE A 1 338 ? 132.765 129.137 75.900  1.00 82.05  ? 282 ILE R CG1 1 
ATOM 1980 C CG2 . ILE A 1 338 ? 131.264 128.490 74.012  1.00 82.05  ? 282 ILE R CG2 1 
ATOM 1981 C CD1 . ILE A 1 338 ? 132.076 128.364 77.000  1.00 82.05  ? 282 ILE R CD1 1 
ATOM 1982 N N   . GLN A 1 339 ? 131.694 130.763 71.630  1.00 90.70  ? 283 GLN R N   1 
ATOM 1983 C CA  . GLN A 1 339 ? 130.866 131.290 70.557  1.00 90.70  ? 283 GLN R CA  1 
ATOM 1984 C C   . GLN A 1 339 ? 129.391 131.066 70.872  1.00 90.70  ? 283 GLN R C   1 
ATOM 1985 O O   . GLN A 1 339 ? 129.004 130.054 71.462  1.00 90.70  ? 283 GLN R O   1 
ATOM 1986 C CB  . GLN A 1 339 ? 131.235 130.634 69.229  1.00 90.70  ? 283 GLN R CB  1 
ATOM 1987 C CG  . GLN A 1 339 ? 130.576 131.275 68.024  1.00 90.70  ? 283 GLN R CG  1 
ATOM 1988 C CD  . GLN A 1 339 ? 131.238 130.881 66.720  1.00 90.70  ? 283 GLN R CD  1 
ATOM 1989 O OE1 . GLN A 1 339 ? 132.350 130.353 66.709  1.00 90.70  ? 283 GLN R OE1 1 
ATOM 1990 N NE2 . GLN A 1 339 ? 130.557 131.139 65.610  1.00 90.70  ? 283 GLN R NE2 1 
ATOM 1991 N N   . GLU A 1 340 ? 128.566 132.030 70.474  1.00 92.62  ? 284 GLU R N   1 
ATOM 1992 C CA  . GLU A 1 340 ? 127.165 132.086 70.871  1.00 92.62  ? 284 GLU R CA  1 
ATOM 1993 C C   . GLU A 1 340 ? 126.265 131.713 69.700  1.00 92.62  ? 284 GLU R C   1 
ATOM 1994 O O   . GLU A 1 340 ? 126.489 132.161 68.571  1.00 92.62  ? 284 GLU R O   1 
ATOM 1995 C CB  . GLU A 1 340 ? 126.816 133.486 71.378  1.00 92.62  ? 284 GLU R CB  1 
ATOM 1996 C CG  . GLU A 1 340 ? 125.578 133.545 72.250  1.00 92.62  ? 284 GLU R CG  1 
ATOM 1997 C CD  . GLU A 1 340 ? 125.397 134.898 72.905  1.00 92.62  ? 284 GLU R CD  1 
ATOM 1998 O OE1 . GLU A 1 340 ? 126.228 135.795 72.653  1.00 92.62  ? 284 GLU R OE1 1 
ATOM 1999 O OE2 . GLU A 1 340 ? 124.424 135.067 73.669  1.00 92.62  ? 284 GLU R OE2 1 
ATOM 2000 N N   . THR A 1 341 ? 125.252 130.891 69.974  1.00 95.35  ? 285 THR R N   1 
ATOM 2001 C CA  . THR A 1 341 ? 124.254 130.519 68.980  1.00 95.35  ? 285 THR R CA  1 
ATOM 2002 C C   . THR A 1 341 ? 122.928 130.277 69.687  1.00 95.35  ? 285 THR R C   1 
ATOM 2003 O O   . THR A 1 341 ? 122.875 130.131 70.910  1.00 95.35  ? 285 THR R O   1 
ATOM 2004 C CB  . THR A 1 341 ? 124.665 129.272 68.188  1.00 95.35  ? 285 THR R CB  1 
ATOM 2005 O OG1 . THR A 1 341 ? 124.726 128.141 69.066  1.00 95.35  ? 285 THR R OG1 1 
ATOM 2006 C CG2 . THR A 1 341 ? 126.016 129.472 67.522  1.00 95.35  ? 285 THR R CG2 1 
ATOM 2007 N N   . CYS A 1 342 ? 121.850 130.239 68.902  1.00 104.15 ? 286 CYS R N   1 
ATOM 2008 C CA  . CYS A 1 342 ? 120.519 130.058 69.478  1.00 104.15 ? 286 CYS R CA  1 
ATOM 2009 C C   . CYS A 1 342 ? 120.432 128.741 70.244  1.00 104.15 ? 286 CYS R C   1 
ATOM 2010 O O   . CYS A 1 342 ? 119.919 128.687 71.370  1.00 104.15 ? 286 CYS R O   1 
ATOM 2011 C CB  . CYS A 1 342 ? 119.458 130.098 68.375  1.00 104.15 ? 286 CYS R CB  1 
ATOM 2012 S SG  . CYS A 1 342 ? 119.331 131.636 67.404  1.00 104.15 ? 286 CYS R SG  1 
ATOM 2013 N N   . GLU A 1 343 ? 120.934 127.660 69.642  1.00 99.35  ? 287 GLU R N   1 
ATOM 2014 C CA  . GLU A 1 343 ? 120.838 126.350 70.278  1.00 99.35  ? 287 GLU R CA  1 
ATOM 2015 C C   . GLU A 1 343 ? 121.616 126.316 71.585  1.00 99.35  ? 287 GLU R C   1 
ATOM 2016 O O   . GLU A 1 343 ? 121.175 125.700 72.562  1.00 99.35  ? 287 GLU R O   1 
ATOM 2017 C CB  . GLU A 1 343 ? 121.342 125.264 69.329  1.00 99.35  ? 287 GLU R CB  1 
ATOM 2018 C CG  . GLU A 1 343 ? 120.688 125.287 67.959  1.00 99.35  ? 287 GLU R CG  1 
ATOM 2019 C CD  . GLU A 1 343 ? 120.973 124.034 67.155  1.00 99.35  ? 287 GLU R CD  1 
ATOM 2020 O OE1 . GLU A 1 343 ? 121.623 123.113 67.693  1.00 99.35  ? 287 GLU R OE1 1 
ATOM 2021 O OE2 . GLU A 1 343 ? 120.546 123.969 65.983  1.00 99.35  ? 287 GLU R OE2 1 
ATOM 2022 N N   . ARG A 1 344 ? 122.784 126.956 71.620  1.00 90.70  ? 288 ARG R N   1 
ATOM 2023 C CA  . ARG A 1 344 ? 123.550 127.002 72.859  1.00 90.70  ? 288 ARG R CA  1 
ATOM 2024 C C   . ARG A 1 344 ? 122.783 127.751 73.941  1.00 90.70  ? 288 ARG R C   1 
ATOM 2025 O O   . ARG A 1 344 ? 122.807 127.360 75.115  1.00 90.70  ? 288 ARG R O   1 
ATOM 2026 C CB  . ARG A 1 344 ? 124.912 127.647 72.606  1.00 90.70  ? 288 ARG R CB  1 
ATOM 2027 C CG  . ARG A 1 344 ? 125.882 127.511 73.763  1.00 90.70  ? 288 ARG R CG  1 
ATOM 2028 C CD  . ARG A 1 344 ? 127.201 128.202 73.465  1.00 90.70  ? 288 ARG R CD  1 
ATOM 2029 N NE  . ARG A 1 344 ? 127.942 127.546 72.395  1.00 90.70  ? 288 ARG R NE  1 
ATOM 2030 C CZ  . ARG A 1 344 ? 128.519 126.357 72.499  1.00 90.70  ? 288 ARG R CZ  1 
ATOM 2031 N NH1 . ARG A 1 344 ? 128.473 125.662 73.624  1.00 90.70  ? 288 ARG R NH1 1 
ATOM 2032 N NH2 . ARG A 1 344 ? 129.163 125.854 71.450  1.00 90.70  ? 288 ARG R NH2 1 
ATOM 2033 N N   . ARG A 1 345 ? 122.091 128.828 73.566  1.00 91.76  ? 289 ARG R N   1 
ATOM 2034 C CA  . ARG A 1 345 ? 121.254 129.539 74.526  1.00 91.76  ? 289 ARG R CA  1 
ATOM 2035 C C   . ARG A 1 345 ? 120.162 128.630 75.069  1.00 91.76  ? 289 ARG R C   1 
ATOM 2036 O O   . ARG A 1 345 ? 119.899 128.611 76.277  1.00 91.76  ? 289 ARG R O   1 
ATOM 2037 C CB  . ARG A 1 345 ? 120.629 130.768 73.872  1.00 91.76  ? 289 ARG R CB  1 
ATOM 2038 C CG  . ARG A 1 345 ? 121.606 131.849 73.487  1.00 91.76  ? 289 ARG R CG  1 
ATOM 2039 C CD  . ARG A 1 345 ? 120.865 133.022 72.891  1.00 91.76  ? 289 ARG R CD  1 
ATOM 2040 N NE  . ARG A 1 345 ? 121.741 134.151 72.615  1.00 91.76  ? 289 ARG R NE  1 
ATOM 2041 C CZ  . ARG A 1 345 ? 121.317 135.341 72.217  1.00 91.76  ? 289 ARG R CZ  1 
ATOM 2042 N NH1 . ARG A 1 345 ? 120.029 135.595 72.053  1.00 91.76  ? 289 ARG R NH1 1 
ATOM 2043 N NH2 . ARG A 1 345 ? 122.206 136.300 71.980  1.00 91.76  ? 289 ARG R NH2 1 
ATOM 2044 N N   . ASN A 1 346 ? 119.501 127.880 74.185  1.00 94.05  ? 290 ASN R N   1 
ATOM 2045 C CA  . ASN A 1 346 ? 118.456 126.971 74.641  1.00 94.05  ? 290 ASN R CA  1 
ATOM 2046 C C   . ASN A 1 346 ? 119.022 125.936 75.601  1.00 94.05  ? 290 ASN R C   1 
ATOM 2047 O O   . ASN A 1 346 ? 118.407 125.618 76.628  1.00 94.05  ? 290 ASN R O   1 
ATOM 2048 C CB  . ASN A 1 346 ? 117.801 126.283 73.445  1.00 94.05  ? 290 ASN R CB  1 
ATOM 2049 C CG  . ASN A 1 346 ? 116.990 127.235 72.599  1.00 94.05  ? 290 ASN R CG  1 
ATOM 2050 O OD1 . ASN A 1 346 ? 116.560 128.287 73.067  1.00 94.05  ? 290 ASN R OD1 1 
ATOM 2051 N ND2 . ASN A 1 346 ? 116.771 126.868 71.343  1.00 94.05  ? 290 ASN R ND2 1 
ATOM 2052 N N   . HIS A 1 347 ? 120.196 125.395 75.275  1.00 86.13  ? 291 HIS R N   1 
ATOM 2053 C CA  . HIS A 1 347 ? 120.820 124.397 76.134  1.00 86.13  ? 291 HIS R CA  1 
ATOM 2054 C C   . HIS A 1 347 ? 121.124 124.978 77.506  1.00 86.13  ? 291 HIS R C   1 
ATOM 2055 O O   . HIS A 1 347 ? 120.869 124.341 78.534  1.00 86.13  ? 291 HIS R O   1 
ATOM 2056 C CB  . HIS A 1 347 ? 122.096 123.878 75.476  1.00 86.13  ? 291 HIS R CB  1 
ATOM 2057 C CG  . HIS A 1 347 ? 121.850 123.081 74.235  1.00 86.13  ? 291 HIS R CG  1 
ATOM 2058 N ND1 . HIS A 1 347 ? 122.866 122.658 73.408  1.00 86.13  ? 291 HIS R ND1 1 
ATOM 2059 C CD2 . HIS A 1 347 ? 120.700 122.632 73.680  1.00 86.13  ? 291 HIS R CD2 1 
ATOM 2060 C CE1 . HIS A 1 347 ? 122.354 121.982 72.396  1.00 86.13  ? 291 HIS R CE1 1 
ATOM 2061 N NE2 . HIS A 1 347 ? 121.041 121.951 72.537  1.00 86.13  ? 291 HIS R NE2 1 
ATOM 2062 N N   . ILE A 1 348 ? 121.664 126.197 77.543  1.00 79.40  ? 292 ILE R N   1 
ATOM 2063 C CA  . ILE A 1 348 ? 121.999 126.800 78.828  1.00 79.40  ? 292 ILE R CA  1 
ATOM 2064 C C   . ILE A 1 348 ? 120.740 127.102 79.627  1.00 79.40  ? 292 ILE R C   1 
ATOM 2065 O O   . ILE A 1 348 ? 120.736 126.966 80.853  1.00 79.40  ? 292 ILE R O   1 
ATOM 2066 C CB  . ILE A 1 348 ? 122.856 128.061 78.632  1.00 79.40  ? 292 ILE R CB  1 
ATOM 2067 C CG1 . ILE A 1 348 ? 124.237 127.680 78.099  1.00 79.40  ? 292 ILE R CG1 1 
ATOM 2068 C CG2 . ILE A 1 348 ? 122.987 128.807 79.947  1.00 79.40  ? 292 ILE R CG2 1 
ATOM 2069 C CD1 . ILE A 1 348 ? 125.090 128.858 77.707  1.00 79.40  ? 292 ILE R CD1 1 
ATOM 2070 N N   . ASP A 1 349 ? 119.656 127.514 78.967  1.00 85.81  ? 293 ASP R N   1 
ATOM 2071 C CA  . ASP A 1 349 ? 118.413 127.771 79.690  1.00 85.81  ? 293 ASP R CA  1 
ATOM 2072 C C   . ASP A 1 349 ? 117.853 126.489 80.298  1.00 85.81  ? 293 ASP R C   1 
ATOM 2073 O O   . ASP A 1 349 ? 117.448 126.465 81.471  1.00 85.81  ? 293 ASP R O   1 
ATOM 2074 C CB  . ASP A 1 349 ? 117.388 128.414 78.758  1.00 85.81  ? 293 ASP R CB  1 
ATOM 2075 C CG  . ASP A 1 349 ? 117.697 129.870 78.466  1.00 85.81  ? 293 ASP R CG  1 
ATOM 2076 O OD1 . ASP A 1 349 ? 118.754 130.358 78.916  1.00 85.81  ? 293 ASP R OD1 1 
ATOM 2077 O OD2 . ASP A 1 349 ? 116.881 130.530 77.787  1.00 85.81  ? 293 ASP R OD2 1 
ATOM 2078 N N   . ARG A 1 350 ? 117.821 125.408 79.515  1.00 84.13  ? 294 ARG R N   1 
ATOM 2079 C CA  . ARG A 1 350 ? 117.344 124.136 80.048  1.00 84.13  ? 294 ARG R CA  1 
ATOM 2080 C C   . ARG A 1 350 ? 118.218 123.671 81.205  1.00 84.13  ? 294 ARG R C   1 
ATOM 2081 O O   . ARG A 1 350 ? 117.712 123.185 82.226  1.00 84.13  ? 294 ARG R O   1 
ATOM 2082 C CB  . ARG A 1 350 ? 117.320 123.077 78.945  1.00 84.13  ? 294 ARG R CB  1 
ATOM 2083 C CG  . ARG A 1 350 ? 116.335 123.335 77.806  1.00 84.13  ? 294 ARG R CG  1 
ATOM 2084 C CD  . ARG A 1 350 ? 114.947 123.726 78.289  1.00 84.13  ? 294 ARG R CD  1 
ATOM 2085 N NE  . ARG A 1 350 ? 114.727 125.165 78.207  1.00 84.13  ? 294 ARG R NE  1 
ATOM 2086 C CZ  . ARG A 1 350 ? 113.744 125.810 78.818  1.00 84.13  ? 294 ARG R CZ  1 
ATOM 2087 N NH1 . ARG A 1 350 ? 112.858 125.174 79.567  1.00 84.13  ? 294 ARG R NH1 1 
ATOM 2088 N NH2 . ARG A 1 350 ? 113.646 127.129 78.675  1.00 84.13  ? 294 ARG R NH2 1 
ATOM 2089 N N   . ALA A 1 351 ? 119.536 123.811 81.062  1.00 72.27  ? 295 ALA R N   1 
ATOM 2090 C CA  . ALA A 1 351 ? 120.448 123.417 82.127  1.00 72.27  ? 295 ALA R CA  1 
ATOM 2091 C C   . ALA A 1 351 ? 120.197 124.237 83.383  1.00 72.27  ? 295 ALA R C   1 
ATOM 2092 O O   . ALA A 1 351 ? 120.221 123.711 84.498  1.00 72.27  ? 295 ALA R O   1 
ATOM 2093 C CB  . ALA A 1 351 ? 121.893 123.575 81.658  1.00 72.27  ? 295 ALA R CB  1 
ATOM 2094 N N   . LEU A 1 352 ? 119.964 125.541 83.221  1.00 74.28  ? 296 LEU R N   1 
ATOM 2095 C CA  . LEU A 1 352 ? 119.691 126.384 84.377  1.00 74.28  ? 296 LEU R CA  1 
ATOM 2096 C C   . LEU A 1 352 ? 118.430 125.934 85.094  1.00 74.28  ? 296 LEU R C   1 
ATOM 2097 O O   . LEU A 1 352 ? 118.404 125.846 86.326  1.00 74.28  ? 296 LEU R O   1 
ATOM 2098 C CB  . LEU A 1 352 ? 119.563 127.843 83.945  1.00 74.28  ? 296 LEU R CB  1 
ATOM 2099 C CG  . LEU A 1 352 ? 120.873 128.619 83.822  1.00 74.28  ? 296 LEU R CG  1 
ATOM 2100 C CD1 . LEU A 1 352 ? 120.619 129.966 83.179  1.00 74.28  ? 296 LEU R CD1 1 
ATOM 2101 C CD2 . LEU A 1 352 ? 121.530 128.790 85.178  1.00 74.28  ? 296 LEU R CD2 1 
ATOM 2102 N N   . ASP A 1 353 ? 117.373 125.636 84.340  1.00 78.23  ? 297 ASP R N   1 
ATOM 2103 C CA  . ASP A 1 353 ? 116.140 125.172 84.972  1.00 78.23  ? 297 ASP R CA  1 
ATOM 2104 C C   . ASP A 1 353 ? 116.373 123.876 85.743  1.00 78.23  ? 297 ASP R C   1 
ATOM 2105 O O   . ASP A 1 353 ? 116.001 123.756 86.923  1.00 78.23  ? 297 ASP R O   1 
ATOM 2106 C CB  . ASP A 1 353 ? 115.056 124.982 83.912  1.00 78.23  ? 297 ASP R CB  1 
ATOM 2107 C CG  . ASP A 1 353 ? 113.696 124.703 84.513  1.00 78.23  ? 297 ASP R CG  1 
ATOM 2108 O OD1 . ASP A 1 353 ? 113.587 124.673 85.757  1.00 78.23  ? 297 ASP R OD1 1 
ATOM 2109 O OD2 . ASP A 1 353 ? 112.733 124.512 83.741  1.00 78.23  ? 297 ASP R OD2 1 
ATOM 2110 N N   . ALA A 1 354 ? 117.005 122.896 85.094  1.00 70.05  ? 298 ALA R N   1 
ATOM 2111 C CA  . ALA A 1 354 ? 117.221 121.605 85.739  1.00 70.05  ? 298 ALA R CA  1 
ATOM 2112 C C   . ALA A 1 354 ? 118.080 121.755 86.987  1.00 70.05  ? 298 ALA R C   1 
ATOM 2113 O O   . ALA A 1 354 ? 117.792 121.160 88.031  1.00 70.05  ? 298 ALA R O   1 
ATOM 2114 C CB  . ALA A 1 354 ? 117.868 120.632 84.755  1.00 70.05  ? 298 ALA R CB  1 
ATOM 2115 N N   . THR A 1 355 ? 119.140 122.558 86.901  1.00 69.49  ? 299 THR R N   1 
ATOM 2116 C CA  . THR A 1 355 ? 120.051 122.699 88.027  1.00 69.49  ? 299 THR R CA  1 
ATOM 2117 C C   . THR A 1 355 ? 119.427 123.497 89.163  1.00 69.49  ? 299 THR R C   1 
ATOM 2118 O O   . THR A 1 355 ? 119.747 123.253 90.328  1.00 69.49  ? 299 THR R O   1 
ATOM 2119 C CB  . THR A 1 355 ? 121.349 123.350 87.563  1.00 69.49  ? 299 THR R CB  1 
ATOM 2120 O OG1 . THR A 1 355 ? 121.054 124.569 86.873  1.00 69.49  ? 299 THR R OG1 1 
ATOM 2121 C CG2 . THR A 1 355 ? 122.101 122.415 86.634  1.00 69.49  ? 299 THR R CG2 1 
ATOM 2122 N N   . GLU A 1 356 ? 118.540 124.447 88.860  1.00 74.40  ? 300 GLU R N   1 
ATOM 2123 C CA  . GLU A 1 356 ? 117.790 125.095 89.930  1.00 74.40  ? 300 GLU R CA  1 
ATOM 2124 C C   . GLU A 1 356 ? 116.916 124.087 90.662  1.00 74.40  ? 300 GLU R C   1 
ATOM 2125 O O   . GLU A 1 356 ? 116.876 124.068 91.901  1.00 74.40  ? 300 GLU R O   1 
ATOM 2126 C CB  . GLU A 1 356 ? 116.935 126.228 89.369  1.00 74.40  ? 300 GLU R CB  1 
ATOM 2127 C CG  . GLU A 1 356 ? 117.683 127.531 89.167  1.00 74.40  ? 300 GLU R CG  1 
ATOM 2128 C CD  . GLU A 1 356 ? 116.754 128.693 88.882  1.00 74.40  ? 300 GLU R CD  1 
ATOM 2129 O OE1 . GLU A 1 356 ? 115.527 128.472 88.821  1.00 74.40  ? 300 GLU R OE1 1 
ATOM 2130 O OE2 . GLU A 1 356 ? 117.249 129.828 88.719  1.00 74.40  ? 300 GLU R OE2 1 
ATOM 2131 N N   . ILE A 1 357 ? 116.218 123.230 89.912  1.00 73.51  ? 301 ILE R N   1 
ATOM 2132 C CA  . ILE A 1 357 ? 115.425 122.190 90.564  1.00 73.51  ? 301 ILE R CA  1 
ATOM 2133 C C   . ILE A 1 357 ? 116.319 121.327 91.442  1.00 73.51  ? 301 ILE R C   1 
ATOM 2134 O O   . ILE A 1 357 ? 115.972 121.005 92.584  1.00 73.51  ? 301 ILE R O   1 
ATOM 2135 C CB  . ILE A 1 357 ? 114.677 121.342 89.521  1.00 73.51  ? 301 ILE R CB  1 
ATOM 2136 C CG1 . ILE A 1 357 ? 113.619 122.180 88.806  1.00 73.51  ? 301 ILE R CG1 1 
ATOM 2137 C CG2 . ILE A 1 357 ? 114.027 120.142 90.184  1.00 73.51  ? 301 ILE R CG2 1 
ATOM 2138 C CD1 . ILE A 1 357 ? 113.200 121.606 87.472  1.00 73.51  ? 301 ILE R CD1 1 
ATOM 2139 N N   . LEU A 1 358 ? 117.485 120.945 90.925  1.00 71.23  ? 302 LEU R N   1 
ATOM 2140 C CA  . LEU A 1 358 ? 118.388 120.085 91.683  1.00 71.23  ? 302 LEU R CA  1 
ATOM 2141 C C   . LEU A 1 358 ? 118.866 120.764 92.960  1.00 71.23  ? 302 LEU R C   1 
ATOM 2142 O O   . LEU A 1 358 ? 118.908 120.139 94.025  1.00 71.23  ? 302 LEU R O   1 
ATOM 2143 C CB  . LEU A 1 358 ? 119.579 119.692 90.811  1.00 71.23  ? 302 LEU R CB  1 
ATOM 2144 C CG  . LEU A 1 358 ? 120.505 118.609 91.356  1.00 71.23  ? 302 LEU R CG  1 
ATOM 2145 C CD1 . LEU A 1 358 ? 119.735 117.338 91.651  1.00 71.23  ? 302 LEU R CD1 1 
ATOM 2146 C CD2 . LEU A 1 358 ? 121.618 118.339 90.363  1.00 71.23  ? 302 LEU R CD2 1 
ATOM 2147 N N   . GLY A 1 359 ? 119.232 122.042 92.875  1.00 70.96  ? 303 GLY R N   1 
ATOM 2148 C CA  . GLY A 1 359 ? 119.758 122.729 94.042  1.00 70.96  ? 303 GLY R CA  1 
ATOM 2149 C C   . GLY A 1 359 ? 118.695 123.013 95.085  1.00 70.96  ? 303 GLY R C   1 
ATOM 2150 O O   . GLY A 1 359 ? 119.001 123.161 96.270  1.00 70.96  ? 303 GLY R O   1 
ATOM 2151 N N   . ILE A 1 360 ? 117.432 123.092 94.663  1.00 69.84  ? 304 ILE R N   1 
ATOM 2152 C CA  . ILE A 1 360 ? 116.356 123.360 95.612  1.00 69.84  ? 304 ILE R CA  1 
ATOM 2153 C C   . ILE A 1 360 ? 116.171 122.224 96.616  1.00 69.84  ? 304 ILE R C   1 
ATOM 2154 O O   . ILE A 1 360 ? 115.467 122.393 97.616  1.00 69.84  ? 304 ILE R O   1 
ATOM 2155 C CB  . ILE A 1 360 ? 115.062 123.661 94.823  1.00 69.84  ? 304 ILE R CB  1 
ATOM 2156 C CG1 . ILE A 1 360 ? 115.038 125.140 94.443  1.00 69.84  ? 304 ILE R CG1 1 
ATOM 2157 C CG2 . ILE A 1 360 ? 113.817 123.291 95.607  1.00 69.84  ? 304 ILE R CG2 1 
ATOM 2158 C CD1 . ILE A 1 360 ? 113.963 125.500 93.462  1.00 69.84  ? 304 ILE R CD1 1 
ATOM 2159 N N   . LEU A 1 361 ? 116.809 121.074 96.397  1.00 69.49  ? 305 LEU R N   1 
ATOM 2160 C CA  . LEU A 1 361 ? 116.643 119.925 97.280  1.00 69.49  ? 305 LEU R CA  1 
ATOM 2161 C C   . LEU A 1 361 ? 117.494 119.998 98.541  1.00 69.49  ? 305 LEU R C   1 
ATOM 2162 O O   . LEU A 1 361 ? 117.400 119.095 99.380  1.00 69.49  ? 305 LEU R O   1 
ATOM 2163 C CB  . LEU A 1 361 ? 116.977 118.633 96.531  1.00 69.49  ? 305 LEU R CB  1 
ATOM 2164 C CG  . LEU A 1 361 ? 116.244 118.391 95.215  1.00 69.49  ? 305 LEU R CG  1 
ATOM 2165 C CD1 . LEU A 1 361 ? 116.608 117.031 94.651  1.00 69.49  ? 305 LEU R CD1 1 
ATOM 2166 C CD2 . LEU A 1 361 ? 114.747 118.501 95.412  1.00 69.49  ? 305 LEU R CD2 1 
ATOM 2167 N N   . HIS A 1 362 ? 118.333 121.023 98.693  1.00 69.49  ? 306 HIS R N   1 
ATOM 2168 C CA  . HIS A 1 362 ? 119.159 121.113 99.891  1.00 69.49  ? 306 HIS R CA  1 
ATOM 2169 C C   . HIS A 1 362 ? 118.298 121.273 101.137 1.00 69.49  ? 306 HIS R C   1 
ATOM 2170 O O   . HIS A 1 362 ? 118.614 120.719 102.194 1.00 69.49  ? 306 HIS R O   1 
ATOM 2171 C CB  . HIS A 1 362 ? 120.153 122.267 99.761  1.00 69.49  ? 306 HIS R CB  1 
ATOM 2172 C CG  . HIS A 1 362 ? 119.533 123.623 99.895  1.00 69.49  ? 306 HIS R CG  1 
ATOM 2173 N ND1 . HIS A 1 362 ? 119.130 124.141 101.106 1.00 69.49  ? 306 HIS R ND1 1 
ATOM 2174 C CD2 . HIS A 1 362 ? 119.248 124.568 98.969  1.00 69.49  ? 306 HIS R CD2 1 
ATOM 2175 C CE1 . HIS A 1 362 ? 118.623 125.347 100.921 1.00 69.49  ? 306 HIS R CE1 1 
ATOM 2176 N NE2 . HIS A 1 362 ? 118.684 125.629 99.633  1.00 69.49  ? 306 HIS R NE2 1 
ATOM 2177 N N   . SER A 1 363 ? 117.203 122.027 101.033 1.00 69.49  ? 307 SER R N   1 
ATOM 2178 C CA  . SER A 1 363 ? 116.324 122.208 102.183 1.00 69.49  ? 307 SER R CA  1 
ATOM 2179 C C   . SER A 1 363 ? 115.714 120.884 102.619 1.00 69.49  ? 307 SER R C   1 
ATOM 2180 O O   . SER A 1 363 ? 115.522 120.645 103.816 1.00 69.49  ? 307 SER R O   1 
ATOM 2181 C CB  . SER A 1 363 ? 115.228 123.219 101.851 1.00 69.49  ? 307 SER R CB  1 
ATOM 2182 O OG  . SER A 1 363 ? 114.837 123.119 100.495 1.00 69.49  ? 307 SER R OG  1 
ATOM 2183 N N   . CYS A 1 364 ? 115.389 120.016 101.660 1.00 69.49  ? 308 CYS R N   1 
ATOM 2184 C CA  . CYS A 1 364 ? 114.838 118.710 102.003 1.00 69.49  ? 308 CYS R CA  1 
ATOM 2185 C C   . CYS A 1 364 ? 115.906 117.784 102.568 1.00 69.49  ? 308 CYS R C   1 
ATOM 2186 O O   . CYS A 1 364 ? 115.636 117.008 103.490 1.00 69.49  ? 308 CYS R O   1 
ATOM 2187 C CB  . CYS A 1 364 ? 114.192 118.075 100.776 1.00 69.49  ? 308 CYS R CB  1 
ATOM 2188 S SG  . CYS A 1 364 ? 112.618 118.797 100.324 1.00 69.49  ? 308 CYS R SG  1 
ATOM 2189 N N   . LEU A 1 365 ? 117.119 117.840 102.023 1.00 69.49  ? 309 LEU R N   1 
ATOM 2190 C CA  . LEU A 1 365 ? 118.143 116.867 102.379 1.00 69.49  ? 309 LEU R CA  1 
ATOM 2191 C C   . LEU A 1 365 ? 118.947 117.244 103.617 1.00 69.49  ? 309 LEU R C   1 
ATOM 2192 O O   . LEU A 1 365 ? 119.605 116.371 104.193 1.00 69.49  ? 309 LEU R O   1 
ATOM 2193 C CB  . LEU A 1 365 ? 119.103 116.666 101.204 1.00 69.49  ? 309 LEU R CB  1 
ATOM 2194 C CG  . LEU A 1 365 ? 118.486 116.073 99.939  1.00 69.49  ? 309 LEU R CG  1 
ATOM 2195 C CD1 . LEU A 1 365 ? 119.439 116.218 98.774  1.00 69.49  ? 309 LEU R CD1 1 
ATOM 2196 C CD2 . LEU A 1 365 ? 118.127 114.618 100.148 1.00 69.49  ? 309 LEU R CD2 1 
ATOM 2197 N N   . ASN A 1 366 ? 118.923 118.506 104.038 1.00 69.49  ? 310 ASN R N   1 
ATOM 2198 C CA  . ASN A 1 366 ? 119.702 118.927 105.197 1.00 69.49  ? 310 ASN R CA  1 
ATOM 2199 C C   . ASN A 1 366 ? 119.216 118.248 106.473 1.00 69.49  ? 310 ASN R C   1 
ATOM 2200 O O   . ASN A 1 366 ? 120.036 117.751 107.256 1.00 69.49  ? 310 ASN R O   1 
ATOM 2201 C CB  . ASN A 1 366 ? 119.643 120.448 105.350 1.00 69.49  ? 310 ASN R CB  1 
ATOM 2202 C CG  . ASN A 1 366 ? 120.706 121.158 104.537 1.00 69.49  ? 310 ASN R CG  1 
ATOM 2203 O OD1 . ASN A 1 366 ? 121.518 120.526 103.865 1.00 69.49  ? 310 ASN R OD1 1 
ATOM 2204 N ND2 . ASN A 1 366 ? 120.698 122.482 104.587 1.00 69.49  ? 310 ASN R ND2 1 
ATOM 2205 N N   . PRO A 1 367 ? 117.908 118.219 106.736 1.00 69.49  ? 311 PRO R N   1 
ATOM 2206 C CA  . PRO A 1 367 ? 117.435 117.566 107.966 1.00 69.49  ? 311 PRO R CA  1 
ATOM 2207 C C   . PRO A 1 367 ? 117.828 116.107 108.070 1.00 69.49  ? 311 PRO R C   1 
ATOM 2208 O O   . PRO A 1 367 ? 118.087 115.625 109.177 1.00 69.49  ? 311 PRO R O   1 
ATOM 2209 C CB  . PRO A 1 367 ? 115.914 117.734 107.882 1.00 69.49  ? 311 PRO R CB  1 
ATOM 2210 C CG  . PRO A 1 367 ? 115.726 118.932 107.055 1.00 69.49  ? 311 PRO R CG  1 
ATOM 2211 C CD  . PRO A 1 367 ? 116.803 118.879 106.024 1.00 69.49  ? 311 PRO R CD  1 
ATOM 2212 N N   . LEU A 1 368 ? 117.869 115.382 106.955 1.00 69.49  ? 312 LEU R N   1 
ATOM 2213 C CA  . LEU A 1 368 ? 118.230 113.971 107.010 1.00 69.49  ? 312 LEU R CA  1 
ATOM 2214 C C   . LEU A 1 368 ? 119.723 113.783 107.234 1.00 69.49  ? 312 LEU R C   1 
ATOM 2215 O O   . LEU A 1 368 ? 120.140 112.809 107.867 1.00 69.49  ? 312 LEU R O   1 
ATOM 2216 C CB  . LEU A 1 368 ? 117.804 113.269 105.721 1.00 69.49  ? 312 LEU R CB  1 
ATOM 2217 C CG  . LEU A 1 368 ? 116.404 113.593 105.206 1.00 69.49  ? 312 LEU R CG  1 
ATOM 2218 C CD1 . LEU A 1 368 ? 116.073 112.719 104.012 1.00 69.49  ? 312 LEU R CD1 1 
ATOM 2219 C CD2 . LEU A 1 368 ? 115.378 113.409 106.305 1.00 69.49  ? 312 LEU R CD2 1 
ATOM 2220 N N   . ILE A 1 369 ? 120.541 114.701 106.722 1.00 69.49  ? 313 ILE R N   1 
ATOM 2221 C CA  . ILE A 1 369 ? 121.985 114.503 106.746 1.00 69.49  ? 313 ILE R CA  1 
ATOM 2222 C C   . ILE A 1 369 ? 122.588 115.011 108.046 1.00 69.49  ? 313 ILE R C   1 
ATOM 2223 O O   . ILE A 1 369 ? 123.494 114.385 108.603 1.00 69.49  ? 313 ILE R O   1 
ATOM 2224 C CB  . ILE A 1 369 ? 122.629 115.185 105.530 1.00 69.49  ? 313 ILE R CB  1 
ATOM 2225 C CG1 . ILE A 1 369 ? 122.139 114.542 104.237 1.00 69.49  ? 313 ILE R CG1 1 
ATOM 2226 C CG2 . ILE A 1 369 ? 124.132 115.092 105.620 1.00 69.49  ? 313 ILE R CG2 1 
ATOM 2227 C CD1 . ILE A 1 369 ? 122.365 115.403 103.031 1.00 69.49  ? 313 ILE R CD1 1 
ATOM 2228 N N   . TYR A 1 370 ? 122.123 116.153 108.542 1.00 69.49  ? 314 TYR R N   1 
ATOM 2229 C CA  . TYR A 1 370 ? 122.751 116.781 109.695 1.00 69.49  ? 314 TYR R CA  1 
ATOM 2230 C C   . TYR A 1 370 ? 122.033 116.508 111.006 1.00 69.49  ? 314 TYR R C   1 
ATOM 2231 O O   . TYR A 1 370 ? 122.683 116.475 112.054 1.00 69.49  ? 314 TYR R O   1 
ATOM 2232 C CB  . TYR A 1 370 ? 122.840 118.295 109.487 1.00 69.49  ? 314 TYR R CB  1 
ATOM 2233 C CG  . TYR A 1 370 ? 123.850 118.707 108.447 1.00 69.49  ? 314 TYR R CG  1 
ATOM 2234 C CD1 . TYR A 1 370 ? 125.186 118.850 108.771 1.00 69.49  ? 314 TYR R CD1 1 
ATOM 2235 C CD2 . TYR A 1 370 ? 123.465 118.951 107.142 1.00 69.49  ? 314 TYR R CD2 1 
ATOM 2236 C CE1 . TYR A 1 370 ? 126.107 119.225 107.827 1.00 69.49  ? 314 TYR R CE1 1 
ATOM 2237 C CE2 . TYR A 1 370 ? 124.379 119.326 106.191 1.00 69.49  ? 314 TYR R CE2 1 
ATOM 2238 C CZ  . TYR A 1 370 ? 125.698 119.461 106.538 1.00 69.49  ? 314 TYR R CZ  1 
ATOM 2239 O OH  . TYR A 1 370 ? 126.615 119.837 105.587 1.00 69.49  ? 314 TYR R OH  1 
ATOM 2240 N N   . ALA A 1 371 ? 120.719 116.304 110.981 1.00 69.49  ? 315 ALA R N   1 
ATOM 2241 C CA  . ALA A 1 371 ? 119.932 116.183 112.200 1.00 69.49  ? 315 ALA R CA  1 
ATOM 2242 C C   . ALA A 1 371 ? 119.573 114.739 112.520 1.00 69.49  ? 315 ALA R C   1 
ATOM 2243 O O   . ALA A 1 371 ? 119.884 114.255 113.609 1.00 69.49  ? 315 ALA R O   1 
ATOM 2244 C CB  . ALA A 1 371 ? 118.662 117.032 112.082 1.00 69.49  ? 315 ALA R CB  1 
ATOM 2245 N N   . PHE A 1 372 ? 118.931 114.029 111.596 1.00 69.49  ? 316 PHE R N   1 
ATOM 2246 C CA  . PHE A 1 372 ? 118.401 112.710 111.914 1.00 69.49  ? 316 PHE R CA  1 
ATOM 2247 C C   . PHE A 1 372 ? 119.392 111.588 111.646 1.00 69.49  ? 316 PHE R C   1 
ATOM 2248 O O   . PHE A 1 372 ? 119.028 110.420 111.806 1.00 69.49  ? 316 PHE R O   1 
ATOM 2249 C CB  . PHE A 1 372 ? 117.111 112.472 111.131 1.00 69.49  ? 316 PHE R CB  1 
ATOM 2250 C CG  . PHE A 1 372 ? 115.980 113.364 111.556 1.00 69.49  ? 316 PHE R CG  1 
ATOM 2251 C CD1 . PHE A 1 372 ? 115.558 113.388 112.875 1.00 69.49  ? 316 PHE R CD1 1 
ATOM 2252 C CD2 . PHE A 1 372 ? 115.352 114.189 110.644 1.00 69.49  ? 316 PHE R CD2 1 
ATOM 2253 C CE1 . PHE A 1 372 ? 114.529 114.211 113.274 1.00 69.49  ? 316 PHE R CE1 1 
ATOM 2254 C CE2 . PHE A 1 372 ? 114.320 115.014 111.037 1.00 69.49  ? 316 PHE R CE2 1 
ATOM 2255 C CZ  . PHE A 1 372 ? 113.908 115.024 112.354 1.00 69.49  ? 316 PHE R CZ  1 
ATOM 2256 N N   . ILE A 1 373 ? 120.626 111.905 111.245 1.00 69.49  ? 317 ILE R N   1 
ATOM 2257 C CA  . ILE A 1 373 ? 121.656 110.879 111.096 1.00 69.49  ? 317 ILE R CA  1 
ATOM 2258 C C   . ILE A 1 373 ? 122.359 110.565 112.404 1.00 69.49  ? 317 ILE R C   1 
ATOM 2259 O O   . ILE A 1 373 ? 123.231 109.688 112.429 1.00 69.49  ? 317 ILE R O   1 
ATOM 2260 C CB  . ILE A 1 373 ? 122.702 111.305 110.048 1.00 69.49  ? 317 ILE R CB  1 
ATOM 2261 C CG1 . ILE A 1 373 ? 123.375 110.078 109.434 1.00 69.49  ? 317 ILE R CG1 1 
ATOM 2262 C CG2 . ILE A 1 373 ? 123.740 112.220 110.671 1.00 69.49  ? 317 ILE R CG2 1 
ATOM 2263 C CD1 . ILE A 1 373 ? 123.823 110.287 108.010 1.00 69.49  ? 317 ILE R CD1 1 
ATOM 2264 N N   . GLY A 1 374 ? 122.011 111.251 113.486 1.00 69.49  ? 318 GLY R N   1 
ATOM 2265 C CA  . GLY A 1 374 ? 122.626 111.040 114.789 1.00 69.49  ? 318 GLY R CA  1 
ATOM 2266 C C   . GLY A 1 374 ? 121.615 110.449 115.757 1.00 69.49  ? 318 GLY R C   1 
ATOM 2267 O O   . GLY A 1 374 ? 120.419 110.717 115.653 1.00 69.49  ? 318 GLY R O   1 
ATOM 2268 N N   . GLN A 1 375 ? 122.110 109.646 116.700 1.00 63.86  ? 319 GLN R N   1 
ATOM 2269 C CA  . GLN A 1 375 ? 121.215 108.940 117.609 1.00 63.86  ? 319 GLN R CA  1 
ATOM 2270 C C   . GLN A 1 375 ? 120.479 109.893 118.537 1.00 63.86  ? 319 GLN R C   1 
ATOM 2271 O O   . GLN A 1 375 ? 119.338 109.618 118.922 1.00 63.86  ? 319 GLN R O   1 
ATOM 2272 C CB  . GLN A 1 375 ? 121.998 107.919 118.428 1.00 63.86  ? 319 GLN R CB  1 
ATOM 2273 C CG  . GLN A 1 375 ? 121.116 106.955 119.196 1.00 63.86  ? 319 GLN R CG  1 
ATOM 2274 C CD  . GLN A 1 375 ? 121.897 105.816 119.810 1.00 63.86  ? 319 GLN R CD  1 
ATOM 2275 O OE1 . GLN A 1 375 ? 123.124 105.863 119.889 1.00 63.86  ? 319 GLN R OE1 1 
ATOM 2276 N NE2 . GLN A 1 375 ? 121.190 104.781 120.245 1.00 63.86  ? 319 GLN R NE2 1 
ATOM 2277 N N   . LYS A 1 376 ? 121.110 111.004 118.916 1.00 69.49  ? 320 LYS R N   1 
ATOM 2278 C CA  . LYS A 1 376 ? 120.482 111.925 119.858 1.00 69.49  ? 320 LYS R CA  1 
ATOM 2279 C C   . LYS A 1 376 ? 119.154 112.438 119.318 1.00 69.49  ? 320 LYS R C   1 
ATOM 2280 O O   . LYS A 1 376 ? 118.136 112.420 120.019 1.00 69.49  ? 320 LYS R O   1 
ATOM 2281 C CB  . LYS A 1 376 ? 121.428 113.087 120.154 1.00 69.49  ? 320 LYS R CB  1 
ATOM 2282 C CG  . LYS A 1 376 ? 120.864 114.124 121.118 1.00 69.49  ? 320 LYS R CG  1 
ATOM 2283 C CD  . LYS A 1 376 ? 121.879 115.214 121.454 1.00 69.49  ? 320 LYS R CD  1 
ATOM 2284 C CE  . LYS A 1 376 ? 123.081 114.672 122.219 1.00 69.49  ? 320 LYS R CE  1 
ATOM 2285 N NZ  . LYS A 1 376 ? 124.068 115.741 122.545 1.00 69.49  ? 320 LYS R NZ  1 
ATOM 2286 N N   . PHE A 1 377 ? 119.145 112.899 118.067 1.00 69.49  ? 321 PHE R N   1 
ATOM 2287 C CA  . PHE A 1 377 ? 117.923 113.461 117.502 1.00 69.49  ? 321 PHE R CA  1 
ATOM 2288 C C   . PHE A 1 377 ? 116.843 112.406 117.344 1.00 69.49  ? 321 PHE R C   1 
ATOM 2289 O O   . PHE A 1 377 ? 115.666 112.680 117.590 1.00 69.49  ? 321 PHE R O   1 
ATOM 2290 C CB  . PHE A 1 377 ? 118.213 114.121 116.162 1.00 69.49  ? 321 PHE R CB  1 
ATOM 2291 C CG  . PHE A 1 377 ? 118.554 115.568 116.278 1.00 69.49  ? 321 PHE R CG  1 
ATOM 2292 C CD1 . PHE A 1 377 ? 119.685 115.969 116.964 1.00 69.49  ? 321 PHE R CD1 1 
ATOM 2293 C CD2 . PHE A 1 377 ? 117.732 116.529 115.726 1.00 69.49  ? 321 PHE R CD2 1 
ATOM 2294 C CE1 . PHE A 1 377 ? 119.999 117.301 117.082 1.00 69.49  ? 321 PHE R CE1 1 
ATOM 2295 C CE2 . PHE A 1 377 ? 118.041 117.860 115.842 1.00 69.49  ? 321 PHE R CE2 1 
ATOM 2296 C CZ  . PHE A 1 377 ? 119.177 118.248 116.521 1.00 69.49  ? 321 PHE R CZ  1 
ATOM 2297 N N   . ARG A 1 378 ? 117.210 111.203 116.911 1.00 69.49  ? 322 ARG R N   1 
ATOM 2298 C CA  . ARG A 1 378 ? 116.206 110.159 116.756 1.00 69.49  ? 322 ARG R CA  1 
ATOM 2299 C C   . ARG A 1 378 ? 115.596 109.784 118.099 1.00 69.49  ? 322 ARG R C   1 
ATOM 2300 O O   . ARG A 1 378 ? 114.373 109.621 118.210 1.00 69.49  ? 322 ARG R O   1 
ATOM 2301 C CB  . ARG A 1 378 ? 116.825 108.939 116.086 1.00 69.49  ? 322 ARG R CB  1 
ATOM 2302 C CG  . ARG A 1 378 ? 116.878 109.038 114.578 1.00 69.49  ? 322 ARG R CG  1 
ATOM 2303 C CD  . ARG A 1 378 ? 117.474 107.791 113.980 1.00 69.49  ? 322 ARG R CD  1 
ATOM 2304 N NE  . ARG A 1 378 ? 118.930 107.840 113.963 1.00 69.49  ? 322 ARG R NE  1 
ATOM 2305 C CZ  . ARG A 1 378 ? 119.727 106.871 114.391 1.00 69.49  ? 322 ARG R CZ  1 
ATOM 2306 N NH1 . ARG A 1 378 ? 119.246 105.753 114.911 1.00 69.49  ? 322 ARG R NH1 1 
ATOM 2307 N NH2 . ARG A 1 378 ? 121.043 107.026 114.294 1.00 69.49  ? 322 ARG R NH2 1 
ATOM 2308 N N   . HIS A 1 379 ? 116.429 109.647 119.133 1.00 78.21  ? 323 HIS R N   1 
ATOM 2309 C CA  . HIS A 1 379 ? 115.900 109.356 120.460 1.00 78.21  ? 323 HIS R CA  1 
ATOM 2310 C C   . HIS A 1 379 ? 114.980 110.470 120.935 1.00 78.21  ? 323 HIS R C   1 
ATOM 2311 O O   . HIS A 1 379 ? 113.900 110.206 121.478 1.00 78.21  ? 323 HIS R O   1 
ATOM 2312 C CB  . HIS A 1 379 ? 117.040 109.154 121.454 1.00 78.21  ? 323 HIS R CB  1 
ATOM 2313 C CG  . HIS A 1 379 ? 116.580 108.752 122.821 1.00 78.21  ? 323 HIS R CG  1 
ATOM 2314 N ND1 . HIS A 1 379 ? 115.994 107.532 123.080 1.00 78.21  ? 323 HIS R ND1 1 
ATOM 2315 C CD2 . HIS A 1 379 ? 116.603 109.416 124.000 1.00 78.21  ? 323 HIS R CD2 1 
ATOM 2316 C CE1 . HIS A 1 379 ? 115.687 107.457 124.362 1.00 78.21  ? 323 HIS R CE1 1 
ATOM 2317 N NE2 . HIS A 1 379 ? 116.045 108.588 124.943 1.00 78.21  ? 323 HIS R NE2 1 
ATOM 2318 N N   . GLY A 1 380 ? 115.385 111.725 120.737 1.00 69.49  ? 324 GLY R N   1 
ATOM 2319 C CA  . GLY A 1 380 ? 114.517 112.828 121.106 1.00 69.49  ? 324 GLY R CA  1 
ATOM 2320 C C   . GLY A 1 380 ? 113.186 112.778 120.385 1.00 69.49  ? 324 GLY R C   1 
ATOM 2321 O O   . GLY A 1 380 ? 112.130 112.917 121.002 1.00 69.49  ? 324 GLY R O   1 
ATOM 2322 N N   . LEU A 1 381 ? 113.218 112.561 119.071 1.00 69.49  ? 325 LEU R N   1 
ATOM 2323 C CA  . LEU A 1 381 ? 111.986 112.521 118.293 1.00 69.49  ? 325 LEU R CA  1 
ATOM 2324 C C   . LEU A 1 381 ? 111.067 111.419 118.786 1.00 69.49  ? 325 LEU R C   1 
ATOM 2325 O O   . LEU A 1 381 ? 109.852 111.617 118.892 1.00 69.49  ? 325 LEU R O   1 
ATOM 2326 C CB  . LEU A 1 381 ? 112.308 112.322 116.813 1.00 69.49  ? 325 LEU R CB  1 
ATOM 2327 C CG  . LEU A 1 381 ? 111.107 112.316 115.869 1.00 69.49  ? 325 LEU R CG  1 
ATOM 2328 C CD1 . LEU A 1 381 ? 110.523 113.706 115.738 1.00 69.49  ? 325 LEU R CD1 1 
ATOM 2329 C CD2 . LEU A 1 381 ? 111.510 111.779 114.515 1.00 69.49  ? 325 LEU R CD2 1 
ATOM 2330 N N   . LEU A 1 382 ? 111.624 110.247 119.086 1.00 71.29  ? 326 LEU R N   1 
ATOM 2331 C CA  . LEU A 1 382 ? 110.802 109.176 119.637 1.00 71.29  ? 326 LEU R CA  1 
ATOM 2332 C C   . LEU A 1 382 ? 110.219 109.579 120.985 1.00 71.29  ? 326 LEU R C   1 
ATOM 2333 O O   . LEU A 1 382 ? 109.059 109.271 121.284 1.00 71.29  ? 326 LEU R O   1 
ATOM 2334 C CB  . LEU A 1 382 ? 111.626 107.896 119.760 1.00 71.29  ? 326 LEU R CB  1 
ATOM 2335 C CG  . LEU A 1 382 ? 112.026 107.255 118.430 1.00 71.29  ? 326 LEU R CG  1 
ATOM 2336 C CD1 . LEU A 1 382 ? 112.835 106.001 118.666 1.00 71.29  ? 326 LEU R CD1 1 
ATOM 2337 C CD2 . LEU A 1 382 ? 110.804 106.938 117.595 1.00 71.29  ? 326 LEU R CD2 1 
ATOM 2338 N N   . LYS A 1 383 ? 111.002 110.280 121.805 1.00 81.17  ? 327 LYS R N   1 
ATOM 2339 C CA  . LYS A 1 383 ? 110.509 110.723 123.105 1.00 81.17  ? 327 LYS R CA  1 
ATOM 2340 C C   . LYS A 1 383 ? 109.325 111.675 122.953 1.00 81.17  ? 327 LYS R C   1 
ATOM 2341 O O   . LYS A 1 383 ? 108.320 111.552 123.661 1.00 81.17  ? 327 LYS R O   1 
ATOM 2342 C CB  . LYS A 1 383 ? 111.641 111.392 123.884 1.00 81.17  ? 327 LYS R CB  1 
ATOM 2343 C CG  . LYS A 1 383 ? 111.289 111.740 125.322 1.00 81.17  ? 327 LYS R CG  1 
ATOM 2344 C CD  . LYS A 1 383 ? 112.360 112.601 125.980 1.00 81.17  ? 327 LYS R CD  1 
ATOM 2345 C CE  . LYS A 1 383 ? 113.751 111.999 125.843 1.00 81.17  ? 327 LYS R CE  1 
ATOM 2346 N NZ  . LYS A 1 383 ? 113.787 110.564 126.234 1.00 81.17  ? 327 LYS R NZ  1 
ATOM 2347 N N   . ILE A 1 384 ? 109.427 112.632 122.027 1.00 69.58  ? 328 ILE R N   1 
ATOM 2348 C CA  . ILE A 1 384 ? 108.382 113.645 121.888 1.00 69.58  ? 328 ILE R CA  1 
ATOM 2349 C C   . ILE A 1 384 ? 107.070 113.003 121.463 1.00 69.58  ? 328 ILE R C   1 
ATOM 2350 O O   . ILE A 1 384 ? 105.994 113.379 121.940 1.00 69.58  ? 328 ILE R O   1 
ATOM 2351 C CB  . ILE A 1 384 ? 108.814 114.737 120.890 1.00 69.58  ? 328 ILE R CB  1 
ATOM 2352 C CG1 . ILE A 1 384 ? 110.122 115.398 121.322 1.00 69.58  ? 328 ILE R CG1 1 
ATOM 2353 C CG2 . ILE A 1 384 ? 107.737 115.787 120.763 1.00 69.58  ? 328 ILE R CG2 1 
ATOM 2354 C CD1 . ILE A 1 384 ? 110.211 115.692 122.789 1.00 69.58  ? 328 ILE R CD1 1 
ATOM 2355 N N   . LEU A 1 385 ? 107.134 112.024 120.560 1.00 78.98  ? 329 LEU R N   1 
ATOM 2356 C CA  . LEU A 1 385 ? 105.917 111.457 119.993 1.00 78.98  ? 329 LEU R CA  1 
ATOM 2357 C C   . LEU A 1 385 ? 104.992 110.884 121.059 1.00 78.98  ? 329 LEU R C   1 
ATOM 2358 O O   . LEU A 1 385 ? 103.781 110.803 120.830 1.00 78.98  ? 329 LEU R O   1 
ATOM 2359 C CB  . LEU A 1 385 ? 106.272 110.369 118.979 1.00 78.98  ? 329 LEU R CB  1 
ATOM 2360 C CG  . LEU A 1 385 ? 106.893 110.834 117.661 1.00 78.98  ? 329 LEU R CG  1 
ATOM 2361 C CD1 . LEU A 1 385 ? 107.248 109.634 116.803 1.00 78.98  ? 329 LEU R CD1 1 
ATOM 2362 C CD2 . LEU A 1 385 ? 105.964 111.769 116.908 1.00 78.98  ? 329 LEU R CD2 1 
ATOM 2363 N N   . ALA A 1 386 ? 105.527 110.488 122.209 1.00 93.34  ? 330 ALA R N   1 
ATOM 2364 C CA  . ALA A 1 386 ? 104.710 109.933 123.282 1.00 93.34  ? 330 ALA R CA  1 
ATOM 2365 C C   . ALA A 1 386 ? 103.721 110.973 123.800 1.00 93.34  ? 330 ALA R C   1 
ATOM 2366 O O   . ALA A 1 386 ? 102.538 110.941 123.463 1.00 93.34  ? 330 ALA R O   1 
ATOM 2367 C CB  . ALA A 1 386 ? 105.592 109.432 124.413 1.00 93.34  ? 330 ALA R CB  1 
ATOM 2368 N N   . ALA B 2 1   ? 104.204 133.979 76.228  1.00 100.85 ? 1   ALA D N   1 
ATOM 2369 C CA  . ALA B 2 1   ? 103.828 132.582 76.406  1.00 100.85 ? 1   ALA D CA  1 
ATOM 2370 C C   . ALA B 2 1   ? 104.994 131.724 76.913  1.00 100.85 ? 1   ALA D C   1 
ATOM 2371 O O   . ALA B 2 1   ? 104.791 130.858 77.764  1.00 100.85 ? 1   ALA D O   1 
ATOM 2372 C CB  . ALA B 2 1   ? 103.278 132.013 75.100  1.00 100.85 ? 1   ALA D CB  1 
ATOM 2373 N N   . PRO B 2 2   ? 106.203 131.943 76.402  1.00 96.55  ? 2   PRO D N   1 
ATOM 2374 C CA  . PRO B 2 2   ? 107.365 131.206 76.906  1.00 96.55  ? 2   PRO D CA  1 
ATOM 2375 C C   . PRO B 2 2   ? 107.821 131.764 78.250  1.00 96.55  ? 2   PRO D C   1 
ATOM 2376 O O   . PRO B 2 2   ? 107.269 132.727 78.775  1.00 96.55  ? 2   PRO D O   1 
ATOM 2377 C CB  . PRO B 2 2   ? 108.426 131.419 75.818  1.00 96.55  ? 2   PRO D CB  1 
ATOM 2378 C CG  . PRO B 2 2   ? 107.708 132.037 74.661  1.00 96.55  ? 2   PRO D CG  1 
ATOM 2379 C CD  . PRO B 2 2   ? 106.578 132.789 75.259  1.00 96.55  ? 2   PRO D CD  1 
ATOM 2380 N N   . LEU B 2 3   ? 108.855 131.134 78.801  1.00 93.23  ? 3   LEU D N   1 
ATOM 2381 C CA  . LEU B 2 3   ? 109.425 131.524 80.081  1.00 93.23  ? 3   LEU D CA  1 
ATOM 2382 C C   . LEU B 2 3   ? 110.936 131.611 79.948  1.00 93.23  ? 3   LEU D C   1 
ATOM 2383 O O   . LEU B 2 3   ? 111.536 131.023 79.046  1.00 93.23  ? 3   LEU D O   1 
ATOM 2384 C CB  . LEU B 2 3   ? 109.073 130.528 81.192  1.00 93.23  ? 3   LEU D CB  1 
ATOM 2385 C CG  . LEU B 2 3   ? 107.596 130.196 81.386  1.00 93.23  ? 3   LEU D CG  1 
ATOM 2386 C CD1 . LEU B 2 3   ? 107.459 128.897 82.154  1.00 93.23  ? 3   LEU D CD1 1 
ATOM 2387 C CD2 . LEU B 2 3   ? 106.885 131.323 82.105  1.00 93.23  ? 3   LEU D CD2 1 
ATOM 2388 N N   . ALA B 2 4   ? 111.548 132.356 80.863  1.00 89.21  ? 4   ALA D N   1 
ATOM 2389 C CA  . ALA B 2 4   ? 112.998 132.466 80.891  1.00 89.21  ? 4   ALA D CA  1 
ATOM 2390 C C   . ALA B 2 4   ? 113.410 133.172 82.172  1.00 89.21  ? 4   ALA D C   1 
ATOM 2391 O O   . ALA B 2 4   ? 112.762 134.124 82.614  1.00 89.21  ? 4   ALA D O   1 
ATOM 2392 C CB  . ALA B 2 4   ? 113.530 133.220 79.669  1.00 89.21  ? 4   ALA D CB  1 
ATOM 2393 N N   . THR B 2 5   ? 114.501 132.686 82.762  1.00 87.28  ? 5   THR D N   1 
ATOM 2394 C CA  . THR B 2 5   ? 115.130 133.336 83.903  1.00 87.28  ? 5   THR D CA  1 
ATOM 2395 C C   . THR B 2 5   ? 116.407 134.061 83.502  1.00 87.28  ? 5   THR D C   1 
ATOM 2396 O O   . THR B 2 5   ? 117.175 134.477 84.378  1.00 87.28  ? 5   THR D O   1 
ATOM 2397 C CB  . THR B 2 5   ? 115.429 132.318 85.008  1.00 87.28  ? 5   THR D CB  1 
ATOM 2398 O OG1 . THR B 2 5   ? 115.995 132.989 86.140  1.00 87.28  ? 5   THR D OG1 1 
ATOM 2399 C CG2 . THR B 2 5   ? 116.398 131.249 84.519  1.00 87.28  ? 5   THR D CG2 1 
ATOM 2400 N N   . GLU B 2 6   ? 116.657 134.210 82.201  1.00 76.26  ? 6   GLU D N   1 
ATOM 2401 C CA  . GLU B 2 6   ? 117.843 134.905 81.706  1.00 76.26  ? 6   GLU D CA  1 
ATOM 2402 C C   . GLU B 2 6   ? 117.433 135.628 80.427  1.00 76.26  ? 6   GLU D C   1 
ATOM 2403 O O   . GLU B 2 6   ? 117.362 135.009 79.363  1.00 76.26  ? 6   GLU D O   1 
ATOM 2404 C CB  . GLU B 2 6   ? 118.985 133.933 81.449  1.00 76.26  ? 6   GLU D CB  1 
ATOM 2405 C CG  . GLU B 2 6   ? 119.549 133.279 82.694  1.00 76.26  ? 6   GLU D CG  1 
ATOM 2406 C CD  . GLU B 2 6   ? 120.333 134.244 83.556  1.00 76.26  ? 6   GLU D CD  1 
ATOM 2407 O OE1 . GLU B 2 6   ? 120.579 135.382 83.106  1.00 76.26  ? 6   GLU D OE1 1 
ATOM 2408 O OE2 . GLU B 2 6   ? 120.704 133.867 84.686  1.00 76.26  ? 6   GLU D OE2 1 
ATOM 2409 N N   . LEU B 2 7   ? 117.159 136.924 80.538  1.00 69.49  ? 7   LEU D N   1 
ATOM 2410 C CA  . LEU B 2 7   ? 116.815 137.723 79.371  1.00 69.49  ? 7   LEU D CA  1 
ATOM 2411 C C   . LEU B 2 7   ? 118.061 137.957 78.530  1.00 69.49  ? 7   LEU D C   1 
ATOM 2412 O O   . LEU B 2 7   ? 119.112 138.333 79.056  1.00 69.49  ? 7   LEU D O   1 
ATOM 2413 C CB  . LEU B 2 7   ? 116.197 139.054 79.792  1.00 69.49  ? 7   LEU D CB  1 
ATOM 2414 C CG  . LEU B 2 7   ? 115.110 138.970 80.861  1.00 69.49  ? 7   LEU D CG  1 
ATOM 2415 C CD1 . LEU B 2 7   ? 114.477 140.327 81.075  1.00 69.49  ? 7   LEU D CD1 1 
ATOM 2416 C CD2 . LEU B 2 7   ? 114.059 137.948 80.482  1.00 69.49  ? 7   LEU D CD2 1 
ATOM 2417 N N   . ARG B 2 8   ? 117.944 137.731 77.226  1.00 78.34  ? 8   ARG D N   1 
ATOM 2418 C CA  . ARG B 2 8   ? 119.071 137.820 76.314  1.00 78.34  ? 8   ARG D CA  1 
ATOM 2419 C C   . ARG B 2 8   ? 118.685 138.649 75.100  1.00 78.34  ? 8   ARG D C   1 
ATOM 2420 O O   . ARG B 2 8   ? 117.505 138.847 74.803  1.00 78.34  ? 8   ARG D O   1 
ATOM 2421 C CB  . ARG B 2 8   ? 119.544 136.432 75.868  1.00 78.34  ? 8   ARG D CB  1 
ATOM 2422 C CG  . ARG B 2 8   ? 119.679 135.441 77.006  1.00 78.34  ? 8   ARG D CG  1 
ATOM 2423 C CD  . ARG B 2 8   ? 120.398 134.182 76.574  1.00 78.34  ? 8   ARG D CD  1 
ATOM 2424 N NE  . ARG B 2 8   ? 120.381 133.173 77.628  1.00 78.34  ? 8   ARG D NE  1 
ATOM 2425 C CZ  . ARG B 2 8   ? 121.448 132.728 78.278  1.00 78.34  ? 8   ARG D CZ  1 
ATOM 2426 N NH1 . ARG B 2 8   ? 122.664 133.179 78.014  1.00 78.34  ? 8   ARG D NH1 1 
ATOM 2427 N NH2 . ARG B 2 8   ? 121.292 131.808 79.225  1.00 78.34  ? 8   ARG D NH2 1 
ATOM 2428 N N   . CYS B 2 9   ? 119.705 139.130 74.397  1.00 91.16  ? 9   CYS D N   1 
ATOM 2429 C CA  . CYS B 2 9   ? 119.481 139.938 73.214  1.00 91.16  ? 9   CYS D CA  1 
ATOM 2430 C C   . CYS B 2 9   ? 118.730 139.126 72.161  1.00 91.16  ? 9   CYS D C   1 
ATOM 2431 O O   . CYS B 2 9   ? 118.802 137.898 72.111  1.00 91.16  ? 9   CYS D O   1 
ATOM 2432 C CB  . CYS B 2 9   ? 120.812 140.436 72.658  1.00 91.16  ? 9   CYS D CB  1 
ATOM 2433 S SG  . CYS B 2 9   ? 121.906 141.139 73.915  1.00 91.16  ? 9   CYS D SG  1 
ATOM 2434 N N   . GLN B 2 10  ? 117.995 139.837 71.309  1.00 85.36  ? 10  GLN D N   1 
ATOM 2435 C CA  . GLN B 2 10  ? 117.177 139.213 70.279  1.00 85.36  ? 10  GLN D CA  1 
ATOM 2436 C C   . GLN B 2 10  ? 117.890 139.124 68.938  1.00 85.36  ? 10  GLN D C   1 
ATOM 2437 O O   . GLN B 2 10  ? 117.267 138.740 67.946  1.00 85.36  ? 10  GLN D O   1 
ATOM 2438 C CB  . GLN B 2 10  ? 115.864 139.980 70.113  1.00 85.36  ? 10  GLN D CB  1 
ATOM 2439 C CG  . GLN B 2 10  ? 114.663 139.293 70.731  1.00 85.36  ? 10  GLN D CG  1 
ATOM 2440 C CD  . GLN B 2 10  ? 113.374 140.038 70.464  1.00 85.36  ? 10  GLN D CD  1 
ATOM 2441 O OE1 . GLN B 2 10  ? 112.977 140.220 69.315  1.00 85.36  ? 10  GLN D OE1 1 
ATOM 2442 N NE2 . GLN B 2 10  ? 112.716 140.481 71.527  1.00 85.36  ? 10  GLN D NE2 1 
ATOM 2443 N N   . CYS B 2 11  ? 119.172 139.476 68.876  1.00 89.90  ? 11  CYS D N   1 
ATOM 2444 C CA  . CYS B 2 11  ? 119.910 139.431 67.622  1.00 89.90  ? 11  CYS D CA  1 
ATOM 2445 C C   . CYS B 2 11  ? 121.353 139.046 67.900  1.00 89.90  ? 11  CYS D C   1 
ATOM 2446 O O   . CYS B 2 11  ? 121.993 139.632 68.777  1.00 89.90  ? 11  CYS D O   1 
ATOM 2447 C CB  . CYS B 2 11  ? 119.857 140.781 66.899  1.00 89.90  ? 11  CYS D CB  1 
ATOM 2448 S SG  . CYS B 2 11  ? 118.205 141.277 66.371  1.00 89.90  ? 11  CYS D SG  1 
ATOM 2449 N N   . LEU B 2 12  ? 121.858 138.070 67.148  1.00 93.79  ? 12  LEU D N   1 
ATOM 2450 C CA  . LEU B 2 12  ? 123.252 137.654 67.237  1.00 93.79  ? 12  LEU D CA  1 
ATOM 2451 C C   . LEU B 2 12  ? 124.140 138.383 66.241  1.00 93.79  ? 12  LEU D C   1 
ATOM 2452 O O   . LEU B 2 12  ? 125.268 138.751 66.578  1.00 93.79  ? 12  LEU D O   1 
ATOM 2453 C CB  . LEU B 2 12  ? 123.368 136.145 67.009  1.00 93.79  ? 12  LEU D CB  1 
ATOM 2454 C CG  . LEU B 2 12  ? 122.948 135.259 68.182  1.00 93.79  ? 12  LEU D CG  1 
ATOM 2455 C CD1 . LEU B 2 12  ? 122.983 133.801 67.772  1.00 93.79  ? 12  LEU D CD1 1 
ATOM 2456 C CD2 . LEU B 2 12  ? 123.836 135.494 69.391  1.00 93.79  ? 12  LEU D CD2 1 
ATOM 2457 N N   . GLN B 2 13  ? 123.655 138.596 65.022  1.00 98.93  ? 13  GLN D N   1 
ATOM 2458 C CA  . GLN B 2 13  ? 124.349 139.410 64.039  1.00 98.93  ? 13  GLN D CA  1 
ATOM 2459 C C   . GLN B 2 13  ? 123.308 140.121 63.190  1.00 98.93  ? 13  GLN D C   1 
ATOM 2460 O O   . GLN B 2 13  ? 122.156 139.693 63.100  1.00 98.93  ? 13  GLN D O   1 
ATOM 2461 C CB  . GLN B 2 13  ? 125.292 138.572 63.167  1.00 98.93  ? 13  GLN D CB  1 
ATOM 2462 C CG  . GLN B 2 13  ? 124.597 137.631 62.201  1.00 98.93  ? 13  GLN D CG  1 
ATOM 2463 C CD  . GLN B 2 13  ? 125.580 136.778 61.425  1.00 98.93  ? 13  GLN D CD  1 
ATOM 2464 O OE1 . GLN B 2 13  ? 126.733 136.623 61.826  1.00 98.93  ? 13  GLN D OE1 1 
ATOM 2465 N NE2 . GLN B 2 13  ? 125.129 136.219 60.308  1.00 98.93  ? 13  GLN D NE2 1 
ATOM 2466 N N   . THR B 2 14  ? 123.728 141.215 62.559  1.00 98.35  ? 14  THR D N   1 
ATOM 2467 C CA  . THR B 2 14  ? 122.805 142.119 61.894  1.00 98.35  ? 14  THR D CA  1 
ATOM 2468 C C   . THR B 2 14  ? 123.230 142.324 60.448  1.00 98.35  ? 14  THR D C   1 
ATOM 2469 O O   . THR B 2 14  ? 124.390 142.122 60.083  1.00 98.35  ? 14  THR D O   1 
ATOM 2470 C CB  . THR B 2 14  ? 122.739 143.473 62.609  1.00 98.35  ? 14  THR D CB  1 
ATOM 2471 O OG1 . THR B 2 14  ? 124.026 144.103 62.567  1.00 98.35  ? 14  THR D OG1 1 
ATOM 2472 C CG2 . THR B 2 14  ? 122.319 143.291 64.058  1.00 98.35  ? 14  THR D CG2 1 
ATOM 2473 N N   . LEU B 2 15  ? 122.266 142.732 59.629  1.00 99.83  ? 15  LEU D N   1 
ATOM 2474 C CA  . LEU B 2 15  ? 122.493 143.044 58.227  1.00 99.83  ? 15  LEU D CA  1 
ATOM 2475 C C   . LEU B 2 15  ? 122.020 144.464 57.950  1.00 99.83  ? 15  LEU D C   1 
ATOM 2476 O O   . LEU B 2 15  ? 121.417 145.122 58.801  1.00 99.83  ? 15  LEU D O   1 
ATOM 2477 C CB  . LEU B 2 15  ? 121.768 142.058 57.303  1.00 99.83  ? 15  LEU D CB  1 
ATOM 2478 C CG  . LEU B 2 15  ? 122.257 140.612 57.359  1.00 99.83  ? 15  LEU D CG  1 
ATOM 2479 C CD1 . LEU B 2 15  ? 121.358 139.722 56.520  1.00 99.83  ? 15  LEU D CD1 1 
ATOM 2480 C CD2 . LEU B 2 15  ? 123.701 140.512 56.892  1.00 99.83  ? 15  LEU D CD2 1 
ATOM 2481 N N   . GLN B 2 16  ? 122.309 144.935 56.741  1.00 106.38 ? 16  GLN D N   1 
ATOM 2482 C CA  . GLN B 2 16  ? 121.950 146.276 56.307  1.00 106.38 ? 16  GLN D CA  1 
ATOM 2483 C C   . GLN B 2 16  ? 121.542 146.239 54.841  1.00 106.38 ? 16  GLN D C   1 
ATOM 2484 O O   . GLN B 2 16  ? 122.286 145.724 54.000  1.00 106.38 ? 16  GLN D O   1 
ATOM 2485 C CB  . GLN B 2 16  ? 123.122 147.238 56.524  1.00 106.38 ? 16  GLN D CB  1 
ATOM 2486 C CG  . GLN B 2 16  ? 124.350 146.917 55.686  1.00 106.38 ? 16  GLN D CG  1 
ATOM 2487 C CD  . GLN B 2 16  ? 125.547 147.772 56.054  1.00 106.38 ? 16  GLN D CD  1 
ATOM 2488 O OE1 . GLN B 2 16  ? 125.643 148.276 57.173  1.00 106.38 ? 16  GLN D OE1 1 
ATOM 2489 N NE2 . GLN B 2 16  ? 126.469 147.938 55.113  1.00 106.38 ? 16  GLN D NE2 1 
ATOM 2490 N N   . GLY B 2 17  ? 120.361 146.778 54.540  1.00 109.73 ? 17  GLY D N   1 
ATOM 2491 C CA  . GLY B 2 17  ? 119.908 146.879 53.165  1.00 109.73 ? 17  GLY D CA  1 
ATOM 2492 C C   . GLY B 2 17  ? 118.570 146.225 52.881  1.00 109.73 ? 17  GLY D C   1 
ATOM 2493 O O   . GLY B 2 17  ? 118.194 146.072 51.715  1.00 109.73 ? 17  GLY D O   1 
ATOM 2494 N N   . ILE B 2 18  ? 117.839 145.831 53.927  1.00 106.34 ? 18  ILE D N   1 
ATOM 2495 C CA  . ILE B 2 18  ? 116.523 145.239 53.724  1.00 106.34 ? 18  ILE D CA  1 
ATOM 2496 C C   . ILE B 2 18  ? 115.652 146.214 52.951  1.00 106.34 ? 18  ILE D C   1 
ATOM 2497 O O   . ILE B 2 18  ? 115.495 147.375 53.343  1.00 106.34 ? 18  ILE D O   1 
ATOM 2498 C CB  . ILE B 2 18  ? 115.891 144.862 55.077  1.00 106.34 ? 18  ILE D CB  1 
ATOM 2499 C CG1 . ILE B 2 18  ? 116.501 143.565 55.617  1.00 106.34 ? 18  ILE D CG1 1 
ATOM 2500 C CG2 . ILE B 2 18  ? 114.387 144.716 54.943  1.00 106.34 ? 18  ILE D CG2 1 
ATOM 2501 C CD1 . ILE B 2 18  ? 116.094 142.312 54.858  1.00 106.34 ? 18  ILE D CD1 1 
ATOM 2502 N N   . HIS B 2 19  ? 115.080 145.744 51.845  1.00 120.88 ? 19  HIS D N   1 
ATOM 2503 C CA  . HIS B 2 19  ? 114.308 146.616 50.970  1.00 120.88 ? 19  HIS D CA  1 
ATOM 2504 C C   . HIS B 2 19  ? 112.949 146.926 51.585  1.00 120.88 ? 19  HIS D C   1 
ATOM 2505 O O   . HIS B 2 19  ? 112.242 146.024 52.044  1.00 120.88 ? 19  HIS D O   1 
ATOM 2506 C CB  . HIS B 2 19  ? 114.132 145.961 49.602  1.00 120.88 ? 19  HIS D CB  1 
ATOM 2507 C CG  . HIS B 2 19  ? 115.416 145.773 48.857  1.00 120.88 ? 19  HIS D CG  1 
ATOM 2508 N ND1 . HIS B 2 19  ? 116.252 144.700 49.076  1.00 120.88 ? 19  HIS D ND1 1 
ATOM 2509 C CD2 . HIS B 2 19  ? 116.009 146.523 47.898  1.00 120.88 ? 19  HIS D CD2 1 
ATOM 2510 C CE1 . HIS B 2 19  ? 117.304 144.796 48.283  1.00 120.88 ? 19  HIS D CE1 1 
ATOM 2511 N NE2 . HIS B 2 19  ? 117.181 145.893 47.558  1.00 120.88 ? 19  HIS D NE2 1 
ATOM 2512 N N   . LEU B 2 20  ? 112.576 148.210 51.576  1.00 119.55 ? 20  LEU D N   1 
ATOM 2513 C CA  . LEU B 2 20  ? 111.314 148.626 52.181  1.00 119.55 ? 20  LEU D CA  1 
ATOM 2514 C C   . LEU B 2 20  ? 110.125 147.901 51.568  1.00 119.55 ? 20  LEU D C   1 
ATOM 2515 O O   . LEU B 2 20  ? 109.139 147.632 52.263  1.00 119.55 ? 20  LEU D O   1 
ATOM 2516 C CB  . LEU B 2 20  ? 111.138 150.139 52.034  1.00 119.55 ? 20  LEU D CB  1 
ATOM 2517 C CG  . LEU B 2 20  ? 109.839 150.731 52.591  1.00 119.55 ? 20  LEU D CG  1 
ATOM 2518 C CD1 . LEU B 2 20  ? 109.734 150.511 54.091  1.00 119.55 ? 20  LEU D CD1 1 
ATOM 2519 C CD2 . LEU B 2 20  ? 109.745 152.211 52.262  1.00 119.55 ? 20  LEU D CD2 1 
ATOM 2520 N N   . LYS B 2 21  ? 110.194 147.576 50.275  1.00 123.61 ? 21  LYS D N   1 
ATOM 2521 C CA  . LYS B 2 21  ? 109.072 146.914 49.621  1.00 123.61 ? 21  LYS D CA  1 
ATOM 2522 C C   . LYS B 2 21  ? 108.710 145.609 50.314  1.00 123.61 ? 21  LYS D C   1 
ATOM 2523 O O   . LYS B 2 21  ? 107.554 145.174 50.257  1.00 123.61 ? 21  LYS D O   1 
ATOM 2524 C CB  . LYS B 2 21  ? 109.389 146.664 48.154  1.00 30.00  ? 21  LYS D CB  1 
ATOM 2525 N N   . ASN B 2 22  ? 109.677 144.973 50.972  1.00 117.66 ? 22  ASN D N   1 
ATOM 2526 C CA  . ASN B 2 22  ? 109.462 143.706 51.654  1.00 117.66 ? 22  ASN D CA  1 
ATOM 2527 C C   . ASN B 2 22  ? 109.289 143.865 53.159  1.00 117.66 ? 22  ASN D C   1 
ATOM 2528 O O   . ASN B 2 22  ? 109.233 142.859 53.871  1.00 117.66 ? 22  ASN D O   1 
ATOM 2529 C CB  . ASN B 2 22  ? 110.625 142.754 51.366  1.00 117.66 ? 22  ASN D CB  1 
ATOM 2530 C CG  . ASN B 2 22  ? 111.029 142.753 49.905  1.00 117.66 ? 22  ASN D CG  1 
ATOM 2531 O OD1 . ASN B 2 22  ? 112.181 143.027 49.568  1.00 117.66 ? 22  ASN D OD1 1 
ATOM 2532 N ND2 . ASN B 2 22  ? 110.081 142.444 49.028  1.00 117.66 ? 22  ASN D ND2 1 
ATOM 2533 N N   . ILE B 2 23  ? 109.196 145.094 53.660  1.00 109.09 ? 23  ILE D N   1 
ATOM 2534 C CA  . ILE B 2 23  ? 109.073 145.352 55.091  1.00 109.09 ? 23  ILE D CA  1 
ATOM 2535 C C   . ILE B 2 23  ? 107.599 145.524 55.423  1.00 109.09 ? 23  ILE D C   1 
ATOM 2536 O O   . ILE B 2 23  ? 106.899 146.322 54.788  1.00 109.09 ? 23  ILE D O   1 
ATOM 2537 C CB  . ILE B 2 23  ? 109.873 146.594 55.516  1.00 109.09 ? 23  ILE D CB  1 
ATOM 2538 C CG1 . ILE B 2 23  ? 111.343 146.435 55.143  1.00 109.09 ? 23  ILE D CG1 1 
ATOM 2539 C CG2 . ILE B 2 23  ? 109.743 146.819 57.017  1.00 109.09 ? 23  ILE D CG2 1 
ATOM 2540 C CD1 . ILE B 2 23  ? 112.200 147.604 55.560  1.00 109.09 ? 23  ILE D CD1 1 
ATOM 2541 N N   . GLN B 2 24  ? 107.128 144.775 56.418  1.00 107.77 ? 24  GLN D N   1 
ATOM 2542 C CA  . GLN B 2 24  ? 105.784 144.966 56.947  1.00 107.77 ? 24  GLN D CA  1 
ATOM 2543 C C   . GLN B 2 24  ? 105.795 145.815 58.211  1.00 107.77 ? 24  GLN D C   1 
ATOM 2544 O O   . GLN B 2 24  ? 104.923 146.671 58.388  1.00 107.77 ? 24  GLN D O   1 
ATOM 2545 C CB  . GLN B 2 24  ? 105.131 143.611 57.234  1.00 107.77 ? 24  GLN D CB  1 
ATOM 2546 C CG  . GLN B 2 24  ? 103.706 143.702 57.763  1.00 107.77 ? 24  GLN D CG  1 
ATOM 2547 C CD  . GLN B 2 24  ? 103.149 142.352 58.170  1.00 107.77 ? 24  GLN D CD  1 
ATOM 2548 O OE1 . GLN B 2 24  ? 103.847 141.536 58.771  1.00 107.77 ? 24  GLN D OE1 1 
ATOM 2549 N NE2 . GLN B 2 24  ? 101.886 142.110 57.841  1.00 107.77 ? 24  GLN D NE2 1 
ATOM 2550 N N   . SER B 2 25  ? 106.768 145.596 59.093  1.00 99.03  ? 25  SER D N   1 
ATOM 2551 C CA  . SER B 2 25  ? 106.868 146.379 60.316  1.00 99.03  ? 25  SER D CA  1 
ATOM 2552 C C   . SER B 2 25  ? 108.318 146.414 60.773  1.00 99.03  ? 25  SER D C   1 
ATOM 2553 O O   . SER B 2 25  ? 109.130 145.577 60.378  1.00 99.03  ? 25  SER D O   1 
ATOM 2554 C CB  . SER B 2 25  ? 105.979 145.807 61.423  1.00 99.03  ? 25  SER D CB  1 
ATOM 2555 O OG  . SER B 2 25  ? 106.531 144.612 61.946  1.00 99.03  ? 25  SER D OG  1 
ATOM 2556 N N   . VAL B 2 26  ? 108.634 147.394 61.616  1.00 87.78  ? 26  VAL D N   1 
ATOM 2557 C CA  . VAL B 2 26  ? 109.959 147.533 62.208  1.00 87.78  ? 26  VAL D CA  1 
ATOM 2558 C C   . VAL B 2 26  ? 109.793 147.794 63.697  1.00 87.78  ? 26  VAL D C   1 
ATOM 2559 O O   . VAL B 2 26  ? 108.966 148.619 64.098  1.00 87.78  ? 26  VAL D O   1 
ATOM 2560 C CB  . VAL B 2 26  ? 110.766 148.667 61.551  1.00 87.78  ? 26  VAL D CB  1 
ATOM 2561 C CG1 . VAL B 2 26  ? 112.094 148.845 62.261  1.00 87.78  ? 26  VAL D CG1 1 
ATOM 2562 C CG2 . VAL B 2 26  ? 110.982 148.379 60.080  1.00 87.78  ? 26  VAL D CG2 1 
ATOM 2563 N N   . LYS B 2 27  ? 110.573 147.091 64.510  1.00 76.46  ? 27  LYS D N   1 
ATOM 2564 C CA  . LYS B 2 27  ? 110.569 147.247 65.956  1.00 76.46  ? 27  LYS D CA  1 
ATOM 2565 C C   . LYS B 2 27  ? 111.942 147.720 66.402  1.00 76.46  ? 27  LYS D C   1 
ATOM 2566 O O   . LYS B 2 27  ? 112.959 147.144 66.002  1.00 76.46  ? 27  LYS D O   1 
ATOM 2567 C CB  . LYS B 2 27  ? 110.216 145.928 66.643  1.00 76.46  ? 27  LYS D CB  1 
ATOM 2568 C CG  . LYS B 2 27  ? 110.175 145.998 68.159  1.00 76.46  ? 27  LYS D CG  1 
ATOM 2569 C CD  . LYS B 2 27  ? 110.306 144.621 68.777  1.00 76.46  ? 27  LYS D CD  1 
ATOM 2570 C CE  . LYS B 2 27  ? 110.513 144.704 70.275  1.00 76.46  ? 27  LYS D CE  1 
ATOM 2571 N NZ  . LYS B 2 27  ? 110.531 143.360 70.911  1.00 76.46  ? 27  LYS D NZ  1 
ATOM 2572 N N   . VAL B 2 28  ? 111.970 148.764 67.226  1.00 78.08  ? 28  VAL D N   1 
ATOM 2573 C CA  . VAL B 2 28  ? 113.204 149.310 67.778  1.00 78.08  ? 28  VAL D CA  1 
ATOM 2574 C C   . VAL B 2 28  ? 113.118 149.210 69.293  1.00 78.08  ? 28  VAL D C   1 
ATOM 2575 O O   . VAL B 2 28  ? 112.145 149.674 69.899  1.00 78.08  ? 28  VAL D O   1 
ATOM 2576 C CB  . VAL B 2 28  ? 113.438 150.760 67.331  1.00 78.08  ? 28  VAL D CB  1 
ATOM 2577 C CG1 . VAL B 2 28  ? 114.777 151.256 67.836  1.00 78.08  ? 28  VAL D CG1 1 
ATOM 2578 C CG2 . VAL B 2 28  ? 113.368 150.868 65.820  1.00 78.08  ? 28  VAL D CG2 1 
ATOM 2579 N N   . LYS B 2 29  ? 114.130 148.602 69.902  1.00 75.96  ? 29  LYS D N   1 
ATOM 2580 C CA  . LYS B 2 29  ? 114.182 148.390 71.340  1.00 75.96  ? 29  LYS D CA  1 
ATOM 2581 C C   . LYS B 2 29  ? 115.454 149.018 71.888  1.00 75.96  ? 29  LYS D C   1 
ATOM 2582 O O   . LYS B 2 29  ? 116.557 148.674 71.451  1.00 75.96  ? 29  LYS D O   1 
ATOM 2583 C CB  . LYS B 2 29  ? 114.139 146.898 71.670  1.00 75.96  ? 29  LYS D CB  1 
ATOM 2584 C CG  . LYS B 2 29  ? 113.920 146.591 73.135  1.00 75.96  ? 29  LYS D CG  1 
ATOM 2585 C CD  . LYS B 2 29  ? 113.629 145.118 73.348  1.00 75.96  ? 29  LYS D CD  1 
ATOM 2586 C CE  . LYS B 2 29  ? 113.088 144.858 74.740  1.00 75.96  ? 29  LYS D CE  1 
ATOM 2587 N NZ  . LYS B 2 29  ? 112.653 143.446 74.912  1.00 75.96  ? 29  LYS D NZ  1 
ATOM 2588 N N   . SER B 2 30  ? 115.295 149.932 72.839  1.00 73.18  ? 30  SER D N   1 
ATOM 2589 C CA  . SER B 2 30  ? 116.417 150.654 73.413  1.00 73.18  ? 30  SER D CA  1 
ATOM 2590 C C   . SER B 2 30  ? 117.123 149.809 74.466  1.00 73.18  ? 30  SER D C   1 
ATOM 2591 O O   . SER B 2 30  ? 116.566 148.830 74.965  1.00 73.18  ? 30  SER D O   1 
ATOM 2592 C CB  . SER B 2 30  ? 115.934 151.959 74.034  1.00 73.18  ? 30  SER D CB  1 
ATOM 2593 O OG  . SER B 2 30  ? 114.928 151.718 75.000  1.00 73.18  ? 30  SER D OG  1 
ATOM 2594 N N   . PRO B 2 31  ? 118.354 150.170 74.826  1.00 69.49  ? 31  PRO D N   1 
ATOM 2595 C CA  . PRO B 2 31  ? 119.089 149.376 75.813  1.00 69.49  ? 31  PRO D CA  1 
ATOM 2596 C C   . PRO B 2 31  ? 118.340 149.303 77.131  1.00 69.49  ? 31  PRO D C   1 
ATOM 2597 O O   . PRO B 2 31  ? 117.646 150.239 77.530  1.00 69.49  ? 31  PRO D O   1 
ATOM 2598 C CB  . PRO B 2 31  ? 120.414 150.130 75.960  1.00 69.49  ? 31  PRO D CB  1 
ATOM 2599 C CG  . PRO B 2 31  ? 120.547 150.900 74.700  1.00 69.49  ? 31  PRO D CG  1 
ATOM 2600 C CD  . PRO B 2 31  ? 119.156 151.304 74.341  1.00 69.49  ? 31  PRO D CD  1 
ATOM 2601 N N   . GLY B 2 32  ? 118.481 148.169 77.806  1.00 69.49  ? 32  GLY D N   1 
ATOM 2602 C CA  . GLY B 2 32  ? 117.767 147.928 79.034  1.00 69.49  ? 32  GLY D CA  1 
ATOM 2603 C C   . GLY B 2 32  ? 118.190 146.629 79.684  1.00 69.49  ? 32  GLY D C   1 
ATOM 2604 O O   . GLY B 2 32  ? 119.263 146.091 79.400  1.00 69.49  ? 32  GLY D O   1 
ATOM 2605 N N   . PRO B 2 33  ? 117.351 146.094 80.572  1.00 69.49  ? 33  PRO D N   1 
ATOM 2606 C CA  . PRO B 2 33  ? 117.708 144.843 81.254  1.00 69.49  ? 33  PRO D CA  1 
ATOM 2607 C C   . PRO B 2 33  ? 117.846 143.657 80.315  1.00 69.49  ? 33  PRO D C   1 
ATOM 2608 O O   . PRO B 2 33  ? 118.316 142.594 80.730  1.00 69.49  ? 33  PRO D O   1 
ATOM 2609 C CB  . PRO B 2 33  ? 116.554 144.644 82.246  1.00 69.49  ? 33  PRO D CB  1 
ATOM 2610 C CG  . PRO B 2 33  ? 115.443 145.472 81.723  1.00 69.49  ? 33  PRO D CG  1 
ATOM 2611 C CD  . PRO B 2 33  ? 116.089 146.650 81.082  1.00 69.49  ? 33  PRO D CD  1 
ATOM 2612 N N   . HIS B 2 34  ? 117.447 143.813 79.053  1.00 70.38  ? 34  HIS D N   1 
ATOM 2613 C CA  . HIS B 2 34  ? 117.557 142.722 78.094  1.00 70.38  ? 34  HIS D CA  1 
ATOM 2614 C C   . HIS B 2 34  ? 118.931 142.701 77.438  1.00 70.38  ? 34  HIS D C   1 
ATOM 2615 O O   . HIS B 2 34  ? 119.670 141.721 77.566  1.00 70.38  ? 34  HIS D O   1 
ATOM 2616 C CB  . HIS B 2 34  ? 116.475 142.840 77.020  1.00 70.38  ? 34  HIS D CB  1 
ATOM 2617 C CG  . HIS B 2 34  ? 115.094 143.008 77.569  1.00 70.38  ? 34  HIS D CG  1 
ATOM 2618 N ND1 . HIS B 2 34  ? 114.677 144.161 78.196  1.00 70.38  ? 34  HIS D ND1 1 
ATOM 2619 C CD2 . HIS B 2 34  ? 114.035 142.165 77.588  1.00 70.38  ? 34  HIS D CD2 1 
ATOM 2620 C CE1 . HIS B 2 34  ? 113.419 144.023 78.576  1.00 70.38  ? 34  HIS D CE1 1 
ATOM 2621 N NE2 . HIS B 2 34  ? 113.006 142.821 78.219  1.00 70.38  ? 34  HIS D NE2 1 
ATOM 2622 N N   . CYS B 2 35  ? 119.285 143.776 76.743  1.00 76.76  ? 35  CYS D N   1 
ATOM 2623 C CA  . CYS B 2 35  ? 120.540 143.867 76.016  1.00 76.76  ? 35  CYS D CA  1 
ATOM 2624 C C   . CYS B 2 35  ? 121.180 145.223 76.262  1.00 76.76  ? 35  CYS D C   1 
ATOM 2625 O O   . CYS B 2 35  ? 120.501 146.195 76.600  1.00 76.76  ? 35  CYS D O   1 
ATOM 2626 C CB  . CYS B 2 35  ? 120.329 143.664 74.514  1.00 76.76  ? 35  CYS D CB  1 
ATOM 2627 S SG  . CYS B 2 35  ? 121.809 143.146 73.618  1.00 76.76  ? 35  CYS D SG  1 
ATOM 2628 N N   . ALA B 2 36  ? 122.498 145.278 76.094  1.00 70.32  ? 36  ALA D N   1 
ATOM 2629 C CA  . ALA B 2 36  ? 123.243 146.516 76.263  1.00 70.32  ? 36  ALA D CA  1 
ATOM 2630 C C   . ALA B 2 36  ? 123.292 147.358 74.997  1.00 70.32  ? 36  ALA D C   1 
ATOM 2631 O O   . ALA B 2 36  ? 123.897 148.434 75.013  1.00 70.32  ? 36  ALA D O   1 
ATOM 2632 C CB  . ALA B 2 36  ? 124.672 146.213 76.720  1.00 70.32  ? 36  ALA D CB  1 
ATOM 2633 N N   . GLN B 2 37  ? 122.685 146.898 73.909  1.00 77.87  ? 37  GLN D N   1 
ATOM 2634 C CA  . GLN B 2 37  ? 122.690 147.607 72.640  1.00 77.87  ? 37  GLN D CA  1 
ATOM 2635 C C   . GLN B 2 37  ? 121.273 147.700 72.089  1.00 77.87  ? 37  GLN D C   1 
ATOM 2636 O O   . GLN B 2 37  ? 120.430 146.835 72.333  1.00 77.87  ? 37  GLN D O   1 
ATOM 2637 C CB  . GLN B 2 37  ? 123.594 146.902 71.622  1.00 77.87  ? 37  GLN D CB  1 
ATOM 2638 C CG  . GLN B 2 37  ? 125.001 146.598 72.118  1.00 77.87  ? 37  GLN D CG  1 
ATOM 2639 C CD  . GLN B 2 37  ? 126.029 147.568 71.578  1.00 77.87  ? 37  GLN D CD  1 
ATOM 2640 O OE1 . GLN B 2 37  ? 126.312 148.596 72.192  1.00 77.87  ? 37  GLN D OE1 1 
ATOM 2641 N NE2 . GLN B 2 37  ? 126.595 147.247 70.421  1.00 77.87  ? 37  GLN D NE2 1 
ATOM 2642 N N   . THR B 2 38  ? 121.017 148.767 71.339  1.00 80.12  ? 38  THR D N   1 
ATOM 2643 C CA  . THR B 2 38  ? 119.730 148.916 70.679  1.00 80.12  ? 38  THR D CA  1 
ATOM 2644 C C   . THR B 2 38  ? 119.542 147.821 69.637  1.00 80.12  ? 38  THR D C   1 
ATOM 2645 O O   . THR B 2 38  ? 120.488 147.406 68.963  1.00 80.12  ? 38  THR D O   1 
ATOM 2646 C CB  . THR B 2 38  ? 119.620 150.288 70.017  1.00 80.12  ? 38  THR D CB  1 
ATOM 2647 O OG1 . THR B 2 38  ? 119.552 151.303 71.023  1.00 80.12  ? 38  THR D OG1 1 
ATOM 2648 C CG2 . THR B 2 38  ? 118.385 150.370 69.144  1.00 80.12  ? 38  THR D CG2 1 
ATOM 2649 N N   . GLU B 2 39  ? 118.305 147.350 69.511  1.00 80.39  ? 39  GLU D N   1 
ATOM 2650 C CA  . GLU B 2 39  ? 117.964 146.279 68.585  1.00 80.39  ? 39  GLU D CA  1 
ATOM 2651 C C   . GLU B 2 39  ? 116.918 146.771 67.601  1.00 80.39  ? 39  GLU D C   1 
ATOM 2652 O O   . GLU B 2 39  ? 115.941 147.411 67.997  1.00 80.39  ? 39  GLU D O   1 
ATOM 2653 C CB  . GLU B 2 39  ? 117.442 145.052 69.332  1.00 80.39  ? 39  GLU D CB  1 
ATOM 2654 C CG  . GLU B 2 39  ? 118.364 144.561 70.426  1.00 80.39  ? 39  GLU D CG  1 
ATOM 2655 C CD  . GLU B 2 39  ? 117.800 143.370 71.166  1.00 80.39  ? 39  GLU D CD  1 
ATOM 2656 O OE1 . GLU B 2 39  ? 116.679 143.479 71.704  1.00 80.39  ? 39  GLU D OE1 1 
ATOM 2657 O OE2 . GLU B 2 39  ? 118.479 142.325 71.212  1.00 80.39  ? 39  GLU D OE2 1 
ATOM 2658 N N   . VAL B 2 40  ? 117.125 146.475 66.323  1.00 84.95  ? 40  VAL D N   1 
ATOM 2659 C CA  . VAL B 2 40  ? 116.164 146.776 65.269  1.00 84.95  ? 40  VAL D CA  1 
ATOM 2660 C C   . VAL B 2 40  ? 115.801 145.462 64.595  1.00 84.95  ? 40  VAL D C   1 
ATOM 2661 O O   . VAL B 2 40  ? 116.682 144.742 64.113  1.00 84.95  ? 40  VAL D O   1 
ATOM 2662 C CB  . VAL B 2 40  ? 116.730 147.779 64.255  1.00 84.95  ? 40  VAL D CB  1 
ATOM 2663 C CG1 . VAL B 2 40  ? 115.657 148.187 63.262  1.00 84.95  ? 40  VAL D CG1 1 
ATOM 2664 C CG2 . VAL B 2 40  ? 117.291 148.993 64.968  1.00 84.95  ? 40  VAL D CG2 1 
ATOM 2665 N N   . ILE B 2 41  ? 114.510 145.148 64.558  1.00 79.04  ? 41  ILE D N   1 
ATOM 2666 C CA  . ILE B 2 41  ? 114.019 143.891 64.002  1.00 79.04  ? 41  ILE D CA  1 
ATOM 2667 C C   . ILE B 2 41  ? 112.919 144.224 63.006  1.00 79.04  ? 41  ILE D C   1 
ATOM 2668 O O   . ILE B 2 41  ? 111.899 144.811 63.380  1.00 79.04  ? 41  ILE D O   1 
ATOM 2669 C CB  . ILE B 2 41  ? 113.498 142.946 65.090  1.00 79.04  ? 41  ILE D CB  1 
ATOM 2670 C CG1 . ILE B 2 41  ? 114.598 142.665 66.112  1.00 79.04  ? 41  ILE D CG1 1 
ATOM 2671 C CG2 . ILE B 2 41  ? 113.000 141.656 64.472  1.00 79.04  ? 41  ILE D CG2 1 
ATOM 2672 C CD1 . ILE B 2 41  ? 114.126 141.895 67.314  1.00 79.04  ? 41  ILE D CD1 1 
ATOM 2673 N N   . ALA B 2 42  ? 113.113 143.846 61.748  1.00 88.88  ? 42  ALA D N   1 
ATOM 2674 C CA  . ALA B 2 42  ? 112.123 144.092 60.713  1.00 88.88  ? 42  ALA D CA  1 
ATOM 2675 C C   . ALA B 2 42  ? 111.367 142.808 60.410  1.00 88.88  ? 42  ALA D C   1 
ATOM 2676 O O   . ALA B 2 42  ? 111.972 141.789 60.059  1.00 88.88  ? 42  ALA D O   1 
ATOM 2677 C CB  . ALA B 2 42  ? 112.787 144.624 59.444  1.00 88.88  ? 42  ALA D CB  1 
ATOM 2678 N N   . THR B 2 43  ? 110.048 142.859 60.555  1.00 94.49  ? 43  THR D N   1 
ATOM 2679 C CA  . THR B 2 43  ? 109.168 141.763 60.180  1.00 94.49  ? 43  THR D CA  1 
ATOM 2680 C C   . THR B 2 43  ? 108.694 142.007 58.755  1.00 94.49  ? 43  THR D C   1 
ATOM 2681 O O   . THR B 2 43  ? 108.035 143.017 58.480  1.00 94.49  ? 43  THR D O   1 
ATOM 2682 C CB  . THR B 2 43  ? 107.979 141.661 61.134  1.00 94.49  ? 43  THR D CB  1 
ATOM 2683 O OG1 . THR B 2 43  ? 108.449 141.412 62.464  1.00 94.49  ? 43  THR D OG1 1 
ATOM 2684 C CG2 . THR B 2 43  ? 107.050 140.537 60.712  1.00 94.49  ? 43  THR D CG2 1 
ATOM 2685 N N   . LEU B 2 44  ? 109.038 141.088 57.857  1.00 103.63 ? 44  LEU D N   1 
ATOM 2686 C CA  . LEU B 2 44  ? 108.721 141.227 56.446  1.00 103.63 ? 44  LEU D CA  1 
ATOM 2687 C C   . LEU B 2 44  ? 107.297 140.755 56.164  1.00 103.63 ? 44  LEU D C   1 
ATOM 2688 O O   . LEU B 2 44  ? 106.621 140.170 57.015  1.00 103.63 ? 44  LEU D O   1 
ATOM 2689 C CB  . LEU B 2 44  ? 109.720 140.439 55.601  1.00 103.63 ? 44  LEU D CB  1 
ATOM 2690 C CG  . LEU B 2 44  ? 111.194 140.665 55.942  1.00 103.63 ? 44  LEU D CG  1 
ATOM 2691 C CD1 . LEU B 2 44  ? 112.082 139.836 55.032  1.00 103.63 ? 44  LEU D CD1 1 
ATOM 2692 C CD2 . LEU B 2 44  ? 111.555 142.135 55.845  1.00 103.63 ? 44  LEU D CD2 1 
ATOM 2693 N N   . LYS B 2 45  ? 106.840 141.016 54.938  1.00 109.24 ? 45  LYS D N   1 
ATOM 2694 C CA  . LYS B 2 45  ? 105.487 140.650 54.541  1.00 109.24 ? 45  LYS D CA  1 
ATOM 2695 C C   . LYS B 2 45  ? 105.284 139.145 54.447  1.00 109.24 ? 45  LYS D C   1 
ATOM 2696 O O   . LYS B 2 45  ? 104.135 138.693 54.488  1.00 109.24 ? 45  LYS D O   1 
ATOM 2697 C CB  . LYS B 2 45  ? 105.144 141.297 53.198  1.00 109.24 ? 45  LYS D CB  1 
ATOM 2698 C CG  . LYS B 2 45  ? 104.908 142.794 53.280  1.00 109.24 ? 45  LYS D CG  1 
ATOM 2699 C CD  . LYS B 2 45  ? 104.844 143.426 51.900  1.00 109.24 ? 45  LYS D CD  1 
ATOM 2700 C CE  . LYS B 2 45  ? 104.468 144.896 51.983  1.00 109.24 ? 45  LYS D CE  1 
ATOM 2701 N NZ  . LYS B 2 45  ? 104.477 145.555 50.649  1.00 109.24 ? 45  LYS D NZ  1 
ATOM 2702 N N   . ASN B 2 46  ? 106.354 138.363 54.323  1.00 101.08 ? 46  ASN D N   1 
ATOM 2703 C CA  . ASN B 2 46  ? 106.251 136.913 54.234  1.00 101.08 ? 46  ASN D CA  1 
ATOM 2704 C C   . ASN B 2 46  ? 106.413 136.225 55.583  1.00 101.08 ? 46  ASN D C   1 
ATOM 2705 O O   . ASN B 2 46  ? 106.384 134.992 55.640  1.00 101.08 ? 46  ASN D O   1 
ATOM 2706 C CB  . ASN B 2 46  ? 107.293 136.372 53.249  1.00 101.08 ? 46  ASN D CB  1 
ATOM 2707 C CG  . ASN B 2 46  ? 108.712 136.516 53.761  1.00 101.08 ? 46  ASN D CG  1 
ATOM 2708 O OD1 . ASN B 2 46  ? 108.960 137.194 54.757  1.00 101.08 ? 46  ASN D OD1 1 
ATOM 2709 N ND2 . ASN B 2 46  ? 109.654 135.880 53.075  1.00 101.08 ? 46  ASN D ND2 1 
ATOM 2710 N N   . GLY B 2 47  ? 106.581 136.985 56.664  1.00 92.80  ? 47  GLY D N   1 
ATOM 2711 C CA  . GLY B 2 47  ? 106.723 136.440 57.993  1.00 92.80  ? 47  GLY D CA  1 
ATOM 2712 C C   . GLY B 2 47  ? 108.151 136.350 58.492  1.00 92.80  ? 47  GLY D C   1 
ATOM 2713 O O   . GLY B 2 47  ? 108.360 136.207 59.701  1.00 92.80  ? 47  GLY D O   1 
ATOM 2714 N N   . GLN B 2 48  ? 109.134 136.429 57.600  1.00 93.74  ? 48  GLN D N   1 
ATOM 2715 C CA  . GLN B 2 48  ? 110.526 136.350 58.017  1.00 93.74  ? 48  GLN D CA  1 
ATOM 2716 C C   . GLN B 2 48  ? 110.923 137.590 58.809  1.00 93.74  ? 48  GLN D C   1 
ATOM 2717 O O   . GLN B 2 48  ? 110.543 138.716 58.478  1.00 93.74  ? 48  GLN D O   1 
ATOM 2718 C CB  . GLN B 2 48  ? 111.440 136.193 56.803  1.00 93.74  ? 48  GLN D CB  1 
ATOM 2719 C CG  . GLN B 2 48  ? 111.431 134.799 56.205  1.00 93.74  ? 48  GLN D CG  1 
ATOM 2720 C CD  . GLN B 2 48  ? 112.619 134.541 55.300  1.00 93.74  ? 48  GLN D CD  1 
ATOM 2721 O OE1 . GLN B 2 48  ? 113.376 133.593 55.507  1.00 93.74  ? 48  GLN D OE1 1 
ATOM 2722 N NE2 . GLN B 2 48  ? 112.785 135.382 54.286  1.00 93.74  ? 48  GLN D NE2 1 
ATOM 2723 N N   . LYS B 2 49  ? 111.702 137.373 59.863  1.00 87.16  ? 49  LYS D N   1 
ATOM 2724 C CA  . LYS B 2 49  ? 112.213 138.442 60.709  1.00 87.16  ? 49  LYS D CA  1 
ATOM 2725 C C   . LYS B 2 49  ? 113.707 138.606 60.470  1.00 87.16  ? 49  LYS D C   1 
ATOM 2726 O O   . LYS B 2 49  ? 114.460 137.630 60.512  1.00 87.16  ? 49  LYS D O   1 
ATOM 2727 C CB  . LYS B 2 49  ? 111.955 138.142 62.187  1.00 87.16  ? 49  LYS D CB  1 
ATOM 2728 C CG  . LYS B 2 49  ? 110.488 138.081 62.568  1.00 87.16  ? 49  LYS D CG  1 
ATOM 2729 C CD  . LYS B 2 49  ? 110.296 138.328 64.054  1.00 87.16  ? 49  LYS D CD  1 
ATOM 2730 C CE  . LYS B 2 49  ? 108.826 138.413 64.421  1.00 87.16  ? 49  LYS D CE  1 
ATOM 2731 N NZ  . LYS B 2 49  ? 108.624 138.573 65.886  1.00 87.16  ? 49  LYS D NZ  1 
ATOM 2732 N N   . ALA B 2 50  ? 114.134 139.843 60.227  1.00 89.14  ? 50  ALA D N   1 
ATOM 2733 C CA  . ALA B 2 50  ? 115.530 140.141 59.927  1.00 89.14  ? 50  ALA D CA  1 
ATOM 2734 C C   . ALA B 2 50  ? 116.028 141.215 60.880  1.00 89.14  ? 50  ALA D C   1 
ATOM 2735 O O   . ALA B 2 50  ? 115.409 142.275 61.002  1.00 89.14  ? 50  ALA D O   1 
ATOM 2736 C CB  . ALA B 2 50  ? 115.693 140.599 58.476  1.00 89.14  ? 50  ALA D CB  1 
ATOM 2737 N N   . CYS B 2 51  ? 117.140 140.942 61.555  1.00 90.46  ? 51  CYS D N   1 
ATOM 2738 C CA  . CYS B 2 51  ? 117.759 141.952 62.398  1.00 90.46  ? 51  CYS D CA  1 
ATOM 2739 C C   . CYS B 2 51  ? 118.489 142.971 61.532  1.00 90.46  ? 51  CYS D C   1 
ATOM 2740 O O   . CYS B 2 51  ? 118.941 142.657 60.428  1.00 90.46  ? 51  CYS D O   1 
ATOM 2741 C CB  . CYS B 2 51  ? 118.725 141.300 63.383  1.00 90.46  ? 51  CYS D CB  1 
ATOM 2742 S SG  . CYS B 2 51  ? 117.920 140.276 64.629  1.00 90.46  ? 51  CYS D SG  1 
ATOM 2743 N N   . LEU B 2 52  ? 118.599 144.197 62.034  1.00 92.64  ? 52  LEU D N   1 
ATOM 2744 C CA  . LEU B 2 52  ? 119.232 145.291 61.315  1.00 92.64  ? 52  LEU D CA  1 
ATOM 2745 C C   . LEU B 2 52  ? 120.258 145.973 62.208  1.00 92.64  ? 52  LEU D C   1 
ATOM 2746 O O   . LEU B 2 52  ? 120.178 145.903 63.437  1.00 92.64  ? 52  LEU D O   1 
ATOM 2747 C CB  . LEU B 2 52  ? 118.197 146.316 60.842  1.00 92.64  ? 52  LEU D CB  1 
ATOM 2748 C CG  . LEU B 2 52  ? 117.106 145.786 59.912  1.00 92.64  ? 52  LEU D CG  1 
ATOM 2749 C CD1 . LEU B 2 52  ? 116.098 146.873 59.598  1.00 92.64  ? 52  LEU D CD1 1 
ATOM 2750 C CD2 . LEU B 2 52  ? 117.717 145.245 58.635  1.00 92.64  ? 52  LEU D CD2 1 
ATOM 2751 N N   . ASN B 2 53  ? 121.226 146.624 61.580  1.00 96.67  ? 53  ASN D N   1 
ATOM 2752 C CA  . ASN B 2 53  ? 122.263 147.341 62.313  1.00 96.67  ? 53  ASN D CA  1 
ATOM 2753 C C   . ASN B 2 53  ? 121.799 148.757 62.627  1.00 96.67  ? 53  ASN D C   1 
ATOM 2754 O O   . ASN B 2 53  ? 121.577 149.539 61.694  1.00 96.67  ? 53  ASN D O   1 
ATOM 2755 C CB  . ASN B 2 53  ? 123.552 147.381 61.499  1.00 96.67  ? 53  ASN D CB  1 
ATOM 2756 C CG  . ASN B 2 53  ? 124.651 148.165 62.187  1.00 96.67  ? 53  ASN D CG  1 
ATOM 2757 O OD1 . ASN B 2 53  ? 124.528 148.540 63.353  1.00 96.67  ? 53  ASN D OD1 1 
ATOM 2758 N ND2 . ASN B 2 53  ? 125.736 148.417 61.466  1.00 96.67  ? 53  ASN D ND2 1 
ATOM 2759 N N   . PRO B 2 54  ? 121.650 149.139 63.898  1.00 93.04  ? 54  PRO D N   1 
ATOM 2760 C CA  . PRO B 2 54  ? 121.155 150.492 64.195  1.00 93.04  ? 54  PRO D CA  1 
ATOM 2761 C C   . PRO B 2 54  ? 122.044 151.598 63.660  1.00 93.04  ? 54  PRO D C   1 
ATOM 2762 O O   . PRO B 2 54  ? 121.531 152.669 63.312  1.00 93.04  ? 54  PRO D O   1 
ATOM 2763 C CB  . PRO B 2 54  ? 121.091 150.514 65.728  1.00 93.04  ? 54  PRO D CB  1 
ATOM 2764 C CG  . PRO B 2 54  ? 122.035 149.458 66.166  1.00 93.04  ? 54  PRO D CG  1 
ATOM 2765 C CD  . PRO B 2 54  ? 121.968 148.391 65.125  1.00 93.04  ? 54  PRO D CD  1 
ATOM 2766 N N   . ALA B 2 55  ? 123.356 151.381 63.581  1.00 99.60  ? 55  ALA D N   1 
ATOM 2767 C CA  . ALA B 2 55  ? 124.260 152.451 63.179  1.00 99.60  ? 55  ALA D CA  1 
ATOM 2768 C C   . ALA B 2 55  ? 124.161 152.771 61.693  1.00 99.60  ? 55  ALA D C   1 
ATOM 2769 O O   . ALA B 2 55  ? 124.449 153.903 61.290  1.00 99.60  ? 55  ALA D O   1 
ATOM 2770 C CB  . ALA B 2 55  ? 125.700 152.078 63.531  1.00 99.60  ? 55  ALA D CB  1 
ATOM 2771 N N   . SER B 2 56  ? 123.757 151.810 60.874  1.00 105.57 ? 56  SER D N   1 
ATOM 2772 C CA  . SER B 2 56  ? 123.756 152.013 59.435  1.00 105.57 ? 56  SER D CA  1 
ATOM 2773 C C   . SER B 2 56  ? 122.782 153.131 59.060  1.00 105.57 ? 56  SER D C   1 
ATOM 2774 O O   . SER B 2 56  ? 121.671 153.185 59.606  1.00 105.57 ? 56  SER D O   1 
ATOM 2775 C CB  . SER B 2 56  ? 123.368 150.721 58.718  1.00 105.57 ? 56  SER D CB  1 
ATOM 2776 O OG  . SER B 2 56  ? 122.979 150.980 57.381  1.00 105.57 ? 56  SER D OG  1 
ATOM 2777 N N   . PRO B 2 57  ? 123.154 154.036 58.148  1.00 109.83 ? 57  PRO D N   1 
ATOM 2778 C CA  . PRO B 2 57  ? 122.185 155.056 57.709  1.00 109.83 ? 57  PRO D CA  1 
ATOM 2779 C C   . PRO B 2 57  ? 120.953 154.465 57.048  1.00 109.83 ? 57  PRO D C   1 
ATOM 2780 O O   . PRO B 2 57  ? 119.889 155.100 57.036  1.00 109.83 ? 57  PRO D O   1 
ATOM 2781 C CB  . PRO B 2 57  ? 122.999 155.911 56.726  1.00 109.83 ? 57  PRO D CB  1 
ATOM 2782 C CG  . PRO B 2 57  ? 124.423 155.655 57.071  1.00 109.83 ? 57  PRO D CG  1 
ATOM 2783 C CD  . PRO B 2 57  ? 124.477 154.237 57.534  1.00 109.83 ? 57  PRO D CD  1 
ATOM 2784 N N   . MET B 2 58  ? 121.073 153.261 56.487  1.00 114.56 ? 58  MET D N   1 
ATOM 2785 C CA  . MET B 2 58  ? 119.949 152.655 55.783  1.00 114.56 ? 58  MET D CA  1 
ATOM 2786 C C   . MET B 2 58  ? 118.769 152.442 56.721  1.00 114.56 ? 58  MET D C   1 
ATOM 2787 O O   . MET B 2 58  ? 117.613 152.658 56.341  1.00 114.56 ? 58  MET D O   1 
ATOM 2788 C CB  . MET B 2 58  ? 120.382 151.331 55.154  1.00 114.56 ? 58  MET D CB  1 
ATOM 2789 C CG  . MET B 2 58  ? 119.386 150.764 54.156  1.00 114.56 ? 58  MET D CG  1 
ATOM 2790 S SD  . MET B 2 58  ? 119.256 151.752 52.654  1.00 114.56 ? 58  MET D SD  1 
ATOM 2791 C CE  . MET B 2 58  ? 117.554 152.302 52.754  1.00 114.56 ? 58  MET D CE  1 
ATOM 2792 N N   . VAL B 2 59  ? 119.039 152.005 57.952  1.00 104.68 ? 59  VAL D N   1 
ATOM 2793 C CA  . VAL B 2 59  ? 117.958 151.774 58.907  1.00 104.68 ? 59  VAL D CA  1 
ATOM 2794 C C   . VAL B 2 59  ? 117.233 153.078 59.209  1.00 104.68 ? 59  VAL D C   1 
ATOM 2795 O O   . VAL B 2 59  ? 115.997 153.130 59.246  1.00 104.68 ? 59  VAL D O   1 
ATOM 2796 C CB  . VAL B 2 59  ? 118.507 151.125 60.190  1.00 104.68 ? 59  VAL D CB  1 
ATOM 2797 C CG1 . VAL B 2 59  ? 117.432 151.074 61.262  1.00 104.68 ? 59  VAL D CG1 1 
ATOM 2798 C CG2 . VAL B 2 59  ? 119.034 149.732 59.891  1.00 104.68 ? 59  VAL D CG2 1 
ATOM 2799 N N   . LYS B 2 60  ? 117.992 154.151 59.438  1.00 110.45 ? 60  LYS D N   1 
ATOM 2800 C CA  . LYS B 2 60  ? 117.376 155.442 59.721  1.00 110.45 ? 60  LYS D CA  1 
ATOM 2801 C C   . LYS B 2 60  ? 116.528 155.907 58.545  1.00 110.45 ? 60  LYS D C   1 
ATOM 2802 O O   . LYS B 2 60  ? 115.407 156.397 58.726  1.00 110.45 ? 60  LYS D O   1 
ATOM 2803 C CB  . LYS B 2 60  ? 118.439 156.477 60.056  1.00 30.00  ? 60  LYS D CB  1 
ATOM 2804 N N   . LYS B 2 61  ? 117.051 155.760 57.326  1.00 120.76 ? 61  LYS D N   1 
ATOM 2805 C CA  . LYS B 2 61  ? 116.288 156.164 56.149  1.00 120.76 ? 61  LYS D CA  1 
ATOM 2806 C C   . LYS B 2 61  ? 115.001 155.360 56.033  1.00 120.76 ? 61  LYS D C   1 
ATOM 2807 O O   . LYS B 2 61  ? 113.928 155.915 55.769  1.00 120.76 ? 61  LYS D O   1 
ATOM 2808 C CB  . LYS B 2 61  ? 117.129 156.009 54.891  1.00 30.00  ? 61  LYS D CB  1 
ATOM 2809 N N   . ILE B 2 62  ? 115.088 154.044 56.234  1.00 114.72 ? 62  ILE D N   1 
ATOM 2810 C CA  . ILE B 2 62  ? 113.905 153.196 56.128  1.00 114.72 ? 62  ILE D CA  1 
ATOM 2811 C C   . ILE B 2 62  ? 112.865 153.619 57.153  1.00 114.72 ? 62  ILE D C   1 
ATOM 2812 O O   . ILE B 2 62  ? 111.674 153.740 56.844  1.00 114.72 ? 62  ILE D O   1 
ATOM 2813 C CB  . ILE B 2 62  ? 114.291 151.716 56.300  1.00 114.72 ? 62  ILE D CB  1 
ATOM 2814 C CG1 . ILE B 2 62  ? 115.108 151.235 55.101  1.00 114.72 ? 62  ILE D CG1 1 
ATOM 2815 C CG2 . ILE B 2 62  ? 113.046 150.860 56.477  1.00 114.72 ? 62  ILE D CG2 1 
ATOM 2816 C CD1 . ILE B 2 62  ? 115.871 149.954 55.361  1.00 114.72 ? 62  ILE D CD1 1 
ATOM 2817 N N   . ILE B 2 63  ? 113.300 153.853 58.391  1.00 105.54 ? 63  ILE D N   1 
ATOM 2818 C CA  . ILE B 2 63  ? 112.358 154.210 59.445  1.00 105.54 ? 63  ILE D CA  1 
ATOM 2819 C C   . ILE B 2 63  ? 111.703 155.551 59.144  1.00 105.54 ? 63  ILE D C   1 
ATOM 2820 O O   . ILE B 2 63  ? 110.493 155.721 59.333  1.00 105.54 ? 63  ILE D O   1 
ATOM 2821 C CB  . ILE B 2 63  ? 113.064 154.211 60.812  1.00 105.54 ? 63  ILE D CB  1 
ATOM 2822 C CG1 . ILE B 2 63  ? 113.104 152.791 61.378  1.00 105.54 ? 63  ILE D CG1 1 
ATOM 2823 C CG2 . ILE B 2 63  ? 112.352 155.138 61.781  1.00 105.54 ? 63  ILE D CG2 1 
ATOM 2824 C CD1 . ILE B 2 63  ? 114.079 152.607 62.516  1.00 105.54 ? 63  ILE D CD1 1 
ATOM 2825 N N   . GLU B 2 64  ? 112.487 156.530 58.685  1.00 117.17 ? 64  GLU D N   1 
ATOM 2826 C CA  . GLU B 2 64  ? 111.918 157.846 58.415  1.00 117.17 ? 64  GLU D CA  1 
ATOM 2827 C C   . GLU B 2 64  ? 110.932 157.785 57.253  1.00 117.17 ? 64  GLU D C   1 
ATOM 2828 O O   . GLU B 2 64  ? 109.867 158.412 57.295  1.00 117.17 ? 64  GLU D O   1 
ATOM 2829 C CB  . GLU B 2 64  ? 113.021 158.854 58.127  1.00 30.00  ? 64  GLU D CB  1 
ATOM 2830 N N   . LYS B 2 65  ? 111.265 157.026 56.204  1.00 120.02 ? 65  LYS D N   1 
ATOM 2831 C CA  . LYS B 2 65  ? 110.328 156.865 55.097  1.00 120.02 ? 65  LYS D CA  1 
ATOM 2832 C C   . LYS B 2 65  ? 109.052 156.175 55.559  1.00 120.02 ? 65  LYS D C   1 
ATOM 2833 O O   . LYS B 2 65  ? 107.948 156.560 55.156  1.00 120.02 ? 65  LYS D O   1 
ATOM 2834 C CB  . LYS B 2 65  ? 110.975 156.086 53.962  1.00 30.00  ? 65  LYS D CB  1 
ATOM 2835 N N   . MET B 2 66  ? 109.181 155.151 56.405  1.00 109.42 ? 66  MET D N   1 
ATOM 2836 C CA  . MET B 2 66  ? 108.001 154.468 56.922  1.00 109.42 ? 66  MET D CA  1 
ATOM 2837 C C   . MET B 2 66  ? 107.124 155.427 57.716  1.00 109.42 ? 66  MET D C   1 
ATOM 2838 O O   . MET B 2 66  ? 105.898 155.448 57.555  1.00 109.42 ? 66  MET D O   1 
ATOM 2839 C CB  . MET B 2 66  ? 108.430 153.289 57.794  1.00 109.42 ? 66  MET D CB  1 
ATOM 2840 C CG  . MET B 2 66  ? 108.610 151.989 57.037  1.00 109.42 ? 66  MET D CG  1 
ATOM 2841 S SD  . MET B 2 66  ? 109.101 150.638 58.122  1.00 109.42 ? 66  MET D SD  1 
ATOM 2842 C CE  . MET B 2 66  ? 107.560 150.308 58.969  1.00 109.42 ? 66  MET D CE  1 
ATOM 2843 N N   . LEU B 2 67  ? 107.740 156.235 58.581  1.00 110.40 ? 67  LEU D N   1 
ATOM 2844 C CA  . LEU B 2 67  ? 106.973 157.187 59.378  1.00 110.40 ? 67  LEU D CA  1 
ATOM 2845 C C   . LEU B 2 67  ? 106.283 158.215 58.492  1.00 110.40 ? 67  LEU D C   1 
ATOM 2846 O O   . LEU B 2 67  ? 105.128 158.579 58.740  1.00 110.40 ? 67  LEU D O   1 
ATOM 2847 C CB  . LEU B 2 67  ? 107.885 157.877 60.390  1.00 110.40 ? 67  LEU D CB  1 
ATOM 2848 C CG  . LEU B 2 67  ? 108.500 156.964 61.450  1.00 110.40 ? 67  LEU D CG  1 
ATOM 2849 C CD1 . LEU B 2 67  ? 109.720 157.616 62.081  1.00 110.40 ? 67  LEU D CD1 1 
ATOM 2850 C CD2 . LEU B 2 67  ? 107.470 156.619 62.510  1.00 110.40 ? 67  LEU D CD2 1 
ATOM 2851 N N   . LYS B 2 68  ? 106.973 158.695 57.456  1.00 121.37 ? 68  LYS D N   1 
ATOM 2852 C CA  . LYS B 2 68  ? 106.381 159.693 56.571  1.00 121.37 ? 68  LYS D CA  1 
ATOM 2853 C C   . LYS B 2 68  ? 105.079 159.183 55.968  1.00 121.37 ? 68  LYS D C   1 
ATOM 2854 O O   . LYS B 2 68  ? 104.112 159.938 55.815  1.00 121.37 ? 68  LYS D O   1 
ATOM 2855 C CB  . LYS B 2 68  ? 107.362 160.079 55.474  1.00 30.00  ? 68  LYS D CB  1 
ATOM 2856 N N   . ASN B 2 69  ? 105.037 157.902 55.619  1.00 116.88 ? 69  ASN D N   1 
ATOM 2857 C CA  . ASN B 2 69  ? 103.833 157.292 55.067  1.00 116.88 ? 69  ASN D CA  1 
ATOM 2858 C C   . ASN B 2 69  ? 103.393 158.006 53.793  1.00 116.88 ? 69  ASN D C   1 
ATOM 2859 O O   . ASN B 2 69  ? 102.554 157.502 53.047  1.00 116.88 ? 69  ASN D O   1 
ATOM 2860 C CB  . ASN B 2 69  ? 102.703 157.312 56.098  1.00 116.88 ? 69  ASN D CB  1 
ATOM 2861 C CG  . ASN B 2 69  ? 101.468 156.575 55.622  1.00 116.88 ? 69  ASN D CG  1 
ATOM 2862 O OD1 . ASN B 2 69  ? 101.558 155.472 55.084  1.00 116.88 ? 69  ASN D OD1 1 
ATOM 2863 N ND2 . ASN B 2 69  ? 100.304 157.184 55.817  1.00 116.88 ? 69  ASN D ND2 1 
ATOM 2864 N N   . CYS C 2 9   ? 93.469  147.806 62.053  1.00 131.26 ? 9   CYS E N   1 
ATOM 2865 C CA  . CYS C 2 9   ? 94.098  148.867 62.829  1.00 131.26 ? 9   CYS E CA  1 
ATOM 2866 C C   . CYS C 2 9   ? 94.047  148.548 64.318  1.00 131.26 ? 9   CYS E C   1 
ATOM 2867 O O   . CYS C 2 9   ? 92.996  148.189 64.848  1.00 131.26 ? 9   CYS E O   1 
ATOM 2868 C CB  . CYS C 2 9   ? 93.414  150.209 62.559  1.00 131.26 ? 9   CYS E CB  1 
ATOM 2869 S SG  . CYS C 2 9   ? 93.081  150.543 60.814  1.00 131.26 ? 9   CYS E SG  1 
ATOM 2870 N N   . GLN C 2 10  ? 95.189  148.679 64.989  1.00 124.38 ? 10  GLN E N   1 
ATOM 2871 C CA  . GLN C 2 10  ? 95.282  148.448 66.424  1.00 124.38 ? 10  GLN E CA  1 
ATOM 2872 C C   . GLN C 2 10  ? 95.118  149.723 67.240  1.00 124.38 ? 10  GLN E C   1 
ATOM 2873 O O   . GLN C 2 10  ? 95.251  149.676 68.466  1.00 124.38 ? 10  GLN E O   1 
ATOM 2874 C CB  . GLN C 2 10  ? 96.623  147.789 66.776  1.00 124.38 ? 10  GLN E CB  1 
ATOM 2875 C CG  . GLN C 2 10  ? 97.259  146.980 65.653  1.00 124.38 ? 10  GLN E CG  1 
ATOM 2876 C CD  . GLN C 2 10  ? 96.312  145.953 65.063  1.00 124.38 ? 10  GLN E CD  1 
ATOM 2877 O OE1 . GLN C 2 10  ? 95.816  145.073 65.766  1.00 124.38 ? 10  GLN E OE1 1 
ATOM 2878 N NE2 . GLN C 2 10  ? 96.058  146.060 63.764  1.00 124.38 ? 10  GLN E NE2 1 
ATOM 2879 N N   . CYS C 2 11  ? 94.840  150.856 66.597  1.00 128.46 ? 11  CYS E N   1 
ATOM 2880 C CA  . CYS C 2 11  ? 94.728  152.136 67.283  1.00 128.46 ? 11  CYS E CA  1 
ATOM 2881 C C   . CYS C 2 11  ? 93.514  152.892 66.768  1.00 128.46 ? 11  CYS E C   1 
ATOM 2882 O O   . CYS C 2 11  ? 93.266  152.925 65.558  1.00 128.46 ? 11  CYS E O   1 
ATOM 2883 C CB  . CYS C 2 11  ? 95.993  152.972 67.081  1.00 128.46 ? 11  CYS E CB  1 
ATOM 2884 S SG  . CYS C 2 11  ? 97.486  152.154 67.662  1.00 128.46 ? 11  CYS E SG  1 
ATOM 2885 N N   . LEU C 2 12  ? 92.762  153.496 67.688  1.00 132.44 ? 12  LEU E N   1 
ATOM 2886 C CA  . LEU C 2 12  ? 91.626  154.345 67.351  1.00 132.44 ? 12  LEU E CA  1 
ATOM 2887 C C   . LEU C 2 12  ? 91.938  155.823 67.548  1.00 132.44 ? 12  LEU E C   1 
ATOM 2888 O O   . LEU C 2 12  ? 91.774  156.620 66.620  1.00 132.44 ? 12  LEU E O   1 
ATOM 2889 C CB  . LEU C 2 12  ? 90.412  153.949 68.177  1.00 30.00  ? 12  LEU E CB  1 
ATOM 2890 N N   . GLN C 2 13  ? 92.362  156.160 68.764  1.00 122.39 ? 13  GLN E N   1 
ATOM 2891 C CA  . GLN C 2 13  ? 92.778  157.556 69.036  1.00 122.39 ? 13  GLN E CA  1 
ATOM 2892 C C   . GLN C 2 13  ? 94.181  157.501 69.655  1.00 122.39 ? 13  GLN E C   1 
ATOM 2893 O O   . GLN C 2 13  ? 94.448  156.581 70.462  1.00 122.39 ? 13  GLN E O   1 
ATOM 2894 C CB  . GLN C 2 13  ? 91.791  158.262 69.953  1.00 30.00  ? 13  GLN E CB  1 
ATOM 2895 N N   . THR C 2 14  ? 95.048  158.427 69.252  1.00 113.74 ? 14  THR E N   1 
ATOM 2896 C CA  . THR C 2 14  ? 96.415  158.442 69.748  1.00 113.74 ? 14  THR E CA  1 
ATOM 2897 C C   . THR C 2 14  ? 96.475  159.014 71.162  1.00 113.74 ? 14  THR E C   1 
ATOM 2898 O O   . THR C 2 14  ? 95.590  159.751 71.606  1.00 113.74 ? 14  THR E O   1 
ATOM 2899 C CB  . THR C 2 14  ? 97.313  159.259 68.819  1.00 113.74 ? 14  THR E CB  1 
ATOM 2900 O OG1 . THR C 2 14  ? 96.751  160.563 68.629  1.00 113.74 ? 14  THR E OG1 1 
ATOM 2901 C CG2 . THR C 2 14  ? 97.454  158.566 67.471  1.00 113.74 ? 14  THR E CG2 1 
ATOM 2902 N N   . LEU C 2 15  ? 97.540  158.657 71.873  1.00 110.87 ? 15  LEU E N   1 
ATOM 2903 C CA  . LEU C 2 15  ? 97.769  159.096 73.239  1.00 110.87 ? 15  LEU E CA  1 
ATOM 2904 C C   . LEU C 2 15  ? 98.845  160.174 73.276  1.00 110.87 ? 15  LEU E C   1 
ATOM 2905 O O   . LEU C 2 15  ? 99.502  160.467 72.273  1.00 110.87 ? 15  LEU E O   1 
ATOM 2906 C CB  . LEU C 2 15  ? 98.186  157.922 74.133  1.00 110.87 ? 15  LEU E CB  1 
ATOM 2907 C CG  . LEU C 2 15  ? 97.428  156.608 73.944  1.00 110.87 ? 15  LEU E CG  1 
ATOM 2908 C CD1 . LEU C 2 15  ? 97.752  155.650 75.075  1.00 110.87 ? 15  LEU E CD1 1 
ATOM 2909 C CD2 . LEU C 2 15  ? 95.931  156.850 73.865  1.00 110.87 ? 15  LEU E CD2 1 
ATOM 2910 N N   . GLN C 2 16  ? 99.013  160.766 74.456  1.00 113.69 ? 16  GLN E N   1 
ATOM 2911 C CA  . GLN C 2 16  ? 100.020 161.791 74.682  1.00 113.69 ? 16  GLN E CA  1 
ATOM 2912 C C   . GLN C 2 16  ? 100.494 161.711 76.126  1.00 113.69 ? 16  GLN E C   1 
ATOM 2913 O O   . GLN C 2 16  ? 99.846  161.104 76.981  1.00 113.69 ? 16  GLN E O   1 
ATOM 2914 C CB  . GLN C 2 16  ? 99.480  163.195 74.377  1.00 113.69 ? 16  GLN E CB  1 
ATOM 2915 C CG  . GLN C 2 16  ? 99.005  163.377 72.945  1.00 113.69 ? 16  GLN E CG  1 
ATOM 2916 C CD  . GLN C 2 16  ? 98.479  164.771 72.678  1.00 113.69 ? 16  GLN E CD  1 
ATOM 2917 O OE1 . GLN C 2 16  ? 98.449  165.618 73.571  1.00 113.69 ? 16  GLN E OE1 1 
ATOM 2918 N NE2 . GLN C 2 16  ? 98.058  165.017 71.443  1.00 113.69 ? 16  GLN E NE2 1 
ATOM 2919 N N   . GLY C 2 17  ? 101.638 162.334 76.387  1.00 109.83 ? 17  GLY E N   1 
ATOM 2920 C CA  . GLY C 2 17  ? 102.231 162.331 77.707  1.00 109.83 ? 17  GLY E CA  1 
ATOM 2921 C C   . GLY C 2 17  ? 103.242 161.235 77.959  1.00 109.83 ? 17  GLY E C   1 
ATOM 2922 O O   . GLY C 2 17  ? 103.588 160.995 79.121  1.00 109.83 ? 17  GLY E O   1 
ATOM 2923 N N   . ILE C 2 18  ? 103.723 160.565 76.917  1.00 104.98 ? 18  ILE E N   1 
ATOM 2924 C CA  . ILE C 2 18  ? 104.666 159.462 77.061  1.00 104.98 ? 18  ILE E CA  1 
ATOM 2925 C C   . ILE C 2 18  ? 106.078 160.037 77.017  1.00 104.98 ? 18  ILE E C   1 
ATOM 2926 O O   . ILE C 2 18  ? 106.515 160.557 75.988  1.00 104.98 ? 18  ILE E O   1 
ATOM 2927 C CB  . ILE C 2 18  ? 104.465 158.406 75.967  1.00 104.98 ? 18  ILE E CB  1 
ATOM 2928 C CG1 . ILE C 2 18  ? 102.991 157.997 75.874  1.00 104.98 ? 18  ILE E CG1 1 
ATOM 2929 C CG2 . ILE C 2 18  ? 105.341 157.194 76.231  1.00 104.98 ? 18  ILE E CG2 1 
ATOM 2930 C CD1 . ILE C 2 18  ? 102.436 157.366 77.135  1.00 104.98 ? 18  ILE E CD1 1 
ATOM 2931 N N   . HIS C 2 19  ? 106.792 159.942 78.136  1.00 113.99 ? 19  HIS E N   1 
ATOM 2932 C CA  . HIS C 2 19  ? 108.179 160.372 78.186  1.00 113.99 ? 19  HIS E CA  1 
ATOM 2933 C C   . HIS C 2 19  ? 109.105 159.236 77.763  1.00 113.99 ? 19  HIS E C   1 
ATOM 2934 O O   . HIS C 2 19  ? 108.804 158.053 77.945  1.00 113.99 ? 19  HIS E O   1 
ATOM 2935 C CB  . HIS C 2 19  ? 108.553 160.842 79.592  1.00 113.99 ? 19  HIS E CB  1 
ATOM 2936 C CG  . HIS C 2 19  ? 107.614 161.858 80.162  1.00 113.99 ? 19  HIS E CG  1 
ATOM 2937 N ND1 . HIS C 2 19  ? 107.357 163.063 79.544  1.00 113.99 ? 19  HIS E ND1 1 
ATOM 2938 C CD2 . HIS C 2 19  ? 106.875 161.852 81.296  1.00 113.99 ? 19  HIS E CD2 1 
ATOM 2939 C CE1 . HIS C 2 19  ? 106.497 163.754 80.272  1.00 113.99 ? 19  HIS E CE1 1 
ATOM 2940 N NE2 . HIS C 2 19  ? 106.189 163.041 81.340  1.00 113.99 ? 19  HIS E NE2 1 
ATOM 2941 N N   . LEU C 2 20  ? 110.255 159.611 77.201  1.00 106.16 ? 20  LEU E N   1 
ATOM 2942 C CA  . LEU C 2 20  ? 111.237 158.617 76.788  1.00 106.16 ? 20  LEU E CA  1 
ATOM 2943 C C   . LEU C 2 20  ? 111.731 157.765 77.948  1.00 106.16 ? 20  LEU E C   1 
ATOM 2944 O O   . LEU C 2 20  ? 112.234 156.662 77.711  1.00 106.16 ? 20  LEU E O   1 
ATOM 2945 C CB  . LEU C 2 20  ? 112.427 159.305 76.113  1.00 106.16 ? 20  LEU E CB  1 
ATOM 2946 C CG  . LEU C 2 20  ? 113.506 158.384 75.532  1.00 106.16 ? 20  LEU E CG  1 
ATOM 2947 C CD1 . LEU C 2 20  ? 112.968 157.564 74.370  1.00 106.16 ? 20  LEU E CD1 1 
ATOM 2948 C CD2 . LEU C 2 20  ? 114.712 159.196 75.097  1.00 106.16 ? 20  LEU E CD2 1 
ATOM 2949 N N   . LYS C 2 21  ? 111.608 158.244 79.183  1.00 109.85 ? 21  LYS E N   1 
ATOM 2950 C CA  . LYS C 2 21  ? 112.031 157.481 80.347  1.00 109.85 ? 21  LYS E CA  1 
ATOM 2951 C C   . LYS C 2 21  ? 111.076 156.347 80.693  1.00 109.85 ? 21  LYS E C   1 
ATOM 2952 O O   . LYS C 2 21  ? 111.441 155.475 81.488  1.00 109.85 ? 21  LYS E O   1 
ATOM 2953 C CB  . LYS C 2 21  ? 112.193 158.407 81.543  1.00 30.00  ? 21  LYS E CB  1 
ATOM 2954 N N   . ASN C 2 22  ? 109.872 156.336 80.122  1.00 101.09 ? 22  ASN E N   1 
ATOM 2955 C CA  . ASN C 2 22  ? 108.900 155.285 80.377  1.00 101.09 ? 22  ASN E CA  1 
ATOM 2956 C C   . ASN C 2 22  ? 108.694 154.349 79.196  1.00 101.09 ? 22  ASN E C   1 
ATOM 2957 O O   . ASN C 2 22  ? 108.002 153.339 79.347  1.00 101.09 ? 22  ASN E O   1 
ATOM 2958 C CB  . ASN C 2 22  ? 107.546 155.895 80.765  1.00 101.09 ? 22  ASN E CB  1 
ATOM 2959 C CG  . ASN C 2 22  ? 107.662 156.900 81.889  1.00 101.09 ? 22  ASN E CG  1 
ATOM 2960 O OD1 . ASN C 2 22  ? 107.294 158.064 81.738  1.00 101.09 ? 22  ASN E OD1 1 
ATOM 2961 N ND2 . ASN C 2 22  ? 108.179 156.454 83.028  1.00 101.09 ? 22  ASN E ND2 1 
ATOM 2962 N N   . ILE C 2 23  ? 109.267 154.651 78.035  1.00 91.15  ? 23  ILE E N   1 
ATOM 2963 C CA  . ILE C 2 23  ? 109.116 153.814 76.852  1.00 91.15  ? 23  ILE E CA  1 
ATOM 2964 C C   . ILE C 2 23  ? 110.134 152.689 76.914  1.00 91.15  ? 23  ILE E C   1 
ATOM 2965 O O   . ILE C 2 23  ? 111.311 152.920 77.212  1.00 91.15  ? 23  ILE E O   1 
ATOM 2966 C CB  . ILE C 2 23  ? 109.293 154.636 75.565  1.00 91.15  ? 23  ILE E CB  1 
ATOM 2967 C CG1 . ILE C 2 23  ? 108.179 155.670 75.431  1.00 91.15  ? 23  ILE E CG1 1 
ATOM 2968 C CG2 . ILE C 2 23  ? 109.299 153.725 74.356  1.00 91.15  ? 23  ILE E CG2 1 
ATOM 2969 C CD1 . ILE C 2 23  ? 108.474 156.740 74.408  1.00 91.15  ? 23  ILE E CD1 1 
ATOM 2970 N N   . GLN C 2 24  ? 109.681 151.469 76.635  1.00 76.51  ? 24  GLN E N   1 
ATOM 2971 C CA  . GLN C 2 24  ? 110.578 150.326 76.545  1.00 76.51  ? 24  GLN E CA  1 
ATOM 2972 C C   . GLN C 2 24  ? 110.877 149.959 75.099  1.00 76.51  ? 24  GLN E C   1 
ATOM 2973 O O   . GLN C 2 24  ? 112.012 149.597 74.776  1.00 76.51  ? 24  GLN E O   1 
ATOM 2974 C CB  . GLN C 2 24  ? 109.974 149.125 77.272  1.00 76.51  ? 24  GLN E CB  1 
ATOM 2975 C CG  . GLN C 2 24  ? 110.897 147.931 77.371  1.00 76.51  ? 24  GLN E CG  1 
ATOM 2976 C CD  . GLN C 2 24  ? 110.203 146.717 77.941  1.00 76.51  ? 24  GLN E CD  1 
ATOM 2977 O OE1 . GLN C 2 24  ? 109.092 146.380 77.539  1.00 76.51  ? 24  GLN E OE1 1 
ATOM 2978 N NE2 . GLN C 2 24  ? 110.850 146.057 78.891  1.00 76.51  ? 24  GLN E NE2 1 
ATOM 2979 N N   . SER C 2 25  ? 109.882 150.046 74.221  1.00 79.10  ? 25  SER E N   1 
ATOM 2980 C CA  . SER C 2 25  ? 110.098 149.734 72.814  1.00 79.10  ? 25  SER E CA  1 
ATOM 2981 C C   . SER C 2 25  ? 109.053 150.450 71.974  1.00 79.10  ? 25  SER E C   1 
ATOM 2982 O O   . SER C 2 25  ? 108.025 150.895 72.483  1.00 79.10  ? 25  SER E O   1 
ATOM 2983 C CB  . SER C 2 25  ? 110.044 148.225 72.562  1.00 79.10  ? 25  SER E CB  1 
ATOM 2984 O OG  . SER C 2 25  ? 108.723 147.732 72.690  1.00 79.10  ? 25  SER E OG  1 
ATOM 2985 N N   . VAL C 2 26  ? 109.329 150.552 70.677  1.00 82.98  ? 26  VAL E N   1 
ATOM 2986 C CA  . VAL C 2 26  ? 108.423 151.174 69.719  1.00 82.98  ? 26  VAL E CA  1 
ATOM 2987 C C   . VAL C 2 26  ? 108.330 150.279 68.494  1.00 82.98  ? 26  VAL E C   1 
ATOM 2988 O O   . VAL C 2 26  ? 109.355 149.829 67.973  1.00 82.98  ? 26  VAL E O   1 
ATOM 2989 C CB  . VAL C 2 26  ? 108.891 152.584 69.316  1.00 82.98  ? 26  VAL E CB  1 
ATOM 2990 C CG1 . VAL C 2 26  ? 108.041 153.115 68.179  1.00 82.98  ? 26  VAL E CG1 1 
ATOM 2991 C CG2 . VAL C 2 26  ? 108.825 153.519 70.501  1.00 82.98  ? 26  VAL E CG2 1 
ATOM 2992 N N   . LYS C 2 27  ? 107.109 150.031 68.031  1.00 86.37  ? 27  LYS E N   1 
ATOM 2993 C CA  . LYS C 2 27  ? 106.852 149.216 66.854  1.00 86.37  ? 27  LYS E CA  1 
ATOM 2994 C C   . LYS C 2 27  ? 106.090 150.052 65.837  1.00 86.37  ? 27  LYS E C   1 
ATOM 2995 O O   . LYS C 2 27  ? 105.038 150.617 66.156  1.00 86.37  ? 27  LYS E O   1 
ATOM 2996 C CB  . LYS C 2 27  ? 106.054 147.966 67.231  1.00 86.37  ? 27  LYS E CB  1 
ATOM 2997 C CG  . LYS C 2 27  ? 105.694 147.057 66.067  1.00 86.37  ? 27  LYS E CG  1 
ATOM 2998 C CD  . LYS C 2 27  ? 104.676 146.011 66.486  1.00 86.37  ? 27  LYS E CD  1 
ATOM 2999 C CE  . LYS C 2 27  ? 104.151 145.237 65.293  1.00 86.37  ? 27  LYS E CE  1 
ATOM 3000 N NZ  . LYS C 2 27  ? 102.956 144.419 65.636  1.00 86.37  ? 27  LYS E NZ  1 
ATOM 3001 N N   . VAL C 2 28  ? 106.614 150.121 64.619  1.00 94.42  ? 28  VAL E N   1 
ATOM 3002 C CA  . VAL C 2 28  ? 106.027 150.916 63.547  1.00 94.42  ? 28  VAL E CA  1 
ATOM 3003 C C   . VAL C 2 28  ? 105.493 149.948 62.503  1.00 94.42  ? 28  VAL E C   1 
ATOM 3004 O O   . VAL C 2 28  ? 106.254 149.158 61.933  1.00 94.42  ? 28  VAL E O   1 
ATOM 3005 C CB  . VAL C 2 28  ? 107.046 151.882 62.931  1.00 94.42  ? 28  VAL E CB  1 
ATOM 3006 C CG1 . VAL C 2 28  ? 106.384 152.746 61.873  1.00 94.42  ? 28  VAL E CG1 1 
ATOM 3007 C CG2 . VAL C 2 28  ? 107.679 152.742 64.010  1.00 94.42  ? 28  VAL E CG2 1 
ATOM 3008 N N   . LYS C 2 29  ? 104.191 150.012 62.241  1.00 106.03 ? 29  LYS E N   1 
ATOM 3009 C CA  . LYS C 2 29  ? 103.537 149.134 61.282  1.00 106.03 ? 29  LYS E CA  1 
ATOM 3010 C C   . LYS C 2 29  ? 103.048 149.958 60.099  1.00 106.03 ? 29  LYS E C   1 
ATOM 3011 O O   . LYS C 2 29  ? 102.325 150.945 60.278  1.00 106.03 ? 29  LYS E O   1 
ATOM 3012 C CB  . LYS C 2 29  ? 102.374 148.385 61.933  1.00 106.03 ? 29  LYS E CB  1 
ATOM 3013 C CG  . LYS C 2 29  ? 101.999 147.102 61.214  1.00 106.03 ? 29  LYS E CG  1 
ATOM 3014 C CD  . LYS C 2 29  ? 100.881 146.362 61.927  1.00 106.03 ? 29  LYS E CD  1 
ATOM 3015 C CE  . LYS C 2 29  ? 100.680 144.976 61.337  1.00 106.03 ? 29  LYS E CE  1 
ATOM 3016 N NZ  . LYS C 2 29  ? 99.858  144.103 62.216  1.00 106.03 ? 29  LYS E NZ  1 
ATOM 3017 N N   . SER C 2 30  ? 103.448 149.546 58.900  1.00 103.99 ? 30  SER E N   1 
ATOM 3018 C CA  . SER C 2 30  ? 103.143 150.267 57.678  1.00 103.99 ? 30  SER E CA  1 
ATOM 3019 C C   . SER C 2 30  ? 101.763 149.891 57.152  1.00 103.99 ? 30  SER E C   1 
ATOM 3020 O O   . SER C 2 30  ? 101.177 148.892 57.574  1.00 103.99 ? 30  SER E O   1 
ATOM 3021 C CB  . SER C 2 30  ? 104.200 149.968 56.621  1.00 103.99 ? 30  SER E CB  1 
ATOM 3022 O OG  . SER C 2 30  ? 104.230 148.586 56.316  1.00 103.99 ? 30  SER E OG  1 
ATOM 3023 N N   . PRO C 2 31  ? 101.221 150.677 56.221  1.00 107.77 ? 31  PRO E N   1 
ATOM 3024 C CA  . PRO C 2 31  ? 99.891  150.371 55.685  1.00 107.77 ? 31  PRO E CA  1 
ATOM 3025 C C   . PRO C 2 31  ? 99.864  149.026 54.977  1.00 107.77 ? 31  PRO E C   1 
ATOM 3026 O O   . PRO C 2 31  ? 100.856 148.567 54.408  1.00 107.77 ? 31  PRO E O   1 
ATOM 3027 C CB  . PRO C 2 31  ? 99.626  151.521 54.705  1.00 107.77 ? 31  PRO E CB  1 
ATOM 3028 C CG  . PRO C 2 31  ? 100.563 152.605 55.117  1.00 107.77 ? 31  PRO E CG  1 
ATOM 3029 C CD  . PRO C 2 31  ? 101.778 151.899 55.620  1.00 107.77 ? 31  PRO E CD  1 
ATOM 3030 N N   . GLY C 2 32  ? 98.695  148.394 55.019  1.00 116.31 ? 32  GLY E N   1 
ATOM 3031 C CA  . GLY C 2 32  ? 98.497  147.107 54.400  1.00 116.31 ? 32  GLY E CA  1 
ATOM 3032 C C   . GLY C 2 32  ? 97.067  146.633 54.553  1.00 116.31 ? 32  GLY E C   1 
ATOM 3033 O O   . GLY C 2 32  ? 96.176  147.398 54.936  1.00 116.31 ? 32  GLY E O   1 
ATOM 3034 N N   . PRO C 2 33  ? 96.815  145.358 54.251  1.00 120.17 ? 33  PRO E N   1 
ATOM 3035 C CA  . PRO C 2 33  ? 95.449  144.835 54.418  1.00 120.17 ? 33  PRO E CA  1 
ATOM 3036 C C   . PRO C 2 33  ? 94.939  144.954 55.841  1.00 120.17 ? 33  PRO E C   1 
ATOM 3037 O O   . PRO C 2 33  ? 93.731  145.128 56.046  1.00 120.17 ? 33  PRO E O   1 
ATOM 3038 C CB  . PRO C 2 33  ? 95.574  143.368 53.978  1.00 120.17 ? 33  PRO E CB  1 
ATOM 3039 C CG  . PRO C 2 33  ? 97.031  143.052 54.049  1.00 120.17 ? 33  PRO E CG  1 
ATOM 3040 C CD  . PRO C 2 33  ? 97.754  144.329 53.775  1.00 120.17 ? 33  PRO E CD  1 
ATOM 3041 N N   . HIS C 2 34  ? 95.826  144.863 56.834  1.00 120.62 ? 34  HIS E N   1 
ATOM 3042 C CA  . HIS C 2 34  ? 95.400  145.010 58.222  1.00 120.62 ? 34  HIS E CA  1 
ATOM 3043 C C   . HIS C 2 34  ? 94.827  146.398 58.482  1.00 120.62 ? 34  HIS E C   1 
ATOM 3044 O O   . HIS C 2 34  ? 93.794  146.534 59.148  1.00 120.62 ? 34  HIS E O   1 
ATOM 3045 C CB  . HIS C 2 34  ? 96.577  144.738 59.158  1.00 120.62 ? 34  HIS E CB  1 
ATOM 3046 C CG  . HIS C 2 34  ? 97.785  145.571 58.864  1.00 120.62 ? 34  HIS E CG  1 
ATOM 3047 N ND1 . HIS C 2 34  ? 98.679  145.258 57.863  1.00 120.62 ? 34  HIS E ND1 1 
ATOM 3048 C CD2 . HIS C 2 34  ? 98.243  146.710 59.435  1.00 120.62 ? 34  HIS E CD2 1 
ATOM 3049 C CE1 . HIS C 2 34  ? 99.637  146.167 57.831  1.00 120.62 ? 34  HIS E CE1 1 
ATOM 3050 N NE2 . HIS C 2 34  ? 99.396  147.059 58.775  1.00 120.62 ? 34  HIS E NE2 1 
ATOM 3051 N N   . CYS C 2 35  ? 95.479  147.438 57.966  1.00 121.57 ? 35  CYS E N   1 
ATOM 3052 C CA  . CYS C 2 35  ? 95.046  148.809 58.207  1.00 121.57 ? 35  CYS E CA  1 
ATOM 3053 C C   . CYS C 2 35  ? 95.572  149.696 57.090  1.00 121.57 ? 35  CYS E C   1 
ATOM 3054 O O   . CYS C 2 35  ? 96.667  149.457 56.572  1.00 121.57 ? 35  CYS E O   1 
ATOM 3055 C CB  . CYS C 2 35  ? 95.544  149.312 59.565  1.00 121.57 ? 35  CYS E CB  1 
ATOM 3056 S SG  . CYS C 2 35  ? 94.910  150.938 60.027  1.00 121.57 ? 35  CYS E SG  1 
ATOM 3057 N N   . ALA C 2 36  ? 94.794  150.715 56.727  1.00 111.45 ? 36  ALA E N   1 
ATOM 3058 C CA  . ALA C 2 36  ? 95.184  151.637 55.669  1.00 111.45 ? 36  ALA E CA  1 
ATOM 3059 C C   . ALA C 2 36  ? 96.019  152.806 56.174  1.00 111.45 ? 36  ALA E C   1 
ATOM 3060 O O   . ALA C 2 36  ? 96.520  153.583 55.354  1.00 111.45 ? 36  ALA E O   1 
ATOM 3061 C CB  . ALA C 2 36  ? 93.941  152.171 54.956  1.00 111.45 ? 36  ALA E CB  1 
ATOM 3062 N N   . GLN C 2 37  ? 96.178  152.954 57.485  1.00 114.19 ? 37  GLN E N   1 
ATOM 3063 C CA  . GLN C 2 37  ? 96.938  154.049 58.068  1.00 114.19 ? 37  GLN E CA  1 
ATOM 3064 C C   . GLN C 2 37  ? 98.120  153.507 58.861  1.00 114.19 ? 37  GLN E C   1 
ATOM 3065 O O   . GLN C 2 37  ? 97.995  152.532 59.608  1.00 114.19 ? 37  GLN E O   1 
ATOM 3066 C CB  . GLN C 2 37  ? 96.047  154.910 58.951  1.00 30.00  ? 37  GLN E CB  1 
ATOM 3067 N N   . THR C 2 38  ? 99.269  154.153 58.693  1.00 109.18 ? 38  THR E N   1 
ATOM 3068 C CA  . THR C 2 38  ? 100.459 153.775 59.440  1.00 109.18 ? 38  THR E CA  1 
ATOM 3069 C C   . THR C 2 38  ? 100.210 153.917 60.936  1.00 109.18 ? 38  THR E C   1 
ATOM 3070 O O   . THR C 2 38  ? 99.568  154.866 61.393  1.00 109.18 ? 38  THR E O   1 
ATOM 3071 C CB  . THR C 2 38  ? 101.645 154.643 59.028  1.00 109.18 ? 38  THR E CB  1 
ATOM 3072 O OG1 . THR C 2 38  ? 101.979 154.386 57.659  1.00 109.18 ? 38  THR E OG1 1 
ATOM 3073 C CG2 . THR C 2 38  ? 102.850 154.352 59.905  1.00 109.18 ? 38  THR E CG2 1 
ATOM 3074 N N   . GLU C 2 39  ? 100.730 152.961 61.703  1.00 109.43 ? 39  GLU E N   1 
ATOM 3075 C CA  . GLU C 2 39  ? 100.500 152.919 63.139  1.00 109.43 ? 39  GLU E CA  1 
ATOM 3076 C C   . GLU C 2 39  ? 101.827 152.848 63.876  1.00 109.43 ? 39  GLU E C   1 
ATOM 3077 O O   . GLU C 2 39  ? 102.799 152.280 63.371  1.00 109.43 ? 39  GLU E O   1 
ATOM 3078 C CB  . GLU C 2 39  ? 99.630  151.719 63.528  1.00 109.43 ? 39  GLU E CB  1 
ATOM 3079 C CG  . GLU C 2 39  ? 98.224  151.764 62.955  1.00 109.43 ? 39  GLU E CG  1 
ATOM 3080 C CD  . GLU C 2 39  ? 97.233  150.964 63.778  1.00 109.43 ? 39  GLU E CD  1 
ATOM 3081 O OE1 . GLU C 2 39  ? 97.413  149.734 63.895  1.00 109.43 ? 39  GLU E OE1 1 
ATOM 3082 O OE2 . GLU C 2 39  ? 96.272  151.562 64.307  1.00 109.43 ? 39  GLU E OE2 1 
ATOM 3083 N N   . VAL C 2 40  ? 101.863 153.436 65.067  1.00 97.02  ? 40  VAL E N   1 
ATOM 3084 C CA  . VAL C 2 40  ? 103.016 153.364 65.955  1.00 97.02  ? 40  VAL E CA  1 
ATOM 3085 C C   . VAL C 2 40  ? 102.509 152.971 67.333  1.00 97.02  ? 40  VAL E C   1 
ATOM 3086 O O   . VAL C 2 40  ? 101.648 153.655 67.902  1.00 97.02  ? 40  VAL E O   1 
ATOM 3087 C CB  . VAL C 2 40  ? 103.783 154.693 66.009  1.00 97.02  ? 40  VAL E CB  1 
ATOM 3088 C CG1 . VAL C 2 40  ? 104.972 154.579 66.948  1.00 97.02  ? 40  VAL E CG1 1 
ATOM 3089 C CG2 . VAL C 2 40  ? 104.230 155.101 64.616  1.00 97.02  ? 40  VAL E CG2 1 
ATOM 3090 N N   . ILE C 2 41  ? 103.038 151.876 67.867  1.00 89.28  ? 41  ILE E N   1 
ATOM 3091 C CA  . ILE C 2 41  ? 102.611 151.333 69.151  1.00 89.28  ? 41  ILE E CA  1 
ATOM 3092 C C   . ILE C 2 41  ? 103.838 151.231 70.040  1.00 89.28  ? 41  ILE E C   1 
ATOM 3093 O O   . ILE C 2 41  ? 104.802 150.537 69.697  1.00 89.28  ? 41  ILE E O   1 
ATOM 3094 C CB  . ILE C 2 41  ? 101.933 149.964 68.991  1.00 89.28  ? 41  ILE E CB  1 
ATOM 3095 C CG1 . ILE C 2 41  ? 100.720 150.072 68.065  1.00 89.28  ? 41  ILE E CG1 1 
ATOM 3096 C CG2 . ILE C 2 41  ? 101.518 149.412 70.343  1.00 89.28  ? 41  ILE E CG2 1 
ATOM 3097 C CD1 . ILE C 2 41  ? 100.316 148.758 67.443  1.00 89.28  ? 41  ILE E CD1 1 
ATOM 3098 N N   . ALA C 2 42  ? 103.807 151.916 71.174  1.00 84.37  ? 42  ALA E N   1 
ATOM 3099 C CA  . ALA C 2 42  ? 104.922 151.934 72.104  1.00 84.37  ? 42  ALA E CA  1 
ATOM 3100 C C   . ALA C 2 42  ? 104.597 151.083 73.321  1.00 84.37  ? 42  ALA E C   1 
ATOM 3101 O O   . ALA C 2 42  ? 103.553 151.255 73.955  1.00 84.37  ? 42  ALA E O   1 
ATOM 3102 C CB  . ALA C 2 42  ? 105.246 153.363 72.540  1.00 84.37  ? 42  ALA E CB  1 
ATOM 3103 N N   . THR C 2 43  ? 105.497 150.163 73.638  1.00 80.05  ? 43  THR E N   1 
ATOM 3104 C CA  . THR C 2 43  ? 105.401 149.346 74.837  1.00 80.05  ? 43  THR E CA  1 
ATOM 3105 C C   . THR C 2 43  ? 106.186 150.034 75.944  1.00 80.05  ? 43  THR E C   1 
ATOM 3106 O O   . THR C 2 43  ? 107.401 150.227 75.818  1.00 80.05  ? 43  THR E O   1 
ATOM 3107 C CB  . THR C 2 43  ? 105.940 147.939 74.588  1.00 80.05  ? 43  THR E CB  1 
ATOM 3108 O OG1 . THR C 2 43  ? 105.160 147.299 73.573  1.00 80.05  ? 43  THR E OG1 1 
ATOM 3109 C CG2 . THR C 2 43  ? 105.888 147.113 75.860  1.00 80.05  ? 43  THR E CG2 1 
ATOM 3110 N N   . LEU C 2 44  ? 105.486 150.413 77.010  1.00 88.80  ? 44  LEU E N   1 
ATOM 3111 C CA  . LEU C 2 44  ? 106.087 151.076 78.153  1.00 88.80  ? 44  LEU E CA  1 
ATOM 3112 C C   . LEU C 2 44  ? 106.674 150.049 79.117  1.00 88.80  ? 44  LEU E C   1 
ATOM 3113 O O   . LEU C 2 44  ? 106.404 148.849 79.035  1.00 88.80  ? 44  LEU E O   1 
ATOM 3114 C CB  . LEU C 2 44  ? 105.054 151.943 78.868  1.00 88.80  ? 44  LEU E CB  1 
ATOM 3115 C CG  . LEU C 2 44  ? 104.241 152.887 77.981  1.00 88.80  ? 44  LEU E CG  1 
ATOM 3116 C CD1 . LEU C 2 44  ? 103.092 153.497 78.761  1.00 88.80  ? 44  LEU E CD1 1 
ATOM 3117 C CD2 . LEU C 2 44  ? 105.127 153.975 77.406  1.00 88.80  ? 44  LEU E CD2 1 
ATOM 3118 N N   . LYS C 2 45  ? 107.488 150.538 80.052  1.00 80.76  ? 45  LYS E N   1 
ATOM 3119 C CA  . LYS C 2 45  ? 108.161 149.653 80.994  1.00 80.76  ? 45  LYS E CA  1 
ATOM 3120 C C   . LYS C 2 45  ? 107.197 148.952 81.939  1.00 80.76  ? 45  LYS E C   1 
ATOM 3121 O O   . LYS C 2 45  ? 107.594 147.976 82.583  1.00 80.76  ? 45  LYS E O   1 
ATOM 3122 C CB  . LYS C 2 45  ? 109.195 150.437 81.802  1.00 80.76  ? 45  LYS E CB  1 
ATOM 3123 C CG  . LYS C 2 45  ? 110.469 150.734 81.035  1.00 80.76  ? 45  LYS E CG  1 
ATOM 3124 C CD  . LYS C 2 45  ? 111.389 151.661 81.805  1.00 80.76  ? 45  LYS E CD  1 
ATOM 3125 C CE  . LYS C 2 45  ? 112.702 151.869 81.068  1.00 80.76  ? 45  LYS E CE  1 
ATOM 3126 N NZ  . LYS C 2 45  ? 113.574 152.870 81.739  1.00 80.76  ? 45  LYS E NZ  1 
ATOM 3127 N N   . ASN C 2 46  ? 105.955 149.416 82.039  1.00 84.73  ? 46  ASN E N   1 
ATOM 3128 C CA  . ASN C 2 46  ? 104.956 148.797 82.896  1.00 84.73  ? 46  ASN E CA  1 
ATOM 3129 C C   . ASN C 2 46  ? 104.070 147.811 82.148  1.00 84.73  ? 46  ASN E C   1 
ATOM 3130 O O   . ASN C 2 46  ? 103.105 147.304 82.726  1.00 84.73  ? 46  ASN E O   1 
ATOM 3131 C CB  . ASN C 2 46  ? 104.090 149.874 83.555  1.00 84.73  ? 46  ASN E CB  1 
ATOM 3132 C CG  . ASN C 2 46  ? 103.210 150.605 82.563  1.00 84.73  ? 46  ASN E CG  1 
ATOM 3133 O OD1 . ASN C 2 46  ? 103.367 150.460 81.353  1.00 84.73  ? 46  ASN E OD1 1 
ATOM 3134 N ND2 . ASN C 2 46  ? 102.281 151.403 83.073  1.00 84.73  ? 46  ASN E ND2 1 
ATOM 3135 N N   . GLY C 2 47  ? 104.367 147.538 80.878  1.00 84.01  ? 47  GLY E N   1 
ATOM 3136 C CA  . GLY C 2 47  ? 103.638 146.576 80.086  1.00 84.01  ? 47  GLY E CA  1 
ATOM 3137 C C   . GLY C 2 47  ? 102.502 147.160 79.274  1.00 84.01  ? 47  GLY E C   1 
ATOM 3138 O O   . GLY C 2 47  ? 102.065 146.531 78.305  1.00 84.01  ? 47  GLY E O   1 
ATOM 3139 N N   . GLN C 2 48  ? 102.023 148.347 79.634  1.00 95.52  ? 48  GLN E N   1 
ATOM 3140 C CA  . GLN C 2 48  ? 100.924 148.957 78.902  1.00 95.52  ? 48  GLN E CA  1 
ATOM 3141 C C   . GLN C 2 48  ? 101.390 149.414 77.525  1.00 95.52  ? 48  GLN E C   1 
ATOM 3142 O O   . GLN C 2 48  ? 102.545 149.799 77.331  1.00 95.52  ? 48  GLN E O   1 
ATOM 3143 C CB  . GLN C 2 48  ? 100.359 150.141 79.685  1.00 95.52  ? 48  GLN E CB  1 
ATOM 3144 C CG  . GLN C 2 48  ? 99.530  149.743 80.893  1.00 95.52  ? 48  GLN E CG  1 
ATOM 3145 C CD  . GLN C 2 48  ? 98.599  150.849 81.349  1.00 95.52  ? 48  GLN E CD  1 
ATOM 3146 O OE1 . GLN C 2 48  ? 97.386  150.659 81.435  1.00 95.52  ? 48  GLN E OE1 1 
ATOM 3147 N NE2 . GLN C 2 48  ? 99.165  152.015 81.641  1.00 95.52  ? 48  GLN E NE2 1 
ATOM 3148 N N   . LYS C 2 49  ? 100.473 149.375 76.564  1.00 89.49  ? 49  LYS E N   1 
ATOM 3149 C CA  . LYS C 2 49  ? 100.752 149.748 75.185  1.00 89.49  ? 49  LYS E CA  1 
ATOM 3150 C C   . LYS C 2 49  ? 100.036 151.051 74.861  1.00 89.49  ? 49  LYS E C   1 
ATOM 3151 O O   . LYS C 2 49  ? 98.845  151.199 75.154  1.00 89.49  ? 49  LYS E O   1 
ATOM 3152 C CB  . LYS C 2 49  ? 100.313 148.642 74.224  1.00 89.49  ? 49  LYS E CB  1 
ATOM 3153 C CG  . LYS C 2 49  ? 101.073 147.339 74.407  1.00 89.49  ? 49  LYS E CG  1 
ATOM 3154 C CD  . LYS C 2 49  ? 101.149 146.549 73.113  1.00 89.49  ? 49  LYS E CD  1 
ATOM 3155 C CE  . LYS C 2 49  ? 101.988 145.294 73.282  1.00 89.49  ? 49  LYS E CE  1 
ATOM 3156 N NZ  . LYS C 2 49  ? 101.948 144.429 72.072  1.00 89.49  ? 49  LYS E NZ  1 
ATOM 3157 N N   . ALA C 2 50  ? 100.763 151.989 74.258  1.00 93.39  ? 50  ALA E N   1 
ATOM 3158 C CA  . ALA C 2 50  ? 100.254 153.319 73.951  1.00 93.39  ? 50  ALA E CA  1 
ATOM 3159 C C   . ALA C 2 50  ? 100.336 153.549 72.451  1.00 93.39  ? 50  ALA E C   1 
ATOM 3160 O O   . ALA C 2 50  ? 101.363 153.259 71.832  1.00 93.39  ? 50  ALA E O   1 
ATOM 3161 C CB  . ALA C 2 50  ? 101.047 154.390 74.700  1.00 93.39  ? 50  ALA E CB  1 
ATOM 3162 N N   . CYS C 2 51  ? 99.264  154.075 71.869  1.00 104.33 ? 51  CYS E N   1 
ATOM 3163 C CA  . CYS C 2 51  ? 99.253  154.382 70.446  1.00 104.33 ? 51  CYS E CA  1 
ATOM 3164 C C   . CYS C 2 51  ? 99.701  155.820 70.223  1.00 104.33 ? 51  CYS E C   1 
ATOM 3165 O O   . CYS C 2 51  ? 99.225  156.737 70.896  1.00 104.33 ? 51  CYS E O   1 
ATOM 3166 C CB  . CYS C 2 51  ? 97.857  154.164 69.870  1.00 104.33 ? 51  CYS E CB  1 
ATOM 3167 S SG  . CYS C 2 51  ? 97.423  152.426 69.670  1.00 104.33 ? 51  CYS E SG  1 
ATOM 3168 N N   . LEU C 2 52  ? 100.617 156.016 69.276  1.00 98.37  ? 52  LEU E N   1 
ATOM 3169 C CA  . LEU C 2 52  ? 101.185 157.326 68.998  1.00 98.37  ? 52  LEU E CA  1 
ATOM 3170 C C   . LEU C 2 52  ? 100.876 157.733 67.564  1.00 98.37  ? 52  LEU E C   1 
ATOM 3171 O O   . LEU C 2 52  ? 100.762 156.888 66.672  1.00 98.37  ? 52  LEU E O   1 
ATOM 3172 C CB  . LEU C 2 52  ? 102.700 157.327 69.220  1.00 98.37  ? 52  LEU E CB  1 
ATOM 3173 C CG  . LEU C 2 52  ? 103.169 156.760 70.560  1.00 98.37  ? 52  LEU E CG  1 
ATOM 3174 C CD1 . LEU C 2 52  ? 104.681 156.850 70.676  1.00 98.37  ? 52  LEU E CD1 1 
ATOM 3175 C CD2 . LEU C 2 52  ? 102.499 157.476 71.718  1.00 98.37  ? 52  LEU E CD2 1 
ATOM 3176 N N   . ASN C 2 53  ? 100.737 159.034 67.353  1.00 105.77 ? 53  ASN E N   1 
ATOM 3177 C CA  . ASN C 2 53  ? 100.481 159.559 66.017  1.00 105.77 ? 53  ASN E CA  1 
ATOM 3178 C C   . ASN C 2 53  ? 101.764 159.520 65.195  1.00 105.77 ? 53  ASN E C   1 
ATOM 3179 O O   . ASN C 2 53  ? 102.763 160.130 65.599  1.00 105.77 ? 53  ASN E O   1 
ATOM 3180 C CB  . ASN C 2 53  ? 99.955  160.988 66.102  1.00 105.77 ? 53  ASN E CB  1 
ATOM 3181 C CG  . ASN C 2 53  ? 99.858  161.657 64.743  1.00 105.77 ? 53  ASN E CG  1 
ATOM 3182 O OD1 . ASN C 2 53  ? 99.832  160.991 63.709  1.00 105.77 ? 53  ASN E OD1 1 
ATOM 3183 N ND2 . ASN C 2 53  ? 99.806  162.984 64.740  1.00 105.77 ? 53  ASN E ND2 1 
ATOM 3184 N N   . PRO C 2 54  ? 101.795 158.828 64.052  1.00 104.97 ? 54  PRO E N   1 
ATOM 3185 C CA  . PRO C 2 54  ? 103.024 158.820 63.245  1.00 104.97 ? 54  PRO E CA  1 
ATOM 3186 C C   . PRO C 2 54  ? 103.442 160.195 62.760  1.00 104.97 ? 54  PRO E C   1 
ATOM 3187 O O   . PRO C 2 54  ? 104.647 160.453 62.650  1.00 104.97 ? 54  PRO E O   1 
ATOM 3188 C CB  . PRO C 2 54  ? 102.669 157.900 62.070  1.00 104.97 ? 54  PRO E CB  1 
ATOM 3189 C CG  . PRO C 2 54  ? 101.187 157.938 61.992  1.00 104.97 ? 54  PRO E CG  1 
ATOM 3190 C CD  . PRO C 2 54  ? 100.713 158.067 63.404  1.00 104.97 ? 54  PRO E CD  1 
ATOM 3191 N N   . ALA C 2 55  ? 102.492 161.085 62.467  1.00 102.62 ? 55  ALA E N   1 
ATOM 3192 C CA  . ALA C 2 55  ? 102.841 162.407 61.963  1.00 102.62 ? 55  ALA E CA  1 
ATOM 3193 C C   . ALA C 2 55  ? 103.390 163.318 63.052  1.00 102.62 ? 55  ALA E C   1 
ATOM 3194 O O   . ALA C 2 55  ? 104.062 164.305 62.735  1.00 102.62 ? 55  ALA E O   1 
ATOM 3195 C CB  . ALA C 2 55  ? 101.620 163.057 61.312  1.00 102.62 ? 55  ALA E CB  1 
ATOM 3196 N N   . SER C 2 56  ? 103.124 163.016 64.316  1.00 107.80 ? 56  SER E N   1 
ATOM 3197 C CA  . SER C 2 56  ? 103.598 163.867 65.396  1.00 107.80 ? 56  SER E CA  1 
ATOM 3198 C C   . SER C 2 56  ? 105.124 163.841 65.445  1.00 107.80 ? 56  SER E C   1 
ATOM 3199 O O   . SER C 2 56  ? 105.723 162.763 65.329  1.00 107.80 ? 56  SER E O   1 
ATOM 3200 C CB  . SER C 2 56  ? 103.024 163.402 66.732  1.00 107.80 ? 56  SER E CB  1 
ATOM 3201 O OG  . SER C 2 56  ? 103.784 163.907 67.816  1.00 107.80 ? 56  SER E OG  1 
ATOM 3202 N N   . PRO C 2 57  ? 105.788 164.988 65.615  1.00 109.39 ? 57  PRO E N   1 
ATOM 3203 C CA  . PRO C 2 57  ? 107.254 164.964 65.743  1.00 109.39 ? 57  PRO E CA  1 
ATOM 3204 C C   . PRO C 2 57  ? 107.745 164.200 66.959  1.00 109.39 ? 57  PRO E C   1 
ATOM 3205 O O   . PRO C 2 57  ? 108.918 163.812 66.994  1.00 109.39 ? 57  PRO E O   1 
ATOM 3206 C CB  . PRO C 2 57  ? 107.627 166.451 65.831  1.00 109.39 ? 57  PRO E CB  1 
ATOM 3207 C CG  . PRO C 2 57  ? 106.471 167.179 65.244  1.00 109.39 ? 57  PRO E CG  1 
ATOM 3208 C CD  . PRO C 2 57  ? 105.265 166.364 65.578  1.00 109.39 ? 57  PRO E CD  1 
ATOM 3209 N N   . MET C 2 58  ? 106.890 163.981 67.960  1.00 114.81 ? 58  MET E N   1 
ATOM 3210 C CA  . MET C 2 58  ? 107.327 163.281 69.164  1.00 114.81 ? 58  MET E CA  1 
ATOM 3211 C C   . MET C 2 58  ? 107.792 161.867 68.839  1.00 114.81 ? 58  MET E C   1 
ATOM 3212 O O   . MET C 2 58  ? 108.801 161.396 69.378  1.00 114.81 ? 58  MET E O   1 
ATOM 3213 C CB  . MET C 2 58  ? 106.189 163.254 70.186  1.00 114.81 ? 58  MET E CB  1 
ATOM 3214 C CG  . MET C 2 58  ? 106.526 162.569 71.506  1.00 114.81 ? 58  MET E CG  1 
ATOM 3215 S SD  . MET C 2 58  ? 107.502 163.615 72.603  1.00 114.81 ? 58  MET E SD  1 
ATOM 3216 C CE  . MET C 2 58  ? 108.141 162.401 73.753  1.00 114.81 ? 58  MET E CE  1 
ATOM 3217 N N   . VAL C 2 59  ? 107.063 161.171 67.965  1.00 109.09 ? 59  VAL E N   1 
ATOM 3218 C CA  . VAL C 2 59  ? 107.453 159.814 67.594  1.00 109.09 ? 59  VAL E CA  1 
ATOM 3219 C C   . VAL C 2 59  ? 108.812 159.823 66.913  1.00 109.09 ? 59  VAL E C   1 
ATOM 3220 O O   . VAL C 2 59  ? 109.672 158.979 67.195  1.00 109.09 ? 59  VAL E O   1 
ATOM 3221 C CB  . VAL C 2 59  ? 106.378 159.178 66.695  1.00 109.09 ? 59  VAL E CB  1 
ATOM 3222 C CG1 . VAL C 2 59  ? 106.899 157.891 66.075  1.00 109.09 ? 59  VAL E CG1 1 
ATOM 3223 C CG2 . VAL C 2 59  ? 105.106 158.923 67.489  1.00 109.09 ? 59  VAL E CG2 1 
ATOM 3224 N N   . LYS C 2 60  ? 109.023 160.766 65.994  1.00 113.24 ? 60  LYS E N   1 
ATOM 3225 C CA  . LYS C 2 60  ? 110.308 160.856 65.312  1.00 113.24 ? 60  LYS E CA  1 
ATOM 3226 C C   . LYS C 2 60  ? 111.428 161.121 66.308  1.00 113.24 ? 60  LYS E C   1 
ATOM 3227 O O   . LYS C 2 60  ? 112.507 160.524 66.221  1.00 113.24 ? 60  LYS E O   1 
ATOM 3228 C CB  . LYS C 2 60  ? 110.272 161.941 64.246  1.00 30.00  ? 60  LYS E CB  1 
ATOM 3229 N N   . LYS C 2 61  ? 111.187 162.020 67.263  1.00 116.27 ? 61  LYS E N   1 
ATOM 3230 C CA  . LYS C 2 61  ? 112.191 162.301 68.284  1.00 116.27 ? 61  LYS E CA  1 
ATOM 3231 C C   . LYS C 2 61  ? 112.529 161.043 69.070  1.00 116.27 ? 61  LYS E C   1 
ATOM 3232 O O   . LYS C 2 61  ? 113.705 160.717 69.276  1.00 116.27 ? 61  LYS E O   1 
ATOM 3233 C CB  . LYS C 2 61  ? 111.709 163.401 69.217  1.00 30.00  ? 61  LYS E CB  1 
ATOM 3234 N N   . ILE C 2 62  ? 111.502 160.313 69.507  1.00 105.37 ? 62  ILE E N   1 
ATOM 3235 C CA  . ILE C 2 62  ? 111.729 159.107 70.296  1.00 105.37 ? 62  ILE E CA  1 
ATOM 3236 C C   . ILE C 2 62  ? 112.550 158.105 69.498  1.00 105.37 ? 62  ILE E C   1 
ATOM 3237 O O   . ILE C 2 62  ? 113.526 157.532 69.997  1.00 105.37 ? 62  ILE E O   1 
ATOM 3238 C CB  . ILE C 2 62  ? 110.388 158.499 70.740  1.00 105.37 ? 62  ILE E CB  1 
ATOM 3239 C CG1 . ILE C 2 62  ? 109.680 159.425 71.730  1.00 105.37 ? 62  ILE E CG1 1 
ATOM 3240 C CG2 . ILE C 2 62  ? 110.614 157.131 71.362  1.00 105.37 ? 62  ILE E CG2 1 
ATOM 3241 C CD1 . ILE C 2 62  ? 108.195 159.151 71.865  1.00 105.37 ? 62  ILE E CD1 1 
ATOM 3242 N N   . ILE C 2 63  ? 112.167 157.884 68.240  1.00 106.09 ? 63  ILE E N   1 
ATOM 3243 C CA  . ILE C 2 63  ? 112.820 156.855 67.435  1.00 106.09 ? 63  ILE E CA  1 
ATOM 3244 C C   . ILE C 2 63  ? 114.270 157.233 67.160  1.00 106.09 ? 63  ILE E C   1 
ATOM 3245 O O   . ILE C 2 63  ? 115.179 156.402 67.277  1.00 106.09 ? 63  ILE E O   1 
ATOM 3246 C CB  . ILE C 2 63  ? 112.039 156.618 66.131  1.00 106.09 ? 63  ILE E CB  1 
ATOM 3247 C CG1 . ILE C 2 63  ? 110.635 156.095 66.443  1.00 106.09 ? 63  ILE E CG1 1 
ATOM 3248 C CG2 . ILE C 2 63  ? 112.783 155.633 65.252  1.00 106.09 ? 63  ILE E CG2 1 
ATOM 3249 C CD1 . ILE C 2 63  ? 109.678 156.160 65.273  1.00 106.09 ? 63  ILE E CD1 1 
ATOM 3250 N N   . GLU C 2 64  ? 114.513 158.492 66.786  1.00 114.24 ? 64  GLU E N   1 
ATOM 3251 C CA  . GLU C 2 64  ? 115.879 158.905 66.488  1.00 114.24 ? 64  GLU E CA  1 
ATOM 3252 C C   . GLU C 2 64  ? 116.750 158.852 67.735  1.00 114.24 ? 64  GLU E C   1 
ATOM 3253 O O   . GLU C 2 64  ? 117.923 158.467 67.664  1.00 114.24 ? 64  GLU E O   1 
ATOM 3254 C CB  . GLU C 2 64  ? 115.894 160.306 65.873  1.00 114.24 ? 64  GLU E CB  1 
ATOM 3255 C CG  . GLU C 2 64  ? 115.461 161.419 66.805  1.00 114.24 ? 64  GLU E CG  1 
ATOM 3256 C CD  . GLU C 2 64  ? 115.434 162.768 66.114  1.00 114.24 ? 64  GLU E CD  1 
ATOM 3257 O OE1 . GLU C 2 64  ? 116.497 163.207 65.627  1.00 114.24 ? 64  GLU E OE1 1 
ATOM 3258 O OE2 . GLU C 2 64  ? 114.352 163.387 66.051  1.00 114.24 ? 64  GLU E OE2 1 
ATOM 3259 N N   . LYS C 2 65  ? 116.200 159.232 68.892  1.00 112.40 ? 65  LYS E N   1 
ATOM 3260 C CA  . LYS C 2 65  ? 116.962 159.114 70.130  1.00 112.40 ? 65  LYS E CA  1 
ATOM 3261 C C   . LYS C 2 65  ? 117.298 157.658 70.422  1.00 112.40 ? 65  LYS E C   1 
ATOM 3262 O O   . LYS C 2 65  ? 118.423 157.336 70.821  1.00 112.40 ? 65  LYS E O   1 
ATOM 3263 C CB  . LYS C 2 65  ? 116.193 159.728 71.290  1.00 30.00  ? 65  LYS E CB  1 
ATOM 3264 N N   . MET C 2 66  ? 116.331 156.759 70.222  1.00 97.94  ? 66  MET E N   1 
ATOM 3265 C CA  . MET C 2 66  ? 116.571 155.345 70.489  1.00 97.94  ? 66  MET E CA  1 
ATOM 3266 C C   . MET C 2 66  ? 117.656 154.789 69.575  1.00 97.94  ? 66  MET E C   1 
ATOM 3267 O O   . MET C 2 66  ? 118.548 154.060 70.023  1.00 97.94  ? 66  MET E O   1 
ATOM 3268 C CB  . MET C 2 66  ? 115.275 154.556 70.316  1.00 97.94  ? 66  MET E CB  1 
ATOM 3269 C CG  . MET C 2 66  ? 114.415 154.500 71.560  1.00 97.94  ? 66  MET E CG  1 
ATOM 3270 S SD  . MET C 2 66  ? 113.362 153.042 71.594  1.00 97.94  ? 66  MET E SD  1 
ATOM 3271 C CE  . MET C 2 66  ? 111.855 153.745 72.244  1.00 97.94  ? 66  MET E CE  1 
ATOM 3272 N N   . LEU C 2 67  ? 117.595 155.123 68.284  1.00 99.24  ? 67  LEU E N   1 
ATOM 3273 C CA  . LEU C 2 67  ? 118.565 154.575 67.341  1.00 99.24  ? 67  LEU E CA  1 
ATOM 3274 C C   . LEU C 2 67  ? 119.981 155.032 67.660  1.00 99.24  ? 67  LEU E C   1 
ATOM 3275 O O   . LEU C 2 67  ? 120.948 154.377 67.257  1.00 99.24  ? 67  LEU E O   1 
ATOM 3276 C CB  . LEU C 2 67  ? 118.191 154.969 65.912  1.00 99.24  ? 67  LEU E CB  1 
ATOM 3277 C CG  . LEU C 2 67  ? 116.932 154.309 65.343  1.00 99.24  ? 67  LEU E CG  1 
ATOM 3278 C CD1 . LEU C 2 67  ? 116.575 154.906 63.994  1.00 99.24  ? 67  LEU E CD1 1 
ATOM 3279 C CD2 . LEU C 2 67  ? 117.117 152.807 65.225  1.00 99.24  ? 67  LEU E CD2 1 
ATOM 3280 N N   . LYS C 2 68  ? 120.127 156.143 68.372  1.00 110.00 ? 68  LYS E N   1 
ATOM 3281 C CA  . LYS C 2 68  ? 121.447 156.636 68.745  1.00 110.00 ? 68  LYS E CA  1 
ATOM 3282 C C   . LYS C 2 68  ? 121.947 155.932 70.002  1.00 110.00 ? 68  LYS E C   1 
ATOM 3283 O O   . LYS C 2 68  ? 122.374 154.779 69.952  1.00 110.00 ? 68  LYS E O   1 
ATOM 3284 C CB  . LYS C 2 68  ? 121.415 158.150 68.966  1.00 110.00 ? 68  LYS E CB  1 
ATOM 3285 C CG  . LYS C 2 68  ? 121.218 158.956 67.690  1.00 110.00 ? 68  LYS E CG  1 
ATOM 3286 C CD  . LYS C 2 68  ? 121.180 160.457 67.959  1.00 110.00 ? 68  LYS E CD  1 
ATOM 3287 C CE  . LYS C 2 68  ? 119.963 160.864 68.778  1.00 110.00 ? 68  LYS E CE  1 
ATOM 3288 N NZ  . LYS C 2 68  ? 119.895 162.337 68.985  1.00 110.00 ? 68  LYS E NZ  1 
# 
