data_8XUM
# 
_entry.id   8XUM 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XUM         pdb_00008xum 10.2210/pdb8xum/pdb 
WWPDB D_1300044248 ?            ?                   
EMDB  EMD-38677    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XUM 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'structure of LGR4 with RSPO2' 
_pdbx_database_related.db_id          EMD-38677 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              gengyong@simm.ac.cn 
_pdbx_contact_author.name_first         Yong 
_pdbx_contact_author.name_last          Geng 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-7144-3878 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Wang, L.' 1 0000-0001-6336-5806 
'Geng, Y.' 2 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'structure of LGR4 with RSPO2' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wang, L.' 1 0000-0001-6336-5806 
primary 'Geng, Y.' 2 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man MB52                                                          12003.422  1 ? ? ? ? 
2 polymer man 'Leucine-rich repeat-containing G-protein coupled receptor 4' 104565.656 1 ? ? ? ? 
3 polymer man R-spondin-2                                                   28355.986  1 ? ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        'G-protein coupled receptor 48' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;GSLRLSCAASGYTYSPYCMGWFRQAPGKAREGVATVDLDGSTIYADSVKGRFTISQDNAKNTLYLQMNSLKPEDTAMYYC
ASRTRAGVTCGLNWAIFSYWGQGTQVTVSS
;
;GSLRLSCAASGYTYSPYCMGWFRQAPGKAREGVATVDLDGSTIYADSVKGRFTISQDNAKNTLYLQMNSLKPEDTAMYYC
ASRTRAGVTCGLNWAIFSYWGQGTQVTVSS
;
C ? 
2 'polypeptide(L)' no no 
;MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNF
PFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWL
DDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF
PQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH
LESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNL
IHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYA
NLNTEDNSLQDHSVAQEKGTADAANVTSTLENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALFFNLLVI
LTTFASCTSLPSSKLFIGLISVSNLFMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLAT
VERSLSAKDIMKNGKSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLPFPTGETPSLGFTVTLVLLNSLAFLL
MAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAISISPEIMKSVTLIFFPLPACLNPVL
YVFFNPKFKEDWKLLKRRVTKKSGSVSVSISSQGGCLEQDFYYDCGMYSHLQGNLTVCDCCESFLLTKPVSCKHLIKSHS
CPALAVASCQRPEGYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFPLVRYAYNLPRVKD
;
;MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNF
PFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWL
DDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF
PQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH
LESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNL
IHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYA
NLNTEDNSLQDHSVAQEKGTADAANVTSTLENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALFFNLLVI
LTTFASCTSLPSSKLFIGLISVSNLFMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLAT
VERSLSAKDIMKNGKSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLPFPTGETPSLGFTVTLVLLNSLAFLL
MAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAISISPEIMKSVTLIFFPLPACLNPVL
YVFFNPKFKEDWKLLKRRVTKKSGSVSVSISSQGGCLEQDFYYDCGMYSHLQGNLTVCDCCESFLLTKPVSCKHLIKSHS
CPALAVASCQRPEGYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFPLVRYAYNLPRVKD
;
A ? 
3 'polypeptide(L)' no no 
;MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPS
GYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLDETMECVEGCEVGHWSEWGTCSRNN
RTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDR
ANQ
;
;MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPS
GYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLDETMECVEGCEVGHWSEWGTCSRNN
RTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDR
ANQ
;
B ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   SER n 
1 3   LEU n 
1 4   ARG n 
1 5   LEU n 
1 6   SER n 
1 7   CYS n 
1 8   ALA n 
1 9   ALA n 
1 10  SER n 
1 11  GLY n 
1 12  TYR n 
1 13  THR n 
1 14  TYR n 
1 15  SER n 
1 16  PRO n 
1 17  TYR n 
1 18  CYS n 
1 19  MET n 
1 20  GLY n 
1 21  TRP n 
1 22  PHE n 
1 23  ARG n 
1 24  GLN n 
1 25  ALA n 
1 26  PRO n 
1 27  GLY n 
1 28  LYS n 
1 29  ALA n 
1 30  ARG n 
1 31  GLU n 
1 32  GLY n 
1 33  VAL n 
1 34  ALA n 
1 35  THR n 
1 36  VAL n 
1 37  ASP n 
1 38  LEU n 
1 39  ASP n 
1 40  GLY n 
1 41  SER n 
1 42  THR n 
1 43  ILE n 
1 44  TYR n 
1 45  ALA n 
1 46  ASP n 
1 47  SER n 
1 48  VAL n 
1 49  LYS n 
1 50  GLY n 
1 51  ARG n 
1 52  PHE n 
1 53  THR n 
1 54  ILE n 
1 55  SER n 
1 56  GLN n 
1 57  ASP n 
1 58  ASN n 
1 59  ALA n 
1 60  LYS n 
1 61  ASN n 
1 62  THR n 
1 63  LEU n 
1 64  TYR n 
1 65  LEU n 
1 66  GLN n 
1 67  MET n 
1 68  ASN n 
1 69  SER n 
1 70  LEU n 
1 71  LYS n 
1 72  PRO n 
1 73  GLU n 
1 74  ASP n 
1 75  THR n 
1 76  ALA n 
1 77  MET n 
1 78  TYR n 
1 79  TYR n 
1 80  CYS n 
1 81  ALA n 
1 82  SER n 
1 83  ARG n 
1 84  THR n 
1 85  ARG n 
1 86  ALA n 
1 87  GLY n 
1 88  VAL n 
1 89  THR n 
1 90  CYS n 
1 91  GLY n 
1 92  LEU n 
1 93  ASN n 
1 94  TRP n 
1 95  ALA n 
1 96  ILE n 
1 97  PHE n 
1 98  SER n 
1 99  TYR n 
1 100 TRP n 
1 101 GLY n 
1 102 GLN n 
1 103 GLY n 
1 104 THR n 
1 105 GLN n 
1 106 VAL n 
1 107 THR n 
1 108 VAL n 
1 109 SER n 
1 110 SER n 
2 1   MET n 
2 2   PRO n 
2 3   GLY n 
2 4   PRO n 
2 5   LEU n 
2 6   GLY n 
2 7   LEU n 
2 8   LEU n 
2 9   CYS n 
2 10  PHE n 
2 11  LEU n 
2 12  ALA n 
2 13  LEU n 
2 14  GLY n 
2 15  LEU n 
2 16  LEU n 
2 17  GLY n 
2 18  SER n 
2 19  ALA n 
2 20  GLY n 
2 21  PRO n 
2 22  SER n 
2 23  GLY n 
2 24  ALA n 
2 25  ALA n 
2 26  PRO n 
2 27  PRO n 
2 28  LEU n 
2 29  CYS n 
2 30  ALA n 
2 31  ALA n 
2 32  PRO n 
2 33  CYS n 
2 34  SER n 
2 35  CYS n 
2 36  ASP n 
2 37  GLY n 
2 38  ASP n 
2 39  ARG n 
2 40  ARG n 
2 41  VAL n 
2 42  ASP n 
2 43  CYS n 
2 44  SER n 
2 45  GLY n 
2 46  LYS n 
2 47  GLY n 
2 48  LEU n 
2 49  THR n 
2 50  ALA n 
2 51  VAL n 
2 52  PRO n 
2 53  GLU n 
2 54  GLY n 
2 55  LEU n 
2 56  SER n 
2 57  ALA n 
2 58  PHE n 
2 59  THR n 
2 60  GLN n 
2 61  ALA n 
2 62  LEU n 
2 63  ASP n 
2 64  ILE n 
2 65  SER n 
2 66  MET n 
2 67  ASN n 
2 68  ASN n 
2 69  ILE n 
2 70  THR n 
2 71  GLN n 
2 72  LEU n 
2 73  PRO n 
2 74  GLU n 
2 75  ASP n 
2 76  ALA n 
2 77  PHE n 
2 78  LYS n 
2 79  ASN n 
2 80  PHE n 
2 81  PRO n 
2 82  PHE n 
2 83  LEU n 
2 84  GLU n 
2 85  GLU n 
2 86  LEU n 
2 87  GLN n 
2 88  LEU n 
2 89  ALA n 
2 90  GLY n 
2 91  ASN n 
2 92  ASP n 
2 93  LEU n 
2 94  SER n 
2 95  PHE n 
2 96  ILE n 
2 97  HIS n 
2 98  PRO n 
2 99  LYS n 
2 100 ALA n 
2 101 LEU n 
2 102 SER n 
2 103 GLY n 
2 104 LEU n 
2 105 LYS n 
2 106 GLU n 
2 107 LEU n 
2 108 LYS n 
2 109 VAL n 
2 110 LEU n 
2 111 THR n 
2 112 LEU n 
2 113 GLN n 
2 114 ASN n 
2 115 ASN n 
2 116 GLN n 
2 117 LEU n 
2 118 LYS n 
2 119 THR n 
2 120 VAL n 
2 121 PRO n 
2 122 SER n 
2 123 GLU n 
2 124 ALA n 
2 125 ILE n 
2 126 ARG n 
2 127 GLY n 
2 128 LEU n 
2 129 SER n 
2 130 ALA n 
2 131 LEU n 
2 132 GLN n 
2 133 SER n 
2 134 LEU n 
2 135 ARG n 
2 136 LEU n 
2 137 ASP n 
2 138 ALA n 
2 139 ASN n 
2 140 HIS n 
2 141 ILE n 
2 142 THR n 
2 143 SER n 
2 144 VAL n 
2 145 PRO n 
2 146 GLU n 
2 147 ASP n 
2 148 SER n 
2 149 PHE n 
2 150 GLU n 
2 151 GLY n 
2 152 LEU n 
2 153 VAL n 
2 154 GLN n 
2 155 LEU n 
2 156 ARG n 
2 157 HIS n 
2 158 LEU n 
2 159 TRP n 
2 160 LEU n 
2 161 ASP n 
2 162 ASP n 
2 163 ASN n 
2 164 SER n 
2 165 LEU n 
2 166 THR n 
2 167 GLU n 
2 168 VAL n 
2 169 PRO n 
2 170 VAL n 
2 171 HIS n 
2 172 PRO n 
2 173 LEU n 
2 174 SER n 
2 175 ASN n 
2 176 LEU n 
2 177 PRO n 
2 178 THR n 
2 179 LEU n 
2 180 GLN n 
2 181 ALA n 
2 182 LEU n 
2 183 THR n 
2 184 LEU n 
2 185 ALA n 
2 186 LEU n 
2 187 ASN n 
2 188 LYS n 
2 189 ILE n 
2 190 SER n 
2 191 SER n 
2 192 ILE n 
2 193 PRO n 
2 194 ASP n 
2 195 PHE n 
2 196 ALA n 
2 197 PHE n 
2 198 THR n 
2 199 ASN n 
2 200 LEU n 
2 201 SER n 
2 202 SER n 
2 203 LEU n 
2 204 VAL n 
2 205 VAL n 
2 206 LEU n 
2 207 HIS n 
2 208 LEU n 
2 209 HIS n 
2 210 ASN n 
2 211 ASN n 
2 212 LYS n 
2 213 ILE n 
2 214 ARG n 
2 215 SER n 
2 216 LEU n 
2 217 SER n 
2 218 GLN n 
2 219 HIS n 
2 220 CYS n 
2 221 PHE n 
2 222 ASP n 
2 223 GLY n 
2 224 LEU n 
2 225 ASP n 
2 226 ASN n 
2 227 LEU n 
2 228 GLU n 
2 229 THR n 
2 230 LEU n 
2 231 ASP n 
2 232 LEU n 
2 233 ASN n 
2 234 TYR n 
2 235 ASN n 
2 236 ASN n 
2 237 LEU n 
2 238 GLY n 
2 239 GLU n 
2 240 PHE n 
2 241 PRO n 
2 242 GLN n 
2 243 ALA n 
2 244 ILE n 
2 245 LYS n 
2 246 ALA n 
2 247 LEU n 
2 248 PRO n 
2 249 SER n 
2 250 LEU n 
2 251 LYS n 
2 252 GLU n 
2 253 LEU n 
2 254 GLY n 
2 255 PHE n 
2 256 HIS n 
2 257 SER n 
2 258 ASN n 
2 259 SER n 
2 260 ILE n 
2 261 SER n 
2 262 VAL n 
2 263 ILE n 
2 264 PRO n 
2 265 ASP n 
2 266 GLY n 
2 267 ALA n 
2 268 PHE n 
2 269 ASP n 
2 270 GLY n 
2 271 ASN n 
2 272 PRO n 
2 273 LEU n 
2 274 LEU n 
2 275 ARG n 
2 276 THR n 
2 277 ILE n 
2 278 HIS n 
2 279 LEU n 
2 280 TYR n 
2 281 ASP n 
2 282 ASN n 
2 283 PRO n 
2 284 LEU n 
2 285 SER n 
2 286 PHE n 
2 287 VAL n 
2 288 GLY n 
2 289 ASN n 
2 290 SER n 
2 291 ALA n 
2 292 PHE n 
2 293 HIS n 
2 294 ASN n 
2 295 LEU n 
2 296 SER n 
2 297 ASP n 
2 298 LEU n 
2 299 HIS n 
2 300 SER n 
2 301 LEU n 
2 302 VAL n 
2 303 ILE n 
2 304 ARG n 
2 305 GLY n 
2 306 ALA n 
2 307 SER n 
2 308 MET n 
2 309 VAL n 
2 310 GLN n 
2 311 GLN n 
2 312 PHE n 
2 313 PRO n 
2 314 ASN n 
2 315 LEU n 
2 316 THR n 
2 317 GLY n 
2 318 THR n 
2 319 VAL n 
2 320 HIS n 
2 321 LEU n 
2 322 GLU n 
2 323 SER n 
2 324 LEU n 
2 325 THR n 
2 326 LEU n 
2 327 THR n 
2 328 GLY n 
2 329 THR n 
2 330 LYS n 
2 331 ILE n 
2 332 SER n 
2 333 SER n 
2 334 ILE n 
2 335 PRO n 
2 336 ASN n 
2 337 ASN n 
2 338 LEU n 
2 339 CYS n 
2 340 GLN n 
2 341 GLU n 
2 342 GLN n 
2 343 LYS n 
2 344 MET n 
2 345 LEU n 
2 346 ARG n 
2 347 THR n 
2 348 LEU n 
2 349 ASP n 
2 350 LEU n 
2 351 SER n 
2 352 TYR n 
2 353 ASN n 
2 354 ASN n 
2 355 ILE n 
2 356 ARG n 
2 357 ASP n 
2 358 LEU n 
2 359 PRO n 
2 360 SER n 
2 361 PHE n 
2 362 ASN n 
2 363 GLY n 
2 364 CYS n 
2 365 HIS n 
2 366 ALA n 
2 367 LEU n 
2 368 GLU n 
2 369 GLU n 
2 370 ILE n 
2 371 SER n 
2 372 LEU n 
2 373 GLN n 
2 374 ARG n 
2 375 ASN n 
2 376 GLN n 
2 377 ILE n 
2 378 TYR n 
2 379 GLN n 
2 380 ILE n 
2 381 LYS n 
2 382 GLU n 
2 383 GLY n 
2 384 THR n 
2 385 PHE n 
2 386 GLN n 
2 387 GLY n 
2 388 LEU n 
2 389 ILE n 
2 390 SER n 
2 391 LEU n 
2 392 ARG n 
2 393 ILE n 
2 394 LEU n 
2 395 ASP n 
2 396 LEU n 
2 397 SER n 
2 398 ARG n 
2 399 ASN n 
2 400 LEU n 
2 401 ILE n 
2 402 HIS n 
2 403 GLU n 
2 404 ILE n 
2 405 HIS n 
2 406 SER n 
2 407 ARG n 
2 408 ALA n 
2 409 PHE n 
2 410 ALA n 
2 411 THR n 
2 412 LEU n 
2 413 GLY n 
2 414 PRO n 
2 415 ILE n 
2 416 THR n 
2 417 ASN n 
2 418 LEU n 
2 419 ASP n 
2 420 VAL n 
2 421 SER n 
2 422 PHE n 
2 423 ASN n 
2 424 GLU n 
2 425 LEU n 
2 426 THR n 
2 427 SER n 
2 428 PHE n 
2 429 PRO n 
2 430 THR n 
2 431 GLU n 
2 432 GLY n 
2 433 LEU n 
2 434 ASN n 
2 435 GLY n 
2 436 LEU n 
2 437 ASN n 
2 438 GLN n 
2 439 LEU n 
2 440 LYS n 
2 441 LEU n 
2 442 VAL n 
2 443 GLY n 
2 444 ASN n 
2 445 PHE n 
2 446 LYS n 
2 447 LEU n 
2 448 LYS n 
2 449 GLU n 
2 450 ALA n 
2 451 LEU n 
2 452 ALA n 
2 453 ALA n 
2 454 LYS n 
2 455 ASP n 
2 456 PHE n 
2 457 VAL n 
2 458 ASN n 
2 459 LEU n 
2 460 ARG n 
2 461 SER n 
2 462 LEU n 
2 463 SER n 
2 464 VAL n 
2 465 PRO n 
2 466 TYR n 
2 467 ALA n 
2 468 TYR n 
2 469 GLN n 
2 470 CYS n 
2 471 CYS n 
2 472 ALA n 
2 473 PHE n 
2 474 TRP n 
2 475 GLY n 
2 476 CYS n 
2 477 ASP n 
2 478 SER n 
2 479 TYR n 
2 480 ALA n 
2 481 ASN n 
2 482 LEU n 
2 483 ASN n 
2 484 THR n 
2 485 GLU n 
2 486 ASP n 
2 487 ASN n 
2 488 SER n 
2 489 LEU n 
2 490 GLN n 
2 491 ASP n 
2 492 HIS n 
2 493 SER n 
2 494 VAL n 
2 495 ALA n 
2 496 GLN n 
2 497 GLU n 
2 498 LYS n 
2 499 GLY n 
2 500 THR n 
2 501 ALA n 
2 502 ASP n 
2 503 ALA n 
2 504 ALA n 
2 505 ASN n 
2 506 VAL n 
2 507 THR n 
2 508 SER n 
2 509 THR n 
2 510 LEU n 
2 511 GLU n 
2 512 ASN n 
2 513 GLU n 
2 514 GLU n 
2 515 HIS n 
2 516 SER n 
2 517 GLN n 
2 518 ILE n 
2 519 ILE n 
2 520 ILE n 
2 521 HIS n 
2 522 CYS n 
2 523 THR n 
2 524 PRO n 
2 525 SER n 
2 526 THR n 
2 527 GLY n 
2 528 ALA n 
2 529 PHE n 
2 530 LYS n 
2 531 PRO n 
2 532 CYS n 
2 533 GLU n 
2 534 TYR n 
2 535 LEU n 
2 536 LEU n 
2 537 GLY n 
2 538 SER n 
2 539 TRP n 
2 540 MET n 
2 541 ILE n 
2 542 ARG n 
2 543 LEU n 
2 544 THR n 
2 545 VAL n 
2 546 TRP n 
2 547 PHE n 
2 548 ILE n 
2 549 PHE n 
2 550 LEU n 
2 551 VAL n 
2 552 ALA n 
2 553 LEU n 
2 554 PHE n 
2 555 PHE n 
2 556 ASN n 
2 557 LEU n 
2 558 LEU n 
2 559 VAL n 
2 560 ILE n 
2 561 LEU n 
2 562 THR n 
2 563 THR n 
2 564 PHE n 
2 565 ALA n 
2 566 SER n 
2 567 CYS n 
2 568 THR n 
2 569 SER n 
2 570 LEU n 
2 571 PRO n 
2 572 SER n 
2 573 SER n 
2 574 LYS n 
2 575 LEU n 
2 576 PHE n 
2 577 ILE n 
2 578 GLY n 
2 579 LEU n 
2 580 ILE n 
2 581 SER n 
2 582 VAL n 
2 583 SER n 
2 584 ASN n 
2 585 LEU n 
2 586 PHE n 
2 587 MET n 
2 588 GLY n 
2 589 ILE n 
2 590 TYR n 
2 591 THR n 
2 592 GLY n 
2 593 ILE n 
2 594 LEU n 
2 595 THR n 
2 596 PHE n 
2 597 LEU n 
2 598 ASP n 
2 599 ALA n 
2 600 VAL n 
2 601 SER n 
2 602 TRP n 
2 603 GLY n 
2 604 ARG n 
2 605 PHE n 
2 606 ALA n 
2 607 GLU n 
2 608 PHE n 
2 609 GLY n 
2 610 ILE n 
2 611 TRP n 
2 612 TRP n 
2 613 GLU n 
2 614 THR n 
2 615 GLY n 
2 616 SER n 
2 617 GLY n 
2 618 CYS n 
2 619 LYS n 
2 620 VAL n 
2 621 ALA n 
2 622 GLY n 
2 623 PHE n 
2 624 LEU n 
2 625 ALA n 
2 626 VAL n 
2 627 PHE n 
2 628 SER n 
2 629 SER n 
2 630 GLU n 
2 631 SER n 
2 632 ALA n 
2 633 ILE n 
2 634 PHE n 
2 635 LEU n 
2 636 LEU n 
2 637 MET n 
2 638 LEU n 
2 639 ALA n 
2 640 THR n 
2 641 VAL n 
2 642 GLU n 
2 643 ARG n 
2 644 SER n 
2 645 LEU n 
2 646 SER n 
2 647 ALA n 
2 648 LYS n 
2 649 ASP n 
2 650 ILE n 
2 651 MET n 
2 652 LYS n 
2 653 ASN n 
2 654 GLY n 
2 655 LYS n 
2 656 SER n 
2 657 ASN n 
2 658 HIS n 
2 659 LEU n 
2 660 LYS n 
2 661 GLN n 
2 662 PHE n 
2 663 ARG n 
2 664 VAL n 
2 665 ALA n 
2 666 ALA n 
2 667 LEU n 
2 668 LEU n 
2 669 ALA n 
2 670 PHE n 
2 671 LEU n 
2 672 GLY n 
2 673 ALA n 
2 674 THR n 
2 675 VAL n 
2 676 ALA n 
2 677 GLY n 
2 678 CYS n 
2 679 PHE n 
2 680 PRO n 
2 681 LEU n 
2 682 PHE n 
2 683 HIS n 
2 684 ARG n 
2 685 GLY n 
2 686 GLU n 
2 687 TYR n 
2 688 SER n 
2 689 ALA n 
2 690 SER n 
2 691 PRO n 
2 692 LEU n 
2 693 CYS n 
2 694 LEU n 
2 695 PRO n 
2 696 PHE n 
2 697 PRO n 
2 698 THR n 
2 699 GLY n 
2 700 GLU n 
2 701 THR n 
2 702 PRO n 
2 703 SER n 
2 704 LEU n 
2 705 GLY n 
2 706 PHE n 
2 707 THR n 
2 708 VAL n 
2 709 THR n 
2 710 LEU n 
2 711 VAL n 
2 712 LEU n 
2 713 LEU n 
2 714 ASN n 
2 715 SER n 
2 716 LEU n 
2 717 ALA n 
2 718 PHE n 
2 719 LEU n 
2 720 LEU n 
2 721 MET n 
2 722 ALA n 
2 723 VAL n 
2 724 ILE n 
2 725 TYR n 
2 726 THR n 
2 727 LYS n 
2 728 LEU n 
2 729 TYR n 
2 730 CYS n 
2 731 ASN n 
2 732 LEU n 
2 733 GLU n 
2 734 LYS n 
2 735 GLU n 
2 736 ASP n 
2 737 LEU n 
2 738 SER n 
2 739 GLU n 
2 740 ASN n 
2 741 SER n 
2 742 GLN n 
2 743 SER n 
2 744 SER n 
2 745 MET n 
2 746 ILE n 
2 747 LYS n 
2 748 HIS n 
2 749 VAL n 
2 750 ALA n 
2 751 TRP n 
2 752 LEU n 
2 753 ILE n 
2 754 PHE n 
2 755 THR n 
2 756 ASN n 
2 757 CYS n 
2 758 ILE n 
2 759 PHE n 
2 760 PHE n 
2 761 CYS n 
2 762 PRO n 
2 763 VAL n 
2 764 ALA n 
2 765 PHE n 
2 766 PHE n 
2 767 SER n 
2 768 PHE n 
2 769 ALA n 
2 770 PRO n 
2 771 LEU n 
2 772 ILE n 
2 773 THR n 
2 774 ALA n 
2 775 ILE n 
2 776 SER n 
2 777 ILE n 
2 778 SER n 
2 779 PRO n 
2 780 GLU n 
2 781 ILE n 
2 782 MET n 
2 783 LYS n 
2 784 SER n 
2 785 VAL n 
2 786 THR n 
2 787 LEU n 
2 788 ILE n 
2 789 PHE n 
2 790 PHE n 
2 791 PRO n 
2 792 LEU n 
2 793 PRO n 
2 794 ALA n 
2 795 CYS n 
2 796 LEU n 
2 797 ASN n 
2 798 PRO n 
2 799 VAL n 
2 800 LEU n 
2 801 TYR n 
2 802 VAL n 
2 803 PHE n 
2 804 PHE n 
2 805 ASN n 
2 806 PRO n 
2 807 LYS n 
2 808 PHE n 
2 809 LYS n 
2 810 GLU n 
2 811 ASP n 
2 812 TRP n 
2 813 LYS n 
2 814 LEU n 
2 815 LEU n 
2 816 LYS n 
2 817 ARG n 
2 818 ARG n 
2 819 VAL n 
2 820 THR n 
2 821 LYS n 
2 822 LYS n 
2 823 SER n 
2 824 GLY n 
2 825 SER n 
2 826 VAL n 
2 827 SER n 
2 828 VAL n 
2 829 SER n 
2 830 ILE n 
2 831 SER n 
2 832 SER n 
2 833 GLN n 
2 834 GLY n 
2 835 GLY n 
2 836 CYS n 
2 837 LEU n 
2 838 GLU n 
2 839 GLN n 
2 840 ASP n 
2 841 PHE n 
2 842 TYR n 
2 843 TYR n 
2 844 ASP n 
2 845 CYS n 
2 846 GLY n 
2 847 MET n 
2 848 TYR n 
2 849 SER n 
2 850 HIS n 
2 851 LEU n 
2 852 GLN n 
2 853 GLY n 
2 854 ASN n 
2 855 LEU n 
2 856 THR n 
2 857 VAL n 
2 858 CYS n 
2 859 ASP n 
2 860 CYS n 
2 861 CYS n 
2 862 GLU n 
2 863 SER n 
2 864 PHE n 
2 865 LEU n 
2 866 LEU n 
2 867 THR n 
2 868 LYS n 
2 869 PRO n 
2 870 VAL n 
2 871 SER n 
2 872 CYS n 
2 873 LYS n 
2 874 HIS n 
2 875 LEU n 
2 876 ILE n 
2 877 LYS n 
2 878 SER n 
2 879 HIS n 
2 880 SER n 
2 881 CYS n 
2 882 PRO n 
2 883 ALA n 
2 884 LEU n 
2 885 ALA n 
2 886 VAL n 
2 887 ALA n 
2 888 SER n 
2 889 CYS n 
2 890 GLN n 
2 891 ARG n 
2 892 PRO n 
2 893 GLU n 
2 894 GLY n 
2 895 TYR n 
2 896 TRP n 
2 897 SER n 
2 898 ASP n 
2 899 CYS n 
2 900 GLY n 
2 901 THR n 
2 902 GLN n 
2 903 SER n 
2 904 ALA n 
2 905 HIS n 
2 906 SER n 
2 907 ASP n 
2 908 TYR n 
2 909 ALA n 
2 910 ASP n 
2 911 GLU n 
2 912 GLU n 
2 913 ASP n 
2 914 SER n 
2 915 PHE n 
2 916 VAL n 
2 917 SER n 
2 918 ASP n 
2 919 SER n 
2 920 SER n 
2 921 ASP n 
2 922 GLN n 
2 923 VAL n 
2 924 GLN n 
2 925 ALA n 
2 926 CYS n 
2 927 GLY n 
2 928 ARG n 
2 929 ALA n 
2 930 CYS n 
2 931 PHE n 
2 932 TYR n 
2 933 GLN n 
2 934 SER n 
2 935 ARG n 
2 936 GLY n 
2 937 PHE n 
2 938 PRO n 
2 939 LEU n 
2 940 VAL n 
2 941 ARG n 
2 942 TYR n 
2 943 ALA n 
2 944 TYR n 
2 945 ASN n 
2 946 LEU n 
2 947 PRO n 
2 948 ARG n 
2 949 VAL n 
2 950 LYS n 
2 951 ASP n 
3 1   MET n 
3 2   GLN n 
3 3   PHE n 
3 4   ARG n 
3 5   LEU n 
3 6   PHE n 
3 7   SER n 
3 8   PHE n 
3 9   ALA n 
3 10  LEU n 
3 11  ILE n 
3 12  ILE n 
3 13  LEU n 
3 14  ASN n 
3 15  CYS n 
3 16  MET n 
3 17  ASP n 
3 18  TYR n 
3 19  SER n 
3 20  HIS n 
3 21  CYS n 
3 22  GLN n 
3 23  GLY n 
3 24  ASN n 
3 25  ARG n 
3 26  TRP n 
3 27  ARG n 
3 28  ARG n 
3 29  SER n 
3 30  LYS n 
3 31  ARG n 
3 32  ALA n 
3 33  SER n 
3 34  TYR n 
3 35  VAL n 
3 36  SER n 
3 37  ASN n 
3 38  PRO n 
3 39  ILE n 
3 40  CYS n 
3 41  LYS n 
3 42  GLY n 
3 43  CYS n 
3 44  LEU n 
3 45  SER n 
3 46  CYS n 
3 47  SER n 
3 48  LYS n 
3 49  ASP n 
3 50  ASN n 
3 51  GLY n 
3 52  CYS n 
3 53  SER n 
3 54  ARG n 
3 55  CYS n 
3 56  GLN n 
3 57  GLN n 
3 58  LYS n 
3 59  LEU n 
3 60  PHE n 
3 61  PHE n 
3 62  PHE n 
3 63  LEU n 
3 64  ARG n 
3 65  ARG n 
3 66  GLU n 
3 67  GLY n 
3 68  MET n 
3 69  ARG n 
3 70  GLN n 
3 71  TYR n 
3 72  GLY n 
3 73  GLU n 
3 74  CYS n 
3 75  LEU n 
3 76  HIS n 
3 77  SER n 
3 78  CYS n 
3 79  PRO n 
3 80  SER n 
3 81  GLY n 
3 82  TYR n 
3 83  TYR n 
3 84  GLY n 
3 85  HIS n 
3 86  ARG n 
3 87  ALA n 
3 88  PRO n 
3 89  ASP n 
3 90  MET n 
3 91  ASN n 
3 92  ARG n 
3 93  CYS n 
3 94  ALA n 
3 95  ARG n 
3 96  CYS n 
3 97  ARG n 
3 98  ILE n 
3 99  GLU n 
3 100 ASN n 
3 101 CYS n 
3 102 ASP n 
3 103 SER n 
3 104 CYS n 
3 105 PHE n 
3 106 SER n 
3 107 LYS n 
3 108 ASP n 
3 109 PHE n 
3 110 CYS n 
3 111 THR n 
3 112 LYS n 
3 113 CYS n 
3 114 LYS n 
3 115 VAL n 
3 116 GLY n 
3 117 PHE n 
3 118 TYR n 
3 119 LEU n 
3 120 HIS n 
3 121 ARG n 
3 122 GLY n 
3 123 ARG n 
3 124 CYS n 
3 125 PHE n 
3 126 ASP n 
3 127 GLU n 
3 128 CYS n 
3 129 PRO n 
3 130 ASP n 
3 131 GLY n 
3 132 PHE n 
3 133 ALA n 
3 134 PRO n 
3 135 LEU n 
3 136 ASP n 
3 137 GLU n 
3 138 THR n 
3 139 MET n 
3 140 GLU n 
3 141 CYS n 
3 142 VAL n 
3 143 GLU n 
3 144 GLY n 
3 145 CYS n 
3 146 GLU n 
3 147 VAL n 
3 148 GLY n 
3 149 HIS n 
3 150 TRP n 
3 151 SER n 
3 152 GLU n 
3 153 TRP n 
3 154 GLY n 
3 155 THR n 
3 156 CYS n 
3 157 SER n 
3 158 ARG n 
3 159 ASN n 
3 160 ASN n 
3 161 ARG n 
3 162 THR n 
3 163 CYS n 
3 164 GLY n 
3 165 PHE n 
3 166 LYS n 
3 167 TRP n 
3 168 GLY n 
3 169 LEU n 
3 170 GLU n 
3 171 THR n 
3 172 ARG n 
3 173 THR n 
3 174 ARG n 
3 175 GLN n 
3 176 ILE n 
3 177 VAL n 
3 178 LYS n 
3 179 LYS n 
3 180 PRO n 
3 181 VAL n 
3 182 LYS n 
3 183 ASP n 
3 184 THR n 
3 185 ILE n 
3 186 LEU n 
3 187 CYS n 
3 188 PRO n 
3 189 THR n 
3 190 ILE n 
3 191 ALA n 
3 192 GLU n 
3 193 SER n 
3 194 ARG n 
3 195 ARG n 
3 196 CYS n 
3 197 LYS n 
3 198 MET n 
3 199 THR n 
3 200 MET n 
3 201 ARG n 
3 202 HIS n 
3 203 CYS n 
3 204 PRO n 
3 205 GLY n 
3 206 GLY n 
3 207 LYS n 
3 208 ARG n 
3 209 THR n 
3 210 PRO n 
3 211 LYS n 
3 212 ALA n 
3 213 LYS n 
3 214 GLU n 
3 215 LYS n 
3 216 ARG n 
3 217 ASN n 
3 218 LYS n 
3 219 LYS n 
3 220 LYS n 
3 221 LYS n 
3 222 ARG n 
3 223 LYS n 
3 224 LEU n 
3 225 ILE n 
3 226 GLU n 
3 227 ARG n 
3 228 ALA n 
3 229 GLN n 
3 230 GLU n 
3 231 GLN n 
3 232 HIS n 
3 233 SER n 
3 234 VAL n 
3 235 PHE n 
3 236 LEU n 
3 237 ALA n 
3 238 THR n 
3 239 ASP n 
3 240 ARG n 
3 241 ALA n 
3 242 ASN n 
3 243 GLN n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 110 ?     ? ?             ? ? ? ? ? ? 'Camelus bactrianus' 9837 ? ? ? ? ? ? ? ? 
'Escherichia coli' 562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 951 human ? 'LGR4, GPR48' ? ? ? ? ? ? 'Homo sapiens'       9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 243 human ? RSPO2         ? ? ? ? ? ? 'Homo sapiens'       9606 ? ? ? ? ? ? ? ? 'Homo sapiens' 
9606 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   441 441 GLY GLY C . n 
A 1 2   SER 2   442 442 SER SER C . n 
A 1 3   LEU 3   443 443 LEU LEU C . n 
A 1 4   ARG 4   444 444 ARG ARG C . n 
A 1 5   LEU 5   445 445 LEU LEU C . n 
A 1 6   SER 6   446 446 SER SER C . n 
A 1 7   CYS 7   447 447 CYS CYS C . n 
A 1 8   ALA 8   448 448 ALA ALA C . n 
A 1 9   ALA 9   449 449 ALA ALA C . n 
A 1 10  SER 10  450 450 SER SER C . n 
A 1 11  GLY 11  451 451 GLY GLY C . n 
A 1 12  TYR 12  452 452 TYR TYR C . n 
A 1 13  THR 13  453 453 THR THR C . n 
A 1 14  TYR 14  454 454 TYR TYR C . n 
A 1 15  SER 15  455 455 SER SER C . n 
A 1 16  PRO 16  456 456 PRO PRO C . n 
A 1 17  TYR 17  457 457 TYR TYR C . n 
A 1 18  CYS 18  458 458 CYS CYS C . n 
A 1 19  MET 19  459 459 MET MET C . n 
A 1 20  GLY 20  460 460 GLY GLY C . n 
A 1 21  TRP 21  461 461 TRP TRP C . n 
A 1 22  PHE 22  462 462 PHE PHE C . n 
A 1 23  ARG 23  463 463 ARG ARG C . n 
A 1 24  GLN 24  464 464 GLN GLN C . n 
A 1 25  ALA 25  465 465 ALA ALA C . n 
A 1 26  PRO 26  466 466 PRO PRO C . n 
A 1 27  GLY 27  467 467 GLY GLY C . n 
A 1 28  LYS 28  468 468 LYS LYS C . n 
A 1 29  ALA 29  469 469 ALA ALA C . n 
A 1 30  ARG 30  470 470 ARG ARG C . n 
A 1 31  GLU 31  471 471 GLU GLU C . n 
A 1 32  GLY 32  472 472 GLY GLY C . n 
A 1 33  VAL 33  473 473 VAL VAL C . n 
A 1 34  ALA 34  474 474 ALA ALA C . n 
A 1 35  THR 35  475 475 THR THR C . n 
A 1 36  VAL 36  476 476 VAL VAL C . n 
A 1 37  ASP 37  477 477 ASP ASP C . n 
A 1 38  LEU 38  478 478 LEU LEU C . n 
A 1 39  ASP 39  479 479 ASP ASP C . n 
A 1 40  GLY 40  480 480 GLY GLY C . n 
A 1 41  SER 41  481 481 SER SER C . n 
A 1 42  THR 42  482 482 THR THR C . n 
A 1 43  ILE 43  483 483 ILE ILE C . n 
A 1 44  TYR 44  484 484 TYR TYR C . n 
A 1 45  ALA 45  485 485 ALA ALA C . n 
A 1 46  ASP 46  486 486 ASP ASP C . n 
A 1 47  SER 47  487 487 SER SER C . n 
A 1 48  VAL 48  488 488 VAL VAL C . n 
A 1 49  LYS 49  489 489 LYS LYS C . n 
A 1 50  GLY 50  490 490 GLY GLY C . n 
A 1 51  ARG 51  491 491 ARG ARG C . n 
A 1 52  PHE 52  492 492 PHE PHE C . n 
A 1 53  THR 53  493 493 THR THR C . n 
A 1 54  ILE 54  494 494 ILE ILE C . n 
A 1 55  SER 55  495 495 SER SER C . n 
A 1 56  GLN 56  496 496 GLN GLN C . n 
A 1 57  ASP 57  497 497 ASP ASP C . n 
A 1 58  ASN 58  498 498 ASN ASN C . n 
A 1 59  ALA 59  499 499 ALA ALA C . n 
A 1 60  LYS 60  500 500 LYS LYS C . n 
A 1 61  ASN 61  501 501 ASN ASN C . n 
A 1 62  THR 62  502 502 THR THR C . n 
A 1 63  LEU 63  503 503 LEU LEU C . n 
A 1 64  TYR 64  504 504 TYR TYR C . n 
A 1 65  LEU 65  505 505 LEU LEU C . n 
A 1 66  GLN 66  506 506 GLN GLN C . n 
A 1 67  MET 67  507 507 MET MET C . n 
A 1 68  ASN 68  508 508 ASN ASN C . n 
A 1 69  SER 69  509 509 SER SER C . n 
A 1 70  LEU 70  510 510 LEU LEU C . n 
A 1 71  LYS 71  511 511 LYS LYS C . n 
A 1 72  PRO 72  512 512 PRO PRO C . n 
A 1 73  GLU 73  513 513 GLU GLU C . n 
A 1 74  ASP 74  514 514 ASP ASP C . n 
A 1 75  THR 75  515 515 THR THR C . n 
A 1 76  ALA 76  516 516 ALA ALA C . n 
A 1 77  MET 77  517 517 MET MET C . n 
A 1 78  TYR 78  518 518 TYR TYR C . n 
A 1 79  TYR 79  519 519 TYR TYR C . n 
A 1 80  CYS 80  520 520 CYS CYS C . n 
A 1 81  ALA 81  521 521 ALA ALA C . n 
A 1 82  SER 82  522 522 SER SER C . n 
A 1 83  ARG 83  523 523 ARG ARG C . n 
A 1 84  THR 84  524 524 THR THR C . n 
A 1 85  ARG 85  525 525 ARG ARG C . n 
A 1 86  ALA 86  526 526 ALA ALA C . n 
A 1 87  GLY 87  527 527 GLY GLY C . n 
A 1 88  VAL 88  528 528 VAL VAL C . n 
A 1 89  THR 89  529 529 THR THR C . n 
A 1 90  CYS 90  530 530 CYS CYS C . n 
A 1 91  GLY 91  531 531 GLY GLY C . n 
A 1 92  LEU 92  532 532 LEU LEU C . n 
A 1 93  ASN 93  533 533 ASN ASN C . n 
A 1 94  TRP 94  534 534 TRP TRP C . n 
A 1 95  ALA 95  535 535 ALA ALA C . n 
A 1 96  ILE 96  536 536 ILE ILE C . n 
A 1 97  PHE 97  537 537 PHE PHE C . n 
A 1 98  SER 98  538 538 SER SER C . n 
A 1 99  TYR 99  539 539 TYR TYR C . n 
A 1 100 TRP 100 540 540 TRP TRP C . n 
A 1 101 GLY 101 541 541 GLY GLY C . n 
A 1 102 GLN 102 542 542 GLN GLN C . n 
A 1 103 GLY 103 543 543 GLY GLY C . n 
A 1 104 THR 104 544 544 THR THR C . n 
A 1 105 GLN 105 545 545 GLN GLN C . n 
A 1 106 VAL 106 546 546 VAL VAL C . n 
A 1 107 THR 107 547 547 THR THR C . n 
A 1 108 VAL 108 548 548 VAL VAL C . n 
A 1 109 SER 109 549 549 SER SER C . n 
A 1 110 SER 110 550 550 SER SER C . n 
B 2 1   MET 1   2   ?   ?   ?   A . n 
B 2 2   PRO 2   3   ?   ?   ?   A . n 
B 2 3   GLY 3   4   ?   ?   ?   A . n 
B 2 4   PRO 4   5   ?   ?   ?   A . n 
B 2 5   LEU 5   6   ?   ?   ?   A . n 
B 2 6   GLY 6   7   ?   ?   ?   A . n 
B 2 7   LEU 7   8   ?   ?   ?   A . n 
B 2 8   LEU 8   9   ?   ?   ?   A . n 
B 2 9   CYS 9   10  ?   ?   ?   A . n 
B 2 10  PHE 10  11  ?   ?   ?   A . n 
B 2 11  LEU 11  12  ?   ?   ?   A . n 
B 2 12  ALA 12  13  ?   ?   ?   A . n 
B 2 13  LEU 13  14  ?   ?   ?   A . n 
B 2 14  GLY 14  15  ?   ?   ?   A . n 
B 2 15  LEU 15  16  ?   ?   ?   A . n 
B 2 16  LEU 16  17  ?   ?   ?   A . n 
B 2 17  GLY 17  18  ?   ?   ?   A . n 
B 2 18  SER 18  19  ?   ?   ?   A . n 
B 2 19  ALA 19  20  ?   ?   ?   A . n 
B 2 20  GLY 20  21  ?   ?   ?   A . n 
B 2 21  PRO 21  22  ?   ?   ?   A . n 
B 2 22  SER 22  23  ?   ?   ?   A . n 
B 2 23  GLY 23  24  ?   ?   ?   A . n 
B 2 24  ALA 24  25  ?   ?   ?   A . n 
B 2 25  ALA 25  26  ?   ?   ?   A . n 
B 2 26  PRO 26  27  ?   ?   ?   A . n 
B 2 27  PRO 27  28  ?   ?   ?   A . n 
B 2 28  LEU 28  29  ?   ?   ?   A . n 
B 2 29  CYS 29  30  ?   ?   ?   A . n 
B 2 30  ALA 30  31  ?   ?   ?   A . n 
B 2 31  ALA 31  32  ?   ?   ?   A . n 
B 2 32  PRO 32  33  33  PRO PRO A . n 
B 2 33  CYS 33  34  34  CYS CYS A . n 
B 2 34  SER 34  35  35  SER SER A . n 
B 2 35  CYS 35  36  36  CYS CYS A . n 
B 2 36  ASP 36  37  37  ASP ASP A . n 
B 2 37  GLY 37  38  38  GLY GLY A . n 
B 2 38  ASP 38  39  39  ASP ASP A . n 
B 2 39  ARG 39  40  40  ARG ARG A . n 
B 2 40  ARG 40  41  41  ARG ARG A . n 
B 2 41  VAL 41  42  42  VAL VAL A . n 
B 2 42  ASP 42  43  43  ASP ASP A . n 
B 2 43  CYS 43  44  44  CYS CYS A . n 
B 2 44  SER 44  45  45  SER SER A . n 
B 2 45  GLY 45  46  46  GLY GLY A . n 
B 2 46  LYS 46  47  47  LYS LYS A . n 
B 2 47  GLY 47  48  48  GLY GLY A . n 
B 2 48  LEU 48  49  49  LEU LEU A . n 
B 2 49  THR 49  50  50  THR THR A . n 
B 2 50  ALA 50  51  51  ALA ALA A . n 
B 2 51  VAL 51  52  52  VAL VAL A . n 
B 2 52  PRO 52  53  53  PRO PRO A . n 
B 2 53  GLU 53  54  54  GLU GLU A . n 
B 2 54  GLY 54  55  55  GLY GLY A . n 
B 2 55  LEU 55  56  56  LEU LEU A . n 
B 2 56  SER 56  57  57  SER SER A . n 
B 2 57  ALA 57  58  58  ALA ALA A . n 
B 2 58  PHE 58  59  59  PHE PHE A . n 
B 2 59  THR 59  60  60  THR THR A . n 
B 2 60  GLN 60  61  61  GLN GLN A . n 
B 2 61  ALA 61  62  62  ALA ALA A . n 
B 2 62  LEU 62  63  63  LEU LEU A . n 
B 2 63  ASP 63  64  64  ASP ASP A . n 
B 2 64  ILE 64  65  65  ILE ILE A . n 
B 2 65  SER 65  66  66  SER SER A . n 
B 2 66  MET 66  67  67  MET MET A . n 
B 2 67  ASN 67  68  68  ASN ASN A . n 
B 2 68  ASN 68  69  69  ASN ASN A . n 
B 2 69  ILE 69  70  70  ILE ILE A . n 
B 2 70  THR 70  71  71  THR THR A . n 
B 2 71  GLN 71  72  72  GLN GLN A . n 
B 2 72  LEU 72  73  73  LEU LEU A . n 
B 2 73  PRO 73  74  74  PRO PRO A . n 
B 2 74  GLU 74  75  75  GLU GLU A . n 
B 2 75  ASP 75  76  76  ASP ASP A . n 
B 2 76  ALA 76  77  77  ALA ALA A . n 
B 2 77  PHE 77  78  78  PHE PHE A . n 
B 2 78  LYS 78  79  79  LYS ALA A . n 
B 2 79  ASN 79  80  80  ASN ASN A . n 
B 2 80  PHE 80  81  81  PHE PHE A . n 
B 2 81  PRO 81  82  82  PRO PRO A . n 
B 2 82  PHE 82  83  83  PHE PHE A . n 
B 2 83  LEU 83  84  84  LEU LEU A . n 
B 2 84  GLU 84  85  85  GLU GLU A . n 
B 2 85  GLU 85  86  86  GLU GLU A . n 
B 2 86  LEU 86  87  87  LEU LEU A . n 
B 2 87  GLN 87  88  88  GLN GLN A . n 
B 2 88  LEU 88  89  89  LEU LEU A . n 
B 2 89  ALA 89  90  90  ALA ALA A . n 
B 2 90  GLY 90  91  91  GLY GLY A . n 
B 2 91  ASN 91  92  92  ASN ASN A . n 
B 2 92  ASP 92  93  93  ASP ASP A . n 
B 2 93  LEU 93  94  94  LEU LEU A . n 
B 2 94  SER 94  95  95  SER SER A . n 
B 2 95  PHE 95  96  96  PHE PHE A . n 
B 2 96  ILE 96  97  97  ILE ILE A . n 
B 2 97  HIS 97  98  98  HIS HIS A . n 
B 2 98  PRO 98  99  99  PRO PRO A . n 
B 2 99  LYS 99  100 100 LYS LYS A . n 
B 2 100 ALA 100 101 101 ALA ALA A . n 
B 2 101 LEU 101 102 102 LEU LEU A . n 
B 2 102 SER 102 103 103 SER SER A . n 
B 2 103 GLY 103 104 104 GLY GLY A . n 
B 2 104 LEU 104 105 105 LEU LEU A . n 
B 2 105 LYS 105 106 106 LYS LYS A . n 
B 2 106 GLU 106 107 107 GLU GLU A . n 
B 2 107 LEU 107 108 108 LEU LEU A . n 
B 2 108 LYS 108 109 109 LYS LYS A . n 
B 2 109 VAL 109 110 110 VAL VAL A . n 
B 2 110 LEU 110 111 111 LEU LEU A . n 
B 2 111 THR 111 112 112 THR THR A . n 
B 2 112 LEU 112 113 113 LEU LEU A . n 
B 2 113 GLN 113 114 114 GLN GLN A . n 
B 2 114 ASN 114 115 115 ASN ASN A . n 
B 2 115 ASN 115 116 116 ASN ASN A . n 
B 2 116 GLN 116 117 117 GLN GLN A . n 
B 2 117 LEU 117 118 118 LEU LEU A . n 
B 2 118 LYS 118 119 119 LYS LYS A . n 
B 2 119 THR 119 120 120 THR THR A . n 
B 2 120 VAL 120 121 121 VAL VAL A . n 
B 2 121 PRO 121 122 122 PRO PRO A . n 
B 2 122 SER 122 123 123 SER SER A . n 
B 2 123 GLU 123 124 124 GLU GLU A . n 
B 2 124 ALA 124 125 125 ALA ALA A . n 
B 2 125 ILE 125 126 126 ILE ILE A . n 
B 2 126 ARG 126 127 127 ARG ARG A . n 
B 2 127 GLY 127 128 128 GLY GLY A . n 
B 2 128 LEU 128 129 129 LEU LEU A . n 
B 2 129 SER 129 130 130 SER SER A . n 
B 2 130 ALA 130 131 131 ALA ALA A . n 
B 2 131 LEU 131 132 132 LEU LEU A . n 
B 2 132 GLN 132 133 133 GLN GLN A . n 
B 2 133 SER 133 134 134 SER SER A . n 
B 2 134 LEU 134 135 135 LEU LEU A . n 
B 2 135 ARG 135 136 136 ARG ARG A . n 
B 2 136 LEU 136 137 137 LEU LEU A . n 
B 2 137 ASP 137 138 138 ASP ASP A . n 
B 2 138 ALA 138 139 139 ALA ALA A . n 
B 2 139 ASN 139 140 140 ASN ASN A . n 
B 2 140 HIS 140 141 141 HIS HIS A . n 
B 2 141 ILE 141 142 142 ILE ILE A . n 
B 2 142 THR 142 143 143 THR THR A . n 
B 2 143 SER 143 144 144 SER SER A . n 
B 2 144 VAL 144 145 145 VAL VAL A . n 
B 2 145 PRO 145 146 146 PRO PRO A . n 
B 2 146 GLU 146 147 147 GLU GLU A . n 
B 2 147 ASP 147 148 148 ASP ASP A . n 
B 2 148 SER 148 149 149 SER SER A . n 
B 2 149 PHE 149 150 150 PHE PHE A . n 
B 2 150 GLU 150 151 151 GLU GLU A . n 
B 2 151 GLY 151 152 152 GLY GLY A . n 
B 2 152 LEU 152 153 153 LEU LEU A . n 
B 2 153 VAL 153 154 154 VAL VAL A . n 
B 2 154 GLN 154 155 155 GLN GLN A . n 
B 2 155 LEU 155 156 156 LEU LEU A . n 
B 2 156 ARG 156 157 157 ARG ARG A . n 
B 2 157 HIS 157 158 158 HIS HIS A . n 
B 2 158 LEU 158 159 159 LEU LEU A . n 
B 2 159 TRP 159 160 160 TRP TRP A . n 
B 2 160 LEU 160 161 161 LEU LEU A . n 
B 2 161 ASP 161 162 162 ASP ASP A . n 
B 2 162 ASP 162 163 163 ASP ASP A . n 
B 2 163 ASN 163 164 164 ASN ASN A . n 
B 2 164 SER 164 165 165 SER SER A . n 
B 2 165 LEU 165 166 166 LEU LEU A . n 
B 2 166 THR 166 167 167 THR THR A . n 
B 2 167 GLU 167 168 168 GLU GLU A . n 
B 2 168 VAL 168 169 169 VAL VAL A . n 
B 2 169 PRO 169 170 170 PRO PRO A . n 
B 2 170 VAL 170 171 171 VAL VAL A . n 
B 2 171 HIS 171 172 172 HIS HIS A . n 
B 2 172 PRO 172 173 173 PRO PRO A . n 
B 2 173 LEU 173 174 174 LEU LEU A . n 
B 2 174 SER 174 175 175 SER SER A . n 
B 2 175 ASN 175 176 176 ASN ASN A . n 
B 2 176 LEU 176 177 177 LEU LEU A . n 
B 2 177 PRO 177 178 178 PRO PRO A . n 
B 2 178 THR 178 179 179 THR THR A . n 
B 2 179 LEU 179 180 180 LEU LEU A . n 
B 2 180 GLN 180 181 181 GLN GLN A . n 
B 2 181 ALA 181 182 182 ALA ALA A . n 
B 2 182 LEU 182 183 183 LEU LEU A . n 
B 2 183 THR 183 184 184 THR THR A . n 
B 2 184 LEU 184 185 185 LEU LEU A . n 
B 2 185 ALA 185 186 186 ALA ALA A . n 
B 2 186 LEU 186 187 187 LEU LEU A . n 
B 2 187 ASN 187 188 188 ASN ASN A . n 
B 2 188 LYS 188 189 189 LYS LYS A . n 
B 2 189 ILE 189 190 190 ILE ILE A . n 
B 2 190 SER 190 191 191 SER SER A . n 
B 2 191 SER 191 192 192 SER SER A . n 
B 2 192 ILE 192 193 193 ILE ILE A . n 
B 2 193 PRO 193 194 194 PRO PRO A . n 
B 2 194 ASP 194 195 195 ASP ASP A . n 
B 2 195 PHE 195 196 196 PHE PHE A . n 
B 2 196 ALA 196 197 197 ALA ALA A . n 
B 2 197 PHE 197 198 198 PHE PHE A . n 
B 2 198 THR 198 199 199 THR THR A . n 
B 2 199 ASN 199 200 200 ASN ASN A . n 
B 2 200 LEU 200 201 201 LEU LEU A . n 
B 2 201 SER 201 202 202 SER SER A . n 
B 2 202 SER 202 203 203 SER SER A . n 
B 2 203 LEU 203 204 204 LEU LEU A . n 
B 2 204 VAL 204 205 205 VAL VAL A . n 
B 2 205 VAL 205 206 206 VAL VAL A . n 
B 2 206 LEU 206 207 207 LEU LEU A . n 
B 2 207 HIS 207 208 208 HIS HIS A . n 
B 2 208 LEU 208 209 209 LEU LEU A . n 
B 2 209 HIS 209 210 210 HIS HIS A . n 
B 2 210 ASN 210 211 211 ASN ASN A . n 
B 2 211 ASN 211 212 212 ASN ASN A . n 
B 2 212 LYS 212 213 213 LYS LYS A . n 
B 2 213 ILE 213 214 214 ILE ILE A . n 
B 2 214 ARG 214 215 215 ARG ARG A . n 
B 2 215 SER 215 216 216 SER SER A . n 
B 2 216 LEU 216 217 217 LEU LEU A . n 
B 2 217 SER 217 218 218 SER SER A . n 
B 2 218 GLN 218 219 219 GLN GLN A . n 
B 2 219 HIS 219 220 220 HIS HIS A . n 
B 2 220 CYS 220 221 221 CYS CYS A . n 
B 2 221 PHE 221 222 222 PHE PHE A . n 
B 2 222 ASP 222 223 223 ASP ASP A . n 
B 2 223 GLY 223 224 224 GLY GLY A . n 
B 2 224 LEU 224 225 225 LEU LEU A . n 
B 2 225 ASP 225 226 226 ASP ASP A . n 
B 2 226 ASN 226 227 227 ASN ASN A . n 
B 2 227 LEU 227 228 228 LEU LEU A . n 
B 2 228 GLU 228 229 229 GLU GLU A . n 
B 2 229 THR 229 230 230 THR THR A . n 
B 2 230 LEU 230 231 231 LEU LEU A . n 
B 2 231 ASP 231 232 232 ASP ASP A . n 
B 2 232 LEU 232 233 233 LEU LEU A . n 
B 2 233 ASN 233 234 234 ASN ASN A . n 
B 2 234 TYR 234 235 235 TYR TYR A . n 
B 2 235 ASN 235 236 236 ASN ASN A . n 
B 2 236 ASN 236 237 237 ASN ASN A . n 
B 2 237 LEU 237 238 238 LEU LEU A . n 
B 2 238 GLY 238 239 239 GLY GLY A . n 
B 2 239 GLU 239 240 240 GLU GLU A . n 
B 2 240 PHE 240 241 241 PHE PHE A . n 
B 2 241 PRO 241 242 242 PRO PRO A . n 
B 2 242 GLN 242 243 243 GLN GLN A . n 
B 2 243 ALA 243 244 244 ALA ALA A . n 
B 2 244 ILE 244 245 245 ILE ILE A . n 
B 2 245 LYS 245 246 246 LYS LYS A . n 
B 2 246 ALA 246 247 247 ALA ALA A . n 
B 2 247 LEU 247 248 248 LEU LEU A . n 
B 2 248 PRO 248 249 249 PRO PRO A . n 
B 2 249 SER 249 250 250 SER SER A . n 
B 2 250 LEU 250 251 251 LEU LEU A . n 
B 2 251 LYS 251 252 252 LYS LYS A . n 
B 2 252 GLU 252 253 253 GLU GLU A . n 
B 2 253 LEU 253 254 254 LEU LEU A . n 
B 2 254 GLY 254 255 255 GLY GLY A . n 
B 2 255 PHE 255 256 256 PHE PHE A . n 
B 2 256 HIS 256 257 257 HIS HIS A . n 
B 2 257 SER 257 258 258 SER SER A . n 
B 2 258 ASN 258 259 259 ASN ASN A . n 
B 2 259 SER 259 260 260 SER SER A . n 
B 2 260 ILE 260 261 261 ILE ILE A . n 
B 2 261 SER 261 262 262 SER SER A . n 
B 2 262 VAL 262 263 263 VAL VAL A . n 
B 2 263 ILE 263 264 264 ILE ILE A . n 
B 2 264 PRO 264 265 265 PRO PRO A . n 
B 2 265 ASP 265 266 266 ASP ASP A . n 
B 2 266 GLY 266 267 267 GLY GLY A . n 
B 2 267 ALA 267 268 268 ALA ALA A . n 
B 2 268 PHE 268 269 269 PHE PHE A . n 
B 2 269 ASP 269 270 270 ASP ASP A . n 
B 2 270 GLY 270 271 271 GLY GLY A . n 
B 2 271 ASN 271 272 272 ASN ASN A . n 
B 2 272 PRO 272 273 273 PRO PRO A . n 
B 2 273 LEU 273 274 274 LEU LEU A . n 
B 2 274 LEU 274 275 275 LEU LEU A . n 
B 2 275 ARG 275 276 276 ARG ARG A . n 
B 2 276 THR 276 277 277 THR THR A . n 
B 2 277 ILE 277 278 278 ILE ILE A . n 
B 2 278 HIS 278 279 279 HIS HIS A . n 
B 2 279 LEU 279 280 280 LEU LEU A . n 
B 2 280 TYR 280 281 281 TYR TYR A . n 
B 2 281 ASP 281 282 282 ASP ASP A . n 
B 2 282 ASN 282 283 283 ASN ASN A . n 
B 2 283 PRO 283 284 284 PRO PRO A . n 
B 2 284 LEU 284 285 285 LEU LEU A . n 
B 2 285 SER 285 286 286 SER SER A . n 
B 2 286 PHE 286 287 287 PHE PHE A . n 
B 2 287 VAL 287 288 288 VAL VAL A . n 
B 2 288 GLY 288 289 289 GLY GLY A . n 
B 2 289 ASN 289 290 290 ASN ASN A . n 
B 2 290 SER 290 291 291 SER SER A . n 
B 2 291 ALA 291 292 292 ALA ALA A . n 
B 2 292 PHE 292 293 293 PHE PHE A . n 
B 2 293 HIS 293 294 294 HIS HIS A . n 
B 2 294 ASN 294 295 295 ASN ASN A . n 
B 2 295 LEU 295 296 296 LEU LEU A . n 
B 2 296 SER 296 297 297 SER SER A . n 
B 2 297 ASP 297 298 298 ASP ASP A . n 
B 2 298 LEU 298 299 299 LEU LEU A . n 
B 2 299 HIS 299 300 300 HIS HIS A . n 
B 2 300 SER 300 301 301 SER SER A . n 
B 2 301 LEU 301 302 302 LEU LEU A . n 
B 2 302 VAL 302 303 303 VAL VAL A . n 
B 2 303 ILE 303 304 304 ILE ILE A . n 
B 2 304 ARG 304 305 305 ARG ARG A . n 
B 2 305 GLY 305 306 306 GLY GLY A . n 
B 2 306 ALA 306 307 307 ALA ALA A . n 
B 2 307 SER 307 308 308 SER SER A . n 
B 2 308 MET 308 309 309 MET MET A . n 
B 2 309 VAL 309 310 310 VAL VAL A . n 
B 2 310 GLN 310 311 311 GLN GLN A . n 
B 2 311 GLN 311 312 312 GLN GLN A . n 
B 2 312 PHE 312 313 313 PHE PHE A . n 
B 2 313 PRO 313 314 314 PRO PRO A . n 
B 2 314 ASN 314 315 315 ASN ASN A . n 
B 2 315 LEU 315 316 316 LEU LEU A . n 
B 2 316 THR 316 317 317 THR THR A . n 
B 2 317 GLY 317 318 318 GLY GLY A . n 
B 2 318 THR 318 319 319 THR THR A . n 
B 2 319 VAL 319 320 320 VAL VAL A . n 
B 2 320 HIS 320 321 321 HIS HIS A . n 
B 2 321 LEU 321 322 322 LEU LEU A . n 
B 2 322 GLU 322 323 323 GLU GLU A . n 
B 2 323 SER 323 324 324 SER SER A . n 
B 2 324 LEU 324 325 325 LEU LEU A . n 
B 2 325 THR 325 326 326 THR THR A . n 
B 2 326 LEU 326 327 327 LEU LEU A . n 
B 2 327 THR 327 328 328 THR THR A . n 
B 2 328 GLY 328 329 329 GLY GLY A . n 
B 2 329 THR 329 330 330 THR THR A . n 
B 2 330 LYS 330 331 331 LYS LYS A . n 
B 2 331 ILE 331 332 332 ILE ILE A . n 
B 2 332 SER 332 333 333 SER SER A . n 
B 2 333 SER 333 334 334 SER SER A . n 
B 2 334 ILE 334 335 335 ILE ILE A . n 
B 2 335 PRO 335 336 336 PRO PRO A . n 
B 2 336 ASN 336 337 337 ASN ASN A . n 
B 2 337 ASN 337 338 338 ASN ASN A . n 
B 2 338 LEU 338 339 339 LEU LEU A . n 
B 2 339 CYS 339 340 340 CYS CYS A . n 
B 2 340 GLN 340 341 341 GLN GLN A . n 
B 2 341 GLU 341 342 342 GLU GLU A . n 
B 2 342 GLN 342 343 343 GLN GLN A . n 
B 2 343 LYS 343 344 344 LYS LYS A . n 
B 2 344 MET 344 345 345 MET MET A . n 
B 2 345 LEU 345 346 346 LEU LEU A . n 
B 2 346 ARG 346 347 347 ARG ARG A . n 
B 2 347 THR 347 348 348 THR THR A . n 
B 2 348 LEU 348 349 349 LEU LEU A . n 
B 2 349 ASP 349 350 350 ASP ASP A . n 
B 2 350 LEU 350 351 351 LEU LEU A . n 
B 2 351 SER 351 352 352 SER SER A . n 
B 2 352 TYR 352 353 353 TYR TYR A . n 
B 2 353 ASN 353 354 354 ASN ASN A . n 
B 2 354 ASN 354 355 355 ASN ASN A . n 
B 2 355 ILE 355 356 356 ILE ILE A . n 
B 2 356 ARG 356 357 357 ARG ARG A . n 
B 2 357 ASP 357 358 358 ASP ASP A . n 
B 2 358 LEU 358 359 359 LEU LEU A . n 
B 2 359 PRO 359 360 360 PRO PRO A . n 
B 2 360 SER 360 361 361 SER SER A . n 
B 2 361 PHE 361 362 362 PHE PHE A . n 
B 2 362 ASN 362 363 363 ASN ASN A . n 
B 2 363 GLY 363 364 364 GLY GLY A . n 
B 2 364 CYS 364 365 365 CYS CYS A . n 
B 2 365 HIS 365 366 366 HIS HIS A . n 
B 2 366 ALA 366 367 367 ALA ALA A . n 
B 2 367 LEU 367 368 368 LEU LEU A . n 
B 2 368 GLU 368 369 369 GLU GLU A . n 
B 2 369 GLU 369 370 370 GLU GLU A . n 
B 2 370 ILE 370 371 371 ILE ILE A . n 
B 2 371 SER 371 372 372 SER SER A . n 
B 2 372 LEU 372 373 373 LEU LEU A . n 
B 2 373 GLN 373 374 374 GLN GLN A . n 
B 2 374 ARG 374 375 375 ARG ARG A . n 
B 2 375 ASN 375 376 376 ASN ASN A . n 
B 2 376 GLN 376 377 377 GLN GLN A . n 
B 2 377 ILE 377 378 378 ILE ILE A . n 
B 2 378 TYR 378 379 379 TYR TYR A . n 
B 2 379 GLN 379 380 380 GLN GLN A . n 
B 2 380 ILE 380 381 381 ILE ILE A . n 
B 2 381 LYS 381 382 382 LYS LYS A . n 
B 2 382 GLU 382 383 383 GLU GLU A . n 
B 2 383 GLY 383 384 384 GLY GLY A . n 
B 2 384 THR 384 385 385 THR THR A . n 
B 2 385 PHE 385 386 386 PHE PHE A . n 
B 2 386 GLN 386 387 387 GLN GLN A . n 
B 2 387 GLY 387 388 388 GLY GLY A . n 
B 2 388 LEU 388 389 389 LEU LEU A . n 
B 2 389 ILE 389 390 390 ILE ILE A . n 
B 2 390 SER 390 391 391 SER SER A . n 
B 2 391 LEU 391 392 392 LEU LEU A . n 
B 2 392 ARG 392 393 393 ARG ARG A . n 
B 2 393 ILE 393 394 394 ILE ILE A . n 
B 2 394 LEU 394 395 395 LEU LEU A . n 
B 2 395 ASP 395 396 396 ASP ASP A . n 
B 2 396 LEU 396 397 397 LEU LEU A . n 
B 2 397 SER 397 398 398 SER SER A . n 
B 2 398 ARG 398 399 399 ARG ARG A . n 
B 2 399 ASN 399 400 400 ASN ASN A . n 
B 2 400 LEU 400 401 401 LEU LEU A . n 
B 2 401 ILE 401 402 402 ILE ILE A . n 
B 2 402 HIS 402 403 403 HIS HIS A . n 
B 2 403 GLU 403 404 404 GLU GLU A . n 
B 2 404 ILE 404 405 405 ILE ILE A . n 
B 2 405 HIS 405 406 406 HIS HIS A . n 
B 2 406 SER 406 407 407 SER SER A . n 
B 2 407 ARG 407 408 408 ARG ARG A . n 
B 2 408 ALA 408 409 409 ALA ALA A . n 
B 2 409 PHE 409 410 410 PHE PHE A . n 
B 2 410 ALA 410 411 411 ALA ALA A . n 
B 2 411 THR 411 412 412 THR THR A . n 
B 2 412 LEU 412 413 413 LEU LEU A . n 
B 2 413 GLY 413 414 414 GLY GLY A . n 
B 2 414 PRO 414 415 415 PRO PRO A . n 
B 2 415 ILE 415 416 416 ILE ILE A . n 
B 2 416 THR 416 417 417 THR THR A . n 
B 2 417 ASN 417 418 418 ASN ASN A . n 
B 2 418 LEU 418 419 419 LEU LEU A . n 
B 2 419 ASP 419 420 420 ASP ASP A . n 
B 2 420 VAL 420 421 421 VAL VAL A . n 
B 2 421 SER 421 422 422 SER SER A . n 
B 2 422 PHE 422 423 423 PHE PHE A . n 
B 2 423 ASN 423 424 424 ASN ASN A . n 
B 2 424 GLU 424 425 425 GLU GLU A . n 
B 2 425 LEU 425 426 426 LEU LEU A . n 
B 2 426 THR 426 427 427 THR THR A . n 
B 2 427 SER 427 428 428 SER SER A . n 
B 2 428 PHE 428 429 429 PHE PHE A . n 
B 2 429 PRO 429 430 430 PRO PRO A . n 
B 2 430 THR 430 431 431 THR THR A . n 
B 2 431 GLU 431 432 432 GLU GLU A . n 
B 2 432 GLY 432 433 433 GLY GLY A . n 
B 2 433 LEU 433 434 434 LEU LEU A . n 
B 2 434 ASN 434 435 435 ASN ASN A . n 
B 2 435 GLY 435 436 436 GLY GLY A . n 
B 2 436 LEU 436 437 437 LEU LEU A . n 
B 2 437 ASN 437 438 438 ASN ASN A . n 
B 2 438 GLN 438 439 439 GLN GLN A . n 
B 2 439 LEU 439 440 440 LEU LEU A . n 
B 2 440 LYS 440 441 441 LYS LYS A . n 
B 2 441 LEU 441 442 442 LEU LEU A . n 
B 2 442 VAL 442 443 443 VAL VAL A . n 
B 2 443 GLY 443 444 444 GLY GLY A . n 
B 2 444 ASN 444 445 445 ASN ASN A . n 
B 2 445 PHE 445 446 446 PHE PHE A . n 
B 2 446 LYS 446 447 447 LYS LYS A . n 
B 2 447 LEU 447 448 448 LEU LEU A . n 
B 2 448 LYS 448 449 449 LYS LYS A . n 
B 2 449 GLU 449 450 450 GLU GLU A . n 
B 2 450 ALA 450 451 451 ALA ALA A . n 
B 2 451 LEU 451 452 452 LEU LEU A . n 
B 2 452 ALA 452 453 453 ALA ALA A . n 
B 2 453 ALA 453 454 454 ALA ALA A . n 
B 2 454 LYS 454 455 455 LYS LYS A . n 
B 2 455 ASP 455 456 456 ASP ASP A . n 
B 2 456 PHE 456 457 457 PHE PHE A . n 
B 2 457 VAL 457 458 458 VAL VAL A . n 
B 2 458 ASN 458 459 459 ASN ASN A . n 
B 2 459 LEU 459 460 460 LEU LEU A . n 
B 2 460 ARG 460 461 461 ARG ARG A . n 
B 2 461 SER 461 462 462 SER SER A . n 
B 2 462 LEU 462 463 463 LEU LEU A . n 
B 2 463 SER 463 464 464 SER SER A . n 
B 2 464 VAL 464 465 465 VAL VAL A . n 
B 2 465 PRO 465 466 466 PRO PRO A . n 
B 2 466 TYR 466 467 467 TYR TYR A . n 
B 2 467 ALA 467 468 468 ALA ALA A . n 
B 2 468 TYR 468 469 469 TYR TYR A . n 
B 2 469 GLN 469 470 470 GLN GLN A . n 
B 2 470 CYS 470 471 471 CYS CYS A . n 
B 2 471 CYS 471 472 472 CYS CYS A . n 
B 2 472 ALA 472 473 473 ALA ALA A . n 
B 2 473 PHE 473 474 474 PHE PHE A . n 
B 2 474 TRP 474 475 475 TRP ALA A . n 
B 2 475 GLY 475 476 476 GLY ALA A . n 
B 2 476 CYS 476 477 477 CYS ALA A . n 
B 2 477 ASP 477 478 478 ASP ALA A . n 
B 2 478 SER 478 479 479 SER ALA A . n 
B 2 479 TYR 479 479 ?   ?   ?   A A n 
B 2 480 ALA 480 479 ?   ?   ?   A B n 
B 2 481 ASN 481 479 ?   ?   ?   A C n 
B 2 482 LEU 482 479 ?   ?   ?   A D n 
B 2 483 ASN 483 479 ?   ?   ?   A E n 
B 2 484 THR 484 479 ?   ?   ?   A F n 
B 2 485 GLU 485 479 ?   ?   ?   A G n 
B 2 486 ASP 486 479 ?   ?   ?   A H n 
B 2 487 ASN 487 479 ?   ?   ?   A I n 
B 2 488 SER 488 479 ?   ?   ?   A J n 
B 2 489 LEU 489 479 ?   ?   ?   A K n 
B 2 490 GLN 490 479 ?   ?   ?   A L n 
B 2 491 ASP 491 479 ?   ?   ?   A M n 
B 2 492 HIS 492 479 ?   ?   ?   A N n 
B 2 493 SER 493 479 ?   ?   ?   A O n 
B 2 494 VAL 494 479 ?   ?   ?   A P n 
B 2 495 ALA 495 479 ?   ?   ?   A Q n 
B 2 496 GLN 496 479 ?   ?   ?   A R n 
B 2 497 GLU 497 479 ?   ?   ?   A S n 
B 2 498 LYS 498 479 ?   ?   ?   A T n 
B 2 499 GLY 499 479 ?   ?   ?   A U n 
B 2 500 THR 500 479 ?   ?   ?   A V n 
B 2 501 ALA 501 479 ?   ?   ?   A W n 
B 2 502 ASP 502 479 ?   ?   ?   A X n 
B 2 503 ALA 503 479 ?   ?   ?   A Y n 
B 2 504 ALA 504 479 ?   ?   ?   A Z n 
B 2 505 ASN 505 480 ?   ?   ?   A A n 
B 2 506 VAL 506 480 ?   ?   ?   A B n 
B 2 507 THR 507 480 ?   ?   ?   A C n 
B 2 508 SER 508 480 ?   ?   ?   A D n 
B 2 509 THR 509 480 ?   ?   ?   A E n 
B 2 510 LEU 510 480 ?   ?   ?   A F n 
B 2 511 GLU 511 480 ?   ?   ?   A G n 
B 2 512 ASN 512 480 ?   ?   ?   A H n 
B 2 513 GLU 513 480 ?   ?   ?   A I n 
B 2 514 GLU 514 480 ?   ?   ?   A J n 
B 2 515 HIS 515 480 ?   ?   ?   A K n 
B 2 516 SER 516 516 516 SER ALA A . n 
B 2 517 GLN 517 517 517 GLN ALA A . n 
B 2 518 ILE 518 518 518 ILE ALA A . n 
B 2 519 ILE 519 519 519 ILE ALA A . n 
B 2 520 ILE 520 520 520 ILE ILE A . n 
B 2 521 HIS 521 521 521 HIS HIS A . n 
B 2 522 CYS 522 522 522 CYS CYS A . n 
B 2 523 THR 523 523 523 THR THR A . n 
B 2 524 PRO 524 524 524 PRO PRO A . n 
B 2 525 SER 525 525 525 SER SER A . n 
B 2 526 THR 526 526 526 THR THR A . n 
B 2 527 GLY 527 527 527 GLY GLY A . n 
B 2 528 ALA 528 528 528 ALA ALA A . n 
B 2 529 PHE 529 529 529 PHE PHE A . n 
B 2 530 LYS 530 530 530 LYS LYS A . n 
B 2 531 PRO 531 531 531 PRO PRO A . n 
B 2 532 CYS 532 532 532 CYS CYS A . n 
B 2 533 GLU 533 533 533 GLU GLU A . n 
B 2 534 TYR 534 534 534 TYR TYR A . n 
B 2 535 LEU 535 535 535 LEU LEU A . n 
B 2 536 LEU 536 536 536 LEU LEU A . n 
B 2 537 GLY 537 537 537 GLY GLY A . n 
B 2 538 SER 538 538 538 SER SER A . n 
B 2 539 TRP 539 539 539 TRP TRP A . n 
B 2 540 MET 540 540 540 MET MET A . n 
B 2 541 ILE 541 541 541 ILE ILE A . n 
B 2 542 ARG 542 542 542 ARG ARG A . n 
B 2 543 LEU 543 543 543 LEU LEU A . n 
B 2 544 THR 544 544 544 THR THR A . n 
B 2 545 VAL 545 545 545 VAL VAL A . n 
B 2 546 TRP 546 546 546 TRP TRP A . n 
B 2 547 PHE 547 547 547 PHE PHE A . n 
B 2 548 ILE 548 548 548 ILE ILE A . n 
B 2 549 PHE 549 549 549 PHE PHE A . n 
B 2 550 LEU 550 550 550 LEU LEU A . n 
B 2 551 VAL 551 551 551 VAL VAL A . n 
B 2 552 ALA 552 552 552 ALA ALA A . n 
B 2 553 LEU 553 553 553 LEU LEU A . n 
B 2 554 PHE 554 554 554 PHE PHE A . n 
B 2 555 PHE 555 555 555 PHE PHE A . n 
B 2 556 ASN 556 556 556 ASN ASN A . n 
B 2 557 LEU 557 557 557 LEU LEU A . n 
B 2 558 LEU 558 558 558 LEU LEU A . n 
B 2 559 VAL 559 559 559 VAL VAL A . n 
B 2 560 ILE 560 560 560 ILE ILE A . n 
B 2 561 LEU 561 561 561 LEU LEU A . n 
B 2 562 THR 562 562 562 THR THR A . n 
B 2 563 THR 563 563 563 THR THR A . n 
B 2 564 PHE 564 564 564 PHE PHE A . n 
B 2 565 ALA 565 565 565 ALA ALA A . n 
B 2 566 SER 566 566 566 SER SER A . n 
B 2 567 CYS 567 567 567 CYS CYS A . n 
B 2 568 THR 568 568 568 THR THR A . n 
B 2 569 SER 569 569 569 SER SER A . n 
B 2 570 LEU 570 570 570 LEU LEU A . n 
B 2 571 PRO 571 571 571 PRO PRO A . n 
B 2 572 SER 572 572 572 SER SER A . n 
B 2 573 SER 573 573 573 SER SER A . n 
B 2 574 LYS 574 574 574 LYS LYS A . n 
B 2 575 LEU 575 575 575 LEU LEU A . n 
B 2 576 PHE 576 576 576 PHE PHE A . n 
B 2 577 ILE 577 577 577 ILE ILE A . n 
B 2 578 GLY 578 578 578 GLY GLY A . n 
B 2 579 LEU 579 579 579 LEU LEU A . n 
B 2 580 ILE 580 580 580 ILE ILE A . n 
B 2 581 SER 581 581 581 SER SER A . n 
B 2 582 VAL 582 582 582 VAL VAL A . n 
B 2 583 SER 583 583 583 SER SER A . n 
B 2 584 ASN 584 584 584 ASN ASN A . n 
B 2 585 LEU 585 585 585 LEU LEU A . n 
B 2 586 PHE 586 586 586 PHE PHE A . n 
B 2 587 MET 587 587 587 MET MET A . n 
B 2 588 GLY 588 588 588 GLY GLY A . n 
B 2 589 ILE 589 589 589 ILE ILE A . n 
B 2 590 TYR 590 590 590 TYR TYR A . n 
B 2 591 THR 591 591 591 THR THR A . n 
B 2 592 GLY 592 592 592 GLY GLY A . n 
B 2 593 ILE 593 593 593 ILE ILE A . n 
B 2 594 LEU 594 594 594 LEU LEU A . n 
B 2 595 THR 595 595 595 THR THR A . n 
B 2 596 PHE 596 596 596 PHE PHE A . n 
B 2 597 LEU 597 597 597 LEU LEU A . n 
B 2 598 ASP 598 598 598 ASP ASP A . n 
B 2 599 ALA 599 599 599 ALA ALA A . n 
B 2 600 VAL 600 600 600 VAL VAL A . n 
B 2 601 SER 601 601 601 SER SER A . n 
B 2 602 TRP 602 602 602 TRP TRP A . n 
B 2 603 GLY 603 603 603 GLY GLY A . n 
B 2 604 ARG 604 604 604 ARG ARG A . n 
B 2 605 PHE 605 605 605 PHE PHE A . n 
B 2 606 ALA 606 606 606 ALA ALA A . n 
B 2 607 GLU 607 607 607 GLU GLU A . n 
B 2 608 PHE 608 608 608 PHE PHE A . n 
B 2 609 GLY 609 609 609 GLY GLY A . n 
B 2 610 ILE 610 610 610 ILE ILE A . n 
B 2 611 TRP 611 611 611 TRP TRP A . n 
B 2 612 TRP 612 612 612 TRP TRP A . n 
B 2 613 GLU 613 613 613 GLU GLU A . n 
B 2 614 THR 614 614 614 THR THR A . n 
B 2 615 GLY 615 615 615 GLY GLY A . n 
B 2 616 SER 616 616 616 SER SER A . n 
B 2 617 GLY 617 617 617 GLY GLY A . n 
B 2 618 CYS 618 618 618 CYS CYS A . n 
B 2 619 LYS 619 619 619 LYS LYS A . n 
B 2 620 VAL 620 620 620 VAL VAL A . n 
B 2 621 ALA 621 621 621 ALA ALA A . n 
B 2 622 GLY 622 622 622 GLY GLY A . n 
B 2 623 PHE 623 623 623 PHE PHE A . n 
B 2 624 LEU 624 624 624 LEU LEU A . n 
B 2 625 ALA 625 625 625 ALA ALA A . n 
B 2 626 VAL 626 626 626 VAL VAL A . n 
B 2 627 PHE 627 627 627 PHE PHE A . n 
B 2 628 SER 628 628 628 SER SER A . n 
B 2 629 SER 629 629 629 SER SER A . n 
B 2 630 GLU 630 630 630 GLU GLU A . n 
B 2 631 SER 631 631 631 SER SER A . n 
B 2 632 ALA 632 632 632 ALA ALA A . n 
B 2 633 ILE 633 633 633 ILE ILE A . n 
B 2 634 PHE 634 634 634 PHE PHE A . n 
B 2 635 LEU 635 635 635 LEU LEU A . n 
B 2 636 LEU 636 636 636 LEU LEU A . n 
B 2 637 MET 637 637 637 MET MET A . n 
B 2 638 LEU 638 638 638 LEU LEU A . n 
B 2 639 ALA 639 639 639 ALA ALA A . n 
B 2 640 THR 640 640 640 THR THR A . n 
B 2 641 VAL 641 641 641 VAL VAL A . n 
B 2 642 GLU 642 642 642 GLU GLU A . n 
B 2 643 ARG 643 643 643 ARG ARG A . n 
B 2 644 SER 644 644 644 SER SER A . n 
B 2 645 LEU 645 645 645 LEU LEU A . n 
B 2 646 SER 646 646 646 SER SER A . n 
B 2 647 ALA 647 647 647 ALA ALA A . n 
B 2 648 LYS 648 648 648 LYS LYS A . n 
B 2 649 ASP 649 649 649 ASP ASP A . n 
B 2 650 ILE 650 650 ?   ?   ?   A . n 
B 2 651 MET 651 651 ?   ?   ?   A . n 
B 2 652 LYS 652 652 ?   ?   ?   A . n 
B 2 653 ASN 653 653 ?   ?   ?   A . n 
B 2 654 GLY 654 654 ?   ?   ?   A . n 
B 2 655 LYS 655 655 ?   ?   ?   A . n 
B 2 656 SER 656 656 ?   ?   ?   A . n 
B 2 657 ASN 657 657 657 ASN ASN A . n 
B 2 658 HIS 658 658 658 HIS HIS A . n 
B 2 659 LEU 659 659 659 LEU LEU A . n 
B 2 660 LYS 660 660 660 LYS LYS A . n 
B 2 661 GLN 661 661 661 GLN GLN A . n 
B 2 662 PHE 662 662 662 PHE PHE A . n 
B 2 663 ARG 663 663 663 ARG ARG A . n 
B 2 664 VAL 664 664 664 VAL VAL A . n 
B 2 665 ALA 665 665 665 ALA ALA A . n 
B 2 666 ALA 666 666 666 ALA ALA A . n 
B 2 667 LEU 667 667 667 LEU LEU A . n 
B 2 668 LEU 668 668 668 LEU LEU A . n 
B 2 669 ALA 669 669 669 ALA ALA A . n 
B 2 670 PHE 670 670 670 PHE PHE A . n 
B 2 671 LEU 671 671 671 LEU LEU A . n 
B 2 672 GLY 672 672 672 GLY GLY A . n 
B 2 673 ALA 673 673 673 ALA ALA A . n 
B 2 674 THR 674 674 674 THR THR A . n 
B 2 675 VAL 675 675 675 VAL VAL A . n 
B 2 676 ALA 676 676 676 ALA ALA A . n 
B 2 677 GLY 677 677 677 GLY GLY A . n 
B 2 678 CYS 678 678 678 CYS CYS A . n 
B 2 679 PHE 679 679 679 PHE PHE A . n 
B 2 680 PRO 680 680 680 PRO PRO A . n 
B 2 681 LEU 681 681 681 LEU LEU A . n 
B 2 682 PHE 682 682 682 PHE PHE A . n 
B 2 683 HIS 683 683 683 HIS HIS A . n 
B 2 684 ARG 684 684 684 ARG ARG A . n 
B 2 685 GLY 685 685 685 GLY GLY A . n 
B 2 686 GLU 686 686 686 GLU GLU A . n 
B 2 687 TYR 687 687 687 TYR TYR A . n 
B 2 688 SER 688 688 688 SER SER A . n 
B 2 689 ALA 689 689 689 ALA ALA A . n 
B 2 690 SER 690 690 690 SER SER A . n 
B 2 691 PRO 691 691 691 PRO PRO A . n 
B 2 692 LEU 692 692 692 LEU LEU A . n 
B 2 693 CYS 693 693 693 CYS CYS A . n 
B 2 694 LEU 694 694 694 LEU LEU A . n 
B 2 695 PRO 695 695 695 PRO PRO A . n 
B 2 696 PHE 696 696 696 PHE PHE A . n 
B 2 697 PRO 697 697 697 PRO PRO A . n 
B 2 698 THR 698 698 698 THR THR A . n 
B 2 699 GLY 699 699 699 GLY GLY A . n 
B 2 700 GLU 700 700 700 GLU GLU A . n 
B 2 701 THR 701 701 701 THR THR A . n 
B 2 702 PRO 702 702 702 PRO PRO A . n 
B 2 703 SER 703 703 703 SER SER A . n 
B 2 704 LEU 704 704 704 LEU LEU A . n 
B 2 705 GLY 705 705 705 GLY GLY A . n 
B 2 706 PHE 706 706 706 PHE PHE A . n 
B 2 707 THR 707 707 707 THR THR A . n 
B 2 708 VAL 708 708 708 VAL VAL A . n 
B 2 709 THR 709 709 709 THR THR A . n 
B 2 710 LEU 710 710 710 LEU LEU A . n 
B 2 711 VAL 711 711 711 VAL VAL A . n 
B 2 712 LEU 712 712 712 LEU LEU A . n 
B 2 713 LEU 713 713 713 LEU LEU A . n 
B 2 714 ASN 714 714 714 ASN ASN A . n 
B 2 715 SER 715 715 715 SER SER A . n 
B 2 716 LEU 716 716 716 LEU LEU A . n 
B 2 717 ALA 717 717 717 ALA ALA A . n 
B 2 718 PHE 718 718 718 PHE PHE A . n 
B 2 719 LEU 719 719 719 LEU LEU A . n 
B 2 720 LEU 720 720 720 LEU LEU A . n 
B 2 721 MET 721 721 721 MET MET A . n 
B 2 722 ALA 722 722 722 ALA ALA A . n 
B 2 723 VAL 723 723 723 VAL VAL A . n 
B 2 724 ILE 724 724 724 ILE ILE A . n 
B 2 725 TYR 725 725 725 TYR TYR A . n 
B 2 726 THR 726 726 726 THR THR A . n 
B 2 727 LYS 727 727 727 LYS LYS A . n 
B 2 728 LEU 728 728 728 LEU LEU A . n 
B 2 729 TYR 729 729 729 TYR TYR A . n 
B 2 730 CYS 730 730 730 CYS CYS A . n 
B 2 731 ASN 731 731 731 ASN ASN A . n 
B 2 732 LEU 732 732 732 LEU LEU A . n 
B 2 733 GLU 733 733 ?   ?   ?   A . n 
B 2 734 LYS 734 734 ?   ?   ?   A . n 
B 2 735 GLU 735 735 ?   ?   ?   A . n 
B 2 736 ASP 736 736 ?   ?   ?   A . n 
B 2 737 LEU 737 737 ?   ?   ?   A . n 
B 2 738 SER 738 738 ?   ?   ?   A . n 
B 2 739 GLU 739 739 ?   ?   ?   A . n 
B 2 740 ASN 740 740 ?   ?   ?   A . n 
B 2 741 SER 741 741 741 SER SER A . n 
B 2 742 GLN 742 742 742 GLN GLN A . n 
B 2 743 SER 743 743 743 SER SER A . n 
B 2 744 SER 744 744 744 SER SER A . n 
B 2 745 MET 745 745 745 MET MET A . n 
B 2 746 ILE 746 746 746 ILE ILE A . n 
B 2 747 LYS 747 747 747 LYS LYS A . n 
B 2 748 HIS 748 748 748 HIS HIS A . n 
B 2 749 VAL 749 749 749 VAL VAL A . n 
B 2 750 ALA 750 750 750 ALA ALA A . n 
B 2 751 TRP 751 751 751 TRP TRP A . n 
B 2 752 LEU 752 752 752 LEU LEU A . n 
B 2 753 ILE 753 753 753 ILE ILE A . n 
B 2 754 PHE 754 754 754 PHE PHE A . n 
B 2 755 THR 755 755 755 THR THR A . n 
B 2 756 ASN 756 756 756 ASN ASN A . n 
B 2 757 CYS 757 757 757 CYS CYS A . n 
B 2 758 ILE 758 758 758 ILE ILE A . n 
B 2 759 PHE 759 759 759 PHE PHE A . n 
B 2 760 PHE 760 760 760 PHE PHE A . n 
B 2 761 CYS 761 761 761 CYS CYS A . n 
B 2 762 PRO 762 762 762 PRO PRO A . n 
B 2 763 VAL 763 763 763 VAL VAL A . n 
B 2 764 ALA 764 764 764 ALA ALA A . n 
B 2 765 PHE 765 765 765 PHE PHE A . n 
B 2 766 PHE 766 766 766 PHE PHE A . n 
B 2 767 SER 767 767 767 SER SER A . n 
B 2 768 PHE 768 768 768 PHE PHE A . n 
B 2 769 ALA 769 769 769 ALA ALA A . n 
B 2 770 PRO 770 770 770 PRO PRO A . n 
B 2 771 LEU 771 771 771 LEU LEU A . n 
B 2 772 ILE 772 772 772 ILE ILE A . n 
B 2 773 THR 773 773 773 THR THR A . n 
B 2 774 ALA 774 774 774 ALA ALA A . n 
B 2 775 ILE 775 775 775 ILE ILE A . n 
B 2 776 SER 776 776 776 SER SER A . n 
B 2 777 ILE 777 777 777 ILE ILE A . n 
B 2 778 SER 778 778 778 SER SER A . n 
B 2 779 PRO 779 779 779 PRO PRO A . n 
B 2 780 GLU 780 780 780 GLU GLU A . n 
B 2 781 ILE 781 781 781 ILE ILE A . n 
B 2 782 MET 782 782 782 MET MET A . n 
B 2 783 LYS 783 783 783 LYS LYS A . n 
B 2 784 SER 784 784 784 SER SER A . n 
B 2 785 VAL 785 785 785 VAL VAL A . n 
B 2 786 THR 786 786 786 THR THR A . n 
B 2 787 LEU 787 787 787 LEU LEU A . n 
B 2 788 ILE 788 788 788 ILE ILE A . n 
B 2 789 PHE 789 789 789 PHE PHE A . n 
B 2 790 PHE 790 790 790 PHE PHE A . n 
B 2 791 PRO 791 791 791 PRO PRO A . n 
B 2 792 LEU 792 792 792 LEU LEU A . n 
B 2 793 PRO 793 793 793 PRO PRO A . n 
B 2 794 ALA 794 794 794 ALA ALA A . n 
B 2 795 CYS 795 795 795 CYS CYS A . n 
B 2 796 LEU 796 796 796 LEU LEU A . n 
B 2 797 ASN 797 797 797 ASN ASN A . n 
B 2 798 PRO 798 798 798 PRO PRO A . n 
B 2 799 VAL 799 799 799 VAL VAL A . n 
B 2 800 LEU 800 800 800 LEU LEU A . n 
B 2 801 TYR 801 801 801 TYR TYR A . n 
B 2 802 VAL 802 802 802 VAL VAL A . n 
B 2 803 PHE 803 803 803 PHE PHE A . n 
B 2 804 PHE 804 804 804 PHE PHE A . n 
B 2 805 ASN 805 805 805 ASN ASN A . n 
B 2 806 PRO 806 806 806 PRO PRO A . n 
B 2 807 LYS 807 807 807 LYS LYS A . n 
B 2 808 PHE 808 808 808 PHE PHE A . n 
B 2 809 LYS 809 809 809 LYS LYS A . n 
B 2 810 GLU 810 810 810 GLU GLU A . n 
B 2 811 ASP 811 811 811 ASP ASP A . n 
B 2 812 TRP 812 812 812 TRP TRP A . n 
B 2 813 LYS 813 813 813 LYS LYS A . n 
B 2 814 LEU 814 814 814 LEU LEU A . n 
B 2 815 LEU 815 815 815 LEU LEU A . n 
B 2 816 LYS 816 816 816 LYS LYS A . n 
B 2 817 ARG 817 817 817 ARG ARG A . n 
B 2 818 ARG 818 818 818 ARG ARG A . n 
B 2 819 VAL 819 819 819 VAL VAL A . n 
B 2 820 THR 820 820 820 THR THR A . n 
B 2 821 LYS 821 821 821 LYS LYS A . n 
B 2 822 LYS 822 822 ?   ?   ?   A . n 
B 2 823 SER 823 823 ?   ?   ?   A . n 
B 2 824 GLY 824 824 ?   ?   ?   A . n 
B 2 825 SER 825 825 ?   ?   ?   A . n 
B 2 826 VAL 826 826 ?   ?   ?   A . n 
B 2 827 SER 827 827 ?   ?   ?   A . n 
B 2 828 VAL 828 828 ?   ?   ?   A . n 
B 2 829 SER 829 829 ?   ?   ?   A . n 
B 2 830 ILE 830 830 ?   ?   ?   A . n 
B 2 831 SER 831 831 ?   ?   ?   A . n 
B 2 832 SER 832 832 ?   ?   ?   A . n 
B 2 833 GLN 833 833 ?   ?   ?   A . n 
B 2 834 GLY 834 834 ?   ?   ?   A . n 
B 2 835 GLY 835 835 ?   ?   ?   A . n 
B 2 836 CYS 836 836 ?   ?   ?   A . n 
B 2 837 LEU 837 837 ?   ?   ?   A . n 
B 2 838 GLU 838 838 ?   ?   ?   A . n 
B 2 839 GLN 839 839 ?   ?   ?   A . n 
B 2 840 ASP 840 840 ?   ?   ?   A . n 
B 2 841 PHE 841 841 ?   ?   ?   A . n 
B 2 842 TYR 842 842 ?   ?   ?   A . n 
B 2 843 TYR 843 843 ?   ?   ?   A . n 
B 2 844 ASP 844 844 ?   ?   ?   A . n 
B 2 845 CYS 845 845 ?   ?   ?   A . n 
B 2 846 GLY 846 846 ?   ?   ?   A . n 
B 2 847 MET 847 847 ?   ?   ?   A . n 
B 2 848 TYR 848 848 ?   ?   ?   A . n 
B 2 849 SER 849 849 ?   ?   ?   A . n 
B 2 850 HIS 850 850 ?   ?   ?   A . n 
B 2 851 LEU 851 851 ?   ?   ?   A . n 
B 2 852 GLN 852 852 ?   ?   ?   A . n 
B 2 853 GLY 853 853 ?   ?   ?   A . n 
B 2 854 ASN 854 854 ?   ?   ?   A . n 
B 2 855 LEU 855 855 ?   ?   ?   A . n 
B 2 856 THR 856 856 ?   ?   ?   A . n 
B 2 857 VAL 857 857 ?   ?   ?   A . n 
B 2 858 CYS 858 858 ?   ?   ?   A . n 
B 2 859 ASP 859 859 ?   ?   ?   A . n 
B 2 860 CYS 860 860 ?   ?   ?   A . n 
B 2 861 CYS 861 861 ?   ?   ?   A . n 
B 2 862 GLU 862 862 ?   ?   ?   A . n 
B 2 863 SER 863 863 ?   ?   ?   A . n 
B 2 864 PHE 864 864 ?   ?   ?   A . n 
B 2 865 LEU 865 865 ?   ?   ?   A . n 
B 2 866 LEU 866 866 ?   ?   ?   A . n 
B 2 867 THR 867 867 ?   ?   ?   A . n 
B 2 868 LYS 868 868 ?   ?   ?   A . n 
B 2 869 PRO 869 869 ?   ?   ?   A . n 
B 2 870 VAL 870 870 ?   ?   ?   A . n 
B 2 871 SER 871 871 ?   ?   ?   A . n 
B 2 872 CYS 872 872 ?   ?   ?   A . n 
B 2 873 LYS 873 873 ?   ?   ?   A . n 
B 2 874 HIS 874 874 ?   ?   ?   A . n 
B 2 875 LEU 875 875 ?   ?   ?   A . n 
B 2 876 ILE 876 876 ?   ?   ?   A . n 
B 2 877 LYS 877 877 ?   ?   ?   A . n 
B 2 878 SER 878 878 ?   ?   ?   A . n 
B 2 879 HIS 879 879 ?   ?   ?   A . n 
B 2 880 SER 880 880 ?   ?   ?   A . n 
B 2 881 CYS 881 881 ?   ?   ?   A . n 
B 2 882 PRO 882 882 ?   ?   ?   A . n 
B 2 883 ALA 883 883 ?   ?   ?   A . n 
B 2 884 LEU 884 884 ?   ?   ?   A . n 
B 2 885 ALA 885 885 ?   ?   ?   A . n 
B 2 886 VAL 886 886 ?   ?   ?   A . n 
B 2 887 ALA 887 887 ?   ?   ?   A . n 
B 2 888 SER 888 888 ?   ?   ?   A . n 
B 2 889 CYS 889 889 ?   ?   ?   A . n 
B 2 890 GLN 890 890 ?   ?   ?   A . n 
B 2 891 ARG 891 891 ?   ?   ?   A . n 
B 2 892 PRO 892 892 ?   ?   ?   A . n 
B 2 893 GLU 893 893 ?   ?   ?   A . n 
B 2 894 GLY 894 894 ?   ?   ?   A . n 
B 2 895 TYR 895 895 ?   ?   ?   A . n 
B 2 896 TRP 896 896 ?   ?   ?   A . n 
B 2 897 SER 897 897 ?   ?   ?   A . n 
B 2 898 ASP 898 898 ?   ?   ?   A . n 
B 2 899 CYS 899 899 ?   ?   ?   A . n 
B 2 900 GLY 900 900 ?   ?   ?   A . n 
B 2 901 THR 901 901 ?   ?   ?   A . n 
B 2 902 GLN 902 902 ?   ?   ?   A . n 
B 2 903 SER 903 903 ?   ?   ?   A . n 
B 2 904 ALA 904 904 ?   ?   ?   A . n 
B 2 905 HIS 905 905 ?   ?   ?   A . n 
B 2 906 SER 906 906 ?   ?   ?   A . n 
B 2 907 ASP 907 907 ?   ?   ?   A . n 
B 2 908 TYR 908 908 ?   ?   ?   A . n 
B 2 909 ALA 909 909 ?   ?   ?   A . n 
B 2 910 ASP 910 910 ?   ?   ?   A . n 
B 2 911 GLU 911 911 ?   ?   ?   A . n 
B 2 912 GLU 912 912 ?   ?   ?   A . n 
B 2 913 ASP 913 913 ?   ?   ?   A . n 
B 2 914 SER 914 914 ?   ?   ?   A . n 
B 2 915 PHE 915 915 ?   ?   ?   A . n 
B 2 916 VAL 916 916 ?   ?   ?   A . n 
B 2 917 SER 917 917 ?   ?   ?   A . n 
B 2 918 ASP 918 918 ?   ?   ?   A . n 
B 2 919 SER 919 919 ?   ?   ?   A . n 
B 2 920 SER 920 920 ?   ?   ?   A . n 
B 2 921 ASP 921 921 ?   ?   ?   A . n 
B 2 922 GLN 922 922 ?   ?   ?   A . n 
B 2 923 VAL 923 923 ?   ?   ?   A . n 
B 2 924 GLN 924 924 ?   ?   ?   A . n 
B 2 925 ALA 925 925 ?   ?   ?   A . n 
B 2 926 CYS 926 926 ?   ?   ?   A . n 
B 2 927 GLY 927 927 ?   ?   ?   A . n 
B 2 928 ARG 928 928 ?   ?   ?   A . n 
B 2 929 ALA 929 929 ?   ?   ?   A . n 
B 2 930 CYS 930 930 ?   ?   ?   A . n 
B 2 931 PHE 931 931 ?   ?   ?   A . n 
B 2 932 TYR 932 932 ?   ?   ?   A . n 
B 2 933 GLN 933 933 ?   ?   ?   A . n 
B 2 934 SER 934 934 ?   ?   ?   A . n 
B 2 935 ARG 935 935 ?   ?   ?   A . n 
B 2 936 GLY 936 936 ?   ?   ?   A . n 
B 2 937 PHE 937 937 ?   ?   ?   A . n 
B 2 938 PRO 938 938 ?   ?   ?   A . n 
B 2 939 LEU 939 939 ?   ?   ?   A . n 
B 2 940 VAL 940 940 ?   ?   ?   A . n 
B 2 941 ARG 941 941 ?   ?   ?   A . n 
B 2 942 TYR 942 942 ?   ?   ?   A . n 
B 2 943 ALA 943 943 ?   ?   ?   A . n 
B 2 944 TYR 944 944 ?   ?   ?   A . n 
B 2 945 ASN 945 945 ?   ?   ?   A . n 
B 2 946 LEU 946 946 ?   ?   ?   A . n 
B 2 947 PRO 947 947 ?   ?   ?   A . n 
B 2 948 ARG 948 948 ?   ?   ?   A . n 
B 2 949 VAL 949 949 ?   ?   ?   A . n 
B 2 950 LYS 950 950 ?   ?   ?   A . n 
B 2 951 ASP 951 951 ?   ?   ?   A . n 
C 3 1   MET 1   1   ?   ?   ?   B . n 
C 3 2   GLN 2   2   ?   ?   ?   B . n 
C 3 3   PHE 3   3   ?   ?   ?   B . n 
C 3 4   ARG 4   4   ?   ?   ?   B . n 
C 3 5   LEU 5   5   ?   ?   ?   B . n 
C 3 6   PHE 6   6   ?   ?   ?   B . n 
C 3 7   SER 7   7   ?   ?   ?   B . n 
C 3 8   PHE 8   8   ?   ?   ?   B . n 
C 3 9   ALA 9   9   ?   ?   ?   B . n 
C 3 10  LEU 10  10  ?   ?   ?   B . n 
C 3 11  ILE 11  11  ?   ?   ?   B . n 
C 3 12  ILE 12  12  ?   ?   ?   B . n 
C 3 13  LEU 13  13  ?   ?   ?   B . n 
C 3 14  ASN 14  14  ?   ?   ?   B . n 
C 3 15  CYS 15  15  ?   ?   ?   B . n 
C 3 16  MET 16  16  ?   ?   ?   B . n 
C 3 17  ASP 17  17  ?   ?   ?   B . n 
C 3 18  TYR 18  18  ?   ?   ?   B . n 
C 3 19  SER 19  19  ?   ?   ?   B . n 
C 3 20  HIS 20  20  ?   ?   ?   B . n 
C 3 21  CYS 21  21  ?   ?   ?   B . n 
C 3 22  GLN 22  22  ?   ?   ?   B . n 
C 3 23  GLY 23  23  ?   ?   ?   B . n 
C 3 24  ASN 24  24  ?   ?   ?   B . n 
C 3 25  ARG 25  25  ?   ?   ?   B . n 
C 3 26  TRP 26  26  ?   ?   ?   B . n 
C 3 27  ARG 27  27  ?   ?   ?   B . n 
C 3 28  ARG 28  28  ?   ?   ?   B . n 
C 3 29  SER 29  29  ?   ?   ?   B . n 
C 3 30  LYS 30  30  ?   ?   ?   B . n 
C 3 31  ARG 31  31  ?   ?   ?   B . n 
C 3 32  ALA 32  32  ?   ?   ?   B . n 
C 3 33  SER 33  33  ?   ?   ?   B . n 
C 3 34  TYR 34  34  ?   ?   ?   B . n 
C 3 35  VAL 35  35  ?   ?   ?   B . n 
C 3 36  SER 36  36  ?   ?   ?   B . n 
C 3 37  ASN 37  37  ?   ?   ?   B . n 
C 3 38  PRO 38  38  ?   ?   ?   B . n 
C 3 39  ILE 39  39  39  ILE ILE B . n 
C 3 40  CYS 40  40  40  CYS CYS B . n 
C 3 41  LYS 41  41  41  LYS LYS B . n 
C 3 42  GLY 42  42  42  GLY GLY B . n 
C 3 43  CYS 43  43  43  CYS CYS B . n 
C 3 44  LEU 44  44  44  LEU LEU B . n 
C 3 45  SER 45  45  45  SER SER B . n 
C 3 46  CYS 46  46  46  CYS CYS B . n 
C 3 47  SER 47  47  47  SER SER B . n 
C 3 48  LYS 48  48  48  LYS LYS B . n 
C 3 49  ASP 49  49  49  ASP ASP B . n 
C 3 50  ASN 50  50  50  ASN ASN B . n 
C 3 51  GLY 51  51  51  GLY GLY B . n 
C 3 52  CYS 52  52  52  CYS CYS B . n 
C 3 53  SER 53  53  53  SER SER B . n 
C 3 54  ARG 54  54  54  ARG ARG B . n 
C 3 55  CYS 55  55  55  CYS CYS B . n 
C 3 56  GLN 56  56  56  GLN GLN B . n 
C 3 57  GLN 57  57  57  GLN GLN B . n 
C 3 58  LYS 58  58  58  LYS LYS B . n 
C 3 59  LEU 59  59  59  LEU LEU B . n 
C 3 60  PHE 60  60  60  PHE PHE B . n 
C 3 61  PHE 61  61  61  PHE PHE B . n 
C 3 62  PHE 62  62  62  PHE PHE B . n 
C 3 63  LEU 63  63  63  LEU LEU B . n 
C 3 64  ARG 64  64  64  ARG ARG B . n 
C 3 65  ARG 65  65  65  ARG ARG B . n 
C 3 66  GLU 66  66  66  GLU GLU B . n 
C 3 67  GLY 67  67  67  GLY GLY B . n 
C 3 68  MET 68  68  68  MET MET B . n 
C 3 69  ARG 69  69  69  ARG ARG B . n 
C 3 70  GLN 70  70  70  GLN GLN B . n 
C 3 71  TYR 71  71  71  TYR TYR B . n 
C 3 72  GLY 72  72  72  GLY GLY B . n 
C 3 73  GLU 73  73  73  GLU GLU B . n 
C 3 74  CYS 74  74  74  CYS CYS B . n 
C 3 75  LEU 75  75  75  LEU LEU B . n 
C 3 76  HIS 76  76  76  HIS HIS B . n 
C 3 77  SER 77  77  77  SER SER B . n 
C 3 78  CYS 78  78  78  CYS CYS B . n 
C 3 79  PRO 79  79  79  PRO PRO B . n 
C 3 80  SER 80  80  80  SER SER B . n 
C 3 81  GLY 81  81  81  GLY GLY B . n 
C 3 82  TYR 82  82  82  TYR TYR B . n 
C 3 83  TYR 83  83  83  TYR TYR B . n 
C 3 84  GLY 84  84  84  GLY GLY B . n 
C 3 85  HIS 85  85  85  HIS HIS B . n 
C 3 86  ARG 86  86  86  ARG ARG B . n 
C 3 87  ALA 87  87  87  ALA ALA B . n 
C 3 88  PRO 88  88  88  PRO PRO B . n 
C 3 89  ASP 89  89  89  ASP ASP B . n 
C 3 90  MET 90  90  90  MET MET B . n 
C 3 91  ASN 91  91  91  ASN ASN B . n 
C 3 92  ARG 92  92  92  ARG ARG B . n 
C 3 93  CYS 93  93  93  CYS CYS B . n 
C 3 94  ALA 94  94  94  ALA ALA B . n 
C 3 95  ARG 95  95  95  ARG ARG B . n 
C 3 96  CYS 96  96  96  CYS CYS B . n 
C 3 97  ARG 97  97  97  ARG ARG B . n 
C 3 98  ILE 98  98  98  ILE ILE B . n 
C 3 99  GLU 99  99  99  GLU GLU B . n 
C 3 100 ASN 100 100 100 ASN ASN B . n 
C 3 101 CYS 101 101 101 CYS CYS B . n 
C 3 102 ASP 102 102 102 ASP ASP B . n 
C 3 103 SER 103 103 103 SER SER B . n 
C 3 104 CYS 104 104 104 CYS CYS B . n 
C 3 105 PHE 105 105 105 PHE PHE B . n 
C 3 106 SER 106 106 106 SER SER B . n 
C 3 107 LYS 107 107 107 LYS LYS B . n 
C 3 108 ASP 108 108 108 ASP ASP B . n 
C 3 109 PHE 109 109 109 PHE PHE B . n 
C 3 110 CYS 110 110 110 CYS CYS B . n 
C 3 111 THR 111 111 111 THR THR B . n 
C 3 112 LYS 112 112 112 LYS LYS B . n 
C 3 113 CYS 113 113 113 CYS CYS B . n 
C 3 114 LYS 114 114 114 LYS LYS B . n 
C 3 115 VAL 115 115 115 VAL VAL B . n 
C 3 116 GLY 116 116 116 GLY GLY B . n 
C 3 117 PHE 117 117 117 PHE PHE B . n 
C 3 118 TYR 118 118 118 TYR TYR B . n 
C 3 119 LEU 119 119 119 LEU LEU B . n 
C 3 120 HIS 120 120 120 HIS HIS B . n 
C 3 121 ARG 121 121 121 ARG ARG B . n 
C 3 122 GLY 122 122 122 GLY GLY B . n 
C 3 123 ARG 123 123 123 ARG ARG B . n 
C 3 124 CYS 124 124 124 CYS CYS B . n 
C 3 125 PHE 125 125 125 PHE PHE B . n 
C 3 126 ASP 126 126 126 ASP ASP B . n 
C 3 127 GLU 127 127 127 GLU GLU B . n 
C 3 128 CYS 128 128 128 CYS CYS B . n 
C 3 129 PRO 129 129 129 PRO PRO B . n 
C 3 130 ASP 130 130 130 ASP ASP B . n 
C 3 131 GLY 131 131 131 GLY GLY B . n 
C 3 132 PHE 132 132 132 PHE PHE B . n 
C 3 133 ALA 133 133 133 ALA ALA B . n 
C 3 134 PRO 134 134 134 PRO PRO B . n 
C 3 135 LEU 135 135 135 LEU LEU B . n 
C 3 136 ASP 136 136 136 ASP ASP B . n 
C 3 137 GLU 137 137 137 GLU GLU B . n 
C 3 138 THR 138 138 138 THR THR B . n 
C 3 139 MET 139 139 139 MET MET B . n 
C 3 140 GLU 140 140 140 GLU GLU B . n 
C 3 141 CYS 141 141 141 CYS CYS B . n 
C 3 142 VAL 142 142 ?   ?   ?   B . n 
C 3 143 GLU 143 143 ?   ?   ?   B . n 
C 3 144 GLY 144 144 ?   ?   ?   B . n 
C 3 145 CYS 145 145 ?   ?   ?   B . n 
C 3 146 GLU 146 146 ?   ?   ?   B . n 
C 3 147 VAL 147 147 ?   ?   ?   B . n 
C 3 148 GLY 148 148 ?   ?   ?   B . n 
C 3 149 HIS 149 149 ?   ?   ?   B . n 
C 3 150 TRP 150 150 ?   ?   ?   B . n 
C 3 151 SER 151 151 ?   ?   ?   B . n 
C 3 152 GLU 152 152 ?   ?   ?   B . n 
C 3 153 TRP 153 153 ?   ?   ?   B . n 
C 3 154 GLY 154 154 ?   ?   ?   B . n 
C 3 155 THR 155 155 ?   ?   ?   B . n 
C 3 156 CYS 156 156 ?   ?   ?   B . n 
C 3 157 SER 157 157 ?   ?   ?   B . n 
C 3 158 ARG 158 158 ?   ?   ?   B . n 
C 3 159 ASN 159 159 ?   ?   ?   B . n 
C 3 160 ASN 160 160 ?   ?   ?   B . n 
C 3 161 ARG 161 161 ?   ?   ?   B . n 
C 3 162 THR 162 162 ?   ?   ?   B . n 
C 3 163 CYS 163 163 ?   ?   ?   B . n 
C 3 164 GLY 164 164 ?   ?   ?   B . n 
C 3 165 PHE 165 165 ?   ?   ?   B . n 
C 3 166 LYS 166 166 ?   ?   ?   B . n 
C 3 167 TRP 167 167 ?   ?   ?   B . n 
C 3 168 GLY 168 168 ?   ?   ?   B . n 
C 3 169 LEU 169 169 ?   ?   ?   B . n 
C 3 170 GLU 170 170 ?   ?   ?   B . n 
C 3 171 THR 171 171 ?   ?   ?   B . n 
C 3 172 ARG 172 172 ?   ?   ?   B . n 
C 3 173 THR 173 173 ?   ?   ?   B . n 
C 3 174 ARG 174 174 ?   ?   ?   B . n 
C 3 175 GLN 175 175 ?   ?   ?   B . n 
C 3 176 ILE 176 176 ?   ?   ?   B . n 
C 3 177 VAL 177 177 ?   ?   ?   B . n 
C 3 178 LYS 178 178 ?   ?   ?   B . n 
C 3 179 LYS 179 179 ?   ?   ?   B . n 
C 3 180 PRO 180 180 ?   ?   ?   B . n 
C 3 181 VAL 181 181 ?   ?   ?   B . n 
C 3 182 LYS 182 182 ?   ?   ?   B . n 
C 3 183 ASP 183 183 ?   ?   ?   B . n 
C 3 184 THR 184 184 ?   ?   ?   B . n 
C 3 185 ILE 185 185 ?   ?   ?   B . n 
C 3 186 LEU 186 186 ?   ?   ?   B . n 
C 3 187 CYS 187 187 ?   ?   ?   B . n 
C 3 188 PRO 188 188 ?   ?   ?   B . n 
C 3 189 THR 189 189 ?   ?   ?   B . n 
C 3 190 ILE 190 190 ?   ?   ?   B . n 
C 3 191 ALA 191 191 ?   ?   ?   B . n 
C 3 192 GLU 192 192 ?   ?   ?   B . n 
C 3 193 SER 193 193 ?   ?   ?   B . n 
C 3 194 ARG 194 194 ?   ?   ?   B . n 
C 3 195 ARG 195 195 ?   ?   ?   B . n 
C 3 196 CYS 196 196 ?   ?   ?   B . n 
C 3 197 LYS 197 197 ?   ?   ?   B . n 
C 3 198 MET 198 198 ?   ?   ?   B . n 
C 3 199 THR 199 199 ?   ?   ?   B . n 
C 3 200 MET 200 200 ?   ?   ?   B . n 
C 3 201 ARG 201 201 ?   ?   ?   B . n 
C 3 202 HIS 202 202 ?   ?   ?   B . n 
C 3 203 CYS 203 203 ?   ?   ?   B . n 
C 3 204 PRO 204 204 ?   ?   ?   B . n 
C 3 205 GLY 205 205 ?   ?   ?   B . n 
C 3 206 GLY 206 206 ?   ?   ?   B . n 
C 3 207 LYS 207 207 ?   ?   ?   B . n 
C 3 208 ARG 208 208 ?   ?   ?   B . n 
C 3 209 THR 209 209 ?   ?   ?   B . n 
C 3 210 PRO 210 210 ?   ?   ?   B . n 
C 3 211 LYS 211 211 ?   ?   ?   B . n 
C 3 212 ALA 212 212 ?   ?   ?   B . n 
C 3 213 LYS 213 213 ?   ?   ?   B . n 
C 3 214 GLU 214 214 ?   ?   ?   B . n 
C 3 215 LYS 215 215 ?   ?   ?   B . n 
C 3 216 ARG 216 216 ?   ?   ?   B . n 
C 3 217 ASN 217 217 ?   ?   ?   B . n 
C 3 218 LYS 218 218 ?   ?   ?   B . n 
C 3 219 LYS 219 219 ?   ?   ?   B . n 
C 3 220 LYS 220 220 ?   ?   ?   B . n 
C 3 221 LYS 221 221 ?   ?   ?   B . n 
C 3 222 ARG 222 222 ?   ?   ?   B . n 
C 3 223 LYS 223 223 ?   ?   ?   B . n 
C 3 224 LEU 224 224 ?   ?   ?   B . n 
C 3 225 ILE 225 225 ?   ?   ?   B . n 
C 3 226 GLU 226 226 ?   ?   ?   B . n 
C 3 227 ARG 227 227 ?   ?   ?   B . n 
C 3 228 ALA 228 228 ?   ?   ?   B . n 
C 3 229 GLN 229 229 ?   ?   ?   B . n 
C 3 230 GLU 230 230 ?   ?   ?   B . n 
C 3 231 GLN 231 231 ?   ?   ?   B . n 
C 3 232 HIS 232 232 ?   ?   ?   B . n 
C 3 233 SER 233 233 ?   ?   ?   B . n 
C 3 234 VAL 234 234 ?   ?   ?   B . n 
C 3 235 PHE 235 235 ?   ?   ?   B . n 
C 3 236 LEU 236 236 ?   ?   ?   B . n 
C 3 237 ALA 237 237 ?   ?   ?   B . n 
C 3 238 THR 238 238 ?   ?   ?   B . n 
C 3 239 ASP 239 239 ?   ?   ?   B . n 
C 3 240 ARG 240 240 ?   ?   ?   B . n 
C 3 241 ALA 241 241 ?   ?   ?   B . n 
C 3 242 ASN 242 242 ?   ?   ?   B . n 
C 3 243 GLN 243 243 ?   ?   ?   B . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 C ASN 498 ? CG  ? A ASN 58  CG  
2  1 Y 1 C ASN 498 ? OD1 ? A ASN 58  OD1 
3  1 Y 1 C ASN 498 ? ND2 ? A ASN 58  ND2 
4  1 Y 1 C LYS 500 ? CG  ? A LYS 60  CG  
5  1 Y 1 C LYS 500 ? CD  ? A LYS 60  CD  
6  1 Y 1 C LYS 500 ? CE  ? A LYS 60  CE  
7  1 Y 1 C LYS 500 ? NZ  ? A LYS 60  NZ  
8  1 Y 1 A LYS 79  ? CG  ? B LYS 78  CG  
9  1 Y 1 A LYS 79  ? CD  ? B LYS 78  CD  
10 1 Y 1 A LYS 79  ? CE  ? B LYS 78  CE  
11 1 Y 1 A LYS 79  ? NZ  ? B LYS 78  NZ  
12 1 Y 1 A TRP 475 ? CG  ? B TRP 474 CG  
13 1 Y 1 A TRP 475 ? CD1 ? B TRP 474 CD1 
14 1 Y 1 A TRP 475 ? CD2 ? B TRP 474 CD2 
15 1 Y 1 A TRP 475 ? NE1 ? B TRP 474 NE1 
16 1 Y 1 A TRP 475 ? CE2 ? B TRP 474 CE2 
17 1 Y 1 A TRP 475 ? CE3 ? B TRP 474 CE3 
18 1 Y 1 A TRP 475 ? CZ2 ? B TRP 474 CZ2 
19 1 Y 1 A TRP 475 ? CZ3 ? B TRP 474 CZ3 
20 1 Y 1 A TRP 475 ? CH2 ? B TRP 474 CH2 
21 1 Y 1 A CYS 477 ? SG  ? B CYS 476 SG  
22 1 Y 1 A ASP 478 ? CG  ? B ASP 477 CG  
23 1 Y 1 A ASP 478 ? OD1 ? B ASP 477 OD1 
24 1 Y 1 A ASP 478 ? OD2 ? B ASP 477 OD2 
25 1 Y 1 A SER 479 ? OG  ? B SER 478 OG  
26 1 Y 1 A SER 516 ? OG  ? B SER 516 OG  
27 1 Y 1 A GLN 517 ? CG  ? B GLN 517 CG  
28 1 Y 1 A GLN 517 ? CD  ? B GLN 517 CD  
29 1 Y 1 A GLN 517 ? OE1 ? B GLN 517 OE1 
30 1 Y 1 A GLN 517 ? NE2 ? B GLN 517 NE2 
31 1 Y 1 A ILE 518 ? CG1 ? B ILE 518 CG1 
32 1 Y 1 A ILE 518 ? CG2 ? B ILE 518 CG2 
33 1 Y 1 A ILE 518 ? CD1 ? B ILE 518 CD1 
34 1 Y 1 A ILE 519 ? CG1 ? B ILE 519 CG1 
35 1 Y 1 A ILE 519 ? CG2 ? B ILE 519 CG2 
36 1 Y 1 A ILE 519 ? CD1 ? B ILE 519 CD1 
37 1 Y 1 A MET 721 ? CG  ? B MET 721 CG  
38 1 Y 1 A MET 721 ? SD  ? B MET 721 SD  
39 1 Y 1 A MET 721 ? CE  ? B MET 721 CE  
40 1 Y 1 B ILE 39  ? CG1 ? C ILE 39  CG1 
41 1 Y 1 B ILE 39  ? CG2 ? C ILE 39  CG2 
42 1 Y 1 B ILE 39  ? CD1 ? C ILE 39  CD1 
43 1 Y 1 B ARG 54  ? CG  ? C ARG 54  CG  
44 1 Y 1 B ARG 54  ? CD  ? C ARG 54  CD  
45 1 Y 1 B ARG 54  ? NE  ? C ARG 54  NE  
46 1 Y 1 B ARG 54  ? CZ  ? C ARG 54  CZ  
47 1 Y 1 B ARG 54  ? NH1 ? C ARG 54  NH1 
48 1 Y 1 B ARG 54  ? NH2 ? C ARG 54  NH2 
49 1 Y 1 B GLN 57  ? CG  ? C GLN 57  CG  
50 1 Y 1 B GLN 57  ? CD  ? C GLN 57  CD  
51 1 Y 1 B GLN 57  ? OE1 ? C GLN 57  OE1 
52 1 Y 1 B GLN 57  ? NE2 ? C GLN 57  NE2 
53 1 Y 1 B ASP 130 ? CG  ? C ASP 130 CG  
54 1 Y 1 B ASP 130 ? OD1 ? C ASP 130 OD1 
55 1 Y 1 B ASP 130 ? OD2 ? C ASP 130 OD2 
56 1 Y 1 B GLU 137 ? CG  ? C GLU 137 CG  
57 1 Y 1 B GLU 137 ? CD  ? C GLU 137 CD  
58 1 Y 1 B GLU 137 ? OE1 ? C GLU 137 OE1 
59 1 Y 1 B GLU 137 ? OE2 ? C GLU 137 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XUM 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XUM 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XUM 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8XUM 
_struct.title                        'Structure of LGR4 with RSPO2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XUM 
_struct_keywords.text            'LGR4, RSPO2, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8XUM        8XUM   ? 1 ? 1 
2 UNP LGR4_HUMAN  Q9BXB1 ? 2 
;MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDRRVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNF
PFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWL
DDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEF
PQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVH
LESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNL
IHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYA
NLNTEDNSLQDHSVAQEKGTADAANVTSTLENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALFFNLLVI
LTTFASCTSLPSSKLFIGLISVSNLFMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLAT
VERSLSAKDIMKNGKSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLPFPTGETPSLGFTVTLVLLNSLAFLL
MAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAISISPEIMKSVTLIFFPLPACLNPVL
YVFFNPKFKEDWKLLKRRVTKKSGSVSVSISSQGGCLEQDFYYDCGMYSHLQGNLTVCDCCESFLLTKPVSCKHLIKSHS
CPALAVASCQRPEGYWSDCGTQSAHSDYADEEDSFVSDSSDQVQACGRACFYQSRGFPLVRYAYNLPRVKD
;
0 
3 UNP RSPO2_HUMAN Q6UXX9 ? 3 
;MQFRLFSFALIILNCMDYSHCQGNRWRRSKRASYVSNPICKGCLSCSKDNGCSRCQQKLFFFLRREGMRQYGECLHSCPS
GYYGHRAPDMNRCARCRIENCDSCFSKDFCTKCKVGFYLHRGRCFDECPDGFAPLEETMECVEGCEVGHWSEWGTCSRNN
RTCGFKWGLETRTRQIVKKPVKDTILCPTIAESRRCKMTMRHCPGGKRTPKAKEKRNKKKKRKLIERAQEQHSVFLATDR
ANQ
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XUM C 1 ? 110 ? 8XUM   441 ? 550 ? 441 550 
2 2 8XUM A 1 ? 951 ? Q9BXB1 1   ? 951 ? 2   951 
3 3 8XUM B 1 ? 243 ? Q6UXX9 1   ? 243 ? 1   243 
# 
_struct_ref_seq_dif.align_id                     3 
_struct_ref_seq_dif.pdbx_pdb_id_code             8XUM 
_struct_ref_seq_dif.mon_id                       ASP 
_struct_ref_seq_dif.pdbx_pdb_strand_id           B 
_struct_ref_seq_dif.seq_num                      136 
_struct_ref_seq_dif.pdbx_pdb_ins_code            ? 
_struct_ref_seq_dif.pdbx_seq_db_name             UNP 
_struct_ref_seq_dif.pdbx_seq_db_accession_code   Q6UXX9 
_struct_ref_seq_dif.db_mon_id                    GLU 
_struct_ref_seq_dif.pdbx_seq_db_seq_num          136 
_struct_ref_seq_dif.details                      conflict 
_struct_ref_seq_dif.pdbx_auth_seq_num            136 
_struct_ref_seq_dif.pdbx_ordinal                 1 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO B 169 ? LEU B 176 ? PRO A 170 LEU A 177 1 ? 8  
HELX_P HELX_P2  AA2 GLN B 242 ? LEU B 247 ? GLN A 243 LEU A 248 5 ? 6  
HELX_P HELX_P3  AA3 ASN B 337 ? GLN B 342 ? ASN A 338 GLN A 343 1 ? 6  
HELX_P HELX_P4  AA4 CYS B 470 ? GLY B 475 ? CYS A 471 GLY A 476 1 ? 6  
HELX_P HELX_P5  AA5 SER B 538 ? ALA B 565 ? SER A 538 ALA A 565 1 ? 28 
HELX_P HELX_P6  AA6 PRO B 571 ? SER B 601 ? PRO A 571 SER A 601 1 ? 31 
HELX_P HELX_P7  AA7 ARG B 604 ? GLU B 607 ? ARG A 604 GLU A 607 5 ? 4  
HELX_P HELX_P8  AA8 PHE B 608 ? THR B 614 ? PHE A 608 THR A 614 1 ? 7  
HELX_P HELX_P9  AA9 GLY B 615 ? ASP B 649 ? GLY A 615 ASP A 649 1 ? 35 
HELX_P HELX_P10 AB1 HIS B 658 ? HIS B 683 ? HIS A 658 HIS A 683 1 ? 26 
HELX_P HELX_P11 AB2 SER B 703 ? LEU B 732 ? SER A 703 LEU A 732 1 ? 30 
HELX_P HELX_P12 AB3 MET B 745 ? ALA B 769 ? MET A 745 ALA A 769 1 ? 25 
HELX_P HELX_P13 AB4 PRO B 770 ? ILE B 772 ? PRO A 770 ILE A 772 5 ? 3  
HELX_P HELX_P14 AB5 SER B 778 ? PHE B 790 ? SER A 778 PHE A 790 1 ? 13 
HELX_P HELX_P15 AB6 PRO B 791 ? PHE B 804 ? PRO A 791 PHE A 804 1 ? 14 
HELX_P HELX_P16 AB7 ASN B 805 ? LYS B 821 ? ASN A 805 LYS A 821 1 ? 17 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 7   SG ? ? ? 1_555 A CYS 80  SG ? ? C CYS 447 C CYS 520 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf2  disulf ? ? B CYS 33  SG ? ? ? 1_555 B CYS 43  SG ? ? A CYS 34  A CYS 44  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3  disulf ? ? B CYS 618 SG ? ? ? 1_555 B CYS 693 SG ? ? A CYS 618 A CYS 693 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf4  disulf ? ? C CYS 40  SG ? ? ? 1_555 C CYS 46  SG ? ? B CYS 40  B CYS 46  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf5  disulf ? ? C CYS 43  SG ? ? ? 1_555 C CYS 52  SG ? ? B CYS 43  B CYS 52  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf6  disulf ? ? C CYS 55  SG ? ? ? 1_555 C CYS 74  SG ? ? B CYS 55  B CYS 74  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf7  disulf ? ? C CYS 78  SG ? ? ? 1_555 C CYS 93  SG ? ? B CYS 78  B CYS 93  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf8  disulf ? ? C CYS 96  SG ? ? ? 1_555 C CYS 104 SG ? ? B CYS 96  B CYS 104 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf9  disulf ? ? C CYS 101 SG ? ? ? 1_555 C CYS 110 SG ? ? B CYS 101 B CYS 110 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf10 disulf ? ? C CYS 113 SG ? ? ? 1_555 C CYS 124 SG ? ? B CYS 113 B CYS 124 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf11 disulf ? ? C CYS 128 SG ? ? ? 1_555 C CYS 141 SG ? ? B CYS 128 B CYS 141 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 7   ? CYS A 80  ? CYS C 447 ? 1_555 CYS C 520 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2  CYS B 33  ? CYS B 43  ? CYS A 34  ? 1_555 CYS A 44  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS B 618 ? CYS B 693 ? CYS A 618 ? 1_555 CYS A 693 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS C 40  ? CYS C 46  ? CYS B 40  ? 1_555 CYS B 46  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5  CYS C 43  ? CYS C 52  ? CYS B 43  ? 1_555 CYS B 52  ? 1_555 SG SG . . . None 'Disulfide bridge' 
6  CYS C 55  ? CYS C 74  ? CYS B 55  ? 1_555 CYS B 74  ? 1_555 SG SG . . . None 'Disulfide bridge' 
7  CYS C 78  ? CYS C 93  ? CYS B 78  ? 1_555 CYS B 93  ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS C 96  ? CYS C 104 ? CYS B 96  ? 1_555 CYS B 104 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9  CYS C 101 ? CYS C 110 ? CYS B 101 ? 1_555 CYS B 110 ? 1_555 SG SG . . . None 'Disulfide bridge' 
10 CYS C 113 ? CYS C 124 ? CYS B 113 ? 1_555 CYS B 124 ? 1_555 SG SG . . . None 'Disulfide bridge' 
11 CYS C 128 ? CYS C 141 ? CYS B 128 ? 1_555 CYS B 141 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3  ? 
AA2 ? 5  ? 
AA3 ? 5  ? 
AA4 ? 12 ? 
AA5 ? 2  ? 
AA6 ? 2  ? 
AA7 ? 2  ? 
AA8 ? 2  ? 
AA9 ? 7  ? 
AB1 ? 2  ? 
AB2 ? 4  ? 
AB3 ? 2  ? 
AB4 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA2 4  5  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA4 2  3  ? parallel      
AA4 3  4  ? parallel      
AA4 4  5  ? parallel      
AA4 5  6  ? parallel      
AA4 6  7  ? parallel      
AA4 7  8  ? parallel      
AA4 8  9  ? parallel      
AA4 9  10 ? parallel      
AA4 10 11 ? parallel      
AA4 11 12 ? parallel      
AA5 1  2  ? parallel      
AA6 1  2  ? parallel      
AA7 1  2  ? parallel      
AA8 1  2  ? parallel      
AA9 1  2  ? parallel      
AA9 2  3  ? parallel      
AA9 3  4  ? parallel      
AA9 4  5  ? parallel      
AA9 5  6  ? parallel      
AA9 6  7  ? parallel      
AB1 1  2  ? anti-parallel 
AB2 1  2  ? anti-parallel 
AB2 2  3  ? parallel      
AB2 3  4  ? anti-parallel 
AB3 1  2  ? anti-parallel 
AB4 1  2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  SER A 2   ? ALA A 8   ? SER C 442 ALA C 448 
AA1 2  THR A 62  ? ASN A 68  ? THR C 502 ASN C 508 
AA1 3  PHE A 52  ? SER A 55  ? PHE C 492 SER C 495 
AA2 1  THR A 42  ? TYR A 44  ? THR C 482 TYR C 484 
AA2 2  ARG A 30  ? VAL A 36  ? ARG C 470 VAL C 476 
AA2 3  MET A 19  ? GLN A 24  ? MET C 459 GLN C 464 
AA2 4  MET A 77  ? SER A 82  ? MET C 517 SER C 522 
AA2 5  TYR A 99  ? TRP A 100 ? TYR C 539 TRP C 540 
AA3 1  THR A 42  ? TYR A 44  ? THR C 482 TYR C 484 
AA3 2  ARG A 30  ? VAL A 36  ? ARG C 470 VAL C 476 
AA3 3  MET A 19  ? GLN A 24  ? MET C 459 GLN C 464 
AA3 4  MET A 77  ? SER A 82  ? MET C 517 SER C 522 
AA3 5  THR A 104 ? GLN A 105 ? THR C 544 GLN C 545 
AA4 1  SER B 34  ? CYS B 35  ? SER A 35  CYS A 36  
AA4 2  ARG B 40  ? ASP B 42  ? ARG A 41  ASP A 43  
AA4 3  ALA B 61  ? ASP B 63  ? ALA A 62  ASP A 64  
AA4 4  GLU B 85  ? GLN B 87  ? GLU A 86  GLN A 88  
AA4 5  VAL B 109 ? THR B 111 ? VAL A 110 THR A 112 
AA4 6  SER B 133 ? ARG B 135 ? SER A 134 ARG A 136 
AA4 7  HIS B 157 ? TRP B 159 ? HIS A 158 TRP A 160 
AA4 8  ALA B 181 ? THR B 183 ? ALA A 182 THR A 184 
AA4 9  VAL B 205 ? HIS B 207 ? VAL A 206 HIS A 208 
AA4 10 THR B 229 ? ASP B 231 ? THR A 230 ASP A 232 
AA4 11 GLU B 252 ? GLY B 254 ? GLU A 253 GLY A 255 
AA4 12 THR B 276 ? HIS B 278 ? THR A 277 HIS A 279 
AA5 1  GLN B 71  ? LEU B 72  ? GLN A 72  LEU A 73  
AA5 2  PHE B 95  ? ILE B 96  ? PHE A 96  ILE A 97  
AA6 1  SER B 191 ? ILE B 192 ? SER A 192 ILE A 193 
AA6 2  SER B 215 ? LEU B 216 ? SER A 216 LEU A 217 
AA7 1  VAL B 262 ? ILE B 263 ? VAL A 263 ILE A 264 
AA7 2  PHE B 286 ? VAL B 287 ? PHE A 287 VAL A 288 
AA8 1  VAL B 302 ? ARG B 304 ? VAL A 303 ARG A 305 
AA8 2  THR B 325 ? THR B 327 ? THR A 326 THR A 328 
AA9 1  THR B 347 ? ASP B 349 ? THR A 348 ASP A 350 
AA9 2  GLU B 369 ? SER B 371 ? GLU A 370 SER A 372 
AA9 3  ILE B 393 ? ASP B 395 ? ILE A 394 ASP A 396 
AA9 4  ASN B 417 ? ASP B 419 ? ASN A 418 ASP A 420 
AA9 5  GLN B 438 ? LYS B 440 ? GLN A 439 LYS A 441 
AA9 6  SER B 461 ? SER B 463 ? SER A 462 SER A 464 
AA9 7  HIS B 521 ? CYS B 522 ? HIS A 521 CYS A 522 
AB1 1  CYS C 43  ? SER C 47  ? CYS B 43  SER B 47  
AB1 2  GLY C 51  ? CYS C 55  ? GLY B 51  CYS B 55  
AB2 1  ARG C 69  ? LEU C 75  ? ARG B 69  LEU B 75  
AB2 2  PHE C 60  ? GLU C 66  ? PHE B 60  GLU B 66  
AB2 3  ASN C 91  ? ARG C 95  ? ASN B 91  ARG B 95  
AB2 4  TYR C 82  ? HIS C 85  ? TYR B 82  HIS B 85  
AB3 1  CYS C 101 ? SER C 103 ? CYS B 101 SER B 103 
AB3 2  LYS C 112 ? CYS C 113 ? LYS B 112 CYS B 113 
AB4 1  TYR C 118 ? HIS C 120 ? TYR B 118 HIS B 120 
AB4 2  ARG C 123 ? PHE C 125 ? ARG B 123 PHE B 125 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N CYS A 7   ? N CYS C 447 O LEU A 63  ? O LEU C 503 
AA1 2  3  O GLN A 66  ? O GLN C 506 N THR A 53  ? N THR C 493 
AA2 1  2  O ILE A 43  ? O ILE C 483 N THR A 35  ? N THR C 475 
AA2 2  3  O GLU A 31  ? O GLU C 471 N ARG A 23  ? N ARG C 463 
AA2 3  4  N GLY A 20  ? N GLY C 460 O ALA A 81  ? O ALA C 521 
AA2 4  5  N SER A 82  ? N SER C 522 O TYR A 99  ? O TYR C 539 
AA3 1  2  O ILE A 43  ? O ILE C 483 N THR A 35  ? N THR C 475 
AA3 2  3  O GLU A 31  ? O GLU C 471 N ARG A 23  ? N ARG C 463 
AA3 3  4  N GLY A 20  ? N GLY C 460 O ALA A 81  ? O ALA C 521 
AA3 4  5  N TYR A 78  ? N TYR C 518 O THR A 104 ? O THR C 544 
AA4 1  2  N SER B 34  ? N SER A 35  O ASP B 42  ? O ASP A 43  
AA4 2  3  N VAL B 41  ? N VAL A 42  O ALA B 61  ? O ALA A 62  
AA4 3  4  N LEU B 62  ? N LEU A 63  O GLU B 85  ? O GLU A 86  
AA4 4  5  N LEU B 86  ? N LEU A 87  O VAL B 109 ? O VAL A 110 
AA4 5  6  N LEU B 110 ? N LEU A 111 O SER B 133 ? O SER A 134 
AA4 6  7  N LEU B 134 ? N LEU A 135 O HIS B 157 ? O HIS A 158 
AA4 7  8  N LEU B 158 ? N LEU A 159 O ALA B 181 ? O ALA A 182 
AA4 8  9  N LEU B 182 ? N LEU A 183 O VAL B 205 ? O VAL A 206 
AA4 9  10 N LEU B 206 ? N LEU A 207 O THR B 229 ? O THR A 230 
AA4 10 11 N LEU B 230 ? N LEU A 231 O GLU B 252 ? O GLU A 253 
AA4 11 12 N LEU B 253 ? N LEU A 254 O THR B 276 ? O THR A 277 
AA5 1  2  N LEU B 72  ? N LEU A 73  O PHE B 95  ? O PHE A 96  
AA6 1  2  N ILE B 192 ? N ILE A 193 O SER B 215 ? O SER A 216 
AA7 1  2  N ILE B 263 ? N ILE A 264 O PHE B 286 ? O PHE A 287 
AA8 1  2  N ILE B 303 ? N ILE A 304 O THR B 325 ? O THR A 326 
AA9 1  2  N LEU B 348 ? N LEU A 349 O SER B 371 ? O SER A 372 
AA9 2  3  N ILE B 370 ? N ILE A 371 O ASP B 395 ? O ASP A 396 
AA9 3  4  N LEU B 394 ? N LEU A 395 O ASN B 417 ? O ASN A 418 
AA9 4  5  N LEU B 418 ? N LEU A 419 O GLN B 438 ? O GLN A 439 
AA9 5  6  N LEU B 439 ? N LEU A 440 O SER B 461 ? O SER A 462 
AA9 6  7  N LEU B 462 ? N LEU A 463 O HIS B 521 ? O HIS A 521 
AB1 1  2  N SER C 45  ? N SER B 45  O SER C 53  ? O SER B 53  
AB2 1  2  O GLU C 73  ? O GLU B 73  N PHE C 62  ? N PHE B 62  
AB2 2  3  N PHE C 61  ? N PHE B 61  O ASN C 91  ? O ASN B 91  
AB2 3  4  O ARG C 92  ? O ARG B 92  N HIS C 85  ? N HIS B 85  
AB3 1  2  N ASP C 102 ? N ASP B 102 O LYS C 112 ? O LYS B 112 
AB4 1  2  N HIS C 120 ? N HIS B 120 O ARG C 123 ? O ARG B 123 
# 
_pdbx_entry_details.entry_id                   8XUM 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CD 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            PRO 
_pdbx_validate_rmsd_bond.auth_seq_id_1             798 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            ? 
_pdbx_validate_rmsd_bond.auth_atom_id_2            N 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            PRO 
_pdbx_validate_rmsd_bond.auth_seq_id_2             798 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            ? 
_pdbx_validate_rmsd_bond.bond_value                1.375 
_pdbx_validate_rmsd_bond.bond_target_value         1.474 
_pdbx_validate_rmsd_bond.bond_deviation            -0.099 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.014 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 N  C ASN 501 ? ? CA C ASN 501 ? ? CB C ASN 501 ? ? 99.39  110.60 -11.21 1.80 N 
2 1 N  C ALA 526 ? ? CA C ALA 526 ? ? CB C ALA 526 ? ? 100.78 110.10 -9.32  1.40 N 
3 1 CB A ASN 115 ? ? CA A ASN 115 ? ? C  A ASN 115 ? ? 123.12 110.40 12.72  2.00 N 
4 1 N  B PHE 60  ? ? CA B PHE 60  ? ? CB B PHE 60  ? ? 121.83 110.60 11.23  1.80 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP C 479 ? ? 93.40   7.73    
2  1 SER C 487 ? ? -96.74  32.83   
3  1 ASN C 501 ? ? 19.60   60.04   
4  1 ASP C 514 ? ? -87.12  37.67   
5  1 ALA C 526 ? ? 52.74   -159.40 
6  1 VAL C 528 ? ? 49.30   -172.49 
7  1 MET A 67  ? ? 64.62   -4.06   
8  1 ASN A 115 ? ? 69.17   -10.24  
9  1 ASN A 116 ? ? -68.03  -178.17 
10 1 GLU A 124 ? ? -89.92  37.92   
11 1 LEU A 161 ? ? -144.94 15.23   
12 1 LEU A 209 ? ? -141.03 21.06   
13 1 ASP A 282 ? ? 57.27   17.60   
14 1 GLN A 343 ? ? -69.81  90.57   
15 1 ASN A 376 ? ? -121.81 -169.98 
16 1 ASN A 400 ? ? -125.14 -168.21 
17 1 ALA A 528 ? ? 68.17   -5.06   
18 1 GLU A 533 ? ? -109.27 -64.72  
19 1 THR A 614 ? ? -94.36  54.41   
20 1 MET A 745 ? ? 73.09   -8.81   
21 1 GLN B 57  ? ? 41.08   -120.04 
22 1 ASP B 89  ? ? -66.19  -77.34  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG C 491 ? ? 0.095 'SIDE CHAIN' 
2 1 ARG C 525 ? ? 0.166 'SIDE CHAIN' 
3 1 ARG A 136 ? ? 0.260 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8XUM 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8XUM 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               2357026 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'structure of LGR4 with RSPO2' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8XUM 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8XUM 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8XUM 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 2   ? B MET 1   
2   1 Y 1 A PRO 3   ? B PRO 2   
3   1 Y 1 A GLY 4   ? B GLY 3   
4   1 Y 1 A PRO 5   ? B PRO 4   
5   1 Y 1 A LEU 6   ? B LEU 5   
6   1 Y 1 A GLY 7   ? B GLY 6   
7   1 Y 1 A LEU 8   ? B LEU 7   
8   1 Y 1 A LEU 9   ? B LEU 8   
9   1 Y 1 A CYS 10  ? B CYS 9   
10  1 Y 1 A PHE 11  ? B PHE 10  
11  1 Y 1 A LEU 12  ? B LEU 11  
12  1 Y 1 A ALA 13  ? B ALA 12  
13  1 Y 1 A LEU 14  ? B LEU 13  
14  1 Y 1 A GLY 15  ? B GLY 14  
15  1 Y 1 A LEU 16  ? B LEU 15  
16  1 Y 1 A LEU 17  ? B LEU 16  
17  1 Y 1 A GLY 18  ? B GLY 17  
18  1 Y 1 A SER 19  ? B SER 18  
19  1 Y 1 A ALA 20  ? B ALA 19  
20  1 Y 1 A GLY 21  ? B GLY 20  
21  1 Y 1 A PRO 22  ? B PRO 21  
22  1 Y 1 A SER 23  ? B SER 22  
23  1 Y 1 A GLY 24  ? B GLY 23  
24  1 Y 1 A ALA 25  ? B ALA 24  
25  1 Y 1 A ALA 26  ? B ALA 25  
26  1 Y 1 A PRO 27  ? B PRO 26  
27  1 Y 1 A PRO 28  ? B PRO 27  
28  1 Y 1 A LEU 29  ? B LEU 28  
29  1 Y 1 A CYS 30  ? B CYS 29  
30  1 Y 1 A ALA 31  ? B ALA 30  
31  1 Y 1 A ALA 32  ? B ALA 31  
32  1 Y 1 A TYR 479 A B TYR 479 
33  1 Y 1 A ALA 479 B B ALA 480 
34  1 Y 1 A ASN 479 C B ASN 481 
35  1 Y 1 A LEU 479 D B LEU 482 
36  1 Y 1 A ASN 479 E B ASN 483 
37  1 Y 1 A THR 479 F B THR 484 
38  1 Y 1 A GLU 479 G B GLU 485 
39  1 Y 1 A ASP 479 H B ASP 486 
40  1 Y 1 A ASN 479 I B ASN 487 
41  1 Y 1 A SER 479 J B SER 488 
42  1 Y 1 A LEU 479 K B LEU 489 
43  1 Y 1 A GLN 479 L B GLN 490 
44  1 Y 1 A ASP 479 M B ASP 491 
45  1 Y 1 A HIS 479 N B HIS 492 
46  1 Y 1 A SER 479 O B SER 493 
47  1 Y 1 A VAL 479 P B VAL 494 
48  1 Y 1 A ALA 479 Q B ALA 495 
49  1 Y 1 A GLN 479 R B GLN 496 
50  1 Y 1 A GLU 479 S B GLU 497 
51  1 Y 1 A LYS 479 T B LYS 498 
52  1 Y 1 A GLY 479 U B GLY 499 
53  1 Y 1 A THR 479 V B THR 500 
54  1 Y 1 A ALA 479 W B ALA 501 
55  1 Y 1 A ASP 479 X B ASP 502 
56  1 Y 1 A ALA 479 Y B ALA 503 
57  1 Y 1 A ALA 479 Z B ALA 504 
58  1 Y 1 A ASN 480 A B ASN 505 
59  1 Y 1 A VAL 480 B B VAL 506 
60  1 Y 1 A THR 480 C B THR 507 
61  1 Y 1 A SER 480 D B SER 508 
62  1 Y 1 A THR 480 E B THR 509 
63  1 Y 1 A LEU 480 F B LEU 510 
64  1 Y 1 A GLU 480 G B GLU 511 
65  1 Y 1 A ASN 480 H B ASN 512 
66  1 Y 1 A GLU 480 I B GLU 513 
67  1 Y 1 A GLU 480 J B GLU 514 
68  1 Y 1 A HIS 480 K B HIS 515 
69  1 Y 1 A ILE 650 ? B ILE 650 
70  1 Y 1 A MET 651 ? B MET 651 
71  1 Y 1 A LYS 652 ? B LYS 652 
72  1 Y 1 A ASN 653 ? B ASN 653 
73  1 Y 1 A GLY 654 ? B GLY 654 
74  1 Y 1 A LYS 655 ? B LYS 655 
75  1 Y 1 A SER 656 ? B SER 656 
76  1 Y 1 A GLU 733 ? B GLU 733 
77  1 Y 1 A LYS 734 ? B LYS 734 
78  1 Y 1 A GLU 735 ? B GLU 735 
79  1 Y 1 A ASP 736 ? B ASP 736 
80  1 Y 1 A LEU 737 ? B LEU 737 
81  1 Y 1 A SER 738 ? B SER 738 
82  1 Y 1 A GLU 739 ? B GLU 739 
83  1 Y 1 A ASN 740 ? B ASN 740 
84  1 Y 1 A LYS 822 ? B LYS 822 
85  1 Y 1 A SER 823 ? B SER 823 
86  1 Y 1 A GLY 824 ? B GLY 824 
87  1 Y 1 A SER 825 ? B SER 825 
88  1 Y 1 A VAL 826 ? B VAL 826 
89  1 Y 1 A SER 827 ? B SER 827 
90  1 Y 1 A VAL 828 ? B VAL 828 
91  1 Y 1 A SER 829 ? B SER 829 
92  1 Y 1 A ILE 830 ? B ILE 830 
93  1 Y 1 A SER 831 ? B SER 831 
94  1 Y 1 A SER 832 ? B SER 832 
95  1 Y 1 A GLN 833 ? B GLN 833 
96  1 Y 1 A GLY 834 ? B GLY 834 
97  1 Y 1 A GLY 835 ? B GLY 835 
98  1 Y 1 A CYS 836 ? B CYS 836 
99  1 Y 1 A LEU 837 ? B LEU 837 
100 1 Y 1 A GLU 838 ? B GLU 838 
101 1 Y 1 A GLN 839 ? B GLN 839 
102 1 Y 1 A ASP 840 ? B ASP 840 
103 1 Y 1 A PHE 841 ? B PHE 841 
104 1 Y 1 A TYR 842 ? B TYR 842 
105 1 Y 1 A TYR 843 ? B TYR 843 
106 1 Y 1 A ASP 844 ? B ASP 844 
107 1 Y 1 A CYS 845 ? B CYS 845 
108 1 Y 1 A GLY 846 ? B GLY 846 
109 1 Y 1 A MET 847 ? B MET 847 
110 1 Y 1 A TYR 848 ? B TYR 848 
111 1 Y 1 A SER 849 ? B SER 849 
112 1 Y 1 A HIS 850 ? B HIS 850 
113 1 Y 1 A LEU 851 ? B LEU 851 
114 1 Y 1 A GLN 852 ? B GLN 852 
115 1 Y 1 A GLY 853 ? B GLY 853 
116 1 Y 1 A ASN 854 ? B ASN 854 
117 1 Y 1 A LEU 855 ? B LEU 855 
118 1 Y 1 A THR 856 ? B THR 856 
119 1 Y 1 A VAL 857 ? B VAL 857 
120 1 Y 1 A CYS 858 ? B CYS 858 
121 1 Y 1 A ASP 859 ? B ASP 859 
122 1 Y 1 A CYS 860 ? B CYS 860 
123 1 Y 1 A CYS 861 ? B CYS 861 
124 1 Y 1 A GLU 862 ? B GLU 862 
125 1 Y 1 A SER 863 ? B SER 863 
126 1 Y 1 A PHE 864 ? B PHE 864 
127 1 Y 1 A LEU 865 ? B LEU 865 
128 1 Y 1 A LEU 866 ? B LEU 866 
129 1 Y 1 A THR 867 ? B THR 867 
130 1 Y 1 A LYS 868 ? B LYS 868 
131 1 Y 1 A PRO 869 ? B PRO 869 
132 1 Y 1 A VAL 870 ? B VAL 870 
133 1 Y 1 A SER 871 ? B SER 871 
134 1 Y 1 A CYS 872 ? B CYS 872 
135 1 Y 1 A LYS 873 ? B LYS 873 
136 1 Y 1 A HIS 874 ? B HIS 874 
137 1 Y 1 A LEU 875 ? B LEU 875 
138 1 Y 1 A ILE 876 ? B ILE 876 
139 1 Y 1 A LYS 877 ? B LYS 877 
140 1 Y 1 A SER 878 ? B SER 878 
141 1 Y 1 A HIS 879 ? B HIS 879 
142 1 Y 1 A SER 880 ? B SER 880 
143 1 Y 1 A CYS 881 ? B CYS 881 
144 1 Y 1 A PRO 882 ? B PRO 882 
145 1 Y 1 A ALA 883 ? B ALA 883 
146 1 Y 1 A LEU 884 ? B LEU 884 
147 1 Y 1 A ALA 885 ? B ALA 885 
148 1 Y 1 A VAL 886 ? B VAL 886 
149 1 Y 1 A ALA 887 ? B ALA 887 
150 1 Y 1 A SER 888 ? B SER 888 
151 1 Y 1 A CYS 889 ? B CYS 889 
152 1 Y 1 A GLN 890 ? B GLN 890 
153 1 Y 1 A ARG 891 ? B ARG 891 
154 1 Y 1 A PRO 892 ? B PRO 892 
155 1 Y 1 A GLU 893 ? B GLU 893 
156 1 Y 1 A GLY 894 ? B GLY 894 
157 1 Y 1 A TYR 895 ? B TYR 895 
158 1 Y 1 A TRP 896 ? B TRP 896 
159 1 Y 1 A SER 897 ? B SER 897 
160 1 Y 1 A ASP 898 ? B ASP 898 
161 1 Y 1 A CYS 899 ? B CYS 899 
162 1 Y 1 A GLY 900 ? B GLY 900 
163 1 Y 1 A THR 901 ? B THR 901 
164 1 Y 1 A GLN 902 ? B GLN 902 
165 1 Y 1 A SER 903 ? B SER 903 
166 1 Y 1 A ALA 904 ? B ALA 904 
167 1 Y 1 A HIS 905 ? B HIS 905 
168 1 Y 1 A SER 906 ? B SER 906 
169 1 Y 1 A ASP 907 ? B ASP 907 
170 1 Y 1 A TYR 908 ? B TYR 908 
171 1 Y 1 A ALA 909 ? B ALA 909 
172 1 Y 1 A ASP 910 ? B ASP 910 
173 1 Y 1 A GLU 911 ? B GLU 911 
174 1 Y 1 A GLU 912 ? B GLU 912 
175 1 Y 1 A ASP 913 ? B ASP 913 
176 1 Y 1 A SER 914 ? B SER 914 
177 1 Y 1 A PHE 915 ? B PHE 915 
178 1 Y 1 A VAL 916 ? B VAL 916 
179 1 Y 1 A SER 917 ? B SER 917 
180 1 Y 1 A ASP 918 ? B ASP 918 
181 1 Y 1 A SER 919 ? B SER 919 
182 1 Y 1 A SER 920 ? B SER 920 
183 1 Y 1 A ASP 921 ? B ASP 921 
184 1 Y 1 A GLN 922 ? B GLN 922 
185 1 Y 1 A VAL 923 ? B VAL 923 
186 1 Y 1 A GLN 924 ? B GLN 924 
187 1 Y 1 A ALA 925 ? B ALA 925 
188 1 Y 1 A CYS 926 ? B CYS 926 
189 1 Y 1 A GLY 927 ? B GLY 927 
190 1 Y 1 A ARG 928 ? B ARG 928 
191 1 Y 1 A ALA 929 ? B ALA 929 
192 1 Y 1 A CYS 930 ? B CYS 930 
193 1 Y 1 A PHE 931 ? B PHE 931 
194 1 Y 1 A TYR 932 ? B TYR 932 
195 1 Y 1 A GLN 933 ? B GLN 933 
196 1 Y 1 A SER 934 ? B SER 934 
197 1 Y 1 A ARG 935 ? B ARG 935 
198 1 Y 1 A GLY 936 ? B GLY 936 
199 1 Y 1 A PHE 937 ? B PHE 937 
200 1 Y 1 A PRO 938 ? B PRO 938 
201 1 Y 1 A LEU 939 ? B LEU 939 
202 1 Y 1 A VAL 940 ? B VAL 940 
203 1 Y 1 A ARG 941 ? B ARG 941 
204 1 Y 1 A TYR 942 ? B TYR 942 
205 1 Y 1 A ALA 943 ? B ALA 943 
206 1 Y 1 A TYR 944 ? B TYR 944 
207 1 Y 1 A ASN 945 ? B ASN 945 
208 1 Y 1 A LEU 946 ? B LEU 946 
209 1 Y 1 A PRO 947 ? B PRO 947 
210 1 Y 1 A ARG 948 ? B ARG 948 
211 1 Y 1 A VAL 949 ? B VAL 949 
212 1 Y 1 A LYS 950 ? B LYS 950 
213 1 Y 1 A ASP 951 ? B ASP 951 
214 1 Y 1 B MET 1   ? C MET 1   
215 1 Y 1 B GLN 2   ? C GLN 2   
216 1 Y 1 B PHE 3   ? C PHE 3   
217 1 Y 1 B ARG 4   ? C ARG 4   
218 1 Y 1 B LEU 5   ? C LEU 5   
219 1 Y 1 B PHE 6   ? C PHE 6   
220 1 Y 1 B SER 7   ? C SER 7   
221 1 Y 1 B PHE 8   ? C PHE 8   
222 1 Y 1 B ALA 9   ? C ALA 9   
223 1 Y 1 B LEU 10  ? C LEU 10  
224 1 Y 1 B ILE 11  ? C ILE 11  
225 1 Y 1 B ILE 12  ? C ILE 12  
226 1 Y 1 B LEU 13  ? C LEU 13  
227 1 Y 1 B ASN 14  ? C ASN 14  
228 1 Y 1 B CYS 15  ? C CYS 15  
229 1 Y 1 B MET 16  ? C MET 16  
230 1 Y 1 B ASP 17  ? C ASP 17  
231 1 Y 1 B TYR 18  ? C TYR 18  
232 1 Y 1 B SER 19  ? C SER 19  
233 1 Y 1 B HIS 20  ? C HIS 20  
234 1 Y 1 B CYS 21  ? C CYS 21  
235 1 Y 1 B GLN 22  ? C GLN 22  
236 1 Y 1 B GLY 23  ? C GLY 23  
237 1 Y 1 B ASN 24  ? C ASN 24  
238 1 Y 1 B ARG 25  ? C ARG 25  
239 1 Y 1 B TRP 26  ? C TRP 26  
240 1 Y 1 B ARG 27  ? C ARG 27  
241 1 Y 1 B ARG 28  ? C ARG 28  
242 1 Y 1 B SER 29  ? C SER 29  
243 1 Y 1 B LYS 30  ? C LYS 30  
244 1 Y 1 B ARG 31  ? C ARG 31  
245 1 Y 1 B ALA 32  ? C ALA 32  
246 1 Y 1 B SER 33  ? C SER 33  
247 1 Y 1 B TYR 34  ? C TYR 34  
248 1 Y 1 B VAL 35  ? C VAL 35  
249 1 Y 1 B SER 36  ? C SER 36  
250 1 Y 1 B ASN 37  ? C ASN 37  
251 1 Y 1 B PRO 38  ? C PRO 38  
252 1 Y 1 B VAL 142 ? C VAL 142 
253 1 Y 1 B GLU 143 ? C GLU 143 
254 1 Y 1 B GLY 144 ? C GLY 144 
255 1 Y 1 B CYS 145 ? C CYS 145 
256 1 Y 1 B GLU 146 ? C GLU 146 
257 1 Y 1 B VAL 147 ? C VAL 147 
258 1 Y 1 B GLY 148 ? C GLY 148 
259 1 Y 1 B HIS 149 ? C HIS 149 
260 1 Y 1 B TRP 150 ? C TRP 150 
261 1 Y 1 B SER 151 ? C SER 151 
262 1 Y 1 B GLU 152 ? C GLU 152 
263 1 Y 1 B TRP 153 ? C TRP 153 
264 1 Y 1 B GLY 154 ? C GLY 154 
265 1 Y 1 B THR 155 ? C THR 155 
266 1 Y 1 B CYS 156 ? C CYS 156 
267 1 Y 1 B SER 157 ? C SER 157 
268 1 Y 1 B ARG 158 ? C ARG 158 
269 1 Y 1 B ASN 159 ? C ASN 159 
270 1 Y 1 B ASN 160 ? C ASN 160 
271 1 Y 1 B ARG 161 ? C ARG 161 
272 1 Y 1 B THR 162 ? C THR 162 
273 1 Y 1 B CYS 163 ? C CYS 163 
274 1 Y 1 B GLY 164 ? C GLY 164 
275 1 Y 1 B PHE 165 ? C PHE 165 
276 1 Y 1 B LYS 166 ? C LYS 166 
277 1 Y 1 B TRP 167 ? C TRP 167 
278 1 Y 1 B GLY 168 ? C GLY 168 
279 1 Y 1 B LEU 169 ? C LEU 169 
280 1 Y 1 B GLU 170 ? C GLU 170 
281 1 Y 1 B THR 171 ? C THR 171 
282 1 Y 1 B ARG 172 ? C ARG 172 
283 1 Y 1 B THR 173 ? C THR 173 
284 1 Y 1 B ARG 174 ? C ARG 174 
285 1 Y 1 B GLN 175 ? C GLN 175 
286 1 Y 1 B ILE 176 ? C ILE 176 
287 1 Y 1 B VAL 177 ? C VAL 177 
288 1 Y 1 B LYS 178 ? C LYS 178 
289 1 Y 1 B LYS 179 ? C LYS 179 
290 1 Y 1 B PRO 180 ? C PRO 180 
291 1 Y 1 B VAL 181 ? C VAL 181 
292 1 Y 1 B LYS 182 ? C LYS 182 
293 1 Y 1 B ASP 183 ? C ASP 183 
294 1 Y 1 B THR 184 ? C THR 184 
295 1 Y 1 B ILE 185 ? C ILE 185 
296 1 Y 1 B LEU 186 ? C LEU 186 
297 1 Y 1 B CYS 187 ? C CYS 187 
298 1 Y 1 B PRO 188 ? C PRO 188 
299 1 Y 1 B THR 189 ? C THR 189 
300 1 Y 1 B ILE 190 ? C ILE 190 
301 1 Y 1 B ALA 191 ? C ALA 191 
302 1 Y 1 B GLU 192 ? C GLU 192 
303 1 Y 1 B SER 193 ? C SER 193 
304 1 Y 1 B ARG 194 ? C ARG 194 
305 1 Y 1 B ARG 195 ? C ARG 195 
306 1 Y 1 B CYS 196 ? C CYS 196 
307 1 Y 1 B LYS 197 ? C LYS 197 
308 1 Y 1 B MET 198 ? C MET 198 
309 1 Y 1 B THR 199 ? C THR 199 
310 1 Y 1 B MET 200 ? C MET 200 
311 1 Y 1 B ARG 201 ? C ARG 201 
312 1 Y 1 B HIS 202 ? C HIS 202 
313 1 Y 1 B CYS 203 ? C CYS 203 
314 1 Y 1 B PRO 204 ? C PRO 204 
315 1 Y 1 B GLY 205 ? C GLY 205 
316 1 Y 1 B GLY 206 ? C GLY 206 
317 1 Y 1 B LYS 207 ? C LYS 207 
318 1 Y 1 B ARG 208 ? C ARG 208 
319 1 Y 1 B THR 209 ? C THR 209 
320 1 Y 1 B PRO 210 ? C PRO 210 
321 1 Y 1 B LYS 211 ? C LYS 211 
322 1 Y 1 B ALA 212 ? C ALA 212 
323 1 Y 1 B LYS 213 ? C LYS 213 
324 1 Y 1 B GLU 214 ? C GLU 214 
325 1 Y 1 B LYS 215 ? C LYS 215 
326 1 Y 1 B ARG 216 ? C ARG 216 
327 1 Y 1 B ASN 217 ? C ASN 217 
328 1 Y 1 B LYS 218 ? C LYS 218 
329 1 Y 1 B LYS 219 ? C LYS 219 
330 1 Y 1 B LYS 220 ? C LYS 220 
331 1 Y 1 B LYS 221 ? C LYS 221 
332 1 Y 1 B ARG 222 ? C ARG 222 
333 1 Y 1 B LYS 223 ? C LYS 223 
334 1 Y 1 B LEU 224 ? C LEU 224 
335 1 Y 1 B ILE 225 ? C ILE 225 
336 1 Y 1 B GLU 226 ? C GLU 226 
337 1 Y 1 B ARG 227 ? C ARG 227 
338 1 Y 1 B ALA 228 ? C ALA 228 
339 1 Y 1 B GLN 229 ? C GLN 229 
340 1 Y 1 B GLU 230 ? C GLU 230 
341 1 Y 1 B GLN 231 ? C GLN 231 
342 1 Y 1 B HIS 232 ? C HIS 232 
343 1 Y 1 B SER 233 ? C SER 233 
344 1 Y 1 B VAL 234 ? C VAL 234 
345 1 Y 1 B PHE 235 ? C PHE 235 
346 1 Y 1 B LEU 236 ? C LEU 236 
347 1 Y 1 B ALA 237 ? C ALA 237 
348 1 Y 1 B THR 238 ? C THR 238 
349 1 Y 1 B ASP 239 ? C ASP 239 
350 1 Y 1 B ARG 240 ? C ARG 240 
351 1 Y 1 B ALA 241 ? C ALA 241 
352 1 Y 1 B ASN 242 ? C ASN 242 
353 1 Y 1 B GLN 243 ? C GLN 243 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-01-13 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8XUM 
_em_admin.last_update        2025-01-15 
_em_admin.map_release_date   2025-01-15 
_em_admin.title              'Structure of LGR4 with RSPO2' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         1.944 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'              ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 3  ? ? 1 ?      ?            
MASKING                         ? 4  ? ? ? ?      ?            
'CTF CORRECTION'                ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'            ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?      ?            
'MODEL FITTING'                 ? 8  ? ? ? ?      ?            
OTHER                           ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ?            
CLASSIFICATION                  ? 12 1 ? ? ?      ?            
RECONSTRUCTION                  ? 13 1 ? ? ?      ?            
'VOLUME SELECTION'              ? 14 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8XUM 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . GLY A 1 1   ? 76.733  76.950  117.086 1.00 195.65 ? 441 GLY C N   1 
ATOM 2    C CA  . GLY A 1 1   ? 76.461  75.540  117.296 1.00 196.97 ? 441 GLY C CA  1 
ATOM 3    C C   . GLY A 1 1   ? 76.855  75.047  118.675 1.00 196.91 ? 441 GLY C C   1 
ATOM 4    O O   . GLY A 1 1   ? 77.210  75.837  119.548 1.00 195.35 ? 441 GLY C O   1 
ATOM 5    N N   . SER A 1 2   ? 76.790  73.732  118.867 1.00 197.49 ? 442 SER C N   1 
ATOM 6    C CA  . SER A 1 2   ? 77.150  73.118  120.136 1.00 197.08 ? 442 SER C CA  1 
ATOM 7    C C   . SER A 1 2   ? 77.742  71.755  119.812 1.00 197.44 ? 442 SER C C   1 
ATOM 8    O O   . SER A 1 2   ? 77.361  71.129  118.820 1.00 197.18 ? 442 SER C O   1 
ATOM 9    C CB  . SER A 1 2   ? 75.926  72.954  121.046 1.00 196.42 ? 442 SER C CB  1 
ATOM 10   O OG  . SER A 1 2   ? 75.600  74.172  121.690 1.00 197.01 ? 442 SER C OG  1 
ATOM 11   N N   . LEU A 1 3   ? 78.706  71.315  120.640 1.00 190.29 ? 443 LEU C N   1 
ATOM 12   C CA  . LEU A 1 3   ? 79.446  70.057  120.369 1.00 189.29 ? 443 LEU C CA  1 
ATOM 13   C C   . LEU A 1 3   ? 79.810  69.316  121.663 1.00 188.37 ? 443 LEU C C   1 
ATOM 14   O O   . LEU A 1 3   ? 80.167  69.991  122.642 1.00 186.06 ? 443 LEU C O   1 
ATOM 15   C CB  . LEU A 1 3   ? 80.721  70.384  119.592 1.00 188.26 ? 443 LEU C CB  1 
ATOM 16   C CG  . LEU A 1 3   ? 80.596  71.285  118.358 1.00 188.77 ? 443 LEU C CG  1 
ATOM 17   C CD1 . LEU A 1 3   ? 80.484  72.777  118.630 1.00 188.12 ? 443 LEU C CD1 1 
ATOM 18   C CD2 . LEU A 1 3   ? 81.810  71.024  117.498 1.00 188.35 ? 443 LEU C CD2 1 
ATOM 19   N N   . ARG A 1 4   ? 79.711  67.987  121.679 1.00 187.76 ? 444 ARG C N   1 
ATOM 20   C CA  . ARG A 1 4   ? 80.134  67.126  122.784 1.00 187.95 ? 444 ARG C CA  1 
ATOM 21   C C   . ARG A 1 4   ? 81.557  66.616  122.874 1.00 188.89 ? 444 ARG C C   1 
ATOM 22   O O   . ARG A 1 4   ? 81.998  65.869  121.995 1.00 188.50 ? 444 ARG C O   1 
ATOM 23   C CB  . ARG A 1 4   ? 79.281  65.865  122.627 1.00 186.49 ? 444 ARG C CB  1 
ATOM 24   C CG  . ARG A 1 4   ? 79.406  64.823  123.729 1.00 186.75 ? 444 ARG C CG  1 
ATOM 25   C CD  . ARG A 1 4   ? 79.074  65.439  125.075 1.00 186.86 ? 444 ARG C CD  1 
ATOM 26   N NE  . ARG A 1 4   ? 77.757  66.061  125.203 1.00 187.25 ? 444 ARG C NE  1 
ATOM 27   C CZ  . ARG A 1 4   ? 76.624  65.438  125.508 1.00 187.68 ? 444 ARG C CZ  1 
ATOM 28   N NH1 . ARG A 1 4   ? 76.578  64.133  125.722 1.00 186.92 ? 444 ARG C NH1 1 
ATOM 29   N NH2 . ARG A 1 4   ? 75.495  66.140  125.560 1.00 187.13 ? 444 ARG C NH2 1 
ATOM 30   N N   . LEU A 1 5   ? 82.295  67.054  123.891 1.00 178.39 ? 445 LEU C N   1 
ATOM 31   C CA  . LEU A 1 5   ? 83.660  66.599  124.120 1.00 176.63 ? 445 LEU C CA  1 
ATOM 32   C C   . LEU A 1 5   ? 83.710  65.752  125.381 1.00 177.69 ? 445 LEU C C   1 
ATOM 33   O O   . LEU A 1 5   ? 83.607  66.281  126.490 1.00 177.68 ? 445 LEU C O   1 
ATOM 34   C CB  . LEU A 1 5   ? 84.766  67.660  124.145 1.00 174.96 ? 445 LEU C CB  1 
ATOM 35   C CG  . LEU A 1 5   ? 84.862  68.706  123.028 1.00 175.52 ? 445 LEU C CG  1 
ATOM 36   C CD1 . LEU A 1 5   ? 84.786  68.045  121.658 1.00 174.96 ? 445 LEU C CD1 1 
ATOM 37   C CD2 . LEU A 1 5   ? 83.815  69.801  123.165 1.00 175.88 ? 445 LEU C CD2 1 
ATOM 38   N N   . SER A 1 6   ? 83.862  64.442  125.211 1.00 182.55 ? 446 SER C N   1 
ATOM 39   C CA  . SER A 1 6   ? 83.809  63.497  126.318 1.00 182.56 ? 446 SER C CA  1 
ATOM 40   C C   . SER A 1 6   ? 85.146  62.788  126.454 1.00 182.39 ? 446 SER C C   1 
ATOM 41   O O   . SER A 1 6   ? 85.692  62.288  125.464 1.00 181.32 ? 446 SER C O   1 
ATOM 42   C CB  . SER A 1 6   ? 82.690  62.473  126.113 1.00 182.37 ? 446 SER C CB  1 
ATOM 43   O OG  . SER A 1 6   ? 82.875  61.348  126.953 1.00 183.22 ? 446 SER C OG  1 
ATOM 44   N N   . CYS A 1 7   ? 85.668  62.745  127.677 1.00 187.93 ? 447 CYS C N   1 
ATOM 45   C CA  . CYS A 1 7   ? 86.895  62.021  127.976 1.00 188.14 ? 447 CYS C CA  1 
ATOM 46   C C   . CYS A 1 7   ? 86.625  61.067  129.131 1.00 190.45 ? 447 CYS C C   1 
ATOM 47   O O   . CYS A 1 7   ? 86.101  61.475  130.174 1.00 192.46 ? 447 CYS C O   1 
ATOM 48   C CB  . CYS A 1 7   ? 88.040  62.987  128.306 1.00 188.29 ? 447 CYS C CB  1 
ATOM 49   S SG  . CYS A 1 7   ? 89.450  62.263  129.170 1.00 191.17 ? 447 CYS C SG  1 
ATOM 50   N N   . ALA A 1 8   ? 86.978  59.800  128.937 1.00 195.86 ? 448 ALA C N   1 
ATOM 51   C CA  . ALA A 1 8   ? 86.692  58.735  129.884 1.00 196.86 ? 448 ALA C CA  1 
ATOM 52   C C   . ALA A 1 8   ? 87.987  58.172  130.452 1.00 196.28 ? 448 ALA C C   1 
ATOM 53   O O   . ALA A 1 8   ? 89.083  58.426  129.944 1.00 194.60 ? 448 ALA C O   1 
ATOM 54   C CB  . ALA A 1 8   ? 85.873  57.617  129.226 1.00 195.09 ? 448 ALA C CB  1 
ATOM 55   N N   . ALA A 1 9   ? 87.846  57.395  131.522 1.00 200.91 ? 449 ALA C N   1 
ATOM 56   C CA  . ALA A 1 9   ? 88.989  56.768  132.172 1.00 201.12 ? 449 ALA C CA  1 
ATOM 57   C C   . ALA A 1 9   ? 89.358  55.489  131.432 1.00 201.55 ? 449 ALA C C   1 
ATOM 58   O O   . ALA A 1 9   ? 88.536  54.574  131.314 1.00 200.85 ? 449 ALA C O   1 
ATOM 59   C CB  . ALA A 1 9   ? 88.675  56.474  133.637 1.00 200.90 ? 449 ALA C CB  1 
ATOM 60   N N   . SER A 1 10  ? 90.593  55.431  130.927 1.00 201.45 ? 450 SER C N   1 
ATOM 61   C CA  . SER A 1 10  ? 91.046  54.239  130.217 1.00 201.67 ? 450 SER C CA  1 
ATOM 62   C C   . SER A 1 10  ? 91.084  53.027  131.140 1.00 201.50 ? 450 SER C C   1 
ATOM 63   O O   . SER A 1 10  ? 90.647  51.934  130.761 1.00 201.42 ? 450 SER C O   1 
ATOM 64   C CB  . SER A 1 10  ? 92.423  54.489  129.603 1.00 200.12 ? 450 SER C CB  1 
ATOM 65   O OG  . SER A 1 10  ? 92.542  55.824  129.143 1.00 197.65 ? 450 SER C OG  1 
ATOM 66   N N   . GLY A 1 11  ? 91.600  53.201  132.353 1.00 205.20 ? 451 GLY C N   1 
ATOM 67   C CA  . GLY A 1 11  ? 91.683  52.115  133.309 1.00 204.50 ? 451 GLY C CA  1 
ATOM 68   C C   . GLY A 1 11  ? 90.931  52.397  134.592 1.00 205.19 ? 451 GLY C C   1 
ATOM 69   O O   . GLY A 1 11  ? 89.704  52.536  134.588 1.00 204.40 ? 451 GLY C O   1 
ATOM 70   N N   . TYR A 1 12  ? 91.664  52.475  135.700 1.00 211.66 ? 452 TYR C N   1 
ATOM 71   C CA  . TYR A 1 12  ? 91.061  52.799  136.985 1.00 212.10 ? 452 TYR C CA  1 
ATOM 72   C C   . TYR A 1 12  ? 90.463  54.202  136.942 1.00 212.70 ? 452 TYR C C   1 
ATOM 73   O O   . TYR A 1 12  ? 90.962  55.091  136.248 1.00 212.20 ? 452 TYR C O   1 
ATOM 74   C CB  . TYR A 1 12  ? 92.110  52.681  138.095 1.00 211.26 ? 452 TYR C CB  1 
ATOM 75   C CG  . TYR A 1 12  ? 91.859  53.526  139.323 1.00 212.14 ? 452 TYR C CG  1 
ATOM 76   C CD1 . TYR A 1 12  ? 90.913  53.149  140.268 1.00 211.63 ? 452 TYR C CD1 1 
ATOM 77   C CD2 . TYR A 1 12  ? 92.584  54.688  139.550 1.00 210.95 ? 452 TYR C CD2 1 
ATOM 78   C CE1 . TYR A 1 12  ? 90.689  53.912  141.398 1.00 211.65 ? 452 TYR C CE1 1 
ATOM 79   C CE2 . TYR A 1 12  ? 92.366  55.458  140.677 1.00 211.28 ? 452 TYR C CE2 1 
ATOM 80   C CZ  . TYR A 1 12  ? 91.416  55.066  141.596 1.00 212.30 ? 452 TYR C CZ  1 
ATOM 81   O OH  . TYR A 1 12  ? 91.196  55.830  142.719 1.00 210.74 ? 452 TYR C OH  1 
ATOM 82   N N   . THR A 1 13  ? 89.367  54.387  137.678 1.00 208.41 ? 453 THR C N   1 
ATOM 83   C CA  . THR A 1 13  ? 88.600  55.625  137.596 1.00 207.45 ? 453 THR C CA  1 
ATOM 84   C C   . THR A 1 13  ? 89.455  56.837  137.950 1.00 207.87 ? 453 THR C C   1 
ATOM 85   O O   . THR A 1 13  ? 90.198  56.829  138.936 1.00 208.34 ? 453 THR C O   1 
ATOM 86   C CB  . THR A 1 13  ? 87.375  55.549  138.512 1.00 205.30 ? 453 THR C CB  1 
ATOM 87   O OG1 . THR A 1 13  ? 86.704  56.815  138.527 1.00 205.31 ? 453 THR C OG1 1 
ATOM 88   C CG2 . THR A 1 13  ? 87.768  55.159  139.931 1.00 204.16 ? 453 THR C CG2 1 
ATOM 89   N N   . TYR A 1 14  ? 89.356  57.877  137.125 1.00 196.06 ? 454 TYR C N   1 
ATOM 90   C CA  . TYR A 1 14  ? 90.083  59.122  137.328 1.00 194.63 ? 454 TYR C CA  1 
ATOM 91   C C   . TYR A 1 14  ? 89.264  60.172  138.068 1.00 194.01 ? 454 TYR C C   1 
ATOM 92   O O   . TYR A 1 14  ? 89.791  61.247  138.376 1.00 191.45 ? 454 TYR C O   1 
ATOM 93   C CB  . TYR A 1 14  ? 90.546  59.684  135.980 1.00 193.79 ? 454 TYR C CB  1 
ATOM 94   C CG  . TYR A 1 14  ? 91.450  58.754  135.199 1.00 194.80 ? 454 TYR C CG  1 
ATOM 95   C CD1 . TYR A 1 14  ? 92.320  57.889  135.850 1.00 194.03 ? 454 TYR C CD1 1 
ATOM 96   C CD2 . TYR A 1 14  ? 91.439  58.747  133.810 1.00 193.42 ? 454 TYR C CD2 1 
ATOM 97   C CE1 . TYR A 1 14  ? 93.150  57.039  135.140 1.00 192.76 ? 454 TYR C CE1 1 
ATOM 98   C CE2 . TYR A 1 14  ? 92.264  57.900  133.092 1.00 192.86 ? 454 TYR C CE2 1 
ATOM 99   C CZ  . TYR A 1 14  ? 93.117  57.049  133.762 1.00 192.50 ? 454 TYR C CZ  1 
ATOM 100  O OH  . TYR A 1 14  ? 93.940  56.205  133.052 1.00 190.22 ? 454 TYR C OH  1 
ATOM 101  N N   . SER A 1 15  ? 87.999  59.886  138.359 1.00 195.09 ? 455 SER C N   1 
ATOM 102  C CA  . SER A 1 15  ? 87.107  60.780  139.089 1.00 193.83 ? 455 SER C CA  1 
ATOM 103  C C   . SER A 1 15  ? 87.501  61.027  140.548 1.00 193.13 ? 455 SER C C   1 
ATOM 104  O O   . SER A 1 15  ? 87.154  62.088  141.084 1.00 192.49 ? 455 SER C O   1 
ATOM 105  C CB  . SER A 1 15  ? 85.674  60.243  139.030 1.00 192.94 ? 455 SER C CB  1 
ATOM 106  O OG  . SER A 1 15  ? 85.592  58.919  139.526 1.00 192.85 ? 455 SER C OG  1 
ATOM 107  N N   . PRO A 1 16  ? 88.199  60.090  141.252 1.00 183.89 ? 456 PRO C N   1 
ATOM 108  C CA  . PRO A 1 16  ? 88.590  60.370  142.644 1.00 182.77 ? 456 PRO C CA  1 
ATOM 109  C C   . PRO A 1 16  ? 89.306  61.692  142.896 1.00 181.83 ? 456 PRO C C   1 
ATOM 110  O O   . PRO A 1 16  ? 89.471  62.074  144.059 1.00 182.45 ? 456 PRO C O   1 
ATOM 111  C CB  . PRO A 1 16  ? 89.501  59.185  142.980 1.00 180.81 ? 456 PRO C CB  1 
ATOM 112  C CG  . PRO A 1 16  ? 88.888  58.070  142.247 1.00 180.94 ? 456 PRO C CG  1 
ATOM 113  C CD  . PRO A 1 16  ? 88.372  58.653  140.953 1.00 182.54 ? 456 PRO C CD  1 
ATOM 114  N N   . TYR A 1 17  ? 89.837  62.332  141.849 1.00 157.30 ? 457 TYR C N   1 
ATOM 115  C CA  . TYR A 1 17  ? 90.404  63.690  142.049 1.00 155.32 ? 457 TYR C CA  1 
ATOM 116  C C   . TYR A 1 17  ? 90.129  64.525  140.818 1.00 156.16 ? 457 TYR C C   1 
ATOM 117  O O   . TYR A 1 17  ? 89.451  64.004  139.917 1.00 154.94 ? 457 TYR C O   1 
ATOM 118  C CB  . TYR A 1 17  ? 91.873  63.668  142.478 1.00 156.55 ? 457 TYR C CB  1 
ATOM 119  C CG  . TYR A 1 17  ? 92.196  64.658  143.586 1.00 157.15 ? 457 TYR C CG  1 
ATOM 120  C CD1 . TYR A 1 17  ? 91.713  64.483  144.874 1.00 157.94 ? 457 TYR C CD1 1 
ATOM 121  C CD2 . TYR A 1 17  ? 92.974  65.780  143.334 1.00 158.00 ? 457 TYR C CD2 1 
ATOM 122  C CE1 . TYR A 1 17  ? 91.999  65.388  145.879 1.00 155.98 ? 457 TYR C CE1 1 
ATOM 123  C CE2 . TYR A 1 17  ? 93.264  66.696  144.329 1.00 158.00 ? 457 TYR C CE2 1 
ATOM 124  C CZ  . TYR A 1 17  ? 92.777  66.497  145.606 1.00 156.53 ? 457 TYR C CZ  1 
ATOM 125  O OH  . TYR A 1 17  ? 93.048  67.387  146.600 1.00 155.62 ? 457 TYR C OH  1 
ATOM 126  N N   . CYS A 1 18  ? 90.692  65.725  140.731 1.00 158.25 ? 458 CYS C N   1 
ATOM 127  C CA  . CYS A 1 18  ? 90.354  66.735  139.737 1.00 160.21 ? 458 CYS C CA  1 
ATOM 128  C C   . CYS A 1 18  ? 90.722  66.291  138.326 1.00 158.35 ? 458 CYS C C   1 
ATOM 129  O O   . CYS A 1 18  ? 91.759  65.662  138.100 1.00 158.30 ? 458 CYS C O   1 
ATOM 130  C CB  . CYS A 1 18  ? 91.060  68.050  140.065 1.00 157.27 ? 458 CYS C CB  1 
ATOM 131  S SG  . CYS A 1 18  ? 92.859  67.928  140.164 1.00 156.82 ? 458 CYS C SG  1 
ATOM 132  N N   . MET A 1 19  ? 89.849  66.621  137.374 1.00 158.73 ? 459 MET C N   1 
ATOM 133  C CA  . MET A 1 19  ? 90.075  66.386  135.956 1.00 155.61 ? 459 MET C CA  1 
ATOM 134  C C   . MET A 1 19  ? 89.677  67.635  135.183 1.00 157.27 ? 459 MET C C   1 
ATOM 135  O O   . MET A 1 19  ? 88.743  68.345  135.562 1.00 162.49 ? 459 MET C O   1 
ATOM 136  C CB  . MET A 1 19  ? 89.284  65.166  135.454 1.00 156.09 ? 459 MET C CB  1 
ATOM 137  C CG  . MET A 1 19  ? 89.265  64.001  136.437 1.00 157.68 ? 459 MET C CG  1 
ATOM 138  S SD  . MET A 1 19  ? 87.972  62.782  136.138 1.00 163.58 ? 459 MET C SD  1 
ATOM 139  C CE  . MET A 1 19  ? 87.752  62.940  134.371 1.00 158.09 ? 459 MET C CE  1 
ATOM 140  N N   . GLY A 1 20  ? 90.392  67.909  134.092 1.00 148.26 ? 460 GLY C N   1 
ATOM 141  C CA  . GLY A 1 20  ? 90.173  69.151  133.379 1.00 147.68 ? 460 GLY C CA  1 
ATOM 142  C C   . GLY A 1 20  ? 90.358  69.015  131.884 1.00 147.49 ? 460 GLY C C   1 
ATOM 143  O O   . GLY A 1 20  ? 90.776  67.975  131.373 1.00 150.15 ? 460 GLY C O   1 
ATOM 144  N N   . TRP A 1 21  ? 90.026  70.097  131.185 1.00 148.63 ? 461 TRP C N   1 
ATOM 145  C CA  . TRP A 1 21  ? 90.197  70.202  129.745 1.00 150.79 ? 461 TRP C CA  1 
ATOM 146  C C   . TRP A 1 21  ? 91.111  71.378  129.439 1.00 152.74 ? 461 TRP C C   1 
ATOM 147  O O   . TRP A 1 21  ? 90.894  72.490  129.943 1.00 153.53 ? 461 TRP C O   1 
ATOM 148  C CB  . TRP A 1 21  ? 88.852  70.372  129.036 1.00 152.19 ? 461 TRP C CB  1 
ATOM 149  C CG  . TRP A 1 21  ? 88.059  69.108  128.966 1.00 154.30 ? 461 TRP C CG  1 
ATOM 150  C CD1 . TRP A 1 21  ? 87.331  68.546  129.969 1.00 153.69 ? 461 TRP C CD1 1 
ATOM 151  C CD2 . TRP A 1 21  ? 87.920  68.242  127.834 1.00 154.43 ? 461 TRP C CD2 1 
ATOM 152  N NE1 . TRP A 1 21  ? 86.741  67.386  129.534 1.00 155.47 ? 461 TRP C NE1 1 
ATOM 153  C CE2 . TRP A 1 21  ? 87.088  67.176  128.226 1.00 155.33 ? 461 TRP C CE2 1 
ATOM 154  C CE3 . TRP A 1 21  ? 88.416  68.265  126.528 1.00 152.31 ? 461 TRP C CE3 1 
ATOM 155  C CZ2 . TRP A 1 21  ? 86.741  66.143  127.360 1.00 153.81 ? 461 TRP C CZ2 1 
ATOM 156  C CZ3 . TRP A 1 21  ? 88.070  67.238  125.670 1.00 152.91 ? 461 TRP C CZ3 1 
ATOM 157  C CH2 . TRP A 1 21  ? 87.242  66.191  126.090 1.00 153.09 ? 461 TRP C CH2 1 
ATOM 158  N N   . PHE A 1 22  ? 92.124  71.124  128.611 1.00 133.12 ? 462 PHE C N   1 
ATOM 159  C CA  . PHE A 1 22  ? 93.132  72.102  128.237 1.00 128.90 ? 462 PHE C CA  1 
ATOM 160  C C   . PHE A 1 22  ? 93.126  72.283  126.726 1.00 127.27 ? 462 PHE C C   1 
ATOM 161  O O   . PHE A 1 22  ? 92.737  71.381  125.981 1.00 125.71 ? 462 PHE C O   1 
ATOM 162  C CB  . PHE A 1 22  ? 94.535  71.665  128.683 1.00 127.96 ? 462 PHE C CB  1 
ATOM 163  C CG  . PHE A 1 22  ? 94.747  71.698  130.168 1.00 127.65 ? 462 PHE C CG  1 
ATOM 164  C CD1 . PHE A 1 22  ? 94.073  70.823  131.001 1.00 128.57 ? 462 PHE C CD1 1 
ATOM 165  C CD2 . PHE A 1 22  ? 95.643  72.589  130.728 1.00 127.73 ? 462 PHE C CD2 1 
ATOM 166  C CE1 . PHE A 1 22  ? 94.273  70.852  132.363 1.00 130.08 ? 462 PHE C CE1 1 
ATOM 167  C CE2 . PHE A 1 22  ? 95.846  72.624  132.090 1.00 128.30 ? 462 PHE C CE2 1 
ATOM 168  C CZ  . PHE A 1 22  ? 95.162  71.754  132.909 1.00 130.19 ? 462 PHE C CZ  1 
ATOM 169  N N   . ARG A 1 23  ? 93.561  73.455  126.277 1.00 129.23 ? 463 ARG C N   1 
ATOM 170  C CA  . ARG A 1 23  ? 93.710  73.725  124.855 1.00 132.14 ? 463 ARG C CA  1 
ATOM 171  C C   . ARG A 1 23  ? 95.084  74.320  124.598 1.00 133.94 ? 463 ARG C C   1 
ATOM 172  O O   . ARG A 1 23  ? 95.588  75.115  125.396 1.00 134.41 ? 463 ARG C O   1 
ATOM 173  C CB  . ARG A 1 23  ? 92.617  74.668  124.336 1.00 136.85 ? 463 ARG C CB  1 
ATOM 174  C CG  . ARG A 1 23  ? 92.337  75.867  125.219 1.00 135.42 ? 463 ARG C CG  1 
ATOM 175  C CD  . ARG A 1 23  ? 91.005  76.501  124.853 1.00 130.41 ? 463 ARG C CD  1 
ATOM 176  N NE  . ARG A 1 23  ? 91.142  77.537  123.837 1.00 134.04 ? 463 ARG C NE  1 
ATOM 177  C CZ  . ARG A 1 23  ? 91.586  78.764  124.070 1.00 134.38 ? 463 ARG C CZ  1 
ATOM 178  N NH1 . ARG A 1 23  ? 91.949  79.150  125.282 1.00 132.57 ? 463 ARG C NH1 1 
ATOM 179  N NH2 . ARG A 1 23  ? 91.663  79.628  123.061 1.00 134.37 ? 463 ARG C NH2 1 
ATOM 180  N N   . GLN A 1 24  ? 95.685  73.926  123.480 1.00 130.57 ? 464 GLN C N   1 
ATOM 181  C CA  . GLN A 1 24  ? 97.040  74.316  123.121 1.00 132.03 ? 464 GLN C CA  1 
ATOM 182  C C   . GLN A 1 24  ? 97.025  74.930  121.731 1.00 132.23 ? 464 GLN C C   1 
ATOM 183  O O   . GLN A 1 24  ? 96.579  74.290  120.772 1.00 131.68 ? 464 GLN C O   1 
ATOM 184  C CB  . GLN A 1 24  ? 97.980  73.110  123.160 1.00 134.40 ? 464 GLN C CB  1 
ATOM 185  C CG  . GLN A 1 24  ? 99.340  73.360  122.537 1.00 133.57 ? 464 GLN C CG  1 
ATOM 186  C CD  . GLN A 1 24  ? 100.418 72.476  123.126 1.00 135.64 ? 464 GLN C CD  1 
ATOM 187  O OE1 . GLN A 1 24  ? 100.290 71.252  123.148 1.00 135.21 ? 464 GLN C OE1 1 
ATOM 188  N NE2 . GLN A 1 24  ? 101.488 73.092  123.612 1.00 136.38 ? 464 GLN C NE2 1 
ATOM 189  N N   . ALA A 1 25  ? 97.504  76.165  121.627 1.00 141.36 ? 465 ALA C N   1 
ATOM 190  C CA  . ALA A 1 25  ? 97.712  76.768  120.324 1.00 142.80 ? 465 ALA C CA  1 
ATOM 191  C C   . ALA A 1 25  ? 98.903  76.102  119.636 1.00 143.07 ? 465 ALA C C   1 
ATOM 192  O O   . ALA A 1 25  ? 99.819  75.616  120.304 1.00 144.27 ? 465 ALA C O   1 
ATOM 193  C CB  . ALA A 1 25  ? 97.953  78.268  120.460 1.00 141.09 ? 465 ALA C CB  1 
ATOM 194  N N   . PRO A 1 26  ? 98.908  76.055  118.299 1.00 144.90 ? 466 PRO C N   1 
ATOM 195  C CA  . PRO A 1 26  ? 99.999  75.367  117.592 1.00 145.64 ? 466 PRO C CA  1 
ATOM 196  C C   . PRO A 1 26  ? 101.375 75.915  117.936 1.00 147.25 ? 466 PRO C C   1 
ATOM 197  O O   . PRO A 1 26  ? 101.700 77.060  117.609 1.00 146.89 ? 466 PRO C O   1 
ATOM 198  C CB  . PRO A 1 26  ? 99.659  75.601  116.115 1.00 143.72 ? 466 PRO C CB  1 
ATOM 199  C CG  . PRO A 1 26  ? 98.187  75.816  116.099 1.00 144.20 ? 466 PRO C CG  1 
ATOM 200  C CD  . PRO A 1 26  ? 97.870  76.539  117.374 1.00 144.04 ? 466 PRO C CD  1 
ATOM 201  N N   . GLY A 1 27  ? 102.189 75.094  118.598 1.00 147.34 ? 467 GLY C N   1 
ATOM 202  C CA  . GLY A 1 27  ? 103.550 75.447  118.938 1.00 144.14 ? 467 GLY C CA  1 
ATOM 203  C C   . GLY A 1 27  ? 103.883 76.207  120.204 1.00 143.62 ? 467 GLY C C   1 
ATOM 204  O O   . GLY A 1 27  ? 105.070 76.378  120.506 1.00 141.99 ? 467 GLY C O   1 
ATOM 205  N N   . LYS A 1 28  ? 102.887 76.664  120.957 1.00 138.97 ? 468 LYS C N   1 
ATOM 206  C CA  . LYS A 1 28  ? 103.105 77.329  122.235 1.00 136.32 ? 468 LYS C CA  1 
ATOM 207  C C   . LYS A 1 28  ? 102.510 76.501  123.348 1.00 136.94 ? 468 LYS C C   1 
ATOM 208  O O   . LYS A 1 28  ? 102.081 75.366  123.119 1.00 137.37 ? 468 LYS C O   1 
ATOM 209  C CB  . LYS A 1 28  ? 102.576 78.771  122.257 1.00 135.90 ? 468 LYS C CB  1 
ATOM 210  C CG  . LYS A 1 28  ? 103.283 79.840  121.404 1.00 136.73 ? 468 LYS C CG  1 
ATOM 211  C CD  . LYS A 1 28  ? 102.710 81.253  121.533 1.00 139.25 ? 468 LYS C CD  1 
ATOM 212  C CE  . LYS A 1 28  ? 101.315 81.345  120.936 1.00 138.74 ? 468 LYS C CE  1 
ATOM 213  N NZ  . LYS A 1 28  ? 101.314 81.070  119.474 1.00 139.01 ? 468 LYS C NZ  1 
ATOM 214  N N   . ALA A 1 29  ? 102.491 77.051  124.558 1.00 123.65 ? 469 ALA C N   1 
ATOM 215  C CA  . ALA A 1 29  ? 102.046 76.306  125.726 1.00 124.19 ? 469 ALA C CA  1 
ATOM 216  C C   . ALA A 1 29  ? 100.606 75.813  125.770 1.00 121.08 ? 469 ALA C C   1 
ATOM 217  O O   . ALA A 1 29  ? 99.699  76.412  125.187 1.00 123.31 ? 469 ALA C O   1 
ATOM 218  C CB  . ALA A 1 29  ? 102.331 77.173  126.952 1.00 119.69 ? 469 ALA C CB  1 
ATOM 219  N N   . ARG A 1 30  ? 100.406 74.699  126.467 1.00 116.39 ? 470 ARG C N   1 
ATOM 220  C CA  . ARG A 1 30  ? 99.058  74.212  126.719 1.00 119.33 ? 470 ARG C CA  1 
ATOM 221  C C   . ARG A 1 30  ? 98.512  75.143  127.792 1.00 124.20 ? 470 ARG C C   1 
ATOM 222  O O   . ARG A 1 30  ? 99.185  75.418  128.789 1.00 125.46 ? 470 ARG C O   1 
ATOM 223  C CB  . ARG A 1 30  ? 99.100  72.790  127.272 1.00 118.31 ? 470 ARG C CB  1 
ATOM 224  C CG  . ARG A 1 30  ? 99.853  71.814  126.393 1.00 116.82 ? 470 ARG C CG  1 
ATOM 225  C CD  . ARG A 1 30  ? 99.233  70.431  126.434 1.00 114.87 ? 470 ARG C CD  1 
ATOM 226  N NE  . ARG A 1 30  ? 99.740  69.584  125.362 1.00 117.47 ? 470 ARG C NE  1 
ATOM 227  C CZ  . ARG A 1 30  ? 99.691  68.260  125.367 1.00 121.42 ? 470 ARG C CZ  1 
ATOM 228  N NH1 . ARG A 1 30  ? 99.158  67.592  126.377 1.00 122.13 ? 470 ARG C NH1 1 
ATOM 229  N NH2 . ARG A 1 30  ? 100.189 67.588  124.334 1.00 123.01 ? 470 ARG C NH2 1 
ATOM 230  N N   . GLU A 1 31  ? 97.292  75.625  127.589 1.00 126.57 ? 471 GLU C N   1 
ATOM 231  C CA  . GLU A 1 31  ? 96.615  76.467  128.566 1.00 123.47 ? 471 GLU C CA  1 
ATOM 232  C C   . GLU A 1 31  ? 95.298  75.817  128.921 1.00 122.84 ? 471 GLU C C   1 
ATOM 233  O O   . GLU A 1 31  ? 94.705  75.141  128.076 1.00 119.78 ? 471 GLU C O   1 
ATOM 234  C CB  . GLU A 1 31  ? 96.422  77.894  128.046 1.00 124.30 ? 471 GLU C CB  1 
ATOM 235  C CG  . GLU A 1 31  ? 97.706  78.715  127.864 1.00 128.87 ? 471 GLU C CG  1 
ATOM 236  C CD  . GLU A 1 31  ? 97.494  80.110  127.277 1.00 131.40 ? 471 GLU C CD  1 
ATOM 237  O OE1 . GLU A 1 31  ? 96.362  80.383  126.827 1.00 133.44 ? 471 GLU C OE1 1 
ATOM 238  O OE2 . GLU A 1 31  ? 98.429  80.937  127.257 1.00 131.07 ? 471 GLU C OE2 1 
ATOM 239  N N   . GLY A 1 32  ? 94.871  75.963  130.171 1.00 134.75 ? 472 GLY C N   1 
ATOM 240  C CA  . GLY A 1 32  ? 93.669  75.307  130.642 1.00 136.92 ? 472 GLY C CA  1 
ATOM 241  C C   . GLY A 1 32  ? 92.361  76.024  130.397 1.00 137.15 ? 472 GLY C C   1 
ATOM 242  O O   . GLY A 1 32  ? 92.184  77.170  130.822 1.00 134.22 ? 472 GLY C O   1 
ATOM 243  N N   . VAL A 1 33  ? 91.431  75.363  129.711 1.00 143.72 ? 473 VAL C N   1 
ATOM 244  C CA  . VAL A 1 33  ? 90.146  75.997  129.447 1.00 139.91 ? 473 VAL C CA  1 
ATOM 245  C C   . VAL A 1 33  ? 89.182  75.769  130.604 1.00 140.97 ? 473 VAL C C   1 
ATOM 246  O O   . VAL A 1 33  ? 88.408  76.663  130.957 1.00 143.35 ? 473 VAL C O   1 
ATOM 247  C CB  . VAL A 1 33  ? 89.569  75.519  128.099 1.00 139.26 ? 473 VAL C CB  1 
ATOM 248  C CG1 . VAL A 1 33  ? 88.857  74.182  128.228 1.00 138.96 ? 473 VAL C CG1 1 
ATOM 249  C CG2 . VAL A 1 33  ? 88.623  76.565  127.538 1.00 143.71 ? 473 VAL C CG2 1 
ATOM 250  N N   . ALA A 1 34  ? 89.223  74.598  131.237 1.00 155.77 ? 474 ALA C N   1 
ATOM 251  C CA  . ALA A 1 34  ? 88.289  74.346  132.325 1.00 157.32 ? 474 ALA C CA  1 
ATOM 252  C C   . ALA A 1 34  ? 88.836  73.246  133.216 1.00 160.83 ? 474 ALA C C   1 
ATOM 253  O O   . ALA A 1 34  ? 89.675  72.446  132.798 1.00 164.18 ? 474 ALA C O   1 
ATOM 254  C CB  . ALA A 1 34  ? 86.903  73.965  131.795 1.00 156.74 ? 474 ALA C CB  1 
ATOM 255  N N   . THR A 1 35  ? 88.337  73.205  134.450 1.00 157.21 ? 475 THR C N   1 
ATOM 256  C CA  . THR A 1 35  ? 88.686  72.118  135.353 1.00 157.73 ? 475 THR C CA  1 
ATOM 257  C C   . THR A 1 35  ? 87.531  71.874  136.311 1.00 156.36 ? 475 THR C C   1 
ATOM 258  O O   . THR A 1 35  ? 86.776  72.790  136.641 1.00 157.79 ? 475 THR C O   1 
ATOM 259  C CB  . THR A 1 35  ? 89.975  72.414  136.132 1.00 155.63 ? 475 THR C CB  1 
ATOM 260  O OG1 . THR A 1 35  ? 90.255  71.330  137.026 1.00 155.76 ? 475 THR C OG1 1 
ATOM 261  C CG2 . THR A 1 35  ? 89.840  73.698  136.927 1.00 154.55 ? 475 THR C CG2 1 
ATOM 262  N N   . VAL A 1 36  ? 87.385  70.620  136.733 1.00 158.66 ? 476 VAL C N   1 
ATOM 263  C CA  . VAL A 1 36  ? 86.398  70.221  137.727 1.00 157.52 ? 476 VAL C CA  1 
ATOM 264  C C   . VAL A 1 36  ? 87.063  69.383  138.810 1.00 156.92 ? 476 VAL C C   1 
ATOM 265  O O   . VAL A 1 36  ? 87.929  68.548  138.524 1.00 160.45 ? 476 VAL C O   1 
ATOM 266  C CB  . VAL A 1 36  ? 85.196  69.486  137.094 1.00 157.26 ? 476 VAL C CB  1 
ATOM 267  C CG1 . VAL A 1 36  ? 84.599  70.316  135.990 1.00 157.03 ? 476 VAL C CG1 1 
ATOM 268  C CG2 . VAL A 1 36  ? 85.638  68.162  136.502 1.00 156.44 ? 476 VAL C CG2 1 
ATOM 269  N N   . ASP A 1 37  ? 86.828  69.730  140.073 1.00 171.21 ? 477 ASP C N   1 
ATOM 270  C CA  . ASP A 1 37  ? 87.393  69.007  141.236 1.00 173.85 ? 477 ASP C CA  1 
ATOM 271  C C   . ASP A 1 37  ? 86.319  68.098  141.828 1.00 174.05 ? 477 ASP C C   1 
ATOM 272  O O   . ASP A 1 37  ? 85.140  68.360  141.552 1.00 174.30 ? 477 ASP C O   1 
ATOM 273  C CB  . ASP A 1 37  ? 87.922  69.992  142.263 1.00 174.03 ? 477 ASP C CB  1 
ATOM 274  C CG  . ASP A 1 37  ? 88.568  69.374  143.493 1.00 174.80 ? 477 ASP C CG  1 
ATOM 275  O OD1 . ASP A 1 37  ? 89.666  68.796  143.352 1.00 175.61 ? 477 ASP C OD1 1 
ATOM 276  O OD2 . ASP A 1 37  ? 87.959  69.462  144.579 1.00 173.38 ? 477 ASP C OD2 1 
ATOM 277  N N   . LEU A 1 38  ? 86.754  67.060  142.543 1.00 176.54 ? 478 LEU C N   1 
ATOM 278  C CA  . LEU A 1 38  ? 85.818  66.137  143.210 1.00 175.90 ? 478 LEU C CA  1 
ATOM 279  C C   . LEU A 1 38  ? 84.873  66.973  144.068 1.00 176.84 ? 478 LEU C C   1 
ATOM 280  O O   . LEU A 1 38  ? 85.349  67.972  144.628 1.00 176.50 ? 478 LEU C O   1 
ATOM 281  C CB  . LEU A 1 38  ? 86.588  65.120  144.042 1.00 175.57 ? 478 LEU C CB  1 
ATOM 282  C CG  . LEU A 1 38  ? 85.767  63.945  144.577 1.00 174.81 ? 478 LEU C CG  1 
ATOM 283  C CD1 . LEU A 1 38  ? 84.953  63.276  143.487 1.00 174.32 ? 478 LEU C CD1 1 
ATOM 284  C CD2 . LEU A 1 38  ? 86.692  62.946  145.228 1.00 174.37 ? 478 LEU C CD2 1 
ATOM 285  N N   . ASP A 1 39  ? 83.598  66.604  144.118 1.00 181.54 ? 479 ASP C N   1 
ATOM 286  C CA  . ASP A 1 39  ? 82.540  67.322  144.886 1.00 182.19 ? 479 ASP C CA  1 
ATOM 287  C C   . ASP A 1 39  ? 81.900  68.298  143.893 1.00 182.45 ? 479 ASP C C   1 
ATOM 288  O O   . ASP A 1 39  ? 81.038  69.083  144.323 1.00 181.26 ? 479 ASP C O   1 
ATOM 289  C CB  . ASP A 1 39  ? 82.998  67.845  146.248 1.00 181.63 ? 479 ASP C CB  1 
ATOM 290  C CG  . ASP A 1 39  ? 83.378  69.314  146.382 1.00 181.59 ? 479 ASP C CG  1 
ATOM 291  O OD1 . ASP A 1 39  ? 84.553  69.591  146.694 1.00 181.10 ? 479 ASP C OD1 1 
ATOM 292  O OD2 . ASP A 1 39  ? 82.485  70.171  146.251 1.00 181.94 ? 479 ASP C OD2 1 
ATOM 293  N N   . GLY A 1 40  ? 82.248  68.222  142.603 1.00 175.03 ? 480 GLY C N   1 
ATOM 294  C CA  . GLY A 1 40  ? 81.593  69.032  141.598 1.00 172.52 ? 480 GLY C CA  1 
ATOM 295  C C   . GLY A 1 40  ? 82.068  70.463  141.481 1.00 171.85 ? 480 GLY C C   1 
ATOM 296  O O   . GLY A 1 40  ? 81.551  71.196  140.629 1.00 169.35 ? 480 GLY C O   1 
ATOM 297  N N   . SER A 1 41  ? 83.021  70.890  142.306 1.00 169.94 ? 481 SER C N   1 
ATOM 298  C CA  . SER A 1 41  ? 83.560  72.239  142.182 1.00 168.23 ? 481 SER C CA  1 
ATOM 299  C C   . SER A 1 41  ? 84.221  72.413  140.821 1.00 169.06 ? 481 SER C C   1 
ATOM 300  O O   . SER A 1 41  ? 84.964  71.541  140.363 1.00 172.98 ? 481 SER C O   1 
ATOM 301  C CB  . SER A 1 41  ? 84.562  72.511  143.302 1.00 168.26 ? 481 SER C CB  1 
ATOM 302  O OG  . SER A 1 41  ? 84.069  72.051  144.547 1.00 168.28 ? 481 SER C OG  1 
ATOM 303  N N   . THR A 1 42  ? 83.949  73.543  140.172 1.00 151.54 ? 482 THR C N   1 
ATOM 304  C CA  . THR A 1 42  ? 84.422  73.786  138.818 1.00 153.62 ? 482 THR C CA  1 
ATOM 305  C C   . THR A 1 42  ? 85.027  75.178  138.709 1.00 153.29 ? 482 THR C C   1 
ATOM 306  O O   . THR A 1 42  ? 84.593  76.120  139.378 1.00 152.49 ? 482 THR C O   1 
ATOM 307  C CB  . THR A 1 42  ? 83.291  73.635  137.794 1.00 153.75 ? 482 THR C CB  1 
ATOM 308  O OG1 . THR A 1 42  ? 83.721  74.147  136.528 1.00 154.73 ? 482 THR C OG1 1 
ATOM 309  C CG2 . THR A 1 42  ? 82.056  74.395  138.251 1.00 153.27 ? 482 THR C CG2 1 
ATOM 310  N N   . ILE A 1 43  ? 86.043  75.294  137.855 1.00 146.24 ? 483 ILE C N   1 
ATOM 311  C CA  . ILE A 1 43  ? 86.739  76.549  137.600 1.00 142.11 ? 483 ILE C CA  1 
ATOM 312  C C   . ILE A 1 43  ? 86.877  76.730  136.095 1.00 143.61 ? 483 ILE C C   1 
ATOM 313  O O   . ILE A 1 43  ? 87.236  75.786  135.378 1.00 146.63 ? 483 ILE C O   1 
ATOM 314  C CB  . ILE A 1 43  ? 88.124  76.590  138.274 1.00 139.87 ? 483 ILE C CB  1 
ATOM 315  C CG1 . ILE A 1 43  ? 88.011  76.279  139.767 1.00 141.20 ? 483 ILE C CG1 1 
ATOM 316  C CG2 . ILE A 1 43  ? 88.786  77.942  138.056 1.00 137.65 ? 483 ILE C CG2 1 
ATOM 317  C CD1 . ILE A 1 43  ? 89.312  76.425  140.520 1.00 142.17 ? 483 ILE C CD1 1 
ATOM 318  N N   . TYR A 1 44  ? 86.590  77.940  135.621 1.00 151.26 ? 484 TYR C N   1 
ATOM 319  C CA  . TYR A 1 44  ? 86.757  78.323  134.230 1.00 152.22 ? 484 TYR C CA  1 
ATOM 320  C C   . TYR A 1 44  ? 87.694  79.521  134.154 1.00 152.02 ? 484 TYR C C   1 
ATOM 321  O O   . TYR A 1 44  ? 87.863  80.263  135.125 1.00 153.48 ? 484 TYR C O   1 
ATOM 322  C CB  . TYR A 1 44  ? 85.412  78.670  133.577 1.00 152.01 ? 484 TYR C CB  1 
ATOM 323  C CG  . TYR A 1 44  ? 84.415  77.533  133.559 1.00 153.16 ? 484 TYR C CG  1 
ATOM 324  C CD1 . TYR A 1 44  ? 83.562  77.317  134.632 1.00 151.95 ? 484 TYR C CD1 1 
ATOM 325  C CD2 . TYR A 1 44  ? 84.323  76.680  132.468 1.00 153.12 ? 484 TYR C CD2 1 
ATOM 326  C CE1 . TYR A 1 44  ? 82.648  76.285  134.620 1.00 152.46 ? 484 TYR C CE1 1 
ATOM 327  C CE2 . TYR A 1 44  ? 83.412  75.643  132.448 1.00 152.19 ? 484 TYR C CE2 1 
ATOM 328  C CZ  . TYR A 1 44  ? 82.578  75.449  133.527 1.00 152.69 ? 484 TYR C CZ  1 
ATOM 329  O OH  . TYR A 1 44  ? 81.667  74.419  133.516 1.00 152.02 ? 484 TYR C OH  1 
ATOM 330  N N   . ALA A 1 45  ? 88.308  79.707  132.990 1.00 149.46 ? 485 ALA C N   1 
ATOM 331  C CA  . ALA A 1 45  ? 89.227  80.816  132.789 1.00 149.22 ? 485 ALA C CA  1 
ATOM 332  C C   . ALA A 1 45  ? 88.464  82.026  132.249 1.00 148.73 ? 485 ALA C C   1 
ATOM 333  O O   . ALA A 1 45  ? 87.230  82.058  132.239 1.00 149.64 ? 485 ALA C O   1 
ATOM 334  C CB  . ALA A 1 45  ? 90.374  80.399  131.871 1.00 151.21 ? 485 ALA C CB  1 
ATOM 335  N N   . ASP A 1 46  ? 89.202  83.039  131.789 1.00 159.54 ? 486 ASP C N   1 
ATOM 336  C CA  . ASP A 1 46  ? 88.585  84.315  131.437 1.00 162.56 ? 486 ASP C CA  1 
ATOM 337  C C   . ASP A 1 46  ? 87.681  84.196  130.214 1.00 163.55 ? 486 ASP C C   1 
ATOM 338  O O   . ASP A 1 46  ? 86.558  84.713  130.217 1.00 166.22 ? 486 ASP C O   1 
ATOM 339  C CB  . ASP A 1 46  ? 89.668  85.366  131.204 1.00 162.97 ? 486 ASP C CB  1 
ATOM 340  C CG  . ASP A 1 46  ? 90.578  85.534  132.403 1.00 163.71 ? 486 ASP C CG  1 
ATOM 341  O OD1 . ASP A 1 46  ? 91.323  84.584  132.721 1.00 163.12 ? 486 ASP C OD1 1 
ATOM 342  O OD2 . ASP A 1 46  ? 90.543  86.613  133.030 1.00 165.43 ? 486 ASP C OD2 1 
ATOM 343  N N   . SER A 1 47  ? 88.145  83.520  129.163 1.00 157.76 ? 487 SER C N   1 
ATOM 344  C CA  . SER A 1 47  ? 87.406  83.422  127.910 1.00 159.17 ? 487 SER C CA  1 
ATOM 345  C C   . SER A 1 47  ? 86.600  82.132  127.815 1.00 159.91 ? 487 SER C C   1 
ATOM 346  O O   . SER A 1 47  ? 86.439  81.576  126.724 1.00 159.14 ? 487 SER C O   1 
ATOM 347  C CB  . SER A 1 47  ? 88.360  83.540  126.722 1.00 157.40 ? 487 SER C CB  1 
ATOM 348  O OG  . SER A 1 47  ? 88.751  82.261  126.257 1.00 158.93 ? 487 SER C OG  1 
ATOM 349  N N   . VAL A 1 48  ? 86.105  81.637  128.952 1.00 169.99 ? 488 VAL C N   1 
ATOM 350  C CA  . VAL A 1 48  ? 85.429  80.309  128.972 1.00 170.67 ? 488 VAL C CA  1 
ATOM 351  C C   . VAL A 1 48  ? 83.997  80.412  129.512 1.00 172.65 ? 488 VAL C C   1 
ATOM 352  O O   . VAL A 1 48  ? 83.160  79.655  129.006 1.00 174.43 ? 488 VAL C O   1 
ATOM 353  C CB  . VAL A 1 48  ? 86.295  79.358  129.810 1.00 169.67 ? 488 VAL C CB  1 
ATOM 354  C CG1 . VAL A 1 48  ? 85.840  77.923  129.615 1.00 168.55 ? 488 VAL C CG1 1 
ATOM 355  C CG2 . VAL A 1 48  ? 87.769  79.522  129.464 1.00 169.21 ? 488 VAL C CG2 1 
ATOM 356  N N   . LYS A 1 49  ? 83.717  81.263  130.501 1.00 169.14 ? 489 LYS C N   1 
ATOM 357  C CA  . LYS A 1 49  ? 82.378  81.311  131.077 1.00 166.40 ? 489 LYS C CA  1 
ATOM 358  C C   . LYS A 1 49  ? 81.356  81.785  130.051 1.00 166.73 ? 489 LYS C C   1 
ATOM 359  O O   . LYS A 1 49  ? 81.619  82.690  129.254 1.00 166.02 ? 489 LYS C O   1 
ATOM 360  C CB  . LYS A 1 49  ? 82.357  82.221  132.306 1.00 166.30 ? 489 LYS C CB  1 
ATOM 361  C CG  . LYS A 1 49  ? 82.664  83.678  132.016 1.00 167.82 ? 489 LYS C CG  1 
ATOM 362  C CD  . LYS A 1 49  ? 83.154  84.389  133.263 1.00 168.57 ? 489 LYS C CD  1 
ATOM 363  C CE  . LYS A 1 49  ? 84.544  83.917  133.643 1.00 168.06 ? 489 LYS C CE  1 
ATOM 364  N NZ  . LYS A 1 49  ? 85.480  84.018  132.494 1.00 168.11 ? 489 LYS C NZ  1 
ATOM 365  N N   . GLY A 1 50  ? 80.188  81.146  130.063 1.00 175.20 ? 490 GLY C N   1 
ATOM 366  C CA  . GLY A 1 50  ? 79.106  81.481  129.168 1.00 178.19 ? 490 GLY C CA  1 
ATOM 367  C C   . GLY A 1 50  ? 79.131  80.760  127.838 1.00 177.53 ? 490 GLY C C   1 
ATOM 368  O O   . GLY A 1 50  ? 78.105  80.721  127.150 1.00 179.60 ? 490 GLY C O   1 
ATOM 369  N N   . ARG A 1 51  ? 80.295  80.216  127.447 1.00 171.36 ? 491 ARG C N   1 
ATOM 370  C CA  . ARG A 1 51  ? 80.453  79.522  126.139 1.00 170.66 ? 491 ARG C CA  1 
ATOM 371  C C   . ARG A 1 51  ? 81.086  78.128  126.326 1.00 173.48 ? 491 ARG C C   1 
ATOM 372  O O   . ARG A 1 51  ? 81.307  77.474  125.301 1.00 174.85 ? 491 ARG C O   1 
ATOM 373  C CB  . ARG A 1 51  ? 81.295  80.333  125.144 1.00 170.06 ? 491 ARG C CB  1 
ATOM 374  C CG  . ARG A 1 51  ? 82.555  80.999  125.673 1.00 169.76 ? 491 ARG C CG  1 
ATOM 375  C CD  . ARG A 1 51  ? 82.491  82.495  125.480 1.00 170.82 ? 491 ARG C CD  1 
ATOM 376  N NE  . ARG A 1 51  ? 81.692  83.115  126.540 1.00 172.48 ? 491 ARG C NE  1 
ATOM 377  C CZ  . ARG A 1 51  ? 80.453  83.580  126.444 1.00 174.16 ? 491 ARG C CZ  1 
ATOM 378  N NH1 . ARG A 1 51  ? 80.019  84.445  127.339 1.00 173.43 ? 491 ARG C NH1 1 
ATOM 379  N NH2 . ARG A 1 51  ? 79.636  83.172  125.491 1.00 174.93 ? 491 ARG C NH2 1 
ATOM 380  N N   . PHE A 1 52  ? 81.372  77.676  127.554 1.00 173.35 ? 492 PHE C N   1 
ATOM 381  C CA  . PHE A 1 52  ? 81.929  76.318  127.777 1.00 171.46 ? 492 PHE C CA  1 
ATOM 382  C C   . PHE A 1 52  ? 81.503  75.844  129.139 1.00 170.69 ? 492 PHE C C   1 
ATOM 383  O O   . PHE A 1 52  ? 81.683  76.630  130.096 1.00 170.03 ? 492 PHE C O   1 
ATOM 384  C CB  . PHE A 1 52  ? 83.452  76.341  127.651 1.00 171.62 ? 492 PHE C CB  1 
ATOM 385  C CG  . PHE A 1 52  ? 83.938  76.773  126.277 1.00 172.83 ? 492 PHE C CG  1 
ATOM 386  C CD1 . PHE A 1 52  ? 84.409  78.061  126.066 1.00 171.53 ? 492 PHE C CD1 1 
ATOM 387  C CD2 . PHE A 1 52  ? 83.896  75.899  125.200 1.00 171.58 ? 492 PHE C CD2 1 
ATOM 388  C CE1 . PHE A 1 52  ? 84.842  78.458  124.813 1.00 170.87 ? 492 PHE C CE1 1 
ATOM 389  C CE2 . PHE A 1 52  ? 84.330  76.302  123.948 1.00 170.54 ? 492 PHE C CE2 1 
ATOM 390  C CZ  . PHE A 1 52  ? 84.801  77.580  123.758 1.00 170.62 ? 492 PHE C CZ  1 
ATOM 391  N N   . THR A 1 53  ? 80.932  74.639  129.233 1.00 173.59 ? 493 THR C N   1 
ATOM 392  C CA  . THR A 1 53  ? 80.581  74.059  130.522 1.00 173.98 ? 493 THR C CA  1 
ATOM 393  C C   . THR A 1 53  ? 81.055  72.615  130.578 1.00 174.64 ? 493 THR C C   1 
ATOM 394  O O   . THR A 1 53  ? 81.098  71.917  129.563 1.00 175.56 ? 493 THR C O   1 
ATOM 395  C CB  . THR A 1 53  ? 79.072  74.140  130.809 1.00 176.19 ? 493 THR C CB  1 
ATOM 396  O OG1 . THR A 1 53  ? 78.799  73.583  132.101 1.00 175.58 ? 493 THR C OG1 1 
ATOM 397  C CG2 . THR A 1 53  ? 78.279  73.390  129.764 1.00 175.70 ? 493 THR C CG2 1 
ATOM 398  N N   . ILE A 1 54  ? 81.482  72.225  131.781 1.00 175.73 ? 494 ILE C N   1 
ATOM 399  C CA  . ILE A 1 54  ? 82.106  70.898  131.995 1.00 177.13 ? 494 ILE C CA  1 
ATOM 400  C C   . ILE A 1 54  ? 81.436  70.241  133.196 1.00 175.83 ? 494 ILE C C   1 
ATOM 401  O O   . ILE A 1 54  ? 81.042  70.979  134.114 1.00 175.86 ? 494 ILE C O   1 
ATOM 402  C CB  . ILE A 1 54  ? 83.621  71.058  132.220 1.00 178.72 ? 494 ILE C CB  1 
ATOM 403  C CG1 . ILE A 1 54  ? 84.290  69.741  132.610 1.00 178.81 ? 494 ILE C CG1 1 
ATOM 404  C CG2 . ILE A 1 54  ? 83.936  72.167  133.228 1.00 175.31 ? 494 ILE C CG2 1 
ATOM 405  C CD1 . ILE A 1 54  ? 85.802  69.823  132.669 1.00 178.24 ? 494 ILE C CD1 1 
ATOM 406  N N   . SER A 1 55  ? 81.294  68.921  133.171 1.00 180.11 ? 495 SER C N   1 
ATOM 407  C CA  . SER A 1 55  ? 80.753  68.178  134.301 1.00 180.50 ? 495 SER C CA  1 
ATOM 408  C C   . SER A 1 55  ? 81.289  66.754  134.289 1.00 181.62 ? 495 SER C C   1 
ATOM 409  O O   . SER A 1 55  ? 81.401  66.136  133.227 1.00 181.91 ? 495 SER C O   1 
ATOM 410  C CB  . SER A 1 55  ? 79.222  68.157  134.270 1.00 179.88 ? 495 SER C CB  1 
ATOM 411  O OG  . SER A 1 55  ? 78.750  67.233  133.304 1.00 179.50 ? 495 SER C OG  1 
ATOM 412  N N   . GLN A 1 56  ? 81.607  66.233  135.475 1.00 193.58 ? 496 GLN C N   1 
ATOM 413  C CA  . GLN A 1 56  ? 82.062  64.859  135.600 1.00 194.35 ? 496 GLN C CA  1 
ATOM 414  C C   . GLN A 1 56  ? 80.823  64.019  135.900 1.00 194.05 ? 496 GLN C C   1 
ATOM 415  O O   . GLN A 1 56  ? 79.696  64.517  135.949 1.00 192.44 ? 496 GLN C O   1 
ATOM 416  C CB  . GLN A 1 56  ? 83.055  64.696  136.751 1.00 193.83 ? 496 GLN C CB  1 
ATOM 417  C CG  . GLN A 1 56  ? 82.666  65.427  138.030 1.00 193.72 ? 496 GLN C CG  1 
ATOM 418  C CD  . GLN A 1 56  ? 83.804  65.515  139.033 1.00 192.92 ? 496 GLN C CD  1 
ATOM 419  O OE1 . GLN A 1 56  ? 84.583  66.467  139.017 1.00 190.20 ? 496 GLN C OE1 1 
ATOM 420  N NE2 . GLN A 1 56  ? 83.920  64.517  139.891 1.00 193.49 ? 496 GLN C NE2 1 
ATOM 421  N N   . ASP A 1 57  ? 81.040  62.721  136.102 1.00 212.08 ? 497 ASP C N   1 
ATOM 422  C CA  . ASP A 1 57  ? 80.145  61.859  136.851 1.00 211.91 ? 497 ASP C CA  1 
ATOM 423  C C   . ASP A 1 57  ? 80.920  60.582  137.095 1.00 212.49 ? 497 ASP C C   1 
ATOM 424  O O   . ASP A 1 57  ? 81.694  60.158  136.227 1.00 213.86 ? 497 ASP C O   1 
ATOM 425  C CB  . ASP A 1 57  ? 78.786  61.612  136.179 1.00 210.01 ? 497 ASP C CB  1 
ATOM 426  C CG  . ASP A 1 57  ? 78.903  60.849  134.879 1.00 210.94 ? 497 ASP C CG  1 
ATOM 427  O OD1 . ASP A 1 57  ? 80.014  60.364  134.585 1.00 211.77 ? 497 ASP C OD1 1 
ATOM 428  O OD2 . ASP A 1 57  ? 77.898  60.732  134.152 1.00 210.77 ? 497 ASP C OD2 1 
ATOM 429  N N   . ASN A 1 58  ? 80.775  60.017  138.293 1.00 213.87 ? 498 ASN C N   1 
ATOM 430  C CA  . ASN A 1 58  ? 81.451  58.784  138.668 1.00 214.42 ? 498 ASN C CA  1 
ATOM 431  C C   . ASN A 1 58  ? 80.668  57.518  138.352 1.00 215.27 ? 498 ASN C C   1 
ATOM 432  O O   . ASN A 1 58  ? 81.176  56.418  138.598 1.00 215.73 ? 498 ASN C O   1 
ATOM 433  C CB  . ASN A 1 58  ? 81.649  58.897  140.185 1.00 213.36 ? 498 ASN C CB  1 
ATOM 434  N N   . ALA A 1 59  ? 79.448  57.646  137.825 1.00 217.75 ? 499 ALA C N   1 
ATOM 435  C CA  . ALA A 1 59  ? 78.674  56.467  137.449 1.00 217.39 ? 499 ALA C CA  1 
ATOM 436  C C   . ALA A 1 59  ? 79.353  55.487  136.503 1.00 217.68 ? 499 ALA C C   1 
ATOM 437  O O   . ALA A 1 59  ? 79.274  54.266  136.689 1.00 218.29 ? 499 ALA C O   1 
ATOM 438  C CB  . ALA A 1 59  ? 77.269  56.881  137.009 1.00 215.78 ? 499 ALA C CB  1 
ATOM 439  N N   . LYS A 1 60  ? 80.036  56.098  135.519 1.00 213.69 ? 500 LYS C N   1 
ATOM 440  C CA  . LYS A 1 60  ? 80.800  55.372  134.485 1.00 213.00 ? 500 LYS C CA  1 
ATOM 441  C C   . LYS A 1 60  ? 82.094  56.161  134.269 1.00 212.99 ? 500 LYS C C   1 
ATOM 442  O O   . LYS A 1 60  ? 82.459  56.022  133.134 1.00 213.66 ? 500 LYS C O   1 
ATOM 443  C CB  . LYS A 1 60  ? 79.971  55.307  133.195 1.00 212.75 ? 500 LYS C CB  1 
ATOM 444  N N   . ASN A 1 61  ? 82.783  56.737  135.285 1.00 209.74 ? 501 ASN C N   1 
ATOM 445  C CA  . ASN A 1 61  ? 83.944  57.630  135.366 1.00 209.99 ? 501 ASN C CA  1 
ATOM 446  C C   . ASN A 1 61  ? 84.370  58.455  134.155 1.00 210.26 ? 501 ASN C C   1 
ATOM 447  O O   . ASN A 1 61  ? 85.494  58.323  133.660 1.00 210.18 ? 501 ASN C O   1 
ATOM 448  C CB  . ASN A 1 61  ? 85.030  56.598  135.734 1.00 208.85 ? 501 ASN C CB  1 
ATOM 449  C CG  . ASN A 1 61  ? 85.290  55.543  134.658 1.00 208.84 ? 501 ASN C CG  1 
ATOM 450  O OD1 . ASN A 1 61  ? 85.206  55.795  133.463 1.00 209.67 ? 501 ASN C OD1 1 
ATOM 451  N ND2 . ASN A 1 61  ? 85.606  54.334  135.106 1.00 207.78 ? 501 ASN C ND2 1 
ATOM 452  N N   . THR A 1 62  ? 83.472  59.315  133.678 1.00 200.61 ? 502 THR C N   1 
ATOM 453  C CA  . THR A 1 62  ? 83.697  60.092  132.467 1.00 198.40 ? 502 THR C CA  1 
ATOM 454  C C   . THR A 1 62  ? 83.474  61.590  132.586 1.00 198.30 ? 502 THR C C   1 
ATOM 455  O O   . THR A 1 62  ? 82.522  62.032  133.234 1.00 199.62 ? 502 THR C O   1 
ATOM 456  C CB  . THR A 1 62  ? 82.905  59.506  131.283 1.00 197.09 ? 502 THR C CB  1 
ATOM 457  O OG1 . THR A 1 62  ? 83.302  58.147  131.060 1.00 197.99 ? 502 THR C OG1 1 
ATOM 458  C CG2 . THR A 1 62  ? 83.134  60.314  130.016 1.00 196.20 ? 502 THR C CG2 1 
ATOM 459  N N   . LEU A 1 63  ? 84.326  62.401  131.954 1.00 182.43 ? 503 LEU C N   1 
ATOM 460  C CA  . LEU A 1 63  ? 84.162  63.875  131.903 1.00 182.97 ? 503 LEU C CA  1 
ATOM 461  C C   . LEU A 1 63  ? 83.419  64.251  130.619 1.00 182.54 ? 503 LEU C C   1 
ATOM 462  O O   . LEU A 1 63  ? 83.437  63.448  129.691 1.00 181.40 ? 503 LEU C O   1 
ATOM 463  C CB  . LEU A 1 63  ? 85.544  64.517  131.940 1.00 180.26 ? 503 LEU C CB  1 
ATOM 464  C CG  . LEU A 1 63  ? 85.649  65.951  132.465 1.00 178.65 ? 503 LEU C CG  1 
ATOM 465  C CD1 . LEU A 1 63  ? 84.962  66.213  133.782 1.00 177.65 ? 503 LEU C CD1 1 
ATOM 466  C CD2 . LEU A 1 63  ? 87.126  66.264  132.581 1.00 181.26 ? 503 LEU C CD2 1 
ATOM 467  N N   . TYR A 1 64  ? 82.736  65.389  130.590 1.00 188.29 ? 504 TYR C N   1 
ATOM 468  C CA  . TYR A 1 64  ? 82.045  65.887  129.415 1.00 187.02 ? 504 TYR C CA  1 
ATOM 469  C C   . TYR A 1 64  ? 82.051  67.407  129.427 1.00 186.57 ? 504 TYR C C   1 
ATOM 470  O O   . TYR A 1 64  ? 82.036  68.047  130.483 1.00 186.28 ? 504 TYR C O   1 
ATOM 471  C CB  . TYR A 1 64  ? 80.624  65.380  129.119 1.00 186.91 ? 504 TYR C CB  1 
ATOM 472  C CG  . TYR A 1 64  ? 80.331  63.985  129.626 1.00 187.62 ? 504 TYR C CG  1 
ATOM 473  C CD1 . TYR A 1 64  ? 80.010  63.761  130.958 1.00 187.48 ? 504 TYR C CD1 1 
ATOM 474  C CD2 . TYR A 1 64  ? 80.386  62.891  128.773 1.00 187.36 ? 504 TYR C CD2 1 
ATOM 475  C CE1 . TYR A 1 64  ? 79.740  62.493  131.422 1.00 187.91 ? 504 TYR C CE1 1 
ATOM 476  C CE2 . TYR A 1 64  ? 80.118  61.615  129.231 1.00 188.26 ? 504 TYR C CE2 1 
ATOM 477  C CZ  . TYR A 1 64  ? 79.798  61.422  130.557 1.00 189.02 ? 504 TYR C CZ  1 
ATOM 478  O OH  . TYR A 1 64  ? 79.532  60.153  131.018 1.00 189.97 ? 504 TYR C OH  1 
ATOM 479  N N   . LEU A 1 65  ? 82.126  67.996  128.227 1.00 180.62 ? 505 LEU C N   1 
ATOM 480  C CA  . LEU A 1 65  ? 82.208  69.470  128.119 1.00 181.57 ? 505 LEU C CA  1 
ATOM 481  C C   . LEU A 1 65  ? 81.373  70.036  126.949 1.00 183.58 ? 505 LEU C C   1 
ATOM 482  O O   . LEU A 1 65  ? 81.871  69.987  125.804 1.00 181.83 ? 505 LEU C O   1 
ATOM 483  C CB  . LEU A 1 65  ? 83.690  69.818  128.018 1.00 178.61 ? 505 LEU C CB  1 
ATOM 484  C CG  . LEU A 1 65  ? 84.073  71.252  128.388 1.00 179.03 ? 505 LEU C CG  1 
ATOM 485  C CD1 . LEU A 1 65  ? 85.505  71.309  128.860 1.00 178.50 ? 505 LEU C CD1 1 
ATOM 486  C CD2 . LEU A 1 65  ? 83.847  72.215  127.244 1.00 179.41 ? 505 LEU C CD2 1 
ATOM 487  N N   . GLN A 1 66  ? 80.160  70.560  127.201 1.00 190.84 ? 506 GLN C N   1 
ATOM 488  C CA  . GLN A 1 66  ? 79.373  71.273  126.204 1.00 189.62 ? 506 GLN C CA  1 
ATOM 489  C C   . GLN A 1 66  ? 80.145  72.514  125.787 1.00 187.81 ? 506 GLN C C   1 
ATOM 490  O O   . GLN A 1 66  ? 80.547  73.313  126.643 1.00 185.31 ? 506 GLN C O   1 
ATOM 491  C CB  . GLN A 1 66  ? 78.009  71.683  126.760 1.00 188.85 ? 506 GLN C CB  1 
ATOM 492  C CG  . GLN A 1 66  ? 76.805  71.425  125.864 1.00 189.25 ? 506 GLN C CG  1 
ATOM 493  C CD  . GLN A 1 66  ? 76.827  70.073  125.206 1.00 189.62 ? 506 GLN C CD  1 
ATOM 494  O OE1 . GLN A 1 66  ? 76.826  69.053  125.880 1.00 189.30 ? 506 GLN C OE1 1 
ATOM 495  N NE2 . GLN A 1 66  ? 76.830  70.055  123.880 1.00 188.89 ? 506 GLN C NE2 1 
ATOM 496  N N   . MET A 1 67  ? 80.326  72.657  124.472 1.00 187.76 ? 507 MET C N   1 
ATOM 497  C CA  . MET A 1 67  ? 80.954  73.885  123.928 1.00 188.28 ? 507 MET C CA  1 
ATOM 498  C C   . MET A 1 67  ? 79.914  74.527  123.008 1.00 191.37 ? 507 MET C C   1 
ATOM 499  O O   . MET A 1 67  ? 79.198  73.776  122.319 1.00 191.91 ? 507 MET C O   1 
ATOM 500  C CB  . MET A 1 67  ? 82.224  73.566  123.135 1.00 187.55 ? 507 MET C CB  1 
ATOM 501  C CG  . MET A 1 67  ? 81.972  72.793  121.854 1.00 188.05 ? 507 MET C CG  1 
ATOM 502  S SD  . MET A 1 67  ? 83.459  72.574  120.842 1.00 188.62 ? 507 MET C SD  1 
ATOM 503  C CE  . MET A 1 67  ? 83.590  74.191  120.081 1.00 188.27 ? 507 MET C CE  1 
ATOM 504  N N   . ASN A 1 68  ? 79.809  75.854  123.022 1.00 191.78 ? 508 ASN C N   1 
ATOM 505  C CA  . ASN A 1 68  ? 78.839  76.567  122.203 1.00 189.24 ? 508 ASN C CA  1 
ATOM 506  C C   . ASN A 1 68  ? 79.332  77.995  122.010 1.00 188.41 ? 508 ASN C C   1 
ATOM 507  O O   . ASN A 1 68  ? 80.358  78.398  122.565 1.00 188.79 ? 508 ASN C O   1 
ATOM 508  C CB  . ASN A 1 68  ? 77.445  76.536  122.836 1.00 187.94 ? 508 ASN C CB  1 
ATOM 509  C CG  . ASN A 1 68  ? 77.484  76.710  124.340 1.00 187.59 ? 508 ASN C CG  1 
ATOM 510  O OD1 . ASN A 1 68  ? 78.071  77.662  124.850 1.00 186.85 ? 508 ASN C OD1 1 
ATOM 511  N ND2 . ASN A 1 68  ? 76.858  75.787  125.059 1.00 186.88 ? 508 ASN C ND2 1 
ATOM 512  N N   . SER A 1 69  ? 78.579  78.764  121.220 1.00 184.98 ? 509 SER C N   1 
ATOM 513  C CA  . SER A 1 69  ? 78.953  80.126  120.842 1.00 185.08 ? 509 SER C CA  1 
ATOM 514  C C   . SER A 1 69  ? 80.340  80.136  120.197 1.00 184.79 ? 509 SER C C   1 
ATOM 515  O O   . SER A 1 69  ? 81.297  80.713  120.715 1.00 184.17 ? 509 SER C O   1 
ATOM 516  C CB  . SER A 1 69  ? 78.890  81.073  122.045 1.00 183.99 ? 509 SER C CB  1 
ATOM 517  O OG  . SER A 1 69  ? 77.623  81.012  122.677 1.00 183.62 ? 509 SER C OG  1 
ATOM 518  N N   . LEU A 1 70  ? 80.441  79.421  119.078 1.00 192.23 ? 510 LEU C N   1 
ATOM 519  C CA  . LEU A 1 70  ? 81.740  79.176  118.410 1.00 191.62 ? 510 LEU C CA  1 
ATOM 520  C C   . LEU A 1 70  ? 82.378  80.426  117.811 1.00 192.79 ? 510 LEU C C   1 
ATOM 521  O O   . LEU A 1 70  ? 81.749  80.996  116.910 1.00 194.95 ? 510 LEU C O   1 
ATOM 522  C CB  . LEU A 1 70  ? 81.439  78.159  117.314 1.00 192.60 ? 510 LEU C CB  1 
ATOM 523  C CG  . LEU A 1 70  ? 81.289  76.703  117.759 1.00 192.98 ? 510 LEU C CG  1 
ATOM 524  C CD1 . LEU A 1 70  ? 80.097  76.468  118.671 1.00 191.66 ? 510 LEU C CD1 1 
ATOM 525  C CD2 . LEU A 1 70  ? 81.193  75.799  116.557 1.00 193.32 ? 510 LEU C CD2 1 
ATOM 526  N N   . LYS A 1 71  ? 83.640  80.690  118.132 1.00 188.13 ? 511 LYS C N   1 
ATOM 527  C CA  . LYS A 1 71  ? 84.400  81.835  117.664 1.00 188.28 ? 511 LYS C CA  1 
ATOM 528  C C   . LYS A 1 71  ? 85.624  81.351  116.903 1.00 188.17 ? 511 LYS C C   1 
ATOM 529  O O   . LYS A 1 71  ? 86.150  80.271  117.187 1.00 187.10 ? 511 LYS C O   1 
ATOM 530  C CB  . LYS A 1 71  ? 84.836  82.734  118.830 1.00 186.56 ? 511 LYS C CB  1 
ATOM 531  C CG  . LYS A 1 71  ? 83.692  83.422  119.555 1.00 187.13 ? 511 LYS C CG  1 
ATOM 532  C CD  . LYS A 1 71  ? 82.844  84.250  118.604 1.00 189.32 ? 511 LYS C CD  1 
ATOM 533  C CE  . LYS A 1 71  ? 81.406  84.344  119.092 1.00 189.07 ? 511 LYS C CE  1 
ATOM 534  N NZ  . LYS A 1 71  ? 80.461  83.627  118.191 1.00 187.69 ? 511 LYS C NZ  1 
ATOM 535  N N   . PRO A 1 72  ? 86.083  82.118  115.912 1.00 190.53 ? 512 PRO C N   1 
ATOM 536  C CA  . PRO A 1 72  ? 87.259  81.682  115.141 1.00 190.08 ? 512 PRO C CA  1 
ATOM 537  C C   . PRO A 1 72  ? 88.560  81.511  115.904 1.00 191.26 ? 512 PRO C C   1 
ATOM 538  O O   . PRO A 1 72  ? 89.347  80.616  115.569 1.00 191.31 ? 512 PRO C O   1 
ATOM 539  C CB  . PRO A 1 72  ? 87.383  82.759  114.053 1.00 190.26 ? 512 PRO C CB  1 
ATOM 540  C CG  . PRO A 1 72  ? 86.036  83.406  113.989 1.00 189.99 ? 512 PRO C CG  1 
ATOM 541  C CD  . PRO A 1 72  ? 85.506  83.364  115.385 1.00 189.93 ? 512 PRO C CD  1 
ATOM 542  N N   . GLU A 1 73  ? 88.822  82.437  116.837 1.00 190.68 ? 513 GLU C N   1 
ATOM 543  C CA  . GLU A 1 73  ? 90.085  82.461  117.614 1.00 189.03 ? 513 GLU C CA  1 
ATOM 544  C C   . GLU A 1 73  ? 90.146  81.261  118.556 1.00 188.16 ? 513 GLU C C   1 
ATOM 545  O O   . GLU A 1 73  ? 91.279  80.839  118.878 1.00 189.85 ? 513 GLU C O   1 
ATOM 546  C CB  . GLU A 1 73  ? 90.108  83.765  118.407 1.00 188.13 ? 513 GLU C CB  1 
ATOM 547  C CG  . GLU A 1 73  ? 91.338  83.930  119.295 1.00 188.48 ? 513 GLU C CG  1 
ATOM 548  C CD  . GLU A 1 73  ? 91.125  83.512  120.739 1.00 189.25 ? 513 GLU C CD  1 
ATOM 549  O OE1 . GLU A 1 73  ? 91.788  82.552  121.183 1.00 188.66 ? 513 GLU C OE1 1 
ATOM 550  O OE2 . GLU A 1 73  ? 90.297  84.150  121.421 1.00 189.40 ? 513 GLU C OE2 1 
ATOM 551  N N   . ASP A 1 74  ? 88.991  80.729  118.971 1.00 180.41 ? 514 ASP C N   1 
ATOM 552  C CA  . ASP A 1 74  ? 88.951  79.610  119.922 1.00 178.09 ? 514 ASP C CA  1 
ATOM 553  C C   . ASP A 1 74  ? 89.033  78.128  119.382 1.00 178.62 ? 514 ASP C C   1 
ATOM 554  O O   . ASP A 1 74  ? 88.379  77.162  119.771 1.00 179.81 ? 514 ASP C O   1 
ATOM 555  C CB  . ASP A 1 74  ? 87.770  79.720  120.879 1.00 178.48 ? 514 ASP C CB  1 
ATOM 556  C CG  . ASP A 1 74  ? 87.923  80.855  121.861 1.00 182.59 ? 514 ASP C CG  1 
ATOM 557  O OD1 . ASP A 1 74  ? 89.049  81.377  121.995 1.00 184.25 ? 514 ASP C OD1 1 
ATOM 558  O OD2 . ASP A 1 74  ? 86.919  81.225  122.499 1.00 184.60 ? 514 ASP C OD2 1 
ATOM 559  N N   . THR A 1 75  ? 89.877  78.060  118.357 1.00 169.74 ? 515 THR C N   1 
ATOM 560  C CA  . THR A 1 75  ? 90.284  76.800  117.747 1.00 169.06 ? 515 THR C CA  1 
ATOM 561  C C   . THR A 1 75  ? 91.723  76.360  117.962 1.00 170.55 ? 515 THR C C   1 
ATOM 562  O O   . THR A 1 75  ? 92.655  77.066  117.562 1.00 171.47 ? 515 THR C O   1 
ATOM 563  C CB  . THR A 1 75  ? 89.955  76.874  116.255 1.00 169.55 ? 515 THR C CB  1 
ATOM 564  O OG1 . THR A 1 75  ? 88.535  76.920  116.081 1.00 172.23 ? 515 THR C OG1 1 
ATOM 565  C CG2 . THR A 1 75  ? 90.506  75.658  115.526 1.00 167.14 ? 515 THR C CG2 1 
ATOM 566  N N   . ALA A 1 76  ? 91.905  75.205  118.591 1.00 160.28 ? 516 ALA C N   1 
ATOM 567  C CA  . ALA A 1 76  ? 93.232  74.783  119.016 1.00 158.73 ? 516 ALA C CA  1 
ATOM 568  C C   . ALA A 1 76  ? 93.238  73.267  119.179 1.00 157.32 ? 516 ALA C C   1 
ATOM 569  O O   . ALA A 1 76  ? 92.333  72.568  118.713 1.00 157.50 ? 516 ALA C O   1 
ATOM 570  C CB  . ALA A 1 76  ? 93.640  75.500  120.306 1.00 156.20 ? 516 ALA C CB  1 
ATOM 571  N N   . MET A 1 77  ? 94.279  72.763  119.832 1.00 152.67 ? 517 MET C N   1 
ATOM 572  C CA  . MET A 1 77  ? 94.457  71.338  120.086 1.00 154.98 ? 517 MET C CA  1 
ATOM 573  C C   . MET A 1 77  ? 93.953  71.030  121.492 1.00 154.56 ? 517 MET C C   1 
ATOM 574  O O   . MET A 1 77  ? 94.575  71.433  122.478 1.00 152.09 ? 517 MET C O   1 
ATOM 575  C CB  . MET A 1 77  ? 95.924  70.963  119.888 1.00 158.11 ? 517 MET C CB  1 
ATOM 576  C CG  . MET A 1 77  ? 96.257  69.482  119.863 1.00 158.42 ? 517 MET C CG  1 
ATOM 577  S SD  . MET A 1 77  ? 95.147  68.455  118.892 1.00 160.96 ? 517 MET C SD  1 
ATOM 578  C CE  . MET A 1 77  ? 94.212  67.693  120.208 1.00 153.06 ? 517 MET C CE  1 
ATOM 579  N N   . TYR A 1 78  ? 92.784  70.396  121.567 1.00 151.28 ? 518 TYR C N   1 
ATOM 580  C CA  . TYR A 1 78  ? 92.161  70.163  122.893 1.00 151.03 ? 518 TYR C CA  1 
ATOM 581  C C   . TYR A 1 78  ? 92.582  68.835  123.460 1.00 149.89 ? 518 TYR C C   1 
ATOM 582  O O   . TYR A 1 78  ? 92.701  67.935  122.703 1.00 149.97 ? 518 TYR C O   1 
ATOM 583  C CB  . TYR A 1 78  ? 90.642  70.276  122.783 1.00 152.02 ? 518 TYR C CB  1 
ATOM 584  C CG  . TYR A 1 78  ? 90.189  71.707  122.559 1.00 153.37 ? 518 TYR C CG  1 
ATOM 585  C CD1 . TYR A 1 78  ? 89.669  72.456  123.601 1.00 151.02 ? 518 TYR C CD1 1 
ATOM 586  C CD2 . TYR A 1 78  ? 90.316  72.313  121.318 1.00 153.50 ? 518 TYR C CD2 1 
ATOM 587  C CE1 . TYR A 1 78  ? 89.261  73.762  123.410 1.00 150.85 ? 518 TYR C CE1 1 
ATOM 588  C CE2 . TYR A 1 78  ? 89.922  73.622  121.115 1.00 152.55 ? 518 TYR C CE2 1 
ATOM 589  C CZ  . TYR A 1 78  ? 89.398  74.349  122.167 1.00 153.74 ? 518 TYR C CZ  1 
ATOM 590  O OH  . TYR A 1 78  ? 89.006  75.639  121.982 1.00 155.83 ? 518 TYR C OH  1 
ATOM 591  N N   . TYR A 1 79  ? 92.973  68.768  124.710 1.00 140.07 ? 519 TYR C N   1 
ATOM 592  C CA  . TYR A 1 79  ? 93.297  67.570  125.465 1.00 142.25 ? 519 TYR C CA  1 
ATOM 593  C C   . TYR A 1 79  ? 92.481  67.507  126.750 1.00 143.81 ? 519 TYR C C   1 
ATOM 594  O O   . TYR A 1 79  ? 92.032  68.528  127.281 1.00 142.83 ? 519 TYR C O   1 
ATOM 595  C CB  . TYR A 1 79  ? 94.787  67.466  125.823 1.00 143.84 ? 519 TYR C CB  1 
ATOM 596  C CG  . TYR A 1 79  ? 95.751  67.586  124.664 1.00 143.48 ? 519 TYR C CG  1 
ATOM 597  C CD1 . TYR A 1 79  ? 96.140  66.467  123.942 1.00 141.45 ? 519 TYR C CD1 1 
ATOM 598  C CD2 . TYR A 1 79  ? 96.297  68.813  124.313 1.00 143.83 ? 519 TYR C CD2 1 
ATOM 599  C CE1 . TYR A 1 79  ? 97.029  66.568  122.893 1.00 143.28 ? 519 TYR C CE1 1 
ATOM 600  C CE2 . TYR A 1 79  ? 97.187  68.924  123.264 1.00 141.79 ? 519 TYR C CE2 1 
ATOM 601  C CZ  . TYR A 1 79  ? 97.549  67.797  122.559 1.00 143.41 ? 519 TYR C CZ  1 
ATOM 602  O OH  . TYR A 1 79  ? 98.437  67.899  121.513 1.00 144.67 ? 519 TYR C OH  1 
ATOM 603  N N   . CYS A 1 80  ? 92.297  66.287  127.248 1.00 160.70 ? 520 CYS C N   1 
ATOM 604  C CA  . CYS A 1 80  ? 91.728  66.046  128.567 1.00 160.36 ? 520 CYS C CA  1 
ATOM 605  C C   . CYS A 1 80  ? 92.838  65.569  129.495 1.00 159.78 ? 520 CYS C C   1 
ATOM 606  O O   . CYS A 1 80  ? 93.631  64.696  129.126 1.00 161.00 ? 520 CYS C O   1 
ATOM 607  C CB  . CYS A 1 80  ? 90.583  65.026  128.505 1.00 161.27 ? 520 CYS C CB  1 
ATOM 608  S SG  . CYS A 1 80  ? 91.061  63.275  128.450 1.00 169.77 ? 520 CYS C SG  1 
ATOM 609  N N   . ALA A 1 81  ? 92.912  66.162  130.682 1.00 144.11 ? 521 ALA C N   1 
ATOM 610  C CA  . ALA A 1 81  ? 93.943  65.847  131.656 1.00 142.01 ? 521 ALA C CA  1 
ATOM 611  C C   . ALA A 1 81  ? 93.302  65.339  132.939 1.00 142.03 ? 521 ALA C C   1 
ATOM 612  O O   . ALA A 1 81  ? 92.215  65.778  133.326 1.00 146.74 ? 521 ALA C O   1 
ATOM 613  C CB  . ALA A 1 81  ? 94.816  67.070  131.959 1.00 142.84 ? 521 ALA C CB  1 
ATOM 614  N N   . SER A 1 82  ? 93.991  64.413  133.598 1.00 150.57 ? 522 SER C N   1 
ATOM 615  C CA  . SER A 1 82  ? 93.490  63.783  134.808 1.00 152.82 ? 522 SER C CA  1 
ATOM 616  C C   . SER A 1 82  ? 94.591  63.707  135.855 1.00 154.29 ? 522 SER C C   1 
ATOM 617  O O   . SER A 1 82  ? 95.781  63.817  135.550 1.00 157.44 ? 522 SER C O   1 
ATOM 618  C CB  . SER A 1 82  ? 92.951  62.377  134.527 1.00 153.84 ? 522 SER C CB  1 
ATOM 619  O OG  . SER A 1 82  ? 93.029  61.574  135.691 1.00 155.34 ? 522 SER C OG  1 
ATOM 620  N N   . ARG A 1 83  ? 94.173  63.530  137.107 1.00 147.60 ? 523 ARG C N   1 
ATOM 621  C CA  . ARG A 1 83  ? 95.116  63.399  138.234 1.00 147.36 ? 523 ARG C CA  1 
ATOM 622  C C   . ARG A 1 83  ? 94.386  62.582  139.297 1.00 149.33 ? 523 ARG C C   1 
ATOM 623  O O   . ARG A 1 83  ? 93.240  62.980  139.589 1.00 153.56 ? 523 ARG C O   1 
ATOM 624  C CB  . ARG A 1 83  ? 95.470  64.821  138.663 1.00 144.11 ? 523 ARG C CB  1 
ATOM 625  C CG  . ARG A 1 83  ? 95.616  65.057  140.156 1.00 144.98 ? 523 ARG C CG  1 
ATOM 626  C CD  . ARG A 1 83  ? 96.514  66.249  140.343 1.00 146.24 ? 523 ARG C CD  1 
ATOM 627  N NE  . ARG A 1 83  ? 97.690  65.879  141.133 1.00 147.38 ? 523 ARG C NE  1 
ATOM 628  C CZ  . ARG A 1 83  ? 97.639  65.667  142.435 1.00 146.70 ? 523 ARG C CZ  1 
ATOM 629  N NH1 . ARG A 1 83  ? 96.542  65.989  143.095 1.00 144.66 ? 523 ARG C NH1 1 
ATOM 630  N NH2 . ARG A 1 83  ? 98.670  65.133  143.062 1.00 147.97 ? 523 ARG C NH2 1 
ATOM 631  N N   . THR A 1 84  ? 94.946  61.454  139.751 1.00 155.78 ? 524 THR C N   1 
ATOM 632  C CA  . THR A 1 84  ? 94.380  60.660  140.836 1.00 156.62 ? 524 THR C CA  1 
ATOM 633  C C   . THR A 1 84  ? 95.227  60.384  142.073 1.00 155.66 ? 524 THR C C   1 
ATOM 634  O O   . THR A 1 84  ? 94.904  59.484  142.853 1.00 155.06 ? 524 THR C O   1 
ATOM 635  C CB  . THR A 1 84  ? 94.012  59.258  140.347 1.00 156.77 ? 524 THR C CB  1 
ATOM 636  O OG1 . THR A 1 84  ? 95.174  58.420  140.376 1.00 156.06 ? 524 THR C OG1 1 
ATOM 637  C CG2 . THR A 1 84  ? 93.468  59.309  138.929 1.00 155.62 ? 524 THR C CG2 1 
ATOM 638  N N   . ARG A 1 85  ? 96.323  61.151  142.259 1.00 144.28 ? 525 ARG C N   1 
ATOM 639  C CA  . ARG A 1 85  ? 97.302  60.974  143.374 1.00 145.99 ? 525 ARG C CA  1 
ATOM 640  C C   . ARG A 1 85  ? 96.882  61.772  144.615 1.00 145.27 ? 525 ARG C C   1 
ATOM 641  O O   . ARG A 1 85  ? 97.608  61.674  145.610 1.00 148.66 ? 525 ARG C O   1 
ATOM 642  C CB  . ARG A 1 85  ? 98.639  61.490  142.823 1.00 147.18 ? 525 ARG C CB  1 
ATOM 643  C CG  . ARG A 1 85  ? 99.951  61.152  143.526 1.00 145.83 ? 525 ARG C CG  1 
ATOM 644  C CD  . ARG A 1 85  ? 100.203 62.053  144.724 1.00 144.93 ? 525 ARG C CD  1 
ATOM 645  N NE  . ARG A 1 85  ? 101.515 62.649  144.979 1.00 144.51 ? 525 ARG C NE  1 
ATOM 646  C CZ  . ARG A 1 85  ? 101.711 63.339  146.096 1.00 142.98 ? 525 ARG C CZ  1 
ATOM 647  N NH1 . ARG A 1 85  ? 100.713 64.029  146.617 1.00 142.53 ? 525 ARG C NH1 1 
ATOM 648  N NH2 . ARG A 1 85  ? 102.883 63.362  146.694 1.00 143.24 ? 525 ARG C NH2 1 
ATOM 649  N N   . ALA A 1 86  ? 95.735  62.450  144.606 1.00 148.29 ? 526 ALA C N   1 
ATOM 650  C CA  . ALA A 1 86  ? 95.241  63.337  145.655 1.00 152.05 ? 526 ALA C CA  1 
ATOM 651  C C   . ALA A 1 86  ? 96.181  64.441  146.123 1.00 153.61 ? 526 ALA C C   1 
ATOM 652  O O   . ALA A 1 86  ? 97.112  64.822  145.406 1.00 154.89 ? 526 ALA C O   1 
ATOM 653  C CB  . ALA A 1 86  ? 94.993  62.334  146.785 1.00 151.27 ? 526 ALA C CB  1 
ATOM 654  N N   . GLY A 1 87  ? 95.938  64.968  147.320 1.00 152.36 ? 527 GLY C N   1 
ATOM 655  C CA  . GLY A 1 87  ? 96.747  66.054  147.830 1.00 150.02 ? 527 GLY C CA  1 
ATOM 656  C C   . GLY A 1 87  ? 96.509  67.386  147.134 1.00 153.85 ? 527 GLY C C   1 
ATOM 657  O O   . GLY A 1 87  ? 95.738  67.499  146.184 1.00 157.84 ? 527 GLY C O   1 
ATOM 658  N N   . VAL A 1 88  ? 97.248  68.400  147.610 1.00 149.35 ? 528 VAL C N   1 
ATOM 659  C CA  . VAL A 1 88  ? 97.253  69.754  146.991 1.00 149.90 ? 528 VAL C CA  1 
ATOM 660  C C   . VAL A 1 88  ? 95.853  70.311  146.738 1.00 153.87 ? 528 VAL C C   1 
ATOM 661  O O   . VAL A 1 88  ? 94.892  69.789  147.338 1.00 154.89 ? 528 VAL C O   1 
ATOM 662  C CB  . VAL A 1 88  ? 98.084  69.649  145.688 1.00 145.21 ? 528 VAL C CB  1 
ATOM 663  C CG1 . VAL A 1 88  ? 97.299  69.395  144.397 1.00 145.09 ? 528 VAL C CG1 1 
ATOM 664  C CG2 . VAL A 1 88  ? 98.971  70.866  145.501 1.00 144.88 ? 528 VAL C CG2 1 
ATOM 665  N N   . THR A 1 89  ? 95.776  71.442  146.051 1.00 156.72 ? 529 THR C N   1 
ATOM 666  C CA  . THR A 1 89  ? 94.531  72.001  145.550 1.00 156.37 ? 529 THR C CA  1 
ATOM 667  C C   . THR A 1 89  ? 94.387  72.007  144.035 1.00 155.35 ? 529 THR C C   1 
ATOM 668  O O   . THR A 1 89  ? 95.380  72.027  143.302 1.00 156.39 ? 529 THR C O   1 
ATOM 669  C CB  . THR A 1 89  ? 94.412  73.435  146.081 1.00 154.51 ? 529 THR C CB  1 
ATOM 670  O OG1 . THR A 1 89  ? 94.954  74.349  145.119 1.00 150.20 ? 529 THR C OG1 1 
ATOM 671  C CG2 . THR A 1 89  ? 95.155  73.584  147.399 1.00 152.42 ? 529 THR C CG2 1 
ATOM 672  N N   . CYS A 1 90  ? 93.139  71.985  143.573 1.00 150.55 ? 530 CYS C N   1 
ATOM 673  C CA  . CYS A 1 90  ? 92.878  72.008  142.142 1.00 150.57 ? 530 CYS C CA  1 
ATOM 674  C C   . CYS A 1 90  ? 93.354  73.322  141.535 1.00 148.75 ? 530 CYS C C   1 
ATOM 675  O O   . CYS A 1 90  ? 93.410  74.359  142.202 1.00 146.10 ? 530 CYS C O   1 
ATOM 676  C CB  . CYS A 1 90  ? 91.388  71.813  141.864 1.00 150.18 ? 530 CYS C CB  1 
ATOM 677  S SG  . CYS A 1 90  ? 90.983  71.672  140.109 1.00 154.08 ? 530 CYS C SG  1 
ATOM 678  N N   . GLY A 1 91  ? 93.702  73.269  140.254 1.00 135.81 ? 531 GLY C N   1 
ATOM 679  C CA  . GLY A 1 91  ? 94.221  74.435  139.571 1.00 136.32 ? 531 GLY C CA  1 
ATOM 680  C C   . GLY A 1 91  ? 93.881  74.469  138.097 1.00 135.70 ? 531 GLY C C   1 
ATOM 681  O O   . GLY A 1 91  ? 93.058  73.681  137.622 1.00 133.13 ? 531 GLY C O   1 
ATOM 682  N N   . LEU A 1 92  ? 94.516  75.379  137.362 1.00 133.71 ? 532 LEU C N   1 
ATOM 683  C CA  . LEU A 1 92  ? 94.238  75.564  135.944 1.00 134.04 ? 532 LEU C CA  1 
ATOM 684  C C   . LEU A 1 92  ? 95.457  75.399  135.045 1.00 136.29 ? 532 LEU C C   1 
ATOM 685  O O   . LEU A 1 92  ? 95.346  75.602  133.829 1.00 135.80 ? 532 LEU C O   1 
ATOM 686  C CB  . LEU A 1 92  ? 93.633  76.949  135.705 1.00 134.11 ? 532 LEU C CB  1 
ATOM 687  C CG  . LEU A 1 92  ? 92.232  76.993  135.094 1.00 137.34 ? 532 LEU C CG  1 
ATOM 688  C CD1 . LEU A 1 92  ? 91.849  78.422  134.744 1.00 138.31 ? 532 LEU C CD1 1 
ATOM 689  C CD2 . LEU A 1 92  ? 92.134  76.087  133.879 1.00 137.02 ? 532 LEU C CD2 1 
ATOM 690  N N   . ASN A 1 93  ? 96.609  75.044  135.602 1.00 132.06 ? 533 ASN C N   1 
ATOM 691  C CA  . ASN A 1 93  ? 97.837  74.897  134.835 1.00 130.07 ? 533 ASN C CA  1 
ATOM 692  C C   . ASN A 1 93  ? 98.088  73.427  134.517 1.00 126.21 ? 533 ASN C C   1 
ATOM 693  O O   . ASN A 1 93  ? 97.469  72.526  135.087 1.00 125.77 ? 533 ASN C O   1 
ATOM 694  C CB  . ASN A 1 93  ? 99.030  75.506  135.578 1.00 123.17 ? 533 ASN C CB  1 
ATOM 695  C CG  . ASN A 1 93  ? 99.325  74.805  136.885 1.00 127.57 ? 533 ASN C CG  1 
ATOM 696  O OD1 . ASN A 1 93  ? 99.145  73.595  137.008 1.00 134.76 ? 533 ASN C OD1 1 
ATOM 697  N ND2 . ASN A 1 93  ? 99.780  75.565  137.873 1.00 125.40 ? 533 ASN C ND2 1 
ATOM 698  N N   . TRP A 1 94  ? 99.007  73.201  133.578 1.00 104.39 ? 534 TRP C N   1 
ATOM 699  C CA  . TRP A 1 94  ? 99.295  71.856  133.095 1.00 105.68 ? 534 TRP C CA  1 
ATOM 700  C C   . TRP A 1 94  ? 100.096 70.991  134.059 1.00 111.32 ? 534 TRP C C   1 
ATOM 701  O O   . TRP A 1 94  ? 99.970  69.762  134.028 1.00 112.95 ? 534 TRP C O   1 
ATOM 702  C CB  . TRP A 1 94  ? 100.051 71.980  131.773 1.00 105.94 ? 534 TRP C CB  1 
ATOM 703  C CG  . TRP A 1 94  ? 101.163 72.974  131.844 1.00 107.87 ? 534 TRP C CG  1 
ATOM 704  C CD1 . TRP A 1 94  ? 101.082 74.312  131.598 1.00 108.86 ? 534 TRP C CD1 1 
ATOM 705  C CD2 . TRP A 1 94  ? 102.524 72.715  132.204 1.00 107.63 ? 534 TRP C CD2 1 
ATOM 706  N NE1 . TRP A 1 94  ? 102.309 74.902  131.775 1.00 114.61 ? 534 TRP C NE1 1 
ATOM 707  C CE2 . TRP A 1 94  ? 103.212 73.942  132.148 1.00 110.83 ? 534 TRP C CE2 1 
ATOM 708  C CE3 . TRP A 1 94  ? 103.229 71.563  132.563 1.00 101.27 ? 534 TRP C CE3 1 
ATOM 709  C CZ2 . TRP A 1 94  ? 104.568 74.050  132.438 1.00 103.58 ? 534 TRP C CZ2 1 
ATOM 710  C CZ3 . TRP A 1 94  ? 104.574 71.673  132.851 1.00 104.82 ? 534 TRP C CZ3 1 
ATOM 711  C CH2 . TRP A 1 94  ? 105.230 72.906  132.788 1.00 105.06 ? 534 TRP C CH2 1 
ATOM 712  N N   . ALA A 1 95  ? 100.918 71.604  134.912 1.00 118.12 ? 535 ALA C N   1 
ATOM 713  C CA  . ALA A 1 95  ? 101.890 70.840  135.689 1.00 116.98 ? 535 ALA C CA  1 
ATOM 714  C C   . ALA A 1 95  ? 101.232 69.906  136.693 1.00 116.41 ? 535 ALA C C   1 
ATOM 715  O O   . ALA A 1 95  ? 101.801 68.862  137.028 1.00 118.50 ? 535 ALA C O   1 
ATOM 716  C CB  . ALA A 1 95  ? 102.846 71.790  136.409 1.00 113.05 ? 535 ALA C CB  1 
ATOM 717  N N   . ILE A 1 96  ? 100.047 70.258  137.189 1.00 121.63 ? 536 ILE C N   1 
ATOM 718  C CA  . ILE A 1 96  ? 99.475  69.519  138.309 1.00 118.43 ? 536 ILE C CA  1 
ATOM 719  C C   . ILE A 1 96  ? 99.026  68.128  137.870 1.00 120.35 ? 536 ILE C C   1 
ATOM 720  O O   . ILE A 1 96  ? 99.240  67.140  138.583 1.00 120.90 ? 536 ILE C O   1 
ATOM 721  C CB  . ILE A 1 96  ? 98.322  70.323  138.937 1.00 120.80 ? 536 ILE C CB  1 
ATOM 722  C CG1 . ILE A 1 96  ? 97.546  69.465  139.934 1.00 124.98 ? 536 ILE C CG1 1 
ATOM 723  C CG2 . ILE A 1 96  ? 97.391  70.858  137.865 1.00 121.13 ? 536 ILE C CG2 1 
ATOM 724  C CD1 . ILE A 1 96  ? 98.409  68.935  141.053 1.00 123.03 ? 536 ILE C CD1 1 
ATOM 725  N N   . PHE A 1 97  ? 98.415  68.022  136.693 1.00 132.53 ? 537 PHE C N   1 
ATOM 726  C CA  . PHE A 1 97  ? 97.741  66.788  136.311 1.00 136.09 ? 537 PHE C CA  1 
ATOM 727  C C   . PHE A 1 97  ? 98.747  65.686  136.000 1.00 136.37 ? 537 PHE C C   1 
ATOM 728  O O   . PHE A 1 97  ? 99.699  65.892  135.243 1.00 137.57 ? 537 PHE C O   1 
ATOM 729  C CB  . PHE A 1 97  ? 96.832  67.039  135.111 1.00 136.34 ? 537 PHE C CB  1 
ATOM 730  C CG  . PHE A 1 97  ? 95.572  67.772  135.460 1.00 135.90 ? 537 PHE C CG  1 
ATOM 731  C CD1 . PHE A 1 97  ? 94.464  67.088  135.925 1.00 135.99 ? 537 PHE C CD1 1 
ATOM 732  C CD2 . PHE A 1 97  ? 95.499  69.148  135.335 1.00 134.93 ? 537 PHE C CD2 1 
ATOM 733  C CE1 . PHE A 1 97  ? 93.306  67.761  136.253 1.00 138.42 ? 537 PHE C CE1 1 
ATOM 734  C CE2 . PHE A 1 97  ? 94.343  69.826  135.661 1.00 138.71 ? 537 PHE C CE2 1 
ATOM 735  C CZ  . PHE A 1 97  ? 93.245  69.132  136.120 1.00 139.93 ? 537 PHE C CZ  1 
ATOM 736  N N   . SER A 1 98  ? 98.526  64.510  136.591 1.00 136.65 ? 538 SER C N   1 
ATOM 737  C CA  . SER A 1 98  ? 99.455  63.395  136.440 1.00 136.17 ? 538 SER C CA  1 
ATOM 738  C C   . SER A 1 98  ? 99.283  62.672  135.109 1.00 134.82 ? 538 SER C C   1 
ATOM 739  O O   . SER A 1 98  ? 100.267 62.215  134.520 1.00 136.39 ? 538 SER C O   1 
ATOM 740  C CB  . SER A 1 98  ? 99.282  62.412  137.597 1.00 135.21 ? 538 SER C CB  1 
ATOM 741  O OG  . SER A 1 98  ? 99.531  61.084  137.174 1.00 136.82 ? 538 SER C OG  1 
ATOM 742  N N   . TYR A 1 99  ? 98.051  62.544  134.626 1.00 137.32 ? 539 TYR C N   1 
ATOM 743  C CA  . TYR A 1 99  ? 97.759  61.781  133.422 1.00 136.34 ? 539 TYR C CA  1 
ATOM 744  C C   . TYR A 1 99  ? 97.222  62.704  132.338 1.00 137.51 ? 539 TYR C C   1 
ATOM 745  O O   . TYR A 1 99  ? 96.531  63.684  132.631 1.00 143.30 ? 539 TYR C O   1 
ATOM 746  C CB  . TYR A 1 99  ? 96.748  60.665  133.708 1.00 136.93 ? 539 TYR C CB  1 
ATOM 747  C CG  . TYR A 1 99  ? 96.178  60.020  132.466 1.00 142.04 ? 539 TYR C CG  1 
ATOM 748  C CD1 . TYR A 1 99  ? 96.957  59.187  131.674 1.00 143.18 ? 539 TYR C CD1 1 
ATOM 749  C CD2 . TYR A 1 99  ? 94.865  60.250  132.080 1.00 144.27 ? 539 TYR C CD2 1 
ATOM 750  C CE1 . TYR A 1 99  ? 96.441  58.596  130.535 1.00 144.48 ? 539 TYR C CE1 1 
ATOM 751  C CE2 . TYR A 1 99  ? 94.340  59.665  130.943 1.00 145.30 ? 539 TYR C CE2 1 
ATOM 752  C CZ  . TYR A 1 99  ? 95.132  58.839  130.175 1.00 144.96 ? 539 TYR C CZ  1 
ATOM 753  O OH  . TYR A 1 99  ? 94.613  58.254  129.043 1.00 139.23 ? 539 TYR C OH  1 
ATOM 754  N N   . TRP A 1 100 ? 97.545  62.388  131.086 1.00 117.75 ? 540 TRP C N   1 
ATOM 755  C CA  . TRP A 1 100 ? 97.094  63.165  129.943 1.00 117.85 ? 540 TRP C CA  1 
ATOM 756  C C   . TRP A 1 100 ? 96.577  62.230  128.860 1.00 120.93 ? 540 TRP C C   1 
ATOM 757  O O   . TRP A 1 100 ? 97.049  61.100  128.714 1.00 121.20 ? 540 TRP C O   1 
ATOM 758  C CB  . TRP A 1 100 ? 98.219  64.037  129.379 1.00 117.15 ? 540 TRP C CB  1 
ATOM 759  C CG  . TRP A 1 100 ? 98.619  65.151  130.285 1.00 116.75 ? 540 TRP C CG  1 
ATOM 760  C CD1 . TRP A 1 100 ? 99.356  65.053  131.428 1.00 118.86 ? 540 TRP C CD1 1 
ATOM 761  C CD2 . TRP A 1 100 ? 98.303  66.537  130.129 1.00 116.70 ? 540 TRP C CD2 1 
ATOM 762  N NE1 . TRP A 1 100 ? 99.520  66.293  131.992 1.00 118.46 ? 540 TRP C NE1 1 
ATOM 763  C CE2 . TRP A 1 100 ? 98.882  67.221  131.213 1.00 119.46 ? 540 TRP C CE2 1 
ATOM 764  C CE3 . TRP A 1 100 ? 97.586  67.265  129.176 1.00 118.25 ? 540 TRP C CE3 1 
ATOM 765  C CZ2 . TRP A 1 100 ? 98.767  68.598  131.372 1.00 120.88 ? 540 TRP C CZ2 1 
ATOM 766  C CZ3 . TRP A 1 100 ? 97.473  68.631  129.335 1.00 117.29 ? 540 TRP C CZ3 1 
ATOM 767  C CH2 . TRP A 1 100 ? 98.061  69.284  130.424 1.00 119.36 ? 540 TRP C CH2 1 
ATOM 768  N N   . GLY A 1 101 ? 95.596  62.717  128.099 1.00 138.28 ? 541 GLY C N   1 
ATOM 769  C CA  . GLY A 1 101 ? 95.021  61.965  127.007 1.00 136.41 ? 541 GLY C CA  1 
ATOM 770  C C   . GLY A 1 101 ? 95.664  62.461  125.719 1.00 139.59 ? 541 GLY C C   1 
ATOM 771  O O   . GLY A 1 101 ? 96.416  63.431  125.688 1.00 141.56 ? 541 GLY C O   1 
ATOM 772  N N   . GLN A 1 102 ? 95.312  61.801  124.609 1.00 148.92 ? 542 GLN C N   1 
ATOM 773  C CA  . GLN A 1 102 ? 95.868  62.140  123.276 1.00 148.39 ? 542 GLN C CA  1 
ATOM 774  C C   . GLN A 1 102 ? 95.140  63.357  122.714 1.00 150.05 ? 542 GLN C C   1 
ATOM 775  O O   . GLN A 1 102 ? 95.659  63.969  121.775 1.00 148.79 ? 542 GLN C O   1 
ATOM 776  C CB  . GLN A 1 102 ? 95.743  60.916  122.373 1.00 146.26 ? 542 GLN C CB  1 
ATOM 777  C CG  . GLN A 1 102 ? 94.433  60.794  121.600 1.00 148.45 ? 542 GLN C CG  1 
ATOM 778  C CD  . GLN A 1 102 ? 93.212  60.726  122.488 1.00 150.99 ? 542 GLN C CD  1 
ATOM 779  O OE1 . GLN A 1 102 ? 93.190  60.019  123.501 1.00 151.16 ? 542 GLN C OE1 1 
ATOM 780  N NE2 . GLN A 1 102 ? 92.191  61.486  122.127 1.00 151.84 ? 542 GLN C NE2 1 
ATOM 781  N N   . GLY A 1 103 ? 93.950  63.651  123.206 1.00 157.29 ? 543 GLY C N   1 
ATOM 782  C CA  . GLY A 1 103 ? 93.221  64.834  122.804 1.00 156.76 ? 543 GLY C CA  1 
ATOM 783  C C   . GLY A 1 103 ? 92.555  64.784  121.441 1.00 158.14 ? 543 GLY C C   1 
ATOM 784  O O   . GLY A 1 103 ? 92.799  63.904  120.614 1.00 158.71 ? 543 GLY C O   1 
ATOM 785  N N   . THR A 1 104 ? 91.686  65.768  121.208 1.00 155.55 ? 544 THR C N   1 
ATOM 786  C CA  . THR A 1 104 ? 90.945  65.886  119.961 1.00 155.38 ? 544 THR C CA  1 
ATOM 787  C C   . THR A 1 104 ? 91.026  67.316  119.450 1.00 152.94 ? 544 THR C C   1 
ATOM 788  O O   . THR A 1 104 ? 91.009  68.268  120.236 1.00 152.00 ? 544 THR C O   1 
ATOM 789  C CB  . THR A 1 104 ? 89.478  65.482  120.141 1.00 155.45 ? 544 THR C CB  1 
ATOM 790  O OG1 . THR A 1 104 ? 89.394  64.368  121.039 1.00 154.48 ? 544 THR C OG1 1 
ATOM 791  C CG2 . THR A 1 104 ? 88.864  65.097  118.804 1.00 153.55 ? 544 THR C CG2 1 
ATOM 792  N N   . GLN A 1 105 ? 91.118  67.461  118.132 1.00 155.64 ? 545 GLN C N   1 
ATOM 793  C CA  . GLN A 1 105 ? 91.221  68.758  117.479 1.00 157.43 ? 545 GLN C CA  1 
ATOM 794  C C   . GLN A 1 105 ? 89.903  69.075  116.786 1.00 158.88 ? 545 GLN C C   1 
ATOM 795  O O   . GLN A 1 105 ? 89.407  68.270  115.991 1.00 157.97 ? 545 GLN C O   1 
ATOM 796  C CB  . GLN A 1 105 ? 92.369  68.768  116.468 1.00 158.66 ? 545 GLN C CB  1 
ATOM 797  C CG  . GLN A 1 105 ? 92.249  69.832  115.390 1.00 157.16 ? 545 GLN C CG  1 
ATOM 798  C CD  . GLN A 1 105 ? 92.343  71.236  115.947 1.00 158.61 ? 545 GLN C CD  1 
ATOM 799  O OE1 . GLN A 1 105 ? 91.397  72.017  115.857 1.00 161.11 ? 545 GLN C OE1 1 
ATOM 800  N NE2 . GLN A 1 105 ? 93.491  71.566  116.527 1.00 156.31 ? 545 GLN C NE2 1 
ATOM 801  N N   . VAL A 1 106 ? 89.342  70.244  117.086 1.00 159.64 ? 546 VAL C N   1 
ATOM 802  C CA  . VAL A 1 106 ? 88.068  70.672  116.523 1.00 159.19 ? 546 VAL C CA  1 
ATOM 803  C C   . VAL A 1 106 ? 88.241  72.059  115.921 1.00 159.99 ? 546 VAL C C   1 
ATOM 804  O O   . VAL A 1 106 ? 88.817  72.950  116.555 1.00 155.49 ? 546 VAL C O   1 
ATOM 805  C CB  . VAL A 1 106 ? 86.943  70.672  117.576 1.00 158.81 ? 546 VAL C CB  1 
ATOM 806  C CG1 . VAL A 1 106 ? 86.433  69.257  117.802 1.00 157.10 ? 546 VAL C CG1 1 
ATOM 807  C CG2 . VAL A 1 106 ? 87.432  71.273  118.880 1.00 157.84 ? 546 VAL C CG2 1 
ATOM 808  N N   . THR A 1 107 ? 87.746  72.235  114.700 1.00 178.39 ? 547 THR C N   1 
ATOM 809  C CA  . THR A 1 107 ? 87.829  73.499  113.984 1.00 179.08 ? 547 THR C CA  1 
ATOM 810  C C   . THR A 1 107 ? 86.491  74.224  114.071 1.00 179.84 ? 547 THR C C   1 
ATOM 811  O O   . THR A 1 107 ? 85.430  73.601  113.972 1.00 177.66 ? 547 THR C O   1 
ATOM 812  C CB  . THR A 1 107 ? 88.214  73.265  112.519 1.00 179.04 ? 547 THR C CB  1 
ATOM 813  O OG1 . THR A 1 107 ? 89.558  72.773  112.453 1.00 178.90 ? 547 THR C OG1 1 
ATOM 814  C CG2 . THR A 1 107 ? 88.120  74.554  111.715 1.00 178.67 ? 547 THR C CG2 1 
ATOM 815  N N   . VAL A 1 108 ? 86.567  75.543  114.301 1.00 186.99 ? 548 VAL C N   1 
ATOM 816  C CA  . VAL A 1 108 ? 85.350  76.394  114.444 1.00 187.14 ? 548 VAL C CA  1 
ATOM 817  C C   . VAL A 1 108 ? 84.484  76.267  113.187 1.00 188.60 ? 548 VAL C C   1 
ATOM 818  O O   . VAL A 1 108 ? 85.041  76.399  112.076 1.00 187.84 ? 548 VAL C O   1 
ATOM 819  C CB  . VAL A 1 108 ? 85.663  77.879  114.716 1.00 184.22 ? 548 VAL C CB  1 
ATOM 820  C CG1 . VAL A 1 108 ? 86.673  78.462  113.734 1.00 183.15 ? 548 VAL C CG1 1 
ATOM 821  C CG2 . VAL A 1 108 ? 84.389  78.717  114.726 1.00 184.77 ? 548 VAL C CG2 1 
ATOM 822  N N   . SER A 1 109 ? 83.189  76.006  113.355 1.00 190.93 ? 549 SER C N   1 
ATOM 823  C CA  . SER A 1 109 ? 82.220  75.946  112.270 1.00 189.34 ? 549 SER C CA  1 
ATOM 824  C C   . SER A 1 109 ? 81.080  76.903  112.581 1.00 188.53 ? 549 SER C C   1 
ATOM 825  O O   . SER A 1 109 ? 80.455  76.802  113.642 1.00 187.98 ? 549 SER C O   1 
ATOM 826  C CB  . SER A 1 109 ? 81.684  74.523  112.082 1.00 187.26 ? 549 SER C CB  1 
ATOM 827  O OG  . SER A 1 109 ? 82.719  73.565  112.222 1.00 184.78 ? 549 SER C OG  1 
ATOM 828  N N   . SER A 1 110 ? 80.812  77.821  111.654 1.00 179.29 ? 550 SER C N   1 
ATOM 829  C CA  . SER A 1 110 ? 79.780  78.843  111.826 1.00 180.14 ? 550 SER C CA  1 
ATOM 830  C C   . SER A 1 110 ? 80.012  79.671  113.088 1.00 179.49 ? 550 SER C C   1 
ATOM 831  O O   . SER A 1 110 ? 79.449  79.392  114.147 1.00 179.52 ? 550 SER C O   1 
ATOM 832  C CB  . SER A 1 110 ? 78.387  78.206  111.864 1.00 179.05 ? 550 SER C CB  1 
ATOM 833  O OG  . SER A 1 110 ? 77.440  79.084  112.448 1.00 177.83 ? 550 SER C OG  1 
ATOM 834  O OXT . SER A 1 110 ? 80.768  80.642  113.076 1.00 175.96 ? 550 SER C OXT 1 
ATOM 835  N N   . PRO B 2 32  ? 123.521 65.918  112.966 1.00 196.13 ? 33  PRO A N   1 
ATOM 836  C CA  . PRO B 2 32  ? 124.529 66.964  113.036 1.00 194.55 ? 33  PRO A CA  1 
ATOM 837  C C   . PRO B 2 32  ? 125.146 67.011  114.419 1.00 193.62 ? 33  PRO A C   1 
ATOM 838  O O   . PRO B 2 32  ? 126.089 67.785  114.640 1.00 193.54 ? 33  PRO A O   1 
ATOM 839  C CB  . PRO B 2 32  ? 123.718 68.214  112.716 1.00 193.11 ? 33  PRO A CB  1 
ATOM 840  C CG  . PRO B 2 32  ? 122.418 67.963  113.426 1.00 192.91 ? 33  PRO A CG  1 
ATOM 841  C CD  . PRO B 2 32  ? 122.199 66.469  113.253 1.00 193.72 ? 33  PRO A CD  1 
ATOM 842  N N   . CYS B 2 33  ? 124.637 66.203  115.344 1.00 190.80 ? 34  CYS A N   1 
ATOM 843  C CA  . CYS B 2 33  ? 125.156 66.182  116.704 1.00 190.70 ? 34  CYS A CA  1 
ATOM 844  C C   . CYS B 2 33  ? 126.646 65.869  116.696 1.00 191.94 ? 34  CYS A C   1 
ATOM 845  O O   . CYS B 2 33  ? 127.083 64.888  116.086 1.00 193.16 ? 34  CYS A O   1 
ATOM 846  C CB  . CYS B 2 33  ? 124.404 65.151  117.541 1.00 191.39 ? 34  CYS A CB  1 
ATOM 847  S SG  . CYS B 2 33  ? 122.745 65.658  118.033 1.00 200.59 ? 34  CYS A SG  1 
ATOM 848  N N   . SER B 2 34  ? 127.426 66.702  117.378 1.00 181.36 ? 35  SER A N   1 
ATOM 849  C CA  . SER B 2 34  ? 128.866 66.511  117.477 1.00 180.23 ? 35  SER A CA  1 
ATOM 850  C C   . SER B 2 34  ? 129.161 65.583  118.648 1.00 180.25 ? 35  SER A C   1 
ATOM 851  O O   . SER B 2 34  ? 128.802 65.885  119.791 1.00 180.17 ? 35  SER A O   1 
ATOM 852  C CB  . SER B 2 34  ? 129.582 67.849  117.653 1.00 178.70 ? 35  SER A CB  1 
ATOM 853  O OG  . SER B 2 34  ? 129.696 68.188  119.023 1.00 178.65 ? 35  SER A OG  1 
ATOM 854  N N   . CYS B 2 35  ? 129.811 64.460  118.363 1.00 202.53 ? 36  CYS A N   1 
ATOM 855  C CA  . CYS B 2 35  ? 130.095 63.435  119.358 1.00 203.46 ? 36  CYS A CA  1 
ATOM 856  C C   . CYS B 2 35  ? 131.562 63.522  119.754 1.00 203.96 ? 36  CYS A C   1 
ATOM 857  O O   . CYS B 2 35  ? 132.445 63.451  118.893 1.00 204.42 ? 36  CYS A O   1 
ATOM 858  C CB  . CYS B 2 35  ? 129.766 62.047  118.812 1.00 205.70 ? 36  CYS A CB  1 
ATOM 859  S SG  . CYS B 2 35  ? 129.424 60.804  120.071 1.00 208.51 ? 36  CYS A SG  1 
ATOM 860  N N   . ASP B 2 36  ? 131.818 63.675  121.054 1.00 191.68 ? 37  ASP A N   1 
ATOM 861  C CA  . ASP B 2 36  ? 133.187 63.736  121.546 1.00 191.34 ? 37  ASP A CA  1 
ATOM 862  C C   . ASP B 2 36  ? 133.809 62.358  121.728 1.00 191.69 ? 37  ASP A C   1 
ATOM 863  O O   . ASP B 2 36  ? 135.031 62.261  121.879 1.00 190.48 ? 37  ASP A O   1 
ATOM 864  C CB  . ASP B 2 36  ? 133.237 64.504  122.868 1.00 189.67 ? 37  ASP A CB  1 
ATOM 865  C CG  . ASP B 2 36  ? 132.645 65.894  122.756 1.00 190.16 ? 37  ASP A CG  1 
ATOM 866  O OD1 . ASP B 2 36  ? 131.739 66.090  121.919 1.00 190.95 ? 37  ASP A OD1 1 
ATOM 867  O OD2 . ASP B 2 36  ? 133.085 66.791  123.505 1.00 190.41 ? 37  ASP A OD2 1 
ATOM 868  N N   . GLY B 2 37  ? 133.003 61.298  121.718 1.00 193.95 ? 38  GLY A N   1 
ATOM 869  C CA  . GLY B 2 37  ? 133.508 59.949  121.852 1.00 192.86 ? 38  GLY A CA  1 
ATOM 870  C C   . GLY B 2 37  ? 133.816 59.507  123.265 1.00 193.46 ? 38  GLY A C   1 
ATOM 871  O O   . GLY B 2 37  ? 134.276 58.373  123.453 1.00 192.67 ? 38  GLY A O   1 
ATOM 872  N N   . ASP B 2 38  ? 133.581 60.355  124.263 1.00 186.35 ? 39  ASP A N   1 
ATOM 873  C CA  . ASP B 2 38  ? 133.834 60.032  125.663 1.00 185.13 ? 39  ASP A CA  1 
ATOM 874  C C   . ASP B 2 38  ? 132.529 59.897  126.441 1.00 184.09 ? 39  ASP A C   1 
ATOM 875  O O   . ASP B 2 38  ? 132.415 60.359  127.578 1.00 182.60 ? 39  ASP A O   1 
ATOM 876  C CB  . ASP B 2 38  ? 134.731 61.085  126.307 1.00 183.22 ? 39  ASP A CB  1 
ATOM 877  C CG  . ASP B 2 38  ? 134.330 62.497  125.934 1.00 183.36 ? 39  ASP A CG  1 
ATOM 878  O OD1 . ASP B 2 38  ? 133.196 62.683  125.445 1.00 183.51 ? 39  ASP A OD1 1 
ATOM 879  O OD2 . ASP B 2 38  ? 135.145 63.422  126.130 1.00 183.43 ? 39  ASP A OD2 1 
ATOM 880  N N   . ARG B 2 39  ? 131.527 59.274  125.819 1.00 161.83 ? 40  ARG A N   1 
ATOM 881  C CA  . ARG B 2 39  ? 130.185 59.123  126.378 1.00 157.99 ? 40  ARG A CA  1 
ATOM 882  C C   . ARG B 2 39  ? 129.516 60.470  126.634 1.00 156.70 ? 40  ARG A C   1 
ATOM 883  O O   . ARG B 2 39  ? 128.616 60.571  127.474 1.00 158.62 ? 40  ARG A O   1 
ATOM 884  C CB  . ARG B 2 39  ? 130.201 58.287  127.665 1.00 157.35 ? 40  ARG A CB  1 
ATOM 885  C CG  . ARG B 2 39  ? 130.973 56.980  127.553 1.00 156.73 ? 40  ARG A CG  1 
ATOM 886  C CD  . ARG B 2 39  ? 130.044 55.794  127.348 1.00 158.45 ? 40  ARG A CD  1 
ATOM 887  N NE  . ARG B 2 39  ? 129.242 55.924  126.137 1.00 162.18 ? 40  ARG A NE  1 
ATOM 888  C CZ  . ARG B 2 39  ? 129.695 55.704  124.910 1.00 161.05 ? 40  ARG A CZ  1 
ATOM 889  N NH1 . ARG B 2 39  ? 130.945 55.333  124.690 1.00 158.93 ? 40  ARG A NH1 1 
ATOM 890  N NH2 . ARG B 2 39  ? 128.871 55.860  123.877 1.00 160.79 ? 40  ARG A NH2 1 
ATOM 891  N N   . ARG B 2 40  ? 129.944 61.510  125.922 1.00 149.05 ? 41  ARG A N   1 
ATOM 892  C CA  . ARG B 2 40  ? 129.372 62.844  126.037 1.00 150.10 ? 41  ARG A CA  1 
ATOM 893  C C   . ARG B 2 40  ? 128.979 63.319  124.647 1.00 151.53 ? 41  ARG A C   1 
ATOM 894  O O   . ARG B 2 40  ? 129.773 63.215  123.707 1.00 153.44 ? 41  ARG A O   1 
ATOM 895  C CB  . ARG B 2 40  ? 130.366 63.816  126.681 1.00 149.90 ? 41  ARG A CB  1 
ATOM 896  C CG  . ARG B 2 40  ? 130.110 65.280  126.371 1.00 149.67 ? 41  ARG A CG  1 
ATOM 897  C CD  . ARG B 2 40  ? 131.006 66.174  127.211 1.00 150.55 ? 41  ARG A CD  1 
ATOM 898  N NE  . ARG B 2 40  ? 131.238 65.619  128.539 1.00 152.18 ? 41  ARG A NE  1 
ATOM 899  C CZ  . ARG B 2 40  ? 130.551 65.954  129.622 1.00 150.65 ? 41  ARG A CZ  1 
ATOM 900  N NH1 . ARG B 2 40  ? 129.586 66.858  129.577 1.00 151.02 ? 41  ARG A NH1 1 
ATOM 901  N NH2 . ARG B 2 40  ? 130.841 65.370  130.781 1.00 147.21 ? 41  ARG A NH2 1 
ATOM 902  N N   . VAL B 2 41  ? 127.728 63.773  124.520 1.00 138.57 ? 42  VAL A N   1 
ATOM 903  C CA  . VAL B 2 41  ? 127.139 64.169  123.214 1.00 135.95 ? 42  VAL A CA  1 
ATOM 904  C C   . VAL B 2 41  ? 126.771 65.651  123.251 1.00 134.76 ? 42  VAL A C   1 
ATOM 905  O O   . VAL B 2 41  ? 126.195 66.073  124.276 1.00 138.09 ? 42  VAL A O   1 
ATOM 906  C CB  . VAL B 2 41  ? 125.887 63.308  122.971 1.00 136.73 ? 42  VAL A CB  1 
ATOM 907  C CG1 . VAL B 2 41  ? 124.945 63.929  121.947 1.00 135.89 ? 42  VAL A CG1 1 
ATOM 908  C CG2 . VAL B 2 41  ? 126.246 61.881  122.585 1.00 141.02 ? 42  VAL A CG2 1 
ATOM 909  N N   . ASP B 2 42  ? 127.098 66.400  122.204 1.00 140.99 ? 43  ASP A N   1 
ATOM 910  C CA  . ASP B 2 42  ? 126.711 67.795  122.053 1.00 143.10 ? 43  ASP A CA  1 
ATOM 911  C C   . ASP B 2 42  ? 125.779 67.923  120.856 1.00 144.08 ? 43  ASP A C   1 
ATOM 912  O O   . ASP B 2 42  ? 126.072 67.398  119.777 1.00 148.09 ? 43  ASP A O   1 
ATOM 913  C CB  . ASP B 2 42  ? 127.941 68.689  121.872 1.00 143.04 ? 43  ASP A CB  1 
ATOM 914  C CG  . ASP B 2 42  ? 127.637 70.159  122.095 1.00 143.97 ? 43  ASP A CG  1 
ATOM 915  O OD1 . ASP B 2 42  ? 126.484 70.580  121.865 1.00 145.68 ? 43  ASP A OD1 1 
ATOM 916  O OD2 . ASP B 2 42  ? 128.557 70.898  122.503 1.00 145.61 ? 43  ASP A OD2 1 
ATOM 917  N N   . CYS B 2 43  ? 124.656 68.622  121.052 1.00 132.46 ? 44  CYS A N   1 
ATOM 918  C CA  . CYS B 2 43  ? 123.708 68.861  119.970 1.00 129.68 ? 44  CYS A CA  1 
ATOM 919  C C   . CYS B 2 43  ? 123.192 70.295  119.974 1.00 130.37 ? 44  CYS A C   1 
ATOM 920  O O   . CYS B 2 43  ? 122.160 70.574  119.352 1.00 133.04 ? 44  CYS A O   1 
ATOM 921  C CB  . CYS B 2 43  ? 122.520 67.898  120.054 1.00 132.86 ? 44  CYS A CB  1 
ATOM 922  S SG  . CYS B 2 43  ? 122.954 66.150  119.991 1.00 154.28 ? 44  CYS A SG  1 
ATOM 923  N N   . SER B 2 44  ? 123.875 71.206  120.660 1.00 119.54 ? 45  SER A N   1 
ATOM 924  C CA  . SER B 2 44  ? 123.381 72.567  120.805 1.00 121.46 ? 45  SER A CA  1 
ATOM 925  C C   . SER B 2 44  ? 123.385 73.302  119.471 1.00 119.63 ? 45  SER A C   1 
ATOM 926  O O   . SER B 2 44  ? 124.309 73.163  118.666 1.00 121.69 ? 45  SER A O   1 
ATOM 927  C CB  . SER B 2 44  ? 124.229 73.329  121.821 1.00 121.72 ? 45  SER A CB  1 
ATOM 928  O OG  . SER B 2 44  ? 124.320 74.701  121.479 1.00 121.11 ? 45  SER A OG  1 
ATOM 929  N N   . GLY B 2 45  ? 122.335 74.088  119.240 1.00 116.83 ? 46  GLY A N   1 
ATOM 930  C CA  . GLY B 2 45  ? 122.263 74.968  118.094 1.00 116.89 ? 46  GLY A CA  1 
ATOM 931  C C   . GLY B 2 45  ? 121.966 74.546  116.673 1.00 119.39 ? 46  GLY A C   1 
ATOM 932  O O   . GLY B 2 45  ? 121.900 75.413  115.793 1.00 122.39 ? 46  GLY A O   1 
ATOM 933  N N   . LYS B 2 46  ? 121.780 73.251  116.415 1.00 140.53 ? 47  LYS A N   1 
ATOM 934  C CA  . LYS B 2 46  ? 121.456 72.833  115.047 1.00 143.54 ? 47  LYS A CA  1 
ATOM 935  C C   . LYS B 2 46  ? 119.904 72.847  114.637 1.00 142.68 ? 47  LYS A C   1 
ATOM 936  O O   . LYS B 2 46  ? 119.422 72.454  113.570 1.00 142.68 ? 47  LYS A O   1 
ATOM 937  C CB  . LYS B 2 46  ? 121.761 71.346  114.884 1.00 144.50 ? 47  LYS A CB  1 
ATOM 938  C CG  . LYS B 2 46  ? 123.222 70.991  115.104 1.00 146.61 ? 47  LYS A CG  1 
ATOM 939  C CD  . LYS B 2 46  ? 124.115 71.640  114.060 1.00 144.18 ? 47  LYS A CD  1 
ATOM 940  C CE  . LYS B 2 46  ? 125.564 71.221  114.243 1.00 142.79 ? 47  LYS A CE  1 
ATOM 941  N NZ  . LYS B 2 46  ? 126.455 71.869  113.242 1.00 145.60 ? 47  LYS A NZ  1 
ATOM 942  N N   . GLY B 2 47  ? 119.170 73.437  115.576 1.00 124.83 ? 48  GLY A N   1 
ATOM 943  C CA  . GLY B 2 47  ? 117.763 73.710  115.387 1.00 121.24 ? 48  GLY A CA  1 
ATOM 944  C C   . GLY B 2 47  ? 116.697 72.638  115.359 1.00 124.20 ? 48  GLY A C   1 
ATOM 945  O O   . GLY B 2 47  ? 115.549 72.945  115.013 1.00 124.07 ? 48  GLY A O   1 
ATOM 946  N N   . LEU B 2 48  ? 117.027 71.398  115.708 1.00 124.60 ? 49  LEU A N   1 
ATOM 947  C CA  . LEU B 2 48  ? 116.028 70.338  115.700 1.00 125.11 ? 49  LEU A CA  1 
ATOM 948  C C   . LEU B 2 48  ? 115.042 70.528  116.848 1.00 124.68 ? 49  LEU A C   1 
ATOM 949  O O   . LEU B 2 48  ? 115.414 70.942  117.948 1.00 125.10 ? 49  LEU A O   1 
ATOM 950  C CB  . LEU B 2 48  ? 116.699 68.965  115.783 1.00 125.03 ? 49  LEU A CB  1 
ATOM 951  C CG  . LEU B 2 48  ? 117.285 68.458  117.102 1.00 122.87 ? 49  LEU A CG  1 
ATOM 952  C CD1 . LEU B 2 48  ? 117.338 66.940  117.094 1.00 122.73 ? 49  LEU A CD1 1 
ATOM 953  C CD2 . LEU B 2 48  ? 118.672 69.023  117.332 1.00 122.34 ? 49  LEU A CD2 1 
ATOM 954  N N   . THR B 2 49  ? 113.774 70.229  116.580 1.00 126.88 ? 50  THR A N   1 
ATOM 955  C CA  . THR B 2 49  ? 112.699 70.486  117.528 1.00 128.01 ? 50  THR A CA  1 
ATOM 956  C C   . THR B 2 49  ? 112.321 69.267  118.359 1.00 129.27 ? 50  THR A C   1 
ATOM 957  O O   . THR B 2 49  ? 111.404 69.360  119.181 1.00 131.25 ? 50  THR A O   1 
ATOM 958  C CB  . THR B 2 49  ? 111.459 70.999  116.791 1.00 129.66 ? 50  THR A CB  1 
ATOM 959  O OG1 . THR B 2 49  ? 110.656 69.887  116.376 1.00 131.83 ? 50  THR A OG1 1 
ATOM 960  C CG2 . THR B 2 49  ? 111.864 71.810  115.570 1.00 128.02 ? 50  THR A CG2 1 
ATOM 961  N N   . ALA B 2 50  ? 112.993 68.136  118.171 1.00 124.75 ? 51  ALA A N   1 
ATOM 962  C CA  . ALA B 2 50  ? 112.695 66.921  118.913 1.00 123.98 ? 51  ALA A CA  1 
ATOM 963  C C   . ALA B 2 50  ? 113.972 66.386  119.545 1.00 124.75 ? 51  ALA A C   1 
ATOM 964  O O   . ALA B 2 50  ? 115.067 66.912  119.333 1.00 127.52 ? 51  ALA A O   1 
ATOM 965  C CB  . ALA B 2 50  ? 112.057 65.856  118.012 1.00 122.96 ? 51  ALA A CB  1 
ATOM 966  N N   . VAL B 2 51  ? 113.819 65.335  120.339 1.00 139.33 ? 52  VAL A N   1 
ATOM 967  C CA  . VAL B 2 51  ? 114.985 64.685  120.950 1.00 142.18 ? 52  VAL A CA  1 
ATOM 968  C C   . VAL B 2 51  ? 115.779 63.965  119.867 1.00 146.82 ? 52  VAL A C   1 
ATOM 969  O O   . VAL B 2 51  ? 115.177 63.315  118.992 1.00 146.14 ? 52  VAL A O   1 
ATOM 970  C CB  . VAL B 2 51  ? 114.537 63.719  122.052 1.00 140.58 ? 52  VAL A CB  1 
ATOM 971  C CG1 . VAL B 2 51  ? 113.472 62.762  121.533 1.00 141.60 ? 52  VAL A CG1 1 
ATOM 972  C CG2 . VAL B 2 51  ? 115.723 62.947  122.608 1.00 138.02 ? 52  VAL A CG2 1 
ATOM 973  N N   . PRO B 2 52  ? 117.108 64.070  119.854 1.00 152.86 ? 53  PRO A N   1 
ATOM 974  C CA  . PRO B 2 52  ? 117.890 63.354  118.840 1.00 147.69 ? 53  PRO A CA  1 
ATOM 975  C C   . PRO B 2 52  ? 117.724 61.848  118.968 1.00 148.57 ? 53  PRO A C   1 
ATOM 976  O O   . PRO B 2 52  ? 117.547 61.309  120.062 1.00 149.19 ? 53  PRO A O   1 
ATOM 977  C CB  . PRO B 2 52  ? 119.333 63.786  119.130 1.00 146.17 ? 53  PRO A CB  1 
ATOM 978  C CG  . PRO B 2 52  ? 119.205 65.067  119.882 1.00 146.43 ? 53  PRO A CG  1 
ATOM 979  C CD  . PRO B 2 52  ? 117.950 64.945  120.687 1.00 149.48 ? 53  PRO A CD  1 
ATOM 980  N N   . GLU B 2 53  ? 117.786 61.171  117.827 1.00 166.32 ? 54  GLU A N   1 
ATOM 981  C CA  . GLU B 2 53  ? 117.604 59.731  117.752 1.00 167.30 ? 54  GLU A CA  1 
ATOM 982  C C   . GLU B 2 53  ? 118.834 59.086  117.128 1.00 167.62 ? 54  GLU A C   1 
ATOM 983  O O   . GLU B 2 53  ? 119.639 59.744  116.464 1.00 167.84 ? 54  GLU A O   1 
ATOM 984  C CB  . GLU B 2 53  ? 116.352 59.367  116.941 1.00 165.97 ? 54  GLU A CB  1 
ATOM 985  C CG  . GLU B 2 53  ? 116.401 59.807  115.485 1.00 165.75 ? 54  GLU A CG  1 
ATOM 986  C CD  . GLU B 2 53  ? 115.985 61.253  115.293 1.00 167.93 ? 54  GLU A CD  1 
ATOM 987  O OE1 . GLU B 2 53  ? 115.784 61.958  116.304 1.00 169.14 ? 54  GLU A OE1 1 
ATOM 988  O OE2 . GLU B 2 53  ? 115.859 61.686  114.128 1.00 168.36 ? 54  GLU A OE2 1 
ATOM 989  N N   . GLY B 2 54  ? 118.969 57.782  117.352 1.00 170.51 ? 55  GLY A N   1 
ATOM 990  C CA  . GLY B 2 54  ? 120.129 57.055  116.881 1.00 170.82 ? 55  GLY A CA  1 
ATOM 991  C C   . GLY B 2 54  ? 121.367 57.221  117.729 1.00 171.23 ? 55  GLY A C   1 
ATOM 992  O O   . GLY B 2 54  ? 122.443 56.768  117.323 1.00 170.92 ? 55  GLY A O   1 
ATOM 993  N N   . LEU B 2 55  ? 121.213 57.861  118.898 1.00 161.40 ? 56  LEU A N   1 
ATOM 994  C CA  . LEU B 2 55  ? 122.344 58.141  119.817 1.00 159.56 ? 56  LEU A CA  1 
ATOM 995  C C   . LEU B 2 55  ? 122.775 56.851  120.517 1.00 158.53 ? 56  LEU A C   1 
ATOM 996  O O   . LEU B 2 55  ? 121.931 55.936  120.629 1.00 157.81 ? 56  LEU A O   1 
ATOM 997  C CB  . LEU B 2 55  ? 121.913 59.174  120.858 1.00 158.92 ? 56  LEU A CB  1 
ATOM 998  C CG  . LEU B 2 55  ? 122.570 60.559  120.836 1.00 159.03 ? 56  LEU A CG  1 
ATOM 999  C CD1 . LEU B 2 55  ? 122.519 61.087  122.258 1.00 156.24 ? 56  LEU A CD1 1 
ATOM 1000 C CD2 . LEU B 2 55  ? 123.992 60.618  120.316 1.00 158.80 ? 56  LEU A CD2 1 
ATOM 1001 N N   . SER B 2 56  ? 124.018 56.783  120.999 1.00 158.03 ? 57  SER A N   1 
ATOM 1002 C CA  . SER B 2 56  ? 124.512 55.631  121.737 1.00 158.09 ? 57  SER A CA  1 
ATOM 1003 C C   . SER B 2 56  ? 123.662 55.388  122.978 1.00 157.57 ? 57  SER A C   1 
ATOM 1004 O O   . SER B 2 56  ? 123.164 56.321  123.611 1.00 159.17 ? 57  SER A O   1 
ATOM 1005 C CB  . SER B 2 56  ? 125.972 55.838  122.137 1.00 158.18 ? 57  SER A CB  1 
ATOM 1006 O OG  . SER B 2 56  ? 126.070 56.310  123.470 1.00 157.46 ? 57  SER A OG  1 
ATOM 1007 N N   . ALA B 2 57  ? 123.492 54.113  123.319 1.00 157.45 ? 58  ALA A N   1 
ATOM 1008 C CA  . ALA B 2 57  ? 122.720 53.747  124.498 1.00 158.52 ? 58  ALA A CA  1 
ATOM 1009 C C   . ALA B 2 57  ? 123.494 53.932  125.795 1.00 158.51 ? 58  ALA A C   1 
ATOM 1010 O O   . ALA B 2 57  ? 122.893 53.844  126.871 1.00 158.00 ? 58  ALA A O   1 
ATOM 1011 C CB  . ALA B 2 57  ? 122.245 52.297  124.387 1.00 157.54 ? 58  ALA A CB  1 
ATOM 1012 N N   . PHE B 2 58  ? 124.799 54.182  125.724 1.00 159.76 ? 59  PHE A N   1 
ATOM 1013 C CA  . PHE B 2 58  ? 125.640 54.298  126.907 1.00 160.69 ? 59  PHE A CA  1 
ATOM 1014 C C   . PHE B 2 58  ? 126.033 55.736  127.220 1.00 158.90 ? 59  PHE A C   1 
ATOM 1015 O O   . PHE B 2 58  ? 126.850 55.959  128.118 1.00 161.27 ? 59  PHE A O   1 
ATOM 1016 C CB  . PHE B 2 58  ? 126.896 53.441  126.743 1.00 161.08 ? 59  PHE A CB  1 
ATOM 1017 C CG  . PHE B 2 58  ? 126.613 51.975  126.601 1.00 160.44 ? 59  PHE A CG  1 
ATOM 1018 C CD1 . PHE B 2 58  ? 125.942 51.286  127.597 1.00 159.47 ? 59  PHE A CD1 1 
ATOM 1019 C CD2 . PHE B 2 58  ? 127.016 51.284  125.471 1.00 160.55 ? 59  PHE A CD2 1 
ATOM 1020 C CE1 . PHE B 2 58  ? 125.679 49.936  127.469 1.00 160.63 ? 59  PHE A CE1 1 
ATOM 1021 C CE2 . PHE B 2 58  ? 126.756 49.934  125.337 1.00 161.57 ? 59  PHE A CE2 1 
ATOM 1022 C CZ  . PHE B 2 58  ? 126.086 49.259  126.337 1.00 161.84 ? 59  PHE A CZ  1 
ATOM 1023 N N   . THR B 2 59  ? 125.479 56.712  126.506 1.00 139.30 ? 60  THR A N   1 
ATOM 1024 C CA  . THR B 2 59  ? 125.837 58.101  126.754 1.00 140.56 ? 60  THR A CA  1 
ATOM 1025 C C   . THR B 2 59  ? 125.469 58.565  128.159 1.00 141.20 ? 60  THR A C   1 
ATOM 1026 O O   . THR B 2 59  ? 124.446 58.167  128.723 1.00 141.02 ? 60  THR A O   1 
ATOM 1027 C CB  . THR B 2 59  ? 125.251 59.013  125.678 1.00 139.86 ? 60  THR A CB  1 
ATOM 1028 O OG1 . THR B 2 59  ? 125.465 60.381  126.043 1.00 140.04 ? 60  THR A OG1 1 
ATOM 1029 C CG2 . THR B 2 59  ? 123.762 58.770  125.531 1.00 141.78 ? 60  THR A CG2 1 
ATOM 1030 N N   . GLN B 2 60  ? 126.315 59.446  128.704 1.00 133.12 ? 61  GLN A N   1 
ATOM 1031 C CA  . GLN B 2 60  ? 126.160 59.987  130.061 1.00 128.74 ? 61  GLN A CA  1 
ATOM 1032 C C   . GLN B 2 60  ? 126.069 61.537  130.189 1.00 128.60 ? 61  GLN A C   1 
ATOM 1033 O O   . GLN B 2 60  ? 125.975 62.045  131.294 1.00 133.63 ? 61  GLN A O   1 
ATOM 1034 C CB  . GLN B 2 60  ? 127.295 59.301  130.802 1.00 131.85 ? 61  GLN A CB  1 
ATOM 1035 C CG  . GLN B 2 60  ? 127.139 57.790  130.909 1.00 137.15 ? 61  GLN A CG  1 
ATOM 1036 C CD  . GLN B 2 60  ? 128.316 57.130  131.586 1.00 136.56 ? 61  GLN A CD  1 
ATOM 1037 O OE1 . GLN B 2 60  ? 129.435 57.652  131.588 1.00 135.24 ? 61  GLN A OE1 1 
ATOM 1038 N NE2 . GLN B 2 60  ? 128.067 55.963  132.160 1.00 134.47 ? 61  GLN A NE2 1 
ATOM 1039 N N   . ALA B 2 61  ? 126.331 62.245  129.108 1.00 122.78 ? 62  ALA A N   1 
ATOM 1040 C CA  . ALA B 2 61  ? 126.053 63.667  128.974 1.00 126.25 ? 62  ALA A CA  1 
ATOM 1041 C C   . ALA B 2 61  ? 125.438 64.026  127.632 1.00 129.36 ? 62  ALA A C   1 
ATOM 1042 O O   . ALA B 2 61  ? 125.918 63.575  126.588 1.00 132.09 ? 62  ALA A O   1 
ATOM 1043 C CB  . ALA B 2 61  ? 127.419 64.338  129.135 1.00 129.48 ? 62  ALA A CB  1 
ATOM 1044 N N   . LEU B 2 62  ? 124.381 64.833  127.660 1.00 119.68 ? 63  LEU A N   1 
ATOM 1045 C CA  . LEU B 2 62  ? 123.636 65.169  126.459 1.00 114.31 ? 63  LEU A CA  1 
ATOM 1046 C C   . LEU B 2 62  ? 123.171 66.614  126.561 1.00 110.27 ? 63  LEU A C   1 
ATOM 1047 O O   . LEU B 2 62  ? 122.727 67.057  127.624 1.00 114.18 ? 63  LEU A O   1 
ATOM 1048 C CB  . LEU B 2 62  ? 122.450 64.211  126.283 1.00 109.71 ? 63  LEU A CB  1 
ATOM 1049 C CG  . LEU B 2 62  ? 121.867 63.968  124.890 1.00 113.53 ? 63  LEU A CG  1 
ATOM 1050 C CD1 . LEU B 2 62  ? 121.023 62.705  124.898 1.00 115.07 ? 63  LEU A CD1 1 
ATOM 1051 C CD2 . LEU B 2 62  ? 121.052 65.134  124.409 1.00 113.19 ? 63  LEU A CD2 1 
ATOM 1052 N N   . ASP B 2 63  ? 123.276 67.348  125.455 1.00 105.42 ? 64  ASP A N   1 
ATOM 1053 C CA  . ASP B 2 63  ? 123.027 68.790  125.430 1.00 107.20 ? 64  ASP A CA  1 
ATOM 1054 C C   . ASP B 2 63  ? 122.100 69.112  124.261 1.00 111.59 ? 64  ASP A C   1 
ATOM 1055 O O   . ASP B 2 63  ? 122.436 68.842  123.105 1.00 116.58 ? 64  ASP A O   1 
ATOM 1056 C CB  . ASP B 2 63  ? 124.339 69.561  125.324 1.00 105.89 ? 64  ASP A CB  1 
ATOM 1057 C CG  . ASP B 2 63  ? 124.167 71.048  125.556 1.00 110.83 ? 64  ASP A CG  1 
ATOM 1058 O OD1 . ASP B 2 63  ? 123.014 71.509  125.683 1.00 119.15 ? 64  ASP A OD1 1 
ATOM 1059 O OD2 . ASP B 2 63  ? 125.191 71.760  125.610 1.00 113.00 ? 64  ASP A OD2 1 
ATOM 1060 N N   . ILE B 2 64  ? 120.936 69.690  124.562 1.00 95.87  ? 65  ILE A N   1 
ATOM 1061 C CA  . ILE B 2 64  ? 119.977 70.067  123.529 1.00 90.60  ? 65  ILE A CA  1 
ATOM 1062 C C   . ILE B 2 64  ? 119.669 71.556  123.630 1.00 92.81  ? 65  ILE A C   1 
ATOM 1063 O O   . ILE B 2 64  ? 118.591 72.005  123.226 1.00 102.27 ? 65  ILE A O   1 
ATOM 1064 C CB  . ILE B 2 64  ? 118.683 69.239  123.631 1.00 93.63  ? 65  ILE A CB  1 
ATOM 1065 C CG1 . ILE B 2 64  ? 118.974 67.852  124.190 1.00 94.83  ? 65  ILE A CG1 1 
ATOM 1066 C CG2 . ILE B 2 64  ? 118.042 69.089  122.266 1.00 105.11 ? 65  ILE A CG2 1 
ATOM 1067 C CD1 . ILE B 2 64  ? 117.762 66.952  124.265 1.00 96.07  ? 65  ILE A CD1 1 
ATOM 1068 N N   . SER B 2 65  ? 120.603 72.333  124.169 1.00 101.80 ? 66  SER A N   1 
ATOM 1069 C CA  . SER B 2 65  ? 120.370 73.761  124.308 1.00 104.86 ? 66  SER A CA  1 
ATOM 1070 C C   . SER B 2 65  ? 120.337 74.434  122.936 1.00 108.46 ? 66  SER A C   1 
ATOM 1071 O O   . SER B 2 65  ? 120.664 73.833  121.910 1.00 120.32 ? 66  SER A O   1 
ATOM 1072 C CB  . SER B 2 65  ? 121.443 74.398  125.189 1.00 106.08 ? 66  SER A CB  1 
ATOM 1073 O OG  . SER B 2 65  ? 122.728 73.904  124.862 1.00 113.03 ? 66  SER A OG  1 
ATOM 1074 N N   . MET B 2 66  ? 119.861 75.689  122.973 1.00 106.37 ? 67  MET A N   1 
ATOM 1075 C CA  . MET B 2 66  ? 119.777 76.582  121.798 1.00 110.51 ? 67  MET A CA  1 
ATOM 1076 C C   . MET B 2 66  ? 118.805 76.045  120.753 1.00 112.85 ? 67  MET A C   1 
ATOM 1077 O O   . MET B 2 66  ? 118.549 76.772  119.801 1.00 121.17 ? 67  MET A O   1 
ATOM 1078 C CB  . MET B 2 66  ? 121.145 76.774  121.158 1.00 119.26 ? 67  MET A CB  1 
ATOM 1079 C CG  . MET B 2 66  ? 122.292 76.851  122.130 1.00 119.98 ? 67  MET A CG  1 
ATOM 1080 S SD  . MET B 2 66  ? 121.978 78.030  123.450 1.00 132.84 ? 67  MET A SD  1 
ATOM 1081 C CE  . MET B 2 66  ? 121.829 79.508  122.440 1.00 119.09 ? 67  MET A CE  1 
ATOM 1082 N N   . ASN B 2 67  ? 118.234 74.877  120.938 1.00 103.96 ? 68  ASN A N   1 
ATOM 1083 C CA  . ASN B 2 67  ? 117.353 74.248  119.970 1.00 104.94 ? 68  ASN A CA  1 
ATOM 1084 C C   . ASN B 2 67  ? 115.987 74.930  119.986 1.00 109.87 ? 68  ASN A C   1 
ATOM 1085 O O   . ASN B 2 67  ? 115.794 75.977  120.608 1.00 112.09 ? 68  ASN A O   1 
ATOM 1086 C CB  . ASN B 2 67  ? 117.249 72.753  120.251 1.00 106.43 ? 68  ASN A CB  1 
ATOM 1087 C CG  . ASN B 2 67  ? 118.104 71.932  119.318 1.00 111.44 ? 68  ASN A CG  1 
ATOM 1088 O OD1 . ASN B 2 67  ? 117.948 71.998  118.101 1.00 114.30 ? 68  ASN A OD1 1 
ATOM 1089 N ND2 . ASN B 2 67  ? 119.019 71.156  119.881 1.00 113.77 ? 68  ASN A ND2 1 
ATOM 1090 N N   . ASN B 2 68  ? 115.020 74.331  119.298 1.00 110.88 ? 69  ASN A N   1 
ATOM 1091 C CA  . ASN B 2 68  ? 113.663 74.852  119.200 1.00 112.33 ? 69  ASN A CA  1 
ATOM 1092 C C   . ASN B 2 68  ? 112.645 73.805  119.632 1.00 115.97 ? 69  ASN A C   1 
ATOM 1093 O O   . ASN B 2 68  ? 111.630 73.587  118.968 1.00 119.89 ? 69  ASN A O   1 
ATOM 1094 C CB  . ASN B 2 68  ? 113.365 75.332  117.782 1.00 115.31 ? 69  ASN A CB  1 
ATOM 1095 C CG  . ASN B 2 68  ? 113.721 76.790  117.574 1.00 116.53 ? 69  ASN A CG  1 
ATOM 1096 O OD1 . ASN B 2 68  ? 114.494 77.368  118.337 1.00 117.18 ? 69  ASN A OD1 1 
ATOM 1097 N ND2 . ASN B 2 68  ? 113.157 77.393  116.533 1.00 109.21 ? 69  ASN A ND2 1 
ATOM 1098 N N   . ILE B 2 69  ? 112.907 73.137  120.750 1.00 111.85 ? 70  ILE A N   1 
ATOM 1099 C CA  . ILE B 2 69  ? 111.977 72.161  121.305 1.00 110.17 ? 70  ILE A CA  1 
ATOM 1100 C C   . ILE B 2 69  ? 111.001 72.888  122.218 1.00 113.17 ? 70  ILE A C   1 
ATOM 1101 O O   . ILE B 2 69  ? 111.412 73.625  123.122 1.00 111.97 ? 70  ILE A O   1 
ATOM 1102 C CB  . ILE B 2 69  ? 112.722 71.054  122.066 1.00 107.23 ? 70  ILE A CB  1 
ATOM 1103 C CG1 . ILE B 2 69  ? 113.838 70.470  121.201 1.00 109.49 ? 70  ILE A CG1 1 
ATOM 1104 C CG2 . ILE B 2 69  ? 111.755 69.965  122.493 1.00 108.47 ? 70  ILE A CG2 1 
ATOM 1105 C CD1 . ILE B 2 69  ? 114.379 69.154  121.712 1.00 107.49 ? 70  ILE A CD1 1 
ATOM 1106 N N   . THR B 2 70  ? 109.707 72.681  121.985 1.00 103.19 ? 71  THR A N   1 
ATOM 1107 C CA  . THR B 2 70  ? 108.662 73.337  122.759 1.00 100.98 ? 71  THR A CA  1 
ATOM 1108 C C   . THR B 2 70  ? 108.027 72.424  123.797 1.00 102.82 ? 71  THR A C   1 
ATOM 1109 O O   . THR B 2 70  ? 107.733 72.872  124.908 1.00 106.71 ? 71  THR A O   1 
ATOM 1110 C CB  . THR B 2 70  ? 107.572 73.875  121.828 1.00 103.28 ? 71  THR A CB  1 
ATOM 1111 O OG1 . THR B 2 70  ? 106.683 72.810  121.470 1.00 109.85 ? 71  THR A OG1 1 
ATOM 1112 C CG2 . THR B 2 70  ? 108.191 74.458  120.570 1.00 99.48  ? 71  THR A CG2 1 
ATOM 1113 N N   . GLN B 2 71  ? 107.798 71.158  123.463 1.00 90.92  ? 72  GLN A N   1 
ATOM 1114 C CA  . GLN B 2 71  ? 107.205 70.216  124.399 1.00 92.95  ? 72  GLN A CA  1 
ATOM 1115 C C   . GLN B 2 71  ? 107.895 68.867  124.271 1.00 94.90  ? 72  GLN A C   1 
ATOM 1116 O O   . GLN B 2 71  ? 108.170 68.403  123.162 1.00 99.74  ? 72  GLN A O   1 
ATOM 1117 C CB  . GLN B 2 71  ? 105.698 70.066  124.159 1.00 92.52  ? 72  GLN A CB  1 
ATOM 1118 C CG  . GLN B 2 71  ? 105.319 69.879  122.703 1.00 96.68  ? 72  GLN A CG  1 
ATOM 1119 C CD  . GLN B 2 71  ? 105.015 68.435  122.366 1.00 106.00 ? 72  GLN A CD  1 
ATOM 1120 O OE1 . GLN B 2 71  ? 104.668 67.643  123.241 1.00 107.03 ? 72  GLN A OE1 1 
ATOM 1121 N NE2 . GLN B 2 71  ? 105.149 68.083  121.093 1.00 105.39 ? 72  GLN A NE2 1 
ATOM 1122 N N   . LEU B 2 72  ? 108.170 68.244  125.414 1.00 92.08  ? 73  LEU A N   1 
ATOM 1123 C CA  . LEU B 2 72  ? 108.820 66.941  125.435 1.00 91.33  ? 73  LEU A CA  1 
ATOM 1124 C C   . LEU B 2 72  ? 107.766 65.845  125.456 1.00 92.95  ? 73  LEU A C   1 
ATOM 1125 O O   . LEU B 2 72  ? 107.018 65.742  126.437 1.00 91.09  ? 73  LEU A O   1 
ATOM 1126 C CB  . LEU B 2 72  ? 109.724 66.810  126.647 1.00 90.60  ? 73  LEU A CB  1 
ATOM 1127 C CG  . LEU B 2 72  ? 110.908 67.772  126.717 1.00 94.93  ? 73  LEU A CG  1 
ATOM 1128 C CD1 . LEU B 2 72  ? 111.687 67.563  128.001 1.00 96.26  ? 73  LEU A CD1 1 
ATOM 1129 C CD2 . LEU B 2 72  ? 111.808 67.595  125.510 1.00 95.77  ? 73  LEU A CD2 1 
ATOM 1130 N N   . PRO B 2 73  ? 107.671 65.015  124.422 1.00 107.49 ? 74  PRO A N   1 
ATOM 1131 C CA  . PRO B 2 73  ? 106.664 63.951  124.419 1.00 105.35 ? 74  PRO A CA  1 
ATOM 1132 C C   . PRO B 2 73  ? 106.959 62.900  125.477 1.00 108.86 ? 74  PRO A C   1 
ATOM 1133 O O   . PRO B 2 73  ? 108.043 62.846  126.061 1.00 118.67 ? 74  PRO A O   1 
ATOM 1134 C CB  . PRO B 2 73  ? 106.771 63.362  123.009 1.00 106.82 ? 74  PRO A CB  1 
ATOM 1135 C CG  . PRO B 2 73  ? 108.155 63.696  122.569 1.00 110.15 ? 74  PRO A CG  1 
ATOM 1136 C CD  . PRO B 2 73  ? 108.476 65.022  123.190 1.00 107.26 ? 74  PRO A CD  1 
ATOM 1137 N N   . GLU B 2 74  ? 105.934 62.081  125.738 1.00 116.65 ? 75  GLU A N   1 
ATOM 1138 C CA  . GLU B 2 74  ? 106.047 61.001  126.738 1.00 121.99 ? 75  GLU A CA  1 
ATOM 1139 C C   . GLU B 2 74  ? 107.210 60.082  126.381 1.00 126.19 ? 75  GLU A C   1 
ATOM 1140 O O   . GLU B 2 74  ? 107.355 59.751  125.185 1.00 124.85 ? 75  GLU A O   1 
ATOM 1141 C CB  . GLU B 2 74  ? 104.762 60.179  126.764 1.00 122.06 ? 75  GLU A CB  1 
ATOM 1142 C CG  . GLU B 2 74  ? 104.881 58.914  127.607 1.00 124.68 ? 75  GLU A CG  1 
ATOM 1143 C CD  . GLU B 2 74  ? 103.578 58.384  128.174 1.00 128.28 ? 75  GLU A CD  1 
ATOM 1144 O OE1 . GLU B 2 74  ? 102.498 58.748  127.665 1.00 130.95 ? 75  GLU A OE1 1 
ATOM 1145 O OE2 . GLU B 2 74  ? 103.652 57.586  129.129 1.00 127.04 ? 75  GLU A OE2 1 
ATOM 1146 N N   . ASP B 2 75  ? 108.006 59.696  127.369 1.00 131.51 ? 76  ASP A N   1 
ATOM 1147 C CA  . ASP B 2 75  ? 109.116 58.755  127.201 1.00 130.85 ? 76  ASP A CA  1 
ATOM 1148 C C   . ASP B 2 75  ? 110.067 59.204  126.095 1.00 130.00 ? 76  ASP A C   1 
ATOM 1149 O O   . ASP B 2 75  ? 110.550 58.396  125.299 1.00 129.68 ? 76  ASP A O   1 
ATOM 1150 C CB  . ASP B 2 75  ? 108.605 57.337  126.936 1.00 131.90 ? 76  ASP A CB  1 
ATOM 1151 C CG  . ASP B 2 75  ? 107.672 56.843  128.021 1.00 133.41 ? 76  ASP A CG  1 
ATOM 1152 O OD1 . ASP B 2 75  ? 107.644 57.459  129.107 1.00 134.02 ? 76  ASP A OD1 1 
ATOM 1153 O OD2 . ASP B 2 75  ? 106.966 55.839  127.789 1.00 134.58 ? 76  ASP A OD2 1 
ATOM 1154 N N   . ALA B 2 76  ? 110.334 60.510  126.041 1.00 129.13 ? 77  ALA A N   1 
ATOM 1155 C CA  . ALA B 2 76  ? 111.276 61.029  125.055 1.00 129.38 ? 77  ALA A CA  1 
ATOM 1156 C C   . ALA B 2 76  ? 112.695 60.557  125.342 1.00 131.94 ? 77  ALA A C   1 
ATOM 1157 O O   . ALA B 2 76  ? 113.456 60.260  124.415 1.00 132.40 ? 77  ALA A O   1 
ATOM 1158 C CB  . ALA B 2 76  ? 111.215 62.555  125.023 1.00 128.49 ? 77  ALA A CB  1 
ATOM 1159 N N   . PHE B 2 77  ? 113.068 60.482  126.618 1.00 132.38 ? 78  PHE A N   1 
ATOM 1160 C CA  . PHE B 2 77  ? 114.419 60.121  127.022 1.00 132.17 ? 78  PHE A CA  1 
ATOM 1161 C C   . PHE B 2 77  ? 114.535 58.670  127.467 1.00 134.11 ? 78  PHE A C   1 
ATOM 1162 O O   . PHE B 2 77  ? 115.526 58.307  128.108 1.00 136.47 ? 78  PHE A O   1 
ATOM 1163 C CB  . PHE B 2 77  ? 114.897 61.052  128.135 1.00 129.13 ? 78  PHE A CB  1 
ATOM 1164 C CG  . PHE B 2 77  ? 115.136 62.459  127.680 1.00 127.31 ? 78  PHE A CG  1 
ATOM 1165 C CD1 . PHE B 2 77  ? 115.663 62.714  126.427 1.00 129.83 ? 78  PHE A CD1 1 
ATOM 1166 C CD2 . PHE B 2 77  ? 114.828 63.528  128.500 1.00 125.96 ? 78  PHE A CD2 1 
ATOM 1167 C CE1 . PHE B 2 77  ? 115.884 64.008  126.003 1.00 129.54 ? 78  PHE A CE1 1 
ATOM 1168 C CE2 . PHE B 2 77  ? 115.045 64.824  128.080 1.00 127.69 ? 78  PHE A CE2 1 
ATOM 1169 C CZ  . PHE B 2 77  ? 115.574 65.064  126.831 1.00 129.27 ? 78  PHE A CZ  1 
ATOM 1170 N N   . LYS B 2 78  ? 113.547 57.832  127.148 1.00 138.40 ? 79  LYS A N   1 
ATOM 1171 C CA  . LYS B 2 78  ? 113.623 56.417  127.489 1.00 137.52 ? 79  LYS A CA  1 
ATOM 1172 C C   . LYS B 2 78  ? 114.709 55.682  126.715 1.00 138.79 ? 79  LYS A C   1 
ATOM 1173 O O   . LYS B 2 78  ? 115.038 54.546  127.075 1.00 137.65 ? 79  LYS A O   1 
ATOM 1174 C CB  . LYS B 2 78  ? 112.273 55.743  127.245 1.00 133.96 ? 79  LYS A CB  1 
ATOM 1175 N N   . ASN B 2 79  ? 115.267 56.292  125.670 1.00 141.65 ? 80  ASN A N   1 
ATOM 1176 C CA  . ASN B 2 79  ? 116.299 55.641  124.875 1.00 143.45 ? 80  ASN A CA  1 
ATOM 1177 C C   . ASN B 2 79  ? 117.684 55.746  125.501 1.00 142.78 ? 80  ASN A C   1 
ATOM 1178 O O   . ASN B 2 79  ? 118.601 55.047  125.057 1.00 143.96 ? 80  ASN A O   1 
ATOM 1179 C CB  . ASN B 2 79  ? 116.329 56.237  123.466 1.00 141.24 ? 80  ASN A CB  1 
ATOM 1180 C CG  . ASN B 2 79  ? 116.965 55.307  122.455 1.00 141.99 ? 80  ASN A CG  1 
ATOM 1181 O OD1 . ASN B 2 79  ? 117.129 54.114  122.708 1.00 141.91 ? 80  ASN A OD1 1 
ATOM 1182 N ND2 . ASN B 2 79  ? 117.331 55.850  121.300 1.00 141.72 ? 80  ASN A ND2 1 
ATOM 1183 N N   . PHE B 2 80  ? 117.860 56.594  126.513 1.00 135.27 ? 81  PHE A N   1 
ATOM 1184 C CA  . PHE B 2 80  ? 119.157 56.809  127.157 1.00 135.12 ? 81  PHE A CA  1 
ATOM 1185 C C   . PHE B 2 80  ? 119.010 56.590  128.656 1.00 138.42 ? 81  PHE A C   1 
ATOM 1186 O O   . PHE B 2 80  ? 118.922 57.551  129.432 1.00 138.35 ? 81  PHE A O   1 
ATOM 1187 C CB  . PHE B 2 80  ? 119.702 58.208  126.862 1.00 133.09 ? 81  PHE A CB  1 
ATOM 1188 C CG  . PHE B 2 80  ? 119.372 58.715  125.488 1.00 135.26 ? 81  PHE A CG  1 
ATOM 1189 C CD1 . PHE B 2 80  ? 119.744 58.001  124.362 1.00 138.72 ? 81  PHE A CD1 1 
ATOM 1190 C CD2 . PHE B 2 80  ? 118.693 59.908  125.322 1.00 136.78 ? 81  PHE A CD2 1 
ATOM 1191 C CE1 . PHE B 2 80  ? 119.440 58.466  123.098 1.00 138.57 ? 81  PHE A CE1 1 
ATOM 1192 C CE2 . PHE B 2 80  ? 118.388 60.379  124.060 1.00 138.23 ? 81  PHE A CE2 1 
ATOM 1193 C CZ  . PHE B 2 80  ? 118.762 59.657  122.947 1.00 138.18 ? 81  PHE A CZ  1 
ATOM 1194 N N   . PRO B 2 81  ? 118.982 55.330  129.102 1.00 147.93 ? 82  PRO A N   1 
ATOM 1195 C CA  . PRO B 2 81  ? 118.871 55.059  130.541 1.00 147.67 ? 82  PRO A CA  1 
ATOM 1196 C C   . PRO B 2 81  ? 120.143 55.334  131.325 1.00 146.42 ? 82  PRO A C   1 
ATOM 1197 O O   . PRO B 2 81  ? 120.093 55.345  132.562 1.00 144.46 ? 82  PRO A O   1 
ATOM 1198 C CB  . PRO B 2 81  ? 118.516 53.568  130.586 1.00 145.28 ? 82  PRO A CB  1 
ATOM 1199 C CG  . PRO B 2 81  ? 119.113 53.008  129.344 1.00 144.27 ? 82  PRO A CG  1 
ATOM 1200 C CD  . PRO B 2 81  ? 119.056 54.094  128.304 1.00 144.64 ? 82  PRO A CD  1 
ATOM 1201 N N   . PHE B 2 82  ? 121.273 55.554  130.656 1.00 149.76 ? 83  PHE A N   1 
ATOM 1202 C CA  . PHE B 2 82  ? 122.546 55.794  131.321 1.00 148.48 ? 83  PHE A CA  1 
ATOM 1203 C C   . PHE B 2 82  ? 122.889 57.274  131.404 1.00 146.46 ? 83  PHE A C   1 
ATOM 1204 O O   . PHE B 2 82  ? 124.031 57.621  131.721 1.00 144.04 ? 83  PHE A O   1 
ATOM 1205 C CB  . PHE B 2 82  ? 123.664 55.039  130.600 1.00 146.84 ? 83  PHE A CB  1 
ATOM 1206 C CG  . PHE B 2 82  ? 123.792 53.604  131.018 1.00 146.42 ? 83  PHE A CG  1 
ATOM 1207 C CD1 . PHE B 2 82  ? 122.844 53.021  131.842 1.00 145.46 ? 83  PHE A CD1 1 
ATOM 1208 C CD2 . PHE B 2 82  ? 124.858 52.835  130.583 1.00 146.57 ? 83  PHE A CD2 1 
ATOM 1209 C CE1 . PHE B 2 82  ? 122.957 51.700  132.226 1.00 146.26 ? 83  PHE A CE1 1 
ATOM 1210 C CE2 . PHE B 2 82  ? 124.977 51.513  130.964 1.00 147.61 ? 83  PHE A CE2 1 
ATOM 1211 C CZ  . PHE B 2 82  ? 124.025 50.945  131.787 1.00 147.20 ? 83  PHE A CZ  1 
ATOM 1212 N N   . LEU B 2 83  ? 121.909 58.139  131.150 1.00 133.37 ? 84  LEU A N   1 
ATOM 1213 C CA  . LEU B 2 83  ? 122.174 59.594  131.132 1.00 133.82 ? 84  LEU A CA  1 
ATOM 1214 C C   . LEU B 2 83  ? 122.545 60.032  132.547 1.00 133.49 ? 84  LEU A C   1 
ATOM 1215 O O   . LEU B 2 83  ? 122.026 59.434  133.501 1.00 131.96 ? 84  LEU A O   1 
ATOM 1216 C CB  . LEU B 2 83  ? 120.993 60.386  130.582 1.00 130.60 ? 84  LEU A CB  1 
ATOM 1217 C CG  . LEU B 2 83  ? 121.364 61.530  129.639 1.00 129.75 ? 84  LEU A CG  1 
ATOM 1218 C CD1 . LEU B 2 83  ? 120.556 61.497  128.360 1.00 130.85 ? 84  LEU A CD1 1 
ATOM 1219 C CD2 . LEU B 2 83  ? 121.186 62.836  130.365 1.00 129.89 ? 84  LEU A CD2 1 
ATOM 1220 N N   . GLU B 2 84  ? 123.416 61.021  132.662 1.00 131.54 ? 85  GLU A N   1 
ATOM 1221 C CA  . GLU B 2 84  ? 123.887 61.548  133.967 1.00 129.30 ? 85  GLU A CA  1 
ATOM 1222 C C   . GLU B 2 84  ? 123.952 63.074  134.006 1.00 128.18 ? 85  GLU A C   1 
ATOM 1223 O O   . GLU B 2 84  ? 124.178 63.576  135.097 1.00 129.96 ? 85  GLU A O   1 
ATOM 1224 C CB  . GLU B 2 84  ? 125.285 60.994  134.151 1.00 129.58 ? 85  GLU A CB  1 
ATOM 1225 C CG  . GLU B 2 84  ? 125.570 60.529  135.574 1.00 132.70 ? 85  GLU A CG  1 
ATOM 1226 C CD  . GLU B 2 84  ? 127.034 60.220  135.813 1.00 133.78 ? 85  GLU A CD  1 
ATOM 1227 O OE1 . GLU B 2 84  ? 127.638 59.535  134.961 1.00 134.32 ? 85  GLU A OE1 1 
ATOM 1228 O OE2 . GLU B 2 84  ? 127.575 60.666  136.843 1.00 132.94 ? 85  GLU A OE2 1 
ATOM 1229 N N   . GLU B 2 85  ? 124.010 63.777  132.888 1.00 121.19 ? 86  GLU A N   1 
ATOM 1230 C CA  . GLU B 2 85  ? 123.862 65.224  132.837 1.00 120.06 ? 86  GLU A CA  1 
ATOM 1231 C C   . GLU B 2 85  ? 123.064 65.599  131.599 1.00 121.94 ? 86  GLU A C   1 
ATOM 1232 O O   . GLU B 2 85  ? 123.393 65.165  130.491 1.00 127.51 ? 86  GLU A O   1 
ATOM 1233 C CB  . GLU B 2 85  ? 125.222 65.925  132.818 1.00 120.22 ? 86  GLU A CB  1 
ATOM 1234 C CG  . GLU B 2 85  ? 125.127 67.439  132.815 1.00 123.53 ? 86  GLU A CG  1 
ATOM 1235 C CD  . GLU B 2 85  ? 126.039 68.080  131.792 1.00 127.57 ? 86  GLU A CD  1 
ATOM 1236 O OE1 . GLU B 2 85  ? 126.796 67.344  131.125 1.00 126.28 ? 86  GLU A OE1 1 
ATOM 1237 O OE2 . GLU B 2 85  ? 126.000 69.320  131.653 1.00 129.20 ? 86  GLU A OE2 1 
ATOM 1238 N N   . LEU B 2 86  ? 122.025 66.407  131.788 1.00 104.05 ? 87  LEU A N   1 
ATOM 1239 C CA  . LEU B 2 86  ? 121.142 66.818  130.705 1.00 97.56  ? 87  LEU A CA  1 
ATOM 1240 C C   . LEU B 2 86  ? 120.943 68.323  130.770 1.00 94.04  ? 87  LEU A C   1 
ATOM 1241 O O   . LEU B 2 86  ? 120.707 68.873  131.850 1.00 100.66 ? 87  LEU A O   1 
ATOM 1242 C CB  . LEU B 2 86  ? 119.793 66.100  130.795 1.00 97.63  ? 87  LEU A CB  1 
ATOM 1243 C CG  . LEU B 2 86  ? 118.650 66.686  129.972 1.00 94.71  ? 87  LEU A CG  1 
ATOM 1244 C CD1 . LEU B 2 86  ? 118.885 66.438  128.496 1.00 102.56 ? 87  LEU A CD1 1 
ATOM 1245 C CD2 . LEU B 2 86  ? 117.329 66.090  130.413 1.00 98.01  ? 87  LEU A CD2 1 
ATOM 1246 N N   . GLN B 2 87  ? 121.035 68.984  129.619 1.00 88.62  ? 88  GLN A N   1 
ATOM 1247 C CA  . GLN B 2 87  ? 120.894 70.432  129.536 1.00 91.76  ? 88  GLN A CA  1 
ATOM 1248 C C   . GLN B 2 87  ? 119.822 70.771  128.514 1.00 93.59  ? 88  GLN A C   1 
ATOM 1249 O O   . GLN B 2 87  ? 119.933 70.386  127.346 1.00 103.29 ? 88  GLN A O   1 
ATOM 1250 C CB  . GLN B 2 87  ? 122.219 71.096  129.157 1.00 93.59  ? 88  GLN A CB  1 
ATOM 1251 C CG  . GLN B 2 87  ? 123.389 70.692  130.029 1.00 96.60  ? 88  GLN A CG  1 
ATOM 1252 C CD  . GLN B 2 87  ? 124.455 71.763  130.091 1.00 102.74 ? 88  GLN A CD  1 
ATOM 1253 O OE1 . GLN B 2 87  ? 124.498 72.660  129.250 1.00 101.15 ? 88  GLN A OE1 1 
ATOM 1254 N NE2 . GLN B 2 87  ? 125.320 71.681  131.095 1.00 105.58 ? 88  GLN A NE2 1 
ATOM 1255 N N   . LEU B 2 88  ? 118.792 71.492  128.952 1.00 82.79  ? 89  LEU A N   1 
ATOM 1256 C CA  . LEU B 2 88  ? 117.740 72.002  128.072 1.00 82.14  ? 89  LEU A CA  1 
ATOM 1257 C C   . LEU B 2 88  ? 117.592 73.489  128.375 1.00 90.89  ? 89  LEU A C   1 
ATOM 1258 O O   . LEU B 2 88  ? 116.735 73.887  129.165 1.00 102.29 ? 89  LEU A O   1 
ATOM 1259 C CB  . LEU B 2 88  ? 116.431 71.250  128.279 1.00 83.02  ? 89  LEU A CB  1 
ATOM 1260 C CG  . LEU B 2 88  ? 116.508 69.724  128.303 1.00 85.98  ? 89  LEU A CG  1 
ATOM 1261 C CD1 . LEU B 2 88  ? 115.206 69.124  128.798 1.00 86.18  ? 89  LEU A CD1 1 
ATOM 1262 C CD2 . LEU B 2 88  ? 116.842 69.199  126.926 1.00 92.81  ? 89  LEU A CD2 1 
ATOM 1263 N N   . ALA B 2 89  ? 118.419 74.308  127.733 1.00 97.68  ? 90  ALA A N   1 
ATOM 1264 C CA  . ALA B 2 89  ? 118.410 75.746  127.938 1.00 95.64  ? 90  ALA A CA  1 
ATOM 1265 C C   . ALA B 2 89  ? 118.181 76.441  126.605 1.00 101.06 ? 90  ALA A C   1 
ATOM 1266 O O   . ALA B 2 89  ? 118.433 75.879  125.538 1.00 116.44 ? 90  ALA A O   1 
ATOM 1267 C CB  . ALA B 2 89  ? 119.718 76.234  128.568 1.00 95.52  ? 90  ALA A CB  1 
ATOM 1268 N N   . GLY B 2 90  ? 117.679 77.672  126.672 1.00 95.40  ? 91  GLY A N   1 
ATOM 1269 C CA  . GLY B 2 90  ? 117.426 78.450  125.481 1.00 100.50 ? 91  GLY A CA  1 
ATOM 1270 C C   . GLY B 2 90  ? 116.224 78.016  124.677 1.00 101.91 ? 91  GLY A C   1 
ATOM 1271 O O   . GLY B 2 90  ? 115.694 78.819  123.900 1.00 109.51 ? 91  GLY A O   1 
ATOM 1272 N N   . ASN B 2 91  ? 115.779 76.774  124.832 1.00 95.55  ? 92  ASN A N   1 
ATOM 1273 C CA  . ASN B 2 91  ? 114.624 76.285  124.100 1.00 98.74  ? 92  ASN A CA  1 
ATOM 1274 C C   . ASN B 2 91  ? 113.371 77.040  124.520 1.00 107.54 ? 92  ASN A C   1 
ATOM 1275 O O   . ASN B 2 91  ? 113.230 77.466  125.669 1.00 112.87 ? 92  ASN A O   1 
ATOM 1276 C CB  . ASN B 2 91  ? 114.428 74.789  124.344 1.00 93.59  ? 92  ASN A CB  1 
ATOM 1277 C CG  . ASN B 2 91  ? 115.428 73.936  123.593 1.00 103.63 ? 92  ASN A CG  1 
ATOM 1278 O OD1 . ASN B 2 91  ? 115.129 72.807  123.210 1.00 107.21 ? 92  ASN A OD1 1 
ATOM 1279 N ND2 . ASN B 2 91  ? 116.623 74.469  123.381 1.00 110.79 ? 92  ASN A ND2 1 
ATOM 1280 N N   . ASP B 2 92  ? 112.453 77.207  123.571 1.00 108.01 ? 93  ASP A N   1 
ATOM 1281 C CA  . ASP B 2 92  ? 111.155 77.785  123.886 1.00 107.58 ? 93  ASP A CA  1 
ATOM 1282 C C   . ASP B 2 92  ? 110.243 76.695  124.432 1.00 107.29 ? 93  ASP A C   1 
ATOM 1283 O O   . ASP B 2 92  ? 109.124 76.507  123.946 1.00 106.26 ? 93  ASP A O   1 
ATOM 1284 C CB  . ASP B 2 92  ? 110.540 78.440  122.649 1.00 112.69 ? 93  ASP A CB  1 
ATOM 1285 C CG  . ASP B 2 92  ? 110.083 79.859  122.911 1.00 113.49 ? 93  ASP A CG  1 
ATOM 1286 O OD1 . ASP B 2 92  ? 110.263 80.341  124.048 1.00 107.50 ? 93  ASP A OD1 1 
ATOM 1287 O OD2 . ASP B 2 92  ? 109.541 80.493  121.981 1.00 114.72 ? 93  ASP A OD2 1 
ATOM 1288 N N   . LEU B 2 93  ? 110.719 75.974  125.442 1.00 98.28  ? 94  LEU A N   1 
ATOM 1289 C CA  . LEU B 2 93  ? 110.013 74.822  125.981 1.00 92.48  ? 94  LEU A CA  1 
ATOM 1290 C C   . LEU B 2 93  ? 109.026 75.277  127.046 1.00 93.06  ? 94  LEU A C   1 
ATOM 1291 O O   . LEU B 2 93  ? 109.394 76.003  127.975 1.00 94.57  ? 94  LEU A O   1 
ATOM 1292 C CB  . LEU B 2 93  ? 111.008 73.811  126.553 1.00 92.49  ? 94  LEU A CB  1 
ATOM 1293 C CG  . LEU B 2 93  ? 110.512 72.672  127.442 1.00 90.64  ? 94  LEU A CG  1 
ATOM 1294 C CD1 . LEU B 2 93  ? 111.242 71.395  127.088 1.00 89.33  ? 94  LEU A CD1 1 
ATOM 1295 C CD2 . LEU B 2 93  ? 110.742 73.007  128.899 1.00 93.78  ? 94  LEU A CD2 1 
ATOM 1296 N N   . SER B 2 94  ? 107.770 74.852  126.902 1.00 89.93  ? 95  SER A N   1 
ATOM 1297 C CA  . SER B 2 94  ? 106.721 75.286  127.815 1.00 87.56  ? 95  SER A CA  1 
ATOM 1298 C C   . SER B 2 94  ? 105.775 74.155  128.201 1.00 88.08  ? 95  SER A C   1 
ATOM 1299 O O   . SER B 2 94  ? 104.630 74.424  128.582 1.00 99.39  ? 95  SER A O   1 
ATOM 1300 C CB  . SER B 2 94  ? 105.924 76.434  127.199 1.00 94.21  ? 95  SER A CB  1 
ATOM 1301 O OG  . SER B 2 94  ? 105.237 76.001  126.041 1.00 101.90 ? 95  SER A OG  1 
ATOM 1302 N N   . PHE B 2 95  ? 106.217 72.902  128.112 1.00 81.93  ? 96  PHE A N   1 
ATOM 1303 C CA  . PHE B 2 95  ? 105.400 71.768  128.524 1.00 83.80  ? 96  PHE A CA  1 
ATOM 1304 C C   . PHE B 2 95  ? 106.291 70.541  128.624 1.00 93.54  ? 96  PHE A C   1 
ATOM 1305 O O   . PHE B 2 95  ? 107.079 70.274  127.713 1.00 107.73 ? 96  PHE A O   1 
ATOM 1306 C CB  . PHE B 2 95  ? 104.258 71.513  127.537 1.00 82.54  ? 96  PHE A CB  1 
ATOM 1307 C CG  . PHE B 2 95  ? 103.443 70.299  127.862 1.00 81.71  ? 96  PHE A CG  1 
ATOM 1308 C CD1 . PHE B 2 95  ? 102.828 70.175  129.093 1.00 85.14  ? 96  PHE A CD1 1 
ATOM 1309 C CD2 . PHE B 2 95  ? 103.298 69.280  126.940 1.00 87.43  ? 96  PHE A CD2 1 
ATOM 1310 C CE1 . PHE B 2 95  ? 102.079 69.058  129.397 1.00 93.18  ? 96  PHE A CE1 1 
ATOM 1311 C CE2 . PHE B 2 95  ? 102.550 68.161  127.239 1.00 89.38  ? 96  PHE A CE2 1 
ATOM 1312 C CZ  . PHE B 2 95  ? 101.940 68.050  128.469 1.00 94.14  ? 96  PHE A CZ  1 
ATOM 1313 N N   . ILE B 2 96  ? 106.166 69.804  129.723 1.00 93.31  ? 97  ILE A N   1 
ATOM 1314 C CA  . ILE B 2 96  ? 106.918 68.574  129.940 1.00 85.18  ? 97  ILE A CA  1 
ATOM 1315 C C   . ILE B 2 96  ? 105.926 67.482  130.308 1.00 89.96  ? 97  ILE A C   1 
ATOM 1316 O O   . ILE B 2 96  ? 105.205 67.606  131.304 1.00 103.97 ? 97  ILE A O   1 
ATOM 1317 C CB  . ILE B 2 96  ? 107.980 68.730  131.039 1.00 80.74  ? 97  ILE A CB  1 
ATOM 1318 C CG1 . ILE B 2 96  ? 108.980 69.824  130.666 1.00 80.46  ? 97  ILE A CG1 1 
ATOM 1319 C CG2 . ILE B 2 96  ? 108.695 67.415  131.274 1.00 87.78  ? 97  ILE A CG2 1 
ATOM 1320 C CD1 . ILE B 2 96  ? 110.046 70.053  131.710 1.00 85.85  ? 97  ILE A CD1 1 
ATOM 1321 N N   . HIS B 2 97  ? 105.869 66.429  129.481 1.00 93.67  ? 98  HIS A N   1 
ATOM 1322 C CA  . HIS B 2 97  ? 104.950 65.291  129.735 1.00 94.75  ? 98  HIS A CA  1 
ATOM 1323 C C   . HIS B 2 97  ? 105.327 64.698  131.093 1.00 99.25  ? 98  HIS A C   1 
ATOM 1324 O O   . HIS B 2 97  ? 106.507 64.750  131.478 1.00 110.92 ? 98  HIS A O   1 
ATOM 1325 C CB  . HIS B 2 97  ? 104.994 64.233  128.631 1.00 102.27 ? 98  HIS A CB  1 
ATOM 1326 C CG  . HIS B 2 97  ? 103.783 63.370  128.674 1.00 103.20 ? 98  HIS A CG  1 
ATOM 1327 N ND1 . HIS B 2 97  ? 103.757 62.154  129.318 1.00 99.94  ? 98  HIS A ND1 1 
ATOM 1328 C CD2 . HIS B 2 97  ? 102.544 63.572  128.215 1.00 106.12 ? 98  HIS A CD2 1 
ATOM 1329 C CE1 . HIS B 2 97  ? 102.543 61.637  129.228 1.00 100.83 ? 98  HIS A CE1 1 
ATOM 1330 N NE2 . HIS B 2 97  ? 101.791 62.479  128.556 1.00 103.69 ? 98  HIS A NE2 1 
ATOM 1331 N N   . PRO B 2 98  ? 104.360 64.203  131.887 1.00 96.81  ? 99  PRO A N   1 
ATOM 1332 C CA  . PRO B 2 98  ? 104.687 63.581  133.181 1.00 104.50 ? 99  PRO A CA  1 
ATOM 1333 C C   . PRO B 2 98  ? 105.626 62.392  133.078 1.00 109.66 ? 99  PRO A C   1 
ATOM 1334 O O   . PRO B 2 98  ? 106.469 62.199  133.962 1.00 107.68 ? 99  PRO A O   1 
ATOM 1335 C CB  . PRO B 2 98  ? 103.310 63.174  133.718 1.00 107.12 ? 99  PRO A CB  1 
ATOM 1336 C CG  . PRO B 2 98  ? 102.383 64.165  133.117 1.00 104.95 ? 99  PRO A CG  1 
ATOM 1337 C CD  . PRO B 2 98  ? 102.915 64.452  131.744 1.00 98.65  ? 99  PRO A CD  1 
ATOM 1338 N N   . LYS B 2 99  ? 105.509 61.588  132.026 1.00 115.63 ? 100 LYS A N   1 
ATOM 1339 C CA  . LYS B 2 99  ? 106.364 60.423  131.848 1.00 113.57 ? 100 LYS A CA  1 
ATOM 1340 C C   . LYS B 2 99  ? 107.574 60.702  130.968 1.00 113.12 ? 100 LYS A C   1 
ATOM 1341 O O   . LYS B 2 99  ? 108.340 59.775  130.684 1.00 117.57 ? 100 LYS A O   1 
ATOM 1342 C CB  . LYS B 2 99  ? 105.557 59.263  131.257 1.00 113.17 ? 100 LYS A CB  1 
ATOM 1343 C CG  . LYS B 2 99  ? 104.332 58.874  132.071 1.00 112.99 ? 100 LYS A CG  1 
ATOM 1344 C CD  . LYS B 2 99  ? 104.649 58.795  133.555 1.00 113.91 ? 100 LYS A CD  1 
ATOM 1345 C CE  . LYS B 2 99  ? 105.069 57.392  133.957 1.00 114.81 ? 100 LYS A CE  1 
ATOM 1346 N NZ  . LYS B 2 99  ? 105.499 57.330  135.382 1.00 116.19 ? 100 LYS A NZ  1 
ATOM 1347 N N   . ALA B 2 100 ? 107.762 61.947  130.526 1.00 110.61 ? 101 ALA A N   1 
ATOM 1348 C CA  . ALA B 2 100 ? 108.881 62.258  129.642 1.00 111.01 ? 101 ALA A CA  1 
ATOM 1349 C C   . ALA B 2 100 ? 110.218 62.048  130.338 1.00 111.75 ? 101 ALA A C   1 
ATOM 1350 O O   . ALA B 2 100 ? 111.153 61.493  129.749 1.00 112.23 ? 101 ALA A O   1 
ATOM 1351 C CB  . ALA B 2 100 ? 108.764 63.695  129.135 1.00 116.16 ? 101 ALA A CB  1 
ATOM 1352 N N   . LEU B 2 101 ? 110.363 62.480  131.587 1.00 106.88 ? 102 LEU A N   1 
ATOM 1353 C CA  . LEU B 2 101 ? 111.668 62.374  132.282 1.00 109.22 ? 102 LEU A CA  1 
ATOM 1354 C C   . LEU B 2 101 ? 111.689 61.103  133.140 1.00 114.23 ? 102 LEU A C   1 
ATOM 1355 O O   . LEU B 2 101 ? 112.652 60.950  133.893 1.00 119.15 ? 102 LEU A O   1 
ATOM 1356 C CB  . LEU B 2 101 ? 111.935 63.611  133.128 1.00 105.90 ? 102 LEU A CB  1 
ATOM 1357 C CG  . LEU B 2 101 ? 112.334 64.895  132.404 1.00 107.12 ? 102 LEU A CG  1 
ATOM 1358 C CD1 . LEU B 2 101 ? 112.697 65.903  133.468 1.00 104.76 ? 102 LEU A CD1 1 
ATOM 1359 C CD2 . LEU B 2 101 ? 113.482 64.718  131.448 1.00 110.97 ? 102 LEU A CD2 1 
ATOM 1360 N N   . SER B 2 102 ? 110.705 60.208  133.050 1.00 120.88 ? 103 SER A N   1 
ATOM 1361 C CA  . SER B 2 102 ? 110.755 58.961  133.797 1.00 119.46 ? 103 SER A CA  1 
ATOM 1362 C C   . SER B 2 102 ? 111.844 58.046  133.249 1.00 121.49 ? 103 SER A C   1 
ATOM 1363 O O   . SER B 2 102 ? 112.196 58.098  132.067 1.00 119.08 ? 103 SER A O   1 
ATOM 1364 C CB  . SER B 2 102 ? 109.403 58.251  133.744 1.00 117.34 ? 103 SER A CB  1 
ATOM 1365 O OG  . SER B 2 102 ? 109.361 57.320  132.677 1.00 122.46 ? 103 SER A OG  1 
ATOM 1366 N N   . GLY B 2 103 ? 112.378 57.200  134.126 1.00 129.69 ? 104 GLY A N   1 
ATOM 1367 C CA  . GLY B 2 103 ? 113.416 56.263  133.755 1.00 129.96 ? 104 GLY A CA  1 
ATOM 1368 C C   . GLY B 2 103 ? 114.824 56.812  133.790 1.00 132.36 ? 104 GLY A C   1 
ATOM 1369 O O   . GLY B 2 103 ? 115.768 56.063  133.507 1.00 133.03 ? 104 GLY A O   1 
ATOM 1370 N N   . LEU B 2 104 ? 115.001 58.087  134.127 1.00 130.80 ? 105 LEU A N   1 
ATOM 1371 C CA  . LEU B 2 104 ? 116.329 58.694  134.190 1.00 128.78 ? 105 LEU A CA  1 
ATOM 1372 C C   . LEU B 2 104 ? 116.841 58.653  135.629 1.00 128.61 ? 105 LEU A C   1 
ATOM 1373 O O   . LEU B 2 104 ? 117.010 59.670  136.301 1.00 125.21 ? 105 LEU A O   1 
ATOM 1374 C CB  . LEU B 2 104 ? 116.286 60.117  133.644 1.00 126.91 ? 105 LEU A CB  1 
ATOM 1375 C CG  . LEU B 2 104 ? 116.737 60.307  132.195 1.00 128.16 ? 105 LEU A CG  1 
ATOM 1376 C CD1 . LEU B 2 104 ? 116.164 59.224  131.296 1.00 126.55 ? 105 LEU A CD1 1 
ATOM 1377 C CD2 . LEU B 2 104 ? 116.336 61.682  131.692 1.00 129.62 ? 105 LEU A CD2 1 
ATOM 1378 N N   . LYS B 2 105 ? 117.083 57.426  136.095 1.00 133.56 ? 106 LYS A N   1 
ATOM 1379 C CA  . LYS B 2 105 ? 117.538 57.231  137.468 1.00 132.95 ? 106 LYS A CA  1 
ATOM 1380 C C   . LYS B 2 105 ? 118.927 57.800  137.728 1.00 134.86 ? 106 LYS A C   1 
ATOM 1381 O O   . LYS B 2 105 ? 119.183 58.359  138.800 1.00 136.60 ? 106 LYS A O   1 
ATOM 1382 C CB  . LYS B 2 105 ? 117.494 55.747  137.827 1.00 129.74 ? 106 LYS A CB  1 
ATOM 1383 C CG  . LYS B 2 105 ? 116.158 55.077  137.550 1.00 129.75 ? 106 LYS A CG  1 
ATOM 1384 C CD  . LYS B 2 105 ? 115.033 55.739  138.329 1.00 133.04 ? 106 LYS A CD  1 
ATOM 1385 C CE  . LYS B 2 105 ? 113.978 56.313  137.398 1.00 134.91 ? 106 LYS A CE  1 
ATOM 1386 N NZ  . LYS B 2 105 ? 112.958 57.107  138.137 1.00 135.59 ? 106 LYS A NZ  1 
ATOM 1387 N N   . GLU B 2 106 ? 119.836 57.670  136.764 1.00 136.30 ? 107 GLU A N   1 
ATOM 1388 C CA  . GLU B 2 106 ? 121.217 58.090  136.956 1.00 134.19 ? 107 GLU A CA  1 
ATOM 1389 C C   . GLU B 2 106 ? 121.449 59.562  136.627 1.00 132.89 ? 107 GLU A C   1 
ATOM 1390 O O   . GLU B 2 106 ? 122.593 60.023  136.684 1.00 134.92 ? 107 GLU A O   1 
ATOM 1391 C CB  . GLU B 2 106 ? 122.152 57.256  136.078 1.00 135.62 ? 107 GLU A CB  1 
ATOM 1392 C CG  . GLU B 2 106 ? 122.239 55.794  136.481 1.00 136.83 ? 107 GLU A CG  1 
ATOM 1393 C CD  . GLU B 2 106 ? 123.116 54.984  135.547 1.00 142.10 ? 107 GLU A CD  1 
ATOM 1394 O OE1 . GLU B 2 106 ? 123.502 55.514  134.483 1.00 140.43 ? 107 GLU A OE1 1 
ATOM 1395 O OE2 . GLU B 2 106 ? 123.423 53.820  135.879 1.00 143.34 ? 107 GLU A OE2 1 
ATOM 1396 N N   . LEU B 2 107 ? 120.399 60.303  136.277 1.00 110.73 ? 108 LEU A N   1 
ATOM 1397 C CA  . LEU B 2 107 ? 120.562 61.715  135.960 1.00 112.06 ? 108 LEU A CA  1 
ATOM 1398 C C   . LEU B 2 107 ? 120.989 62.432  137.235 1.00 112.63 ? 108 LEU A C   1 
ATOM 1399 O O   . LEU B 2 107 ? 120.497 62.139  138.327 1.00 113.44 ? 108 LEU A O   1 
ATOM 1400 C CB  . LEU B 2 107 ? 119.260 62.319  135.435 1.00 112.08 ? 108 LEU A CB  1 
ATOM 1401 C CG  . LEU B 2 107 ? 119.365 63.738  134.875 1.00 112.19 ? 108 LEU A CG  1 
ATOM 1402 C CD1 . LEU B 2 107 ? 118.653 63.839  133.540 1.00 112.54 ? 108 LEU A CD1 1 
ATOM 1403 C CD2 . LEU B 2 107 ? 118.803 64.749  135.859 1.00 112.57 ? 108 LEU A CD2 1 
ATOM 1404 N N   . LYS B 2 108 ? 121.914 63.377  137.089 1.00 104.86 ? 109 LYS A N   1 
ATOM 1405 C CA  . LYS B 2 108 ? 122.428 64.142  138.215 1.00 100.77 ? 109 LYS A CA  1 
ATOM 1406 C C   . LYS B 2 108 ? 122.299 65.647  138.052 1.00 103.89 ? 109 LYS A C   1 
ATOM 1407 O O   . LYS B 2 108 ? 122.089 66.341  139.049 1.00 110.81 ? 109 LYS A O   1 
ATOM 1408 C CB  . LYS B 2 108 ? 123.907 63.813  138.467 1.00 105.32 ? 109 LYS A CB  1 
ATOM 1409 C CG  . LYS B 2 108 ? 124.159 62.380  138.903 1.00 107.32 ? 109 LYS A CG  1 
ATOM 1410 C CD  . LYS B 2 108 ? 125.639 62.124  139.134 1.00 105.93 ? 109 LYS A CD  1 
ATOM 1411 C CE  . LYS B 2 108 ? 125.896 60.677  139.524 1.00 108.29 ? 109 LYS A CE  1 
ATOM 1412 N NZ  . LYS B 2 108 ? 125.241 60.329  140.813 1.00 107.25 ? 109 LYS A NZ  1 
ATOM 1413 N N   . VAL B 2 109 ? 122.420 66.169  136.835 1.00 89.91  ? 110 VAL A N   1 
ATOM 1414 C CA  . VAL B 2 109 ? 122.323 67.600  136.572 1.00 88.72  ? 110 VAL A CA  1 
ATOM 1415 C C   . VAL B 2 109 ? 121.241 67.819  135.526 1.00 90.65  ? 110 VAL A C   1 
ATOM 1416 O O   . VAL B 2 109 ? 121.264 67.191  134.462 1.00 101.98 ? 110 VAL A O   1 
ATOM 1417 C CB  . VAL B 2 109 ? 123.660 68.201  136.105 1.00 89.83  ? 110 VAL A CB  1 
ATOM 1418 C CG1 . VAL B 2 109 ? 123.471 69.646  135.684 1.00 90.51  ? 110 VAL A CG1 1 
ATOM 1419 C CG2 . VAL B 2 109 ? 124.697 68.096  137.206 1.00 95.51  ? 110 VAL A CG2 1 
ATOM 1420 N N   . LEU B 2 110 ? 120.298 68.708  135.829 1.00 78.84  ? 111 LEU A N   1 
ATOM 1421 C CA  . LEU B 2 110 ? 119.218 69.057  134.915 1.00 73.15  ? 111 LEU A CA  1 
ATOM 1422 C C   . LEU B 2 110 ? 119.071 70.568  134.890 1.00 75.87  ? 111 LEU A C   1 
ATOM 1423 O O   . LEU B 2 110 ? 118.873 71.191  135.936 1.00 84.76  ? 111 LEU A O   1 
ATOM 1424 C CB  . LEU B 2 110 ? 117.906 68.387  135.331 1.00 74.63  ? 111 LEU A CB  1 
ATOM 1425 C CG  . LEU B 2 110 ? 116.650 68.812  134.574 1.00 70.82  ? 111 LEU A CG  1 
ATOM 1426 C CD1 . LEU B 2 110 ? 116.812 68.545  133.093 1.00 78.95  ? 111 LEU A CD1 1 
ATOM 1427 C CD2 . LEU B 2 110 ? 115.437 68.084  135.117 1.00 78.92  ? 111 LEU A CD2 1 
ATOM 1428 N N   . THR B 2 111 ? 119.206 71.179  133.730 1.00 74.90  ? 112 THR A N   1 
ATOM 1429 C CA  . THR B 2 111 ? 119.060 72.629  133.585 1.00 81.27  ? 112 THR A CA  1 
ATOM 1430 C C   . THR B 2 111 ? 117.899 72.897  132.674 1.00 81.57  ? 112 THR A C   1 
ATOM 1431 O O   . THR B 2 111 ? 117.722 72.140  131.765 1.00 92.59  ? 112 THR A O   1 
ATOM 1432 C CB  . THR B 2 111 ? 120.370 73.221  133.096 1.00 84.78  ? 112 THR A CB  1 
ATOM 1433 O OG1 . THR B 2 111 ? 120.696 72.614  131.856 1.00 95.95  ? 112 THR A OG1 1 
ATOM 1434 C CG2 . THR B 2 111 ? 121.496 72.958  134.075 1.00 79.11  ? 112 THR A CG2 1 
ATOM 1435 N N   . LEU B 2 112 ? 117.052 73.857  132.984 1.00 64.67  ? 113 LEU A N   1 
ATOM 1436 C CA  . LEU B 2 112 ? 115.857 74.203  132.198 1.00 58.45  ? 113 LEU A CA  1 
ATOM 1437 C C   . LEU B 2 112 ? 115.754 75.724  132.171 1.00 69.97  ? 113 LEU A C   1 
ATOM 1438 O O   . LEU B 2 112 ? 114.662 76.203  131.920 1.00 80.19  ? 113 LEU A O   1 
ATOM 1439 C CB  . LEU B 2 112 ? 114.681 73.507  132.864 1.00 58.84  ? 113 LEU A CB  1 
ATOM 1440 C CG  . LEU B 2 112 ? 114.722 71.983  132.942 1.00 60.95  ? 113 LEU A CG  1 
ATOM 1441 C CD1 . LEU B 2 112 ? 113.655 71.513  133.892 1.00 69.38  ? 113 LEU A CD1 1 
ATOM 1442 C CD2 . LEU B 2 112 ? 114.530 71.384  131.582 1.00 65.40  ? 113 LEU A CD2 1 
ATOM 1443 N N   . GLN B 2 113 ? 116.887 76.416  132.302 1.00 71.88  ? 114 GLN A N   1 
ATOM 1444 C CA  . GLN B 2 113 ? 116.898 77.889  132.435 1.00 72.50  ? 114 GLN A CA  1 
ATOM 1445 C C   . GLN B 2 113 ? 116.462 78.491  131.098 1.00 78.47  ? 114 GLN A C   1 
ATOM 1446 O O   . GLN B 2 113 ? 116.490 77.739  130.110 1.00 90.54  ? 114 GLN A O   1 
ATOM 1447 C CB  . GLN B 2 113 ? 118.331 78.373  132.645 1.00 71.78  ? 114 GLN A CB  1 
ATOM 1448 C CG  . GLN B 2 113 ? 119.235 78.223  131.427 1.00 76.50  ? 114 GLN A CG  1 
ATOM 1449 C CD  . GLN B 2 113 ? 120.649 77.831  131.791 1.00 93.00  ? 114 GLN A CD  1 
ATOM 1450 O OE1 . GLN B 2 113 ? 121.522 78.678  132.006 1.00 94.82  ? 114 GLN A OE1 1 
ATOM 1451 N NE2 . GLN B 2 113 ? 120.881 76.530  131.869 1.00 93.55  ? 114 GLN A NE2 1 
ATOM 1452 N N   . ASN B 2 114 ? 116.057 79.769  131.087 1.00 94.98  ? 115 ASN A N   1 
ATOM 1453 C CA  . ASN B 2 114 ? 115.689 80.532  129.846 1.00 90.67  ? 115 ASN A CA  1 
ATOM 1454 C C   . ASN B 2 114 ? 114.338 80.120  129.052 1.00 87.53  ? 115 ASN A C   1 
ATOM 1455 O O   . ASN B 2 114 ? 113.782 80.809  128.170 1.00 91.80  ? 115 ASN A O   1 
ATOM 1456 C CB  . ASN B 2 114 ? 116.998 80.903  129.137 1.00 85.23  ? 115 ASN A CB  1 
ATOM 1457 C CG  . ASN B 2 114 ? 116.869 81.813  127.943 1.00 97.24  ? 115 ASN A CG  1 
ATOM 1458 O OD1 . ASN B 2 114 ? 115.793 81.927  127.359 1.00 100.77 ? 115 ASN A OD1 1 
ATOM 1459 N ND2 . ASN B 2 114 ? 117.967 82.439  127.543 1.00 106.27 ? 115 ASN A ND2 1 
ATOM 1460 N N   . ASN B 2 115 ? 113.815 78.974  129.502 1.00 81.20  ? 116 ASN A N   1 
ATOM 1461 C CA  . ASN B 2 115 ? 112.584 78.423  128.954 1.00 78.71  ? 116 ASN A CA  1 
ATOM 1462 C C   . ASN B 2 115 ? 111.286 79.183  129.219 1.00 91.23  ? 116 ASN A C   1 
ATOM 1463 O O   . ASN B 2 115 ? 111.279 80.249  129.839 1.00 97.33  ? 116 ASN A O   1 
ATOM 1464 C CB  . ASN B 2 115 ? 112.454 76.930  129.233 1.00 80.86  ? 116 ASN A CB  1 
ATOM 1465 C CG  . ASN B 2 115 ? 113.464 76.109  128.466 1.00 89.60  ? 116 ASN A CG  1 
ATOM 1466 O OD1 . ASN B 2 115 ? 113.378 74.884  128.419 1.00 97.55  ? 116 ASN A OD1 1 
ATOM 1467 N ND2 . ASN B 2 115 ? 114.429 76.782  127.853 1.00 93.62  ? 116 ASN A ND2 1 
ATOM 1468 N N   . GLN B 2 116 ? 110.164 78.648  128.744 1.00 94.79  ? 117 GLN A N   1 
ATOM 1469 C CA  . GLN B 2 116 ? 108.868 79.289  128.927 1.00 93.46  ? 117 GLN A CA  1 
ATOM 1470 C C   . GLN B 2 116 ? 107.933 78.443  129.783 1.00 96.38  ? 117 GLN A C   1 
ATOM 1471 O O   . GLN B 2 116 ? 106.721 78.431  129.563 1.00 103.07 ? 117 GLN A O   1 
ATOM 1472 C CB  . GLN B 2 116 ? 108.223 79.601  127.578 1.00 98.18  ? 117 GLN A CB  1 
ATOM 1473 C CG  . GLN B 2 116 ? 108.850 80.778  126.857 1.00 100.31 ? 117 GLN A CG  1 
ATOM 1474 C CD  . GLN B 2 116 ? 108.895 82.026  127.713 1.00 99.05  ? 117 GLN A CD  1 
ATOM 1475 O OE1 . GLN B 2 116 ? 109.916 82.337  128.325 1.00 97.90  ? 117 GLN A OE1 1 
ATOM 1476 N NE2 . GLN B 2 116 ? 107.784 82.751  127.759 1.00 98.68  ? 117 GLN A NE2 1 
ATOM 1477 N N   . LEU B 2 117 ? 108.479 77.729  130.761 1.00 93.07  ? 118 LEU A N   1 
ATOM 1478 C CA  . LEU B 2 117 ? 107.642 77.017  131.716 1.00 87.02  ? 118 LEU A CA  1 
ATOM 1479 C C   . LEU B 2 117 ? 106.921 78.026  132.597 1.00 93.87  ? 118 LEU A C   1 
ATOM 1480 O O   . LEU B 2 117 ? 107.560 78.837  133.275 1.00 99.50  ? 118 LEU A O   1 
ATOM 1481 C CB  . LEU B 2 117 ? 108.486 76.069  132.563 1.00 91.72  ? 118 LEU A CB  1 
ATOM 1482 C CG  . LEU B 2 117 ? 109.278 75.003  131.809 1.00 95.38  ? 118 LEU A CG  1 
ATOM 1483 C CD1 . LEU B 2 117 ? 110.541 74.648  132.565 1.00 85.60  ? 118 LEU A CD1 1 
ATOM 1484 C CD2 . LEU B 2 117 ? 108.427 73.772  131.582 1.00 103.29 ? 118 LEU A CD2 1 
ATOM 1485 N N   . LYS B 2 118 ? 105.588 77.974  132.618 1.00 98.06  ? 119 LYS A N   1 
ATOM 1486 C CA  . LYS B 2 118 ? 104.792 78.988  133.355 1.00 107.00 ? 119 LYS A CA  1 
ATOM 1487 C C   . LYS B 2 118 ? 104.653 78.582  134.829 1.00 107.70 ? 119 LYS A C   1 
ATOM 1488 O O   . LYS B 2 118 ? 104.188 79.432  135.606 1.00 107.30 ? 119 LYS A O   1 
ATOM 1489 C CB  . LYS B 2 118 ? 103.454 79.148  132.628 1.00 106.78 ? 119 LYS A CB  1 
ATOM 1490 C CG  . LYS B 2 118 ? 103.571 79.377  131.123 1.00 103.64 ? 119 LYS A CG  1 
ATOM 1491 C CD  . LYS B 2 118 ? 104.577 80.448  130.714 1.00 98.55  ? 119 LYS A CD  1 
ATOM 1492 C CE  . LYS B 2 118 ? 104.602 80.757  129.246 1.00 100.36 ? 119 LYS A CE  1 
ATOM 1493 N NZ  . LYS B 2 118 ? 104.416 79.589  128.379 1.00 101.01 ? 119 LYS A NZ  1 
ATOM 1494 N N   . THR B 2 119 ? 104.991 77.343  135.197 1.00 104.70 ? 120 THR A N   1 
ATOM 1495 C CA  . THR B 2 119 ? 104.955 76.874  136.595 1.00 100.32 ? 120 THR A CA  1 
ATOM 1496 C C   . THR B 2 119 ? 106.016 75.820  136.774 1.00 100.96 ? 120 THR A C   1 
ATOM 1497 O O   . THR B 2 119 ? 106.320 75.129  135.779 1.00 116.06 ? 120 THR A O   1 
ATOM 1498 C CB  . THR B 2 119 ? 103.555 76.330  136.885 1.00 102.91 ? 120 THR A CB  1 
ATOM 1499 O OG1 . THR B 2 119 ? 103.670 75.514  138.043 1.00 94.91  ? 120 THR A OG1 1 
ATOM 1500 C CG2 . THR B 2 119 ? 102.986 75.478  135.762 1.00 103.97 ? 120 THR A CG2 1 
ATOM 1501 N N   . VAL B 2 120 ? 106.573 75.671  137.978 1.00 81.02  ? 121 VAL A N   1 
ATOM 1502 C CA  . VAL B 2 120 ? 107.524 74.586  138.235 1.00 77.64  ? 121 VAL A CA  1 
ATOM 1503 C C   . VAL B 2 120 ? 106.881 73.265  137.835 1.00 82.20  ? 121 VAL A C   1 
ATOM 1504 O O   . VAL B 2 120 ? 105.728 72.996  138.225 1.00 89.46  ? 121 VAL A O   1 
ATOM 1505 C CB  . VAL B 2 120 ? 107.935 74.570  139.717 1.00 67.63  ? 121 VAL A CB  1 
ATOM 1506 C CG1 . VAL B 2 120 ? 108.372 73.178  140.135 1.00 69.89  ? 121 VAL A CG1 1 
ATOM 1507 C CG2 . VAL B 2 120 ? 109.041 75.573  139.971 1.00 73.37  ? 121 VAL A CG2 1 
ATOM 1508 N N   . PRO B 2 121 ? 107.550 72.414  137.058 1.00 79.12  ? 122 PRO A N   1 
ATOM 1509 C CA  . PRO B 2 121 ? 106.932 71.137  136.679 1.00 85.30  ? 122 PRO A CA  1 
ATOM 1510 C C   . PRO B 2 121 ? 106.934 70.186  137.862 1.00 87.17  ? 122 PRO A C   1 
ATOM 1511 O O   . PRO B 2 121 ? 107.977 69.638  138.229 1.00 94.03  ? 122 PRO A O   1 
ATOM 1512 C CB  . PRO B 2 121 ? 107.884 70.584  135.610 1.00 74.79  ? 122 PRO A CB  1 
ATOM 1513 C CG  . PRO B 2 121 ? 108.705 71.756  135.169 1.00 68.10  ? 122 PRO A CG  1 
ATOM 1514 C CD  . PRO B 2 121 ? 108.830 72.632  136.370 1.00 71.14  ? 122 PRO A CD  1 
ATOM 1515 N N   . SER B 2 122 ? 105.763 69.978  138.464 1.00 105.53 ? 123 SER A N   1 
ATOM 1516 C CA  . SER B 2 122 ? 105.680 69.157  139.664 1.00 103.42 ? 123 SER A CA  1 
ATOM 1517 C C   . SER B 2 122 ? 105.568 67.669  139.341 1.00 103.79 ? 123 SER A C   1 
ATOM 1518 O O   . SER B 2 122 ? 106.364 66.853  139.815 1.00 104.47 ? 123 SER A O   1 
ATOM 1519 C CB  . SER B 2 122 ? 104.453 69.544  140.493 1.00 110.84 ? 123 SER A CB  1 
ATOM 1520 O OG  . SER B 2 122 ? 104.326 68.711  141.632 1.00 110.45 ? 123 SER A OG  1 
ATOM 1521 N N   . GLU B 2 123 ? 104.597 67.307  138.509 1.00 115.46 ? 124 GLU A N   1 
ATOM 1522 C CA  . GLU B 2 123 ? 104.409 65.906  138.139 1.00 116.52 ? 124 GLU A CA  1 
ATOM 1523 C C   . GLU B 2 123 ? 105.217 65.544  136.899 1.00 119.13 ? 124 GLU A C   1 
ATOM 1524 O O   . GLU B 2 123 ? 104.780 64.780  136.044 1.00 119.39 ? 124 GLU A O   1 
ATOM 1525 C CB  . GLU B 2 123 ? 102.949 65.504  137.977 1.00 115.68 ? 124 GLU A CB  1 
ATOM 1526 C CG  . GLU B 2 123 ? 102.138 65.578  139.256 1.00 121.63 ? 124 GLU A CG  1 
ATOM 1527 C CD  . GLU B 2 123 ? 102.710 64.711  140.360 1.00 126.26 ? 124 GLU A CD  1 
ATOM 1528 O OE1 . GLU B 2 123 ? 103.158 63.584  140.060 1.00 127.13 ? 124 GLU A OE1 1 
ATOM 1529 O OE2 . GLU B 2 123 ? 102.709 65.156  141.526 1.00 125.83 ? 124 GLU A OE2 1 
ATOM 1530 N N   . ALA B 2 124 ? 106.420 66.099  136.804 1.00 109.34 ? 125 ALA A N   1 
ATOM 1531 C CA  . ALA B 2 124 ? 107.372 65.719  135.765 1.00 109.55 ? 125 ALA A CA  1 
ATOM 1532 C C   . ALA B 2 124 ? 108.778 65.408  136.253 1.00 110.87 ? 125 ALA A C   1 
ATOM 1533 O O   . ALA B 2 124 ? 109.484 64.643  135.588 1.00 111.13 ? 125 ALA A O   1 
ATOM 1534 C CB  . ALA B 2 124 ? 107.444 66.840  134.721 1.00 107.27 ? 125 ALA A CB  1 
ATOM 1535 N N   . ILE B 2 125 ? 109.211 65.965  137.379 1.00 93.59  ? 126 ILE A N   1 
ATOM 1536 C CA  . ILE B 2 125 ? 110.498 65.663  137.980 1.00 89.38  ? 126 ILE A CA  1 
ATOM 1537 C C   . ILE B 2 125 ? 110.330 64.763  139.201 1.00 96.28  ? 126 ILE A C   1 
ATOM 1538 O O   . ILE B 2 125 ? 111.247 64.631  140.008 1.00 110.89 ? 126 ILE A O   1 
ATOM 1539 C CB  . ILE B 2 125 ? 111.256 66.952  138.332 1.00 87.32  ? 126 ILE A CB  1 
ATOM 1540 C CG1 . ILE B 2 125 ? 110.495 67.736  139.402 1.00 85.00  ? 126 ILE A CG1 1 
ATOM 1541 C CG2 . ILE B 2 125 ? 111.450 67.806  137.095 1.00 88.80  ? 126 ILE A CG2 1 
ATOM 1542 C CD1 . ILE B 2 125 ? 111.150 69.044  139.782 1.00 87.93  ? 126 ILE A CD1 1 
ATOM 1543 N N   . ARG B 2 126 ? 109.156 64.146  139.344 1.00 106.10 ? 127 ARG A N   1 
ATOM 1544 C CA  . ARG B 2 126 ? 108.861 63.355  140.533 1.00 111.16 ? 127 ARG A CA  1 
ATOM 1545 C C   . ARG B 2 126 ? 109.767 62.134  140.639 1.00 111.93 ? 127 ARG A C   1 
ATOM 1546 O O   . ARG B 2 126 ? 110.268 61.819  141.724 1.00 110.52 ? 127 ARG A O   1 
ATOM 1547 C CB  . ARG B 2 126 ? 107.392 62.934  140.516 1.00 108.37 ? 127 ARG A CB  1 
ATOM 1548 C CG  . ARG B 2 126 ? 106.924 62.231  141.772 1.00 109.49 ? 127 ARG A CG  1 
ATOM 1549 C CD  . ARG B 2 126 ? 105.408 62.145  141.808 1.00 106.95 ? 127 ARG A CD  1 
ATOM 1550 N NE  . ARG B 2 126 ? 104.930 61.409  142.971 1.00 109.21 ? 127 ARG A NE  1 
ATOM 1551 C CZ  . ARG B 2 126 ? 104.839 61.915  144.193 1.00 113.44 ? 127 ARG A CZ  1 
ATOM 1552 N NH1 . ARG B 2 126 ? 105.177 63.168  144.448 1.00 114.64 ? 127 ARG A NH1 1 
ATOM 1553 N NH2 . ARG B 2 126 ? 104.392 61.147  145.182 1.00 112.40 ? 127 ARG A NH2 1 
ATOM 1554 N N   . GLY B 2 127 ? 109.993 61.438  139.526 1.00 104.71 ? 128 GLY A N   1 
ATOM 1555 C CA  . GLY B 2 127 ? 110.744 60.197  139.559 1.00 104.93 ? 128 GLY A CA  1 
ATOM 1556 C C   . GLY B 2 127 ? 112.249 60.338  139.582 1.00 109.03 ? 128 GLY A C   1 
ATOM 1557 O O   . GLY B 2 127 ? 112.945 59.336  139.769 1.00 113.37 ? 128 GLY A O   1 
ATOM 1558 N N   . LEU B 2 128 ? 112.769 61.559  139.391 1.00 112.71 ? 129 LEU A N   1 
ATOM 1559 C CA  . LEU B 2 128 ? 114.229 61.820  139.333 1.00 115.08 ? 129 LEU A CA  1 
ATOM 1560 C C   . LEU B 2 128 ? 114.758 61.785  140.763 1.00 112.42 ? 129 LEU A C   1 
ATOM 1561 O O   . LEU B 2 128 ? 115.018 62.856  141.305 1.00 107.06 ? 129 LEU A O   1 
ATOM 1562 C CB  . LEU B 2 128 ? 114.479 63.157  138.649 1.00 110.49 ? 129 LEU A CB  1 
ATOM 1563 C CG  . LEU B 2 128 ? 113.909 63.322  137.240 1.00 114.07 ? 129 LEU A CG  1 
ATOM 1564 C CD1 . LEU B 2 128 ? 113.857 64.796  136.908 1.00 113.80 ? 129 LEU A CD1 1 
ATOM 1565 C CD2 . LEU B 2 128 ? 114.722 62.567  136.213 1.00 111.75 ? 129 LEU A CD2 1 
ATOM 1566 N N   . SER B 2 129 ? 114.962 60.601  141.331 1.00 119.35 ? 130 SER A N   1 
ATOM 1567 C CA  . SER B 2 129 ? 115.345 60.438  142.726 1.00 118.66 ? 130 SER A CA  1 
ATOM 1568 C C   . SER B 2 129 ? 116.845 60.558  142.961 1.00 118.14 ? 130 SER A C   1 
ATOM 1569 O O   . SER B 2 129 ? 117.293 60.351  144.093 1.00 120.00 ? 130 SER A O   1 
ATOM 1570 C CB  . SER B 2 129 ? 114.856 59.083  143.247 1.00 117.93 ? 130 SER A CB  1 
ATOM 1571 O OG  . SER B 2 129 ? 115.816 58.071  143.003 1.00 113.48 ? 130 SER A OG  1 
ATOM 1572 N N   . ALA B 2 130 ? 117.635 60.881  141.933 1.00 103.13 ? 131 ALA A N   1 
ATOM 1573 C CA  . ALA B 2 130 ? 119.080 60.929  142.122 1.00 101.85 ? 131 ALA A CA  1 
ATOM 1574 C C   . ALA B 2 130 ? 119.650 62.185  141.469 1.00 103.03 ? 131 ALA A C   1 
ATOM 1575 O O   . ALA B 2 130 ? 120.837 62.202  141.126 1.00 107.92 ? 131 ALA A O   1 
ATOM 1576 C CB  . ALA B 2 130 ? 119.731 59.635  141.627 1.00 100.03 ? 131 ALA A CB  1 
ATOM 1577 N N   . LEU B 2 131 ? 118.828 63.236  141.371 1.00 87.79  ? 132 LEU A N   1 
ATOM 1578 C CA  . LEU B 2 131 ? 119.266 64.532  140.800 1.00 93.63  ? 132 LEU A CA  1 
ATOM 1579 C C   . LEU B 2 131 ? 119.999 65.371  141.828 1.00 93.93  ? 132 LEU A C   1 
ATOM 1580 O O   . LEU B 2 131 ? 119.595 65.273  142.983 1.00 95.55  ? 132 LEU A O   1 
ATOM 1581 C CB  . LEU B 2 131 ? 118.022 65.252  140.289 1.00 91.88  ? 132 LEU A CB  1 
ATOM 1582 C CG  . LEU B 2 131 ? 118.188 66.512  139.440 1.00 91.05  ? 132 LEU A CG  1 
ATOM 1583 C CD1 . LEU B 2 131 ? 117.101 66.651  138.409 1.00 89.71  ? 132 LEU A CD1 1 
ATOM 1584 C CD2 . LEU B 2 131 ? 118.171 67.692  140.380 1.00 91.84  ? 132 LEU A CD2 1 
ATOM 1585 N N   . GLN B 2 132 ? 121.035 66.114  141.443 1.00 86.03  ? 133 GLN A N   1 
ATOM 1586 C CA  . GLN B 2 132 ? 121.812 66.898  142.396 1.00 79.88  ? 133 GLN A CA  1 
ATOM 1587 C C   . GLN B 2 132 ? 121.617 68.390  142.191 1.00 83.16  ? 133 GLN A C   1 
ATOM 1588 O O   . GLN B 2 132 ? 121.503 69.128  143.171 1.00 94.54  ? 133 GLN A O   1 
ATOM 1589 C CB  . GLN B 2 132 ? 123.312 66.586  142.427 1.00 88.46  ? 133 GLN A CB  1 
ATOM 1590 C CG  . GLN B 2 132 ? 123.676 65.412  143.318 1.00 94.22  ? 133 GLN A CG  1 
ATOM 1591 C CD  . GLN B 2 132 ? 124.931 64.702  142.858 1.00 93.52  ? 133 GLN A CD  1 
ATOM 1592 O OE1 . GLN B 2 132 ? 125.006 63.474  142.883 1.00 91.58  ? 133 GLN A OE1 1 
ATOM 1593 N NE2 . GLN B 2 132 ? 125.924 65.473  142.433 1.00 91.16  ? 133 GLN A NE2 1 
ATOM 1594 N N   . SER B 2 133 ? 121.577 68.861  140.949 1.00 65.31  ? 134 SER A N   1 
ATOM 1595 C CA  . SER B 2 133 ? 121.415 70.279  140.666 1.00 73.35  ? 134 SER A CA  1 
ATOM 1596 C C   . SER B 2 133 ? 120.277 70.475  139.677 1.00 78.32  ? 134 SER A C   1 
ATOM 1597 O O   . SER B 2 133 ? 120.123 69.696  138.733 1.00 88.41  ? 134 SER A O   1 
ATOM 1598 C CB  . SER B 2 133 ? 122.705 70.888  140.111 1.00 78.68  ? 134 SER A CB  1 
ATOM 1599 O OG  . SER B 2 133 ? 122.859 70.584  138.738 1.00 87.17  ? 134 SER A OG  1 
ATOM 1600 N N   . LEU B 2 134 ? 119.387 71.451  139.922 1.00 67.09  ? 135 LEU A N   1 
ATOM 1601 C CA  . LEU B 2 134 ? 118.215 71.750  139.053 1.00 57.15  ? 135 LEU A CA  1 
ATOM 1602 C C   . LEU B 2 134 ? 118.215 73.252  138.841 1.00 60.27  ? 135 LEU A C   1 
ATOM 1603 O O   . LEU B 2 134 ? 118.158 73.935  139.821 1.00 67.03  ? 135 LEU A O   1 
ATOM 1604 C CB  . LEU B 2 134 ? 116.871 71.401  139.666 1.00 58.21  ? 135 LEU A CB  1 
ATOM 1605 C CG  . LEU B 2 134 ? 115.637 71.626  138.797 1.00 59.02  ? 135 LEU A CG  1 
ATOM 1606 C CD1 . LEU B 2 134 ? 115.611 70.618  137.678 1.00 67.28  ? 135 LEU A CD1 1 
ATOM 1607 C CD2 . LEU B 2 134 ? 114.406 71.519  139.653 1.00 64.24  ? 135 LEU A CD2 1 
ATOM 1608 N N   . ARG B 2 135 ? 118.221 73.659  137.575 1.00 67.15  ? 136 ARG A N   1 
ATOM 1609 C CA  . ARG B 2 135 ? 118.133 75.077  137.196 1.00 70.02  ? 136 ARG A CA  1 
ATOM 1610 C C   . ARG B 2 135 ? 116.726 75.313  136.675 1.00 76.35  ? 136 ARG A C   1 
ATOM 1611 O O   . ARG B 2 135 ? 116.292 74.494  135.855 1.00 86.84  ? 136 ARG A O   1 
ATOM 1612 C CB  . ARG B 2 135 ? 119.124 75.331  136.065 1.00 72.90  ? 136 ARG A CB  1 
ATOM 1613 C CG  . ARG B 2 135 ? 120.257 76.277  136.412 1.00 72.69  ? 136 ARG A CG  1 
ATOM 1614 C CD  . ARG B 2 135 ? 120.690 77.006  135.202 1.00 80.97  ? 136 ARG A CD  1 
ATOM 1615 N NE  . ARG B 2 135 ? 122.069 76.661  134.851 1.00 78.43  ? 136 ARG A NE  1 
ATOM 1616 C CZ  . ARG B 2 135 ? 123.110 77.390  135.209 1.00 80.50  ? 136 ARG A CZ  1 
ATOM 1617 N NH1 . ARG B 2 135 ? 123.900 77.925  134.296 1.00 81.56  ? 136 ARG A NH1 1 
ATOM 1618 N NH2 . ARG B 2 135 ? 123.345 77.588  136.491 1.00 73.99  ? 136 ARG A NH2 1 
ATOM 1619 N N   . LEU B 2 136 ? 115.983 76.262  137.225 1.00 54.39  ? 137 LEU A N   1 
ATOM 1620 C CA  . LEU B 2 136 ? 114.695 76.668  136.674 1.00 44.84  ? 137 LEU A CA  1 
ATOM 1621 C C   . LEU B 2 136 ? 114.643 78.184  136.553 1.00 58.93  ? 137 LEU A C   1 
ATOM 1622 O O   . LEU B 2 136 ? 113.559 78.758  136.421 1.00 67.67  ? 137 LEU A O   1 
ATOM 1623 C CB  . LEU B 2 136 ? 113.581 76.171  137.595 1.00 43.33  ? 137 LEU A CB  1 
ATOM 1624 C CG  . LEU B 2 136 ? 113.436 74.657  137.708 1.00 49.62  ? 137 LEU A CG  1 
ATOM 1625 C CD1 . LEU B 2 136 ? 112.425 74.301  138.779 1.00 61.83  ? 137 LEU A CD1 1 
ATOM 1626 C CD2 . LEU B 2 136 ? 113.034 74.066  136.373 1.00 53.34  ? 137 LEU A CD2 1 
ATOM 1627 N N   . ASP B 2 137 ? 115.796 78.842  136.592 1.00 67.29  ? 138 ASP A N   1 
ATOM 1628 C CA  . ASP B 2 137 ? 115.850 80.292  136.608 1.00 67.28  ? 138 ASP A CA  1 
ATOM 1629 C C   . ASP B 2 137 ? 115.498 80.872  135.242 1.00 69.34  ? 138 ASP A C   1 
ATOM 1630 O O   . ASP B 2 137 ? 115.421 80.168  134.233 1.00 85.16  ? 138 ASP A O   1 
ATOM 1631 C CB  . ASP B 2 137 ? 117.231 80.770  137.040 1.00 72.78  ? 138 ASP A CB  1 
ATOM 1632 C CG  . ASP B 2 137 ? 118.325 80.305  136.111 1.00 88.28  ? 138 ASP A CG  1 
ATOM 1633 O OD1 . ASP B 2 137 ? 118.318 79.115  135.739 1.00 98.83  ? 138 ASP A OD1 1 
ATOM 1634 O OD2 . ASP B 2 137 ? 119.196 81.127  135.757 1.00 87.54  ? 138 ASP A OD2 1 
ATOM 1635 N N   . ALA B 2 138 ? 115.264 82.181  135.233 1.00 77.18  ? 139 ALA A N   1 
ATOM 1636 C CA  . ALA B 2 138 ? 114.955 82.973  134.046 1.00 78.57  ? 139 ALA A CA  1 
ATOM 1637 C C   . ALA B 2 138 ? 113.687 82.519  133.337 1.00 79.35  ? 139 ALA A C   1 
ATOM 1638 O O   . ALA B 2 138 ? 113.403 82.989  132.230 1.00 85.58  ? 139 ALA A O   1 
ATOM 1639 C CB  . ALA B 2 138 ? 116.128 82.987  133.060 1.00 88.41  ? 139 ALA A CB  1 
ATOM 1640 N N   . ASN B 2 139 ? 112.919 81.618  133.934 1.00 74.43  ? 140 ASN A N   1 
ATOM 1641 C CA  . ASN B 2 139 ? 111.607 81.278  133.415 1.00 76.34  ? 140 ASN A CA  1 
ATOM 1642 C C   . ASN B 2 139 ? 110.575 82.275  133.925 1.00 89.15  ? 140 ASN A C   1 
ATOM 1643 O O   . ASN B 2 139 ? 110.824 83.042  134.857 1.00 102.71 ? 140 ASN A O   1 
ATOM 1644 C CB  . ASN B 2 139 ? 111.209 79.861  133.824 1.00 74.01  ? 140 ASN A CB  1 
ATOM 1645 C CG  . ASN B 2 139 ? 111.949 78.803  133.042 1.00 80.33  ? 140 ASN A CG  1 
ATOM 1646 O OD1 . ASN B 2 139 ? 112.671 79.108  132.096 1.00 87.84  ? 140 ASN A OD1 1 
ATOM 1647 N ND2 . ASN B 2 139 ? 111.773 77.549  133.432 1.00 78.53  ? 140 ASN A ND2 1 
ATOM 1648 N N   . HIS B 2 140 ? 109.403 82.259  133.298 1.00 84.00  ? 141 HIS A N   1 
ATOM 1649 C CA  . HIS B 2 140 ? 108.284 83.076  133.760 1.00 84.24  ? 141 HIS A CA  1 
ATOM 1650 C C   . HIS B 2 140 ? 107.369 82.242  134.656 1.00 86.41  ? 141 HIS A C   1 
ATOM 1651 O O   . HIS B 2 140 ? 106.217 81.950  134.339 1.00 92.98  ? 141 HIS A O   1 
ATOM 1652 C CB  . HIS B 2 140 ? 107.535 83.666  132.573 1.00 89.47  ? 141 HIS A CB  1 
ATOM 1653 C CG  . HIS B 2 140 ? 108.402 84.471  131.659 1.00 92.93  ? 141 HIS A CG  1 
ATOM 1654 N ND1 . HIS B 2 140 ? 108.693 84.078  130.370 1.00 93.47  ? 141 HIS A ND1 1 
ATOM 1655 C CD2 . HIS B 2 140 ? 109.053 85.642  131.851 1.00 88.15  ? 141 HIS A CD2 1 
ATOM 1656 C CE1 . HIS B 2 140 ? 109.480 84.976  129.806 1.00 93.94  ? 141 HIS A CE1 1 
ATOM 1657 N NE2 . HIS B 2 140 ? 109.714 85.935  130.683 1.00 93.55  ? 141 HIS A NE2 1 
ATOM 1658 N N   . ILE B 2 141 ? 107.922 81.853  135.798 1.00 87.14  ? 142 ILE A N   1 
ATOM 1659 C CA  . ILE B 2 141 ? 107.219 81.011  136.757 1.00 88.18  ? 142 ILE A CA  1 
ATOM 1660 C C   . ILE B 2 141 ? 106.458 81.909  137.720 1.00 98.10  ? 142 ILE A C   1 
ATOM 1661 O O   . ILE B 2 141 ? 107.048 82.774  138.377 1.00 100.14 ? 142 ILE A O   1 
ATOM 1662 C CB  . ILE B 2 141 ? 108.191 80.090  137.506 1.00 84.10  ? 142 ILE A CB  1 
ATOM 1663 C CG1 . ILE B 2 141 ? 108.685 78.983  136.576 1.00 85.30  ? 142 ILE A CG1 1 
ATOM 1664 C CG2 . ILE B 2 141 ? 107.517 79.486  138.721 1.00 89.61  ? 142 ILE A CG2 1 
ATOM 1665 C CD1 . ILE B 2 141 ? 109.484 77.916  137.272 1.00 85.97  ? 142 ILE A CD1 1 
ATOM 1666 N N   . THR B 2 142 ? 105.145 81.706  137.803 1.00 103.31 ? 143 THR A N   1 
ATOM 1667 C CA  . THR B 2 142 ? 104.282 82.503  138.664 1.00 99.33  ? 143 THR A CA  1 
ATOM 1668 C C   . THR B 2 142 ? 103.880 81.763  139.932 1.00 97.43  ? 143 THR A C   1 
ATOM 1669 O O   . THR B 2 142 ? 103.888 82.347  141.018 1.00 103.81 ? 143 THR A O   1 
ATOM 1670 C CB  . THR B 2 142 ? 103.026 82.933  137.897 1.00 99.97  ? 143 THR A CB  1 
ATOM 1671 O OG1 . THR B 2 142 ? 102.229 81.780  137.605 1.00 104.30 ? 143 THR A OG1 1 
ATOM 1672 C CG2 . THR B 2 142 ? 103.409 83.616  136.596 1.00 98.37  ? 143 THR A CG2 1 
ATOM 1673 N N   . SER B 2 143 ? 103.529 80.488  139.767 1.00 94.53  ? 144 SER A N   1 
ATOM 1674 C CA  . SER B 2 143 ? 103.061 79.655  140.893 1.00 101.10 ? 144 SER A CA  1 
ATOM 1675 C C   . SER B 2 143 ? 103.949 78.421  141.003 1.00 99.28  ? 144 SER A C   1 
ATOM 1676 O O   . SER B 2 143 ? 104.502 78.020  139.963 1.00 106.06 ? 144 SER A O   1 
ATOM 1677 C CB  . SER B 2 143 ? 101.635 79.254  140.686 1.00 103.53 ? 144 SER A CB  1 
ATOM 1678 O OG  . SER B 2 143 ? 101.421 78.828  139.347 1.00 105.29 ? 144 SER A OG  1 
ATOM 1679 N N   . VAL B 2 144 ? 104.116 77.874  142.213 1.00 88.40  ? 145 VAL A N   1 
ATOM 1680 C CA  . VAL B 2 144 ? 104.898 76.625  142.444 1.00 87.38  ? 145 VAL A CA  1 
ATOM 1681 C C   . VAL B 2 144 ? 103.941 75.642  143.140 1.00 89.94  ? 145 VAL A C   1 
ATOM 1682 O O   . VAL B 2 144 ? 103.638 75.863  144.330 1.00 94.95  ? 145 VAL A O   1 
ATOM 1683 C CB  . VAL B 2 144 ? 106.180 76.840  143.269 1.00 83.89  ? 145 VAL A CB  1 
ATOM 1684 C CG1 . VAL B 2 144 ? 106.859 75.517  143.596 1.00 89.28  ? 145 VAL A CG1 1 
ATOM 1685 C CG2 . VAL B 2 144 ? 107.156 77.754  142.546 1.00 85.04  ? 145 VAL A CG2 1 
ATOM 1686 N N   . PRO B 2 145 ? 103.439 74.588  142.458 1.00 97.05  ? 146 PRO A N   1 
ATOM 1687 C CA  . PRO B 2 145 ? 102.476 73.658  143.057 1.00 98.00  ? 146 PRO A CA  1 
ATOM 1688 C C   . PRO B 2 145 ? 103.038 73.198  144.393 1.00 99.45  ? 146 PRO A C   1 
ATOM 1689 O O   . PRO B 2 145 ? 104.250 73.043  144.565 1.00 107.00 ? 146 PRO A O   1 
ATOM 1690 C CB  . PRO B 2 145 ? 102.419 72.508  142.046 1.00 99.48  ? 146 PRO A CB  1 
ATOM 1691 C CG  . PRO B 2 145 ? 102.829 73.125  140.756 1.00 99.59  ? 146 PRO A CG  1 
ATOM 1692 C CD  . PRO B 2 145 ? 103.840 74.177  141.104 1.00 101.15 ? 146 PRO A CD  1 
ATOM 1693 N N   . GLU B 2 146 ? 102.147 73.020  145.377 1.00 116.23 ? 147 GLU A N   1 
ATOM 1694 C CA  . GLU B 2 146 ? 102.552 72.646  146.753 1.00 118.67 ? 147 GLU A CA  1 
ATOM 1695 C C   . GLU B 2 146 ? 103.182 71.254  146.762 1.00 122.19 ? 147 GLU A C   1 
ATOM 1696 O O   . GLU B 2 146 ? 104.149 71.059  147.530 1.00 124.39 ? 147 GLU A O   1 
ATOM 1697 C CB  . GLU B 2 146 ? 101.310 72.630  147.638 1.00 121.27 ? 147 GLU A CB  1 
ATOM 1698 C CG  . GLU B 2 146 ? 101.622 72.700  149.127 1.00 125.70 ? 147 GLU A CG  1 
ATOM 1699 C CD  . GLU B 2 146 ? 100.401 72.613  150.021 1.00 129.06 ? 147 GLU A CD  1 
ATOM 1700 O OE1 . GLU B 2 146 ? 100.284 73.459  150.931 1.00 129.69 ? 147 GLU A OE1 1 
ATOM 1701 O OE2 . GLU B 2 146 ? 99.570  71.703  149.811 1.00 126.51 ? 147 GLU A OE2 1 
ATOM 1702 N N   . ASP B 2 147 ? 102.680 70.330  145.938 1.00 122.50 ? 148 ASP A N   1 
ATOM 1703 C CA  . ASP B 2 147 ? 103.173 68.960  145.926 1.00 124.31 ? 148 ASP A CA  1 
ATOM 1704 C C   . ASP B 2 147 ? 104.539 68.919  145.256 1.00 122.50 ? 148 ASP A C   1 
ATOM 1705 O O   . ASP B 2 147 ? 105.209 67.882  145.320 1.00 120.77 ? 148 ASP A O   1 
ATOM 1706 C CB  . ASP B 2 147 ? 102.234 67.968  145.237 1.00 130.38 ? 148 ASP A CB  1 
ATOM 1707 C CG  . ASP B 2 147 ? 102.589 66.527  145.536 1.00 134.12 ? 148 ASP A CG  1 
ATOM 1708 O OD1 . ASP B 2 147 ? 103.116 66.259  146.636 1.00 133.72 ? 148 ASP A OD1 1 
ATOM 1709 O OD2 . ASP B 2 147 ? 102.345 65.663  144.669 1.00 134.97 ? 148 ASP A OD2 1 
ATOM 1710 N N   . SER B 2 148 ? 104.970 70.009  144.626 1.00 110.09 ? 149 SER A N   1 
ATOM 1711 C CA  . SER B 2 148 ? 106.201 70.000  143.852 1.00 108.89 ? 149 SER A CA  1 
ATOM 1712 C C   . SER B 2 148 ? 107.410 69.730  144.743 1.00 109.77 ? 149 SER A C   1 
ATOM 1713 O O   . SER B 2 148 ? 107.366 69.884  145.967 1.00 110.66 ? 149 SER A O   1 
ATOM 1714 C CB  . SER B 2 148 ? 106.385 71.328  143.121 1.00 106.59 ? 149 SER A CB  1 
ATOM 1715 O OG  . SER B 2 148 ? 107.089 72.252  143.929 1.00 104.28 ? 149 SER A OG  1 
ATOM 1716 N N   . PHE B 2 149 ? 108.499 69.306  144.101 1.00 106.44 ? 150 PHE A N   1 
ATOM 1717 C CA  . PHE B 2 149 ? 109.777 69.004  144.739 1.00 103.08 ? 150 PHE A CA  1 
ATOM 1718 C C   . PHE B 2 149 ? 109.694 67.823  145.695 1.00 105.78 ? 150 PHE A C   1 
ATOM 1719 O O   . PHE B 2 149 ? 110.558 67.665  146.562 1.00 110.19 ? 150 PHE A O   1 
ATOM 1720 C CB  . PHE B 2 149 ? 110.339 70.229  145.468 1.00 101.19 ? 150 PHE A CB  1 
ATOM 1721 C CG  . PHE B 2 149 ? 110.707 71.354  144.553 1.00 99.38  ? 150 PHE A CG  1 
ATOM 1722 C CD1 . PHE B 2 149 ? 111.058 71.106  143.239 1.00 100.55 ? 150 PHE A CD1 1 
ATOM 1723 C CD2 . PHE B 2 149 ? 110.699 72.661  145.003 1.00 98.56  ? 150 PHE A CD2 1 
ATOM 1724 C CE1 . PHE B 2 149 ? 111.394 72.138  142.392 1.00 101.63 ? 150 PHE A CE1 1 
ATOM 1725 C CE2 . PHE B 2 149 ? 111.036 73.697  144.160 1.00 97.47  ? 150 PHE A CE2 1 
ATOM 1726 C CZ  . PHE B 2 149 ? 111.384 73.435  142.853 1.00 103.28 ? 150 PHE A CZ  1 
ATOM 1727 N N   . GLU B 2 150 ? 108.672 66.986  145.558 1.00 114.08 ? 151 GLU A N   1 
ATOM 1728 C CA  . GLU B 2 150 ? 108.554 65.798  146.387 1.00 113.64 ? 151 GLU A CA  1 
ATOM 1729 C C   . GLU B 2 150 ? 109.344 64.649  145.775 1.00 113.33 ? 151 GLU A C   1 
ATOM 1730 O O   . GLU B 2 150 ? 109.257 64.386  144.573 1.00 113.13 ? 151 GLU A O   1 
ATOM 1731 C CB  . GLU B 2 150 ? 107.087 65.401  146.548 1.00 113.67 ? 151 GLU A CB  1 
ATOM 1732 C CG  . GLU B 2 150 ? 106.811 64.541  147.767 1.00 117.68 ? 151 GLU A CG  1 
ATOM 1733 C CD  . GLU B 2 150 ? 106.910 63.060  147.470 1.00 125.37 ? 151 GLU A CD  1 
ATOM 1734 O OE1 . GLU B 2 150 ? 107.007 62.697  146.279 1.00 125.01 ? 151 GLU A OE1 1 
ATOM 1735 O OE2 . GLU B 2 150 ? 106.892 62.258  148.427 1.00 128.20 ? 151 GLU A OE2 1 
ATOM 1736 N N   . GLY B 2 151 ? 110.119 63.963  146.613 1.00 109.34 ? 152 GLY A N   1 
ATOM 1737 C CA  . GLY B 2 151 ? 110.911 62.836  146.178 1.00 111.18 ? 152 GLY A CA  1 
ATOM 1738 C C   . GLY B 2 151 ? 112.323 63.165  145.744 1.00 114.31 ? 152 GLY A C   1 
ATOM 1739 O O   . GLY B 2 151 ? 113.103 62.240  145.483 1.00 115.21 ? 152 GLY A O   1 
ATOM 1740 N N   . LEU B 2 152 ? 112.681 64.447  145.658 1.00 111.69 ? 153 LEU A N   1 
ATOM 1741 C CA  . LEU B 2 152 ? 114.035 64.851  145.277 1.00 112.48 ? 153 LEU A CA  1 
ATOM 1742 C C   . LEU B 2 152 ? 114.942 64.763  146.505 1.00 115.23 ? 153 LEU A C   1 
ATOM 1743 O O   . LEU B 2 152 ? 115.329 65.760  147.118 1.00 118.12 ? 153 LEU A O   1 
ATOM 1744 C CB  . LEU B 2 152 ? 114.030 66.252  144.683 1.00 108.15 ? 153 LEU A CB  1 
ATOM 1745 C CG  . LEU B 2 152 ? 113.247 66.471  143.387 1.00 105.61 ? 153 LEU A CG  1 
ATOM 1746 C CD1 . LEU B 2 152 ? 113.772 67.687  142.647 1.00 105.81 ? 153 LEU A CD1 1 
ATOM 1747 C CD2 . LEU B 2 152 ? 113.305 65.245  142.500 1.00 110.28 ? 153 LEU A CD2 1 
ATOM 1748 N N   . VAL B 2 153 ? 115.286 63.521  146.860 1.00 107.07 ? 154 VAL A N   1 
ATOM 1749 C CA  . VAL B 2 153 ? 116.056 63.264  148.076 1.00 106.15 ? 154 VAL A CA  1 
ATOM 1750 C C   . VAL B 2 153 ? 117.546 63.495  147.900 1.00 105.25 ? 154 VAL A C   1 
ATOM 1751 O O   . VAL B 2 153 ? 118.308 63.288  148.853 1.00 107.91 ? 154 VAL A O   1 
ATOM 1752 C CB  . VAL B 2 153 ? 115.826 61.822  148.569 1.00 103.49 ? 154 VAL A CB  1 
ATOM 1753 C CG1 . VAL B 2 153 ? 114.338 61.528  148.658 1.00 103.41 ? 154 VAL A CG1 1 
ATOM 1754 C CG2 . VAL B 2 153 ? 116.513 60.833  147.644 1.00 102.11 ? 154 VAL A CG2 1 
ATOM 1755 N N   . GLN B 2 154 ? 117.991 63.919  146.717 1.00 101.07 ? 155 GLN A N   1 
ATOM 1756 C CA  . GLN B 2 154 ? 119.410 64.129  146.465 1.00 101.33 ? 155 GLN A CA  1 
ATOM 1757 C C   . GLN B 2 154 ? 119.718 65.520  145.924 1.00 102.27 ? 155 GLN A C   1 
ATOM 1758 O O   . GLN B 2 154 ? 120.855 65.769  145.509 1.00 106.11 ? 155 GLN A O   1 
ATOM 1759 C CB  . GLN B 2 154 ? 119.945 63.070  145.494 1.00 103.95 ? 155 GLN A CB  1 
ATOM 1760 C CG  . GLN B 2 154 ? 119.990 61.669  146.074 1.00 106.01 ? 155 GLN A CG  1 
ATOM 1761 C CD  . GLN B 2 154 ? 120.859 61.580  147.312 1.00 110.14 ? 155 GLN A CD  1 
ATOM 1762 O OE1 . GLN B 2 154 ? 121.964 62.119  147.348 1.00 111.40 ? 155 GLN A OE1 1 
ATOM 1763 N NE2 . GLN B 2 154 ? 120.361 60.898  148.336 1.00 108.20 ? 155 GLN A NE2 1 
ATOM 1764 N N   . LEU B 2 155 ? 118.745 66.426  145.910 1.00 87.27  ? 156 LEU A N   1 
ATOM 1765 C CA  . LEU B 2 155 ? 118.979 67.761  145.380 1.00 89.95  ? 156 LEU A CA  1 
ATOM 1766 C C   . LEU B 2 155 ? 119.970 68.523  146.250 1.00 91.21  ? 156 LEU A C   1 
ATOM 1767 O O   . LEU B 2 155 ? 119.923 68.455  147.481 1.00 98.06  ? 156 LEU A O   1 
ATOM 1768 C CB  . LEU B 2 155 ? 117.664 68.532  145.281 1.00 90.17  ? 156 LEU A CB  1 
ATOM 1769 C CG  . LEU B 2 155 ? 117.726 69.840  144.493 1.00 93.95  ? 156 LEU A CG  1 
ATOM 1770 C CD1 . LEU B 2 155 ? 118.062 69.566  143.049 1.00 99.04  ? 156 LEU A CD1 1 
ATOM 1771 C CD2 . LEU B 2 155 ? 116.415 70.587  144.587 1.00 97.48  ? 156 LEU A CD2 1 
ATOM 1772 N N   . ARG B 2 156 ? 120.873 69.249  145.601 1.00 85.01  ? 157 ARG A N   1 
ATOM 1773 C CA  . ARG B 2 156 ? 121.894 70.028  146.289 1.00 85.85  ? 157 ARG A CA  1 
ATOM 1774 C C   . ARG B 2 156 ? 121.849 71.507  145.952 1.00 89.17  ? 157 ARG A C   1 
ATOM 1775 O O   . ARG B 2 156 ? 122.085 72.340  146.830 1.00 101.18 ? 157 ARG A O   1 
ATOM 1776 C CB  . ARG B 2 156 ? 123.287 69.479  145.960 1.00 88.70  ? 157 ARG A CB  1 
ATOM 1777 C CG  . ARG B 2 156 ? 123.579 68.127  146.576 1.00 89.88  ? 157 ARG A CG  1 
ATOM 1778 C CD  . ARG B 2 156 ? 125.061 67.964  146.858 1.00 90.57  ? 157 ARG A CD  1 
ATOM 1779 N NE  . ARG B 2 156 ? 125.600 66.761  146.236 1.00 93.82  ? 157 ARG A NE  1 
ATOM 1780 C CZ  . ARG B 2 156 ? 125.468 65.539  146.732 1.00 99.98  ? 157 ARG A CZ  1 
ATOM 1781 N NH1 . ARG B 2 156 ? 124.815 65.318  147.861 1.00 94.62  ? 157 ARG A NH1 1 
ATOM 1782 N NH2 . ARG B 2 156 ? 126.003 64.512  146.078 1.00 99.59  ? 157 ARG A NH2 1 
ATOM 1783 N N   . HIS B 2 157 ? 121.559 71.860  144.704 1.00 76.71  ? 158 HIS A N   1 
ATOM 1784 C CA  . HIS B 2 157 ? 121.491 73.250  144.283 1.00 83.75  ? 158 HIS A CA  1 
ATOM 1785 C C   . HIS B 2 157 ? 120.197 73.485  143.522 1.00 86.93  ? 158 HIS A C   1 
ATOM 1786 O O   . HIS B 2 157 ? 119.761 72.632  142.744 1.00 94.69  ? 158 HIS A O   1 
ATOM 1787 C CB  . HIS B 2 157 ? 122.691 73.624  143.411 1.00 80.94  ? 158 HIS A CB  1 
ATOM 1788 C CG  . HIS B 2 157 ? 123.919 72.822  143.701 1.00 84.23  ? 158 HIS A CG  1 
ATOM 1789 N ND1 . HIS B 2 157 ? 124.208 71.642  143.050 1.00 93.04  ? 158 HIS A ND1 1 
ATOM 1790 C CD2 . HIS B 2 157 ? 124.932 73.026  144.575 1.00 89.91  ? 158 HIS A CD2 1 
ATOM 1791 C CE1 . HIS B 2 157 ? 125.347 71.156  143.509 1.00 93.05  ? 158 HIS A CE1 1 
ATOM 1792 N NE2 . HIS B 2 157 ? 125.807 71.977  144.435 1.00 91.72  ? 158 HIS A NE2 1 
ATOM 1793 N N   . LEU B 2 158 ? 119.585 74.643  143.753 1.00 75.56  ? 159 LEU A N   1 
ATOM 1794 C CA  . LEU B 2 158 ? 118.326 75.004  143.118 1.00 64.25  ? 159 LEU A CA  1 
ATOM 1795 C C   . LEU B 2 158 ? 118.462 76.432  142.616 1.00 71.93  ? 159 LEU A C   1 
ATOM 1796 O O   . LEU B 2 158 ? 118.936 77.307  143.345 1.00 80.83  ? 159 LEU A O   1 
ATOM 1797 C CB  . LEU B 2 158 ? 117.164 74.915  144.109 1.00 67.22  ? 159 LEU A CB  1 
ATOM 1798 C CG  . LEU B 2 158 ? 115.763 74.989  143.507 1.00 69.62  ? 159 LEU A CG  1 
ATOM 1799 C CD1 . LEU B 2 158 ? 115.586 73.901  142.468 1.00 71.10  ? 159 LEU A CD1 1 
ATOM 1800 C CD2 . LEU B 2 158 ? 114.709 74.873  144.590 1.00 74.73  ? 159 LEU A CD2 1 
ATOM 1801 N N   . TRP B 2 159 ? 118.134 76.644  141.340 1.00 67.84  ? 160 TRP A N   1 
ATOM 1802 C CA  . TRP B 2 159 ? 118.102 78.010  140.777 1.00 69.75  ? 160 TRP A CA  1 
ATOM 1803 C C   . TRP B 2 159 ? 116.636 78.353  140.582 1.00 76.38  ? 160 TRP A C   1 
ATOM 1804 O O   . TRP B 2 159 ? 115.896 77.454  140.158 1.00 91.20  ? 160 TRP A O   1 
ATOM 1805 C CB  . TRP B 2 159 ? 118.886 78.114  139.466 1.00 71.98  ? 160 TRP A CB  1 
ATOM 1806 C CG  . TRP B 2 159 ? 120.382 78.062  139.628 1.00 77.97  ? 160 TRP A CG  1 
ATOM 1807 C CD1 . TRP B 2 159 ? 121.233 79.112  139.805 1.00 78.25  ? 160 TRP A CD1 1 
ATOM 1808 C CD2 . TRP B 2 159 ? 121.210 76.881  139.605 1.00 77.40  ? 160 TRP A CD2 1 
ATOM 1809 N NE1 . TRP B 2 159 ? 122.526 78.667  139.896 1.00 78.75  ? 160 TRP A NE1 1 
ATOM 1810 C CE2 . TRP B 2 159 ? 122.542 77.303  139.777 1.00 75.86  ? 160 TRP A CE2 1 
ATOM 1811 C CE3 . TRP B 2 159 ? 120.952 75.518  139.460 1.00 79.51  ? 160 TRP A CE3 1 
ATOM 1812 C CZ2 . TRP B 2 159 ? 123.606 76.404  139.797 1.00 73.21  ? 160 TRP A CZ2 1 
ATOM 1813 C CZ3 . TRP B 2 159 ? 122.001 74.629  139.483 1.00 75.16  ? 160 TRP A CZ3 1 
ATOM 1814 C CH2 . TRP B 2 159 ? 123.310 75.068  139.656 1.00 72.67  ? 160 TRP A CH2 1 
ATOM 1815 N N   . LEU B 2 160 ? 116.184 79.531  141.012 1.00 61.00  ? 161 LEU A N   1 
ATOM 1816 C CA  . LEU B 2 160 ? 114.785 79.965  140.764 1.00 52.22  ? 161 LEU A CA  1 
ATOM 1817 C C   . LEU B 2 160 ? 114.773 81.482  140.536 1.00 63.20  ? 161 LEU A C   1 
ATOM 1818 O O   . LEU B 2 160 ? 113.665 82.053  140.574 1.00 70.98  ? 161 LEU A O   1 
ATOM 1819 C CB  . LEU B 2 160 ? 113.873 79.582  141.932 1.00 48.57  ? 161 LEU A CB  1 
ATOM 1820 C CG  . LEU B 2 160 ? 113.862 78.118  142.385 1.00 52.24  ? 161 LEU A CG  1 
ATOM 1821 C CD1 . LEU B 2 160 ? 113.209 78.023  143.744 1.00 62.15  ? 161 LEU A CD1 1 
ATOM 1822 C CD2 . LEU B 2 160 ? 113.154 77.200  141.404 1.00 60.53  ? 161 LEU A CD2 1 
ATOM 1823 N N   . ASP B 2 161 ? 115.925 82.118  140.279 1.00 74.58  ? 162 ASP A N   1 
ATOM 1824 C CA  . ASP B 2 161 ? 115.976 83.585  140.169 1.00 75.12  ? 162 ASP A CA  1 
ATOM 1825 C C   . ASP B 2 161 ? 115.364 84.107  138.890 1.00 78.55  ? 162 ASP A C   1 
ATOM 1826 O O   . ASP B 2 161 ? 114.989 83.293  138.104 1.00 88.30  ? 162 ASP A O   1 
ATOM 1827 C CB  . ASP B 2 161 ? 117.368 84.139  140.367 1.00 87.53  ? 162 ASP A CB  1 
ATOM 1828 C CG  . ASP B 2 161 ? 118.539 83.514  139.631 1.00 99.31  ? 162 ASP A CG  1 
ATOM 1829 O OD1 . ASP B 2 161 ? 118.427 82.358  139.213 1.00 99.29  ? 162 ASP A OD1 1 
ATOM 1830 O OD2 . ASP B 2 161 ? 119.584 84.185  139.538 1.00 99.06  ? 162 ASP A OD2 1 
ATOM 1831 N N   . ASP B 2 162 ? 115.136 85.418  138.783 1.00 88.12  ? 163 ASP A N   1 
ATOM 1832 C CA  . ASP B 2 162 ? 114.617 86.038  137.533 1.00 86.72  ? 163 ASP A CA  1 
ATOM 1833 C C   . ASP B 2 162 ? 113.287 85.357  137.166 1.00 88.58  ? 163 ASP A C   1 
ATOM 1834 O O   . ASP B 2 162 ? 113.100 85.038  135.976 1.00 92.43  ? 163 ASP A O   1 
ATOM 1835 C CB  . ASP B 2 162 ? 115.709 85.966  136.479 1.00 97.26  ? 163 ASP A CB  1 
ATOM 1836 C CG  . ASP B 2 162 ? 115.419 86.641  135.146 1.00 105.91 ? 163 ASP A CG  1 
ATOM 1837 O OD1 . ASP B 2 162 ? 114.322 87.221  135.015 1.00 108.72 ? 163 ASP A OD1 1 
ATOM 1838 O OD2 . ASP B 2 162 ? 116.295 86.601  134.258 1.00 107.19 ? 163 ASP A OD2 1 
ATOM 1839 N N   . ASN B 2 163 ? 112.414 85.172  138.137 1.00 84.01  ? 164 ASN A N   1 
ATOM 1840 C CA  . ASN B 2 163 ? 111.105 84.522  137.917 1.00 80.53  ? 164 ASN A CA  1 
ATOM 1841 C C   . ASN B 2 163 ? 110.093 85.563  138.380 1.00 92.11  ? 164 ASN A C   1 
ATOM 1842 O O   . ASN B 2 163 ? 110.516 86.715  138.607 1.00 99.33  ? 164 ASN A O   1 
ATOM 1843 C CB  . ASN B 2 163 ? 111.023 83.165  138.611 1.00 81.83  ? 164 ASN A CB  1 
ATOM 1844 C CG  . ASN B 2 163 ? 111.750 82.067  137.869 1.00 87.64  ? 164 ASN A CG  1 
ATOM 1845 O OD1 . ASN B 2 163 ? 112.576 82.334  136.992 1.00 90.49  ? 164 ASN A OD1 1 
ATOM 1846 N ND2 . ASN B 2 163 ? 111.466 80.821  138.214 1.00 97.13  ? 164 ASN A ND2 1 
ATOM 1847 N N   . SER B 2 164 ? 108.827 85.197  138.487 1.00 91.02  ? 165 SER A N   1 
ATOM 1848 C CA  . SER B 2 164 ? 107.761 86.083  138.932 1.00 87.59  ? 165 SER A CA  1 
ATOM 1849 C C   . SER B 2 164 ? 106.980 85.465  140.084 1.00 89.69  ? 165 SER A C   1 
ATOM 1850 O O   . SER B 2 164 ? 105.751 85.535  140.135 1.00 97.44  ? 165 SER A O   1 
ATOM 1851 C CB  . SER B 2 164 ? 106.830 86.432  137.776 1.00 96.83  ? 165 SER A CB  1 
ATOM 1852 O OG  . SER B 2 164 ? 107.478 87.280  136.845 1.00 103.68 ? 165 SER A OG  1 
ATOM 1853 N N   . LEU B 2 165 ? 107.702 84.883  141.052 1.00 84.74  ? 166 LEU A N   1 
ATOM 1854 C CA  . LEU B 2 165 ? 107.075 84.258  142.249 1.00 86.97  ? 166 LEU A CA  1 
ATOM 1855 C C   . LEU B 2 165 ? 106.679 85.363  143.236 1.00 91.55  ? 166 LEU A C   1 
ATOM 1856 O O   . LEU B 2 165 ? 107.566 86.157  143.593 1.00 91.76  ? 166 LEU A O   1 
ATOM 1857 C CB  . LEU B 2 165 ? 108.027 83.257  142.900 1.00 88.21  ? 166 LEU A CB  1 
ATOM 1858 C CG  . LEU B 2 165 ? 108.551 82.144  141.991 1.00 80.67  ? 166 LEU A CG  1 
ATOM 1859 C CD1 . LEU B 2 165 ? 109.750 81.441  142.591 1.00 78.49  ? 166 LEU A CD1 1 
ATOM 1860 C CD2 . LEU B 2 165 ? 107.429 81.170  141.737 1.00 88.76  ? 166 LEU A CD2 1 
ATOM 1861 N N   . THR B 2 166 ? 105.428 85.389  143.700 1.00 101.14 ? 167 THR A N   1 
ATOM 1862 C CA  . THR B 2 166 ? 104.915 86.430  144.579 1.00 104.88 ? 167 THR A CA  1 
ATOM 1863 C C   . THR B 2 166 ? 105.257 86.188  146.040 1.00 107.71 ? 167 THR A C   1 
ATOM 1864 O O   . THR B 2 166 ? 105.318 87.144  146.821 1.00 108.90 ? 167 THR A O   1 
ATOM 1865 C CB  . THR B 2 166 ? 103.396 86.551  144.430 1.00 106.74 ? 167 THR A CB  1 
ATOM 1866 O OG1 . THR B 2 166 ? 102.766 85.400  145.003 1.00 107.57 ? 167 THR A OG1 1 
ATOM 1867 C CG2 . THR B 2 166 ? 103.015 86.652  142.962 1.00 103.33 ? 167 THR A CG2 1 
ATOM 1868 N N   . GLU B 2 167 ? 105.481 84.935  146.429 1.00 108.77 ? 168 GLU A N   1 
ATOM 1869 C CA  . GLU B 2 167 ? 105.820 84.610  147.806 1.00 106.41 ? 168 GLU A CA  1 
ATOM 1870 C C   . GLU B 2 167 ? 106.634 83.325  147.823 1.00 107.33 ? 168 GLU A C   1 
ATOM 1871 O O   . GLU B 2 167 ? 106.608 82.537  146.875 1.00 111.18 ? 168 GLU A O   1 
ATOM 1872 C CB  . GLU B 2 167 ? 104.565 84.475  148.675 1.00 107.49 ? 168 GLU A CB  1 
ATOM 1873 C CG  . GLU B 2 167 ? 103.736 83.239  148.382 1.00 108.19 ? 168 GLU A CG  1 
ATOM 1874 C CD  . GLU B 2 167 ? 103.936 82.151  149.415 1.00 115.49 ? 168 GLU A CD  1 
ATOM 1875 O OE1 . GLU B 2 167 ? 104.439 82.464  150.514 1.00 120.10 ? 168 GLU A OE1 1 
ATOM 1876 O OE2 . GLU B 2 167 ? 103.594 80.985  149.129 1.00 111.26 ? 168 GLU A OE2 1 
ATOM 1877 N N   . VAL B 2 168 ? 107.359 83.124  148.915 1.00 92.82  ? 169 VAL A N   1 
ATOM 1878 C CA  . VAL B 2 168 ? 108.244 81.960  149.026 1.00 92.30  ? 169 VAL A CA  1 
ATOM 1879 C C   . VAL B 2 168 ? 107.403 80.698  149.191 1.00 99.32  ? 169 VAL A C   1 
ATOM 1880 O O   . VAL B 2 168 ? 106.563 80.633  150.106 1.00 103.87 ? 169 VAL A O   1 
ATOM 1881 C CB  . VAL B 2 168 ? 109.207 82.136  150.199 1.00 87.10  ? 169 VAL A CB  1 
ATOM 1882 C CG1 . VAL B 2 168 ? 109.854 80.810  150.558 1.00 91.64  ? 169 VAL A CG1 1 
ATOM 1883 C CG2 . VAL B 2 168 ? 110.262 83.168  149.860 1.00 88.05  ? 169 VAL A CG2 1 
ATOM 1884 N N   . PRO B 2 169 ? 107.562 79.662  148.324 1.00 102.04 ? 170 PRO A N   1 
ATOM 1885 C CA  . PRO B 2 169 ? 106.830 78.413  148.483 1.00 104.61 ? 170 PRO A CA  1 
ATOM 1886 C C   . PRO B 2 169 ? 107.360 77.686  149.703 1.00 101.54 ? 170 PRO A C   1 
ATOM 1887 O O   . PRO B 2 169 ? 108.544 77.334  149.689 1.00 101.08 ? 170 PRO A O   1 
ATOM 1888 C CB  . PRO B 2 169 ? 107.078 77.634  147.185 1.00 99.88  ? 170 PRO A CB  1 
ATOM 1889 C CG  . PRO B 2 169 ? 108.385 78.176  146.668 1.00 94.19  ? 170 PRO A CG  1 
ATOM 1890 C CD  . PRO B 2 169 ? 108.449 79.612  147.161 1.00 92.55  ? 170 PRO A CD  1 
ATOM 1891 N N   . VAL B 2 170 ? 106.537 77.461  150.729 1.00 102.98 ? 171 VAL A N   1 
ATOM 1892 C CA  . VAL B 2 170 ? 107.003 76.857  151.973 1.00 99.83  ? 171 VAL A CA  1 
ATOM 1893 C C   . VAL B 2 170 ? 106.957 75.333  151.898 1.00 101.06 ? 171 VAL A C   1 
ATOM 1894 O O   . VAL B 2 170 ? 107.919 74.656  152.277 1.00 104.40 ? 171 VAL A O   1 
ATOM 1895 C CB  . VAL B 2 170 ? 106.206 77.411  153.171 1.00 104.21 ? 171 VAL A CB  1 
ATOM 1896 C CG1 . VAL B 2 170 ? 106.350 78.920  153.233 1.00 102.70 ? 171 VAL A CG1 1 
ATOM 1897 C CG2 . VAL B 2 170 ? 104.730 77.052  153.078 1.00 103.31 ? 171 VAL A CG2 1 
ATOM 1898 N N   . HIS B 2 171 ? 105.850 74.768  151.415 1.00 115.19 ? 172 HIS A N   1 
ATOM 1899 C CA  . HIS B 2 171 ? 105.737 73.312  151.344 1.00 118.03 ? 172 HIS A CA  1 
ATOM 1900 C C   . HIS B 2 171 ? 106.742 72.679  150.389 1.00 123.09 ? 172 HIS A C   1 
ATOM 1901 O O   . HIS B 2 171 ? 107.413 71.711  150.791 1.00 127.54 ? 172 HIS A O   1 
ATOM 1902 C CB  . HIS B 2 171 ? 104.290 72.950  150.994 1.00 117.38 ? 172 HIS A CB  1 
ATOM 1903 C CG  . HIS B 2 171 ? 103.402 72.792  152.188 1.00 121.89 ? 172 HIS A CG  1 
ATOM 1904 N ND1 . HIS B 2 171 ? 103.136 71.567  152.761 1.00 125.35 ? 172 HIS A ND1 1 
ATOM 1905 C CD2 . HIS B 2 171 ? 102.720 73.706  152.917 1.00 121.22 ? 172 HIS A CD2 1 
ATOM 1906 C CE1 . HIS B 2 171 ? 102.327 71.734  153.792 1.00 125.22 ? 172 HIS A CE1 1 
ATOM 1907 N NE2 . HIS B 2 171 ? 102.059 73.022  153.909 1.00 125.58 ? 172 HIS A NE2 1 
ATOM 1908 N N   . PRO B 2 172 ? 106.891 73.134  149.137 1.00 110.59 ? 173 PRO A N   1 
ATOM 1909 C CA  . PRO B 2 172 ? 107.885 72.492  148.260 1.00 112.09 ? 173 PRO A CA  1 
ATOM 1910 C C   . PRO B 2 172 ? 109.300 72.559  148.804 1.00 114.72 ? 173 PRO A C   1 
ATOM 1911 O O   . PRO B 2 172 ? 110.054 71.587  148.677 1.00 112.30 ? 173 PRO A O   1 
ATOM 1912 C CB  . PRO B 2 172 ? 107.739 73.268  146.944 1.00 109.87 ? 173 PRO A CB  1 
ATOM 1913 C CG  . PRO B 2 172 ? 106.371 73.836  146.995 1.00 111.58 ? 173 PRO A CG  1 
ATOM 1914 C CD  . PRO B 2 172 ? 106.157 74.194  148.423 1.00 106.81 ? 173 PRO A CD  1 
ATOM 1915 N N   . LEU B 2 173 ? 109.685 73.684  149.408 1.00 101.87 ? 174 LEU A N   1 
ATOM 1916 C CA  . LEU B 2 173 ? 111.008 73.767  150.015 1.00 96.55  ? 174 LEU A CA  1 
ATOM 1917 C C   . LEU B 2 173 ? 111.126 72.820  151.202 1.00 99.55  ? 174 LEU A C   1 
ATOM 1918 O O   . LEU B 2 173 ? 112.153 72.154  151.371 1.00 105.45 ? 174 LEU A O   1 
ATOM 1919 C CB  . LEU B 2 173 ? 111.304 75.205  150.436 1.00 95.82  ? 174 LEU A CB  1 
ATOM 1920 C CG  . LEU B 2 173 ? 111.561 76.199  149.302 1.00 97.12  ? 174 LEU A CG  1 
ATOM 1921 C CD1 . LEU B 2 173 ? 112.415 77.352  149.790 1.00 100.47 ? 174 LEU A CD1 1 
ATOM 1922 C CD2 . LEU B 2 173 ? 112.218 75.517  148.116 1.00 94.97  ? 174 LEU A CD2 1 
ATOM 1923 N N   . SER B 2 174 ? 110.080 72.735  152.026 1.00 114.26 ? 175 SER A N   1 
ATOM 1924 C CA  . SER B 2 174 ? 110.091 71.811  153.152 1.00 118.52 ? 175 SER A CA  1 
ATOM 1925 C C   . SER B 2 174 ? 110.132 70.357  152.707 1.00 113.58 ? 175 SER A C   1 
ATOM 1926 O O   . SER B 2 174 ? 110.502 69.489  153.503 1.00 111.11 ? 175 SER A O   1 
ATOM 1927 C CB  . SER B 2 174 ? 108.867 72.047  154.036 1.00 119.66 ? 175 SER A CB  1 
ATOM 1928 O OG  . SER B 2 174 ? 107.796 71.203  153.654 1.00 114.84 ? 175 SER A OG  1 
ATOM 1929 N N   . ASN B 2 175 ? 109.751 70.074  151.459 1.00 108.46 ? 176 ASN A N   1 
ATOM 1930 C CA  . ASN B 2 175 ? 109.747 68.694  150.982 1.00 109.24 ? 176 ASN A CA  1 
ATOM 1931 C C   . ASN B 2 175 ? 111.112 68.014  150.990 1.00 111.67 ? 176 ASN A C   1 
ATOM 1932 O O   . ASN B 2 175 ? 111.232 66.856  151.404 1.00 113.24 ? 176 ASN A O   1 
ATOM 1933 C CB  . ASN B 2 175 ? 109.128 68.627  149.587 1.00 111.58 ? 176 ASN A CB  1 
ATOM 1934 C CG  . ASN B 2 175 ? 107.777 67.948  149.582 1.00 119.78 ? 176 ASN A CG  1 
ATOM 1935 O OD1 . ASN B 2 175 ? 107.404 67.278  150.544 1.00 117.85 ? 176 ASN A OD1 1 
ATOM 1936 N ND2 . ASN B 2 175 ? 107.033 68.120  148.496 1.00 120.45 ? 176 ASN A ND2 1 
ATOM 1937 N N   . LEU B 2 176 ? 112.126 68.714  150.429 1.00 106.37 ? 177 LEU A N   1 
ATOM 1938 C CA  . LEU B 2 176 ? 113.505 68.160  150.282 1.00 109.13 ? 177 LEU A CA  1 
ATOM 1939 C C   . LEU B 2 176 ? 114.457 68.807  151.318 1.00 109.71 ? 177 LEU A C   1 
ATOM 1940 O O   . LEU B 2 176 ? 114.543 70.051  151.332 1.00 107.67 ? 177 LEU A O   1 
ATOM 1941 C CB  . LEU B 2 176 ? 114.039 68.321  148.857 1.00 102.50 ? 177 LEU A CB  1 
ATOM 1942 C CG  . LEU B 2 176 ? 114.215 69.734  148.294 1.00 98.70  ? 177 LEU A CG  1 
ATOM 1943 C CD1 . LEU B 2 176 ? 115.499 70.360  148.801 1.00 100.31 ? 177 LEU A CD1 1 
ATOM 1944 C CD2 . LEU B 2 176 ? 114.245 69.666  146.782 1.00 99.14  ? 177 LEU A CD2 1 
ATOM 1945 N N   . PRO B 2 177 ? 115.136 68.025  152.199 1.00 104.91 ? 178 PRO A N   1 
ATOM 1946 C CA  . PRO B 2 177 ? 115.960 68.638  153.249 1.00 104.94 ? 178 PRO A CA  1 
ATOM 1947 C C   . PRO B 2 177 ? 117.444 68.703  152.916 1.00 102.62 ? 178 PRO A C   1 
ATOM 1948 O O   . PRO B 2 177 ? 118.223 69.267  153.690 1.00 105.15 ? 178 PRO A O   1 
ATOM 1949 C CB  . PRO B 2 177 ? 115.701 67.650  154.389 1.00 102.88 ? 178 PRO A CB  1 
ATOM 1950 C CG  . PRO B 2 177 ? 115.459 66.340  153.678 1.00 100.07 ? 178 PRO A CG  1 
ATOM 1951 C CD  . PRO B 2 177 ? 114.936 66.652  152.286 1.00 98.49  ? 178 PRO A CD  1 
ATOM 1952 N N   . THR B 2 178 ? 117.856 68.136  151.786 1.00 95.96  ? 179 THR A N   1 
ATOM 1953 C CA  . THR B 2 178 ? 119.272 67.990  151.472 1.00 95.19  ? 179 THR A CA  1 
ATOM 1954 C C   . THR B 2 178 ? 119.822 69.135  150.632 1.00 95.55  ? 179 THR A C   1 
ATOM 1955 O O   . THR B 2 178 ? 120.952 69.038  150.144 1.00 96.41  ? 179 THR A O   1 
ATOM 1956 C CB  . THR B 2 178 ? 119.522 66.662  150.753 1.00 97.80  ? 179 THR A CB  1 
ATOM 1957 O OG1 . THR B 2 178 ? 119.319 66.833  149.345 1.00 103.31 ? 179 THR A OG1 1 
ATOM 1958 C CG2 . THR B 2 178 ? 118.579 65.591  151.272 1.00 97.61  ? 179 THR A CG2 1 
ATOM 1959 N N   . LEU B 2 179 ? 119.032 70.197  150.431 1.00 91.38  ? 180 LEU A N   1 
ATOM 1960 C CA  . LEU B 2 179 ? 119.463 71.327  149.570 1.00 89.21  ? 180 LEU A CA  1 
ATOM 1961 C C   . LEU B 2 179 ? 120.653 72.033  150.223 1.00 93.90  ? 180 LEU A C   1 
ATOM 1962 O O   . LEU B 2 179 ? 120.632 72.168  151.462 1.00 101.81 ? 180 LEU A O   1 
ATOM 1963 C CB  . LEU B 2 179 ? 118.345 72.330  149.286 1.00 87.54  ? 180 LEU A CB  1 
ATOM 1964 C CG  . LEU B 2 179 ? 118.584 73.266  148.097 1.00 89.11  ? 180 LEU A CG  1 
ATOM 1965 C CD1 . LEU B 2 179 ? 118.519 72.544  146.763 1.00 93.03  ? 180 LEU A CD1 1 
ATOM 1966 C CD2 . LEU B 2 179 ? 117.584 74.399  148.125 1.00 92.21  ? 180 LEU A CD2 1 
ATOM 1967 N N   . GLN B 2 180 ? 121.624 72.476  149.424 1.00 79.81  ? 181 GLN A N   1 
ATOM 1968 C CA  . GLN B 2 180 ? 122.808 73.188  149.880 1.00 77.91  ? 181 GLN A CA  1 
ATOM 1969 C C   . GLN B 2 180 ? 122.916 74.603  149.340 1.00 85.14  ? 181 GLN A C   1 
ATOM 1970 O O   . GLN B 2 180 ? 123.469 75.465  150.023 1.00 97.76  ? 181 GLN A O   1 
ATOM 1971 C CB  . GLN B 2 180 ? 124.080 72.418  149.496 1.00 81.70  ? 181 GLN A CB  1 
ATOM 1972 C CG  . GLN B 2 180 ? 124.644 71.558  150.610 1.00 89.55  ? 181 GLN A CG  1 
ATOM 1973 C CD  . GLN B 2 180 ? 125.468 70.401  150.087 1.00 92.77  ? 181 GLN A CD  1 
ATOM 1974 O OE1 . GLN B 2 180 ? 124.973 69.283  149.951 1.00 96.14  ? 181 GLN A OE1 1 
ATOM 1975 N NE2 . GLN B 2 180 ? 126.733 70.665  149.789 1.00 88.79  ? 181 GLN A NE2 1 
ATOM 1976 N N   . ALA B 2 181 ? 122.410 74.867  148.140 1.00 76.00  ? 182 ALA A N   1 
ATOM 1977 C CA  . ALA B 2 181 ? 122.426 76.201  147.560 1.00 79.01  ? 182 ALA A CA  1 
ATOM 1978 C C   . ALA B 2 181 ? 121.053 76.518  146.992 1.00 82.00  ? 182 ALA A C   1 
ATOM 1979 O O   . ALA B 2 181 ? 120.422 75.666  146.360 1.00 90.13  ? 182 ALA A O   1 
ATOM 1980 C CB  . ALA B 2 181 ? 123.488 76.322  146.465 1.00 77.14  ? 182 ALA A CB  1 
ATOM 1981 N N   . LEU B 2 182 ? 120.594 77.745  147.220 1.00 75.75  ? 183 LEU A N   1 
ATOM 1982 C CA  . LEU B 2 182 ? 119.286 78.172  146.749 1.00 67.88  ? 183 LEU A CA  1 
ATOM 1983 C C   . LEU B 2 182 ? 119.390 79.648  146.405 1.00 70.31  ? 183 LEU A C   1 
ATOM 1984 O O   . LEU B 2 182 ? 120.032 80.417  147.124 1.00 79.25  ? 183 LEU A O   1 
ATOM 1985 C CB  . LEU B 2 182 ? 118.213 77.978  147.824 1.00 70.52  ? 183 LEU A CB  1 
ATOM 1986 C CG  . LEU B 2 182 ? 116.808 78.479  147.495 1.00 62.72  ? 183 LEU A CG  1 
ATOM 1987 C CD1 . LEU B 2 182 ? 116.293 77.816  146.235 1.00 69.15  ? 183 LEU A CD1 1 
ATOM 1988 C CD2 . LEU B 2 182 ? 115.865 78.226  148.654 1.00 64.34  ? 183 LEU A CD2 1 
ATOM 1989 N N   . THR B 2 183 ? 118.777 80.036  145.282 1.00 65.11  ? 184 THR A N   1 
ATOM 1990 C CA  . THR B 2 183 ? 118.721 81.443  144.845 1.00 66.68  ? 184 THR A CA  1 
ATOM 1991 C C   . THR B 2 183 ? 117.284 81.740  144.493 1.00 69.69  ? 184 THR A C   1 
ATOM 1992 O O   . THR B 2 183 ? 116.643 80.853  143.899 1.00 76.91  ? 184 THR A O   1 
ATOM 1993 C CB  . THR B 2 183 ? 119.680 81.709  143.683 1.00 58.65  ? 184 THR A CB  1 
ATOM 1994 O OG1 . THR B 2 183 ? 119.372 83.027  143.243 1.00 64.09  ? 184 THR A OG1 1 
ATOM 1995 C CG2 . THR B 2 183 ? 119.529 80.754  142.514 1.00 64.64  ? 184 THR A CG2 1 
ATOM 1996 N N   . LEU B 2 184 ? 116.771 82.908  144.878 1.00 60.48  ? 185 LEU A N   1 
ATOM 1997 C CA  . LEU B 2 184 ? 115.407 83.335  144.592 1.00 46.24  ? 185 LEU A CA  1 
ATOM 1998 C C   . LEU B 2 184 ? 115.401 84.806  144.201 1.00 56.02  ? 185 LEU A C   1 
ATOM 1999 O O   . LEU B 2 184 ? 114.422 85.515  144.442 1.00 67.22  ? 185 LEU A O   1 
ATOM 2000 C CB  . LEU B 2 184 ? 114.536 83.108  145.827 1.00 41.73  ? 185 LEU A CB  1 
ATOM 2001 C CG  . LEU B 2 184 ? 114.066 81.676  146.082 1.00 47.23  ? 185 LEU A CG  1 
ATOM 2002 C CD1 . LEU B 2 184 ? 113.623 81.505  147.520 1.00 57.28  ? 185 LEU A CD1 1 
ATOM 2003 C CD2 . LEU B 2 184 ? 112.942 81.317  145.138 1.00 66.27  ? 185 LEU A CD2 1 
ATOM 2004 N N   . ALA B 2 185 ? 116.488 85.276  143.599 1.00 50.35  ? 186 ALA A N   1 
ATOM 2005 C CA  . ALA B 2 185 ? 116.632 86.684  143.278 1.00 56.08  ? 186 ALA A CA  1 
ATOM 2006 C C   . ALA B 2 185 ? 115.699 87.082  142.137 1.00 64.50  ? 186 ALA A C   1 
ATOM 2007 O O   . ALA B 2 185 ? 115.005 86.254  141.544 1.00 78.37  ? 186 ALA A O   1 
ATOM 2008 C CB  . ALA B 2 185 ? 118.080 87.000  142.911 1.00 63.10  ? 186 ALA A CB  1 
ATOM 2009 N N   . LEU B 2 186 ? 115.681 88.383  141.848 1.00 77.44  ? 187 LEU A N   1 
ATOM 2010 C CA  . LEU B 2 186 ? 114.962 88.948  140.705 1.00 76.56  ? 187 LEU A CA  1 
ATOM 2011 C C   . LEU B 2 186 ? 113.530 88.423  140.624 1.00 76.13  ? 187 LEU A C   1 
ATOM 2012 O O   . LEU B 2 186 ? 113.059 87.982  139.574 1.00 85.26  ? 187 LEU A O   1 
ATOM 2013 C CB  . LEU B 2 186 ? 115.716 88.678  139.405 1.00 74.42  ? 187 LEU A CB  1 
ATOM 2014 C CG  . LEU B 2 186 ? 116.861 89.638  139.086 1.00 79.41  ? 187 LEU A CG  1 
ATOM 2015 C CD1 . LEU B 2 186 ? 118.182 89.065  139.562 1.00 84.77  ? 187 LEU A CD1 1 
ATOM 2016 C CD2 . LEU B 2 186 ? 116.909 89.937  137.600 1.00 82.96  ? 187 LEU A CD2 1 
ATOM 2017 N N   . ASN B 2 187 ? 112.833 88.471  141.755 1.00 72.31  ? 188 ASN A N   1 
ATOM 2018 C CA  . ASN B 2 187 ? 111.468 87.967  141.817 1.00 77.81  ? 188 ASN A CA  1 
ATOM 2019 C C   . ASN B 2 187 ? 110.537 89.031  142.377 1.00 86.94  ? 188 ASN A C   1 
ATOM 2020 O O   . ASN B 2 187 ? 110.937 90.187  142.546 1.00 93.10  ? 188 ASN A O   1 
ATOM 2021 C CB  . ASN B 2 187 ? 111.407 86.696  142.664 1.00 78.92  ? 188 ASN A CB  1 
ATOM 2022 C CG  . ASN B 2 187 ? 111.526 85.440  141.832 1.00 80.72  ? 188 ASN A CG  1 
ATOM 2023 O OD1 . ASN B 2 187 ? 110.592 84.648  141.746 1.00 82.96  ? 188 ASN A OD1 1 
ATOM 2024 N ND2 . ASN B 2 187 ? 112.680 85.254  141.208 1.00 86.92  ? 188 ASN A ND2 1 
ATOM 2025 N N   . LYS B 2 188 ? 109.292 88.659  142.663 1.00 84.58  ? 189 LYS A N   1 
ATOM 2026 C CA  . LYS B 2 188 ? 108.304 89.591  143.189 1.00 86.61  ? 189 LYS A CA  1 
ATOM 2027 C C   . LYS B 2 188 ? 107.853 89.193  144.589 1.00 91.64  ? 189 LYS A C   1 
ATOM 2028 O O   . LYS B 2 188 ? 106.701 89.416  144.964 1.00 101.40 ? 189 LYS A O   1 
ATOM 2029 C CB  . LYS B 2 188 ? 107.103 89.690  142.250 1.00 96.47  ? 189 LYS A CB  1 
ATOM 2030 C CG  . LYS B 2 188 ? 107.460 90.074  140.827 1.00 95.81  ? 189 LYS A CG  1 
ATOM 2031 C CD  . LYS B 2 188 ? 108.345 91.305  140.793 1.00 96.15  ? 189 LYS A CD  1 
ATOM 2032 C CE  . LYS B 2 188 ? 108.262 91.996  139.445 1.00 101.36 ? 189 LYS A CE  1 
ATOM 2033 N NZ  . LYS B 2 188 ? 108.182 91.013  138.330 1.00 102.77 ? 189 LYS A NZ  1 
ATOM 2034 N N   . ILE B 2 189 ? 108.749 88.592  145.370 1.00 85.46  ? 190 ILE A N   1 
ATOM 2035 C CA  . ILE B 2 189 ? 108.420 88.243  146.745 1.00 83.38  ? 190 ILE A CA  1 
ATOM 2036 C C   . ILE B 2 189 ? 108.396 89.509  147.587 1.00 87.57  ? 190 ILE A C   1 
ATOM 2037 O O   . ILE B 2 189 ? 109.314 90.336  147.519 1.00 88.34  ? 190 ILE A O   1 
ATOM 2038 C CB  . ILE B 2 189 ? 109.421 87.221  147.300 1.00 83.69  ? 190 ILE A CB  1 
ATOM 2039 C CG1 . ILE B 2 189 ? 109.582 86.053  146.331 1.00 86.68  ? 190 ILE A CG1 1 
ATOM 2040 C CG2 . ILE B 2 189 ? 108.958 86.708  148.649 1.00 87.02  ? 190 ILE A CG2 1 
ATOM 2041 C CD1 . ILE B 2 189 ? 110.789 85.195  146.615 1.00 87.00  ? 190 ILE A CD1 1 
ATOM 2042 N N   . SER B 2 190 ? 107.360 89.657  148.415 1.00 94.46  ? 191 SER A N   1 
ATOM 2043 C CA  . SER B 2 190 ? 107.189 90.892  149.213 1.00 96.72  ? 191 SER A CA  1 
ATOM 2044 C C   . SER B 2 190 ? 107.372 90.626  150.703 1.00 93.06  ? 191 SER A C   1 
ATOM 2045 O O   . SER B 2 190 ? 107.853 91.509  151.366 1.00 91.67  ? 191 SER A O   1 
ATOM 2046 C CB  . SER B 2 190 ? 105.868 91.483  148.966 1.00 99.04  ? 191 SER A CB  1 
ATOM 2047 O OG  . SER B 2 190 ? 105.143 91.644  150.176 1.00 101.88 ? 191 SER A OG  1 
ATOM 2048 N N   . SER B 2 191 ? 106.969 89.481  151.221 1.00 92.20  ? 192 SER A N   1 
ATOM 2049 C CA  . SER B 2 191 ? 107.166 89.161  152.625 1.00 95.47  ? 192 SER A CA  1 
ATOM 2050 C C   . SER B 2 191 ? 107.622 87.717  152.752 1.00 97.22  ? 192 SER A C   1 
ATOM 2051 O O   . SER B 2 191 ? 107.256 86.861  151.943 1.00 106.04 ? 192 SER A O   1 
ATOM 2052 C CB  . SER B 2 191 ? 105.886 89.381  153.440 1.00 99.54  ? 192 SER A CB  1 
ATOM 2053 O OG  . SER B 2 191 ? 105.792 88.449  154.502 1.00 101.12 ? 192 SER A OG  1 
ATOM 2054 N N   . ILE B 2 192 ? 108.425 87.455  153.777 1.00 77.34  ? 193 ILE A N   1 
ATOM 2055 C CA  . ILE B 2 192 ? 108.915 86.116  154.080 1.00 75.60  ? 193 ILE A CA  1 
ATOM 2056 C C   . ILE B 2 192 ? 108.161 85.618  155.311 1.00 77.78  ? 193 ILE A C   1 
ATOM 2057 O O   . ILE B 2 192 ? 108.352 86.154  156.412 1.00 84.32  ? 193 ILE A O   1 
ATOM 2058 C CB  . ILE B 2 192 ? 110.431 86.105  154.309 1.00 76.63  ? 193 ILE A CB  1 
ATOM 2059 C CG1 . ILE B 2 192 ? 111.152 86.756  153.126 1.00 76.01  ? 193 ILE A CG1 1 
ATOM 2060 C CG2 . ILE B 2 192 ? 110.924 84.683  154.526 1.00 81.64  ? 193 ILE A CG2 1 
ATOM 2061 C CD1 . ILE B 2 192 ? 111.520 85.799  152.019 1.00 83.50  ? 193 ILE A CD1 1 
ATOM 2062 N N   . PRO B 2 193 ? 107.300 84.613  155.180 1.00 85.96  ? 194 PRO A N   1 
ATOM 2063 C CA  . PRO B 2 193 ? 106.522 84.152  156.332 1.00 86.48  ? 194 PRO A CA  1 
ATOM 2064 C C   . PRO B 2 193 ? 107.380 83.366  157.311 1.00 86.21  ? 194 PRO A C   1 
ATOM 2065 O O   . PRO B 2 193 ? 108.486 82.921  156.999 1.00 96.64  ? 194 PRO A O   1 
ATOM 2066 C CB  . PRO B 2 193 ? 105.451 83.262  155.699 1.00 92.89  ? 194 PRO A CB  1 
ATOM 2067 C CG  . PRO B 2 193 ? 106.107 82.733  154.470 1.00 91.11  ? 194 PRO A CG  1 
ATOM 2068 C CD  . PRO B 2 193 ? 107.016 83.827  153.968 1.00 91.05  ? 194 PRO A CD  1 
ATOM 2069 N N   . ASP B 2 194 ? 106.844 83.204  158.518 1.00 103.43 ? 195 ASP A N   1 
ATOM 2070 C CA  . ASP B 2 194 ? 107.550 82.469  159.558 1.00 108.81 ? 195 ASP A CA  1 
ATOM 2071 C C   . ASP B 2 194 ? 107.749 81.015  159.151 1.00 113.19 ? 195 ASP A C   1 
ATOM 2072 O O   . ASP B 2 194 ? 106.879 80.403  158.526 1.00 114.21 ? 195 ASP A O   1 
ATOM 2073 C CB  . ASP B 2 194 ? 106.778 82.540  160.876 1.00 114.13 ? 195 ASP A CB  1 
ATOM 2074 C CG  . ASP B 2 194 ? 106.802 83.923  161.491 1.00 120.71 ? 195 ASP A CG  1 
ATOM 2075 O OD1 . ASP B 2 194 ? 107.746 84.221  162.252 1.00 118.97 ? 195 ASP A OD1 1 
ATOM 2076 O OD2 . ASP B 2 194 ? 105.876 84.714  161.214 1.00 124.53 ? 195 ASP A OD2 1 
ATOM 2077 N N   . PHE B 2 195 ? 108.912 80.468  159.511 1.00 110.54 ? 196 PHE A N   1 
ATOM 2078 C CA  . PHE B 2 195 ? 109.255 79.071  159.237 1.00 106.64 ? 196 PHE A CA  1 
ATOM 2079 C C   . PHE B 2 195 ? 109.193 78.762  157.743 1.00 105.50 ? 196 PHE A C   1 
ATOM 2080 O O   . PHE B 2 195 ? 108.816 77.664  157.332 1.00 106.31 ? 196 PHE A O   1 
ATOM 2081 C CB  . PHE B 2 195 ? 108.360 78.119  160.031 1.00 109.45 ? 196 PHE A CB  1 
ATOM 2082 C CG  . PHE B 2 195 ? 108.260 78.463  161.488 1.00 115.09 ? 196 PHE A CG  1 
ATOM 2083 C CD1 . PHE B 2 195 ? 109.304 78.182  162.351 1.00 110.38 ? 196 PHE A CD1 1 
ATOM 2084 C CD2 . PHE B 2 195 ? 107.126 79.076  161.992 1.00 114.44 ? 196 PHE A CD2 1 
ATOM 2085 C CE1 . PHE B 2 195 ? 109.218 78.500  163.692 1.00 110.19 ? 196 PHE A CE1 1 
ATOM 2086 C CE2 . PHE B 2 195 ? 107.034 79.397  163.333 1.00 111.46 ? 196 PHE A CE2 1 
ATOM 2087 C CZ  . PHE B 2 195 ? 108.081 79.109  164.183 1.00 111.39 ? 196 PHE A CZ  1 
ATOM 2088 N N   . ALA B 2 196 ? 109.561 79.747  156.922 1.00 88.43  ? 197 ALA A N   1 
ATOM 2089 C CA  . ALA B 2 196 ? 109.616 79.524  155.482 1.00 84.49  ? 197 ALA A CA  1 
ATOM 2090 C C   . ALA B 2 196 ? 110.693 78.508  155.122 1.00 91.19  ? 197 ALA A C   1 
ATOM 2091 O O   . ALA B 2 196 ? 110.481 77.649  154.259 1.00 95.45  ? 197 ALA A O   1 
ATOM 2092 C CB  . ALA B 2 196 ? 109.860 80.845  154.755 1.00 86.10  ? 197 ALA A CB  1 
ATOM 2093 N N   . PHE B 2 197 ? 111.849 78.588  155.776 1.00 94.99  ? 198 PHE A N   1 
ATOM 2094 C CA  . PHE B 2 197 ? 112.981 77.705  155.519 1.00 92.28  ? 198 PHE A CA  1 
ATOM 2095 C C   . PHE B 2 197 ? 113.289 76.836  156.734 1.00 93.71  ? 198 PHE A C   1 
ATOM 2096 O O   . PHE B 2 197 ? 114.448 76.642  157.101 1.00 98.62  ? 198 PHE A O   1 
ATOM 2097 C CB  . PHE B 2 197 ? 114.215 78.511  155.125 1.00 89.51  ? 198 PHE A CB  1 
ATOM 2098 C CG  . PHE B 2 197 ? 113.963 79.530  154.053 1.00 89.11  ? 198 PHE A CG  1 
ATOM 2099 C CD1 . PHE B 2 197 ? 113.753 79.143  152.743 1.00 89.62  ? 198 PHE A CD1 1 
ATOM 2100 C CD2 . PHE B 2 197 ? 113.944 80.879  154.356 1.00 87.81  ? 198 PHE A CD2 1 
ATOM 2101 C CE1 . PHE B 2 197 ? 113.526 80.082  151.758 1.00 91.59  ? 198 PHE A CE1 1 
ATOM 2102 C CE2 . PHE B 2 197 ? 113.717 81.821  153.374 1.00 86.08  ? 198 PHE A CE2 1 
ATOM 2103 C CZ  . PHE B 2 197 ? 113.509 81.421  152.075 1.00 90.70  ? 198 PHE A CZ  1 
ATOM 2104 N N   . THR B 2 198 ? 112.246 76.309  157.378 1.00 107.39 ? 199 THR A N   1 
ATOM 2105 C CA  . THR B 2 198 ? 112.440 75.584  158.630 1.00 110.07 ? 199 THR A CA  1 
ATOM 2106 C C   . THR B 2 198 ? 113.167 74.263  158.412 1.00 105.80 ? 199 THR A C   1 
ATOM 2107 O O   . THR B 2 198 ? 113.997 73.865  159.238 1.00 106.84 ? 199 THR A O   1 
ATOM 2108 C CB  . THR B 2 198 ? 111.094 75.345  159.315 1.00 113.78 ? 199 THR A CB  1 
ATOM 2109 O OG1 . THR B 2 198 ? 111.250 74.362  160.346 1.00 115.06 ? 199 THR A OG1 1 
ATOM 2110 C CG2 . THR B 2 198 ? 110.060 74.860  158.314 1.00 111.37 ? 199 THR A CG2 1 
ATOM 2111 N N   . ASN B 2 199 ? 112.875 73.569  157.317 1.00 100.23 ? 200 ASN A N   1 
ATOM 2112 C CA  . ASN B 2 199 ? 113.414 72.235  157.091 1.00 106.04 ? 200 ASN A CA  1 
ATOM 2113 C C   . ASN B 2 199 ? 114.666 72.129  156.230 1.00 111.65 ? 200 ASN A C   1 
ATOM 2114 O O   . ASN B 2 199 ? 115.146 71.014  156.003 1.00 112.77 ? 200 ASN A O   1 
ATOM 2115 C CB  . ASN B 2 199 ? 112.354 71.347  156.434 1.00 108.02 ? 200 ASN A CB  1 
ATOM 2116 C CG  . ASN B 2 199 ? 111.441 70.686  157.447 1.00 113.66 ? 200 ASN A CG  1 
ATOM 2117 O OD1 . ASN B 2 199 ? 110.416 71.244  157.835 1.00 108.50 ? 200 ASN A OD1 1 
ATOM 2118 N ND2 . ASN B 2 199 ? 111.813 69.488  157.884 1.00 113.82 ? 200 ASN A ND2 1 
ATOM 2119 N N   . LEU B 2 200 ? 115.204 73.248  155.749 1.00 108.37 ? 201 LEU A N   1 
ATOM 2120 C CA  . LEU B 2 200 ? 116.421 73.226  154.931 1.00 102.63 ? 201 LEU A CA  1 
ATOM 2121 C C   . LEU B 2 200 ? 117.613 73.365  155.893 1.00 100.27 ? 201 LEU A C   1 
ATOM 2122 O O   . LEU B 2 200 ? 118.227 74.419  156.068 1.00 102.56 ? 201 LEU A O   1 
ATOM 2123 C CB  . LEU B 2 200 ? 116.395 74.350  153.902 1.00 103.39 ? 201 LEU A CB  1 
ATOM 2124 C CG  . LEU B 2 200 ? 115.319 74.268  152.819 1.00 101.23 ? 201 LEU A CG  1 
ATOM 2125 C CD1 . LEU B 2 200 ? 115.320 75.517  151.962 1.00 98.22  ? 201 LEU A CD1 1 
ATOM 2126 C CD2 . LEU B 2 200 ? 115.527 73.037  151.959 1.00 100.22 ? 201 LEU A CD2 1 
ATOM 2127 N N   . SER B 2 201 ? 117.909 72.241  156.546 1.00 99.98  ? 202 SER A N   1 
ATOM 2128 C CA  . SER B 2 201 ? 118.932 72.237  157.587 1.00 105.27 ? 202 SER A CA  1 
ATOM 2129 C C   . SER B 2 201 ? 120.308 72.354  156.943 1.00 102.60 ? 202 SER A C   1 
ATOM 2130 O O   . SER B 2 201 ? 121.232 72.915  157.541 1.00 102.65 ? 202 SER A O   1 
ATOM 2131 C CB  . SER B 2 201 ? 118.811 70.920  158.351 1.00 99.64  ? 202 SER A CB  1 
ATOM 2132 O OG  . SER B 2 201 ? 118.861 69.817  157.464 1.00 98.26  ? 202 SER A OG  1 
ATOM 2133 N N   . SER B 2 202 ? 120.466 71.832  155.730 1.00 93.47  ? 203 SER A N   1 
ATOM 2134 C CA  . SER B 2 202 ? 121.768 71.757  155.080 1.00 91.85  ? 203 SER A CA  1 
ATOM 2135 C C   . SER B 2 202 ? 122.059 72.946  154.172 1.00 94.40  ? 203 SER A C   1 
ATOM 2136 O O   . SER B 2 202 ? 123.092 72.949  153.497 1.00 94.24  ? 203 SER A O   1 
ATOM 2137 C CB  . SER B 2 202 ? 121.880 70.459  154.277 1.00 94.70  ? 203 SER A CB  1 
ATOM 2138 O OG  . SER B 2 202 ? 121.394 69.357  155.023 1.00 102.95 ? 203 SER A OG  1 
ATOM 2139 N N   . LEU B 2 203 ? 121.179 73.944  154.134 1.00 91.63  ? 204 LEU A N   1 
ATOM 2140 C CA  . LEU B 2 203 ? 121.382 75.078  153.243 1.00 91.63  ? 204 LEU A CA  1 
ATOM 2141 C C   . LEU B 2 203 ? 122.654 75.831  153.610 1.00 94.53  ? 204 LEU A C   1 
ATOM 2142 O O   . LEU B 2 203 ? 122.987 75.987  154.787 1.00 101.68 ? 204 LEU A O   1 
ATOM 2143 C CB  . LEU B 2 203 ? 120.180 76.020  153.300 1.00 87.64  ? 204 LEU A CB  1 
ATOM 2144 C CG  . LEU B 2 203 ? 120.034 76.976  152.116 1.00 82.63  ? 204 LEU A CG  1 
ATOM 2145 C CD1 . LEU B 2 203 ? 119.937 76.199  150.817 1.00 88.23  ? 204 LEU A CD1 1 
ATOM 2146 C CD2 . LEU B 2 203 ? 118.828 77.877  152.297 1.00 86.86  ? 204 LEU A CD2 1 
ATOM 2147 N N   . VAL B 2 204 ? 123.370 76.299  152.587 1.00 81.66  ? 205 VAL A N   1 
ATOM 2148 C CA  . VAL B 2 204 ? 124.639 76.994  152.757 1.00 74.71  ? 205 VAL A CA  1 
ATOM 2149 C C   . VAL B 2 204 ? 124.594 78.394  152.159 1.00 80.15  ? 205 VAL A C   1 
ATOM 2150 O O   . VAL B 2 204 ? 125.016 79.366  152.792 1.00 97.49  ? 205 VAL A O   1 
ATOM 2151 C CB  . VAL B 2 204 ? 125.808 76.183  152.157 1.00 74.47  ? 205 VAL A CB  1 
ATOM 2152 C CG1 . VAL B 2 204 ? 127.075 77.017  152.125 1.00 82.16  ? 205 VAL A CG1 1 
ATOM 2153 C CG2 . VAL B 2 204 ? 126.021 74.911  152.951 1.00 78.50  ? 205 VAL A CG2 1 
ATOM 2154 N N   . VAL B 2 205 ? 124.083 78.518  150.938 1.00 66.84  ? 206 VAL A N   1 
ATOM 2155 C CA  . VAL B 2 205 ? 124.008 79.794  150.238 1.00 71.37  ? 206 VAL A CA  1 
ATOM 2156 C C   . VAL B 2 205 ? 122.551 80.083  149.915 1.00 78.39  ? 206 VAL A C   1 
ATOM 2157 O O   . VAL B 2 205 ? 121.855 79.232  149.350 1.00 91.86  ? 206 VAL A O   1 
ATOM 2158 C CB  . VAL B 2 205 ? 124.857 79.791  148.955 1.00 72.44  ? 206 VAL A CB  1 
ATOM 2159 C CG1 . VAL B 2 205 ? 124.830 81.159  148.301 1.00 72.17  ? 206 VAL A CG1 1 
ATOM 2160 C CG2 . VAL B 2 205 ? 126.281 79.379  149.266 1.00 83.37  ? 206 VAL A CG2 1 
ATOM 2161 N N   . LEU B 2 206 ? 122.094 81.280  150.272 1.00 75.05  ? 207 LEU A N   1 
ATOM 2162 C CA  . LEU B 2 206 ? 120.741 81.726  149.976 1.00 67.56  ? 207 LEU A CA  1 
ATOM 2163 C C   . LEU B 2 206 ? 120.803 83.104  149.340 1.00 75.40  ? 207 LEU A C   1 
ATOM 2164 O O   . LEU B 2 206 ? 121.376 84.032  149.917 1.00 84.32  ? 207 LEU A O   1 
ATOM 2165 C CB  . LEU B 2 206 ? 119.880 81.765  151.241 1.00 63.44  ? 207 LEU A CB  1 
ATOM 2166 C CG  . LEU B 2 206 ? 118.437 82.226  151.051 1.00 60.09  ? 207 LEU A CG  1 
ATOM 2167 C CD1 . LEU B 2 206 ? 117.752 81.385  149.994 1.00 66.47  ? 207 LEU A CD1 1 
ATOM 2168 C CD2 . LEU B 2 206 ? 117.683 82.152  152.363 1.00 70.02  ? 207 LEU A CD2 1 
ATOM 2169 N N   . HIS B 2 207 ? 120.302 83.219  148.116 1.00 69.51  ? 208 HIS A N   1 
ATOM 2170 C CA  . HIS B 2 207 ? 120.254 84.524  147.420 1.00 63.42  ? 208 HIS A CA  1 
ATOM 2171 C C   . HIS B 2 207 ? 118.801 84.973  147.445 1.00 69.27  ? 208 HIS A C   1 
ATOM 2172 O O   . HIS B 2 207 ? 117.964 84.077  147.343 1.00 81.19  ? 208 HIS A O   1 
ATOM 2173 C CB  . HIS B 2 207 ? 120.848 84.403  146.018 1.00 64.49  ? 208 HIS A CB  1 
ATOM 2174 C CG  . HIS B 2 207 ? 122.273 83.970  146.033 1.00 70.67  ? 208 HIS A CG  1 
ATOM 2175 N ND1 . HIS B 2 207 ? 123.236 84.617  146.775 1.00 80.62  ? 208 HIS A ND1 1 
ATOM 2176 C CD2 . HIS B 2 207 ? 122.894 82.959  145.419 1.00 66.80  ? 208 HIS A CD2 1 
ATOM 2177 C CE1 . HIS B 2 207 ? 124.401 84.011  146.600 1.00 78.09  ? 208 HIS A CE1 1 
ATOM 2178 N NE2 . HIS B 2 207 ? 124.216 83.004  145.777 1.00 73.88  ? 208 HIS A NE2 1 
ATOM 2179 N N   . LEU B 2 208 ? 118.529 86.221  147.798 1.00 63.97  ? 209 LEU A N   1 
ATOM 2180 C CA  . LEU B 2 208 ? 117.205 86.824  147.719 1.00 56.33  ? 209 LEU A CA  1 
ATOM 2181 C C   . LEU B 2 208 ? 117.268 88.274  147.254 1.00 68.03  ? 209 LEU A C   1 
ATOM 2182 O O   . LEU B 2 208 ? 116.324 89.034  147.496 1.00 71.58  ? 209 LEU A O   1 
ATOM 2183 C CB  . LEU B 2 208 ? 116.489 86.749  149.067 1.00 47.55  ? 209 LEU A CB  1 
ATOM 2184 C CG  . LEU B 2 208 ? 115.816 85.420  149.397 1.00 50.50  ? 209 LEU A CG  1 
ATOM 2185 C CD1 . LEU B 2 208 ? 115.984 85.090  150.865 1.00 68.98  ? 209 LEU A CD1 1 
ATOM 2186 C CD2 . LEU B 2 208 ? 114.349 85.476  149.031 1.00 68.05  ? 209 LEU A CD2 1 
ATOM 2187 N N   . HIS B 2 209 ? 118.350 88.674  146.592 1.00 71.36  ? 210 HIS A N   1 
ATOM 2188 C CA  . HIS B 2 209 ? 118.508 90.057  146.179 1.00 69.56  ? 210 HIS A CA  1 
ATOM 2189 C C   . HIS B 2 209 ? 117.555 90.389  145.035 1.00 74.81  ? 210 HIS A C   1 
ATOM 2190 O O   . HIS B 2 209 ? 116.851 89.529  144.503 1.00 84.79  ? 210 HIS A O   1 
ATOM 2191 C CB  . HIS B 2 209 ? 119.942 90.371  145.756 1.00 73.07  ? 210 HIS A CB  1 
ATOM 2192 C CG  . HIS B 2 209 ? 120.414 89.587  144.572 1.00 75.77  ? 210 HIS A CG  1 
ATOM 2193 N ND1 . HIS B 2 209 ? 120.854 88.285  144.669 1.00 79.18  ? 210 HIS A ND1 1 
ATOM 2194 C CD2 . HIS B 2 209 ? 120.518 89.921  143.264 1.00 74.70  ? 210 HIS A CD2 1 
ATOM 2195 C CE1 . HIS B 2 209 ? 121.214 87.852  143.474 1.00 72.35  ? 210 HIS A CE1 1 
ATOM 2196 N NE2 . HIS B 2 209 ? 121.020 88.826  142.604 1.00 73.53  ? 210 HIS A NE2 1 
ATOM 2197 N N   . ASN B 2 210 ? 117.526 91.672  144.672 1.00 81.96  ? 211 ASN A N   1 
ATOM 2198 C CA  . ASN B 2 210 ? 116.775 92.146  143.510 1.00 73.46  ? 211 ASN A CA  1 
ATOM 2199 C C   . ASN B 2 210 ? 115.291 91.811  143.622 1.00 81.98  ? 211 ASN A C   1 
ATOM 2200 O O   . ASN B 2 210 ? 114.634 91.489  142.632 1.00 94.56  ? 211 ASN A O   1 
ATOM 2201 C CB  . ASN B 2 210 ? 117.320 91.536  142.222 1.00 74.71  ? 211 ASN A CB  1 
ATOM 2202 C CG  . ASN B 2 210 ? 118.263 92.456  141.498 1.00 88.27  ? 211 ASN A CG  1 
ATOM 2203 O OD1 . ASN B 2 210 ? 118.428 92.370  140.283 1.00 86.80  ? 211 ASN A OD1 1 
ATOM 2204 N ND2 . ASN B 2 210 ? 118.903 93.340  142.245 1.00 96.28  ? 211 ASN A ND2 1 
ATOM 2205 N N   . ASN B 2 211 ? 114.756 91.896  144.828 1.00 78.65  ? 212 ASN A N   1 
ATOM 2206 C CA  . ASN B 2 211 ? 113.375 91.522  145.084 1.00 75.72  ? 212 ASN A CA  1 
ATOM 2207 C C   . ASN B 2 211 ? 112.607 92.742  145.582 1.00 86.66  ? 212 ASN A C   1 
ATOM 2208 O O   . ASN B 2 211 ? 113.117 93.865  145.594 1.00 99.33  ? 212 ASN A O   1 
ATOM 2209 C CB  . ASN B 2 211 ? 113.312 90.365  146.080 1.00 75.06  ? 212 ASN A CB  1 
ATOM 2210 C CG  . ASN B 2 211 ? 113.079 89.034  145.405 1.00 79.28  ? 212 ASN A CG  1 
ATOM 2211 O OD1 . ASN B 2 211 ? 113.407 88.857  144.233 1.00 81.95  ? 212 ASN A OD1 1 
ATOM 2212 N ND2 . ASN B 2 211 ? 112.510 88.088  146.139 1.00 82.98  ? 212 ASN A ND2 1 
ATOM 2213 N N   . LYS B 2 212 ? 111.363 92.516  145.983 1.00 78.83  ? 213 LYS A N   1 
ATOM 2214 C CA  . LYS B 2 212 ? 110.508 93.557  146.532 1.00 82.84  ? 213 LYS A CA  1 
ATOM 2215 C C   . LYS B 2 212 ? 110.124 93.223  147.965 1.00 86.41  ? 213 LYS A C   1 
ATOM 2216 O O   . LYS B 2 212 ? 109.004 93.481  148.408 1.00 90.25  ? 213 LYS A O   1 
ATOM 2217 C CB  . LYS B 2 212 ? 109.267 93.753  145.669 1.00 91.47  ? 213 LYS A CB  1 
ATOM 2218 C CG  . LYS B 2 212 ? 109.333 94.965  144.760 1.00 92.65  ? 213 LYS A CG  1 
ATOM 2219 C CD  . LYS B 2 212 ? 108.653 94.689  143.431 1.00 92.37  ? 213 LYS A CD  1 
ATOM 2220 C CE  . LYS B 2 212 ? 107.225 94.212  143.631 1.00 96.10  ? 213 LYS A CE  1 
ATOM 2221 N NZ  . LYS B 2 212 ? 106.465 95.093  144.560 1.00 96.67  ? 213 LYS A NZ  1 
ATOM 2222 N N   . ILE B 2 213 ? 111.058 92.636  148.704 1.00 89.98  ? 214 ILE A N   1 
ATOM 2223 C CA  . ILE B 2 213 ? 110.817 92.279  150.096 1.00 90.95  ? 214 ILE A CA  1 
ATOM 2224 C C   . ILE B 2 213 ? 110.962 93.535  150.941 1.00 91.14  ? 214 ILE A C   1 
ATOM 2225 O O   . ILE B 2 213 ? 111.915 94.304  150.773 1.00 93.77  ? 214 ILE A O   1 
ATOM 2226 C CB  . ILE B 2 213 ? 111.826 91.225  150.572 1.00 88.19  ? 214 ILE A CB  1 
ATOM 2227 C CG1 . ILE B 2 213 ? 112.029 90.157  149.497 1.00 88.39  ? 214 ILE A CG1 1 
ATOM 2228 C CG2 . ILE B 2 213 ? 111.347 90.590  151.861 1.00 86.37  ? 214 ILE A CG2 1 
ATOM 2229 C CD1 . ILE B 2 213 ? 112.787 88.942  149.976 1.00 84.04  ? 214 ILE A CD1 1 
ATOM 2230 N N   . ARG B 2 214 ? 110.014 93.747  151.850 1.00 99.23  ? 215 ARG A N   1 
ATOM 2231 C CA  . ARG B 2 214 ? 110.056 94.876  152.764 1.00 98.60  ? 215 ARG A CA  1 
ATOM 2232 C C   . ARG B 2 214 ? 109.712 94.530  154.211 1.00 97.59  ? 215 ARG A C   1 
ATOM 2233 O O   . ARG B 2 214 ? 109.938 95.357  155.102 1.00 98.42  ? 215 ARG A O   1 
ATOM 2234 C CB  . ARG B 2 214 ? 109.076 95.982  152.348 1.00 98.93  ? 215 ARG A CB  1 
ATOM 2235 C CG  . ARG B 2 214 ? 107.615 95.583  152.438 1.00 105.32 ? 215 ARG A CG  1 
ATOM 2236 C CD  . ARG B 2 214 ? 106.706 96.685  151.921 1.00 106.37 ? 215 ARG A CD  1 
ATOM 2237 N NE  . ARG B 2 214 ? 105.299 96.330  152.048 1.00 112.23 ? 215 ARG A NE  1 
ATOM 2238 C CZ  . ARG B 2 214 ? 104.633 95.585  151.176 1.00 112.99 ? 215 ARG A CZ  1 
ATOM 2239 N NH1 . ARG B 2 214 ? 105.215 95.107  150.089 1.00 109.12 ? 215 ARG A NH1 1 
ATOM 2240 N NH2 . ARG B 2 214 ? 103.350 95.314  151.401 1.00 110.84 ? 215 ARG A NH2 1 
ATOM 2241 N N   . SER B 2 215 ? 109.186 93.335  154.471 1.00 98.21  ? 216 SER A N   1 
ATOM 2242 C CA  . SER B 2 215 ? 108.846 92.904  155.818 1.00 102.72 ? 216 SER A CA  1 
ATOM 2243 C C   . SER B 2 215 ? 109.437 91.519  156.024 1.00 101.95 ? 216 SER A C   1 
ATOM 2244 O O   . SER B 2 215 ? 109.226 90.622  155.202 1.00 107.19 ? 216 SER A O   1 
ATOM 2245 C CB  . SER B 2 215 ? 107.346 92.888  156.130 1.00 101.77 ? 216 SER A CB  1 
ATOM 2246 O OG  . SER B 2 215 ? 106.683 93.971  155.502 1.00 104.53 ? 216 SER A OG  1 
ATOM 2247 N N   . LEU B 2 216 ? 110.195 91.325  157.112 1.00 93.07  ? 217 LEU A N   1 
ATOM 2248 C CA  . LEU B 2 216 ? 110.813 90.011  157.436 1.00 93.36  ? 217 LEU A CA  1 
ATOM 2249 C C   . LEU B 2 216 ? 110.360 89.594  158.839 1.00 98.13  ? 217 LEU A C   1 
ATOM 2250 O O   . LEU B 2 216 ? 110.616 90.368  159.783 1.00 106.67 ? 217 LEU A O   1 
ATOM 2251 C CB  . LEU B 2 216 ? 112.330 90.117  157.304 1.00 91.02  ? 217 LEU A CB  1 
ATOM 2252 C CG  . LEU B 2 216 ? 112.848 90.385  155.888 1.00 95.29  ? 217 LEU A CG  1 
ATOM 2253 C CD1 . LEU B 2 216 ? 114.348 90.580  155.869 1.00 95.82  ? 217 LEU A CD1 1 
ATOM 2254 C CD2 . LEU B 2 216 ? 112.455 89.263  154.955 1.00 100.07 ? 217 LEU A CD2 1 
ATOM 2255 N N   . SER B 2 217 ? 109.720 88.430  158.982 1.00 104.17 ? 218 SER A N   1 
ATOM 2256 C CA  . SER B 2 217 ? 109.177 87.962  160.244 1.00 106.44 ? 218 SER A CA  1 
ATOM 2257 C C   . SER B 2 217 ? 110.302 87.704  161.243 1.00 109.42 ? 218 SER A C   1 
ATOM 2258 O O   . SER B 2 217 ? 111.479 87.608  160.890 1.00 111.25 ? 218 SER A O   1 
ATOM 2259 C CB  . SER B 2 217 ? 108.349 86.697  160.039 1.00 110.13 ? 218 SER A CB  1 
ATOM 2260 O OG  . SER B 2 217 ? 109.119 85.541  160.315 1.00 113.61 ? 218 SER A OG  1 
ATOM 2261 N N   . GLN B 2 218 ? 109.921 87.591  162.517 1.00 111.30 ? 219 GLN A N   1 
ATOM 2262 C CA  . GLN B 2 218 ? 110.909 87.346  163.560 1.00 111.90 ? 219 GLN A CA  1 
ATOM 2263 C C   . GLN B 2 218 ? 111.509 85.951  163.453 1.00 115.33 ? 219 GLN A C   1 
ATOM 2264 O O   . GLN B 2 218 ? 112.642 85.731  163.893 1.00 116.35 ? 219 GLN A O   1 
ATOM 2265 C CB  . GLN B 2 218 ? 110.277 87.546  164.937 1.00 112.23 ? 219 GLN A CB  1 
ATOM 2266 C CG  . GLN B 2 218 ? 109.924 88.988  165.251 1.00 115.98 ? 219 GLN A CG  1 
ATOM 2267 C CD  . GLN B 2 218 ? 111.143 89.885  165.320 1.00 119.80 ? 219 GLN A CD  1 
ATOM 2268 O OE1 . GLN B 2 218 ? 111.161 90.974  164.745 1.00 121.99 ? 219 GLN A OE1 1 
ATOM 2269 N NE2 . GLN B 2 218 ? 112.170 89.434  166.030 1.00 119.53 ? 219 GLN A NE2 1 
ATOM 2270 N N   . HIS B 2 219 ? 110.773 85.001  162.877 1.00 114.32 ? 220 HIS A N   1 
ATOM 2271 C CA  . HIS B 2 219 ? 111.221 83.619  162.764 1.00 113.21 ? 220 HIS A CA  1 
ATOM 2272 C C   . HIS B 2 219 ? 111.265 83.157  161.312 1.00 111.68 ? 220 HIS A C   1 
ATOM 2273 O O   . HIS B 2 219 ? 111.123 81.966  161.028 1.00 109.86 ? 220 HIS A O   1 
ATOM 2274 C CB  . HIS B 2 219 ? 110.329 82.697  163.591 1.00 112.66 ? 220 HIS A CB  1 
ATOM 2275 C CG  . HIS B 2 219 ? 110.401 82.952  165.064 1.00 118.56 ? 220 HIS A CG  1 
ATOM 2276 N ND1 . HIS B 2 219 ? 111.454 82.523  165.842 1.00 120.26 ? 220 HIS A ND1 1 
ATOM 2277 C CD2 . HIS B 2 219 ? 109.552 83.595  165.900 1.00 117.40 ? 220 HIS A CD2 1 
ATOM 2278 C CE1 . HIS B 2 219 ? 111.250 82.889  167.095 1.00 118.28 ? 220 HIS A CE1 1 
ATOM 2279 N NE2 . HIS B 2 219 ? 110.103 83.541  167.157 1.00 118.20 ? 220 HIS A NE2 1 
ATOM 2280 N N   . CYS B 2 220 ? 111.460 84.090  160.379 1.00 96.99  ? 221 CYS A N   1 
ATOM 2281 C CA  . CYS B 2 220 ? 111.473 83.721  158.969 1.00 94.48  ? 221 CYS A CA  1 
ATOM 2282 C C   . CYS B 2 220 ? 112.711 82.913  158.605 1.00 98.92  ? 221 CYS A C   1 
ATOM 2283 O O   . CYS B 2 220 ? 112.663 82.096  157.679 1.00 106.55 ? 221 CYS A O   1 
ATOM 2284 C CB  . CYS B 2 220 ? 111.383 84.970  158.095 1.00 97.91  ? 221 CYS A CB  1 
ATOM 2285 S SG  . CYS B 2 220 ? 112.967 85.754  157.749 1.00 110.12 ? 221 CYS A SG  1 
ATOM 2286 N N   . PHE B 2 221 ? 113.822 83.121  159.312 1.00 87.52  ? 222 PHE A N   1 
ATOM 2287 C CA  . PHE B 2 221 ? 115.079 82.450  159.010 1.00 84.08  ? 222 PHE A CA  1 
ATOM 2288 C C   . PHE B 2 221 ? 115.399 81.331  159.995 1.00 86.85  ? 222 PHE A C   1 
ATOM 2289 O O   . PHE B 2 221 ? 116.572 80.990  160.174 1.00 92.39  ? 222 PHE A O   1 
ATOM 2290 C CB  . PHE B 2 221 ? 116.222 83.465  158.976 1.00 80.02  ? 222 PHE A CB  1 
ATOM 2291 C CG  . PHE B 2 221 ? 116.310 84.234  157.692 1.00 81.21  ? 222 PHE A CG  1 
ATOM 2292 C CD1 . PHE B 2 221 ? 116.013 83.628  156.485 1.00 85.72  ? 222 PHE A CD1 1 
ATOM 2293 C CD2 . PHE B 2 221 ? 116.687 85.564  157.690 1.00 82.30  ? 222 PHE A CD2 1 
ATOM 2294 C CE1 . PHE B 2 221 ? 116.092 84.335  155.303 1.00 87.90  ? 222 PHE A CE1 1 
ATOM 2295 C CE2 . PHE B 2 221 ? 116.765 86.275  156.512 1.00 81.60  ? 222 PHE A CE2 1 
ATOM 2296 C CZ  . PHE B 2 221 ? 116.468 85.659  155.318 1.00 86.91  ? 222 PHE A CZ  1 
ATOM 2297 N N   . ASP B 2 222 ? 114.385 80.760  160.637 1.00 109.31 ? 223 ASP A N   1 
ATOM 2298 C CA  . ASP B 2 222 ? 114.615 79.679  161.584 1.00 108.56 ? 223 ASP A CA  1 
ATOM 2299 C C   . ASP B 2 222 ? 115.058 78.412  160.863 1.00 106.72 ? 223 ASP A C   1 
ATOM 2300 O O   . ASP B 2 222 ? 114.588 78.105  159.765 1.00 113.11 ? 223 ASP A O   1 
ATOM 2301 C CB  . ASP B 2 222 ? 113.347 79.402  162.389 1.00 112.34 ? 223 ASP A CB  1 
ATOM 2302 C CG  . ASP B 2 222 ? 113.095 80.447  163.453 1.00 119.02 ? 223 ASP A CG  1 
ATOM 2303 O OD1 . ASP B 2 222 ? 113.705 81.533  163.376 1.00 120.29 ? 223 ASP A OD1 1 
ATOM 2304 O OD2 . ASP B 2 222 ? 112.284 80.183  164.365 1.00 118.54 ? 223 ASP A OD2 1 
ATOM 2305 N N   . GLY B 2 223 ? 115.974 77.676  161.490 1.00 103.03 ? 224 GLY A N   1 
ATOM 2306 C CA  . GLY B 2 223 ? 116.405 76.389  160.990 1.00 105.55 ? 224 GLY A CA  1 
ATOM 2307 C C   . GLY B 2 223 ? 117.573 76.418  160.029 1.00 109.42 ? 224 GLY A C   1 
ATOM 2308 O O   . GLY B 2 223 ? 118.103 75.350  159.696 1.00 109.63 ? 224 GLY A O   1 
ATOM 2309 N N   . LEU B 2 224 ? 117.998 77.596  159.575 1.00 107.24 ? 225 LEU A N   1 
ATOM 2310 C CA  . LEU B 2 224 ? 119.135 77.705  158.659 1.00 105.22 ? 225 LEU A CA  1 
ATOM 2311 C C   . LEU B 2 224 ? 120.432 77.748  159.467 1.00 106.54 ? 225 LEU A C   1 
ATOM 2312 O O   . LEU B 2 224 ? 121.138 78.755  159.538 1.00 113.20 ? 225 LEU A O   1 
ATOM 2313 C CB  . LEU B 2 224 ? 118.984 78.930  157.767 1.00 102.44 ? 225 LEU A CB  1 
ATOM 2314 C CG  . LEU B 2 224 ? 117.785 78.926  156.819 1.00 98.65  ? 225 LEU A CG  1 
ATOM 2315 C CD1 . LEU B 2 224 ? 117.796 80.163  155.941 1.00 100.53 ? 225 LEU A CD1 1 
ATOM 2316 C CD2 . LEU B 2 224 ? 117.786 77.671  155.972 1.00 99.34  ? 225 LEU A CD2 1 
ATOM 2317 N N   . ASP B 2 225 ? 120.738 76.607  160.086 1.00 107.09 ? 226 ASP A N   1 
ATOM 2318 C CA  . ASP B 2 225 ? 121.890 76.535  160.977 1.00 107.88 ? 226 ASP A CA  1 
ATOM 2319 C C   . ASP B 2 225 ? 123.207 76.569  160.214 1.00 110.47 ? 226 ASP A C   1 
ATOM 2320 O O   . ASP B 2 225 ? 124.206 77.078  160.734 1.00 110.57 ? 226 ASP A O   1 
ATOM 2321 C CB  . ASP B 2 225 ? 121.806 75.273  161.832 1.00 108.76 ? 226 ASP A CB  1 
ATOM 2322 C CG  . ASP B 2 225 ? 120.505 75.179  162.598 1.00 114.83 ? 226 ASP A CG  1 
ATOM 2323 O OD1 . ASP B 2 225 ? 119.766 76.184  162.640 1.00 114.54 ? 226 ASP A OD1 1 
ATOM 2324 O OD2 . ASP B 2 225 ? 120.219 74.100  163.159 1.00 116.81 ? 226 ASP A OD2 1 
ATOM 2325 N N   . ASN B 2 226 ? 123.237 76.038  158.995 1.00 102.61 ? 227 ASN A N   1 
ATOM 2326 C CA  . ASN B 2 226 ? 124.465 75.939  158.220 1.00 100.41 ? 227 ASN A CA  1 
ATOM 2327 C C   . ASN B 2 226 ? 124.609 77.048  157.188 1.00 99.20  ? 227 ASN A C   1 
ATOM 2328 O O   . ASN B 2 226 ? 125.532 76.998  156.369 1.00 96.70  ? 227 ASN A O   1 
ATOM 2329 C CB  . ASN B 2 226 ? 124.542 74.577  157.529 1.00 100.15 ? 227 ASN A CB  1 
ATOM 2330 C CG  . ASN B 2 226 ? 124.355 73.427  158.493 1.00 106.52 ? 227 ASN A CG  1 
ATOM 2331 O OD1 . ASN B 2 226 ? 123.515 73.485  159.390 1.00 110.72 ? 227 ASN A OD1 1 
ATOM 2332 N ND2 . ASN B 2 226 ? 125.139 72.371  158.314 1.00 103.98 ? 227 ASN A ND2 1 
ATOM 2333 N N   . LEU B 2 227 ? 123.723 78.041  157.202 1.00 83.30  ? 228 LEU A N   1 
ATOM 2334 C CA  . LEU B 2 227 ? 123.793 79.115  156.221 1.00 80.22  ? 228 LEU A CA  1 
ATOM 2335 C C   . LEU B 2 227 ? 125.090 79.897  156.377 1.00 81.97  ? 228 LEU A C   1 
ATOM 2336 O O   . LEU B 2 227 ? 125.492 80.240  157.490 1.00 92.78  ? 228 LEU A O   1 
ATOM 2337 C CB  . LEU B 2 227 ? 122.592 80.046  156.370 1.00 81.63  ? 228 LEU A CB  1 
ATOM 2338 C CG  . LEU B 2 227 ? 122.316 80.973  155.186 1.00 77.72  ? 228 LEU A CG  1 
ATOM 2339 C CD1 . LEU B 2 227 ? 121.903 80.167  153.970 1.00 83.37  ? 228 LEU A CD1 1 
ATOM 2340 C CD2 . LEU B 2 227 ? 121.250 81.993  155.538 1.00 77.15  ? 228 LEU A CD2 1 
ATOM 2341 N N   . GLU B 2 228 ? 125.746 80.175  155.252 1.00 85.57  ? 229 GLU A N   1 
ATOM 2342 C CA  . GLU B 2 228 ? 126.993 80.921  155.248 1.00 77.62  ? 229 GLU A CA  1 
ATOM 2343 C C   . GLU B 2 228 ? 126.978 82.133  154.332 1.00 79.52  ? 229 GLU A C   1 
ATOM 2344 O O   . GLU B 2 228 ? 127.937 82.911  154.354 1.00 89.74  ? 229 GLU A O   1 
ATOM 2345 C CB  . GLU B 2 228 ? 128.162 80.011  154.840 1.00 79.63  ? 229 GLU A CB  1 
ATOM 2346 C CG  . GLU B 2 228 ? 128.689 79.139  155.962 1.00 94.42  ? 229 GLU A CG  1 
ATOM 2347 C CD  . GLU B 2 228 ? 129.564 78.010  155.457 1.00 101.23 ? 229 GLU A CD  1 
ATOM 2348 O OE1 . GLU B 2 228 ? 130.210 78.185  154.403 1.00 103.37 ? 229 GLU A OE1 1 
ATOM 2349 O OE2 . GLU B 2 228 ? 129.609 76.950  156.115 1.00 99.37  ? 229 GLU A OE2 1 
ATOM 2350 N N   . THR B 2 229 ? 125.934 82.315  153.529 1.00 75.26  ? 230 THR A N   1 
ATOM 2351 C CA  . THR B 2 229 ? 125.843 83.462  152.637 1.00 74.13  ? 230 THR A CA  1 
ATOM 2352 C C   . THR B 2 229 ? 124.384 83.860  152.492 1.00 76.79  ? 230 THR A C   1 
ATOM 2353 O O   . THR B 2 229 ? 123.554 83.041  152.088 1.00 91.16  ? 230 THR A O   1 
ATOM 2354 C CB  . THR B 2 229 ? 126.439 83.147  151.263 1.00 83.82  ? 230 THR A CB  1 
ATOM 2355 O OG1 . THR B 2 229 ? 127.775 82.654  151.421 1.00 91.96  ? 230 THR A OG1 1 
ATOM 2356 C CG2 . THR B 2 229 ? 126.461 84.394  150.397 1.00 82.16  ? 230 THR A CG2 1 
ATOM 2357 N N   . LEU B 2 230 ? 124.080 85.112  152.819 1.00 72.60  ? 231 LEU A N   1 
ATOM 2358 C CA  . LEU B 2 230 ? 122.742 85.661  152.664 1.00 67.08  ? 231 LEU A CA  1 
ATOM 2359 C C   . LEU B 2 230 ? 122.840 86.946  151.859 1.00 70.34  ? 231 LEU A C   1 
ATOM 2360 O O   . LEU B 2 230 ? 123.671 87.807  152.161 1.00 78.46  ? 231 LEU A O   1 
ATOM 2361 C CB  . LEU B 2 230 ? 122.090 85.927  154.022 1.00 65.90  ? 231 LEU A CB  1 
ATOM 2362 C CG  . LEU B 2 230 ? 120.651 86.435  153.986 1.00 67.00  ? 231 LEU A CG  1 
ATOM 2363 C CD1 . LEU B 2 230 ? 119.781 85.470  153.212 1.00 68.42  ? 231 LEU A CD1 1 
ATOM 2364 C CD2 . LEU B 2 230 ? 120.122 86.623  155.393 1.00 67.74  ? 231 LEU A CD2 1 
ATOM 2365 N N   . ASP B 2 231 ? 122.000 87.072  150.836 1.00 80.54  ? 232 ASP A N   1 
ATOM 2366 C CA  . ASP B 2 231 ? 122.026 88.222  149.942 1.00 82.92  ? 232 ASP A CA  1 
ATOM 2367 C C   . ASP B 2 231 ? 120.638 88.844  149.901 1.00 85.07  ? 232 ASP A C   1 
ATOM 2368 O O   . ASP B 2 231 ? 119.687 88.214  149.427 1.00 93.22  ? 232 ASP A O   1 
ATOM 2369 C CB  . ASP B 2 231 ? 122.480 87.812  148.541 1.00 87.87  ? 232 ASP A CB  1 
ATOM 2370 C CG  . ASP B 2 231 ? 123.263 88.902  147.840 1.00 98.08  ? 232 ASP A CG  1 
ATOM 2371 O OD1 . ASP B 2 231 ? 122.639 89.825  147.279 1.00 95.09  ? 232 ASP A OD1 1 
ATOM 2372 O OD2 . ASP B 2 231 ? 124.510 88.837  147.849 1.00 103.47 ? 232 ASP A OD2 1 
ATOM 2373 N N   . LEU B 2 232 ? 120.524 90.079  150.398 1.00 65.71  ? 233 LEU A N   1 
ATOM 2374 C CA  . LEU B 2 232 ? 119.254 90.795  150.430 1.00 60.86  ? 233 LEU A CA  1 
ATOM 2375 C C   . LEU B 2 232 ? 119.351 92.154  149.747 1.00 71.18  ? 233 LEU A C   1 
ATOM 2376 O O   . LEU B 2 232 ? 118.563 93.052  150.054 1.00 74.70  ? 233 LEU A O   1 
ATOM 2377 C CB  . LEU B 2 232 ? 118.766 90.969  151.869 1.00 59.02  ? 233 LEU A CB  1 
ATOM 2378 C CG  . LEU B 2 232 ? 118.440 89.695  152.645 1.00 58.86  ? 233 LEU A CG  1 
ATOM 2379 C CD1 . LEU B 2 232 ? 117.864 90.033  154.005 1.00 70.04  ? 233 LEU A CD1 1 
ATOM 2380 C CD2 . LEU B 2 232 ? 117.473 88.839  151.862 1.00 62.61  ? 233 LEU A CD2 1 
ATOM 2381 N N   . ASN B 2 233 ? 120.291 92.290  148.851 1.00 75.50  ? 234 ASN A N   1 
ATOM 2382 C CA  . ASN B 2 233 ? 120.532 93.599  148.238 1.00 79.23  ? 234 ASN A CA  1 
ATOM 2383 C C   . ASN B 2 233 ? 119.334 94.001  147.389 1.00 82.52  ? 234 ASN A C   1 
ATOM 2384 O O   . ASN B 2 233 ? 118.514 93.151  147.182 1.00 92.33  ? 234 ASN A O   1 
ATOM 2385 C CB  . ASN B 2 233 ? 121.806 93.535  147.427 1.00 79.36  ? 234 ASN A CB  1 
ATOM 2386 C CG  . ASN B 2 233 ? 122.980 92.976  148.178 1.00 80.33  ? 234 ASN A CG  1 
ATOM 2387 O OD1 . ASN B 2 233 ? 123.079 93.157  149.387 1.00 85.81  ? 234 ASN A OD1 1 
ATOM 2388 N ND2 . ASN B 2 233 ? 123.881 92.309  147.481 1.00 79.99  ? 234 ASN A ND2 1 
ATOM 2389 N N   . TYR B 2 234 ? 119.172 95.257  147.018 1.00 76.15  ? 235 TYR A N   1 
ATOM 2390 C CA  . TYR B 2 234 ? 118.154 95.776  146.105 1.00 74.12  ? 235 TYR A CA  1 
ATOM 2391 C C   . TYR B 2 234 ? 116.755 95.314  146.516 1.00 79.04  ? 235 TYR A C   1 
ATOM 2392 O O   . TYR B 2 234 ? 116.028 94.676  145.754 1.00 87.15  ? 235 TYR A O   1 
ATOM 2393 C CB  . TYR B 2 234 ? 118.464 95.375  144.661 1.00 80.40  ? 235 TYR A CB  1 
ATOM 2394 C CG  . TYR B 2 234 ? 119.773 95.918  144.143 1.00 79.63  ? 235 TYR A CG  1 
ATOM 2395 C CD1 . TYR B 2 234 ? 119.897 97.250  143.781 1.00 80.12  ? 235 TYR A CD1 1 
ATOM 2396 C CD2 . TYR B 2 234 ? 120.884 95.099  144.019 1.00 83.73  ? 235 TYR A CD2 1 
ATOM 2397 C CE1 . TYR B 2 234 ? 121.090 97.751  143.308 1.00 84.73  ? 235 TYR A CE1 1 
ATOM 2398 C CE2 . TYR B 2 234 ? 122.082 95.590  143.548 1.00 82.51  ? 235 TYR A CE2 1 
ATOM 2399 C CZ  . TYR B 2 234 ? 122.179 96.916  143.194 1.00 85.94  ? 235 TYR A CZ  1 
ATOM 2400 O OH  . TYR B 2 234 ? 123.372 97.411  142.724 1.00 92.65  ? 235 TYR A OH  1 
ATOM 2401 N N   . ASN B 2 235 ? 116.388 95.654  147.748 1.00 77.26  ? 236 ASN A N   1 
ATOM 2402 C CA  . ASN B 2 235 ? 115.074 95.305  148.267 1.00 77.20  ? 236 ASN A CA  1 
ATOM 2403 C C   . ASN B 2 235 ? 114.365 96.546  148.784 1.00 82.05  ? 236 ASN A C   1 
ATOM 2404 O O   . ASN B 2 235 ? 114.839 97.668  148.582 1.00 88.84  ? 236 ASN A O   1 
ATOM 2405 C CB  . ASN B 2 235 ? 115.189 94.260  149.375 1.00 73.81  ? 236 ASN A CB  1 
ATOM 2406 C CG  . ASN B 2 235 ? 115.303 92.854  148.836 1.00 77.91  ? 236 ASN A CG  1 
ATOM 2407 O OD1 . ASN B 2 235 ? 115.668 92.648  147.681 1.00 79.16  ? 236 ASN A OD1 1 
ATOM 2408 N ND2 . ASN B 2 235 ? 114.987 91.875  149.671 1.00 85.75  ? 236 ASN A ND2 1 
ATOM 2409 N N   . ASN B 2 236 ? 113.226 96.358  149.443 1.00 88.78  ? 237 ASN A N   1 
ATOM 2410 C CA  . ASN B 2 236 ? 112.462 97.461  150.006 1.00 93.47  ? 237 ASN A CA  1 
ATOM 2411 C C   . ASN B 2 236 ? 112.425 97.399  151.528 1.00 100.28 ? 237 ASN A C   1 
ATOM 2412 O O   . ASN B 2 236 ? 111.437 97.797  152.149 1.00 108.44 ? 237 ASN A O   1 
ATOM 2413 C CB  . ASN B 2 236 ? 111.047 97.474  149.435 1.00 101.46 ? 237 ASN A CB  1 
ATOM 2414 C CG  . ASN B 2 236 ? 110.978 98.127  148.072 1.00 105.42 ? 237 ASN A CG  1 
ATOM 2415 O OD1 . ASN B 2 236 ? 111.994 98.282  147.395 1.00 104.35 ? 237 ASN A OD1 1 
ATOM 2416 N ND2 . ASN B 2 236 ? 109.777 98.515  147.662 1.00 106.21 ? 237 ASN A ND2 1 
ATOM 2417 N N   . LEU B 2 237 ? 113.493 96.898  152.139 1.00 90.06  ? 238 LEU A N   1 
ATOM 2418 C CA  . LEU B 2 237 ? 113.563 96.847  153.590 1.00 86.18  ? 238 LEU A CA  1 
ATOM 2419 C C   . LEU B 2 237 ? 113.736 98.252  154.148 1.00 87.39  ? 238 LEU A C   1 
ATOM 2420 O O   . LEU B 2 237 ? 114.591 99.012  153.687 1.00 91.76  ? 238 LEU A O   1 
ATOM 2421 C CB  . LEU B 2 237 ? 114.719 95.955  154.034 1.00 83.65  ? 238 LEU A CB  1 
ATOM 2422 C CG  . LEU B 2 237 ? 114.417 94.460  154.095 1.00 83.81  ? 238 LEU A CG  1 
ATOM 2423 C CD1 . LEU B 2 237 ? 115.701 93.663  154.235 1.00 87.37  ? 238 LEU A CD1 1 
ATOM 2424 C CD2 . LEU B 2 237 ? 113.464 94.159  155.237 1.00 88.70  ? 238 LEU A CD2 1 
ATOM 2425 N N   . GLY B 2 238 ? 112.920 98.597  155.138 1.00 95.52  ? 239 GLY A N   1 
ATOM 2426 C CA  . GLY B 2 238 ? 113.036 99.885  155.789 1.00 99.80  ? 239 GLY A CA  1 
ATOM 2427 C C   . GLY B 2 238 ? 113.438 99.740  157.240 1.00 101.01 ? 239 GLY A C   1 
ATOM 2428 O O   . GLY B 2 238 ? 114.119 100.604 157.800 1.00 100.21 ? 239 GLY A O   1 
ATOM 2429 N N   . GLU B 2 239 ? 113.016 98.641  157.854 1.00 106.02 ? 240 GLU A N   1 
ATOM 2430 C CA  . GLU B 2 239 ? 113.401 98.286  159.209 1.00 104.35 ? 240 GLU A CA  1 
ATOM 2431 C C   . GLU B 2 239 ? 114.447 97.181  159.156 1.00 107.26 ? 240 GLU A C   1 
ATOM 2432 O O   . GLU B 2 239 ? 114.457 96.362  158.234 1.00 109.80 ? 240 GLU A O   1 
ATOM 2433 C CB  . GLU B 2 239 ? 112.188 97.829  160.023 1.00 104.14 ? 240 GLU A CB  1 
ATOM 2434 C CG  . GLU B 2 239 ? 112.334 98.012  161.521 1.00 107.35 ? 240 GLU A CG  1 
ATOM 2435 C CD  . GLU B 2 239 ? 112.961 96.811  162.197 1.00 113.99 ? 240 GLU A CD  1 
ATOM 2436 O OE1 . GLU B 2 239 ? 112.256 95.796  162.383 1.00 109.53 ? 240 GLU A OE1 1 
ATOM 2437 O OE2 . GLU B 2 239 ? 114.158 96.883  162.545 1.00 117.24 ? 240 GLU A OE2 1 
ATOM 2438 N N   . PHE B 2 240 ? 115.334 97.169  160.144 1.00 96.37  ? 241 PHE A N   1 
ATOM 2439 C CA  . PHE B 2 240 ? 116.417 96.198  160.133 1.00 94.68  ? 241 PHE A CA  1 
ATOM 2440 C C   . PHE B 2 240 ? 115.872 94.787  160.348 1.00 101.31 ? 241 PHE A C   1 
ATOM 2441 O O   . PHE B 2 240 ? 115.015 94.573  161.211 1.00 103.63 ? 241 PHE A O   1 
ATOM 2442 C CB  . PHE B 2 240 ? 117.453 96.522  161.205 1.00 87.62  ? 241 PHE A CB  1 
ATOM 2443 C CG  . PHE B 2 240 ? 118.747 95.793  161.019 1.00 90.61  ? 241 PHE A CG  1 
ATOM 2444 C CD1 . PHE B 2 240 ? 119.699 96.263  160.135 1.00 90.87  ? 241 PHE A CD1 1 
ATOM 2445 C CD2 . PHE B 2 240 ? 118.999 94.622  161.708 1.00 98.51  ? 241 PHE A CD2 1 
ATOM 2446 C CE1 . PHE B 2 240 ? 120.887 95.589  159.954 1.00 93.98  ? 241 PHE A CE1 1 
ATOM 2447 C CE2 . PHE B 2 240 ? 120.184 93.942  161.529 1.00 98.97  ? 241 PHE A CE2 1 
ATOM 2448 C CZ  . PHE B 2 240 ? 121.129 94.426  160.652 1.00 95.99  ? 241 PHE A CZ  1 
ATOM 2449 N N   . PRO B 2 241 ? 116.347 93.806  159.580 1.00 101.96 ? 242 PRO A N   1 
ATOM 2450 C CA  . PRO B 2 241 ? 115.871 92.427  159.755 1.00 99.35  ? 242 PRO A CA  1 
ATOM 2451 C C   . PRO B 2 241 ? 116.315 91.805  161.068 1.00 96.07  ? 242 PRO A C   1 
ATOM 2452 O O   . PRO B 2 241 ? 117.512 91.624  161.309 1.00 95.37  ? 242 PRO A O   1 
ATOM 2453 C CB  . PRO B 2 241 ? 116.484 91.691  158.557 1.00 94.57  ? 242 PRO A CB  1 
ATOM 2454 C CG  . PRO B 2 241 ? 117.649 92.520  158.152 1.00 95.25  ? 242 PRO A CG  1 
ATOM 2455 C CD  . PRO B 2 241 ? 117.271 93.937  158.442 1.00 98.94  ? 242 PRO A CD  1 
ATOM 2456 N N   . GLN B 2 242 ? 115.352 91.472  161.926 1.00 104.45 ? 243 GLN A N   1 
ATOM 2457 C CA  . GLN B 2 242 ? 115.643 90.813  163.191 1.00 106.25 ? 243 GLN A CA  1 
ATOM 2458 C C   . GLN B 2 242 ? 115.897 89.321  163.040 1.00 104.95 ? 243 GLN A C   1 
ATOM 2459 O O   . GLN B 2 242 ? 116.353 88.687  163.996 1.00 108.79 ? 243 GLN A O   1 
ATOM 2460 C CB  . GLN B 2 242 ? 114.488 91.026  164.170 1.00 106.46 ? 243 GLN A CB  1 
ATOM 2461 C CG  . GLN B 2 242 ? 114.382 92.433  164.720 1.00 105.92 ? 243 GLN A CG  1 
ATOM 2462 C CD  . GLN B 2 242 ? 113.625 92.482  166.031 1.00 113.03 ? 243 GLN A CD  1 
ATOM 2463 O OE1 . GLN B 2 242 ? 113.491 91.471  166.721 1.00 113.09 ? 243 GLN A OE1 1 
ATOM 2464 N NE2 . GLN B 2 242 ? 113.119 93.659  166.378 1.00 114.61 ? 243 GLN A NE2 1 
ATOM 2465 N N   . ALA B 2 243 ? 115.613 88.748  161.870 1.00 94.47  ? 244 ALA A N   1 
ATOM 2466 C CA  . ALA B 2 243 ? 115.683 87.300  161.718 1.00 101.19 ? 244 ALA A CA  1 
ATOM 2467 C C   . ALA B 2 243 ? 117.118 86.792  161.678 1.00 105.27 ? 244 ALA A C   1 
ATOM 2468 O O   . ALA B 2 243 ? 117.391 85.682  162.148 1.00 111.29 ? 244 ALA A O   1 
ATOM 2469 C CB  . ALA B 2 243 ? 114.937 86.872  160.459 1.00 106.73 ? 244 ALA A CB  1 
ATOM 2470 N N   . ILE B 2 244 ? 118.048 87.586  161.140 1.00 96.94  ? 245 ILE A N   1 
ATOM 2471 C CA  . ILE B 2 244 ? 119.414 87.125  160.933 1.00 93.94  ? 245 ILE A CA  1 
ATOM 2472 C C   . ILE B 2 244 ? 120.113 86.760  162.232 1.00 94.65  ? 245 ILE A C   1 
ATOM 2473 O O   . ILE B 2 244 ? 121.240 86.262  162.201 1.00 103.30 ? 245 ILE A O   1 
ATOM 2474 C CB  . ILE B 2 244 ? 120.235 88.186  160.171 1.00 93.34  ? 245 ILE A CB  1 
ATOM 2475 C CG1 . ILE B 2 244 ? 120.523 89.387  161.070 1.00 96.19  ? 245 ILE A CG1 1 
ATOM 2476 C CG2 . ILE B 2 244 ? 119.510 88.621  158.914 1.00 98.89  ? 245 ILE A CG2 1 
ATOM 2477 C CD1 . ILE B 2 244 ? 121.749 90.167  160.662 1.00 92.81  ? 245 ILE A CD1 1 
ATOM 2478 N N   . LYS B 2 245 ? 119.472 86.997  163.375 1.00 97.68  ? 246 LYS A N   1 
ATOM 2479 C CA  . LYS B 2 245 ? 120.004 86.542  164.650 1.00 103.24 ? 246 LYS A CA  1 
ATOM 2480 C C   . LYS B 2 245 ? 119.974 85.027  164.792 1.00 105.71 ? 246 LYS A C   1 
ATOM 2481 O O   . LYS B 2 245 ? 120.577 84.500  165.732 1.00 109.38 ? 246 LYS A O   1 
ATOM 2482 C CB  . LYS B 2 245 ? 119.225 87.185  165.798 1.00 98.17  ? 246 LYS A CB  1 
ATOM 2483 C CG  . LYS B 2 245 ? 117.965 86.433  166.183 1.00 107.53 ? 246 LYS A CG  1 
ATOM 2484 C CD  . LYS B 2 245 ? 117.236 87.124  167.321 1.00 108.93 ? 246 LYS A CD  1 
ATOM 2485 C CE  . LYS B 2 245 ? 115.957 86.387  167.680 1.00 113.14 ? 246 LYS A CE  1 
ATOM 2486 N NZ  . LYS B 2 245 ? 115.992 84.967  167.232 1.00 111.36 ? 246 LYS A NZ  1 
ATOM 2487 N N   . ALA B 2 246 ? 119.294 84.315  163.892 1.00 87.89  ? 247 ALA A N   1 
ATOM 2488 C CA  . ALA B 2 246 ? 119.184 82.864  163.962 1.00 89.66  ? 247 ALA A CA  1 
ATOM 2489 C C   . ALA B 2 246 ? 120.030 82.168  162.899 1.00 94.11  ? 247 ALA A C   1 
ATOM 2490 O O   . ALA B 2 246 ? 119.661 81.100  162.407 1.00 95.67  ? 247 ALA A O   1 
ATOM 2491 C CB  . ALA B 2 246 ? 117.723 82.435  163.845 1.00 92.57  ? 247 ALA A CB  1 
ATOM 2492 N N   . LEU B 2 247 ? 121.169 82.759  162.539 1.00 96.43  ? 248 LEU A N   1 
ATOM 2493 C CA  . LEU B 2 247 ? 122.090 82.194  161.551 1.00 94.41  ? 248 LEU A CA  1 
ATOM 2494 C C   . LEU B 2 247 ? 123.482 82.147  162.165 1.00 89.56  ? 248 LEU A C   1 
ATOM 2495 O O   . LEU B 2 247 ? 124.321 83.019  161.903 1.00 88.71  ? 248 LEU A O   1 
ATOM 2496 C CB  . LEU B 2 247 ? 122.084 83.005  160.255 1.00 89.36  ? 248 LEU A CB  1 
ATOM 2497 C CG  . LEU B 2 247 ? 120.716 83.405  159.701 1.00 84.86  ? 248 LEU A CG  1 
ATOM 2498 C CD1 . LEU B 2 247 ? 120.871 84.326  158.507 1.00 91.87  ? 248 LEU A CD1 1 
ATOM 2499 C CD2 . LEU B 2 247 ? 119.924 82.171  159.322 1.00 83.98  ? 248 LEU A CD2 1 
ATOM 2500 N N   . PRO B 2 248 ? 123.763 81.136  162.992 1.00 81.56  ? 249 PRO A N   1 
ATOM 2501 C CA  . PRO B 2 248 ? 125.057 81.095  163.693 1.00 85.57  ? 249 PRO A CA  1 
ATOM 2502 C C   . PRO B 2 248 ? 126.259 80.943  162.777 1.00 90.57  ? 249 PRO A C   1 
ATOM 2503 O O   . PRO B 2 248 ? 127.369 81.304  163.186 1.00 91.28  ? 249 PRO A O   1 
ATOM 2504 C CB  . PRO B 2 248 ? 124.918 79.881  164.623 1.00 84.27  ? 249 PRO A CB  1 
ATOM 2505 C CG  . PRO B 2 248 ? 123.453 79.574  164.666 1.00 84.92  ? 249 PRO A CG  1 
ATOM 2506 C CD  . PRO B 2 248 ? 122.904 79.997  163.347 1.00 84.05  ? 249 PRO A CD  1 
ATOM 2507 N N   . SER B 2 249 ? 126.087 80.425  161.564 1.00 92.67  ? 250 SER A N   1 
ATOM 2508 C CA  . SER B 2 249 ? 127.204 80.144  160.673 1.00 91.19  ? 250 SER A CA  1 
ATOM 2509 C C   . SER B 2 249 ? 127.391 81.205  159.598 1.00 90.72  ? 250 SER A C   1 
ATOM 2510 O O   . SER B 2 249 ? 128.138 80.975  158.643 1.00 95.10  ? 250 SER A O   1 
ATOM 2511 C CB  . SER B 2 249 ? 127.024 78.773  160.018 1.00 94.66  ? 250 SER A CB  1 
ATOM 2512 O OG  . SER B 2 249 ? 127.421 77.733  160.893 1.00 99.50  ? 250 SER A OG  1 
ATOM 2513 N N   . LEU B 2 250 ? 126.727 82.351  159.724 1.00 78.68  ? 251 LEU A N   1 
ATOM 2514 C CA  . LEU B 2 250 ? 126.796 83.374  158.690 1.00 71.84  ? 251 LEU A CA  1 
ATOM 2515 C C   . LEU B 2 250 ? 128.225 83.873  158.518 1.00 76.22  ? 251 LEU A C   1 
ATOM 2516 O O   . LEU B 2 250 ? 128.918 84.159  159.497 1.00 89.54  ? 251 LEU A O   1 
ATOM 2517 C CB  . LEU B 2 250 ? 125.868 84.536  159.039 1.00 69.89  ? 251 LEU A CB  1 
ATOM 2518 C CG  . LEU B 2 250 ? 125.446 85.444  157.884 1.00 67.46  ? 251 LEU A CG  1 
ATOM 2519 C CD1 . LEU B 2 250 ? 125.008 84.619  156.689 1.00 80.71  ? 251 LEU A CD1 1 
ATOM 2520 C CD2 . LEU B 2 250 ? 124.338 86.381  158.322 1.00 72.21  ? 251 LEU A CD2 1 
ATOM 2521 N N   . LYS B 2 251 ? 128.664 83.967  157.267 1.00 83.30  ? 252 LYS A N   1 
ATOM 2522 C CA  . LYS B 2 251 ? 129.971 84.512  156.930 1.00 77.74  ? 252 LYS A CA  1 
ATOM 2523 C C   . LYS B 2 251 ? 129.908 85.691  155.977 1.00 80.03  ? 252 LYS A C   1 
ATOM 2524 O O   . LYS B 2 251 ? 130.759 86.577  156.061 1.00 87.22  ? 252 LYS A O   1 
ATOM 2525 C CB  . LYS B 2 251 ? 130.864 83.431  156.305 1.00 72.74  ? 252 LYS A CB  1 
ATOM 2526 C CG  . LYS B 2 251 ? 131.462 82.459  157.299 1.00 73.84  ? 252 LYS A CG  1 
ATOM 2527 C CD  . LYS B 2 251 ? 132.105 81.286  156.583 1.00 80.80  ? 252 LYS A CD  1 
ATOM 2528 C CE  . LYS B 2 251 ? 132.748 80.329  157.566 1.00 88.26  ? 252 LYS A CE  1 
ATOM 2529 N NZ  . LYS B 2 251 ? 131.740 79.726  158.479 1.00 86.74  ? 252 LYS A NZ  1 
ATOM 2530 N N   . GLU B 2 252 ? 128.934 85.723  155.074 1.00 88.24  ? 253 GLU A N   1 
ATOM 2531 C CA  . GLU B 2 252 ? 128.745 86.834  154.156 1.00 83.71  ? 253 GLU A CA  1 
ATOM 2532 C C   . GLU B 2 252 ? 127.298 87.290  154.235 1.00 88.28  ? 253 GLU A C   1 
ATOM 2533 O O   . GLU B 2 252 ? 126.380 86.475  154.098 1.00 100.78 ? 253 GLU A O   1 
ATOM 2534 C CB  . GLU B 2 252 ? 129.097 86.434  152.721 1.00 93.83  ? 253 GLU A CB  1 
ATOM 2535 C CG  . GLU B 2 252 ? 129.588 87.583  151.863 1.00 101.02 ? 253 GLU A CG  1 
ATOM 2536 C CD  . GLU B 2 252 ? 129.571 87.259  150.383 1.00 109.03 ? 253 GLU A CD  1 
ATOM 2537 O OE1 . GLU B 2 252 ? 129.190 86.126  150.025 1.00 112.03 ? 253 GLU A OE1 1 
ATOM 2538 O OE2 . GLU B 2 252 ? 129.940 88.138  149.577 1.00 108.86 ? 253 GLU A OE2 1 
ATOM 2539 N N   . LEU B 2 253 ? 127.096 88.584  154.458 1.00 69.90  ? 254 LEU A N   1 
ATOM 2540 C CA  . LEU B 2 253 ? 125.763 89.161  154.544 1.00 72.82  ? 254 LEU A CA  1 
ATOM 2541 C C   . LEU B 2 253 ? 125.719 90.424  153.703 1.00 75.96  ? 254 LEU A C   1 
ATOM 2542 O O   . LEU B 2 253 ? 126.601 91.280  153.818 1.00 83.80  ? 254 LEU A O   1 
ATOM 2543 C CB  . LEU B 2 253 ? 125.385 89.475  155.993 1.00 72.19  ? 254 LEU A CB  1 
ATOM 2544 C CG  . LEU B 2 253 ? 124.114 90.298  156.186 1.00 70.81  ? 254 LEU A CG  1 
ATOM 2545 C CD1 . LEU B 2 253 ? 122.892 89.460  155.874 1.00 75.09  ? 254 LEU A CD1 1 
ATOM 2546 C CD2 . LEU B 2 253 ? 124.042 90.840  157.598 1.00 73.49  ? 254 LEU A CD2 1 
ATOM 2547 N N   . GLY B 2 254 ? 124.699 90.538  152.861 1.00 74.46  ? 255 GLY A N   1 
ATOM 2548 C CA  . GLY B 2 254 ? 124.571 91.699  152.008 1.00 77.44  ? 255 GLY A CA  1 
ATOM 2549 C C   . GLY B 2 254 ? 123.174 92.278  151.988 1.00 80.63  ? 255 GLY A C   1 
ATOM 2550 O O   . GLY B 2 254 ? 122.209 91.580  151.666 1.00 91.00  ? 255 GLY A O   1 
ATOM 2551 N N   . PHE B 2 255 ? 123.050 93.560  152.333 1.00 69.46  ? 256 PHE A N   1 
ATOM 2552 C CA  . PHE B 2 255 ? 121.769 94.247  152.251 1.00 73.79  ? 256 PHE A CA  1 
ATOM 2553 C C   . PHE B 2 255 ? 121.932 95.661  151.709 1.00 78.64  ? 256 PHE A C   1 
ATOM 2554 O O   . PHE B 2 255 ? 121.174 96.563  152.081 1.00 82.04  ? 256 PHE A O   1 
ATOM 2555 C CB  . PHE B 2 255 ? 121.066 94.275  153.609 1.00 74.81  ? 256 PHE A CB  1 
ATOM 2556 C CG  . PHE B 2 255 ? 121.933 94.754  154.734 1.00 75.64  ? 256 PHE A CG  1 
ATOM 2557 C CD1 . PHE B 2 255 ? 122.003 96.099  155.048 1.00 78.54  ? 256 PHE A CD1 1 
ATOM 2558 C CD2 . PHE B 2 255 ? 122.669 93.859  155.487 1.00 83.77  ? 256 PHE A CD2 1 
ATOM 2559 C CE1 . PHE B 2 255 ? 122.794 96.542  156.085 1.00 75.60  ? 256 PHE A CE1 1 
ATOM 2560 C CE2 . PHE B 2 255 ? 123.464 94.297  156.524 1.00 87.05  ? 256 PHE A CE2 1 
ATOM 2561 C CZ  . PHE B 2 255 ? 123.526 95.640  156.823 1.00 81.75  ? 256 PHE A CZ  1 
ATOM 2562 N N   . HIS B 2 256 ? 122.908 95.871  150.831 1.00 82.45  ? 257 HIS A N   1 
ATOM 2563 C CA  . HIS B 2 256 ? 123.119 97.188  150.255 1.00 88.45  ? 257 HIS A CA  1 
ATOM 2564 C C   . HIS B 2 256 ? 122.001 97.531  149.275 1.00 87.70  ? 257 HIS A C   1 
ATOM 2565 O O   . HIS B 2 256 ? 121.287 96.660  148.774 1.00 88.19  ? 257 HIS A O   1 
ATOM 2566 C CB  . HIS B 2 256 ? 124.486 97.264  149.568 1.00 85.09  ? 257 HIS A CB  1 
ATOM 2567 C CG  . HIS B 2 256 ? 124.577 96.487  148.292 1.00 86.90  ? 257 HIS A CG  1 
ATOM 2568 N ND1 . HIS B 2 256 ? 124.016 96.921  147.110 1.00 91.14  ? 257 HIS A ND1 1 
ATOM 2569 C CD2 . HIS B 2 256 ? 125.187 95.313  148.007 1.00 88.43  ? 257 HIS A CD2 1 
ATOM 2570 C CE1 . HIS B 2 256 ? 124.264 96.041  146.157 1.00 90.64  ? 257 HIS A CE1 1 
ATOM 2571 N NE2 . HIS B 2 256 ? 124.973 95.055  146.675 1.00 91.35  ? 257 HIS A NE2 1 
ATOM 2572 N N   . SER B 2 257 ? 121.848 98.832  149.022 1.00 92.48  ? 258 SER A N   1 
ATOM 2573 C CA  . SER B 2 257 ? 120.822 99.359  148.119 1.00 86.87  ? 258 SER A CA  1 
ATOM 2574 C C   . SER B 2 257 ? 119.418 99.035  148.628 1.00 87.87  ? 258 SER A C   1 
ATOM 2575 O O   . SER B 2 257 ? 118.564 98.535  147.894 1.00 94.44  ? 258 SER A O   1 
ATOM 2576 C CB  . SER B 2 257 ? 121.022 98.845  146.692 1.00 90.09  ? 258 SER A CB  1 
ATOM 2577 O OG  . SER B 2 257 ? 122.101 99.506  146.056 1.00 96.22  ? 258 SER A OG  1 
ATOM 2578 N N   . ASN B 2 258 ? 119.183 99.331  149.898 1.00 83.94  ? 259 ASN A N   1 
ATOM 2579 C CA  . ASN B 2 258 ? 117.885 99.160  150.533 1.00 80.93  ? 259 ASN A CA  1 
ATOM 2580 C C   . ASN B 2 258 ? 117.388 100.517 151.024 1.00 89.30  ? 259 ASN A C   1 
ATOM 2581 O O   . ASN B 2 258 ? 117.995 101.558 150.764 1.00 93.15  ? 259 ASN A O   1 
ATOM 2582 C CB  . ASN B 2 258 ? 117.974 98.148  151.675 1.00 79.05  ? 259 ASN A CB  1 
ATOM 2583 C CG  . ASN B 2 258 ? 117.820 96.725  151.200 1.00 88.97  ? 259 ASN A CG  1 
ATOM 2584 O OD1 . ASN B 2 258 ? 117.931 96.442  150.009 1.00 94.52  ? 259 ASN A OD1 1 
ATOM 2585 N ND2 . ASN B 2 258 ? 117.561 95.815  152.131 1.00 92.45  ? 259 ASN A ND2 1 
ATOM 2586 N N   . SER B 2 259 ? 116.304 100.517 151.783 1.00 96.82  ? 260 SER A N   1 
ATOM 2587 C CA  . SER B 2 259 ? 115.778 101.769 152.360 1.00 97.63  ? 260 SER A CA  1 
ATOM 2588 C C   . SER B 2 259 ? 116.202 101.876 153.821 1.00 100.04 ? 260 SER A C   1 
ATOM 2589 O O   . SER B 2 259 ? 116.015 102.948 154.402 1.00 101.22 ? 260 SER A O   1 
ATOM 2590 C CB  . SER B 2 259 ? 114.314 101.774 152.220 1.00 100.49 ? 260 SER A CB  1 
ATOM 2591 O OG  . SER B 2 259 ? 113.653 101.998 153.455 1.00 105.28 ? 260 SER A OG  1 
ATOM 2592 N N   . ILE B 2 260 ? 116.880 100.882 154.361 1.00 96.87  ? 261 ILE A N   1 
ATOM 2593 C CA  . ILE B 2 260 ? 117.171 100.836 155.787 1.00 85.76  ? 261 ILE A CA  1 
ATOM 2594 C C   . ILE B 2 260 ? 117.894 102.110 156.201 1.00 81.29  ? 261 ILE A C   1 
ATOM 2595 O O   . ILE B 2 260 ? 118.705 102.661 155.446 1.00 87.45  ? 261 ILE A O   1 
ATOM 2596 C CB  . ILE B 2 260 ? 117.997 99.582  156.119 1.00 81.63  ? 261 ILE A CB  1 
ATOM 2597 C CG1 . ILE B 2 260 ? 118.312 99.517  157.612 1.00 85.61  ? 261 ILE A CG1 1 
ATOM 2598 C CG2 . ILE B 2 260 ? 119.272 99.555  155.305 1.00 81.55  ? 261 ILE A CG2 1 
ATOM 2599 C CD1 . ILE B 2 260 ? 117.082 99.452  158.477 1.00 94.29  ? 261 ILE A CD1 1 
ATOM 2600 N N   . SER B 2 261 ? 117.590 102.594 157.406 1.00 92.33  ? 262 SER A N   1 
ATOM 2601 C CA  . SER B 2 261 ? 118.181 103.833 157.896 1.00 100.13 ? 262 SER A CA  1 
ATOM 2602 C C   . SER B 2 261 ? 118.804 103.657 159.275 1.00 95.84  ? 262 SER A C   1 
ATOM 2603 O O   . SER B 2 261 ? 119.766 104.351 159.619 1.00 96.34  ? 262 SER A O   1 
ATOM 2604 C CB  . SER B 2 261 ? 117.128 104.942 157.935 1.00 95.13  ? 262 SER A CB  1 
ATOM 2605 O OG  . SER B 2 261 ? 116.238 104.758 159.022 1.00 93.18  ? 262 SER A OG  1 
ATOM 2606 N N   . VAL B 2 262 ? 118.267 102.737 160.070 1.00 87.91  ? 263 VAL A N   1 
ATOM 2607 C CA  . VAL B 2 262 ? 118.703 102.528 161.445 1.00 87.07  ? 263 VAL A CA  1 
ATOM 2608 C C   . VAL B 2 262 ? 119.215 101.102 161.574 1.00 97.13  ? 263 VAL A C   1 
ATOM 2609 O O   . VAL B 2 262 ? 118.486 100.147 161.283 1.00 109.35 ? 263 VAL A O   1 
ATOM 2610 C CB  . VAL B 2 262 ? 117.568 102.790 162.447 1.00 88.95  ? 263 VAL A CB  1 
ATOM 2611 C CG1 . VAL B 2 262 ? 117.919 102.216 163.810 1.00 85.70  ? 263 VAL A CG1 1 
ATOM 2612 C CG2 . VAL B 2 262 ? 117.280 104.276 162.544 1.00 91.88  ? 263 VAL A CG2 1 
ATOM 2613 N N   . ILE B 2 263 ? 120.459 100.958 162.016 1.00 89.89  ? 264 ILE A N   1 
ATOM 2614 C CA  . ILE B 2 263 ? 121.054 99.664  162.330 1.00 82.72  ? 264 ILE A CA  1 
ATOM 2615 C C   . ILE B 2 263 ? 121.272 99.619  163.840 1.00 81.31  ? 264 ILE A C   1 
ATOM 2616 O O   . ILE B 2 263 ? 122.217 100.240 164.347 1.00 96.63  ? 264 ILE A O   1 
ATOM 2617 C CB  . ILE B 2 263 ? 122.366 99.437  161.570 1.00 82.55  ? 264 ILE A CB  1 
ATOM 2618 C CG1 . ILE B 2 263 ? 122.120 99.463  160.062 1.00 86.48  ? 264 ILE A CG1 1 
ATOM 2619 C CG2 . ILE B 2 263 ? 122.988 98.114  161.977 1.00 84.97  ? 264 ILE A CG2 1 
ATOM 2620 C CD1 . ILE B 2 263 ? 123.298 98.986  159.245 1.00 85.18  ? 264 ILE A CD1 1 
ATOM 2621 N N   . PRO B 2 264 ? 120.443 98.907  164.593 1.00 80.34  ? 265 PRO A N   1 
ATOM 2622 C CA  . PRO B 2 264 ? 120.498 98.993  166.052 1.00 92.22  ? 265 PRO A CA  1 
ATOM 2623 C C   . PRO B 2 264 ? 121.570 98.084  166.639 1.00 97.70  ? 265 PRO A C   1 
ATOM 2624 O O   . PRO B 2 264 ? 122.130 97.214  165.973 1.00 99.49  ? 265 PRO A O   1 
ATOM 2625 C CB  . PRO B 2 264 ? 119.098 98.545  166.480 1.00 89.57  ? 265 PRO A CB  1 
ATOM 2626 C CG  . PRO B 2 264 ? 118.609 97.671  165.356 1.00 93.57  ? 265 PRO A CG  1 
ATOM 2627 C CD  . PRO B 2 264 ? 119.464 97.909  164.135 1.00 90.71  ? 265 PRO A CD  1 
ATOM 2628 N N   . ASP B 2 265 ? 121.846 98.311  167.921 1.00 99.27  ? 266 ASP A N   1 
ATOM 2629 C CA  . ASP B 2 265 ? 122.780 97.470  168.655 1.00 95.16  ? 266 ASP A CA  1 
ATOM 2630 C C   . ASP B 2 265 ? 122.260 96.040  168.726 1.00 100.89 ? 266 ASP A C   1 
ATOM 2631 O O   . ASP B 2 265 ? 121.052 95.795  168.773 1.00 103.85 ? 266 ASP A O   1 
ATOM 2632 C CB  . ASP B 2 265 ? 122.997 98.018  170.064 1.00 100.58 ? 266 ASP A CB  1 
ATOM 2633 C CG  . ASP B 2 265 ? 124.109 99.040  170.126 1.00 106.47 ? 266 ASP A CG  1 
ATOM 2634 O OD1 . ASP B 2 265 ? 124.734 99.298  169.078 1.00 107.73 ? 266 ASP A OD1 1 
ATOM 2635 O OD2 . ASP B 2 265 ? 124.358 99.586  171.220 1.00 106.82 ? 266 ASP A OD2 1 
ATOM 2636 N N   . GLY B 2 266 ? 123.188 95.088  168.736 1.00 96.33  ? 267 GLY A N   1 
ATOM 2637 C CA  . GLY B 2 266 ? 122.811 93.692  168.692 1.00 96.29  ? 267 GLY A CA  1 
ATOM 2638 C C   . GLY B 2 266 ? 122.341 93.220  167.338 1.00 97.61  ? 267 GLY A C   1 
ATOM 2639 O O   . GLY B 2 266 ? 121.666 92.191  167.252 1.00 100.48 ? 267 GLY A O   1 
ATOM 2640 N N   . ALA B 2 267 ? 122.665 93.956  166.274 1.00 84.63  ? 268 ALA A N   1 
ATOM 2641 C CA  . ALA B 2 267 ? 122.256 93.550  164.936 1.00 74.66  ? 268 ALA A CA  1 
ATOM 2642 C C   . ALA B 2 267 ? 122.900 92.231  164.535 1.00 80.16  ? 268 ALA A C   1 
ATOM 2643 O O   . ALA B 2 267 ? 122.251 91.379  163.918 1.00 84.14  ? 268 ALA A O   1 
ATOM 2644 C CB  . ALA B 2 267 ? 122.605 94.644  163.930 1.00 75.73  ? 268 ALA A CB  1 
ATOM 2645 N N   . PHE B 2 268 ? 124.176 92.042  164.875 1.00 87.00  ? 269 PHE A N   1 
ATOM 2646 C CA  . PHE B 2 268 ? 124.929 90.863  164.462 1.00 90.18  ? 269 PHE A CA  1 
ATOM 2647 C C   . PHE B 2 268 ? 125.345 89.997  165.645 1.00 89.80  ? 269 PHE A C   1 
ATOM 2648 O O   . PHE B 2 268 ? 126.280 89.200  165.523 1.00 97.26  ? 269 PHE A O   1 
ATOM 2649 C CB  . PHE B 2 268 ? 126.162 91.276  163.658 1.00 90.78  ? 269 PHE A CB  1 
ATOM 2650 C CG  . PHE B 2 268 ? 125.873 92.265  162.570 1.00 86.53  ? 269 PHE A CG  1 
ATOM 2651 C CD1 . PHE B 2 268 ? 125.147 91.895  161.454 1.00 82.30  ? 269 PHE A CD1 1 
ATOM 2652 C CD2 . PHE B 2 268 ? 126.330 93.566  162.663 1.00 88.12  ? 269 PHE A CD2 1 
ATOM 2653 C CE1 . PHE B 2 268 ? 124.882 92.805  160.453 1.00 83.54  ? 269 PHE A CE1 1 
ATOM 2654 C CE2 . PHE B 2 268 ? 126.067 94.479  161.666 1.00 83.83  ? 269 PHE A CE2 1 
ATOM 2655 C CZ  . PHE B 2 268 ? 125.342 94.098  160.559 1.00 84.19  ? 269 PHE A CZ  1 
ATOM 2656 N N   . ASP B 2 269 ? 124.675 90.137  166.790 1.00 100.08 ? 270 ASP A N   1 
ATOM 2657 C CA  . ASP B 2 269 ? 125.095 89.405  167.980 1.00 105.06 ? 270 ASP A CA  1 
ATOM 2658 C C   . ASP B 2 269 ? 124.933 87.900  167.812 1.00 103.75 ? 270 ASP A C   1 
ATOM 2659 O O   . ASP B 2 269 ? 125.711 87.129  168.384 1.00 106.91 ? 270 ASP A O   1 
ATOM 2660 C CB  . ASP B 2 269 ? 124.311 89.892  169.198 1.00 103.93 ? 270 ASP A CB  1 
ATOM 2661 C CG  . ASP B 2 269 ? 122.820 89.946  168.947 1.00 113.27 ? 270 ASP A CG  1 
ATOM 2662 O OD1 . ASP B 2 269 ? 122.383 89.517  167.859 1.00 119.56 ? 270 ASP A OD1 1 
ATOM 2663 O OD2 . ASP B 2 269 ? 122.083 90.421  169.836 1.00 111.56 ? 270 ASP A OD2 1 
ATOM 2664 N N   . GLY B 2 270 ? 123.943 87.463  167.036 1.00 86.24  ? 271 GLY A N   1 
ATOM 2665 C CA  . GLY B 2 270 ? 123.703 86.043  166.873 1.00 87.96  ? 271 GLY A CA  1 
ATOM 2666 C C   . GLY B 2 270 ? 124.553 85.353  165.830 1.00 92.94  ? 271 GLY A C   1 
ATOM 2667 O O   . GLY B 2 270 ? 124.484 84.126  165.712 1.00 101.20 ? 271 GLY A O   1 
ATOM 2668 N N   . ASN B 2 271 ? 125.353 86.103  165.075 1.00 89.84  ? 272 ASN A N   1 
ATOM 2669 C CA  . ASN B 2 271 ? 126.170 85.560  163.990 1.00 93.56  ? 272 ASN A CA  1 
ATOM 2670 C C   . ASN B 2 271 ? 127.599 86.067  164.137 1.00 90.02  ? 272 ASN A C   1 
ATOM 2671 O O   . ASN B 2 271 ? 127.995 87.047  163.492 1.00 86.10  ? 272 ASN A O   1 
ATOM 2672 C CB  . ASN B 2 271 ? 125.577 85.926  162.631 1.00 86.53  ? 272 ASN A CB  1 
ATOM 2673 C CG  . ASN B 2 271 ? 125.058 87.344  162.590 1.00 86.97  ? 272 ASN A CG  1 
ATOM 2674 O OD1 . ASN B 2 271 ? 124.132 87.697  163.319 1.00 85.12  ? 272 ASN A OD1 1 
ATOM 2675 N ND2 . ASN B 2 271 ? 125.648 88.166  161.735 1.00 92.64  ? 272 ASN A ND2 1 
ATOM 2676 N N   . PRO B 2 272 ? 128.406 85.415  164.975 1.00 80.04  ? 273 PRO A N   1 
ATOM 2677 C CA  . PRO B 2 272 ? 129.760 85.902  165.255 1.00 83.55  ? 273 PRO A CA  1 
ATOM 2678 C C   . PRO B 2 272 ? 130.814 85.494  164.237 1.00 87.88  ? 273 PRO A C   1 
ATOM 2679 O O   . PRO B 2 272 ? 131.996 85.764  164.466 1.00 92.76  ? 273 PRO A O   1 
ATOM 2680 C CB  . PRO B 2 272 ? 130.057 85.264  166.618 1.00 87.66  ? 273 PRO A CB  1 
ATOM 2681 C CG  . PRO B 2 272 ? 129.335 83.967  166.562 1.00 82.29  ? 273 PRO A CG  1 
ATOM 2682 C CD  . PRO B 2 272 ? 128.081 84.211  165.759 1.00 78.93  ? 273 PRO A CD  1 
ATOM 2683 N N   . LEU B 2 273 ? 130.440 84.852  163.132 1.00 81.63  ? 274 LEU A N   1 
ATOM 2684 C CA  . LEU B 2 273 ? 131.396 84.410  162.125 1.00 77.51  ? 274 LEU A CA  1 
ATOM 2685 C C   . LEU B 2 273 ? 131.406 85.308  160.895 1.00 75.18  ? 274 LEU A C   1 
ATOM 2686 O O   . LEU B 2 273 ? 131.930 84.909  159.850 1.00 78.48  ? 274 LEU A O   1 
ATOM 2687 C CB  . LEU B 2 273 ? 131.106 82.966  161.717 1.00 78.86  ? 274 LEU A CB  1 
ATOM 2688 C CG  . LEU B 2 273 ? 131.714 81.864  162.585 1.00 80.81  ? 274 LEU A CG  1 
ATOM 2689 C CD1 . LEU B 2 273 ? 130.869 81.623  163.824 1.00 89.51  ? 274 LEU A CD1 1 
ATOM 2690 C CD2 . LEU B 2 273 ? 131.868 80.584  161.784 1.00 77.25  ? 274 LEU A CD2 1 
ATOM 2691 N N   . LEU B 2 274 ? 130.835 86.504  160.995 1.00 77.90  ? 275 LEU A N   1 
ATOM 2692 C CA  . LEU B 2 274 ? 130.737 87.388  159.844 1.00 81.33  ? 275 LEU A CA  1 
ATOM 2693 C C   . LEU B 2 274 ? 132.117 87.816  159.366 1.00 81.65  ? 275 LEU A C   1 
ATOM 2694 O O   . LEU B 2 274 ? 133.024 88.056  160.167 1.00 87.75  ? 275 LEU A O   1 
ATOM 2695 C CB  . LEU B 2 274 ? 129.902 88.618  160.191 1.00 77.98  ? 275 LEU A CB  1 
ATOM 2696 C CG  . LEU B 2 274 ? 128.481 88.623  159.632 1.00 77.60  ? 275 LEU A CG  1 
ATOM 2697 C CD1 . LEU B 2 274 ? 127.777 89.914  159.991 1.00 81.38  ? 275 LEU A CD1 1 
ATOM 2698 C CD2 . LEU B 2 274 ? 128.501 88.422  158.129 1.00 86.66  ? 275 LEU A CD2 1 
ATOM 2699 N N   . ARG B 2 275 ? 132.274 87.905  158.051 1.00 89.09  ? 276 ARG A N   1 
ATOM 2700 C CA  . ARG B 2 275 ? 133.521 88.342  157.440 1.00 87.32  ? 276 ARG A CA  1 
ATOM 2701 C C   . ARG B 2 275 ? 133.371 89.600  156.605 1.00 88.67  ? 276 ARG A C   1 
ATOM 2702 O O   . ARG B 2 275 ? 134.234 90.477  156.664 1.00 99.43  ? 276 ARG A O   1 
ATOM 2703 C CB  . ARG B 2 275 ? 134.106 87.221  156.571 1.00 90.20  ? 276 ARG A CB  1 
ATOM 2704 C CG  . ARG B 2 275 ? 134.987 86.252  157.338 1.00 96.04  ? 276 ARG A CG  1 
ATOM 2705 C CD  . ARG B 2 275 ? 136.210 85.862  156.530 1.00 95.92  ? 276 ARG A CD  1 
ATOM 2706 N NE  . ARG B 2 275 ? 135.848 85.200  155.283 1.00 105.73 ? 276 ARG A NE  1 
ATOM 2707 C CZ  . ARG B 2 275 ? 135.604 83.902  155.170 1.00 106.84 ? 276 ARG A CZ  1 
ATOM 2708 N NH1 . ARG B 2 275 ? 135.672 83.092  156.213 1.00 101.34 ? 276 ARG A NH1 1 
ATOM 2709 N NH2 . ARG B 2 275 ? 135.283 83.404  153.979 1.00 102.25 ? 276 ARG A NH2 1 
ATOM 2710 N N   . THR B 2 276 ? 132.306 89.710  155.813 1.00 88.11  ? 277 THR A N   1 
ATOM 2711 C CA  . THR B 2 276 ? 132.028 90.910  155.037 1.00 97.94  ? 277 THR A CA  1 
ATOM 2712 C C   . THR B 2 276 ? 130.567 91.296  155.207 1.00 94.81  ? 277 THR A C   1 
ATOM 2713 O O   . THR B 2 276 ? 129.689 90.430  155.263 1.00 98.72  ? 277 THR A O   1 
ATOM 2714 C CB  . THR B 2 276 ? 132.328 90.719  153.542 1.00 101.30 ? 277 THR A CB  1 
ATOM 2715 O OG1 . THR B 2 276 ? 131.224 90.061  152.913 1.00 99.65  ? 277 THR A OG1 1 
ATOM 2716 C CG2 . THR B 2 276 ? 133.587 89.891  153.333 1.00 93.73  ? 277 THR A CG2 1 
ATOM 2717 N N   . ILE B 2 277 ? 130.312 92.599  155.293 1.00 73.97  ? 278 ILE A N   1 
ATOM 2718 C CA  . ILE B 2 277 ? 128.961 93.142  155.342 1.00 67.49  ? 278 ILE A CA  1 
ATOM 2719 C C   . ILE B 2 277 ? 128.860 94.248  154.305 1.00 78.00  ? 278 ILE A C   1 
ATOM 2720 O O   . ILE B 2 277 ? 129.687 95.167  154.290 1.00 87.49  ? 278 ILE A O   1 
ATOM 2721 C CB  . ILE B 2 277 ? 128.603 93.685  156.738 1.00 67.17  ? 278 ILE A CB  1 
ATOM 2722 C CG1 . ILE B 2 277 ? 128.756 92.593  157.794 1.00 72.41  ? 278 ILE A CG1 1 
ATOM 2723 C CG2 . ILE B 2 277 ? 127.189 94.226  156.750 1.00 76.85  ? 278 ILE A CG2 1 
ATOM 2724 C CD1 . ILE B 2 277 ? 129.445 93.063  159.049 1.00 82.11  ? 278 ILE A CD1 1 
ATOM 2725 N N   . HIS B 2 278 ? 127.853 94.164  153.443 1.00 81.70  ? 279 HIS A N   1 
ATOM 2726 C CA  . HIS B 2 278 ? 127.617 95.158  152.406 1.00 86.06  ? 279 HIS A CA  1 
ATOM 2727 C C   . HIS B 2 278 ? 126.410 95.996  152.800 1.00 85.48  ? 279 HIS A C   1 
ATOM 2728 O O   . HIS B 2 278 ? 125.291 95.478  152.877 1.00 91.66  ? 279 HIS A O   1 
ATOM 2729 C CB  . HIS B 2 278 ? 127.393 94.491  151.050 1.00 86.00  ? 279 HIS A CB  1 
ATOM 2730 C CG  . HIS B 2 278 ? 128.554 93.670  150.585 1.00 86.94  ? 279 HIS A CG  1 
ATOM 2731 N ND1 . HIS B 2 278 ? 128.403 92.431  150.003 1.00 91.73  ? 279 HIS A ND1 1 
ATOM 2732 C CD2 . HIS B 2 278 ? 129.885 93.912  150.617 1.00 87.63  ? 279 HIS A CD2 1 
ATOM 2733 C CE1 . HIS B 2 278 ? 129.591 91.944  149.696 1.00 90.32  ? 279 HIS A CE1 1 
ATOM 2734 N NE2 . HIS B 2 278 ? 130.508 92.823  150.057 1.00 90.84  ? 279 HIS A NE2 1 
ATOM 2735 N N   . LEU B 2 279 ? 126.638 97.287  153.050 1.00 70.56  ? 280 LEU A N   1 
ATOM 2736 C CA  . LEU B 2 279 ? 125.553 98.167  153.465 1.00 75.73  ? 280 LEU A CA  1 
ATOM 2737 C C   . LEU B 2 279 ? 125.612 99.527  152.778 1.00 79.19  ? 280 LEU A C   1 
ATOM 2738 O O   . LEU B 2 279 ? 124.997 100.482 153.266 1.00 87.10  ? 280 LEU A O   1 
ATOM 2739 C CB  . LEU B 2 279 ? 125.560 98.358  154.983 1.00 69.38  ? 280 LEU A CB  1 
ATOM 2740 C CG  . LEU B 2 279 ? 126.827 98.935  155.611 1.00 69.42  ? 280 LEU A CG  1 
ATOM 2741 C CD1 . LEU B 2 279 ? 126.462 99.919  156.702 1.00 78.83  ? 280 LEU A CD1 1 
ATOM 2742 C CD2 . LEU B 2 279 ? 127.699 97.831  156.169 1.00 80.09  ? 280 LEU A CD2 1 
ATOM 2743 N N   . TYR B 2 280 ? 126.329 99.643  151.664 1.00 89.60  ? 281 TYR A N   1 
ATOM 2744 C CA  . TYR B 2 280 ? 126.402 100.909 150.953 1.00 95.41  ? 281 TYR A CA  1 
ATOM 2745 C C   . TYR B 2 280 ? 125.093 101.167 150.208 1.00 94.31  ? 281 TYR A C   1 
ATOM 2746 O O   . TYR B 2 280 ? 124.169 100.349 150.211 1.00 96.71  ? 281 TYR A O   1 
ATOM 2747 C CB  . TYR B 2 280 ? 127.593 100.915 149.999 1.00 94.27  ? 281 TYR A CB  1 
ATOM 2748 C CG  . TYR B 2 280 ? 127.578 99.804  148.975 1.00 92.16  ? 281 TYR A CG  1 
ATOM 2749 C CD1 . TYR B 2 280 ? 126.952 99.973  147.748 1.00 93.36  ? 281 TYR A CD1 1 
ATOM 2750 C CD2 . TYR B 2 280 ? 128.200 98.590  149.230 1.00 91.06  ? 281 TYR A CD2 1 
ATOM 2751 C CE1 . TYR B 2 280 ? 126.938 98.964  146.810 1.00 95.66  ? 281 TYR A CE1 1 
ATOM 2752 C CE2 . TYR B 2 280 ? 128.192 97.576  148.296 1.00 96.94  ? 281 TYR A CE2 1 
ATOM 2753 C CZ  . TYR B 2 280 ? 127.559 97.768  147.088 1.00 100.25 ? 281 TYR A CZ  1 
ATOM 2754 O OH  . TYR B 2 280 ? 127.548 96.761  146.153 1.00 102.69 ? 281 TYR A OH  1 
ATOM 2755 N N   . ASP B 2 281 ? 125.013 102.336 149.573 1.00 98.55  ? 282 ASP A N   1 
ATOM 2756 C CA  . ASP B 2 281 ? 123.840 102.768 148.814 1.00 95.17  ? 282 ASP A CA  1 
ATOM 2757 C C   . ASP B 2 281 ? 122.575 102.786 149.663 1.00 93.98  ? 282 ASP A C   1 
ATOM 2758 O O   . ASP B 2 281 ? 121.463 102.808 149.128 1.00 95.83  ? 282 ASP A O   1 
ATOM 2759 C CB  . ASP B 2 281 ? 123.626 101.895 147.573 1.00 98.13  ? 282 ASP A CB  1 
ATOM 2760 C CG  . ASP B 2 281 ? 124.344 102.431 146.354 1.00 107.54 ? 282 ASP A CG  1 
ATOM 2761 O OD1 . ASP B 2 281 ? 125.009 103.482 146.470 1.00 111.43 ? 282 ASP A OD1 1 
ATOM 2762 O OD2 . ASP B 2 281 ? 124.245 101.803 145.280 1.00 106.60 ? 282 ASP A OD2 1 
ATOM 2763 N N   . ASN B 2 282 ? 122.727 102.778 150.982 1.00 90.83  ? 283 ASN A N   1 
ATOM 2764 C CA  . ASN B 2 282 ? 121.612 102.790 151.906 1.00 95.04  ? 283 ASN A CA  1 
ATOM 2765 C C   . ASN B 2 282 ? 121.544 104.137 152.599 1.00 99.11  ? 283 ASN A C   1 
ATOM 2766 O O   . ASN B 2 282 ? 122.552 104.581 153.165 1.00 95.87  ? 283 ASN A O   1 
ATOM 2767 C CB  . ASN B 2 282 ? 121.764 101.681 152.949 1.00 83.73  ? 283 ASN A CB  1 
ATOM 2768 C CG  . ASN B 2 282 ? 121.380 100.325 152.412 1.00 91.77  ? 283 ASN A CG  1 
ATOM 2769 O OD1 . ASN B 2 282 ? 120.814 100.215 151.327 1.00 101.84 ? 283 ASN A OD1 1 
ATOM 2770 N ND2 . ASN B 2 282 ? 121.697 99.279  153.163 1.00 94.55  ? 283 ASN A ND2 1 
ATOM 2771 N N   . PRO B 2 283 ? 120.409 104.818 152.576 1.00 103.28 ? 284 PRO A N   1 
ATOM 2772 C CA  . PRO B 2 283 ? 120.311 106.071 153.330 1.00 97.37  ? 284 PRO A CA  1 
ATOM 2773 C C   . PRO B 2 283 ? 120.234 105.793 154.820 1.00 94.66  ? 284 PRO A C   1 
ATOM 2774 O O   . PRO B 2 283 ? 119.183 105.398 155.331 1.00 101.28 ? 284 PRO A O   1 
ATOM 2775 C CB  . PRO B 2 283 ? 119.021 106.703 152.798 1.00 101.32 ? 284 PRO A CB  1 
ATOM 2776 C CG  . PRO B 2 283 ? 118.197 105.545 152.343 1.00 97.62  ? 284 PRO A CG  1 
ATOM 2777 C CD  . PRO B 2 283 ? 119.148 104.465 151.901 1.00 100.75 ? 284 PRO A CD  1 
ATOM 2778 N N   . LEU B 2 284 ? 121.336 106.014 155.528 1.00 76.82  ? 285 LEU A N   1 
ATOM 2779 C CA  . LEU B 2 284 ? 121.424 105.726 156.950 1.00 80.24  ? 285 LEU A CA  1 
ATOM 2780 C C   . LEU B 2 284 ? 121.494 107.024 157.735 1.00 87.81  ? 285 LEU A C   1 
ATOM 2781 O O   . LEU B 2 284 ? 122.117 107.994 157.295 1.00 99.32  ? 285 LEU A O   1 
ATOM 2782 C CB  . LEU B 2 284 ? 122.649 104.867 157.274 1.00 83.56  ? 285 LEU A CB  1 
ATOM 2783 C CG  . LEU B 2 284 ? 122.621 103.392 156.877 1.00 84.18  ? 285 LEU A CG  1 
ATOM 2784 C CD1 . LEU B 2 284 ? 123.636 103.111 155.786 1.00 86.58  ? 285 LEU A CD1 1 
ATOM 2785 C CD2 . LEU B 2 284 ? 122.883 102.517 158.086 1.00 82.78  ? 285 LEU A CD2 1 
ATOM 2786 N N   . SER B 2 285 ? 120.842 107.041 158.894 1.00 93.06  ? 286 SER A N   1 
ATOM 2787 C CA  . SER B 2 285 ? 120.941 108.158 159.820 1.00 97.40  ? 286 SER A CA  1 
ATOM 2788 C C   . SER B 2 285 ? 121.740 107.781 161.059 1.00 96.83  ? 286 SER A C   1 
ATOM 2789 O O   . SER B 2 285 ? 122.727 108.443 161.389 1.00 101.23 ? 286 SER A O   1 
ATOM 2790 C CB  . SER B 2 285 ? 119.541 108.651 160.210 1.00 100.58 ? 286 SER A CB  1 
ATOM 2791 O OG  . SER B 2 285 ? 119.043 107.944 161.332 1.00 101.49 ? 286 SER A OG  1 
ATOM 2792 N N   . PHE B 2 286 ? 121.355 106.705 161.738 1.00 87.70  ? 287 PHE A N   1 
ATOM 2793 C CA  . PHE B 2 286 ? 121.971 106.307 162.993 1.00 83.93  ? 287 PHE A CA  1 
ATOM 2794 C C   . PHE B 2 286 ? 122.397 104.850 162.923 1.00 90.99  ? 287 PHE A C   1 
ATOM 2795 O O   . PHE B 2 286 ? 121.656 103.999 162.423 1.00 99.87  ? 287 PHE A O   1 
ATOM 2796 C CB  . PHE B 2 286 ? 121.007 106.517 164.165 1.00 84.08  ? 287 PHE A CB  1 
ATOM 2797 C CG  . PHE B 2 286 ? 121.395 105.778 165.411 1.00 85.92  ? 287 PHE A CG  1 
ATOM 2798 C CD1 . PHE B 2 286 ? 122.401 106.256 166.229 1.00 88.68  ? 287 PHE A CD1 1 
ATOM 2799 C CD2 . PHE B 2 286 ? 120.743 104.611 165.771 1.00 90.35  ? 287 PHE A CD2 1 
ATOM 2800 C CE1 . PHE B 2 286 ? 122.757 105.579 167.379 1.00 96.21  ? 287 PHE A CE1 1 
ATOM 2801 C CE2 . PHE B 2 286 ? 121.094 103.931 166.919 1.00 92.27  ? 287 PHE A CE2 1 
ATOM 2802 C CZ  . PHE B 2 286 ? 122.102 104.416 167.724 1.00 95.83  ? 287 PHE A CZ  1 
ATOM 2803 N N   . VAL B 2 287 ? 123.596 104.574 163.424 1.00 86.76  ? 288 VAL A N   1 
ATOM 2804 C CA  . VAL B 2 287 ? 124.122 103.221 163.553 1.00 79.25  ? 288 VAL A CA  1 
ATOM 2805 C C   . VAL B 2 287 ? 124.520 103.023 165.007 1.00 81.24  ? 288 VAL A C   1 
ATOM 2806 O O   . VAL B 2 287 ? 125.204 103.876 165.585 1.00 93.33  ? 288 VAL A O   1 
ATOM 2807 C CB  . VAL B 2 287 ? 125.320 102.982 162.615 1.00 78.67  ? 288 VAL A CB  1 
ATOM 2808 C CG1 . VAL B 2 287 ? 126.081 101.737 163.030 1.00 84.38  ? 288 VAL A CG1 1 
ATOM 2809 C CG2 . VAL B 2 287 ? 124.851 102.864 161.179 1.00 83.50  ? 288 VAL A CG2 1 
ATOM 2810 N N   . GLY B 2 288 ? 124.086 101.911 165.595 1.00 78.53  ? 289 GLY A N   1 
ATOM 2811 C CA  . GLY B 2 288 ? 124.343 101.685 167.004 1.00 79.08  ? 289 GLY A CA  1 
ATOM 2812 C C   . GLY B 2 288 ? 125.826 101.684 167.322 1.00 89.41  ? 289 GLY A C   1 
ATOM 2813 O O   . GLY B 2 288 ? 126.662 101.288 166.510 1.00 94.21  ? 289 GLY A O   1 
ATOM 2814 N N   . ASN B 2 289 ? 126.151 102.150 168.530 1.00 93.46  ? 290 ASN A N   1 
ATOM 2815 C CA  . ASN B 2 289 ? 127.550 102.228 168.934 1.00 91.12  ? 290 ASN A CA  1 
ATOM 2816 C C   . ASN B 2 289 ? 128.169 100.847 169.094 1.00 91.98  ? 290 ASN A C   1 
ATOM 2817 O O   . ASN B 2 289 ? 129.380 100.689 168.912 1.00 97.55  ? 290 ASN A O   1 
ATOM 2818 C CB  . ASN B 2 289 ? 127.681 103.018 170.234 1.00 91.64  ? 290 ASN A CB  1 
ATOM 2819 C CG  . ASN B 2 289 ? 129.123 103.217 170.648 1.00 94.92  ? 290 ASN A CG  1 
ATOM 2820 O OD1 . ASN B 2 289 ? 129.810 104.099 170.136 1.00 92.43  ? 290 ASN A OD1 1 
ATOM 2821 N ND2 . ASN B 2 289 ? 129.591 102.392 171.576 1.00 95.77  ? 290 ASN A ND2 1 
ATOM 2822 N N   . SER B 2 290 ? 127.363 99.841  169.432 1.00 85.85  ? 291 SER A N   1 
ATOM 2823 C CA  . SER B 2 290 ? 127.834 98.471  169.574 1.00 88.20  ? 291 SER A CA  1 
ATOM 2824 C C   . SER B 2 290 ? 127.410 97.590  168.405 1.00 85.45  ? 291 SER A C   1 
ATOM 2825 O O   . SER B 2 290 ? 127.379 96.362  168.541 1.00 90.64  ? 291 SER A O   1 
ATOM 2826 C CB  . SER B 2 290 ? 127.339 97.876  170.892 1.00 86.78  ? 291 SER A CB  1 
ATOM 2827 O OG  . SER B 2 290 ? 127.783 96.540  171.044 1.00 89.89  ? 291 SER A OG  1 
ATOM 2828 N N   . ALA B 2 291 ? 127.079 98.194  167.263 1.00 75.16  ? 292 ALA A N   1 
ATOM 2829 C CA  . ALA B 2 291 ? 126.607 97.421  166.121 1.00 70.70  ? 292 ALA A CA  1 
ATOM 2830 C C   . ALA B 2 291 ? 127.682 96.479  165.598 1.00 83.57  ? 292 ALA A C   1 
ATOM 2831 O O   . ALA B 2 291 ? 127.385 95.343  165.213 1.00 93.23  ? 292 ALA A O   1 
ATOM 2832 C CB  . ALA B 2 291 ? 126.136 98.360  165.012 1.00 76.02  ? 292 ALA A CB  1 
ATOM 2833 N N   . PHE B 2 292 ? 128.934 96.926  165.581 1.00 91.83  ? 293 PHE A N   1 
ATOM 2834 C CA  . PHE B 2 292 ? 130.030 96.199  164.951 1.00 87.64  ? 293 PHE A CA  1 
ATOM 2835 C C   . PHE B 2 292 ? 131.074 95.741  165.965 1.00 81.76  ? 293 PHE A C   1 
ATOM 2836 O O   . PHE B 2 292 ? 132.278 95.879  165.745 1.00 92.48  ? 293 PHE A O   1 
ATOM 2837 C CB  . PHE B 2 292 ? 130.684 97.049  163.867 1.00 81.50  ? 293 PHE A CB  1 
ATOM 2838 C CG  . PHE B 2 292 ? 129.778 97.355  162.714 1.00 77.49  ? 293 PHE A CG  1 
ATOM 2839 C CD1 . PHE B 2 292 ? 129.509 96.394  161.757 1.00 73.70  ? 293 PHE A CD1 1 
ATOM 2840 C CD2 . PHE B 2 292 ? 129.195 98.601  162.587 1.00 79.56  ? 293 PHE A CD2 1 
ATOM 2841 C CE1 . PHE B 2 292 ? 128.676 96.671  160.695 1.00 76.62  ? 293 PHE A CE1 1 
ATOM 2842 C CE2 . PHE B 2 292 ? 128.361 98.883  161.527 1.00 82.17  ? 293 PHE A CE2 1 
ATOM 2843 C CZ  . PHE B 2 292 ? 128.102 97.917  160.580 1.00 81.42  ? 293 PHE A CZ  1 
ATOM 2844 N N   . HIS B 2 293 ? 130.626 95.196  167.089 1.00 70.54  ? 294 HIS A N   1 
ATOM 2845 C CA  . HIS B 2 293 ? 131.520 94.646  168.093 1.00 72.27  ? 294 HIS A CA  1 
ATOM 2846 C C   . HIS B 2 293 ? 131.371 93.131  168.146 1.00 79.96  ? 294 HIS A C   1 
ATOM 2847 O O   . HIS B 2 293 ? 130.333 92.573  167.782 1.00 85.79  ? 294 HIS A O   1 
ATOM 2848 C CB  . HIS B 2 293 ? 131.245 95.259  169.471 1.00 72.62  ? 294 HIS A CB  1 
ATOM 2849 C CG  . HIS B 2 293 ? 130.399 94.403  170.359 1.00 81.28  ? 294 HIS A CG  1 
ATOM 2850 N ND1 . HIS B 2 293 ? 129.022 94.404  170.304 1.00 88.55  ? 294 HIS A ND1 1 
ATOM 2851 C CD2 . HIS B 2 293 ? 130.735 93.525  171.334 1.00 85.69  ? 294 HIS A CD2 1 
ATOM 2852 C CE1 . HIS B 2 293 ? 128.547 93.560  171.201 1.00 87.69  ? 294 HIS A CE1 1 
ATOM 2853 N NE2 . HIS B 2 293 ? 129.565 93.014  171.840 1.00 89.71  ? 294 HIS A NE2 1 
ATOM 2854 N N   . ASN B 2 294 ? 132.443 92.472  168.587 1.00 91.93  ? 295 ASN A N   1 
ATOM 2855 C CA  . ASN B 2 294 ? 132.557 91.022  168.721 1.00 92.55  ? 295 ASN A CA  1 
ATOM 2856 C C   . ASN B 2 294 ? 132.550 90.293  167.383 1.00 94.98  ? 295 ASN A C   1 
ATOM 2857 O O   . ASN B 2 294 ? 132.394 89.066  167.358 1.00 94.75  ? 295 ASN A O   1 
ATOM 2858 C CB  . ASN B 2 294 ? 131.461 90.440  169.622 1.00 95.10  ? 295 ASN A CB  1 
ATOM 2859 C CG  . ASN B 2 294 ? 131.930 89.225  170.398 1.00 96.39  ? 295 ASN A CG  1 
ATOM 2860 O OD1 . ASN B 2 294 ? 133.082 88.810  170.284 1.00 92.11  ? 295 ASN A OD1 1 
ATOM 2861 N ND2 . ASN B 2 294 ? 131.037 88.650  171.195 1.00 92.23  ? 295 ASN A ND2 1 
ATOM 2862 N N   . LEU B 2 295 ? 132.714 91.004  166.269 1.00 83.77  ? 296 LEU A N   1 
ATOM 2863 C CA  . LEU B 2 295 ? 132.900 90.369  164.964 1.00 79.55  ? 296 LEU A CA  1 
ATOM 2864 C C   . LEU B 2 295 ? 134.397 90.172  164.770 1.00 90.86  ? 296 LEU A C   1 
ATOM 2865 O O   . LEU B 2 295 ? 135.106 91.053  164.285 1.00 93.72  ? 296 LEU A O   1 
ATOM 2866 C CB  . LEU B 2 295 ? 132.292 91.210  163.850 1.00 75.45  ? 296 LEU A CB  1 
ATOM 2867 C CG  . LEU B 2 295 ? 131.022 91.998  164.169 1.00 79.54  ? 296 LEU A CG  1 
ATOM 2868 C CD1 . LEU B 2 295 ? 130.640 92.875  162.992 1.00 85.19  ? 296 LEU A CD1 1 
ATOM 2869 C CD2 . LEU B 2 295 ? 129.885 91.058  164.526 1.00 86.38  ? 296 LEU A CD2 1 
ATOM 2870 N N   . SER B 2 296 ? 134.886 88.994  165.160 1.00 95.25  ? 297 SER A N   1 
ATOM 2871 C CA  . SER B 2 296 ? 136.325 88.756  165.155 1.00 91.26  ? 297 SER A CA  1 
ATOM 2872 C C   . SER B 2 296 ? 137.004 88.695  163.792 1.00 95.67  ? 297 SER A C   1 
ATOM 2873 O O   . SER B 2 296 ? 138.137 89.164  163.638 1.00 97.93  ? 297 SER A O   1 
ATOM 2874 C CB  . SER B 2 296 ? 136.651 87.503  165.967 1.00 89.74  ? 297 SER A CB  1 
ATOM 2875 O OG  . SER B 2 296 ? 136.082 86.351  165.371 1.00 96.45  ? 297 SER A OG  1 
ATOM 2876 N N   . ASP B 2 297 ? 136.336 88.123  162.795 1.00 98.32  ? 298 ASP A N   1 
ATOM 2877 C CA  . ASP B 2 297 ? 136.930 87.944  161.478 1.00 91.51  ? 298 ASP A CA  1 
ATOM 2878 C C   . ASP B 2 297 ? 136.398 88.938  160.411 1.00 93.31  ? 298 ASP A C   1 
ATOM 2879 O O   . ASP B 2 297 ? 136.547 88.750  159.200 1.00 94.38  ? 298 ASP A O   1 
ATOM 2880 C CB  . ASP B 2 297 ? 136.596 86.560  160.919 1.00 92.27  ? 298 ASP A CB  1 
ATOM 2881 C CG  . ASP B 2 297 ? 137.331 85.452  161.638 1.00 99.04  ? 298 ASP A CG  1 
ATOM 2882 O OD1 . ASP B 2 297 ? 138.299 85.756  162.364 1.00 104.91 ? 298 ASP A OD1 1 
ATOM 2883 O OD2 . ASP B 2 297 ? 136.944 84.276  161.476 1.00 100.81 ? 298 ASP A OD2 1 
ATOM 2884 N N   . LEU B 2 298 ? 135.776 90.011  160.890 1.00 80.07  ? 299 LEU A N   1 
ATOM 2885 C CA  . LEU B 2 298 ? 135.281 91.044  159.991 1.00 76.87  ? 299 LEU A CA  1 
ATOM 2886 C C   . LEU B 2 298 ? 136.566 91.724  159.539 1.00 79.15  ? 299 LEU A C   1 
ATOM 2887 O O   . LEU B 2 298 ? 137.421 92.066  160.360 1.00 90.03  ? 299 LEU A O   1 
ATOM 2888 C CB  . LEU B 2 298 ? 134.351 92.051  160.661 1.00 73.55  ? 299 LEU A CB  1 
ATOM 2889 C CG  . LEU B 2 298 ? 133.909 93.231  159.798 1.00 70.11  ? 299 LEU A CG  1 
ATOM 2890 C CD1 . LEU B 2 298 ? 133.041 92.756  158.651 1.00 72.31  ? 299 LEU A CD1 1 
ATOM 2891 C CD2 . LEU B 2 298 ? 133.170 94.253  160.637 1.00 75.36  ? 299 LEU A CD2 1 
ATOM 2892 N N   . HIS B 2 299 ? 136.701 91.923  158.228 1.00 85.90  ? 300 HIS A N   1 
ATOM 2893 C CA  . HIS B 2 299 ? 137.925 92.458  157.653 1.00 85.53  ? 300 HIS A CA  1 
ATOM 2894 C C   . HIS B 2 299 ? 137.750 93.819  156.997 1.00 84.19  ? 300 HIS A C   1 
ATOM 2895 O O   . HIS B 2 299 ? 138.740 94.397  156.536 1.00 90.17  ? 300 HIS A O   1 
ATOM 2896 C CB  . HIS B 2 299 ? 138.502 91.473  156.628 1.00 88.36  ? 300 HIS A CB  1 
ATOM 2897 C CG  . HIS B 2 299 ? 138.050 91.729  155.225 1.00 100.87 ? 300 HIS A CG  1 
ATOM 2898 N ND1 . HIS B 2 299 ? 136.733 91.624  154.836 1.00 104.59 ? 300 HIS A ND1 1 
ATOM 2899 C CD2 . HIS B 2 299 ? 138.743 92.090  154.117 1.00 100.90 ? 300 HIS A CD2 1 
ATOM 2900 C CE1 . HIS B 2 299 ? 136.633 91.907  153.549 1.00 100.40 ? 300 HIS A CE1 1 
ATOM 2901 N NE2 . HIS B 2 299 ? 137.836 92.192  153.089 1.00 107.32 ? 300 HIS A NE2 1 
ATOM 2902 N N   . SER B 2 300 ? 136.532 94.351  156.940 1.00 85.71  ? 301 SER A N   1 
ATOM 2903 C CA  . SER B 2 300 ? 136.305 95.653  156.335 1.00 85.24  ? 301 SER A CA  1 
ATOM 2904 C C   . SER B 2 300 ? 135.065 96.278  156.954 1.00 94.63  ? 301 SER A C   1 
ATOM 2905 O O   . SER B 2 300 ? 134.219 95.590  157.528 1.00 103.17 ? 301 SER A O   1 
ATOM 2906 C CB  . SER B 2 300 ? 136.151 95.550  154.815 1.00 86.78  ? 301 SER A CB  1 
ATOM 2907 O OG  . SER B 2 300 ? 135.323 96.585  154.317 1.00 91.64  ? 301 SER A OG  1 
ATOM 2908 N N   . LEU B 2 301 ? 134.967 97.598  156.826 1.00 75.65  ? 302 LEU A N   1 
ATOM 2909 C CA  . LEU B 2 301 ? 133.835 98.335  157.378 1.00 62.63  ? 302 LEU A CA  1 
ATOM 2910 C C   . LEU B 2 301 ? 133.742 99.669  156.660 1.00 68.81  ? 302 LEU A C   1 
ATOM 2911 O O   . LEU B 2 301 ? 134.652 100.495 156.774 1.00 80.53  ? 302 LEU A O   1 
ATOM 2912 C CB  . LEU B 2 301 ? 134.001 98.539  158.882 1.00 58.94  ? 302 LEU A CB  1 
ATOM 2913 C CG  . LEU B 2 301 ? 132.798 99.089  159.644 1.00 67.77  ? 302 LEU A CG  1 
ATOM 2914 C CD1 . LEU B 2 301 ? 131.506 98.534  159.077 1.00 78.44  ? 302 LEU A CD1 1 
ATOM 2915 C CD2 . LEU B 2 301 ? 132.914 98.770  161.122 1.00 72.98  ? 302 LEU A CD2 1 
ATOM 2916 N N   . VAL B 2 302 ? 132.655 99.881  155.925 1.00 77.72  ? 303 VAL A N   1 
ATOM 2917 C CA  . VAL B 2 302 ? 132.437 101.114 155.179 1.00 85.37  ? 303 VAL A CA  1 
ATOM 2918 C C   . VAL B 2 302 ? 131.050 101.636 155.524 1.00 86.56  ? 303 VAL A C   1 
ATOM 2919 O O   . VAL B 2 302 ? 130.045 100.982 155.223 1.00 88.88  ? 303 VAL A O   1 
ATOM 2920 C CB  . VAL B 2 302 ? 132.574 100.902 153.662 1.00 86.06  ? 303 VAL A CB  1 
ATOM 2921 C CG1 . VAL B 2 302 ? 132.015 102.095 152.907 1.00 88.45  ? 303 VAL A CG1 1 
ATOM 2922 C CG2 . VAL B 2 302 ? 134.026 100.664 153.292 1.00 75.26  ? 303 VAL A CG2 1 
ATOM 2923 N N   . ILE B 2 303 ? 130.996 102.807 156.153 1.00 74.93  ? 304 ILE A N   1 
ATOM 2924 C CA  . ILE B 2 303 ? 129.744 103.451 156.529 1.00 65.30  ? 304 ILE A CA  1 
ATOM 2925 C C   . ILE B 2 303 ? 129.779 104.878 156.005 1.00 70.58  ? 304 ILE A C   1 
ATOM 2926 O O   . ILE B 2 303 ? 130.694 105.640 156.336 1.00 85.86  ? 304 ILE A O   1 
ATOM 2927 C CB  . ILE B 2 303 ? 129.522 103.438 158.049 1.00 64.64  ? 304 ILE A CB  1 
ATOM 2928 C CG1 . ILE B 2 303 ? 129.593 102.010 158.585 1.00 66.13  ? 304 ILE A CG1 1 
ATOM 2929 C CG2 . ILE B 2 303 ? 128.189 104.070 158.395 1.00 77.88  ? 304 ILE A CG2 1 
ATOM 2930 C CD1 . ILE B 2 303 ? 129.588 101.928 160.090 1.00 75.21  ? 304 ILE A CD1 1 
ATOM 2931 N N   . ARG B 2 304 ? 128.791 105.239 155.193 1.00 81.81  ? 305 ARG A N   1 
ATOM 2932 C CA  . ARG B 2 304 ? 128.710 106.566 154.604 1.00 79.84  ? 305 ARG A CA  1 
ATOM 2933 C C   . ARG B 2 304 ? 127.305 107.120 154.777 1.00 88.89  ? 305 ARG A C   1 
ATOM 2934 O O   . ARG B 2 304 ? 126.318 106.406 154.582 1.00 93.67  ? 305 ARG A O   1 
ATOM 2935 C CB  . ARG B 2 304 ? 129.078 106.541 153.116 1.00 80.34  ? 305 ARG A CB  1 
ATOM 2936 C CG  . ARG B 2 304 ? 130.473 106.020 152.824 1.00 79.39  ? 305 ARG A CG  1 
ATOM 2937 C CD  . ARG B 2 304 ? 130.720 105.927 151.328 1.00 88.99  ? 305 ARG A CD  1 
ATOM 2938 N NE  . ARG B 2 304 ? 132.034 105.373 151.021 1.00 91.41  ? 305 ARG A NE  1 
ATOM 2939 C CZ  . ARG B 2 304 ? 133.151 106.085 150.960 1.00 92.03  ? 305 ARG A CZ  1 
ATOM 2940 N NH1 . ARG B 2 304 ? 133.152 107.389 151.178 1.00 90.82  ? 305 ARG A NH1 1 
ATOM 2941 N NH2 . ARG B 2 304 ? 134.295 105.471 150.673 1.00 89.31  ? 305 ARG A NH2 1 
ATOM 2942 N N   . GLY B 2 305 ? 127.221 108.397 155.143 1.00 83.11  ? 306 GLY A N   1 
ATOM 2943 C CA  . GLY B 2 305 ? 125.953 109.084 155.246 1.00 75.01  ? 306 GLY A CA  1 
ATOM 2944 C C   . GLY B 2 305 ? 125.268 109.006 156.592 1.00 79.33  ? 306 GLY A C   1 
ATOM 2945 O O   . GLY B 2 305 ? 124.236 109.663 156.776 1.00 86.27  ? 306 GLY A O   1 
ATOM 2946 N N   . ALA B 2 306 ? 125.812 108.252 157.546 1.00 79.13  ? 307 ALA A N   1 
ATOM 2947 C CA  . ALA B 2 306 ? 125.172 108.066 158.849 1.00 87.33  ? 307 ALA A CA  1 
ATOM 2948 C C   . ALA B 2 306 ? 125.332 109.353 159.653 1.00 89.67  ? 307 ALA A C   1 
ATOM 2949 O O   . ALA B 2 306 ? 126.186 109.481 160.533 1.00 96.74  ? 307 ALA A O   1 
ATOM 2950 C CB  . ALA B 2 306 ? 125.773 106.871 159.577 1.00 86.39  ? 307 ALA A CB  1 
ATOM 2951 N N   . SER B 2 307 ? 124.469 110.324 159.346 1.00 88.26  ? 308 SER A N   1 
ATOM 2952 C CA  . SER B 2 307 ? 124.664 111.689 159.822 1.00 89.24  ? 308 SER A CA  1 
ATOM 2953 C C   . SER B 2 307 ? 124.352 111.865 161.303 1.00 92.40  ? 308 SER A C   1 
ATOM 2954 O O   . SER B 2 307 ? 124.734 112.889 161.878 1.00 96.15  ? 308 SER A O   1 
ATOM 2955 C CB  . SER B 2 307 ? 123.808 112.651 159.001 1.00 100.22 ? 308 SER A CB  1 
ATOM 2956 O OG  . SER B 2 307 ? 122.445 112.554 159.371 1.00 110.94 ? 308 SER A OG  1 
ATOM 2957 N N   . MET B 2 308 ? 123.675 110.912 161.935 1.00 97.51  ? 309 MET A N   1 
ATOM 2958 C CA  . MET B 2 308 ? 123.346 111.037 163.349 1.00 99.60  ? 309 MET A CA  1 
ATOM 2959 C C   . MET B 2 308 ? 124.359 110.360 164.262 1.00 106.40 ? 309 MET A C   1 
ATOM 2960 O O   . MET B 2 308 ? 124.141 110.313 165.476 1.00 108.73 ? 309 MET A O   1 
ATOM 2961 C CB  . MET B 2 308 ? 121.950 110.471 163.624 1.00 101.17 ? 309 MET A CB  1 
ATOM 2962 C CG  . MET B 2 308 ? 121.090 111.356 164.507 1.00 100.56 ? 309 MET A CG  1 
ATOM 2963 S SD  . MET B 2 308 ? 120.943 113.035 163.870 1.00 115.62 ? 309 MET A SD  1 
ATOM 2964 C CE  . MET B 2 308 ? 120.274 112.720 162.239 1.00 104.46 ? 309 MET A CE  1 
ATOM 2965 N N   . VAL B 2 309 ? 125.450 109.834 163.716 1.00 91.96  ? 310 VAL A N   1 
ATOM 2966 C CA  . VAL B 2 309 ? 126.504 109.222 164.515 1.00 83.70  ? 310 VAL A CA  1 
ATOM 2967 C C   . VAL B 2 309 ? 127.441 110.318 165.000 1.00 88.18  ? 310 VAL A C   1 
ATOM 2968 O O   . VAL B 2 309 ? 127.863 111.176 164.217 1.00 92.97  ? 310 VAL A O   1 
ATOM 2969 C CB  . VAL B 2 309 ? 127.266 108.162 163.705 1.00 86.25  ? 310 VAL A CB  1 
ATOM 2970 C CG1 . VAL B 2 309 ? 128.344 107.520 164.558 1.00 95.93  ? 310 VAL A CG1 1 
ATOM 2971 C CG2 . VAL B 2 309 ? 126.307 107.111 163.183 1.00 87.48  ? 310 VAL A CG2 1 
ATOM 2972 N N   . GLN B 2 310 ? 127.763 110.296 166.293 1.00 98.28  ? 311 GLN A N   1 
ATOM 2973 C CA  . GLN B 2 310 ? 128.627 111.307 166.881 1.00 99.73  ? 311 GLN A CA  1 
ATOM 2974 C C   . GLN B 2 310 ? 129.747 110.737 167.739 1.00 100.29 ? 311 GLN A C   1 
ATOM 2975 O O   . GLN B 2 310 ? 130.578 111.509 168.228 1.00 108.00 ? 311 GLN A O   1 
ATOM 2976 C CB  . GLN B 2 310 ? 127.802 112.293 167.721 1.00 98.32  ? 311 GLN A CB  1 
ATOM 2977 C CG  . GLN B 2 310 ? 127.088 111.658 168.897 1.00 101.73 ? 311 GLN A CG  1 
ATOM 2978 C CD  . GLN B 2 310 ? 125.844 112.421 169.297 1.00 107.42 ? 311 GLN A CD  1 
ATOM 2979 O OE1 . GLN B 2 310 ? 125.517 113.451 168.706 1.00 105.93 ? 311 GLN A OE1 1 
ATOM 2980 N NE2 . GLN B 2 310 ? 125.140 111.919 170.304 1.00 107.97 ? 311 GLN A NE2 1 
ATOM 2981 N N   . GLN B 2 311 ? 129.799 109.423 167.940 1.00 88.41  ? 312 GLN A N   1 
ATOM 2982 C CA  . GLN B 2 311 ? 130.882 108.795 168.679 1.00 92.17  ? 312 GLN A CA  1 
ATOM 2983 C C   . GLN B 2 311 ? 131.395 107.592 167.902 1.00 96.04  ? 312 GLN A C   1 
ATOM 2984 O O   . GLN B 2 311 ? 130.661 106.977 167.124 1.00 97.23  ? 312 GLN A O   1 
ATOM 2985 C CB  . GLN B 2 311 ? 130.438 108.367 170.083 1.00 89.98  ? 312 GLN A CB  1 
ATOM 2986 C CG  . GLN B 2 311 ? 129.344 107.322 170.101 1.00 94.76  ? 312 GLN A CG  1 
ATOM 2987 C CD  . GLN B 2 311 ? 128.724 107.162 171.473 1.00 102.85 ? 312 GLN A CD  1 
ATOM 2988 O OE1 . GLN B 2 311 ? 128.274 106.078 171.841 1.00 105.14 ? 312 GLN A OE1 1 
ATOM 2989 N NE2 . GLN B 2 311 ? 128.698 108.245 172.239 1.00 99.68  ? 312 GLN A NE2 1 
ATOM 2990 N N   . PHE B 2 312 ? 132.667 107.272 168.112 1.00 87.76  ? 313 PHE A N   1 
ATOM 2991 C CA  . PHE B 2 312 ? 133.285 106.180 167.376 1.00 87.84  ? 313 PHE A CA  1 
ATOM 2992 C C   . PHE B 2 312 ? 132.667 104.846 167.789 1.00 94.20  ? 313 PHE A C   1 
ATOM 2993 O O   . PHE B 2 312 ? 132.363 104.640 168.968 1.00 96.69  ? 313 PHE A O   1 
ATOM 2994 C CB  . PHE B 2 312 ? 134.791 106.154 167.615 1.00 81.17  ? 313 PHE A CB  1 
ATOM 2995 C CG  . PHE B 2 312 ? 135.596 105.973 166.362 1.00 79.95  ? 313 PHE A CG  1 
ATOM 2996 C CD1 . PHE B 2 312 ? 135.762 107.020 165.475 1.00 86.19  ? 313 PHE A CD1 1 
ATOM 2997 C CD2 . PHE B 2 312 ? 136.183 104.756 166.071 1.00 81.30  ? 313 PHE A CD2 1 
ATOM 2998 C CE1 . PHE B 2 312 ? 136.500 106.856 164.322 1.00 90.81  ? 313 PHE A CE1 1 
ATOM 2999 C CE2 . PHE B 2 312 ? 136.923 104.588 164.919 1.00 90.59  ? 313 PHE A CE2 1 
ATOM 3000 C CZ  . PHE B 2 312 ? 137.080 105.639 164.044 1.00 93.51  ? 313 PHE A CZ  1 
ATOM 3001 N N   . PRO B 2 313 ? 132.464 103.928 166.845 1.00 76.75  ? 314 PRO A N   1 
ATOM 3002 C CA  . PRO B 2 313 ? 131.829 102.650 167.181 1.00 78.50  ? 314 PRO A CA  1 
ATOM 3003 C C   . PRO B 2 313 ? 132.670 101.836 168.151 1.00 81.23  ? 314 PRO A C   1 
ATOM 3004 O O   . PRO B 2 313 ? 133.902 101.874 168.128 1.00 79.39  ? 314 PRO A O   1 
ATOM 3005 C CB  . PRO B 2 313 ? 131.709 101.945 165.824 1.00 70.53  ? 314 PRO A CB  1 
ATOM 3006 C CG  . PRO B 2 313 ? 131.836 103.029 164.808 1.00 63.59  ? 314 PRO A CG  1 
ATOM 3007 C CD  . PRO B 2 313 ? 132.752 104.041 165.408 1.00 65.75  ? 314 PRO A CD  1 
ATOM 3008 N N   . ASN B 2 314 ? 131.983 101.094 169.014 1.00 80.52  ? 315 ASN A N   1 
ATOM 3009 C CA  . ASN B 2 314 ? 132.641 100.148 169.911 1.00 74.46  ? 315 ASN A CA  1 
ATOM 3010 C C   . ASN B 2 314 ? 133.164 98.994  169.069 1.00 75.35  ? 315 ASN A C   1 
ATOM 3011 O O   . ASN B 2 314 ? 132.401 98.132  168.631 1.00 83.18  ? 315 ASN A O   1 
ATOM 3012 C CB  . ASN B 2 314 ? 131.671 99.665  170.982 1.00 77.17  ? 315 ASN A CB  1 
ATOM 3013 C CG  . ASN B 2 314 ? 132.365 98.946  172.121 1.00 80.49  ? 315 ASN A CG  1 
ATOM 3014 O OD1 . ASN B 2 314 ? 133.519 98.538  172.003 1.00 85.47  ? 315 ASN A OD1 1 
ATOM 3015 N ND2 . ASN B 2 314 ? 131.660 98.787  173.235 1.00 69.72  ? 315 ASN A ND2 1 
ATOM 3016 N N   . LEU B 2 315 ? 134.472 98.979  168.828 1.00 75.07  ? 316 LEU A N   1 
ATOM 3017 C CA  . LEU B 2 315 ? 135.095 97.984  167.968 1.00 81.38  ? 316 LEU A CA  1 
ATOM 3018 C C   . LEU B 2 315 ? 135.807 96.890  168.749 1.00 80.82  ? 316 LEU A C   1 
ATOM 3019 O O   . LEU B 2 315 ? 136.576 96.126  168.159 1.00 84.91  ? 316 LEU A O   1 
ATOM 3020 C CB  . LEU B 2 315 ? 136.071 98.660  167.005 1.00 79.17  ? 316 LEU A CB  1 
ATOM 3021 C CG  . LEU B 2 315 ? 135.439 99.262  165.750 1.00 77.56  ? 316 LEU A CG  1 
ATOM 3022 C CD1 . LEU B 2 315 ? 136.481 99.985  164.921 1.00 79.04  ? 316 LEU A CD1 1 
ATOM 3023 C CD2 . LEU B 2 315 ? 134.754 98.183  164.932 1.00 72.81  ? 316 LEU A CD2 1 
ATOM 3024 N N   . THR B 2 316 ? 135.579 96.803  170.057 1.00 88.66  ? 317 THR A N   1 
ATOM 3025 C CA  . THR B 2 316 ? 136.183 95.742  170.850 1.00 91.57  ? 317 THR A CA  1 
ATOM 3026 C C   . THR B 2 316 ? 135.751 94.382  170.320 1.00 89.61  ? 317 THR A C   1 
ATOM 3027 O O   . THR B 2 316 ? 134.564 94.137  170.095 1.00 95.52  ? 317 THR A O   1 
ATOM 3028 C CB  . THR B 2 316 ? 135.789 95.891  172.319 1.00 99.67  ? 317 THR A CB  1 
ATOM 3029 O OG1 . THR B 2 316 ? 136.454 97.031  172.878 1.00 100.43 ? 317 THR A OG1 1 
ATOM 3030 C CG2 . THR B 2 316 ? 136.177 94.651  173.108 1.00 97.43  ? 317 THR A CG2 1 
ATOM 3031 N N   . GLY B 2 317 ? 136.724 93.497  170.119 1.00 87.48  ? 318 GLY A N   1 
ATOM 3032 C CA  . GLY B 2 317 ? 136.485 92.218  169.498 1.00 88.83  ? 318 GLY A CA  1 
ATOM 3033 C C   . GLY B 2 317 ? 136.688 92.200  167.999 1.00 93.57  ? 318 GLY A C   1 
ATOM 3034 O O   . GLY B 2 317 ? 136.812 91.118  167.417 1.00 98.97  ? 318 GLY A O   1 
ATOM 3035 N N   . THR B 2 318 ? 136.727 93.366  167.360 1.00 89.16  ? 319 THR A N   1 
ATOM 3036 C CA  . THR B 2 318 ? 136.983 93.479  165.926 1.00 86.32  ? 319 THR A CA  1 
ATOM 3037 C C   . THR B 2 318 ? 138.438 93.902  165.762 1.00 91.59  ? 319 THR A C   1 
ATOM 3038 O O   . THR B 2 318 ? 138.769 95.087  165.800 1.00 94.08  ? 319 THR A O   1 
ATOM 3039 C CB  . THR B 2 318 ? 136.029 94.475  165.281 1.00 77.44  ? 319 THR A CB  1 
ATOM 3040 O OG1 . THR B 2 318 ? 134.690 94.190  165.698 1.00 85.75  ? 319 THR A OG1 1 
ATOM 3041 C CG2 . THR B 2 318 ? 136.105 94.376  163.773 1.00 77.75  ? 319 THR A CG2 1 
ATOM 3042 N N   . VAL B 2 319 ? 139.317 92.920  165.574 1.00 90.79  ? 320 VAL A N   1 
ATOM 3043 C CA  . VAL B 2 319 ? 140.753 93.171  165.525 1.00 85.65  ? 320 VAL A CA  1 
ATOM 3044 C C   . VAL B 2 319 ? 141.372 92.839  164.179 1.00 97.31  ? 320 VAL A C   1 
ATOM 3045 O O   . VAL B 2 319 ? 142.542 93.189  163.954 1.00 104.86 ? 320 VAL A O   1 
ATOM 3046 C CB  . VAL B 2 319 ? 141.494 92.407  166.642 1.00 90.01  ? 320 VAL A CB  1 
ATOM 3047 C CG1 . VAL B 2 319 ? 141.176 93.016  167.994 1.00 93.69  ? 320 VAL A CG1 1 
ATOM 3048 C CG2 . VAL B 2 319 ? 141.117 90.937  166.614 1.00 85.33  ? 320 VAL A CG2 1 
ATOM 3049 N N   . HIS B 2 320 ? 140.644 92.179  163.279 1.00 99.09  ? 321 HIS A N   1 
ATOM 3050 C CA  . HIS B 2 320 ? 141.163 91.824  161.964 1.00 93.51  ? 321 HIS A CA  1 
ATOM 3051 C C   . HIS B 2 320 ? 140.673 92.771  160.877 1.00 93.98  ? 321 HIS A C   1 
ATOM 3052 O O   . HIS B 2 320 ? 140.490 92.357  159.728 1.00 97.05  ? 321 HIS A O   1 
ATOM 3053 C CB  . HIS B 2 320 ? 140.795 90.383  161.616 1.00 91.54  ? 321 HIS A CB  1 
ATOM 3054 C CG  . HIS B 2 320 ? 141.388 89.370  162.542 1.00 101.13 ? 321 HIS A CG  1 
ATOM 3055 N ND1 . HIS B 2 320 ? 142.196 89.715  163.604 1.00 105.22 ? 321 HIS A ND1 1 
ATOM 3056 C CD2 . HIS B 2 320 ? 141.296 88.019  162.563 1.00 103.04 ? 321 HIS A CD2 1 
ATOM 3057 C CE1 . HIS B 2 320 ? 142.573 88.621  164.241 1.00 105.13 ? 321 HIS A CE1 1 
ATOM 3058 N NE2 . HIS B 2 320 ? 142.040 87.579  163.630 1.00 107.24 ? 321 HIS A NE2 1 
ATOM 3059 N N   . LEU B 2 321 ? 140.459 94.037  161.217 1.00 78.28  ? 322 LEU A N   1 
ATOM 3060 C CA  . LEU B 2 321 ? 139.974 95.010  160.252 1.00 80.13  ? 322 LEU A CA  1 
ATOM 3061 C C   . LEU B 2 321 ? 141.112 95.471  159.352 1.00 84.75  ? 322 LEU A C   1 
ATOM 3062 O O   . LEU B 2 321 ? 142.197 95.813  159.832 1.00 89.96  ? 322 LEU A O   1 
ATOM 3063 C CB  . LEU B 2 321 ? 139.350 96.204  160.970 1.00 76.77  ? 322 LEU A CB  1 
ATOM 3064 C CG  . LEU B 2 321 ? 138.042 96.718  160.374 1.00 76.95  ? 322 LEU A CG  1 
ATOM 3065 C CD1 . LEU B 2 321 ? 136.959 95.670  160.501 1.00 80.23  ? 322 LEU A CD1 1 
ATOM 3066 C CD2 . LEU B 2 321 ? 137.616 98.001  161.054 1.00 83.94  ? 322 LEU A CD2 1 
ATOM 3067 N N   . GLU B 2 322 ? 140.865 95.472  158.044 1.00 95.76  ? 323 GLU A N   1 
ATOM 3068 C CA  . GLU B 2 322 ? 141.826 95.979  157.075 1.00 85.12  ? 323 GLU A CA  1 
ATOM 3069 C C   . GLU B 2 322 ? 141.489 97.374  156.576 1.00 85.63  ? 323 GLU A C   1 
ATOM 3070 O O   . GLU B 2 322 ? 142.403 98.160  156.309 1.00 87.79  ? 323 GLU A O   1 
ATOM 3071 C CB  . GLU B 2 322 ? 141.924 95.032  155.876 1.00 91.27  ? 323 GLU A CB  1 
ATOM 3072 C CG  . GLU B 2 322 ? 142.653 93.735  156.169 1.00 100.59 ? 323 GLU A CG  1 
ATOM 3073 C CD  . GLU B 2 322 ? 142.595 92.762  155.009 1.00 109.80 ? 323 GLU A CD  1 
ATOM 3074 O OE1 . GLU B 2 322 ? 142.004 93.113  153.966 1.00 109.26 ? 323 GLU A OE1 1 
ATOM 3075 O OE2 . GLU B 2 322 ? 143.141 91.646  155.139 1.00 111.44 ? 323 GLU A OE2 1 
ATOM 3076 N N   . SER B 2 323 ? 140.207 97.697  156.445 1.00 79.55  ? 324 SER A N   1 
ATOM 3077 C CA  . SER B 2 323 ? 139.767 99.010  156.005 1.00 80.41  ? 324 SER A CA  1 
ATOM 3078 C C   . SER B 2 323 ? 138.742 99.557  156.987 1.00 81.76  ? 324 SER A C   1 
ATOM 3079 O O   . SER B 2 323 ? 138.104 98.812  157.733 1.00 89.88  ? 324 SER A O   1 
ATOM 3080 C CB  . SER B 2 323 ? 139.170 98.963  154.594 1.00 81.06  ? 324 SER A CB  1 
ATOM 3081 O OG  . SER B 2 323 ? 139.946 98.141  153.742 1.00 85.88  ? 324 SER A OG  1 
ATOM 3082 N N   . LEU B 2 324 ? 138.595 100.879 156.980 1.00 59.52  ? 325 LEU A N   1 
ATOM 3083 C CA  . LEU B 2 324 ? 137.646 101.552 157.853 1.00 52.02  ? 325 LEU A CA  1 
ATOM 3084 C C   . LEU B 2 324 ? 137.252 102.861 157.192 1.00 59.31  ? 325 LEU A C   1 
ATOM 3085 O O   . LEU B 2 324 ? 138.122 103.658 156.832 1.00 68.55  ? 325 LEU A O   1 
ATOM 3086 C CB  . LEU B 2 324 ? 138.253 101.804 159.236 1.00 48.18  ? 325 LEU A CB  1 
ATOM 3087 C CG  . LEU B 2 324 ? 137.316 101.759 160.442 1.00 54.40  ? 325 LEU A CG  1 
ATOM 3088 C CD1 . LEU B 2 324 ? 138.120 101.613 161.717 1.00 54.50  ? 325 LEU A CD1 1 
ATOM 3089 C CD2 . LEU B 2 324 ? 136.453 102.999 160.505 1.00 65.47  ? 325 LEU A CD2 1 
ATOM 3090 N N   . THR B 2 325 ? 135.948 103.080 157.034 1.00 68.23  ? 326 THR A N   1 
ATOM 3091 C CA  . THR B 2 325 ? 135.440 104.250 156.317 1.00 68.70  ? 326 THR A CA  1 
ATOM 3092 C C   . THR B 2 325 ? 134.208 104.773 157.047 1.00 62.33  ? 326 THR A C   1 
ATOM 3093 O O   . THR B 2 325 ? 133.122 104.199 156.933 1.00 78.88  ? 326 THR A O   1 
ATOM 3094 C CB  . THR B 2 325 ? 135.116 103.909 154.868 1.00 70.58  ? 326 THR A CB  1 
ATOM 3095 O OG1 . THR B 2 325 ? 136.248 103.275 154.261 1.00 75.20  ? 326 THR A OG1 1 
ATOM 3096 C CG2 . THR B 2 325 ? 134.771 105.165 154.093 1.00 69.65  ? 326 THR A CG2 1 
ATOM 3097 N N   . LEU B 2 326 ? 134.383 105.861 157.791 1.00 52.29  ? 327 LEU A N   1 
ATOM 3098 C CA  . LEU B 2 326 ? 133.291 106.561 158.459 1.00 61.06  ? 327 LEU A CA  1 
ATOM 3099 C C   . LEU B 2 326 ? 133.220 107.964 157.872 1.00 63.80  ? 327 LEU A C   1 
ATOM 3100 O O   . LEU B 2 326 ? 134.023 108.832 158.228 1.00 66.31  ? 327 LEU A O   1 
ATOM 3101 C CB  . LEU B 2 326 ? 133.504 106.605 159.970 1.00 60.89  ? 327 LEU A CB  1 
ATOM 3102 C CG  . LEU B 2 326 ? 133.571 105.280 160.732 1.00 58.66  ? 327 LEU A CG  1 
ATOM 3103 C CD1 . LEU B 2 326 ? 133.160 105.498 162.170 1.00 71.27  ? 327 LEU A CD1 1 
ATOM 3104 C CD2 . LEU B 2 326 ? 132.692 104.222 160.095 1.00 68.10  ? 327 LEU A CD2 1 
ATOM 3105 N N   . THR B 2 327 ? 132.261 108.187 156.979 1.00 78.84  ? 328 THR A N   1 
ATOM 3106 C CA  . THR B 2 327 ? 132.181 109.417 156.204 1.00 76.83  ? 328 THR A CA  1 
ATOM 3107 C C   . THR B 2 327 ? 130.811 110.057 156.385 1.00 80.88  ? 328 THR A C   1 
ATOM 3108 O O   . THR B 2 327 ? 129.796 109.361 156.468 1.00 85.88  ? 328 THR A O   1 
ATOM 3109 C CB  . THR B 2 327 ? 132.456 109.130 154.716 1.00 81.56  ? 328 THR A CB  1 
ATOM 3110 O OG1 . THR B 2 327 ? 133.857 108.899 154.527 1.00 82.39  ? 328 THR A OG1 1 
ATOM 3111 C CG2 . THR B 2 327 ? 132.022 110.287 153.831 1.00 82.75  ? 328 THR A CG2 1 
ATOM 3112 N N   . GLY B 2 328 ? 130.791 111.384 156.449 1.00 81.04  ? 329 GLY A N   1 
ATOM 3113 C CA  . GLY B 2 328 ? 129.551 112.135 156.542 1.00 76.71  ? 329 GLY A CA  1 
ATOM 3114 C C   . GLY B 2 328 ? 128.808 111.982 157.849 1.00 77.83  ? 329 GLY A C   1 
ATOM 3115 O O   . GLY B 2 328 ? 127.571 111.959 157.856 1.00 93.30  ? 329 GLY A O   1 
ATOM 3116 N N   . THR B 2 329 ? 129.529 111.889 158.958 1.00 71.49  ? 330 THR A N   1 
ATOM 3117 C CA  . THR B 2 329 ? 128.941 111.784 160.285 1.00 79.41  ? 330 THR A CA  1 
ATOM 3118 C C   . THR B 2 329 ? 129.383 112.985 161.120 1.00 82.33  ? 330 THR A C   1 
ATOM 3119 O O   . THR B 2 329 ? 130.008 113.922 160.616 1.00 82.16  ? 330 THR A O   1 
ATOM 3120 C CB  . THR B 2 329 ? 129.327 110.460 160.946 1.00 85.87  ? 330 THR A CB  1 
ATOM 3121 O OG1 . THR B 2 329 ? 130.617 110.592 161.551 1.00 96.52  ? 330 THR A OG1 1 
ATOM 3122 C CG2 . THR B 2 329 ? 129.377 109.341 159.918 1.00 81.47  ? 330 THR A CG2 1 
ATOM 3123 N N   . LYS B 2 330 ? 129.046 112.959 162.408 1.00 94.95  ? 331 LYS A N   1 
ATOM 3124 C CA  . LYS B 2 330 ? 129.364 114.048 163.322 1.00 93.16  ? 331 LYS A CA  1 
ATOM 3125 C C   . LYS B 2 330 ? 130.353 113.625 164.404 1.00 92.63  ? 331 LYS A C   1 
ATOM 3126 O O   . LYS B 2 330 ? 130.333 114.164 165.512 1.00 95.17  ? 331 LYS A O   1 
ATOM 3127 C CB  . LYS B 2 330 ? 128.092 114.597 163.966 1.00 95.99  ? 331 LYS A CB  1 
ATOM 3128 C CG  . LYS B 2 330 ? 127.017 115.023 162.981 1.00 93.43  ? 331 LYS A CG  1 
ATOM 3129 C CD  . LYS B 2 330 ? 125.839 115.660 163.703 1.00 93.26  ? 331 LYS A CD  1 
ATOM 3130 C CE  . LYS B 2 330 ? 125.416 114.829 164.904 1.00 96.20  ? 331 LYS A CE  1 
ATOM 3131 N NZ  . LYS B 2 330 ? 124.306 115.467 165.662 1.00 94.78  ? 331 LYS A NZ  1 
ATOM 3132 N N   . ILE B 2 331 ? 131.222 112.661 164.102 1.00 87.08  ? 332 ILE A N   1 
ATOM 3133 C CA  . ILE B 2 331 ? 132.214 112.228 165.078 1.00 84.61  ? 332 ILE A CA  1 
ATOM 3134 C C   . ILE B 2 331 ? 133.312 113.275 165.175 1.00 85.21  ? 332 ILE A C   1 
ATOM 3135 O O   . ILE B 2 331 ? 133.822 113.763 164.159 1.00 90.53  ? 332 ILE A O   1 
ATOM 3136 C CB  . ILE B 2 331 ? 132.783 110.852 164.702 1.00 84.22  ? 332 ILE A CB  1 
ATOM 3137 C CG1 . ILE B 2 331 ? 133.184 110.818 163.230 1.00 84.48  ? 332 ILE A CG1 1 
ATOM 3138 C CG2 . ILE B 2 331 ? 131.769 109.762 164.993 1.00 86.61  ? 332 ILE A CG2 1 
ATOM 3139 C CD1 . ILE B 2 331 ? 133.656 109.464 162.766 1.00 87.69  ? 332 ILE A CD1 1 
ATOM 3140 N N   . SER B 2 332 ? 133.673 113.637 166.403 1.00 82.18  ? 333 SER A N   1 
ATOM 3141 C CA  . SER B 2 332 ? 134.705 114.631 166.643 1.00 85.84  ? 333 SER A CA  1 
ATOM 3142 C C   . SER B 2 332 ? 135.935 114.061 167.330 1.00 90.71  ? 333 SER A C   1 
ATOM 3143 O O   . SER B 2 332 ? 136.875 114.814 167.607 1.00 97.53  ? 333 SER A O   1 
ATOM 3144 C CB  . SER B 2 332 ? 134.145 115.786 167.482 1.00 90.64  ? 333 SER A CB  1 
ATOM 3145 O OG  . SER B 2 332 ? 133.552 115.304 168.674 1.00 85.92  ? 333 SER A OG  1 
ATOM 3146 N N   . SER B 2 333 ? 135.961 112.762 167.613 1.00 87.99  ? 334 SER A N   1 
ATOM 3147 C CA  . SER B 2 333 ? 137.079 112.147 168.308 1.00 88.29  ? 334 SER A CA  1 
ATOM 3148 C C   . SER B 2 333 ? 137.418 110.816 167.658 1.00 89.98  ? 334 SER A C   1 
ATOM 3149 O O   . SER B 2 333 ? 136.565 110.172 167.043 1.00 95.48  ? 334 SER A O   1 
ATOM 3150 C CB  . SER B 2 333 ? 136.767 111.934 169.794 1.00 89.98  ? 334 SER A CB  1 
ATOM 3151 O OG  . SER B 2 333 ? 136.259 110.631 170.021 1.00 86.33  ? 334 SER A OG  1 
ATOM 3152 N N   . ILE B 2 334 ? 138.676 110.416 167.800 1.00 87.09  ? 335 ILE A N   1 
ATOM 3153 C CA  . ILE B 2 334 ? 139.158 109.112 167.362 1.00 82.12  ? 335 ILE A CA  1 
ATOM 3154 C C   . ILE B 2 334 ? 139.786 108.435 168.572 1.00 84.68  ? 335 ILE A C   1 
ATOM 3155 O O   . ILE B 2 334 ? 140.601 109.054 169.257 1.00 88.37  ? 335 ILE A O   1 
ATOM 3156 C CB  . ILE B 2 334 ? 140.180 109.214 166.216 1.00 79.68  ? 335 ILE A CB  1 
ATOM 3157 C CG1 . ILE B 2 334 ? 139.819 110.361 165.274 1.00 86.30  ? 335 ILE A CG1 1 
ATOM 3158 C CG2 . ILE B 2 334 ? 140.245 107.912 165.442 1.00 81.68  ? 335 ILE A CG2 1 
ATOM 3159 C CD1 . ILE B 2 334 ? 140.819 110.570 164.161 1.00 82.72  ? 335 ILE A CD1 1 
ATOM 3160 N N   . PRO B 2 335 ? 139.432 107.188 168.880 1.00 86.18  ? 336 PRO A N   1 
ATOM 3161 C CA  . PRO B 2 335 ? 139.958 106.552 170.093 1.00 86.65  ? 336 PRO A CA  1 
ATOM 3162 C C   . PRO B 2 335 ? 141.474 106.440 170.056 1.00 91.86  ? 336 PRO A C   1 
ATOM 3163 O O   . PRO B 2 335 ? 142.074 106.191 169.010 1.00 96.44  ? 336 PRO A O   1 
ATOM 3164 C CB  . PRO B 2 335 ? 139.291 105.171 170.089 1.00 85.91  ? 336 PRO A CB  1 
ATOM 3165 C CG  . PRO B 2 335 ? 138.124 105.303 169.169 1.00 91.78  ? 336 PRO A CG  1 
ATOM 3166 C CD  . PRO B 2 335 ? 138.534 106.295 168.135 1.00 90.03  ? 336 PRO A CD  1 
ATOM 3167 N N   . ASN B 2 336 ? 142.092 106.629 171.222 1.00 104.52 ? 337 ASN A N   1 
ATOM 3168 C CA  . ASN B 2 336 ? 143.542 106.551 171.322 1.00 104.99 ? 337 ASN A CA  1 
ATOM 3169 C C   . ASN B 2 336 ? 144.065 105.127 171.204 1.00 108.22 ? 337 ASN A C   1 
ATOM 3170 O O   . ASN B 2 336 ? 145.276 104.943 171.046 1.00 108.35 ? 337 ASN A O   1 
ATOM 3171 C CB  . ASN B 2 336 ? 144.008 107.164 172.642 1.00 110.02 ? 337 ASN A CB  1 
ATOM 3172 C CG  . ASN B 2 336 ? 144.019 108.677 172.606 1.00 113.28 ? 337 ASN A CG  1 
ATOM 3173 O OD1 . ASN B 2 336 ? 144.933 109.291 172.056 1.00 109.38 ? 337 ASN A OD1 1 
ATOM 3174 N ND2 . ASN B 2 336 ? 142.997 109.289 173.192 1.00 112.52 ? 337 ASN A ND2 1 
ATOM 3175 N N   . ASN B 2 337 ? 143.193 104.123 171.281 1.00 109.49 ? 338 ASN A N   1 
ATOM 3176 C CA  . ASN B 2 337 ? 143.592 102.728 171.177 1.00 110.60 ? 338 ASN A CA  1 
ATOM 3177 C C   . ASN B 2 337 ? 143.246 102.115 169.826 1.00 110.35 ? 338 ASN A C   1 
ATOM 3178 O O   . ASN B 2 337 ? 143.386 100.900 169.657 1.00 116.54 ? 338 ASN A O   1 
ATOM 3179 C CB  . ASN B 2 337 ? 142.953 101.911 172.300 1.00 112.11 ? 338 ASN A CB  1 
ATOM 3180 C CG  . ASN B 2 337 ? 141.440 101.921 172.240 1.00 112.75 ? 338 ASN A CG  1 
ATOM 3181 O OD1 . ASN B 2 337 ? 140.839 102.791 171.612 1.00 108.82 ? 338 ASN A OD1 1 
ATOM 3182 N ND2 . ASN B 2 337 ? 140.816 100.949 172.893 1.00 111.31 ? 338 ASN A ND2 1 
ATOM 3183 N N   . LEU B 2 338 ? 142.788 102.922 168.867 1.00 92.96  ? 339 LEU A N   1 
ATOM 3184 C CA  . LEU B 2 338 ? 142.480 102.392 167.542 1.00 92.77  ? 339 LEU A CA  1 
ATOM 3185 C C   . LEU B 2 338 ? 143.728 101.837 166.870 1.00 96.04  ? 339 LEU A C   1 
ATOM 3186 O O   . LEU B 2 338 ? 143.690 100.763 166.259 1.00 107.84 ? 339 LEU A O   1 
ATOM 3187 C CB  . LEU B 2 338 ? 141.847 103.480 166.677 1.00 94.28  ? 339 LEU A CB  1 
ATOM 3188 C CG  . LEU B 2 338 ? 141.994 103.321 165.162 1.00 85.46  ? 339 LEU A CG  1 
ATOM 3189 C CD1 . LEU B 2 338 ? 141.043 102.262 164.639 1.00 92.53  ? 339 LEU A CD1 1 
ATOM 3190 C CD2 . LEU B 2 338 ? 141.763 104.643 164.455 1.00 86.85  ? 339 LEU A CD2 1 
ATOM 3191 N N   . CYS B 2 339 ? 144.845 102.558 166.973 1.00 109.76 ? 340 CYS A N   1 
ATOM 3192 C CA  . CYS B 2 339 ? 146.090 102.089 166.376 1.00 113.47 ? 340 CYS A CA  1 
ATOM 3193 C C   . CYS B 2 339 ? 146.608 100.835 167.071 1.00 113.20 ? 340 CYS A C   1 
ATOM 3194 O O   . CYS B 2 339 ? 147.122 99.924  166.414 1.00 115.74 ? 340 CYS A O   1 
ATOM 3195 C CB  . CYS B 2 339 ? 147.134 103.203 166.423 1.00 117.12 ? 340 CYS A CB  1 
ATOM 3196 S SG  . CYS B 2 339 ? 147.990 103.344 168.007 1.00 139.20 ? 340 CYS A SG  1 
ATOM 3197 N N   . GLN B 2 340 ? 146.481 100.769 168.396 1.00 104.07 ? 341 GLN A N   1 
ATOM 3198 C CA  . GLN B 2 340 ? 147.042 99.654  169.148 1.00 104.81 ? 341 GLN A CA  1 
ATOM 3199 C C   . GLN B 2 340 ? 146.206 98.385  169.057 1.00 106.61 ? 341 GLN A C   1 
ATOM 3200 O O   . GLN B 2 340 ? 146.708 97.308  169.397 1.00 111.23 ? 341 GLN A O   1 
ATOM 3201 C CB  . GLN B 2 340 ? 147.213 100.048 170.616 1.00 109.89 ? 341 GLN A CB  1 
ATOM 3202 C CG  . GLN B 2 340 ? 148.324 101.053 170.859 1.00 112.04 ? 341 GLN A CG  1 
ATOM 3203 C CD  . GLN B 2 340 ? 148.243 101.688 172.231 1.00 115.61 ? 341 GLN A CD  1 
ATOM 3204 O OE1 . GLN B 2 340 ? 147.172 101.757 172.833 1.00 115.05 ? 341 GLN A OE1 1 
ATOM 3205 N NE2 . GLN B 2 340 ? 149.379 102.155 172.735 1.00 114.68 ? 341 GLN A NE2 1 
ATOM 3206 N N   . GLU B 2 341 ? 144.953 98.478  168.615 1.00 103.38 ? 342 GLU A N   1 
ATOM 3207 C CA  . GLU B 2 341 ? 144.090 97.302  168.535 1.00 102.59 ? 342 GLU A CA  1 
ATOM 3208 C C   . GLU B 2 341 ? 144.118 96.672  167.145 1.00 104.83 ? 342 GLU A C   1 
ATOM 3209 O O   . GLU B 2 341 ? 144.452 95.493  166.998 1.00 112.19 ? 342 GLU A O   1 
ATOM 3210 C CB  . GLU B 2 341 ? 142.657 97.672  168.932 1.00 104.78 ? 342 GLU A CB  1 
ATOM 3211 C CG  . GLU B 2 341 ? 142.401 97.607  170.426 1.00 110.06 ? 342 GLU A CG  1 
ATOM 3212 C CD  . GLU B 2 341 ? 140.931 97.460  170.759 1.00 116.05 ? 342 GLU A CD  1 
ATOM 3213 O OE1 . GLU B 2 341 ? 140.105 97.462  169.824 1.00 116.16 ? 342 GLU A OE1 1 
ATOM 3214 O OE2 . GLU B 2 341 ? 140.603 97.342  171.958 1.00 115.98 ? 342 GLU A OE2 1 
ATOM 3215 N N   . GLN B 2 342 ? 143.744 97.470  166.133 1.00 89.40  ? 343 GLN A N   1 
ATOM 3216 C CA  . GLN B 2 342 ? 143.733 97.022  164.718 1.00 90.17  ? 343 GLN A CA  1 
ATOM 3217 C C   . GLN B 2 342 ? 145.188 96.845  164.253 1.00 95.30  ? 343 GLN A C   1 
ATOM 3218 O O   . GLN B 2 342 ? 145.776 97.834  163.771 1.00 98.73  ? 343 GLN A O   1 
ATOM 3219 C CB  . GLN B 2 342 ? 143.040 98.061  163.826 1.00 94.08  ? 343 GLN A CB  1 
ATOM 3220 C CG  . GLN B 2 342 ? 141.682 98.538  164.322 1.00 101.54 ? 343 GLN A CG  1 
ATOM 3221 C CD  . GLN B 2 342 ? 140.807 97.415  164.820 1.00 99.96  ? 343 GLN A CD  1 
ATOM 3222 O OE1 . GLN B 2 342 ? 140.436 96.506  164.072 1.00 100.98 ? 343 GLN A OE1 1 
ATOM 3223 N NE2 . GLN B 2 342 ? 140.497 97.468  166.106 1.00 95.68  ? 343 GLN A NE2 1 
ATOM 3224 N N   . LYS B 2 343 ? 145.770 95.653  164.401 1.00 107.17 ? 344 LYS A N   1 
ATOM 3225 C CA  . LYS B 2 343 ? 147.149 95.453  163.969 1.00 106.20 ? 344 LYS A CA  1 
ATOM 3226 C C   . LYS B 2 343 ? 147.255 95.411  162.450 1.00 108.58 ? 344 LYS A C   1 
ATOM 3227 O O   . LYS B 2 343 ? 148.229 95.910  161.877 1.00 113.98 ? 344 LYS A O   1 
ATOM 3228 C CB  . LYS B 2 343 ? 147.709 94.168  164.578 1.00 104.91 ? 344 LYS A CB  1 
ATOM 3229 C CG  . LYS B 2 343 ? 147.216 93.876  165.983 1.00 105.40 ? 344 LYS A CG  1 
ATOM 3230 C CD  . LYS B 2 343 ? 147.760 94.886  166.979 1.00 107.09 ? 344 LYS A CD  1 
ATOM 3231 C CE  . LYS B 2 343 ? 149.275 94.813  167.066 1.00 109.19 ? 344 LYS A CE  1 
ATOM 3232 N NZ  . LYS B 2 343 ? 149.783 95.402  168.335 1.00 107.71 ? 344 LYS A NZ  1 
ATOM 3233 N N   . MET B 2 344 ? 146.264 94.824  161.781 1.00 95.33  ? 345 MET A N   1 
ATOM 3234 C CA  . MET B 2 344 ? 146.304 94.623  160.341 1.00 89.18  ? 345 MET A CA  1 
ATOM 3235 C C   . MET B 2 344 ? 145.629 95.747  159.566 1.00 90.23  ? 345 MET A C   1 
ATOM 3236 O O   . MET B 2 344 ? 145.278 95.553  158.397 1.00 92.31  ? 345 MET A O   1 
ATOM 3237 C CB  . MET B 2 344 ? 145.659 93.285  159.980 1.00 95.30  ? 345 MET A CB  1 
ATOM 3238 C CG  . MET B 2 344 ? 145.953 92.173  160.968 1.00 101.26 ? 345 MET A CG  1 
ATOM 3239 S SD  . MET B 2 344 ? 145.371 90.567  160.396 1.00 126.55 ? 345 MET A SD  1 
ATOM 3240 C CE  . MET B 2 344 ? 145.672 89.566  161.850 1.00 102.43 ? 345 MET A CE  1 
ATOM 3241 N N   . LEU B 2 345 ? 145.435 96.907  160.184 1.00 78.33  ? 346 LEU A N   1 
ATOM 3242 C CA  . LEU B 2 345 ? 144.786 98.014  159.497 1.00 81.47  ? 346 LEU A CA  1 
ATOM 3243 C C   . LEU B 2 345 ? 145.648 98.500  158.338 1.00 81.71  ? 346 LEU A C   1 
ATOM 3244 O O   . LEU B 2 345 ? 146.862 98.670  158.472 1.00 87.02  ? 346 LEU A O   1 
ATOM 3245 C CB  . LEU B 2 345 ? 144.515 99.159  160.470 1.00 73.41  ? 346 LEU A CB  1 
ATOM 3246 C CG  . LEU B 2 345 ? 143.584 100.260 159.965 1.00 73.73  ? 346 LEU A CG  1 
ATOM 3247 C CD1 . LEU B 2 345 ? 142.341 99.660  159.342 1.00 75.80  ? 346 LEU A CD1 1 
ATOM 3248 C CD2 . LEU B 2 345 ? 143.211 101.195 161.096 1.00 77.41  ? 346 LEU A CD2 1 
ATOM 3249 N N   . ARG B 2 346 ? 145.011 98.720  157.195 1.00 78.66  ? 347 ARG A N   1 
ATOM 3250 C CA  . ARG B 2 346 ? 145.696 99.139  155.980 1.00 71.63  ? 347 ARG A CA  1 
ATOM 3251 C C   . ARG B 2 346 ? 145.209 100.474 155.446 1.00 77.07  ? 347 ARG A C   1 
ATOM 3252 O O   . ARG B 2 346 ? 146.022 101.288 155.002 1.00 81.45  ? 347 ARG A O   1 
ATOM 3253 C CB  . ARG B 2 346 ? 145.537 98.061  154.898 1.00 82.58  ? 347 ARG A CB  1 
ATOM 3254 C CG  . ARG B 2 346 ? 145.652 98.565  153.470 1.00 86.03  ? 347 ARG A CG  1 
ATOM 3255 C CD  . ARG B 2 346 ? 145.881 97.418  152.501 1.00 81.81  ? 347 ARG A CD  1 
ATOM 3256 N NE  . ARG B 2 346 ? 146.770 96.408  153.062 1.00 87.51  ? 347 ARG A NE  1 
ATOM 3257 C CZ  . ARG B 2 346 ? 146.410 95.164  153.344 1.00 91.93  ? 347 ARG A CZ  1 
ATOM 3258 N NH1 . ARG B 2 346 ? 145.178 94.735  153.126 1.00 88.76  ? 347 ARG A NH1 1 
ATOM 3259 N NH2 . ARG B 2 346 ? 147.307 94.330  153.861 1.00 89.96  ? 347 ARG A NH2 1 
ATOM 3260 N N   . THR B 2 347 ? 143.904 100.725 155.480 1.00 75.79  ? 348 THR A N   1 
ATOM 3261 C CA  . THR B 2 347 ? 143.331 101.981 155.025 1.00 68.54  ? 348 THR A CA  1 
ATOM 3262 C C   . THR B 2 347 ? 142.485 102.575 156.142 1.00 74.94  ? 348 THR A C   1 
ATOM 3263 O O   . THR B 2 347 ? 141.885 101.849 156.938 1.00 89.71  ? 348 THR A O   1 
ATOM 3264 C CB  . THR B 2 347 ? 142.479 101.782 153.763 1.00 70.54  ? 348 THR A CB  1 
ATOM 3265 O OG1 . THR B 2 347 ? 143.213 101.000 152.814 1.00 80.44  ? 348 THR A OG1 1 
ATOM 3266 C CG2 . THR B 2 347 ? 142.127 103.117 153.132 1.00 72.15  ? 348 THR A CG2 1 
ATOM 3267 N N   . LEU B 2 348 ? 142.450 103.904 156.202 1.00 58.06  ? 349 LEU A N   1 
ATOM 3268 C CA  . LEU B 2 348 ? 141.696 104.617 157.229 1.00 50.98  ? 349 LEU A CA  1 
ATOM 3269 C C   . LEU B 2 348 ? 141.125 105.881 156.608 1.00 56.02  ? 349 LEU A C   1 
ATOM 3270 O O   . LEU B 2 348 ? 141.863 106.836 156.351 1.00 65.81  ? 349 LEU A O   1 
ATOM 3271 C CB  . LEU B 2 348 ? 142.577 104.951 158.430 1.00 50.15  ? 349 LEU A CB  1 
ATOM 3272 C CG  . LEU B 2 348 ? 141.866 105.540 159.646 1.00 53.27  ? 349 LEU A CG  1 
ATOM 3273 C CD1 . LEU B 2 348 ? 140.996 104.492 160.312 1.00 62.70  ? 349 LEU A CD1 1 
ATOM 3274 C CD2 . LEU B 2 348 ? 142.876 106.098 160.630 1.00 61.43  ? 349 LEU A CD2 1 
ATOM 3275 N N   . ASP B 2 349 ? 139.819 105.886 156.368 1.00 68.26  ? 350 ASP A N   1 
ATOM 3276 C CA  . ASP B 2 349 ? 139.115 107.037 155.817 1.00 60.15  ? 350 ASP A CA  1 
ATOM 3277 C C   . ASP B 2 349 ? 138.215 107.615 156.899 1.00 60.83  ? 350 ASP A C   1 
ATOM 3278 O O   . ASP B 2 349 ? 137.286 106.946 157.360 1.00 78.22  ? 350 ASP A O   1 
ATOM 3279 C CB  . ASP B 2 349 ? 138.299 106.640 154.588 1.00 61.58  ? 350 ASP A CB  1 
ATOM 3280 C CG  . ASP B 2 349 ? 138.016 107.812 153.674 1.00 75.43  ? 350 ASP A CG  1 
ATOM 3281 O OD1 . ASP B 2 349 ? 137.647 108.889 154.184 1.00 81.23  ? 350 ASP A OD1 1 
ATOM 3282 O OD2 . ASP B 2 349 ? 138.158 107.654 152.445 1.00 79.14  ? 350 ASP A OD2 1 
ATOM 3283 N N   . LEU B 2 350 ? 138.490 108.851 157.299 1.00 50.47  ? 351 LEU A N   1 
ATOM 3284 C CA  . LEU B 2 350 ? 137.733 109.537 158.337 1.00 49.71  ? 351 LEU A CA  1 
ATOM 3285 C C   . LEU B 2 350 ? 137.405 110.955 157.901 1.00 63.81  ? 351 LEU A C   1 
ATOM 3286 O O   . LEU B 2 350 ? 137.454 111.899 158.693 1.00 74.21  ? 351 LEU A O   1 
ATOM 3287 C CB  . LEU B 2 350 ? 138.496 109.537 159.658 1.00 42.65  ? 351 LEU A CB  1 
ATOM 3288 C CG  . LEU B 2 350 ? 138.665 108.171 160.320 1.00 46.16  ? 351 LEU A CG  1 
ATOM 3289 C CD1 . LEU B 2 350 ? 139.489 108.284 161.588 1.00 54.31  ? 351 LEU A CD1 1 
ATOM 3290 C CD2 . LEU B 2 350 ? 137.311 107.554 160.614 1.00 54.73  ? 351 LEU A CD2 1 
ATOM 3291 N N   . SER B 2 351 ? 137.064 111.121 156.628 1.00 63.14  ? 352 SER A N   1 
ATOM 3292 C CA  . SER B 2 351 ? 136.763 112.430 156.078 1.00 65.08  ? 352 SER A CA  1 
ATOM 3293 C C   . SER B 2 351 ? 135.314 112.821 156.367 1.00 77.25  ? 352 SER A C   1 
ATOM 3294 O O   . SER B 2 351 ? 134.501 112.017 156.829 1.00 83.15  ? 352 SER A O   1 
ATOM 3295 C CB  . SER B 2 351 ? 137.027 112.443 154.574 1.00 68.46  ? 352 SER A CB  1 
ATOM 3296 O OG  . SER B 2 351 ? 136.398 111.347 153.937 1.00 74.60  ? 352 SER A OG  1 
ATOM 3297 N N   . TYR B 2 352 ? 135.005 114.091 156.094 1.00 82.98  ? 353 TYR A N   1 
ATOM 3298 C CA  . TYR B 2 352 ? 133.641 114.618 156.176 1.00 74.36  ? 353 TYR A CA  1 
ATOM 3299 C C   . TYR B 2 352 ? 133.067 114.509 157.586 1.00 77.52  ? 353 TYR A C   1 
ATOM 3300 O O   . TYR B 2 352 ? 131.869 114.294 157.771 1.00 91.48  ? 353 TYR A O   1 
ATOM 3301 C CB  . TYR B 2 352 ? 132.724 113.924 155.170 1.00 81.31  ? 353 TYR A CB  1 
ATOM 3302 C CG  . TYR B 2 352 ? 133.009 114.286 153.737 1.00 87.25  ? 353 TYR A CG  1 
ATOM 3303 C CD1 . TYR B 2 352 ? 132.520 115.461 153.189 1.00 88.29  ? 353 TYR A CD1 1 
ATOM 3304 C CD2 . TYR B 2 352 ? 133.774 113.455 152.932 1.00 90.39  ? 353 TYR A CD2 1 
ATOM 3305 C CE1 . TYR B 2 352 ? 132.776 115.794 151.876 1.00 93.45  ? 353 TYR A CE1 1 
ATOM 3306 C CE2 . TYR B 2 352 ? 134.038 113.780 151.619 1.00 93.55  ? 353 TYR A CE2 1 
ATOM 3307 C CZ  . TYR B 2 352 ? 133.538 114.952 151.097 1.00 98.55  ? 353 TYR A CZ  1 
ATOM 3308 O OH  . TYR B 2 352 ? 133.799 115.283 149.787 1.00 101.70 ? 353 TYR A OH  1 
ATOM 3309 N N   . ASN B 2 353 ? 133.922 114.667 158.591 1.00 70.88  ? 354 ASN A N   1 
ATOM 3310 C CA  . ASN B 2 353 ? 133.473 114.617 159.976 1.00 72.68  ? 354 ASN A CA  1 
ATOM 3311 C C   . ASN B 2 353 ? 133.894 115.877 160.718 1.00 82.12  ? 354 ASN A C   1 
ATOM 3312 O O   . ASN B 2 353 ? 134.374 116.834 160.103 1.00 88.56  ? 354 ASN A O   1 
ATOM 3313 C CB  . ASN B 2 353 ? 134.023 113.378 160.682 1.00 71.73  ? 354 ASN A CB  1 
ATOM 3314 C CG  . ASN B 2 353 ? 133.787 112.107 159.898 1.00 72.63  ? 354 ASN A CG  1 
ATOM 3315 O OD1 . ASN B 2 353 ? 132.818 111.995 159.152 1.00 81.68  ? 354 ASN A OD1 1 
ATOM 3316 N ND2 . ASN B 2 353 ? 134.677 111.138 160.064 1.00 80.35  ? 354 ASN A ND2 1 
ATOM 3317 N N   . ASN B 2 354 ? 133.710 115.892 162.037 1.00 93.57  ? 355 ASN A N   1 
ATOM 3318 C CA  . ASN B 2 354 ? 134.074 117.032 162.867 1.00 92.53  ? 355 ASN A CA  1 
ATOM 3319 C C   . ASN B 2 354 ? 135.309 116.747 163.716 1.00 97.21  ? 355 ASN A C   1 
ATOM 3320 O O   . ASN B 2 354 ? 135.450 117.287 164.815 1.00 102.86 ? 355 ASN A O   1 
ATOM 3321 C CB  . ASN B 2 354 ? 132.906 117.442 163.761 1.00 96.49  ? 355 ASN A CB  1 
ATOM 3322 C CG  . ASN B 2 354 ? 131.647 117.735 162.975 1.00 100.24 ? 355 ASN A CG  1 
ATOM 3323 O OD1 . ASN B 2 354 ? 131.687 117.905 161.758 1.00 102.76 ? 355 ASN A OD1 1 
ATOM 3324 N ND2 . ASN B 2 354 ? 130.519 117.800 163.671 1.00 94.47  ? 355 ASN A ND2 1 
ATOM 3325 N N   . ILE B 2 355 ? 136.200 115.875 163.229 1.00 90.96  ? 356 ILE A N   1 
ATOM 3326 C CA  . ILE B 2 355 ? 137.449 115.521 163.969 1.00 83.52  ? 356 ILE A CA  1 
ATOM 3327 C C   . ILE B 2 355 ? 138.373 116.744 163.955 1.00 85.06  ? 356 ILE A C   1 
ATOM 3328 O O   . ILE B 2 355 ? 138.689 117.188 162.858 1.00 91.01  ? 356 ILE A O   1 
ATOM 3329 C CB  . ILE B 2 355 ? 138.120 114.280 163.355 1.00 85.66  ? 356 ILE A CB  1 
ATOM 3330 C CG1 . ILE B 2 355 ? 137.398 113.003 163.769 1.00 85.42  ? 356 ILE A CG1 1 
ATOM 3331 C CG2 . ILE B 2 355 ? 139.610 114.217 163.698 1.00 93.57  ? 356 ILE A CG2 1 
ATOM 3332 C CD1 . ILE B 2 355 ? 137.022 112.106 162.605 1.00 83.02  ? 356 ILE A CD1 1 
ATOM 3333 N N   . ARG B 2 356 ? 138.824 117.226 165.114 1.00 91.21  ? 357 ARG A N   1 
ATOM 3334 C CA  . ARG B 2 356 ? 139.685 118.391 165.237 1.00 97.00  ? 357 ARG A CA  1 
ATOM 3335 C C   . ARG B 2 356 ? 140.987 118.066 165.949 1.00 100.39 ? 357 ARG A C   1 
ATOM 3336 O O   . ARG B 2 356 ? 141.949 118.826 165.806 1.00 103.56 ? 357 ARG A O   1 
ATOM 3337 C CB  . ARG B 2 356 ? 138.966 119.512 166.004 1.00 93.47  ? 357 ARG A CB  1 
ATOM 3338 C CG  . ARG B 2 356 ? 138.635 119.172 167.443 1.00 95.88  ? 357 ARG A CG  1 
ATOM 3339 C CD  . ARG B 2 356 ? 138.015 120.364 168.148 1.00 104.43 ? 357 ARG A CD  1 
ATOM 3340 N NE  . ARG B 2 356 ? 138.490 121.628 167.597 1.00 110.57 ? 357 ARG A NE  1 
ATOM 3341 C CZ  . ARG B 2 356 ? 139.420 122.388 168.158 1.00 109.90 ? 357 ARG A CZ  1 
ATOM 3342 N NH1 . ARG B 2 356 ? 139.995 122.048 169.300 1.00 104.94 ? 357 ARG A NH1 1 
ATOM 3343 N NH2 . ARG B 2 356 ? 139.782 123.519 167.559 1.00 105.22 ? 357 ARG A NH2 1 
ATOM 3344 N N   . ASP B 2 357 ? 141.063 116.953 166.681 1.00 103.49 ? 358 ASP A N   1 
ATOM 3345 C CA  . ASP B 2 357 ? 142.282 116.559 167.436 1.00 103.07 ? 358 ASP A CA  1 
ATOM 3346 C C   . ASP B 2 357 ? 142.645 115.138 167.013 1.00 104.64 ? 358 ASP A C   1 
ATOM 3347 O O   . ASP B 2 357 ? 141.735 114.282 167.089 1.00 108.15 ? 358 ASP A O   1 
ATOM 3348 C CB  . ASP B 2 357 ? 142.058 116.697 168.931 1.00 104.79 ? 358 ASP A CB  1 
ATOM 3349 C CG  . ASP B 2 357 ? 140.808 116.017 169.469 1.00 112.14 ? 358 ASP A CG  1 
ATOM 3350 O OD1 . ASP B 2 357 ? 139.713 116.599 169.323 1.00 115.92 ? 358 ASP A OD1 1 
ATOM 3351 O OD2 . ASP B 2 357 ? 140.939 114.905 170.021 1.00 111.01 ? 358 ASP A OD2 1 
ATOM 3352 N N   . LEU B 2 358 ? 143.893 114.885 166.589 1.00 87.12  ? 359 LEU A N   1 
ATOM 3353 C CA  . LEU B 2 358 ? 144.243 113.570 166.085 1.00 85.33  ? 359 LEU A CA  1 
ATOM 3354 C C   . LEU B 2 358 ? 144.949 112.762 167.167 1.00 88.79  ? 359 LEU A C   1 
ATOM 3355 O O   . LEU B 2 358 ? 145.714 113.310 167.965 1.00 86.99  ? 359 LEU A O   1 
ATOM 3356 C CB  . LEU B 2 358 ? 145.129 113.624 164.838 1.00 79.62  ? 359 LEU A CB  1 
ATOM 3357 C CG  . LEU B 2 358 ? 144.578 114.431 163.665 1.00 81.02  ? 359 LEU A CG  1 
ATOM 3358 C CD1 . LEU B 2 358 ? 145.654 114.646 162.619 1.00 84.83  ? 359 LEU A CD1 1 
ATOM 3359 C CD2 . LEU B 2 358 ? 143.375 113.733 163.064 1.00 78.77  ? 359 LEU A CD2 1 
ATOM 3360 N N   . PRO B 2 359 ? 144.707 111.453 167.210 1.00 94.74  ? 360 PRO A N   1 
ATOM 3361 C CA  . PRO B 2 359 ? 145.437 110.597 168.151 1.00 93.68  ? 360 PRO A CA  1 
ATOM 3362 C C   . PRO B 2 359 ? 146.843 110.298 167.663 1.00 94.93  ? 360 PRO A C   1 
ATOM 3363 O O   . PRO B 2 359 ? 147.280 110.844 166.646 1.00 102.50 ? 360 PRO A O   1 
ATOM 3364 C CB  . PRO B 2 359 ? 144.576 109.331 168.203 1.00 92.70  ? 360 PRO A CB  1 
ATOM 3365 C CG  . PRO B 2 359 ? 143.968 109.261 166.844 1.00 92.98  ? 360 PRO A CG  1 
ATOM 3366 C CD  . PRO B 2 359 ? 143.738 110.688 166.405 1.00 91.49  ? 360 PRO A CD  1 
ATOM 3367 N N   . SER B 2 360 ? 147.564 109.443 168.379 1.00 87.31  ? 361 SER A N   1 
ATOM 3368 C CA  . SER B 2 360 ? 148.889 109.018 167.954 1.00 85.79  ? 361 SER A CA  1 
ATOM 3369 C C   . SER B 2 360 ? 148.773 107.720 167.167 1.00 89.27  ? 361 SER A C   1 
ATOM 3370 O O   . SER B 2 360 ? 148.218 106.733 167.661 1.00 89.22  ? 361 SER A O   1 
ATOM 3371 C CB  . SER B 2 360 ? 149.813 108.834 169.158 1.00 91.83  ? 361 SER A CB  1 
ATOM 3372 O OG  . SER B 2 360 ? 151.172 108.822 168.758 1.00 97.89  ? 361 SER A OG  1 
ATOM 3373 N N   . PHE B 2 361 ? 149.302 107.724 165.947 1.00 86.55  ? 362 PHE A N   1 
ATOM 3374 C CA  . PHE B 2 361 ? 149.189 106.600 165.031 1.00 80.16  ? 362 PHE A CA  1 
ATOM 3375 C C   . PHE B 2 361 ? 150.355 105.626 165.141 1.00 91.84  ? 362 PHE A C   1 
ATOM 3376 O O   . PHE B 2 361 ? 150.454 104.705 164.324 1.00 96.39  ? 362 PHE A O   1 
ATOM 3377 C CB  . PHE B 2 361 ? 149.084 107.108 163.592 1.00 78.82  ? 362 PHE A CB  1 
ATOM 3378 C CG  . PHE B 2 361 ? 147.764 107.737 163.262 1.00 77.58  ? 362 PHE A CG  1 
ATOM 3379 C CD1 . PHE B 2 361 ? 146.620 106.970 163.156 1.00 82.78  ? 362 PHE A CD1 1 
ATOM 3380 C CD2 . PHE B 2 361 ? 147.671 109.099 163.044 1.00 82.10  ? 362 PHE A CD2 1 
ATOM 3381 C CE1 . PHE B 2 361 ? 145.406 107.552 162.847 1.00 81.82  ? 362 PHE A CE1 1 
ATOM 3382 C CE2 . PHE B 2 361 ? 146.461 109.685 162.735 1.00 83.97  ? 362 PHE A CE2 1 
ATOM 3383 C CZ  . PHE B 2 361 ? 145.328 108.910 162.637 1.00 79.74  ? 362 PHE A CZ  1 
ATOM 3384 N N   . ASN B 2 362 ? 151.232 105.804 166.132 1.00 101.56 ? 363 ASN A N   1 
ATOM 3385 C CA  . ASN B 2 362 ? 152.483 105.051 166.176 1.00 98.83  ? 363 ASN A CA  1 
ATOM 3386 C C   . ASN B 2 362 ? 152.258 103.547 166.275 1.00 104.20 ? 363 ASN A C   1 
ATOM 3387 O O   . ASN B 2 362 ? 153.140 102.766 165.900 1.00 108.02 ? 363 ASN A O   1 
ATOM 3388 C CB  . ASN B 2 362 ? 153.337 105.533 167.349 1.00 98.38  ? 363 ASN A CB  1 
ATOM 3389 C CG  . ASN B 2 362 ? 152.552 105.621 168.643 1.00 99.33  ? 363 ASN A CG  1 
ATOM 3390 O OD1 . ASN B 2 362 ? 151.591 104.882 168.854 1.00 97.12  ? 363 ASN A OD1 1 
ATOM 3391 N ND2 . ASN B 2 362 ? 152.961 106.530 169.520 1.00 96.25  ? 363 ASN A ND2 1 
ATOM 3392 N N   . GLY B 2 363 ? 151.100 103.121 166.778 1.00 104.08 ? 364 GLY A N   1 
ATOM 3393 C CA  . GLY B 2 363 ? 150.875 101.698 166.976 1.00 103.11 ? 364 GLY A CA  1 
ATOM 3394 C C   . GLY B 2 363 ? 150.811 100.909 165.682 1.00 105.68 ? 364 GLY A C   1 
ATOM 3395 O O   . GLY B 2 363 ? 151.406 99.834  165.572 1.00 108.44 ? 364 GLY A O   1 
ATOM 3396 N N   . CYS B 2 364 ? 150.098 101.427 164.685 1.00 108.64 ? 365 CYS A N   1 
ATOM 3397 C CA  . CYS B 2 364 ? 149.852 100.672 163.464 1.00 108.86 ? 365 CYS A CA  1 
ATOM 3398 C C   . CYS B 2 364 ? 151.028 100.802 162.506 1.00 103.23 ? 365 CYS A C   1 
ATOM 3399 O O   . CYS B 2 364 ? 151.486 101.911 162.215 1.00 105.18 ? 365 CYS A O   1 
ATOM 3400 C CB  . CYS B 2 364 ? 148.564 101.147 162.792 1.00 111.62 ? 365 CYS A CB  1 
ATOM 3401 S SG  . CYS B 2 364 ? 148.274 102.925 162.881 1.00 125.27 ? 365 CYS A SG  1 
ATOM 3402 N N   . HIS B 2 365 ? 151.514 99.662  162.017 1.00 99.78  ? 366 HIS A N   1 
ATOM 3403 C CA  . HIS B 2 365 ? 152.627 99.619  161.079 1.00 105.71 ? 366 HIS A CA  1 
ATOM 3404 C C   . HIS B 2 365 ? 152.208 99.340  159.646 1.00 108.94 ? 366 HIS A C   1 
ATOM 3405 O O   . HIS B 2 365 ? 152.869 99.814  158.722 1.00 108.92 ? 366 HIS A O   1 
ATOM 3406 C CB  . HIS B 2 365 ? 153.644 98.553  161.506 1.00 103.28 ? 366 HIS A CB  1 
ATOM 3407 C CG  . HIS B 2 365 ? 154.143 98.723  162.905 1.00 109.08 ? 366 HIS A CG  1 
ATOM 3408 N ND1 . HIS B 2 365 ? 154.781 99.867  163.334 1.00 109.92 ? 366 HIS A ND1 1 
ATOM 3409 C CD2 . HIS B 2 365 ? 154.097 97.894  163.975 1.00 110.61 ? 366 HIS A CD2 1 
ATOM 3410 C CE1 . HIS B 2 365 ? 155.107 99.736  164.607 1.00 107.93 ? 366 HIS A CE1 1 
ATOM 3411 N NE2 . HIS B 2 365 ? 154.703 98.548  165.020 1.00 112.56 ? 366 HIS A NE2 1 
ATOM 3412 N N   . ALA B 2 366 ? 151.133 98.586  159.438 1.00 85.86  ? 367 ALA A N   1 
ATOM 3413 C CA  . ALA B 2 366 ? 150.681 98.252  158.095 1.00 79.53  ? 367 ALA A CA  1 
ATOM 3414 C C   . ALA B 2 366 ? 149.810 99.334  157.476 1.00 81.81  ? 367 ALA A C   1 
ATOM 3415 O O   . ALA B 2 366 ? 149.372 99.173  156.333 1.00 86.60  ? 367 ALA A O   1 
ATOM 3416 C CB  . ALA B 2 366 ? 149.920 96.926  158.110 1.00 81.08  ? 367 ALA A CB  1 
ATOM 3417 N N   . LEU B 2 367 ? 149.542 100.418 158.198 1.00 76.28  ? 368 LEU A N   1 
ATOM 3418 C CA  . LEU B 2 367 ? 148.710 101.490 157.668 1.00 76.75  ? 368 LEU A CA  1 
ATOM 3419 C C   . LEU B 2 367 ? 149.404 102.157 156.489 1.00 69.28  ? 368 LEU A C   1 
ATOM 3420 O O   . LEU B 2 367 ? 150.531 102.644 156.615 1.00 72.01  ? 368 LEU A O   1 
ATOM 3421 C CB  . LEU B 2 367 ? 148.415 102.508 158.767 1.00 73.73  ? 368 LEU A CB  1 
ATOM 3422 C CG  . LEU B 2 367 ? 147.397 103.606 158.461 1.00 72.92  ? 368 LEU A CG  1 
ATOM 3423 C CD1 . LEU B 2 367 ? 146.202 103.035 157.729 1.00 76.88  ? 368 LEU A CD1 1 
ATOM 3424 C CD2 . LEU B 2 367 ? 146.958 104.283 159.743 1.00 73.26  ? 368 LEU A CD2 1 
ATOM 3425 N N   . GLU B 2 368 ? 148.739 102.197 155.317 1.00 73.45  ? 369 GLU A N   1 
ATOM 3426 C CA  . GLU B 2 368 ? 149.342 102.712 154.053 1.00 69.52  ? 369 GLU A CA  1 
ATOM 3427 C C   . GLU B 2 368 ? 148.578 103.900 153.455 1.00 75.60  ? 369 GLU A C   1 
ATOM 3428 O O   . GLU B 2 368 ? 149.089 104.441 152.473 1.00 86.05  ? 369 GLU A O   1 
ATOM 3429 C CB  . GLU B 2 368 ? 149.325 101.664 152.942 1.00 78.28  ? 369 GLU A CB  1 
ATOM 3430 C CG  . GLU B 2 368 ? 149.316 100.222 153.437 1.00 91.43  ? 369 GLU A CG  1 
ATOM 3431 C CD  . GLU B 2 368 ? 149.389 99.182  152.336 1.00 93.37  ? 369 GLU A CD  1 
ATOM 3432 O OE1 . GLU B 2 368 ? 148.861 99.434  151.233 1.00 90.10  ? 369 GLU A OE1 1 
ATOM 3433 O OE2 . GLU B 2 368 ? 149.974 98.111  152.593 1.00 92.06  ? 369 GLU A OE2 1 
ATOM 3434 N N   . GLU B 2 369 ? 147.340 104.178 153.858 1.00 76.18  ? 370 GLU A N   1 
ATOM 3435 C CA  . GLU B 2 369 ? 146.624 105.370 153.434 1.00 70.34  ? 370 GLU A CA  1 
ATOM 3436 C C   . GLU B 2 369 ? 145.864 105.956 154.612 1.00 78.11  ? 370 GLU A C   1 
ATOM 3437 O O   . GLU B 2 369 ? 145.275 105.221 155.409 1.00 95.35  ? 370 GLU A O   1 
ATOM 3438 C CB  . GLU B 2 369 ? 145.651 105.058 152.298 1.00 73.72  ? 370 GLU A CB  1 
ATOM 3439 C CG  . GLU B 2 369 ? 146.319 104.586 151.026 1.00 83.33  ? 370 GLU A CG  1 
ATOM 3440 C CD  . GLU B 2 369 ? 145.388 104.637 149.835 1.00 94.97  ? 370 GLU A CD  1 
ATOM 3441 O OE1 . GLU B 2 369 ? 144.622 105.617 149.721 1.00 95.32  ? 370 GLU A OE1 1 
ATOM 3442 O OE2 . GLU B 2 369 ? 145.419 103.698 149.013 1.00 101.58 ? 370 GLU A OE2 1 
ATOM 3443 N N   . ILE B 2 370 ? 145.887 107.280 154.722 1.00 56.62  ? 371 ILE A N   1 
ATOM 3444 C CA  . ILE B 2 370 ? 145.146 108.003 155.747 1.00 48.52  ? 371 ILE A CA  1 
ATOM 3445 C C   . ILE B 2 370 ? 144.463 109.186 155.083 1.00 54.58  ? 371 ILE A C   1 
ATOM 3446 O O   . ILE B 2 370 ? 145.116 109.980 154.400 1.00 66.07  ? 371 ILE A O   1 
ATOM 3447 C CB  . ILE B 2 370 ? 146.059 108.480 156.891 1.00 50.34  ? 371 ILE A CB  1 
ATOM 3448 C CG1 . ILE B 2 370 ? 146.730 107.293 157.575 1.00 53.46  ? 371 ILE A CG1 1 
ATOM 3449 C CG2 . ILE B 2 370 ? 145.264 109.272 157.902 1.00 59.10  ? 371 ILE A CG2 1 
ATOM 3450 C CD1 . ILE B 2 370 ? 147.762 107.691 158.597 1.00 66.65  ? 371 ILE A CD1 1 
ATOM 3451 N N   . SER B 2 371 ? 143.152 109.301 155.276 1.00 60.41  ? 372 SER A N   1 
ATOM 3452 C CA  . SER B 2 371 ? 142.374 110.406 154.734 1.00 55.23  ? 372 SER A CA  1 
ATOM 3453 C C   . SER B 2 371 ? 141.717 111.153 155.882 1.00 55.34  ? 372 SER A C   1 
ATOM 3454 O O   . SER B 2 371 ? 140.932 110.572 156.638 1.00 69.58  ? 372 SER A O   1 
ATOM 3455 C CB  . SER B 2 371 ? 141.320 109.909 153.744 1.00 58.44  ? 372 SER A CB  1 
ATOM 3456 O OG  . SER B 2 371 ? 141.896 109.653 152.477 1.00 66.99  ? 372 SER A OG  1 
ATOM 3457 N N   . LEU B 2 372 ? 142.043 112.434 156.012 1.00 55.19  ? 373 LEU A N   1 
ATOM 3458 C CA  . LEU B 2 372 ? 141.460 113.325 157.005 1.00 53.50  ? 373 LEU A CA  1 
ATOM 3459 C C   . LEU B 2 372 ? 140.929 114.574 156.325 1.00 63.60  ? 373 LEU A C   1 
ATOM 3460 O O   . LEU B 2 372 ? 141.046 115.690 156.836 1.00 70.77  ? 373 LEU A O   1 
ATOM 3461 C CB  . LEU B 2 372 ? 142.478 113.674 158.087 1.00 58.61  ? 373 LEU A CB  1 
ATOM 3462 C CG  . LEU B 2 372 ? 143.122 112.473 158.778 1.00 53.34  ? 373 LEU A CG  1 
ATOM 3463 C CD1 . LEU B 2 372 ? 144.337 112.896 159.580 1.00 65.22  ? 373 LEU A CD1 1 
ATOM 3464 C CD2 . LEU B 2 372 ? 142.112 111.778 159.668 1.00 55.65  ? 373 LEU A CD2 1 
ATOM 3465 N N   . GLN B 2 373 ? 140.340 114.388 155.149 1.00 72.16  ? 374 GLN A N   1 
ATOM 3466 C CA  . GLN B 2 373 ? 139.906 115.503 154.323 1.00 73.65  ? 374 GLN A CA  1 
ATOM 3467 C C   . GLN B 2 373 ? 138.614 116.108 154.858 1.00 79.20  ? 374 GLN A C   1 
ATOM 3468 O O   . GLN B 2 373 ? 137.736 115.399 155.352 1.00 92.22  ? 374 GLN A O   1 
ATOM 3469 C CB  . GLN B 2 373 ? 139.720 115.025 152.884 1.00 71.52  ? 374 GLN A CB  1 
ATOM 3470 C CG  . GLN B 2 373 ? 139.015 115.995 151.964 1.00 81.03  ? 374 GLN A CG  1 
ATOM 3471 C CD  . GLN B 2 373 ? 138.737 115.388 150.607 1.00 90.52  ? 374 GLN A CD  1 
ATOM 3472 O OE1 . GLN B 2 373 ? 139.212 114.296 150.296 1.00 89.68  ? 374 GLN A OE1 1 
ATOM 3473 N NE2 . GLN B 2 373 ? 137.965 116.092 149.788 1.00 88.74  ? 374 GLN A NE2 1 
ATOM 3474 N N   . ARG B 2 374 ? 138.510 117.433 154.765 1.00 76.91  ? 375 ARG A N   1 
ATOM 3475 C CA  . ARG B 2 374 ? 137.296 118.172 155.113 1.00 69.86  ? 375 ARG A CA  1 
ATOM 3476 C C   . ARG B 2 374 ? 136.881 117.912 156.562 1.00 73.61  ? 375 ARG A C   1 
ATOM 3477 O O   . ARG B 2 374 ? 135.756 117.507 156.857 1.00 81.21  ? 375 ARG A O   1 
ATOM 3478 C CB  . ARG B 2 374 ? 136.162 117.842 154.140 1.00 72.24  ? 375 ARG A CB  1 
ATOM 3479 C CG  . ARG B 2 374 ? 136.351 118.453 152.765 1.00 84.93  ? 375 ARG A CG  1 
ATOM 3480 C CD  . ARG B 2 374 ? 135.133 118.242 151.891 1.00 87.51  ? 375 ARG A CD  1 
ATOM 3481 N NE  . ARG B 2 374 ? 135.075 119.191 150.787 1.00 94.55  ? 375 ARG A NE  1 
ATOM 3482 C CZ  . ARG B 2 374 ? 134.612 120.430 150.887 1.00 96.60  ? 375 ARG A CZ  1 
ATOM 3483 N NH1 . ARG B 2 374 ? 134.158 120.908 152.034 1.00 94.68  ? 375 ARG A NH1 1 
ATOM 3484 N NH2 . ARG B 2 374 ? 134.606 121.209 149.809 1.00 90.48  ? 375 ARG A NH2 1 
ATOM 3485 N N   . ASN B 2 375 ? 137.840 118.129 157.464 1.00 80.90  ? 376 ASN A N   1 
ATOM 3486 C CA  . ASN B 2 375 ? 137.599 118.000 158.920 1.00 73.32  ? 376 ASN A CA  1 
ATOM 3487 C C   . ASN B 2 375 ? 137.946 119.361 159.523 1.00 81.72  ? 376 ASN A C   1 
ATOM 3488 O O   . ASN B 2 375 ? 138.145 120.298 158.726 1.00 87.65  ? 376 ASN A O   1 
ATOM 3489 C CB  . ASN B 2 375 ? 138.420 116.861 159.513 1.00 74.87  ? 376 ASN A CB  1 
ATOM 3490 C CG  . ASN B 2 375 ? 137.951 115.487 159.100 1.00 75.49  ? 376 ASN A CG  1 
ATOM 3491 O OD1 . ASN B 2 375 ? 137.212 115.335 158.125 1.00 81.75  ? 376 ASN A OD1 1 
ATOM 3492 N ND2 . ASN B 2 375 ? 138.383 114.469 159.826 1.00 73.50  ? 376 ASN A ND2 1 
ATOM 3493 N N   . GLN B 2 376 ? 138.017 119.485 160.845 1.00 89.60  ? 377 GLN A N   1 
ATOM 3494 C CA  . GLN B 2 376 ? 138.361 120.698 161.574 1.00 87.94  ? 377 GLN A CA  1 
ATOM 3495 C C   . GLN B 2 376 ? 139.689 120.564 162.311 1.00 89.40  ? 377 GLN A C   1 
ATOM 3496 O O   . GLN B 2 376 ? 139.873 121.149 163.380 1.00 96.89  ? 377 GLN A O   1 
ATOM 3497 C CB  . GLN B 2 376 ? 137.248 121.068 162.551 1.00 94.44  ? 377 GLN A CB  1 
ATOM 3498 C CG  . GLN B 2 376 ? 135.889 121.232 161.900 1.00 91.63  ? 377 GLN A CG  1 
ATOM 3499 C CD  . GLN B 2 376 ? 134.769 121.319 162.914 1.00 92.90  ? 377 GLN A CD  1 
ATOM 3500 O OE1 . GLN B 2 376 ? 134.955 121.006 164.089 1.00 92.25  ? 377 GLN A OE1 1 
ATOM 3501 N NE2 . GLN B 2 376 ? 133.596 121.746 162.464 1.00 96.82  ? 377 GLN A NE2 1 
ATOM 3502 N N   . ILE B 2 377 ? 140.623 119.794 161.753 1.00 83.17  ? 378 ILE A N   1 
ATOM 3503 C CA  . ILE B 2 377 ? 141.948 119.682 162.347 1.00 81.39  ? 378 ILE A CA  1 
ATOM 3504 C C   . ILE B 2 377 ? 142.679 121.005 162.177 1.00 81.85  ? 378 ILE A C   1 
ATOM 3505 O O   . ILE B 2 377 ? 142.707 121.581 161.082 1.00 88.47  ? 378 ILE A O   1 
ATOM 3506 C CB  . ILE B 2 377 ? 142.732 118.526 161.711 1.00 81.73  ? 378 ILE A CB  1 
ATOM 3507 C CG1 . ILE B 2 377 ? 141.972 117.211 161.874 1.00 80.09  ? 378 ILE A CG1 1 
ATOM 3508 C CG2 . ILE B 2 377 ? 144.107 118.410 162.340 1.00 87.62  ? 378 ILE A CG2 1 
ATOM 3509 C CD1 . ILE B 2 377 ? 141.875 116.407 160.605 1.00 76.51  ? 378 ILE A CD1 1 
ATOM 3510 N N   . TYR B 2 378 ? 143.267 121.501 163.263 1.00 83.91  ? 379 TYR A N   1 
ATOM 3511 C CA  . TYR B 2 378 ? 143.925 122.797 163.250 1.00 85.92  ? 379 TYR A CA  1 
ATOM 3512 C C   . TYR B 2 378 ? 145.413 122.733 163.557 1.00 92.11  ? 379 TYR A C   1 
ATOM 3513 O O   . TYR B 2 378 ? 146.068 123.780 163.566 1.00 101.52 ? 379 TYR A O   1 
ATOM 3514 C CB  . TYR B 2 378 ? 143.243 123.748 164.243 1.00 89.33  ? 379 TYR A CB  1 
ATOM 3515 C CG  . TYR B 2 378 ? 143.436 123.364 165.690 1.00 93.90  ? 379 TYR A CG  1 
ATOM 3516 C CD1 . TYR B 2 378 ? 142.647 122.388 166.280 1.00 94.87  ? 379 TYR A CD1 1 
ATOM 3517 C CD2 . TYR B 2 378 ? 144.405 123.981 166.469 1.00 98.09  ? 379 TYR A CD2 1 
ATOM 3518 C CE1 . TYR B 2 378 ? 142.819 122.034 167.602 1.00 95.33  ? 379 TYR A CE1 1 
ATOM 3519 C CE2 . TYR B 2 378 ? 144.584 123.633 167.792 1.00 99.67  ? 379 TYR A CE2 1 
ATOM 3520 C CZ  . TYR B 2 378 ? 143.788 122.659 168.353 1.00 97.57  ? 379 TYR A CZ  1 
ATOM 3521 O OH  . TYR B 2 378 ? 143.962 122.309 169.671 1.00 98.73  ? 379 TYR A OH  1 
ATOM 3522 N N   . GLN B 2 379 ? 145.968 121.550 163.808 1.00 86.92  ? 380 GLN A N   1 
ATOM 3523 C CA  . GLN B 2 379 ? 147.387 121.445 164.113 1.00 82.87  ? 380 GLN A CA  1 
ATOM 3524 C C   . GLN B 2 379 ? 147.861 120.025 163.846 1.00 89.87  ? 380 GLN A C   1 
ATOM 3525 O O   . GLN B 2 379 ? 147.129 119.064 164.091 1.00 95.58  ? 380 GLN A O   1 
ATOM 3526 C CB  . GLN B 2 379 ? 147.674 121.828 165.567 1.00 82.53  ? 380 GLN A CB  1 
ATOM 3527 C CG  . GLN B 2 379 ? 149.124 122.181 165.832 1.00 93.40  ? 380 GLN A CG  1 
ATOM 3528 C CD  . GLN B 2 379 ? 149.448 122.228 167.309 1.00 101.44 ? 380 GLN A CD  1 
ATOM 3529 O OE1 . GLN B 2 379 ? 148.606 121.917 168.151 1.00 98.20  ? 380 GLN A OE1 1 
ATOM 3530 N NE2 . GLN B 2 379 ? 150.676 122.614 167.633 1.00 101.11 ? 380 GLN A NE2 1 
ATOM 3531 N N   . ILE B 2 380 ? 149.086 119.908 163.342 1.00 92.57  ? 381 ILE A N   1 
ATOM 3532 C CA  . ILE B 2 380 ? 149.758 118.627 163.160 1.00 82.92  ? 381 ILE A CA  1 
ATOM 3533 C C   . ILE B 2 380 ? 151.009 118.655 164.024 1.00 84.49  ? 381 ILE A C   1 
ATOM 3534 O O   . ILE B 2 380 ? 151.933 119.435 163.763 1.00 91.81  ? 381 ILE A O   1 
ATOM 3535 C CB  . ILE B 2 380 ? 150.112 118.359 161.691 1.00 77.87  ? 381 ILE A CB  1 
ATOM 3536 C CG1 . ILE B 2 380 ? 148.910 118.632 160.789 1.00 84.33  ? 381 ILE A CG1 1 
ATOM 3537 C CG2 . ILE B 2 380 ? 150.594 116.932 161.515 1.00 74.64  ? 381 ILE A CG2 1 
ATOM 3538 C CD1 . ILE B 2 380 ? 147.769 117.675 160.999 1.00 82.75  ? 381 ILE A CD1 1 
ATOM 3539 N N   . LYS B 2 381 ? 151.044 117.813 165.049 1.00 96.47  ? 382 LYS A N   1 
ATOM 3540 C CA  . LYS B 2 381 ? 152.191 117.730 165.939 1.00 105.41 ? 382 LYS A CA  1 
ATOM 3541 C C   . LYS B 2 381 ? 153.092 116.573 165.527 1.00 105.16 ? 382 LYS A C   1 
ATOM 3542 O O   . LYS B 2 381 ? 152.671 115.641 164.838 1.00 111.74 ? 382 LYS A O   1 
ATOM 3543 C CB  . LYS B 2 381 ? 151.742 117.571 167.393 1.00 108.56 ? 382 LYS A CB  1 
ATOM 3544 C CG  . LYS B 2 381 ? 150.377 116.930 167.556 1.00 108.59 ? 382 LYS A CG  1 
ATOM 3545 C CD  . LYS B 2 381 ? 149.826 117.160 168.953 1.00 105.85 ? 382 LYS A CD  1 
ATOM 3546 C CE  . LYS B 2 381 ? 149.580 118.637 169.206 1.00 105.64 ? 382 LYS A CE  1 
ATOM 3547 N NZ  . LYS B 2 381 ? 148.685 118.858 170.374 1.00 108.84 ? 382 LYS A NZ  1 
ATOM 3548 N N   . GLU B 2 382 ? 154.352 116.648 165.962 1.00 106.30 ? 383 GLU A N   1 
ATOM 3549 C CA  . GLU B 2 382 ? 155.362 115.708 165.487 1.00 110.09 ? 383 GLU A CA  1 
ATOM 3550 C C   . GLU B 2 382 ? 155.058 114.268 165.880 1.00 112.84 ? 383 GLU A C   1 
ATOM 3551 O O   . GLU B 2 382 ? 155.561 113.345 165.232 1.00 116.55 ? 383 GLU A O   1 
ATOM 3552 C CB  . GLU B 2 382 ? 156.741 116.112 166.011 1.00 108.48 ? 383 GLU A CB  1 
ATOM 3553 C CG  . GLU B 2 382 ? 157.021 115.682 167.441 1.00 114.89 ? 383 GLU A CG  1 
ATOM 3554 C CD  . GLU B 2 382 ? 156.337 116.568 168.464 1.00 123.32 ? 383 GLU A CD  1 
ATOM 3555 O OE1 . GLU B 2 382 ? 155.667 117.542 168.061 1.00 122.15 ? 383 GLU A OE1 1 
ATOM 3556 O OE2 . GLU B 2 382 ? 156.468 116.287 169.674 1.00 125.27 ? 383 GLU A OE2 1 
ATOM 3557 N N   . GLY B 2 383 ? 154.253 114.052 166.916 1.00 100.60 ? 384 GLY A N   1 
ATOM 3558 C CA  . GLY B 2 383 ? 153.929 112.704 167.333 1.00 102.10 ? 384 GLY A CA  1 
ATOM 3559 C C   . GLY B 2 383 ? 152.777 112.051 166.608 1.00 104.07 ? 384 GLY A C   1 
ATOM 3560 O O   . GLY B 2 383 ? 152.561 110.847 166.771 1.00 109.76 ? 384 GLY A O   1 
ATOM 3561 N N   . THR B 2 384 ? 152.026 112.813 165.810 1.00 96.06  ? 385 THR A N   1 
ATOM 3562 C CA  . THR B 2 384 ? 150.832 112.264 165.174 1.00 95.74  ? 385 THR A CA  1 
ATOM 3563 C C   . THR B 2 384 ? 151.178 111.172 164.170 1.00 98.26  ? 385 THR A C   1 
ATOM 3564 O O   . THR B 2 384 ? 150.504 110.138 164.117 1.00 104.76 ? 385 THR A O   1 
ATOM 3565 C CB  . THR B 2 384 ? 150.039 113.378 164.494 1.00 98.26  ? 385 THR A CB  1 
ATOM 3566 O OG1 . THR B 2 384 ? 150.944 114.313 163.896 1.00 111.07 ? 385 THR A OG1 1 
ATOM 3567 C CG2 . THR B 2 384 ? 149.164 114.099 165.504 1.00 94.96  ? 385 THR A CG2 1 
ATOM 3568 N N   . PHE B 2 385 ? 152.221 111.378 163.368 1.00 84.06  ? 386 PHE A N   1 
ATOM 3569 C CA  . PHE B 2 385 ? 152.582 110.442 162.312 1.00 86.06  ? 386 PHE A CA  1 
ATOM 3570 C C   . PHE B 2 385 ? 153.907 109.742 162.581 1.00 94.37  ? 386 PHE A C   1 
ATOM 3571 O O   . PHE B 2 385 ? 154.544 109.246 161.647 1.00 100.09 ? 386 PHE A O   1 
ATOM 3572 C CB  . PHE B 2 385 ? 152.624 111.162 160.966 1.00 81.33  ? 386 PHE A CB  1 
ATOM 3573 C CG  . PHE B 2 385 ? 151.302 111.721 160.544 1.00 79.89  ? 386 PHE A CG  1 
ATOM 3574 C CD1 . PHE B 2 385 ? 150.182 110.913 160.493 1.00 79.48  ? 386 PHE A CD1 1 
ATOM 3575 C CD2 . PHE B 2 385 ? 151.174 113.054 160.206 1.00 85.78  ? 386 PHE A CD2 1 
ATOM 3576 C CE1 . PHE B 2 385 ? 148.961 111.423 160.106 1.00 84.13  ? 386 PHE A CE1 1 
ATOM 3577 C CE2 . PHE B 2 385 ? 149.955 113.570 159.820 1.00 84.09  ? 386 PHE A CE2 1 
ATOM 3578 C CZ  . PHE B 2 385 ? 148.848 112.753 159.769 1.00 83.23  ? 386 PHE A CZ  1 
ATOM 3579 N N   . GLN B 2 386 ? 154.334 109.689 163.838 1.00 110.72 ? 387 GLN A N   1 
ATOM 3580 C CA  . GLN B 2 386 ? 155.585 109.027 164.171 1.00 113.01 ? 387 GLN A CA  1 
ATOM 3581 C C   . GLN B 2 386 ? 155.435 107.515 164.068 1.00 112.25 ? 387 GLN A C   1 
ATOM 3582 O O   . GLN B 2 386 ? 154.461 106.936 164.554 1.00 104.43 ? 387 GLN A O   1 
ATOM 3583 C CB  . GLN B 2 386 ? 156.031 109.415 165.579 1.00 112.50 ? 387 GLN A CB  1 
ATOM 3584 C CG  . GLN B 2 386 ? 157.333 108.772 166.013 1.00 112.42 ? 387 GLN A CG  1 
ATOM 3585 C CD  . GLN B 2 386 ? 157.865 109.356 167.304 1.00 118.05 ? 387 GLN A CD  1 
ATOM 3586 O OE1 . GLN B 2 386 ? 157.337 110.342 167.816 1.00 118.13 ? 387 GLN A OE1 1 
ATOM 3587 N NE2 . GLN B 2 386 ? 158.919 108.750 167.838 1.00 116.85 ? 387 GLN A NE2 1 
ATOM 3588 N N   . GLY B 2 387 ? 156.410 106.875 163.425 1.00 114.64 ? 388 GLY A N   1 
ATOM 3589 C CA  . GLY B 2 387 ? 156.441 105.433 163.325 1.00 114.76 ? 388 GLY A CA  1 
ATOM 3590 C C   . GLY B 2 387 ? 155.620 104.712 162.280 1.00 111.71 ? 388 GLY A C   1 
ATOM 3591 O O   . GLY B 2 387 ? 155.658 103.477 162.234 1.00 111.27 ? 388 GLY A O   1 
ATOM 3592 N N   . LEU B 2 388 ? 154.878 105.432 161.438 1.00 96.43  ? 389 LEU A N   1 
ATOM 3593 C CA  . LEU B 2 388 ? 154.085 104.791 160.384 1.00 91.16  ? 389 LEU A CA  1 
ATOM 3594 C C   . LEU B 2 388 ? 155.084 104.498 159.244 1.00 97.10  ? 389 LEU A C   1 
ATOM 3595 O O   . LEU B 2 388 ? 155.367 105.310 158.360 1.00 104.62 ? 389 LEU A O   1 
ATOM 3596 C CB  . LEU B 2 388 ? 152.958 105.705 159.927 1.00 97.17  ? 389 LEU A CB  1 
ATOM 3597 C CG  . LEU B 2 388 ? 151.869 106.017 160.955 1.00 98.47  ? 389 LEU A CG  1 
ATOM 3598 C CD1 . LEU B 2 388 ? 150.899 107.049 160.410 1.00 98.55  ? 389 LEU A CD1 1 
ATOM 3599 C CD2 . LEU B 2 388 ? 151.134 104.760 161.364 1.00 100.86 ? 389 LEU A CD2 1 
ATOM 3600 N N   . ILE B 2 389 ? 155.665 103.301 159.332 1.00 92.24  ? 390 ILE A N   1 
ATOM 3601 C CA  . ILE B 2 389 ? 156.809 102.966 158.491 1.00 95.58  ? 390 ILE A CA  1 
ATOM 3602 C C   . ILE B 2 389 ? 156.316 102.663 157.081 1.00 95.95  ? 390 ILE A C   1 
ATOM 3603 O O   . ILE B 2 389 ? 157.104 102.677 156.128 1.00 100.56 ? 390 ILE A O   1 
ATOM 3604 C CB  . ILE B 2 389 ? 157.468 101.734 159.139 1.00 95.51  ? 390 ILE A CB  1 
ATOM 3605 C CG1 . ILE B 2 389 ? 158.854 101.494 158.539 1.00 98.48  ? 390 ILE A CG1 1 
ATOM 3606 C CG2 . ILE B 2 389 ? 156.592 100.501 158.979 1.00 91.21  ? 390 ILE A CG2 1 
ATOM 3607 C CD1 . ILE B 2 389 ? 159.768 102.695 158.625 1.00 95.81  ? 390 ILE A CD1 1 
ATOM 3608 N N   . SER B 2 390 ? 155.024 102.390 156.911 1.00 77.45  ? 391 SER A N   1 
ATOM 3609 C CA  . SER B 2 390 ? 154.492 101.983 155.617 1.00 78.55  ? 391 SER A CA  1 
ATOM 3610 C C   . SER B 2 390 ? 153.491 102.952 155.005 1.00 83.69  ? 391 SER A C   1 
ATOM 3611 O O   . SER B 2 390 ? 152.873 102.623 153.988 1.00 84.12  ? 391 SER A O   1 
ATOM 3612 C CB  . SER B 2 390 ? 153.807 100.622 155.732 1.00 84.27  ? 391 SER A CB  1 
ATOM 3613 O OG  . SER B 2 390 ? 153.307 100.202 154.476 1.00 93.09  ? 391 SER A OG  1 
ATOM 3614 N N   . LEU B 2 391 ? 153.323 104.140 155.600 1.00 87.05  ? 392 LEU A N   1 
ATOM 3615 C CA  . LEU B 2 391 ? 152.346 105.139 155.094 1.00 84.09  ? 392 LEU A CA  1 
ATOM 3616 C C   . LEU B 2 391 ? 152.826 105.646 153.728 1.00 83.42  ? 392 LEU A C   1 
ATOM 3617 O O   . LEU B 2 391 ? 153.996 106.078 153.664 1.00 95.68  ? 392 LEU A O   1 
ATOM 3618 C CB  . LEU B 2 391 ? 152.149 106.295 156.075 1.00 78.73  ? 392 LEU A CB  1 
ATOM 3619 C CG  . LEU B 2 391 ? 151.095 107.336 155.681 1.00 74.43  ? 392 LEU A CG  1 
ATOM 3620 C CD1 . LEU B 2 391 ? 149.741 106.713 155.380 1.00 84.41  ? 392 LEU A CD1 1 
ATOM 3621 C CD2 . LEU B 2 391 ? 150.964 108.374 156.776 1.00 80.32  ? 392 LEU A CD2 1 
ATOM 3622 N N   . ARG B 2 392 ? 151.973 105.609 152.698 1.00 67.53  ? 393 ARG A N   1 
ATOM 3623 C CA  . ARG B 2 392 ? 152.304 106.062 151.353 1.00 62.09  ? 393 ARG A CA  1 
ATOM 3624 C C   . ARG B 2 392 ? 151.517 107.287 150.926 1.00 70.84  ? 393 ARG A C   1 
ATOM 3625 O O   . ARG B 2 392 ? 152.072 108.170 150.270 1.00 87.82  ? 393 ARG A O   1 
ATOM 3626 C CB  . ARG B 2 392 ? 152.007 104.917 150.379 1.00 71.16  ? 393 ARG A CB  1 
ATOM 3627 C CG  . ARG B 2 392 ? 152.989 103.765 150.435 1.00 80.57  ? 393 ARG A CG  1 
ATOM 3628 C CD  . ARG B 2 392 ? 152.826 102.847 149.232 1.00 83.16  ? 393 ARG A CD  1 
ATOM 3629 N NE  . ARG B 2 392 ? 151.505 102.232 149.177 1.00 90.23  ? 393 ARG A NE  1 
ATOM 3630 C CZ  . ARG B 2 392 ? 150.506 102.660 148.417 1.00 90.56  ? 393 ARG A CZ  1 
ATOM 3631 N NH1 . ARG B 2 392 ? 150.642 103.711 147.625 1.00 85.23  ? 393 ARG A NH1 1 
ATOM 3632 N NH2 . ARG B 2 392 ? 149.342 102.020 148.453 1.00 83.11  ? 393 ARG A NH2 1 
ATOM 3633 N N   . ILE B 2 393 ? 150.236 107.367 151.275 1.00 66.53  ? 394 ILE A N   1 
ATOM 3634 C CA  . ILE B 2 393 ? 149.371 108.467 150.871 1.00 65.81  ? 394 ILE A CA  1 
ATOM 3635 C C   . ILE B 2 393 ? 148.808 109.122 152.123 1.00 71.96  ? 394 ILE A C   1 
ATOM 3636 O O   . ILE B 2 393 ? 148.304 108.434 153.016 1.00 85.45  ? 394 ILE A O   1 
ATOM 3637 C CB  . ILE B 2 393 ? 148.234 107.989 149.952 1.00 65.81  ? 394 ILE A CB  1 
ATOM 3638 C CG1 . ILE B 2 393 ? 148.805 107.254 148.739 1.00 70.86  ? 394 ILE A CG1 1 
ATOM 3639 C CG2 . ILE B 2 393 ? 147.375 109.163 149.518 1.00 72.65  ? 394 ILE A CG2 1 
ATOM 3640 C CD1 . ILE B 2 393 ? 147.821 107.088 147.605 1.00 76.80  ? 394 ILE A CD1 1 
ATOM 3641 N N   . LEU B 2 394 ? 148.893 110.448 152.183 1.00 61.24  ? 395 LEU A N   1 
ATOM 3642 C CA  . LEU B 2 394 ? 148.375 111.220 153.303 1.00 57.96  ? 395 LEU A CA  1 
ATOM 3643 C C   . LEU B 2 394 ? 147.549 112.373 152.760 1.00 57.40  ? 395 LEU A C   1 
ATOM 3644 O O   . LEU B 2 394 ? 147.993 113.082 151.853 1.00 70.73  ? 395 LEU A O   1 
ATOM 3645 C CB  . LEU B 2 394 ? 149.510 111.744 154.184 1.00 54.77  ? 395 LEU A CB  1 
ATOM 3646 C CG  . LEU B 2 394 ? 149.099 112.450 155.472 1.00 56.17  ? 395 LEU A CG  1 
ATOM 3647 C CD1 . LEU B 2 394 ? 148.026 111.657 156.191 1.00 63.26  ? 395 LEU A CD1 1 
ATOM 3648 C CD2 . LEU B 2 394 ? 150.308 112.643 156.364 1.00 65.03  ? 395 LEU A CD2 1 
ATOM 3649 N N   . ASP B 2 395 ? 146.353 112.558 153.311 1.00 70.30  ? 396 ASP A N   1 
ATOM 3650 C CA  . ASP B 2 395 ? 145.441 113.597 152.852 1.00 66.91  ? 396 ASP A CA  1 
ATOM 3651 C C   . ASP B 2 395 ? 145.012 114.455 154.031 1.00 71.67  ? 396 ASP A C   1 
ATOM 3652 O O   . ASP B 2 395 ? 144.505 113.937 155.029 1.00 82.20  ? 396 ASP A O   1 
ATOM 3653 C CB  . ASP B 2 395 ? 144.216 112.991 152.163 1.00 75.08  ? 396 ASP A CB  1 
ATOM 3654 C CG  . ASP B 2 395 ? 143.526 113.969 151.237 1.00 84.37  ? 396 ASP A CG  1 
ATOM 3655 O OD1 . ASP B 2 395 ? 143.608 115.189 151.486 1.00 86.29  ? 396 ASP A OD1 1 
ATOM 3656 O OD2 . ASP B 2 395 ? 142.902 113.517 150.255 1.00 92.32  ? 396 ASP A OD2 1 
ATOM 3657 N N   . LEU B 2 396 ? 145.219 115.766 153.908 1.00 62.67  ? 397 LEU A N   1 
ATOM 3658 C CA  . LEU B 2 396 ? 144.802 116.727 154.920 1.00 58.72  ? 397 LEU A CA  1 
ATOM 3659 C C   . LEU B 2 396 ? 144.119 117.924 154.275 1.00 65.58  ? 397 LEU A C   1 
ATOM 3660 O O   . LEU B 2 396 ? 144.154 119.033 154.819 1.00 74.15  ? 397 LEU A O   1 
ATOM 3661 C CB  . LEU B 2 396 ? 145.989 117.194 155.760 1.00 60.09  ? 397 LEU A CB  1 
ATOM 3662 C CG  . LEU B 2 396 ? 146.802 116.109 156.462 1.00 64.99  ? 397 LEU A CG  1 
ATOM 3663 C CD1 . LEU B 2 396 ? 148.127 116.666 156.947 1.00 67.47  ? 397 LEU A CD1 1 
ATOM 3664 C CD2 . LEU B 2 396 ? 146.011 115.530 157.616 1.00 62.70  ? 397 LEU A CD2 1 
ATOM 3665 N N   . SER B 2 397 ? 143.502 117.717 153.118 1.00 65.58  ? 398 SER A N   1 
ATOM 3666 C CA  . SER B 2 397 ? 142.923 118.811 152.357 1.00 69.70  ? 398 SER A CA  1 
ATOM 3667 C C   . SER B 2 397 ? 141.713 119.404 153.070 1.00 73.50  ? 398 SER A C   1 
ATOM 3668 O O   . SER B 2 397 ? 140.972 118.711 153.771 1.00 85.87  ? 398 SER A O   1 
ATOM 3669 C CB  . SER B 2 397 ? 142.522 118.327 150.965 1.00 77.77  ? 398 SER A CB  1 
ATOM 3670 O OG  . SER B 2 397 ? 141.714 119.282 150.304 1.00 86.34  ? 398 SER A OG  1 
ATOM 3671 N N   . ARG B 2 398 ? 141.528 120.710 152.882 1.00 75.53  ? 399 ARG A N   1 
ATOM 3672 C CA  . ARG B 2 398 ? 140.344 121.439 153.337 1.00 69.97  ? 399 ARG A CA  1 
ATOM 3673 C C   . ARG B 2 398 ? 140.115 121.278 154.841 1.00 70.73  ? 399 ARG A C   1 
ATOM 3674 O O   . ARG B 2 398 ? 139.063 120.832 155.296 1.00 78.42  ? 399 ARG A O   1 
ATOM 3675 C CB  . ARG B 2 398 ? 139.108 121.004 152.547 1.00 70.26  ? 399 ARG A CB  1 
ATOM 3676 C CG  . ARG B 2 398 ? 139.258 121.197 151.056 1.00 76.44  ? 399 ARG A CG  1 
ATOM 3677 C CD  . ARG B 2 398 ? 138.005 120.797 150.310 1.00 82.90  ? 399 ARG A CD  1 
ATOM 3678 N NE  . ARG B 2 398 ? 138.120 121.073 148.883 1.00 87.59  ? 399 ARG A NE  1 
ATOM 3679 C CZ  . ARG B 2 398 ? 137.997 122.276 148.340 1.00 88.53  ? 399 ARG A CZ  1 
ATOM 3680 N NH1 . ARG B 2 398 ? 137.749 123.346 149.077 1.00 82.89  ? 399 ARG A NH1 1 
ATOM 3681 N NH2 . ARG B 2 398 ? 138.124 122.409 147.023 1.00 87.39  ? 399 ARG A NH2 1 
ATOM 3682 N N   . ASN B 2 399 ? 141.105 121.595 155.658 1.00 76.10  ? 400 ASN A N   1 
ATOM 3683 C CA  . ASN B 2 399 ? 140.923 121.622 157.129 1.00 75.28  ? 400 ASN A CA  1 
ATOM 3684 C C   . ASN B 2 399 ? 141.360 123.014 157.577 1.00 80.62  ? 400 ASN A C   1 
ATOM 3685 O O   . ASN B 2 399 ? 141.489 123.855 156.703 1.00 88.58  ? 400 ASN A O   1 
ATOM 3686 C CB  . ASN B 2 399 ? 141.653 120.523 157.887 1.00 78.33  ? 400 ASN A CB  1 
ATOM 3687 C CG  . ASN B 2 399 ? 141.517 119.129 157.341 1.00 78.36  ? 400 ASN A CG  1 
ATOM 3688 O OD1 . ASN B 2 399 ? 140.822 118.894 156.358 1.00 88.39  ? 400 ASN A OD1 1 
ATOM 3689 N ND2 . ASN B 2 399 ? 142.200 118.189 157.966 1.00 77.01  ? 400 ASN A ND2 1 
ATOM 3690 N N   . LEU B 2 400 ? 141.532 123.262 158.868 1.00 82.24  ? 401 LEU A N   1 
ATOM 3691 C CA  . LEU B 2 400 ? 141.929 124.531 159.460 1.00 80.41  ? 401 LEU A CA  1 
ATOM 3692 C C   . LEU B 2 400 ? 143.331 124.474 160.058 1.00 83.76  ? 401 LEU A C   1 
ATOM 3693 O O   . LEU B 2 400 ? 143.616 125.146 161.050 1.00 95.18  ? 401 LEU A O   1 
ATOM 3694 C CB  . LEU B 2 400 ? 140.919 124.958 160.523 1.00 88.40  ? 401 LEU A CB  1 
ATOM 3695 C CG  . LEU B 2 400 ? 139.448 124.634 160.264 1.00 86.34  ? 401 LEU A CG  1 
ATOM 3696 C CD1 . LEU B 2 400 ? 138.604 125.044 161.456 1.00 82.46  ? 401 LEU A CD1 1 
ATOM 3697 C CD2 . LEU B 2 400 ? 138.961 125.320 159.001 1.00 84.62  ? 401 LEU A CD2 1 
ATOM 3698 N N   . ILE B 2 401 ? 144.215 123.674 159.463 1.00 81.76  ? 402 ILE A N   1 
ATOM 3699 C CA  . ILE B 2 401 ? 145.577 123.558 159.967 1.00 83.88  ? 402 ILE A CA  1 
ATOM 3700 C C   . ILE B 2 401 ? 146.317 124.864 159.724 1.00 85.25  ? 402 ILE A C   1 
ATOM 3701 O O   . ILE B 2 401 ? 146.362 125.372 158.596 1.00 85.82  ? 402 ILE A O   1 
ATOM 3702 C CB  . ILE B 2 401 ? 146.302 122.381 159.301 1.00 83.60  ? 402 ILE A CB  1 
ATOM 3703 C CG1 . ILE B 2 401 ? 145.503 121.091 159.479 1.00 86.86  ? 402 ILE A CG1 1 
ATOM 3704 C CG2 . ILE B 2 401 ? 147.694 122.221 159.881 1.00 86.53  ? 402 ILE A CG2 1 
ATOM 3705 C CD1 . ILE B 2 401 ? 146.013 119.947 158.640 1.00 84.43  ? 402 ILE A CD1 1 
ATOM 3706 N N   . HIS B 2 402 ? 146.900 125.418 160.784 1.00 91.38  ? 403 HIS A N   1 
ATOM 3707 C CA  . HIS B 2 402 ? 147.691 126.631 160.677 1.00 92.28  ? 403 HIS A CA  1 
ATOM 3708 C C   . HIS B 2 402 ? 149.109 126.466 161.198 1.00 95.66  ? 403 HIS A C   1 
ATOM 3709 O O   . HIS B 2 402 ? 149.887 127.425 161.147 1.00 99.70  ? 403 HIS A O   1 
ATOM 3710 C CB  . HIS B 2 402 ? 147.003 127.790 161.413 1.00 93.58  ? 403 HIS A CB  1 
ATOM 3711 C CG  . HIS B 2 402 ? 146.702 127.505 162.851 1.00 98.43  ? 403 HIS A CG  1 
ATOM 3712 N ND1 . HIS B 2 402 ? 145.416 127.447 163.343 1.00 103.53 ? 403 HIS A ND1 1 
ATOM 3713 C CD2 . HIS B 2 402 ? 147.519 127.271 163.905 1.00 97.59  ? 403 HIS A CD2 1 
ATOM 3714 C CE1 . HIS B 2 402 ? 145.454 127.184 164.637 1.00 98.79  ? 403 HIS A CE1 1 
ATOM 3715 N NE2 . HIS B 2 402 ? 146.718 127.072 165.003 1.00 100.72 ? 403 HIS A NE2 1 
ATOM 3716 N N   . GLU B 2 403 ? 149.470 125.286 161.694 1.00 96.76  ? 404 GLU A N   1 
ATOM 3717 C CA  . GLU B 2 403 ? 150.819 125.049 162.192 1.00 100.08 ? 404 GLU A CA  1 
ATOM 3718 C C   . GLU B 2 403 ? 151.151 123.576 162.024 1.00 100.55 ? 404 GLU A C   1 
ATOM 3719 O O   . GLU B 2 403 ? 150.436 122.716 162.544 1.00 99.55  ? 404 GLU A O   1 
ATOM 3720 C CB  . GLU B 2 403 ? 150.947 125.464 163.658 1.00 101.84 ? 404 GLU A CB  1 
ATOM 3721 C CG  . GLU B 2 403 ? 152.197 124.936 164.343 1.00 103.37 ? 404 GLU A CG  1 
ATOM 3722 C CD  . GLU B 2 403 ? 153.389 125.861 164.188 1.00 109.00 ? 404 GLU A CD  1 
ATOM 3723 O OE1 . GLU B 2 403 ? 153.497 126.530 163.140 1.00 107.61 ? 404 GLU A OE1 1 
ATOM 3724 O OE2 . GLU B 2 403 ? 154.222 125.916 165.117 1.00 112.08 ? 404 GLU A OE2 1 
ATOM 3725 N N   . ILE B 2 404 ? 152.230 123.293 161.301 1.00 98.75  ? 405 ILE A N   1 
ATOM 3726 C CA  . ILE B 2 404 ? 152.755 121.944 161.147 1.00 90.80  ? 405 ILE A CA  1 
ATOM 3727 C C   . ILE B 2 404 ? 154.155 121.919 161.739 1.00 91.05  ? 405 ILE A C   1 
ATOM 3728 O O   . ILE B 2 404 ? 154.991 122.764 161.400 1.00 96.59  ? 405 ILE A O   1 
ATOM 3729 C CB  . ILE B 2 404 ? 152.780 121.501 159.673 1.00 82.58  ? 405 ILE A CB  1 
ATOM 3730 C CG1 . ILE B 2 404 ? 151.385 121.607 159.060 1.00 82.42  ? 405 ILE A CG1 1 
ATOM 3731 C CG2 . ILE B 2 404 ? 153.300 120.084 159.558 1.00 90.04  ? 405 ILE A CG2 1 
ATOM 3732 C CD1 . ILE B 2 404 ? 151.307 121.088 157.643 1.00 84.22  ? 405 ILE A CD1 1 
ATOM 3733 N N   . HIS B 2 405 ? 154.402 120.963 162.630 1.00 100.60 ? 406 HIS A N   1 
ATOM 3734 C CA  . HIS B 2 405 ? 155.716 120.843 163.245 1.00 106.69 ? 406 HIS A CA  1 
ATOM 3735 C C   . HIS B 2 405 ? 156.775 120.601 162.178 1.00 104.91 ? 406 HIS A C   1 
ATOM 3736 O O   . HIS B 2 405 ? 156.536 119.901 161.191 1.00 107.58 ? 406 HIS A O   1 
ATOM 3737 C CB  . HIS B 2 405 ? 155.718 119.707 164.265 1.00 108.99 ? 406 HIS A CB  1 
ATOM 3738 C CG  . HIS B 2 405 ? 156.864 119.760 165.226 1.00 108.13 ? 406 HIS A CG  1 
ATOM 3739 N ND1 . HIS B 2 405 ? 158.169 119.535 164.842 1.00 108.06 ? 406 HIS A ND1 1 
ATOM 3740 C CD2 . HIS B 2 405 ? 156.901 120.010 166.555 1.00 107.48 ? 406 HIS A CD2 1 
ATOM 3741 C CE1 . HIS B 2 405 ? 158.959 119.645 165.894 1.00 110.14 ? 406 HIS A CE1 1 
ATOM 3742 N NE2 . HIS B 2 405 ? 158.215 119.933 166.946 1.00 110.24 ? 406 HIS A NE2 1 
ATOM 3743 N N   . SER B 2 406 ? 157.952 121.198 162.379 1.00 97.83  ? 407 SER A N   1 
ATOM 3744 C CA  . SER B 2 406 ? 159.002 121.126 161.368 1.00 99.53  ? 407 SER A CA  1 
ATOM 3745 C C   . SER B 2 406 ? 159.451 119.693 161.115 1.00 105.43 ? 407 SER A C   1 
ATOM 3746 O O   . SER B 2 406 ? 159.936 119.381 160.021 1.00 110.86 ? 407 SER A O   1 
ATOM 3747 C CB  . SER B 2 406 ? 160.193 121.986 161.787 1.00 103.30 ? 407 SER A CB  1 
ATOM 3748 O OG  . SER B 2 406 ? 161.060 121.268 162.646 1.00 106.83 ? 407 SER A OG  1 
ATOM 3749 N N   . ARG B 2 407 ? 159.304 118.812 162.102 1.00 105.67 ? 408 ARG A N   1 
ATOM 3750 C CA  . ARG B 2 407 ? 159.696 117.415 161.971 1.00 105.13 ? 408 ARG A CA  1 
ATOM 3751 C C   . ARG B 2 407 ? 158.495 116.476 162.028 1.00 104.84 ? 408 ARG A C   1 
ATOM 3752 O O   . ARG B 2 407 ? 158.604 115.349 162.516 1.00 107.96 ? 408 ARG A O   1 
ATOM 3753 C CB  . ARG B 2 407 ? 160.712 117.045 163.049 1.00 104.73 ? 408 ARG A CB  1 
ATOM 3754 C CG  . ARG B 2 407 ? 162.112 117.565 162.779 1.00 101.97 ? 408 ARG A CG  1 
ATOM 3755 C CD  . ARG B 2 407 ? 162.995 117.420 164.004 1.00 105.03 ? 408 ARG A CD  1 
ATOM 3756 N NE  . ARG B 2 407 ? 162.756 116.162 164.700 1.00 112.01 ? 408 ARG A NE  1 
ATOM 3757 C CZ  . ARG B 2 407 ? 163.244 114.990 164.318 1.00 112.67 ? 408 ARG A CZ  1 
ATOM 3758 N NH1 . ARG B 2 407 ? 164.007 114.876 163.243 1.00 111.40 ? 408 ARG A NH1 1 
ATOM 3759 N NH2 . ARG B 2 407 ? 162.958 113.904 165.031 1.00 109.67 ? 408 ARG A NH2 1 
ATOM 3760 N N   . ALA B 2 408 ? 157.339 116.932 161.540 1.00 95.84  ? 409 ALA A N   1 
ATOM 3761 C CA  . ALA B 2 408 ? 156.148 116.090 161.552 1.00 93.70  ? 409 ALA A CA  1 
ATOM 3762 C C   . ALA B 2 408 ? 156.329 114.859 160.675 1.00 100.23 ? 409 ALA A C   1 
ATOM 3763 O O   . ALA B 2 408 ? 155.910 113.756 161.045 1.00 104.33 ? 409 ALA A O   1 
ATOM 3764 C CB  . ALA B 2 408 ? 154.931 116.895 161.099 1.00 90.62  ? 409 ALA A CB  1 
ATOM 3765 N N   . PHE B 2 409 ? 156.949 115.025 159.509 1.00 90.20  ? 410 PHE A N   1 
ATOM 3766 C CA  . PHE B 2 409 ? 157.182 113.931 158.577 1.00 86.06  ? 410 PHE A CA  1 
ATOM 3767 C C   . PHE B 2 409 ? 158.601 113.386 158.654 1.00 83.58  ? 410 PHE A C   1 
ATOM 3768 O O   . PHE B 2 409 ? 159.006 112.621 157.774 1.00 87.45  ? 410 PHE A O   1 
ATOM 3769 C CB  . PHE B 2 409 ? 156.879 114.383 157.149 1.00 82.98  ? 410 PHE A CB  1 
ATOM 3770 C CG  . PHE B 2 409 ? 155.628 115.198 157.023 1.00 80.83  ? 410 PHE A CG  1 
ATOM 3771 C CD1 . PHE B 2 409 ? 154.412 114.690 157.439 1.00 78.67  ? 410 PHE A CD1 1 
ATOM 3772 C CD2 . PHE B 2 409 ? 155.667 116.471 156.485 1.00 81.74  ? 410 PHE A CD2 1 
ATOM 3773 C CE1 . PHE B 2 409 ? 153.258 115.438 157.322 1.00 80.61  ? 410 PHE A CE1 1 
ATOM 3774 C CE2 . PHE B 2 409 ? 154.517 117.222 156.366 1.00 80.87  ? 410 PHE A CE2 1 
ATOM 3775 C CZ  . PHE B 2 409 ? 153.312 116.705 156.784 1.00 77.85  ? 410 PHE A CZ  1 
ATOM 3776 N N   . ALA B 2 410 ? 159.366 113.767 159.679 1.00 92.96  ? 411 ALA A N   1 
ATOM 3777 C CA  . ALA B 2 410 ? 160.774 113.387 159.741 1.00 99.55  ? 411 ALA A CA  1 
ATOM 3778 C C   . ALA B 2 410 ? 161.118 111.907 159.638 1.00 102.40 ? 411 ALA A C   1 
ATOM 3779 O O   . ALA B 2 410 ? 161.865 111.493 158.745 1.00 107.06 ? 411 ALA A O   1 
ATOM 3780 C CB  . ALA B 2 410 ? 161.445 114.071 160.931 1.00 102.21 ? 411 ALA A CB  1 
ATOM 3781 N N   . THR B 2 411 ? 160.536 111.082 160.484 1.00 115.29 ? 412 THR A N   1 
ATOM 3782 C CA  . THR B 2 411 ? 160.800 109.632 160.470 1.00 118.05 ? 412 THR A CA  1 
ATOM 3783 C C   . THR B 2 411 ? 159.715 108.740 159.792 1.00 115.03 ? 412 THR A C   1 
ATOM 3784 O O   . THR B 2 411 ? 159.746 107.511 159.715 1.00 117.81 ? 412 THR A O   1 
ATOM 3785 C CB  . THR B 2 411 ? 160.691 109.114 161.892 1.00 120.79 ? 412 THR A CB  1 
ATOM 3786 O OG1 . THR B 2 411 ? 161.162 107.772 161.865 1.00 121.84 ? 412 THR A OG1 1 
ATOM 3787 C CG2 . THR B 2 411 ? 159.263 109.124 162.394 1.00 113.52 ? 412 THR A CG2 1 
ATOM 3788 N N   . LEU B 2 412 ? 158.697 109.495 159.333 1.00 101.17 ? 413 LEU A N   1 
ATOM 3789 C CA  . LEU B 2 412 ? 157.620 108.880 158.539 1.00 101.19 ? 413 LEU A CA  1 
ATOM 3790 C C   . LEU B 2 412 ? 158.345 108.214 157.386 1.00 103.84 ? 413 LEU A C   1 
ATOM 3791 O O   . LEU B 2 412 ? 159.318 108.814 156.879 1.00 101.63 ? 413 LEU A O   1 
ATOM 3792 C CB  . LEU B 2 412 ? 156.649 109.956 158.061 1.00 100.10 ? 413 LEU A CB  1 
ATOM 3793 C CG  . LEU B 2 412 ? 155.345 109.477 157.418 1.00 103.64 ? 413 LEU A CG  1 
ATOM 3794 C CD1 . LEU B 2 412 ? 154.322 110.591 157.552 1.00 103.93 ? 413 LEU A CD1 1 
ATOM 3795 C CD2 . LEU B 2 412 ? 155.520 109.071 155.962 1.00 103.64 ? 413 LEU A CD2 1 
ATOM 3796 N N   . GLY B 2 413 ? 157.894 107.047 156.974 1.00 106.74 ? 414 GLY A N   1 
ATOM 3797 C CA  . GLY B 2 413 ? 158.551 106.248 155.967 1.00 104.45 ? 414 GLY A CA  1 
ATOM 3798 C C   . GLY B 2 413 ? 158.449 106.818 154.566 1.00 107.29 ? 414 GLY A C   1 
ATOM 3799 O O   . GLY B 2 413 ? 158.346 108.031 154.366 1.00 112.42 ? 414 GLY A O   1 
ATOM 3800 N N   . PRO B 2 414 ? 158.486 105.941 153.559 1.00 92.69  ? 415 PRO A N   1 
ATOM 3801 C CA  . PRO B 2 414 ? 158.461 106.394 152.161 1.00 88.06  ? 415 PRO A CA  1 
ATOM 3802 C C   . PRO B 2 414 ? 157.057 106.790 151.735 1.00 83.30  ? 415 PRO A C   1 
ATOM 3803 O O   . PRO B 2 414 ? 156.191 105.938 151.514 1.00 87.72  ? 415 PRO A O   1 
ATOM 3804 C CB  . PRO B 2 414 ? 158.968 105.165 151.394 1.00 92.00  ? 415 PRO A CB  1 
ATOM 3805 C CG  . PRO B 2 414 ? 158.560 104.006 152.239 1.00 93.25  ? 415 PRO A CG  1 
ATOM 3806 C CD  . PRO B 2 414 ? 158.539 104.474 153.672 1.00 91.48  ? 415 PRO A CD  1 
ATOM 3807 N N   . ILE B 2 415 ? 156.835 108.093 151.594 1.00 73.72  ? 416 ILE A N   1 
ATOM 3808 C CA  . ILE B 2 415 ? 155.527 108.650 151.270 1.00 74.55  ? 416 ILE A CA  1 
ATOM 3809 C C   . ILE B 2 415 ? 155.603 109.265 149.881 1.00 75.43  ? 416 ILE A C   1 
ATOM 3810 O O   . ILE B 2 415 ? 156.559 109.983 149.565 1.00 93.59  ? 416 ILE A O   1 
ATOM 3811 C CB  . ILE B 2 415 ? 155.087 109.690 152.314 1.00 68.24  ? 416 ILE A CB  1 
ATOM 3812 C CG1 . ILE B 2 415 ? 153.872 110.473 151.821 1.00 72.19  ? 416 ILE A CG1 1 
ATOM 3813 C CG2 . ILE B 2 415 ? 156.228 110.640 152.631 1.00 71.95  ? 416 ILE A CG2 1 
ATOM 3814 C CD1 . ILE B 2 415 ? 153.338 111.454 152.834 1.00 76.36  ? 416 ILE A CD1 1 
ATOM 3815 N N   . THR B 2 416 ? 154.606 108.976 149.049 1.00 71.88  ? 417 THR A N   1 
ATOM 3816 C CA  . THR B 2 416 ? 154.563 109.507 147.693 1.00 73.22  ? 417 THR A CA  1 
ATOM 3817 C C   . THR B 2 416 ? 153.635 110.707 147.559 1.00 75.79  ? 417 THR A C   1 
ATOM 3818 O O   . THR B 2 416 ? 154.017 111.718 146.964 1.00 91.44  ? 417 THR A O   1 
ATOM 3819 C CB  . THR B 2 416 ? 154.135 108.414 146.709 1.00 83.88  ? 417 THR A CB  1 
ATOM 3820 O OG1 . THR B 2 416 ? 152.705 108.351 146.656 1.00 96.20  ? 417 THR A OG1 1 
ATOM 3821 C CG2 . THR B 2 416 ? 154.685 107.065 147.139 1.00 84.99  ? 417 THR A CG2 1 
ATOM 3822 N N   . ASN B 2 417 ? 152.422 110.618 148.094 1.00 64.83  ? 418 ASN A N   1 
ATOM 3823 C CA  . ASN B 2 417 ? 151.422 111.667 147.952 1.00 69.75  ? 418 ASN A CA  1 
ATOM 3824 C C   . ASN B 2 417 ? 151.250 112.412 149.267 1.00 81.26  ? 418 ASN A C   1 
ATOM 3825 O O   . ASN B 2 417 ? 151.140 111.793 150.329 1.00 89.04  ? 418 ASN A O   1 
ATOM 3826 C CB  . ASN B 2 417 ? 150.081 111.087 147.503 1.00 72.79  ? 418 ASN A CB  1 
ATOM 3827 C CG  . ASN B 2 417 ? 150.148 110.478 146.124 1.00 79.64  ? 418 ASN A CG  1 
ATOM 3828 O OD1 . ASN B 2 417 ? 151.146 109.860 145.755 1.00 88.44  ? 418 ASN A OD1 1 
ATOM 3829 N ND2 . ASN B 2 417 ? 149.085 110.650 145.348 1.00 80.02  ? 418 ASN A ND2 1 
ATOM 3830 N N   . LEU B 2 418 ? 151.230 113.739 149.187 1.00 76.18  ? 419 LEU A N   1 
ATOM 3831 C CA  . LEU B 2 418 ? 150.903 114.597 150.314 1.00 66.66  ? 419 LEU A CA  1 
ATOM 3832 C C   . LEU B 2 418 ? 149.916 115.649 149.838 1.00 71.82  ? 419 LEU A C   1 
ATOM 3833 O O   . LEU B 2 418 ? 150.026 116.148 148.715 1.00 85.62  ? 419 LEU A O   1 
ATOM 3834 C CB  . LEU B 2 418 ? 152.150 115.262 150.899 1.00 55.06  ? 419 LEU A CB  1 
ATOM 3835 C CG  . LEU B 2 418 ? 152.010 115.891 152.284 1.00 54.14  ? 419 LEU A CG  1 
ATOM 3836 C CD1 . LEU B 2 418 ? 151.032 115.107 153.136 1.00 68.24  ? 419 LEU A CD1 1 
ATOM 3837 C CD2 . LEU B 2 418 ? 153.361 115.966 152.963 1.00 71.00  ? 419 LEU A CD2 1 
ATOM 3838 N N   . ASP B 2 419 ? 148.949 115.981 150.688 1.00 71.24  ? 420 ASP A N   1 
ATOM 3839 C CA  . ASP B 2 419 ? 147.880 116.893 150.292 1.00 70.22  ? 420 ASP A CA  1 
ATOM 3840 C C   . ASP B 2 419 ? 147.456 117.698 151.511 1.00 78.27  ? 420 ASP A C   1 
ATOM 3841 O O   . ASP B 2 419 ? 146.838 117.155 152.430 1.00 87.50  ? 420 ASP A O   1 
ATOM 3842 C CB  . ASP B 2 419 ? 146.700 116.125 149.705 1.00 70.46  ? 420 ASP A CB  1 
ATOM 3843 C CG  . ASP B 2 419 ? 145.765 117.011 148.915 1.00 85.70  ? 420 ASP A CG  1 
ATOM 3844 O OD1 . ASP B 2 419 ? 146.004 118.235 148.868 1.00 91.00  ? 420 ASP A OD1 1 
ATOM 3845 O OD2 . ASP B 2 419 ? 144.790 116.485 148.340 1.00 90.25  ? 420 ASP A OD2 1 
ATOM 3846 N N   . VAL B 2 420 ? 147.793 118.985 151.519 1.00 63.40  ? 421 VAL A N   1 
ATOM 3847 C CA  . VAL B 2 420 ? 147.379 119.891 152.584 1.00 63.27  ? 421 VAL A CA  1 
ATOM 3848 C C   . VAL B 2 420 ? 146.679 121.090 151.962 1.00 62.40  ? 421 VAL A C   1 
ATOM 3849 O O   . VAL B 2 420 ? 146.730 122.201 152.498 1.00 74.59  ? 421 VAL A O   1 
ATOM 3850 C CB  . VAL B 2 420 ? 148.572 120.329 153.448 1.00 54.67  ? 421 VAL A CB  1 
ATOM 3851 C CG1 . VAL B 2 420 ? 148.944 119.234 154.424 1.00 65.06  ? 421 VAL A CG1 1 
ATOM 3852 C CG2 . VAL B 2 420 ? 149.749 120.672 152.573 1.00 57.29  ? 421 VAL A CG2 1 
ATOM 3853 N N   . SER B 2 421 ? 146.036 120.873 150.819 1.00 59.21  ? 422 SER A N   1 
ATOM 3854 C CA  . SER B 2 421 ? 145.417 121.958 150.073 1.00 62.53  ? 422 SER A CA  1 
ATOM 3855 C C   . SER B 2 421 ? 144.280 122.604 150.856 1.00 69.46  ? 422 SER A C   1 
ATOM 3856 O O   . SER B 2 421 ? 143.585 121.955 151.641 1.00 85.74  ? 422 SER A O   1 
ATOM 3857 C CB  . SER B 2 421 ? 144.888 121.446 148.735 1.00 71.20  ? 422 SER A CB  1 
ATOM 3858 O OG  . SER B 2 421 ? 145.918 120.837 147.980 1.00 87.97  ? 422 SER A OG  1 
ATOM 3859 N N   . PHE B 2 422 ? 144.103 123.907 150.631 1.00 76.59  ? 423 PHE A N   1 
ATOM 3860 C CA  . PHE B 2 422 ? 142.978 124.678 151.161 1.00 74.63  ? 423 PHE A CA  1 
ATOM 3861 C C   . PHE B 2 422 ? 142.985 124.758 152.684 1.00 76.81  ? 423 PHE A C   1 
ATOM 3862 O O   . PHE B 2 422 ? 141.930 124.783 153.320 1.00 79.83  ? 423 PHE A O   1 
ATOM 3863 C CB  . PHE B 2 422 ? 141.641 124.127 150.660 1.00 71.84  ? 423 PHE A CB  1 
ATOM 3864 C CG  . PHE B 2 422 ? 141.449 124.274 149.182 1.00 75.61  ? 423 PHE A CG  1 
ATOM 3865 C CD1 . PHE B 2 422 ? 141.175 125.511 148.630 1.00 79.46  ? 423 PHE A CD1 1 
ATOM 3866 C CD2 . PHE B 2 422 ? 141.547 123.179 148.344 1.00 82.01  ? 423 PHE A CD2 1 
ATOM 3867 C CE1 . PHE B 2 422 ? 140.999 125.654 147.270 1.00 83.33  ? 423 PHE A CE1 1 
ATOM 3868 C CE2 . PHE B 2 422 ? 141.372 123.316 146.982 1.00 86.63  ? 423 PHE A CE2 1 
ATOM 3869 C CZ  . PHE B 2 422 ? 141.098 124.555 146.445 1.00 84.55  ? 423 PHE A CZ  1 
ATOM 3870 N N   . ASN B 2 423 ? 144.168 124.797 153.280 1.00 78.72  ? 424 ASN A N   1 
ATOM 3871 C CA  . ASN B 2 423 ? 144.328 125.158 154.677 1.00 74.94  ? 424 ASN A CA  1 
ATOM 3872 C C   . ASN B 2 423 ? 144.843 126.593 154.756 1.00 83.99  ? 424 ASN A C   1 
ATOM 3873 O O   . ASN B 2 423 ? 144.947 127.294 153.746 1.00 94.83  ? 424 ASN A O   1 
ATOM 3874 C CB  . ASN B 2 423 ? 145.261 124.165 155.367 1.00 82.57  ? 424 ASN A CB  1 
ATOM 3875 C CG  . ASN B 2 423 ? 144.764 122.741 155.276 1.00 82.67  ? 424 ASN A CG  1 
ATOM 3876 O OD1 . ASN B 2 423 ? 144.535 122.218 154.188 1.00 86.52  ? 424 ASN A OD1 1 
ATOM 3877 N ND2 . ASN B 2 423 ? 144.597 122.101 156.423 1.00 78.20  ? 424 ASN A ND2 1 
ATOM 3878 N N   . GLU B 2 424 ? 145.169 127.046 155.964 1.00 97.35  ? 425 GLU A N   1 
ATOM 3879 C CA  . GLU B 2 424 ? 145.818 128.341 156.165 1.00 100.42 ? 425 GLU A CA  1 
ATOM 3880 C C   . GLU B 2 424 ? 147.188 128.071 156.772 1.00 95.93  ? 425 GLU A C   1 
ATOM 3881 O O   . GLU B 2 424 ? 147.375 128.151 157.986 1.00 99.35  ? 425 GLU A O   1 
ATOM 3882 C CB  . GLU B 2 424 ? 144.976 129.278 157.050 1.00 102.72 ? 425 GLU A CB  1 
ATOM 3883 C CG  . GLU B 2 424 ? 144.277 128.605 158.217 1.00 103.16 ? 425 GLU A CG  1 
ATOM 3884 C CD  . GLU B 2 424 ? 142.840 128.253 157.905 1.00 108.53 ? 425 GLU A CD  1 
ATOM 3885 O OE1 . GLU B 2 424 ? 142.535 127.988 156.724 1.00 108.64 ? 425 GLU A OE1 1 
ATOM 3886 O OE2 . GLU B 2 424 ? 142.014 128.249 158.841 1.00 104.68 ? 425 GLU A OE2 1 
ATOM 3887 N N   . LEU B 2 425 ? 148.155 127.770 155.915 1.00 89.71  ? 426 LEU A N   1 
ATOM 3888 C CA  . LEU B 2 425 ? 149.503 127.433 156.345 1.00 95.68  ? 426 LEU A CA  1 
ATOM 3889 C C   . LEU B 2 425 ? 150.428 128.623 156.142 1.00 96.38  ? 426 LEU A C   1 
ATOM 3890 O O   . LEU B 2 425 ? 150.412 129.265 155.089 1.00 103.15 ? 426 LEU A O   1 
ATOM 3891 C CB  . LEU B 2 425 ? 150.038 126.223 155.578 1.00 94.15  ? 426 LEU A CB  1 
ATOM 3892 C CG  . LEU B 2 425 ? 149.504 124.855 155.997 1.00 87.25  ? 426 LEU A CG  1 
ATOM 3893 C CD1 . LEU B 2 425 ? 150.012 123.777 155.060 1.00 89.67  ? 426 LEU A CD1 1 
ATOM 3894 C CD2 . LEU B 2 425 ? 149.900 124.551 157.426 1.00 93.17  ? 426 LEU A CD2 1 
ATOM 3895 N N   . THR B 2 426 ? 151.232 128.915 157.162 1.00 100.87 ? 427 THR A N   1 
ATOM 3896 C CA  . THR B 2 426 ? 152.206 129.994 157.078 1.00 100.91 ? 427 THR A CA  1 
ATOM 3897 C C   . THR B 2 426 ? 153.577 129.489 156.644 1.00 102.98 ? 427 THR A C   1 
ATOM 3898 O O   . THR B 2 426 ? 154.271 130.163 155.876 1.00 106.47 ? 427 THR A O   1 
ATOM 3899 C CB  . THR B 2 426 ? 152.312 130.711 158.426 1.00 106.77 ? 427 THR A CB  1 
ATOM 3900 O OG1 . THR B 2 426 ? 151.020 131.196 158.811 1.00 105.28 ? 427 THR A OG1 1 
ATOM 3901 C CG2 . THR B 2 426 ? 153.278 131.883 158.339 1.00 105.75 ? 427 THR A CG2 1 
ATOM 3902 N N   . SER B 2 427 ? 153.974 128.308 157.112 1.00 96.18  ? 428 SER A N   1 
ATOM 3903 C CA  . SER B 2 427 ? 155.247 127.711 156.743 1.00 99.07  ? 428 SER A CA  1 
ATOM 3904 C C   . SER B 2 427 ? 155.041 126.226 156.483 1.00 100.30 ? 428 SER A C   1 
ATOM 3905 O O   . SER B 2 427 ? 154.063 125.627 156.935 1.00 100.68 ? 428 SER A O   1 
ATOM 3906 C CB  . SER B 2 427 ? 156.307 127.917 157.832 1.00 100.60 ? 428 SER A CB  1 
ATOM 3907 O OG  . SER B 2 427 ? 155.882 127.361 159.064 1.00 107.49 ? 428 SER A OG  1 
ATOM 3908 N N   . PHE B 2 428 ? 155.979 125.635 155.745 1.00 87.17  ? 429 PHE A N   1 
ATOM 3909 C CA  . PHE B 2 428 ? 155.904 124.222 155.414 1.00 86.09  ? 429 PHE A CA  1 
ATOM 3910 C C   . PHE B 2 428 ? 157.219 123.531 155.745 1.00 91.28  ? 429 PHE A C   1 
ATOM 3911 O O   . PHE B 2 428 ? 158.296 124.076 155.476 1.00 98.29  ? 429 PHE A O   1 
ATOM 3912 C CB  . PHE B 2 428 ? 155.573 124.025 153.929 1.00 81.79  ? 429 PHE A CB  1 
ATOM 3913 C CG  . PHE B 2 428 ? 155.047 122.660 153.604 1.00 84.66  ? 429 PHE A CG  1 
ATOM 3914 C CD1 . PHE B 2 428 ? 153.804 122.259 154.058 1.00 87.25  ? 429 PHE A CD1 1 
ATOM 3915 C CD2 . PHE B 2 428 ? 155.793 121.778 152.847 1.00 87.15  ? 429 PHE A CD2 1 
ATOM 3916 C CE1 . PHE B 2 428 ? 153.316 121.004 153.761 1.00 83.49  ? 429 PHE A CE1 1 
ATOM 3917 C CE2 . PHE B 2 428 ? 155.310 120.522 152.549 1.00 89.19  ? 429 PHE A CE2 1 
ATOM 3918 C CZ  . PHE B 2 428 ? 154.070 120.136 153.006 1.00 85.49  ? 429 PHE A CZ  1 
ATOM 3919 N N   . PRO B 2 429 ? 157.165 122.336 156.327 1.00 94.95  ? 430 PRO A N   1 
ATOM 3920 C CA  . PRO B 2 429 ? 158.399 121.614 156.652 1.00 89.83  ? 430 PRO A CA  1 
ATOM 3921 C C   . PRO B 2 429 ? 159.065 121.056 155.406 1.00 92.44  ? 430 PRO A C   1 
ATOM 3922 O O   . PRO B 2 429 ? 158.471 120.963 154.331 1.00 95.28  ? 430 PRO A O   1 
ATOM 3923 C CB  . PRO B 2 429 ? 157.925 120.486 157.576 1.00 90.20  ? 430 PRO A CB  1 
ATOM 3924 C CG  . PRO B 2 429 ? 156.523 120.846 157.964 1.00 101.36 ? 430 PRO A CG  1 
ATOM 3925 C CD  . PRO B 2 429 ? 155.974 121.637 156.829 1.00 99.20  ? 430 PRO A CD  1 
ATOM 3926 N N   . THR B 2 430 ? 160.330 120.682 155.570 1.00 102.20 ? 431 THR A N   1 
ATOM 3927 C CA  . THR B 2 430 ? 161.137 120.140 154.484 1.00 105.28 ? 431 THR A CA  1 
ATOM 3928 C C   . THR B 2 430 ? 161.683 118.753 154.772 1.00 106.01 ? 431 THR A C   1 
ATOM 3929 O O   . THR B 2 430 ? 161.727 117.915 153.869 1.00 109.67 ? 431 THR A O   1 
ATOM 3930 C CB  . THR B 2 430 ? 162.310 121.081 154.173 1.00 108.52 ? 431 THR A CB  1 
ATOM 3931 O OG1 . THR B 2 430 ? 163.285 120.993 155.219 1.00 107.68 ? 431 THR A OG1 1 
ATOM 3932 C CG2 . THR B 2 430 ? 161.830 122.519 154.055 1.00 105.94 ? 431 THR A CG2 1 
ATOM 3933 N N   . GLU B 2 431 ? 162.101 118.488 156.006 1.00 107.61 ? 432 GLU A N   1 
ATOM 3934 C CA  . GLU B 2 431 ? 162.753 117.226 156.327 1.00 109.19 ? 432 GLU A CA  1 
ATOM 3935 C C   . GLU B 2 431 ? 161.780 116.059 156.202 1.00 106.31 ? 432 GLU A C   1 
ATOM 3936 O O   . GLU B 2 431 ? 160.611 116.158 156.584 1.00 104.18 ? 432 GLU A O   1 
ATOM 3937 C CB  . GLU B 2 431 ? 163.336 117.283 157.740 1.00 108.20 ? 432 GLU A CB  1 
ATOM 3938 C CG  . GLU B 2 431 ? 163.352 115.956 158.481 1.00 111.39 ? 432 GLU A CG  1 
ATOM 3939 C CD  . GLU B 2 431 ? 164.463 115.034 158.015 1.00 116.33 ? 432 GLU A CD  1 
ATOM 3940 O OE1 . GLU B 2 431 ? 165.277 115.456 157.167 1.00 118.00 ? 432 GLU A OE1 1 
ATOM 3941 O OE2 . GLU B 2 431 ? 164.522 113.884 158.498 1.00 114.02 ? 432 GLU A OE2 1 
ATOM 3942 N N   . GLY B 2 432 ? 162.273 114.948 155.658 1.00 99.50  ? 433 GLY A N   1 
ATOM 3943 C CA  . GLY B 2 432 ? 161.496 113.735 155.533 1.00 101.21 ? 433 GLY A CA  1 
ATOM 3944 C C   . GLY B 2 432 ? 160.629 113.642 154.298 1.00 101.04 ? 433 GLY A C   1 
ATOM 3945 O O   . GLY B 2 432 ? 159.955 112.620 154.113 1.00 103.90 ? 433 GLY A O   1 
ATOM 3946 N N   . LEU B 2 433 ? 160.617 114.676 153.449 1.00 88.25  ? 434 LEU A N   1 
ATOM 3947 C CA  . LEU B 2 433 ? 159.740 114.702 152.249 1.00 92.00  ? 434 LEU A CA  1 
ATOM 3948 C C   . LEU B 2 433 ? 160.594 114.599 150.972 1.00 95.71  ? 434 LEU A C   1 
ATOM 3949 O O   . LEU B 2 433 ? 160.066 114.942 149.894 1.00 104.11 ? 434 LEU A O   1 
ATOM 3950 C CB  . LEU B 2 433 ? 158.889 115.973 152.288 1.00 94.44  ? 434 LEU A CB  1 
ATOM 3951 C CG  . LEU B 2 433 ? 157.704 115.968 153.260 1.00 91.41  ? 434 LEU A CG  1 
ATOM 3952 C CD1 . LEU B 2 433 ? 156.985 117.300 153.184 1.00 94.59  ? 434 LEU A CD1 1 
ATOM 3953 C CD2 . LEU B 2 433 ? 156.727 114.838 152.989 1.00 92.50  ? 434 LEU A CD2 1 
ATOM 3954 N N   . ASN B 2 434 ? 161.848 114.133 151.052 1.00 99.94  ? 435 ASN A N   1 
ATOM 3955 C CA  . ASN B 2 434 ? 162.688 114.068 149.861 1.00 106.06 ? 435 ASN A CA  1 
ATOM 3956 C C   . ASN B 2 434 ? 162.126 113.095 148.833 1.00 111.88 ? 435 ASN A C   1 
ATOM 3957 O O   . ASN B 2 434 ? 162.095 113.397 147.634 1.00 115.39 ? 435 ASN A O   1 
ATOM 3958 C CB  . ASN B 2 434 ? 164.115 113.681 150.246 1.00 102.89 ? 435 ASN A CB  1 
ATOM 3959 C CG  . ASN B 2 434 ? 164.158 112.690 151.387 1.00 111.74 ? 435 ASN A CG  1 
ATOM 3960 O OD1 . ASN B 2 434 ? 163.786 111.528 151.228 1.00 115.14 ? 435 ASN A OD1 1 
ATOM 3961 N ND2 . ASN B 2 434 ? 164.613 113.144 152.548 1.00 112.50 ? 435 ASN A ND2 1 
ATOM 3962 N N   . GLY B 2 435 ? 161.671 111.929 149.277 1.00 93.11  ? 436 GLY A N   1 
ATOM 3963 C CA  . GLY B 2 435 ? 161.138 110.943 148.358 1.00 84.72  ? 436 GLY A CA  1 
ATOM 3964 C C   . GLY B 2 435 ? 159.650 111.086 148.123 1.00 84.22  ? 436 GLY A C   1 
ATOM 3965 O O   . GLY B 2 435 ? 158.923 110.090 148.098 1.00 92.15  ? 436 GLY A O   1 
ATOM 3966 N N   . LEU B 2 436 ? 159.151 112.330 148.038 1.00 74.91  ? 437 LEU A N   1 
ATOM 3967 C CA  . LEU B 2 436 ? 157.702 112.612 147.853 1.00 83.06  ? 437 LEU A CA  1 
ATOM 3968 C C   . LEU B 2 436 ? 157.447 112.882 146.368 1.00 85.73  ? 437 LEU A C   1 
ATOM 3969 O O   . LEU B 2 436 ? 157.965 113.899 145.872 1.00 103.94 ? 437 LEU A O   1 
ATOM 3970 C CB  . LEU B 2 436 ? 157.283 113.785 148.738 1.00 83.38  ? 437 LEU A CB  1 
ATOM 3971 C CG  . LEU B 2 436 ? 155.788 114.111 148.768 1.00 82.25  ? 437 LEU A CG  1 
ATOM 3972 C CD1 . LEU B 2 436 ? 155.026 113.189 149.695 1.00 88.43  ? 437 LEU A CD1 1 
ATOM 3973 C CD2 . LEU B 2 436 ? 155.581 115.550 149.182 1.00 86.78  ? 437 LEU A CD2 1 
ATOM 3974 N N   . ASN B 2 437 ? 156.677 112.026 145.694 1.00 85.54  ? 438 ASN A N   1 
ATOM 3975 C CA  . ASN B 2 437 ? 156.419 112.160 144.263 1.00 89.38  ? 438 ASN A CA  1 
ATOM 3976 C C   . ASN B 2 437 ? 155.433 113.283 143.969 1.00 93.04  ? 438 ASN A C   1 
ATOM 3977 O O   . ASN B 2 437 ? 155.584 114.002 142.976 1.00 106.22 ? 438 ASN A O   1 
ATOM 3978 C CB  . ASN B 2 437 ? 155.905 110.839 143.694 1.00 95.98  ? 438 ASN A CB  1 
ATOM 3979 C CG  . ASN B 2 437 ? 156.972 109.767 143.660 1.00 105.33 ? 438 ASN A CG  1 
ATOM 3980 O OD1 . ASN B 2 437 ? 158.131 110.018 143.988 1.00 107.17 ? 438 ASN A OD1 1 
ATOM 3981 N ND2 . ASN B 2 437 ? 156.587 108.562 143.257 1.00 103.73 ? 438 ASN A ND2 1 
ATOM 3982 N N   . GLN B 2 438 ? 154.417 113.449 144.810 1.00 83.60  ? 439 GLN A N   1 
ATOM 3983 C CA  . GLN B 2 438 ? 153.352 114.410 144.563 1.00 85.09  ? 439 GLN A CA  1 
ATOM 3984 C C   . GLN B 2 438 ? 153.155 115.304 145.777 1.00 91.96  ? 439 GLN A C   1 
ATOM 3985 O O   . GLN B 2 438 ? 153.241 114.844 146.920 1.00 94.94  ? 439 GLN A O   1 
ATOM 3986 C CB  . GLN B 2 438 ? 152.039 113.701 144.224 1.00 82.60  ? 439 GLN A CB  1 
ATOM 3987 C CG  . GLN B 2 438 ? 150.937 114.633 143.760 1.00 87.60  ? 439 GLN A CG  1 
ATOM 3988 C CD  . GLN B 2 438 ? 149.909 113.935 142.898 1.00 97.53  ? 439 GLN A CD  1 
ATOM 3989 O OE1 . GLN B 2 438 ? 148.828 114.467 142.647 1.00 98.62  ? 439 GLN A OE1 1 
ATOM 3990 N NE2 . GLN B 2 438 ? 150.239 112.735 142.439 1.00 97.88  ? 439 GLN A NE2 1 
ATOM 3991 N N   . LEU B 2 439 ? 152.886 116.581 145.521 1.00 85.83  ? 440 LEU A N   1 
ATOM 3992 C CA  . LEU B 2 439 ? 152.647 117.559 146.570 1.00 74.04  ? 440 LEU A CA  1 
ATOM 3993 C C   . LEU B 2 439 ? 151.559 118.516 146.110 1.00 78.55  ? 440 LEU A C   1 
ATOM 3994 O O   . LEU B 2 439 ? 151.520 118.902 144.940 1.00 97.95  ? 440 LEU A O   1 
ATOM 3995 C CB  . LEU B 2 439 ? 153.923 118.333 146.909 1.00 69.32  ? 440 LEU A CB  1 
ATOM 3996 C CG  . LEU B 2 439 ? 153.862 119.219 148.148 1.00 71.45  ? 440 LEU A CG  1 
ATOM 3997 C CD1 . LEU B 2 439 ? 153.250 118.450 149.302 1.00 78.25  ? 440 LEU A CD1 1 
ATOM 3998 C CD2 . LEU B 2 439 ? 155.245 119.721 148.511 1.00 76.72  ? 440 LEU A CD2 1 
ATOM 3999 N N   . LYS B 2 440 ? 150.675 118.894 147.031 1.00 70.64  ? 441 LYS A N   1 
ATOM 4000 C CA  . LYS B 2 440 ? 149.561 119.785 146.717 1.00 75.07  ? 441 LYS A CA  1 
ATOM 4001 C C   . LYS B 2 440 ? 149.431 120.808 147.835 1.00 83.64  ? 441 LYS A C   1 
ATOM 4002 O O   . LYS B 2 440 ? 149.037 120.462 148.952 1.00 89.55  ? 441 LYS A O   1 
ATOM 4003 C CB  . LYS B 2 440 ? 148.262 119.003 146.535 1.00 70.50  ? 441 LYS A CB  1 
ATOM 4004 C CG  . LYS B 2 440 ? 148.031 118.533 145.111 1.00 78.10  ? 441 LYS A CG  1 
ATOM 4005 C CD  . LYS B 2 440 ? 146.644 117.946 144.937 1.00 82.86  ? 441 LYS A CD  1 
ATOM 4006 C CE  . LYS B 2 440 ? 146.617 116.483 145.341 1.00 86.24  ? 441 LYS A CE  1 
ATOM 4007 N NZ  . LYS B 2 440 ? 147.557 115.668 144.525 1.00 89.82  ? 441 LYS A NZ  1 
ATOM 4008 N N   . LEU B 2 441 ? 149.759 122.065 147.533 1.00 77.46  ? 442 LEU A N   1 
ATOM 4009 C CA  . LEU B 2 441 ? 149.738 123.140 148.517 1.00 63.79  ? 442 LEU A CA  1 
ATOM 4010 C C   . LEU B 2 441 ? 148.782 124.264 148.143 1.00 66.93  ? 442 LEU A C   1 
ATOM 4011 O O   . LEU B 2 441 ? 148.824 125.328 148.770 1.00 82.97  ? 442 LEU A O   1 
ATOM 4012 C CB  . LEU B 2 441 ? 151.148 123.709 148.708 1.00 56.18  ? 442 LEU A CB  1 
ATOM 4013 C CG  . LEU B 2 441 ? 151.979 123.231 149.897 1.00 66.58  ? 442 LEU A CG  1 
ATOM 4014 C CD1 . LEU B 2 441 ? 151.939 121.731 150.004 1.00 73.51  ? 442 LEU A CD1 1 
ATOM 4015 C CD2 . LEU B 2 441 ? 153.413 123.701 149.754 1.00 80.90  ? 442 LEU A CD2 1 
ATOM 4016 N N   . VAL B 2 442 ? 147.922 124.061 147.144 1.00 61.37  ? 443 VAL A N   1 
ATOM 4017 C CA  . VAL B 2 442 ? 147.065 125.136 146.661 1.00 74.53  ? 443 VAL A CA  1 
ATOM 4018 C C   . VAL B 2 442 ? 146.073 125.547 147.744 1.00 80.15  ? 443 VAL A C   1 
ATOM 4019 O O   . VAL B 2 442 ? 145.717 124.760 148.630 1.00 91.33  ? 443 VAL A O   1 
ATOM 4020 C CB  . VAL B 2 442 ? 146.341 124.704 145.372 1.00 78.53  ? 443 VAL A CB  1 
ATOM 4021 C CG1 . VAL B 2 442 ? 145.191 123.765 145.688 1.00 79.74  ? 443 VAL A CG1 1 
ATOM 4022 C CG2 . VAL B 2 442 ? 145.852 125.915 144.595 1.00 83.92  ? 443 VAL A CG2 1 
ATOM 4023 N N   . GLY B 2 443 ? 145.638 126.805 147.687 1.00 78.54  ? 444 GLY A N   1 
ATOM 4024 C CA  . GLY B 2 443 ? 144.643 127.323 148.599 1.00 78.40  ? 444 GLY A CA  1 
ATOM 4025 C C   . GLY B 2 443 ? 145.179 127.914 149.885 1.00 83.05  ? 444 GLY A C   1 
ATOM 4026 O O   . GLY B 2 443 ? 144.402 128.508 150.642 1.00 86.92  ? 444 GLY A O   1 
ATOM 4027 N N   . ASN B 2 444 ? 146.476 127.777 150.159 1.00 81.52  ? 445 ASN A N   1 
ATOM 4028 C CA  . ASN B 2 444 ? 147.084 128.350 151.358 1.00 80.89  ? 445 ASN A CA  1 
ATOM 4029 C C   . ASN B 2 444 ? 147.684 129.702 150.984 1.00 90.56  ? 445 ASN A C   1 
ATOM 4030 O O   . ASN B 2 444 ? 148.886 129.847 150.767 1.00 88.43  ? 445 ASN A O   1 
ATOM 4031 C CB  . ASN B 2 444 ? 148.128 127.404 151.939 1.00 78.97  ? 445 ASN A CB  1 
ATOM 4032 C CG  . ASN B 2 444 ? 147.647 125.974 151.994 1.00 80.68  ? 445 ASN A CG  1 
ATOM 4033 O OD1 . ASN B 2 444 ? 147.099 125.456 151.024 1.00 82.04  ? 445 ASN A OD1 1 
ATOM 4034 N ND2 . ASN B 2 444 ? 147.846 125.327 153.132 1.00 82.71  ? 445 ASN A ND2 1 
ATOM 4035 N N   . PHE B 2 445 ? 146.813 130.709 150.915 1.00 93.79  ? 446 PHE A N   1 
ATOM 4036 C CA  . PHE B 2 445 ? 147.223 132.025 150.442 1.00 85.72  ? 446 PHE A CA  1 
ATOM 4037 C C   . PHE B 2 445 ? 148.200 132.713 151.385 1.00 87.30  ? 446 PHE A C   1 
ATOM 4038 O O   . PHE B 2 445 ? 148.920 133.618 150.953 1.00 96.05  ? 446 PHE A O   1 
ATOM 4039 C CB  . PHE B 2 445 ? 145.993 132.902 150.224 1.00 81.51  ? 446 PHE A CB  1 
ATOM 4040 C CG  . PHE B 2 445 ? 145.138 132.459 149.077 1.00 89.11  ? 446 PHE A CG  1 
ATOM 4041 C CD1 . PHE B 2 445 ? 145.675 132.329 147.809 1.00 90.09  ? 446 PHE A CD1 1 
ATOM 4042 C CD2 . PHE B 2 445 ? 143.801 132.158 149.267 1.00 90.15  ? 446 PHE A CD2 1 
ATOM 4043 C CE1 . PHE B 2 445 ? 144.895 131.916 146.750 1.00 93.37  ? 446 PHE A CE1 1 
ATOM 4044 C CE2 . PHE B 2 445 ? 143.015 131.744 148.211 1.00 95.24  ? 446 PHE A CE2 1 
ATOM 4045 C CZ  . PHE B 2 445 ? 143.563 131.624 146.950 1.00 97.98  ? 446 PHE A CZ  1 
ATOM 4046 N N   . LYS B 2 446 ? 148.246 132.310 152.653 1.00 85.05  ? 447 LYS A N   1 
ATOM 4047 C CA  . LYS B 2 446 ? 149.206 132.885 153.585 1.00 86.82  ? 447 LYS A CA  1 
ATOM 4048 C C   . LYS B 2 446 ? 150.596 132.280 153.451 1.00 91.78  ? 447 LYS A C   1 
ATOM 4049 O O   . LYS B 2 446 ? 151.537 132.793 154.064 1.00 93.72  ? 447 LYS A O   1 
ATOM 4050 C CB  . LYS B 2 446 ? 148.715 132.716 155.024 1.00 90.55  ? 447 LYS A CB  1 
ATOM 4051 C CG  . LYS B 2 446 ? 147.437 133.468 155.341 1.00 91.77  ? 447 LYS A CG  1 
ATOM 4052 C CD  . LYS B 2 446 ? 147.098 133.365 156.819 1.00 94.60  ? 447 LYS A CD  1 
ATOM 4053 C CE  . LYS B 2 446 ? 145.724 133.939 157.112 1.00 94.11  ? 447 LYS A CE  1 
ATOM 4054 N NZ  . LYS B 2 446 ? 144.644 133.129 156.486 1.00 93.63  ? 447 LYS A NZ  1 
ATOM 4055 N N   . LEU B 2 447 ? 150.747 131.210 152.675 1.00 85.59  ? 448 LEU A N   1 
ATOM 4056 C CA  . LEU B 2 447 ? 152.041 130.556 152.488 1.00 85.67  ? 448 LEU A CA  1 
ATOM 4057 C C   . LEU B 2 447 ? 152.822 131.337 151.441 1.00 90.92  ? 448 LEU A C   1 
ATOM 4058 O O   . LEU B 2 447 ? 152.793 131.029 150.249 1.00 95.78  ? 448 LEU A O   1 
ATOM 4059 C CB  . LEU B 2 447 ? 151.851 129.101 152.081 1.00 82.61  ? 448 LEU A CB  1 
ATOM 4060 C CG  . LEU B 2 447 ? 153.113 128.243 151.996 1.00 82.13  ? 448 LEU A CG  1 
ATOM 4061 C CD1 . LEU B 2 447 ? 153.712 128.035 153.372 1.00 83.70  ? 448 LEU A CD1 1 
ATOM 4062 C CD2 . LEU B 2 447 ? 152.797 126.915 151.344 1.00 85.66  ? 448 LEU A CD2 1 
ATOM 4063 N N   . LYS B 2 448 ? 153.529 132.368 151.895 1.00 96.77  ? 449 LYS A N   1 
ATOM 4064 C CA  . LYS B 2 448 ? 154.293 133.243 151.019 1.00 97.20  ? 449 LYS A CA  1 
ATOM 4065 C C   . LYS B 2 448 ? 155.759 132.851 150.912 1.00 96.22  ? 449 LYS A C   1 
ATOM 4066 O O   . LYS B 2 448 ? 156.530 133.570 150.274 1.00 100.91 ? 449 LYS A O   1 
ATOM 4067 C CB  . LYS B 2 448 ? 154.186 134.693 151.500 1.00 97.02  ? 449 LYS A CB  1 
ATOM 4068 C CG  . LYS B 2 448 ? 152.772 135.142 151.816 1.00 97.38  ? 449 LYS A CG  1 
ATOM 4069 C CD  . LYS B 2 448 ? 152.175 135.928 150.664 1.00 88.58  ? 449 LYS A CD  1 
ATOM 4070 C CE  . LYS B 2 448 ? 150.793 136.446 151.011 1.00 90.05  ? 449 LYS A CE  1 
ATOM 4071 N NZ  . LYS B 2 448 ? 150.823 137.358 152.186 1.00 92.05  ? 449 LYS A NZ  1 
ATOM 4072 N N   . GLU B 2 449 ? 156.168 131.746 151.527 1.00 104.12 ? 450 GLU A N   1 
ATOM 4073 C CA  . GLU B 2 449 ? 157.560 131.335 151.466 1.00 106.25 ? 450 GLU A CA  1 
ATOM 4074 C C   . GLU B 2 449 ? 157.850 130.642 150.137 1.00 106.76 ? 450 GLU A C   1 
ATOM 4075 O O   . GLU B 2 449 ? 156.972 130.467 149.289 1.00 107.24 ? 450 GLU A O   1 
ATOM 4076 C CB  . GLU B 2 449 ? 157.898 130.434 152.649 1.00 111.98 ? 450 GLU A CB  1 
ATOM 4077 C CG  . GLU B 2 449 ? 157.830 131.138 153.992 1.00 113.57 ? 450 GLU A CG  1 
ATOM 4078 C CD  . GLU B 2 449 ? 157.763 130.171 155.155 1.00 120.19 ? 450 GLU A CD  1 
ATOM 4079 O OE1 . GLU B 2 449 ? 158.285 129.044 155.026 1.00 120.01 ? 450 GLU A OE1 1 
ATOM 4080 O OE2 . GLU B 2 449 ? 157.189 130.542 156.201 1.00 119.83 ? 450 GLU A OE2 1 
ATOM 4081 N N   . ALA B 2 450 ? 159.104 130.240 149.954 1.00 104.37 ? 451 ALA A N   1 
ATOM 4082 C CA  . ALA B 2 450 ? 159.556 129.580 148.738 1.00 106.47 ? 451 ALA A CA  1 
ATOM 4083 C C   . ALA B 2 450 ? 160.048 128.181 149.075 1.00 108.50 ? 451 ALA A C   1 
ATOM 4084 O O   . ALA B 2 450 ? 160.812 128.002 150.029 1.00 108.87 ? 451 ALA A O   1 
ATOM 4085 C CB  . ALA B 2 450 ? 160.665 130.383 148.055 1.00 108.77 ? 451 ALA A CB  1 
ATOM 4086 N N   . LEU B 2 451 ? 159.613 127.197 148.293 1.00 96.72  ? 452 LEU A N   1 
ATOM 4087 C CA  . LEU B 2 451 ? 160.011 125.810 148.498 1.00 93.91  ? 452 LEU A CA  1 
ATOM 4088 C C   . LEU B 2 451 ? 161.266 125.522 147.685 1.00 97.34  ? 452 LEU A C   1 
ATOM 4089 O O   . LEU B 2 451 ? 161.247 125.608 146.453 1.00 100.25 ? 452 LEU A O   1 
ATOM 4090 C CB  . LEU B 2 451 ? 158.887 124.858 148.098 1.00 87.34  ? 452 LEU A CB  1 
ATOM 4091 C CG  . LEU B 2 451 ? 157.462 125.326 148.383 1.00 93.51  ? 452 LEU A CG  1 
ATOM 4092 C CD1 . LEU B 2 451 ? 156.466 124.443 147.659 1.00 93.07  ? 452 LEU A CD1 1 
ATOM 4093 C CD2 . LEU B 2 451 ? 157.195 125.327 149.876 1.00 98.07  ? 452 LEU A CD2 1 
ATOM 4094 N N   . ALA B 2 452 ? 162.351 125.180 148.373 1.00 102.49 ? 453 ALA A N   1 
ATOM 4095 C CA  . ALA B 2 452 ? 163.595 124.864 147.690 1.00 102.33 ? 453 ALA A CA  1 
ATOM 4096 C C   . ALA B 2 452 ? 163.491 123.517 146.988 1.00 104.61 ? 453 ALA A C   1 
ATOM 4097 O O   . ALA B 2 452 ? 163.019 122.533 147.562 1.00 112.42 ? 453 ALA A O   1 
ATOM 4098 C CB  . ALA B 2 452 ? 164.758 124.853 148.681 1.00 103.43 ? 453 ALA A CB  1 
ATOM 4099 N N   . ALA B 2 453 ? 163.938 123.477 145.732 1.00 111.53 ? 454 ALA A N   1 
ATOM 4100 C CA  . ALA B 2 453 ? 163.903 122.239 144.965 1.00 111.70 ? 454 ALA A CA  1 
ATOM 4101 C C   . ALA B 2 453 ? 164.947 121.232 145.423 1.00 109.99 ? 454 ALA A C   1 
ATOM 4102 O O   . ALA B 2 453 ? 164.904 120.080 144.980 1.00 110.64 ? 454 ALA A O   1 
ATOM 4103 C CB  . ALA B 2 453 ? 164.094 122.536 143.478 1.00 112.13 ? 454 ALA A CB  1 
ATOM 4104 N N   . LYS B 2 454 ? 165.881 121.636 146.285 1.00 112.12 ? 455 LYS A N   1 
ATOM 4105 C CA  . LYS B 2 454 ? 166.884 120.699 146.778 1.00 112.97 ? 455 LYS A CA  1 
ATOM 4106 C C   . LYS B 2 454 ? 166.250 119.615 147.639 1.00 117.18 ? 455 LYS A C   1 
ATOM 4107 O O   . LYS B 2 454 ? 166.677 118.455 147.606 1.00 119.64 ? 455 LYS A O   1 
ATOM 4108 C CB  . LYS B 2 454 ? 167.958 121.448 147.564 1.00 110.39 ? 455 LYS A CB  1 
ATOM 4109 C CG  . LYS B 2 454 ? 168.676 122.516 146.760 1.00 117.52 ? 455 LYS A CG  1 
ATOM 4110 C CD  . LYS B 2 454 ? 169.209 121.960 145.450 1.00 116.89 ? 455 LYS A CD  1 
ATOM 4111 C CE  . LYS B 2 454 ? 170.358 120.993 145.683 1.00 116.15 ? 455 LYS A CE  1 
ATOM 4112 N NZ  . LYS B 2 454 ? 170.870 120.427 144.405 1.00 112.58 ? 455 LYS A NZ  1 
ATOM 4113 N N   . ASP B 2 455 ? 165.232 119.975 148.422 1.00 120.02 ? 456 ASP A N   1 
ATOM 4114 C CA  . ASP B 2 455 ? 164.600 119.004 149.308 1.00 120.36 ? 456 ASP A CA  1 
ATOM 4115 C C   . ASP B 2 455 ? 163.808 117.968 148.520 1.00 116.73 ? 456 ASP A C   1 
ATOM 4116 O O   . ASP B 2 455 ? 163.947 116.762 148.748 1.00 119.99 ? 456 ASP A O   1 
ATOM 4117 C CB  . ASP B 2 455 ? 163.699 119.724 150.309 1.00 118.09 ? 456 ASP A CB  1 
ATOM 4118 C CG  . ASP B 2 455 ? 164.367 120.935 150.924 1.00 124.40 ? 456 ASP A CG  1 
ATOM 4119 O OD1 . ASP B 2 455 ? 165.605 120.912 151.083 1.00 125.49 ? 456 ASP A OD1 1 
ATOM 4120 O OD2 . ASP B 2 455 ? 163.657 121.910 151.246 1.00 127.94 ? 456 ASP A OD2 1 
ATOM 4121 N N   . PHE B 2 456 ? 162.936 118.428 147.617 1.00 95.58  ? 457 PHE A N   1 
ATOM 4122 C CA  . PHE B 2 456 ? 162.064 117.512 146.835 1.00 100.75 ? 457 PHE A CA  1 
ATOM 4123 C C   . PHE B 2 456 ? 162.816 117.064 145.583 1.00 107.05 ? 457 PHE A C   1 
ATOM 4124 O O   . PHE B 2 456 ? 162.459 117.531 144.481 1.00 113.15 ? 457 PHE A O   1 
ATOM 4125 C CB  . PHE B 2 456 ? 160.762 118.267 146.566 1.00 102.11 ? 457 PHE A CB  1 
ATOM 4126 C CG  . PHE B 2 456 ? 160.009 118.728 147.805 1.00 103.31 ? 457 PHE A CG  1 
ATOM 4127 C CD1 . PHE B 2 456 ? 159.171 117.860 148.494 1.00 106.96 ? 457 PHE A CD1 1 
ATOM 4128 C CD2 . PHE B 2 456 ? 160.127 120.033 148.265 1.00 104.40 ? 457 PHE A CD2 1 
ATOM 4129 C CE1 . PHE B 2 456 ? 158.475 118.286 149.612 1.00 103.96 ? 457 PHE A CE1 1 
ATOM 4130 C CE2 . PHE B 2 456 ? 159.432 120.452 149.388 1.00 105.92 ? 457 PHE A CE2 1 
ATOM 4131 C CZ  . PHE B 2 456 ? 158.609 119.578 150.059 1.00 104.14 ? 457 PHE A CZ  1 
ATOM 4132 N N   . VAL B 2 457 ? 163.810 116.178 145.724 1.00 105.14 ? 458 VAL A N   1 
ATOM 4133 C CA  . VAL B 2 457 ? 164.625 115.725 144.603 1.00 102.92 ? 458 VAL A CA  1 
ATOM 4134 C C   . VAL B 2 457 ? 163.876 114.759 143.692 1.00 104.51 ? 458 VAL A C   1 
ATOM 4135 O O   . VAL B 2 457 ? 164.289 114.556 142.544 1.00 107.72 ? 458 VAL A O   1 
ATOM 4136 C CB  . VAL B 2 457 ? 165.923 115.079 145.118 1.00 103.06 ? 458 VAL A CB  1 
ATOM 4137 C CG1 . VAL B 2 457 ? 165.664 113.661 145.601 1.00 103.74 ? 458 VAL A CG1 1 
ATOM 4138 C CG2 . VAL B 2 457 ? 167.002 115.104 144.044 1.00 104.74 ? 458 VAL A CG2 1 
ATOM 4139 N N   . ASN B 2 458 ? 162.778 114.165 144.160 1.00 93.83  ? 459 ASN A N   1 
ATOM 4140 C CA  . ASN B 2 458 ? 162.036 113.181 143.381 1.00 89.70  ? 459 ASN A CA  1 
ATOM 4141 C C   . ASN B 2 458 ? 160.604 113.601 143.074 1.00 89.55  ? 459 ASN A C   1 
ATOM 4142 O O   . ASN B 2 458 ? 159.817 112.778 142.593 1.00 87.42  ? 459 ASN A O   1 
ATOM 4143 C CB  . ASN B 2 458 ? 162.007 111.838 144.117 1.00 91.04  ? 459 ASN A CB  1 
ATOM 4144 C CG  . ASN B 2 458 ? 161.902 110.659 143.173 1.00 99.94  ? 459 ASN A CG  1 
ATOM 4145 O OD1 . ASN B 2 458 ? 161.640 110.822 141.982 1.00 104.66 ? 459 ASN A OD1 1 
ATOM 4146 N ND2 . ASN B 2 458 ? 162.106 109.459 143.702 1.00 102.75 ? 459 ASN A ND2 1 
ATOM 4147 N N   . LEU B 2 459 ? 160.259 114.859 143.366 1.00 88.60  ? 460 LEU A N   1 
ATOM 4148 C CA  . LEU B 2 459 ? 158.872 115.348 143.160 1.00 93.63  ? 460 LEU A CA  1 
ATOM 4149 C C   . LEU B 2 459 ? 158.559 115.321 141.663 1.00 90.10  ? 460 LEU A C   1 
ATOM 4150 O O   . LEU B 2 459 ? 159.477 115.640 140.881 1.00 97.80  ? 460 LEU A O   1 
ATOM 4151 C CB  . LEU B 2 459 ? 158.662 116.739 143.753 1.00 90.32  ? 460 LEU A CB  1 
ATOM 4152 C CG  . LEU B 2 459 ? 157.215 117.240 143.747 1.00 85.85  ? 460 LEU A CG  1 
ATOM 4153 C CD1 . LEU B 2 459 ? 156.908 118.120 144.941 1.00 89.17  ? 460 LEU A CD1 1 
ATOM 4154 C CD2 . LEU B 2 459 ? 156.920 117.970 142.457 1.00 88.91  ? 460 LEU A CD2 1 
ATOM 4155 N N   . ARG B 2 460 ? 157.337 114.935 141.291 1.00 96.12  ? 461 ARG A N   1 
ATOM 4156 C CA  . ARG B 2 460 ? 156.880 114.892 139.906 1.00 97.73  ? 461 ARG A CA  1 
ATOM 4157 C C   . ARG B 2 460 ? 155.754 115.865 139.601 1.00 99.56  ? 461 ARG A C   1 
ATOM 4158 O O   . ARG B 2 460 ? 155.773 116.508 138.550 1.00 106.65 ? 461 ARG A O   1 
ATOM 4159 C CB  . ARG B 2 460 ? 156.406 113.469 139.592 1.00 104.09 ? 461 ARG A CB  1 
ATOM 4160 C CG  . ARG B 2 460 ? 157.508 112.425 139.617 1.00 105.76 ? 461 ARG A CG  1 
ATOM 4161 C CD  . ARG B 2 460 ? 158.160 112.275 138.254 1.00 108.57 ? 461 ARG A CD  1 
ATOM 4162 N NE  . ARG B 2 460 ? 159.283 111.347 138.289 1.00 110.15 ? 461 ARG A NE  1 
ATOM 4163 C CZ  . ARG B 2 460 ? 160.557 111.709 138.217 1.00 110.77 ? 461 ARG A CZ  1 
ATOM 4164 N NH1 . ARG B 2 460 ? 160.909 112.979 138.108 1.00 108.35 ? 461 ARG A NH1 1 
ATOM 4165 N NH2 . ARG B 2 460 ? 161.500 110.773 138.258 1.00 108.39 ? 461 ARG A NH2 1 
ATOM 4166 N N   . SER B 2 461 ? 154.767 115.990 140.485 1.00 93.53  ? 462 SER A N   1 
ATOM 4167 C CA  . SER B 2 461 ? 153.644 116.894 140.287 1.00 97.00  ? 462 SER A CA  1 
ATOM 4168 C C   . SER B 2 461 ? 153.488 117.783 141.511 1.00 98.33  ? 462 SER A C   1 
ATOM 4169 O O   . SER B 2 461 ? 153.461 117.293 142.643 1.00 106.41 ? 462 SER A O   1 
ATOM 4170 C CB  . SER B 2 461 ? 152.345 116.126 140.034 1.00 97.66  ? 462 SER A CB  1 
ATOM 4171 O OG  . SER B 2 461 ? 151.221 116.976 140.161 1.00 98.11  ? 462 SER A OG  1 
ATOM 4172 N N   . LEU B 2 462 ? 153.376 119.089 141.279 1.00 95.31  ? 463 LEU A N   1 
ATOM 4173 C CA  . LEU B 2 462 ? 153.352 120.064 142.357 1.00 87.78  ? 463 LEU A CA  1 
ATOM 4174 C C   . LEU B 2 462 ? 152.184 121.019 142.167 1.00 86.50  ? 463 LEU A C   1 
ATOM 4175 O O   . LEU B 2 462 ? 151.783 121.319 141.041 1.00 95.31  ? 463 LEU A O   1 
ATOM 4176 C CB  . LEU B 2 462 ? 154.665 120.856 142.420 1.00 83.83  ? 463 LEU A CB  1 
ATOM 4177 C CG  . LEU B 2 462 ? 154.798 121.915 143.512 1.00 83.42  ? 463 LEU A CG  1 
ATOM 4178 C CD1 . LEU B 2 462 ? 155.047 121.268 144.860 1.00 91.82  ? 463 LEU A CD1 1 
ATOM 4179 C CD2 . LEU B 2 462 ? 155.900 122.896 143.170 1.00 91.17  ? 463 LEU A CD2 1 
ATOM 4180 N N   . SER B 2 463 ? 151.638 121.486 143.287 1.00 78.81  ? 464 SER A N   1 
ATOM 4181 C CA  . SER B 2 463 ? 150.615 122.524 143.291 1.00 84.00  ? 464 SER A CA  1 
ATOM 4182 C C   . SER B 2 463 ? 150.960 123.509 144.395 1.00 91.49  ? 464 SER A C   1 
ATOM 4183 O O   . SER B 2 463 ? 151.146 123.106 145.546 1.00 101.36 ? 464 SER A O   1 
ATOM 4184 C CB  . SER B 2 463 ? 149.221 121.935 143.508 1.00 84.17  ? 464 SER A CB  1 
ATOM 4185 O OG  . SER B 2 463 ? 148.226 122.935 143.399 1.00 85.32  ? 464 SER A OG  1 
ATOM 4186 N N   . VAL B 2 464 ? 151.052 124.789 144.050 1.00 84.02  ? 465 VAL A N   1 
ATOM 4187 C CA  . VAL B 2 464 ? 151.455 125.809 145.014 1.00 78.22  ? 465 VAL A CA  1 
ATOM 4188 C C   . VAL B 2 464 ? 150.451 126.955 144.989 1.00 78.39  ? 465 VAL A C   1 
ATOM 4189 O O   . VAL B 2 464 ? 149.804 127.187 143.958 1.00 82.94  ? 465 VAL A O   1 
ATOM 4190 C CB  . VAL B 2 464 ? 152.881 126.306 144.728 1.00 75.82  ? 465 VAL A CB  1 
ATOM 4191 C CG1 . VAL B 2 464 ? 153.894 125.307 145.243 1.00 78.41  ? 465 VAL A CG1 1 
ATOM 4192 C CG2 . VAL B 2 464 ? 153.073 126.526 143.245 1.00 87.23  ? 465 VAL A CG2 1 
ATOM 4193 N N   . PRO B 2 465 ? 150.273 127.680 146.096 1.00 69.24  ? 466 PRO A N   1 
ATOM 4194 C CA  . PRO B 2 465 ? 149.292 128.778 146.099 1.00 70.14  ? 466 PRO A CA  1 
ATOM 4195 C C   . PRO B 2 465 ? 149.620 129.902 145.133 1.00 84.57  ? 466 PRO A C   1 
ATOM 4196 O O   . PRO B 2 465 ? 148.699 130.497 144.560 1.00 83.19  ? 466 PRO A O   1 
ATOM 4197 C CB  . PRO B 2 465 ? 149.319 129.261 147.555 1.00 73.92  ? 466 PRO A CB  1 
ATOM 4198 C CG  . PRO B 2 465 ? 150.650 128.838 148.071 1.00 70.65  ? 466 PRO A CG  1 
ATOM 4199 C CD  . PRO B 2 465 ? 150.951 127.540 147.395 1.00 70.11  ? 466 PRO A CD  1 
ATOM 4200 N N   . TYR B 2 466 ? 150.897 130.216 144.933 1.00 96.64  ? 467 TYR A N   1 
ATOM 4201 C CA  . TYR B 2 466 ? 151.310 131.315 144.074 1.00 86.92  ? 467 TYR A CA  1 
ATOM 4202 C C   . TYR B 2 466 ? 152.209 130.798 142.962 1.00 90.03  ? 467 TYR A C   1 
ATOM 4203 O O   . TYR B 2 466 ? 153.023 129.894 143.176 1.00 94.12  ? 467 TYR A O   1 
ATOM 4204 C CB  . TYR B 2 466 ? 152.039 132.398 144.872 1.00 80.09  ? 467 TYR A CB  1 
ATOM 4205 C CG  . TYR B 2 466 ? 151.171 133.077 145.903 1.00 83.64  ? 467 TYR A CG  1 
ATOM 4206 C CD1 . TYR B 2 466 ? 149.955 133.642 145.549 1.00 86.31  ? 467 TYR A CD1 1 
ATOM 4207 C CD2 . TYR B 2 466 ? 151.567 133.153 147.229 1.00 85.99  ? 467 TYR A CD2 1 
ATOM 4208 C CE1 . TYR B 2 466 ? 149.158 134.262 146.486 1.00 86.27  ? 467 TYR A CE1 1 
ATOM 4209 C CE2 . TYR B 2 466 ? 150.777 133.772 148.174 1.00 86.66  ? 467 TYR A CE2 1 
ATOM 4210 C CZ  . TYR B 2 466 ? 149.574 134.324 147.797 1.00 90.03  ? 467 TYR A CZ  1 
ATOM 4211 O OH  . TYR B 2 466 ? 148.783 134.942 148.736 1.00 96.57  ? 467 TYR A OH  1 
ATOM 4212 N N   . ALA B 2 467 ? 152.059 131.384 141.773 1.00 91.35  ? 468 ALA A N   1 
ATOM 4213 C CA  . ALA B 2 467 ? 152.823 130.941 140.613 1.00 90.55  ? 468 ALA A CA  1 
ATOM 4214 C C   . ALA B 2 467 ? 154.316 131.204 140.753 1.00 86.46  ? 468 ALA A C   1 
ATOM 4215 O O   . ALA B 2 467 ? 155.111 130.555 140.068 1.00 92.69  ? 468 ALA A O   1 
ATOM 4216 C CB  . ALA B 2 467 ? 152.296 131.620 139.350 1.00 87.24  ? 468 ALA A CB  1 
ATOM 4217 N N   . TYR B 2 468 ? 154.718 132.137 141.616 1.00 84.45  ? 469 TYR A N   1 
ATOM 4218 C CA  . TYR B 2 468 ? 156.136 132.447 141.749 1.00 87.42  ? 469 TYR A CA  1 
ATOM 4219 C C   . TYR B 2 468 ? 156.892 131.389 142.536 1.00 91.48  ? 469 TYR A C   1 
ATOM 4220 O O   . TYR B 2 468 ? 158.123 131.338 142.454 1.00 96.25  ? 469 TYR A O   1 
ATOM 4221 C CB  . TYR B 2 468 ? 156.318 133.813 142.408 1.00 93.12  ? 469 TYR A CB  1 
ATOM 4222 C CG  . TYR B 2 468 ? 155.759 134.954 141.596 1.00 92.72  ? 469 TYR A CG  1 
ATOM 4223 C CD1 . TYR B 2 468 ? 156.412 135.404 140.460 1.00 90.45  ? 469 TYR A CD1 1 
ATOM 4224 C CD2 . TYR B 2 468 ? 154.579 135.583 141.965 1.00 90.49  ? 469 TYR A CD2 1 
ATOM 4225 C CE1 . TYR B 2 468 ? 155.908 136.444 139.713 1.00 87.68  ? 469 TYR A CE1 1 
ATOM 4226 C CE2 . TYR B 2 468 ? 154.067 136.625 141.224 1.00 84.68  ? 469 TYR A CE2 1 
ATOM 4227 C CZ  . TYR B 2 468 ? 154.736 137.051 140.099 1.00 86.61  ? 469 TYR A CZ  1 
ATOM 4228 O OH  . TYR B 2 468 ? 154.231 138.090 139.356 1.00 100.55 ? 469 TYR A OH  1 
ATOM 4229 N N   . GLN B 2 469 ? 156.191 130.546 143.294 1.00 94.09  ? 470 GLN A N   1 
ATOM 4230 C CA  . GLN B 2 469 ? 156.875 129.523 144.076 1.00 93.18  ? 470 GLN A CA  1 
ATOM 4231 C C   . GLN B 2 469 ? 157.385 128.392 143.196 1.00 95.12  ? 470 GLN A C   1 
ATOM 4232 O O   . GLN B 2 469 ? 158.384 127.749 143.533 1.00 100.57 ? 470 GLN A O   1 
ATOM 4233 C CB  . GLN B 2 469 ? 155.944 128.978 145.155 1.00 89.71  ? 470 GLN A CB  1 
ATOM 4234 C CG  . GLN B 2 469 ? 155.828 129.878 146.365 1.00 95.85  ? 470 GLN A CG  1 
ATOM 4235 C CD  . GLN B 2 469 ? 154.486 129.761 147.048 1.00 96.53  ? 470 GLN A CD  1 
ATOM 4236 O OE1 . GLN B 2 469 ? 153.458 129.592 146.396 1.00 99.36  ? 470 GLN A OE1 1 
ATOM 4237 N NE2 . GLN B 2 469 ? 154.487 129.854 148.371 1.00 98.07  ? 470 GLN A NE2 1 
ATOM 4238 N N   . CYS B 2 470 ? 156.720 128.138 142.071 1.00 105.79 ? 471 CYS A N   1 
ATOM 4239 C CA  . CYS B 2 470 ? 157.132 127.072 141.171 1.00 109.81 ? 471 CYS A CA  1 
ATOM 4240 C C   . CYS B 2 470 ? 158.206 127.508 140.184 1.00 109.34 ? 471 CYS A C   1 
ATOM 4241 O O   . CYS B 2 470 ? 158.674 126.678 139.399 1.00 107.02 ? 471 CYS A O   1 
ATOM 4242 C CB  . CYS B 2 470 ? 155.919 126.536 140.409 1.00 106.82 ? 471 CYS A CB  1 
ATOM 4243 S SG  . CYS B 2 470 ? 155.407 127.542 139.005 1.00 126.85 ? 471 CYS A SG  1 
ATOM 4244 N N   . CYS B 2 471 ? 158.604 128.782 140.201 1.00 119.94 ? 472 CYS A N   1 
ATOM 4245 C CA  . CYS B 2 471 ? 159.646 129.243 139.290 1.00 118.57 ? 472 CYS A CA  1 
ATOM 4246 C C   . CYS B 2 471 ? 160.994 128.631 139.646 1.00 115.42 ? 472 CYS A C   1 
ATOM 4247 O O   . CYS B 2 471 ? 161.699 128.107 138.777 1.00 122.57 ? 472 CYS A O   1 
ATOM 4248 C CB  . CYS B 2 471 ? 159.727 130.769 139.315 1.00 119.95 ? 472 CYS A CB  1 
ATOM 4249 S SG  . CYS B 2 471 ? 158.505 131.601 138.282 1.00 128.38 ? 472 CYS A SG  1 
ATOM 4250 N N   . ALA B 2 472 ? 161.370 128.687 140.924 1.00 101.41 ? 473 ALA A N   1 
ATOM 4251 C CA  . ALA B 2 472 ? 162.639 128.114 141.352 1.00 107.69 ? 473 ALA A CA  1 
ATOM 4252 C C   . ALA B 2 472 ? 162.628 126.594 141.318 1.00 104.05 ? 473 ALA A C   1 
ATOM 4253 O O   . ALA B 2 472 ? 163.694 125.976 141.394 1.00 101.23 ? 473 ALA A O   1 
ATOM 4254 C CB  . ALA B 2 472 ? 162.987 128.598 142.760 1.00 107.93 ? 473 ALA A CB  1 
ATOM 4255 N N   . PHE B 2 473 ? 161.439 125.989 141.238 1.00 107.78 ? 474 PHE A N   1 
ATOM 4256 C CA  . PHE B 2 473 ? 161.296 124.510 141.281 1.00 111.39 ? 474 PHE A CA  1 
ATOM 4257 C C   . PHE B 2 473 ? 161.604 123.893 139.929 1.00 114.42 ? 474 PHE A C   1 
ATOM 4258 O O   . PHE B 2 473 ? 162.571 123.106 139.873 1.00 112.93 ? 474 PHE A O   1 
ATOM 4259 C CB  . PHE B 2 473 ? 159.863 124.192 141.717 1.00 107.36 ? 474 PHE A CB  1 
ATOM 4260 C CG  . PHE B 2 473 ? 159.755 123.111 142.779 1.00 103.23 ? 474 PHE A CG  1 
ATOM 4261 C CD1 . PHE B 2 473 ? 159.375 121.818 142.442 1.00 108.00 ? 474 PHE A CD1 1 
ATOM 4262 C CD2 . PHE B 2 473 ? 160.033 123.395 144.109 1.00 107.72 ? 474 PHE A CD2 1 
ATOM 4263 C CE1 . PHE B 2 473 ? 159.272 120.840 143.415 1.00 112.54 ? 474 PHE A CE1 1 
ATOM 4264 C CE2 . PHE B 2 473 ? 159.932 122.412 145.076 1.00 114.48 ? 474 PHE A CE2 1 
ATOM 4265 C CZ  . PHE B 2 473 ? 159.552 121.140 144.726 1.00 115.34 ? 474 PHE A CZ  1 
ATOM 4266 N N   . TRP B 2 474 ? 160.848 124.230 138.877 1.00 141.44 ? 475 TRP A N   1 
ATOM 4267 C CA  . TRP B 2 474 ? 160.983 123.588 137.576 1.00 143.11 ? 475 TRP A CA  1 
ATOM 4268 C C   . TRP B 2 474 ? 162.104 124.183 136.738 1.00 142.27 ? 475 TRP A C   1 
ATOM 4269 O O   . TRP B 2 474 ? 162.557 123.533 135.790 1.00 144.09 ? 475 TRP A O   1 
ATOM 4270 C CB  . TRP B 2 474 ? 159.662 123.672 136.814 1.00 141.43 ? 475 TRP A CB  1 
ATOM 4271 N N   . GLY B 2 475 ? 162.560 125.390 137.067 1.00 151.69 ? 476 GLY A N   1 
ATOM 4272 C CA  . GLY B 2 475 ? 163.590 126.102 136.299 1.00 154.12 ? 476 GLY A CA  1 
ATOM 4273 C C   . GLY B 2 475 ? 163.063 126.250 134.872 1.00 158.81 ? 476 GLY A C   1 
ATOM 4274 O O   . GLY B 2 475 ? 161.944 126.757 134.691 1.00 156.60 ? 476 GLY A O   1 
ATOM 4275 N N   . CYS B 2 476 ? 163.806 125.832 133.847 1.00 171.44 ? 477 CYS A N   1 
ATOM 4276 C CA  . CYS B 2 476 ? 163.356 125.975 132.469 1.00 167.22 ? 477 CYS A CA  1 
ATOM 4277 C C   . CYS B 2 476 ? 162.258 124.990 132.087 1.00 168.50 ? 477 CYS A C   1 
ATOM 4278 O O   . CYS B 2 476 ? 161.592 125.202 131.068 1.00 166.85 ? 477 CYS A O   1 
ATOM 4279 C CB  . CYS B 2 476 ? 164.540 125.814 131.511 1.00 163.80 ? 477 CYS A CB  1 
ATOM 4280 N N   . ASP B 2 477 ? 162.058 123.923 132.866 1.00 171.21 ? 478 ASP A N   1 
ATOM 4281 C CA  . ASP B 2 477 ? 161.041 122.935 132.519 1.00 168.47 ? 478 ASP A CA  1 
ATOM 4282 C C   . ASP B 2 477 ? 159.640 123.532 132.572 1.00 169.27 ? 478 ASP A C   1 
ATOM 4283 O O   . ASP B 2 477 ? 158.818 123.285 131.682 1.00 168.02 ? 478 ASP A O   1 
ATOM 4284 C CB  . ASP B 2 477 ? 161.144 121.725 133.448 1.00 163.48 ? 478 ASP A CB  1 
ATOM 4285 N N   . SER B 2 478 ? 159.351 124.323 133.601 1.00 153.86 ? 479 SER A N   1 
ATOM 4286 C CA  . SER B 2 478 ? 158.033 124.929 133.760 1.00 148.68 ? 479 SER A CA  1 
ATOM 4287 C C   . SER B 2 478 ? 158.094 126.140 134.684 1.00 145.49 ? 479 SER A C   1 
ATOM 4288 O O   . SER B 2 478 ? 159.154 126.481 135.209 1.00 141.75 ? 479 SER A O   1 
ATOM 4289 C CB  . SER B 2 478 ? 157.038 123.906 134.292 1.00 143.97 ? 479 SER A CB  1 
ATOM 4290 N N   . SER B 2 516 ? 166.428 117.778 132.260 1.00 171.85 ? 516 SER A N   1 
ATOM 4291 C CA  . SER B 2 516 ? 167.322 116.819 132.897 1.00 172.33 ? 516 SER A CA  1 
ATOM 4292 C C   . SER B 2 516 ? 166.532 115.776 133.678 1.00 172.74 ? 516 SER A C   1 
ATOM 4293 O O   . SER B 2 516 ? 166.729 115.613 134.883 1.00 171.56 ? 516 SER A O   1 
ATOM 4294 C CB  . SER B 2 516 ? 168.305 117.534 133.809 1.00 170.45 ? 516 SER A CB  1 
ATOM 4295 N N   . GLN B 2 517 ? 165.640 115.075 132.975 1.00 169.76 ? 517 GLN A N   1 
ATOM 4296 C CA  . GLN B 2 517 ? 164.801 114.031 133.566 1.00 169.36 ? 517 GLN A CA  1 
ATOM 4297 C C   . GLN B 2 517 ? 164.007 114.561 134.758 1.00 170.07 ? 517 GLN A C   1 
ATOM 4298 O O   . GLN B 2 517 ? 163.842 113.880 135.772 1.00 167.70 ? 517 GLN A O   1 
ATOM 4299 C CB  . GLN B 2 517 ? 165.635 112.811 133.967 1.00 165.47 ? 517 GLN A CB  1 
ATOM 4300 N N   . ILE B 2 518 ? 163.511 115.792 134.636 1.00 156.18 ? 518 ILE A N   1 
ATOM 4301 C CA  . ILE B 2 518 ? 162.714 116.394 135.699 1.00 154.01 ? 518 ILE A CA  1 
ATOM 4302 C C   . ILE B 2 518 ? 161.223 116.154 135.476 1.00 152.88 ? 518 ILE A C   1 
ATOM 4303 O O   . ILE B 2 518 ? 160.557 115.535 136.312 1.00 150.44 ? 518 ILE A O   1 
ATOM 4304 C CB  . ILE B 2 518 ? 163.012 117.894 135.794 1.00 150.86 ? 518 ILE A CB  1 
ATOM 4305 N N   . ILE B 2 519 ? 160.696 116.631 134.346 1.00 144.49 ? 519 ILE A N   1 
ATOM 4306 C CA  . ILE B 2 519 ? 159.289 116.449 133.981 1.00 144.75 ? 519 ILE A CA  1 
ATOM 4307 C C   . ILE B 2 519 ? 158.350 116.920 135.089 1.00 146.20 ? 519 ILE A C   1 
ATOM 4308 O O   . ILE B 2 519 ? 157.252 116.385 135.261 1.00 145.06 ? 519 ILE A O   1 
ATOM 4309 C CB  . ILE B 2 519 ? 158.998 114.993 133.612 1.00 142.63 ? 519 ILE A CB  1 
ATOM 4310 N N   . ILE B 2 520 ? 158.773 117.926 135.847 1.00 128.89 ? 520 ILE A N   1 
ATOM 4311 C CA  . ILE B 2 520 ? 157.984 118.423 136.968 1.00 123.91 ? 520 ILE A CA  1 
ATOM 4312 C C   . ILE B 2 520 ? 156.860 119.298 136.435 1.00 123.08 ? 520 ILE A C   1 
ATOM 4313 O O   . ILE B 2 520 ? 157.095 120.227 135.653 1.00 128.08 ? 520 ILE A O   1 
ATOM 4314 C CB  . ILE B 2 520 ? 158.870 119.194 137.958 1.00 122.21 ? 520 ILE A CB  1 
ATOM 4315 C CG1 . ILE B 2 520 ? 159.815 118.235 138.682 1.00 123.57 ? 520 ILE A CG1 1 
ATOM 4316 C CG2 . ILE B 2 520 ? 158.016 119.947 138.962 1.00 119.77 ? 520 ILE A CG2 1 
ATOM 4317 C CD1 . ILE B 2 520 ? 161.149 118.848 139.041 1.00 122.45 ? 520 ILE A CD1 1 
ATOM 4318 N N   . HIS B 2 521 ? 155.634 119.004 136.857 1.00 107.91 ? 521 HIS A N   1 
ATOM 4319 C CA  . HIS B 2 521 ? 154.452 119.738 136.429 1.00 108.92 ? 521 HIS A CA  1 
ATOM 4320 C C   . HIS B 2 521 ? 153.891 120.518 137.609 1.00 111.09 ? 521 HIS A C   1 
ATOM 4321 O O   . HIS B 2 521 ? 153.593 119.936 138.657 1.00 117.39 ? 521 HIS A O   1 
ATOM 4322 C CB  . HIS B 2 521 ? 153.396 118.785 135.868 1.00 107.98 ? 521 HIS A CB  1 
ATOM 4323 C CG  . HIS B 2 521 ? 152.116 119.459 135.484 1.00 113.18 ? 521 HIS A CG  1 
ATOM 4324 N ND1 . HIS B 2 521 ? 151.073 119.634 136.367 1.00 114.24 ? 521 HIS A ND1 1 
ATOM 4325 C CD2 . HIS B 2 521 ? 151.711 119.999 134.311 1.00 112.65 ? 521 HIS A CD2 1 
ATOM 4326 C CE1 . HIS B 2 521 ? 150.080 120.253 135.755 1.00 115.69 ? 521 HIS A CE1 1 
ATOM 4327 N NE2 . HIS B 2 521 ? 150.441 120.487 134.507 1.00 113.65 ? 521 HIS A NE2 1 
ATOM 4328 N N   . CYS B 2 522 ? 153.743 121.828 137.433 1.00 118.17 ? 522 CYS A N   1 
ATOM 4329 C CA  . CYS B 2 522 ? 153.275 122.722 138.484 1.00 115.46 ? 522 CYS A CA  1 
ATOM 4330 C C   . CYS B 2 522 ? 151.929 123.307 138.085 1.00 116.06 ? 522 CYS A C   1 
ATOM 4331 O O   . CYS B 2 522 ? 151.764 123.778 136.956 1.00 120.43 ? 522 CYS A O   1 
ATOM 4332 C CB  . CYS B 2 522 ? 154.289 123.834 138.742 1.00 114.47 ? 522 CYS A CB  1 
ATOM 4333 S SG  . CYS B 2 522 ? 155.953 123.229 139.102 1.00 131.60 ? 522 CYS A SG  1 
ATOM 4334 N N   . THR B 2 523 ? 150.972 123.273 139.014 1.00 120.26 ? 523 THR A N   1 
ATOM 4335 C CA  . THR B 2 523 ? 149.605 123.675 138.686 1.00 123.90 ? 523 THR A CA  1 
ATOM 4336 C C   . THR B 2 523 ? 149.493 125.137 138.269 1.00 126.56 ? 523 THR A C   1 
ATOM 4337 O O   . THR B 2 523 ? 148.918 125.403 137.199 1.00 127.06 ? 523 THR A O   1 
ATOM 4338 C CB  . THR B 2 523 ? 148.677 123.347 139.862 1.00 127.75 ? 523 THR A CB  1 
ATOM 4339 O OG1 . THR B 2 523 ? 148.311 121.963 139.812 1.00 130.81 ? 523 THR A OG1 1 
ATOM 4340 C CG2 . THR B 2 523 ? 147.416 124.198 139.808 1.00 124.47 ? 523 THR A CG2 1 
ATOM 4341 N N   . PRO B 2 524 ? 150.004 126.128 139.027 1.00 122.25 ? 524 PRO A N   1 
ATOM 4342 C CA  . PRO B 2 524 ? 149.923 127.509 138.535 1.00 118.82 ? 524 PRO A CA  1 
ATOM 4343 C C   . PRO B 2 524 ? 151.088 127.846 137.619 1.00 120.02 ? 524 PRO A C   1 
ATOM 4344 O O   . PRO B 2 524 ? 152.249 127.832 138.042 1.00 120.39 ? 524 PRO A O   1 
ATOM 4345 C CB  . PRO B 2 524 ? 149.941 128.343 139.819 1.00 110.67 ? 524 PRO A CB  1 
ATOM 4346 C CG  . PRO B 2 524 ? 150.647 127.494 140.821 1.00 117.09 ? 524 PRO A CG  1 
ATOM 4347 C CD  . PRO B 2 524 ? 150.686 126.067 140.332 1.00 115.89 ? 524 PRO A CD  1 
ATOM 4348 N N   . SER B 2 525 ? 150.788 128.153 136.364 1.00 117.96 ? 525 SER A N   1 
ATOM 4349 C CA  . SER B 2 525 ? 151.811 128.370 135.355 1.00 116.13 ? 525 SER A CA  1 
ATOM 4350 C C   . SER B 2 525 ? 152.326 129.805 135.397 1.00 118.28 ? 525 SER A C   1 
ATOM 4351 O O   . SER B 2 525 ? 151.672 130.715 135.909 1.00 121.81 ? 525 SER A O   1 
ATOM 4352 C CB  . SER B 2 525 ? 151.265 128.052 133.964 1.00 119.84 ? 525 SER A CB  1 
ATOM 4353 O OG  . SER B 2 525 ? 150.064 128.762 133.718 1.00 120.86 ? 525 SER A OG  1 
ATOM 4354 N N   . THR B 2 526 ? 153.521 129.992 134.846 1.00 112.15 ? 526 THR A N   1 
ATOM 4355 C CA  . THR B 2 526 ? 154.148 131.304 134.717 1.00 116.98 ? 526 THR A CA  1 
ATOM 4356 C C   . THR B 2 526 ? 154.233 131.624 133.226 1.00 118.99 ? 526 THR A C   1 
ATOM 4357 O O   . THR B 2 526 ? 155.249 131.371 132.578 1.00 119.57 ? 526 THR A O   1 
ATOM 4358 C CB  . THR B 2 526 ? 155.523 131.320 135.374 1.00 116.12 ? 526 THR A CB  1 
ATOM 4359 O OG1 . THR B 2 526 ? 156.477 130.707 134.499 1.00 114.65 ? 526 THR A OG1 1 
ATOM 4360 C CG2 . THR B 2 526 ? 155.488 130.552 136.683 1.00 111.24 ? 526 THR A CG2 1 
ATOM 4361 N N   . GLY B 2 527 ? 153.156 132.191 132.689 1.00 128.69 ? 527 GLY A N   1 
ATOM 4362 C CA  . GLY B 2 527 ? 153.075 132.477 131.269 1.00 129.46 ? 527 GLY A CA  1 
ATOM 4363 C C   . GLY B 2 527 ? 153.481 133.887 130.895 1.00 130.62 ? 527 GLY A C   1 
ATOM 4364 O O   . GLY B 2 527 ? 152.732 134.590 130.209 1.00 133.14 ? 527 GLY A O   1 
ATOM 4365 N N   . ALA B 2 528 ? 154.652 134.318 131.362 1.00 117.71 ? 528 ALA A N   1 
ATOM 4366 C CA  . ALA B 2 528 ? 155.271 135.612 131.087 1.00 116.21 ? 528 ALA A CA  1 
ATOM 4367 C C   . ALA B 2 528 ? 154.514 136.775 131.714 1.00 115.27 ? 528 ALA A C   1 
ATOM 4368 O O   . ALA B 2 528 ? 154.987 137.915 131.634 1.00 112.03 ? 528 ALA A O   1 
ATOM 4369 C CB  . ALA B 2 528 ? 155.437 135.881 129.584 1.00 118.67 ? 528 ALA A CB  1 
ATOM 4370 N N   . PHE B 2 529 ? 153.361 136.534 132.332 1.00 117.80 ? 529 PHE A N   1 
ATOM 4371 C CA  . PHE B 2 529 ? 152.728 137.508 133.207 1.00 114.25 ? 529 PHE A CA  1 
ATOM 4372 C C   . PHE B 2 529 ? 153.042 137.241 134.668 1.00 114.85 ? 529 PHE A C   1 
ATOM 4373 O O   . PHE B 2 529 ? 152.570 137.975 135.538 1.00 119.08 ? 529 PHE A O   1 
ATOM 4374 C CB  . PHE B 2 529 ? 151.214 137.525 132.988 1.00 114.64 ? 529 PHE A CB  1 
ATOM 4375 C CG  . PHE B 2 529 ? 150.733 138.720 132.218 1.00 118.72 ? 529 PHE A CG  1 
ATOM 4376 C CD1 . PHE B 2 529 ? 150.683 138.696 130.836 1.00 121.07 ? 529 PHE A CD1 1 
ATOM 4377 C CD2 . PHE B 2 529 ? 150.343 139.872 132.876 1.00 122.90 ? 529 PHE A CD2 1 
ATOM 4378 C CE1 . PHE B 2 529 ? 150.244 139.797 130.126 1.00 121.37 ? 529 PHE A CE1 1 
ATOM 4379 C CE2 . PHE B 2 529 ? 149.904 140.975 132.171 1.00 119.61 ? 529 PHE A CE2 1 
ATOM 4380 C CZ  . PHE B 2 529 ? 149.855 140.937 130.795 1.00 117.23 ? 529 PHE A CZ  1 
ATOM 4381 N N   . LYS B 2 530 ? 153.807 136.191 134.950 1.00 94.17  ? 530 LYS A N   1 
ATOM 4382 C CA  . LYS B 2 530 ? 154.397 135.943 136.263 1.00 94.55  ? 530 LYS A CA  1 
ATOM 4383 C C   . LYS B 2 530 ? 155.870 135.667 136.004 1.00 96.90  ? 530 LYS A C   1 
ATOM 4384 O O   . LYS B 2 530 ? 156.312 134.511 136.028 1.00 104.70 ? 530 LYS A O   1 
ATOM 4385 C CB  . LYS B 2 530 ? 153.714 134.781 136.983 1.00 97.02  ? 530 LYS A CB  1 
ATOM 4386 C CG  . LYS B 2 530 ? 152.214 134.946 137.150 1.00 97.42  ? 530 LYS A CG  1 
ATOM 4387 C CD  . LYS B 2 530 ? 151.888 135.973 138.218 1.00 94.34  ? 530 LYS A CD  1 
ATOM 4388 C CE  . LYS B 2 530 ? 150.394 136.050 138.468 1.00 97.04  ? 530 LYS A CE  1 
ATOM 4389 N NZ  . LYS B 2 530 ? 150.084 136.171 139.918 1.00 98.40  ? 530 LYS A NZ  1 
ATOM 4390 N N   . PRO B 2 531 ? 156.655 136.708 135.732 1.00 92.34  ? 531 PRO A N   1 
ATOM 4391 C CA  . PRO B 2 531 ? 158.027 136.497 135.254 1.00 95.32  ? 531 PRO A CA  1 
ATOM 4392 C C   . PRO B 2 531 ? 158.876 135.750 136.270 1.00 99.18  ? 531 PRO A C   1 
ATOM 4393 O O   . PRO B 2 531 ? 158.713 135.904 137.481 1.00 103.15 ? 531 PRO A O   1 
ATOM 4394 C CB  . PRO B 2 531 ? 158.547 137.921 135.027 1.00 97.92  ? 531 PRO A CB  1 
ATOM 4395 C CG  . PRO B 2 531 ? 157.330 138.784 134.978 1.00 99.78  ? 531 PRO A CG  1 
ATOM 4396 C CD  . PRO B 2 531 ? 156.333 138.135 135.873 1.00 96.85  ? 531 PRO A CD  1 
ATOM 4397 N N   . CYS B 2 532 ? 159.791 134.931 135.757 1.00 105.19 ? 532 CYS A N   1 
ATOM 4398 C CA  . CYS B 2 532 ? 160.672 134.141 136.605 1.00 105.84 ? 532 CYS A CA  1 
ATOM 4399 C C   . CYS B 2 532 ? 161.966 134.893 136.898 1.00 109.98 ? 532 CYS A C   1 
ATOM 4400 O O   . CYS B 2 532 ? 162.376 134.994 138.057 1.00 116.56 ? 532 CYS A O   1 
ATOM 4401 C CB  . CYS B 2 532 ? 161.073 132.851 135.885 1.00 110.98 ? 532 CYS A CB  1 
ATOM 4402 S SG  . CYS B 2 532 ? 159.737 132.080 134.943 1.00 131.30 ? 532 CYS A SG  1 
ATOM 4403 N N   . GLU B 2 533 ? 162.570 135.501 135.886 1.00 109.00 ? 533 GLU A N   1 
ATOM 4404 C CA  . GLU B 2 533 ? 163.874 136.170 136.075 1.00 113.16 ? 533 GLU A CA  1 
ATOM 4405 C C   . GLU B 2 533 ? 163.708 137.687 135.999 1.00 115.79 ? 533 GLU A C   1 
ATOM 4406 O O   . GLU B 2 533 ? 163.960 138.311 137.022 1.00 115.08 ? 533 GLU A O   1 
ATOM 4407 C CB  . GLU B 2 533 ? 164.817 135.593 135.036 1.00 113.92 ? 533 GLU A CB  1 
ATOM 4408 C CG  . GLU B 2 533 ? 165.328 134.212 135.422 1.00 116.12 ? 533 GLU A CG  1 
ATOM 4409 C CD  . GLU B 2 533 ? 165.280 133.229 134.274 1.00 121.09 ? 533 GLU A CD  1 
ATOM 4410 O OE1 . GLU B 2 533 ? 164.170 132.948 133.780 1.00 121.28 ? 533 GLU A OE1 1 
ATOM 4411 O OE2 . GLU B 2 533 ? 166.358 132.753 133.873 1.00 120.75 ? 533 GLU A OE2 1 
ATOM 4412 N N   . TYR B 2 534 ? 163.317 138.263 134.857 1.00 109.67 ? 534 TYR A N   1 
ATOM 4413 C CA  . TYR B 2 534 ? 163.205 139.707 134.701 1.00 107.62 ? 534 TYR A CA  1 
ATOM 4414 C C   . TYR B 2 534 ? 161.762 140.156 134.525 1.00 107.69 ? 534 TYR A C   1 
ATOM 4415 O O   . TYR B 2 534 ? 161.002 139.537 133.774 1.00 103.59 ? 534 TYR A O   1 
ATOM 4416 C CB  . TYR B 2 534 ? 164.012 140.008 133.438 1.00 105.90 ? 534 TYR A CB  1 
ATOM 4417 C CG  . TYR B 2 534 ? 165.267 139.178 133.314 1.00 104.07 ? 534 TYR A CG  1 
ATOM 4418 C CD1 . TYR B 2 534 ? 166.399 139.481 134.056 1.00 103.05 ? 534 TYR A CD1 1 
ATOM 4419 C CD2 . TYR B 2 534 ? 165.318 138.088 132.458 1.00 106.75 ? 534 TYR A CD2 1 
ATOM 4420 C CE1 . TYR B 2 534 ? 167.547 138.724 133.947 1.00 105.56 ? 534 TYR A CE1 1 
ATOM 4421 C CE2 . TYR B 2 534 ? 166.461 137.325 132.343 1.00 109.27 ? 534 TYR A CE2 1 
ATOM 4422 C CZ  . TYR B 2 534 ? 167.572 137.647 133.090 1.00 109.64 ? 534 TYR A CZ  1 
ATOM 4423 O OH  . TYR B 2 534 ? 168.714 136.889 132.978 1.00 108.28 ? 534 TYR A OH  1 
ATOM 4424 N N   . LEU B 2 535 ? 161.393 141.236 135.215 1.00 92.75  ? 535 LEU A N   1 
ATOM 4425 C CA  . LEU B 2 535 ? 160.018 141.718 135.160 1.00 89.78  ? 535 LEU A CA  1 
ATOM 4426 C C   . LEU B 2 535 ? 159.685 142.295 133.790 1.00 94.16  ? 535 LEU A C   1 
ATOM 4427 O O   . LEU B 2 535 ? 158.656 141.956 133.197 1.00 93.31  ? 535 LEU A O   1 
ATOM 4428 C CB  . LEU B 2 535 ? 159.785 142.762 136.251 1.00 80.76  ? 535 LEU A CB  1 
ATOM 4429 C CG  . LEU B 2 535 ? 158.535 143.624 136.089 1.00 80.27  ? 535 LEU A CG  1 
ATOM 4430 C CD1 . LEU B 2 535 ? 157.282 142.779 136.209 1.00 88.34  ? 535 LEU A CD1 1 
ATOM 4431 C CD2 . LEU B 2 535 ? 158.524 144.740 137.111 1.00 85.13  ? 535 LEU A CD2 1 
ATOM 4432 N N   . LEU B 2 536 ? 160.545 143.173 133.270 1.00 99.80  ? 536 LEU A N   1 
ATOM 4433 C CA  . LEU B 2 536 ? 160.249 143.812 131.992 1.00 95.38  ? 536 LEU A CA  1 
ATOM 4434 C C   . LEU B 2 536 ? 160.447 142.847 130.831 1.00 97.85  ? 536 LEU A C   1 
ATOM 4435 O O   . LEU B 2 536 ? 159.639 142.820 129.896 1.00 102.90 ? 536 LEU A O   1 
ATOM 4436 C CB  . LEU B 2 536 ? 161.112 145.060 131.817 1.00 91.13  ? 536 LEU A CB  1 
ATOM 4437 C CG  . LEU B 2 536 ? 160.757 146.233 132.734 1.00 90.45  ? 536 LEU A CG  1 
ATOM 4438 C CD1 . LEU B 2 536 ? 161.393 147.518 132.241 1.00 93.62  ? 536 LEU A CD1 1 
ATOM 4439 C CD2 . LEU B 2 536 ? 159.253 146.391 132.840 1.00 92.80  ? 536 LEU A CD2 1 
ATOM 4440 N N   . GLY B 2 537 ? 161.509 142.048 130.869 1.00 105.60 ? 537 GLY A N   1 
ATOM 4441 C CA  . GLY B 2 537 ? 161.725 141.050 129.841 1.00 106.98 ? 537 GLY A CA  1 
ATOM 4442 C C   . GLY B 2 537 ? 162.952 141.288 128.989 1.00 107.59 ? 537 GLY A C   1 
ATOM 4443 O O   . GLY B 2 537 ? 164.069 141.382 129.505 1.00 105.83 ? 537 GLY A O   1 
ATOM 4444 N N   . SER B 2 538 ? 162.753 141.346 127.675 1.00 122.03 ? 538 SER A N   1 
ATOM 4445 C CA  . SER B 2 538 ? 163.871 141.533 126.722 1.00 123.32 ? 538 SER A CA  1 
ATOM 4446 C C   . SER B 2 538 ? 164.515 142.886 126.966 1.00 123.93 ? 538 SER A C   1 
ATOM 4447 O O   . SER B 2 538 ? 163.842 143.740 127.525 1.00 128.21 ? 538 SER A O   1 
ATOM 4448 C CB  . SER B 2 538 ? 163.381 141.417 125.319 1.00 123.69 ? 538 SER A CB  1 
ATOM 4449 O OG  . SER B 2 538 ? 164.421 141.655 124.382 1.00 124.81 ? 538 SER A OG  1 
ATOM 4450 N N   . TRP B 2 539 ? 165.760 143.064 126.558 1.00 125.26 ? 539 TRP A N   1 
ATOM 4451 C CA  . TRP B 2 539 ? 166.479 144.317 126.756 1.00 125.33 ? 539 TRP A CA  1 
ATOM 4452 C C   . TRP B 2 539 ? 165.888 145.527 126.043 1.00 128.18 ? 539 TRP A C   1 
ATOM 4453 O O   . TRP B 2 539 ? 165.872 146.634 126.594 1.00 132.08 ? 539 TRP A O   1 
ATOM 4454 C CB  . TRP B 2 539 ? 167.920 144.079 126.305 1.00 124.64 ? 539 TRP A CB  1 
ATOM 4455 C CG  . TRP B 2 539 ? 168.861 143.736 127.425 1.00 133.18 ? 539 TRP A CG  1 
ATOM 4456 C CD1 . TRP B 2 539 ? 169.562 142.574 127.572 1.00 135.28 ? 539 TRP A CD1 1 
ATOM 4457 C CD2 . TRP B 2 539 ? 169.199 144.552 128.553 1.00 134.11 ? 539 TRP A CD2 1 
ATOM 4458 N NE1 . TRP B 2 539 ? 170.317 142.618 128.718 1.00 133.79 ? 539 TRP A NE1 1 
ATOM 4459 C CE2 . TRP B 2 539 ? 170.112 143.821 129.339 1.00 134.48 ? 539 TRP A CE2 1 
ATOM 4460 C CE3 . TRP B 2 539 ? 168.820 145.829 128.975 1.00 129.28 ? 539 TRP A CE3 1 
ATOM 4461 C CZ2 . TRP B 2 539 ? 170.650 144.325 130.520 1.00 130.08 ? 539 TRP A CZ2 1 
ATOM 4462 C CZ3 . TRP B 2 539 ? 169.356 146.327 130.147 1.00 130.94 ? 539 TRP A CZ3 1 
ATOM 4463 C CH2 . TRP B 2 539 ? 170.261 145.577 130.906 1.00 131.26 ? 539 TRP A CH2 1 
ATOM 4464 N N   . MET B 2 540 ? 165.389 145.333 124.820 1.00 124.65 ? 540 MET A N   1 
ATOM 4465 C CA  . MET B 2 540 ? 164.822 146.447 124.067 1.00 127.92 ? 540 MET A CA  1 
ATOM 4466 C C   . MET B 2 540 ? 163.624 147.048 124.789 1.00 124.25 ? 540 MET A C   1 
ATOM 4467 O O   . MET B 2 540 ? 163.482 148.276 124.858 1.00 124.60 ? 540 MET A O   1 
ATOM 4468 C CB  . MET B 2 540 ? 164.424 145.982 122.666 1.00 125.68 ? 540 MET A CB  1 
ATOM 4469 C CG  . MET B 2 540 ? 165.597 145.669 121.748 1.00 127.82 ? 540 MET A CG  1 
ATOM 4470 S SD  . MET B 2 540 ? 167.089 146.597 122.154 1.00 138.89 ? 540 MET A SD  1 
ATOM 4471 C CE  . MET B 2 540 ? 168.319 145.295 122.124 1.00 120.27 ? 540 MET A CE  1 
ATOM 4472 N N   . ILE B 2 541 ? 162.790 146.190 125.403 1.00 103.41 ? 541 ILE A N   1 
ATOM 4473 C CA  . ILE B 2 541 ? 161.545 146.648 126.090 1.00 103.55 ? 541 ILE A CA  1 
ATOM 4474 C C   . ILE B 2 541 ? 161.948 147.346 127.380 1.00 103.17 ? 541 ILE A C   1 
ATOM 4475 O O   . ILE B 2 541 ? 161.224 148.203 127.790 1.00 114.24 ? 541 ILE A O   1 
ATOM 4476 C CB  . ILE B 2 541 ? 160.576 145.501 126.379 1.00 103.90 ? 541 ILE A CB  1 
ATOM 4477 C CG1 . ILE B 2 541 ? 160.048 144.885 125.103 1.00 108.32 ? 541 ILE A CG1 1 
ATOM 4478 C CG2 . ILE B 2 541 ? 159.427 145.951 127.279 1.00 100.41 ? 541 ILE A CG2 1 
ATOM 4479 C CD1 . ILE B 2 541 ? 159.621 143.441 125.266 1.00 110.59 ? 541 ILE A CD1 1 
ATOM 4480 N N   . ARG B 2 542 ? 163.033 146.964 128.010 1.00 96.14  ? 542 ARG A N   1 
ATOM 4481 C CA  . ARG B 2 542 ? 163.526 147.660 129.193 1.00 97.49  ? 542 ARG A CA  1 
ATOM 4482 C C   . ARG B 2 542 ? 164.069 149.038 128.831 1.00 103.25 ? 542 ARG A C   1 
ATOM 4483 O O   . ARG B 2 542 ? 163.759 150.036 129.495 1.00 106.61 ? 542 ARG A O   1 
ATOM 4484 C CB  . ARG B 2 542 ? 164.596 146.807 129.872 1.00 101.13 ? 542 ARG A CB  1 
ATOM 4485 C CG  . ARG B 2 542 ? 165.297 147.462 131.041 1.00 103.65 ? 542 ARG A CG  1 
ATOM 4486 C CD  . ARG B 2 542 ? 166.164 146.450 131.778 1.00 104.40 ? 542 ARG A CD  1 
ATOM 4487 N NE  . ARG B 2 542 ? 165.387 145.320 132.273 1.00 106.02 ? 542 ARG A NE  1 
ATOM 4488 C CZ  . ARG B 2 542 ? 165.360 144.120 131.709 1.00 104.63 ? 542 ARG A CZ  1 
ATOM 4489 N NH1 . ARG B 2 542 ? 166.061 143.853 130.620 1.00 103.83 ? 542 ARG A NH1 1 
ATOM 4490 N NH2 . ARG B 2 542 ? 164.608 143.165 132.248 1.00 101.42 ? 542 ARG A NH2 1 
ATOM 4491 N N   . LEU B 2 543 ? 164.867 149.115 127.762 1.00 107.51 ? 543 LEU A N   1 
ATOM 4492 C CA  . LEU B 2 543 ? 165.413 150.404 127.344 1.00 106.11 ? 543 LEU A CA  1 
ATOM 4493 C C   . LEU B 2 543 ? 164.316 151.375 126.930 1.00 107.68 ? 543 LEU A C   1 
ATOM 4494 O O   . LEU B 2 543 ? 164.353 152.554 127.303 1.00 112.42 ? 543 LEU A O   1 
ATOM 4495 C CB  . LEU B 2 543 ? 166.419 150.225 126.207 1.00 103.80 ? 543 LEU A CB  1 
ATOM 4496 C CG  . LEU B 2 543 ? 167.887 150.015 126.589 1.00 109.38 ? 543 LEU A CG  1 
ATOM 4497 C CD1 . LEU B 2 543 ? 168.318 151.074 127.592 1.00 109.55 ? 543 LEU A CD1 1 
ATOM 4498 C CD2 . LEU B 2 543 ? 168.141 148.634 127.141 1.00 111.56 ? 543 LEU A CD2 1 
ATOM 4499 N N   . THR B 2 544 ? 163.334 150.912 126.151 1.00 99.01  ? 544 THR A N   1 
ATOM 4500 C CA  . THR B 2 544 ? 162.308 151.847 125.703 1.00 101.09 ? 544 THR A CA  1 
ATOM 4501 C C   . THR B 2 544 ? 161.420 152.296 126.857 1.00 98.60  ? 544 THR A C   1 
ATOM 4502 O O   . THR B 2 544 ? 160.994 153.454 126.885 1.00 106.21 ? 544 THR A O   1 
ATOM 4503 C CB  . THR B 2 544 ? 161.466 151.253 124.573 1.00 101.24 ? 544 THR A CB  1 
ATOM 4504 O OG1 . THR B 2 544 ? 160.419 152.169 124.230 1.00 108.20 ? 544 THR A OG1 1 
ATOM 4505 C CG2 . THR B 2 544 ? 160.844 149.952 124.984 1.00 100.53 ? 544 THR A CG2 1 
ATOM 4506 N N   . VAL B 2 545 ? 161.144 151.416 127.823 1.00 87.45  ? 545 VAL A N   1 
ATOM 4507 C CA  . VAL B 2 545 ? 160.373 151.833 128.989 1.00 83.21  ? 545 VAL A CA  1 
ATOM 4508 C C   . VAL B 2 545 ? 161.152 152.856 129.807 1.00 84.67  ? 545 VAL A C   1 
ATOM 4509 O O   . VAL B 2 545 ? 160.588 153.849 130.283 1.00 94.13  ? 545 VAL A O   1 
ATOM 4510 C CB  . VAL B 2 545 ? 159.974 150.609 129.832 1.00 83.45  ? 545 VAL A CB  1 
ATOM 4511 C CG1 . VAL B 2 545 ? 159.463 151.041 131.190 1.00 79.68  ? 545 VAL A CG1 1 
ATOM 4512 C CG2 . VAL B 2 545 ? 158.916 149.798 129.111 1.00 87.71  ? 545 VAL A CG2 1 
ATOM 4513 N N   . TRP B 2 546 ? 162.460 152.640 129.976 1.00 94.76  ? 546 TRP A N   1 
ATOM 4514 C CA  . TRP B 2 546 ? 163.279 153.614 130.693 1.00 100.18 ? 546 TRP A CA  1 
ATOM 4515 C C   . TRP B 2 546 ? 163.269 154.965 129.990 1.00 104.07 ? 546 TRP A C   1 
ATOM 4516 O O   . TRP B 2 546 ? 163.123 156.013 130.633 1.00 104.21 ? 546 TRP A O   1 
ATOM 4517 C CB  . TRP B 2 546 ? 164.709 153.094 130.825 1.00 98.78  ? 546 TRP A CB  1 
ATOM 4518 C CG  . TRP B 2 546 ? 164.975 152.384 132.106 1.00 95.48  ? 546 TRP A CG  1 
ATOM 4519 C CD1 . TRP B 2 546 ? 164.986 151.037 132.308 1.00 98.44  ? 546 TRP A CD1 1 
ATOM 4520 C CD2 . TRP B 2 546 ? 165.283 152.982 133.368 1.00 97.49  ? 546 TRP A CD2 1 
ATOM 4521 N NE1 . TRP B 2 546 ? 165.275 150.758 133.620 1.00 100.23 ? 546 TRP A NE1 1 
ATOM 4522 C CE2 . TRP B 2 546 ? 165.462 151.937 134.292 1.00 101.78 ? 546 TRP A CE2 1 
ATOM 4523 C CE3 . TRP B 2 546 ? 165.421 154.301 133.806 1.00 100.01 ? 546 TRP A CE3 1 
ATOM 4524 C CZ2 . TRP B 2 546 ? 165.772 152.168 135.628 1.00 103.13 ? 546 TRP A CZ2 1 
ATOM 4525 C CZ3 . TRP B 2 546 ? 165.729 154.529 135.133 1.00 99.87  ? 546 TRP A CZ3 1 
ATOM 4526 C CH2 . TRP B 2 546 ? 165.901 153.469 136.028 1.00 101.22 ? 546 TRP A CH2 1 
ATOM 4527 N N   . PHE B 2 547 ? 163.422 154.955 128.664 1.00 107.40 ? 547 PHE A N   1 
ATOM 4528 C CA  . PHE B 2 547 ? 163.410 156.198 127.902 1.00 105.84 ? 547 PHE A CA  1 
ATOM 4529 C C   . PHE B 2 547 ? 162.066 156.904 128.022 1.00 104.35 ? 547 PHE A C   1 
ATOM 4530 O O   . PHE B 2 547 ? 162.013 158.128 128.204 1.00 105.69 ? 547 PHE A O   1 
ATOM 4531 C CB  . PHE B 2 547 ? 163.747 155.903 126.439 1.00 104.96 ? 547 PHE A CB  1 
ATOM 4532 C CG  . PHE B 2 547 ? 163.193 156.904 125.468 1.00 112.09 ? 547 PHE A CG  1 
ATOM 4533 C CD1 . PHE B 2 547 ? 163.857 158.093 125.225 1.00 113.35 ? 547 PHE A CD1 1 
ATOM 4534 C CD2 . PHE B 2 547 ? 162.020 156.644 124.779 1.00 111.04 ? 547 PHE A CD2 1 
ATOM 4535 C CE1 . PHE B 2 547 ? 163.352 159.012 124.325 1.00 111.38 ? 547 PHE A CE1 1 
ATOM 4536 C CE2 . PHE B 2 547 ? 161.510 157.559 123.880 1.00 112.75 ? 547 PHE A CE2 1 
ATOM 4537 C CZ  . PHE B 2 547 ? 162.178 158.743 123.653 1.00 113.19 ? 547 PHE A CZ  1 
ATOM 4538 N N   . ILE B 2 548 ? 160.971 156.145 127.928 1.00 93.49  ? 548 ILE A N   1 
ATOM 4539 C CA  . ILE B 2 548 ? 159.636 156.722 128.053 1.00 91.33  ? 548 ILE A CA  1 
ATOM 4540 C C   . ILE B 2 548 ? 159.476 157.385 129.412 1.00 90.89  ? 548 ILE A C   1 
ATOM 4541 O O   . ILE B 2 548 ? 159.008 158.524 129.516 1.00 103.38 ? 548 ILE A O   1 
ATOM 4542 C CB  . ILE B 2 548 ? 158.563 155.642 127.828 1.00 88.02  ? 548 ILE A CB  1 
ATOM 4543 C CG1 . ILE B 2 548 ? 158.332 155.414 126.336 1.00 91.00  ? 548 ILE A CG1 1 
ATOM 4544 C CG2 . ILE B 2 548 ? 157.262 156.024 128.514 1.00 86.26  ? 548 ILE A CG2 1 
ATOM 4545 C CD1 . ILE B 2 548 ? 157.325 154.326 126.044 1.00 92.85  ? 548 ILE A CD1 1 
ATOM 4546 N N   . PHE B 2 549 ? 159.874 156.683 130.474 1.00 86.88  ? 549 PHE A N   1 
ATOM 4547 C CA  . PHE B 2 549 ? 159.756 157.244 131.814 1.00 86.80  ? 549 PHE A CA  1 
ATOM 4548 C C   . PHE B 2 549 ? 160.554 158.534 131.939 1.00 91.34  ? 549 PHE A C   1 
ATOM 4549 O O   . PHE B 2 549 ? 160.047 159.543 132.446 1.00 101.19 ? 549 PHE A O   1 
ATOM 4550 C CB  . PHE B 2 549 ? 160.224 156.223 132.850 1.00 89.31  ? 549 PHE A CB  1 
ATOM 4551 C CG  . PHE B 2 549 ? 160.839 156.839 134.073 1.00 85.22  ? 549 PHE A CG  1 
ATOM 4552 C CD1 . PHE B 2 549 ? 160.079 157.600 134.944 1.00 87.99  ? 549 PHE A CD1 1 
ATOM 4553 C CD2 . PHE B 2 549 ? 162.180 156.655 134.350 1.00 89.43  ? 549 PHE A CD2 1 
ATOM 4554 C CE1 . PHE B 2 549 ? 160.648 158.165 136.066 1.00 85.12  ? 549 PHE A CE1 1 
ATOM 4555 C CE2 . PHE B 2 549 ? 162.753 157.217 135.470 1.00 94.09  ? 549 PHE A CE2 1 
ATOM 4556 C CZ  . PHE B 2 549 ? 161.986 157.972 136.328 1.00 90.22  ? 549 PHE A CZ  1 
ATOM 4557 N N   . LEU B 2 550 ? 161.803 158.523 131.472 1.00 99.88  ? 550 LEU A N   1 
ATOM 4558 C CA  . LEU B 2 550 ? 162.652 159.699 131.630 1.00 106.55 ? 550 LEU A CA  1 
ATOM 4559 C C   . LEU B 2 550 ? 162.075 160.898 130.888 1.00 109.66 ? 550 LEU A C   1 
ATOM 4560 O O   . LEU B 2 550 ? 161.938 161.991 131.458 1.00 111.25 ? 550 LEU A O   1 
ATOM 4561 C CB  . LEU B 2 550 ? 164.068 159.391 131.144 1.00 102.16 ? 550 LEU A CB  1 
ATOM 4562 C CG  . LEU B 2 550 ? 164.925 158.550 132.090 1.00 100.82 ? 550 LEU A CG  1 
ATOM 4563 C CD1 . LEU B 2 550 ? 166.216 158.134 131.410 1.00 102.61 ? 550 LEU A CD1 1 
ATOM 4564 C CD2 . LEU B 2 550 ? 165.213 159.314 133.371 1.00 102.79 ? 550 LEU A CD2 1 
ATOM 4565 N N   . VAL B 2 551 ? 161.717 160.709 129.614 1.00 104.00 ? 551 VAL A N   1 
ATOM 4566 C CA  . VAL B 2 551 ? 161.232 161.839 128.830 1.00 101.17 ? 551 VAL A CA  1 
ATOM 4567 C C   . VAL B 2 551 ? 159.900 162.336 129.377 1.00 101.03 ? 551 VAL A C   1 
ATOM 4568 O O   . VAL B 2 551 ? 159.678 163.548 129.482 1.00 106.39 ? 551 VAL A O   1 
ATOM 4569 C CB  . VAL B 2 551 ? 161.143 161.481 127.334 1.00 100.81 ? 551 VAL A CB  1 
ATOM 4570 C CG1 . VAL B 2 551 ? 160.190 160.332 127.095 1.00 101.78 ? 551 VAL A CG1 1 
ATOM 4571 C CG2 . VAL B 2 551 ? 160.722 162.697 126.526 1.00 100.91 ? 551 VAL A CG2 1 
ATOM 4572 N N   . ALA B 2 552 ? 159.003 161.422 129.759 1.00 96.56  ? 552 ALA A N   1 
ATOM 4573 C CA  . ALA B 2 552 ? 157.716 161.837 130.300 1.00 92.47  ? 552 ALA A CA  1 
ATOM 4574 C C   . ALA B 2 552 ? 157.900 162.658 131.567 1.00 94.49  ? 552 ALA A C   1 
ATOM 4575 O O   . ALA B 2 552 ? 157.354 163.760 131.687 1.00 112.74 ? 552 ALA A O   1 
ATOM 4576 C CB  . ALA B 2 552 ? 156.839 160.616 130.573 1.00 91.79  ? 552 ALA A CB  1 
ATOM 4577 N N   . LEU B 2 553 ? 158.693 162.149 132.512 1.00 89.00  ? 553 LEU A N   1 
ATOM 4578 C CA  . LEU B 2 553 ? 158.912 162.871 133.760 1.00 93.86  ? 553 LEU A CA  1 
ATOM 4579 C C   . LEU B 2 553 ? 159.485 164.258 133.500 1.00 100.54 ? 553 LEU A C   1 
ATOM 4580 O O   . LEU B 2 553 ? 158.934 165.267 133.961 1.00 107.57 ? 553 LEU A O   1 
ATOM 4581 C CB  . LEU B 2 553 ? 159.842 162.067 134.667 1.00 97.56  ? 553 LEU A CB  1 
ATOM 4582 C CG  . LEU B 2 553 ? 160.369 162.778 135.913 1.00 99.02  ? 553 LEU A CG  1 
ATOM 4583 C CD1 . LEU B 2 553 ? 159.287 162.873 136.970 1.00 98.12  ? 553 LEU A CD1 1 
ATOM 4584 C CD2 . LEU B 2 553 ? 161.594 162.063 136.458 1.00 98.73  ? 553 LEU A CD2 1 
ATOM 4585 N N   . PHE B 2 554 ? 160.577 164.332 132.734 1.00 114.63 ? 554 PHE A N   1 
ATOM 4586 C CA  . PHE B 2 554 ? 161.261 165.611 132.567 1.00 116.57 ? 554 PHE A CA  1 
ATOM 4587 C C   . PHE B 2 554 ? 160.401 166.612 131.804 1.00 112.09 ? 554 PHE A C   1 
ATOM 4588 O O   . PHE B 2 554 ? 160.290 167.779 132.201 1.00 114.18 ? 554 PHE A O   1 
ATOM 4589 C CB  . PHE B 2 554 ? 162.604 165.397 131.873 1.00 118.48 ? 554 PHE A CB  1 
ATOM 4590 C CG  . PHE B 2 554 ? 163.689 164.933 132.801 1.00 123.01 ? 554 PHE A CG  1 
ATOM 4591 C CD1 . PHE B 2 554 ? 163.717 165.362 134.117 1.00 119.38 ? 554 PHE A CD1 1 
ATOM 4592 C CD2 . PHE B 2 554 ? 164.671 164.062 132.365 1.00 122.73 ? 554 PHE A CD2 1 
ATOM 4593 C CE1 . PHE B 2 554 ? 164.708 164.937 134.979 1.00 117.38 ? 554 PHE A CE1 1 
ATOM 4594 C CE2 . PHE B 2 554 ? 165.665 163.633 133.223 1.00 122.01 ? 554 PHE A CE2 1 
ATOM 4595 C CZ  . PHE B 2 554 ? 165.683 164.072 134.532 1.00 121.21 ? 554 PHE A CZ  1 
ATOM 4596 N N   . PHE B 2 555 ? 159.770 166.177 130.710 1.00 96.75  ? 555 PHE A N   1 
ATOM 4597 C CA  . PHE B 2 555 ? 158.998 167.115 129.909 1.00 96.27  ? 555 PHE A CA  1 
ATOM 4598 C C   . PHE B 2 555 ? 157.721 167.546 130.615 1.00 99.18  ? 555 PHE A C   1 
ATOM 4599 O O   . PHE B 2 555 ? 157.321 168.708 130.497 1.00 109.95 ? 555 PHE A O   1 
ATOM 4600 C CB  . PHE B 2 555 ? 158.689 166.510 128.543 1.00 98.27  ? 555 PHE A CB  1 
ATOM 4601 C CG  . PHE B 2 555 ? 159.770 166.741 127.529 1.00 104.75 ? 555 PHE A CG  1 
ATOM 4602 C CD1 . PHE B 2 555 ? 161.078 166.950 127.931 1.00 105.39 ? 555 PHE A CD1 1 
ATOM 4603 C CD2 . PHE B 2 555 ? 159.481 166.764 126.177 1.00 106.63 ? 555 PHE A CD2 1 
ATOM 4604 C CE1 . PHE B 2 555 ? 162.077 167.165 127.006 1.00 107.69 ? 555 PHE A CE1 1 
ATOM 4605 C CE2 . PHE B 2 555 ? 160.478 166.981 125.246 1.00 110.30 ? 555 PHE A CE2 1 
ATOM 4606 C CZ  . PHE B 2 555 ? 161.777 167.181 125.662 1.00 110.55 ? 555 PHE A CZ  1 
ATOM 4607 N N   . ASN B 2 556 ? 157.068 166.644 131.353 1.00 93.93  ? 556 ASN A N   1 
ATOM 4608 C CA  . ASN B 2 556 ? 155.909 167.052 132.136 1.00 89.20  ? 556 ASN A CA  1 
ATOM 4609 C C   . ASN B 2 556 ? 156.304 168.057 133.208 1.00 95.14  ? 556 ASN A C   1 
ATOM 4610 O O   . ASN B 2 556 ? 155.595 169.047 133.431 1.00 104.08 ? 556 ASN A O   1 
ATOM 4611 C CB  . ASN B 2 556 ? 155.246 165.828 132.760 1.00 89.17  ? 556 ASN A CB  1 
ATOM 4612 C CG  . ASN B 2 556 ? 154.548 164.967 131.735 1.00 92.78  ? 556 ASN A CG  1 
ATOM 4613 O OD1 . ASN B 2 556 ? 153.950 165.473 130.788 1.00 97.50  ? 556 ASN A OD1 1 
ATOM 4614 N ND2 . ASN B 2 556 ? 154.635 163.655 131.908 1.00 93.27  ? 556 ASN A ND2 1 
ATOM 4615 N N   . LEU B 2 557 ? 157.439 167.828 133.876 1.00 107.87 ? 557 LEU A N   1 
ATOM 4616 C CA  . LEU B 2 557 ? 157.901 168.785 134.873 1.00 108.29 ? 557 LEU A CA  1 
ATOM 4617 C C   . LEU B 2 557 ? 158.157 170.149 134.246 1.00 108.68 ? 557 LEU A C   1 
ATOM 4618 O O   . LEU B 2 557 ? 157.748 171.181 134.794 1.00 109.25 ? 557 LEU A O   1 
ATOM 4619 C CB  . LEU B 2 557 ? 159.164 168.259 135.555 1.00 109.45 ? 557 LEU A CB  1 
ATOM 4620 C CG  . LEU B 2 557 ? 159.063 168.020 137.061 1.00 111.83 ? 557 LEU A CG  1 
ATOM 4621 C CD1 . LEU B 2 557 ? 160.420 167.652 137.637 1.00 111.11 ? 557 LEU A CD1 1 
ATOM 4622 C CD2 . LEU B 2 557 ? 158.494 169.243 137.761 1.00 109.51 ? 557 LEU A CD2 1 
ATOM 4623 N N   . LEU B 2 558 ? 158.803 170.136 133.070 1.00 106.19 ? 558 LEU A N   1 
ATOM 4624 C CA  . LEU B 2 558 ? 159.159 171.376 132.337 1.00 104.81 ? 558 LEU A CA  1 
ATOM 4625 C C   . LEU B 2 558 ? 157.888 172.111 131.925 1.00 104.05 ? 558 LEU A C   1 
ATOM 4626 O O   . LEU B 2 558 ? 157.926 173.331 131.969 1.00 109.01 ? 558 LEU A O   1 
ATOM 4627 C CB  . LEU B 2 558 ? 159.983 171.008 131.104 1.00 106.20 ? 558 LEU A CB  1 
ATOM 4628 C CG  . LEU B 2 558 ? 160.011 172.031 129.962 1.00 106.62 ? 558 LEU A CG  1 
ATOM 4629 C CD1 . LEU B 2 558 ? 161.281 171.868 129.157 1.00 109.14 ? 558 LEU A CD1 1 
ATOM 4630 C CD2 . LEU B 2 558 ? 158.813 171.925 129.035 1.00 106.55 ? 558 LEU A CD2 1 
ATOM 4631 N N   . VAL B 2 559 ? 156.870 171.403 131.432 1.00 100.83 ? 559 VAL A N   1 
ATOM 4632 C CA  . VAL B 2 559 ? 155.626 172.018 130.981 1.00 98.29  ? 559 VAL A CA  1 
ATOM 4633 C C   . VAL B 2 559 ? 154.872 172.608 132.163 1.00 100.05 ? 559 VAL A C   1 
ATOM 4634 O O   . VAL B 2 559 ? 154.349 173.727 132.089 1.00 104.44 ? 559 VAL A O   1 
ATOM 4635 C CB  . VAL B 2 559 ? 154.769 170.998 130.209 1.00 91.99  ? 559 VAL A CB  1 
ATOM 4636 C CG1 . VAL B 2 559 ? 153.316 171.433 130.184 1.00 87.97  ? 559 VAL A CG1 1 
ATOM 4637 C CG2 . VAL B 2 559 ? 155.296 170.830 128.797 1.00 96.95  ? 559 VAL A CG2 1 
ATOM 4638 N N   . ILE B 2 560 ? 154.817 171.874 133.277 1.00 105.33 ? 560 ILE A N   1 
ATOM 4639 C CA  . ILE B 2 560 ? 154.146 172.382 134.470 1.00 102.26 ? 560 ILE A CA  1 
ATOM 4640 C C   . ILE B 2 560 ? 154.827 173.653 134.957 1.00 106.13 ? 560 ILE A C   1 
ATOM 4641 O O   . ILE B 2 560 ? 154.167 174.655 135.263 1.00 108.70 ? 560 ILE A O   1 
ATOM 4642 C CB  . ILE B 2 560 ? 154.119 171.303 135.566 1.00 105.48 ? 560 ILE A CB  1 
ATOM 4643 C CG1 . ILE B 2 560 ? 153.107 170.214 135.217 1.00 105.67 ? 560 ILE A CG1 1 
ATOM 4644 C CG2 . ILE B 2 560 ? 153.784 171.920 136.912 1.00 107.10 ? 560 ILE A CG2 1 
ATOM 4645 C CD1 . ILE B 2 560 ? 153.287 168.949 136.017 1.00 107.96 ? 560 ILE A CD1 1 
ATOM 4646 N N   . LEU B 2 561 ? 156.161 173.637 135.023 1.00 119.69 ? 561 LEU A N   1 
ATOM 4647 C CA  . LEU B 2 561 ? 156.889 174.800 135.519 1.00 121.70 ? 561 LEU A CA  1 
ATOM 4648 C C   . LEU B 2 561 ? 156.670 176.015 134.628 1.00 120.84 ? 561 LEU A C   1 
ATOM 4649 O O   . LEU B 2 561 ? 156.471 177.130 135.123 1.00 120.58 ? 561 LEU A O   1 
ATOM 4650 C CB  . LEU B 2 561 ? 158.379 174.478 135.629 1.00 120.33 ? 561 LEU A CB  1 
ATOM 4651 C CG  . LEU B 2 561 ? 158.836 173.810 136.927 1.00 121.29 ? 561 LEU A CG  1 
ATOM 4652 C CD1 . LEU B 2 561 ? 160.341 173.939 137.092 1.00 119.72 ? 561 LEU A CD1 1 
ATOM 4653 C CD2 . LEU B 2 561 ? 158.110 174.398 138.126 1.00 118.17 ? 561 LEU A CD2 1 
ATOM 4654 N N   . THR B 2 562 ? 156.703 175.822 133.309 1.00 124.20 ? 562 THR A N   1 
ATOM 4655 C CA  . THR B 2 562 ? 156.525 176.947 132.397 1.00 122.96 ? 562 THR A CA  1 
ATOM 4656 C C   . THR B 2 562 ? 155.101 177.487 132.450 1.00 123.23 ? 562 THR A C   1 
ATOM 4657 O O   . THR B 2 562 ? 154.895 178.705 132.452 1.00 125.61 ? 562 THR A O   1 
ATOM 4658 C CB  . THR B 2 562 ? 156.883 176.533 130.972 1.00 124.28 ? 562 THR A CB  1 
ATOM 4659 O OG1 . THR B 2 562 ? 156.328 175.241 130.695 1.00 126.23 ? 562 THR A OG1 1 
ATOM 4660 C CG2 . THR B 2 562 ? 158.390 176.473 130.802 1.00 127.56 ? 562 THR A CG2 1 
ATOM 4661 N N   . THR B 2 563 ? 154.107 176.599 132.491 1.00 117.37 ? 563 THR A N   1 
ATOM 4662 C CA  . THR B 2 563 ? 152.718 177.041 132.431 1.00 115.45 ? 563 THR A CA  1 
ATOM 4663 C C   . THR B 2 563 ? 152.281 177.699 133.734 1.00 117.03 ? 563 THR A C   1 
ATOM 4664 O O   . THR B 2 563 ? 151.653 178.764 133.721 1.00 121.49 ? 563 THR A O   1 
ATOM 4665 C CB  . THR B 2 563 ? 151.812 175.856 132.096 1.00 116.24 ? 563 THR A CB  1 
ATOM 4666 O OG1 . THR B 2 563 ? 152.016 175.470 130.731 1.00 114.71 ? 563 THR A OG1 1 
ATOM 4667 C CG2 . THR B 2 563 ? 150.355 176.217 132.308 1.00 117.15 ? 563 THR A CG2 1 
ATOM 4668 N N   . PHE B 2 564 ? 152.610 177.091 134.872 1.00 120.31 ? 564 PHE A N   1 
ATOM 4669 C CA  . PHE B 2 564 ? 152.022 177.531 136.131 1.00 121.74 ? 564 PHE A CA  1 
ATOM 4670 C C   . PHE B 2 564 ? 152.888 178.549 136.867 1.00 125.31 ? 564 PHE A C   1 
ATOM 4671 O O   . PHE B 2 564 ? 152.386 179.590 137.300 1.00 125.06 ? 564 PHE A O   1 
ATOM 4672 C CB  . PHE B 2 564 ? 151.751 176.320 137.028 1.00 122.19 ? 564 PHE A CB  1 
ATOM 4673 C CG  . PHE B 2 564 ? 150.504 175.568 136.663 1.00 121.05 ? 564 PHE A CG  1 
ATOM 4674 C CD1 . PHE B 2 564 ? 149.526 176.162 135.883 1.00 121.36 ? 564 PHE A CD1 1 
ATOM 4675 C CD2 . PHE B 2 564 ? 150.310 174.269 137.095 1.00 123.55 ? 564 PHE A CD2 1 
ATOM 4676 C CE1 . PHE B 2 564 ? 148.379 175.473 135.543 1.00 123.06 ? 564 PHE A CE1 1 
ATOM 4677 C CE2 . PHE B 2 564 ? 149.164 173.575 136.759 1.00 121.68 ? 564 PHE A CE2 1 
ATOM 4678 C CZ  . PHE B 2 564 ? 148.198 174.179 135.982 1.00 119.88 ? 564 PHE A CZ  1 
ATOM 4679 N N   . ALA B 2 565 ? 154.183 178.262 137.027 1.00 144.60 ? 565 ALA A N   1 
ATOM 4680 C CA  . ALA B 2 565 ? 155.036 179.132 137.831 1.00 144.63 ? 565 ALA A CA  1 
ATOM 4681 C C   . ALA B 2 565 ? 155.151 180.525 137.223 1.00 146.10 ? 565 ALA A C   1 
ATOM 4682 O O   . ALA B 2 565 ? 155.056 181.531 137.937 1.00 145.59 ? 565 ALA A O   1 
ATOM 4683 C CB  . ALA B 2 565 ? 156.419 178.505 138.000 1.00 142.46 ? 565 ALA A CB  1 
ATOM 4684 N N   . SER B 2 566 ? 155.351 180.608 135.909 1.00 159.69 ? 566 SER A N   1 
ATOM 4685 C CA  . SER B 2 566 ? 155.522 181.891 135.228 1.00 160.36 ? 566 SER A CA  1 
ATOM 4686 C C   . SER B 2 566 ? 154.206 182.263 134.551 1.00 161.22 ? 566 SER A C   1 
ATOM 4687 O O   . SER B 2 566 ? 154.010 182.068 133.351 1.00 160.44 ? 566 SER A O   1 
ATOM 4688 C CB  . SER B 2 566 ? 156.673 181.819 134.230 1.00 159.54 ? 566 SER A CB  1 
ATOM 4689 O OG  . SER B 2 566 ? 156.265 181.187 133.029 1.00 159.87 ? 566 SER A OG  1 
ATOM 4690 N N   . CYS B 2 567 ? 153.292 182.815 135.346 1.00 164.32 ? 567 CYS A N   1 
ATOM 4691 C CA  . CYS B 2 567 ? 151.998 183.233 134.829 1.00 163.75 ? 567 CYS A CA  1 
ATOM 4692 C C   . CYS B 2 567 ? 151.363 184.218 135.798 1.00 163.69 ? 567 CYS A C   1 
ATOM 4693 O O   . CYS B 2 567 ? 151.675 184.225 136.992 1.00 162.13 ? 567 CYS A O   1 
ATOM 4694 C CB  . CYS B 2 567 ? 151.066 182.036 134.609 1.00 164.51 ? 567 CYS A CB  1 
ATOM 4695 S SG  . CYS B 2 567 ? 150.118 181.558 136.072 1.00 168.33 ? 567 CYS A SG  1 
ATOM 4696 N N   . THR B 2 568 ? 150.470 185.048 135.265 1.00 169.05 ? 568 THR A N   1 
ATOM 4697 C CA  . THR B 2 568 ? 149.652 185.947 136.065 1.00 170.81 ? 568 THR A CA  1 
ATOM 4698 C C   . THR B 2 568 ? 148.160 185.765 135.838 1.00 169.95 ? 568 THR A C   1 
ATOM 4699 O O   . THR B 2 568 ? 147.375 186.027 136.752 1.00 168.64 ? 568 THR A O   1 
ATOM 4700 C CB  . THR B 2 568 ? 150.024 187.413 135.786 1.00 170.57 ? 568 THR A CB  1 
ATOM 4701 O OG1 . THR B 2 568 ? 149.150 188.280 136.521 1.00 170.40 ? 568 THR A OG1 1 
ATOM 4702 C CG2 . THR B 2 568 ? 149.918 187.726 134.300 1.00 168.31 ? 568 THR A CG2 1 
ATOM 4703 N N   . SER B 2 569 ? 147.750 185.325 134.651 1.00 168.44 ? 569 SER A N   1 
ATOM 4704 C CA  . SER B 2 569 ? 146.361 185.010 134.356 1.00 168.64 ? 569 SER A CA  1 
ATOM 4705 C C   . SER B 2 569 ? 146.312 183.659 133.662 1.00 167.51 ? 569 SER A C   1 
ATOM 4706 O O   . SER B 2 569 ? 147.132 183.375 132.785 1.00 166.15 ? 569 SER A O   1 
ATOM 4707 C CB  . SER B 2 569 ? 145.711 186.084 133.476 1.00 167.01 ? 569 SER A CB  1 
ATOM 4708 O OG  . SER B 2 569 ? 145.817 185.749 132.103 1.00 166.58 ? 569 SER A OG  1 
ATOM 4709 N N   . LEU B 2 570 ? 145.348 182.830 134.055 1.00 147.42 ? 570 LEU A N   1 
ATOM 4710 C CA  . LEU B 2 570 ? 145.261 181.466 133.545 1.00 146.60 ? 570 LEU A CA  1 
ATOM 4711 C C   . LEU B 2 570 ? 144.006 181.292 132.703 1.00 146.17 ? 570 LEU A C   1 
ATOM 4712 O O   . LEU B 2 570 ? 142.906 181.129 133.253 1.00 144.17 ? 570 LEU A O   1 
ATOM 4713 C CB  . LEU B 2 570 ? 145.272 180.460 134.700 1.00 145.89 ? 570 LEU A CB  1 
ATOM 4714 C CG  . LEU B 2 570 ? 146.642 179.976 135.179 1.00 145.89 ? 570 LEU A CG  1 
ATOM 4715 C CD1 . LEU B 2 570 ? 146.526 178.611 135.835 1.00 145.26 ? 570 LEU A CD1 1 
ATOM 4716 C CD2 . LEU B 2 570 ? 147.633 179.933 134.029 1.00 144.43 ? 570 LEU A CD2 1 
ATOM 4717 N N   . PRO B 2 571 ? 144.110 181.320 131.378 1.00 135.18 ? 571 PRO A N   1 
ATOM 4718 C CA  . PRO B 2 571 ? 142.963 180.958 130.542 1.00 130.75 ? 571 PRO A CA  1 
ATOM 4719 C C   . PRO B 2 571 ? 142.604 179.492 130.720 1.00 128.87 ? 571 PRO A C   1 
ATOM 4720 O O   . PRO B 2 571 ? 143.396 178.680 131.203 1.00 132.81 ? 571 PRO A O   1 
ATOM 4721 C CB  . PRO B 2 571 ? 143.449 181.244 129.117 1.00 129.67 ? 571 PRO A CB  1 
ATOM 4722 C CG  . PRO B 2 571 ? 144.597 182.185 129.282 1.00 131.97 ? 571 PRO A CG  1 
ATOM 4723 C CD  . PRO B 2 571 ? 145.242 181.817 130.581 1.00 131.70 ? 571 PRO A CD  1 
ATOM 4724 N N   . SER B 2 572 ? 141.374 179.163 130.324 1.00 128.65 ? 572 SER A N   1 
ATOM 4725 C CA  . SER B 2 572 ? 140.875 177.804 130.510 1.00 134.01 ? 572 SER A CA  1 
ATOM 4726 C C   . SER B 2 572 ? 141.718 176.787 129.747 1.00 136.11 ? 572 SER A C   1 
ATOM 4727 O O   . SER B 2 572 ? 142.041 175.718 130.278 1.00 135.46 ? 572 SER A O   1 
ATOM 4728 C CB  . SER B 2 572 ? 139.415 177.728 130.073 1.00 133.00 ? 572 SER A CB  1 
ATOM 4729 O OG  . SER B 2 572 ? 139.266 178.213 128.751 1.00 138.07 ? 572 SER A OG  1 
ATOM 4730 N N   . SER B 2 573 ? 142.082 177.101 128.502 1.00 134.75 ? 573 SER A N   1 
ATOM 4731 C CA  . SER B 2 573 ? 142.865 176.164 127.701 1.00 137.60 ? 573 SER A CA  1 
ATOM 4732 C C   . SER B 2 573 ? 144.236 175.914 128.316 1.00 136.07 ? 573 SER A C   1 
ATOM 4733 O O   . SER B 2 573 ? 144.687 174.766 128.404 1.00 135.05 ? 573 SER A O   1 
ATOM 4734 C CB  . SER B 2 573 ? 143.008 176.692 126.276 1.00 135.86 ? 573 SER A CB  1 
ATOM 4735 O OG  . SER B 2 573 ? 143.770 177.887 126.255 1.00 133.67 ? 573 SER A OG  1 
ATOM 4736 N N   . LYS B 2 574 ? 144.917 176.980 128.740 1.00 123.20 ? 574 LYS A N   1 
ATOM 4737 C CA  . LYS B 2 574 ? 146.243 176.833 129.332 1.00 122.14 ? 574 LYS A CA  1 
ATOM 4738 C C   . LYS B 2 574 ? 146.185 176.032 130.628 1.00 122.52 ? 574 LYS A C   1 
ATOM 4739 O O   . LYS B 2 574 ? 147.031 175.160 130.871 1.00 126.63 ? 574 LYS A O   1 
ATOM 4740 C CB  . LYS B 2 574 ? 146.847 178.214 129.572 1.00 122.26 ? 574 LYS A CB  1 
ATOM 4741 C CG  . LYS B 2 574 ? 147.993 178.239 130.556 1.00 122.45 ? 574 LYS A CG  1 
ATOM 4742 C CD  . LYS B 2 574 ? 148.687 179.588 130.538 1.00 124.37 ? 574 LYS A CD  1 
ATOM 4743 C CE  . LYS B 2 574 ? 149.192 179.923 129.147 1.00 123.37 ? 574 LYS A CE  1 
ATOM 4744 N NZ  . LYS B 2 574 ? 150.222 180.995 129.173 1.00 123.05 ? 574 LYS A NZ  1 
ATOM 4745 N N   . LEU B 2 575 ? 145.188 176.314 131.469 1.00 117.89 ? 575 LEU A N   1 
ATOM 4746 C CA  . LEU B 2 575 ? 145.029 175.567 132.711 1.00 120.66 ? 575 LEU A CA  1 
ATOM 4747 C C   . LEU B 2 575 ? 144.746 174.096 132.433 1.00 119.76 ? 575 LEU A C   1 
ATOM 4748 O O   . LEU B 2 575 ? 145.288 173.210 133.106 1.00 128.01 ? 575 LEU A O   1 
ATOM 4749 C CB  . LEU B 2 575 ? 143.921 176.206 133.554 1.00 119.91 ? 575 LEU A CB  1 
ATOM 4750 C CG  . LEU B 2 575 ? 143.252 175.474 134.719 1.00 120.36 ? 575 LEU A CG  1 
ATOM 4751 C CD1 . LEU B 2 575 ? 142.732 176.502 135.703 1.00 124.51 ? 575 LEU A CD1 1 
ATOM 4752 C CD2 . LEU B 2 575 ? 142.097 174.601 134.244 1.00 116.50 ? 575 LEU A CD2 1 
ATOM 4753 N N   . PHE B 2 576 ? 143.907 173.816 131.435 1.00 98.70  ? 576 PHE A N   1 
ATOM 4754 C CA  . PHE B 2 576 ? 143.635 172.431 131.074 1.00 103.72 ? 576 PHE A CA  1 
ATOM 4755 C C   . PHE B 2 576 ? 144.899 171.732 130.591 1.00 108.97 ? 576 PHE A C   1 
ATOM 4756 O O   . PHE B 2 576 ? 145.143 170.569 130.932 1.00 114.30 ? 576 PHE A O   1 
ATOM 4757 C CB  . PHE B 2 576 ? 142.548 172.380 130.005 1.00 101.21 ? 576 PHE A CB  1 
ATOM 4758 C CG  . PHE B 2 576 ? 141.155 172.432 130.558 1.00 106.40 ? 576 PHE A CG  1 
ATOM 4759 C CD1 . PHE B 2 576 ? 140.928 172.314 131.917 1.00 110.08 ? 576 PHE A CD1 1 
ATOM 4760 C CD2 . PHE B 2 576 ? 140.073 172.603 129.716 1.00 107.52 ? 576 PHE A CD2 1 
ATOM 4761 C CE1 . PHE B 2 576 ? 139.645 172.363 132.424 1.00 112.14 ? 576 PHE A CE1 1 
ATOM 4762 C CE2 . PHE B 2 576 ? 138.789 172.648 130.216 1.00 110.88 ? 576 PHE A CE2 1 
ATOM 4763 C CZ  . PHE B 2 576 ? 138.574 172.529 131.572 1.00 112.52 ? 576 PHE A CZ  1 
ATOM 4764 N N   . ILE B 2 577 ? 145.713 172.429 129.796 1.00 103.72 ? 577 ILE A N   1 
ATOM 4765 C CA  . ILE B 2 577 ? 146.967 171.850 129.321 1.00 103.53 ? 577 ILE A CA  1 
ATOM 4766 C C   . ILE B 2 577 ? 147.869 171.509 130.499 1.00 101.46 ? 577 ILE A C   1 
ATOM 4767 O O   . ILE B 2 577 ? 148.464 170.424 130.556 1.00 103.19 ? 577 ILE A O   1 
ATOM 4768 C CB  . ILE B 2 577 ? 147.656 172.814 128.338 1.00 100.14 ? 577 ILE A CB  1 
ATOM 4769 C CG1 . ILE B 2 577 ? 146.990 172.739 126.966 1.00 103.28 ? 577 ILE A CG1 1 
ATOM 4770 C CG2 . ILE B 2 577 ? 149.134 172.497 128.224 1.00 95.44  ? 577 ILE A CG2 1 
ATOM 4771 C CD1 . ILE B 2 577 ? 147.196 171.423 126.266 1.00 102.56 ? 577 ILE A CD1 1 
ATOM 4772 N N   . GLY B 2 578 ? 147.974 172.425 131.462 1.00 95.20  ? 578 GLY A N   1 
ATOM 4773 C CA  . GLY B 2 578 ? 148.753 172.141 132.657 1.00 94.02  ? 578 GLY A CA  1 
ATOM 4774 C C   . GLY B 2 578 ? 148.229 170.943 133.429 1.00 98.37  ? 578 GLY A C   1 
ATOM 4775 O O   . GLY B 2 578 ? 149.004 170.158 133.981 1.00 105.73 ? 578 GLY A O   1 
ATOM 4776 N N   . LEU B 2 579 ? 146.906 170.785 133.479 1.00 99.56  ? 579 LEU A N   1 
ATOM 4777 C CA  . LEU B 2 579 ? 146.338 169.655 134.211 1.00 101.79 ? 579 LEU A CA  1 
ATOM 4778 C C   . LEU B 2 579 ? 146.634 168.336 133.500 1.00 102.01 ? 579 LEU A C   1 
ATOM 4779 O O   . LEU B 2 579 ? 146.948 167.327 134.152 1.00 106.92 ? 579 LEU A O   1 
ATOM 4780 C CB  . LEU B 2 579 ? 144.836 169.859 134.397 1.00 101.55 ? 579 LEU A CB  1 
ATOM 4781 C CG  . LEU B 2 579 ? 144.455 171.050 135.279 1.00 102.49 ? 579 LEU A CG  1 
ATOM 4782 C CD1 . LEU B 2 579 ? 143.053 170.887 135.821 1.00 100.23 ? 579 LEU A CD1 1 
ATOM 4783 C CD2 . LEU B 2 579 ? 145.446 171.224 136.418 1.00 102.40 ? 579 LEU A CD2 1 
ATOM 4784 N N   . ILE B 2 580 ? 146.535 168.313 132.167 1.00 82.88  ? 580 ILE A N   1 
ATOM 4785 C CA  . ILE B 2 580 ? 146.945 167.112 131.440 1.00 86.99  ? 580 ILE A CA  1 
ATOM 4786 C C   . ILE B 2 580 ? 148.422 166.831 131.679 1.00 94.45  ? 580 ILE A C   1 
ATOM 4787 O O   . ILE B 2 580 ? 148.837 165.671 131.787 1.00 95.68  ? 580 ILE A O   1 
ATOM 4788 C CB  . ILE B 2 580 ? 146.620 167.212 129.938 1.00 79.55  ? 580 ILE A CB  1 
ATOM 4789 C CG1 . ILE B 2 580 ? 145.117 167.250 129.698 1.00 85.28  ? 580 ILE A CG1 1 
ATOM 4790 C CG2 . ILE B 2 580 ? 147.239 166.048 129.184 1.00 86.68  ? 580 ILE A CG2 1 
ATOM 4791 C CD1 . ILE B 2 580 ? 144.741 167.609 128.284 1.00 96.24  ? 580 ILE A CD1 1 
ATOM 4792 N N   . SER B 2 581 ? 149.237 167.883 131.764 1.00 92.78  ? 581 SER A N   1 
ATOM 4793 C CA  . SER B 2 581 ? 150.645 167.689 132.093 1.00 87.04  ? 581 SER A CA  1 
ATOM 4794 C C   . SER B 2 581 ? 150.826 167.046 133.463 1.00 92.65  ? 581 SER A C   1 
ATOM 4795 O O   . SER B 2 581 ? 151.681 166.173 133.639 1.00 111.63 ? 581 SER A O   1 
ATOM 4796 C CB  . SER B 2 581 ? 151.372 169.029 132.029 1.00 92.35  ? 581 SER A CB  1 
ATOM 4797 O OG  . SER B 2 581 ? 152.757 168.867 132.276 1.00 100.25 ? 581 SER A OG  1 
ATOM 4798 N N   . VAL B 2 582 ? 150.028 167.467 134.445 1.00 77.38  ? 582 VAL A N   1 
ATOM 4799 C CA  . VAL B 2 582 ? 150.119 166.888 135.786 1.00 83.59  ? 582 VAL A CA  1 
ATOM 4800 C C   . VAL B 2 582 ? 149.767 165.403 135.752 1.00 89.88  ? 582 VAL A C   1 
ATOM 4801 O O   . VAL B 2 582 ? 150.457 164.561 136.348 1.00 94.51  ? 582 VAL A O   1 
ATOM 4802 C CB  . VAL B 2 582 ? 149.213 167.661 136.762 1.00 81.77  ? 582 VAL A CB  1 
ATOM 4803 C CG1 . VAL B 2 582 ? 148.766 166.768 137.906 1.00 91.11  ? 582 VAL A CG1 1 
ATOM 4804 C CG2 . VAL B 2 582 ? 149.928 168.889 137.293 1.00 85.86  ? 582 VAL A CG2 1 
ATOM 4805 N N   . SER B 2 583 ? 148.682 165.060 135.055 1.00 84.74  ? 583 SER A N   1 
ATOM 4806 C CA  . SER B 2 583 ? 148.281 163.657 134.973 1.00 87.34  ? 583 SER A CA  1 
ATOM 4807 C C   . SER B 2 583 ? 149.345 162.818 134.270 1.00 90.06  ? 583 SER A C   1 
ATOM 4808 O O   . SER B 2 583 ? 149.645 161.688 134.687 1.00 95.67  ? 583 SER A O   1 
ATOM 4809 C CB  . SER B 2 583 ? 146.940 163.536 134.255 1.00 92.36  ? 583 SER A CB  1 
ATOM 4810 O OG  . SER B 2 583 ? 146.815 162.271 133.633 1.00 104.21 ? 583 SER A OG  1 
ATOM 4811 N N   . ASN B 2 584 ? 149.930 163.357 133.200 1.00 85.24  ? 584 ASN A N   1 
ATOM 4812 C CA  . ASN B 2 584 ? 150.998 162.650 132.506 1.00 88.18  ? 584 ASN A CA  1 
ATOM 4813 C C   . ASN B 2 584 ? 152.217 162.481 133.402 1.00 92.58  ? 584 ASN A C   1 
ATOM 4814 O O   . ASN B 2 584 ? 152.913 161.463 133.331 1.00 100.83 ? 584 ASN A O   1 
ATOM 4815 C CB  . ASN B 2 584 ? 151.363 163.396 131.226 1.00 94.31  ? 584 ASN A CB  1 
ATOM 4816 C CG  . ASN B 2 584 ? 150.228 163.418 130.227 1.00 98.55  ? 584 ASN A CG  1 
ATOM 4817 O OD1 . ASN B 2 584 ? 149.402 162.506 130.191 1.00 96.28  ? 584 ASN A OD1 1 
ATOM 4818 N ND2 . ASN B 2 584 ? 150.177 164.462 129.410 1.00 97.65  ? 584 ASN A ND2 1 
ATOM 4819 N N   . LEU B 2 585 ? 152.494 163.471 134.252 1.00 88.01  ? 585 LEU A N   1 
ATOM 4820 C CA  . LEU B 2 585 ? 153.584 163.338 135.210 1.00 82.29  ? 585 LEU A CA  1 
ATOM 4821 C C   . LEU B 2 585 ? 153.318 162.197 136.182 1.00 88.13  ? 585 LEU A C   1 
ATOM 4822 O O   . LEU B 2 585 ? 154.233 161.443 136.534 1.00 95.90  ? 585 LEU A O   1 
ATOM 4823 C CB  . LEU B 2 585 ? 153.782 164.653 135.963 1.00 80.25  ? 585 LEU A CB  1 
ATOM 4824 C CG  . LEU B 2 585 ? 154.489 164.568 137.314 1.00 86.06  ? 585 LEU A CG  1 
ATOM 4825 C CD1 . LEU B 2 585 ? 155.978 164.380 137.113 1.00 92.07  ? 585 LEU A CD1 1 
ATOM 4826 C CD2 . LEU B 2 585 ? 154.213 165.808 138.144 1.00 88.71  ? 585 LEU A CD2 1 
ATOM 4827 N N   . PHE B 2 586 ? 152.070 162.057 136.630 1.00 89.16  ? 586 PHE A N   1 
ATOM 4828 C CA  . PHE B 2 586 ? 151.735 160.938 137.510 1.00 87.78  ? 586 PHE A CA  1 
ATOM 4829 C C   . PHE B 2 586 ? 151.930 159.597 136.805 1.00 87.94  ? 586 PHE A C   1 
ATOM 4830 O O   . PHE B 2 586 ? 152.452 158.639 137.396 1.00 92.03  ? 586 PHE A O   1 
ATOM 4831 C CB  . PHE B 2 586 ? 150.303 161.077 138.018 1.00 87.20  ? 586 PHE A CB  1 
ATOM 4832 C CG  . PHE B 2 586 ? 150.169 162.004 139.186 1.00 92.86  ? 586 PHE A CG  1 
ATOM 4833 C CD1 . PHE B 2 586 ? 151.252 162.263 140.006 1.00 93.97  ? 586 PHE A CD1 1 
ATOM 4834 C CD2 . PHE B 2 586 ? 148.964 162.620 139.464 1.00 93.12  ? 586 PHE A CD2 1 
ATOM 4835 C CE1 . PHE B 2 586 ? 151.136 163.117 141.082 1.00 94.61  ? 586 PHE A CE1 1 
ATOM 4836 C CE2 . PHE B 2 586 ? 148.840 163.475 140.540 1.00 93.50  ? 586 PHE A CE2 1 
ATOM 4837 C CZ  . PHE B 2 586 ? 149.928 163.724 141.350 1.00 94.10  ? 586 PHE A CZ  1 
ATOM 4838 N N   . MET B 2 587 ? 151.554 159.533 135.534 1.00 79.88  ? 587 MET A N   1 
ATOM 4839 C CA  . MET B 2 587 ? 151.727 158.302 134.735 1.00 70.37  ? 587 MET A CA  1 
ATOM 4840 C C   . MET B 2 587 ? 153.202 158.021 134.649 1.00 76.91  ? 587 MET A C   1 
ATOM 4841 O O   . MET B 2 587 ? 153.543 156.913 134.819 1.00 88.57  ? 587 MET A O   1 
ATOM 4842 C CB  . MET B 2 587 ? 151.260 158.444 133.295 1.00 70.07  ? 587 MET A CB  1 
ATOM 4843 C CG  . MET B 2 587 ? 151.564 157.283 132.393 1.00 73.89  ? 587 MET A CG  1 
ATOM 4844 S SD  . MET B 2 587 ? 150.875 155.764 133.063 1.00 100.23 ? 587 MET A SD  1 
ATOM 4845 C CE  . MET B 2 587 ? 149.213 155.843 132.391 1.00 84.03  ? 587 MET A CE  1 
ATOM 4846 N N   . GLY B 2 588 ? 154.026 159.004 134.377 1.00 74.71  ? 588 GLY A N   1 
ATOM 4847 C CA  . GLY B 2 588 ? 155.465 158.818 134.320 1.00 70.12  ? 588 GLY A CA  1 
ATOM 4848 C C   . GLY B 2 588 ? 156.051 158.358 135.638 1.00 72.17  ? 588 GLY A C   1 
ATOM 4849 O O   . GLY B 2 588 ? 157.000 157.572 135.660 1.00 83.45  ? 588 GLY A O   1 
ATOM 4850 N N   . ILE B 2 589 ? 155.502 158.842 136.752 1.00 69.50  ? 589 ILE A N   1 
ATOM 4851 C CA  . ILE B 2 589 ? 155.951 158.377 138.062 1.00 73.55  ? 589 ILE A CA  1 
ATOM 4852 C C   . ILE B 2 589 ? 155.647 156.893 138.230 1.00 76.39  ? 589 ILE A C   1 
ATOM 4853 O O   . ILE B 2 589 ? 156.461 156.132 138.771 1.00 79.44  ? 589 ILE A O   1 
ATOM 4854 C CB  . ILE B 2 589 ? 155.309 159.225 139.176 1.00 70.80  ? 589 ILE A CB  1 
ATOM 4855 C CG1 . ILE B 2 589 ? 156.192 160.429 139.497 1.00 72.01  ? 589 ILE A CG1 1 
ATOM 4856 C CG2 . ILE B 2 589 ? 155.094 158.401 140.429 1.00 74.84  ? 589 ILE A CG2 1 
ATOM 4857 C CD1 . ILE B 2 589 ? 155.593 161.364 140.519 1.00 80.97  ? 589 ILE A CD1 1 
ATOM 4858 N N   . TYR B 2 590 ? 154.474 156.457 137.767 1.00 74.22  ? 590 TYR A N   1 
ATOM 4859 C CA  . TYR B 2 590 ? 154.164 155.027 137.793 1.00 70.31  ? 590 TYR A CA  1 
ATOM 4860 C C   . TYR B 2 590 ? 155.163 154.230 136.959 1.00 67.35  ? 590 TYR A C   1 
ATOM 4861 O O   . TYR B 2 590 ? 155.634 153.159 137.375 1.00 82.46  ? 590 TYR A O   1 
ATOM 4862 C CB  . TYR B 2 590 ? 152.741 154.788 137.292 1.00 66.73  ? 590 TYR A CB  1 
ATOM 4863 C CG  . TYR B 2 590 ? 152.507 153.402 136.733 1.00 62.73  ? 590 TYR A CG  1 
ATOM 4864 C CD1 . TYR B 2 590 ? 152.298 152.320 137.573 1.00 68.45  ? 590 TYR A CD1 1 
ATOM 4865 C CD2 . TYR B 2 590 ? 152.487 153.180 135.363 1.00 61.41  ? 590 TYR A CD2 1 
ATOM 4866 C CE1 . TYR B 2 590 ? 152.082 151.056 137.067 1.00 66.42  ? 590 TYR A CE1 1 
ATOM 4867 C CE2 . TYR B 2 590 ? 152.273 151.919 134.849 1.00 65.38  ? 590 TYR A CE2 1 
ATOM 4868 C CZ  . TYR B 2 590 ? 152.072 150.862 135.706 1.00 67.69  ? 590 TYR A CZ  1 
ATOM 4869 O OH  . TYR B 2 590 ? 151.856 149.604 135.199 1.00 74.76  ? 590 TYR A OH  1 
ATOM 4870 N N   . THR B 2 591 ? 155.498 154.739 135.773 1.00 63.09  ? 591 THR A N   1 
ATOM 4871 C CA  . THR B 2 591 ? 156.467 154.052 134.926 1.00 63.46  ? 591 THR A CA  1 
ATOM 4872 C C   . THR B 2 591 ? 157.830 153.974 135.603 1.00 70.63  ? 591 THR A C   1 
ATOM 4873 O O   . THR B 2 591 ? 158.531 152.963 135.495 1.00 80.90  ? 591 THR A O   1 
ATOM 4874 C CB  . THR B 2 591 ? 156.581 154.754 133.576 1.00 71.11  ? 591 THR A CB  1 
ATOM 4875 O OG1 . THR B 2 591 ? 155.276 154.911 133.011 1.00 91.55  ? 591 THR A OG1 1 
ATOM 4876 C CG2 . THR B 2 591 ? 157.429 153.931 132.627 1.00 72.45  ? 591 THR A CG2 1 
ATOM 4877 N N   . GLY B 2 592 ? 158.222 155.037 136.306 1.00 85.38  ? 592 GLY A N   1 
ATOM 4878 C CA  . GLY B 2 592 ? 159.471 155.004 137.049 1.00 88.33  ? 592 GLY A CA  1 
ATOM 4879 C C   . GLY B 2 592 ? 159.449 153.996 138.181 1.00 85.01  ? 592 GLY A C   1 
ATOM 4880 O O   . GLY B 2 592 ? 160.462 153.350 138.470 1.00 88.62  ? 592 GLY A O   1 
ATOM 4881 N N   . ILE B 2 593 ? 158.303 153.866 138.851 1.00 76.87  ? 593 ILE A N   1 
ATOM 4882 C CA  . ILE B 2 593 ? 158.136 152.814 139.851 1.00 73.64  ? 593 ILE A CA  1 
ATOM 4883 C C   . ILE B 2 593 ? 158.421 151.457 139.226 1.00 65.82  ? 593 ILE A C   1 
ATOM 4884 O O   . ILE B 2 593 ? 159.182 150.643 139.768 1.00 78.72  ? 593 ILE A O   1 
ATOM 4885 C CB  . ILE B 2 593 ? 156.718 152.862 140.447 1.00 72.50  ? 593 ILE A CB  1 
ATOM 4886 C CG1 . ILE B 2 593 ? 156.584 154.007 141.447 1.00 82.92  ? 593 ILE A CG1 1 
ATOM 4887 C CG2 . ILE B 2 593 ? 156.375 151.540 141.111 1.00 58.33  ? 593 ILE A CG2 1 
ATOM 4888 C CD1 . ILE B 2 593 ? 155.156 154.284 141.847 1.00 80.62  ? 593 ILE A CD1 1 
ATOM 4889 N N   . LEU B 2 594 ? 157.819 151.205 138.062 1.00 76.54  ? 594 LEU A N   1 
ATOM 4890 C CA  . LEU B 2 594 ? 158.036 149.935 137.374 1.00 75.44  ? 594 LEU A CA  1 
ATOM 4891 C C   . LEU B 2 594 ? 159.508 149.736 137.031 1.00 77.79  ? 594 LEU A C   1 
ATOM 4892 O O   . LEU B 2 594 ? 160.060 148.644 137.216 1.00 88.82  ? 594 LEU A O   1 
ATOM 4893 C CB  . LEU B 2 594 ? 157.182 149.870 136.109 1.00 76.76  ? 594 LEU A CB  1 
ATOM 4894 C CG  . LEU B 2 594 ? 155.768 149.313 136.261 1.00 82.60  ? 594 LEU A CG  1 
ATOM 4895 C CD1 . LEU B 2 594 ? 155.261 148.821 134.922 1.00 85.10  ? 594 LEU A CD1 1 
ATOM 4896 C CD2 . LEU B 2 594 ? 155.735 148.200 137.289 1.00 84.79  ? 594 LEU A CD2 1 
ATOM 4897 N N   . THR B 2 595 ? 160.159 150.785 136.521 1.00 89.31  ? 595 THR A N   1 
ATOM 4898 C CA  . THR B 2 595 ? 161.555 150.659 136.111 1.00 88.75  ? 595 THR A CA  1 
ATOM 4899 C C   . THR B 2 595 ? 162.461 150.354 137.295 1.00 86.94  ? 595 THR A C   1 
ATOM 4900 O O   . THR B 2 595 ? 163.339 149.489 137.202 1.00 87.18  ? 595 THR A O   1 
ATOM 4901 C CB  . THR B 2 595 ? 162.028 151.929 135.407 1.00 91.09  ? 595 THR A CB  1 
ATOM 4902 O OG1 . THR B 2 595 ? 161.833 153.056 136.269 1.00 93.33  ? 595 THR A OG1 1 
ATOM 4903 C CG2 . THR B 2 595 ? 161.267 152.140 134.113 1.00 89.76  ? 595 THR A CG2 1 
ATOM 4904 N N   . PHE B 2 596 ? 162.277 151.059 138.415 1.00 88.72  ? 596 PHE A N   1 
ATOM 4905 C CA  . PHE B 2 596 ? 163.127 150.789 139.570 1.00 87.50  ? 596 PHE A CA  1 
ATOM 4906 C C   . PHE B 2 596 ? 162.862 149.399 140.130 1.00 93.13  ? 596 PHE A C   1 
ATOM 4907 O O   . PHE B 2 596 ? 163.799 148.708 140.546 1.00 102.73 ? 596 PHE A O   1 
ATOM 4908 C CB  . PHE B 2 596 ? 162.957 151.863 140.651 1.00 97.89  ? 596 PHE A CB  1 
ATOM 4909 C CG  . PHE B 2 596 ? 163.847 153.060 140.439 1.00 102.05 ? 596 PHE A CG  1 
ATOM 4910 C CD1 . PHE B 2 596 ? 163.709 153.843 139.306 1.00 98.80  ? 596 PHE A CD1 1 
ATOM 4911 C CD2 . PHE B 2 596 ? 164.858 153.366 141.335 1.00 105.17 ? 596 PHE A CD2 1 
ATOM 4912 C CE1 . PHE B 2 596 ? 164.528 154.933 139.095 1.00 98.41  ? 596 PHE A CE1 1 
ATOM 4913 C CE2 . PHE B 2 596 ? 165.680 154.456 141.129 1.00 103.00 ? 596 PHE A CE2 1 
ATOM 4914 C CZ  . PHE B 2 596 ? 165.516 155.239 140.006 1.00 101.22 ? 596 PHE A CZ  1 
ATOM 4915 N N   . LEU B 2 597 ? 161.597 148.969 140.156 1.00 87.56  ? 597 LEU A N   1 
ATOM 4916 C CA  . LEU B 2 597 ? 161.310 147.624 140.641 1.00 79.01  ? 597 LEU A CA  1 
ATOM 4917 C C   . LEU B 2 597 ? 161.989 146.575 139.772 1.00 80.44  ? 597 LEU A C   1 
ATOM 4918 O O   . LEU B 2 597 ? 162.563 145.609 140.287 1.00 89.30  ? 597 LEU A O   1 
ATOM 4919 C CB  . LEU B 2 597 ? 159.804 147.383 140.690 1.00 83.22  ? 597 LEU A CB  1 
ATOM 4920 C CG  . LEU B 2 597 ? 159.411 145.940 141.004 1.00 74.74  ? 597 LEU A CG  1 
ATOM 4921 C CD1 . LEU B 2 597 ? 159.590 145.659 142.484 1.00 82.15  ? 597 LEU A CD1 1 
ATOM 4922 C CD2 . LEU B 2 597 ? 157.986 145.663 140.575 1.00 82.21  ? 597 LEU A CD2 1 
ATOM 4923 N N   . ASP B 2 598 ? 161.939 146.750 138.450 1.00 87.27  ? 598 ASP A N   1 
ATOM 4924 C CA  . ASP B 2 598 ? 162.615 145.809 137.562 1.00 85.00  ? 598 ASP A CA  1 
ATOM 4925 C C   . ASP B 2 598 ? 164.124 145.833 137.770 1.00 86.07  ? 598 ASP A C   1 
ATOM 4926 O O   . ASP B 2 598 ? 164.769 144.780 137.813 1.00 100.10 ? 598 ASP A O   1 
ATOM 4927 C CB  . ASP B 2 598 ? 162.274 146.121 136.106 1.00 91.90  ? 598 ASP A CB  1 
ATOM 4928 C CG  . ASP B 2 598 ? 163.278 145.533 135.135 1.00 97.61  ? 598 ASP A CG  1 
ATOM 4929 O OD1 . ASP B 2 598 ? 163.082 144.379 134.703 1.00 97.17  ? 598 ASP A OD1 1 
ATOM 4930 O OD2 . ASP B 2 598 ? 164.261 146.225 134.800 1.00 98.98  ? 598 ASP A OD2 1 
ATOM 4931 N N   . ALA B 2 599 ? 164.706 147.028 137.893 1.00 87.48  ? 599 ALA A N   1 
ATOM 4932 C CA  . ALA B 2 599 ? 166.155 147.133 138.021 1.00 89.63  ? 599 ALA A CA  1 
ATOM 4933 C C   . ALA B 2 599 ? 166.650 146.505 139.317 1.00 89.14  ? 599 ALA A C   1 
ATOM 4934 O O   . ALA B 2 599 ? 167.664 145.798 139.319 1.00 92.09  ? 599 ALA A O   1 
ATOM 4935 C CB  . ALA B 2 599 ? 166.584 148.596 137.938 1.00 98.46  ? 599 ALA A CB  1 
ATOM 4936 N N   . VAL B 2 600 ? 165.953 146.755 140.428 1.00 94.59  ? 600 VAL A N   1 
ATOM 4937 C CA  . VAL B 2 600 ? 166.403 146.236 141.718 1.00 95.90  ? 600 VAL A CA  1 
ATOM 4938 C C   . VAL B 2 600 ? 166.394 144.713 141.708 1.00 99.33  ? 600 VAL A C   1 
ATOM 4939 O O   . VAL B 2 600 ? 167.368 144.065 142.107 1.00 103.68 ? 600 VAL A O   1 
ATOM 4940 C CB  . VAL B 2 600 ? 165.532 146.800 142.854 1.00 97.57  ? 600 VAL A CB  1 
ATOM 4941 C CG1 . VAL B 2 600 ? 165.548 145.869 144.056 1.00 93.93  ? 600 VAL A CG1 1 
ATOM 4942 C CG2 . VAL B 2 600 ? 166.006 148.187 143.243 1.00 94.31  ? 600 VAL A CG2 1 
ATOM 4943 N N   . SER B 2 601 ? 165.296 144.120 141.243 1.00 94.13  ? 601 SER A N   1 
ATOM 4944 C CA  . SER B 2 601 ? 165.172 142.668 141.154 1.00 92.05  ? 601 SER A CA  1 
ATOM 4945 C C   . SER B 2 601 ? 165.399 142.258 139.703 1.00 92.79  ? 601 SER A C   1 
ATOM 4946 O O   . SER B 2 601 ? 164.465 142.036 138.934 1.00 95.62  ? 601 SER A O   1 
ATOM 4947 C CB  . SER B 2 601 ? 163.811 142.214 141.664 1.00 92.52  ? 601 SER A CB  1 
ATOM 4948 O OG  . SER B 2 601 ? 162.809 142.442 140.689 1.00 97.31  ? 601 SER A OG  1 
ATOM 4949 N N   . TRP B 2 602 ? 166.671 142.156 139.330 1.00 98.55  ? 602 TRP A N   1 
ATOM 4950 C CA  . TRP B 2 602 ? 167.060 141.732 137.992 1.00 100.73 ? 602 TRP A CA  1 
ATOM 4951 C C   . TRP B 2 602 ? 167.499 140.275 138.049 1.00 103.94 ? 602 TRP A C   1 
ATOM 4952 O O   . TRP B 2 602 ? 168.507 139.951 138.684 1.00 110.47 ? 602 TRP A O   1 
ATOM 4953 C CB  . TRP B 2 602 ? 168.181 142.610 137.441 1.00 102.32 ? 602 TRP A CB  1 
ATOM 4954 C CG  . TRP B 2 602 ? 168.541 142.283 136.028 1.00 106.92 ? 602 TRP A CG  1 
ATOM 4955 C CD1 . TRP B 2 602 ? 167.811 142.568 134.913 1.00 112.43 ? 602 TRP A CD1 1 
ATOM 4956 C CD2 . TRP B 2 602 ? 169.714 141.599 135.576 1.00 110.03 ? 602 TRP A CD2 1 
ATOM 4957 N NE1 . TRP B 2 602 ? 168.459 142.109 133.793 1.00 110.80 ? 602 TRP A NE1 1 
ATOM 4958 C CE2 . TRP B 2 602 ? 169.630 141.510 134.174 1.00 112.10 ? 602 TRP A CE2 1 
ATOM 4959 C CE3 . TRP B 2 602 ? 170.828 141.057 136.222 1.00 112.20 ? 602 TRP A CE3 1 
ATOM 4960 C CZ2 . TRP B 2 602 ? 170.618 140.900 133.405 1.00 112.61 ? 602 TRP A CZ2 1 
ATOM 4961 C CZ3 . TRP B 2 602 ? 171.807 140.451 135.457 1.00 113.35 ? 602 TRP A CZ3 1 
ATOM 4962 C CH2 . TRP B 2 602 ? 171.696 140.378 134.064 1.00 112.33 ? 602 TRP A CH2 1 
ATOM 4963 N N   . GLY B 2 603 ? 166.744 139.403 137.386 1.00 99.38  ? 603 GLY A N   1 
ATOM 4964 C CA  . GLY B 2 603 ? 167.031 137.987 137.401 1.00 101.12 ? 603 GLY A CA  1 
ATOM 4965 C C   . GLY B 2 603 ? 166.599 137.257 138.652 1.00 100.44 ? 603 GLY A C   1 
ATOM 4966 O O   . GLY B 2 603 ? 166.874 136.058 138.774 1.00 106.97 ? 603 GLY A O   1 
ATOM 4967 N N   . ARG B 2 604 ? 165.934 137.937 139.587 1.00 96.77  ? 604 ARG A N   1 
ATOM 4968 C CA  . ARG B 2 604 ? 165.489 137.332 140.837 1.00 94.71  ? 604 ARG A CA  1 
ATOM 4969 C C   . ARG B 2 604 ? 164.046 137.709 141.145 1.00 97.49  ? 604 ARG A C   1 
ATOM 4970 O O   . ARG B 2 604 ? 163.644 137.729 142.311 1.00 100.83 ? 604 ARG A O   1 
ATOM 4971 C CB  . ARG B 2 604 ? 166.390 137.745 142.001 1.00 92.01  ? 604 ARG A CB  1 
ATOM 4972 C CG  . ARG B 2 604 ? 167.852 137.932 141.649 1.00 98.73  ? 604 ARG A CG  1 
ATOM 4973 C CD  . ARG B 2 604 ? 168.703 138.020 142.902 1.00 102.42 ? 604 ARG A CD  1 
ATOM 4974 N NE  . ARG B 2 604 ? 168.109 138.903 143.898 1.00 102.43 ? 604 ARG A NE  1 
ATOM 4975 C CZ  . ARG B 2 604 ? 168.145 140.227 143.844 1.00 100.03 ? 604 ARG A CZ  1 
ATOM 4976 N NH1 . ARG B 2 604 ? 168.739 140.863 142.848 1.00 98.96  ? 604 ARG A NH1 1 
ATOM 4977 N NH2 . ARG B 2 604 ? 167.572 140.932 144.815 1.00 96.07  ? 604 ARG A NH2 1 
ATOM 4978 N N   . PHE B 2 605 ? 163.255 138.017 140.116 1.00 87.87  ? 605 PHE A N   1 
ATOM 4979 C CA  . PHE B 2 605 ? 161.902 138.503 140.358 1.00 87.69  ? 605 PHE A CA  1 
ATOM 4980 C C   . PHE B 2 605 ? 160.999 137.444 140.974 1.00 94.10  ? 605 PHE A C   1 
ATOM 4981 O O   . PHE B 2 605 ? 160.002 137.798 141.612 1.00 108.33 ? 605 PHE A O   1 
ATOM 4982 C CB  . PHE B 2 605 ? 161.273 139.020 139.067 1.00 86.46  ? 605 PHE A CB  1 
ATOM 4983 C CG  . PHE B 2 605 ? 159.973 139.732 139.284 1.00 85.48  ? 605 PHE A CG  1 
ATOM 4984 C CD1 . PHE B 2 605 ? 159.939 140.933 139.969 1.00 86.97  ? 605 PHE A CD1 1 
ATOM 4985 C CD2 . PHE B 2 605 ? 158.785 139.194 138.829 1.00 85.02  ? 605 PHE A CD2 1 
ATOM 4986 C CE1 . PHE B 2 605 ? 158.749 141.589 140.183 1.00 88.21  ? 605 PHE A CE1 1 
ATOM 4987 C CE2 . PHE B 2 605 ? 157.590 139.848 139.041 1.00 82.55  ? 605 PHE A CE2 1 
ATOM 4988 C CZ  . PHE B 2 605 ? 157.574 141.046 139.719 1.00 88.78  ? 605 PHE A CZ  1 
ATOM 4989 N N   . ALA B 2 606 ? 161.318 136.160 140.799 1.00 93.42  ? 606 ALA A N   1 
ATOM 4990 C CA  . ALA B 2 606 ? 160.511 135.113 141.417 1.00 95.23  ? 606 ALA A CA  1 
ATOM 4991 C C   . ALA B 2 606 ? 160.488 135.249 142.932 1.00 98.93  ? 606 ALA A C   1 
ATOM 4992 O O   . ALA B 2 606 ? 159.532 134.812 143.581 1.00 101.64 ? 606 ALA A O   1 
ATOM 4993 C CB  . ALA B 2 606 ? 161.037 133.737 141.014 1.00 100.60 ? 606 ALA A CB  1 
ATOM 4994 N N   . GLU B 2 607 ? 161.523 135.851 143.508 1.00 101.20 ? 607 GLU A N   1 
ATOM 4995 C CA  . GLU B 2 607 ? 161.584 136.110 144.938 1.00 100.96 ? 607 GLU A CA  1 
ATOM 4996 C C   . GLU B 2 607 ? 160.947 137.438 145.321 1.00 101.41 ? 607 GLU A C   1 
ATOM 4997 O O   . GLU B 2 607 ? 160.978 137.807 146.499 1.00 103.45 ? 607 GLU A O   1 
ATOM 4998 C CB  . GLU B 2 607 ? 163.040 136.080 145.409 1.00 102.14 ? 607 GLU A CB  1 
ATOM 4999 C CG  . GLU B 2 607 ? 163.900 135.082 144.651 1.00 105.95 ? 607 GLU A CG  1 
ATOM 5000 C CD  . GLU B 2 607 ? 165.357 135.133 145.062 1.00 112.78 ? 607 GLU A CD  1 
ATOM 5001 O OE1 . GLU B 2 607 ? 165.691 135.913 145.978 1.00 117.27 ? 607 GLU A OE1 1 
ATOM 5002 O OE2 . GLU B 2 607 ? 166.169 134.393 144.468 1.00 110.23 ? 607 GLU A OE2 1 
ATOM 5003 N N   . PHE B 2 608 ? 160.378 138.161 144.360 1.00 96.21  ? 608 PHE A N   1 
ATOM 5004 C CA  . PHE B 2 608 ? 159.769 139.460 144.608 1.00 93.64  ? 608 PHE A CA  1 
ATOM 5005 C C   . PHE B 2 608 ? 158.281 139.511 144.306 1.00 94.62  ? 608 PHE A C   1 
ATOM 5006 O O   . PHE B 2 608 ? 157.570 140.293 144.939 1.00 102.19 ? 608 PHE A O   1 
ATOM 5007 C CB  . PHE B 2 608 ? 160.466 140.546 143.776 1.00 90.50  ? 608 PHE A CB  1 
ATOM 5008 C CG  . PHE B 2 608 ? 161.783 140.991 144.337 1.00 90.95  ? 608 PHE A CG  1 
ATOM 5009 C CD1 . PHE B 2 608 ? 162.866 140.133 144.359 1.00 94.20  ? 608 PHE A CD1 1 
ATOM 5010 C CD2 . PHE B 2 608 ? 161.939 142.270 144.838 1.00 99.60  ? 608 PHE A CD2 1 
ATOM 5011 C CE1 . PHE B 2 608 ? 164.079 140.541 144.871 1.00 101.82 ? 608 PHE A CE1 1 
ATOM 5012 C CE2 . PHE B 2 608 ? 163.149 142.683 145.352 1.00 100.29 ? 608 PHE A CE2 1 
ATOM 5013 C CZ  . PHE B 2 608 ? 164.220 141.817 145.369 1.00 102.77 ? 608 PHE A CZ  1 
ATOM 5014 N N   . GLY B 2 609 ? 157.794 138.707 143.360 1.00 86.38  ? 609 GLY A N   1 
ATOM 5015 C CA  . GLY B 2 609 ? 156.413 138.840 142.924 1.00 88.09  ? 609 GLY A CA  1 
ATOM 5016 C C   . GLY B 2 609 ? 155.408 138.570 144.027 1.00 91.51  ? 609 GLY A C   1 
ATOM 5017 O O   . GLY B 2 609 ? 154.370 139.232 144.106 1.00 99.53  ? 609 GLY A O   1 
ATOM 5018 N N   . ILE B 2 610 ? 155.696 137.593 144.886 1.00 94.30  ? 610 ILE A N   1 
ATOM 5019 C CA  . ILE B 2 610 ? 154.796 137.286 145.994 1.00 94.17  ? 610 ILE A CA  1 
ATOM 5020 C C   . ILE B 2 610 ? 154.687 138.474 146.941 1.00 95.44  ? 610 ILE A C   1 
ATOM 5021 O O   . ILE B 2 610 ? 153.592 138.831 147.391 1.00 94.99  ? 610 ILE A O   1 
ATOM 5022 C CB  . ILE B 2 610 ? 155.269 136.011 146.716 1.00 97.21  ? 610 ILE A CB  1 
ATOM 5023 C CG1 . ILE B 2 610 ? 156.781 136.066 146.941 1.00 103.82 ? 610 ILE A CG1 1 
ATOM 5024 C CG2 . ILE B 2 610 ? 154.874 134.773 145.927 1.00 90.51  ? 610 ILE A CG2 1 
ATOM 5025 C CD1 . ILE B 2 610 ? 157.364 134.806 147.524 1.00 101.94 ? 610 ILE A CD1 1 
ATOM 5026 N N   . TRP B 2 611 ? 155.818 139.108 147.256 1.00 109.02 ? 611 TRP A N   1 
ATOM 5027 C CA  . TRP B 2 611 ? 155.788 140.295 148.103 1.00 107.46 ? 611 TRP A CA  1 
ATOM 5028 C C   . TRP B 2 611 ? 155.192 141.491 147.372 1.00 106.02 ? 611 TRP A C   1 
ATOM 5029 O O   . TRP B 2 611 ? 154.574 142.355 148.002 1.00 108.96 ? 611 TRP A O   1 
ATOM 5030 C CB  . TRP B 2 611 ? 157.198 140.619 148.597 1.00 111.39 ? 611 TRP A CB  1 
ATOM 5031 C CG  . TRP B 2 611 ? 157.364 142.024 149.089 1.00 116.08 ? 611 TRP A CG  1 
ATOM 5032 C CD1 . TRP B 2 611 ? 156.870 142.551 150.246 1.00 114.25 ? 611 TRP A CD1 1 
ATOM 5033 C CD2 . TRP B 2 611 ? 158.082 143.081 148.441 1.00 116.54 ? 611 TRP A CD2 1 
ATOM 5034 N NE1 . TRP B 2 611 ? 157.231 143.871 150.357 1.00 115.24 ? 611 TRP A NE1 1 
ATOM 5035 C CE2 . TRP B 2 611 ? 157.976 144.221 149.262 1.00 117.72 ? 611 TRP A CE2 1 
ATOM 5036 C CE3 . TRP B 2 611 ? 158.801 143.175 147.247 1.00 110.87 ? 611 TRP A CE3 1 
ATOM 5037 C CZ2 . TRP B 2 611 ? 158.563 145.439 148.927 1.00 114.52 ? 611 TRP A CZ2 1 
ATOM 5038 C CZ3 . TRP B 2 611 ? 159.383 144.386 146.916 1.00 114.02 ? 611 TRP A CZ3 1 
ATOM 5039 C CH2 . TRP B 2 611 ? 159.262 145.500 147.752 1.00 115.67 ? 611 TRP A CH2 1 
ATOM 5040 N N   . TRP B 2 612 ? 155.357 141.553 146.052 1.00 94.08  ? 612 TRP A N   1 
ATOM 5041 C CA  . TRP B 2 612 ? 154.918 142.718 145.292 1.00 91.17  ? 612 TRP A CA  1 
ATOM 5042 C C   . TRP B 2 612 ? 153.405 142.723 145.096 1.00 91.12  ? 612 TRP A C   1 
ATOM 5043 O O   . TRP B 2 612 ? 152.717 143.651 145.531 1.00 103.16 ? 612 TRP A O   1 
ATOM 5044 C CB  . TRP B 2 612 ? 155.636 142.756 143.941 1.00 91.71  ? 612 TRP A CB  1 
ATOM 5045 C CG  . TRP B 2 612 ? 155.249 143.913 143.079 1.00 89.90  ? 612 TRP A CG  1 
ATOM 5046 C CD1 . TRP B 2 612 ? 154.535 143.867 141.920 1.00 91.22  ? 612 TRP A CD1 1 
ATOM 5047 C CD2 . TRP B 2 612 ? 155.564 145.292 143.302 1.00 95.05  ? 612 TRP A CD2 1 
ATOM 5048 N NE1 . TRP B 2 612 ? 154.380 145.131 141.408 1.00 92.18  ? 612 TRP A NE1 1 
ATOM 5049 C CE2 . TRP B 2 612 ? 155.003 146.024 142.239 1.00 91.88  ? 612 TRP A CE2 1 
ATOM 5050 C CE3 . TRP B 2 612 ? 156.263 145.979 144.298 1.00 98.27  ? 612 TRP A CE3 1 
ATOM 5051 C CZ2 . TRP B 2 612 ? 155.120 147.406 142.143 1.00 93.85  ? 612 TRP A CZ2 1 
ATOM 5052 C CZ3 . TRP B 2 612 ? 156.377 147.350 144.201 1.00 95.50  ? 612 TRP A CZ3 1 
ATOM 5053 C CH2 . TRP B 2 612 ? 155.809 148.050 143.132 1.00 94.57  ? 612 TRP A CH2 1 
ATOM 5054 N N   . GLU B 2 613 ? 152.879 141.715 144.428 1.00 91.72  ? 613 GLU A N   1 
ATOM 5055 C CA  . GLU B 2 613 ? 151.447 141.690 144.076 1.00 96.79  ? 613 GLU A CA  1 
ATOM 5056 C C   . GLU B 2 613 ? 150.568 141.636 145.317 1.00 104.12 ? 613 GLU A C   1 
ATOM 5057 O O   . GLU B 2 613 ? 149.551 142.324 145.304 1.00 106.41 ? 613 GLU A O   1 
ATOM 5058 C CB  . GLU B 2 613 ? 151.138 140.475 143.230 1.00 98.37  ? 613 GLU A CB  1 
ATOM 5059 C CG  . GLU B 2 613 ? 151.791 140.506 141.856 1.00 101.29 ? 613 GLU A CG  1 
ATOM 5060 C CD  . GLU B 2 613 ? 151.264 139.346 141.048 1.00 110.60 ? 613 GLU A CD  1 
ATOM 5061 O OE1 . GLU B 2 613 ? 150.914 138.354 141.703 1.00 116.88 ? 613 GLU A OE1 1 
ATOM 5062 O OE2 . GLU B 2 613 ? 151.170 139.422 139.816 1.00 110.29 ? 613 GLU A OE2 1 
ATOM 5063 N N   . THR B 2 614 ? 150.908 140.841 146.322 1.00 109.12 ? 614 THR A N   1 
ATOM 5064 C CA  . THR B 2 614 ? 150.129 140.750 147.556 1.00 108.48 ? 614 THR A CA  1 
ATOM 5065 C C   . THR B 2 614 ? 150.695 141.697 148.614 1.00 109.59 ? 614 THR A C   1 
ATOM 5066 O O   . THR B 2 614 ? 151.021 141.313 149.736 1.00 109.60 ? 614 THR A O   1 
ATOM 5067 C CB  . THR B 2 614 ? 150.100 139.312 148.058 1.00 105.29 ? 614 THR A CB  1 
ATOM 5068 O OG1 . THR B 2 614 ? 151.423 138.910 148.433 1.00 111.15 ? 614 THR A OG1 1 
ATOM 5069 C CG2 . THR B 2 614 ? 149.583 138.384 146.972 1.00 105.03 ? 614 THR A CG2 1 
ATOM 5070 N N   . GLY B 2 615 ? 150.806 142.966 148.229 1.00 109.95 ? 615 GLY A N   1 
ATOM 5071 C CA  . GLY B 2 615 ? 151.350 143.982 149.101 1.00 109.42 ? 615 GLY A CA  1 
ATOM 5072 C C   . GLY B 2 615 ? 150.779 145.340 148.759 1.00 111.04 ? 615 GLY A C   1 
ATOM 5073 O O   . GLY B 2 615 ? 149.943 145.479 147.865 1.00 114.72 ? 615 GLY A O   1 
ATOM 5074 N N   . SER B 2 616 ? 151.242 146.352 149.492 1.00 120.28 ? 616 SER A N   1 
ATOM 5075 C CA  . SER B 2 616 ? 150.750 147.708 149.287 1.00 124.91 ? 616 SER A CA  1 
ATOM 5076 C C   . SER B 2 616 ? 151.322 148.348 148.030 1.00 122.70 ? 616 SER A C   1 
ATOM 5077 O O   . SER B 2 616 ? 150.663 149.200 147.422 1.00 122.24 ? 616 SER A O   1 
ATOM 5078 C CB  . SER B 2 616 ? 151.076 148.570 150.506 1.00 125.06 ? 616 SER A CB  1 
ATOM 5079 O OG  . SER B 2 616 ? 152.410 148.357 150.932 1.00 122.91 ? 616 SER A OG  1 
ATOM 5080 N N   . GLY B 2 617 ? 152.535 147.961 147.631 1.00 113.11 ? 617 GLY A N   1 
ATOM 5081 C CA  . GLY B 2 617 ? 153.166 148.596 146.484 1.00 113.76 ? 617 GLY A CA  1 
ATOM 5082 C C   . GLY B 2 617 ? 152.383 148.408 145.200 1.00 110.33 ? 617 GLY A C   1 
ATOM 5083 O O   . GLY B 2 617 ? 152.261 149.335 144.393 1.00 120.60 ? 617 GLY A O   1 
ATOM 5084 N N   . CYS B 2 618 ? 151.846 147.206 144.988 1.00 98.52  ? 618 CYS A N   1 
ATOM 5085 C CA  . CYS B 2 618 ? 151.046 146.971 143.793 1.00 100.16 ? 618 CYS A CA  1 
ATOM 5086 C C   . CYS B 2 618 ? 149.765 147.792 143.824 1.00 102.54 ? 618 CYS A C   1 
ATOM 5087 O O   . CYS B 2 618 ? 149.320 148.297 142.787 1.00 107.60 ? 618 CYS A O   1 
ATOM 5088 C CB  . CYS B 2 618 ? 150.731 145.485 143.651 1.00 108.31 ? 618 CYS A CB  1 
ATOM 5089 S SG  . CYS B 2 618 ? 150.651 144.948 141.937 1.00 133.21 ? 618 CYS A SG  1 
ATOM 5090 N N   . LYS B 2 619 ? 149.163 147.942 145.005 1.00 101.90 ? 619 LYS A N   1 
ATOM 5091 C CA  . LYS B 2 619 ? 147.996 148.808 145.128 1.00 104.61 ? 619 LYS A CA  1 
ATOM 5092 C C   . LYS B 2 619 ? 148.344 150.243 144.759 1.00 106.76 ? 619 LYS A C   1 
ATOM 5093 O O   . LYS B 2 619 ? 147.588 150.909 144.041 1.00 114.10 ? 619 LYS A O   1 
ATOM 5094 C CB  . LYS B 2 619 ? 147.438 148.742 146.549 1.00 100.35 ? 619 LYS A CB  1 
ATOM 5095 C CG  . LYS B 2 619 ? 146.654 147.478 146.853 1.00 105.24 ? 619 LYS A CG  1 
ATOM 5096 C CD  . LYS B 2 619 ? 146.084 147.515 148.260 1.00 105.48 ? 619 LYS A CD  1 
ATOM 5097 C CE  . LYS B 2 619 ? 146.214 146.169 148.948 1.00 107.79 ? 619 LYS A CE  1 
ATOM 5098 N NZ  . LYS B 2 619 ? 147.637 145.763 149.097 1.00 111.36 ? 619 LYS A NZ  1 
ATOM 5099 N N   . VAL B 2 620 ? 149.494 150.729 145.231 1.00 96.76  ? 620 VAL A N   1 
ATOM 5100 C CA  . VAL B 2 620 ? 149.913 152.093 144.921 1.00 95.28  ? 620 VAL A CA  1 
ATOM 5101 C C   . VAL B 2 620 ? 150.104 152.260 143.420 1.00 94.77  ? 620 VAL A C   1 
ATOM 5102 O O   . VAL B 2 620 ? 149.635 153.234 142.819 1.00 100.37 ? 620 VAL A O   1 
ATOM 5103 C CB  . VAL B 2 620 ? 151.202 152.446 145.683 1.00 92.26  ? 620 VAL A CB  1 
ATOM 5104 C CG1 . VAL B 2 620 ? 151.689 153.824 145.281 1.00 91.55  ? 620 VAL A CG1 1 
ATOM 5105 C CG2 . VAL B 2 620 ? 150.980 152.369 147.176 1.00 99.29  ? 620 VAL A CG2 1 
ATOM 5106 N N   . ALA B 2 621 ? 150.803 151.312 142.793 1.00 83.86  ? 621 ALA A N   1 
ATOM 5107 C CA  . ALA B 2 621 ? 151.073 151.419 141.364 1.00 74.08  ? 621 ALA A CA  1 
ATOM 5108 C C   . ALA B 2 621 ? 149.786 151.374 140.551 1.00 79.21  ? 621 ALA A C   1 
ATOM 5109 O O   . ALA B 2 621 ? 149.610 152.156 139.607 1.00 97.19  ? 621 ALA A O   1 
ATOM 5110 C CB  . ALA B 2 621 ? 152.025 150.308 140.925 1.00 84.56  ? 621 ALA A CB  1 
ATOM 5111 N N   . GLY B 2 622 ? 148.873 150.467 140.902 1.00 84.80  ? 622 GLY A N   1 
ATOM 5112 C CA  . GLY B 2 622 ? 147.618 150.384 140.177 1.00 92.11  ? 622 GLY A CA  1 
ATOM 5113 C C   . GLY B 2 622 ? 146.776 151.632 140.332 1.00 91.35  ? 622 GLY A C   1 
ATOM 5114 O O   . GLY B 2 622 ? 146.194 152.126 139.360 1.00 92.46  ? 622 GLY A O   1 
ATOM 5115 N N   . PHE B 2 623 ? 146.703 152.166 141.554 1.00 93.13  ? 623 PHE A N   1 
ATOM 5116 C CA  . PHE B 2 623 ? 145.968 153.404 141.763 1.00 93.02  ? 623 PHE A CA  1 
ATOM 5117 C C   . PHE B 2 623 ? 146.578 154.540 140.958 1.00 93.57  ? 623 PHE A C   1 
ATOM 5118 O O   . PHE B 2 623 ? 145.854 155.321 140.334 1.00 97.45  ? 623 PHE A O   1 
ATOM 5119 C CB  . PHE B 2 623 ? 145.933 153.763 143.246 1.00 89.46  ? 623 PHE A CB  1 
ATOM 5120 C CG  . PHE B 2 623 ? 145.220 155.049 143.531 1.00 95.63  ? 623 PHE A CG  1 
ATOM 5121 C CD1 . PHE B 2 623 ? 143.843 155.080 143.636 1.00 99.54  ? 623 PHE A CD1 1 
ATOM 5122 C CD2 . PHE B 2 623 ? 145.924 156.229 143.678 1.00 94.07  ? 623 PHE A CD2 1 
ATOM 5123 C CE1 . PHE B 2 623 ? 143.182 156.261 143.889 1.00 97.19  ? 623 PHE A CE1 1 
ATOM 5124 C CE2 . PHE B 2 623 ? 145.267 157.412 143.930 1.00 95.64  ? 623 PHE A CE2 1 
ATOM 5125 C CZ  . PHE B 2 623 ? 143.895 157.429 144.037 1.00 96.98  ? 623 PHE A CZ  1 
ATOM 5126 N N   . LEU B 2 624 ? 147.908 154.644 140.953 1.00 82.80  ? 624 LEU A N   1 
ATOM 5127 C CA  . LEU B 2 624 ? 148.561 155.707 140.199 1.00 73.43  ? 624 LEU A CA  1 
ATOM 5128 C C   . LEU B 2 624 ? 148.233 155.604 138.717 1.00 74.30  ? 624 LEU A C   1 
ATOM 5129 O O   . LEU B 2 624 ? 147.845 156.593 138.085 1.00 92.76  ? 624 LEU A O   1 
ATOM 5130 C CB  . LEU B 2 624 ? 150.071 155.650 140.419 1.00 76.32  ? 624 LEU A CB  1 
ATOM 5131 C CG  . LEU B 2 624 ? 150.623 156.528 141.538 1.00 78.16  ? 624 LEU A CG  1 
ATOM 5132 C CD1 . LEU B 2 624 ? 152.133 156.587 141.460 1.00 80.72  ? 624 LEU A CD1 1 
ATOM 5133 C CD2 . LEU B 2 624 ? 150.030 157.920 141.458 1.00 76.00  ? 624 LEU A CD2 1 
ATOM 5134 N N   . ALA B 2 625 ? 148.301 154.409 138.173 1.00 72.24  ? 625 ALA A N   1 
ATOM 5135 C CA  . ALA B 2 625 ? 148.069 154.194 136.743 1.00 70.67  ? 625 ALA A CA  1 
ATOM 5136 C C   . ALA B 2 625 ? 146.655 154.539 136.406 1.00 86.59  ? 625 ALA A C   1 
ATOM 5137 O O   . ALA B 2 625 ? 146.475 155.206 135.436 1.00 99.06  ? 625 ALA A O   1 
ATOM 5138 C CB  . ALA B 2 625 ? 148.226 152.777 136.399 1.00 79.18  ? 625 ALA A CB  1 
ATOM 5139 N N   . VAL B 2 626 ? 145.705 153.994 137.123 1.00 85.48  ? 626 VAL A N   1 
ATOM 5140 C CA  . VAL B 2 626 ? 144.296 154.210 136.810 1.00 81.29  ? 626 VAL A CA  1 
ATOM 5141 C C   . VAL B 2 626 ? 143.928 155.677 136.979 1.00 81.49  ? 626 VAL A C   1 
ATOM 5142 O O   . VAL B 2 626 ? 143.254 156.265 136.123 1.00 91.19  ? 626 VAL A O   1 
ATOM 5143 C CB  . VAL B 2 626 ? 143.409 153.300 137.679 1.00 81.86  ? 626 VAL A CB  1 
ATOM 5144 C CG1 . VAL B 2 626 ? 141.948 153.664 137.502 1.00 89.68  ? 626 VAL A CG1 1 
ATOM 5145 C CG2 . VAL B 2 626 ? 143.637 151.845 137.318 1.00 89.23  ? 626 VAL A CG2 1 
ATOM 5146 N N   . PHE B 2 627 ? 144.367 156.294 138.079 1.00 79.04  ? 627 PHE A N   1 
ATOM 5147 C CA  . PHE B 2 627 ? 144.039 157.691 138.328 1.00 86.49  ? 627 PHE A CA  1 
ATOM 5148 C C   . PHE B 2 627 ? 144.609 158.593 137.247 1.00 84.88  ? 627 PHE A C   1 
ATOM 5149 O O   . PHE B 2 627 ? 143.915 159.483 136.749 1.00 92.04  ? 627 PHE A O   1 
ATOM 5150 C CB  . PHE B 2 627 ? 144.557 158.108 139.704 1.00 89.47  ? 627 PHE A CB  1 
ATOM 5151 C CG  . PHE B 2 627 ? 144.561 159.592 139.927 1.00 91.67  ? 627 PHE A CG  1 
ATOM 5152 C CD1 . PHE B 2 627 ? 143.389 160.265 140.219 1.00 98.74  ? 627 PHE A CD1 1 
ATOM 5153 C CD2 . PHE B 2 627 ? 145.740 160.313 139.857 1.00 80.23  ? 627 PHE A CD2 1 
ATOM 5154 C CE1 . PHE B 2 627 ? 143.391 161.629 140.428 1.00 94.66  ? 627 PHE A CE1 1 
ATOM 5155 C CE2 . PHE B 2 627 ? 145.747 161.676 140.066 1.00 85.59  ? 627 PHE A CE2 1 
ATOM 5156 C CZ  . PHE B 2 627 ? 144.572 162.334 140.351 1.00 90.67  ? 627 PHE A CZ  1 
ATOM 5157 N N   . SER B 2 628 ? 145.867 158.374 136.861 1.00 80.82  ? 628 SER A N   1 
ATOM 5158 C CA  . SER B 2 628 ? 146.475 159.219 135.842 1.00 79.29  ? 628 SER A CA  1 
ATOM 5159 C C   . SER B 2 628 ? 145.755 159.076 134.508 1.00 80.10  ? 628 SER A C   1 
ATOM 5160 O O   . SER B 2 628 ? 145.449 160.075 133.847 1.00 97.20  ? 628 SER A O   1 
ATOM 5161 C CB  . SER B 2 628 ? 147.953 158.876 135.695 1.00 86.02  ? 628 SER A CB  1 
ATOM 5162 O OG  . SER B 2 628 ? 148.138 157.971 134.627 1.00 93.47  ? 628 SER A OG  1 
ATOM 5163 N N   . SER B 2 629 ? 145.465 157.838 134.098 1.00 71.92  ? 629 SER A N   1 
ATOM 5164 C CA  . SER B 2 629 ? 144.803 157.634 132.812 1.00 82.34  ? 629 SER A CA  1 
ATOM 5165 C C   . SER B 2 629 ? 143.413 158.262 132.800 1.00 99.26  ? 629 SER A C   1 
ATOM 5166 O O   . SER B 2 629 ? 143.041 158.970 131.851 1.00 102.84 ? 629 SER A O   1 
ATOM 5167 C CB  . SER B 2 629 ? 144.726 156.142 132.496 1.00 83.69  ? 629 SER A CB  1 
ATOM 5168 O OG  . SER B 2 629 ? 144.429 155.394 133.660 1.00 90.43  ? 629 SER A OG  1 
ATOM 5169 N N   . GLU B 2 630 ? 142.628 158.019 133.854 1.00 110.57 ? 630 GLU A N   1 
ATOM 5170 C CA  . GLU B 2 630 ? 141.277 158.566 133.904 1.00 102.92 ? 630 GLU A CA  1 
ATOM 5171 C C   . GLU B 2 630 ? 141.297 160.087 133.959 1.00 102.97 ? 630 GLU A C   1 
ATOM 5172 O O   . GLU B 2 630 ? 140.487 160.747 133.298 1.00 108.91 ? 630 GLU A O   1 
ATOM 5173 C CB  . GLU B 2 630 ? 140.523 157.992 135.101 1.00 103.61 ? 630 GLU A CB  1 
ATOM 5174 C CG  . GLU B 2 630 ? 140.248 156.503 134.995 1.00 106.42 ? 630 GLU A CG  1 
ATOM 5175 C CD  . GLU B 2 630 ? 139.875 156.081 133.590 1.00 112.28 ? 630 GLU A CD  1 
ATOM 5176 O OE1 . GLU B 2 630 ? 138.808 156.510 133.106 1.00 118.26 ? 630 GLU A OE1 1 
ATOM 5177 O OE2 . GLU B 2 630 ? 140.647 155.322 132.969 1.00 112.63 ? 630 GLU A OE2 1 
ATOM 5178 N N   . SER B 2 631 ? 142.212 160.664 134.744 1.00 90.97  ? 631 SER A N   1 
ATOM 5179 C CA  . SER B 2 631 ? 142.309 162.115 134.817 1.00 89.86  ? 631 SER A CA  1 
ATOM 5180 C C   . SER B 2 631 ? 142.679 162.705 133.466 1.00 93.98  ? 631 SER A C   1 
ATOM 5181 O O   . SER B 2 631 ? 142.112 163.721 133.053 1.00 104.41 ? 631 SER A O   1 
ATOM 5182 C CB  . SER B 2 631 ? 143.331 162.520 135.877 1.00 91.29  ? 631 SER A CB  1 
ATOM 5183 O OG  . SER B 2 631 ? 143.914 163.771 135.562 1.00 95.89  ? 631 SER A OG  1 
ATOM 5184 N N   . ALA B 2 632 ? 143.622 162.079 132.759 1.00 94.84  ? 632 ALA A N   1 
ATOM 5185 C CA  . ALA B 2 632 ? 143.996 162.578 131.441 1.00 94.43  ? 632 ALA A CA  1 
ATOM 5186 C C   . ALA B 2 632 ? 142.814 162.540 130.484 1.00 96.40  ? 632 ALA A C   1 
ATOM 5187 O O   . ALA B 2 632 ? 142.562 163.511 129.762 1.00 101.79 ? 632 ALA A O   1 
ATOM 5188 C CB  . ALA B 2 632 ? 145.164 161.768 130.882 1.00 97.70  ? 632 ALA A CB  1 
ATOM 5189 N N   . ILE B 2 633 ? 142.066 161.435 130.476 1.00 98.64  ? 633 ILE A N   1 
ATOM 5190 C CA  . ILE B 2 633 ? 140.939 161.325 129.551 1.00 102.92 ? 633 ILE A CA  1 
ATOM 5191 C C   . ILE B 2 633 ? 139.860 162.355 129.882 1.00 105.95 ? 633 ILE A C   1 
ATOM 5192 O O   . ILE B 2 633 ? 139.324 163.028 128.989 1.00 107.08 ? 633 ILE A O   1 
ATOM 5193 C CB  . ILE B 2 633 ? 140.384 159.890 129.559 1.00 102.76 ? 633 ILE A CB  1 
ATOM 5194 C CG1 . ILE B 2 633 ? 141.147 159.027 128.555 1.00 102.11 ? 633 ILE A CG1 1 
ATOM 5195 C CG2 . ILE B 2 633 ? 138.900 159.882 129.234 1.00 108.27 ? 633 ILE A CG2 1 
ATOM 5196 C CD1 . ILE B 2 633 ? 140.770 157.567 128.598 1.00 105.88 ? 633 ILE A CD1 1 
ATOM 5197 N N   . PHE B 2 634 ? 139.528 162.502 131.167 1.00 104.46 ? 634 PHE A N   1 
ATOM 5198 C CA  . PHE B 2 634 ? 138.480 163.441 131.552 1.00 98.76  ? 634 PHE A CA  1 
ATOM 5199 C C   . PHE B 2 634 ? 138.895 164.881 131.276 1.00 102.24 ? 634 PHE A C   1 
ATOM 5200 O O   . PHE B 2 634 ? 138.078 165.694 130.827 1.00 111.25 ? 634 PHE A O   1 
ATOM 5201 C CB  . PHE B 2 634 ? 138.121 163.249 133.025 1.00 98.44  ? 634 PHE A CB  1 
ATOM 5202 C CG  . PHE B 2 634 ? 137.583 161.882 133.344 1.00 106.21 ? 634 PHE A CG  1 
ATOM 5203 C CD1 . PHE B 2 634 ? 137.065 161.075 132.346 1.00 105.57 ? 634 PHE A CD1 1 
ATOM 5204 C CD2 . PHE B 2 634 ? 137.603 161.402 134.641 1.00 109.89 ? 634 PHE A CD2 1 
ATOM 5205 C CE1 . PHE B 2 634 ? 136.574 159.818 132.636 1.00 105.17 ? 634 PHE A CE1 1 
ATOM 5206 C CE2 . PHE B 2 634 ? 137.113 160.145 134.937 1.00 109.04 ? 634 PHE A CE2 1 
ATOM 5207 C CZ  . PHE B 2 634 ? 136.598 159.353 133.933 1.00 106.31 ? 634 PHE A CZ  1 
ATOM 5208 N N   . LEU B 2 635 ? 140.161 165.218 131.535 1.00 97.05  ? 635 LEU A N   1 
ATOM 5209 C CA  . LEU B 2 635 ? 140.639 166.558 131.226 1.00 93.75  ? 635 LEU A CA  1 
ATOM 5210 C C   . LEU B 2 635 ? 140.670 166.754 129.719 1.00 98.43  ? 635 LEU A C   1 
ATOM 5211 O O   . LEU B 2 635 ? 140.435 167.865 129.238 1.00 107.17 ? 635 LEU A O   1 
ATOM 5212 C CB  . LEU B 2 635 ? 142.024 166.772 131.828 1.00 94.64  ? 635 LEU A CB  1 
ATOM 5213 C CG  . LEU B 2 635 ? 142.030 166.891 133.349 1.00 92.86  ? 635 LEU A CG  1 
ATOM 5214 C CD1 . LEU B 2 635 ? 143.413 166.606 133.901 1.00 100.00 ? 635 LEU A CD1 1 
ATOM 5215 C CD2 . LEU B 2 635 ? 141.550 168.265 133.768 1.00 92.46  ? 635 LEU A CD2 1 
ATOM 5216 N N   . LEU B 2 636 ? 140.923 165.679 128.965 1.00 109.16 ? 636 LEU A N   1 
ATOM 5217 C CA  . LEU B 2 636 ? 140.917 165.760 127.484 1.00 110.30 ? 636 LEU A CA  1 
ATOM 5218 C C   . LEU B 2 636 ? 139.480 166.079 127.048 1.00 120.29 ? 636 LEU A C   1 
ATOM 5219 O O   . LEU B 2 636 ? 139.360 166.898 126.135 1.00 124.47 ? 636 LEU A O   1 
ATOM 5220 C CB  . LEU B 2 636 ? 141.445 164.490 126.816 1.00 110.75 ? 636 LEU A CB  1 
ATOM 5221 C CG  . LEU B 2 636 ? 141.590 164.528 125.289 1.00 114.97 ? 636 LEU A CG  1 
ATOM 5222 C CD1 . LEU B 2 636 ? 142.457 165.679 124.809 1.00 115.63 ? 636 LEU A CD1 1 
ATOM 5223 C CD2 . LEU B 2 636 ? 142.151 163.212 124.779 1.00 118.96 ? 636 LEU A CD2 1 
ATOM 5224 N N   . MET B 2 637 ? 138.445 165.464 127.644 1.00 126.95 ? 637 MET A N   1 
ATOM 5225 C CA  . MET B 2 637 ? 137.054 165.794 127.338 1.00 121.76 ? 637 MET A CA  1 
ATOM 5226 C C   . MET B 2 637 ? 136.672 167.219 127.724 1.00 117.65 ? 637 MET A C   1 
ATOM 5227 O O   . MET B 2 637 ? 135.980 167.917 126.969 1.00 117.81 ? 637 MET A O   1 
ATOM 5228 C CB  . MET B 2 637 ? 136.155 164.783 128.049 1.00 122.68 ? 637 MET A CB  1 
ATOM 5229 C CG  . MET B 2 637 ? 134.821 165.349 128.509 1.00 124.56 ? 637 MET A CG  1 
ATOM 5230 S SD  . MET B 2 637 ? 133.906 164.218 129.572 1.00 142.79 ? 637 MET A SD  1 
ATOM 5231 C CE  . MET B 2 637 ? 132.291 164.993 129.575 1.00 127.69 ? 637 MET A CE  1 
ATOM 5232 N N   . LEU B 2 638 ? 137.120 167.667 128.898 1.00 112.83 ? 638 LEU A N   1 
ATOM 5233 C CA  . LEU B 2 638 ? 136.839 169.033 129.326 1.00 113.35 ? 638 LEU A CA  1 
ATOM 5234 C C   . LEU B 2 638 ? 137.474 170.048 128.384 1.00 114.91 ? 638 LEU A C   1 
ATOM 5235 O O   . LEU B 2 638 ? 136.873 171.084 128.081 1.00 121.10 ? 638 LEU A O   1 
ATOM 5236 C CB  . LEU B 2 638 ? 137.331 169.245 130.756 1.00 113.15 ? 638 LEU A CB  1 
ATOM 5237 C CG  . LEU B 2 638 ? 136.464 168.645 131.862 1.00 115.92 ? 638 LEU A CG  1 
ATOM 5238 C CD1 . LEU B 2 638 ? 136.884 169.193 133.210 1.00 116.63 ? 638 LEU A CD1 1 
ATOM 5239 C CD2 . LEU B 2 638 ? 134.995 168.923 131.603 1.00 117.26 ? 638 LEU A CD2 1 
ATOM 5240 N N   . ALA B 2 639 ? 138.697 169.774 127.924 1.00 115.75 ? 639 ALA A N   1 
ATOM 5241 C CA  . ALA B 2 639 ? 139.351 170.669 126.976 1.00 115.26 ? 639 ALA A CA  1 
ATOM 5242 C C   . ALA B 2 639 ? 138.585 170.734 125.664 1.00 116.72 ? 639 ALA A C   1 
ATOM 5243 O O   . ALA B 2 639 ? 138.458 171.807 125.064 1.00 118.57 ? 639 ALA A O   1 
ATOM 5244 C CB  . ALA B 2 639 ? 140.791 170.219 126.736 1.00 116.80 ? 639 ALA A CB  1 
ATOM 5245 N N   . THR B 2 640 ? 138.029 169.596 125.232 1.00 131.42 ? 640 THR A N   1 
ATOM 5246 C CA  . THR B 2 640 ? 137.248 169.512 123.981 1.00 136.35 ? 640 THR A CA  1 
ATOM 5247 C C   . THR B 2 640 ? 135.970 170.307 124.142 1.00 138.65 ? 640 THR A C   1 
ATOM 5248 O O   . THR B 2 640 ? 135.549 170.894 123.138 1.00 136.91 ? 640 THR A O   1 
ATOM 5249 C CB  . THR B 2 640 ? 136.957 168.050 123.646 1.00 138.81 ? 640 THR A CB  1 
ATOM 5250 O OG1 . THR B 2 640 ? 138.220 167.392 123.695 1.00 139.47 ? 640 THR A OG1 1 
ATOM 5251 C CG2 . THR B 2 640 ? 136.335 167.875 122.272 1.00 139.41 ? 640 THR A CG2 1 
ATOM 5252 N N   . VAL B 2 641 ? 135.330 170.284 125.318 1.00 133.76 ? 641 VAL A N   1 
ATOM 5253 C CA  . VAL B 2 641 ? 134.124 171.067 125.577 1.00 128.45 ? 641 VAL A CA  1 
ATOM 5254 C C   . VAL B 2 641 ? 134.388 172.568 125.591 1.00 127.69 ? 641 VAL A C   1 
ATOM 5255 O O   . VAL B 2 641 ? 133.630 173.357 125.009 1.00 131.79 ? 641 VAL A O   1 
ATOM 5256 C CB  . VAL B 2 641 ? 133.453 170.593 126.880 1.00 130.58 ? 641 VAL A CB  1 
ATOM 5257 C CG1 . VAL B 2 641 ? 132.570 171.686 127.460 1.00 129.48 ? 641 VAL A CG1 1 
ATOM 5258 C CG2 . VAL B 2 641 ? 132.645 169.332 126.625 1.00 129.14 ? 641 VAL A CG2 1 
ATOM 5259 N N   . GLU B 2 642 ? 135.469 172.985 126.253 1.00 135.18 ? 642 GLU A N   1 
ATOM 5260 C CA  . GLU B 2 642 ? 135.818 174.401 126.293 1.00 137.96 ? 642 GLU A CA  1 
ATOM 5261 C C   . GLU B 2 642 ? 136.213 174.938 124.922 1.00 138.50 ? 642 GLU A C   1 
ATOM 5262 O O   . GLU B 2 642 ? 135.925 176.091 124.586 1.00 138.87 ? 642 GLU A O   1 
ATOM 5263 C CB  . GLU B 2 642 ? 136.983 174.623 127.257 1.00 140.74 ? 642 GLU A CB  1 
ATOM 5264 C CG  . GLU B 2 642 ? 137.387 176.075 127.420 1.00 140.86 ? 642 GLU A CG  1 
ATOM 5265 C CD  . GLU B 2 642 ? 138.258 176.575 126.283 1.00 143.36 ? 642 GLU A CD  1 
ATOM 5266 O OE1 . GLU B 2 642 ? 138.933 175.744 125.638 1.00 144.03 ? 642 GLU A OE1 1 
ATOM 5267 O OE2 . GLU B 2 642 ? 138.273 177.799 126.038 1.00 144.27 ? 642 GLU A OE2 1 
ATOM 5268 N N   . ARG B 2 643 ? 136.885 174.111 124.120 1.00 138.60 ? 643 ARG A N   1 
ATOM 5269 C CA  . ARG B 2 643 ? 137.257 174.530 122.775 1.00 140.01 ? 643 ARG A CA  1 
ATOM 5270 C C   . ARG B 2 643 ? 135.981 174.736 121.971 1.00 142.16 ? 643 ARG A C   1 
ATOM 5271 O O   . ARG B 2 643 ? 135.865 175.709 121.216 1.00 143.69 ? 643 ARG A O   1 
ATOM 5272 C CB  . ARG B 2 643 ? 138.182 173.532 122.081 1.00 140.80 ? 643 ARG A CB  1 
ATOM 5273 C CG  . ARG B 2 643 ? 139.663 173.823 122.278 1.00 140.23 ? 643 ARG A CG  1 
ATOM 5274 C CD  . ARG B 2 643 ? 139.997 175.269 121.942 1.00 140.15 ? 643 ARG A CD  1 
ATOM 5275 N NE  . ARG B 2 643 ? 140.078 176.111 123.130 1.00 139.65 ? 643 ARG A NE  1 
ATOM 5276 C CZ  . ARG B 2 643 ? 140.663 177.300 123.165 1.00 141.55 ? 643 ARG A CZ  1 
ATOM 5277 N NH1 . ARG B 2 643 ? 141.237 177.820 122.092 1.00 141.93 ? 643 ARG A NH1 1 
ATOM 5278 N NH2 . ARG B 2 643 ? 140.673 177.985 124.304 1.00 142.84 ? 643 ARG A NH2 1 
ATOM 5279 N N   . SER B 2 644 ? 135.010 173.833 122.122 1.00 147.98 ? 644 SER A N   1 
ATOM 5280 C CA  . SER B 2 644 ? 133.734 174.009 121.437 1.00 150.06 ? 644 SER A CA  1 
ATOM 5281 C C   . SER B 2 644 ? 133.038 175.286 121.890 1.00 147.21 ? 644 SER A C   1 
ATOM 5282 O O   . SER B 2 644 ? 132.522 176.051 121.065 1.00 145.81 ? 644 SER A O   1 
ATOM 5283 C CB  . SER B 2 644 ? 132.836 172.797 121.677 1.00 149.08 ? 644 SER A CB  1 
ATOM 5284 O OG  . SER B 2 644 ? 131.979 173.014 122.784 1.00 149.84 ? 644 SER A OG  1 
ATOM 5285 N N   . LEU B 2 645 ? 133.020 175.537 123.201 1.00 140.81 ? 645 LEU A N   1 
ATOM 5286 C CA  . LEU B 2 645 ? 132.383 176.748 123.711 1.00 140.28 ? 645 LEU A CA  1 
ATOM 5287 C C   . LEU B 2 645 ? 133.093 178.001 123.214 1.00 141.18 ? 645 LEU A C   1 
ATOM 5288 O O   . LEU B 2 645 ? 132.444 178.992 122.860 1.00 143.77 ? 645 LEU A O   1 
ATOM 5289 C CB  . LEU B 2 645 ? 132.340 176.724 125.239 1.00 140.91 ? 645 LEU A CB  1 
ATOM 5290 C CG  . LEU B 2 645 ? 131.129 176.073 125.917 1.00 142.13 ? 645 LEU A CG  1 
ATOM 5291 C CD1 . LEU B 2 645 ? 129.932 177.010 125.859 1.00 141.51 ? 645 LEU A CD1 1 
ATOM 5292 C CD2 . LEU B 2 645 ? 130.780 174.725 125.303 1.00 141.27 ? 645 LEU A CD2 1 
ATOM 5293 N N   . SER B 2 646 ? 134.427 177.979 123.183 1.00 143.78 ? 646 SER A N   1 
ATOM 5294 C CA  . SER B 2 646 ? 135.173 179.132 122.691 1.00 144.91 ? 646 SER A CA  1 
ATOM 5295 C C   . SER B 2 646 ? 134.941 179.354 121.204 1.00 145.22 ? 646 SER A C   1 
ATOM 5296 O O   . SER B 2 646 ? 134.915 180.502 120.746 1.00 143.60 ? 646 SER A O   1 
ATOM 5297 C CB  . SER B 2 646 ? 136.664 178.956 122.973 1.00 145.80 ? 646 SER A CB  1 
ATOM 5298 O OG  . SER B 2 646 ? 137.128 177.710 122.489 1.00 146.83 ? 646 SER A OG  1 
ATOM 5299 N N   . ALA B 2 647 ? 134.781 178.276 120.435 1.00 149.65 ? 647 ALA A N   1 
ATOM 5300 C CA  . ALA B 2 647 ? 134.463 178.414 119.021 1.00 150.51 ? 647 ALA A CA  1 
ATOM 5301 C C   . ALA B 2 647 ? 133.022 178.848 118.798 1.00 153.50 ? 647 ALA A C   1 
ATOM 5302 O O   . ALA B 2 647 ? 132.702 179.352 117.716 1.00 152.90 ? 647 ALA A O   1 
ATOM 5303 C CB  . ALA B 2 647 ? 134.730 177.098 118.290 1.00 149.56 ? 647 ALA A CB  1 
ATOM 5304 N N   . LYS B 2 648 ? 132.148 178.658 119.790 1.00 154.92 ? 648 LYS A N   1 
ATOM 5305 C CA  . LYS B 2 648 ? 130.762 179.095 119.648 1.00 152.67 ? 648 LYS A CA  1 
ATOM 5306 C C   . LYS B 2 648 ? 130.672 180.606 119.470 1.00 152.08 ? 648 LYS A C   1 
ATOM 5307 O O   . LYS B 2 648 ? 129.907 181.095 118.631 1.00 149.98 ? 648 LYS A O   1 
ATOM 5308 C CB  . LYS B 2 648 ? 129.943 178.648 120.858 1.00 149.51 ? 648 LYS A CB  1 
ATOM 5309 C CG  . LYS B 2 648 ? 128.519 179.179 120.873 1.00 147.31 ? 648 LYS A CG  1 
ATOM 5310 C CD  . LYS B 2 648 ? 127.846 178.927 122.212 1.00 149.25 ? 648 LYS A CD  1 
ATOM 5311 C CE  . LYS B 2 648 ? 127.488 177.460 122.383 1.00 149.15 ? 648 LYS A CE  1 
ATOM 5312 N NZ  . LYS B 2 648 ? 126.475 177.260 123.456 1.00 147.00 ? 648 LYS A NZ  1 
ATOM 5313 N N   . ASP B 2 649 ? 131.443 181.361 120.246 1.00 157.57 ? 649 ASP A N   1 
ATOM 5314 C CA  . ASP B 2 649 ? 131.428 182.816 120.139 1.00 155.33 ? 649 ASP A CA  1 
ATOM 5315 C C   . ASP B 2 649 ? 132.589 183.312 119.283 1.00 154.39 ? 649 ASP A C   1 
ATOM 5316 O O   . ASP B 2 649 ? 133.194 182.544 118.536 1.00 152.75 ? 649 ASP A O   1 
ATOM 5317 C CB  . ASP B 2 649 ? 131.483 183.461 121.525 1.00 155.28 ? 649 ASP A CB  1 
ATOM 5318 C CG  . ASP B 2 649 ? 132.896 183.579 122.059 1.00 158.15 ? 649 ASP A CG  1 
ATOM 5319 O OD1 . ASP B 2 649 ? 133.601 182.551 122.112 1.00 158.31 ? 649 ASP A OD1 1 
ATOM 5320 O OD2 . ASP B 2 649 ? 133.304 184.702 122.423 1.00 157.13 ? 649 ASP A OD2 1 
ATOM 5321 N N   . ASN B 2 657 ? 133.331 184.948 135.297 1.00 166.06 ? 657 ASN A N   1 
ATOM 5322 C CA  . ASN B 2 657 ? 133.104 184.323 133.999 1.00 166.82 ? 657 ASN A CA  1 
ATOM 5323 C C   . ASN B 2 657 ? 133.050 182.804 134.142 1.00 167.10 ? 657 ASN A C   1 
ATOM 5324 O O   . ASN B 2 657 ? 133.021 182.278 135.255 1.00 165.78 ? 657 ASN A O   1 
ATOM 5325 C CB  . ASN B 2 657 ? 134.199 184.730 133.010 1.00 165.26 ? 657 ASN A CB  1 
ATOM 5326 C CG  . ASN B 2 657 ? 133.701 184.789 131.579 1.00 164.78 ? 657 ASN A CG  1 
ATOM 5327 O OD1 . ASN B 2 657 ? 132.837 184.010 131.178 1.00 164.53 ? 657 ASN A OD1 1 
ATOM 5328 N ND2 . ASN B 2 657 ? 134.246 185.717 130.801 1.00 163.04 ? 657 ASN A ND2 1 
ATOM 5329 N N   . HIS B 2 658 ? 133.038 182.100 133.008 1.00 159.07 ? 658 HIS A N   1 
ATOM 5330 C CA  . HIS B 2 658 ? 132.954 180.645 133.019 1.00 156.29 ? 658 HIS A CA  1 
ATOM 5331 C C   . HIS B 2 658 ? 134.272 179.972 133.380 1.00 155.65 ? 658 HIS A C   1 
ATOM 5332 O O   . HIS B 2 658 ? 134.309 178.740 133.470 1.00 155.44 ? 658 HIS A O   1 
ATOM 5333 C CB  . HIS B 2 658 ? 132.525 180.175 131.628 1.00 153.41 ? 658 HIS A CB  1 
ATOM 5334 C CG  . HIS B 2 658 ? 133.210 180.895 130.509 1.00 155.00 ? 658 HIS A CG  1 
ATOM 5335 N ND1 . HIS B 2 658 ? 132.519 181.528 129.499 1.00 155.09 ? 658 HIS A ND1 1 
ATOM 5336 C CD2 . HIS B 2 658 ? 134.524 181.083 130.243 1.00 154.19 ? 658 HIS A CD2 1 
ATOM 5337 C CE1 . HIS B 2 658 ? 133.378 182.075 128.657 1.00 155.55 ? 658 HIS A CE1 1 
ATOM 5338 N NE2 . HIS B 2 658 ? 134.601 181.820 129.086 1.00 155.69 ? 658 HIS A NE2 1 
ATOM 5339 N N   . LEU B 2 659 ? 135.349 180.737 133.572 1.00 150.06 ? 659 LEU A N   1 
ATOM 5340 C CA  . LEU B 2 659 ? 136.617 180.133 133.970 1.00 152.00 ? 659 LEU A CA  1 
ATOM 5341 C C   . LEU B 2 659 ? 136.506 179.472 135.339 1.00 152.51 ? 659 LEU A C   1 
ATOM 5342 O O   . LEU B 2 659 ? 137.081 178.401 135.569 1.00 151.63 ? 659 LEU A O   1 
ATOM 5343 C CB  . LEU B 2 659 ? 137.740 181.176 133.958 1.00 150.96 ? 659 LEU A CB  1 
ATOM 5344 C CG  . LEU B 2 659 ? 137.872 182.261 135.034 1.00 149.65 ? 659 LEU A CG  1 
ATOM 5345 C CD1 . LEU B 2 659 ? 139.074 183.142 134.730 1.00 148.43 ? 659 LEU A CD1 1 
ATOM 5346 C CD2 . LEU B 2 659 ? 136.620 183.115 135.173 1.00 148.13 ? 659 LEU A CD2 1 
ATOM 5347 N N   . LYS B 2 660 ? 135.772 180.095 136.264 1.00 148.81 ? 660 LYS A N   1 
ATOM 5348 C CA  . LYS B 2 660 ? 135.534 179.467 137.560 1.00 150.87 ? 660 LYS A CA  1 
ATOM 5349 C C   . LYS B 2 660 ? 134.731 178.182 137.403 1.00 150.03 ? 660 LYS A C   1 
ATOM 5350 O O   . LYS B 2 660 ? 135.002 177.179 138.077 1.00 150.69 ? 660 LYS A O   1 
ATOM 5351 C CB  . LYS B 2 660 ? 134.817 180.444 138.490 1.00 148.85 ? 660 LYS A CB  1 
ATOM 5352 C CG  . LYS B 2 660 ? 135.175 180.285 139.958 1.00 149.00 ? 660 LYS A CG  1 
ATOM 5353 C CD  . LYS B 2 660 ? 136.616 180.693 140.218 1.00 148.03 ? 660 LYS A CD  1 
ATOM 5354 C CE  . LYS B 2 660 ? 136.950 180.633 141.700 1.00 146.87 ? 660 LYS A CE  1 
ATOM 5355 N NZ  . LYS B 2 660 ? 136.262 181.707 142.469 1.00 146.59 ? 660 LYS A NZ  1 
ATOM 5356 N N   . GLN B 2 661 ? 133.739 178.194 136.509 1.00 145.55 ? 661 GLN A N   1 
ATOM 5357 C CA  . GLN B 2 661 ? 132.967 176.986 136.242 1.00 146.32 ? 661 GLN A CA  1 
ATOM 5358 C C   . GLN B 2 661 ? 133.859 175.874 135.709 1.00 148.39 ? 661 GLN A C   1 
ATOM 5359 O O   . GLN B 2 661 ? 133.720 174.711 136.103 1.00 150.16 ? 661 GLN A O   1 
ATOM 5360 C CB  . GLN B 2 661 ? 131.870 177.293 135.222 1.00 144.48 ? 661 GLN A CB  1 
ATOM 5361 C CG  . GLN B 2 661 ? 131.093 178.565 135.508 1.00 145.85 ? 661 GLN A CG  1 
ATOM 5362 C CD  . GLN B 2 661 ? 130.476 178.570 136.890 1.00 149.08 ? 661 GLN A CD  1 
ATOM 5363 O OE1 . GLN B 2 661 ? 129.494 177.875 137.148 1.00 150.61 ? 661 GLN A OE1 1 
ATOM 5364 N NE2 . GLN B 2 661 ? 131.052 179.358 137.791 1.00 146.85 ? 661 GLN A NE2 1 
ATOM 5365 N N   . PHE B 2 662 ? 134.788 176.214 134.815 1.00 136.74 ? 662 PHE A N   1 
ATOM 5366 C CA  . PHE B 2 662 ? 135.675 175.195 134.265 1.00 134.83 ? 662 PHE A CA  1 
ATOM 5367 C C   . PHE B 2 662 ? 136.681 174.706 135.299 1.00 136.29 ? 662 PHE A C   1 
ATOM 5368 O O   . PHE B 2 662 ? 137.063 173.534 135.275 1.00 138.57 ? 662 PHE A O   1 
ATOM 5369 C CB  . PHE B 2 662 ? 136.383 175.729 133.024 1.00 132.75 ? 662 PHE A CB  1 
ATOM 5370 C CG  . PHE B 2 662 ? 135.683 175.381 131.747 1.00 133.46 ? 662 PHE A CG  1 
ATOM 5371 C CD1 . PHE B 2 662 ? 135.115 174.130 131.580 1.00 132.90 ? 662 PHE A CD1 1 
ATOM 5372 C CD2 . PHE B 2 662 ? 135.573 176.304 130.724 1.00 135.45 ? 662 PHE A CD2 1 
ATOM 5373 C CE1 . PHE B 2 662 ? 134.460 173.802 130.412 1.00 133.38 ? 662 PHE A CE1 1 
ATOM 5374 C CE2 . PHE B 2 662 ? 134.918 175.981 129.553 1.00 137.57 ? 662 PHE A CE2 1 
ATOM 5375 C CZ  . PHE B 2 662 ? 134.360 174.728 129.399 1.00 135.24 ? 662 PHE A CZ  1 
ATOM 5376 N N   . ARG B 2 663 ? 137.118 175.577 136.211 1.00 129.18 ? 663 ARG A N   1 
ATOM 5377 C CA  . ARG B 2 663 ? 137.953 175.116 137.317 1.00 130.12 ? 663 ARG A CA  1 
ATOM 5378 C C   . ARG B 2 663 ? 137.197 174.123 138.192 1.00 130.10 ? 663 ARG A C   1 
ATOM 5379 O O   . ARG B 2 663 ? 137.749 173.095 138.607 1.00 131.82 ? 663 ARG A O   1 
ATOM 5380 C CB  . ARG B 2 663 ? 138.435 176.308 138.144 1.00 125.77 ? 663 ARG A CB  1 
ATOM 5381 C CG  . ARG B 2 663 ? 138.967 175.936 139.521 1.00 128.74 ? 663 ARG A CG  1 
ATOM 5382 C CD  . ARG B 2 663 ? 140.477 176.109 139.613 1.00 128.83 ? 663 ARG A CD  1 
ATOM 5383 N NE  . ARG B 2 663 ? 141.078 175.144 140.527 1.00 129.51 ? 663 ARG A NE  1 
ATOM 5384 C CZ  . ARG B 2 663 ? 142.378 175.053 140.772 1.00 127.18 ? 663 ARG A CZ  1 
ATOM 5385 N NH1 . ARG B 2 663 ? 143.249 175.868 140.202 1.00 124.73 ? 663 ARG A NH1 1 
ATOM 5386 N NH2 . ARG B 2 663 ? 142.815 174.120 141.614 1.00 123.00 ? 663 ARG A NH2 1 
ATOM 5387 N N   . VAL B 2 664 ? 135.925 174.414 138.474 1.00 132.22 ? 664 VAL A N   1 
ATOM 5388 C CA  . VAL B 2 664 ? 135.099 173.481 139.237 1.00 133.74 ? 664 VAL A CA  1 
ATOM 5389 C C   . VAL B 2 664 ? 134.960 172.160 138.490 1.00 136.21 ? 664 VAL A C   1 
ATOM 5390 O O   . VAL B 2 664 ? 135.036 171.078 139.086 1.00 139.65 ? 664 VAL A O   1 
ATOM 5391 C CB  . VAL B 2 664 ? 133.727 174.110 139.540 1.00 136.07 ? 664 VAL A CB  1 
ATOM 5392 C CG1 . VAL B 2 664 ? 132.772 173.069 140.100 1.00 135.30 ? 664 VAL A CG1 1 
ATOM 5393 C CG2 . VAL B 2 664 ? 133.881 175.271 140.508 1.00 137.14 ? 664 VAL A CG2 1 
ATOM 5394 N N   . ALA B 2 665 ? 134.750 172.229 137.174 1.00 128.85 ? 665 ALA A N   1 
ATOM 5395 C CA  . ALA B 2 665 ? 134.637 171.013 136.373 1.00 129.52 ? 665 ALA A CA  1 
ATOM 5396 C C   . ALA B 2 665 ? 135.930 170.207 136.402 1.00 130.44 ? 665 ALA A C   1 
ATOM 5397 O O   . ALA B 2 665 ? 135.901 168.973 136.444 1.00 129.84 ? 665 ALA A O   1 
ATOM 5398 C CB  . ALA B 2 665 ? 134.257 171.367 134.935 1.00 125.28 ? 665 ALA A CB  1 
ATOM 5399 N N   . ALA B 2 666 ? 137.075 170.889 136.358 1.00 121.20 ? 666 ALA A N   1 
ATOM 5400 C CA  . ALA B 2 666 ? 138.358 170.198 136.434 1.00 118.44 ? 666 ALA A CA  1 
ATOM 5401 C C   . ALA B 2 666 ? 138.531 169.505 137.778 1.00 118.09 ? 666 ALA A C   1 
ATOM 5402 O O   . ALA B 2 666 ? 139.018 168.369 137.844 1.00 117.99 ? 666 ALA A O   1 
ATOM 5403 C CB  . ALA B 2 666 ? 139.497 171.185 136.187 1.00 120.30 ? 666 ALA A CB  1 
ATOM 5404 N N   . LEU B 2 667 ? 138.148 170.179 138.864 1.00 119.13 ? 667 LEU A N   1 
ATOM 5405 C CA  . LEU B 2 667 ? 138.200 169.537 140.175 1.00 121.49 ? 667 LEU A CA  1 
ATOM 5406 C C   . LEU B 2 667 ? 137.282 168.322 140.224 1.00 121.12 ? 667 LEU A C   1 
ATOM 5407 O O   . LEU B 2 667 ? 137.634 167.288 140.806 1.00 122.51 ? 667 LEU A O   1 
ATOM 5408 C CB  . LEU B 2 667 ? 137.833 170.538 141.269 1.00 122.69 ? 667 LEU A CB  1 
ATOM 5409 C CG  . LEU B 2 667 ? 138.996 171.111 142.083 1.00 124.45 ? 667 LEU A CG  1 
ATOM 5410 C CD1 . LEU B 2 667 ? 139.480 170.096 143.107 1.00 123.26 ? 667 LEU A CD1 1 
ATOM 5411 C CD2 . LEU B 2 667 ? 140.137 171.546 141.176 1.00 118.39 ? 667 LEU A CD2 1 
ATOM 5412 N N   . LEU B 2 668 ? 136.101 168.428 139.612 1.00 126.81 ? 668 LEU A N   1 
ATOM 5413 C CA  . LEU B 2 668 ? 135.185 167.293 139.560 1.00 127.36 ? 668 LEU A CA  1 
ATOM 5414 C C   . LEU B 2 668 ? 135.786 166.133 138.777 1.00 127.94 ? 668 LEU A C   1 
ATOM 5415 O O   . LEU B 2 668 ? 135.634 164.969 139.163 1.00 130.27 ? 668 LEU A O   1 
ATOM 5416 C CB  . LEU B 2 668 ? 133.852 167.721 138.945 1.00 125.24 ? 668 LEU A CB  1 
ATOM 5417 C CG  . LEU B 2 668 ? 132.728 168.154 139.890 1.00 127.14 ? 668 LEU A CG  1 
ATOM 5418 C CD1 . LEU B 2 668 ? 133.260 168.968 141.061 1.00 127.96 ? 668 LEU A CD1 1 
ATOM 5419 C CD2 . LEU B 2 668 ? 131.670 168.937 139.128 1.00 125.74 ? 668 LEU A CD2 1 
ATOM 5420 N N   . ALA B 2 669 ? 136.458 166.430 137.664 1.00 123.35 ? 669 ALA A N   1 
ATOM 5421 C CA  . ALA B 2 669 ? 137.098 165.379 136.879 1.00 125.64 ? 669 ALA A CA  1 
ATOM 5422 C C   . ALA B 2 669 ? 138.218 164.709 137.664 1.00 122.74 ? 669 ALA A C   1 
ATOM 5423 O O   . ALA B 2 669 ? 138.382 163.483 137.609 1.00 119.70 ? 669 ALA A O   1 
ATOM 5424 C CB  . ALA B 2 669 ? 137.631 165.953 135.567 1.00 125.23 ? 669 ALA A CB  1 
ATOM 5425 N N   . PHE B 2 670 ? 139.004 165.500 138.397 1.00 111.40 ? 670 PHE A N   1 
ATOM 5426 C CA  . PHE B 2 670 ? 140.041 164.924 139.247 1.00 106.83 ? 670 PHE A CA  1 
ATOM 5427 C C   . PHE B 2 670 ? 139.437 164.022 140.315 1.00 110.85 ? 670 PHE A C   1 
ATOM 5428 O O   . PHE B 2 670 ? 139.958 162.934 140.589 1.00 114.89 ? 670 PHE A O   1 
ATOM 5429 C CB  . PHE B 2 670 ? 140.871 166.032 139.891 1.00 108.25 ? 670 PHE A CB  1 
ATOM 5430 C CG  . PHE B 2 670 ? 142.206 166.243 139.242 1.00 109.94 ? 670 PHE A CG  1 
ATOM 5431 C CD1 . PHE B 2 670 ? 142.306 166.881 138.020 1.00 110.53 ? 670 PHE A CD1 1 
ATOM 5432 C CD2 . PHE B 2 670 ? 143.365 165.804 139.858 1.00 112.50 ? 670 PHE A CD2 1 
ATOM 5433 C CE1 . PHE B 2 670 ? 143.535 167.077 137.424 1.00 112.19 ? 670 PHE A CE1 1 
ATOM 5434 C CE2 . PHE B 2 670 ? 144.596 165.997 139.267 1.00 110.79 ? 670 PHE A CE2 1 
ATOM 5435 C CZ  . PHE B 2 670 ? 144.681 166.634 138.048 1.00 111.53 ? 670 PHE A CZ  1 
ATOM 5436 N N   . LEU B 2 671 ? 138.336 164.459 140.932 1.00 119.42 ? 671 LEU A N   1 
ATOM 5437 C CA  . LEU B 2 671 ? 137.678 163.634 141.941 1.00 118.22 ? 671 LEU A CA  1 
ATOM 5438 C C   . LEU B 2 671 ? 137.134 162.346 141.334 1.00 119.04 ? 671 LEU A C   1 
ATOM 5439 O O   . LEU B 2 671 ? 137.198 161.281 141.959 1.00 125.12 ? 671 LEU A O   1 
ATOM 5440 C CB  . LEU B 2 671 ? 136.559 164.426 142.617 1.00 120.59 ? 671 LEU A CB  1 
ATOM 5441 C CG  . LEU B 2 671 ? 136.880 164.970 144.011 1.00 125.11 ? 671 LEU A CG  1 
ATOM 5442 C CD1 . LEU B 2 671 ? 137.068 163.830 144.997 1.00 125.39 ? 671 LEU A CD1 1 
ATOM 5443 C CD2 . LEU B 2 671 ? 138.113 165.859 143.975 1.00 122.85 ? 671 LEU A CD2 1 
ATOM 5444 N N   . GLY B 2 672 ? 136.582 162.427 140.123 1.00 118.12 ? 672 GLY A N   1 
ATOM 5445 C CA  . GLY B 2 672 ? 136.107 161.226 139.456 1.00 121.65 ? 672 GLY A CA  1 
ATOM 5446 C C   . GLY B 2 672 ? 137.227 160.252 139.149 1.00 126.30 ? 672 GLY A C   1 
ATOM 5447 O O   . GLY B 2 672 ? 137.079 159.040 139.329 1.00 129.76 ? 672 GLY A O   1 
ATOM 5448 N N   . ALA B 2 673 ? 138.365 160.767 138.682 1.00 122.71 ? 673 ALA A N   1 
ATOM 5449 C CA  . ALA B 2 673 ? 139.519 159.903 138.456 1.00 117.60 ? 673 ALA A CA  1 
ATOM 5450 C C   . ALA B 2 673 ? 139.985 159.263 139.757 1.00 112.59 ? 673 ALA A C   1 
ATOM 5451 O O   . ALA B 2 673 ? 140.317 158.072 139.789 1.00 111.44 ? 673 ALA A O   1 
ATOM 5452 C CB  . ALA B 2 673 ? 140.653 160.698 137.812 1.00 118.76 ? 673 ALA A CB  1 
ATOM 5453 N N   . THR B 2 674 ? 140.005 160.038 140.843 1.00 111.74 ? 674 THR A N   1 
ATOM 5454 C CA  . THR B 2 674 ? 140.423 159.501 142.133 1.00 108.66 ? 674 THR A CA  1 
ATOM 5455 C C   . THR B 2 674 ? 139.487 158.396 142.605 1.00 109.29 ? 674 THR A C   1 
ATOM 5456 O O   . THR B 2 674 ? 139.941 157.358 143.101 1.00 113.71 ? 674 THR A O   1 
ATOM 5457 C CB  . THR B 2 674 ? 140.489 160.618 143.173 1.00 110.86 ? 674 THR A CB  1 
ATOM 5458 O OG1 . THR B 2 674 ? 141.080 161.784 142.587 1.00 118.77 ? 674 THR A OG1 1 
ATOM 5459 C CG2 . THR B 2 674 ? 141.320 160.181 144.367 1.00 113.24 ? 674 THR A CG2 1 
ATOM 5460 N N   . VAL B 2 675 ? 138.176 158.600 142.466 1.00 122.91 ? 675 VAL A N   1 
ATOM 5461 C CA  . VAL B 2 675 ? 137.235 157.581 142.918 1.00 124.30 ? 675 VAL A CA  1 
ATOM 5462 C C   . VAL B 2 675 ? 137.323 156.340 142.037 1.00 125.66 ? 675 VAL A C   1 
ATOM 5463 O O   . VAL B 2 675 ? 137.233 155.211 142.537 1.00 127.64 ? 675 VAL A O   1 
ATOM 5464 C CB  . VAL B 2 675 ? 135.803 158.153 142.994 1.00 126.28 ? 675 VAL A CB  1 
ATOM 5465 C CG1 . VAL B 2 675 ? 135.182 158.322 141.620 1.00 123.81 ? 675 VAL A CG1 1 
ATOM 5466 C CG2 . VAL B 2 675 ? 134.928 157.267 143.853 1.00 126.73 ? 675 VAL A CG2 1 
ATOM 5467 N N   . ALA B 2 676 ? 137.530 156.516 140.728 1.00 125.58 ? 676 ALA A N   1 
ATOM 5468 C CA  . ALA B 2 676 ? 137.704 155.363 139.852 1.00 124.02 ? 676 ALA A CA  1 
ATOM 5469 C C   . ALA B 2 676 ? 138.953 154.577 140.224 1.00 123.71 ? 676 ALA A C   1 
ATOM 5470 O O   . ALA B 2 676 ? 138.953 153.342 140.186 1.00 124.27 ? 676 ALA A O   1 
ATOM 5471 C CB  . ALA B 2 676 ? 137.766 155.813 138.393 1.00 124.32 ? 676 ALA A CB  1 
ATOM 5472 N N   . GLY B 2 677 ? 140.032 155.278 140.574 1.00 123.28 ? 677 GLY A N   1 
ATOM 5473 C CA  . GLY B 2 677 ? 141.240 154.592 140.999 1.00 120.98 ? 677 GLY A CA  1 
ATOM 5474 C C   . GLY B 2 677 ? 141.081 153.882 142.331 1.00 120.75 ? 677 GLY A C   1 
ATOM 5475 O O   . GLY B 2 677 ? 141.631 152.797 142.533 1.00 124.80 ? 677 GLY A O   1 
ATOM 5476 N N   . CYS B 2 678 ? 140.349 154.493 143.263 1.00 130.28 ? 678 CYS A N   1 
ATOM 5477 C CA  . CYS B 2 678 ? 140.189 153.912 144.593 1.00 131.62 ? 678 CYS A CA  1 
ATOM 5478 C C   . CYS B 2 678 ? 139.217 152.741 144.602 1.00 131.26 ? 678 CYS A C   1 
ATOM 5479 O O   . CYS B 2 678 ? 139.309 151.870 145.473 1.00 131.80 ? 678 CYS A O   1 
ATOM 5480 C CB  . CYS B 2 678 ? 139.721 154.983 145.578 1.00 132.47 ? 678 CYS A CB  1 
ATOM 5481 S SG  . CYS B 2 678 ? 141.040 155.684 146.585 1.00 139.08 ? 678 CYS A SG  1 
ATOM 5482 N N   . PHE B 2 679 ? 138.285 152.714 143.654 1.00 143.69 ? 679 PHE A N   1 
ATOM 5483 C CA  . PHE B 2 679 ? 137.264 151.670 143.583 1.00 144.53 ? 679 PHE A CA  1 
ATOM 5484 C C   . PHE B 2 679 ? 137.810 150.244 143.585 1.00 145.27 ? 679 PHE A C   1 
ATOM 5485 O O   . PHE B 2 679 ? 137.260 149.405 144.315 1.00 146.54 ? 679 PHE A O   1 
ATOM 5486 C CB  . PHE B 2 679 ? 136.421 151.981 142.342 1.00 147.84 ? 679 PHE A CB  1 
ATOM 5487 C CG  . PHE B 2 679 ? 135.231 151.099 142.145 1.00 149.96 ? 679 PHE A CG  1 
ATOM 5488 C CD1 . PHE B 2 679 ? 133.990 151.494 142.612 1.00 149.65 ? 679 PHE A CD1 1 
ATOM 5489 C CD2 . PHE B 2 679 ? 135.331 149.921 141.418 1.00 149.10 ? 679 PHE A CD2 1 
ATOM 5490 C CE1 . PHE B 2 679 ? 132.868 150.711 142.383 1.00 150.72 ? 679 PHE A CE1 1 
ATOM 5491 C CE2 . PHE B 2 679 ? 134.215 149.130 141.189 1.00 150.26 ? 679 PHE A CE2 1 
ATOM 5492 C CZ  . PHE B 2 679 ? 132.977 149.539 141.647 1.00 150.41 ? 679 PHE A CZ  1 
ATOM 5493 N N   . PRO B 2 680 ? 138.848 149.891 142.816 1.00 139.13 ? 680 PRO A N   1 
ATOM 5494 C CA  . PRO B 2 680 ? 139.337 148.501 142.864 1.00 138.56 ? 680 PRO A CA  1 
ATOM 5495 C C   . PRO B 2 680 ? 139.948 148.105 144.195 1.00 137.12 ? 680 PRO A C   1 
ATOM 5496 O O   . PRO B 2 680 ? 140.172 146.909 144.415 1.00 137.00 ? 680 PRO A O   1 
ATOM 5497 C CB  . PRO B 2 680 ? 140.383 148.434 141.742 1.00 136.82 ? 680 PRO A CB  1 
ATOM 5498 C CG  . PRO B 2 680 ? 140.500 149.765 141.175 1.00 137.20 ? 680 PRO A CG  1 
ATOM 5499 C CD  . PRO B 2 680 ? 139.480 150.673 141.740 1.00 137.94 ? 680 PRO A CD  1 
ATOM 5500 N N   . LEU B 2 681 ? 140.256 149.057 145.077 1.00 132.23 ? 681 LEU A N   1 
ATOM 5501 C CA  . LEU B 2 681 ? 140.833 148.692 146.367 1.00 131.47 ? 681 LEU A CA  1 
ATOM 5502 C C   . LEU B 2 681 ? 139.966 147.804 147.252 1.00 134.31 ? 681 LEU A C   1 
ATOM 5503 O O   . LEU B 2 681 ? 140.448 146.813 147.810 1.00 137.32 ? 681 LEU A O   1 
ATOM 5504 C CB  . LEU B 2 681 ? 141.282 149.943 147.121 1.00 130.71 ? 681 LEU A CB  1 
ATOM 5505 C CG  . LEU B 2 681 ? 142.473 150.682 146.511 1.00 129.95 ? 681 LEU A CG  1 
ATOM 5506 C CD1 . LEU B 2 681 ? 142.423 152.160 146.854 1.00 134.16 ? 681 LEU A CD1 1 
ATOM 5507 C CD2 . LEU B 2 681 ? 143.780 150.065 146.970 1.00 129.37 ? 681 LEU A CD2 1 
ATOM 5508 N N   . PHE B 2 682 ? 138.680 148.140 147.391 1.00 154.00 ? 682 PHE A N   1 
ATOM 5509 C CA  . PHE B 2 682 ? 137.786 147.277 148.163 1.00 154.28 ? 682 PHE A CA  1 
ATOM 5510 C C   . PHE B 2 682 ? 137.345 146.012 147.415 1.00 154.12 ? 682 PHE A C   1 
ATOM 5511 O O   . PHE B 2 682 ? 137.146 144.948 148.011 1.00 152.40 ? 682 PHE A O   1 
ATOM 5512 C CB  . PHE B 2 682 ? 136.505 148.020 148.541 1.00 155.66 ? 682 PHE A CB  1 
ATOM 5513 C CG  . PHE B 2 682 ? 136.724 149.183 149.470 1.00 158.67 ? 682 PHE A CG  1 
ATOM 5514 C CD1 . PHE B 2 682 ? 136.828 148.983 150.835 1.00 154.97 ? 682 PHE A CD1 1 
ATOM 5515 C CD2 . PHE B 2 682 ? 136.774 150.481 148.978 1.00 160.03 ? 682 PHE A CD2 1 
ATOM 5516 C CE1 . PHE B 2 682 ? 137.013 150.044 151.694 1.00 154.28 ? 682 PHE A CE1 1 
ATOM 5517 C CE2 . PHE B 2 682 ? 136.946 151.549 149.844 1.00 158.31 ? 682 PHE A CE2 1 
ATOM 5518 C CZ  . PHE B 2 682 ? 137.073 151.328 151.199 1.00 156.64 ? 682 PHE A CZ  1 
ATOM 5519 N N   . HIS B 2 683 ? 137.219 146.117 146.096 1.00 156.71 ? 683 HIS A N   1 
ATOM 5520 C CA  . HIS B 2 683 ? 136.940 144.933 145.302 1.00 156.71 ? 683 HIS A CA  1 
ATOM 5521 C C   . HIS B 2 683 ? 138.210 144.092 145.381 1.00 157.12 ? 683 HIS A C   1 
ATOM 5522 O O   . HIS B 2 683 ? 139.313 144.600 145.600 1.00 159.15 ? 683 HIS A O   1 
ATOM 5523 C CB  . HIS B 2 683 ? 136.549 145.178 143.846 1.00 156.09 ? 683 HIS A CB  1 
ATOM 5524 C CG  . HIS B 2 683 ? 135.082 145.390 143.644 1.00 159.26 ? 683 HIS A CG  1 
ATOM 5525 N ND1 . HIS B 2 683 ? 134.443 145.089 142.461 1.00 159.46 ? 683 HIS A ND1 1 
ATOM 5526 C CD2 . HIS B 2 683 ? 134.127 145.871 144.475 1.00 159.52 ? 683 HIS A CD2 1 
ATOM 5527 C CE1 . HIS B 2 683 ? 133.158 145.376 142.571 1.00 159.17 ? 683 HIS A CE1 1 
ATOM 5528 N NE2 . HIS B 2 683 ? 132.941 145.852 143.784 1.00 159.42 ? 683 HIS A NE2 1 
ATOM 5529 N N   . ARG B 2 684 ? 138.044 142.786 145.212 1.00 165.58 ? 684 ARG A N   1 
ATOM 5530 C CA  . ARG B 2 684 ? 139.129 141.835 145.405 1.00 168.83 ? 684 ARG A CA  1 
ATOM 5531 C C   . ARG B 2 684 ? 139.490 141.186 144.077 1.00 170.19 ? 684 ARG A C   1 
ATOM 5532 O O   . ARG B 2 684 ? 138.607 140.713 143.353 1.00 167.87 ? 684 ARG A O   1 
ATOM 5533 C CB  . ARG B 2 684 ? 138.745 140.758 146.427 1.00 168.09 ? 684 ARG A CB  1 
ATOM 5534 C CG  . ARG B 2 684 ? 137.974 141.260 147.645 1.00 167.95 ? 684 ARG A CG  1 
ATOM 5535 C CD  . ARG B 2 684 ? 138.674 142.413 148.353 1.00 168.84 ? 684 ARG A CD  1 
ATOM 5536 N NE  . ARG B 2 684 ? 140.104 142.188 148.516 1.00 170.91 ? 684 ARG A NE  1 
ATOM 5537 C CZ  . ARG B 2 684 ? 141.037 143.088 148.238 1.00 170.25 ? 684 ARG A CZ  1 
ATOM 5538 N NH1 . ARG B 2 684 ? 140.723 144.291 147.784 1.00 169.98 ? 684 ARG A NH1 1 
ATOM 5539 N NH2 . ARG B 2 684 ? 142.316 142.775 148.420 1.00 169.64 ? 684 ARG A NH2 1 
ATOM 5540 N N   . GLY B 2 685 ? 140.779 141.170 143.762 1.00 171.97 ? 685 GLY A N   1 
ATOM 5541 C CA  . GLY B 2 685 ? 141.292 140.394 142.658 1.00 170.49 ? 685 GLY A CA  1 
ATOM 5542 C C   . GLY B 2 685 ? 141.570 141.127 141.365 1.00 169.41 ? 685 GLY A C   1 
ATOM 5543 O O   . GLY B 2 685 ? 141.479 140.509 140.298 1.00 170.94 ? 685 GLY A O   1 
ATOM 5544 N N   . GLU B 2 686 ? 141.905 142.415 141.414 1.00 151.54 ? 686 GLU A N   1 
ATOM 5545 C CA  . GLU B 2 686 ? 142.287 143.138 140.206 1.00 152.79 ? 686 GLU A CA  1 
ATOM 5546 C C   . GLU B 2 686 ? 143.712 143.663 140.257 1.00 152.79 ? 686 GLU A C   1 
ATOM 5547 O O   . GLU B 2 686 ? 144.500 143.387 139.345 1.00 154.64 ? 686 GLU A O   1 
ATOM 5548 C CB  . GLU B 2 686 ? 141.317 144.298 139.941 1.00 151.61 ? 686 GLU A CB  1 
ATOM 5549 C CG  . GLU B 2 686 ? 140.735 144.933 141.183 1.00 151.68 ? 686 GLU A CG  1 
ATOM 5550 C CD  . GLU B 2 686 ? 139.282 144.568 141.387 1.00 155.78 ? 686 GLU A CD  1 
ATOM 5551 O OE1 . GLU B 2 686 ? 138.976 143.362 141.494 1.00 158.80 ? 686 GLU A OE1 1 
ATOM 5552 O OE2 . GLU B 2 686 ? 138.442 145.490 141.416 1.00 154.05 ? 686 GLU A OE2 1 
ATOM 5553 N N   . TYR B 2 687 ? 144.072 144.416 141.299 1.00 124.46 ? 687 TYR A N   1 
ATOM 5554 C CA  . TYR B 2 687 ? 145.413 144.983 141.370 1.00 122.83 ? 687 TYR A CA  1 
ATOM 5555 C C   . TYR B 2 687 ? 146.485 143.926 141.591 1.00 125.97 ? 687 TYR A C   1 
ATOM 5556 O O   . TYR B 2 687 ? 147.658 144.187 141.309 1.00 128.61 ? 687 TYR A O   1 
ATOM 5557 C CB  . TYR B 2 687 ? 145.486 146.034 142.477 1.00 116.96 ? 687 TYR A CB  1 
ATOM 5558 C CG  . TYR B 2 687 ? 144.941 147.384 142.074 1.00 119.47 ? 687 TYR A CG  1 
ATOM 5559 C CD1 . TYR B 2 687 ? 144.691 147.683 140.742 1.00 118.64 ? 687 TYR A CD1 1 
ATOM 5560 C CD2 . TYR B 2 687 ? 144.685 148.363 143.023 1.00 124.98 ? 687 TYR A CD2 1 
ATOM 5561 C CE1 . TYR B 2 687 ? 144.198 148.915 140.368 1.00 121.47 ? 687 TYR A CE1 1 
ATOM 5562 C CE2 . TYR B 2 687 ? 144.191 149.598 142.659 1.00 124.13 ? 687 TYR A CE2 1 
ATOM 5563 C CZ  . TYR B 2 687 ? 143.950 149.868 141.331 1.00 125.31 ? 687 TYR A CZ  1 
ATOM 5564 O OH  . TYR B 2 687 ? 143.458 151.098 140.965 1.00 125.65 ? 687 TYR A OH  1 
ATOM 5565 N N   . SER B 2 688 ? 146.115 142.748 142.082 1.00 118.36 ? 688 SER A N   1 
ATOM 5566 C CA  . SER B 2 688 ? 147.072 141.680 142.334 1.00 113.33 ? 688 SER A CA  1 
ATOM 5567 C C   . SER B 2 688 ? 147.172 140.687 141.185 1.00 114.04 ? 688 SER A C   1 
ATOM 5568 O O   . SER B 2 688 ? 147.876 139.681 141.316 1.00 118.47 ? 688 SER A O   1 
ATOM 5569 C CB  . SER B 2 688 ? 146.702 140.942 143.623 1.00 116.56 ? 688 SER A CB  1 
ATOM 5570 O OG  . SER B 2 688 ? 146.177 141.839 144.586 1.00 115.25 ? 688 SER A OG  1 
ATOM 5571 N N   . ALA B 2 689 ? 146.483 140.937 140.071 1.00 106.29 ? 689 ALA A N   1 
ATOM 5572 C CA  . ALA B 2 689 ? 146.500 139.990 138.961 1.00 105.95 ? 689 ALA A CA  1 
ATOM 5573 C C   . ALA B 2 689 ? 147.875 139.908 138.311 1.00 106.30 ? 689 ALA A C   1 
ATOM 5574 O O   . ALA B 2 689 ? 148.332 138.817 137.951 1.00 106.92 ? 689 ALA A O   1 
ATOM 5575 C CB  . ALA B 2 689 ? 145.442 140.376 137.929 1.00 107.61 ? 689 ALA A CB  1 
ATOM 5576 N N   . SER B 2 690 ? 148.548 141.042 138.150 1.00 99.69  ? 690 SER A N   1 
ATOM 5577 C CA  . SER B 2 690 ? 149.808 141.102 137.429 1.00 95.81  ? 690 SER A CA  1 
ATOM 5578 C C   . SER B 2 690 ? 150.829 141.912 138.211 1.00 92.67  ? 690 SER A C   1 
ATOM 5579 O O   . SER B 2 690 ? 150.462 142.813 138.970 1.00 99.53  ? 690 SER A O   1 
ATOM 5580 C CB  . SER B 2 690 ? 149.606 141.728 136.040 1.00 101.22 ? 690 SER A CB  1 
ATOM 5581 O OG  . SER B 2 690 ? 150.834 142.145 135.471 1.00 105.57 ? 690 SER A OG  1 
ATOM 5582 N N   . PRO B 2 691 ? 152.120 141.608 138.051 1.00 76.48  ? 691 PRO A N   1 
ATOM 5583 C CA  . PRO B 2 691 ? 153.150 142.446 138.683 1.00 84.01  ? 691 PRO A CA  1 
ATOM 5584 C C   . PRO B 2 691 ? 153.167 143.866 138.162 1.00 93.78  ? 691 PRO A C   1 
ATOM 5585 O O   . PRO B 2 691 ? 153.699 144.753 138.840 1.00 98.28  ? 691 PRO A O   1 
ATOM 5586 C CB  . PRO B 2 691 ? 154.453 141.709 138.351 1.00 76.57  ? 691 PRO A CB  1 
ATOM 5587 C CG  . PRO B 2 691 ? 154.136 140.919 137.137 1.00 84.19  ? 691 PRO A CG  1 
ATOM 5588 C CD  . PRO B 2 691 ? 152.713 140.491 137.302 1.00 81.54  ? 691 PRO A CD  1 
ATOM 5589 N N   . LEU B 2 692 ? 152.568 144.104 136.992 1.00 84.80  ? 692 LEU A N   1 
ATOM 5590 C CA  . LEU B 2 692 ? 152.443 145.479 136.452 1.00 76.55  ? 692 LEU A CA  1 
ATOM 5591 C C   . LEU B 2 692 ? 151.353 146.214 137.248 1.00 80.74  ? 692 LEU A C   1 
ATOM 5592 O O   . LEU B 2 692 ? 151.251 147.424 137.083 1.00 89.87  ? 692 LEU A O   1 
ATOM 5593 C CB  . LEU B 2 692 ? 152.140 145.404 134.957 1.00 76.52  ? 692 LEU A CB  1 
ATOM 5594 C CG  . LEU B 2 692 ? 153.159 144.638 134.106 1.00 82.38  ? 692 LEU A CG  1 
ATOM 5595 C CD1 . LEU B 2 692 ? 152.803 144.692 132.635 1.00 86.48  ? 692 LEU A CD1 1 
ATOM 5596 C CD2 . LEU B 2 692 ? 154.567 145.160 134.312 1.00 87.27  ? 692 LEU A CD2 1 
ATOM 5597 N N   . CYS B 2 693 ? 150.597 145.531 138.114 1.00 88.85  ? 693 CYS A N   1 
ATOM 5598 C CA  . CYS B 2 693 ? 149.554 146.137 138.936 1.00 91.48  ? 693 CYS A CA  1 
ATOM 5599 C C   . CYS B 2 693 ? 148.473 146.788 138.082 1.00 96.77  ? 693 CYS A C   1 
ATOM 5600 O O   . CYS B 2 693 ? 147.864 147.782 138.481 1.00 103.60 ? 693 CYS A O   1 
ATOM 5601 C CB  . CYS B 2 693 ? 150.145 147.149 139.920 1.00 93.57  ? 693 CYS A CB  1 
ATOM 5602 S SG  . CYS B 2 693 ? 151.493 146.489 140.918 1.00 101.56 ? 693 CYS A SG  1 
ATOM 5603 N N   . LEU B 2 694 ? 148.226 146.240 136.926 1.00 100.71 ? 694 LEU A N   1 
ATOM 5604 C CA  . LEU B 2 694 ? 147.214 146.827 136.070 1.00 99.58  ? 694 LEU A CA  1 
ATOM 5605 C C   . LEU B 2 694 ? 145.951 145.976 136.075 1.00 106.32 ? 694 LEU A C   1 
ATOM 5606 O O   . LEU B 2 694 ? 146.014 144.757 136.260 1.00 106.70 ? 694 LEU A O   1 
ATOM 5607 C CB  . LEU B 2 694 ? 147.734 146.961 134.636 1.00 100.51 ? 694 LEU A CB  1 
ATOM 5608 C CG  . LEU B 2 694 ? 148.580 148.203 134.364 1.00 91.77  ? 694 LEU A CG  1 
ATOM 5609 C CD1 . LEU B 2 694 ? 148.882 148.330 132.882 1.00 96.66  ? 694 LEU A CD1 1 
ATOM 5610 C CD2 . LEU B 2 694 ? 147.876 149.442 134.881 1.00 89.51  ? 694 LEU A CD2 1 
ATOM 5611 N N   . PRO B 2 695 ? 144.786 146.591 135.876 1.00 118.11 ? 695 PRO A N   1 
ATOM 5612 C CA  . PRO B 2 695 ? 143.537 145.819 135.878 1.00 114.92 ? 695 PRO A CA  1 
ATOM 5613 C C   . PRO B 2 695 ? 143.256 145.148 134.543 1.00 116.33 ? 695 PRO A C   1 
ATOM 5614 O O   . PRO B 2 695 ? 142.125 144.725 134.287 1.00 116.77 ? 695 PRO A O   1 
ATOM 5615 C CB  . PRO B 2 695 ? 142.466 146.869 136.212 1.00 114.92 ? 695 PRO A CB  1 
ATOM 5616 C CG  . PRO B 2 695 ? 143.183 148.195 136.317 1.00 112.73 ? 695 PRO A CG  1 
ATOM 5617 C CD  . PRO B 2 695 ? 144.542 148.033 135.734 1.00 114.08 ? 695 PRO A CD  1 
ATOM 5618 N N   . PHE B 2 696 ? 144.272 145.039 133.683 1.00 128.65 ? 696 PHE A N   1 
ATOM 5619 C CA  . PHE B 2 696 ? 144.138 144.437 132.358 1.00 126.62 ? 696 PHE A CA  1 
ATOM 5620 C C   . PHE B 2 696 ? 145.157 143.309 132.237 1.00 129.96 ? 696 PHE A C   1 
ATOM 5621 O O   . PHE B 2 696 ? 146.175 143.447 131.541 1.00 125.43 ? 696 PHE A O   1 
ATOM 5622 C CB  . PHE B 2 696 ? 144.336 145.475 131.255 1.00 121.74 ? 696 PHE A CB  1 
ATOM 5623 C CG  . PHE B 2 696 ? 143.837 146.844 131.615 1.00 127.00 ? 696 PHE A CG  1 
ATOM 5624 C CD1 . PHE B 2 696 ? 142.497 147.058 131.891 1.00 129.69 ? 696 PHE A CD1 1 
ATOM 5625 C CD2 . PHE B 2 696 ? 144.708 147.917 131.679 1.00 127.12 ? 696 PHE A CD2 1 
ATOM 5626 C CE1 . PHE B 2 696 ? 142.035 148.317 132.223 1.00 129.71 ? 696 PHE A CE1 1 
ATOM 5627 C CE2 . PHE B 2 696 ? 144.252 149.179 132.010 1.00 129.33 ? 696 PHE A CE2 1 
ATOM 5628 C CZ  . PHE B 2 696 ? 142.915 149.379 132.282 1.00 129.71 ? 696 PHE A CZ  1 
ATOM 5629 N N   . PRO B 2 697 ? 144.915 142.173 132.899 1.00 156.75 ? 697 PRO A N   1 
ATOM 5630 C CA  . PRO B 2 697 ? 145.884 141.073 132.855 1.00 155.13 ? 697 PRO A CA  1 
ATOM 5631 C C   . PRO B 2 697 ? 145.639 140.121 131.697 1.00 155.99 ? 697 PRO A C   1 
ATOM 5632 O O   . PRO B 2 697 ? 144.722 140.324 130.895 1.00 154.74 ? 697 PRO A O   1 
ATOM 5633 C CB  . PRO B 2 697 ? 145.664 140.379 134.202 1.00 152.72 ? 697 PRO A CB  1 
ATOM 5634 C CG  . PRO B 2 697 ? 144.192 140.571 134.461 1.00 153.33 ? 697 PRO A CG  1 
ATOM 5635 C CD  . PRO B 2 697 ? 143.755 141.840 133.745 1.00 154.71 ? 697 PRO A CD  1 
ATOM 5636 N N   . THR B 2 698 ? 146.458 139.078 131.604 1.00 170.90 ? 698 THR A N   1 
ATOM 5637 C CA  . THR B 2 698 ? 146.253 138.050 130.598 1.00 171.84 ? 698 THR A CA  1 
ATOM 5638 C C   . THR B 2 698 ? 145.070 137.161 130.974 1.00 171.78 ? 698 THR A C   1 
ATOM 5639 O O   . THR B 2 698 ? 144.688 137.045 132.142 1.00 170.29 ? 698 THR A O   1 
ATOM 5640 C CB  . THR B 2 698 ? 147.511 137.198 130.430 1.00 170.06 ? 698 THR A CB  1 
ATOM 5641 O OG1 . THR B 2 698 ? 147.283 136.198 129.429 1.00 172.02 ? 698 THR A OG1 1 
ATOM 5642 C CG2 . THR B 2 698 ? 147.876 136.521 131.743 1.00 168.19 ? 698 THR A CG2 1 
ATOM 5643 N N   . GLY B 2 699 ? 144.487 136.530 129.958 1.00 192.28 ? 699 GLY A N   1 
ATOM 5644 C CA  . GLY B 2 699 ? 143.363 135.649 130.196 1.00 191.83 ? 699 GLY A CA  1 
ATOM 5645 C C   . GLY B 2 699 ? 142.120 136.417 130.618 1.00 193.41 ? 699 GLY A C   1 
ATOM 5646 O O   . GLY B 2 699 ? 142.006 137.634 130.446 1.00 193.35 ? 699 GLY A O   1 
ATOM 5647 N N   . GLU B 2 700 ? 141.172 135.674 131.183 1.00 205.79 ? 700 GLU A N   1 
ATOM 5648 C CA  . GLU B 2 700 ? 139.944 136.282 131.675 1.00 205.31 ? 700 GLU A CA  1 
ATOM 5649 C C   . GLU B 2 700 ? 140.246 137.170 132.876 1.00 206.09 ? 700 GLU A C   1 
ATOM 5650 O O   . GLU B 2 700 ? 140.947 136.759 133.806 1.00 205.90 ? 700 GLU A O   1 
ATOM 5651 C CB  . GLU B 2 700 ? 138.931 135.203 132.052 1.00 204.46 ? 700 GLU A CB  1 
ATOM 5652 C CG  . GLU B 2 700 ? 137.652 135.739 132.676 1.00 204.49 ? 700 GLU A CG  1 
ATOM 5653 C CD  . GLU B 2 700 ? 137.654 135.643 134.190 1.00 205.79 ? 700 GLU A CD  1 
ATOM 5654 O OE1 . GLU B 2 700 ? 138.682 135.218 134.758 1.00 205.88 ? 700 GLU A OE1 1 
ATOM 5655 O OE2 . GLU B 2 700 ? 136.629 135.993 134.811 1.00 206.12 ? 700 GLU A OE2 1 
ATOM 5656 N N   . THR B 2 701 ? 139.719 138.385 132.853 1.00 204.63 ? 701 THR A N   1 
ATOM 5657 C CA  . THR B 2 701 ? 139.921 139.306 133.964 1.00 205.40 ? 701 THR A CA  1 
ATOM 5658 C C   . THR B 2 701 ? 139.061 138.879 135.149 1.00 205.85 ? 701 THR A C   1 
ATOM 5659 O O   . THR B 2 701 ? 137.853 138.683 134.987 1.00 205.96 ? 701 THR A O   1 
ATOM 5660 C CB  . THR B 2 701 ? 139.575 140.734 133.553 1.00 204.78 ? 701 THR A CB  1 
ATOM 5661 O OG1 . THR B 2 701 ? 138.163 140.939 133.678 1.00 205.19 ? 701 THR A OG1 1 
ATOM 5662 C CG2 . THR B 2 701 ? 139.992 140.987 132.112 1.00 202.08 ? 701 THR A CG2 1 
ATOM 5663 N N   . PRO B 2 702 ? 139.646 138.708 136.339 1.00 201.83 ? 702 PRO A N   1 
ATOM 5664 C CA  . PRO B 2 702 ? 138.835 138.274 137.492 1.00 200.50 ? 702 PRO A CA  1 
ATOM 5665 C C   . PRO B 2 702 ? 137.687 139.215 137.809 1.00 199.48 ? 702 PRO A C   1 
ATOM 5666 O O   . PRO B 2 702 ? 136.597 138.757 138.175 1.00 198.74 ? 702 PRO A O   1 
ATOM 5667 C CB  . PRO B 2 702 ? 139.858 138.216 138.636 1.00 199.36 ? 702 PRO A CB  1 
ATOM 5668 C CG  . PRO B 2 702 ? 141.192 138.115 137.963 1.00 198.79 ? 702 PRO A CG  1 
ATOM 5669 C CD  . PRO B 2 702 ? 141.064 138.887 136.689 1.00 199.30 ? 702 PRO A CD  1 
ATOM 5670 N N   . SER B 2 703 ? 137.898 140.522 137.678 1.00 190.27 ? 703 SER A N   1 
ATOM 5671 C CA  . SER B 2 703 ? 136.847 141.519 137.858 1.00 190.83 ? 703 SER A CA  1 
ATOM 5672 C C   . SER B 2 703 ? 136.452 142.020 136.472 1.00 190.22 ? 703 SER A C   1 
ATOM 5673 O O   . SER B 2 703 ? 136.946 143.040 135.991 1.00 188.09 ? 703 SER A O   1 
ATOM 5674 C CB  . SER B 2 703 ? 137.318 142.657 138.761 1.00 189.29 ? 703 SER A CB  1 
ATOM 5675 O OG  . SER B 2 703 ? 138.664 143.000 138.485 1.00 189.04 ? 703 SER A OG  1 
ATOM 5676 N N   . LEU B 2 704 ? 135.547 141.283 135.825 1.00 184.16 ? 704 LEU A N   1 
ATOM 5677 C CA  . LEU B 2 704 ? 135.120 141.650 134.479 1.00 182.23 ? 704 LEU A CA  1 
ATOM 5678 C C   . LEU B 2 704 ? 134.414 142.999 134.469 1.00 181.50 ? 704 LEU A C   1 
ATOM 5679 O O   . LEU B 2 704 ? 134.642 143.821 133.573 1.00 181.87 ? 704 LEU A O   1 
ATOM 5680 C CB  . LEU B 2 704 ? 134.211 140.565 133.903 1.00 180.93 ? 704 LEU A CB  1 
ATOM 5681 C CG  . LEU B 2 704 ? 134.872 139.226 133.568 1.00 182.04 ? 704 LEU A CG  1 
ATOM 5682 C CD1 . LEU B 2 704 ? 133.831 138.122 133.477 1.00 180.68 ? 704 LEU A CD1 1 
ATOM 5683 C CD2 . LEU B 2 704 ? 135.662 139.329 132.274 1.00 181.06 ? 704 LEU A CD2 1 
ATOM 5684 N N   . GLY B 2 705 ? 133.559 143.245 135.465 1.00 173.02 ? 705 GLY A N   1 
ATOM 5685 C CA  . GLY B 2 705 ? 132.757 144.457 135.461 1.00 172.76 ? 705 GLY A CA  1 
ATOM 5686 C C   . GLY B 2 705 ? 133.591 145.723 135.490 1.00 173.19 ? 705 GLY A C   1 
ATOM 5687 O O   . GLY B 2 705 ? 133.328 146.666 134.741 1.00 174.57 ? 705 GLY A O   1 
ATOM 5688 N N   . PHE B 2 706 ? 134.610 145.761 136.351 1.00 155.67 ? 706 PHE A N   1 
ATOM 5689 C CA  . PHE B 2 706 ? 135.440 146.956 136.457 1.00 154.63 ? 706 PHE A CA  1 
ATOM 5690 C C   . PHE B 2 706 ? 136.141 147.257 135.138 1.00 153.60 ? 706 PHE A C   1 
ATOM 5691 O O   . PHE B 2 706 ? 136.127 148.398 134.658 1.00 156.40 ? 706 PHE A O   1 
ATOM 5692 C CB  . PHE B 2 706 ? 136.460 146.788 137.582 1.00 152.55 ? 706 PHE A CB  1 
ATOM 5693 C CG  . PHE B 2 706 ? 137.374 147.965 137.747 1.00 151.97 ? 706 PHE A CG  1 
ATOM 5694 C CD1 . PHE B 2 706 ? 136.957 149.088 138.438 1.00 153.27 ? 706 PHE A CD1 1 
ATOM 5695 C CD2 . PHE B 2 706 ? 138.647 147.952 137.205 1.00 152.26 ? 706 PHE A CD2 1 
ATOM 5696 C CE1 . PHE B 2 706 ? 137.793 150.175 138.589 1.00 153.62 ? 706 PHE A CE1 1 
ATOM 5697 C CE2 . PHE B 2 706 ? 139.487 149.036 137.352 1.00 154.96 ? 706 PHE A CE2 1 
ATOM 5698 C CZ  . PHE B 2 706 ? 139.059 150.149 138.044 1.00 154.18 ? 706 PHE A CZ  1 
ATOM 5699 N N   . THR B 2 707 ? 136.757 146.239 134.534 1.00 154.87 ? 707 THR A N   1 
ATOM 5700 C CA  . THR B 2 707 ? 137.480 146.449 133.285 1.00 156.56 ? 707 THR A CA  1 
ATOM 5701 C C   . THR B 2 707 ? 136.542 146.876 132.165 1.00 157.39 ? 707 THR A C   1 
ATOM 5702 O O   . THR B 2 707 ? 136.849 147.814 131.414 1.00 155.08 ? 707 THR A O   1 
ATOM 5703 C CB  . THR B 2 707 ? 138.229 145.177 132.891 1.00 157.82 ? 707 THR A CB  1 
ATOM 5704 O OG1 . THR B 2 707 ? 137.298 144.208 132.395 1.00 159.81 ? 707 THR A OG1 1 
ATOM 5705 C CG2 . THR B 2 707 ? 138.956 144.600 134.089 1.00 158.73 ? 707 THR A CG2 1 
ATOM 5706 N N   . VAL B 2 708 ? 135.395 146.202 132.034 1.00 158.72 ? 708 VAL A N   1 
ATOM 5707 C CA  . VAL B 2 708 ? 134.490 146.535 130.940 1.00 157.48 ? 708 VAL A CA  1 
ATOM 5708 C C   . VAL B 2 708 ? 133.921 147.934 131.130 1.00 156.98 ? 708 VAL A C   1 
ATOM 5709 O O   . VAL B 2 708 ? 133.776 148.686 130.164 1.00 157.90 ? 708 VAL A O   1 
ATOM 5710 C CB  . VAL B 2 708 ? 133.381 145.475 130.781 1.00 155.91 ? 708 VAL A CB  1 
ATOM 5711 C CG1 . VAL B 2 708 ? 133.987 144.108 130.492 1.00 156.40 ? 708 VAL A CG1 1 
ATOM 5712 C CG2 . VAL B 2 708 ? 132.467 145.428 131.993 1.00 156.69 ? 708 VAL A CG2 1 
ATOM 5713 N N   . THR B 2 709 ? 133.626 148.325 132.373 1.00 156.58 ? 709 THR A N   1 
ATOM 5714 C CA  . THR B 2 709 ? 133.156 149.684 132.615 1.00 157.16 ? 709 THR A CA  1 
ATOM 5715 C C   . THR B 2 709 ? 134.226 150.704 132.248 1.00 158.73 ? 709 THR A C   1 
ATOM 5716 O O   . THR B 2 709 ? 133.950 151.687 131.548 1.00 157.54 ? 709 THR A O   1 
ATOM 5717 C CB  . THR B 2 709 ? 132.738 149.846 134.076 1.00 155.67 ? 709 THR A CB  1 
ATOM 5718 O OG1 . THR B 2 709 ? 133.700 149.208 134.924 1.00 157.56 ? 709 THR A OG1 1 
ATOM 5719 C CG2 . THR B 2 709 ? 131.372 149.225 134.309 1.00 156.72 ? 709 THR A CG2 1 
ATOM 5720 N N   . LEU B 2 710 ? 135.458 150.492 132.719 1.00 153.02 ? 710 LEU A N   1 
ATOM 5721 C CA  . LEU B 2 710 ? 136.517 151.458 132.454 1.00 150.16 ? 710 LEU A CA  1 
ATOM 5722 C C   . LEU B 2 710 ? 136.717 151.647 130.957 1.00 147.43 ? 710 LEU A C   1 
ATOM 5723 O O   . LEU B 2 710 ? 136.718 152.780 130.457 1.00 145.25 ? 710 LEU A O   1 
ATOM 5724 C CB  . LEU B 2 710 ? 137.818 151.015 133.124 1.00 149.30 ? 710 LEU A CB  1 
ATOM 5725 C CG  . LEU B 2 710 ? 138.102 151.596 134.511 1.00 146.20 ? 710 LEU A CG  1 
ATOM 5726 C CD1 . LEU B 2 710 ? 139.592 151.564 134.802 1.00 145.73 ? 710 LEU A CD1 1 
ATOM 5727 C CD2 . LEU B 2 710 ? 137.559 153.013 134.636 1.00 143.97 ? 710 LEU A CD2 1 
ATOM 5728 N N   . VAL B 2 711 ? 136.845 150.542 130.217 1.00 147.44 ? 711 VAL A N   1 
ATOM 5729 C CA  . VAL B 2 711 ? 137.026 150.664 128.773 1.00 148.90 ? 711 VAL A CA  1 
ATOM 5730 C C   . VAL B 2 711 ? 135.789 151.273 128.126 1.00 148.59 ? 711 VAL A C   1 
ATOM 5731 O O   . VAL B 2 711 ? 135.900 152.056 127.171 1.00 146.43 ? 711 VAL A O   1 
ATOM 5732 C CB  . VAL B 2 711 ? 137.389 149.301 128.147 1.00 150.00 ? 711 VAL A CB  1 
ATOM 5733 C CG1 . VAL B 2 711 ? 136.282 148.290 128.347 1.00 148.91 ? 711 VAL A CG1 1 
ATOM 5734 C CG2 . VAL B 2 711 ? 137.675 149.466 126.671 1.00 151.07 ? 711 VAL A CG2 1 
ATOM 5735 N N   . LEU B 2 712 ? 134.599 150.958 128.647 1.00 153.05 ? 712 LEU A N   1 
ATOM 5736 C CA  . LEU B 2 712 ? 133.368 151.462 128.056 1.00 153.28 ? 712 LEU A CA  1 
ATOM 5737 C C   . LEU B 2 712 ? 133.320 152.979 128.107 1.00 153.63 ? 712 LEU A C   1 
ATOM 5738 O O   . LEU B 2 712 ? 133.143 153.635 127.077 1.00 154.25 ? 712 LEU A O   1 
ATOM 5739 C CB  . LEU B 2 712 ? 132.162 150.857 128.776 1.00 152.37 ? 712 LEU A CB  1 
ATOM 5740 C CG  . LEU B 2 712 ? 130.818 150.856 128.043 1.00 154.12 ? 712 LEU A CG  1 
ATOM 5741 C CD1 . LEU B 2 712 ? 130.029 149.606 128.398 1.00 152.19 ? 712 LEU A CD1 1 
ATOM 5742 C CD2 . LEU B 2 712 ? 130.014 152.106 128.370 1.00 153.50 ? 712 LEU A CD2 1 
ATOM 5743 N N   . LEU B 2 713 ? 133.567 153.530 129.302 1.00 146.60 ? 713 LEU A N   1 
ATOM 5744 C CA  . LEU B 2 713 ? 133.483 154.991 129.546 1.00 146.35 ? 713 LEU A CA  1 
ATOM 5745 C C   . LEU B 2 713 ? 134.693 155.704 128.945 1.00 146.87 ? 713 LEU A C   1 
ATOM 5746 O O   . LEU B 2 713 ? 134.600 156.928 128.794 1.00 146.89 ? 713 LEU A O   1 
ATOM 5747 C CB  . LEU B 2 713 ? 133.414 155.176 131.058 1.00 146.82 ? 713 LEU A CB  1 
ATOM 5748 C CG  . LEU B 2 713 ? 132.226 154.505 131.753 1.00 150.45 ? 713 LEU A CG  1 
ATOM 5749 C CD1 . LEU B 2 713 ? 132.567 154.100 133.172 1.00 149.08 ? 713 LEU A CD1 1 
ATOM 5750 C CD2 . LEU B 2 713 ? 131.032 155.429 131.720 1.00 151.69 ? 713 LEU A CD2 1 
ATOM 5751 N N   . ASN B 2 714 ? 135.818 155.016 128.744 1.00 147.08 ? 714 ASN A N   1 
ATOM 5752 C CA  . ASN B 2 714 ? 136.955 155.606 128.043 1.00 149.44 ? 714 ASN A CA  1 
ATOM 5753 C C   . ASN B 2 714 ? 136.651 155.773 126.558 1.00 149.54 ? 714 ASN A C   1 
ATOM 5754 O O   . ASN B 2 714 ? 136.774 156.875 126.005 1.00 149.51 ? 714 ASN A O   1 
ATOM 5755 C CB  . ASN B 2 714 ? 138.209 154.761 128.258 1.00 149.27 ? 714 ASN A CB  1 
ATOM 5756 C CG  . ASN B 2 714 ? 138.723 154.836 129.682 1.00 147.72 ? 714 ASN A CG  1 
ATOM 5757 O OD1 . ASN B 2 714 ? 138.563 155.852 130.357 1.00 148.77 ? 714 ASN A OD1 1 
ATOM 5758 N ND2 . ASN B 2 714 ? 139.340 153.757 130.147 1.00 146.45 ? 714 ASN A ND2 1 
ATOM 5759 N N   . SER B 2 715 ? 136.215 154.692 125.901 1.00 149.75 ? 715 SER A N   1 
ATOM 5760 C CA  . SER B 2 715 ? 135.816 154.793 124.500 1.00 149.76 ? 715 SER A CA  1 
ATOM 5761 C C   . SER B 2 715 ? 134.643 155.746 124.327 1.00 148.21 ? 715 SER A C   1 
ATOM 5762 O O   . SER B 2 715 ? 134.541 156.433 123.303 1.00 146.81 ? 715 SER A O   1 
ATOM 5763 C CB  . SER B 2 715 ? 135.462 153.412 123.954 1.00 149.40 ? 715 SER A CB  1 
ATOM 5764 O OG  . SER B 2 715 ? 134.691 152.684 124.892 1.00 148.36 ? 715 SER A OG  1 
ATOM 5765 N N   . LEU B 2 716 ? 133.759 155.813 125.325 1.00 144.14 ? 716 LEU A N   1 
ATOM 5766 C CA  . LEU B 2 716 ? 132.661 156.771 125.297 1.00 144.03 ? 716 LEU A CA  1 
ATOM 5767 C C   . LEU B 2 716 ? 133.184 158.196 125.187 1.00 143.12 ? 716 LEU A C   1 
ATOM 5768 O O   . LEU B 2 716 ? 132.978 158.860 124.164 1.00 144.03 ? 716 LEU A O   1 
ATOM 5769 C CB  . LEU B 2 716 ? 131.798 156.572 126.545 1.00 144.72 ? 716 LEU A CB  1 
ATOM 5770 C CG  . LEU B 2 716 ? 130.539 157.367 126.874 1.00 144.87 ? 716 LEU A CG  1 
ATOM 5771 C CD1 . LEU B 2 716 ? 129.617 156.500 127.701 1.00 146.49 ? 716 LEU A CD1 1 
ATOM 5772 C CD2 . LEU B 2 716 ? 130.912 158.593 127.694 1.00 142.86 ? 716 LEU A CD2 1 
ATOM 5773 N N   . ALA B 2 717 ? 133.938 158.648 126.191 1.00 141.08 ? 717 ALA A N   1 
ATOM 5774 C CA  . ALA B 2 717 ? 134.481 160.003 126.159 1.00 142.31 ? 717 ALA A CA  1 
ATOM 5775 C C   . ALA B 2 717 ? 135.263 160.252 124.875 1.00 141.68 ? 717 ALA A C   1 
ATOM 5776 O O   . ALA B 2 717 ? 135.202 161.352 124.304 1.00 141.59 ? 717 ALA A O   1 
ATOM 5777 C CB  . ALA B 2 717 ? 135.358 160.246 127.386 1.00 139.91 ? 717 ALA A CB  1 
ATOM 5778 N N   . PHE B 2 718 ? 135.966 159.228 124.381 1.00 141.66 ? 718 PHE A N   1 
ATOM 5779 C CA  . PHE B 2 718 ? 136.649 159.368 123.100 1.00 142.79 ? 718 PHE A CA  1 
ATOM 5780 C C   . PHE B 2 718 ? 135.669 159.700 121.981 1.00 143.70 ? 718 PHE A C   1 
ATOM 5781 O O   . PHE B 2 718 ? 135.916 160.611 121.178 1.00 142.94 ? 718 PHE A O   1 
ATOM 5782 C CB  . PHE B 2 718 ? 137.443 158.099 122.783 1.00 142.84 ? 718 PHE A CB  1 
ATOM 5783 C CG  . PHE B 2 718 ? 138.793 158.053 123.445 1.00 142.70 ? 718 PHE A CG  1 
ATOM 5784 C CD1 . PHE B 2 718 ? 139.672 159.113 123.307 1.00 141.07 ? 718 PHE A CD1 1 
ATOM 5785 C CD2 . PHE B 2 718 ? 139.186 156.962 124.201 1.00 141.30 ? 718 PHE A CD2 1 
ATOM 5786 C CE1 . PHE B 2 718 ? 140.909 159.089 123.913 1.00 140.66 ? 718 PHE A CE1 1 
ATOM 5787 C CE2 . PHE B 2 718 ? 140.428 156.933 124.807 1.00 141.61 ? 718 PHE A CE2 1 
ATOM 5788 C CZ  . PHE B 2 718 ? 141.291 157.997 124.662 1.00 142.82 ? 718 PHE A CZ  1 
ATOM 5789 N N   . LEU B 2 719 ? 134.529 159.006 121.935 1.00 148.16 ? 719 LEU A N   1 
ATOM 5790 C CA  . LEU B 2 719 ? 133.602 159.229 120.832 1.00 148.67 ? 719 LEU A CA  1 
ATOM 5791 C C   . LEU B 2 719 ? 132.892 160.575 120.969 1.00 145.92 ? 719 LEU A C   1 
ATOM 5792 O O   . LEU B 2 719 ? 132.636 161.244 119.963 1.00 144.99 ? 719 LEU A O   1 
ATOM 5793 C CB  . LEU B 2 719 ? 132.609 158.065 120.725 1.00 148.44 ? 719 LEU A CB  1 
ATOM 5794 C CG  . LEU B 2 719 ? 131.482 157.726 121.711 1.00 148.00 ? 719 LEU A CG  1 
ATOM 5795 C CD1 . LEU B 2 719 ? 130.339 158.743 121.714 1.00 146.30 ? 719 LEU A CD1 1 
ATOM 5796 C CD2 . LEU B 2 719 ? 130.959 156.318 121.463 1.00 146.85 ? 719 LEU A CD2 1 
ATOM 5797 N N   . LEU B 2 720 ? 132.575 161.002 122.199 1.00 140.91 ? 720 LEU A N   1 
ATOM 5798 C CA  . LEU B 2 720 ? 132.007 162.345 122.350 1.00 139.98 ? 720 LEU A CA  1 
ATOM 5799 C C   . LEU B 2 720 ? 132.992 163.426 121.921 1.00 142.27 ? 720 LEU A C   1 
ATOM 5800 O O   . LEU B 2 720 ? 132.595 164.371 121.232 1.00 144.59 ? 720 LEU A O   1 
ATOM 5801 C CB  . LEU B 2 720 ? 131.489 162.636 123.765 1.00 139.79 ? 720 LEU A CB  1 
ATOM 5802 C CG  . LEU B 2 720 ? 130.390 161.884 124.528 1.00 144.63 ? 720 LEU A CG  1 
ATOM 5803 C CD1 . LEU B 2 720 ? 130.680 160.458 124.797 1.00 143.51 ? 720 LEU A CD1 1 
ATOM 5804 C CD2 . LEU B 2 720 ? 130.083 162.619 125.839 1.00 145.08 ? 720 LEU A CD2 1 
ATOM 5805 N N   . MET B 2 721 ? 134.270 163.339 122.311 1.00 145.55 ? 721 MET A N   1 
ATOM 5806 C CA  . MET B 2 721 ? 135.134 164.426 121.848 1.00 147.02 ? 721 MET A CA  1 
ATOM 5807 C C   . MET B 2 721 ? 135.394 164.346 120.345 1.00 146.99 ? 721 MET A C   1 
ATOM 5808 O O   . MET B 2 721 ? 135.533 165.388 119.690 1.00 147.65 ? 721 MET A O   1 
ATOM 5809 C CB  . MET B 2 721 ? 136.452 164.542 122.630 1.00 146.22 ? 721 MET A CB  1 
ATOM 5810 N N   . ALA B 2 722 ? 135.419 163.141 119.768 1.00 147.53 ? 722 ALA A N   1 
ATOM 5811 C CA  . ALA B 2 722 ? 135.499 163.040 118.313 1.00 149.58 ? 722 ALA A CA  1 
ATOM 5812 C C   . ALA B 2 722 ? 134.303 163.698 117.631 1.00 152.39 ? 722 ALA A C   1 
ATOM 5813 O O   . ALA B 2 722 ? 134.459 164.456 116.665 1.00 152.76 ? 722 ALA A O   1 
ATOM 5814 C CB  . ALA B 2 722 ? 135.611 161.570 117.911 1.00 148.54 ? 722 ALA A CB  1 
ATOM 5815 N N   . VAL B 2 723 ? 133.096 163.431 118.136 1.00 150.36 ? 723 VAL A N   1 
ATOM 5816 C CA  . VAL B 2 723 ? 131.890 164.027 117.567 1.00 147.98 ? 723 VAL A CA  1 
ATOM 5817 C C   . VAL B 2 723 ? 131.924 165.542 117.714 1.00 145.73 ? 723 VAL A C   1 
ATOM 5818 O O   . VAL B 2 723 ? 131.554 166.281 116.793 1.00 147.85 ? 723 VAL A O   1 
ATOM 5819 C CB  . VAL B 2 723 ? 130.638 163.421 118.228 1.00 146.52 ? 723 VAL A CB  1 
ATOM 5820 C CG1 . VAL B 2 723 ? 129.447 164.358 118.096 1.00 146.56 ? 723 VAL A CG1 1 
ATOM 5821 C CG2 . VAL B 2 723 ? 130.320 162.065 117.621 1.00 146.10 ? 723 VAL A CG2 1 
ATOM 5822 N N   . ILE B 2 724 ? 132.364 166.029 118.875 1.00 138.35 ? 724 ILE A N   1 
ATOM 5823 C CA  . ILE B 2 724 ? 132.407 167.469 119.107 1.00 139.65 ? 724 ILE A CA  1 
ATOM 5824 C C   . ILE B 2 724 ? 133.345 168.139 118.111 1.00 139.87 ? 724 ILE A C   1 
ATOM 5825 O O   . ILE B 2 724 ? 132.976 169.116 117.447 1.00 143.04 ? 724 ILE A O   1 
ATOM 5826 C CB  . ILE B 2 724 ? 132.814 167.766 120.561 1.00 141.80 ? 724 ILE A CB  1 
ATOM 5827 C CG1 . ILE B 2 724 ? 131.679 167.396 121.516 1.00 142.25 ? 724 ILE A CG1 1 
ATOM 5828 C CG2 . ILE B 2 724 ? 133.165 169.229 120.730 1.00 142.07 ? 724 ILE A CG2 1 
ATOM 5829 C CD1 . ILE B 2 724 ? 132.138 167.121 122.931 1.00 141.49 ? 724 ILE A CD1 1 
ATOM 5830 N N   . TYR B 2 725 ? 134.567 167.613 117.975 1.00 145.62 ? 725 TYR A N   1 
ATOM 5831 C CA  . TYR B 2 725 ? 135.505 168.225 117.039 1.00 151.49 ? 725 TYR A CA  1 
ATOM 5832 C C   . TYR B 2 725 ? 135.036 168.086 115.597 1.00 153.74 ? 725 TYR A C   1 
ATOM 5833 O O   . TYR B 2 725 ? 135.311 168.966 114.775 1.00 152.41 ? 725 TYR A O   1 
ATOM 5834 C CB  . TYR B 2 725 ? 136.905 167.644 117.220 1.00 150.87 ? 725 TYR A CB  1 
ATOM 5835 C CG  . TYR B 2 725 ? 137.838 168.619 117.896 1.00 149.84 ? 725 TYR A CG  1 
ATOM 5836 C CD1 . TYR B 2 725 ? 137.556 169.104 119.162 1.00 148.60 ? 725 TYR A CD1 1 
ATOM 5837 C CD2 . TYR B 2 725 ? 138.986 169.072 117.262 1.00 150.29 ? 725 TYR A CD2 1 
ATOM 5838 C CE1 . TYR B 2 725 ? 138.392 170.002 119.788 1.00 150.44 ? 725 TYR A CE1 1 
ATOM 5839 C CE2 . TYR B 2 725 ? 139.832 169.973 117.881 1.00 150.67 ? 725 TYR A CE2 1 
ATOM 5840 C CZ  . TYR B 2 725 ? 139.528 170.433 119.144 1.00 150.65 ? 725 TYR A CZ  1 
ATOM 5841 O OH  . TYR B 2 725 ? 140.361 171.328 119.772 1.00 148.35 ? 725 TYR A OH  1 
ATOM 5842 N N   . THR B 2 726 ? 134.305 167.016 115.277 1.00 164.03 ? 726 THR A N   1 
ATOM 5843 C CA  . THR B 2 726 ? 133.657 166.944 113.972 1.00 163.62 ? 726 THR A CA  1 
ATOM 5844 C C   . THR B 2 726 ? 132.660 168.083 113.802 1.00 163.21 ? 726 THR A C   1 
ATOM 5845 O O   . THR B 2 726 ? 132.545 168.666 112.717 1.00 162.62 ? 726 THR A O   1 
ATOM 5846 C CB  . THR B 2 726 ? 132.960 165.593 113.806 1.00 163.13 ? 726 THR A CB  1 
ATOM 5847 O OG1 . THR B 2 726 ? 133.839 164.544 114.229 1.00 163.36 ? 726 THR A OG1 1 
ATOM 5848 C CG2 . THR B 2 726 ? 132.571 165.367 112.353 1.00 161.62 ? 726 THR A CG2 1 
ATOM 5849 N N   . LYS B 2 727 ? 131.929 168.410 114.869 1.00 161.42 ? 727 LYS A N   1 
ATOM 5850 C CA  . LYS B 2 727 ? 130.972 169.510 114.809 1.00 159.46 ? 727 LYS A CA  1 
ATOM 5851 C C   . LYS B 2 727 ? 131.577 170.878 114.511 1.00 159.15 ? 727 LYS A C   1 
ATOM 5852 O O   . LYS B 2 727 ? 131.051 171.623 113.678 1.00 160.74 ? 727 LYS A O   1 
ATOM 5853 C CB  . LYS B 2 727 ? 130.139 169.555 116.090 1.00 159.05 ? 727 LYS A CB  1 
ATOM 5854 C CG  . LYS B 2 727 ? 128.691 169.127 115.905 1.00 158.88 ? 727 LYS A CG  1 
ATOM 5855 C CD  . LYS B 2 727 ? 128.574 167.919 114.988 1.00 159.41 ? 727 LYS A CD  1 
ATOM 5856 C CE  . LYS B 2 727 ? 127.130 167.687 114.571 1.00 158.37 ? 727 LYS A CE  1 
ATOM 5857 N NZ  . LYS B 2 727 ? 127.012 166.630 113.528 1.00 156.99 ? 727 LYS A NZ  1 
ATOM 5858 N N   . LEU B 2 728 ? 132.675 171.235 115.187 1.00 156.40 ? 728 LEU A N   1 
ATOM 5859 C CA  . LEU B 2 728 ? 133.317 172.507 114.836 1.00 156.67 ? 728 LEU A CA  1 
ATOM 5860 C C   . LEU B 2 728 ? 134.021 172.464 113.476 1.00 157.31 ? 728 LEU A C   1 
ATOM 5861 O O   . LEU B 2 728 ? 134.136 173.484 112.788 1.00 159.61 ? 728 LEU A O   1 
ATOM 5862 C CB  . LEU B 2 728 ? 134.365 172.965 115.859 1.00 155.76 ? 728 LEU A CB  1 
ATOM 5863 C CG  . LEU B 2 728 ? 135.645 172.215 116.249 1.00 156.68 ? 728 LEU A CG  1 
ATOM 5864 C CD1 . LEU B 2 728 ? 136.740 172.442 115.203 1.00 155.69 ? 728 LEU A CD1 1 
ATOM 5865 C CD2 . LEU B 2 728 ? 136.134 172.428 117.654 1.00 156.31 ? 728 LEU A CD2 1 
ATOM 5866 N N   . TYR B 2 729 ? 134.484 171.280 113.068 1.00 160.60 ? 729 TYR A N   1 
ATOM 5867 C CA  . TYR B 2 729 ? 135.085 171.149 111.745 1.00 162.49 ? 729 TYR A CA  1 
ATOM 5868 C C   . TYR B 2 729 ? 133.993 171.478 110.736 1.00 165.04 ? 729 TYR A C   1 
ATOM 5869 O O   . TYR B 2 729 ? 134.237 172.184 109.751 1.00 163.96 ? 729 TYR A O   1 
ATOM 5870 C CB  . TYR B 2 729 ? 135.677 169.769 111.465 1.00 162.81 ? 729 TYR A CB  1 
ATOM 5871 C CG  . TYR B 2 729 ? 136.521 169.719 110.213 1.00 166.09 ? 729 TYR A CG  1 
ATOM 5872 C CD1 . TYR B 2 729 ? 137.178 170.852 109.753 1.00 165.14 ? 729 TYR A CD1 1 
ATOM 5873 C CD2 . TYR B 2 729 ? 136.656 168.544 109.487 1.00 164.63 ? 729 TYR A CD2 1 
ATOM 5874 C CE1 . TYR B 2 729 ? 137.949 170.817 108.608 1.00 164.30 ? 729 TYR A CE1 1 
ATOM 5875 C CE2 . TYR B 2 729 ? 137.426 168.498 108.339 1.00 164.57 ? 729 TYR A CE2 1 
ATOM 5876 C CZ  . TYR B 2 729 ? 138.070 169.637 107.905 1.00 165.22 ? 729 TYR A CZ  1 
ATOM 5877 O OH  . TYR B 2 729 ? 138.838 169.599 106.765 1.00 161.79 ? 729 TYR A OH  1 
ATOM 5878 N N   . CYS B 2 730 ? 132.781 170.968 110.964 1.00 172.56 ? 730 CYS A N   1 
ATOM 5879 C CA  . CYS B 2 730 ? 131.656 171.314 110.101 1.00 171.82 ? 730 CYS A CA  1 
ATOM 5880 C C   . CYS B 2 730 ? 131.305 172.793 110.214 1.00 170.84 ? 730 CYS A C   1 
ATOM 5881 O O   . CYS B 2 730 ? 130.959 173.433 109.214 1.00 170.55 ? 730 CYS A O   1 
ATOM 5882 C CB  . CYS B 2 730 ? 130.446 170.447 110.446 1.00 170.32 ? 730 CYS A CB  1 
ATOM 5883 S SG  . CYS B 2 730 ? 130.548 168.745 109.848 1.00 173.71 ? 730 CYS A SG  1 
ATOM 5884 N N   . ASN B 2 731 ? 131.378 173.350 111.426 1.00 163.38 ? 731 ASN A N   1 
ATOM 5885 C CA  . ASN B 2 731 ? 130.977 174.738 111.634 1.00 161.28 ? 731 ASN A CA  1 
ATOM 5886 C C   . ASN B 2 731 ? 131.890 175.706 110.891 1.00 161.91 ? 731 ASN A C   1 
ATOM 5887 O O   . ASN B 2 731 ? 131.417 176.680 110.294 1.00 159.05 ? 731 ASN A O   1 
ATOM 5888 C CB  . ASN B 2 731 ? 130.960 175.060 113.128 1.00 160.38 ? 731 ASN A CB  1 
ATOM 5889 C CG  . ASN B 2 731 ? 129.749 174.485 113.833 1.00 161.95 ? 731 ASN A CG  1 
ATOM 5890 O OD1 . ASN B 2 731 ? 129.059 173.617 113.298 1.00 162.81 ? 731 ASN A OD1 1 
ATOM 5891 N ND2 . ASN B 2 731 ? 129.483 174.967 115.041 1.00 160.86 ? 731 ASN A ND2 1 
ATOM 5892 N N   . LEU B 2 732 ? 133.197 175.463 110.917 1.00 157.39 ? 732 LEU A N   1 
ATOM 5893 C CA  . LEU B 2 732 ? 134.140 176.369 110.268 1.00 154.29 ? 732 LEU A CA  1 
ATOM 5894 C C   . LEU B 2 732 ? 134.086 176.213 108.753 1.00 153.01 ? 732 LEU A C   1 
ATOM 5895 O O   . LEU B 2 732 ? 133.848 175.119 108.241 1.00 153.68 ? 732 LEU A O   1 
ATOM 5896 C CB  . LEU B 2 732 ? 135.566 176.129 110.775 1.00 153.07 ? 732 LEU A CB  1 
ATOM 5897 C CG  . LEU B 2 732 ? 136.114 174.700 110.771 1.00 153.64 ? 732 LEU A CG  1 
ATOM 5898 C CD1 . LEU B 2 732 ? 136.859 174.403 109.477 1.00 151.42 ? 732 LEU A CD1 1 
ATOM 5899 C CD2 . LEU B 2 732 ? 137.017 174.471 111.973 1.00 152.29 ? 732 LEU A CD2 1 
ATOM 5900 N N   . SER B 2 741 ? 146.369 182.963 117.649 1.00 165.34 ? 741 SER A N   1 
ATOM 5901 C CA  . SER B 2 741 ? 145.061 183.485 118.026 1.00 166.09 ? 741 SER A CA  1 
ATOM 5902 C C   . SER B 2 741 ? 144.180 182.385 118.606 1.00 166.93 ? 741 SER A C   1 
ATOM 5903 O O   . SER B 2 741 ? 144.636 181.263 118.827 1.00 167.76 ? 741 SER A O   1 
ATOM 5904 C CB  . SER B 2 741 ? 144.371 184.128 116.820 1.00 164.27 ? 741 SER A CB  1 
ATOM 5905 O OG  . SER B 2 741 ? 143.608 183.175 116.101 1.00 162.34 ? 741 SER A OG  1 
ATOM 5906 N N   . GLN B 2 742 ? 142.912 182.721 118.855 1.00 168.12 ? 742 GLN A N   1 
ATOM 5907 C CA  . GLN B 2 742 ? 141.971 181.730 119.368 1.00 169.35 ? 742 GLN A CA  1 
ATOM 5908 C C   . GLN B 2 742 ? 141.747 180.610 118.359 1.00 170.95 ? 742 GLN A C   1 
ATOM 5909 O O   . GLN B 2 742 ? 141.565 179.448 118.742 1.00 170.76 ? 742 GLN A O   1 
ATOM 5910 C CB  . GLN B 2 742 ? 140.649 182.407 119.734 1.00 167.96 ? 742 GLN A CB  1 
ATOM 5911 C CG  . GLN B 2 742 ? 139.497 181.447 119.981 1.00 168.89 ? 742 GLN A CG  1 
ATOM 5912 C CD  . GLN B 2 742 ? 139.758 180.511 121.145 1.00 170.16 ? 742 GLN A CD  1 
ATOM 5913 O OE1 . GLN B 2 742 ? 139.432 179.326 121.089 1.00 171.26 ? 742 GLN A OE1 1 
ATOM 5914 N NE2 . GLN B 2 742 ? 140.349 181.041 122.209 1.00 169.32 ? 742 GLN A NE2 1 
ATOM 5915 N N   . SER B 2 743 ? 141.764 180.941 117.065 1.00 171.13 ? 743 SER A N   1 
ATOM 5916 C CA  . SER B 2 743 ? 141.616 179.917 116.036 1.00 170.29 ? 743 SER A CA  1 
ATOM 5917 C C   . SER B 2 743 ? 142.744 178.896 116.110 1.00 170.54 ? 743 SER A C   1 
ATOM 5918 O O   . SER B 2 743 ? 142.516 177.693 115.938 1.00 168.30 ? 743 SER A O   1 
ATOM 5919 C CB  . SER B 2 743 ? 141.566 180.568 114.654 1.00 168.10 ? 743 SER A CB  1 
ATOM 5920 O OG  . SER B 2 743 ? 142.805 181.174 114.331 1.00 165.86 ? 743 SER A OG  1 
ATOM 5921 N N   . SER B 2 744 ? 143.966 179.356 116.360 1.00 168.23 ? 744 SER A N   1 
ATOM 5922 C CA  . SER B 2 744 ? 145.085 178.445 116.527 1.00 165.40 ? 744 SER A CA  1 
ATOM 5923 C C   . SER B 2 744 ? 144.993 177.732 117.876 1.00 165.13 ? 744 SER A C   1 
ATOM 5924 O O   . SER B 2 744 ? 144.132 178.026 118.711 1.00 166.52 ? 744 SER A O   1 
ATOM 5925 C CB  . SER B 2 744 ? 146.410 179.196 116.408 1.00 163.91 ? 744 SER A CB  1 
ATOM 5926 O OG  . SER B 2 744 ? 146.737 179.845 117.624 1.00 165.00 ? 744 SER A OG  1 
ATOM 5927 N N   . MET B 2 745 ? 145.880 176.749 118.056 1.00 147.07 ? 745 MET A N   1 
ATOM 5928 C CA  . MET B 2 745 ? 146.033 175.974 119.286 1.00 147.65 ? 745 MET A CA  1 
ATOM 5929 C C   . MET B 2 745 ? 144.866 175.000 119.452 1.00 147.15 ? 745 MET A C   1 
ATOM 5930 O O   . MET B 2 745 ? 144.913 174.092 120.289 1.00 147.25 ? 745 MET A O   1 
ATOM 5931 C CB  . MET B 2 745 ? 146.192 176.924 120.488 1.00 149.37 ? 745 MET A CB  1 
ATOM 5932 C CG  . MET B 2 745 ? 145.726 176.417 121.846 1.00 150.60 ? 745 MET A CG  1 
ATOM 5933 S SD  . MET B 2 745 ? 146.637 177.180 123.202 1.00 157.64 ? 745 MET A SD  1 
ATOM 5934 C CE  . MET B 2 745 ? 146.209 176.091 124.558 1.00 147.92 ? 745 MET A CE  1 
ATOM 5935 N N   . ILE B 2 746 ? 143.847 175.129 118.601 1.00 137.90 ? 746 ILE A N   1 
ATOM 5936 C CA  . ILE B 2 746 ? 142.805 174.110 118.535 1.00 137.44 ? 746 ILE A CA  1 
ATOM 5937 C C   . ILE B 2 746 ? 143.364 172.830 117.930 1.00 139.32 ? 746 ILE A C   1 
ATOM 5938 O O   . ILE B 2 746 ? 143.035 171.717 118.366 1.00 139.97 ? 746 ILE A O   1 
ATOM 5939 C CB  . ILE B 2 746 ? 141.598 174.640 117.739 1.00 137.71 ? 746 ILE A CB  1 
ATOM 5940 C CG1 . ILE B 2 746 ? 141.006 175.871 118.425 1.00 137.75 ? 746 ILE A CG1 1 
ATOM 5941 C CG2 . ILE B 2 746 ? 140.544 173.562 117.571 1.00 136.93 ? 746 ILE A CG2 1 
ATOM 5942 C CD1 . ILE B 2 746 ? 139.951 176.576 117.602 1.00 138.20 ? 746 ILE A CD1 1 
ATOM 5943 N N   . LYS B 2 747 ? 144.230 172.969 116.923 1.00 141.78 ? 747 LYS A N   1 
ATOM 5944 C CA  . LYS B 2 747 ? 144.890 171.809 116.340 1.00 145.07 ? 747 LYS A CA  1 
ATOM 5945 C C   . LYS B 2 747 ? 145.739 171.076 117.367 1.00 148.90 ? 747 LYS A C   1 
ATOM 5946 O O   . LYS B 2 747 ? 145.946 169.865 117.248 1.00 148.70 ? 747 LYS A O   1 
ATOM 5947 C CB  . LYS B 2 747 ? 145.748 172.240 115.152 1.00 143.97 ? 747 LYS A CB  1 
ATOM 5948 C CG  . LYS B 2 747 ? 146.496 173.543 115.378 1.00 141.08 ? 747 LYS A CG  1 
ATOM 5949 C CD  . LYS B 2 747 ? 147.607 173.728 114.359 1.00 142.73 ? 747 LYS A CD  1 
ATOM 5950 C CE  . LYS B 2 747 ? 147.101 173.520 112.941 1.00 144.58 ? 747 LYS A CE  1 
ATOM 5951 N NZ  . LYS B 2 747 ? 148.221 173.424 111.965 1.00 141.96 ? 747 LYS A NZ  1 
ATOM 5952 N N   . HIS B 2 748 ? 146.237 171.786 118.381 1.00 140.63 ? 748 HIS A N   1 
ATOM 5953 C CA  . HIS B 2 748 ? 146.982 171.123 119.446 1.00 137.34 ? 748 HIS A CA  1 
ATOM 5954 C C   . HIS B 2 748 ? 146.109 170.131 120.205 1.00 135.70 ? 748 HIS A C   1 
ATOM 5955 O O   . HIS B 2 748 ? 146.510 168.987 120.445 1.00 138.38 ? 748 HIS A O   1 
ATOM 5956 C CB  . HIS B 2 748 ? 147.574 172.160 120.398 1.00 136.03 ? 748 HIS A CB  1 
ATOM 5957 C CG  . HIS B 2 748 ? 148.467 171.572 121.443 1.00 138.12 ? 748 HIS A CG  1 
ATOM 5958 N ND1 . HIS B 2 748 ? 148.239 171.733 122.793 1.00 139.26 ? 748 HIS A ND1 1 
ATOM 5959 C CD2 . HIS B 2 748 ? 149.584 170.815 121.337 1.00 138.29 ? 748 HIS A CD2 1 
ATOM 5960 C CE1 . HIS B 2 748 ? 149.182 171.105 123.473 1.00 136.99 ? 748 HIS A CE1 1 
ATOM 5961 N NE2 . HIS B 2 748 ? 150.009 170.539 122.613 1.00 136.71 ? 748 HIS A NE2 1 
ATOM 5962 N N   . VAL B 2 749 ? 144.910 170.596 120.550 1.00 117.52 ? 749 VAL A N   1 
ATOM 5963 C CA  . VAL B 2 749 ? 143.957 169.726 121.272 1.00 117.85 ? 749 VAL A CA  1 
ATOM 5964 C C   . VAL B 2 749 ? 143.559 168.609 120.310 1.00 120.67 ? 749 VAL A C   1 
ATOM 5965 O O   . VAL B 2 749 ? 143.465 167.544 120.773 1.00 121.51 ? 749 VAL A O   1 
ATOM 5966 C CB  . VAL B 2 749 ? 142.736 170.480 121.796 1.00 121.34 ? 749 VAL A CB  1 
ATOM 5967 C CG1 . VAL B 2 749 ? 141.610 169.540 122.202 1.00 124.52 ? 749 VAL A CG1 1 
ATOM 5968 C CG2 . VAL B 2 749 ? 143.113 171.397 122.945 1.00 125.13 ? 749 VAL A CG2 1 
ATOM 5969 N N   . ALA B 2 750 ? 143.401 168.850 119.021 1.00 126.57 ? 750 ALA A N   1 
ATOM 5970 C CA  . ALA B 2 750 ? 143.054 167.821 118.045 1.00 128.06 ? 750 ALA A CA  1 
ATOM 5971 C C   . ALA B 2 750 ? 144.126 166.739 118.017 1.00 129.39 ? 750 ALA A C   1 
ATOM 5972 O O   . ALA B 2 750 ? 143.820 165.541 118.039 1.00 129.83 ? 750 ALA A O   1 
ATOM 5973 C CB  . ALA B 2 750 ? 142.870 168.436 116.659 1.00 129.91 ? 750 ALA A CB  1 
ATOM 5974 N N   . TRP B 2 751 ? 145.396 167.148 117.982 1.00 129.31 ? 751 TRP A N   1 
ATOM 5975 C CA  . TRP B 2 751 ? 146.494 166.188 117.998 1.00 127.85 ? 751 TRP A CA  1 
ATOM 5976 C C   . TRP B 2 751 ? 146.540 165.424 119.314 1.00 128.34 ? 751 TRP A C   1 
ATOM 5977 O O   . TRP B 2 751 ? 146.879 164.235 119.339 1.00 128.69 ? 751 TRP A O   1 
ATOM 5978 C CB  . TRP B 2 751 ? 147.821 166.904 117.748 1.00 122.72 ? 751 TRP A CB  1 
ATOM 5979 C CG  . TRP B 2 751 ? 148.133 167.101 116.298 1.00 128.04 ? 751 TRP A CG  1 
ATOM 5980 C CD1 . TRP B 2 751 ? 147.280 167.535 115.328 1.00 127.34 ? 751 TRP A CD1 1 
ATOM 5981 C CD2 . TRP B 2 751 ? 149.390 166.867 115.652 1.00 134.89 ? 751 TRP A CD2 1 
ATOM 5982 N NE1 . TRP B 2 751 ? 147.927 167.587 114.117 1.00 129.70 ? 751 TRP A NE1 1 
ATOM 5983 C CE2 . TRP B 2 751 ? 149.224 167.182 114.290 1.00 133.01 ? 751 TRP A CE2 1 
ATOM 5984 C CE3 . TRP B 2 751 ? 150.640 166.422 116.094 1.00 134.24 ? 751 TRP A CE3 1 
ATOM 5985 C CZ2 . TRP B 2 751 ? 150.261 167.067 113.366 1.00 129.45 ? 751 TRP A CZ2 1 
ATOM 5986 C CZ3 . TRP B 2 751 ? 151.668 166.309 115.175 1.00 124.57 ? 751 TRP A CZ3 1 
ATOM 5987 C CH2 . TRP B 2 751 ? 151.472 166.630 113.827 1.00 124.91 ? 751 TRP A CH2 1 
ATOM 5988 N N   . LEU B 2 752 ? 146.218 166.096 120.422 1.00 118.65 ? 752 LEU A N   1 
ATOM 5989 C CA  . LEU B 2 752 ? 146.163 165.414 121.710 1.00 115.07 ? 752 LEU A CA  1 
ATOM 5990 C C   . LEU B 2 752 ? 145.145 164.281 121.683 1.00 117.39 ? 752 LEU A C   1 
ATOM 5991 O O   . LEU B 2 752 ? 145.447 163.148 122.080 1.00 121.58 ? 752 LEU A O   1 
ATOM 5992 C CB  . LEU B 2 752 ? 145.828 166.410 122.820 1.00 109.36 ? 752 LEU A CB  1 
ATOM 5993 C CG  . LEU B 2 752 ? 146.979 166.833 123.731 1.00 108.97 ? 752 LEU A CG  1 
ATOM 5994 C CD1 . LEU B 2 752 ? 148.047 167.570 122.944 1.00 110.37 ? 752 LEU A CD1 1 
ATOM 5995 C CD2 . LEU B 2 752 ? 146.466 167.691 124.873 1.00 114.25 ? 752 LEU A CD2 1 
ATOM 5996 N N   . ILE B 2 753 ? 143.944 164.587 121.166 1.00 123.78 ? 753 ILE A N   1 
ATOM 5997 C CA  . ILE B 2 753 ? 142.825 163.601 121.076 1.00 126.34 ? 753 ILE A CA  1 
ATOM 5998 C C   . ILE B 2 753 ? 143.242 162.486 120.112 1.00 126.36 ? 753 ILE A C   1 
ATOM 5999 O O   . ILE B 2 753 ? 142.804 161.358 120.329 1.00 127.29 ? 753 ILE A O   1 
ATOM 6000 C CB  . ILE B 2 753 ? 141.528 164.273 120.579 1.00 125.32 ? 753 ILE A CB  1 
ATOM 6001 C CG1 . ILE B 2 753 ? 141.075 165.445 121.449 1.00 128.25 ? 753 ILE A CG1 1 
ATOM 6002 C CG2 . ILE B 2 753 ? 140.409 163.243 120.435 1.00 122.50 ? 753 ILE A CG2 1 
ATOM 6003 C CD1 . ILE B 2 753 ? 140.261 166.487 120.706 1.00 125.34 ? 753 ILE A CD1 1 
ATOM 6004 N N   . PHE B 2 754 ? 143.949 162.814 119.031 1.00 127.47 ? 754 PHE A N   1 
ATOM 6005 C CA  . PHE B 2 754 ? 144.435 161.839 118.059 1.00 128.55 ? 754 PHE A CA  1 
ATOM 6006 C C   . PHE B 2 754 ? 145.384 160.845 118.721 1.00 128.58 ? 754 PHE A C   1 
ATOM 6007 O O   . PHE B 2 754 ? 145.147 159.627 118.706 1.00 129.19 ? 754 PHE A O   1 
ATOM 6008 C CB  . PHE B 2 754 ? 145.128 162.596 116.920 1.00 128.87 ? 754 PHE A CB  1 
ATOM 6009 C CG  . PHE B 2 754 ? 145.609 161.734 115.780 1.00 131.87 ? 754 PHE A CG  1 
ATOM 6010 C CD1 . PHE B 2 754 ? 146.437 162.275 114.810 1.00 129.46 ? 754 PHE A CD1 1 
ATOM 6011 C CD2 . PHE B 2 754 ? 145.192 160.423 115.633 1.00 131.79 ? 754 PHE A CD2 1 
ATOM 6012 C CE1 . PHE B 2 754 ? 146.881 161.515 113.748 1.00 130.41 ? 754 PHE A CE1 1 
ATOM 6013 C CE2 . PHE B 2 754 ? 145.633 159.657 114.569 1.00 130.36 ? 754 PHE A CE2 1 
ATOM 6014 C CZ  . PHE B 2 754 ? 146.476 160.205 113.626 1.00 132.04 ? 754 PHE A CZ  1 
ATOM 6015 N N   . THR B 2 755 ? 146.453 161.356 119.335 1.00 125.71 ? 755 THR A N   1 
ATOM 6016 C CA  . THR B 2 755 ? 147.458 160.485 119.934 1.00 126.38 ? 755 THR A CA  1 
ATOM 6017 C C   . THR B 2 755 ? 146.865 159.655 121.063 1.00 124.64 ? 755 THR A C   1 
ATOM 6018 O O   . THR B 2 755 ? 147.095 158.442 121.141 1.00 127.23 ? 755 THR A O   1 
ATOM 6019 C CB  . THR B 2 755 ? 148.639 161.311 120.442 1.00 125.07 ? 755 THR A CB  1 
ATOM 6020 O OG1 . THR B 2 755 ? 148.186 162.230 121.444 1.00 127.07 ? 755 THR A OG1 1 
ATOM 6021 C CG2 . THR B 2 755 ? 149.283 162.082 119.301 1.00 127.70 ? 755 THR A CG2 1 
ATOM 6022 N N   . ASN B 2 756 ? 146.087 160.289 121.946 1.00 117.54 ? 756 ASN A N   1 
ATOM 6023 C CA  . ASN B 2 756 ? 145.556 159.568 123.097 1.00 119.00 ? 756 ASN A CA  1 
ATOM 6024 C C   . ASN B 2 756 ? 144.622 158.445 122.668 1.00 121.87 ? 756 ASN A C   1 
ATOM 6025 O O   . ASN B 2 756 ? 144.695 157.333 123.202 1.00 123.45 ? 756 ASN A O   1 
ATOM 6026 C CB  . ASN B 2 756 ? 144.815 160.511 124.042 1.00 118.27 ? 756 ASN A CB  1 
ATOM 6027 C CG  . ASN B 2 756 ? 145.728 161.125 125.081 1.00 118.24 ? 756 ASN A CG  1 
ATOM 6028 O OD1 . ASN B 2 756 ? 145.550 160.919 126.281 1.00 115.05 ? 756 ASN A OD1 1 
ATOM 6029 N ND2 . ASN B 2 756 ? 146.719 161.881 124.624 1.00 118.58 ? 756 ASN A ND2 1 
ATOM 6030 N N   . CYS B 2 757 ? 143.752 158.703 121.690 1.00 135.79 ? 757 CYS A N   1 
ATOM 6031 C CA  . CYS B 2 757 ? 142.816 157.671 121.262 1.00 136.16 ? 757 CYS A CA  1 
ATOM 6032 C C   . CYS B 2 757 ? 143.541 156.527 120.564 1.00 134.21 ? 757 CYS A C   1 
ATOM 6033 O O   . CYS B 2 757 ? 143.290 155.352 120.866 1.00 134.04 ? 757 CYS A O   1 
ATOM 6034 C CB  . CYS B 2 757 ? 141.739 158.273 120.358 1.00 137.04 ? 757 CYS A CB  1 
ATOM 6035 S SG  . CYS B 2 757 ? 142.233 158.550 118.647 1.00 146.72 ? 757 CYS A SG  1 
ATOM 6036 N N   . ILE B 2 758 ? 144.473 156.856 119.659 1.00 132.79 ? 758 ILE A N   1 
ATOM 6037 C CA  . ILE B 2 758 ? 145.177 155.804 118.866 1.00 135.64 ? 758 ILE A CA  1 
ATOM 6038 C C   . ILE B 2 758 ? 146.077 155.008 119.817 1.00 136.22 ? 758 ILE A C   1 
ATOM 6039 O O   . ILE B 2 758 ? 146.367 153.850 119.465 1.00 136.84 ? 758 ILE A O   1 
ATOM 6040 C CB  . ILE B 2 758 ? 145.963 156.363 117.664 1.00 134.91 ? 758 ILE A CB  1 
ATOM 6041 C CG1 . ILE B 2 758 ? 147.131 157.258 118.092 1.00 132.31 ? 758 ILE A CG1 1 
ATOM 6042 C CG2 . ILE B 2 758 ? 145.003 157.046 116.691 1.00 133.73 ? 758 ILE A CG2 1 
ATOM 6043 C CD1 . ILE B 2 758 ? 147.676 158.166 117.005 1.00 131.02 ? 758 ILE A CD1 1 
ATOM 6044 N N   . PHE B 2 759 ? 146.514 155.584 120.946 1.00 130.36 ? 759 PHE A N   1 
ATOM 6045 C CA  . PHE B 2 759 ? 147.271 154.812 121.919 1.00 128.51 ? 759 PHE A CA  1 
ATOM 6046 C C   . PHE B 2 759 ? 146.380 154.037 122.875 1.00 128.79 ? 759 PHE A C   1 
ATOM 6047 O O   . PHE B 2 759 ? 146.825 153.031 123.438 1.00 130.99 ? 759 PHE A O   1 
ATOM 6048 C CB  . PHE B 2 759 ? 148.209 155.725 122.710 1.00 125.51 ? 759 PHE A CB  1 
ATOM 6049 C CG  . PHE B 2 759 ? 149.397 156.184 121.924 1.00 124.05 ? 759 PHE A CG  1 
ATOM 6050 C CD1 . PHE B 2 759 ? 149.962 155.362 120.965 1.00 124.00 ? 759 PHE A CD1 1 
ATOM 6051 C CD2 . PHE B 2 759 ? 149.949 157.433 122.138 1.00 128.28 ? 759 PHE A CD2 1 
ATOM 6052 C CE1 . PHE B 2 759 ? 151.055 155.777 120.234 1.00 128.54 ? 759 PHE A CE1 1 
ATOM 6053 C CE2 . PHE B 2 759 ? 151.042 157.853 121.410 1.00 126.50 ? 759 PHE A CE2 1 
ATOM 6054 C CZ  . PHE B 2 759 ? 151.595 157.025 120.457 1.00 128.73 ? 759 PHE A CZ  1 
ATOM 6055 N N   . PHE B 2 760 ? 145.138 154.477 123.074 1.00 138.21 ? 760 PHE A N   1 
ATOM 6056 C CA  . PHE B 2 760 ? 144.224 153.709 123.907 1.00 138.93 ? 760 PHE A CA  1 
ATOM 6057 C C   . PHE B 2 760 ? 143.686 152.479 123.190 1.00 140.81 ? 760 PHE A C   1 
ATOM 6058 O O   . PHE B 2 760 ? 143.410 151.468 123.845 1.00 139.00 ? 760 PHE A O   1 
ATOM 6059 C CB  . PHE B 2 760 ? 143.054 154.576 124.369 1.00 141.45 ? 760 PHE A CB  1 
ATOM 6060 C CG  . PHE B 2 760 ? 142.019 153.815 125.146 1.00 143.92 ? 760 PHE A CG  1 
ATOM 6061 C CD1 . PHE B 2 760 ? 142.316 153.305 126.398 1.00 144.56 ? 760 PHE A CD1 1 
ATOM 6062 C CD2 . PHE B 2 760 ? 140.765 153.578 124.612 1.00 143.39 ? 760 PHE A CD2 1 
ATOM 6063 C CE1 . PHE B 2 760 ? 141.373 152.595 127.114 1.00 144.48 ? 760 PHE A CE1 1 
ATOM 6064 C CE2 . PHE B 2 760 ? 139.818 152.868 125.323 1.00 142.50 ? 760 PHE A CE2 1 
ATOM 6065 C CZ  . PHE B 2 760 ? 140.123 152.374 126.575 1.00 143.00 ? 760 PHE A CZ  1 
ATOM 6066 N N   . CYS B 2 761 ? 143.516 152.541 121.865 1.00 150.24 ? 761 CYS A N   1 
ATOM 6067 C CA  . CYS B 2 761 ? 142.942 151.394 121.154 1.00 150.87 ? 761 CYS A CA  1 
ATOM 6068 C C   . CYS B 2 761 ? 143.670 150.079 121.413 1.00 150.82 ? 761 CYS A C   1 
ATOM 6069 O O   . CYS B 2 761 ? 142.990 149.076 121.683 1.00 150.27 ? 761 CYS A O   1 
ATOM 6070 C CB  . CYS B 2 761 ? 142.866 151.621 119.635 1.00 153.40 ? 761 CYS A CB  1 
ATOM 6071 S SG  . CYS B 2 761 ? 142.602 153.282 119.020 1.00 161.75 ? 761 CYS A SG  1 
ATOM 6072 N N   . PRO B 2 762 ? 145.005 149.988 121.323 1.00 150.87 ? 762 PRO A N   1 
ATOM 6073 C CA  . PRO B 2 762 ? 145.645 148.677 121.535 1.00 151.50 ? 762 PRO A CA  1 
ATOM 6074 C C   . PRO B 2 762 ? 145.387 148.082 122.909 1.00 151.70 ? 762 PRO A C   1 
ATOM 6075 O O   . PRO B 2 762 ? 145.182 146.866 123.023 1.00 150.88 ? 762 PRO A O   1 
ATOM 6076 C CB  . PRO B 2 762 ? 147.134 148.977 121.317 1.00 148.48 ? 762 PRO A CB  1 
ATOM 6077 C CG  . PRO B 2 762 ? 147.153 150.200 120.477 1.00 147.44 ? 762 PRO A CG  1 
ATOM 6078 C CD  . PRO B 2 762 ? 145.997 151.013 120.954 1.00 148.62 ? 762 PRO A CD  1 
ATOM 6079 N N   . VAL B 2 763 ? 145.382 148.906 123.958 1.00 153.00 ? 763 VAL A N   1 
ATOM 6080 C CA  . VAL B 2 763 ? 145.176 148.389 125.307 1.00 152.12 ? 763 VAL A CA  1 
ATOM 6081 C C   . VAL B 2 763 ? 143.776 147.807 125.444 1.00 151.91 ? 763 VAL A C   1 
ATOM 6082 O O   . VAL B 2 763 ? 143.591 146.704 125.971 1.00 151.17 ? 763 VAL A O   1 
ATOM 6083 C CB  . VAL B 2 763 ? 145.434 149.489 126.351 1.00 149.78 ? 763 VAL A CB  1 
ATOM 6084 C CG1 . VAL B 2 763 ? 145.697 148.872 127.713 1.00 148.86 ? 763 VAL A CG1 1 
ATOM 6085 C CG2 . VAL B 2 763 ? 146.599 150.362 125.922 1.00 149.01 ? 763 VAL A CG2 1 
ATOM 6086 N N   . ALA B 2 764 ? 142.769 148.539 124.964 1.00 160.68 ? 764 ALA A N   1 
ATOM 6087 C CA  . ALA B 2 764 ? 141.401 148.037 125.008 1.00 160.67 ? 764 ALA A CA  1 
ATOM 6088 C C   . ALA B 2 764 ? 141.252 146.772 124.174 1.00 163.22 ? 764 ALA A C   1 
ATOM 6089 O O   . ALA B 2 764 ? 140.603 145.807 124.598 1.00 164.25 ? 764 ALA A O   1 
ATOM 6090 C CB  . ALA B 2 764 ? 140.436 149.116 124.522 1.00 159.80 ? 764 ALA A CB  1 
ATOM 6091 N N   . PHE B 2 765 ? 141.854 146.760 122.982 1.00 174.77 ? 765 PHE A N   1 
ATOM 6092 C CA  . PHE B 2 765 ? 141.742 145.603 122.102 1.00 174.96 ? 765 PHE A CA  1 
ATOM 6093 C C   . PHE B 2 765 ? 142.342 144.362 122.744 1.00 174.06 ? 765 PHE A C   1 
ATOM 6094 O O   . PHE B 2 765 ? 141.741 143.283 122.707 1.00 172.46 ? 765 PHE A O   1 
ATOM 6095 C CB  . PHE B 2 765 ? 142.420 145.897 120.765 1.00 176.94 ? 765 PHE A CB  1 
ATOM 6096 C CG  . PHE B 2 765 ? 142.210 144.830 119.729 1.00 178.10 ? 765 PHE A CG  1 
ATOM 6097 C CD1 . PHE B 2 765 ? 141.031 144.103 119.691 1.00 176.13 ? 765 PHE A CD1 1 
ATOM 6098 C CD2 . PHE B 2 765 ? 143.190 144.557 118.790 1.00 176.22 ? 765 PHE A CD2 1 
ATOM 6099 C CE1 . PHE B 2 765 ? 140.836 143.121 118.738 1.00 175.94 ? 765 PHE A CE1 1 
ATOM 6100 C CE2 . PHE B 2 765 ? 143.001 143.577 117.834 1.00 175.65 ? 765 PHE A CE2 1 
ATOM 6101 C CZ  . PHE B 2 765 ? 141.823 142.858 117.808 1.00 176.82 ? 765 PHE A CZ  1 
ATOM 6102 N N   . PHE B 2 766 ? 143.519 144.492 123.354 1.00 172.26 ? 766 PHE A N   1 
ATOM 6103 C CA  . PHE B 2 766 ? 144.160 143.324 123.943 1.00 171.81 ? 766 PHE A CA  1 
ATOM 6104 C C   . PHE B 2 766 ? 143.635 142.996 125.333 1.00 171.51 ? 766 PHE A C   1 
ATOM 6105 O O   . PHE B 2 766 ? 143.937 141.914 125.847 1.00 170.41 ? 766 PHE A O   1 
ATOM 6106 C CB  . PHE B 2 766 ? 145.679 143.508 123.981 1.00 169.16 ? 766 PHE A CB  1 
ATOM 6107 C CG  . PHE B 2 766 ? 146.333 143.440 122.625 1.00 172.60 ? 766 PHE A CG  1 
ATOM 6108 C CD1 . PHE B 2 766 ? 145.574 143.451 121.464 1.00 175.36 ? 766 PHE A CD1 1 
ATOM 6109 C CD2 . PHE B 2 766 ? 147.705 143.338 122.512 1.00 172.24 ? 766 PHE A CD2 1 
ATOM 6110 C CE1 . PHE B 2 766 ? 146.175 143.384 120.222 1.00 174.26 ? 766 PHE A CE1 1 
ATOM 6111 C CE2 . PHE B 2 766 ? 148.313 143.269 121.272 1.00 174.16 ? 766 PHE A CE2 1 
ATOM 6112 C CZ  . PHE B 2 766 ? 147.546 143.291 120.126 1.00 173.97 ? 766 PHE A CZ  1 
ATOM 6113 N N   . SER B 2 767 ? 142.873 143.894 125.956 1.00 179.13 ? 767 SER A N   1 
ATOM 6114 C CA  . SER B 2 767 ? 142.109 143.503 127.133 1.00 179.66 ? 767 SER A CA  1 
ATOM 6115 C C   . SER B 2 767 ? 140.866 142.716 126.738 1.00 181.66 ? 767 SER A C   1 
ATOM 6116 O O   . SER B 2 767 ? 140.469 141.780 127.441 1.00 182.43 ? 767 SER A O   1 
ATOM 6117 C CB  . SER B 2 767 ? 141.725 144.736 127.950 1.00 178.76 ? 767 SER A CB  1 
ATOM 6118 O OG  . SER B 2 767 ? 140.957 145.638 127.173 1.00 178.34 ? 767 SER A OG  1 
ATOM 6119 N N   . PHE B 2 768 ? 140.241 143.086 125.618 1.00 194.72 ? 768 PHE A N   1 
ATOM 6120 C CA  . PHE B 2 768 ? 139.060 142.373 125.143 1.00 195.56 ? 768 PHE A CA  1 
ATOM 6121 C C   . PHE B 2 768 ? 139.408 141.042 124.486 1.00 196.05 ? 768 PHE A C   1 
ATOM 6122 O O   . PHE B 2 768 ? 138.579 140.124 124.485 1.00 194.91 ? 768 PHE A O   1 
ATOM 6123 C CB  . PHE B 2 768 ? 138.282 143.246 124.157 1.00 194.64 ? 768 PHE A CB  1 
ATOM 6124 C CG  . PHE B 2 768 ? 137.124 143.975 124.774 1.00 193.99 ? 768 PHE A CG  1 
ATOM 6125 C CD1 . PHE B 2 768 ? 136.979 144.038 126.150 1.00 193.84 ? 768 PHE A CD1 1 
ATOM 6126 C CD2 . PHE B 2 768 ? 136.177 144.597 123.977 1.00 191.58 ? 768 PHE A CD2 1 
ATOM 6127 C CE1 . PHE B 2 768 ? 135.913 144.707 126.719 1.00 193.88 ? 768 PHE A CE1 1 
ATOM 6128 C CE2 . PHE B 2 768 ? 135.109 145.269 124.540 1.00 191.82 ? 768 PHE A CE2 1 
ATOM 6129 C CZ  . PHE B 2 768 ? 134.977 145.324 125.913 1.00 193.71 ? 768 PHE A CZ  1 
ATOM 6130 N N   . ALA B 2 769 ? 140.610 140.924 123.919 1.00 197.79 ? 769 ALA A N   1 
ATOM 6131 C CA  . ALA B 2 769 ? 140.970 139.727 123.160 1.00 196.41 ? 769 ALA A CA  1 
ATOM 6132 C C   . ALA B 2 769 ? 140.879 138.433 123.962 1.00 196.67 ? 769 ALA A C   1 
ATOM 6133 O O   . ALA B 2 769 ? 140.293 137.464 123.450 1.00 196.37 ? 769 ALA A O   1 
ATOM 6134 C CB  . ALA B 2 769 ? 142.368 139.908 122.557 1.00 195.21 ? 769 ALA A CB  1 
ATOM 6135 N N   . PRO B 2 770 ? 141.422 138.325 125.181 1.00 193.86 ? 770 PRO A N   1 
ATOM 6136 C CA  . PRO B 2 770 ? 141.329 137.041 125.898 1.00 193.55 ? 770 PRO A CA  1 
ATOM 6137 C C   . PRO B 2 770 ? 139.905 136.606 126.190 1.00 194.59 ? 770 PRO A C   1 
ATOM 6138 O O   . PRO B 2 770 ? 139.667 135.405 126.370 1.00 192.56 ? 770 PRO A O   1 
ATOM 6139 C CB  . PRO B 2 770 ? 142.113 137.298 127.193 1.00 193.30 ? 770 PRO A CB  1 
ATOM 6140 C CG  . PRO B 2 770 ? 142.104 138.770 127.357 1.00 193.35 ? 770 PRO A CG  1 
ATOM 6141 C CD  . PRO B 2 770 ? 142.162 139.325 125.973 1.00 192.83 ? 770 PRO A CD  1 
ATOM 6142 N N   . LEU B 2 771 ? 138.953 137.540 126.249 1.00 199.68 ? 771 LEU A N   1 
ATOM 6143 C CA  . LEU B 2 771 ? 137.558 137.160 126.440 1.00 199.07 ? 771 LEU A CA  1 
ATOM 6144 C C   . LEU B 2 771 ? 137.047 136.335 125.265 1.00 200.46 ? 771 LEU A C   1 
ATOM 6145 O O   . LEU B 2 771 ? 136.317 135.355 125.454 1.00 199.06 ? 771 LEU A O   1 
ATOM 6146 C CB  . LEU B 2 771 ? 136.698 138.407 126.638 1.00 198.14 ? 771 LEU A CB  1 
ATOM 6147 C CG  . LEU B 2 771 ? 137.283 139.480 127.558 1.00 197.14 ? 771 LEU A CG  1 
ATOM 6148 C CD1 . LEU B 2 771 ? 136.435 140.741 127.522 1.00 196.29 ? 771 LEU A CD1 1 
ATOM 6149 C CD2 . LEU B 2 771 ? 137.408 138.954 128.980 1.00 197.48 ? 771 LEU A CD2 1 
ATOM 6150 N N   . ILE B 2 772 ? 137.420 136.714 124.047 1.00 211.36 ? 772 ILE A N   1 
ATOM 6151 C CA  . ILE B 2 772 ? 137.021 135.989 122.846 1.00 211.04 ? 772 ILE A CA  1 
ATOM 6152 C C   . ILE B 2 772 ? 138.009 134.853 122.617 1.00 211.58 ? 772 ILE A C   1 
ATOM 6153 O O   . ILE B 2 772 ? 139.209 135.089 122.435 1.00 210.22 ? 772 ILE A O   1 
ATOM 6154 C CB  . ILE B 2 772 ? 136.958 136.921 121.628 1.00 208.60 ? 772 ILE A CB  1 
ATOM 6155 C CG1 . ILE B 2 772 ? 135.934 138.034 121.860 1.00 207.29 ? 772 ILE A CG1 1 
ATOM 6156 C CG2 . ILE B 2 772 ? 136.619 136.133 120.372 1.00 208.22 ? 772 ILE A CG2 1 
ATOM 6157 C CD1 . ILE B 2 772 ? 136.305 139.350 121.213 1.00 206.67 ? 772 ILE A CD1 1 
ATOM 6158 N N   . THR B 2 773 ? 137.505 133.618 122.621 1.00 219.83 ? 773 THR A N   1 
ATOM 6159 C CA  . THR B 2 773 ? 138.370 132.458 122.437 1.00 218.61 ? 773 THR A CA  1 
ATOM 6160 C C   . THR B 2 773 ? 138.849 132.309 121.000 1.00 218.11 ? 773 THR A C   1 
ATOM 6161 O O   . THR B 2 773 ? 139.806 131.568 120.754 1.00 217.81 ? 773 THR A O   1 
ATOM 6162 C CB  . THR B 2 773 ? 137.644 131.184 122.872 1.00 217.64 ? 773 THR A CB  1 
ATOM 6163 O OG1 . THR B 2 773 ? 136.818 130.713 121.799 1.00 217.43 ? 773 THR A OG1 1 
ATOM 6164 C CG2 . THR B 2 773 ? 136.776 131.455 124.091 1.00 216.98 ? 773 THR A CG2 1 
ATOM 6165 N N   . ALA B 2 774 ? 138.203 132.988 120.048 1.00 209.39 ? 774 ALA A N   1 
ATOM 6166 C CA  . ALA B 2 774 ? 138.606 132.870 118.650 1.00 207.85 ? 774 ALA A CA  1 
ATOM 6167 C C   . ALA B 2 774 ? 140.008 133.423 118.425 1.00 209.18 ? 774 ALA A C   1 
ATOM 6168 O O   . ALA B 2 774 ? 140.802 132.834 117.683 1.00 208.84 ? 774 ALA A O   1 
ATOM 6169 C CB  . ALA B 2 774 ? 137.597 133.583 117.751 1.00 206.63 ? 774 ALA A CB  1 
ATOM 6170 N N   . ILE B 2 775 ? 140.331 134.547 119.055 1.00 206.86 ? 775 ILE A N   1 
ATOM 6171 C CA  . ILE B 2 775 ? 141.621 135.201 118.869 1.00 206.02 ? 775 ILE A CA  1 
ATOM 6172 C C   . ILE B 2 775 ? 142.585 134.709 119.939 1.00 204.82 ? 775 ILE A C   1 
ATOM 6173 O O   . ILE B 2 775 ? 142.274 134.747 121.136 1.00 204.51 ? 775 ILE A O   1 
ATOM 6174 C CB  . ILE B 2 775 ? 141.475 136.731 118.921 1.00 204.47 ? 775 ILE A CB  1 
ATOM 6175 C CG1 . ILE B 2 775 ? 140.137 137.163 118.315 1.00 203.19 ? 775 ILE A CG1 1 
ATOM 6176 C CG2 . ILE B 2 775 ? 142.635 137.401 118.200 1.00 202.77 ? 775 ILE A CG2 1 
ATOM 6177 C CD1 . ILE B 2 775 ? 140.066 137.006 116.810 1.00 202.22 ? 775 ILE A CD1 1 
ATOM 6178 N N   . SER B 2 776 ? 143.755 134.246 119.510 1.00 193.12 ? 776 SER A N   1 
ATOM 6179 C CA  . SER B 2 776 ? 144.807 133.787 120.408 1.00 193.19 ? 776 SER A CA  1 
ATOM 6180 C C   . SER B 2 776 ? 145.996 134.730 120.286 1.00 194.59 ? 776 SER A C   1 
ATOM 6181 O O   . SER B 2 776 ? 146.512 134.944 119.184 1.00 195.13 ? 776 SER A O   1 
ATOM 6182 C CB  . SER B 2 776 ? 145.220 132.352 120.082 1.00 191.83 ? 776 SER A CB  1 
ATOM 6183 O OG  . SER B 2 776 ? 145.771 132.264 118.779 1.00 191.78 ? 776 SER A OG  1 
ATOM 6184 N N   . ILE B 2 777 ? 146.428 135.286 121.415 1.00 175.72 ? 777 ILE A N   1 
ATOM 6185 C CA  . ILE B 2 777 ? 147.521 136.250 121.459 1.00 174.27 ? 777 ILE A CA  1 
ATOM 6186 C C   . ILE B 2 777 ? 148.548 135.765 122.471 1.00 174.72 ? 777 ILE A C   1 
ATOM 6187 O O   . ILE B 2 777 ? 148.187 135.371 123.586 1.00 173.99 ? 777 ILE A O   1 
ATOM 6188 C CB  . ILE B 2 777 ? 147.021 137.661 121.825 1.00 171.70 ? 777 ILE A CB  1 
ATOM 6189 C CG1 . ILE B 2 777 ? 146.125 138.215 120.717 1.00 172.19 ? 777 ILE A CG1 1 
ATOM 6190 C CG2 . ILE B 2 777 ? 148.191 138.598 122.072 1.00 171.51 ? 777 ILE A CG2 1 
ATOM 6191 C CD1 . ILE B 2 777 ? 146.781 138.235 119.354 1.00 172.04 ? 777 ILE A CD1 1 
ATOM 6192 N N   . SER B 2 778 ? 149.818 135.786 122.083 1.00 161.97 ? 778 SER A N   1 
ATOM 6193 C CA  . SER B 2 778 ? 150.879 135.377 122.991 1.00 160.42 ? 778 SER A CA  1 
ATOM 6194 C C   . SER B 2 778 ? 150.949 136.344 124.170 1.00 161.14 ? 778 SER A C   1 
ATOM 6195 O O   . SER B 2 778 ? 151.011 137.564 123.962 1.00 160.46 ? 778 SER A O   1 
ATOM 6196 C CB  . SER B 2 778 ? 152.222 135.331 122.264 1.00 157.59 ? 778 SER A CB  1 
ATOM 6197 O OG  . SER B 2 778 ? 152.959 136.521 122.482 1.00 157.93 ? 778 SER A OG  1 
ATOM 6198 N N   . PRO B 2 779 ? 150.931 135.849 125.409 1.00 152.68 ? 779 PRO A N   1 
ATOM 6199 C CA  . PRO B 2 779 ? 150.927 136.763 126.564 1.00 150.79 ? 779 PRO A CA  1 
ATOM 6200 C C   . PRO B 2 779 ? 152.144 137.667 126.639 1.00 150.65 ? 779 PRO A C   1 
ATOM 6201 O O   . PRO B 2 779 ? 152.026 138.801 127.117 1.00 151.89 ? 779 PRO A O   1 
ATOM 6202 C CB  . PRO B 2 779 ? 150.856 135.809 127.765 1.00 149.28 ? 779 PRO A CB  1 
ATOM 6203 C CG  . PRO B 2 779 ? 151.331 134.491 127.244 1.00 149.25 ? 779 PRO A CG  1 
ATOM 6204 C CD  . PRO B 2 779 ? 150.891 134.436 125.818 1.00 150.11 ? 779 PRO A CD  1 
ATOM 6205 N N   . GLU B 2 780 ? 153.314 137.202 126.195 1.00 148.25 ? 780 GLU A N   1 
ATOM 6206 C CA  . GLU B 2 780 ? 154.507 138.042 126.255 1.00 148.12 ? 780 GLU A CA  1 
ATOM 6207 C C   . GLU B 2 780 ? 154.363 139.271 125.365 1.00 150.96 ? 780 GLU A C   1 
ATOM 6208 O O   . GLU B 2 780 ? 154.709 140.388 125.773 1.00 153.31 ? 780 GLU A O   1 
ATOM 6209 C CB  . GLU B 2 780 ? 155.746 137.230 125.871 1.00 145.95 ? 780 GLU A CB  1 
ATOM 6210 C CG  . GLU B 2 780 ? 155.679 136.547 124.508 1.00 149.83 ? 780 GLU A CG  1 
ATOM 6211 C CD  . GLU B 2 780 ? 154.978 135.200 124.548 1.00 153.91 ? 780 GLU A CD  1 
ATOM 6212 O OE1 . GLU B 2 780 ? 154.065 135.021 125.381 1.00 152.72 ? 780 GLU A OE1 1 
ATOM 6213 O OE2 . GLU B 2 780 ? 155.341 134.318 123.741 1.00 155.11 ? 780 GLU A OE2 1 
ATOM 6214 N N   . ILE B 2 781 ? 153.839 139.090 124.152 1.00 144.21 ? 781 ILE A N   1 
ATOM 6215 C CA  . ILE B 2 781 ? 153.630 140.221 123.256 1.00 144.10 ? 781 ILE A CA  1 
ATOM 6216 C C   . ILE B 2 781 ? 152.581 141.165 123.829 1.00 141.95 ? 781 ILE A C   1 
ATOM 6217 O O   . ILE B 2 781 ? 152.711 142.391 123.736 1.00 141.59 ? 781 ILE A O   1 
ATOM 6218 C CB  . ILE B 2 781 ? 153.247 139.721 121.850 1.00 143.86 ? 781 ILE A CB  1 
ATOM 6219 C CG1 . ILE B 2 781 ? 154.497 139.278 121.086 1.00 141.68 ? 781 ILE A CG1 1 
ATOM 6220 C CG2 . ILE B 2 781 ? 152.500 140.794 121.072 1.00 142.58 ? 781 ILE A CG2 1 
ATOM 6221 C CD1 . ILE B 2 781 ? 155.578 140.335 121.014 1.00 135.13 ? 781 ILE A CD1 1 
ATOM 6222 N N   . MET B 2 782 ? 151.529 140.610 124.434 1.00 138.06 ? 782 MET A N   1 
ATOM 6223 C CA  . MET B 2 782 ? 150.500 141.441 125.050 1.00 138.38 ? 782 MET A CA  1 
ATOM 6224 C C   . MET B 2 782 ? 151.083 142.296 126.168 1.00 138.19 ? 782 MET A C   1 
ATOM 6225 O O   . MET B 2 782 ? 150.809 143.498 126.257 1.00 137.82 ? 782 MET A O   1 
ATOM 6226 C CB  . MET B 2 782 ? 149.370 140.558 125.579 1.00 137.37 ? 782 MET A CB  1 
ATOM 6227 C CG  . MET B 2 782 ? 148.317 141.303 126.377 1.00 141.37 ? 782 MET A CG  1 
ATOM 6228 S SD  . MET B 2 782 ? 146.730 140.449 126.392 1.00 150.55 ? 782 MET A SD  1 
ATOM 6229 C CE  . MET B 2 782 ? 147.263 138.740 126.363 1.00 141.43 ? 782 MET A CE  1 
ATOM 6230 N N   . LYS B 2 783 ? 151.904 141.691 127.028 1.00 117.29 ? 783 LYS A N   1 
ATOM 6231 C CA  . LYS B 2 783 ? 152.521 142.447 128.111 1.00 113.36 ? 783 LYS A CA  1 
ATOM 6232 C C   . LYS B 2 783 ? 153.465 143.513 127.571 1.00 115.46 ? 783 LYS A C   1 
ATOM 6233 O O   . LYS B 2 783 ? 153.479 144.649 128.063 1.00 119.43 ? 783 LYS A O   1 
ATOM 6234 C CB  . LYS B 2 783 ? 153.258 141.497 129.054 1.00 111.81 ? 783 LYS A CB  1 
ATOM 6235 C CG  . LYS B 2 783 ? 154.497 142.089 129.694 1.00 111.00 ? 783 LYS A CG  1 
ATOM 6236 C CD  . LYS B 2 783 ? 154.970 141.240 130.857 1.00 113.37 ? 783 LYS A CD  1 
ATOM 6237 C CE  . LYS B 2 783 ? 156.474 141.323 131.008 1.00 112.85 ? 783 LYS A CE  1 
ATOM 6238 N NZ  . LYS B 2 783 ? 157.009 140.209 131.834 1.00 115.77 ? 783 LYS A NZ  1 
ATOM 6239 N N   . SER B 2 784 ? 154.256 143.170 126.550 1.00 116.02 ? 784 SER A N   1 
ATOM 6240 C CA  . SER B 2 784 ? 155.187 144.140 125.984 1.00 116.93 ? 784 SER A CA  1 
ATOM 6241 C C   . SER B 2 784 ? 154.451 145.326 125.375 1.00 120.15 ? 784 SER A C   1 
ATOM 6242 O O   . SER B 2 784 ? 154.832 146.482 125.592 1.00 119.63 ? 784 SER A O   1 
ATOM 6243 C CB  . SER B 2 784 ? 156.075 143.465 124.940 1.00 114.31 ? 784 SER A CB  1 
ATOM 6244 O OG  . SER B 2 784 ? 156.464 142.171 125.363 1.00 117.38 ? 784 SER A OG  1 
ATOM 6245 N N   . VAL B 2 785 ? 153.383 145.063 124.621 1.00 117.97 ? 785 VAL A N   1 
ATOM 6246 C CA  . VAL B 2 785 ? 152.652 146.150 123.979 1.00 114.24 ? 785 VAL A CA  1 
ATOM 6247 C C   . VAL B 2 785 ? 151.905 146.984 125.016 1.00 115.82 ? 785 VAL A C   1 
ATOM 6248 O O   . VAL B 2 785 ? 151.777 148.208 124.870 1.00 115.77 ? 785 VAL A O   1 
ATOM 6249 C CB  . VAL B 2 785 ? 151.717 145.595 122.887 1.00 114.98 ? 785 VAL A CB  1 
ATOM 6250 C CG1 . VAL B 2 785 ? 150.573 144.822 123.491 1.00 116.97 ? 785 VAL A CG1 1 
ATOM 6251 C CG2 . VAL B 2 785 ? 151.196 146.712 122.009 1.00 114.29 ? 785 VAL A CG2 1 
ATOM 6252 N N   . THR B 2 786 ? 151.404 146.347 126.080 1.00 111.34 ? 786 THR A N   1 
ATOM 6253 C CA  . THR B 2 786 ? 150.768 147.100 127.155 1.00 108.90 ? 786 THR A CA  1 
ATOM 6254 C C   . THR B 2 786 ? 151.765 148.035 127.823 1.00 108.56 ? 786 THR A C   1 
ATOM 6255 O O   . THR B 2 786 ? 151.471 149.212 128.060 1.00 114.91 ? 786 THR A O   1 
ATOM 6256 C CB  . THR B 2 786 ? 150.161 146.144 128.182 1.00 105.76 ? 786 THR A CB  1 
ATOM 6257 O OG1 . THR B 2 786 ? 149.547 145.041 127.507 1.00 112.59 ? 786 THR A OG1 1 
ATOM 6258 C CG2 . THR B 2 786 ? 149.120 146.861 129.023 1.00 105.32 ? 786 THR A CG2 1 
ATOM 6259 N N   . LEU B 2 787 ? 152.969 147.520 128.093 1.00 94.32  ? 787 LEU A N   1 
ATOM 6260 C CA  . LEU B 2 787 ? 154.039 148.325 128.728 1.00 92.11  ? 787 LEU A CA  1 
ATOM 6261 C C   . LEU B 2 787 ? 154.451 149.446 127.762 1.00 94.71  ? 787 LEU A C   1 
ATOM 6262 O O   . LEU B 2 787 ? 154.834 150.522 128.262 1.00 92.61  ? 787 LEU A O   1 
ATOM 6263 C CB  . LEU B 2 787 ? 155.214 147.416 129.079 1.00 93.62  ? 787 LEU A CB  1 
ATOM 6264 C CG  . LEU B 2 787 ? 155.095 146.642 130.395 1.00 94.11  ? 787 LEU A CG  1 
ATOM 6265 C CD1 . LEU B 2 787 ? 155.826 145.315 130.342 1.00 96.45  ? 787 LEU A CD1 1 
ATOM 6266 C CD2 . LEU B 2 787 ? 155.618 147.473 131.547 1.00 95.61  ? 787 LEU A CD2 1 
ATOM 6267 N N   . ILE B 2 788 ? 154.382 149.218 126.442 1.00 105.92 ? 788 ILE A N   1 
ATOM 6268 C CA  . ILE B 2 788 ? 154.798 150.223 125.470 1.00 105.23 ? 788 ILE A CA  1 
ATOM 6269 C C   . ILE B 2 788 ? 153.782 151.357 125.392 1.00 106.97 ? 788 ILE A C   1 
ATOM 6270 O O   . ILE B 2 788 ? 154.144 152.538 125.445 1.00 107.59 ? 788 ILE A O   1 
ATOM 6271 C CB  . ILE B 2 788 ? 155.018 149.573 124.093 1.00 109.08 ? 788 ILE A CB  1 
ATOM 6272 C CG1 . ILE B 2 788 ? 156.389 148.903 124.036 1.00 107.94 ? 788 ILE A CG1 1 
ATOM 6273 C CG2 . ILE B 2 788 ? 154.892 150.607 122.986 1.00 108.39 ? 788 ILE A CG2 1 
ATOM 6274 C CD1 . ILE B 2 788 ? 157.514 149.874 123.815 1.00 104.34 ? 788 ILE A CD1 1 
ATOM 6275 N N   . PHE B 2 789 ? 152.496 151.022 125.273 1.00 108.99 ? 789 PHE A N   1 
ATOM 6276 C CA  . PHE B 2 789 ? 151.498 152.024 124.918 1.00 105.12 ? 789 PHE A CA  1 
ATOM 6277 C C   . PHE B 2 789 ? 150.669 152.562 126.076 1.00 108.77 ? 789 PHE A C   1 
ATOM 6278 O O   . PHE B 2 789 ? 150.004 153.587 125.901 1.00 115.71 ? 789 PHE A O   1 
ATOM 6279 C CB  . PHE B 2 789 ? 150.551 151.480 123.844 1.00 107.03 ? 789 PHE A CB  1 
ATOM 6280 C CG  . PHE B 2 789 ? 151.204 151.289 122.510 1.00 113.47 ? 789 PHE A CG  1 
ATOM 6281 C CD1 . PHE B 2 789 ? 151.955 152.305 121.948 1.00 112.47 ? 789 PHE A CD1 1 
ATOM 6282 C CD2 . PHE B 2 789 ? 151.063 150.106 121.814 1.00 115.02 ? 789 PHE A CD2 1 
ATOM 6283 C CE1 . PHE B 2 789 ? 152.560 152.142 120.719 1.00 111.50 ? 789 PHE A CE1 1 
ATOM 6284 C CE2 . PHE B 2 789 ? 151.666 149.935 120.583 1.00 118.10 ? 789 PHE A CE2 1 
ATOM 6285 C CZ  . PHE B 2 789 ? 152.415 150.956 120.035 1.00 114.45 ? 789 PHE A CZ  1 
ATOM 6286 N N   . PHE B 2 790 ? 150.674 151.923 127.238 1.00 88.15  ? 790 PHE A N   1 
ATOM 6287 C CA  . PHE B 2 790 ? 149.929 152.492 128.383 1.00 75.10  ? 790 PHE A CA  1 
ATOM 6288 C C   . PHE B 2 790 ? 150.536 153.819 128.687 1.00 77.68  ? 790 PHE A C   1 
ATOM 6289 O O   . PHE B 2 790 ? 149.768 154.764 128.640 1.00 90.20  ? 790 PHE A O   1 
ATOM 6290 C CB  . PHE B 2 790 ? 149.919 151.690 129.675 1.00 77.18  ? 790 PHE A CB  1 
ATOM 6291 C CG  . PHE B 2 790 ? 148.696 151.905 130.543 1.00 77.90  ? 790 PHE A CG  1 
ATOM 6292 C CD1 . PHE B 2 790 ? 147.437 151.554 130.088 1.00 86.77  ? 790 PHE A CD1 1 
ATOM 6293 C CD2 . PHE B 2 790 ? 148.815 152.437 131.813 1.00 81.74  ? 790 PHE A CD2 1 
ATOM 6294 C CE1 . PHE B 2 790 ? 146.325 151.754 130.880 1.00 90.05  ? 790 PHE A CE1 1 
ATOM 6295 C CE2 . PHE B 2 790 ? 147.698 152.626 132.601 1.00 84.57  ? 790 PHE A CE2 1 
ATOM 6296 C CZ  . PHE B 2 790 ? 146.459 152.286 132.135 1.00 88.81  ? 790 PHE A CZ  1 
ATOM 6297 N N   . PRO B 2 791 ? 151.834 153.979 128.994 1.00 75.52  ? 791 PRO A N   1 
ATOM 6298 C CA  . PRO B 2 791 ? 152.375 155.280 129.402 1.00 79.44  ? 791 PRO A CA  1 
ATOM 6299 C C   . PRO B 2 791 ? 152.779 156.190 128.253 1.00 81.08  ? 791 PRO A C   1 
ATOM 6300 O O   . PRO B 2 791 ? 153.199 157.323 128.514 1.00 86.18  ? 791 PRO A O   1 
ATOM 6301 C CB  . PRO B 2 791 ? 153.613 154.904 130.240 1.00 84.80  ? 791 PRO A CB  1 
ATOM 6302 C CG  . PRO B 2 791 ? 153.711 153.392 130.202 1.00 84.98  ? 791 PRO A CG  1 
ATOM 6303 C CD  . PRO B 2 791 ? 152.913 152.961 129.034 1.00 83.68  ? 791 PRO A CD  1 
ATOM 6304 N N   . LEU B 2 792 ? 152.677 155.730 127.008 1.00 93.49  ? 792 LEU A N   1 
ATOM 6305 C CA  . LEU B 2 792 ? 153.144 156.533 125.880 1.00 95.90  ? 792 LEU A CA  1 
ATOM 6306 C C   . LEU B 2 792 ? 152.469 157.896 125.754 1.00 99.34  ? 792 LEU A C   1 
ATOM 6307 O O   . LEU B 2 792 ? 153.177 158.868 125.438 1.00 98.70  ? 792 LEU A O   1 
ATOM 6308 C CB  . LEU B 2 792 ? 152.995 155.736 124.579 1.00 99.29  ? 792 LEU A CB  1 
ATOM 6309 C CG  . LEU B 2 792 ? 153.877 156.231 123.432 1.00 100.05 ? 792 LEU A CG  1 
ATOM 6310 C CD1 . LEU B 2 792 ? 155.269 156.574 123.932 1.00 96.04  ? 792 LEU A CD1 1 
ATOM 6311 C CD2 . LEU B 2 792 ? 153.953 155.191 122.332 1.00 104.57 ? 792 LEU A CD2 1 
ATOM 6312 N N   . PRO B 2 793 ? 151.149 158.048 125.939 1.00 89.79  ? 793 PRO A N   1 
ATOM 6313 C CA  . PRO B 2 793 ? 150.569 159.400 125.845 1.00 87.80  ? 793 PRO A CA  1 
ATOM 6314 C C   . PRO B 2 793 ? 151.198 160.388 126.807 1.00 90.23  ? 793 PRO A C   1 
ATOM 6315 O O   . PRO B 2 793 ? 151.349 161.571 126.472 1.00 99.53  ? 793 PRO A O   1 
ATOM 6316 C CB  . PRO B 2 793 ? 149.087 159.163 126.158 1.00 91.54  ? 793 PRO A CB  1 
ATOM 6317 C CG  . PRO B 2 793 ? 148.846 157.761 125.767 1.00 87.58  ? 793 PRO A CG  1 
ATOM 6318 C CD  . PRO B 2 793 ? 150.102 157.024 126.106 1.00 86.73  ? 793 PRO A CD  1 
ATOM 6319 N N   . ALA B 2 794 ? 151.571 159.930 128.003 1.00 90.01  ? 794 ALA A N   1 
ATOM 6320 C CA  . ALA B 2 794 ? 152.268 160.796 128.945 1.00 90.75  ? 794 ALA A CA  1 
ATOM 6321 C C   . ALA B 2 794 ? 153.619 161.227 128.396 1.00 92.71  ? 794 ALA A C   1 
ATOM 6322 O O   . ALA B 2 794 ? 154.067 162.352 128.640 1.00 96.57  ? 794 ALA A O   1 
ATOM 6323 C CB  . ALA B 2 794 ? 152.437 160.085 130.285 1.00 91.32  ? 794 ALA A CB  1 
ATOM 6324 N N   . CYS B 2 795 ? 154.292 160.334 127.671 1.00 106.14 ? 795 CYS A N   1 
ATOM 6325 C CA  . CYS B 2 795 ? 155.550 160.692 127.029 1.00 107.64 ? 795 CYS A CA  1 
ATOM 6326 C C   . CYS B 2 795 ? 155.342 161.670 125.881 1.00 108.86 ? 795 CYS A C   1 
ATOM 6327 O O   . CYS B 2 795 ? 156.200 162.525 125.635 1.00 115.64 ? 795 CYS A O   1 
ATOM 6328 C CB  . CYS B 2 795 ? 156.251 159.429 126.530 1.00 112.76 ? 795 CYS A CB  1 
ATOM 6329 S SG  . CYS B 2 795 ? 157.379 159.679 125.143 1.00 130.78 ? 795 CYS A SG  1 
ATOM 6330 N N   . LEU B 2 796 ? 154.217 161.572 125.179 1.00 100.60 ? 796 LEU A N   1 
ATOM 6331 C CA  . LEU B 2 796 ? 154.043 162.276 123.914 1.00 103.21 ? 796 LEU A CA  1 
ATOM 6332 C C   . LEU B 2 796 ? 153.427 163.662 124.059 1.00 104.35 ? 796 LEU A C   1 
ATOM 6333 O O   . LEU B 2 796 ? 153.885 164.598 123.398 1.00 101.05 ? 796 LEU A O   1 
ATOM 6334 C CB  . LEU B 2 796 ? 153.184 161.441 122.961 1.00 106.81 ? 796 LEU A CB  1 
ATOM 6335 C CG  . LEU B 2 796 ? 153.194 161.913 121.508 1.00 109.90 ? 796 LEU A CG  1 
ATOM 6336 C CD1 . LEU B 2 796 ? 154.612 162.250 121.079 1.00 110.31 ? 796 LEU A CD1 1 
ATOM 6337 C CD2 . LEU B 2 796 ? 152.594 160.862 120.594 1.00 105.88 ? 796 LEU A CD2 1 
ATOM 6338 N N   . ASN B 2 797 ? 152.395 163.817 124.892 1.00 105.45 ? 797 ASN A N   1 
ATOM 6339 C CA  . ASN B 2 797 ? 151.688 165.097 124.970 1.00 99.26  ? 797 ASN A CA  1 
ATOM 6340 C C   . ASN B 2 797 ? 152.525 166.347 125.223 1.00 98.43  ? 797 ASN A C   1 
ATOM 6341 O O   . ASN B 2 797 ? 152.396 167.318 124.451 1.00 105.72 ? 797 ASN A O   1 
ATOM 6342 C CB  . ASN B 2 797 ? 150.565 165.014 126.009 1.00 98.85  ? 797 ASN A CB  1 
ATOM 6343 C CG  . ASN B 2 797 ? 149.531 163.961 125.667 1.00 105.65 ? 797 ASN A CG  1 
ATOM 6344 O OD1 . ASN B 2 797 ? 148.823 163.464 126.542 1.00 108.57 ? 797 ASN A OD1 1 
ATOM 6345 N ND2 . ASN B 2 797 ? 149.438 163.616 124.389 1.00 102.00 ? 797 ASN A ND2 1 
ATOM 6346 N N   . PRO B 2 798 ? 153.395 166.355 126.247 1.00 98.46  ? 798 PRO A N   1 
ATOM 6347 C CA  . PRO B 2 798 ? 154.201 167.528 126.444 1.00 103.50 ? 798 PRO A CA  1 
ATOM 6348 C C   . PRO B 2 798 ? 155.243 167.745 125.359 1.00 109.49 ? 798 PRO A C   1 
ATOM 6349 O O   . PRO B 2 798 ? 155.713 168.852 125.280 1.00 112.81 ? 798 PRO A O   1 
ATOM 6350 C CB  . PRO B 2 798 ? 154.913 167.219 127.722 1.00 104.35 ? 798 PRO A CB  1 
ATOM 6351 C CG  . PRO B 2 798 ? 155.047 165.742 127.717 1.00 108.00 ? 798 PRO A CG  1 
ATOM 6352 C CD  . PRO B 2 798 ? 153.736 165.337 127.106 1.00 103.86 ? 798 PRO A CD  1 
ATOM 6353 N N   . VAL B 2 799 ? 155.594 166.733 124.572 1.00 114.73 ? 799 VAL A N   1 
ATOM 6354 C CA  . VAL B 2 799 ? 156.512 166.858 123.442 1.00 111.51 ? 799 VAL A CA  1 
ATOM 6355 C C   . VAL B 2 799 ? 155.781 167.743 122.440 1.00 114.93 ? 799 VAL A C   1 
ATOM 6356 O O   . VAL B 2 799 ? 156.331 168.729 121.930 1.00 119.00 ? 799 VAL A O   1 
ATOM 6357 C CB  . VAL B 2 799 ? 156.937 165.520 122.809 1.00 114.86 ? 799 VAL A CB  1 
ATOM 6358 C CG1 . VAL B 2 799 ? 157.183 165.681 121.318 1.00 119.53 ? 799 VAL A CG1 1 
ATOM 6359 C CG2 . VAL B 2 799 ? 158.169 164.968 123.500 1.00 115.24 ? 799 VAL A CG2 1 
ATOM 6360 N N   . LEU B 2 800 ? 154.521 167.408 122.151 1.00 108.34 ? 800 LEU A N   1 
ATOM 6361 C CA  . LEU B 2 800 ? 153.739 168.207 121.215 1.00 107.77 ? 800 LEU A CA  1 
ATOM 6362 C C   . LEU B 2 800 ? 153.518 169.616 121.742 1.00 112.55 ? 800 LEU A C   1 
ATOM 6363 O O   . LEU B 2 800 ? 153.586 170.586 120.980 1.00 113.87 ? 800 LEU A O   1 
ATOM 6364 C CB  . LEU B 2 800 ? 152.402 167.527 120.918 1.00 108.24 ? 800 LEU A CB  1 
ATOM 6365 C CG  . LEU B 2 800 ? 152.358 166.000 120.910 1.00 110.70 ? 800 LEU A CG  1 
ATOM 6366 C CD1 . LEU B 2 800 ? 150.977 165.520 120.505 1.00 114.52 ? 800 LEU A CD1 1 
ATOM 6367 C CD2 . LEU B 2 800 ? 153.393 165.453 119.945 1.00 110.98 ? 800 LEU A CD2 1 
ATOM 6368 N N   . TYR B 2 801 ? 153.248 169.754 123.043 1.00 118.70 ? 801 TYR A N   1 
ATOM 6369 C CA  . TYR B 2 801 ? 153.065 171.099 123.581 1.00 117.02 ? 801 TYR A CA  1 
ATOM 6370 C C   . TYR B 2 801 ? 154.366 171.893 123.583 1.00 121.23 ? 801 TYR A C   1 
ATOM 6371 O O   . TYR B 2 801 ? 154.339 173.123 123.457 1.00 125.35 ? 801 TYR A O   1 
ATOM 6372 C CB  . TYR B 2 801 ? 152.487 171.045 124.993 1.00 115.60 ? 801 TYR A CB  1 
ATOM 6373 C CG  . TYR B 2 801 ? 152.292 172.417 125.597 1.00 118.87 ? 801 TYR A CG  1 
ATOM 6374 C CD1 . TYR B 2 801 ? 151.249 173.234 125.185 1.00 119.30 ? 801 TYR A CD1 1 
ATOM 6375 C CD2 . TYR B 2 801 ? 153.160 172.901 126.564 1.00 121.90 ? 801 TYR A CD2 1 
ATOM 6376 C CE1 . TYR B 2 801 ? 151.069 174.490 125.728 1.00 118.15 ? 801 TYR A CE1 1 
ATOM 6377 C CE2 . TYR B 2 801 ? 152.989 174.157 127.112 1.00 122.95 ? 801 TYR A CE2 1 
ATOM 6378 C CZ  . TYR B 2 801 ? 151.942 174.946 126.690 1.00 119.63 ? 801 TYR A CZ  1 
ATOM 6379 O OH  . TYR B 2 801 ? 151.769 176.197 127.235 1.00 119.81 ? 801 TYR A OH  1 
ATOM 6380 N N   . VAL B 2 802 ? 155.506 171.217 123.717 1.00 120.25 ? 802 VAL A N   1 
ATOM 6381 C CA  . VAL B 2 802 ? 156.783 171.902 123.864 1.00 117.63 ? 802 VAL A CA  1 
ATOM 6382 C C   . VAL B 2 802 ? 157.447 172.219 122.531 1.00 117.44 ? 802 VAL A C   1 
ATOM 6383 O O   . VAL B 2 802 ? 158.323 173.094 122.481 1.00 119.86 ? 802 VAL A O   1 
ATOM 6384 C CB  . VAL B 2 802 ? 157.732 171.057 124.737 1.00 119.60 ? 802 VAL A CB  1 
ATOM 6385 C CG1 . VAL B 2 802 ? 158.470 170.028 123.897 1.00 122.99 ? 802 VAL A CG1 1 
ATOM 6386 C CG2 . VAL B 2 802 ? 158.715 171.935 125.471 1.00 116.92 ? 802 VAL A CG2 1 
ATOM 6387 N N   . PHE B 2 803 ? 157.059 171.544 121.450 1.00 119.55 ? 803 PHE A N   1 
ATOM 6388 C CA  . PHE B 2 803 ? 157.709 171.757 120.165 1.00 120.74 ? 803 PHE A CA  1 
ATOM 6389 C C   . PHE B 2 803 ? 156.812 172.376 119.106 1.00 123.25 ? 803 PHE A C   1 
ATOM 6390 O O   . PHE B 2 803 ? 157.315 173.096 118.242 1.00 124.55 ? 803 PHE A O   1 
ATOM 6391 C CB  . PHE B 2 803 ? 158.267 170.433 119.629 1.00 121.66 ? 803 PHE A CB  1 
ATOM 6392 C CG  . PHE B 2 803 ? 159.550 170.012 120.284 1.00 125.56 ? 803 PHE A CG  1 
ATOM 6393 C CD1 . PHE B 2 803 ? 160.403 170.954 120.832 1.00 124.19 ? 803 PHE A CD1 1 
ATOM 6394 C CD2 . PHE B 2 803 ? 159.903 168.675 120.355 1.00 125.67 ? 803 PHE A CD2 1 
ATOM 6395 C CE1 . PHE B 2 803 ? 161.584 170.572 121.437 1.00 123.02 ? 803 PHE A CE1 1 
ATOM 6396 C CE2 . PHE B 2 803 ? 161.083 168.287 120.959 1.00 124.45 ? 803 PHE A CE2 1 
ATOM 6397 C CZ  . PHE B 2 803 ? 161.925 169.238 121.500 1.00 123.70 ? 803 PHE A CZ  1 
ATOM 6398 N N   . PHE B 2 804 ? 155.504 172.121 119.145 1.00 131.12 ? 804 PHE A N   1 
ATOM 6399 C CA  . PHE B 2 804 ? 154.600 172.544 118.082 1.00 133.86 ? 804 PHE A CA  1 
ATOM 6400 C C   . PHE B 2 804 ? 153.607 173.610 118.538 1.00 134.23 ? 804 PHE A C   1 
ATOM 6401 O O   . PHE B 2 804 ? 152.568 173.795 117.896 1.00 133.62 ? 804 PHE A O   1 
ATOM 6402 C CB  . PHE B 2 804 ? 153.850 171.337 117.514 1.00 133.45 ? 804 PHE A CB  1 
ATOM 6403 C CG  . PHE B 2 804 ? 154.747 170.268 116.946 1.00 134.10 ? 804 PHE A CG  1 
ATOM 6404 C CD1 . PHE B 2 804 ? 156.036 170.564 116.534 1.00 133.46 ? 804 PHE A CD1 1 
ATOM 6405 C CD2 . PHE B 2 804 ? 154.296 168.965 116.826 1.00 133.15 ? 804 PHE A CD2 1 
ATOM 6406 C CE1 . PHE B 2 804 ? 156.856 169.581 116.017 1.00 133.93 ? 804 PHE A CE1 1 
ATOM 6407 C CE2 . PHE B 2 804 ? 155.112 167.978 116.308 1.00 132.31 ? 804 PHE A CE2 1 
ATOM 6408 C CZ  . PHE B 2 804 ? 156.393 168.287 115.903 1.00 134.45 ? 804 PHE A CZ  1 
ATOM 6409 N N   . ASN B 2 805 ? 153.898 174.313 119.626 1.00 138.13 ? 805 ASN A N   1 
ATOM 6410 C CA  . ASN B 2 805 ? 152.997 175.335 120.160 1.00 136.66 ? 805 ASN A CA  1 
ATOM 6411 C C   . ASN B 2 805 ? 153.769 176.610 120.464 1.00 137.06 ? 805 ASN A C   1 
ATOM 6412 O O   . ASN B 2 805 ? 154.602 176.618 121.395 1.00 137.22 ? 805 ASN A O   1 
ATOM 6413 C CB  . ASN B 2 805 ? 152.283 174.829 121.410 1.00 135.67 ? 805 ASN A CB  1 
ATOM 6414 C CG  . ASN B 2 805 ? 150.930 174.222 121.102 1.00 135.27 ? 805 ASN A CG  1 
ATOM 6415 O OD1 . ASN B 2 805 ? 150.753 173.556 120.083 1.00 137.94 ? 805 ASN A OD1 1 
ATOM 6416 N ND2 . ASN B 2 805 ? 149.966 174.449 121.985 1.00 135.22 ? 805 ASN A ND2 1 
ATOM 6417 N N   . PRO B 2 806 ? 153.539 177.696 119.723 1.00 145.47 ? 806 PRO A N   1 
ATOM 6418 C CA  . PRO B 2 806 ? 154.211 178.966 120.049 1.00 146.20 ? 806 PRO A CA  1 
ATOM 6419 C C   . PRO B 2 806 ? 153.721 179.440 121.404 1.00 148.18 ? 806 PRO A C   1 
ATOM 6420 O O   . PRO B 2 806 ? 154.387 180.276 122.032 1.00 150.49 ? 806 PRO A O   1 
ATOM 6421 C CB  . PRO B 2 806 ? 153.780 179.893 118.905 1.00 147.03 ? 806 PRO A CB  1 
ATOM 6422 C CG  . PRO B 2 806 ? 152.490 179.317 118.423 1.00 145.25 ? 806 PRO A CG  1 
ATOM 6423 C CD  . PRO B 2 806 ? 152.614 177.831 118.585 1.00 144.15 ? 806 PRO A CD  1 
ATOM 6424 N N   . LYS B 2 807 ? 152.573 178.942 121.871 1.00 151.74 ? 807 LYS A N   1 
ATOM 6425 C CA  . LYS B 2 807 ? 152.107 179.304 123.207 1.00 152.27 ? 807 LYS A CA  1 
ATOM 6426 C C   . LYS B 2 807 ? 153.182 179.033 124.266 1.00 151.79 ? 807 LYS A C   1 
ATOM 6427 O O   . LYS B 2 807 ? 153.539 179.907 125.068 1.00 151.17 ? 807 LYS A O   1 
ATOM 6428 C CB  . LYS B 2 807 ? 150.781 178.604 123.508 1.00 151.29 ? 807 LYS A CB  1 
ATOM 6429 C CG  . LYS B 2 807 ? 149.677 178.906 122.506 1.00 150.01 ? 807 LYS A CG  1 
ATOM 6430 C CD  . LYS B 2 807 ? 149.380 180.394 122.437 1.00 152.23 ? 807 LYS A CD  1 
ATOM 6431 C CE  . LYS B 2 807 ? 148.703 180.881 123.707 1.00 154.14 ? 807 LYS A CE  1 
ATOM 6432 N NZ  . LYS B 2 807 ? 148.255 182.297 123.587 1.00 154.61 ? 807 LYS A NZ  1 
ATOM 6433 N N   . PHE B 2 808 ? 153.743 177.822 124.235 1.00 142.42 ? 808 PHE A N   1 
ATOM 6434 C CA  . PHE B 2 808 ? 154.901 177.549 125.074 1.00 143.83 ? 808 PHE A CA  1 
ATOM 6435 C C   . PHE B 2 808 ? 156.153 178.393 124.904 1.00 145.32 ? 808 PHE A C   1 
ATOM 6436 O O   . PHE B 2 808 ? 156.863 178.637 125.880 1.00 147.80 ? 808 PHE A O   1 
ATOM 6437 C CB  . PHE B 2 808 ? 155.265 176.078 124.883 1.00 142.63 ? 808 PHE A CB  1 
ATOM 6438 C CG  . PHE B 2 808 ? 156.501 175.682 125.634 1.00 142.46 ? 808 PHE A CG  1 
ATOM 6439 C CD1 . PHE B 2 808 ? 156.435 175.371 126.979 1.00 140.01 ? 808 PHE A CD1 1 
ATOM 6440 C CD2 . PHE B 2 808 ? 157.736 175.664 125.006 1.00 142.30 ? 808 PHE A CD2 1 
ATOM 6441 C CE1 . PHE B 2 808 ? 157.570 175.030 127.678 1.00 139.07 ? 808 PHE A CE1 1 
ATOM 6442 C CE2 . PHE B 2 808 ? 158.875 175.329 125.702 1.00 141.77 ? 808 PHE A CE2 1 
ATOM 6443 C CZ  . PHE B 2 808 ? 158.792 175.010 127.039 1.00 141.86 ? 808 PHE A CZ  1 
ATOM 6444 N N   . LYS B 2 809 ? 156.464 178.815 123.678 1.00 155.54 ? 809 LYS A N   1 
ATOM 6445 C CA  . LYS B 2 809 ? 157.633 179.668 123.483 1.00 157.06 ? 809 LYS A CA  1 
ATOM 6446 C C   . LYS B 2 809 ? 157.457 181.020 124.170 1.00 158.75 ? 809 LYS A C   1 
ATOM 6447 O O   . LYS B 2 809 ? 158.392 181.543 124.791 1.00 157.82 ? 809 LYS A O   1 
ATOM 6448 C CB  . LYS B 2 809 ? 157.884 179.884 121.991 1.00 155.07 ? 809 LYS A CB  1 
ATOM 6449 C CG  . LYS B 2 809 ? 158.316 178.634 121.248 1.00 154.92 ? 809 LYS A CG  1 
ATOM 6450 C CD  . LYS B 2 809 ? 158.522 178.921 119.769 1.00 156.57 ? 809 LYS A CD  1 
ATOM 6451 C CE  . LYS B 2 809 ? 158.978 177.679 119.025 1.00 157.08 ? 809 LYS A CE  1 
ATOM 6452 N NZ  . LYS B 2 809 ? 159.161 177.941 117.571 1.00 158.11 ? 809 LYS A NZ  1 
ATOM 6453 N N   . GLU B 2 810 ? 156.250 181.586 124.089 1.00 166.13 ? 810 GLU A N   1 
ATOM 6454 C CA  . GLU B 2 810 ? 155.978 182.840 124.786 1.00 164.43 ? 810 GLU A CA  1 
ATOM 6455 C C   . GLU B 2 810 ? 156.096 182.613 126.288 1.00 163.52 ? 810 GLU A C   1 
ATOM 6456 O O   . GLU B 2 810 ? 156.671 183.441 127.007 1.00 162.74 ? 810 GLU A O   1 
ATOM 6457 C CB  . GLU B 2 810 ? 154.602 183.409 124.440 1.00 163.11 ? 810 GLU A CB  1 
ATOM 6458 C CG  . GLU B 2 810 ? 154.238 183.329 122.968 1.00 164.70 ? 810 GLU A CG  1 
ATOM 6459 C CD  . GLU B 2 810 ? 155.350 183.820 122.063 1.00 166.49 ? 810 GLU A CD  1 
ATOM 6460 O OE1 . GLU B 2 810 ? 155.642 185.034 122.084 1.00 166.22 ? 810 GLU A OE1 1 
ATOM 6461 O OE2 . GLU B 2 810 ? 155.933 182.992 121.333 1.00 166.59 ? 810 GLU A OE2 1 
ATOM 6462 N N   . ASP B 2 811 ? 155.558 181.495 126.780 1.00 159.98 ? 811 ASP A N   1 
ATOM 6463 C CA  . ASP B 2 811 ? 155.640 181.203 128.208 1.00 160.42 ? 811 ASP A CA  1 
ATOM 6464 C C   . ASP B 2 811 ? 157.085 181.006 128.650 1.00 159.95 ? 811 ASP A C   1 
ATOM 6465 O O   . ASP B 2 811 ? 157.475 181.444 129.736 1.00 158.77 ? 811 ASP A O   1 
ATOM 6466 C CB  . ASP B 2 811 ? 154.802 179.969 128.538 1.00 161.57 ? 811 ASP A CB  1 
ATOM 6467 C CG  . ASP B 2 811 ? 153.328 180.289 128.675 1.00 161.25 ? 811 ASP A CG  1 
ATOM 6468 O OD1 . ASP B 2 811 ? 152.976 181.115 129.543 1.00 159.97 ? 811 ASP A OD1 1 
ATOM 6469 O OD2 . ASP B 2 811 ? 152.521 179.717 127.913 1.00 162.27 ? 811 ASP A OD2 1 
ATOM 6470 N N   . TRP B 2 812 ? 157.892 180.343 127.821 1.00 164.75 ? 812 TRP A N   1 
ATOM 6471 C CA  . TRP B 2 812 ? 159.301 180.141 128.137 1.00 165.13 ? 812 TRP A CA  1 
ATOM 6472 C C   . TRP B 2 812 ? 160.059 181.460 128.134 1.00 165.85 ? 812 TRP A C   1 
ATOM 6473 O O   . TRP B 2 812 ? 160.933 181.682 128.979 1.00 166.78 ? 812 TRP A O   1 
ATOM 6474 C CB  . TRP B 2 812 ? 159.921 179.160 127.144 1.00 164.50 ? 812 TRP A CB  1 
ATOM 6475 C CG  . TRP B 2 812 ? 161.413 179.086 127.210 1.00 165.51 ? 812 TRP A CG  1 
ATOM 6476 C CD1 . TRP B 2 812 ? 162.302 179.713 126.386 1.00 164.89 ? 812 TRP A CD1 1 
ATOM 6477 C CD2 . TRP B 2 812 ? 162.195 178.336 128.146 1.00 165.91 ? 812 TRP A CD2 1 
ATOM 6478 N NE1 . TRP B 2 812 ? 163.588 179.403 126.754 1.00 166.00 ? 812 TRP A NE1 1 
ATOM 6479 C CE2 . TRP B 2 812 ? 163.549 178.558 127.832 1.00 166.79 ? 812 TRP A CE2 1 
ATOM 6480 C CE3 . TRP B 2 812 ? 161.880 177.499 129.220 1.00 164.69 ? 812 TRP A CE3 1 
ATOM 6481 C CZ2 . TRP B 2 812 ? 164.588 177.974 128.553 1.00 165.58 ? 812 TRP A CZ2 1 
ATOM 6482 C CZ3 . TRP B 2 812 ? 162.912 176.921 129.935 1.00 164.50 ? 812 TRP A CZ3 1 
ATOM 6483 C CH2 . TRP B 2 812 ? 164.250 177.161 129.598 1.00 163.74 ? 812 TRP A CH2 1 
ATOM 6484 N N   . LYS B 2 813 ? 159.745 182.345 127.185 1.00 166.46 ? 813 LYS A N   1 
ATOM 6485 C CA  . LYS B 2 813 ? 160.359 183.669 127.192 1.00 166.90 ? 813 LYS A CA  1 
ATOM 6486 C C   . LYS B 2 813 ? 160.000 184.429 128.462 1.00 167.09 ? 813 LYS A C   1 
ATOM 6487 O O   . LYS B 2 813 ? 160.862 185.068 129.079 1.00 165.24 ? 813 LYS A O   1 
ATOM 6488 C CB  . LYS B 2 813 ? 159.929 184.455 125.954 1.00 165.89 ? 813 LYS A CB  1 
ATOM 6489 C CG  . LYS B 2 813 ? 160.684 185.760 125.756 1.00 166.08 ? 813 LYS A CG  1 
ATOM 6490 C CD  . LYS B 2 813 ? 162.185 185.557 125.879 1.00 165.30 ? 813 LYS A CD  1 
ATOM 6491 C CE  . LYS B 2 813 ? 162.745 184.825 124.669 1.00 165.16 ? 813 LYS A CE  1 
ATOM 6492 N NZ  . LYS B 2 813 ? 164.060 184.193 124.965 1.00 164.41 ? 813 LYS A NZ  1 
ATOM 6493 N N   . LEU B 2 814 ? 158.732 184.361 128.873 1.00 174.56 ? 814 LEU A N   1 
ATOM 6494 C CA  . LEU B 2 814 ? 158.316 185.020 130.108 1.00 175.61 ? 814 LEU A CA  1 
ATOM 6495 C C   . LEU B 2 814 ? 159.024 184.423 131.319 1.00 175.94 ? 814 LEU A C   1 
ATOM 6496 O O   . LEU B 2 814 ? 159.430 185.151 132.233 1.00 176.36 ? 814 LEU A O   1 
ATOM 6497 C CB  . LEU B 2 814 ? 156.799 184.918 130.268 1.00 174.03 ? 814 LEU A CB  1 
ATOM 6498 C CG  . LEU B 2 814 ? 156.192 185.617 131.485 1.00 173.50 ? 814 LEU A CG  1 
ATOM 6499 C CD1 . LEU B 2 814 ? 156.669 187.058 131.571 1.00 174.50 ? 814 LEU A CD1 1 
ATOM 6500 C CD2 . LEU B 2 814 ? 154.674 185.551 131.440 1.00 172.33 ? 814 LEU A CD2 1 
ATOM 6501 N N   . LEU B 2 815 ? 159.169 183.097 131.348 1.00 179.14 ? 815 LEU A N   1 
ATOM 6502 C CA  . LEU B 2 815 ? 159.857 182.445 132.457 1.00 179.16 ? 815 LEU A CA  1 
ATOM 6503 C C   . LEU B 2 815 ? 161.318 182.866 132.519 1.00 179.04 ? 815 LEU A C   1 
ATOM 6504 O O   . LEU B 2 815 ? 161.853 183.116 133.605 1.00 177.75 ? 815 LEU A O   1 
ATOM 6505 C CB  . LEU B 2 815 ? 159.741 180.926 132.325 1.00 178.67 ? 815 LEU A CB  1 
ATOM 6506 C CG  . LEU B 2 815 ? 160.740 180.080 133.121 1.00 178.26 ? 815 LEU A CG  1 
ATOM 6507 C CD1 . LEU B 2 815 ? 160.561 180.288 134.620 1.00 178.08 ? 815 LEU A CD1 1 
ATOM 6508 C CD2 . LEU B 2 815 ? 160.617 178.609 132.763 1.00 177.73 ? 815 LEU A CD2 1 
ATOM 6509 N N   . LYS B 2 816 ? 161.983 182.941 131.365 1.00 188.62 ? 816 LYS A N   1 
ATOM 6510 C CA  . LYS B 2 816 ? 163.370 183.393 131.342 1.00 189.11 ? 816 LYS A CA  1 
ATOM 6511 C C   . LYS B 2 816 ? 163.499 184.838 131.809 1.00 190.55 ? 816 LYS A C   1 
ATOM 6512 O O   . LYS B 2 816 ? 164.442 185.183 132.532 1.00 191.03 ? 816 LYS A O   1 
ATOM 6513 C CB  . LYS B 2 816 ? 163.956 183.226 129.940 1.00 188.61 ? 816 LYS A CB  1 
ATOM 6514 C CG  . LYS B 2 816 ? 165.473 183.323 129.882 1.00 188.00 ? 816 LYS A CG  1 
ATOM 6515 C CD  . LYS B 2 816 ? 166.125 182.620 131.065 1.00 188.10 ? 816 LYS A CD  1 
ATOM 6516 C CE  . LYS B 2 816 ? 166.236 181.122 130.829 1.00 186.79 ? 816 LYS A CE  1 
ATOM 6517 N NZ  . LYS B 2 816 ? 166.985 180.442 131.923 1.00 184.99 ? 816 LYS A NZ  1 
ATOM 6518 N N   . ARG B 2 817 ? 162.560 185.695 131.403 1.00 202.15 ? 817 ARG A N   1 
ATOM 6519 C CA  . ARG B 2 817 ? 162.572 187.079 131.868 1.00 202.94 ? 817 ARG A CA  1 
ATOM 6520 C C   . ARG B 2 817 ? 162.389 187.158 133.379 1.00 203.54 ? 817 ARG A C   1 
ATOM 6521 O O   . ARG B 2 817 ? 163.053 187.955 134.053 1.00 204.62 ? 817 ARG A O   1 
ATOM 6522 C CB  . ARG B 2 817 ? 161.477 187.877 131.162 1.00 200.65 ? 817 ARG A CB  1 
ATOM 6523 C CG  . ARG B 2 817 ? 161.436 189.347 131.547 1.00 199.84 ? 817 ARG A CG  1 
ATOM 6524 C CD  . ARG B 2 817 ? 160.499 190.128 130.640 1.00 201.67 ? 817 ARG A CD  1 
ATOM 6525 N NE  . ARG B 2 817 ? 160.984 190.176 129.266 1.00 202.57 ? 817 ARG A NE  1 
ATOM 6526 C CZ  . ARG B 2 817 ? 160.453 189.494 128.259 1.00 202.78 ? 817 ARG A CZ  1 
ATOM 6527 N NH1 . ARG B 2 817 ? 159.414 188.694 128.438 1.00 202.74 ? 817 ARG A NH1 1 
ATOM 6528 N NH2 . ARG B 2 817 ? 160.978 189.616 127.044 1.00 201.51 ? 817 ARG A NH2 1 
ATOM 6529 N N   . ARG B 2 818 ? 161.490 186.339 133.928 1.00 197.55 ? 818 ARG A N   1 
ATOM 6530 C CA  . ARG B 2 818 ? 161.289 186.318 135.374 1.00 196.67 ? 818 ARG A CA  1 
ATOM 6531 C C   . ARG B 2 818 ? 162.542 185.814 136.080 1.00 197.43 ? 818 ARG A C   1 
ATOM 6532 O O   . ARG B 2 818 ? 162.919 186.329 137.139 1.00 196.88 ? 818 ARG A O   1 
ATOM 6533 C CB  . ARG B 2 818 ? 160.082 185.454 135.739 1.00 195.06 ? 818 ARG A CB  1 
ATOM 6534 C CG  . ARG B 2 818 ? 159.577 185.655 137.160 1.00 194.97 ? 818 ARG A CG  1 
ATOM 6535 C CD  . ARG B 2 818 ? 160.010 184.516 138.070 1.00 196.16 ? 818 ARG A CD  1 
ATOM 6536 N NE  . ARG B 2 818 ? 159.312 184.543 139.350 1.00 195.56 ? 818 ARG A NE  1 
ATOM 6537 C CZ  . ARG B 2 818 ? 159.378 183.580 140.260 1.00 195.08 ? 818 ARG A CZ  1 
ATOM 6538 N NH1 . ARG B 2 818 ? 160.105 182.493 140.065 1.00 194.04 ? 818 ARG A NH1 1 
ATOM 6539 N NH2 . ARG B 2 818 ? 158.696 183.712 141.394 1.00 194.32 ? 818 ARG A NH2 1 
ATOM 6540 N N   . VAL B 2 819 ? 163.194 184.799 135.510 1.00 201.53 ? 819 VAL A N   1 
ATOM 6541 C CA  . VAL B 2 819 ? 164.398 184.239 136.116 1.00 201.38 ? 819 VAL A CA  1 
ATOM 6542 C C   . VAL B 2 819 ? 165.522 185.267 136.126 1.00 202.80 ? 819 VAL A C   1 
ATOM 6543 O O   . VAL B 2 819 ? 166.243 185.409 137.122 1.00 201.82 ? 819 VAL A O   1 
ATOM 6544 C CB  . VAL B 2 819 ? 164.809 182.950 135.381 1.00 199.45 ? 819 VAL A CB  1 
ATOM 6545 C CG1 . VAL B 2 819 ? 166.287 182.652 135.594 1.00 197.38 ? 819 VAL A CG1 1 
ATOM 6546 C CG2 . VAL B 2 819 ? 163.953 181.781 135.844 1.00 198.22 ? 819 VAL A CG2 1 
ATOM 6547 N N   . THR B 2 820 ? 165.688 186.003 135.023 1.00 210.02 ? 820 THR A N   1 
ATOM 6548 C CA  . THR B 2 820 ? 166.764 186.987 134.943 1.00 208.59 ? 820 THR A CA  1 
ATOM 6549 C C   . THR B 2 820 ? 166.605 188.087 135.986 1.00 209.69 ? 820 THR A C   1 
ATOM 6550 O O   . THR B 2 820 ? 167.602 188.674 136.422 1.00 208.83 ? 820 THR A O   1 
ATOM 6551 C CB  . THR B 2 820 ? 166.820 187.595 133.542 1.00 206.97 ? 820 THR A CB  1 
ATOM 6552 O OG1 . THR B 2 820 ? 165.490 187.760 133.037 1.00 208.13 ? 820 THR A OG1 1 
ATOM 6553 C CG2 . THR B 2 820 ? 167.605 186.692 132.602 1.00 205.45 ? 820 THR A CG2 1 
ATOM 6554 N N   . LYS B 2 821 ? 165.375 188.381 136.393 1.00 204.82 ? 821 LYS A N   1 
ATOM 6555 C CA  . LYS B 2 821 ? 165.129 189.396 137.412 1.00 202.45 ? 821 LYS A CA  1 
ATOM 6556 C C   . LYS B 2 821 ? 165.627 188.933 138.777 1.00 200.76 ? 821 LYS A C   1 
ATOM 6557 O O   . LYS B 2 821 ? 165.734 187.735 139.036 1.00 199.14 ? 821 LYS A O   1 
ATOM 6558 C CB  . LYS B 2 821 ? 163.640 189.737 137.484 1.00 201.57 ? 821 LYS A CB  1 
ATOM 6559 C CG  . LYS B 2 821 ? 163.140 190.594 136.332 1.00 200.40 ? 821 LYS A CG  1 
ATOM 6560 C CD  . LYS B 2 821 ? 161.691 190.281 135.978 1.00 200.84 ? 821 LYS A CD  1 
ATOM 6561 C CE  . LYS B 2 821 ? 160.882 189.881 137.204 1.00 201.03 ? 821 LYS A CE  1 
ATOM 6562 N NZ  . LYS B 2 821 ? 159.676 189.087 136.839 1.00 200.80 ? 821 LYS A NZ  1 
ATOM 6563 N N   . ILE C 3 39  ? 129.771 84.491  114.447 1.00 200.33 ? 39  ILE B N   1 
ATOM 6564 C CA  . ILE C 3 39  ? 129.925 85.938  114.522 1.00 201.01 ? 39  ILE B CA  1 
ATOM 6565 C C   . ILE C 3 39  ? 129.106 86.493  115.682 1.00 202.35 ? 39  ILE B C   1 
ATOM 6566 O O   . ILE C 3 39  ? 129.454 86.301  116.847 1.00 202.40 ? 39  ILE B O   1 
ATOM 6567 C CB  . ILE C 3 39  ? 129.522 86.610  113.198 1.00 200.95 ? 39  ILE B CB  1 
ATOM 6568 N N   . CYS C 3 40  ? 128.017 87.182  115.356 1.00 208.14 ? 40  CYS B N   1 
ATOM 6569 C CA  . CYS C 3 40  ? 127.125 87.758  116.353 1.00 207.75 ? 40  CYS B CA  1 
ATOM 6570 C C   . CYS C 3 40  ? 125.877 86.895  116.477 1.00 206.81 ? 40  CYS B C   1 
ATOM 6571 O O   . CYS C 3 40  ? 125.214 86.605  115.475 1.00 206.41 ? 40  CYS B O   1 
ATOM 6572 C CB  . CYS C 3 40  ? 126.748 89.194  115.984 1.00 207.61 ? 40  CYS B CB  1 
ATOM 6573 S SG  . CYS C 3 40  ? 128.165 90.297  115.775 1.00 209.72 ? 40  CYS B SG  1 
ATOM 6574 N N   . LYS C 3 41  ? 125.564 86.486  117.705 1.00 188.04 ? 41  LYS B N   1 
ATOM 6575 C CA  . LYS C 3 41  ? 124.452 85.577  117.967 1.00 187.32 ? 41  LYS B CA  1 
ATOM 6576 C C   . LYS C 3 41  ? 123.743 86.051  119.227 1.00 187.00 ? 41  LYS B C   1 
ATOM 6577 O O   . LYS C 3 41  ? 124.305 85.973  120.323 1.00 186.77 ? 41  LYS B O   1 
ATOM 6578 C CB  . LYS C 3 41  ? 124.951 84.140  118.124 1.00 186.66 ? 41  LYS B CB  1 
ATOM 6579 C CG  . LYS C 3 41  ? 123.898 83.117  118.532 1.00 186.11 ? 41  LYS B CG  1 
ATOM 6580 C CD  . LYS C 3 41  ? 122.801 82.986  117.486 1.00 185.79 ? 41  LYS B CD  1 
ATOM 6581 C CE  . LYS C 3 41  ? 121.423 82.867  118.121 1.00 185.42 ? 41  LYS B CE  1 
ATOM 6582 N NZ  . LYS C 3 41  ? 120.934 84.143  118.699 1.00 183.98 ? 41  LYS B NZ  1 
ATOM 6583 N N   . GLY C 3 42  ? 122.514 86.537  119.073 1.00 185.96 ? 42  GLY B N   1 
ATOM 6584 C CA  . GLY C 3 42  ? 121.713 86.951  120.208 1.00 186.04 ? 42  GLY B CA  1 
ATOM 6585 C C   . GLY C 3 42  ? 122.257 88.137  120.977 1.00 186.04 ? 42  GLY B C   1 
ATOM 6586 O O   . GLY C 3 42  ? 122.329 88.102  122.208 1.00 185.55 ? 42  GLY B O   1 
ATOM 6587 N N   . CYS C 3 43  ? 122.657 89.188  120.266 1.00 197.13 ? 43  CYS B N   1 
ATOM 6588 C CA  . CYS C 3 43  ? 123.102 90.426  120.890 1.00 197.39 ? 43  CYS B CA  1 
ATOM 6589 C C   . CYS C 3 43  ? 122.394 91.604  120.241 1.00 198.14 ? 43  CYS B C   1 
ATOM 6590 O O   . CYS C 3 43  ? 122.159 91.607  119.029 1.00 197.17 ? 43  CYS B O   1 
ATOM 6591 C CB  . CYS C 3 43  ? 124.622 90.594  120.781 1.00 199.21 ? 43  CYS B CB  1 
ATOM 6592 S SG  . CYS C 3 43  ? 125.329 90.028  119.220 1.00 205.21 ? 43  CYS B SG  1 
ATOM 6593 N N   . LEU C 3 44  ? 122.047 92.602  121.059 1.00 198.77 ? 44  LEU B N   1 
ATOM 6594 C CA  . LEU C 3 44  ? 121.360 93.781  120.541 1.00 199.14 ? 44  LEU B CA  1 
ATOM 6595 C C   . LEU C 3 44  ? 122.240 94.550  119.564 1.00 200.55 ? 44  LEU B C   1 
ATOM 6596 O O   . LEU C 3 44  ? 121.769 94.996  118.511 1.00 199.56 ? 44  LEU B O   1 
ATOM 6597 C CB  . LEU C 3 44  ? 120.927 94.686  121.694 1.00 198.62 ? 44  LEU B CB  1 
ATOM 6598 C CG  . LEU C 3 44  ? 119.742 94.209  122.534 1.00 197.55 ? 44  LEU B CG  1 
ATOM 6599 C CD1 . LEU C 3 44  ? 119.275 95.310  123.473 1.00 198.08 ? 44  LEU B CD1 1 
ATOM 6600 C CD2 . LEU C 3 44  ? 118.604 93.741  121.640 1.00 197.47 ? 44  LEU B CD2 1 
ATOM 6601 N N   . SER C 3 45  ? 123.517 94.716  119.895 1.00 209.62 ? 45  SER B N   1 
ATOM 6602 C CA  . SER C 3 45  ? 124.468 95.416  119.046 1.00 207.34 ? 45  SER B CA  1 
ATOM 6603 C C   . SER C 3 45  ? 125.569 94.457  118.620 1.00 207.43 ? 45  SER B C   1 
ATOM 6604 O O   . SER C 3 45  ? 126.104 93.704  119.441 1.00 208.80 ? 45  SER B O   1 
ATOM 6605 C CB  . SER C 3 45  ? 125.070 96.626  119.768 1.00 206.23 ? 45  SER B CB  1 
ATOM 6606 O OG  . SER C 3 45  ? 125.676 96.242  120.989 1.00 206.82 ? 45  SER B OG  1 
ATOM 6607 N N   . CYS C 3 46  ? 125.903 94.486  117.331 1.00 219.27 ? 46  CYS B N   1 
ATOM 6608 C CA  . CYS C 3 46  ? 126.903 93.593  116.749 1.00 220.98 ? 46  CYS B CA  1 
ATOM 6609 C C   . CYS C 3 46  ? 128.003 94.446  116.126 1.00 222.58 ? 46  CYS B C   1 
ATOM 6610 O O   . CYS C 3 46  ? 127.832 94.990  115.031 1.00 222.23 ? 46  CYS B O   1 
ATOM 6611 C CB  . CYS C 3 46  ? 126.271 92.661  115.719 1.00 220.12 ? 46  CYS B CB  1 
ATOM 6612 S SG  . CYS C 3 46  ? 127.451 91.821  114.639 1.00 224.22 ? 46  CYS B SG  1 
ATOM 6613 N N   . SER C 3 47  ? 129.127 94.564  116.825 1.00 223.67 ? 47  SER B N   1 
ATOM 6614 C CA  . SER C 3 47  ? 130.294 95.284  116.341 1.00 221.79 ? 47  SER B CA  1 
ATOM 6615 C C   . SER C 3 47  ? 131.458 94.320  116.161 1.00 222.14 ? 47  SER B C   1 
ATOM 6616 O O   . SER C 3 47  ? 131.592 93.331  116.885 1.00 222.59 ? 47  SER B O   1 
ATOM 6617 C CB  . SER C 3 47  ? 130.686 96.410  117.303 1.00 220.35 ? 47  SER B CB  1 
ATOM 6618 O OG  . SER C 3 47  ? 132.062 96.726  117.182 1.00 219.76 ? 47  SER B OG  1 
ATOM 6619 N N   . LYS C 3 48  ? 132.306 94.617  115.174 1.00 219.28 ? 48  LYS B N   1 
ATOM 6620 C CA  . LYS C 3 48  ? 133.424 93.728  114.880 1.00 219.29 ? 48  LYS B CA  1 
ATOM 6621 C C   . LYS C 3 48  ? 134.436 93.741  116.023 1.00 220.40 ? 48  LYS B C   1 
ATOM 6622 O O   . LYS C 3 48  ? 134.903 92.682  116.460 1.00 220.44 ? 48  LYS B O   1 
ATOM 6623 C CB  . LYS C 3 48  ? 134.071 94.144  113.549 1.00 218.21 ? 48  LYS B CB  1 
ATOM 6624 C CG  . LYS C 3 48  ? 135.481 93.602  113.166 1.00 217.92 ? 48  LYS B CG  1 
ATOM 6625 C CD  . LYS C 3 48  ? 135.855 92.180  113.629 1.00 217.63 ? 48  LYS B CD  1 
ATOM 6626 C CE  . LYS C 3 48  ? 134.809 91.129  113.261 1.00 216.83 ? 48  LYS B CE  1 
ATOM 6627 N NZ  . LYS C 3 48  ? 135.267 89.745  113.567 1.00 215.91 ? 48  LYS B NZ  1 
ATOM 6628 N N   . ASP C 3 49  ? 134.755 94.927  116.544 1.00 229.49 ? 49  ASP B N   1 
ATOM 6629 C CA  . ASP C 3 49  ? 135.806 95.045  117.551 1.00 229.60 ? 49  ASP B CA  1 
ATOM 6630 C C   . ASP C 3 49  ? 135.413 94.360  118.856 1.00 229.38 ? 49  ASP B C   1 
ATOM 6631 O O   . ASP C 3 49  ? 136.196 93.590  119.424 1.00 229.05 ? 49  ASP B O   1 
ATOM 6632 C CB  . ASP C 3 49  ? 136.130 96.519  117.793 1.00 229.81 ? 49  ASP B CB  1 
ATOM 6633 C CG  . ASP C 3 49  ? 137.298 96.711  118.737 1.00 229.83 ? 49  ASP B CG  1 
ATOM 6634 O OD1 . ASP C 3 49  ? 138.137 95.792  118.842 1.00 229.19 ? 49  ASP B OD1 1 
ATOM 6635 O OD2 . ASP C 3 49  ? 137.376 97.782  119.374 1.00 229.86 ? 49  ASP B OD2 1 
ATOM 6636 N N   . ASN C 3 50  ? 134.206 94.629  119.351 1.00 220.67 ? 50  ASN B N   1 
ATOM 6637 C CA  . ASN C 3 50  ? 133.758 94.106  120.634 1.00 220.16 ? 50  ASN B CA  1 
ATOM 6638 C C   . ASN C 3 50  ? 132.830 92.905  120.499 1.00 220.26 ? 50  ASN B C   1 
ATOM 6639 O O   . ASN C 3 50  ? 132.256 92.467  121.502 1.00 220.45 ? 50  ASN B O   1 
ATOM 6640 C CB  . ASN C 3 50  ? 133.070 95.209  121.442 1.00 219.05 ? 50  ASN B CB  1 
ATOM 6641 C CG  . ASN C 3 50  ? 134.028 96.306  121.863 1.00 218.39 ? 50  ASN B CG  1 
ATOM 6642 O OD1 . ASN C 3 50  ? 135.036 96.554  121.201 1.00 219.59 ? 50  ASN B OD1 1 
ATOM 6643 N ND2 . ASN C 3 50  ? 133.719 96.965  122.973 1.00 217.68 ? 50  ASN B ND2 1 
ATOM 6644 N N   . GLY C 3 51  ? 132.683 92.356  119.297 1.00 214.59 ? 51  GLY B N   1 
ATOM 6645 C CA  . GLY C 3 51  ? 131.799 91.215  119.116 1.00 213.28 ? 51  GLY B CA  1 
ATOM 6646 C C   . GLY C 3 51  ? 130.373 91.575  119.478 1.00 214.55 ? 51  GLY B C   1 
ATOM 6647 O O   . GLY C 3 51  ? 129.877 92.658  119.146 1.00 215.43 ? 51  GLY B O   1 
ATOM 6648 N N   . CYS C 3 52  ? 129.697 90.662  120.167 1.00 207.01 ? 52  CYS B N   1 
ATOM 6649 C CA  . CYS C 3 52  ? 128.368 90.947  120.682 1.00 205.95 ? 52  CYS B CA  1 
ATOM 6650 C C   . CYS C 3 52  ? 128.461 91.911  121.856 1.00 203.74 ? 52  CYS B C   1 
ATOM 6651 O O   . CYS C 3 52  ? 129.345 91.793  122.709 1.00 202.14 ? 52  CYS B O   1 
ATOM 6652 C CB  . CYS C 3 52  ? 127.669 89.658  121.115 1.00 205.53 ? 52  CYS B CB  1 
ATOM 6653 S SG  . CYS C 3 52  ? 126.827 88.776  119.782 1.00 208.07 ? 52  CYS B SG  1 
ATOM 6654 N N   . SER C 3 53  ? 127.542 92.871  121.893 1.00 199.23 ? 53  SER B N   1 
ATOM 6655 C CA  . SER C 3 53  ? 127.485 93.832  122.982 1.00 199.27 ? 53  SER B CA  1 
ATOM 6656 C C   . SER C 3 53  ? 126.026 94.097  123.315 1.00 201.25 ? 53  SER B C   1 
ATOM 6657 O O   . SER C 3 53  ? 125.136 93.906  122.482 1.00 202.64 ? 53  SER B O   1 
ATOM 6658 C CB  . SER C 3 53  ? 128.209 95.136  122.627 1.00 197.57 ? 53  SER B CB  1 
ATOM 6659 O OG  . SER C 3 53  ? 127.938 96.146  123.583 1.00 196.28 ? 53  SER B OG  1 
ATOM 6660 N N   . ARG C 3 54  ? 125.792 94.540  124.551 1.00 195.73 ? 54  ARG B N   1 
ATOM 6661 C CA  . ARG C 3 54  ? 124.445 94.767  125.071 1.00 194.86 ? 54  ARG B CA  1 
ATOM 6662 C C   . ARG C 3 54  ? 123.609 93.489  124.972 1.00 195.62 ? 54  ARG B C   1 
ATOM 6663 O O   . ARG C 3 54  ? 122.630 93.405  124.227 1.00 195.28 ? 54  ARG B O   1 
ATOM 6664 C CB  . ARG C 3 54  ? 123.764 95.938  124.353 1.00 193.96 ? 54  ARG B CB  1 
ATOM 6665 N N   . CYS C 3 55  ? 124.037 92.481  125.730 1.00 179.14 ? 55  CYS B N   1 
ATOM 6666 C CA  . CYS C 3 55  ? 123.335 91.205  125.769 1.00 177.32 ? 55  CYS B CA  1 
ATOM 6667 C C   . CYS C 3 55  ? 121.882 91.416  126.177 1.00 177.17 ? 55  CYS B C   1 
ATOM 6668 O O   . CYS C 3 55  ? 121.592 92.138  127.135 1.00 178.42 ? 55  CYS B O   1 
ATOM 6669 C CB  . CYS C 3 55  ? 124.036 90.261  126.746 1.00 175.81 ? 55  CYS B CB  1 
ATOM 6670 S SG  . CYS C 3 55  ? 124.011 88.517  126.289 1.00 180.40 ? 55  CYS B SG  1 
ATOM 6671 N N   . GLN C 3 56  ? 120.969 90.785  125.446 1.00 166.86 ? 56  GLN B N   1 
ATOM 6672 C CA  . GLN C 3 56  ? 119.549 91.081  125.559 1.00 169.12 ? 56  GLN B CA  1 
ATOM 6673 C C   . GLN C 3 56  ? 118.845 90.094  126.482 1.00 168.27 ? 56  GLN B C   1 
ATOM 6674 O O   . GLN C 3 56  ? 119.256 88.939  126.623 1.00 168.13 ? 56  GLN B O   1 
ATOM 6675 C CB  . GLN C 3 56  ? 118.883 91.066  124.179 1.00 169.82 ? 56  GLN B CB  1 
ATOM 6676 C CG  . GLN C 3 56  ? 118.024 89.840  123.883 1.00 167.92 ? 56  GLN B CG  1 
ATOM 6677 C CD  . GLN C 3 56  ? 118.840 88.594  123.599 1.00 167.06 ? 56  GLN B CD  1 
ATOM 6678 O OE1 . GLN C 3 56  ? 120.067 88.605  123.688 1.00 168.00 ? 56  GLN B OE1 1 
ATOM 6679 N NE2 . GLN C 3 56  ? 118.159 87.508  123.256 1.00 165.63 ? 56  GLN B NE2 1 
ATOM 6680 N N   . GLN C 3 57  ? 117.775 90.607  127.096 1.00 153.15 ? 57  GLN B N   1 
ATOM 6681 C CA  . GLN C 3 57  ? 116.891 89.767  127.939 1.00 150.93 ? 57  GLN B CA  1 
ATOM 6682 C C   . GLN C 3 57  ? 117.508 88.732  128.871 1.00 152.72 ? 57  GLN B C   1 
ATOM 6683 O O   . GLN C 3 57  ? 118.339 89.106  129.719 1.00 151.41 ? 57  GLN B O   1 
ATOM 6684 C CB  . GLN C 3 57  ? 116.075 88.833  127.040 1.00 150.17 ? 57  GLN B CB  1 
ATOM 6685 N N   . LYS C 3 58  ? 117.229 87.407  128.764 1.00 145.94 ? 58  LYS B N   1 
ATOM 6686 C CA  . LYS C 3 58  ? 117.655 86.359  129.733 1.00 146.14 ? 58  LYS B CA  1 
ATOM 6687 C C   . LYS C 3 58  ? 119.119 85.962  129.524 1.00 146.52 ? 58  LYS B C   1 
ATOM 6688 O O   . LYS C 3 58  ? 119.689 85.328  130.434 1.00 146.24 ? 58  LYS B O   1 
ATOM 6689 C CB  . LYS C 3 58  ? 116.810 85.098  129.525 1.00 142.81 ? 58  LYS B CB  1 
ATOM 6690 C CG  . LYS C 3 58  ? 115.494 85.062  130.271 1.00 139.68 ? 58  LYS B CG  1 
ATOM 6691 C CD  . LYS C 3 58  ? 114.394 85.942  129.698 1.00 142.27 ? 58  LYS B CD  1 
ATOM 6692 C CE  . LYS C 3 58  ? 113.883 86.889  130.728 1.00 142.83 ? 58  LYS B CE  1 
ATOM 6693 N NZ  . LYS C 3 58  ? 114.785 88.032  130.870 1.00 143.46 ? 58  LYS B NZ  1 
ATOM 6694 N N   . LEU C 3 59  ? 119.696 86.268  128.365 1.00 146.59 ? 59  LEU B N   1 
ATOM 6695 C CA  . LEU C 3 59  ? 121.093 85.983  128.085 1.00 143.03 ? 59  LEU B CA  1 
ATOM 6696 C C   . LEU C 3 59  ? 122.214 86.495  128.987 1.00 144.61 ? 59  LEU B C   1 
ATOM 6697 O O   . LEU C 3 59  ? 122.050 87.451  129.749 1.00 144.71 ? 59  LEU B O   1 
ATOM 6698 C CB  . LEU C 3 59  ? 121.364 86.351  126.627 1.00 146.14 ? 59  LEU B CB  1 
ATOM 6699 C CG  . LEU C 3 59  ? 120.995 85.339  125.542 1.00 143.28 ? 59  LEU B CG  1 
ATOM 6700 C CD1 . LEU C 3 59  ? 122.080 84.293  125.415 1.00 141.62 ? 59  LEU B CD1 1 
ATOM 6701 C CD2 . LEU C 3 59  ? 119.651 84.687  125.827 1.00 140.43 ? 59  LEU B CD2 1 
ATOM 6702 N N   . PHE C 3 60  ? 123.371 85.802  128.996 1.00 143.25 ? 60  PHE B N   1 
ATOM 6703 C CA  . PHE C 3 60  ? 124.523 86.200  129.868 1.00 140.54 ? 60  PHE B CA  1 
ATOM 6704 C C   . PHE C 3 60  ? 125.700 86.655  129.015 1.00 140.05 ? 60  PHE B C   1 
ATOM 6705 O O   . PHE C 3 60  ? 126.266 85.866  128.272 1.00 141.82 ? 60  PHE B O   1 
ATOM 6706 C CB  . PHE C 3 60  ? 125.186 85.211  130.832 1.00 138.13 ? 60  PHE B CB  1 
ATOM 6707 C CG  . PHE C 3 60  ? 124.345 84.774  132.018 1.00 138.24 ? 60  PHE B CG  1 
ATOM 6708 C CD1 . PHE C 3 60  ? 124.476 85.394  133.251 1.00 138.86 ? 60  PHE B CD1 1 
ATOM 6709 C CD2 . PHE C 3 60  ? 123.460 83.716  131.901 1.00 137.77 ? 60  PHE B CD2 1 
ATOM 6710 C CE1 . PHE C 3 60  ? 123.718 84.981  134.333 1.00 139.15 ? 60  PHE B CE1 1 
ATOM 6711 C CE2 . PHE C 3 60  ? 122.715 83.299  132.986 1.00 138.79 ? 60  PHE B CE2 1 
ATOM 6712 C CZ  . PHE C 3 60  ? 122.842 83.934  134.198 1.00 141.34 ? 60  PHE B CZ  1 
ATOM 6713 N N   . PHE C 3 61  ? 126.153 87.878  129.222 1.00 153.38 ? 61  PHE B N   1 
ATOM 6714 C CA  . PHE C 3 61  ? 127.257 88.497  128.502 1.00 156.56 ? 61  PHE B CA  1 
ATOM 6715 C C   . PHE C 3 61  ? 128.586 87.965  129.022 1.00 156.85 ? 61  PHE B C   1 
ATOM 6716 O O   . PHE C 3 61  ? 128.864 88.033  130.223 1.00 157.49 ? 61  PHE B O   1 
ATOM 6717 C CB  . PHE C 3 61  ? 127.193 90.015  128.666 1.00 156.52 ? 61  PHE B CB  1 
ATOM 6718 C CG  . PHE C 3 61  ? 128.351 90.745  128.047 1.00 156.43 ? 61  PHE B CG  1 
ATOM 6719 C CD1 . PHE C 3 61  ? 128.827 90.391  126.795 1.00 156.85 ? 61  PHE B CD1 1 
ATOM 6720 C CD2 . PHE C 3 61  ? 128.966 91.786  128.722 1.00 154.30 ? 61  PHE B CD2 1 
ATOM 6721 C CE1 . PHE C 3 61  ? 129.892 91.064  126.228 1.00 156.34 ? 61  PHE B CE1 1 
ATOM 6722 C CE2 . PHE C 3 61  ? 130.032 92.461  128.160 1.00 155.78 ? 61  PHE B CE2 1 
ATOM 6723 C CZ  . PHE C 3 61  ? 130.495 92.100  126.912 1.00 157.38 ? 61  PHE B CZ  1 
ATOM 6724 N N   . PHE C 3 62  ? 129.409 87.440  128.117 1.00 155.94 ? 62  PHE B N   1 
ATOM 6725 C CA  . PHE C 3 62  ? 130.698 86.868  128.476 1.00 155.80 ? 62  PHE B CA  1 
ATOM 6726 C C   . PHE C 3 62  ? 131.790 87.511  127.636 1.00 159.37 ? 62  PHE B C   1 
ATOM 6727 O O   . PHE C 3 62  ? 131.665 87.607  126.414 1.00 161.53 ? 62  PHE B O   1 
ATOM 6728 C CB  . PHE C 3 62  ? 130.701 85.351  128.272 1.00 155.95 ? 62  PHE B CB  1 
ATOM 6729 C CG  . PHE C 3 62  ? 132.035 84.708  128.510 1.00 155.87 ? 62  PHE B CG  1 
ATOM 6730 C CD1 . PHE C 3 62  ? 132.731 84.940  129.684 1.00 156.78 ? 62  PHE B CD1 1 
ATOM 6731 C CD2 . PHE C 3 62  ? 132.589 83.866  127.563 1.00 155.80 ? 62  PHE B CD2 1 
ATOM 6732 C CE1 . PHE C 3 62  ? 133.957 84.346  129.906 1.00 157.67 ? 62  PHE B CE1 1 
ATOM 6733 C CE2 . PHE C 3 62  ? 133.814 83.269  127.780 1.00 156.49 ? 62  PHE B CE2 1 
ATOM 6734 C CZ  . PHE C 3 62  ? 134.499 83.510  128.953 1.00 157.63 ? 62  PHE B CZ  1 
ATOM 6735 N N   . LEU C 3 63  ? 132.865 87.935  128.292 1.00 175.78 ? 63  LEU B N   1 
ATOM 6736 C CA  . LEU C 3 63  ? 133.982 88.609  127.641 1.00 174.82 ? 63  LEU B CA  1 
ATOM 6737 C C   . LEU C 3 63  ? 135.139 87.636  127.474 1.00 174.58 ? 63  LEU B C   1 
ATOM 6738 O O   . LEU C 3 63  ? 135.705 87.170  128.469 1.00 173.83 ? 63  LEU B O   1 
ATOM 6739 C CB  . LEU C 3 63  ? 134.343 89.896  128.383 1.00 172.88 ? 63  LEU B CB  1 
ATOM 6740 C CG  . LEU C 3 63  ? 134.898 91.073  127.581 1.00 173.20 ? 63  LEU B CG  1 
ATOM 6741 C CD1 . LEU C 3 63  ? 134.353 91.070  126.164 1.00 172.86 ? 63  LEU B CD1 1 
ATOM 6742 C CD2 . LEU C 3 63  ? 134.586 92.387  128.280 1.00 173.16 ? 63  LEU B CD2 1 
ATOM 6743 N N   . ARG C 3 64  ? 135.496 87.327  126.227 1.00 189.92 ? 64  ARG B N   1 
ATOM 6744 C CA  . ARG C 3 64  ? 136.654 86.507  125.946 1.00 190.77 ? 64  ARG B CA  1 
ATOM 6745 C C   . ARG C 3 64  ? 137.814 86.940  125.075 1.00 192.36 ? 64  ARG B C   1 
ATOM 6746 O O   . ARG C 3 64  ? 137.615 87.683  124.106 1.00 192.36 ? 64  ARG B O   1 
ATOM 6747 C CB  . ARG C 3 64  ? 136.060 85.212  125.355 1.00 189.61 ? 64  ARG B CB  1 
ATOM 6748 C CG  . ARG C 3 64  ? 137.054 84.099  125.068 1.00 190.38 ? 64  ARG B CG  1 
ATOM 6749 C CD  . ARG C 3 64  ? 136.359 82.898  124.445 1.00 189.55 ? 64  ARG B CD  1 
ATOM 6750 N NE  . ARG C 3 64  ? 135.796 83.179  123.130 1.00 190.66 ? 64  ARG B NE  1 
ATOM 6751 C CZ  . ARG C 3 64  ? 134.872 82.454  122.517 1.00 191.91 ? 64  ARG B CZ  1 
ATOM 6752 N NH1 . ARG C 3 64  ? 134.312 81.404  123.097 1.00 192.96 ? 64  ARG B NH1 1 
ATOM 6753 N NH2 . ARG C 3 64  ? 134.492 82.797  121.293 1.00 191.21 ? 64  ARG B NH2 1 
ATOM 6754 N N   . ARG C 3 65  ? 139.028 86.542  125.458 1.00 210.83 ? 65  ARG B N   1 
ATOM 6755 C CA  . ARG C 3 65  ? 140.254 87.063  124.899 1.00 211.13 ? 65  ARG B CA  1 
ATOM 6756 C C   . ARG C 3 65  ? 141.083 86.136  124.045 1.00 211.71 ? 65  ARG B C   1 
ATOM 6757 O O   . ARG C 3 65  ? 141.333 84.991  124.437 1.00 211.35 ? 65  ARG B O   1 
ATOM 6758 C CB  . ARG C 3 65  ? 141.223 87.521  125.997 1.00 210.43 ? 65  ARG B CB  1 
ATOM 6759 C CG  . ARG C 3 65  ? 140.661 88.619  126.891 1.00 209.43 ? 65  ARG B CG  1 
ATOM 6760 C CD  . ARG C 3 65  ? 141.640 89.025  127.979 1.00 209.39 ? 65  ARG B CD  1 
ATOM 6761 N NE  . ARG C 3 65  ? 142.823 89.681  127.433 1.00 209.99 ? 65  ARG B NE  1 
ATOM 6762 C CZ  . ARG C 3 65  ? 144.045 89.171  127.469 1.00 210.09 ? 65  ARG B CZ  1 
ATOM 6763 N NH1 . ARG C 3 65  ? 144.287 87.992  128.018 1.00 209.80 ? 65  ARG B NH1 1 
ATOM 6764 N NH2 . ARG C 3 65  ? 145.051 89.862  126.939 1.00 209.43 ? 65  ARG B NH2 1 
ATOM 6765 N N   . GLU C 3 66  ? 141.456 86.604  122.858 1.00 224.56 ? 66  GLU B N   1 
ATOM 6766 C CA  . GLU C 3 66  ? 142.436 85.952  121.997 1.00 224.34 ? 66  GLU B CA  1 
ATOM 6767 C C   . GLU C 3 66  ? 143.629 86.894  121.890 1.00 224.60 ? 66  GLU B C   1 
ATOM 6768 O O   . GLU C 3 66  ? 143.556 87.925  121.208 1.00 224.65 ? 66  GLU B O   1 
ATOM 6769 C CB  . GLU C 3 66  ? 141.940 85.523  120.618 1.00 223.64 ? 66  GLU B CB  1 
ATOM 6770 C CG  . GLU C 3 66  ? 140.696 84.652  120.645 1.00 224.42 ? 66  GLU B CG  1 
ATOM 6771 C CD  . GLU C 3 66  ? 140.803 83.514  121.642 1.00 224.64 ? 66  GLU B CD  1 
ATOM 6772 O OE1 . GLU C 3 66  ? 141.739 82.697  121.513 1.00 224.77 ? 66  GLU B OE1 1 
ATOM 6773 O OE2 . GLU C 3 66  ? 139.951 83.436  122.551 1.00 224.51 ? 66  GLU B OE2 1 
ATOM 6774 N N   . GLY C 3 67  ? 144.717 86.548  122.575 1.00 231.53 ? 67  GLY B N   1 
ATOM 6775 C CA  . GLY C 3 67  ? 145.882 87.418  122.598 1.00 231.16 ? 67  GLY B CA  1 
ATOM 6776 C C   . GLY C 3 67  ? 145.518 88.791  123.125 1.00 231.95 ? 67  GLY B C   1 
ATOM 6777 O O   . GLY C 3 67  ? 144.828 88.932  124.141 1.00 231.71 ? 67  GLY B O   1 
ATOM 6778 N N   . MET C 3 68  ? 145.990 89.825  122.426 1.00 236.17 ? 68  MET B N   1 
ATOM 6779 C CA  . MET C 3 68  ? 145.589 91.187  122.759 1.00 236.53 ? 68  MET B CA  1 
ATOM 6780 C C   . MET C 3 68  ? 144.119 91.528  122.553 1.00 236.57 ? 68  MET B C   1 
ATOM 6781 O O   . MET C 3 68  ? 143.464 92.059  123.458 1.00 236.35 ? 68  MET B O   1 
ATOM 6782 C CB  . MET C 3 68  ? 146.449 92.181  121.970 1.00 235.70 ? 68  MET B CB  1 
ATOM 6783 C CG  . MET C 3 68  ? 146.740 93.527  122.650 1.00 236.16 ? 68  MET B CG  1 
ATOM 6784 S SD  . MET C 3 68  ? 145.394 94.394  123.484 1.00 237.26 ? 68  MET B SD  1 
ATOM 6785 C CE  . MET C 3 68  ? 144.279 94.720  122.116 1.00 234.07 ? 68  MET B CE  1 
ATOM 6786 N N   . ARG C 3 69  ? 143.572 91.193  121.386 1.00 226.13 ? 69  ARG B N   1 
ATOM 6787 C CA  . ARG C 3 69  ? 142.178 91.551  121.109 1.00 225.40 ? 69  ARG B CA  1 
ATOM 6788 C C   . ARG C 3 69  ? 141.239 90.696  121.931 1.00 225.07 ? 69  ARG B C   1 
ATOM 6789 O O   . ARG C 3 69  ? 141.650 89.679  122.487 1.00 225.62 ? 69  ARG B O   1 
ATOM 6790 C CB  . ARG C 3 69  ? 141.891 91.399  119.615 1.00 223.76 ? 69  ARG B CB  1 
ATOM 6791 C CG  . ARG C 3 69  ? 142.082 89.989  119.085 1.00 222.65 ? 69  ARG B CG  1 
ATOM 6792 C CD  . ARG C 3 69  ? 141.779 89.918  117.597 1.00 222.74 ? 69  ARG B CD  1 
ATOM 6793 N NE  . ARG C 3 69  ? 140.378 90.197  117.307 1.00 223.58 ? 69  ARG B NE  1 
ATOM 6794 C CZ  . ARG C 3 69  ? 139.407 89.294  117.348 1.00 223.87 ? 69  ARG B CZ  1 
ATOM 6795 N NH1 . ARG C 3 69  ? 139.648 88.032  117.663 1.00 223.73 ? 69  ARG B NH1 1 
ATOM 6796 N NH2 . ARG C 3 69  ? 138.163 89.667  117.064 1.00 224.29 ? 69  ARG B NH2 1 
ATOM 6797 N N   . GLN C 3 70  ? 139.985 91.122  122.048 1.00 209.28 ? 70  GLN B N   1 
ATOM 6798 C CA  . GLN C 3 70  ? 139.000 90.372  122.815 1.00 208.18 ? 70  GLN B CA  1 
ATOM 6799 C C   . GLN C 3 70  ? 137.643 90.756  122.252 1.00 207.95 ? 70  GLN B C   1 
ATOM 6800 O O   . GLN C 3 70  ? 137.515 91.738  121.516 1.00 208.21 ? 70  GLN B O   1 
ATOM 6801 C CB  . GLN C 3 70  ? 139.133 90.866  124.259 1.00 207.23 ? 70  GLN B CB  1 
ATOM 6802 C CG  . GLN C 3 70  ? 138.420 92.183  124.521 1.00 205.67 ? 70  GLN B CG  1 
ATOM 6803 C CD  . GLN C 3 70  ? 138.839 92.829  125.823 1.00 206.02 ? 70  GLN B CD  1 
ATOM 6804 O OE1 . GLN C 3 70  ? 139.688 92.308  126.542 1.00 207.27 ? 70  GLN B OE1 1 
ATOM 6805 N NE2 . GLN C 3 70  ? 138.242 93.974  126.134 1.00 204.99 ? 70  GLN B NE2 1 
ATOM 6806 N N   . TYR C 3 71  ? 136.621 89.958  122.581 1.00 199.60 ? 71  TYR B N   1 
ATOM 6807 C CA  . TYR C 3 71  ? 135.249 90.169  122.052 1.00 199.36 ? 71  TYR B CA  1 
ATOM 6808 C C   . TYR C 3 71  ? 134.293 89.343  122.897 1.00 198.02 ? 71  TYR B C   1 
ATOM 6809 O O   . TYR C 3 71  ? 134.742 88.275  123.334 1.00 197.24 ? 71  TYR B O   1 
ATOM 6810 C CB  . TYR C 3 71  ? 135.208 89.778  120.574 1.00 199.25 ? 71  TYR B CB  1 
ATOM 6811 C CG  . TYR C 3 71  ? 135.767 88.384  120.340 1.00 198.00 ? 71  TYR B CG  1 
ATOM 6812 C CD1 . TYR C 3 71  ? 134.922 87.287  120.294 1.00 198.08 ? 71  TYR B CD1 1 
ATOM 6813 C CD2 . TYR C 3 71  ? 137.133 88.160  120.214 1.00 197.25 ? 71  TYR B CD2 1 
ATOM 6814 C CE1 . TYR C 3 71  ? 135.415 86.009  120.104 1.00 199.07 ? 71  TYR B CE1 1 
ATOM 6815 C CE2 . TYR C 3 71  ? 137.639 86.885  120.031 1.00 197.61 ? 71  TYR B CE2 1 
ATOM 6816 C CZ  . TYR C 3 71  ? 136.777 85.807  119.971 1.00 199.24 ? 71  TYR B CZ  1 
ATOM 6817 O OH  . TYR C 3 71  ? 137.267 84.548  119.787 1.00 199.20 ? 71  TYR B OH  1 
ATOM 6818 N N   . GLY C 3 72  ? 133.014 89.713  122.989 1.00 185.60 ? 72  GLY B N   1 
ATOM 6819 C CA  . GLY C 3 72  ? 132.014 89.105  123.839 1.00 184.32 ? 72  GLY B CA  1 
ATOM 6820 C C   . GLY C 3 72  ? 130.975 88.269  123.123 1.00 184.30 ? 72  GLY B C   1 
ATOM 6821 O O   . GLY C 3 72  ? 130.701 88.459  121.935 1.00 185.12 ? 72  GLY B O   1 
ATOM 6822 N N   . GLU C 3 73  ? 130.391 87.335  123.865 1.00 171.79 ? 73  GLU B N   1 
ATOM 6823 C CA  . GLU C 3 73  ? 129.354 86.445  123.373 1.00 171.47 ? 73  GLU B CA  1 
ATOM 6824 C C   . GLU C 3 73  ? 128.175 86.466  124.336 1.00 171.40 ? 73  GLU B C   1 
ATOM 6825 O O   . GLU C 3 73  ? 128.282 86.926  125.477 1.00 171.33 ? 73  GLU B O   1 
ATOM 6826 C CB  . GLU C 3 73  ? 129.873 85.009  123.206 1.00 170.24 ? 73  GLU B CB  1 
ATOM 6827 C CG  . GLU C 3 73  ? 131.293 84.918  122.670 1.00 170.93 ? 73  GLU B CG  1 
ATOM 6828 C CD  . GLU C 3 73  ? 131.896 83.538  122.843 1.00 172.47 ? 73  GLU B CD  1 
ATOM 6829 O OE1 . GLU C 3 73  ? 131.739 82.701  121.931 1.00 172.12 ? 73  GLU B OE1 1 
ATOM 6830 O OE2 . GLU C 3 73  ? 132.530 83.292  123.890 1.00 174.41 ? 73  GLU B OE2 1 
ATOM 6831 N N   . CYS C 3 74  ? 127.037 85.973  123.856 1.00 164.05 ? 74  CYS B N   1 
ATOM 6832 C CA  . CYS C 3 74  ? 125.809 85.896  124.643 1.00 163.94 ? 74  CYS B CA  1 
ATOM 6833 C C   . CYS C 3 74  ? 125.442 84.425  124.812 1.00 163.28 ? 74  CYS B C   1 
ATOM 6834 O O   . CYS C 3 74  ? 124.912 83.799  123.889 1.00 164.14 ? 74  CYS B O   1 
ATOM 6835 C CB  . CYS C 3 74  ? 124.687 86.689  123.980 1.00 164.20 ? 74  CYS B CB  1 
ATOM 6836 S SG  . CYS C 3 74  ? 124.694 88.455  124.379 1.00 164.76 ? 74  CYS B SG  1 
ATOM 6837 N N   . LEU C 3 75  ? 125.718 83.883  125.997 1.00 142.78 ? 75  LEU B N   1 
ATOM 6838 C CA  . LEU C 3 75  ? 125.453 82.488  126.324 1.00 142.72 ? 75  LEU B CA  1 
ATOM 6839 C C   . LEU C 3 75  ? 124.616 82.406  127.593 1.00 144.82 ? 75  LEU B C   1 
ATOM 6840 O O   . LEU C 3 75  ? 124.692 83.280  128.460 1.00 144.49 ? 75  LEU B O   1 
ATOM 6841 C CB  . LEU C 3 75  ? 126.755 81.698  126.531 1.00 140.68 ? 75  LEU B CB  1 
ATOM 6842 C CG  . LEU C 3 75  ? 127.797 81.600  125.416 1.00 143.10 ? 75  LEU B CG  1 
ATOM 6843 C CD1 . LEU C 3 75  ? 128.660 80.370  125.630 1.00 143.43 ? 75  LEU B CD1 1 
ATOM 6844 C CD2 . LEU C 3 75  ? 127.141 81.542  124.049 1.00 144.34 ? 75  LEU B CD2 1 
ATOM 6845 N N   . HIS C 3 76  ? 123.814 81.342  127.700 1.00 132.83 ? 76  HIS B N   1 
ATOM 6846 C CA  . HIS C 3 76  ? 123.084 81.098  128.941 1.00 132.19 ? 76  HIS B CA  1 
ATOM 6847 C C   . HIS C 3 76  ? 123.974 80.415  129.971 1.00 132.69 ? 76  HIS B C   1 
ATOM 6848 O O   . HIS C 3 76  ? 124.232 80.961  131.049 1.00 133.97 ? 76  HIS B O   1 
ATOM 6849 C CB  . HIS C 3 76  ? 121.845 80.234  128.690 1.00 127.24 ? 76  HIS B CB  1 
ATOM 6850 C CG  . HIS C 3 76  ? 121.296 80.336  127.304 1.00 129.51 ? 76  HIS B CG  1 
ATOM 6851 N ND1 . HIS C 3 76  ? 120.941 81.536  126.727 1.00 133.54 ? 76  HIS B ND1 1 
ATOM 6852 C CD2 . HIS C 3 76  ? 121.025 79.381  126.385 1.00 129.39 ? 76  HIS B CD2 1 
ATOM 6853 C CE1 . HIS C 3 76  ? 120.481 81.315  125.509 1.00 131.99 ? 76  HIS B CE1 1 
ATOM 6854 N NE2 . HIS C 3 76  ? 120.522 80.016  125.277 1.00 132.31 ? 76  HIS B NE2 1 
ATOM 6855 N N   . SER C 3 77  ? 124.451 79.216  129.653 1.00 142.56 ? 77  SER B N   1 
ATOM 6856 C CA  . SER C 3 77  ? 125.296 78.467  130.574 1.00 143.60 ? 77  SER B CA  1 
ATOM 6857 C C   . SER C 3 77  ? 126.661 79.134  130.653 1.00 146.21 ? 77  SER B C   1 
ATOM 6858 O O   . SER C 3 77  ? 127.424 79.122  129.683 1.00 147.00 ? 77  SER B O   1 
ATOM 6859 C CB  . SER C 3 77  ? 125.420 77.016  130.119 1.00 144.09 ? 77  SER B CB  1 
ATOM 6860 O OG  . SER C 3 77  ? 126.374 76.319  130.902 1.00 145.20 ? 77  SER B OG  1 
ATOM 6861 N N   . CYS C 3 78  ? 126.962 79.728  131.799 1.00 160.42 ? 78  CYS B N   1 
ATOM 6862 C CA  . CYS C 3 78  ? 128.266 80.334  131.999 1.00 160.74 ? 78  CYS B CA  1 
ATOM 6863 C C   . CYS C 3 78  ? 129.341 79.254  131.911 1.00 163.40 ? 78  CYS B C   1 
ATOM 6864 O O   . CYS C 3 78  ? 129.166 78.166  132.477 1.00 163.62 ? 78  CYS B O   1 
ATOM 6865 C CB  . CYS C 3 78  ? 128.313 81.042  133.351 1.00 159.74 ? 78  CYS B CB  1 
ATOM 6866 S SG  . CYS C 3 78  ? 129.525 82.370  133.475 1.00 175.44 ? 78  CYS B SG  1 
ATOM 6867 N N   . PRO C 3 79  ? 130.450 79.500  131.209 1.00 156.84 ? 79  PRO B N   1 
ATOM 6868 C CA  . PRO C 3 79  ? 131.426 78.428  130.956 1.00 154.35 ? 79  PRO B CA  1 
ATOM 6869 C C   . PRO C 3 79  ? 132.107 77.908  132.213 1.00 156.95 ? 79  PRO B C   1 
ATOM 6870 O O   . PRO C 3 79  ? 131.891 78.428  133.312 1.00 157.93 ? 79  PRO B O   1 
ATOM 6871 C CB  . PRO C 3 79  ? 132.440 79.091  130.013 1.00 153.97 ? 79  PRO B CB  1 
ATOM 6872 C CG  . PRO C 3 79  ? 131.737 80.289  129.457 1.00 153.72 ? 79  PRO B CG  1 
ATOM 6873 C CD  . PRO C 3 79  ? 130.820 80.755  130.536 1.00 154.60 ? 79  PRO B CD  1 
ATOM 6874 N N   . SER C 3 80  ? 132.932 76.874  132.055 1.00 159.98 ? 80  SER B N   1 
ATOM 6875 C CA  . SER C 3 80  ? 133.650 76.308  133.189 1.00 160.64 ? 80  SER B CA  1 
ATOM 6876 C C   . SER C 3 80  ? 134.627 77.328  133.758 1.00 160.72 ? 80  SER B C   1 
ATOM 6877 O O   . SER C 3 80  ? 135.199 78.142  133.028 1.00 160.22 ? 80  SER B O   1 
ATOM 6878 C CB  . SER C 3 80  ? 134.393 75.041  132.767 1.00 158.93 ? 80  SER B CB  1 
ATOM 6879 O OG  . SER C 3 80  ? 133.532 73.915  132.793 1.00 158.85 ? 80  SER B OG  1 
ATOM 6880 N N   . GLY C 3 81  ? 134.774 77.331  135.087 1.00 159.90 ? 81  GLY B N   1 
ATOM 6881 C CA  . GLY C 3 81  ? 135.619 78.330  135.759 1.00 159.74 ? 81  GLY B CA  1 
ATOM 6882 C C   . GLY C 3 81  ? 134.920 79.670  135.712 1.00 160.25 ? 81  GLY B C   1 
ATOM 6883 O O   . GLY C 3 81  ? 135.629 80.695  135.803 1.00 159.77 ? 81  GLY B O   1 
ATOM 6884 N N   . TYR C 3 82  ? 133.594 79.672  135.561 1.00 152.15 ? 82  TYR B N   1 
ATOM 6885 C CA  . TYR C 3 82  ? 132.835 80.936  135.408 1.00 150.20 ? 82  TYR B CA  1 
ATOM 6886 C C   . TYR C 3 82  ? 131.422 80.746  135.939 1.00 152.06 ? 82  TYR B C   1 
ATOM 6887 O O   . TYR C 3 82  ? 130.847 79.670  135.674 1.00 152.78 ? 82  TYR B O   1 
ATOM 6888 C CB  . TYR C 3 82  ? 132.952 81.288  133.923 1.00 149.73 ? 82  TYR B CB  1 
ATOM 6889 C CG  . TYR C 3 82  ? 133.883 82.456  133.647 1.00 150.74 ? 82  TYR B CG  1 
ATOM 6890 C CD1 . TYR C 3 82  ? 135.173 82.246  133.181 1.00 152.26 ? 82  TYR B CD1 1 
ATOM 6891 C CD2 . TYR C 3 82  ? 133.474 83.762  133.864 1.00 151.27 ? 82  TYR B CD2 1 
ATOM 6892 C CE1 . TYR C 3 82  ? 136.028 83.304  132.930 1.00 153.99 ? 82  TYR B CE1 1 
ATOM 6893 C CE2 . TYR C 3 82  ? 134.322 84.829  133.626 1.00 155.12 ? 82  TYR B CE2 1 
ATOM 6894 C CZ  . TYR C 3 82  ? 135.603 84.599  133.162 1.00 156.63 ? 82  TYR B CZ  1 
ATOM 6895 O OH  . TYR C 3 82  ? 136.437 85.649  132.922 1.00 156.66 ? 82  TYR B OH  1 
ATOM 6896 N N   . TYR C 3 83  ? 130.899 81.726  136.703 1.00 137.62 ? 83  TYR B N   1 
ATOM 6897 C CA  . TYR C 3 83  ? 129.523 81.682  137.280 1.00 133.50 ? 83  TYR B CA  1 
ATOM 6898 C C   . TYR C 3 83  ? 128.754 82.909  136.823 1.00 134.62 ? 83  TYR B C   1 
ATOM 6899 O O   . TYR C 3 83  ? 129.308 84.002  136.880 1.00 140.73 ? 83  TYR B O   1 
ATOM 6900 C CB  . TYR C 3 83  ? 129.437 81.676  138.809 1.00 128.83 ? 83  TYR B CB  1 
ATOM 6901 C CG  . TYR C 3 83  ? 129.843 82.970  139.498 1.00 129.87 ? 83  TYR B CG  1 
ATOM 6902 C CD1 . TYR C 3 83  ? 131.173 83.253  139.778 1.00 134.89 ? 83  TYR B CD1 1 
ATOM 6903 C CD2 . TYR C 3 83  ? 128.889 83.913  139.856 1.00 130.89 ? 83  TYR B CD2 1 
ATOM 6904 C CE1 . TYR C 3 83  ? 131.539 84.436  140.397 1.00 138.99 ? 83  TYR B CE1 1 
ATOM 6905 C CE2 . TYR C 3 83  ? 129.243 85.101  140.470 1.00 133.55 ? 83  TYR B CE2 1 
ATOM 6906 C CZ  . TYR C 3 83  ? 130.573 85.362  140.741 1.00 138.58 ? 83  TYR B CZ  1 
ATOM 6907 O OH  . TYR C 3 83  ? 130.940 86.527  141.349 1.00 139.36 ? 83  TYR B OH  1 
ATOM 6908 N N   . GLY C 3 84  ? 127.476 82.770  136.485 1.00 125.18 ? 84  GLY B N   1 
ATOM 6909 C CA  . GLY C 3 84  ? 126.657 83.838  135.947 1.00 129.64 ? 84  GLY B CA  1 
ATOM 6910 C C   . GLY C 3 84  ? 125.919 84.594  137.033 1.00 129.49 ? 84  GLY B C   1 
ATOM 6911 O O   . GLY C 3 84  ? 125.295 83.991  137.910 1.00 131.79 ? 84  GLY B O   1 
ATOM 6912 N N   . HIS C 3 85  ? 125.994 85.918  136.967 1.00 131.65 ? 85  HIS B N   1 
ATOM 6913 C CA  . HIS C 3 85  ? 125.277 86.808  137.868 1.00 129.99 ? 85  HIS B CA  1 
ATOM 6914 C C   . HIS C 3 85  ? 124.185 87.519  137.083 1.00 130.66 ? 85  HIS B C   1 
ATOM 6915 O O   . HIS C 3 85  ? 124.437 88.035  135.989 1.00 132.83 ? 85  HIS B O   1 
ATOM 6916 C CB  . HIS C 3 85  ? 126.229 87.823  138.505 1.00 129.02 ? 85  HIS B CB  1 
ATOM 6917 C CG  . HIS C 3 85  ? 125.589 88.684  139.549 1.00 131.54 ? 85  HIS B CG  1 
ATOM 6918 N ND1 . HIS C 3 85  ? 124.622 89.621  139.254 1.00 134.18 ? 85  HIS B ND1 1 
ATOM 6919 C CD2 . HIS C 3 85  ? 125.779 88.749  140.888 1.00 132.15 ? 85  HIS B CD2 1 
ATOM 6920 C CE1 . HIS C 3 85  ? 124.244 90.226  140.366 1.00 132.25 ? 85  HIS B CE1 1 
ATOM 6921 N NE2 . HIS C 3 85  ? 124.931 89.715  141.372 1.00 133.01 ? 85  HIS B NE2 1 
ATOM 6922 N N   . ARG C 3 86  ? 122.979 87.545  137.641 1.00 118.22 ? 86  ARG B N   1 
ATOM 6923 C CA  . ARG C 3 86  ? 121.819 88.114  136.970 1.00 117.25 ? 86  ARG B CA  1 
ATOM 6924 C C   . ARG C 3 86  ? 121.498 89.482  137.556 1.00 118.11 ? 86  ARG B C   1 
ATOM 6925 O O   . ARG C 3 86  ? 121.426 89.639  138.779 1.00 119.76 ? 86  ARG B O   1 
ATOM 6926 C CB  . ARG C 3 86  ? 120.609 87.188  137.093 1.00 111.08 ? 86  ARG B CB  1 
ATOM 6927 C CG  . ARG C 3 86  ? 120.344 86.363  135.850 1.00 114.01 ? 86  ARG B CG  1 
ATOM 6928 C CD  . ARG C 3 86  ? 119.506 85.136  136.163 1.00 109.76 ? 86  ARG B CD  1 
ATOM 6929 N NE  . ARG C 3 86  ? 119.768 84.037  135.242 1.00 110.96 ? 86  ARG B NE  1 
ATOM 6930 C CZ  . ARG C 3 86  ? 119.375 84.007  133.976 1.00 113.82 ? 86  ARG B CZ  1 
ATOM 6931 N NH1 . ARG C 3 86  ? 118.710 85.013  133.434 1.00 116.30 ? 86  ARG B NH1 1 
ATOM 6932 N NH2 . ARG C 3 86  ? 119.656 82.939  133.235 1.00 113.39 ? 86  ARG B NH2 1 
ATOM 6933 N N   . ALA C 3 87  ? 121.311 90.463  136.680 1.00 132.78 ? 87  ALA B N   1 
ATOM 6934 C CA  . ALA C 3 87  ? 120.995 91.832  137.051 1.00 133.50 ? 87  ALA B CA  1 
ATOM 6935 C C   . ALA C 3 87  ? 119.955 92.368  136.080 1.00 136.37 ? 87  ALA B C   1 
ATOM 6936 O O   . ALA C 3 87  ? 119.853 91.878  134.949 1.00 139.42 ? 87  ALA B O   1 
ATOM 6937 C CB  . ALA C 3 87  ? 122.249 92.722  137.026 1.00 132.28 ? 87  ALA B CB  1 
ATOM 6938 N N   . PRO C 3 88  ? 119.158 93.359  136.492 1.00 135.43 ? 88  PRO B N   1 
ATOM 6939 C CA  . PRO C 3 88  ? 118.138 93.893  135.575 1.00 136.17 ? 88  PRO B CA  1 
ATOM 6940 C C   . PRO C 3 88  ? 118.802 94.550  134.381 1.00 139.59 ? 88  PRO B C   1 
ATOM 6941 O O   . PRO C 3 88  ? 118.242 94.522  133.278 1.00 139.50 ? 88  PRO B O   1 
ATOM 6942 C CB  . PRO C 3 88  ? 117.397 94.930  136.434 1.00 134.16 ? 88  PRO B CB  1 
ATOM 6943 C CG  . PRO C 3 88  ? 117.801 94.645  137.845 1.00 132.27 ? 88  PRO B CG  1 
ATOM 6944 C CD  . PRO C 3 88  ? 119.184 94.104  137.760 1.00 132.91 ? 88  PRO B CD  1 
ATOM 6945 N N   . ASP C 3 89  ? 119.963 95.168  134.598 1.00 151.11 ? 89  ASP B N   1 
ATOM 6946 C CA  . ASP C 3 89  ? 120.707 95.824  133.492 1.00 150.01 ? 89  ASP B CA  1 
ATOM 6947 C C   . ASP C 3 89  ? 121.180 94.751  132.517 1.00 150.23 ? 89  ASP B C   1 
ATOM 6948 O O   . ASP C 3 89  ? 120.548 94.608  131.460 1.00 149.67 ? 89  ASP B O   1 
ATOM 6949 C CB  . ASP C 3 89  ? 121.870 96.675  133.982 1.00 149.06 ? 89  ASP B CB  1 
ATOM 6950 C CG  . ASP C 3 89  ? 122.640 96.203  135.207 1.00 149.33 ? 89  ASP B CG  1 
ATOM 6951 O OD1 . ASP C 3 89  ? 122.051 96.211  136.305 1.00 148.72 ? 89  ASP B OD1 1 
ATOM 6952 O OD2 . ASP C 3 89  ? 123.826 95.848  135.053 1.00 150.65 ? 89  ASP B OD2 1 
ATOM 6953 N N   . MET C 3 90  ? 122.233 94.025  132.851 1.00 154.82 ? 90  MET B N   1 
ATOM 6954 C CA  . MET C 3 90  ? 122.810 92.988  132.021 1.00 154.33 ? 90  MET B CA  1 
ATOM 6955 C C   . MET C 3 90  ? 123.367 91.862  132.869 1.00 153.08 ? 90  MET B C   1 
ATOM 6956 O O   . MET C 3 90  ? 123.941 92.111  133.932 1.00 153.00 ? 90  MET B O   1 
ATOM 6957 C CB  . MET C 3 90  ? 123.972 93.647  131.267 1.00 154.87 ? 90  MET B CB  1 
ATOM 6958 C CG  . MET C 3 90  ? 125.114 94.122  132.150 1.00 155.85 ? 90  MET B CG  1 
ATOM 6959 S SD  . MET C 3 90  ? 126.262 95.206  131.281 1.00 163.08 ? 90  MET B SD  1 
ATOM 6960 C CE  . MET C 3 90  ? 125.495 96.800  131.547 1.00 153.88 ? 90  MET B CE  1 
ATOM 6961 N N   . ASN C 3 91  ? 123.174 90.629  132.409 1.00 140.09 ? 91  ASN B N   1 
ATOM 6962 C CA  . ASN C 3 91  ? 123.611 89.448  133.137 1.00 139.03 ? 91  ASN B CA  1 
ATOM 6963 C C   . ASN C 3 91  ? 125.064 89.188  132.764 1.00 141.10 ? 91  ASN B C   1 
ATOM 6964 O O   . ASN C 3 91  ? 125.392 89.041  131.582 1.00 142.11 ? 91  ASN B O   1 
ATOM 6965 C CB  . ASN C 3 91  ? 122.754 88.210  132.882 1.00 137.68 ? 91  ASN B CB  1 
ATOM 6966 C CG  . ASN C 3 91  ? 121.279 88.533  132.799 1.00 139.24 ? 91  ASN B CG  1 
ATOM 6967 O OD1 . ASN C 3 91  ? 120.774 89.377  133.538 1.00 140.67 ? 91  ASN B OD1 1 
ATOM 6968 N ND2 . ASN C 3 91  ? 120.577 87.862  131.894 1.00 141.79 ? 91  ASN B ND2 1 
ATOM 6969 N N   . ARG C 3 92  ? 125.928 89.127  133.771 1.00 141.50 ? 92  ARG B N   1 
ATOM 6970 C CA  . ARG C 3 92  ? 127.365 89.019  133.568 1.00 140.31 ? 92  ARG B CA  1 
ATOM 6971 C C   . ARG C 3 92  ? 127.864 87.622  133.903 1.00 142.77 ? 92  ARG B C   1 
ATOM 6972 O O   . ARG C 3 92  ? 127.161 86.805  134.501 1.00 147.94 ? 92  ARG B O   1 
ATOM 6973 C CB  . ARG C 3 92  ? 128.099 90.050  134.432 1.00 139.95 ? 92  ARG B CB  1 
ATOM 6974 C CG  . ARG C 3 92  ? 127.845 91.489  134.026 1.00 140.73 ? 92  ARG B CG  1 
ATOM 6975 C CD  . ARG C 3 92  ? 128.562 92.458  134.951 1.00 144.26 ? 92  ARG B CD  1 
ATOM 6976 N NE  . ARG C 3 92  ? 128.346 93.846  134.561 1.00 147.26 ? 92  ARG B NE  1 
ATOM 6977 C CZ  . ARG C 3 92  ? 127.281 94.562  134.893 1.00 147.16 ? 92  ARG B CZ  1 
ATOM 6978 N NH1 . ARG C 3 92  ? 126.306 94.051  135.629 1.00 147.77 ? 92  ARG B NH1 1 
ATOM 6979 N NH2 . ARG C 3 92  ? 127.190 95.822  134.477 1.00 143.08 ? 92  ARG B NH2 1 
ATOM 6980 N N   . CYS C 3 93  ? 129.106 87.355  133.506 1.00 140.28 ? 93  CYS B N   1 
ATOM 6981 C CA  . CYS C 3 93  ? 129.793 86.112  133.828 1.00 140.01 ? 93  CYS B CA  1 
ATOM 6982 C C   . CYS C 3 93  ? 131.134 86.464  134.452 1.00 139.85 ? 93  CYS B C   1 
ATOM 6983 O O   . CYS C 3 93  ? 131.882 87.275  133.897 1.00 144.79 ? 93  CYS B O   1 
ATOM 6984 C CB  . CYS C 3 93  ? 129.988 85.225  132.594 1.00 142.33 ? 93  CYS B CB  1 
ATOM 6985 S SG  . CYS C 3 93  ? 128.753 83.913  132.406 1.00 152.03 ? 93  CYS B SG  1 
ATOM 6986 N N   . ALA C 3 94  ? 131.438 85.864  135.601 1.00 139.87 ? 94  ALA B N   1 
ATOM 6987 C CA  . ALA C 3 94  ? 132.654 86.194  136.330 1.00 142.01 ? 94  ALA B CA  1 
ATOM 6988 C C   . ALA C 3 94  ? 133.481 85.022  136.834 1.00 144.06 ? 94  ALA B C   1 
ATOM 6989 O O   . ALA C 3 94  ? 132.971 83.916  137.012 1.00 146.38 ? 94  ALA B O   1 
ATOM 6990 C CB  . ALA C 3 94  ? 132.355 87.050  137.567 1.00 138.92 ? 94  ALA B CB  1 
ATOM 6991 N N   . ARG C 3 95  ? 134.764 85.280  137.073 1.00 150.81 ? 95  ARG B N   1 
ATOM 6992 C CA  . ARG C 3 95  ? 135.640 84.218  137.571 1.00 151.09 ? 95  ARG B CA  1 
ATOM 6993 C C   . ARG C 3 95  ? 135.219 83.551  138.864 1.00 150.88 ? 95  ARG B C   1 
ATOM 6994 O O   . ARG C 3 95  ? 134.756 84.219  139.792 1.00 151.38 ? 95  ARG B O   1 
ATOM 6995 C CB  . ARG C 3 95  ? 137.042 84.772  137.818 1.00 152.32 ? 95  ARG B CB  1 
ATOM 6996 C CG  . ARG C 3 95  ? 138.062 83.738  138.256 1.00 151.44 ? 95  ARG B CG  1 
ATOM 6997 C CD  . ARG C 3 95  ? 138.309 82.722  137.155 1.00 152.33 ? 95  ARG B CD  1 
ATOM 6998 N NE  . ARG C 3 95  ? 138.924 83.329  135.981 1.00 155.18 ? 95  ARG B NE  1 
ATOM 6999 C CZ  . ARG C 3 95  ? 139.161 82.692  134.842 1.00 154.73 ? 95  ARG B CZ  1 
ATOM 7000 N NH1 . ARG C 3 95  ? 138.848 81.417  134.684 1.00 153.62 ? 95  ARG B NH1 1 
ATOM 7001 N NH2 . ARG C 3 95  ? 139.728 83.353  133.835 1.00 154.04 ? 95  ARG B NH2 1 
ATOM 7002 N N   . CYS C 3 96  ? 135.345 82.227  138.917 1.00 155.46 ? 96  CYS B N   1 
ATOM 7003 C CA  . CYS C 3 96  ? 134.997 81.488  140.124 1.00 156.84 ? 96  CYS B CA  1 
ATOM 7004 C C   . CYS C 3 96  ? 136.241 81.871  140.915 1.00 158.48 ? 96  CYS B C   1 
ATOM 7005 O O   . CYS C 3 96  ? 137.342 81.393  140.623 1.00 158.49 ? 96  CYS B O   1 
ATOM 7006 C CB  . CYS C 3 96  ? 134.975 79.963  140.048 1.00 158.47 ? 96  CYS B CB  1 
ATOM 7007 S SG  . CYS C 3 96  ? 133.653 79.262  139.038 1.00 172.83 ? 96  CYS B SG  1 
ATOM 7008 N N   . ARG C 3 97  ? 136.068 82.733  141.919 1.00 157.71 ? 97  ARG B N   1 
ATOM 7009 C CA  . ARG C 3 97  ? 137.207 83.065  142.778 1.00 158.53 ? 97  ARG B CA  1 
ATOM 7010 C C   . ARG C 3 97  ? 137.613 81.961  143.825 1.00 157.88 ? 97  ARG B C   1 
ATOM 7011 O O   . ARG C 3 97  ? 138.683 81.944  144.441 1.00 156.87 ? 97  ARG B O   1 
ATOM 7012 C CB  . ARG C 3 97  ? 136.852 84.257  143.666 1.00 156.36 ? 97  ARG B CB  1 
ATOM 7013 C CG  . ARG C 3 97  ? 136.555 85.591  142.943 1.00 155.91 ? 97  ARG B CG  1 
ATOM 7014 C CD  . ARG C 3 97  ? 137.713 86.279  142.184 1.00 157.92 ? 97  ARG B CD  1 
ATOM 7015 N NE  . ARG C 3 97  ? 137.377 87.545  141.542 1.00 160.81 ? 97  ARG B NE  1 
ATOM 7016 C CZ  . ARG C 3 97  ? 138.151 88.171  140.664 1.00 158.89 ? 97  ARG B CZ  1 
ATOM 7017 N NH1 . ARG C 3 97  ? 139.316 87.670  140.289 1.00 157.08 ? 97  ARG B NH1 1 
ATOM 7018 N NH2 . ARG C 3 97  ? 137.748 89.333  140.156 1.00 156.66 ? 97  ARG B NH2 1 
ATOM 7019 N N   . ILE C 3 98  ? 136.716 80.978  143.922 1.00 159.99 ? 98  ILE B N   1 
ATOM 7020 C CA  . ILE C 3 98  ? 137.023 79.755  144.649 1.00 159.09 ? 98  ILE B CA  1 
ATOM 7021 C C   . ILE C 3 98  ? 138.201 79.122  143.922 1.00 162.21 ? 98  ILE B C   1 
ATOM 7022 O O   . ILE C 3 98  ? 138.232 79.050  142.686 1.00 162.47 ? 98  ILE B O   1 
ATOM 7023 C CB  . ILE C 3 98  ? 135.896 78.732  144.875 1.00 157.36 ? 98  ILE B CB  1 
ATOM 7024 C CG1 . ILE C 3 98  ? 136.461 77.430  145.454 1.00 159.18 ? 98  ILE B CG1 1 
ATOM 7025 C CG2 . ILE C 3 98  ? 135.101 78.505  143.583 1.00 158.89 ? 98  ILE B CG2 1 
ATOM 7026 C CD1 . ILE C 3 98  ? 135.608 76.811  146.537 1.00 158.31 ? 98  ILE B CD1 1 
ATOM 7027 N N   . GLU C 3 99  ? 139.157 78.619  144.695 1.00 174.58 ? 99  GLU B N   1 
ATOM 7028 C CA  . GLU C 3 99  ? 140.312 77.895  144.126 1.00 173.40 ? 99  GLU B CA  1 
ATOM 7029 C C   . GLU C 3 99  ? 139.953 76.468  143.719 1.00 172.80 ? 99  GLU B C   1 
ATOM 7030 O O   . GLU C 3 99  ? 138.944 75.946  144.200 1.00 173.83 ? 99  GLU B O   1 
ATOM 7031 C CB  . GLU C 3 99  ? 141.416 77.804  145.176 1.00 173.13 ? 99  GLU B CB  1 
ATOM 7032 C CG  . GLU C 3 99  ? 141.258 76.689  146.209 1.00 173.21 ? 99  GLU B CG  1 
ATOM 7033 C CD  . GLU C 3 99  ? 139.931 76.665  146.943 1.00 173.26 ? 99  GLU B CD  1 
ATOM 7034 O OE1 . GLU C 3 99  ? 139.579 77.704  147.536 1.00 173.89 ? 99  GLU B OE1 1 
ATOM 7035 O OE2 . GLU C 3 99  ? 139.242 75.629  146.905 1.00 172.07 ? 99  GLU B OE2 1 
ATOM 7036 N N   . ASN C 3 100 ? 140.721 75.875  142.824 1.00 179.23 ? 100 ASN B N   1 
ATOM 7037 C CA  . ASN C 3 100 ? 140.589 74.466  142.456 1.00 181.95 ? 100 ASN B CA  1 
ATOM 7038 C C   . ASN C 3 100 ? 139.149 74.011  142.219 1.00 182.46 ? 100 ASN B C   1 
ATOM 7039 O O   . ASN C 3 100 ? 138.682 73.023  142.789 1.00 182.01 ? 100 ASN B O   1 
ATOM 7040 C CB  . ASN C 3 100 ? 141.204 73.740  143.655 1.00 182.34 ? 100 ASN B CB  1 
ATOM 7041 C CG  . ASN C 3 100 ? 141.959 72.495  143.251 1.00 183.53 ? 100 ASN B CG  1 
ATOM 7042 O OD1 . ASN C 3 100 ? 141.677 71.897  142.215 1.00 183.68 ? 100 ASN B OD1 1 
ATOM 7043 N ND2 . ASN C 3 100 ? 142.930 72.100  144.066 1.00 182.50 ? 100 ASN B ND2 1 
ATOM 7044 N N   . CYS C 3 101 ? 138.442 74.746  141.362 1.00 176.64 ? 101 CYS B N   1 
ATOM 7045 C CA  . CYS C 3 101 ? 137.055 74.444  141.041 1.00 175.18 ? 101 CYS B CA  1 
ATOM 7046 C C   . CYS C 3 101 ? 136.840 74.587  139.542 1.00 176.03 ? 101 CYS B C   1 
ATOM 7047 O O   . CYS C 3 101 ? 137.488 75.402  138.881 1.00 176.73 ? 101 CYS B O   1 
ATOM 7048 C CB  . CYS C 3 101 ? 136.091 75.363  141.804 1.00 176.11 ? 101 CYS B CB  1 
ATOM 7049 S SG  . CYS C 3 101 ? 134.341 75.008  141.534 1.00 186.17 ? 101 CYS B SG  1 
ATOM 7050 N N   . ASP C 3 102 ? 135.900 73.787  138.983 1.00 174.08 ? 102 ASP B N   1 
ATOM 7051 C CA  . ASP C 3 102 ? 135.606 73.733  137.516 1.00 173.78 ? 102 ASP B CA  1 
ATOM 7052 C C   . ASP C 3 102 ? 134.268 74.392  137.169 1.00 172.45 ? 102 ASP B C   1 
ATOM 7053 O O   . ASP C 3 102 ? 134.168 74.771  136.006 1.00 172.57 ? 102 ASP B O   1 
ATOM 7054 C CB  . ASP C 3 102 ? 135.518 72.305  137.004 1.00 173.35 ? 102 ASP B CB  1 
ATOM 7055 C CG  . ASP C 3 102 ? 136.452 71.290  137.644 1.00 174.65 ? 102 ASP B CG  1 
ATOM 7056 O OD1 . ASP C 3 102 ? 136.299 71.033  138.851 1.00 175.60 ? 102 ASP B OD1 1 
ATOM 7057 O OD2 . ASP C 3 102 ? 137.307 70.745  136.919 1.00 174.55 ? 102 ASP B OD2 1 
ATOM 7058 N N   . SER C 3 103 ? 133.210 74.242  137.970 1.00 149.62 ? 103 SER B N   1 
ATOM 7059 C CA  . SER C 3 103 ? 131.954 74.970  137.857 1.00 148.97 ? 103 SER B CA  1 
ATOM 7060 C C   . SER C 3 103 ? 131.490 75.351  139.252 1.00 148.75 ? 103 SER B C   1 
ATOM 7061 O O   . SER C 3 103 ? 131.447 74.501  140.147 1.00 151.58 ? 103 SER B O   1 
ATOM 7062 C CB  . SER C 3 103 ? 130.886 74.134  137.146 1.00 150.51 ? 103 SER B CB  1 
ATOM 7063 O OG  . SER C 3 103 ? 130.853 72.813  137.655 1.00 151.43 ? 103 SER B OG  1 
ATOM 7064 N N   . CYS C 3 104 ? 131.143 76.621  139.436 1.00 131.94 ? 104 CYS B N   1 
ATOM 7065 C CA  . CYS C 3 104 ? 130.780 77.148  140.742 1.00 131.40 ? 104 CYS B CA  1 
ATOM 7066 C C   . CYS C 3 104 ? 129.374 77.731  140.704 1.00 134.12 ? 104 CYS B C   1 
ATOM 7067 O O   . CYS C 3 104 ? 129.010 78.443  139.764 1.00 133.68 ? 104 CYS B O   1 
ATOM 7068 C CB  . CYS C 3 104 ? 131.786 78.212  141.199 1.00 134.26 ? 104 CYS B CB  1 
ATOM 7069 S SG  . CYS C 3 104 ? 131.962 79.631  140.097 1.00 148.17 ? 104 CYS B SG  1 
ATOM 7070 N N   . PHE C 3 105 ? 128.583 77.407  141.731 1.00 110.11 ? 105 PHE B N   1 
ATOM 7071 C CA  . PHE C 3 105 ? 127.243 77.976  141.854 1.00 104.24 ? 105 PHE B CA  1 
ATOM 7072 C C   . PHE C 3 105 ? 127.305 79.486  142.038 1.00 105.10 ? 105 PHE B C   1 
ATOM 7073 O O   . PHE C 3 105 ? 126.545 80.230  141.408 1.00 102.37 ? 105 PHE B O   1 
ATOM 7074 C CB  . PHE C 3 105 ? 126.509 77.313  143.023 1.00 105.24 ? 105 PHE B CB  1 
ATOM 7075 C CG  . PHE C 3 105 ? 125.217 77.987  143.406 1.00 99.00  ? 105 PHE B CG  1 
ATOM 7076 C CD1 . PHE C 3 105 ? 125.197 79.010  144.340 1.00 102.80 ? 105 PHE B CD1 1 
ATOM 7077 C CD2 . PHE C 3 105 ? 124.021 77.580  142.849 1.00 94.66  ? 105 PHE B CD2 1 
ATOM 7078 C CE1 . PHE C 3 105 ? 124.013 79.622  144.690 1.00 103.31 ? 105 PHE B CE1 1 
ATOM 7079 C CE2 . PHE C 3 105 ? 122.835 78.189  143.197 1.00 94.62  ? 105 PHE B CE2 1 
ATOM 7080 C CZ  . PHE C 3 105 ? 122.831 79.210  144.119 1.00 99.22  ? 105 PHE B CZ  1 
ATOM 7081 N N   . SER C 3 106 ? 128.203 79.954  142.898 1.00 120.28 ? 106 SER B N   1 
ATOM 7082 C CA  . SER C 3 106 ? 128.366 81.373  143.174 1.00 115.74 ? 106 SER B CA  1 
ATOM 7083 C C   . SER C 3 106 ? 129.841 81.631  143.455 1.00 122.48 ? 106 SER B C   1 
ATOM 7084 O O   . SER C 3 106 ? 130.676 80.727  143.359 1.00 125.85 ? 106 SER B O   1 
ATOM 7085 C CB  . SER C 3 106 ? 127.466 81.806  144.337 1.00 113.24 ? 106 SER B CB  1 
ATOM 7086 O OG  . SER C 3 106 ? 127.925 83.017  144.910 1.00 120.45 ? 106 SER B OG  1 
ATOM 7087 N N   . LYS C 3 107 ? 130.167 82.875  143.805 1.00 130.25 ? 107 LYS B N   1 
ATOM 7088 C CA  . LYS C 3 107 ? 131.558 83.230  144.053 1.00 129.65 ? 107 LYS B CA  1 
ATOM 7089 C C   . LYS C 3 107 ? 132.097 82.647  145.357 1.00 132.32 ? 107 LYS B C   1 
ATOM 7090 O O   . LYS C 3 107 ? 133.312 82.692  145.574 1.00 133.52 ? 107 LYS B O   1 
ATOM 7091 C CB  . LYS C 3 107 ? 131.707 84.756  144.014 1.00 128.11 ? 107 LYS B CB  1 
ATOM 7092 C CG  . LYS C 3 107 ? 131.782 85.447  145.356 1.00 130.04 ? 107 LYS B CG  1 
ATOM 7093 C CD  . LYS C 3 107 ? 131.794 86.957  145.197 1.00 129.67 ? 107 LYS B CD  1 
ATOM 7094 C CE  . LYS C 3 107 ? 133.212 87.498  145.143 1.00 133.13 ? 107 LYS B CE  1 
ATOM 7095 N NZ  . LYS C 3 107 ? 134.019 87.061  146.315 1.00 132.82 ? 107 LYS B NZ  1 
ATOM 7096 N N   . ASP C 3 108 ? 131.239 82.094  146.217 1.00 135.04 ? 108 ASP B N   1 
ATOM 7097 C CA  . ASP C 3 108 ? 131.681 81.315  147.370 1.00 132.40 ? 108 ASP B CA  1 
ATOM 7098 C C   . ASP C 3 108 ? 131.475 79.818  147.218 1.00 133.00 ? 108 ASP B C   1 
ATOM 7099 O O   . ASP C 3 108 ? 132.246 79.044  147.786 1.00 135.48 ? 108 ASP B O   1 
ATOM 7100 C CB  . ASP C 3 108 ? 130.955 81.757  148.649 1.00 133.64 ? 108 ASP B CB  1 
ATOM 7101 C CG  . ASP C 3 108 ? 130.992 83.251  148.867 1.00 135.88 ? 108 ASP B CG  1 
ATOM 7102 O OD1 . ASP C 3 108 ? 131.381 83.982  147.940 1.00 137.29 ? 108 ASP B OD1 1 
ATOM 7103 O OD2 . ASP C 3 108 ? 130.634 83.696  149.977 1.00 133.48 ? 108 ASP B OD2 1 
ATOM 7104 N N   . PHE C 3 109 ? 130.459 79.391  146.476 1.00 110.99 ? 109 PHE B N   1 
ATOM 7105 C CA  . PHE C 3 109 ? 130.077 77.988  146.403 1.00 106.40 ? 109 PHE B CA  1 
ATOM 7106 C C   . PHE C 3 109 ? 130.615 77.354  145.129 1.00 109.70 ? 109 PHE B C   1 
ATOM 7107 O O   . PHE C 3 109 ? 130.609 77.976  144.064 1.00 113.63 ? 109 PHE B O   1 
ATOM 7108 C CB  . PHE C 3 109 ? 128.556 77.840  146.454 1.00 103.88 ? 109 PHE B CB  1 
ATOM 7109 C CG  . PHE C 3 109 ? 128.094 76.498  146.934 1.00 100.27 ? 109 PHE B CG  1 
ATOM 7110 C CD1 . PHE C 3 109 ? 127.875 75.467  146.040 1.00 106.06 ? 109 PHE B CD1 1 
ATOM 7111 C CD2 . PHE C 3 109 ? 127.876 76.267  148.279 1.00 104.42 ? 109 PHE B CD2 1 
ATOM 7112 C CE1 . PHE C 3 109 ? 127.450 74.232  146.478 1.00 107.56 ? 109 PHE B CE1 1 
ATOM 7113 C CE2 . PHE C 3 109 ? 127.449 75.034  148.723 1.00 107.66 ? 109 PHE B CE2 1 
ATOM 7114 C CZ  . PHE C 3 109 ? 127.237 74.015  147.821 1.00 105.77 ? 109 PHE B CZ  1 
ATOM 7115 N N   . CYS C 3 110 ? 131.079 76.113  145.246 1.00 140.13 ? 110 CYS B N   1 
ATOM 7116 C CA  . CYS C 3 110 ? 131.610 75.353  144.124 1.00 142.67 ? 110 CYS B CA  1 
ATOM 7117 C C   . CYS C 3 110 ? 130.857 74.037  143.996 1.00 142.40 ? 110 CYS B C   1 
ATOM 7118 O O   . CYS C 3 110 ? 130.634 73.340  144.990 1.00 143.18 ? 110 CYS B O   1 
ATOM 7119 C CB  . CYS C 3 110 ? 133.108 75.088  144.300 1.00 146.27 ? 110 CYS B CB  1 
ATOM 7120 S SG  . CYS C 3 110 ? 133.796 73.890  143.140 1.00 157.97 ? 110 CYS B SG  1 
ATOM 7121 N N   . THR C 3 111 ? 130.467 73.699  142.767 1.00 138.64 ? 111 THR B N   1 
ATOM 7122 C CA  . THR C 3 111 ? 129.694 72.492  142.498 1.00 139.85 ? 111 THR B CA  1 
ATOM 7123 C C   . THR C 3 111 ? 130.556 71.306  142.088 1.00 143.63 ? 111 THR B C   1 
ATOM 7124 O O   . THR C 3 111 ? 130.338 70.193  142.576 1.00 142.67 ? 111 THR B O   1 
ATOM 7125 C CB  . THR C 3 111 ? 128.656 72.755  141.403 1.00 138.32 ? 111 THR B CB  1 
ATOM 7126 O OG1 . THR C 3 111 ? 129.264 72.584  140.117 1.00 145.38 ? 111 THR B OG1 1 
ATOM 7127 C CG2 . THR C 3 111 ? 128.112 74.165  141.515 1.00 135.20 ? 111 THR B CG2 1 
ATOM 7128 N N   . LYS C 3 112 ? 131.524 71.514  141.198 1.00 159.75 ? 112 LYS B N   1 
ATOM 7129 C CA  . LYS C 3 112 ? 132.390 70.452  140.706 1.00 156.26 ? 112 LYS B CA  1 
ATOM 7130 C C   . LYS C 3 112 ? 133.827 70.759  141.097 1.00 158.29 ? 112 LYS B C   1 
ATOM 7131 O O   . LYS C 3 112 ? 134.342 71.835  140.780 1.00 158.47 ? 112 LYS B O   1 
ATOM 7132 C CB  . LYS C 3 112 ? 132.274 70.313  139.185 1.00 155.25 ? 112 LYS B CB  1 
ATOM 7133 C CG  . LYS C 3 112 ? 132.799 69.003  138.604 1.00 157.13 ? 112 LYS B CG  1 
ATOM 7134 C CD  . LYS C 3 112 ? 132.765 67.859  139.608 1.00 157.64 ? 112 LYS B CD  1 
ATOM 7135 C CE  . LYS C 3 112 ? 132.761 66.512  138.898 1.00 157.51 ? 112 LYS B CE  1 
ATOM 7136 N NZ  . LYS C 3 112 ? 131.651 66.402  137.911 1.00 156.69 ? 112 LYS B NZ  1 
ATOM 7137 N N   . CYS C 3 113 ? 134.467 69.818  141.779 1.00 182.58 ? 113 CYS B N   1 
ATOM 7138 C CA  . CYS C 3 113 ? 135.851 69.962  142.201 1.00 182.85 ? 113 CYS B CA  1 
ATOM 7139 C C   . CYS C 3 113 ? 136.771 69.299  141.185 1.00 182.92 ? 113 CYS B C   1 
ATOM 7140 O O   . CYS C 3 113 ? 136.429 68.281  140.577 1.00 183.73 ? 113 CYS B O   1 
ATOM 7141 C CB  . CYS C 3 113 ? 136.066 69.347  143.585 1.00 182.95 ? 113 CYS B CB  1 
ATOM 7142 S SG  . CYS C 3 113 ? 137.248 70.239  144.623 1.00 189.29 ? 113 CYS B SG  1 
ATOM 7143 N N   . LYS C 3 114 ? 137.931 69.935  140.986 1.00 186.52 ? 114 LYS B N   1 
ATOM 7144 C CA  . LYS C 3 114 ? 138.923 69.415  140.011 1.00 187.82 ? 114 LYS B CA  1 
ATOM 7145 C C   . LYS C 3 114 ? 139.351 68.010  140.429 1.00 189.82 ? 114 LYS B C   1 
ATOM 7146 O O   . LYS C 3 114 ? 139.419 67.743  141.646 1.00 191.30 ? 114 LYS B O   1 
ATOM 7147 C CB  . LYS C 3 114 ? 140.142 70.338  139.955 1.00 186.70 ? 114 LYS B CB  1 
ATOM 7148 C CG  . LYS C 3 114 ? 140.739 70.540  138.570 1.00 187.63 ? 114 LYS B CG  1 
ATOM 7149 C CD  . LYS C 3 114 ? 140.282 71.822  137.913 1.00 187.13 ? 114 LYS B CD  1 
ATOM 7150 C CE  . LYS C 3 114 ? 139.512 72.724  138.853 1.00 187.50 ? 114 LYS B CE  1 
ATOM 7151 N NZ  . LYS C 3 114 ? 140.153 74.052  138.988 1.00 188.03 ? 114 LYS B NZ  1 
ATOM 7152 N N   . VAL C 3 115 ? 139.640 67.158  139.448 1.00 193.66 ? 115 VAL B N   1 
ATOM 7153 C CA  . VAL C 3 115 ? 140.020 65.784  139.753 1.00 193.32 ? 115 VAL B CA  1 
ATOM 7154 C C   . VAL C 3 115 ? 141.310 65.772  140.561 1.00 193.01 ? 115 VAL B C   1 
ATOM 7155 O O   . VAL C 3 115 ? 142.252 66.524  140.285 1.00 191.51 ? 115 VAL B O   1 
ATOM 7156 C CB  . VAL C 3 115 ? 140.158 64.960  138.461 1.00 192.21 ? 115 VAL B CB  1 
ATOM 7157 C CG1 . VAL C 3 115 ? 141.070 65.659  137.470 1.00 191.13 ? 115 VAL B CG1 1 
ATOM 7158 C CG2 . VAL C 3 115 ? 140.679 63.560  138.775 1.00 192.68 ? 115 VAL B CG2 1 
ATOM 7159 N N   . GLY C 3 116 ? 141.346 64.926  141.587 1.00 194.55 ? 116 GLY B N   1 
ATOM 7160 C CA  . GLY C 3 116 ? 142.464 64.857  142.501 1.00 193.83 ? 116 GLY B CA  1 
ATOM 7161 C C   . GLY C 3 116 ? 142.262 65.580  143.813 1.00 193.50 ? 116 GLY B C   1 
ATOM 7162 O O   . GLY C 3 116 ? 143.156 65.539  144.667 1.00 193.86 ? 116 GLY B O   1 
ATOM 7163 N N   . PHE C 3 117 ? 141.118 66.234  144.005 1.00 189.81 ? 117 PHE B N   1 
ATOM 7164 C CA  . PHE C 3 117 ? 140.824 66.957  145.232 1.00 188.47 ? 117 PHE B CA  1 
ATOM 7165 C C   . PHE C 3 117 ? 139.378 66.708  145.636 1.00 189.35 ? 117 PHE B C   1 
ATOM 7166 O O   . PHE C 3 117 ? 138.534 66.337  144.818 1.00 191.70 ? 117 PHE B O   1 
ATOM 7167 C CB  . PHE C 3 117 ? 141.101 68.461  145.087 1.00 187.84 ? 117 PHE B CB  1 
ATOM 7168 C CG  . PHE C 3 117 ? 142.243 68.784  144.163 1.00 188.84 ? 117 PHE B CG  1 
ATOM 7169 C CD1 . PHE C 3 117 ? 142.047 68.892  142.797 1.00 189.02 ? 117 PHE B CD1 1 
ATOM 7170 C CD2 . PHE C 3 117 ? 143.517 68.979  144.668 1.00 189.81 ? 117 PHE B CD2 1 
ATOM 7171 C CE1 . PHE C 3 117 ? 143.100 69.182  141.950 1.00 189.62 ? 117 PHE B CE1 1 
ATOM 7172 C CE2 . PHE C 3 117 ? 144.575 69.273  143.828 1.00 190.71 ? 117 PHE B CE2 1 
ATOM 7173 C CZ  . PHE C 3 117 ? 144.364 69.376  142.467 1.00 190.77 ? 117 PHE B CZ  1 
ATOM 7174 N N   . TYR C 3 118 ? 139.107 66.930  146.917 1.00 192.45 ? 118 TYR B N   1 
ATOM 7175 C CA  . TYR C 3 118 ? 137.837 66.605  147.544 1.00 193.29 ? 118 TYR B CA  1 
ATOM 7176 C C   . TYR C 3 118 ? 136.832 67.750  147.622 1.00 193.80 ? 118 TYR B C   1 
ATOM 7177 O O   . TYR C 3 118 ? 137.197 68.921  147.768 1.00 195.19 ? 118 TYR B O   1 
ATOM 7178 C CB  . TYR C 3 118 ? 138.077 66.001  148.928 1.00 192.43 ? 118 TYR B CB  1 
ATOM 7179 C CG  . TYR C 3 118 ? 138.213 64.496  148.912 1.00 193.43 ? 118 TYR B CG  1 
ATOM 7180 C CD1 . TYR C 3 118 ? 138.219 63.765  150.091 1.00 193.63 ? 118 TYR B CD1 1 
ATOM 7181 C CD2 . TYR C 3 118 ? 138.334 63.807  147.715 1.00 193.62 ? 118 TYR B CD2 1 
ATOM 7182 C CE1 . TYR C 3 118 ? 138.353 62.391  150.074 1.00 193.34 ? 118 TYR B CE1 1 
ATOM 7183 C CE2 . TYR C 3 118 ? 138.461 62.433  147.690 1.00 193.80 ? 118 TYR B CE2 1 
ATOM 7184 C CZ  . TYR C 3 118 ? 138.469 61.729  148.872 1.00 194.11 ? 118 TYR B CZ  1 
ATOM 7185 O OH  . TYR C 3 118 ? 138.595 60.360  148.851 1.00 194.97 ? 118 TYR B OH  1 
ATOM 7186 N N   . LEU C 3 119 ? 135.537 67.391  147.450 1.00 172.25 ? 119 LEU B N   1 
ATOM 7187 C CA  . LEU C 3 119 ? 134.398 68.342  147.578 1.00 171.53 ? 119 LEU B CA  1 
ATOM 7188 C C   . LEU C 3 119 ? 133.507 68.179  148.795 1.00 171.27 ? 119 LEU B C   1 
ATOM 7189 O O   . LEU C 3 119 ? 133.068 67.047  149.020 1.00 170.89 ? 119 LEU B O   1 
ATOM 7190 C CB  . LEU C 3 119 ? 133.447 68.164  146.399 1.00 169.97 ? 119 LEU B CB  1 
ATOM 7191 C CG  . LEU C 3 119 ? 132.230 69.094  146.395 1.00 168.09 ? 119 LEU B CG  1 
ATOM 7192 C CD1 . LEU C 3 119 ? 132.633 70.553  146.285 1.00 168.15 ? 119 LEU B CD1 1 
ATOM 7193 C CD2 . LEU C 3 119 ? 131.251 68.727  145.294 1.00 167.58 ? 119 LEU B CD2 1 
ATOM 7194 N N   . HIS C 3 120 ? 133.241 69.246  149.537 1.00 162.71 ? 120 HIS B N   1 
ATOM 7195 C CA  . HIS C 3 120 ? 132.408 69.191  150.732 1.00 162.57 ? 120 HIS B CA  1 
ATOM 7196 C C   . HIS C 3 120 ? 131.840 70.546  151.123 1.00 161.46 ? 120 HIS B C   1 
ATOM 7197 O O   . HIS C 3 120 ? 132.601 71.475  151.409 1.00 162.19 ? 120 HIS B O   1 
ATOM 7198 C CB  . HIS C 3 120 ? 133.116 68.544  151.927 1.00 161.12 ? 120 HIS B CB  1 
ATOM 7199 C CG  . HIS C 3 120 ? 132.596 68.996  153.256 1.00 159.93 ? 120 HIS B CG  1 
ATOM 7200 N ND1 . HIS C 3 120 ? 131.533 68.386  153.886 1.00 161.36 ? 120 HIS B ND1 1 
ATOM 7201 C CD2 . HIS C 3 120 ? 132.996 69.996  154.077 1.00 160.01 ? 120 HIS B CD2 1 
ATOM 7202 C CE1 . HIS C 3 120 ? 131.299 68.992  155.036 1.00 162.16 ? 120 HIS B CE1 1 
ATOM 7203 N NE2 . HIS C 3 120 ? 132.172 69.972  155.176 1.00 162.07 ? 120 HIS B NE2 1 
ATOM 7204 N N   . ARG C 3 121 ? 130.509 70.644  151.150 1.00 139.13 ? 121 ARG B N   1 
ATOM 7205 C CA  . ARG C 3 121 ? 129.806 71.861  151.562 1.00 138.47 ? 121 ARG B CA  1 
ATOM 7206 C C   . ARG C 3 121 ? 130.238 73.066  150.728 1.00 138.80 ? 121 ARG B C   1 
ATOM 7207 O O   . ARG C 3 121 ? 130.441 74.165  151.246 1.00 137.67 ? 121 ARG B O   1 
ATOM 7208 C CB  . ARG C 3 121 ? 130.012 72.132  153.054 1.00 141.30 ? 121 ARG B CB  1 
ATOM 7209 C CG  . ARG C 3 121 ? 128.913 72.951  153.706 1.00 142.24 ? 121 ARG B CG  1 
ATOM 7210 C CD  . ARG C 3 121 ? 128.738 72.572  155.166 1.00 143.37 ? 121 ARG B CD  1 
ATOM 7211 N NE  . ARG C 3 121 ? 128.574 71.134  155.338 1.00 142.27 ? 121 ARG B NE  1 
ATOM 7212 C CZ  . ARG C 3 121 ? 127.407 70.506  155.322 1.00 141.62 ? 121 ARG B CZ  1 
ATOM 7213 N NH1 . ARG C 3 121 ? 126.271 71.161  155.148 1.00 141.02 ? 121 ARG B NH1 1 
ATOM 7214 N NH2 . ARG C 3 121 ? 127.379 69.186  155.483 1.00 139.64 ? 121 ARG B NH2 1 
ATOM 7215 N N   . GLY C 3 122 ? 130.393 72.857  149.423 1.00 136.22 ? 122 GLY B N   1 
ATOM 7216 C CA  . GLY C 3 122 ? 130.829 73.915  148.539 1.00 136.16 ? 122 GLY B CA  1 
ATOM 7217 C C   . GLY C 3 122 ? 132.281 74.310  148.684 1.00 136.69 ? 122 GLY B C   1 
ATOM 7218 O O   . GLY C 3 122 ? 132.715 75.262  148.022 1.00 131.98 ? 122 GLY B O   1 
ATOM 7219 N N   . ARG C 3 123 ? 133.043 73.612  149.518 1.00 160.59 ? 123 ARG B N   1 
ATOM 7220 C CA  . ARG C 3 123 ? 134.446 73.907  149.766 1.00 160.53 ? 123 ARG B CA  1 
ATOM 7221 C C   . ARG C 3 123 ? 135.287 72.860  149.052 1.00 158.19 ? 123 ARG B C   1 
ATOM 7222 O O   . ARG C 3 123 ? 134.996 71.664  149.140 1.00 156.59 ? 123 ARG B O   1 
ATOM 7223 C CB  . ARG C 3 123 ? 134.751 73.879  151.266 1.00 159.88 ? 123 ARG B CB  1 
ATOM 7224 C CG  . ARG C 3 123 ? 134.085 74.951  152.148 1.00 157.33 ? 123 ARG B CG  1 
ATOM 7225 C CD  . ARG C 3 123 ? 133.763 76.312  151.515 1.00 157.24 ? 123 ARG B CD  1 
ATOM 7226 N NE  . ARG C 3 123 ? 134.773 76.841  150.607 1.00 159.30 ? 123 ARG B NE  1 
ATOM 7227 C CZ  . ARG C 3 123 ? 134.761 78.080  150.134 1.00 159.06 ? 123 ARG B CZ  1 
ATOM 7228 N NH1 . ARG C 3 123 ? 133.794 78.928  150.442 1.00 158.55 ? 123 ARG B NH1 1 
ATOM 7229 N NH2 . ARG C 3 123 ? 135.749 78.483  149.341 1.00 158.00 ? 123 ARG B NH2 1 
ATOM 7230 N N   . CYS C 3 124 ? 136.325 73.302  148.352 1.00 174.42 ? 124 CYS B N   1 
ATOM 7231 C CA  . CYS C 3 124 ? 137.248 72.400  147.679 1.00 174.99 ? 124 CYS B CA  1 
ATOM 7232 C C   . CYS C 3 124 ? 138.580 72.403  148.413 1.00 177.42 ? 124 CYS B C   1 
ATOM 7233 O O   . CYS C 3 124 ? 139.182 73.464  148.609 1.00 178.31 ? 124 CYS B O   1 
ATOM 7234 C CB  . CYS C 3 124 ? 137.445 72.802  146.216 1.00 175.90 ? 124 CYS B CB  1 
ATOM 7235 S SG  . CYS C 3 124 ? 136.312 71.979  145.078 1.00 185.09 ? 124 CYS B SG  1 
ATOM 7236 N N   . PHE C 3 125 ? 139.033 71.222  148.814 1.00 185.27 ? 125 PHE B N   1 
ATOM 7237 C CA  . PHE C 3 125 ? 140.309 71.080  149.509 1.00 184.49 ? 125 PHE B CA  1 
ATOM 7238 C C   . PHE C 3 125 ? 140.891 69.719  149.139 1.00 184.46 ? 125 PHE B C   1 
ATOM 7239 O O   . PHE C 3 125 ? 140.471 69.103  148.156 1.00 184.55 ? 125 PHE B O   1 
ATOM 7240 C CB  . PHE C 3 125 ? 140.131 71.284  151.025 1.00 184.14 ? 125 PHE B CB  1 
ATOM 7241 C CG  . PHE C 3 125 ? 138.802 70.824  151.557 1.00 183.97 ? 125 PHE B CG  1 
ATOM 7242 C CD1 . PHE C 3 125 ? 138.397 69.508  151.417 1.00 184.47 ? 125 PHE B CD1 1 
ATOM 7243 C CD2 . PHE C 3 125 ? 137.964 71.711  152.214 1.00 182.86 ? 125 PHE B CD2 1 
ATOM 7244 C CE1 . PHE C 3 125 ? 137.177 69.086  151.913 1.00 184.79 ? 125 PHE B CE1 1 
ATOM 7245 C CE2 . PHE C 3 125 ? 136.743 71.295  152.713 1.00 182.47 ? 125 PHE B CE2 1 
ATOM 7246 C CZ  . PHE C 3 125 ? 136.349 69.981  152.562 1.00 183.82 ? 125 PHE B CZ  1 
ATOM 7247 N N   . ASP C 3 126 ? 141.877 69.255  149.905 1.00 192.02 ? 126 ASP B N   1 
ATOM 7248 C CA  . ASP C 3 126 ? 142.542 67.990  149.614 1.00 193.02 ? 126 ASP B CA  1 
ATOM 7249 C C   . ASP C 3 126 ? 142.302 66.909  150.655 1.00 191.72 ? 126 ASP B C   1 
ATOM 7250 O O   . ASP C 3 126 ? 142.378 65.724  150.323 1.00 190.23 ? 126 ASP B O   1 
ATOM 7251 C CB  . ASP C 3 126 ? 144.054 68.203  149.468 1.00 192.70 ? 126 ASP B CB  1 
ATOM 7252 C CG  . ASP C 3 126 ? 144.415 69.026  148.244 1.00 192.84 ? 126 ASP B CG  1 
ATOM 7253 O OD1 . ASP C 3 126 ? 145.590 68.988  147.824 1.00 192.64 ? 126 ASP B OD1 1 
ATOM 7254 O OD2 . ASP C 3 126 ? 143.523 69.711  147.700 1.00 192.45 ? 126 ASP B OD2 1 
ATOM 7255 N N   . GLU C 3 127 ? 142.017 67.282  151.899 1.00 208.84 ? 127 GLU B N   1 
ATOM 7256 C CA  . GLU C 3 127 ? 141.880 66.337  152.999 1.00 210.11 ? 127 GLU B CA  1 
ATOM 7257 C C   . GLU C 3 127 ? 140.476 66.478  153.571 1.00 210.87 ? 127 GLU B C   1 
ATOM 7258 O O   . GLU C 3 127 ? 140.033 67.591  153.877 1.00 211.28 ? 127 GLU B O   1 
ATOM 7259 C CB  . GLU C 3 127 ? 143.021 66.575  154.021 1.00 210.05 ? 127 GLU B CB  1 
ATOM 7260 C CG  . GLU C 3 127 ? 143.150 65.706  155.306 1.00 211.36 ? 127 GLU B CG  1 
ATOM 7261 C CD  . GLU C 3 127 ? 141.946 65.649  156.232 1.00 212.12 ? 127 GLU B CD  1 
ATOM 7262 O OE1 . GLU C 3 127 ? 141.089 66.548  156.187 1.00 212.14 ? 127 GLU B OE1 1 
ATOM 7263 O OE2 . GLU C 3 127 ? 141.857 64.679  157.012 1.00 211.86 ? 127 GLU B OE2 1 
ATOM 7264 N N   . CYS C 3 128 ? 139.776 65.353  153.692 1.00 213.45 ? 128 CYS B N   1 
ATOM 7265 C CA  . CYS C 3 128 ? 138.379 65.372  154.119 1.00 213.73 ? 128 CYS B CA  1 
ATOM 7266 C C   . CYS C 3 128 ? 138.284 65.702  155.604 1.00 213.93 ? 128 CYS B C   1 
ATOM 7267 O O   . CYS C 3 128 ? 138.919 65.028  156.424 1.00 214.20 ? 128 CYS B O   1 
ATOM 7268 C CB  . CYS C 3 128 ? 137.717 64.026  153.836 1.00 214.13 ? 128 CYS B CB  1 
ATOM 7269 S SG  . CYS C 3 128 ? 135.923 64.011  154.074 1.00 221.57 ? 128 CYS B SG  1 
ATOM 7270 N N   . PRO C 3 129 ? 137.490 66.699  155.990 1.00 207.53 ? 129 PRO B N   1 
ATOM 7271 C CA  . PRO C 3 129 ? 137.441 67.108  157.399 1.00 206.59 ? 129 PRO B CA  1 
ATOM 7272 C C   . PRO C 3 129 ? 136.920 65.997  158.297 1.00 207.12 ? 129 PRO B C   1 
ATOM 7273 O O   . PRO C 3 129 ? 136.192 65.097  157.871 1.00 206.40 ? 129 PRO B O   1 
ATOM 7274 C CB  . PRO C 3 129 ? 136.488 68.311  157.393 1.00 205.33 ? 129 PRO B CB  1 
ATOM 7275 C CG  . PRO C 3 129 ? 136.408 68.749  155.966 1.00 205.97 ? 129 PRO B CG  1 
ATOM 7276 C CD  . PRO C 3 129 ? 136.615 67.522  155.140 1.00 207.53 ? 129 PRO B CD  1 
ATOM 7277 N N   . ASP C 3 130 ? 137.318 66.071  159.566 1.00 205.71 ? 130 ASP B N   1 
ATOM 7278 C CA  . ASP C 3 130 ? 136.965 65.041  160.532 1.00 205.75 ? 130 ASP B CA  1 
ATOM 7279 C C   . ASP C 3 130 ? 135.458 65.004  160.761 1.00 206.10 ? 130 ASP B C   1 
ATOM 7280 O O   . ASP C 3 130 ? 134.750 65.997  160.575 1.00 205.44 ? 130 ASP B O   1 
ATOM 7281 C CB  . ASP C 3 130 ? 137.690 65.283  161.856 1.00 204.57 ? 130 ASP B CB  1 
ATOM 7282 N N   . GLY C 3 131 ? 134.971 63.837  161.177 1.00 203.85 ? 131 GLY B N   1 
ATOM 7283 C CA  . GLY C 3 131 ? 133.554 63.615  161.355 1.00 203.23 ? 131 GLY B CA  1 
ATOM 7284 C C   . GLY C 3 131 ? 132.812 63.193  160.107 1.00 203.05 ? 131 GLY B C   1 
ATOM 7285 O O   . GLY C 3 131 ? 131.584 63.044  160.156 1.00 201.63 ? 131 GLY B O   1 
ATOM 7286 N N   . PHE C 3 132 ? 133.512 62.994  158.993 1.00 198.40 ? 132 PHE B N   1 
ATOM 7287 C CA  . PHE C 3 132 ? 132.895 62.598  157.738 1.00 197.91 ? 132 PHE B CA  1 
ATOM 7288 C C   . PHE C 3 132 ? 133.653 61.419  157.147 1.00 197.86 ? 132 PHE B C   1 
ATOM 7289 O O   . PHE C 3 132 ? 134.864 61.278  157.339 1.00 195.93 ? 132 PHE B O   1 
ATOM 7290 C CB  . PHE C 3 132 ? 132.869 63.759  156.736 1.00 197.15 ? 132 PHE B CB  1 
ATOM 7291 C CG  . PHE C 3 132 ? 131.674 64.654  156.880 1.00 197.40 ? 132 PHE B CG  1 
ATOM 7292 C CD1 . PHE C 3 132 ? 130.410 64.204  156.536 1.00 196.87 ? 132 PHE B CD1 1 
ATOM 7293 C CD2 . PHE C 3 132 ? 131.812 65.943  157.367 1.00 196.08 ? 132 PHE B CD2 1 
ATOM 7294 C CE1 . PHE C 3 132 ? 129.308 65.025  156.671 1.00 197.17 ? 132 PHE B CE1 1 
ATOM 7295 C CE2 . PHE C 3 132 ? 130.714 66.768  157.504 1.00 196.34 ? 132 PHE B CE2 1 
ATOM 7296 C CZ  . PHE C 3 132 ? 129.460 66.309  157.155 1.00 197.35 ? 132 PHE B CZ  1 
ATOM 7297 N N   . ALA C 3 133 ? 132.925 60.571  156.421 1.00 211.39 ? 133 ALA B N   1 
ATOM 7298 C CA  . ALA C 3 133 ? 133.510 59.395  155.784 1.00 211.15 ? 133 ALA B CA  1 
ATOM 7299 C C   . ALA C 3 133 ? 133.570 59.614  154.279 1.00 212.15 ? 133 ALA B C   1 
ATOM 7300 O O   . ALA C 3 133 ? 132.550 59.464  153.588 1.00 211.07 ? 133 ALA B O   1 
ATOM 7301 C CB  . ALA C 3 133 ? 132.698 58.140  156.113 1.00 208.78 ? 133 ALA B CB  1 
ATOM 7302 N N   . PRO C 3 134 ? 134.724 59.967  153.725 1.00 211.19 ? 134 PRO B N   1 
ATOM 7303 C CA  . PRO C 3 134 ? 134.812 60.228  152.287 1.00 209.73 ? 134 PRO B CA  1 
ATOM 7304 C C   . PRO C 3 134 ? 134.822 58.947  151.467 1.00 209.15 ? 134 PRO B C   1 
ATOM 7305 O O   . PRO C 3 134 ? 135.156 57.863  151.949 1.00 209.00 ? 134 PRO B O   1 
ATOM 7306 C CB  . PRO C 3 134 ? 136.142 60.973  152.152 1.00 207.84 ? 134 PRO B CB  1 
ATOM 7307 C CG  . PRO C 3 134 ? 136.964 60.453  153.278 1.00 207.52 ? 134 PRO B CG  1 
ATOM 7308 C CD  . PRO C 3 134 ? 136.005 60.209  154.412 1.00 209.05 ? 134 PRO B CD  1 
ATOM 7309 N N   . LEU C 3 135 ? 134.444 59.096  150.199 1.00 211.04 ? 135 LEU B N   1 
ATOM 7310 C CA  . LEU C 3 135 ? 134.478 58.000  149.241 1.00 210.96 ? 135 LEU B CA  1 
ATOM 7311 C C   . LEU C 3 135 ? 135.077 58.520  147.942 1.00 211.28 ? 135 LEU B C   1 
ATOM 7312 O O   . LEU C 3 135 ? 134.726 59.612  147.485 1.00 211.86 ? 135 LEU B O   1 
ATOM 7313 C CB  . LEU C 3 135 ? 133.073 57.410  149.033 1.00 210.88 ? 135 LEU B CB  1 
ATOM 7314 C CG  . LEU C 3 135 ? 132.041 57.979  148.053 1.00 210.56 ? 135 LEU B CG  1 
ATOM 7315 C CD1 . LEU C 3 135 ? 132.265 57.465  146.640 1.00 210.23 ? 135 LEU B CD1 1 
ATOM 7316 C CD2 . LEU C 3 135 ? 130.627 57.669  148.521 1.00 209.97 ? 135 LEU B CD2 1 
ATOM 7317 N N   . ASP C 3 136 ? 135.992 57.742  147.361 1.00 221.61 ? 136 ASP B N   1 
ATOM 7318 C CA  . ASP C 3 136 ? 136.793 58.227  146.241 1.00 222.15 ? 136 ASP B CA  1 
ATOM 7319 C C   . ASP C 3 136 ? 136.034 58.232  144.919 1.00 222.17 ? 136 ASP B C   1 
ATOM 7320 O O   . ASP C 3 136 ? 136.361 59.030  144.032 1.00 222.27 ? 136 ASP B O   1 
ATOM 7321 C CB  . ASP C 3 136 ? 138.063 57.384  146.104 1.00 222.56 ? 136 ASP B CB  1 
ATOM 7322 C CG  . ASP C 3 136 ? 139.077 57.679  147.192 1.00 223.35 ? 136 ASP B CG  1 
ATOM 7323 O OD1 . ASP C 3 136 ? 139.583 58.821  147.241 1.00 223.33 ? 136 ASP B OD1 1 
ATOM 7324 O OD2 . ASP C 3 136 ? 139.368 56.771  147.998 1.00 223.70 ? 136 ASP B OD2 1 
ATOM 7325 N N   . GLU C 3 137 ? 135.039 57.355  144.758 1.00 219.94 ? 137 GLU B N   1 
ATOM 7326 C CA  . GLU C 3 137 ? 134.381 57.214  143.460 1.00 219.86 ? 137 GLU B CA  1 
ATOM 7327 C C   . GLU C 3 137 ? 133.680 58.501  143.042 1.00 220.50 ? 137 GLU B C   1 
ATOM 7328 O O   . GLU C 3 137 ? 133.794 58.932  141.889 1.00 219.69 ? 137 GLU B O   1 
ATOM 7329 C CB  . GLU C 3 137 ? 133.389 56.051  143.499 1.00 218.68 ? 137 GLU B CB  1 
ATOM 7330 N N   . THR C 3 138 ? 132.990 59.136  143.995 1.00 217.44 ? 138 THR B N   1 
ATOM 7331 C CA  . THR C 3 138 ? 132.261 60.402  143.712 1.00 216.67 ? 138 THR B CA  1 
ATOM 7332 C C   . THR C 3 138 ? 133.194 61.594  143.930 1.00 216.09 ? 138 THR B C   1 
ATOM 7333 O O   . THR C 3 138 ? 132.824 62.706  143.506 1.00 215.63 ? 138 THR B O   1 
ATOM 7334 C CB  . THR C 3 138 ? 131.033 60.527  144.617 1.00 217.07 ? 138 THR B CB  1 
ATOM 7335 O OG1 . THR C 3 138 ? 131.511 60.460  145.959 1.00 217.26 ? 138 THR B OG1 1 
ATOM 7336 C CG2 . THR C 3 138 ? 130.012 59.438  144.379 1.00 215.56 ? 138 THR B CG2 1 
ATOM 7337 N N   . MET C 3 139 ? 134.331 61.376  144.595 1.00 207.79 ? 139 MET B N   1 
ATOM 7338 C CA  . MET C 3 139 ? 135.322 62.430  144.818 1.00 206.83 ? 139 MET B CA  1 
ATOM 7339 C C   . MET C 3 139 ? 134.790 63.519  145.750 1.00 206.39 ? 139 MET B C   1 
ATOM 7340 O O   . MET C 3 139 ? 135.040 64.708  145.547 1.00 205.43 ? 139 MET B O   1 
ATOM 7341 C CB  . MET C 3 139 ? 135.777 63.033  143.485 1.00 206.38 ? 139 MET B CB  1 
ATOM 7342 C CG  . MET C 3 139 ? 137.216 63.531  143.446 1.00 206.56 ? 139 MET B CG  1 
ATOM 7343 S SD  . MET C 3 139 ? 138.411 62.261  143.909 1.00 206.94 ? 139 MET B SD  1 
ATOM 7344 C CE  . MET C 3 139 ? 139.744 63.262  144.561 1.00 205.61 ? 139 MET B CE  1 
ATOM 7345 N N   . GLU C 3 140 ? 134.043 63.083  146.763 1.00 211.77 ? 140 GLU B N   1 
ATOM 7346 C CA  . GLU C 3 140 ? 133.467 64.056  147.721 1.00 211.89 ? 140 GLU B CA  1 
ATOM 7347 C C   . GLU C 3 140 ? 133.363 63.408  149.101 1.00 212.59 ? 140 GLU B C   1 
ATOM 7348 O O   . GLU C 3 140 ? 133.349 62.163  149.176 1.00 213.45 ? 140 GLU B O   1 
ATOM 7349 C CB  . GLU C 3 140 ? 132.094 64.524  147.236 1.00 211.87 ? 140 GLU B CB  1 
ATOM 7350 C CG  . GLU C 3 140 ? 131.157 63.383  146.889 1.00 212.17 ? 140 GLU B CG  1 
ATOM 7351 C CD  . GLU C 3 140 ? 130.584 62.652  148.091 1.00 213.15 ? 140 GLU B CD  1 
ATOM 7352 O OE1 . GLU C 3 140 ? 130.101 63.331  149.017 1.00 214.26 ? 140 GLU B OE1 1 
ATOM 7353 O OE2 . GLU C 3 140 ? 130.635 61.406  148.105 1.00 213.29 ? 140 GLU B OE2 1 
ATOM 7354 N N   . CYS C 3 141 ? 133.307 64.230  150.144 1.00 210.60 ? 141 CYS B N   1 
ATOM 7355 C CA  . CYS C 3 141 ? 133.150 63.732  151.507 1.00 210.63 ? 141 CYS B CA  1 
ATOM 7356 C C   . CYS C 3 141 ? 131.747 63.187  151.746 1.00 209.43 ? 141 CYS B C   1 
ATOM 7357 O O   . CYS C 3 141 ? 131.561 61.986  151.939 1.00 208.93 ? 141 CYS B O   1 
ATOM 7358 C CB  . CYS C 3 141 ? 133.460 64.836  152.519 1.00 210.69 ? 141 CYS B CB  1 
ATOM 7359 S SG  . CYS C 3 141 ? 135.211 65.261  152.639 1.00 220.13 ? 141 CYS B SG  1 
# 
