data_8XU1
# 
_entry.id   8XU1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8XU1         pdb_00008xu1 10.2210/pdb8xu1/pdb 
WWPDB D_1300044050 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8XU1 
_pdbx_database_status.recvd_initial_deposition_date   2024-01-12 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              yl521gl@ustc.edu.cn 
_pdbx_contact_author.name_first         Lin 
_pdbx_contact_author.name_last          Yang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-1550-6947 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yang, L.'   1 0000-0003-1550-6947 
'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'DaCS-oxaloacetate complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yang, L.'   1 0000-0003-1550-6947 
primary 'Fang, Y.J.' 2 0009-0009-0272-0830 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'citrate synthase' 48927.250 3   2.3.3.16 ? ? ? 
2 non-polymer syn 'OXALOACETATE ION' 131.064   3   ?        ? ? ? 
3 water       nat water              18.015    119 ?        ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSFLKEKLAEKIAQHRPRTTRLLKEFGNVKIDEVTISQAIGGMRGIKSLVTDISYLDPEEGIRFRGYTIPEVLEKLPKVP
GAEMPYVEGHFYLLLTGDVPTEKEVKEVAEEFKKRRALPEYVKDTLKAMPRDTHPMTMFAAGILAMQRESKFAAYYNAGK
FNKNTAWEPMFEDAMDLMAKLPSLGAYIYRMKYKSDTHIPSNPDLDLGGDFANMMGIDKPYDDVARLYFILHSDHESGNV
SAHTAHLVASALSDAYYAYSAAMCGLAGPLHGLANQEVLKWIQETIDKKLGGKVPTKEELKKFVEETLSSGQVIPGYGHA
VLRKTDPRYVAQREFALKHMPDDPIFQVVSMLYEVVPPILSSLGKVKDPWPNVDAHSGCIQWHYGVVEYDFYTVLFGIGR
ALGVLANLVWDRALGYAIERPKSVTTDMLEKWAGI
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSFLKEKLAEKIAQHRPRTTRLLKEFGNVKIDEVTISQAIGGMRGIKSLVTDISYLDPEEGIRFRGYTIPEVLEKLPKVP
GAEMPYVEGHFYLLLTGDVPTEKEVKEVAEEFKKRRALPEYVKDTLKAMPRDTHPMTMFAAGILAMQRESKFAAYYNAGK
FNKNTAWEPMFEDAMDLMAKLPSLGAYIYRMKYKSDTHIPSNPDLDLGGDFANMMGIDKPYDDVARLYFILHSDHESGNV
SAHTAHLVASALSDAYYAYSAAMCGLAGPLHGLANQEVLKWIQETIDKKLGGKVPTKEELKKFVEETLSSGQVIPGYGHA
VLRKTDPRYVAQREFALKHMPDDPIFQVVSMLYEVVPPILSSLGKVKDPWPNVDAHSGCIQWHYGVVEYDFYTVLFGIGR
ALGVLANLVWDRALGYAIERPKSVTTDMLEKWAGI
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'OXALOACETATE ION' OAA 
3 water              HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   PHE n 
1 4   LEU n 
1 5   LYS n 
1 6   GLU n 
1 7   LYS n 
1 8   LEU n 
1 9   ALA n 
1 10  GLU n 
1 11  LYS n 
1 12  ILE n 
1 13  ALA n 
1 14  GLN n 
1 15  HIS n 
1 16  ARG n 
1 17  PRO n 
1 18  ARG n 
1 19  THR n 
1 20  THR n 
1 21  ARG n 
1 22  LEU n 
1 23  LEU n 
1 24  LYS n 
1 25  GLU n 
1 26  PHE n 
1 27  GLY n 
1 28  ASN n 
1 29  VAL n 
1 30  LYS n 
1 31  ILE n 
1 32  ASP n 
1 33  GLU n 
1 34  VAL n 
1 35  THR n 
1 36  ILE n 
1 37  SER n 
1 38  GLN n 
1 39  ALA n 
1 40  ILE n 
1 41  GLY n 
1 42  GLY n 
1 43  MET n 
1 44  ARG n 
1 45  GLY n 
1 46  ILE n 
1 47  LYS n 
1 48  SER n 
1 49  LEU n 
1 50  VAL n 
1 51  THR n 
1 52  ASP n 
1 53  ILE n 
1 54  SER n 
1 55  TYR n 
1 56  LEU n 
1 57  ASP n 
1 58  PRO n 
1 59  GLU n 
1 60  GLU n 
1 61  GLY n 
1 62  ILE n 
1 63  ARG n 
1 64  PHE n 
1 65  ARG n 
1 66  GLY n 
1 67  TYR n 
1 68  THR n 
1 69  ILE n 
1 70  PRO n 
1 71  GLU n 
1 72  VAL n 
1 73  LEU n 
1 74  GLU n 
1 75  LYS n 
1 76  LEU n 
1 77  PRO n 
1 78  LYS n 
1 79  VAL n 
1 80  PRO n 
1 81  GLY n 
1 82  ALA n 
1 83  GLU n 
1 84  MET n 
1 85  PRO n 
1 86  TYR n 
1 87  VAL n 
1 88  GLU n 
1 89  GLY n 
1 90  HIS n 
1 91  PHE n 
1 92  TYR n 
1 93  LEU n 
1 94  LEU n 
1 95  LEU n 
1 96  THR n 
1 97  GLY n 
1 98  ASP n 
1 99  VAL n 
1 100 PRO n 
1 101 THR n 
1 102 GLU n 
1 103 LYS n 
1 104 GLU n 
1 105 VAL n 
1 106 LYS n 
1 107 GLU n 
1 108 VAL n 
1 109 ALA n 
1 110 GLU n 
1 111 GLU n 
1 112 PHE n 
1 113 LYS n 
1 114 LYS n 
1 115 ARG n 
1 116 ARG n 
1 117 ALA n 
1 118 LEU n 
1 119 PRO n 
1 120 GLU n 
1 121 TYR n 
1 122 VAL n 
1 123 LYS n 
1 124 ASP n 
1 125 THR n 
1 126 LEU n 
1 127 LYS n 
1 128 ALA n 
1 129 MET n 
1 130 PRO n 
1 131 ARG n 
1 132 ASP n 
1 133 THR n 
1 134 HIS n 
1 135 PRO n 
1 136 MET n 
1 137 THR n 
1 138 MET n 
1 139 PHE n 
1 140 ALA n 
1 141 ALA n 
1 142 GLY n 
1 143 ILE n 
1 144 LEU n 
1 145 ALA n 
1 146 MET n 
1 147 GLN n 
1 148 ARG n 
1 149 GLU n 
1 150 SER n 
1 151 LYS n 
1 152 PHE n 
1 153 ALA n 
1 154 ALA n 
1 155 TYR n 
1 156 TYR n 
1 157 ASN n 
1 158 ALA n 
1 159 GLY n 
1 160 LYS n 
1 161 PHE n 
1 162 ASN n 
1 163 LYS n 
1 164 ASN n 
1 165 THR n 
1 166 ALA n 
1 167 TRP n 
1 168 GLU n 
1 169 PRO n 
1 170 MET n 
1 171 PHE n 
1 172 GLU n 
1 173 ASP n 
1 174 ALA n 
1 175 MET n 
1 176 ASP n 
1 177 LEU n 
1 178 MET n 
1 179 ALA n 
1 180 LYS n 
1 181 LEU n 
1 182 PRO n 
1 183 SER n 
1 184 LEU n 
1 185 GLY n 
1 186 ALA n 
1 187 TYR n 
1 188 ILE n 
1 189 TYR n 
1 190 ARG n 
1 191 MET n 
1 192 LYS n 
1 193 TYR n 
1 194 LYS n 
1 195 SER n 
1 196 ASP n 
1 197 THR n 
1 198 HIS n 
1 199 ILE n 
1 200 PRO n 
1 201 SER n 
1 202 ASN n 
1 203 PRO n 
1 204 ASP n 
1 205 LEU n 
1 206 ASP n 
1 207 LEU n 
1 208 GLY n 
1 209 GLY n 
1 210 ASP n 
1 211 PHE n 
1 212 ALA n 
1 213 ASN n 
1 214 MET n 
1 215 MET n 
1 216 GLY n 
1 217 ILE n 
1 218 ASP n 
1 219 LYS n 
1 220 PRO n 
1 221 TYR n 
1 222 ASP n 
1 223 ASP n 
1 224 VAL n 
1 225 ALA n 
1 226 ARG n 
1 227 LEU n 
1 228 TYR n 
1 229 PHE n 
1 230 ILE n 
1 231 LEU n 
1 232 HIS n 
1 233 SER n 
1 234 ASP n 
1 235 HIS n 
1 236 GLU n 
1 237 SER n 
1 238 GLY n 
1 239 ASN n 
1 240 VAL n 
1 241 SER n 
1 242 ALA n 
1 243 HIS n 
1 244 THR n 
1 245 ALA n 
1 246 HIS n 
1 247 LEU n 
1 248 VAL n 
1 249 ALA n 
1 250 SER n 
1 251 ALA n 
1 252 LEU n 
1 253 SER n 
1 254 ASP n 
1 255 ALA n 
1 256 TYR n 
1 257 TYR n 
1 258 ALA n 
1 259 TYR n 
1 260 SER n 
1 261 ALA n 
1 262 ALA n 
1 263 MET n 
1 264 CYS n 
1 265 GLY n 
1 266 LEU n 
1 267 ALA n 
1 268 GLY n 
1 269 PRO n 
1 270 LEU n 
1 271 HIS n 
1 272 GLY n 
1 273 LEU n 
1 274 ALA n 
1 275 ASN n 
1 276 GLN n 
1 277 GLU n 
1 278 VAL n 
1 279 LEU n 
1 280 LYS n 
1 281 TRP n 
1 282 ILE n 
1 283 GLN n 
1 284 GLU n 
1 285 THR n 
1 286 ILE n 
1 287 ASP n 
1 288 LYS n 
1 289 LYS n 
1 290 LEU n 
1 291 GLY n 
1 292 GLY n 
1 293 LYS n 
1 294 VAL n 
1 295 PRO n 
1 296 THR n 
1 297 LYS n 
1 298 GLU n 
1 299 GLU n 
1 300 LEU n 
1 301 LYS n 
1 302 LYS n 
1 303 PHE n 
1 304 VAL n 
1 305 GLU n 
1 306 GLU n 
1 307 THR n 
1 308 LEU n 
1 309 SER n 
1 310 SER n 
1 311 GLY n 
1 312 GLN n 
1 313 VAL n 
1 314 ILE n 
1 315 PRO n 
1 316 GLY n 
1 317 TYR n 
1 318 GLY n 
1 319 HIS n 
1 320 ALA n 
1 321 VAL n 
1 322 LEU n 
1 323 ARG n 
1 324 LYS n 
1 325 THR n 
1 326 ASP n 
1 327 PRO n 
1 328 ARG n 
1 329 TYR n 
1 330 VAL n 
1 331 ALA n 
1 332 GLN n 
1 333 ARG n 
1 334 GLU n 
1 335 PHE n 
1 336 ALA n 
1 337 LEU n 
1 338 LYS n 
1 339 HIS n 
1 340 MET n 
1 341 PRO n 
1 342 ASP n 
1 343 ASP n 
1 344 PRO n 
1 345 ILE n 
1 346 PHE n 
1 347 GLN n 
1 348 VAL n 
1 349 VAL n 
1 350 SER n 
1 351 MET n 
1 352 LEU n 
1 353 TYR n 
1 354 GLU n 
1 355 VAL n 
1 356 VAL n 
1 357 PRO n 
1 358 PRO n 
1 359 ILE n 
1 360 LEU n 
1 361 SER n 
1 362 SER n 
1 363 LEU n 
1 364 GLY n 
1 365 LYS n 
1 366 VAL n 
1 367 LYS n 
1 368 ASP n 
1 369 PRO n 
1 370 TRP n 
1 371 PRO n 
1 372 ASN n 
1 373 VAL n 
1 374 ASP n 
1 375 ALA n 
1 376 HIS n 
1 377 SER n 
1 378 GLY n 
1 379 CYS n 
1 380 ILE n 
1 381 GLN n 
1 382 TRP n 
1 383 HIS n 
1 384 TYR n 
1 385 GLY n 
1 386 VAL n 
1 387 VAL n 
1 388 GLU n 
1 389 TYR n 
1 390 ASP n 
1 391 PHE n 
1 392 TYR n 
1 393 THR n 
1 394 VAL n 
1 395 LEU n 
1 396 PHE n 
1 397 GLY n 
1 398 ILE n 
1 399 GLY n 
1 400 ARG n 
1 401 ALA n 
1 402 LEU n 
1 403 GLY n 
1 404 VAL n 
1 405 LEU n 
1 406 ALA n 
1 407 ASN n 
1 408 LEU n 
1 409 VAL n 
1 410 TRP n 
1 411 ASP n 
1 412 ARG n 
1 413 ALA n 
1 414 LEU n 
1 415 GLY n 
1 416 TYR n 
1 417 ALA n 
1 418 ILE n 
1 419 GLU n 
1 420 ARG n 
1 421 PRO n 
1 422 LYS n 
1 423 SER n 
1 424 VAL n 
1 425 THR n 
1 426 THR n 
1 427 ASP n 
1 428 MET n 
1 429 LEU n 
1 430 GLU n 
1 431 LYS n 
1 432 TRP n 
1 433 ALA n 
1 434 GLY n 
1 435 ILE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   435 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Desulfurella acetivorans A63' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     694431 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE            ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE           ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE         ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'    ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE           ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE          ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'    ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE            ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE          ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER              ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE         ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE            ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE             ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE         ? 'C5 H11 N O2 S'  149.211 
OAA non-polymer         . 'OXALOACETATE ION' ? 'C4 H3 O5 -1'    131.064 
PHE 'L-peptide linking' y PHENYLALANINE      ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE            ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE             ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE          ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN         ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE           ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE             ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   SER 2   2   2   SER SER A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   LEU 4   4   4   LEU LEU A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   GLU 6   6   6   GLU GLU A . n 
A 1 7   LYS 7   7   7   LYS LYS A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   ALA 9   9   9   ALA ALA A . n 
A 1 10  GLU 10  10  10  GLU GLU A . n 
A 1 11  LYS 11  11  11  LYS LYS A . n 
A 1 12  ILE 12  12  12  ILE ILE A . n 
A 1 13  ALA 13  13  13  ALA ALA A . n 
A 1 14  GLN 14  14  14  GLN GLN A . n 
A 1 15  HIS 15  15  15  HIS HIS A . n 
A 1 16  ARG 16  16  16  ARG ARG A . n 
A 1 17  PRO 17  17  17  PRO PRO A . n 
A 1 18  ARG 18  18  18  ARG ARG A . n 
A 1 19  THR 19  19  19  THR THR A . n 
A 1 20  THR 20  20  20  THR THR A . n 
A 1 21  ARG 21  21  21  ARG ARG A . n 
A 1 22  LEU 22  22  22  LEU LEU A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  GLU 25  25  25  GLU GLU A . n 
A 1 26  PHE 26  26  26  PHE PHE A . n 
A 1 27  GLY 27  27  27  GLY GLY A . n 
A 1 28  ASN 28  28  28  ASN ASN A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  LYS 30  30  30  LYS LYS A . n 
A 1 31  ILE 31  31  31  ILE ILE A . n 
A 1 32  ASP 32  32  32  ASP ASP A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  THR 35  35  35  THR THR A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  SER 37  37  37  SER SER A . n 
A 1 38  GLN 38  38  38  GLN GLN A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  ILE 40  40  40  ILE ILE A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  MET 43  43  43  MET MET A . n 
A 1 44  ARG 44  44  44  ARG ARG A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  ILE 46  46  46  ILE ILE A . n 
A 1 47  LYS 47  47  47  LYS LYS A . n 
A 1 48  SER 48  48  48  SER SER A . n 
A 1 49  LEU 49  49  49  LEU LEU A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  THR 51  51  51  THR THR A . n 
A 1 52  ASP 52  52  52  ASP ASP A . n 
A 1 53  ILE 53  53  53  ILE ILE A . n 
A 1 54  SER 54  54  54  SER SER A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  LEU 56  56  56  LEU LEU A . n 
A 1 57  ASP 57  57  57  ASP ASP A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  GLU 60  60  60  GLU GLU A . n 
A 1 61  GLY 61  61  61  GLY GLY A . n 
A 1 62  ILE 62  62  62  ILE ILE A . n 
A 1 63  ARG 63  63  63  ARG ARG A . n 
A 1 64  PHE 64  64  64  PHE PHE A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  TYR 67  67  67  TYR TYR A . n 
A 1 68  THR 68  68  68  THR THR A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  PRO 70  70  70  PRO PRO A . n 
A 1 71  GLU 71  71  71  GLU GLU A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  LYS 75  75  75  LYS LYS A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  PRO 77  77  77  PRO PRO A . n 
A 1 78  LYS 78  78  78  LYS LYS A . n 
A 1 79  VAL 79  79  79  VAL VAL A . n 
A 1 80  PRO 80  80  80  PRO PRO A . n 
A 1 81  GLY 81  81  81  GLY GLY A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  GLU 83  83  83  GLU GLU A . n 
A 1 84  MET 84  84  84  MET MET A . n 
A 1 85  PRO 85  85  85  PRO PRO A . n 
A 1 86  TYR 86  86  86  TYR TYR A . n 
A 1 87  VAL 87  87  87  VAL VAL A . n 
A 1 88  GLU 88  88  88  GLU GLU A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  HIS 90  90  90  HIS HIS A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  TYR 92  92  92  TYR TYR A . n 
A 1 93  LEU 93  93  93  LEU LEU A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  THR 96  96  96  THR THR A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  ASP 98  98  98  ASP ASP A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 PRO 100 100 100 PRO PRO A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 LYS 103 103 103 LYS LYS A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 VAL 105 105 105 VAL VAL A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 GLU 107 107 107 GLU GLU A . n 
A 1 108 VAL 108 108 108 VAL VAL A . n 
A 1 109 ALA 109 109 109 ALA ALA A . n 
A 1 110 GLU 110 110 110 GLU GLU A . n 
A 1 111 GLU 111 111 111 GLU GLU A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 LYS 113 113 113 LYS LYS A . n 
A 1 114 LYS 114 114 114 LYS LYS A . n 
A 1 115 ARG 115 115 115 ARG ARG A . n 
A 1 116 ARG 116 116 116 ARG ARG A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 PRO 119 119 119 PRO PRO A . n 
A 1 120 GLU 120 120 120 GLU GLU A . n 
A 1 121 TYR 121 121 121 TYR TYR A . n 
A 1 122 VAL 122 122 122 VAL VAL A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 ASP 124 124 124 ASP ASP A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 LYS 127 127 127 LYS LYS A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 MET 129 129 129 MET MET A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 THR 133 133 133 THR THR A . n 
A 1 134 HIS 134 134 134 HIS HIS A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 THR 137 137 137 THR THR A . n 
A 1 138 MET 138 138 138 MET MET A . n 
A 1 139 PHE 139 139 139 PHE PHE A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ALA 141 141 141 ALA ALA A . n 
A 1 142 GLY 142 142 142 GLY GLY A . n 
A 1 143 ILE 143 143 143 ILE ILE A . n 
A 1 144 LEU 144 144 144 LEU LEU A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 MET 146 146 146 MET MET A . n 
A 1 147 GLN 147 147 147 GLN GLN A . n 
A 1 148 ARG 148 148 148 ARG ARG A . n 
A 1 149 GLU 149 149 149 GLU GLU A . n 
A 1 150 SER 150 150 150 SER SER A . n 
A 1 151 LYS 151 151 151 LYS LYS A . n 
A 1 152 PHE 152 152 152 PHE PHE A . n 
A 1 153 ALA 153 153 153 ALA ALA A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 TYR 156 156 156 TYR TYR A . n 
A 1 157 ASN 157 157 157 ASN ASN A . n 
A 1 158 ALA 158 158 158 ALA ALA A . n 
A 1 159 GLY 159 159 159 GLY GLY A . n 
A 1 160 LYS 160 160 160 LYS LYS A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 ASN 162 162 162 ASN ASN A . n 
A 1 163 LYS 163 163 163 LYS LYS A . n 
A 1 164 ASN 164 164 164 ASN ASN A . n 
A 1 165 THR 165 165 165 THR THR A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 TRP 167 167 167 TRP TRP A . n 
A 1 168 GLU 168 168 168 GLU GLU A . n 
A 1 169 PRO 169 169 169 PRO PRO A . n 
A 1 170 MET 170 170 170 MET MET A . n 
A 1 171 PHE 171 171 171 PHE PHE A . n 
A 1 172 GLU 172 172 172 GLU GLU A . n 
A 1 173 ASP 173 173 173 ASP ASP A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 MET 175 175 175 MET MET A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 MET 178 178 178 MET MET A . n 
A 1 179 ALA 179 179 179 ALA ALA A . n 
A 1 180 LYS 180 180 180 LYS LYS A . n 
A 1 181 LEU 181 181 181 LEU LEU A . n 
A 1 182 PRO 182 182 182 PRO PRO A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 ALA 186 186 186 ALA ALA A . n 
A 1 187 TYR 187 187 187 TYR TYR A . n 
A 1 188 ILE 188 188 188 ILE ILE A . n 
A 1 189 TYR 189 189 189 TYR TYR A . n 
A 1 190 ARG 190 190 190 ARG ARG A . n 
A 1 191 MET 191 191 191 MET MET A . n 
A 1 192 LYS 192 192 192 LYS LYS A . n 
A 1 193 TYR 193 193 193 TYR TYR A . n 
A 1 194 LYS 194 194 194 LYS LYS A . n 
A 1 195 SER 195 195 195 SER SER A . n 
A 1 196 ASP 196 196 196 ASP ASP A . n 
A 1 197 THR 197 197 197 THR THR A . n 
A 1 198 HIS 198 198 198 HIS HIS A . n 
A 1 199 ILE 199 199 199 ILE ILE A . n 
A 1 200 PRO 200 200 200 PRO PRO A . n 
A 1 201 SER 201 201 201 SER SER A . n 
A 1 202 ASN 202 202 202 ASN ASN A . n 
A 1 203 PRO 203 203 203 PRO PRO A . n 
A 1 204 ASP 204 204 204 ASP ASP A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 ASP 206 206 206 ASP ASP A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 ASP 210 210 210 ASP ASP A . n 
A 1 211 PHE 211 211 211 PHE PHE A . n 
A 1 212 ALA 212 212 212 ALA ALA A . n 
A 1 213 ASN 213 213 213 ASN ASN A . n 
A 1 214 MET 214 214 214 MET MET A . n 
A 1 215 MET 215 215 215 MET MET A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 LYS 219 219 219 LYS LYS A . n 
A 1 220 PRO 220 220 220 PRO PRO A . n 
A 1 221 TYR 221 221 221 TYR TYR A . n 
A 1 222 ASP 222 222 222 ASP ASP A . n 
A 1 223 ASP 223 223 223 ASP ASP A . n 
A 1 224 VAL 224 224 224 VAL VAL A . n 
A 1 225 ALA 225 225 225 ALA ALA A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 TYR 228 228 228 TYR TYR A . n 
A 1 229 PHE 229 229 229 PHE PHE A . n 
A 1 230 ILE 230 230 230 ILE ILE A . n 
A 1 231 LEU 231 231 231 LEU LEU A . n 
A 1 232 HIS 232 232 232 HIS HIS A . n 
A 1 233 SER 233 233 233 SER SER A . n 
A 1 234 ASP 234 234 234 ASP ASP A . n 
A 1 235 HIS 235 235 235 HIS HIS A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 ASN 239 239 239 ASN ASN A . n 
A 1 240 VAL 240 240 240 VAL VAL A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 ALA 242 242 242 ALA ALA A . n 
A 1 243 HIS 243 243 243 HIS HIS A . n 
A 1 244 THR 244 244 244 THR THR A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 VAL 248 248 248 VAL VAL A . n 
A 1 249 ALA 249 249 249 ALA ALA A . n 
A 1 250 SER 250 250 250 SER SER A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 LEU 252 252 252 LEU LEU A . n 
A 1 253 SER 253 253 253 SER SER A . n 
A 1 254 ASP 254 254 254 ASP ASP A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 TYR 256 256 256 TYR TYR A . n 
A 1 257 TYR 257 257 257 TYR TYR A . n 
A 1 258 ALA 258 258 258 ALA ALA A . n 
A 1 259 TYR 259 259 259 TYR TYR A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 ALA 261 261 261 ALA ALA A . n 
A 1 262 ALA 262 262 262 ALA ALA A . n 
A 1 263 MET 263 263 263 MET MET A . n 
A 1 264 CYS 264 264 264 CYS CYS A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 PRO 269 269 269 PRO PRO A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 HIS 271 271 271 HIS HIS A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 ALA 274 274 274 ALA ALA A . n 
A 1 275 ASN 275 275 275 ASN ASN A . n 
A 1 276 GLN 276 276 276 GLN GLN A . n 
A 1 277 GLU 277 277 277 GLU GLU A . n 
A 1 278 VAL 278 278 278 VAL VAL A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 TRP 281 281 281 TRP TRP A . n 
A 1 282 ILE 282 282 282 ILE ILE A . n 
A 1 283 GLN 283 283 283 GLN GLN A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 ASP 287 287 287 ASP ASP A . n 
A 1 288 LYS 288 288 288 LYS LYS A . n 
A 1 289 LYS 289 289 289 LYS LYS A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 LYS 293 293 293 LYS LYS A . n 
A 1 294 VAL 294 294 294 VAL VAL A . n 
A 1 295 PRO 295 295 295 PRO PRO A . n 
A 1 296 THR 296 296 296 THR THR A . n 
A 1 297 LYS 297 297 297 LYS LYS A . n 
A 1 298 GLU 298 298 298 GLU GLU A . n 
A 1 299 GLU 299 299 299 GLU GLU A . n 
A 1 300 LEU 300 300 300 LEU LEU A . n 
A 1 301 LYS 301 301 301 LYS LYS A . n 
A 1 302 LYS 302 302 302 LYS LYS A . n 
A 1 303 PHE 303 303 303 PHE PHE A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 GLU 305 305 305 GLU GLU A . n 
A 1 306 GLU 306 306 306 GLU GLU A . n 
A 1 307 THR 307 307 307 THR THR A . n 
A 1 308 LEU 308 308 308 LEU LEU A . n 
A 1 309 SER 309 309 309 SER SER A . n 
A 1 310 SER 310 310 310 SER SER A . n 
A 1 311 GLY 311 311 311 GLY GLY A . n 
A 1 312 GLN 312 312 312 GLN GLN A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 ILE 314 314 314 ILE ILE A . n 
A 1 315 PRO 315 315 315 PRO PRO A . n 
A 1 316 GLY 316 316 316 GLY GLY A . n 
A 1 317 TYR 317 317 317 TYR TYR A . n 
A 1 318 GLY 318 318 318 GLY GLY A . n 
A 1 319 HIS 319 319 319 HIS HIS A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 VAL 321 321 321 VAL VAL A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 ARG 323 323 323 ARG ARG A . n 
A 1 324 LYS 324 324 324 LYS LYS A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 ASP 326 326 326 ASP ASP A . n 
A 1 327 PRO 327 327 327 PRO PRO A . n 
A 1 328 ARG 328 328 328 ARG ARG A . n 
A 1 329 TYR 329 329 329 TYR TYR A . n 
A 1 330 VAL 330 330 330 VAL VAL A . n 
A 1 331 ALA 331 331 331 ALA ALA A . n 
A 1 332 GLN 332 332 332 GLN GLN A . n 
A 1 333 ARG 333 333 333 ARG ARG A . n 
A 1 334 GLU 334 334 334 GLU GLU A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 ALA 336 336 336 ALA ALA A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 LYS 338 338 338 LYS LYS A . n 
A 1 339 HIS 339 339 339 HIS HIS A . n 
A 1 340 MET 340 340 340 MET MET A . n 
A 1 341 PRO 341 341 341 PRO PRO A . n 
A 1 342 ASP 342 342 342 ASP ASP A . n 
A 1 343 ASP 343 343 343 ASP ASP A . n 
A 1 344 PRO 344 344 344 PRO PRO A . n 
A 1 345 ILE 345 345 345 ILE ILE A . n 
A 1 346 PHE 346 346 346 PHE PHE A . n 
A 1 347 GLN 347 347 347 GLN GLN A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 SER 350 350 350 SER SER A . n 
A 1 351 MET 351 351 351 MET MET A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 TYR 353 353 353 TYR TYR A . n 
A 1 354 GLU 354 354 354 GLU GLU A . n 
A 1 355 VAL 355 355 355 VAL VAL A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 PRO 357 357 357 PRO PRO A . n 
A 1 358 PRO 358 358 358 PRO PRO A . n 
A 1 359 ILE 359 359 359 ILE ILE A . n 
A 1 360 LEU 360 360 360 LEU LEU A . n 
A 1 361 SER 361 361 361 SER SER A . n 
A 1 362 SER 362 362 362 SER SER A . n 
A 1 363 LEU 363 363 363 LEU LEU A . n 
A 1 364 GLY 364 364 364 GLY GLY A . n 
A 1 365 LYS 365 365 365 LYS LYS A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 LYS 367 367 367 LYS LYS A . n 
A 1 368 ASP 368 368 368 ASP ASP A . n 
A 1 369 PRO 369 369 369 PRO PRO A . n 
A 1 370 TRP 370 370 370 TRP TRP A . n 
A 1 371 PRO 371 371 371 PRO PRO A . n 
A 1 372 ASN 372 372 372 ASN ASN A . n 
A 1 373 VAL 373 373 373 VAL VAL A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 ALA 375 375 375 ALA ALA A . n 
A 1 376 HIS 376 376 376 HIS HIS A . n 
A 1 377 SER 377 377 377 SER SER A . n 
A 1 378 GLY 378 378 378 GLY GLY A . n 
A 1 379 CYS 379 379 379 CYS CYS A . n 
A 1 380 ILE 380 380 380 ILE ILE A . n 
A 1 381 GLN 381 381 381 GLN GLN A . n 
A 1 382 TRP 382 382 382 TRP TRP A . n 
A 1 383 HIS 383 383 383 HIS HIS A . n 
A 1 384 TYR 384 384 384 TYR TYR A . n 
A 1 385 GLY 385 385 385 GLY GLY A . n 
A 1 386 VAL 386 386 386 VAL VAL A . n 
A 1 387 VAL 387 387 387 VAL VAL A . n 
A 1 388 GLU 388 388 388 GLU GLU A . n 
A 1 389 TYR 389 389 389 TYR TYR A . n 
A 1 390 ASP 390 390 390 ASP ASP A . n 
A 1 391 PHE 391 391 391 PHE PHE A . n 
A 1 392 TYR 392 392 392 TYR TYR A . n 
A 1 393 THR 393 393 393 THR THR A . n 
A 1 394 VAL 394 394 394 VAL VAL A . n 
A 1 395 LEU 395 395 395 LEU LEU A . n 
A 1 396 PHE 396 396 396 PHE PHE A . n 
A 1 397 GLY 397 397 397 GLY GLY A . n 
A 1 398 ILE 398 398 398 ILE ILE A . n 
A 1 399 GLY 399 399 399 GLY GLY A . n 
A 1 400 ARG 400 400 400 ARG ARG A . n 
A 1 401 ALA 401 401 401 ALA ALA A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 GLY 403 403 403 GLY GLY A . n 
A 1 404 VAL 404 404 404 VAL VAL A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 ALA 406 406 406 ALA ALA A . n 
A 1 407 ASN 407 407 407 ASN ASN A . n 
A 1 408 LEU 408 408 408 LEU LEU A . n 
A 1 409 VAL 409 409 409 VAL VAL A . n 
A 1 410 TRP 410 410 410 TRP TRP A . n 
A 1 411 ASP 411 411 411 ASP ASP A . n 
A 1 412 ARG 412 412 412 ARG ARG A . n 
A 1 413 ALA 413 413 413 ALA ALA A . n 
A 1 414 LEU 414 414 414 LEU LEU A . n 
A 1 415 GLY 415 415 415 GLY GLY A . n 
A 1 416 TYR 416 416 416 TYR TYR A . n 
A 1 417 ALA 417 417 417 ALA ALA A . n 
A 1 418 ILE 418 418 418 ILE ILE A . n 
A 1 419 GLU 419 419 419 GLU GLU A . n 
A 1 420 ARG 420 420 420 ARG ARG A . n 
A 1 421 PRO 421 421 421 PRO PRO A . n 
A 1 422 LYS 422 422 422 LYS LYS A . n 
A 1 423 SER 423 423 423 SER SER A . n 
A 1 424 VAL 424 424 424 VAL VAL A . n 
A 1 425 THR 425 425 425 THR THR A . n 
A 1 426 THR 426 426 426 THR THR A . n 
A 1 427 ASP 427 427 427 ASP ASP A . n 
A 1 428 MET 428 428 428 MET MET A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 GLU 430 430 430 GLU GLU A . n 
A 1 431 LYS 431 431 431 LYS LYS A . n 
A 1 432 TRP 432 432 432 TRP TRP A . n 
A 1 433 ALA 433 433 433 ALA ALA A . n 
A 1 434 GLY 434 434 434 GLY GLY A . n 
A 1 435 ILE 435 435 435 ILE ILE A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   SER 2   2   2   SER SER B . n 
B 1 3   PHE 3   3   3   PHE PHE B . n 
B 1 4   LEU 4   4   4   LEU LEU B . n 
B 1 5   LYS 5   5   5   LYS LYS B . n 
B 1 6   GLU 6   6   6   GLU GLU B . n 
B 1 7   LYS 7   7   7   LYS LYS B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   ALA 9   9   9   ALA ALA B . n 
B 1 10  GLU 10  10  10  GLU GLU B . n 
B 1 11  LYS 11  11  11  LYS LYS B . n 
B 1 12  ILE 12  12  12  ILE ILE B . n 
B 1 13  ALA 13  13  13  ALA ALA B . n 
B 1 14  GLN 14  14  14  GLN GLN B . n 
B 1 15  HIS 15  15  15  HIS HIS B . n 
B 1 16  ARG 16  16  16  ARG ARG B . n 
B 1 17  PRO 17  17  17  PRO PRO B . n 
B 1 18  ARG 18  18  18  ARG ARG B . n 
B 1 19  THR 19  19  19  THR THR B . n 
B 1 20  THR 20  20  20  THR THR B . n 
B 1 21  ARG 21  21  21  ARG ARG B . n 
B 1 22  LEU 22  22  22  LEU LEU B . n 
B 1 23  LEU 23  23  23  LEU LEU B . n 
B 1 24  LYS 24  24  24  LYS LYS B . n 
B 1 25  GLU 25  25  25  GLU GLU B . n 
B 1 26  PHE 26  26  26  PHE PHE B . n 
B 1 27  GLY 27  27  27  GLY GLY B . n 
B 1 28  ASN 28  28  28  ASN ASN B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  LYS 30  30  30  LYS LYS B . n 
B 1 31  ILE 31  31  31  ILE ILE B . n 
B 1 32  ASP 32  32  32  ASP ASP B . n 
B 1 33  GLU 33  33  33  GLU GLU B . n 
B 1 34  VAL 34  34  34  VAL VAL B . n 
B 1 35  THR 35  35  35  THR THR B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  SER 37  37  37  SER SER B . n 
B 1 38  GLN 38  38  38  GLN GLN B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  ILE 40  40  40  ILE ILE B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  GLY 42  42  42  GLY GLY B . n 
B 1 43  MET 43  43  43  MET MET B . n 
B 1 44  ARG 44  44  44  ARG ARG B . n 
B 1 45  GLY 45  45  45  GLY GLY B . n 
B 1 46  ILE 46  46  46  ILE ILE B . n 
B 1 47  LYS 47  47  47  LYS LYS B . n 
B 1 48  SER 48  48  48  SER SER B . n 
B 1 49  LEU 49  49  49  LEU LEU B . n 
B 1 50  VAL 50  50  50  VAL VAL B . n 
B 1 51  THR 51  51  51  THR THR B . n 
B 1 52  ASP 52  52  52  ASP ASP B . n 
B 1 53  ILE 53  53  53  ILE ILE B . n 
B 1 54  SER 54  54  54  SER SER B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  LEU 56  56  56  LEU LEU B . n 
B 1 57  ASP 57  57  57  ASP ASP B . n 
B 1 58  PRO 58  58  58  PRO PRO B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  GLU 60  60  60  GLU GLU B . n 
B 1 61  GLY 61  61  61  GLY GLY B . n 
B 1 62  ILE 62  62  62  ILE ILE B . n 
B 1 63  ARG 63  63  63  ARG ARG B . n 
B 1 64  PHE 64  64  64  PHE PHE B . n 
B 1 65  ARG 65  65  65  ARG ARG B . n 
B 1 66  GLY 66  66  66  GLY GLY B . n 
B 1 67  TYR 67  67  67  TYR TYR B . n 
B 1 68  THR 68  68  68  THR THR B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  PRO 70  70  70  PRO PRO B . n 
B 1 71  GLU 71  71  71  GLU GLU B . n 
B 1 72  VAL 72  72  72  VAL VAL B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  GLU 74  74  74  GLU GLU B . n 
B 1 75  LYS 75  75  75  LYS LYS B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  PRO 77  77  77  PRO PRO B . n 
B 1 78  LYS 78  78  78  LYS LYS B . n 
B 1 79  VAL 79  79  79  VAL VAL B . n 
B 1 80  PRO 80  80  80  PRO PRO B . n 
B 1 81  GLY 81  81  81  GLY GLY B . n 
B 1 82  ALA 82  82  82  ALA ALA B . n 
B 1 83  GLU 83  83  83  GLU GLU B . n 
B 1 84  MET 84  84  84  MET MET B . n 
B 1 85  PRO 85  85  85  PRO PRO B . n 
B 1 86  TYR 86  86  86  TYR TYR B . n 
B 1 87  VAL 87  87  87  VAL VAL B . n 
B 1 88  GLU 88  88  88  GLU GLU B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  HIS 90  90  90  HIS HIS B . n 
B 1 91  PHE 91  91  91  PHE PHE B . n 
B 1 92  TYR 92  92  92  TYR TYR B . n 
B 1 93  LEU 93  93  93  LEU LEU B . n 
B 1 94  LEU 94  94  94  LEU LEU B . n 
B 1 95  LEU 95  95  95  LEU LEU B . n 
B 1 96  THR 96  96  96  THR THR B . n 
B 1 97  GLY 97  97  97  GLY GLY B . n 
B 1 98  ASP 98  98  98  ASP ASP B . n 
B 1 99  VAL 99  99  99  VAL VAL B . n 
B 1 100 PRO 100 100 100 PRO PRO B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 GLU 102 102 102 GLU GLU B . n 
B 1 103 LYS 103 103 103 LYS LYS B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 VAL 105 105 105 VAL VAL B . n 
B 1 106 LYS 106 106 106 LYS LYS B . n 
B 1 107 GLU 107 107 107 GLU GLU B . n 
B 1 108 VAL 108 108 108 VAL VAL B . n 
B 1 109 ALA 109 109 109 ALA ALA B . n 
B 1 110 GLU 110 110 110 GLU GLU B . n 
B 1 111 GLU 111 111 111 GLU GLU B . n 
B 1 112 PHE 112 112 112 PHE PHE B . n 
B 1 113 LYS 113 113 113 LYS LYS B . n 
B 1 114 LYS 114 114 114 LYS LYS B . n 
B 1 115 ARG 115 115 115 ARG ARG B . n 
B 1 116 ARG 116 116 116 ARG ARG B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 PRO 119 119 119 PRO PRO B . n 
B 1 120 GLU 120 120 120 GLU GLU B . n 
B 1 121 TYR 121 121 121 TYR TYR B . n 
B 1 122 VAL 122 122 122 VAL VAL B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 ASP 124 124 124 ASP ASP B . n 
B 1 125 THR 125 125 125 THR THR B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 LYS 127 127 127 LYS LYS B . n 
B 1 128 ALA 128 128 128 ALA ALA B . n 
B 1 129 MET 129 129 129 MET MET B . n 
B 1 130 PRO 130 130 130 PRO PRO B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 ASP 132 132 132 ASP ASP B . n 
B 1 133 THR 133 133 133 THR THR B . n 
B 1 134 HIS 134 134 134 HIS HIS B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 MET 136 136 136 MET MET B . n 
B 1 137 THR 137 137 137 THR THR B . n 
B 1 138 MET 138 138 138 MET MET B . n 
B 1 139 PHE 139 139 139 PHE PHE B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 ALA 141 141 141 ALA ALA B . n 
B 1 142 GLY 142 142 142 GLY GLY B . n 
B 1 143 ILE 143 143 143 ILE ILE B . n 
B 1 144 LEU 144 144 144 LEU LEU B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 MET 146 146 146 MET MET B . n 
B 1 147 GLN 147 147 147 GLN GLN B . n 
B 1 148 ARG 148 148 148 ARG ARG B . n 
B 1 149 GLU 149 149 149 GLU GLU B . n 
B 1 150 SER 150 150 150 SER SER B . n 
B 1 151 LYS 151 151 151 LYS LYS B . n 
B 1 152 PHE 152 152 152 PHE PHE B . n 
B 1 153 ALA 153 153 153 ALA ALA B . n 
B 1 154 ALA 154 154 154 ALA ALA B . n 
B 1 155 TYR 155 155 155 TYR TYR B . n 
B 1 156 TYR 156 156 156 TYR TYR B . n 
B 1 157 ASN 157 157 157 ASN ASN B . n 
B 1 158 ALA 158 158 158 ALA ALA B . n 
B 1 159 GLY 159 159 159 GLY GLY B . n 
B 1 160 LYS 160 160 160 LYS LYS B . n 
B 1 161 PHE 161 161 161 PHE PHE B . n 
B 1 162 ASN 162 162 162 ASN ASN B . n 
B 1 163 LYS 163 163 163 LYS LYS B . n 
B 1 164 ASN 164 164 164 ASN ASN B . n 
B 1 165 THR 165 165 165 THR THR B . n 
B 1 166 ALA 166 166 166 ALA ALA B . n 
B 1 167 TRP 167 167 167 TRP TRP B . n 
B 1 168 GLU 168 168 168 GLU GLU B . n 
B 1 169 PRO 169 169 169 PRO PRO B . n 
B 1 170 MET 170 170 170 MET MET B . n 
B 1 171 PHE 171 171 171 PHE PHE B . n 
B 1 172 GLU 172 172 172 GLU GLU B . n 
B 1 173 ASP 173 173 173 ASP ASP B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 MET 175 175 175 MET MET B . n 
B 1 176 ASP 176 176 176 ASP ASP B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 MET 178 178 178 MET MET B . n 
B 1 179 ALA 179 179 179 ALA ALA B . n 
B 1 180 LYS 180 180 180 LYS LYS B . n 
B 1 181 LEU 181 181 181 LEU LEU B . n 
B 1 182 PRO 182 182 182 PRO PRO B . n 
B 1 183 SER 183 183 183 SER SER B . n 
B 1 184 LEU 184 184 184 LEU LEU B . n 
B 1 185 GLY 185 185 185 GLY GLY B . n 
B 1 186 ALA 186 186 186 ALA ALA B . n 
B 1 187 TYR 187 187 187 TYR TYR B . n 
B 1 188 ILE 188 188 188 ILE ILE B . n 
B 1 189 TYR 189 189 189 TYR TYR B . n 
B 1 190 ARG 190 190 190 ARG ARG B . n 
B 1 191 MET 191 191 191 MET MET B . n 
B 1 192 LYS 192 192 192 LYS LYS B . n 
B 1 193 TYR 193 193 193 TYR TYR B . n 
B 1 194 LYS 194 194 194 LYS LYS B . n 
B 1 195 SER 195 195 195 SER SER B . n 
B 1 196 ASP 196 196 196 ASP ASP B . n 
B 1 197 THR 197 197 197 THR THR B . n 
B 1 198 HIS 198 198 198 HIS HIS B . n 
B 1 199 ILE 199 199 199 ILE ILE B . n 
B 1 200 PRO 200 200 200 PRO PRO B . n 
B 1 201 SER 201 201 201 SER SER B . n 
B 1 202 ASN 202 202 202 ASN ASN B . n 
B 1 203 PRO 203 203 203 PRO PRO B . n 
B 1 204 ASP 204 204 204 ASP ASP B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 ASP 206 206 206 ASP ASP B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 GLY 208 208 208 GLY GLY B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 ASP 210 210 210 ASP ASP B . n 
B 1 211 PHE 211 211 211 PHE PHE B . n 
B 1 212 ALA 212 212 212 ALA ALA B . n 
B 1 213 ASN 213 213 213 ASN ASN B . n 
B 1 214 MET 214 214 214 MET MET B . n 
B 1 215 MET 215 215 215 MET MET B . n 
B 1 216 GLY 216 216 216 GLY GLY B . n 
B 1 217 ILE 217 217 217 ILE ILE B . n 
B 1 218 ASP 218 218 218 ASP ASP B . n 
B 1 219 LYS 219 219 219 LYS LYS B . n 
B 1 220 PRO 220 220 220 PRO PRO B . n 
B 1 221 TYR 221 221 221 TYR TYR B . n 
B 1 222 ASP 222 222 222 ASP ASP B . n 
B 1 223 ASP 223 223 223 ASP ASP B . n 
B 1 224 VAL 224 224 224 VAL VAL B . n 
B 1 225 ALA 225 225 225 ALA ALA B . n 
B 1 226 ARG 226 226 226 ARG ARG B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 TYR 228 228 228 TYR TYR B . n 
B 1 229 PHE 229 229 229 PHE PHE B . n 
B 1 230 ILE 230 230 230 ILE ILE B . n 
B 1 231 LEU 231 231 231 LEU LEU B . n 
B 1 232 HIS 232 232 232 HIS HIS B . n 
B 1 233 SER 233 233 233 SER SER B . n 
B 1 234 ASP 234 234 234 ASP ASP B . n 
B 1 235 HIS 235 235 235 HIS HIS B . n 
B 1 236 GLU 236 236 236 GLU GLU B . n 
B 1 237 SER 237 237 237 SER SER B . n 
B 1 238 GLY 238 238 238 GLY GLY B . n 
B 1 239 ASN 239 239 239 ASN ASN B . n 
B 1 240 VAL 240 240 240 VAL VAL B . n 
B 1 241 SER 241 241 241 SER SER B . n 
B 1 242 ALA 242 242 242 ALA ALA B . n 
B 1 243 HIS 243 243 243 HIS HIS B . n 
B 1 244 THR 244 244 244 THR THR B . n 
B 1 245 ALA 245 245 245 ALA ALA B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 LEU 247 247 247 LEU LEU B . n 
B 1 248 VAL 248 248 248 VAL VAL B . n 
B 1 249 ALA 249 249 249 ALA ALA B . n 
B 1 250 SER 250 250 250 SER SER B . n 
B 1 251 ALA 251 251 251 ALA ALA B . n 
B 1 252 LEU 252 252 252 LEU LEU B . n 
B 1 253 SER 253 253 253 SER SER B . n 
B 1 254 ASP 254 254 254 ASP ASP B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 TYR 256 256 256 TYR TYR B . n 
B 1 257 TYR 257 257 257 TYR TYR B . n 
B 1 258 ALA 258 258 258 ALA ALA B . n 
B 1 259 TYR 259 259 259 TYR TYR B . n 
B 1 260 SER 260 260 260 SER SER B . n 
B 1 261 ALA 261 261 261 ALA ALA B . n 
B 1 262 ALA 262 262 262 ALA ALA B . n 
B 1 263 MET 263 263 263 MET MET B . n 
B 1 264 CYS 264 264 264 CYS CYS B . n 
B 1 265 GLY 265 265 265 GLY GLY B . n 
B 1 266 LEU 266 266 266 LEU LEU B . n 
B 1 267 ALA 267 267 267 ALA ALA B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 PRO 269 269 269 PRO PRO B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 HIS 271 271 271 HIS HIS B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 ALA 274 274 274 ALA ALA B . n 
B 1 275 ASN 275 275 275 ASN ASN B . n 
B 1 276 GLN 276 276 276 GLN GLN B . n 
B 1 277 GLU 277 277 277 GLU GLU B . n 
B 1 278 VAL 278 278 278 VAL VAL B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 LYS 280 280 280 LYS LYS B . n 
B 1 281 TRP 281 281 281 TRP TRP B . n 
B 1 282 ILE 282 282 282 ILE ILE B . n 
B 1 283 GLN 283 283 283 GLN GLN B . n 
B 1 284 GLU 284 284 284 GLU GLU B . n 
B 1 285 THR 285 285 285 THR THR B . n 
B 1 286 ILE 286 286 286 ILE ILE B . n 
B 1 287 ASP 287 287 287 ASP ASP B . n 
B 1 288 LYS 288 288 288 LYS LYS B . n 
B 1 289 LYS 289 289 289 LYS LYS B . n 
B 1 290 LEU 290 290 290 LEU LEU B . n 
B 1 291 GLY 291 291 291 GLY GLY B . n 
B 1 292 GLY 292 292 292 GLY GLY B . n 
B 1 293 LYS 293 293 293 LYS LYS B . n 
B 1 294 VAL 294 294 294 VAL VAL B . n 
B 1 295 PRO 295 295 295 PRO PRO B . n 
B 1 296 THR 296 296 296 THR THR B . n 
B 1 297 LYS 297 297 297 LYS LYS B . n 
B 1 298 GLU 298 298 298 GLU GLU B . n 
B 1 299 GLU 299 299 299 GLU GLU B . n 
B 1 300 LEU 300 300 300 LEU LEU B . n 
B 1 301 LYS 301 301 301 LYS LYS B . n 
B 1 302 LYS 302 302 302 LYS LYS B . n 
B 1 303 PHE 303 303 303 PHE PHE B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 GLU 305 305 305 GLU GLU B . n 
B 1 306 GLU 306 306 306 GLU GLU B . n 
B 1 307 THR 307 307 307 THR THR B . n 
B 1 308 LEU 308 308 308 LEU LEU B . n 
B 1 309 SER 309 309 309 SER SER B . n 
B 1 310 SER 310 310 310 SER SER B . n 
B 1 311 GLY 311 311 311 GLY GLY B . n 
B 1 312 GLN 312 312 312 GLN GLN B . n 
B 1 313 VAL 313 313 313 VAL VAL B . n 
B 1 314 ILE 314 314 314 ILE ILE B . n 
B 1 315 PRO 315 315 315 PRO PRO B . n 
B 1 316 GLY 316 316 316 GLY GLY B . n 
B 1 317 TYR 317 317 317 TYR TYR B . n 
B 1 318 GLY 318 318 318 GLY GLY B . n 
B 1 319 HIS 319 319 319 HIS HIS B . n 
B 1 320 ALA 320 320 320 ALA ALA B . n 
B 1 321 VAL 321 321 321 VAL VAL B . n 
B 1 322 LEU 322 322 322 LEU LEU B . n 
B 1 323 ARG 323 323 323 ARG ARG B . n 
B 1 324 LYS 324 324 324 LYS LYS B . n 
B 1 325 THR 325 325 325 THR THR B . n 
B 1 326 ASP 326 326 326 ASP ASP B . n 
B 1 327 PRO 327 327 327 PRO PRO B . n 
B 1 328 ARG 328 328 328 ARG ARG B . n 
B 1 329 TYR 329 329 329 TYR TYR B . n 
B 1 330 VAL 330 330 330 VAL VAL B . n 
B 1 331 ALA 331 331 331 ALA ALA B . n 
B 1 332 GLN 332 332 332 GLN GLN B . n 
B 1 333 ARG 333 333 333 ARG ARG B . n 
B 1 334 GLU 334 334 334 GLU GLU B . n 
B 1 335 PHE 335 335 335 PHE PHE B . n 
B 1 336 ALA 336 336 336 ALA ALA B . n 
B 1 337 LEU 337 337 337 LEU LEU B . n 
B 1 338 LYS 338 338 338 LYS LYS B . n 
B 1 339 HIS 339 339 339 HIS HIS B . n 
B 1 340 MET 340 340 340 MET MET B . n 
B 1 341 PRO 341 341 341 PRO PRO B . n 
B 1 342 ASP 342 342 342 ASP ASP B . n 
B 1 343 ASP 343 343 343 ASP ASP B . n 
B 1 344 PRO 344 344 344 PRO PRO B . n 
B 1 345 ILE 345 345 345 ILE ILE B . n 
B 1 346 PHE 346 346 346 PHE PHE B . n 
B 1 347 GLN 347 347 347 GLN GLN B . n 
B 1 348 VAL 348 348 348 VAL VAL B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 SER 350 350 350 SER SER B . n 
B 1 351 MET 351 351 351 MET MET B . n 
B 1 352 LEU 352 352 352 LEU LEU B . n 
B 1 353 TYR 353 353 353 TYR TYR B . n 
B 1 354 GLU 354 354 354 GLU GLU B . n 
B 1 355 VAL 355 355 355 VAL VAL B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 PRO 357 357 357 PRO PRO B . n 
B 1 358 PRO 358 358 358 PRO PRO B . n 
B 1 359 ILE 359 359 359 ILE ILE B . n 
B 1 360 LEU 360 360 360 LEU LEU B . n 
B 1 361 SER 361 361 361 SER SER B . n 
B 1 362 SER 362 362 362 SER SER B . n 
B 1 363 LEU 363 363 363 LEU LEU B . n 
B 1 364 GLY 364 364 364 GLY GLY B . n 
B 1 365 LYS 365 365 365 LYS LYS B . n 
B 1 366 VAL 366 366 366 VAL VAL B . n 
B 1 367 LYS 367 367 367 LYS LYS B . n 
B 1 368 ASP 368 368 368 ASP ASP B . n 
B 1 369 PRO 369 369 369 PRO PRO B . n 
B 1 370 TRP 370 370 370 TRP TRP B . n 
B 1 371 PRO 371 371 371 PRO PRO B . n 
B 1 372 ASN 372 372 372 ASN ASN B . n 
B 1 373 VAL 373 373 373 VAL VAL B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 ALA 375 375 375 ALA ALA B . n 
B 1 376 HIS 376 376 376 HIS HIS B . n 
B 1 377 SER 377 377 377 SER SER B . n 
B 1 378 GLY 378 378 378 GLY GLY B . n 
B 1 379 CYS 379 379 379 CYS CYS B . n 
B 1 380 ILE 380 380 380 ILE ILE B . n 
B 1 381 GLN 381 381 381 GLN GLN B . n 
B 1 382 TRP 382 382 382 TRP TRP B . n 
B 1 383 HIS 383 383 383 HIS HIS B . n 
B 1 384 TYR 384 384 384 TYR TYR B . n 
B 1 385 GLY 385 385 385 GLY GLY B . n 
B 1 386 VAL 386 386 386 VAL VAL B . n 
B 1 387 VAL 387 387 387 VAL VAL B . n 
B 1 388 GLU 388 388 388 GLU GLU B . n 
B 1 389 TYR 389 389 389 TYR TYR B . n 
B 1 390 ASP 390 390 390 ASP ASP B . n 
B 1 391 PHE 391 391 391 PHE PHE B . n 
B 1 392 TYR 392 392 392 TYR TYR B . n 
B 1 393 THR 393 393 393 THR THR B . n 
B 1 394 VAL 394 394 394 VAL VAL B . n 
B 1 395 LEU 395 395 395 LEU LEU B . n 
B 1 396 PHE 396 396 396 PHE PHE B . n 
B 1 397 GLY 397 397 397 GLY GLY B . n 
B 1 398 ILE 398 398 398 ILE ILE B . n 
B 1 399 GLY 399 399 399 GLY GLY B . n 
B 1 400 ARG 400 400 400 ARG ARG B . n 
B 1 401 ALA 401 401 401 ALA ALA B . n 
B 1 402 LEU 402 402 402 LEU LEU B . n 
B 1 403 GLY 403 403 403 GLY GLY B . n 
B 1 404 VAL 404 404 404 VAL VAL B . n 
B 1 405 LEU 405 405 405 LEU LEU B . n 
B 1 406 ALA 406 406 406 ALA ALA B . n 
B 1 407 ASN 407 407 407 ASN ASN B . n 
B 1 408 LEU 408 408 408 LEU LEU B . n 
B 1 409 VAL 409 409 409 VAL VAL B . n 
B 1 410 TRP 410 410 410 TRP TRP B . n 
B 1 411 ASP 411 411 411 ASP ASP B . n 
B 1 412 ARG 412 412 412 ARG ARG B . n 
B 1 413 ALA 413 413 413 ALA ALA B . n 
B 1 414 LEU 414 414 414 LEU LEU B . n 
B 1 415 GLY 415 415 415 GLY GLY B . n 
B 1 416 TYR 416 416 416 TYR TYR B . n 
B 1 417 ALA 417 417 417 ALA ALA B . n 
B 1 418 ILE 418 418 418 ILE ILE B . n 
B 1 419 GLU 419 419 419 GLU GLU B . n 
B 1 420 ARG 420 420 420 ARG ARG B . n 
B 1 421 PRO 421 421 421 PRO PRO B . n 
B 1 422 LYS 422 422 422 LYS LYS B . n 
B 1 423 SER 423 423 423 SER SER B . n 
B 1 424 VAL 424 424 424 VAL VAL B . n 
B 1 425 THR 425 425 425 THR THR B . n 
B 1 426 THR 426 426 426 THR THR B . n 
B 1 427 ASP 427 427 427 ASP ASP B . n 
B 1 428 MET 428 428 428 MET MET B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 GLU 430 430 430 GLU GLU B . n 
B 1 431 LYS 431 431 431 LYS LYS B . n 
B 1 432 TRP 432 432 432 TRP TRP B . n 
B 1 433 ALA 433 433 433 ALA ALA B . n 
B 1 434 GLY 434 434 434 GLY GLY B . n 
B 1 435 ILE 435 435 435 ILE ILE B . n 
C 1 1   MET 1   1   ?   ?   ?   C . n 
C 1 2   SER 2   2   2   SER SER C . n 
C 1 3   PHE 3   3   3   PHE PHE C . n 
C 1 4   LEU 4   4   4   LEU LEU C . n 
C 1 5   LYS 5   5   5   LYS LYS C . n 
C 1 6   GLU 6   6   6   GLU GLU C . n 
C 1 7   LYS 7   7   7   LYS LYS C . n 
C 1 8   LEU 8   8   8   LEU LEU C . n 
C 1 9   ALA 9   9   9   ALA ALA C . n 
C 1 10  GLU 10  10  10  GLU GLU C . n 
C 1 11  LYS 11  11  11  LYS LYS C . n 
C 1 12  ILE 12  12  12  ILE ILE C . n 
C 1 13  ALA 13  13  13  ALA ALA C . n 
C 1 14  GLN 14  14  14  GLN GLN C . n 
C 1 15  HIS 15  15  15  HIS HIS C . n 
C 1 16  ARG 16  16  16  ARG ARG C . n 
C 1 17  PRO 17  17  17  PRO PRO C . n 
C 1 18  ARG 18  18  18  ARG ARG C . n 
C 1 19  THR 19  19  19  THR THR C . n 
C 1 20  THR 20  20  20  THR THR C . n 
C 1 21  ARG 21  21  21  ARG ARG C . n 
C 1 22  LEU 22  22  22  LEU LEU C . n 
C 1 23  LEU 23  23  23  LEU LEU C . n 
C 1 24  LYS 24  24  24  LYS LYS C . n 
C 1 25  GLU 25  25  25  GLU GLU C . n 
C 1 26  PHE 26  26  26  PHE PHE C . n 
C 1 27  GLY 27  27  27  GLY GLY C . n 
C 1 28  ASN 28  28  28  ASN ASN C . n 
C 1 29  VAL 29  29  29  VAL VAL C . n 
C 1 30  LYS 30  30  30  LYS LYS C . n 
C 1 31  ILE 31  31  31  ILE ILE C . n 
C 1 32  ASP 32  32  32  ASP ASP C . n 
C 1 33  GLU 33  33  33  GLU GLU C . n 
C 1 34  VAL 34  34  34  VAL VAL C . n 
C 1 35  THR 35  35  35  THR THR C . n 
C 1 36  ILE 36  36  36  ILE ILE C . n 
C 1 37  SER 37  37  37  SER SER C . n 
C 1 38  GLN 38  38  38  GLN GLN C . n 
C 1 39  ALA 39  39  39  ALA ALA C . n 
C 1 40  ILE 40  40  40  ILE ILE C . n 
C 1 41  GLY 41  41  41  GLY GLY C . n 
C 1 42  GLY 42  42  42  GLY GLY C . n 
C 1 43  MET 43  43  43  MET MET C . n 
C 1 44  ARG 44  44  44  ARG ARG C . n 
C 1 45  GLY 45  45  45  GLY GLY C . n 
C 1 46  ILE 46  46  46  ILE ILE C . n 
C 1 47  LYS 47  47  47  LYS LYS C . n 
C 1 48  SER 48  48  48  SER SER C . n 
C 1 49  LEU 49  49  49  LEU LEU C . n 
C 1 50  VAL 50  50  50  VAL VAL C . n 
C 1 51  THR 51  51  51  THR THR C . n 
C 1 52  ASP 52  52  52  ASP ASP C . n 
C 1 53  ILE 53  53  53  ILE ILE C . n 
C 1 54  SER 54  54  54  SER SER C . n 
C 1 55  TYR 55  55  55  TYR TYR C . n 
C 1 56  LEU 56  56  56  LEU LEU C . n 
C 1 57  ASP 57  57  57  ASP ASP C . n 
C 1 58  PRO 58  58  58  PRO PRO C . n 
C 1 59  GLU 59  59  59  GLU GLU C . n 
C 1 60  GLU 60  60  60  GLU GLU C . n 
C 1 61  GLY 61  61  61  GLY GLY C . n 
C 1 62  ILE 62  62  62  ILE ILE C . n 
C 1 63  ARG 63  63  63  ARG ARG C . n 
C 1 64  PHE 64  64  64  PHE PHE C . n 
C 1 65  ARG 65  65  65  ARG ARG C . n 
C 1 66  GLY 66  66  66  GLY GLY C . n 
C 1 67  TYR 67  67  67  TYR TYR C . n 
C 1 68  THR 68  68  68  THR THR C . n 
C 1 69  ILE 69  69  69  ILE ILE C . n 
C 1 70  PRO 70  70  70  PRO PRO C . n 
C 1 71  GLU 71  71  71  GLU GLU C . n 
C 1 72  VAL 72  72  72  VAL VAL C . n 
C 1 73  LEU 73  73  73  LEU LEU C . n 
C 1 74  GLU 74  74  74  GLU GLU C . n 
C 1 75  LYS 75  75  75  LYS LYS C . n 
C 1 76  LEU 76  76  76  LEU LEU C . n 
C 1 77  PRO 77  77  77  PRO PRO C . n 
C 1 78  LYS 78  78  78  LYS LYS C . n 
C 1 79  VAL 79  79  79  VAL VAL C . n 
C 1 80  PRO 80  80  80  PRO PRO C . n 
C 1 81  GLY 81  81  81  GLY GLY C . n 
C 1 82  ALA 82  82  82  ALA ALA C . n 
C 1 83  GLU 83  83  83  GLU GLU C . n 
C 1 84  MET 84  84  84  MET MET C . n 
C 1 85  PRO 85  85  85  PRO PRO C . n 
C 1 86  TYR 86  86  86  TYR TYR C . n 
C 1 87  VAL 87  87  87  VAL VAL C . n 
C 1 88  GLU 88  88  88  GLU GLU C . n 
C 1 89  GLY 89  89  89  GLY GLY C . n 
C 1 90  HIS 90  90  90  HIS HIS C . n 
C 1 91  PHE 91  91  91  PHE PHE C . n 
C 1 92  TYR 92  92  92  TYR TYR C . n 
C 1 93  LEU 93  93  93  LEU LEU C . n 
C 1 94  LEU 94  94  94  LEU LEU C . n 
C 1 95  LEU 95  95  95  LEU LEU C . n 
C 1 96  THR 96  96  96  THR THR C . n 
C 1 97  GLY 97  97  97  GLY GLY C . n 
C 1 98  ASP 98  98  98  ASP ASP C . n 
C 1 99  VAL 99  99  99  VAL VAL C . n 
C 1 100 PRO 100 100 100 PRO PRO C . n 
C 1 101 THR 101 101 101 THR THR C . n 
C 1 102 GLU 102 102 102 GLU GLU C . n 
C 1 103 LYS 103 103 103 LYS LYS C . n 
C 1 104 GLU 104 104 104 GLU GLU C . n 
C 1 105 VAL 105 105 105 VAL VAL C . n 
C 1 106 LYS 106 106 106 LYS LYS C . n 
C 1 107 GLU 107 107 107 GLU GLU C . n 
C 1 108 VAL 108 108 108 VAL VAL C . n 
C 1 109 ALA 109 109 109 ALA ALA C . n 
C 1 110 GLU 110 110 110 GLU GLU C . n 
C 1 111 GLU 111 111 111 GLU GLU C . n 
C 1 112 PHE 112 112 112 PHE PHE C . n 
C 1 113 LYS 113 113 113 LYS LYS C . n 
C 1 114 LYS 114 114 114 LYS LYS C . n 
C 1 115 ARG 115 115 115 ARG ARG C . n 
C 1 116 ARG 116 116 116 ARG ARG C . n 
C 1 117 ALA 117 117 117 ALA ALA C . n 
C 1 118 LEU 118 118 118 LEU LEU C . n 
C 1 119 PRO 119 119 119 PRO PRO C . n 
C 1 120 GLU 120 120 120 GLU GLU C . n 
C 1 121 TYR 121 121 121 TYR TYR C . n 
C 1 122 VAL 122 122 122 VAL VAL C . n 
C 1 123 LYS 123 123 123 LYS LYS C . n 
C 1 124 ASP 124 124 124 ASP ASP C . n 
C 1 125 THR 125 125 125 THR THR C . n 
C 1 126 LEU 126 126 126 LEU LEU C . n 
C 1 127 LYS 127 127 127 LYS LYS C . n 
C 1 128 ALA 128 128 128 ALA ALA C . n 
C 1 129 MET 129 129 129 MET MET C . n 
C 1 130 PRO 130 130 130 PRO PRO C . n 
C 1 131 ARG 131 131 131 ARG ARG C . n 
C 1 132 ASP 132 132 132 ASP ASP C . n 
C 1 133 THR 133 133 133 THR THR C . n 
C 1 134 HIS 134 134 134 HIS HIS C . n 
C 1 135 PRO 135 135 135 PRO PRO C . n 
C 1 136 MET 136 136 136 MET MET C . n 
C 1 137 THR 137 137 137 THR THR C . n 
C 1 138 MET 138 138 138 MET MET C . n 
C 1 139 PHE 139 139 139 PHE PHE C . n 
C 1 140 ALA 140 140 140 ALA ALA C . n 
C 1 141 ALA 141 141 141 ALA ALA C . n 
C 1 142 GLY 142 142 142 GLY GLY C . n 
C 1 143 ILE 143 143 143 ILE ILE C . n 
C 1 144 LEU 144 144 144 LEU LEU C . n 
C 1 145 ALA 145 145 145 ALA ALA C . n 
C 1 146 MET 146 146 146 MET MET C . n 
C 1 147 GLN 147 147 147 GLN GLN C . n 
C 1 148 ARG 148 148 148 ARG ARG C . n 
C 1 149 GLU 149 149 149 GLU GLU C . n 
C 1 150 SER 150 150 150 SER SER C . n 
C 1 151 LYS 151 151 151 LYS LYS C . n 
C 1 152 PHE 152 152 152 PHE PHE C . n 
C 1 153 ALA 153 153 153 ALA ALA C . n 
C 1 154 ALA 154 154 154 ALA ALA C . n 
C 1 155 TYR 155 155 155 TYR TYR C . n 
C 1 156 TYR 156 156 156 TYR TYR C . n 
C 1 157 ASN 157 157 157 ASN ASN C . n 
C 1 158 ALA 158 158 158 ALA ALA C . n 
C 1 159 GLY 159 159 159 GLY GLY C . n 
C 1 160 LYS 160 160 160 LYS LYS C . n 
C 1 161 PHE 161 161 161 PHE PHE C . n 
C 1 162 ASN 162 162 162 ASN ASN C . n 
C 1 163 LYS 163 163 163 LYS LYS C . n 
C 1 164 ASN 164 164 164 ASN ASN C . n 
C 1 165 THR 165 165 165 THR THR C . n 
C 1 166 ALA 166 166 166 ALA ALA C . n 
C 1 167 TRP 167 167 167 TRP TRP C . n 
C 1 168 GLU 168 168 168 GLU GLU C . n 
C 1 169 PRO 169 169 169 PRO PRO C . n 
C 1 170 MET 170 170 170 MET MET C . n 
C 1 171 PHE 171 171 171 PHE PHE C . n 
C 1 172 GLU 172 172 172 GLU GLU C . n 
C 1 173 ASP 173 173 173 ASP ASP C . n 
C 1 174 ALA 174 174 174 ALA ALA C . n 
C 1 175 MET 175 175 175 MET MET C . n 
C 1 176 ASP 176 176 176 ASP ASP C . n 
C 1 177 LEU 177 177 177 LEU LEU C . n 
C 1 178 MET 178 178 178 MET MET C . n 
C 1 179 ALA 179 179 179 ALA ALA C . n 
C 1 180 LYS 180 180 180 LYS LYS C . n 
C 1 181 LEU 181 181 181 LEU LEU C . n 
C 1 182 PRO 182 182 182 PRO PRO C . n 
C 1 183 SER 183 183 183 SER SER C . n 
C 1 184 LEU 184 184 184 LEU LEU C . n 
C 1 185 GLY 185 185 185 GLY GLY C . n 
C 1 186 ALA 186 186 186 ALA ALA C . n 
C 1 187 TYR 187 187 187 TYR TYR C . n 
C 1 188 ILE 188 188 188 ILE ILE C . n 
C 1 189 TYR 189 189 189 TYR TYR C . n 
C 1 190 ARG 190 190 190 ARG ARG C . n 
C 1 191 MET 191 191 191 MET MET C . n 
C 1 192 LYS 192 192 192 LYS LYS C . n 
C 1 193 TYR 193 193 193 TYR TYR C . n 
C 1 194 LYS 194 194 194 LYS LYS C . n 
C 1 195 SER 195 195 195 SER SER C . n 
C 1 196 ASP 196 196 196 ASP ASP C . n 
C 1 197 THR 197 197 197 THR THR C . n 
C 1 198 HIS 198 198 198 HIS HIS C . n 
C 1 199 ILE 199 199 199 ILE ILE C . n 
C 1 200 PRO 200 200 200 PRO PRO C . n 
C 1 201 SER 201 201 201 SER SER C . n 
C 1 202 ASN 202 202 202 ASN ASN C . n 
C 1 203 PRO 203 203 203 PRO PRO C . n 
C 1 204 ASP 204 204 204 ASP ASP C . n 
C 1 205 LEU 205 205 205 LEU LEU C . n 
C 1 206 ASP 206 206 206 ASP ASP C . n 
C 1 207 LEU 207 207 207 LEU LEU C . n 
C 1 208 GLY 208 208 208 GLY GLY C . n 
C 1 209 GLY 209 209 209 GLY GLY C . n 
C 1 210 ASP 210 210 210 ASP ASP C . n 
C 1 211 PHE 211 211 211 PHE PHE C . n 
C 1 212 ALA 212 212 212 ALA ALA C . n 
C 1 213 ASN 213 213 213 ASN ASN C . n 
C 1 214 MET 214 214 214 MET MET C . n 
C 1 215 MET 215 215 215 MET MET C . n 
C 1 216 GLY 216 216 216 GLY GLY C . n 
C 1 217 ILE 217 217 217 ILE ILE C . n 
C 1 218 ASP 218 218 218 ASP ASP C . n 
C 1 219 LYS 219 219 219 LYS LYS C . n 
C 1 220 PRO 220 220 220 PRO PRO C . n 
C 1 221 TYR 221 221 221 TYR TYR C . n 
C 1 222 ASP 222 222 222 ASP ASP C . n 
C 1 223 ASP 223 223 223 ASP ASP C . n 
C 1 224 VAL 224 224 224 VAL VAL C . n 
C 1 225 ALA 225 225 225 ALA ALA C . n 
C 1 226 ARG 226 226 226 ARG ARG C . n 
C 1 227 LEU 227 227 227 LEU LEU C . n 
C 1 228 TYR 228 228 228 TYR TYR C . n 
C 1 229 PHE 229 229 229 PHE PHE C . n 
C 1 230 ILE 230 230 230 ILE ILE C . n 
C 1 231 LEU 231 231 231 LEU LEU C . n 
C 1 232 HIS 232 232 232 HIS HIS C . n 
C 1 233 SER 233 233 233 SER SER C . n 
C 1 234 ASP 234 234 234 ASP ASP C . n 
C 1 235 HIS 235 235 235 HIS HIS C . n 
C 1 236 GLU 236 236 236 GLU GLU C . n 
C 1 237 SER 237 237 237 SER SER C . n 
C 1 238 GLY 238 238 238 GLY GLY C . n 
C 1 239 ASN 239 239 239 ASN ASN C . n 
C 1 240 VAL 240 240 240 VAL VAL C . n 
C 1 241 SER 241 241 241 SER SER C . n 
C 1 242 ALA 242 242 242 ALA ALA C . n 
C 1 243 HIS 243 243 243 HIS HIS C . n 
C 1 244 THR 244 244 244 THR THR C . n 
C 1 245 ALA 245 245 245 ALA ALA C . n 
C 1 246 HIS 246 246 246 HIS HIS C . n 
C 1 247 LEU 247 247 247 LEU LEU C . n 
C 1 248 VAL 248 248 248 VAL VAL C . n 
C 1 249 ALA 249 249 249 ALA ALA C . n 
C 1 250 SER 250 250 250 SER SER C . n 
C 1 251 ALA 251 251 251 ALA ALA C . n 
C 1 252 LEU 252 252 252 LEU LEU C . n 
C 1 253 SER 253 253 253 SER SER C . n 
C 1 254 ASP 254 254 254 ASP ASP C . n 
C 1 255 ALA 255 255 255 ALA ALA C . n 
C 1 256 TYR 256 256 256 TYR TYR C . n 
C 1 257 TYR 257 257 257 TYR TYR C . n 
C 1 258 ALA 258 258 258 ALA ALA C . n 
C 1 259 TYR 259 259 259 TYR TYR C . n 
C 1 260 SER 260 260 260 SER SER C . n 
C 1 261 ALA 261 261 261 ALA ALA C . n 
C 1 262 ALA 262 262 262 ALA ALA C . n 
C 1 263 MET 263 263 263 MET MET C . n 
C 1 264 CYS 264 264 264 CYS CYS C . n 
C 1 265 GLY 265 265 265 GLY GLY C . n 
C 1 266 LEU 266 266 266 LEU LEU C . n 
C 1 267 ALA 267 267 267 ALA ALA C . n 
C 1 268 GLY 268 268 268 GLY GLY C . n 
C 1 269 PRO 269 269 269 PRO PRO C . n 
C 1 270 LEU 270 270 270 LEU LEU C . n 
C 1 271 HIS 271 271 271 HIS HIS C . n 
C 1 272 GLY 272 272 272 GLY GLY C . n 
C 1 273 LEU 273 273 273 LEU LEU C . n 
C 1 274 ALA 274 274 274 ALA ALA C . n 
C 1 275 ASN 275 275 275 ASN ASN C . n 
C 1 276 GLN 276 276 276 GLN GLN C . n 
C 1 277 GLU 277 277 277 GLU GLU C . n 
C 1 278 VAL 278 278 278 VAL VAL C . n 
C 1 279 LEU 279 279 279 LEU LEU C . n 
C 1 280 LYS 280 280 280 LYS LYS C . n 
C 1 281 TRP 281 281 281 TRP TRP C . n 
C 1 282 ILE 282 282 282 ILE ILE C . n 
C 1 283 GLN 283 283 283 GLN GLN C . n 
C 1 284 GLU 284 284 284 GLU GLU C . n 
C 1 285 THR 285 285 285 THR THR C . n 
C 1 286 ILE 286 286 286 ILE ILE C . n 
C 1 287 ASP 287 287 287 ASP ASP C . n 
C 1 288 LYS 288 288 288 LYS LYS C . n 
C 1 289 LYS 289 289 289 LYS LYS C . n 
C 1 290 LEU 290 290 290 LEU LEU C . n 
C 1 291 GLY 291 291 291 GLY GLY C . n 
C 1 292 GLY 292 292 292 GLY GLY C . n 
C 1 293 LYS 293 293 293 LYS LYS C . n 
C 1 294 VAL 294 294 294 VAL VAL C . n 
C 1 295 PRO 295 295 295 PRO PRO C . n 
C 1 296 THR 296 296 296 THR THR C . n 
C 1 297 LYS 297 297 297 LYS LYS C . n 
C 1 298 GLU 298 298 298 GLU GLU C . n 
C 1 299 GLU 299 299 299 GLU GLU C . n 
C 1 300 LEU 300 300 300 LEU LEU C . n 
C 1 301 LYS 301 301 301 LYS LYS C . n 
C 1 302 LYS 302 302 302 LYS LYS C . n 
C 1 303 PHE 303 303 303 PHE PHE C . n 
C 1 304 VAL 304 304 304 VAL VAL C . n 
C 1 305 GLU 305 305 305 GLU GLU C . n 
C 1 306 GLU 306 306 306 GLU GLU C . n 
C 1 307 THR 307 307 307 THR THR C . n 
C 1 308 LEU 308 308 308 LEU LEU C . n 
C 1 309 SER 309 309 309 SER SER C . n 
C 1 310 SER 310 310 310 SER SER C . n 
C 1 311 GLY 311 311 311 GLY GLY C . n 
C 1 312 GLN 312 312 312 GLN GLN C . n 
C 1 313 VAL 313 313 313 VAL VAL C . n 
C 1 314 ILE 314 314 314 ILE ILE C . n 
C 1 315 PRO 315 315 315 PRO PRO C . n 
C 1 316 GLY 316 316 316 GLY GLY C . n 
C 1 317 TYR 317 317 317 TYR TYR C . n 
C 1 318 GLY 318 318 318 GLY GLY C . n 
C 1 319 HIS 319 319 319 HIS HIS C . n 
C 1 320 ALA 320 320 320 ALA ALA C . n 
C 1 321 VAL 321 321 321 VAL VAL C . n 
C 1 322 LEU 322 322 322 LEU LEU C . n 
C 1 323 ARG 323 323 323 ARG ARG C . n 
C 1 324 LYS 324 324 324 LYS LYS C . n 
C 1 325 THR 325 325 325 THR THR C . n 
C 1 326 ASP 326 326 326 ASP ASP C . n 
C 1 327 PRO 327 327 327 PRO PRO C . n 
C 1 328 ARG 328 328 328 ARG ARG C . n 
C 1 329 TYR 329 329 329 TYR TYR C . n 
C 1 330 VAL 330 330 330 VAL VAL C . n 
C 1 331 ALA 331 331 331 ALA ALA C . n 
C 1 332 GLN 332 332 332 GLN GLN C . n 
C 1 333 ARG 333 333 333 ARG ARG C . n 
C 1 334 GLU 334 334 334 GLU GLU C . n 
C 1 335 PHE 335 335 335 PHE PHE C . n 
C 1 336 ALA 336 336 336 ALA ALA C . n 
C 1 337 LEU 337 337 337 LEU LEU C . n 
C 1 338 LYS 338 338 338 LYS LYS C . n 
C 1 339 HIS 339 339 339 HIS HIS C . n 
C 1 340 MET 340 340 340 MET MET C . n 
C 1 341 PRO 341 341 341 PRO PRO C . n 
C 1 342 ASP 342 342 342 ASP ASP C . n 
C 1 343 ASP 343 343 343 ASP ASP C . n 
C 1 344 PRO 344 344 344 PRO PRO C . n 
C 1 345 ILE 345 345 345 ILE ILE C . n 
C 1 346 PHE 346 346 346 PHE PHE C . n 
C 1 347 GLN 347 347 347 GLN GLN C . n 
C 1 348 VAL 348 348 348 VAL VAL C . n 
C 1 349 VAL 349 349 349 VAL VAL C . n 
C 1 350 SER 350 350 350 SER SER C . n 
C 1 351 MET 351 351 351 MET MET C . n 
C 1 352 LEU 352 352 352 LEU LEU C . n 
C 1 353 TYR 353 353 353 TYR TYR C . n 
C 1 354 GLU 354 354 354 GLU GLU C . n 
C 1 355 VAL 355 355 355 VAL VAL C . n 
C 1 356 VAL 356 356 356 VAL VAL C . n 
C 1 357 PRO 357 357 357 PRO PRO C . n 
C 1 358 PRO 358 358 358 PRO PRO C . n 
C 1 359 ILE 359 359 359 ILE ILE C . n 
C 1 360 LEU 360 360 360 LEU LEU C . n 
C 1 361 SER 361 361 361 SER SER C . n 
C 1 362 SER 362 362 362 SER SER C . n 
C 1 363 LEU 363 363 363 LEU LEU C . n 
C 1 364 GLY 364 364 364 GLY GLY C . n 
C 1 365 LYS 365 365 365 LYS LYS C . n 
C 1 366 VAL 366 366 366 VAL VAL C . n 
C 1 367 LYS 367 367 367 LYS LYS C . n 
C 1 368 ASP 368 368 368 ASP ASP C . n 
C 1 369 PRO 369 369 369 PRO PRO C . n 
C 1 370 TRP 370 370 370 TRP TRP C . n 
C 1 371 PRO 371 371 371 PRO PRO C . n 
C 1 372 ASN 372 372 372 ASN ASN C . n 
C 1 373 VAL 373 373 373 VAL VAL C . n 
C 1 374 ASP 374 374 374 ASP ASP C . n 
C 1 375 ALA 375 375 375 ALA ALA C . n 
C 1 376 HIS 376 376 376 HIS HIS C . n 
C 1 377 SER 377 377 377 SER SER C . n 
C 1 378 GLY 378 378 378 GLY GLY C . n 
C 1 379 CYS 379 379 379 CYS CYS C . n 
C 1 380 ILE 380 380 380 ILE ILE C . n 
C 1 381 GLN 381 381 381 GLN GLN C . n 
C 1 382 TRP 382 382 382 TRP TRP C . n 
C 1 383 HIS 383 383 383 HIS HIS C . n 
C 1 384 TYR 384 384 384 TYR TYR C . n 
C 1 385 GLY 385 385 385 GLY GLY C . n 
C 1 386 VAL 386 386 386 VAL VAL C . n 
C 1 387 VAL 387 387 387 VAL VAL C . n 
C 1 388 GLU 388 388 388 GLU GLU C . n 
C 1 389 TYR 389 389 389 TYR TYR C . n 
C 1 390 ASP 390 390 390 ASP ASP C . n 
C 1 391 PHE 391 391 391 PHE PHE C . n 
C 1 392 TYR 392 392 392 TYR TYR C . n 
C 1 393 THR 393 393 393 THR THR C . n 
C 1 394 VAL 394 394 394 VAL VAL C . n 
C 1 395 LEU 395 395 395 LEU LEU C . n 
C 1 396 PHE 396 396 396 PHE PHE C . n 
C 1 397 GLY 397 397 397 GLY GLY C . n 
C 1 398 ILE 398 398 398 ILE ILE C . n 
C 1 399 GLY 399 399 399 GLY GLY C . n 
C 1 400 ARG 400 400 400 ARG ARG C . n 
C 1 401 ALA 401 401 401 ALA ALA C . n 
C 1 402 LEU 402 402 402 LEU LEU C . n 
C 1 403 GLY 403 403 403 GLY GLY C . n 
C 1 404 VAL 404 404 404 VAL VAL C . n 
C 1 405 LEU 405 405 405 LEU LEU C . n 
C 1 406 ALA 406 406 406 ALA ALA C . n 
C 1 407 ASN 407 407 407 ASN ASN C . n 
C 1 408 LEU 408 408 408 LEU LEU C . n 
C 1 409 VAL 409 409 409 VAL VAL C . n 
C 1 410 TRP 410 410 410 TRP TRP C . n 
C 1 411 ASP 411 411 411 ASP ASP C . n 
C 1 412 ARG 412 412 412 ARG ARG C . n 
C 1 413 ALA 413 413 413 ALA ALA C . n 
C 1 414 LEU 414 414 414 LEU LEU C . n 
C 1 415 GLY 415 415 415 GLY GLY C . n 
C 1 416 TYR 416 416 416 TYR TYR C . n 
C 1 417 ALA 417 417 417 ALA ALA C . n 
C 1 418 ILE 418 418 418 ILE ILE C . n 
C 1 419 GLU 419 419 419 GLU GLU C . n 
C 1 420 ARG 420 420 420 ARG ARG C . n 
C 1 421 PRO 421 421 421 PRO PRO C . n 
C 1 422 LYS 422 422 422 LYS LYS C . n 
C 1 423 SER 423 423 423 SER SER C . n 
C 1 424 VAL 424 424 424 VAL VAL C . n 
C 1 425 THR 425 425 425 THR THR C . n 
C 1 426 THR 426 426 426 THR THR C . n 
C 1 427 ASP 427 427 427 ASP ASP C . n 
C 1 428 MET 428 428 428 MET MET C . n 
C 1 429 LEU 429 429 429 LEU LEU C . n 
C 1 430 GLU 430 430 430 GLU GLU C . n 
C 1 431 LYS 431 431 431 LYS LYS C . n 
C 1 432 TRP 432 432 432 TRP TRP C . n 
C 1 433 ALA 433 433 433 ALA ALA C . n 
C 1 434 GLY 434 434 434 GLY GLY C . n 
C 1 435 ILE 435 435 435 ILE ILE C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        OAA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   OAA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 OAA 1  501 501 OAA OAA A . 
E 2 OAA 1  501 501 OAA OAA B . 
F 2 OAA 1  501 501 OAA OAA C . 
G 3 HOH 1  601 29  HOH HOH A . 
G 3 HOH 2  602 65  HOH HOH A . 
G 3 HOH 3  603 80  HOH HOH A . 
G 3 HOH 4  604 122 HOH HOH A . 
G 3 HOH 5  605 39  HOH HOH A . 
G 3 HOH 6  606 26  HOH HOH A . 
G 3 HOH 7  607 98  HOH HOH A . 
G 3 HOH 8  608 107 HOH HOH A . 
G 3 HOH 9  609 120 HOH HOH A . 
G 3 HOH 10 610 11  HOH HOH A . 
G 3 HOH 11 611 58  HOH HOH A . 
G 3 HOH 12 612 32  HOH HOH A . 
G 3 HOH 13 613 93  HOH HOH A . 
G 3 HOH 14 614 96  HOH HOH A . 
G 3 HOH 15 615 105 HOH HOH A . 
G 3 HOH 16 616 94  HOH HOH A . 
G 3 HOH 17 617 115 HOH HOH A . 
G 3 HOH 18 618 46  HOH HOH A . 
G 3 HOH 19 619 114 HOH HOH A . 
G 3 HOH 20 620 16  HOH HOH A . 
G 3 HOH 21 621 17  HOH HOH A . 
G 3 HOH 22 622 87  HOH HOH A . 
G 3 HOH 23 623 85  HOH HOH A . 
G 3 HOH 24 624 69  HOH HOH A . 
G 3 HOH 25 625 108 HOH HOH A . 
G 3 HOH 26 626 21  HOH HOH A . 
G 3 HOH 27 627 56  HOH HOH A . 
G 3 HOH 28 628 74  HOH HOH A . 
G 3 HOH 29 629 53  HOH HOH A . 
G 3 HOH 30 630 8   HOH HOH A . 
G 3 HOH 31 631 15  HOH HOH A . 
G 3 HOH 32 632 41  HOH HOH A . 
G 3 HOH 33 633 7   HOH HOH A . 
G 3 HOH 34 634 81  HOH HOH A . 
G 3 HOH 35 635 12  HOH HOH A . 
G 3 HOH 36 636 9   HOH HOH A . 
G 3 HOH 37 637 86  HOH HOH A . 
G 3 HOH 38 638 119 HOH HOH A . 
G 3 HOH 39 639 54  HOH HOH A . 
G 3 HOH 40 640 4   HOH HOH A . 
G 3 HOH 41 641 118 HOH HOH A . 
G 3 HOH 42 642 77  HOH HOH A . 
G 3 HOH 43 643 117 HOH HOH A . 
G 3 HOH 44 644 101 HOH HOH A . 
G 3 HOH 45 645 48  HOH HOH A . 
G 3 HOH 46 646 71  HOH HOH A . 
H 3 HOH 1  601 27  HOH HOH B . 
H 3 HOH 2  602 109 HOH HOH B . 
H 3 HOH 3  603 100 HOH HOH B . 
H 3 HOH 4  604 76  HOH HOH B . 
H 3 HOH 5  605 116 HOH HOH B . 
H 3 HOH 6  606 45  HOH HOH B . 
H 3 HOH 7  607 42  HOH HOH B . 
H 3 HOH 8  608 30  HOH HOH B . 
H 3 HOH 9  609 2   HOH HOH B . 
H 3 HOH 10 610 50  HOH HOH B . 
H 3 HOH 11 611 35  HOH HOH B . 
H 3 HOH 12 612 40  HOH HOH B . 
H 3 HOH 13 613 97  HOH HOH B . 
H 3 HOH 14 614 43  HOH HOH B . 
H 3 HOH 15 615 95  HOH HOH B . 
H 3 HOH 16 616 19  HOH HOH B . 
H 3 HOH 17 617 14  HOH HOH B . 
H 3 HOH 18 618 49  HOH HOH B . 
H 3 HOH 19 619 121 HOH HOH B . 
H 3 HOH 20 620 3   HOH HOH B . 
H 3 HOH 21 621 79  HOH HOH B . 
H 3 HOH 22 622 1   HOH HOH B . 
H 3 HOH 23 623 92  HOH HOH B . 
H 3 HOH 24 625 37  HOH HOH B . 
H 3 HOH 25 626 75  HOH HOH B . 
H 3 HOH 26 627 20  HOH HOH B . 
H 3 HOH 27 628 89  HOH HOH B . 
H 3 HOH 28 630 59  HOH HOH B . 
H 3 HOH 29 631 113 HOH HOH B . 
H 3 HOH 30 632 28  HOH HOH B . 
I 3 HOH 1  601 106 HOH HOH C . 
I 3 HOH 2  602 88  HOH HOH C . 
I 3 HOH 3  603 63  HOH HOH C . 
I 3 HOH 4  604 82  HOH HOH C . 
I 3 HOH 5  605 10  HOH HOH C . 
I 3 HOH 6  606 111 HOH HOH C . 
I 3 HOH 7  607 25  HOH HOH C . 
I 3 HOH 8  608 22  HOH HOH C . 
I 3 HOH 9  609 72  HOH HOH C . 
I 3 HOH 10 610 99  HOH HOH C . 
I 3 HOH 11 611 33  HOH HOH C . 
I 3 HOH 12 612 112 HOH HOH C . 
I 3 HOH 13 613 84  HOH HOH C . 
I 3 HOH 14 614 66  HOH HOH C . 
I 3 HOH 15 615 55  HOH HOH C . 
I 3 HOH 16 616 31  HOH HOH C . 
I 3 HOH 17 617 5   HOH HOH C . 
I 3 HOH 18 618 51  HOH HOH C . 
I 3 HOH 19 619 90  HOH HOH C . 
I 3 HOH 20 620 57  HOH HOH C . 
I 3 HOH 21 621 44  HOH HOH C . 
I 3 HOH 22 622 13  HOH HOH C . 
I 3 HOH 23 623 70  HOH HOH C . 
I 3 HOH 24 624 62  HOH HOH C . 
I 3 HOH 25 625 83  HOH HOH C . 
I 3 HOH 26 626 91  HOH HOH C . 
I 3 HOH 27 627 61  HOH HOH C . 
I 3 HOH 28 628 38  HOH HOH C . 
I 3 HOH 29 629 18  HOH HOH C . 
I 3 HOH 30 630 103 HOH HOH C . 
I 3 HOH 31 631 78  HOH HOH C . 
I 3 HOH 32 632 36  HOH HOH C . 
I 3 HOH 33 633 24  HOH HOH C . 
I 3 HOH 34 634 67  HOH HOH C . 
I 3 HOH 35 635 52  HOH HOH C . 
I 3 HOH 36 636 47  HOH HOH C . 
I 3 HOH 37 637 64  HOH HOH C . 
I 3 HOH 38 638 104 HOH HOH C . 
I 3 HOH 39 639 73  HOH HOH C . 
I 3 HOH 40 640 110 HOH HOH C . 
I 3 HOH 41 641 23  HOH HOH C . 
I 3 HOH 42 642 6   HOH HOH C . 
I 3 HOH 43 643 34  HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 301 ? CG ? A LYS 301 CG 
2  1 Y 1 A LYS 301 ? CD ? A LYS 301 CD 
3  1 Y 1 A LYS 301 ? CE ? A LYS 301 CE 
4  1 Y 1 A LYS 301 ? NZ ? A LYS 301 NZ 
5  1 Y 1 A LYS 367 ? CG ? A LYS 367 CG 
6  1 Y 1 A LYS 367 ? CD ? A LYS 367 CD 
7  1 Y 1 A LYS 367 ? CE ? A LYS 367 CE 
8  1 Y 1 A LYS 367 ? NZ ? A LYS 367 NZ 
9  1 Y 1 B LYS 301 ? CG ? B LYS 301 CG 
10 1 Y 1 B LYS 301 ? CD ? B LYS 301 CD 
11 1 Y 1 B LYS 301 ? CE ? B LYS 301 CE 
12 1 Y 1 B LYS 301 ? NZ ? B LYS 301 NZ 
13 1 Y 1 B LYS 367 ? CG ? B LYS 367 CG 
14 1 Y 1 B LYS 367 ? CD ? B LYS 367 CD 
15 1 Y 1 B LYS 367 ? CE ? B LYS 367 CE 
16 1 Y 1 B LYS 367 ? NZ ? B LYS 367 NZ 
17 1 Y 1 C LYS 301 ? CG ? C LYS 301 CG 
18 1 Y 1 C LYS 301 ? CD ? C LYS 301 CD 
19 1 Y 1 C LYS 301 ? CE ? C LYS 301 CE 
20 1 Y 1 C LYS 301 ? NZ ? C LYS 301 NZ 
21 1 Y 1 C LYS 367 ? CG ? C LYS 367 CG 
22 1 Y 1 C LYS 367 ? CD ? C LYS 367 CD 
23 1 Y 1 C LYS 367 ? CE ? C LYS 367 CE 
24 1 Y 1 C LYS 367 ? NZ ? C LYS 367 NZ 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC ? ? ? 5.8.0352 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? XDS    ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER ? ? ? .        4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   116.07 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8XU1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     155.100 
_cell.length_a_esd                 ? 
_cell.length_b                     111.280 
_cell.length_b_esd                 ? 
_cell.length_c                     99.560 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8XU1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8XU1 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.63 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          53.21 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M KCl, 0.05 M HEPES pH 7.5, 35% v/v Pentaerythritol propoxylate (5/4 PO/OH)' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            289.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-08-18 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRF BEAMLINE BL18U1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL18U1 
_diffrn_source.pdbx_synchrotron_site       SSRF 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8XU1 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.46 
_reflns.d_resolution_low                               45.11 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     54679 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.98 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.3 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          6.7 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.255 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.981 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.182 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.46 
_reflns_shell.d_res_low                                     2.52 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3830 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.5 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.985 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.311 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.1 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.366 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.11 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            -0.05 
_refine.aniso_B[2][2]                            -0.24 
_refine.aniso_B[2][3]                            0.00 
_refine.aniso_B[3][3]                            0.27 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               59.334 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.945 
_refine.correlation_coeff_Fo_to_Fc_free          0.921 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8XU1 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.46 
_refine.ls_d_res_low                             45.11 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     51987 
_refine.ls_number_reflns_R_free                  2662 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.98 
_refine.ls_percent_reflns_R_free                 4.9 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.21335 
_refine.ls_R_factor_R_free                       0.25756 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.21109 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.533 
_refine.pdbx_overall_ESU_R_Free                  0.289 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             14.400 
_refine.overall_SU_ML                            0.281 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.46 
_refine_hist.d_res_low                        45.11 
_refine_hist.number_atoms_solvent             122 
_refine_hist.number_atoms_total               10424 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        10275 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         27 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.008  0.012  10563 ? r_bond_refined_d             ? ? 
'X-RAY DIFFRACTION' ? 0.002  0.016  9786  ? r_bond_other_d               ? ? 
'X-RAY DIFFRACTION' ? 1.470  1.644  14313 ? r_angle_refined_deg          ? ? 
'X-RAY DIFFRACTION' ? 0.459  1.557  22812 ? r_angle_other_deg            ? ? 
'X-RAY DIFFRACTION' ? 6.976  5.000  1299  ? r_dihedral_angle_1_deg       ? ? 
'X-RAY DIFFRACTION' ? 27.462 9.737  57    ? r_dihedral_angle_2_deg       ? ? 
'X-RAY DIFFRACTION' ? 17.772 10.000 1809  ? r_dihedral_angle_3_deg       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_dihedral_angle_4_deg       ? ? 
'X-RAY DIFFRACTION' ? 0.061  0.200  1548  ? r_chiral_restr               ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  11883 ? r_gen_planes_refined         ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  2073  ? r_gen_planes_other           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_refined                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbd_other                  ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_refined              ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_nbtor_other                ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_refined        ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_xyhbond_nbd_other          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_refined          ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_metal_ion_other            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_refined       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_vdw_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_refined     ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_hbond_other       ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_refined ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_symmetry_metal_ion_other   ? ? 
'X-RAY DIFFRACTION' ? 5.214  5.856  5205  ? r_mcbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.212  5.856  5205  ? r_mcbond_other               ? ? 
'X-RAY DIFFRACTION' ? 7.729  8.768  6501  ? r_mcangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 7.729  8.769  6502  ? r_mcangle_other              ? ? 
'X-RAY DIFFRACTION' ? 5.780  6.379  5358  ? r_scbond_it                  ? ? 
'X-RAY DIFFRACTION' ? 5.779  6.379  5358  ? r_scbond_other               ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_scangle_it                 ? ? 
'X-RAY DIFFRACTION' ? 8.946  9.357  7813  ? r_scangle_other              ? ? 
'X-RAY DIFFRACTION' ? 11.477 73.206 12037 ? r_long_range_B_refined       ? ? 
'X-RAY DIFFRACTION' ? 11.477 73.213 12036 ? r_long_range_B_other         ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_rigid_bond_restr           ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_free            ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?     ? r_sphericity_bonded          ? ? 
# 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                       2.460 
_refine_ls_shell.d_res_low                        2.524 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.number_reflns_R_free             215 
_refine_ls_shell.number_reflns_R_work             3830 
_refine_ls_shell.percent_reflns_obs               99.05 
_refine_ls_shell.percent_reflns_R_free            ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.R_factor_obs                     ? 
_refine_ls_shell.R_factor_R_free_error            ? 
_refine_ls_shell.R_factor_R_work                  0.376 
_refine_ls_shell.redundancy_reflns_all            ? 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.wR_factor_all                    ? 
_refine_ls_shell.wR_factor_obs                    ? 
_refine_ls_shell.wR_factor_R_free                 ? 
_refine_ls_shell.wR_factor_R_work                 ? 
_refine_ls_shell.pdbx_R_complete                  ? 
_refine_ls_shell.pdbx_total_number_of_bins_used   20 
_refine_ls_shell.pdbx_phase_error                 ? 
_refine_ls_shell.pdbx_fsc_work                    ? 
_refine_ls_shell.pdbx_fsc_free                    ? 
_refine_ls_shell.R_factor_R_free                  0.405 
# 
_struct.entry_id                     8XU1 
_struct.title                        'DaCS-oxaloacetate complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8XU1 
_struct_keywords.text            'citrate synthase, citrate cleavage, reversible, TRANSFERASE' 
_struct_keywords.pdbx_keywords   TRANSFERASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
I N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A7C6A739_DESAE 
_struct_ref.pdbx_db_accession          A0A7C6A739 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MSFLKEKLAEKIAQHRPRTTKLLKEFGNTKIDEVTISQAIGGMRGIKCLVTDISYLDPEEGIRFRGYTIPEVLEKLPKVP
GAEMPYVEGQFYLLLTGEVPTEKEVKEVVEEFKKRRALPEYVKDTLRAMPRDTHPMTMFSAGILAMQRESKFAAYYNAGK
FNKNTAWEPMYEDAMDLMAKLPSLGAYIYRMKYKGDTHIPSNPDLDLGGDFANMMGIDKPYDDVARLYFILHSDHESGNV
SAHTAHLVASALSDAYYSYSAAMCGLAGPLHGLANQEVLKWIQETMEKLGGKVPTKEELKKFVEETLDSGQVIPGYGHAV
LRKTDPRYTAQREFALKHLPDDPIFQVVSMLFEVVPPILSSLGKVKDPWPNVDAHSGCIQWHYGVVEYDFYTVLFGIGRA
LGVLSNLVWDRALGYAIERPKSVTTDMLEKMAGI
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8XU1 A 1 ? 435 ? A0A7C6A739 1 ? 434 ? 1 435 
2 1 8XU1 B 1 ? 435 ? A0A7C6A739 1 ? 434 ? 1 435 
3 1 8XU1 C 1 ? 435 ? A0A7C6A739 1 ? 434 ? 1 435 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8XU1 ARG A 21  ? UNP A0A7C6A739 LYS 21  variant   21  1  
1 8XU1 VAL A 29  ? UNP A0A7C6A739 THR 29  variant   29  2  
1 8XU1 SER A 48  ? UNP A0A7C6A739 CYS 48  variant   48  3  
1 8XU1 HIS A 90  ? UNP A0A7C6A739 GLN 90  variant   90  4  
1 8XU1 ASP A 98  ? UNP A0A7C6A739 GLU 98  variant   98  5  
1 8XU1 ALA A 109 ? UNP A0A7C6A739 VAL 109 variant   109 6  
1 8XU1 LYS A 127 ? UNP A0A7C6A739 ARG 127 variant   127 7  
1 8XU1 ALA A 140 ? UNP A0A7C6A739 SER 140 variant   140 8  
1 8XU1 PHE A 171 ? UNP A0A7C6A739 TYR 171 variant   171 9  
1 8XU1 SER A 195 ? UNP A0A7C6A739 GLY 195 variant   195 10 
1 8XU1 ALA A 258 ? UNP A0A7C6A739 SER 258 variant   258 11 
1 8XU1 ILE A 286 ? UNP A0A7C6A739 MET 286 variant   286 12 
1 8XU1 ASP A 287 ? UNP A0A7C6A739 GLU 287 variant   287 13 
1 8XU1 LYS A 288 ? UNP A0A7C6A739 ?   ?   insertion 288 14 
1 8XU1 SER A 309 ? UNP A0A7C6A739 ASP 308 variant   309 15 
1 8XU1 VAL A 330 ? UNP A0A7C6A739 THR 329 variant   330 16 
1 8XU1 MET A 340 ? UNP A0A7C6A739 LEU 339 variant   340 17 
1 8XU1 TYR A 353 ? UNP A0A7C6A739 PHE 352 variant   353 18 
1 8XU1 ALA A 406 ? UNP A0A7C6A739 SER 405 variant   406 19 
1 8XU1 TRP A 432 ? UNP A0A7C6A739 MET 431 variant   432 20 
2 8XU1 ARG B 21  ? UNP A0A7C6A739 LYS 21  variant   21  21 
2 8XU1 VAL B 29  ? UNP A0A7C6A739 THR 29  variant   29  22 
2 8XU1 SER B 48  ? UNP A0A7C6A739 CYS 48  variant   48  23 
2 8XU1 HIS B 90  ? UNP A0A7C6A739 GLN 90  variant   90  24 
2 8XU1 ASP B 98  ? UNP A0A7C6A739 GLU 98  variant   98  25 
2 8XU1 ALA B 109 ? UNP A0A7C6A739 VAL 109 variant   109 26 
2 8XU1 LYS B 127 ? UNP A0A7C6A739 ARG 127 variant   127 27 
2 8XU1 ALA B 140 ? UNP A0A7C6A739 SER 140 variant   140 28 
2 8XU1 PHE B 171 ? UNP A0A7C6A739 TYR 171 variant   171 29 
2 8XU1 SER B 195 ? UNP A0A7C6A739 GLY 195 variant   195 30 
2 8XU1 ALA B 258 ? UNP A0A7C6A739 SER 258 variant   258 31 
2 8XU1 ILE B 286 ? UNP A0A7C6A739 MET 286 variant   286 32 
2 8XU1 ASP B 287 ? UNP A0A7C6A739 GLU 287 variant   287 33 
2 8XU1 LYS B 288 ? UNP A0A7C6A739 ?   ?   insertion 288 34 
2 8XU1 SER B 309 ? UNP A0A7C6A739 ASP 308 variant   309 35 
2 8XU1 VAL B 330 ? UNP A0A7C6A739 THR 329 variant   330 36 
2 8XU1 MET B 340 ? UNP A0A7C6A739 LEU 339 variant   340 37 
2 8XU1 TYR B 353 ? UNP A0A7C6A739 PHE 352 variant   353 38 
2 8XU1 ALA B 406 ? UNP A0A7C6A739 SER 405 variant   406 39 
2 8XU1 TRP B 432 ? UNP A0A7C6A739 MET 431 variant   432 40 
3 8XU1 ARG C 21  ? UNP A0A7C6A739 LYS 21  variant   21  41 
3 8XU1 VAL C 29  ? UNP A0A7C6A739 THR 29  variant   29  42 
3 8XU1 SER C 48  ? UNP A0A7C6A739 CYS 48  variant   48  43 
3 8XU1 HIS C 90  ? UNP A0A7C6A739 GLN 90  variant   90  44 
3 8XU1 ASP C 98  ? UNP A0A7C6A739 GLU 98  variant   98  45 
3 8XU1 ALA C 109 ? UNP A0A7C6A739 VAL 109 variant   109 46 
3 8XU1 LYS C 127 ? UNP A0A7C6A739 ARG 127 variant   127 47 
3 8XU1 ALA C 140 ? UNP A0A7C6A739 SER 140 variant   140 48 
3 8XU1 PHE C 171 ? UNP A0A7C6A739 TYR 171 variant   171 49 
3 8XU1 SER C 195 ? UNP A0A7C6A739 GLY 195 variant   195 50 
3 8XU1 ALA C 258 ? UNP A0A7C6A739 SER 258 variant   258 51 
3 8XU1 ILE C 286 ? UNP A0A7C6A739 MET 286 variant   286 52 
3 8XU1 ASP C 287 ? UNP A0A7C6A739 GLU 287 variant   287 53 
3 8XU1 LYS C 288 ? UNP A0A7C6A739 ?   ?   insertion 288 54 
3 8XU1 SER C 309 ? UNP A0A7C6A739 ASP 308 variant   309 55 
3 8XU1 VAL C 330 ? UNP A0A7C6A739 THR 329 variant   330 56 
3 8XU1 MET C 340 ? UNP A0A7C6A739 LEU 339 variant   340 57 
3 8XU1 TYR C 353 ? UNP A0A7C6A739 PHE 352 variant   353 58 
3 8XU1 ALA C 406 ? UNP A0A7C6A739 SER 405 variant   406 59 
3 8XU1 TRP C 432 ? UNP A0A7C6A739 MET 431 variant   432 60 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_and_software_defined_assembly PISA dimeric 2 
2 author_and_software_defined_assembly PISA dimeric 2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 10290 ? 
1 MORE         -65   ? 
1 'SSA (A^2)'  30070 ? 
2 'ABSA (A^2)' 10280 ? 
2 MORE         -64   ? 
2 'SSA (A^2)'  29840 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1   A,B,D,E,G,H 
2 1,2 C,F,I       
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z     1.0000000000  0.0000000000 0.0000000000 0.0000000000   0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000  0.0000000000  
2 'crystal symmetry operation' 2_556 -x,y,-z+1 -1.0000000000 0.0000000000 0.0000000000 -43.7535240257 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 -1.0000000000 89.4305469922 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 2   ? GLY A 27  ? SER A 2   GLY A 27  1 ? 26 
HELX_P HELX_P2  AA2 ILE A 36  ? GLY A 41  ? ILE A 36  GLY A 41  1 ? 6  
HELX_P HELX_P3  AA3 THR A 68  ? LEU A 76  ? THR A 68  LEU A 76  1 ? 9  
HELX_P HELX_P4  AA4 TYR A 86  ? GLY A 97  ? TYR A 86  GLY A 97  1 ? 12 
HELX_P HELX_P5  AA5 THR A 101 ? ARG A 115 ? THR A 101 ARG A 115 1 ? 15 
HELX_P HELX_P6  AA6 PRO A 119 ? MET A 129 ? PRO A 119 MET A 129 1 ? 11 
HELX_P HELX_P7  AA7 HIS A 134 ? MET A 146 ? HIS A 134 MET A 146 1 ? 13 
HELX_P HELX_P8  AA8 GLN A 147 ? GLU A 149 ? GLN A 147 GLU A 149 5 ? 3  
HELX_P HELX_P9  AA9 SER A 150 ? ALA A 158 ? SER A 150 ALA A 158 1 ? 9  
HELX_P HELX_P10 AB1 ALA A 166 ? LYS A 194 ? ALA A 166 LYS A 194 1 ? 29 
HELX_P HELX_P11 AB2 ASP A 206 ? GLY A 216 ? ASP A 206 GLY A 216 1 ? 11 
HELX_P HELX_P12 AB3 PRO A 220 ? HIS A 232 ? PRO A 220 HIS A 232 1 ? 13 
HELX_P HELX_P13 AB4 ASN A 239 ? SER A 250 ? ASN A 239 SER A 250 1 ? 12 
HELX_P HELX_P14 AB5 ASP A 254 ? ALA A 267 ? ASP A 254 ALA A 267 1 ? 14 
HELX_P HELX_P15 AB6 LEU A 273 ? LYS A 288 ? LEU A 273 LYS A 288 1 ? 16 
HELX_P HELX_P16 AB7 THR A 296 ? SER A 309 ? THR A 296 SER A 309 1 ? 14 
HELX_P HELX_P17 AB8 ASP A 326 ? MET A 340 ? ASP A 326 MET A 340 1 ? 15 
HELX_P HELX_P18 AB9 ASP A 343 ? LEU A 363 ? ASP A 343 LEU A 363 1 ? 21 
HELX_P HELX_P19 AC1 VAL A 373 ? TYR A 384 ? VAL A 373 TYR A 384 1 ? 12 
HELX_P HELX_P20 AC2 GLU A 388 ? ASP A 390 ? GLU A 388 ASP A 390 5 ? 3  
HELX_P HELX_P21 AC3 PHE A 391 ? LEU A 414 ? PHE A 391 LEU A 414 1 ? 24 
HELX_P HELX_P22 AC4 THR A 425 ? GLY A 434 ? THR A 425 GLY A 434 1 ? 10 
HELX_P HELX_P23 AC5 PHE B 3   ? GLY B 27  ? PHE B 3   GLY B 27  1 ? 25 
HELX_P HELX_P24 AC6 ILE B 36  ? GLY B 41  ? ILE B 36  GLY B 41  1 ? 6  
HELX_P HELX_P25 AC7 THR B 68  ? LEU B 76  ? THR B 68  LEU B 76  1 ? 9  
HELX_P HELX_P26 AC8 TYR B 86  ? GLY B 97  ? TYR B 86  GLY B 97  1 ? 12 
HELX_P HELX_P27 AC9 THR B 101 ? ARG B 116 ? THR B 101 ARG B 116 1 ? 16 
HELX_P HELX_P28 AD1 PRO B 119 ? MET B 129 ? PRO B 119 MET B 129 1 ? 11 
HELX_P HELX_P29 AD2 HIS B 134 ? MET B 146 ? HIS B 134 MET B 146 1 ? 13 
HELX_P HELX_P30 AD3 GLN B 147 ? GLU B 149 ? GLN B 147 GLU B 149 5 ? 3  
HELX_P HELX_P31 AD4 SER B 150 ? ALA B 158 ? SER B 150 ALA B 158 1 ? 9  
HELX_P HELX_P32 AD5 ALA B 166 ? LYS B 194 ? ALA B 166 LYS B 194 1 ? 29 
HELX_P HELX_P33 AD6 ASP B 206 ? GLY B 216 ? ASP B 206 GLY B 216 1 ? 11 
HELX_P HELX_P34 AD7 PRO B 220 ? HIS B 232 ? PRO B 220 HIS B 232 1 ? 13 
HELX_P HELX_P35 AD8 ASN B 239 ? ALA B 251 ? ASN B 239 ALA B 251 1 ? 13 
HELX_P HELX_P36 AD9 ASP B 254 ? ALA B 267 ? ASP B 254 ALA B 267 1 ? 14 
HELX_P HELX_P37 AE1 LEU B 273 ? LYS B 289 ? LEU B 273 LYS B 289 1 ? 17 
HELX_P HELX_P38 AE2 THR B 296 ? SER B 309 ? THR B 296 SER B 309 1 ? 14 
HELX_P HELX_P39 AE3 ASP B 326 ? MET B 340 ? ASP B 326 MET B 340 1 ? 15 
HELX_P HELX_P40 AE4 ASP B 343 ? LEU B 363 ? ASP B 343 LEU B 363 1 ? 21 
HELX_P HELX_P41 AE5 VAL B 373 ? TYR B 384 ? VAL B 373 TYR B 384 1 ? 12 
HELX_P HELX_P42 AE6 GLU B 388 ? ASP B 390 ? GLU B 388 ASP B 390 5 ? 3  
HELX_P HELX_P43 AE7 PHE B 391 ? LEU B 414 ? PHE B 391 LEU B 414 1 ? 24 
HELX_P HELX_P44 AE8 THR B 425 ? GLY B 434 ? THR B 425 GLY B 434 1 ? 10 
HELX_P HELX_P45 AE9 PHE C 3   ? GLY C 27  ? PHE C 3   GLY C 27  1 ? 25 
HELX_P HELX_P46 AF1 THR C 35  ? GLY C 41  ? THR C 35  GLY C 41  1 ? 7  
HELX_P HELX_P47 AF2 THR C 68  ? LEU C 76  ? THR C 68  LEU C 76  1 ? 9  
HELX_P HELX_P48 AF3 TYR C 86  ? GLY C 97  ? TYR C 86  GLY C 97  1 ? 12 
HELX_P HELX_P49 AF4 THR C 101 ? ARG C 116 ? THR C 101 ARG C 116 1 ? 16 
HELX_P HELX_P50 AF5 PRO C 119 ? MET C 129 ? PRO C 119 MET C 129 1 ? 11 
HELX_P HELX_P51 AF6 HIS C 134 ? MET C 146 ? HIS C 134 MET C 146 1 ? 13 
HELX_P HELX_P52 AF7 GLN C 147 ? GLU C 149 ? GLN C 147 GLU C 149 5 ? 3  
HELX_P HELX_P53 AF8 SER C 150 ? ALA C 158 ? SER C 150 ALA C 158 1 ? 9  
HELX_P HELX_P54 AF9 ALA C 166 ? LYS C 194 ? ALA C 166 LYS C 194 1 ? 29 
HELX_P HELX_P55 AG1 ASP C 206 ? GLY C 216 ? ASP C 206 GLY C 216 1 ? 11 
HELX_P HELX_P56 AG2 PRO C 220 ? HIS C 232 ? PRO C 220 HIS C 232 1 ? 13 
HELX_P HELX_P57 AG3 ASN C 239 ? ALA C 251 ? ASN C 239 ALA C 251 1 ? 13 
HELX_P HELX_P58 AG4 ASP C 254 ? ALA C 267 ? ASP C 254 ALA C 267 1 ? 14 
HELX_P HELX_P59 AG5 LEU C 273 ? LYS C 289 ? LEU C 273 LYS C 289 1 ? 17 
HELX_P HELX_P60 AG6 THR C 296 ? SER C 309 ? THR C 296 SER C 309 1 ? 14 
HELX_P HELX_P61 AG7 ASP C 326 ? MET C 340 ? ASP C 326 MET C 340 1 ? 15 
HELX_P HELX_P62 AG8 ASP C 343 ? LEU C 363 ? ASP C 343 LEU C 363 1 ? 21 
HELX_P HELX_P63 AG9 VAL C 373 ? TYR C 384 ? VAL C 373 TYR C 384 1 ? 12 
HELX_P HELX_P64 AH1 GLU C 388 ? ASP C 390 ? GLU C 388 ASP C 390 5 ? 3  
HELX_P HELX_P65 AH2 PHE C 391 ? LEU C 414 ? PHE C 391 LEU C 414 1 ? 24 
HELX_P HELX_P66 AH3 THR C 425 ? GLY C 434 ? THR C 425 GLY C 434 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 LYS 219 A . ? LYS 219 A PRO 220 A ? PRO 220 A 1 6.55 
2 LYS 219 B . ? LYS 219 B PRO 220 B ? PRO 220 B 1 4.05 
3 LYS 219 C . ? LYS 219 C PRO 220 C ? PRO 220 C 1 5.05 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? parallel      
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS A 30  ? THR A 35  ? LYS A 30  THR A 35  
AA1 2 LYS B 30  ? THR B 35  ? LYS B 30  THR B 35  
AA2 1 LYS A 47  ? VAL A 50  ? LYS A 47  VAL A 50  
AA2 2 LYS B 422 ? VAL B 424 ? LYS B 422 VAL B 424 
AA3 1 SER A 54  ? ASP A 57  ? SER A 54  ASP A 57  
AA3 2 GLY A 61  ? PHE A 64  ? GLY A 61  PHE A 64  
AA4 1 LYS A 422 ? VAL A 424 ? LYS A 422 VAL A 424 
AA4 2 LYS B 47  ? VAL B 50  ? LYS B 47  VAL B 50  
AA5 1 SER B 54  ? ASP B 57  ? SER B 54  ASP B 57  
AA5 2 GLY B 61  ? PHE B 64  ? GLY B 61  PHE B 64  
AA6 1 SER C 54  ? ASP C 57  ? SER C 54  ASP C 57  
AA6 2 GLY C 61  ? PHE C 64  ? GLY C 61  PHE C 64  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ASP A 32  ? N ASP A 32  O VAL B 34  ? O VAL B 34  
AA2 1 2 N LEU A 49  ? N LEU A 49  O VAL B 424 ? O VAL B 424 
AA3 1 2 N ASP A 57  ? N ASP A 57  O GLY A 61  ? O GLY A 61  
AA4 1 2 N VAL A 424 ? N VAL A 424 O LEU B 49  ? O LEU B 49  
AA5 1 2 N ASP B 57  ? N ASP B 57  O GLY B 61  ? O GLY B 61  
AA6 1 2 N ASP C 57  ? N ASP C 57  O GLY C 61  ? O GLY C 61  
# 
_pdbx_entry_details.entry_id                   8XU1 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 26  ? ? -141.97 22.25   
2  1 GLU A 59  ? ? -106.31 -61.93  
3  1 HIS A 235 ? ? -156.06 63.08   
4  1 GLU A 236 ? ? 40.43   -177.91 
5  1 HIS A 271 ? ? -126.01 -65.62  
6  1 LYS A 288 ? ? -91.47  -66.21  
7  1 VAL A 321 ? ? -136.23 -60.53  
8  1 MET A 340 ? ? -157.09 57.71   
9  1 LYS A 365 ? ? -102.96 -63.59  
10 1 PRO A 369 ? ? -83.46  35.42   
11 1 PHE B 26  ? ? -141.14 22.81   
12 1 GLU B 59  ? ? -106.74 -63.32  
13 1 HIS B 235 ? ? -156.93 63.08   
14 1 GLU B 236 ? ? 42.09   -178.25 
15 1 HIS B 271 ? ? -128.61 -65.35  
16 1 LYS B 288 ? ? -93.09  -63.11  
17 1 VAL B 321 ? ? -138.81 -59.11  
18 1 MET B 340 ? ? -156.05 57.85   
19 1 LYS B 365 ? ? -101.88 -62.62  
20 1 PRO B 369 ? ? -83.10  35.77   
21 1 PHE C 26  ? ? -141.36 22.78   
22 1 PRO C 58  ? ? -49.31  -20.00  
23 1 GLU C 59  ? ? -108.16 -63.55  
24 1 HIS C 235 ? ? -156.12 59.99   
25 1 GLU C 236 ? ? 67.11   171.40  
26 1 HIS C 271 ? ? -125.23 -66.06  
27 1 LYS C 288 ? ? -90.01  -65.08  
28 1 VAL C 321 ? ? -137.01 -57.89  
29 1 MET C 340 ? ? -157.28 57.29   
30 1 LYS C 365 ? ? -104.28 -62.31  
31 1 PRO C 369 ? ? -83.35  35.49   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1  1 ARG A 16  ? ? 0.269 'SIDE CHAIN' 
2  1 ARG A 44  ? ? 0.157 'SIDE CHAIN' 
3  1 ARG A 63  ? ? 0.223 'SIDE CHAIN' 
4  1 ARG A 115 ? ? 0.103 'SIDE CHAIN' 
5  1 ARG A 116 ? ? 0.155 'SIDE CHAIN' 
6  1 ARG A 190 ? ? 0.080 'SIDE CHAIN' 
7  1 ARG A 323 ? ? 0.131 'SIDE CHAIN' 
8  1 ARG A 333 ? ? 0.207 'SIDE CHAIN' 
9  1 ARG B 16  ? ? 0.271 'SIDE CHAIN' 
10 1 ARG B 21  ? ? 0.093 'SIDE CHAIN' 
11 1 ARG B 44  ? ? 0.155 'SIDE CHAIN' 
12 1 ARG B 63  ? ? 0.223 'SIDE CHAIN' 
13 1 ARG B 115 ? ? 0.101 'SIDE CHAIN' 
14 1 ARG B 116 ? ? 0.142 'SIDE CHAIN' 
15 1 ARG B 190 ? ? 0.077 'SIDE CHAIN' 
16 1 ARG B 323 ? ? 0.135 'SIDE CHAIN' 
17 1 ARG B 333 ? ? 0.207 'SIDE CHAIN' 
18 1 ARG C 16  ? ? 0.258 'SIDE CHAIN' 
19 1 ARG C 21  ? ? 0.162 'SIDE CHAIN' 
20 1 ARG C 44  ? ? 0.157 'SIDE CHAIN' 
21 1 ARG C 63  ? ? 0.208 'SIDE CHAIN' 
22 1 ARG C 115 ? ? 0.097 'SIDE CHAIN' 
23 1 ARG C 116 ? ? 0.143 'SIDE CHAIN' 
24 1 ARG C 323 ? ? 0.142 'SIDE CHAIN' 
25 1 ARG C 333 ? ? 0.211 'SIDE CHAIN' 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A MET 1 ? A MET 1 
2 1 Y 1 B MET 1 ? B MET 1 
3 1 Y 1 C MET 1 ? C MET 1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
OAA O1   O N N 250 
OAA O2   O N N 251 
OAA O4   O N N 252 
OAA O5   O N N 253 
OAA O3   O N N 254 
OAA C1   C N N 255 
OAA C2   C N N 256 
OAA C3   C N N 257 
OAA C4   C N N 258 
OAA HO5  H N N 259 
OAA H21  H N N 260 
OAA H22  H N N 261 
PHE N    N N N 262 
PHE CA   C N S 263 
PHE C    C N N 264 
PHE O    O N N 265 
PHE CB   C N N 266 
PHE CG   C Y N 267 
PHE CD1  C Y N 268 
PHE CD2  C Y N 269 
PHE CE1  C Y N 270 
PHE CE2  C Y N 271 
PHE CZ   C Y N 272 
PHE OXT  O N N 273 
PHE H    H N N 274 
PHE H2   H N N 275 
PHE HA   H N N 276 
PHE HB2  H N N 277 
PHE HB3  H N N 278 
PHE HD1  H N N 279 
PHE HD2  H N N 280 
PHE HE1  H N N 281 
PHE HE2  H N N 282 
PHE HZ   H N N 283 
PHE HXT  H N N 284 
PRO N    N N N 285 
PRO CA   C N S 286 
PRO C    C N N 287 
PRO O    O N N 288 
PRO CB   C N N 289 
PRO CG   C N N 290 
PRO CD   C N N 291 
PRO OXT  O N N 292 
PRO H    H N N 293 
PRO HA   H N N 294 
PRO HB2  H N N 295 
PRO HB3  H N N 296 
PRO HG2  H N N 297 
PRO HG3  H N N 298 
PRO HD2  H N N 299 
PRO HD3  H N N 300 
PRO HXT  H N N 301 
SER N    N N N 302 
SER CA   C N S 303 
SER C    C N N 304 
SER O    O N N 305 
SER CB   C N N 306 
SER OG   O N N 307 
SER OXT  O N N 308 
SER H    H N N 309 
SER H2   H N N 310 
SER HA   H N N 311 
SER HB2  H N N 312 
SER HB3  H N N 313 
SER HG   H N N 314 
SER HXT  H N N 315 
THR N    N N N 316 
THR CA   C N S 317 
THR C    C N N 318 
THR O    O N N 319 
THR CB   C N R 320 
THR OG1  O N N 321 
THR CG2  C N N 322 
THR OXT  O N N 323 
THR H    H N N 324 
THR H2   H N N 325 
THR HA   H N N 326 
THR HB   H N N 327 
THR HG1  H N N 328 
THR HG21 H N N 329 
THR HG22 H N N 330 
THR HG23 H N N 331 
THR HXT  H N N 332 
TRP N    N N N 333 
TRP CA   C N S 334 
TRP C    C N N 335 
TRP O    O N N 336 
TRP CB   C N N 337 
TRP CG   C Y N 338 
TRP CD1  C Y N 339 
TRP CD2  C Y N 340 
TRP NE1  N Y N 341 
TRP CE2  C Y N 342 
TRP CE3  C Y N 343 
TRP CZ2  C Y N 344 
TRP CZ3  C Y N 345 
TRP CH2  C Y N 346 
TRP OXT  O N N 347 
TRP H    H N N 348 
TRP H2   H N N 349 
TRP HA   H N N 350 
TRP HB2  H N N 351 
TRP HB3  H N N 352 
TRP HD1  H N N 353 
TRP HE1  H N N 354 
TRP HE3  H N N 355 
TRP HZ2  H N N 356 
TRP HZ3  H N N 357 
TRP HH2  H N N 358 
TRP HXT  H N N 359 
TYR N    N N N 360 
TYR CA   C N S 361 
TYR C    C N N 362 
TYR O    O N N 363 
TYR CB   C N N 364 
TYR CG   C Y N 365 
TYR CD1  C Y N 366 
TYR CD2  C Y N 367 
TYR CE1  C Y N 368 
TYR CE2  C Y N 369 
TYR CZ   C Y N 370 
TYR OH   O N N 371 
TYR OXT  O N N 372 
TYR H    H N N 373 
TYR H2   H N N 374 
TYR HA   H N N 375 
TYR HB2  H N N 376 
TYR HB3  H N N 377 
TYR HD1  H N N 378 
TYR HD2  H N N 379 
TYR HE1  H N N 380 
TYR HE2  H N N 381 
TYR HH   H N N 382 
TYR HXT  H N N 383 
VAL N    N N N 384 
VAL CA   C N S 385 
VAL C    C N N 386 
VAL O    O N N 387 
VAL CB   C N N 388 
VAL CG1  C N N 389 
VAL CG2  C N N 390 
VAL OXT  O N N 391 
VAL H    H N N 392 
VAL H2   H N N 393 
VAL HA   H N N 394 
VAL HB   H N N 395 
VAL HG11 H N N 396 
VAL HG12 H N N 397 
VAL HG13 H N N 398 
VAL HG21 H N N 399 
VAL HG22 H N N 400 
VAL HG23 H N N 401 
VAL HXT  H N N 402 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
OAA O1  C1   doub N N 237 
OAA O2  C1   sing N N 238 
OAA O4  C4   doub N N 239 
OAA O5  C4   sing N N 240 
OAA O5  HO5  sing N N 241 
OAA O3  C3   doub N N 242 
OAA C1  C2   sing N N 243 
OAA C2  C3   sing N N 244 
OAA C2  H21  sing N N 245 
OAA C2  H22  sing N N 246 
OAA C3  C4   sing N N 247 
PHE N   CA   sing N N 248 
PHE N   H    sing N N 249 
PHE N   H2   sing N N 250 
PHE CA  C    sing N N 251 
PHE CA  CB   sing N N 252 
PHE CA  HA   sing N N 253 
PHE C   O    doub N N 254 
PHE C   OXT  sing N N 255 
PHE CB  CG   sing N N 256 
PHE CB  HB2  sing N N 257 
PHE CB  HB3  sing N N 258 
PHE CG  CD1  doub Y N 259 
PHE CG  CD2  sing Y N 260 
PHE CD1 CE1  sing Y N 261 
PHE CD1 HD1  sing N N 262 
PHE CD2 CE2  doub Y N 263 
PHE CD2 HD2  sing N N 264 
PHE CE1 CZ   doub Y N 265 
PHE CE1 HE1  sing N N 266 
PHE CE2 CZ   sing Y N 267 
PHE CE2 HE2  sing N N 268 
PHE CZ  HZ   sing N N 269 
PHE OXT HXT  sing N N 270 
PRO N   CA   sing N N 271 
PRO N   CD   sing N N 272 
PRO N   H    sing N N 273 
PRO CA  C    sing N N 274 
PRO CA  CB   sing N N 275 
PRO CA  HA   sing N N 276 
PRO C   O    doub N N 277 
PRO C   OXT  sing N N 278 
PRO CB  CG   sing N N 279 
PRO CB  HB2  sing N N 280 
PRO CB  HB3  sing N N 281 
PRO CG  CD   sing N N 282 
PRO CG  HG2  sing N N 283 
PRO CG  HG3  sing N N 284 
PRO CD  HD2  sing N N 285 
PRO CD  HD3  sing N N 286 
PRO OXT HXT  sing N N 287 
SER N   CA   sing N N 288 
SER N   H    sing N N 289 
SER N   H2   sing N N 290 
SER CA  C    sing N N 291 
SER CA  CB   sing N N 292 
SER CA  HA   sing N N 293 
SER C   O    doub N N 294 
SER C   OXT  sing N N 295 
SER CB  OG   sing N N 296 
SER CB  HB2  sing N N 297 
SER CB  HB3  sing N N 298 
SER OG  HG   sing N N 299 
SER OXT HXT  sing N N 300 
THR N   CA   sing N N 301 
THR N   H    sing N N 302 
THR N   H2   sing N N 303 
THR CA  C    sing N N 304 
THR CA  CB   sing N N 305 
THR CA  HA   sing N N 306 
THR C   O    doub N N 307 
THR C   OXT  sing N N 308 
THR CB  OG1  sing N N 309 
THR CB  CG2  sing N N 310 
THR CB  HB   sing N N 311 
THR OG1 HG1  sing N N 312 
THR CG2 HG21 sing N N 313 
THR CG2 HG22 sing N N 314 
THR CG2 HG23 sing N N 315 
THR OXT HXT  sing N N 316 
TRP N   CA   sing N N 317 
TRP N   H    sing N N 318 
TRP N   H2   sing N N 319 
TRP CA  C    sing N N 320 
TRP CA  CB   sing N N 321 
TRP CA  HA   sing N N 322 
TRP C   O    doub N N 323 
TRP C   OXT  sing N N 324 
TRP CB  CG   sing N N 325 
TRP CB  HB2  sing N N 326 
TRP CB  HB3  sing N N 327 
TRP CG  CD1  doub Y N 328 
TRP CG  CD2  sing Y N 329 
TRP CD1 NE1  sing Y N 330 
TRP CD1 HD1  sing N N 331 
TRP CD2 CE2  doub Y N 332 
TRP CD2 CE3  sing Y N 333 
TRP NE1 CE2  sing Y N 334 
TRP NE1 HE1  sing N N 335 
TRP CE2 CZ2  sing Y N 336 
TRP CE3 CZ3  doub Y N 337 
TRP CE3 HE3  sing N N 338 
TRP CZ2 CH2  doub Y N 339 
TRP CZ2 HZ2  sing N N 340 
TRP CZ3 CH2  sing Y N 341 
TRP CZ3 HZ3  sing N N 342 
TRP CH2 HH2  sing N N 343 
TRP OXT HXT  sing N N 344 
TYR N   CA   sing N N 345 
TYR N   H    sing N N 346 
TYR N   H2   sing N N 347 
TYR CA  C    sing N N 348 
TYR CA  CB   sing N N 349 
TYR CA  HA   sing N N 350 
TYR C   O    doub N N 351 
TYR C   OXT  sing N N 352 
TYR CB  CG   sing N N 353 
TYR CB  HB2  sing N N 354 
TYR CB  HB3  sing N N 355 
TYR CG  CD1  doub Y N 356 
TYR CG  CD2  sing Y N 357 
TYR CD1 CE1  sing Y N 358 
TYR CD1 HD1  sing N N 359 
TYR CD2 CE2  doub Y N 360 
TYR CD2 HD2  sing N N 361 
TYR CE1 CZ   doub Y N 362 
TYR CE1 HE1  sing N N 363 
TYR CE2 CZ   sing Y N 364 
TYR CE2 HE2  sing N N 365 
TYR CZ  OH   sing N N 366 
TYR OH  HH   sing N N 367 
TYR OXT HXT  sing N N 368 
VAL N   CA   sing N N 369 
VAL N   H    sing N N 370 
VAL N   H2   sing N N 371 
VAL CA  C    sing N N 372 
VAL CA  CB   sing N N 373 
VAL CA  HA   sing N N 374 
VAL C   O    doub N N 375 
VAL C   OXT  sing N N 376 
VAL CB  CG1  sing N N 377 
VAL CB  CG2  sing N N 378 
VAL CB  HB   sing N N 379 
VAL CG1 HG11 sing N N 380 
VAL CG1 HG12 sing N N 381 
VAL CG1 HG13 sing N N 382 
VAL CG2 HG21 sing N N 383 
VAL CG2 HG22 sing N N 384 
VAL CG2 HG23 sing N N 385 
VAL OXT HXT  sing N N 386 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8XU1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006447 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003154 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.008986 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011182 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . SER A 1 2   ? -51.177 -44.291 41.216  1.00 79.57  ? 2   SER A N   1 
ATOM   2     C CA  . SER A 1 2   ? -52.399 -43.458 41.050  1.00 84.98  ? 2   SER A CA  1 
ATOM   3     C C   . SER A 1 2   ? -53.384 -44.171 40.125  1.00 84.52  ? 2   SER A C   1 
ATOM   4     O O   . SER A 1 2   ? -53.078 -45.231 39.561  1.00 70.80  ? 2   SER A O   1 
ATOM   5     C CB  . SER A 1 2   ? -52.037 -42.087 40.518  1.00 88.80  ? 2   SER A CB  1 
ATOM   6     O OG  . SER A 1 2   ? -51.177 -42.186 39.383  1.00 78.68  ? 2   SER A OG  1 
ATOM   7     N N   . PHE A 1 3   ? -54.563 -43.562 39.961  1.00 84.95  ? 3   PHE A N   1 
ATOM   8     C CA  . PHE A 1 3   ? -55.498 -44.023 38.953  1.00 93.24  ? 3   PHE A CA  1 
ATOM   9     C C   . PHE A 1 3   ? -54.866 -43.907 37.560  1.00 78.52  ? 3   PHE A C   1 
ATOM   10    O O   . PHE A 1 3   ? -54.966 -44.856 36.779  1.00 73.03  ? 3   PHE A O   1 
ATOM   11    C CB  . PHE A 1 3   ? -56.835 -43.286 39.053  1.00 116.90 ? 3   PHE A CB  1 
ATOM   12    C CG  . PHE A 1 3   ? -57.903 -43.864 38.156  1.00 158.20 ? 3   PHE A CG  1 
ATOM   13    C CD1 . PHE A 1 3   ? -58.272 -45.200 38.269  1.00 171.11 ? 3   PHE A CD1 1 
ATOM   14    C CD2 . PHE A 1 3   ? -58.507 -43.098 37.167  1.00 162.05 ? 3   PHE A CD2 1 
ATOM   15    C CE1 . PHE A 1 3   ? -59.237 -45.749 37.435  1.00 168.87 ? 3   PHE A CE1 1 
ATOM   16    C CE2 . PHE A 1 3   ? -59.474 -43.652 36.336  1.00 164.14 ? 3   PHE A CE2 1 
ATOM   17    C CZ  . PHE A 1 3   ? -59.839 -44.975 36.468  1.00 160.83 ? 3   PHE A CZ  1 
ATOM   18    N N   . LEU A 1 4   ? -54.199 -42.769 37.271  1.00 68.25  ? 4   LEU A N   1 
ATOM   19    C CA  . LEU A 1 4   ? -53.608 -42.471 35.963  1.00 59.11  ? 4   LEU A CA  1 
ATOM   20    C C   . LEU A 1 4   ? -52.581 -43.535 35.553  1.00 51.94  ? 4   LEU A C   1 
ATOM   21    O O   . LEU A 1 4   ? -52.599 -44.024 34.429  1.00 39.05  ? 4   LEU A O   1 
ATOM   22    C CB  . LEU A 1 4   ? -52.959 -41.077 36.000  1.00 58.66  ? 4   LEU A CB  1 
ATOM   23    C CG  . LEU A 1 4   ? -52.211 -40.620 34.737  1.00 59.91  ? 4   LEU A CG  1 
ATOM   24    C CD1 . LEU A 1 4   ? -53.082 -40.724 33.489  1.00 59.63  ? 4   LEU A CD1 1 
ATOM   25    C CD2 . LEU A 1 4   ? -51.713 -39.192 34.877  1.00 57.10  ? 4   LEU A CD2 1 
ATOM   26    N N   . LYS A 1 5   ? -51.695 -43.916 36.475  1.00 49.40  ? 5   LYS A N   1 
ATOM   27    C CA  . LYS A 1 5   ? -50.691 -44.910 36.173  1.00 53.73  ? 5   LYS A CA  1 
ATOM   28    C C   . LYS A 1 5   ? -51.317 -46.283 35.906  1.00 54.83  ? 5   LYS A C   1 
ATOM   29    O O   . LYS A 1 5   ? -50.871 -46.992 35.004  1.00 60.87  ? 5   LYS A O   1 
ATOM   30    C CB  . LYS A 1 5   ? -49.669 -44.932 37.308  1.00 57.27  ? 5   LYS A CB  1 
ATOM   31    C CG  . LYS A 1 5   ? -48.409 -45.719 36.981  1.00 60.67  ? 5   LYS A CG  1 
ATOM   32    C CD  . LYS A 1 5   ? -47.239 -45.308 37.818  1.00 63.02  ? 5   LYS A CD  1 
ATOM   33    C CE  . LYS A 1 5   ? -46.114 -46.320 37.788  1.00 68.56  ? 5   LYS A CE  1 
ATOM   34    N NZ  . LYS A 1 5   ? -44.848 -45.749 38.301  1.00 69.47  ? 5   LYS A NZ  1 
ATOM   35    N N   . GLU A 1 6   ? -52.328 -46.677 36.690  1.00 58.13  ? 6   GLU A N   1 
ATOM   36    C CA  . GLU A 1 6   ? -53.014 -47.944 36.463  1.00 59.75  ? 6   GLU A CA  1 
ATOM   37    C C   . GLU A 1 6   ? -53.752 -47.922 35.126  1.00 54.53  ? 6   GLU A C   1 
ATOM   38    O O   . GLU A 1 6   ? -53.655 -48.882 34.375  1.00 55.41  ? 6   GLU A O   1 
ATOM   39    C CB  . GLU A 1 6   ? -54.022 -48.248 37.569  1.00 73.68  ? 6   GLU A CB  1 
ATOM   40    C CG  . GLU A 1 6   ? -53.417 -48.791 38.857  1.00 87.50  ? 6   GLU A CG  1 
ATOM   41    C CD  . GLU A 1 6   ? -54.400 -48.915 40.016  1.00 98.47  ? 6   GLU A CD  1 
ATOM   42    O OE1 . GLU A 1 6   ? -55.559 -48.459 39.867  1.00 109.65 ? 6   GLU A OE1 1 
ATOM   43    O OE2 . GLU A 1 6   ? -54.018 -49.481 41.068  1.00 97.37  ? 6   GLU A OE2 1 
ATOM   44    N N   . LYS A 1 7   ? -54.488 -46.835 34.852  1.00 49.55  ? 7   LYS A N   1 
ATOM   45    C CA  . LYS A 1 7   ? -55.245 -46.637 33.622  1.00 56.76  ? 7   LYS A CA  1 
ATOM   46    C C   . LYS A 1 7   ? -54.316 -46.727 32.410  1.00 56.45  ? 7   LYS A C   1 
ATOM   47    O O   . LYS A 1 7   ? -54.663 -47.283 31.367  1.00 55.38  ? 7   LYS A O   1 
ATOM   48    C CB  . LYS A 1 7   ? -55.968 -45.283 33.713  1.00 68.93  ? 7   LYS A CB  1 
ATOM   49    C CG  . LYS A 1 7   ? -56.454 -44.617 32.416  1.00 77.42  ? 7   LYS A CG  1 
ATOM   50    C CD  . LYS A 1 7   ? -57.551 -45.347 31.687  1.00 83.80  ? 7   LYS A CD  1 
ATOM   51    C CE  . LYS A 1 7   ? -58.886 -45.355 32.407  1.00 89.61  ? 7   LYS A CE  1 
ATOM   52    N NZ  . LYS A 1 7   ? -59.594 -46.642 32.166  1.00 90.86  ? 7   LYS A NZ  1 
ATOM   53    N N   . LEU A 1 8   ? -53.123 -46.154 32.561  1.00 53.83  ? 8   LEU A N   1 
ATOM   54    C CA  . LEU A 1 8   ? -52.162 -46.066 31.475  1.00 47.17  ? 8   LEU A CA  1 
ATOM   55    C C   . LEU A 1 8   ? -51.532 -47.442 31.285  1.00 42.97  ? 8   LEU A C   1 
ATOM   56    O O   . LEU A 1 8   ? -51.188 -47.809 30.180  1.00 47.67  ? 8   LEU A O   1 
ATOM   57    C CB  . LEU A 1 8   ? -51.162 -44.958 31.839  1.00 45.66  ? 8   LEU A CB  1 
ATOM   58    C CG  . LEU A 1 8   ? -49.907 -44.815 30.984  1.00 49.61  ? 8   LEU A CG  1 
ATOM   59    C CD1 . LEU A 1 8   ? -50.241 -44.377 29.562  1.00 55.00  ? 8   LEU A CD1 1 
ATOM   60    C CD2 . LEU A 1 8   ? -48.956 -43.832 31.653  1.00 53.01  ? 8   LEU A CD2 1 
ATOM   61    N N   . ALA A 1 9   ? -51.424 -48.231 32.352  1.00 41.75  ? 9   ALA A N   1 
ATOM   62    C CA  . ALA A 1 9   ? -50.899 -49.584 32.230  1.00 51.03  ? 9   ALA A CA  1 
ATOM   63    C C   . ALA A 1 9   ? -51.866 -50.460 31.444  1.00 53.59  ? 9   ALA A C   1 
ATOM   64    O O   . ALA A 1 9   ? -51.425 -51.360 30.730  1.00 60.68  ? 9   ALA A O   1 
ATOM   65    C CB  . ALA A 1 9   ? -50.630 -50.166 33.598  1.00 54.29  ? 9   ALA A CB  1 
ATOM   66    N N   . GLU A 1 10  ? -53.172 -50.200 31.602  1.00 55.01  ? 10  GLU A N   1 
ATOM   67    C CA  . GLU A 1 10  ? -54.209 -50.954 30.908  1.00 55.41  ? 10  GLU A CA  1 
ATOM   68    C C   . GLU A 1 10  ? -54.107 -50.697 29.413  1.00 51.74  ? 10  GLU A C   1 
ATOM   69    O O   . GLU A 1 10  ? -54.170 -51.629 28.629  1.00 54.98  ? 10  GLU A O   1 
ATOM   70    C CB  . GLU A 1 10  ? -55.612 -50.549 31.361  1.00 58.91  ? 10  GLU A CB  1 
ATOM   71    C CG  . GLU A 1 10  ? -55.967 -51.053 32.748  1.00 70.90  ? 10  GLU A CG  1 
ATOM   72    C CD  . GLU A 1 10  ? -57.140 -50.380 33.455  1.00 79.45  ? 10  GLU A CD  1 
ATOM   73    O OE1 . GLU A 1 10  ? -57.853 -49.533 32.835  1.00 80.44  ? 10  GLU A OE1 1 
ATOM   74    O OE2 . GLU A 1 10  ? -57.315 -50.677 34.652  1.00 71.88  ? 10  GLU A OE2 1 
ATOM   75    N N   . LYS A 1 11  ? -53.953 -49.419 29.044  1.00 53.85  ? 11  LYS A N   1 
ATOM   76    C CA  . LYS A 1 11  ? -53.877 -49.011 27.647  1.00 54.58  ? 11  LYS A CA  1 
ATOM   77    C C   . LYS A 1 11  ? -52.634 -49.596 26.979  1.00 48.86  ? 11  LYS A C   1 
ATOM   78    O O   . LYS A 1 11  ? -52.637 -49.875 25.790  1.00 45.63  ? 11  LYS A O   1 
ATOM   79    C CB  . LYS A 1 11  ? -53.850 -47.484 27.544  1.00 54.34  ? 11  LYS A CB  1 
ATOM   80    C CG  . LYS A 1 11  ? -55.098 -46.782 28.060  1.00 53.26  ? 11  LYS A CG  1 
ATOM   81    C CD  . LYS A 1 11  ? -56.216 -46.728 27.066  1.00 57.78  ? 11  LYS A CD  1 
ATOM   82    C CE  . LYS A 1 11  ? -57.518 -46.277 27.691  1.00 62.72  ? 11  LYS A CE  1 
ATOM   83    N NZ  . LYS A 1 11  ? -58.382 -45.579 26.707  1.00 64.48  ? 11  LYS A NZ  1 
ATOM   84    N N   . ILE A 1 12  ? -51.561 -49.749 27.753  1.00 49.01  ? 12  ILE A N   1 
ATOM   85    C CA  . ILE A 1 12  ? -50.290 -50.212 27.231  1.00 49.15  ? 12  ILE A CA  1 
ATOM   86    C C   . ILE A 1 12  ? -50.419 -51.688 26.880  1.00 53.20  ? 12  ILE A C   1 
ATOM   87    O O   . ILE A 1 12  ? -49.936 -52.117 25.827  1.00 63.77  ? 12  ILE A O   1 
ATOM   88    C CB  . ILE A 1 12  ? -49.157 -49.930 28.247  1.00 47.97  ? 12  ILE A CB  1 
ATOM   89    C CG1 . ILE A 1 12  ? -48.781 -48.442 28.220  1.00 49.91  ? 12  ILE A CG1 1 
ATOM   90    C CG2 . ILE A 1 12  ? -47.945 -50.841 28.006  1.00 46.79  ? 12  ILE A CG2 1 
ATOM   91    C CD1 . ILE A 1 12  ? -47.892 -47.998 29.365  1.00 49.05  ? 12  ILE A CD1 1 
ATOM   92    N N   . ALA A 1 13  ? -51.080 -52.445 27.767  1.00 54.78  ? 13  ALA A N   1 
ATOM   93    C CA  . ALA A 1 13  ? -51.318 -53.867 27.566  1.00 51.87  ? 13  ALA A CA  1 
ATOM   94    C C   . ALA A 1 13  ? -52.222 -54.102 26.352  1.00 51.43  ? 13  ALA A C   1 
ATOM   95    O O   . ALA A 1 13  ? -52.005 -55.059 25.620  1.00 54.51  ? 13  ALA A O   1 
ATOM   96    C CB  . ALA A 1 13  ? -51.914 -54.459 28.813  1.00 47.02  ? 13  ALA A CB  1 
ATOM   97    N N   . GLN A 1 14  ? -53.225 -53.235 26.143  1.00 50.04  ? 14  GLN A N   1 
ATOM   98    C CA  . GLN A 1 14  ? -54.061 -53.289 24.951  1.00 52.95  ? 14  GLN A CA  1 
ATOM   99    C C   . GLN A 1 14  ? -53.261 -52.983 23.677  1.00 56.05  ? 14  GLN A C   1 
ATOM   100   O O   . GLN A 1 14  ? -53.536 -53.559 22.631  1.00 62.36  ? 14  GLN A O   1 
ATOM   101   C CB  . GLN A 1 14  ? -55.251 -52.338 25.077  1.00 51.78  ? 14  GLN A CB  1 
ATOM   102   C CG  . GLN A 1 14  ? -56.431 -52.951 25.837  1.00 62.43  ? 14  GLN A CG  1 
ATOM   103   C CD  . GLN A 1 14  ? -57.208 -51.917 26.624  1.00 72.68  ? 14  GLN A CD  1 
ATOM   104   O OE1 . GLN A 1 14  ? -57.618 -50.873 26.100  1.00 72.24  ? 14  GLN A OE1 1 
ATOM   105   N NE2 . GLN A 1 14  ? -57.352 -52.174 27.918  1.00 69.55  ? 14  GLN A NE2 1 
ATOM   106   N N   . HIS A 1 15  ? -52.267 -52.088 23.746  1.00 54.90  ? 15  HIS A N   1 
ATOM   107   C CA  . HIS A 1 15  ? -51.639 -51.538 22.552  1.00 50.91  ? 15  HIS A CA  1 
ATOM   108   C C   . HIS A 1 15  ? -50.436 -52.372 22.107  1.00 49.35  ? 15  HIS A C   1 
ATOM   109   O O   . HIS A 1 15  ? -50.099 -52.402 20.922  1.00 54.43  ? 15  HIS A O   1 
ATOM   110   C CB  . HIS A 1 15  ? -51.263 -50.076 22.818  1.00 54.32  ? 15  HIS A CB  1 
ATOM   111   C CG  . HIS A 1 15  ? -50.996 -49.232 21.602  1.00 59.06  ? 15  HIS A CG  1 
ATOM   112   N ND1 . HIS A 1 15  ? -49.968 -49.477 20.717  1.00 51.95  ? 15  HIS A ND1 1 
ATOM   113   C CD2 . HIS A 1 15  ? -51.629 -48.088 21.188  1.00 57.98  ? 15  HIS A CD2 1 
ATOM   114   C CE1 . HIS A 1 15  ? -49.973 -48.529 19.781  1.00 58.41  ? 15  HIS A CE1 1 
ATOM   115   N NE2 . HIS A 1 15  ? -50.996 -47.655 20.054  1.00 59.10  ? 15  HIS A NE2 1 
ATOM   116   N N   . ARG A 1 16  ? -49.777 -53.054 23.047  1.00 44.80  ? 16  ARG A N   1 
ATOM   117   C CA  . ARG A 1 16  ? -48.580 -53.805 22.700  1.00 45.16  ? 16  ARG A CA  1 
ATOM   118   C C   . ARG A 1 16  ? -48.906 -54.866 21.643  1.00 48.61  ? 16  ARG A C   1 
ATOM   119   O O   . ARG A 1 16  ? -48.183 -54.966 20.662  1.00 53.82  ? 16  ARG A O   1 
ATOM   120   C CB  . ARG A 1 16  ? -47.887 -54.379 23.946  1.00 41.76  ? 16  ARG A CB  1 
ATOM   121   C CG  . ARG A 1 16  ? -47.049 -53.363 24.703  1.00 44.68  ? 16  ARG A CG  1 
ATOM   122   C CD  . ARG A 1 16  ? -45.958 -53.901 25.611  1.00 46.30  ? 16  ARG A CD  1 
ATOM   123   N NE  . ARG A 1 16  ? -46.167 -53.595 27.028  1.00 46.33  ? 16  ARG A NE  1 
ATOM   124   C CZ  . ARG A 1 16  ? -45.229 -53.147 27.859  1.00 49.55  ? 16  ARG A CZ  1 
ATOM   125   N NH1 . ARG A 1 16  ? -44.785 -51.914 27.790  1.00 43.22  ? 16  ARG A NH1 1 
ATOM   126   N NH2 . ARG A 1 16  ? -44.780 -53.919 28.831  1.00 59.32  ? 16  ARG A NH2 1 
ATOM   127   N N   . PRO A 1 17  ? -49.982 -55.681 21.767  1.00 53.52  ? 17  PRO A N   1 
ATOM   128   C CA  . PRO A 1 17  ? -50.342 -56.663 20.737  1.00 54.20  ? 17  PRO A CA  1 
ATOM   129   C C   . PRO A 1 17  ? -50.484 -56.104 19.320  1.00 54.67  ? 17  PRO A C   1 
ATOM   130   O O   . PRO A 1 17  ? -49.926 -56.656 18.373  1.00 59.05  ? 17  PRO A O   1 
ATOM   131   C CB  . PRO A 1 17  ? -51.702 -57.187 21.234  1.00 54.01  ? 17  PRO A CB  1 
ATOM   132   C CG  . PRO A 1 17  ? -51.585 -57.089 22.728  1.00 54.09  ? 17  PRO A CG  1 
ATOM   133   C CD  . PRO A 1 17  ? -50.884 -55.759 22.923  1.00 55.21  ? 17  PRO A CD  1 
ATOM   134   N N   . ARG A 1 18  ? -51.206 -54.984 19.188  1.00 58.17  ? 18  ARG A N   1 
ATOM   135   C CA  . ARG A 1 18  ? -51.378 -54.306 17.908  1.00 56.10  ? 18  ARG A CA  1 
ATOM   136   C C   . ARG A 1 18  ? -50.031 -54.037 17.232  1.00 58.29  ? 18  ARG A C   1 
ATOM   137   O O   . ARG A 1 18  ? -49.889 -54.218 16.017  1.00 56.46  ? 18  ARG A O   1 
ATOM   138   C CB  . ARG A 1 18  ? -52.120 -52.991 18.136  1.00 57.53  ? 18  ARG A CB  1 
ATOM   139   C CG  . ARG A 1 18  ? -53.556 -53.160 18.608  1.00 57.17  ? 18  ARG A CG  1 
ATOM   140   C CD  . ARG A 1 18  ? -54.192 -51.817 18.907  1.00 63.47  ? 18  ARG A CD  1 
ATOM   141   N NE  . ARG A 1 18  ? -54.290 -50.948 17.736  1.00 64.09  ? 18  ARG A NE  1 
ATOM   142   C CZ  . ARG A 1 18  ? -54.299 -49.613 17.787  1.00 66.20  ? 18  ARG A CZ  1 
ATOM   143   N NH1 . ARG A 1 18  ? -53.959 -48.980 18.892  1.00 72.42  ? 18  ARG A NH1 1 
ATOM   144   N NH2 . ARG A 1 18  ? -54.632 -48.899 16.729  1.00 60.46  ? 18  ARG A NH2 1 
ATOM   145   N N   . THR A 1 19  ? -49.056 -53.593 18.044  1.00 65.85  ? 19  THR A N   1 
ATOM   146   C CA  . THR A 1 19  ? -47.715 -53.230 17.602  1.00 67.72  ? 19  THR A CA  1 
ATOM   147   C C   . THR A 1 19  ? -46.947 -54.504 17.243  1.00 64.43  ? 19  THR A C   1 
ATOM   148   O O   . THR A 1 19  ? -46.317 -54.560 16.187  1.00 61.99  ? 19  THR A O   1 
ATOM   149   C CB  . THR A 1 19  ? -46.993 -52.349 18.650  1.00 70.19  ? 19  THR A CB  1 
ATOM   150   O OG1 . THR A 1 19  ? -47.631 -51.073 18.826  1.00 57.77  ? 19  THR A OG1 1 
ATOM   151   C CG2 . THR A 1 19  ? -45.540 -52.088 18.297  1.00 67.88  ? 19  THR A CG2 1 
ATOM   152   N N   . THR A 1 20  ? -47.005 -55.519 18.120  1.00 61.87  ? 20  THR A N   1 
ATOM   153   C CA  . THR A 1 20  ? -46.296 -56.780 17.922  1.00 67.93  ? 20  THR A CA  1 
ATOM   154   C C   . THR A 1 20  ? -46.745 -57.466 16.637  1.00 63.75  ? 20  THR A C   1 
ATOM   155   O O   . THR A 1 20  ? -45.952 -58.159 15.997  1.00 66.24  ? 20  THR A O   1 
ATOM   156   C CB  . THR A 1 20  ? -46.540 -57.786 19.060  1.00 71.33  ? 20  THR A CB  1 
ATOM   157   O OG1 . THR A 1 20  ? -46.495 -57.083 20.302  1.00 80.39  ? 20  THR A OG1 1 
ATOM   158   C CG2 . THR A 1 20  ? -45.547 -58.929 19.098  1.00 68.15  ? 20  THR A CG2 1 
ATOM   159   N N   . ARG A 1 21  ? -48.027 -57.287 16.303  1.00 61.90  ? 21  ARG A N   1 
ATOM   160   C CA  . ARG A 1 21  ? -48.632 -57.900 15.132  1.00 73.98  ? 21  ARG A CA  1 
ATOM   161   C C   . ARG A 1 21  ? -48.074 -57.231 13.871  1.00 71.04  ? 21  ARG A C   1 
ATOM   162   O O   . ARG A 1 21  ? -47.566 -57.903 12.972  1.00 68.79  ? 21  ARG A O   1 
ATOM   163   C CB  . ARG A 1 21  ? -50.156 -57.795 15.275  1.00 76.75  ? 21  ARG A CB  1 
ATOM   164   C CG  . ARG A 1 21  ? -50.967 -58.655 14.320  1.00 79.57  ? 21  ARG A CG  1 
ATOM   165   C CD  . ARG A 1 21  ? -52.415 -58.735 14.740  1.00 91.13  ? 21  ARG A CD  1 
ATOM   166   N NE  . ARG A 1 21  ? -53.270 -59.246 13.676  1.00 97.35  ? 21  ARG A NE  1 
ATOM   167   C CZ  . ARG A 1 21  ? -54.427 -58.693 13.299  1.00 100.76 ? 21  ARG A CZ  1 
ATOM   168   N NH1 . ARG A 1 21  ? -54.990 -57.718 13.997  1.00 102.37 ? 21  ARG A NH1 1 
ATOM   169   N NH2 . ARG A 1 21  ? -55.050 -59.135 12.222  1.00 91.27  ? 21  ARG A NH2 1 
ATOM   170   N N   . LEU A 1 22  ? -48.144 -55.894 13.823  1.00 67.56  ? 22  LEU A N   1 
ATOM   171   C CA  . LEU A 1 22  ? -47.618 -55.148 12.694  1.00 60.53  ? 22  LEU A CA  1 
ATOM   172   C C   . LEU A 1 22  ? -46.187 -55.572 12.370  1.00 59.64  ? 22  LEU A C   1 
ATOM   173   O O   . LEU A 1 22  ? -45.819 -55.626 11.203  1.00 59.13  ? 22  LEU A O   1 
ATOM   174   C CB  . LEU A 1 22  ? -47.681 -53.661 13.020  1.00 58.33  ? 22  LEU A CB  1 
ATOM   175   C CG  . LEU A 1 22  ? -49.057 -53.022 12.869  1.00 61.82  ? 22  LEU A CG  1 
ATOM   176   C CD1 . LEU A 1 22  ? -49.032 -51.626 13.450  1.00 72.30  ? 22  LEU A CD1 1 
ATOM   177   C CD2 . LEU A 1 22  ? -49.503 -52.956 11.414  1.00 59.29  ? 22  LEU A CD2 1 
ATOM   178   N N   . LEU A 1 23  ? -45.380 -55.860 13.393  1.00 72.89  ? 23  LEU A N   1 
ATOM   179   C CA  . LEU A 1 23  ? -43.972 -56.154 13.184  1.00 83.72  ? 23  LEU A CA  1 
ATOM   180   C C   . LEU A 1 23  ? -43.788 -57.565 12.645  1.00 79.94  ? 23  LEU A C   1 
ATOM   181   O O   . LEU A 1 23  ? -43.048 -57.755 11.683  1.00 85.69  ? 23  LEU A O   1 
ATOM   182   C CB  . LEU A 1 23  ? -43.194 -56.009 14.499  1.00 88.51  ? 23  LEU A CB  1 
ATOM   183   C CG  . LEU A 1 23  ? -42.643 -54.624 14.835  1.00 81.79  ? 23  LEU A CG  1 
ATOM   184   C CD1 . LEU A 1 23  ? -41.520 -54.754 15.870  1.00 74.72  ? 23  LEU A CD1 1 
ATOM   185   C CD2 . LEU A 1 23  ? -42.171 -53.888 13.581  1.00 78.48  ? 23  LEU A CD2 1 
ATOM   186   N N   . LYS A 1 24  ? -44.421 -58.536 13.311  1.00 79.16  ? 24  LYS A N   1 
ATOM   187   C CA  . LYS A 1 24  ? -44.250 -59.940 12.972  1.00 94.13  ? 24  LYS A CA  1 
ATOM   188   C C   . LYS A 1 24  ? -44.950 -60.282 11.652  1.00 95.08  ? 24  LYS A C   1 
ATOM   189   O O   . LYS A 1 24  ? -44.387 -61.012 10.841  1.00 86.56  ? 24  LYS A O   1 
ATOM   190   C CB  . LYS A 1 24  ? -44.795 -60.853 14.078  1.00 97.05  ? 24  LYS A CB  1 
ATOM   191   C CG  . LYS A 1 24  ? -44.168 -62.239 14.100  1.00 90.81  ? 24  LYS A CG  1 
ATOM   192   C CD  . LYS A 1 24  ? -45.162 -63.372 14.186  1.00 98.58  ? 24  LYS A CD  1 
ATOM   193   C CE  . LYS A 1 24  ? -44.532 -64.702 13.817  1.00 104.11 ? 24  LYS A CE  1 
ATOM   194   N NZ  . LYS A 1 24  ? -45.546 -65.689 13.373  1.00 99.96  ? 24  LYS A NZ  1 
ATOM   195   N N   . GLU A 1 25  ? -46.166 -59.752 11.434  1.00 89.85  ? 25  GLU A N   1 
ATOM   196   C CA  . GLU A 1 25  ? -47.007 -60.167 10.318  1.00 88.54  ? 25  GLU A CA  1 
ATOM   197   C C   . GLU A 1 25  ? -46.940 -59.203 9.127   1.00 79.45  ? 25  GLU A C   1 
ATOM   198   O O   . GLU A 1 25  ? -47.395 -59.568 8.041   1.00 69.35  ? 25  GLU A O   1 
ATOM   199   C CB  . GLU A 1 25  ? -48.473 -60.297 10.754  1.00 91.78  ? 25  GLU A CB  1 
ATOM   200   C CG  . GLU A 1 25  ? -48.833 -61.608 11.442  1.00 95.00  ? 25  GLU A CG  1 
ATOM   201   C CD  . GLU A 1 25  ? -50.311 -61.723 11.800  1.00 107.39 ? 25  GLU A CD  1 
ATOM   202   O OE1 . GLU A 1 25  ? -51.168 -61.571 10.896  1.00 99.86  ? 25  GLU A OE1 1 
ATOM   203   O OE2 . GLU A 1 25  ? -50.617 -61.914 12.998  1.00 107.36 ? 25  GLU A OE2 1 
ATOM   204   N N   . PHE A 1 26  ? -46.443 -57.966 9.296   1.00 71.73  ? 26  PHE A N   1 
ATOM   205   C CA  . PHE A 1 26  ? -46.572 -56.982 8.219   1.00 69.24  ? 26  PHE A CA  1 
ATOM   206   C C   . PHE A 1 26  ? -45.329 -56.094 8.084   1.00 57.82  ? 26  PHE A C   1 
ATOM   207   O O   . PHE A 1 26  ? -45.386 -55.023 7.483   1.00 50.66  ? 26  PHE A O   1 
ATOM   208   C CB  . PHE A 1 26  ? -47.860 -56.173 8.424   1.00 78.58  ? 26  PHE A CB  1 
ATOM   209   C CG  . PHE A 1 26  ? -49.124 -56.999 8.405   1.00 90.55  ? 26  PHE A CG  1 
ATOM   210   C CD1 . PHE A 1 26  ? -49.685 -57.401 7.202   1.00 95.24  ? 26  PHE A CD1 1 
ATOM   211   C CD2 . PHE A 1 26  ? -49.726 -57.423 9.586   1.00 105.80 ? 26  PHE A CD2 1 
ATOM   212   C CE1 . PHE A 1 26  ? -50.842 -58.167 7.177   1.00 95.53  ? 26  PHE A CE1 1 
ATOM   213   C CE2 . PHE A 1 26  ? -50.877 -58.200 9.558   1.00 106.25 ? 26  PHE A CE2 1 
ATOM   214   C CZ  . PHE A 1 26  ? -51.434 -58.568 8.353   1.00 103.07 ? 26  PHE A CZ  1 
ATOM   215   N N   . GLY A 1 27  ? -44.191 -56.587 8.581   1.00 56.66  ? 27  GLY A N   1 
ATOM   216   C CA  . GLY A 1 27  ? -42.953 -55.832 8.635   1.00 58.95  ? 27  GLY A CA  1 
ATOM   217   C C   . GLY A 1 27  ? -42.399 -55.422 7.268   1.00 64.48  ? 27  GLY A C   1 
ATOM   218   O O   . GLY A 1 27  ? -41.660 -54.442 7.221   1.00 71.21  ? 27  GLY A O   1 
ATOM   219   N N   . ASN A 1 28  ? -42.727 -56.140 6.174   1.00 65.15  ? 28  ASN A N   1 
ATOM   220   C CA  . ASN A 1 28  ? -42.128 -55.863 4.866   1.00 63.83  ? 28  ASN A CA  1 
ATOM   221   C C   . ASN A 1 28  ? -43.062 -55.024 3.989   1.00 58.18  ? 28  ASN A C   1 
ATOM   222   O O   . ASN A 1 28  ? -42.716 -54.639 2.875   1.00 55.41  ? 28  ASN A O   1 
ATOM   223   C CB  . ASN A 1 28  ? -41.706 -57.137 4.129   1.00 74.03  ? 28  ASN A CB  1 
ATOM   224   C CG  . ASN A 1 28  ? -40.297 -57.570 4.464   1.00 81.06  ? 28  ASN A CG  1 
ATOM   225   O OD1 . ASN A 1 28  ? -40.028 -57.933 5.604   1.00 87.73  ? 28  ASN A OD1 1 
ATOM   226   N ND2 . ASN A 1 28  ? -39.396 -57.541 3.490   1.00 91.79  ? 28  ASN A ND2 1 
ATOM   227   N N   . VAL A 1 29  ? -44.253 -54.708 4.494   1.00 61.18  ? 29  VAL A N   1 
ATOM   228   C CA  . VAL A 1 29  ? -45.167 -53.876 3.731   1.00 63.29  ? 29  VAL A CA  1 
ATOM   229   C C   . VAL A 1 29  ? -44.521 -52.506 3.534   1.00 64.61  ? 29  VAL A C   1 
ATOM   230   O O   . VAL A 1 29  ? -44.154 -51.849 4.514   1.00 61.85  ? 29  VAL A O   1 
ATOM   231   C CB  . VAL A 1 29  ? -46.529 -53.778 4.441   1.00 66.12  ? 29  VAL A CB  1 
ATOM   232   C CG1 . VAL A 1 29  ? -47.413 -52.690 3.848   1.00 65.99  ? 29  VAL A CG1 1 
ATOM   233   C CG2 . VAL A 1 29  ? -47.234 -55.130 4.445   1.00 64.28  ? 29  VAL A CG2 1 
ATOM   234   N N   . LYS A 1 30  ? -44.399 -52.100 2.261   1.00 57.59  ? 30  LYS A N   1 
ATOM   235   C CA  . LYS A 1 30  ? -43.840 -50.810 1.892   1.00 59.86  ? 30  LYS A CA  1 
ATOM   236   C C   . LYS A 1 30  ? -44.845 -49.713 2.243   1.00 59.92  ? 30  LYS A C   1 
ATOM   237   O O   . LYS A 1 30  ? -46.035 -49.976 2.177   1.00 66.59  ? 30  LYS A O   1 
ATOM   238   C CB  . LYS A 1 30  ? -43.460 -50.808 0.402   1.00 63.63  ? 30  LYS A CB  1 
ATOM   239   C CG  . LYS A 1 30  ? -43.431 -49.426 -0.245  1.00 70.36  ? 30  LYS A CG  1 
ATOM   240   C CD  . LYS A 1 30  ? -43.068 -49.360 -1.725  1.00 73.72  ? 30  LYS A CD  1 
ATOM   241   C CE  . LYS A 1 30  ? -43.807 -48.215 -2.404  1.00 90.57  ? 30  LYS A CE  1 
ATOM   242   N NZ  . LYS A 1 30  ? -42.971 -47.426 -3.349  1.00 100.98 ? 30  LYS A NZ  1 
ATOM   243   N N   . ILE A 1 31  ? -44.369 -48.506 2.625   1.00 63.52  ? 31  ILE A N   1 
ATOM   244   C CA  . ILE A 1 31  ? -45.246 -47.383 2.967   1.00 63.56  ? 31  ILE A CA  1 
ATOM   245   C C   . ILE A 1 31  ? -44.798 -46.081 2.312   1.00 59.62  ? 31  ILE A C   1 
ATOM   246   O O   . ILE A 1 31  ? -45.577 -45.135 2.249   1.00 56.63  ? 31  ILE A O   1 
ATOM   247   C CB  . ILE A 1 31  ? -45.372 -47.160 4.490   1.00 70.34  ? 31  ILE A CB  1 
ATOM   248   C CG1 . ILE A 1 31  ? -44.038 -46.735 5.113   1.00 79.89  ? 31  ILE A CG1 1 
ATOM   249   C CG2 . ILE A 1 31  ? -45.974 -48.379 5.182   1.00 71.37  ? 31  ILE A CG2 1 
ATOM   250   C CD1 . ILE A 1 31  ? -44.110 -46.372 6.589   1.00 82.63  ? 31  ILE A CD1 1 
ATOM   251   N N   . ASP A 1 32  ? -43.535 -45.991 1.903   1.00 66.30  ? 32  ASP A N   1 
ATOM   252   C CA  . ASP A 1 32  ? -43.090 -44.820 1.164   1.00 75.29  ? 32  ASP A CA  1 
ATOM   253   C C   . ASP A 1 32  ? -41.788 -45.155 0.437   1.00 71.18  ? 32  ASP A C   1 
ATOM   254   O O   . ASP A 1 32  ? -41.215 -46.236 0.629   1.00 60.66  ? 32  ASP A O   1 
ATOM   255   C CB  . ASP A 1 32  ? -42.952 -43.595 2.088   1.00 78.05  ? 32  ASP A CB  1 
ATOM   256   C CG  . ASP A 1 32  ? -43.326 -42.263 1.452   1.00 82.99  ? 32  ASP A CG  1 
ATOM   257   O OD1 . ASP A 1 32  ? -43.514 -42.226 0.208   1.00 97.63  ? 32  ASP A OD1 1 
ATOM   258   O OD2 . ASP A 1 32  ? -43.477 -41.276 2.208   1.00 71.68  ? 32  ASP A OD2 1 
ATOM   259   N N   . GLU A 1 33  ? -41.343 -44.207 -0.394  1.00 73.25  ? 33  GLU A N   1 
ATOM   260   C CA  . GLU A 1 33  ? -40.038 -44.281 -1.024  1.00 79.06  ? 33  GLU A CA  1 
ATOM   261   C C   . GLU A 1 33  ? -39.287 -42.959 -0.824  1.00 79.94  ? 33  GLU A C   1 
ATOM   262   O O   . GLU A 1 33  ? -39.884 -41.892 -0.680  1.00 81.53  ? 33  GLU A O   1 
ATOM   263   C CB  . GLU A 1 33  ? -40.216 -44.637 -2.499  1.00 92.79  ? 33  GLU A CB  1 
ATOM   264   C CG  . GLU A 1 33  ? -41.162 -43.700 -3.229  1.00 107.04 ? 33  GLU A CG  1 
ATOM   265   C CD  . GLU A 1 33  ? -40.730 -43.341 -4.641  1.00 121.22 ? 33  GLU A CD  1 
ATOM   266   O OE1 . GLU A 1 33  ? -40.785 -44.234 -5.516  1.00 120.87 ? 33  GLU A OE1 1 
ATOM   267   O OE2 . GLU A 1 33  ? -40.299 -42.177 -4.845  1.00 125.48 ? 33  GLU A OE2 1 
ATOM   268   N N   . VAL A 1 34  ? -37.958 -43.059 -0.834  1.00 76.41  ? 34  VAL A N   1 
ATOM   269   C CA  . VAL A 1 34  ? -37.065 -41.928 -0.654  1.00 72.91  ? 34  VAL A CA  1 
ATOM   270   C C   . VAL A 1 34  ? -36.464 -41.547 -2.009  1.00 69.91  ? 34  VAL A C   1 
ATOM   271   O O   . VAL A 1 34  ? -35.879 -42.387 -2.700  1.00 63.89  ? 34  VAL A O   1 
ATOM   272   C CB  . VAL A 1 34  ? -35.954 -42.264 0.364   1.00 78.36  ? 34  VAL A CB  1 
ATOM   273   C CG1 . VAL A 1 34  ? -35.241 -41.010 0.864   1.00 77.20  ? 34  VAL A CG1 1 
ATOM   274   C CG2 . VAL A 1 34  ? -36.485 -43.077 1.536   1.00 71.97  ? 34  VAL A CG2 1 
ATOM   275   N N   . THR A 1 35  ? -36.621 -40.268 -2.371  1.00 63.71  ? 35  THR A N   1 
ATOM   276   C CA  . THR A 1 35  ? -35.975 -39.694 -3.537  1.00 61.94  ? 35  THR A CA  1 
ATOM   277   C C   . THR A 1 35  ? -34.769 -38.872 -3.079  1.00 67.69  ? 35  THR A C   1 
ATOM   278   O O   . THR A 1 35  ? -34.602 -38.598 -1.888  1.00 63.36  ? 35  THR A O   1 
ATOM   279   C CB  . THR A 1 35  ? -36.961 -38.825 -4.331  1.00 64.59  ? 35  THR A CB  1 
ATOM   280   O OG1 . THR A 1 35  ? -37.071 -37.540 -3.708  1.00 64.19  ? 35  THR A OG1 1 
ATOM   281   C CG2 . THR A 1 35  ? -38.332 -39.456 -4.462  1.00 64.97  ? 35  THR A CG2 1 
ATOM   282   N N   . ILE A 1 36  ? -33.952 -38.448 -4.050  1.00 63.19  ? 36  ILE A N   1 
ATOM   283   C CA  . ILE A 1 36  ? -32.768 -37.638 -3.803  1.00 59.58  ? 36  ILE A CA  1 
ATOM   284   C C   . ILE A 1 36  ? -33.162 -36.292 -3.172  1.00 56.91  ? 36  ILE A C   1 
ATOM   285   O O   . ILE A 1 36  ? -32.614 -35.887 -2.142  1.00 63.57  ? 36  ILE A O   1 
ATOM   286   C CB  . ILE A 1 36  ? -31.968 -37.526 -5.123  1.00 61.81  ? 36  ILE A CB  1 
ATOM   287   C CG1 . ILE A 1 36  ? -31.306 -38.875 -5.446  1.00 55.55  ? 36  ILE A CG1 1 
ATOM   288   C CG2 . ILE A 1 36  ? -30.984 -36.355 -5.099  1.00 61.96  ? 36  ILE A CG2 1 
ATOM   289   C CD1 . ILE A 1 36  ? -30.216 -38.841 -6.493  1.00 58.31  ? 36  ILE A CD1 1 
ATOM   290   N N   . SER A 1 37  ? -34.129 -35.612 -3.791  1.00 57.78  ? 37  SER A N   1 
ATOM   291   C CA  . SER A 1 37  ? -34.780 -34.420 -3.271  1.00 64.58  ? 37  SER A CA  1 
ATOM   292   C C   . SER A 1 37  ? -35.017 -34.497 -1.754  1.00 69.81  ? 37  SER A C   1 
ATOM   293   O O   . SER A 1 37  ? -34.870 -33.507 -1.037  1.00 79.86  ? 37  SER A O   1 
ATOM   294   C CB  . SER A 1 37  ? -36.079 -34.217 -4.033  1.00 68.04  ? 37  SER A CB  1 
ATOM   295   O OG  . SER A 1 37  ? -36.674 -32.958 -3.750  1.00 70.32  ? 37  SER A OG  1 
ATOM   296   N N   . GLN A 1 38  ? -35.412 -35.674 -1.264  1.00 68.30  ? 38  GLN A N   1 
ATOM   297   C CA  . GLN A 1 38  ? -35.862 -35.825 0.110   1.00 71.44  ? 38  GLN A CA  1 
ATOM   298   C C   . GLN A 1 38  ? -34.695 -36.068 1.073   1.00 66.51  ? 38  GLN A C   1 
ATOM   299   O O   . GLN A 1 38  ? -34.754 -35.638 2.222   1.00 63.35  ? 38  GLN A O   1 
ATOM   300   C CB  . GLN A 1 38  ? -36.878 -36.967 0.186   1.00 69.33  ? 38  GLN A CB  1 
ATOM   301   C CG  . GLN A 1 38  ? -38.187 -36.666 -0.530  1.00 64.78  ? 38  GLN A CG  1 
ATOM   302   C CD  . GLN A 1 38  ? -39.122 -37.839 -0.405  1.00 66.81  ? 38  GLN A CD  1 
ATOM   303   O OE1 . GLN A 1 38  ? -38.821 -38.950 -0.835  1.00 64.84  ? 38  GLN A OE1 1 
ATOM   304   N NE2 . GLN A 1 38  ? -40.251 -37.604 0.235   1.00 69.32  ? 38  GLN A NE2 1 
ATOM   305   N N   . ALA A 1 39  ? -33.659 -36.788 0.623   1.00 64.50  ? 39  ALA A N   1 
ATOM   306   C CA  . ALA A 1 39  ? -32.469 -37.029 1.434   1.00 67.04  ? 39  ALA A CA  1 
ATOM   307   C C   . ALA A 1 39  ? -31.667 -35.737 1.644   1.00 67.79  ? 39  ALA A C   1 
ATOM   308   O O   . ALA A 1 39  ? -31.119 -35.514 2.726   1.00 63.77  ? 39  ALA A O   1 
ATOM   309   C CB  . ALA A 1 39  ? -31.609 -38.102 0.794   1.00 61.15  ? 39  ALA A CB  1 
ATOM   310   N N   . ILE A 1 40  ? -31.591 -34.900 0.601   1.00 60.88  ? 40  ILE A N   1 
ATOM   311   C CA  . ILE A 1 40  ? -30.875 -33.638 0.659   1.00 61.00  ? 40  ILE A CA  1 
ATOM   312   C C   . ILE A 1 40  ? -31.727 -32.571 1.351   1.00 64.00  ? 40  ILE A C   1 
ATOM   313   O O   . ILE A 1 40  ? -31.196 -31.616 1.923   1.00 72.01  ? 40  ILE A O   1 
ATOM   314   C CB  . ILE A 1 40  ? -30.466 -33.208 -0.760  1.00 59.99  ? 40  ILE A CB  1 
ATOM   315   C CG1 . ILE A 1 40  ? -29.411 -34.151 -1.344  1.00 62.35  ? 40  ILE A CG1 1 
ATOM   316   C CG2 . ILE A 1 40  ? -29.984 -31.768 -0.759  1.00 63.99  ? 40  ILE A CG2 1 
ATOM   317   C CD1 . ILE A 1 40  ? -29.013 -33.835 -2.778  1.00 61.92  ? 40  ILE A CD1 1 
ATOM   318   N N   . GLY A 1 41  ? -33.051 -32.722 1.281   1.00 55.50  ? 41  GLY A N   1 
ATOM   319   C CA  . GLY A 1 41  ? -33.974 -31.726 1.800   1.00 57.65  ? 41  GLY A CA  1 
ATOM   320   C C   . GLY A 1 41  ? -34.601 -32.113 3.143   1.00 59.67  ? 41  GLY A C   1 
ATOM   321   O O   . GLY A 1 41  ? -35.777 -31.836 3.376   1.00 61.59  ? 41  GLY A O   1 
ATOM   322   N N   . GLY A 1 42  ? -33.813 -32.732 4.028   1.00 55.85  ? 42  GLY A N   1 
ATOM   323   C CA  . GLY A 1 42  ? -34.223 -32.937 5.411   1.00 55.84  ? 42  GLY A CA  1 
ATOM   324   C C   . GLY A 1 42  ? -35.431 -33.863 5.529   1.00 53.08  ? 42  GLY A C   1 
ATOM   325   O O   . GLY A 1 42  ? -36.412 -33.516 6.190   1.00 46.41  ? 42  GLY A O   1 
ATOM   326   N N   . MET A 1 43  ? -35.338 -35.010 4.837   1.00 57.72  ? 43  MET A N   1 
ATOM   327   C CA  . MET A 1 43  ? -36.321 -36.080 4.881   1.00 59.67  ? 43  MET A CA  1 
ATOM   328   C C   . MET A 1 43  ? -37.741 -35.572 4.616   1.00 59.94  ? 43  MET A C   1 
ATOM   329   O O   . MET A 1 43  ? -38.701 -36.205 5.047   1.00 66.09  ? 43  MET A O   1 
ATOM   330   C CB  . MET A 1 43  ? -36.301 -36.728 6.267   1.00 62.63  ? 43  MET A CB  1 
ATOM   331   C CG  . MET A 1 43  ? -35.004 -37.421 6.616   1.00 66.47  ? 43  MET A CG  1 
ATOM   332   S SD  . MET A 1 43  ? -35.006 -37.916 8.382   1.00 82.13  ? 43  MET A SD  1 
ATOM   333   C CE  . MET A 1 43  ? -33.402 -38.708 8.495   1.00 83.13  ? 43  MET A CE  1 
ATOM   334   N N   . ARG A 1 44  ? -37.902 -34.456 3.901   1.00 62.70  ? 44  ARG A N   1 
ATOM   335   C CA  . ARG A 1 44  ? -39.207 -33.814 3.824   1.00 71.01  ? 44  ARG A CA  1 
ATOM   336   C C   . ARG A 1 44  ? -40.191 -34.759 3.147   1.00 71.30  ? 44  ARG A C   1 
ATOM   337   O O   . ARG A 1 44  ? -39.938 -35.217 2.038   1.00 75.63  ? 44  ARG A O   1 
ATOM   338   C CB  . ARG A 1 44  ? -39.143 -32.509 3.028   1.00 75.03  ? 44  ARG A CB  1 
ATOM   339   C CG  . ARG A 1 44  ? -40.409 -31.657 3.020   1.00 75.68  ? 44  ARG A CG  1 
ATOM   340   C CD  . ARG A 1 44  ? -40.089 -30.363 2.271   1.00 98.91  ? 44  ARG A CD  1 
ATOM   341   N NE  . ARG A 1 44  ? -39.391 -30.586 0.984   1.00 115.60 ? 44  ARG A NE  1 
ATOM   342   C CZ  . ARG A 1 44  ? -38.087 -30.373 0.729   1.00 109.65 ? 44  ARG A CZ  1 
ATOM   343   N NH1 . ARG A 1 44  ? -37.440 -29.364 1.297   1.00 97.52  ? 44  ARG A NH1 1 
ATOM   344   N NH2 . ARG A 1 44  ? -37.440 -31.162 -0.123  1.00 93.33  ? 44  ARG A NH2 1 
ATOM   345   N N   . GLY A 1 45  ? -41.288 -35.067 3.849   1.00 77.46  ? 45  GLY A N   1 
ATOM   346   C CA  . GLY A 1 45  ? -42.365 -35.882 3.315   1.00 67.86  ? 45  GLY A CA  1 
ATOM   347   C C   . GLY A 1 45  ? -42.217 -37.372 3.632   1.00 65.26  ? 45  GLY A C   1 
ATOM   348   O O   . GLY A 1 45  ? -43.149 -38.128 3.395   1.00 73.75  ? 45  GLY A O   1 
ATOM   349   N N   . ILE A 1 46  ? -41.063 -37.822 4.145   1.00 55.11  ? 46  ILE A N   1 
ATOM   350   C CA  . ILE A 1 46  ? -40.865 -39.246 4.363   1.00 57.34  ? 46  ILE A CA  1 
ATOM   351   C C   . ILE A 1 46  ? -41.648 -39.688 5.593   1.00 61.89  ? 46  ILE A C   1 
ATOM   352   O O   . ILE A 1 46  ? -41.459 -39.137 6.670   1.00 57.14  ? 46  ILE A O   1 
ATOM   353   C CB  . ILE A 1 46  ? -39.394 -39.648 4.547   1.00 55.09  ? 46  ILE A CB  1 
ATOM   354   C CG1 . ILE A 1 46  ? -38.519 -39.244 3.360   1.00 57.58  ? 46  ILE A CG1 1 
ATOM   355   C CG2 . ILE A 1 46  ? -39.300 -41.138 4.852   1.00 54.32  ? 46  ILE A CG2 1 
ATOM   356   C CD1 . ILE A 1 46  ? -37.043 -39.419 3.641   1.00 61.90  ? 46  ILE A CD1 1 
ATOM   357   N N   . LYS A 1 47  ? -42.453 -40.745 5.411   1.00 63.17  ? 47  LYS A N   1 
ATOM   358   C CA  . LYS A 1 47  ? -43.222 -41.375 6.470   1.00 59.36  ? 47  LYS A CA  1 
ATOM   359   C C   . LYS A 1 47  ? -42.314 -42.380 7.159   1.00 56.53  ? 47  LYS A C   1 
ATOM   360   O O   . LYS A 1 47  ? -42.165 -43.511 6.679   1.00 45.68  ? 47  LYS A O   1 
ATOM   361   C CB  . LYS A 1 47  ? -44.483 -42.029 5.893   1.00 65.21  ? 47  LYS A CB  1 
ATOM   362   C CG  . LYS A 1 47  ? -45.581 -41.041 5.534   1.00 68.78  ? 47  LYS A CG  1 
ATOM   363   C CD  . LYS A 1 47  ? -46.473 -41.448 4.381   1.00 67.50  ? 47  LYS A CD  1 
ATOM   364   C CE  . LYS A 1 47  ? -47.360 -40.286 3.987   1.00 73.98  ? 47  LYS A CE  1 
ATOM   365   N NZ  . LYS A 1 47  ? -48.170 -40.586 2.787   1.00 78.76  ? 47  LYS A NZ  1 
ATOM   366   N N   . SER A 1 48  ? -41.685 -41.912 8.252   1.00 54.81  ? 48  SER A N   1 
ATOM   367   C CA  . SER A 1 48  ? -40.582 -42.621 8.888   1.00 60.09  ? 48  SER A CA  1 
ATOM   368   C C   . SER A 1 48  ? -40.747 -42.722 10.410  1.00 57.09  ? 48  SER A C   1 
ATOM   369   O O   . SER A 1 48  ? -39.946 -43.393 11.077  1.00 56.10  ? 48  SER A O   1 
ATOM   370   C CB  . SER A 1 48  ? -39.258 -41.991 8.493   1.00 64.93  ? 48  SER A CB  1 
ATOM   371   O OG  . SER A 1 48  ? -39.350 -40.576 8.428   1.00 64.20  ? 48  SER A OG  1 
ATOM   372   N N   . LEU A 1 49  ? -41.807 -42.112 10.953  1.00 51.67  ? 49  LEU A N   1 
ATOM   373   C CA  . LEU A 1 49  ? -41.986 -42.019 12.393  1.00 55.26  ? 49  LEU A CA  1 
ATOM   374   C C   . LEU A 1 49  ? -43.383 -42.466 12.788  1.00 55.71  ? 49  LEU A C   1 
ATOM   375   O O   . LEU A 1 49  ? -44.350 -42.136 12.099  1.00 58.44  ? 49  LEU A O   1 
ATOM   376   C CB  . LEU A 1 49  ? -41.792 -40.556 12.797  1.00 63.11  ? 49  LEU A CB  1 
ATOM   377   C CG  . LEU A 1 49  ? -40.349 -40.055 12.797  1.00 65.18  ? 49  LEU A CG  1 
ATOM   378   C CD1 . LEU A 1 49  ? -40.324 -38.547 12.978  1.00 69.04  ? 49  LEU A CD1 1 
ATOM   379   C CD2 . LEU A 1 49  ? -39.520 -40.747 13.878  1.00 61.16  ? 49  LEU A CD2 1 
ATOM   380   N N   . VAL A 1 50  ? -43.480 -43.136 13.943  1.00 58.72  ? 50  VAL A N   1 
ATOM   381   C CA  . VAL A 1 50  ? -44.765 -43.603 14.445  1.00 63.15  ? 50  VAL A CA  1 
ATOM   382   C C   . VAL A 1 50  ? -45.081 -42.933 15.787  1.00 56.23  ? 50  VAL A C   1 
ATOM   383   O O   . VAL A 1 50  ? -44.333 -43.097 16.741  1.00 56.31  ? 50  VAL A O   1 
ATOM   384   C CB  . VAL A 1 50  ? -44.789 -45.143 14.558  1.00 68.93  ? 50  VAL A CB  1 
ATOM   385   C CG1 . VAL A 1 50  ? -46.213 -45.670 14.543  1.00 63.82  ? 50  VAL A CG1 1 
ATOM   386   C CG2 . VAL A 1 50  ? -43.961 -45.802 13.463  1.00 74.50  ? 50  VAL A CG2 1 
ATOM   387   N N   . THR A 1 51  ? -46.213 -42.213 15.843  1.00 55.34  ? 51  THR A N   1 
ATOM   388   C CA  . THR A 1 51  ? -46.730 -41.582 17.054  1.00 66.21  ? 51  THR A CA  1 
ATOM   389   C C   . THR A 1 51  ? -48.248 -41.728 17.095  1.00 59.44  ? 51  THR A C   1 
ATOM   390   O O   . THR A 1 51  ? -48.894 -41.585 16.053  1.00 58.99  ? 51  THR A O   1 
ATOM   391   C CB  . THR A 1 51  ? -46.406 -40.070 17.130  1.00 79.23  ? 51  THR A CB  1 
ATOM   392   O OG1 . THR A 1 51  ? -46.882 -39.452 18.334  1.00 75.76  ? 51  THR A OG1 1 
ATOM   393   C CG2 . THR A 1 51  ? -47.018 -39.277 15.996  1.00 86.23  ? 51  THR A CG2 1 
ATOM   394   N N   . ASP A 1 52  ? -48.807 -41.902 18.309  1.00 57.56  ? 52  ASP A N   1 
ATOM   395   C CA  . ASP A 1 52  ? -50.251 -42.028 18.493  1.00 59.76  ? 52  ASP A CA  1 
ATOM   396   C C   . ASP A 1 52  ? -50.838 -40.819 19.217  1.00 57.98  ? 52  ASP A C   1 
ATOM   397   O O   . ASP A 1 52  ? -52.055 -40.644 19.216  1.00 67.67  ? 52  ASP A O   1 
ATOM   398   C CB  . ASP A 1 52  ? -50.583 -43.379 19.128  1.00 65.43  ? 52  ASP A CB  1 
ATOM   399   C CG  . ASP A 1 52  ? -50.114 -44.524 18.232  1.00 74.28  ? 52  ASP A CG  1 
ATOM   400   O OD1 . ASP A 1 52  ? -50.759 -44.703 17.160  1.00 58.89  ? 52  ASP A OD1 1 
ATOM   401   O OD2 . ASP A 1 52  ? -49.046 -45.176 18.561  1.00 74.92  ? 52  ASP A OD2 1 
ATOM   402   N N   . ILE A 1 53  ? -49.977 -39.921 19.711  1.00 57.66  ? 53  ILE A N   1 
ATOM   403   C CA  . ILE A 1 53  ? -50.434 -38.817 20.539  1.00 49.18  ? 53  ILE A CA  1 
ATOM   404   C C   . ILE A 1 53  ? -51.216 -37.828 19.668  1.00 43.92  ? 53  ILE A C   1 
ATOM   405   O O   . ILE A 1 53  ? -52.228 -37.285 20.091  1.00 36.98  ? 53  ILE A O   1 
ATOM   406   C CB  . ILE A 1 53  ? -49.263 -38.138 21.282  1.00 47.29  ? 53  ILE A CB  1 
ATOM   407   C CG1 . ILE A 1 53  ? -48.358 -39.127 22.018  1.00 51.18  ? 53  ILE A CG1 1 
ATOM   408   C CG2 . ILE A 1 53  ? -49.792 -37.090 22.236  1.00 45.11  ? 53  ILE A CG2 1 
ATOM   409   C CD1 . ILE A 1 53  ? -49.028 -39.810 23.185  1.00 48.26  ? 53  ILE A CD1 1 
ATOM   410   N N   . SER A 1 54  ? -50.709 -37.541 18.466  1.00 43.45  ? 54  SER A N   1 
ATOM   411   C CA  . SER A 1 54  ? -51.364 -36.558 17.619  1.00 46.16  ? 54  SER A CA  1 
ATOM   412   C C   . SER A 1 54  ? -51.055 -36.879 16.163  1.00 42.64  ? 54  SER A C   1 
ATOM   413   O O   . SER A 1 54  ? -50.092 -37.591 15.865  1.00 41.09  ? 54  SER A O   1 
ATOM   414   C CB  . SER A 1 54  ? -51.002 -35.110 17.997  1.00 51.85  ? 54  SER A CB  1 
ATOM   415   O OG  . SER A 1 54  ? -49.663 -34.750 17.636  1.00 51.38  ? 54  SER A OG  1 
ATOM   416   N N   . TYR A 1 55  ? -51.932 -36.388 15.288  1.00 40.91  ? 55  TYR A N   1 
ATOM   417   C CA  . TYR A 1 55  ? -51.737 -36.573 13.865  1.00 55.06  ? 55  TYR A CA  1 
ATOM   418   C C   . TYR A 1 55  ? -52.031 -35.253 13.176  1.00 54.41  ? 55  TYR A C   1 
ATOM   419   O O   . TYR A 1 55  ? -53.039 -34.613 13.477  1.00 46.18  ? 55  TYR A O   1 
ATOM   420   C CB  . TYR A 1 55  ? -52.580 -37.705 13.255  1.00 57.99  ? 55  TYR A CB  1 
ATOM   421   C CG  . TYR A 1 55  ? -52.238 -37.911 11.798  1.00 61.11  ? 55  TYR A CG  1 
ATOM   422   C CD1 . TYR A 1 55  ? -50.970 -38.337 11.428  1.00 62.98  ? 55  TYR A CD1 1 
ATOM   423   C CD2 . TYR A 1 55  ? -53.120 -37.572 10.783  1.00 59.06  ? 55  TYR A CD2 1 
ATOM   424   C CE1 . TYR A 1 55  ? -50.604 -38.473 10.096  1.00 69.02  ? 55  TYR A CE1 1 
ATOM   425   C CE2 . TYR A 1 55  ? -52.768 -37.702 9.445   1.00 62.69  ? 55  TYR A CE2 1 
ATOM   426   C CZ  . TYR A 1 55  ? -51.502 -38.152 9.096   1.00 67.45  ? 55  TYR A CZ  1 
ATOM   427   O OH  . TYR A 1 55  ? -51.079 -38.301 7.790   1.00 69.66  ? 55  TYR A OH  1 
ATOM   428   N N   . LEU A 1 56  ? -51.109 -34.867 12.289  1.00 58.39  ? 56  LEU A N   1 
ATOM   429   C CA  . LEU A 1 56  ? -51.258 -33.668 11.483  1.00 69.72  ? 56  LEU A CA  1 
ATOM   430   C C   . LEU A 1 56  ? -51.676 -34.098 10.081  1.00 62.41  ? 56  LEU A C   1 
ATOM   431   O O   . LEU A 1 56  ? -50.885 -34.697 9.355   1.00 72.40  ? 56  LEU A O   1 
ATOM   432   C CB  . LEU A 1 56  ? -49.931 -32.890 11.491  1.00 72.41  ? 56  LEU A CB  1 
ATOM   433   C CG  . LEU A 1 56  ? -49.856 -31.663 10.577  1.00 70.29  ? 56  LEU A CG  1 
ATOM   434   C CD1 . LEU A 1 56  ? -50.948 -30.662 10.918  1.00 70.28  ? 56  LEU A CD1 1 
ATOM   435   C CD2 . LEU A 1 56  ? -48.480 -31.014 10.657  1.00 73.69  ? 56  LEU A CD2 1 
ATOM   436   N N   . ASP A 1 57  ? -52.948 -33.861 9.761   1.00 66.77  ? 57  ASP A N   1 
ATOM   437   C CA  . ASP A 1 57  ? -53.454 -33.964 8.401   1.00 74.60  ? 57  ASP A CA  1 
ATOM   438   C C   . ASP A 1 57  ? -53.076 -32.659 7.696   1.00 75.08  ? 57  ASP A C   1 
ATOM   439   O O   . ASP A 1 57  ? -53.364 -31.598 8.253   1.00 75.74  ? 57  ASP A O   1 
ATOM   440   C CB  . ASP A 1 57  ? -54.967 -34.237 8.439   1.00 73.98  ? 57  ASP A CB  1 
ATOM   441   C CG  . ASP A 1 57  ? -55.644 -34.241 7.079   1.00 77.61  ? 57  ASP A CG  1 
ATOM   442   O OD1 . ASP A 1 57  ? -55.252 -35.070 6.234   1.00 83.29  ? 57  ASP A OD1 1 
ATOM   443   O OD2 . ASP A 1 57  ? -56.547 -33.400 6.866   1.00 71.61  ? 57  ASP A OD2 1 
ATOM   444   N N   . PRO A 1 58  ? -52.389 -32.657 6.514   1.00 74.32  ? 58  PRO A N   1 
ATOM   445   C CA  . PRO A 1 58  ? -52.131 -31.403 5.777   1.00 81.00  ? 58  PRO A CA  1 
ATOM   446   C C   . PRO A 1 58  ? -53.322 -30.442 5.555   1.00 92.75  ? 58  PRO A C   1 
ATOM   447   O O   . PRO A 1 58  ? -53.115 -29.230 5.406   1.00 82.77  ? 58  PRO A O   1 
ATOM   448   C CB  . PRO A 1 58  ? -51.540 -31.915 4.447   1.00 74.51  ? 58  PRO A CB  1 
ATOM   449   C CG  . PRO A 1 58  ? -50.837 -33.210 4.832   1.00 67.05  ? 58  PRO A CG  1 
ATOM   450   C CD  . PRO A 1 58  ? -51.746 -33.826 5.877   1.00 66.74  ? 58  PRO A CD  1 
ATOM   451   N N   . GLU A 1 59  ? -54.562 -30.964 5.638   1.00 94.08  ? 59  GLU A N   1 
ATOM   452   C CA  . GLU A 1 59  ? -55.777 -30.234 5.294   1.00 92.09  ? 59  GLU A CA  1 
ATOM   453   C C   . GLU A 1 59  ? -56.590 -29.816 6.527   1.00 93.14  ? 59  GLU A C   1 
ATOM   454   O O   . GLU A 1 59  ? -56.799 -28.621 6.727   1.00 93.34  ? 59  GLU A O   1 
ATOM   455   C CB  . GLU A 1 59  ? -56.614 -31.100 4.356   1.00 100.98 ? 59  GLU A CB  1 
ATOM   456   C CG  . GLU A 1 59  ? -55.928 -31.358 3.023   1.00 105.86 ? 59  GLU A CG  1 
ATOM   457   C CD  . GLU A 1 59  ? -56.094 -30.270 1.975   1.00 107.15 ? 59  GLU A CD  1 
ATOM   458   O OE1 . GLU A 1 59  ? -57.255 -29.907 1.665   1.00 97.95  ? 59  GLU A OE1 1 
ATOM   459   O OE2 . GLU A 1 59  ? -55.060 -29.826 1.434   1.00 114.54 ? 59  GLU A OE2 1 
ATOM   460   N N   . GLU A 1 60  ? -57.081 -30.776 7.333   1.00 94.75  ? 60  GLU A N   1 
ATOM   461   C CA  . GLU A 1 60  ? -57.944 -30.469 8.476   1.00 92.92  ? 60  GLU A CA  1 
ATOM   462   C C   . GLU A 1 60  ? -57.153 -29.781 9.591   1.00 80.91  ? 60  GLU A C   1 
ATOM   463   O O   . GLU A 1 60  ? -57.710 -28.970 10.334  1.00 75.04  ? 60  GLU A O   1 
ATOM   464   C CB  . GLU A 1 60  ? -58.615 -31.720 9.070   1.00 97.10  ? 60  GLU A CB  1 
ATOM   465   C CG  . GLU A 1 60  ? -59.335 -32.621 8.071   1.00 105.07 ? 60  GLU A CG  1 
ATOM   466   C CD  . GLU A 1 60  ? -60.190 -31.924 7.021   1.00 120.53 ? 60  GLU A CD  1 
ATOM   467   O OE1 . GLU A 1 60  ? -60.936 -30.979 7.391   1.00 110.79 ? 60  GLU A OE1 1 
ATOM   468   O OE2 . GLU A 1 60  ? -60.130 -32.341 5.831   1.00 133.50 ? 60  GLU A OE2 1 
ATOM   469   N N   . GLY A 1 61  ? -55.872 -30.162 9.708   1.00 73.69  ? 61  GLY A N   1 
ATOM   470   C CA  . GLY A 1 61  ? -54.981 -29.708 10.763  1.00 76.96  ? 61  GLY A CA  1 
ATOM   471   C C   . GLY A 1 61  ? -54.612 -30.809 11.762  1.00 66.65  ? 61  GLY A C   1 
ATOM   472   O O   . GLY A 1 61  ? -54.542 -31.988 11.422  1.00 58.37  ? 61  GLY A O   1 
ATOM   473   N N   . ILE A 1 62  ? -54.362 -30.391 13.008  1.00 62.70  ? 62  ILE A N   1 
ATOM   474   C CA  . ILE A 1 62  ? -53.918 -31.276 14.079  1.00 53.57  ? 62  ILE A CA  1 
ATOM   475   C C   . ILE A 1 62  ? -55.152 -31.898 14.760  1.00 50.83  ? 62  ILE A C   1 
ATOM   476   O O   . ILE A 1 62  ? -56.198 -31.249 14.932  1.00 41.25  ? 62  ILE A O   1 
ATOM   477   C CB  . ILE A 1 62  ? -52.955 -30.524 15.045  1.00 46.33  ? 62  ILE A CB  1 
ATOM   478   C CG1 . ILE A 1 62  ? -52.302 -31.432 16.095  1.00 39.11  ? 62  ILE A CG1 1 
ATOM   479   C CG2 . ILE A 1 62  ? -53.622 -29.323 15.709  1.00 47.01  ? 62  ILE A CG2 1 
ATOM   480   C CD1 . ILE A 1 62  ? -51.280 -32.421 15.535  1.00 41.24  ? 62  ILE A CD1 1 
ATOM   481   N N   . ARG A 1 63  ? -55.018 -33.197 15.083  1.00 46.34  ? 63  ARG A N   1 
ATOM   482   C CA  . ARG A 1 63  ? -55.924 -33.904 15.968  1.00 46.82  ? 63  ARG A CA  1 
ATOM   483   C C   . ARG A 1 63  ? -55.103 -34.421 17.134  1.00 48.14  ? 63  ARG A C   1 
ATOM   484   O O   . ARG A 1 63  ? -54.079 -35.068 16.928  1.00 50.51  ? 63  ARG A O   1 
ATOM   485   C CB  . ARG A 1 63  ? -56.571 -35.122 15.292  1.00 54.07  ? 63  ARG A CB  1 
ATOM   486   C CG  . ARG A 1 63  ? -57.660 -34.798 14.273  1.00 62.16  ? 63  ARG A CG  1 
ATOM   487   C CD  . ARG A 1 63  ? -58.528 -36.004 13.950  1.00 71.16  ? 63  ARG A CD  1 
ATOM   488   N NE  . ARG A 1 63  ? -59.167 -35.878 12.642  1.00 83.93  ? 63  ARG A NE  1 
ATOM   489   C CZ  . ARG A 1 63  ? -60.028 -34.920 12.298  1.00 91.14  ? 63  ARG A CZ  1 
ATOM   490   N NH1 . ARG A 1 63  ? -61.095 -34.706 13.059  1.00 78.15  ? 63  ARG A NH1 1 
ATOM   491   N NH2 . ARG A 1 63  ? -59.839 -34.223 11.174  1.00 92.33  ? 63  ARG A NH2 1 
ATOM   492   N N   . PHE A 1 64  ? -55.586 -34.181 18.351  1.00 50.49  ? 64  PHE A N   1 
ATOM   493   C CA  . PHE A 1 64  ? -55.010 -34.771 19.551  1.00 49.59  ? 64  PHE A CA  1 
ATOM   494   C C   . PHE A 1 64  ? -55.777 -36.032 19.918  1.00 46.93  ? 64  PHE A C   1 
ATOM   495   O O   . PHE A 1 64  ? -56.918 -35.922 20.356  1.00 44.45  ? 64  PHE A O   1 
ATOM   496   C CB  . PHE A 1 64  ? -55.081 -33.767 20.707  1.00 51.16  ? 64  PHE A CB  1 
ATOM   497   C CG  . PHE A 1 64  ? -54.397 -32.459 20.402  1.00 49.40  ? 64  PHE A CG  1 
ATOM   498   C CD1 . PHE A 1 64  ? -53.041 -32.431 20.134  1.00 51.43  ? 64  PHE A CD1 1 
ATOM   499   C CD2 . PHE A 1 64  ? -55.113 -31.279 20.321  1.00 53.64  ? 64  PHE A CD2 1 
ATOM   500   C CE1 . PHE A 1 64  ? -52.410 -31.239 19.832  1.00 55.95  ? 64  PHE A CE1 1 
ATOM   501   C CE2 . PHE A 1 64  ? -54.487 -30.087 20.014  1.00 56.00  ? 64  PHE A CE2 1 
ATOM   502   C CZ  . PHE A 1 64  ? -53.136 -30.067 19.789  1.00 59.00  ? 64  PHE A CZ  1 
ATOM   503   N N   . ARG A 1 65  ? -55.155 -37.209 19.718  1.00 46.00  ? 65  ARG A N   1 
ATOM   504   C CA  . ARG A 1 65  ? -55.772 -38.488 20.051  1.00 42.35  ? 65  ARG A CA  1 
ATOM   505   C C   . ARG A 1 65  ? -57.147 -38.605 19.376  1.00 43.33  ? 65  ARG A C   1 
ATOM   506   O O   . ARG A 1 65  ? -58.108 -39.071 19.993  1.00 45.41  ? 65  ARG A O   1 
ATOM   507   C CB  . ARG A 1 65  ? -55.901 -38.602 21.577  1.00 38.83  ? 65  ARG A CB  1 
ATOM   508   C CG  . ARG A 1 65  ? -54.612 -38.874 22.329  1.00 35.89  ? 65  ARG A CG  1 
ATOM   509   C CD  . ARG A 1 65  ? -54.097 -40.277 22.081  1.00 34.76  ? 65  ARG A CD  1 
ATOM   510   N NE  . ARG A 1 65  ? -53.027 -40.579 23.028  1.00 37.00  ? 65  ARG A NE  1 
ATOM   511   C CZ  . ARG A 1 65  ? -52.379 -41.736 23.098  1.00 41.48  ? 65  ARG A CZ  1 
ATOM   512   N NH1 . ARG A 1 65  ? -52.521 -42.641 22.141  1.00 41.68  ? 65  ARG A NH1 1 
ATOM   513   N NH2 . ARG A 1 65  ? -51.613 -41.991 24.150  1.00 41.46  ? 65  ARG A NH2 1 
ATOM   514   N N   . GLY A 1 66  ? -57.248 -38.129 18.128  1.00 37.91  ? 66  GLY A N   1 
ATOM   515   C CA  . GLY A 1 66  ? -58.467 -38.254 17.354  1.00 37.94  ? 66  GLY A CA  1 
ATOM   516   C C   . GLY A 1 66  ? -59.361 -37.022 17.423  1.00 42.90  ? 66  GLY A C   1 
ATOM   517   O O   . GLY A 1 66  ? -60.199 -36.843 16.551  1.00 56.92  ? 66  GLY A O   1 
ATOM   518   N N   . TYR A 1 67  ? -59.199 -36.158 18.427  1.00 40.43  ? 67  TYR A N   1 
ATOM   519   C CA  . TYR A 1 67  ? -60.086 -35.009 18.554  1.00 43.84  ? 67  TYR A CA  1 
ATOM   520   C C   . TYR A 1 67  ? -59.500 -33.767 17.886  1.00 42.41  ? 67  TYR A C   1 
ATOM   521   O O   . TYR A 1 67  ? -58.319 -33.491 17.999  1.00 45.38  ? 67  TYR A O   1 
ATOM   522   C CB  . TYR A 1 67  ? -60.359 -34.680 20.025  1.00 50.40  ? 67  TYR A CB  1 
ATOM   523   C CG  . TYR A 1 67  ? -60.974 -35.802 20.820  1.00 51.42  ? 67  TYR A CG  1 
ATOM   524   C CD1 . TYR A 1 67  ? -62.342 -35.989 20.850  1.00 56.06  ? 67  TYR A CD1 1 
ATOM   525   C CD2 . TYR A 1 67  ? -60.179 -36.707 21.513  1.00 58.05  ? 67  TYR A CD2 1 
ATOM   526   C CE1 . TYR A 1 67  ? -62.912 -37.008 21.599  1.00 60.83  ? 67  TYR A CE1 1 
ATOM   527   C CE2 . TYR A 1 67  ? -60.728 -37.747 22.244  1.00 59.55  ? 67  TYR A CE2 1 
ATOM   528   C CZ  . TYR A 1 67  ? -62.101 -37.893 22.292  1.00 60.14  ? 67  TYR A CZ  1 
ATOM   529   O OH  . TYR A 1 67  ? -62.620 -38.933 23.014  1.00 60.35  ? 67  TYR A OH  1 
ATOM   530   N N   . THR A 1 68  ? -60.360 -32.988 17.215  1.00 51.42  ? 68  THR A N   1 
ATOM   531   C CA  . THR A 1 68  ? -60.003 -31.669 16.720  1.00 50.45  ? 68  THR A CA  1 
ATOM   532   C C   . THR A 1 68  ? -59.869 -30.713 17.898  1.00 49.36  ? 68  THR A C   1 
ATOM   533   O O   . THR A 1 68  ? -60.306 -30.998 19.010  1.00 54.36  ? 68  THR A O   1 
ATOM   534   C CB  . THR A 1 68  ? -61.023 -31.093 15.715  1.00 50.86  ? 68  THR A CB  1 
ATOM   535   O OG1 . THR A 1 68  ? -62.218 -30.678 16.376  1.00 48.53  ? 68  THR A OG1 1 
ATOM   536   C CG2 . THR A 1 68  ? -61.392 -32.056 14.612  1.00 51.90  ? 68  THR A CG2 1 
ATOM   537   N N   . ILE A 1 69  ? -59.289 -29.553 17.620  1.00 47.59  ? 69  ILE A N   1 
ATOM   538   C CA  . ILE A 1 69  ? -59.065 -28.567 18.654  1.00 52.75  ? 69  ILE A CA  1 
ATOM   539   C C   . ILE A 1 69  ? -60.412 -28.104 19.198  1.00 52.87  ? 69  ILE A C   1 
ATOM   540   O O   . ILE A 1 69  ? -60.620 -28.120 20.413  1.00 56.42  ? 69  ILE A O   1 
ATOM   541   C CB  . ILE A 1 69  ? -58.164 -27.443 18.110  1.00 55.35  ? 69  ILE A CB  1 
ATOM   542   C CG1 . ILE A 1 69  ? -56.705 -27.898 18.125  1.00 62.59  ? 69  ILE A CG1 1 
ATOM   543   C CG2 . ILE A 1 69  ? -58.332 -26.147 18.870  1.00 54.06  ? 69  ILE A CG2 1 
ATOM   544   C CD1 . ILE A 1 69  ? -55.861 -27.196 17.116  1.00 64.99  ? 69  ILE A CD1 1 
ATOM   545   N N   . PRO A 1 70  ? -61.388 -27.713 18.347  1.00 53.50  ? 70  PRO A N   1 
ATOM   546   C CA  . PRO A 1 70  ? -62.652 -27.219 18.894  1.00 51.49  ? 70  PRO A CA  1 
ATOM   547   C C   . PRO A 1 70  ? -63.305 -28.311 19.746  1.00 52.71  ? 70  PRO A C   1 
ATOM   548   O O   . PRO A 1 70  ? -63.960 -27.989 20.738  1.00 54.07  ? 70  PRO A O   1 
ATOM   549   C CB  . PRO A 1 70  ? -63.447 -26.742 17.668  1.00 48.48  ? 70  PRO A CB  1 
ATOM   550   C CG  . PRO A 1 70  ? -62.419 -26.661 16.524  1.00 50.29  ? 70  PRO A CG  1 
ATOM   551   C CD  . PRO A 1 70  ? -61.332 -27.665 16.871  1.00 51.72  ? 70  PRO A CD  1 
ATOM   552   N N   . GLU A 1 71  ? -63.063 -29.593 19.405  1.00 50.21  ? 71  GLU A N   1 
ATOM   553   C CA  . GLU A 1 71  ? -63.584 -30.712 20.186  1.00 59.66  ? 71  GLU A CA  1 
ATOM   554   C C   . GLU A 1 71  ? -62.887 -30.785 21.545  1.00 59.85  ? 71  GLU A C   1 
ATOM   555   O O   . GLU A 1 71  ? -63.533 -30.970 22.574  1.00 57.10  ? 71  GLU A O   1 
ATOM   556   C CB  . GLU A 1 71  ? -63.430 -32.056 19.460  1.00 67.33  ? 71  GLU A CB  1 
ATOM   557   C CG  . GLU A 1 71  ? -64.370 -32.261 18.266  1.00 69.59  ? 71  GLU A CG  1 
ATOM   558   C CD  . GLU A 1 71  ? -64.149 -33.481 17.366  1.00 70.52  ? 71  GLU A CD  1 
ATOM   559   O OE1 . GLU A 1 71  ? -63.333 -34.374 17.704  1.00 69.71  ? 71  GLU A OE1 1 
ATOM   560   O OE2 . GLU A 1 71  ? -64.808 -33.550 16.305  1.00 76.43  ? 71  GLU A OE2 1 
ATOM   561   N N   . VAL A 1 72  ? -61.561 -30.638 21.552  1.00 55.91  ? 72  VAL A N   1 
ATOM   562   C CA  . VAL A 1 72  ? -60.806 -30.739 22.789  1.00 51.83  ? 72  VAL A CA  1 
ATOM   563   C C   . VAL A 1 72  ? -61.227 -29.626 23.748  1.00 47.74  ? 72  VAL A C   1 
ATOM   564   O O   . VAL A 1 72  ? -61.453 -29.868 24.935  1.00 52.82  ? 72  VAL A O   1 
ATOM   565   C CB  . VAL A 1 72  ? -59.296 -30.713 22.493  1.00 55.19  ? 72  VAL A CB  1 
ATOM   566   C CG1 . VAL A 1 72  ? -58.476 -30.472 23.752  1.00 58.10  ? 72  VAL A CG1 1 
ATOM   567   C CG2 . VAL A 1 72  ? -58.848 -31.992 21.800  1.00 50.90  ? 72  VAL A CG2 1 
ATOM   568   N N   . LEU A 1 73  ? -61.348 -28.400 23.243  1.00 47.53  ? 73  LEU A N   1 
ATOM   569   C CA  . LEU A 1 73  ? -61.741 -27.288 24.093  1.00 53.38  ? 73  LEU A CA  1 
ATOM   570   C C   . LEU A 1 73  ? -63.174 -27.473 24.576  1.00 54.80  ? 73  LEU A C   1 
ATOM   571   O O   . LEU A 1 73  ? -63.497 -27.105 25.700  1.00 56.47  ? 73  LEU A O   1 
ATOM   572   C CB  . LEU A 1 73  ? -61.601 -25.987 23.304  1.00 57.95  ? 73  LEU A CB  1 
ATOM   573   C CG  . LEU A 1 73  ? -60.192 -25.652 22.810  1.00 58.63  ? 73  LEU A CG  1 
ATOM   574   C CD1 . LEU A 1 73  ? -60.174 -24.242 22.239  1.00 60.60  ? 73  LEU A CD1 1 
ATOM   575   C CD2 . LEU A 1 73  ? -59.154 -25.798 23.919  1.00 53.12  ? 73  LEU A CD2 1 
ATOM   576   N N   . GLU A 1 74  ? -64.013 -28.035 23.697  1.00 61.44  ? 74  GLU A N   1 
ATOM   577   C CA  . GLU A 1 74  ? -65.397 -28.385 23.995  1.00 62.89  ? 74  GLU A CA  1 
ATOM   578   C C   . GLU A 1 74  ? -65.472 -29.347 25.190  1.00 57.14  ? 74  GLU A C   1 
ATOM   579   O O   . GLU A 1 74  ? -66.159 -29.054 26.162  1.00 52.40  ? 74  GLU A O   1 
ATOM   580   C CB  . GLU A 1 74  ? -66.026 -28.902 22.690  1.00 78.14  ? 74  GLU A CB  1 
ATOM   581   C CG  . GLU A 1 74  ? -67.200 -29.870 22.836  1.00 86.08  ? 74  GLU A CG  1 
ATOM   582   C CD  . GLU A 1 74  ? -68.576 -29.248 22.978  1.00 92.35  ? 74  GLU A CD  1 
ATOM   583   O OE1 . GLU A 1 74  ? -68.709 -28.237 23.710  1.00 92.11  ? 74  GLU A OE1 1 
ATOM   584   O OE2 . GLU A 1 74  ? -69.525 -29.782 22.338  1.00 96.67  ? 74  GLU A OE2 1 
ATOM   585   N N   . LYS A 1 75  ? -64.742 -30.475 25.148  1.00 57.23  ? 75  LYS A N   1 
ATOM   586   C CA  . LYS A 1 75  ? -65.008 -31.615 26.017  1.00 51.97  ? 75  LYS A CA  1 
ATOM   587   C C   . LYS A 1 75  ? -64.166 -31.650 27.288  1.00 46.36  ? 75  LYS A C   1 
ATOM   588   O O   . LYS A 1 75  ? -64.519 -32.355 28.222  1.00 50.76  ? 75  LYS A O   1 
ATOM   589   C CB  . LYS A 1 75  ? -64.697 -32.920 25.284  1.00 58.05  ? 75  LYS A CB  1 
ATOM   590   C CG  . LYS A 1 75  ? -65.493 -33.163 24.013  1.00 63.72  ? 75  LYS A CG  1 
ATOM   591   C CD  . LYS A 1 75  ? -64.992 -34.370 23.244  1.00 78.11  ? 75  LYS A CD  1 
ATOM   592   C CE  . LYS A 1 75  ? -65.575 -34.484 21.853  1.00 85.22  ? 75  LYS A CE  1 
ATOM   593   N NZ  . LYS A 1 75  ? -67.044 -34.323 21.871  1.00 93.21  ? 75  LYS A NZ  1 
ATOM   594   N N   . LEU A 1 76  ? -62.997 -31.006 27.306  1.00 44.42  ? 76  LEU A N   1 
ATOM   595   C CA  . LEU A 1 76  ? -62.143 -31.048 28.489  1.00 43.14  ? 76  LEU A CA  1 
ATOM   596   C C   . LEU A 1 76  ? -62.820 -30.290 29.638  1.00 41.04  ? 76  LEU A C   1 
ATOM   597   O O   . LEU A 1 76  ? -63.395 -29.217 29.427  1.00 49.28  ? 76  LEU A O   1 
ATOM   598   C CB  . LEU A 1 76  ? -60.772 -30.444 28.162  1.00 43.03  ? 76  LEU A CB  1 
ATOM   599   C CG  . LEU A 1 76  ? -59.781 -31.311 27.376  1.00 42.29  ? 76  LEU A CG  1 
ATOM   600   C CD1 . LEU A 1 76  ? -58.537 -30.503 27.065  1.00 41.75  ? 76  LEU A CD1 1 
ATOM   601   C CD2 . LEU A 1 76  ? -59.396 -32.608 28.106  1.00 41.62  ? 76  LEU A CD2 1 
ATOM   602   N N   . PRO A 1 77  ? -62.787 -30.813 30.887  1.00 40.17  ? 77  PRO A N   1 
ATOM   603   C CA  . PRO A 1 77  ? -63.269 -30.079 32.069  1.00 43.00  ? 77  PRO A CA  1 
ATOM   604   C C   . PRO A 1 77  ? -62.668 -28.679 32.244  1.00 48.42  ? 77  PRO A C   1 
ATOM   605   O O   . PRO A 1 77  ? -61.450 -28.510 32.200  1.00 49.55  ? 77  PRO A O   1 
ATOM   606   C CB  . PRO A 1 77  ? -62.805 -30.927 33.270  1.00 42.75  ? 77  PRO A CB  1 
ATOM   607   C CG  . PRO A 1 77  ? -62.628 -32.312 32.701  1.00 42.01  ? 77  PRO A CG  1 
ATOM   608   C CD  . PRO A 1 77  ? -62.234 -32.132 31.241  1.00 40.50  ? 77  PRO A CD  1 
ATOM   609   N N   . LYS A 1 78  ? -63.541 -27.686 32.458  1.00 54.81  ? 78  LYS A N   1 
ATOM   610   C CA  . LYS A 1 78  ? -63.157 -26.288 32.585  1.00 52.12  ? 78  LYS A CA  1 
ATOM   611   C C   . LYS A 1 78  ? -62.763 -25.971 34.026  1.00 54.81  ? 78  LYS A C   1 
ATOM   612   O O   . LYS A 1 78  ? -63.189 -26.652 34.967  1.00 47.38  ? 78  LYS A O   1 
ATOM   613   C CB  . LYS A 1 78  ? -64.325 -25.383 32.189  1.00 57.89  ? 78  LYS A CB  1 
ATOM   614   C CG  . LYS A 1 78  ? -64.973 -25.693 30.847  1.00 63.83  ? 78  LYS A CG  1 
ATOM   615   C CD  . LYS A 1 78  ? -64.239 -25.091 29.674  1.00 71.85  ? 78  LYS A CD  1 
ATOM   616   C CE  . LYS A 1 78  ? -64.714 -25.665 28.351  1.00 72.80  ? 78  LYS A CE  1 
ATOM   617   N NZ  . LYS A 1 78  ? -64.473 -27.127 28.268  1.00 71.18  ? 78  LYS A NZ  1 
ATOM   618   N N   . VAL A 1 79  ? -61.964 -24.903 34.189  1.00 56.51  ? 79  VAL A N   1 
ATOM   619   C CA  . VAL A 1 79  ? -61.591 -24.433 35.512  1.00 55.26  ? 79  VAL A CA  1 
ATOM   620   C C   . VAL A 1 79  ? -62.761 -23.614 36.076  1.00 55.77  ? 79  VAL A C   1 
ATOM   621   O O   . VAL A 1 79  ? -63.308 -22.747 35.381  1.00 49.79  ? 79  VAL A O   1 
ATOM   622   C CB  . VAL A 1 79  ? -60.270 -23.634 35.474  1.00 55.44  ? 79  VAL A CB  1 
ATOM   623   C CG1 . VAL A 1 79  ? -59.860 -23.127 36.861  1.00 54.33  ? 79  VAL A CG1 1 
ATOM   624   C CG2 . VAL A 1 79  ? -59.153 -24.456 34.862  1.00 51.79  ? 79  VAL A CG2 1 
ATOM   625   N N   . PRO A 1 80  ? -63.194 -23.869 37.338  1.00 55.36  ? 80  PRO A N   1 
ATOM   626   C CA  . PRO A 1 80  ? -64.212 -23.035 37.985  1.00 56.04  ? 80  PRO A CA  1 
ATOM   627   C C   . PRO A 1 80  ? -63.802 -21.561 38.040  1.00 55.80  ? 80  PRO A C   1 
ATOM   628   O O   . PRO A 1 80  ? -62.714 -21.232 38.516  1.00 56.26  ? 80  PRO A O   1 
ATOM   629   C CB  . PRO A 1 80  ? -64.351 -23.613 39.411  1.00 57.46  ? 80  PRO A CB  1 
ATOM   630   C CG  . PRO A 1 80  ? -63.696 -24.997 39.360  1.00 58.44  ? 80  PRO A CG  1 
ATOM   631   C CD  . PRO A 1 80  ? -62.711 -24.959 38.208  1.00 56.46  ? 80  PRO A CD  1 
ATOM   632   N N   . GLY A 1 81  ? -64.679 -20.685 37.529  1.00 60.60  ? 81  GLY A N   1 
ATOM   633   C CA  . GLY A 1 81  ? -64.442 -19.249 37.480  1.00 60.20  ? 81  GLY A CA  1 
ATOM   634   C C   . GLY A 1 81  ? -63.918 -18.789 36.118  1.00 63.11  ? 81  GLY A C   1 
ATOM   635   O O   . GLY A 1 81  ? -63.876 -17.590 35.868  1.00 70.77  ? 81  GLY A O   1 
ATOM   636   N N   . ALA A 1 82  ? -63.562 -19.740 35.234  1.00 58.28  ? 82  ALA A N   1 
ATOM   637   C CA  . ALA A 1 82  ? -62.736 -19.467 34.064  1.00 56.97  ? 82  ALA A CA  1 
ATOM   638   C C   . ALA A 1 82  ? -63.228 -20.211 32.818  1.00 57.44  ? 82  ALA A C   1 
ATOM   639   O O   . ALA A 1 82  ? -63.812 -21.288 32.901  1.00 61.64  ? 82  ALA A O   1 
ATOM   640   C CB  . ALA A 1 82  ? -61.314 -19.859 34.382  1.00 58.94  ? 82  ALA A CB  1 
ATOM   641   N N   . GLU A 1 83  ? -62.871 -19.660 31.653  1.00 61.30  ? 83  GLU A N   1 
ATOM   642   C CA  . GLU A 1 83  ? -63.409 -20.043 30.356  1.00 63.92  ? 83  GLU A CA  1 
ATOM   643   C C   . GLU A 1 83  ? -62.694 -21.278 29.782  1.00 60.87  ? 83  GLU A C   1 
ATOM   644   O O   . GLU A 1 83  ? -63.242 -21.989 28.931  1.00 50.04  ? 83  GLU A O   1 
ATOM   645   C CB  . GLU A 1 83  ? -63.304 -18.810 29.453  1.00 77.26  ? 83  GLU A CB  1 
ATOM   646   C CG  . GLU A 1 83  ? -63.648 -19.030 27.984  1.00 90.02  ? 83  GLU A CG  1 
ATOM   647   C CD  . GLU A 1 83  ? -63.324 -17.828 27.109  1.00 103.61 ? 83  GLU A CD  1 
ATOM   648   O OE1 . GLU A 1 83  ? -63.056 -18.026 25.893  1.00 103.84 ? 83  GLU A OE1 1 
ATOM   649   O OE2 . GLU A 1 83  ? -63.355 -16.690 27.644  1.00 108.19 ? 83  GLU A OE2 1 
ATOM   650   N N   . MET A 1 84  ? -61.485 -21.566 30.268  1.00 55.41  ? 84  MET A N   1 
ATOM   651   C CA  . MET A 1 84  ? -60.627 -22.522 29.601  1.00 56.38  ? 84  MET A CA  1 
ATOM   652   C C   . MET A 1 84  ? -60.420 -23.766 30.462  1.00 53.38  ? 84  MET A C   1 
ATOM   653   O O   . MET A 1 84  ? -60.555 -23.715 31.691  1.00 52.81  ? 84  MET A O   1 
ATOM   654   C CB  . MET A 1 84  ? -59.275 -21.879 29.296  1.00 64.09  ? 84  MET A CB  1 
ATOM   655   C CG  . MET A 1 84  ? -59.369 -20.886 28.162  1.00 65.61  ? 84  MET A CG  1 
ATOM   656   S SD  . MET A 1 84  ? -59.724 -21.693 26.597  1.00 62.98  ? 84  MET A SD  1 
ATOM   657   C CE  . MET A 1 84  ? -59.769 -20.267 25.519  1.00 68.15  ? 84  MET A CE  1 
ATOM   658   N N   . PRO A 1 85  ? -60.076 -24.910 29.811  1.00 48.44  ? 85  PRO A N   1 
ATOM   659   C CA  . PRO A 1 85  ? -59.831 -26.179 30.507  1.00 49.82  ? 85  PRO A CA  1 
ATOM   660   C C   . PRO A 1 85  ? -58.568 -26.245 31.362  1.00 45.25  ? 85  PRO A C   1 
ATOM   661   O O   . PRO A 1 85  ? -57.613 -25.526 31.108  1.00 52.38  ? 85  PRO A O   1 
ATOM   662   C CB  . PRO A 1 85  ? -59.632 -27.217 29.385  1.00 50.16  ? 85  PRO A CB  1 
ATOM   663   C CG  . PRO A 1 85  ? -60.111 -26.525 28.112  1.00 48.41  ? 85  PRO A CG  1 
ATOM   664   C CD  . PRO A 1 85  ? -59.927 -25.039 28.349  1.00 45.99  ? 85  PRO A CD  1 
ATOM   665   N N   . TYR A 1 86  ? -58.562 -27.161 32.337  1.00 44.97  ? 86  TYR A N   1 
ATOM   666   C CA  . TYR A 1 86  ? -57.351 -27.546 33.039  1.00 43.23  ? 86  TYR A CA  1 
ATOM   667   C C   . TYR A 1 86  ? -56.344 -28.123 32.055  1.00 44.02  ? 86  TYR A C   1 
ATOM   668   O O   . TYR A 1 86  ? -56.663 -29.078 31.352  1.00 49.64  ? 86  TYR A O   1 
ATOM   669   C CB  . TYR A 1 86  ? -57.606 -28.654 34.048  1.00 41.21  ? 86  TYR A CB  1 
ATOM   670   C CG  . TYR A 1 86  ? -58.391 -28.299 35.279  1.00 46.82  ? 86  TYR A CG  1 
ATOM   671   C CD1 . TYR A 1 86  ? -59.766 -28.184 35.243  1.00 48.75  ? 86  TYR A CD1 1 
ATOM   672   C CD2 . TYR A 1 86  ? -57.760 -28.152 36.505  1.00 54.25  ? 86  TYR A CD2 1 
ATOM   673   C CE1 . TYR A 1 86  ? -60.501 -27.917 36.389  1.00 54.95  ? 86  TYR A CE1 1 
ATOM   674   C CE2 . TYR A 1 86  ? -58.476 -27.910 37.669  1.00 53.96  ? 86  TYR A CE2 1 
ATOM   675   C CZ  . TYR A 1 86  ? -59.855 -27.821 37.615  1.00 54.40  ? 86  TYR A CZ  1 
ATOM   676   O OH  . TYR A 1 86  ? -60.555 -27.558 38.762  1.00 47.83  ? 86  TYR A OH  1 
ATOM   677   N N   . VAL A 1 87  ? -55.121 -27.580 32.065  1.00 47.33  ? 87  VAL A N   1 
ATOM   678   C CA  . VAL A 1 87  ? -54.041 -28.096 31.221  1.00 49.20  ? 87  VAL A CA  1 
ATOM   679   C C   . VAL A 1 87  ? -53.745 -29.541 31.604  1.00 39.29  ? 87  VAL A C   1 
ATOM   680   O O   . VAL A 1 87  ? -53.343 -30.328 30.753  1.00 40.45  ? 87  VAL A O   1 
ATOM   681   C CB  . VAL A 1 87  ? -52.759 -27.235 31.312  1.00 49.81  ? 87  VAL A CB  1 
ATOM   682   C CG1 . VAL A 1 87  ? -51.604 -27.851 30.522  1.00 45.49  ? 87  VAL A CG1 1 
ATOM   683   C CG2 . VAL A 1 87  ? -53.020 -25.797 30.868  1.00 45.77  ? 87  VAL A CG2 1 
ATOM   684   N N   . GLU A 1 88  ? -53.960 -29.845 32.889  1.00 37.23  ? 88  GLU A N   1 
ATOM   685   C CA  . GLU A 1 88  ? -53.782 -31.172 33.465  1.00 41.04  ? 88  GLU A CA  1 
ATOM   686   C C   . GLU A 1 88  ? -54.678 -32.200 32.764  1.00 43.49  ? 88  GLU A C   1 
ATOM   687   O O   . GLU A 1 88  ? -54.289 -33.364 32.629  1.00 41.33  ? 88  GLU A O   1 
ATOM   688   C CB  . GLU A 1 88  ? -54.058 -31.102 34.969  1.00 41.96  ? 88  GLU A CB  1 
ATOM   689   C CG  . GLU A 1 88  ? -53.113 -30.160 35.717  1.00 47.29  ? 88  GLU A CG  1 
ATOM   690   C CD  . GLU A 1 88  ? -53.597 -28.735 36.007  1.00 54.63  ? 88  GLU A CD  1 
ATOM   691   O OE1 . GLU A 1 88  ? -54.108 -28.016 35.058  1.00 53.14  ? 88  GLU A OE1 1 
ATOM   692   O OE2 . GLU A 1 88  ? -53.419 -28.304 37.190  1.00 56.24  ? 88  GLU A OE2 1 
ATOM   693   N N   . GLY A 1 89  ? -55.883 -31.763 32.352  1.00 41.08  ? 89  GLY A N   1 
ATOM   694   C CA  . GLY A 1 89  ? -56.823 -32.626 31.671  1.00 38.09  ? 89  GLY A CA  1 
ATOM   695   C C   . GLY A 1 89  ? -56.329 -32.965 30.270  1.00 39.02  ? 89  GLY A C   1 
ATOM   696   O O   . GLY A 1 89  ? -56.441 -34.098 29.805  1.00 41.53  ? 89  GLY A O   1 
ATOM   697   N N   . HIS A 1 90  ? -55.769 -31.966 29.595  1.00 40.03  ? 90  HIS A N   1 
ATOM   698   C CA  . HIS A 1 90  ? -55.237 -32.193 28.266  1.00 34.05  ? 90  HIS A CA  1 
ATOM   699   C C   . HIS A 1 90  ? -54.066 -33.165 28.338  1.00 32.96  ? 90  HIS A C   1 
ATOM   700   O O   . HIS A 1 90  ? -53.861 -33.959 27.428  1.00 33.66  ? 90  HIS A O   1 
ATOM   701   C CB  . HIS A 1 90  ? -54.829 -30.889 27.610  1.00 34.44  ? 90  HIS A CB  1 
ATOM   702   C CG  . HIS A 1 90  ? -54.393 -31.101 26.199  1.00 38.97  ? 90  HIS A CG  1 
ATOM   703   N ND1 . HIS A 1 90  ? -55.205 -31.687 25.269  1.00 37.57  ? 90  HIS A ND1 1 
ATOM   704   C CD2 . HIS A 1 90  ? -53.201 -30.838 25.596  1.00 38.54  ? 90  HIS A CD2 1 
ATOM   705   C CE1 . HIS A 1 90  ? -54.557 -31.747 24.114  1.00 41.47  ? 90  HIS A CE1 1 
ATOM   706   N NE2 . HIS A 1 90  ? -53.323 -31.229 24.292  1.00 43.90  ? 90  HIS A NE2 1 
ATOM   707   N N   . PHE A 1 91  ? -53.311 -33.119 29.435  1.00 34.75  ? 91  PHE A N   1 
ATOM   708   C CA  . PHE A 1 91  ? -52.192 -34.032 29.620  1.00 39.28  ? 91  PHE A CA  1 
ATOM   709   C C   . PHE A 1 91  ? -52.709 -35.468 29.774  1.00 37.70  ? 91  PHE A C   1 
ATOM   710   O O   . PHE A 1 91  ? -52.129 -36.416 29.251  1.00 43.47  ? 91  PHE A O   1 
ATOM   711   C CB  . PHE A 1 91  ? -51.344 -33.574 30.828  1.00 39.01  ? 91  PHE A CB  1 
ATOM   712   C CG  . PHE A 1 91  ? -50.019 -34.283 30.976  1.00 39.09  ? 91  PHE A CG  1 
ATOM   713   C CD1 . PHE A 1 91  ? -49.144 -34.387 29.890  1.00 38.15  ? 91  PHE A CD1 1 
ATOM   714   C CD2 . PHE A 1 91  ? -49.641 -34.840 32.188  1.00 41.30  ? 91  PHE A CD2 1 
ATOM   715   C CE1 . PHE A 1 91  ? -47.908 -34.999 30.012  1.00 38.14  ? 91  PHE A CE1 1 
ATOM   716   C CE2 . PHE A 1 91  ? -48.415 -35.486 32.298  1.00 43.56  ? 91  PHE A CE2 1 
ATOM   717   C CZ  . PHE A 1 91  ? -47.542 -35.551 31.220  1.00 41.41  ? 91  PHE A CZ  1 
ATOM   718   N N   . TYR A 1 92  ? -53.771 -35.621 30.573  1.00 40.29  ? 92  TYR A N   1 
ATOM   719   C CA  . TYR A 1 92  ? -54.461 -36.888 30.758  1.00 41.37  ? 92  TYR A CA  1 
ATOM   720   C C   . TYR A 1 92  ? -54.884 -37.445 29.394  1.00 34.41  ? 92  TYR A C   1 
ATOM   721   O O   . TYR A 1 92  ? -54.633 -38.585 29.069  1.00 33.26  ? 92  TYR A O   1 
ATOM   722   C CB  . TYR A 1 92  ? -55.655 -36.667 31.699  1.00 42.76  ? 92  TYR A CB  1 
ATOM   723   C CG  . TYR A 1 92  ? -56.364 -37.924 32.120  1.00 42.99  ? 92  TYR A CG  1 
ATOM   724   C CD1 . TYR A 1 92  ? -57.220 -38.583 31.253  1.00 45.77  ? 92  TYR A CD1 1 
ATOM   725   C CD2 . TYR A 1 92  ? -56.145 -38.468 33.376  1.00 41.28  ? 92  TYR A CD2 1 
ATOM   726   C CE1 . TYR A 1 92  ? -57.855 -39.759 31.626  1.00 50.10  ? 92  TYR A CE1 1 
ATOM   727   C CE2 . TYR A 1 92  ? -56.758 -39.647 33.758  1.00 48.51  ? 92  TYR A CE2 1 
ATOM   728   C CZ  . TYR A 1 92  ? -57.618 -40.297 32.883  1.00 51.40  ? 92  TYR A CZ  1 
ATOM   729   O OH  . TYR A 1 92  ? -58.201 -41.483 33.281  1.00 57.34  ? 92  TYR A OH  1 
ATOM   730   N N   . LEU A 1 93  ? -55.474 -36.600 28.573  1.00 31.38  ? 93  LEU A N   1 
ATOM   731   C CA  . LEU A 1 93  ? -55.969 -36.997 27.270  1.00 35.48  ? 93  LEU A CA  1 
ATOM   732   C C   . LEU A 1 93  ? -54.851 -37.505 26.365  1.00 36.73  ? 93  LEU A C   1 
ATOM   733   O O   . LEU A 1 93  ? -55.029 -38.492 25.657  1.00 38.49  ? 93  LEU A O   1 
ATOM   734   C CB  . LEU A 1 93  ? -56.664 -35.790 26.631  1.00 35.21  ? 93  LEU A CB  1 
ATOM   735   C CG  . LEU A 1 93  ? -57.048 -35.995 25.171  1.00 38.04  ? 93  LEU A CG  1 
ATOM   736   C CD1 . LEU A 1 93  ? -57.963 -37.206 25.054  1.00 43.31  ? 93  LEU A CD1 1 
ATOM   737   C CD2 . LEU A 1 93  ? -57.716 -34.757 24.598  1.00 37.84  ? 93  LEU A CD2 1 
ATOM   738   N N   . LEU A 1 94  ? -53.721 -36.795 26.360  1.00 42.95  ? 94  LEU A N   1 
ATOM   739   C CA  . LEU A 1 94  ? -52.591 -37.152 25.515  1.00 42.19  ? 94  LEU A CA  1 
ATOM   740   C C   . LEU A 1 94  ? -51.961 -38.455 25.994  1.00 40.22  ? 94  LEU A C   1 
ATOM   741   O O   . LEU A 1 94  ? -51.545 -39.270 25.178  1.00 45.06  ? 94  LEU A O   1 
ATOM   742   C CB  . LEU A 1 94  ? -51.560 -36.024 25.540  1.00 44.13  ? 94  LEU A CB  1 
ATOM   743   C CG  . LEU A 1 94  ? -52.004 -34.717 24.887  1.00 41.60  ? 94  LEU A CG  1 
ATOM   744   C CD1 . LEU A 1 94  ? -50.847 -33.729 24.853  1.00 39.22  ? 94  LEU A CD1 1 
ATOM   745   C CD2 . LEU A 1 94  ? -52.557 -34.952 23.494  1.00 40.57  ? 94  LEU A CD2 1 
ATOM   746   N N   . LEU A 1 95  ? -51.910 -38.670 27.306  1.00 36.33  ? 95  LEU A N   1 
ATOM   747   C CA  . LEU A 1 95  ? -51.346 -39.913 27.819  1.00 40.25  ? 95  LEU A CA  1 
ATOM   748   C C   . LEU A 1 95  ? -52.255 -41.112 27.538  1.00 38.50  ? 95  LEU A C   1 
ATOM   749   O O   . LEU A 1 95  ? -51.758 -42.157 27.143  1.00 41.27  ? 95  LEU A O   1 
ATOM   750   C CB  . LEU A 1 95  ? -51.110 -39.784 29.322  1.00 41.07  ? 95  LEU A CB  1 
ATOM   751   C CG  . LEU A 1 95  ? -49.790 -39.152 29.728  1.00 44.75  ? 95  LEU A CG  1 
ATOM   752   C CD1 . LEU A 1 95  ? -49.786 -38.955 31.241  1.00 47.26  ? 95  LEU A CD1 1 
ATOM   753   C CD2 . LEU A 1 95  ? -48.598 -40.009 29.265  1.00 42.56  ? 95  LEU A CD2 1 
ATOM   754   N N   . THR A 1 96  ? -53.563 -40.960 27.772  1.00 36.24  ? 96  THR A N   1 
ATOM   755   C CA  . THR A 1 96  ? -54.453 -42.104 27.900  1.00 41.28  ? 96  THR A CA  1 
ATOM   756   C C   . THR A 1 96  ? -55.231 -42.315 26.618  1.00 44.55  ? 96  THR A C   1 
ATOM   757   O O   . THR A 1 96  ? -55.526 -43.451 26.287  1.00 60.28  ? 96  THR A O   1 
ATOM   758   C CB  . THR A 1 96  ? -55.485 -41.967 29.040  1.00 43.48  ? 96  THR A CB  1 
ATOM   759   O OG1 . THR A 1 96  ? -56.416 -40.919 28.734  1.00 35.84  ? 96  THR A OG1 1 
ATOM   760   C CG2 . THR A 1 96  ? -54.831 -41.752 30.398  1.00 40.54  ? 96  THR A CG2 1 
ATOM   761   N N   . GLY A 1 97  ? -55.581 -41.223 25.938  1.00 44.40  ? 97  GLY A N   1 
ATOM   762   C CA  . GLY A 1 97  ? -56.523 -41.272 24.834  1.00 44.69  ? 97  GLY A CA  1 
ATOM   763   C C   . GLY A 1 97  ? -57.959 -40.935 25.257  1.00 49.54  ? 97  GLY A C   1 
ATOM   764   O O   . GLY A 1 97  ? -58.825 -40.825 24.393  1.00 51.23  ? 97  GLY A O   1 
ATOM   765   N N   . ASP A 1 98  ? -58.199 -40.735 26.566  1.00 50.06  ? 98  ASP A N   1 
ATOM   766   C CA  . ASP A 1 98  ? -59.541 -40.565 27.105  1.00 51.65  ? 98  ASP A CA  1 
ATOM   767   C C   . ASP A 1 98  ? -59.754 -39.127 27.566  1.00 51.52  ? 98  ASP A C   1 
ATOM   768   O O   . ASP A 1 98  ? -58.858 -38.543 28.167  1.00 51.15  ? 98  ASP A O   1 
ATOM   769   C CB  . ASP A 1 98  ? -59.752 -41.399 28.372  1.00 62.22  ? 98  ASP A CB  1 
ATOM   770   C CG  . ASP A 1 98  ? -59.669 -42.906 28.206  1.00 76.97  ? 98  ASP A CG  1 
ATOM   771   O OD1 . ASP A 1 98  ? -59.796 -43.386 27.040  1.00 73.00  ? 98  ASP A OD1 1 
ATOM   772   O OD2 . ASP A 1 98  ? -59.470 -43.592 29.259  1.00 83.02  ? 98  ASP A OD2 1 
ATOM   773   N N   . VAL A 1 99  ? -60.961 -38.584 27.361  1.00 46.68  ? 99  VAL A N   1 
ATOM   774   C CA  . VAL A 1 99  ? -61.336 -37.350 28.038  1.00 46.43  ? 99  VAL A CA  1 
ATOM   775   C C   . VAL A 1 99  ? -61.559 -37.676 29.512  1.00 46.16  ? 99  VAL A C   1 
ATOM   776   O O   . VAL A 1 99  ? -62.355 -38.536 29.831  1.00 50.54  ? 99  VAL A O   1 
ATOM   777   C CB  . VAL A 1 99  ? -62.579 -36.670 27.438  1.00 42.52  ? 99  VAL A CB  1 
ATOM   778   C CG1 . VAL A 1 99  ? -62.938 -35.404 28.217  1.00 46.80  ? 99  VAL A CG1 1 
ATOM   779   C CG2 . VAL A 1 99  ? -62.404 -36.354 25.957  1.00 40.76  ? 99  VAL A CG2 1 
ATOM   780   N N   . PRO A 1 100 ? -60.848 -37.037 30.463  1.00 49.31  ? 100 PRO A N   1 
ATOM   781   C CA  . PRO A 1 100 ? -61.072 -37.300 31.885  1.00 46.83  ? 100 PRO A CA  1 
ATOM   782   C C   . PRO A 1 100 ? -62.325 -36.663 32.493  1.00 45.07  ? 100 PRO A C   1 
ATOM   783   O O   . PRO A 1 100 ? -62.813 -35.635 32.021  1.00 42.68  ? 100 PRO A O   1 
ATOM   784   C CB  . PRO A 1 100 ? -59.801 -36.716 32.535  1.00 46.58  ? 100 PRO A CB  1 
ATOM   785   C CG  . PRO A 1 100 ? -59.426 -35.583 31.629  1.00 47.54  ? 100 PRO A CG  1 
ATOM   786   C CD  . PRO A 1 100 ? -59.767 -36.059 30.230  1.00 48.86  ? 100 PRO A CD  1 
ATOM   787   N N   . THR A 1 101 ? -62.833 -37.316 33.549  1.00 43.64  ? 101 THR A N   1 
ATOM   788   C CA  . THR A 1 101 ? -63.912 -36.798 34.375  1.00 47.12  ? 101 THR A CA  1 
ATOM   789   C C   . THR A 1 101 ? -63.352 -35.648 35.203  1.00 51.73  ? 101 THR A C   1 
ATOM   790   O O   . THR A 1 101 ? -62.146 -35.540 35.391  1.00 50.02  ? 101 THR A O   1 
ATOM   791   C CB  . THR A 1 101 ? -64.542 -37.900 35.256  1.00 44.78  ? 101 THR A CB  1 
ATOM   792   O OG1 . THR A 1 101 ? -63.669 -38.257 36.329  1.00 44.30  ? 101 THR A OG1 1 
ATOM   793   C CG2 . THR A 1 101 ? -64.886 -39.163 34.486  1.00 41.62  ? 101 THR A CG2 1 
ATOM   794   N N   . GLU A 1 102 ? -64.244 -34.804 35.716  1.00 59.03  ? 102 GLU A N   1 
ATOM   795   C CA  . GLU A 1 102 ? -63.878 -33.737 36.632  1.00 63.81  ? 102 GLU A CA  1 
ATOM   796   C C   . GLU A 1 102 ? -63.065 -34.303 37.801  1.00 61.62  ? 102 GLU A C   1 
ATOM   797   O O   . GLU A 1 102 ? -62.259 -33.597 38.381  1.00 63.46  ? 102 GLU A O   1 
ATOM   798   C CB  . GLU A 1 102 ? -65.157 -33.038 37.114  1.00 70.05  ? 102 GLU A CB  1 
ATOM   799   C CG  . GLU A 1 102 ? -64.970 -31.696 37.786  1.00 78.48  ? 102 GLU A CG  1 
ATOM   800   C CD  . GLU A 1 102 ? -65.971 -31.398 38.902  1.00 87.23  ? 102 GLU A CD  1 
ATOM   801   O OE1 . GLU A 1 102 ? -67.193 -31.554 38.688  1.00 91.23  ? 102 GLU A OE1 1 
ATOM   802   O OE2 . GLU A 1 102 ? -65.529 -31.006 39.995  1.00 86.47  ? 102 GLU A OE2 1 
ATOM   803   N N   . LYS A 1 103 ? -63.246 -35.584 38.139  1.00 73.99  ? 103 LYS A N   1 
ATOM   804   C CA  . LYS A 1 103 ? -62.613 -36.159 39.315  1.00 68.44  ? 103 LYS A CA  1 
ATOM   805   C C   . LYS A 1 103 ? -61.181 -36.593 38.988  1.00 60.83  ? 103 LYS A C   1 
ATOM   806   O O   . LYS A 1 103 ? -60.292 -36.401 39.815  1.00 60.16  ? 103 LYS A O   1 
ATOM   807   C CB  . LYS A 1 103 ? -63.499 -37.283 39.864  1.00 75.78  ? 103 LYS A CB  1 
ATOM   808   C CG  . LYS A 1 103 ? -63.462 -37.446 41.382  1.00 90.26  ? 103 LYS A CG  1 
ATOM   809   C CD  . LYS A 1 103 ? -62.478 -38.502 41.845  1.00 101.76 ? 103 LYS A CD  1 
ATOM   810   C CE  . LYS A 1 103 ? -62.988 -39.907 41.606  1.00 106.76 ? 103 LYS A CE  1 
ATOM   811   N NZ  . LYS A 1 103 ? -61.907 -40.833 41.191  1.00 110.06 ? 103 LYS A NZ  1 
ATOM   812   N N   . GLU A 1 104 ? -60.956 -37.145 37.784  1.00 50.00  ? 104 GLU A N   1 
ATOM   813   C CA  . GLU A 1 104 ? -59.631 -37.567 37.334  1.00 49.85  ? 104 GLU A CA  1 
ATOM   814   C C   . GLU A 1 104 ? -58.671 -36.406 37.067  1.00 52.54  ? 104 GLU A C   1 
ATOM   815   O O   . GLU A 1 104 ? -57.461 -36.566 37.216  1.00 55.67  ? 104 GLU A O   1 
ATOM   816   C CB  . GLU A 1 104 ? -59.723 -38.360 36.036  1.00 45.75  ? 104 GLU A CB  1 
ATOM   817   C CG  . GLU A 1 104 ? -60.533 -39.631 36.200  1.00 50.40  ? 104 GLU A CG  1 
ATOM   818   C CD  . GLU A 1 104 ? -60.967 -40.285 34.904  1.00 46.03  ? 104 GLU A CD  1 
ATOM   819   O OE1 . GLU A 1 104 ? -61.508 -39.592 34.016  1.00 45.00  ? 104 GLU A OE1 1 
ATOM   820   O OE2 . GLU A 1 104 ? -60.771 -41.489 34.800  1.00 52.66  ? 104 GLU A OE2 1 
ATOM   821   N N   . VAL A 1 105 ? -59.200 -35.259 36.628  1.00 57.03  ? 105 VAL A N   1 
ATOM   822   C CA  . VAL A 1 105 ? -58.404 -34.057 36.430  1.00 57.98  ? 105 VAL A CA  1 
ATOM   823   C C   . VAL A 1 105 ? -57.870 -33.558 37.772  1.00 62.62  ? 105 VAL A C   1 
ATOM   824   O O   . VAL A 1 105 ? -56.752 -33.044 37.829  1.00 61.55  ? 105 VAL A O   1 
ATOM   825   C CB  . VAL A 1 105 ? -59.206 -32.953 35.722  1.00 56.88  ? 105 VAL A CB  1 
ATOM   826   C CG1 . VAL A 1 105 ? -58.457 -31.639 35.726  1.00 65.40  ? 105 VAL A CG1 1 
ATOM   827   C CG2 . VAL A 1 105 ? -59.553 -33.332 34.292  1.00 61.48  ? 105 VAL A CG2 1 
ATOM   828   N N   . LYS A 1 106 ? -58.675 -33.705 38.834  1.00 66.08  ? 106 LYS A N   1 
ATOM   829   C CA  . LYS A 1 106 ? -58.324 -33.163 40.132  1.00 64.04  ? 106 LYS A CA  1 
ATOM   830   C C   . LYS A 1 106 ? -57.256 -34.033 40.787  1.00 67.79  ? 106 LYS A C   1 
ATOM   831   O O   . LYS A 1 106 ? -56.486 -33.546 41.609  1.00 70.72  ? 106 LYS A O   1 
ATOM   832   C CB  . LYS A 1 106 ? -59.569 -32.972 40.995  1.00 70.97  ? 106 LYS A CB  1 
ATOM   833   C CG  . LYS A 1 106 ? -60.536 -31.934 40.434  1.00 79.52  ? 106 LYS A CG  1 
ATOM   834   C CD  . LYS A 1 106 ? -61.448 -31.317 41.466  1.00 85.97  ? 106 LYS A CD  1 
ATOM   835   C CE  . LYS A 1 106 ? -60.769 -30.210 42.246  1.00 95.53  ? 106 LYS A CE  1 
ATOM   836   N NZ  . LYS A 1 106 ? -61.698 -29.597 43.221  1.00 104.63 ? 106 LYS A NZ  1 
ATOM   837   N N   . GLU A 1 107 ? -57.166 -35.299 40.398  1.00 66.01  ? 107 GLU A N   1 
ATOM   838   C CA  . GLU A 1 107 ? -56.136 -36.149 40.961  1.00 71.26  ? 107 GLU A CA  1 
ATOM   839   C C   . GLU A 1 107 ? -54.795 -35.769 40.347  1.00 62.58  ? 107 GLU A C   1 
ATOM   840   O O   . GLU A 1 107 ? -53.792 -35.740 41.055  1.00 62.14  ? 107 GLU A O   1 
ATOM   841   C CB  . GLU A 1 107 ? -56.485 -37.621 40.745  1.00 84.17  ? 107 GLU A CB  1 
ATOM   842   C CG  . GLU A 1 107 ? -57.771 -38.019 41.441  1.00 94.65  ? 107 GLU A CG  1 
ATOM   843   C CD  . GLU A 1 107 ? -58.139 -39.491 41.313  1.00 99.97  ? 107 GLU A CD  1 
ATOM   844   O OE1 . GLU A 1 107 ? -58.416 -39.951 40.173  1.00 77.18  ? 107 GLU A OE1 1 
ATOM   845   O OE2 . GLU A 1 107 ? -58.164 -40.183 42.364  1.00 114.80 ? 107 GLU A OE2 1 
ATOM   846   N N   . VAL A 1 108 ? -54.794 -35.480 39.038  1.00 54.19  ? 108 VAL A N   1 
ATOM   847   C CA  . VAL A 1 108 ? -53.581 -35.094 38.338  1.00 53.98  ? 108 VAL A CA  1 
ATOM   848   C C   . VAL A 1 108 ? -53.071 -33.764 38.888  1.00 52.13  ? 108 VAL A C   1 
ATOM   849   O O   . VAL A 1 108 ? -51.876 -33.631 39.171  1.00 48.29  ? 108 VAL A O   1 
ATOM   850   C CB  . VAL A 1 108 ? -53.800 -34.989 36.819  1.00 53.98  ? 108 VAL A CB  1 
ATOM   851   C CG1 . VAL A 1 108 ? -52.595 -34.370 36.101  1.00 56.07  ? 108 VAL A CG1 1 
ATOM   852   C CG2 . VAL A 1 108 ? -54.152 -36.347 36.230  1.00 57.30  ? 108 VAL A CG2 1 
ATOM   853   N N   . ALA A 1 109 ? -53.994 -32.796 39.002  1.00 45.67  ? 109 ALA A N   1 
ATOM   854   C CA  . ALA A 1 109 ? -53.699 -31.472 39.517  1.00 48.29  ? 109 ALA A CA  1 
ATOM   855   C C   . ALA A 1 109 ? -53.067 -31.561 40.899  1.00 45.59  ? 109 ALA A C   1 
ATOM   856   O O   . ALA A 1 109 ? -52.139 -30.812 41.173  1.00 49.10  ? 109 ALA A O   1 
ATOM   857   C CB  . ALA A 1 109 ? -54.947 -30.614 39.541  1.00 52.91  ? 109 ALA A CB  1 
ATOM   858   N N   . GLU A 1 110 ? -53.588 -32.453 41.749  1.00 46.98  ? 110 GLU A N   1 
ATOM   859   C CA  . GLU A 1 110 ? -53.022 -32.694 43.071  1.00 49.97  ? 110 GLU A CA  1 
ATOM   860   C C   . GLU A 1 110 ? -51.646 -33.336 42.940  1.00 42.72  ? 110 GLU A C   1 
ATOM   861   O O   . GLU A 1 110 ? -50.785 -33.072 43.761  1.00 41.00  ? 110 GLU A O   1 
ATOM   862   C CB  . GLU A 1 110 ? -53.895 -33.595 43.960  1.00 55.67  ? 110 GLU A CB  1 
ATOM   863   C CG  . GLU A 1 110 ? -55.165 -32.932 44.493  1.00 68.44  ? 110 GLU A CG  1 
ATOM   864   C CD  . GLU A 1 110 ? -55.020 -31.593 45.215  1.00 80.57  ? 110 GLU A CD  1 
ATOM   865   O OE1 . GLU A 1 110 ? -54.455 -31.554 46.348  1.00 89.49  ? 110 GLU A OE1 1 
ATOM   866   O OE2 . GLU A 1 110 ? -55.478 -30.577 44.638  1.00 76.26  ? 110 GLU A OE2 1 
ATOM   867   N N   . GLU A 1 111 ? -51.446 -34.188 41.935  1.00 40.30  ? 111 GLU A N   1 
ATOM   868   C CA  . GLU A 1 111 ? -50.153 -34.825 41.780  1.00 49.54  ? 111 GLU A CA  1 
ATOM   869   C C   . GLU A 1 111 ? -49.120 -33.798 41.301  1.00 45.25  ? 111 GLU A C   1 
ATOM   870   O O   . GLU A 1 111 ? -47.953 -33.873 41.678  1.00 44.53  ? 111 GLU A O   1 
ATOM   871   C CB  . GLU A 1 111 ? -50.210 -36.057 40.876  1.00 50.82  ? 111 GLU A CB  1 
ATOM   872   C CG  . GLU A 1 111 ? -49.006 -36.983 41.047  1.00 59.99  ? 111 GLU A CG  1 
ATOM   873   C CD  . GLU A 1 111 ? -48.691 -37.459 42.475  1.00 69.67  ? 111 GLU A CD  1 
ATOM   874   O OE1 . GLU A 1 111 ? -49.622 -37.908 43.165  1.00 88.04  ? 111 GLU A OE1 1 
ATOM   875   O OE2 . GLU A 1 111 ? -47.511 -37.390 42.918  1.00 66.55  ? 111 GLU A OE2 1 
ATOM   876   N N   . PHE A 1 112 ? -49.542 -32.822 40.498  1.00 43.72  ? 112 PHE A N   1 
ATOM   877   C CA  . PHE A 1 112 ? -48.631 -31.789 40.036  1.00 43.92  ? 112 PHE A CA  1 
ATOM   878   C C   . PHE A 1 112 ? -48.214 -30.866 41.183  1.00 46.19  ? 112 PHE A C   1 
ATOM   879   O O   . PHE A 1 112 ? -47.054 -30.466 41.262  1.00 45.87  ? 112 PHE A O   1 
ATOM   880   C CB  . PHE A 1 112 ? -49.258 -30.983 38.906  1.00 44.11  ? 112 PHE A CB  1 
ATOM   881   C CG  . PHE A 1 112 ? -49.065 -31.576 37.537  1.00 44.87  ? 112 PHE A CG  1 
ATOM   882   C CD1 . PHE A 1 112 ? -48.604 -32.862 37.371  1.00 42.29  ? 112 PHE A CD1 1 
ATOM   883   C CD2 . PHE A 1 112 ? -49.379 -30.836 36.407  1.00 48.12  ? 112 PHE A CD2 1 
ATOM   884   C CE1 . PHE A 1 112 ? -48.440 -33.386 36.100  1.00 47.03  ? 112 PHE A CE1 1 
ATOM   885   C CE2 . PHE A 1 112 ? -49.208 -31.366 35.137  1.00 46.99  ? 112 PHE A CE2 1 
ATOM   886   C CZ  . PHE A 1 112 ? -48.741 -32.642 34.986  1.00 43.25  ? 112 PHE A CZ  1 
ATOM   887   N N   . LYS A 1 113 ? -49.169 -30.542 42.062  1.00 44.91  ? 113 LYS A N   1 
ATOM   888   C CA  . LYS A 1 113 ? -48.930 -29.685 43.205  1.00 45.52  ? 113 LYS A CA  1 
ATOM   889   C C   . LYS A 1 113 ? -47.845 -30.274 44.098  1.00 44.57  ? 113 LYS A C   1 
ATOM   890   O O   . LYS A 1 113 ? -46.989 -29.532 44.561  1.00 41.84  ? 113 LYS A O   1 
ATOM   891   C CB  . LYS A 1 113 ? -50.249 -29.428 43.936  1.00 50.57  ? 113 LYS A CB  1 
ATOM   892   C CG  . LYS A 1 113 ? -51.093 -28.378 43.232  1.00 59.73  ? 113 LYS A CG  1 
ATOM   893   C CD  . LYS A 1 113 ? -52.568 -28.349 43.544  1.00 63.72  ? 113 LYS A CD  1 
ATOM   894   C CE  . LYS A 1 113 ? -53.289 -27.360 42.648  1.00 59.62  ? 113 LYS A CE  1 
ATOM   895   N NZ  . LYS A 1 113 ? -54.744 -27.387 42.876  1.00 62.38  ? 113 LYS A NZ  1 
ATOM   896   N N   . LYS A 1 114 ? -47.847 -31.599 44.278  1.00 45.89  ? 114 LYS A N   1 
ATOM   897   C CA  . LYS A 1 114 ? -46.841 -32.272 45.089  1.00 49.16  ? 114 LYS A CA  1 
ATOM   898   C C   . LYS A 1 114 ? -45.446 -32.174 44.450  1.00 47.25  ? 114 LYS A C   1 
ATOM   899   O O   . LYS A 1 114 ? -44.441 -32.267 45.147  1.00 42.35  ? 114 LYS A O   1 
ATOM   900   C CB  . LYS A 1 114 ? -47.296 -33.709 45.371  1.00 54.99  ? 114 LYS A CB  1 
ATOM   901   C CG  . LYS A 1 114 ? -48.437 -33.785 46.391  1.00 74.51  ? 114 LYS A CG  1 
ATOM   902   C CD  . LYS A 1 114 ? -49.040 -35.161 46.665  1.00 81.89  ? 114 LYS A CD  1 
ATOM   903   C CE  . LYS A 1 114 ? -48.123 -36.031 47.497  1.00 92.69  ? 114 LYS A CE  1 
ATOM   904   N NZ  . LYS A 1 114 ? -48.737 -37.347 47.792  1.00 94.97  ? 114 LYS A NZ  1 
ATOM   905   N N   . ARG A 1 115 ? -45.356 -31.918 43.144  1.00 41.24  ? 115 ARG A N   1 
ATOM   906   C CA  . ARG A 1 115 ? -44.096 -32.059 42.440  1.00 40.34  ? 115 ARG A CA  1 
ATOM   907   C C   . ARG A 1 115 ? -43.606 -30.756 41.801  1.00 40.21  ? 115 ARG A C   1 
ATOM   908   O O   . ARG A 1 115 ? -42.672 -30.817 41.008  1.00 46.18  ? 115 ARG A O   1 
ATOM   909   C CB  . ARG A 1 115 ? -44.266 -33.073 41.302  1.00 40.40  ? 115 ARG A CB  1 
ATOM   910   C CG  . ARG A 1 115 ? -44.519 -34.502 41.748  1.00 41.02  ? 115 ARG A CG  1 
ATOM   911   C CD  . ARG A 1 115 ? -44.845 -35.353 40.543  1.00 42.14  ? 115 ARG A CD  1 
ATOM   912   N NE  . ARG A 1 115 ? -45.372 -36.664 40.904  1.00 47.22  ? 115 ARG A NE  1 
ATOM   913   C CZ  . ARG A 1 115 ? -44.916 -37.829 40.451  1.00 42.15  ? 115 ARG A CZ  1 
ATOM   914   N NH1 . ARG A 1 115 ? -43.696 -37.965 39.961  1.00 31.48  ? 115 ARG A NH1 1 
ATOM   915   N NH2 . ARG A 1 115 ? -45.712 -38.875 40.497  1.00 47.75  ? 115 ARG A NH2 1 
ATOM   916   N N   . ARG A 1 116 ? -44.208 -29.591 42.080  1.00 35.80  ? 116 ARG A N   1 
ATOM   917   C CA  . ARG A 1 116 ? -43.918 -28.438 41.230  1.00 40.20  ? 116 ARG A CA  1 
ATOM   918   C C   . ARG A 1 116 ? -42.796 -27.538 41.797  1.00 39.45  ? 116 ARG A C   1 
ATOM   919   O O   . ARG A 1 116 ? -42.384 -26.531 41.182  1.00 35.87  ? 116 ARG A O   1 
ATOM   920   C CB  . ARG A 1 116 ? -45.209 -27.677 40.902  1.00 41.87  ? 116 ARG A CB  1 
ATOM   921   C CG  . ARG A 1 116 ? -45.987 -27.137 42.090  1.00 42.00  ? 116 ARG A CG  1 
ATOM   922   C CD  . ARG A 1 116 ? -46.938 -26.040 41.610  1.00 41.37  ? 116 ARG A CD  1 
ATOM   923   N NE  . ARG A 1 116 ? -48.294 -26.409 41.194  1.00 41.28  ? 116 ARG A NE  1 
ATOM   924   C CZ  . ARG A 1 116 ? -49.398 -25.685 41.462  1.00 41.79  ? 116 ARG A CZ  1 
ATOM   925   N NH1 . ARG A 1 116 ? -49.482 -24.966 42.582  1.00 34.54  ? 116 ARG A NH1 1 
ATOM   926   N NH2 . ARG A 1 116 ? -50.408 -25.673 40.588  1.00 42.30  ? 116 ARG A NH2 1 
ATOM   927   N N   . ALA A 1 117 ? -42.247 -27.922 42.948  1.00 34.84  ? 117 ALA A N   1 
ATOM   928   C CA  . ALA A 1 117 ? -41.201 -27.129 43.558  1.00 36.15  ? 117 ALA A CA  1 
ATOM   929   C C   . ALA A 1 117 ? -39.888 -27.371 42.817  1.00 35.87  ? 117 ALA A C   1 
ATOM   930   O O   . ALA A 1 117 ? -39.463 -28.495 42.580  1.00 37.30  ? 117 ALA A O   1 
ATOM   931   C CB  . ALA A 1 117 ? -41.094 -27.413 45.035  1.00 36.58  ? 117 ALA A CB  1 
ATOM   932   N N   . LEU A 1 118 ? -39.267 -26.257 42.455  1.00 40.27  ? 118 LEU A N   1 
ATOM   933   C CA  . LEU A 1 118 ? -38.020 -26.183 41.721  1.00 42.52  ? 118 LEU A CA  1 
ATOM   934   C C   . LEU A 1 118 ? -36.850 -26.442 42.677  1.00 41.46  ? 118 LEU A C   1 
ATOM   935   O O   . LEU A 1 118 ? -36.772 -25.830 43.753  1.00 39.20  ? 118 LEU A O   1 
ATOM   936   C CB  . LEU A 1 118 ? -37.981 -24.762 41.148  1.00 46.20  ? 118 LEU A CB  1 
ATOM   937   C CG  . LEU A 1 118 ? -37.382 -24.617 39.759  1.00 50.76  ? 118 LEU A CG  1 
ATOM   938   C CD1 . LEU A 1 118 ? -38.172 -25.447 38.776  1.00 52.42  ? 118 LEU A CD1 1 
ATOM   939   C CD2 . LEU A 1 118 ? -37.375 -23.154 39.349  1.00 51.06  ? 118 LEU A CD2 1 
ATOM   940   N N   . PRO A 1 119 ? -35.918 -27.371 42.360  1.00 37.64  ? 119 PRO A N   1 
ATOM   941   C CA  . PRO A 1 119 ? -34.732 -27.572 43.198  1.00 40.48  ? 119 PRO A CA  1 
ATOM   942   C C   . PRO A 1 119 ? -33.962 -26.272 43.387  1.00 37.01  ? 119 PRO A C   1 
ATOM   943   O O   . PRO A 1 119 ? -33.820 -25.528 42.426  1.00 36.41  ? 119 PRO A O   1 
ATOM   944   C CB  . PRO A 1 119 ? -33.874 -28.550 42.381  1.00 38.81  ? 119 PRO A CB  1 
ATOM   945   C CG  . PRO A 1 119 ? -34.890 -29.323 41.588  1.00 39.90  ? 119 PRO A CG  1 
ATOM   946   C CD  . PRO A 1 119 ? -35.962 -28.305 41.233  1.00 38.56  ? 119 PRO A CD  1 
ATOM   947   N N   . GLU A 1 120 ? -33.455 -26.030 44.602  1.00 35.65  ? 120 GLU A N   1 
ATOM   948   C CA  . GLU A 1 120 ? -32.612 -24.875 44.849  1.00 37.27  ? 120 GLU A CA  1 
ATOM   949   C C   . GLU A 1 120 ? -31.446 -24.796 43.881  1.00 31.63  ? 120 GLU A C   1 
ATOM   950   O O   . GLU A 1 120 ? -31.175 -23.713 43.377  1.00 36.82  ? 120 GLU A O   1 
ATOM   951   C CB  . GLU A 1 120 ? -32.103 -24.820 46.291  1.00 47.33  ? 120 GLU A CB  1 
ATOM   952   C CG  . GLU A 1 120 ? -33.138 -24.235 47.236  1.00 61.39  ? 120 GLU A CG  1 
ATOM   953   C CD  . GLU A 1 120 ? -33.669 -22.880 46.777  1.00 80.59  ? 120 GLU A CD  1 
ATOM   954   O OE1 . GLU A 1 120 ? -32.839 -21.940 46.649  1.00 90.04  ? 120 GLU A OE1 1 
ATOM   955   O OE2 . GLU A 1 120 ? -34.897 -22.772 46.505  1.00 82.86  ? 120 GLU A OE2 1 
ATOM   956   N N   . TYR A 1 121 ? -30.773 -25.915 43.607  1.00 28.70  ? 121 TYR A N   1 
ATOM   957   C CA  . TYR A 1 121 ? -29.579 -25.880 42.775  1.00 28.31  ? 121 TYR A CA  1 
ATOM   958   C C   . TYR A 1 121 ? -29.877 -25.419 41.352  1.00 30.00  ? 121 TYR A C   1 
ATOM   959   O O   . TYR A 1 121 ? -28.969 -24.942 40.684  1.00 32.39  ? 121 TYR A O   1 
ATOM   960   C CB  . TYR A 1 121 ? -28.849 -27.219 42.777  1.00 29.41  ? 121 TYR A CB  1 
ATOM   961   C CG  . TYR A 1 121 ? -29.589 -28.364 42.134  1.00 31.00  ? 121 TYR A CG  1 
ATOM   962   C CD1 . TYR A 1 121 ? -29.685 -28.483 40.753  1.00 30.71  ? 121 TYR A CD1 1 
ATOM   963   C CD2 . TYR A 1 121 ? -30.149 -29.356 42.918  1.00 30.90  ? 121 TYR A CD2 1 
ATOM   964   C CE1 . TYR A 1 121 ? -30.363 -29.537 40.173  1.00 32.77  ? 121 TYR A CE1 1 
ATOM   965   C CE2 . TYR A 1 121 ? -30.842 -30.408 42.352  1.00 33.87  ? 121 TYR A CE2 1 
ATOM   966   C CZ  . TYR A 1 121 ? -30.950 -30.492 40.979  1.00 35.90  ? 121 TYR A CZ  1 
ATOM   967   O OH  . TYR A 1 121 ? -31.620 -31.549 40.434  1.00 47.26  ? 121 TYR A OH  1 
ATOM   968   N N   . VAL A 1 122 ? -31.119 -25.577 40.871  1.00 30.33  ? 122 VAL A N   1 
ATOM   969   C CA  . VAL A 1 122 ? -31.495 -25.079 39.553  1.00 29.04  ? 122 VAL A CA  1 
ATOM   970   C C   . VAL A 1 122 ? -31.516 -23.547 39.557  1.00 29.72  ? 122 VAL A C   1 
ATOM   971   O O   . VAL A 1 122 ? -31.071 -22.908 38.620  1.00 31.83  ? 122 VAL A O   1 
ATOM   972   C CB  . VAL A 1 122 ? -32.880 -25.610 39.128  1.00 32.48  ? 122 VAL A CB  1 
ATOM   973   C CG1 . VAL A 1 122 ? -33.450 -24.833 37.944  1.00 30.38  ? 122 VAL A CG1 1 
ATOM   974   C CG2 . VAL A 1 122 ? -32.864 -27.111 38.854  1.00 34.11  ? 122 VAL A CG2 1 
ATOM   975   N N   . LYS A 1 123 ? -32.079 -22.934 40.595  1.00 31.62  ? 123 LYS A N   1 
ATOM   976   C CA  . LYS A 1 123 ? -31.965 -21.500 40.749  1.00 32.14  ? 123 LYS A CA  1 
ATOM   977   C C   . LYS A 1 123 ? -30.489 -21.045 40.842  1.00 35.58  ? 123 LYS A C   1 
ATOM   978   O O   . LYS A 1 123 ? -30.105 -20.059 40.203  1.00 34.25  ? 123 LYS A O   1 
ATOM   979   C CB  . LYS A 1 123 ? -32.744 -21.096 41.992  1.00 32.86  ? 123 LYS A CB  1 
ATOM   980   C CG  . LYS A 1 123 ? -34.207 -21.477 41.972  1.00 37.56  ? 123 LYS A CG  1 
ATOM   981   C CD  . LYS A 1 123 ? -34.860 -21.040 43.258  1.00 40.66  ? 123 LYS A CD  1 
ATOM   982   C CE  . LYS A 1 123 ? -36.286 -21.514 43.384  1.00 44.88  ? 123 LYS A CE  1 
ATOM   983   N NZ  . LYS A 1 123 ? -36.789 -21.136 44.716  1.00 49.91  ? 123 LYS A NZ  1 
ATOM   984   N N   . ASP A 1 124 ? -29.670 -21.732 41.652  1.00 29.16  ? 124 ASP A N   1 
ATOM   985   C CA  . ASP A 1 124 ? -28.255 -21.427 41.752  1.00 33.69  ? 124 ASP A CA  1 
ATOM   986   C C   . ASP A 1 124 ? -27.580 -21.494 40.380  1.00 32.87  ? 124 ASP A C   1 
ATOM   987   O O   . ASP A 1 124 ? -26.701 -20.687 40.059  1.00 31.47  ? 124 ASP A O   1 
ATOM   988   C CB  . ASP A 1 124 ? -27.512 -22.448 42.615  1.00 45.59  ? 124 ASP A CB  1 
ATOM   989   C CG  . ASP A 1 124 ? -28.009 -22.600 44.046  1.00 58.64  ? 124 ASP A CG  1 
ATOM   990   O OD1 . ASP A 1 124 ? -28.653 -21.627 44.557  1.00 61.94  ? 124 ASP A OD1 1 
ATOM   991   O OD2 . ASP A 1 124 ? -27.757 -23.713 44.639  1.00 63.54  ? 124 ASP A OD2 1 
ATOM   992   N N   . THR A 1 125 ? -27.961 -22.488 39.585  1.00 29.45  ? 125 THR A N   1 
ATOM   993   C CA  . THR A 1 125 ? -27.367 -22.672 38.274  1.00 34.89  ? 125 THR A CA  1 
ATOM   994   C C   . THR A 1 125 ? -27.694 -21.483 37.378  1.00 35.37  ? 125 THR A C   1 
ATOM   995   O O   . THR A 1 125 ? -26.793 -20.899 36.774  1.00 41.89  ? 125 THR A O   1 
ATOM   996   C CB  . THR A 1 125 ? -27.800 -24.008 37.641  1.00 38.49  ? 125 THR A CB  1 
ATOM   997   O OG1 . THR A 1 125 ? -27.347 -25.082 38.450  1.00 40.06  ? 125 THR A OG1 1 
ATOM   998   C CG2 . THR A 1 125 ? -27.249 -24.249 36.252  1.00 39.18  ? 125 THR A CG2 1 
ATOM   999   N N   . LEU A 1 126 ? -28.980 -21.134 37.285  1.00 35.91  ? 126 LEU A N   1 
ATOM   1000  C CA  . LEU A 1 126 ? -29.428 -20.015 36.458  1.00 34.70  ? 126 LEU A CA  1 
ATOM   1001  C C   . LEU A 1 126 ? -28.786 -18.682 36.867  1.00 34.15  ? 126 LEU A C   1 
ATOM   1002  O O   . LEU A 1 126 ? -28.661 -17.762 36.063  1.00 38.83  ? 126 LEU A O   1 
ATOM   1003  C CB  . LEU A 1 126 ? -30.947 -19.922 36.586  1.00 34.86  ? 126 LEU A CB  1 
ATOM   1004  C CG  . LEU A 1 126 ? -31.766 -21.062 35.963  1.00 40.85  ? 126 LEU A CG  1 
ATOM   1005  C CD1 . LEU A 1 126 ? -33.264 -20.779 36.073  1.00 42.10  ? 126 LEU A CD1 1 
ATOM   1006  C CD2 . LEU A 1 126 ? -31.396 -21.336 34.511  1.00 37.54  ? 126 LEU A CD2 1 
ATOM   1007  N N   . LYS A 1 127 ? -28.438 -18.517 38.145  1.00 37.88  ? 127 LYS A N   1 
ATOM   1008  C CA  . LYS A 1 127 ? -27.759 -17.315 38.609  1.00 35.81  ? 127 LYS A CA  1 
ATOM   1009  C C   . LYS A 1 127 ? -26.299 -17.313 38.166  1.00 32.94  ? 127 LYS A C   1 
ATOM   1010  O O   . LYS A 1 127 ? -25.738 -16.262 37.892  1.00 31.58  ? 127 LYS A O   1 
ATOM   1011  C CB  . LYS A 1 127 ? -27.738 -17.230 40.129  1.00 33.63  ? 127 LYS A CB  1 
ATOM   1012  C CG  . LYS A 1 127 ? -29.080 -16.975 40.782  1.00 34.48  ? 127 LYS A CG  1 
ATOM   1013  C CD  . LYS A 1 127 ? -28.938 -16.930 42.279  1.00 35.89  ? 127 LYS A CD  1 
ATOM   1014  C CE  . LYS A 1 127 ? -30.280 -16.887 42.960  1.00 38.15  ? 127 LYS A CE  1 
ATOM   1015  N NZ  . LYS A 1 127 ? -30.116 -16.632 44.407  1.00 43.04  ? 127 LYS A NZ  1 
ATOM   1016  N N   . ALA A 1 128 ? -25.684 -18.487 38.173  1.00 30.82  ? 128 ALA A N   1 
ATOM   1017  C CA  . ALA A 1 128 ? -24.303 -18.627 37.751  1.00 34.89  ? 128 ALA A CA  1 
ATOM   1018  C C   . ALA A 1 128 ? -24.145 -18.306 36.262  1.00 33.26  ? 128 ALA A C   1 
ATOM   1019  O O   . ALA A 1 128 ? -23.108 -17.794 35.841  1.00 34.51  ? 128 ALA A O   1 
ATOM   1020  C CB  . ALA A 1 128 ? -23.818 -20.028 38.085  1.00 34.26  ? 128 ALA A CB  1 
ATOM   1021  N N   . MET A 1 129 ? -25.153 -18.669 35.470  1.00 36.31  ? 129 MET A N   1 
ATOM   1022  C CA  . MET A 1 129 ? -25.197 -18.334 34.057  1.00 37.21  ? 129 MET A CA  1 
ATOM   1023  C C   . MET A 1 129 ? -25.403 -16.830 33.923  1.00 34.60  ? 129 MET A C   1 
ATOM   1024  O O   . MET A 1 129 ? -26.276 -16.275 34.582  1.00 33.39  ? 129 MET A O   1 
ATOM   1025  C CB  . MET A 1 129 ? -26.385 -18.998 33.356  1.00 42.60  ? 129 MET A CB  1 
ATOM   1026  C CG  . MET A 1 129 ? -26.302 -20.510 33.240  1.00 48.52  ? 129 MET A CG  1 
ATOM   1027  S SD  . MET A 1 129 ? -27.773 -21.167 32.386  1.00 54.42  ? 129 MET A SD  1 
ATOM   1028  C CE  . MET A 1 129 ? -27.144 -21.294 30.710  1.00 52.91  ? 129 MET A CE  1 
ATOM   1029  N N   . PRO A 1 130 ? -24.641 -16.138 33.050  1.00 34.40  ? 130 PRO A N   1 
ATOM   1030  C CA  . PRO A 1 130 ? -24.777 -14.697 32.879  1.00 38.63  ? 130 PRO A CA  1 
ATOM   1031  C C   . PRO A 1 130 ? -26.230 -14.306 32.641  1.00 38.49  ? 130 PRO A C   1 
ATOM   1032  O O   . PRO A 1 130 ? -26.944 -15.000 31.922  1.00 32.22  ? 130 PRO A O   1 
ATOM   1033  C CB  . PRO A 1 130 ? -23.929 -14.404 31.633  1.00 37.49  ? 130 PRO A CB  1 
ATOM   1034  C CG  . PRO A 1 130 ? -22.881 -15.474 31.659  1.00 37.81  ? 130 PRO A CG  1 
ATOM   1035  C CD  . PRO A 1 130 ? -23.598 -16.699 32.185  1.00 37.95  ? 130 PRO A CD  1 
ATOM   1036  N N   . ARG A 1 131 ? -26.645 -13.194 33.257  1.00 34.75  ? 131 ARG A N   1 
ATOM   1037  C CA  . ARG A 1 131 ? -28.049 -12.818 33.249  1.00 33.86  ? 131 ARG A CA  1 
ATOM   1038  C C   . ARG A 1 131 ? -28.490 -12.394 31.859  1.00 31.51  ? 131 ARG A C   1 
ATOM   1039  O O   . ARG A 1 131 ? -29.678 -12.375 31.600  1.00 29.66  ? 131 ARG A O   1 
ATOM   1040  C CB  . ARG A 1 131 ? -28.324 -11.683 34.232  1.00 33.32  ? 131 ARG A CB  1 
ATOM   1041  C CG  . ARG A 1 131 ? -29.794 -11.367 34.453  1.00 29.91  ? 131 ARG A CG  1 
ATOM   1042  C CD  . ARG A 1 131 ? -30.511 -12.523 35.078  1.00 28.84  ? 131 ARG A CD  1 
ATOM   1043  N NE  . ARG A 1 131 ? -29.842 -12.870 36.331  1.00 28.29  ? 131 ARG A NE  1 
ATOM   1044  C CZ  . ARG A 1 131 ? -30.335 -12.617 37.555  1.00 30.30  ? 131 ARG A CZ  1 
ATOM   1045  N NH1 . ARG A 1 131 ? -31.406 -11.845 37.726  1.00 26.67  ? 131 ARG A NH1 1 
ATOM   1046  N NH2 . ARG A 1 131 ? -29.748 -13.134 38.623  1.00 25.57  ? 131 ARG A NH2 1 
ATOM   1047  N N   . ASP A 1 132 ? -27.544 -12.094 30.962  1.00 38.79  ? 132 ASP A N   1 
ATOM   1048  C CA  . ASP A 1 132 ? -27.853 -11.685 29.580  1.00 41.82  ? 132 ASP A CA  1 
ATOM   1049  C C   . ASP A 1 132 ? -27.933 -12.882 28.613  1.00 38.09  ? 132 ASP A C   1 
ATOM   1050  O O   . ASP A 1 132 ? -28.021 -12.701 27.401  1.00 34.44  ? 132 ASP A O   1 
ATOM   1051  C CB  . ASP A 1 132 ? -26.810 -10.689 29.029  1.00 43.00  ? 132 ASP A CB  1 
ATOM   1052  C CG  . ASP A 1 132 ? -25.357 -11.156 29.107  1.00 46.41  ? 132 ASP A CG  1 
ATOM   1053  O OD1 . ASP A 1 132 ? -25.133 -12.319 29.465  1.00 46.88  ? 132 ASP A OD1 1 
ATOM   1054  O OD2 . ASP A 1 132 ? -24.447 -10.345 28.832  1.00 55.24  ? 132 ASP A OD2 1 
ATOM   1055  N N   . THR A 1 133 ? -27.842 -14.104 29.138  1.00 36.87  ? 133 THR A N   1 
ATOM   1056  C CA  . THR A 1 133 ? -28.093 -15.336 28.393  1.00 37.59  ? 133 THR A CA  1 
ATOM   1057  C C   . THR A 1 133 ? -29.530 -15.372 27.859  1.00 35.82  ? 133 THR A C   1 
ATOM   1058  O O   . THR A 1 133 ? -30.481 -14.944 28.516  1.00 36.56  ? 133 THR A O   1 
ATOM   1059  C CB  . THR A 1 133 ? -27.769 -16.534 29.293  1.00 34.30  ? 133 THR A CB  1 
ATOM   1060  O OG1 . THR A 1 133 ? -26.376 -16.434 29.600  1.00 39.95  ? 133 THR A OG1 1 
ATOM   1061  C CG2 . THR A 1 133 ? -28.066 -17.870 28.665  1.00 37.79  ? 133 THR A CG2 1 
ATOM   1062  N N   . HIS A 1 134 ? -29.667 -15.866 26.627  1.00 39.92  ? 134 HIS A N   1 
ATOM   1063  C CA  . HIS A 1 134 ? -30.976 -16.009 26.006  1.00 45.11  ? 134 HIS A CA  1 
ATOM   1064  C C   . HIS A 1 134 ? -31.843 -16.891 26.905  1.00 36.91  ? 134 HIS A C   1 
ATOM   1065  O O   . HIS A 1 134 ? -31.361 -17.865 27.444  1.00 37.17  ? 134 HIS A O   1 
ATOM   1066  C CB  . HIS A 1 134 ? -30.826 -16.535 24.568  1.00 47.81  ? 134 HIS A CB  1 
ATOM   1067  C CG  . HIS A 1 134 ? -32.105 -16.554 23.794  1.00 59.72  ? 134 HIS A CG  1 
ATOM   1068  N ND1 . HIS A 1 134 ? -33.074 -17.528 23.938  1.00 59.98  ? 134 HIS A ND1 1 
ATOM   1069  C CD2 . HIS A 1 134 ? -32.562 -15.659 22.864  1.00 64.54  ? 134 HIS A CD2 1 
ATOM   1070  C CE1 . HIS A 1 134 ? -34.100 -17.245 23.135  1.00 63.63  ? 134 HIS A CE1 1 
ATOM   1071  N NE2 . HIS A 1 134 ? -33.803 -16.084 22.462  1.00 65.87  ? 134 HIS A NE2 1 
ATOM   1072  N N   . PRO A 1 135 ? -33.129 -16.561 27.156  1.00 38.40  ? 135 PRO A N   1 
ATOM   1073  C CA  . PRO A 1 135 ? -33.960 -17.346 28.070  1.00 37.48  ? 135 PRO A CA  1 
ATOM   1074  C C   . PRO A 1 135 ? -34.130 -18.813 27.699  1.00 32.91  ? 135 PRO A C   1 
ATOM   1075  O O   . PRO A 1 135 ? -34.315 -19.635 28.582  1.00 28.45  ? 135 PRO A O   1 
ATOM   1076  C CB  . PRO A 1 135 ? -35.339 -16.658 28.022  1.00 37.04  ? 135 PRO A CB  1 
ATOM   1077  C CG  . PRO A 1 135 ? -35.299 -15.801 26.798  1.00 37.17  ? 135 PRO A CG  1 
ATOM   1078  C CD  . PRO A 1 135 ? -33.851 -15.389 26.646  1.00 35.03  ? 135 PRO A CD  1 
ATOM   1079  N N   . MET A 1 136 ? -34.103 -19.128 26.403  1.00 35.17  ? 136 MET A N   1 
ATOM   1080  C CA  . MET A 1 136 ? -34.236 -20.510 25.980  1.00 36.34  ? 136 MET A CA  1 
ATOM   1081  C C   . MET A 1 136 ? -32.980 -21.302 26.357  1.00 34.65  ? 136 MET A C   1 
ATOM   1082  O O   . MET A 1 136 ? -33.037 -22.515 26.561  1.00 30.09  ? 136 MET A O   1 
ATOM   1083  C CB  . MET A 1 136 ? -34.488 -20.610 24.476  1.00 39.89  ? 136 MET A CB  1 
ATOM   1084  C CG  . MET A 1 136 ? -35.973 -20.502 24.093  1.00 48.01  ? 136 MET A CG  1 
ATOM   1085  S SD  . MET A 1 136 ? -37.079 -21.878 24.648  1.00 48.80  ? 136 MET A SD  1 
ATOM   1086  C CE  . MET A 1 136 ? -36.155 -23.321 24.111  1.00 47.76  ? 136 MET A CE  1 
ATOM   1087  N N   . THR A 1 137 ? -31.837 -20.615 26.465  1.00 31.57  ? 137 THR A N   1 
ATOM   1088  C CA  . THR A 1 137 ? -30.622 -21.267 26.925  1.00 32.20  ? 137 THR A CA  1 
ATOM   1089  C C   . THR A 1 137 ? -30.797 -21.599 28.401  1.00 27.80  ? 137 THR A C   1 
ATOM   1090  O O   . THR A 1 137 ? -30.542 -22.706 28.834  1.00 27.19  ? 137 THR A O   1 
ATOM   1091  C CB  . THR A 1 137 ? -29.384 -20.413 26.614  1.00 31.14  ? 137 THR A CB  1 
ATOM   1092  O OG1 . THR A 1 137 ? -29.383 -20.135 25.213  1.00 26.14  ? 137 THR A OG1 1 
ATOM   1093  C CG2 . THR A 1 137 ? -28.081 -21.096 26.976  1.00 29.46  ? 137 THR A CG2 1 
ATOM   1094  N N   . MET A 1 138 ? -31.318 -20.640 29.153  1.00 29.45  ? 138 MET A N   1 
ATOM   1095  C CA  . MET A 1 138 ? -31.569 -20.835 30.569  1.00 30.42  ? 138 MET A CA  1 
ATOM   1096  C C   . MET A 1 138 ? -32.588 -21.941 30.799  1.00 27.58  ? 138 MET A C   1 
ATOM   1097  O O   . MET A 1 138 ? -32.394 -22.808 31.627  1.00 30.50  ? 138 MET A O   1 
ATOM   1098  C CB  . MET A 1 138 ? -32.055 -19.533 31.193  1.00 34.71  ? 138 MET A CB  1 
ATOM   1099  C CG  . MET A 1 138 ? -30.908 -18.601 31.447  1.00 38.77  ? 138 MET A CG  1 
ATOM   1100  S SD  . MET A 1 138 ? -31.500 -17.019 32.050  1.00 47.29  ? 138 MET A SD  1 
ATOM   1101  C CE  . MET A 1 138 ? -30.018 -16.295 32.766  1.00 50.94  ? 138 MET A CE  1 
ATOM   1102  N N   . PHE A 1 139 ? -33.667 -21.931 30.037  1.00 32.85  ? 139 PHE A N   1 
ATOM   1103  C CA  . PHE A 1 139 ? -34.700 -22.967 30.112  1.00 31.62  ? 139 PHE A CA  1 
ATOM   1104  C C   . PHE A 1 139 ? -34.122 -24.370 29.950  1.00 32.82  ? 139 PHE A C   1 
ATOM   1105  O O   . PHE A 1 139 ? -34.342 -25.232 30.805  1.00 33.87  ? 139 PHE A O   1 
ATOM   1106  C CB  . PHE A 1 139 ? -35.746 -22.725 29.025  1.00 28.32  ? 139 PHE A CB  1 
ATOM   1107  C CG  . PHE A 1 139 ? -37.031 -23.483 29.214  1.00 30.71  ? 139 PHE A CG  1 
ATOM   1108  C CD1 . PHE A 1 139 ? -37.742 -23.389 30.408  1.00 30.53  ? 139 PHE A CD1 1 
ATOM   1109  C CD2 . PHE A 1 139 ? -37.570 -24.238 28.179  1.00 31.73  ? 139 PHE A CD2 1 
ATOM   1110  C CE1 . PHE A 1 139 ? -38.942 -24.067 30.581  1.00 28.53  ? 139 PHE A CE1 1 
ATOM   1111  C CE2 . PHE A 1 139 ? -38.763 -24.919 28.363  1.00 32.64  ? 139 PHE A CE2 1 
ATOM   1112  C CZ  . PHE A 1 139 ? -39.456 -24.824 29.557  1.00 29.39  ? 139 PHE A CZ  1 
ATOM   1113  N N   . ALA A 1 140 ? -33.385 -24.579 28.840  1.00 34.90  ? 140 ALA A N   1 
ATOM   1114  C CA  . ALA A 1 140 ? -32.819 -25.870 28.483  1.00 31.86  ? 140 ALA A CA  1 
ATOM   1115  C C   . ALA A 1 140 ? -31.822 -26.332 29.555  1.00 33.70  ? 140 ALA A C   1 
ATOM   1116  O O   . ALA A 1 140 ? -31.788 -27.510 29.909  1.00 37.18  ? 140 ALA A O   1 
ATOM   1117  C CB  . ALA A 1 140 ? -32.172 -25.771 27.115  1.00 32.95  ? 140 ALA A CB  1 
ATOM   1118  N N   . ALA A 1 141 ? -31.020 -25.403 30.099  1.00 29.06  ? 141 ALA A N   1 
ATOM   1119  C CA  . ALA A 1 141 ? -30.064 -25.740 31.129  1.00 26.92  ? 141 ALA A CA  1 
ATOM   1120  C C   . ALA A 1 141 ? -30.731 -26.011 32.478  1.00 28.78  ? 141 ALA A C   1 
ATOM   1121  O O   . ALA A 1 141 ? -30.219 -26.776 33.278  1.00 35.90  ? 141 ALA A O   1 
ATOM   1122  C CB  . ALA A 1 141 ? -29.094 -24.617 31.237  1.00 31.94  ? 141 ALA A CB  1 
ATOM   1123  N N   . GLY A 1 142 ? -31.843 -25.357 32.795  1.00 30.75  ? 142 GLY A N   1 
ATOM   1124  C CA  . GLY A 1 142 ? -32.581 -25.685 34.009  1.00 32.92  ? 142 GLY A CA  1 
ATOM   1125  C C   . GLY A 1 142 ? -33.094 -27.124 33.989  1.00 33.31  ? 142 GLY A C   1 
ATOM   1126  O O   . GLY A 1 142 ? -33.090 -27.803 35.012  1.00 32.21  ? 142 GLY A O   1 
ATOM   1127  N N   . ILE A 1 143 ? -33.537 -27.573 32.806  1.00 35.05  ? 143 ILE A N   1 
ATOM   1128  C CA  . ILE A 1 143 ? -34.043 -28.923 32.618  1.00 34.53  ? 143 ILE A CA  1 
ATOM   1129  C C   . ILE A 1 143 ? -32.890 -29.902 32.778  1.00 32.94  ? 143 ILE A C   1 
ATOM   1130  O O   . ILE A 1 143 ? -32.959 -30.874 33.509  1.00 36.34  ? 143 ILE A O   1 
ATOM   1131  C CB  . ILE A 1 143 ? -34.649 -29.051 31.207  1.00 36.03  ? 143 ILE A CB  1 
ATOM   1132  C CG1 . ILE A 1 143 ? -35.864 -28.140 31.015  1.00 37.67  ? 143 ILE A CG1 1 
ATOM   1133  C CG2 . ILE A 1 143 ? -34.954 -30.506 30.882  1.00 39.03  ? 143 ILE A CG2 1 
ATOM   1134  C CD1 . ILE A 1 143 ? -36.258 -27.919 29.543  1.00 39.91  ? 143 ILE A CD1 1 
ATOM   1135  N N   . LEU A 1 144 ? -31.832 -29.628 32.028  1.00 34.33  ? 144 LEU A N   1 
ATOM   1136  C CA  . LEU A 1 144 ? -30.631 -30.447 32.001  1.00 39.41  ? 144 LEU A CA  1 
ATOM   1137  C C   . LEU A 1 144 ? -30.056 -30.684 33.404  1.00 38.62  ? 144 LEU A C   1 
ATOM   1138  O O   . LEU A 1 144 ? -29.688 -31.810 33.740  1.00 39.96  ? 144 LEU A O   1 
ATOM   1139  C CB  . LEU A 1 144 ? -29.617 -29.730 31.097  1.00 38.21  ? 144 LEU A CB  1 
ATOM   1140  C CG  . LEU A 1 144 ? -28.337 -30.499 30.816  1.00 36.51  ? 144 LEU A CG  1 
ATOM   1141  C CD1 . LEU A 1 144 ? -28.653 -31.928 30.411  1.00 38.16  ? 144 LEU A CD1 1 
ATOM   1142  C CD2 . LEU A 1 144 ? -27.538 -29.803 29.735  1.00 40.80  ? 144 LEU A CD2 1 
ATOM   1143  N N   . ALA A 1 145 ? -29.975 -29.619 34.210  1.00 40.50  ? 145 ALA A N   1 
ATOM   1144  C CA  . ALA A 1 145 ? -29.445 -29.685 35.573  1.00 42.46  ? 145 ALA A CA  1 
ATOM   1145  C C   . ALA A 1 145 ? -30.209 -30.695 36.422  1.00 44.08  ? 145 ALA A C   1 
ATOM   1146  O O   . ALA A 1 145 ? -29.617 -31.336 37.286  1.00 46.22  ? 145 ALA A O   1 
ATOM   1147  C CB  . ALA A 1 145 ? -29.503 -28.331 36.244  1.00 37.03  ? 145 ALA A CB  1 
ATOM   1148  N N   . MET A 1 146 ? -31.520 -30.825 36.152  1.00 41.85  ? 146 MET A N   1 
ATOM   1149  C CA  . MET A 1 146 ? -32.417 -31.664 36.936  1.00 39.82  ? 146 MET A CA  1 
ATOM   1150  C C   . MET A 1 146 ? -32.310 -33.148 36.575  1.00 32.56  ? 146 MET A C   1 
ATOM   1151  O O   . MET A 1 146 ? -32.994 -33.981 37.178  1.00 28.75  ? 146 MET A O   1 
ATOM   1152  C CB  . MET A 1 146 ? -33.860 -31.192 36.732  1.00 39.72  ? 146 MET A CB  1 
ATOM   1153  C CG  . MET A 1 146 ? -34.204 -30.017 37.585  1.00 42.26  ? 146 MET A CG  1 
ATOM   1154  S SD  . MET A 1 146 ? -35.910 -29.474 37.488  1.00 43.49  ? 146 MET A SD  1 
ATOM   1155  C CE  . MET A 1 146 ? -36.161 -29.028 35.771  1.00 31.72  ? 146 MET A CE  1 
ATOM   1156  N N   . GLN A 1 147 ? -31.472 -33.470 35.589  1.00 31.73  ? 147 GLN A N   1 
ATOM   1157  C CA  . GLN A 1 147 ? -31.212 -34.849 35.200  1.00 34.14  ? 147 GLN A CA  1 
ATOM   1158  C C   . GLN A 1 147 ? -30.676 -35.668 36.384  1.00 34.49  ? 147 GLN A C   1 
ATOM   1159  O O   . GLN A 1 147 ? -30.817 -36.895 36.438  1.00 31.82  ? 147 GLN A O   1 
ATOM   1160  C CB  . GLN A 1 147 ? -30.217 -34.836 34.032  1.00 35.67  ? 147 GLN A CB  1 
ATOM   1161  C CG  . GLN A 1 147 ? -29.980 -36.203 33.395  1.00 35.50  ? 147 GLN A CG  1 
ATOM   1162  C CD  . GLN A 1 147 ? -28.985 -37.044 34.158  1.00 31.93  ? 147 GLN A CD  1 
ATOM   1163  O OE1 . GLN A 1 147 ? -27.995 -36.532 34.685  1.00 33.45  ? 147 GLN A OE1 1 
ATOM   1164  N NE2 . GLN A 1 147 ? -29.269 -38.329 34.264  1.00 26.76  ? 147 GLN A NE2 1 
ATOM   1165  N N   . ARG A 1 148 ? -30.024 -34.980 37.321  1.00 32.88  ? 148 ARG A N   1 
ATOM   1166  C CA  . ARG A 1 148 ? -29.561 -35.555 38.577  1.00 36.79  ? 148 ARG A CA  1 
ATOM   1167  C C   . ARG A 1 148 ? -30.663 -36.322 39.311  1.00 36.51  ? 148 ARG A C   1 
ATOM   1168  O O   . ARG A 1 148 ? -30.348 -37.221 40.085  1.00 32.14  ? 148 ARG A O   1 
ATOM   1169  C CB  . ARG A 1 148 ? -29.057 -34.408 39.467  1.00 37.95  ? 148 ARG A CB  1 
ATOM   1170  C CG  . ARG A 1 148 ? -28.464 -34.839 40.797  1.00 41.14  ? 148 ARG A CG  1 
ATOM   1171  C CD  . ARG A 1 148 ? -28.041 -33.609 41.570  1.00 41.89  ? 148 ARG A CD  1 
ATOM   1172  N NE  . ARG A 1 148 ? -27.692 -33.890 42.956  1.00 47.85  ? 148 ARG A NE  1 
ATOM   1173  C CZ  . ARG A 1 148 ? -28.546 -34.107 43.959  1.00 44.57  ? 148 ARG A CZ  1 
ATOM   1174  N NH1 . ARG A 1 148 ? -29.856 -34.103 43.765  1.00 39.20  ? 148 ARG A NH1 1 
ATOM   1175  N NH2 . ARG A 1 148 ? -28.055 -34.342 45.170  1.00 45.55  ? 148 ARG A NH2 1 
ATOM   1176  N N   . GLU A 1 149 ? -31.939 -35.937 39.105  1.00 35.87  ? 149 GLU A N   1 
ATOM   1177  C CA  . GLU A 1 149 ? -33.067 -36.512 39.832  1.00 42.06  ? 149 GLU A CA  1 
ATOM   1178  C C   . GLU A 1 149 ? -33.789 -37.599 39.023  1.00 40.08  ? 149 GLU A C   1 
ATOM   1179  O O   . GLU A 1 149 ? -34.889 -38.018 39.394  1.00 37.19  ? 149 GLU A O   1 
ATOM   1180  C CB  . GLU A 1 149 ? -34.117 -35.437 40.134  1.00 44.35  ? 149 GLU A CB  1 
ATOM   1181  C CG  . GLU A 1 149 ? -33.554 -34.115 40.632  1.00 48.31  ? 149 GLU A CG  1 
ATOM   1182  C CD  . GLU A 1 149 ? -32.678 -34.205 41.871  1.00 50.11  ? 149 GLU A CD  1 
ATOM   1183  O OE1 . GLU A 1 149 ? -32.752 -35.225 42.570  1.00 51.53  ? 149 GLU A OE1 1 
ATOM   1184  O OE2 . GLU A 1 149 ? -31.915 -33.250 42.131  1.00 58.95  ? 149 GLU A OE2 1 
ATOM   1185  N N   . SER A 1 150 ? -33.215 -38.000 37.885  1.00 37.31  ? 150 SER A N   1 
ATOM   1186  C CA  . SER A 1 150 ? -33.904 -38.878 36.959  1.00 40.43  ? 150 SER A CA  1 
ATOM   1187  C C   . SER A 1 150 ? -34.089 -40.252 37.592  1.00 41.91  ? 150 SER A C   1 
ATOM   1188  O O   . SER A 1 150 ? -33.133 -40.877 38.069  1.00 45.05  ? 150 SER A O   1 
ATOM   1189  C CB  . SER A 1 150 ? -33.174 -38.984 35.635  1.00 40.54  ? 150 SER A CB  1 
ATOM   1190  O OG  . SER A 1 150 ? -33.775 -39.973 34.798  1.00 39.92  ? 150 SER A OG  1 
ATOM   1191  N N   . LYS A 1 151 ? -35.343 -40.707 37.585  1.00 45.51  ? 151 LYS A N   1 
ATOM   1192  C CA  . LYS A 1 151 ? -35.713 -42.008 38.127  1.00 43.62  ? 151 LYS A CA  1 
ATOM   1193  C C   . LYS A 1 151 ? -35.371 -43.090 37.124  1.00 38.53  ? 151 LYS A C   1 
ATOM   1194  O O   . LYS A 1 151 ? -34.864 -44.144 37.485  1.00 43.40  ? 151 LYS A O   1 
ATOM   1195  C CB  . LYS A 1 151 ? -37.202 -42.004 38.464  1.00 47.65  ? 151 LYS A CB  1 
ATOM   1196  C CG  . LYS A 1 151 ? -37.467 -41.476 39.857  1.00 48.69  ? 151 LYS A CG  1 
ATOM   1197  C CD  . LYS A 1 151 ? -38.572 -40.506 39.940  1.00 52.41  ? 151 LYS A CD  1 
ATOM   1198  C CE  . LYS A 1 151 ? -38.534 -39.843 41.299  1.00 60.68  ? 151 LYS A CE  1 
ATOM   1199  N NZ  . LYS A 1 151 ? -39.659 -38.895 41.429  1.00 68.77  ? 151 LYS A NZ  1 
ATOM   1200  N N   . PHE A 1 152 ? -35.636 -42.775 35.866  1.00 37.19  ? 152 PHE A N   1 
ATOM   1201  C CA  . PHE A 1 152 ? -35.226 -43.628 34.773  1.00 39.95  ? 152 PHE A CA  1 
ATOM   1202  C C   . PHE A 1 152 ? -33.724 -43.893 34.816  1.00 36.86  ? 152 PHE A C   1 
ATOM   1203  O O   . PHE A 1 152 ? -33.308 -45.034 34.686  1.00 40.37  ? 152 PHE A O   1 
ATOM   1204  C CB  . PHE A 1 152 ? -35.615 -43.004 33.439  1.00 41.99  ? 152 PHE A CB  1 
ATOM   1205  C CG  . PHE A 1 152 ? -35.510 -43.971 32.295  1.00 51.14  ? 152 PHE A CG  1 
ATOM   1206  C CD1 . PHE A 1 152 ? -36.570 -44.811 31.981  1.00 53.11  ? 152 PHE A CD1 1 
ATOM   1207  C CD2 . PHE A 1 152 ? -34.327 -44.077 31.584  1.00 55.00  ? 152 PHE A CD2 1 
ATOM   1208  C CE1 . PHE A 1 152 ? -36.464 -45.707 30.935  1.00 57.70  ? 152 PHE A CE1 1 
ATOM   1209  C CE2 . PHE A 1 152 ? -34.230 -44.965 30.530  1.00 61.43  ? 152 PHE A CE2 1 
ATOM   1210  C CZ  . PHE A 1 152 ? -35.298 -45.782 30.211  1.00 64.70  ? 152 PHE A CZ  1 
ATOM   1211  N N   . ALA A 1 153 ? -32.911 -42.844 34.969  1.00 37.71  ? 153 ALA A N   1 
ATOM   1212  C CA  . ALA A 1 153 ? -31.468 -43.014 34.988  1.00 38.53  ? 153 ALA A CA  1 
ATOM   1213  C C   . ALA A 1 153 ? -31.060 -43.930 36.149  1.00 43.17  ? 153 ALA A C   1 
ATOM   1214  O O   . ALA A 1 153 ? -30.347 -44.917 35.939  1.00 52.28  ? 153 ALA A O   1 
ATOM   1215  C CB  . ALA A 1 153 ? -30.795 -41.669 35.037  1.00 39.04  ? 153 ALA A CB  1 
ATOM   1216  N N   . ALA A 1 154 ? -31.600 -43.646 37.345  1.00 47.82  ? 154 ALA A N   1 
ATOM   1217  C CA  . ALA A 1 154 ? -31.375 -44.450 38.549  1.00 51.59  ? 154 ALA A CA  1 
ATOM   1218  C C   . ALA A 1 154 ? -31.727 -45.922 38.316  1.00 50.23  ? 154 ALA A C   1 
ATOM   1219  O O   . ALA A 1 154 ? -30.949 -46.816 38.691  1.00 44.49  ? 154 ALA A O   1 
ATOM   1220  C CB  . ALA A 1 154 ? -32.196 -43.904 39.708  1.00 52.12  ? 154 ALA A CB  1 
ATOM   1221  N N   . TYR A 1 155 ? -32.924 -46.133 37.719  1.00 46.01  ? 155 TYR A N   1 
ATOM   1222  C CA  . TYR A 1 155 ? -33.463 -47.452 37.392  1.00 46.05  ? 155 TYR A CA  1 
ATOM   1223  C C   . TYR A 1 155 ? -32.468 -48.213 36.521  1.00 47.18  ? 155 TYR A C   1 
ATOM   1224  O O   . TYR A 1 155 ? -32.031 -49.300 36.898  1.00 41.18  ? 155 TYR A O   1 
ATOM   1225  C CB  . TYR A 1 155 ? -34.832 -47.270 36.740  1.00 42.64  ? 155 TYR A CB  1 
ATOM   1226  C CG  . TYR A 1 155 ? -35.472 -48.408 35.981  1.00 43.49  ? 155 TYR A CG  1 
ATOM   1227  C CD1 . TYR A 1 155 ? -36.134 -49.441 36.632  1.00 43.77  ? 155 TYR A CD1 1 
ATOM   1228  C CD2 . TYR A 1 155 ? -35.544 -48.369 34.592  1.00 43.77  ? 155 TYR A CD2 1 
ATOM   1229  C CE1 . TYR A 1 155 ? -36.811 -50.427 35.920  1.00 45.84  ? 155 TYR A CE1 1 
ATOM   1230  C CE2 . TYR A 1 155 ? -36.209 -49.351 33.866  1.00 49.14  ? 155 TYR A CE2 1 
ATOM   1231  C CZ  . TYR A 1 155 ? -36.854 -50.387 34.530  1.00 49.29  ? 155 TYR A CZ  1 
ATOM   1232  O OH  . TYR A 1 155 ? -37.525 -51.353 33.798  1.00 50.97  ? 155 TYR A OH  1 
ATOM   1233  N N   . TYR A 1 156 ? -32.061 -47.594 35.404  1.00 42.57  ? 156 TYR A N   1 
ATOM   1234  C CA  . TYR A 1 156 ? -31.156 -48.242 34.487  1.00 43.65  ? 156 TYR A CA  1 
ATOM   1235  C C   . TYR A 1 156 ? -29.817 -48.516 35.163  1.00 46.30  ? 156 TYR A C   1 
ATOM   1236  O O   . TYR A 1 156 ? -29.325 -49.641 35.073  1.00 39.19  ? 156 TYR A O   1 
ATOM   1237  C CB  . TYR A 1 156 ? -30.967 -47.402 33.233  1.00 47.10  ? 156 TYR A CB  1 
ATOM   1238  C CG  . TYR A 1 156 ? -30.191 -48.146 32.187  1.00 50.27  ? 156 TYR A CG  1 
ATOM   1239  C CD1 . TYR A 1 156 ? -28.836 -48.394 32.349  1.00 52.38  ? 156 TYR A CD1 1 
ATOM   1240  C CD2 . TYR A 1 156 ? -30.833 -48.679 31.079  1.00 57.40  ? 156 TYR A CD2 1 
ATOM   1241  C CE1 . TYR A 1 156 ? -28.119 -49.111 31.405  1.00 61.69  ? 156 TYR A CE1 1 
ATOM   1242  C CE2 . TYR A 1 156 ? -30.130 -49.401 30.125  1.00 61.19  ? 156 TYR A CE2 1 
ATOM   1243  C CZ  . TYR A 1 156 ? -28.766 -49.601 30.279  1.00 64.02  ? 156 TYR A CZ  1 
ATOM   1244  O OH  . TYR A 1 156 ? -28.073 -50.302 29.322  1.00 68.01  ? 156 TYR A OH  1 
ATOM   1245  N N   . ASN A 1 157 ? -29.243 -47.500 35.838  1.00 50.84  ? 157 ASN A N   1 
ATOM   1246  C CA  . ASN A 1 157 ? -27.885 -47.584 36.366  1.00 50.46  ? 157 ASN A CA  1 
ATOM   1247  C C   . ASN A 1 157 ? -27.790 -48.609 37.480  1.00 46.88  ? 157 ASN A C   1 
ATOM   1248  O O   . ASN A 1 157 ? -26.699 -49.151 37.679  1.00 48.56  ? 157 ASN A O   1 
ATOM   1249  C CB  . ASN A 1 157 ? -27.351 -46.247 36.906  1.00 55.83  ? 157 ASN A CB  1 
ATOM   1250  C CG  . ASN A 1 157 ? -27.115 -45.215 35.818  1.00 65.94  ? 157 ASN A CG  1 
ATOM   1251  O OD1 . ASN A 1 157 ? -26.882 -45.565 34.656  1.00 59.98  ? 157 ASN A OD1 1 
ATOM   1252  N ND2 . ASN A 1 157 ? -27.161 -43.942 36.190  1.00 71.09  ? 157 ASN A ND2 1 
ATOM   1253  N N   . ALA A 1 158 ? -28.910 -48.819 38.201  1.00 47.57  ? 158 ALA A N   1 
ATOM   1254  C CA  . ALA A 1 158 ? -29.018 -49.859 39.223  1.00 47.30  ? 158 ALA A CA  1 
ATOM   1255  C C   . ALA A 1 158 ? -29.236 -51.271 38.639  1.00 52.01  ? 158 ALA A C   1 
ATOM   1256  O O   . ALA A 1 158 ? -29.503 -52.210 39.387  1.00 48.01  ? 158 ALA A O   1 
ATOM   1257  C CB  . ALA A 1 158 ? -30.149 -49.512 40.147  1.00 46.01  ? 158 ALA A CB  1 
ATOM   1258  N N   . GLY A 1 159 ? -29.161 -51.442 37.309  1.00 51.37  ? 159 GLY A N   1 
ATOM   1259  C CA  . GLY A 1 159 ? -29.260 -52.753 36.683  1.00 52.08  ? 159 GLY A CA  1 
ATOM   1260  C C   . GLY A 1 159 ? -30.671 -53.359 36.658  1.00 51.28  ? 159 GLY A C   1 
ATOM   1261  O O   . GLY A 1 159 ? -30.798 -54.563 36.459  1.00 56.33  ? 159 GLY A O   1 
ATOM   1262  N N   . LYS A 1 160 ? -31.727 -52.546 36.818  1.00 50.73  ? 160 LYS A N   1 
ATOM   1263  C CA  . LYS A 1 160 ? -33.099 -53.035 36.918  1.00 52.59  ? 160 LYS A CA  1 
ATOM   1264  C C   . LYS A 1 160 ? -33.870 -52.854 35.615  1.00 53.44  ? 160 LYS A C   1 
ATOM   1265  O O   . LYS A 1 160 ? -35.084 -53.067 35.608  1.00 44.85  ? 160 LYS A O   1 
ATOM   1266  C CB  . LYS A 1 160 ? -33.898 -52.287 37.990  1.00 54.66  ? 160 LYS A CB  1 
ATOM   1267  C CG  . LYS A 1 160 ? -33.142 -52.052 39.290  1.00 65.32  ? 160 LYS A CG  1 
ATOM   1268  C CD  . LYS A 1 160 ? -33.999 -51.547 40.426  1.00 72.12  ? 160 LYS A CD  1 
ATOM   1269  C CE  . LYS A 1 160 ? -33.165 -50.857 41.484  1.00 85.22  ? 160 LYS A CE  1 
ATOM   1270  N NZ  . LYS A 1 160 ? -34.009 -50.349 42.590  1.00 95.37  ? 160 LYS A NZ  1 
ATOM   1271  N N   . PHE A 1 161 ? -33.177 -52.467 34.527  1.00 54.89  ? 161 PHE A N   1 
ATOM   1272  C CA  . PHE A 1 161 ? -33.837 -52.269 33.245  1.00 50.09  ? 161 PHE A CA  1 
ATOM   1273  C C   . PHE A 1 161 ? -34.522 -53.559 32.806  1.00 50.39  ? 161 PHE A C   1 
ATOM   1274  O O   . PHE A 1 161 ? -33.941 -54.633 32.872  1.00 50.16  ? 161 PHE A O   1 
ATOM   1275  C CB  . PHE A 1 161 ? -32.888 -51.825 32.132  1.00 51.28  ? 161 PHE A CB  1 
ATOM   1276  C CG  . PHE A 1 161 ? -33.623 -51.555 30.845  1.00 59.72  ? 161 PHE A CG  1 
ATOM   1277  C CD1 . PHE A 1 161 ? -34.406 -50.414 30.704  1.00 59.15  ? 161 PHE A CD1 1 
ATOM   1278  C CD2 . PHE A 1 161 ? -33.637 -52.499 29.820  1.00 66.85  ? 161 PHE A CD2 1 
ATOM   1279  C CE1 . PHE A 1 161 ? -35.115 -50.179 29.532  1.00 56.76  ? 161 PHE A CE1 1 
ATOM   1280  C CE2 . PHE A 1 161 ? -34.359 -52.271 28.655  1.00 63.37  ? 161 PHE A CE2 1 
ATOM   1281  C CZ  . PHE A 1 161 ? -35.084 -51.105 28.509  1.00 62.40  ? 161 PHE A CZ  1 
ATOM   1282  N N   . ASN A 1 162 ? -35.743 -53.419 32.297  1.00 55.33  ? 162 ASN A N   1 
ATOM   1283  C CA  . ASN A 1 162 ? -36.592 -54.533 31.941  1.00 54.29  ? 162 ASN A CA  1 
ATOM   1284  C C   . ASN A 1 162 ? -37.482 -54.020 30.825  1.00 62.09  ? 162 ASN A C   1 
ATOM   1285  O O   . ASN A 1 162 ? -38.182 -53.035 31.040  1.00 69.39  ? 162 ASN A O   1 
ATOM   1286  C CB  . ASN A 1 162 ? -37.392 -54.964 33.172  1.00 57.88  ? 162 ASN A CB  1 
ATOM   1287  C CG  . ASN A 1 162 ? -38.413 -56.046 32.901  1.00 58.89  ? 162 ASN A CG  1 
ATOM   1288  O OD1 . ASN A 1 162 ? -39.428 -55.827 32.239  1.00 54.61  ? 162 ASN A OD1 1 
ATOM   1289  N ND2 . ASN A 1 162 ? -38.160 -57.215 33.451  1.00 59.98  ? 162 ASN A ND2 1 
ATOM   1290  N N   . LYS A 1 163 ? -37.465 -54.660 29.652  1.00 66.27  ? 163 LYS A N   1 
ATOM   1291  C CA  . LYS A 1 163 ? -38.202 -54.125 28.514  1.00 69.73  ? 163 LYS A CA  1 
ATOM   1292  C C   . LYS A 1 163 ? -39.630 -53.722 28.925  1.00 62.07  ? 163 LYS A C   1 
ATOM   1293  O O   . LYS A 1 163 ? -40.154 -52.753 28.383  1.00 59.31  ? 163 LYS A O   1 
ATOM   1294  C CB  . LYS A 1 163 ? -38.185 -55.113 27.334  1.00 82.66  ? 163 LYS A CB  1 
ATOM   1295  C CG  . LYS A 1 163 ? -38.380 -54.534 25.926  1.00 94.68  ? 163 LYS A CG  1 
ATOM   1296  C CD  . LYS A 1 163 ? -39.734 -54.847 25.232  1.00 104.53 ? 163 LYS A CD  1 
ATOM   1297  C CE  . LYS A 1 163 ? -40.906 -53.974 25.660  1.00 101.33 ? 163 LYS A CE  1 
ATOM   1298  N NZ  . LYS A 1 163 ? -42.151 -54.254 24.899  1.00 85.79  ? 163 LYS A NZ  1 
ATOM   1299  N N   . ASN A 1 164 ? -40.261 -54.411 29.894  1.00 62.65  ? 164 ASN A N   1 
ATOM   1300  C CA  . ASN A 1 164 ? -41.708 -54.309 30.081  1.00 67.92  ? 164 ASN A CA  1 
ATOM   1301  C C   . ASN A 1 164 ? -42.123 -53.162 30.993  1.00 65.01  ? 164 ASN A C   1 
ATOM   1302  O O   . ASN A 1 164 ? -43.173 -52.566 30.755  1.00 64.91  ? 164 ASN A O   1 
ATOM   1303  C CB  . ASN A 1 164 ? -42.319 -55.608 30.605  1.00 70.98  ? 164 ASN A CB  1 
ATOM   1304  C CG  . ASN A 1 164 ? -42.097 -56.742 29.625  1.00 73.75  ? 164 ASN A CG  1 
ATOM   1305  O OD1 . ASN A 1 164 ? -42.467 -56.653 28.451  1.00 65.84  ? 164 ASN A OD1 1 
ATOM   1306  N ND2 . ASN A 1 164 ? -41.422 -57.781 30.080  1.00 78.71  ? 164 ASN A ND2 1 
ATOM   1307  N N   . THR A 1 165 ? -41.295 -52.849 32.001  1.00 67.82  ? 165 THR A N   1 
ATOM   1308  C CA  . THR A 1 165 ? -41.638 -51.897 33.054  1.00 62.10  ? 165 THR A CA  1 
ATOM   1309  C C   . THR A 1 165 ? -40.869 -50.576 32.903  1.00 60.25  ? 165 THR A C   1 
ATOM   1310  O O   . THR A 1 165 ? -40.991 -49.701 33.754  1.00 58.94  ? 165 THR A O   1 
ATOM   1311  C CB  . THR A 1 165 ? -41.365 -52.542 34.417  1.00 62.58  ? 165 THR A CB  1 
ATOM   1312  O OG1 . THR A 1 165 ? -39.955 -52.782 34.534  1.00 64.24  ? 165 THR A OG1 1 
ATOM   1313  C CG2 . THR A 1 165 ? -42.138 -53.831 34.600  1.00 60.68  ? 165 THR A CG2 1 
ATOM   1314  N N   . ALA A 1 166 ? -40.108 -50.420 31.811  1.00 51.71  ? 166 ALA A N   1 
ATOM   1315  C CA  . ALA A 1 166 ? -39.294 -49.235 31.572  1.00 49.37  ? 166 ALA A CA  1 
ATOM   1316  C C   . ALA A 1 166 ? -40.141 -47.954 31.537  1.00 47.44  ? 166 ALA A C   1 
ATOM   1317  O O   . ALA A 1 166 ? -39.668 -46.878 31.914  1.00 46.57  ? 166 ALA A O   1 
ATOM   1318  C CB  . ALA A 1 166 ? -38.497 -49.409 30.289  1.00 47.68  ? 166 ALA A CB  1 
ATOM   1319  N N   . TRP A 1 167 ? -41.394 -48.051 31.087  1.00 45.13  ? 167 TRP A N   1 
ATOM   1320  C CA  . TRP A 1 167 ? -42.213 -46.863 30.946  1.00 41.63  ? 167 TRP A CA  1 
ATOM   1321  C C   . TRP A 1 167 ? -42.565 -46.321 32.326  1.00 43.07  ? 167 TRP A C   1 
ATOM   1322  O O   . TRP A 1 167 ? -42.942 -45.153 32.452  1.00 45.81  ? 167 TRP A O   1 
ATOM   1323  C CB  . TRP A 1 167 ? -43.478 -47.123 30.120  1.00 37.68  ? 167 TRP A CB  1 
ATOM   1324  C CG  . TRP A 1 167 ? -44.419 -48.059 30.802  1.00 35.83  ? 167 TRP A CG  1 
ATOM   1325  C CD1 . TRP A 1 167 ? -44.384 -49.411 30.704  1.00 36.63  ? 167 TRP A CD1 1 
ATOM   1326  C CD2 . TRP A 1 167 ? -45.460 -47.748 31.755  1.00 35.13  ? 167 TRP A CD2 1 
ATOM   1327  N NE1 . TRP A 1 167 ? -45.361 -49.957 31.484  1.00 37.45  ? 167 TRP A NE1 1 
ATOM   1328  C CE2 . TRP A 1 167 ? -46.027 -48.972 32.164  1.00 35.51  ? 167 TRP A CE2 1 
ATOM   1329  C CE3 . TRP A 1 167 ? -45.997 -46.571 32.296  1.00 35.79  ? 167 TRP A CE3 1 
ATOM   1330  C CZ2 . TRP A 1 167 ? -47.088 -49.056 33.078  1.00 31.91  ? 167 TRP A CZ2 1 
ATOM   1331  C CZ3 . TRP A 1 167 ? -47.049 -46.657 33.187  1.00 34.11  ? 167 TRP A CZ3 1 
ATOM   1332  C CH2 . TRP A 1 167 ? -47.587 -47.880 33.577  1.00 29.29  ? 167 TRP A CH2 1 
ATOM   1333  N N   . GLU A 1 168 ? -42.466 -47.168 33.355  1.00 42.91  ? 168 GLU A N   1 
ATOM   1334  C CA  . GLU A 1 168 ? -42.945 -46.759 34.668  1.00 51.28  ? 168 GLU A CA  1 
ATOM   1335  C C   . GLU A 1 168 ? -42.102 -45.612 35.253  1.00 47.06  ? 168 GLU A C   1 
ATOM   1336  O O   . GLU A 1 168 ? -42.638 -44.532 35.500  1.00 46.45  ? 168 GLU A O   1 
ATOM   1337  C CB  . GLU A 1 168 ? -43.064 -47.992 35.555  1.00 57.98  ? 168 GLU A CB  1 
ATOM   1338  C CG  . GLU A 1 168 ? -44.071 -48.984 34.991  1.00 64.57  ? 168 GLU A CG  1 
ATOM   1339  C CD  . GLU A 1 168 ? -44.544 -50.043 35.972  1.00 67.42  ? 168 GLU A CD  1 
ATOM   1340  O OE1 . GLU A 1 168 ? -44.345 -51.258 35.697  1.00 72.74  ? 168 GLU A OE1 1 
ATOM   1341  O OE2 . GLU A 1 168 ? -45.129 -49.643 37.001  1.00 70.55  ? 168 GLU A OE2 1 
ATOM   1342  N N   . PRO A 1 169 ? -40.778 -45.766 35.482  1.00 41.45  ? 169 PRO A N   1 
ATOM   1343  C CA  . PRO A 1 169 ? -39.918 -44.635 35.848  1.00 42.62  ? 169 PRO A CA  1 
ATOM   1344  C C   . PRO A 1 169 ? -39.947 -43.476 34.858  1.00 40.93  ? 169 PRO A C   1 
ATOM   1345  O O   . PRO A 1 169 ? -39.898 -42.320 35.256  1.00 39.57  ? 169 PRO A O   1 
ATOM   1346  C CB  . PRO A 1 169 ? -38.491 -45.198 35.832  1.00 44.51  ? 169 PRO A CB  1 
ATOM   1347  C CG  . PRO A 1 169 ? -38.611 -46.525 35.095  1.00 41.62  ? 169 PRO A CG  1 
ATOM   1348  C CD  . PRO A 1 169 ? -40.018 -47.014 35.380  1.00 40.70  ? 169 PRO A CD  1 
ATOM   1349  N N   . MET A 1 170 ? -40.048 -43.789 33.564  1.00 41.30  ? 170 MET A N   1 
ATOM   1350  C CA  . MET A 1 170 ? -40.103 -42.757 32.538  1.00 38.83  ? 170 MET A CA  1 
ATOM   1351  C C   . MET A 1 170 ? -41.353 -41.906 32.746  1.00 32.34  ? 170 MET A C   1 
ATOM   1352  O O   . MET A 1 170 ? -41.292 -40.698 32.640  1.00 34.70  ? 170 MET A O   1 
ATOM   1353  C CB  . MET A 1 170 ? -40.046 -43.391 31.138  1.00 43.93  ? 170 MET A CB  1 
ATOM   1354  C CG  . MET A 1 170 ? -40.202 -42.429 29.965  1.00 47.04  ? 170 MET A CG  1 
ATOM   1355  S SD  . MET A 1 170 ? -38.916 -41.130 29.839  1.00 57.85  ? 170 MET A SD  1 
ATOM   1356  C CE  . MET A 1 170 ? -37.545 -42.041 29.127  1.00 53.60  ? 170 MET A CE  1 
ATOM   1357  N N   . PHE A 1 171 ? -42.470 -42.516 33.137  1.00 35.98  ? 171 PHE A N   1 
ATOM   1358  C CA  . PHE A 1 171 ? -43.695 -41.792 33.486  1.00 31.79  ? 171 PHE A CA  1 
ATOM   1359  C C   . PHE A 1 171 ? -43.533 -40.928 34.742  1.00 31.99  ? 171 PHE A C   1 
ATOM   1360  O O   . PHE A 1 171 ? -44.179 -39.886 34.862  1.00 29.70  ? 171 PHE A O   1 
ATOM   1361  C CB  . PHE A 1 171 ? -44.845 -42.768 33.720  1.00 31.95  ? 171 PHE A CB  1 
ATOM   1362  C CG  . PHE A 1 171 ? -46.074 -42.175 34.358  1.00 31.56  ? 171 PHE A CG  1 
ATOM   1363  C CD1 . PHE A 1 171 ? -47.036 -41.511 33.602  1.00 35.32  ? 171 PHE A CD1 1 
ATOM   1364  C CD2 . PHE A 1 171 ? -46.282 -42.296 35.727  1.00 32.25  ? 171 PHE A CD2 1 
ATOM   1365  C CE1 . PHE A 1 171 ? -48.185 -40.995 34.210  1.00 37.91  ? 171 PHE A CE1 1 
ATOM   1366  C CE2 . PHE A 1 171 ? -47.415 -41.760 36.338  1.00 33.63  ? 171 PHE A CE2 1 
ATOM   1367  C CZ  . PHE A 1 171 ? -48.369 -41.112 35.582  1.00 35.66  ? 171 PHE A CZ  1 
ATOM   1368  N N   . GLU A 1 172 ? -42.724 -41.367 35.713  1.00 33.81  ? 172 GLU A N   1 
ATOM   1369  C CA  . GLU A 1 172 ? -42.522 -40.590 36.926  1.00 40.43  ? 172 GLU A CA  1 
ATOM   1370  C C   . GLU A 1 172 ? -41.697 -39.350 36.616  1.00 39.11  ? 172 GLU A C   1 
ATOM   1371  O O   . GLU A 1 172 ? -42.030 -38.266 37.088  1.00 35.48  ? 172 GLU A O   1 
ATOM   1372  C CB  . GLU A 1 172 ? -41.855 -41.423 38.019  1.00 49.24  ? 172 GLU A CB  1 
ATOM   1373  C CG  . GLU A 1 172 ? -42.770 -42.508 38.582  1.00 59.09  ? 172 GLU A CG  1 
ATOM   1374  C CD  . GLU A 1 172 ? -44.089 -42.039 39.197  1.00 69.38  ? 172 GLU A CD  1 
ATOM   1375  O OE1 . GLU A 1 172 ? -44.084 -40.970 39.828  1.00 71.86  ? 172 GLU A OE1 1 
ATOM   1376  O OE2 . GLU A 1 172 ? -45.114 -42.760 39.084  1.00 68.33  ? 172 GLU A OE2 1 
ATOM   1377  N N   . ASP A 1 173 ? -40.646 -39.526 35.800  1.00 37.01  ? 173 ASP A N   1 
ATOM   1378  C CA  . ASP A 1 173 ? -39.834 -38.428 35.300  1.00 32.36  ? 173 ASP A CA  1 
ATOM   1379  C C   . ASP A 1 173 ? -40.712 -37.445 34.554  1.00 32.77  ? 173 ASP A C   1 
ATOM   1380  O O   . ASP A 1 173 ? -40.538 -36.237 34.727  1.00 41.05  ? 173 ASP A O   1 
ATOM   1381  C CB  . ASP A 1 173 ? -38.677 -38.955 34.448  1.00 36.00  ? 173 ASP A CB  1 
ATOM   1382  C CG  . ASP A 1 173 ? -37.533 -39.462 35.327  1.00 42.39  ? 173 ASP A CG  1 
ATOM   1383  O OD1 . ASP A 1 173 ? -37.596 -39.223 36.593  1.00 39.66  ? 173 ASP A OD1 1 
ATOM   1384  O OD2 . ASP A 1 173 ? -36.572 -40.077 34.768  1.00 39.22  ? 173 ASP A OD2 1 
ATOM   1385  N N   . ALA A 1 174 ? -41.659 -37.964 33.765  1.00 30.58  ? 174 ALA A N   1 
ATOM   1386  C CA  . ALA A 1 174 ? -42.569 -37.137 32.982  1.00 32.87  ? 174 ALA A CA  1 
ATOM   1387  C C   . ALA A 1 174 ? -43.472 -36.330 33.913  1.00 34.64  ? 174 ALA A C   1 
ATOM   1388  O O   . ALA A 1 174 ? -43.652 -35.133 33.698  1.00 36.10  ? 174 ALA A O   1 
ATOM   1389  C CB  . ALA A 1 174 ? -43.376 -37.969 32.011  1.00 31.50  ? 174 ALA A CB  1 
ATOM   1390  N N   . MET A 1 175 ? -43.988 -36.947 34.979  1.00 35.52  ? 175 MET A N   1 
ATOM   1391  C CA  . MET A 1 175 ? -44.860 -36.224 35.894  1.00 41.14  ? 175 MET A CA  1 
ATOM   1392  C C   . MET A 1 175 ? -44.094 -35.108 36.612  1.00 44.88  ? 175 MET A C   1 
ATOM   1393  O O   . MET A 1 175 ? -44.597 -33.982 36.758  1.00 48.39  ? 175 MET A O   1 
ATOM   1394  C CB  . MET A 1 175 ? -45.454 -37.182 36.926  1.00 46.30  ? 175 MET A CB  1 
ATOM   1395  C CG  . MET A 1 175 ? -46.499 -38.098 36.322  1.00 54.34  ? 175 MET A CG  1 
ATOM   1396  S SD  . MET A 1 175 ? -48.032 -37.247 35.787  1.00 61.97  ? 175 MET A SD  1 
ATOM   1397  C CE  . MET A 1 175 ? -48.697 -36.729 37.375  1.00 56.58  ? 175 MET A CE  1 
ATOM   1398  N N   . ASP A 1 176 ? -42.863 -35.435 37.019  1.00 37.31  ? 176 ASP A N   1 
ATOM   1399  C CA  . ASP A 1 176 ? -42.000 -34.530 37.755  1.00 36.88  ? 176 ASP A CA  1 
ATOM   1400  C C   . ASP A 1 176 ? -41.583 -33.362 36.869  1.00 35.55  ? 176 ASP A C   1 
ATOM   1401  O O   . ASP A 1 176 ? -41.616 -32.221 37.303  1.00 43.47  ? 176 ASP A O   1 
ATOM   1402  C CB  . ASP A 1 176 ? -40.723 -35.218 38.253  1.00 38.35  ? 176 ASP A CB  1 
ATOM   1403  C CG  . ASP A 1 176 ? -40.878 -36.162 39.436  1.00 37.75  ? 176 ASP A CG  1 
ATOM   1404  O OD1 . ASP A 1 176 ? -41.675 -35.840 40.365  1.00 42.69  ? 176 ASP A OD1 1 
ATOM   1405  O OD2 . ASP A 1 176 ? -40.122 -37.182 39.468  1.00 38.17  ? 176 ASP A OD2 1 
ATOM   1406  N N   . LEU A 1 177 ? -41.132 -33.640 35.650  1.00 37.47  ? 177 LEU A N   1 
ATOM   1407  C CA  . LEU A 1 177 ? -40.636 -32.568 34.800  1.00 36.42  ? 177 LEU A CA  1 
ATOM   1408  C C   . LEU A 1 177 ? -41.809 -31.708 34.340  1.00 34.12  ? 177 LEU A C   1 
ATOM   1409  O O   . LEU A 1 177 ? -41.719 -30.491 34.348  1.00 39.14  ? 177 LEU A O   1 
ATOM   1410  C CB  . LEU A 1 177 ? -39.865 -33.182 33.630  1.00 40.39  ? 177 LEU A CB  1 
ATOM   1411  C CG  . LEU A 1 177 ? -39.251 -32.203 32.634  1.00 44.16  ? 177 LEU A CG  1 
ATOM   1412  C CD1 . LEU A 1 177 ? -38.496 -31.082 33.338  1.00 41.43  ? 177 LEU A CD1 1 
ATOM   1413  C CD2 . LEU A 1 177 ? -38.321 -32.942 31.681  1.00 43.35  ? 177 LEU A CD2 1 
ATOM   1414  N N   . MET A 1 178 ? -42.952 -32.323 34.023  1.00 33.29  ? 178 MET A N   1 
ATOM   1415  C CA  . MET A 1 178 ? -44.082 -31.550 33.538  1.00 34.50  ? 178 MET A CA  1 
ATOM   1416  C C   . MET A 1 178 ? -44.565 -30.604 34.638  1.00 36.86  ? 178 MET A C   1 
ATOM   1417  O O   . MET A 1 178 ? -44.940 -29.474 34.348  1.00 40.36  ? 178 MET A O   1 
ATOM   1418  C CB  . MET A 1 178 ? -45.240 -32.435 33.054  1.00 36.34  ? 178 MET A CB  1 
ATOM   1419  C CG  . MET A 1 178 ? -46.329 -31.635 32.270  1.00 38.84  ? 178 MET A CG  1 
ATOM   1420  S SD  . MET A 1 178 ? -45.706 -30.815 30.696  1.00 45.18  ? 178 MET A SD  1 
ATOM   1421  C CE  . MET A 1 178 ? -46.018 -29.087 31.057  1.00 44.25  ? 178 MET A CE  1 
ATOM   1422  N N   . ALA A 1 179 ? -44.530 -31.052 35.907  1.00 37.87  ? 179 ALA A N   1 
ATOM   1423  C CA  . ALA A 1 179 ? -45.050 -30.272 37.021  1.00 35.59  ? 179 ALA A CA  1 
ATOM   1424  C C   . ALA A 1 179 ? -44.183 -29.047 37.315  1.00 36.35  ? 179 ALA A C   1 
ATOM   1425  O O   . ALA A 1 179 ? -44.691 -28.061 37.854  1.00 39.86  ? 179 ALA A O   1 
ATOM   1426  C CB  . ALA A 1 179 ? -45.187 -31.146 38.241  1.00 35.36  ? 179 ALA A CB  1 
ATOM   1427  N N   . LYS A 1 180 ? -42.892 -29.098 36.940  1.00 37.24  ? 180 LYS A N   1 
ATOM   1428  C CA  . LYS A 1 180 ? -41.928 -28.046 37.257  1.00 36.53  ? 180 LYS A CA  1 
ATOM   1429  C C   . LYS A 1 180 ? -41.699 -27.057 36.121  1.00 31.80  ? 180 LYS A C   1 
ATOM   1430  O O   . LYS A 1 180 ? -41.272 -25.952 36.421  1.00 35.67  ? 180 LYS A O   1 
ATOM   1431  C CB  . LYS A 1 180 ? -40.547 -28.621 37.571  1.00 40.25  ? 180 LYS A CB  1 
ATOM   1432  C CG  . LYS A 1 180 ? -40.487 -29.491 38.813  1.00 42.86  ? 180 LYS A CG  1 
ATOM   1433  C CD  . LYS A 1 180 ? -39.132 -30.134 39.018  1.00 48.02  ? 180 LYS A CD  1 
ATOM   1434  C CE  . LYS A 1 180 ? -39.196 -31.442 39.777  1.00 54.29  ? 180 LYS A CE  1 
ATOM   1435  N NZ  . LYS A 1 180 ? -39.979 -31.299 41.026  1.00 57.59  ? 180 LYS A NZ  1 
ATOM   1436  N N   . LEU A 1 181 ? -41.931 -27.431 34.852  1.00 30.64  ? 181 LEU A N   1 
ATOM   1437  C CA  . LEU A 1 181 ? -41.585 -26.560 33.732  1.00 31.07  ? 181 LEU A CA  1 
ATOM   1438  C C   . LEU A 1 181 ? -42.228 -25.171 33.809  1.00 33.42  ? 181 LEU A C   1 
ATOM   1439  O O   . LEU A 1 181 ? -41.636 -24.183 33.355  1.00 34.83  ? 181 LEU A O   1 
ATOM   1440  C CB  . LEU A 1 181 ? -42.001 -27.216 32.420  1.00 30.91  ? 181 LEU A CB  1 
ATOM   1441  C CG  . LEU A 1 181 ? -41.106 -28.360 31.974  1.00 34.52  ? 181 LEU A CG  1 
ATOM   1442  C CD1 . LEU A 1 181 ? -41.600 -28.964 30.668  1.00 37.02  ? 181 LEU A CD1 1 
ATOM   1443  C CD2 . LEU A 1 181 ? -39.662 -27.895 31.846  1.00 38.10  ? 181 LEU A CD2 1 
ATOM   1444  N N   . PRO A 1 182 ? -43.492 -25.026 34.262  1.00 33.52  ? 182 PRO A N   1 
ATOM   1445  C CA  . PRO A 1 182 ? -44.079 -23.692 34.386  1.00 32.21  ? 182 PRO A CA  1 
ATOM   1446  C C   . PRO A 1 182 ? -43.392 -22.823 35.438  1.00 31.72  ? 182 PRO A C   1 
ATOM   1447  O O   . PRO A 1 182 ? -43.123 -21.648 35.181  1.00 29.86  ? 182 PRO A O   1 
ATOM   1448  C CB  . PRO A 1 182 ? -45.546 -23.982 34.723  1.00 35.53  ? 182 PRO A CB  1 
ATOM   1449  C CG  . PRO A 1 182 ? -45.768 -25.415 34.242  1.00 32.48  ? 182 PRO A CG  1 
ATOM   1450  C CD  . PRO A 1 182 ? -44.455 -26.104 34.535  1.00 30.71  ? 182 PRO A CD  1 
ATOM   1451  N N   . SER A 1 183 ? -43.078 -23.412 36.600  1.00 33.72  ? 183 SER A N   1 
ATOM   1452  C CA  . SER A 1 183 ? -42.237 -22.744 37.591  1.00 34.60  ? 183 SER A CA  1 
ATOM   1453  C C   . SER A 1 183 ? -40.901 -22.326 36.976  1.00 34.51  ? 183 SER A C   1 
ATOM   1454  O O   . SER A 1 183 ? -40.451 -21.205 37.209  1.00 39.96  ? 183 SER A O   1 
ATOM   1455  C CB  . SER A 1 183 ? -41.978 -23.571 38.820  1.00 34.95  ? 183 SER A CB  1 
ATOM   1456  O OG  . SER A 1 183 ? -43.174 -23.881 39.510  1.00 38.88  ? 183 SER A OG  1 
ATOM   1457  N N   . LEU A 1 184 ? -40.260 -23.218 36.215  1.00 32.61  ? 184 LEU A N   1 
ATOM   1458  C CA  . LEU A 1 184 ? -38.965 -22.900 35.622  1.00 31.11  ? 184 LEU A CA  1 
ATOM   1459  C C   . LEU A 1 184 ? -39.098 -21.705 34.690  1.00 28.47  ? 184 LEU A C   1 
ATOM   1460  O O   . LEU A 1 184 ? -38.353 -20.733 34.829  1.00 26.15  ? 184 LEU A O   1 
ATOM   1461  C CB  . LEU A 1 184 ? -38.406 -24.101 34.864  1.00 32.93  ? 184 LEU A CB  1 
ATOM   1462  C CG  . LEU A 1 184 ? -37.070 -23.838 34.173  1.00 35.87  ? 184 LEU A CG  1 
ATOM   1463  C CD1 . LEU A 1 184 ? -36.108 -23.142 35.122  1.00 36.91  ? 184 LEU A CD1 1 
ATOM   1464  C CD2 . LEU A 1 184 ? -36.446 -25.130 33.673  1.00 34.99  ? 184 LEU A CD2 1 
ATOM   1465  N N   . GLY A 1 185 ? -40.084 -21.767 33.784  1.00 27.85  ? 185 GLY A N   1 
ATOM   1466  C CA  . GLY A 1 185 ? -40.338 -20.669 32.863  1.00 25.35  ? 185 GLY A CA  1 
ATOM   1467  C C   . GLY A 1 185 ? -40.559 -19.336 33.585  1.00 27.17  ? 185 GLY A C   1 
ATOM   1468  O O   . GLY A 1 185 ? -39.976 -18.303 33.236  1.00 26.01  ? 185 GLY A O   1 
ATOM   1469  N N   . ALA A 1 186 ? -41.419 -19.367 34.609  1.00 28.50  ? 186 ALA A N   1 
ATOM   1470  C CA  . ALA A 1 186 ? -41.742 -18.172 35.369  1.00 26.47  ? 186 ALA A CA  1 
ATOM   1471  C C   . ALA A 1 186 ? -40.504 -17.633 36.078  1.00 29.21  ? 186 ALA A C   1 
ATOM   1472  O O   . ALA A 1 186 ? -40.311 -16.428 36.081  1.00 31.85  ? 186 ALA A O   1 
ATOM   1473  C CB  . ALA A 1 186 ? -42.846 -18.459 36.363  1.00 26.24  ? 186 ALA A CB  1 
ATOM   1474  N N   . TYR A 1 187 ? -39.672 -18.503 36.674  1.00 29.42  ? 187 TYR A N   1 
ATOM   1475  C CA  . TYR A 1 187 ? -38.464 -18.040 37.355  1.00 29.09  ? 187 TYR A CA  1 
ATOM   1476  C C   . TYR A 1 187 ? -37.589 -17.215 36.408  1.00 29.58  ? 187 TYR A C   1 
ATOM   1477  O O   . TYR A 1 187 ? -37.078 -16.160 36.779  1.00 29.17  ? 187 TYR A O   1 
ATOM   1478  C CB  . TYR A 1 187 ? -37.580 -19.198 37.836  1.00 32.81  ? 187 TYR A CB  1 
ATOM   1479  C CG  . TYR A 1 187 ? -36.552 -18.751 38.838  1.00 37.35  ? 187 TYR A CG  1 
ATOM   1480  C CD1 . TYR A 1 187 ? -36.884 -18.682 40.183  1.00 39.38  ? 187 TYR A CD1 1 
ATOM   1481  C CD2 . TYR A 1 187 ? -35.282 -18.318 38.455  1.00 39.49  ? 187 TYR A CD2 1 
ATOM   1482  C CE1 . TYR A 1 187 ? -35.978 -18.212 41.126  1.00 42.92  ? 187 TYR A CE1 1 
ATOM   1483  C CE2 . TYR A 1 187 ? -34.365 -17.848 39.393  1.00 41.84  ? 187 TYR A CE2 1 
ATOM   1484  C CZ  . TYR A 1 187 ? -34.719 -17.784 40.737  1.00 42.53  ? 187 TYR A CZ  1 
ATOM   1485  O OH  . TYR A 1 187 ? -33.884 -17.305 41.737  1.00 50.89  ? 187 TYR A OH  1 
ATOM   1486  N N   . ILE A 1 188 ? -37.402 -17.730 35.186  1.00 29.02  ? 188 ILE A N   1 
ATOM   1487  C CA  . ILE A 1 188 ? -36.597 -17.081 34.161  1.00 27.94  ? 188 ILE A CA  1 
ATOM   1488  C C   . ILE A 1 188 ? -37.232 -15.740 33.778  1.00 32.63  ? 188 ILE A C   1 
ATOM   1489  O O   . ILE A 1 188 ? -36.524 -14.721 33.713  1.00 34.91  ? 188 ILE A O   1 
ATOM   1490  C CB  . ILE A 1 188 ? -36.408 -18.034 32.973  1.00 26.90  ? 188 ILE A CB  1 
ATOM   1491  C CG1 . ILE A 1 188 ? -35.527 -19.209 33.394  1.00 27.33  ? 188 ILE A CG1 1 
ATOM   1492  C CG2 . ILE A 1 188 ? -35.866 -17.338 31.736  1.00 27.51  ? 188 ILE A CG2 1 
ATOM   1493  C CD1 . ILE A 1 188 ? -35.576 -20.359 32.381  1.00 27.76  ? 188 ILE A CD1 1 
ATOM   1494  N N   . TYR A 1 189 ? -38.561 -15.716 33.569  1.00 29.97  ? 189 TYR A N   1 
ATOM   1495  C CA  . TYR A 1 189 ? -39.231 -14.456 33.264  1.00 26.62  ? 189 TYR A CA  1 
ATOM   1496  C C   . TYR A 1 189 ? -38.918 -13.402 34.310  1.00 25.25  ? 189 TYR A C   1 
ATOM   1497  O O   . TYR A 1 189 ? -38.608 -12.286 33.966  1.00 29.71  ? 189 TYR A O   1 
ATOM   1498  C CB  . TYR A 1 189 ? -40.749 -14.562 33.305  1.00 26.67  ? 189 TYR A CB  1 
ATOM   1499  C CG  . TYR A 1 189 ? -41.465 -13.359 32.748  1.00 26.29  ? 189 TYR A CG  1 
ATOM   1500  C CD1 . TYR A 1 189 ? -41.245 -12.955 31.451  1.00 28.72  ? 189 TYR A CD1 1 
ATOM   1501  C CD2 . TYR A 1 189 ? -42.425 -12.675 33.486  1.00 27.00  ? 189 TYR A CD2 1 
ATOM   1502  C CE1 . TYR A 1 189 ? -41.924 -11.867 30.923  1.00 33.67  ? 189 TYR A CE1 1 
ATOM   1503  C CE2 . TYR A 1 189 ? -43.120 -11.592 32.973  1.00 24.68  ? 189 TYR A CE2 1 
ATOM   1504  C CZ  . TYR A 1 189 ? -42.876 -11.193 31.675  1.00 29.58  ? 189 TYR A CZ  1 
ATOM   1505  O OH  . TYR A 1 189 ? -43.529 -10.138 31.073  1.00 36.82  ? 189 TYR A OH  1 
ATOM   1506  N N   . ARG A 1 190 ? -39.053 -13.761 35.580  1.00 25.39  ? 190 ARG A N   1 
ATOM   1507  C CA  . ARG A 1 190 ? -38.965 -12.811 36.663  1.00 27.22  ? 190 ARG A CA  1 
ATOM   1508  C C   . ARG A 1 190 ? -37.517 -12.380 36.845  1.00 28.59  ? 190 ARG A C   1 
ATOM   1509  O O   . ARG A 1 190 ? -37.241 -11.214 37.070  1.00 30.35  ? 190 ARG A O   1 
ATOM   1510  C CB  . ARG A 1 190 ? -39.439 -13.437 37.976  1.00 26.55  ? 190 ARG A CB  1 
ATOM   1511  C CG  . ARG A 1 190 ? -40.873 -13.912 37.957  1.00 27.88  ? 190 ARG A CG  1 
ATOM   1512  C CD  . ARG A 1 190 ? -41.849 -12.804 37.652  1.00 27.33  ? 190 ARG A CD  1 
ATOM   1513  N NE  . ARG A 1 190 ? -41.977 -11.935 38.810  1.00 28.67  ? 190 ARG A NE  1 
ATOM   1514  C CZ  . ARG A 1 190 ? -42.741 -10.833 38.822  1.00 29.82  ? 190 ARG A CZ  1 
ATOM   1515  N NH1 . ARG A 1 190 ? -43.658 -10.627 37.870  1.00 21.86  ? 190 ARG A NH1 1 
ATOM   1516  N NH2 . ARG A 1 190 ? -42.547 -9.941  39.780  1.00 23.67  ? 190 ARG A NH2 1 
ATOM   1517  N N   . MET A 1 191 ? -36.603 -13.348 36.814  1.00 33.08  ? 191 MET A N   1 
ATOM   1518  C CA  . MET A 1 191 ? -35.203 -13.082 37.087  1.00 31.39  ? 191 MET A CA  1 
ATOM   1519  C C   . MET A 1 191 ? -34.607 -12.176 36.005  1.00 29.55  ? 191 MET A C   1 
ATOM   1520  O O   . MET A 1 191 ? -33.730 -11.347 36.286  1.00 24.40  ? 191 MET A O   1 
ATOM   1521  C CB  . MET A 1 191 ? -34.442 -14.410 37.219  1.00 33.38  ? 191 MET A CB  1 
ATOM   1522  C CG  . MET A 1 191 ? -33.670 -14.816 35.972  1.00 37.64  ? 191 MET A CG  1 
ATOM   1523  S SD  . MET A 1 191 ? -32.719 -16.367 36.137  1.00 39.07  ? 191 MET A SD  1 
ATOM   1524  C CE  . MET A 1 191 ? -31.681 -15.892 37.530  1.00 36.78  ? 191 MET A CE  1 
ATOM   1525  N N   . LYS A 1 192 ? -35.102 -12.325 34.770  1.00 27.55  ? 192 LYS A N   1 
ATOM   1526  C CA  . LYS A 1 192 ? -34.557 -11.590 33.642  1.00 31.16  ? 192 LYS A CA  1 
ATOM   1527  C C   . LYS A 1 192 ? -35.299 -10.268 33.463  1.00 31.24  ? 192 LYS A C   1 
ATOM   1528  O O   . LYS A 1 192 ? -34.661 -9.253  33.210  1.00 33.08  ? 192 LYS A O   1 
ATOM   1529  C CB  . LYS A 1 192 ? -34.613 -12.397 32.338  1.00 31.74  ? 192 LYS A CB  1 
ATOM   1530  C CG  . LYS A 1 192 ? -33.422 -13.307 32.077  1.00 34.03  ? 192 LYS A CG  1 
ATOM   1531  C CD  . LYS A 1 192 ? -33.323 -13.833 30.647  1.00 39.31  ? 192 LYS A CD  1 
ATOM   1532  C CE  . LYS A 1 192 ? -32.876 -12.809 29.616  1.00 41.50  ? 192 LYS A CE  1 
ATOM   1533  N NZ  . LYS A 1 192 ? -31.403 -12.707 29.526  1.00 41.42  ? 192 LYS A NZ  1 
ATOM   1534  N N   . TYR A 1 193 ? -36.625 -10.271 33.627  1.00 27.46  ? 193 TYR A N   1 
ATOM   1535  C CA  . TYR A 1 193 ? -37.465 -9.238  33.047  1.00 26.35  ? 193 TYR A CA  1 
ATOM   1536  C C   . TYR A 1 193 ? -38.224 -8.449  34.095  1.00 25.65  ? 193 TYR A C   1 
ATOM   1537  O O   . TYR A 1 193 ? -38.767 -7.406  33.751  1.00 34.39  ? 193 TYR A O   1 
ATOM   1538  C CB  . TYR A 1 193 ? -38.434 -9.867  32.026  1.00 27.88  ? 193 TYR A CB  1 
ATOM   1539  C CG  . TYR A 1 193 ? -37.729 -10.494 30.846  1.00 28.03  ? 193 TYR A CG  1 
ATOM   1540  C CD1 . TYR A 1 193 ? -36.838 -9.729  30.076  1.00 26.44  ? 193 TYR A CD1 1 
ATOM   1541  C CD2 . TYR A 1 193 ? -37.923 -11.819 30.481  1.00 24.63  ? 193 TYR A CD2 1 
ATOM   1542  C CE1 . TYR A 1 193 ? -36.152 -10.258 28.991  1.00 22.97  ? 193 TYR A CE1 1 
ATOM   1543  C CE2 . TYR A 1 193 ? -37.235 -12.361 29.400  1.00 25.49  ? 193 TYR A CE2 1 
ATOM   1544  C CZ  . TYR A 1 193 ? -36.342 -11.585 28.657  1.00 26.55  ? 193 TYR A CZ  1 
ATOM   1545  O OH  . TYR A 1 193 ? -35.609 -12.074 27.562  1.00 32.41  ? 193 TYR A OH  1 
ATOM   1546  N N   . LYS A 1 194 ? -38.329 -8.942  35.331  1.00 30.95  ? 194 LYS A N   1 
ATOM   1547  C CA  . LYS A 1 194 ? -39.232 -8.366  36.331  1.00 31.44  ? 194 LYS A CA  1 
ATOM   1548  C C   . LYS A 1 194 ? -38.512 -8.096  37.639  1.00 33.29  ? 194 LYS A C   1 
ATOM   1549  O O   . LYS A 1 194 ? -39.070 -8.332  38.718  1.00 30.90  ? 194 LYS A O   1 
ATOM   1550  C CB  . LYS A 1 194 ? -40.402 -9.293  36.654  1.00 35.80  ? 194 LYS A CB  1 
ATOM   1551  C CG  . LYS A 1 194 ? -41.335 -9.511  35.477  1.00 41.56  ? 194 LYS A CG  1 
ATOM   1552  C CD  . LYS A 1 194 ? -42.241 -8.315  35.278  1.00 43.15  ? 194 LYS A CD  1 
ATOM   1553  C CE  . LYS A 1 194 ? -42.446 -7.980  33.826  1.00 45.37  ? 194 LYS A CE  1 
ATOM   1554  N NZ  . LYS A 1 194 ? -43.207 -6.724  33.724  1.00 49.54  ? 194 LYS A NZ  1 
ATOM   1555  N N   . SER A 1 195 ? -37.271 -7.599  37.526  1.00 40.33  ? 195 SER A N   1 
ATOM   1556  C CA  . SER A 1 195 ? -36.513 -7.152  38.687  1.00 45.23  ? 195 SER A CA  1 
ATOM   1557  C C   . SER A 1 195 ? -36.129 -8.290  39.643  1.00 38.56  ? 195 SER A C   1 
ATOM   1558  O O   . SER A 1 195 ? -35.797 -8.017  40.794  1.00 41.68  ? 195 SER A O   1 
ATOM   1559  C CB  . SER A 1 195 ? -37.265 -6.044  39.423  1.00 45.16  ? 195 SER A CB  1 
ATOM   1560  O OG  . SER A 1 195 ? -37.264 -4.862  38.642  1.00 43.95  ? 195 SER A OG  1 
ATOM   1561  N N   . ASP A 1 196 ? -36.141 -9.543  39.167  1.00 37.16  ? 196 ASP A N   1 
ATOM   1562  C CA  . ASP A 1 196 ? -35.720 -10.682 39.968  1.00 34.63  ? 196 ASP A CA  1 
ATOM   1563  C C   . ASP A 1 196 ? -36.457 -10.657 41.312  1.00 35.55  ? 196 ASP A C   1 
ATOM   1564  O O   . ASP A 1 196 ? -35.893 -11.022 42.352  1.00 37.39  ? 196 ASP A O   1 
ATOM   1565  C CB  . ASP A 1 196 ? -34.192 -10.699 40.134  1.00 32.86  ? 196 ASP A CB  1 
ATOM   1566  C CG  . ASP A 1 196 ? -33.529 -12.052 40.421  1.00 35.01  ? 196 ASP A CG  1 
ATOM   1567  O OD1 . ASP A 1 196 ? -34.210 -13.127 40.264  1.00 35.06  ? 196 ASP A OD1 1 
ATOM   1568  O OD2 . ASP A 1 196 ? -32.317 -12.032 40.802  1.00 32.11  ? 196 ASP A OD2 1 
ATOM   1569  N N   . THR A 1 197 ? -37.736 -10.259 41.300  1.00 32.88  ? 197 THR A N   1 
ATOM   1570  C CA  . THR A 1 197 ? -38.576 -10.566 42.453  1.00 33.05  ? 197 THR A CA  1 
ATOM   1571  C C   . THR A 1 197 ? -39.560 -11.657 42.046  1.00 35.01  ? 197 THR A C   1 
ATOM   1572  O O   . THR A 1 197 ? -40.150 -11.623 40.958  1.00 36.35  ? 197 THR A O   1 
ATOM   1573  C CB  . THR A 1 197 ? -39.306 -9.340  43.009  1.00 32.71  ? 197 THR A CB  1 
ATOM   1574  O OG1 . THR A 1 197 ? -40.197 -8.938  41.966  1.00 33.43  ? 197 THR A OG1 1 
ATOM   1575  C CG2 . THR A 1 197 ? -38.382 -8.196  43.383  1.00 32.41  ? 197 THR A CG2 1 
ATOM   1576  N N   . HIS A 1 198 ? -39.760 -12.587 42.991  1.00 35.75  ? 198 HIS A N   1 
ATOM   1577  C CA  . HIS A 1 198 ? -40.425 -13.846 42.714  1.00 37.21  ? 198 HIS A CA  1 
ATOM   1578  C C   . HIS A 1 198 ? -41.732 -13.928 43.494  1.00 41.94  ? 198 HIS A C   1 
ATOM   1579  O O   . HIS A 1 198 ? -41.762 -13.699 44.705  1.00 38.40  ? 198 HIS A O   1 
ATOM   1580  C CB  . HIS A 1 198 ? -39.451 -15.003 43.003  1.00 31.86  ? 198 HIS A CB  1 
ATOM   1581  C CG  . HIS A 1 198 ? -38.269 -14.950 42.084  1.00 30.92  ? 198 HIS A CG  1 
ATOM   1582  N ND1 . HIS A 1 198 ? -38.199 -15.594 40.859  1.00 31.31  ? 198 HIS A ND1 1 
ATOM   1583  C CD2 . HIS A 1 198 ? -37.183 -14.116 42.152  1.00 29.29  ? 198 HIS A CD2 1 
ATOM   1584  C CE1 . HIS A 1 198 ? -37.062 -15.216 40.241  1.00 31.42  ? 198 HIS A CE1 1 
ATOM   1585  N NE2 . HIS A 1 198 ? -36.431 -14.282 41.015  1.00 26.99  ? 198 HIS A NE2 1 
ATOM   1586  N N   . ILE A 1 199 ? -42.808 -14.249 42.765  1.00 43.62  ? 199 ILE A N   1 
ATOM   1587  C CA  . ILE A 1 199 ? -44.080 -14.549 43.399  1.00 45.53  ? 199 ILE A CA  1 
ATOM   1588  C C   . ILE A 1 199 ? -44.117 -16.046 43.670  1.00 41.95  ? 199 ILE A C   1 
ATOM   1589  O O   . ILE A 1 199 ? -43.871 -16.835 42.752  1.00 44.01  ? 199 ILE A O   1 
ATOM   1590  C CB  . ILE A 1 199 ? -45.226 -14.069 42.486  1.00 49.32  ? 199 ILE A CB  1 
ATOM   1591  C CG1 . ILE A 1 199 ? -45.070 -12.568 42.212  1.00 44.35  ? 199 ILE A CG1 1 
ATOM   1592  C CG2 . ILE A 1 199 ? -46.605 -14.466 43.035  1.00 47.29  ? 199 ILE A CG2 1 
ATOM   1593  C CD1 . ILE A 1 199 ? -45.796 -12.114 40.979  1.00 47.04  ? 199 ILE A CD1 1 
ATOM   1594  N N   . PRO A 1 200 ? -44.388 -16.485 44.921  1.00 43.15  ? 200 PRO A N   1 
ATOM   1595  C CA  . PRO A 1 200 ? -44.442 -17.917 45.226  1.00 51.30  ? 200 PRO A CA  1 
ATOM   1596  C C   . PRO A 1 200 ? -45.621 -18.602 44.524  1.00 57.33  ? 200 PRO A C   1 
ATOM   1597  O O   . PRO A 1 200 ? -46.669 -17.990 44.232  1.00 58.52  ? 200 PRO A O   1 
ATOM   1598  C CB  . PRO A 1 200 ? -44.592 -18.001 46.760  1.00 46.28  ? 200 PRO A CB  1 
ATOM   1599  C CG  . PRO A 1 200 ? -45.155 -16.639 47.167  1.00 44.50  ? 200 PRO A CG  1 
ATOM   1600  C CD  . PRO A 1 200 ? -44.695 -15.657 46.097  1.00 45.04  ? 200 PRO A CD  1 
ATOM   1601  N N   . SER A 1 201 ? -45.423 -19.889 44.239  1.00 50.03  ? 201 SER A N   1 
ATOM   1602  C CA  . SER A 1 201 ? -46.498 -20.708 43.707  1.00 50.03  ? 201 SER A CA  1 
ATOM   1603  C C   . SER A 1 201 ? -47.621 -20.822 44.749  1.00 50.72  ? 201 SER A C   1 
ATOM   1604  O O   . SER A 1 201 ? -47.371 -20.920 45.958  1.00 46.97  ? 201 SER A O   1 
ATOM   1605  C CB  . SER A 1 201 ? -45.976 -22.049 43.258  1.00 47.54  ? 201 SER A CB  1 
ATOM   1606  O OG  . SER A 1 201 ? -46.960 -23.037 43.420  1.00 46.23  ? 201 SER A OG  1 
ATOM   1607  N N   . ASN A 1 202 ? -48.869 -20.766 44.242  1.00 48.46  ? 202 ASN A N   1 
ATOM   1608  C CA  . ASN A 1 202 ? -50.073 -20.903 45.039  1.00 47.02  ? 202 ASN A CA  1 
ATOM   1609  C C   . ASN A 1 202 ? -50.610 -22.327 44.916  1.00 54.63  ? 202 ASN A C   1 
ATOM   1610  O O   . ASN A 1 202 ? -51.090 -22.721 43.843  1.00 47.43  ? 202 ASN A O   1 
ATOM   1611  C CB  . ASN A 1 202 ? -51.146 -19.915 44.584  1.00 49.83  ? 202 ASN A CB  1 
ATOM   1612  C CG  . ASN A 1 202 ? -52.327 -19.827 45.530  1.00 47.40  ? 202 ASN A CG  1 
ATOM   1613  O OD1 . ASN A 1 202 ? -52.535 -20.665 46.406  1.00 48.73  ? 202 ASN A OD1 1 
ATOM   1614  N ND2 . ASN A 1 202 ? -53.103 -18.776 45.365  1.00 46.66  ? 202 ASN A ND2 1 
ATOM   1615  N N   . PRO A 1 203 ? -50.573 -23.133 46.008  1.00 59.97  ? 203 PRO A N   1 
ATOM   1616  C CA  . PRO A 1 203 ? -51.074 -24.513 45.967  1.00 60.96  ? 203 PRO A CA  1 
ATOM   1617  C C   . PRO A 1 203 ? -52.557 -24.685 45.634  1.00 58.64  ? 203 PRO A C   1 
ATOM   1618  O O   . PRO A 1 203 ? -52.998 -25.799 45.377  1.00 67.27  ? 203 PRO A O   1 
ATOM   1619  C CB  . PRO A 1 203 ? -50.827 -25.026 47.393  1.00 60.84  ? 203 PRO A CB  1 
ATOM   1620  C CG  . PRO A 1 203 ? -50.767 -23.765 48.225  1.00 63.76  ? 203 PRO A CG  1 
ATOM   1621  C CD  . PRO A 1 203 ? -50.058 -22.763 47.335  1.00 59.57  ? 203 PRO A CD  1 
ATOM   1622  N N   . ASP A 1 204 ? -53.327 -23.589 45.612  1.00 57.62  ? 204 ASP A N   1 
ATOM   1623  C CA  . ASP A 1 204 ? -54.761 -23.666 45.363  1.00 61.65  ? 204 ASP A CA  1 
ATOM   1624  C C   . ASP A 1 204 ? -55.069 -23.465 43.874  1.00 56.83  ? 204 ASP A C   1 
ATOM   1625  O O   . ASP A 1 204 ? -56.241 -23.371 43.507  1.00 52.64  ? 204 ASP A O   1 
ATOM   1626  C CB  . ASP A 1 204 ? -55.533 -22.659 46.238  1.00 64.54  ? 204 ASP A CB  1 
ATOM   1627  C CG  . ASP A 1 204 ? -55.376 -22.856 47.755  1.00 71.97  ? 204 ASP A CG  1 
ATOM   1628  O OD1 . ASP A 1 204 ? -55.559 -24.003 48.233  1.00 64.42  ? 204 ASP A OD1 1 
ATOM   1629  O OD2 . ASP A 1 204 ? -55.069 -21.864 48.479  1.00 76.10  ? 204 ASP A OD2 1 
ATOM   1630  N N   . LEU A 1 205 ? -54.038 -23.372 43.019  1.00 51.90  ? 205 LEU A N   1 
ATOM   1631  C CA  . LEU A 1 205 ? -54.234 -22.964 41.631  1.00 50.17  ? 205 LEU A CA  1 
ATOM   1632  C C   . LEU A 1 205 ? -53.868 -24.103 40.679  1.00 45.24  ? 205 LEU A C   1 
ATOM   1633  O O   . LEU A 1 205 ? -52.974 -24.899 40.947  1.00 45.56  ? 205 LEU A O   1 
ATOM   1634  C CB  . LEU A 1 205 ? -53.392 -21.717 41.321  1.00 49.92  ? 205 LEU A CB  1 
ATOM   1635  C CG  . LEU A 1 205 ? -53.957 -20.359 41.751  1.00 50.82  ? 205 LEU A CG  1 
ATOM   1636  C CD1 . LEU A 1 205 ? -53.029 -19.249 41.296  1.00 54.22  ? 205 LEU A CD1 1 
ATOM   1637  C CD2 . LEU A 1 205 ? -55.346 -20.110 41.184  1.00 44.51  ? 205 LEU A CD2 1 
ATOM   1638  N N   . ASP A 1 206 ? -54.567 -24.161 39.543  1.00 41.22  ? 206 ASP A N   1 
ATOM   1639  C CA  . ASP A 1 206 ? -54.211 -25.101 38.509  1.00 46.02  ? 206 ASP A CA  1 
ATOM   1640  C C   . ASP A 1 206 ? -52.916 -24.619 37.841  1.00 47.94  ? 206 ASP A C   1 
ATOM   1641  O O   . ASP A 1 206 ? -52.451 -23.512 38.081  1.00 47.17  ? 206 ASP A O   1 
ATOM   1642  C CB  . ASP A 1 206 ? -55.358 -25.268 37.505  1.00 55.26  ? 206 ASP A CB  1 
ATOM   1643  C CG  . ASP A 1 206 ? -55.439 -24.167 36.449  1.00 54.76  ? 206 ASP A CG  1 
ATOM   1644  O OD1 . ASP A 1 206 ? -55.978 -23.096 36.801  1.00 45.03  ? 206 ASP A OD1 1 
ATOM   1645  O OD2 . ASP A 1 206 ? -54.953 -24.404 35.264  1.00 55.02  ? 206 ASP A OD2 1 
ATOM   1646  N N   . LEU A 1 207 ? -52.364 -25.457 36.958  1.00 44.76  ? 207 LEU A N   1 
ATOM   1647  C CA  . LEU A 1 207 ? -51.100 -25.204 36.290  1.00 44.35  ? 207 LEU A CA  1 
ATOM   1648  C C   . LEU A 1 207 ? -51.119 -23.858 35.563  1.00 42.98  ? 207 LEU A C   1 
ATOM   1649  O O   . LEU A 1 207 ? -50.257 -23.014 35.803  1.00 46.21  ? 207 LEU A O   1 
ATOM   1650  C CB  . LEU A 1 207 ? -50.847 -26.391 35.361  1.00 41.40  ? 207 LEU A CB  1 
ATOM   1651  C CG  . LEU A 1 207 ? -49.516 -26.374 34.630  1.00 46.65  ? 207 LEU A CG  1 
ATOM   1652  C CD1 . LEU A 1 207 ? -49.119 -27.793 34.233  1.00 45.65  ? 207 LEU A CD1 1 
ATOM   1653  C CD2 . LEU A 1 207 ? -49.565 -25.439 33.411  1.00 49.07  ? 207 LEU A CD2 1 
ATOM   1654  N N   . GLY A 1 208 ? -52.128 -23.642 34.716  1.00 45.39  ? 208 GLY A N   1 
ATOM   1655  C CA  . GLY A 1 208 ? -52.291 -22.391 33.988  1.00 45.69  ? 208 GLY A CA  1 
ATOM   1656  C C   . GLY A 1 208 ? -52.495 -21.179 34.905  1.00 47.50  ? 208 GLY A C   1 
ATOM   1657  O O   . GLY A 1 208 ? -51.900 -20.116 34.707  1.00 46.31  ? 208 GLY A O   1 
ATOM   1658  N N   . GLY A 1 209 ? -53.360 -21.334 35.907  1.00 45.88  ? 209 GLY A N   1 
ATOM   1659  C CA  . GLY A 1 209 ? -53.598 -20.267 36.864  1.00 40.41  ? 209 GLY A CA  1 
ATOM   1660  C C   . GLY A 1 209 ? -52.336 -19.960 37.662  1.00 38.63  ? 209 GLY A C   1 
ATOM   1661  O O   . GLY A 1 209 ? -52.003 -18.805 37.886  1.00 35.57  ? 209 GLY A O   1 
ATOM   1662  N N   . ASP A 1 210 ? -51.598 -21.008 38.038  1.00 35.78  ? 210 ASP A N   1 
ATOM   1663  C CA  . ASP A 1 210 ? -50.423 -20.823 38.858  1.00 40.37  ? 210 ASP A CA  1 
ATOM   1664  C C   . ASP A 1 210 ? -49.294 -20.160 38.053  1.00 41.01  ? 210 ASP A C   1 
ATOM   1665  O O   . ASP A 1 210 ? -48.485 -19.406 38.607  1.00 37.18  ? 210 ASP A O   1 
ATOM   1666  C CB  . ASP A 1 210 ? -49.982 -22.135 39.503  1.00 42.03  ? 210 ASP A CB  1 
ATOM   1667  C CG  . ASP A 1 210 ? -48.904 -21.865 40.539  1.00 45.37  ? 210 ASP A CG  1 
ATOM   1668  O OD1 . ASP A 1 210 ? -48.989 -20.790 41.223  1.00 48.14  ? 210 ASP A OD1 1 
ATOM   1669  O OD2 . ASP A 1 210 ? -47.973 -22.687 40.628  1.00 57.30  ? 210 ASP A OD2 1 
ATOM   1670  N N   . PHE A 1 211 ? -49.234 -20.448 36.750  1.00 33.88  ? 211 PHE A N   1 
ATOM   1671  C CA  . PHE A 1 211 ? -48.220 -19.860 35.901  1.00 32.89  ? 211 PHE A CA  1 
ATOM   1672  C C   . PHE A 1 211 ? -48.445 -18.344 35.805  1.00 37.31  ? 211 PHE A C   1 
ATOM   1673  O O   . PHE A 1 211 ? -47.524 -17.560 36.068  1.00 34.40  ? 211 PHE A O   1 
ATOM   1674  C CB  . PHE A 1 211 ? -48.252 -20.561 34.548  1.00 36.57  ? 211 PHE A CB  1 
ATOM   1675  C CG  . PHE A 1 211 ? -47.276 -19.996 33.557  1.00 36.79  ? 211 PHE A CG  1 
ATOM   1676  C CD1 . PHE A 1 211 ? -45.918 -20.264 33.688  1.00 39.68  ? 211 PHE A CD1 1 
ATOM   1677  C CD2 . PHE A 1 211 ? -47.711 -19.170 32.536  1.00 32.85  ? 211 PHE A CD2 1 
ATOM   1678  C CE1 . PHE A 1 211 ? -45.016 -19.721 32.791  1.00 39.46  ? 211 PHE A CE1 1 
ATOM   1679  C CE2 . PHE A 1 211 ? -46.804 -18.627 31.640  1.00 35.15  ? 211 PHE A CE2 1 
ATOM   1680  C CZ  . PHE A 1 211 ? -45.467 -18.900 31.772  1.00 39.77  ? 211 PHE A CZ  1 
ATOM   1681  N N   . ALA A 1 212 ? -49.682 -17.930 35.475  1.00 33.40  ? 212 ALA A N   1 
ATOM   1682  C CA  . ALA A 1 212 ? -50.051 -16.514 35.416  1.00 34.93  ? 212 ALA A CA  1 
ATOM   1683  C C   . ALA A 1 212 ? -49.713 -15.789 36.718  1.00 34.54  ? 212 ALA A C   1 
ATOM   1684  O O   . ALA A 1 212 ? -49.273 -14.641 36.709  1.00 38.64  ? 212 ALA A O   1 
ATOM   1685  C CB  . ALA A 1 212 ? -51.538 -16.371 35.135  1.00 34.34  ? 212 ALA A CB  1 
ATOM   1686  N N   . ASN A 1 213 ? -49.978 -16.477 37.831  1.00 34.49  ? 213 ASN A N   1 
ATOM   1687  C CA  . ASN A 1 213 ? -49.675 -16.020 39.174  1.00 39.81  ? 213 ASN A CA  1 
ATOM   1688  C C   . ASN A 1 213 ? -48.174 -15.726 39.293  1.00 43.24  ? 213 ASN A C   1 
ATOM   1689  O O   . ASN A 1 213 ? -47.766 -14.604 39.592  1.00 50.32  ? 213 ASN A O   1 
ATOM   1690  C CB  . ASN A 1 213 ? -50.165 -17.060 40.188  1.00 41.55  ? 213 ASN A CB  1 
ATOM   1691  C CG  . ASN A 1 213 ? -49.680 -16.815 41.605  1.00 46.22  ? 213 ASN A CG  1 
ATOM   1692  O OD1 . ASN A 1 213 ? -50.116 -15.856 42.242  1.00 40.15  ? 213 ASN A OD1 1 
ATOM   1693  N ND2 . ASN A 1 213 ? -48.822 -17.702 42.114  1.00 43.82  ? 213 ASN A ND2 1 
ATOM   1694  N N   . MET A 1 214 ? -47.350 -16.739 39.033  1.00 41.38  ? 214 MET A N   1 
ATOM   1695  C CA  . MET A 1 214 ? -45.912 -16.615 39.199  1.00 45.64  ? 214 MET A CA  1 
ATOM   1696  C C   . MET A 1 214 ? -45.326 -15.639 38.181  1.00 46.20  ? 214 MET A C   1 
ATOM   1697  O O   . MET A 1 214 ? -44.260 -15.064 38.420  1.00 44.47  ? 214 MET A O   1 
ATOM   1698  C CB  . MET A 1 214 ? -45.246 -17.973 39.007  1.00 44.23  ? 214 MET A CB  1 
ATOM   1699  C CG  . MET A 1 214 ? -45.715 -18.973 40.029  1.00 48.10  ? 214 MET A CG  1 
ATOM   1700  S SD  . MET A 1 214 ? -44.954 -20.575 39.820  1.00 44.32  ? 214 MET A SD  1 
ATOM   1701  C CE  . MET A 1 214 ? -43.705 -20.391 41.101  1.00 56.77  ? 214 MET A CE  1 
ATOM   1702  N N   . MET A 1 215 ? -46.006 -15.479 37.038  1.00 39.09  ? 215 MET A N   1 
ATOM   1703  C CA  . MET A 1 215 ? -45.560 -14.519 36.041  1.00 36.64  ? 215 MET A CA  1 
ATOM   1704  C C   . MET A 1 215 ? -45.860 -13.101 36.505  1.00 30.48  ? 215 MET A C   1 
ATOM   1705  O O   . MET A 1 215 ? -45.208 -12.155 36.092  1.00 29.94  ? 215 MET A O   1 
ATOM   1706  C CB  . MET A 1 215 ? -46.261 -14.781 34.710  1.00 36.26  ? 215 MET A CB  1 
ATOM   1707  C CG  . MET A 1 215 ? -45.726 -16.042 34.043  1.00 38.22  ? 215 MET A CG  1 
ATOM   1708  S SD  . MET A 1 215 ? -44.169 -15.786 33.141  1.00 36.43  ? 215 MET A SD  1 
ATOM   1709  C CE  . MET A 1 215 ? -44.727 -14.681 31.845  1.00 35.53  ? 215 MET A CE  1 
ATOM   1710  N N   . GLY A 1 216 ? -46.886 -12.977 37.349  1.00 34.36  ? 216 GLY A N   1 
ATOM   1711  C CA  . GLY A 1 216 ? -47.347 -11.705 37.885  1.00 33.36  ? 216 GLY A CA  1 
ATOM   1712  C C   . GLY A 1 216 ? -48.384 -11.029 36.986  1.00 38.93  ? 216 GLY A C   1 
ATOM   1713  O O   . GLY A 1 216 ? -48.451 -9.804  36.968  1.00 54.89  ? 216 GLY A O   1 
ATOM   1714  N N   . ILE A 1 217 ? -49.202 -11.804 36.247  1.00 38.57  ? 217 ILE A N   1 
ATOM   1715  C CA  . ILE A 1 217 ? -50.117 -11.235 35.266  1.00 38.78  ? 217 ILE A CA  1 
ATOM   1716  C C   . ILE A 1 217 ? -51.551 -11.614 35.646  1.00 46.12  ? 217 ILE A C   1 
ATOM   1717  O O   . ILE A 1 217 ? -51.815 -12.762 35.992  1.00 45.69  ? 217 ILE A O   1 
ATOM   1718  C CB  . ILE A 1 217 ? -49.707 -11.675 33.846  1.00 39.82  ? 217 ILE A CB  1 
ATOM   1719  C CG1 . ILE A 1 217 ? -48.223 -11.378 33.575  1.00 40.22  ? 217 ILE A CG1 1 
ATOM   1720  C CG2 . ILE A 1 217 ? -50.597 -11.046 32.769  1.00 36.59  ? 217 ILE A CG2 1 
ATOM   1721  C CD1 . ILE A 1 217 ? -47.714 -11.835 32.217  1.00 38.07  ? 217 ILE A CD1 1 
ATOM   1722  N N   . ASP A 1 218 ? -52.471 -10.636 35.604  1.00 52.94  ? 218 ASP A N   1 
ATOM   1723  C CA  . ASP A 1 218 ? -53.832 -10.817 36.098  1.00 57.84  ? 218 ASP A CA  1 
ATOM   1724  C C   . ASP A 1 218 ? -54.693 -11.521 35.048  1.00 58.67  ? 218 ASP A C   1 
ATOM   1725  O O   . ASP A 1 218 ? -54.309 -11.558 33.873  1.00 60.19  ? 218 ASP A O   1 
ATOM   1726  C CB  . ASP A 1 218 ? -54.549 -9.500  36.405  1.00 68.51  ? 218 ASP A CB  1 
ATOM   1727  C CG  . ASP A 1 218 ? -53.927 -8.598  37.453  1.00 77.57  ? 218 ASP A CG  1 
ATOM   1728  O OD1 . ASP A 1 218 ? -53.680 -9.085  38.582  1.00 83.66  ? 218 ASP A OD1 1 
ATOM   1729  O OD2 . ASP A 1 218 ? -53.745 -7.398  37.135  1.00 79.01  ? 218 ASP A OD2 1 
ATOM   1730  N N   . LYS A 1 219 ? -55.865 -12.032 35.496  1.00 61.23  ? 219 LYS A N   1 
ATOM   1731  C CA  . LYS A 1 219 ? -56.895 -12.585 34.619  1.00 65.13  ? 219 LYS A CA  1 
ATOM   1732  C C   . LYS A 1 219 ? -57.196 -11.577 33.510  1.00 58.31  ? 219 LYS A C   1 
ATOM   1733  O O   . LYS A 1 219 ? -57.261 -10.379 33.768  1.00 48.36  ? 219 LYS A O   1 
ATOM   1734  C CB  . LYS A 1 219 ? -58.244 -12.842 35.308  1.00 73.80  ? 219 LYS A CB  1 
ATOM   1735  C CG  . LYS A 1 219 ? -58.314 -13.900 36.402  1.00 81.85  ? 219 LYS A CG  1 
ATOM   1736  C CD  . LYS A 1 219 ? -58.082 -13.340 37.797  1.00 90.61  ? 219 LYS A CD  1 
ATOM   1737  C CE  . LYS A 1 219 ? -58.933 -14.010 38.865  1.00 88.99  ? 219 LYS A CE  1 
ATOM   1738  N NZ  . LYS A 1 219 ? -58.958 -15.489 38.741  1.00 84.06  ? 219 LYS A NZ  1 
ATOM   1739  N N   . PRO A 1 220 ? -57.423 -12.001 32.248  1.00 54.12  ? 220 PRO A N   1 
ATOM   1740  C CA  . PRO A 1 220 ? -57.536 -13.414 31.887  1.00 54.28  ? 220 PRO A CA  1 
ATOM   1741  C C   . PRO A 1 220 ? -56.269 -14.093 31.369  1.00 53.15  ? 220 PRO A C   1 
ATOM   1742  O O   . PRO A 1 220 ? -56.345 -15.032 30.568  1.00 55.89  ? 220 PRO A O   1 
ATOM   1743  C CB  . PRO A 1 220 ? -58.531 -13.305 30.727  1.00 58.90  ? 220 PRO A CB  1 
ATOM   1744  C CG  . PRO A 1 220 ? -58.083 -12.028 30.003  1.00 62.33  ? 220 PRO A CG  1 
ATOM   1745  C CD  . PRO A 1 220 ? -57.598 -11.099 31.099  1.00 56.96  ? 220 PRO A CD  1 
ATOM   1746  N N   . TYR A 1 221 ? -55.099 -13.635 31.817  1.00 45.36  ? 221 TYR A N   1 
ATOM   1747  C CA  . TYR A 1 221 ? -53.871 -14.253 31.356  1.00 42.20  ? 221 TYR A CA  1 
ATOM   1748  C C   . TYR A 1 221 ? -53.892 -15.752 31.684  1.00 41.13  ? 221 TYR A C   1 
ATOM   1749  O O   . TYR A 1 221 ? -53.340 -16.562 30.935  1.00 42.32  ? 221 TYR A O   1 
ATOM   1750  C CB  . TYR A 1 221 ? -52.623 -13.543 31.904  1.00 35.39  ? 221 TYR A CB  1 
ATOM   1751  C CG  . TYR A 1 221 ? -51.379 -13.984 31.166  1.00 35.73  ? 221 TYR A CG  1 
ATOM   1752  C CD1 . TYR A 1 221 ? -51.136 -13.559 29.860  1.00 35.85  ? 221 TYR A CD1 1 
ATOM   1753  C CD2 . TYR A 1 221 ? -50.499 -14.905 31.712  1.00 34.92  ? 221 TYR A CD2 1 
ATOM   1754  C CE1 . TYR A 1 221 ? -50.043 -13.999 29.132  1.00 34.85  ? 221 TYR A CE1 1 
ATOM   1755  C CE2 . TYR A 1 221 ? -49.394 -15.358 31.002  1.00 35.81  ? 221 TYR A CE2 1 
ATOM   1756  C CZ  . TYR A 1 221 ? -49.168 -14.906 29.707  1.00 38.18  ? 221 TYR A CZ  1 
ATOM   1757  O OH  . TYR A 1 221 ? -48.089 -15.326 28.954  1.00 41.08  ? 221 TYR A OH  1 
ATOM   1758  N N   . ASP A 1 222 ? -54.505 -16.119 32.820  1.00 38.56  ? 222 ASP A N   1 
ATOM   1759  C CA  . ASP A 1 222 ? -54.681 -17.514 33.192  1.00 39.82  ? 222 ASP A CA  1 
ATOM   1760  C C   . ASP A 1 222 ? -55.255 -18.291 32.005  1.00 41.14  ? 222 ASP A C   1 
ATOM   1761  O O   . ASP A 1 222 ? -54.786 -19.391 31.704  1.00 44.34  ? 222 ASP A O   1 
ATOM   1762  C CB  . ASP A 1 222 ? -55.540 -17.656 34.462  1.00 44.14  ? 222 ASP A CB  1 
ATOM   1763  C CG  . ASP A 1 222 ? -56.966 -17.082 34.414  1.00 49.49  ? 222 ASP A CG  1 
ATOM   1764  O OD1 . ASP A 1 222 ? -57.178 -16.016 33.763  1.00 54.53  ? 222 ASP A OD1 1 
ATOM   1765  O OD2 . ASP A 1 222 ? -57.870 -17.665 35.080  1.00 50.25  ? 222 ASP A OD2 1 
ATOM   1766  N N   . ASP A 1 223 ? -56.264 -17.726 31.325  1.00 34.65  ? 223 ASP A N   1 
ATOM   1767  C CA  . ASP A 1 223 ? -56.936 -18.436 30.247  1.00 40.32  ? 223 ASP A CA  1 
ATOM   1768  C C   . ASP A 1 223 ? -56.078 -18.433 28.986  1.00 39.71  ? 223 ASP A C   1 
ATOM   1769  O O   . ASP A 1 223 ? -56.007 -19.439 28.288  1.00 47.21  ? 223 ASP A O   1 
ATOM   1770  C CB  . ASP A 1 223 ? -58.328 -17.851 29.978  1.00 47.25  ? 223 ASP A CB  1 
ATOM   1771  C CG  . ASP A 1 223 ? -59.410 -18.357 30.938  1.00 53.54  ? 223 ASP A CG  1 
ATOM   1772  O OD1 . ASP A 1 223 ? -59.207 -19.423 31.570  1.00 56.75  ? 223 ASP A OD1 1 
ATOM   1773  O OD2 . ASP A 1 223 ? -60.441 -17.682 31.083  1.00 55.63  ? 223 ASP A OD2 1 
ATOM   1774  N N   . VAL A 1 224 ? -55.449 -17.286 28.703  1.00 39.85  ? 224 VAL A N   1 
ATOM   1775  C CA  . VAL A 1 224 ? -54.451 -17.141 27.656  1.00 41.89  ? 224 VAL A CA  1 
ATOM   1776  C C   . VAL A 1 224 ? -53.420 -18.261 27.751  1.00 46.91  ? 224 VAL A C   1 
ATOM   1777  O O   . VAL A 1 224 ? -53.040 -18.816 26.728  1.00 49.58  ? 224 VAL A O   1 
ATOM   1778  C CB  . VAL A 1 224 ? -53.718 -15.789 27.772  1.00 46.22  ? 224 VAL A CB  1 
ATOM   1779  C CG1 . VAL A 1 224 ? -52.579 -15.684 26.773  1.00 48.43  ? 224 VAL A CG1 1 
ATOM   1780  C CG2 . VAL A 1 224 ? -54.638 -14.595 27.618  1.00 48.09  ? 224 VAL A CG2 1 
ATOM   1781  N N   . ALA A 1 225 ? -52.927 -18.526 28.975  1.00 49.27  ? 225 ALA A N   1 
ATOM   1782  C CA  . ALA A 1 225 ? -51.876 -19.504 29.231  1.00 49.84  ? 225 ALA A CA  1 
ATOM   1783  C C   . ALA A 1 225 ? -52.366 -20.930 28.997  1.00 50.12  ? 225 ALA A C   1 
ATOM   1784  O O   . ALA A 1 225 ? -51.680 -21.712 28.337  1.00 43.74  ? 225 ALA A O   1 
ATOM   1785  C CB  . ALA A 1 225 ? -51.393 -19.371 30.654  1.00 54.62  ? 225 ALA A CB  1 
ATOM   1786  N N   . ARG A 1 226 ? -53.525 -21.268 29.595  1.00 46.79  ? 226 ARG A N   1 
ATOM   1787  C CA  . ARG A 1 226 ? -54.174 -22.565 29.386  1.00 42.52  ? 226 ARG A CA  1 
ATOM   1788  C C   . ARG A 1 226 ? -54.322 -22.854 27.895  1.00 38.60  ? 226 ARG A C   1 
ATOM   1789  O O   . ARG A 1 226 ? -53.860 -23.875 27.391  1.00 37.44  ? 226 ARG A O   1 
ATOM   1790  C CB  . ARG A 1 226 ? -55.544 -22.599 30.066  1.00 37.09  ? 226 ARG A CB  1 
ATOM   1791  C CG  . ARG A 1 226 ? -55.464 -22.672 31.580  1.00 37.26  ? 226 ARG A CG  1 
ATOM   1792  C CD  . ARG A 1 226 ? -56.730 -22.149 32.223  1.00 39.84  ? 226 ARG A CD  1 
ATOM   1793  N NE  . ARG A 1 226 ? -56.670 -22.102 33.680  1.00 39.82  ? 226 ARG A NE  1 
ATOM   1794  C CZ  . ARG A 1 226 ? -57.185 -21.122 34.419  1.00 44.02  ? 226 ARG A CZ  1 
ATOM   1795  N NH1 . ARG A 1 226 ? -57.870 -20.129 33.863  1.00 37.91  ? 226 ARG A NH1 1 
ATOM   1796  N NH2 . ARG A 1 226 ? -57.024 -21.147 35.729  1.00 46.86  ? 226 ARG A NH2 1 
ATOM   1797  N N   . LEU A 1 227 ? -54.966 -21.936 27.186  1.00 38.13  ? 227 LEU A N   1 
ATOM   1798  C CA  . LEU A 1 227 ? -55.176 -22.137 25.772  1.00 38.62  ? 227 LEU A CA  1 
ATOM   1799  C C   . LEU A 1 227 ? -53.840 -22.355 25.075  1.00 37.54  ? 227 LEU A C   1 
ATOM   1800  O O   . LEU A 1 227 ? -53.665 -23.335 24.362  1.00 45.85  ? 227 LEU A O   1 
ATOM   1801  C CB  . LEU A 1 227 ? -55.880 -20.907 25.207  1.00 40.55  ? 227 LEU A CB  1 
ATOM   1802  C CG  . LEU A 1 227 ? -56.094 -20.949 23.699  1.00 41.01  ? 227 LEU A CG  1 
ATOM   1803  C CD1 . LEU A 1 227 ? -56.912 -22.170 23.301  1.00 38.07  ? 227 LEU A CD1 1 
ATOM   1804  C CD2 . LEU A 1 227 ? -56.760 -19.659 23.244  1.00 46.70  ? 227 LEU A CD2 1 
ATOM   1805  N N   . TYR A 1 228 ? -52.905 -21.432 25.289  1.00 35.29  ? 228 TYR A N   1 
ATOM   1806  C CA  . TYR A 1 228 ? -51.646 -21.418 24.565  1.00 38.41  ? 228 TYR A CA  1 
ATOM   1807  C C   . TYR A 1 228 ? -50.950 -22.760 24.738  1.00 37.69  ? 228 TYR A C   1 
ATOM   1808  O O   . TYR A 1 228 ? -50.395 -23.300 23.789  1.00 36.52  ? 228 TYR A O   1 
ATOM   1809  C CB  . TYR A 1 228 ? -50.753 -20.255 25.036  1.00 43.83  ? 228 TYR A CB  1 
ATOM   1810  C CG  . TYR A 1 228 ? -49.419 -20.177 24.342  1.00 42.35  ? 228 TYR A CG  1 
ATOM   1811  C CD1 . TYR A 1 228 ? -48.430 -21.101 24.616  1.00 46.82  ? 228 TYR A CD1 1 
ATOM   1812  C CD2 . TYR A 1 228 ? -49.161 -19.233 23.371  1.00 47.17  ? 228 TYR A CD2 1 
ATOM   1813  C CE1 . TYR A 1 228 ? -47.213 -21.083 23.963  1.00 47.16  ? 228 TYR A CE1 1 
ATOM   1814  C CE2 . TYR A 1 228 ? -47.946 -19.191 22.706  1.00 48.63  ? 228 TYR A CE2 1 
ATOM   1815  C CZ  . TYR A 1 228 ? -46.967 -20.122 22.999  1.00 54.99  ? 228 TYR A CZ  1 
ATOM   1816  O OH  . TYR A 1 228 ? -45.752 -20.127 22.344  1.00 62.19  ? 228 TYR A OH  1 
ATOM   1817  N N   . PHE A 1 229 ? -50.952 -23.288 25.960  1.00 36.55  ? 229 PHE A N   1 
ATOM   1818  C CA  . PHE A 1 229 ? -50.196 -24.501 26.223  1.00 41.91  ? 229 PHE A CA  1 
ATOM   1819  C C   . PHE A 1 229 ? -50.870 -25.681 25.548  1.00 40.48  ? 229 PHE A C   1 
ATOM   1820  O O   . PHE A 1 229 ? -50.196 -26.572 25.052  1.00 44.85  ? 229 PHE A O   1 
ATOM   1821  C CB  . PHE A 1 229 ? -50.082 -24.766 27.729  1.00 43.18  ? 229 PHE A CB  1 
ATOM   1822  C CG  . PHE A 1 229 ? -49.218 -23.792 28.494  1.00 40.34  ? 229 PHE A CG  1 
ATOM   1823  C CD1 . PHE A 1 229 ? -48.157 -23.124 27.870  1.00 41.87  ? 229 PHE A CD1 1 
ATOM   1824  C CD2 . PHE A 1 229 ? -49.484 -23.524 29.832  1.00 38.08  ? 229 PHE A CD2 1 
ATOM   1825  C CE1 . PHE A 1 229 ? -47.364 -22.232 28.575  1.00 39.65  ? 229 PHE A CE1 1 
ATOM   1826  C CE2 . PHE A 1 229 ? -48.692 -22.630 30.540  1.00 40.65  ? 229 PHE A CE2 1 
ATOM   1827  C CZ  . PHE A 1 229 ? -47.635 -21.991 29.910  1.00 42.53  ? 229 PHE A CZ  1 
ATOM   1828  N N   . ILE A 1 230 ? -52.203 -25.667 25.549  1.00 39.71  ? 230 ILE A N   1 
ATOM   1829  C CA  . ILE A 1 230 ? -52.998 -26.707 24.909  1.00 37.32  ? 230 ILE A CA  1 
ATOM   1830  C C   . ILE A 1 230 ? -52.756 -26.687 23.402  1.00 34.25  ? 230 ILE A C   1 
ATOM   1831  O O   . ILE A 1 230 ? -52.444 -27.717 22.832  1.00 36.30  ? 230 ILE A O   1 
ATOM   1832  C CB  . ILE A 1 230 ? -54.480 -26.580 25.333  1.00 38.92  ? 230 ILE A CB  1 
ATOM   1833  C CG1 . ILE A 1 230 ? -54.674 -27.082 26.777  1.00 39.25  ? 230 ILE A CG1 1 
ATOM   1834  C CG2 . ILE A 1 230 ? -55.404 -27.291 24.357  1.00 40.10  ? 230 ILE A CG2 1 
ATOM   1835  C CD1 . ILE A 1 230 ? -55.896 -26.540 27.474  1.00 40.16  ? 230 ILE A CD1 1 
ATOM   1836  N N   . LEU A 1 231 ? -52.803 -25.513 22.773  1.00 37.51  ? 231 LEU A N   1 
ATOM   1837  C CA  . LEU A 1 231 ? -52.587 -25.393 21.331  1.00 38.90  ? 231 LEU A CA  1 
ATOM   1838  C C   . LEU A 1 231 ? -51.191 -25.870 20.931  1.00 35.48  ? 231 LEU A C   1 
ATOM   1839  O O   . LEU A 1 231 ? -51.018 -26.508 19.896  1.00 36.90  ? 231 LEU A O   1 
ATOM   1840  C CB  . LEU A 1 231 ? -52.803 -23.938 20.895  1.00 40.12  ? 231 LEU A CB  1 
ATOM   1841  C CG  . LEU A 1 231 ? -54.211 -23.381 21.126  1.00 42.56  ? 231 LEU A CG  1 
ATOM   1842  C CD1 . LEU A 1 231 ? -54.476 -22.132 20.300  1.00 43.50  ? 231 LEU A CD1 1 
ATOM   1843  C CD2 . LEU A 1 231 ? -55.263 -24.427 20.819  1.00 44.50  ? 231 LEU A CD2 1 
ATOM   1844  N N   . HIS A 1 232 ? -50.194 -25.588 21.768  1.00 37.14  ? 232 HIS A N   1 
ATOM   1845  C CA  . HIS A 1 232 ? -48.821 -25.875 21.403  1.00 39.92  ? 232 HIS A CA  1 
ATOM   1846  C C   . HIS A 1 232 ? -48.376 -27.219 21.969  1.00 41.90  ? 232 HIS A C   1 
ATOM   1847  O O   . HIS A 1 232 ? -47.204 -27.569 21.847  1.00 51.15  ? 232 HIS A O   1 
ATOM   1848  C CB  . HIS A 1 232 ? -47.897 -24.724 21.850  1.00 39.93  ? 232 HIS A CB  1 
ATOM   1849  C CG  . HIS A 1 232 ? -48.104 -23.425 21.135  1.00 36.93  ? 232 HIS A CG  1 
ATOM   1850  N ND1 . HIS A 1 232 ? -49.108 -22.542 21.447  1.00 43.32  ? 232 HIS A ND1 1 
ATOM   1851  C CD2 . HIS A 1 232 ? -47.393 -22.862 20.114  1.00 41.29  ? 232 HIS A CD2 1 
ATOM   1852  C CE1 . HIS A 1 232 ? -49.034 -21.475 20.646  1.00 46.77  ? 232 HIS A CE1 1 
ATOM   1853  N NE2 . HIS A 1 232 ? -47.964 -21.653 19.806  1.00 46.10  ? 232 HIS A NE2 1 
ATOM   1854  N N   . SER A 1 233 ? -49.313 -28.011 22.505  1.00 42.13  ? 233 SER A N   1 
ATOM   1855  C CA  . SER A 1 233 ? -48.980 -29.243 23.214  1.00 40.94  ? 233 SER A CA  1 
ATOM   1856  C C   . SER A 1 233 ? -48.340 -30.314 22.319  1.00 41.81  ? 233 SER A C   1 
ATOM   1857  O O   . SER A 1 233 ? -47.439 -31.028 22.771  1.00 38.99  ? 233 SER A O   1 
ATOM   1858  C CB  . SER A 1 233 ? -50.192 -29.772 23.920  1.00 42.84  ? 233 SER A CB  1 
ATOM   1859  O OG  . SER A 1 233 ? -51.267 -29.919 23.002  1.00 44.42  ? 233 SER A OG  1 
ATOM   1860  N N   . ASP A 1 234 ? -48.826 -30.496 21.082  1.00 40.88  ? 234 ASP A N   1 
ATOM   1861  C CA  . ASP A 1 234 ? -48.181 -31.440 20.181  1.00 51.10  ? 234 ASP A CA  1 
ATOM   1862  C C   . ASP A 1 234 ? -48.476 -31.007 18.754  1.00 51.92  ? 234 ASP A C   1 
ATOM   1863  O O   . ASP A 1 234 ? -49.351 -30.154 18.550  1.00 54.70  ? 234 ASP A O   1 
ATOM   1864  C CB  . ASP A 1 234 ? -48.560 -32.912 20.461  1.00 63.63  ? 234 ASP A CB  1 
ATOM   1865  C CG  . ASP A 1 234 ? -47.466 -33.959 20.173  1.00 82.54  ? 234 ASP A CG  1 
ATOM   1866  O OD1 . ASP A 1 234 ? -46.283 -33.744 20.593  1.00 89.82  ? 234 ASP A OD1 1 
ATOM   1867  O OD2 . ASP A 1 234 ? -47.784 -35.035 19.550  1.00 92.41  ? 234 ASP A OD2 1 
ATOM   1868  N N   . HIS A 1 235 ? -47.640 -31.529 17.825  1.00 50.12  ? 235 HIS A N   1 
ATOM   1869  C CA  . HIS A 1 235 ? -47.809 -31.376 16.385  1.00 53.13  ? 235 HIS A CA  1 
ATOM   1870  C C   . HIS A 1 235 ? -47.098 -32.522 15.669  1.00 52.32  ? 235 HIS A C   1 
ATOM   1871  O O   . HIS A 1 235 ? -46.181 -32.307 14.880  1.00 50.73  ? 235 HIS A O   1 
ATOM   1872  C CB  . HIS A 1 235 ? -47.307 -30.009 15.905  1.00 53.21  ? 235 HIS A CB  1 
ATOM   1873  C CG  . HIS A 1 235 ? -48.164 -29.373 14.856  1.00 58.35  ? 235 HIS A CG  1 
ATOM   1874  N ND1 . HIS A 1 235 ? -47.719 -29.025 13.611  1.00 63.80  ? 235 HIS A ND1 1 
ATOM   1875  C CD2 . HIS A 1 235 ? -49.478 -29.014 14.924  1.00 63.52  ? 235 HIS A CD2 1 
ATOM   1876  C CE1 . HIS A 1 235 ? -48.720 -28.466 12.936  1.00 67.42  ? 235 HIS A CE1 1 
ATOM   1877  N NE2 . HIS A 1 235 ? -49.827 -28.457 13.726  1.00 68.81  ? 235 HIS A NE2 1 
ATOM   1878  N N   . GLU A 1 236 ? -47.602 -33.727 15.949  1.00 53.83  ? 236 GLU A N   1 
ATOM   1879  C CA  . GLU A 1 236 ? -46.988 -35.017 15.677  1.00 55.23  ? 236 GLU A CA  1 
ATOM   1880  C C   . GLU A 1 236 ? -45.488 -34.979 15.966  1.00 53.01  ? 236 GLU A C   1 
ATOM   1881  O O   . GLU A 1 236 ? -44.982 -33.974 16.448  1.00 59.49  ? 236 GLU A O   1 
ATOM   1882  C CB  . GLU A 1 236 ? -47.402 -35.540 14.300  1.00 65.69  ? 236 GLU A CB  1 
ATOM   1883  C CG  . GLU A 1 236 ? -47.009 -34.687 13.103  1.00 73.71  ? 236 GLU A CG  1 
ATOM   1884  C CD  . GLU A 1 236 ? -47.149 -35.443 11.789  1.00 79.73  ? 236 GLU A CD  1 
ATOM   1885  O OE1 . GLU A 1 236 ? -48.276 -35.895 11.509  1.00 85.08  ? 236 GLU A OE1 1 
ATOM   1886  O OE2 . GLU A 1 236 ? -46.122 -35.629 11.078  1.00 68.49  ? 236 GLU A OE2 1 
ATOM   1887  N N   . SER A 1 237 ? -44.799 -36.103 15.711  1.00 49.64  ? 237 SER A N   1 
ATOM   1888  C CA  . SER A 1 237 ? -43.427 -36.329 16.146  1.00 50.12  ? 237 SER A CA  1 
ATOM   1889  C C   . SER A 1 237 ? -42.386 -36.009 15.058  1.00 50.02  ? 237 SER A C   1 
ATOM   1890  O O   . SER A 1 237 ? -41.212 -36.365 15.203  1.00 40.73  ? 237 SER A O   1 
ATOM   1891  C CB  . SER A 1 237 ? -43.261 -37.756 16.675  1.00 50.24  ? 237 SER A CB  1 
ATOM   1892  O OG  . SER A 1 237 ? -43.388 -38.714 15.626  1.00 45.60  ? 237 SER A OG  1 
ATOM   1893  N N   . GLY A 1 238 ? -42.779 -35.296 13.993  1.00 49.70  ? 238 GLY A N   1 
ATOM   1894  C CA  . GLY A 1 238 ? -41.865 -35.020 12.897  1.00 49.54  ? 238 GLY A CA  1 
ATOM   1895  C C   . GLY A 1 238 ? -41.159 -33.665 13.032  1.00 48.56  ? 238 GLY A C   1 
ATOM   1896  O O   . GLY A 1 238 ? -40.107 -33.437 12.413  1.00 42.90  ? 238 GLY A O   1 
ATOM   1897  N N   . ASN A 1 239 ? -41.762 -32.768 13.831  1.00 41.02  ? 239 ASN A N   1 
ATOM   1898  C CA  . ASN A 1 239 ? -41.189 -31.453 14.050  1.00 41.64  ? 239 ASN A CA  1 
ATOM   1899  C C   . ASN A 1 239 ? -39.865 -31.611 14.807  1.00 40.70  ? 239 ASN A C   1 
ATOM   1900  O O   . ASN A 1 239 ? -39.629 -32.602 15.505  1.00 36.41  ? 239 ASN A O   1 
ATOM   1901  C CB  . ASN A 1 239 ? -42.219 -30.538 14.718  1.00 43.78  ? 239 ASN A CB  1 
ATOM   1902  C CG  . ASN A 1 239 ? -42.555 -30.937 16.141  1.00 47.52  ? 239 ASN A CG  1 
ATOM   1903  O OD1 . ASN A 1 239 ? -41.802 -30.648 17.074  1.00 40.67  ? 239 ASN A OD1 1 
ATOM   1904  N ND2 . ASN A 1 239 ? -43.694 -31.589 16.315  1.00 42.42  ? 239 ASN A ND2 1 
ATOM   1905  N N   . VAL A 1 240 ? -39.000 -30.607 14.662  1.00 39.97  ? 240 VAL A N   1 
ATOM   1906  C CA  . VAL A 1 240 ? -37.627 -30.720 15.115  1.00 41.41  ? 240 VAL A CA  1 
ATOM   1907  C C   . VAL A 1 240 ? -37.571 -31.011 16.609  1.00 36.70  ? 240 VAL A C   1 
ATOM   1908  O O   . VAL A 1 240 ? -36.819 -31.888 16.998  1.00 37.03  ? 240 VAL A O   1 
ATOM   1909  C CB  . VAL A 1 240 ? -36.795 -29.479 14.750  1.00 42.83  ? 240 VAL A CB  1 
ATOM   1910  C CG1 . VAL A 1 240 ? -35.463 -29.443 15.507  1.00 42.49  ? 240 VAL A CG1 1 
ATOM   1911  C CG2 . VAL A 1 240 ? -36.552 -29.421 13.250  1.00 42.59  ? 240 VAL A CG2 1 
ATOM   1912  N N   . SER A 1 241 ? -38.353 -30.283 17.418  1.00 41.73  ? 241 SER A N   1 
ATOM   1913  C CA  . SER A 1 241 ? -38.307 -30.410 18.879  1.00 41.09  ? 241 SER A CA  1 
ATOM   1914  C C   . SER A 1 241 ? -38.812 -31.786 19.315  1.00 40.44  ? 241 SER A C   1 
ATOM   1915  O O   . SER A 1 241 ? -38.112 -32.501 20.028  1.00 38.04  ? 241 SER A O   1 
ATOM   1916  C CB  . SER A 1 241 ? -39.010 -29.245 19.622  1.00 39.97  ? 241 SER A CB  1 
ATOM   1917  O OG  . SER A 1 241 ? -40.386 -29.122 19.310  1.00 36.96  ? 241 SER A OG  1 
ATOM   1918  N N   . ALA A 1 242 ? -39.990 -32.205 18.829  1.00 41.56  ? 242 ALA A N   1 
ATOM   1919  C CA  . ALA A 1 242 ? -40.520 -33.519 19.175  1.00 37.34  ? 242 ALA A CA  1 
ATOM   1920  C C   . ALA A 1 242 ? -39.593 -34.621 18.667  1.00 37.59  ? 242 ALA A C   1 
ATOM   1921  O O   . ALA A 1 242 ? -39.286 -35.547 19.416  1.00 44.21  ? 242 ALA A O   1 
ATOM   1922  C CB  . ALA A 1 242 ? -41.903 -33.679 18.629  1.00 36.31  ? 242 ALA A CB  1 
ATOM   1923  N N   . HIS A 1 243 ? -39.144 -34.506 17.409  1.00 35.64  ? 243 HIS A N   1 
ATOM   1924  C CA  . HIS A 1 243 ? -38.280 -35.495 16.776  1.00 32.19  ? 243 HIS A CA  1 
ATOM   1925  C C   . HIS A 1 243 ? -36.955 -35.601 17.515  1.00 34.77  ? 243 HIS A C   1 
ATOM   1926  O O   . HIS A 1 243 ? -36.417 -36.703 17.617  1.00 39.01  ? 243 HIS A O   1 
ATOM   1927  C CB  . HIS A 1 243 ? -38.032 -35.109 15.315  1.00 36.04  ? 243 HIS A CB  1 
ATOM   1928  C CG  . HIS A 1 243 ? -37.185 -36.048 14.503  1.00 39.39  ? 243 HIS A CG  1 
ATOM   1929  N ND1 . HIS A 1 243 ? -36.629 -35.689 13.280  1.00 44.04  ? 243 HIS A ND1 1 
ATOM   1930  C CD2 . HIS A 1 243 ? -36.796 -37.339 14.754  1.00 40.83  ? 243 HIS A CD2 1 
ATOM   1931  C CE1 . HIS A 1 243 ? -35.941 -36.727 12.793  1.00 48.16  ? 243 HIS A CE1 1 
ATOM   1932  N NE2 . HIS A 1 243 ? -36.038 -37.772 13.695  1.00 46.51  ? 243 HIS A NE2 1 
ATOM   1933  N N   . THR A 1 244 ? -36.404 -34.465 17.988  1.00 31.09  ? 244 THR A N   1 
ATOM   1934  C CA  . THR A 1 244 ? -35.143 -34.508 18.715  1.00 31.62  ? 244 THR A CA  1 
ATOM   1935  C C   . THR A 1 244 ? -35.262 -35.313 20.022  1.00 32.87  ? 244 THR A C   1 
ATOM   1936  O O   . THR A 1 244 ? -34.412 -36.155 20.346  1.00 31.28  ? 244 THR A O   1 
ATOM   1937  C CB  . THR A 1 244 ? -34.626 -33.099 19.017  1.00 32.67  ? 244 THR A CB  1 
ATOM   1938  O OG1 . THR A 1 244 ? -34.421 -32.352 17.816  1.00 30.12  ? 244 THR A OG1 1 
ATOM   1939  C CG2 . THR A 1 244 ? -33.321 -33.140 19.783  1.00 34.63  ? 244 THR A CG2 1 
ATOM   1940  N N   . ALA A 1 245 ? -36.321 -35.032 20.794  1.00 32.69  ? 245 ALA A N   1 
ATOM   1941  C CA  . ALA A 1 245 ? -36.529 -35.714 22.060  1.00 32.74  ? 245 ALA A CA  1 
ATOM   1942  C C   . ALA A 1 245 ? -36.702 -37.199 21.771  1.00 39.18  ? 245 ALA A C   1 
ATOM   1943  O O   . ALA A 1 245 ? -36.036 -38.043 22.358  1.00 37.79  ? 245 ALA A O   1 
ATOM   1944  C CB  . ALA A 1 245 ? -37.732 -35.143 22.786  1.00 34.48  ? 245 ALA A CB  1 
ATOM   1945  N N   . HIS A 1 246 ? -37.577 -37.502 20.811  1.00 39.76  ? 246 HIS A N   1 
ATOM   1946  C CA  . HIS A 1 246 ? -37.767 -38.878 20.397  1.00 41.28  ? 246 HIS A CA  1 
ATOM   1947  C C   . HIS A 1 246 ? -36.406 -39.526 20.120  1.00 37.39  ? 246 HIS A C   1 
ATOM   1948  O O   . HIS A 1 246 ? -36.123 -40.614 20.599  1.00 40.91  ? 246 HIS A O   1 
ATOM   1949  C CB  . HIS A 1 246 ? -38.726 -38.932 19.187  1.00 44.82  ? 246 HIS A CB  1 
ATOM   1950  C CG  . HIS A 1 246 ? -38.871 -40.303 18.603  1.00 49.68  ? 246 HIS A CG  1 
ATOM   1951  N ND1 . HIS A 1 246 ? -39.545 -41.344 19.221  1.00 48.78  ? 246 HIS A ND1 1 
ATOM   1952  C CD2 . HIS A 1 246 ? -38.317 -40.795 17.459  1.00 46.54  ? 246 HIS A CD2 1 
ATOM   1953  C CE1 . HIS A 1 246 ? -39.434 -42.434 18.469  1.00 45.22  ? 246 HIS A CE1 1 
ATOM   1954  N NE2 . HIS A 1 246 ? -38.669 -42.113 17.366  1.00 45.22  ? 246 HIS A NE2 1 
ATOM   1955  N N   . LEU A 1 247 ? -35.555 -38.845 19.346  1.00 38.02  ? 247 LEU A N   1 
ATOM   1956  C CA  . LEU A 1 247 ? -34.313 -39.428 18.857  1.00 34.02  ? 247 LEU A CA  1 
ATOM   1957  C C   . LEU A 1 247 ? -33.375 -39.665 20.031  1.00 36.51  ? 247 LEU A C   1 
ATOM   1958  O O   . LEU A 1 247 ? -32.889 -40.777 20.219  1.00 42.61  ? 247 LEU A O   1 
ATOM   1959  C CB  . LEU A 1 247 ? -33.727 -38.482 17.804  1.00 37.47  ? 247 LEU A CB  1 
ATOM   1960  C CG  . LEU A 1 247 ? -32.241 -38.600 17.439  1.00 39.70  ? 247 LEU A CG  1 
ATOM   1961  C CD1 . LEU A 1 247 ? -31.769 -40.029 17.209  1.00 45.63  ? 247 LEU A CD1 1 
ATOM   1962  C CD2 . LEU A 1 247 ? -31.965 -37.800 16.173  1.00 39.16  ? 247 LEU A CD2 1 
ATOM   1963  N N   . VAL A 1 248 ? -33.163 -38.634 20.851  1.00 33.02  ? 248 VAL A N   1 
ATOM   1964  C CA  . VAL A 1 248 ? -32.309 -38.761 22.010  1.00 31.53  ? 248 VAL A CA  1 
ATOM   1965  C C   . VAL A 1 248 ? -32.826 -39.876 22.922  1.00 35.13  ? 248 VAL A C   1 
ATOM   1966  O O   . VAL A 1 248 ? -32.058 -40.711 23.437  1.00 37.55  ? 248 VAL A O   1 
ATOM   1967  C CB  . VAL A 1 248 ? -32.215 -37.407 22.744  1.00 32.54  ? 248 VAL A CB  1 
ATOM   1968  C CG1 . VAL A 1 248 ? -31.611 -37.544 24.138  1.00 35.54  ? 248 VAL A CG1 1 
ATOM   1969  C CG2 . VAL A 1 248 ? -31.438 -36.387 21.924  1.00 30.12  ? 248 VAL A CG2 1 
ATOM   1970  N N   . ALA A 1 249 ? -34.141 -39.890 23.152  1.00 33.31  ? 249 ALA A N   1 
ATOM   1971  C CA  . ALA A 1 249 ? -34.721 -40.822 24.111  1.00 37.72  ? 249 ALA A CA  1 
ATOM   1972  C C   . ALA A 1 249 ? -34.622 -42.267 23.607  1.00 38.01  ? 249 ALA A C   1 
ATOM   1973  O O   . ALA A 1 249 ? -34.573 -43.203 24.410  1.00 43.35  ? 249 ALA A O   1 
ATOM   1974  C CB  . ALA A 1 249 ? -36.149 -40.428 24.431  1.00 39.40  ? 249 ALA A CB  1 
ATOM   1975  N N   . SER A 1 250 ? -34.533 -42.452 22.288  1.00 35.50  ? 250 SER A N   1 
ATOM   1976  C CA  . SER A 1 250 ? -34.432 -43.779 21.697  1.00 33.69  ? 250 SER A CA  1 
ATOM   1977  C C   . SER A 1 250 ? -33.109 -44.473 22.051  1.00 35.54  ? 250 SER A C   1 
ATOM   1978  O O   . SER A 1 250 ? -33.006 -45.695 21.938  1.00 38.98  ? 250 SER A O   1 
ATOM   1979  C CB  . SER A 1 250 ? -34.634 -43.690 20.218  1.00 29.52  ? 250 SER A CB  1 
ATOM   1980  O OG  . SER A 1 250 ? -33.487 -43.163 19.599  1.00 31.82  ? 250 SER A OG  1 
ATOM   1981  N N   . ALA A 1 251 ? -32.110 -43.713 22.529  1.00 35.61  ? 251 ALA A N   1 
ATOM   1982  C CA  . ALA A 1 251 ? -30.876 -44.276 23.075  1.00 33.04  ? 251 ALA A CA  1 
ATOM   1983  C C   . ALA A 1 251 ? -31.002 -44.605 24.570  1.00 33.29  ? 251 ALA A C   1 
ATOM   1984  O O   . ALA A 1 251 ? -30.012 -45.036 25.190  1.00 29.09  ? 251 ALA A O   1 
ATOM   1985  C CB  . ALA A 1 251 ? -29.751 -43.288 22.841  1.00 36.38  ? 251 ALA A CB  1 
ATOM   1986  N N   . LEU A 1 252 ? -32.217 -44.392 25.124  1.00 31.57  ? 252 LEU A N   1 
ATOM   1987  C CA  . LEU A 1 252 ? -32.576 -44.555 26.527  1.00 33.01  ? 252 LEU A CA  1 
ATOM   1988  C C   . LEU A 1 252 ? -31.970 -43.448 27.395  1.00 38.16  ? 252 LEU A C   1 
ATOM   1989  O O   . LEU A 1 252 ? -31.713 -43.661 28.582  1.00 43.74  ? 252 LEU A O   1 
ATOM   1990  C CB  . LEU A 1 252 ? -32.129 -45.925 27.049  1.00 36.27  ? 252 LEU A CB  1 
ATOM   1991  C CG  . LEU A 1 252 ? -32.761 -47.143 26.385  1.00 39.27  ? 252 LEU A CG  1 
ATOM   1992  C CD1 . LEU A 1 252 ? -32.250 -48.403 27.016  1.00 39.25  ? 252 LEU A CD1 1 
ATOM   1993  C CD2 . LEU A 1 252 ? -34.264 -47.095 26.477  1.00 42.03  ? 252 LEU A CD2 1 
ATOM   1994  N N   . SER A 1 253 ? -31.733 -42.265 26.822  1.00 42.94  ? 253 SER A N   1 
ATOM   1995  C CA  . SER A 1 253 ? -31.488 -41.075 27.625  1.00 44.46  ? 253 SER A CA  1 
ATOM   1996  C C   . SER A 1 253 ? -32.808 -40.733 28.313  1.00 47.55  ? 253 SER A C   1 
ATOM   1997  O O   . SER A 1 253 ? -33.868 -40.890 27.697  1.00 58.29  ? 253 SER A O   1 
ATOM   1998  C CB  . SER A 1 253 ? -30.952 -39.913 26.790  1.00 43.68  ? 253 SER A CB  1 
ATOM   1999  O OG  . SER A 1 253 ? -29.615 -40.162 26.349  1.00 41.95  ? 253 SER A OG  1 
ATOM   2000  N N   . ASP A 1 254 ? -32.743 -40.293 29.579  1.00 42.50  ? 254 ASP A N   1 
ATOM   2001  C CA  . ASP A 1 254 ? -33.935 -39.902 30.311  1.00 40.49  ? 254 ASP A CA  1 
ATOM   2002  C C   . ASP A 1 254 ? -34.563 -38.627 29.721  1.00 36.97  ? 254 ASP A C   1 
ATOM   2003  O O   . ASP A 1 254 ? -34.010 -37.971 28.835  1.00 36.78  ? 254 ASP A O   1 
ATOM   2004  C CB  . ASP A 1 254 ? -33.602 -39.722 31.792  1.00 41.31  ? 254 ASP A CB  1 
ATOM   2005  C CG  . ASP A 1 254 ? -32.482 -38.718 32.011  1.00 44.45  ? 254 ASP A CG  1 
ATOM   2006  O OD1 . ASP A 1 254 ? -32.666 -37.529 31.636  1.00 48.49  ? 254 ASP A OD1 1 
ATOM   2007  O OD2 . ASP A 1 254 ? -31.417 -39.136 32.489  1.00 44.51  ? 254 ASP A OD2 1 
ATOM   2008  N N   . ALA A 1 255 ? -35.735 -38.257 30.258  1.00 34.33  ? 255 ALA A N   1 
ATOM   2009  C CA  . ALA A 1 255 ? -36.546 -37.183 29.699  1.00 31.02  ? 255 ALA A CA  1 
ATOM   2010  C C   . ALA A 1 255 ? -35.902 -35.827 29.934  1.00 30.13  ? 255 ALA A C   1 
ATOM   2011  O O   . ALA A 1 255 ? -36.243 -34.873 29.238  1.00 31.22  ? 255 ALA A O   1 
ATOM   2012  C CB  . ALA A 1 255 ? -37.924 -37.213 30.315  1.00 32.85  ? 255 ALA A CB  1 
ATOM   2013  N N   . TYR A 1 256 ? -35.033 -35.727 30.951  1.00 27.91  ? 256 TYR A N   1 
ATOM   2014  C CA  . TYR A 1 256 ? -34.318 -34.489 31.201  1.00 26.35  ? 256 TYR A CA  1 
ATOM   2015  C C   . TYR A 1 256 ? -33.362 -34.204 30.046  1.00 27.13  ? 256 TYR A C   1 
ATOM   2016  O O   . TYR A 1 256 ? -33.385 -33.123 29.466  1.00 32.70  ? 256 TYR A O   1 
ATOM   2017  C CB  . TYR A 1 256 ? -33.658 -34.603 32.571  1.00 27.91  ? 256 TYR A CB  1 
ATOM   2018  C CG  . TYR A 1 256 ? -34.661 -34.619 33.707  1.00 26.86  ? 256 TYR A CG  1 
ATOM   2019  C CD1 . TYR A 1 256 ? -35.267 -33.461 34.109  1.00 25.35  ? 256 TYR A CD1 1 
ATOM   2020  C CD2 . TYR A 1 256 ? -35.035 -35.779 34.353  1.00 29.43  ? 256 TYR A CD2 1 
ATOM   2021  C CE1 . TYR A 1 256 ? -36.184 -33.442 35.140  1.00 29.69  ? 256 TYR A CE1 1 
ATOM   2022  C CE2 . TYR A 1 256 ? -35.919 -35.779 35.421  1.00 29.11  ? 256 TYR A CE2 1 
ATOM   2023  C CZ  . TYR A 1 256 ? -36.525 -34.601 35.806  1.00 29.92  ? 256 TYR A CZ  1 
ATOM   2024  O OH  . TYR A 1 256 ? -37.485 -34.492 36.807  1.00 30.38  ? 256 TYR A OH  1 
ATOM   2025  N N   . TYR A 1 257 ? -32.564 -35.205 29.661  1.00 28.05  ? 257 TYR A N   1 
ATOM   2026  C CA  . TYR A 1 257 ? -31.679 -35.113 28.509  1.00 27.69  ? 257 TYR A CA  1 
ATOM   2027  C C   . TYR A 1 257 ? -32.490 -34.886 27.228  1.00 29.91  ? 257 TYR A C   1 
ATOM   2028  O O   . TYR A 1 257 ? -32.193 -34.009 26.419  1.00 33.47  ? 257 TYR A O   1 
ATOM   2029  C CB  . TYR A 1 257 ? -30.856 -36.402 28.387  1.00 29.01  ? 257 TYR A CB  1 
ATOM   2030  C CG  . TYR A 1 257 ? -29.647 -36.578 29.281  1.00 28.24  ? 257 TYR A CG  1 
ATOM   2031  C CD1 . TYR A 1 257 ? -28.687 -35.580 29.418  1.00 28.81  ? 257 TYR A CD1 1 
ATOM   2032  C CD2 . TYR A 1 257 ? -29.390 -37.799 29.900  1.00 30.30  ? 257 TYR A CD2 1 
ATOM   2033  C CE1 . TYR A 1 257 ? -27.552 -35.762 30.202  1.00 29.52  ? 257 TYR A CE1 1 
ATOM   2034  C CE2 . TYR A 1 257 ? -28.260 -37.994 30.693  1.00 31.22  ? 257 TYR A CE2 1 
ATOM   2035  C CZ  . TYR A 1 257 ? -27.329 -36.973 30.840  1.00 30.59  ? 257 TYR A CZ  1 
ATOM   2036  O OH  . TYR A 1 257 ? -26.203 -37.180 31.624  1.00 34.52  ? 257 TYR A OH  1 
ATOM   2037  N N   . ALA A 1 258 ? -33.550 -35.676 27.046  1.00 29.25  ? 258 ALA A N   1 
ATOM   2038  C CA  . ALA A 1 258 ? -34.344 -35.622 25.830  1.00 29.08  ? 258 ALA A CA  1 
ATOM   2039  C C   . ALA A 1 258 ? -35.017 -34.269 25.634  1.00 30.53  ? 258 ALA A C   1 
ATOM   2040  O O   . ALA A 1 258 ? -35.065 -33.754 24.508  1.00 30.47  ? 258 ALA A O   1 
ATOM   2041  C CB  . ALA A 1 258 ? -35.391 -36.692 25.877  1.00 31.59  ? 258 ALA A CB  1 
ATOM   2042  N N   . TYR A 1 259 ? -35.614 -33.750 26.715  1.00 29.72  ? 259 TYR A N   1 
ATOM   2043  C CA  . TYR A 1 259 ? -36.371 -32.515 26.626  1.00 32.23  ? 259 TYR A CA  1 
ATOM   2044  C C   . TYR A 1 259 ? -35.412 -31.314 26.592  1.00 30.70  ? 259 TYR A C   1 
ATOM   2045  O O   . TYR A 1 259 ? -35.686 -30.327 25.916  1.00 37.31  ? 259 TYR A O   1 
ATOM   2046  C CB  . TYR A 1 259 ? -37.442 -32.412 27.736  1.00 31.61  ? 259 TYR A CB  1 
ATOM   2047  C CG  . TYR A 1 259 ? -38.531 -31.469 27.298  1.00 28.89  ? 259 TYR A CG  1 
ATOM   2048  C CD1 . TYR A 1 259 ? -39.226 -31.743 26.124  1.00 29.79  ? 259 TYR A CD1 1 
ATOM   2049  C CD2 . TYR A 1 259 ? -38.723 -30.231 27.888  1.00 31.09  ? 259 TYR A CD2 1 
ATOM   2050  C CE1 . TYR A 1 259 ? -40.165 -30.871 25.609  1.00 28.55  ? 259 TYR A CE1 1 
ATOM   2051  C CE2 . TYR A 1 259 ? -39.649 -29.321 27.364  1.00 34.68  ? 259 TYR A CE2 1 
ATOM   2052  C CZ  . TYR A 1 259 ? -40.382 -29.653 26.230  1.00 33.35  ? 259 TYR A CZ  1 
ATOM   2053  O OH  . TYR A 1 259 ? -41.332 -28.825 25.655  1.00 40.74  ? 259 TYR A OH  1 
ATOM   2054  N N   . SER A 1 260 ? -34.296 -31.381 27.306  1.00 27.44  ? 260 SER A N   1 
ATOM   2055  C CA  . SER A 1 260 ? -33.246 -30.392 27.130  1.00 32.81  ? 260 SER A CA  1 
ATOM   2056  C C   . SER A 1 260 ? -32.795 -30.298 25.666  1.00 33.87  ? 260 SER A C   1 
ATOM   2057  O O   . SER A 1 260 ? -32.709 -29.194 25.125  1.00 35.89  ? 260 SER A O   1 
ATOM   2058  C CB  . SER A 1 260 ? -32.070 -30.699 28.031  1.00 35.16  ? 260 SER A CB  1 
ATOM   2059  O OG  . SER A 1 260 ? -30.989 -29.804 27.765  1.00 37.75  ? 260 SER A OG  1 
ATOM   2060  N N   . ALA A 1 261 ? -32.486 -31.448 25.033  1.00 35.79  ? 261 ALA A N   1 
ATOM   2061  C CA  . ALA A 1 261 ? -32.096 -31.489 23.625  1.00 36.97  ? 261 ALA A CA  1 
ATOM   2062  C C   . ALA A 1 261 ? -33.172 -30.911 22.705  1.00 36.14  ? 261 ALA A C   1 
ATOM   2063  O O   . ALA A 1 261 ? -32.869 -30.222 21.735  1.00 41.87  ? 261 ALA A O   1 
ATOM   2064  C CB  . ALA A 1 261 ? -31.816 -32.893 23.237  1.00 37.77  ? 261 ALA A CB  1 
ATOM   2065  N N   . ALA A 1 262 ? -34.432 -31.217 22.990  1.00 36.46  ? 262 ALA A N   1 
ATOM   2066  C CA  . ALA A 1 262 ? -35.557 -30.717 22.211  1.00 40.91  ? 262 ALA A CA  1 
ATOM   2067  C C   . ALA A 1 262 ? -35.640 -29.187 22.232  1.00 34.36  ? 262 ALA A C   1 
ATOM   2068  O O   . ALA A 1 262 ? -35.960 -28.562 21.234  1.00 36.42  ? 262 ALA A O   1 
ATOM   2069  C CB  . ALA A 1 262 ? -36.836 -31.337 22.749  1.00 44.88  ? 262 ALA A CB  1 
ATOM   2070  N N   . MET A 1 263 ? -35.375 -28.588 23.390  1.00 35.40  ? 263 MET A N   1 
ATOM   2071  C CA  . MET A 1 263 ? -35.381 -27.140 23.555  1.00 35.11  ? 263 MET A CA  1 
ATOM   2072  C C   . MET A 1 263 ? -34.219 -26.500 22.780  1.00 32.27  ? 263 MET A C   1 
ATOM   2073  O O   . MET A 1 263 ? -34.325 -25.387 22.258  1.00 33.89  ? 263 MET A O   1 
ATOM   2074  C CB  . MET A 1 263 ? -35.306 -26.776 25.046  1.00 32.62  ? 263 MET A CB  1 
ATOM   2075  C CG  . MET A 1 263 ? -36.551 -27.168 25.841  1.00 32.23  ? 263 MET A CG  1 
ATOM   2076  S SD  . MET A 1 263 ? -38.111 -26.524 25.084  1.00 36.31  ? 263 MET A SD  1 
ATOM   2077  C CE  . MET A 1 263 ? -38.494 -27.881 23.965  1.00 38.26  ? 263 MET A CE  1 
ATOM   2078  N N   . CYS A 1 264 ? -33.094 -27.198 22.680  1.00 33.03  ? 264 CYS A N   1 
ATOM   2079  C CA  . CYS A 1 264 ? -32.032 -26.784 21.762  1.00 33.14  ? 264 CYS A CA  1 
ATOM   2080  C C   . CYS A 1 264 ? -32.550 -26.694 20.324  1.00 30.89  ? 264 CYS A C   1 
ATOM   2081  O O   . CYS A 1 264 ? -32.225 -25.730 19.632  1.00 29.31  ? 264 CYS A O   1 
ATOM   2082  C CB  . CYS A 1 264 ? -30.833 -27.720 21.852  1.00 35.53  ? 264 CYS A CB  1 
ATOM   2083  S SG  . CYS A 1 264 ? -30.018 -27.725 23.480  1.00 34.74  ? 264 CYS A SG  1 
ATOM   2084  N N   . GLY A 1 265 ? -33.402 -27.652 19.908  1.00 29.01  ? 265 GLY A N   1 
ATOM   2085  C CA  . GLY A 1 265 ? -34.074 -27.568 18.617  1.00 26.06  ? 265 GLY A CA  1 
ATOM   2086  C C   . GLY A 1 265 ? -35.112 -26.445 18.511  1.00 28.93  ? 265 GLY A C   1 
ATOM   2087  O O   . GLY A 1 265 ? -35.178 -25.719 17.508  1.00 29.60  ? 265 GLY A O   1 
ATOM   2088  N N   . LEU A 1 266 ? -35.960 -26.319 19.537  1.00 27.35  ? 266 LEU A N   1 
ATOM   2089  C CA  . LEU A 1 266 ? -36.996 -25.304 19.534  1.00 29.12  ? 266 LEU A CA  1 
ATOM   2090  C C   . LEU A 1 266 ? -36.416 -23.891 19.463  1.00 35.03  ? 266 LEU A C   1 
ATOM   2091  O O   . LEU A 1 266 ? -37.082 -22.982 18.973  1.00 39.57  ? 266 LEU A O   1 
ATOM   2092  C CB  . LEU A 1 266 ? -37.863 -25.474 20.782  1.00 28.21  ? 266 LEU A CB  1 
ATOM   2093  C CG  . LEU A 1 266 ? -39.111 -24.600 20.812  1.00 27.88  ? 266 LEU A CG  1 
ATOM   2094  C CD1 . LEU A 1 266 ? -40.049 -24.931 19.647  1.00 28.50  ? 266 LEU A CD1 1 
ATOM   2095  C CD2 . LEU A 1 266 ? -39.852 -24.749 22.132  1.00 27.93  ? 266 LEU A CD2 1 
ATOM   2096  N N   . ALA A 1 267 ? -35.183 -23.685 19.945  1.00 38.74  ? 267 ALA A N   1 
ATOM   2097  C CA  . ALA A 1 267 ? -34.591 -22.351 19.949  1.00 41.25  ? 267 ALA A CA  1 
ATOM   2098  C C   . ALA A 1 267 ? -34.158 -21.897 18.543  1.00 43.64  ? 267 ALA A C   1 
ATOM   2099  O O   . ALA A 1 267 ? -33.865 -20.721 18.321  1.00 47.65  ? 267 ALA A O   1 
ATOM   2100  C CB  . ALA A 1 267 ? -33.430 -22.330 20.920  1.00 40.78  ? 267 ALA A CB  1 
ATOM   2101  N N   . GLY A 1 268 ? -34.071 -22.842 17.602  1.00 43.28  ? 268 GLY A N   1 
ATOM   2102  C CA  . GLY A 1 268 ? -33.768 -22.539 16.216  1.00 46.03  ? 268 GLY A CA  1 
ATOM   2103  C C   . GLY A 1 268 ? -34.719 -21.504 15.598  1.00 47.15  ? 268 GLY A C   1 
ATOM   2104  O O   . GLY A 1 268 ? -35.934 -21.515 15.809  1.00 37.79  ? 268 GLY A O   1 
ATOM   2105  N N   . PRO A 1 269 ? -34.201 -20.558 14.789  1.00 50.18  ? 269 PRO A N   1 
ATOM   2106  C CA  . PRO A 1 269 ? -35.052 -19.552 14.151  1.00 50.57  ? 269 PRO A CA  1 
ATOM   2107  C C   . PRO A 1 269 ? -36.142 -20.123 13.243  1.00 47.71  ? 269 PRO A C   1 
ATOM   2108  O O   . PRO A 1 269 ? -37.206 -19.537 13.097  1.00 49.37  ? 269 PRO A O   1 
ATOM   2109  C CB  . PRO A 1 269 ? -34.075 -18.715 13.316  1.00 54.17  ? 269 PRO A CB  1 
ATOM   2110  C CG  . PRO A 1 269 ? -32.707 -18.996 13.913  1.00 57.85  ? 269 PRO A CG  1 
ATOM   2111  C CD  . PRO A 1 269 ? -32.778 -20.402 14.466  1.00 52.39  ? 269 PRO A CD  1 
ATOM   2112  N N   . LEU A 1 270 ? -35.853 -21.265 12.612  1.00 49.51  ? 270 LEU A N   1 
ATOM   2113  C CA  . LEU A 1 270 ? -36.802 -21.915 11.719  1.00 48.92  ? 270 LEU A CA  1 
ATOM   2114  C C   . LEU A 1 270 ? -37.804 -22.765 12.507  1.00 51.37  ? 270 LEU A C   1 
ATOM   2115  O O   . LEU A 1 270 ? -38.606 -23.472 11.913  1.00 53.57  ? 270 LEU A O   1 
ATOM   2116  C CB  . LEU A 1 270 ? -36.048 -22.818 10.736  1.00 45.03  ? 270 LEU A CB  1 
ATOM   2117  C CG  . LEU A 1 270 ? -35.047 -22.122 9.822   1.00 44.26  ? 270 LEU A CG  1 
ATOM   2118  C CD1 . LEU A 1 270 ? -34.539 -23.091 8.754   1.00 38.98  ? 270 LEU A CD1 1 
ATOM   2119  C CD2 . LEU A 1 270 ? -35.673 -20.869 9.202   1.00 40.23  ? 270 LEU A CD2 1 
ATOM   2120  N N   . HIS A 1 271 ? -37.759 -22.736 13.838  1.00 53.81  ? 271 HIS A N   1 
ATOM   2121  C CA  . HIS A 1 271 ? -38.723 -23.473 14.628  1.00 55.24  ? 271 HIS A CA  1 
ATOM   2122  C C   . HIS A 1 271 ? -39.428 -22.556 15.641  1.00 55.95  ? 271 HIS A C   1 
ATOM   2123  O O   . HIS A 1 271 ? -40.624 -22.290 15.525  1.00 58.59  ? 271 HIS A O   1 
ATOM   2124  C CB  . HIS A 1 271 ? -38.007 -24.675 15.253  1.00 54.24  ? 271 HIS A CB  1 
ATOM   2125  C CG  . HIS A 1 271 ? -38.942 -25.740 15.723  1.00 59.13  ? 271 HIS A CG  1 
ATOM   2126  N ND1 . HIS A 1 271 ? -40.300 -25.710 15.510  1.00 66.93  ? 271 HIS A ND1 1 
ATOM   2127  C CD2 . HIS A 1 271 ? -38.682 -26.872 16.416  1.00 66.53  ? 271 HIS A CD2 1 
ATOM   2128  C CE1 . HIS A 1 271 ? -40.856 -26.788 16.046  1.00 60.00  ? 271 HIS A CE1 1 
ATOM   2129  N NE2 . HIS A 1 271 ? -39.869 -27.525 16.616  1.00 72.42  ? 271 HIS A NE2 1 
ATOM   2130  N N   . GLY A 1 272 ? -38.678 -22.029 16.614  1.00 55.84  ? 272 GLY A N   1 
ATOM   2131  C CA  . GLY A 1 272 ? -39.283 -21.431 17.789  1.00 57.93  ? 272 GLY A CA  1 
ATOM   2132  C C   . GLY A 1 272 ? -39.365 -19.906 17.753  1.00 63.75  ? 272 GLY A C   1 
ATOM   2133  O O   . GLY A 1 272 ? -39.980 -19.326 18.653  1.00 58.21  ? 272 GLY A O   1 
ATOM   2134  N N   . LEU A 1 273 ? -38.769 -19.264 16.738  1.00 62.65  ? 273 LEU A N   1 
ATOM   2135  C CA  . LEU A 1 273 ? -38.631 -17.808 16.748  1.00 68.78  ? 273 LEU A CA  1 
ATOM   2136  C C   . LEU A 1 273 ? -39.630 -17.142 15.802  1.00 70.57  ? 273 LEU A C   1 
ATOM   2137  O O   . LEU A 1 273 ? -39.612 -15.923 15.675  1.00 66.78  ? 273 LEU A O   1 
ATOM   2138  C CB  . LEU A 1 273 ? -37.195 -17.430 16.366  1.00 74.74  ? 273 LEU A CB  1 
ATOM   2139  C CG  . LEU A 1 273 ? -36.206 -17.243 17.525  1.00 78.44  ? 273 LEU A CG  1 
ATOM   2140  C CD1 . LEU A 1 273 ? -36.224 -18.431 18.495  1.00 74.25  ? 273 LEU A CD1 1 
ATOM   2141  C CD2 . LEU A 1 273 ? -34.788 -16.992 16.979  1.00 72.28  ? 273 LEU A CD2 1 
ATOM   2142  N N   . ALA A 1 274 ? -40.512 -17.936 15.173  1.00 64.91  ? 274 ALA A N   1 
ATOM   2143  C CA  . ALA A 1 274 ? -41.459 -17.429 14.190  1.00 67.29  ? 274 ALA A CA  1 
ATOM   2144  C C   . ALA A 1 274 ? -42.469 -16.447 14.811  1.00 67.13  ? 274 ALA A C   1 
ATOM   2145  O O   . ALA A 1 274 ? -42.937 -15.536 14.139  1.00 47.80  ? 274 ALA A O   1 
ATOM   2146  C CB  . ALA A 1 274 ? -42.147 -18.611 13.538  1.00 68.40  ? 274 ALA A CB  1 
ATOM   2147  N N   . ASN A 1 275 ? -42.773 -16.614 16.109  1.00 76.35  ? 275 ASN A N   1 
ATOM   2148  C CA  . ASN A 1 275 ? -43.826 -15.887 16.809  1.00 76.82  ? 275 ASN A CA  1 
ATOM   2149  C C   . ASN A 1 275 ? -43.445 -14.415 17.047  1.00 80.38  ? 275 ASN A C   1 
ATOM   2150  O O   . ASN A 1 275 ? -44.279 -13.524 16.834  1.00 72.06  ? 275 ASN A O   1 
ATOM   2151  C CB  . ASN A 1 275 ? -44.170 -16.646 18.099  1.00 84.63  ? 275 ASN A CB  1 
ATOM   2152  C CG  . ASN A 1 275 ? -45.321 -16.059 18.890  1.00 91.85  ? 275 ASN A CG  1 
ATOM   2153  O OD1 . ASN A 1 275 ? -45.832 -14.990 18.558  1.00 116.91 ? 275 ASN A OD1 1 
ATOM   2154  N ND2 . ASN A 1 275 ? -45.737 -16.756 19.936  1.00 84.65  ? 275 ASN A ND2 1 
ATOM   2155  N N   . GLN A 1 276 ? -42.204 -14.178 17.520  1.00 81.73  ? 276 GLN A N   1 
ATOM   2156  C CA  . GLN A 1 276 ? -41.662 -12.837 17.735  1.00 79.88  ? 276 GLN A CA  1 
ATOM   2157  C C   . GLN A 1 276 ? -41.369 -12.159 16.396  1.00 88.02  ? 276 GLN A C   1 
ATOM   2158  O O   . GLN A 1 276 ? -41.631 -10.960 16.254  1.00 76.08  ? 276 GLN A O   1 
ATOM   2159  C CB  . GLN A 1 276 ? -40.389 -12.787 18.599  1.00 76.84  ? 276 GLN A CB  1 
ATOM   2160  C CG  . GLN A 1 276 ? -39.388 -13.914 18.388  1.00 82.39  ? 276 GLN A CG  1 
ATOM   2161  C CD  . GLN A 1 276 ? -39.681 -15.089 19.306  1.00 91.66  ? 276 GLN A CD  1 
ATOM   2162  O OE1 . GLN A 1 276 ? -40.760 -15.691 19.268  1.00 71.69  ? 276 GLN A OE1 1 
ATOM   2163  N NE2 . GLN A 1 276 ? -38.725 -15.419 20.165  1.00 77.94  ? 276 GLN A NE2 1 
ATOM   2164  N N   . GLU A 1 277 ? -40.827 -12.924 15.432  1.00 90.19  ? 277 GLU A N   1 
ATOM   2165  C CA  . GLU A 1 277 ? -40.458 -12.395 14.123  1.00 85.57  ? 277 GLU A CA  1 
ATOM   2166  C C   . GLU A 1 277 ? -41.700 -11.935 13.356  1.00 75.30  ? 277 GLU A C   1 
ATOM   2167  O O   . GLU A 1 277 ? -41.593 -11.070 12.497  1.00 80.20  ? 277 GLU A O   1 
ATOM   2168  C CB  . GLU A 1 277 ? -39.602 -13.407 13.356  1.00 88.36  ? 277 GLU A CB  1 
ATOM   2169  C CG  . GLU A 1 277 ? -38.204 -13.572 13.963  1.00 101.09 ? 277 GLU A CG  1 
ATOM   2170  C CD  . GLU A 1 277 ? -37.262 -14.548 13.264  1.00 106.25 ? 277 GLU A CD  1 
ATOM   2171  O OE1 . GLU A 1 277 ? -37.599 -14.995 12.158  1.00 115.39 ? 277 GLU A OE1 1 
ATOM   2172  O OE2 . GLU A 1 277 ? -36.202 -14.890 13.840  1.00 103.10 ? 277 GLU A OE2 1 
ATOM   2173  N N   . VAL A 1 278 ? -42.882 -12.451 13.713  1.00 70.09  ? 278 VAL A N   1 
ATOM   2174  C CA  . VAL A 1 278 ? -44.145 -11.974 13.163  1.00 67.66  ? 278 VAL A CA  1 
ATOM   2175  C C   . VAL A 1 278 ? -44.518 -10.619 13.758  1.00 65.58  ? 278 VAL A C   1 
ATOM   2176  O O   . VAL A 1 278 ? -44.831 -9.689  13.020  1.00 66.21  ? 278 VAL A O   1 
ATOM   2177  C CB  . VAL A 1 278 ? -45.296 -12.971 13.401  1.00 64.20  ? 278 VAL A CB  1 
ATOM   2178  C CG1 . VAL A 1 278 ? -46.665 -12.312 13.268  1.00 53.71  ? 278 VAL A CG1 1 
ATOM   2179  C CG2 . VAL A 1 278 ? -45.176 -14.164 12.477  1.00 60.55  ? 278 VAL A CG2 1 
ATOM   2180  N N   . LEU A 1 279 ? -44.574 -10.558 15.089  1.00 61.65  ? 279 LEU A N   1 
ATOM   2181  C CA  . LEU A 1 279 ? -45.064 -9.390  15.807  1.00 65.17  ? 279 LEU A CA  1 
ATOM   2182  C C   . LEU A 1 279 ? -44.175 -8.180  15.516  1.00 68.37  ? 279 LEU A C   1 
ATOM   2183  O O   . LEU A 1 279 ? -44.696 -7.107  15.195  1.00 55.87  ? 279 LEU A O   1 
ATOM   2184  C CB  . LEU A 1 279 ? -45.106 -9.710  17.309  1.00 63.17  ? 279 LEU A CB  1 
ATOM   2185  C CG  . LEU A 1 279 ? -45.619 -8.595  18.215  1.00 63.80  ? 279 LEU A CG  1 
ATOM   2186  C CD1 . LEU A 1 279 ? -47.047 -8.207  17.858  1.00 64.47  ? 279 LEU A CD1 1 
ATOM   2187  C CD2 . LEU A 1 279 ? -45.555 -9.021  19.668  1.00 63.92  ? 279 LEU A CD2 1 
ATOM   2188  N N   . LYS A 1 280 ? -42.843 -8.370  15.630  1.00 76.21  ? 280 LYS A N   1 
ATOM   2189  C CA  . LYS A 1 280 ? -41.852 -7.328  15.349  1.00 74.98  ? 280 LYS A CA  1 
ATOM   2190  C C   . LYS A 1 280 ? -42.124 -6.698  13.985  1.00 71.09  ? 280 LYS A C   1 
ATOM   2191  O O   . LYS A 1 280 ? -42.107 -5.481  13.831  1.00 57.66  ? 280 LYS A O   1 
ATOM   2192  C CB  . LYS A 1 280 ? -40.424 -7.887  15.343  1.00 65.84  ? 280 LYS A CB  1 
ATOM   2193  C CG  . LYS A 1 280 ? -39.832 -8.073  16.727  1.00 64.73  ? 280 LYS A CG  1 
ATOM   2194  C CD  . LYS A 1 280 ? -38.441 -8.666  16.788  1.00 69.58  ? 280 LYS A CD  1 
ATOM   2195  C CE  . LYS A 1 280 ? -37.672 -8.172  18.005  1.00 72.48  ? 280 LYS A CE  1 
ATOM   2196  N NZ  . LYS A 1 280 ? -36.960 -9.254  18.719  1.00 76.14  ? 280 LYS A NZ  1 
ATOM   2197  N N   . TRP A 1 281 ? -42.359 -7.569  13.008  1.00 71.04  ? 281 TRP A N   1 
ATOM   2198  C CA  . TRP A 1 281 ? -42.610 -7.173  11.639  1.00 77.89  ? 281 TRP A CA  1 
ATOM   2199  C C   . TRP A 1 281 ? -43.960 -6.448  11.511  1.00 82.88  ? 281 TRP A C   1 
ATOM   2200  O O   . TRP A 1 281 ? -44.075 -5.514  10.715  1.00 82.99  ? 281 TRP A O   1 
ATOM   2201  C CB  . TRP A 1 281 ? -42.451 -8.418  10.752  1.00 82.09  ? 281 TRP A CB  1 
ATOM   2202  C CG  . TRP A 1 281 ? -42.805 -8.226  9.314   1.00 83.90  ? 281 TRP A CG  1 
ATOM   2203  C CD1 . TRP A 1 281 ? -41.952 -8.009  8.272   1.00 79.66  ? 281 TRP A CD1 1 
ATOM   2204  C CD2 . TRP A 1 281 ? -44.130 -8.286  8.759   1.00 85.86  ? 281 TRP A CD2 1 
ATOM   2205  N NE1 . TRP A 1 281 ? -42.664 -7.892  7.108   1.00 79.72  ? 281 TRP A NE1 1 
ATOM   2206  C CE2 . TRP A 1 281 ? -44.001 -8.055  7.374   1.00 83.47  ? 281 TRP A CE2 1 
ATOM   2207  C CE3 . TRP A 1 281 ? -45.408 -8.500  9.298   1.00 87.06  ? 281 TRP A CE3 1 
ATOM   2208  C CZ2 . TRP A 1 281 ? -45.107 -8.052  6.520   1.00 90.90  ? 281 TRP A CZ2 1 
ATOM   2209  C CZ3 . TRP A 1 281 ? -46.500 -8.483  8.453   1.00 92.14  ? 281 TRP A CZ3 1 
ATOM   2210  C CH2 . TRP A 1 281 ? -46.351 -8.258  7.082   1.00 87.34  ? 281 TRP A CH2 1 
ATOM   2211  N N   . ILE A 1 282 ? -44.975 -6.817  12.310  1.00 89.02  ? 282 ILE A N   1 
ATOM   2212  C CA  . ILE A 1 282 ? -46.243 -6.090  12.310  1.00 84.43  ? 282 ILE A CA  1 
ATOM   2213  C C   . ILE A 1 282 ? -46.029 -4.712  12.930  1.00 81.47  ? 282 ILE A C   1 
ATOM   2214  O O   . ILE A 1 282 ? -46.550 -3.731  12.419  1.00 95.99  ? 282 ILE A O   1 
ATOM   2215  C CB  . ILE A 1 282 ? -47.376 -6.862  13.023  1.00 90.43  ? 282 ILE A CB  1 
ATOM   2216  C CG1 . ILE A 1 282 ? -47.812 -8.095  12.227  1.00 95.22  ? 282 ILE A CG1 1 
ATOM   2217  C CG2 . ILE A 1 282 ? -48.567 -5.958  13.305  1.00 89.95  ? 282 ILE A CG2 1 
ATOM   2218  C CD1 . ILE A 1 282 ? -48.963 -8.850  12.858  1.00 93.78  ? 282 ILE A CD1 1 
ATOM   2219  N N   . GLN A 1 283 ? -45.259 -4.648  14.020  1.00 83.96  ? 283 GLN A N   1 
ATOM   2220  C CA  . GLN A 1 283 ? -44.998 -3.406  14.740  1.00 84.91  ? 283 GLN A CA  1 
ATOM   2221  C C   . GLN A 1 283 ? -44.124 -2.443  13.927  1.00 84.45  ? 283 GLN A C   1 
ATOM   2222  O O   . GLN A 1 283 ? -44.319 -1.235  14.002  1.00 76.41  ? 283 GLN A O   1 
ATOM   2223  C CB  . GLN A 1 283 ? -44.330 -3.722  16.082  1.00 85.03  ? 283 GLN A CB  1 
ATOM   2224  C CG  . GLN A 1 283 ? -45.256 -4.426  17.064  1.00 79.31  ? 283 GLN A CG  1 
ATOM   2225  C CD  . GLN A 1 283 ? -44.574 -4.692  18.381  1.00 74.34  ? 283 GLN A CD  1 
ATOM   2226  O OE1 . GLN A 1 283 ? -45.081 -4.333  19.437  1.00 76.56  ? 283 GLN A OE1 1 
ATOM   2227  N NE2 . GLN A 1 283 ? -43.417 -5.332  18.325  1.00 69.96  ? 283 GLN A NE2 1 
ATOM   2228  N N   . GLU A 1 284 ? -43.131 -2.985  13.205  1.00 95.18  ? 284 GLU A N   1 
ATOM   2229  C CA  . GLU A 1 284 ? -42.279 -2.235  12.286  1.00 97.02  ? 284 GLU A CA  1 
ATOM   2230  C C   . GLU A 1 284 ? -43.121 -1.635  11.157  1.00 92.59  ? 284 GLU A C   1 
ATOM   2231  O O   . GLU A 1 284 ? -42.842 -0.532  10.696  1.00 93.16  ? 284 GLU A O   1 
ATOM   2232  C CB  . GLU A 1 284 ? -41.187 -3.166  11.742  1.00 103.27 ? 284 GLU A CB  1 
ATOM   2233  C CG  . GLU A 1 284 ? -40.466 -2.661  10.501  1.00 112.45 ? 284 GLU A CG  1 
ATOM   2234  C CD  . GLU A 1 284 ? -40.409 -3.663  9.355   1.00 121.41 ? 284 GLU A CD  1 
ATOM   2235  O OE1 . GLU A 1 284 ? -39.895 -4.789  9.559   1.00 126.81 ? 284 GLU A OE1 1 
ATOM   2236  O OE2 . GLU A 1 284 ? -40.915 -3.323  8.267   1.00 117.16 ? 284 GLU A OE2 1 
ATOM   2237  N N   . THR A 1 285 ? -44.147 -2.376  10.711  1.00 93.44  ? 285 THR A N   1 
ATOM   2238  C CA  . THR A 1 285 ? -44.990 -2.007  9.579   1.00 93.91  ? 285 THR A CA  1 
ATOM   2239  C C   . THR A 1 285 ? -46.019 -0.928  9.953   1.00 92.14  ? 285 THR A C   1 
ATOM   2240  O O   . THR A 1 285 ? -46.172 0.040   9.213   1.00 85.08  ? 285 THR A O   1 
ATOM   2241  C CB  . THR A 1 285 ? -45.639 -3.269  8.992   1.00 99.22  ? 285 THR A CB  1 
ATOM   2242  O OG1 . THR A 1 285 ? -44.637 -3.972  8.249   1.00 94.64  ? 285 THR A OG1 1 
ATOM   2243  C CG2 . THR A 1 285 ? -46.827 -2.980  8.102   1.00 95.19  ? 285 THR A CG2 1 
ATOM   2244  N N   . ILE A 1 286 ? -46.741 -1.105  11.075  1.00 91.52  ? 286 ILE A N   1 
ATOM   2245  C CA  . ILE A 1 286 ? -47.634 -0.092  11.629  1.00 83.93  ? 286 ILE A CA  1 
ATOM   2246  C C   . ILE A 1 286 ? -46.891 1.224   11.840  1.00 88.87  ? 286 ILE A C   1 
ATOM   2247  O O   . ILE A 1 286 ? -47.501 2.275   11.737  1.00 108.09 ? 286 ILE A O   1 
ATOM   2248  C CB  . ILE A 1 286 ? -48.238 -0.546  12.977  1.00 91.06  ? 286 ILE A CB  1 
ATOM   2249  C CG1 . ILE A 1 286 ? -49.209 -1.724  12.827  1.00 96.96  ? 286 ILE A CG1 1 
ATOM   2250  C CG2 . ILE A 1 286 ? -48.884 0.618   13.726  1.00 84.49  ? 286 ILE A CG2 1 
ATOM   2251  C CD1 . ILE A 1 286 ? -49.665 -2.323  14.155  1.00 90.34  ? 286 ILE A CD1 1 
ATOM   2252  N N   . ASP A 1 287 ? -45.609 1.163   12.218  1.00 92.44  ? 287 ASP A N   1 
ATOM   2253  C CA  . ASP A 1 287 ? -44.816 2.339   12.550  1.00 96.39  ? 287 ASP A CA  1 
ATOM   2254  C C   . ASP A 1 287 ? -44.319 3.048   11.286  1.00 99.77  ? 287 ASP A C   1 
ATOM   2255  O O   . ASP A 1 287 ? -44.485 4.261   11.161  1.00 94.15  ? 287 ASP A O   1 
ATOM   2256  C CB  . ASP A 1 287 ? -43.630 1.959   13.437  1.00 98.36  ? 287 ASP A CB  1 
ATOM   2257  C CG  . ASP A 1 287 ? -42.806 3.157   13.869  1.00 105.82 ? 287 ASP A CG  1 
ATOM   2258  O OD1 . ASP A 1 287 ? -43.326 3.955   14.682  1.00 111.90 ? 287 ASP A OD1 1 
ATOM   2259  O OD2 . ASP A 1 287 ? -41.663 3.294   13.370  1.00 102.49 ? 287 ASP A OD2 1 
ATOM   2260  N N   . LYS A 1 288 ? -43.826 2.280   10.321  1.00 101.86 ? 288 LYS A N   1 
ATOM   2261  C CA  . LYS A 1 288 ? -43.207 2.924   9.139   1.00 101.01 ? 288 LYS A CA  1 
ATOM   2262  C C   . LYS A 1 288 ? -44.184 3.168   7.998   1.00 112.21 ? 288 LYS A C   1 
ATOM   2263  O O   . LYS A 1 288 ? -44.497 4.342   7.742   1.00 114.15 ? 288 LYS A O   1 
ATOM   2264  C CB  . LYS A 1 288 ? -42.122 2.012   8.572   1.00 103.79 ? 288 LYS A CB  1 
ATOM   2265  C CG  . LYS A 1 288 ? -40.691 2.430   8.875   1.00 107.51 ? 288 LYS A CG  1 
ATOM   2266  C CD  . LYS A 1 288 ? -40.174 1.877   10.181  1.00 100.91 ? 288 LYS A CD  1 
ATOM   2267  C CE  . LYS A 1 288 ? -39.291 2.860   10.918  1.00 99.55  ? 288 LYS A CE  1 
ATOM   2268  N NZ  . LYS A 1 288 ? -39.253 2.576   12.371  1.00 104.70 ? 288 LYS A NZ  1 
ATOM   2269  N N   . LYS A 1 289 ? -44.701 2.109   7.382   1.00 125.69 ? 289 LYS A N   1 
ATOM   2270  C CA  . LYS A 1 289 ? -45.452 2.267   6.142   1.00 133.82 ? 289 LYS A CA  1 
ATOM   2271  C C   . LYS A 1 289 ? -46.828 2.909   6.349   1.00 136.50 ? 289 LYS A C   1 
ATOM   2272  O O   . LYS A 1 289 ? -47.347 3.522   5.418   1.00 145.95 ? 289 LYS A O   1 
ATOM   2273  C CB  . LYS A 1 289 ? -45.607 0.905   5.450   1.00 134.92 ? 289 LYS A CB  1 
ATOM   2274  C CG  . LYS A 1 289 ? -44.540 0.572   4.415   1.00 137.79 ? 289 LYS A CG  1 
ATOM   2275  C CD  . LYS A 1 289 ? -43.136 0.439   4.944   1.00 134.62 ? 289 LYS A CD  1 
ATOM   2276  C CE  . LYS A 1 289 ? -42.175 0.078   3.833   1.00 129.85 ? 289 LYS A CE  1 
ATOM   2277  N NZ  . LYS A 1 289 ? -40.778 0.235   4.282   1.00 130.12 ? 289 LYS A NZ  1 
ATOM   2278  N N   . LEU A 1 290 ? -47.426 2.750   7.541   1.00 129.44 ? 290 LEU A N   1 
ATOM   2279  C CA  . LEU A 1 290 ? -48.823 3.104   7.771   1.00 111.16 ? 290 LEU A CA  1 
ATOM   2280  C C   . LEU A 1 290 ? -48.952 4.081   8.936   1.00 96.74  ? 290 LEU A C   1 
ATOM   2281  O O   . LEU A 1 290 ? -50.056 4.230   9.454   1.00 92.43  ? 290 LEU A O   1 
ATOM   2282  C CB  . LEU A 1 290 ? -49.617 1.824   8.059   1.00 113.36 ? 290 LEU A CB  1 
ATOM   2283  C CG  . LEU A 1 290 ? -49.161 0.583   7.286   1.00 118.54 ? 290 LEU A CG  1 
ATOM   2284  C CD1 . LEU A 1 290 ? -49.721 -0.677  7.918   1.00 121.44 ? 290 LEU A CD1 1 
ATOM   2285  C CD2 . LEU A 1 290 ? -49.535 0.666   5.808   1.00 113.55 ? 290 LEU A CD2 1 
ATOM   2286  N N   . GLY A 1 291 ? -47.822 4.670   9.367   1.00 96.05  ? 291 GLY A N   1 
ATOM   2287  C CA  . GLY A 1 291 ? -47.777 5.892   10.166  1.00 115.76 ? 291 GLY A CA  1 
ATOM   2288  C C   . GLY A 1 291 ? -48.306 5.769   11.602  1.00 127.83 ? 291 GLY A C   1 
ATOM   2289  O O   . GLY A 1 291 ? -49.022 6.658   12.069  1.00 131.77 ? 291 GLY A O   1 
ATOM   2290  N N   . GLY A 1 292 ? -47.927 4.697   12.314  1.00 125.05 ? 292 GLY A N   1 
ATOM   2291  C CA  . GLY A 1 292 ? -48.301 4.496   13.710  1.00 116.09 ? 292 GLY A CA  1 
ATOM   2292  C C   . GLY A 1 292 ? -49.814 4.402   13.935  1.00 116.55 ? 292 GLY A C   1 
ATOM   2293  O O   . GLY A 1 292 ? -50.298 4.728   15.019  1.00 97.61  ? 292 GLY A O   1 
ATOM   2294  N N   . LYS A 1 293 ? -50.552 3.943   12.913  1.00 120.46 ? 293 LYS A N   1 
ATOM   2295  C CA  . LYS A 1 293 ? -52.006 3.864   12.963  1.00 126.91 ? 293 LYS A CA  1 
ATOM   2296  C C   . LYS A 1 293 ? -52.443 2.638   12.155  1.00 127.06 ? 293 LYS A C   1 
ATOM   2297  O O   . LYS A 1 293 ? -51.768 2.252   11.192  1.00 121.92 ? 293 LYS A O   1 
ATOM   2298  C CB  . LYS A 1 293 ? -52.588 5.232   12.556  1.00 120.74 ? 293 LYS A CB  1 
ATOM   2299  C CG  . LYS A 1 293 ? -53.935 5.305   11.831  1.00 123.41 ? 293 LYS A CG  1 
ATOM   2300  C CD  . LYS A 1 293 ? -55.127 4.490   12.354  1.00 123.50 ? 293 LYS A CD  1 
ATOM   2301  C CE  . LYS A 1 293 ? -55.252 4.348   13.856  1.00 125.89 ? 293 LYS A CE  1 
ATOM   2302  N NZ  . LYS A 1 293 ? -55.513 5.641   14.520  1.00 138.32 ? 293 LYS A NZ  1 
ATOM   2303  N N   . VAL A 1 294 ? -53.522 1.990   12.637  1.00 118.76 ? 294 VAL A N   1 
ATOM   2304  C CA  . VAL A 1 294 ? -54.218 0.908   11.951  1.00 113.38 ? 294 VAL A CA  1 
ATOM   2305  C C   . VAL A 1 294 ? -54.521 1.342   10.518  1.00 113.21 ? 294 VAL A C   1 
ATOM   2306  O O   . VAL A 1 294 ? -55.324 2.250   10.310  1.00 113.29 ? 294 VAL A O   1 
ATOM   2307  C CB  . VAL A 1 294 ? -55.536 0.510   12.655  1.00 108.08 ? 294 VAL A CB  1 
ATOM   2308  C CG1 . VAL A 1 294 ? -56.108 -0.782  12.083  1.00 97.50  ? 294 VAL A CG1 1 
ATOM   2309  C CG2 . VAL A 1 294 ? -55.395 0.420   14.168  1.00 107.93 ? 294 VAL A CG2 1 
ATOM   2310  N N   . PRO A 1 295 ? -53.945 0.692   9.482   1.00 112.22 ? 295 PRO A N   1 
ATOM   2311  C CA  . PRO A 1 295 ? -54.240 1.076   8.104   1.00 117.07 ? 295 PRO A CA  1 
ATOM   2312  C C   . PRO A 1 295 ? -55.698 0.790   7.750   1.00 132.63 ? 295 PRO A C   1 
ATOM   2313  O O   . PRO A 1 295 ? -56.397 0.085   8.482   1.00 140.08 ? 295 PRO A O   1 
ATOM   2314  C CB  . PRO A 1 295 ? -53.294 0.194   7.284   1.00 112.76 ? 295 PRO A CB  1 
ATOM   2315  C CG  . PRO A 1 295 ? -53.098 -1.023  8.157   1.00 111.89 ? 295 PRO A CG  1 
ATOM   2316  C CD  . PRO A 1 295 ? -53.052 -0.474  9.566   1.00 106.96 ? 295 PRO A CD  1 
ATOM   2317  N N   . THR A 1 296 ? -56.152 1.384   6.640   1.00 150.73 ? 296 THR A N   1 
ATOM   2318  C CA  . THR A 1 296 ? -57.350 0.925   5.960   1.00 145.85 ? 296 THR A CA  1 
ATOM   2319  C C   . THR A 1 296 ? -56.989 -0.358  5.208   1.00 150.15 ? 296 THR A C   1 
ATOM   2320  O O   . THR A 1 296 ? -55.812 -0.652  4.979   1.00 155.07 ? 296 THR A O   1 
ATOM   2321  C CB  . THR A 1 296 ? -57.935 2.019   5.050   1.00 127.23 ? 296 THR A CB  1 
ATOM   2322  O OG1 . THR A 1 296 ? -56.904 2.375   4.126   1.00 105.63 ? 296 THR A OG1 1 
ATOM   2323  C CG2 . THR A 1 296 ? -58.437 3.235   5.805   1.00 111.36 ? 296 THR A CG2 1 
ATOM   2324  N N   . LYS A 1 297 ? -58.018 -1.110  4.811   1.00 138.52 ? 297 LYS A N   1 
ATOM   2325  C CA  . LYS A 1 297 ? -57.835 -2.439  4.246   1.00 125.28 ? 297 LYS A CA  1 
ATOM   2326  C C   . LYS A 1 297 ? -56.923 -2.375  3.013   1.00 116.40 ? 297 LYS A C   1 
ATOM   2327  O O   . LYS A 1 297 ? -56.318 -3.373  2.617   1.00 92.98  ? 297 LYS A O   1 
ATOM   2328  C CB  . LYS A 1 297 ? -59.215 -3.043  3.964   1.00 126.34 ? 297 LYS A CB  1 
ATOM   2329  C CG  . LYS A 1 297 ? -59.256 -4.557  4.058   1.00 125.82 ? 297 LYS A CG  1 
ATOM   2330  C CD  . LYS A 1 297 ? -60.594 -5.134  3.667   1.00 121.09 ? 297 LYS A CD  1 
ATOM   2331  C CE  . LYS A 1 297 ? -60.537 -6.640  3.499   1.00 119.54 ? 297 LYS A CE  1 
ATOM   2332  N NZ  . LYS A 1 297 ? -61.556 -7.142  2.543   1.00 116.15 ? 297 LYS A NZ  1 
ATOM   2333  N N   . GLU A 1 298 ? -56.768 -1.165  2.455   1.00 127.76 ? 298 GLU A N   1 
ATOM   2334  C CA  . GLU A 1 298 ? -56.306 -0.966  1.090   1.00 126.21 ? 298 GLU A CA  1 
ATOM   2335  C C   . GLU A 1 298 ? -54.802 -0.691  1.049   1.00 119.46 ? 298 GLU A C   1 
ATOM   2336  O O   . GLU A 1 298 ? -54.118 -1.184  0.156   1.00 107.70 ? 298 GLU A O   1 
ATOM   2337  C CB  . GLU A 1 298 ? -57.107 0.178   0.461   1.00 129.26 ? 298 GLU A CB  1 
ATOM   2338  C CG  . GLU A 1 298 ? -57.679 -0.160  -0.901  1.00 131.91 ? 298 GLU A CG  1 
ATOM   2339  C CD  . GLU A 1 298 ? -58.544 -1.417  -0.926  1.00 141.45 ? 298 GLU A CD  1 
ATOM   2340  O OE1 . GLU A 1 298 ? -59.576 -1.450  -0.224  1.00 140.27 ? 298 GLU A OE1 1 
ATOM   2341  O OE2 . GLU A 1 298 ? -58.175 -2.378  -1.631  1.00 158.92 ? 298 GLU A OE2 1 
ATOM   2342  N N   . GLU A 1 299 ? -54.303 0.119   1.994   1.00 124.16 ? 299 GLU A N   1 
ATOM   2343  C CA  . GLU A 1 299 ? -52.884 0.432   2.102   1.00 124.19 ? 299 GLU A CA  1 
ATOM   2344  C C   . GLU A 1 299 ? -52.106 -0.799  2.547   1.00 129.69 ? 299 GLU A C   1 
ATOM   2345  O O   . GLU A 1 299 ? -50.927 -0.939  2.226   1.00 137.02 ? 299 GLU A O   1 
ATOM   2346  C CB  . GLU A 1 299 ? -52.649 1.543   3.123   1.00 124.00 ? 299 GLU A CB  1 
ATOM   2347  C CG  . GLU A 1 299 ? -53.227 2.877   2.693   1.00 136.54 ? 299 GLU A CG  1 
ATOM   2348  C CD  . GLU A 1 299 ? -53.598 3.813   3.829   1.00 140.32 ? 299 GLU A CD  1 
ATOM   2349  O OE1 . GLU A 1 299 ? -53.529 3.382   5.009   1.00 141.24 ? 299 GLU A OE1 1 
ATOM   2350  O OE2 . GLU A 1 299 ? -53.966 4.966   3.527   1.00 136.03 ? 299 GLU A OE2 1 
ATOM   2351  N N   . LEU A 1 300 ? -52.776 -1.661  3.321   1.00 123.92 ? 300 LEU A N   1 
ATOM   2352  C CA  . LEU A 1 300 ? -52.215 -2.947  3.694   1.00 114.88 ? 300 LEU A CA  1 
ATOM   2353  C C   . LEU A 1 300 ? -52.207 -3.872  2.477   1.00 104.36 ? 300 LEU A C   1 
ATOM   2354  O O   . LEU A 1 300 ? -51.178 -4.491  2.203   1.00 73.40  ? 300 LEU A O   1 
ATOM   2355  C CB  . LEU A 1 300 ? -53.038 -3.537  4.846   1.00 121.93 ? 300 LEU A CB  1 
ATOM   2356  C CG  . LEU A 1 300 ? -52.431 -4.772  5.509   1.00 121.44 ? 300 LEU A CG  1 
ATOM   2357  C CD1 . LEU A 1 300 ? -51.122 -4.409  6.194   1.00 123.89 ? 300 LEU A CD1 1 
ATOM   2358  C CD2 . LEU A 1 300 ? -53.405 -5.414  6.494   1.00 122.39 ? 300 LEU A CD2 1 
ATOM   2359  N N   . LYS A 1 301 ? -53.346 -3.926  1.754   1.00 104.92 ? 301 LYS A N   1 
ATOM   2360  C CA  . LYS A 1 301 ? -53.540 -4.828  0.621   1.00 102.42 ? 301 LYS A CA  1 
ATOM   2361  C C   . LYS A 1 301 ? -52.392 -4.680  -0.379  1.00 105.95 ? 301 LYS A C   1 
ATOM   2362  O O   . LYS A 1 301 ? -51.888 -5.680  -0.886  1.00 108.63 ? 301 LYS A O   1 
ATOM   2363  C CB  . LYS A 1 301 ? -54.903 -4.609  -0.055  1.00 81.65  ? 301 LYS A CB  1 
ATOM   2364  N N   . LYS A 1 302 ? -51.958 -3.440  -0.646  1.00 127.67 ? 302 LYS A N   1 
ATOM   2365  C CA  . LYS A 1 302 ? -50.911 -3.202  -1.631  1.00 135.83 ? 302 LYS A CA  1 
ATOM   2366  C C   . LYS A 1 302 ? -49.527 -3.140  -0.971  1.00 141.45 ? 302 LYS A C   1 
ATOM   2367  O O   . LYS A 1 302 ? -48.503 -3.181  -1.667  1.00 144.77 ? 302 LYS A O   1 
ATOM   2368  C CB  . LYS A 1 302 ? -51.226 -1.952  -2.461  1.00 130.73 ? 302 LYS A CB  1 
ATOM   2369  C CG  . LYS A 1 302 ? -51.269 -0.636  -1.697  1.00 125.25 ? 302 LYS A CG  1 
ATOM   2370  C CD  . LYS A 1 302 ? -50.737 0.533   -2.502  1.00 117.85 ? 302 LYS A CD  1 
ATOM   2371  C CE  . LYS A 1 302 ? -49.257 0.404   -2.795  1.00 112.02 ? 302 LYS A CE  1 
ATOM   2372  N NZ  . LYS A 1 302 ? -48.658 1.722   -3.099  1.00 107.09 ? 302 LYS A NZ  1 
ATOM   2373  N N   . PHE A 1 303 ? -49.484 -3.067  0.370   1.00 135.84 ? 303 PHE A N   1 
ATOM   2374  C CA  . PHE A 1 303 ? -48.220 -3.127  1.091   1.00 124.12 ? 303 PHE A CA  1 
ATOM   2375  C C   . PHE A 1 303 ? -47.629 -4.537  1.047   1.00 121.34 ? 303 PHE A C   1 
ATOM   2376  O O   . PHE A 1 303 ? -46.408 -4.700  1.045   1.00 115.92 ? 303 PHE A O   1 
ATOM   2377  C CB  . PHE A 1 303 ? -48.363 -2.708  2.555   1.00 122.08 ? 303 PHE A CB  1 
ATOM   2378  C CG  . PHE A 1 303 ? -47.141 -3.079  3.349   1.00 126.96 ? 303 PHE A CG  1 
ATOM   2379  C CD1 . PHE A 1 303 ? -45.923 -2.477  3.075   1.00 126.33 ? 303 PHE A CD1 1 
ATOM   2380  C CD2 . PHE A 1 303 ? -47.178 -4.114  4.270   1.00 133.59 ? 303 PHE A CD2 1 
ATOM   2381  C CE1 . PHE A 1 303 ? -44.781 -2.843  3.769   1.00 132.59 ? 303 PHE A CE1 1 
ATOM   2382  C CE2 . PHE A 1 303 ? -46.033 -4.488  4.954   1.00 138.46 ? 303 PHE A CE2 1 
ATOM   2383  C CZ  . PHE A 1 303 ? -44.838 -3.848  4.708   1.00 135.70 ? 303 PHE A CZ  1 
ATOM   2384  N N   . VAL A 1 304 ? -48.503 -5.552  1.057   1.00 127.51 ? 304 VAL A N   1 
ATOM   2385  C CA  . VAL A 1 304 ? -48.077 -6.945  0.997   1.00 123.17 ? 304 VAL A CA  1 
ATOM   2386  C C   . VAL A 1 304 ? -47.412 -7.189  -0.362  1.00 120.46 ? 304 VAL A C   1 
ATOM   2387  O O   . VAL A 1 304 ? -46.376 -7.846  -0.413  1.00 115.34 ? 304 VAL A O   1 
ATOM   2388  C CB  . VAL A 1 304 ? -49.257 -7.909  1.282   1.00 115.02 ? 304 VAL A CB  1 
ATOM   2389  C CG1 . VAL A 1 304 ? -48.926 -9.375  1.040   1.00 105.77 ? 304 VAL A CG1 1 
ATOM   2390  C CG2 . VAL A 1 304 ? -49.800 -7.731  2.695   1.00 107.08 ? 304 VAL A CG2 1 
ATOM   2391  N N   . GLU A 1 305 ? -47.982 -6.626  -1.442  1.00 124.27 ? 305 GLU A N   1 
ATOM   2392  C CA  . GLU A 1 305 ? -47.466 -6.797  -2.795  1.00 122.88 ? 305 GLU A CA  1 
ATOM   2393  C C   . GLU A 1 305 ? -46.053 -6.234  -2.940  1.00 130.55 ? 305 GLU A C   1 
ATOM   2394  O O   . GLU A 1 305 ? -45.243 -6.823  -3.657  1.00 134.19 ? 305 GLU A O   1 
ATOM   2395  C CB  . GLU A 1 305 ? -48.364 -6.099  -3.814  1.00 116.26 ? 305 GLU A CB  1 
ATOM   2396  C CG  . GLU A 1 305 ? -49.704 -6.776  -4.003  1.00 113.97 ? 305 GLU A CG  1 
ATOM   2397  C CD  . GLU A 1 305 ? -50.765 -5.873  -4.604  1.00 111.33 ? 305 GLU A CD  1 
ATOM   2398  O OE1 . GLU A 1 305 ? -50.470 -4.687  -4.876  1.00 100.23 ? 305 GLU A OE1 1 
ATOM   2399  O OE2 . GLU A 1 305 ? -51.896 -6.341  -4.752  1.00 110.85 ? 305 GLU A OE2 1 
ATOM   2400  N N   . GLU A 1 306 ? -45.774 -5.090  -2.290  1.00 130.50 ? 306 GLU A N   1 
ATOM   2401  C CA  . GLU A 1 306 ? -44.450 -4.475  -2.328  1.00 124.74 ? 306 GLU A CA  1 
ATOM   2402  C C   . GLU A 1 306 ? -43.414 -5.398  -1.670  1.00 130.45 ? 306 GLU A C   1 
ATOM   2403  O O   . GLU A 1 306 ? -42.340 -5.609  -2.235  1.00 126.13 ? 306 GLU A O   1 
ATOM   2404  C CB  . GLU A 1 306 ? -44.459 -3.078  -1.689  1.00 121.86 ? 306 GLU A CB  1 
ATOM   2405  C CG  . GLU A 1 306 ? -45.212 -2.011  -2.494  1.00 119.75 ? 306 GLU A CG  1 
ATOM   2406  C CD  . GLU A 1 306 ? -45.068 -0.561  -2.034  1.00 119.33 ? 306 GLU A CD  1 
ATOM   2407  O OE1 . GLU A 1 306 ? -44.088 -0.234  -1.333  1.00 111.78 ? 306 GLU A OE1 1 
ATOM   2408  O OE2 . GLU A 1 306 ? -45.953 0.256   -2.364  1.00 107.05 ? 306 GLU A OE2 1 
ATOM   2409  N N   . THR A 1 307 ? -43.735 -5.959  -0.487  1.00 130.38 ? 307 THR A N   1 
ATOM   2410  C CA  . THR A 1 307 ? -42.830 -6.852  0.236   1.00 118.26 ? 307 THR A CA  1 
ATOM   2411  C C   . THR A 1 307 ? -42.592 -8.142  -0.555  1.00 112.32 ? 307 THR A C   1 
ATOM   2412  O O   . THR A 1 307 ? -41.500 -8.710  -0.486  1.00 97.41  ? 307 THR A O   1 
ATOM   2413  C CB  . THR A 1 307 ? -43.356 -7.243  1.630   1.00 116.68 ? 307 THR A CB  1 
ATOM   2414  O OG1 . THR A 1 307 ? -43.996 -6.138  2.273   1.00 113.02 ? 307 THR A OG1 1 
ATOM   2415  C CG2 . THR A 1 307 ? -42.266 -7.787  2.534   1.00 109.03 ? 307 THR A CG2 1 
ATOM   2416  N N   . LEU A 1 308 ? -43.628 -8.601  -1.281  1.00 111.02 ? 308 LEU A N   1 
ATOM   2417  C CA  . LEU A 1 308 ? -43.633 -9.918  -1.907  1.00 119.32 ? 308 LEU A CA  1 
ATOM   2418  C C   . LEU A 1 308 ? -42.872 -9.901  -3.229  1.00 132.54 ? 308 LEU A C   1 
ATOM   2419  O O   . LEU A 1 308 ? -41.950 -10.695 -3.411  1.00 130.82 ? 308 LEU A O   1 
ATOM   2420  C CB  . LEU A 1 308 ? -45.073 -10.398 -2.136  1.00 114.71 ? 308 LEU A CB  1 
ATOM   2421  C CG  . LEU A 1 308 ? -45.705 -11.222 -1.012  1.00 111.40 ? 308 LEU A CG  1 
ATOM   2422  C CD1 . LEU A 1 308 ? -47.021 -11.835 -1.473  1.00 107.64 ? 308 LEU A CD1 1 
ATOM   2423  C CD2 . LEU A 1 308 ? -44.765 -12.314 -0.507  1.00 106.45 ? 308 LEU A CD2 1 
ATOM   2424  N N   . SER A 1 309 ? -43.274 -9.015  -4.152  1.00 142.42 ? 309 SER A N   1 
ATOM   2425  C CA  . SER A 1 309 ? -42.682 -8.981  -5.483  1.00 140.27 ? 309 SER A CA  1 
ATOM   2426  C C   . SER A 1 309 ? -41.343 -8.232  -5.482  1.00 143.75 ? 309 SER A C   1 
ATOM   2427  O O   . SER A 1 309 ? -40.795 -7.972  -6.553  1.00 136.05 ? 309 SER A O   1 
ATOM   2428  C CB  . SER A 1 309 ? -43.659 -8.436  -6.510  1.00 129.09 ? 309 SER A CB  1 
ATOM   2429  O OG  . SER A 1 309 ? -44.251 -7.222  -6.071  1.00 125.47 ? 309 SER A OG  1 
ATOM   2430  N N   . SER A 1 310 ? -40.808 -7.912  -4.285  1.00 145.62 ? 310 SER A N   1 
ATOM   2431  C CA  . SER A 1 310 ? -39.417 -7.500  -4.125  1.00 137.54 ? 310 SER A CA  1 
ATOM   2432  C C   . SER A 1 310 ? -38.619 -8.524  -3.298  1.00 135.13 ? 310 SER A C   1 
ATOM   2433  O O   . SER A 1 310 ? -37.552 -8.204  -2.774  1.00 127.99 ? 310 SER A O   1 
ATOM   2434  C CB  . SER A 1 310 ? -39.315 -6.082  -3.565  1.00 129.82 ? 310 SER A CB  1 
ATOM   2435  O OG  . SER A 1 310 ? -39.762 -5.993  -2.221  1.00 113.20 ? 310 SER A OG  1 
ATOM   2436  N N   . GLY A 1 311 ? -39.140 -9.757  -3.179  1.00 135.98 ? 311 GLY A N   1 
ATOM   2437  C CA  . GLY A 1 311 ? -38.349 -10.933 -2.829  1.00 131.23 ? 311 GLY A CA  1 
ATOM   2438  C C   . GLY A 1 311 ? -38.190 -11.164 -1.324  1.00 129.94 ? 311 GLY A C   1 
ATOM   2439  O O   . GLY A 1 311 ? -37.061 -11.297 -0.850  1.00 101.96 ? 311 GLY A O   1 
ATOM   2440  N N   . GLN A 1 312 ? -39.317 -11.246 -0.590  1.00 139.41 ? 312 GLN A N   1 
ATOM   2441  C CA  . GLN A 1 312 ? -39.304 -11.467 0.856   1.00 130.63 ? 312 GLN A CA  1 
ATOM   2442  C C   . GLN A 1 312 ? -40.591 -12.158 1.334   1.00 127.61 ? 312 GLN A C   1 
ATOM   2443  O O   . GLN A 1 312 ? -41.663 -11.939 0.763   1.00 112.29 ? 312 GLN A O   1 
ATOM   2444  C CB  . GLN A 1 312 ? -39.101 -10.146 1.612   1.00 119.30 ? 312 GLN A CB  1 
ATOM   2445  C CG  . GLN A 1 312 ? -37.748 -9.486  1.379   1.00 113.38 ? 312 GLN A CG  1 
ATOM   2446  C CD  . GLN A 1 312 ? -37.088 -9.055  2.658   1.00 103.90 ? 312 GLN A CD  1 
ATOM   2447  O OE1 . GLN A 1 312 ? -37.741 -8.618  3.604   1.00 109.01 ? 312 GLN A OE1 1 
ATOM   2448  N NE2 . GLN A 1 312 ? -35.783 -9.246  2.704   1.00 98.57  ? 312 GLN A NE2 1 
ATOM   2449  N N   . VAL A 1 313 ? -40.466 -12.983 2.399   1.00 123.89 ? 313 VAL A N   1 
ATOM   2450  C CA  . VAL A 1 313 ? -41.563 -13.773 2.960   1.00 111.83 ? 313 VAL A CA  1 
ATOM   2451  C C   . VAL A 1 313 ? -42.553 -12.845 3.674   1.00 116.10 ? 313 VAL A C   1 
ATOM   2452  O O   . VAL A 1 313 ? -42.225 -11.703 3.993   1.00 115.42 ? 313 VAL A O   1 
ATOM   2453  C CB  . VAL A 1 313 ? -41.108 -14.920 3.911   1.00 96.54  ? 313 VAL A CB  1 
ATOM   2454  C CG1 . VAL A 1 313 ? -40.361 -16.042 3.189   1.00 83.57  ? 313 VAL A CG1 1 
ATOM   2455  C CG2 . VAL A 1 313 ? -40.317 -14.442 5.132   1.00 92.71  ? 313 VAL A CG2 1 
ATOM   2456  N N   . ILE A 1 314 ? -43.785 -13.348 3.871   1.00 125.08 ? 314 ILE A N   1 
ATOM   2457  C CA  . ILE A 1 314 ? -44.697 -12.891 4.916   1.00 118.53 ? 314 ILE A CA  1 
ATOM   2458  C C   . ILE A 1 314 ? -44.558 -13.870 6.084   1.00 108.00 ? 314 ILE A C   1 
ATOM   2459  O O   . ILE A 1 314 ? -44.879 -15.050 5.928   1.00 103.27 ? 314 ILE A O   1 
ATOM   2460  C CB  . ILE A 1 314 ? -46.158 -12.809 4.404   1.00 116.73 ? 314 ILE A CB  1 
ATOM   2461  C CG1 . ILE A 1 314 ? -46.279 -11.994 3.112   1.00 126.97 ? 314 ILE A CG1 1 
ATOM   2462  C CG2 . ILE A 1 314 ? -47.099 -12.269 5.476   1.00 110.64 ? 314 ILE A CG2 1 
ATOM   2463  C CD1 . ILE A 1 314 ? -46.102 -10.498 3.305   1.00 130.62 ? 314 ILE A CD1 1 
ATOM   2464  N N   . PRO A 1 315 ? -44.070 -13.449 7.279   1.00 115.83 ? 315 PRO A N   1 
ATOM   2465  C CA  . PRO A 1 315 ? -43.864 -14.383 8.392   1.00 117.20 ? 315 PRO A CA  1 
ATOM   2466  C C   . PRO A 1 315 ? -45.170 -14.877 9.029   1.00 105.50 ? 315 PRO A C   1 
ATOM   2467  O O   . PRO A 1 315 ? -46.153 -14.131 9.142   1.00 76.40  ? 315 PRO A O   1 
ATOM   2468  C CB  . PRO A 1 315 ? -43.020 -13.591 9.408   1.00 116.06 ? 315 PRO A CB  1 
ATOM   2469  C CG  . PRO A 1 315 ? -42.593 -12.335 8.666   1.00 124.81 ? 315 PRO A CG  1 
ATOM   2470  C CD  . PRO A 1 315 ? -43.676 -12.078 7.637   1.00 114.79 ? 315 PRO A CD  1 
ATOM   2471  N N   . GLY A 1 316 ? -45.166 -16.163 9.417   1.00 92.97  ? 316 GLY A N   1 
ATOM   2472  C CA  . GLY A 1 316 ? -46.321 -16.788 10.034  1.00 91.07  ? 316 GLY A CA  1 
ATOM   2473  C C   . GLY A 1 316 ? -47.378 -17.213 9.020   1.00 84.65  ? 316 GLY A C   1 
ATOM   2474  O O   . GLY A 1 316 ? -48.473 -17.614 9.418   1.00 72.75  ? 316 GLY A O   1 
ATOM   2475  N N   . TYR A 1 317 ? -47.059 -17.076 7.722   1.00 82.54  ? 317 TYR A N   1 
ATOM   2476  C CA  . TYR A 1 317 ? -47.778 -17.758 6.656   1.00 74.48  ? 317 TYR A CA  1 
ATOM   2477  C C   . TYR A 1 317 ? -46.820 -18.794 6.070   1.00 74.80  ? 317 TYR A C   1 
ATOM   2478  O O   . TYR A 1 317 ? -45.668 -18.451 5.816   1.00 64.63  ? 317 TYR A O   1 
ATOM   2479  C CB  . TYR A 1 317 ? -48.318 -16.729 5.657   1.00 62.70  ? 317 TYR A CB  1 
ATOM   2480  C CG  . TYR A 1 317 ? -49.458 -15.894 6.194   1.00 61.95  ? 317 TYR A CG  1 
ATOM   2481  C CD1 . TYR A 1 317 ? -49.262 -14.883 7.136   1.00 58.89  ? 317 TYR A CD1 1 
ATOM   2482  C CD2 . TYR A 1 317 ? -50.764 -16.134 5.784   1.00 69.69  ? 317 TYR A CD2 1 
ATOM   2483  C CE1 . TYR A 1 317 ? -50.326 -14.149 7.652   1.00 62.63  ? 317 TYR A CE1 1 
ATOM   2484  C CE2 . TYR A 1 317 ? -51.838 -15.387 6.267   1.00 68.27  ? 317 TYR A CE2 1 
ATOM   2485  C CZ  . TYR A 1 317 ? -51.625 -14.389 7.207   1.00 67.07  ? 317 TYR A CZ  1 
ATOM   2486  O OH  . TYR A 1 317 ? -52.738 -13.701 7.672   1.00 64.92  ? 317 TYR A OH  1 
ATOM   2487  N N   . GLY A 1 318 ? -47.269 -20.065 5.965   1.00 76.98  ? 318 GLY A N   1 
ATOM   2488  C CA  . GLY A 1 318 ? -46.533 -21.122 5.275   1.00 80.42  ? 318 GLY A CA  1 
ATOM   2489  C C   . GLY A 1 318 ? -45.881 -22.128 6.231   1.00 86.32  ? 318 GLY A C   1 
ATOM   2490  O O   . GLY A 1 318 ? -45.249 -21.740 7.210   1.00 99.39  ? 318 GLY A O   1 
ATOM   2491  N N   . HIS A 1 319 ? -45.981 -23.425 5.897   1.00 82.45  ? 319 HIS A N   1 
ATOM   2492  C CA  . HIS A 1 319 ? -45.593 -24.512 6.789   1.00 79.38  ? 319 HIS A CA  1 
ATOM   2493  C C   . HIS A 1 319 ? -45.141 -25.717 5.961   1.00 78.33  ? 319 HIS A C   1 
ATOM   2494  O O   . HIS A 1 319 ? -45.616 -25.906 4.837   1.00 81.69  ? 319 HIS A O   1 
ATOM   2495  C CB  . HIS A 1 319 ? -46.781 -24.858 7.708   1.00 81.40  ? 319 HIS A CB  1 
ATOM   2496  C CG  . HIS A 1 319 ? -46.475 -25.661 8.944   1.00 76.76  ? 319 HIS A CG  1 
ATOM   2497  N ND1 . HIS A 1 319 ? -46.272 -27.024 8.952   1.00 66.23  ? 319 HIS A ND1 1 
ATOM   2498  C CD2 . HIS A 1 319 ? -46.400 -25.236 10.244  1.00 71.61  ? 319 HIS A CD2 1 
ATOM   2499  C CE1 . HIS A 1 319 ? -46.054 -27.424 10.201  1.00 68.58  ? 319 HIS A CE1 1 
ATOM   2500  N NE2 . HIS A 1 319 ? -46.120 -26.324 11.026  1.00 72.14  ? 319 HIS A NE2 1 
ATOM   2501  N N   . ALA A 1 320 ? -44.272 -26.562 6.541   1.00 79.24  ? 320 ALA A N   1 
ATOM   2502  C CA  . ALA A 1 320 ? -43.648 -27.657 5.807   1.00 95.17  ? 320 ALA A CA  1 
ATOM   2503  C C   . ALA A 1 320 ? -44.568 -28.878 5.624   1.00 99.71  ? 320 ALA A C   1 
ATOM   2504  O O   . ALA A 1 320 ? -44.149 -29.865 5.018   1.00 101.79 ? 320 ALA A O   1 
ATOM   2505  C CB  . ALA A 1 320 ? -42.366 -28.047 6.507   1.00 103.67 ? 320 ALA A CB  1 
ATOM   2506  N N   . VAL A 1 321 ? -45.773 -28.833 6.191   1.00 98.27  ? 321 VAL A N   1 
ATOM   2507  C CA  . VAL A 1 321 ? -46.741 -29.961 6.064   1.00 86.81  ? 321 VAL A CA  1 
ATOM   2508  C C   . VAL A 1 321 ? -48.121 -29.376 5.770   1.00 78.82  ? 321 VAL A C   1 
ATOM   2509  O O   . VAL A 1 321 ? -48.680 -29.710 4.721   1.00 86.17  ? 321 VAL A O   1 
ATOM   2510  C CB  . VAL A 1 321 ? -46.780 -30.827 7.334   1.00 79.97  ? 321 VAL A CB  1 
ATOM   2511  C CG1 . VAL A 1 321 ? -47.852 -31.900 7.238   1.00 73.23  ? 321 VAL A CG1 1 
ATOM   2512  C CG2 . VAL A 1 321 ? -45.430 -31.448 7.653   1.00 75.59  ? 321 VAL A CG2 1 
ATOM   2513  N N   . LEU A 1 322 ? -48.644 -28.556 6.671   1.00 68.99  ? 322 LEU A N   1 
ATOM   2514  C CA  . LEU A 1 322 ? -49.927 -27.882 6.502   1.00 67.88  ? 322 LEU A CA  1 
ATOM   2515  C C   . LEU A 1 322 ? -50.054 -27.305 5.100   1.00 66.70  ? 322 LEU A C   1 
ATOM   2516  O O   . LEU A 1 322 ? -49.084 -26.742 4.591   1.00 70.31  ? 322 LEU A O   1 
ATOM   2517  C CB  . LEU A 1 322 ? -50.034 -26.741 7.514   1.00 64.70  ? 322 LEU A CB  1 
ATOM   2518  C CG  . LEU A 1 322 ? -50.627 -27.109 8.866   1.00 65.74  ? 322 LEU A CG  1 
ATOM   2519  C CD1 . LEU A 1 322 ? -50.468 -25.955 9.850   1.00 67.61  ? 322 LEU A CD1 1 
ATOM   2520  C CD2 . LEU A 1 322 ? -52.090 -27.491 8.716   1.00 70.28  ? 322 LEU A CD2 1 
ATOM   2521  N N   . ARG A 1 323 ? -51.261 -27.458 4.526   1.00 68.60  ? 323 ARG A N   1 
ATOM   2522  C CA  . ARG A 1 323 ? -51.657 -26.838 3.269   1.00 68.43  ? 323 ARG A CA  1 
ATOM   2523  C C   . ARG A 1 323 ? -52.861 -25.911 3.471   1.00 67.12  ? 323 ARG A C   1 
ATOM   2524  O O   . ARG A 1 323 ? -53.216 -25.178 2.556   1.00 60.75  ? 323 ARG A O   1 
ATOM   2525  C CB  . ARG A 1 323 ? -51.961 -27.904 2.203   1.00 77.70  ? 323 ARG A CB  1 
ATOM   2526  C CG  . ARG A 1 323 ? -50.829 -28.198 1.222   1.00 81.83  ? 323 ARG A CG  1 
ATOM   2527  C CD  . ARG A 1 323 ? -49.814 -29.199 1.744   1.00 94.77  ? 323 ARG A CD  1 
ATOM   2528  N NE  . ARG A 1 323 ? -48.507 -29.093 1.100   1.00 110.66 ? 323 ARG A NE  1 
ATOM   2529  C CZ  . ARG A 1 323 ? -47.352 -28.800 1.715   1.00 113.38 ? 323 ARG A CZ  1 
ATOM   2530  N NH1 . ARG A 1 323 ? -47.320 -28.045 2.808   1.00 98.86  ? 323 ARG A NH1 1 
ATOM   2531  N NH2 . ARG A 1 323 ? -46.214 -29.248 1.205   1.00 104.32 ? 323 ARG A NH2 1 
ATOM   2532  N N   . LYS A 1 324 ? -53.472 -25.898 4.669   1.00 74.60  ? 324 LYS A N   1 
ATOM   2533  C CA  . LYS A 1 324 ? -54.604 -25.014 4.937   1.00 76.45  ? 324 LYS A CA  1 
ATOM   2534  C C   . LYS A 1 324 ? -54.368 -24.138 6.169   1.00 73.03  ? 324 LYS A C   1 
ATOM   2535  O O   . LYS A 1 324 ? -53.303 -24.186 6.789   1.00 68.37  ? 324 LYS A O   1 
ATOM   2536  C CB  . LYS A 1 324 ? -55.884 -25.820 5.166   1.00 79.59  ? 324 LYS A CB  1 
ATOM   2537  C CG  . LYS A 1 324 ? -56.375 -26.622 3.971   1.00 83.34  ? 324 LYS A CG  1 
ATOM   2538  C CD  . LYS A 1 324 ? -56.885 -25.779 2.835   1.00 86.55  ? 324 LYS A CD  1 
ATOM   2539  C CE  . LYS A 1 324 ? -57.940 -26.519 2.042   1.00 96.55  ? 324 LYS A CE  1 
ATOM   2540  N NZ  . LYS A 1 324 ? -57.863 -26.178 0.608   1.00 103.07 ? 324 LYS A NZ  1 
ATOM   2541  N N   . THR A 1 325 ? -55.378 -23.308 6.485   1.00 70.73  ? 325 THR A N   1 
ATOM   2542  C CA  . THR A 1 325 ? -55.427 -22.533 7.717   1.00 72.47  ? 325 THR A CA  1 
ATOM   2543  C C   . THR A 1 325 ? -55.119 -23.485 8.874   1.00 70.79  ? 325 THR A C   1 
ATOM   2544  O O   . THR A 1 325 ? -55.662 -24.593 8.909   1.00 61.84  ? 325 THR A O   1 
ATOM   2545  C CB  . THR A 1 325 ? -56.790 -21.827 7.882   1.00 73.36  ? 325 THR A CB  1 
ATOM   2546  O OG1 . THR A 1 325 ? -57.056 -20.938 6.796   1.00 77.73  ? 325 THR A OG1 1 
ATOM   2547  C CG2 . THR A 1 325 ? -56.895 -20.980 9.128   1.00 70.39  ? 325 THR A CG2 1 
ATOM   2548  N N   . ASP A 1 326 ? -54.223 -23.062 9.787   1.00 57.66  ? 326 ASP A N   1 
ATOM   2549  C CA  . ASP A 1 326 ? -53.987 -23.787 11.026  1.00 52.61  ? 326 ASP A CA  1 
ATOM   2550  C C   . ASP A 1 326 ? -55.155 -23.569 11.990  1.00 50.21  ? 326 ASP A C   1 
ATOM   2551  O O   . ASP A 1 326 ? -55.449 -22.441 12.371  1.00 45.77  ? 326 ASP A O   1 
ATOM   2552  C CB  . ASP A 1 326 ? -52.690 -23.327 11.687  1.00 52.97  ? 326 ASP A CB  1 
ATOM   2553  C CG  . ASP A 1 326 ? -52.137 -24.261 12.758  1.00 56.56  ? 326 ASP A CG  1 
ATOM   2554  O OD1 . ASP A 1 326 ? -52.861 -25.209 13.204  1.00 63.85  ? 326 ASP A OD1 1 
ATOM   2555  O OD2 . ASP A 1 326 ? -50.953 -24.076 13.104  1.00 51.23  ? 326 ASP A OD2 1 
ATOM   2556  N N   . PRO A 1 327 ? -55.859 -24.628 12.455  1.00 53.16  ? 327 PRO A N   1 
ATOM   2557  C CA  . PRO A 1 327 ? -56.957 -24.439 13.418  1.00 56.35  ? 327 PRO A CA  1 
ATOM   2558  C C   . PRO A 1 327 ? -56.501 -23.943 14.795  1.00 53.29  ? 327 PRO A C   1 
ATOM   2559  O O   . PRO A 1 327 ? -57.311 -23.497 15.616  1.00 50.15  ? 327 PRO A O   1 
ATOM   2560  C CB  . PRO A 1 327 ? -57.559 -25.844 13.538  1.00 54.27  ? 327 PRO A CB  1 
ATOM   2561  C CG  . PRO A 1 327 ? -56.400 -26.764 13.186  1.00 57.47  ? 327 PRO A CG  1 
ATOM   2562  C CD  . PRO A 1 327 ? -55.617 -26.042 12.114  1.00 50.99  ? 327 PRO A CD  1 
ATOM   2563  N N   . ARG A 1 328 ? -55.194 -24.097 15.051  1.00 47.63  ? 328 ARG A N   1 
ATOM   2564  C CA  . ARG A 1 328 ? -54.543 -23.468 16.187  1.00 50.93  ? 328 ARG A CA  1 
ATOM   2565  C C   . ARG A 1 328 ? -54.554 -21.952 16.013  1.00 50.77  ? 328 ARG A C   1 
ATOM   2566  O O   . ARG A 1 328 ? -54.863 -21.240 16.962  1.00 52.11  ? 328 ARG A O   1 
ATOM   2567  C CB  . ARG A 1 328 ? -53.112 -23.982 16.343  1.00 51.84  ? 328 ARG A CB  1 
ATOM   2568  C CG  . ARG A 1 328 ? -53.025 -25.462 16.652  1.00 54.17  ? 328 ARG A CG  1 
ATOM   2569  C CD  . ARG A 1 328 ? -51.607 -25.922 16.868  1.00 59.16  ? 328 ARG A CD  1 
ATOM   2570  N NE  . ARG A 1 328 ? -50.752 -25.743 15.709  1.00 62.43  ? 328 ARG A NE  1 
ATOM   2571  C CZ  . ARG A 1 328 ? -49.432 -25.895 15.736  1.00 70.93  ? 328 ARG A CZ  1 
ATOM   2572  N NH1 . ARG A 1 328 ? -48.847 -26.448 16.794  1.00 71.54  ? 328 ARG A NH1 1 
ATOM   2573  N NH2 . ARG A 1 328 ? -48.715 -25.511 14.690  1.00 66.23  ? 328 ARG A NH2 1 
ATOM   2574  N N   . TYR A 1 329 ? -54.241 -21.472 14.797  1.00 54.98  ? 329 TYR A N   1 
ATOM   2575  C CA  . TYR A 1 329 ? -54.439 -20.070 14.446  1.00 57.33  ? 329 TYR A CA  1 
ATOM   2576  C C   . TYR A 1 329 ? -55.889 -19.658 14.749  1.00 56.80  ? 329 TYR A C   1 
ATOM   2577  O O   . TYR A 1 329 ? -56.145 -18.705 15.495  1.00 51.19  ? 329 TYR A O   1 
ATOM   2578  C CB  . TYR A 1 329 ? -53.988 -19.789 12.999  1.00 55.20  ? 329 TYR A CB  1 
ATOM   2579  C CG  . TYR A 1 329 ? -54.239 -18.367 12.558  1.00 61.42  ? 329 TYR A CG  1 
ATOM   2580  C CD1 . TYR A 1 329 ? -55.519 -17.921 12.258  1.00 63.25  ? 329 TYR A CD1 1 
ATOM   2581  C CD2 . TYR A 1 329 ? -53.217 -17.434 12.514  1.00 71.50  ? 329 TYR A CD2 1 
ATOM   2582  C CE1 . TYR A 1 329 ? -55.771 -16.605 11.895  1.00 62.55  ? 329 TYR A CE1 1 
ATOM   2583  C CE2 . TYR A 1 329 ? -53.450 -16.113 12.144  1.00 74.30  ? 329 TYR A CE2 1 
ATOM   2584  C CZ  . TYR A 1 329 ? -54.732 -15.691 11.831  1.00 68.98  ? 329 TYR A CZ  1 
ATOM   2585  O OH  . TYR A 1 329 ? -54.968 -14.372 11.479  1.00 64.86  ? 329 TYR A OH  1 
ATOM   2586  N N   . VAL A 1 330 ? -56.844 -20.413 14.200  1.00 63.21  ? 330 VAL A N   1 
ATOM   2587  C CA  . VAL A 1 330 ? -58.253 -20.062 14.295  1.00 66.73  ? 330 VAL A CA  1 
ATOM   2588  C C   . VAL A 1 330 ? -58.678 -19.911 15.764  1.00 72.22  ? 330 VAL A C   1 
ATOM   2589  O O   . VAL A 1 330 ? -59.494 -19.047 16.076  1.00 79.97  ? 330 VAL A O   1 
ATOM   2590  C CB  . VAL A 1 330 ? -59.137 -21.092 13.560  1.00 69.80  ? 330 VAL A CB  1 
ATOM   2591  C CG1 . VAL A 1 330 ? -60.618 -20.752 13.726  1.00 70.65  ? 330 VAL A CG1 1 
ATOM   2592  C CG2 . VAL A 1 330 ? -58.774 -21.235 12.082  1.00 63.39  ? 330 VAL A CG2 1 
ATOM   2593  N N   . ALA A 1 331 ? -58.149 -20.752 16.669  1.00 67.33  ? 331 ALA A N   1 
ATOM   2594  C CA  . ALA A 1 331 ? -58.562 -20.742 18.069  1.00 58.74  ? 331 ALA A CA  1 
ATOM   2595  C C   . ALA A 1 331 ? -57.999 -19.517 18.785  1.00 56.88  ? 331 ALA A C   1 
ATOM   2596  O O   . ALA A 1 331 ? -58.574 -19.078 19.788  1.00 45.99  ? 331 ALA A O   1 
ATOM   2597  C CB  . ALA A 1 331 ? -58.104 -22.009 18.748  1.00 63.41  ? 331 ALA A CB  1 
ATOM   2598  N N   . GLN A 1 332 ? -56.860 -18.993 18.281  1.00 55.74  ? 332 GLN A N   1 
ATOM   2599  C CA  . GLN A 1 332 ? -56.277 -17.764 18.807  1.00 64.23  ? 332 GLN A CA  1 
ATOM   2600  C C   . GLN A 1 332 ? -57.198 -16.607 18.439  1.00 66.62  ? 332 GLN A C   1 
ATOM   2601  O O   . GLN A 1 332 ? -57.597 -15.822 19.301  1.00 56.96  ? 332 GLN A O   1 
ATOM   2602  C CB  . GLN A 1 332 ? -54.883 -17.476 18.236  1.00 71.08  ? 332 GLN A CB  1 
ATOM   2603  C CG  . GLN A 1 332 ? -53.814 -18.522 18.541  1.00 79.15  ? 332 GLN A CG  1 
ATOM   2604  C CD  . GLN A 1 332 ? -53.270 -18.443 19.949  1.00 80.91  ? 332 GLN A CD  1 
ATOM   2605  O OE1 . GLN A 1 332 ? -54.021 -18.320 20.919  1.00 80.18  ? 332 GLN A OE1 1 
ATOM   2606  N NE2 . GLN A 1 332 ? -51.951 -18.527 20.062  1.00 69.22  ? 332 GLN A NE2 1 
ATOM   2607  N N   . ARG A 1 333 ? -57.541 -16.556 17.141  1.00 68.56  ? 333 ARG A N   1 
ATOM   2608  C CA  . ARG A 1 333 ? -58.473 -15.591 16.577  1.00 64.99  ? 333 ARG A CA  1 
ATOM   2609  C C   . ARG A 1 333 ? -59.774 -15.531 17.392  1.00 61.69  ? 333 ARG A C   1 
ATOM   2610  O O   . ARG A 1 333 ? -60.314 -14.452 17.599  1.00 51.54  ? 333 ARG A O   1 
ATOM   2611  C CB  . ARG A 1 333 ? -58.691 -15.951 15.102  1.00 66.41  ? 333 ARG A CB  1 
ATOM   2612  C CG  . ARG A 1 333 ? -59.613 -14.998 14.366  1.00 72.68  ? 333 ARG A CG  1 
ATOM   2613  C CD  . ARG A 1 333 ? -59.788 -15.322 12.892  1.00 77.20  ? 333 ARG A CD  1 
ATOM   2614  N NE  . ARG A 1 333 ? -60.682 -14.351 12.265  1.00 68.50  ? 333 ARG A NE  1 
ATOM   2615  C CZ  . ARG A 1 333 ? -60.453 -13.044 12.218  1.00 71.19  ? 333 ARG A CZ  1 
ATOM   2616  N NH1 . ARG A 1 333 ? -59.267 -12.574 11.856  1.00 73.15  ? 333 ARG A NH1 1 
ATOM   2617  N NH2 . ARG A 1 333 ? -61.436 -12.213 12.510  1.00 69.71  ? 333 ARG A NH2 1 
ATOM   2618  N N   . GLU A 1 334 ? -60.263 -16.671 17.895  1.00 64.79  ? 334 GLU A N   1 
ATOM   2619  C CA  . GLU A 1 334 ? -61.539 -16.725 18.596  1.00 69.19  ? 334 GLU A CA  1 
ATOM   2620  C C   . GLU A 1 334 ? -61.419 -16.115 19.985  1.00 64.62  ? 334 GLU A C   1 
ATOM   2621  O O   . GLU A 1 334 ? -62.309 -15.378 20.396  1.00 67.54  ? 334 GLU A O   1 
ATOM   2622  C CB  . GLU A 1 334 ? -62.066 -18.157 18.639  1.00 74.30  ? 334 GLU A CB  1 
ATOM   2623  C CG  . GLU A 1 334 ? -62.160 -18.755 17.242  1.00 89.66  ? 334 GLU A CG  1 
ATOM   2624  C CD  . GLU A 1 334 ? -63.233 -19.803 17.012  1.00 96.25  ? 334 GLU A CD  1 
ATOM   2625  O OE1 . GLU A 1 334 ? -63.219 -20.422 15.911  1.00 91.61  ? 334 GLU A OE1 1 
ATOM   2626  O OE2 . GLU A 1 334 ? -64.085 -19.990 17.923  1.00 98.36  ? 334 GLU A OE2 1 
ATOM   2627  N N   . PHE A 1 335 ? -60.318 -16.416 20.683  1.00 62.57  ? 335 PHE A N   1 
ATOM   2628  C CA  . PHE A 1 335 ? -59.978 -15.744 21.931  1.00 58.76  ? 335 PHE A CA  1 
ATOM   2629  C C   . PHE A 1 335 ? -59.906 -14.216 21.748  1.00 55.70  ? 335 PHE A C   1 
ATOM   2630  O O   . PHE A 1 335 ? -60.368 -13.442 22.600  1.00 44.88  ? 335 PHE A O   1 
ATOM   2631  C CB  . PHE A 1 335 ? -58.634 -16.249 22.489  1.00 59.89  ? 335 PHE A CB  1 
ATOM   2632  C CG  . PHE A 1 335 ? -58.385 -15.771 23.901  1.00 58.39  ? 335 PHE A CG  1 
ATOM   2633  C CD1 . PHE A 1 335 ? -59.011 -16.396 24.984  1.00 63.80  ? 335 PHE A CD1 1 
ATOM   2634  C CD2 . PHE A 1 335 ? -57.638 -14.625 24.146  1.00 54.13  ? 335 PHE A CD2 1 
ATOM   2635  C CE1 . PHE A 1 335 ? -58.848 -15.924 26.282  1.00 64.07  ? 335 PHE A CE1 1 
ATOM   2636  C CE2 . PHE A 1 335 ? -57.493 -14.145 25.443  1.00 62.39  ? 335 PHE A CE2 1 
ATOM   2637  C CZ  . PHE A 1 335 ? -58.091 -14.797 26.511  1.00 62.46  ? 335 PHE A CZ  1 
ATOM   2638  N N   . ALA A 1 336 ? -59.294 -13.787 20.631  1.00 50.85  ? 336 ALA A N   1 
ATOM   2639  C CA  . ALA A 1 336 ? -58.915 -12.397 20.436  1.00 55.96  ? 336 ALA A CA  1 
ATOM   2640  C C   . ALA A 1 336 ? -60.125 -11.541 20.044  1.00 57.33  ? 336 ALA A C   1 
ATOM   2641  O O   . ALA A 1 336 ? -60.215 -10.394 20.466  1.00 61.04  ? 336 ALA A O   1 
ATOM   2642  C CB  . ALA A 1 336 ? -57.794 -12.320 19.420  1.00 52.96  ? 336 ALA A CB  1 
ATOM   2643  N N   . LEU A 1 337 ? -61.036 -12.092 19.230  1.00 57.57  ? 337 LEU A N   1 
ATOM   2644  C CA  . LEU A 1 337 ? -62.307 -11.447 18.918  1.00 67.36  ? 337 LEU A CA  1 
ATOM   2645  C C   . LEU A 1 337 ? -63.099 -11.197 20.204  1.00 71.37  ? 337 LEU A C   1 
ATOM   2646  O O   . LEU A 1 337 ? -63.627 -10.101 20.398  1.00 74.77  ? 337 LEU A O   1 
ATOM   2647  C CB  . LEU A 1 337 ? -63.110 -12.332 17.952  1.00 76.62  ? 337 LEU A CB  1 
ATOM   2648  C CG  . LEU A 1 337 ? -62.636 -12.354 16.496  1.00 82.20  ? 337 LEU A CG  1 
ATOM   2649  C CD1 . LEU A 1 337 ? -63.223 -13.543 15.734  1.00 77.37  ? 337 LEU A CD1 1 
ATOM   2650  C CD2 . LEU A 1 337 ? -62.992 -11.050 15.792  1.00 83.78  ? 337 LEU A CD2 1 
ATOM   2651  N N   . LYS A 1 338 ? -63.169 -12.209 21.081  1.00 69.99  ? 338 LYS A N   1 
ATOM   2652  C CA  . LYS A 1 338 ? -63.879 -12.090 22.346  1.00 82.47  ? 338 LYS A CA  1 
ATOM   2653  C C   . LYS A 1 338 ? -63.263 -11.013 23.250  1.00 81.35  ? 338 LYS A C   1 
ATOM   2654  O O   . LYS A 1 338 ? -64.006 -10.258 23.875  1.00 83.62  ? 338 LYS A O   1 
ATOM   2655  C CB  . LYS A 1 338 ? -63.888 -13.427 23.100  1.00 92.82  ? 338 LYS A CB  1 
ATOM   2656  C CG  . LYS A 1 338 ? -64.962 -14.436 22.714  1.00 106.30 ? 338 LYS A CG  1 
ATOM   2657  C CD  . LYS A 1 338 ? -65.462 -15.217 23.914  1.00 105.60 ? 338 LYS A CD  1 
ATOM   2658  C CE  . LYS A 1 338 ? -66.304 -14.348 24.829  1.00 101.30 ? 338 LYS A CE  1 
ATOM   2659  N NZ  . LYS A 1 338 ? -65.894 -14.492 26.243  1.00 96.84  ? 338 LYS A NZ  1 
ATOM   2660  N N   . HIS A 1 339 ? -61.919 -10.946 23.324  1.00 78.37  ? 339 HIS A N   1 
ATOM   2661  C CA  . HIS A 1 339 ? -61.223 -10.369 24.474  1.00 71.86  ? 339 HIS A CA  1 
ATOM   2662  C C   . HIS A 1 339 ? -60.422 -9.103  24.163  1.00 69.64  ? 339 HIS A C   1 
ATOM   2663  O O   . HIS A 1 339 ? -59.998 -8.394  25.076  1.00 56.57  ? 339 HIS A O   1 
ATOM   2664  C CB  . HIS A 1 339 ? -60.293 -11.429 25.061  1.00 68.82  ? 339 HIS A CB  1 
ATOM   2665  C CG  . HIS A 1 339 ? -60.999 -12.419 25.927  1.00 67.43  ? 339 HIS A CG  1 
ATOM   2666  N ND1 . HIS A 1 339 ? -61.328 -12.175 27.237  1.00 65.27  ? 339 HIS A ND1 1 
ATOM   2667  C CD2 . HIS A 1 339 ? -61.437 -13.671 25.620  1.00 61.36  ? 339 HIS A CD2 1 
ATOM   2668  C CE1 . HIS A 1 339 ? -61.951 -13.242 27.725  1.00 71.73  ? 339 HIS A CE1 1 
ATOM   2669  N NE2 . HIS A 1 339 ? -62.026 -14.185 26.739  1.00 70.04  ? 339 HIS A NE2 1 
ATOM   2670  N N   . MET A 1 340 ? -60.145 -8.858  22.883  1.00 72.54  ? 340 MET A N   1 
ATOM   2671  C CA  . MET A 1 340 ? -59.329 -7.729  22.486  1.00 72.55  ? 340 MET A CA  1 
ATOM   2672  C C   . MET A 1 340 ? -59.657 -7.384  21.033  1.00 84.54  ? 340 MET A C   1 
ATOM   2673  O O   . MET A 1 340 ? -58.764 -7.377  20.179  1.00 70.47  ? 340 MET A O   1 
ATOM   2674  C CB  . MET A 1 340 ? -57.832 -8.048  22.644  1.00 73.26  ? 340 MET A CB  1 
ATOM   2675  C CG  . MET A 1 340 ? -57.466 -9.529  22.510  1.00 78.97  ? 340 MET A CG  1 
ATOM   2676  S SD  . MET A 1 340 ? -55.659 -9.910  22.499  1.00 74.00  ? 340 MET A SD  1 
ATOM   2677  C CE  . MET A 1 340 ? -55.124 -9.072  21.009  1.00 73.46  ? 340 MET A CE  1 
ATOM   2678  N N   . PRO A 1 341 ? -60.944 -7.080  20.705  1.00 91.17  ? 341 PRO A N   1 
ATOM   2679  C CA  . PRO A 1 341 ? -61.321 -6.736  19.330  1.00 87.89  ? 341 PRO A CA  1 
ATOM   2680  C C   . PRO A 1 341 ? -60.688 -5.406  18.902  1.00 94.27  ? 341 PRO A C   1 
ATOM   2681  O O   . PRO A 1 341 ? -60.329 -5.225  17.734  1.00 82.00  ? 341 PRO A O   1 
ATOM   2682  C CB  . PRO A 1 341 ? -62.861 -6.700  19.362  1.00 86.46  ? 341 PRO A CB  1 
ATOM   2683  C CG  . PRO A 1 341 ? -63.215 -6.408  20.815  1.00 85.51  ? 341 PRO A CG  1 
ATOM   2684  C CD  . PRO A 1 341 ? -62.092 -7.023  21.634  1.00 89.37  ? 341 PRO A CD  1 
ATOM   2685  N N   . ASP A 1 342 ? -60.491 -4.508  19.884  1.00 96.13  ? 342 ASP A N   1 
ATOM   2686  C CA  . ASP A 1 342 ? -60.098 -3.138  19.613  1.00 97.41  ? 342 ASP A CA  1 
ATOM   2687  C C   . ASP A 1 342 ? -58.587 -2.926  19.732  1.00 86.34  ? 342 ASP A C   1 
ATOM   2688  O O   . ASP A 1 342 ? -58.130 -1.833  19.425  1.00 79.93  ? 342 ASP A O   1 
ATOM   2689  C CB  . ASP A 1 342 ? -60.892 -2.174  20.501  1.00 104.71 ? 342 ASP A CB  1 
ATOM   2690  C CG  . ASP A 1 342 ? -62.381 -2.146  20.179  1.00 107.87 ? 342 ASP A CG  1 
ATOM   2691  O OD1 . ASP A 1 342 ? -62.736 -2.287  18.992  1.00 95.21  ? 342 ASP A OD1 1 
ATOM   2692  O OD2 . ASP A 1 342 ? -63.177 -1.956  21.115  1.00 118.31 ? 342 ASP A OD2 1 
ATOM   2693  N N   . ASP A 1 343 ? -57.807 -3.945  20.129  1.00 78.75  ? 343 ASP A N   1 
ATOM   2694  C CA  . ASP A 1 343 ? -56.351 -3.831  20.151  1.00 81.53  ? 343 ASP A CA  1 
ATOM   2695  C C   . ASP A 1 343 ? -55.852 -3.530  18.734  1.00 75.53  ? 343 ASP A C   1 
ATOM   2696  O O   . ASP A 1 343 ? -56.253 -4.207  17.779  1.00 67.35  ? 343 ASP A O   1 
ATOM   2697  C CB  . ASP A 1 343 ? -55.689 -5.088  20.746  1.00 88.68  ? 343 ASP A CB  1 
ATOM   2698  C CG  . ASP A 1 343 ? -54.166 -5.196  20.656  1.00 82.81  ? 343 ASP A CG  1 
ATOM   2699  O OD1 . ASP A 1 343 ? -53.649 -5.478  19.557  1.00 88.42  ? 343 ASP A OD1 1 
ATOM   2700  O OD2 . ASP A 1 343 ? -53.502 -5.054  21.693  1.00 74.20  ? 343 ASP A OD2 1 
ATOM   2701  N N   . PRO A 1 344 ? -54.969 -2.507  18.565  1.00 70.11  ? 344 PRO A N   1 
ATOM   2702  C CA  . PRO A 1 344 ? -54.430 -2.139  17.254  1.00 67.85  ? 344 PRO A CA  1 
ATOM   2703  C C   . PRO A 1 344 ? -53.748 -3.263  16.472  1.00 67.89  ? 344 PRO A C   1 
ATOM   2704  O O   . PRO A 1 344 ? -53.982 -3.403  15.272  1.00 64.49  ? 344 PRO A O   1 
ATOM   2705  C CB  . PRO A 1 344 ? -53.381 -1.057  17.580  1.00 70.06  ? 344 PRO A CB  1 
ATOM   2706  C CG  . PRO A 1 344 ? -53.810 -0.473  18.904  1.00 71.89  ? 344 PRO A CG  1 
ATOM   2707  C CD  . PRO A 1 344 ? -54.469 -1.621  19.635  1.00 70.60  ? 344 PRO A CD  1 
ATOM   2708  N N   . ILE A 1 345 ? -52.902 -4.050  17.165  1.00 69.46  ? 345 ILE A N   1 
ATOM   2709  C CA  . ILE A 1 345 ? -52.053 -5.061  16.544  1.00 64.62  ? 345 ILE A CA  1 
ATOM   2710  C C   . ILE A 1 345 ? -52.900 -6.270  16.125  1.00 65.71  ? 345 ILE A C   1 
ATOM   2711  O O   . ILE A 1 345 ? -52.651 -6.865  15.074  1.00 55.69  ? 345 ILE A O   1 
ATOM   2712  C CB  . ILE A 1 345 ? -50.863 -5.432  17.461  1.00 61.07  ? 345 ILE A CB  1 
ATOM   2713  C CG1 . ILE A 1 345 ? -50.023 -4.195  17.808  1.00 63.73  ? 345 ILE A CG1 1 
ATOM   2714  C CG2 . ILE A 1 345 ? -50.000 -6.530  16.838  1.00 56.21  ? 345 ILE A CG2 1 
ATOM   2715  C CD1 . ILE A 1 345 ? -48.801 -4.478  18.668  1.00 63.86  ? 345 ILE A CD1 1 
ATOM   2716  N N   . PHE A 1 346 ? -53.914 -6.625  16.928  1.00 66.51  ? 346 PHE A N   1 
ATOM   2717  C CA  . PHE A 1 346 ? -54.860 -7.648  16.516  1.00 74.37  ? 346 PHE A CA  1 
ATOM   2718  C C   . PHE A 1 346 ? -55.590 -7.243  15.232  1.00 75.71  ? 346 PHE A C   1 
ATOM   2719  O O   . PHE A 1 346 ? -55.755 -8.073  14.341  1.00 61.06  ? 346 PHE A O   1 
ATOM   2720  C CB  . PHE A 1 346 ? -55.882 -7.968  17.605  1.00 75.28  ? 346 PHE A CB  1 
ATOM   2721  C CG  . PHE A 1 346 ? -56.947 -8.922  17.123  1.00 79.66  ? 346 PHE A CG  1 
ATOM   2722  C CD1 . PHE A 1 346 ? -56.608 -10.101 16.475  1.00 79.92  ? 346 PHE A CD1 1 
ATOM   2723  C CD2 . PHE A 1 346 ? -58.290 -8.627  17.269  1.00 86.12  ? 346 PHE A CD2 1 
ATOM   2724  C CE1 . PHE A 1 346 ? -57.585 -10.965 15.996  1.00 76.65  ? 346 PHE A CE1 1 
ATOM   2725  C CE2 . PHE A 1 346 ? -59.262 -9.499  16.800  1.00 81.97  ? 346 PHE A CE2 1 
ATOM   2726  C CZ  . PHE A 1 346 ? -58.910 -10.668 16.166  1.00 71.50  ? 346 PHE A CZ  1 
ATOM   2727  N N   . GLN A 1 347 ? -56.030 -5.977  15.139  1.00 82.68  ? 347 GLN A N   1 
ATOM   2728  C CA  . GLN A 1 347 ? -56.747 -5.483  13.966  1.00 75.97  ? 347 GLN A CA  1 
ATOM   2729  C C   . GLN A 1 347 ? -55.911 -5.619  12.695  1.00 70.67  ? 347 GLN A C   1 
ATOM   2730  O O   . GLN A 1 347 ? -56.482 -5.791  11.618  1.00 79.41  ? 347 GLN A O   1 
ATOM   2731  C CB  . GLN A 1 347 ? -57.156 -4.018  14.121  1.00 78.72  ? 347 GLN A CB  1 
ATOM   2732  C CG  . GLN A 1 347 ? -58.379 -3.813  14.993  1.00 78.62  ? 347 GLN A CG  1 
ATOM   2733  C CD  . GLN A 1 347 ? -58.629 -2.359  15.313  1.00 83.17  ? 347 GLN A CD  1 
ATOM   2734  O OE1 . GLN A 1 347 ? -59.356 -2.043  16.249  1.00 96.81  ? 347 GLN A OE1 1 
ATOM   2735  N NE2 . GLN A 1 347 ? -58.012 -1.461  14.560  1.00 83.14  ? 347 GLN A NE2 1 
ATOM   2736  N N   . VAL A 1 348 ? -54.577 -5.551  12.825  1.00 61.90  ? 348 VAL A N   1 
ATOM   2737  C CA  . VAL A 1 348 ? -53.689 -5.726  11.684  1.00 65.02  ? 348 VAL A CA  1 
ATOM   2738  C C   . VAL A 1 348 ? -53.506 -7.205  11.321  1.00 67.93  ? 348 VAL A C   1 
ATOM   2739  O O   . VAL A 1 348 ? -53.373 -7.550  10.145  1.00 64.93  ? 348 VAL A O   1 
ATOM   2740  C CB  . VAL A 1 348 ? -52.341 -5.047  11.954  1.00 64.22  ? 348 VAL A CB  1 
ATOM   2741  C CG1 . VAL A 1 348 ? -51.265 -5.502  10.977  1.00 63.56  ? 348 VAL A CG1 1 
ATOM   2742  C CG2 . VAL A 1 348 ? -52.499 -3.541  11.935  1.00 69.34  ? 348 VAL A CG2 1 
ATOM   2743  N N   . VAL A 1 349 ? -53.447 -8.071  12.336  1.00 74.88  ? 349 VAL A N   1 
ATOM   2744  C CA  . VAL A 1 349 ? -53.470 -9.512  12.129  1.00 85.48  ? 349 VAL A CA  1 
ATOM   2745  C C   . VAL A 1 349 ? -54.786 -9.924  11.467  1.00 83.13  ? 349 VAL A C   1 
ATOM   2746  O O   . VAL A 1 349 ? -54.779 -10.777 10.584  1.00 72.61  ? 349 VAL A O   1 
ATOM   2747  C CB  . VAL A 1 349 ? -53.277 -10.259 13.463  1.00 89.26  ? 349 VAL A CB  1 
ATOM   2748  C CG1 . VAL A 1 349 ? -53.745 -11.706 13.396  1.00 86.05  ? 349 VAL A CG1 1 
ATOM   2749  C CG2 . VAL A 1 349 ? -51.833 -10.171 13.929  1.00 96.20  ? 349 VAL A CG2 1 
ATOM   2750  N N   . SER A 1 350 ? -55.896 -9.326  11.932  1.00 77.90  ? 350 SER A N   1 
ATOM   2751  C CA  . SER A 1 350 ? -57.253 -9.634  11.501  1.00 71.41  ? 350 SER A CA  1 
ATOM   2752  C C   . SER A 1 350 ? -57.433 -9.391  10.002  1.00 71.78  ? 350 SER A C   1 
ATOM   2753  O O   . SER A 1 350 ? -57.904 -10.272 9.266   1.00 64.45  ? 350 SER A O   1 
ATOM   2754  C CB  . SER A 1 350 ? -58.227 -8.823  12.302  1.00 63.98  ? 350 SER A CB  1 
ATOM   2755  O OG  . SER A 1 350 ? -59.536 -9.305  12.119  1.00 59.32  ? 350 SER A OG  1 
ATOM   2756  N N   . MET A 1 351 ? -57.044 -8.177  9.583   1.00 72.96  ? 351 MET A N   1 
ATOM   2757  C CA  . MET A 1 351 ? -57.013 -7.783  8.183   1.00 78.84  ? 351 MET A CA  1 
ATOM   2758  C C   . MET A 1 351 ? -56.075 -8.675  7.366   1.00 76.29  ? 351 MET A C   1 
ATOM   2759  O O   . MET A 1 351 ? -56.442 -9.063  6.260   1.00 83.31  ? 351 MET A O   1 
ATOM   2760  C CB  . MET A 1 351 ? -56.563 -6.325  8.034   1.00 93.96  ? 351 MET A CB  1 
ATOM   2761  C CG  . MET A 1 351 ? -57.706 -5.317  8.051   1.00 105.84 ? 351 MET A CG  1 
ATOM   2762  S SD  . MET A 1 351 ? -57.157 -3.642  8.499   1.00 111.31 ? 351 MET A SD  1 
ATOM   2763  C CE  . MET A 1 351 ? -55.991 -3.336  7.173   1.00 109.93 ? 351 MET A CE  1 
ATOM   2764  N N   . LEU A 1 352 ? -54.870 -8.980  7.886   1.00 77.29  ? 352 LEU A N   1 
ATOM   2765  C CA  . LEU A 1 352 ? -53.915 -9.827  7.172   1.00 76.37  ? 352 LEU A CA  1 
ATOM   2766  C C   . LEU A 1 352 ? -54.525 -11.180 6.800   1.00 76.35  ? 352 LEU A C   1 
ATOM   2767  O O   . LEU A 1 352 ? -54.199 -11.725 5.744   1.00 68.91  ? 352 LEU A O   1 
ATOM   2768  C CB  . LEU A 1 352 ? -52.660 -10.060 8.020   1.00 77.42  ? 352 LEU A CB  1 
ATOM   2769  C CG  . LEU A 1 352 ? -51.613 -8.954  8.018   1.00 76.02  ? 352 LEU A CG  1 
ATOM   2770  C CD1 . LEU A 1 352 ? -50.529 -9.266  9.045   1.00 71.98  ? 352 LEU A CD1 1 
ATOM   2771  C CD2 . LEU A 1 352 ? -51.013 -8.782  6.636   1.00 75.57  ? 352 LEU A CD2 1 
ATOM   2772  N N   . TYR A 1 353 ? -55.353 -11.741 7.696   1.00 80.66  ? 353 TYR A N   1 
ATOM   2773  C CA  . TYR A 1 353 ? -56.044 -13.002 7.461   1.00 85.79  ? 353 TYR A CA  1 
ATOM   2774  C C   . TYR A 1 353 ? -56.846 -12.936 6.159   1.00 94.72  ? 353 TYR A C   1 
ATOM   2775  O O   . TYR A 1 353 ? -56.876 -13.892 5.385   1.00 95.68  ? 353 TYR A O   1 
ATOM   2776  C CB  . TYR A 1 353 ? -56.984 -13.322 8.627   1.00 81.15  ? 353 TYR A CB  1 
ATOM   2777  C CG  . TYR A 1 353 ? -57.548 -14.724 8.640   1.00 79.20  ? 353 TYR A CG  1 
ATOM   2778  C CD1 . TYR A 1 353 ? -56.895 -15.787 8.015   1.00 79.87  ? 353 TYR A CD1 1 
ATOM   2779  C CD2 . TYR A 1 353 ? -58.751 -14.992 9.292   1.00 80.11  ? 353 TYR A CD2 1 
ATOM   2780  C CE1 . TYR A 1 353 ? -57.425 -17.073 8.026   1.00 84.00  ? 353 TYR A CE1 1 
ATOM   2781  C CE2 . TYR A 1 353 ? -59.290 -16.274 9.320   1.00 79.77  ? 353 TYR A CE2 1 
ATOM   2782  C CZ  . TYR A 1 353 ? -58.622 -17.316 8.687   1.00 86.31  ? 353 TYR A CZ  1 
ATOM   2783  O OH  . TYR A 1 353 ? -59.117 -18.601 8.718   1.00 89.89  ? 353 TYR A OH  1 
ATOM   2784  N N   . GLU A 1 354 ? -57.494 -11.786 5.927   1.00 99.99  ? 354 GLU A N   1 
ATOM   2785  C CA  . GLU A 1 354 ? -58.369 -11.591 4.781   1.00 93.17  ? 354 GLU A CA  1 
ATOM   2786  C C   . GLU A 1 354 ? -57.543 -11.436 3.508   1.00 91.70  ? 354 GLU A C   1 
ATOM   2787  O O   . GLU A 1 354 ? -57.786 -12.128 2.513   1.00 89.98  ? 354 GLU A O   1 
ATOM   2788  C CB  . GLU A 1 354 ? -59.251 -10.366 5.030   1.00 89.67  ? 354 GLU A CB  1 
ATOM   2789  C CG  . GLU A 1 354 ? -60.706 -10.570 4.640   1.00 100.24 ? 354 GLU A CG  1 
ATOM   2790  C CD  . GLU A 1 354 ? -61.697 -10.178 5.735   1.00 111.23 ? 354 GLU A CD  1 
ATOM   2791  O OE1 . GLU A 1 354 ? -62.471 -9.222  5.530   1.00 126.77 ? 354 GLU A OE1 1 
ATOM   2792  O OE2 . GLU A 1 354 ? -61.670 -10.828 6.804   1.00 108.92 ? 354 GLU A OE2 1 
ATOM   2793  N N   . VAL A 1 355 ? -56.532 -10.561 3.586   1.00 80.87  ? 355 VAL A N   1 
ATOM   2794  C CA  . VAL A 1 355 ? -55.892 -10.005 2.410   1.00 82.31  ? 355 VAL A CA  1 
ATOM   2795  C C   . VAL A 1 355 ? -54.727 -10.885 1.927   1.00 83.58  ? 355 VAL A C   1 
ATOM   2796  O O   . VAL A 1 355 ? -54.443 -10.899 0.732   1.00 79.29  ? 355 VAL A O   1 
ATOM   2797  C CB  . VAL A 1 355 ? -55.475 -8.548  2.703   1.00 89.06  ? 355 VAL A CB  1 
ATOM   2798  C CG1 . VAL A 1 355 ? -54.036 -8.430  3.166   1.00 95.36  ? 355 VAL A CG1 1 
ATOM   2799  C CG2 . VAL A 1 355 ? -55.697 -7.632  1.509   1.00 103.92 ? 355 VAL A CG2 1 
ATOM   2800  N N   . VAL A 1 356 ? -54.058 -11.627 2.826   1.00 84.29  ? 356 VAL A N   1 
ATOM   2801  C CA  . VAL A 1 356 ? -52.789 -12.275 2.495   1.00 83.93  ? 356 VAL A CA  1 
ATOM   2802  C C   . VAL A 1 356 ? -52.990 -13.606 1.753   1.00 86.89  ? 356 VAL A C   1 
ATOM   2803  O O   . VAL A 1 356 ? -52.168 -13.952 0.901   1.00 71.77  ? 356 VAL A O   1 
ATOM   2804  C CB  . VAL A 1 356 ? -51.890 -12.485 3.733   1.00 77.65  ? 356 VAL A CB  1 
ATOM   2805  C CG1 . VAL A 1 356 ? -50.547 -13.088 3.340   1.00 72.64  ? 356 VAL A CG1 1 
ATOM   2806  C CG2 . VAL A 1 356 ? -51.670 -11.212 4.533   1.00 74.93  ? 356 VAL A CG2 1 
ATOM   2807  N N   . PRO A 1 357 ? -53.999 -14.452 2.080   1.00 94.44  ? 357 PRO A N   1 
ATOM   2808  C CA  . PRO A 1 357 ? -54.246 -15.678 1.311   1.00 95.31  ? 357 PRO A CA  1 
ATOM   2809  C C   . PRO A 1 357 ? -54.648 -15.487 -0.158  1.00 102.36 ? 357 PRO A C   1 
ATOM   2810  O O   . PRO A 1 357 ? -54.113 -16.208 -1.003  1.00 110.45 ? 357 PRO A O   1 
ATOM   2811  C CB  . PRO A 1 357 ? -55.330 -16.425 2.115   1.00 102.25 ? 357 PRO A CB  1 
ATOM   2812  C CG  . PRO A 1 357 ? -55.251 -15.816 3.505   1.00 101.48 ? 357 PRO A CG  1 
ATOM   2813  C CD  . PRO A 1 357 ? -54.858 -14.370 3.274   1.00 97.31  ? 357 PRO A CD  1 
ATOM   2814  N N   . PRO A 1 358 ? -55.583 -14.567 -0.540  1.00 108.59 ? 358 PRO A N   1 
ATOM   2815  C CA  . PRO A 1 358 ? -55.771 -14.212 -1.958  1.00 107.53 ? 358 PRO A CA  1 
ATOM   2816  C C   . PRO A 1 358 ? -54.482 -13.919 -2.745  1.00 99.92  ? 358 PRO A C   1 
ATOM   2817  O O   . PRO A 1 358 ? -54.350 -14.336 -3.895  1.00 87.69  ? 358 PRO A O   1 
ATOM   2818  C CB  . PRO A 1 358 ? -56.684 -12.972 -1.871  1.00 101.24 ? 358 PRO A CB  1 
ATOM   2819  C CG  . PRO A 1 358 ? -57.529 -13.216 -0.635  1.00 94.51  ? 358 PRO A CG  1 
ATOM   2820  C CD  . PRO A 1 358 ? -56.571 -13.888 0.328   1.00 98.04  ? 358 PRO A CD  1 
ATOM   2821  N N   . ILE A 1 359 ? -53.511 -13.254 -2.098  1.00 95.97  ? 359 ILE A N   1 
ATOM   2822  C CA  . ILE A 1 359 ? -52.308 -12.727 -2.736  1.00 91.82  ? 359 ILE A CA  1 
ATOM   2823  C C   . ILE A 1 359 ? -51.202 -13.789 -2.860  1.00 95.72  ? 359 ILE A C   1 
ATOM   2824  O O   . ILE A 1 359 ? -50.466 -13.805 -3.845  1.00 93.36  ? 359 ILE A O   1 
ATOM   2825  C CB  . ILE A 1 359 ? -51.838 -11.471 -1.971  1.00 85.53  ? 359 ILE A CB  1 
ATOM   2826  C CG1 . ILE A 1 359 ? -52.885 -10.356 -2.061  1.00 88.90  ? 359 ILE A CG1 1 
ATOM   2827  C CG2 . ILE A 1 359 ? -50.472 -10.999 -2.449  1.00 86.80  ? 359 ILE A CG2 1 
ATOM   2828  C CD1 . ILE A 1 359 ? -52.574 -9.126  -1.234  1.00 93.51  ? 359 ILE A CD1 1 
ATOM   2829  N N   . LEU A 1 360 ? -51.041 -14.665 -1.859  1.00 98.67  ? 360 LEU A N   1 
ATOM   2830  C CA  . LEU A 1 360 ? -50.094 -15.775 -1.947  1.00 91.38  ? 360 LEU A CA  1 
ATOM   2831  C C   . LEU A 1 360 ? -50.662 -16.875 -2.855  1.00 96.34  ? 360 LEU A C   1 
ATOM   2832  O O   . LEU A 1 360 ? -49.973 -17.840 -3.194  1.00 80.52  ? 360 LEU A O   1 
ATOM   2833  C CB  . LEU A 1 360 ? -49.807 -16.304 -0.534  1.00 88.70  ? 360 LEU A CB  1 
ATOM   2834  C CG  . LEU A 1 360 ? -49.096 -15.350 0.434   1.00 90.27  ? 360 LEU A CG  1 
ATOM   2835  C CD1 . LEU A 1 360 ? -49.243 -15.835 1.866   1.00 93.67  ? 360 LEU A CD1 1 
ATOM   2836  C CD2 . LEU A 1 360 ? -47.618 -15.193 0.101   1.00 86.08  ? 360 LEU A CD2 1 
ATOM   2837  N N   . SER A 1 361 ? -51.935 -16.715 -3.253  1.00 108.76 ? 361 SER A N   1 
ATOM   2838  C CA  . SER A 1 361 ? -52.633 -17.635 -4.141  1.00 105.16 ? 361 SER A CA  1 
ATOM   2839  C C   . SER A 1 361 ? -52.345 -17.309 -5.613  1.00 107.26 ? 361 SER A C   1 
ATOM   2840  O O   . SER A 1 361 ? -52.093 -18.219 -6.404  1.00 94.68  ? 361 SER A O   1 
ATOM   2841  C CB  . SER A 1 361 ? -54.113 -17.594 -3.844  1.00 93.05  ? 361 SER A CB  1 
ATOM   2842  O OG  . SER A 1 361 ? -54.638 -18.903 -3.804  1.00 86.72  ? 361 SER A OG  1 
ATOM   2843  N N   . SER A 1 362 ? -52.401 -16.009 -5.961  1.00 116.78 ? 362 SER A N   1 
ATOM   2844  C CA  . SER A 1 362 ? -51.983 -15.473 -7.256  1.00 121.32 ? 362 SER A CA  1 
ATOM   2845  C C   . SER A 1 362 ? -50.621 -16.015 -7.684  1.00 128.63 ? 362 SER A C   1 
ATOM   2846  O O   . SER A 1 362 ? -50.428 -16.315 -8.861  1.00 134.27 ? 362 SER A O   1 
ATOM   2847  C CB  . SER A 1 362 ? -51.913 -13.956 -7.244  1.00 110.76 ? 362 SER A CB  1 
ATOM   2848  O OG  . SER A 1 362 ? -53.181 -13.370 -7.006  1.00 103.01 ? 362 SER A OG  1 
ATOM   2849  N N   . LEU A 1 363 ? -49.679 -16.084 -6.734  1.00 126.28 ? 363 LEU A N   1 
ATOM   2850  C CA  . LEU A 1 363 ? -48.301 -16.454 -7.017  1.00 126.54 ? 363 LEU A CA  1 
ATOM   2851  C C   . LEU A 1 363 ? -48.151 -17.975 -7.138  1.00 135.81 ? 363 LEU A C   1 
ATOM   2852  O O   . LEU A 1 363 ? -47.163 -18.432 -7.714  1.00 136.24 ? 363 LEU A O   1 
ATOM   2853  C CB  . LEU A 1 363 ? -47.388 -15.893 -5.914  1.00 127.64 ? 363 LEU A CB  1 
ATOM   2854  C CG  . LEU A 1 363 ? -47.532 -14.404 -5.570  1.00 123.44 ? 363 LEU A CG  1 
ATOM   2855  C CD1 . LEU A 1 363 ? -46.278 -13.899 -4.861  1.00 116.75 ? 363 LEU A CD1 1 
ATOM   2856  C CD2 . LEU A 1 363 ? -47.831 -13.548 -6.800  1.00 116.38 ? 363 LEU A CD2 1 
ATOM   2857  N N   . GLY A 1 364 ? -49.111 -18.751 -6.595  1.00 137.12 ? 364 GLY A N   1 
ATOM   2858  C CA  . GLY A 1 364 ? -49.113 -20.209 -6.662  1.00 127.66 ? 364 GLY A CA  1 
ATOM   2859  C C   . GLY A 1 364 ? -47.743 -20.821 -6.363  1.00 133.22 ? 364 GLY A C   1 
ATOM   2860  O O   . GLY A 1 364 ? -47.376 -21.844 -6.942  1.00 123.05 ? 364 GLY A O   1 
ATOM   2861  N N   . LYS A 1 365 ? -47.029 -20.198 -5.414  1.00 140.91 ? 365 LYS A N   1 
ATOM   2862  C CA  . LYS A 1 365 ? -45.584 -20.309 -5.252  1.00 129.89 ? 365 LYS A CA  1 
ATOM   2863  C C   . LYS A 1 365 ? -45.259 -21.245 -4.086  1.00 121.76 ? 365 LYS A C   1 
ATOM   2864  O O   . LYS A 1 365 ? -44.660 -22.301 -4.278  1.00 97.40  ? 365 LYS A O   1 
ATOM   2865  C CB  . LYS A 1 365 ? -45.041 -18.897 -4.995  1.00 131.01 ? 365 LYS A CB  1 
ATOM   2866  C CG  . LYS A 1 365 ? -43.529 -18.722 -4.982  1.00 125.50 ? 365 LYS A CG  1 
ATOM   2867  C CD  . LYS A 1 365 ? -43.030 -17.853 -6.111  1.00 121.61 ? 365 LYS A CD  1 
ATOM   2868  C CE  . LYS A 1 365 ? -41.759 -17.108 -5.765  1.00 114.59 ? 365 LYS A CE  1 
ATOM   2869  N NZ  . LYS A 1 365 ? -41.377 -16.212 -6.887  1.00 116.63 ? 365 LYS A NZ  1 
ATOM   2870  N N   . VAL A 1 366 ? -45.673 -20.834 -2.874  1.00 130.00 ? 366 VAL A N   1 
ATOM   2871  C CA  . VAL A 1 366 ? -45.463 -21.583 -1.641  1.00 124.90 ? 366 VAL A CA  1 
ATOM   2872  C C   . VAL A 1 366 ? -46.644 -22.540 -1.463  1.00 124.47 ? 366 VAL A C   1 
ATOM   2873  O O   . VAL A 1 366 ? -47.793 -22.187 -1.730  1.00 116.67 ? 366 VAL A O   1 
ATOM   2874  C CB  . VAL A 1 366 ? -45.281 -20.652 -0.418  1.00 117.49 ? 366 VAL A CB  1 
ATOM   2875  C CG1 . VAL A 1 366 ? -44.087 -19.716 -0.591  1.00 110.60 ? 366 VAL A CG1 1 
ATOM   2876  C CG2 . VAL A 1 366 ? -46.552 -19.872 -0.079  1.00 103.31 ? 366 VAL A CG2 1 
ATOM   2877  N N   . LYS A 1 367 ? -46.350 -23.753 -0.975  1.00 114.67 ? 367 LYS A N   1 
ATOM   2878  C CA  . LYS A 1 367 ? -47.321 -24.831 -0.951  1.00 106.66 ? 367 LYS A CA  1 
ATOM   2879  C C   . LYS A 1 367 ? -48.360 -24.645 0.171   1.00 109.90 ? 367 LYS A C   1 
ATOM   2880  O O   . LYS A 1 367 ? -49.270 -25.458 0.237   1.00 105.83 ? 367 LYS A O   1 
ATOM   2881  C CB  . LYS A 1 367 ? -46.533 -26.148 -0.893  1.00 93.84  ? 367 LYS A CB  1 
ATOM   2882  N N   . ASP A 1 368 ? -48.244 -23.611 1.040   1.00 108.35 ? 368 ASP A N   1 
ATOM   2883  C CA  . ASP A 1 368 ? -49.239 -23.293 2.072   1.00 95.82  ? 368 ASP A CA  1 
ATOM   2884  C C   . ASP A 1 368 ? -49.544 -21.788 2.050   1.00 96.05  ? 368 ASP A C   1 
ATOM   2885  O O   . ASP A 1 368 ? -48.853 -21.009 2.711   1.00 100.63 ? 368 ASP A O   1 
ATOM   2886  C CB  . ASP A 1 368 ? -48.786 -23.748 3.477   1.00 87.23  ? 368 ASP A CB  1 
ATOM   2887  C CG  . ASP A 1 368 ? -49.750 -23.469 4.645   1.00 84.46  ? 368 ASP A CG  1 
ATOM   2888  O OD1 . ASP A 1 368 ? -50.984 -23.488 4.428   1.00 71.21  ? 368 ASP A OD1 1 
ATOM   2889  O OD2 . ASP A 1 368 ? -49.275 -23.275 5.800   1.00 68.64  ? 368 ASP A OD2 1 
ATOM   2890  N N   . PRO A 1 369 ? -50.598 -21.327 1.326   1.00 95.47  ? 369 PRO A N   1 
ATOM   2891  C CA  . PRO A 1 369 ? -50.919 -19.896 1.220   1.00 95.94  ? 369 PRO A CA  1 
ATOM   2892  C C   . PRO A 1 369 ? -51.744 -19.320 2.373   1.00 100.02 ? 369 PRO A C   1 
ATOM   2893  O O   . PRO A 1 369 ? -52.562 -18.419 2.174   1.00 100.56 ? 369 PRO A O   1 
ATOM   2894  C CB  . PRO A 1 369 ? -51.736 -19.831 -0.083  1.00 90.56  ? 369 PRO A CB  1 
ATOM   2895  C CG  . PRO A 1 369 ? -52.461 -21.162 -0.128  1.00 93.60  ? 369 PRO A CG  1 
ATOM   2896  C CD  . PRO A 1 369 ? -51.518 -22.156 0.529   1.00 95.20  ? 369 PRO A CD  1 
ATOM   2897  N N   . TRP A 1 370 ? -51.485 -19.826 3.587   1.00 102.28 ? 370 TRP A N   1 
ATOM   2898  C CA  . TRP A 1 370 ? -52.388 -19.666 4.718   1.00 87.24  ? 370 TRP A CA  1 
ATOM   2899  C C   . TRP A 1 370 ? -51.571 -19.472 5.995   1.00 80.02  ? 370 TRP A C   1 
ATOM   2900  O O   . TRP A 1 370 ? -50.364 -19.725 6.001   1.00 72.40  ? 370 TRP A O   1 
ATOM   2901  C CB  . TRP A 1 370 ? -53.332 -20.876 4.809   1.00 87.16  ? 370 TRP A CB  1 
ATOM   2902  C CG  . TRP A 1 370 ? -54.350 -20.955 3.709   1.00 90.07  ? 370 TRP A CG  1 
ATOM   2903  C CD1 . TRP A 1 370 ? -54.310 -21.772 2.614   1.00 83.76  ? 370 TRP A CD1 1 
ATOM   2904  C CD2 . TRP A 1 370 ? -55.581 -20.212 3.611   1.00 92.69  ? 370 TRP A CD2 1 
ATOM   2905  N NE1 . TRP A 1 370 ? -55.411 -21.564 1.827   1.00 88.75  ? 370 TRP A NE1 1 
ATOM   2906  C CE2 . TRP A 1 370 ? -56.216 -20.623 2.418   1.00 88.49  ? 370 TRP A CE2 1 
ATOM   2907  C CE3 . TRP A 1 370 ? -56.210 -19.242 4.407   1.00 90.74  ? 370 TRP A CE3 1 
ATOM   2908  C CZ2 . TRP A 1 370 ? -57.448 -20.105 2.017   1.00 80.62  ? 370 TRP A CZ2 1 
ATOM   2909  C CZ3 . TRP A 1 370 ? -57.429 -18.733 4.012   1.00 91.21  ? 370 TRP A CZ3 1 
ATOM   2910  C CH2 . TRP A 1 370 ? -58.038 -19.164 2.832   1.00 84.37  ? 370 TRP A CH2 1 
ATOM   2911  N N   . PRO A 1 371 ? -52.198 -18.983 7.094   1.00 76.81  ? 371 PRO A N   1 
ATOM   2912  C CA  . PRO A 1 371 ? -51.513 -18.799 8.378   1.00 79.37  ? 371 PRO A CA  1 
ATOM   2913  C C   . PRO A 1 371 ? -51.284 -20.063 9.213   1.00 81.31  ? 371 PRO A C   1 
ATOM   2914  O O   . PRO A 1 371 ? -52.074 -21.015 9.127   1.00 65.42  ? 371 PRO A O   1 
ATOM   2915  C CB  . PRO A 1 371 ? -52.458 -17.856 9.152   1.00 75.37  ? 371 PRO A CB  1 
ATOM   2916  C CG  . PRO A 1 371 ? -53.831 -18.127 8.583   1.00 78.58  ? 371 PRO A CG  1 
ATOM   2917  C CD  . PRO A 1 371 ? -53.590 -18.501 7.137   1.00 81.36  ? 371 PRO A CD  1 
ATOM   2918  N N   . ASN A 1 372 ? -50.188 -20.029 10.006  1.00 80.04  ? 372 ASN A N   1 
ATOM   2919  C CA  . ASN A 1 372 ? -49.949 -20.943 11.124  1.00 80.38  ? 372 ASN A CA  1 
ATOM   2920  C C   . ASN A 1 372 ? -50.113 -20.174 12.446  1.00 84.05  ? 372 ASN A C   1 
ATOM   2921  O O   . ASN A 1 372 ? -50.479 -18.996 12.425  1.00 92.75  ? 372 ASN A O   1 
ATOM   2922  C CB  . ASN A 1 372 ? -48.632 -21.723 10.945  1.00 76.94  ? 372 ASN A CB  1 
ATOM   2923  C CG  . ASN A 1 372 ? -47.375 -20.878 10.940  1.00 75.62  ? 372 ASN A CG  1 
ATOM   2924  O OD1 . ASN A 1 372 ? -46.897 -20.459 11.992  1.00 83.53  ? 372 ASN A OD1 1 
ATOM   2925  N ND2 . ASN A 1 372 ? -46.804 -20.658 9.768   1.00 61.59  ? 372 ASN A ND2 1 
ATOM   2926  N N   . VAL A 1 373 ? -49.892 -20.844 13.597  1.00 83.91  ? 373 VAL A N   1 
ATOM   2927  C CA  . VAL A 1 373 ? -50.168 -20.259 14.912  1.00 86.20  ? 373 VAL A CA  1 
ATOM   2928  C C   . VAL A 1 373 ? -49.387 -18.971 15.155  1.00 90.67  ? 373 VAL A C   1 
ATOM   2929  O O   . VAL A 1 373 ? -49.903 -18.063 15.808  1.00 84.36  ? 373 VAL A O   1 
ATOM   2930  C CB  . VAL A 1 373 ? -49.851 -21.188 16.099  1.00 79.52  ? 373 VAL A CB  1 
ATOM   2931  C CG1 . VAL A 1 373 ? -51.086 -21.433 16.945  1.00 86.15  ? 373 VAL A CG1 1 
ATOM   2932  C CG2 . VAL A 1 373 ? -49.138 -22.471 15.704  1.00 68.61  ? 373 VAL A CG2 1 
ATOM   2933  N N   . ASP A 1 374 ? -48.122 -18.957 14.713  1.00 87.05  ? 374 ASP A N   1 
ATOM   2934  C CA  . ASP A 1 374 ? -47.163 -17.915 15.058  1.00 84.46  ? 374 ASP A CA  1 
ATOM   2935  C C   . ASP A 1 374 ? -47.632 -16.542 14.565  1.00 69.50  ? 374 ASP A C   1 
ATOM   2936  O O   . ASP A 1 374 ? -47.222 -15.501 15.096  1.00 66.32  ? 374 ASP A O   1 
ATOM   2937  C CB  . ASP A 1 374 ? -45.796 -18.296 14.498  1.00 95.86  ? 374 ASP A CB  1 
ATOM   2938  C CG  . ASP A 1 374 ? -45.292 -19.639 15.004  1.00 102.44 ? 374 ASP A CG  1 
ATOM   2939  O OD1 . ASP A 1 374 ? -45.295 -19.841 16.244  1.00 94.81  ? 374 ASP A OD1 1 
ATOM   2940  O OD2 . ASP A 1 374 ? -44.902 -20.472 14.159  1.00 109.57 ? 374 ASP A OD2 1 
ATOM   2941  N N   . ALA A 1 375 ? -48.520 -16.556 13.562  1.00 57.39  ? 375 ALA A N   1 
ATOM   2942  C CA  . ALA A 1 375 ? -49.166 -15.357 13.061  1.00 59.80  ? 375 ALA A CA  1 
ATOM   2943  C C   . ALA A 1 375 ? -50.048 -14.693 14.125  1.00 62.97  ? 375 ALA A C   1 
ATOM   2944  O O   . ALA A 1 375 ? -50.282 -13.486 14.044  1.00 67.76  ? 375 ALA A O   1 
ATOM   2945  C CB  . ALA A 1 375 ? -49.963 -15.688 11.822  1.00 66.27  ? 375 ALA A CB  1 
ATOM   2946  N N   . HIS A 1 376 ? -50.526 -15.454 15.125  1.00 61.43  ? 376 HIS A N   1 
ATOM   2947  C CA  . HIS A 1 376 ? -51.531 -14.941 16.044  1.00 61.99  ? 376 HIS A CA  1 
ATOM   2948  C C   . HIS A 1 376 ? -51.098 -14.959 17.520  1.00 60.93  ? 376 HIS A C   1 
ATOM   2949  O O   . HIS A 1 376 ? -51.780 -14.373 18.365  1.00 49.81  ? 376 HIS A O   1 
ATOM   2950  C CB  . HIS A 1 376 ? -52.827 -15.738 15.847  1.00 61.17  ? 376 HIS A CB  1 
ATOM   2951  C CG  . HIS A 1 376 ? -54.063 -14.911 15.981  1.00 63.25  ? 376 HIS A CG  1 
ATOM   2952  N ND1 . HIS A 1 376 ? -54.284 -14.045 17.016  1.00 67.58  ? 376 HIS A ND1 1 
ATOM   2953  C CD2 . HIS A 1 376 ? -55.126 -14.812 15.137  1.00 69.54  ? 376 HIS A CD2 1 
ATOM   2954  C CE1 . HIS A 1 376 ? -55.457 -13.447 16.839  1.00 76.03  ? 376 HIS A CE1 1 
ATOM   2955  N NE2 . HIS A 1 376 ? -55.997 -13.906 15.669  1.00 78.26  ? 376 HIS A NE2 1 
ATOM   2956  N N   . SER A 1 377 ? -49.996 -15.643 17.853  1.00 56.72  ? 377 SER A N   1 
ATOM   2957  C CA  . SER A 1 377 ? -49.631 -15.880 19.248  1.00 71.20  ? 377 SER A CA  1 
ATOM   2958  C C   . SER A 1 377 ? -49.186 -14.591 19.957  1.00 69.31  ? 377 SER A C   1 
ATOM   2959  O O   . SER A 1 377 ? -49.669 -14.254 21.045  1.00 64.79  ? 377 SER A O   1 
ATOM   2960  C CB  . SER A 1 377 ? -48.558 -16.948 19.342  1.00 72.34  ? 377 SER A CB  1 
ATOM   2961  O OG  . SER A 1 377 ? -49.051 -18.227 18.959  1.00 76.49  ? 377 SER A OG  1 
ATOM   2962  N N   . GLY A 1 378 ? -48.264 -13.873 19.306  1.00 69.22  ? 378 GLY A N   1 
ATOM   2963  C CA  . GLY A 1 378 ? -47.502 -12.806 19.926  1.00 65.14  ? 378 GLY A CA  1 
ATOM   2964  C C   . GLY A 1 378 ? -48.363 -11.602 20.273  1.00 62.93  ? 378 GLY A C   1 
ATOM   2965  O O   . GLY A 1 378 ? -48.114 -10.944 21.284  1.00 50.75  ? 378 GLY A O   1 
ATOM   2966  N N   . CYS A 1 379 ? -49.375 -11.330 19.437  1.00 64.17  ? 379 CYS A N   1 
ATOM   2967  C CA  . CYS A 1 379 ? -50.193 -10.142 19.634  1.00 68.41  ? 379 CYS A CA  1 
ATOM   2968  C C   . CYS A 1 379 ? -51.023 -10.266 20.915  1.00 64.56  ? 379 CYS A C   1 
ATOM   2969  O O   . CYS A 1 379 ? -51.310 -9.269  21.581  1.00 64.01  ? 379 CYS A O   1 
ATOM   2970  C CB  . CYS A 1 379 ? -51.044 -9.823  18.407  1.00 77.11  ? 379 CYS A CB  1 
ATOM   2971  S SG  . CYS A 1 379 ? -52.388 -10.984 18.068  1.00 77.02  ? 379 CYS A SG  1 
ATOM   2972  N N   . ILE A 1 380 ? -51.348 -11.507 21.294  1.00 61.88  ? 380 ILE A N   1 
ATOM   2973  C CA  . ILE A 1 380 ? -52.144 -11.761 22.482  1.00 54.03  ? 380 ILE A CA  1 
ATOM   2974  C C   . ILE A 1 380 ? -51.273 -11.592 23.725  1.00 50.00  ? 380 ILE A C   1 
ATOM   2975  O O   . ILE A 1 380 ? -51.708 -10.998 24.714  1.00 54.36  ? 380 ILE A O   1 
ATOM   2976  C CB  . ILE A 1 380 ? -52.773 -13.159 22.395  1.00 51.82  ? 380 ILE A CB  1 
ATOM   2977  C CG1 . ILE A 1 380 ? -53.732 -13.274 21.204  1.00 52.79  ? 380 ILE A CG1 1 
ATOM   2978  C CG2 . ILE A 1 380 ? -53.452 -13.495 23.703  1.00 52.28  ? 380 ILE A CG2 1 
ATOM   2979  C CD1 . ILE A 1 380 ? -54.349 -14.650 21.026  1.00 55.16  ? 380 ILE A CD1 1 
ATOM   2980  N N   . GLN A 1 381 ? -50.053 -12.141 23.663  1.00 45.99  ? 381 GLN A N   1 
ATOM   2981  C CA  . GLN A 1 381 ? -49.063 -11.994 24.725  1.00 49.80  ? 381 GLN A CA  1 
ATOM   2982  C C   . GLN A 1 381 ? -48.797 -10.503 24.932  1.00 51.05  ? 381 GLN A C   1 
ATOM   2983  O O   . GLN A 1 381 ? -48.864 -9.990  26.046  1.00 52.31  ? 381 GLN A O   1 
ATOM   2984  C CB  . GLN A 1 381 ? -47.733 -12.693 24.372  1.00 48.87  ? 381 GLN A CB  1 
ATOM   2985  C CG  . GLN A 1 381 ? -47.786 -14.209 24.191  1.00 44.32  ? 381 GLN A CG  1 
ATOM   2986  C CD  . GLN A 1 381 ? -48.428 -14.908 25.366  1.00 47.55  ? 381 GLN A CD  1 
ATOM   2987  O OE1 . GLN A 1 381 ? -49.275 -15.797 25.193  1.00 37.95  ? 381 GLN A OE1 1 
ATOM   2988  N NE2 . GLN A 1 381 ? -48.013 -14.506 26.572  1.00 42.58  ? 381 GLN A NE2 1 
ATOM   2989  N N   . TRP A 1 382 ? -48.483 -9.819  23.826  1.00 54.56  ? 382 TRP A N   1 
ATOM   2990  C CA  . TRP A 1 382 ? -48.175 -8.403  23.850  1.00 50.47  ? 382 TRP A CA  1 
ATOM   2991  C C   . TRP A 1 382 ? -49.269 -7.628  24.574  1.00 49.01  ? 382 TRP A C   1 
ATOM   2992  O O   . TRP A 1 382 ? -48.971 -6.787  25.413  1.00 46.13  ? 382 TRP A O   1 
ATOM   2993  C CB  . TRP A 1 382 ? -47.988 -7.874  22.428  1.00 51.97  ? 382 TRP A CB  1 
ATOM   2994  C CG  . TRP A 1 382 ? -47.495 -6.462  22.430  1.00 61.11  ? 382 TRP A CG  1 
ATOM   2995  C CD1 . TRP A 1 382 ? -48.235 -5.315  22.490  1.00 58.11  ? 382 TRP A CD1 1 
ATOM   2996  C CD2 . TRP A 1 382 ? -46.113 -6.057  22.482  1.00 66.79  ? 382 TRP A CD2 1 
ATOM   2997  N NE1 . TRP A 1 382 ? -47.407 -4.223  22.513  1.00 59.56  ? 382 TRP A NE1 1 
ATOM   2998  C CE2 . TRP A 1 382 ? -46.100 -4.645  22.521  1.00 60.00  ? 382 TRP A CE2 1 
ATOM   2999  C CE3 . TRP A 1 382 ? -44.895 -6.753  22.464  1.00 61.79  ? 382 TRP A CE3 1 
ATOM   3000  C CZ2 . TRP A 1 382 ? -44.909 -3.921  22.549  1.00 58.99  ? 382 TRP A CZ2 1 
ATOM   3001  C CZ3 . TRP A 1 382 ? -43.719 -6.036  22.492  1.00 60.02  ? 382 TRP A CZ3 1 
ATOM   3002  C CH2 . TRP A 1 382 ? -43.729 -4.637  22.530  1.00 63.29  ? 382 TRP A CH2 1 
ATOM   3003  N N   . HIS A 1 383 ? -50.528 -7.911  24.229  1.00 46.43  ? 383 HIS A N   1 
ATOM   3004  C CA  . HIS A 1 383 ? -51.643 -7.169  24.777  1.00 45.57  ? 383 HIS A CA  1 
ATOM   3005  C C   . HIS A 1 383 ? -51.683 -7.297  26.298  1.00 44.63  ? 383 HIS A C   1 
ATOM   3006  O O   . HIS A 1 383 ? -52.137 -6.372  26.971  1.00 40.21  ? 383 HIS A O   1 
ATOM   3007  C CB  . HIS A 1 383 ? -52.979 -7.615  24.162  1.00 52.28  ? 383 HIS A CB  1 
ATOM   3008  C CG  . HIS A 1 383 ? -54.198 -6.989  24.787  1.00 56.42  ? 383 HIS A CG  1 
ATOM   3009  N ND1 . HIS A 1 383 ? -54.826 -5.868  24.291  1.00 54.63  ? 383 HIS A ND1 1 
ATOM   3010  C CD2 . HIS A 1 383 ? -54.876 -7.356  25.919  1.00 56.93  ? 383 HIS A CD2 1 
ATOM   3011  C CE1 . HIS A 1 383 ? -55.863 -5.565  25.071  1.00 60.17  ? 383 HIS A CE1 1 
ATOM   3012  N NE2 . HIS A 1 383 ? -55.912 -6.476  26.093  1.00 58.35  ? 383 HIS A NE2 1 
ATOM   3013  N N   . TYR A 1 384 ? -51.220 -8.424  26.853  1.00 42.94  ? 384 TYR A N   1 
ATOM   3014  C CA  . TYR A 1 384 ? -51.283 -8.606  28.307  1.00 49.79  ? 384 TYR A CA  1 
ATOM   3015  C C   . TYR A 1 384 ? -49.971 -8.249  28.996  1.00 47.94  ? 384 TYR A C   1 
ATOM   3016  O O   . TYR A 1 384 ? -49.850 -8.484  30.185  1.00 49.86  ? 384 TYR A O   1 
ATOM   3017  C CB  . TYR A 1 384 ? -51.759 -10.016 28.666  1.00 50.56  ? 384 TYR A CB  1 
ATOM   3018  C CG  . TYR A 1 384 ? -53.187 -10.238 28.243  1.00 54.55  ? 384 TYR A CG  1 
ATOM   3019  C CD1 . TYR A 1 384 ? -54.232 -9.650  28.943  1.00 58.67  ? 384 TYR A CD1 1 
ATOM   3020  C CD2 . TYR A 1 384 ? -53.485 -10.923 27.078  1.00 50.19  ? 384 TYR A CD2 1 
ATOM   3021  C CE1 . TYR A 1 384 ? -55.547 -9.805  28.538  1.00 60.29  ? 384 TYR A CE1 1 
ATOM   3022  C CE2 . TYR A 1 384 ? -54.795 -11.084 26.663  1.00 59.67  ? 384 TYR A CE2 1 
ATOM   3023  C CZ  . TYR A 1 384 ? -55.829 -10.534 27.398  1.00 59.94  ? 384 TYR A CZ  1 
ATOM   3024  O OH  . TYR A 1 384 ? -57.129 -10.685 26.977  1.00 69.55  ? 384 TYR A OH  1 
ATOM   3025  N N   . GLY A 1 385 ? -49.021 -7.645  28.266  1.00 51.74  ? 385 GLY A N   1 
ATOM   3026  C CA  . GLY A 1 385 ? -47.819 -7.091  28.879  1.00 49.14  ? 385 GLY A CA  1 
ATOM   3027  C C   . GLY A 1 385 ? -46.605 -8.020  28.801  1.00 45.82  ? 385 GLY A C   1 
ATOM   3028  O O   . GLY A 1 385 ? -45.539 -7.685  29.299  1.00 42.69  ? 385 GLY A O   1 
ATOM   3029  N N   . VAL A 1 386 ? -46.747 -9.176  28.150  1.00 43.27  ? 386 VAL A N   1 
ATOM   3030  C CA  . VAL A 1 386 ? -45.580 -9.994  27.870  1.00 48.86  ? 386 VAL A CA  1 
ATOM   3031  C C   . VAL A 1 386 ? -44.945 -9.427  26.602  1.00 47.70  ? 386 VAL A C   1 
ATOM   3032  O O   . VAL A 1 386 ? -45.238 -9.868  25.489  1.00 42.66  ? 386 VAL A O   1 
ATOM   3033  C CB  . VAL A 1 386 ? -45.926 -11.498 27.767  1.00 47.56  ? 386 VAL A CB  1 
ATOM   3034  C CG1 . VAL A 1 386 ? -44.698 -12.397 27.691  1.00 44.32  ? 386 VAL A CG1 1 
ATOM   3035  C CG2 . VAL A 1 386 ? -46.811 -11.929 28.918  1.00 44.62  ? 386 VAL A CG2 1 
ATOM   3036  N N   . VAL A 1 387 ? -44.088 -8.418  26.809  1.00 44.38  ? 387 VAL A N   1 
ATOM   3037  C CA  . VAL A 1 387 ? -43.509 -7.635  25.726  1.00 48.16  ? 387 VAL A CA  1 
ATOM   3038  C C   . VAL A 1 387 ? -42.095 -8.117  25.380  1.00 48.10  ? 387 VAL A C   1 
ATOM   3039  O O   . VAL A 1 387 ? -41.485 -7.607  24.443  1.00 42.51  ? 387 VAL A O   1 
ATOM   3040  C CB  . VAL A 1 387 ? -43.527 -6.142  26.098  1.00 49.84  ? 387 VAL A CB  1 
ATOM   3041  C CG1 . VAL A 1 387 ? -44.950 -5.680  26.379  1.00 52.26  ? 387 VAL A CG1 1 
ATOM   3042  C CG2 . VAL A 1 387 ? -42.599 -5.815  27.265  1.00 47.36  ? 387 VAL A CG2 1 
ATOM   3043  N N   . GLU A 1 388 ? -41.608 -9.112  26.131  1.00 48.06  ? 388 GLU A N   1 
ATOM   3044  C CA  . GLU A 1 388 ? -40.251 -9.616  26.035  1.00 42.80  ? 388 GLU A CA  1 
ATOM   3045  C C   . GLU A 1 388 ? -40.245 -10.778 25.045  1.00 44.79  ? 388 GLU A C   1 
ATOM   3046  O O   . GLU A 1 388 ? -40.502 -11.932 25.397  1.00 53.72  ? 388 GLU A O   1 
ATOM   3047  C CB  . GLU A 1 388 ? -39.780 -9.975  27.440  1.00 45.67  ? 388 GLU A CB  1 
ATOM   3048  C CG  . GLU A 1 388 ? -39.934 -8.823  28.453  1.00 49.83  ? 388 GLU A CG  1 
ATOM   3049  C CD  . GLU A 1 388 ? -41.245 -8.643  29.233  1.00 53.14  ? 388 GLU A CD  1 
ATOM   3050  O OE1 . GLU A 1 388 ? -42.275 -9.326  28.933  1.00 45.50  ? 388 GLU A OE1 1 
ATOM   3051  O OE2 . GLU A 1 388 ? -41.245 -7.801  30.174  1.00 58.07  ? 388 GLU A OE2 1 
ATOM   3052  N N   . TYR A 1 389 ? -39.963 -10.422 23.783  1.00 44.24  ? 389 TYR A N   1 
ATOM   3053  C CA  . TYR A 1 389 ? -40.057 -11.282 22.616  1.00 43.18  ? 389 TYR A CA  1 
ATOM   3054  C C   . TYR A 1 389 ? -39.378 -12.632 22.812  1.00 43.99  ? 389 TYR A C   1 
ATOM   3055  O O   . TYR A 1 389 ? -39.927 -13.655 22.397  1.00 50.66  ? 389 TYR A O   1 
ATOM   3056  C CB  . TYR A 1 389 ? -39.395 -10.593 21.417  1.00 47.77  ? 389 TYR A CB  1 
ATOM   3057  C CG  . TYR A 1 389 ? -39.998 -9.256  21.020  1.00 57.21  ? 389 TYR A CG  1 
ATOM   3058  C CD1 . TYR A 1 389 ? -41.250 -9.172  20.413  1.00 55.76  ? 389 TYR A CD1 1 
ATOM   3059  C CD2 . TYR A 1 389 ? -39.335 -8.063  21.281  1.00 53.12  ? 389 TYR A CD2 1 
ATOM   3060  C CE1 . TYR A 1 389 ? -41.808 -7.954  20.057  1.00 57.17  ? 389 TYR A CE1 1 
ATOM   3061  C CE2 . TYR A 1 389 ? -39.887 -6.838  20.948  1.00 50.95  ? 389 TYR A CE2 1 
ATOM   3062  C CZ  . TYR A 1 389 ? -41.115 -6.784  20.311  1.00 57.75  ? 389 TYR A CZ  1 
ATOM   3063  O OH  . TYR A 1 389 ? -41.654 -5.565  19.943  1.00 67.14  ? 389 TYR A OH  1 
ATOM   3064  N N   . ASP A 1 390 ? -38.166 -12.625 23.389  1.00 44.01  ? 390 ASP A N   1 
ATOM   3065  C CA  . ASP A 1 390 ? -37.292 -13.797 23.400  1.00 49.19  ? 390 ASP A CA  1 
ATOM   3066  C C   . ASP A 1 390 ? -37.918 -14.936 24.211  1.00 44.30  ? 390 ASP A C   1 
ATOM   3067  O O   . ASP A 1 390 ? -37.703 -16.122 23.918  1.00 41.60  ? 390 ASP A O   1 
ATOM   3068  C CB  . ASP A 1 390 ? -35.906 -13.418 23.926  1.00 55.95  ? 390 ASP A CB  1 
ATOM   3069  C CG  . ASP A 1 390 ? -35.046 -12.603 22.974  1.00 60.92  ? 390 ASP A CG  1 
ATOM   3070  O OD1 . ASP A 1 390 ? -35.456 -12.412 21.826  1.00 73.50  ? 390 ASP A OD1 1 
ATOM   3071  O OD2 . ASP A 1 390 ? -33.967 -12.170 23.391  1.00 57.03  ? 390 ASP A OD2 1 
ATOM   3072  N N   . PHE A 1 391 ? -38.735 -14.527 25.190  1.00 36.73  ? 391 PHE A N   1 
ATOM   3073  C CA  . PHE A 1 391 ? -39.421 -15.403 26.107  1.00 34.35  ? 391 PHE A CA  1 
ATOM   3074  C C   . PHE A 1 391 ? -40.582 -16.155 25.453  1.00 36.31  ? 391 PHE A C   1 
ATOM   3075  O O   . PHE A 1 391 ? -41.079 -17.127 25.999  1.00 37.24  ? 391 PHE A O   1 
ATOM   3076  C CB  . PHE A 1 391 ? -39.932 -14.551 27.264  1.00 34.70  ? 391 PHE A CB  1 
ATOM   3077  C CG  . PHE A 1 391 ? -40.411 -15.372 28.423  1.00 36.08  ? 391 PHE A CG  1 
ATOM   3078  C CD1 . PHE A 1 391 ? -39.499 -16.041 29.226  1.00 36.65  ? 391 PHE A CD1 1 
ATOM   3079  C CD2 . PHE A 1 391 ? -41.761 -15.546 28.657  1.00 34.54  ? 391 PHE A CD2 1 
ATOM   3080  C CE1 . PHE A 1 391 ? -39.929 -16.873 30.251  1.00 34.56  ? 391 PHE A CE1 1 
ATOM   3081  C CE2 . PHE A 1 391 ? -42.183 -16.342 29.707  1.00 34.96  ? 391 PHE A CE2 1 
ATOM   3082  C CZ  . PHE A 1 391 ? -41.268 -17.003 30.501  1.00 34.47  ? 391 PHE A CZ  1 
ATOM   3083  N N   . TYR A 1 392 ? -41.060 -15.729 24.280  1.00 43.73  ? 392 TYR A N   1 
ATOM   3084  C CA  . TYR A 1 392 ? -42.225 -16.381 23.696  1.00 43.83  ? 392 TYR A CA  1 
ATOM   3085  C C   . TYR A 1 392 ? -41.933 -17.867 23.446  1.00 44.47  ? 392 TYR A C   1 
ATOM   3086  O O   . TYR A 1 392 ? -42.785 -18.745 23.546  1.00 43.20  ? 392 TYR A O   1 
ATOM   3087  C CB  . TYR A 1 392 ? -42.657 -15.645 22.425  1.00 44.46  ? 392 TYR A CB  1 
ATOM   3088  C CG  . TYR A 1 392 ? -43.259 -14.273 22.618  1.00 41.36  ? 392 TYR A CG  1 
ATOM   3089  C CD1 . TYR A 1 392 ? -43.630 -13.801 23.865  1.00 42.58  ? 392 TYR A CD1 1 
ATOM   3090  C CD2 . TYR A 1 392 ? -43.438 -13.429 21.539  1.00 42.85  ? 392 TYR A CD2 1 
ATOM   3091  C CE1 . TYR A 1 392 ? -44.185 -12.542 24.033  1.00 43.10  ? 392 TYR A CE1 1 
ATOM   3092  C CE2 . TYR A 1 392 ? -43.979 -12.159 21.693  1.00 45.70  ? 392 TYR A CE2 1 
ATOM   3093  C CZ  . TYR A 1 392 ? -44.380 -11.716 22.942  1.00 41.59  ? 392 TYR A CZ  1 
ATOM   3094  O OH  . TYR A 1 392 ? -44.895 -10.445 23.124  1.00 33.74  ? 392 TYR A OH  1 
ATOM   3095  N N   . THR A 1 393 ? -40.693 -18.144 23.097  1.00 44.88  ? 393 THR A N   1 
ATOM   3096  C CA  . THR A 1 393 ? -40.267 -19.493 22.774  1.00 47.40  ? 393 THR A CA  1 
ATOM   3097  C C   . THR A 1 393 ? -40.253 -20.353 24.034  1.00 39.55  ? 393 THR A C   1 
ATOM   3098  O O   . THR A 1 393 ? -40.542 -21.532 23.965  1.00 36.33  ? 393 THR A O   1 
ATOM   3099  C CB  . THR A 1 393 ? -38.909 -19.396 22.062  1.00 51.53  ? 393 THR A CB  1 
ATOM   3100  O OG1 . THR A 1 393 ? -39.086 -18.386 21.061  1.00 54.52  ? 393 THR A OG1 1 
ATOM   3101  C CG2 . THR A 1 393 ? -38.435 -20.700 21.464  1.00 47.28  ? 393 THR A CG2 1 
ATOM   3102  N N   . VAL A 1 394 ? -39.932 -19.764 25.184  1.00 36.63  ? 394 VAL A N   1 
ATOM   3103  C CA  . VAL A 1 394 ? -40.053 -20.483 26.438  1.00 36.03  ? 394 VAL A CA  1 
ATOM   3104  C C   . VAL A 1 394 ? -41.499 -20.928 26.684  1.00 35.23  ? 394 VAL A C   1 
ATOM   3105  O O   . VAL A 1 394 ? -41.709 -21.987 27.276  1.00 36.74  ? 394 VAL A O   1 
ATOM   3106  C CB  . VAL A 1 394 ? -39.552 -19.662 27.634  1.00 32.46  ? 394 VAL A CB  1 
ATOM   3107  C CG1 . VAL A 1 394 ? -39.769 -20.398 28.937  1.00 29.92  ? 394 VAL A CG1 1 
ATOM   3108  C CG2 . VAL A 1 394 ? -38.089 -19.291 27.466  1.00 37.38  ? 394 VAL A CG2 1 
ATOM   3109  N N   . LEU A 1 395 ? -42.497 -20.121 26.296  1.00 35.50  ? 395 LEU A N   1 
ATOM   3110  C CA  . LEU A 1 395 ? -43.901 -20.491 26.502  1.00 33.28  ? 395 LEU A CA  1 
ATOM   3111  C C   . LEU A 1 395 ? -44.252 -21.704 25.654  1.00 31.03  ? 395 LEU A C   1 
ATOM   3112  O O   . LEU A 1 395 ? -44.924 -22.643 26.107  1.00 26.30  ? 395 LEU A O   1 
ATOM   3113  C CB  . LEU A 1 395 ? -44.818 -19.335 26.093  1.00 33.84  ? 395 LEU A CB  1 
ATOM   3114  C CG  . LEU A 1 395 ? -44.684 -18.057 26.917  1.00 34.11  ? 395 LEU A CG  1 
ATOM   3115  C CD1 . LEU A 1 395 ? -45.428 -16.947 26.228  1.00 38.72  ? 395 LEU A CD1 1 
ATOM   3116  C CD2 . LEU A 1 395 ? -45.213 -18.229 28.325  1.00 33.49  ? 395 LEU A CD2 1 
ATOM   3117  N N   . PHE A 1 396 ? -43.818 -21.622 24.396  1.00 34.97  ? 396 PHE A N   1 
ATOM   3118  C CA  . PHE A 1 396 ? -43.925 -22.715 23.441  1.00 39.17  ? 396 PHE A CA  1 
ATOM   3119  C C   . PHE A 1 396 ? -43.376 -23.977 24.097  1.00 38.03  ? 396 PHE A C   1 
ATOM   3120  O O   . PHE A 1 396 ? -44.060 -24.989 24.138  1.00 45.51  ? 396 PHE A O   1 
ATOM   3121  C CB  . PHE A 1 396 ? -43.217 -22.290 22.151  1.00 42.85  ? 396 PHE A CB  1 
ATOM   3122  C CG  . PHE A 1 396 ? -43.481 -23.116 20.926  1.00 49.18  ? 396 PHE A CG  1 
ATOM   3123  C CD1 . PHE A 1 396 ? -43.885 -24.439 21.006  1.00 54.80  ? 396 PHE A CD1 1 
ATOM   3124  C CD2 . PHE A 1 396 ? -43.318 -22.555 19.673  1.00 59.32  ? 396 PHE A CD2 1 
ATOM   3125  C CE1 . PHE A 1 396 ? -44.125 -25.179 19.857  1.00 53.16  ? 396 PHE A CE1 1 
ATOM   3126  C CE2 . PHE A 1 396 ? -43.568 -23.297 18.527  1.00 66.50  ? 396 PHE A CE2 1 
ATOM   3127  C CZ  . PHE A 1 396 ? -43.971 -24.609 18.624  1.00 58.59  ? 396 PHE A CZ  1 
ATOM   3128  N N   . GLY A 1 397 ? -42.167 -23.874 24.660  1.00 36.57  ? 397 GLY A N   1 
ATOM   3129  C CA  . GLY A 1 397 ? -41.456 -24.978 25.302  1.00 35.88  ? 397 GLY A CA  1 
ATOM   3130  C C   . GLY A 1 397 ? -42.206 -25.632 26.467  1.00 32.68  ? 397 GLY A C   1 
ATOM   3131  O O   . GLY A 1 397 ? -42.122 -26.849 26.666  1.00 33.43  ? 397 GLY A O   1 
ATOM   3132  N N   . ILE A 1 398 ? -42.897 -24.827 27.278  1.00 28.49  ? 398 ILE A N   1 
ATOM   3133  C CA  . ILE A 1 398 ? -43.719 -25.362 28.360  1.00 29.16  ? 398 ILE A CA  1 
ATOM   3134  C C   . ILE A 1 398 ? -44.890 -26.152 27.751  1.00 32.10  ? 398 ILE A C   1 
ATOM   3135  O O   . ILE A 1 398 ? -45.149 -27.291 28.128  1.00 33.71  ? 398 ILE A O   1 
ATOM   3136  C CB  . ILE A 1 398 ? -44.179 -24.208 29.276  1.00 32.08  ? 398 ILE A CB  1 
ATOM   3137  C CG1 . ILE A 1 398 ? -42.992 -23.512 29.944  1.00 33.15  ? 398 ILE A CG1 1 
ATOM   3138  C CG2 . ILE A 1 398 ? -45.188 -24.669 30.306  1.00 34.10  ? 398 ILE A CG2 1 
ATOM   3139  C CD1 . ILE A 1 398 ? -43.302 -22.151 30.475  1.00 34.04  ? 398 ILE A CD1 1 
ATOM   3140  N N   . GLY A 1 399 ? -45.567 -25.571 26.744  1.00 34.67  ? 399 GLY A N   1 
ATOM   3141  C CA  . GLY A 1 399 ? -46.720 -26.205 26.110  1.00 31.30  ? 399 GLY A CA  1 
ATOM   3142  C C   . GLY A 1 399 ? -46.373 -27.524 25.431  1.00 29.49  ? 399 GLY A C   1 
ATOM   3143  O O   . GLY A 1 399 ? -46.983 -28.540 25.717  1.00 29.45  ? 399 GLY A O   1 
ATOM   3144  N N   . ARG A 1 400 ? -45.367 -27.490 24.547  1.00 31.96  ? 400 ARG A N   1 
ATOM   3145  C CA  . ARG A 1 400 ? -44.888 -28.639 23.791  1.00 30.52  ? 400 ARG A CA  1 
ATOM   3146  C C   . ARG A 1 400 ? -44.465 -29.814 24.682  1.00 31.22  ? 400 ARG A C   1 
ATOM   3147  O O   . ARG A 1 400 ? -44.435 -30.969 24.247  1.00 31.52  ? 400 ARG A O   1 
ATOM   3148  C CB  . ARG A 1 400 ? -43.733 -28.139 22.919  1.00 33.25  ? 400 ARG A CB  1 
ATOM   3149  C CG  . ARG A 1 400 ? -43.139 -29.159 21.958  1.00 37.77  ? 400 ARG A CG  1 
ATOM   3150  C CD  . ARG A 1 400 ? -44.193 -30.018 21.253  1.00 40.27  ? 400 ARG A CD  1 
ATOM   3151  N NE  . ARG A 1 400 ? -45.236 -29.276 20.547  1.00 37.58  ? 400 ARG A NE  1 
ATOM   3152  C CZ  . ARG A 1 400 ? -45.081 -28.757 19.335  1.00 39.74  ? 400 ARG A CZ  1 
ATOM   3153  N NH1 . ARG A 1 400 ? -43.969 -29.019 18.637  1.00 37.87  ? 400 ARG A NH1 1 
ATOM   3154  N NH2 . ARG A 1 400 ? -46.048 -27.989 18.836  1.00 36.88  ? 400 ARG A NH2 1 
ATOM   3155  N N   . ALA A 1 401 ? -44.162 -29.570 25.959  1.00 31.59  ? 401 ALA A N   1 
ATOM   3156  C CA  . ALA A 1 401 ? -43.723 -30.673 26.810  1.00 33.30  ? 401 ALA A CA  1 
ATOM   3157  C C   . ALA A 1 401 ? -44.856 -31.675 27.022  1.00 33.96  ? 401 ALA A C   1 
ATOM   3158  O O   . ALA A 1 401 ? -44.587 -32.848 27.255  1.00 35.31  ? 401 ALA A O   1 
ATOM   3159  C CB  . ALA A 1 401 ? -43.174 -30.159 28.121  1.00 29.18  ? 401 ALA A CB  1 
ATOM   3160  N N   . LEU A 1 402 ? -46.107 -31.192 26.985  1.00 33.17  ? 402 LEU A N   1 
ATOM   3161  C CA  . LEU A 1 402 ? -47.269 -32.031 27.279  1.00 36.64  ? 402 LEU A CA  1 
ATOM   3162  C C   . LEU A 1 402 ? -47.292 -33.205 26.300  1.00 35.44  ? 402 LEU A C   1 
ATOM   3163  O O   . LEU A 1 402 ? -47.390 -34.363 26.683  1.00 38.83  ? 402 LEU A O   1 
ATOM   3164  C CB  . LEU A 1 402 ? -48.556 -31.209 27.135  1.00 37.05  ? 402 LEU A CB  1 
ATOM   3165  C CG  . LEU A 1 402 ? -48.775 -30.073 28.141  1.00 38.42  ? 402 LEU A CG  1 
ATOM   3166  C CD1 . LEU A 1 402 ? -49.839 -29.086 27.666  1.00 38.23  ? 402 LEU A CD1 1 
ATOM   3167  C CD2 . LEU A 1 402 ? -49.174 -30.609 29.501  1.00 43.09  ? 402 LEU A CD2 1 
ATOM   3168  N N   . GLY A 1 403 ? -47.133 -32.875 25.023  1.00 37.42  ? 403 GLY A N   1 
ATOM   3169  C CA  . GLY A 1 403 ? -47.150 -33.859 23.970  1.00 36.87  ? 403 GLY A CA  1 
ATOM   3170  C C   . GLY A 1 403 ? -45.886 -34.697 23.980  1.00 33.69  ? 403 GLY A C   1 
ATOM   3171  O O   . GLY A 1 403 ? -45.945 -35.917 23.836  1.00 34.12  ? 403 GLY A O   1 
ATOM   3172  N N   . VAL A 1 404 ? -44.744 -34.034 24.114  1.00 34.31  ? 404 VAL A N   1 
ATOM   3173  C CA  . VAL A 1 404 ? -43.467 -34.699 23.904  1.00 33.65  ? 404 VAL A CA  1 
ATOM   3174  C C   . VAL A 1 404 ? -43.230 -35.699 25.021  1.00 35.55  ? 404 VAL A C   1 
ATOM   3175  O O   . VAL A 1 404 ? -42.820 -36.817 24.722  1.00 44.42  ? 404 VAL A O   1 
ATOM   3176  C CB  . VAL A 1 404 ? -42.309 -33.695 23.805  1.00 35.55  ? 404 VAL A CB  1 
ATOM   3177  C CG1 . VAL A 1 404 ? -40.958 -34.377 23.921  1.00 36.51  ? 404 VAL A CG1 1 
ATOM   3178  C CG2 . VAL A 1 404 ? -42.404 -32.893 22.516  1.00 35.64  ? 404 VAL A CG2 1 
ATOM   3179  N N   . LEU A 1 405 ? -43.506 -35.305 26.276  1.00 37.11  ? 405 LEU A N   1 
ATOM   3180  C CA  . LEU A 1 405 ? -43.254 -36.174 27.423  1.00 39.65  ? 405 LEU A CA  1 
ATOM   3181  C C   . LEU A 1 405 ? -44.187 -37.391 27.378  1.00 39.77  ? 405 LEU A C   1 
ATOM   3182  O O   . LEU A 1 405 ? -43.756 -38.502 27.672  1.00 43.08  ? 405 LEU A O   1 
ATOM   3183  C CB  . LEU A 1 405 ? -43.384 -35.393 28.741  1.00 43.25  ? 405 LEU A CB  1 
ATOM   3184  C CG  . LEU A 1 405 ? -42.374 -34.255 28.965  1.00 48.39  ? 405 LEU A CG  1 
ATOM   3185  C CD1 . LEU A 1 405 ? -42.610 -33.545 30.303  1.00 52.91  ? 405 LEU A CD1 1 
ATOM   3186  C CD2 . LEU A 1 405 ? -40.944 -34.759 28.898  1.00 50.84  ? 405 LEU A CD2 1 
ATOM   3187  N N   . ALA A 1 406 ? -45.456 -37.186 26.997  1.00 40.08  ? 406 ALA A N   1 
ATOM   3188  C CA  . ALA A 1 406 ? -46.403 -38.277 26.766  1.00 35.30  ? 406 ALA A CA  1 
ATOM   3189  C C   . ALA A 1 406 ? -45.893 -39.201 25.669  1.00 34.25  ? 406 ALA A C   1 
ATOM   3190  O O   . ALA A 1 406 ? -45.917 -40.414 25.816  1.00 39.52  ? 406 ALA A O   1 
ATOM   3191  C CB  . ALA A 1 406 ? -47.754 -37.711 26.401  1.00 36.37  ? 406 ALA A CB  1 
ATOM   3192  N N   . ASN A 1 407 ? -45.380 -38.627 24.583  1.00 34.30  ? 407 ASN A N   1 
ATOM   3193  C CA  . ASN A 1 407 ? -44.823 -39.428 23.513  1.00 35.55  ? 407 ASN A CA  1 
ATOM   3194  C C   . ASN A 1 407 ? -43.646 -40.250 24.024  1.00 33.09  ? 407 ASN A C   1 
ATOM   3195  O O   . ASN A 1 407 ? -43.520 -41.392 23.649  1.00 34.34  ? 407 ASN A O   1 
ATOM   3196  C CB  . ASN A 1 407 ? -44.456 -38.594 22.284  1.00 39.90  ? 407 ASN A CB  1 
ATOM   3197  C CG  . ASN A 1 407 ? -44.359 -39.438 21.025  1.00 50.71  ? 407 ASN A CG  1 
ATOM   3198  O OD1 . ASN A 1 407 ? -43.361 -39.375 20.302  1.00 62.40  ? 407 ASN A OD1 1 
ATOM   3199  N ND2 . ASN A 1 407 ? -45.385 -40.241 20.754  1.00 48.64  ? 407 ASN A ND2 1 
ATOM   3200  N N   . LEU A 1 408 ? -42.804 -39.728 24.916  1.00 40.81  ? 408 LEU A N   1 
ATOM   3201  C CA  . LEU A 1 408 ? -41.640 -40.474 25.389  1.00 39.61  ? 408 LEU A CA  1 
ATOM   3202  C C   . LEU A 1 408 ? -42.046 -41.657 26.254  1.00 38.45  ? 408 LEU A C   1 
ATOM   3203  O O   . LEU A 1 408 ? -41.333 -42.657 26.294  1.00 44.00  ? 408 LEU A O   1 
ATOM   3204  C CB  . LEU A 1 408 ? -40.719 -39.574 26.218  1.00 41.55  ? 408 LEU A CB  1 
ATOM   3205  C CG  . LEU A 1 408 ? -40.045 -38.412 25.480  1.00 49.17  ? 408 LEU A CG  1 
ATOM   3206  C CD1 . LEU A 1 408 ? -38.803 -37.996 26.255  1.00 53.25  ? 408 LEU A CD1 1 
ATOM   3207  C CD2 . LEU A 1 408 ? -39.703 -38.723 24.005  1.00 51.42  ? 408 LEU A CD2 1 
ATOM   3208  N N   . VAL A 1 409 ? -43.146 -41.520 26.997  1.00 37.09  ? 409 VAL A N   1 
ATOM   3209  C CA  . VAL A 1 409 ? -43.633 -42.616 27.824  1.00 38.19  ? 409 VAL A CA  1 
ATOM   3210  C C   . VAL A 1 409 ? -44.043 -43.785 26.926  1.00 36.91  ? 409 VAL A C   1 
ATOM   3211  O O   . VAL A 1 409 ? -43.656 -44.915 27.174  1.00 31.61  ? 409 VAL A O   1 
ATOM   3212  C CB  . VAL A 1 409 ? -44.814 -42.163 28.706  1.00 38.25  ? 409 VAL A CB  1 
ATOM   3213  C CG1 . VAL A 1 409 ? -45.495 -43.346 29.399  1.00 38.09  ? 409 VAL A CG1 1 
ATOM   3214  C CG2 . VAL A 1 409 ? -44.380 -41.106 29.710  1.00 35.87  ? 409 VAL A CG2 1 
ATOM   3215  N N   . TRP A 1 410 ? -44.830 -43.486 25.886  1.00 36.04  ? 410 TRP A N   1 
ATOM   3216  C CA  . TRP A 1 410 ? -45.289 -44.481 24.941  1.00 40.52  ? 410 TRP A CA  1 
ATOM   3217  C C   . TRP A 1 410 ? -44.116 -45.116 24.189  1.00 43.61  ? 410 TRP A C   1 
ATOM   3218  O O   . TRP A 1 410 ? -44.077 -46.331 24.036  1.00 44.08  ? 410 TRP A O   1 
ATOM   3219  C CB  . TRP A 1 410 ? -46.366 -43.873 24.024  1.00 42.17  ? 410 TRP A CB  1 
ATOM   3220  C CG  . TRP A 1 410 ? -47.703 -43.871 24.714  1.00 48.25  ? 410 TRP A CG  1 
ATOM   3221  C CD1 . TRP A 1 410 ? -48.287 -42.854 25.423  1.00 53.05  ? 410 TRP A CD1 1 
ATOM   3222  C CD2 . TRP A 1 410 ? -48.596 -44.993 24.838  1.00 50.12  ? 410 TRP A CD2 1 
ATOM   3223  N NE1 . TRP A 1 410 ? -49.473 -43.260 25.968  1.00 47.57  ? 410 TRP A NE1 1 
ATOM   3224  C CE2 . TRP A 1 410 ? -49.691 -44.569 25.628  1.00 52.12  ? 410 TRP A CE2 1 
ATOM   3225  C CE3 . TRP A 1 410 ? -48.581 -46.306 24.350  1.00 52.10  ? 410 TRP A CE3 1 
ATOM   3226  C CZ2 . TRP A 1 410 ? -50.761 -45.417 25.932  1.00 53.06  ? 410 TRP A CZ2 1 
ATOM   3227  C CZ3 . TRP A 1 410 ? -49.623 -47.147 24.673  1.00 54.30  ? 410 TRP A CZ3 1 
ATOM   3228  C CH2 . TRP A 1 410 ? -50.705 -46.703 25.436  1.00 57.19  ? 410 TRP A CH2 1 
ATOM   3229  N N   . ASP A 1 411 ? -43.111 -44.336 23.785  1.00 41.67  ? 411 ASP A N   1 
ATOM   3230  C CA  . ASP A 1 411 ? -41.968 -44.885 23.078  1.00 42.22  ? 411 ASP A CA  1 
ATOM   3231  C C   . ASP A 1 411 ? -41.324 -45.994 23.906  1.00 40.69  ? 411 ASP A C   1 
ATOM   3232  O O   . ASP A 1 411 ? -40.871 -47.001 23.356  1.00 39.24  ? 411 ASP A O   1 
ATOM   3233  C CB  . ASP A 1 411 ? -40.956 -43.785 22.745  1.00 53.60  ? 411 ASP A CB  1 
ATOM   3234  C CG  . ASP A 1 411 ? -41.371 -42.787 21.657  1.00 67.39  ? 411 ASP A CG  1 
ATOM   3235  O OD1 . ASP A 1 411 ? -42.342 -43.089 20.905  1.00 77.75  ? 411 ASP A OD1 1 
ATOM   3236  O OD2 . ASP A 1 411 ? -40.744 -41.667 21.581  1.00 70.53  ? 411 ASP A OD2 1 
ATOM   3237  N N   . ARG A 1 412 ? -41.265 -45.797 25.225  1.00 38.82  ? 412 ARG A N   1 
ATOM   3238  C CA  . ARG A 1 412 ? -40.657 -46.775 26.122  1.00 46.41  ? 412 ARG A CA  1 
ATOM   3239  C C   . ARG A 1 412 ? -41.628 -47.918 26.403  1.00 49.36  ? 412 ARG A C   1 
ATOM   3240  O O   . ARG A 1 412 ? -41.218 -49.073 26.512  1.00 49.32  ? 412 ARG A O   1 
ATOM   3241  C CB  . ARG A 1 412 ? -40.233 -46.146 27.453  1.00 42.61  ? 412 ARG A CB  1 
ATOM   3242  C CG  . ARG A 1 412 ? -39.048 -45.200 27.344  1.00 42.52  ? 412 ARG A CG  1 
ATOM   3243  C CD  . ARG A 1 412 ? -37.726 -45.880 27.035  1.00 46.15  ? 412 ARG A CD  1 
ATOM   3244  N NE  . ARG A 1 412 ? -37.552 -46.315 25.650  1.00 49.95  ? 412 ARG A NE  1 
ATOM   3245  C CZ  . ARG A 1 412 ? -37.642 -45.530 24.581  1.00 58.70  ? 412 ARG A CZ  1 
ATOM   3246  N NH1 . ARG A 1 412 ? -37.610 -46.050 23.361  1.00 61.29  ? 412 ARG A NH1 1 
ATOM   3247  N NH2 . ARG A 1 412 ? -37.791 -44.224 24.741  1.00 70.69  ? 412 ARG A NH2 1 
ATOM   3248  N N   . ALA A 1 413 ? -42.912 -47.565 26.513  1.00 51.32  ? 413 ALA A N   1 
ATOM   3249  C CA  . ALA A 1 413 ? -43.986 -48.523 26.703  1.00 45.07  ? 413 ALA A CA  1 
ATOM   3250  C C   . ALA A 1 413 ? -43.934 -49.562 25.591  1.00 42.01  ? 413 ALA A C   1 
ATOM   3251  O O   . ALA A 1 413 ? -43.884 -50.746 25.870  1.00 46.69  ? 413 ALA A O   1 
ATOM   3252  C CB  . ALA A 1 413 ? -45.319 -47.803 26.747  1.00 43.41  ? 413 ALA A CB  1 
ATOM   3253  N N   . LEU A 1 414 ? -43.866 -49.101 24.336  1.00 44.98  ? 414 LEU A N   1 
ATOM   3254  C CA  . LEU A 1 414 ? -43.937 -49.976 23.165  1.00 43.69  ? 414 LEU A CA  1 
ATOM   3255  C C   . LEU A 1 414 ? -42.546 -50.462 22.745  1.00 44.96  ? 414 LEU A C   1 
ATOM   3256  O O   . LEU A 1 414 ? -42.427 -51.120 21.713  1.00 48.37  ? 414 LEU A O   1 
ATOM   3257  C CB  . LEU A 1 414 ? -44.606 -49.232 21.997  1.00 40.48  ? 414 LEU A CB  1 
ATOM   3258  C CG  . LEU A 1 414 ? -45.962 -48.591 22.310  1.00 43.23  ? 414 LEU A CG  1 
ATOM   3259  C CD1 . LEU A 1 414 ? -46.494 -47.839 21.098  1.00 39.26  ? 414 LEU A CD1 1 
ATOM   3260  C CD2 . LEU A 1 414 ? -46.960 -49.638 22.826  1.00 43.28  ? 414 LEU A CD2 1 
ATOM   3261  N N   . GLY A 1 415 ? -41.499 -50.077 23.491  1.00 49.39  ? 415 GLY A N   1 
ATOM   3262  C CA  . GLY A 1 415 ? -40.154 -50.599 23.311  1.00 48.12  ? 415 GLY A CA  1 
ATOM   3263  C C   . GLY A 1 415 ? -39.502 -50.172 21.991  1.00 51.86  ? 415 GLY A C   1 
ATOM   3264  O O   . GLY A 1 415 ? -38.659 -50.910 21.479  1.00 53.52  ? 415 GLY A O   1 
ATOM   3265  N N   . TYR A 1 416 ? -39.850 -48.986 21.454  1.00 48.57  ? 416 TYR A N   1 
ATOM   3266  C CA  . TYR A 1 416 ? -39.329 -48.568 20.152  1.00 49.40  ? 416 TYR A CA  1 
ATOM   3267  C C   . TYR A 1 416 ? -37.807 -48.464 20.182  1.00 48.16  ? 416 TYR A C   1 
ATOM   3268  O O   . TYR A 1 416 ? -37.229 -48.036 21.170  1.00 59.19  ? 416 TYR A O   1 
ATOM   3269  C CB  . TYR A 1 416 ? -39.900 -47.228 19.688  1.00 47.50  ? 416 TYR A CB  1 
ATOM   3270  C CG  . TYR A 1 416 ? -41.350 -47.232 19.270  1.00 51.88  ? 416 TYR A CG  1 
ATOM   3271  C CD1 . TYR A 1 416 ? -42.020 -48.377 18.864  1.00 51.01  ? 416 TYR A CD1 1 
ATOM   3272  C CD2 . TYR A 1 416 ? -42.067 -46.052 19.296  1.00 56.32  ? 416 TYR A CD2 1 
ATOM   3273  C CE1 . TYR A 1 416 ? -43.358 -48.330 18.501  1.00 55.07  ? 416 TYR A CE1 1 
ATOM   3274  C CE2 . TYR A 1 416 ? -43.403 -45.988 18.938  1.00 61.77  ? 416 TYR A CE2 1 
ATOM   3275  C CZ  . TYR A 1 416 ? -44.055 -47.130 18.518  1.00 59.26  ? 416 TYR A CZ  1 
ATOM   3276  O OH  . TYR A 1 416 ? -45.387 -47.006 18.152  1.00 61.53  ? 416 TYR A OH  1 
ATOM   3277  N N   . ALA A 1 417 ? -37.168 -48.848 19.074  1.00 52.77  ? 417 ALA A N   1 
ATOM   3278  C CA  . ALA A 1 417 ? -35.727 -49.043 19.055  1.00 53.02  ? 417 ALA A CA  1 
ATOM   3279  C C   . ALA A 1 417 ? -35.039 -47.729 18.729  1.00 50.85  ? 417 ALA A C   1 
ATOM   3280  O O   . ALA A 1 417 ? -35.666 -46.766 18.291  1.00 54.14  ? 417 ALA A O   1 
ATOM   3281  C CB  . ALA A 1 417 ? -35.325 -50.100 18.056  1.00 52.97  ? 417 ALA A CB  1 
ATOM   3282  N N   . ILE A 1 418 ? -33.729 -47.752 18.937  1.00 50.04  ? 418 ILE A N   1 
ATOM   3283  C CA  . ILE A 1 418 ? -32.851 -46.631 18.664  1.00 53.52  ? 418 ILE A CA  1 
ATOM   3284  C C   . ILE A 1 418 ? -33.003 -46.191 17.204  1.00 54.33  ? 418 ILE A C   1 
ATOM   3285  O O   . ILE A 1 418 ? -33.111 -47.023 16.301  1.00 54.78  ? 418 ILE A O   1 
ATOM   3286  C CB  . ILE A 1 418 ? -31.418 -47.030 19.067  1.00 53.86  ? 418 ILE A CB  1 
ATOM   3287  C CG1 . ILE A 1 418 ? -30.451 -45.847 19.054  1.00 51.55  ? 418 ILE A CG1 1 
ATOM   3288  C CG2 . ILE A 1 418 ? -30.906 -48.211 18.246  1.00 54.69  ? 418 ILE A CG2 1 
ATOM   3289  C CD1 . ILE A 1 418 ? -29.121 -46.178 19.719  1.00 49.74  ? 418 ILE A CD1 1 
ATOM   3290  N N   . GLU A 1 419 ? -33.073 -44.862 17.004  1.00 53.32  ? 419 GLU A N   1 
ATOM   3291  C CA  . GLU A 1 419 ? -33.193 -44.279 15.681  1.00 49.66  ? 419 GLU A CA  1 
ATOM   3292  C C   . GLU A 1 419 ? -31.795 -44.167 15.075  1.00 47.13  ? 419 GLU A C   1 
ATOM   3293  O O   . GLU A 1 419 ? -30.964 -43.407 15.560  1.00 55.61  ? 419 GLU A O   1 
ATOM   3294  C CB  . GLU A 1 419 ? -33.911 -42.935 15.788  1.00 58.80  ? 419 GLU A CB  1 
ATOM   3295  C CG  . GLU A 1 419 ? -34.185 -42.260 14.435  1.00 66.12  ? 419 GLU A CG  1 
ATOM   3296  C CD  . GLU A 1 419 ? -35.151 -41.078 14.491  1.00 69.00  ? 419 GLU A CD  1 
ATOM   3297  O OE1 . GLU A 1 419 ? -36.232 -41.215 15.152  1.00 69.86  ? 419 GLU A OE1 1 
ATOM   3298  O OE2 . GLU A 1 419 ? -34.836 -40.027 13.869  1.00 58.74  ? 419 GLU A OE2 1 
ATOM   3299  N N   . ARG A 1 420 ? -31.535 -44.964 14.037  1.00 43.78  ? 420 ARG A N   1 
ATOM   3300  C CA  . ARG A 1 420 ? -30.228 -45.083 13.413  1.00 47.46  ? 420 ARG A CA  1 
ATOM   3301  C C   . ARG A 1 420 ? -30.473 -45.265 11.917  1.00 51.10  ? 420 ARG A C   1 
ATOM   3302  O O   . ARG A 1 420 ? -30.467 -46.388 11.425  1.00 55.08  ? 420 ARG A O   1 
ATOM   3303  C CB  . ARG A 1 420 ? -29.444 -46.251 14.028  1.00 51.66  ? 420 ARG A CB  1 
ATOM   3304  C CG  . ARG A 1 420 ? -27.924 -46.165 13.917  1.00 57.39  ? 420 ARG A CG  1 
ATOM   3305  C CD  . ARG A 1 420 ? -27.359 -45.800 12.544  1.00 63.38  ? 420 ARG A CD  1 
ATOM   3306  N NE  . ARG A 1 420 ? -25.892 -45.721 12.515  1.00 68.84  ? 420 ARG A NE  1 
ATOM   3307  C CZ  . ARG A 1 420 ? -25.154 -45.077 11.593  1.00 70.37  ? 420 ARG A CZ  1 
ATOM   3308  N NH1 . ARG A 1 420 ? -25.709 -44.545 10.513  1.00 56.01  ? 420 ARG A NH1 1 
ATOM   3309  N NH2 . ARG A 1 420 ? -23.843 -44.961 11.758  1.00 66.89  ? 420 ARG A NH2 1 
ATOM   3310  N N   . PRO A 1 421 ? -30.791 -44.184 11.160  1.00 50.78  ? 421 PRO A N   1 
ATOM   3311  C CA  . PRO A 1 421 ? -30.883 -44.264 9.706   1.00 51.24  ? 421 PRO A CA  1 
ATOM   3312  C C   . PRO A 1 421 ? -29.485 -44.332 9.115   1.00 53.13  ? 421 PRO A C   1 
ATOM   3313  O O   . PRO A 1 421 ? -28.516 -44.247 9.850   1.00 60.73  ? 421 PRO A O   1 
ATOM   3314  C CB  . PRO A 1 421 ? -31.616 -42.979 9.305   1.00 52.25  ? 421 PRO A CB  1 
ATOM   3315  C CG  . PRO A 1 421 ? -31.268 -42.010 10.403  1.00 51.51  ? 421 PRO A CG  1 
ATOM   3316  C CD  . PRO A 1 421 ? -31.127 -42.843 11.654  1.00 49.62  ? 421 PRO A CD  1 
ATOM   3317  N N   . LYS A 1 422 ? -29.397 -44.473 7.790   1.00 58.33  ? 422 LYS A N   1 
ATOM   3318  C CA  . LYS A 1 422 ? -28.127 -44.633 7.099   1.00 64.42  ? 422 LYS A CA  1 
ATOM   3319  C C   . LYS A 1 422 ? -27.815 -43.350 6.336   1.00 59.70  ? 422 LYS A C   1 
ATOM   3320  O O   . LYS A 1 422 ? -28.725 -42.710 5.806   1.00 56.62  ? 422 LYS A O   1 
ATOM   3321  C CB  . LYS A 1 422 ? -28.200 -45.845 6.159   1.00 74.52  ? 422 LYS A CB  1 
ATOM   3322  C CG  . LYS A 1 422 ? -26.872 -46.315 5.580   1.00 77.36  ? 422 LYS A CG  1 
ATOM   3323  C CD  . LYS A 1 422 ? -25.919 -46.917 6.610   1.00 81.02  ? 422 LYS A CD  1 
ATOM   3324  C CE  . LYS A 1 422 ? -24.664 -47.514 5.996   1.00 91.82  ? 422 LYS A CE  1 
ATOM   3325  N NZ  . LYS A 1 422 ? -23.650 -46.499 5.601   1.00 93.94  ? 422 LYS A NZ  1 
ATOM   3326  N N   . SER A 1 423 ? -26.524 -42.987 6.292   1.00 57.38  ? 423 SER A N   1 
ATOM   3327  C CA  . SER A 1 423 ? -26.060 -41.831 5.539   1.00 61.45  ? 423 SER A CA  1 
ATOM   3328  C C   . SER A 1 423 ? -25.474 -42.267 4.197   1.00 58.78  ? 423 SER A C   1 
ATOM   3329  O O   . SER A 1 423 ? -24.979 -43.380 4.031   1.00 49.61  ? 423 SER A O   1 
ATOM   3330  C CB  . SER A 1 423 ? -25.023 -41.047 6.311   1.00 65.80  ? 423 SER A CB  1 
ATOM   3331  O OG  . SER A 1 423 ? -25.399 -40.908 7.670   1.00 70.39  ? 423 SER A OG  1 
ATOM   3332  N N   . VAL A 1 424 ? -25.470 -41.329 3.259   1.00 63.07  ? 424 VAL A N   1 
ATOM   3333  C CA  . VAL A 1 424 ? -24.872 -41.546 1.955   1.00 66.09  ? 424 VAL A CA  1 
ATOM   3334  C C   . VAL A 1 424 ? -24.134 -40.272 1.560   1.00 66.28  ? 424 VAL A C   1 
ATOM   3335  O O   . VAL A 1 424 ? -24.441 -39.181 2.052   1.00 56.77  ? 424 VAL A O   1 
ATOM   3336  C CB  . VAL A 1 424 ? -25.946 -41.928 0.920   1.00 69.16  ? 424 VAL A CB  1 
ATOM   3337  C CG1 . VAL A 1 424 ? -26.747 -43.133 1.403   1.00 73.43  ? 424 VAL A CG1 1 
ATOM   3338  C CG2 . VAL A 1 424 ? -26.874 -40.761 0.565   1.00 59.96  ? 424 VAL A CG2 1 
ATOM   3339  N N   . THR A 1 425 ? -23.153 -40.433 0.673   1.00 62.71  ? 425 THR A N   1 
ATOM   3340  C CA  . THR A 1 425 ? -22.345 -39.315 0.228   1.00 58.78  ? 425 THR A CA  1 
ATOM   3341  C C   . THR A 1 425 ? -22.987 -38.716 -1.011  1.00 57.33  ? 425 THR A C   1 
ATOM   3342  O O   . THR A 1 425 ? -23.945 -39.261 -1.555  1.00 59.39  ? 425 THR A O   1 
ATOM   3343  C CB  . THR A 1 425 ? -20.903 -39.757 -0.013  1.00 63.43  ? 425 THR A CB  1 
ATOM   3344  O OG1 . THR A 1 425 ? -20.879 -40.539 -1.201  1.00 72.04  ? 425 THR A OG1 1 
ATOM   3345  C CG2 . THR A 1 425 ? -20.338 -40.584 1.126   1.00 60.58  ? 425 THR A CG2 1 
ATOM   3346  N N   . THR A 1 426 ? -22.468 -37.557 -1.412  1.00 63.05  ? 426 THR A N   1 
ATOM   3347  C CA  . THR A 1 426 ? -22.822 -36.958 -2.681  1.00 64.33  ? 426 THR A CA  1 
ATOM   3348  C C   . THR A 1 426 ? -22.255 -37.805 -3.819  1.00 61.88  ? 426 THR A C   1 
ATOM   3349  O O   . THR A 1 426 ? -22.946 -37.968 -4.818  1.00 61.21  ? 426 THR A O   1 
ATOM   3350  C CB  . THR A 1 426 ? -22.363 -35.503 -2.698  1.00 69.99  ? 426 THR A CB  1 
ATOM   3351  O OG1 . THR A 1 426 ? -23.070 -34.916 -1.609  1.00 64.94  ? 426 THR A OG1 1 
ATOM   3352  C CG2 . THR A 1 426 ? -22.673 -34.757 -3.977  1.00 76.64  ? 426 THR A CG2 1 
ATOM   3353  N N   . ASP A 1 427 ? -21.046 -38.363 -3.638  1.00 57.63  ? 427 ASP A N   1 
ATOM   3354  C CA  . ASP A 1 427 ? -20.467 -39.313 -4.585  1.00 72.46  ? 427 ASP A CA  1 
ATOM   3355  C C   . ASP A 1 427 ? -21.423 -40.472 -4.882  1.00 76.36  ? 427 ASP A C   1 
ATOM   3356  O O   . ASP A 1 427 ? -21.589 -40.849 -6.036  1.00 90.88  ? 427 ASP A O   1 
ATOM   3357  C CB  . ASP A 1 427 ? -19.131 -39.891 -4.089  1.00 75.93  ? 427 ASP A CB  1 
ATOM   3358  C CG  . ASP A 1 427 ? -17.938 -38.994 -4.355  1.00 83.16  ? 427 ASP A CG  1 
ATOM   3359  O OD1 . ASP A 1 427 ? -18.147 -37.772 -4.449  1.00 94.75  ? 427 ASP A OD1 1 
ATOM   3360  O OD2 . ASP A 1 427 ? -16.825 -39.533 -4.531  1.00 79.33  ? 427 ASP A OD2 1 
ATOM   3361  N N   . MET A 1 428 ? -22.015 -41.045 -3.830  1.00 72.32  ? 428 MET A N   1 
ATOM   3362  C CA  . MET A 1 428 ? -22.951 -42.148 -3.943  1.00 63.72  ? 428 MET A CA  1 
ATOM   3363  C C   . MET A 1 428 ? -24.232 -41.694 -4.645  1.00 68.24  ? 428 MET A C   1 
ATOM   3364  O O   . MET A 1 428 ? -24.738 -42.410 -5.494  1.00 75.19  ? 428 MET A O   1 
ATOM   3365  C CB  . MET A 1 428 ? -23.284 -42.709 -2.557  1.00 62.67  ? 428 MET A CB  1 
ATOM   3366  C CG  . MET A 1 428 ? -22.207 -43.633 -2.027  1.00 68.23  ? 428 MET A CG  1 
ATOM   3367  S SD  . MET A 1 428 ? -22.352 -44.014 -0.252  1.00 77.73  ? 428 MET A SD  1 
ATOM   3368  C CE  . MET A 1 428 ? -23.767 -45.113 -0.258  1.00 81.09  ? 428 MET A CE  1 
ATOM   3369  N N   . LEU A 1 429 ? -24.767 -40.516 -4.313  1.00 67.84  ? 429 LEU A N   1 
ATOM   3370  C CA  . LEU A 1 429 ? -25.964 -40.014 -4.985  1.00 72.24  ? 429 LEU A CA  1 
ATOM   3371  C C   . LEU A 1 429 ? -25.701 -39.744 -6.463  1.00 74.68  ? 429 LEU A C   1 
ATOM   3372  O O   . LEU A 1 429 ? -26.629 -39.724 -7.274  1.00 73.32  ? 429 LEU A O   1 
ATOM   3373  C CB  . LEU A 1 429 ? -26.417 -38.720 -4.309  1.00 77.87  ? 429 LEU A CB  1 
ATOM   3374  C CG  . LEU A 1 429 ? -27.067 -38.887 -2.932  1.00 85.17  ? 429 LEU A CG  1 
ATOM   3375  C CD1 . LEU A 1 429 ? -27.460 -37.531 -2.354  1.00 89.38  ? 429 LEU A CD1 1 
ATOM   3376  C CD2 . LEU A 1 429 ? -28.279 -39.820 -2.994  1.00 82.20  ? 429 LEU A CD2 1 
ATOM   3377  N N   . GLU A 1 430 ? -24.437 -39.445 -6.773  1.00 82.23  ? 430 GLU A N   1 
ATOM   3378  C CA  . GLU A 1 430 ? -24.010 -39.115 -8.120  1.00 82.96  ? 430 GLU A CA  1 
ATOM   3379  C C   . GLU A 1 430 ? -23.855 -40.392 -8.943  1.00 74.19  ? 430 GLU A C   1 
ATOM   3380  O O   . GLU A 1 430 ? -24.210 -40.398 -10.110 1.00 71.62  ? 430 GLU A O   1 
ATOM   3381  C CB  . GLU A 1 430 ? -22.725 -38.284 -8.072  1.00 86.99  ? 430 GLU A CB  1 
ATOM   3382  C CG  . GLU A 1 430 ? -22.996 -36.800 -7.874  1.00 83.43  ? 430 GLU A CG  1 
ATOM   3383  C CD  . GLU A 1 430 ? -21.772 -35.898 -7.819  1.00 80.85  ? 430 GLU A CD  1 
ATOM   3384  O OE1 . GLU A 1 430 ? -20.644 -36.412 -7.541  1.00 66.38  ? 430 GLU A OE1 1 
ATOM   3385  O OE2 . GLU A 1 430 ? -21.955 -34.673 -8.043  1.00 75.12  ? 430 GLU A OE2 1 
ATOM   3386  N N   . LYS A 1 431 ? -23.348 -41.467 -8.333  1.00 71.90  ? 431 LYS A N   1 
ATOM   3387  C CA  . LYS A 1 431 ? -23.363 -42.787 -8.955  1.00 82.98  ? 431 LYS A CA  1 
ATOM   3388  C C   . LYS A 1 431 ? -24.810 -43.187 -9.324  1.00 88.72  ? 431 LYS A C   1 
ATOM   3389  O O   . LYS A 1 431 ? -25.070 -43.503 -10.481 1.00 94.07  ? 431 LYS A O   1 
ATOM   3390  C CB  . LYS A 1 431 ? -22.652 -43.805 -8.051  1.00 79.08  ? 431 LYS A CB  1 
ATOM   3391  C CG  . LYS A 1 431 ? -21.678 -44.757 -8.745  1.00 95.52  ? 431 LYS A CG  1 
ATOM   3392  C CD  . LYS A 1 431 ? -22.123 -45.307 -10.120 1.00 118.73 ? 431 LYS A CD  1 
ATOM   3393  C CE  . LYS A 1 431 ? -23.420 -46.105 -10.140 1.00 130.84 ? 431 LYS A CE  1 
ATOM   3394  N NZ  . LYS A 1 431 ? -23.215 -47.571 -10.014 1.00 130.76 ? 431 LYS A NZ  1 
ATOM   3395  N N   . TRP A 1 432 ? -25.770 -43.128 -8.381  1.00 87.53  ? 432 TRP A N   1 
ATOM   3396  C CA  . TRP A 1 432 ? -27.163 -43.503 -8.636  1.00 91.05  ? 432 TRP A CA  1 
ATOM   3397  C C   . TRP A 1 432 ? -27.851 -42.602 -9.667  1.00 88.54  ? 432 TRP A C   1 
ATOM   3398  O O   . TRP A 1 432 ? -28.855 -42.993 -10.254 1.00 94.35  ? 432 TRP A O   1 
ATOM   3399  C CB  . TRP A 1 432 ? -28.005 -43.535 -7.344  1.00 105.53 ? 432 TRP A CB  1 
ATOM   3400  C CG  . TRP A 1 432 ? -27.785 -44.748 -6.492  1.00 119.02 ? 432 TRP A CG  1 
ATOM   3401  C CD1 . TRP A 1 432 ? -27.770 -46.045 -6.916  1.00 118.69 ? 432 TRP A CD1 1 
ATOM   3402  C CD2 . TRP A 1 432 ? -27.574 -44.786 -5.065  1.00 125.90 ? 432 TRP A CD2 1 
ATOM   3403  N NE1 . TRP A 1 432 ? -27.553 -46.886 -5.859  1.00 123.90 ? 432 TRP A NE1 1 
ATOM   3404  C CE2 . TRP A 1 432 ? -27.423 -46.145 -4.710  1.00 121.12 ? 432 TRP A CE2 1 
ATOM   3405  C CE3 . TRP A 1 432 ? -27.506 -43.816 -4.053  1.00 117.89 ? 432 TRP A CE3 1 
ATOM   3406  C CZ2 . TRP A 1 432 ? -27.189 -46.547 -3.391  1.00 109.29 ? 432 TRP A CZ2 1 
ATOM   3407  C CZ3 . TRP A 1 432 ? -27.264 -44.216 -2.755  1.00 107.50 ? 432 TRP A CZ3 1 
ATOM   3408  C CH2 . TRP A 1 432 ? -27.106 -45.565 -2.431  1.00 103.94 ? 432 TRP A CH2 1 
ATOM   3409  N N   . ALA A 1 433 ? -27.379 -41.375 -9.865  1.00 93.20  ? 433 ALA A N   1 
ATOM   3410  C CA  . ALA A 1 433 ? -27.956 -40.534 -10.904 1.00 100.73 ? 433 ALA A CA  1 
ATOM   3411  C C   . ALA A 1 433 ? -27.338 -40.866 -12.269 1.00 91.69  ? 433 ALA A C   1 
ATOM   3412  O O   . ALA A 1 433 ? -27.861 -40.436 -13.295 1.00 73.24  ? 433 ALA A O   1 
ATOM   3413  C CB  . ALA A 1 433 ? -27.769 -39.078 -10.550 1.00 113.21 ? 433 ALA A CB  1 
ATOM   3414  N N   . GLY A 1 434 ? -26.189 -41.541 -12.248 1.00 81.35  ? 434 GLY A N   1 
ATOM   3415  C CA  . GLY A 1 434 ? -25.484 -41.858 -13.502 1.00 87.23  ? 434 GLY A CA  1 
ATOM   3416  C C   . GLY A 1 434 ? -24.577 -40.729 -13.947 1.00 89.81  ? 434 GLY A C   1 
ATOM   3417  O O   . GLY A 1 434 ? -24.987 -39.985 -14.853 1.00 93.04  ? 434 GLY A O   1 
ATOM   3418  N N   . ILE A 1 435 ? -23.388 -40.605 -13.352 1.00 93.72  ? 435 ILE A N   1 
ATOM   3419  C CA  . ILE A 1 435 ? -22.494 -39.493 -13.671 1.00 94.28  ? 435 ILE A CA  1 
ATOM   3420  C C   . ILE A 1 435 ? -21.046 -40.003 -13.770 1.00 85.95  ? 435 ILE A C   1 
ATOM   3421  O O   . ILE A 1 435 ? -20.391 -40.130 -12.710 1.00 73.91  ? 435 ILE A O   1 
ATOM   3422  C CB  . ILE A 1 435 ? -22.654 -38.337 -12.652 1.00 91.86  ? 435 ILE A CB  1 
ATOM   3423  C CG1 . ILE A 1 435 ? -24.067 -37.741 -12.698 1.00 85.92  ? 435 ILE A CG1 1 
ATOM   3424  C CG2 . ILE A 1 435 ? -21.582 -37.270 -12.854 1.00 93.25  ? 435 ILE A CG2 1 
ATOM   3425  C CD1 . ILE A 1 435 ? -24.293 -36.589 -11.747 1.00 81.61  ? 435 ILE A CD1 1 
ATOM   3426  N N   . SER B 1 2   ? -8.033  -16.976 7.587   1.00 75.20  ? 2   SER B N   1 
ATOM   3427  C CA  . SER B 1 2   ? -6.863  -17.892 7.586   1.00 80.26  ? 2   SER B CA  1 
ATOM   3428  C C   . SER B 1 2   ? -6.752  -18.576 6.227   1.00 81.67  ? 2   SER B C   1 
ATOM   3429  O O   . SER B 1 2   ? -7.619  -18.410 5.372   1.00 75.03  ? 2   SER B O   1 
ATOM   3430  C CB  . SER B 1 2   ? -6.984  -18.901 8.712   1.00 86.41  ? 2   SER B CB  1 
ATOM   3431  O OG  . SER B 1 2   ? -8.277  -19.503 8.720   1.00 82.16  ? 2   SER B OG  1 
ATOM   3432  N N   . PHE B 1 3   ? -5.697  -19.380 6.056   1.00 83.14  ? 3   PHE B N   1 
ATOM   3433  C CA  . PHE B 1 3   ? -5.605  -20.242 4.892   1.00 84.81  ? 3   PHE B CA  1 
ATOM   3434  C C   . PHE B 1 3   ? -6.774  -21.234 4.893   1.00 79.61  ? 3   PHE B C   1 
ATOM   3435  O O   . PHE B 1 3   ? -7.388  -21.418 3.845   1.00 72.91  ? 3   PHE B O   1 
ATOM   3436  C CB  . PHE B 1 3   ? -4.242  -20.936 4.815   1.00 94.78  ? 3   PHE B CB  1 
ATOM   3437  C CG  . PHE B 1 3   ? -4.037  -21.715 3.536   1.00 122.78 ? 3   PHE B CG  1 
ATOM   3438  C CD1 . PHE B 1 3   ? -4.130  -21.081 2.297   1.00 133.82 ? 3   PHE B CD1 1 
ATOM   3439  C CD2 . PHE B 1 3   ? -3.794  -23.086 3.557   1.00 123.31 ? 3   PHE B CD2 1 
ATOM   3440  C CE1 . PHE B 1 3   ? -3.969  -21.792 1.114   1.00 128.73 ? 3   PHE B CE1 1 
ATOM   3441  C CE2 . PHE B 1 3   ? -3.619  -23.791 2.372   1.00 126.75 ? 3   PHE B CE2 1 
ATOM   3442  C CZ  . PHE B 1 3   ? -3.699  -23.143 1.154   1.00 128.98 ? 3   PHE B CZ  1 
ATOM   3443  N N   . LEU B 1 4   ? -7.088  -21.840 6.060   1.00 69.55  ? 4   LEU B N   1 
ATOM   3444  C CA  . LEU B 1 4   ? -8.139  -22.853 6.211   1.00 60.77  ? 4   LEU B CA  1 
ATOM   3445  C C   . LEU B 1 4   ? -9.509  -22.326 5.765   1.00 54.76  ? 4   LEU B C   1 
ATOM   3446  O O   . LEU B 1 4   ? -10.223 -23.002 5.034   1.00 49.92  ? 4   LEU B O   1 
ATOM   3447  C CB  . LEU B 1 4   ? -8.177  -23.321 7.672   1.00 63.88  ? 4   LEU B CB  1 
ATOM   3448  C CG  . LEU B 1 4   ? -9.293  -24.292 8.079   1.00 70.09  ? 4   LEU B CG  1 
ATOM   3449  C CD1 . LEU B 1 4   ? -9.304  -25.530 7.193   1.00 70.94  ? 4   LEU B CD1 1 
ATOM   3450  C CD2 . LEU B 1 4   ? -9.165  -24.698 9.547   1.00 67.20  ? 4   LEU B CD2 1 
ATOM   3451  N N   . LYS B 1 5   ? -9.877  -21.111 6.167   1.00 51.25  ? 5   LYS B N   1 
ATOM   3452  C CA  . LYS B 1 5   ? -11.160 -20.551 5.777   1.00 54.04  ? 5   LYS B CA  1 
ATOM   3453  C C   . LYS B 1 5   ? -11.212 -20.278 4.272   1.00 59.67  ? 5   LYS B C   1 
ATOM   3454  O O   . LYS B 1 5   ? -12.241 -20.504 3.646   1.00 64.32  ? 5   LYS B O   1 
ATOM   3455  C CB  . LYS B 1 5   ? -11.429 -19.297 6.613   1.00 54.90  ? 5   LYS B CB  1 
ATOM   3456  C CG  . LYS B 1 5   ? -12.814 -18.686 6.459   1.00 54.34  ? 5   LYS B CG  1 
ATOM   3457  C CD  . LYS B 1 5   ? -13.242 -17.938 7.687   1.00 57.86  ? 5   LYS B CD  1 
ATOM   3458  C CE  . LYS B 1 5   ? -14.471 -17.080 7.472   1.00 63.20  ? 5   LYS B CE  1 
ATOM   3459  N NZ  . LYS B 1 5   ? -15.031 -16.591 8.761   1.00 61.69  ? 5   LYS B NZ  1 
ATOM   3460  N N   . GLU B 1 6   ? -10.116 -19.779 3.682   1.00 67.20  ? 6   GLU B N   1 
ATOM   3461  C CA  . GLU B 1 6   ? -10.065 -19.538 2.245   1.00 66.20  ? 6   GLU B CA  1 
ATOM   3462  C C   . GLU B 1 6   ? -10.162 -20.864 1.490   1.00 57.90  ? 6   GLU B C   1 
ATOM   3463  O O   . GLU B 1 6   ? -10.913 -20.965 0.532   1.00 54.59  ? 6   GLU B O   1 
ATOM   3464  C CB  . GLU B 1 6   ? -8.786  -18.796 1.845   1.00 79.80  ? 6   GLU B CB  1 
ATOM   3465  C CG  . GLU B 1 6   ? -8.818  -17.293 2.128   1.00 97.24  ? 6   GLU B CG  1 
ATOM   3466  C CD  . GLU B 1 6   ? -7.479  -16.561 2.051   1.00 100.42 ? 6   GLU B CD  1 
ATOM   3467  O OE1 . GLU B 1 6   ? -6.463  -17.190 1.695   1.00 107.27 ? 6   GLU B OE1 1 
ATOM   3468  O OE2 . GLU B 1 6   ? -7.444  -15.371 2.390   1.00 101.87 ? 6   GLU B OE2 1 
ATOM   3469  N N   . LYS B 1 7   ? -9.375  -21.856 1.920   1.00 60.79  ? 7   LYS B N   1 
ATOM   3470  C CA  . LYS B 1 7   ? -9.326  -23.193 1.334   1.00 69.95  ? 7   LYS B CA  1 
ATOM   3471  C C   . LYS B 1 7   ? -10.712 -23.838 1.384   1.00 70.16  ? 7   LYS B C   1 
ATOM   3472  O O   . LYS B 1 7   ? -11.133 -24.527 0.454   1.00 71.91  ? 7   LYS B O   1 
ATOM   3473  C CB  . LYS B 1 7   ? -8.269  -24.012 2.092   1.00 78.29  ? 7   LYS B CB  1 
ATOM   3474  C CG  . LYS B 1 7   ? -8.314  -25.536 1.983   1.00 83.84  ? 7   LYS B CG  1 
ATOM   3475  C CD  . LYS B 1 7   ? -8.043  -26.104 0.606   1.00 97.64  ? 7   LYS B CD  1 
ATOM   3476  C CE  . LYS B 1 7   ? -6.608  -25.944 0.154   1.00 105.12 ? 7   LYS B CE  1 
ATOM   3477  N NZ  . LYS B 1 7   ? -6.534  -25.670 -1.304  1.00 106.49 ? 7   LYS B NZ  1 
ATOM   3478  N N   . LEU B 1 8   ? -11.417 -23.609 2.489   1.00 64.29  ? 8   LEU B N   1 
ATOM   3479  C CA  . LEU B 1 8   ? -12.713 -24.217 2.716   1.00 62.52  ? 8   LEU B CA  1 
ATOM   3480  C C   . LEU B 1 8   ? -13.749 -23.510 1.851   1.00 55.19  ? 8   LEU B C   1 
ATOM   3481  O O   . LEU B 1 8   ? -14.692 -24.128 1.391   1.00 54.84  ? 8   LEU B O   1 
ATOM   3482  C CB  . LEU B 1 8   ? -13.018 -24.127 4.216   1.00 67.84  ? 8   LEU B CB  1 
ATOM   3483  C CG  . LEU B 1 8   ? -14.382 -24.625 4.681   1.00 71.70  ? 8   LEU B CG  1 
ATOM   3484  C CD1 . LEU B 1 8   ? -14.527 -26.117 4.423   1.00 74.58  ? 8   LEU B CD1 1 
ATOM   3485  C CD2 . LEU B 1 8   ? -14.562 -24.321 6.162   1.00 74.32  ? 8   LEU B CD2 1 
ATOM   3486  N N   . ALA B 1 9   ? -13.552 -22.222 1.584   1.00 57.97  ? 9   ALA B N   1 
ATOM   3487  C CA  . ALA B 1 9   ? -14.452 -21.490 0.705   1.00 55.44  ? 9   ALA B CA  1 
ATOM   3488  C C   . ALA B 1 9   ? -14.328 -22.009 -0.728  1.00 55.23  ? 9   ALA B C   1 
ATOM   3489  O O   . ALA B 1 9   ? -15.311 -21.999 -1.462  1.00 55.14  ? 9   ALA B O   1 
ATOM   3490  C CB  . ALA B 1 9   ? -14.165 -20.005 0.778   1.00 51.50  ? 9   ALA B CB  1 
ATOM   3491  N N   . GLU B 1 10  ? -13.110 -22.421 -1.118  1.00 57.88  ? 10  GLU B N   1 
ATOM   3492  C CA  . GLU B 1 10  ? -12.842 -22.940 -2.450  1.00 61.15  ? 10  GLU B CA  1 
ATOM   3493  C C   . GLU B 1 10  ? -13.593 -24.244 -2.658  1.00 61.61  ? 10  GLU B C   1 
ATOM   3494  O O   . GLU B 1 10  ? -14.235 -24.420 -3.694  1.00 64.60  ? 10  GLU B O   1 
ATOM   3495  C CB  . GLU B 1 10  ? -11.362 -23.257 -2.660  1.00 69.16  ? 10  GLU B CB  1 
ATOM   3496  C CG  . GLU B 1 10  ? -10.481 -22.035 -2.836  1.00 82.13  ? 10  GLU B CG  1 
ATOM   3497  C CD  . GLU B 1 10  ? -9.114  -22.376 -3.414  1.00 91.50  ? 10  GLU B CD  1 
ATOM   3498  O OE1 . GLU B 1 10  ? -8.499  -23.381 -2.934  1.00 78.49  ? 10  GLU B OE1 1 
ATOM   3499  O OE2 . GLU B 1 10  ? -8.674  -21.645 -4.339  1.00 91.72  ? 10  GLU B OE2 1 
ATOM   3500  N N   . LYS B 1 11  ? -13.503 -25.134 -1.655  1.00 55.82  ? 11  LYS B N   1 
ATOM   3501  C CA  . LYS B 1 11  ? -14.143 -26.437 -1.721  1.00 50.42  ? 11  LYS B CA  1 
ATOM   3502  C C   . LYS B 1 11  ? -15.663 -26.298 -1.788  1.00 49.06  ? 11  LYS B C   1 
ATOM   3503  O O   . LYS B 1 11  ? -16.335 -27.123 -2.411  1.00 54.80  ? 11  LYS B O   1 
ATOM   3504  C CB  . LYS B 1 11  ? -13.757 -27.276 -0.509  1.00 49.09  ? 11  LYS B CB  1 
ATOM   3505  C CG  . LYS B 1 11  ? -12.285 -27.615 -0.413  1.00 54.87  ? 11  LYS B CG  1 
ATOM   3506  C CD  . LYS B 1 11  ? -11.889 -28.793 -1.258  1.00 61.80  ? 11  LYS B CD  1 
ATOM   3507  C CE  . LYS B 1 11  ? -10.386 -28.889 -1.409  1.00 68.88  ? 11  LYS B CE  1 
ATOM   3508  N NZ  . LYS B 1 11  ? -9.958  -30.298 -1.583  1.00 73.24  ? 11  LYS B NZ  1 
ATOM   3509  N N   . ILE B 1 12  ? -16.185 -25.263 -1.126  1.00 47.12  ? 12  ILE B N   1 
ATOM   3510  C CA  . ILE B 1 12  ? -17.616 -25.048 -1.029  1.00 54.78  ? 12  ILE B CA  1 
ATOM   3511  C C   . ILE B 1 12  ? -18.146 -24.642 -2.401  1.00 57.78  ? 12  ILE B C   1 
ATOM   3512  O O   . ILE B 1 12  ? -19.187 -25.130 -2.821  1.00 56.19  ? 12  ILE B O   1 
ATOM   3513  C CB  . ILE B 1 12  ? -17.935 -24.014 0.076   1.00 54.08  ? 12  ILE B CB  1 
ATOM   3514  C CG1 . ILE B 1 12  ? -17.826 -24.650 1.470   1.00 51.25  ? 12  ILE B CG1 1 
ATOM   3515  C CG2 . ILE B 1 12  ? -19.292 -23.349 -0.151  1.00 52.60  ? 12  ILE B CG2 1 
ATOM   3516  C CD1 . ILE B 1 12  ? -17.807 -23.665 2.633   1.00 54.77  ? 12  ILE B CD1 1 
ATOM   3517  N N   . ALA B 1 13  ? -17.402 -23.760 -3.079  1.00 59.21  ? 13  ALA B N   1 
ATOM   3518  C CA  . ALA B 1 13  ? -17.777 -23.262 -4.389  1.00 58.50  ? 13  ALA B CA  1 
ATOM   3519  C C   . ALA B 1 13  ? -17.720 -24.384 -5.424  1.00 61.33  ? 13  ALA B C   1 
ATOM   3520  O O   . ALA B 1 13  ? -18.564 -24.405 -6.320  1.00 55.81  ? 13  ALA B O   1 
ATOM   3521  C CB  . ALA B 1 13  ? -16.885 -22.115 -4.766  1.00 61.19  ? 13  ALA B CB  1 
ATOM   3522  N N   . GLN B 1 14  ? -16.740 -25.301 -5.301  1.00 59.20  ? 14  GLN B N   1 
ATOM   3523  C CA  . GLN B 1 14  ? -16.691 -26.484 -6.155  1.00 66.54  ? 14  GLN B CA  1 
ATOM   3524  C C   . GLN B 1 14  ? -17.876 -27.428 -5.905  1.00 74.70  ? 14  GLN B C   1 
ATOM   3525  O O   . GLN B 1 14  ? -18.358 -28.057 -6.839  1.00 71.95  ? 14  GLN B O   1 
ATOM   3526  C CB  . GLN B 1 14  ? -15.383 -27.253 -5.954  1.00 66.72  ? 14  GLN B CB  1 
ATOM   3527  C CG  . GLN B 1 14  ? -14.214 -26.701 -6.759  1.00 71.37  ? 14  GLN B CG  1 
ATOM   3528  C CD  . GLN B 1 14  ? -12.901 -26.883 -6.034  1.00 76.51  ? 14  GLN B CD  1 
ATOM   3529  O OE1 . GLN B 1 14  ? -12.554 -27.969 -5.578  1.00 78.93  ? 14  GLN B OE1 1 
ATOM   3530  N NE2 . GLN B 1 14  ? -12.178 -25.789 -5.870  1.00 88.91  ? 14  GLN B NE2 1 
ATOM   3531  N N   . HIS B 1 15  ? -18.355 -27.537 -4.654  1.00 78.69  ? 15  HIS B N   1 
ATOM   3532  C CA  . HIS B 1 15  ? -19.297 -28.584 -4.260  1.00 66.91  ? 15  HIS B CA  1 
ATOM   3533  C C   . HIS B 1 15  ? -20.751 -28.133 -4.461  1.00 58.77  ? 15  HIS B C   1 
ATOM   3534  O O   . HIS B 1 15  ? -21.648 -28.943 -4.645  1.00 59.20  ? 15  HIS B O   1 
ATOM   3535  C CB  . HIS B 1 15  ? -19.006 -28.989 -2.803  1.00 66.13  ? 15  HIS B CB  1 
ATOM   3536  C CG  . HIS B 1 15  ? -19.595 -30.287 -2.333  1.00 68.83  ? 15  HIS B CG  1 
ATOM   3537  N ND1 . HIS B 1 15  ? -20.950 -30.570 -2.310  1.00 66.52  ? 15  HIS B ND1 1 
ATOM   3538  C CD2 . HIS B 1 15  ? -18.945 -31.372 -1.805  1.00 72.70  ? 15  HIS B CD2 1 
ATOM   3539  C CE1 . HIS B 1 15  ? -21.122 -31.802 -1.813  1.00 71.43  ? 15  HIS B CE1 1 
ATOM   3540  N NE2 . HIS B 1 15  ? -19.884 -32.326 -1.497  1.00 69.11  ? 15  HIS B NE2 1 
ATOM   3541  N N   . ARG B 1 16  ? -21.008 -26.832 -4.404  1.00 53.83  ? 16  ARG B N   1 
ATOM   3542  C CA  . ARG B 1 16  ? -22.377 -26.338 -4.474  1.00 62.75  ? 16  ARG B CA  1 
ATOM   3543  C C   . ARG B 1 16  ? -23.000 -26.742 -5.806  1.00 60.44  ? 16  ARG B C   1 
ATOM   3544  O O   . ARG B 1 16  ? -24.117 -27.233 -5.803  1.00 64.18  ? 16  ARG B O   1 
ATOM   3545  C CB  . ARG B 1 16  ? -22.474 -24.827 -4.181  1.00 63.54  ? 16  ARG B CB  1 
ATOM   3546  C CG  . ARG B 1 16  ? -22.421 -24.502 -2.688  1.00 66.87  ? 16  ARG B CG  1 
ATOM   3547  C CD  . ARG B 1 16  ? -23.059 -23.205 -2.225  1.00 65.99  ? 16  ARG B CD  1 
ATOM   3548  N NE  . ARG B 1 16  ? -22.115 -22.225 -1.692  1.00 61.99  ? 16  ARG B NE  1 
ATOM   3549  C CZ  . ARG B 1 16  ? -22.301 -21.504 -0.583  1.00 62.01  ? 16  ARG B CZ  1 
ATOM   3550  N NH1 . ARG B 1 16  ? -22.215 -22.054 0.612   1.00 64.01  ? 16  ARG B NH1 1 
ATOM   3551  N NH2 . ARG B 1 16  ? -22.519 -20.203 -0.658  1.00 64.37  ? 16  ARG B NH2 1 
ATOM   3552  N N   . PRO B 1 17  ? -22.336 -26.571 -6.977  1.00 71.99  ? 17  PRO B N   1 
ATOM   3553  C CA  . PRO B 1 17  ? -22.901 -27.006 -8.263  1.00 72.41  ? 17  PRO B CA  1 
ATOM   3554  C C   . PRO B 1 17  ? -23.331 -28.477 -8.314  1.00 71.89  ? 17  PRO B C   1 
ATOM   3555  O O   . PRO B 1 17  ? -24.439 -28.788 -8.759  1.00 63.20  ? 17  PRO B O   1 
ATOM   3556  C CB  . PRO B 1 17  ? -21.754 -26.746 -9.247  1.00 69.30  ? 17  PRO B CB  1 
ATOM   3557  C CG  . PRO B 1 17  ? -21.022 -25.583 -8.628  1.00 71.22  ? 17  PRO B CG  1 
ATOM   3558  C CD  . PRO B 1 17  ? -21.043 -25.896 -7.150  1.00 71.78  ? 17  PRO B CD  1 
ATOM   3559  N N   . ARG B 1 18  ? -22.460 -29.376 -7.830  1.00 69.04  ? 18  ARG B N   1 
ATOM   3560  C CA  . ARG B 1 18  ? -22.758 -30.800 -7.749  1.00 63.09  ? 18  ARG B CA  1 
ATOM   3561  C C   . ARG B 1 18  ? -24.100 -31.041 -7.053  1.00 71.36  ? 18  ARG B C   1 
ATOM   3562  O O   . ARG B 1 18  ? -24.883 -31.866 -7.516  1.00 77.01  ? 18  ARG B O   1 
ATOM   3563  C CB  . ARG B 1 18  ? -21.667 -31.530 -6.959  1.00 62.35  ? 18  ARG B CB  1 
ATOM   3564  C CG  . ARG B 1 18  ? -20.285 -31.513 -7.584  1.00 58.79  ? 18  ARG B CG  1 
ATOM   3565  C CD  . ARG B 1 18  ? -19.262 -32.103 -6.640  1.00 60.13  ? 18  ARG B CD  1 
ATOM   3566  N NE  . ARG B 1 18  ? -19.554 -33.480 -6.273  1.00 68.19  ? 18  ARG B NE  1 
ATOM   3567  C CZ  . ARG B 1 18  ? -18.963 -34.146 -5.282  1.00 75.99  ? 18  ARG B CZ  1 
ATOM   3568  N NH1 . ARG B 1 18  ? -18.266 -33.503 -4.358  1.00 75.83  ? 18  ARG B NH1 1 
ATOM   3569  N NH2 . ARG B 1 18  ? -19.067 -35.467 -5.214  1.00 69.19  ? 18  ARG B NH2 1 
ATOM   3570  N N   . THR B 1 19  ? -24.323 -30.323 -5.935  1.00 73.62  ? 19  THR B N   1 
ATOM   3571  C CA  . THR B 1 19  ? -25.510 -30.441 -5.096  1.00 65.47  ? 19  THR B CA  1 
ATOM   3572  C C   . THR B 1 19  ? -26.701 -29.829 -5.832  1.00 62.60  ? 19  THR B C   1 
ATOM   3573  O O   . THR B 1 19  ? -27.755 -30.439 -5.871  1.00 67.08  ? 19  THR B O   1 
ATOM   3574  C CB  . THR B 1 19  ? -25.285 -29.810 -3.702  1.00 69.89  ? 19  THR B CB  1 
ATOM   3575  O OG1 . THR B 1 19  ? -24.295 -30.515 -2.943  1.00 70.52  ? 19  THR B OG1 1 
ATOM   3576  C CG2 . THR B 1 19  ? -26.537 -29.756 -2.849  1.00 66.77  ? 19  THR B CG2 1 
ATOM   3577  N N   . THR B 1 20  ? -26.532 -28.633 -6.412  1.00 64.65  ? 20  THR B N   1 
ATOM   3578  C CA  . THR B 1 20  ? -27.603 -27.934 -7.121  1.00 73.35  ? 20  THR B CA  1 
ATOM   3579  C C   . THR B 1 20  ? -28.128 -28.768 -8.291  1.00 73.07  ? 20  THR B C   1 
ATOM   3580  O O   . THR B 1 20  ? -29.311 -28.696 -8.624  1.00 66.88  ? 20  THR B O   1 
ATOM   3581  C CB  . THR B 1 20  ? -27.158 -26.584 -7.709  1.00 69.93  ? 20  THR B CB  1 
ATOM   3582  O OG1 . THR B 1 20  ? -26.308 -25.933 -6.765  1.00 78.92  ? 20  THR B OG1 1 
ATOM   3583  C CG2 . THR B 1 20  ? -28.318 -25.675 -8.063  1.00 63.52  ? 20  THR B CG2 1 
ATOM   3584  N N   . ARG B 1 21  ? -27.221 -29.522 -8.918  1.00 70.65  ? 21  ARG B N   1 
ATOM   3585  C CA  . ARG B 1 21  ? -27.535 -30.348 -10.069 1.00 72.24  ? 21  ARG B CA  1 
ATOM   3586  C C   . ARG B 1 21  ? -28.390 -31.536 -9.621  1.00 68.05  ? 21  ARG B C   1 
ATOM   3587  O O   . ARG B 1 21  ? -29.478 -31.766 -10.149 1.00 73.71  ? 21  ARG B O   1 
ATOM   3588  C CB  . ARG B 1 21  ? -26.214 -30.769 -10.719 1.00 76.57  ? 21  ARG B CB  1 
ATOM   3589  C CG  . ARG B 1 21  ? -26.320 -31.276 -12.147 1.00 78.58  ? 21  ARG B CG  1 
ATOM   3590  C CD  . ARG B 1 21  ? -24.926 -31.680 -12.617 1.00 80.10  ? 21  ARG B CD  1 
ATOM   3591  N NE  . ARG B 1 21  ? -24.893 -31.995 -14.037 1.00 91.59  ? 21  ARG B NE  1 
ATOM   3592  C CZ  . ARG B 1 21  ? -24.505 -33.155 -14.567 1.00 90.63  ? 21  ARG B CZ  1 
ATOM   3593  N NH1 . ARG B 1 21  ? -23.740 -34.003 -13.898 1.00 76.06  ? 21  ARG B NH1 1 
ATOM   3594  N NH2 . ARG B 1 21  ? -24.875 -33.450 -15.799 1.00 92.00  ? 21  ARG B NH2 1 
ATOM   3595  N N   . LEU B 1 22  ? -27.915 -32.267 -8.607  1.00 63.23  ? 22  LEU B N   1 
ATOM   3596  C CA  . LEU B 1 22  ? -28.661 -33.376 -8.039  1.00 61.03  ? 22  LEU B CA  1 
ATOM   3597  C C   . LEU B 1 22  ? -30.101 -32.977 -7.741  1.00 64.42  ? 22  LEU B C   1 
ATOM   3598  O O   . LEU B 1 22  ? -30.990 -33.779 -7.934  1.00 70.64  ? 22  LEU B O   1 
ATOM   3599  C CB  . LEU B 1 22  ? -27.971 -33.836 -6.756  1.00 60.89  ? 22  LEU B CB  1 
ATOM   3600  C CG  . LEU B 1 22  ? -26.730 -34.695 -6.942  1.00 66.62  ? 22  LEU B CG  1 
ATOM   3601  C CD1 . LEU B 1 22  ? -25.993 -34.847 -5.619  1.00 71.40  ? 22  LEU B CD1 1 
ATOM   3602  C CD2 . LEU B 1 22  ? -27.099 -36.062 -7.509  1.00 70.24  ? 22  LEU B CD2 1 
ATOM   3603  N N   . LEU B 1 23  ? -30.332 -31.759 -7.246  1.00 69.95  ? 23  LEU B N   1 
ATOM   3604  C CA  . LEU B 1 23  ? -31.658 -31.360 -6.803  1.00 76.78  ? 23  LEU B CA  1 
ATOM   3605  C C   . LEU B 1 23  ? -32.543 -31.028 -7.994  1.00 79.46  ? 23  LEU B C   1 
ATOM   3606  O O   . LEU B 1 23  ? -33.677 -31.495 -8.050  1.00 86.02  ? 23  LEU B O   1 
ATOM   3607  C CB  . LEU B 1 23  ? -31.578 -30.149 -5.870  1.00 83.81  ? 23  LEU B CB  1 
ATOM   3608  C CG  . LEU B 1 23  ? -31.381 -30.450 -4.380  1.00 87.32  ? 23  LEU B CG  1 
ATOM   3609  C CD1 . LEU B 1 23  ? -31.761 -29.236 -3.531  1.00 81.27  ? 23  LEU B CD1 1 
ATOM   3610  C CD2 . LEU B 1 23  ? -32.161 -31.686 -3.940  1.00 80.53  ? 23  LEU B CD2 1 
ATOM   3611  N N   . LYS B 1 24  ? -32.024 -30.198 -8.907  1.00 91.39  ? 24  LYS B N   1 
ATOM   3612  C CA  . LYS B 1 24  ? -32.794 -29.707 -10.042 1.00 96.67  ? 24  LYS B CA  1 
ATOM   3613  C C   . LYS B 1 24  ? -33.019 -30.817 -11.073 1.00 93.05  ? 24  LYS B C   1 
ATOM   3614  O O   . LYS B 1 24  ? -34.126 -30.945 -11.593 1.00 85.40  ? 24  LYS B O   1 
ATOM   3615  C CB  . LYS B 1 24  ? -32.100 -28.521 -10.712 1.00 98.65  ? 24  LYS B CB  1 
ATOM   3616  C CG  . LYS B 1 24  ? -33.034 -27.633 -11.515 1.00 105.81 ? 24  LYS B CG  1 
ATOM   3617  C CD  . LYS B 1 24  ? -32.351 -26.438 -12.094 1.00 106.98 ? 24  LYS B CD  1 
ATOM   3618  C CE  . LYS B 1 24  ? -33.300 -25.600 -12.926 1.00 99.93  ? 24  LYS B CE  1 
ATOM   3619  N NZ  . LYS B 1 24  ? -32.684 -24.304 -13.276 1.00 96.68  ? 24  LYS B NZ  1 
ATOM   3620  N N   . GLU B 1 25  ? -31.982 -31.621 -11.359 1.00 85.41  ? 25  GLU B N   1 
ATOM   3621  C CA  . GLU B 1 25  ? -32.031 -32.562 -12.468 1.00 85.73  ? 25  GLU B CA  1 
ATOM   3622  C C   . GLU B 1 25  ? -32.347 -33.995 -12.016 1.00 84.55  ? 25  GLU B C   1 
ATOM   3623  O O   . GLU B 1 25  ? -32.676 -34.827 -12.854 1.00 83.54  ? 25  GLU B O   1 
ATOM   3624  C CB  . GLU B 1 25  ? -30.700 -32.578 -13.229 1.00 93.98  ? 25  GLU B CB  1 
ATOM   3625  C CG  . GLU B 1 25  ? -30.484 -31.445 -14.223 1.00 97.72  ? 25  GLU B CG  1 
ATOM   3626  C CD  . GLU B 1 25  ? -29.202 -31.600 -15.032 1.00 107.10 ? 25  GLU B CD  1 
ATOM   3627  O OE1 . GLU B 1 25  ? -29.058 -32.646 -15.720 1.00 102.56 ? 25  GLU B OE1 1 
ATOM   3628  O OE2 . GLU B 1 25  ? -28.347 -30.683 -14.978 1.00 107.20 ? 25  GLU B OE2 1 
ATOM   3629  N N   . PHE B 1 26  ? -32.216 -34.330 -10.722 1.00 86.25  ? 26  PHE B N   1 
ATOM   3630  C CA  . PHE B 1 26  ? -32.288 -35.732 -10.313 1.00 78.34  ? 26  PHE B CA  1 
ATOM   3631  C C   . PHE B 1 26  ? -33.041 -35.918 -8.987  1.00 65.20  ? 26  PHE B C   1 
ATOM   3632  O O   . PHE B 1 26  ? -32.925 -36.957 -8.334  1.00 50.77  ? 26  PHE B O   1 
ATOM   3633  C CB  . PHE B 1 26  ? -30.870 -36.310 -10.305 1.00 79.64  ? 26  PHE B CB  1 
ATOM   3634  C CG  . PHE B 1 26  ? -30.202 -36.318 -11.661 1.00 94.73  ? 26  PHE B CG  1 
ATOM   3635  C CD1 . PHE B 1 26  ? -30.517 -37.278 -12.614 1.00 102.98 ? 26  PHE B CD1 1 
ATOM   3636  C CD2 . PHE B 1 26  ? -29.287 -35.333 -12.008 1.00 107.55 ? 26  PHE B CD2 1 
ATOM   3637  C CE1 . PHE B 1 26  ? -29.910 -37.266 -13.862 1.00 107.68 ? 26  PHE B CE1 1 
ATOM   3638  C CE2 . PHE B 1 26  ? -28.685 -35.318 -13.261 1.00 104.50 ? 26  PHE B CE2 1 
ATOM   3639  C CZ  . PHE B 1 26  ? -28.998 -36.284 -14.185 1.00 104.42 ? 26  PHE B CZ  1 
ATOM   3640  N N   . GLY B 1 27  ? -33.897 -34.941 -8.652  1.00 67.96  ? 27  GLY B N   1 
ATOM   3641  C CA  . GLY B 1 27  ? -34.619 -34.908 -7.389  1.00 74.72  ? 27  GLY B CA  1 
ATOM   3642  C C   . GLY B 1 27  ? -35.590 -36.078 -7.194  1.00 82.93  ? 27  GLY B C   1 
ATOM   3643  O O   . GLY B 1 27  ? -35.875 -36.437 -6.052  1.00 75.92  ? 27  GLY B O   1 
ATOM   3644  N N   . ASN B 1 28  ? -36.108 -36.653 -8.298  1.00 93.06  ? 28  ASN B N   1 
ATOM   3645  C CA  . ASN B 1 28  ? -37.151 -37.669 -8.244  1.00 81.38  ? 28  ASN B CA  1 
ATOM   3646  C C   . ASN B 1 28  ? -36.558 -39.070 -8.374  1.00 77.39  ? 28  ASN B C   1 
ATOM   3647  O O   . ASN B 1 28  ? -37.278 -40.060 -8.271  1.00 81.34  ? 28  ASN B O   1 
ATOM   3648  C CB  . ASN B 1 28  ? -38.240 -37.415 -9.289  1.00 80.03  ? 28  ASN B CB  1 
ATOM   3649  C CG  . ASN B 1 28  ? -39.383 -36.573 -8.748  1.00 84.91  ? 28  ASN B CG  1 
ATOM   3650  O OD1 . ASN B 1 28  ? -39.190 -35.442 -8.317  1.00 73.25  ? 28  ASN B OD1 1 
ATOM   3651  N ND2 . ASN B 1 28  ? -40.591 -37.114 -8.760  1.00 90.74  ? 28  ASN B ND2 1 
ATOM   3652  N N   . VAL B 1 29  ? -35.242 -39.180 -8.554  1.00 73.85  ? 29  VAL B N   1 
ATOM   3653  C CA  . VAL B 1 29  ? -34.626 -40.498 -8.560  1.00 70.87  ? 29  VAL B CA  1 
ATOM   3654  C C   . VAL B 1 29  ? -34.822 -41.125 -7.181  1.00 71.07  ? 29  VAL B C   1 
ATOM   3655  O O   . VAL B 1 29  ? -34.401 -40.559 -6.175  1.00 74.65  ? 29  VAL B O   1 
ATOM   3656  C CB  . VAL B 1 29  ? -33.137 -40.430 -8.940  1.00 61.84  ? 29  VAL B CB  1 
ATOM   3657  C CG1 . VAL B 1 29  ? -32.454 -41.775 -8.753  1.00 55.40  ? 29  VAL B CG1 1 
ATOM   3658  C CG2 . VAL B 1 29  ? -32.938 -39.896 -10.350 1.00 59.81  ? 29  VAL B CG2 1 
ATOM   3659  N N   . LYS B 1 30  ? -35.471 -42.295 -7.146  1.00 68.63  ? 30  LYS B N   1 
ATOM   3660  C CA  . LYS B 1 30  ? -35.690 -43.034 -5.911  1.00 66.10  ? 30  LYS B CA  1 
ATOM   3661  C C   . LYS B 1 30  ? -34.371 -43.697 -5.524  1.00 62.85  ? 30  LYS B C   1 
ATOM   3662  O O   . LYS B 1 30  ? -33.599 -44.034 -6.409  1.00 61.53  ? 30  LYS B O   1 
ATOM   3663  C CB  . LYS B 1 30  ? -36.836 -44.042 -6.098  1.00 69.32  ? 30  LYS B CB  1 
ATOM   3664  C CG  . LYS B 1 30  ? -36.749 -45.301 -5.242  1.00 72.96  ? 30  LYS B CG  1 
ATOM   3665  C CD  . LYS B 1 30  ? -37.818 -46.331 -5.477  1.00 74.76  ? 30  LYS B CD  1 
ATOM   3666  C CE  . LYS B 1 30  ? -37.304 -47.715 -5.138  1.00 84.33  ? 30  LYS B CE  1 
ATOM   3667  N NZ  . LYS B 1 30  ? -38.299 -48.750 -5.496  1.00 86.48  ? 30  LYS B NZ  1 
ATOM   3668  N N   . ILE B 1 31  ? -34.117 -43.875 -4.214  1.00 65.05  ? 31  ILE B N   1 
ATOM   3669  C CA  . ILE B 1 31  ? -32.878 -44.474 -3.701  1.00 61.01  ? 31  ILE B CA  1 
ATOM   3670  C C   . ILE B 1 31  ? -33.160 -45.500 -2.605  1.00 59.16  ? 31  ILE B C   1 
ATOM   3671  O O   . ILE B 1 31  ? -32.265 -46.270 -2.248  1.00 51.23  ? 31  ILE B O   1 
ATOM   3672  C CB  . ILE B 1 31  ? -31.898 -43.410 -3.145  1.00 64.94  ? 31  ILE B CB  1 
ATOM   3673  C CG1 . ILE B 1 31  ? -32.486 -42.664 -1.931  1.00 61.48  ? 31  ILE B CG1 1 
ATOM   3674  C CG2 . ILE B 1 31  ? -31.446 -42.471 -4.253  1.00 72.56  ? 31  ILE B CG2 1 
ATOM   3675  C CD1 . ILE B 1 31  ? -31.611 -41.612 -1.272  1.00 53.77  ? 31  ILE B CD1 1 
ATOM   3676  N N   . ASP B 1 32  ? -34.344 -45.431 -1.977  1.00 64.41  ? 32  ASP B N   1 
ATOM   3677  C CA  . ASP B 1 32  ? -34.719 -46.460 -1.024  1.00 71.38  ? 32  ASP B CA  1 
ATOM   3678  C C   . ASP B 1 32  ? -36.236 -46.448 -0.847  1.00 77.49  ? 32  ASP B C   1 
ATOM   3679  O O   . ASP B 1 32  ? -36.939 -45.636 -1.445  1.00 71.38  ? 32  ASP B O   1 
ATOM   3680  C CB  . ASP B 1 32  ? -33.949 -46.300 0.293   1.00 70.44  ? 32  ASP B CB  1 
ATOM   3681  C CG  . ASP B 1 32  ? -33.594 -47.611 0.985   1.00 79.40  ? 32  ASP B CG  1 
ATOM   3682  O OD1 . ASP B 1 32  ? -34.092 -48.680 0.541   1.00 78.19  ? 32  ASP B OD1 1 
ATOM   3683  O OD2 . ASP B 1 32  ? -32.830 -47.559 1.976   1.00 83.37  ? 32  ASP B OD2 1 
ATOM   3684  N N   . GLU B 1 33  ? -36.720 -47.408 -0.051  1.00 79.63  ? 33  GLU B N   1 
ATOM   3685  C CA  . GLU B 1 33  ? -38.130 -47.540 0.264   1.00 82.57  ? 33  GLU B CA  1 
ATOM   3686  C C   . GLU B 1 33  ? -38.280 -47.786 1.764   1.00 71.01  ? 33  GLU B C   1 
ATOM   3687  O O   . GLU B 1 33  ? -37.366 -48.315 2.409   1.00 63.90  ? 33  GLU B O   1 
ATOM   3688  C CB  . GLU B 1 33  ? -38.748 -48.669 -0.567  1.00 93.94  ? 33  GLU B CB  1 
ATOM   3689  C CG  . GLU B 1 33  ? -37.997 -49.987 -0.452  1.00 102.52 ? 33  GLU B CG  1 
ATOM   3690  C CD  . GLU B 1 33  ? -38.895 -51.209 -0.417  1.00 117.50 ? 33  GLU B CD  1 
ATOM   3691  O OE1 . GLU B 1 33  ? -39.493 -51.523 -1.473  1.00 117.65 ? 33  GLU B OE1 1 
ATOM   3692  O OE2 . GLU B 1 33  ? -39.018 -51.824 0.679   1.00 117.52 ? 33  GLU B OE2 1 
ATOM   3693  N N   . VAL B 1 34  ? -39.449 -47.400 2.294   1.00 68.20  ? 34  VAL B N   1 
ATOM   3694  C CA  . VAL B 1 34  ? -39.740 -47.523 3.714   1.00 68.65  ? 34  VAL B CA  1 
ATOM   3695  C C   . VAL B 1 34  ? -40.745 -48.653 3.918   1.00 64.99  ? 34  VAL B C   1 
ATOM   3696  O O   . VAL B 1 34  ? -41.831 -48.628 3.337   1.00 54.87  ? 34  VAL B O   1 
ATOM   3697  C CB  . VAL B 1 34  ? -40.287 -46.212 4.316   1.00 70.30  ? 34  VAL B CB  1 
ATOM   3698  C CG1 . VAL B 1 34  ? -40.085 -46.199 5.829   1.00 76.66  ? 34  VAL B CG1 1 
ATOM   3699  C CG2 . VAL B 1 34  ? -39.683 -44.974 3.669   1.00 69.23  ? 34  VAL B CG2 1 
ATOM   3700  N N   . THR B 1 35  ? -40.377 -49.622 4.766   1.00 65.65  ? 35  THR B N   1 
ATOM   3701  C CA  . THR B 1 35  ? -41.290 -50.661 5.210   1.00 62.73  ? 35  THR B CA  1 
ATOM   3702  C C   . THR B 1 35  ? -41.778 -50.327 6.619   1.00 61.80  ? 35  THR B C   1 
ATOM   3703  O O   . THR B 1 35  ? -41.226 -49.446 7.284   1.00 63.62  ? 35  THR B O   1 
ATOM   3704  C CB  . THR B 1 35  ? -40.607 -52.034 5.174   1.00 68.33  ? 35  THR B CB  1 
ATOM   3705  O OG1 . THR B 1 35  ? -39.824 -52.189 6.360   1.00 61.47  ? 35  THR B OG1 1 
ATOM   3706  C CG2 . THR B 1 35  ? -39.738 -52.235 3.945   1.00 72.77  ? 35  THR B CG2 1 
ATOM   3707  N N   . ILE B 1 36  ? -42.800 -51.064 7.071   1.00 58.79  ? 36  ILE B N   1 
ATOM   3708  C CA  . ILE B 1 36  ? -43.396 -50.867 8.388   1.00 60.33  ? 36  ILE B CA  1 
ATOM   3709  C C   . ILE B 1 36  ? -42.363 -51.172 9.487   1.00 59.42  ? 36  ILE B C   1 
ATOM   3710  O O   . ILE B 1 36  ? -42.163 -50.380 10.402  1.00 59.19  ? 36  ILE B O   1 
ATOM   3711  C CB  . ILE B 1 36  ? -44.703 -51.693 8.475   1.00 62.13  ? 36  ILE B CB  1 
ATOM   3712  C CG1 . ILE B 1 36  ? -45.789 -51.046 7.601   1.00 65.57  ? 36  ILE B CG1 1 
ATOM   3713  C CG2 . ILE B 1 36  ? -45.161 -51.906 9.912   1.00 55.97  ? 36  ILE B CG2 1 
ATOM   3714  C CD1 . ILE B 1 36  ? -47.195 -51.574 7.812   1.00 65.05  ? 36  ILE B CD1 1 
ATOM   3715  N N   . SER B 1 37  ? -41.624 -52.263 9.328   1.00 56.32  ? 37  SER B N   1 
ATOM   3716  C CA  . SER B 1 37  ? -40.573 -52.629 10.305  1.00 57.78  ? 37  SER B CA  1 
ATOM   3717  C C   . SER B 1 37  ? -39.591 -51.479 10.494  1.00 65.30  ? 37  SER B C   1 
ATOM   3718  O O   . SER B 1 37  ? -39.030 -51.369 11.592  1.00 69.27  ? 37  SER B O   1 
ATOM   3719  C CB  . SER B 1 37  ? -39.832 -53.840 9.840   1.00 63.45  ? 37  SER B CB  1 
ATOM   3720  O OG  . SER B 1 37  ? -39.253 -54.532 10.933  1.00 64.37  ? 37  SER B OG  1 
ATOM   3721  N N   . GLN B 1 38  ? -39.379 -50.672 9.462   1.00 64.25  ? 38  GLN B N   1 
ATOM   3722  C CA  . GLN B 1 38  ? -38.361 -49.639 9.550   1.00 61.88  ? 38  GLN B CA  1 
ATOM   3723  C C   . GLN B 1 38  ? -38.896 -48.374 10.226  1.00 61.66  ? 38  GLN B C   1 
ATOM   3724  O O   . GLN B 1 38  ? -38.144 -47.689 10.906  1.00 66.80  ? 38  GLN B O   1 
ATOM   3725  C CB  . GLN B 1 38  ? -37.858 -49.302 8.148   1.00 62.36  ? 38  GLN B CB  1 
ATOM   3726  C CG  . GLN B 1 38  ? -37.074 -50.419 7.484   1.00 60.15  ? 38  GLN B CG  1 
ATOM   3727  C CD  . GLN B 1 38  ? -36.631 -49.966 6.113   1.00 63.37  ? 38  GLN B CD  1 
ATOM   3728  O OE1 . GLN B 1 38  ? -37.441 -49.649 5.237   1.00 55.14  ? 38  GLN B OE1 1 
ATOM   3729  N NE2 . GLN B 1 38  ? -35.322 -49.912 5.928   1.00 67.14  ? 38  GLN B NE2 1 
ATOM   3730  N N   . ALA B 1 39  ? -40.174 -48.039 10.010  1.00 58.87  ? 39  ALA B N   1 
ATOM   3731  C CA  . ALA B 1 39  ? -40.802 -46.900 10.665  1.00 61.69  ? 39  ALA B CA  1 
ATOM   3732  C C   . ALA B 1 39  ? -40.977 -47.133 12.174  1.00 60.81  ? 39  ALA B C   1 
ATOM   3733  O O   . ALA B 1 39  ? -40.824 -46.207 12.966  1.00 68.72  ? 39  ALA B O   1 
ATOM   3734  C CB  . ALA B 1 39  ? -42.123 -46.595 9.996   1.00 61.29  ? 39  ALA B CB  1 
ATOM   3735  N N   . ILE B 1 40  ? -41.293 -48.369 12.566  1.00 59.41  ? 40  ILE B N   1 
ATOM   3736  C CA  . ILE B 1 40  ? -41.455 -48.741 13.962  1.00 61.24  ? 40  ILE B CA  1 
ATOM   3737  C C   . ILE B 1 40  ? -40.093 -48.973 14.618  1.00 62.49  ? 40  ILE B C   1 
ATOM   3738  O O   . ILE B 1 40  ? -39.947 -48.828 15.836  1.00 59.99  ? 40  ILE B O   1 
ATOM   3739  C CB  . ILE B 1 40  ? -42.347 -49.994 14.063  1.00 62.12  ? 40  ILE B CB  1 
ATOM   3740  C CG1 . ILE B 1 40  ? -43.794 -49.663 13.690  1.00 70.56  ? 40  ILE B CG1 1 
ATOM   3741  C CG2 . ILE B 1 40  ? -42.258 -50.644 15.438  1.00 56.77  ? 40  ILE B CG2 1 
ATOM   3742  C CD1 . ILE B 1 40  ? -44.721 -50.868 13.679  1.00 75.08  ? 40  ILE B CD1 1 
ATOM   3743  N N   . GLY B 1 41  ? -39.103 -49.368 13.811  1.00 61.19  ? 41  GLY B N   1 
ATOM   3744  C CA  . GLY B 1 41  ? -37.802 -49.765 14.328  1.00 62.30  ? 41  GLY B CA  1 
ATOM   3745  C C   . GLY B 1 41  ? -36.732 -48.699 14.104  1.00 59.01  ? 41  GLY B C   1 
ATOM   3746  O O   . GLY B 1 41  ? -35.584 -49.025 13.800  1.00 58.83  ? 41  GLY B O   1 
ATOM   3747  N N   . GLY B 1 42  ? -37.113 -47.426 14.269  1.00 59.71  ? 42  GLY B N   1 
ATOM   3748  C CA  . GLY B 1 42  ? -36.157 -46.334 14.355  1.00 63.11  ? 42  GLY B CA  1 
ATOM   3749  C C   . GLY B 1 42  ? -35.400 -46.149 13.045  1.00 65.13  ? 42  GLY B C   1 
ATOM   3750  O O   . GLY B 1 42  ? -34.167 -46.124 13.039  1.00 65.72  ? 42  GLY B O   1 
ATOM   3751  N N   . MET B 1 43  ? -36.176 -46.079 11.951  1.00 63.15  ? 43  MET B N   1 
ATOM   3752  C CA  . MET B 1 43  ? -35.688 -45.782 10.619  1.00 58.34  ? 43  MET B CA  1 
ATOM   3753  C C   . MET B 1 43  ? -34.525 -46.696 10.214  1.00 59.79  ? 43  MET B C   1 
ATOM   3754  O O   . MET B 1 43  ? -33.744 -46.319 9.345   1.00 57.34  ? 43  MET B O   1 
ATOM   3755  C CB  . MET B 1 43  ? -35.201 -44.334 10.574  1.00 67.54  ? 43  MET B CB  1 
ATOM   3756  C CG  . MET B 1 43  ? -36.287 -43.299 10.803  1.00 75.39  ? 43  MET B CG  1 
ATOM   3757  S SD  . MET B 1 43  ? -35.610 -41.607 10.706  1.00 77.10  ? 43  MET B SD  1 
ATOM   3758  C CE  . MET B 1 43  ? -37.025 -40.611 11.170  1.00 73.81  ? 43  MET B CE  1 
ATOM   3759  N N   . ARG B 1 44  ? -34.406 -47.899 10.798  1.00 56.56  ? 44  ARG B N   1 
ATOM   3760  C CA  . ARG B 1 44  ? -33.190 -48.677 10.631  1.00 62.10  ? 44  ARG B CA  1 
ATOM   3761  C C   . ARG B 1 44  ? -33.022 -49.026 9.159   1.00 66.13  ? 44  ARG B C   1 
ATOM   3762  O O   . ARG B 1 44  ? -33.917 -49.625 8.566   1.00 64.33  ? 44  ARG B O   1 
ATOM   3763  C CB  . ARG B 1 44  ? -33.238 -49.957 11.467  1.00 72.18  ? 44  ARG B CB  1 
ATOM   3764  C CG  . ARG B 1 44  ? -31.968 -50.805 11.485  1.00 77.95  ? 44  ARG B CG  1 
ATOM   3765  C CD  . ARG B 1 44  ? -32.221 -52.036 12.358  1.00 95.94  ? 44  ARG B CD  1 
ATOM   3766  N NE  . ARG B 1 44  ? -33.523 -52.698 12.125  1.00 101.77 ? 44  ARG B NE  1 
ATOM   3767  C CZ  . ARG B 1 44  ? -34.619 -52.608 12.902  1.00 99.09  ? 44  ARG B CZ  1 
ATOM   3768  N NH1 . ARG B 1 44  ? -34.535 -52.510 14.222  1.00 87.53  ? 44  ARG B NH1 1 
ATOM   3769  N NH2 . ARG B 1 44  ? -35.821 -52.648 12.346  1.00 87.73  ? 44  ARG B NH2 1 
ATOM   3770  N N   . GLY B 1 45  ? -31.879 -48.626 8.588   1.00 67.68  ? 45  GLY B N   1 
ATOM   3771  C CA  . GLY B 1 45  ? -31.525 -48.966 7.220   1.00 64.91  ? 45  GLY B CA  1 
ATOM   3772  C C   . GLY B 1 45  ? -31.937 -47.909 6.193   1.00 68.45  ? 45  GLY B C   1 
ATOM   3773  O O   . GLY B 1 45  ? -31.498 -48.002 5.047   1.00 77.80  ? 45  GLY B O   1 
ATOM   3774  N N   . ILE B 1 46  ? -32.756 -46.912 6.576   1.00 66.27  ? 46  ILE B N   1 
ATOM   3775  C CA  . ILE B 1 46  ? -33.267 -45.970 5.587   1.00 67.10  ? 46  ILE B CA  1 
ATOM   3776  C C   . ILE B 1 46  ? -32.173 -44.989 5.180   1.00 65.33  ? 46  ILE B C   1 
ATOM   3777  O O   . ILE B 1 46  ? -31.607 -44.325 6.039   1.00 63.30  ? 46  ILE B O   1 
ATOM   3778  C CB  . ILE B 1 46  ? -34.478 -45.165 6.079   1.00 70.02  ? 46  ILE B CB  1 
ATOM   3779  C CG1 . ILE B 1 46  ? -35.655 -46.039 6.510   1.00 84.79  ? 46  ILE B CG1 1 
ATOM   3780  C CG2 . ILE B 1 46  ? -34.890 -44.178 4.996   1.00 69.82  ? 46  ILE B CG2 1 
ATOM   3781  C CD1 . ILE B 1 46  ? -36.771 -45.254 7.206   1.00 92.61  ? 46  ILE B CD1 1 
ATOM   3782  N N   . LYS B 1 47  ? -31.957 -44.864 3.863   1.00 65.63  ? 47  LYS B N   1 
ATOM   3783  C CA  . LYS B 1 47  ? -30.997 -43.938 3.284   1.00 63.28  ? 47  LYS B CA  1 
ATOM   3784  C C   . LYS B 1 47  ? -31.680 -42.591 3.130   1.00 60.62  ? 47  LYS B C   1 
ATOM   3785  O O   . LYS B 1 47  ? -32.321 -42.355 2.109   1.00 56.50  ? 47  LYS B O   1 
ATOM   3786  C CB  . LYS B 1 47  ? -30.452 -44.487 1.958   1.00 70.25  ? 47  LYS B CB  1 
ATOM   3787  C CG  . LYS B 1 47  ? -29.396 -45.570 2.176   1.00 85.66  ? 47  LYS B CG  1 
ATOM   3788  C CD  . LYS B 1 47  ? -29.331 -46.758 1.225   1.00 93.42  ? 47  LYS B CD  1 
ATOM   3789  C CE  . LYS B 1 47  ? -28.953 -48.013 1.995   1.00 98.98  ? 47  LYS B CE  1 
ATOM   3790  N NZ  . LYS B 1 47  ? -28.618 -49.150 1.112   1.00 98.89  ? 47  LYS B NZ  1 
ATOM   3791  N N   . SER B 1 48  ? -31.510 -41.740 4.155   1.00 59.51  ? 48  SER B N   1 
ATOM   3792  C CA  . SER B 1 48  ? -32.307 -40.531 4.332   1.00 66.07  ? 48  SER B CA  1 
ATOM   3793  C C   . SER B 1 48  ? -31.455 -39.301 4.686   1.00 66.28  ? 48  SER B C   1 
ATOM   3794  O O   . SER B 1 48  ? -31.979 -38.183 4.770   1.00 65.60  ? 48  SER B O   1 
ATOM   3795  C CB  . SER B 1 48  ? -33.395 -40.778 5.374   1.00 67.92  ? 48  SER B CB  1 
ATOM   3796  O OG  . SER B 1 48  ? -32.915 -41.552 6.476   1.00 67.23  ? 48  SER B OG  1 
ATOM   3797  N N   . LEU B 1 49  ? -30.137 -39.498 4.838   1.00 64.29  ? 49  LEU B N   1 
ATOM   3798  C CA  . LEU B 1 49  ? -29.225 -38.438 5.242   1.00 60.95  ? 49  LEU B CA  1 
ATOM   3799  C C   . LEU B 1 49  ? -28.053 -38.356 4.273   1.00 64.18  ? 49  LEU B C   1 
ATOM   3800  O O   . LEU B 1 49  ? -27.550 -39.384 3.832   1.00 72.17  ? 49  LEU B O   1 
ATOM   3801  C CB  . LEU B 1 49  ? -28.684 -38.761 6.631   1.00 58.64  ? 49  LEU B CB  1 
ATOM   3802  C CG  . LEU B 1 49  ? -29.677 -38.635 7.779   1.00 64.43  ? 49  LEU B CG  1 
ATOM   3803  C CD1 . LEU B 1 49  ? -29.075 -39.250 9.048   1.00 65.31  ? 49  LEU B CD1 1 
ATOM   3804  C CD2 . LEU B 1 49  ? -30.071 -37.174 7.996   1.00 60.23  ? 49  LEU B CD2 1 
ATOM   3805  N N   . VAL B 1 50  ? -27.564 -37.132 4.042   1.00 67.34  ? 50  VAL B N   1 
ATOM   3806  C CA  . VAL B 1 50  ? -26.396 -36.915 3.205   1.00 73.29  ? 50  VAL B CA  1 
ATOM   3807  C C   . VAL B 1 50  ? -25.254 -36.304 4.031   1.00 76.38  ? 50  VAL B C   1 
ATOM   3808  O O   . VAL B 1 50  ? -25.435 -35.241 4.623   1.00 78.09  ? 50  VAL B O   1 
ATOM   3809  C CB  . VAL B 1 50  ? -26.761 -36.036 1.993   1.00 71.00  ? 50  VAL B CB  1 
ATOM   3810  C CG1 . VAL B 1 50  ? -25.756 -36.223 0.860   1.00 65.26  ? 50  VAL B CG1 1 
ATOM   3811  C CG2 . VAL B 1 50  ? -28.180 -36.297 1.507   1.00 71.81  ? 50  VAL B CG2 1 
ATOM   3812  N N   . THR B 1 51  ? -24.093 -36.992 4.053   1.00 76.96  ? 51  THR B N   1 
ATOM   3813  C CA  . THR B 1 51  ? -22.850 -36.513 4.659   1.00 75.57  ? 51  THR B CA  1 
ATOM   3814  C C   . THR B 1 51  ? -21.658 -36.917 3.785   1.00 79.06  ? 51  THR B C   1 
ATOM   3815  O O   . THR B 1 51  ? -21.642 -38.042 3.283   1.00 73.09  ? 51  THR B O   1 
ATOM   3816  C CB  . THR B 1 51  ? -22.614 -37.110 6.061   1.00 77.87  ? 51  THR B CB  1 
ATOM   3817  O OG1 . THR B 1 51  ? -21.443 -36.552 6.674   1.00 70.54  ? 51  THR B OG1 1 
ATOM   3818  C CG2 . THR B 1 51  ? -22.477 -38.622 6.050   1.00 76.48  ? 51  THR B CG2 1 
ATOM   3819  N N   . ASP B 1 52  ? -20.625 -36.056 3.708   1.00 78.53  ? 52  ASP B N   1 
ATOM   3820  C CA  . ASP B 1 52  ? -19.409 -36.360 2.955   1.00 76.61  ? 52  ASP B CA  1 
ATOM   3821  C C   . ASP B 1 52  ? -18.198 -36.518 3.884   1.00 72.23  ? 52  ASP B C   1 
ATOM   3822  O O   . ASP B 1 52  ? -17.122 -36.934 3.437   1.00 66.35  ? 52  ASP B O   1 
ATOM   3823  C CB  . ASP B 1 52  ? -19.207 -35.321 1.848   1.00 79.36  ? 52  ASP B CB  1 
ATOM   3824  C CG  . ASP B 1 52  ? -20.378 -35.301 0.880   1.00 86.77  ? 52  ASP B CG  1 
ATOM   3825  O OD1 . ASP B 1 52  ? -20.494 -36.275 0.115   1.00 90.06  ? 52  ASP B OD1 1 
ATOM   3826  O OD2 . ASP B 1 52  ? -21.209 -34.357 0.953   1.00 89.29  ? 52  ASP B OD2 1 
ATOM   3827  N N   . ILE B 1 53  ? -18.384 -36.259 5.191   1.00 60.40  ? 53  ILE B N   1 
ATOM   3828  C CA  . ILE B 1 53  ? -17.263 -36.231 6.115   1.00 52.77  ? 53  ILE B CA  1 
ATOM   3829  C C   . ILE B 1 53  ? -16.729 -37.646 6.296   1.00 51.45  ? 53  ILE B C   1 
ATOM   3830  O O   . ILE B 1 53  ? -15.527 -37.866 6.349   1.00 49.80  ? 53  ILE B O   1 
ATOM   3831  C CB  . ILE B 1 53  ? -17.633 -35.578 7.465   1.00 51.09  ? 53  ILE B CB  1 
ATOM   3832  C CG1 . ILE B 1 53  ? -18.306 -34.215 7.296   1.00 49.18  ? 53  ILE B CG1 1 
ATOM   3833  C CG2 . ILE B 1 53  ? -16.405 -35.452 8.359   1.00 56.35  ? 53  ILE B CG2 1 
ATOM   3834  C CD1 . ILE B 1 53  ? -17.387 -33.142 6.803   1.00 53.15  ? 53  ILE B CD1 1 
ATOM   3835  N N   . SER B 1 54  ? -17.634 -38.610 6.436   1.00 59.42  ? 54  SER B N   1 
ATOM   3836  C CA  . SER B 1 54  ? -17.239 -39.996 6.626   1.00 57.55  ? 54  SER B CA  1 
ATOM   3837  C C   . SER B 1 54  ? -18.342 -40.899 6.092   1.00 54.98  ? 54  SER B C   1 
ATOM   3838  O O   . SER B 1 54  ? -19.486 -40.472 5.935   1.00 49.87  ? 54  SER B O   1 
ATOM   3839  C CB  . SER B 1 54  ? -16.870 -40.303 8.072   1.00 58.74  ? 54  SER B CB  1 
ATOM   3840  O OG  . SER B 1 54  ? -17.996 -40.372 8.943   1.00 60.67  ? 54  SER B OG  1 
ATOM   3841  N N   . TYR B 1 55  ? -17.943 -42.116 5.722   1.00 62.00  ? 55  TYR B N   1 
ATOM   3842  C CA  . TYR B 1 55  ? -18.878 -43.113 5.236   1.00 67.97  ? 55  TYR B CA  1 
ATOM   3843  C C   . TYR B 1 55  ? -18.561 -44.442 5.906   1.00 65.78  ? 55  TYR B C   1 
ATOM   3844  O O   . TYR B 1 55  ? -17.398 -44.833 5.998   1.00 71.07  ? 55  TYR B O   1 
ATOM   3845  C CB  . TYR B 1 55  ? -18.853 -43.272 3.712   1.00 68.99  ? 55  TYR B CB  1 
ATOM   3846  C CG  . TYR B 1 55  ? -19.900 -44.252 3.243   1.00 78.92  ? 55  TYR B CG  1 
ATOM   3847  C CD1 . TYR B 1 55  ? -21.250 -43.967 3.413   1.00 84.15  ? 55  TYR B CD1 1 
ATOM   3848  C CD2 . TYR B 1 55  ? -19.557 -45.503 2.738   1.00 85.72  ? 55  TYR B CD2 1 
ATOM   3849  C CE1 . TYR B 1 55  ? -22.233 -44.869 3.035   1.00 90.67  ? 55  TYR B CE1 1 
ATOM   3850  C CE2 . TYR B 1 55  ? -20.529 -46.424 2.371   1.00 88.58  ? 55  TYR B CE2 1 
ATOM   3851  C CZ  . TYR B 1 55  ? -21.871 -46.098 2.504   1.00 88.36  ? 55  TYR B CZ  1 
ATOM   3852  O OH  . TYR B 1 55  ? -22.860 -46.977 2.133   1.00 81.27  ? 55  TYR B OH  1 
ATOM   3853  N N   . LEU B 1 56  ? -19.622 -45.084 6.396   1.00 71.43  ? 56  LEU B N   1 
ATOM   3854  C CA  . LEU B 1 56  ? -19.537 -46.386 7.024   1.00 87.97  ? 56  LEU B CA  1 
ATOM   3855  C C   . LEU B 1 56  ? -20.029 -47.426 6.022   1.00 101.87 ? 56  LEU B C   1 
ATOM   3856  O O   . LEU B 1 56  ? -21.215 -47.476 5.696   1.00 108.35 ? 56  LEU B O   1 
ATOM   3857  C CB  . LEU B 1 56  ? -20.373 -46.368 8.311   1.00 86.55  ? 56  LEU B CB  1 
ATOM   3858  C CG  . LEU B 1 56  ? -20.472 -47.692 9.071   1.00 85.58  ? 56  LEU B CG  1 
ATOM   3859  C CD1 . LEU B 1 56  ? -19.098 -48.234 9.441   1.00 85.08  ? 56  LEU B CD1 1 
ATOM   3860  C CD2 . LEU B 1 56  ? -21.321 -47.516 10.320  1.00 90.80  ? 56  LEU B CD2 1 
ATOM   3861  N N   . ASP B 1 57  ? -19.078 -48.192 5.476   1.00 109.73 ? 57  ASP B N   1 
ATOM   3862  C CA  . ASP B 1 57  ? -19.375 -49.414 4.744   1.00 107.17 ? 57  ASP B CA  1 
ATOM   3863  C C   . ASP B 1 57  ? -19.609 -50.515 5.790   1.00 120.87 ? 57  ASP B C   1 
ATOM   3864  O O   . ASP B 1 57  ? -18.767 -50.663 6.677   1.00 152.47 ? 57  ASP B O   1 
ATOM   3865  C CB  . ASP B 1 57  ? -18.220 -49.712 3.777   1.00 96.20  ? 57  ASP B CB  1 
ATOM   3866  C CG  . ASP B 1 57  ? -18.329 -51.040 3.046   1.00 92.26  ? 57  ASP B CG  1 
ATOM   3867  O OD1 . ASP B 1 57  ? -19.316 -51.219 2.317   1.00 93.79  ? 57  ASP B OD1 1 
ATOM   3868  O OD2 . ASP B 1 57  ? -17.440 -51.895 3.232   1.00 81.46  ? 57  ASP B OD2 1 
ATOM   3869  N N   . PRO B 1 58  ? -20.741 -51.282 5.781   1.00 108.13 ? 58  PRO B N   1 
ATOM   3870  C CA  . PRO B 1 58  ? -20.926 -52.411 6.719   1.00 100.46 ? 58  PRO B CA  1 
ATOM   3871  C C   . PRO B 1 58  ? -19.769 -53.419 6.874   1.00 101.10 ? 58  PRO B C   1 
ATOM   3872  O O   . PRO B 1 58  ? -19.645 -54.089 7.914   1.00 73.42  ? 58  PRO B O   1 
ATOM   3873  C CB  . PRO B 1 58  ? -22.208 -53.083 6.184   1.00 90.54  ? 58  PRO B CB  1 
ATOM   3874  C CG  . PRO B 1 58  ? -22.999 -51.933 5.594   1.00 89.44  ? 58  PRO B CG  1 
ATOM   3875  C CD  . PRO B 1 58  ? -21.946 -51.041 4.961   1.00 94.34  ? 58  PRO B CD  1 
ATOM   3876  N N   . GLU B 1 59  ? -18.886 -53.474 5.854   1.00 109.89 ? 59  GLU B N   1 
ATOM   3877  C CA  . GLU B 1 59  ? -17.852 -54.489 5.722   1.00 104.67 ? 59  GLU B CA  1 
ATOM   3878  C C   . GLU B 1 59  ? -16.451 -53.946 6.021   1.00 104.99 ? 59  GLU B C   1 
ATOM   3879  O O   . GLU B 1 59  ? -15.812 -54.431 6.953   1.00 103.79 ? 59  GLU B O   1 
ATOM   3880  C CB  . GLU B 1 59  ? -17.949 -55.069 4.314   1.00 111.33 ? 59  GLU B CB  1 
ATOM   3881  C CG  . GLU B 1 59  ? -19.239 -55.849 4.098   1.00 117.65 ? 59  GLU B CG  1 
ATOM   3882  C CD  . GLU B 1 59  ? -19.201 -57.299 4.558   1.00 119.09 ? 59  GLU B CD  1 
ATOM   3883  O OE1 . GLU B 1 59  ? -18.288 -58.038 4.107   1.00 103.98 ? 59  GLU B OE1 1 
ATOM   3884  O OE2 . GLU B 1 59  ? -20.085 -57.707 5.352   1.00 116.23 ? 59  GLU B OE2 1 
ATOM   3885  N N   . GLU B 1 60  ? -15.954 -52.984 5.220   1.00 109.05 ? 60  GLU B N   1 
ATOM   3886  C CA  . GLU B 1 60  ? -14.585 -52.480 5.369   1.00 110.03 ? 60  GLU B CA  1 
ATOM   3887  C C   . GLU B 1 60  ? -14.457 -51.634 6.641   1.00 97.94  ? 60  GLU B C   1 
ATOM   3888  O O   . GLU B 1 60  ? -13.397 -51.600 7.267   1.00 83.79  ? 60  GLU B O   1 
ATOM   3889  C CB  . GLU B 1 60  ? -14.121 -51.616 4.182   1.00 108.73 ? 60  GLU B CB  1 
ATOM   3890  C CG  . GLU B 1 60  ? -14.345 -52.209 2.790   1.00 103.09 ? 60  GLU B CG  1 
ATOM   3891  C CD  . GLU B 1 60  ? -14.014 -53.686 2.606   1.00 99.56  ? 60  GLU B CD  1 
ATOM   3892  O OE1 . GLU B 1 60  ? -12.966 -54.123 3.098   1.00 97.08  ? 60  GLU B OE1 1 
ATOM   3893  O OE2 . GLU B 1 60  ? -14.795 -54.400 1.946   1.00 95.43  ? 60  GLU B OE2 1 
ATOM   3894  N N   . GLY B 1 61  ? -15.546 -50.934 6.987   1.00 100.41 ? 61  GLY B N   1 
ATOM   3895  C CA  . GLY B 1 61  ? -15.601 -50.047 8.140   1.00 98.01  ? 61  GLY B CA  1 
ATOM   3896  C C   . GLY B 1 61  ? -15.755 -48.574 7.749   1.00 86.06  ? 61  GLY B C   1 
ATOM   3897  O O   . GLY B 1 61  ? -16.348 -48.244 6.714   1.00 81.12  ? 61  GLY B O   1 
ATOM   3898  N N   . ILE B 1 62  ? -15.209 -47.703 8.613   1.00 70.62  ? 62  ILE B N   1 
ATOM   3899  C CA  . ILE B 1 62  ? -15.310 -46.256 8.456   1.00 64.25  ? 62  ILE B CA  1 
ATOM   3900  C C   . ILE B 1 62  ? -14.175 -45.753 7.539   1.00 56.35  ? 62  ILE B C   1 
ATOM   3901  O O   . ILE B 1 62  ? -13.047 -46.234 7.584   1.00 44.38  ? 62  ILE B O   1 
ATOM   3902  C CB  . ILE B 1 62  ? -15.393 -45.558 9.848   1.00 53.70  ? 62  ILE B CB  1 
ATOM   3903  C CG1 . ILE B 1 62  ? -15.694 -44.057 9.769   1.00 50.83  ? 62  ILE B CG1 1 
ATOM   3904  C CG2 . ILE B 1 62  ? -14.159 -45.810 10.700  1.00 53.99  ? 62  ILE B CG2 1 
ATOM   3905  C CD1 . ILE B 1 62  ? -17.112 -43.737 9.297   1.00 55.09  ? 62  ILE B CD1 1 
ATOM   3906  N N   . ARG B 1 63  ? -14.530 -44.824 6.643   1.00 55.04  ? 63  ARG B N   1 
ATOM   3907  C CA  . ARG B 1 63  ? -13.590 -44.039 5.865   1.00 62.18  ? 63  ARG B CA  1 
ATOM   3908  C C   . ARG B 1 63  ? -13.826 -42.573 6.202   1.00 68.52  ? 63  ARG B C   1 
ATOM   3909  O O   . ARG B 1 63  ? -14.962 -42.119 6.143   1.00 67.88  ? 63  ARG B O   1 
ATOM   3910  C CB  . ARG B 1 63  ? -13.785 -44.186 4.353   1.00 66.53  ? 63  ARG B CB  1 
ATOM   3911  C CG  . ARG B 1 63  ? -13.297 -45.505 3.769   1.00 76.22  ? 63  ARG B CG  1 
ATOM   3912  C CD  . ARG B 1 63  ? -13.104 -45.430 2.254   1.00 88.51  ? 63  ARG B CD  1 
ATOM   3913  N NE  . ARG B 1 63  ? -13.224 -46.755 1.634   1.00 101.14 ? 63  ARG B NE  1 
ATOM   3914  C CZ  . ARG B 1 63  ? -12.435 -47.801 1.900   1.00 106.57 ? 63  ARG B CZ  1 
ATOM   3915  N NH1 . ARG B 1 63  ? -11.120 -47.658 1.812   1.00 87.75  ? 63  ARG B NH1 1 
ATOM   3916  N NH2 . ARG B 1 63  ? -12.962 -48.991 2.197   1.00 104.98 ? 63  ARG B NH2 1 
ATOM   3917  N N   . PHE B 1 64  ? -12.750 -41.856 6.556   1.00 74.75  ? 64  PHE B N   1 
ATOM   3918  C CA  . PHE B 1 64  ? -12.804 -40.418 6.758   1.00 59.71  ? 64  PHE B CA  1 
ATOM   3919  C C   . PHE B 1 64  ? -12.381 -39.721 5.474   1.00 55.11  ? 64  PHE B C   1 
ATOM   3920  O O   . PHE B 1 64  ? -11.208 -39.770 5.127   1.00 63.47  ? 64  PHE B O   1 
ATOM   3921  C CB  . PHE B 1 64  ? -11.881 -40.001 7.901   1.00 56.91  ? 64  PHE B CB  1 
ATOM   3922  C CG  . PHE B 1 64  ? -12.166 -40.705 9.199   1.00 58.63  ? 64  PHE B CG  1 
ATOM   3923  C CD1 . PHE B 1 64  ? -13.401 -40.569 9.817   1.00 52.34  ? 64  PHE B CD1 1 
ATOM   3924  C CD2 . PHE B 1 64  ? -11.209 -41.518 9.792   1.00 58.31  ? 64  PHE B CD2 1 
ATOM   3925  C CE1 . PHE B 1 64  ? -13.656 -41.191 11.029  1.00 54.47  ? 64  PHE B CE1 1 
ATOM   3926  C CE2 . PHE B 1 64  ? -11.464 -42.143 11.005  1.00 57.78  ? 64  PHE B CE2 1 
ATOM   3927  C CZ  . PHE B 1 64  ? -12.695 -41.992 11.614  1.00 54.79  ? 64  PHE B CZ  1 
ATOM   3928  N N   . ARG B 1 65  ? -13.332 -39.076 4.787   1.00 55.49  ? 65  ARG B N   1 
ATOM   3929  C CA  . ARG B 1 65  ? -13.044 -38.346 3.560   1.00 53.61  ? 65  ARG B CA  1 
ATOM   3930  C C   . ARG B 1 65  ? -12.314 -39.246 2.543   1.00 53.89  ? 65  ARG B C   1 
ATOM   3931  O O   . ARG B 1 65  ? -11.376 -38.833 1.871   1.00 46.77  ? 65  ARG B O   1 
ATOM   3932  C CB  . ARG B 1 65  ? -12.219 -37.105 3.916   1.00 51.03  ? 65  ARG B CB  1 
ATOM   3933  C CG  . ARG B 1 65  ? -12.995 -35.974 4.571   1.00 47.08  ? 65  ARG B CG  1 
ATOM   3934  C CD  . ARG B 1 65  ? -13.968 -35.330 3.600   1.00 47.65  ? 65  ARG B CD  1 
ATOM   3935  N NE  . ARG B 1 65  ? -14.480 -34.096 4.160   1.00 46.58  ? 65  ARG B NE  1 
ATOM   3936  C CZ  . ARG B 1 65  ? -15.312 -33.266 3.532   1.00 49.42  ? 65  ARG B CZ  1 
ATOM   3937  N NH1 . ARG B 1 65  ? -15.983 -33.661 2.463   1.00 45.84  ? 65  ARG B NH1 1 
ATOM   3938  N NH2 . ARG B 1 65  ? -15.485 -32.039 4.002   1.00 58.02  ? 65  ARG B NH2 1 
ATOM   3939  N N   . GLY B 1 66  ? -12.730 -40.511 2.460   1.00 59.98  ? 66  GLY B N   1 
ATOM   3940  C CA  . GLY B 1 66  ? -12.175 -41.459 1.511   1.00 56.58  ? 66  GLY B CA  1 
ATOM   3941  C C   . GLY B 1 66  ? -11.057 -42.312 2.098   1.00 56.29  ? 66  GLY B C   1 
ATOM   3942  O O   . GLY B 1 66  ? -10.786 -43.370 1.562   1.00 68.15  ? 66  GLY B O   1 
ATOM   3943  N N   . TYR B 1 67  ? -10.393 -41.874 3.173   1.00 55.24  ? 67  TYR B N   1 
ATOM   3944  C CA  . TYR B 1 67  ? -9.272  -42.631 3.710   1.00 63.38  ? 67  TYR B CA  1 
ATOM   3945  C C   . TYR B 1 67  ? -9.699  -43.636 4.786   1.00 67.27  ? 67  TYR B C   1 
ATOM   3946  O O   . TYR B 1 67  ? -10.519 -43.329 5.643   1.00 75.56  ? 67  TYR B O   1 
ATOM   3947  C CB  . TYR B 1 67  ? -8.239  -41.676 4.307   1.00 67.54  ? 67  TYR B CB  1 
ATOM   3948  C CG  . TYR B 1 67  ? -7.665  -40.678 3.335   1.00 70.56  ? 67  TYR B CG  1 
ATOM   3949  C CD1 . TYR B 1 67  ? -6.583  -41.002 2.528   1.00 77.00  ? 67  TYR B CD1 1 
ATOM   3950  C CD2 . TYR B 1 67  ? -8.217  -39.414 3.207   1.00 72.79  ? 67  TYR B CD2 1 
ATOM   3951  C CE1 . TYR B 1 67  ? -6.059  -40.091 1.624   1.00 75.22  ? 67  TYR B CE1 1 
ATOM   3952  C CE2 . TYR B 1 67  ? -7.703  -38.487 2.312   1.00 73.63  ? 67  TYR B CE2 1 
ATOM   3953  C CZ  . TYR B 1 67  ? -6.621  -38.831 1.515   1.00 70.03  ? 67  TYR B CZ  1 
ATOM   3954  O OH  . TYR B 1 67  ? -6.093  -37.946 0.618   1.00 60.72  ? 67  TYR B OH  1 
ATOM   3955  N N   . THR B 1 68  ? -9.089  -44.827 4.778   1.00 68.65  ? 68  THR B N   1 
ATOM   3956  C CA  . THR B 1 68  ? -9.206  -45.767 5.888   1.00 71.12  ? 68  THR B CA  1 
ATOM   3957  C C   . THR B 1 68  ? -8.426  -45.238 7.089   1.00 68.80  ? 68  THR B C   1 
ATOM   3958  O O   . THR B 1 68  ? -7.611  -44.325 6.980   1.00 68.59  ? 68  THR B O   1 
ATOM   3959  C CB  . THR B 1 68  ? -8.699  -47.184 5.555   1.00 69.13  ? 68  THR B CB  1 
ATOM   3960  O OG1 . THR B 1 68  ? -7.274  -47.195 5.482   1.00 63.39  ? 68  THR B OG1 1 
ATOM   3961  C CG2 . THR B 1 68  ? -9.257  -47.733 4.262   1.00 72.60  ? 68  THR B CG2 1 
ATOM   3962  N N   . ILE B 1 69  ? -8.679  -45.846 8.242   1.00 69.29  ? 69  ILE B N   1 
ATOM   3963  C CA  . ILE B 1 69  ? -8.029  -45.438 9.472   1.00 65.54  ? 69  ILE B CA  1 
ATOM   3964  C C   . ILE B 1 69  ? -6.525  -45.647 9.322   1.00 67.15  ? 69  ILE B C   1 
ATOM   3965  O O   . ILE B 1 69  ? -5.758  -44.717 9.570   1.00 77.96  ? 69  ILE B O   1 
ATOM   3966  C CB  . ILE B 1 69  ? -8.663  -46.180 10.666  1.00 70.82  ? 69  ILE B CB  1 
ATOM   3967  C CG1 . ILE B 1 69  ? -10.004 -45.541 11.030  1.00 76.78  ? 69  ILE B CG1 1 
ATOM   3968  C CG2 . ILE B 1 69  ? -7.736  -46.260 11.872  1.00 71.51  ? 69  ILE B CG2 1 
ATOM   3969  C CD1 . ILE B 1 69  ? -10.949 -46.483 11.719  1.00 76.19  ? 69  ILE B CD1 1 
ATOM   3970  N N   . PRO B 1 70  ? -6.036  -46.836 8.894   1.00 66.12  ? 70  PRO B N   1 
ATOM   3971  C CA  . PRO B 1 70  ? -4.596  -47.043 8.778   1.00 64.75  ? 70  PRO B CA  1 
ATOM   3972  C C   . PRO B 1 70  ? -3.978  -45.989 7.854   1.00 63.36  ? 70  PRO B C   1 
ATOM   3973  O O   . PRO B 1 70  ? -2.857  -45.548 8.097   1.00 63.51  ? 70  PRO B O   1 
ATOM   3974  C CB  . PRO B 1 70  ? -4.476  -48.492 8.266   1.00 66.76  ? 70  PRO B CB  1 
ATOM   3975  C CG  . PRO B 1 70  ? -5.788  -49.149 8.647   1.00 62.22  ? 70  PRO B CG  1 
ATOM   3976  C CD  . PRO B 1 70  ? -6.802  -48.038 8.515   1.00 65.61  ? 70  PRO B CD  1 
ATOM   3977  N N   . GLU B 1 71  ? -4.738  -45.540 6.842   1.00 61.77  ? 71  GLU B N   1 
ATOM   3978  C CA  . GLU B 1 71  ? -4.279  -44.504 5.924   1.00 64.80  ? 71  GLU B CA  1 
ATOM   3979  C C   . GLU B 1 71  ? -4.187  -43.158 6.648   1.00 70.71  ? 71  GLU B C   1 
ATOM   3980  O O   . GLU B 1 71  ? -3.216  -42.422 6.494   1.00 71.26  ? 71  GLU B O   1 
ATOM   3981  C CB  . GLU B 1 71  ? -5.199  -44.366 4.702   1.00 70.25  ? 71  GLU B CB  1 
ATOM   3982  C CG  . GLU B 1 71  ? -5.123  -45.526 3.710   1.00 77.23  ? 71  GLU B CG  1 
ATOM   3983  C CD  . GLU B 1 71  ? -6.122  -45.579 2.551   1.00 78.33  ? 71  GLU B CD  1 
ATOM   3984  O OE1 . GLU B 1 71  ? -6.882  -44.620 2.325   1.00 68.67  ? 71  GLU B OE1 1 
ATOM   3985  O OE2 . GLU B 1 71  ? -6.135  -46.601 1.851   1.00 89.08  ? 71  GLU B OE2 1 
ATOM   3986  N N   . VAL B 1 72  ? -5.209  -42.823 7.441   1.00 75.49  ? 72  VAL B N   1 
ATOM   3987  C CA  . VAL B 1 72  ? -5.240  -41.540 8.122   1.00 71.66  ? 72  VAL B CA  1 
ATOM   3988  C C   . VAL B 1 72  ? -4.078  -41.446 9.118   1.00 71.92  ? 72  VAL B C   1 
ATOM   3989  O O   . VAL B 1 72  ? -3.376  -40.433 9.176   1.00 65.21  ? 72  VAL B O   1 
ATOM   3990  C CB  . VAL B 1 72  ? -6.608  -41.332 8.795   1.00 74.01  ? 72  VAL B CB  1 
ATOM   3991  C CG1 . VAL B 1 72  ? -6.582  -40.202 9.827   1.00 78.41  ? 72  VAL B CG1 1 
ATOM   3992  C CG2 . VAL B 1 72  ? -7.693  -41.109 7.744   1.00 69.76  ? 72  VAL B CG2 1 
ATOM   3993  N N   . LEU B 1 73  ? -3.862  -42.505 9.904   1.00 62.53  ? 73  LEU B N   1 
ATOM   3994  C CA  . LEU B 1 73  ? -2.770  -42.498 10.861  1.00 64.37  ? 73  LEU B CA  1 
ATOM   3995  C C   . LEU B 1 73  ? -1.432  -42.451 10.135  1.00 68.71  ? 73  LEU B C   1 
ATOM   3996  O O   . LEU B 1 73  ? -0.500  -41.822 10.626  1.00 63.59  ? 73  LEU B O   1 
ATOM   3997  C CB  . LEU B 1 73  ? -2.866  -43.746 11.737  1.00 62.89  ? 73  LEU B CB  1 
ATOM   3998  C CG  . LEU B 1 73  ? -4.130  -43.836 12.590  1.00 67.53  ? 73  LEU B CG  1 
ATOM   3999  C CD1 . LEU B 1 73  ? -4.054  -45.004 13.552  1.00 71.03  ? 73  LEU B CD1 1 
ATOM   4000  C CD2 . LEU B 1 73  ? -4.347  -42.560 13.371  1.00 69.64  ? 73  LEU B CD2 1 
ATOM   4001  N N   . GLU B 1 74  ? -1.362  -43.140 8.990   1.00 72.44  ? 74  GLU B N   1 
ATOM   4002  C CA  . GLU B 1 74  ? -0.206  -43.142 8.107   1.00 77.48  ? 74  GLU B CA  1 
ATOM   4003  C C   . GLU B 1 74  ? 0.155   -41.717 7.657   1.00 65.07  ? 74  GLU B C   1 
ATOM   4004  O O   . GLU B 1 74  ? 1.283   -41.295 7.849   1.00 58.14  ? 74  GLU B O   1 
ATOM   4005  C CB  . GLU B 1 74  ? -0.502  -44.132 6.967   1.00 92.33  ? 74  GLU B CB  1 
ATOM   4006  C CG  . GLU B 1 74  ? 0.221   -43.903 5.647   1.00 99.60  ? 74  GLU B CG  1 
ATOM   4007  C CD  . GLU B 1 74  ? 1.629   -44.467 5.534   1.00 107.21 ? 74  GLU B CD  1 
ATOM   4008  O OE1 . GLU B 1 74  ? 2.322   -44.594 6.578   1.00 107.91 ? 74  GLU B OE1 1 
ATOM   4009  O OE2 . GLU B 1 74  ? 2.026   -44.765 4.401   1.00 113.75 ? 74  GLU B OE2 1 
ATOM   4010  N N   . LYS B 1 75  ? -0.798  -40.965 7.090   1.00 62.76  ? 75  LYS B N   1 
ATOM   4011  C CA  . LYS B 1 75  ? -0.499  -39.771 6.301   1.00 64.35  ? 75  LYS B CA  1 
ATOM   4012  C C   . LYS B 1 75  ? -0.556  -38.461 7.089   1.00 68.99  ? 75  LYS B C   1 
ATOM   4013  O O   . LYS B 1 75  ? -0.009  -37.464 6.625   1.00 68.20  ? 75  LYS B O   1 
ATOM   4014  C CB  . LYS B 1 75  ? -1.520  -39.595 5.175   1.00 65.62  ? 75  LYS B CB  1 
ATOM   4015  C CG  . LYS B 1 75  ? -1.596  -40.757 4.201   1.00 73.00  ? 75  LYS B CG  1 
ATOM   4016  C CD  . LYS B 1 75  ? -2.726  -40.630 3.206   1.00 78.45  ? 75  LYS B CD  1 
ATOM   4017  C CE  . LYS B 1 75  ? -2.971  -41.895 2.412   1.00 82.11  ? 75  LYS B CE  1 
ATOM   4018  N NZ  . LYS B 1 75  ? -1.704  -42.531 1.978   1.00 82.67  ? 75  LYS B NZ  1 
ATOM   4019  N N   . LEU B 1 76  ? -1.299  -38.421 8.205   1.00 70.05  ? 76  LEU B N   1 
ATOM   4020  C CA  . LEU B 1 76  ? -1.426  -37.192 8.973   1.00 69.12  ? 76  LEU B CA  1 
ATOM   4021  C C   . LEU B 1 76  ? -0.078  -36.848 9.621   1.00 69.90  ? 76  LEU B C   1 
ATOM   4022  O O   . LEU B 1 76  ? 0.591   -37.733 10.161  1.00 60.21  ? 76  LEU B O   1 
ATOM   4023  C CB  . LEU B 1 76  ? -2.515  -37.350 10.044  1.00 71.25  ? 76  LEU B CB  1 
ATOM   4024  C CG  . LEU B 1 76  ? -3.979  -37.222 9.604   1.00 69.87  ? 76  LEU B CG  1 
ATOM   4025  C CD1 . LEU B 1 76  ? -4.893  -37.502 10.794  1.00 66.53  ? 76  LEU B CD1 1 
ATOM   4026  C CD2 . LEU B 1 76  ? -4.298  -35.848 8.990   1.00 62.45  ? 76  LEU B CD2 1 
ATOM   4027  N N   . PRO B 1 77  ? 0.346   -35.554 9.608   1.00 57.55  ? 77  PRO B N   1 
ATOM   4028  C CA  . PRO B 1 77  ? 1.523   -35.091 10.350  1.00 57.39  ? 77  PRO B CA  1 
ATOM   4029  C C   . PRO B 1 77  ? 1.576   -35.494 11.823  1.00 61.98  ? 77  PRO B C   1 
ATOM   4030  O O   . PRO B 1 77  ? 0.628   -35.245 12.561  1.00 68.54  ? 77  PRO B O   1 
ATOM   4031  C CB  . PRO B 1 77  ? 1.406   -33.557 10.293  1.00 49.81  ? 77  PRO B CB  1 
ATOM   4032  C CG  . PRO B 1 77  ? 0.659   -33.305 9.024   1.00 50.76  ? 77  PRO B CG  1 
ATOM   4033  C CD  . PRO B 1 77  ? -0.314  -34.452 8.897   1.00 51.92  ? 77  PRO B CD  1 
ATOM   4034  N N   . LYS B 1 78  ? 2.710   -36.070 12.236  1.00 69.58  ? 78  LYS B N   1 
ATOM   4035  C CA  . LYS B 1 78  ? 2.908   -36.555 13.594  1.00 75.86  ? 78  LYS B CA  1 
ATOM   4036  C C   . LYS B 1 78  ? 3.404   -35.430 14.503  1.00 81.99  ? 78  LYS B C   1 
ATOM   4037  O O   . LYS B 1 78  ? 3.986   -34.449 14.047  1.00 83.38  ? 78  LYS B O   1 
ATOM   4038  C CB  . LYS B 1 78  ? 3.936   -37.688 13.609  1.00 73.11  ? 78  LYS B CB  1 
ATOM   4039  C CG  . LYS B 1 78  ? 3.673   -38.826 12.636  1.00 72.80  ? 78  LYS B CG  1 
ATOM   4040  C CD  . LYS B 1 78  ? 2.677   -39.825 13.128  1.00 71.43  ? 78  LYS B CD  1 
ATOM   4041  C CE  . LYS B 1 78  ? 2.216   -40.765 12.039  1.00 76.81  ? 78  LYS B CE  1 
ATOM   4042  N NZ  . LYS B 1 78  ? 1.506   -40.031 10.970  1.00 80.92  ? 78  LYS B NZ  1 
ATOM   4043  N N   . VAL B 1 79  ? 3.182   -35.600 15.814  1.00 91.05  ? 79  VAL B N   1 
ATOM   4044  C CA  . VAL B 1 79  ? 3.688   -34.664 16.804  1.00 96.87  ? 79  VAL B CA  1 
ATOM   4045  C C   . VAL B 1 79  ? 5.164   -34.993 17.048  1.00 100.14 ? 79  VAL B C   1 
ATOM   4046  O O   . VAL B 1 79  ? 5.525   -36.156 17.237  1.00 97.94  ? 79  VAL B O   1 
ATOM   4047  C CB  . VAL B 1 79  ? 2.847   -34.685 18.099  1.00 94.98  ? 79  VAL B CB  1 
ATOM   4048  C CG1 . VAL B 1 79  ? 3.368   -33.689 19.129  1.00 97.39  ? 79  VAL B CG1 1 
ATOM   4049  C CG2 . VAL B 1 79  ? 1.378   -34.415 17.804  1.00 93.16  ? 79  VAL B CG2 1 
ATOM   4050  N N   . PRO B 1 80  ? 6.074   -33.986 17.021  1.00 87.70  ? 80  PRO B N   1 
ATOM   4051  C CA  . PRO B 1 80  ? 7.475   -34.217 17.371  1.00 85.15  ? 80  PRO B CA  1 
ATOM   4052  C C   . PRO B 1 80  ? 7.622   -34.794 18.783  1.00 79.55  ? 80  PRO B C   1 
ATOM   4053  O O   . PRO B 1 80  ? 7.076   -34.254 19.745  1.00 79.13  ? 80  PRO B O   1 
ATOM   4054  C CB  . PRO B 1 80  ? 8.123   -32.824 17.268  1.00 88.85  ? 80  PRO B CB  1 
ATOM   4055  C CG  . PRO B 1 80  ? 7.173   -32.002 16.420  1.00 89.05  ? 80  PRO B CG  1 
ATOM   4056  C CD  . PRO B 1 80  ? 5.801   -32.585 16.662  1.00 85.13  ? 80  PRO B CD  1 
ATOM   4057  N N   . GLY B 1 81  ? 8.358   -35.906 18.889  1.00 78.12  ? 81  GLY B N   1 
ATOM   4058  C CA  . GLY B 1 81  ? 8.580   -36.596 20.151  1.00 79.44  ? 81  GLY B CA  1 
ATOM   4059  C C   . GLY B 1 81  ? 7.645   -37.792 20.329  1.00 84.56  ? 81  GLY B C   1 
ATOM   4060  O O   . GLY B 1 81  ? 7.874   -38.621 21.206  1.00 79.41  ? 81  GLY B O   1 
ATOM   4061  N N   . ALA B 1 82  ? 6.623   -37.902 19.460  1.00 92.79  ? 82  ALA B N   1 
ATOM   4062  C CA  . ALA B 1 82  ? 5.431   -38.694 19.736  1.00 89.96  ? 82  ALA B CA  1 
ATOM   4063  C C   . ALA B 1 82  ? 4.962   -39.470 18.501  1.00 81.50  ? 82  ALA B C   1 
ATOM   4064  O O   . ALA B 1 82  ? 5.158   -39.053 17.360  1.00 71.72  ? 82  ALA B O   1 
ATOM   4065  C CB  . ALA B 1 82  ? 4.338   -37.774 20.241  1.00 95.48  ? 82  ALA B CB  1 
ATOM   4066  N N   . GLU B 1 83  ? 4.245   -40.561 18.780  1.00 76.89  ? 83  GLU B N   1 
ATOM   4067  C CA  . GLU B 1 83  ? 3.900   -41.587 17.808  1.00 86.10  ? 83  GLU B CA  1 
ATOM   4068  C C   . GLU B 1 83  ? 2.676   -41.184 16.984  1.00 71.43  ? 83  GLU B C   1 
ATOM   4069  O O   . GLU B 1 83  ? 2.481   -41.676 15.878  1.00 62.50  ? 83  GLU B O   1 
ATOM   4070  C CB  . GLU B 1 83  ? 3.703   -42.901 18.579  1.00 99.60  ? 83  GLU B CB  1 
ATOM   4071  C CG  . GLU B 1 83  ? 3.210   -44.081 17.751  1.00 110.73 ? 83  GLU B CG  1 
ATOM   4072  C CD  . GLU B 1 83  ? 2.970   -45.343 18.573  1.00 120.52 ? 83  GLU B CD  1 
ATOM   4073  O OE1 . GLU B 1 83  ? 2.103   -46.155 18.177  1.00 107.66 ? 83  GLU B OE1 1 
ATOM   4074  O OE2 . GLU B 1 83  ? 3.651   -45.518 19.615  1.00 136.48 ? 83  GLU B OE2 1 
ATOM   4075  N N   . MET B 1 84  ? 1.859   -40.266 17.505  1.00 72.05  ? 84  MET B N   1 
ATOM   4076  C CA  . MET B 1 84  ? 0.528   -40.064 16.962  1.00 63.70  ? 84  MET B CA  1 
ATOM   4077  C C   . MET B 1 84  ? 0.398   -38.687 16.326  1.00 60.89  ? 84  MET B C   1 
ATOM   4078  O O   . MET B 1 84  ? 1.142   -37.767 16.665  1.00 65.43  ? 84  MET B O   1 
ATOM   4079  C CB  . MET B 1 84  ? -0.515  -40.207 18.069  1.00 66.14  ? 84  MET B CB  1 
ATOM   4080  C CG  . MET B 1 84  ? -0.689  -41.645 18.479  1.00 70.60  ? 84  MET B CG  1 
ATOM   4081  S SD  . MET B 1 84  ? -1.433  -42.617 17.139  1.00 70.89  ? 84  MET B SD  1 
ATOM   4082  C CE  . MET B 1 84  ? -1.429  -44.242 17.906  1.00 72.54  ? 84  MET B CE  1 
ATOM   4083  N N   . PRO B 1 85  ? -0.560  -38.531 15.385  1.00 61.22  ? 85  PRO B N   1 
ATOM   4084  C CA  . PRO B 1 85  ? -0.821  -37.258 14.709  1.00 66.76  ? 85  PRO B CA  1 
ATOM   4085  C C   . PRO B 1 85  ? -1.419  -36.142 15.564  1.00 68.84  ? 85  PRO B C   1 
ATOM   4086  O O   . PRO B 1 85  ? -2.083  -36.412 16.564  1.00 81.39  ? 85  PRO B O   1 
ATOM   4087  C CB  . PRO B 1 85  ? -1.880  -37.586 13.635  1.00 61.45  ? 85  PRO B CB  1 
ATOM   4088  C CG  . PRO B 1 85  ? -1.943  -39.098 13.552  1.00 57.66  ? 85  PRO B CG  1 
ATOM   4089  C CD  . PRO B 1 85  ? -1.401  -39.617 14.864  1.00 60.74  ? 85  PRO B CD  1 
ATOM   4090  N N   . TYR B 1 86  ? -1.216  -34.893 15.114  1.00 65.14  ? 86  TYR B N   1 
ATOM   4091  C CA  . TYR B 1 86  ? -1.962  -33.751 15.620  1.00 71.31  ? 86  TYR B CA  1 
ATOM   4092  C C   . TYR B 1 86  ? -3.450  -33.974 15.362  1.00 72.38  ? 86  TYR B C   1 
ATOM   4093  O O   . TYR B 1 86  ? -3.838  -34.168 14.205  1.00 68.17  ? 86  TYR B O   1 
ATOM   4094  C CB  . TYR B 1 86  ? -1.600  -32.444 14.902  1.00 74.20  ? 86  TYR B CB  1 
ATOM   4095  C CG  . TYR B 1 86  ? -0.239  -31.867 15.193  1.00 80.96  ? 86  TYR B CG  1 
ATOM   4096  C CD1 . TYR B 1 86  ? 0.911   -32.404 14.637  1.00 89.62  ? 86  TYR B CD1 1 
ATOM   4097  C CD2 . TYR B 1 86  ? -0.101  -30.735 15.973  1.00 84.16  ? 86  TYR B CD2 1 
ATOM   4098  C CE1 . TYR B 1 86  ? 2.161   -31.860 14.887  1.00 88.14  ? 86  TYR B CE1 1 
ATOM   4099  C CE2 . TYR B 1 86  ? 1.143   -30.176 16.231  1.00 93.03  ? 86  TYR B CE2 1 
ATOM   4100  C CZ  . TYR B 1 86  ? 2.280   -30.745 15.693  1.00 92.06  ? 86  TYR B CZ  1 
ATOM   4101  O OH  . TYR B 1 86  ? 3.508   -30.192 15.944  1.00 92.79  ? 86  TYR B OH  1 
ATOM   4102  N N   . VAL B 1 87  ? -4.268  -33.873 16.428  1.00 58.98  ? 87  VAL B N   1 
ATOM   4103  C CA  . VAL B 1 87  ? -5.718  -33.960 16.299  1.00 52.34  ? 87  VAL B CA  1 
ATOM   4104  C C   . VAL B 1 87  ? -6.221  -32.846 15.378  1.00 46.58  ? 87  VAL B C   1 
ATOM   4105  O O   . VAL B 1 87  ? -7.222  -33.016 14.678  1.00 49.21  ? 87  VAL B O   1 
ATOM   4106  C CB  . VAL B 1 87  ? -6.414  -33.911 17.681  1.00 50.05  ? 87  VAL B CB  1 
ATOM   4107  C CG1 . VAL B 1 87  ? -7.934  -33.837 17.562  1.00 49.35  ? 87  VAL B CG1 1 
ATOM   4108  C CG2 . VAL B 1 87  ? -6.005  -35.087 18.567  1.00 45.93  ? 87  VAL B CG2 1 
ATOM   4109  N N   . GLU B 1 88  ? -5.510  -31.712 15.413  1.00 45.13  ? 88  GLU B N   1 
ATOM   4110  C CA  . GLU B 1 88  ? -5.779  -30.531 14.613  1.00 50.22  ? 88  GLU B CA  1 
ATOM   4111  C C   . GLU B 1 88  ? -5.690  -30.855 13.113  1.00 52.97  ? 88  GLU B C   1 
ATOM   4112  O O   . GLU B 1 88  ? -6.402  -30.256 12.299  1.00 43.77  ? 88  GLU B O   1 
ATOM   4113  C CB  . GLU B 1 88  ? -4.773  -29.432 14.997  1.00 55.24  ? 88  GLU B CB  1 
ATOM   4114  C CG  . GLU B 1 88  ? -4.853  -28.985 16.449  1.00 59.48  ? 88  GLU B CG  1 
ATOM   4115  C CD  . GLU B 1 88  ? -3.881  -29.612 17.448  1.00 65.37  ? 88  GLU B CD  1 
ATOM   4116  O OE1 . GLU B 1 88  ? -3.721  -30.903 17.496  1.00 53.55  ? 88  GLU B OE1 1 
ATOM   4117  O OE2 . GLU B 1 88  ? -3.316  -28.799 18.253  1.00 71.52  ? 88  GLU B OE2 1 
ATOM   4118  N N   . GLY B 1 89  ? -4.782  -31.777 12.742  1.00 52.30  ? 89  GLY B N   1 
ATOM   4119  C CA  . GLY B 1 89  ? -4.615  -32.168 11.356  1.00 53.20  ? 89  GLY B CA  1 
ATOM   4120  C C   . GLY B 1 89  ? -5.821  -32.978 10.887  1.00 54.57  ? 89  GLY B C   1 
ATOM   4121  O O   . GLY B 1 89  ? -6.303  -32.816 9.760   1.00 48.61  ? 89  GLY B O   1 
ATOM   4122  N N   . HIS B 1 90  ? -6.309  -33.850 11.778  1.00 51.77  ? 90  HIS B N   1 
ATOM   4123  C CA  . HIS B 1 90  ? -7.470  -34.648 11.457  1.00 51.55  ? 90  HIS B CA  1 
ATOM   4124  C C   . HIS B 1 90  ? -8.673  -33.733 11.255  1.00 50.96  ? 90  HIS B C   1 
ATOM   4125  O O   . HIS B 1 90  ? -9.525  -34.010 10.429  1.00 46.77  ? 90  HIS B O   1 
ATOM   4126  C CB  . HIS B 1 90  ? -7.733  -35.703 12.530  1.00 53.67  ? 90  HIS B CB  1 
ATOM   4127  C CG  . HIS B 1 90  ? -8.839  -36.623 12.128  1.00 58.24  ? 90  HIS B CG  1 
ATOM   4128  N ND1 . HIS B 1 90  ? -8.853  -37.314 10.941  1.00 57.26  ? 90  HIS B ND1 1 
ATOM   4129  C CD2 . HIS B 1 90  ? -10.012 -36.899 12.752  1.00 60.63  ? 90  HIS B CD2 1 
ATOM   4130  C CE1 . HIS B 1 90  ? -9.961  -38.039 10.854  1.00 56.10  ? 90  HIS B CE1 1 
ATOM   4131  N NE2 . HIS B 1 90  ? -10.692 -37.795 11.970  1.00 63.04  ? 90  HIS B NE2 1 
ATOM   4132  N N   . PHE B 1 91  ? -8.731  -32.632 12.002  1.00 54.05  ? 91  PHE B N   1 
ATOM   4133  C CA  . PHE B 1 91  ? -9.819  -31.672 11.869  1.00 56.04  ? 91  PHE B CA  1 
ATOM   4134  C C   . PHE B 1 91  ? -9.762  -30.977 10.508  1.00 58.19  ? 91  PHE B C   1 
ATOM   4135  O O   . PHE B 1 91  ? -10.786 -30.753 9.865   1.00 54.31  ? 91  PHE B O   1 
ATOM   4136  C CB  . PHE B 1 91  ? -9.773  -30.675 13.031  1.00 55.55  ? 91  PHE B CB  1 
ATOM   4137  C CG  . PHE B 1 91  ? -11.010 -29.830 13.180  1.00 61.91  ? 91  PHE B CG  1 
ATOM   4138  C CD1 . PHE B 1 91  ? -12.277 -30.409 13.192  1.00 66.03  ? 91  PHE B CD1 1 
ATOM   4139  C CD2 . PHE B 1 91  ? -10.914 -28.455 13.328  1.00 66.28  ? 91  PHE B CD2 1 
ATOM   4140  C CE1 . PHE B 1 91  ? -13.418 -29.634 13.348  1.00 64.74  ? 91  PHE B CE1 1 
ATOM   4141  C CE2 . PHE B 1 91  ? -12.057 -27.680 13.476  1.00 65.18  ? 91  PHE B CE2 1 
ATOM   4142  C CZ  . PHE B 1 91  ? -13.304 -28.269 13.493  1.00 66.24  ? 91  PHE B CZ  1 
ATOM   4143  N N   . TYR B 1 92  ? -8.545  -30.609 10.094  1.00 65.57  ? 92  TYR B N   1 
ATOM   4144  C CA  . TYR B 1 92  ? -8.288  -30.043 8.779   1.00 58.54  ? 92  TYR B CA  1 
ATOM   4145  C C   . TYR B 1 92  ? -8.815  -30.999 7.704   1.00 51.45  ? 92  TYR B C   1 
ATOM   4146  O O   . TYR B 1 92  ? -9.546  -30.612 6.792   1.00 40.50  ? 92  TYR B O   1 
ATOM   4147  C CB  . TYR B 1 92  ? -6.787  -29.754 8.632   1.00 59.89  ? 92  TYR B CB  1 
ATOM   4148  C CG  . TYR B 1 92  ? -6.420  -29.010 7.372   1.00 68.12  ? 92  TYR B CG  1 
ATOM   4149  C CD1 . TYR B 1 92  ? -6.382  -29.655 6.142   1.00 76.50  ? 92  TYR B CD1 1 
ATOM   4150  C CD2 . TYR B 1 92  ? -6.158  -27.648 7.393   1.00 76.15  ? 92  TYR B CD2 1 
ATOM   4151  C CE1 . TYR B 1 92  ? -6.068  -28.976 4.975   1.00 79.31  ? 92  TYR B CE1 1 
ATOM   4152  C CE2 . TYR B 1 92  ? -5.856  -26.950 6.233   1.00 77.62  ? 92  TYR B CE2 1 
ATOM   4153  C CZ  . TYR B 1 92  ? -5.810  -27.616 5.021   1.00 78.17  ? 92  TYR B CZ  1 
ATOM   4154  O OH  . TYR B 1 92  ? -5.515  -26.928 3.868   1.00 91.71  ? 92  TYR B OH  1 
ATOM   4155  N N   . LEU B 1 93  ? -8.462  -32.276 7.847   1.00 45.13  ? 93  LEU B N   1 
ATOM   4156  C CA  . LEU B 1 93  ? -8.829  -33.286 6.868   1.00 48.02  ? 93  LEU B CA  1 
ATOM   4157  C C   . LEU B 1 93  ? -10.342 -33.429 6.730   1.00 51.95  ? 93  LEU B C   1 
ATOM   4158  O O   . LEU B 1 93  ? -10.851 -33.565 5.623   1.00 51.19  ? 93  LEU B O   1 
ATOM   4159  C CB  . LEU B 1 93  ? -8.209  -34.606 7.320   1.00 48.33  ? 93  LEU B CB  1 
ATOM   4160  C CG  . LEU B 1 93  ? -8.660  -35.827 6.531   1.00 49.18  ? 93  LEU B CG  1 
ATOM   4161  C CD1 . LEU B 1 93  ? -8.419  -35.609 5.039   1.00 49.94  ? 93  LEU B CD1 1 
ATOM   4162  C CD2 . LEU B 1 93  ? -7.913  -37.064 7.036   1.00 44.83  ? 93  LEU B CD2 1 
ATOM   4163  N N   . LEU B 1 94  ? -11.043 -33.440 7.877   1.00 57.75  ? 94  LEU B N   1 
ATOM   4164  C CA  . LEU B 1 94  ? -12.488 -33.593 7.906   1.00 47.76  ? 94  LEU B CA  1 
ATOM   4165  C C   . LEU B 1 94  ? -13.165 -32.380 7.285   1.00 44.76  ? 94  LEU B C   1 
ATOM   4166  O O   . LEU B 1 94  ? -14.152 -32.536 6.584   1.00 41.27  ? 94  LEU B O   1 
ATOM   4167  C CB  . LEU B 1 94  ? -12.948 -33.808 9.346   1.00 49.67  ? 94  LEU B CB  1 
ATOM   4168  C CG  . LEU B 1 94  ? -12.501 -35.124 9.983   1.00 53.32  ? 94  LEU B CG  1 
ATOM   4169  C CD1 . LEU B 1 94  ? -13.138 -35.289 11.358  1.00 56.11  ? 94  LEU B CD1 1 
ATOM   4170  C CD2 . LEU B 1 94  ? -12.831 -36.319 9.093   1.00 51.02  ? 94  LEU B CD2 1 
ATOM   4171  N N   . LEU B 1 95  ? -12.633 -31.180 7.536   1.00 50.71  ? 95  LEU B N   1 
ATOM   4172  C CA  . LEU B 1 95  ? -13.231 -29.966 6.993   1.00 50.85  ? 95  LEU B CA  1 
ATOM   4173  C C   . LEU B 1 95  ? -13.029 -29.883 5.486   1.00 55.34  ? 95  LEU B C   1 
ATOM   4174  O O   . LEU B 1 95  ? -13.969 -29.545 4.770   1.00 56.00  ? 95  LEU B O   1 
ATOM   4175  C CB  . LEU B 1 95  ? -12.623 -28.734 7.658   1.00 52.66  ? 95  LEU B CB  1 
ATOM   4176  C CG  . LEU B 1 95  ? -13.258 -28.322 8.985   1.00 60.28  ? 95  LEU B CG  1 
ATOM   4177  C CD1 . LEU B 1 95  ? -12.461 -27.194 9.640   1.00 65.49  ? 95  LEU B CD1 1 
ATOM   4178  C CD2 . LEU B 1 95  ? -14.714 -27.911 8.798   1.00 59.54  ? 95  LEU B CD2 1 
ATOM   4179  N N   . THR B 1 96  ? -11.800 -30.164 5.022   1.00 54.90  ? 96  THR B N   1 
ATOM   4180  C CA  . THR B 1 96  ? -11.394 -29.770 3.680   1.00 56.13  ? 96  THR B CA  1 
ATOM   4181  C C   . THR B 1 96  ? -11.476 -30.948 2.726   1.00 58.78  ? 96  THR B C   1 
ATOM   4182  O O   . THR B 1 96  ? -11.745 -30.733 1.552   1.00 61.75  ? 96  THR B O   1 
ATOM   4183  C CB  . THR B 1 96  ? -9.952  -29.247 3.603   1.00 54.37  ? 96  THR B CB  1 
ATOM   4184  O OG1 . THR B 1 96  ? -9.026  -30.301 3.904   1.00 49.03  ? 96  THR B OG1 1 
ATOM   4185  C CG2 . THR B 1 96  ? -9.735  -28.059 4.514   1.00 57.76  ? 96  THR B CG2 1 
ATOM   4186  N N   . GLY B 1 97  ? -11.194 -32.153 3.233   1.00 58.35  ? 97  GLY B N   1 
ATOM   4187  C CA  . GLY B 1 97  ? -11.007 -33.313 2.380   1.00 58.52  ? 97  GLY B CA  1 
ATOM   4188  C C   . GLY B 1 97  ? -9.536  -33.612 2.081   1.00 59.39  ? 97  GLY B C   1 
ATOM   4189  O O   . GLY B 1 97  ? -9.228  -34.647 1.498   1.00 60.08  ? 97  GLY B O   1 
ATOM   4190  N N   . ASP B 1 98  ? -8.628  -32.720 2.503   1.00 63.62  ? 98  ASP B N   1 
ATOM   4191  C CA  . ASP B 1 98  ? -7.223  -32.771 2.112   1.00 65.80  ? 98  ASP B CA  1 
ATOM   4192  C C   . ASP B 1 98  ? -6.356  -33.177 3.296   1.00 62.95  ? 98  ASP B C   1 
ATOM   4193  O O   . ASP B 1 98  ? -6.597  -32.683 4.400   1.00 64.30  ? 98  ASP B O   1 
ATOM   4194  C CB  . ASP B 1 98  ? -6.710  -31.390 1.686   1.00 67.76  ? 98  ASP B CB  1 
ATOM   4195  C CG  . ASP B 1 98  ? -7.367  -30.786 0.452   1.00 71.95  ? 98  ASP B CG  1 
ATOM   4196  O OD1 . ASP B 1 98  ? -8.004  -31.548 -0.326  1.00 75.20  ? 98  ASP B OD1 1 
ATOM   4197  O OD2 . ASP B 1 98  ? -7.240  -29.546 0.276   1.00 72.15  ? 98  ASP B OD2 1 
ATOM   4198  N N   . VAL B 1 99  ? -5.317  -34.000 3.060   1.00 58.69  ? 99  VAL B N   1 
ATOM   4199  C CA  . VAL B 1 99  ? -4.283  -34.183 4.075   1.00 64.95  ? 99  VAL B CA  1 
ATOM   4200  C C   . VAL B 1 99  ? -3.473  -32.895 4.162   1.00 64.31  ? 99  VAL B C   1 
ATOM   4201  O O   . VAL B 1 99  ? -2.933  -32.456 3.157   1.00 73.75  ? 99  VAL B O   1 
ATOM   4202  C CB  . VAL B 1 99  ? -3.353  -35.383 3.817   1.00 58.24  ? 99  VAL B CB  1 
ATOM   4203  C CG1 . VAL B 1 99  ? -2.255  -35.498 4.883   1.00 59.55  ? 99  VAL B CG1 1 
ATOM   4204  C CG2 . VAL B 1 99  ? -4.137  -36.680 3.729   1.00 57.84  ? 99  VAL B CG2 1 
ATOM   4205  N N   . PRO B 1 100 ? -3.392  -32.224 5.332   1.00 65.81  ? 100 PRO B N   1 
ATOM   4206  C CA  . PRO B 1 100 ? -2.584  -31.007 5.441   1.00 67.71  ? 100 PRO B CA  1 
ATOM   4207  C C   . PRO B 1 100 ? -1.070  -31.238 5.527   1.00 68.61  ? 100 PRO B C   1 
ATOM   4208  O O   . PRO B 1 100 ? -0.590  -32.276 6.010   1.00 62.30  ? 100 PRO B O   1 
ATOM   4209  C CB  . PRO B 1 100 ? -3.102  -30.369 6.737   1.00 63.62  ? 100 PRO B CB  1 
ATOM   4210  C CG  . PRO B 1 100 ? -3.508  -31.569 7.578   1.00 64.83  ? 100 PRO B CG  1 
ATOM   4211  C CD  . PRO B 1 100 ? -4.078  -32.569 6.590   1.00 61.00  ? 100 PRO B CD  1 
ATOM   4212  N N   . THR B 1 101 ? -0.333  -30.234 5.026   1.00 69.76  ? 101 THR B N   1 
ATOM   4213  C CA  . THR B 1 101 ? 1.113   -30.170 5.138   1.00 75.73  ? 101 THR B CA  1 
ATOM   4214  C C   . THR B 1 101 ? 1.450   -29.873 6.599   1.00 75.66  ? 101 THR B C   1 
ATOM   4215  O O   . THR B 1 101 ? 0.607   -29.386 7.349   1.00 70.48  ? 101 THR B O   1 
ATOM   4216  C CB  . THR B 1 101 ? 1.706   -29.124 4.172   1.00 70.93  ? 101 THR B CB  1 
ATOM   4217  O OG1 . THR B 1 101 ? 1.429   -27.795 4.625   1.00 61.10  ? 101 THR B OG1 1 
ATOM   4218  C CG2 . THR B 1 101 ? 1.192   -29.265 2.755   1.00 70.06  ? 101 THR B CG2 1 
ATOM   4219  N N   . GLU B 1 102 ? 2.694   -30.140 6.989   1.00 77.53  ? 102 GLU B N   1 
ATOM   4220  C CA  . GLU B 1 102 ? 3.137   -29.811 8.332   1.00 75.82  ? 102 GLU B CA  1 
ATOM   4221  C C   . GLU B 1 102 ? 2.962   -28.309 8.593   1.00 75.79  ? 102 GLU B C   1 
ATOM   4222  O O   . GLU B 1 102 ? 2.836   -27.900 9.737   1.00 72.29  ? 102 GLU B O   1 
ATOM   4223  C CB  . GLU B 1 102 ? 4.566   -30.304 8.541   1.00 78.62  ? 102 GLU B CB  1 
ATOM   4224  C CG  . GLU B 1 102 ? 4.923   -30.488 10.004  1.00 83.30  ? 102 GLU B CG  1 
ATOM   4225  C CD  . GLU B 1 102 ? 6.352   -30.951 10.206  1.00 97.24  ? 102 GLU B CD  1 
ATOM   4226  O OE1 . GLU B 1 102 ? 6.644   -32.084 9.789   1.00 107.61 ? 102 GLU B OE1 1 
ATOM   4227  O OE2 . GLU B 1 102 ? 7.177   -30.170 10.748  1.00 99.18  ? 102 GLU B OE2 1 
ATOM   4228  N N   . LYS B 1 103 ? 2.873   -27.480 7.549   1.00 79.54  ? 103 LYS B N   1 
ATOM   4229  C CA  . LYS B 1 103 ? 2.756   -26.039 7.728   1.00 82.08  ? 103 LYS B CA  1 
ATOM   4230  C C   . LYS B 1 103 ? 1.304   -25.639 8.017   1.00 69.97  ? 103 LYS B C   1 
ATOM   4231  O O   . LYS B 1 103 ? 1.070   -24.775 8.863   1.00 77.87  ? 103 LYS B O   1 
ATOM   4232  C CB  . LYS B 1 103 ? 3.368   -25.338 6.508   1.00 98.47  ? 103 LYS B CB  1 
ATOM   4233  C CG  . LYS B 1 103 ? 4.026   -23.990 6.783   1.00 116.03 ? 103 LYS B CG  1 
ATOM   4234  C CD  . LYS B 1 103 ? 3.113   -22.813 6.555   1.00 129.17 ? 103 LYS B CD  1 
ATOM   4235  C CE  . LYS B 1 103 ? 2.942   -22.515 5.082   1.00 136.80 ? 103 LYS B CE  1 
ATOM   4236  N NZ  . LYS B 1 103 ? 1.630   -21.882 4.809   1.00 141.31 ? 103 LYS B NZ  1 
ATOM   4237  N N   . GLU B 1 104 ? 0.339   -26.285 7.346   1.00 69.64  ? 104 GLU B N   1 
ATOM   4238  C CA  . GLU B 1 104 ? -1.087  -26.013 7.532   1.00 77.46  ? 104 GLU B CA  1 
ATOM   4239  C C   . GLU B 1 104 ? -1.623  -26.507 8.885   1.00 71.33  ? 104 GLU B C   1 
ATOM   4240  O O   . GLU B 1 104 ? -2.574  -25.942 9.416   1.00 55.17  ? 104 GLU B O   1 
ATOM   4241  C CB  . GLU B 1 104 ? -1.906  -26.695 6.439   1.00 84.99  ? 104 GLU B CB  1 
ATOM   4242  C CG  . GLU B 1 104 ? -1.551  -26.237 5.034   1.00 88.99  ? 104 GLU B CG  1 
ATOM   4243  C CD  . GLU B 1 104 ? -2.094  -27.108 3.907   1.00 81.63  ? 104 GLU B CD  1 
ATOM   4244  O OE1 . GLU B 1 104 ? -1.901  -28.344 3.941   1.00 69.36  ? 104 GLU B OE1 1 
ATOM   4245  O OE2 . GLU B 1 104 ? -2.706  -26.544 2.985   1.00 91.83  ? 104 GLU B OE2 1 
ATOM   4246  N N   . VAL B 1 105 ? -1.047  -27.588 9.422   1.00 71.64  ? 105 VAL B N   1 
ATOM   4247  C CA  . VAL B 1 105 ? -1.388  -28.092 10.745  1.00 69.89  ? 105 VAL B CA  1 
ATOM   4248  C C   . VAL B 1 105 ? -0.972  -27.088 11.811  1.00 72.66  ? 105 VAL B C   1 
ATOM   4249  O O   . VAL B 1 105 ? -1.657  -26.954 12.822  1.00 85.35  ? 105 VAL B O   1 
ATOM   4250  C CB  . VAL B 1 105 ? -0.750  -29.466 11.025  1.00 72.02  ? 105 VAL B CB  1 
ATOM   4251  C CG1 . VAL B 1 105 ? -0.876  -29.895 12.489  1.00 74.07  ? 105 VAL B CG1 1 
ATOM   4252  C CG2 . VAL B 1 105 ? -1.348  -30.526 10.117  1.00 82.22  ? 105 VAL B CG2 1 
ATOM   4253  N N   . LYS B 1 106 ? 0.148   -26.396 11.585  1.00 75.05  ? 106 LYS B N   1 
ATOM   4254  C CA  . LYS B 1 106 ? 0.687   -25.488 12.584  1.00 81.36  ? 106 LYS B CA  1 
ATOM   4255  C C   . LYS B 1 106 ? -0.138  -24.210 12.627  1.00 75.37  ? 106 LYS B C   1 
ATOM   4256  O O   . LYS B 1 106 ? -0.196  -23.561 13.667  1.00 87.39  ? 106 LYS B O   1 
ATOM   4257  C CB  . LYS B 1 106 ? 2.182   -25.249 12.368  1.00 82.45  ? 106 LYS B CB  1 
ATOM   4258  C CG  . LYS B 1 106 ? 3.008   -26.517 12.577  1.00 98.81  ? 106 LYS B CG  1 
ATOM   4259  C CD  . LYS B 1 106 ? 4.417   -26.286 13.066  1.00 104.47 ? 106 LYS B CD  1 
ATOM   4260  C CE  . LYS B 1 106 ? 4.487   -26.033 14.561  1.00 107.35 ? 106 LYS B CE  1 
ATOM   4261  N NZ  . LYS B 1 106 ? 5.760   -25.368 14.930  1.00 112.27 ? 106 LYS B NZ  1 
ATOM   4262  N N   . GLU B 1 107 ? -0.823  -23.883 11.537  1.00 67.47  ? 107 GLU B N   1 
ATOM   4263  C CA  . GLU B 1 107 ? -1.654  -22.693 11.549  1.00 74.40  ? 107 GLU B CA  1 
ATOM   4264  C C   . GLU B 1 107 ? -2.908  -22.966 12.375  1.00 64.29  ? 107 GLU B C   1 
ATOM   4265  O O   . GLU B 1 107 ? -3.346  -22.108 13.138  1.00 58.00  ? 107 GLU B O   1 
ATOM   4266  C CB  . GLU B 1 107 ? -1.941  -22.249 10.116  1.00 85.71  ? 107 GLU B CB  1 
ATOM   4267  C CG  . GLU B 1 107 ? -0.662  -21.864 9.384   1.00 109.94 ? 107 GLU B CG  1 
ATOM   4268  C CD  . GLU B 1 107 ? -0.824  -21.338 7.968   1.00 125.61 ? 107 GLU B CD  1 
ATOM   4269  O OE1 . GLU B 1 107 ? -1.314  -22.104 7.102   1.00 133.63 ? 107 GLU B OE1 1 
ATOM   4270  O OE2 . GLU B 1 107 ? -0.455  -20.159 7.734   1.00 129.64 ? 107 GLU B OE2 1 
ATOM   4271  N N   . VAL B 1 108 ? -3.452  -24.179 12.230  1.00 61.88  ? 108 VAL B N   1 
ATOM   4272  C CA  . VAL B 1 108 ? -4.644  -24.579 12.957  1.00 63.32  ? 108 VAL B CA  1 
ATOM   4273  C C   . VAL B 1 108 ? -4.338  -24.644 14.449  1.00 62.82  ? 108 VAL B C   1 
ATOM   4274  O O   . VAL B 1 108 ? -5.104  -24.116 15.258  1.00 58.51  ? 108 VAL B O   1 
ATOM   4275  C CB  . VAL B 1 108 ? -5.192  -25.934 12.469  1.00 68.28  ? 108 VAL B CB  1 
ATOM   4276  C CG1 . VAL B 1 108 ? -6.327  -26.439 13.363  1.00 72.51  ? 108 VAL B CG1 1 
ATOM   4277  C CG2 . VAL B 1 108 ? -5.637  -25.857 11.019  1.00 67.07  ? 108 VAL B CG2 1 
ATOM   4278  N N   . ALA B 1 109 ? -3.230  -25.317 14.786  1.00 62.85  ? 109 ALA B N   1 
ATOM   4279  C CA  . ALA B 1 109 ? -2.791  -25.476 16.165  1.00 68.13  ? 109 ALA B CA  1 
ATOM   4280  C C   . ALA B 1 109 ? -2.624  -24.118 16.840  1.00 62.65  ? 109 ALA B C   1 
ATOM   4281  O O   . ALA B 1 109 ? -2.996  -23.992 18.007  1.00 69.30  ? 109 ALA B O   1 
ATOM   4282  C CB  . ALA B 1 109 ? -1.511  -26.272 16.228  1.00 72.65  ? 109 ALA B CB  1 
ATOM   4283  N N   . GLU B 1 110 ? -2.072  -23.133 16.108  1.00 62.49  ? 110 GLU B N   1 
ATOM   4284  C CA  . GLU B 1 110 ? -1.934  -21.768 16.608  1.00 67.73  ? 110 GLU B CA  1 
ATOM   4285  C C   . GLU B 1 110 ? -3.312  -21.138 16.774  1.00 59.81  ? 110 GLU B C   1 
ATOM   4286  O O   . GLU B 1 110 ? -3.512  -20.356 17.699  1.00 60.05  ? 110 GLU B O   1 
ATOM   4287  C CB  . GLU B 1 110 ? -1.088  -20.857 15.706  1.00 71.45  ? 110 GLU B CB  1 
ATOM   4288  C CG  . GLU B 1 110 ? 0.416   -21.164 15.731  1.00 84.20  ? 110 GLU B CG  1 
ATOM   4289  C CD  . GLU B 1 110 ? 1.118   -21.164 17.088  1.00 92.67  ? 110 GLU B CD  1 
ATOM   4290  O OE1 . GLU B 1 110 ? 1.358   -20.057 17.613  1.00 77.49  ? 110 GLU B OE1 1 
ATOM   4291  O OE2 . GLU B 1 110 ? 1.445   -22.274 17.625  1.00 99.15  ? 110 GLU B OE2 1 
ATOM   4292  N N   . GLU B 1 111 ? -4.252  -21.460 15.882  1.00 56.40  ? 111 GLU B N   1 
ATOM   4293  C CA  . GLU B 1 111 ? -5.575  -20.869 15.984  1.00 53.38  ? 111 GLU B CA  1 
ATOM   4294  C C   . GLU B 1 111 ? -6.310  -21.472 17.182  1.00 51.49  ? 111 GLU B C   1 
ATOM   4295  O O   . GLU B 1 111 ? -7.088  -20.784 17.823  1.00 56.32  ? 111 GLU B O   1 
ATOM   4296  C CB  . GLU B 1 111 ? -6.369  -21.031 14.686  1.00 58.48  ? 111 GLU B CB  1 
ATOM   4297  C CG  . GLU B 1 111 ? -7.576  -20.114 14.590  1.00 68.10  ? 111 GLU B CG  1 
ATOM   4298  C CD  . GLU B 1 111 ? -7.292  -18.623 14.732  1.00 89.80  ? 111 GLU B CD  1 
ATOM   4299  O OE1 . GLU B 1 111 ? -6.407  -18.143 14.004  1.00 104.04 ? 111 GLU B OE1 1 
ATOM   4300  O OE2 . GLU B 1 111 ? -7.976  -17.924 15.544  1.00 102.00 ? 111 GLU B OE2 1 
ATOM   4301  N N   . PHE B 1 112 ? -6.054  -22.742 17.508  1.00 50.15  ? 112 PHE B N   1 
ATOM   4302  C CA  . PHE B 1 112 ? -6.698  -23.371 18.652  1.00 52.44  ? 112 PHE B CA  1 
ATOM   4303  C C   . PHE B 1 112 ? -6.184  -22.786 19.963  1.00 55.18  ? 112 PHE B C   1 
ATOM   4304  O O   . PHE B 1 112 ? -6.959  -22.578 20.908  1.00 54.98  ? 112 PHE B O   1 
ATOM   4305  C CB  . PHE B 1 112 ? -6.497  -24.886 18.630  1.00 51.76  ? 112 PHE B CB  1 
ATOM   4306  C CG  . PHE B 1 112 ? -7.535  -25.637 17.835  1.00 55.93  ? 112 PHE B CG  1 
ATOM   4307  C CD1 . PHE B 1 112 ? -8.386  -24.980 16.954  1.00 56.52  ? 112 PHE B CD1 1 
ATOM   4308  C CD2 . PHE B 1 112 ? -7.718  -26.997 18.031  1.00 57.92  ? 112 PHE B CD2 1 
ATOM   4309  C CE1 . PHE B 1 112 ? -9.343  -25.676 16.229  1.00 56.13  ? 112 PHE B CE1 1 
ATOM   4310  C CE2 . PHE B 1 112 ? -8.686  -27.687 17.316  1.00 64.32  ? 112 PHE B CE2 1 
ATOM   4311  C CZ  . PHE B 1 112 ? -9.498  -27.028 16.410  1.00 57.95  ? 112 PHE B CZ  1 
ATOM   4312  N N   . LYS B 1 113 ? -4.877  -22.516 20.008  1.00 55.57  ? 113 LYS B N   1 
ATOM   4313  C CA  . LYS B 1 113 ? -4.247  -21.952 21.191  1.00 53.18  ? 113 LYS B CA  1 
ATOM   4314  C C   . LYS B 1 113 ? -4.861  -20.604 21.545  1.00 50.07  ? 113 LYS B C   1 
ATOM   4315  O O   . LYS B 1 113 ? -5.121  -20.355 22.725  1.00 51.40  ? 113 LYS B O   1 
ATOM   4316  C CB  . LYS B 1 113 ? -2.738  -21.906 20.971  1.00 57.76  ? 113 LYS B CB  1 
ATOM   4317  C CG  . LYS B 1 113 ? -2.112  -23.279 21.179  1.00 66.73  ? 113 LYS B CG  1 
ATOM   4318  C CD  . LYS B 1 113 ? -0.754  -23.465 20.539  1.00 73.20  ? 113 LYS B CD  1 
ATOM   4319  C CE  . LYS B 1 113 ? -0.270  -24.886 20.708  1.00 71.60  ? 113 LYS B CE  1 
ATOM   4320  N NZ  . LYS B 1 113 ? 1.059   -25.064 20.090  1.00 81.08  ? 113 LYS B NZ  1 
ATOM   4321  N N   . LYS B 1 114 ? -5.183  -19.793 20.529  1.00 49.34  ? 114 LYS B N   1 
ATOM   4322  C CA  . LYS B 1 114 ? -5.817  -18.496 20.745  1.00 51.64  ? 114 LYS B CA  1 
ATOM   4323  C C   . LYS B 1 114 ? -7.230  -18.654 21.335  1.00 50.01  ? 114 LYS B C   1 
ATOM   4324  O O   . LYS B 1 114 ? -7.738  -17.748 21.983  1.00 40.46  ? 114 LYS B O   1 
ATOM   4325  C CB  . LYS B 1 114 ? -5.775  -17.681 19.443  1.00 57.32  ? 114 LYS B CB  1 
ATOM   4326  C CG  . LYS B 1 114 ? -4.369  -17.148 19.128  1.00 72.92  ? 114 LYS B CG  1 
ATOM   4327  C CD  . LYS B 1 114 ? -4.108  -16.447 17.781  1.00 78.52  ? 114 LYS B CD  1 
ATOM   4328  C CE  . LYS B 1 114 ? -4.956  -15.214 17.527  1.00 87.73  ? 114 LYS B CE  1 
ATOM   4329  N NZ  . LYS B 1 114 ? -4.261  -14.233 16.659  1.00 82.85  ? 114 LYS B NZ  1 
ATOM   4330  N N   . ARG B 1 115 ? -7.868  -19.821 21.166  1.00 51.26  ? 115 ARG B N   1 
ATOM   4331  C CA  . ARG B 1 115 ? -9.288  -19.940 21.441  1.00 45.32  ? 115 ARG B CA  1 
ATOM   4332  C C   . ARG B 1 115 ? -9.634  -20.939 22.543  1.00 42.41  ? 115 ARG B C   1 
ATOM   4333  O O   . ARG B 1 115 ? -10.800 -21.229 22.727  1.00 48.03  ? 115 ARG B O   1 
ATOM   4334  C CB  . ARG B 1 115 ? -9.996  -20.411 20.173  1.00 42.76  ? 115 ARG B CB  1 
ATOM   4335  C CG  . ARG B 1 115 ? -10.013 -19.392 19.047  1.00 42.46  ? 115 ARG B CG  1 
ATOM   4336  C CD  . ARG B 1 115 ? -10.646 -20.060 17.834  1.00 46.91  ? 115 ARG B CD  1 
ATOM   4337  N NE  . ARG B 1 115 ? -10.468 -19.299 16.617  1.00 46.22  ? 115 ARG B NE  1 
ATOM   4338  C CZ  . ARG B 1 115 ? -11.430 -18.929 15.788  1.00 43.47  ? 115 ARG B CZ  1 
ATOM   4339  N NH1 . ARG B 1 115 ? -12.675 -18.833 16.200  1.00 33.67  ? 115 ARG B NH1 1 
ATOM   4340  N NH2 . ARG B 1 115 ? -11.115 -18.618 14.541  1.00 44.86  ? 115 ARG B NH2 1 
ATOM   4341  N N   . ARG B 1 116 ? -8.674  -21.475 23.284  1.00 42.85  ? 116 ARG B N   1 
ATOM   4342  C CA  . ARG B 1 116 ? -8.979  -22.647 24.091  1.00 47.21  ? 116 ARG B CA  1 
ATOM   4343  C C   . ARG B 1 116 ? -9.333  -22.287 25.546  1.00 45.97  ? 116 ARG B C   1 
ATOM   4344  O O   . ARG B 1 116 ? -9.637  -23.150 26.385  1.00 43.88  ? 116 ARG B O   1 
ATOM   4345  C CB  . ARG B 1 116 ? -7.842  -23.668 23.956  1.00 50.19  ? 116 ARG B CB  1 
ATOM   4346  C CG  . ARG B 1 116 ? -6.464  -23.204 24.384  1.00 49.84  ? 116 ARG B CG  1 
ATOM   4347  C CD  . ARG B 1 116 ? -5.613  -24.439 24.667  1.00 54.57  ? 116 ARG B CD  1 
ATOM   4348  N NE  . ARG B 1 116 ? -4.837  -25.033 23.567  1.00 55.40  ? 116 ARG B NE  1 
ATOM   4349  C CZ  . ARG B 1 116 ? -3.596  -25.506 23.695  1.00 53.00  ? 116 ARG B CZ  1 
ATOM   4350  N NH1 . ARG B 1 116 ? -2.762  -25.009 24.587  1.00 50.55  ? 116 ARG B NH1 1 
ATOM   4351  N NH2 . ARG B 1 116 ? -3.173  -26.488 22.930  1.00 56.00  ? 116 ARG B NH2 1 
ATOM   4352  N N   . ALA B 1 117 ? -9.356  -20.991 25.841  1.00 45.88  ? 117 ALA B N   1 
ATOM   4353  C CA  . ALA B 1 117 ? -9.628  -20.532 27.186  1.00 40.76  ? 117 ALA B CA  1 
ATOM   4354  C C   . ALA B 1 117 ? -11.118 -20.647 27.461  1.00 36.05  ? 117 ALA B C   1 
ATOM   4355  O O   . ALA B 1 117 ? -11.939 -20.157 26.707  1.00 33.68  ? 117 ALA B O   1 
ATOM   4356  C CB  . ALA B 1 117 ? -9.113  -19.126 27.357  1.00 39.30  ? 117 ALA B CB  1 
ATOM   4357  N N   . LEU B 1 118 ? -11.415 -21.303 28.576  1.00 37.00  ? 118 LEU B N   1 
ATOM   4358  C CA  . LEU B 1 118 ? -12.754 -21.496 29.106  1.00 36.45  ? 118 LEU B CA  1 
ATOM   4359  C C   . LEU B 1 118 ? -13.278 -20.218 29.768  1.00 33.07  ? 118 LEU B C   1 
ATOM   4360  O O   . LEU B 1 118 ? -12.603 -19.619 30.606  1.00 32.17  ? 118 LEU B O   1 
ATOM   4361  C CB  . LEU B 1 118 ? -12.622 -22.626 30.131  1.00 38.16  ? 118 LEU B CB  1 
ATOM   4362  C CG  . LEU B 1 118 ? -13.738 -23.656 30.164  1.00 40.51  ? 118 LEU B CG  1 
ATOM   4363  C CD1 . LEU B 1 118 ? -13.925 -24.274 28.783  1.00 46.58  ? 118 LEU B CD1 1 
ATOM   4364  C CD2 . LEU B 1 118 ? -13.380 -24.719 31.191  1.00 39.93  ? 118 LEU B CD2 1 
ATOM   4365  N N   . PRO B 1 119 ? -14.491 -19.734 29.428  1.00 32.05  ? 119 PRO B N   1 
ATOM   4366  C CA  . PRO B 1 119 ? -15.110 -18.621 30.153  1.00 35.43  ? 119 PRO B CA  1 
ATOM   4367  C C   . PRO B 1 119 ? -15.206 -18.907 31.637  1.00 33.46  ? 119 PRO B C   1 
ATOM   4368  O O   . PRO B 1 119 ? -15.543 -20.018 32.008  1.00 40.23  ? 119 PRO B O   1 
ATOM   4369  C CB  . PRO B 1 119 ? -16.531 -18.575 29.559  1.00 34.35  ? 119 PRO B CB  1 
ATOM   4370  C CG  . PRO B 1 119 ? -16.320 -19.031 28.151  1.00 34.16  ? 119 PRO B CG  1 
ATOM   4371  C CD  . PRO B 1 119 ? -15.322 -20.165 28.302  1.00 33.85  ? 119 PRO B CD  1 
ATOM   4372  N N   . GLU B 1 120 ? -14.938 -17.907 32.463  1.00 37.43  ? 120 GLU B N   1 
ATOM   4373  C CA  . GLU B 1 120 ? -15.091 -18.054 33.907  1.00 39.82  ? 120 GLU B CA  1 
ATOM   4374  C C   . GLU B 1 120 ? -16.519 -18.471 34.255  1.00 37.41  ? 120 GLU B C   1 
ATOM   4375  O O   . GLU B 1 120 ? -16.693 -19.311 35.127  1.00 37.05  ? 120 GLU B O   1 
ATOM   4376  C CB  . GLU B 1 120 ? -14.752 -16.774 34.673  1.00 44.72  ? 120 GLU B CB  1 
ATOM   4377  C CG  . GLU B 1 120 ? -13.257 -16.550 34.767  1.00 57.96  ? 120 GLU B CG  1 
ATOM   4378  C CD  . GLU B 1 120 ? -12.531 -17.702 35.435  1.00 63.11  ? 120 GLU B CD  1 
ATOM   4379  O OE1 . GLU B 1 120 ? -12.863 -17.962 36.622  1.00 62.09  ? 120 GLU B OE1 1 
ATOM   4380  O OE2 . GLU B 1 120 ? -11.687 -18.368 34.751  1.00 69.80  ? 120 GLU B OE2 1 
ATOM   4381  N N   . TYR B 1 121 ? -17.539 -17.928 33.574  1.00 32.42  ? 121 TYR B N   1 
ATOM   4382  C CA  . TYR B 1 121 ? -18.912 -18.211 33.942  1.00 33.42  ? 121 TYR B CA  1 
ATOM   4383  C C   . TYR B 1 121 ? -19.265 -19.682 33.734  1.00 31.78  ? 121 TYR B C   1 
ATOM   4384  O O   . TYR B 1 121 ? -20.199 -20.170 34.370  1.00 32.94  ? 121 TYR B O   1 
ATOM   4385  C CB  . TYR B 1 121 ? -19.895 -17.291 33.213  1.00 32.79  ? 121 TYR B CB  1 
ATOM   4386  C CG  . TYR B 1 121 ? -19.973 -17.494 31.721  1.00 32.70  ? 121 TYR B CG  1 
ATOM   4387  C CD1 . TYR B 1 121 ? -20.664 -18.565 31.167  1.00 34.68  ? 121 TYR B CD1 1 
ATOM   4388  C CD2 . TYR B 1 121 ? -19.437 -16.549 30.864  1.00 31.53  ? 121 TYR B CD2 1 
ATOM   4389  C CE1 . TYR B 1 121 ? -20.769 -18.710 29.789  1.00 37.07  ? 121 TYR B CE1 1 
ATOM   4390  C CE2 . TYR B 1 121 ? -19.541 -16.670 29.488  1.00 32.38  ? 121 TYR B CE2 1 
ATOM   4391  C CZ  . TYR B 1 121 ? -20.180 -17.770 28.950  1.00 34.86  ? 121 TYR B CZ  1 
ATOM   4392  O OH  . TYR B 1 121 ? -20.209 -17.868 27.585  1.00 34.60  ? 121 TYR B OH  1 
ATOM   4393  N N   . VAL B 1 122 ? -18.546 -20.377 32.845  1.00 32.94  ? 122 VAL B N   1 
ATOM   4394  C CA  . VAL B 1 122 ? -18.740 -21.807 32.640  1.00 32.58  ? 122 VAL B CA  1 
ATOM   4395  C C   . VAL B 1 122 ? -18.282 -22.577 33.873  1.00 29.37  ? 122 VAL B C   1 
ATOM   4396  O O   . VAL B 1 122 ? -18.937 -23.511 34.305  1.00 31.30  ? 122 VAL B O   1 
ATOM   4397  C CB  . VAL B 1 122 ? -18.017 -22.307 31.380  1.00 30.68  ? 122 VAL B CB  1 
ATOM   4398  C CG1 . VAL B 1 122 ? -17.974 -23.817 31.355  1.00 33.75  ? 122 VAL B CG1 1 
ATOM   4399  C CG2 . VAL B 1 122 ? -18.668 -21.775 30.114  1.00 30.59  ? 122 VAL B CG2 1 
ATOM   4400  N N   . LYS B 1 123 ? -17.140 -22.216 34.420  1.00 30.51  ? 123 LYS B N   1 
ATOM   4401  C CA  . LYS B 1 123 ? -16.714 -22.790 35.683  1.00 36.16  ? 123 LYS B CA  1 
ATOM   4402  C C   . LYS B 1 123 ? -17.719 -22.493 36.811  1.00 36.92  ? 123 LYS B C   1 
ATOM   4403  O O   . LYS B 1 123 ? -18.050 -23.375 37.599  1.00 36.63  ? 123 LYS B O   1 
ATOM   4404  C CB  . LYS B 1 123 ? -15.324 -22.251 36.012  1.00 42.58  ? 123 LYS B CB  1 
ATOM   4405  C CG  . LYS B 1 123 ? -14.271 -22.525 34.954  1.00 45.29  ? 123 LYS B CG  1 
ATOM   4406  C CD  . LYS B 1 123 ? -12.985 -21.818 35.286  1.00 46.11  ? 123 LYS B CD  1 
ATOM   4407  C CE  . LYS B 1 123 ? -11.959 -21.974 34.197  1.00 48.35  ? 123 LYS B CE  1 
ATOM   4408  N NZ  . LYS B 1 123 ? -10.709 -21.308 34.610  1.00 53.88  ? 123 LYS B NZ  1 
ATOM   4409  N N   . ASP B 1 124 ? -18.185 -21.245 36.917  1.00 35.69  ? 124 ASP B N   1 
ATOM   4410  C CA  . ASP B 1 124 ? -19.186 -20.866 37.897  1.00 36.51  ? 124 ASP B CA  1 
ATOM   4411  C C   . ASP B 1 124 ? -20.425 -21.745 37.762  1.00 32.62  ? 124 ASP B C   1 
ATOM   4412  O O   . ASP B 1 124 ? -21.038 -22.134 38.756  1.00 26.27  ? 124 ASP B O   1 
ATOM   4413  C CB  . ASP B 1 124 ? -19.650 -19.422 37.694  1.00 54.09  ? 124 ASP B CB  1 
ATOM   4414  C CG  . ASP B 1 124 ? -18.568 -18.354 37.777  1.00 65.77  ? 124 ASP B CG  1 
ATOM   4415  O OD1 . ASP B 1 124 ? -17.513 -18.638 38.427  1.00 89.32  ? 124 ASP B OD1 1 
ATOM   4416  O OD2 . ASP B 1 124 ? -18.784 -17.235 37.187  1.00 74.84  ? 124 ASP B OD2 1 
ATOM   4417  N N   . THR B 1 125 ? -20.819 -22.013 36.516  1.00 30.77  ? 125 THR B N   1 
ATOM   4418  C CA  . THR B 1 125 ? -22.022 -22.781 36.266  1.00 34.38  ? 125 THR B CA  1 
ATOM   4419  C C   . THR B 1 125 ? -21.846 -24.211 36.765  1.00 36.77  ? 125 THR B C   1 
ATOM   4420  O O   . THR B 1 125 ? -22.686 -24.707 37.524  1.00 37.51  ? 125 THR B O   1 
ATOM   4421  C CB  . THR B 1 125 ? -22.430 -22.711 34.788  1.00 38.98  ? 125 THR B CB  1 
ATOM   4422  O OG1 . THR B 1 125 ? -22.692 -21.354 34.434  1.00 41.06  ? 125 THR B OG1 1 
ATOM   4423  C CG2 . THR B 1 125 ? -23.698 -23.483 34.488  1.00 41.59  ? 125 THR B CG2 1 
ATOM   4424  N N   . LEU B 1 126 ? -20.758 -24.868 36.341  1.00 34.83  ? 126 LEU B N   1 
ATOM   4425  C CA  . LEU B 1 126 ? -20.443 -26.229 36.766  1.00 35.18  ? 126 LEU B CA  1 
ATOM   4426  C C   . LEU B 1 126 ? -20.337 -26.382 38.287  1.00 38.46  ? 126 LEU B C   1 
ATOM   4427  O O   . LEU B 1 126 ? -20.580 -27.467 38.818  1.00 47.04  ? 126 LEU B O   1 
ATOM   4428  C CB  . LEU B 1 126 ? -19.104 -26.632 36.142  1.00 36.08  ? 126 LEU B CB  1 
ATOM   4429  C CG  . LEU B 1 126 ? -19.051 -26.803 34.621  1.00 38.04  ? 126 LEU B CG  1 
ATOM   4430  C CD1 . LEU B 1 126 ? -17.696 -27.328 34.189  1.00 36.50  ? 126 LEU B CD1 1 
ATOM   4431  C CD2 . LEU B 1 126 ? -20.142 -27.731 34.120  1.00 40.58  ? 126 LEU B CD2 1 
ATOM   4432  N N   . LYS B 1 127 ? -19.905 -25.338 38.997  1.00 39.05  ? 127 LYS B N   1 
ATOM   4433  C CA  . LYS B 1 127 ? -19.849 -25.381 40.452  1.00 43.31  ? 127 LYS B CA  1 
ATOM   4434  C C   . LYS B 1 127 ? -21.253 -25.266 41.060  1.00 42.80  ? 127 LYS B C   1 
ATOM   4435  O O   . LYS B 1 127 ? -21.531 -25.821 42.122  1.00 37.42  ? 127 LYS B O   1 
ATOM   4436  C CB  . LYS B 1 127 ? -19.073 -24.191 41.018  1.00 47.05  ? 127 LYS B CB  1 
ATOM   4437  C CG  . LYS B 1 127 ? -17.582 -24.153 40.742  1.00 52.52  ? 127 LYS B CG  1 
ATOM   4438  C CD  . LYS B 1 127 ? -16.969 -22.934 41.369  1.00 59.14  ? 127 LYS B CD  1 
ATOM   4439  C CE  . LYS B 1 127 ? -15.623 -22.543 40.806  1.00 67.51  ? 127 LYS B CE  1 
ATOM   4440  N NZ  . LYS B 1 127 ? -14.949 -21.581 41.716  1.00 69.08  ? 127 LYS B NZ  1 
ATOM   4441  N N   . ALA B 1 128 ? -22.109 -24.459 40.433  1.00 37.59  ? 128 ALA B N   1 
ATOM   4442  C CA  . ALA B 1 128 ? -23.471 -24.282 40.907  1.00 40.76  ? 128 ALA B CA  1 
ATOM   4443  C C   . ALA B 1 128 ? -24.276 -25.581 40.767  1.00 38.88  ? 128 ALA B C   1 
ATOM   4444  O O   . ALA B 1 128 ? -25.177 -25.851 41.566  1.00 41.41  ? 128 ALA B O   1 
ATOM   4445  C CB  . ALA B 1 128 ? -24.121 -23.141 40.162  1.00 41.75  ? 128 ALA B CB  1 
ATOM   4446  N N   . MET B 1 129 ? -23.969 -26.370 39.736  1.00 37.13  ? 129 MET B N   1 
ATOM   4447  C CA  . MET B 1 129 ? -24.570 -27.685 39.588  1.00 42.45  ? 129 MET B CA  1 
ATOM   4448  C C   . MET B 1 129 ? -23.977 -28.608 40.654  1.00 41.66  ? 129 MET B C   1 
ATOM   4449  O O   . MET B 1 129 ? -22.763 -28.627 40.827  1.00 38.19  ? 129 MET B O   1 
ATOM   4450  C CB  . MET B 1 129 ? -24.247 -28.287 38.223  1.00 42.89  ? 129 MET B CB  1 
ATOM   4451  C CG  . MET B 1 129 ? -24.951 -27.651 37.055  1.00 46.92  ? 129 MET B CG  1 
ATOM   4452  S SD  . MET B 1 129 ? -24.263 -28.374 35.502  1.00 54.85  ? 129 MET B SD  1 
ATOM   4453  C CE  . MET B 1 129 ? -25.555 -29.553 35.145  1.00 62.00  ? 129 MET B CE  1 
ATOM   4454  N N   . PRO B 1 130 ? -24.794 -29.417 41.366  1.00 37.30  ? 130 PRO B N   1 
ATOM   4455  C CA  . PRO B 1 130 ? -24.295 -30.327 42.398  1.00 37.71  ? 130 PRO B CA  1 
ATOM   4456  C C   . PRO B 1 130 ? -23.152 -31.178 41.873  1.00 34.14  ? 130 PRO B C   1 
ATOM   4457  O O   . PRO B 1 130 ? -23.182 -31.624 40.724  1.00 29.18  ? 130 PRO B O   1 
ATOM   4458  C CB  . PRO B 1 130 ? -25.512 -31.187 42.742  1.00 33.18  ? 130 PRO B CB  1 
ATOM   4459  C CG  . PRO B 1 130 ? -26.621 -30.199 42.541  1.00 35.64  ? 130 PRO B CG  1 
ATOM   4460  C CD  . PRO B 1 130 ? -26.251 -29.522 41.224  1.00 38.82  ? 130 PRO B CD  1 
ATOM   4461  N N   . ARG B 1 131 ? -22.149 -31.366 42.727  1.00 34.23  ? 131 ARG B N   1 
ATOM   4462  C CA  . ARG B 1 131 ? -20.900 -31.978 42.300  1.00 38.45  ? 131 ARG B CA  1 
ATOM   4463  C C   . ARG B 1 131 ? -21.109 -33.443 41.920  1.00 38.56  ? 131 ARG B C   1 
ATOM   4464  O O   . ARG B 1 131 ? -20.287 -34.006 41.215  1.00 47.20  ? 131 ARG B O   1 
ATOM   4465  C CB  . ARG B 1 131 ? -19.848 -31.886 43.416  1.00 36.82  ? 131 ARG B CB  1 
ATOM   4466  C CG  . ARG B 1 131 ? -18.454 -32.339 42.999  1.00 34.22  ? 131 ARG B CG  1 
ATOM   4467  C CD  . ARG B 1 131 ? -17.879 -31.482 41.915  1.00 35.91  ? 131 ARG B CD  1 
ATOM   4468  N NE  . ARG B 1 131 ? -17.928 -30.088 42.345  1.00 42.39  ? 131 ARG B NE  1 
ATOM   4469  C CZ  . ARG B 1 131 ? -16.883 -29.350 42.705  1.00 35.15  ? 131 ARG B CZ  1 
ATOM   4470  N NH1 . ARG B 1 131 ? -15.682 -29.892 42.873  1.00 37.79  ? 131 ARG B NH1 1 
ATOM   4471  N NH2 . ARG B 1 131 ? -17.086 -28.064 42.899  1.00 29.95  ? 131 ARG B NH2 1 
ATOM   4472  N N   . ASP B 1 132 ? -22.190 -34.059 42.406  1.00 39.04  ? 132 ASP B N   1 
ATOM   4473  C CA  . ASP B 1 132 ? -22.491 -35.467 42.164  1.00 38.36  ? 132 ASP B CA  1 
ATOM   4474  C C   . ASP B 1 132 ? -23.309 -35.668 40.887  1.00 37.82  ? 132 ASP B C   1 
ATOM   4475  O O   . ASP B 1 132 ? -23.746 -36.770 40.630  1.00 45.95  ? 132 ASP B O   1 
ATOM   4476  C CB  . ASP B 1 132 ? -23.265 -36.073 43.351  1.00 43.86  ? 132 ASP B CB  1 
ATOM   4477  C CG  . ASP B 1 132 ? -24.548 -35.354 43.761  1.00 41.93  ? 132 ASP B CG  1 
ATOM   4478  O OD1 . ASP B 1 132 ? -24.960 -34.432 43.020  1.00 40.13  ? 132 ASP B OD1 1 
ATOM   4479  O OD2 . ASP B 1 132 ? -25.096 -35.689 44.865  1.00 40.01  ? 132 ASP B OD2 1 
ATOM   4480  N N   . THR B 1 133 ? -23.558 -34.601 40.118  1.00 36.84  ? 133 THR B N   1 
ATOM   4481  C CA  . THR B 1 133 ? -24.098 -34.679 38.770  1.00 36.59  ? 133 THR B CA  1 
ATOM   4482  C C   . THR B 1 133 ? -23.181 -35.502 37.842  1.00 38.20  ? 133 THR B C   1 
ATOM   4483  O O   . THR B 1 133 ? -21.956 -35.417 37.883  1.00 39.04  ? 133 THR B O   1 
ATOM   4484  C CB  . THR B 1 133 ? -24.310 -33.253 38.252  1.00 35.93  ? 133 THR B CB  1 
ATOM   4485  O OG1 . THR B 1 133 ? -25.177 -32.581 39.166  1.00 36.73  ? 133 THR B OG1 1 
ATOM   4486  C CG2 . THR B 1 133 ? -24.881 -33.228 36.856  1.00 39.81  ? 133 THR B CG2 1 
ATOM   4487  N N   . HIS B 1 134 ? -23.795 -36.338 37.015  1.00 36.27  ? 134 HIS B N   1 
ATOM   4488  C CA  . HIS B 1 134 ? -23.102 -37.158 36.053  1.00 38.97  ? 134 HIS B CA  1 
ATOM   4489  C C   . HIS B 1 134 ? -22.255 -36.243 35.169  1.00 33.04  ? 134 HIS B C   1 
ATOM   4490  O O   . HIS B 1 134 ? -22.697 -35.175 34.782  1.00 33.31  ? 134 HIS B O   1 
ATOM   4491  C CB  . HIS B 1 134 ? -24.119 -38.002 35.257  1.00 42.10  ? 134 HIS B CB  1 
ATOM   4492  C CG  . HIS B 1 134 ? -23.500 -39.001 34.328  1.00 56.66  ? 134 HIS B CG  1 
ATOM   4493  N ND1 . HIS B 1 134 ? -22.939 -38.688 33.102  1.00 65.39  ? 134 HIS B ND1 1 
ATOM   4494  C CD2 . HIS B 1 134 ? -23.358 -40.347 34.491  1.00 68.79  ? 134 HIS B CD2 1 
ATOM   4495  C CE1 . HIS B 1 134 ? -22.444 -39.790 32.540  1.00 69.52  ? 134 HIS B CE1 1 
ATOM   4496  N NE2 . HIS B 1 134 ? -22.716 -40.837 33.378  1.00 72.12  ? 134 HIS B NE2 1 
ATOM   4497  N N   . PRO B 1 135 ? -20.987 -36.595 34.860  1.00 31.86  ? 135 PRO B N   1 
ATOM   4498  C CA  . PRO B 1 135 ? -20.109 -35.728 34.082  1.00 31.58  ? 135 PRO B CA  1 
ATOM   4499  C C   . PRO B 1 135 ? -20.605 -35.352 32.702  1.00 26.32  ? 135 PRO B C   1 
ATOM   4500  O O   . PRO B 1 135 ? -20.278 -34.285 32.219  1.00 30.30  ? 135 PRO B O   1 
ATOM   4501  C CB  . PRO B 1 135 ? -18.794 -36.517 33.962  1.00 33.96  ? 135 PRO B CB  1 
ATOM   4502  C CG  . PRO B 1 135 ? -19.168 -37.934 34.268  1.00 33.16  ? 135 PRO B CG  1 
ATOM   4503  C CD  . PRO B 1 135 ? -20.297 -37.827 35.270  1.00 34.10  ? 135 PRO B CD  1 
ATOM   4504  N N   . MET B 1 136 ? -21.375 -36.215 32.070  1.00 27.00  ? 136 MET B N   1 
ATOM   4505  C CA  . MET B 1 136 ? -21.926 -35.895 30.760  1.00 30.37  ? 136 MET B CA  1 
ATOM   4506  C C   . MET B 1 136 ? -22.996 -34.812 30.870  1.00 29.04  ? 136 MET B C   1 
ATOM   4507  O O   . MET B 1 136 ? -23.225 -34.064 29.920  1.00 33.48  ? 136 MET B O   1 
ATOM   4508  C CB  . MET B 1 136 ? -22.504 -37.133 30.069  1.00 34.53  ? 136 MET B CB  1 
ATOM   4509  C CG  . MET B 1 136 ? -21.434 -37.922 29.299  1.00 39.24  ? 136 MET B CG  1 
ATOM   4510  S SD  . MET B 1 136 ? -20.642 -37.091 27.845  1.00 44.39  ? 136 MET B SD  1 
ATOM   4511  C CE  . MET B 1 136 ? -22.103 -36.579 26.935  1.00 45.22  ? 136 MET B CE  1 
ATOM   4512  N N   . THR B 1 137 ? -23.650 -34.720 32.027  1.00 32.07  ? 137 THR B N   1 
ATOM   4513  C CA  . THR B 1 137 ? -24.604 -33.646 32.258  1.00 33.77  ? 137 THR B CA  1 
ATOM   4514  C C   . THR B 1 137 ? -23.818 -32.341 32.360  1.00 29.71  ? 137 THR B C   1 
ATOM   4515  O O   . THR B 1 137 ? -24.153 -31.351 31.726  1.00 28.23  ? 137 THR B O   1 
ATOM   4516  C CB  . THR B 1 137 ? -25.476 -33.926 33.490  1.00 35.30  ? 137 THR B CB  1 
ATOM   4517  O OG1 . THR B 1 137 ? -26.101 -35.193 33.314  1.00 37.54  ? 137 THR B OG1 1 
ATOM   4518  C CG2 . THR B 1 137 ? -26.570 -32.906 33.694  1.00 40.16  ? 137 THR B CG2 1 
ATOM   4519  N N   . MET B 1 138 ? -22.720 -32.378 33.104  1.00 26.89  ? 138 MET B N   1 
ATOM   4520  C CA  . MET B 1 138 ? -21.886 -31.211 33.261  1.00 28.17  ? 138 MET B CA  1 
ATOM   4521  C C   . MET B 1 138 ? -21.296 -30.787 31.927  1.00 29.31  ? 138 MET B C   1 
ATOM   4522  O O   . MET B 1 138 ? -21.295 -29.614 31.584  1.00 32.96  ? 138 MET B O   1 
ATOM   4523  C CB  . MET B 1 138 ? -20.762 -31.525 34.236  1.00 31.65  ? 138 MET B CB  1 
ATOM   4524  C CG  . MET B 1 138 ? -21.226 -31.456 35.644  1.00 37.13  ? 138 MET B CG  1 
ATOM   4525  S SD  . MET B 1 138 ? -19.892 -31.748 36.797  1.00 53.14  ? 138 MET B SD  1 
ATOM   4526  C CE  . MET B 1 138 ? -20.716 -31.231 38.315  1.00 52.12  ? 138 MET B CE  1 
ATOM   4527  N N   . PHE B 1 139 ? -20.798 -31.753 31.159  1.00 30.20  ? 139 PHE B N   1 
ATOM   4528  C CA  . PHE B 1 139 ? -20.251 -31.467 29.844  1.00 31.93  ? 139 PHE B CA  1 
ATOM   4529  C C   . PHE B 1 139 ? -21.239 -30.708 28.956  1.00 33.21  ? 139 PHE B C   1 
ATOM   4530  O O   . PHE B 1 139 ? -20.902 -29.648 28.420  1.00 31.80  ? 139 PHE B O   1 
ATOM   4531  C CB  . PHE B 1 139 ? -19.879 -32.786 29.175  1.00 34.06  ? 139 PHE B CB  1 
ATOM   4532  C CG  . PHE B 1 139 ? -18.980 -32.665 27.981  1.00 32.82  ? 139 PHE B CG  1 
ATOM   4533  C CD1 . PHE B 1 139 ? -17.789 -31.966 28.063  1.00 33.80  ? 139 PHE B CD1 1 
ATOM   4534  C CD2 . PHE B 1 139 ? -19.286 -33.322 26.810  1.00 35.26  ? 139 PHE B CD2 1 
ATOM   4535  C CE1 . PHE B 1 139 ? -16.932 -31.877 26.974  1.00 33.53  ? 139 PHE B CE1 1 
ATOM   4536  C CE2 . PHE B 1 139 ? -18.426 -33.237 25.722  1.00 39.00  ? 139 PHE B CE2 1 
ATOM   4537  C CZ  . PHE B 1 139 ? -17.263 -32.494 25.798  1.00 34.67  ? 139 PHE B CZ  1 
ATOM   4538  N N   . ALA B 1 140 ? -22.447 -31.277 28.791  1.00 32.70  ? 140 ALA B N   1 
ATOM   4539  C CA  . ALA B 1 140 ? -23.488 -30.721 27.935  1.00 34.36  ? 140 ALA B CA  1 
ATOM   4540  C C   . ALA B 1 140 ? -23.916 -29.325 28.410  1.00 32.84  ? 140 ALA B C   1 
ATOM   4541  O O   . ALA B 1 140 ? -24.127 -28.438 27.603  1.00 31.77  ? 140 ALA B O   1 
ATOM   4542  C CB  . ALA B 1 140 ? -24.662 -31.689 27.883  1.00 35.99  ? 140 ALA B CB  1 
ATOM   4543  N N   . ALA B 1 141 ? -24.002 -29.111 29.723  1.00 33.62  ? 141 ALA B N   1 
ATOM   4544  C CA  . ALA B 1 141 ? -24.324 -27.805 30.278  1.00 37.29  ? 141 ALA B CA  1 
ATOM   4545  C C   . ALA B 1 141 ? -23.208 -26.774 30.087  1.00 36.27  ? 141 ALA B C   1 
ATOM   4546  O O   . ALA B 1 141 ? -23.477 -25.587 29.940  1.00 37.90  ? 141 ALA B O   1 
ATOM   4547  C CB  . ALA B 1 141 ? -24.625 -27.954 31.746  1.00 37.19  ? 141 ALA B CB  1 
ATOM   4548  N N   . GLY B 1 142 ? -21.952 -27.197 30.165  1.00 39.58  ? 142 GLY B N   1 
ATOM   4549  C CA  . GLY B 1 142 ? -20.852 -26.292 29.864  1.00 42.30  ? 142 GLY B CA  1 
ATOM   4550  C C   . GLY B 1 142 ? -20.890 -25.768 28.426  1.00 37.15  ? 142 GLY B C   1 
ATOM   4551  O O   . GLY B 1 142 ? -20.582 -24.610 28.175  1.00 41.33  ? 142 GLY B O   1 
ATOM   4552  N N   . ILE B 1 143 ? -21.274 -26.640 27.495  1.00 37.19  ? 143 ILE B N   1 
ATOM   4553  C CA  . ILE B 1 143 ? -21.365 -26.288 26.086  1.00 39.49  ? 143 ILE B CA  1 
ATOM   4554  C C   . ILE B 1 143 ? -22.515 -25.298 25.897  1.00 40.80  ? 143 ILE B C   1 
ATOM   4555  O O   . ILE B 1 143 ? -22.377 -24.238 25.288  1.00 40.35  ? 143 ILE B O   1 
ATOM   4556  C CB  . ILE B 1 143 ? -21.623 -27.559 25.256  1.00 36.55  ? 143 ILE B CB  1 
ATOM   4557  C CG1 . ILE B 1 143 ? -20.445 -28.534 25.328  1.00 35.29  ? 143 ILE B CG1 1 
ATOM   4558  C CG2 . ILE B 1 143 ? -21.994 -27.187 23.823  1.00 36.19  ? 143 ILE B CG2 1 
ATOM   4559  C CD1 . ILE B 1 143 ? -20.790 -29.962 24.896  1.00 37.03  ? 143 ILE B CD1 1 
ATOM   4560  N N   . LEU B 1 144 ? -23.665 -25.705 26.425  1.00 40.01  ? 144 LEU B N   1 
ATOM   4561  C CA  . LEU B 1 144 ? -24.903 -24.957 26.349  1.00 40.73  ? 144 LEU B CA  1 
ATOM   4562  C C   . LEU B 1 144 ? -24.721 -23.523 26.849  1.00 41.60  ? 144 LEU B C   1 
ATOM   4563  O O   . LEU B 1 144 ? -25.209 -22.579 26.213  1.00 40.83  ? 144 LEU B O   1 
ATOM   4564  C CB  . LEU B 1 144 ? -25.948 -25.695 27.204  1.00 41.77  ? 144 LEU B CB  1 
ATOM   4565  C CG  . LEU B 1 144 ? -27.365 -25.133 27.104  1.00 43.14  ? 144 LEU B CG  1 
ATOM   4566  C CD1 . LEU B 1 144 ? -27.742 -24.894 25.641  1.00 37.04  ? 144 LEU B CD1 1 
ATOM   4567  C CD2 . LEU B 1 144 ? -28.372 -26.059 27.767  1.00 47.68  ? 144 LEU B CD2 1 
ATOM   4568  N N   . ALA B 1 145 ? -24.049 -23.370 28.009  1.00 37.63  ? 145 ALA B N   1 
ATOM   4569  C CA  . ALA B 1 145 ? -23.856 -22.074 28.649  1.00 33.98  ? 145 ALA B CA  1 
ATOM   4570  C C   . ALA B 1 145 ? -23.118 -21.116 27.728  1.00 33.54  ? 145 ALA B C   1 
ATOM   4571  O O   . ALA B 1 145 ? -23.390 -19.923 27.773  1.00 44.66  ? 145 ALA B O   1 
ATOM   4572  C CB  . ALA B 1 145 ? -23.094 -22.260 29.932  1.00 33.33  ? 145 ALA B CB  1 
ATOM   4573  N N   . MET B 1 146 ? -22.215 -21.663 26.892  1.00 35.54  ? 146 MET B N   1 
ATOM   4574  C CA  . MET B 1 146 ? -21.359 -20.894 25.995  1.00 32.93  ? 146 MET B CA  1 
ATOM   4575  C C   . MET B 1 146 ? -22.078 -20.430 24.735  1.00 30.00  ? 146 MET B C   1 
ATOM   4576  O O   . MET B 1 146 ? -21.482 -19.752 23.910  1.00 30.35  ? 146 MET B O   1 
ATOM   4577  C CB  . MET B 1 146 ? -20.149 -21.745 25.601  1.00 34.64  ? 146 MET B CB  1 
ATOM   4578  C CG  . MET B 1 146 ? -19.048 -21.711 26.681  1.00 44.96  ? 146 MET B CG  1 
ATOM   4579  S SD  . MET B 1 146 ? -17.475 -22.652 26.391  1.00 42.90  ? 146 MET B SD  1 
ATOM   4580  C CE  . MET B 1 146 ? -18.084 -24.280 25.927  1.00 42.79  ? 146 MET B CE  1 
ATOM   4581  N N   . GLN B 1 147 ? -23.340 -20.816 24.575  1.00 31.85  ? 147 GLN B N   1 
ATOM   4582  C CA  . GLN B 1 147 ? -24.188 -20.364 23.476  1.00 34.30  ? 147 GLN B CA  1 
ATOM   4583  C C   . GLN B 1 147 ? -24.301 -18.826 23.464  1.00 34.60  ? 147 GLN B C   1 
ATOM   4584  O O   . GLN B 1 147 ? -24.551 -18.206 22.422  1.00 30.57  ? 147 GLN B O   1 
ATOM   4585  C CB  . GLN B 1 147 ? -25.570 -21.017 23.610  1.00 30.70  ? 147 GLN B CB  1 
ATOM   4586  C CG  . GLN B 1 147 ? -26.492 -20.771 22.426  1.00 30.35  ? 147 GLN B CG  1 
ATOM   4587  C CD  . GLN B 1 147 ? -27.202 -19.447 22.485  1.00 30.29  ? 147 GLN B CD  1 
ATOM   4588  O OE1 . GLN B 1 147 ? -27.598 -18.997 23.564  1.00 31.87  ? 147 GLN B OE1 1 
ATOM   4589  N NE2 . GLN B 1 147 ? -27.328 -18.811 21.325  1.00 27.80  ? 147 GLN B NE2 1 
ATOM   4590  N N   . ARG B 1 148 ? -24.134 -18.210 24.640  1.00 35.20  ? 148 ARG B N   1 
ATOM   4591  C CA  . ARG B 1 148 ? -24.040 -16.762 24.782  1.00 34.11  ? 148 ARG B CA  1 
ATOM   4592  C C   . ARG B 1 148 ? -23.021 -16.140 23.818  1.00 36.40  ? 148 ARG B C   1 
ATOM   4593  O O   . ARG B 1 148 ? -23.181 -14.982 23.442  1.00 44.62  ? 148 ARG B O   1 
ATOM   4594  C CB  . ARG B 1 148 ? -23.650 -16.441 26.222  1.00 34.74  ? 148 ARG B CB  1 
ATOM   4595  C CG  . ARG B 1 148 ? -23.554 -14.959 26.568  1.00 38.79  ? 148 ARG B CG  1 
ATOM   4596  C CD  . ARG B 1 148 ? -23.072 -14.861 28.016  1.00 38.14  ? 148 ARG B CD  1 
ATOM   4597  N NE  . ARG B 1 148 ? -22.714 -13.516 28.437  1.00 36.76  ? 148 ARG B NE  1 
ATOM   4598  C CZ  . ARG B 1 148 ? -21.588 -12.883 28.127  1.00 39.42  ? 148 ARG B CZ  1 
ATOM   4599  N NH1 . ARG B 1 148 ? -20.698 -13.398 27.298  1.00 45.08  ? 148 ARG B NH1 1 
ATOM   4600  N NH2 . ARG B 1 148 ? -21.330 -11.717 28.670  1.00 43.35  ? 148 ARG B NH2 1 
ATOM   4601  N N   . GLU B 1 149 ? -21.984 -16.890 23.420  1.00 37.00  ? 149 GLU B N   1 
ATOM   4602  C CA  . GLU B 1 149 ? -20.882 -16.377 22.605  1.00 37.35  ? 149 GLU B CA  1 
ATOM   4603  C C   . GLU B 1 149 ? -21.051 -16.717 21.124  1.00 38.22  ? 149 GLU B C   1 
ATOM   4604  O O   . GLU B 1 149 ? -20.107 -16.559 20.345  1.00 41.70  ? 149 GLU B O   1 
ATOM   4605  C CB  . GLU B 1 149 ? -19.543 -17.013 23.020  1.00 39.28  ? 149 GLU B CB  1 
ATOM   4606  C CG  . GLU B 1 149 ? -19.321 -17.096 24.528  1.00 45.65  ? 149 GLU B CG  1 
ATOM   4607  C CD  . GLU B 1 149 ? -19.435 -15.770 25.267  1.00 49.62  ? 149 GLU B CD  1 
ATOM   4608  O OE1 . GLU B 1 149 ? -19.367 -14.693 24.589  1.00 50.43  ? 149 GLU B OE1 1 
ATOM   4609  O OE2 . GLU B 1 149 ? -19.619 -15.811 26.521  1.00 54.27  ? 149 GLU B OE2 1 
ATOM   4610  N N   . SER B 1 150 ? -22.221 -17.243 20.744  1.00 35.09  ? 150 SER B N   1 
ATOM   4611  C CA  . SER B 1 150 ? -22.408 -17.757 19.409  1.00 37.28  ? 150 SER B CA  1 
ATOM   4612  C C   . SER B 1 150 ? -22.345 -16.601 18.410  1.00 39.24  ? 150 SER B C   1 
ATOM   4613  O O   . SER B 1 150 ? -23.073 -15.611 18.539  1.00 36.41  ? 150 SER B O   1 
ATOM   4614  C CB  . SER B 1 150 ? -23.701 -18.534 19.288  1.00 38.11  ? 150 SER B CB  1 
ATOM   4615  O OG  . SER B 1 150 ? -23.931 -18.884 17.924  1.00 42.36  ? 150 SER B OG  1 
ATOM   4616  N N   . LYS B 1 151 ? -21.474 -16.774 17.405  1.00 41.85  ? 151 LYS B N   1 
ATOM   4617  C CA  . LYS B 1 151 ? -21.289 -15.804 16.339  1.00 41.85  ? 151 LYS B CA  1 
ATOM   4618  C C   . LYS B 1 151 ? -22.411 -15.956 15.330  1.00 41.06  ? 151 LYS B C   1 
ATOM   4619  O O   . LYS B 1 151 ? -22.971 -14.976 14.838  1.00 38.38  ? 151 LYS B O   1 
ATOM   4620  C CB  . LYS B 1 151 ? -19.917 -16.014 15.693  1.00 44.17  ? 151 LYS B CB  1 
ATOM   4621  C CG  . LYS B 1 151 ? -18.812 -15.277 16.415  1.00 49.41  ? 151 LYS B CG  1 
ATOM   4622  C CD  . LYS B 1 151 ? -17.603 -16.083 16.706  1.00 58.13  ? 151 LYS B CD  1 
ATOM   4623  C CE  . LYS B 1 151 ? -16.595 -15.217 17.435  1.00 67.07  ? 151 LYS B CE  1 
ATOM   4624  N NZ  . LYS B 1 151 ? -15.368 -15.957 17.792  1.00 75.24  ? 151 LYS B NZ  1 
ATOM   4625  N N   . PHE B 1 152 ? -22.727 -17.217 15.051  1.00 44.67  ? 152 PHE B N   1 
ATOM   4626  C CA  . PHE B 1 152 ? -23.862 -17.544 14.216  1.00 49.21  ? 152 PHE B CA  1 
ATOM   4627  C C   . PHE B 1 152 ? -25.138 -16.909 14.770  1.00 45.15  ? 152 PHE B C   1 
ATOM   4628  O O   . PHE B 1 152 ? -25.900 -16.315 14.020  1.00 47.25  ? 152 PHE B O   1 
ATOM   4629  C CB  . PHE B 1 152 ? -24.010 -19.064 14.126  1.00 58.35  ? 152 PHE B CB  1 
ATOM   4630  C CG  . PHE B 1 152 ? -24.992 -19.494 13.069  1.00 62.62  ? 152 PHE B CG  1 
ATOM   4631  C CD1 . PHE B 1 152 ? -24.576 -19.659 11.759  1.00 61.05  ? 152 PHE B CD1 1 
ATOM   4632  C CD2 . PHE B 1 152 ? -26.336 -19.645 13.376  1.00 62.33  ? 152 PHE B CD2 1 
ATOM   4633  C CE1 . PHE B 1 152 ? -25.481 -20.039 10.787  1.00 60.18  ? 152 PHE B CE1 1 
ATOM   4634  C CE2 . PHE B 1 152 ? -27.239 -20.003 12.398  1.00 63.26  ? 152 PHE B CE2 1 
ATOM   4635  C CZ  . PHE B 1 152 ? -26.805 -20.211 11.110  1.00 63.23  ? 152 PHE B CZ  1 
ATOM   4636  N N   . ALA B 1 153 ? -25.399 -17.063 16.078  1.00 44.42  ? 153 ALA B N   1 
ATOM   4637  C CA  . ALA B 1 153 ? -26.628 -16.541 16.658  1.00 40.78  ? 153 ALA B CA  1 
ATOM   4638  C C   . ALA B 1 153 ? -26.648 -15.027 16.494  1.00 43.88  ? 153 ALA B C   1 
ATOM   4639  O O   . ALA B 1 153 ? -27.633 -14.490 15.986  1.00 42.20  ? 153 ALA B O   1 
ATOM   4640  C CB  . ALA B 1 153 ? -26.756 -16.960 18.099  1.00 40.76  ? 153 ALA B CB  1 
ATOM   4641  N N   . ALA B 1 154 ? -25.525 -14.368 16.849  1.00 42.94  ? 154 ALA B N   1 
ATOM   4642  C CA  . ALA B 1 154 ? -25.357 -12.925 16.689  1.00 44.05  ? 154 ALA B CA  1 
ATOM   4643  C C   . ALA B 1 154 ? -25.645 -12.487 15.254  1.00 40.16  ? 154 ALA B C   1 
ATOM   4644  O O   . ALA B 1 154 ? -26.349 -11.501 15.043  1.00 38.97  ? 154 ALA B O   1 
ATOM   4645  C CB  . ALA B 1 154 ? -23.956 -12.508 17.095  1.00 41.91  ? 154 ALA B CB  1 
ATOM   4646  N N   . TYR B 1 155 ? -25.050 -13.209 14.292  1.00 44.07  ? 155 TYR B N   1 
ATOM   4647  C CA  . TYR B 1 155 ? -25.204 -12.961 12.859  1.00 49.36  ? 155 TYR B CA  1 
ATOM   4648  C C   . TYR B 1 155 ? -26.686 -12.981 12.476  1.00 48.94  ? 155 TYR B C   1 
ATOM   4649  O O   . TYR B 1 155 ? -27.197 -12.006 11.935  1.00 48.13  ? 155 TYR B O   1 
ATOM   4650  C CB  . TYR B 1 155 ? -24.331 -13.973 12.115  1.00 47.97  ? 155 TYR B CB  1 
ATOM   4651  C CG  . TYR B 1 155 ? -24.543 -14.205 10.638  1.00 57.30  ? 155 TYR B CG  1 
ATOM   4652  C CD1 . TYR B 1 155 ? -24.027 -13.351 9.673   1.00 59.48  ? 155 TYR B CD1 1 
ATOM   4653  C CD2 . TYR B 1 155 ? -25.156 -15.369 10.195  1.00 56.44  ? 155 TYR B CD2 1 
ATOM   4654  C CE1 . TYR B 1 155 ? -24.152 -13.623 8.313   1.00 62.65  ? 155 TYR B CE1 1 
ATOM   4655  C CE2 . TYR B 1 155 ? -25.294 -15.654 8.845   1.00 60.42  ? 155 TYR B CE2 1 
ATOM   4656  C CZ  . TYR B 1 155 ? -24.785 -14.784 7.895   1.00 66.73  ? 155 TYR B CZ  1 
ATOM   4657  O OH  . TYR B 1 155 ? -24.924 -15.119 6.563   1.00 64.71  ? 155 TYR B OH  1 
ATOM   4658  N N   . TYR B 1 156 ? -27.378 -14.066 12.828  1.00 48.78  ? 156 TYR B N   1 
ATOM   4659  C CA  . TYR B 1 156 ? -28.783 -14.195 12.502  1.00 52.43  ? 156 TYR B CA  1 
ATOM   4660  C C   . TYR B 1 156 ? -29.605 -13.105 13.195  1.00 49.27  ? 156 TYR B C   1 
ATOM   4661  O O   . TYR B 1 156 ? -30.428 -12.447 12.561  1.00 50.13  ? 156 TYR B O   1 
ATOM   4662  C CB  . TYR B 1 156 ? -29.300 -15.587 12.859  1.00 54.63  ? 156 TYR B CB  1 
ATOM   4663  C CG  . TYR B 1 156 ? -30.698 -15.795 12.336  1.00 58.13  ? 156 TYR B CG  1 
ATOM   4664  C CD1 . TYR B 1 156 ? -31.781 -15.148 12.919  1.00 57.45  ? 156 TYR B CD1 1 
ATOM   4665  C CD2 . TYR B 1 156 ? -30.932 -16.579 11.218  1.00 56.91  ? 156 TYR B CD2 1 
ATOM   4666  C CE1 . TYR B 1 156 ? -33.063 -15.313 12.428  1.00 61.25  ? 156 TYR B CE1 1 
ATOM   4667  C CE2 . TYR B 1 156 ? -32.203 -16.732 10.691  1.00 56.92  ? 156 TYR B CE2 1 
ATOM   4668  C CZ  . TYR B 1 156 ? -33.271 -16.097 11.302  1.00 63.77  ? 156 TYR B CZ  1 
ATOM   4669  O OH  . TYR B 1 156 ? -34.539 -16.233 10.794  1.00 80.14  ? 156 TYR B OH  1 
ATOM   4670  N N   . ASN B 1 157 ? -29.392 -12.917 14.498  1.00 47.84  ? 157 ASN B N   1 
ATOM   4671  C CA  . ASN B 1 157 ? -30.230 -12.022 15.301  1.00 56.80  ? 157 ASN B CA  1 
ATOM   4672  C C   . ASN B 1 157 ? -30.021 -10.562 14.900  1.00 56.53  ? 157 ASN B C   1 
ATOM   4673  O O   . ASN B 1 157 ? -30.897 -9.745  15.115  1.00 61.82  ? 157 ASN B O   1 
ATOM   4674  C CB  . ASN B 1 157 ? -29.967 -12.130 16.810  1.00 55.94  ? 157 ASN B CB  1 
ATOM   4675  C CG  . ASN B 1 157 ? -30.358 -13.470 17.409  1.00 57.43  ? 157 ASN B CG  1 
ATOM   4676  O OD1 . ASN B 1 157 ? -31.208 -14.194 16.884  1.00 55.91  ? 157 ASN B OD1 1 
ATOM   4677  N ND2 . ASN B 1 157 ? -29.727 -13.825 18.516  1.00 60.08  ? 157 ASN B ND2 1 
ATOM   4678  N N   . ALA B 1 158 ? -28.844 -10.239 14.357  1.00 58.97  ? 158 ALA B N   1 
ATOM   4679  C CA  . ALA B 1 158 ? -28.552 -8.926  13.799  1.00 60.19  ? 158 ALA B CA  1 
ATOM   4680  C C   . ALA B 1 158 ? -29.100 -8.735  12.374  1.00 65.86  ? 158 ALA B C   1 
ATOM   4681  O O   . ALA B 1 158 ? -28.769 -7.736  11.731  1.00 66.38  ? 158 ALA B O   1 
ATOM   4682  C CB  . ALA B 1 158 ? -27.059 -8.730  13.807  1.00 54.80  ? 158 ALA B CB  1 
ATOM   4683  N N   . GLY B 1 159 ? -29.897 -9.682  11.852  1.00 61.16  ? 159 GLY B N   1 
ATOM   4684  C CA  . GLY B 1 159 ? -30.547 -9.512  10.559  1.00 58.02  ? 159 GLY B CA  1 
ATOM   4685  C C   . GLY B 1 159 ? -29.622 -9.624  9.335   1.00 61.72  ? 159 GLY B C   1 
ATOM   4686  O O   . GLY B 1 159 ? -30.003 -9.181  8.253   1.00 54.99  ? 159 GLY B O   1 
ATOM   4687  N N   . LYS B 1 160 ? -28.441 -10.251 9.475   1.00 66.22  ? 160 LYS B N   1 
ATOM   4688  C CA  . LYS B 1 160 ? -27.459 -10.330 8.394   1.00 65.28  ? 160 LYS B CA  1 
ATOM   4689  C C   . LYS B 1 160 ? -27.441 -11.710 7.730   1.00 66.55  ? 160 LYS B C   1 
ATOM   4690  O O   . LYS B 1 160 ? -26.523 -12.007 6.956   1.00 61.35  ? 160 LYS B O   1 
ATOM   4691  C CB  . LYS B 1 160 ? -26.033 -10.110 8.914   1.00 66.74  ? 160 LYS B CB  1 
ATOM   4692  C CG  . LYS B 1 160 ? -25.860 -9.042  9.979   1.00 74.79  ? 160 LYS B CG  1 
ATOM   4693  C CD  . LYS B 1 160 ? -24.407 -8.891  10.397  1.00 80.20  ? 160 LYS B CD  1 
ATOM   4694  C CE  . LYS B 1 160 ? -24.235 -8.198  11.734  1.00 84.15  ? 160 LYS B CE  1 
ATOM   4695  N NZ  . LYS B 1 160 ? -22.844 -7.726  11.927  1.00 89.35  ? 160 LYS B NZ  1 
ATOM   4696  N N   . PHE B 1 161 ? -28.422 -12.568 8.065   1.00 70.42  ? 161 PHE B N   1 
ATOM   4697  C CA  . PHE B 1 161 ? -28.458 -13.924 7.529   1.00 65.42  ? 161 PHE B CA  1 
ATOM   4698  C C   . PHE B 1 161 ? -28.528 -13.877 6.004   1.00 59.30  ? 161 PHE B C   1 
ATOM   4699  O O   . PHE B 1 161 ? -29.306 -13.124 5.437   1.00 64.48  ? 161 PHE B O   1 
ATOM   4700  C CB  . PHE B 1 161 ? -29.653 -14.754 8.019   1.00 60.42  ? 161 PHE B CB  1 
ATOM   4701  C CG  . PHE B 1 161 ? -29.599 -16.170 7.498   1.00 57.22  ? 161 PHE B CG  1 
ATOM   4702  C CD1 . PHE B 1 161 ? -28.693 -17.079 8.024   1.00 51.82  ? 161 PHE B CD1 1 
ATOM   4703  C CD2 . PHE B 1 161 ? -30.378 -16.564 6.421   1.00 57.34  ? 161 PHE B CD2 1 
ATOM   4704  C CE1 . PHE B 1 161 ? -28.608 -18.370 7.533   1.00 53.27  ? 161 PHE B CE1 1 
ATOM   4705  C CE2 . PHE B 1 161 ? -30.292 -17.858 5.927   1.00 58.85  ? 161 PHE B CE2 1 
ATOM   4706  C CZ  . PHE B 1 161 ? -29.406 -18.758 6.483   1.00 55.33  ? 161 PHE B CZ  1 
ATOM   4707  N N   . ASN B 1 162 ? -27.749 -14.741 5.361   1.00 50.92  ? 162 ASN B N   1 
ATOM   4708  C CA  . ASN B 1 162 ? -27.596 -14.751 3.926   1.00 51.30  ? 162 ASN B CA  1 
ATOM   4709  C C   . ASN B 1 162 ? -27.316 -16.193 3.557   1.00 54.29  ? 162 ASN B C   1 
ATOM   4710  O O   . ASN B 1 162 ? -26.359 -16.756 4.070   1.00 67.04  ? 162 ASN B O   1 
ATOM   4711  C CB  . ASN B 1 162 ? -26.469 -13.793 3.534   1.00 56.13  ? 162 ASN B CB  1 
ATOM   4712  C CG  . ASN B 1 162 ? -26.133 -13.813 2.063   1.00 58.29  ? 162 ASN B CG  1 
ATOM   4713  O OD1 . ASN B 1 162 ? -25.582 -14.781 1.560   1.00 66.89  ? 162 ASN B OD1 1 
ATOM   4714  N ND2 . ASN B 1 162 ? -26.459 -12.745 1.361   1.00 67.29  ? 162 ASN B ND2 1 
ATOM   4715  N N   . LYS B 1 163 ? -28.131 -16.789 2.693   1.00 61.00  ? 163 LYS B N   1 
ATOM   4716  C CA  . LYS B 1 163 ? -27.992 -18.210 2.416   1.00 66.64  ? 163 LYS B CA  1 
ATOM   4717  C C   . LYS B 1 163 ? -26.533 -18.563 2.106   1.00 59.90  ? 163 LYS B C   1 
ATOM   4718  O O   . LYS B 1 163 ? -26.110 -19.666 2.424   1.00 63.15  ? 163 LYS B O   1 
ATOM   4719  C CB  . LYS B 1 163 ? -28.934 -18.684 1.300   1.00 84.34  ? 163 LYS B CB  1 
ATOM   4720  C CG  . LYS B 1 163 ? -29.505 -20.081 1.548   1.00 101.16 ? 163 LYS B CG  1 
ATOM   4721  C CD  . LYS B 1 163 ? -29.879 -20.856 0.295   1.00 107.36 ? 163 LYS B CD  1 
ATOM   4722  C CE  . LYS B 1 163 ? -28.732 -21.666 -0.281  1.00 111.85 ? 163 LYS B CE  1 
ATOM   4723  N NZ  . LYS B 1 163 ? -29.084 -22.355 -1.550  1.00 112.94 ? 163 LYS B NZ  1 
ATOM   4724  N N   . ASN B 1 164 ? -25.730 -17.648 1.539   1.00 61.58  ? 164 ASN B N   1 
ATOM   4725  C CA  . ASN B 1 164 ? -24.438 -18.023 0.959   1.00 63.56  ? 164 ASN B CA  1 
ATOM   4726  C C   . ASN B 1 164 ? -23.290 -18.021 1.969   1.00 61.11  ? 164 ASN B C   1 
ATOM   4727  O O   . ASN B 1 164 ? -22.401 -18.867 1.875   1.00 56.55  ? 164 ASN B O   1 
ATOM   4728  C CB  . ASN B 1 164 ? -24.055 -17.136 -0.226  1.00 66.46  ? 164 ASN B CB  1 
ATOM   4729  C CG  . ASN B 1 164 ? -25.088 -17.236 -1.325  1.00 66.13  ? 164 ASN B CG  1 
ATOM   4730  O OD1 . ASN B 1 164 ? -25.360 -18.330 -1.813  1.00 67.83  ? 164 ASN B OD1 1 
ATOM   4731  N ND2 . ASN B 1 164 ? -25.733 -16.125 -1.643  1.00 63.94  ? 164 ASN B ND2 1 
ATOM   4732  N N   . THR B 1 165 ? -23.328 -17.091 2.935   1.00 61.51  ? 165 THR B N   1 
ATOM   4733  C CA  . THR B 1 165 ? -22.211 -16.820 3.834   1.00 60.01  ? 165 THR B CA  1 
ATOM   4734  C C   . THR B 1 165 ? -22.489 -17.319 5.257   1.00 61.86  ? 165 THR B C   1 
ATOM   4735  O O   . THR B 1 165 ? -21.676 -17.098 6.151   1.00 74.53  ? 165 THR B O   1 
ATOM   4736  C CB  . THR B 1 165 ? -21.913 -15.317 3.826   1.00 58.84  ? 165 THR B CB  1 
ATOM   4737  O OG1 . THR B 1 165 ? -23.044 -14.634 4.393   1.00 57.98  ? 165 THR B OG1 1 
ATOM   4738  C CG2 . THR B 1 165 ? -21.585 -14.811 2.433   1.00 52.84  ? 165 THR B CG2 1 
ATOM   4739  N N   . ALA B 1 166 ? -23.617 -18.025 5.448   1.00 60.62  ? 166 ALA B N   1 
ATOM   4740  C CA  . ALA B 1 166 ? -24.011 -18.599 6.726   1.00 54.72  ? 166 ALA B CA  1 
ATOM   4741  C C   . ALA B 1 166 ? -22.927 -19.530 7.295   1.00 55.40  ? 166 ALA B C   1 
ATOM   4742  O O   . ALA B 1 166 ? -22.769 -19.629 8.526   1.00 51.29  ? 166 ALA B O   1 
ATOM   4743  C CB  . ALA B 1 166 ? -25.319 -19.338 6.562   1.00 52.64  ? 166 ALA B CB  1 
ATOM   4744  N N   . TRP B 1 167 ? -22.167 -20.214 6.421   1.00 43.51  ? 167 TRP B N   1 
ATOM   4745  C CA  . TRP B 1 167 ? -21.204 -21.172 6.926   1.00 43.17  ? 167 TRP B CA  1 
ATOM   4746  C C   . TRP B 1 167 ? -20.052 -20.448 7.621   1.00 41.45  ? 167 TRP B C   1 
ATOM   4747  O O   . TRP B 1 167 ? -19.319 -21.047 8.417   1.00 39.69  ? 167 TRP B O   1 
ATOM   4748  C CB  . TRP B 1 167 ? -20.680 -22.101 5.839   1.00 44.33  ? 167 TRP B CB  1 
ATOM   4749  C CG  . TRP B 1 167 ? -19.866 -21.373 4.816   1.00 48.18  ? 167 TRP B CG  1 
ATOM   4750  C CD1 . TRP B 1 167 ? -20.353 -20.767 3.711   1.00 45.29  ? 167 TRP B CD1 1 
ATOM   4751  C CD2 . TRP B 1 167 ? -18.449 -21.102 4.836   1.00 49.20  ? 167 TRP B CD2 1 
ATOM   4752  N NE1 . TRP B 1 167 ? -19.343 -20.169 3.024   1.00 49.69  ? 167 TRP B NE1 1 
ATOM   4753  C CE2 . TRP B 1 167 ? -18.162 -20.354 3.687   1.00 46.49  ? 167 TRP B CE2 1 
ATOM   4754  C CE3 . TRP B 1 167 ? -17.387 -21.440 5.685   1.00 48.71  ? 167 TRP B CE3 1 
ATOM   4755  C CZ2 . TRP B 1 167 ? -16.877 -19.923 3.369   1.00 48.68  ? 167 TRP B CZ2 1 
ATOM   4756  C CZ3 . TRP B 1 167 ? -16.114 -21.019 5.372   1.00 49.10  ? 167 TRP B CZ3 1 
ATOM   4757  C CH2 . TRP B 1 167 ? -15.863 -20.272 4.227   1.00 48.83  ? 167 TRP B CH2 1 
ATOM   4758  N N   . GLU B 1 168 ? -19.879 -19.167 7.310   1.00 40.30  ? 168 GLU B N   1 
ATOM   4759  C CA  . GLU B 1 168 ? -18.707 -18.454 7.793   1.00 45.34  ? 168 GLU B CA  1 
ATOM   4760  C C   . GLU B 1 168 ? -18.728 -18.298 9.319   1.00 46.79  ? 168 GLU B C   1 
ATOM   4761  O O   . GLU B 1 168 ? -17.822 -18.810 9.990   1.00 48.97  ? 168 GLU B O   1 
ATOM   4762  C CB  . GLU B 1 168 ? -18.566 -17.151 7.016   1.00 49.26  ? 168 GLU B CB  1 
ATOM   4763  C CG  . GLU B 1 168 ? -18.296 -17.440 5.550   1.00 65.79  ? 168 GLU B CG  1 
ATOM   4764  C CD  . GLU B 1 168 ? -17.832 -16.239 4.746   1.00 71.45  ? 168 GLU B CD  1 
ATOM   4765  O OE1 . GLU B 1 168 ? -18.485 -15.920 3.720   1.00 70.72  ? 168 GLU B OE1 1 
ATOM   4766  O OE2 . GLU B 1 168 ? -16.811 -15.626 5.154   1.00 80.86  ? 168 GLU B OE2 1 
ATOM   4767  N N   . PRO B 1 169 ? -19.731 -17.614 9.937   1.00 41.02  ? 169 PRO B N   1 
ATOM   4768  C CA  . PRO B 1 169 ? -19.876 -17.613 11.399  1.00 37.05  ? 169 PRO B CA  1 
ATOM   4769  C C   . PRO B 1 169 ? -19.981 -18.998 12.028  1.00 38.75  ? 169 PRO B C   1 
ATOM   4770  O O   . PRO B 1 169 ? -19.435 -19.230 13.104  1.00 40.88  ? 169 PRO B O   1 
ATOM   4771  C CB  . PRO B 1 169 ? -21.188 -16.879 11.658  1.00 39.17  ? 169 PRO B CB  1 
ATOM   4772  C CG  . PRO B 1 169 ? -21.902 -16.873 10.313  1.00 40.62  ? 169 PRO B CG  1 
ATOM   4773  C CD  . PRO B 1 169 ? -20.796 -16.853 9.278   1.00 39.14  ? 169 PRO B CD  1 
ATOM   4774  N N   . MET B 1 170 ? -20.656 -19.924 11.331  1.00 41.27  ? 170 MET B N   1 
ATOM   4775  C CA  . MET B 1 170 ? -20.789 -21.283 11.813  1.00 43.39  ? 170 MET B CA  1 
ATOM   4776  C C   . MET B 1 170 ? -19.399 -21.920 11.931  1.00 44.95  ? 170 MET B C   1 
ATOM   4777  O O   . MET B 1 170 ? -19.115 -22.598 12.911  1.00 43.51  ? 170 MET B O   1 
ATOM   4778  C CB  . MET B 1 170 ? -21.718 -22.093 10.895  1.00 48.82  ? 170 MET B CB  1 
ATOM   4779  C CG  . MET B 1 170 ? -21.860 -23.594 11.268  1.00 52.02  ? 170 MET B CG  1 
ATOM   4780  S SD  . MET B 1 170 ? -22.521 -23.985 12.954  1.00 59.61  ? 170 MET B SD  1 
ATOM   4781  C CE  . MET B 1 170 ? -24.252 -23.585 12.733  1.00 48.43  ? 170 MET B CE  1 
ATOM   4782  N N   . PHE B 1 171 ? -18.499 -21.640 10.983  1.00 46.01  ? 171 PHE B N   1 
ATOM   4783  C CA  . PHE B 1 171 ? -17.117 -22.113 11.044  1.00 45.12  ? 171 PHE B CA  1 
ATOM   4784  C C   . PHE B 1 171 ? -16.332 -21.511 12.216  1.00 44.11  ? 171 PHE B C   1 
ATOM   4785  O O   . PHE B 1 171 ? -15.439 -22.169 12.758  1.00 37.38  ? 171 PHE B O   1 
ATOM   4786  C CB  . PHE B 1 171 ? -16.400 -21.777 9.731   1.00 49.10  ? 171 PHE B CB  1 
ATOM   4787  C CG  . PHE B 1 171 ? -14.897 -21.902 9.764   1.00 53.25  ? 171 PHE B CG  1 
ATOM   4788  C CD1 . PHE B 1 171 ? -14.285 -23.121 9.539   1.00 56.14  ? 171 PHE B CD1 1 
ATOM   4789  C CD2 . PHE B 1 171 ? -14.086 -20.807 10.025  1.00 53.29  ? 171 PHE B CD2 1 
ATOM   4790  C CE1 . PHE B 1 171 ? -12.901 -23.245 9.574   1.00 60.11  ? 171 PHE B CE1 1 
ATOM   4791  C CE2 . PHE B 1 171 ? -12.705 -20.930 10.062  1.00 54.91  ? 171 PHE B CE2 1 
ATOM   4792  C CZ  . PHE B 1 171 ? -12.110 -22.149 9.836   1.00 58.27  ? 171 PHE B CZ  1 
ATOM   4793  N N   . GLU B 1 172 ? -16.616 -20.249 12.571  1.00 45.76  ? 172 GLU B N   1 
ATOM   4794  C CA  . GLU B 1 172 ? -15.924 -19.610 13.678  1.00 47.20  ? 172 GLU B CA  1 
ATOM   4795  C C   . GLU B 1 172 ? -16.380 -20.227 15.001  1.00 49.29  ? 172 GLU B C   1 
ATOM   4796  O O   . GLU B 1 172 ? -15.545 -20.517 15.868  1.00 49.06  ? 172 GLU B O   1 
ATOM   4797  C CB  . GLU B 1 172 ? -16.180 -18.102 13.687  1.00 54.69  ? 172 GLU B CB  1 
ATOM   4798  C CG  . GLU B 1 172 ? -15.538 -17.353 12.519  1.00 59.52  ? 172 GLU B CG  1 
ATOM   4799  C CD  . GLU B 1 172 ? -14.017 -17.456 12.421  1.00 59.01  ? 172 GLU B CD  1 
ATOM   4800  O OE1 . GLU B 1 172 ? -13.360 -17.468 13.506  1.00 54.06  ? 172 GLU B OE1 1 
ATOM   4801  O OE2 . GLU B 1 172 ? -13.477 -17.501 11.267  1.00 52.18  ? 172 GLU B OE2 1 
ATOM   4802  N N   . ASP B 1 173 ? -17.699 -20.438 15.138  1.00 44.15  ? 173 ASP B N   1 
ATOM   4803  C CA  . ASP B 1 173 ? -18.257 -21.136 16.287  1.00 44.60  ? 173 ASP B CA  1 
ATOM   4804  C C   . ASP B 1 173 ? -17.628 -22.524 16.406  1.00 46.28  ? 173 ASP B C   1 
ATOM   4805  O O   . ASP B 1 173 ? -17.317 -22.967 17.514  1.00 52.65  ? 173 ASP B O   1 
ATOM   4806  C CB  . ASP B 1 173 ? -19.783 -21.203 16.203  1.00 42.37  ? 173 ASP B CB  1 
ATOM   4807  C CG  . ASP B 1 173 ? -20.444 -19.902 16.627  1.00 45.58  ? 173 ASP B CG  1 
ATOM   4808  O OD1 . ASP B 1 173 ? -19.720 -19.058 17.177  1.00 45.27  ? 173 ASP B OD1 1 
ATOM   4809  O OD2 . ASP B 1 173 ? -21.677 -19.737 16.422  1.00 46.02  ? 173 ASP B OD2 1 
ATOM   4810  N N   . ALA B 1 174 ? -17.419 -23.191 15.263  1.00 41.69  ? 174 ALA B N   1 
ATOM   4811  C CA  . ALA B 1 174 ? -16.848 -24.525 15.250  1.00 42.33  ? 174 ALA B CA  1 
ATOM   4812  C C   . ALA B 1 174 ? -15.401 -24.485 15.731  1.00 42.26  ? 174 ALA B C   1 
ATOM   4813  O O   . ALA B 1 174 ? -15.004 -25.316 16.539  1.00 42.76  ? 174 ALA B O   1 
ATOM   4814  C CB  . ALA B 1 174 ? -16.970 -25.135 13.880  1.00 42.54  ? 174 ALA B CB  1 
ATOM   4815  N N   . MET B 1 175 ? -14.612 -23.509 15.272  1.00 43.44  ? 175 MET B N   1 
ATOM   4816  C CA  . MET B 1 175 ? -13.221 -23.417 15.705  1.00 42.84  ? 175 MET B CA  1 
ATOM   4817  C C   . MET B 1 175 ? -13.144 -23.144 17.211  1.00 39.05  ? 175 MET B C   1 
ATOM   4818  O O   . MET B 1 175 ? -12.332 -23.742 17.922  1.00 39.37  ? 175 MET B O   1 
ATOM   4819  C CB  . MET B 1 175 ? -12.529 -22.287 14.946  1.00 55.15  ? 175 MET B CB  1 
ATOM   4820  C CG  . MET B 1 175 ? -12.306 -22.611 13.460  1.00 60.95  ? 175 MET B CG  1 
ATOM   4821  S SD  . MET B 1 175 ? -11.041 -23.878 13.162  1.00 64.25  ? 175 MET B SD  1 
ATOM   4822  C CE  . MET B 1 175 ? -9.560  -23.087 13.788  1.00 63.12  ? 175 MET B CE  1 
ATOM   4823  N N   . ASP B 1 176 ? -14.033 -22.256 17.689  1.00 39.84  ? 176 ASP B N   1 
ATOM   4824  C CA  . ASP B 1 176 ? -14.097 -21.845 19.086  1.00 42.02  ? 176 ASP B CA  1 
ATOM   4825  C C   . ASP B 1 176 ? -14.512 -23.005 19.974  1.00 40.38  ? 176 ASP B C   1 
ATOM   4826  O O   . ASP B 1 176 ? -13.882 -23.253 20.995  1.00 44.56  ? 176 ASP B O   1 
ATOM   4827  C CB  . ASP B 1 176 ? -15.088 -20.700 19.346  1.00 41.93  ? 176 ASP B CB  1 
ATOM   4828  C CG  . ASP B 1 176 ? -14.623 -19.310 18.907  1.00 46.37  ? 176 ASP B CG  1 
ATOM   4829  O OD1 . ASP B 1 176 ? -13.411 -18.997 19.048  1.00 53.89  ? 176 ASP B OD1 1 
ATOM   4830  O OD2 . ASP B 1 176 ? -15.480 -18.515 18.461  1.00 46.51  ? 176 ASP B OD2 1 
ATOM   4831  N N   . LEU B 1 177 ? -15.592 -23.693 19.611  1.00 38.50  ? 177 LEU B N   1 
ATOM   4832  C CA  . LEU B 1 177 ? -16.080 -24.758 20.459  1.00 37.59  ? 177 LEU B CA  1 
ATOM   4833  C C   . LEU B 1 177 ? -15.095 -25.924 20.431  1.00 37.95  ? 177 LEU B C   1 
ATOM   4834  O O   . LEU B 1 177 ? -14.782 -26.501 21.476  1.00 39.81  ? 177 LEU B O   1 
ATOM   4835  C CB  . LEU B 1 177 ? -17.487 -25.147 20.002  1.00 44.68  ? 177 LEU B CB  1 
ATOM   4836  C CG  . LEU B 1 177 ? -18.161 -26.251 20.818  1.00 49.27  ? 177 LEU B CG  1 
ATOM   4837  C CD1 . LEU B 1 177 ? -18.047 -25.996 22.332  1.00 50.04  ? 177 LEU B CD1 1 
ATOM   4838  C CD2 . LEU B 1 177 ? -19.610 -26.384 20.389  1.00 48.22  ? 177 LEU B CD2 1 
ATOM   4839  N N   . MET B 1 178 ? -14.537 -26.235 19.261  1.00 38.29  ? 178 MET B N   1 
ATOM   4840  C CA  . MET B 1 178 ? -13.635 -27.369 19.174  1.00 41.50  ? 178 MET B CA  1 
ATOM   4841  C C   . MET B 1 178 ? -12.399 -27.119 20.051  1.00 39.22  ? 178 MET B C   1 
ATOM   4842  O O   . MET B 1 178 ? -11.919 -28.047 20.707  1.00 36.63  ? 178 MET B O   1 
ATOM   4843  C CB  . MET B 1 178 ? -13.240 -27.678 17.717  1.00 45.76  ? 178 MET B CB  1 
ATOM   4844  C CG  . MET B 1 178 ? -12.519 -29.037 17.552  1.00 49.96  ? 178 MET B CG  1 
ATOM   4845  S SD  . MET B 1 178 ? -13.514 -30.533 18.057  1.00 55.16  ? 178 MET B SD  1 
ATOM   4846  C CE  . MET B 1 178 ? -12.536 -31.199 19.401  1.00 55.34  ? 178 MET B CE  1 
ATOM   4847  N N   . ALA B 1 179 ? -11.899 -25.870 20.075  1.00 38.38  ? 179 ALA B N   1 
ATOM   4848  C CA  . ALA B 1 179 ? -10.668 -25.539 20.792  1.00 35.91  ? 179 ALA B CA  1 
ATOM   4849  C C   . ALA B 1 179 ? -10.846 -25.620 22.310  1.00 35.32  ? 179 ALA B C   1 
ATOM   4850  O O   . ALA B 1 179 ? -9.860  -25.853 23.003  1.00 38.67  ? 179 ALA B O   1 
ATOM   4851  C CB  . ALA B 1 179 ? -10.178 -24.166 20.370  1.00 37.95  ? 179 ALA B CB  1 
ATOM   4852  N N   . LYS B 1 180 ? -12.087 -25.460 22.812  1.00 37.44  ? 180 LYS B N   1 
ATOM   4853  C CA  . LYS B 1 180 ? -12.392 -25.426 24.243  1.00 35.35  ? 180 LYS B CA  1 
ATOM   4854  C C   . LYS B 1 180 ? -12.872 -26.755 24.826  1.00 36.82  ? 180 LYS B C   1 
ATOM   4855  O O   . LYS B 1 180 ? -12.760 -26.926 26.037  1.00 46.03  ? 180 LYS B O   1 
ATOM   4856  C CB  . LYS B 1 180 ? -13.542 -24.469 24.558  1.00 35.22  ? 180 LYS B CB  1 
ATOM   4857  C CG  . LYS B 1 180 ? -13.310 -23.024 24.172  1.00 40.05  ? 180 LYS B CG  1 
ATOM   4858  C CD  . LYS B 1 180 ? -14.478 -22.117 24.414  1.00 43.32  ? 180 LYS B CD  1 
ATOM   4859  C CE  . LYS B 1 180 ? -14.428 -20.881 23.550  1.00 50.16  ? 180 LYS B CE  1 
ATOM   4860  N NZ  . LYS B 1 180 ? -13.117 -20.197 23.685  1.00 55.27  ? 180 LYS B NZ  1 
ATOM   4861  N N   . LEU B 1 181 ? -13.446 -27.674 24.025  1.00 35.13  ? 181 LEU B N   1 
ATOM   4862  C CA  . LEU B 1 181 ? -14.034 -28.898 24.573  1.00 34.68  ? 181 LEU B CA  1 
ATOM   4863  C C   . LEU B 1 181 ? -13.043 -29.725 25.399  1.00 35.77  ? 181 LEU B C   1 
ATOM   4864  O O   . LEU B 1 181 ? -13.433 -30.391 26.356  1.00 45.86  ? 181 LEU B O   1 
ATOM   4865  C CB  . LEU B 1 181 ? -14.552 -29.774 23.434  1.00 36.24  ? 181 LEU B CB  1 
ATOM   4866  C CG  . LEU B 1 181 ? -15.829 -29.303 22.759  1.00 37.89  ? 181 LEU B CG  1 
ATOM   4867  C CD1 . LEU B 1 181 ? -16.200 -30.235 21.606  1.00 34.73  ? 181 LEU B CD1 1 
ATOM   4868  C CD2 . LEU B 1 181 ? -16.939 -29.214 23.780  1.00 35.57  ? 181 LEU B CD2 1 
ATOM   4869  N N   . PRO B 1 182 ? -11.755 -29.838 25.023  1.00 33.51  ? 182 PRO B N   1 
ATOM   4870  C CA  . PRO B 1 182 ? -10.813 -30.599 25.845  1.00 35.76  ? 182 PRO B CA  1 
ATOM   4871  C C   . PRO B 1 182 ? -10.553 -29.947 27.202  1.00 38.11  ? 182 PRO B C   1 
ATOM   4872  O O   . PRO B 1 182 ? -10.526 -30.638 28.208  1.00 38.31  ? 182 PRO B O   1 
ATOM   4873  C CB  . PRO B 1 182 ? -9.547  -30.668 24.970  1.00 36.45  ? 182 PRO B CB  1 
ATOM   4874  C CG  . PRO B 1 182 ? -10.053 -30.396 23.567  1.00 33.22  ? 182 PRO B CG  1 
ATOM   4875  C CD  . PRO B 1 182 ? -11.172 -29.396 23.745  1.00 32.12  ? 182 PRO B CD  1 
ATOM   4876  N N   . SER B 1 183 ? -10.390 -28.621 27.225  1.00 38.20  ? 183 SER B N   1 
ATOM   4877  C CA  . SER B 1 183 ? -10.355 -27.879 28.479  1.00 40.61  ? 183 SER B CA  1 
ATOM   4878  C C   . SER B 1 183 ? -11.612 -28.140 29.319  1.00 37.59  ? 183 SER B C   1 
ATOM   4879  O O   . SER B 1 183 ? -11.521 -28.338 30.530  1.00 40.96  ? 183 SER B O   1 
ATOM   4880  C CB  . SER B 1 183 ? -10.166 -26.397 28.256  1.00 41.36  ? 183 SER B CB  1 
ATOM   4881  O OG  . SER B 1 183 ? -8.971  -26.114 27.515  1.00 38.25  ? 183 SER B OG  1 
ATOM   4882  N N   . LEU B 1 184 ? -12.796 -28.117 28.692  1.00 34.53  ? 184 LEU B N   1 
ATOM   4883  C CA  . LEU B 1 184 ? -14.031 -28.338 29.435  1.00 31.75  ? 184 LEU B CA  1 
ATOM   4884  C C   . LEU B 1 184 ? -14.015 -29.732 30.050  1.00 29.51  ? 184 LEU B C   1 
ATOM   4885  O O   . LEU B 1 184 ? -14.273 -29.896 31.238  1.00 29.27  ? 184 LEU B O   1 
ATOM   4886  C CB  . LEU B 1 184 ? -15.244 -28.188 28.521  1.00 31.71  ? 184 LEU B CB  1 
ATOM   4887  C CG  . LEU B 1 184 ? -16.582 -28.489 29.204  1.00 32.44  ? 184 LEU B CG  1 
ATOM   4888  C CD1 . LEU B 1 184 ? -16.674 -27.787 30.545  1.00 28.82  ? 184 LEU B CD1 1 
ATOM   4889  C CD2 . LEU B 1 184 ? -17.743 -28.073 28.322  1.00 36.77  ? 184 LEU B CD2 1 
ATOM   4890  N N   . GLY B 1 185 ? -13.685 -30.727 29.233  1.00 31.40  ? 185 GLY B N   1 
ATOM   4891  C CA  . GLY B 1 185 ? -13.614 -32.107 29.691  1.00 31.64  ? 185 GLY B CA  1 
ATOM   4892  C C   . GLY B 1 185 ? -12.673 -32.268 30.878  1.00 27.50  ? 185 GLY B C   1 
ATOM   4893  O O   . GLY B 1 185 ? -13.018 -32.887 31.888  1.00 24.84  ? 185 GLY B O   1 
ATOM   4894  N N   . ALA B 1 186 ? -11.476 -31.702 30.733  1.00 32.23  ? 186 ALA B N   1 
ATOM   4895  C CA  . ALA B 1 186 ? -10.460 -31.749 31.777  1.00 33.04  ? 186 ALA B CA  1 
ATOM   4896  C C   . ALA B 1 186 ? -10.955 -31.066 33.050  1.00 32.42  ? 186 ALA B C   1 
ATOM   4897  O O   . ALA B 1 186 ? -10.742 -31.620 34.123  1.00 34.71  ? 186 ALA B O   1 
ATOM   4898  C CB  . ALA B 1 186 ? -9.187  -31.112 31.310  1.00 30.17  ? 186 ALA B CB  1 
ATOM   4899  N N   . TYR B 1 187 ? -11.632 -29.910 32.943  1.00 29.48  ? 187 TYR B N   1 
ATOM   4900  C CA  . TYR B 1 187 ? -12.113 -29.223 34.138  1.00 31.98  ? 187 TYR B CA  1 
ATOM   4901  C C   . TYR B 1 187 ? -13.015 -30.130 34.966  1.00 30.31  ? 187 TYR B C   1 
ATOM   4902  O O   . TYR B 1 187 ? -12.891 -30.208 36.197  1.00 28.74  ? 187 TYR B O   1 
ATOM   4903  C CB  . TYR B 1 187 ? -12.937 -27.970 33.841  1.00 33.57  ? 187 TYR B CB  1 
ATOM   4904  C CG  . TYR B 1 187 ? -13.080 -27.080 35.056  1.00 32.45  ? 187 TYR B CG  1 
ATOM   4905  C CD1 . TYR B 1 187 ? -12.110 -26.131 35.369  1.00 34.33  ? 187 TYR B CD1 1 
ATOM   4906  C CD2 . TYR B 1 187 ? -14.150 -27.218 35.933  1.00 35.62  ? 187 TYR B CD2 1 
ATOM   4907  C CE1 . TYR B 1 187 ? -12.214 -25.315 36.496  1.00 35.79  ? 187 TYR B CE1 1 
ATOM   4908  C CE2 . TYR B 1 187 ? -14.277 -26.412 37.069  1.00 39.92  ? 187 TYR B CE2 1 
ATOM   4909  C CZ  . TYR B 1 187 ? -13.295 -25.465 37.363  1.00 41.84  ? 187 TYR B CZ  1 
ATOM   4910  O OH  . TYR B 1 187 ? -13.364 -24.658 38.485  1.00 43.86  ? 187 TYR B OH  1 
ATOM   4911  N N   . ILE B 1 188 ? -13.925 -30.809 34.257  1.00 31.17  ? 188 ILE B N   1 
ATOM   4912  C CA  . ILE B 1 188 ? -14.873 -31.724 34.875  1.00 27.77  ? 188 ILE B CA  1 
ATOM   4913  C C   . ILE B 1 188 ? -14.135 -32.895 35.527  1.00 27.93  ? 188 ILE B C   1 
ATOM   4914  O O   . ILE B 1 188 ? -14.425 -33.230 36.692  1.00 24.64  ? 188 ILE B O   1 
ATOM   4915  C CB  . ILE B 1 188 ? -15.930 -32.165 33.852  1.00 24.92  ? 188 ILE B CB  1 
ATOM   4916  C CG1 . ILE B 1 188 ? -16.784 -30.977 33.420  1.00 23.64  ? 188 ILE B CG1 1 
ATOM   4917  C CG2 . ILE B 1 188 ? -16.799 -33.295 34.415  1.00 25.24  ? 188 ILE B CG2 1 
ATOM   4918  C CD1 . ILE B 1 188 ? -17.595 -31.285 32.200  1.00 24.49  ? 188 ILE B CD1 1 
ATOM   4919  N N   . TYR B 1 189 ? -13.159 -33.474 34.802  1.00 26.11  ? 189 TYR B N   1 
ATOM   4920  C CA  . TYR B 1 189 ? -12.389 -34.566 35.357  1.00 27.52  ? 189 TYR B CA  1 
ATOM   4921  C C   . TYR B 1 189 ? -11.797 -34.167 36.698  1.00 29.50  ? 189 TYR B C   1 
ATOM   4922  O O   . TYR B 1 189 ? -11.889 -34.927 37.649  1.00 31.87  ? 189 TYR B O   1 
ATOM   4923  C CB  . TYR B 1 189 ? -11.194 -34.946 34.484  1.00 31.99  ? 189 TYR B CB  1 
ATOM   4924  C CG  . TYR B 1 189 ? -10.501 -36.214 34.914  1.00 32.07  ? 189 TYR B CG  1 
ATOM   4925  C CD1 . TYR B 1 189 ? -11.198 -37.401 34.933  1.00 32.11  ? 189 TYR B CD1 1 
ATOM   4926  C CD2 . TYR B 1 189 ? -9.163  -36.252 35.269  1.00 36.40  ? 189 TYR B CD2 1 
ATOM   4927  C CE1 . TYR B 1 189 ? -10.604 -38.591 35.316  1.00 36.52  ? 189 TYR B CE1 1 
ATOM   4928  C CE2 . TYR B 1 189 ? -8.553  -37.435 35.668  1.00 38.12  ? 189 TYR B CE2 1 
ATOM   4929  C CZ  . TYR B 1 189 ? -9.278  -38.616 35.698  1.00 36.19  ? 189 TYR B CZ  1 
ATOM   4930  O OH  . TYR B 1 189 ? -8.748  -39.841 36.073  1.00 39.48  ? 189 TYR B OH  1 
ATOM   4931  N N   . ARG B 1 190 ? -11.149 -32.996 36.735  1.00 29.24  ? 190 ARG B N   1 
ATOM   4932  C CA  . ARG B 1 190 ? -10.390 -32.571 37.892  1.00 27.77  ? 190 ARG B CA  1 
ATOM   4933  C C   . ARG B 1 190 ? -11.316 -32.200 39.035  1.00 29.38  ? 190 ARG B C   1 
ATOM   4934  O O   . ARG B 1 190 ? -11.053 -32.552 40.190  1.00 28.90  ? 190 ARG B O   1 
ATOM   4935  C CB  . ARG B 1 190 ? -9.551  -31.345 37.539  1.00 29.54  ? 190 ARG B CB  1 
ATOM   4936  C CG  . ARG B 1 190 ? -8.546  -31.574 36.413  1.00 30.16  ? 190 ARG B CG  1 
ATOM   4937  C CD  . ARG B 1 190 ? -7.551  -32.675 36.744  1.00 30.00  ? 190 ARG B CD  1 
ATOM   4938  N NE  . ARG B 1 190 ? -6.623  -32.222 37.757  1.00 32.62  ? 190 ARG B NE  1 
ATOM   4939  C CZ  . ARG B 1 190 ? -5.661  -32.982 38.276  1.00 38.60  ? 190 ARG B CZ  1 
ATOM   4940  N NH1 . ARG B 1 190 ? -5.305  -34.114 37.681  1.00 38.35  ? 190 ARG B NH1 1 
ATOM   4941  N NH2 . ARG B 1 190 ? -5.069  -32.605 39.400  1.00 33.44  ? 190 ARG B NH2 1 
ATOM   4942  N N   . MET B 1 191 ? -12.374 -31.449 38.710  1.00 31.34  ? 191 MET B N   1 
ATOM   4943  C CA  . MET B 1 191 ? -13.289 -30.934 39.732  1.00 31.37  ? 191 MET B CA  1 
ATOM   4944  C C   . MET B 1 191 ? -14.024 -32.092 40.416  1.00 31.02  ? 191 MET B C   1 
ATOM   4945  O O   . MET B 1 191 ? -14.309 -32.034 41.615  1.00 36.75  ? 191 MET B O   1 
ATOM   4946  C CB  . MET B 1 191 ? -14.265 -29.914 39.127  1.00 30.67  ? 191 MET B CB  1 
ATOM   4947  C CG  . MET B 1 191 ? -15.609 -30.478 38.768  1.00 36.96  ? 191 MET B CG  1 
ATOM   4948  S SD  . MET B 1 191 ? -16.781 -29.243 38.112  1.00 43.56  ? 191 MET B SD  1 
ATOM   4949  C CE  . MET B 1 191 ? -16.803 -28.049 39.438  1.00 42.06  ? 191 MET B CE  1 
ATOM   4950  N N   . LYS B 1 192 ? -14.294 -33.165 39.660  1.00 30.02  ? 192 LYS B N   1 
ATOM   4951  C CA  . LYS B 1 192 ? -15.068 -34.281 40.180  1.00 30.18  ? 192 LYS B CA  1 
ATOM   4952  C C   . LYS B 1 192 ? -14.137 -35.312 40.817  1.00 32.42  ? 192 LYS B C   1 
ATOM   4953  O O   . LYS B 1 192 ? -14.441 -35.833 41.893  1.00 34.44  ? 192 LYS B O   1 
ATOM   4954  C CB  . LYS B 1 192 ? -15.918 -34.950 39.086  1.00 30.90  ? 192 LYS B CB  1 
ATOM   4955  C CG  . LYS B 1 192 ? -17.284 -34.322 38.806  1.00 31.13  ? 192 LYS B CG  1 
ATOM   4956  C CD  . LYS B 1 192 ? -18.237 -35.159 37.961  1.00 33.79  ? 192 LYS B CD  1 
ATOM   4957  C CE  . LYS B 1 192 ? -18.810 -36.380 38.675  1.00 36.75  ? 192 LYS B CE  1 
ATOM   4958  N NZ  . LYS B 1 192 ? -20.014 -36.070 39.489  1.00 38.43  ? 192 LYS B NZ  1 
ATOM   4959  N N   . TYR B 1 193 ? -13.001 -35.599 40.169  1.00 32.57  ? 193 TYR B N   1 
ATOM   4960  C CA  . TYR B 1 193 ? -12.293 -36.852 40.394  1.00 30.97  ? 193 TYR B CA  1 
ATOM   4961  C C   . TYR B 1 193 ? -10.887 -36.643 40.955  1.00 34.00  ? 193 TYR B C   1 
ATOM   4962  O O   . TYR B 1 193 ? -10.295 -37.605 41.427  1.00 45.40  ? 193 TYR B O   1 
ATOM   4963  C CB  . TYR B 1 193 ? -12.240 -37.637 39.083  1.00 29.22  ? 193 TYR B CB  1 
ATOM   4964  C CG  . TYR B 1 193 ? -13.592 -38.061 38.568  1.00 31.48  ? 193 TYR B CG  1 
ATOM   4965  C CD1 . TYR B 1 193 ? -14.472 -38.778 39.384  1.00 34.10  ? 193 TYR B CD1 1 
ATOM   4966  C CD2 . TYR B 1 193 ? -14.015 -37.757 37.276  1.00 33.15  ? 193 TYR B CD2 1 
ATOM   4967  C CE1 . TYR B 1 193 ? -15.733 -39.173 38.942  1.00 32.39  ? 193 TYR B CE1 1 
ATOM   4968  C CE2 . TYR B 1 193 ? -15.280 -38.145 36.821  1.00 33.91  ? 193 TYR B CE2 1 
ATOM   4969  C CZ  . TYR B 1 193 ? -16.140 -38.859 37.656  1.00 32.54  ? 193 TYR B CZ  1 
ATOM   4970  O OH  . TYR B 1 193 ? -17.400 -39.298 37.281  1.00 34.79  ? 193 TYR B OH  1 
ATOM   4971  N N   . LYS B 1 194 ? -10.332 -35.426 40.897  1.00 35.16  ? 194 LYS B N   1 
ATOM   4972  C CA  . LYS B 1 194 ? -8.935  -35.190 41.252  1.00 35.26  ? 194 LYS B CA  1 
ATOM   4973  C C   . LYS B 1 194 ? -8.777  -34.063 42.256  1.00 33.40  ? 194 LYS B C   1 
ATOM   4974  O O   . LYS B 1 194 ? -7.842  -33.261 42.152  1.00 36.86  ? 194 LYS B O   1 
ATOM   4975  C CB  . LYS B 1 194 ? -8.107  -34.812 40.019  1.00 37.48  ? 194 LYS B CB  1 
ATOM   4976  C CG  . LYS B 1 194 ? -8.001  -35.936 39.002  1.00 40.75  ? 194 LYS B CG  1 
ATOM   4977  C CD  . LYS B 1 194 ? -7.009  -36.974 39.435  1.00 44.70  ? 194 LYS B CD  1 
ATOM   4978  C CE  . LYS B 1 194 ? -7.474  -38.386 39.152  1.00 51.88  ? 194 LYS B CE  1 
ATOM   4979  N NZ  . LYS B 1 194 ? -6.513  -39.336 39.746  1.00 56.40  ? 194 LYS B NZ  1 
ATOM   4980  N N   . SER B 1 195 ? -9.693  -34.029 43.224  1.00 36.55  ? 195 SER B N   1 
ATOM   4981  C CA  . SER B 1 195 ? -9.618  -33.103 44.351  1.00 41.48  ? 195 SER B CA  1 
ATOM   4982  C C   . SER B 1 195 ? -9.813  -31.634 43.941  1.00 39.30  ? 195 SER B C   1 
ATOM   4983  O O   . SER B 1 195 ? -9.456  -30.746 44.707  1.00 34.98  ? 195 SER B O   1 
ATOM   4984  C CB  . SER B 1 195 ? -8.315  -33.295 45.116  1.00 37.85  ? 195 SER B CB  1 
ATOM   4985  O OG  . SER B 1 195 ? -8.317  -34.549 45.780  1.00 39.42  ? 195 SER B OG  1 
ATOM   4986  N N   . ASP B 1 196 ? -10.394 -31.375 42.758  1.00 37.20  ? 196 ASP B N   1 
ATOM   4987  C CA  . ASP B 1 196 ? -10.698 -30.015 42.339  1.00 36.35  ? 196 ASP B CA  1 
ATOM   4988  C C   . ASP B 1 196 ? -9.419  -29.170 42.414  1.00 37.37  ? 196 ASP B C   1 
ATOM   4989  O O   . ASP B 1 196 ? -9.456  -27.989 42.751  1.00 37.58  ? 196 ASP B O   1 
ATOM   4990  C CB  . ASP B 1 196 ? -11.861 -29.421 43.166  1.00 33.46  ? 196 ASP B CB  1 
ATOM   4991  C CG  . ASP B 1 196 ? -12.655 -28.282 42.515  1.00 37.06  ? 196 ASP B CG  1 
ATOM   4992  O OD1 . ASP B 1 196 ? -12.507 -28.038 41.262  1.00 34.59  ? 196 ASP B OD1 1 
ATOM   4993  O OD2 . ASP B 1 196 ? -13.443 -27.625 43.261  1.00 42.25  ? 196 ASP B OD2 1 
ATOM   4994  N N   . THR B 1 197 ? -8.271  -29.762 42.089  1.00 38.74  ? 197 THR B N   1 
ATOM   4995  C CA  . THR B 1 197 ? -7.106  -28.960 41.748  1.00 36.00  ? 197 THR B CA  1 
ATOM   4996  C C   . THR B 1 197 ? -6.870  -29.041 40.238  1.00 32.27  ? 197 THR B C   1 
ATOM   4997  O O   . THR B 1 197 ? -6.946  -30.111 39.638  1.00 38.24  ? 197 THR B O   1 
ATOM   4998  C CB  . THR B 1 197 ? -5.859  -29.385 42.538  1.00 36.53  ? 197 THR B CB  1 
ATOM   4999  O OG1 . THR B 1 197 ? -5.459  -30.649 42.020  1.00 36.59  ? 197 THR B OG1 1 
ATOM   5000  C CG2 . THR B 1 197 ? -6.101  -29.504 44.027  1.00 38.49  ? 197 THR B CG2 1 
ATOM   5001  N N   . HIS B 1 198 ? -6.488  -27.911 39.648  1.00 34.09  ? 198 HIS B N   1 
ATOM   5002  C CA  . HIS B 1 198 ? -6.511  -27.702 38.212  1.00 35.36  ? 198 HIS B CA  1 
ATOM   5003  C C   . HIS B 1 198 ? -5.112  -27.376 37.725  1.00 36.02  ? 198 HIS B C   1 
ATOM   5004  O O   . HIS B 1 198 ? -4.495  -26.451 38.224  1.00 39.32  ? 198 HIS B O   1 
ATOM   5005  C CB  . HIS B 1 198 ? -7.513  -26.573 37.875  1.00 36.08  ? 198 HIS B CB  1 
ATOM   5006  C CG  . HIS B 1 198 ? -8.906  -26.914 38.310  1.00 36.27  ? 198 HIS B CG  1 
ATOM   5007  N ND1 . HIS B 1 198 ? -9.806  -27.527 37.458  1.00 34.69  ? 198 HIS B ND1 1 
ATOM   5008  C CD2 . HIS B 1 198 ? -9.457  -26.919 39.568  1.00 30.44  ? 198 HIS B CD2 1 
ATOM   5009  C CE1 . HIS B 1 198 ? -10.902 -27.858 38.151  1.00 33.78  ? 198 HIS B CE1 1 
ATOM   5010  N NE2 . HIS B 1 198 ? -10.709 -27.489 39.470  1.00 30.34  ? 198 HIS B NE2 1 
ATOM   5011  N N   . ILE B 1 199 ? -4.656  -28.092 36.707  1.00 40.03  ? 199 ILE B N   1 
ATOM   5012  C CA  . ILE B 1 199 ? -3.420  -27.770 36.017  1.00 42.05  ? 199 ILE B CA  1 
ATOM   5013  C C   . ILE B 1 199 ? -3.762  -26.833 34.864  1.00 45.64  ? 199 ILE B C   1 
ATOM   5014  O O   . ILE B 1 199 ? -4.671  -27.121 34.073  1.00 53.08  ? 199 ILE B O   1 
ATOM   5015  C CB  . ILE B 1 199 ? -2.766  -29.080 35.537  1.00 46.10  ? 199 ILE B CB  1 
ATOM   5016  C CG1 . ILE B 1 199 ? -2.538  -30.019 36.720  1.00 43.44  ? 199 ILE B CG1 1 
ATOM   5017  C CG2 . ILE B 1 199 ? -1.510  -28.848 34.691  1.00 43.28  ? 199 ILE B CG2 1 
ATOM   5018  C CD1 . ILE B 1 199 ? -2.544  -31.491 36.337  1.00 47.96  ? 199 ILE B CD1 1 
ATOM   5019  N N   . PRO B 1 200 ? -3.091  -25.662 34.749  1.00 47.27  ? 200 PRO B N   1 
ATOM   5020  C CA  . PRO B 1 200 ? -3.382  -24.738 33.649  1.00 46.05  ? 200 PRO B CA  1 
ATOM   5021  C C   . PRO B 1 200 ? -2.961  -25.312 32.295  1.00 53.85  ? 200 PRO B C   1 
ATOM   5022  O O   . PRO B 1 200 ? -2.046  -26.158 32.180  1.00 53.09  ? 200 PRO B O   1 
ATOM   5023  C CB  . PRO B 1 200 ? -2.578  -23.468 33.982  1.00 45.29  ? 200 PRO B CB  1 
ATOM   5024  C CG  . PRO B 1 200 ? -1.492  -23.926 34.952  1.00 42.08  ? 200 PRO B CG  1 
ATOM   5025  C CD  . PRO B 1 200 ? -2.018  -25.179 35.638  1.00 43.91  ? 200 PRO B CD  1 
ATOM   5026  N N   . SER B 1 201 ? -3.661  -24.841 31.260  1.00 55.57  ? 201 SER B N   1 
ATOM   5027  C CA  . SER B 1 201 ? -3.313  -25.195 29.894  1.00 56.12  ? 201 SER B CA  1 
ATOM   5028  C C   . SER B 1 201 ? -1.918  -24.659 29.561  1.00 57.24  ? 201 SER B C   1 
ATOM   5029  O O   . SER B 1 201 ? -1.556  -23.550 29.974  1.00 52.81  ? 201 SER B O   1 
ATOM   5030  C CB  . SER B 1 201 ? -4.368  -24.708 28.920  1.00 49.06  ? 201 SER B CB  1 
ATOM   5031  O OG  . SER B 1 201 ? -3.791  -24.407 27.665  1.00 49.74  ? 201 SER B OG  1 
ATOM   5032  N N   . ASN B 1 202 ? -1.154  -25.480 28.821  1.00 60.29  ? 202 ASN B N   1 
ATOM   5033  C CA  . ASN B 1 202 ? 0.178   -25.147 28.342  1.00 63.18  ? 202 ASN B CA  1 
ATOM   5034  C C   . ASN B 1 202 ? 0.100   -24.705 26.882  1.00 65.49  ? 202 ASN B C   1 
ATOM   5035  O O   . ASN B 1 202 ? -0.151  -25.523 25.991  1.00 56.47  ? 202 ASN B O   1 
ATOM   5036  C CB  . ASN B 1 202 ? 1.128   -26.343 28.445  1.00 64.15  ? 202 ASN B CB  1 
ATOM   5037  C CG  . ASN B 1 202 ? 2.578   -25.988 28.218  1.00 61.32  ? 202 ASN B CG  1 
ATOM   5038  O OD1 . ASN B 1 202 ? 2.904   -24.912 27.724  1.00 63.43  ? 202 ASN B OD1 1 
ATOM   5039  N ND2 . ASN B 1 202 ? 3.459   -26.891 28.611  1.00 65.03  ? 202 ASN B ND2 1 
ATOM   5040  N N   . PRO B 1 203 ? 0.350   -23.408 26.578  1.00 66.91  ? 203 PRO B N   1 
ATOM   5041  C CA  . PRO B 1 203 ? 0.302   -22.923 25.193  1.00 67.83  ? 203 PRO B CA  1 
ATOM   5042  C C   . PRO B 1 203 ? 1.308   -23.553 24.216  1.00 69.69  ? 203 PRO B C   1 
ATOM   5043  O O   . PRO B 1 203 ? 1.221   -23.343 23.015  1.00 61.34  ? 203 PRO B O   1 
ATOM   5044  C CB  . PRO B 1 203 ? 0.581   -21.421 25.352  1.00 64.73  ? 203 PRO B CB  1 
ATOM   5045  C CG  . PRO B 1 203 ? 1.373   -21.339 26.642  1.00 64.98  ? 203 PRO B CG  1 
ATOM   5046  C CD  . PRO B 1 203 ? 0.711   -22.355 27.540  1.00 59.75  ? 203 PRO B CD  1 
ATOM   5047  N N   . ASP B 1 204 ? 2.267   -24.337 24.718  1.00 73.07  ? 204 ASP B N   1 
ATOM   5048  C CA  . ASP B 1 204 ? 3.290   -24.932 23.873  1.00 73.14  ? 204 ASP B CA  1 
ATOM   5049  C C   . ASP B 1 204 ? 2.883   -26.339 23.436  1.00 74.12  ? 204 ASP B C   1 
ATOM   5050  O O   . ASP B 1 204 ? 3.679   -27.024 22.800  1.00 83.87  ? 204 ASP B O   1 
ATOM   5051  C CB  . ASP B 1 204 ? 4.655   -24.979 24.586  1.00 77.61  ? 204 ASP B CB  1 
ATOM   5052  C CG  . ASP B 1 204 ? 5.231   -23.622 24.985  1.00 80.07  ? 204 ASP B CG  1 
ATOM   5053  O OD1 . ASP B 1 204 ? 5.235   -22.692 24.130  1.00 79.47  ? 204 ASP B OD1 1 
ATOM   5054  O OD2 . ASP B 1 204 ? 5.702   -23.507 26.143  1.00 75.19  ? 204 ASP B OD2 1 
ATOM   5055  N N   . LEU B 1 205 ? 1.656   -26.776 23.760  1.00 71.73  ? 205 LEU B N   1 
ATOM   5056  C CA  . LEU B 1 205 ? 1.260   -28.163 23.536  1.00 65.24  ? 205 LEU B CA  1 
ATOM   5057  C C   . LEU B 1 205 ? 0.149   -28.239 22.486  1.00 61.57  ? 205 LEU B C   1 
ATOM   5058  O O   . LEU B 1 205 ? -0.670  -27.330 22.343  1.00 56.05  ? 205 LEU B O   1 
ATOM   5059  C CB  . LEU B 1 205 ? 0.810   -28.784 24.863  1.00 64.44  ? 205 LEU B CB  1 
ATOM   5060  C CG  . LEU B 1 205 ? 1.910   -29.307 25.800  1.00 62.70  ? 205 LEU B CG  1 
ATOM   5061  C CD1 . LEU B 1 205 ? 1.295   -29.941 27.046  1.00 59.54  ? 205 LEU B CD1 1 
ATOM   5062  C CD2 . LEU B 1 205 ? 2.827   -30.317 25.098  1.00 54.95  ? 205 LEU B CD2 1 
ATOM   5063  N N   . ASP B 1 206 ? 0.118   -29.343 21.739  1.00 64.13  ? 206 ASP B N   1 
ATOM   5064  C CA  . ASP B 1 206 ? -0.998  -29.597 20.843  1.00 64.42  ? 206 ASP B CA  1 
ATOM   5065  C C   . ASP B 1 206 ? -2.227  -29.970 21.685  1.00 70.02  ? 206 ASP B C   1 
ATOM   5066  O O   . ASP B 1 206 ? -2.134  -30.177 22.900  1.00 63.44  ? 206 ASP B O   1 
ATOM   5067  C CB  . ASP B 1 206 ? -0.652  -30.684 19.827  1.00 55.39  ? 206 ASP B CB  1 
ATOM   5068  C CG  . ASP B 1 206 ? -0.751  -32.107 20.360  1.00 66.42  ? 206 ASP B CG  1 
ATOM   5069  O OD1 . ASP B 1 206 ? 0.216   -32.520 21.060  1.00 59.27  ? 206 ASP B OD1 1 
ATOM   5070  O OD2 . ASP B 1 206 ? -1.804  -32.801 20.066  1.00 71.07  ? 206 ASP B OD2 1 
ATOM   5071  N N   . LEU B 1 207 ? -3.380  -30.086 21.014  1.00 67.13  ? 207 LEU B N   1 
ATOM   5072  C CA  . LEU B 1 207 ? -4.656  -30.359 21.653  1.00 63.30  ? 207 LEU B CA  1 
ATOM   5073  C C   . LEU B 1 207 ? -4.583  -31.616 22.530  1.00 61.95  ? 207 LEU B C   1 
ATOM   5074  O O   . LEU B 1 207 ? -4.901  -31.573 23.722  1.00 58.48  ? 207 LEU B O   1 
ATOM   5075  C CB  . LEU B 1 207 ? -5.701  -30.472 20.540  1.00 61.53  ? 207 LEU B CB  1 
ATOM   5076  C CG  . LEU B 1 207 ? -7.135  -30.642 21.033  1.00 64.24  ? 207 LEU B CG  1 
ATOM   5077  C CD1 . LEU B 1 207 ? -8.135  -30.115 20.017  1.00 62.05  ? 207 LEU B CD1 1 
ATOM   5078  C CD2 . LEU B 1 207 ? -7.412  -32.106 21.364  1.00 67.60  ? 207 LEU B CD2 1 
ATOM   5079  N N   . GLY B 1 208 ? -4.132  -32.730 21.946  1.00 55.04  ? 208 GLY B N   1 
ATOM   5080  C CA  . GLY B 1 208 ? -3.990  -33.983 22.670  1.00 48.22  ? 208 GLY B CA  1 
ATOM   5081  C C   . GLY B 1 208 ? -2.975  -33.903 23.805  1.00 48.18  ? 208 GLY B C   1 
ATOM   5082  O O   . GLY B 1 208 ? -3.202  -34.431 24.888  1.00 58.45  ? 208 GLY B O   1 
ATOM   5083  N N   . GLY B 1 209 ? -1.821  -33.282 23.551  1.00 51.54  ? 209 GLY B N   1 
ATOM   5084  C CA  . GLY B 1 209 ? -0.806  -33.125 24.580  1.00 45.69  ? 209 GLY B CA  1 
ATOM   5085  C C   . GLY B 1 209 ? -1.340  -32.267 25.719  1.00 50.08  ? 209 GLY B C   1 
ATOM   5086  O O   . GLY B 1 209 ? -1.136  -32.574 26.895  1.00 53.19  ? 209 GLY B O   1 
ATOM   5087  N N   . ASP B 1 210 ? -2.063  -31.201 25.356  1.00 48.77  ? 210 ASP B N   1 
ATOM   5088  C CA  . ASP B 1 210 ? -2.547  -30.269 26.356  1.00 51.47  ? 210 ASP B CA  1 
ATOM   5089  C C   . ASP B 1 210 ? -3.661  -30.904 27.207  1.00 50.50  ? 210 ASP B C   1 
ATOM   5090  O O   . ASP B 1 210 ? -3.809  -30.583 28.393  1.00 45.88  ? 210 ASP B O   1 
ATOM   5091  C CB  . ASP B 1 210 ? -2.987  -28.959 25.716  1.00 51.49  ? 210 ASP B CB  1 
ATOM   5092  C CG  . ASP B 1 210 ? -3.303  -27.937 26.787  1.00 62.68  ? 210 ASP B CG  1 
ATOM   5093  O OD1 . ASP B 1 210 ? -2.558  -27.936 27.806  1.00 59.28  ? 210 ASP B OD1 1 
ATOM   5094  O OD2 . ASP B 1 210 ? -4.284  -27.173 26.612  1.00 66.91  ? 210 ASP B OD2 1 
ATOM   5095  N N   . PHE B 1 211 ? -4.444  -31.801 26.598  1.00 40.15  ? 211 PHE B N   1 
ATOM   5096  C CA  . PHE B 1 211 ? -5.494  -32.487 27.309  1.00 40.99  ? 211 PHE B CA  1 
ATOM   5097  C C   . PHE B 1 211 ? -4.889  -33.359 28.409  1.00 40.49  ? 211 PHE B C   1 
ATOM   5098  O O   . PHE B 1 211 ? -5.267  -33.254 29.580  1.00 42.79  ? 211 PHE B O   1 
ATOM   5099  C CB  . PHE B 1 211 ? -6.360  -33.245 26.301  1.00 43.06  ? 211 PHE B CB  1 
ATOM   5100  C CG  . PHE B 1 211 ? -7.469  -34.032 26.947  1.00 46.71  ? 211 PHE B CG  1 
ATOM   5101  C CD1 . PHE B 1 211 ? -8.577  -33.382 27.484  1.00 47.09  ? 211 PHE B CD1 1 
ATOM   5102  C CD2 . PHE B 1 211 ? -7.358  -35.408 27.092  1.00 42.88  ? 211 PHE B CD2 1 
ATOM   5103  C CE1 . PHE B 1 211 ? -9.582  -34.103 28.103  1.00 50.39  ? 211 PHE B CE1 1 
ATOM   5104  C CE2 . PHE B 1 211 ? -8.356  -36.128 27.724  1.00 45.11  ? 211 PHE B CE2 1 
ATOM   5105  C CZ  . PHE B 1 211 ? -9.466  -35.475 28.223  1.00 52.02  ? 211 PHE B CZ  1 
ATOM   5106  N N   . ALA B 1 212 ? -3.926  -34.204 28.031  1.00 40.75  ? 212 ALA B N   1 
ATOM   5107  C CA  . ALA B 1 212 ? -3.243  -35.094 28.967  1.00 44.04  ? 212 ALA B CA  1 
ATOM   5108  C C   . ALA B 1 212 ? -2.620  -34.292 30.115  1.00 46.77  ? 212 ALA B C   1 
ATOM   5109  O O   . ALA B 1 212 ? -2.604  -34.740 31.260  1.00 46.32  ? 212 ALA B O   1 
ATOM   5110  C CB  . ALA B 1 212 ? -2.181  -35.883 28.224  1.00 44.09  ? 212 ALA B CB  1 
ATOM   5111  N N   . ASN B 1 213 ? -2.062  -33.127 29.764  1.00 46.31  ? 213 ASN B N   1 
ATOM   5112  C CA  . ASN B 1 213 ? -1.501  -32.166 30.700  1.00 48.11  ? 213 ASN B CA  1 
ATOM   5113  C C   . ASN B 1 213 ? -2.552  -31.755 31.738  1.00 45.09  ? 213 ASN B C   1 
ATOM   5114  O O   . ASN B 1 213 ? -2.374  -31.954 32.939  1.00 44.46  ? 213 ASN B O   1 
ATOM   5115  C CB  . ASN B 1 213 ? -0.944  -30.966 29.913  1.00 49.26  ? 213 ASN B CB  1 
ATOM   5116  C CG  . ASN B 1 213 ? -0.537  -29.792 30.777  1.00 53.36  ? 213 ASN B CG  1 
ATOM   5117  O OD1 . ASN B 1 213 ? 0.437   -29.892 31.532  1.00 48.96  ? 213 ASN B OD1 1 
ATOM   5118  N ND2 . ASN B 1 213 ? -1.263  -28.684 30.658  1.00 55.60  ? 213 ASN B ND2 1 
ATOM   5119  N N   . MET B 1 214 ? -3.670  -31.208 31.259  1.00 40.49  ? 214 MET B N   1 
ATOM   5120  C CA  . MET B 1 214 ? -4.716  -30.717 32.132  1.00 40.88  ? 214 MET B CA  1 
ATOM   5121  C C   . MET B 1 214 ? -5.372  -31.858 32.907  1.00 40.03  ? 214 MET B C   1 
ATOM   5122  O O   . MET B 1 214 ? -5.932  -31.644 33.980  1.00 42.31  ? 214 MET B O   1 
ATOM   5123  C CB  . MET B 1 214 ? -5.777  -30.002 31.300  1.00 42.72  ? 214 MET B CB  1 
ATOM   5124  C CG  . MET B 1 214 ? -5.217  -28.807 30.571  1.00 49.54  ? 214 MET B CG  1 
ATOM   5125  S SD  . MET B 1 214 ? -6.437  -27.930 29.597  1.00 54.71  ? 214 MET B SD  1 
ATOM   5126  C CE  . MET B 1 214 ? -6.792  -26.607 30.750  1.00 52.38  ? 214 MET B CE  1 
ATOM   5127  N N   . MET B 1 215 ? -5.342  -33.064 32.345  1.00 39.79  ? 215 MET B N   1 
ATOM   5128  C CA  . MET B 1 215 ? -5.893  -34.222 33.024  1.00 40.26  ? 215 MET B CA  1 
ATOM   5129  C C   . MET B 1 215 ? -4.972  -34.652 34.158  1.00 36.33  ? 215 MET B C   1 
ATOM   5130  O O   . MET B 1 215 ? -5.412  -35.278 35.127  1.00 34.40  ? 215 MET B O   1 
ATOM   5131  C CB  . MET B 1 215 ? -6.070  -35.382 32.039  1.00 45.07  ? 215 MET B CB  1 
ATOM   5132  C CG  . MET B 1 215 ? -7.219  -35.147 31.079  1.00 44.67  ? 215 MET B CG  1 
ATOM   5133  S SD  . MET B 1 215 ? -8.847  -35.539 31.788  1.00 49.82  ? 215 MET B SD  1 
ATOM   5134  C CE  . MET B 1 215 ? -8.671  -37.308 32.001  1.00 49.54  ? 215 MET B CE  1 
ATOM   5135  N N   . GLY B 1 216 ? -3.683  -34.354 33.984  1.00 39.23  ? 216 GLY B N   1 
ATOM   5136  C CA  . GLY B 1 216 ? -2.651  -34.708 34.945  1.00 44.64  ? 216 GLY B CA  1 
ATOM   5137  C C   . GLY B 1 216 ? -2.055  -36.097 34.691  1.00 49.59  ? 216 GLY B C   1 
ATOM   5138  O O   . GLY B 1 216 ? -1.631  -36.770 35.629  1.00 61.66  ? 216 GLY B O   1 
ATOM   5139  N N   . ILE B 1 217 ? -1.997  -36.530 33.421  1.00 51.32  ? 217 ILE B N   1 
ATOM   5140  C CA  . ILE B 1 217 ? -1.589  -37.890 33.108  1.00 51.95  ? 217 ILE B CA  1 
ATOM   5141  C C   . ILE B 1 217 ? -0.366  -37.818 32.198  1.00 55.59  ? 217 ILE B C   1 
ATOM   5142  O O   . ILE B 1 217 ? -0.339  -37.042 31.247  1.00 58.50  ? 217 ILE B O   1 
ATOM   5143  C CB  . ILE B 1 217 ? -2.770  -38.691 32.512  1.00 53.74  ? 217 ILE B CB  1 
ATOM   5144  C CG1 . ILE B 1 217 ? -4.013  -38.605 33.410  1.00 52.73  ? 217 ILE B CG1 1 
ATOM   5145  C CG2 . ILE B 1 217 ? -2.390  -40.149 32.261  1.00 55.96  ? 217 ILE B CG2 1 
ATOM   5146  C CD1 . ILE B 1 217 ? -5.232  -39.358 32.902  1.00 51.54  ? 217 ILE B CD1 1 
ATOM   5147  N N   . ASP B 1 218 ? 0.657   -38.621 32.520  1.00 57.23  ? 218 ASP B N   1 
ATOM   5148  C CA  . ASP B 1 218 ? 1.937   -38.550 31.832  1.00 63.32  ? 218 ASP B CA  1 
ATOM   5149  C C   . ASP B 1 218 ? 1.894   -39.352 30.543  1.00 66.17  ? 218 ASP B C   1 
ATOM   5150  O O   . ASP B 1 218 ? 0.984   -40.152 30.334  1.00 67.68  ? 218 ASP B O   1 
ATOM   5151  C CB  . ASP B 1 218 ? 3.099   -39.041 32.703  1.00 74.55  ? 218 ASP B CB  1 
ATOM   5152  C CG  . ASP B 1 218 ? 3.435   -38.101 33.869  1.00 86.30  ? 218 ASP B CG  1 
ATOM   5153  O OD1 . ASP B 1 218 ? 3.648   -36.883 33.636  1.00 85.05  ? 218 ASP B OD1 1 
ATOM   5154  O OD2 . ASP B 1 218 ? 3.493   -38.582 35.021  1.00 92.81  ? 218 ASP B OD2 1 
ATOM   5155  N N   . LYS B 1 219 ? 2.918   -39.115 29.703  1.00 74.50  ? 219 LYS B N   1 
ATOM   5156  C CA  . LYS B 1 219 ? 3.152   -39.851 28.464  1.00 66.81  ? 219 LYS B CA  1 
ATOM   5157  C C   . LYS B 1 219 ? 3.149   -41.346 28.779  1.00 61.64  ? 219 LYS B C   1 
ATOM   5158  O O   . LYS B 1 219 ? 3.648   -41.767 29.822  1.00 57.63  ? 219 LYS B O   1 
ATOM   5159  C CB  . LYS B 1 219 ? 4.507   -39.518 27.818  1.00 66.55  ? 219 LYS B CB  1 
ATOM   5160  C CG  . LYS B 1 219 ? 4.751   -38.105 27.289  1.00 68.71  ? 219 LYS B CG  1 
ATOM   5161  C CD  . LYS B 1 219 ? 5.075   -37.055 28.376  1.00 83.81  ? 219 LYS B CD  1 
ATOM   5162  C CE  . LYS B 1 219 ? 6.209   -36.103 28.056  1.00 90.10  ? 219 LYS B CE  1 
ATOM   5163  N NZ  . LYS B 1 219 ? 6.196   -35.666 26.641  1.00 91.99  ? 219 LYS B NZ  1 
ATOM   5164  N N   . PRO B 1 220 ? 2.604   -42.215 27.903  1.00 63.51  ? 220 PRO B N   1 
ATOM   5165  C CA  . PRO B 1 220 ? 2.075   -41.814 26.595  1.00 63.65  ? 220 PRO B CA  1 
ATOM   5166  C C   . PRO B 1 220 ? 0.576   -41.516 26.524  1.00 64.68  ? 220 PRO B C   1 
ATOM   5167  O O   . PRO B 1 220 ? -0.041  -41.711 25.473  1.00 65.93  ? 220 PRO B O   1 
ATOM   5168  C CB  . PRO B 1 220 ? 2.349   -43.109 25.820  1.00 65.34  ? 220 PRO B CB  1 
ATOM   5169  C CG  . PRO B 1 220 ? 1.988   -44.216 26.823  1.00 65.89  ? 220 PRO B CG  1 
ATOM   5170  C CD  . PRO B 1 220 ? 2.465   -43.668 28.154  1.00 64.32  ? 220 PRO B CD  1 
ATOM   5171  N N   . TYR B 1 221 ? -0.021  -41.045 27.629  1.00 55.97  ? 221 TYR B N   1 
ATOM   5172  C CA  . TYR B 1 221 ? -1.439  -40.734 27.591  1.00 54.09  ? 221 TYR B CA  1 
ATOM   5173  C C   . TYR B 1 221 ? -1.729  -39.709 26.491  1.00 48.62  ? 221 TYR B C   1 
ATOM   5174  O O   . TYR B 1 221 ? -2.790  -39.740 25.872  1.00 49.17  ? 221 TYR B O   1 
ATOM   5175  C CB  . TYR B 1 221 ? -1.966  -40.273 28.955  1.00 55.82  ? 221 TYR B CB  1 
ATOM   5176  C CG  . TYR B 1 221 ? -3.476  -40.272 28.992  1.00 55.71  ? 221 TYR B CG  1 
ATOM   5177  C CD1 . TYR B 1 221 ? -4.179  -41.470 29.058  1.00 57.52  ? 221 TYR B CD1 1 
ATOM   5178  C CD2 . TYR B 1 221 ? -4.204  -39.098 28.852  1.00 52.58  ? 221 TYR B CD2 1 
ATOM   5179  C CE1 . TYR B 1 221 ? -5.565  -41.497 29.029  1.00 59.21  ? 221 TYR B CE1 1 
ATOM   5180  C CE2 . TYR B 1 221 ? -5.590  -39.110 28.817  1.00 54.16  ? 221 TYR B CE2 1 
ATOM   5181  C CZ  . TYR B 1 221 ? -6.273  -40.313 28.893  1.00 58.48  ? 221 TYR B CZ  1 
ATOM   5182  O OH  . TYR B 1 221 ? -7.643  -40.344 28.830  1.00 59.92  ? 221 TYR B OH  1 
ATOM   5183  N N   . ASP B 1 222 ? -0.789  -38.790 26.251  1.00 50.44  ? 222 ASP B N   1 
ATOM   5184  C CA  . ASP B 1 222 ? -0.902  -37.839 25.155  1.00 52.50  ? 222 ASP B CA  1 
ATOM   5185  C C   . ASP B 1 222 ? -1.252  -38.584 23.864  1.00 51.23  ? 222 ASP B C   1 
ATOM   5186  O O   . ASP B 1 222 ? -2.113  -38.136 23.108  1.00 55.79  ? 222 ASP B O   1 
ATOM   5187  C CB  . ASP B 1 222 ? 0.371   -36.982 25.023  1.00 60.75  ? 222 ASP B CB  1 
ATOM   5188  C CG  . ASP B 1 222 ? 1.691   -37.725 24.766  1.00 70.33  ? 222 ASP B CG  1 
ATOM   5189  O OD1 . ASP B 1 222 ? 1.878   -38.856 25.321  1.00 73.46  ? 222 ASP B OD1 1 
ATOM   5190  O OD2 . ASP B 1 222 ? 2.574   -37.149 24.048  1.00 56.31  ? 222 ASP B OD2 1 
ATOM   5191  N N   . ASP B 1 223 ? -0.593  -39.722 23.602  1.00 47.04  ? 223 ASP B N   1 
ATOM   5192  C CA  . ASP B 1 223 ? -0.808  -40.434 22.349  1.00 52.86  ? 223 ASP B CA  1 
ATOM   5193  C C   . ASP B 1 223 ? -2.125  -41.206 22.377  1.00 51.26  ? 223 ASP B C   1 
ATOM   5194  O O   . ASP B 1 223 ? -2.838  -41.249 21.374  1.00 43.46  ? 223 ASP B O   1 
ATOM   5195  C CB  . ASP B 1 223 ? 0.361   -41.367 22.031  1.00 59.78  ? 223 ASP B CB  1 
ATOM   5196  C CG  . ASP B 1 223 ? 1.535   -40.676 21.360  1.00 62.75  ? 223 ASP B CG  1 
ATOM   5197  O OD1 . ASP B 1 223 ? 1.338   -39.570 20.789  1.00 70.40  ? 223 ASP B OD1 1 
ATOM   5198  O OD2 . ASP B 1 223 ? 2.642   -41.238 21.436  1.00 57.56  ? 223 ASP B OD2 1 
ATOM   5199  N N   . VAL B 1 224 ? -2.409  -41.821 23.528  1.00 48.85  ? 224 VAL B N   1 
ATOM   5200  C CA  . VAL B 1 224 ? -3.693  -42.437 23.821  1.00 48.93  ? 224 VAL B CA  1 
ATOM   5201  C C   . VAL B 1 224 ? -4.832  -41.486 23.475  1.00 47.98  ? 224 VAL B C   1 
ATOM   5202  O O   . VAL B 1 224 ? -5.819  -41.922 22.904  1.00 45.12  ? 224 VAL B O   1 
ATOM   5203  C CB  . VAL B 1 224 ? -3.791  -42.823 25.308  1.00 53.87  ? 224 VAL B CB  1 
ATOM   5204  C CG1 . VAL B 1 224 ? -5.182  -43.330 25.659  1.00 57.20  ? 224 VAL B CG1 1 
ATOM   5205  C CG2 . VAL B 1 224 ? -2.726  -43.837 25.719  1.00 53.83  ? 224 VAL B CG2 1 
ATOM   5206  N N   . ALA B 1 225 ? -4.706  -40.215 23.885  1.00 54.08  ? 225 ALA B N   1 
ATOM   5207  C CA  . ALA B 1 225 ? -5.734  -39.190 23.701  1.00 58.61  ? 225 ALA B CA  1 
ATOM   5208  C C   . ALA B 1 225 ? -5.913  -38.824 22.233  1.00 53.19  ? 225 ALA B C   1 
ATOM   5209  O O   . ALA B 1 225 ? -7.041  -38.770 21.752  1.00 50.22  ? 225 ALA B O   1 
ATOM   5210  C CB  . ALA B 1 225 ? -5.384  -37.943 24.476  1.00 59.61  ? 225 ALA B CB  1 
ATOM   5211  N N   . ARG B 1 226 ? -4.791  -38.533 21.558  1.00 53.79  ? 226 ARG B N   1 
ATOM   5212  C CA  . ARG B 1 226 ? -4.776  -38.247 20.131  1.00 52.35  ? 226 ARG B CA  1 
ATOM   5213  C C   . ARG B 1 226 ? -5.473  -39.370 19.357  1.00 54.22  ? 226 ARG B C   1 
ATOM   5214  O O   . ARG B 1 226 ? -6.412  -39.145 18.588  1.00 54.07  ? 226 ARG B O   1 
ATOM   5215  C CB  . ARG B 1 226 ? -3.334  -38.085 19.648  1.00 53.02  ? 226 ARG B CB  1 
ATOM   5216  C CG  . ARG B 1 226 ? -2.669  -36.799 20.107  1.00 54.16  ? 226 ARG B CG  1 
ATOM   5217  C CD  . ARG B 1 226 ? -1.156  -36.925 20.064  1.00 54.69  ? 226 ARG B CD  1 
ATOM   5218  N NE  . ARG B 1 226 ? -0.465  -35.753 20.580  1.00 54.58  ? 226 ARG B NE  1 
ATOM   5219  C CZ  . ARG B 1 226 ? 0.611   -35.791 21.370  1.00 58.42  ? 226 ARG B CZ  1 
ATOM   5220  N NH1 . ARG B 1 226 ? 1.200   -36.940 21.666  1.00 50.88  ? 226 ARG B NH1 1 
ATOM   5221  N NH2 . ARG B 1 226 ? 1.131   -34.661 21.820  1.00 60.33  ? 226 ARG B NH2 1 
ATOM   5222  N N   . LEU B 1 227 ? -5.010  -40.600 19.562  1.00 51.42  ? 227 LEU B N   1 
ATOM   5223  C CA  . LEU B 1 227 ? -5.602  -41.719 18.864  1.00 51.33  ? 227 LEU B CA  1 
ATOM   5224  C C   . LEU B 1 227 ? -7.106  -41.757 19.135  1.00 51.86  ? 227 LEU B C   1 
ATOM   5225  O O   . LEU B 1 227 ? -7.903  -41.765 18.203  1.00 47.98  ? 227 LEU B O   1 
ATOM   5226  C CB  . LEU B 1 227 ? -4.920  -42.999 19.341  1.00 54.25  ? 227 LEU B CB  1 
ATOM   5227  C CG  . LEU B 1 227 ? -5.518  -44.278 18.764  1.00 63.12  ? 227 LEU B CG  1 
ATOM   5228  C CD1 . LEU B 1 227 ? -5.436  -44.258 17.239  1.00 65.17  ? 227 LEU B CD1 1 
ATOM   5229  C CD2 . LEU B 1 227 ? -4.822  -45.506 19.337  1.00 70.21  ? 227 LEU B CD2 1 
ATOM   5230  N N   . TYR B 1 228 ? -7.471  -41.782 20.422  1.00 52.11  ? 228 TYR B N   1 
ATOM   5231  C CA  . TYR B 1 228 ? -8.847  -41.986 20.840  1.00 50.55  ? 228 TYR B CA  1 
ATOM   5232  C C   . TYR B 1 228 ? -9.747  -40.956 20.166  1.00 45.09  ? 228 TYR B C   1 
ATOM   5233  O O   . TYR B 1 228 ? -10.840 -41.290 19.716  1.00 41.61  ? 228 TYR B O   1 
ATOM   5234  C CB  . TYR B 1 228 ? -8.974  -41.925 22.370  1.00 57.27  ? 228 TYR B CB  1 
ATOM   5235  C CG  . TYR B 1 228 ? -10.378 -42.106 22.896  1.00 64.06  ? 228 TYR B CG  1 
ATOM   5236  C CD1 . TYR B 1 228 ? -11.334 -41.118 22.725  1.00 68.32  ? 228 TYR B CD1 1 
ATOM   5237  C CD2 . TYR B 1 228 ? -10.773 -43.286 23.504  1.00 68.17  ? 228 TYR B CD2 1 
ATOM   5238  C CE1 . TYR B 1 228 ? -12.639 -41.290 23.154  1.00 70.43  ? 228 TYR B CE1 1 
ATOM   5239  C CE2 . TYR B 1 228 ? -12.076 -43.473 23.947  1.00 72.38  ? 228 TYR B CE2 1 
ATOM   5240  C CZ  . TYR B 1 228 ? -13.016 -42.470 23.773  1.00 72.25  ? 228 TYR B CZ  1 
ATOM   5241  O OH  . TYR B 1 228 ? -14.324 -42.623 24.194  1.00 74.69  ? 228 TYR B OH  1 
ATOM   5242  N N   . PHE B 1 229 ? -9.305  -39.697 20.126  1.00 44.15  ? 229 PHE B N   1 
ATOM   5243  C CA  . PHE B 1 229 ? -10.163 -38.645 19.605  1.00 50.02  ? 229 PHE B CA  1 
ATOM   5244  C C   . PHE B 1 229 ? -10.333 -38.810 18.103  1.00 53.53  ? 229 PHE B C   1 
ATOM   5245  O O   . PHE B 1 229 ? -11.414 -38.567 17.573  1.00 57.53  ? 229 PHE B O   1 
ATOM   5246  C CB  . PHE B 1 229 ? -9.585  -37.261 19.908  1.00 49.17  ? 229 PHE B CB  1 
ATOM   5247  C CG  . PHE B 1 229 ? -9.618  -36.847 21.359  1.00 47.80  ? 229 PHE B CG  1 
ATOM   5248  C CD1 . PHE B 1 229 ? -10.562 -37.368 22.244  1.00 45.13  ? 229 PHE B CD1 1 
ATOM   5249  C CD2 . PHE B 1 229 ? -8.663  -35.957 21.844  1.00 45.18  ? 229 PHE B CD2 1 
ATOM   5250  C CE1 . PHE B 1 229 ? -10.561 -36.993 23.581  1.00 47.26  ? 229 PHE B CE1 1 
ATOM   5251  C CE2 . PHE B 1 229 ? -8.660  -35.585 23.180  1.00 46.38  ? 229 PHE B CE2 1 
ATOM   5252  C CZ  . PHE B 1 229 ? -9.612  -36.098 24.045  1.00 48.32  ? 229 PHE B CZ  1 
ATOM   5253  N N   . ILE B 1 230 ? -9.243  -39.208 17.434  1.00 57.30  ? 230 ILE B N   1 
ATOM   5254  C CA  . ILE B 1 230 ? -9.261  -39.429 15.996  1.00 56.09  ? 230 ILE B CA  1 
ATOM   5255  C C   . ILE B 1 230 ? -10.194 -40.603 15.673  1.00 47.15  ? 230 ILE B C   1 
ATOM   5256  O O   . ILE B 1 230 ? -11.059 -40.462 14.818  1.00 39.31  ? 230 ILE B O   1 
ATOM   5257  C CB  . ILE B 1 230 ? -7.825  -39.589 15.437  1.00 63.85  ? 230 ILE B CB  1 
ATOM   5258  C CG1 . ILE B 1 230 ? -7.085  -38.247 15.402  1.00 63.45  ? 230 ILE B CG1 1 
ATOM   5259  C CG2 . ILE B 1 230 ? -7.836  -40.200 14.041  1.00 66.49  ? 230 ILE B CG2 1 
ATOM   5260  C CD1 . ILE B 1 230 ? -5.577  -38.366 15.437  1.00 64.59  ? 230 ILE B CD1 1 
ATOM   5261  N N   . LEU B 1 231 ? -10.075 -41.723 16.398  1.00 41.68  ? 231 LEU B N   1 
ATOM   5262  C CA  . LEU B 1 231 ? -10.919 -42.886 16.158  1.00 49.52  ? 231 LEU B CA  1 
ATOM   5263  C C   . LEU B 1 231 ? -12.407 -42.572 16.344  1.00 49.33  ? 231 LEU B C   1 
ATOM   5264  O O   . LEU B 1 231 ? -13.256 -43.056 15.579  1.00 50.00  ? 231 LEU B O   1 
ATOM   5265  C CB  . LEU B 1 231 ? -10.489 -44.016 17.101  1.00 49.09  ? 231 LEU B CB  1 
ATOM   5266  C CG  . LEU B 1 231 ? -9.073  -44.549 16.901  1.00 52.15  ? 231 LEU B CG  1 
ATOM   5267  C CD1 . LEU B 1 231 ? -8.927  -45.941 17.518  1.00 55.70  ? 231 LEU B CD1 1 
ATOM   5268  C CD2 . LEU B 1 231 ? -8.680  -44.572 15.424  1.00 55.34  ? 231 LEU B CD2 1 
ATOM   5269  N N   . HIS B 1 232 ? -12.717 -41.748 17.353  1.00 44.25  ? 232 HIS B N   1 
ATOM   5270  C CA  . HIS B 1 232 ? -14.111 -41.484 17.680  1.00 44.01  ? 232 HIS B CA  1 
ATOM   5271  C C   . HIS B 1 232 ? -14.608 -40.208 16.988  1.00 38.60  ? 232 HIS B C   1 
ATOM   5272  O O   . HIS B 1 232 ? -15.717 -39.771 17.255  1.00 36.87  ? 232 HIS B O   1 
ATOM   5273  C CB  . HIS B 1 232 ? -14.303 -41.417 19.201  1.00 46.80  ? 232 HIS B CB  1 
ATOM   5274  C CG  . HIS B 1 232 ? -14.066 -42.701 19.940  1.00 53.50  ? 232 HIS B CG  1 
ATOM   5275  N ND1 . HIS B 1 232 ? -12.812 -43.196 20.248  1.00 55.15  ? 232 HIS B ND1 1 
ATOM   5276  C CD2 . HIS B 1 232 ? -14.988 -43.558 20.484  1.00 57.21  ? 232 HIS B CD2 1 
ATOM   5277  C CE1 . HIS B 1 232 ? -12.954 -44.344 20.913  1.00 52.84  ? 232 HIS B CE1 1 
ATOM   5278  N NE2 . HIS B 1 232 ? -14.295 -44.595 21.062  1.00 54.08  ? 232 HIS B NE2 1 
ATOM   5279  N N   . SER B 1 233 ? -13.834 -39.664 16.040  1.00 37.76  ? 233 SER B N   1 
ATOM   5280  C CA  . SER B 1 233 ? -14.119 -38.371 15.434  1.00 41.45  ? 233 SER B CA  1 
ATOM   5281  C C   . SER B 1 233 ? -15.403 -38.369 14.611  1.00 40.65  ? 233 SER B C   1 
ATOM   5282  O O   . SER B 1 233 ? -16.105 -37.364 14.605  1.00 43.03  ? 233 SER B O   1 
ATOM   5283  C CB  . SER B 1 233 ? -12.961 -37.889 14.590  1.00 43.61  ? 233 SER B CB  1 
ATOM   5284  O OG  . SER B 1 233 ? -12.585 -38.873 13.644  1.00 47.72  ? 233 SER B OG  1 
ATOM   5285  N N   . ASP B 1 234 ? -15.668 -39.431 13.848  1.00 45.59  ? 234 ASP B N   1 
ATOM   5286  C CA  . ASP B 1 234 ? -16.928 -39.505 13.126  1.00 59.61  ? 234 ASP B CA  1 
ATOM   5287  C C   . ASP B 1 234 ? -17.255 -40.976 12.901  1.00 59.16  ? 234 ASP B C   1 
ATOM   5288  O O   . ASP B 1 234 ? -16.396 -41.841 13.119  1.00 52.19  ? 234 ASP B O   1 
ATOM   5289  C CB  . ASP B 1 234 ? -16.950 -38.656 11.840  1.00 70.22  ? 234 ASP B CB  1 
ATOM   5290  C CG  . ASP B 1 234 ? -18.305 -38.028 11.464  1.00 88.22  ? 234 ASP B CG  1 
ATOM   5291  O OD1 . ASP B 1 234 ? -19.007 -37.439 12.375  1.00 86.14  ? 234 ASP B OD1 1 
ATOM   5292  O OD2 . ASP B 1 234 ? -18.638 -38.059 10.243  1.00 88.16  ? 234 ASP B OD2 1 
ATOM   5293  N N   . HIS B 1 235 ? -18.550 -41.206 12.603  1.00 62.77  ? 235 HIS B N   1 
ATOM   5294  C CA  . HIS B 1 235 ? -19.103 -42.487 12.191  1.00 59.56  ? 235 HIS B CA  1 
ATOM   5295  C C   . HIS B 1 235 ? -20.392 -42.228 11.419  1.00 56.10  ? 235 HIS B C   1 
ATOM   5296  O O   . HIS B 1 235 ? -21.469 -42.666 11.822  1.00 60.88  ? 235 HIS B O   1 
ATOM   5297  C CB  . HIS B 1 235 ? -19.330 -43.409 13.393  1.00 60.45  ? 235 HIS B CB  1 
ATOM   5298  C CG  . HIS B 1 235 ? -18.992 -44.846 13.134  1.00 60.67  ? 235 HIS B CG  1 
ATOM   5299  N ND1 . HIS B 1 235 ? -19.880 -45.887 13.252  1.00 63.39  ? 235 HIS B ND1 1 
ATOM   5300  C CD2 . HIS B 1 235 ? -17.791 -45.381 12.777  1.00 63.43  ? 235 HIS B CD2 1 
ATOM   5301  C CE1 . HIS B 1 235 ? -19.245 -47.024 12.982  1.00 69.30  ? 235 HIS B CE1 1 
ATOM   5302  N NE2 . HIS B 1 235 ? -17.944 -46.732 12.674  1.00 65.16  ? 235 HIS B NE2 1 
ATOM   5303  N N   . GLU B 1 236 ? -20.212 -41.538 10.290  1.00 55.19  ? 236 GLU B N   1 
ATOM   5304  C CA  . GLU B 1 236 ? -21.246 -40.925 9.471   1.00 66.18  ? 236 GLU B CA  1 
ATOM   5305  C C   . GLU B 1 236 ? -22.297 -40.236 10.343  1.00 62.28  ? 236 GLU B C   1 
ATOM   5306  O O   . GLU B 1 236 ? -22.139 -40.186 11.561  1.00 62.37  ? 236 GLU B O   1 
ATOM   5307  C CB  . GLU B 1 236 ? -21.775 -41.908 8.412   1.00 80.21  ? 236 GLU B CB  1 
ATOM   5308  C CG  . GLU B 1 236 ? -22.401 -43.191 8.918   1.00 86.80  ? 236 GLU B CG  1 
ATOM   5309  C CD  . GLU B 1 236 ? -23.197 -43.920 7.841   1.00 98.19  ? 236 GLU B CD  1 
ATOM   5310  O OE1 . GLU B 1 236 ? -22.597 -44.272 6.775   1.00 94.91  ? 236 GLU B OE1 1 
ATOM   5311  O OE2 . GLU B 1 236 ? -24.427 -44.126 8.054   1.00 98.75  ? 236 GLU B OE2 1 
ATOM   5312  N N   . SER B 1 237 ? -23.330 -39.661 9.688   1.00 59.04  ? 237 SER B N   1 
ATOM   5313  C CA  . SER B 1 237 ? -24.289 -38.763 10.326  1.00 58.40  ? 237 SER B CA  1 
ATOM   5314  C C   . SER B 1 237 ? -25.578 -39.465 10.784  1.00 54.81  ? 237 SER B C   1 
ATOM   5315  O O   . SER B 1 237 ? -26.564 -38.802 11.110  1.00 51.01  ? 237 SER B O   1 
ATOM   5316  C CB  . SER B 1 237 ? -24.607 -37.586 9.413   1.00 59.49  ? 237 SER B CB  1 
ATOM   5317  O OG  . SER B 1 237 ? -25.357 -37.961 8.263   1.00 57.15  ? 237 SER B OG  1 
ATOM   5318  N N   . GLY B 1 238 ? -25.578 -40.800 10.861  1.00 54.77  ? 238 GLY B N   1 
ATOM   5319  C CA  . GLY B 1 238 ? -26.794 -41.528 11.188  1.00 54.22  ? 238 GLY B CA  1 
ATOM   5320  C C   . GLY B 1 238 ? -26.876 -41.902 12.670  1.00 52.43  ? 238 GLY B C   1 
ATOM   5321  O O   . GLY B 1 238 ? -27.971 -42.165 13.193  1.00 42.11  ? 238 GLY B O   1 
ATOM   5322  N N   . ASN B 1 239 ? -25.710 -41.916 13.339  1.00 48.72  ? 239 ASN B N   1 
ATOM   5323  C CA  . ASN B 1 239 ? -25.662 -42.221 14.756  1.00 45.27  ? 239 ASN B CA  1 
ATOM   5324  C C   . ASN B 1 239 ? -26.391 -41.117 15.529  1.00 45.60  ? 239 ASN B C   1 
ATOM   5325  O O   . ASN B 1 239 ? -26.514 -39.980 15.056  1.00 44.02  ? 239 ASN B O   1 
ATOM   5326  C CB  . ASN B 1 239 ? -24.214 -42.472 15.185  1.00 49.46  ? 239 ASN B CB  1 
ATOM   5327  C CG  . ASN B 1 239 ? -23.345 -41.235 15.143  1.00 48.45  ? 239 ASN B CG  1 
ATOM   5328  O OD1 . ASN B 1 239 ? -23.409 -40.406 16.053  1.00 44.03  ? 239 ASN B OD1 1 
ATOM   5329  N ND2 . ASN B 1 239 ? -22.523 -41.129 14.107  1.00 47.04  ? 239 ASN B ND2 1 
ATOM   5330  N N   . VAL B 1 240 ? -26.881 -41.465 16.725  1.00 43.95  ? 240 VAL B N   1 
ATOM   5331  C CA  . VAL B 1 240 ? -27.803 -40.607 17.449  1.00 47.48  ? 240 VAL B CA  1 
ATOM   5332  C C   . VAL B 1 240 ? -27.175 -39.245 17.709  1.00 44.95  ? 240 VAL B C   1 
ATOM   5333  O O   . VAL B 1 240 ? -27.857 -38.249 17.490  1.00 47.96  ? 240 VAL B O   1 
ATOM   5334  C CB  . VAL B 1 240 ? -28.284 -41.242 18.773  1.00 49.96  ? 240 VAL B CB  1 
ATOM   5335  C CG1 . VAL B 1 240 ? -28.943 -40.233 19.710  1.00 44.91  ? 240 VAL B CG1 1 
ATOM   5336  C CG2 . VAL B 1 240 ? -29.227 -42.404 18.522  1.00 49.79  ? 240 VAL B CG2 1 
ATOM   5337  N N   . SER B 1 241 ? -25.909 -39.215 18.181  1.00 47.46  ? 241 SER B N   1 
ATOM   5338  C CA  . SER B 1 241 ? -25.250 -37.959 18.552  1.00 45.60  ? 241 SER B CA  1 
ATOM   5339  C C   . SER B 1 241 ? -25.045 -37.071 17.312  1.00 46.63  ? 241 SER B C   1 
ATOM   5340  O O   . SER B 1 241 ? -25.476 -35.922 17.301  1.00 49.41  ? 241 SER B O   1 
ATOM   5341  C CB  . SER B 1 241 ? -23.969 -38.168 19.376  1.00 48.60  ? 241 SER B CB  1 
ATOM   5342  O OG  . SER B 1 241 ? -22.947 -38.905 18.690  1.00 44.16  ? 241 SER B OG  1 
ATOM   5343  N N   . ALA B 1 242 ? -24.457 -37.606 16.234  1.00 50.28  ? 242 ALA B N   1 
ATOM   5344  C CA  . ALA B 1 242 ? -24.254 -36.831 15.013  1.00 41.80  ? 242 ALA B CA  1 
ATOM   5345  C C   . ALA B 1 242 ? -25.588 -36.407 14.407  1.00 42.03  ? 242 ALA B C   1 
ATOM   5346  O O   . ALA B 1 242 ? -25.738 -35.258 14.016  1.00 45.11  ? 242 ALA B O   1 
ATOM   5347  C CB  . ALA B 1 242 ? -23.444 -37.633 14.035  1.00 42.57  ? 242 ALA B CB  1 
ATOM   5348  N N   . HIS B 1 243 ? -26.555 -37.339 14.345  1.00 43.34  ? 243 HIS B N   1 
ATOM   5349  C CA  . HIS B 1 243 ? -27.875 -37.093 13.774  1.00 38.49  ? 243 HIS B CA  1 
ATOM   5350  C C   . HIS B 1 243 ? -28.611 -36.026 14.570  1.00 40.19  ? 243 HIS B C   1 
ATOM   5351  O O   . HIS B 1 243 ? -29.344 -35.237 13.985  1.00 39.88  ? 243 HIS B O   1 
ATOM   5352  C CB  . HIS B 1 243 ? -28.702 -38.384 13.780  1.00 41.50  ? 243 HIS B CB  1 
ATOM   5353  C CG  . HIS B 1 243 ? -30.072 -38.328 13.159  1.00 41.90  ? 243 HIS B CG  1 
ATOM   5354  N ND1 . HIS B 1 243 ? -31.005 -39.352 13.282  1.00 42.38  ? 243 HIS B ND1 1 
ATOM   5355  C CD2 . HIS B 1 243 ? -30.644 -37.370 12.369  1.00 36.86  ? 243 HIS B CD2 1 
ATOM   5356  C CE1 . HIS B 1 243 ? -32.097 -39.025 12.570  1.00 38.82  ? 243 HIS B CE1 1 
ATOM   5357  N NE2 . HIS B 1 243 ? -31.889 -37.802 11.989  1.00 36.86  ? 243 HIS B NE2 1 
ATOM   5358  N N   . THR B 1 244 ? -28.455 -36.024 15.907  1.00 38.71  ? 244 THR B N   1 
ATOM   5359  C CA  . THR B 1 244 ? -29.126 -35.025 16.728  1.00 42.18  ? 244 THR B CA  1 
ATOM   5360  C C   . THR B 1 244 ? -28.604 -33.613 16.419  1.00 38.36  ? 244 THR B C   1 
ATOM   5361  O O   . THR B 1 244 ? -29.366 -32.651 16.285  1.00 32.18  ? 244 THR B O   1 
ATOM   5362  C CB  . THR B 1 244 ? -28.983 -35.344 18.221  1.00 45.54  ? 244 THR B CB  1 
ATOM   5363  O OG1 . THR B 1 244 ? -29.582 -36.611 18.507  1.00 45.08  ? 244 THR B OG1 1 
ATOM   5364  C CG2 . THR B 1 244 ? -29.631 -34.294 19.093  1.00 46.63  ? 244 THR B CG2 1 
ATOM   5365  N N   . ALA B 1 245 ? -27.282 -33.476 16.341  1.00 37.45  ? 245 ALA B N   1 
ATOM   5366  C CA  . ALA B 1 245 ? -26.680 -32.181 16.073  1.00 41.29  ? 245 ALA B CA  1 
ATOM   5367  C C   . ALA B 1 245 ? -27.147 -31.708 14.702  1.00 40.87  ? 245 ALA B C   1 
ATOM   5368  O O   . ALA B 1 245 ? -27.661 -30.602 14.534  1.00 44.46  ? 245 ALA B O   1 
ATOM   5369  C CB  . ALA B 1 245 ? -25.176 -32.264 16.177  1.00 41.31  ? 245 ALA B CB  1 
ATOM   5370  N N   . HIS B 1 246 ? -27.033 -32.601 13.731  1.00 40.82  ? 246 HIS B N   1 
ATOM   5371  C CA  . HIS B 1 246 ? -27.531 -32.310 12.402  1.00 41.69  ? 246 HIS B CA  1 
ATOM   5372  C C   . HIS B 1 246 ? -28.953 -31.762 12.489  1.00 37.36  ? 246 HIS B C   1 
ATOM   5373  O O   . HIS B 1 246 ? -29.277 -30.726 11.909  1.00 35.15  ? 246 HIS B O   1 
ATOM   5374  C CB  . HIS B 1 246 ? -27.411 -33.568 11.520  1.00 47.13  ? 246 HIS B CB  1 
ATOM   5375  C CG  . HIS B 1 246 ? -28.023 -33.401 10.165  1.00 53.78  ? 246 HIS B CG  1 
ATOM   5376  N ND1 . HIS B 1 246 ? -27.498 -32.607 9.170   1.00 59.71  ? 246 HIS B ND1 1 
ATOM   5377  C CD2 . HIS B 1 246 ? -29.191 -33.906 9.704   1.00 50.62  ? 246 HIS B CD2 1 
ATOM   5378  C CE1 . HIS B 1 246 ? -28.311 -32.619 8.120   1.00 54.17  ? 246 HIS B CE1 1 
ATOM   5379  N NE2 . HIS B 1 246 ? -29.365 -33.427 8.435   1.00 62.22  ? 246 HIS B NE2 1 
ATOM   5380  N N   . LEU B 1 247 ? -29.802 -32.470 13.234  1.00 40.76  ? 247 LEU B N   1 
ATOM   5381  C CA  . LEU B 1 247 ? -31.230 -32.204 13.237  1.00 44.48  ? 247 LEU B CA  1 
ATOM   5382  C C   . LEU B 1 247 ? -31.469 -30.854 13.894  1.00 41.33  ? 247 LEU B C   1 
ATOM   5383  O O   . LEU B 1 247 ? -32.113 -29.992 13.306  1.00 44.41  ? 247 LEU B O   1 
ATOM   5384  C CB  . LEU B 1 247 ? -31.934 -33.370 13.950  1.00 51.47  ? 247 LEU B CB  1 
ATOM   5385  C CG  . LEU B 1 247 ? -33.346 -33.143 14.501  1.00 51.51  ? 247 LEU B CG  1 
ATOM   5386  C CD1 . LEU B 1 247 ? -34.289 -32.552 13.465  1.00 48.44  ? 247 LEU B CD1 1 
ATOM   5387  C CD2 . LEU B 1 247 ? -33.912 -34.453 15.021  1.00 53.59  ? 247 LEU B CD2 1 
ATOM   5388  N N   . VAL B 1 248 ? -30.906 -30.650 15.086  1.00 40.87  ? 248 VAL B N   1 
ATOM   5389  C CA  . VAL B 1 248 ? -31.073 -29.381 15.784  1.00 42.47  ? 248 VAL B CA  1 
ATOM   5390  C C   . VAL B 1 248 ? -30.556 -28.224 14.928  1.00 39.54  ? 248 VAL B C   1 
ATOM   5391  O O   . VAL B 1 248 ? -31.207 -27.177 14.805  1.00 42.44  ? 248 VAL B O   1 
ATOM   5392  C CB  . VAL B 1 248 ? -30.396 -29.437 17.159  1.00 42.56  ? 248 VAL B CB  1 
ATOM   5393  C CG1 . VAL B 1 248 ? -30.245 -28.058 17.793  1.00 45.18  ? 248 VAL B CG1 1 
ATOM   5394  C CG2 . VAL B 1 248 ? -31.172 -30.371 18.081  1.00 42.07  ? 248 VAL B CG2 1 
ATOM   5395  N N   . ALA B 1 249 ? -29.385 -28.425 14.323  1.00 38.80  ? 249 ALA B N   1 
ATOM   5396  C CA  . ALA B 1 249 ? -28.744 -27.356 13.566  1.00 40.66  ? 249 ALA B CA  1 
ATOM   5397  C C   . ALA B 1 249 ? -29.549 -26.992 12.315  1.00 39.63  ? 249 ALA B C   1 
ATOM   5398  O O   . ALA B 1 249 ? -29.485 -25.871 11.817  1.00 40.24  ? 249 ALA B O   1 
ATOM   5399  C CB  . ALA B 1 249 ? -27.320 -27.756 13.243  1.00 41.92  ? 249 ALA B CB  1 
ATOM   5400  N N   . SER B 1 250 ? -30.334 -27.942 11.803  1.00 39.50  ? 250 SER B N   1 
ATOM   5401  C CA  . SER B 1 250 ? -31.113 -27.716 10.594  1.00 38.72  ? 250 SER B CA  1 
ATOM   5402  C C   . SER B 1 250 ? -32.227 -26.684 10.815  1.00 39.69  ? 250 SER B C   1 
ATOM   5403  O O   . SER B 1 250 ? -32.746 -26.121 9.846   1.00 36.95  ? 250 SER B O   1 
ATOM   5404  C CB  . SER B 1 250 ? -31.646 -29.022 10.085  1.00 38.69  ? 250 SER B CB  1 
ATOM   5405  O OG  . SER B 1 250 ? -32.715 -29.462 10.910  1.00 40.25  ? 250 SER B OG  1 
ATOM   5406  N N   . ALA B 1 251 ? -32.582 -26.402 12.084  1.00 43.45  ? 251 ALA B N   1 
ATOM   5407  C CA  . ALA B 1 251 ? -33.501 -25.315 12.435  1.00 40.29  ? 251 ALA B CA  1 
ATOM   5408  C C   . ALA B 1 251 ? -32.778 -23.957 12.550  1.00 47.33  ? 251 ALA B C   1 
ATOM   5409  O O   . ALA B 1 251 ? -33.410 -22.937 12.894  1.00 38.37  ? 251 ALA B O   1 
ATOM   5410  C CB  . ALA B 1 251 ? -34.181 -25.650 13.741  1.00 37.60  ? 251 ALA B CB  1 
ATOM   5411  N N   . LEU B 1 252 ? -31.451 -23.981 12.282  1.00 46.94  ? 252 LEU B N   1 
ATOM   5412  C CA  . LEU B 1 252 ? -30.518 -22.860 12.371  1.00 46.89  ? 252 LEU B CA  1 
ATOM   5413  C C   . LEU B 1 252 ? -30.200 -22.527 13.826  1.00 46.19  ? 252 LEU B C   1 
ATOM   5414  O O   . LEU B 1 252 ? -29.880 -21.380 14.137  1.00 46.76  ? 252 LEU B O   1 
ATOM   5415  C CB  . LEU B 1 252 ? -31.059 -21.630 11.636  1.00 42.14  ? 252 LEU B CB  1 
ATOM   5416  C CG  . LEU B 1 252 ? -31.252 -21.787 10.131  1.00 41.63  ? 252 LEU B CG  1 
ATOM   5417  C CD1 . LEU B 1 252 ? -31.781 -20.481 9.574   1.00 42.75  ? 252 LEU B CD1 1 
ATOM   5418  C CD2 . LEU B 1 252 ? -29.955 -22.217 9.427   1.00 42.11  ? 252 LEU B CD2 1 
ATOM   5419  N N   . SER B 1 253 ? -30.281 -23.532 14.703  1.00 42.80  ? 253 SER B N   1 
ATOM   5420  C CA  . SER B 1 253 ? -29.681 -23.421 16.016  1.00 45.84  ? 253 SER B CA  1 
ATOM   5421  C C   . SER B 1 253 ? -28.172 -23.438 15.813  1.00 41.34  ? 253 SER B C   1 
ATOM   5422  O O   . SER B 1 253 ? -27.677 -24.155 14.955  1.00 48.72  ? 253 SER B O   1 
ATOM   5423  C CB  . SER B 1 253 ? -30.170 -24.532 16.963  1.00 44.44  ? 253 SER B CB  1 
ATOM   5424  O OG  . SER B 1 253 ? -31.513 -24.278 17.384  1.00 43.03  ? 253 SER B OG  1 
ATOM   5425  N N   . ASP B 1 254 ? -27.443 -22.653 16.595  1.00 36.12  ? 254 ASP B N   1 
ATOM   5426  C CA  . ASP B 1 254 ? -25.983 -22.650 16.515  1.00 36.89  ? 254 ASP B CA  1 
ATOM   5427  C C   . ASP B 1 254 ? -25.382 -23.963 17.033  1.00 36.14  ? 254 ASP B C   1 
ATOM   5428  O O   . ASP B 1 254 ? -26.065 -24.830 17.583  1.00 38.54  ? 254 ASP B O   1 
ATOM   5429  C CB  . ASP B 1 254 ? -25.442 -21.441 17.274  1.00 37.76  ? 254 ASP B CB  1 
ATOM   5430  C CG  . ASP B 1 254 ? -25.978 -21.406 18.696  1.00 44.07  ? 254 ASP B CG  1 
ATOM   5431  O OD1 . ASP B 1 254 ? -25.612 -22.353 19.472  1.00 47.40  ? 254 ASP B OD1 1 
ATOM   5432  O OD2 . ASP B 1 254 ? -26.807 -20.464 19.011  1.00 44.41  ? 254 ASP B OD2 1 
ATOM   5433  N N   . ALA B 1 255 ? -24.058 -24.073 16.903  1.00 38.47  ? 255 ALA B N   1 
ATOM   5434  C CA  . ALA B 1 255 ? -23.320 -25.286 17.226  1.00 39.44  ? 255 ALA B CA  1 
ATOM   5435  C C   . ALA B 1 255 ? -23.319 -25.580 18.720  1.00 35.46  ? 255 ALA B C   1 
ATOM   5436  O O   . ALA B 1 255 ? -23.080 -26.719 19.120  1.00 37.37  ? 255 ALA B O   1 
ATOM   5437  C CB  . ALA B 1 255 ? -21.897 -25.143 16.741  1.00 40.91  ? 255 ALA B CB  1 
ATOM   5438  N N   . TYR B 1 256 ? -23.497 -24.544 19.534  1.00 34.13  ? 256 TYR B N   1 
ATOM   5439  C CA  . TYR B 1 256 ? -23.545 -24.736 20.977  1.00 34.85  ? 256 TYR B CA  1 
ATOM   5440  C C   . TYR B 1 256 ? -24.817 -25.492 21.360  1.00 34.13  ? 256 TYR B C   1 
ATOM   5441  O O   . TYR B 1 256 ? -24.761 -26.487 22.067  1.00 36.46  ? 256 TYR B O   1 
ATOM   5442  C CB  . TYR B 1 256 ? -23.417 -23.367 21.623  1.00 35.83  ? 256 TYR B CB  1 
ATOM   5443  C CG  . TYR B 1 256 ? -22.053 -22.752 21.456  1.00 36.98  ? 256 TYR B CG  1 
ATOM   5444  C CD1 . TYR B 1 256 ? -21.004 -23.197 22.230  1.00 39.04  ? 256 TYR B CD1 1 
ATOM   5445  C CD2 . TYR B 1 256 ? -21.795 -21.759 20.530  1.00 37.34  ? 256 TYR B CD2 1 
ATOM   5446  C CE1 . TYR B 1 256 ? -19.741 -22.643 22.126  1.00 43.40  ? 256 TYR B CE1 1 
ATOM   5447  C CE2 . TYR B 1 256 ? -20.538 -21.187 20.422  1.00 41.12  ? 256 TYR B CE2 1 
ATOM   5448  C CZ  . TYR B 1 256 ? -19.501 -21.617 21.234  1.00 41.39  ? 256 TYR B CZ  1 
ATOM   5449  O OH  . TYR B 1 256 ? -18.206 -21.115 21.214  1.00 41.39  ? 256 TYR B OH  1 
ATOM   5450  N N   . TYR B 1 257 ? -25.960 -25.057 20.815  1.00 35.40  ? 257 TYR B N   1 
ATOM   5451  C CA  . TYR B 1 257 ? -27.228 -25.753 20.983  1.00 32.48  ? 257 TYR B CA  1 
ATOM   5452  C C   . TYR B 1 257 ? -27.150 -27.158 20.391  1.00 31.87  ? 257 TYR B C   1 
ATOM   5453  O O   . TYR B 1 257 ? -27.515 -28.153 21.023  1.00 33.74  ? 257 TYR B O   1 
ATOM   5454  C CB  . TYR B 1 257 ? -28.334 -24.933 20.315  1.00 32.62  ? 257 TYR B CB  1 
ATOM   5455  C CG  . TYR B 1 257 ? -28.918 -23.753 21.075  1.00 30.56  ? 257 TYR B CG  1 
ATOM   5456  C CD1 . TYR B 1 257 ? -29.305 -23.843 22.406  1.00 33.62  ? 257 TYR B CD1 1 
ATOM   5457  C CD2 . TYR B 1 257 ? -29.233 -22.579 20.417  1.00 30.30  ? 257 TYR B CD2 1 
ATOM   5458  C CE1 . TYR B 1 257 ? -29.942 -22.799 23.069  1.00 33.22  ? 257 TYR B CE1 1 
ATOM   5459  C CE2 . TYR B 1 257 ? -29.836 -21.513 21.061  1.00 28.10  ? 257 TYR B CE2 1 
ATOM   5460  C CZ  . TYR B 1 257 ? -30.207 -21.621 22.393  1.00 34.53  ? 257 TYR B CZ  1 
ATOM   5461  O OH  . TYR B 1 257 ? -30.841 -20.553 23.058  1.00 39.44  ? 257 TYR B OH  1 
ATOM   5462  N N   . ALA B 1 258 ? -26.640 -27.246 19.162  1.00 35.95  ? 258 ALA B N   1 
ATOM   5463  C CA  . ALA B 1 258 ? -26.577 -28.514 18.439  1.00 32.81  ? 258 ALA B CA  1 
ATOM   5464  C C   . ALA B 1 258 ? -25.714 -29.556 19.141  1.00 31.26  ? 258 ALA B C   1 
ATOM   5465  O O   . ALA B 1 258 ? -26.062 -30.749 19.179  1.00 30.08  ? 258 ALA B O   1 
ATOM   5466  C CB  . ALA B 1 258 ? -26.020 -28.283 17.074  1.00 33.85  ? 258 ALA B CB  1 
ATOM   5467  N N   . TYR B 1 259 ? -24.538 -29.124 19.603  1.00 31.18  ? 259 TYR B N   1 
ATOM   5468  C CA  . TYR B 1 259 ? -23.598 -30.056 20.207  1.00 31.22  ? 259 TYR B CA  1 
ATOM   5469  C C   . TYR B 1 259 ? -24.011 -30.373 21.649  1.00 31.34  ? 259 TYR B C   1 
ATOM   5470  O O   . TYR B 1 259 ? -23.816 -31.485 22.131  1.00 34.70  ? 259 TYR B O   1 
ATOM   5471  C CB  . TYR B 1 259 ? -22.147 -29.572 20.085  1.00 32.23  ? 259 TYR B CB  1 
ATOM   5472  C CG  . TYR B 1 259 ? -21.222 -30.755 20.159  1.00 33.96  ? 259 TYR B CG  1 
ATOM   5473  C CD1 . TYR B 1 259 ? -21.342 -31.766 19.220  1.00 36.94  ? 259 TYR B CD1 1 
ATOM   5474  C CD2 . TYR B 1 259 ? -20.368 -30.963 21.232  1.00 37.10  ? 259 TYR B CD2 1 
ATOM   5475  C CE1 . TYR B 1 259 ? -20.608 -32.937 19.297  1.00 37.67  ? 259 TYR B CE1 1 
ATOM   5476  C CE2 . TYR B 1 259 ? -19.601 -32.118 21.319  1.00 38.91  ? 259 TYR B CE2 1 
ATOM   5477  C CZ  . TYR B 1 259 ? -19.724 -33.107 20.344  1.00 42.06  ? 259 TYR B CZ  1 
ATOM   5478  O OH  . TYR B 1 259 ? -18.988 -34.281 20.330  1.00 48.79  ? 259 TYR B OH  1 
ATOM   5479  N N   . SER B 1 260 ? -24.605 -29.412 22.358  1.00 35.11  ? 260 SER B N   1 
ATOM   5480  C CA  . SER B 1 260 ? -25.215 -29.709 23.647  1.00 32.66  ? 260 SER B CA  1 
ATOM   5481  C C   . SER B 1 260 ? -26.271 -30.805 23.496  1.00 32.78  ? 260 SER B C   1 
ATOM   5482  O O   . SER B 1 260 ? -26.243 -31.771 24.245  1.00 32.95  ? 260 SER B O   1 
ATOM   5483  C CB  . SER B 1 260 ? -25.800 -28.472 24.258  1.00 33.99  ? 260 SER B CB  1 
ATOM   5484  O OG  . SER B 1 260 ? -26.520 -28.787 25.441  1.00 41.58  ? 260 SER B OG  1 
ATOM   5485  N N   . ALA B 1 261 ? -27.200 -30.641 22.533  1.00 30.48  ? 261 ALA B N   1 
ATOM   5486  C CA  . ALA B 1 261 ? -28.211 -31.645 22.236  1.00 28.63  ? 261 ALA B CA  1 
ATOM   5487  C C   . ALA B 1 261 ? -27.613 -33.012 21.915  1.00 30.14  ? 261 ALA B C   1 
ATOM   5488  O O   . ALA B 1 261 ? -28.128 -34.036 22.345  1.00 41.01  ? 261 ALA B O   1 
ATOM   5489  C CB  . ALA B 1 261 ? -29.048 -31.170 21.065  1.00 30.52  ? 261 ALA B CB  1 
ATOM   5490  N N   . ALA B 1 262 ? -26.562 -33.038 21.099  1.00 30.81  ? 262 ALA B N   1 
ATOM   5491  C CA  . ALA B 1 262 ? -25.888 -34.267 20.715  1.00 29.78  ? 262 ALA B CA  1 
ATOM   5492  C C   . ALA B 1 262 ? -25.333 -35.019 21.918  1.00 29.11  ? 262 ALA B C   1 
ATOM   5493  O O   . ALA B 1 262 ? -25.410 -36.239 21.948  1.00 37.79  ? 262 ALA B O   1 
ATOM   5494  C CB  . ALA B 1 262 ? -24.781 -33.921 19.740  1.00 33.54  ? 262 ALA B CB  1 
ATOM   5495  N N   . MET B 1 263 ? -24.768 -34.298 22.889  1.00 29.95  ? 263 MET B N   1 
ATOM   5496  C CA  . MET B 1 263 ? -24.238 -34.892 24.119  1.00 32.44  ? 263 MET B CA  1 
ATOM   5497  C C   . MET B 1 263 ? -25.368 -35.459 24.991  1.00 33.31  ? 263 MET B C   1 
ATOM   5498  O O   . MET B 1 263 ? -25.193 -36.461 25.679  1.00 34.39  ? 263 MET B O   1 
ATOM   5499  C CB  . MET B 1 263 ? -23.422 -33.871 24.937  1.00 31.39  ? 263 MET B CB  1 
ATOM   5500  C CG  . MET B 1 263 ? -22.164 -33.402 24.232  1.00 34.39  ? 263 MET B CG  1 
ATOM   5501  S SD  . MET B 1 263 ? -21.069 -34.746 23.681  1.00 36.99  ? 263 MET B SD  1 
ATOM   5502  C CE  . MET B 1 263 ? -21.776 -35.180 22.090  1.00 36.72  ? 263 MET B CE  1 
ATOM   5503  N N   . CYS B 1 264 ? -26.545 -34.830 24.964  1.00 34.19  ? 264 CYS B N   1 
ATOM   5504  C CA  . CYS B 1 264 ? -27.731 -35.449 25.549  1.00 42.59  ? 264 CYS B CA  1 
ATOM   5505  C C   . CYS B 1 264 ? -28.012 -36.822 24.914  1.00 39.05  ? 264 CYS B C   1 
ATOM   5506  O O   . CYS B 1 264 ? -28.366 -37.756 25.620  1.00 39.54  ? 264 CYS B O   1 
ATOM   5507  C CB  . CYS B 1 264 ? -28.949 -34.536 25.424  1.00 42.61  ? 264 CYS B CB  1 
ATOM   5508  S SG  . CYS B 1 264 ? -28.734 -32.976 26.317  1.00 42.41  ? 264 CYS B SG  1 
ATOM   5509  N N   . GLY B 1 265 ? -27.821 -36.946 23.588  1.00 41.31  ? 265 GLY B N   1 
ATOM   5510  C CA  . GLY B 1 265 ? -27.939 -38.214 22.874  1.00 37.18  ? 265 GLY B CA  1 
ATOM   5511  C C   . GLY B 1 265 ? -26.824 -39.205 23.229  1.00 41.87  ? 265 GLY B C   1 
ATOM   5512  O O   . GLY B 1 265 ? -27.075 -40.394 23.468  1.00 40.48  ? 265 GLY B O   1 
ATOM   5513  N N   . LEU B 1 266 ? -25.579 -38.712 23.242  1.00 39.64  ? 266 LEU B N   1 
ATOM   5514  C CA  . LEU B 1 266 ? -24.441 -39.562 23.532  1.00 38.69  ? 266 LEU B CA  1 
ATOM   5515  C C   . LEU B 1 266 ? -24.494 -40.127 24.956  1.00 37.27  ? 266 LEU B C   1 
ATOM   5516  O O   . LEU B 1 266 ? -23.921 -41.172 25.223  1.00 37.71  ? 266 LEU B O   1 
ATOM   5517  C CB  . LEU B 1 266 ? -23.164 -38.750 23.324  1.00 42.20  ? 266 LEU B CB  1 
ATOM   5518  C CG  . LEU B 1 266 ? -21.873 -39.560 23.422  1.00 43.27  ? 266 LEU B CG  1 
ATOM   5519  C CD1 . LEU B 1 266 ? -21.827 -40.596 22.312  1.00 42.84  ? 266 LEU B CD1 1 
ATOM   5520  C CD2 . LEU B 1 266 ? -20.649 -38.654 23.373  1.00 43.93  ? 266 LEU B CD2 1 
ATOM   5521  N N   . ALA B 1 267 ? -25.184 -39.461 25.879  1.00 38.25  ? 267 ALA B N   1 
ATOM   5522  C CA  . ALA B 1 267 ? -25.260 -39.927 27.262  1.00 42.29  ? 267 ALA B CA  1 
ATOM   5523  C C   . ALA B 1 267 ? -26.186 -41.142 27.408  1.00 43.38  ? 267 ALA B C   1 
ATOM   5524  O O   . ALA B 1 267 ? -26.186 -41.793 28.453  1.00 38.51  ? 267 ALA B O   1 
ATOM   5525  C CB  . ALA B 1 267 ? -25.714 -38.791 28.158  1.00 43.43  ? 267 ALA B CB  1 
ATOM   5526  N N   . GLY B 1 268 ? -26.995 -41.423 26.370  1.00 48.61  ? 268 GLY B N   1 
ATOM   5527  C CA  . GLY B 1 268 ? -27.846 -42.606 26.325  1.00 44.63  ? 268 GLY B CA  1 
ATOM   5528  C C   . GLY B 1 268 ? -27.077 -43.909 26.547  1.00 44.32  ? 268 GLY B C   1 
ATOM   5529  O O   . GLY B 1 268 ? -26.003 -44.120 25.995  1.00 42.17  ? 268 GLY B O   1 
ATOM   5530  N N   . PRO B 1 269 ? -27.601 -44.853 27.357  1.00 45.13  ? 269 PRO B N   1 
ATOM   5531  C CA  . PRO B 1 269 ? -26.937 -46.143 27.555  1.00 41.09  ? 269 PRO B CA  1 
ATOM   5532  C C   . PRO B 1 269 ? -26.745 -46.953 26.279  1.00 41.07  ? 269 PRO B C   1 
ATOM   5533  O O   . PRO B 1 269 ? -25.782 -47.713 26.180  1.00 49.65  ? 269 PRO B O   1 
ATOM   5534  C CB  . PRO B 1 269 ? -27.885 -46.897 28.493  1.00 43.77  ? 269 PRO B CB  1 
ATOM   5535  C CG  . PRO B 1 269 ? -28.680 -45.807 29.193  1.00 45.03  ? 269 PRO B CG  1 
ATOM   5536  C CD  . PRO B 1 269 ? -28.834 -44.724 28.152  1.00 44.57  ? 269 PRO B CD  1 
ATOM   5537  N N   . LEU B 1 270 ? -27.643 -46.777 25.299  1.00 42.77  ? 270 LEU B N   1 
ATOM   5538  C CA  . LEU B 1 270 ? -27.514 -47.478 24.025  1.00 42.40  ? 270 LEU B CA  1 
ATOM   5539  C C   . LEU B 1 270 ? -26.549 -46.772 23.076  1.00 43.75  ? 270 LEU B C   1 
ATOM   5540  O O   . LEU B 1 270 ? -26.415 -47.188 21.935  1.00 49.15  ? 270 LEU B O   1 
ATOM   5541  C CB  . LEU B 1 270 ? -28.878 -47.594 23.345  1.00 39.75  ? 270 LEU B CB  1 
ATOM   5542  C CG  . LEU B 1 270 ? -29.932 -48.396 24.096  1.00 38.83  ? 270 LEU B CG  1 
ATOM   5543  C CD1 . LEU B 1 270 ? -31.110 -48.667 23.172  1.00 38.73  ? 270 LEU B CD1 1 
ATOM   5544  C CD2 . LEU B 1 270 ? -29.352 -49.689 24.622  1.00 36.56  ? 270 LEU B CD2 1 
ATOM   5545  N N   . HIS B 1 271 ? -25.876 -45.713 23.522  1.00 50.26  ? 271 HIS B N   1 
ATOM   5546  C CA  . HIS B 1 271 ? -24.938 -45.013 22.658  1.00 49.00  ? 271 HIS B CA  1 
ATOM   5547  C C   . HIS B 1 271 ? -23.583 -44.855 23.354  1.00 57.55  ? 271 HIS B C   1 
ATOM   5548  O O   . HIS B 1 271 ? -22.600 -45.473 22.943  1.00 76.10  ? 271 HIS B O   1 
ATOM   5549  C CB  . HIS B 1 271 ? -25.558 -43.686 22.224  1.00 46.64  ? 271 HIS B CB  1 
ATOM   5550  C CG  . HIS B 1 271 ? -24.908 -43.074 21.028  1.00 49.95  ? 271 HIS B CG  1 
ATOM   5551  N ND1 . HIS B 1 271 ? -23.916 -43.693 20.305  1.00 54.50  ? 271 HIS B ND1 1 
ATOM   5552  C CD2 . HIS B 1 271 ? -25.131 -41.850 20.462  1.00 50.90  ? 271 HIS B CD2 1 
ATOM   5553  C CE1 . HIS B 1 271 ? -23.553 -42.889 19.305  1.00 54.48  ? 271 HIS B CE1 1 
ATOM   5554  N NE2 . HIS B 1 271 ? -24.285 -41.730 19.393  1.00 54.05  ? 271 HIS B NE2 1 
ATOM   5555  N N   . GLY B 1 272 ? -23.535 -44.083 24.448  1.00 57.77  ? 272 GLY B N   1 
ATOM   5556  C CA  . GLY B 1 272 ? -22.274 -43.608 24.991  1.00 52.76  ? 272 GLY B CA  1 
ATOM   5557  C C   . GLY B 1 272 ? -21.753 -44.414 26.175  1.00 54.78  ? 272 GLY B C   1 
ATOM   5558  O O   . GLY B 1 272 ? -20.640 -44.155 26.618  1.00 48.62  ? 272 GLY B O   1 
ATOM   5559  N N   . LEU B 1 273 ? -22.531 -45.393 26.667  1.00 69.98  ? 273 LEU B N   1 
ATOM   5560  C CA  . LEU B 1 273 ? -22.182 -46.084 27.905  1.00 72.18  ? 273 LEU B CA  1 
ATOM   5561  C C   . LEU B 1 273 ? -21.643 -47.486 27.629  1.00 72.02  ? 273 LEU B C   1 
ATOM   5562  O O   . LEU B 1 273 ? -21.356 -48.216 28.580  1.00 82.39  ? 273 LEU B O   1 
ATOM   5563  C CB  . LEU B 1 273 ? -23.405 -46.146 28.832  1.00 82.41  ? 273 LEU B CB  1 
ATOM   5564  C CG  . LEU B 1 273 ? -23.556 -44.996 29.837  1.00 86.15  ? 273 LEU B CG  1 
ATOM   5565  C CD1 . LEU B 1 273 ? -23.503 -43.620 29.155  1.00 83.96  ? 273 LEU B CD1 1 
ATOM   5566  C CD2 . LEU B 1 273 ? -24.848 -45.165 30.635  1.00 82.25  ? 273 LEU B CD2 1 
ATOM   5567  N N   . ALA B 1 274 ? -21.451 -47.838 26.351  1.00 70.85  ? 274 ALA B N   1 
ATOM   5568  C CA  . ALA B 1 274 ? -21.057 -49.189 25.976  1.00 69.76  ? 274 ALA B CA  1 
ATOM   5569  C C   . ALA B 1 274 ? -19.647 -49.530 26.474  1.00 73.83  ? 274 ALA B C   1 
ATOM   5570  O O   . ALA B 1 274 ? -19.363 -50.684 26.799  1.00 72.24  ? 274 ALA B O   1 
ATOM   5571  C CB  . ALA B 1 274 ? -21.179 -49.338 24.481  1.00 67.84  ? 274 ALA B CB  1 
ATOM   5572  N N   . ASN B 1 275 ? -18.787 -48.505 26.570  1.00 83.98  ? 275 ASN B N   1 
ATOM   5573  C CA  . ASN B 1 275 ? -17.358 -48.646 26.834  1.00 81.41  ? 275 ASN B CA  1 
ATOM   5574  C C   . ASN B 1 275 ? -17.091 -49.070 28.287  1.00 77.75  ? 275 ASN B C   1 
ATOM   5575  O O   . ASN B 1 275 ? -16.262 -49.953 28.522  1.00 64.58  ? 275 ASN B O   1 
ATOM   5576  C CB  . ASN B 1 275 ? -16.654 -47.335 26.452  1.00 82.84  ? 275 ASN B CB  1 
ATOM   5577  C CG  . ASN B 1 275 ? -15.143 -47.370 26.562  1.00 84.65  ? 275 ASN B CG  1 
ATOM   5578  O OD1 . ASN B 1 275 ? -14.573 -48.341 27.057  1.00 93.89  ? 275 ASN B OD1 1 
ATOM   5579  N ND2 . ASN B 1 275 ? -14.488 -46.300 26.129  1.00 79.90  ? 275 ASN B ND2 1 
ATOM   5580  N N   . GLN B 1 276 ? -17.767 -48.406 29.248  1.00 79.51  ? 276 GLN B N   1 
ATOM   5581  C CA  . GLN B 1 276 ? -17.664 -48.721 30.670  1.00 79.11  ? 276 GLN B CA  1 
ATOM   5582  C C   . GLN B 1 276 ? -18.353 -50.049 30.983  1.00 81.73  ? 276 GLN B C   1 
ATOM   5583  O O   . GLN B 1 276 ? -17.832 -50.840 31.773  1.00 64.50  ? 276 GLN B O   1 
ATOM   5584  C CB  . GLN B 1 276 ? -18.255 -47.649 31.599  1.00 80.03  ? 276 GLN B CB  1 
ATOM   5585  C CG  . GLN B 1 276 ? -19.521 -46.950 31.132  1.00 82.53  ? 276 GLN B CG  1 
ATOM   5586  C CD  . GLN B 1 276 ? -19.190 -45.714 30.318  1.00 87.82  ? 276 GLN B CD  1 
ATOM   5587  O OE1 . GLN B 1 276 ? -18.527 -45.781 29.276  1.00 84.45  ? 276 GLN B OE1 1 
ATOM   5588  N NE2 . GLN B 1 276 ? -19.632 -44.560 30.802  1.00 77.15  ? 276 GLN B NE2 1 
ATOM   5589  N N   . GLU B 1 277 ? -19.522 -50.280 30.362  1.00 92.87  ? 277 GLU B N   1 
ATOM   5590  C CA  . GLU B 1 277 ? -20.318 -51.476 30.616  1.00 88.39  ? 277 GLU B CA  1 
ATOM   5591  C C   . GLU B 1 277 ? -19.582 -52.725 30.116  1.00 77.18  ? 277 GLU B C   1 
ATOM   5592  O O   . GLU B 1 277 ? -19.824 -53.812 30.629  1.00 61.92  ? 277 GLU B O   1 
ATOM   5593  C CB  . GLU B 1 277 ? -21.730 -51.298 30.052  1.00 88.70  ? 277 GLU B CB  1 
ATOM   5594  C CG  . GLU B 1 277 ? -22.534 -50.259 30.843  1.00 98.95  ? 277 GLU B CG  1 
ATOM   5595  C CD  . GLU B 1 277 ? -24.011 -50.114 30.494  1.00 110.45 ? 277 GLU B CD  1 
ATOM   5596  O OE1 . GLU B 1 277 ? -24.508 -50.907 29.664  1.00 117.58 ? 277 GLU B OE1 1 
ATOM   5597  O OE2 . GLU B 1 277 ? -24.670 -49.203 31.051  1.00 102.04 ? 277 GLU B OE2 1 
ATOM   5598  N N   . VAL B 1 278 ? -18.640 -52.558 29.170  1.00 66.09  ? 278 VAL B N   1 
ATOM   5599  C CA  . VAL B 1 278 ? -17.761 -53.638 28.740  1.00 57.76  ? 278 VAL B CA  1 
ATOM   5600  C C   . VAL B 1 278 ? -16.723 -53.959 29.811  1.00 68.17  ? 278 VAL B C   1 
ATOM   5601  O O   . VAL B 1 278 ? -16.564 -55.123 30.184  1.00 72.60  ? 278 VAL B O   1 
ATOM   5602  C CB  . VAL B 1 278 ? -17.045 -53.307 27.419  1.00 49.78  ? 278 VAL B CB  1 
ATOM   5603  C CG1 . VAL B 1 278 ? -15.789 -54.155 27.215  1.00 43.89  ? 278 VAL B CG1 1 
ATOM   5604  C CG2 . VAL B 1 278 ? -17.991 -53.419 26.234  1.00 50.23  ? 278 VAL B CG2 1 
ATOM   5605  N N   . LEU B 1 279 ? -15.962 -52.932 30.223  1.00 71.88  ? 279 LEU B N   1 
ATOM   5606  C CA  . LEU B 1 279 ? -14.838 -53.104 31.129  1.00 71.03  ? 279 LEU B CA  1 
ATOM   5607  C C   . LEU B 1 279 ? -15.327 -53.660 32.471  1.00 77.16  ? 279 LEU B C   1 
ATOM   5608  O O   . LEU B 1 279 ? -14.737 -54.620 32.976  1.00 70.10  ? 279 LEU B O   1 
ATOM   5609  C CB  . LEU B 1 279 ? -14.128 -51.755 31.281  1.00 73.79  ? 279 LEU B CB  1 
ATOM   5610  C CG  . LEU B 1 279 ? -12.936 -51.721 32.241  1.00 77.09  ? 279 LEU B CG  1 
ATOM   5611  C CD1 . LEU B 1 279 ? -11.827 -52.649 31.774  1.00 78.07  ? 279 LEU B CD1 1 
ATOM   5612  C CD2 . LEU B 1 279 ? -12.405 -50.302 32.387  1.00 77.20  ? 279 LEU B CD2 1 
ATOM   5613  N N   . LYS B 1 280 ? -16.401 -53.058 33.029  1.00 75.12  ? 280 LYS B N   1 
ATOM   5614  C CA  . LYS B 1 280 ? -16.998 -53.499 34.288  1.00 75.42  ? 280 LYS B CA  1 
ATOM   5615  C C   . LYS B 1 280 ? -17.266 -55.002 34.261  1.00 71.00  ? 280 LYS B C   1 
ATOM   5616  O O   . LYS B 1 280 ? -16.964 -55.733 35.203  1.00 59.82  ? 280 LYS B O   1 
ATOM   5617  C CB  . LYS B 1 280 ? -18.326 -52.784 34.548  1.00 73.31  ? 280 LYS B CB  1 
ATOM   5618  C CG  . LYS B 1 280 ? -18.212 -51.375 35.103  1.00 73.51  ? 280 LYS B CG  1 
ATOM   5619  C CD  . LYS B 1 280 ? -19.562 -50.750 35.348  1.00 74.71  ? 280 LYS B CD  1 
ATOM   5620  C CE  . LYS B 1 280 ? -19.433 -49.323 35.828  1.00 82.46  ? 280 LYS B CE  1 
ATOM   5621  N NZ  . LYS B 1 280 ? -20.484 -48.978 36.807  1.00 81.54  ? 280 LYS B NZ  1 
ATOM   5622  N N   . TRP B 1 281 ? -17.853 -55.433 33.150  1.00 74.31  ? 281 TRP B N   1 
ATOM   5623  C CA  . TRP B 1 281 ? -18.220 -56.814 32.930  1.00 86.07  ? 281 TRP B CA  1 
ATOM   5624  C C   . TRP B 1 281 ? -16.966 -57.701 32.784  1.00 92.76  ? 281 TRP B C   1 
ATOM   5625  O O   . TRP B 1 281 ? -16.974 -58.846 33.241  1.00 98.42  ? 281 TRP B O   1 
ATOM   5626  C CB  . TRP B 1 281 ? -19.199 -56.855 31.743  1.00 89.19  ? 281 TRP B CB  1 
ATOM   5627  C CG  . TRP B 1 281 ? -19.580 -58.228 31.293  1.00 97.31  ? 281 TRP B CG  1 
ATOM   5628  C CD1 . TRP B 1 281 ? -20.709 -58.932 31.613  1.00 94.61  ? 281 TRP B CD1 1 
ATOM   5629  C CD2 . TRP B 1 281 ? -18.816 -59.056 30.397  1.00 100.68 ? 281 TRP B CD2 1 
ATOM   5630  N NE1 . TRP B 1 281 ? -20.668 -60.165 31.019  1.00 93.86  ? 281 TRP B NE1 1 
ATOM   5631  C CE2 . TRP B 1 281 ? -19.532 -60.263 30.251  1.00 97.13  ? 281 TRP B CE2 1 
ATOM   5632  C CE3 . TRP B 1 281 ? -17.597 -58.899 29.722  1.00 95.26  ? 281 TRP B CE3 1 
ATOM   5633  C CZ2 . TRP B 1 281 ? -19.051 -61.309 29.462  1.00 93.60  ? 281 TRP B CZ2 1 
ATOM   5634  C CZ3 . TRP B 1 281 ? -17.132 -59.930 28.934  1.00 92.96  ? 281 TRP B CZ3 1 
ATOM   5635  C CH2 . TRP B 1 281 ? -17.854 -61.116 28.805  1.00 93.84  ? 281 TRP B CH2 1 
ATOM   5636  N N   . ILE B 1 282 ? -15.869 -57.185 32.198  1.00 81.59  ? 282 ILE B N   1 
ATOM   5637  C CA  . ILE B 1 282 ? -14.620 -57.940 32.130  1.00 69.47  ? 282 ILE B CA  1 
ATOM   5638  C C   . ILE B 1 282 ? -14.032 -58.067 33.537  1.00 74.53  ? 282 ILE B C   1 
ATOM   5639  O O   . ILE B 1 282 ? -13.543 -59.129 33.904  1.00 75.35  ? 282 ILE B O   1 
ATOM   5640  C CB  . ILE B 1 282 ? -13.601 -57.320 31.143  1.00 63.95  ? 282 ILE B CB  1 
ATOM   5641  C CG1 . ILE B 1 282 ? -14.065 -57.460 29.688  1.00 60.86  ? 282 ILE B CG1 1 
ATOM   5642  C CG2 . ILE B 1 282 ? -12.196 -57.896 31.341  1.00 56.62  ? 282 ILE B CG2 1 
ATOM   5643  C CD1 . ILE B 1 282 ? -13.065 -56.951 28.668  1.00 60.65  ? 282 ILE B CD1 1 
ATOM   5644  N N   . GLN B 1 283 ? -14.077 -56.979 34.314  1.00 82.98  ? 283 GLN B N   1 
ATOM   5645  C CA  . GLN B 1 283 ? -13.518 -56.938 35.661  1.00 84.46  ? 283 GLN B CA  1 
ATOM   5646  C C   . GLN B 1 283 ? -14.312 -57.808 36.640  1.00 80.89  ? 283 GLN B C   1 
ATOM   5647  O O   . GLN B 1 283 ? -13.720 -58.422 37.531  1.00 74.88  ? 283 GLN B O   1 
ATOM   5648  C CB  . GLN B 1 283 ? -13.483 -55.491 36.160  1.00 89.57  ? 283 GLN B CB  1 
ATOM   5649  C CG  . GLN B 1 283 ? -12.493 -54.609 35.412  1.00 86.09  ? 283 GLN B CG  1 
ATOM   5650  C CD  . GLN B 1 283 ? -12.468 -53.211 35.975  1.00 83.52  ? 283 GLN B CD  1 
ATOM   5651  O OE1 . GLN B 1 283 ? -11.429 -52.705 36.392  1.00 94.88  ? 283 GLN B OE1 1 
ATOM   5652  N NE2 . GLN B 1 283 ? -13.627 -52.574 36.005  1.00 80.95  ? 283 GLN B NE2 1 
ATOM   5653  N N   . GLU B 1 284 ? -15.646 -57.812 36.497  1.00 90.16  ? 284 GLU B N   1 
ATOM   5654  C CA  . GLU B 1 284 ? -16.542 -58.674 37.262  1.00 96.75  ? 284 GLU B CA  1 
ATOM   5655  C C   . GLU B 1 284 ? -16.261 -60.153 36.957  1.00 99.54  ? 284 GLU B C   1 
ATOM   5656  O O   . GLU B 1 284 ? -16.347 -60.995 37.851  1.00 101.60 ? 284 GLU B O   1 
ATOM   5657  C CB  . GLU B 1 284 ? -17.987 -58.281 36.945  1.00 96.19  ? 284 GLU B CB  1 
ATOM   5658  C CG  . GLU B 1 284 ? -19.026 -59.322 37.325  1.00 103.78 ? 284 GLU B CG  1 
ATOM   5659  C CD  . GLU B 1 284 ? -20.039 -59.590 36.222  1.00 117.23 ? 284 GLU B CD  1 
ATOM   5660  O OE1 . GLU B 1 284 ? -20.788 -58.652 35.869  1.00 125.64 ? 284 GLU B OE1 1 
ATOM   5661  O OE2 . GLU B 1 284 ? -20.064 -60.729 35.689  1.00 112.68 ? 284 GLU B OE2 1 
ATOM   5662  N N   . THR B 1 285 ? -15.895 -60.453 35.700  1.00 95.84  ? 285 THR B N   1 
ATOM   5663  C CA  . THR B 1 285 ? -15.662 -61.811 35.214  1.00 92.64  ? 285 THR B CA  1 
ATOM   5664  C C   . THR B 1 285 ? -14.303 -62.361 35.673  1.00 93.85  ? 285 THR B C   1 
ATOM   5665  O O   . THR B 1 285 ? -14.239 -63.489 36.136  1.00 98.27  ? 285 THR B O   1 
ATOM   5666  C CB  . THR B 1 285 ? -15.833 -61.853 33.684  1.00 94.19  ? 285 THR B CB  1 
ATOM   5667  O OG1 . THR B 1 285 ? -17.235 -61.826 33.390  1.00 81.35  ? 285 THR B OG1 1 
ATOM   5668  C CG2 . THR B 1 285 ? -15.199 -63.060 33.022  1.00 95.94  ? 285 THR B CG2 1 
ATOM   5669  N N   . ILE B 1 286 ? -13.214 -61.595 35.510  1.00 92.55  ? 286 ILE B N   1 
ATOM   5670  C CA  . ILE B 1 286 ? -11.895 -61.958 36.025  1.00 83.39  ? 286 ILE B CA  1 
ATOM   5671  C C   . ILE B 1 286 ? -11.953 -62.223 37.528  1.00 86.89  ? 286 ILE B C   1 
ATOM   5672  O O   . ILE B 1 286 ? -11.183 -63.042 38.021  1.00 101.52 ? 286 ILE B O   1 
ATOM   5673  C CB  . ILE B 1 286 ? -10.858 -60.848 35.762  1.00 84.55  ? 286 ILE B CB  1 
ATOM   5674  C CG1 . ILE B 1 286 ? -10.569 -60.646 34.271  1.00 85.55  ? 286 ILE B CG1 1 
ATOM   5675  C CG2 . ILE B 1 286 ? -9.580  -61.103 36.557  1.00 77.94  ? 286 ILE B CG2 1 
ATOM   5676  C CD1 . ILE B 1 286 ? -9.728  -59.404 33.973  1.00 83.60  ? 286 ILE B CD1 1 
ATOM   5677  N N   . ASP B 1 287 ? -12.807 -61.484 38.252  1.00 91.38  ? 287 ASP B N   1 
ATOM   5678  C CA  . ASP B 1 287 ? -12.902 -61.571 39.702  1.00 94.51  ? 287 ASP B CA  1 
ATOM   5679  C C   . ASP B 1 287 ? -13.719 -62.797 40.131  1.00 110.78 ? 287 ASP B C   1 
ATOM   5680  O O   . ASP B 1 287 ? -13.269 -63.569 40.980  1.00 124.48 ? 287 ASP B O   1 
ATOM   5681  C CB  . ASP B 1 287 ? -13.521 -60.300 40.285  1.00 92.77  ? 287 ASP B CB  1 
ATOM   5682  C CG  . ASP B 1 287 ? -13.585 -60.319 41.805  1.00 102.04 ? 287 ASP B CG  1 
ATOM   5683  O OD1 . ASP B 1 287 ? -12.502 -60.240 42.434  1.00 94.49  ? 287 ASP B OD1 1 
ATOM   5684  O OD2 . ASP B 1 287 ? -14.713 -60.448 42.353  1.00 107.03 ? 287 ASP B OD2 1 
ATOM   5685  N N   . LYS B 1 288 ? -14.839 -63.034 39.456  1.00 112.22 ? 288 LYS B N   1 
ATOM   5686  C CA  . LYS B 1 288 ? -15.746 -64.105 39.930  1.00 115.87 ? 288 LYS B CA  1 
ATOM   5687  C C   . LYS B 1 288 ? -15.497 -65.460 39.276  1.00 120.95 ? 288 LYS B C   1 
ATOM   5688  O O   . LYS B 1 288 ? -15.108 -66.396 39.996  1.00 125.59 ? 288 LYS B O   1 
ATOM   5689  C CB  . LYS B 1 288 ? -17.178 -63.685 39.602  1.00 118.71 ? 288 LYS B CB  1 
ATOM   5690  C CG  . LYS B 1 288 ? -18.107 -63.552 40.800  1.00 119.92 ? 288 LYS B CG  1 
ATOM   5691  C CD  . LYS B 1 288 ? -17.466 -62.857 41.981  1.00 112.20 ? 288 LYS B CD  1 
ATOM   5692  C CE  . LYS B 1 288 ? -18.102 -61.520 42.292  1.00 105.69 ? 288 LYS B CE  1 
ATOM   5693  N NZ  . LYS B 1 288 ? -17.406 -60.410 41.600  1.00 111.50 ? 288 LYS B NZ  1 
ATOM   5694  N N   . LYS B 1 289 ? -15.680 -65.566 37.969  1.00 121.43 ? 289 LYS B N   1 
ATOM   5695  C CA  . LYS B 1 289 ? -15.659 -66.866 37.314  1.00 120.16 ? 289 LYS B CA  1 
ATOM   5696  C C   . LYS B 1 289 ? -14.244 -67.441 37.176  1.00 113.02 ? 289 LYS B C   1 
ATOM   5697  O O   . LYS B 1 289 ? -14.108 -68.661 37.087  1.00 114.66 ? 289 LYS B O   1 
ATOM   5698  C CB  . LYS B 1 289 ? -16.305 -66.765 35.925  1.00 125.58 ? 289 LYS B CB  1 
ATOM   5699  C CG  . LYS B 1 289 ? -17.800 -67.053 35.873  1.00 121.80 ? 289 LYS B CG  1 
ATOM   5700  C CD  . LYS B 1 289 ? -18.672 -66.045 36.594  1.00 109.98 ? 289 LYS B CD  1 
ATOM   5701  C CE  . LYS B 1 289 ? -20.148 -66.346 36.438  1.00 101.09 ? 289 LYS B CE  1 
ATOM   5702  N NZ  . LYS B 1 289 ? -20.924 -65.906 37.619  1.00 90.89  ? 289 LYS B NZ  1 
ATOM   5703  N N   . LEU B 1 290 ? -13.207 -66.582 37.131  1.00 102.60 ? 290 LEU B N   1 
ATOM   5704  C CA  . LEU B 1 290 ? -11.857 -67.014 36.783  1.00 96.36  ? 290 LEU B CA  1 
ATOM   5705  C C   . LEU B 1 290 ? -10.857 -66.657 37.883  1.00 89.37  ? 290 LEU B C   1 
ATOM   5706  O O   . LEU B 1 290 ? -9.655  -66.688 37.621  1.00 74.99  ? 290 LEU B O   1 
ATOM   5707  C CB  . LEU B 1 290 ? -11.455 -66.354 35.462  1.00 95.49  ? 290 LEU B CB  1 
ATOM   5708  C CG  . LEU B 1 290 ? -12.583 -66.180 34.443  1.00 104.17 ? 290 LEU B CG  1 
ATOM   5709  C CD1 . LEU B 1 290 ? -12.154 -65.203 33.356  1.00 111.15 ? 290 LEU B CD1 1 
ATOM   5710  C CD2 . LEU B 1 290 ? -13.026 -67.510 33.834  1.00 98.29  ? 290 LEU B CD2 1 
ATOM   5711  N N   . GLY B 1 291 ? -11.373 -66.267 39.068  1.00 85.93  ? 291 GLY B N   1 
ATOM   5712  C CA  . GLY B 1 291 ? -10.635 -66.222 40.326  1.00 95.68  ? 291 GLY B CA  1 
ATOM   5713  C C   . GLY B 1 291 ? -9.522  -65.169 40.405  1.00 101.97 ? 291 GLY B C   1 
ATOM   5714  O O   . GLY B 1 291 ? -8.443  -65.461 40.917  1.00 100.73 ? 291 GLY B O   1 
ATOM   5715  N N   . GLY B 1 292 ? -9.793  -63.941 39.939  1.00 103.66 ? 292 GLY B N   1 
ATOM   5716  C CA  . GLY B 1 292 ? -8.847  -62.833 40.008  1.00 104.13 ? 292 GLY B CA  1 
ATOM   5717  C C   . GLY B 1 292 ? -7.538  -63.089 39.256  1.00 100.94 ? 292 GLY B C   1 
ATOM   5718  O O   . GLY B 1 292 ? -6.503  -62.526 39.615  1.00 90.48  ? 292 GLY B O   1 
ATOM   5719  N N   . LYS B 1 293 ? -7.589  -63.929 38.212  1.00 99.67  ? 293 LYS B N   1 
ATOM   5720  C CA  . LYS B 1 293 ? -6.402  -64.312 37.455  1.00 95.33  ? 293 LYS B CA  1 
ATOM   5721  C C   . LYS B 1 293 ? -6.817  -64.488 35.991  1.00 100.13 ? 293 LYS B C   1 
ATOM   5722  O O   . LYS B 1 293 ? -7.965  -64.856 35.711  1.00 92.36  ? 293 LYS B O   1 
ATOM   5723  C CB  . LYS B 1 293 ? -5.727  -65.508 38.153  1.00 93.58  ? 293 LYS B CB  1 
ATOM   5724  C CG  . LYS B 1 293 ? -5.007  -66.571 37.313  1.00 103.15 ? 293 LYS B CG  1 
ATOM   5725  C CD  . LYS B 1 293 ? -4.016  -66.125 36.224  1.00 111.45 ? 293 LYS B CD  1 
ATOM   5726  C CE  . LYS B 1 293 ? -3.179  -64.900 36.530  1.00 112.71 ? 293 LYS B CE  1 
ATOM   5727  N NZ  . LYS B 1 293 ? -2.223  -65.187 37.621  1.00 118.69 ? 293 LYS B NZ  1 
ATOM   5728  N N   . VAL B 1 294 ? -5.890  -64.106 35.089  1.00 100.94 ? 294 VAL B N   1 
ATOM   5729  C CA  . VAL B 1 294 ? -5.997  -64.311 33.650  1.00 103.49 ? 294 VAL B CA  1 
ATOM   5730  C C   . VAL B 1 294 ? -6.340  -65.771 33.380  1.00 118.08 ? 294 VAL B C   1 
ATOM   5731  O O   . VAL B 1 294 ? -5.524  -66.649 33.648  1.00 126.73 ? 294 VAL B O   1 
ATOM   5732  C CB  . VAL B 1 294 ? -4.697  -63.932 32.907  1.00 103.06 ? 294 VAL B CB  1 
ATOM   5733  C CG1 . VAL B 1 294 ? -4.906  -63.932 31.388  1.00 96.02  ? 294 VAL B CG1 1 
ATOM   5734  C CG2 . VAL B 1 294 ? -4.114  -62.601 33.391  1.00 100.25 ? 294 VAL B CG2 1 
ATOM   5735  N N   . PRO B 1 295 ? -7.527  -66.090 32.816  1.00 131.65 ? 295 PRO B N   1 
ATOM   5736  C CA  . PRO B 1 295 ? -7.888  -67.483 32.564  1.00 134.10 ? 295 PRO B CA  1 
ATOM   5737  C C   . PRO B 1 295 ? -6.976  -68.087 31.500  1.00 141.50 ? 295 PRO B C   1 
ATOM   5738  O O   . PRO B 1 295 ? -6.253  -67.369 30.801  1.00 126.16 ? 295 PRO B O   1 
ATOM   5739  C CB  . PRO B 1 295 ? -9.347  -67.393 32.093  1.00 125.01 ? 295 PRO B CB  1 
ATOM   5740  C CG  . PRO B 1 295 ? -9.422  -66.033 31.450  1.00 126.90 ? 295 PRO B CG  1 
ATOM   5741  C CD  . PRO B 1 295 ? -8.563  -65.158 32.345  1.00 134.17 ? 295 PRO B CD  1 
ATOM   5742  N N   . THR B 1 296 ? -6.994  -69.425 31.437  1.00 141.92 ? 296 THR B N   1 
ATOM   5743  C CA  . THR B 1 296 ? -6.491  -70.142 30.280  1.00 137.51 ? 296 THR B CA  1 
ATOM   5744  C C   . THR B 1 296 ? -7.546  -70.026 29.180  1.00 132.85 ? 296 THR B C   1 
ATOM   5745  O O   . THR B 1 296 ? -8.705  -69.692 29.446  1.00 126.10 ? 296 THR B O   1 
ATOM   5746  C CB  . THR B 1 296 ? -6.126  -71.590 30.642  1.00 131.01 ? 296 THR B CB  1 
ATOM   5747  O OG1 . THR B 1 296 ? -7.319  -72.184 31.152  1.00 125.43 ? 296 THR B OG1 1 
ATOM   5748  C CG2 . THR B 1 296 ? -4.997  -71.708 31.650  1.00 117.14 ? 296 THR B CG2 1 
ATOM   5749  N N   . LYS B 1 297 ? -7.133  -70.313 27.942  1.00 125.31 ? 297 LYS B N   1 
ATOM   5750  C CA  . LYS B 1 297 ? -7.961  -70.090 26.766  1.00 120.61 ? 297 LYS B CA  1 
ATOM   5751  C C   . LYS B 1 297 ? -9.300  -70.828 26.910  1.00 117.42 ? 297 LYS B C   1 
ATOM   5752  O O   . LYS B 1 297 ? -10.293 -70.464 26.272  1.00 91.11  ? 297 LYS B O   1 
ATOM   5753  C CB  . LYS B 1 297 ? -7.157  -70.516 25.529  1.00 117.99 ? 297 LYS B CB  1 
ATOM   5754  C CG  . LYS B 1 297 ? -7.582  -69.865 24.222  1.00 116.36 ? 297 LYS B CG  1 
ATOM   5755  C CD  . LYS B 1 297 ? -7.103  -70.588 22.997  1.00 111.25 ? 297 LYS B CD  1 
ATOM   5756  C CE  . LYS B 1 297 ? -7.790  -70.078 21.749  1.00 110.82 ? 297 LYS B CE  1 
ATOM   5757  N NZ  . LYS B 1 297 ? -7.424  -70.878 20.558  1.00 109.58 ? 297 LYS B NZ  1 
ATOM   5758  N N   . GLU B 1 298 ? -9.331  -71.826 27.810  1.00 126.72 ? 298 GLU B N   1 
ATOM   5759  C CA  . GLU B 1 298 ? -10.331 -72.879 27.808  1.00 135.41 ? 298 GLU B CA  1 
ATOM   5760  C C   . GLU B 1 298 ? -11.496 -72.549 28.743  1.00 139.31 ? 298 GLU B C   1 
ATOM   5761  O O   . GLU B 1 298 ? -12.646 -72.811 28.398  1.00 134.73 ? 298 GLU B O   1 
ATOM   5762  C CB  . GLU B 1 298 ? -9.640  -74.186 28.222  1.00 139.06 ? 298 GLU B CB  1 
ATOM   5763  C CG  . GLU B 1 298 ? -9.976  -75.373 27.340  1.00 139.30 ? 298 GLU B CG  1 
ATOM   5764  C CD  . GLU B 1 298 ? -9.726  -75.129 25.858  1.00 151.35 ? 298 GLU B CD  1 
ATOM   5765  O OE1 . GLU B 1 298 ? -8.558  -74.877 25.485  1.00 159.06 ? 298 GLU B OE1 1 
ATOM   5766  O OE2 . GLU B 1 298 ? -10.703 -75.189 25.074  1.00 155.35 ? 298 GLU B OE2 1 
ATOM   5767  N N   . GLU B 1 299 ? -11.182 -72.018 29.936  1.00 133.31 ? 299 GLU B N   1 
ATOM   5768  C CA  . GLU B 1 299 ? -12.184 -71.634 30.919  1.00 123.89 ? 299 GLU B CA  1 
ATOM   5769  C C   . GLU B 1 299 ? -12.961 -70.421 30.423  1.00 123.41 ? 299 GLU B C   1 
ATOM   5770  O O   . GLU B 1 299 ? -14.116 -70.232 30.796  1.00 111.86 ? 299 GLU B O   1 
ATOM   5771  C CB  . GLU B 1 299 ? -11.526 -71.272 32.250  1.00 129.09 ? 299 GLU B CB  1 
ATOM   5772  C CG  . GLU B 1 299 ? -10.850 -72.445 32.929  1.00 133.04 ? 299 GLU B CG  1 
ATOM   5773  C CD  . GLU B 1 299 ? -9.701  -72.075 33.854  1.00 122.55 ? 299 GLU B CD  1 
ATOM   5774  O OE1 . GLU B 1 299 ? -9.316  -70.878 33.890  1.00 110.53 ? 299 GLU B OE1 1 
ATOM   5775  O OE2 . GLU B 1 299 ? -9.189  -72.989 34.531  1.00 103.36 ? 299 GLU B OE2 1 
ATOM   5776  N N   . LEU B 1 300 ? -12.292 -69.589 29.614  1.00 127.98 ? 300 LEU B N   1 
ATOM   5777  C CA  . LEU B 1 300 ? -12.949 -68.475 28.956  1.00 124.45 ? 300 LEU B CA  1 
ATOM   5778  C C   . LEU B 1 300 ? -13.842 -69.001 27.836  1.00 110.55 ? 300 LEU B C   1 
ATOM   5779  O O   . LEU B 1 300 ? -15.003 -68.599 27.751  1.00 94.83  ? 300 LEU B O   1 
ATOM   5780  C CB  . LEU B 1 300 ? -11.892 -67.502 28.421  1.00 133.01 ? 300 LEU B CB  1 
ATOM   5781  C CG  . LEU B 1 300 ? -12.444 -66.158 27.942  1.00 136.45 ? 300 LEU B CG  1 
ATOM   5782  C CD1 . LEU B 1 300 ? -13.083 -65.386 29.091  1.00 136.04 ? 300 LEU B CD1 1 
ATOM   5783  C CD2 . LEU B 1 300 ? -11.362 -65.318 27.283  1.00 135.21 ? 300 LEU B CD2 1 
ATOM   5784  N N   . LYS B 1 301 ? -13.294 -69.919 27.015  1.00 107.79 ? 301 LYS B N   1 
ATOM   5785  C CA  . LYS B 1 301 ? -13.983 -70.457 25.845  1.00 106.04 ? 301 LYS B CA  1 
ATOM   5786  C C   . LYS B 1 301 ? -15.369 -70.983 26.234  1.00 105.06 ? 301 LYS B C   1 
ATOM   5787  O O   . LYS B 1 301 ? -16.339 -70.746 25.513  1.00 95.08  ? 301 LYS B O   1 
ATOM   5788  C CB  . LYS B 1 301 ? -13.135 -71.532 25.150  1.00 84.64  ? 301 LYS B CB  1 
ATOM   5789  N N   . LYS B 1 302 ? -15.475 -71.670 27.382  1.00 110.76 ? 302 LYS B N   1 
ATOM   5790  C CA  . LYS B 1 302 ? -16.747 -72.255 27.797  1.00 120.52 ? 302 LYS B CA  1 
ATOM   5791  C C   . LYS B 1 302 ? -17.512 -71.296 28.719  1.00 127.09 ? 302 LYS B C   1 
ATOM   5792  O O   . LYS B 1 302 ? -18.697 -71.516 28.985  1.00 119.17 ? 302 LYS B O   1 
ATOM   5793  C CB  . LYS B 1 302 ? -16.533 -73.637 28.436  1.00 109.32 ? 302 LYS B CB  1 
ATOM   5794  C CG  . LYS B 1 302 ? -15.695 -73.670 29.706  1.00 108.91 ? 302 LYS B CG  1 
ATOM   5795  C CD  . LYS B 1 302 ? -16.181 -74.677 30.723  1.00 99.47  ? 302 LYS B CD  1 
ATOM   5796  C CE  . LYS B 1 302 ? -17.452 -74.201 31.392  1.00 90.48  ? 302 LYS B CE  1 
ATOM   5797  N NZ  . LYS B 1 302 ? -18.147 -75.282 32.124  1.00 88.61  ? 302 LYS B NZ  1 
ATOM   5798  N N   . PHE B 1 303 ? -16.851 -70.234 29.209  1.00 121.51 ? 303 PHE B N   1 
ATOM   5799  C CA  . PHE B 1 303 ? -17.530 -69.217 30.001  1.00 127.05 ? 303 PHE B CA  1 
ATOM   5800  C C   . PHE B 1 303 ? -18.464 -68.377 29.126  1.00 136.45 ? 303 PHE B C   1 
ATOM   5801  O O   . PHE B 1 303 ? -19.497 -67.908 29.598  1.00 127.76 ? 303 PHE B O   1 
ATOM   5802  C CB  . PHE B 1 303 ? -16.554 -68.279 30.717  1.00 123.40 ? 303 PHE B CB  1 
ATOM   5803  C CG  . PHE B 1 303 ? -17.260 -67.065 31.262  1.00 128.29 ? 303 PHE B CG  1 
ATOM   5804  C CD1 . PHE B 1 303 ? -18.203 -67.198 32.270  1.00 127.79 ? 303 PHE B CD1 1 
ATOM   5805  C CD2 . PHE B 1 303 ? -17.079 -65.815 30.690  1.00 126.90 ? 303 PHE B CD2 1 
ATOM   5806  C CE1 . PHE B 1 303 ? -18.903 -66.095 32.736  1.00 130.86 ? 303 PHE B CE1 1 
ATOM   5807  C CE2 . PHE B 1 303 ? -17.779 -64.712 31.162  1.00 130.75 ? 303 PHE B CE2 1 
ATOM   5808  C CZ  . PHE B 1 303 ? -18.689 -64.853 32.184  1.00 129.17 ? 303 PHE B CZ  1 
ATOM   5809  N N   . VAL B 1 304 ? -18.073 -68.155 27.864  1.00 147.74 ? 304 VAL B N   1 
ATOM   5810  C CA  . VAL B 1 304 ? -18.888 -67.405 26.918  1.00 152.21 ? 304 VAL B CA  1 
ATOM   5811  C C   . VAL B 1 304 ? -20.185 -68.180 26.654  1.00 152.44 ? 304 VAL B C   1 
ATOM   5812  O O   . VAL B 1 304 ? -21.261 -67.579 26.622  1.00 165.60 ? 304 VAL B O   1 
ATOM   5813  C CB  . VAL B 1 304 ? -18.117 -67.075 25.616  1.00 151.79 ? 304 VAL B CB  1 
ATOM   5814  C CG1 . VAL B 1 304 ? -18.994 -66.369 24.586  1.00 148.66 ? 304 VAL B CG1 1 
ATOM   5815  C CG2 . VAL B 1 304 ? -16.871 -66.240 25.870  1.00 144.93 ? 304 VAL B CG2 1 
ATOM   5816  N N   . GLU B 1 305 ? -20.084 -69.512 26.504  1.00 140.16 ? 305 GLU B N   1 
ATOM   5817  C CA  . GLU B 1 305 ? -21.234 -70.368 26.226  1.00 133.24 ? 305 GLU B CA  1 
ATOM   5818  C C   . GLU B 1 305 ? -22.264 -70.321 27.358  1.00 136.63 ? 305 GLU B C   1 
ATOM   5819  O O   . GLU B 1 305 ? -23.465 -70.359 27.080  1.00 141.12 ? 305 GLU B O   1 
ATOM   5820  C CB  . GLU B 1 305 ? -20.816 -71.826 26.047  1.00 131.49 ? 305 GLU B CB  1 
ATOM   5821  C CG  . GLU B 1 305 ? -19.996 -72.094 24.806  1.00 128.83 ? 305 GLU B CG  1 
ATOM   5822  C CD  . GLU B 1 305 ? -19.263 -73.428 24.846  1.00 126.11 ? 305 GLU B CD  1 
ATOM   5823  O OE1 . GLU B 1 305 ? -19.249 -74.089 25.916  1.00 109.24 ? 305 GLU B OE1 1 
ATOM   5824  O OE2 . GLU B 1 305 ? -18.737 -73.834 23.794  1.00 111.81 ? 305 GLU B OE2 1 
ATOM   5825  N N   . GLU B 1 306 ? -21.791 -70.266 28.620  1.00 136.77 ? 306 GLU B N   1 
ATOM   5826  C CA  . GLU B 1 306 ? -22.670 -70.180 29.782  1.00 136.09 ? 306 GLU B CA  1 
ATOM   5827  C C   . GLU B 1 306 ? -23.474 -68.873 29.749  1.00 140.44 ? 306 GLU B C   1 
ATOM   5828  O O   . GLU B 1 306 ? -24.688 -68.904 29.960  1.00 126.77 ? 306 GLU B O   1 
ATOM   5829  C CB  . GLU B 1 306 ? -21.898 -70.315 31.107  1.00 130.43 ? 306 GLU B CB  1 
ATOM   5830  C CG  . GLU B 1 306 ? -21.315 -71.703 31.385  1.00 126.90 ? 306 GLU B CG  1 
ATOM   5831  C CD  . GLU B 1 306 ? -20.934 -72.022 32.831  1.00 118.33 ? 306 GLU B CD  1 
ATOM   5832  O OE1 . GLU B 1 306 ? -21.503 -71.396 33.756  1.00 110.69 ? 306 GLU B OE1 1 
ATOM   5833  O OE2 . GLU B 1 306 ? -20.060 -72.903 33.038  1.00 94.43  ? 306 GLU B OE2 1 
ATOM   5834  N N   . THR B 1 307 ? -22.809 -67.733 29.474  1.00 138.28 ? 307 THR B N   1 
ATOM   5835  C CA  . THR B 1 307 ? -23.464 -66.429 29.424  1.00 125.83 ? 307 THR B CA  1 
ATOM   5836  C C   . THR B 1 307 ? -24.475 -66.377 28.277  1.00 123.66 ? 307 THR B C   1 
ATOM   5837  O O   . THR B 1 307 ? -25.509 -65.713 28.401  1.00 119.41 ? 307 THR B O   1 
ATOM   5838  C CB  . THR B 1 307 ? -22.479 -65.259 29.229  1.00 113.27 ? 307 THR B CB  1 
ATOM   5839  O OG1 . THR B 1 307 ? -21.270 -65.462 29.966  1.00 103.05 ? 307 THR B OG1 1 
ATOM   5840  C CG2 . THR B 1 307 ? -23.081 -63.922 29.617  1.00 103.83 ? 307 THR B CG2 1 
ATOM   5841  N N   . LEU B 1 308 ? -24.153 -67.061 27.163  1.00 114.51 ? 308 LEU B N   1 
ATOM   5842  C CA  . LEU B 1 308 ? -24.891 -66.916 25.915  1.00 117.15 ? 308 LEU B CA  1 
ATOM   5843  C C   . LEU B 1 308 ? -26.159 -67.765 25.927  1.00 124.00 ? 308 LEU B C   1 
ATOM   5844  O O   . LEU B 1 308 ? -27.251 -67.238 25.713  1.00 99.95  ? 308 LEU B O   1 
ATOM   5845  C CB  . LEU B 1 308 ? -24.006 -67.304 24.723  1.00 106.46 ? 308 LEU B CB  1 
ATOM   5846  C CG  . LEU B 1 308 ? -23.204 -66.174 24.074  1.00 98.34  ? 308 LEU B CG  1 
ATOM   5847  C CD1 . LEU B 1 308 ? -22.570 -66.654 22.774  1.00 88.15  ? 308 LEU B CD1 1 
ATOM   5848  C CD2 . LEU B 1 308 ? -24.069 -64.933 23.833  1.00 93.22  ? 308 LEU B CD2 1 
ATOM   5849  N N   . SER B 1 309 ? -26.005 -69.077 26.156  1.00 141.49 ? 309 SER B N   1 
ATOM   5850  C CA  . SER B 1 309 ? -27.133 -69.997 26.082  1.00 140.42 ? 309 SER B CA  1 
ATOM   5851  C C   . SER B 1 309 ? -27.950 -69.981 27.381  1.00 133.86 ? 309 SER B C   1 
ATOM   5852  O O   . SER B 1 309 ? -28.824 -70.829 27.560  1.00 128.24 ? 309 SER B O   1 
ATOM   5853  C CB  . SER B 1 309 ? -26.685 -71.391 25.684  1.00 128.14 ? 309 SER B CB  1 
ATOM   5854  O OG  . SER B 1 309 ? -25.580 -71.820 26.458  1.00 134.67 ? 309 SER B OG  1 
ATOM   5855  N N   . SER B 1 310 ? -27.684 -69.002 28.269  1.00 132.92 ? 310 SER B N   1 
ATOM   5856  C CA  . SER B 1 310 ? -28.591 -68.663 29.364  1.00 124.10 ? 310 SER B CA  1 
ATOM   5857  C C   . SER B 1 310 ? -29.173 -67.249 29.194  1.00 121.17 ? 310 SER B C   1 
ATOM   5858  O O   . SER B 1 310 ? -29.695 -66.680 30.150  1.00 110.17 ? 310 SER B O   1 
ATOM   5859  C CB  . SER B 1 310 ? -27.928 -68.868 30.728  1.00 109.68 ? 310 SER B CB  1 
ATOM   5860  O OG  . SER B 1 310 ? -26.885 -67.933 30.969  1.00 87.78  ? 310 SER B OG  1 
ATOM   5861  N N   . GLY B 1 311 ? -29.091 -66.689 27.974  1.00 124.03 ? 311 GLY B N   1 
ATOM   5862  C CA  . GLY B 1 311 ? -29.930 -65.574 27.552  1.00 130.98 ? 311 GLY B CA  1 
ATOM   5863  C C   . GLY B 1 311 ? -29.385 -64.191 27.921  1.00 140.27 ? 311 GLY B C   1 
ATOM   5864  O O   . GLY B 1 311 ? -30.102 -63.406 28.544  1.00 138.02 ? 311 GLY B O   1 
ATOM   5865  N N   . GLN B 1 312 ? -28.145 -63.891 27.488  1.00 147.15 ? 312 GLN B N   1 
ATOM   5866  C CA  . GLN B 1 312 ? -27.516 -62.595 27.729  1.00 143.85 ? 312 GLN B CA  1 
ATOM   5867  C C   . GLN B 1 312 ? -26.485 -62.247 26.647  1.00 139.99 ? 312 GLN B C   1 
ATOM   5868  O O   . GLN B 1 312 ? -25.814 -63.134 26.115  1.00 137.43 ? 312 GLN B O   1 
ATOM   5869  C CB  . GLN B 1 312 ? -26.869 -62.584 29.115  1.00 132.93 ? 312 GLN B CB  1 
ATOM   5870  C CG  . GLN B 1 312 ? -27.886 -62.467 30.245  1.00 113.81 ? 312 GLN B CG  1 
ATOM   5871  C CD  . GLN B 1 312 ? -27.281 -61.711 31.395  1.00 105.32 ? 312 GLN B CD  1 
ATOM   5872  O OE1 . GLN B 1 312 ? -26.168 -62.003 31.823  1.00 111.21 ? 312 GLN B OE1 1 
ATOM   5873  N NE2 . GLN B 1 312 ? -27.981 -60.694 31.867  1.00 97.89  ? 312 GLN B NE2 1 
ATOM   5874  N N   . VAL B 1 313 ? -26.356 -60.932 26.362  1.00 131.01 ? 313 VAL B N   1 
ATOM   5875  C CA  . VAL B 1 313 ? -25.440 -60.399 25.352  1.00 126.11 ? 313 VAL B CA  1 
ATOM   5876  C C   . VAL B 1 313 ? -23.992 -60.525 25.851  1.00 130.32 ? 313 VAL B C   1 
ATOM   5877  O O   . VAL B 1 313 ? -23.752 -60.719 27.041  1.00 110.20 ? 313 VAL B O   1 
ATOM   5878  C CB  . VAL B 1 313 ? -25.753 -58.937 24.917  1.00 104.87 ? 313 VAL B CB  1 
ATOM   5879  C CG1 . VAL B 1 313 ? -27.066 -58.802 24.149  1.00 90.57  ? 313 VAL B CG1 1 
ATOM   5880  C CG2 . VAL B 1 313 ? -25.692 -57.925 26.061  1.00 98.55  ? 313 VAL B CG2 1 
ATOM   5881  N N   . ILE B 1 314 ? -23.043 -60.487 24.899  1.00 138.80 ? 314 ILE B N   1 
ATOM   5882  C CA  . ILE B 1 314 ? -21.643 -60.157 25.148  1.00 143.51 ? 314 ILE B CA  1 
ATOM   5883  C C   . ILE B 1 314 ? -21.460 -58.680 24.776  1.00 152.45 ? 314 ILE B C   1 
ATOM   5884  O O   . ILE B 1 314 ? -21.626 -58.322 23.605  1.00 164.79 ? 314 ILE B O   1 
ATOM   5885  C CB  . ILE B 1 314 ? -20.687 -61.067 24.338  1.00 140.17 ? 314 ILE B CB  1 
ATOM   5886  C CG1 . ILE B 1 314 ? -21.007 -62.555 24.509  1.00 147.67 ? 314 ILE B CG1 1 
ATOM   5887  C CG2 . ILE B 1 314 ? -19.223 -60.773 24.664  1.00 126.69 ? 314 ILE B CG2 1 
ATOM   5888  C CD1 . ILE B 1 314 ? -20.609 -63.123 25.853  1.00 155.76 ? 314 ILE B CD1 1 
ATOM   5889  N N   . PRO B 1 315 ? -21.145 -57.760 25.728  1.00 129.44 ? 315 PRO B N   1 
ATOM   5890  C CA  . PRO B 1 315 ? -21.070 -56.327 25.417  1.00 110.50 ? 315 PRO B CA  1 
ATOM   5891  C C   . PRO B 1 315 ? -19.853 -55.940 24.572  1.00 100.22 ? 315 PRO B C   1 
ATOM   5892  O O   . PRO B 1 315 ? -18.766 -56.495 24.735  1.00 82.29  ? 315 PRO B O   1 
ATOM   5893  C CB  . PRO B 1 315 ? -21.019 -55.646 26.796  1.00 109.29 ? 315 PRO B CB  1 
ATOM   5894  C CG  . PRO B 1 315 ? -21.363 -56.741 27.790  1.00 116.45 ? 315 PRO B CG  1 
ATOM   5895  C CD  . PRO B 1 315 ? -20.876 -58.024 27.149  1.00 118.73 ? 315 PRO B CD  1 
ATOM   5896  N N   . GLY B 1 316 ? -20.060 -54.995 23.643  1.00 95.51  ? 316 GLY B N   1 
ATOM   5897  C CA  . GLY B 1 316 ? -19.003 -54.522 22.761  1.00 93.29  ? 316 GLY B CA  1 
ATOM   5898  C C   . GLY B 1 316 ? -18.754 -55.454 21.577  1.00 89.57  ? 316 GLY B C   1 
ATOM   5899  O O   . GLY B 1 316 ? -17.794 -55.271 20.832  1.00 84.14  ? 316 GLY B O   1 
ATOM   5900  N N   . TYR B 1 317 ? -19.609 -56.474 21.438  1.00 101.25 ? 317 TYR B N   1 
ATOM   5901  C CA  . TYR B 1 317 ? -19.779 -57.213 20.194  1.00 95.95  ? 317 TYR B CA  1 
ATOM   5902  C C   . TYR B 1 317 ? -21.171 -56.860 19.663  1.00 97.35  ? 317 TYR B C   1 
ATOM   5903  O O   . TYR B 1 317 ? -22.126 -56.884 20.440  1.00 102.54 ? 317 TYR B O   1 
ATOM   5904  C CB  . TYR B 1 317 ? -19.528 -58.710 20.436  1.00 82.16  ? 317 TYR B CB  1 
ATOM   5905  C CG  . TYR B 1 317 ? -18.087 -59.045 20.748  1.00 83.56  ? 317 TYR B CG  1 
ATOM   5906  C CD1 . TYR B 1 317 ? -17.505 -58.748 21.978  1.00 81.30  ? 317 TYR B CD1 1 
ATOM   5907  C CD2 . TYR B 1 317 ? -17.272 -59.625 19.785  1.00 91.32  ? 317 TYR B CD2 1 
ATOM   5908  C CE1 . TYR B 1 317 ? -16.167 -59.039 22.243  1.00 85.57  ? 317 TYR B CE1 1 
ATOM   5909  C CE2 . TYR B 1 317 ? -15.932 -59.919 20.030  1.00 89.71  ? 317 TYR B CE2 1 
ATOM   5910  C CZ  . TYR B 1 317 ? -15.367 -59.626 21.263  1.00 85.35  ? 317 TYR B CZ  1 
ATOM   5911  O OH  . TYR B 1 317 ? -14.024 -59.926 21.462  1.00 73.07  ? 317 TYR B OH  1 
ATOM   5912  N N   . GLY B 1 318 ? -21.262 -56.435 18.388  1.00 91.10  ? 318 GLY B N   1 
ATOM   5913  C CA  . GLY B 1 318 ? -22.539 -56.255 17.699  1.00 89.50  ? 318 GLY B CA  1 
ATOM   5914  C C   . GLY B 1 318 ? -22.939 -54.789 17.500  1.00 85.74  ? 318 GLY B C   1 
ATOM   5915  O O   . GLY B 1 318 ? -22.880 -54.004 18.438  1.00 87.35  ? 318 GLY B O   1 
ATOM   5916  N N   . HIS B 1 319 ? -23.406 -54.448 16.289  1.00 79.30  ? 319 HIS B N   1 
ATOM   5917  C CA  . HIS B 1 319 ? -23.624 -53.068 15.872  1.00 81.71  ? 319 HIS B CA  1 
ATOM   5918  C C   . HIS B 1 319 ? -24.750 -53.011 14.831  1.00 79.55  ? 319 HIS B C   1 
ATOM   5919  O O   . HIS B 1 319 ? -24.968 -53.966 14.089  1.00 73.03  ? 319 HIS B O   1 
ATOM   5920  C CB  . HIS B 1 319 ? -22.308 -52.494 15.324  1.00 80.72  ? 319 HIS B CB  1 
ATOM   5921  C CG  . HIS B 1 319 ? -22.213 -50.997 15.202  1.00 87.21  ? 319 HIS B CG  1 
ATOM   5922  N ND1 . HIS B 1 319 ? -22.762 -50.270 14.169  1.00 80.04  ? 319 HIS B ND1 1 
ATOM   5923  C CD2 . HIS B 1 319 ? -21.539 -50.106 15.990  1.00 86.68  ? 319 HIS B CD2 1 
ATOM   5924  C CE1 . HIS B 1 319 ? -22.439 -48.987 14.304  1.00 81.19  ? 319 HIS B CE1 1 
ATOM   5925  N NE2 . HIS B 1 319 ? -21.681 -48.860 15.434  1.00 87.19  ? 319 HIS B NE2 1 
ATOM   5926  N N   . ALA B 1 320 ? -25.449 -51.868 14.749  1.00 76.41  ? 320 ALA B N   1 
ATOM   5927  C CA  . ALA B 1 320 ? -26.657 -51.767 13.934  1.00 76.32  ? 320 ALA B CA  1 
ATOM   5928  C C   . ALA B 1 320 ? -26.360 -51.489 12.454  1.00 79.70  ? 320 ALA B C   1 
ATOM   5929  O O   . ALA B 1 320 ? -27.292 -51.304 11.670  1.00 77.98  ? 320 ALA B O   1 
ATOM   5930  C CB  . ALA B 1 320 ? -27.580 -50.718 14.513  1.00 79.75  ? 320 ALA B CB  1 
ATOM   5931  N N   . VAL B 1 321 ? -25.080 -51.452 12.066  1.00 88.99  ? 321 VAL B N   1 
ATOM   5932  C CA  . VAL B 1 321 ? -24.700 -51.279 10.625  1.00 84.76  ? 321 VAL B CA  1 
ATOM   5933  C C   . VAL B 1 321 ? -23.529 -52.218 10.330  1.00 78.48  ? 321 VAL B C   1 
ATOM   5934  O O   . VAL B 1 321 ? -23.664 -53.060 9.439   1.00 87.31  ? 321 VAL B O   1 
ATOM   5935  C CB  . VAL B 1 321 ? -24.319 -49.826 10.291  1.00 75.28  ? 321 VAL B CB  1 
ATOM   5936  C CG1 . VAL B 1 321 ? -23.927 -49.672 8.832   1.00 67.68  ? 321 VAL B CG1 1 
ATOM   5937  C CG2 . VAL B 1 321 ? -25.397 -48.825 10.673  1.00 72.41  ? 321 VAL B CG2 1 
ATOM   5938  N N   . LEU B 1 322 ? -22.423 -52.059 11.042  1.00 70.96  ? 322 LEU B N   1 
ATOM   5939  C CA  . LEU B 1 322 ? -21.257 -52.920 10.928  1.00 70.59  ? 322 LEU B CA  1 
ATOM   5940  C C   . LEU B 1 322 ? -21.671 -54.381 10.910  1.00 77.15  ? 322 LEU B C   1 
ATOM   5941  O O   . LEU B 1 322 ? -22.533 -54.765 11.699  1.00 61.82  ? 322 LEU B O   1 
ATOM   5942  C CB  . LEU B 1 322 ? -20.328 -52.683 12.121  1.00 68.94  ? 322 LEU B CB  1 
ATOM   5943  C CG  . LEU B 1 322 ? -19.302 -51.565 11.939  1.00 74.16  ? 322 LEU B CG  1 
ATOM   5944  C CD1 . LEU B 1 322 ? -18.601 -51.263 13.262  1.00 68.19  ? 322 LEU B CD1 1 
ATOM   5945  C CD2 . LEU B 1 322 ? -18.288 -51.940 10.853  1.00 78.98  ? 322 LEU B CD2 1 
ATOM   5946  N N   . ARG B 1 323 ? -21.030 -55.151 10.004  1.00 91.11  ? 323 ARG B N   1 
ATOM   5947  C CA  . ARG B 1 323 ? -21.152 -56.602 9.926   1.00 85.41  ? 323 ARG B CA  1 
ATOM   5948  C C   . ARG B 1 323 ? -19.788 -57.272 10.125  1.00 87.94  ? 323 ARG B C   1 
ATOM   5949  O O   . ARG B 1 323 ? -19.724 -58.491 10.252  1.00 80.95  ? 323 ARG B O   1 
ATOM   5950  C CB  . ARG B 1 323 ? -21.778 -57.032 8.589   1.00 84.00  ? 323 ARG B CB  1 
ATOM   5951  C CG  . ARG B 1 323 ? -23.272 -57.336 8.628   1.00 88.83  ? 323 ARG B CG  1 
ATOM   5952  C CD  . ARG B 1 323 ? -24.147 -56.102 8.480   1.00 100.23 ? 323 ARG B CD  1 
ATOM   5953  N NE  . ARG B 1 323 ? -25.495 -56.268 9.033   1.00 108.89 ? 323 ARG B NE  1 
ATOM   5954  C CZ  . ARG B 1 323 ? -26.022 -55.540 10.022  1.00 99.92  ? 323 ARG B CZ  1 
ATOM   5955  N NH1 . ARG B 1 323 ? -25.258 -55.030 10.972  1.00 99.42  ? 323 ARG B NH1 1 
ATOM   5956  N NH2 . ARG B 1 323 ? -27.331 -55.362 10.086  1.00 88.90  ? 323 ARG B NH2 1 
ATOM   5957  N N   . LYS B 1 324 ? -18.697 -56.495 10.197  1.00 103.77 ? 324 LYS B N   1 
ATOM   5958  C CA  . LYS B 1 324 ? -17.372 -57.063 10.423  1.00 107.33 ? 324 LYS B CA  1 
ATOM   5959  C C   . LYS B 1 324 ? -16.679 -56.437 11.638  1.00 104.21 ? 324 LYS B C   1 
ATOM   5960  O O   . LYS B 1 324 ? -17.246 -55.576 12.323  1.00 95.56  ? 324 LYS B O   1 
ATOM   5961  C CB  . LYS B 1 324 ? -16.488 -56.824 9.197   1.00 113.70 ? 324 LYS B CB  1 
ATOM   5962  C CG  . LYS B 1 324 ? -16.914 -57.542 7.934   1.00 111.44 ? 324 LYS B CG  1 
ATOM   5963  C CD  . LYS B 1 324 ? -16.772 -59.039 8.018   1.00 101.43 ? 324 LYS B CD  1 
ATOM   5964  C CE  . LYS B 1 324 ? -16.572 -59.665 6.658   1.00 97.99  ? 324 LYS B CE  1 
ATOM   5965  N NZ  . LYS B 1 324 ? -17.350 -60.919 6.554   1.00 107.35 ? 324 LYS B NZ  1 
ATOM   5966  N N   . THR B 1 325 ? -15.445 -56.913 11.891  1.00 98.20  ? 325 THR B N   1 
ATOM   5967  C CA  . THR B 1 325 ? -14.542 -56.322 12.868  1.00 99.25  ? 325 THR B CA  1 
ATOM   5968  C C   . THR B 1 325 ? -14.498 -54.821 12.601  1.00 91.19  ? 325 THR B C   1 
ATOM   5969  O O   . THR B 1 325 ? -14.378 -54.418 11.445  1.00 91.03  ? 325 THR B O   1 
ATOM   5970  C CB  . THR B 1 325 ? -13.141 -56.969 12.823  1.00 102.41 ? 325 THR B CB  1 
ATOM   5971  O OG1 . THR B 1 325 ? -13.203 -58.377 13.066  1.00 95.07  ? 325 THR B OG1 1 
ATOM   5972  C CG2 . THR B 1 325 ? -12.176 -56.402 13.843  1.00 101.88 ? 325 THR B CG2 1 
ATOM   5973  N N   . ASP B 1 326 ? -14.636 -54.011 13.665  1.00 79.87  ? 326 ASP B N   1 
ATOM   5974  C CA  . ASP B 1 326 ? -14.448 -52.569 13.571  1.00 81.65  ? 326 ASP B CA  1 
ATOM   5975  C C   . ASP B 1 326 ? -12.960 -52.249 13.441  1.00 71.23  ? 326 ASP B C   1 
ATOM   5976  O O   . ASP B 1 326 ? -12.183 -52.586 14.324  1.00 82.22  ? 326 ASP B O   1 
ATOM   5977  C CB  . ASP B 1 326 ? -15.033 -51.858 14.795  1.00 80.64  ? 326 ASP B CB  1 
ATOM   5978  C CG  . ASP B 1 326 ? -15.230 -50.354 14.654  1.00 80.78  ? 326 ASP B CG  1 
ATOM   5979  O OD1 . ASP B 1 326 ? -14.735 -49.750 13.660  1.00 90.85  ? 326 ASP B OD1 1 
ATOM   5980  O OD2 . ASP B 1 326 ? -15.915 -49.801 15.521  1.00 74.82  ? 326 ASP B OD2 1 
ATOM   5981  N N   . PRO B 1 327 ? -12.501 -51.562 12.371  1.00 68.19  ? 327 PRO B N   1 
ATOM   5982  C CA  . PRO B 1 327 ? -11.077 -51.210 12.255  1.00 75.94  ? 327 PRO B CA  1 
ATOM   5983  C C   . PRO B 1 327 ? -10.599 -50.198 13.302  1.00 82.14  ? 327 PRO B C   1 
ATOM   5984  O O   . PRO B 1 327 ? -9.388  -50.004 13.493  1.00 79.00  ? 327 PRO B O   1 
ATOM   5985  C CB  . PRO B 1 327 ? -10.989 -50.585 10.854  1.00 73.77  ? 327 PRO B CB  1 
ATOM   5986  C CG  . PRO B 1 327 ? -12.392 -50.043 10.607  1.00 72.62  ? 327 PRO B CG  1 
ATOM   5987  C CD  . PRO B 1 327 ? -13.317 -51.055 11.251  1.00 68.92  ? 327 PRO B CD  1 
ATOM   5988  N N   . ARG B 1 328 ? -11.578 -49.516 13.926  1.00 80.10  ? 328 ARG B N   1 
ATOM   5989  C CA  . ARG B 1 328 ? -11.343 -48.698 15.102  1.00 70.69  ? 328 ARG B CA  1 
ATOM   5990  C C   . ARG B 1 328 ? -10.944 -49.597 16.265  1.00 71.74  ? 328 ARG B C   1 
ATOM   5991  O O   . ARG B 1 328 ? -10.005 -49.261 16.981  1.00 63.31  ? 328 ARG B O   1 
ATOM   5992  C CB  . ARG B 1 328 ? -12.580 -47.871 15.450  1.00 64.46  ? 328 ARG B CB  1 
ATOM   5993  C CG  . ARG B 1 328 ? -12.962 -46.855 14.388  1.00 61.15  ? 328 ARG B CG  1 
ATOM   5994  C CD  . ARG B 1 328 ? -14.139 -46.000 14.799  1.00 65.48  ? 328 ARG B CD  1 
ATOM   5995  N NE  . ARG B 1 328 ? -15.350 -46.781 15.033  1.00 75.45  ? 328 ARG B NE  1 
ATOM   5996  C CZ  . ARG B 1 328 ? -16.459 -46.290 15.580  1.00 82.37  ? 328 ARG B CZ  1 
ATOM   5997  N NH1 . ARG B 1 328 ? -16.579 -44.984 15.764  1.00 98.64  ? 328 ARG B NH1 1 
ATOM   5998  N NH2 . ARG B 1 328 ? -17.443 -47.099 15.932  1.00 79.83  ? 328 ARG B NH2 1 
ATOM   5999  N N   . TYR B 1 329 ? -11.649 -50.731 16.441  1.00 75.78  ? 329 TYR B N   1 
ATOM   6000  C CA  . TYR B 1 329 ? -11.232 -51.764 17.389  1.00 76.43  ? 329 TYR B CA  1 
ATOM   6001  C C   . TYR B 1 329 ? -9.782  -52.177 17.087  1.00 73.52  ? 329 TYR B C   1 
ATOM   6002  O O   . TYR B 1 329 ? -8.908  -52.130 17.958  1.00 72.84  ? 329 TYR B O   1 
ATOM   6003  C CB  . TYR B 1 329 ? -12.224 -52.943 17.409  1.00 71.09  ? 329 TYR B CB  1 
ATOM   6004  C CG  . TYR B 1 329 ? -11.795 -54.089 18.299  1.00 74.09  ? 329 TYR B CG  1 
ATOM   6005  C CD1 . TYR B 1 329 ? -10.764 -54.942 17.929  1.00 75.72  ? 329 TYR B CD1 1 
ATOM   6006  C CD2 . TYR B 1 329 ? -12.358 -54.284 19.552  1.00 74.89  ? 329 TYR B CD2 1 
ATOM   6007  C CE1 . TYR B 1 329 ? -10.330 -55.965 18.759  1.00 76.13  ? 329 TYR B CE1 1 
ATOM   6008  C CE2 . TYR B 1 329 ? -11.941 -55.308 20.393  1.00 73.98  ? 329 TYR B CE2 1 
ATOM   6009  C CZ  . TYR B 1 329 ? -10.919 -56.159 19.999  1.00 79.95  ? 329 TYR B CZ  1 
ATOM   6010  O OH  . TYR B 1 329 ? -10.473 -57.179 20.837  1.00 72.68  ? 329 TYR B OH  1 
ATOM   6011  N N   . VAL B 1 330 ? -9.516  -52.537 15.825  1.00 74.41  ? 330 VAL B N   1 
ATOM   6012  C CA  . VAL B 1 330 ? -8.219  -53.059 15.423  1.00 77.51  ? 330 VAL B CA  1 
ATOM   6013  C C   . VAL B 1 330 ? -7.101  -52.070 15.782  1.00 76.68  ? 330 VAL B C   1 
ATOM   6014  O O   . VAL B 1 330 ? -6.016  -52.506 16.160  1.00 76.39  ? 330 VAL B O   1 
ATOM   6015  C CB  . VAL B 1 330 ? -8.200  -53.404 13.920  1.00 80.26  ? 330 VAL B CB  1 
ATOM   6016  C CG1 . VAL B 1 330 ? -6.815  -53.838 13.456  1.00 84.16  ? 330 VAL B CG1 1 
ATOM   6017  C CG2 . VAL B 1 330 ? -9.260  -54.439 13.557  1.00 78.72  ? 330 VAL B CG2 1 
ATOM   6018  N N   . ALA B 1 331 ? -7.351  -50.754 15.653  1.00 75.16  ? 331 ALA B N   1 
ATOM   6019  C CA  . ALA B 1 331 ? -6.331  -49.737 15.890  1.00 69.45  ? 331 ALA B CA  1 
ATOM   6020  C C   . ALA B 1 331 ? -6.024  -49.615 17.382  1.00 68.03  ? 331 ALA B C   1 
ATOM   6021  O O   . ALA B 1 331 ? -4.913  -49.219 17.753  1.00 63.31  ? 331 ALA B O   1 
ATOM   6022  C CB  . ALA B 1 331 ? -6.772  -48.414 15.314  1.00 62.50  ? 331 ALA B CB  1 
ATOM   6023  N N   . GLN B 1 332 ? -7.023  -49.940 18.222  1.00 71.44  ? 332 GLN B N   1 
ATOM   6024  C CA  . GLN B 1 332 ? -6.851  -49.957 19.670  1.00 76.10  ? 332 GLN B CA  1 
ATOM   6025  C C   . GLN B 1 332 ? -5.924  -51.117 20.018  1.00 78.47  ? 332 GLN B C   1 
ATOM   6026  O O   . GLN B 1 332 ? -4.924  -50.929 20.715  1.00 70.01  ? 332 GLN B O   1 
ATOM   6027  C CB  . GLN B 1 332 ? -8.179  -50.131 20.425  1.00 80.50  ? 332 GLN B CB  1 
ATOM   6028  C CG  . GLN B 1 332 ? -9.219  -49.036 20.191  1.00 86.44  ? 332 GLN B CG  1 
ATOM   6029  C CD  . GLN B 1 332 ? -8.941  -47.762 20.951  1.00 95.76  ? 332 GLN B CD  1 
ATOM   6030  O OE1 . GLN B 1 332 ? -7.818  -47.261 20.978  1.00 109.97 ? 332 GLN B OE1 1 
ATOM   6031  N NE2 . GLN B 1 332 ? -9.972  -47.221 21.579  1.00 98.37  ? 332 GLN B NE2 1 
ATOM   6032  N N   . ARG B 1 333 ? -6.284  -52.299 19.488  1.00 84.36  ? 333 ARG B N   1 
ATOM   6033  C CA  . ARG B 1 333 ? -5.515  -53.529 19.620  1.00 82.33  ? 333 ARG B CA  1 
ATOM   6034  C C   . ARG B 1 333 ? -4.038  -53.310 19.265  1.00 75.79  ? 333 ARG B C   1 
ATOM   6035  O O   . ARG B 1 333 ? -3.163  -53.844 19.941  1.00 65.01  ? 333 ARG B O   1 
ATOM   6036  C CB  . ARG B 1 333 ? -6.180  -54.617 18.766  1.00 87.81  ? 333 ARG B CB  1 
ATOM   6037  C CG  . ARG B 1 333 ? -5.513  -55.981 18.883  1.00 98.59  ? 333 ARG B CG  1 
ATOM   6038  C CD  . ARG B 1 333 ? -6.166  -57.077 18.052  1.00 99.53  ? 333 ARG B CD  1 
ATOM   6039  N NE  . ARG B 1 333 ? -5.459  -58.345 18.199  1.00 89.06  ? 333 ARG B NE  1 
ATOM   6040  C CZ  . ARG B 1 333 ? -5.261  -58.968 19.359  1.00 84.98  ? 333 ARG B CZ  1 
ATOM   6041  N NH1 . ARG B 1 333 ? -6.244  -59.134 20.228  1.00 83.98  ? 333 ARG B NH1 1 
ATOM   6042  N NH2 . ARG B 1 333 ? -4.067  -59.450 19.634  1.00 88.17  ? 333 ARG B NH2 1 
ATOM   6043  N N   . GLU B 1 334 ? -3.750  -52.492 18.245  1.00 81.27  ? 334 GLU B N   1 
ATOM   6044  C CA  . GLU B 1 334 ? -2.383  -52.302 17.775  1.00 79.41  ? 334 GLU B CA  1 
ATOM   6045  C C   . GLU B 1 334 ? -1.585  -51.441 18.748  1.00 75.75  ? 334 GLU B C   1 
ATOM   6046  O O   . GLU B 1 334 ? -0.426  -51.748 19.022  1.00 80.76  ? 334 GLU B O   1 
ATOM   6047  C CB  . GLU B 1 334 ? -2.384  -51.712 16.368  1.00 81.79  ? 334 GLU B CB  1 
ATOM   6048  C CG  . GLU B 1 334 ? -3.196  -52.565 15.406  1.00 90.85  ? 334 GLU B CG  1 
ATOM   6049  C CD  . GLU B 1 334 ? -2.773  -52.550 13.946  1.00 97.38  ? 334 GLU B CD  1 
ATOM   6050  O OE1 . GLU B 1 334 ? -3.485  -53.175 13.132  1.00 94.37  ? 334 GLU B OE1 1 
ATOM   6051  O OE2 . GLU B 1 334 ? -1.730  -51.928 13.623  1.00 110.02 ? 334 GLU B OE2 1 
ATOM   6052  N N   . PHE B 1 335 ? -2.217  -50.381 19.269  1.00 75.43  ? 335 PHE B N   1 
ATOM   6053  C CA  . PHE B 1 335 ? -1.646  -49.593 20.349  1.00 69.79  ? 335 PHE B CA  1 
ATOM   6054  C C   . PHE B 1 335 ? -1.328  -50.463 21.574  1.00 63.88  ? 335 PHE B C   1 
ATOM   6055  O O   . PHE B 1 335 ? -0.290  -50.292 22.227  1.00 58.02  ? 335 PHE B O   1 
ATOM   6056  C CB  . PHE B 1 335 ? -2.595  -48.462 20.762  1.00 74.20  ? 335 PHE B CB  1 
ATOM   6057  C CG  . PHE B 1 335 ? -1.931  -47.460 21.679  1.00 77.16  ? 335 PHE B CG  1 
ATOM   6058  C CD1 . PHE B 1 335 ? -1.077  -46.479 21.171  1.00 74.62  ? 335 PHE B CD1 1 
ATOM   6059  C CD2 . PHE B 1 335 ? -2.078  -47.566 23.059  1.00 69.24  ? 335 PHE B CD2 1 
ATOM   6060  C CE1 . PHE B 1 335 ? -0.426  -45.591 22.020  1.00 74.80  ? 335 PHE B CE1 1 
ATOM   6061  C CE2 . PHE B 1 335 ? -1.409  -46.693 23.908  1.00 76.96  ? 335 PHE B CE2 1 
ATOM   6062  C CZ  . PHE B 1 335 ? -0.593  -45.698 23.390  1.00 79.26  ? 335 PHE B CZ  1 
ATOM   6063  N N   . ALA B 1 336 ? -2.240  -51.386 21.898  1.00 67.58  ? 336 ALA B N   1 
ATOM   6064  C CA  . ALA B 1 336 ? -2.215  -52.102 23.169  1.00 71.78  ? 336 ALA B CA  1 
ATOM   6065  C C   . ALA B 1 336 ? -1.177  -53.228 23.148  1.00 80.21  ? 336 ALA B C   1 
ATOM   6066  O O   . ALA B 1 336 ? -0.538  -53.489 24.172  1.00 76.15  ? 336 ALA B O   1 
ATOM   6067  C CB  . ALA B 1 336 ? -3.601  -52.616 23.501  1.00 66.45  ? 336 ALA B CB  1 
ATOM   6068  N N   . LEU B 1 337 ? -1.019  -53.895 21.991  1.00 89.13  ? 337 LEU B N   1 
ATOM   6069  C CA  . LEU B 1 337 ? 0.051   -54.868 21.780  1.00 99.57  ? 337 LEU B CA  1 
ATOM   6070  C C   . LEU B 1 337 ? 1.415   -54.209 22.007  1.00 95.09  ? 337 LEU B C   1 
ATOM   6071  O O   . LEU B 1 337 ? 2.270   -54.752 22.708  1.00 90.41  ? 337 LEU B O   1 
ATOM   6072  C CB  . LEU B 1 337 ? -0.054  -55.448 20.360  1.00 100.99 ? 337 LEU B CB  1 
ATOM   6073  C CG  . LEU B 1 337 ? -1.178  -56.466 20.134  1.00 108.28 ? 337 LEU B CG  1 
ATOM   6074  C CD1 . LEU B 1 337 ? -1.446  -56.676 18.646  1.00 103.21 ? 337 LEU B CD1 1 
ATOM   6075  C CD2 . LEU B 1 337 ? -0.856  -57.797 20.807  1.00 107.76 ? 337 LEU B CD2 1 
ATOM   6076  N N   . LYS B 1 338 ? 1.599   -53.023 21.417  1.00 85.88  ? 338 LYS B N   1 
ATOM   6077  C CA  . LYS B 1 338 ? 2.843   -52.283 21.539  1.00 89.47  ? 338 LYS B CA  1 
ATOM   6078  C C   . LYS B 1 338 ? 3.122   -51.862 22.984  1.00 92.80  ? 338 LYS B C   1 
ATOM   6079  O O   . LYS B 1 338 ? 4.265   -51.967 23.425  1.00 91.64  ? 338 LYS B O   1 
ATOM   6080  C CB  . LYS B 1 338 ? 2.823   -51.045 20.635  1.00 102.10 ? 338 LYS B CB  1 
ATOM   6081  C CG  . LYS B 1 338 ? 3.226   -51.279 19.179  1.00 109.25 ? 338 LYS B CG  1 
ATOM   6082  C CD  . LYS B 1 338 ? 4.035   -50.126 18.609  1.00 120.44 ? 338 LYS B CD  1 
ATOM   6083  C CE  . LYS B 1 338 ? 5.389   -49.961 19.275  1.00 119.69 ? 338 LYS B CE  1 
ATOM   6084  N NZ  . LYS B 1 338 ? 5.619   -48.560 19.701  1.00 109.33 ? 338 LYS B NZ  1 
ATOM   6085  N N   . HIS B 1 339 ? 2.088   -51.400 23.714  1.00 93.16  ? 339 HIS B N   1 
ATOM   6086  C CA  . HIS B 1 339 ? 2.271   -50.536 24.877  1.00 82.44  ? 339 HIS B CA  1 
ATOM   6087  C C   . HIS B 1 339 ? 1.850   -51.166 26.205  1.00 79.33  ? 339 HIS B C   1 
ATOM   6088  O O   . HIS B 1 339 ? 2.212   -50.663 27.263  1.00 71.79  ? 339 HIS B O   1 
ATOM   6089  C CB  . HIS B 1 339 ? 1.498   -49.237 24.654  1.00 85.37  ? 339 HIS B CB  1 
ATOM   6090  C CG  . HIS B 1 339 ? 2.206   -48.266 23.765  1.00 83.62  ? 339 HIS B CG  1 
ATOM   6091  N ND1 . HIS B 1 339 ? 3.211   -47.429 24.204  1.00 75.68  ? 339 HIS B ND1 1 
ATOM   6092  C CD2 . HIS B 1 339 ? 2.039   -48.035 22.433  1.00 83.20  ? 339 HIS B CD2 1 
ATOM   6093  C CE1 . HIS B 1 339 ? 3.631   -46.684 23.184  1.00 77.51  ? 339 HIS B CE1 1 
ATOM   6094  N NE2 . HIS B 1 339 ? 2.914   -47.041 22.075  1.00 89.24  ? 339 HIS B NE2 1 
ATOM   6095  N N   . MET B 1 340 ? 1.064   -52.241 26.163  1.00 87.52  ? 340 MET B N   1 
ATOM   6096  C CA  . MET B 1 340 ? 0.579   -52.872 27.381  1.00 96.85  ? 340 MET B CA  1 
ATOM   6097  C C   . MET B 1 340 ? 0.242   -54.335 27.084  1.00 104.45 ? 340 MET B C   1 
ATOM   6098  O O   . MET B 1 340 ? -0.897  -54.765 27.287  1.00 92.96  ? 340 MET B O   1 
ATOM   6099  C CB  . MET B 1 340 ? -0.652  -52.132 27.932  1.00 98.01  ? 340 MET B CB  1 
ATOM   6100  C CG  . MET B 1 340 ? -1.483  -51.401 26.859  1.00 96.91  ? 340 MET B CG  1 
ATOM   6101  S SD  . MET B 1 340 ? -3.089  -50.691 27.400  1.00 88.50  ? 340 MET B SD  1 
ATOM   6102  C CE  . MET B 1 340 ? -3.951  -52.134 28.027  1.00 81.64  ? 340 MET B CE  1 
ATOM   6103  N N   . PRO B 1 341 ? 1.224   -55.138 26.591  1.00 109.65 ? 341 PRO B N   1 
ATOM   6104  C CA  . PRO B 1 341 ? 0.974   -56.544 26.258  1.00 103.47 ? 341 PRO B CA  1 
ATOM   6105  C C   . PRO B 1 341 ? 0.660   -57.373 27.510  1.00 106.60 ? 341 PRO B C   1 
ATOM   6106  O O   . PRO B 1 341 ? -0.152  -58.306 27.454  1.00 82.78  ? 341 PRO B O   1 
ATOM   6107  C CB  . PRO B 1 341 ? 2.271   -56.999 25.555  1.00 98.11  ? 341 PRO B CB  1 
ATOM   6108  C CG  . PRO B 1 341 ? 3.349   -56.049 26.065  1.00 95.09  ? 341 PRO B CG  1 
ATOM   6109  C CD  . PRO B 1 341 ? 2.630   -54.748 26.357  1.00 99.01  ? 341 PRO B CD  1 
ATOM   6110  N N   . ASP B 1 342 ? 1.251   -56.973 28.650  1.00 115.07 ? 342 ASP B N   1 
ATOM   6111  C CA  . ASP B 1 342 ? 1.212   -57.777 29.862  1.00 108.23 ? 342 ASP B CA  1 
ATOM   6112  C C   . ASP B 1 342 ? 0.107   -57.335 30.820  1.00 98.52  ? 342 ASP B C   1 
ATOM   6113  O O   . ASP B 1 342 ? -0.076  -58.001 31.834  1.00 96.80  ? 342 ASP B O   1 
ATOM   6114  C CB  . ASP B 1 342 ? 2.580   -57.820 30.554  1.00 107.45 ? 342 ASP B CB  1 
ATOM   6115  C CG  . ASP B 1 342 ? 3.648   -58.522 29.730  1.00 110.76 ? 342 ASP B CG  1 
ATOM   6116  O OD1 . ASP B 1 342 ? 3.308   -59.521 29.070  1.00 109.87 ? 342 ASP B OD1 1 
ATOM   6117  O OD2 . ASP B 1 342 ? 4.815   -58.084 29.773  1.00 108.34 ? 342 ASP B OD2 1 
ATOM   6118  N N   . ASP B 1 343 ? -0.646  -56.266 30.504  1.00 92.60  ? 343 ASP B N   1 
ATOM   6119  C CA  . ASP B 1 343 ? -1.771  -55.854 31.339  1.00 86.39  ? 343 ASP B CA  1 
ATOM   6120  C C   . ASP B 1 343 ? -2.792  -56.995 31.404  1.00 80.86  ? 343 ASP B C   1 
ATOM   6121  O O   . ASP B 1 343 ? -3.156  -57.551 30.362  1.00 64.94  ? 343 ASP B O   1 
ATOM   6122  C CB  . ASP B 1 343 ? -2.381  -54.530 30.848  1.00 90.58  ? 343 ASP B CB  1 
ATOM   6123  C CG  . ASP B 1 343 ? -3.680  -54.077 31.514  1.00 89.86  ? 343 ASP B CG  1 
ATOM   6124  O OD1 . ASP B 1 343 ? -4.753  -54.671 31.202  1.00 83.62  ? 343 ASP B OD1 1 
ATOM   6125  O OD2 . ASP B 1 343 ? -3.628  -53.093 32.309  1.00 81.82  ? 343 ASP B OD2 1 
ATOM   6126  N N   . PRO B 1 344 ? -3.267  -57.377 32.624  1.00 82.82  ? 344 PRO B N   1 
ATOM   6127  C CA  . PRO B 1 344 ? -4.251  -58.457 32.792  1.00 87.99  ? 344 PRO B CA  1 
ATOM   6128  C C   . PRO B 1 344 ? -5.551  -58.303 31.996  1.00 93.61  ? 344 PRO B C   1 
ATOM   6129  O O   . PRO B 1 344 ? -6.021  -59.270 31.389  1.00 93.28  ? 344 PRO B O   1 
ATOM   6130  C CB  . PRO B 1 344 ? -4.576  -58.430 34.299  1.00 85.39  ? 344 PRO B CB  1 
ATOM   6131  C CG  . PRO B 1 344 ? -3.351  -57.818 34.940  1.00 76.44  ? 344 PRO B CG  1 
ATOM   6132  C CD  . PRO B 1 344 ? -2.849  -56.815 33.922  1.00 78.11  ? 344 PRO B CD  1 
ATOM   6133  N N   . ILE B 1 345 ? -6.117  -57.082 32.000  1.00 95.30  ? 345 ILE B N   1 
ATOM   6134  C CA  . ILE B 1 345 ? -7.430  -56.809 31.417  1.00 83.45  ? 345 ILE B CA  1 
ATOM   6135  C C   . ILE B 1 345 ? -7.340  -56.801 29.884  1.00 73.23  ? 345 ILE B C   1 
ATOM   6136  O O   . ILE B 1 345 ? -8.256  -57.285 29.206  1.00 66.46  ? 345 ILE B O   1 
ATOM   6137  C CB  . ILE B 1 345 ? -8.042  -55.517 32.013  1.00 81.05  ? 345 ILE B CB  1 
ATOM   6138  C CG1 . ILE B 1 345 ? -8.157  -55.611 33.542  1.00 76.67  ? 345 ILE B CG1 1 
ATOM   6139  C CG2 . ILE B 1 345 ? -9.393  -55.201 31.377  1.00 79.49  ? 345 ILE B CG2 1 
ATOM   6140  C CD1 . ILE B 1 345 ? -8.806  -54.419 34.208  1.00 74.74  ? 345 ILE B CD1 1 
ATOM   6141  N N   . PHE B 1 346 ? -6.229  -56.283 29.335  1.00 68.37  ? 346 PHE B N   1 
ATOM   6142  C CA  . PHE B 1 346 ? -5.988  -56.402 27.902  1.00 67.89  ? 346 PHE B CA  1 
ATOM   6143  C C   . PHE B 1 346 ? -5.919  -57.871 27.462  1.00 69.93  ? 346 PHE B C   1 
ATOM   6144  O O   . PHE B 1 346 ? -6.487  -58.228 26.434  1.00 63.61  ? 346 PHE B O   1 
ATOM   6145  C CB  . PHE B 1 346 ? -4.711  -55.685 27.464  1.00 62.79  ? 346 PHE B CB  1 
ATOM   6146  C CG  . PHE B 1 346 ? -4.386  -55.926 26.011  1.00 69.02  ? 346 PHE B CG  1 
ATOM   6147  C CD1 . PHE B 1 346 ? -5.351  -55.746 25.024  1.00 72.89  ? 346 PHE B CD1 1 
ATOM   6148  C CD2 . PHE B 1 346 ? -3.131  -56.360 25.622  1.00 72.97  ? 346 PHE B CD2 1 
ATOM   6149  C CE1 . PHE B 1 346 ? -5.067  -55.999 23.687  1.00 71.16  ? 346 PHE B CE1 1 
ATOM   6150  C CE2 . PHE B 1 346 ? -2.848  -56.595 24.281  1.00 77.65  ? 346 PHE B CE2 1 
ATOM   6151  C CZ  . PHE B 1 346 ? -3.816  -56.420 23.313  1.00 72.43  ? 346 PHE B CZ  1 
ATOM   6152  N N   . GLN B 1 347 ? -5.220  -58.716 28.235  1.00 70.46  ? 347 GLN B N   1 
ATOM   6153  C CA  . GLN B 1 347 ? -5.067  -60.126 27.906  1.00 74.05  ? 347 GLN B CA  1 
ATOM   6154  C C   . GLN B 1 347 ? -6.416  -60.833 27.819  1.00 75.41  ? 347 GLN B C   1 
ATOM   6155  O O   . GLN B 1 347 ? -6.542  -61.801 27.064  1.00 72.49  ? 347 GLN B O   1 
ATOM   6156  C CB  . GLN B 1 347 ? -4.196  -60.857 28.933  1.00 78.36  ? 347 GLN B CB  1 
ATOM   6157  C CG  . GLN B 1 347 ? -2.705  -60.633 28.717  1.00 79.37  ? 347 GLN B CG  1 
ATOM   6158  C CD  . GLN B 1 347 ? -1.868  -61.189 29.842  1.00 80.51  ? 347 GLN B CD  1 
ATOM   6159  O OE1 . GLN B 1 347 ? -0.710  -60.822 29.998  1.00 86.97  ? 347 GLN B OE1 1 
ATOM   6160  N NE2 . GLN B 1 347 ? -2.457  -62.034 30.675  1.00 82.58  ? 347 GLN B NE2 1 
ATOM   6161  N N   . VAL B 1 348 ? -7.407  -60.360 28.588  1.00 72.07  ? 348 VAL B N   1 
ATOM   6162  C CA  . VAL B 1 348 ? -8.751  -60.929 28.541  1.00 74.55  ? 348 VAL B CA  1 
ATOM   6163  C C   . VAL B 1 348 ? -9.546  -60.427 27.334  1.00 78.19  ? 348 VAL B C   1 
ATOM   6164  O O   . VAL B 1 348 ? -10.338 -61.174 26.762  1.00 80.72  ? 348 VAL B O   1 
ATOM   6165  C CB  . VAL B 1 348 ? -9.494  -60.660 29.856  1.00 67.89  ? 348 VAL B CB  1 
ATOM   6166  C CG1 . VAL B 1 348 ? -10.994 -60.878 29.729  1.00 70.96  ? 348 VAL B CG1 1 
ATOM   6167  C CG2 . VAL B 1 348 ? -8.897  -61.521 30.950  1.00 61.28  ? 348 VAL B CG2 1 
ATOM   6168  N N   . VAL B 1 349 ? -9.359  -59.155 26.974  1.00 92.74  ? 349 VAL B N   1 
ATOM   6169  C CA  . VAL B 1 349 ? -9.891  -58.615 25.732  1.00 96.92  ? 349 VAL B CA  1 
ATOM   6170  C C   . VAL B 1 349 ? -9.283  -59.351 24.538  1.00 88.22  ? 349 VAL B C   1 
ATOM   6171  O O   . VAL B 1 349 ? -9.997  -59.644 23.587  1.00 86.74  ? 349 VAL B O   1 
ATOM   6172  C CB  . VAL B 1 349 ? -9.618  -57.101 25.638  1.00 108.66 ? 349 VAL B CB  1 
ATOM   6173  C CG1 . VAL B 1 349 ? -9.723  -56.570 24.209  1.00 113.14 ? 349 VAL B CG1 1 
ATOM   6174  C CG2 . VAL B 1 349 ? -10.528 -56.328 26.580  1.00 117.88 ? 349 VAL B CG2 1 
ATOM   6175  N N   . SER B 1 350 ? -7.964  -59.600 24.602  1.00 82.48  ? 350 SER B N   1 
ATOM   6176  C CA  . SER B 1 350 ? -7.173  -60.205 23.536  1.00 84.68  ? 350 SER B CA  1 
ATOM   6177  C C   . SER B 1 350 ? -7.691  -61.600 23.181  1.00 86.44  ? 350 SER B C   1 
ATOM   6178  O O   . SER B 1 350 ? -7.941  -61.914 22.007  1.00 72.49  ? 350 SER B O   1 
ATOM   6179  C CB  . SER B 1 350 ? -5.725  -60.259 23.950  1.00 75.29  ? 350 SER B CB  1 
ATOM   6180  O OG  . SER B 1 350 ? -4.906  -60.599 22.848  1.00 79.23  ? 350 SER B OG  1 
ATOM   6181  N N   . MET B 1 351 ? -7.839  -62.424 24.230  1.00 88.78  ? 351 MET B N   1 
ATOM   6182  C CA  . MET B 1 351 ? -8.419  -63.754 24.129  1.00 95.32  ? 351 MET B CA  1 
ATOM   6183  C C   . MET B 1 351 ? -9.865  -63.693 23.632  1.00 91.37  ? 351 MET B C   1 
ATOM   6184  O O   . MET B 1 351 ? -10.240 -64.509 22.791  1.00 121.99 ? 351 MET B O   1 
ATOM   6185  C CB  . MET B 1 351 ? -8.376  -64.479 25.478  1.00 97.36  ? 351 MET B CB  1 
ATOM   6186  C CG  . MET B 1 351 ? -7.115  -65.304 25.691  1.00 99.22  ? 351 MET B CG  1 
ATOM   6187  S SD  . MET B 1 351 ? -6.818  -65.696 27.440  1.00 106.64 ? 351 MET B SD  1 
ATOM   6188  C CE  . MET B 1 351 ? -8.285  -66.657 27.811  1.00 98.58  ? 351 MET B CE  1 
ATOM   6189  N N   . LEU B 1 352 ? -10.677 -62.758 24.150  1.00 85.76  ? 352 LEU B N   1 
ATOM   6190  C CA  . LEU B 1 352 ? -12.072 -62.643 23.731  1.00 89.84  ? 352 LEU B CA  1 
ATOM   6191  C C   . LEU B 1 352 ? -12.191 -62.439 22.217  1.00 91.55  ? 352 LEU B C   1 
ATOM   6192  O O   . LEU B 1 352 ? -13.142 -62.932 21.611  1.00 78.02  ? 352 LEU B O   1 
ATOM   6193  C CB  . LEU B 1 352 ? -12.756 -61.483 24.463  1.00 91.79  ? 352 LEU B CB  1 
ATOM   6194  C CG  . LEU B 1 352 ? -13.257 -61.774 25.876  1.00 93.13  ? 352 LEU B CG  1 
ATOM   6195  C CD1 . LEU B 1 352 ? -13.780 -60.509 26.539  1.00 93.41  ? 352 LEU B CD1 1 
ATOM   6196  C CD2 . LEU B 1 352 ? -14.343 -62.832 25.871  1.00 103.76 ? 352 LEU B CD2 1 
ATOM   6197  N N   . TYR B 1 353 ? -11.258 -61.671 21.628  1.00 97.14  ? 353 TYR B N   1 
ATOM   6198  C CA  . TYR B 1 353 ? -11.206 -61.438 20.188  1.00 94.67  ? 353 TYR B CA  1 
ATOM   6199  C C   . TYR B 1 353 ? -11.173 -62.772 19.435  1.00 94.10  ? 353 TYR B C   1 
ATOM   6200  O O   . TYR B 1 353 ? -11.829 -62.929 18.406  1.00 86.00  ? 353 TYR B O   1 
ATOM   6201  C CB  . TYR B 1 353 ? -9.957  -60.624 19.813  1.00 87.31  ? 353 TYR B CB  1 
ATOM   6202  C CG  . TYR B 1 353 ? -9.912  -60.095 18.397  1.00 90.45  ? 353 TYR B CG  1 
ATOM   6203  C CD1 . TYR B 1 353 ? -11.079 -59.854 17.674  1.00 94.11  ? 353 TYR B CD1 1 
ATOM   6204  C CD2 . TYR B 1 353 ? -8.697  -59.863 17.755  1.00 88.88  ? 353 TYR B CD2 1 
ATOM   6205  C CE1 . TYR B 1 353 ? -11.041 -59.366 16.372  1.00 95.74  ? 353 TYR B CE1 1 
ATOM   6206  C CE2 . TYR B 1 353 ? -8.641  -59.384 16.448  1.00 88.03  ? 353 TYR B CE2 1 
ATOM   6207  C CZ  . TYR B 1 353 ? -9.818  -59.127 15.754  1.00 95.03  ? 353 TYR B CZ  1 
ATOM   6208  O OH  . TYR B 1 353 ? -9.806  -58.628 14.467  1.00 78.11  ? 353 TYR B OH  1 
ATOM   6209  N N   . GLU B 1 354 ? -10.396 -63.730 19.962  1.00 98.45  ? 354 GLU B N   1 
ATOM   6210  C CA  . GLU B 1 354 ? -10.181 -65.019 19.319  1.00 97.11  ? 354 GLU B CA  1 
ATOM   6211  C C   . GLU B 1 354 ? -11.430 -65.890 19.460  1.00 94.07  ? 354 GLU B C   1 
ATOM   6212  O O   . GLU B 1 354 ? -11.944 -66.419 18.472  1.00 82.27  ? 354 GLU B O   1 
ATOM   6213  C CB  . GLU B 1 354 ? -8.960  -65.700 19.941  1.00 97.81  ? 354 GLU B CB  1 
ATOM   6214  C CG  . GLU B 1 354 ? -8.043  -66.331 18.909  1.00 110.47 ? 354 GLU B CG  1 
ATOM   6215  C CD  . GLU B 1 354 ? -6.591  -66.415 19.352  1.00 127.44 ? 354 GLU B CD  1 
ATOM   6216  O OE1 . GLU B 1 354 ? -6.078  -67.546 19.460  1.00 147.83 ? 354 GLU B OE1 1 
ATOM   6217  O OE2 . GLU B 1 354 ? -5.973  -65.350 19.596  1.00 126.72 ? 354 GLU B OE2 1 
ATOM   6218  N N   . VAL B 1 355 ? -11.940 -65.972 20.694  1.00 95.50  ? 355 VAL B N   1 
ATOM   6219  C CA  . VAL B 1 355 ? -12.858 -67.021 21.091  1.00 101.16 ? 355 VAL B CA  1 
ATOM   6220  C C   . VAL B 1 355 ? -14.319 -66.619 20.828  1.00 106.08 ? 355 VAL B C   1 
ATOM   6221  O O   . VAL B 1 355 ? -15.148 -67.498 20.591  1.00 117.99 ? 355 VAL B O   1 
ATOM   6222  C CB  . VAL B 1 355 ? -12.595 -67.414 22.564  1.00 106.55 ? 355 VAL B CB  1 
ATOM   6223  C CG1 . VAL B 1 355 ? -13.495 -66.660 23.537  1.00 108.35 ? 355 VAL B CG1 1 
ATOM   6224  C CG2 . VAL B 1 355 ? -12.712 -68.919 22.799  1.00 108.92 ? 355 VAL B CG2 1 
ATOM   6225  N N   . VAL B 1 356 ? -14.651 -65.315 20.847  1.00 101.52 ? 356 VAL B N   1 
ATOM   6226  C CA  . VAL B 1 356 ? -16.047 -64.878 20.859  1.00 94.55  ? 356 VAL B CA  1 
ATOM   6227  C C   . VAL B 1 356 ? -16.671 -64.887 19.457  1.00 91.07  ? 356 VAL B C   1 
ATOM   6228  O O   . VAL B 1 356 ? -17.863 -65.173 19.331  1.00 77.33  ? 356 VAL B O   1 
ATOM   6229  C CB  . VAL B 1 356 ? -16.228 -63.494 21.522  1.00 90.02  ? 356 VAL B CB  1 
ATOM   6230  C CG1 . VAL B 1 356 ? -17.695 -63.085 21.573  1.00 92.27  ? 356 VAL B CG1 1 
ATOM   6231  C CG2 . VAL B 1 356 ? -15.631 -63.439 22.921  1.00 89.30  ? 356 VAL B CG2 1 
ATOM   6232  N N   . PRO B 1 357 ? -15.961 -64.494 18.370  1.00 101.45 ? 357 PRO B N   1 
ATOM   6233  C CA  . PRO B 1 357 ? -16.530 -64.579 17.019  1.00 108.95 ? 357 PRO B CA  1 
ATOM   6234  C C   . PRO B 1 357 ? -16.851 -65.990 16.505  1.00 122.80 ? 357 PRO B C   1 
ATOM   6235  O O   . PRO B 1 357 ? -17.920 -66.156 15.925  1.00 128.85 ? 357 PRO B O   1 
ATOM   6236  C CB  . PRO B 1 357 ? -15.496 -63.873 16.128  1.00 108.83 ? 357 PRO B CB  1 
ATOM   6237  C CG  . PRO B 1 357 ? -14.688 -63.020 17.084  1.00 101.96 ? 357 PRO B CG  1 
ATOM   6238  C CD  . PRO B 1 357 ? -14.654 -63.818 18.372  1.00 99.31  ? 357 PRO B CD  1 
ATOM   6239  N N   . PRO B 1 358 ? -15.989 -67.041 16.656  1.00 129.57 ? 358 PRO B N   1 
ATOM   6240  C CA  . PRO B 1 358 ? -16.415 -68.430 16.408  1.00 108.49 ? 358 PRO B CA  1 
ATOM   6241  C C   . PRO B 1 358 ? -17.756 -68.833 17.038  1.00 97.89  ? 358 PRO B C   1 
ATOM   6242  O O   . PRO B 1 358 ? -18.554 -69.509 16.398  1.00 88.37  ? 358 PRO B O   1 
ATOM   6243  C CB  . PRO B 1 358 ? -15.245 -69.250 16.991  1.00 99.44  ? 358 PRO B CB  1 
ATOM   6244  C CG  . PRO B 1 358 ? -14.031 -68.378 16.747  1.00 101.09 ? 358 PRO B CG  1 
ATOM   6245  C CD  . PRO B 1 358 ? -14.548 -66.969 16.980  1.00 120.16 ? 358 PRO B CD  1 
ATOM   6246  N N   . ILE B 1 359 ? -18.025 -68.354 18.265  1.00 107.36 ? 359 ILE B N   1 
ATOM   6247  C CA  . ILE B 1 359 ? -19.155 -68.783 19.087  1.00 105.94 ? 359 ILE B CA  1 
ATOM   6248  C C   . ILE B 1 359 ? -20.451 -68.031 18.739  1.00 110.25 ? 359 ILE B C   1 
ATOM   6249  O O   . ILE B 1 359 ? -21.536 -68.621 18.766  1.00 109.54 ? 359 ILE B O   1 
ATOM   6250  C CB  . ILE B 1 359 ? -18.785 -68.650 20.580  1.00 94.88  ? 359 ILE B CB  1 
ATOM   6251  C CG1 . ILE B 1 359 ? -17.621 -69.579 20.938  1.00 94.94  ? 359 ILE B CG1 1 
ATOM   6252  C CG2 . ILE B 1 359 ? -19.991 -68.914 21.465  1.00 101.83 ? 359 ILE B CG2 1 
ATOM   6253  C CD1 . ILE B 1 359 ? -17.097 -69.440 22.350  1.00 95.69  ? 359 ILE B CD1 1 
ATOM   6254  N N   . LEU B 1 360 ? -20.359 -66.726 18.442  1.00 111.96 ? 360 LEU B N   1 
ATOM   6255  C CA  . LEU B 1 360 ? -21.509 -65.953 17.987  1.00 110.88 ? 360 LEU B CA  1 
ATOM   6256  C C   . LEU B 1 360 ? -21.836 -66.310 16.530  1.00 115.26 ? 360 LEU B C   1 
ATOM   6257  O O   . LEU B 1 360 ? -22.866 -65.898 15.997  1.00 107.65 ? 360 LEU B O   1 
ATOM   6258  C CB  . LEU B 1 360 ? -21.199 -64.453 18.142  1.00 117.04 ? 360 LEU B CB  1 
ATOM   6259  C CG  . LEU B 1 360 ? -21.013 -63.920 19.568  1.00 110.03 ? 360 LEU B CG  1 
ATOM   6260  C CD1 . LEU B 1 360 ? -20.353 -62.549 19.550  1.00 106.46 ? 360 LEU B CD1 1 
ATOM   6261  C CD2 . LEU B 1 360 ? -22.339 -63.833 20.311  1.00 107.88 ? 360 LEU B CD2 1 
ATOM   6262  N N   . SER B 1 361 ? -20.944 -67.083 15.891  1.00 124.46 ? 361 SER B N   1 
ATOM   6263  C CA  . SER B 1 361 ? -21.094 -67.530 14.514  1.00 123.84 ? 361 SER B CA  1 
ATOM   6264  C C   . SER B 1 361 ? -21.944 -68.806 14.437  1.00 125.48 ? 361 SER B C   1 
ATOM   6265  O O   . SER B 1 361 ? -22.824 -68.907 13.577  1.00 97.92  ? 361 SER B O   1 
ATOM   6266  C CB  . SER B 1 361 ? -19.732 -67.735 13.900  1.00 116.11 ? 361 SER B CB  1 
ATOM   6267  O OG  . SER B 1 361 ? -19.696 -67.185 12.598  1.00 115.61 ? 361 SER B OG  1 
ATOM   6268  N N   . SER B 1 362 ? -21.660 -69.769 15.338  1.00 126.88 ? 362 SER B N   1 
ATOM   6269  C CA  . SER B 1 362 ? -22.459 -70.974 15.545  1.00 127.71 ? 362 SER B CA  1 
ATOM   6270  C C   . SER B 1 362 ? -23.949 -70.654 15.648  1.00 138.85 ? 362 SER B C   1 
ATOM   6271  O O   . SER B 1 362 ? -24.775 -71.391 15.110  1.00 151.78 ? 362 SER B O   1 
ATOM   6272  C CB  . SER B 1 362 ? -22.042 -71.718 16.801  1.00 119.44 ? 362 SER B CB  1 
ATOM   6273  O OG  . SER B 1 362 ? -20.708 -72.178 16.733  1.00 119.37 ? 362 SER B OG  1 
ATOM   6274  N N   . LEU B 1 363 ? -24.282 -69.587 16.390  1.00 135.11 ? 363 LEU B N   1 
ATOM   6275  C CA  . LEU B 1 363 ? -25.666 -69.254 16.696  1.00 130.31 ? 363 LEU B CA  1 
ATOM   6276  C C   . LEU B 1 363 ? -26.319 -68.499 15.528  1.00 130.18 ? 363 LEU B C   1 
ATOM   6277  O O   . LEU B 1 363 ? -27.543 -68.423 15.472  1.00 132.12 ? 363 LEU B O   1 
ATOM   6278  C CB  . LEU B 1 363 ? -25.720 -68.434 17.995  1.00 130.07 ? 363 LEU B CB  1 
ATOM   6279  C CG  . LEU B 1 363 ? -24.955 -68.972 19.209  1.00 128.24 ? 363 LEU B CG  1 
ATOM   6280  C CD1 . LEU B 1 363 ? -25.481 -68.346 20.496  1.00 128.11 ? 363 LEU B CD1 1 
ATOM   6281  C CD2 . LEU B 1 363 ? -25.018 -70.488 19.310  1.00 121.45 ? 363 LEU B CD2 1 
ATOM   6282  N N   . GLY B 1 364 ? -25.516 -67.934 14.608  1.00 131.00 ? 364 GLY B N   1 
ATOM   6283  C CA  . GLY B 1 364 ? -26.003 -67.213 13.435  1.00 127.01 ? 364 GLY B CA  1 
ATOM   6284  C C   . GLY B 1 364 ? -27.142 -66.243 13.759  1.00 129.22 ? 364 GLY B C   1 
ATOM   6285  O O   . GLY B 1 364 ? -28.038 -66.037 12.942  1.00 110.62 ? 364 GLY B O   1 
ATOM   6286  N N   . LYS B 1 365 ? -27.043 -65.611 14.937  1.00 141.85 ? 365 LYS B N   1 
ATOM   6287  C CA  . LYS B 1 365 ? -28.153 -64.997 15.658  1.00 137.24 ? 365 LYS B CA  1 
ATOM   6288  C C   . LYS B 1 365 ? -28.131 -63.476 15.461  1.00 138.84 ? 365 LYS B C   1 
ATOM   6289  O O   . LYS B 1 365 ? -29.061 -62.906 14.894  1.00 118.90 ? 365 LYS B O   1 
ATOM   6290  C CB  . LYS B 1 365 ? -27.994 -65.375 17.136  1.00 124.16 ? 365 LYS B CB  1 
ATOM   6291  C CG  . LYS B 1 365 ? -29.104 -64.961 18.093  1.00 117.86 ? 365 LYS B CG  1 
ATOM   6292  C CD  . LYS B 1 365 ? -29.829 -66.119 18.726  1.00 117.00 ? 365 LYS B CD  1 
ATOM   6293  C CE  . LYS B 1 365 ? -30.456 -65.713 20.048  1.00 112.82 ? 365 LYS B CE  1 
ATOM   6294  N NZ  . LYS B 1 365 ? -31.276 -66.804 20.630  1.00 113.04 ? 365 LYS B NZ  1 
ATOM   6295  N N   . VAL B 1 366 ? -27.045 -62.843 15.938  1.00 143.06 ? 366 VAL B N   1 
ATOM   6296  C CA  . VAL B 1 366 ? -26.833 -61.402 15.886  1.00 131.94 ? 366 VAL B CA  1 
ATOM   6297  C C   . VAL B 1 366 ? -26.163 -61.061 14.551  1.00 125.69 ? 366 VAL B C   1 
ATOM   6298  O O   . VAL B 1 366 ? -25.287 -61.790 14.086  1.00 119.33 ? 366 VAL B O   1 
ATOM   6299  C CB  . VAL B 1 366 ? -26.000 -60.911 17.097  1.00 119.97 ? 366 VAL B CB  1 
ATOM   6300  C CG1 . VAL B 1 366 ? -26.675 -61.240 18.425  1.00 114.57 ? 366 VAL B CG1 1 
ATOM   6301  C CG2 . VAL B 1 366 ? -24.571 -61.446 17.087  1.00 102.79 ? 366 VAL B CG2 1 
ATOM   6302  N N   . LYS B 1 367 ? -26.563 -59.931 13.953  1.00 115.21 ? 367 LYS B N   1 
ATOM   6303  C CA  . LYS B 1 367 ? -26.184 -59.597 12.586  1.00 108.41 ? 367 LYS B CA  1 
ATOM   6304  C C   . LYS B 1 367 ? -24.717 -59.138 12.482  1.00 110.03 ? 367 LYS B C   1 
ATOM   6305  O O   . LYS B 1 367 ? -24.223 -58.973 11.366  1.00 101.67 ? 367 LYS B O   1 
ATOM   6306  C CB  . LYS B 1 367 ? -27.179 -58.569 12.028  1.00 93.76  ? 367 LYS B CB  1 
ATOM   6307  N N   . ASP B 1 368 ? -24.015 -58.936 13.619  1.00 122.66 ? 368 ASP B N   1 
ATOM   6308  C CA  . ASP B 1 368 ? -22.591 -58.584 13.650  1.00 116.38 ? 368 ASP B CA  1 
ATOM   6309  C C   . ASP B 1 368 ? -21.884 -59.448 14.698  1.00 113.44 ? 368 ASP B C   1 
ATOM   6310  O O   . ASP B 1 368 ? -21.870 -59.099 15.878  1.00 109.55 ? 368 ASP B O   1 
ATOM   6311  C CB  . ASP B 1 368 ? -22.376 -57.082 13.922  1.00 109.49 ? 368 ASP B CB  1 
ATOM   6312  C CG  . ASP B 1 368 ? -20.936 -56.577 14.024  1.00 99.41  ? 368 ASP B CG  1 
ATOM   6313  O OD1 . ASP B 1 368 ? -20.073 -57.125 13.320  1.00 100.88 ? 368 ASP B OD1 1 
ATOM   6314  O OD2 . ASP B 1 368 ? -20.692 -55.593 14.773  1.00 81.13  ? 368 ASP B OD2 1 
ATOM   6315  N N   . PRO B 1 369 ? -21.273 -60.598 14.312  1.00 119.35 ? 369 PRO B N   1 
ATOM   6316  C CA  . PRO B 1 369 ? -20.625 -61.506 15.271  1.00 114.50 ? 369 PRO B CA  1 
ATOM   6317  C C   . PRO B 1 369 ? -19.196 -61.126 15.666  1.00 108.02 ? 369 PRO B C   1 
ATOM   6318  O O   . PRO B 1 369 ? -18.353 -61.997 15.913  1.00 93.95  ? 369 PRO B O   1 
ATOM   6319  C CB  . PRO B 1 369 ? -20.628 -62.836 14.496  1.00 113.89 ? 369 PRO B CB  1 
ATOM   6320  C CG  . PRO B 1 369 ? -20.478 -62.425 13.044  1.00 115.49 ? 369 PRO B CG  1 
ATOM   6321  C CD  . PRO B 1 369 ? -21.204 -61.100 12.926  1.00 116.49 ? 369 PRO B CD  1 
ATOM   6322  N N   . TRP B 1 370 ? -18.950 -59.812 15.764  1.00 108.59 ? 370 TRP B N   1 
ATOM   6323  C CA  . TRP B 1 370 ? -17.605 -59.256 15.780  1.00 109.58 ? 370 TRP B CA  1 
ATOM   6324  C C   . TRP B 1 370 ? -17.557 -58.066 16.737  1.00 96.32  ? 370 TRP B C   1 
ATOM   6325  O O   . TRP B 1 370 ? -18.606 -57.555 17.132  1.00 91.10  ? 370 TRP B O   1 
ATOM   6326  C CB  . TRP B 1 370 ? -17.181 -58.866 14.352  1.00 110.11 ? 370 TRP B CB  1 
ATOM   6327  C CG  . TRP B 1 370 ? -16.944 -60.030 13.435  1.00 105.67 ? 370 TRP B CG  1 
ATOM   6328  C CD1 . TRP B 1 370 ? -17.786 -60.490 12.463  1.00 101.81 ? 370 TRP B CD1 1 
ATOM   6329  C CD2 . TRP B 1 370 ? -15.773 -60.867 13.379  1.00 108.04 ? 370 TRP B CD2 1 
ATOM   6330  N NE1 . TRP B 1 370 ? -17.234 -61.570 11.828  1.00 100.99 ? 370 TRP B NE1 1 
ATOM   6331  C CE2 . TRP B 1 370 ? -16.001 -61.824 12.366  1.00 105.64 ? 370 TRP B CE2 1 
ATOM   6332  C CE3 . TRP B 1 370 ? -14.562 -60.909 14.087  1.00 116.84 ? 370 TRP B CE3 1 
ATOM   6333  C CZ2 . TRP B 1 370 ? -15.058 -62.802 12.046  1.00 109.34 ? 370 TRP B CZ2 1 
ATOM   6334  C CZ3 . TRP B 1 370 ? -13.627 -61.871 13.765  1.00 111.64 ? 370 TRP B CZ3 1 
ATOM   6335  C CH2 . TRP B 1 370 ? -13.876 -62.804 12.757  1.00 111.61 ? 370 TRP B CH2 1 
ATOM   6336  N N   . PRO B 1 371 ? -16.347 -57.614 17.150  1.00 92.84  ? 371 PRO B N   1 
ATOM   6337  C CA  . PRO B 1 371 ? -16.204 -56.451 18.034  1.00 95.80  ? 371 PRO B CA  1 
ATOM   6338  C C   . PRO B 1 371 ? -16.360 -55.075 17.385  1.00 90.09  ? 371 PRO B C   1 
ATOM   6339  O O   . PRO B 1 371 ? -16.047 -54.917 16.199  1.00 73.50  ? 371 PRO B O   1 
ATOM   6340  C CB  . PRO B 1 371 ? -14.762 -56.589 18.567  1.00 101.95 ? 371 PRO B CB  1 
ATOM   6341  C CG  . PRO B 1 371 ? -14.017 -57.334 17.478  1.00 102.09 ? 371 PRO B CG  1 
ATOM   6342  C CD  . PRO B 1 371 ? -15.051 -58.254 16.857  1.00 98.39  ? 371 PRO B CD  1 
ATOM   6343  N N   . ASN B 1 372 ? -16.850 -54.109 18.197  1.00 94.95  ? 372 ASN B N   1 
ATOM   6344  C CA  . ASN B 1 372 ? -16.771 -52.671 17.921  1.00 88.67  ? 372 ASN B CA  1 
ATOM   6345  C C   . ASN B 1 372 ? -15.748 -52.032 18.878  1.00 86.59  ? 372 ASN B C   1 
ATOM   6346  O O   . ASN B 1 372 ? -15.096 -52.743 19.645  1.00 84.86  ? 372 ASN B O   1 
ATOM   6347  C CB  . ASN B 1 372 ? -18.166 -52.020 17.886  1.00 84.17  ? 372 ASN B CB  1 
ATOM   6348  C CG  . ASN B 1 372 ? -18.934 -52.064 19.194  1.00 86.82  ? 372 ASN B CG  1 
ATOM   6349  O OD1 . ASN B 1 372 ? -18.673 -51.270 20.100  1.00 99.08  ? 372 ASN B OD1 1 
ATOM   6350  N ND2 . ASN B 1 372 ? -19.915 -52.952 19.287  1.00 78.27  ? 372 ASN B ND2 1 
ATOM   6351  N N   . VAL B 1 373 ? -15.564 -50.699 18.807  1.00 85.66  ? 373 VAL B N   1 
ATOM   6352  C CA  . VAL B 1 373 ? -14.512 -50.004 19.554  1.00 75.52  ? 373 VAL B CA  1 
ATOM   6353  C C   . VAL B 1 373 ? -14.638 -50.197 21.059  1.00 73.97  ? 373 VAL B C   1 
ATOM   6354  O O   . VAL B 1 373 ? -13.620 -50.285 21.736  1.00 73.44  ? 373 VAL B O   1 
ATOM   6355  C CB  . VAL B 1 373 ? -14.464 -48.488 19.306  1.00 74.67  ? 373 VAL B CB  1 
ATOM   6356  C CG1 . VAL B 1 373 ? -13.129 -48.083 18.722  1.00 84.24  ? 373 VAL B CG1 1 
ATOM   6357  C CG2 . VAL B 1 373 ? -15.626 -47.956 18.482  1.00 78.23  ? 373 VAL B CG2 1 
ATOM   6358  N N   . ASP B 1 374 ? -15.879 -50.177 21.562  1.00 75.12  ? 374 ASP B N   1 
ATOM   6359  C CA  . ASP B 1 374 ? -16.170 -50.131 22.989  1.00 77.58  ? 374 ASP B CA  1 
ATOM   6360  C C   . ASP B 1 374 ? -15.626 -51.365 23.713  1.00 74.99  ? 374 ASP B C   1 
ATOM   6361  O O   . ASP B 1 374 ? -15.377 -51.329 24.923  1.00 66.20  ? 374 ASP B O   1 
ATOM   6362  C CB  . ASP B 1 374 ? -17.674 -49.963 23.208  1.00 90.82  ? 374 ASP B CB  1 
ATOM   6363  C CG  . ASP B 1 374 ? -18.235 -48.729 22.519  1.00 98.28  ? 374 ASP B CG  1 
ATOM   6364  O OD1 . ASP B 1 374 ? -17.695 -47.638 22.761  1.00 108.66 ? 374 ASP B OD1 1 
ATOM   6365  O OD2 . ASP B 1 374 ? -19.210 -48.869 21.748  1.00 103.66 ? 374 ASP B OD2 1 
ATOM   6366  N N   . ALA B 1 375 ? -15.395 -52.439 22.947  1.00 77.74  ? 375 ALA B N   1 
ATOM   6367  C CA  . ALA B 1 375 ? -14.728 -53.633 23.446  1.00 70.02  ? 375 ALA B CA  1 
ATOM   6368  C C   . ALA B 1 375 ? -13.283 -53.355 23.886  1.00 72.60  ? 375 ALA B C   1 
ATOM   6369  O O   . ALA B 1 375 ? -12.763 -54.069 24.745  1.00 78.54  ? 375 ALA B O   1 
ATOM   6370  C CB  . ALA B 1 375 ? -14.791 -54.712 22.393  1.00 62.71  ? 375 ALA B CB  1 
ATOM   6371  N N   . HIS B 1 376 ? -12.630 -52.322 23.326  1.00 73.56  ? 376 HIS B N   1 
ATOM   6372  C CA  . HIS B 1 376 ? -11.193 -52.144 23.508  1.00 69.21  ? 376 HIS B CA  1 
ATOM   6373  C C   . HIS B 1 376 ? -10.808 -50.804 24.151  1.00 67.00  ? 376 HIS B C   1 
ATOM   6374  O O   . HIS B 1 376 ? -9.661  -50.633 24.555  1.00 69.30  ? 376 HIS B O   1 
ATOM   6375  C CB  . HIS B 1 376 ? -10.491 -52.303 22.152  1.00 68.87  ? 376 HIS B CB  1 
ATOM   6376  C CG  . HIS B 1 376 ? -9.159  -52.979 22.237  1.00 73.68  ? 376 HIS B CG  1 
ATOM   6377  N ND1 . HIS B 1 376 ? -8.184  -52.628 23.140  1.00 81.48  ? 376 HIS B ND1 1 
ATOM   6378  C CD2 . HIS B 1 376 ? -8.681  -54.035 21.523  1.00 83.23  ? 376 HIS B CD2 1 
ATOM   6379  C CE1 . HIS B 1 376 ? -7.132  -53.424 22.978  1.00 89.71  ? 376 HIS B CE1 1 
ATOM   6380  N NE2 . HIS B 1 376 ? -7.424  -54.316 21.981  1.00 101.91 ? 376 HIS B NE2 1 
ATOM   6381  N N   . SER B 1 377 ? -11.736 -49.843 24.253  1.00 71.00  ? 377 SER B N   1 
ATOM   6382  C CA  . SER B 1 377 ? -11.400 -48.483 24.678  1.00 66.87  ? 377 SER B CA  1 
ATOM   6383  C C   . SER B 1 377 ? -11.022 -48.433 26.164  1.00 62.73  ? 377 SER B C   1 
ATOM   6384  O O   . SER B 1 377 ? -9.994  -47.861 26.534  1.00 51.08  ? 377 SER B O   1 
ATOM   6385  C CB  . SER B 1 377 ? -12.542 -47.522 24.387  1.00 64.97  ? 377 SER B CB  1 
ATOM   6386  O OG  . SER B 1 377 ? -12.736 -47.342 22.985  1.00 80.03  ? 377 SER B OG  1 
ATOM   6387  N N   . GLY B 1 378 ? -11.881 -49.042 26.997  1.00 60.06  ? 378 GLY B N   1 
ATOM   6388  C CA  . GLY B 1 378 ? -11.874 -48.857 28.435  1.00 59.95  ? 378 GLY B CA  1 
ATOM   6389  C C   . GLY B 1 378 ? -10.625 -49.421 29.095  1.00 61.11  ? 378 GLY B C   1 
ATOM   6390  O O   . GLY B 1 378 ? -10.119 -48.846 30.064  1.00 53.28  ? 378 GLY B O   1 
ATOM   6391  N N   . CYS B 1 379 ? -10.134 -50.541 28.557  1.00 64.48  ? 379 CYS B N   1 
ATOM   6392  C CA  . CYS B 1 379 ? -9.001  -51.219 29.166  1.00 68.77  ? 379 CYS B CA  1 
ATOM   6393  C C   . CYS B 1 379 ? -7.736  -50.360 29.033  1.00 65.08  ? 379 CYS B C   1 
ATOM   6394  O O   . CYS B 1 379 ? -6.860  -50.398 29.902  1.00 59.62  ? 379 CYS B O   1 
ATOM   6395  C CB  . CYS B 1 379 ? -8.832  -52.638 28.615  1.00 76.86  ? 379 CYS B CB  1 
ATOM   6396  S SG  . CYS B 1 379 ? -8.280  -52.749 26.890  1.00 80.04  ? 379 CYS B SG  1 
ATOM   6397  N N   . ILE B 1 380 ? -7.669  -49.539 27.979  1.00 60.97  ? 380 ILE B N   1 
ATOM   6398  C CA  . ILE B 1 380 ? -6.520  -48.678 27.746  1.00 59.09  ? 380 ILE B CA  1 
ATOM   6399  C C   . ILE B 1 380 ? -6.554  -47.493 28.713  1.00 57.04  ? 380 ILE B C   1 
ATOM   6400  O O   . ILE B 1 380 ? -5.529  -47.115 29.281  1.00 49.84  ? 380 ILE B O   1 
ATOM   6401  C CB  . ILE B 1 380 ? -6.502  -48.220 26.273  1.00 59.23  ? 380 ILE B CB  1 
ATOM   6402  C CG1 . ILE B 1 380 ? -6.363  -49.409 25.315  1.00 54.44  ? 380 ILE B CG1 1 
ATOM   6403  C CG2 . ILE B 1 380 ? -5.413  -47.183 26.068  1.00 53.96  ? 380 ILE B CG2 1 
ATOM   6404  C CD1 . ILE B 1 380 ? -6.379  -49.031 23.850  1.00 54.81  ? 380 ILE B CD1 1 
ATOM   6405  N N   . GLN B 1 381 ? -7.746  -46.901 28.863  1.00 55.24  ? 381 GLN B N   1 
ATOM   6406  C CA  . GLN B 1 381 ? -7.971  -45.811 29.804  1.00 53.83  ? 381 GLN B CA  1 
ATOM   6407  C C   . GLN B 1 381 ? -7.635  -46.293 31.208  1.00 50.95  ? 381 GLN B C   1 
ATOM   6408  O O   . GLN B 1 381 ? -6.876  -45.661 31.936  1.00 51.65  ? 381 GLN B O   1 
ATOM   6409  C CB  . GLN B 1 381 ? -9.438  -45.341 29.786  1.00 58.99  ? 381 GLN B CB  1 
ATOM   6410  C CG  . GLN B 1 381 ? -9.922  -44.728 28.468  1.00 56.47  ? 381 GLN B CG  1 
ATOM   6411  C CD  . GLN B 1 381 ? -9.008  -43.641 27.952  1.00 52.93  ? 381 GLN B CD  1 
ATOM   6412  O OE1 . GLN B 1 381 ? -8.690  -43.594 26.757  1.00 54.68  ? 381 GLN B OE1 1 
ATOM   6413  N NE2 . GLN B 1 381 ? -8.594  -42.769 28.864  1.00 46.55  ? 381 GLN B NE2 1 
ATOM   6414  N N   . TRP B 1 382 ? -8.230  -47.430 31.569  1.00 47.51  ? 382 TRP B N   1 
ATOM   6415  C CA  . TRP B 1 382 ? -8.022  -48.023 32.869  1.00 49.40  ? 382 TRP B CA  1 
ATOM   6416  C C   . TRP B 1 382 ? -6.534  -48.155 33.169  1.00 49.73  ? 382 TRP B C   1 
ATOM   6417  O O   . TRP B 1 382 ? -6.096  -47.808 34.263  1.00 50.36  ? 382 TRP B O   1 
ATOM   6418  C CB  . TRP B 1 382 ? -8.721  -49.378 32.950  1.00 50.13  ? 382 TRP B CB  1 
ATOM   6419  C CG  . TRP B 1 382 ? -8.678  -49.926 34.343  1.00 58.10  ? 382 TRP B CG  1 
ATOM   6420  C CD1 . TRP B 1 382 ? -7.693  -50.687 34.906  1.00 50.97  ? 382 TRP B CD1 1 
ATOM   6421  C CD2 . TRP B 1 382 ? -9.644  -49.667 35.381  1.00 56.32  ? 382 TRP B CD2 1 
ATOM   6422  N NE1 . TRP B 1 382 ? -8.003  -50.957 36.213  1.00 54.46  ? 382 TRP B NE1 1 
ATOM   6423  C CE2 . TRP B 1 382 ? -9.189  -50.341 36.540  1.00 54.82  ? 382 TRP B CE2 1 
ATOM   6424  C CE3 . TRP B 1 382 ? -10.849 -48.958 35.430  1.00 49.66  ? 382 TRP B CE3 1 
ATOM   6425  C CZ2 . TRP B 1 382 ? -9.902  -50.322 37.743  1.00 51.43  ? 382 TRP B CZ2 1 
ATOM   6426  C CZ3 . TRP B 1 382 ? -11.549 -48.934 36.619  1.00 59.23  ? 382 TRP B CZ3 1 
ATOM   6427  C CH2 . TRP B 1 382 ? -11.085 -49.611 37.759  1.00 57.64  ? 382 TRP B CH2 1 
ATOM   6428  N N   . HIS B 1 383 ? -5.769  -48.679 32.204  1.00 51.92  ? 383 HIS B N   1 
ATOM   6429  C CA  . HIS B 1 383 ? -4.359  -48.949 32.423  1.00 54.68  ? 383 HIS B CA  1 
ATOM   6430  C C   . HIS B 1 383 ? -3.614  -47.663 32.766  1.00 55.23  ? 383 HIS B C   1 
ATOM   6431  O O   . HIS B 1 383 ? -2.645  -47.728 33.515  1.00 53.86  ? 383 HIS B O   1 
ATOM   6432  C CB  . HIS B 1 383 ? -3.724  -49.648 31.210  1.00 67.15  ? 383 HIS B CB  1 
ATOM   6433  C CG  . HIS B 1 383 ? -2.226  -49.791 31.268  1.00 74.31  ? 383 HIS B CG  1 
ATOM   6434  N ND1 . HIS B 1 383 ? -1.583  -50.929 31.705  1.00 76.74  ? 383 HIS B ND1 1 
ATOM   6435  C CD2 . HIS B 1 383 ? -1.249  -48.880 30.956  1.00 73.63  ? 383 HIS B CD2 1 
ATOM   6436  C CE1 . HIS B 1 383 ? -0.264  -50.727 31.653  1.00 78.62  ? 383 HIS B CE1 1 
ATOM   6437  N NE2 . HIS B 1 383 ? -0.035  -49.461 31.195  1.00 72.09  ? 383 HIS B NE2 1 
ATOM   6438  N N   . TYR B 1 384 ? -4.051  -46.503 32.248  1.00 58.46  ? 384 TYR B N   1 
ATOM   6439  C CA  . TYR B 1 384 ? -3.341  -45.258 32.519  1.00 62.39  ? 384 TYR B CA  1 
ATOM   6440  C C   . TYR B 1 384 ? -3.966  -44.466 33.670  1.00 59.41  ? 384 TYR B C   1 
ATOM   6441  O O   . TYR B 1 384 ? -3.608  -43.310 33.872  1.00 64.14  ? 384 TYR B O   1 
ATOM   6442  C CB  . TYR B 1 384 ? -3.234  -44.419 31.245  1.00 69.38  ? 384 TYR B CB  1 
ATOM   6443  C CG  . TYR B 1 384 ? -2.350  -45.066 30.214  1.00 76.05  ? 384 TYR B CG  1 
ATOM   6444  C CD1 . TYR B 1 384 ? -0.969  -45.084 30.361  1.00 73.01  ? 384 TYR B CD1 1 
ATOM   6445  C CD2 . TYR B 1 384 ? -2.898  -45.744 29.142  1.00 74.42  ? 384 TYR B CD2 1 
ATOM   6446  C CE1 . TYR B 1 384 ? -0.148  -45.714 29.440  1.00 74.80  ? 384 TYR B CE1 1 
ATOM   6447  C CE2 . TYR B 1 384 ? -2.091  -46.386 28.217  1.00 80.72  ? 384 TYR B CE2 1 
ATOM   6448  C CZ  . TYR B 1 384 ? -0.713  -46.372 28.360  1.00 86.40  ? 384 TYR B CZ  1 
ATOM   6449  O OH  . TYR B 1 384 ? 0.051   -47.018 27.406  1.00 88.14  ? 384 TYR B OH  1 
ATOM   6450  N N   . GLY B 1 385 ? -4.897  -45.073 34.418  1.00 59.36  ? 385 GLY B N   1 
ATOM   6451  C CA  . GLY B 1 385 ? -5.386  -44.488 35.658  1.00 56.34  ? 385 GLY B CA  1 
ATOM   6452  C C   . GLY B 1 385 ? -6.711  -43.737 35.507  1.00 51.94  ? 385 GLY B C   1 
ATOM   6453  O O   . GLY B 1 385 ? -7.205  -43.170 36.475  1.00 51.34  ? 385 GLY B O   1 
ATOM   6454  N N   . VAL B 1 386 ? -7.295  -43.725 34.308  1.00 47.74  ? 386 VAL B N   1 
ATOM   6455  C CA  . VAL B 1 386 ? -8.623  -43.161 34.144  1.00 46.97  ? 386 VAL B CA  1 
ATOM   6456  C C   . VAL B 1 386 ? -9.590  -44.279 34.535  1.00 48.53  ? 386 VAL B C   1 
ATOM   6457  O O   . VAL B 1 386 ? -10.041 -45.065 33.689  1.00 41.74  ? 386 VAL B O   1 
ATOM   6458  C CB  . VAL B 1 386 ? -8.846  -42.615 32.716  1.00 50.61  ? 386 VAL B CB  1 
ATOM   6459  C CG1 . VAL B 1 386 ? -10.147 -41.850 32.570  1.00 54.09  ? 386 VAL B CG1 1 
ATOM   6460  C CG2 . VAL B 1 386 ? -7.695  -41.721 32.270  1.00 53.33  ? 386 VAL B CG2 1 
ATOM   6461  N N   . VAL B 1 387 ? -9.867  -44.349 35.847  1.00 46.00  ? 387 VAL B N   1 
ATOM   6462  C CA  . VAL B 1 387 ? -10.625 -45.437 36.455  1.00 47.27  ? 387 VAL B CA  1 
ATOM   6463  C C   . VAL B 1 387 ? -12.082 -45.036 36.697  1.00 52.30  ? 387 VAL B C   1 
ATOM   6464  O O   . VAL B 1 387 ? -12.890 -45.855 37.157  1.00 54.67  ? 387 VAL B O   1 
ATOM   6465  C CB  . VAL B 1 387 ? -9.956  -45.884 37.767  1.00 49.35  ? 387 VAL B CB  1 
ATOM   6466  C CG1 . VAL B 1 387 ? -8.524  -46.337 37.504  1.00 51.66  ? 387 VAL B CG1 1 
ATOM   6467  C CG2 . VAL B 1 387 ? -10.010 -44.801 38.842  1.00 46.21  ? 387 VAL B CG2 1 
ATOM   6468  N N   . GLU B 1 388 ? -12.407 -43.786 36.337  1.00 53.52  ? 388 GLU B N   1 
ATOM   6469  C CA  . GLU B 1 388 ? -13.710 -43.193 36.559  1.00 48.41  ? 388 GLU B CA  1 
ATOM   6470  C C   . GLU B 1 388 ? -14.546 -43.429 35.296  1.00 50.28  ? 388 GLU B C   1 
ATOM   6471  O O   . GLU B 1 388 ? -14.511 -42.654 34.345  1.00 47.69  ? 388 GLU B O   1 
ATOM   6472  C CB  . GLU B 1 388 ? -13.492 -41.727 36.933  1.00 49.83  ? 388 GLU B CB  1 
ATOM   6473  C CG  . GLU B 1 388 ? -12.520 -41.518 38.111  1.00 48.46  ? 388 GLU B CG  1 
ATOM   6474  C CD  . GLU B 1 388 ? -11.016 -41.367 37.837  1.00 50.69  ? 388 GLU B CD  1 
ATOM   6475  O OE1 . GLU B 1 388 ? -10.539 -41.590 36.664  1.00 46.93  ? 388 GLU B OE1 1 
ATOM   6476  O OE2 . GLU B 1 388 ? -10.282 -41.032 38.825  1.00 55.94  ? 388 GLU B OE2 1 
ATOM   6477  N N   . TYR B 1 389 ? -15.289 -44.538 35.319  1.00 47.54  ? 389 TYR B N   1 
ATOM   6478  C CA  . TYR B 1 389 ? -16.035 -45.073 34.185  1.00 53.18  ? 389 TYR B CA  1 
ATOM   6479  C C   . TYR B 1 389 ? -16.917 -44.030 33.495  1.00 51.97  ? 389 TYR B C   1 
ATOM   6480  O O   . TYR B 1 389 ? -17.001 -43.999 32.268  1.00 52.06  ? 389 TYR B O   1 
ATOM   6481  C CB  . TYR B 1 389 ? -16.945 -46.215 34.658  1.00 54.16  ? 389 TYR B CB  1 
ATOM   6482  C CG  . TYR B 1 389 ? -16.247 -47.373 35.332  1.00 59.91  ? 389 TYR B CG  1 
ATOM   6483  C CD1 . TYR B 1 389 ? -15.506 -48.295 34.603  1.00 55.21  ? 389 TYR B CD1 1 
ATOM   6484  C CD2 . TYR B 1 389 ? -16.332 -47.556 36.712  1.00 66.21  ? 389 TYR B CD2 1 
ATOM   6485  C CE1 . TYR B 1 389 ? -14.885 -49.373 35.218  1.00 59.82  ? 389 TYR B CE1 1 
ATOM   6486  C CE2 . TYR B 1 389 ? -15.706 -48.623 37.341  1.00 58.08  ? 389 TYR B CE2 1 
ATOM   6487  C CZ  . TYR B 1 389 ? -14.971 -49.533 36.592  1.00 59.93  ? 389 TYR B CZ  1 
ATOM   6488  O OH  . TYR B 1 389 ? -14.339 -50.607 37.184  1.00 54.03  ? 389 TYR B OH  1 
ATOM   6489  N N   . ASP B 1 390 ? -17.630 -43.218 34.286  1.00 55.63  ? 390 ASP B N   1 
ATOM   6490  C CA  . ASP B 1 390 ? -18.673 -42.325 33.782  1.00 53.10  ? 390 ASP B CA  1 
ATOM   6491  C C   . ASP B 1 390 ? -18.088 -41.269 32.845  1.00 45.56  ? 390 ASP B C   1 
ATOM   6492  O O   . ASP B 1 390 ? -18.771 -40.816 31.927  1.00 44.39  ? 390 ASP B O   1 
ATOM   6493  C CB  . ASP B 1 390 ? -19.455 -41.702 34.948  1.00 59.49  ? 390 ASP B CB  1 
ATOM   6494  C CG  . ASP B 1 390 ? -20.406 -42.676 35.640  1.00 59.17  ? 390 ASP B CG  1 
ATOM   6495  O OD1 . ASP B 1 390 ? -20.608 -43.796 35.105  1.00 70.81  ? 390 ASP B OD1 1 
ATOM   6496  O OD2 . ASP B 1 390 ? -20.947 -42.312 36.702  1.00 55.87  ? 390 ASP B OD2 1 
ATOM   6497  N N   . PHE B 1 391 ? -16.812 -40.940 33.089  1.00 40.78  ? 391 PHE B N   1 
ATOM   6498  C CA  . PHE B 1 391 ? -16.045 -39.978 32.323  1.00 38.33  ? 391 PHE B CA  1 
ATOM   6499  C C   . PHE B 1 391 ? -15.685 -40.470 30.920  1.00 37.81  ? 391 PHE B C   1 
ATOM   6500  O O   . PHE B 1 391 ? -15.326 -39.678 30.051  1.00 37.34  ? 391 PHE B O   1 
ATOM   6501  C CB  . PHE B 1 391 ? -14.752 -39.637 33.075  1.00 36.92  ? 391 PHE B CB  1 
ATOM   6502  C CG  . PHE B 1 391 ? -14.084 -38.404 32.526  1.00 41.89  ? 391 PHE B CG  1 
ATOM   6503  C CD1 . PHE B 1 391 ? -14.637 -37.137 32.730  1.00 37.25  ? 391 PHE B CD1 1 
ATOM   6504  C CD2 . PHE B 1 391 ? -12.958 -38.510 31.714  1.00 43.13  ? 391 PHE B CD2 1 
ATOM   6505  C CE1 . PHE B 1 391 ? -14.068 -36.017 32.151  1.00 34.04  ? 391 PHE B CE1 1 
ATOM   6506  C CE2 . PHE B 1 391 ? -12.367 -37.378 31.169  1.00 40.06  ? 391 PHE B CE2 1 
ATOM   6507  C CZ  . PHE B 1 391 ? -12.925 -36.138 31.391  1.00 37.95  ? 391 PHE B CZ  1 
ATOM   6508  N N   . TYR B 1 392 ? -15.755 -41.774 30.655  1.00 40.34  ? 392 TYR B N   1 
ATOM   6509  C CA  . TYR B 1 392 ? -15.311 -42.266 29.355  1.00 43.09  ? 392 TYR B CA  1 
ATOM   6510  C C   . TYR B 1 392 ? -16.159 -41.627 28.254  1.00 42.98  ? 392 TYR B C   1 
ATOM   6511  O O   . TYR B 1 392 ? -15.692 -41.368 27.144  1.00 43.55  ? 392 TYR B O   1 
ATOM   6512  C CB  . TYR B 1 392 ? -15.360 -43.800 29.288  1.00 43.72  ? 392 TYR B CB  1 
ATOM   6513  C CG  . TYR B 1 392 ? -14.373 -44.533 30.161  1.00 42.58  ? 392 TYR B CG  1 
ATOM   6514  C CD1 . TYR B 1 392 ? -13.316 -43.885 30.779  1.00 45.90  ? 392 TYR B CD1 1 
ATOM   6515  C CD2 . TYR B 1 392 ? -14.519 -45.884 30.410  1.00 45.61  ? 392 TYR B CD2 1 
ATOM   6516  C CE1 . TYR B 1 392 ? -12.421 -44.560 31.593  1.00 48.48  ? 392 TYR B CE1 1 
ATOM   6517  C CE2 . TYR B 1 392 ? -13.630 -46.576 31.229  1.00 51.31  ? 392 TYR B CE2 1 
ATOM   6518  C CZ  . TYR B 1 392 ? -12.573 -45.914 31.830  1.00 49.66  ? 392 TYR B CZ  1 
ATOM   6519  O OH  . TYR B 1 392 ? -11.672 -46.574 32.656  1.00 51.09  ? 392 TYR B OH  1 
ATOM   6520  N N   . THR B 1 393 ? -17.421 -41.365 28.572  1.00 45.60  ? 393 THR B N   1 
ATOM   6521  C CA  . THR B 1 393 ? -18.353 -40.829 27.594  1.00 47.60  ? 393 THR B CA  1 
ATOM   6522  C C   . THR B 1 393 ? -17.977 -39.383 27.274  1.00 39.44  ? 393 THR B C   1 
ATOM   6523  O O   . THR B 1 393 ? -18.148 -38.931 26.159  1.00 32.31  ? 393 THR B O   1 
ATOM   6524  C CB  . THR B 1 393 ? -19.776 -41.023 28.131  1.00 49.34  ? 393 THR B CB  1 
ATOM   6525  O OG1 . THR B 1 393 ? -19.867 -42.376 28.598  1.00 52.40  ? 393 THR B OG1 1 
ATOM   6526  C CG2 . THR B 1 393 ? -20.838 -40.717 27.099  1.00 46.94  ? 393 THR B CG2 1 
ATOM   6527  N N   . VAL B 1 394 ? -17.459 -38.649 28.258  1.00 40.79  ? 394 VAL B N   1 
ATOM   6528  C CA  . VAL B 1 394 ? -16.961 -37.311 27.998  1.00 39.46  ? 394 VAL B CA  1 
ATOM   6529  C C   . VAL B 1 394 ? -15.815 -37.352 26.982  1.00 41.65  ? 394 VAL B C   1 
ATOM   6530  O O   . VAL B 1 394 ? -15.694 -36.423 26.185  1.00 40.10  ? 394 VAL B O   1 
ATOM   6531  C CB  . VAL B 1 394 ? -16.512 -36.599 29.287  1.00 37.03  ? 394 VAL B CB  1 
ATOM   6532  C CG1 . VAL B 1 394 ? -15.902 -35.246 28.972  1.00 35.71  ? 394 VAL B CG1 1 
ATOM   6533  C CG2 . VAL B 1 394 ? -17.636 -36.445 30.292  1.00 32.93  ? 394 VAL B CG2 1 
ATOM   6534  N N   . LEU B 1 395 ? -14.959 -38.388 27.011  1.00 38.40  ? 395 LEU B N   1 
ATOM   6535  C CA  . LEU B 1 395 ? -13.851 -38.483 26.059  1.00 35.43  ? 395 LEU B CA  1 
ATOM   6536  C C   . LEU B 1 395 ? -14.378 -38.680 24.651  1.00 33.79  ? 395 LEU B C   1 
ATOM   6537  O O   . LEU B 1 395 ? -13.909 -38.065 23.694  1.00 42.71  ? 395 LEU B O   1 
ATOM   6538  C CB  . LEU B 1 395 ? -12.967 -39.678 26.411  1.00 35.88  ? 395 LEU B CB  1 
ATOM   6539  C CG  . LEU B 1 395 ? -12.238 -39.590 27.744  1.00 38.28  ? 395 LEU B CG  1 
ATOM   6540  C CD1 . LEU B 1 395 ? -11.614 -40.928 28.087  1.00 41.57  ? 395 LEU B CD1 1 
ATOM   6541  C CD2 . LEU B 1 395 ? -11.171 -38.511 27.695  1.00 41.66  ? 395 LEU B CD2 1 
ATOM   6542  N N   . PHE B 1 396 ? -15.323 -39.615 24.554  1.00 38.06  ? 396 PHE B N   1 
ATOM   6543  C CA  . PHE B 1 396 ? -16.067 -39.879 23.334  1.00 39.93  ? 396 PHE B CA  1 
ATOM   6544  C C   . PHE B 1 396 ? -16.565 -38.544 22.778  1.00 41.83  ? 396 PHE B C   1 
ATOM   6545  O O   . PHE B 1 396 ? -16.299 -38.232 21.613  1.00 45.34  ? 396 PHE B O   1 
ATOM   6546  C CB  . PHE B 1 396 ? -17.160 -40.908 23.653  1.00 43.48  ? 396 PHE B CB  1 
ATOM   6547  C CG  . PHE B 1 396 ? -17.834 -41.564 22.479  1.00 48.95  ? 396 PHE B CG  1 
ATOM   6548  C CD1 . PHE B 1 396 ? -17.872 -40.971 21.222  1.00 49.87  ? 396 PHE B CD1 1 
ATOM   6549  C CD2 . PHE B 1 396 ? -18.464 -42.788 22.643  1.00 55.44  ? 396 PHE B CD2 1 
ATOM   6550  C CE1 . PHE B 1 396 ? -18.497 -41.596 20.153  1.00 47.63  ? 396 PHE B CE1 1 
ATOM   6551  C CE2 . PHE B 1 396 ? -19.097 -43.407 21.570  1.00 56.70  ? 396 PHE B CE2 1 
ATOM   6552  C CZ  . PHE B 1 396 ? -19.089 -42.820 20.319  1.00 48.09  ? 396 PHE B CZ  1 
ATOM   6553  N N   . GLY B 1 397 ? -17.225 -37.750 23.646  1.00 37.33  ? 397 GLY B N   1 
ATOM   6554  C CA  . GLY B 1 397 ? -17.842 -36.480 23.292  1.00 36.03  ? 397 GLY B CA  1 
ATOM   6555  C C   . GLY B 1 397 ? -16.861 -35.442 22.736  1.00 38.12  ? 397 GLY B C   1 
ATOM   6556  O O   . GLY B 1 397 ? -17.217 -34.658 21.847  1.00 31.09  ? 397 GLY B O   1 
ATOM   6557  N N   . ILE B 1 398 ? -15.647 -35.396 23.299  1.00 33.21  ? 398 ILE B N   1 
ATOM   6558  C CA  . ILE B 1 398 ? -14.621 -34.512 22.780  1.00 37.68  ? 398 ILE B CA  1 
ATOM   6559  C C   . ILE B 1 398 ? -14.225 -34.963 21.358  1.00 39.66  ? 398 ILE B C   1 
ATOM   6560  O O   . ILE B 1 398 ? -14.192 -34.157 20.417  1.00 35.80  ? 398 ILE B O   1 
ATOM   6561  C CB  . ILE B 1 398 ? -13.425 -34.483 23.760  1.00 37.09  ? 398 ILE B CB  1 
ATOM   6562  C CG1 . ILE B 1 398 ? -13.823 -33.911 25.123  1.00 31.61  ? 398 ILE B CG1 1 
ATOM   6563  C CG2 . ILE B 1 398 ? -12.249 -33.718 23.166  1.00 39.75  ? 398 ILE B CG2 1 
ATOM   6564  C CD1 . ILE B 1 398 ? -12.853 -34.222 26.220  1.00 30.21  ? 398 ILE B CD1 1 
ATOM   6565  N N   . GLY B 1 399 ? -13.978 -36.270 21.193  1.00 36.69  ? 399 GLY B N   1 
ATOM   6566  C CA  . GLY B 1 399 ? -13.565 -36.814 19.912  1.00 44.09  ? 399 GLY B CA  1 
ATOM   6567  C C   . GLY B 1 399 ? -14.604 -36.616 18.808  1.00 40.84  ? 399 GLY B C   1 
ATOM   6568  O O   . GLY B 1 399 ? -14.281 -36.071 17.758  1.00 40.80  ? 399 GLY B O   1 
ATOM   6569  N N   . ARG B 1 400 ? -15.846 -37.035 19.081  1.00 39.22  ? 400 ARG B N   1 
ATOM   6570  C CA  . ARG B 1 400 ? -16.957 -36.939 18.146  1.00 40.92  ? 400 ARG B CA  1 
ATOM   6571  C C   . ARG B 1 400 ? -17.214 -35.505 17.659  1.00 38.84  ? 400 ARG B C   1 
ATOM   6572  O O   . ARG B 1 400 ? -17.802 -35.277 16.600  1.00 33.22  ? 400 ARG B O   1 
ATOM   6573  C CB  . ARG B 1 400 ? -18.179 -37.554 18.838  1.00 44.50  ? 400 ARG B CB  1 
ATOM   6574  C CG  . ARG B 1 400 ? -19.435 -37.635 17.981  1.00 46.75  ? 400 ARG B CG  1 
ATOM   6575  C CD  . ARG B 1 400 ? -19.194 -38.085 16.536  1.00 51.84  ? 400 ARG B CD  1 
ATOM   6576  N NE  . ARG B 1 400 ? -18.490 -39.356 16.399  1.00 53.25  ? 400 ARG B NE  1 
ATOM   6577  C CZ  . ARG B 1 400 ? -19.049 -40.553 16.567  1.00 56.07  ? 400 ARG B CZ  1 
ATOM   6578  N NH1 . ARG B 1 400 ? -20.359 -40.645 16.722  1.00 64.56  ? 400 ARG B NH1 1 
ATOM   6579  N NH2 . ARG B 1 400 ? -18.296 -41.647 16.587  1.00 53.30  ? 400 ARG B NH2 1 
ATOM   6580  N N   . ALA B 1 401 ? -16.776 -34.494 18.404  1.00 42.88  ? 401 ALA B N   1 
ATOM   6581  C CA  . ALA B 1 401 ? -17.067 -33.128 17.982  1.00 41.76  ? 401 ALA B CA  1 
ATOM   6582  C C   . ALA B 1 401 ? -16.323 -32.792 16.692  1.00 41.12  ? 401 ALA B C   1 
ATOM   6583  O O   . ALA B 1 401 ? -16.789 -31.942 15.950  1.00 39.39  ? 401 ALA B O   1 
ATOM   6584  C CB  . ALA B 1 401 ? -16.702 -32.153 19.072  1.00 46.06  ? 401 ALA B CB  1 
ATOM   6585  N N   . LEU B 1 402 ? -15.163 -33.436 16.449  1.00 37.77  ? 402 LEU B N   1 
ATOM   6586  C CA  . LEU B 1 402 ? -14.342 -33.152 15.270  1.00 38.37  ? 402 LEU B CA  1 
ATOM   6587  C C   . LEU B 1 402 ? -15.179 -33.360 14.021  1.00 35.58  ? 402 LEU B C   1 
ATOM   6588  O O   . LEU B 1 402 ? -15.268 -32.495 13.164  1.00 41.73  ? 402 LEU B O   1 
ATOM   6589  C CB  . LEU B 1 402 ? -13.123 -34.088 15.242  1.00 38.92  ? 402 LEU B CB  1 
ATOM   6590  C CG  . LEU B 1 402 ? -12.062 -33.903 16.338  1.00 43.40  ? 402 LEU B CG  1 
ATOM   6591  C CD1 . LEU B 1 402 ? -11.133 -35.115 16.454  1.00 46.38  ? 402 LEU B CD1 1 
ATOM   6592  C CD2 . LEU B 1 402 ? -11.227 -32.643 16.094  1.00 45.03  ? 402 LEU B CD2 1 
ATOM   6593  N N   . GLY B 1 403 ? -15.828 -34.522 13.967  1.00 37.22  ? 403 GLY B N   1 
ATOM   6594  C CA  . GLY B 1 403 ? -16.647 -34.885 12.832  1.00 37.54  ? 403 GLY B CA  1 
ATOM   6595  C C   . GLY B 1 403 ? -17.937 -34.086 12.791  1.00 40.63  ? 403 GLY B C   1 
ATOM   6596  O O   . GLY B 1 403 ? -18.325 -33.608 11.732  1.00 45.41  ? 403 GLY B O   1 
ATOM   6597  N N   . VAL B 1 404 ? -18.584 -33.935 13.952  1.00 44.08  ? 404 VAL B N   1 
ATOM   6598  C CA  . VAL B 1 404 ? -19.914 -33.353 14.004  1.00 40.78  ? 404 VAL B CA  1 
ATOM   6599  C C   . VAL B 1 404 ? -19.859 -31.879 13.632  1.00 43.14  ? 404 VAL B C   1 
ATOM   6600  O O   . VAL B 1 404 ? -20.691 -31.434 12.838  1.00 41.98  ? 404 VAL B O   1 
ATOM   6601  C CB  . VAL B 1 404 ? -20.565 -33.539 15.380  1.00 46.42  ? 404 VAL B CB  1 
ATOM   6602  C CG1 . VAL B 1 404 ? -21.801 -32.664 15.537  1.00 48.35  ? 404 VAL B CG1 1 
ATOM   6603  C CG2 . VAL B 1 404 ? -20.903 -35.007 15.600  1.00 51.15  ? 404 VAL B CG2 1 
ATOM   6604  N N   . LEU B 1 405 ? -18.875 -31.152 14.191  1.00 39.27  ? 405 LEU B N   1 
ATOM   6605  C CA  . LEU B 1 405 ? -18.759 -29.719 13.957  1.00 40.73  ? 405 LEU B CA  1 
ATOM   6606  C C   . LEU B 1 405 ? -18.409 -29.453 12.493  1.00 39.49  ? 405 LEU B C   1 
ATOM   6607  O O   . LEU B 1 405 ? -18.957 -28.530 11.905  1.00 46.57  ? 405 LEU B O   1 
ATOM   6608  C CB  . LEU B 1 405 ? -17.745 -29.092 14.928  1.00 40.91  ? 405 LEU B CB  1 
ATOM   6609  C CG  . LEU B 1 405 ? -18.131 -29.131 16.418  1.00 45.62  ? 405 LEU B CG  1 
ATOM   6610  C CD1 . LEU B 1 405 ? -17.063 -28.502 17.294  1.00 46.18  ? 405 LEU B CD1 1 
ATOM   6611  C CD2 . LEU B 1 405 ? -19.478 -28.466 16.690  1.00 46.68  ? 405 LEU B CD2 1 
ATOM   6612  N N   . ALA B 1 406 ? -17.521 -30.267 11.911  1.00 43.79  ? 406 ALA B N   1 
ATOM   6613  C CA  . ALA B 1 406 ? -17.192 -30.188 10.490  1.00 45.20  ? 406 ALA B CA  1 
ATOM   6614  C C   . ALA B 1 406 ? -18.442 -30.449 9.650   1.00 50.08  ? 406 ALA B C   1 
ATOM   6615  O O   . ALA B 1 406 ? -18.735 -29.707 8.704   1.00 51.47  ? 406 ALA B O   1 
ATOM   6616  C CB  . ALA B 1 406 ? -16.088 -31.165 10.157  1.00 44.58  ? 406 ALA B CB  1 
ATOM   6617  N N   . ASN B 1 407 ? -19.212 -31.472 10.036  1.00 45.68  ? 407 ASN B N   1 
ATOM   6618  C CA  . ASN B 1 407 ? -20.451 -31.747 9.347   1.00 47.96  ? 407 ASN B CA  1 
ATOM   6619  C C   . ASN B 1 407 ? -21.406 -30.551 9.440   1.00 46.38  ? 407 ASN B C   1 
ATOM   6620  O O   . ASN B 1 407 ? -22.064 -30.246 8.459   1.00 43.61  ? 407 ASN B O   1 
ATOM   6621  C CB  . ASN B 1 407 ? -21.073 -33.061 9.818   1.00 53.95  ? 407 ASN B CB  1 
ATOM   6622  C CG  . ASN B 1 407 ? -22.074 -33.615 8.823   1.00 61.06  ? 407 ASN B CG  1 
ATOM   6623  O OD1 . ASN B 1 407 ? -23.212 -33.908 9.183   1.00 77.81  ? 407 ASN B OD1 1 
ATOM   6624  N ND2 . ASN B 1 407 ? -21.669 -33.745 7.568   1.00 69.40  ? 407 ASN B ND2 1 
ATOM   6625  N N   . LEU B 1 408 ? -21.472 -29.832 10.570  1.00 45.57  ? 408 LEU B N   1 
ATOM   6626  C CA  . LEU B 1 408 ? -22.416 -28.723 10.695  1.00 45.21  ? 408 LEU B CA  1 
ATOM   6627  C C   . LEU B 1 408 ? -22.039 -27.550 9.808   1.00 46.28  ? 408 LEU B C   1 
ATOM   6628  O O   . LEU B 1 408 ? -22.913 -26.799 9.383   1.00 41.78  ? 408 LEU B O   1 
ATOM   6629  C CB  . LEU B 1 408 ? -22.469 -28.208 12.136  1.00 49.62  ? 408 LEU B CB  1 
ATOM   6630  C CG  . LEU B 1 408 ? -23.023 -29.159 13.196  1.00 50.57  ? 408 LEU B CG  1 
ATOM   6631  C CD1 . LEU B 1 408 ? -23.504 -28.346 14.387  1.00 46.86  ? 408 LEU B CD1 1 
ATOM   6632  C CD2 . LEU B 1 408 ? -24.141 -30.044 12.652  1.00 48.56  ? 408 LEU B CD2 1 
ATOM   6633  N N   . VAL B 1 409 ? -20.734 -27.356 9.597   1.00 50.31  ? 409 VAL B N   1 
ATOM   6634  C CA  . VAL B 1 409 ? -20.279 -26.282 8.726   1.00 49.32  ? 409 VAL B CA  1 
ATOM   6635  C C   . VAL B 1 409 ? -20.760 -26.547 7.300   1.00 43.69  ? 409 VAL B C   1 
ATOM   6636  O O   . VAL B 1 409 ? -21.314 -25.661 6.654   1.00 42.00  ? 409 VAL B O   1 
ATOM   6637  C CB  . VAL B 1 409 ? -18.750 -26.111 8.781   1.00 50.83  ? 409 VAL B CB  1 
ATOM   6638  C CG1 . VAL B 1 409 ? -18.288 -25.089 7.761   1.00 51.57  ? 409 VAL B CG1 1 
ATOM   6639  C CG2 . VAL B 1 409 ? -18.265 -25.732 10.168  1.00 46.49  ? 409 VAL B CG2 1 
ATOM   6640  N N   . TRP B 1 410 ? -20.542 -27.778 6.824   1.00 44.91  ? 410 TRP B N   1 
ATOM   6641  C CA  . TRP B 1 410 ? -20.971 -28.185 5.496   1.00 46.00  ? 410 TRP B CA  1 
ATOM   6642  C C   . TRP B 1 410 ? -22.492 -28.126 5.337   1.00 42.24  ? 410 TRP B C   1 
ATOM   6643  O O   . TRP B 1 410 ? -22.967 -27.627 4.337   1.00 45.22  ? 410 TRP B O   1 
ATOM   6644  C CB  . TRP B 1 410 ? -20.371 -29.553 5.164   1.00 45.04  ? 410 TRP B CB  1 
ATOM   6645  C CG  . TRP B 1 410 ? -18.962 -29.403 4.682   1.00 52.63  ? 410 TRP B CG  1 
ATOM   6646  C CD1 . TRP B 1 410 ? -17.818 -29.569 5.406   1.00 56.27  ? 410 TRP B CD1 1 
ATOM   6647  C CD2 . TRP B 1 410 ? -18.547 -28.998 3.361   1.00 55.68  ? 410 TRP B CD2 1 
ATOM   6648  N NE1 . TRP B 1 410 ? -16.722 -29.284 4.635   1.00 54.50  ? 410 TRP B NE1 1 
ATOM   6649  C CE2 . TRP B 1 410 ? -17.137 -28.950 3.371   1.00 56.91  ? 410 TRP B CE2 1 
ATOM   6650  C CE3 . TRP B 1 410 ? -19.228 -28.689 2.174   1.00 55.45  ? 410 TRP B CE3 1 
ATOM   6651  C CZ2 . TRP B 1 410 ? -16.402 -28.623 2.229   1.00 59.97  ? 410 TRP B CZ2 1 
ATOM   6652  C CZ3 . TRP B 1 410 ? -18.504 -28.380 1.043   1.00 55.83  ? 410 TRP B CZ3 1 
ATOM   6653  C CH2 . TRP B 1 410 ? -17.109 -28.338 1.078   1.00 56.49  ? 410 TRP B CH2 1 
ATOM   6654  N N   . ASP B 1 411 ? -23.262 -28.545 6.339   1.00 41.75  ? 411 ASP B N   1 
ATOM   6655  C CA  . ASP B 1 411 ? -24.713 -28.496 6.247   1.00 45.34  ? 411 ASP B CA  1 
ATOM   6656  C C   . ASP B 1 411 ? -25.178 -27.072 5.947   1.00 40.79  ? 411 ASP B C   1 
ATOM   6657  O O   . ASP B 1 411 ? -26.133 -26.875 5.191   1.00 41.89  ? 411 ASP B O   1 
ATOM   6658  C CB  . ASP B 1 411 ? -25.351 -29.001 7.547   1.00 58.04  ? 411 ASP B CB  1 
ATOM   6659  C CG  . ASP B 1 411 ? -25.242 -30.499 7.830   1.00 72.02  ? 411 ASP B CG  1 
ATOM   6660  O OD1 . ASP B 1 411 ? -24.938 -31.271 6.872   1.00 76.63  ? 411 ASP B OD1 1 
ATOM   6661  O OD2 . ASP B 1 411 ? -25.448 -30.894 9.030   1.00 73.52  ? 411 ASP B OD2 1 
ATOM   6662  N N   . ARG B 1 412 ? -24.510 -26.081 6.552   1.00 40.54  ? 412 ARG B N   1 
ATOM   6663  C CA  . ARG B 1 412 ? -24.861 -24.680 6.365   1.00 41.83  ? 412 ARG B CA  1 
ATOM   6664  C C   . ARG B 1 412 ? -24.293 -24.171 5.047   1.00 41.38  ? 412 ARG B C   1 
ATOM   6665  O O   . ARG B 1 412 ? -24.931 -23.374 4.361   1.00 39.04  ? 412 ARG B O   1 
ATOM   6666  C CB  . ARG B 1 412 ? -24.327 -23.811 7.512   1.00 49.55  ? 412 ARG B CB  1 
ATOM   6667  C CG  . ARG B 1 412 ? -25.020 -24.021 8.857   1.00 52.18  ? 412 ARG B CG  1 
ATOM   6668  C CD  . ARG B 1 412 ? -26.468 -23.539 8.913   1.00 54.83  ? 412 ARG B CD  1 
ATOM   6669  N NE  . ARG B 1 412 ? -27.433 -24.366 8.192   1.00 57.65  ? 412 ARG B NE  1 
ATOM   6670  C CZ  . ARG B 1 412 ? -27.648 -25.655 8.432   1.00 61.35  ? 412 ARG B CZ  1 
ATOM   6671  N NH1 . ARG B 1 412 ? -28.453 -26.356 7.650   1.00 58.71  ? 412 ARG B NH1 1 
ATOM   6672  N NH2 . ARG B 1 412 ? -27.041 -26.239 9.453   1.00 67.25  ? 412 ARG B NH2 1 
ATOM   6673  N N   . ALA B 1 413 ? -23.084 -24.640 4.721   1.00 43.54  ? 413 ALA B N   1 
ATOM   6674  C CA  . ALA B 1 413 ? -22.421 -24.333 3.461   1.00 44.61  ? 413 ALA B CA  1 
ATOM   6675  C C   . ALA B 1 413 ? -23.336 -24.695 2.303   1.00 46.88  ? 413 ALA B C   1 
ATOM   6676  O O   . ALA B 1 413 ? -23.601 -23.850 1.462   1.00 47.93  ? 413 ALA B O   1 
ATOM   6677  C CB  . ALA B 1 413 ? -21.106 -25.079 3.353   1.00 43.17  ? 413 ALA B CB  1 
ATOM   6678  N N   . LEU B 1 414 ? -23.873 -25.927 2.321   1.00 52.24  ? 414 LEU B N   1 
ATOM   6679  C CA  . LEU B 1 414 ? -24.668 -26.458 1.215   1.00 52.81  ? 414 LEU B CA  1 
ATOM   6680  C C   . LEU B 1 414 ? -26.148 -26.114 1.362   1.00 51.23  ? 414 LEU B C   1 
ATOM   6681  O O   . LEU B 1 414 ? -26.952 -26.562 0.549   1.00 57.70  ? 414 LEU B O   1 
ATOM   6682  C CB  . LEU B 1 414 ? -24.481 -27.978 1.151   1.00 52.05  ? 414 LEU B CB  1 
ATOM   6683  C CG  . LEU B 1 414 ? -23.041 -28.472 1.008   1.00 50.85  ? 414 LEU B CG  1 
ATOM   6684  C CD1 . LEU B 1 414 ? -23.009 -29.996 0.914   1.00 49.59  ? 414 LEU B CD1 1 
ATOM   6685  C CD2 . LEU B 1 414 ? -22.364 -27.840 -0.204  1.00 54.46  ? 414 LEU B CD2 1 
ATOM   6686  N N   . GLY B 1 415 ? -26.501 -25.381 2.426   1.00 54.28  ? 415 GLY B N   1 
ATOM   6687  C CA  . GLY B 1 415 ? -27.832 -24.827 2.590   1.00 57.52  ? 415 GLY B CA  1 
ATOM   6688  C C   . GLY B 1 415 ? -28.899 -25.884 2.852   1.00 57.39  ? 415 GLY B C   1 
ATOM   6689  O O   . GLY B 1 415 ? -30.055 -25.640 2.508   1.00 54.25  ? 415 GLY B O   1 
ATOM   6690  N N   . TYR B 1 416 ? -28.541 -27.016 3.493   1.00 53.85  ? 416 TYR B N   1 
ATOM   6691  C CA  . TYR B 1 416 ? -29.520 -28.080 3.712   1.00 60.06  ? 416 TYR B CA  1 
ATOM   6692  C C   . TYR B 1 416 ? -30.675 -27.567 4.578   1.00 64.12  ? 416 TYR B C   1 
ATOM   6693  O O   . TYR B 1 416 ? -30.476 -26.781 5.514   1.00 59.55  ? 416 TYR B O   1 
ATOM   6694  C CB  . TYR B 1 416 ? -28.923 -29.313 4.388   1.00 54.77  ? 416 TYR B CB  1 
ATOM   6695  C CG  . TYR B 1 416 ? -27.956 -30.133 3.573   1.00 59.12  ? 416 TYR B CG  1 
ATOM   6696  C CD1 . TYR B 1 416 ? -27.890 -30.082 2.186   1.00 58.50  ? 416 TYR B CD1 1 
ATOM   6697  C CD2 . TYR B 1 416 ? -27.061 -30.967 4.224   1.00 61.33  ? 416 TYR B CD2 1 
ATOM   6698  C CE1 . TYR B 1 416 ? -26.969 -30.849 1.482   1.00 57.47  ? 416 TYR B CE1 1 
ATOM   6699  C CE2 . TYR B 1 416 ? -26.144 -31.741 3.530   1.00 58.23  ? 416 TYR B CE2 1 
ATOM   6700  C CZ  . TYR B 1 416 ? -26.069 -31.660 2.156   1.00 56.52  ? 416 TYR B CZ  1 
ATOM   6701  O OH  . TYR B 1 416 ? -25.087 -32.441 1.575   1.00 63.07  ? 416 TYR B OH  1 
ATOM   6702  N N   . ALA B 1 417 ? -31.895 -28.031 4.268   1.00 65.06  ? 417 ALA B N   1 
ATOM   6703  C CA  . ALA B 1 417 ? -33.085 -27.468 4.887   1.00 63.81  ? 417 ALA B CA  1 
ATOM   6704  C C   . ALA B 1 417 ? -33.381 -28.205 6.186   1.00 55.94  ? 417 ALA B C   1 
ATOM   6705  O O   . ALA B 1 417 ? -32.771 -29.227 6.493   1.00 50.53  ? 417 ALA B O   1 
ATOM   6706  C CB  . ALA B 1 417 ? -34.264 -27.524 3.945   1.00 63.88  ? 417 ALA B CB  1 
ATOM   6707  N N   . ILE B 1 418 ? -34.358 -27.664 6.908   1.00 52.07  ? 418 ILE B N   1 
ATOM   6708  C CA  . ILE B 1 418 ? -34.810 -28.218 8.175   1.00 52.29  ? 418 ILE B CA  1 
ATOM   6709  C C   . ILE B 1 418 ? -35.261 -29.671 7.964   1.00 57.34  ? 418 ILE B C   1 
ATOM   6710  O O   . ILE B 1 418 ? -35.894 -30.000 6.944   1.00 52.16  ? 418 ILE B O   1 
ATOM   6711  C CB  . ILE B 1 418 ? -35.903 -27.284 8.746   1.00 50.30  ? 418 ILE B CB  1 
ATOM   6712  C CG1 . ILE B 1 418 ? -36.266 -27.638 10.183  1.00 50.10  ? 418 ILE B CG1 1 
ATOM   6713  C CG2 . ILE B 1 418 ? -37.143 -27.222 7.853   1.00 51.79  ? 418 ILE B CG2 1 
ATOM   6714  C CD1 . ILE B 1 418 ? -37.211 -26.647 10.842  1.00 48.55  ? 418 ILE B CD1 1 
ATOM   6715  N N   . GLU B 1 419 ? -34.874 -30.549 8.908   1.00 48.97  ? 419 GLU B N   1 
ATOM   6716  C CA  . GLU B 1 419 ? -35.249 -31.952 8.877   1.00 51.40  ? 419 GLU B CA  1 
ATOM   6717  C C   . GLU B 1 419 ? -36.645 -32.089 9.495   1.00 55.67  ? 419 GLU B C   1 
ATOM   6718  O O   . GLU B 1 419 ? -36.839 -31.827 10.683  1.00 49.01  ? 419 GLU B O   1 
ATOM   6719  C CB  . GLU B 1 419 ? -34.179 -32.772 9.589   1.00 57.25  ? 419 GLU B CB  1 
ATOM   6720  C CG  . GLU B 1 419 ? -34.445 -34.276 9.672   1.00 64.51  ? 419 GLU B CG  1 
ATOM   6721  C CD  . GLU B 1 419 ? -33.284 -35.100 10.215  1.00 68.46  ? 419 GLU B CD  1 
ATOM   6722  O OE1 . GLU B 1 419 ? -32.181 -34.925 9.655   1.00 83.73  ? 419 GLU B OE1 1 
ATOM   6723  O OE2 . GLU B 1 419 ? -33.479 -35.933 11.157  1.00 57.27  ? 419 GLU B OE2 1 
ATOM   6724  N N   . ARG B 1 420 ? -37.621 -32.453 8.649   1.00 55.51  ? 420 ARG B N   1 
ATOM   6725  C CA  . ARG B 1 420 ? -39.020 -32.487 9.030   1.00 53.55  ? 420 ARG B CA  1 
ATOM   6726  C C   . ARG B 1 420 ? -39.654 -33.666 8.294   1.00 56.93  ? 420 ARG B C   1 
ATOM   6727  O O   . ARG B 1 420 ? -40.299 -33.473 7.260   1.00 54.78  ? 420 ARG B O   1 
ATOM   6728  C CB  . ARG B 1 420 ? -39.696 -31.149 8.696   1.00 57.47  ? 420 ARG B CB  1 
ATOM   6729  C CG  . ARG B 1 420 ? -40.919 -30.793 9.540   1.00 56.83  ? 420 ARG B CG  1 
ATOM   6730  C CD  . ARG B 1 420 ? -41.900 -31.924 9.817   1.00 59.12  ? 420 ARG B CD  1 
ATOM   6731  N NE  . ARG B 1 420 ? -43.100 -31.515 10.552  1.00 63.85  ? 420 ARG B NE  1 
ATOM   6732  C CZ  . ARG B 1 420 ? -43.931 -32.336 11.203  1.00 62.71  ? 420 ARG B CZ  1 
ATOM   6733  N NH1 . ARG B 1 420 ? -43.857 -33.645 11.023  1.00 56.07  ? 420 ARG B NH1 1 
ATOM   6734  N NH2 . ARG B 1 420 ? -44.829 -31.843 12.048  1.00 63.21  ? 420 ARG B NH2 1 
ATOM   6735  N N   . PRO B 1 421 ? -39.448 -34.922 8.768   1.00 52.96  ? 421 PRO B N   1 
ATOM   6736  C CA  . PRO B 1 421 ? -40.147 -36.078 8.213   1.00 52.79  ? 421 PRO B CA  1 
ATOM   6737  C C   . PRO B 1 421 ? -41.607 -36.064 8.650   1.00 54.54  ? 421 PRO B C   1 
ATOM   6738  O O   . PRO B 1 421 ? -41.997 -35.219 9.448   1.00 56.30  ? 421 PRO B O   1 
ATOM   6739  C CB  . PRO B 1 421 ? -39.397 -37.287 8.795   1.00 50.88  ? 421 PRO B CB  1 
ATOM   6740  C CG  . PRO B 1 421 ? -38.826 -36.773 10.094  1.00 55.27  ? 421 PRO B CG  1 
ATOM   6741  C CD  . PRO B 1 421 ? -38.551 -35.296 9.872   1.00 52.05  ? 421 PRO B CD  1 
ATOM   6742  N N   . LYS B 1 422 ? -42.386 -37.025 8.140   1.00 56.18  ? 422 LYS B N   1 
ATOM   6743  C CA  . LYS B 1 422 ? -43.799 -37.141 8.458   1.00 53.36  ? 422 LYS B CA  1 
ATOM   6744  C C   . LYS B 1 422 ? -44.006 -38.317 9.411   1.00 52.39  ? 422 LYS B C   1 
ATOM   6745  O O   . LYS B 1 422 ? -43.350 -39.339 9.288   1.00 44.94  ? 422 LYS B O   1 
ATOM   6746  C CB  . LYS B 1 422 ? -44.612 -37.299 7.168   1.00 54.49  ? 422 LYS B CB  1 
ATOM   6747  C CG  . LYS B 1 422 ? -46.115 -37.121 7.314   1.00 57.04  ? 422 LYS B CG  1 
ATOM   6748  C CD  . LYS B 1 422 ? -46.542 -35.699 7.645   1.00 67.21  ? 422 LYS B CD  1 
ATOM   6749  C CE  . LYS B 1 422 ? -48.050 -35.510 7.708   1.00 71.12  ? 422 LYS B CE  1 
ATOM   6750  N NZ  . LYS B 1 422 ? -48.631 -35.901 9.016   1.00 63.71  ? 422 LYS B NZ  1 
ATOM   6751  N N   . SER B 1 423 ? -44.923 -38.143 10.373  1.00 62.55  ? 423 SER B N   1 
ATOM   6752  C CA  . SER B 1 423 ? -45.326 -39.194 11.296  1.00 64.29  ? 423 SER B CA  1 
ATOM   6753  C C   . SER B 1 423 ? -46.621 -39.859 10.831  1.00 61.89  ? 423 SER B C   1 
ATOM   6754  O O   . SER B 1 423 ? -47.437 -39.264 10.124  1.00 54.00  ? 423 SER B O   1 
ATOM   6755  C CB  . SER B 1 423 ? -45.514 -38.638 12.681  1.00 67.43  ? 423 SER B CB  1 
ATOM   6756  O OG  . SER B 1 423 ? -44.381 -37.882 13.063  1.00 84.22  ? 423 SER B OG  1 
ATOM   6757  N N   . VAL B 1 424 ? -46.837 -41.085 11.312  1.00 57.66  ? 424 VAL B N   1 
ATOM   6758  C CA  . VAL B 1 424 ? -48.079 -41.796 11.066  1.00 56.08  ? 424 VAL B CA  1 
ATOM   6759  C C   . VAL B 1 424 ? -48.485 -42.520 12.346  1.00 60.46  ? 424 VAL B C   1 
ATOM   6760  O O   . VAL B 1 424 ? -47.646 -42.770 13.208  1.00 65.52  ? 424 VAL B O   1 
ATOM   6761  C CB  . VAL B 1 424 ? -47.920 -42.766 9.882   1.00 55.79  ? 424 VAL B CB  1 
ATOM   6762  C CG1 . VAL B 1 424 ? -47.441 -42.030 8.638   1.00 60.22  ? 424 VAL B CG1 1 
ATOM   6763  C CG2 . VAL B 1 424 ? -46.992 -43.932 10.201  1.00 52.87  ? 424 VAL B CG2 1 
ATOM   6764  N N   . THR B 1 425 ? -49.774 -42.855 12.459  1.00 62.53  ? 425 THR B N   1 
ATOM   6765  C CA  . THR B 1 425 ? -50.271 -43.551 13.634  1.00 61.20  ? 425 THR B CA  1 
ATOM   6766  C C   . THR B 1 425 ? -50.182 -45.053 13.409  1.00 53.56  ? 425 THR B C   1 
ATOM   6767  O O   . THR B 1 425 ? -49.882 -45.498 12.310  1.00 53.85  ? 425 THR B O   1 
ATOM   6768  C CB  . THR B 1 425 ? -51.702 -43.111 13.961  1.00 64.50  ? 425 THR B CB  1 
ATOM   6769  O OG1 . THR B 1 425 ? -52.584 -43.643 12.970  1.00 72.76  ? 425 THR B OG1 1 
ATOM   6770  C CG2 . THR B 1 425 ? -51.829 -41.605 14.027  1.00 69.48  ? 425 THR B CG2 1 
ATOM   6771  N N   . THR B 1 426 ? -50.442 -45.807 14.475  1.00 55.11  ? 426 THR B N   1 
ATOM   6772  C CA  . THR B 1 426 ? -50.608 -47.243 14.389  1.00 55.84  ? 426 THR B CA  1 
ATOM   6773  C C   . THR B 1 426 ? -51.882 -47.566 13.612  1.00 56.68  ? 426 THR B C   1 
ATOM   6774  O O   . THR B 1 426 ? -51.881 -48.489 12.822  1.00 51.82  ? 426 THR B O   1 
ATOM   6775  C CB  . THR B 1 426 ? -50.621 -47.855 15.786  1.00 53.37  ? 426 THR B CB  1 
ATOM   6776  O OG1 . THR B 1 426 ? -49.457 -47.378 16.460  1.00 57.31  ? 426 THR B OG1 1 
ATOM   6777  C CG2 . THR B 1 426 ? -50.607 -49.365 15.759  1.00 55.73  ? 426 THR B CG2 1 
ATOM   6778  N N   . ASP B 1 427 ? -52.948 -46.782 13.827  1.00 62.96  ? 427 ASP B N   1 
ATOM   6779  C CA  . ASP B 1 427 ? -54.204 -46.900 13.092  1.00 61.76  ? 427 ASP B CA  1 
ATOM   6780  C C   . ASP B 1 427 ? -53.963 -46.825 11.587  1.00 63.49  ? 427 ASP B C   1 
ATOM   6781  O O   . ASP B 1 427 ? -54.516 -47.624 10.834  1.00 76.67  ? 427 ASP B O   1 
ATOM   6782  C CB  . ASP B 1 427 ? -55.226 -45.828 13.496  1.00 62.24  ? 427 ASP B CB  1 
ATOM   6783  C CG  . ASP B 1 427 ? -55.920 -46.090 14.834  1.00 65.72  ? 427 ASP B CG  1 
ATOM   6784  O OD1 . ASP B 1 427 ? -55.417 -46.899 15.616  1.00 69.45  ? 427 ASP B OD1 1 
ATOM   6785  O OD2 . ASP B 1 427 ? -56.974 -45.490 15.094  1.00 72.24  ? 427 ASP B OD2 1 
ATOM   6786  N N   . MET B 1 428 ? -53.149 -45.858 11.160  1.00 63.32  ? 428 MET B N   1 
ATOM   6787  C CA  . MET B 1 428 ? -52.807 -45.668 9.759   1.00 62.56  ? 428 MET B CA  1 
ATOM   6788  C C   . MET B 1 428 ? -51.983 -46.841 9.227   1.00 60.78  ? 428 MET B C   1 
ATOM   6789  O O   . MET B 1 428 ? -52.253 -47.319 8.129   1.00 61.55  ? 428 MET B O   1 
ATOM   6790  C CB  . MET B 1 428 ? -52.034 -44.357 9.580   1.00 66.93  ? 428 MET B CB  1 
ATOM   6791  C CG  . MET B 1 428 ? -52.974 -43.151 9.566   1.00 74.80  ? 428 MET B CG  1 
ATOM   6792  S SD  . MET B 1 428 ? -52.165 -41.540 9.715   1.00 83.65  ? 428 MET B SD  1 
ATOM   6793  C CE  . MET B 1 428 ? -51.315 -41.441 8.132   1.00 79.49  ? 428 MET B CE  1 
ATOM   6794  N N   . LEU B 1 429 ? -50.992 -47.321 9.993   1.00 62.82  ? 429 LEU B N   1 
ATOM   6795  C CA  . LEU B 1 429 ? -50.200 -48.470 9.575   1.00 61.04  ? 429 LEU B CA  1 
ATOM   6796  C C   . LEU B 1 429 ? -51.060 -49.727 9.461   1.00 66.44  ? 429 LEU B C   1 
ATOM   6797  O O   . LEU B 1 429 ? -50.708 -50.665 8.743   1.00 73.87  ? 429 LEU B O   1 
ATOM   6798  C CB  . LEU B 1 429 ? -49.108 -48.730 10.613  1.00 64.83  ? 429 LEU B CB  1 
ATOM   6799  C CG  . LEU B 1 429 ? -47.935 -47.763 10.627  1.00 70.01  ? 429 LEU B CG  1 
ATOM   6800  C CD1 . LEU B 1 429 ? -46.964 -48.168 11.728  1.00 71.37  ? 429 LEU B CD1 1 
ATOM   6801  C CD2 . LEU B 1 429 ? -47.249 -47.714 9.262   1.00 69.31  ? 429 LEU B CD2 1 
ATOM   6802  N N   . GLU B 1 430 ? -52.127 -49.768 10.264  1.00 67.22  ? 430 GLU B N   1 
ATOM   6803  C CA  . GLU B 1 430 ? -53.013 -50.911 10.351  1.00 63.31  ? 430 GLU B CA  1 
ATOM   6804  C C   . GLU B 1 430 ? -53.965 -50.909 9.162   1.00 65.55  ? 430 GLU B C   1 
ATOM   6805  O O   . GLU B 1 430 ? -54.241 -51.970 8.627   1.00 62.39  ? 430 GLU B O   1 
ATOM   6806  C CB  . GLU B 1 430 ? -53.756 -50.901 11.686  1.00 58.74  ? 430 GLU B CB  1 
ATOM   6807  C CG  . GLU B 1 430 ? -52.966 -51.565 12.809  1.00 61.00  ? 430 GLU B CG  1 
ATOM   6808  C CD  . GLU B 1 430 ? -53.671 -51.601 14.161  1.00 62.55  ? 430 GLU B CD  1 
ATOM   6809  O OE1 . GLU B 1 430 ? -54.649 -50.821 14.354  1.00 55.98  ? 430 GLU B OE1 1 
ATOM   6810  O OE2 . GLU B 1 430 ? -53.240 -52.408 15.025  1.00 63.98  ? 430 GLU B OE2 1 
ATOM   6811  N N   . LYS B 1 431 ? -54.440 -49.726 8.746   1.00 78.59  ? 431 LYS B N   1 
ATOM   6812  C CA  . LYS B 1 431 ? -55.196 -49.594 7.509   1.00 82.97  ? 431 LYS B CA  1 
ATOM   6813  C C   . LYS B 1 431 ? -54.357 -50.115 6.327   1.00 87.90  ? 431 LYS B C   1 
ATOM   6814  O O   . LYS B 1 431 ? -54.827 -50.991 5.600   1.00 103.08 ? 431 LYS B O   1 
ATOM   6815  C CB  . LYS B 1 431 ? -55.668 -48.142 7.332   1.00 87.31  ? 431 LYS B CB  1 
ATOM   6816  C CG  . LYS B 1 431 ? -57.109 -47.946 6.866   1.00 100.96 ? 431 LYS B CG  1 
ATOM   6817  C CD  . LYS B 1 431 ? -57.621 -48.943 5.808   1.00 123.04 ? 431 LYS B CD  1 
ATOM   6818  C CE  . LYS B 1 431 ? -56.878 -48.944 4.480   1.00 131.72 ? 431 LYS B CE  1 
ATOM   6819  N NZ  . LYS B 1 431 ? -57.532 -48.102 3.445   1.00 127.65 ? 431 LYS B NZ  1 
ATOM   6820  N N   . TRP B 1 432 ? -53.107 -49.635 6.147   1.00 91.82  ? 432 TRP B N   1 
ATOM   6821  C CA  . TRP B 1 432 ? -52.250 -50.048 5.035   1.00 92.65  ? 432 TRP B CA  1 
ATOM   6822  C C   . TRP B 1 432 ? -51.895 -51.536 5.074   1.00 83.20  ? 432 TRP B C   1 
ATOM   6823  O O   . TRP B 1 432 ? -51.519 -52.098 4.047   1.00 76.85  ? 432 TRP B O   1 
ATOM   6824  C CB  . TRP B 1 432 ? -50.947 -49.228 4.962   1.00 105.97 ? 432 TRP B CB  1 
ATOM   6825  C CG  . TRP B 1 432 ? -51.100 -47.863 4.375   1.00 120.72 ? 432 TRP B CG  1 
ATOM   6826  C CD1 . TRP B 1 432 ? -51.761 -47.543 3.226   1.00 130.74 ? 432 TRP B CD1 1 
ATOM   6827  C CD2 . TRP B 1 432 ? -50.555 -46.632 4.891   1.00 140.53 ? 432 TRP B CD2 1 
ATOM   6828  N NE1 . TRP B 1 432 ? -51.681 -46.195 3.000   1.00 151.81 ? 432 TRP B NE1 1 
ATOM   6829  C CE2 . TRP B 1 432 ? -50.950 -45.606 4.003   1.00 146.37 ? 432 TRP B CE2 1 
ATOM   6830  C CE3 . TRP B 1 432 ? -49.767 -46.292 6.002   1.00 137.02 ? 432 TRP B CE3 1 
ATOM   6831  C CZ2 . TRP B 1 432 ? -50.597 -44.268 4.207   1.00 130.67 ? 432 TRP B CZ2 1 
ATOM   6832  C CZ3 . TRP B 1 432 ? -49.420 -44.973 6.202   1.00 120.79 ? 432 TRP B CZ3 1 
ATOM   6833  C CH2 . TRP B 1 432 ? -49.840 -43.974 5.320   1.00 125.69 ? 432 TRP B CH2 1 
ATOM   6834  N N   . ALA B 1 433 ? -51.931 -52.173 6.248   1.00 82.22  ? 433 ALA B N   1 
ATOM   6835  C CA  . ALA B 1 433 ? -51.666 -53.603 6.304   1.00 84.40  ? 433 ALA B CA  1 
ATOM   6836  C C   . ALA B 1 433 ? -52.923 -54.393 5.938   1.00 83.32  ? 433 ALA B C   1 
ATOM   6837  O O   . ALA B 1 433 ? -52.830 -55.587 5.664   1.00 76.80  ? 433 ALA B O   1 
ATOM   6838  C CB  . ALA B 1 433 ? -51.167 -53.985 7.673   1.00 88.75  ? 433 ALA B CB  1 
ATOM   6839  N N   . GLY B 1 434 ? -54.072 -53.731 6.051   1.00 89.11  ? 434 GLY B N   1 
ATOM   6840  C CA  . GLY B 1 434 ? -55.353 -54.416 5.832   1.00 87.99  ? 434 GLY B CA  1 
ATOM   6841  C C   . GLY B 1 434 ? -55.787 -55.131 7.094   1.00 83.07  ? 434 GLY B C   1 
ATOM   6842  O O   . GLY B 1 434 ? -55.539 -56.343 7.176   1.00 87.15  ? 434 GLY B O   1 
ATOM   6843  N N   . ILE B 1 435 ? -56.413 -54.422 8.039   1.00 76.51  ? 435 ILE B N   1 
ATOM   6844  C CA  . ILE B 1 435 ? -56.768 -55.054 9.311   1.00 74.25  ? 435 ILE B CA  1 
ATOM   6845  C C   . ILE B 1 435 ? -58.166 -54.590 9.761   1.00 69.80  ? 435 ILE B C   1 
ATOM   6846  O O   . ILE B 1 435 ? -58.249 -53.488 10.341  1.00 61.21  ? 435 ILE B O   1 
ATOM   6847  C CB  . ILE B 1 435 ? -55.662 -54.815 10.371  1.00 68.48  ? 435 ILE B CB  1 
ATOM   6848  C CG1 . ILE B 1 435 ? -54.345 -55.476 9.942   1.00 66.50  ? 435 ILE B CG1 1 
ATOM   6849  C CG2 . ILE B 1 435 ? -56.116 -55.266 11.755  1.00 68.01  ? 435 ILE B CG2 1 
ATOM   6850  C CD1 . ILE B 1 435 ? -53.256 -55.554 10.997  1.00 65.63  ? 435 ILE B CD1 1 
ATOM   6851  N N   . SER C 1 2   ? -51.858 6.843   38.894  1.00 78.57  ? 2   SER C N   1 
ATOM   6852  C CA  . SER C 1 2   ? -52.497 6.925   40.233  1.00 79.99  ? 2   SER C CA  1 
ATOM   6853  C C   . SER C 1 2   ? -53.051 8.330   40.455  1.00 78.74  ? 2   SER C C   1 
ATOM   6854  O O   . SER C 1 2   ? -52.847 9.226   39.631  1.00 64.96  ? 2   SER C O   1 
ATOM   6855  C CB  . SER C 1 2   ? -51.510 6.549   41.312  1.00 83.35  ? 2   SER C CB  1 
ATOM   6856  O OG  . SER C 1 2   ? -50.284 7.255   41.140  1.00 75.68  ? 2   SER C OG  1 
ATOM   6857  N N   . PHE C 1 3   ? -53.727 8.508   41.595  1.00 77.69  ? 3   PHE C N   1 
ATOM   6858  C CA  . PHE C 1 3   ? -54.124 9.833   42.030  1.00 79.85  ? 3   PHE C CA  1 
ATOM   6859  C C   . PHE C 1 3   ? -52.884 10.716  42.224  1.00 68.14  ? 3   PHE C C   1 
ATOM   6860  O O   . PHE C 1 3   ? -52.879 11.856  41.757  1.00 63.22  ? 3   PHE C O   1 
ATOM   6861  C CB  . PHE C 1 3   ? -54.992 9.776   43.295  1.00 86.90  ? 3   PHE C CB  1 
ATOM   6862  C CG  . PHE C 1 3   ? -55.619 11.110  43.616  1.00 113.84 ? 3   PHE C CG  1 
ATOM   6863  C CD1 . PHE C 1 3   ? -56.412 11.761  42.672  1.00 128.53 ? 3   PHE C CD1 1 
ATOM   6864  C CD2 . PHE C 1 3   ? -55.385 11.747  44.828  1.00 117.85 ? 3   PHE C CD2 1 
ATOM   6865  C CE1 . PHE C 1 3   ? -56.974 13.003  42.938  1.00 130.64 ? 3   PHE C CE1 1 
ATOM   6866  C CE2 . PHE C 1 3   ? -55.952 12.990  45.088  1.00 127.45 ? 3   PHE C CE2 1 
ATOM   6867  C CZ  . PHE C 1 3   ? -56.742 13.618  44.146  1.00 128.37 ? 3   PHE C CZ  1 
ATOM   6868  N N   . LEU C 1 4   ? -51.841 10.167  42.879  1.00 56.92  ? 4   LEU C N   1 
ATOM   6869  C CA  . LEU C 1 4   ? -50.619 10.888  43.225  1.00 57.09  ? 4   LEU C CA  1 
ATOM   6870  C C   . LEU C 1 4   ? -49.915 11.440  41.984  1.00 52.55  ? 4   LEU C C   1 
ATOM   6871  O O   . LEU C 1 4   ? -49.523 12.602  41.962  1.00 49.66  ? 4   LEU C O   1 
ATOM   6872  C CB  . LEU C 1 4   ? -49.685 9.957   44.015  1.00 59.80  ? 4   LEU C CB  1 
ATOM   6873  C CG  . LEU C 1 4   ? -48.328 10.538  44.438  1.00 57.92  ? 4   LEU C CG  1 
ATOM   6874  C CD1 . LEU C 1 4   ? -48.476 11.867  45.170  1.00 59.48  ? 4   LEU C CD1 1 
ATOM   6875  C CD2 . LEU C 1 4   ? -47.556 9.554   45.318  1.00 53.93  ? 4   LEU C CD2 1 
ATOM   6876  N N   . LYS C 1 5   ? -49.772 10.622  40.942  1.00 48.19  ? 5   LYS C N   1 
ATOM   6877  C CA  . LYS C 1 5   ? -49.123 11.073  39.728  1.00 52.07  ? 5   LYS C CA  1 
ATOM   6878  C C   . LYS C 1 5   ? -49.939 12.163  39.024  1.00 58.23  ? 5   LYS C C   1 
ATOM   6879  O O   . LYS C 1 5   ? -49.352 13.118  38.505  1.00 55.96  ? 5   LYS C O   1 
ATOM   6880  C CB  . LYS C 1 5   ? -48.878 9.868   38.824  1.00 60.98  ? 5   LYS C CB  1 
ATOM   6881  C CG  . LYS C 1 5   ? -47.989 10.134  37.621  1.00 62.90  ? 5   LYS C CG  1 
ATOM   6882  C CD  . LYS C 1 5   ? -47.239 8.900   37.178  1.00 63.88  ? 5   LYS C CD  1 
ATOM   6883  C CE  . LYS C 1 5   ? -46.575 9.076   35.827  1.00 65.97  ? 5   LYS C CE  1 
ATOM   6884  N NZ  . LYS C 1 5   ? -45.632 7.961   35.554  1.00 58.18  ? 5   LYS C NZ  1 
ATOM   6885  N N   . GLU C 1 6   ? -51.277 12.031  38.990  1.00 58.90  ? 6   GLU C N   1 
ATOM   6886  C CA  . GLU C 1 6   ? -52.120 13.068  38.393  1.00 68.07  ? 6   GLU C CA  1 
ATOM   6887  C C   . GLU C 1 6   ? -52.019 14.375  39.186  1.00 56.16  ? 6   GLU C C   1 
ATOM   6888  O O   . GLU C 1 6   ? -51.854 15.434  38.596  1.00 56.76  ? 6   GLU C O   1 
ATOM   6889  C CB  . GLU C 1 6   ? -53.591 12.647  38.324  1.00 80.08  ? 6   GLU C CB  1 
ATOM   6890  C CG  . GLU C 1 6   ? -53.937 11.692  37.190  1.00 91.85  ? 6   GLU C CG  1 
ATOM   6891  C CD  . GLU C 1 6   ? -55.325 11.056  37.271  1.00 106.49 ? 6   GLU C CD  1 
ATOM   6892  O OE1 . GLU C 1 6   ? -56.054 11.275  38.282  1.00 98.38  ? 6   GLU C OE1 1 
ATOM   6893  O OE2 . GLU C 1 6   ? -55.691 10.338  36.316  1.00 107.90 ? 6   GLU C OE2 1 
ATOM   6894  N N   . LYS C 1 7   ? -52.135 14.275  40.515  1.00 54.57  ? 7   LYS C N   1 
ATOM   6895  C CA  . LYS C 1 7   ? -52.064 15.401  41.438  1.00 54.20  ? 7   LYS C CA  1 
ATOM   6896  C C   . LYS C 1 7   ? -50.724 16.124  41.299  1.00 54.04  ? 7   LYS C C   1 
ATOM   6897  O O   . LYS C 1 7   ? -50.643 17.353  41.362  1.00 52.70  ? 7   LYS C O   1 
ATOM   6898  C CB  . LYS C 1 7   ? -52.300 14.867  42.860  1.00 60.36  ? 7   LYS C CB  1 
ATOM   6899  C CG  . LYS C 1 7   ? -51.898 15.757  44.036  1.00 64.01  ? 7   LYS C CG  1 
ATOM   6900  C CD  . LYS C 1 7   ? -52.664 17.042  44.181  1.00 65.47  ? 7   LYS C CD  1 
ATOM   6901  C CE  . LYS C 1 7   ? -54.092 16.825  44.624  1.00 76.60  ? 7   LYS C CE  1 
ATOM   6902  N NZ  . LYS C 1 7   ? -54.984 17.861  44.058  1.00 84.70  ? 7   LYS C NZ  1 
ATOM   6903  N N   . LEU C 1 8   ? -49.664 15.341  41.108  1.00 57.23  ? 8   LEU C N   1 
ATOM   6904  C CA  . LEU C 1 8   ? -48.312 15.869  41.020  1.00 53.88  ? 8   LEU C CA  1 
ATOM   6905  C C   . LEU C 1 8   ? -48.129 16.536  39.660  1.00 43.82  ? 8   LEU C C   1 
ATOM   6906  O O   . LEU C 1 8   ? -47.416 17.506  39.545  1.00 47.11  ? 8   LEU C O   1 
ATOM   6907  C CB  . LEU C 1 8   ? -47.339 14.705  41.259  1.00 55.00  ? 8   LEU C CB  1 
ATOM   6908  C CG  . LEU C 1 8   ? -45.848 14.989  41.095  1.00 57.65  ? 8   LEU C CG  1 
ATOM   6909  C CD1 . LEU C 1 8   ? -45.335 16.025  42.074  1.00 60.84  ? 8   LEU C CD1 1 
ATOM   6910  C CD2 . LEU C 1 8   ? -45.061 13.704  41.268  1.00 64.41  ? 8   LEU C CD2 1 
ATOM   6911  N N   . ALA C 1 9   ? -48.814 16.049  38.635  1.00 50.94  ? 9   ALA C N   1 
ATOM   6912  C CA  . ALA C 1 9   ? -48.749 16.677  37.320  1.00 55.40  ? 9   ALA C CA  1 
ATOM   6913  C C   . ALA C 1 9   ? -49.400 18.059  37.355  1.00 52.41  ? 9   ALA C C   1 
ATOM   6914  O O   . ALA C 1 9   ? -48.960 18.954  36.629  1.00 47.70  ? 9   ALA C O   1 
ATOM   6915  C CB  . ALA C 1 9   ? -49.401 15.791  36.280  1.00 54.02  ? 9   ALA C CB  1 
ATOM   6916  N N   . GLU C 1 10  ? -50.451 18.199  38.185  1.00 52.30  ? 10  GLU C N   1 
ATOM   6917  C CA  . GLU C 1 10  ? -51.180 19.448  38.329  1.00 52.32  ? 10  GLU C CA  1 
ATOM   6918  C C   . GLU C 1 10  ? -50.263 20.496  38.943  1.00 52.73  ? 10  GLU C C   1 
ATOM   6919  O O   . GLU C 1 10  ? -50.216 21.636  38.479  1.00 52.40  ? 10  GLU C O   1 
ATOM   6920  C CB  . GLU C 1 10  ? -52.402 19.299  39.232  1.00 54.08  ? 10  GLU C CB  1 
ATOM   6921  C CG  . GLU C 1 10  ? -53.538 18.540  38.571  1.00 68.51  ? 10  GLU C CG  1 
ATOM   6922  C CD  . GLU C 1 10  ? -54.658 18.067  39.495  1.00 80.86  ? 10  GLU C CD  1 
ATOM   6923  O OE1 . GLU C 1 10  ? -54.621 18.367  40.732  1.00 78.11  ? 10  GLU C OE1 1 
ATOM   6924  O OE2 . GLU C 1 10  ? -55.579 17.386  38.978  1.00 73.00  ? 10  GLU C OE2 1 
ATOM   6925  N N   . LYS C 1 11  ? -49.559 20.101  40.014  1.00 46.73  ? 11  LYS C N   1 
ATOM   6926  C CA  . LYS C 1 11  ? -48.685 21.010  40.740  1.00 40.99  ? 11  LYS C CA  1 
ATOM   6927  C C   . LYS C 1 11  ? -47.527 21.457  39.853  1.00 40.08  ? 11  LYS C C   1 
ATOM   6928  O O   . LYS C 1 11  ? -47.008 22.558  40.001  1.00 46.84  ? 11  LYS C O   1 
ATOM   6929  C CB  . LYS C 1 11  ? -48.147 20.329  41.993  1.00 40.97  ? 11  LYS C CB  1 
ATOM   6930  C CG  . LYS C 1 11  ? -49.191 19.955  43.025  1.00 41.76  ? 11  LYS C CG  1 
ATOM   6931  C CD  . LYS C 1 11  ? -49.618 21.098  43.898  1.00 46.63  ? 11  LYS C CD  1 
ATOM   6932  C CE  . LYS C 1 11  ? -50.888 20.766  44.664  1.00 54.66  ? 11  LYS C CE  1 
ATOM   6933  N NZ  . LYS C 1 11  ? -50.938 21.473  45.966  1.00 54.75  ? 11  LYS C NZ  1 
ATOM   6934  N N   . ILE C 1 12  ? -47.095 20.574  38.951  1.00 42.28  ? 12  ILE C N   1 
ATOM   6935  C CA  . ILE C 1 12  ? -45.942 20.840  38.105  1.00 42.13  ? 12  ILE C CA  1 
ATOM   6936  C C   . ILE C 1 12  ? -46.315 21.917  37.094  1.00 46.12  ? 12  ILE C C   1 
ATOM   6937  O O   . ILE C 1 12  ? -45.536 22.838  36.862  1.00 40.44  ? 12  ILE C O   1 
ATOM   6938  C CB  . ILE C 1 12  ? -45.445 19.531  37.457  1.00 39.39  ? 12  ILE C CB  1 
ATOM   6939  C CG1 . ILE C 1 12  ? -44.687 18.680  38.489  1.00 38.55  ? 12  ILE C CG1 1 
ATOM   6940  C CG2 . ILE C 1 12  ? -44.599 19.817  36.222  1.00 38.84  ? 12  ILE C CG2 1 
ATOM   6941  C CD1 . ILE C 1 12  ? -44.374 17.259  38.059  1.00 37.04  ? 12  ILE C CD1 1 
ATOM   6942  N N   . ALA C 1 13  ? -47.525 21.782  36.531  1.00 47.38  ? 13  ALA C N   1 
ATOM   6943  C CA  . ALA C 1 13  ? -48.055 22.744  35.582  1.00 49.01  ? 13  ALA C CA  1 
ATOM   6944  C C   . ALA C 1 13  ? -48.264 24.112  36.236  1.00 44.13  ? 13  ALA C C   1 
ATOM   6945  O O   . ALA C 1 13  ? -48.014 25.112  35.579  1.00 38.54  ? 13  ALA C O   1 
ATOM   6946  C CB  . ALA C 1 13  ? -49.334 22.206  34.986  1.00 49.27  ? 13  ALA C CB  1 
ATOM   6947  N N   . GLN C 1 14  ? -48.724 24.154  37.498  1.00 44.14  ? 14  GLN C N   1 
ATOM   6948  C CA  . GLN C 1 14  ? -48.815 25.407  38.250  1.00 51.07  ? 14  GLN C CA  1 
ATOM   6949  C C   . GLN C 1 14  ? -47.432 26.046  38.478  1.00 52.97  ? 14  GLN C C   1 
ATOM   6950  O O   . GLN C 1 14  ? -47.318 27.271  38.458  1.00 56.37  ? 14  GLN C O   1 
ATOM   6951  C CB  . GLN C 1 14  ? -49.459 25.215  39.629  1.00 50.36  ? 14  GLN C CB  1 
ATOM   6952  C CG  . GLN C 1 14  ? -50.976 25.148  39.658  1.00 56.74  ? 14  GLN C CG  1 
ATOM   6953  C CD  . GLN C 1 14  ? -51.446 24.278  40.812  1.00 67.08  ? 14  GLN C CD  1 
ATOM   6954  O OE1 . GLN C 1 14  ? -51.088 24.477  41.979  1.00 66.21  ? 14  GLN C OE1 1 
ATOM   6955  N NE2 . GLN C 1 14  ? -52.264 23.281  40.510  1.00 69.25  ? 14  GLN C NE2 1 
ATOM   6956  N N   . HIS C 1 15  ? -46.376 25.235  38.690  1.00 55.95  ? 15  HIS C N   1 
ATOM   6957  C CA  . HIS C 1 15  ? -45.099 25.735  39.196  1.00 52.34  ? 15  HIS C CA  1 
ATOM   6958  C C   . HIS C 1 15  ? -44.168 26.164  38.057  1.00 46.55  ? 15  HIS C C   1 
ATOM   6959  O O   . HIS C 1 15  ? -43.311 27.038  38.230  1.00 36.63  ? 15  HIS C O   1 
ATOM   6960  C CB  . HIS C 1 15  ? -44.453 24.660  40.094  1.00 56.46  ? 15  HIS C CB  1 
ATOM   6961  C CG  . HIS C 1 15  ? -43.361 25.123  41.017  1.00 55.30  ? 15  HIS C CG  1 
ATOM   6962  N ND1 . HIS C 1 15  ? -42.185 25.708  40.599  1.00 56.05  ? 15  HIS C ND1 1 
ATOM   6963  C CD2 . HIS C 1 15  ? -43.313 25.067  42.389  1.00 59.32  ? 15  HIS C CD2 1 
ATOM   6964  C CE1 . HIS C 1 15  ? -41.435 25.992  41.668  1.00 55.85  ? 15  HIS C CE1 1 
ATOM   6965  N NE2 . HIS C 1 15  ? -42.127 25.625  42.797  1.00 54.27  ? 15  HIS C NE2 1 
ATOM   6966  N N   . ARG C 1 16  ? -44.315 25.535  36.887  1.00 43.65  ? 16  ARG C N   1 
ATOM   6967  C CA  . ARG C 1 16  ? -43.383 25.788  35.800  1.00 46.89  ? 16  ARG C CA  1 
ATOM   6968  C C   . ARG C 1 16  ? -43.436 27.269  35.408  1.00 50.90  ? 16  ARG C C   1 
ATOM   6969  O O   . ARG C 1 16  ? -42.388 27.884  35.258  1.00 50.54  ? 16  ARG C O   1 
ATOM   6970  C CB  . ARG C 1 16  ? -43.621 24.828  34.619  1.00 48.69  ? 16  ARG C CB  1 
ATOM   6971  C CG  . ARG C 1 16  ? -43.028 23.437  34.816  1.00 49.61  ? 16  ARG C CG  1 
ATOM   6972  C CD  . ARG C 1 16  ? -42.807 22.637  33.538  1.00 51.27  ? 16  ARG C CD  1 
ATOM   6973  N NE  . ARG C 1 16  ? -43.575 21.396  33.406  1.00 47.35  ? 16  ARG C NE  1 
ATOM   6974  C CZ  . ARG C 1 16  ? -43.067 20.211  33.054  1.00 44.77  ? 16  ARG C CZ  1 
ATOM   6975  N NH1 . ARG C 1 16  ? -42.280 19.527  33.861  1.00 47.08  ? 16  ARG C NH1 1 
ATOM   6976  N NH2 . ARG C 1 16  ? -43.452 19.639  31.932  1.00 46.15  ? 16  ARG C NH2 1 
ATOM   6977  N N   . PRO C 1 17  ? -44.619 27.908  35.218  1.00 62.71  ? 17  PRO C N   1 
ATOM   6978  C CA  . PRO C 1 17  ? -44.679 29.334  34.869  1.00 59.71  ? 17  PRO C CA  1 
ATOM   6979  C C   . PRO C 1 17  ? -43.929 30.255  35.839  1.00 54.80  ? 17  PRO C C   1 
ATOM   6980  O O   . PRO C 1 17  ? -43.168 31.121  35.402  1.00 53.35  ? 17  PRO C O   1 
ATOM   6981  C CB  . PRO C 1 17  ? -46.189 29.641  34.882  1.00 59.46  ? 17  PRO C CB  1 
ATOM   6982  C CG  . PRO C 1 17  ? -46.834 28.320  34.564  1.00 58.38  ? 17  PRO C CG  1 
ATOM   6983  C CD  . PRO C 1 17  ? -45.964 27.298  35.270  1.00 63.77  ? 17  PRO C CD  1 
ATOM   6984  N N   . ARG C 1 18  ? -44.131 30.047  37.152  1.00 52.65  ? 18  ARG C N   1 
ATOM   6985  C CA  . ARG C 1 18  ? -43.424 30.803  38.184  1.00 54.72  ? 18  ARG C CA  1 
ATOM   6986  C C   . ARG C 1 18  ? -41.916 30.803  37.942  1.00 55.36  ? 18  ARG C C   1 
ATOM   6987  O O   . ARG C 1 18  ? -41.293 31.849  38.062  1.00 54.97  ? 18  ARG C O   1 
ATOM   6988  C CB  . ARG C 1 18  ? -43.724 30.227  39.568  1.00 51.98  ? 18  ARG C CB  1 
ATOM   6989  C CG  . ARG C 1 18  ? -45.179 30.400  39.977  1.00 54.18  ? 18  ARG C CG  1 
ATOM   6990  C CD  . ARG C 1 18  ? -45.560 29.762  41.300  1.00 53.73  ? 18  ARG C CD  1 
ATOM   6991  N NE  . ARG C 1 18  ? -44.728 30.188  42.414  1.00 55.19  ? 18  ARG C NE  1 
ATOM   6992  C CZ  . ARG C 1 18  ? -44.337 29.403  43.421  1.00 52.25  ? 18  ARG C CZ  1 
ATOM   6993  N NH1 . ARG C 1 18  ? -44.585 28.099  43.387  1.00 48.44  ? 18  ARG C NH1 1 
ATOM   6994  N NH2 . ARG C 1 18  ? -43.696 29.947  44.445  1.00 47.35  ? 18  ARG C NH2 1 
ATOM   6995  N N   . THR C 1 19  ? -41.381 29.619  37.598  1.00 59.72  ? 19  THR C N   1 
ATOM   6996  C CA  . THR C 1 19  ? -39.962 29.375  37.375  1.00 65.24  ? 19  THR C CA  1 
ATOM   6997  C C   . THR C 1 19  ? -39.542 30.046  36.067  1.00 60.17  ? 19  THR C C   1 
ATOM   6998  O O   . THR C 1 19  ? -38.528 30.734  36.039  1.00 57.38  ? 19  THR C O   1 
ATOM   6999  C CB  . THR C 1 19  ? -39.631 27.859  37.408  1.00 67.22  ? 19  THR C CB  1 
ATOM   7000  O OG1 . THR C 1 19  ? -39.842 27.286  38.707  1.00 61.91  ? 19  THR C OG1 1 
ATOM   7001  C CG2 . THR C 1 19  ? -38.207 27.530  36.998  1.00 57.57  ? 19  THR C CG2 1 
ATOM   7002  N N   . THR C 1 20  ? -40.323 29.845  34.996  1.00 62.52  ? 20  THR C N   1 
ATOM   7003  C CA  . THR C 1 20  ? -40.008 30.393  33.678  1.00 66.27  ? 20  THR C CA  1 
ATOM   7004  C C   . THR C 1 20  ? -39.937 31.917  33.721  1.00 62.80  ? 20  THR C C   1 
ATOM   7005  O O   . THR C 1 20  ? -39.176 32.523  32.969  1.00 60.73  ? 20  THR C O   1 
ATOM   7006  C CB  . THR C 1 20  ? -41.055 30.031  32.608  1.00 61.83  ? 20  THR C CB  1 
ATOM   7007  O OG1 . THR C 1 20  ? -41.473 28.679  32.803  1.00 76.71  ? 20  THR C OG1 1 
ATOM   7008  C CG2 . THR C 1 20  ? -40.535 30.200  31.192  1.00 57.74  ? 20  THR C CG2 1 
ATOM   7009  N N   . ARG C 1 21  ? -40.780 32.513  34.571  1.00 57.95  ? 21  ARG C N   1 
ATOM   7010  C CA  . ARG C 1 21  ? -40.879 33.956  34.701  1.00 66.42  ? 21  ARG C CA  1 
ATOM   7011  C C   . ARG C 1 21  ? -39.627 34.487  35.411  1.00 62.54  ? 21  ARG C C   1 
ATOM   7012  O O   . ARG C 1 21  ? -38.963 35.398  34.926  1.00 62.12  ? 21  ARG C O   1 
ATOM   7013  C CB  . ARG C 1 21  ? -42.182 34.260  35.447  1.00 75.73  ? 21  ARG C CB  1 
ATOM   7014  C CG  . ARG C 1 21  ? -42.659 35.702  35.383  1.00 79.15  ? 21  ARG C CG  1 
ATOM   7015  C CD  . ARG C 1 21  ? -43.970 35.818  36.147  1.00 84.80  ? 21  ARG C CD  1 
ATOM   7016  N NE  . ARG C 1 21  ? -44.446 37.199  36.165  1.00 86.09  ? 21  ARG C NE  1 
ATOM   7017  C CZ  . ARG C 1 21  ? -44.661 37.911  37.266  1.00 81.05  ? 21  ARG C CZ  1 
ATOM   7018  N NH1 . ARG C 1 21  ? -45.121 37.314  38.353  1.00 73.04  ? 21  ARG C NH1 1 
ATOM   7019  N NH2 . ARG C 1 21  ? -44.421 39.212  37.257  1.00 75.66  ? 21  ARG C NH2 1 
ATOM   7020  N N   . LEU C 1 22  ? -39.275 33.883  36.550  1.00 55.80  ? 22  LEU C N   1 
ATOM   7021  C CA  . LEU C 1 22  ? -38.066 34.250  37.272  1.00 52.86  ? 22  LEU C CA  1 
ATOM   7022  C C   . LEU C 1 22  ? -36.857 34.273  36.341  1.00 52.44  ? 22  LEU C C   1 
ATOM   7023  O O   . LEU C 1 22  ? -36.000 35.123  36.483  1.00 57.07  ? 22  LEU C O   1 
ATOM   7024  C CB  . LEU C 1 22  ? -37.847 33.268  38.419  1.00 49.15  ? 22  LEU C CB  1 
ATOM   7025  C CG  . LEU C 1 22  ? -38.753 33.467  39.632  1.00 50.40  ? 22  LEU C CG  1 
ATOM   7026  C CD1 . LEU C 1 22  ? -38.632 32.301  40.588  1.00 54.55  ? 22  LEU C CD1 1 
ATOM   7027  C CD2 . LEU C 1 22  ? -38.428 34.749  40.377  1.00 57.44  ? 22  LEU C CD2 1 
ATOM   7028  N N   . LEU C 1 23  ? -36.771 33.335  35.401  1.00 61.24  ? 23  LEU C N   1 
ATOM   7029  C CA  . LEU C 1 23  ? -35.602 33.225  34.537  1.00 64.86  ? 23  LEU C CA  1 
ATOM   7030  C C   . LEU C 1 23  ? -35.613 34.304  33.462  1.00 63.41  ? 23  LEU C C   1 
ATOM   7031  O O   . LEU C 1 23  ? -34.590 34.948  33.254  1.00 58.54  ? 23  LEU C O   1 
ATOM   7032  C CB  . LEU C 1 23  ? -35.566 31.847  33.863  1.00 66.27  ? 23  LEU C CB  1 
ATOM   7033  C CG  . LEU C 1 23  ? -34.859 30.721  34.618  1.00 67.01  ? 23  LEU C CG  1 
ATOM   7034  C CD1 . LEU C 1 23  ? -34.492 29.602  33.646  1.00 61.58  ? 23  LEU C CD1 1 
ATOM   7035  C CD2 . LEU C 1 23  ? -33.619 31.232  35.356  1.00 68.07  ? 23  LEU C CD2 1 
ATOM   7036  N N   . LYS C 1 24  ? -36.751 34.443  32.769  1.00 68.61  ? 24  LYS C N   1 
ATOM   7037  C CA  . LYS C 1 24  ? -36.876 35.366  31.651  1.00 74.17  ? 24  LYS C CA  1 
ATOM   7038  C C   . LYS C 1 24  ? -36.888 36.828  32.113  1.00 71.59  ? 24  LYS C C   1 
ATOM   7039  O O   . LYS C 1 24  ? -36.231 37.669  31.501  1.00 59.52  ? 24  LYS C O   1 
ATOM   7040  C CB  . LYS C 1 24  ? -38.150 35.112  30.837  1.00 84.54  ? 24  LYS C CB  1 
ATOM   7041  C CG  . LYS C 1 24  ? -37.980 35.502  29.373  1.00 102.58 ? 24  LYS C CG  1 
ATOM   7042  C CD  . LYS C 1 24  ? -39.035 36.403  28.763  1.00 110.92 ? 24  LYS C CD  1 
ATOM   7043  C CE  . LYS C 1 24  ? -38.464 37.112  27.545  1.00 111.39 ? 24  LYS C CE  1 
ATOM   7044  N NZ  . LYS C 1 24  ? -39.297 38.309  27.193  1.00 121.31 ? 24  LYS C NZ  1 
ATOM   7045  N N   . GLU C 1 25  ? -37.607 37.127  33.207  1.00 69.12  ? 25  GLU C N   1 
ATOM   7046  C CA  . GLU C 1 25  ? -37.837 38.502  33.630  1.00 67.70  ? 25  GLU C CA  1 
ATOM   7047  C C   . GLU C 1 25  ? -36.904 38.943  34.767  1.00 65.86  ? 25  GLU C C   1 
ATOM   7048  O O   . GLU C 1 25  ? -36.828 40.139  35.049  1.00 71.45  ? 25  GLU C O   1 
ATOM   7049  C CB  . GLU C 1 25  ? -39.285 38.701  34.095  1.00 78.13  ? 25  GLU C CB  1 
ATOM   7050  C CG  . GLU C 1 25  ? -40.296 38.962  32.981  1.00 85.73  ? 25  GLU C CG  1 
ATOM   7051  C CD  . GLU C 1 25  ? -41.716 39.199  33.499  1.00 91.19  ? 25  GLU C CD  1 
ATOM   7052  O OE1 . GLU C 1 25  ? -41.900 40.130  34.320  1.00 81.24  ? 25  GLU C OE1 1 
ATOM   7053  O OE2 . GLU C 1 25  ? -42.641 38.444  33.103  1.00 84.58  ? 25  GLU C OE2 1 
ATOM   7054  N N   . PHE C 1 26  ? -36.231 38.024  35.474  1.00 56.08  ? 26  PHE C N   1 
ATOM   7055  C CA  . PHE C 1 26  ? -35.518 38.419  36.683  1.00 54.25  ? 26  PHE C CA  1 
ATOM   7056  C C   . PHE C 1 26  ? -34.174 37.695  36.840  1.00 50.18  ? 26  PHE C C   1 
ATOM   7057  O O   . PHE C 1 26  ? -33.608 37.629  37.940  1.00 48.03  ? 26  PHE C O   1 
ATOM   7058  C CB  . PHE C 1 26  ? -36.452 38.216  37.882  1.00 61.53  ? 26  PHE C CB  1 
ATOM   7059  C CG  . PHE C 1 26  ? -37.692 39.072  37.849  1.00 70.63  ? 26  PHE C CG  1 
ATOM   7060  C CD1 . PHE C 1 26  ? -37.639 40.415  38.204  1.00 78.16  ? 26  PHE C CD1 1 
ATOM   7061  C CD2 . PHE C 1 26  ? -38.903 38.549  37.415  1.00 78.46  ? 26  PHE C CD2 1 
ATOM   7062  C CE1 . PHE C 1 26  ? -38.777 41.203  38.157  1.00 77.49  ? 26  PHE C CE1 1 
ATOM   7063  C CE2 . PHE C 1 26  ? -40.041 39.341  37.357  1.00 81.14  ? 26  PHE C CE2 1 
ATOM   7064  C CZ  . PHE C 1 26  ? -39.976 40.665  37.734  1.00 85.41  ? 26  PHE C CZ  1 
ATOM   7065  N N   . GLY C 1 27  ? -33.629 37.215  35.719  1.00 50.59  ? 27  GLY C N   1 
ATOM   7066  C CA  . GLY C 1 27  ? -32.438 36.376  35.713  1.00 52.54  ? 27  GLY C CA  1 
ATOM   7067  C C   . GLY C 1 27  ? -31.183 37.067  36.249  1.00 55.32  ? 27  GLY C C   1 
ATOM   7068  O O   . GLY C 1 27  ? -30.280 36.378  36.711  1.00 57.22  ? 27  GLY C O   1 
ATOM   7069  N N   . ASN C 1 28  ? -31.102 38.411  36.155  1.00 57.59  ? 28  ASN C N   1 
ATOM   7070  C CA  . ASN C 1 28  ? -29.886 39.141  36.503  1.00 50.42  ? 28  ASN C CA  1 
ATOM   7071  C C   . ASN C 1 28  ? -29.997 39.759  37.893  1.00 46.84  ? 28  ASN C C   1 
ATOM   7072  O O   . ASN C 1 28  ? -29.028 40.340  38.389  1.00 46.35  ? 28  ASN C O   1 
ATOM   7073  C CB  . ASN C 1 28  ? -29.513 40.192  35.459  1.00 57.50  ? 28  ASN C CB  1 
ATOM   7074  C CG  . ASN C 1 28  ? -28.653 39.629  34.344  1.00 68.50  ? 28  ASN C CG  1 
ATOM   7075  O OD1 . ASN C 1 28  ? -29.136 38.821  33.559  1.00 79.20  ? 28  ASN C OD1 1 
ATOM   7076  N ND2 . ASN C 1 28  ? -27.396 40.045  34.254  1.00 77.63  ? 28  ASN C ND2 1 
ATOM   7077  N N   . VAL C 1 29  ? -31.138 39.583  38.567  1.00 43.07  ? 29  VAL C N   1 
ATOM   7078  C CA  . VAL C 1 29  ? -31.246 40.058  39.938  1.00 45.63  ? 29  VAL C CA  1 
ATOM   7079  C C   . VAL C 1 29  ? -30.199 39.362  40.809  1.00 49.08  ? 29  VAL C C   1 
ATOM   7080  O O   . VAL C 1 29  ? -30.195 38.133  40.869  1.00 51.93  ? 29  VAL C O   1 
ATOM   7081  C CB  . VAL C 1 29  ? -32.664 39.830  40.491  1.00 45.76  ? 29  VAL C CB  1 
ATOM   7082  C CG1 . VAL C 1 29  ? -32.739 40.080  41.999  1.00 44.26  ? 29  VAL C CG1 1 
ATOM   7083  C CG2 . VAL C 1 29  ? -33.701 40.659  39.730  1.00 44.53  ? 29  VAL C CG2 1 
ATOM   7084  N N   . LYS C 1 30  ? -29.321 40.145  41.456  1.00 46.64  ? 30  LYS C N   1 
ATOM   7085  C CA  . LYS C 1 30  ? -28.311 39.597  42.353  1.00 48.14  ? 30  LYS C CA  1 
ATOM   7086  C C   . LYS C 1 30  ? -28.972 39.129  43.652  1.00 48.26  ? 30  LYS C C   1 
ATOM   7087  O O   . LYS C 1 30  ? -29.960 39.728  44.050  1.00 42.05  ? 30  LYS C O   1 
ATOM   7088  C CB  . LYS C 1 30  ? -27.204 40.630  42.608  1.00 56.82  ? 30  LYS C CB  1 
ATOM   7089  C CG  . LYS C 1 30  ? -26.434 40.458  43.916  1.00 63.86  ? 30  LYS C CG  1 
ATOM   7090  C CD  . LYS C 1 30  ? -25.203 41.328  44.058  1.00 67.74  ? 30  LYS C CD  1 
ATOM   7091  C CE  . LYS C 1 30  ? -24.891 41.602  45.514  1.00 79.35  ? 30  LYS C CE  1 
ATOM   7092  N NZ  . LYS C 1 30  ? -23.467 41.964  45.708  1.00 84.30  ? 30  LYS C NZ  1 
ATOM   7093  N N   . ILE C 1 31  ? -28.444 38.049  44.280  1.00 55.56  ? 31  ILE C N   1 
ATOM   7094  C CA  . ILE C 1 31  ? -28.987 37.492  45.522  1.00 52.18  ? 31  ILE C CA  1 
ATOM   7095  C C   . ILE C 1 31  ? -27.885 37.162  46.530  1.00 48.96  ? 31  ILE C C   1 
ATOM   7096  O O   . ILE C 1 31  ? -28.189 36.957  47.711  1.00 42.60  ? 31  ILE C O   1 
ATOM   7097  C CB  . ILE C 1 31  ? -29.835 36.219  45.287  1.00 52.72  ? 31  ILE C CB  1 
ATOM   7098  C CG1 . ILE C 1 31  ? -29.000 35.041  44.755  1.00 51.71  ? 31  ILE C CG1 1 
ATOM   7099  C CG2 . ILE C 1 31  ? -31.039 36.512  44.401  1.00 53.01  ? 31  ILE C CG2 1 
ATOM   7100  C CD1 . ILE C 1 31  ? -29.719 33.705  44.770  1.00 46.60  ? 31  ILE C CD1 1 
ATOM   7101  N N   . ASP C 1 32  ? -26.639 36.995  46.074  1.00 47.66  ? 32  ASP C N   1 
ATOM   7102  C CA  . ASP C 1 32  ? -25.543 36.861  47.023  1.00 54.49  ? 32  ASP C CA  1 
ATOM   7103  C C   . ASP C 1 32  ? -24.227 37.185  46.316  1.00 50.35  ? 32  ASP C C   1 
ATOM   7104  O O   . ASP C 1 32  ? -24.201 37.450  45.118  1.00 39.71  ? 32  ASP C O   1 
ATOM   7105  C CB  . ASP C 1 32  ? -25.536 35.486  47.713  1.00 61.06  ? 32  ASP C CB  1 
ATOM   7106  C CG  . ASP C 1 32  ? -25.107 35.519  49.184  1.00 73.61  ? 32  ASP C CG  1 
ATOM   7107  O OD1 . ASP C 1 32  ? -24.596 36.592  49.640  1.00 69.16  ? 32  ASP C OD1 1 
ATOM   7108  O OD2 . ASP C 1 32  ? -25.292 34.478  49.888  1.00 67.37  ? 32  ASP C OD2 1 
ATOM   7109  N N   . GLU C 1 33  ? -23.148 37.209  47.101  1.00 53.41  ? 33  GLU C N   1 
ATOM   7110  C CA  . GLU C 1 33  ? -21.804 37.363  46.583  1.00 62.16  ? 33  GLU C CA  1 
ATOM   7111  C C   . GLU C 1 33  ? -20.894 36.327  47.242  1.00 60.26  ? 33  GLU C C   1 
ATOM   7112  O O   . GLU C 1 33  ? -21.149 35.862  48.350  1.00 67.29  ? 33  GLU C O   1 
ATOM   7113  C CB  . GLU C 1 33  ? -21.325 38.792  46.835  1.00 80.59  ? 33  GLU C CB  1 
ATOM   7114  C CG  . GLU C 1 33  ? -21.425 39.230  48.292  1.00 94.17  ? 33  GLU C CG  1 
ATOM   7115  C CD  . GLU C 1 33  ? -20.256 40.102  48.732  1.00 109.79 ? 33  GLU C CD  1 
ATOM   7116  O OE1 . GLU C 1 33  ? -20.215 41.281  48.297  1.00 113.71 ? 33  GLU C OE1 1 
ATOM   7117  O OE2 . GLU C 1 33  ? -19.360 39.595  49.477  1.00 97.04  ? 33  GLU C OE2 1 
ATOM   7118  N N   . VAL C 1 34  ? -19.803 35.994  46.547  1.00 60.56  ? 34  VAL C N   1 
ATOM   7119  C CA  . VAL C 1 34  ? -18.815 35.041  47.018  1.00 60.61  ? 34  VAL C CA  1 
ATOM   7120  C C   . VAL C 1 34  ? -17.581 35.811  47.478  1.00 58.52  ? 34  VAL C C   1 
ATOM   7121  O O   . VAL C 1 34  ? -17.030 36.617  46.728  1.00 57.67  ? 34  VAL C O   1 
ATOM   7122  C CB  . VAL C 1 34  ? -18.454 34.038  45.905  1.00 66.66  ? 34  VAL C CB  1 
ATOM   7123  C CG1 . VAL C 1 34  ? -17.730 32.812  46.446  1.00 64.75  ? 34  VAL C CG1 1 
ATOM   7124  C CG2 . VAL C 1 34  ? -19.680 33.612  45.107  1.00 66.26  ? 34  VAL C CG2 1 
ATOM   7125  N N   . THR C 1 35  ? -17.153 35.536  48.712  1.00 56.19  ? 35  THR C N   1 
ATOM   7126  C CA  . THR C 1 35  ? -15.872 36.003  49.215  1.00 53.02  ? 35  THR C CA  1 
ATOM   7127  C C   . THR C 1 35  ? -14.857 34.863  49.152  1.00 54.01  ? 35  THR C C   1 
ATOM   7128  O O   . THR C 1 35  ? -15.223 33.716  48.932  1.00 56.43  ? 35  THR C O   1 
ATOM   7129  C CB  . THR C 1 35  ? -16.004 36.533  50.647  1.00 53.66  ? 35  THR C CB  1 
ATOM   7130  O OG1 . THR C 1 35  ? -16.041 35.415  51.538  1.00 57.20  ? 35  THR C OG1 1 
ATOM   7131  C CG2 . THR C 1 35  ? -17.229 37.395  50.846  1.00 53.23  ? 35  THR C CG2 1 
ATOM   7132  N N   . ILE C 1 36  ? -13.584 35.186  49.390  1.00 55.43  ? 36  ILE C N   1 
ATOM   7133  C CA  . ILE C 1 36  ? -12.498 34.211  49.400  1.00 55.73  ? 36  ILE C CA  1 
ATOM   7134  C C   . ILE C 1 36  ? -12.725 33.168  50.506  1.00 49.21  ? 36  ILE C C   1 
ATOM   7135  O O   . ILE C 1 36  ? -12.669 31.978  50.255  1.00 48.56  ? 36  ILE C O   1 
ATOM   7136  C CB  . ILE C 1 36  ? -11.154 34.974  49.491  1.00 51.96  ? 36  ILE C CB  1 
ATOM   7137  C CG1 . ILE C 1 36  ? -10.835 35.607  48.131  1.00 52.99  ? 36  ILE C CG1 1 
ATOM   7138  C CG2 . ILE C 1 36  ? -10.014 34.102  50.000  1.00 48.81  ? 36  ILE C CG2 1 
ATOM   7139  C CD1 . ILE C 1 36  ? -9.471  36.241  48.019  1.00 50.88  ? 36  ILE C CD1 1 
ATOM   7140  N N   . SER C 1 37  ? -13.092 33.618  51.697  1.00 50.06  ? 37  SER C N   1 
ATOM   7141  C CA  . SER C 1 37  ? -13.376 32.692  52.820  1.00 50.14  ? 37  SER C CA  1 
ATOM   7142  C C   . SER C 1 37  ? -14.420 31.655  52.419  1.00 50.77  ? 37  SER C C   1 
ATOM   7143  O O   . SER C 1 37  ? -14.374 30.544  52.954  1.00 51.67  ? 37  SER C O   1 
ATOM   7144  C CB  . SER C 1 37  ? -13.857 33.456  54.007  1.00 52.69  ? 37  SER C CB  1 
ATOM   7145  O OG  . SER C 1 37  ? -14.777 34.462  53.620  1.00 67.54  ? 37  SER C OG  1 
ATOM   7146  N N   . GLN C 1 38  ? -15.330 32.017  51.526  1.00 50.20  ? 38  GLN C N   1 
ATOM   7147  C CA  . GLN C 1 38  ? -16.419 31.113  51.198  1.00 51.16  ? 38  GLN C CA  1 
ATOM   7148  C C   . GLN C 1 38  ? -15.998 30.099  50.129  1.00 53.55  ? 38  GLN C C   1 
ATOM   7149  O O   . GLN C 1 38  ? -16.474 28.972  50.152  1.00 61.56  ? 38  GLN C O   1 
ATOM   7150  C CB  . GLN C 1 38  ? -17.636 31.921  50.737  1.00 50.95  ? 38  GLN C CB  1 
ATOM   7151  C CG  . GLN C 1 38  ? -18.274 32.751  51.844  1.00 53.14  ? 38  GLN C CG  1 
ATOM   7152  C CD  . GLN C 1 38  ? -19.452 33.528  51.310  1.00 55.86  ? 38  GLN C CD  1 
ATOM   7153  O OE1 . GLN C 1 38  ? -19.320 34.355  50.403  1.00 57.53  ? 38  GLN C OE1 1 
ATOM   7154  N NE2 . GLN C 1 38  ? -20.626 33.233  51.845  1.00 54.49  ? 38  GLN C NE2 1 
ATOM   7155  N N   . ALA C 1 39  ? -15.159 30.499  49.165  1.00 48.66  ? 39  ALA C N   1 
ATOM   7156  C CA  . ALA C 1 39  ? -14.648 29.587  48.149  1.00 51.75  ? 39  ALA C CA  1 
ATOM   7157  C C   . ALA C 1 39  ? -13.689 28.542  48.748  1.00 55.36  ? 39  ALA C C   1 
ATOM   7158  O O   . ALA C 1 39  ? -13.688 27.384  48.326  1.00 54.80  ? 39  ALA C O   1 
ATOM   7159  C CB  . ALA C 1 39  ? -13.972 30.381  47.053  1.00 52.67  ? 39  ALA C CB  1 
ATOM   7160  N N   . ILE C 1 40  ? -12.867 28.957  49.721  1.00 53.07  ? 40  ILE C N   1 
ATOM   7161  C CA  . ILE C 1 40  ? -11.933 28.075  50.403  1.00 55.13  ? 40  ILE C CA  1 
ATOM   7162  C C   . ILE C 1 40  ? -12.657 27.236  51.456  1.00 55.32  ? 40  ILE C C   1 
ATOM   7163  O O   . ILE C 1 40  ? -12.221 26.134  51.785  1.00 68.46  ? 40  ILE C O   1 
ATOM   7164  C CB  . ILE C 1 40  ? -10.803 28.916  51.033  1.00 58.08  ? 40  ILE C CB  1 
ATOM   7165  C CG1 . ILE C 1 40  ? -9.904  29.512  49.943  1.00 64.77  ? 40  ILE C CG1 1 
ATOM   7166  C CG2 . ILE C 1 40  ? -10.008 28.111  52.052  1.00 51.97  ? 40  ILE C CG2 1 
ATOM   7167  C CD1 . ILE C 1 40  ? -8.793  30.411  50.459  1.00 64.57  ? 40  ILE C CD1 1 
ATOM   7168  N N   . GLY C 1 41  ? -13.750 27.781  52.004  1.00 54.38  ? 41  GLY C N   1 
ATOM   7169  C CA  . GLY C 1 41  ? -14.448 27.168  53.121  1.00 51.92  ? 41  GLY C CA  1 
ATOM   7170  C C   . GLY C 1 41  ? -15.740 26.478  52.693  1.00 55.16  ? 41  GLY C C   1 
ATOM   7171  O O   . GLY C 1 41  ? -16.729 26.517  53.414  1.00 58.19  ? 41  GLY C O   1 
ATOM   7172  N N   . GLY C 1 42  ? -15.721 25.826  51.522  1.00 62.79  ? 42  GLY C N   1 
ATOM   7173  C CA  . GLY C 1 42  ? -16.784 24.918  51.118  1.00 61.45  ? 42  GLY C CA  1 
ATOM   7174  C C   . GLY C 1 42  ? -18.108 25.647  50.926  1.00 53.29  ? 42  GLY C C   1 
ATOM   7175  O O   . GLY C 1 42  ? -19.124 25.252  51.498  1.00 57.40  ? 42  GLY C O   1 
ATOM   7176  N N   . MET C 1 43  ? -18.042 26.738  50.152  1.00 50.81  ? 43  MET C N   1 
ATOM   7177  C CA  . MET C 1 43  ? -19.188 27.526  49.746  1.00 49.82  ? 43  MET C CA  1 
ATOM   7178  C C   . MET C 1 43  ? -20.062 27.935  50.938  1.00 51.22  ? 43  MET C C   1 
ATOM   7179  O O   . MET C 1 43  ? -21.246 28.198  50.759  1.00 48.33  ? 43  MET C O   1 
ATOM   7180  C CB  . MET C 1 43  ? -20.048 26.697  48.793  1.00 55.35  ? 43  MET C CB  1 
ATOM   7181  C CG  . MET C 1 43  ? -19.395 26.323  47.481  1.00 51.93  ? 43  MET C CG  1 
ATOM   7182  S SD  . MET C 1 43  ? -20.587 25.236  46.565  1.00 53.58  ? 43  MET C SD  1 
ATOM   7183  C CE  . MET C 1 43  ? -19.616 24.857  45.095  1.00 47.63  ? 43  MET C CE  1 
ATOM   7184  N N   . ARG C 1 44  ? -19.511 28.022  52.154  1.00 56.85  ? 44  ARG C N   1 
ATOM   7185  C CA  . ARG C 1 44  ? -20.363 28.138  53.332  1.00 62.78  ? 44  ARG C CA  1 
ATOM   7186  C C   . ARG C 1 44  ? -21.131 29.446  53.269  1.00 56.57  ? 44  ARG C C   1 
ATOM   7187  O O   . ARG C 1 44  ? -20.527 30.506  53.132  1.00 65.36  ? 44  ARG C O   1 
ATOM   7188  C CB  . ARG C 1 44  ? -19.533 28.087  54.609  1.00 77.27  ? 44  ARG C CB  1 
ATOM   7189  C CG  . ARG C 1 44  ? -20.299 28.041  55.928  1.00 88.72  ? 44  ARG C CG  1 
ATOM   7190  C CD  . ARG C 1 44  ? -19.265 27.949  57.053  1.00 107.47 ? 44  ARG C CD  1 
ATOM   7191  N NE  . ARG C 1 44  ? -18.167 28.934  56.911  1.00 125.56 ? 44  ARG C NE  1 
ATOM   7192  C CZ  . ARG C 1 44  ? -16.904 28.681  56.520  1.00 112.39 ? 44  ARG C CZ  1 
ATOM   7193  N NH1 . ARG C 1 44  ? -16.300 27.549  56.846  1.00 91.60  ? 44  ARG C NH1 1 
ATOM   7194  N NH2 . ARG C 1 44  ? -16.234 29.580  55.811  1.00 104.32 ? 44  ARG C NH2 1 
ATOM   7195  N N   . GLY C 1 45  ? -22.459 29.344  53.323  1.00 57.21  ? 45  GLY C N   1 
ATOM   7196  C CA  . GLY C 1 45  ? -23.333 30.506  53.345  1.00 55.86  ? 45  GLY C CA  1 
ATOM   7197  C C   . GLY C 1 45  ? -23.839 30.934  51.966  1.00 50.93  ? 45  GLY C C   1 
ATOM   7198  O O   . GLY C 1 45  ? -24.757 31.749  51.908  1.00 56.29  ? 45  GLY C O   1 
ATOM   7199  N N   . ILE C 1 46  ? -23.271 30.400  50.870  1.00 50.71  ? 46  ILE C N   1 
ATOM   7200  C CA  . ILE C 1 46  ? -23.617 30.900  49.547  1.00 48.94  ? 46  ILE C CA  1 
ATOM   7201  C C   . ILE C 1 46  ? -24.998 30.386  49.157  1.00 49.92  ? 46  ILE C C   1 
ATOM   7202  O O   . ILE C 1 46  ? -25.232 29.177  49.170  1.00 45.13  ? 46  ILE C O   1 
ATOM   7203  C CB  . ILE C 1 46  ? -22.626 30.486  48.448  1.00 48.46  ? 46  ILE C CB  1 
ATOM   7204  C CG1 . ILE C 1 46  ? -21.199 30.962  48.714  1.00 52.26  ? 46  ILE C CG1 1 
ATOM   7205  C CG2 . ILE C 1 46  ? -23.129 30.965  47.088  1.00 46.80  ? 46  ILE C CG2 1 
ATOM   7206  C CD1 . ILE C 1 46  ? -20.174 30.364  47.732  1.00 52.31  ? 46  ILE C CD1 1 
ATOM   7207  N N   . LYS C 1 47  ? -25.869 31.323  48.746  1.00 50.92  ? 47  LYS C N   1 
ATOM   7208  C CA  . LYS C 1 47  ? -27.224 31.018  48.324  1.00 53.90  ? 47  LYS C CA  1 
ATOM   7209  C C   . LYS C 1 47  ? -27.173 30.682  46.846  1.00 50.74  ? 47  LYS C C   1 
ATOM   7210  O O   . LYS C 1 47  ? -27.266 31.592  46.027  1.00 48.76  ? 47  LYS C O   1 
ATOM   7211  C CB  . LYS C 1 47  ? -28.172 32.182  48.641  1.00 53.99  ? 47  LYS C CB  1 
ATOM   7212  C CG  . LYS C 1 47  ? -28.542 32.272  50.117  1.00 60.64  ? 47  LYS C CG  1 
ATOM   7213  C CD  . LYS C 1 47  ? -28.817 33.677  50.630  1.00 65.85  ? 47  LYS C CD  1 
ATOM   7214  C CE  . LYS C 1 47  ? -28.447 33.843  52.090  1.00 72.73  ? 47  LYS C CE  1 
ATOM   7215  N NZ  . LYS C 1 47  ? -29.110 35.029  52.678  1.00 78.57  ? 47  LYS C NZ  1 
ATOM   7216  N N   . SER C 1 48  ? -27.040 29.377  46.555  1.00 49.15  ? 48  SER C N   1 
ATOM   7217  C CA  . SER C 1 48  ? -26.668 28.886  45.230  1.00 52.31  ? 48  SER C CA  1 
ATOM   7218  C C   . SER C 1 48  ? -27.541 27.711  44.766  1.00 45.92  ? 48  SER C C   1 
ATOM   7219  O O   . SER C 1 48  ? -27.383 27.208  43.650  1.00 51.69  ? 48  SER C O   1 
ATOM   7220  C CB  . SER C 1 48  ? -25.184 28.526  45.213  1.00 59.10  ? 48  SER C CB  1 
ATOM   7221  O OG  . SER C 1 48  ? -24.788 27.849  46.419  1.00 60.88  ? 48  SER C OG  1 
ATOM   7222  N N   . LEU C 1 49  ? -28.495 27.298  45.610  1.00 50.19  ? 49  LEU C N   1 
ATOM   7223  C CA  . LEU C 1 49  ? -29.375 26.172  45.338  1.00 50.82  ? 49  LEU C CA  1 
ATOM   7224  C C   . LEU C 1 49  ? -30.833 26.591  45.503  1.00 52.42  ? 49  LEU C C   1 
ATOM   7225  O O   . LEU C 1 49  ? -31.150 27.333  46.437  1.00 57.64  ? 49  LEU C O   1 
ATOM   7226  C CB  . LEU C 1 49  ? -29.031 25.075  46.351  1.00 48.55  ? 49  LEU C CB  1 
ATOM   7227  C CG  . LEU C 1 49  ? -27.712 24.350  46.090  1.00 53.33  ? 49  LEU C CG  1 
ATOM   7228  C CD1 . LEU C 1 49  ? -27.349 23.488  47.271  1.00 54.23  ? 49  LEU C CD1 1 
ATOM   7229  C CD2 . LEU C 1 49  ? -27.763 23.507  44.806  1.00 50.15  ? 49  LEU C CD2 1 
ATOM   7230  N N   . VAL C 1 50  ? -31.712 26.035  44.658  1.00 52.05  ? 50  VAL C N   1 
ATOM   7231  C CA  . VAL C 1 50  ? -33.151 26.234  44.791  1.00 57.80  ? 50  VAL C CA  1 
ATOM   7232  C C   . VAL C 1 50  ? -33.861 24.895  45.058  1.00 53.78  ? 50  VAL C C   1 
ATOM   7233  O O   . VAL C 1 50  ? -33.750 23.967  44.257  1.00 48.32  ? 50  VAL C O   1 
ATOM   7234  C CB  . VAL C 1 50  ? -33.719 26.949  43.547  1.00 56.36  ? 50  VAL C CB  1 
ATOM   7235  C CG1 . VAL C 1 50  ? -35.052 27.602  43.847  1.00 59.44  ? 50  VAL C CG1 1 
ATOM   7236  C CG2 . VAL C 1 50  ? -32.762 28.001  43.012  1.00 56.01  ? 50  VAL C CG2 1 
ATOM   7237  N N   . THR C 1 51  ? -34.604 24.818  46.179  1.00 51.43  ? 51  THR C N   1 
ATOM   7238  C CA  . THR C 1 51  ? -35.424 23.675  46.576  1.00 61.41  ? 51  THR C CA  1 
ATOM   7239  C C   . THR C 1 51  ? -36.709 24.175  47.237  1.00 55.66  ? 51  THR C C   1 
ATOM   7240  O O   . THR C 1 51  ? -36.663 25.139  47.997  1.00 48.38  ? 51  THR C O   1 
ATOM   7241  C CB  . THR C 1 51  ? -34.731 22.760  47.615  1.00 74.34  ? 51  THR C CB  1 
ATOM   7242  O OG1 . THR C 1 51  ? -35.548 21.618  47.940  1.00 77.78  ? 51  THR C OG1 1 
ATOM   7243  C CG2 . THR C 1 51  ? -34.403 23.469  48.919  1.00 71.02  ? 51  THR C CG2 1 
ATOM   7244  N N   . ASP C 1 52  ? -37.835 23.471  47.000  1.00 61.32  ? 52  ASP C N   1 
ATOM   7245  C CA  . ASP C 1 52  ? -39.137 23.850  47.550  1.00 58.28  ? 52  ASP C CA  1 
ATOM   7246  C C   . ASP C 1 52  ? -39.628 22.816  48.569  1.00 54.04  ? 52  ASP C C   1 
ATOM   7247  O O   . ASP C 1 52  ? -40.596 23.065  49.295  1.00 55.56  ? 52  ASP C O   1 
ATOM   7248  C CB  . ASP C 1 52  ? -40.120 24.138  46.408  1.00 61.43  ? 52  ASP C CB  1 
ATOM   7249  C CG  . ASP C 1 52  ? -39.600 25.259  45.505  1.00 63.49  ? 52  ASP C CG  1 
ATOM   7250  O OD1 . ASP C 1 52  ? -39.620 26.420  45.965  1.00 59.11  ? 52  ASP C OD1 1 
ATOM   7251  O OD2 . ASP C 1 52  ? -39.095 24.960  44.371  1.00 66.59  ? 52  ASP C OD2 1 
ATOM   7252  N N   . ILE C 1 53  ? -38.903 21.695  48.700  1.00 45.33  ? 53  ILE C N   1 
ATOM   7253  C CA  . ILE C 1 53  ? -39.341 20.609  49.559  1.00 42.49  ? 53  ILE C CA  1 
ATOM   7254  C C   . ILE C 1 53  ? -39.233 21.042  51.021  1.00 37.00  ? 53  ILE C C   1 
ATOM   7255  O O   . ILE C 1 53  ? -40.103 20.726  51.832  1.00 33.01  ? 53  ILE C O   1 
ATOM   7256  C CB  . ILE C 1 53  ? -38.558 19.307  49.288  1.00 44.59  ? 53  ILE C CB  1 
ATOM   7257  C CG1 . ILE C 1 53  ? -38.502 18.949  47.805  1.00 49.95  ? 53  ILE C CG1 1 
ATOM   7258  C CG2 . ILE C 1 53  ? -39.165 18.162  50.083  1.00 47.52  ? 53  ILE C CG2 1 
ATOM   7259  C CD1 . ILE C 1 53  ? -39.827 18.526  47.226  1.00 50.90  ? 53  ILE C CD1 1 
ATOM   7260  N N   . SER C 1 54  ? -38.157 21.741  51.373  1.00 34.15  ? 54  SER C N   1 
ATOM   7261  C CA  . SER C 1 54  ? -37.983 22.150  52.759  1.00 39.13  ? 54  SER C CA  1 
ATOM   7262  C C   . SER C 1 54  ? -37.086 23.374  52.807  1.00 40.43  ? 54  SER C C   1 
ATOM   7263  O O   . SER C 1 54  ? -36.351 23.668  51.844  1.00 36.51  ? 54  SER C O   1 
ATOM   7264  C CB  . SER C 1 54  ? -37.454 21.021  53.669  1.00 46.22  ? 54  SER C CB  1 
ATOM   7265  O OG  . SER C 1 54  ? -36.082 20.702  53.424  1.00 43.95  ? 54  SER C OG  1 
ATOM   7266  N N   . TYR C 1 55  ? -37.224 24.110  53.916  1.00 41.07  ? 55  TYR C N   1 
ATOM   7267  C CA  . TYR C 1 55  ? -36.420 25.303  54.118  1.00 50.35  ? 55  TYR C CA  1 
ATOM   7268  C C   . TYR C 1 55  ? -35.946 25.301  55.560  1.00 52.81  ? 55  TYR C C   1 
ATOM   7269  O O   . TYR C 1 55  ? -36.727 25.038  56.473  1.00 49.06  ? 55  TYR C O   1 
ATOM   7270  C CB  . TYR C 1 55  ? -37.148 26.618  53.803  1.00 53.24  ? 55  TYR C CB  1 
ATOM   7271  C CG  . TYR C 1 55  ? -36.236 27.810  53.959  1.00 66.31  ? 55  TYR C CG  1 
ATOM   7272  C CD1 . TYR C 1 55  ? -35.142 27.971  53.114  1.00 73.03  ? 55  TYR C CD1 1 
ATOM   7273  C CD2 . TYR C 1 55  ? -36.395 28.729  54.995  1.00 66.32  ? 55  TYR C CD2 1 
ATOM   7274  C CE1 . TYR C 1 55  ? -34.257 29.034  53.266  1.00 75.67  ? 55  TYR C CE1 1 
ATOM   7275  C CE2 . TYR C 1 55  ? -35.518 29.797  55.155  1.00 63.80  ? 55  TYR C CE2 1 
ATOM   7276  C CZ  . TYR C 1 55  ? -34.443 29.952  54.290  1.00 68.62  ? 55  TYR C CZ  1 
ATOM   7277  O OH  . TYR C 1 55  ? -33.550 30.992  54.418  1.00 61.93  ? 55  TYR C OH  1 
ATOM   7278  N N   . LEU C 1 56  ? -34.643 25.553  55.713  1.00 61.76  ? 56  LEU C N   1 
ATOM   7279  C CA  . LEU C 1 56  ? -34.011 25.660  57.010  1.00 67.02  ? 56  LEU C CA  1 
ATOM   7280  C C   . LEU C 1 56  ? -33.797 27.140  57.299  1.00 67.15  ? 56  LEU C C   1 
ATOM   7281  O O   . LEU C 1 56  ? -32.973 27.798  56.661  1.00 58.02  ? 56  LEU C O   1 
ATOM   7282  C CB  . LEU C 1 56  ? -32.694 24.876  56.977  1.00 74.77  ? 56  LEU C CB  1 
ATOM   7283  C CG  . LEU C 1 56  ? -31.851 24.943  58.249  1.00 79.16  ? 56  LEU C CG  1 
ATOM   7284  C CD1 . LEU C 1 56  ? -32.656 24.475  59.451  1.00 77.41  ? 56  LEU C CD1 1 
ATOM   7285  C CD2 . LEU C 1 56  ? -30.566 24.126  58.085  1.00 84.81  ? 56  LEU C CD2 1 
ATOM   7286  N N   . ASP C 1 57  ? -34.623 27.663  58.212  1.00 78.42  ? 57  ASP C N   1 
ATOM   7287  C CA  . ASP C 1 57  ? -34.417 28.970  58.809  1.00 80.08  ? 57  ASP C CA  1 
ATOM   7288  C C   . ASP C 1 57  ? -33.380 28.766  59.915  1.00 86.04  ? 57  ASP C C   1 
ATOM   7289  O O   . ASP C 1 57  ? -33.575 27.852  60.726  1.00 90.15  ? 57  ASP C O   1 
ATOM   7290  C CB  . ASP C 1 57  ? -35.764 29.523  59.303  1.00 73.81  ? 57  ASP C CB  1 
ATOM   7291  C CG  . ASP C 1 57  ? -35.664 30.826  60.080  1.00 70.11  ? 57  ASP C CG  1 
ATOM   7292  O OD1 . ASP C 1 57  ? -35.177 31.811  59.497  1.00 67.62  ? 57  ASP C OD1 1 
ATOM   7293  O OD2 . ASP C 1 57  ? -36.046 30.841  61.265  1.00 63.61  ? 57  ASP C OD2 1 
ATOM   7294  N N   . PRO C 1 58  ? -32.243 29.526  59.980  1.00 82.16  ? 58  PRO C N   1 
ATOM   7295  C CA  . PRO C 1 58  ? -31.288 29.383  61.102  1.00 76.54  ? 58  PRO C CA  1 
ATOM   7296  C C   . PRO C 1 58  ? -31.875 29.411  62.529  1.00 68.62  ? 58  PRO C C   1 
ATOM   7297  O O   . PRO C 1 58  ? -31.275 28.858  63.456  1.00 60.07  ? 58  PRO C O   1 
ATOM   7298  C CB  . PRO C 1 58  ? -30.290 30.532  60.850  1.00 69.99  ? 58  PRO C CB  1 
ATOM   7299  C CG  . PRO C 1 58  ? -30.308 30.717  59.342  1.00 67.11  ? 58  PRO C CG  1 
ATOM   7300  C CD  . PRO C 1 58  ? -31.751 30.453  58.937  1.00 69.61  ? 58  PRO C CD  1 
ATOM   7301  N N   . GLU C 1 59  ? -33.093 29.962  62.674  1.00 70.84  ? 59  GLU C N   1 
ATOM   7302  C CA  . GLU C 1 59  ? -33.696 30.277  63.959  1.00 78.48  ? 59  GLU C CA  1 
ATOM   7303  C C   . GLU C 1 59  ? -34.847 29.325  64.305  1.00 73.32  ? 59  GLU C C   1 
ATOM   7304  O O   . GLU C 1 59  ? -34.769 28.623  65.306  1.00 71.63  ? 59  GLU C O   1 
ATOM   7305  C CB  . GLU C 1 59  ? -34.174 31.730  63.949  1.00 88.36  ? 59  GLU C CB  1 
ATOM   7306  C CG  . GLU C 1 59  ? -33.084 32.754  63.668  1.00 96.91  ? 59  GLU C CG  1 
ATOM   7307  C CD  . GLU C 1 59  ? -32.181 33.118  64.840  1.00 101.88 ? 59  GLU C CD  1 
ATOM   7308  O OE1 . GLU C 1 59  ? -32.713 33.500  65.927  1.00 112.31 ? 59  GLU C OE1 1 
ATOM   7309  O OE2 . GLU C 1 59  ? -30.946 33.020  64.658  1.00 98.71  ? 59  GLU C OE2 1 
ATOM   7310  N N   . GLU C 1 60  ? -35.935 29.320  63.519  1.00 77.60  ? 60  GLU C N   1 
ATOM   7311  C CA  . GLU C 1 60  ? -37.118 28.518  63.838  1.00 80.00  ? 60  GLU C CA  1 
ATOM   7312  C C   . GLU C 1 60  ? -36.842 27.024  63.615  1.00 71.26  ? 60  GLU C C   1 
ATOM   7313  O O   . GLU C 1 60  ? -37.435 26.166  64.282  1.00 56.49  ? 60  GLU C O   1 
ATOM   7314  C CB  . GLU C 1 60  ? -38.339 28.906  62.996  1.00 91.90  ? 60  GLU C CB  1 
ATOM   7315  C CG  . GLU C 1 60  ? -38.656 30.399  62.944  1.00 106.92 ? 60  GLU C CG  1 
ATOM   7316  C CD  . GLU C 1 60  ? -38.594 31.180  64.245  1.00 109.37 ? 60  GLU C CD  1 
ATOM   7317  O OE1 . GLU C 1 60  ? -39.077 30.662  65.273  1.00 113.31 ? 60  GLU C OE1 1 
ATOM   7318  O OE2 . GLU C 1 60  ? -38.093 32.322  64.209  1.00 103.12 ? 60  GLU C OE2 1 
ATOM   7319  N N   . GLY C 1 61  ? -35.960 26.736  62.644  1.00 60.41  ? 61  GLY C N   1 
ATOM   7320  C CA  . GLY C 1 61  ? -35.585 25.387  62.260  1.00 60.68  ? 61  GLY C CA  1 
ATOM   7321  C C   . GLY C 1 61  ? -36.097 25.017  60.861  1.00 58.25  ? 61  GLY C C   1 
ATOM   7322  O O   . GLY C 1 61  ? -36.245 25.865  59.970  1.00 58.52  ? 61  GLY C O   1 
ATOM   7323  N N   . ILE C 1 62  ? -36.362 23.717  60.695  1.00 53.05  ? 62  ILE C N   1 
ATOM   7324  C CA  . ILE C 1 62  ? -36.781 23.144  59.424  1.00 50.19  ? 62  ILE C CA  1 
ATOM   7325  C C   . ILE C 1 62  ? -38.306 23.260  59.297  1.00 44.19  ? 62  ILE C C   1 
ATOM   7326  O O   . ILE C 1 62  ? -39.053 23.105  60.278  1.00 41.05  ? 62  ILE C O   1 
ATOM   7327  C CB  . ILE C 1 62  ? -36.227 21.700  59.255  1.00 44.68  ? 62  ILE C CB  1 
ATOM   7328  C CG1 . ILE C 1 62  ? -36.467 21.125  57.853  1.00 41.44  ? 62  ILE C CG1 1 
ATOM   7329  C CG2 . ILE C 1 62  ? -36.732 20.752  60.337  1.00 47.65  ? 62  ILE C CG2 1 
ATOM   7330  C CD1 . ILE C 1 62  ? -35.630 21.773  56.755  1.00 38.01  ? 62  ILE C CD1 1 
ATOM   7331  N N   . ARG C 1 63  ? -38.731 23.612  58.072  1.00 42.24  ? 63  ARG C N   1 
ATOM   7332  C CA  . ARG C 1 63  ? -40.117 23.548  57.656  1.00 46.36  ? 63  ARG C CA  1 
ATOM   7333  C C   . ARG C 1 63  ? -40.183 22.610  56.465  1.00 38.62  ? 63  ARG C C   1 
ATOM   7334  O O   . ARG C 1 63  ? -39.435 22.799  55.514  1.00 40.99  ? 63  ARG C O   1 
ATOM   7335  C CB  . ARG C 1 63  ? -40.659 24.914  57.206  1.00 53.11  ? 63  ARG C CB  1 
ATOM   7336  C CG  . ARG C 1 63  ? -40.934 25.913  58.325  1.00 59.17  ? 63  ARG C CG  1 
ATOM   7337  C CD  . ARG C 1 63  ? -41.867 27.025  57.872  1.00 66.76  ? 63  ARG C CD  1 
ATOM   7338  N NE  . ARG C 1 63  ? -41.694 28.260  58.621  1.00 85.21  ? 63  ARG C NE  1 
ATOM   7339  C CZ  . ARG C 1 63  ? -41.801 28.381  59.947  1.00 101.98 ? 63  ARG C CZ  1 
ATOM   7340  N NH1 . ARG C 1 63  ? -42.847 27.892  60.604  1.00 90.44  ? 63  ARG C NH1 1 
ATOM   7341  N NH2 . ARG C 1 63  ? -40.865 29.049  60.605  1.00 101.31 ? 63  ARG C NH2 1 
ATOM   7342  N N   . PHE C 1 64  ? -41.100 21.635  56.521  1.00 41.69  ? 64  PHE C N   1 
ATOM   7343  C CA  . PHE C 1 64  ? -41.377 20.764  55.388  1.00 43.78  ? 64  PHE C CA  1 
ATOM   7344  C C   . PHE C 1 64  ? -42.561 21.317  54.607  1.00 41.02  ? 64  PHE C C   1 
ATOM   7345  O O   . PHE C 1 64  ? -43.669 21.293  55.109  1.00 48.27  ? 64  PHE C O   1 
ATOM   7346  C CB  . PHE C 1 64  ? -41.692 19.348  55.867  1.00 47.76  ? 64  PHE C CB  1 
ATOM   7347  C CG  . PHE C 1 64  ? -40.615 18.743  56.729  1.00 53.38  ? 64  PHE C CG  1 
ATOM   7348  C CD1 . PHE C 1 64  ? -39.324 18.583  56.242  1.00 56.50  ? 64  PHE C CD1 1 
ATOM   7349  C CD2 . PHE C 1 64  ? -40.873 18.380  58.043  1.00 54.88  ? 64  PHE C CD2 1 
ATOM   7350  C CE1 . PHE C 1 64  ? -38.334 18.028  57.039  1.00 55.97  ? 64  PHE C CE1 1 
ATOM   7351  C CE2 . PHE C 1 64  ? -39.875 17.824  58.832  1.00 55.47  ? 64  PHE C CE2 1 
ATOM   7352  C CZ  . PHE C 1 64  ? -38.606 17.654  58.329  1.00 52.47  ? 64  PHE C CZ  1 
ATOM   7353  N N   . ARG C 1 65  ? -42.315 21.821  53.398  1.00 39.52  ? 65  ARG C N   1 
ATOM   7354  C CA  . ARG C 1 65  ? -43.361 22.397  52.563  1.00 42.61  ? 65  ARG C CA  1 
ATOM   7355  C C   . ARG C 1 65  ? -44.145 23.478  53.326  1.00 48.19  ? 65  ARG C C   1 
ATOM   7356  O O   . ARG C 1 65  ? -45.370 23.548  53.216  1.00 50.60  ? 65  ARG C O   1 
ATOM   7357  C CB  . ARG C 1 65  ? -44.285 21.277  52.066  1.00 39.45  ? 65  ARG C CB  1 
ATOM   7358  C CG  . ARG C 1 65  ? -43.688 20.380  50.989  1.00 37.93  ? 65  ARG C CG  1 
ATOM   7359  C CD  . ARG C 1 65  ? -43.537 21.123  49.683  1.00 38.06  ? 65  ARG C CD  1 
ATOM   7360  N NE  . ARG C 1 65  ? -43.220 20.208  48.608  1.00 39.38  ? 65  ARG C NE  1 
ATOM   7361  C CZ  . ARG C 1 65  ? -43.107 20.543  47.320  1.00 41.57  ? 65  ARG C CZ  1 
ATOM   7362  N NH1 . ARG C 1 65  ? -42.979 21.807  46.951  1.00 38.03  ? 65  ARG C NH1 1 
ATOM   7363  N NH2 . ARG C 1 65  ? -43.094 19.592  46.399  1.00 41.08  ? 65  ARG C NH2 1 
ATOM   7364  N N   . GLY C 1 66  ? -43.449 24.290  54.135  1.00 45.23  ? 66  GLY C N   1 
ATOM   7365  C CA  . GLY C 1 66  ? -44.090 25.361  54.874  1.00 44.84  ? 66  GLY C CA  1 
ATOM   7366  C C   . GLY C 1 66  ? -44.523 24.976  56.293  1.00 46.84  ? 66  GLY C C   1 
ATOM   7367  O O   . GLY C 1 66  ? -44.725 25.854  57.124  1.00 51.98  ? 66  GLY C O   1 
ATOM   7368  N N   . TYR C 1 67  ? -44.661 23.687  56.602  1.00 44.88  ? 67  TYR C N   1 
ATOM   7369  C CA  . TYR C 1 67  ? -45.119 23.288  57.930  1.00 47.45  ? 67  TYR C CA  1 
ATOM   7370  C C   . TYR C 1 67  ? -43.950 23.038  58.886  1.00 46.39  ? 67  TYR C C   1 
ATOM   7371  O O   . TYR C 1 67  ? -42.942 22.445  58.515  1.00 48.42  ? 67  TYR C O   1 
ATOM   7372  C CB  . TYR C 1 67  ? -45.947 22.003  57.850  1.00 50.65  ? 67  TYR C CB  1 
ATOM   7373  C CG  . TYR C 1 67  ? -47.180 22.102  56.991  1.00 56.36  ? 67  TYR C CG  1 
ATOM   7374  C CD1 . TYR C 1 67  ? -48.374 22.574  57.513  1.00 56.40  ? 67  TYR C CD1 1 
ATOM   7375  C CD2 . TYR C 1 67  ? -47.143 21.773  55.644  1.00 61.64  ? 67  TYR C CD2 1 
ATOM   7376  C CE1 . TYR C 1 67  ? -49.514 22.663  56.728  1.00 57.40  ? 67  TYR C CE1 1 
ATOM   7377  C CE2 . TYR C 1 67  ? -48.273 21.859  54.842  1.00 66.32  ? 67  TYR C CE2 1 
ATOM   7378  C CZ  . TYR C 1 67  ? -49.467 22.298  55.396  1.00 59.80  ? 67  TYR C CZ  1 
ATOM   7379  O OH  . TYR C 1 67  ? -50.598 22.425  54.644  1.00 53.77  ? 67  TYR C OH  1 
ATOM   7380  N N   . THR C 1 68  ? -44.128 23.440  60.153  1.00 51.63  ? 68  THR C N   1 
ATOM   7381  C CA  . THR C 1 68  ? -43.219 23.054  61.220  1.00 45.66  ? 68  THR C CA  1 
ATOM   7382  C C   . THR C 1 68  ? -43.422 21.571  61.532  1.00 49.13  ? 68  THR C C   1 
ATOM   7383  O O   . THR C 1 68  ? -44.401 20.936  61.139  1.00 43.53  ? 68  THR C O   1 
ATOM   7384  C CB  . THR C 1 68  ? -43.403 23.880  62.507  1.00 45.19  ? 68  THR C CB  1 
ATOM   7385  O OG1 . THR C 1 68  ? -44.590 23.481  63.192  1.00 40.34  ? 68  THR C OG1 1 
ATOM   7386  C CG2 . THR C 1 68  ? -43.444 25.376  62.274  1.00 44.32  ? 68  THR C CG2 1 
ATOM   7387  N N   . ILE C 1 69  ? -42.469 21.023  62.273  1.00 50.51  ? 69  ILE C N   1 
ATOM   7388  C CA  . ILE C 1 69  ? -42.504 19.622  62.614  1.00 48.00  ? 69  ILE C CA  1 
ATOM   7389  C C   . ILE C 1 69  ? -43.731 19.369  63.481  1.00 52.67  ? 69  ILE C C   1 
ATOM   7390  O O   . ILE C 1 69  ? -44.503 18.454  63.178  1.00 57.81  ? 69  ILE C O   1 
ATOM   7391  C CB  . ILE C 1 69  ? -41.160 19.219  63.254  1.00 53.31  ? 69  ILE C CB  1 
ATOM   7392  C CG1 . ILE C 1 69  ? -40.117 18.988  62.161  1.00 50.57  ? 69  ILE C CG1 1 
ATOM   7393  C CG2 . ILE C 1 69  ? -41.272 18.015  64.185  1.00 54.14  ? 69  ILE C CG2 1 
ATOM   7394  C CD1 . ILE C 1 69  ? -38.708 19.182  62.645  1.00 52.54  ? 69  ILE C CD1 1 
ATOM   7395  N N   . PRO C 1 70  ? -43.990 20.144  64.562  1.00 51.63  ? 70  PRO C N   1 
ATOM   7396  C CA  . PRO C 1 70  ? -45.143 19.835  65.409  1.00 47.55  ? 70  PRO C CA  1 
ATOM   7397  C C   . PRO C 1 70  ? -46.423 19.893  64.571  1.00 50.58  ? 70  PRO C C   1 
ATOM   7398  O O   . PRO C 1 70  ? -47.341 19.116  64.847  1.00 47.77  ? 70  PRO C O   1 
ATOM   7399  C CB  . PRO C 1 70  ? -45.060 20.850  66.554  1.00 49.34  ? 70  PRO C CB  1 
ATOM   7400  C CG  . PRO C 1 70  ? -43.627 21.403  66.499  1.00 51.27  ? 70  PRO C CG  1 
ATOM   7401  C CD  . PRO C 1 70  ? -43.205 21.295  65.046  1.00 52.62  ? 70  PRO C CD  1 
ATOM   7402  N N   . GLU C 1 71  ? -46.448 20.746  63.518  1.00 49.55  ? 71  GLU C N   1 
ATOM   7403  C CA  . GLU C 1 71  ? -47.585 20.831  62.601  1.00 52.73  ? 71  GLU C CA  1 
ATOM   7404  C C   . GLU C 1 71  ? -47.689 19.549  61.774  1.00 55.74  ? 71  GLU C C   1 
ATOM   7405  O O   . GLU C 1 71  ? -48.777 19.006  61.598  1.00 55.11  ? 71  GLU C O   1 
ATOM   7406  C CB  . GLU C 1 71  ? -47.510 22.031  61.643  1.00 55.09  ? 71  GLU C CB  1 
ATOM   7407  C CG  . GLU C 1 71  ? -47.758 23.382  62.316  1.00 63.93  ? 71  GLU C CG  1 
ATOM   7408  C CD  . GLU C 1 71  ? -47.478 24.664  61.524  1.00 67.89  ? 71  GLU C CD  1 
ATOM   7409  O OE1 . GLU C 1 71  ? -47.211 24.612  60.293  1.00 59.01  ? 71  GLU C OE1 1 
ATOM   7410  O OE2 . GLU C 1 71  ? -47.536 25.742  62.156  1.00 72.72  ? 71  GLU C OE2 1 
ATOM   7411  N N   . VAL C 1 72  ? -46.559 19.062  61.250  1.00 54.36  ? 72  VAL C N   1 
ATOM   7412  C CA  . VAL C 1 72  ? -46.574 17.887  60.394  1.00 48.54  ? 72  VAL C CA  1 
ATOM   7413  C C   . VAL C 1 72  ? -47.051 16.671  61.192  1.00 45.86  ? 72  VAL C C   1 
ATOM   7414  O O   . VAL C 1 72  ? -47.888 15.908  60.730  1.00 47.37  ? 72  VAL C O   1 
ATOM   7415  C CB  . VAL C 1 72  ? -45.190 17.674  59.760  1.00 54.00  ? 72  VAL C CB  1 
ATOM   7416  C CG1 . VAL C 1 72  ? -45.035 16.286  59.160  1.00 53.48  ? 72  VAL C CG1 1 
ATOM   7417  C CG2 . VAL C 1 72  ? -44.883 18.750  58.721  1.00 53.34  ? 72  VAL C CG2 1 
ATOM   7418  N N   . LEU C 1 73  ? -46.551 16.496  62.409  1.00 44.85  ? 73  LEU C N   1 
ATOM   7419  C CA  . LEU C 1 73  ? -46.976 15.376  63.235  1.00 47.90  ? 73  LEU C CA  1 
ATOM   7420  C C   . LEU C 1 73  ? -48.443 15.518  63.616  1.00 55.97  ? 73  LEU C C   1 
ATOM   7421  O O   . LEU C 1 73  ? -49.158 14.524  63.683  1.00 59.65  ? 73  LEU C O   1 
ATOM   7422  C CB  . LEU C 1 73  ? -46.113 15.302  64.492  1.00 47.69  ? 73  LEU C CB  1 
ATOM   7423  C CG  . LEU C 1 73  ? -44.625 15.092  64.238  1.00 53.35  ? 73  LEU C CG  1 
ATOM   7424  C CD1 . LEU C 1 73  ? -43.908 14.848  65.560  1.00 58.62  ? 73  LEU C CD1 1 
ATOM   7425  C CD2 . LEU C 1 73  ? -44.382 13.951  63.240  1.00 49.06  ? 73  LEU C CD2 1 
ATOM   7426  N N   . GLU C 1 74  ? -48.860 16.765  63.866  1.00 68.95  ? 74  GLU C N   1 
ATOM   7427  C CA  . GLU C 1 74  ? -50.243 17.130  64.152  1.00 65.76  ? 74  GLU C CA  1 
ATOM   7428  C C   . GLU C 1 74  ? -51.173 16.678  63.016  1.00 58.23  ? 74  GLU C C   1 
ATOM   7429  O O   . GLU C 1 74  ? -52.135 15.955  63.282  1.00 55.70  ? 74  GLU C O   1 
ATOM   7430  C CB  . GLU C 1 74  ? -50.262 18.637  64.456  1.00 83.09  ? 74  GLU C CB  1 
ATOM   7431  C CG  . GLU C 1 74  ? -51.548 19.401  64.146  1.00 90.80  ? 74  GLU C CG  1 
ATOM   7432  C CD  . GLU C 1 74  ? -52.618 19.390  65.221  1.00 93.12  ? 74  GLU C CD  1 
ATOM   7433  O OE1 . GLU C 1 74  ? -52.725 18.383  65.971  1.00 88.04  ? 74  GLU C OE1 1 
ATOM   7434  O OE2 . GLU C 1 74  ? -53.325 20.411  65.316  1.00 98.77  ? 74  GLU C OE2 1 
ATOM   7435  N N   . LYS C 1 75  ? -50.878 17.054  61.758  1.00 49.07  ? 75  LYS C N   1 
ATOM   7436  C CA  . LYS C 1 75  ? -51.860 16.982  60.680  1.00 48.13  ? 75  LYS C CA  1 
ATOM   7437  C C   . LYS C 1 75  ? -51.793 15.699  59.846  1.00 48.65  ? 75  LYS C C   1 
ATOM   7438  O O   . LYS C 1 75  ? -52.762 15.374  59.162  1.00 47.11  ? 75  LYS C O   1 
ATOM   7439  C CB  . LYS C 1 75  ? -51.639 18.105  59.675  1.00 45.57  ? 75  LYS C CB  1 
ATOM   7440  C CG  . LYS C 1 75  ? -51.718 19.507  60.226  1.00 54.34  ? 75  LYS C CG  1 
ATOM   7441  C CD  . LYS C 1 75  ? -51.254 20.547  59.230  1.00 62.37  ? 75  LYS C CD  1 
ATOM   7442  C CE  . LYS C 1 75  ? -51.174 21.915  59.873  1.00 73.30  ? 75  LYS C CE  1 
ATOM   7443  N NZ  . LYS C 1 75  ? -52.483 22.276  60.469  1.00 74.92  ? 75  LYS C NZ  1 
ATOM   7444  N N   . LEU C 1 76  ? -50.634 15.026  59.804  1.00 49.94  ? 76  LEU C N   1 
ATOM   7445  C CA  . LEU C 1 76  ? -50.502 13.814  59.010  1.00 44.46  ? 76  LEU C CA  1 
ATOM   7446  C C   . LEU C 1 76  ? -51.366 12.702  59.608  1.00 44.96  ? 76  LEU C C   1 
ATOM   7447  O O   . LEU C 1 76  ? -51.403 12.526  60.830  1.00 46.55  ? 76  LEU C O   1 
ATOM   7448  C CB  . LEU C 1 76  ? -49.030 13.386  58.947  1.00 47.99  ? 76  LEU C CB  1 
ATOM   7449  C CG  . LEU C 1 76  ? -48.121 14.141  57.965  1.00 44.88  ? 76  LEU C CG  1 
ATOM   7450  C CD1 . LEU C 1 76  ? -46.703 13.634  58.091  1.00 45.00  ? 76  LEU C CD1 1 
ATOM   7451  C CD2 . LEU C 1 76  ? -48.563 13.989  56.520  1.00 43.90  ? 76  LEU C CD2 1 
ATOM   7452  N N   . PRO C 1 77  ? -52.089 11.919  58.761  1.00 41.12  ? 77  PRO C N   1 
ATOM   7453  C CA  . PRO C 1 77  ? -52.858 10.763  59.237  1.00 42.77  ? 77  PRO C CA  1 
ATOM   7454  C C   . PRO C 1 77  ? -52.041 9.753   60.050  1.00 47.09  ? 77  PRO C C   1 
ATOM   7455  O O   . PRO C 1 77  ? -50.986 9.300   59.592  1.00 41.52  ? 77  PRO C O   1 
ATOM   7456  C CB  . PRO C 1 77  ? -53.323 10.061  57.945  1.00 41.67  ? 77  PRO C CB  1 
ATOM   7457  C CG  . PRO C 1 77  ? -53.282 11.147  56.880  1.00 41.17  ? 77  PRO C CG  1 
ATOM   7458  C CD  . PRO C 1 77  ? -52.191 12.107  57.302  1.00 39.89  ? 77  PRO C CD  1 
ATOM   7459  N N   . LYS C 1 78  ? -52.571 9.372   61.223  1.00 47.49  ? 78  LYS C N   1 
ATOM   7460  C CA  . LYS C 1 78  ? -51.921 8.434   62.122  1.00 49.19  ? 78  LYS C CA  1 
ATOM   7461  C C   . LYS C 1 78  ? -52.229 6.981   61.730  1.00 50.36  ? 78  LYS C C   1 
ATOM   7462  O O   . LYS C 1 78  ? -53.231 6.686   61.074  1.00 44.15  ? 78  LYS C O   1 
ATOM   7463  C CB  . LYS C 1 78  ? -52.399 8.664   63.556  1.00 53.86  ? 78  LYS C CB  1 
ATOM   7464  C CG  . LYS C 1 78  ? -52.328 10.104  64.037  1.00 60.00  ? 78  LYS C CG  1 
ATOM   7465  C CD  . LYS C 1 78  ? -50.958 10.565  64.474  1.00 64.37  ? 78  LYS C CD  1 
ATOM   7466  C CE  . LYS C 1 78  ? -50.923 12.060  64.693  1.00 60.08  ? 78  LYS C CE  1 
ATOM   7467  N NZ  . LYS C 1 78  ? -51.213 12.781  63.430  1.00 58.33  ? 78  LYS C NZ  1 
ATOM   7468  N N   . VAL C 1 79  ? -51.356 6.060   62.174  1.00 51.07  ? 79  VAL C N   1 
ATOM   7469  C CA  . VAL C 1 79  ? -51.581 4.641   61.971  1.00 59.96  ? 79  VAL C CA  1 
ATOM   7470  C C   . VAL C 1 79  ? -52.564 4.165   63.041  1.00 57.86  ? 79  VAL C C   1 
ATOM   7471  O O   . VAL C 1 79  ? -52.408 4.477   64.220  1.00 57.94  ? 79  VAL C O   1 
ATOM   7472  C CB  . VAL C 1 79  ? -50.258 3.840   61.958  1.00 63.82  ? 79  VAL C CB  1 
ATOM   7473  C CG1 . VAL C 1 79  ? -50.481 2.345   61.734  1.00 59.57  ? 79  VAL C CG1 1 
ATOM   7474  C CG2 . VAL C 1 79  ? -49.281 4.383   60.922  1.00 61.26  ? 79  VAL C CG2 1 
ATOM   7475  N N   . PRO C 1 80  ? -53.642 3.430   62.671  1.00 59.52  ? 80  PRO C N   1 
ATOM   7476  C CA  . PRO C 1 80  ? -54.544 2.862   63.683  1.00 59.43  ? 80  PRO C CA  1 
ATOM   7477  C C   . PRO C 1 80  ? -53.789 1.905   64.618  1.00 59.44  ? 80  PRO C C   1 
ATOM   7478  O O   . PRO C 1 80  ? -53.066 1.011   64.169  1.00 59.03  ? 80  PRO C O   1 
ATOM   7479  C CB  . PRO C 1 80  ? -55.634 2.138   62.864  1.00 58.60  ? 80  PRO C CB  1 
ATOM   7480  C CG  . PRO C 1 80  ? -55.476 2.649   61.419  1.00 55.28  ? 80  PRO C CG  1 
ATOM   7481  C CD  . PRO C 1 80  ? -54.041 3.114   61.283  1.00 53.89  ? 80  PRO C CD  1 
ATOM   7482  N N   . GLY C 1 81  ? -53.946 2.123   65.929  1.00 61.57  ? 81  GLY C N   1 
ATOM   7483  C CA  . GLY C 1 81  ? -53.273 1.339   66.955  1.00 59.94  ? 81  GLY C CA  1 
ATOM   7484  C C   . GLY C 1 81  ? -51.987 2.003   67.456  1.00 66.96  ? 81  GLY C C   1 
ATOM   7485  O O   . GLY C 1 81  ? -51.409 1.531   68.430  1.00 65.12  ? 81  GLY C O   1 
ATOM   7486  N N   . ALA C 1 82  ? -51.578 3.111   66.808  1.00 63.12  ? 82  ALA C N   1 
ATOM   7487  C CA  . ALA C 1 82  ? -50.247 3.679   66.952  1.00 55.95  ? 82  ALA C CA  1 
ATOM   7488  C C   . ALA C 1 82  ? -50.283 5.206   67.018  1.00 57.81  ? 82  ALA C C   1 
ATOM   7489  O O   . ALA C 1 82  ? -51.155 5.847   66.439  1.00 55.53  ? 82  ALA C O   1 
ATOM   7490  C CB  . ALA C 1 82  ? -49.394 3.221   65.798  1.00 57.51  ? 82  ALA C CB  1 
ATOM   7491  N N   . GLU C 1 83  ? -49.242 5.776   67.643  1.00 59.10  ? 83  GLU C N   1 
ATOM   7492  C CA  . GLU C 1 83  ? -49.154 7.187   67.991  1.00 62.76  ? 83  GLU C CA  1 
ATOM   7493  C C   . GLU C 1 83  ? -48.702 8.037   66.797  1.00 61.76  ? 83  GLU C C   1 
ATOM   7494  O O   . GLU C 1 83  ? -48.951 9.241   66.744  1.00 58.76  ? 83  GLU C O   1 
ATOM   7495  C CB  . GLU C 1 83  ? -48.222 7.298   69.201  1.00 66.15  ? 83  GLU C CB  1 
ATOM   7496  C CG  . GLU C 1 83  ? -47.880 8.712   69.636  1.00 82.06  ? 83  GLU C CG  1 
ATOM   7497  C CD  . GLU C 1 83  ? -46.930 8.770   70.821  1.00 95.82  ? 83  GLU C CD  1 
ATOM   7498  O OE1 . GLU C 1 83  ? -46.234 9.799   70.981  1.00 96.73  ? 83  GLU C OE1 1 
ATOM   7499  O OE2 . GLU C 1 83  ? -46.882 7.779   71.580  1.00 111.50 ? 83  GLU C OE2 1 
ATOM   7500  N N   . MET C 1 84  ? -48.058 7.412   65.812  1.00 62.88  ? 84  MET C N   1 
ATOM   7501  C CA  . MET C 1 84  ? -47.297 8.168   64.834  1.00 55.37  ? 84  MET C CA  1 
ATOM   7502  C C   . MET C 1 84  ? -47.895 8.012   63.449  1.00 51.89  ? 84  MET C C   1 
ATOM   7503  O O   . MET C 1 84  ? -48.603 7.041   63.181  1.00 51.92  ? 84  MET C O   1 
ATOM   7504  C CB  . MET C 1 84  ? -45.842 7.700   64.802  1.00 61.45  ? 84  MET C CB  1 
ATOM   7505  C CG  . MET C 1 84  ? -45.080 8.152   66.022  1.00 67.73  ? 84  MET C CG  1 
ATOM   7506  S SD  . MET C 1 84  ? -44.959 9.951   66.090  1.00 61.72  ? 84  MET C SD  1 
ATOM   7507  C CE  . MET C 1 84  ? -44.040 10.152  67.623  1.00 72.85  ? 84  MET C CE  1 
ATOM   7508  N N   . PRO C 1 85  ? -47.622 8.992   62.552  1.00 49.29  ? 85  PRO C N   1 
ATOM   7509  C CA  . PRO C 1 85  ? -48.141 8.983   61.185  1.00 46.74  ? 85  PRO C CA  1 
ATOM   7510  C C   . PRO C 1 85  ? -47.564 7.924   60.254  1.00 43.63  ? 85  PRO C C   1 
ATOM   7511  O O   . PRO C 1 85  ? -46.445 7.476   60.446  1.00 44.54  ? 85  PRO C O   1 
ATOM   7512  C CB  . PRO C 1 85  ? -47.742 10.356  60.600  1.00 51.44  ? 85  PRO C CB  1 
ATOM   7513  C CG  . PRO C 1 85  ? -47.336 11.198  61.790  1.00 48.39  ? 85  PRO C CG  1 
ATOM   7514  C CD  . PRO C 1 85  ? -46.859 10.220  62.842  1.00 46.67  ? 85  PRO C CD  1 
ATOM   7515  N N   . TYR C 1 86  ? -48.324 7.585   59.209  1.00 42.44  ? 86  TYR C N   1 
ATOM   7516  C CA  . TYR C 1 86  ? -47.801 6.868   58.060  1.00 42.92  ? 86  TYR C CA  1 
ATOM   7517  C C   . TYR C 1 86  ? -46.674 7.674   57.423  1.00 40.84  ? 86  TYR C C   1 
ATOM   7518  O O   . TYR C 1 86  ? -46.890 8.815   57.024  1.00 37.96  ? 86  TYR C O   1 
ATOM   7519  C CB  . TYR C 1 86  ? -48.839 6.680   56.949  1.00 45.47  ? 86  TYR C CB  1 
ATOM   7520  C CG  . TYR C 1 86  ? -49.983 5.747   57.253  1.00 53.17  ? 86  TYR C CG  1 
ATOM   7521  C CD1 . TYR C 1 86  ? -51.035 6.128   58.075  1.00 55.77  ? 86  TYR C CD1 1 
ATOM   7522  C CD2 . TYR C 1 86  ? -50.037 4.490   56.677  1.00 58.11  ? 86  TYR C CD2 1 
ATOM   7523  C CE1 . TYR C 1 86  ? -52.093 5.273   58.338  1.00 62.97  ? 86  TYR C CE1 1 
ATOM   7524  C CE2 . TYR C 1 86  ? -51.091 3.627   56.931  1.00 67.15  ? 86  TYR C CE2 1 
ATOM   7525  C CZ  . TYR C 1 86  ? -52.110 4.009   57.785  1.00 66.04  ? 86  TYR C CZ  1 
ATOM   7526  O OH  . TYR C 1 86  ? -53.161 3.172   58.055  1.00 70.56  ? 86  TYR C OH  1 
ATOM   7527  N N   . VAL C 1 87  ? -45.501 7.038   57.271  1.00 41.33  ? 87  VAL C N   1 
ATOM   7528  C CA  . VAL C 1 87  ? -44.362 7.653   56.608  1.00 37.86  ? 87  VAL C CA  1 
ATOM   7529  C C   . VAL C 1 87  ? -44.739 7.965   55.164  1.00 36.66  ? 87  VAL C C   1 
ATOM   7530  O O   . VAL C 1 87  ? -44.216 8.906   54.576  1.00 41.42  ? 87  VAL C O   1 
ATOM   7531  C CB  . VAL C 1 87  ? -43.104 6.753   56.680  1.00 35.51  ? 87  VAL C CB  1 
ATOM   7532  C CG1 . VAL C 1 87  ? -41.936 7.322   55.877  1.00 32.34  ? 87  VAL C CG1 1 
ATOM   7533  C CG2 . VAL C 1 87  ? -42.673 6.502   58.118  1.00 31.18  ? 87  VAL C CG2 1 
ATOM   7534  N N   . GLU C 1 88  ? -45.631 7.140   54.606  1.00 37.04  ? 88  GLU C N   1 
ATOM   7535  C CA  . GLU C 1 88  ? -46.165 7.270   53.257  1.00 37.24  ? 88  GLU C CA  1 
ATOM   7536  C C   . GLU C 1 88  ? -46.872 8.620   53.082  1.00 39.05  ? 88  GLU C C   1 
ATOM   7537  O O   . GLU C 1 88  ? -46.853 9.194   51.986  1.00 41.59  ? 88  GLU C O   1 
ATOM   7538  C CB  . GLU C 1 88  ? -47.127 6.107   52.993  1.00 40.03  ? 88  GLU C CB  1 
ATOM   7539  C CG  . GLU C 1 88  ? -46.463 4.737   53.068  1.00 43.92  ? 88  GLU C CG  1 
ATOM   7540  C CD  . GLU C 1 88  ? -46.542 3.941   54.367  1.00 46.01  ? 88  GLU C CD  1 
ATOM   7541  O OE1 . GLU C 1 88  ? -46.253 4.496   55.501  1.00 51.74  ? 88  GLU C OE1 1 
ATOM   7542  O OE2 . GLU C 1 88  ? -46.841 2.723   54.247  1.00 48.26  ? 88  GLU C OE2 1 
ATOM   7543  N N   . GLY C 1 89  ? -47.513 9.110   54.161  1.00 34.22  ? 89  GLY C N   1 
ATOM   7544  C CA  . GLY C 1 89  ? -48.209 10.379  54.132  1.00 31.65  ? 89  GLY C CA  1 
ATOM   7545  C C   . GLY C 1 89  ? -47.216 11.524  54.044  1.00 33.68  ? 89  GLY C C   1 
ATOM   7546  O O   . GLY C 1 89  ? -47.443 12.503  53.327  1.00 30.47  ? 89  GLY C O   1 
ATOM   7547  N N   . HIS C 1 90  ? -46.114 11.386  54.792  1.00 28.53  ? 90  HIS C N   1 
ATOM   7548  C CA  . HIS C 1 90  ? -45.102 12.413  54.770  1.00 31.61  ? 90  HIS C CA  1 
ATOM   7549  C C   . HIS C 1 90  ? -44.493 12.491  53.383  1.00 33.87  ? 90  HIS C C   1 
ATOM   7550  O O   . HIS C 1 90  ? -44.136 13.574  52.935  1.00 36.31  ? 90  HIS C O   1 
ATOM   7551  C CB  . HIS C 1 90  ? -44.030 12.184  55.827  1.00 32.70  ? 90  HIS C CB  1 
ATOM   7552  C CG  . HIS C 1 90  ? -43.086 13.337  55.900  1.00 37.78  ? 90  HIS C CG  1 
ATOM   7553  N ND1 . HIS C 1 90  ? -43.486 14.635  56.100  1.00 39.89  ? 90  HIS C ND1 1 
ATOM   7554  C CD2 . HIS C 1 90  ? -41.738 13.362  55.738  1.00 42.92  ? 90  HIS C CD2 1 
ATOM   7555  C CE1 . HIS C 1 90  ? -42.421 15.430  56.118  1.00 42.94  ? 90  HIS C CE1 1 
ATOM   7556  N NE2 . HIS C 1 90  ? -41.325 14.658  55.904  1.00 46.52  ? 90  HIS C NE2 1 
ATOM   7557  N N   . PHE C 1 91  ? -44.391 11.342  52.699  1.00 37.82  ? 91  PHE C N   1 
ATOM   7558  C CA  . PHE C 1 91  ? -43.853 11.315  51.348  1.00 37.23  ? 91  PHE C CA  1 
ATOM   7559  C C   . PHE C 1 91  ? -44.786 12.064  50.382  1.00 39.43  ? 91  PHE C C   1 
ATOM   7560  O O   . PHE C 1 91  ? -44.341 12.786  49.484  1.00 40.24  ? 91  PHE C O   1 
ATOM   7561  C CB  . PHE C 1 91  ? -43.607 9.862   50.936  1.00 34.93  ? 91  PHE C CB  1 
ATOM   7562  C CG  . PHE C 1 91  ? -42.780 9.713   49.679  1.00 38.45  ? 91  PHE C CG  1 
ATOM   7563  C CD1 . PHE C 1 91  ? -41.576 10.402  49.521  1.00 40.08  ? 91  PHE C CD1 1 
ATOM   7564  C CD2 . PHE C 1 91  ? -43.187 8.880   48.649  1.00 36.51  ? 91  PHE C CD2 1 
ATOM   7565  C CE1 . PHE C 1 91  ? -40.803 10.255  48.372  1.00 39.69  ? 91  PHE C CE1 1 
ATOM   7566  C CE2 . PHE C 1 91  ? -42.413 8.740   47.500  1.00 35.81  ? 91  PHE C CE2 1 
ATOM   7567  C CZ  . PHE C 1 91  ? -41.222 9.410   47.366  1.00 37.12  ? 91  PHE C CZ  1 
ATOM   7568  N N   . TYR C 1 92  ? -46.092 11.832  50.543  1.00 40.63  ? 92  TYR C N   1 
ATOM   7569  C CA  . TYR C 1 92  ? -47.131 12.523  49.787  1.00 43.89  ? 92  TYR C CA  1 
ATOM   7570  C C   . TYR C 1 92  ? -46.967 14.029  49.970  1.00 37.02  ? 92  TYR C C   1 
ATOM   7571  O O   . TYR C 1 92  ? -46.953 14.789  49.020  1.00 39.54  ? 92  TYR C O   1 
ATOM   7572  C CB  . TYR C 1 92  ? -48.516 12.034  50.245  1.00 49.71  ? 92  TYR C CB  1 
ATOM   7573  C CG  . TYR C 1 92  ? -49.675 12.561  49.438  1.00 48.43  ? 92  TYR C CG  1 
ATOM   7574  C CD1 . TYR C 1 92  ? -50.122 13.859  49.605  1.00 47.98  ? 92  TYR C CD1 1 
ATOM   7575  C CD2 . TYR C 1 92  ? -50.305 11.772  48.483  1.00 50.43  ? 92  TYR C CD2 1 
ATOM   7576  C CE1 . TYR C 1 92  ? -51.163 14.368  48.844  1.00 49.73  ? 92  TYR C CE1 1 
ATOM   7577  C CE2 . TYR C 1 92  ? -51.355 12.263  47.720  1.00 52.74  ? 92  TYR C CE2 1 
ATOM   7578  C CZ  . TYR C 1 92  ? -51.778 13.572  47.897  1.00 50.50  ? 92  TYR C CZ  1 
ATOM   7579  O OH  . TYR C 1 92  ? -52.801 14.118  47.175  1.00 55.36  ? 92  TYR C OH  1 
ATOM   7580  N N   . LEU C 1 93  ? -46.785 14.447  51.216  1.00 36.10  ? 93  LEU C N   1 
ATOM   7581  C CA  . LEU C 1 93  ? -46.695 15.850  51.559  1.00 34.94  ? 93  LEU C CA  1 
ATOM   7582  C C   . LEU C 1 93  ? -45.501 16.506  50.888  1.00 34.10  ? 93  LEU C C   1 
ATOM   7583  O O   . LEU C 1 93  ? -45.602 17.628  50.400  1.00 41.54  ? 93  LEU C O   1 
ATOM   7584  C CB  . LEU C 1 93  ? -46.578 15.962  53.075  1.00 32.78  ? 93  LEU C CB  1 
ATOM   7585  C CG  . LEU C 1 93  ? -46.236 17.361  53.575  1.00 36.18  ? 93  LEU C CG  1 
ATOM   7586  C CD1 . LEU C 1 93  ? -47.265 18.383  53.041  1.00 37.51  ? 93  LEU C CD1 1 
ATOM   7587  C CD2 . LEU C 1 93  ? -46.195 17.376  55.097  1.00 34.35  ? 93  LEU C CD2 1 
ATOM   7588  N N   . LEU C 1 94  ? -44.362 15.818  50.916  1.00 36.56  ? 94  LEU C N   1 
ATOM   7589  C CA  . LEU C 1 94  ? -43.136 16.345  50.340  1.00 36.86  ? 94  LEU C CA  1 
ATOM   7590  C C   . LEU C 1 94  ? -43.257 16.434  48.821  1.00 32.55  ? 94  LEU C C   1 
ATOM   7591  O O   . LEU C 1 94  ? -42.749 17.372  48.240  1.00 33.00  ? 94  LEU C O   1 
ATOM   7592  C CB  . LEU C 1 94  ? -41.965 15.446  50.750  1.00 35.99  ? 94  LEU C CB  1 
ATOM   7593  C CG  . LEU C 1 94  ? -41.618 15.486  52.234  1.00 36.64  ? 94  LEU C CG  1 
ATOM   7594  C CD1 . LEU C 1 94  ? -40.360 14.669  52.497  1.00 37.94  ? 94  LEU C CD1 1 
ATOM   7595  C CD2 . LEU C 1 94  ? -41.469 16.920  52.742  1.00 35.32  ? 94  LEU C CD2 1 
ATOM   7596  N N   . LEU C 1 95  ? -43.912 15.463  48.186  1.00 31.62  ? 95  LEU C N   1 
ATOM   7597  C CA  . LEU C 1 95  ? -44.056 15.480  46.744  1.00 39.25  ? 95  LEU C CA  1 
ATOM   7598  C C   . LEU C 1 95  ? -45.003 16.597  46.300  1.00 44.53  ? 95  LEU C C   1 
ATOM   7599  O O   . LEU C 1 95  ? -44.699 17.291  45.323  1.00 32.90  ? 95  LEU C O   1 
ATOM   7600  C CB  . LEU C 1 95  ? -44.567 14.127  46.248  1.00 40.33  ? 95  LEU C CB  1 
ATOM   7601  C CG  . LEU C 1 95  ? -43.485 13.088  45.991  1.00 43.15  ? 95  LEU C CG  1 
ATOM   7602  C CD1 . LEU C 1 95  ? -44.093 11.751  45.661  1.00 49.65  ? 95  LEU C CD1 1 
ATOM   7603  C CD2 . LEU C 1 95  ? -42.555 13.520  44.871  1.00 43.51  ? 95  LEU C CD2 1 
ATOM   7604  N N   . THR C 1 96  ? -46.147 16.734  46.997  1.00 43.12  ? 96  THR C N   1 
ATOM   7605  C CA  . THR C 1 96  ? -47.269 17.490  46.463  1.00 43.82  ? 96  THR C CA  1 
ATOM   7606  C C   . THR C 1 96  ? -47.322 18.876  47.075  1.00 46.73  ? 96  THR C C   1 
ATOM   7607  O O   . THR C 1 96  ? -47.729 19.811  46.401  1.00 50.13  ? 96  THR C O   1 
ATOM   7608  C CB  . THR C 1 96  ? -48.633 16.831  46.696  1.00 40.00  ? 96  THR C CB  1 
ATOM   7609  O OG1 . THR C 1 96  ? -48.909 16.837  48.103  1.00 38.12  ? 96  THR C OG1 1 
ATOM   7610  C CG2 . THR C 1 96  ? -48.705 15.432  46.115  1.00 39.26  ? 96  THR C CG2 1 
ATOM   7611  N N   . GLY C 1 97  ? -46.955 18.974  48.355  1.00 45.73  ? 97  GLY C N   1 
ATOM   7612  C CA  . GLY C 1 97  ? -47.181 20.188  49.122  1.00 41.12  ? 97  GLY C CA  1 
ATOM   7613  C C   . GLY C 1 97  ? -48.456 20.122  49.967  1.00 45.65  ? 97  GLY C C   1 
ATOM   7614  O O   . GLY C 1 97  ? -48.705 21.018  50.777  1.00 44.99  ? 97  GLY C O   1 
ATOM   7615  N N   . ASP C 1 98  ? -49.238 19.040  49.814  1.00 50.68  ? 98  ASP C N   1 
ATOM   7616  C CA  . ASP C 1 98  ? -50.549 18.920  50.443  1.00 49.06  ? 98  ASP C CA  1 
ATOM   7617  C C   . ASP C 1 98  ? -50.518 17.889  51.560  1.00 42.56  ? 98  ASP C C   1 
ATOM   7618  O O   . ASP C 1 98  ? -49.922 16.832  51.390  1.00 33.35  ? 98  ASP C O   1 
ATOM   7619  C CB  . ASP C 1 98  ? -51.603 18.399  49.462  1.00 54.69  ? 98  ASP C CB  1 
ATOM   7620  C CG  . ASP C 1 98  ? -51.898 19.287  48.269  1.00 60.77  ? 98  ASP C CG  1 
ATOM   7621  O OD1 . ASP C 1 98  ? -51.575 20.506  48.342  1.00 56.54  ? 98  ASP C OD1 1 
ATOM   7622  O OD2 . ASP C 1 98  ? -52.447 18.740  47.264  1.00 71.55  ? 98  ASP C OD2 1 
ATOM   7623  N N   . VAL C 1 99  ? -51.219 18.173  52.668  1.00 40.96  ? 99  VAL C N   1 
ATOM   7624  C CA  . VAL C 1 99  ? -51.497 17.137  53.651  1.00 39.45  ? 99  VAL C CA  1 
ATOM   7625  C C   . VAL C 1 99  ? -52.506 16.182  53.025  1.00 40.61  ? 99  VAL C C   1 
ATOM   7626  O O   . VAL C 1 99  ? -53.581 16.613  52.628  1.00 44.29  ? 99  VAL C O   1 
ATOM   7627  C CB  . VAL C 1 99  ? -52.037 17.688  54.988  1.00 38.10  ? 99  VAL C CB  1 
ATOM   7628  C CG1 . VAL C 1 99  ? -52.374 16.567  55.970  1.00 34.52  ? 99  VAL C CG1 1 
ATOM   7629  C CG2 . VAL C 1 99  ? -51.063 18.673  55.606  1.00 42.31  ? 99  VAL C CG2 1 
ATOM   7630  N N   . PRO C 1 100 ? -52.207 14.868  52.901  1.00 43.44  ? 100 PRO C N   1 
ATOM   7631  C CA  . PRO C 1 100 ? -53.181 13.918  52.360  1.00 40.48  ? 100 PRO C CA  1 
ATOM   7632  C C   . PRO C 1 100 ? -54.285 13.507  53.351  1.00 42.61  ? 100 PRO C C   1 
ATOM   7633  O O   . PRO C 1 100 ? -54.132 13.533  54.593  1.00 38.99  ? 100 PRO C O   1 
ATOM   7634  C CB  . PRO C 1 100 ? -52.304 12.716  51.982  1.00 37.53  ? 100 PRO C CB  1 
ATOM   7635  C CG  . PRO C 1 100 ? -51.204 12.757  53.008  1.00 41.11  ? 100 PRO C CG  1 
ATOM   7636  C CD  . PRO C 1 100 ? -50.927 14.231  53.248  1.00 42.17  ? 100 PRO C CD  1 
ATOM   7637  N N   . THR C 1 101 ? -55.423 13.131  52.755  1.00 42.15  ? 101 THR C N   1 
ATOM   7638  C CA  . THR C 1 101 ? -56.541 12.538  53.470  1.00 46.80  ? 101 THR C CA  1 
ATOM   7639  C C   . THR C 1 101 ? -56.142 11.119  53.857  1.00 53.41  ? 101 THR C C   1 
ATOM   7640  O O   . THR C 1 101 ? -55.236 10.536  53.260  1.00 60.84  ? 101 THR C O   1 
ATOM   7641  C CB  . THR C 1 101 ? -57.830 12.593  52.624  1.00 46.04  ? 101 THR C CB  1 
ATOM   7642  O OG1 . THR C 1 101 ? -57.775 11.623  51.576  1.00 43.67  ? 101 THR C OG1 1 
ATOM   7643  C CG2 . THR C 1 101 ? -58.087 13.967  52.020  1.00 41.64  ? 101 THR C CG2 1 
ATOM   7644  N N   . GLU C 1 102 ? -56.856 10.557  54.832  1.00 63.42  ? 102 GLU C N   1 
ATOM   7645  C CA  . GLU C 1 102 ? -56.659 9.172   55.230  1.00 61.23  ? 102 GLU C CA  1 
ATOM   7646  C C   . GLU C 1 102 ? -56.790 8.245   54.017  1.00 56.39  ? 102 GLU C C   1 
ATOM   7647  O O   . GLU C 1 102 ? -56.211 7.177   54.001  1.00 57.05  ? 102 GLU C O   1 
ATOM   7648  C CB  . GLU C 1 102 ? -57.670 8.835   56.324  1.00 69.64  ? 102 GLU C CB  1 
ATOM   7649  C CG  . GLU C 1 102 ? -57.323 7.615   57.147  1.00 78.72  ? 102 GLU C CG  1 
ATOM   7650  C CD  . GLU C 1 102 ? -58.148 7.533   58.422  1.00 91.49  ? 102 GLU C CD  1 
ATOM   7651  O OE1 . GLU C 1 102 ? -58.006 8.456   59.267  1.00 90.67  ? 102 GLU C OE1 1 
ATOM   7652  O OE2 . GLU C 1 102 ? -58.953 6.564   58.562  1.00 89.49  ? 102 GLU C OE2 1 
ATOM   7653  N N   . LYS C 1 103 ? -57.511 8.666   52.976  1.00 64.92  ? 103 LYS C N   1 
ATOM   7654  C CA  . LYS C 1 103 ? -57.785 7.808   51.836  1.00 66.32  ? 103 LYS C CA  1 
ATOM   7655  C C   . LYS C 1 103 ? -56.617 7.844   50.849  1.00 62.94  ? 103 LYS C C   1 
ATOM   7656  O O   . LYS C 1 103 ? -56.272 6.795   50.295  1.00 59.77  ? 103 LYS C O   1 
ATOM   7657  C CB  . LYS C 1 103 ? -59.134 8.230   51.240  1.00 82.52  ? 103 LYS C CB  1 
ATOM   7658  C CG  . LYS C 1 103 ? -59.931 7.146   50.517  1.00 92.01  ? 103 LYS C CG  1 
ATOM   7659  C CD  . LYS C 1 103 ? -59.697 7.140   49.020  1.00 103.33 ? 103 LYS C CD  1 
ATOM   7660  C CE  . LYS C 1 103 ? -60.321 8.324   48.307  1.00 105.84 ? 103 LYS C CE  1 
ATOM   7661  N NZ  . LYS C 1 103 ? -59.465 8.790   47.192  1.00 106.23 ? 103 LYS C NZ  1 
ATOM   7662  N N   . GLU C 1 104 ? -55.997 9.022   50.649  1.00 57.56  ? 104 GLU C N   1 
ATOM   7663  C CA  . GLU C 1 104 ? -54.865 9.189   49.736  1.00 57.73  ? 104 GLU C CA  1 
ATOM   7664  C C   . GLU C 1 104 ? -53.585 8.519   50.259  1.00 55.08  ? 104 GLU C C   1 
ATOM   7665  O O   . GLU C 1 104 ? -52.745 8.094   49.466  1.00 48.12  ? 104 GLU C O   1 
ATOM   7666  C CB  . GLU C 1 104 ? -54.531 10.666  49.540  1.00 58.58  ? 104 GLU C CB  1 
ATOM   7667  C CG  . GLU C 1 104 ? -55.679 11.456  48.943  1.00 67.51  ? 104 GLU C CG  1 
ATOM   7668  C CD  . GLU C 1 104 ? -55.515 12.970  49.011  1.00 71.62  ? 104 GLU C CD  1 
ATOM   7669  O OE1 . GLU C 1 104 ? -55.299 13.509  50.106  1.00 61.33  ? 104 GLU C OE1 1 
ATOM   7670  O OE2 . GLU C 1 104 ? -55.644 13.619  47.967  1.00 96.56  ? 104 GLU C OE2 1 
ATOM   7671  N N   . VAL C 1 105 ? -53.419 8.477   51.588  1.00 50.50  ? 105 VAL C N   1 
ATOM   7672  C CA  . VAL C 1 105 ? -52.309 7.784   52.216  1.00 57.70  ? 105 VAL C CA  1 
ATOM   7673  C C   . VAL C 1 105 ? -52.415 6.283   51.961  1.00 60.98  ? 105 VAL C C   1 
ATOM   7674  O O   . VAL C 1 105 ? -51.391 5.625   51.823  1.00 62.79  ? 105 VAL C O   1 
ATOM   7675  C CB  . VAL C 1 105 ? -52.258 8.063   53.730  1.00 61.67  ? 105 VAL C CB  1 
ATOM   7676  C CG1 . VAL C 1 105 ? -51.305 7.138   54.474  1.00 64.76  ? 105 VAL C CG1 1 
ATOM   7677  C CG2 . VAL C 1 105 ? -51.919 9.513   54.007  1.00 66.75  ? 105 VAL C CG2 1 
ATOM   7678  N N   . LYS C 1 106 ? -53.638 5.744   51.924  1.00 60.80  ? 106 LYS C N   1 
ATOM   7679  C CA  . LYS C 1 106 ? -53.828 4.312   51.796  1.00 62.45  ? 106 LYS C CA  1 
ATOM   7680  C C   . LYS C 1 106 ? -53.556 3.870   50.365  1.00 59.20  ? 106 LYS C C   1 
ATOM   7681  O O   . LYS C 1 106 ? -53.190 2.726   50.127  1.00 61.27  ? 106 LYS C O   1 
ATOM   7682  C CB  . LYS C 1 106 ? -55.204 3.887   52.318  1.00 64.67  ? 106 LYS C CB  1 
ATOM   7683  C CG  . LYS C 1 106 ? -55.388 4.139   53.817  1.00 83.82  ? 106 LYS C CG  1 
ATOM   7684  C CD  . LYS C 1 106 ? -55.849 2.926   54.650  1.00 96.70  ? 106 LYS C CD  1 
ATOM   7685  C CE  . LYS C 1 106 ? -54.690 1.970   54.932  1.00 98.34  ? 106 LYS C CE  1 
ATOM   7686  N NZ  . LYS C 1 106 ? -55.164 0.614   55.324  1.00 92.33  ? 106 LYS C NZ  1 
ATOM   7687  N N   . GLU C 1 107 ? -53.677 4.781   49.406  1.00 65.47  ? 107 GLU C N   1 
ATOM   7688  C CA  . GLU C 1 107 ? -53.378 4.420   48.030  1.00 68.27  ? 107 GLU C CA  1 
ATOM   7689  C C   . GLU C 1 107 ? -51.862 4.317   47.865  1.00 57.33  ? 107 GLU C C   1 
ATOM   7690  O O   . GLU C 1 107 ? -51.377 3.407   47.201  1.00 46.82  ? 107 GLU C O   1 
ATOM   7691  C CB  . GLU C 1 107 ? -54.055 5.399   47.076  1.00 72.81  ? 107 GLU C CB  1 
ATOM   7692  C CG  . GLU C 1 107 ? -55.569 5.386   47.236  1.00 89.68  ? 107 GLU C CG  1 
ATOM   7693  C CD  . GLU C 1 107 ? -56.362 6.325   46.343  1.00 101.69 ? 107 GLU C CD  1 
ATOM   7694  O OE1 . GLU C 1 107 ? -56.087 7.563   46.359  1.00 118.15 ? 107 GLU C OE1 1 
ATOM   7695  O OE2 . GLU C 1 107 ? -57.269 5.814   45.660  1.00 95.31  ? 107 GLU C OE2 1 
ATOM   7696  N N   . VAL C 1 108 ? -51.128 5.235   48.500  1.00 48.35  ? 108 VAL C N   1 
ATOM   7697  C CA  . VAL C 1 108 ? -49.675 5.230   48.450  1.00 51.06  ? 108 VAL C CA  1 
ATOM   7698  C C   . VAL C 1 108 ? -49.131 3.982   49.147  1.00 52.38  ? 108 VAL C C   1 
ATOM   7699  O O   . VAL C 1 108 ? -48.263 3.309   48.597  1.00 46.94  ? 108 VAL C O   1 
ATOM   7700  C CB  . VAL C 1 108 ? -49.079 6.500   49.081  1.00 52.31  ? 108 VAL C CB  1 
ATOM   7701  C CG1 . VAL C 1 108 ? -47.558 6.410   49.213  1.00 45.95  ? 108 VAL C CG1 1 
ATOM   7702  C CG2 . VAL C 1 108 ? -49.490 7.745   48.303  1.00 54.59  ? 108 VAL C CG2 1 
ATOM   7703  N N   . ALA C 1 109 ? -49.640 3.702   50.356  1.00 48.67  ? 109 ALA C N   1 
ATOM   7704  C CA  . ALA C 1 109 ? -49.263 2.533   51.143  1.00 44.57  ? 109 ALA C CA  1 
ATOM   7705  C C   . ALA C 1 109 ? -49.451 1.249   50.350  1.00 46.75  ? 109 ALA C C   1 
ATOM   7706  O O   . ALA C 1 109 ? -48.591 0.368   50.443  1.00 50.45  ? 109 ALA C O   1 
ATOM   7707  C CB  . ALA C 1 109 ? -50.044 2.474   52.437  1.00 47.02  ? 109 ALA C CB  1 
ATOM   7708  N N   . GLU C 1 110 ? -50.565 1.155   49.599  1.00 47.04  ? 110 GLU C N   1 
ATOM   7709  C CA  . GLU C 1 110 ? -50.822 0.021   48.723  1.00 49.93  ? 110 GLU C CA  1 
ATOM   7710  C C   . GLU C 1 110 ? -49.824 0.025   47.576  1.00 42.77  ? 110 GLU C C   1 
ATOM   7711  O O   . GLU C 1 110 ? -49.455 -1.035  47.109  1.00 44.72  ? 110 GLU C O   1 
ATOM   7712  C CB  . GLU C 1 110 ? -52.237 0.001   48.109  1.00 61.77  ? 110 GLU C CB  1 
ATOM   7713  C CG  . GLU C 1 110 ? -53.357 -0.374  49.083  1.00 73.86  ? 110 GLU C CG  1 
ATOM   7714  C CD  . GLU C 1 110 ? -53.199 -1.678  49.863  1.00 81.40  ? 110 GLU C CD  1 
ATOM   7715  O OE1 . GLU C 1 110 ? -53.316 -2.774  49.257  1.00 83.83  ? 110 GLU C OE1 1 
ATOM   7716  O OE2 . GLU C 1 110 ? -52.974 -1.598  51.093  1.00 87.70  ? 110 GLU C OE2 1 
ATOM   7717  N N   . GLU C 1 111 ? -49.425 1.197   47.084  1.00 42.30  ? 111 GLU C N   1 
ATOM   7718  C CA  . GLU C 1 111 ? -48.495 1.238   45.968  1.00 44.45  ? 111 GLU C CA  1 
ATOM   7719  C C   . GLU C 1 111 ? -47.118 0.820   46.467  1.00 41.20  ? 111 GLU C C   1 
ATOM   7720  O O   . GLU C 1 111 ? -46.371 0.223   45.719  1.00 44.81  ? 111 GLU C O   1 
ATOM   7721  C CB  . GLU C 1 111 ? -48.448 2.611   45.286  1.00 52.94  ? 111 GLU C CB  1 
ATOM   7722  C CG  . GLU C 1 111 ? -47.794 2.595   43.903  1.00 63.03  ? 111 GLU C CG  1 
ATOM   7723  C CD  . GLU C 1 111 ? -48.381 1.605   42.894  1.00 80.55  ? 111 GLU C CD  1 
ATOM   7724  O OE1 . GLU C 1 111 ? -49.616 1.593   42.739  1.00 108.53 ? 111 GLU C OE1 1 
ATOM   7725  O OE2 . GLU C 1 111 ? -47.610 0.837   42.244  1.00 85.05  ? 111 GLU C OE2 1 
ATOM   7726  N N   . PHE C 1 112 ? -46.778 1.109   47.729  1.00 40.42  ? 112 PHE C N   1 
ATOM   7727  C CA  . PHE C 1 112 ? -45.483 0.709   48.268  1.00 42.42  ? 112 PHE C CA  1 
ATOM   7728  C C   . PHE C 1 112 ? -45.421 -0.803  48.461  1.00 40.96  ? 112 PHE C C   1 
ATOM   7729  O O   . PHE C 1 112 ? -44.402 -1.410  48.189  1.00 38.27  ? 112 PHE C O   1 
ATOM   7730  C CB  . PHE C 1 112 ? -45.196 1.431   49.583  1.00 44.71  ? 112 PHE C CB  1 
ATOM   7731  C CG  . PHE C 1 112 ? -44.551 2.782   49.428  1.00 47.70  ? 112 PHE C CG  1 
ATOM   7732  C CD1 . PHE C 1 112 ? -44.493 3.418   48.193  1.00 49.82  ? 112 PHE C CD1 1 
ATOM   7733  C CD2 . PHE C 1 112 ? -43.966 3.400   50.520  1.00 49.14  ? 112 PHE C CD2 1 
ATOM   7734  C CE1 . PHE C 1 112 ? -43.878 4.654   48.058  1.00 51.57  ? 112 PHE C CE1 1 
ATOM   7735  C CE2 . PHE C 1 112 ? -43.335 4.626   50.377  1.00 54.22  ? 112 PHE C CE2 1 
ATOM   7736  C CZ  . PHE C 1 112 ? -43.288 5.249   49.146  1.00 48.00  ? 112 PHE C CZ  1 
ATOM   7737  N N   . LYS C 1 113 ? -46.527 -1.393  48.917  1.00 42.84  ? 113 LYS C N   1 
ATOM   7738  C CA  . LYS C 1 113 ? -46.638 -2.828  49.110  1.00 41.58  ? 113 LYS C CA  1 
ATOM   7739  C C   . LYS C 1 113 ? -46.373 -3.572  47.807  1.00 39.31  ? 113 LYS C C   1 
ATOM   7740  O O   . LYS C 1 113 ? -45.674 -4.580  47.821  1.00 44.72  ? 113 LYS C O   1 
ATOM   7741  C CB  . LYS C 1 113 ? -47.994 -3.159  49.731  1.00 40.31  ? 113 LYS C CB  1 
ATOM   7742  C CG  . LYS C 1 113 ? -48.014 -2.875  51.226  1.00 41.55  ? 113 LYS C CG  1 
ATOM   7743  C CD  . LYS C 1 113 ? -49.384 -2.718  51.825  1.00 44.71  ? 113 LYS C CD  1 
ATOM   7744  C CE  . LYS C 1 113 ? -49.270 -2.291  53.269  1.00 49.81  ? 113 LYS C CE  1 
ATOM   7745  N NZ  . LYS C 1 113 ? -50.593 -2.045  53.884  1.00 57.48  ? 113 LYS C NZ  1 
ATOM   7746  N N   . LYS C 1 114 ? -46.856 -3.044  46.684  1.00 38.74  ? 114 LYS C N   1 
ATOM   7747  C CA  . LYS C 1 114 ? -46.629 -3.670  45.389  1.00 46.72  ? 114 LYS C CA  1 
ATOM   7748  C C   . LYS C 1 114 ? -45.149 -3.598  44.981  1.00 42.33  ? 114 LYS C C   1 
ATOM   7749  O O   . LYS C 1 114 ? -44.693 -4.389  44.172  1.00 45.76  ? 114 LYS C O   1 
ATOM   7750  C CB  . LYS C 1 114 ? -47.579 -3.059  44.348  1.00 51.24  ? 114 LYS C CB  1 
ATOM   7751  C CG  . LYS C 1 114 ? -49.035 -3.504  44.516  1.00 66.63  ? 114 LYS C CG  1 
ATOM   7752  C CD  . LYS C 1 114 ? -50.039 -2.849  43.565  1.00 71.44  ? 114 LYS C CD  1 
ATOM   7753  C CE  . LYS C 1 114 ? -49.943 -3.387  42.149  1.00 78.38  ? 114 LYS C CE  1 
ATOM   7754  N NZ  . LYS C 1 114 ? -50.395 -2.389  41.146  1.00 88.48  ? 114 LYS C NZ  1 
ATOM   7755  N N   . ARG C 1 115 ? -44.370 -2.687  45.562  1.00 38.41  ? 115 ARG C N   1 
ATOM   7756  C CA  . ARG C 1 115 ? -43.041 -2.404  45.050  1.00 40.01  ? 115 ARG C CA  1 
ATOM   7757  C C   . ARG C 1 115 ? -41.924 -2.680  46.050  1.00 35.43  ? 115 ARG C C   1 
ATOM   7758  O O   . ARG C 1 115 ? -40.801 -2.288  45.789  1.00 36.45  ? 115 ARG C O   1 
ATOM   7759  C CB  . ARG C 1 115 ? -42.955 -0.919  44.688  1.00 41.39  ? 115 ARG C CB  1 
ATOM   7760  C CG  . ARG C 1 115 ? -43.804 -0.511  43.488  1.00 39.23  ? 115 ARG C CG  1 
ATOM   7761  C CD  . ARG C 1 115 ? -43.687 1.000   43.355  1.00 43.67  ? 115 ARG C CD  1 
ATOM   7762  N NE  . ARG C 1 115 ? -44.673 1.515   42.423  1.00 49.50  ? 115 ARG C NE  1 
ATOM   7763  C CZ  . ARG C 1 115 ? -44.424 2.303   41.380  1.00 48.66  ? 115 ARG C CZ  1 
ATOM   7764  N NH1 . ARG C 1 115 ? -43.212 2.370   40.846  1.00 51.27  ? 115 ARG C NH1 1 
ATOM   7765  N NH2 . ARG C 1 115 ? -45.416 3.011   40.872  1.00 45.18  ? 115 ARG C NH2 1 
ATOM   7766  N N   . ARG C 1 116 ? -42.186 -3.304  47.193  1.00 35.72  ? 116 ARG C N   1 
ATOM   7767  C CA  . ARG C 1 116 ? -41.190 -3.280  48.260  1.00 42.12  ? 116 ARG C CA  1 
ATOM   7768  C C   . ARG C 1 116 ? -40.298 -4.531  48.256  1.00 40.79  ? 116 ARG C C   1 
ATOM   7769  O O   . ARG C 1 116 ? -39.355 -4.654  49.058  1.00 42.59  ? 116 ARG C O   1 
ATOM   7770  C CB  . ARG C 1 116 ? -41.867 -3.008  49.616  1.00 43.41  ? 116 ARG C CB  1 
ATOM   7771  C CG  . ARG C 1 116 ? -42.901 -4.026  50.064  1.00 42.57  ? 116 ARG C CG  1 
ATOM   7772  C CD  . ARG C 1 116 ? -43.082 -3.943  51.569  1.00 49.80  ? 116 ARG C CD  1 
ATOM   7773  N NE  . ARG C 1 116 ? -44.096 -3.016  52.092  1.00 49.20  ? 116 ARG C NE  1 
ATOM   7774  C CZ  . ARG C 1 116 ? -44.916 -3.301  53.115  1.00 51.61  ? 116 ARG C CZ  1 
ATOM   7775  N NH1 . ARG C 1 116 ? -45.306 -4.545  53.384  1.00 46.37  ? 116 ARG C NH1 1 
ATOM   7776  N NH2 . ARG C 1 116 ? -45.337 -2.314  53.878  1.00 50.44  ? 116 ARG C NH2 1 
ATOM   7777  N N   . ALA C 1 117 ? -40.563 -5.447  47.324  1.00 42.65  ? 117 ALA C N   1 
ATOM   7778  C CA  . ALA C 1 117 ? -39.801 -6.680  47.269  1.00 40.26  ? 117 ALA C CA  1 
ATOM   7779  C C   . ALA C 1 117 ? -38.430 -6.389  46.648  1.00 39.14  ? 117 ALA C C   1 
ATOM   7780  O O   . ALA C 1 117 ? -38.284 -5.751  45.605  1.00 40.71  ? 117 ALA C O   1 
ATOM   7781  C CB  . ALA C 1 117 ? -40.566 -7.743  46.537  1.00 36.07  ? 117 ALA C CB  1 
ATOM   7782  N N   . LEU C 1 118 ? -37.425 -6.868  47.367  1.00 41.02  ? 118 LEU C N   1 
ATOM   7783  C CA  . LEU C 1 118 ? -36.020 -6.697  47.051  1.00 42.40  ? 118 LEU C CA  1 
ATOM   7784  C C   . LEU C 1 118 ? -35.602 -7.702  45.971  1.00 39.28  ? 118 LEU C C   1 
ATOM   7785  O O   . LEU C 1 118 ? -35.876 -8.897  46.107  1.00 37.38  ? 118 LEU C O   1 
ATOM   7786  C CB  . LEU C 1 118 ? -35.306 -6.954  48.378  1.00 43.06  ? 118 LEU C CB  1 
ATOM   7787  C CG  . LEU C 1 118 ? -34.092 -6.103  48.675  1.00 45.54  ? 118 LEU C CG  1 
ATOM   7788  C CD1 . LEU C 1 118 ? -34.510 -4.654  48.683  1.00 47.41  ? 118 LEU C CD1 1 
ATOM   7789  C CD2 . LEU C 1 118 ? -33.480 -6.532  50.004  1.00 44.36  ? 118 LEU C CD2 1 
ATOM   7790  N N   . PRO C 1 119 ? -34.949 -7.281  44.861  1.00 37.03  ? 119 PRO C N   1 
ATOM   7791  C CA  . PRO C 1 119 ? -34.426 -8.225  43.869  1.00 38.03  ? 119 PRO C CA  1 
ATOM   7792  C C   . PRO C 1 119 ? -33.515 -9.269  44.491  1.00 35.62  ? 119 PRO C C   1 
ATOM   7793  O O   . PRO C 1 119 ? -32.713 -8.924  45.348  1.00 40.08  ? 119 PRO C O   1 
ATOM   7794  C CB  . PRO C 1 119 ? -33.591 -7.337  42.930  1.00 39.45  ? 119 PRO C CB  1 
ATOM   7795  C CG  . PRO C 1 119 ? -34.305 -6.019  43.002  1.00 36.54  ? 119 PRO C CG  1 
ATOM   7796  C CD  . PRO C 1 119 ? -34.696 -5.893  44.469  1.00 36.07  ? 119 PRO C CD  1 
ATOM   7797  N N   . GLU C 1 120 ? -33.646 -10.531 44.070  1.00 37.64  ? 120 GLU C N   1 
ATOM   7798  C CA  . GLU C 1 120 ? -32.731 -11.573 44.505  1.00 39.41  ? 120 GLU C CA  1 
ATOM   7799  C C   . GLU C 1 120 ? -31.265 -11.193 44.297  1.00 34.36  ? 120 GLU C C   1 
ATOM   7800  O O   . GLU C 1 120 ? -30.462 -11.423 45.191  1.00 34.68  ? 120 GLU C O   1 
ATOM   7801  C CB  . GLU C 1 120 ? -33.039 -12.895 43.815  1.00 44.06  ? 120 GLU C CB  1 
ATOM   7802  C CG  . GLU C 1 120 ? -34.154 -13.642 44.506  1.00 57.17  ? 120 GLU C CG  1 
ATOM   7803  C CD  . GLU C 1 120 ? -33.900 -13.859 45.996  1.00 67.00  ? 120 GLU C CD  1 
ATOM   7804  O OE1 . GLU C 1 120 ? -32.840 -14.474 46.360  1.00 52.84  ? 120 GLU C OE1 1 
ATOM   7805  O OE2 . GLU C 1 120 ? -34.745 -13.379 46.795  1.00 72.16  ? 120 GLU C OE2 1 
ATOM   7806  N N   . TYR C 1 121 ? -30.911 -10.610 43.145  1.00 32.11  ? 121 TYR C N   1 
ATOM   7807  C CA  . TYR C 1 121 ? -29.506 -10.335 42.847  1.00 30.41  ? 121 TYR C CA  1 
ATOM   7808  C C   . TYR C 1 121 ? -28.912 -9.309  43.814  1.00 29.31  ? 121 TYR C C   1 
ATOM   7809  O O   . TYR C 1 121 ? -27.712 -9.278  43.968  1.00 28.37  ? 121 TYR C O   1 
ATOM   7810  C CB  . TYR C 1 121 ? -29.301 -9.884  41.405  1.00 28.63  ? 121 TYR C CB  1 
ATOM   7811  C CG  . TYR C 1 121 ? -29.952 -8.565  41.039  1.00 30.14  ? 121 TYR C CG  1 
ATOM   7812  C CD1 . TYR C 1 121 ? -29.401 -7.348  41.436  1.00 32.00  ? 121 TYR C CD1 1 
ATOM   7813  C CD2 . TYR C 1 121 ? -31.083 -8.536  40.242  1.00 25.84  ? 121 TYR C CD2 1 
ATOM   7814  C CE1 . TYR C 1 121 ? -29.996 -6.146  41.079  1.00 31.70  ? 121 TYR C CE1 1 
ATOM   7815  C CE2 . TYR C 1 121 ? -31.696 -7.348  39.886  1.00 27.42  ? 121 TYR C CE2 1 
ATOM   7816  C CZ  . TYR C 1 121 ? -31.145 -6.154  40.296  1.00 29.71  ? 121 TYR C CZ  1 
ATOM   7817  O OH  . TYR C 1 121 ? -31.746 -4.990  39.932  1.00 31.65  ? 121 TYR C OH  1 
ATOM   7818  N N   . VAL C 1 122 ? -29.743 -8.479  44.458  1.00 32.86  ? 122 VAL C N   1 
ATOM   7819  C CA  . VAL C 1 122 ? -29.277 -7.539  45.468  1.00 30.92  ? 122 VAL C CA  1 
ATOM   7820  C C   . VAL C 1 122 ? -28.813 -8.297  46.703  1.00 34.43  ? 122 VAL C C   1 
ATOM   7821  O O   . VAL C 1 122 ? -27.788 -7.986  47.278  1.00 41.03  ? 122 VAL C O   1 
ATOM   7822  C CB  . VAL C 1 122 ? -30.348 -6.506  45.846  1.00 29.57  ? 122 VAL C CB  1 
ATOM   7823  C CG1 . VAL C 1 122 ? -29.939 -5.751  47.110  1.00 32.41  ? 122 VAL C CG1 1 
ATOM   7824  C CG2 . VAL C 1 122 ? -30.644 -5.540  44.700  1.00 29.48  ? 122 VAL C CG2 1 
ATOM   7825  N N   . LYS C 1 123 ? -29.593 -9.271  47.145  1.00 36.52  ? 123 LYS C N   1 
ATOM   7826  C CA  . LYS C 1 123 ? -29.152 -10.137 48.222  1.00 36.27  ? 123 LYS C CA  1 
ATOM   7827  C C   . LYS C 1 123 ? -27.857 -10.888 47.854  1.00 36.62  ? 123 LYS C C   1 
ATOM   7828  O O   . LYS C 1 123 ? -26.928 -10.976 48.673  1.00 31.19  ? 123 LYS C O   1 
ATOM   7829  C CB  . LYS C 1 123 ? -30.294 -11.096 48.527  1.00 33.81  ? 123 LYS C CB  1 
ATOM   7830  C CG  . LYS C 1 123 ? -31.575 -10.416 48.954  1.00 37.37  ? 123 LYS C CG  1 
ATOM   7831  C CD  . LYS C 1 123 ? -32.679 -11.413 49.115  1.00 44.00  ? 123 LYS C CD  1 
ATOM   7832  C CE  . LYS C 1 123 ? -34.033 -10.775 49.256  1.00 47.16  ? 123 LYS C CE  1 
ATOM   7833  N NZ  . LYS C 1 123 ? -35.060 -11.818 49.381  1.00 55.27  ? 123 LYS C NZ  1 
ATOM   7834  N N   . ASP C 1 124 ? -27.800 -11.451 46.636  1.00 34.88  ? 124 ASP C N   1 
ATOM   7835  C CA  . ASP C 1 124 ? -26.606 -12.127 46.160  1.00 38.99  ? 124 ASP C CA  1 
ATOM   7836  C C   . ASP C 1 124 ? -25.395 -11.203 46.244  1.00 35.15  ? 124 ASP C C   1 
ATOM   7837  O O   . ASP C 1 124 ? -24.310 -11.625 46.632  1.00 32.86  ? 124 ASP C O   1 
ATOM   7838  C CB  . ASP C 1 124 ? -26.726 -12.545 44.693  1.00 47.26  ? 124 ASP C CB  1 
ATOM   7839  C CG  . ASP C 1 124 ? -27.875 -13.491 44.371  1.00 58.26  ? 124 ASP C CG  1 
ATOM   7840  O OD1 . ASP C 1 124 ? -28.356 -14.198 45.337  1.00 56.69  ? 124 ASP C OD1 1 
ATOM   7841  O OD2 . ASP C 1 124 ? -28.294 -13.496 43.151  1.00 52.91  ? 124 ASP C OD2 1 
ATOM   7842  N N   . THR C 1 125 ? -25.590 -9.956  45.824  1.00 29.59  ? 125 THR C N   1 
ATOM   7843  C CA  . THR C 1 125 ? -24.517 -8.981  45.783  1.00 34.37  ? 125 THR C CA  1 
ATOM   7844  C C   . THR C 1 125 ? -23.985 -8.712  47.198  1.00 34.02  ? 125 THR C C   1 
ATOM   7845  O O   . THR C 1 125 ? -22.786 -8.811  47.408  1.00 33.47  ? 125 THR C O   1 
ATOM   7846  C CB  . THR C 1 125 ? -24.994 -7.700  45.077  1.00 35.57  ? 125 THR C CB  1 
ATOM   7847  O OG1 . THR C 1 125 ? -25.221 -8.060  43.714  1.00 43.21  ? 125 THR C OG1 1 
ATOM   7848  C CG2 . THR C 1 125 ? -24.028 -6.538  45.109  1.00 37.38  ? 125 THR C CG2 1 
ATOM   7849  N N   . LEU C 1 126 ? -24.881 -8.387  48.139  1.00 30.52  ? 126 LEU C N   1 
ATOM   7850  C CA  . LEU C 1 126 ? -24.523 -8.114  49.513  1.00 32.66  ? 126 LEU C CA  1 
ATOM   7851  C C   . LEU C 1 126 ? -23.832 -9.295  50.210  1.00 35.75  ? 126 LEU C C   1 
ATOM   7852  O O   . LEU C 1 126 ? -23.052 -9.088  51.138  1.00 28.21  ? 126 LEU C O   1 
ATOM   7853  C CB  . LEU C 1 126 ? -25.806 -7.789  50.267  1.00 33.98  ? 126 LEU C CB  1 
ATOM   7854  C CG  . LEU C 1 126 ? -26.529 -6.495  49.895  1.00 33.26  ? 126 LEU C CG  1 
ATOM   7855  C CD1 . LEU C 1 126 ? -27.688 -6.302  50.880  1.00 35.42  ? 126 LEU C CD1 1 
ATOM   7856  C CD2 . LEU C 1 126 ? -25.597 -5.287  49.889  1.00 37.71  ? 126 LEU C CD2 1 
ATOM   7857  N N   . LYS C 1 127 ? -24.143 -10.530 49.810  1.00 36.28  ? 127 LYS C N   1 
ATOM   7858  C CA  . LYS C 1 127 ? -23.447 -11.686 50.355  1.00 42.80  ? 127 LYS C CA  1 
ATOM   7859  C C   . LYS C 1 127 ? -22.036 -11.811 49.774  1.00 41.94  ? 127 LYS C C   1 
ATOM   7860  O O   . LYS C 1 127 ? -21.126 -12.303 50.447  1.00 39.32  ? 127 LYS C O   1 
ATOM   7861  C CB  . LYS C 1 127 ? -24.139 -12.998 49.972  1.00 44.67  ? 127 LYS C CB  1 
ATOM   7862  C CG  . LYS C 1 127 ? -25.501 -13.282 50.569  1.00 44.10  ? 127 LYS C CG  1 
ATOM   7863  C CD  . LYS C 1 127 ? -26.009 -14.581 49.993  1.00 47.94  ? 127 LYS C CD  1 
ATOM   7864  C CE  . LYS C 1 127 ? -27.475 -14.845 50.226  1.00 47.99  ? 127 LYS C CE  1 
ATOM   7865  N NZ  . LYS C 1 127 ? -27.816 -16.185 49.701  1.00 52.01  ? 127 LYS C NZ  1 
ATOM   7866  N N   . ALA C 1 128 ? -21.897 -11.463 48.488  1.00 35.97  ? 128 ALA C N   1 
ATOM   7867  C CA  . ALA C 1 128 ? -20.615 -11.547 47.805  1.00 34.88  ? 128 ALA C CA  1 
ATOM   7868  C C   . ALA C 1 128 ? -19.635 -10.533 48.391  1.00 34.47  ? 128 ALA C C   1 
ATOM   7869  O O   . ALA C 1 128 ? -18.433 -10.759 48.399  1.00 41.46  ? 128 ALA C O   1 
ATOM   7870  C CB  . ALA C 1 128 ? -20.802 -11.345 46.315  1.00 31.21  ? 128 ALA C CB  1 
ATOM   7871  N N   . MET C 1 129 ? -20.156 -9.399  48.842  1.00 35.42  ? 129 MET C N   1 
ATOM   7872  C CA  . MET C 1 129 ? -19.365 -8.410  49.561  1.00 41.32  ? 129 MET C CA  1 
ATOM   7873  C C   . MET C 1 129 ? -19.012 -8.978  50.928  1.00 36.93  ? 129 MET C C   1 
ATOM   7874  O O   . MET C 1 129 ? -19.886 -9.488  51.626  1.00 41.29  ? 129 MET C O   1 
ATOM   7875  C CB  . MET C 1 129 ? -20.163 -7.125  49.797  1.00 42.17  ? 129 MET C CB  1 
ATOM   7876  C CG  . MET C 1 129 ? -20.408 -6.302  48.532  1.00 46.74  ? 129 MET C CG  1 
ATOM   7877  S SD  . MET C 1 129 ? -21.490 -4.892  48.901  1.00 48.01  ? 129 MET C SD  1 
ATOM   7878  C CE  . MET C 1 129 ? -20.255 -3.625  49.189  1.00 51.19  ? 129 MET C CE  1 
ATOM   7879  N N   . PRO C 1 130 ? -17.747 -8.867  51.373  1.00 30.87  ? 130 PRO C N   1 
ATOM   7880  C CA  . PRO C 1 130 ? -17.352 -9.404  52.674  1.00 28.69  ? 130 PRO C CA  1 
ATOM   7881  C C   . PRO C 1 130 ? -18.278 -8.921  53.780  1.00 28.50  ? 130 PRO C C   1 
ATOM   7882  O O   . PRO C 1 130 ? -18.686 -7.779  53.796  1.00 30.47  ? 130 PRO C O   1 
ATOM   7883  C CB  . PRO C 1 130 ? -15.948 -8.822  52.847  1.00 30.73  ? 130 PRO C CB  1 
ATOM   7884  C CG  . PRO C 1 130 ? -15.436 -8.675  51.434  1.00 28.54  ? 130 PRO C CG  1 
ATOM   7885  C CD  . PRO C 1 130 ? -16.648 -8.190  50.666  1.00 29.93  ? 130 PRO C CD  1 
ATOM   7886  N N   . ARG C 1 131 ? -18.623 -9.812  54.695  1.00 32.50  ? 131 ARG C N   1 
ATOM   7887  C CA  . ARG C 1 131 ? -19.652 -9.558  55.687  1.00 33.61  ? 131 ARG C CA  1 
ATOM   7888  C C   . ARG C 1 131 ? -19.202 -8.491  56.673  1.00 36.27  ? 131 ARG C C   1 
ATOM   7889  O O   . ARG C 1 131 ? -20.043 -7.924  57.347  1.00 40.39  ? 131 ARG C O   1 
ATOM   7890  C CB  . ARG C 1 131 ? -19.972 -10.856 56.438  1.00 36.31  ? 131 ARG C CB  1 
ATOM   7891  C CG  . ARG C 1 131 ? -21.164 -10.758 57.380  1.00 36.50  ? 131 ARG C CG  1 
ATOM   7892  C CD  . ARG C 1 131 ? -22.442 -10.487 56.623  1.00 35.74  ? 131 ARG C CD  1 
ATOM   7893  N NE  . ARG C 1 131 ? -22.612 -11.522 55.604  1.00 37.72  ? 131 ARG C NE  1 
ATOM   7894  C CZ  . ARG C 1 131 ? -23.499 -12.519 55.659  1.00 36.11  ? 131 ARG C CZ  1 
ATOM   7895  N NH1 . ARG C 1 131 ? -24.245 -12.716 56.739  1.00 35.26  ? 131 ARG C NH1 1 
ATOM   7896  N NH2 . ARG C 1 131 ? -23.678 -13.282 54.598  1.00 32.80  ? 131 ARG C NH2 1 
ATOM   7897  N N   . ASP C 1 132 ? -17.887 -8.234  56.777  1.00 38.77  ? 132 ASP C N   1 
ATOM   7898  C CA  . ASP C 1 132 ? -17.338 -7.224  57.689  1.00 37.77  ? 132 ASP C CA  1 
ATOM   7899  C C   . ASP C 1 132 ? -17.279 -5.821  57.047  1.00 34.86  ? 132 ASP C C   1 
ATOM   7900  O O   . ASP C 1 132 ? -16.682 -4.902  57.599  1.00 38.46  ? 132 ASP C O   1 
ATOM   7901  C CB  . ASP C 1 132 ? -15.917 -7.604  58.149  1.00 38.14  ? 132 ASP C CB  1 
ATOM   7902  C CG  . ASP C 1 132 ? -14.894 -7.842  57.031  1.00 39.58  ? 132 ASP C CG  1 
ATOM   7903  O OD1 . ASP C 1 132 ? -15.247 -7.662  55.860  1.00 51.31  ? 132 ASP C OD1 1 
ATOM   7904  O OD2 . ASP C 1 132 ? -13.748 -8.193  57.323  1.00 36.13  ? 132 ASP C OD2 1 
ATOM   7905  N N   . THR C 1 133 ? -17.823 -5.665  55.838  1.00 35.40  ? 133 THR C N   1 
ATOM   7906  C CA  . THR C 1 133 ? -18.036 -4.372  55.204  1.00 34.83  ? 133 THR C CA  1 
ATOM   7907  C C   . THR C 1 133 ? -18.959 -3.491  56.057  1.00 37.79  ? 133 THR C C   1 
ATOM   7908  O O   . THR C 1 133 ? -19.943 -3.945  56.657  1.00 36.23  ? 133 THR C O   1 
ATOM   7909  C CB  . THR C 1 133 ? -18.585 -4.615  53.800  1.00 34.28  ? 133 THR C CB  1 
ATOM   7910  O OG1 . THR C 1 133 ? -17.603 -5.375  53.089  1.00 34.89  ? 133 THR C OG1 1 
ATOM   7911  C CG2 . THR C 1 133 ? -18.878 -3.343  53.053  1.00 38.02  ? 133 THR C CG2 1 
ATOM   7912  N N   . HIS C 1 134 ? -18.613 -2.201  56.133  1.00 41.41  ? 134 HIS C N   1 
ATOM   7913  C CA  . HIS C 1 134 ? -19.417 -1.229  56.849  1.00 39.04  ? 134 HIS C CA  1 
ATOM   7914  C C   . HIS C 1 134 ? -20.824 -1.247  56.242  1.00 34.77  ? 134 HIS C C   1 
ATOM   7915  O O   . HIS C 1 134 ? -20.969 -1.346  55.024  1.00 34.54  ? 134 HIS C O   1 
ATOM   7916  C CB  . HIS C 1 134 ? -18.733 0.146   56.800  1.00 45.16  ? 134 HIS C CB  1 
ATOM   7917  C CG  . HIS C 1 134 ? -19.409 1.191   57.634  1.00 60.01  ? 134 HIS C CG  1 
ATOM   7918  N ND1 . HIS C 1 134 ? -20.560 1.866   57.252  1.00 65.61  ? 134 HIS C ND1 1 
ATOM   7919  C CD2 . HIS C 1 134 ? -19.062 1.660   58.867  1.00 68.75  ? 134 HIS C CD2 1 
ATOM   7920  C CE1 . HIS C 1 134 ? -20.930 2.703   58.222  1.00 64.62  ? 134 HIS C CE1 1 
ATOM   7921  N NE2 . HIS C 1 134 ? -20.005 2.591   59.238  1.00 80.64  ? 134 HIS C NE2 1 
ATOM   7922  N N   . PRO C 1 135 ? -21.912 -1.218  57.051  1.00 30.57  ? 135 PRO C N   1 
ATOM   7923  C CA  . PRO C 1 135 ? -23.268 -1.300  56.522  1.00 32.72  ? 135 PRO C CA  1 
ATOM   7924  C C   . PRO C 1 135 ? -23.652 -0.216  55.520  1.00 31.27  ? 135 PRO C C   1 
ATOM   7925  O O   . PRO C 1 135 ? -24.477 -0.457  54.656  1.00 31.62  ? 135 PRO C O   1 
ATOM   7926  C CB  . PRO C 1 135 ? -24.167 -1.186  57.762  1.00 35.18  ? 135 PRO C CB  1 
ATOM   7927  C CG  . PRO C 1 135 ? -23.289 -0.603  58.834  1.00 35.23  ? 135 PRO C CG  1 
ATOM   7928  C CD  . PRO C 1 135 ? -21.915 -1.145  58.518  1.00 33.97  ? 135 PRO C CD  1 
ATOM   7929  N N   . MET C 1 136 ? -23.069 0.969   55.645  1.00 32.64  ? 136 MET C N   1 
ATOM   7930  C CA  . MET C 1 136 ? -23.362 2.029   54.699  1.00 39.40  ? 136 MET C CA  1 
ATOM   7931  C C   . MET C 1 136 ? -22.745 1.723   53.331  1.00 42.10  ? 136 MET C C   1 
ATOM   7932  O O   . MET C 1 136 ? -23.260 2.185   52.314  1.00 39.99  ? 136 MET C O   1 
ATOM   7933  C CB  . MET C 1 136 ? -22.884 3.386   55.211  1.00 37.68  ? 136 MET C CB  1 
ATOM   7934  C CG  . MET C 1 136 ? -23.898 4.048   56.140  1.00 41.45  ? 136 MET C CG  1 
ATOM   7935  S SD  . MET C 1 136 ? -25.488 4.579   55.408  1.00 39.29  ? 136 MET C SD  1 
ATOM   7936  C CE  . MET C 1 136 ? -24.969 5.473   53.950  1.00 42.79  ? 136 MET C CE  1 
ATOM   7937  N N   . THR C 1 137 ? -21.667 0.929   53.296  1.00 42.55  ? 137 THR C N   1 
ATOM   7938  C CA  . THR C 1 137 ? -21.110 0.509   52.016  1.00 39.17  ? 137 THR C CA  1 
ATOM   7939  C C   . THR C 1 137 ? -22.097 -0.463  51.379  1.00 35.22  ? 137 THR C C   1 
ATOM   7940  O O   . THR C 1 137 ? -22.449 -0.321  50.209  1.00 31.23  ? 137 THR C O   1 
ATOM   7941  C CB  . THR C 1 137 ? -19.710 -0.104  52.169  1.00 39.69  ? 137 THR C CB  1 
ATOM   7942  O OG1 . THR C 1 137 ? -18.891 0.799   52.904  1.00 35.83  ? 137 THR C OG1 1 
ATOM   7943  C CG2 . THR C 1 137 ? -19.032 -0.420  50.850  1.00 39.20  ? 137 THR C CG2 1 
ATOM   7944  N N   . MET C 1 138 ? -22.605 -1.392  52.193  1.00 31.50  ? 138 MET C N   1 
ATOM   7945  C CA  . MET C 1 138 ? -23.574 -2.352  51.701  1.00 34.61  ? 138 MET C CA  1 
ATOM   7946  C C   . MET C 1 138 ? -24.845 -1.660  51.226  1.00 33.32  ? 138 MET C C   1 
ATOM   7947  O O   . MET C 1 138 ? -25.350 -1.956  50.156  1.00 32.00  ? 138 MET C O   1 
ATOM   7948  C CB  . MET C 1 138 ? -23.911 -3.344  52.800  1.00 38.71  ? 138 MET C CB  1 
ATOM   7949  C CG  . MET C 1 138 ? -22.886 -4.427  52.893  1.00 43.38  ? 138 MET C CG  1 
ATOM   7950  S SD  . MET C 1 138 ? -23.240 -5.494  54.327  1.00 54.55  ? 138 MET C SD  1 
ATOM   7951  C CE  . MET C 1 138 ? -22.040 -6.791  54.010  1.00 57.37  ? 138 MET C CE  1 
ATOM   7952  N N   . PHE C 1 139 ? -25.342 -0.717  52.015  1.00 34.11  ? 139 PHE C N   1 
ATOM   7953  C CA  . PHE C 1 139 ? -26.519 0.055   51.650  1.00 32.79  ? 139 PHE C CA  1 
ATOM   7954  C C   . PHE C 1 139 ? -26.387 0.722   50.281  1.00 32.44  ? 139 PHE C C   1 
ATOM   7955  O O   . PHE C 1 139 ? -27.251 0.543   49.416  1.00 28.12  ? 139 PHE C O   1 
ATOM   7956  C CB  . PHE C 1 139 ? -26.764 1.124   52.714  1.00 32.42  ? 139 PHE C CB  1 
ATOM   7957  C CG  . PHE C 1 139 ? -28.136 1.740   52.670  1.00 31.83  ? 139 PHE C CG  1 
ATOM   7958  C CD1 . PHE C 1 139 ? -29.267 0.944   52.707  1.00 32.39  ? 139 PHE C CD1 1 
ATOM   7959  C CD2 . PHE C 1 139 ? -28.302 3.111   52.629  1.00 31.50  ? 139 PHE C CD2 1 
ATOM   7960  C CE1 . PHE C 1 139 ? -30.536 1.506   52.702  1.00 34.75  ? 139 PHE C CE1 1 
ATOM   7961  C CE2 . PHE C 1 139 ? -29.569 3.663   52.589  1.00 33.82  ? 139 PHE C CE2 1 
ATOM   7962  C CZ  . PHE C 1 139 ? -30.682 2.859   52.638  1.00 32.00  ? 139 PHE C CZ  1 
ATOM   7963  N N   . ALA C 1 140 ? -25.301 1.498   50.103  1.00 31.40  ? 140 ALA C N   1 
ATOM   7964  C CA  . ALA C 1 140 ? -25.045 2.240   48.873  1.00 28.29  ? 140 ALA C CA  1 
ATOM   7965  C C   . ALA C 1 140 ? -24.914 1.298   47.671  1.00 28.31  ? 140 ALA C C   1 
ATOM   7966  O O   . ALA C 1 140 ? -25.404 1.585   46.588  1.00 28.77  ? 140 ALA C O   1 
ATOM   7967  C CB  . ALA C 1 140 ? -23.807 3.102   49.051  1.00 29.43  ? 140 ALA C CB  1 
ATOM   7968  N N   . ALA C 1 141 ? -24.256 0.152   47.857  1.00 30.57  ? 141 ALA C N   1 
ATOM   7969  C CA  . ALA C 1 141 ? -24.092 -0.825  46.789  1.00 28.62  ? 141 ALA C CA  1 
ATOM   7970  C C   . ALA C 1 141 ? -25.393 -1.567  46.475  1.00 33.49  ? 141 ALA C C   1 
ATOM   7971  O O   . ALA C 1 141 ? -25.587 -2.012  45.352  1.00 30.20  ? 141 ALA C O   1 
ATOM   7972  C CB  . ALA C 1 141 ? -23.048 -1.818  47.204  1.00 30.85  ? 141 ALA C CB  1 
ATOM   7973  N N   . GLY C 1 142 ? -26.270 -1.788  47.469  1.00 38.42  ? 142 GLY C N   1 
ATOM   7974  C CA  . GLY C 1 142 ? -27.567 -2.386  47.202  1.00 38.31  ? 142 GLY C CA  1 
ATOM   7975  C C   . GLY C 1 142 ? -28.397 -1.500  46.278  1.00 41.03  ? 142 GLY C C   1 
ATOM   7976  O O   . GLY C 1 142 ? -29.101 -2.004  45.395  1.00 39.44  ? 142 GLY C O   1 
ATOM   7977  N N   . ILE C 1 143 ? -28.299 -0.181  46.500  1.00 37.95  ? 143 ILE C N   1 
ATOM   7978  C CA  . ILE C 1 143 ? -29.023 0.806   45.716  1.00 35.12  ? 143 ILE C CA  1 
ATOM   7979  C C   . ILE C 1 143 ? -28.468 0.797   44.303  1.00 38.61  ? 143 ILE C C   1 
ATOM   7980  O O   . ILE C 1 143 ? -29.200 0.715   43.314  1.00 33.40  ? 143 ILE C O   1 
ATOM   7981  C CB  . ILE C 1 143 ? -28.852 2.202   46.341  1.00 33.43  ? 143 ILE C CB  1 
ATOM   7982  C CG1 . ILE C 1 143 ? -29.475 2.282   47.735  1.00 33.56  ? 143 ILE C CG1 1 
ATOM   7983  C CG2 . ILE C 1 143 ? -29.385 3.273   45.414  1.00 35.33  ? 143 ILE C CG2 1 
ATOM   7984  C CD1 . ILE C 1 143 ? -28.996 3.458   48.557  1.00 33.95  ? 143 ILE C CD1 1 
ATOM   7985  N N   . LEU C 1 144 ? -27.144 0.942   44.242  1.00 35.94  ? 144 LEU C N   1 
ATOM   7986  C CA  . LEU C 1 144 ? -26.403 1.007   42.988  1.00 35.60  ? 144 LEU C CA  1 
ATOM   7987  C C   . LEU C 1 144 ? -26.720 -0.182  42.074  1.00 32.80  ? 144 LEU C C   1 
ATOM   7988  O O   . LEU C 1 144 ? -26.913 -0.009  40.878  1.00 34.75  ? 144 LEU C O   1 
ATOM   7989  C CB  . LEU C 1 144 ? -24.914 1.056   43.354  1.00 32.78  ? 144 LEU C CB  1 
ATOM   7990  C CG  . LEU C 1 144 ? -23.959 1.263   42.195  1.00 34.30  ? 144 LEU C CG  1 
ATOM   7991  C CD1 . LEU C 1 144 ? -24.454 2.378   41.280  1.00 34.80  ? 144 LEU C CD1 1 
ATOM   7992  C CD2 . LEU C 1 144 ? -22.562 1.582   42.726  1.00 37.13  ? 144 LEU C CD2 1 
ATOM   7993  N N   . ALA C 1 145 ? -26.731 -1.396  42.640  1.00 34.55  ? 145 ALA C N   1 
ATOM   7994  C CA  . ALA C 1 145 ? -26.980 -2.626  41.905  1.00 33.61  ? 145 ALA C CA  1 
ATOM   7995  C C   . ALA C 1 145 ? -28.348 -2.589  41.219  1.00 37.01  ? 145 ALA C C   1 
ATOM   7996  O O   . ALA C 1 145 ? -28.491 -3.157  40.148  1.00 42.43  ? 145 ALA C O   1 
ATOM   7997  C CB  . ALA C 1 145 ? -26.886 -3.796  42.836  1.00 32.12  ? 145 ALA C CB  1 
ATOM   7998  N N   . MET C 1 146 ? -29.326 -1.903  41.830  1.00 35.49  ? 146 MET C N   1 
ATOM   7999  C CA  . MET C 1 146 ? -30.697 -1.820  41.344  1.00 32.43  ? 146 MET C CA  1 
ATOM   8000  C C   . MET C 1 146 ? -30.863 -0.796  40.224  1.00 31.73  ? 146 MET C C   1 
ATOM   8001  O O   . MET C 1 146 ? -31.956 -0.655  39.688  1.00 32.51  ? 146 MET C O   1 
ATOM   8002  C CB  . MET C 1 146 ? -31.619 -1.435  42.501  1.00 33.00  ? 146 MET C CB  1 
ATOM   8003  C CG  . MET C 1 146 ? -31.976 -2.634  43.355  1.00 36.19  ? 146 MET C CG  1 
ATOM   8004  S SD  . MET C 1 146 ? -33.134 -2.276  44.703  1.00 36.25  ? 146 MET C SD  1 
ATOM   8005  C CE  . MET C 1 146 ? -32.324 -1.031  45.692  1.00 39.78  ? 146 MET C CE  1 
ATOM   8006  N N   . GLN C 1 147 ? -29.784 -0.103  39.860  1.00 31.00  ? 147 GLN C N   1 
ATOM   8007  C CA  . GLN C 1 147 ? -29.770 0.821   38.730  1.00 33.63  ? 147 GLN C CA  1 
ATOM   8008  C C   . GLN C 1 147 ? -30.151 0.099   37.440  1.00 35.27  ? 147 GLN C C   1 
ATOM   8009  O O   . GLN C 1 147 ? -30.668 0.724   36.514  1.00 39.52  ? 147 GLN C O   1 
ATOM   8010  C CB  . GLN C 1 147 ? -28.378 1.450   38.612  1.00 30.71  ? 147 GLN C CB  1 
ATOM   8011  C CG  . GLN C 1 147 ? -28.281 2.580   37.594  1.00 31.23  ? 147 GLN C CG  1 
ATOM   8012  C CD  . GLN C 1 147 ? -28.077 2.086   36.180  1.00 30.57  ? 147 GLN C CD  1 
ATOM   8013  O OE1 . GLN C 1 147 ? -27.359 1.114   35.948  1.00 31.01  ? 147 GLN C OE1 1 
ATOM   8014  N NE2 . GLN C 1 147 ? -28.739 2.726   35.224  1.00 27.75  ? 147 GLN C NE2 1 
ATOM   8015  N N   . ARG C 1 148 ? -29.867 -1.211  37.385  1.00 35.27  ? 148 ARG C N   1 
ATOM   8016  C CA  . ARG C 1 148 ? -30.303 -2.093  36.306  1.00 37.37  ? 148 ARG C CA  1 
ATOM   8017  C C   . ARG C 1 148 ? -31.797 -1.959  35.985  1.00 34.78  ? 148 ARG C C   1 
ATOM   8018  O O   . ARG C 1 148 ? -32.186 -2.235  34.869  1.00 27.46  ? 148 ARG C O   1 
ATOM   8019  C CB  . ARG C 1 148 ? -30.017 -3.547  36.695  1.00 42.70  ? 148 ARG C CB  1 
ATOM   8020  C CG  . ARG C 1 148 ? -30.372 -4.592  35.640  1.00 44.90  ? 148 ARG C CG  1 
ATOM   8021  C CD  . ARG C 1 148 ? -30.093 -5.959  36.223  1.00 42.97  ? 148 ARG C CD  1 
ATOM   8022  N NE  . ARG C 1 148 ? -30.569 -7.042  35.379  1.00 43.12  ? 148 ARG C NE  1 
ATOM   8023  C CZ  . ARG C 1 148 ? -31.831 -7.430  35.261  1.00 37.54  ? 148 ARG C CZ  1 
ATOM   8024  N NH1 . ARG C 1 148 ? -32.801 -6.890  35.972  1.00 38.20  ? 148 ARG C NH1 1 
ATOM   8025  N NH2 . ARG C 1 148 ? -32.114 -8.366  34.393  1.00 39.83  ? 148 ARG C NH2 1 
ATOM   8026  N N   . GLU C 1 149 ? -32.627 -1.576  36.972  1.00 41.73  ? 149 GLU C N   1 
ATOM   8027  C CA  . GLU C 1 149 ? -34.075 -1.518  36.832  1.00 43.49  ? 149 GLU C CA  1 
ATOM   8028  C C   . GLU C 1 149 ? -34.584 -0.108  36.520  1.00 43.18  ? 149 GLU C C   1 
ATOM   8029  O O   . GLU C 1 149 ? -35.786 0.140   36.596  1.00 47.50  ? 149 GLU C O   1 
ATOM   8030  C CB  . GLU C 1 149 ? -34.731 -1.931  38.152  1.00 47.77  ? 149 GLU C CB  1 
ATOM   8031  C CG  . GLU C 1 149 ? -34.160 -3.200  38.767  1.00 57.49  ? 149 GLU C CG  1 
ATOM   8032  C CD  . GLU C 1 149 ? -34.143 -4.437  37.873  1.00 57.83  ? 149 GLU C CD  1 
ATOM   8033  O OE1 . GLU C 1 149 ? -34.859 -4.442  36.836  1.00 52.42  ? 149 GLU C OE1 1 
ATOM   8034  O OE2 . GLU C 1 149 ? -33.376 -5.391  38.205  1.00 57.49  ? 149 GLU C OE2 1 
ATOM   8035  N N   . SER C 1 150 ? -33.672 0.828   36.238  1.00 42.78  ? 150 SER C N   1 
ATOM   8036  C CA  . SER C 1 150 ? -34.036 2.233   36.172  1.00 38.00  ? 150 SER C CA  1 
ATOM   8037  C C   . SER C 1 150 ? -34.921 2.463   34.958  1.00 38.72  ? 150 SER C C   1 
ATOM   8038  O O   . SER C 1 150 ? -34.556 2.103   33.840  1.00 38.10  ? 150 SER C O   1 
ATOM   8039  C CB  . SER C 1 150 ? -32.817 3.135   36.143  1.00 36.33  ? 150 SER C CB  1 
ATOM   8040  O OG  . SER C 1 150 ? -33.206 4.491   35.923  1.00 29.96  ? 150 SER C OG  1 
ATOM   8041  N N   . LYS C 1 151 ? -36.078 3.086   35.209  1.00 44.16  ? 151 LYS C N   1 
ATOM   8042  C CA  . LYS C 1 151 ? -37.044 3.422   34.171  1.00 47.20  ? 151 LYS C CA  1 
ATOM   8043  C C   . LYS C 1 151 ? -36.566 4.660   33.441  1.00 42.60  ? 151 LYS C C   1 
ATOM   8044  O O   . LYS C 1 151 ? -36.646 4.734   32.216  1.00 35.80  ? 151 LYS C O   1 
ATOM   8045  C CB  . LYS C 1 151 ? -38.426 3.637   34.798  1.00 50.48  ? 151 LYS C CB  1 
ATOM   8046  C CG  . LYS C 1 151 ? -39.217 2.346   34.922  1.00 54.18  ? 151 LYS C CG  1 
ATOM   8047  C CD  . LYS C 1 151 ? -39.805 2.066   36.260  1.00 57.03  ? 151 LYS C CD  1 
ATOM   8048  C CE  . LYS C 1 151 ? -40.028 0.576   36.408  1.00 60.79  ? 151 LYS C CE  1 
ATOM   8049  N NZ  . LYS C 1 151 ? -40.730 0.296   37.681  1.00 67.21  ? 151 LYS C NZ  1 
ATOM   8050  N N   . PHE C 1 152 ? -36.055 5.607   34.236  1.00 40.26  ? 152 PHE C N   1 
ATOM   8051  C CA  . PHE C 1 152 ? -35.445 6.795   33.692  1.00 41.42  ? 152 PHE C CA  1 
ATOM   8052  C C   . PHE C 1 152 ? -34.326 6.421   32.721  1.00 38.10  ? 152 PHE C C   1 
ATOM   8053  O O   . PHE C 1 152 ? -34.255 6.954   31.623  1.00 39.69  ? 152 PHE C O   1 
ATOM   8054  C CB  . PHE C 1 152 ? -34.915 7.676   34.821  1.00 53.93  ? 152 PHE C CB  1 
ATOM   8055  C CG  . PHE C 1 152 ? -34.529 9.054   34.356  1.00 61.16  ? 152 PHE C CG  1 
ATOM   8056  C CD1 . PHE C 1 152 ? -35.476 10.056  34.302  1.00 60.88  ? 152 PHE C CD1 1 
ATOM   8057  C CD2 . PHE C 1 152 ? -33.253 9.315   33.882  1.00 70.31  ? 152 PHE C CD2 1 
ATOM   8058  C CE1 . PHE C 1 152 ? -35.137 11.322  33.872  1.00 68.02  ? 152 PHE C CE1 1 
ATOM   8059  C CE2 . PHE C 1 152 ? -32.917 10.579  33.432  1.00 79.67  ? 152 PHE C CE2 1 
ATOM   8060  C CZ  . PHE C 1 152 ? -33.869 11.578  33.426  1.00 74.15  ? 152 PHE C CZ  1 
ATOM   8061  N N   . ALA C 1 153 ? -33.420 5.530   33.126  1.00 35.13  ? 153 ALA C N   1 
ATOM   8062  C CA  . ALA C 1 153 ? -32.298 5.161   32.281  1.00 35.14  ? 153 ALA C CA  1 
ATOM   8063  C C   . ALA C 1 153 ? -32.822 4.545   30.980  1.00 36.73  ? 153 ALA C C   1 
ATOM   8064  O O   . ALA C 1 153 ? -32.432 4.975   29.897  1.00 34.79  ? 153 ALA C O   1 
ATOM   8065  C CB  . ALA C 1 153 ? -31.368 4.237   33.033  1.00 35.96  ? 153 ALA C CB  1 
ATOM   8066  N N   . ALA C 1 154 ? -33.763 3.597   31.098  1.00 37.84  ? 154 ALA C N   1 
ATOM   8067  C CA  . ALA C 1 154 ? -34.416 2.963   29.952  1.00 42.90  ? 154 ALA C CA  1 
ATOM   8068  C C   . ALA C 1 154 ? -35.023 3.991   29.003  1.00 41.76  ? 154 ALA C C   1 
ATOM   8069  O O   . ALA C 1 154 ? -34.838 3.896   27.788  1.00 44.66  ? 154 ALA C O   1 
ATOM   8070  C CB  . ALA C 1 154 ? -35.488 2.000   30.424  1.00 44.00  ? 154 ALA C CB  1 
ATOM   8071  N N   . TYR C 1 155 ? -35.772 4.938   29.591  1.00 42.76  ? 155 TYR C N   1 
ATOM   8072  C CA  . TYR C 1 155 ? -36.438 6.031   28.877  1.00 44.23  ? 155 TYR C CA  1 
ATOM   8073  C C   . TYR C 1 155 ? -35.411 6.812   28.056  1.00 44.81  ? 155 TYR C C   1 
ATOM   8074  O O   . TYR C 1 155 ? -35.571 6.933   26.850  1.00 33.98  ? 155 TYR C O   1 
ATOM   8075  C CB  . TYR C 1 155 ? -37.203 6.868   29.910  1.00 41.35  ? 155 TYR C CB  1 
ATOM   8076  C CG  . TYR C 1 155 ? -37.689 8.251   29.555  1.00 44.81  ? 155 TYR C CG  1 
ATOM   8077  C CD1 . TYR C 1 155 ? -38.849 8.452   28.830  1.00 47.68  ? 155 TYR C CD1 1 
ATOM   8078  C CD2 . TYR C 1 155 ? -37.059 9.373   30.072  1.00 50.09  ? 155 TYR C CD2 1 
ATOM   8079  C CE1 . TYR C 1 155 ? -39.338 9.729   28.583  1.00 51.49  ? 155 TYR C CE1 1 
ATOM   8080  C CE2 . TYR C 1 155 ? -37.527 10.659  29.827  1.00 56.18  ? 155 TYR C CE2 1 
ATOM   8081  C CZ  . TYR C 1 155 ? -38.679 10.845  29.079  1.00 56.29  ? 155 TYR C CZ  1 
ATOM   8082  O OH  . TYR C 1 155 ? -39.152 12.135  28.857  1.00 52.29  ? 155 TYR C OH  1 
ATOM   8083  N N   . TYR C 1 156 ? -34.336 7.277   28.715  1.00 42.35  ? 156 TYR C N   1 
ATOM   8084  C CA  . TYR C 1 156 ? -33.309 8.042   28.042  1.00 45.20  ? 156 TYR C CA  1 
ATOM   8085  C C   . TYR C 1 156 ? -32.645 7.213   26.946  1.00 47.68  ? 156 TYR C C   1 
ATOM   8086  O O   . TYR C 1 156 ? -32.530 7.687   25.821  1.00 48.52  ? 156 TYR C O   1 
ATOM   8087  C CB  . TYR C 1 156 ? -32.262 8.587   29.024  1.00 46.48  ? 156 TYR C CB  1 
ATOM   8088  C CG  . TYR C 1 156 ? -31.342 9.566   28.338  1.00 47.70  ? 156 TYR C CG  1 
ATOM   8089  C CD1 . TYR C 1 156 ? -30.385 9.119   27.436  1.00 50.46  ? 156 TYR C CD1 1 
ATOM   8090  C CD2 . TYR C 1 156 ? -31.523 10.939  28.461  1.00 53.45  ? 156 TYR C CD2 1 
ATOM   8091  C CE1 . TYR C 1 156 ? -29.578 10.008  26.740  1.00 56.73  ? 156 TYR C CE1 1 
ATOM   8092  C CE2 . TYR C 1 156 ? -30.718 11.845  27.780  1.00 53.40  ? 156 TYR C CE2 1 
ATOM   8093  C CZ  . TYR C 1 156 ? -29.748 11.375  26.911  1.00 55.05  ? 156 TYR C CZ  1 
ATOM   8094  O OH  . TYR C 1 156 ? -28.942 12.239  26.212  1.00 56.71  ? 156 TYR C OH  1 
ATOM   8095  N N   . ASN C 1 157 ? -32.215 5.987   27.281  1.00 53.46  ? 157 ASN C N   1 
ATOM   8096  C CA  . ASN C 1 157 ? -31.415 5.160   26.382  1.00 52.28  ? 157 ASN C CA  1 
ATOM   8097  C C   . ASN C 1 157 ? -32.222 4.733   25.160  1.00 54.36  ? 157 ASN C C   1 
ATOM   8098  O O   . ASN C 1 157 ? -31.639 4.472   24.108  1.00 66.51  ? 157 ASN C O   1 
ATOM   8099  C CB  . ASN C 1 157 ? -30.886 3.875   27.034  1.00 50.67  ? 157 ASN C CB  1 
ATOM   8100  C CG  . ASN C 1 157 ? -29.885 4.107   28.145  1.00 51.40  ? 157 ASN C CG  1 
ATOM   8101  O OD1 . ASN C 1 157 ? -29.206 5.131   28.184  1.00 56.04  ? 157 ASN C OD1 1 
ATOM   8102  N ND2 . ASN C 1 157 ? -29.791 3.153   29.057  1.00 50.16  ? 157 ASN C ND2 1 
ATOM   8103  N N   . ALA C 1 158 ? -33.546 4.630   25.321  1.00 55.20  ? 158 ALA C N   1 
ATOM   8104  C CA  . ALA C 1 158 ? -34.467 4.361   24.221  1.00 55.38  ? 158 ALA C CA  1 
ATOM   8105  C C   . ALA C 1 158 ? -34.787 5.603   23.373  1.00 54.72  ? 158 ALA C C   1 
ATOM   8106  O O   . ALA C 1 158 ? -35.676 5.541   22.523  1.00 54.08  ? 158 ALA C O   1 
ATOM   8107  C CB  . ALA C 1 158 ? -35.738 3.791   24.799  1.00 55.05  ? 158 ALA C CB  1 
ATOM   8108  N N   . GLY C 1 159 ? -34.119 6.745   23.620  1.00 51.96  ? 159 GLY C N   1 
ATOM   8109  C CA  . GLY C 1 159 ? -34.268 7.935   22.787  1.00 54.17  ? 159 GLY C CA  1 
ATOM   8110  C C   . GLY C 1 159 ? -35.597 8.682   22.938  1.00 53.29  ? 159 GLY C C   1 
ATOM   8111  O O   . GLY C 1 159 ? -35.927 9.486   22.084  1.00 50.26  ? 159 GLY C O   1 
ATOM   8112  N N   . LYS C 1 160 ? -36.312 8.488   24.054  1.00 59.76  ? 160 LYS C N   1 
ATOM   8113  C CA  . LYS C 1 160 ? -37.625 9.078   24.296  1.00 57.07  ? 160 LYS C CA  1 
ATOM   8114  C C   . LYS C 1 160 ? -37.539 10.279  25.241  1.00 62.33  ? 160 LYS C C   1 
ATOM   8115  O O   . LYS C 1 160 ? -38.580 10.764  25.690  1.00 58.20  ? 160 LYS C O   1 
ATOM   8116  C CB  . LYS C 1 160 ? -38.562 8.082   24.985  1.00 61.41  ? 160 LYS C CB  1 
ATOM   8117  C CG  . LYS C 1 160 ? -38.517 6.677   24.422  1.00 70.42  ? 160 LYS C CG  1 
ATOM   8118  C CD  . LYS C 1 160 ? -39.391 5.652   25.096  1.00 76.52  ? 160 LYS C CD  1 
ATOM   8119  C CE  . LYS C 1 160 ? -39.254 4.316   24.388  1.00 86.20  ? 160 LYS C CE  1 
ATOM   8120  N NZ  . LYS C 1 160 ? -40.389 3.399   24.649  1.00 86.14  ? 160 LYS C NZ  1 
ATOM   8121  N N   . PHE C 1 161 ? -36.317 10.751  25.558  1.00 58.98  ? 161 PHE C N   1 
ATOM   8122  C CA  . PHE C 1 161 ? -36.167 11.889  26.447  1.00 55.13  ? 161 PHE C CA  1 
ATOM   8123  C C   . PHE C 1 161 ? -36.911 13.105  25.890  1.00 52.12  ? 161 PHE C C   1 
ATOM   8124  O O   . PHE C 1 161 ? -36.792 13.423  24.718  1.00 48.45  ? 161 PHE C O   1 
ATOM   8125  C CB  . PHE C 1 161 ? -34.703 12.295  26.657  1.00 57.53  ? 161 PHE C CB  1 
ATOM   8126  C CG  . PHE C 1 161 ? -34.578 13.414  27.669  1.00 61.01  ? 161 PHE C CG  1 
ATOM   8127  C CD1 . PHE C 1 161 ? -34.785 13.167  29.025  1.00 59.52  ? 161 PHE C CD1 1 
ATOM   8128  C CD2 . PHE C 1 161 ? -34.397 14.728  27.266  1.00 56.42  ? 161 PHE C CD2 1 
ATOM   8129  C CE1 . PHE C 1 161 ? -34.738 14.192  29.956  1.00 54.23  ? 161 PHE C CE1 1 
ATOM   8130  C CE2 . PHE C 1 161 ? -34.348 15.751  28.204  1.00 61.75  ? 161 PHE C CE2 1 
ATOM   8131  C CZ  . PHE C 1 161 ? -34.501 15.480  29.546  1.00 57.02  ? 161 PHE C CZ  1 
ATOM   8132  N N   . ASN C 1 162 ? -37.616 13.821  26.768  1.00 52.37  ? 162 ASN C N   1 
ATOM   8133  C CA  . ASN C 1 162 ? -38.468 14.932  26.390  1.00 49.39  ? 162 ASN C CA  1 
ATOM   8134  C C   . ASN C 1 162 ? -38.481 15.864  27.586  1.00 49.75  ? 162 ASN C C   1 
ATOM   8135  O O   . ASN C 1 162 ? -38.848 15.424  28.670  1.00 52.73  ? 162 ASN C O   1 
ATOM   8136  C CB  . ASN C 1 162 ? -39.856 14.396  26.044  1.00 57.11  ? 162 ASN C CB  1 
ATOM   8137  C CG  . ASN C 1 162 ? -40.891 15.459  25.768  1.00 56.86  ? 162 ASN C CG  1 
ATOM   8138  O OD1 . ASN C 1 162 ? -41.324 16.187  26.660  1.00 69.39  ? 162 ASN C OD1 1 
ATOM   8139  N ND2 . ASN C 1 162 ? -41.342 15.508  24.534  1.00 69.03  ? 162 ASN C ND2 1 
ATOM   8140  N N   . LYS C 1 163 ? -38.082 17.124  27.405  1.00 55.15  ? 163 LYS C N   1 
ATOM   8141  C CA  . LYS C 1 163 ? -37.983 18.053  28.526  1.00 62.14  ? 163 LYS C CA  1 
ATOM   8142  C C   . LYS C 1 163 ? -39.215 17.956  29.448  1.00 55.55  ? 163 LYS C C   1 
ATOM   8143  O O   . LYS C 1 163 ? -39.069 18.099  30.656  1.00 53.58  ? 163 LYS C O   1 
ATOM   8144  C CB  . LYS C 1 163 ? -37.747 19.494  28.029  1.00 71.29  ? 163 LYS C CB  1 
ATOM   8145  C CG  . LYS C 1 163 ? -37.044 20.461  28.989  1.00 87.44  ? 163 LYS C CG  1 
ATOM   8146  C CD  . LYS C 1 163 ? -37.915 21.576  29.635  1.00 105.52 ? 163 LYS C CD  1 
ATOM   8147  C CE  . LYS C 1 163 ? -38.742 21.131  30.836  1.00 106.65 ? 163 LYS C CE  1 
ATOM   8148  N NZ  . LYS C 1 163 ? -39.475 22.237  31.508  1.00 97.59  ? 163 LYS C NZ  1 
ATOM   8149  N N   . ASN C 1 164 ? -40.419 17.681  28.925  1.00 49.37  ? 164 ASN C N   1 
ATOM   8150  C CA  . ASN C 1 164 ? -41.643 17.912  29.689  1.00 54.70  ? 164 ASN C CA  1 
ATOM   8151  C C   . ASN C 1 164 ? -42.047 16.728  30.564  1.00 55.29  ? 164 ASN C C   1 
ATOM   8152  O O   . ASN C 1 164 ? -42.609 16.943  31.634  1.00 39.75  ? 164 ASN C O   1 
ATOM   8153  C CB  . ASN C 1 164 ? -42.822 18.276  28.785  1.00 58.51  ? 164 ASN C CB  1 
ATOM   8154  C CG  . ASN C 1 164 ? -42.551 19.570  28.060  1.00 57.59  ? 164 ASN C CG  1 
ATOM   8155  O OD1 . ASN C 1 164 ? -42.287 20.583  28.695  1.00 55.11  ? 164 ASN C OD1 1 
ATOM   8156  N ND2 . ASN C 1 164 ? -42.528 19.526  26.741  1.00 64.06  ? 164 ASN C ND2 1 
ATOM   8157  N N   . THR C 1 165 ? -41.775 15.502  30.096  1.00 62.51  ? 165 THR C N   1 
ATOM   8158  C CA  . THR C 1 165 ? -42.295 14.283  30.700  1.00 60.50  ? 165 THR C CA  1 
ATOM   8159  C C   . THR C 1 165 ? -41.194 13.494  31.418  1.00 57.07  ? 165 THR C C   1 
ATOM   8160  O O   . THR C 1 165 ? -41.437 12.386  31.905  1.00 51.08  ? 165 THR C O   1 
ATOM   8161  C CB  . THR C 1 165 ? -42.960 13.425  29.612  1.00 65.49  ? 165 THR C CB  1 
ATOM   8162  O OG1 . THR C 1 165 ? -41.947 13.004  28.679  1.00 64.66  ? 165 THR C OG1 1 
ATOM   8163  C CG2 . THR C 1 165 ? -44.081 14.171  28.914  1.00 59.98  ? 165 THR C CG2 1 
ATOM   8164  N N   . ALA C 1 166 ? -39.986 14.076  31.497  1.00 50.42  ? 166 ALA C N   1 
ATOM   8165  C CA  . ALA C 1 166 ? -38.836 13.448  32.141  1.00 44.65  ? 166 ALA C CA  1 
ATOM   8166  C C   . ALA C 1 166 ? -39.135 13.091  33.601  1.00 35.74  ? 166 ALA C C   1 
ATOM   8167  O O   . ALA C 1 166 ? -38.608 12.099  34.112  1.00 36.59  ? 166 ALA C O   1 
ATOM   8168  C CB  . ALA C 1 166 ? -37.626 14.355  32.023  1.00 42.72  ? 166 ALA C CB  1 
ATOM   8169  N N   . TRP C 1 167 ? -39.991 13.871  34.269  1.00 31.46  ? 167 TRP C N   1 
ATOM   8170  C CA  . TRP C 1 167 ? -40.208 13.658  35.692  1.00 34.01  ? 167 TRP C CA  1 
ATOM   8171  C C   . TRP C 1 167 ? -40.994 12.380  35.890  1.00 33.05  ? 167 TRP C C   1 
ATOM   8172  O O   . TRP C 1 167 ? -40.984 11.814  36.980  1.00 33.62  ? 167 TRP C O   1 
ATOM   8173  C CB  . TRP C 1 167 ? -40.910 14.840  36.379  1.00 36.38  ? 167 TRP C CB  1 
ATOM   8174  C CG  . TRP C 1 167 ? -42.300 15.042  35.865  1.00 38.73  ? 167 TRP C CG  1 
ATOM   8175  C CD1 . TRP C 1 167 ? -42.640 15.788  34.784  1.00 37.47  ? 167 TRP C CD1 1 
ATOM   8176  C CD2 . TRP C 1 167 ? -43.520 14.433  36.335  1.00 39.63  ? 167 TRP C CD2 1 
ATOM   8177  N NE1 . TRP C 1 167 ? -43.982 15.696  34.553  1.00 38.47  ? 167 TRP C NE1 1 
ATOM   8178  C CE2 . TRP C 1 167 ? -44.558 14.886  35.486  1.00 41.16  ? 167 TRP C CE2 1 
ATOM   8179  C CE3 . TRP C 1 167 ? -43.860 13.583  37.396  1.00 38.55  ? 167 TRP C CE3 1 
ATOM   8180  C CZ2 . TRP C 1 167 ? -45.900 14.527  35.657  1.00 39.76  ? 167 TRP C CZ2 1 
ATOM   8181  C CZ3 . TRP C 1 167 ? -45.189 13.225  37.562  1.00 42.55  ? 167 TRP C CZ3 1 
ATOM   8182  C CH2 . TRP C 1 167 ? -46.198 13.689  36.705  1.00 38.73  ? 167 TRP C CH2 1 
ATOM   8183  N N   . GLU C 1 168 ? -41.682 11.932  34.844  1.00 36.10  ? 168 GLU C N   1 
ATOM   8184  C CA  . GLU C 1 168 ? -42.600 10.812  34.996  1.00 36.63  ? 168 GLU C CA  1 
ATOM   8185  C C   . GLU C 1 168 ? -41.848 9.521   35.333  1.00 32.02  ? 168 GLU C C   1 
ATOM   8186  O O   . GLU C 1 168 ? -42.104 8.949   36.387  1.00 29.80  ? 168 GLU C O   1 
ATOM   8187  C CB  . GLU C 1 168 ? -43.481 10.747  33.757  1.00 42.22  ? 168 GLU C CB  1 
ATOM   8188  C CG  . GLU C 1 168 ? -44.362 11.972  33.657  1.00 56.93  ? 168 GLU C CG  1 
ATOM   8189  C CD  . GLU C 1 168 ? -45.475 11.849  32.635  1.00 62.94  ? 168 GLU C CD  1 
ATOM   8190  O OE1 . GLU C 1 168 ? -45.600 12.767  31.800  1.00 72.64  ? 168 GLU C OE1 1 
ATOM   8191  O OE2 . GLU C 1 168 ? -46.175 10.806  32.654  1.00 69.70  ? 168 GLU C OE2 1 
ATOM   8192  N N   . PRO C 1 169 ? -40.923 8.995   34.485  1.00 32.35  ? 169 PRO C N   1 
ATOM   8193  C CA  . PRO C 1 169 ? -40.093 7.846   34.855  1.00 29.48  ? 169 PRO C CA  1 
ATOM   8194  C C   . PRO C 1 169 ? -39.280 8.070   36.119  1.00 29.73  ? 169 PRO C C   1 
ATOM   8195  O O   . PRO C 1 169 ? -39.117 7.159   36.906  1.00 30.34  ? 169 PRO C O   1 
ATOM   8196  C CB  . PRO C 1 169 ? -39.126 7.681   33.671  1.00 29.85  ? 169 PRO C CB  1 
ATOM   8197  C CG  . PRO C 1 169 ? -39.203 8.995   32.916  1.00 31.25  ? 169 PRO C CG  1 
ATOM   8198  C CD  . PRO C 1 169 ? -40.620 9.462   33.118  1.00 34.70  ? 169 PRO C CD  1 
ATOM   8199  N N   . MET C 1 170 ? -38.790 9.299   36.311  1.00 33.22  ? 170 MET C N   1 
ATOM   8200  C CA  . MET C 1 170 ? -38.017 9.636   37.485  1.00 36.04  ? 170 MET C CA  1 
ATOM   8201  C C   . MET C 1 170 ? -38.896 9.444   38.729  1.00 37.22  ? 170 MET C C   1 
ATOM   8202  O O   . MET C 1 170 ? -38.419 8.907   39.725  1.00 43.71  ? 170 MET C O   1 
ATOM   8203  C CB  . MET C 1 170 ? -37.465 11.062  37.342  1.00 41.90  ? 170 MET C CB  1 
ATOM   8204  C CG  . MET C 1 170 ? -36.750 11.612  38.587  1.00 48.68  ? 170 MET C CG  1 
ATOM   8205  S SD  . MET C 1 170 ? -35.253 10.729  39.131  1.00 48.73  ? 170 MET C SD  1 
ATOM   8206  C CE  . MET C 1 170 ? -34.064 11.290  37.913  1.00 52.74  ? 170 MET C CE  1 
ATOM   8207  N N   . PHE C 1 171 ? -40.189 9.798   38.652  1.00 32.89  ? 171 PHE C N   1 
ATOM   8208  C CA  . PHE C 1 171 ? -41.149 9.533   39.721  1.00 33.88  ? 171 PHE C CA  1 
ATOM   8209  C C   . PHE C 1 171 ? -41.378 8.041   39.974  1.00 33.89  ? 171 PHE C C   1 
ATOM   8210  O O   . PHE C 1 171 ? -41.644 7.644   41.109  1.00 36.68  ? 171 PHE C O   1 
ATOM   8211  C CB  . PHE C 1 171 ? -42.492 10.195  39.411  1.00 33.61  ? 171 PHE C CB  1 
ATOM   8212  C CG  . PHE C 1 171 ? -43.643 9.750   40.276  1.00 31.99  ? 171 PHE C CG  1 
ATOM   8213  C CD1 . PHE C 1 171 ? -43.885 10.323  41.505  1.00 32.37  ? 171 PHE C CD1 1 
ATOM   8214  C CD2 . PHE C 1 171 ? -44.518 8.764   39.844  1.00 36.83  ? 171 PHE C CD2 1 
ATOM   8215  C CE1 . PHE C 1 171 ? -44.974 9.932   42.275  1.00 30.93  ? 171 PHE C CE1 1 
ATOM   8216  C CE2 . PHE C 1 171 ? -45.605 8.365   40.622  1.00 32.65  ? 171 PHE C CE2 1 
ATOM   8217  C CZ  . PHE C 1 171 ? -45.832 8.955   41.841  1.00 29.73  ? 171 PHE C CZ  1 
ATOM   8218  N N   . GLU C 1 172 ? -41.338 7.212   38.931  1.00 32.99  ? 172 GLU C N   1 
ATOM   8219  C CA  . GLU C 1 172 ? -41.556 5.783   39.106  1.00 36.16  ? 172 GLU C CA  1 
ATOM   8220  C C   . GLU C 1 172 ? -40.347 5.168   39.805  1.00 34.36  ? 172 GLU C C   1 
ATOM   8221  O O   . GLU C 1 172 ? -40.496 4.363   40.706  1.00 35.80  ? 172 GLU C O   1 
ATOM   8222  C CB  . GLU C 1 172 ? -41.793 5.085   37.761  1.00 44.66  ? 172 GLU C CB  1 
ATOM   8223  C CG  . GLU C 1 172 ? -43.114 5.456   37.091  1.00 48.84  ? 172 GLU C CG  1 
ATOM   8224  C CD  . GLU C 1 172 ? -44.371 5.135   37.895  1.00 50.03  ? 172 GLU C CD  1 
ATOM   8225  O OE1 . GLU C 1 172 ? -44.400 4.056   38.559  1.00 46.01  ? 172 GLU C OE1 1 
ATOM   8226  O OE2 . GLU C 1 172 ? -45.347 5.930   37.811  1.00 48.53  ? 172 GLU C OE2 1 
ATOM   8227  N N   . ASP C 1 173 ? -39.143 5.549   39.376  1.00 33.66  ? 173 ASP C N   1 
ATOM   8228  C CA  . ASP C 1 173 ? -37.912 5.145   40.027  1.00 31.36  ? 173 ASP C CA  1 
ATOM   8229  C C   . ASP C 1 173 ? -37.939 5.573   41.497  1.00 39.14  ? 173 ASP C C   1 
ATOM   8230  O O   . ASP C 1 173 ? -37.519 4.807   42.367  1.00 39.44  ? 173 ASP C O   1 
ATOM   8231  C CB  . ASP C 1 173 ? -36.720 5.726   39.279  1.00 30.63  ? 173 ASP C CB  1 
ATOM   8232  C CG  . ASP C 1 173 ? -36.388 4.946   38.017  1.00 31.79  ? 173 ASP C CG  1 
ATOM   8233  O OD1 . ASP C 1 173 ? -36.970 3.859   37.843  1.00 35.86  ? 173 ASP C OD1 1 
ATOM   8234  O OD2 . ASP C 1 173 ? -35.508 5.397   37.230  1.00 32.58  ? 173 ASP C OD2 1 
ATOM   8235  N N   . ALA C 1 174 ? -38.472 6.776   41.784  1.00 41.79  ? 174 ALA C N   1 
ATOM   8236  C CA  . ALA C 1 174 ? -38.583 7.278   43.150  1.00 38.71  ? 174 ALA C CA  1 
ATOM   8237  C C   . ALA C 1 174 ? -39.544 6.419   43.965  1.00 38.30  ? 174 ALA C C   1 
ATOM   8238  O O   . ALA C 1 174 ? -39.228 6.048   45.091  1.00 39.39  ? 174 ALA C O   1 
ATOM   8239  C CB  . ALA C 1 174 ? -39.010 8.717   43.165  1.00 40.26  ? 174 ALA C CB  1 
ATOM   8240  N N   . MET C 1 175 ? -40.686 6.036   43.385  1.00 41.53  ? 175 MET C N   1 
ATOM   8241  C CA  . MET C 1 175 ? -41.645 5.201   44.104  1.00 43.31  ? 175 MET C CA  1 
ATOM   8242  C C   . MET C 1 175 ? -41.043 3.831   44.431  1.00 42.47  ? 175 MET C C   1 
ATOM   8243  O O   . MET C 1 175 ? -41.198 3.302   45.539  1.00 41.19  ? 175 MET C O   1 
ATOM   8244  C CB  . MET C 1 175 ? -42.915 5.034   43.265  1.00 44.51  ? 175 MET C CB  1 
ATOM   8245  C CG  . MET C 1 175 ? -43.725 6.328   43.224  1.00 46.09  ? 175 MET C CG  1 
ATOM   8246  S SD  . MET C 1 175 ? -44.531 6.782   44.804  1.00 53.35  ? 175 MET C SD  1 
ATOM   8247  C CE  . MET C 1 175 ? -45.666 5.401   45.055  1.00 46.82  ? 175 MET C CE  1 
ATOM   8248  N N   . ASP C 1 176 ? -40.330 3.281   43.442  1.00 41.43  ? 176 ASP C N   1 
ATOM   8249  C CA  . ASP C 1 176 ? -39.715 1.972   43.526  1.00 38.18  ? 176 ASP C CA  1 
ATOM   8250  C C   . ASP C 1 176 ? -38.591 1.977   44.548  1.00 38.39  ? 176 ASP C C   1 
ATOM   8251  O O   . ASP C 1 176 ? -38.498 1.082   45.370  1.00 48.65  ? 176 ASP C O   1 
ATOM   8252  C CB  . ASP C 1 176 ? -39.106 1.522   42.197  1.00 39.28  ? 176 ASP C CB  1 
ATOM   8253  C CG  . ASP C 1 176 ? -40.094 1.048   41.145  1.00 39.72  ? 176 ASP C CG  1 
ATOM   8254  O OD1 . ASP C 1 176 ? -41.128 0.402   41.532  1.00 31.10  ? 176 ASP C OD1 1 
ATOM   8255  O OD2 . ASP C 1 176 ? -39.772 1.267   39.934  1.00 44.67  ? 176 ASP C OD2 1 
ATOM   8256  N N   . LEU C 1 177 ? -37.693 2.954   44.469  1.00 40.38  ? 177 LEU C N   1 
ATOM   8257  C CA  . LEU C 1 177 ? -36.554 2.945   45.366  1.00 34.70  ? 177 LEU C CA  1 
ATOM   8258  C C   . LEU C 1 177 ? -37.031 3.252   46.786  1.00 33.03  ? 177 LEU C C   1 
ATOM   8259  O O   . LEU C 1 177 ? -36.606 2.609   47.742  1.00 34.49  ? 177 LEU C O   1 
ATOM   8260  C CB  . LEU C 1 177 ? -35.507 3.919   44.834  1.00 37.98  ? 177 LEU C CB  1 
ATOM   8261  C CG  . LEU C 1 177 ? -34.229 4.032   45.661  1.00 41.71  ? 177 LEU C CG  1 
ATOM   8262  C CD1 . LEU C 1 177 ? -33.671 2.651   45.970  1.00 41.14  ? 177 LEU C CD1 1 
ATOM   8263  C CD2 . LEU C 1 177 ? -33.207 4.887   44.925  1.00 39.18  ? 177 LEU C CD2 1 
ATOM   8264  N N   . MET C 1 178 ? -37.984 4.163   46.936  1.00 33.46  ? 178 MET C N   1 
ATOM   8265  C CA  . MET C 1 178 ? -38.443 4.502   48.268  1.00 36.52  ? 178 MET C CA  1 
ATOM   8266  C C   . MET C 1 178 ? -39.100 3.289   48.935  1.00 39.00  ? 178 MET C C   1 
ATOM   8267  O O   . MET C 1 178 ? -38.915 3.065   50.147  1.00 38.29  ? 178 MET C O   1 
ATOM   8268  C CB  . MET C 1 178 ? -39.398 5.703   48.248  1.00 41.33  ? 178 MET C CB  1 
ATOM   8269  C CG  . MET C 1 178 ? -39.656 6.296   49.643  1.00 44.52  ? 178 MET C CG  1 
ATOM   8270  S SD  . MET C 1 178 ? -38.172 6.971   50.490  1.00 52.13  ? 178 MET C SD  1 
ATOM   8271  C CE  . MET C 1 178 ? -38.071 5.916   51.947  1.00 49.40  ? 178 MET C CE  1 
ATOM   8272  N N   . ALA C 1 179 ? -39.848 2.492   48.152  1.00 39.15  ? 179 ALA C N   1 
ATOM   8273  C CA  . ALA C 1 179 ? -40.582 1.353   48.698  1.00 35.28  ? 179 ALA C CA  1 
ATOM   8274  C C   . ALA C 1 179 ? -39.657 0.231   49.167  1.00 34.68  ? 179 ALA C C   1 
ATOM   8275  O O   . ALA C 1 179 ? -40.058 -0.529  50.054  1.00 32.04  ? 179 ALA C O   1 
ATOM   8276  C CB  . ALA C 1 179 ? -41.574 0.852   47.694  1.00 34.49  ? 179 ALA C CB  1 
ATOM   8277  N N   . LYS C 1 180 ? -38.436 0.145   48.595  1.00 31.27  ? 180 LYS C N   1 
ATOM   8278  C CA  . LYS C 1 180 ? -37.492 -0.934  48.880  1.00 32.21  ? 180 LYS C CA  1 
ATOM   8279  C C   . LYS C 1 180 ? -36.432 -0.582  49.931  1.00 32.66  ? 180 LYS C C   1 
ATOM   8280  O O   . LYS C 1 180 ? -35.859 -1.497  50.501  1.00 30.78  ? 180 LYS C O   1 
ATOM   8281  C CB  . LYS C 1 180 ? -36.683 -1.296  47.638  1.00 31.45  ? 180 LYS C CB  1 
ATOM   8282  C CG  . LYS C 1 180 ? -37.505 -1.861  46.498  1.00 38.36  ? 180 LYS C CG  1 
ATOM   8283  C CD  . LYS C 1 180 ? -36.718 -2.130  45.242  1.00 40.19  ? 180 LYS C CD  1 
ATOM   8284  C CE  . LYS C 1 180 ? -37.567 -2.031  43.991  1.00 43.28  ? 180 LYS C CE  1 
ATOM   8285  N NZ  . LYS C 1 180 ? -38.774 -2.879  44.106  1.00 47.09  ? 180 LYS C NZ  1 
ATOM   8286  N N   . LEU C 1 181 ? -36.112 0.702   50.162  1.00 28.50  ? 181 LEU C N   1 
ATOM   8287  C CA  . LEU C 1 181 ? -34.996 1.047   51.034  1.00 32.96  ? 181 LEU C CA  1 
ATOM   8288  C C   . LEU C 1 181 ? -35.141 0.479   52.445  1.00 33.30  ? 181 LEU C C   1 
ATOM   8289  O O   . LEU C 1 181 ? -34.141 0.171   53.093  1.00 36.21  ? 181 LEU C O   1 
ATOM   8290  C CB  . LEU C 1 181 ? -34.863 2.567   51.126  1.00 37.84  ? 181 LEU C CB  1 
ATOM   8291  C CG  . LEU C 1 181 ? -34.279 3.244   49.885  1.00 40.22  ? 181 LEU C CG  1 
ATOM   8292  C CD1 . LEU C 1 181 ? -34.215 4.758   50.050  1.00 36.81  ? 181 LEU C CD1 1 
ATOM   8293  C CD2 . LEU C 1 181 ? -32.907 2.671   49.566  1.00 44.08  ? 181 LEU C CD2 1 
ATOM   8294  N N   . PRO C 1 182 ? -36.348 0.427   53.045  1.00 31.96  ? 182 PRO C N   1 
ATOM   8295  C CA  . PRO C 1 182 ? -36.488 -0.164  54.379  1.00 29.99  ? 182 PRO C CA  1 
ATOM   8296  C C   . PRO C 1 182 ? -36.220 -1.663  54.408  1.00 30.35  ? 182 PRO C C   1 
ATOM   8297  O O   . PRO C 1 182 ? -35.526 -2.123  55.305  1.00 33.94  ? 182 PRO C O   1 
ATOM   8298  C CB  . PRO C 1 182 ? -37.922 0.194   54.774  1.00 30.49  ? 182 PRO C CB  1 
ATOM   8299  C CG  . PRO C 1 182 ? -38.265 1.356   53.878  1.00 30.02  ? 182 PRO C CG  1 
ATOM   8300  C CD  . PRO C 1 182 ? -37.588 1.055   52.564  1.00 30.47  ? 182 PRO C CD  1 
ATOM   8301  N N   . SER C 1 183 ? -36.720 -2.396  53.415  1.00 28.93  ? 183 SER C N   1 
ATOM   8302  C CA  . SER C 1 183 ? -36.313 -3.779  53.192  1.00 35.61  ? 183 SER C CA  1 
ATOM   8303  C C   . SER C 1 183 ? -34.796 -3.912  53.086  1.00 34.73  ? 183 SER C C   1 
ATOM   8304  O O   . SER C 1 183 ? -34.220 -4.819  53.691  1.00 41.79  ? 183 SER C O   1 
ATOM   8305  C CB  . SER C 1 183 ? -36.932 -4.405  51.952  1.00 37.39  ? 183 SER C CB  1 
ATOM   8306  O OG  . SER C 1 183 ? -38.335 -4.471  52.063  1.00 47.52  ? 183 SER C OG  1 
ATOM   8307  N N   . LEU C 1 184 ? -34.155 -3.048  52.293  1.00 32.08  ? 184 LEU C N   1 
ATOM   8308  C CA  . LEU C 1 184 ? -32.717 -3.138  52.095  1.00 29.81  ? 184 LEU C CA  1 
ATOM   8309  C C   . LEU C 1 184 ? -32.017 -2.932  53.424  1.00 27.31  ? 184 LEU C C   1 
ATOM   8310  O O   . LEU C 1 184 ? -31.171 -3.740  53.814  1.00 27.52  ? 184 LEU C O   1 
ATOM   8311  C CB  . LEU C 1 184 ? -32.243 -2.111  51.073  1.00 31.97  ? 184 LEU C CB  1 
ATOM   8312  C CG  . LEU C 1 184 ? -30.737 -2.079  50.854  1.00 32.61  ? 184 LEU C CG  1 
ATOM   8313  C CD1 . LEU C 1 184 ? -30.209 -3.486  50.659  1.00 32.03  ? 184 LEU C CD1 1 
ATOM   8314  C CD2 . LEU C 1 184 ? -30.368 -1.225  49.643  1.00 31.25  ? 184 LEU C CD2 1 
ATOM   8315  N N   . GLY C 1 185 ? -32.408 -1.880  54.137  1.00 28.58  ? 185 GLY C N   1 
ATOM   8316  C CA  . GLY C 1 185 ? -31.820 -1.596  55.444  1.00 31.27  ? 185 GLY C CA  1 
ATOM   8317  C C   . GLY C 1 185 ? -31.953 -2.772  56.407  1.00 29.86  ? 185 GLY C C   1 
ATOM   8318  O O   . GLY C 1 185 ? -30.996 -3.162  57.076  1.00 33.10  ? 185 GLY C O   1 
ATOM   8319  N N   . ALA C 1 186 ? -33.164 -3.327  56.480  1.00 33.41  ? 186 ALA C N   1 
ATOM   8320  C CA  . ALA C 1 186 ? -33.451 -4.442  57.380  1.00 33.98  ? 186 ALA C CA  1 
ATOM   8321  C C   . ALA C 1 186 ? -32.637 -5.672  56.979  1.00 31.91  ? 186 ALA C C   1 
ATOM   8322  O O   . ALA C 1 186 ? -32.100 -6.338  57.853  1.00 29.84  ? 186 ALA C O   1 
ATOM   8323  C CB  . ALA C 1 186 ? -34.918 -4.768  57.403  1.00 33.05  ? 186 ALA C CB  1 
ATOM   8324  N N   . TYR C 1 187 ? -32.503 -5.957  55.673  1.00 32.03  ? 187 TYR C N   1 
ATOM   8325  C CA  . TYR C 1 187 ? -31.703 -7.102  55.247  1.00 29.89  ? 187 TYR C CA  1 
ATOM   8326  C C   . TYR C 1 187 ? -30.284 -7.020  55.801  1.00 29.56  ? 187 TYR C C   1 
ATOM   8327  O O   . TYR C 1 187 ? -29.736 -8.023  56.303  1.00 30.72  ? 187 TYR C O   1 
ATOM   8328  C CB  . TYR C 1 187 ? -31.559 -7.211  53.737  1.00 31.04  ? 187 TYR C CB  1 
ATOM   8329  C CG  . TYR C 1 187 ? -31.086 -8.573  53.302  1.00 37.61  ? 187 TYR C CG  1 
ATOM   8330  C CD1 . TYR C 1 187 ? -31.998 -9.609  53.101  1.00 41.98  ? 187 TYR C CD1 1 
ATOM   8331  C CD2 . TYR C 1 187 ? -29.737 -8.858  53.142  1.00 42.58  ? 187 TYR C CD2 1 
ATOM   8332  C CE1 . TYR C 1 187 ? -31.589 -10.878 52.717  1.00 42.39  ? 187 TYR C CE1 1 
ATOM   8333  C CE2 . TYR C 1 187 ? -29.307 -10.126 52.761  1.00 47.05  ? 187 TYR C CE2 1 
ATOM   8334  C CZ  . TYR C 1 187 ? -30.233 -11.147 52.557  1.00 48.17  ? 187 TYR C CZ  1 
ATOM   8335  O OH  . TYR C 1 187 ? -29.803 -12.428 52.193  1.00 47.43  ? 187 TYR C OH  1 
ATOM   8336  N N   . ILE C 1 188 ? -29.687 -5.820  55.672  1.00 27.19  ? 188 ILE C N   1 
ATOM   8337  C CA  . ILE C 1 188 ? -28.331 -5.567  56.140  1.00 26.13  ? 188 ILE C CA  1 
ATOM   8338  C C   . ILE C 1 188 ? -28.257 -5.743  57.658  1.00 27.75  ? 188 ILE C C   1 
ATOM   8339  O O   . ILE C 1 188 ? -27.351 -6.440  58.156  1.00 25.47  ? 188 ILE C O   1 
ATOM   8340  C CB  . ILE C 1 188 ? -27.860 -4.195  55.638  1.00 25.79  ? 188 ILE C CB  1 
ATOM   8341  C CG1 . ILE C 1 188 ? -27.715 -4.211  54.115  1.00 25.86  ? 188 ILE C CG1 1 
ATOM   8342  C CG2 . ILE C 1 188 ? -26.568 -3.771  56.293  1.00 26.19  ? 188 ILE C CG2 1 
ATOM   8343  C CD1 . ILE C 1 188 ? -27.586 -2.806  53.516  1.00 26.83  ? 188 ILE C CD1 1 
ATOM   8344  N N   . TYR C 1 189 ? -29.238 -5.172  58.389  1.00 26.15  ? 189 TYR C N   1 
ATOM   8345  C CA  . TYR C 1 189 ? -29.247 -5.337  59.831  1.00 24.34  ? 189 TYR C CA  1 
ATOM   8346  C C   . TYR C 1 189 ? -29.177 -6.800  60.217  1.00 25.95  ? 189 TYR C C   1 
ATOM   8347  O O   . TYR C 1 189 ? -28.410 -7.171  61.100  1.00 33.63  ? 189 TYR C O   1 
ATOM   8348  C CB  . TYR C 1 189 ? -30.536 -4.846  60.468  1.00 28.33  ? 189 TYR C CB  1 
ATOM   8349  C CG  . TYR C 1 189 ? -30.494 -4.771  61.983  1.00 26.11  ? 189 TYR C CG  1 
ATOM   8350  C CD1 . TYR C 1 189 ? -29.577 -3.966  62.613  1.00 26.30  ? 189 TYR C CD1 1 
ATOM   8351  C CD2 . TYR C 1 189 ? -31.427 -5.423  62.775  1.00 26.53  ? 189 TYR C CD2 1 
ATOM   8352  C CE1 . TYR C 1 189 ? -29.525 -3.890  63.992  1.00 26.59  ? 189 TYR C CE1 1 
ATOM   8353  C CE2 . TYR C 1 189 ? -31.420 -5.324  64.154  1.00 26.45  ? 189 TYR C CE2 1 
ATOM   8354  C CZ  . TYR C 1 189 ? -30.456 -4.554  64.771  1.00 27.55  ? 189 TYR C CZ  1 
ATOM   8355  O OH  . TYR C 1 189 ? -30.388 -4.421  66.154  1.00 30.15  ? 189 TYR C OH  1 
ATOM   8356  N N   . ARG C 1 190 ? -30.044 -7.614  59.607  1.00 25.39  ? 190 ARG C N   1 
ATOM   8357  C CA  . ARG C 1 190 ? -30.209 -8.997  59.994  1.00 24.14  ? 190 ARG C CA  1 
ATOM   8358  C C   . ARG C 1 190 ? -28.991 -9.816  59.582  1.00 26.48  ? 190 ARG C C   1 
ATOM   8359  O O   . ARG C 1 190 ? -28.520 -10.654 60.349  1.00 26.88  ? 190 ARG C O   1 
ATOM   8360  C CB  . ARG C 1 190 ? -31.429 -9.602  59.310  1.00 24.02  ? 190 ARG C CB  1 
ATOM   8361  C CG  . ARG C 1 190 ? -32.735 -8.923  59.664  1.00 27.53  ? 190 ARG C CG  1 
ATOM   8362  C CD  . ARG C 1 190 ? -33.050 -8.942  61.139  1.00 31.38  ? 190 ARG C CD  1 
ATOM   8363  N NE  . ARG C 1 190 ? -33.411 -10.277 61.570  1.00 37.13  ? 190 ARG C NE  1 
ATOM   8364  C CZ  . ARG C 1 190 ? -33.705 -10.622 62.826  1.00 39.06  ? 190 ARG C CZ  1 
ATOM   8365  N NH1 . ARG C 1 190 ? -33.953 -9.705  63.743  1.00 41.08  ? 190 ARG C NH1 1 
ATOM   8366  N NH2 . ARG C 1 190 ? -33.760 -11.895 63.169  1.00 35.61  ? 190 ARG C NH2 1 
ATOM   8367  N N   . MET C 1 191 ? -28.524 -9.601  58.343  1.00 28.55  ? 191 MET C N   1 
ATOM   8368  C CA  . MET C 1 191 ? -27.437 -10.388 57.794  1.00 28.03  ? 191 MET C CA  1 
ATOM   8369  C C   . MET C 1 191 ? -26.148 -10.136 58.578  1.00 28.35  ? 191 MET C C   1 
ATOM   8370  O O   . MET C 1 191 ? -25.322 -11.038 58.750  1.00 31.04  ? 191 MET C O   1 
ATOM   8371  C CB  . MET C 1 191 ? -27.271 -10.082 56.303  1.00 33.49  ? 191 MET C CB  1 
ATOM   8372  C CG  . MET C 1 191 ? -26.143 -9.112  55.971  1.00 43.28  ? 191 MET C CG  1 
ATOM   8373  S SD  . MET C 1 191 ? -25.904 -8.809  54.177  1.00 44.92  ? 191 MET C SD  1 
ATOM   8374  C CE  . MET C 1 191 ? -25.621 -10.498 53.669  1.00 45.02  ? 191 MET C CE  1 
ATOM   8375  N N   . LYS C 1 192 ? -25.984 -8.907  59.083  1.00 29.46  ? 192 LYS C N   1 
ATOM   8376  C CA  . LYS C 1 192 ? -24.761 -8.541  59.782  1.00 31.37  ? 192 LYS C CA  1 
ATOM   8377  C C   . LYS C 1 192 ? -24.874 -8.849  61.280  1.00 30.96  ? 192 LYS C C   1 
ATOM   8378  O O   . LYS C 1 192 ? -23.954 -9.403  61.877  1.00 28.52  ? 192 LYS C O   1 
ATOM   8379  C CB  . LYS C 1 192 ? -24.418 -7.063  59.558  1.00 30.13  ? 192 LYS C CB  1 
ATOM   8380  C CG  . LYS C 1 192 ? -23.585 -6.758  58.326  1.00 30.94  ? 192 LYS C CG  1 
ATOM   8381  C CD  . LYS C 1 192 ? -22.988 -5.348  58.292  1.00 38.34  ? 192 LYS C CD  1 
ATOM   8382  C CE  . LYS C 1 192 ? -21.804 -5.116  59.212  1.00 38.45  ? 192 LYS C CE  1 
ATOM   8383  N NZ  . LYS C 1 192 ? -20.520 -5.556  58.604  1.00 43.19  ? 192 LYS C NZ  1 
ATOM   8384  N N   . TYR C 1 193 ? -26.028 -8.550  61.880  1.00 33.03  ? 193 TYR C N   1 
ATOM   8385  C CA  . TYR C 1 193 ? -26.095 -8.334  63.317  1.00 32.16  ? 193 TYR C CA  1 
ATOM   8386  C C   . TYR C 1 193 ? -27.024 -9.317  64.011  1.00 32.50  ? 193 TYR C C   1 
ATOM   8387  O O   . TYR C 1 193 ? -26.993 -9.386  65.238  1.00 33.26  ? 193 TYR C O   1 
ATOM   8388  C CB  . TYR C 1 193 ? -26.570 -6.900  63.588  1.00 33.58  ? 193 TYR C CB  1 
ATOM   8389  C CG  . TYR C 1 193 ? -25.630 -5.842  63.084  1.00 32.71  ? 193 TYR C CG  1 
ATOM   8390  C CD1 . TYR C 1 193 ? -24.296 -5.841  63.494  1.00 32.01  ? 193 TYR C CD1 1 
ATOM   8391  C CD2 . TYR C 1 193 ? -26.057 -4.840  62.216  1.00 27.37  ? 193 TYR C CD2 1 
ATOM   8392  C CE1 . TYR C 1 193 ? -23.408 -4.872  63.040  1.00 33.87  ? 193 TYR C CE1 1 
ATOM   8393  C CE2 . TYR C 1 193 ? -25.169 -3.880  61.738  1.00 28.39  ? 193 TYR C CE2 1 
ATOM   8394  C CZ  . TYR C 1 193 ? -23.847 -3.885  62.158  1.00 33.22  ? 193 TYR C CZ  1 
ATOM   8395  O OH  . TYR C 1 193 ? -22.950 -2.919  61.732  1.00 40.42  ? 193 TYR C OH  1 
ATOM   8396  N N   . LYS C 1 194 ? -27.880 -10.025 63.257  1.00 39.59  ? 194 LYS C N   1 
ATOM   8397  C CA  . LYS C 1 194 ? -28.912 -10.868 63.861  1.00 43.11  ? 194 LYS C CA  1 
ATOM   8398  C C   . LYS C 1 194 ? -28.874 -12.291 63.323  1.00 43.76  ? 194 LYS C C   1 
ATOM   8399  O O   . LYS C 1 194 ? -29.916 -12.906 63.133  1.00 42.34  ? 194 LYS C O   1 
ATOM   8400  C CB  . LYS C 1 194 ? -30.302 -10.300 63.586  1.00 45.29  ? 194 LYS C CB  1 
ATOM   8401  C CG  . LYS C 1 194 ? -30.552 -8.947  64.240  1.00 45.30  ? 194 LYS C CG  1 
ATOM   8402  C CD  . LYS C 1 194 ? -30.838 -9.095  65.698  1.00 42.68  ? 194 LYS C CD  1 
ATOM   8403  C CE  . LYS C 1 194 ? -30.179 -8.038  66.530  1.00 50.05  ? 194 LYS C CE  1 
ATOM   8404  N NZ  . LYS C 1 194 ? -30.624 -8.214  67.925  1.00 58.84  ? 194 LYS C NZ  1 
ATOM   8405  N N   . SER C 1 195 ? -27.657 -12.805 63.119  1.00 50.55  ? 195 SER C N   1 
ATOM   8406  C CA  . SER C 1 195 ? -27.437 -14.201 62.766  1.00 50.18  ? 195 SER C CA  1 
ATOM   8407  C C   . SER C 1 195 ? -27.915 -14.528 61.351  1.00 42.09  ? 195 SER C C   1 
ATOM   8408  O O   . SER C 1 195 ? -28.095 -15.693 61.050  1.00 40.46  ? 195 SER C O   1 
ATOM   8409  C CB  . SER C 1 195 ? -28.054 -15.142 63.797  1.00 51.67  ? 195 SER C CB  1 
ATOM   8410  O OG  . SER C 1 195 ? -27.346 -15.055 65.038  1.00 56.44  ? 195 SER C OG  1 
ATOM   8411  N N   . ASP C 1 196 ? -28.101 -13.524 60.484  1.00 35.20  ? 196 ASP C N   1 
ATOM   8412  C CA  . ASP C 1 196 ? -28.486 -13.761 59.099  1.00 32.44  ? 196 ASP C CA  1 
ATOM   8413  C C   . ASP C 1 196 ? -29.744 -14.627 59.089  1.00 30.09  ? 196 ASP C C   1 
ATOM   8414  O O   . ASP C 1 196 ? -29.920 -15.460 58.195  1.00 29.68  ? 196 ASP C O   1 
ATOM   8415  C CB  . ASP C 1 196 ? -27.327 -14.364 58.272  1.00 34.81  ? 196 ASP C CB  1 
ATOM   8416  C CG  . ASP C 1 196 ? -27.365 -14.127 56.746  1.00 44.21  ? 196 ASP C CG  1 
ATOM   8417  O OD1 . ASP C 1 196 ? -28.186 -13.280 56.255  1.00 48.36  ? 196 ASP C OD1 1 
ATOM   8418  O OD2 . ASP C 1 196 ? -26.564 -14.780 55.986  1.00 46.06  ? 196 ASP C OD2 1 
ATOM   8419  N N   . THR C 1 197 ? -30.638 -14.446 60.072  1.00 27.34  ? 197 THR C N   1 
ATOM   8420  C CA  . THR C 1 197 ? -31.995 -14.937 59.895  1.00 29.42  ? 197 THR C CA  1 
ATOM   8421  C C   . THR C 1 197 ? -32.928 -13.756 59.619  1.00 31.22  ? 197 THR C C   1 
ATOM   8422  O O   . THR C 1 197 ? -32.844 -12.728 60.290  1.00 31.99  ? 197 THR C O   1 
ATOM   8423  C CB  . THR C 1 197 ? -32.472 -15.750 61.096  1.00 29.90  ? 197 THR C CB  1 
ATOM   8424  O OG1 . THR C 1 197 ? -32.662 -14.828 62.159  1.00 32.12  ? 197 THR C OG1 1 
ATOM   8425  C CG2 . THR C 1 197 ? -31.509 -16.838 61.522  1.00 32.55  ? 197 THR C CG2 1 
ATOM   8426  N N   . HIS C 1 198 ? -33.865 -13.955 58.693  1.00 30.69  ? 198 HIS C N   1 
ATOM   8427  C CA  . HIS C 1 198 ? -34.653 -12.877 58.106  1.00 32.98  ? 198 HIS C CA  1 
ATOM   8428  C C   . HIS C 1 198 ? -36.128 -13.114 58.396  1.00 32.31  ? 198 HIS C C   1 
ATOM   8429  O O   . HIS C 1 198 ? -36.666 -14.188 58.168  1.00 33.18  ? 198 HIS C O   1 
ATOM   8430  C CB  . HIS C 1 198 ? -34.386 -12.783 56.591  1.00 33.32  ? 198 HIS C CB  1 
ATOM   8431  C CG  . HIS C 1 198 ? -32.942 -12.536 56.292  1.00 39.95  ? 198 HIS C CG  1 
ATOM   8432  N ND1 . HIS C 1 198 ? -32.455 -11.290 56.025  1.00 36.55  ? 198 HIS C ND1 1 
ATOM   8433  C CD2 . HIS C 1 198 ? -31.866 -13.390 56.400  1.00 42.17  ? 198 HIS C CD2 1 
ATOM   8434  C CE1 . HIS C 1 198 ? -31.116 -11.364 55.937  1.00 41.91  ? 198 HIS C CE1 1 
ATOM   8435  N NE2 . HIS C 1 198 ? -30.731 -12.669 56.134  1.00 43.85  ? 198 HIS C NE2 1 
ATOM   8436  N N   . ILE C 1 199 ? -36.792 -12.076 58.884  1.00 35.22  ? 199 ILE C N   1 
ATOM   8437  C CA  . ILE C 1 199 ? -38.237 -12.069 59.006  1.00 36.87  ? 199 ILE C CA  1 
ATOM   8438  C C   . ILE C 1 199 ? -38.818 -11.534 57.699  1.00 36.05  ? 199 ILE C C   1 
ATOM   8439  O O   . ILE C 1 199 ? -38.376 -10.498 57.198  1.00 38.21  ? 199 ILE C O   1 
ATOM   8440  C CB  . ILE C 1 199 ? -38.617 -11.226 60.231  1.00 37.20  ? 199 ILE C CB  1 
ATOM   8441  C CG1 . ILE C 1 199 ? -37.946 -11.814 61.479  1.00 37.94  ? 199 ILE C CG1 1 
ATOM   8442  C CG2 . ILE C 1 199 ? -40.129 -11.076 60.366  1.00 34.33  ? 199 ILE C CG2 1 
ATOM   8443  C CD1 . ILE C 1 199 ? -37.730 -10.820 62.601  1.00 36.97  ? 199 ILE C CD1 1 
ATOM   8444  N N   . PRO C 1 200 ? -39.767 -12.246 57.057  1.00 37.81  ? 200 PRO C N   1 
ATOM   8445  C CA  . PRO C 1 200 ? -40.380 -11.744 55.822  1.00 45.19  ? 200 PRO C CA  1 
ATOM   8446  C C   . PRO C 1 200 ? -41.197 -10.468 56.054  1.00 46.62  ? 200 PRO C C   1 
ATOM   8447  O O   . PRO C 1 200 ? -41.743 -10.222 57.144  1.00 46.53  ? 200 PRO C O   1 
ATOM   8448  C CB  . PRO C 1 200 ? -41.288 -12.903 55.340  1.00 44.03  ? 200 PRO C CB  1 
ATOM   8449  C CG  . PRO C 1 200 ? -41.555 -13.736 56.592  1.00 43.72  ? 200 PRO C CG  1 
ATOM   8450  C CD  . PRO C 1 200 ? -40.342 -13.531 57.491  1.00 39.76  ? 200 PRO C CD  1 
ATOM   8451  N N   . SER C 1 201 ? -41.276 -9.655  55.006  1.00 48.92  ? 201 SER C N   1 
ATOM   8452  C CA  . SER C 1 201 ? -42.167 -8.508  55.011  1.00 54.30  ? 201 SER C CA  1 
ATOM   8453  C C   . SER C 1 201 ? -43.630 -8.955  55.158  1.00 56.15  ? 201 SER C C   1 
ATOM   8454  O O   . SER C 1 201 ? -44.046 -9.966  54.574  1.00 51.34  ? 201 SER C O   1 
ATOM   8455  C CB  . SER C 1 201 ? -41.944 -7.658  53.786  1.00 51.85  ? 201 SER C CB  1 
ATOM   8456  O OG  . SER C 1 201 ? -43.137 -6.996  53.421  1.00 52.17  ? 201 SER C OG  1 
ATOM   8457  N N   . ASN C 1 202 ? -44.387 -8.190  55.976  1.00 51.04  ? 202 ASN C N   1 
ATOM   8458  C CA  . ASN C 1 202 ? -45.813 -8.403  56.199  1.00 48.73  ? 202 ASN C CA  1 
ATOM   8459  C C   . ASN C 1 202 ? -46.616 -7.433  55.329  1.00 51.26  ? 202 ASN C C   1 
ATOM   8460  O O   . ASN C 1 202 ? -46.611 -6.223  55.572  1.00 56.47  ? 202 ASN C O   1 
ATOM   8461  C CB  . ASN C 1 202 ? -46.185 -8.223  57.668  1.00 45.21  ? 202 ASN C CB  1 
ATOM   8462  C CG  . ASN C 1 202 ? -47.619 -8.609  57.993  1.00 48.35  ? 202 ASN C CG  1 
ATOM   8463  O OD1 . ASN C 1 202 ? -48.438 -8.862  57.117  1.00 58.26  ? 202 ASN C OD1 1 
ATOM   8464  N ND2 . ASN C 1 202 ? -47.964 -8.630  59.261  1.00 46.51  ? 202 ASN C ND2 1 
ATOM   8465  N N   . PRO C 1 203 ? -47.346 -7.921  54.298  1.00 50.84  ? 203 PRO C N   1 
ATOM   8466  C CA  . PRO C 1 203 ? -48.138 -7.039  53.429  1.00 51.10  ? 203 PRO C CA  1 
ATOM   8467  C C   . PRO C 1 203 ? -49.274 -6.263  54.102  1.00 53.43  ? 203 PRO C C   1 
ATOM   8468  O O   . PRO C 1 203 ? -49.849 -5.376  53.482  1.00 64.53  ? 203 PRO C O   1 
ATOM   8469  C CB  . PRO C 1 203 ? -48.732 -8.009  52.406  1.00 50.38  ? 203 PRO C CB  1 
ATOM   8470  C CG  . PRO C 1 203 ? -48.732 -9.341  53.123  1.00 51.66  ? 203 PRO C CG  1 
ATOM   8471  C CD  . PRO C 1 203 ? -47.450 -9.335  53.918  1.00 47.83  ? 203 PRO C CD  1 
ATOM   8472  N N   . ASP C 1 204 ? -49.572 -6.548  55.374  1.00 53.54  ? 204 ASP C N   1 
ATOM   8473  C CA  . ASP C 1 204 ? -50.639 -5.849  56.078  1.00 57.16  ? 204 ASP C CA  1 
ATOM   8474  C C   . ASP C 1 204 ? -50.096 -4.654  56.864  1.00 61.61  ? 204 ASP C C   1 
ATOM   8475  O O   . ASP C 1 204 ? -50.855 -4.032  57.608  1.00 63.29  ? 204 ASP C O   1 
ATOM   8476  C CB  . ASP C 1 204 ? -51.395 -6.793  57.031  1.00 65.71  ? 204 ASP C CB  1 
ATOM   8477  C CG  . ASP C 1 204 ? -52.089 -7.987  56.377  1.00 69.43  ? 204 ASP C CG  1 
ATOM   8478  O OD1 . ASP C 1 204 ? -52.799 -7.793  55.371  1.00 63.75  ? 204 ASP C OD1 1 
ATOM   8479  O OD2 . ASP C 1 204 ? -51.953 -9.106  56.906  1.00 72.51  ? 204 ASP C OD2 1 
ATOM   8480  N N   . LEU C 1 205 ? -48.800 -4.325  56.717  1.00 55.84  ? 205 LEU C N   1 
ATOM   8481  C CA  . LEU C 1 205 ? -48.167 -3.329  57.579  1.00 49.19  ? 205 LEU C CA  1 
ATOM   8482  C C   . LEU C 1 205 ? -47.758 -2.099  56.773  1.00 47.48  ? 205 LEU C C   1 
ATOM   8483  O O   . LEU C 1 205 ? -47.425 -2.192  55.593  1.00 37.36  ? 205 LEU C O   1 
ATOM   8484  C CB  . LEU C 1 205 ? -46.941 -3.938  58.279  1.00 45.92  ? 205 LEU C CB  1 
ATOM   8485  C CG  . LEU C 1 205 ? -47.209 -4.801  59.514  1.00 46.73  ? 205 LEU C CG  1 
ATOM   8486  C CD1 . LEU C 1 205 ? -45.892 -5.269  60.123  1.00 45.46  ? 205 LEU C CD1 1 
ATOM   8487  C CD2 . LEU C 1 205 ? -48.068 -4.102  60.576  1.00 42.57  ? 205 LEU C CD2 1 
ATOM   8488  N N   . ASP C 1 206 ? -47.763 -0.935  57.432  1.00 51.16  ? 206 ASP C N   1 
ATOM   8489  C CA  . ASP C 1 206 ? -47.214 0.259   56.814  1.00 47.70  ? 206 ASP C CA  1 
ATOM   8490  C C   . ASP C 1 206 ? -45.686 0.150   56.775  1.00 50.37  ? 206 ASP C C   1 
ATOM   8491  O O   . ASP C 1 206 ? -45.103 -0.746  57.372  1.00 50.52  ? 206 ASP C O   1 
ATOM   8492  C CB  . ASP C 1 206 ? -47.686 1.515   57.538  1.00 45.73  ? 206 ASP C CB  1 
ATOM   8493  C CG  . ASP C 1 206 ? -46.920 1.831   58.807  1.00 53.05  ? 206 ASP C CG  1 
ATOM   8494  O OD1 . ASP C 1 206 ? -47.269 1.174   59.834  1.00 46.43  ? 206 ASP C OD1 1 
ATOM   8495  O OD2 . ASP C 1 206 ? -45.990 2.760   58.757  1.00 48.54  ? 206 ASP C OD2 1 
ATOM   8496  N N   . LEU C 1 207 ? -45.042 1.094   56.079  1.00 47.01  ? 207 LEU C N   1 
ATOM   8497  C CA  . LEU C 1 207 ? -43.600 1.109   55.893  1.00 46.75  ? 207 LEU C CA  1 
ATOM   8498  C C   . LEU C 1 207 ? -42.855 1.038   57.231  1.00 44.95  ? 207 LEU C C   1 
ATOM   8499  O O   . LEU C 1 207 ? -42.019 0.161   57.425  1.00 46.79  ? 207 LEU C O   1 
ATOM   8500  C CB  . LEU C 1 207 ? -43.278 2.378   55.107  1.00 49.64  ? 207 LEU C CB  1 
ATOM   8501  C CG  . LEU C 1 207 ? -41.818 2.563   54.721  1.00 52.34  ? 207 LEU C CG  1 
ATOM   8502  C CD1 . LEU C 1 207 ? -41.700 3.443   53.480  1.00 52.20  ? 207 LEU C CD1 1 
ATOM   8503  C CD2 . LEU C 1 207 ? -41.021 3.141   55.900  1.00 51.29  ? 207 LEU C CD2 1 
ATOM   8504  N N   . GLY C 1 208 ? -43.186 1.936   58.164  1.00 48.48  ? 208 GLY C N   1 
ATOM   8505  C CA  . GLY C 1 208 ? -42.595 1.948   59.494  1.00 46.93  ? 208 GLY C CA  1 
ATOM   8506  C C   . GLY C 1 208 ? -42.877 0.667   60.290  1.00 46.62  ? 208 GLY C C   1 
ATOM   8507  O O   . GLY C 1 208 ? -41.992 0.119   60.949  1.00 44.81  ? 208 GLY C O   1 
ATOM   8508  N N   . GLY C 1 209 ? -44.131 0.204   60.265  1.00 43.18  ? 209 GLY C N   1 
ATOM   8509  C CA  . GLY C 1 209 ? -44.500 -1.027  60.948  1.00 42.84  ? 209 GLY C CA  1 
ATOM   8510  C C   . GLY C 1 209 ? -43.737 -2.214  60.366  1.00 42.11  ? 209 GLY C C   1 
ATOM   8511  O O   . GLY C 1 209 ? -43.236 -3.075  61.087  1.00 41.48  ? 209 GLY C O   1 
ATOM   8512  N N   . ASP C 1 210 ? -43.623 -2.224  59.037  1.00 42.38  ? 210 ASP C N   1 
ATOM   8513  C CA  . ASP C 1 210 ? -43.012 -3.345  58.351  1.00 40.23  ? 210 ASP C CA  1 
ATOM   8514  C C   . ASP C 1 210 ? -41.499 -3.371  58.592  1.00 41.75  ? 210 ASP C C   1 
ATOM   8515  O O   . ASP C 1 210 ? -40.883 -4.438  58.633  1.00 36.13  ? 210 ASP C O   1 
ATOM   8516  C CB  . ASP C 1 210 ? -43.368 -3.351  56.871  1.00 39.89  ? 210 ASP C CB  1 
ATOM   8517  C CG  . ASP C 1 210 ? -42.915 -4.646  56.239  1.00 46.37  ? 210 ASP C CG  1 
ATOM   8518  O OD1 . ASP C 1 210 ? -43.039 -5.695  56.937  1.00 41.74  ? 210 ASP C OD1 1 
ATOM   8519  O OD2 . ASP C 1 210 ? -42.409 -4.597  55.071  1.00 54.10  ? 210 ASP C OD2 1 
ATOM   8520  N N   . PHE C 1 211 ? -40.899 -2.191  58.750  1.00 38.61  ? 211 PHE C N   1 
ATOM   8521  C CA  . PHE C 1 211 ? -39.475 -2.089  59.009  1.00 35.97  ? 211 PHE C CA  1 
ATOM   8522  C C   . PHE C 1 211 ? -39.158 -2.708  60.370  1.00 32.42  ? 211 PHE C C   1 
ATOM   8523  O O   . PHE C 1 211 ? -38.298 -3.583  60.477  1.00 32.27  ? 211 PHE C O   1 
ATOM   8524  C CB  . PHE C 1 211 ? -39.062 -0.619  58.863  1.00 36.93  ? 211 PHE C CB  1 
ATOM   8525  C CG  . PHE C 1 211 ? -37.613 -0.369  59.155  1.00 36.23  ? 211 PHE C CG  1 
ATOM   8526  C CD1 . PHE C 1 211 ? -36.643 -0.772  58.248  1.00 39.84  ? 211 PHE C CD1 1 
ATOM   8527  C CD2 . PHE C 1 211 ? -37.218 0.168   60.367  1.00 31.60  ? 211 PHE C CD2 1 
ATOM   8528  C CE1 . PHE C 1 211 ? -35.296 -0.584  58.527  1.00 40.26  ? 211 PHE C CE1 1 
ATOM   8529  C CE2 . PHE C 1 211 ? -35.874 0.344   60.655  1.00 32.72  ? 211 PHE C CE2 1 
ATOM   8530  C CZ  . PHE C 1 211 ? -34.917 -0.029  59.730  1.00 35.74  ? 211 PHE C CZ  1 
ATOM   8531  N N   . ALA C 1 212 ? -39.889 -2.285  61.404  1.00 36.43  ? 212 ALA C N   1 
ATOM   8532  C CA  . ALA C 1 212 ? -39.732 -2.811  62.765  1.00 39.88  ? 212 ALA C CA  1 
ATOM   8533  C C   . ALA C 1 212 ? -39.878 -4.332  62.787  1.00 37.40  ? 212 ALA C C   1 
ATOM   8534  O O   . ALA C 1 212 ? -39.162 -5.026  63.516  1.00 37.96  ? 212 ALA C O   1 
ATOM   8535  C CB  . ALA C 1 212 ? -40.755 -2.177  63.685  1.00 41.67  ? 212 ALA C CB  1 
ATOM   8536  N N   . ASN C 1 213 ? -40.861 -4.809  62.012  1.00 36.26  ? 213 ASN C N   1 
ATOM   8537  C CA  . ASN C 1 213 ? -41.136 -6.219  61.799  1.00 37.11  ? 213 ASN C CA  1 
ATOM   8538  C C   . ASN C 1 213 ? -39.887 -6.933  61.268  1.00 39.87  ? 213 ASN C C   1 
ATOM   8539  O O   . ASN C 1 213 ? -39.370 -7.857  61.911  1.00 43.04  ? 213 ASN C O   1 
ATOM   8540  C CB  . ASN C 1 213 ? -42.333 -6.355  60.850  1.00 40.86  ? 213 ASN C CB  1 
ATOM   8541  C CG  . ASN C 1 213 ? -42.591 -7.768  60.383  1.00 40.90  ? 213 ASN C CG  1 
ATOM   8542  O OD1 . ASN C 1 213 ? -42.981 -8.615  61.187  1.00 42.10  ? 213 ASN C OD1 1 
ATOM   8543  N ND2 . ASN C 1 213 ? -42.391 -8.011  59.095  1.00 36.69  ? 213 ASN C ND2 1 
ATOM   8544  N N   . MET C 1 214 ? -39.388 -6.477  60.115  1.00 34.90  ? 214 MET C N   1 
ATOM   8545  C CA  . MET C 1 214 ? -38.259 -7.115  59.464  1.00 36.94  ? 214 MET C CA  1 
ATOM   8546  C C   . MET C 1 214 ? -36.990 -6.964  60.306  1.00 39.27  ? 214 MET C C   1 
ATOM   8547  O O   . MET C 1 214 ? -36.073 -7.781  60.191  1.00 41.95  ? 214 MET C O   1 
ATOM   8548  C CB  . MET C 1 214 ? -38.007 -6.494  58.095  1.00 37.21  ? 214 MET C CB  1 
ATOM   8549  C CG  . MET C 1 214 ? -39.184 -6.642  57.174  1.00 44.82  ? 214 MET C CG  1 
ATOM   8550  S SD  . MET C 1 214 ? -38.910 -5.848  55.558  1.00 52.70  ? 214 MET C SD  1 
ATOM   8551  C CE  . MET C 1 214 ? -38.492 -7.351  54.671  1.00 56.29  ? 214 MET C CE  1 
ATOM   8552  N N   . MET C 1 215 ? -36.924 -5.910  61.125  1.00 33.57  ? 215 MET C N   1 
ATOM   8553  C CA  . MET C 1 215 ? -35.773 -5.712  61.983  1.00 36.04  ? 215 MET C CA  1 
ATOM   8554  C C   . MET C 1 215 ? -35.830 -6.701  63.141  1.00 33.88  ? 215 MET C C   1 
ATOM   8555  O O   . MET C 1 215 ? -34.815 -7.016  63.735  1.00 34.00  ? 215 MET C O   1 
ATOM   8556  C CB  . MET C 1 215 ? -35.758 -4.284  62.545  1.00 36.82  ? 215 MET C CB  1 
ATOM   8557  C CG  . MET C 1 215 ? -35.403 -3.229  61.508  1.00 40.77  ? 215 MET C CG  1 
ATOM   8558  S SD  . MET C 1 215 ? -33.635 -3.070  61.222  1.00 40.29  ? 215 MET C SD  1 
ATOM   8559  C CE  . MET C 1 215 ? -33.143 -2.397  62.808  1.00 41.82  ? 215 MET C CE  1 
ATOM   8560  N N   . GLY C 1 216 ? -37.044 -7.114  63.495  1.00 38.40  ? 216 GLY C N   1 
ATOM   8561  C CA  . GLY C 1 216 ? -37.271 -8.015  64.611  1.00 36.11  ? 216 GLY C CA  1 
ATOM   8562  C C   . GLY C 1 216 ? -37.507 -7.296  65.933  1.00 35.70  ? 216 GLY C C   1 
ATOM   8563  O O   . GLY C 1 216 ? -37.202 -7.869  66.963  1.00 39.52  ? 216 GLY C O   1 
ATOM   8564  N N   . ILE C 1 217 ? -38.051 -6.068  65.922  1.00 41.25  ? 217 ILE C N   1 
ATOM   8565  C CA  . ILE C 1 217 ? -38.147 -5.269  67.148  1.00 41.88  ? 217 ILE C CA  1 
ATOM   8566  C C   . ILE C 1 217 ? -39.618 -4.954  67.433  1.00 41.56  ? 217 ILE C C   1 
ATOM   8567  O O   . ILE C 1 217 ? -40.361 -4.585  66.514  1.00 37.04  ? 217 ILE C O   1 
ATOM   8568  C CB  . ILE C 1 217 ? -37.248 -4.010  67.031  1.00 41.13  ? 217 ILE C CB  1 
ATOM   8569  C CG1 . ILE C 1 217 ? -35.818 -4.383  66.608  1.00 39.85  ? 217 ILE C CG1 1 
ATOM   8570  C CG2 . ILE C 1 217 ? -37.241 -3.184  68.307  1.00 35.75  ? 217 ILE C CG2 1 
ATOM   8571  C CD1 . ILE C 1 217 ? -34.898 -3.210  66.413  1.00 38.54  ? 217 ILE C CD1 1 
ATOM   8572  N N   . ASP C 1 218 ? -40.020 -5.118  68.709  1.00 48.16  ? 218 ASP C N   1 
ATOM   8573  C CA  . ASP C 1 218 ? -41.424 -4.983  69.092  1.00 59.91  ? 218 ASP C CA  1 
ATOM   8574  C C   . ASP C 1 218 ? -41.823 -3.520  69.257  1.00 55.58  ? 218 ASP C C   1 
ATOM   8575  O O   . ASP C 1 218 ? -40.945 -2.662  69.407  1.00 47.57  ? 218 ASP C O   1 
ATOM   8576  C CB  . ASP C 1 218 ? -41.774 -5.668  70.416  1.00 63.38  ? 218 ASP C CB  1 
ATOM   8577  C CG  . ASP C 1 218 ? -41.669 -7.180  70.417  1.00 80.15  ? 218 ASP C CG  1 
ATOM   8578  O OD1 . ASP C 1 218 ? -42.214 -7.841  69.477  1.00 81.59  ? 218 ASP C OD1 1 
ATOM   8579  O OD2 . ASP C 1 218 ? -41.061 -7.682  71.376  1.00 93.15  ? 218 ASP C OD2 1 
ATOM   8580  N N   . LYS C 1 219 ? -43.159 -3.293  69.271  1.00 52.52  ? 219 LYS C N   1 
ATOM   8581  C CA  . LYS C 1 219 ? -43.752 -1.995  69.569  1.00 50.96  ? 219 LYS C CA  1 
ATOM   8582  C C   . LYS C 1 219 ? -43.156 -1.490  70.882  1.00 48.09  ? 219 LYS C C   1 
ATOM   8583  O O   . LYS C 1 219 ? -42.959 -2.269  71.815  1.00 39.18  ? 219 LYS C O   1 
ATOM   8584  C CB  . LYS C 1 219 ? -45.274 -2.052  69.777  1.00 56.54  ? 219 LYS C CB  1 
ATOM   8585  C CG  . LYS C 1 219 ? -46.176 -2.401  68.595  1.00 59.10  ? 219 LYS C CG  1 
ATOM   8586  C CD  . LYS C 1 219 ? -46.403 -3.890  68.393  1.00 69.00  ? 219 LYS C CD  1 
ATOM   8587  C CE  . LYS C 1 219 ? -47.820 -4.279  67.993  1.00 71.65  ? 219 LYS C CE  1 
ATOM   8588  N NZ  . LYS C 1 219 ? -48.404 -3.382  66.964  1.00 65.96  ? 219 LYS C NZ  1 
ATOM   8589  N N   . PRO C 1 220 ? -42.881 -0.177  71.043  1.00 46.82  ? 220 PRO C N   1 
ATOM   8590  C CA  . PRO C 1 220 ? -43.224 0.840   70.048  1.00 48.72  ? 220 PRO C CA  1 
ATOM   8591  C C   . PRO C 1 220 ? -42.138 1.214   69.040  1.00 48.81  ? 220 PRO C C   1 
ATOM   8592  O O   . PRO C 1 220 ? -42.087 2.346   68.565  1.00 56.48  ? 220 PRO C O   1 
ATOM   8593  C CB  . PRO C 1 220 ? -43.445 2.039   70.984  1.00 51.61  ? 220 PRO C CB  1 
ATOM   8594  C CG  . PRO C 1 220 ? -42.338 1.883   72.032  1.00 52.82  ? 220 PRO C CG  1 
ATOM   8595  C CD  . PRO C 1 220 ? -42.210 0.388   72.229  1.00 48.19  ? 220 PRO C CD  1 
ATOM   8596  N N   . TYR C 1 221 ? -41.253 0.275   68.711  1.00 43.40  ? 221 TYR C N   1 
ATOM   8597  C CA  . TYR C 1 221 ? -40.206 0.578   67.760  1.00 37.59  ? 221 TYR C CA  1 
ATOM   8598  C C   . TYR C 1 221 ? -40.836 1.020   66.437  1.00 37.17  ? 221 TYR C C   1 
ATOM   8599  O O   . TYR C 1 221 ? -40.266 1.859   65.735  1.00 44.51  ? 221 TYR C O   1 
ATOM   8600  C CB  . TYR C 1 221 ? -39.228 -0.584  67.581  1.00 32.79  ? 221 TYR C CB  1 
ATOM   8601  C CG  . TYR C 1 221 ? -37.993 -0.149  66.828  1.00 31.78  ? 221 TYR C CG  1 
ATOM   8602  C CD1 . TYR C 1 221 ? -37.019 0.602   67.456  1.00 30.89  ? 221 TYR C CD1 1 
ATOM   8603  C CD2 . TYR C 1 221 ? -37.836 -0.406  65.470  1.00 31.31  ? 221 TYR C CD2 1 
ATOM   8604  C CE1 . TYR C 1 221 ? -35.906 1.056   66.774  1.00 29.46  ? 221 TYR C CE1 1 
ATOM   8605  C CE2 . TYR C 1 221 ? -36.733 0.044   64.771  1.00 32.02  ? 221 TYR C CE2 1 
ATOM   8606  C CZ  . TYR C 1 221 ? -35.764 0.782   65.423  1.00 29.27  ? 221 TYR C CZ  1 
ATOM   8607  O OH  . TYR C 1 221 ? -34.670 1.248   64.710  1.00 34.12  ? 221 TYR C OH  1 
ATOM   8608  N N   . ASP C 1 222 ? -41.989 0.450   66.078  1.00 36.60  ? 222 ASP C N   1 
ATOM   8609  C CA  . ASP C 1 222 ? -42.733 0.893   64.901  1.00 44.00  ? 222 ASP C CA  1 
ATOM   8610  C C   . ASP C 1 222 ? -42.860 2.423   64.910  1.00 40.69  ? 222 ASP C C   1 
ATOM   8611  O O   . ASP C 1 222 ? -42.653 3.067   63.885  1.00 42.88  ? 222 ASP C O   1 
ATOM   8612  C CB  . ASP C 1 222 ? -44.100 0.188   64.785  1.00 52.24  ? 222 ASP C CB  1 
ATOM   8613  C CG  . ASP C 1 222 ? -45.079 0.369   65.961  1.00 60.90  ? 222 ASP C CG  1 
ATOM   8614  O OD1 . ASP C 1 222 ? -44.626 0.474   67.167  1.00 52.87  ? 222 ASP C OD1 1 
ATOM   8615  O OD2 . ASP C 1 222 ? -46.317 0.359   65.687  1.00 57.91  ? 222 ASP C OD2 1 
ATOM   8616  N N   . ASP C 1 223 ? -43.187 3.012   66.063  1.00 36.27  ? 223 ASP C N   1 
ATOM   8617  C CA  . ASP C 1 223 ? -43.410 4.450   66.144  1.00 41.23  ? 223 ASP C CA  1 
ATOM   8618  C C   . ASP C 1 223 ? -42.094 5.199   66.131  1.00 37.20  ? 223 ASP C C   1 
ATOM   8619  O O   . ASP C 1 223 ? -42.017 6.239   65.500  1.00 43.91  ? 223 ASP C O   1 
ATOM   8620  C CB  . ASP C 1 223 ? -44.217 4.832   67.388  1.00 45.61  ? 223 ASP C CB  1 
ATOM   8621  C CG  . ASP C 1 223 ? -45.711 4.649   67.203  1.00 51.15  ? 223 ASP C CG  1 
ATOM   8622  O OD1 . ASP C 1 223 ? -46.178 4.609   66.020  1.00 52.84  ? 223 ASP C OD1 1 
ATOM   8623  O OD2 . ASP C 1 223 ? -46.390 4.534   68.235  1.00 52.19  ? 223 ASP C OD2 1 
ATOM   8624  N N   . VAL C 1 224 ? -41.107 4.680   66.871  1.00 35.81  ? 224 VAL C N   1 
ATOM   8625  C CA  . VAL C 1 224 ? -39.731 5.145   66.824  1.00 36.82  ? 224 VAL C CA  1 
ATOM   8626  C C   . VAL C 1 224 ? -39.260 5.297   65.378  1.00 38.74  ? 224 VAL C C   1 
ATOM   8627  O O   . VAL C 1 224 ? -38.606 6.278   65.069  1.00 43.32  ? 224 VAL C O   1 
ATOM   8628  C CB  . VAL C 1 224 ? -38.784 4.171   67.544  1.00 37.04  ? 224 VAL C CB  1 
ATOM   8629  C CG1 . VAL C 1 224 ? -37.334 4.592   67.382  1.00 36.95  ? 224 VAL C CG1 1 
ATOM   8630  C CG2 . VAL C 1 224 ? -39.119 4.031   69.012  1.00 39.76  ? 224 VAL C CG2 1 
ATOM   8631  N N   . ALA C 1 225 ? -39.542 4.294   64.533  1.00 39.62  ? 225 ALA C N   1 
ATOM   8632  C CA  . ALA C 1 225 ? -39.100 4.249   63.148  1.00 39.85  ? 225 ALA C CA  1 
ATOM   8633  C C   . ALA C 1 225 ? -39.796 5.305   62.303  1.00 39.19  ? 225 ALA C C   1 
ATOM   8634  O O   . ALA C 1 225 ? -39.135 6.025   61.550  1.00 42.81  ? 225 ALA C O   1 
ATOM   8635  C CB  . ALA C 1 225 ? -39.366 2.884   62.588  1.00 41.19  ? 225 ALA C CB  1 
ATOM   8636  N N   . ARG C 1 226 ? -41.125 5.344   62.408  1.00 37.18  ? 226 ARG C N   1 
ATOM   8637  C CA  . ARG C 1 226 ? -41.941 6.369   61.751  1.00 43.26  ? 226 ARG C CA  1 
ATOM   8638  C C   . ARG C 1 226 ? -41.425 7.779   62.073  1.00 39.86  ? 226 ARG C C   1 
ATOM   8639  O O   . ARG C 1 226 ? -41.111 8.585   61.198  1.00 39.66  ? 226 ARG C O   1 
ATOM   8640  C CB  . ARG C 1 226 ? -43.407 6.244   62.182  1.00 37.16  ? 226 ARG C CB  1 
ATOM   8641  C CG  . ARG C 1 226 ? -44.108 5.024   61.614  1.00 37.63  ? 226 ARG C CG  1 
ATOM   8642  C CD  . ARG C 1 226 ? -45.311 4.624   62.445  1.00 37.52  ? 226 ARG C CD  1 
ATOM   8643  N NE  . ARG C 1 226 ? -45.979 3.410   61.985  1.00 39.91  ? 226 ARG C NE  1 
ATOM   8644  C CZ  . ARG C 1 226 ? -46.467 2.464   62.785  1.00 43.96  ? 226 ARG C CZ  1 
ATOM   8645  N NH1 . ARG C 1 226 ? -46.448 2.623   64.100  1.00 43.65  ? 226 ARG C NH1 1 
ATOM   8646  N NH2 . ARG C 1 226 ? -47.005 1.375   62.258  1.00 41.69  ? 226 ARG C NH2 1 
ATOM   8647  N N   . LEU C 1 227 ? -41.335 8.079   63.356  1.00 36.66  ? 227 LEU C N   1 
ATOM   8648  C CA  . LEU C 1 227 ? -40.870 9.382   63.766  1.00 36.57  ? 227 LEU C CA  1 
ATOM   8649  C C   . LEU C 1 227 ? -39.504 9.661   63.153  1.00 35.54  ? 227 LEU C C   1 
ATOM   8650  O O   . LEU C 1 227 ? -39.317 10.671  62.479  1.00 41.77  ? 227 LEU C O   1 
ATOM   8651  C CB  . LEU C 1 227 ? -40.819 9.438   65.288  1.00 35.53  ? 227 LEU C CB  1 
ATOM   8652  C CG  . LEU C 1 227 ? -40.287 10.762  65.832  1.00 40.41  ? 227 LEU C CG  1 
ATOM   8653  C CD1 . LEU C 1 227 ? -41.139 11.940  65.363  1.00 41.42  ? 227 LEU C CD1 1 
ATOM   8654  C CD2 . LEU C 1 227 ? -40.222 10.738  67.344  1.00 43.75  ? 227 LEU C CD2 1 
ATOM   8655  N N   . TYR C 1 228 ? -38.570 8.746   63.383  1.00 37.21  ? 228 TYR C N   1 
ATOM   8656  C CA  . TYR C 1 228 ? -37.177 8.939   63.005  1.00 40.03  ? 228 TYR C CA  1 
ATOM   8657  C C   . TYR C 1 228 ? -37.085 9.247   61.514  1.00 30.63  ? 228 TYR C C   1 
ATOM   8658  O O   . TYR C 1 228 ? -36.324 10.109  61.094  1.00 39.41  ? 228 TYR C O   1 
ATOM   8659  C CB  . TYR C 1 228 ? -36.315 7.724   63.407  1.00 44.46  ? 228 TYR C CB  1 
ATOM   8660  C CG  . TYR C 1 228 ? -34.860 7.835   63.031  1.00 42.12  ? 228 TYR C CG  1 
ATOM   8661  C CD1 . TYR C 1 228 ? -34.462 7.749   61.702  1.00 43.88  ? 228 TYR C CD1 1 
ATOM   8662  C CD2 . TYR C 1 228 ? -33.886 8.081   63.979  1.00 44.63  ? 228 TYR C CD2 1 
ATOM   8663  C CE1 . TYR C 1 228 ? -33.141 7.917   61.321  1.00 44.04  ? 228 TYR C CE1 1 
ATOM   8664  C CE2 . TYR C 1 228 ? -32.553 8.228   63.618  1.00 47.32  ? 228 TYR C CE2 1 
ATOM   8665  C CZ  . TYR C 1 228 ? -32.180 8.149   62.284  1.00 46.82  ? 228 TYR C CZ  1 
ATOM   8666  O OH  . TYR C 1 228 ? -30.877 8.304   61.874  1.00 57.57  ? 228 TYR C OH  1 
ATOM   8667  N N   . PHE C 1 229 ? -37.833 8.533   60.703  1.00 31.01  ? 229 PHE C N   1 
ATOM   8668  C CA  . PHE C 1 229 ? -37.693 8.703   59.264  1.00 33.43  ? 229 PHE C CA  1 
ATOM   8669  C C   . PHE C 1 229 ? -38.279 10.038  58.830  1.00 34.00  ? 229 PHE C C   1 
ATOM   8670  O O   . PHE C 1 229 ? -37.740 10.693  57.939  1.00 34.59  ? 229 PHE C O   1 
ATOM   8671  C CB  . PHE C 1 229 ? -38.405 7.576   58.527  1.00 36.43  ? 229 PHE C CB  1 
ATOM   8672  C CG  . PHE C 1 229 ? -37.776 6.214   58.635  1.00 37.40  ? 229 PHE C CG  1 
ATOM   8673  C CD1 . PHE C 1 229 ? -36.412 6.066   58.853  1.00 38.46  ? 229 PHE C CD1 1 
ATOM   8674  C CD2 . PHE C 1 229 ? -38.567 5.075   58.536  1.00 40.72  ? 229 PHE C CD2 1 
ATOM   8675  C CE1 . PHE C 1 229 ? -35.847 4.805   58.961  1.00 36.02  ? 229 PHE C CE1 1 
ATOM   8676  C CE2 . PHE C 1 229 ? -38.000 3.813   58.630  1.00 38.83  ? 229 PHE C CE2 1 
ATOM   8677  C CZ  . PHE C 1 229 ? -36.643 3.684   58.843  1.00 38.63  ? 229 PHE C CZ  1 
ATOM   8678  N N   . ILE C 1 230 ? -39.379 10.429  59.485  1.00 37.99  ? 230 ILE C N   1 
ATOM   8679  C CA  . ILE C 1 230 ? -40.019 11.715  59.224  1.00 42.54  ? 230 ILE C CA  1 
ATOM   8680  C C   . ILE C 1 230 ? -39.062 12.850  59.607  1.00 37.90  ? 230 ILE C C   1 
ATOM   8681  O O   . ILE C 1 230 ? -38.847 13.750  58.806  1.00 32.58  ? 230 ILE C O   1 
ATOM   8682  C CB  . ILE C 1 230 ? -41.400 11.785  59.932  1.00 47.63  ? 230 ILE C CB  1 
ATOM   8683  C CG1 . ILE C 1 230 ? -42.456 10.968  59.179  1.00 40.99  ? 230 ILE C CG1 1 
ATOM   8684  C CG2 . ILE C 1 230 ? -41.878 13.220  60.129  1.00 54.75  ? 230 ILE C CG2 1 
ATOM   8685  C CD1 . ILE C 1 230 ? -43.612 10.502  60.036  1.00 38.59  ? 230 ILE C CD1 1 
ATOM   8686  N N   . LEU C 1 231 ? -38.441 12.778  60.795  1.00 36.57  ? 231 LEU C N   1 
ATOM   8687  C CA  . LEU C 1 231 ? -37.547 13.822  61.263  1.00 31.23  ? 231 LEU C CA  1 
ATOM   8688  C C   . LEU C 1 231 ? -36.350 13.981  60.345  1.00 32.53  ? 231 LEU C C   1 
ATOM   8689  O O   . LEU C 1 231 ? -35.885 15.109  60.097  1.00 37.66  ? 231 LEU C O   1 
ATOM   8690  C CB  . LEU C 1 231 ? -37.110 13.489  62.686  1.00 33.46  ? 231 LEU C CB  1 
ATOM   8691  C CG  . LEU C 1 231 ? -38.230 13.492  63.745  1.00 34.32  ? 231 LEU C CG  1 
ATOM   8692  C CD1 . LEU C 1 231 ? -37.675 13.688  65.151  1.00 32.83  ? 231 LEU C CD1 1 
ATOM   8693  C CD2 . LEU C 1 231 ? -39.260 14.571  63.485  1.00 37.05  ? 231 LEU C CD2 1 
ATOM   8694  N N   . HIS C 1 232 ? -35.854 12.863  59.808  1.00 34.90  ? 232 HIS C N   1 
ATOM   8695  C CA  . HIS C 1 232 ? -34.630 12.910  59.019  1.00 33.58  ? 232 HIS C CA  1 
ATOM   8696  C C   . HIS C 1 232 ? -34.942 13.012  57.526  1.00 33.52  ? 232 HIS C C   1 
ATOM   8697  O O   . HIS C 1 232 ? -34.024 12.945  56.707  1.00 35.72  ? 232 HIS C O   1 
ATOM   8698  C CB  . HIS C 1 232 ? -33.730 11.713  59.341  1.00 36.43  ? 232 HIS C CB  1 
ATOM   8699  C CG  . HIS C 1 232 ? -33.172 11.678  60.735  1.00 41.58  ? 232 HIS C CG  1 
ATOM   8700  N ND1 . HIS C 1 232 ? -33.893 11.276  61.845  1.00 47.33  ? 232 HIS C ND1 1 
ATOM   8701  C CD2 . HIS C 1 232 ? -31.901 11.985  61.150  1.00 44.51  ? 232 HIS C CD2 1 
ATOM   8702  C CE1 . HIS C 1 232 ? -33.106 11.368  62.917  1.00 53.38  ? 232 HIS C CE1 1 
ATOM   8703  N NE2 . HIS C 1 232 ? -31.853 11.802  62.503  1.00 49.43  ? 232 HIS C NE2 1 
ATOM   8704  N N   . SER C 1 233 ? -36.212 13.265  57.172  1.00 29.64  ? 233 SER C N   1 
ATOM   8705  C CA  . SER C 1 233 ? -36.656 13.211  55.781  1.00 28.59  ? 233 SER C CA  1 
ATOM   8706  C C   . SER C 1 233 ? -36.023 14.280  54.893  1.00 30.65  ? 233 SER C C   1 
ATOM   8707  O O   . SER C 1 233 ? -35.740 13.999  53.723  1.00 30.86  ? 233 SER C O   1 
ATOM   8708  C CB  . SER C 1 233 ? -38.149 13.294  55.697  1.00 27.53  ? 233 SER C CB  1 
ATOM   8709  O OG  . SER C 1 233 ? -38.620 14.416  56.441  1.00 27.53  ? 233 SER C OG  1 
ATOM   8710  N N   . ASP C 1 234 ? -35.878 15.516  55.375  1.00 33.00  ? 234 ASP C N   1 
ATOM   8711  C CA  . ASP C 1 234 ? -35.214 16.536  54.571  1.00 40.38  ? 234 ASP C CA  1 
ATOM   8712  C C   . ASP C 1 234 ? -34.592 17.558  55.516  1.00 38.66  ? 234 ASP C C   1 
ATOM   8713  O O   . ASP C 1 234 ? -34.943 17.577  56.700  1.00 41.64  ? 234 ASP C O   1 
ATOM   8714  C CB  . ASP C 1 234 ? -36.119 17.154  53.479  1.00 46.06  ? 234 ASP C CB  1 
ATOM   8715  C CG  . ASP C 1 234 ? -35.393 17.567  52.171  1.00 60.31  ? 234 ASP C CG  1 
ATOM   8716  O OD1 . ASP C 1 234 ? -34.561 16.752  51.629  1.00 60.81  ? 234 ASP C OD1 1 
ATOM   8717  O OD2 . ASP C 1 234 ? -35.624 18.713  51.651  1.00 58.40  ? 234 ASP C OD2 1 
ATOM   8718  N N   . HIS C 1 235 ? -33.603 18.296  54.979  1.00 37.10  ? 235 HIS C N   1 
ATOM   8719  C CA  . HIS C 1 235 ? -32.966 19.432  55.648  1.00 44.58  ? 235 HIS C CA  1 
ATOM   8720  C C   . HIS C 1 235 ? -32.361 20.360  54.593  1.00 43.70  ? 235 HIS C C   1 
ATOM   8721  O O   . HIS C 1 235 ? -31.154 20.588  54.571  1.00 45.75  ? 235 HIS C O   1 
ATOM   8722  C CB  . HIS C 1 235 ? -31.921 18.991  56.677  1.00 44.91  ? 235 HIS C CB  1 
ATOM   8723  C CG  . HIS C 1 235 ? -31.916 19.789  57.943  1.00 47.66  ? 235 HIS C CG  1 
ATOM   8724  N ND1 . HIS C 1 235 ? -30.831 20.485  58.404  1.00 49.36  ? 235 HIS C ND1 1 
ATOM   8725  C CD2 . HIS C 1 235 ? -32.902 19.950  58.870  1.00 52.75  ? 235 HIS C CD2 1 
ATOM   8726  C CE1 . HIS C 1 235 ? -31.139 21.063  59.568  1.00 55.80  ? 235 HIS C CE1 1 
ATOM   8727  N NE2 . HIS C 1 235 ? -32.425 20.745  59.885  1.00 56.18  ? 235 HIS C NE2 1 
ATOM   8728  N N   . GLU C 1 236 ? -33.228 20.863  53.724  1.00 43.17  ? 236 GLU C N   1 
ATOM   8729  C CA  . GLU C 1 236 ? -32.756 21.711  52.612  1.00 46.03  ? 236 GLU C CA  1 
ATOM   8730  C C   . GLU C 1 236 ? -31.934 20.836  51.671  1.00 40.67  ? 236 GLU C C   1 
ATOM   8731  O O   . GLU C 1 236 ? -31.686 19.675  51.979  1.00 48.74  ? 236 GLU C O   1 
ATOM   8732  C CB  . GLU C 1 236 ? -31.920 22.889  53.124  1.00 62.27  ? 236 GLU C CB  1 
ATOM   8733  C CG  . GLU C 1 236 ? -32.509 24.271  52.948  1.00 70.93  ? 236 GLU C CG  1 
ATOM   8734  C CD  . GLU C 1 236 ? -31.608 25.399  53.413  1.00 76.36  ? 236 GLU C CD  1 
ATOM   8735  O OE1 . GLU C 1 236 ? -32.143 26.434  53.849  1.00 65.97  ? 236 GLU C OE1 1 
ATOM   8736  O OE2 . GLU C 1 236 ? -30.377 25.238  53.333  1.00 63.61  ? 236 GLU C OE2 1 
ATOM   8737  N N   . SER C 1 237 ? -31.574 21.375  50.530  1.00 37.97  ? 237 SER C N   1 
ATOM   8738  C CA  . SER C 1 237 ? -30.741 20.694  49.548  1.00 39.73  ? 237 SER C CA  1 
ATOM   8739  C C   . SER C 1 237 ? -29.259 21.087  49.635  1.00 43.95  ? 237 SER C C   1 
ATOM   8740  O O   . SER C 1 237 ? -28.495 20.791  48.716  1.00 44.82  ? 237 SER C O   1 
ATOM   8741  C CB  . SER C 1 237 ? -31.280 20.886  48.141  1.00 43.76  ? 237 SER C CB  1 
ATOM   8742  O OG  . SER C 1 237 ? -31.134 22.229  47.687  1.00 45.00  ? 237 SER C OG  1 
ATOM   8743  N N   . GLY C 1 238 ? -28.818 21.704  50.740  1.00 45.55  ? 238 GLY C N   1 
ATOM   8744  C CA  . GLY C 1 238 ? -27.437 22.166  50.843  1.00 45.82  ? 238 GLY C CA  1 
ATOM   8745  C C   . GLY C 1 238 ? -26.506 21.172  51.548  1.00 45.23  ? 238 GLY C C   1 
ATOM   8746  O O   . GLY C 1 238 ? -25.278 21.212  51.374  1.00 42.48  ? 238 GLY C O   1 
ATOM   8747  N N   . ASN C 1 239 ? -27.110 20.281  52.346  1.00 39.01  ? 239 ASN C N   1 
ATOM   8748  C CA  . ASN C 1 239 ? -26.362 19.257  53.047  1.00 36.59  ? 239 ASN C CA  1 
ATOM   8749  C C   . ASN C 1 239 ? -25.738 18.315  52.010  1.00 37.66  ? 239 ASN C C   1 
ATOM   8750  O O   . ASN C 1 239 ? -26.224 18.166  50.882  1.00 31.66  ? 239 ASN C O   1 
ATOM   8751  C CB  . ASN C 1 239 ? -27.237 18.586  54.111  1.00 33.97  ? 239 ASN C CB  1 
ATOM   8752  C CG  . ASN C 1 239 ? -28.368 17.766  53.527  1.00 39.03  ? 239 ASN C CG  1 
ATOM   8753  O OD1 . ASN C 1 239 ? -28.147 16.631  53.082  1.00 35.17  ? 239 ASN C OD1 1 
ATOM   8754  N ND2 . ASN C 1 239 ? -29.575 18.332  53.544  1.00 37.21  ? 239 ASN C ND2 1 
ATOM   8755  N N   . VAL C 1 240 ? -24.639 17.667  52.414  1.00 40.31  ? 240 VAL C N   1 
ATOM   8756  C CA  . VAL C 1 240 ? -23.792 16.931  51.491  1.00 36.21  ? 240 VAL C CA  1 
ATOM   8757  C C   . VAL C 1 240 ? -24.597 15.848  50.788  1.00 35.23  ? 240 VAL C C   1 
ATOM   8758  O O   . VAL C 1 240 ? -24.452 15.717  49.581  1.00 38.81  ? 240 VAL C O   1 
ATOM   8759  C CB  . VAL C 1 240 ? -22.578 16.316  52.211  1.00 39.92  ? 240 VAL C CB  1 
ATOM   8760  C CG1 . VAL C 1 240 ? -21.859 15.287  51.347  1.00 41.14  ? 240 VAL C CG1 1 
ATOM   8761  C CG2 . VAL C 1 240 ? -21.600 17.385  52.670  1.00 42.12  ? 240 VAL C CG2 1 
ATOM   8762  N N   . SER C 1 241 ? -25.411 15.072  51.528  1.00 35.62  ? 241 SER C N   1 
ATOM   8763  C CA  . SER C 1 241 ? -26.142 13.943  50.961  1.00 35.63  ? 241 SER C CA  1 
ATOM   8764  C C   . SER C 1 241 ? -27.189 14.438  49.954  1.00 33.13  ? 241 SER C C   1 
ATOM   8765  O O   . SER C 1 241 ? -27.197 13.997  48.802  1.00 38.03  ? 241 SER C O   1 
ATOM   8766  C CB  . SER C 1 241 ? -26.727 12.990  52.030  1.00 34.55  ? 241 SER C CB  1 
ATOM   8767  O OG  . SER C 1 241 ? -27.671 13.617  52.903  1.00 31.69  ? 241 SER C OG  1 
ATOM   8768  N N   . ALA C 1 242 ? -28.027 15.404  50.347  1.00 36.33  ? 242 ALA C N   1 
ATOM   8769  C CA  . ALA C 1 242 ? -29.047 15.934  49.450  1.00 32.19  ? 242 ALA C CA  1 
ATOM   8770  C C   . ALA C 1 242 ? -28.387 16.607  48.249  1.00 31.66  ? 242 ALA C C   1 
ATOM   8771  O O   . ALA C 1 242 ? -28.791 16.371  47.103  1.00 36.02  ? 242 ALA C O   1 
ATOM   8772  C CB  . ALA C 1 242 ? -29.949 16.870  50.204  1.00 31.07  ? 242 ALA C CB  1 
ATOM   8773  N N   . HIS C 1 243 ? -27.352 17.419  48.518  1.00 29.55  ? 243 HIS C N   1 
ATOM   8774  C CA  . HIS C 1 243 ? -26.645 18.163  47.477  1.00 30.01  ? 243 HIS C CA  1 
ATOM   8775  C C   . HIS C 1 243 ? -25.972 17.225  46.490  1.00 27.66  ? 243 HIS C C   1 
ATOM   8776  O O   . HIS C 1 243 ? -25.935 17.534  45.316  1.00 29.69  ? 243 HIS C O   1 
ATOM   8777  C CB  . HIS C 1 243 ? -25.595 19.087  48.117  1.00 33.34  ? 243 HIS C CB  1 
ATOM   8778  C CG  . HIS C 1 243 ? -24.815 19.974  47.185  1.00 35.70  ? 243 HIS C CG  1 
ATOM   8779  N ND1 . HIS C 1 243 ? -23.632 20.580  47.565  1.00 39.36  ? 243 HIS C ND1 1 
ATOM   8780  C CD2 . HIS C 1 243 ? -25.059 20.327  45.876  1.00 33.87  ? 243 HIS C CD2 1 
ATOM   8781  C CE1 . HIS C 1 243 ? -23.182 21.286  46.516  1.00 38.75  ? 243 HIS C CE1 1 
ATOM   8782  N NE2 . HIS C 1 243 ? -24.052 21.150  45.457  1.00 29.18  ? 243 HIS C NE2 1 
ATOM   8783  N N   . THR C 1 244 ? -25.415 16.103  46.970  1.00 27.48  ? 244 THR C N   1 
ATOM   8784  C CA  . THR C 1 244 ? -24.766 15.151  46.083  1.00 29.48  ? 244 THR C CA  1 
ATOM   8785  C C   . THR C 1 244 ? -25.765 14.538  45.097  1.00 29.58  ? 244 THR C C   1 
ATOM   8786  O O   . THR C 1 244 ? -25.498 14.427  43.898  1.00 30.54  ? 244 THR C O   1 
ATOM   8787  C CB  . THR C 1 244 ? -24.090 14.015  46.861  1.00 30.94  ? 244 THR C CB  1 
ATOM   8788  O OG1 . THR C 1 244 ? -23.129 14.509  47.797  1.00 36.01  ? 244 THR C OG1 1 
ATOM   8789  C CG2 . THR C 1 244 ? -23.399 13.038  45.940  1.00 28.98  ? 244 THR C CG2 1 
ATOM   8790  N N   . ALA C 1 245 ? -26.915 14.111  45.609  1.00 30.57  ? 245 ALA C N   1 
ATOM   8791  C CA  . ALA C 1 245 ? -27.923 13.488  44.767  1.00 34.54  ? 245 ALA C CA  1 
ATOM   8792  C C   . ALA C 1 245 ? -28.355 14.513  43.728  1.00 37.23  ? 245 ALA C C   1 
ATOM   8793  O O   . ALA C 1 245 ? -28.349 14.254  42.526  1.00 42.38  ? 245 ALA C O   1 
ATOM   8794  C CB  . ALA C 1 245 ? -29.084 12.974  45.598  1.00 32.63  ? 245 ALA C CB  1 
ATOM   8795  N N   . HIS C 1 246 ? -28.664 15.710  44.211  1.00 37.69  ? 246 HIS C N   1 
ATOM   8796  C CA  . HIS C 1 246 ? -29.051 16.779  43.316  1.00 41.78  ? 246 HIS C CA  1 
ATOM   8797  C C   . HIS C 1 246 ? -28.004 16.910  42.205  1.00 34.81  ? 246 HIS C C   1 
ATOM   8798  O O   . HIS C 1 246 ? -28.322 16.991  41.025  1.00 32.47  ? 246 HIS C O   1 
ATOM   8799  C CB  . HIS C 1 246 ? -29.252 18.072  44.140  1.00 51.84  ? 246 HIS C CB  1 
ATOM   8800  C CG  . HIS C 1 246 ? -29.458 19.292  43.292  1.00 60.09  ? 246 HIS C CG  1 
ATOM   8801  N ND1 . HIS C 1 246 ? -30.603 19.539  42.583  1.00 54.95  ? 246 HIS C ND1 1 
ATOM   8802  C CD2 . HIS C 1 246 ? -28.573 20.289  42.990  1.00 68.38  ? 246 HIS C CD2 1 
ATOM   8803  C CE1 . HIS C 1 246 ? -30.439 20.643  41.865  1.00 63.01  ? 246 HIS C CE1 1 
ATOM   8804  N NE2 . HIS C 1 246 ? -29.179 21.134  42.108  1.00 61.14  ? 246 HIS C NE2 1 
ATOM   8805  N N   . LEU C 1 247 ? -26.730 16.931  42.596  1.00 38.13  ? 247 LEU C N   1 
ATOM   8806  C CA  . LEU C 1 247 ? -25.639 17.248  41.681  1.00 39.46  ? 247 LEU C CA  1 
ATOM   8807  C C   . LEU C 1 247 ? -25.516 16.128  40.657  1.00 33.74  ? 247 LEU C C   1 
ATOM   8808  O O   . LEU C 1 247 ? -25.531 16.377  39.471  1.00 29.67  ? 247 LEU C O   1 
ATOM   8809  C CB  . LEU C 1 247 ? -24.371 17.474  42.520  1.00 41.75  ? 247 LEU C CB  1 
ATOM   8810  C CG  . LEU C 1 247 ? -23.010 17.311  41.853  1.00 45.63  ? 247 LEU C CG  1 
ATOM   8811  C CD1 . LEU C 1 247 ? -22.877 18.103  40.549  1.00 49.19  ? 247 LEU C CD1 1 
ATOM   8812  C CD2 . LEU C 1 247 ? -21.934 17.722  42.844  1.00 49.37  ? 247 LEU C CD2 1 
ATOM   8813  N N   . VAL C 1 248 ? -25.435 14.888  41.123  1.00 34.38  ? 248 VAL C N   1 
ATOM   8814  C CA  . VAL C 1 248 ? -25.332 13.745  40.231  1.00 32.91  ? 248 VAL C CA  1 
ATOM   8815  C C   . VAL C 1 248 ? -26.543 13.702  39.295  1.00 34.03  ? 248 VAL C C   1 
ATOM   8816  O O   . VAL C 1 248 ? -26.415 13.469  38.087  1.00 35.37  ? 248 VAL C O   1 
ATOM   8817  C CB  . VAL C 1 248 ? -25.192 12.445  41.052  1.00 30.45  ? 248 VAL C CB  1 
ATOM   8818  C CG1 . VAL C 1 248 ? -25.400 11.200  40.203  1.00 30.84  ? 248 VAL C CG1 1 
ATOM   8819  C CG2 . VAL C 1 248 ? -23.860 12.384  41.779  1.00 26.17  ? 248 VAL C CG2 1 
ATOM   8820  N N   . ALA C 1 249 ? -27.733 13.920  39.850  1.00 34.70  ? 249 ALA C N   1 
ATOM   8821  C CA  . ALA C 1 249 ? -28.960 13.812  39.068  1.00 35.87  ? 249 ALA C CA  1 
ATOM   8822  C C   . ALA C 1 249 ? -29.027 14.897  37.979  1.00 33.57  ? 249 ALA C C   1 
ATOM   8823  O O   . ALA C 1 249 ? -29.660 14.694  36.924  1.00 32.70  ? 249 ALA C O   1 
ATOM   8824  C CB  . ALA C 1 249 ? -30.180 13.832  39.981  1.00 35.29  ? 249 ALA C CB  1 
ATOM   8825  N N   . SER C 1 250 ? -28.354 16.034  38.220  1.00 30.09  ? 250 SER C N   1 
ATOM   8826  C CA  . SER C 1 250 ? -28.370 17.144  37.281  1.00 30.20  ? 250 SER C CA  1 
ATOM   8827  C C   . SER C 1 250 ? -27.660 16.798  35.963  1.00 29.65  ? 250 SER C C   1 
ATOM   8828  O O   . SER C 1 250 ? -27.909 17.458  34.948  1.00 34.11  ? 250 SER C O   1 
ATOM   8829  C CB  . SER C 1 250 ? -27.781 18.361  37.923  1.00 32.11  ? 250 SER C CB  1 
ATOM   8830  O OG  . SER C 1 250 ? -26.372 18.254  37.986  1.00 32.95  ? 250 SER C OG  1 
ATOM   8831  N N   . ALA C 1 251 ? -26.829 15.741  35.951  1.00 27.87  ? 251 ALA C N   1 
ATOM   8832  C CA  . ALA C 1 251 ? -26.243 15.202  34.717  1.00 28.14  ? 251 ALA C CA  1 
ATOM   8833  C C   . ALA C 1 251 ? -27.181 14.210  33.999  1.00 28.97  ? 251 ALA C C   1 
ATOM   8834  O O   . ALA C 1 251 ? -26.797 13.634  32.979  1.00 27.35  ? 251 ALA C O   1 
ATOM   8835  C CB  . ALA C 1 251 ? -24.949 14.516  35.075  1.00 26.49  ? 251 ALA C CB  1 
ATOM   8836  N N   . LEU C 1 252 ? -28.381 14.000  34.588  1.00 30.03  ? 252 LEU C N   1 
ATOM   8837  C CA  . LEU C 1 252 ? -29.406 13.049  34.169  1.00 32.41  ? 252 LEU C CA  1 
ATOM   8838  C C   . LEU C 1 252 ? -29.023 11.615  34.518  1.00 34.09  ? 252 LEU C C   1 
ATOM   8839  O O   . LEU C 1 252 ? -29.488 10.699  33.857  1.00 34.34  ? 252 LEU C O   1 
ATOM   8840  C CB  . LEU C 1 252 ? -29.706 13.180  32.670  1.00 33.29  ? 252 LEU C CB  1 
ATOM   8841  C CG  . LEU C 1 252 ? -30.323 14.510  32.231  1.00 34.11  ? 252 LEU C CG  1 
ATOM   8842  C CD1 . LEU C 1 252 ? -30.620 14.483  30.740  1.00 36.15  ? 252 LEU C CD1 1 
ATOM   8843  C CD2 . LEU C 1 252 ? -31.597 14.839  33.006  1.00 30.75  ? 252 LEU C CD2 1 
ATOM   8844  N N   . SER C 1 253 ? -28.195 11.427  35.553  1.00 32.71  ? 253 SER C N   1 
ATOM   8845  C CA  . SER C 1 253 ? -28.067 10.125  36.180  1.00 35.23  ? 253 SER C CA  1 
ATOM   8846  C C   . SER C 1 253 ? -29.385 9.821   36.894  1.00 38.63  ? 253 SER C C   1 
ATOM   8847  O O   . SER C 1 253 ? -30.013 10.723  37.445  1.00 37.25  ? 253 SER C O   1 
ATOM   8848  C CB  . SER C 1 253 ? -26.874 10.056  37.121  1.00 34.59  ? 253 SER C CB  1 
ATOM   8849  O OG  . SER C 1 253 ? -25.638 10.048  36.390  1.00 29.95  ? 253 SER C OG  1 
ATOM   8850  N N   . ASP C 1 254 ? -29.829 8.558   36.844  1.00 36.14  ? 254 ASP C N   1 
ATOM   8851  C CA  . ASP C 1 254 ? -31.068 8.157   37.503  1.00 35.81  ? 254 ASP C CA  1 
ATOM   8852  C C   . ASP C 1 254 ? -30.926 8.207   39.027  1.00 34.37  ? 254 ASP C C   1 
ATOM   8853  O O   . ASP C 1 254 ? -29.842 8.417   39.562  1.00 34.92  ? 254 ASP C O   1 
ATOM   8854  C CB  . ASP C 1 254 ? -31.491 6.764   37.037  1.00 36.43  ? 254 ASP C CB  1 
ATOM   8855  C CG  . ASP C 1 254 ? -30.389 5.735   37.218  1.00 43.12  ? 254 ASP C CG  1 
ATOM   8856  O OD1 . ASP C 1 254 ? -30.005 5.510   38.381  1.00 50.87  ? 254 ASP C OD1 1 
ATOM   8857  O OD2 . ASP C 1 254 ? -29.861 5.236   36.195  1.00 44.78  ? 254 ASP C OD2 1 
ATOM   8858  N N   . ALA C 1 255 ? -32.039 7.966   39.726  1.00 32.90  ? 255 ALA C N   1 
ATOM   8859  C CA  . ALA C 1 255 ? -32.120 8.089   41.172  1.00 32.77  ? 255 ALA C CA  1 
ATOM   8860  C C   . ALA C 1 255 ? -31.315 7.020   41.885  1.00 33.56  ? 255 ALA C C   1 
ATOM   8861  O O   . ALA C 1 255 ? -30.960 7.201   43.055  1.00 37.67  ? 255 ALA C O   1 
ATOM   8862  C CB  . ALA C 1 255 ? -33.550 8.021   41.640  1.00 34.64  ? 255 ALA C CB  1 
ATOM   8863  N N   . TYR C 1 256 ? -31.077 5.899   41.204  1.00 32.51  ? 256 TYR C N   1 
ATOM   8864  C CA  . TYR C 1 256 ? -30.250 4.851   41.789  1.00 32.77  ? 256 TYR C CA  1 
ATOM   8865  C C   . TYR C 1 256 ? -28.807 5.337   41.914  1.00 33.51  ? 256 TYR C C   1 
ATOM   8866  O O   . TYR C 1 256 ? -28.219 5.259   42.984  1.00 36.05  ? 256 TYR C O   1 
ATOM   8867  C CB  . TYR C 1 256 ? -30.415 3.587   40.962  1.00 31.92  ? 256 TYR C CB  1 
ATOM   8868  C CG  . TYR C 1 256 ? -31.797 2.996   41.065  1.00 31.71  ? 256 TYR C CG  1 
ATOM   8869  C CD1 . TYR C 1 256 ? -32.165 2.294   42.193  1.00 32.07  ? 256 TYR C CD1 1 
ATOM   8870  C CD2 . TYR C 1 256 ? -32.745 3.167   40.071  1.00 34.21  ? 256 TYR C CD2 1 
ATOM   8871  C CE1 . TYR C 1 256 ? -33.415 1.728   42.319  1.00 35.49  ? 256 TYR C CE1 1 
ATOM   8872  C CE2 . TYR C 1 256 ? -33.997 2.577   40.165  1.00 36.27  ? 256 TYR C CE2 1 
ATOM   8873  C CZ  . TYR C 1 256 ? -34.344 1.865   41.300  1.00 37.05  ? 256 TYR C CZ  1 
ATOM   8874  O OH  . TYR C 1 256 ? -35.599 1.316   41.465  1.00 32.58  ? 256 TYR C OH  1 
ATOM   8875  N N   . TYR C 1 257 ? -28.267 5.894   40.827  1.00 32.78  ? 257 TYR C N   1 
ATOM   8876  C CA  . TYR C 1 257 ? -26.943 6.504   40.827  1.00 29.56  ? 257 TYR C CA  1 
ATOM   8877  C C   . TYR C 1 257 ? -26.887 7.677   41.808  1.00 28.21  ? 257 TYR C C   1 
ATOM   8878  O O   . TYR C 1 257 ? -25.977 7.791   42.633  1.00 24.68  ? 257 TYR C O   1 
ATOM   8879  C CB  . TYR C 1 257 ? -26.588 6.975   39.414  1.00 28.75  ? 257 TYR C CB  1 
ATOM   8880  C CG  . TYR C 1 257 ? -26.100 5.955   38.407  1.00 28.05  ? 257 TYR C CG  1 
ATOM   8881  C CD1 . TYR C 1 257 ? -25.096 5.045   38.704  1.00 29.86  ? 257 TYR C CD1 1 
ATOM   8882  C CD2 . TYR C 1 257 ? -26.547 5.991   37.099  1.00 27.59  ? 257 TYR C CD2 1 
ATOM   8883  C CE1 . TYR C 1 257 ? -24.559 4.201   37.737  1.00 29.55  ? 257 TYR C CE1 1 
ATOM   8884  C CE2 . TYR C 1 257 ? -26.047 5.140   36.128  1.00 30.59  ? 257 TYR C CE2 1 
ATOM   8885  C CZ  . TYR C 1 257 ? -25.042 4.235   36.440  1.00 32.59  ? 257 TYR C CZ  1 
ATOM   8886  O OH  . TYR C 1 257 ? -24.535 3.384   35.446  1.00 35.97  ? 257 TYR C OH  1 
ATOM   8887  N N   . ALA C 1 258 ? -27.890 8.555   41.731  1.00 30.90  ? 258 ALA C N   1 
ATOM   8888  C CA  . ALA C 1 258 ? -27.935 9.747   42.567  1.00 30.57  ? 258 ALA C CA  1 
ATOM   8889  C C   . ALA C 1 258 ? -27.958 9.419   44.058  1.00 29.50  ? 258 ALA C C   1 
ATOM   8890  O O   . ALA C 1 258 ? -27.289 10.093  44.848  1.00 36.21  ? 258 ALA C O   1 
ATOM   8891  C CB  . ALA C 1 258 ? -29.163 10.551  42.227  1.00 30.73  ? 258 ALA C CB  1 
ATOM   8892  N N   . TYR C 1 259 ? -28.817 8.473   44.448  1.00 26.25  ? 259 TYR C N   1 
ATOM   8893  C CA  . TYR C 1 259 ? -29.006 8.168   45.850  1.00 25.90  ? 259 TYR C CA  1 
ATOM   8894  C C   . TYR C 1 259 ? -27.869 7.270   46.350  1.00 28.11  ? 259 TYR C C   1 
ATOM   8895  O O   . TYR C 1 259 ? -27.456 7.360   47.499  1.00 28.77  ? 259 TYR C O   1 
ATOM   8896  C CB  . TYR C 1 259 ? -30.397 7.583   46.134  1.00 27.88  ? 259 TYR C CB  1 
ATOM   8897  C CG  . TYR C 1 259 ? -30.763 7.813   47.578  1.00 29.52  ? 259 TYR C CG  1 
ATOM   8898  C CD1 . TYR C 1 259 ? -30.837 9.115   48.041  1.00 33.85  ? 259 TYR C CD1 1 
ATOM   8899  C CD2 . TYR C 1 259 ? -30.844 6.796   48.506  1.00 29.50  ? 259 TYR C CD2 1 
ATOM   8900  C CE1 . TYR C 1 259 ? -31.064 9.404   49.379  1.00 36.59  ? 259 TYR C CE1 1 
ATOM   8901  C CE2 . TYR C 1 259 ? -31.097 7.061   49.844  1.00 32.99  ? 259 TYR C CE2 1 
ATOM   8902  C CZ  . TYR C 1 259 ? -31.196 8.370   50.286  1.00 35.15  ? 259 TYR C CZ  1 
ATOM   8903  O OH  . TYR C 1 259 ? -31.458 8.746   51.585  1.00 33.96  ? 259 TYR C OH  1 
ATOM   8904  N N   . SER C 1 260 ? -27.324 6.408   45.498  1.00 31.65  ? 260 SER C N   1 
ATOM   8905  C CA  . SER C 1 260 ? -26.089 5.711   45.833  1.00 35.23  ? 260 SER C CA  1 
ATOM   8906  C C   . SER C 1 260 ? -24.976 6.708   46.164  1.00 35.59  ? 260 SER C C   1 
ATOM   8907  O O   . SER C 1 260 ? -24.313 6.572   47.191  1.00 35.57  ? 260 SER C O   1 
ATOM   8908  C CB  . SER C 1 260 ? -25.688 4.801   44.707  1.00 41.75  ? 260 SER C CB  1 
ATOM   8909  O OG  . SER C 1 260 ? -24.438 4.214   44.980  1.00 52.67  ? 260 SER C OG  1 
ATOM   8910  N N   . ALA C 1 261 ? -24.749 7.696   45.278  1.00 35.69  ? 261 ALA C N   1 
ATOM   8911  C CA  . ALA C 1 261 ? -23.755 8.739   45.500  1.00 34.52  ? 261 ALA C CA  1 
ATOM   8912  C C   . ALA C 1 261 ? -24.001 9.516   46.798  1.00 35.02  ? 261 ALA C C   1 
ATOM   8913  O O   . ALA C 1 261 ? -23.065 9.847   47.526  1.00 36.95  ? 261 ALA C O   1 
ATOM   8914  C CB  . ALA C 1 261 ? -23.777 9.663   44.335  1.00 34.68  ? 261 ALA C CB  1 
ATOM   8915  N N   . ALA C 1 262 ? -25.266 9.839   47.072  1.00 33.86  ? 262 ALA C N   1 
ATOM   8916  C CA  . ALA C 1 262 ? -25.653 10.543  48.286  1.00 35.77  ? 262 ALA C CA  1 
ATOM   8917  C C   . ALA C 1 262 ? -25.273 9.775   49.555  1.00 31.18  ? 262 ALA C C   1 
ATOM   8918  O O   . ALA C 1 262 ? -24.841 10.373  50.533  1.00 35.26  ? 262 ALA C O   1 
ATOM   8919  C CB  . ALA C 1 262 ? -27.129 10.829  48.250  1.00 33.82  ? 262 ALA C CB  1 
ATOM   8920  N N   . MET C 1 263 ? -25.458 8.465   49.542  1.00 31.55  ? 263 MET C N   1 
ATOM   8921  C CA  . MET C 1 263 ? -25.109 7.597   50.668  1.00 34.25  ? 263 MET C CA  1 
ATOM   8922  C C   . MET C 1 263 ? -23.591 7.533   50.878  1.00 31.39  ? 263 MET C C   1 
ATOM   8923  O O   . MET C 1 263 ? -23.113 7.429   52.018  1.00 23.55  ? 263 MET C O   1 
ATOM   8924  C CB  . MET C 1 263 ? -25.678 6.186   50.448  1.00 30.85  ? 263 MET C CB  1 
ATOM   8925  C CG  . MET C 1 263 ? -27.202 6.155   50.488  1.00 33.37  ? 263 MET C CG  1 
ATOM   8926  S SD  . MET C 1 263 ? -27.940 6.913   52.016  1.00 35.05  ? 263 MET C SD  1 
ATOM   8927  C CE  . MET C 1 263 ? -28.026 8.628   51.512  1.00 41.53  ? 263 MET C CE  1 
ATOM   8928  N N   . CYS C 1 264 ? -22.830 7.616   49.777  1.00 33.97  ? 264 CYS C N   1 
ATOM   8929  C CA  . CYS C 1 264 ? -21.389 7.806   49.896  1.00 37.34  ? 264 CYS C CA  1 
ATOM   8930  C C   . CYS C 1 264 ? -21.068 9.086   50.688  1.00 37.02  ? 264 CYS C C   1 
ATOM   8931  O O   . CYS C 1 264 ? -20.148 9.076   51.516  1.00 32.94  ? 264 CYS C O   1 
ATOM   8932  C CB  . CYS C 1 264 ? -20.725 7.838   48.527  1.00 37.60  ? 264 CYS C CB  1 
ATOM   8933  S SG  . CYS C 1 264 ? -20.824 6.245   47.682  1.00 42.93  ? 264 CYS C SG  1 
ATOM   8934  N N   . GLY C 1 265 ? -21.840 10.167  50.444  1.00 32.31  ? 265 GLY C N   1 
ATOM   8935  C CA  . GLY C 1 265 ? -21.700 11.410  51.183  1.00 30.81  ? 265 GLY C CA  1 
ATOM   8936  C C   . GLY C 1 265 ? -22.156 11.299  52.639  1.00 30.99  ? 265 GLY C C   1 
ATOM   8937  O O   . GLY C 1 265 ? -21.460 11.781  53.556  1.00 29.51  ? 265 GLY C O   1 
ATOM   8938  N N   . LEU C 1 266 ? -23.323 10.665  52.850  1.00 29.36  ? 266 LEU C N   1 
ATOM   8939  C CA  . LEU C 1 266 ? -23.873 10.512  54.187  1.00 29.74  ? 266 LEU C CA  1 
ATOM   8940  C C   . LEU C 1 266 ? -22.944 9.701   55.079  1.00 29.49  ? 266 LEU C C   1 
ATOM   8941  O O   . LEU C 1 266 ? -22.992 9.845   56.288  1.00 32.41  ? 266 LEU C O   1 
ATOM   8942  C CB  . LEU C 1 266 ? -25.243 9.849   54.099  1.00 33.16  ? 266 LEU C CB  1 
ATOM   8943  C CG  . LEU C 1 266 ? -26.003 9.780   55.428  1.00 40.14  ? 266 LEU C CG  1 
ATOM   8944  C CD1 . LEU C 1 266 ? -26.318 11.164  55.978  1.00 38.02  ? 266 LEU C CD1 1 
ATOM   8945  C CD2 . LEU C 1 266 ? -27.298 8.988   55.292  1.00 41.83  ? 266 LEU C CD2 1 
ATOM   8946  N N   . ALA C 1 267 ? -22.114 8.826   54.505  1.00 34.62  ? 267 ALA C N   1 
ATOM   8947  C CA  . ALA C 1 267 ? -21.247 7.958   55.300  1.00 38.17  ? 267 ALA C CA  1 
ATOM   8948  C C   . ALA C 1 267 ? -20.066 8.725   55.897  1.00 35.91  ? 267 ALA C C   1 
ATOM   8949  O O   . ALA C 1 267 ? -19.380 8.209   56.768  1.00 35.99  ? 267 ALA C O   1 
ATOM   8950  C CB  . ALA C 1 267 ? -20.762 6.801   54.452  1.00 36.96  ? 267 ALA C CB  1 
ATOM   8951  N N   . GLY C 1 268 ? -19.812 9.937   55.396  1.00 39.67  ? 268 GLY C N   1 
ATOM   8952  C CA  . GLY C 1 268 ? -18.777 10.808  55.931  1.00 41.41  ? 268 GLY C CA  1 
ATOM   8953  C C   . GLY C 1 268 ? -18.917 11.036  57.434  1.00 40.14  ? 268 GLY C C   1 
ATOM   8954  O O   . GLY C 1 268 ? -20.018 11.260  57.940  1.00 46.57  ? 268 GLY C O   1 
ATOM   8955  N N   . PRO C 1 269 ? -17.804 11.015  58.197  1.00 38.18  ? 269 PRO C N   1 
ATOM   8956  C CA  . PRO C 1 269 ? -17.872 11.275  59.638  1.00 38.98  ? 269 PRO C CA  1 
ATOM   8957  C C   . PRO C 1 269 ? -18.449 12.637  60.010  1.00 37.80  ? 269 PRO C C   1 
ATOM   8958  O O   . PRO C 1 269 ? -19.063 12.787  61.062  1.00 43.52  ? 269 PRO C O   1 
ATOM   8959  C CB  . PRO C 1 269 ? -16.412 11.178  60.103  1.00 40.62  ? 269 PRO C CB  1 
ATOM   8960  C CG  . PRO C 1 269 ? -15.669 10.448  58.982  1.00 37.25  ? 269 PRO C CG  1 
ATOM   8961  C CD  . PRO C 1 269 ? -16.444 10.739  57.718  1.00 35.76  ? 269 PRO C CD  1 
ATOM   8962  N N   . LEU C 1 270 ? -18.247 13.630  59.137  1.00 38.94  ? 270 LEU C N   1 
ATOM   8963  C CA  . LEU C 1 270 ? -18.756 14.971  59.379  1.00 42.34  ? 270 LEU C CA  1 
ATOM   8964  C C   . LEU C 1 270 ? -20.230 15.105  59.002  1.00 43.67  ? 270 LEU C C   1 
ATOM   8965  O O   . LEU C 1 270 ? -20.774 16.191  59.121  1.00 45.72  ? 270 LEU C O   1 
ATOM   8966  C CB  . LEU C 1 270 ? -17.920 15.967  58.565  1.00 38.35  ? 270 LEU C CB  1 
ATOM   8967  C CG  . LEU C 1 270 ? -16.486 16.103  59.040  1.00 36.26  ? 270 LEU C CG  1 
ATOM   8968  C CD1 . LEU C 1 270 ? -15.811 17.288  58.374  1.00 38.58  ? 270 LEU C CD1 1 
ATOM   8969  C CD2 . LEU C 1 270 ? -16.441 16.218  60.552  1.00 34.82  ? 270 LEU C CD2 1 
ATOM   8970  N N   . HIS C 1 271 ? -20.866 14.027  58.539  1.00 42.67  ? 271 HIS C N   1 
ATOM   8971  C CA  . HIS C 1 271 ? -22.257 14.097  58.151  1.00 43.44  ? 271 HIS C CA  1 
ATOM   8972  C C   . HIS C 1 271 ? -23.086 13.035  58.899  1.00 48.90  ? 271 HIS C C   1 
ATOM   8973  O O   . HIS C 1 271 ? -23.915 13.366  59.760  1.00 44.78  ? 271 HIS C O   1 
ATOM   8974  C CB  . HIS C 1 271 ? -22.322 14.017  56.626  1.00 42.89  ? 271 HIS C CB  1 
ATOM   8975  C CG  . HIS C 1 271 ? -23.643 14.428  56.051  1.00 46.11  ? 271 HIS C CG  1 
ATOM   8976  N ND1 . HIS C 1 271 ? -24.638 15.010  56.804  1.00 50.85  ? 271 HIS C ND1 1 
ATOM   8977  C CD2 . HIS C 1 271 ? -24.126 14.294  54.780  1.00 43.46  ? 271 HIS C CD2 1 
ATOM   8978  C CE1 . HIS C 1 271 ? -25.693 15.240  56.029  1.00 48.36  ? 271 HIS C CE1 1 
ATOM   8979  N NE2 . HIS C 1 271 ? -25.389 14.820  54.763  1.00 47.30  ? 271 HIS C NE2 1 
ATOM   8980  N N   . GLY C 1 272 ? -22.826 11.749  58.619  1.00 55.12  ? 272 GLY C N   1 
ATOM   8981  C CA  . GLY C 1 272 ? -23.742 10.688  59.009  1.00 52.10  ? 272 GLY C CA  1 
ATOM   8982  C C   . GLY C 1 272 ? -23.351 9.963   60.288  1.00 52.55  ? 272 GLY C C   1 
ATOM   8983  O O   . GLY C 1 272 ? -24.138 9.154   60.766  1.00 57.77  ? 272 GLY C O   1 
ATOM   8984  N N   . LEU C 1 273 ? -22.165 10.263  60.845  1.00 59.95  ? 273 LEU C N   1 
ATOM   8985  C CA  . LEU C 1 273 ? -21.637 9.499   61.971  1.00 62.73  ? 273 LEU C CA  1 
ATOM   8986  C C   . LEU C 1 273 ? -21.777 10.270  63.282  1.00 62.18  ? 273 LEU C C   1 
ATOM   8987  O O   . LEU C 1 273 ? -21.321 9.794   64.315  1.00 57.94  ? 273 LEU C O   1 
ATOM   8988  C CB  . LEU C 1 273 ? -20.171 9.134   61.710  1.00 66.77  ? 273 LEU C CB  1 
ATOM   8989  C CG  . LEU C 1 273 ? -19.913 7.800   60.998  1.00 68.70  ? 273 LEU C CG  1 
ATOM   8990  C CD1 . LEU C 1 273 ? -20.736 7.650   59.722  1.00 69.07  ? 273 LEU C CD1 1 
ATOM   8991  C CD2 . LEU C 1 273 ? -18.431 7.636   60.661  1.00 65.86  ? 273 LEU C CD2 1 
ATOM   8992  N N   . ALA C 1 274 ? -22.452 11.425  63.252  1.00 63.41  ? 274 ALA C N   1 
ATOM   8993  C CA  . ALA C 1 274 ? -22.577 12.288  64.417  1.00 67.83  ? 274 ALA C CA  1 
ATOM   8994  C C   . ALA C 1 274 ? -23.383 11.625  65.542  1.00 65.61  ? 274 ALA C C   1 
ATOM   8995  O O   . ALA C 1 274 ? -23.118 11.864  66.720  1.00 59.86  ? 274 ALA C O   1 
ATOM   8996  C CB  . ALA C 1 274 ? -23.191 13.594  63.977  1.00 68.68  ? 274 ALA C CB  1 
ATOM   8997  N N   . ASN C 1 275 ? -24.336 10.764  65.164  1.00 76.22  ? 275 ASN C N   1 
ATOM   8998  C CA  . ASN C 1 275 ? -25.331 10.181  66.060  1.00 81.74  ? 275 ASN C CA  1 
ATOM   8999  C C   . ASN C 1 275 ? -24.694 9.144   67.002  1.00 76.14  ? 275 ASN C C   1 
ATOM   9000  O O   . ASN C 1 275 ? -24.997 9.137   68.201  1.00 56.54  ? 275 ASN C O   1 
ATOM   9001  C CB  . ASN C 1 275 ? -26.486 9.604   65.221  1.00 81.22  ? 275 ASN C CB  1 
ATOM   9002  C CG  . ASN C 1 275 ? -27.634 9.035   66.035  1.00 90.09  ? 275 ASN C CG  1 
ATOM   9003  O OD1 . ASN C 1 275 ? -27.562 8.941   67.261  1.00 93.01  ? 275 ASN C OD1 1 
ATOM   9004  N ND2 . ASN C 1 275 ? -28.704 8.644   65.360  1.00 94.52  ? 275 ASN C ND2 1 
ATOM   9005  N N   . GLN C 1 276 ? -23.851 8.250   66.444  1.00 74.10  ? 276 GLN C N   1 
ATOM   9006  C CA  . GLN C 1 276 ? -23.139 7.232   67.214  1.00 73.93  ? 276 GLN C CA  1 
ATOM   9007  C C   . GLN C 1 276 ? -22.022 7.866   68.040  1.00 75.63  ? 276 GLN C C   1 
ATOM   9008  O O   . GLN C 1 276 ? -21.818 7.457   69.186  1.00 62.05  ? 276 GLN C O   1 
ATOM   9009  C CB  . GLN C 1 276 ? -22.531 6.103   66.365  1.00 68.07  ? 276 GLN C CB  1 
ATOM   9010  C CG  . GLN C 1 276 ? -21.923 6.516   65.030  1.00 64.18  ? 276 GLN C CG  1 
ATOM   9011  C CD  . GLN C 1 276 ? -22.964 6.452   63.934  1.00 65.64  ? 276 GLN C CD  1 
ATOM   9012  O OE1 . GLN C 1 276 ? -23.996 7.124   63.977  1.00 54.96  ? 276 GLN C OE1 1 
ATOM   9013  N NE2 . GLN C 1 276 ? -22.707 5.618   62.939  1.00 71.39  ? 276 GLN C NE2 1 
ATOM   9014  N N   . GLU C 1 277 ? -21.311 8.847   67.449  1.00 81.70  ? 277 GLU C N   1 
ATOM   9015  C CA  . GLU C 1 277 ? -20.188 9.507   68.105  1.00 73.06  ? 277 GLU C CA  1 
ATOM   9016  C C   . GLU C 1 277 ? -20.676 10.287  69.326  1.00 61.14  ? 277 GLU C C   1 
ATOM   9017  O O   . GLU C 1 277 ? -19.900 10.489  70.261  1.00 63.03  ? 277 GLU C O   1 
ATOM   9018  C CB  . GLU C 1 277 ? -19.395 10.362  67.109  1.00 76.97  ? 277 GLU C CB  1 
ATOM   9019  C CG  . GLU C 1 277 ? -18.615 9.523   66.095  1.00 89.82  ? 277 GLU C CG  1 
ATOM   9020  C CD  . GLU C 1 277 ? -17.606 10.268  65.219  1.00 97.09  ? 277 GLU C CD  1 
ATOM   9021  O OE1 . GLU C 1 277 ? -17.289 11.434  65.537  1.00 87.67  ? 277 GLU C OE1 1 
ATOM   9022  O OE2 . GLU C 1 277 ? -17.112 9.679   64.221  1.00 95.80  ? 277 GLU C OE2 1 
ATOM   9023  N N   . VAL C 1 278 ? -21.968 10.654  69.353  1.00 53.62  ? 278 VAL C N   1 
ATOM   9024  C CA  . VAL C 1 278 ? -22.575 11.273  70.527  1.00 51.87  ? 278 VAL C CA  1 
ATOM   9025  C C   . VAL C 1 278 ? -22.793 10.253  71.635  1.00 52.44  ? 278 VAL C C   1 
ATOM   9026  O O   . VAL C 1 278 ? -22.385 10.492  72.766  1.00 48.83  ? 278 VAL C O   1 
ATOM   9027  C CB  . VAL C 1 278 ? -23.912 11.960  70.196  1.00 49.21  ? 278 VAL C CB  1 
ATOM   9028  C CG1 . VAL C 1 278 ? -24.767 12.195  71.449  1.00 44.65  ? 278 VAL C CG1 1 
ATOM   9029  C CG2 . VAL C 1 278 ? -23.695 13.251  69.424  1.00 47.13  ? 278 VAL C CG2 1 
ATOM   9030  N N   . LEU C 1 279 ? -23.510 9.168   71.302  1.00 61.31  ? 279 LEU C N   1 
ATOM   9031  C CA  . LEU C 1 279 ? -23.920 8.156   72.270  1.00 60.62  ? 279 LEU C CA  1 
ATOM   9032  C C   . LEU C 1 279 ? -22.695 7.502   72.905  1.00 56.45  ? 279 LEU C C   1 
ATOM   9033  O O   . LEU C 1 279 ? -22.645 7.397   74.128  1.00 55.78  ? 279 LEU C O   1 
ATOM   9034  C CB  . LEU C 1 279 ? -24.810 7.123   71.568  1.00 59.34  ? 279 LEU C CB  1 
ATOM   9035  C CG  . LEU C 1 279 ? -25.325 5.984   72.445  1.00 64.99  ? 279 LEU C CG  1 
ATOM   9036  C CD1 . LEU C 1 279 ? -26.183 6.499   73.588  1.00 68.86  ? 279 LEU C CD1 1 
ATOM   9037  C CD2 . LEU C 1 279 ? -26.100 4.971   71.625  1.00 70.71  ? 279 LEU C CD2 1 
ATOM   9038  N N   . LYS C 1 280 ? -21.723 7.081   72.075  1.00 61.86  ? 280 LYS C N   1 
ATOM   9039  C CA  . LYS C 1 280 ? -20.478 6.470   72.537  1.00 68.59  ? 280 LYS C CA  1 
ATOM   9040  C C   . LYS C 1 280 ? -19.835 7.327   73.624  1.00 68.43  ? 280 LYS C C   1 
ATOM   9041  O O   . LYS C 1 280 ? -19.402 6.832   74.664  1.00 76.63  ? 280 LYS C O   1 
ATOM   9042  C CB  . LYS C 1 280 ? -19.467 6.320   71.393  1.00 62.36  ? 280 LYS C CB  1 
ATOM   9043  C CG  . LYS C 1 280 ? -19.675 5.094   70.530  1.00 64.35  ? 280 LYS C CG  1 
ATOM   9044  C CD  . LYS C 1 280 ? -18.702 5.019   69.379  1.00 73.93  ? 280 LYS C CD  1 
ATOM   9045  C CE  . LYS C 1 280 ? -18.850 3.749   68.571  1.00 75.64  ? 280 LYS C CE  1 
ATOM   9046  N NZ  . LYS C 1 280 ? -18.663 4.028   67.131  1.00 77.40  ? 280 LYS C NZ  1 
ATOM   9047  N N   . TRP C 1 281 ? -19.783 8.624   73.338  1.00 66.41  ? 281 TRP C N   1 
ATOM   9048  C CA  . TRP C 1 281 ? -19.175 9.603   74.213  1.00 70.06  ? 281 TRP C CA  1 
ATOM   9049  C C   . TRP C 1 281 ? -20.013 9.778   75.489  1.00 66.62  ? 281 TRP C C   1 
ATOM   9050  O O   . TRP C 1 281 ? -19.444 9.987   76.559  1.00 70.53  ? 281 TRP C O   1 
ATOM   9051  C CB  . TRP C 1 281 ? -18.953 10.885  73.392  1.00 72.59  ? 281 TRP C CB  1 
ATOM   9052  C CG  . TRP C 1 281 ? -18.475 12.065  74.169  1.00 78.68  ? 281 TRP C CG  1 
ATOM   9053  C CD1 . TRP C 1 281 ? -17.194 12.527  74.263  1.00 82.14  ? 281 TRP C CD1 1 
ATOM   9054  C CD2 . TRP C 1 281 ? -19.293 12.970  74.931  1.00 80.54  ? 281 TRP C CD2 1 
ATOM   9055  N NE1 . TRP C 1 281 ? -17.158 13.646  75.056  1.00 79.17  ? 281 TRP C NE1 1 
ATOM   9056  C CE2 . TRP C 1 281 ? -18.428 13.936  75.486  1.00 75.31  ? 281 TRP C CE2 1 
ATOM   9057  C CE3 . TRP C 1 281 ? -20.664 13.054  75.204  1.00 80.37  ? 281 TRP C CE3 1 
ATOM   9058  C CZ2 . TRP C 1 281 ? -18.902 14.977  76.284  1.00 83.33  ? 281 TRP C CZ2 1 
ATOM   9059  C CZ3 . TRP C 1 281 ? -21.128 14.068  76.012  1.00 74.25  ? 281 TRP C CZ3 1 
ATOM   9060  C CH2 . TRP C 1 281 ? -20.257 15.019  76.538  1.00 83.52  ? 281 TRP C CH2 1 
ATOM   9061  N N   . ILE C 1 282 ? -21.351 9.654   75.416  1.00 62.44  ? 282 ILE C N   1 
ATOM   9062  C CA  . ILE C 1 282 ? -22.186 9.714   76.614  1.00 60.50  ? 282 ILE C CA  1 
ATOM   9063  C C   . ILE C 1 282 ? -21.938 8.466   77.458  1.00 60.17  ? 282 ILE C C   1 
ATOM   9064  O O   . ILE C 1 282 ? -21.828 8.564   78.675  1.00 63.06  ? 282 ILE C O   1 
ATOM   9065  C CB  . ILE C 1 282 ? -23.687 9.890   76.294  1.00 58.56  ? 282 ILE C CB  1 
ATOM   9066  C CG1 . ILE C 1 282 ? -23.988 11.269  75.701  1.00 61.64  ? 282 ILE C CG1 1 
ATOM   9067  C CG2 . ILE C 1 282 ? -24.546 9.624   77.529  1.00 61.87  ? 282 ILE C CG2 1 
ATOM   9068  C CD1 . ILE C 1 282 ? -25.460 11.566  75.496  1.00 64.19  ? 282 ILE C CD1 1 
ATOM   9069  N N   . GLN C 1 283 ? -21.847 7.303   76.800  1.00 61.33  ? 283 GLN C N   1 
ATOM   9070  C CA  . GLN C 1 283 ? -21.657 6.026   77.472  1.00 65.55  ? 283 GLN C CA  1 
ATOM   9071  C C   . GLN C 1 283 ? -20.267 5.908   78.107  1.00 76.52  ? 283 GLN C C   1 
ATOM   9072  O O   . GLN C 1 283 ? -20.130 5.317   79.183  1.00 79.30  ? 283 GLN C O   1 
ATOM   9073  C CB  . GLN C 1 283 ? -21.866 4.891   76.470  1.00 59.72  ? 283 GLN C CB  1 
ATOM   9074  C CG  . GLN C 1 283 ? -23.303 4.750   75.990  1.00 59.65  ? 283 GLN C CG  1 
ATOM   9075  C CD  . GLN C 1 283 ? -23.442 3.572   75.061  1.00 56.52  ? 283 GLN C CD  1 
ATOM   9076  O OE1 . GLN C 1 283 ? -24.226 2.659   75.302  1.00 58.29  ? 283 GLN C OE1 1 
ATOM   9077  N NE2 . GLN C 1 283 ? -22.646 3.578   74.005  1.00 54.23  ? 283 GLN C NE2 1 
ATOM   9078  N N   . GLU C 1 284 ? -19.241 6.419   77.405  1.00 81.19  ? 284 GLU C N   1 
ATOM   9079  C CA  . GLU C 1 284 ? -17.875 6.507   77.906  1.00 81.23  ? 284 GLU C CA  1 
ATOM   9080  C C   . GLU C 1 284 ? -17.813 7.414   79.140  1.00 73.23  ? 284 GLU C C   1 
ATOM   9081  O O   . GLU C 1 284 ? -17.053 7.133   80.054  1.00 83.31  ? 284 GLU C O   1 
ATOM   9082  C CB  . GLU C 1 284 ? -16.975 6.999   76.768  1.00 83.43  ? 284 GLU C CB  1 
ATOM   9083  C CG  . GLU C 1 284 ? -15.635 7.569   77.202  1.00 100.43 ? 284 GLU C CG  1 
ATOM   9084  C CD  . GLU C 1 284 ? -15.323 8.918   76.566  1.00 109.55 ? 284 GLU C CD  1 
ATOM   9085  O OE1 . GLU C 1 284 ? -15.209 8.977   75.322  1.00 118.05 ? 284 GLU C OE1 1 
ATOM   9086  O OE2 . GLU C 1 284 ? -15.215 9.917   77.314  1.00 111.31 ? 284 GLU C OE2 1 
ATOM   9087  N N   . THR C 1 285 ? -18.632 8.471   79.170  1.00 75.25  ? 285 THR C N   1 
ATOM   9088  C CA  . THR C 1 285 ? -18.646 9.474   80.233  1.00 89.16  ? 285 THR C CA  1 
ATOM   9089  C C   . THR C 1 285 ? -19.363 8.967   81.495  1.00 84.66  ? 285 THR C C   1 
ATOM   9090  O O   . THR C 1 285 ? -18.845 9.134   82.591  1.00 82.32  ? 285 THR C O   1 
ATOM   9091  C CB  . THR C 1 285 ? -19.258 10.788  79.707  1.00 93.24  ? 285 THR C CB  1 
ATOM   9092  O OG1 . THR C 1 285 ? -18.296 11.446  78.879  1.00 87.72  ? 285 THR C OG1 1 
ATOM   9093  C CG2 . THR C 1 285 ? -19.713 11.732  80.799  1.00 85.65  ? 285 THR C CG2 1 
ATOM   9094  N N   . ILE C 1 286 ? -20.567 8.387   81.352  1.00 80.89  ? 286 ILE C N   1 
ATOM   9095  C CA  . ILE C 1 286 ? -21.283 7.749   82.452  1.00 78.70  ? 286 ILE C CA  1 
ATOM   9096  C C   . ILE C 1 286 ? -20.409 6.690   83.124  1.00 82.53  ? 286 ILE C C   1 
ATOM   9097  O O   . ILE C 1 286 ? -20.541 6.471   84.322  1.00 96.15  ? 286 ILE C O   1 
ATOM   9098  C CB  . ILE C 1 286 ? -22.584 7.081   81.962  1.00 80.21  ? 286 ILE C CB  1 
ATOM   9099  C CG1 . ILE C 1 286 ? -23.615 8.095   81.457  1.00 79.49  ? 286 ILE C CG1 1 
ATOM   9100  C CG2 . ILE C 1 286 ? -23.165 6.168   83.041  1.00 75.97  ? 286 ILE C CG2 1 
ATOM   9101  C CD1 . ILE C 1 286 ? -24.813 7.462   80.766  1.00 81.77  ? 286 ILE C CD1 1 
ATOM   9102  N N   . ASP C 1 287 ? -19.588 5.986   82.334  1.00 86.93  ? 287 ASP C N   1 
ATOM   9103  C CA  . ASP C 1 287 ? -18.776 4.878   82.814  1.00 88.11  ? 287 ASP C CA  1 
ATOM   9104  C C   . ASP C 1 287 ? -17.518 5.377   83.535  1.00 93.41  ? 287 ASP C C   1 
ATOM   9105  O O   . ASP C 1 287 ? -17.231 4.937   84.648  1.00 91.61  ? 287 ASP C O   1 
ATOM   9106  C CB  . ASP C 1 287 ? -18.378 3.968   81.652  1.00 88.94  ? 287 ASP C CB  1 
ATOM   9107  C CG  . ASP C 1 287 ? -17.588 2.753   82.092  1.00 88.78  ? 287 ASP C CG  1 
ATOM   9108  O OD1 . ASP C 1 287 ? -18.201 1.877   82.751  1.00 81.50  ? 287 ASP C OD1 1 
ATOM   9109  O OD2 . ASP C 1 287 ? -16.366 2.709   81.789  1.00 89.12  ? 287 ASP C OD2 1 
ATOM   9110  N N   . LYS C 1 288 ? -16.841 6.349   82.940  1.00 95.12  ? 288 LYS C N   1 
ATOM   9111  C CA  . LYS C 1 288 ? -15.548 6.795   83.503  1.00 95.62  ? 288 LYS C CA  1 
ATOM   9112  C C   . LYS C 1 288 ? -15.673 7.928   84.524  1.00 101.44 ? 288 LYS C C   1 
ATOM   9113  O O   . LYS C 1 288 ? -15.393 7.671   85.703  1.00 101.09 ? 288 LYS C O   1 
ATOM   9114  C CB  . LYS C 1 288 ? -14.674 7.266   82.340  1.00 97.43  ? 288 LYS C CB  1 
ATOM   9115  C CG  . LYS C 1 288 ? -13.641 6.262   81.853  1.00 99.28  ? 288 LYS C CG  1 
ATOM   9116  C CD  . LYS C 1 288 ? -13.709 6.023   80.365  1.00 93.58  ? 288 LYS C CD  1 
ATOM   9117  C CE  . LYS C 1 288 ? -14.215 4.641   80.018  1.00 96.12  ? 288 LYS C CE  1 
ATOM   9118  N NZ  . LYS C 1 288 ? -13.943 3.674   81.107  1.00 98.79  ? 288 LYS C NZ  1 
ATOM   9119  N N   . LYS C 1 289 ? -16.119 9.115   84.122  1.00 103.59 ? 289 LYS C N   1 
ATOM   9120  C CA  . LYS C 1 289 ? -16.052 10.285  84.987  1.00 108.57 ? 289 LYS C CA  1 
ATOM   9121  C C   . LYS C 1 289 ? -17.088 10.258  86.118  1.00 108.73 ? 289 LYS C C   1 
ATOM   9122  O O   . LYS C 1 289 ? -16.857 10.889  87.149  1.00 115.56 ? 289 LYS C O   1 
ATOM   9123  C CB  . LYS C 1 289 ? -16.234 11.562  84.153  1.00 106.28 ? 289 LYS C CB  1 
ATOM   9124  C CG  . LYS C 1 289 ? -14.957 12.211  83.636  1.00 100.40 ? 289 LYS C CG  1 
ATOM   9125  C CD  . LYS C 1 289 ? -14.167 11.389  82.636  1.00 95.07  ? 289 LYS C CD  1 
ATOM   9126  C CE  . LYS C 1 289 ? -12.967 12.154  82.114  1.00 94.90  ? 289 LYS C CE  1 
ATOM   9127  N NZ  . LYS C 1 289 ? -11.846 11.264  81.731  1.00 91.62  ? 289 LYS C NZ  1 
ATOM   9128  N N   . LEU C 1 290 ? -18.224 9.565   85.929  1.00 99.93  ? 290 LEU C N   1 
ATOM   9129  C CA  . LEU C 1 290 ? -19.358 9.666   86.841  1.00 98.24  ? 290 LEU C CA  1 
ATOM   9130  C C   . LEU C 1 290 ? -19.760 8.291   87.377  1.00 96.08  ? 290 LEU C C   1 
ATOM   9131  O O   . LEU C 1 290 ? -20.866 8.160   87.901  1.00 78.30  ? 290 LEU C O   1 
ATOM   9132  C CB  . LEU C 1 290 ? -20.528 10.311  86.088  1.00 106.93 ? 290 LEU C CB  1 
ATOM   9133  C CG  . LEU C 1 290 ? -20.149 11.400  85.079  1.00 104.52 ? 290 LEU C CG  1 
ATOM   9134  C CD1 . LEU C 1 290 ? -21.313 11.688  84.149  1.00 106.21 ? 290 LEU C CD1 1 
ATOM   9135  C CD2 . LEU C 1 290 ? -19.676 12.678  85.768  1.00 94.98  ? 290 LEU C CD2 1 
ATOM   9136  N N   . GLY C 1 291 ? -18.888 7.280   87.173  1.00 103.03 ? 291 GLY C N   1 
ATOM   9137  C CA  . GLY C 1 291 ? -18.896 6.011   87.898  1.00 98.12  ? 291 GLY C CA  1 
ATOM   9138  C C   . GLY C 1 291 ? -20.095 5.096   87.618  1.00 100.61 ? 291 GLY C C   1 
ATOM   9139  O O   . GLY C 1 291 ? -20.651 4.512   88.550  1.00 97.22  ? 291 GLY C O   1 
ATOM   9140  N N   . GLY C 1 292 ? -20.469 4.940   86.339  1.00 109.14 ? 292 GLY C N   1 
ATOM   9141  C CA  . GLY C 1 292 ? -21.538 4.039   85.920  1.00 104.92 ? 292 GLY C CA  1 
ATOM   9142  C C   . GLY C 1 292 ? -22.905 4.395   86.513  1.00 107.27 ? 292 GLY C C   1 
ATOM   9143  O O   . GLY C 1 292 ? -23.759 3.523   86.663  1.00 87.88  ? 292 GLY C O   1 
ATOM   9144  N N   . LYS C 1 293 ? -23.111 5.682   86.829  1.00 115.43 ? 293 LYS C N   1 
ATOM   9145  C CA  . LYS C 1 293 ? -24.337 6.148   87.463  1.00 114.07 ? 293 LYS C CA  1 
ATOM   9146  C C   . LYS C 1 293 ? -24.644 7.549   86.926  1.00 116.02 ? 293 LYS C C   1 
ATOM   9147  O O   . LYS C 1 293 ? -23.727 8.305   86.580  1.00 98.64  ? 293 LYS C O   1 
ATOM   9148  C CB  . LYS C 1 293 ? -24.207 5.976   88.989  1.00 107.90 ? 293 LYS C CB  1 
ATOM   9149  C CG  . LYS C 1 293 ? -24.919 6.954   89.928  1.00 109.14 ? 293 LYS C CG  1 
ATOM   9150  C CD  . LYS C 1 293 ? -26.395 7.313   89.672  1.00 118.53 ? 293 LYS C CD  1 
ATOM   9151  C CE  . LYS C 1 293 ? -27.291 6.207   89.148  1.00 118.12 ? 293 LYS C CE  1 
ATOM   9152  N NZ  . LYS C 1 293 ? -27.471 5.128   90.140  1.00 129.54 ? 293 LYS C NZ  1 
ATOM   9153  N N   . VAL C 1 294 ? -25.954 7.812   86.760  1.00 115.39 ? 294 VAL C N   1 
ATOM   9154  C CA  . VAL C 1 294 ? -26.502 9.119   86.419  1.00 110.73 ? 294 VAL C CA  1 
ATOM   9155  C C   . VAL C 1 294 ? -25.923 10.160  87.373  1.00 109.68 ? 294 VAL C C   1 
ATOM   9156  O O   . VAL C 1 294 ? -26.211 10.128  88.568  1.00 108.75 ? 294 VAL C O   1 
ATOM   9157  C CB  . VAL C 1 294 ? -28.045 9.154   86.506  1.00 97.90  ? 294 VAL C CB  1 
ATOM   9158  C CG1 . VAL C 1 294 ? -28.602 10.433  85.898  1.00 89.83  ? 294 VAL C CG1 1 
ATOM   9159  C CG2 . VAL C 1 294 ? -28.706 7.926   85.891  1.00 96.60  ? 294 VAL C CG2 1 
ATOM   9160  N N   . PRO C 1 295 ? -25.134 11.145  86.891  1.00 116.53 ? 295 PRO C N   1 
ATOM   9161  C CA  . PRO C 1 295 ? -24.579 12.161  87.784  1.00 119.35 ? 295 PRO C CA  1 
ATOM   9162  C C   . PRO C 1 295 ? -25.694 13.040  88.355  1.00 123.31 ? 295 PRO C C   1 
ATOM   9163  O O   . PRO C 1 295 ? -26.832 13.001  87.889  1.00 102.29 ? 295 PRO C O   1 
ATOM   9164  C CB  . PRO C 1 295 ? -23.616 12.936  86.868  1.00 113.85 ? 295 PRO C CB  1 
ATOM   9165  C CG  . PRO C 1 295 ? -24.252 12.798  85.507  1.00 107.76 ? 295 PRO C CG  1 
ATOM   9166  C CD  . PRO C 1 295 ? -24.775 11.378  85.482  1.00 112.51 ? 295 PRO C CD  1 
ATOM   9167  N N   . THR C 1 296 ? -25.362 13.796  89.405  1.00 132.32 ? 296 THR C N   1 
ATOM   9168  C CA  . THR C 1 296 ? -26.161 14.943  89.805  1.00 128.92 ? 296 THR C CA  1 
ATOM   9169  C C   . THR C 1 296 ? -25.851 16.077  88.825  1.00 126.48 ? 296 THR C C   1 
ATOM   9170  O O   . THR C 1 296 ? -24.852 16.038  88.100  1.00 107.25 ? 296 THR C O   1 
ATOM   9171  C CB  . THR C 1 296 ? -25.916 15.319  91.275  1.00 120.86 ? 296 THR C CB  1 
ATOM   9172  O OG1 . THR C 1 296 ? -24.516 15.589  91.383  1.00 111.16 ? 296 THR C OG1 1 
ATOM   9173  C CG2 . THR C 1 296 ? -26.369 14.252  92.256  1.00 108.50 ? 296 THR C CG2 1 
ATOM   9174  N N   . LYS C 1 297 ? -26.719 17.093  88.815  1.00 119.10 ? 297 LYS C N   1 
ATOM   9175  C CA  . LYS C 1 297 ? -26.664 18.159  87.830  1.00 109.73 ? 297 LYS C CA  1 
ATOM   9176  C C   . LYS C 1 297 ? -25.282 18.833  87.848  1.00 103.48 ? 297 LYS C C   1 
ATOM   9177  O O   . LYS C 1 297 ? -24.876 19.474  86.882  1.00 82.80  ? 297 LYS C O   1 
ATOM   9178  C CB  . LYS C 1 297 ? -27.830 19.112  88.130  1.00 105.74 ? 297 LYS C CB  1 
ATOM   9179  C CG  . LYS C 1 297 ? -28.283 19.991  86.971  1.00 103.94 ? 297 LYS C CG  1 
ATOM   9180  C CD  . LYS C 1 297 ? -28.797 21.352  87.381  1.00 106.16 ? 297 LYS C CD  1 
ATOM   9181  C CE  . LYS C 1 297 ? -28.470 22.417  86.356  1.00 112.08 ? 297 LYS C CE  1 
ATOM   9182  N NZ  . LYS C 1 297 ? -29.067 23.711  86.744  1.00 119.05 ? 297 LYS C NZ  1 
ATOM   9183  N N   . GLU C 1 298 ? -24.532 18.630  88.938  1.00 111.62 ? 298 GLU C N   1 
ATOM   9184  C CA  . GLU C 1 298 ? -23.426 19.500  89.317  1.00 111.76 ? 298 GLU C CA  1 
ATOM   9185  C C   . GLU C 1 298 ? -22.091 18.923  88.833  1.00 107.18 ? 298 GLU C C   1 
ATOM   9186  O O   . GLU C 1 298 ? -21.223 19.666  88.378  1.00 89.60  ? 298 GLU C O   1 
ATOM   9187  C CB  . GLU C 1 298 ? -23.430 19.685  90.835  1.00 119.85 ? 298 GLU C CB  1 
ATOM   9188  C CG  . GLU C 1 298 ? -23.377 21.141  91.251  1.00 132.33 ? 298 GLU C CG  1 
ATOM   9189  C CD  . GLU C 1 298 ? -24.535 21.991  90.734  1.00 138.16 ? 298 GLU C CD  1 
ATOM   9190  O OE1 . GLU C 1 298 ? -25.708 21.673  91.042  1.00 117.49 ? 298 GLU C OE1 1 
ATOM   9191  O OE2 . GLU C 1 298 ? -24.265 22.965  90.005  1.00 140.08 ? 298 GLU C OE2 1 
ATOM   9192  N N   . GLU C 1 299 ? -21.926 17.598  88.957  1.00 113.78 ? 299 GLU C N   1 
ATOM   9193  C CA  . GLU C 1 299 ? -20.737 16.895  88.491  1.00 110.58 ? 299 GLU C CA  1 
ATOM   9194  C C   . GLU C 1 299 ? -20.684 16.897  86.968  1.00 105.95 ? 299 GLU C C   1 
ATOM   9195  O O   . GLU C 1 299 ? -19.609 16.840  86.374  1.00 101.87 ? 299 GLU C O   1 
ATOM   9196  C CB  . GLU C 1 299 ? -20.746 15.450  88.990  1.00 114.28 ? 299 GLU C CB  1 
ATOM   9197  C CG  . GLU C 1 299 ? -20.653 15.342  90.504  1.00 118.90 ? 299 GLU C CG  1 
ATOM   9198  C CD  . GLU C 1 299 ? -21.252 14.085  91.109  1.00 118.96 ? 299 GLU C CD  1 
ATOM   9199  O OE1 . GLU C 1 299 ? -21.876 13.309  90.364  1.00 118.81 ? 299 GLU C OE1 1 
ATOM   9200  O OE2 . GLU C 1 299 ? -21.089 13.887  92.327  1.00 119.90 ? 299 GLU C OE2 1 
ATOM   9201  N N   . LEU C 1 300 ? -21.866 16.920  86.345  1.00 113.29 ? 300 LEU C N   1 
ATOM   9202  C CA  . LEU C 1 300 ? -21.971 17.073  84.906  1.00 113.15 ? 300 LEU C CA  1 
ATOM   9203  C C   . LEU C 1 300 ? -21.629 18.511  84.524  1.00 102.04 ? 300 LEU C C   1 
ATOM   9204  O O   . LEU C 1 300 ? -20.844 18.718  83.601  1.00 89.51  ? 300 LEU C O   1 
ATOM   9205  C CB  . LEU C 1 300 ? -23.384 16.699  84.447  1.00 119.02 ? 300 LEU C CB  1 
ATOM   9206  C CG  . LEU C 1 300 ? -23.560 16.559  82.933  1.00 121.61 ? 300 LEU C CG  1 
ATOM   9207  C CD1 . LEU C 1 300 ? -22.696 15.434  82.374  1.00 126.00 ? 300 LEU C CD1 1 
ATOM   9208  C CD2 . LEU C 1 300 ? -25.018 16.323  82.572  1.00 114.29 ? 300 LEU C CD2 1 
ATOM   9209  N N   . LYS C 1 301 ? -22.206 19.482  85.257  1.00 100.33 ? 301 LYS C N   1 
ATOM   9210  C CA  . LYS C 1 301 ? -22.042 20.905  84.976  1.00 103.48 ? 301 LYS C CA  1 
ATOM   9211  C C   . LYS C 1 301 ? -20.558 21.258  84.851  1.00 99.94  ? 301 LYS C C   1 
ATOM   9212  O O   . LYS C 1 301 ? -20.185 21.991  83.940  1.00 95.50  ? 301 LYS C O   1 
ATOM   9213  C CB  . LYS C 1 301 ? -22.738 21.784  86.029  1.00 88.68  ? 301 LYS C CB  1 
ATOM   9214  N N   . LYS C 1 302 ? -19.713 20.715  85.738  1.00 95.73  ? 302 LYS C N   1 
ATOM   9215  C CA  . LYS C 1 302 ? -18.297 21.041  85.716  1.00 110.70 ? 302 LYS C CA  1 
ATOM   9216  C C   . LYS C 1 302 ? -17.507 20.046  84.857  1.00 113.30 ? 302 LYS C C   1 
ATOM   9217  O O   . LYS C 1 302 ? -16.355 20.320  84.526  1.00 110.95 ? 302 LYS C O   1 
ATOM   9218  C CB  . LYS C 1 302 ? -17.745 21.162  87.142  1.00 114.47 ? 302 LYS C CB  1 
ATOM   9219  C CG  . LYS C 1 302 ? -17.740 19.886  87.979  1.00 114.12 ? 302 LYS C CG  1 
ATOM   9220  C CD  . LYS C 1 302 ? -16.507 19.739  88.862  1.00 107.57 ? 302 LYS C CD  1 
ATOM   9221  C CE  . LYS C 1 302 ? -15.216 19.609  88.076  1.00 95.54  ? 302 LYS C CE  1 
ATOM   9222  N NZ  . LYS C 1 302 ? -14.068 19.385  88.974  1.00 87.38  ? 302 LYS C NZ  1 
ATOM   9223  N N   . PHE C 1 303 ? -18.126 18.914  84.485  1.00 112.62 ? 303 PHE C N   1 
ATOM   9224  C CA  . PHE C 1 303 ? -17.493 17.963  83.587  1.00 108.29 ? 303 PHE C CA  1 
ATOM   9225  C C   . PHE C 1 303 ? -17.412 18.518  82.163  1.00 99.13  ? 303 PHE C C   1 
ATOM   9226  O O   . PHE C 1 303 ? -16.466 18.214  81.434  1.00 87.28  ? 303 PHE C O   1 
ATOM   9227  C CB  . PHE C 1 303 ? -18.222 16.617  83.544  1.00 115.54 ? 303 PHE C CB  1 
ATOM   9228  C CG  . PHE C 1 303 ? -17.723 15.773  82.399  1.00 127.96 ? 303 PHE C CG  1 
ATOM   9229  C CD1 . PHE C 1 303 ? -16.412 15.312  82.382  1.00 129.49 ? 303 PHE C CD1 1 
ATOM   9230  C CD2 . PHE C 1 303 ? -18.518 15.544  81.286  1.00 136.56 ? 303 PHE C CD2 1 
ATOM   9231  C CE1 . PHE C 1 303 ? -15.926 14.589  81.303  1.00 136.16 ? 303 PHE C CE1 1 
ATOM   9232  C CE2 . PHE C 1 303 ? -18.031 14.820  80.208  1.00 144.25 ? 303 PHE C CE2 1 
ATOM   9233  C CZ  . PHE C 1 303 ? -16.737 14.342  80.219  1.00 144.61 ? 303 PHE C CZ  1 
ATOM   9234  N N   . VAL C 1 304 ? -18.424 19.299  81.762  1.00 96.91  ? 304 VAL C N   1 
ATOM   9235  C CA  . VAL C 1 304 ? -18.454 19.917  80.442  1.00 105.83 ? 304 VAL C CA  1 
ATOM   9236  C C   . VAL C 1 304 ? -17.293 20.915  80.334  1.00 97.86  ? 304 VAL C C   1 
ATOM   9237  O O   . VAL C 1 304 ? -16.609 20.956  79.312  1.00 85.58  ? 304 VAL C O   1 
ATOM   9238  C CB  . VAL C 1 304 ? -19.830 20.564  80.138  1.00 104.39 ? 304 VAL C CB  1 
ATOM   9239  C CG1 . VAL C 1 304 ? -19.849 21.347  78.830  1.00 100.78 ? 304 VAL C CG1 1 
ATOM   9240  C CG2 . VAL C 1 304 ? -20.957 19.539  80.136  1.00 97.52  ? 304 VAL C CG2 1 
ATOM   9241  N N   . GLU C 1 305 ? -17.054 21.686  81.407  1.00 98.16  ? 305 GLU C N   1 
ATOM   9242  C CA  . GLU C 1 305 ? -16.004 22.696  81.439  1.00 102.93 ? 305 GLU C CA  1 
ATOM   9243  C C   . GLU C 1 305 ? -14.615 22.074  81.285  1.00 110.77 ? 305 GLU C C   1 
ATOM   9244  O O   . GLU C 1 305 ? -13.756 22.683  80.653  1.00 102.65 ? 305 GLU C O   1 
ATOM   9245  C CB  . GLU C 1 305 ? -16.059 23.473  82.751  1.00 101.85 ? 305 GLU C CB  1 
ATOM   9246  C CG  . GLU C 1 305 ? -17.249 24.402  82.848  1.00 102.22 ? 305 GLU C CG  1 
ATOM   9247  C CD  . GLU C 1 305 ? -17.633 24.774  84.270  1.00 108.66 ? 305 GLU C CD  1 
ATOM   9248  O OE1 . GLU C 1 305 ? -16.982 24.290  85.221  1.00 118.39 ? 305 GLU C OE1 1 
ATOM   9249  O OE2 . GLU C 1 305 ? -18.599 25.529  84.420  1.00 105.42 ? 305 GLU C OE2 1 
ATOM   9250  N N   . GLU C 1 306 ? -14.389 20.892  81.887  1.00 112.11 ? 306 GLU C N   1 
ATOM   9251  C CA  . GLU C 1 306 ? -13.115 20.183  81.770  1.00 116.79 ? 306 GLU C CA  1 
ATOM   9252  C C   . GLU C 1 306 ? -12.858 19.782  80.308  1.00 117.94 ? 306 GLU C C   1 
ATOM   9253  O O   . GLU C 1 306 ? -11.752 19.988  79.808  1.00 121.80 ? 306 GLU C O   1 
ATOM   9254  C CB  . GLU C 1 306 ? -13.031 18.970  82.719  1.00 123.38 ? 306 GLU C CB  1 
ATOM   9255  C CG  . GLU C 1 306 ? -12.945 19.326  84.213  1.00 123.05 ? 306 GLU C CG  1 
ATOM   9256  C CD  . GLU C 1 306 ? -12.307 18.317  85.171  1.00 115.61 ? 306 GLU C CD  1 
ATOM   9257  O OE1 . GLU C 1 306 ? -11.548 17.433  84.718  1.00 103.07 ? 306 GLU C OE1 1 
ATOM   9258  O OE2 . GLU C 1 306 ? -12.567 18.414  86.385  1.00 101.05 ? 306 GLU C OE2 1 
ATOM   9259  N N   . THR C 1 307 ? -13.876 19.224  79.622  1.00 120.61 ? 307 THR C N   1 
ATOM   9260  C CA  . THR C 1 307 ? -13.751 18.804  78.227  1.00 105.33 ? 307 THR C CA  1 
ATOM   9261  C C   . THR C 1 307 ? -13.510 20.012  77.317  1.00 98.67  ? 307 THR C C   1 
ATOM   9262  O O   . THR C 1 307 ? -12.808 19.896  76.312  1.00 83.81  ? 307 THR C O   1 
ATOM   9263  C CB  . THR C 1 307 ? -14.993 18.056  77.701  1.00 102.11 ? 307 THR C CB  1 
ATOM   9264  O OG1 . THR C 1 307 ? -15.557 17.199  78.696  1.00 88.47  ? 307 THR C OG1 1 
ATOM   9265  C CG2 . THR C 1 307 ? -14.692 17.244  76.456  1.00 93.17  ? 307 THR C CG2 1 
ATOM   9266  N N   . LEU C 1 308 ? -14.118 21.157  77.670  1.00 98.14  ? 308 LEU C N   1 
ATOM   9267  C CA  . LEU C 1 308 ? -14.171 22.327  76.800  1.00 104.83 ? 308 LEU C CA  1 
ATOM   9268  C C   . LEU C 1 308 ? -12.872 23.125  76.880  1.00 110.33 ? 308 LEU C C   1 
ATOM   9269  O O   . LEU C 1 308 ? -12.246 23.369  75.851  1.00 111.29 ? 308 LEU C O   1 
ATOM   9270  C CB  . LEU C 1 308 ? -15.364 23.219  77.167  1.00 99.03  ? 308 LEU C CB  1 
ATOM   9271  C CG  . LEU C 1 308 ? -16.685 22.933  76.449  1.00 92.89  ? 308 LEU C CG  1 
ATOM   9272  C CD1 . LEU C 1 308 ? -17.702 24.036  76.744  1.00 87.03  ? 308 LEU C CD1 1 
ATOM   9273  C CD2 . LEU C 1 308 ? -16.484 22.775  74.947  1.00 87.24  ? 308 LEU C CD2 1 
ATOM   9274  N N   . SER C 1 309 ? -12.484 23.541  78.094  1.00 117.97 ? 309 SER C N   1 
ATOM   9275  C CA  . SER C 1 309 ? -11.311 24.387  78.274  1.00 125.36 ? 309 SER C CA  1 
ATOM   9276  C C   . SER C 1 309 ? -10.011 23.570  78.244  1.00 120.59 ? 309 SER C C   1 
ATOM   9277  O O   . SER C 1 309 ? -8.947  24.109  78.551  1.00 103.54 ? 309 SER C O   1 
ATOM   9278  C CB  . SER C 1 309 ? -11.435 25.238  79.527  1.00 122.93 ? 309 SER C CB  1 
ATOM   9279  O OG  . SER C 1 309 ? -11.804 24.458  80.657  1.00 110.39 ? 309 SER C OG  1 
ATOM   9280  N N   . SER C 1 310 ? -10.096 22.282  77.856  1.00 121.99 ? 310 SER C N   1 
ATOM   9281  C CA  . SER C 1 310 ? -8.928  21.493  77.476  1.00 119.75 ? 310 SER C CA  1 
ATOM   9282  C C   . SER C 1 310 ? -8.973  21.110  75.988  1.00 113.68 ? 310 SER C C   1 
ATOM   9283  O O   . SER C 1 310 ? -8.260  20.203  75.563  1.00 97.39  ? 310 SER C O   1 
ATOM   9284  C CB  . SER C 1 310 ? -8.739  20.280  78.395  1.00 114.17 ? 310 SER C CB  1 
ATOM   9285  O OG  . SER C 1 310 ? -9.755  19.300  78.229  1.00 89.67  ? 310 SER C OG  1 
ATOM   9286  N N   . GLY C 1 311 ? -9.807  21.810  75.198  1.00 108.16 ? 311 GLY C N   1 
ATOM   9287  C CA  . GLY C 1 311 ? -9.672  21.876  73.748  1.00 104.29 ? 311 GLY C CA  1 
ATOM   9288  C C   . GLY C 1 311 ? -10.366 20.736  73.002  1.00 107.65 ? 311 GLY C C   1 
ATOM   9289  O O   . GLY C 1 311 ? -9.720  20.063  72.198  1.00 100.39 ? 311 GLY C O   1 
ATOM   9290  N N   . GLN C 1 312 ? -11.681 20.555  73.243  1.00 112.78 ? 312 GLN C N   1 
ATOM   9291  C CA  . GLN C 1 312 ? -12.468 19.508  72.591  1.00 116.53 ? 312 GLN C CA  1 
ATOM   9292  C C   . GLN C 1 312 ? -13.947 19.901  72.471  1.00 103.15 ? 312 GLN C C   1 
ATOM   9293  O O   . GLN C 1 312 ? -14.469 20.596  73.345  1.00 87.91  ? 312 GLN C O   1 
ATOM   9294  C CB  . GLN C 1 312 ? -12.311 18.182  73.340  1.00 112.62 ? 312 GLN C CB  1 
ATOM   9295  C CG  . GLN C 1 312 ? -10.938 17.544  73.157  1.00 108.11 ? 312 GLN C CG  1 
ATOM   9296  C CD  . GLN C 1 312 ? -11.045 16.043  73.189  1.00 103.16 ? 312 GLN C CD  1 
ATOM   9297  O OE1 . GLN C 1 312 ? -11.680 15.484  74.080  1.00 92.09  ? 312 GLN C OE1 1 
ATOM   9298  N NE2 . GLN C 1 312 ? -10.472 15.388  72.188  1.00 98.08  ? 312 GLN C NE2 1 
ATOM   9299  N N   . VAL C 1 313 ? -14.607 19.422  71.388  1.00 93.91  ? 313 VAL C N   1 
ATOM   9300  C CA  . VAL C 1 313 ? -16.012 19.713  71.090  1.00 90.27  ? 313 VAL C CA  1 
ATOM   9301  C C   . VAL C 1 313 ? -16.908 18.972  72.092  1.00 97.72  ? 313 VAL C C   1 
ATOM   9302  O O   . VAL C 1 313 ? -16.458 18.032  72.754  1.00 94.90  ? 313 VAL C O   1 
ATOM   9303  C CB  . VAL C 1 313 ? -16.444 19.396  69.626  1.00 76.65  ? 313 VAL C CB  1 
ATOM   9304  C CG1 . VAL C 1 313 ? -15.775 20.288  68.585  1.00 66.47  ? 313 VAL C CG1 1 
ATOM   9305  C CG2 . VAL C 1 313 ? -16.296 17.924  69.234  1.00 72.56  ? 313 VAL C CG2 1 
ATOM   9306  N N   . ILE C 1 314 ? -18.162 19.449  72.228  1.00 97.54  ? 314 ILE C N   1 
ATOM   9307  C CA  . ILE C 1 314 ? -19.281 18.655  72.729  1.00 102.41 ? 314 ILE C CA  1 
ATOM   9308  C C   . ILE C 1 314 ? -20.054 18.140  71.510  1.00 99.62  ? 314 ILE C C   1 
ATOM   9309  O O   . ILE C 1 314 ? -20.602 18.948  70.762  1.00 92.06  ? 314 ILE C O   1 
ATOM   9310  C CB  . ILE C 1 314 ? -20.186 19.476  73.683  1.00 100.44 ? 314 ILE C CB  1 
ATOM   9311  C CG1 . ILE C 1 314 ? -19.388 20.148  74.806  1.00 105.30 ? 314 ILE C CG1 1 
ATOM   9312  C CG2 . ILE C 1 314 ? -21.315 18.625  74.259  1.00 90.75  ? 314 ILE C CG2 1 
ATOM   9313  C CD1 . ILE C 1 314 ? -18.866 19.191  75.870  1.00 105.86 ? 314 ILE C CD1 1 
ATOM   9314  N N   . PRO C 1 315 ? -20.112 16.810  71.237  1.00 96.16  ? 315 PRO C N   1 
ATOM   9315  C CA  . PRO C 1 315 ? -20.750 16.305  70.013  1.00 93.44  ? 315 PRO C CA  1 
ATOM   9316  C C   . PRO C 1 315 ? -22.282 16.415  70.025  1.00 84.06  ? 315 PRO C C   1 
ATOM   9317  O O   . PRO C 1 315 ? -22.929 16.223  71.063  1.00 65.83  ? 315 PRO C O   1 
ATOM   9318  C CB  . PRO C 1 315 ? -20.298 14.834  69.933  1.00 89.55  ? 315 PRO C CB  1 
ATOM   9319  C CG  . PRO C 1 315 ? -19.228 14.683  71.006  1.00 89.39  ? 315 PRO C CG  1 
ATOM   9320  C CD  . PRO C 1 315 ? -19.561 15.719  72.058  1.00 86.67  ? 315 PRO C CD  1 
ATOM   9321  N N   . GLY C 1 316 ? -22.853 16.751  68.856  1.00 76.73  ? 316 GLY C N   1 
ATOM   9322  C CA  . GLY C 1 316 ? -24.293 16.910  68.706  1.00 73.86  ? 316 GLY C CA  1 
ATOM   9323  C C   . GLY C 1 316 ? -24.811 18.251  69.239  1.00 72.09  ? 316 GLY C C   1 
ATOM   9324  O O   . GLY C 1 316 ? -26.019 18.462  69.333  1.00 67.53  ? 316 GLY C O   1 
ATOM   9325  N N   . TYR C 1 317 ? -23.883 19.140  69.616  1.00 74.20  ? 317 TYR C N   1 
ATOM   9326  C CA  . TYR C 1 317 ? -24.142 20.565  69.747  1.00 71.30  ? 317 TYR C CA  1 
ATOM   9327  C C   . TYR C 1 317 ? -23.381 21.253  68.611  1.00 70.96  ? 317 TYR C C   1 
ATOM   9328  O O   . TYR C 1 317 ? -22.208 20.935  68.405  1.00 58.81  ? 317 TYR C O   1 
ATOM   9329  C CB  . TYR C 1 317 ? -23.772 21.035  71.162  1.00 65.05  ? 317 TYR C CB  1 
ATOM   9330  C CG  . TYR C 1 317 ? -24.706 20.522  72.235  1.00 66.92  ? 317 TYR C CG  1 
ATOM   9331  C CD1 . TYR C 1 317 ? -24.682 19.192  72.669  1.00 65.18  ? 317 TYR C CD1 1 
ATOM   9332  C CD2 . TYR C 1 317 ? -25.655 21.369  72.808  1.00 64.02  ? 317 TYR C CD2 1 
ATOM   9333  C CE1 . TYR C 1 317 ? -25.557 18.735  73.656  1.00 61.72  ? 317 TYR C CE1 1 
ATOM   9334  C CE2 . TYR C 1 317 ? -26.541 20.927  73.788  1.00 58.32  ? 317 TYR C CE2 1 
ATOM   9335  C CZ  . TYR C 1 317 ? -26.504 19.602  74.203  1.00 62.78  ? 317 TYR C CZ  1 
ATOM   9336  O OH  . TYR C 1 317 ? -27.439 19.229  75.147  1.00 55.45  ? 317 TYR C OH  1 
ATOM   9337  N N   . GLY C 1 318 ? -24.075 22.097  67.823  1.00 75.73  ? 318 GLY C N   1 
ATOM   9338  C CA  . GLY C 1 318 ? -23.430 22.941  66.817  1.00 84.80  ? 318 GLY C CA  1 
ATOM   9339  C C   . GLY C 1 318 ? -23.647 22.477  65.372  1.00 85.35  ? 318 GLY C C   1 
ATOM   9340  O O   . GLY C 1 318 ? -23.478 21.299  65.069  1.00 107.21 ? 318 GLY C O   1 
ATOM   9341  N N   . HIS C 1 319 ? -23.959 23.424  64.474  1.00 79.62  ? 319 HIS C N   1 
ATOM   9342  C CA  . HIS C 1 319 ? -24.389 23.127  63.110  1.00 84.43  ? 319 HIS C CA  1 
ATOM   9343  C C   . HIS C 1 319 ? -23.984 24.272  62.175  1.00 78.21  ? 319 HIS C C   1 
ATOM   9344  O O   . HIS C 1 319 ? -23.881 25.413  62.619  1.00 78.81  ? 319 HIS C O   1 
ATOM   9345  C CB  . HIS C 1 319 ? -25.913 22.893  63.108  1.00 88.78  ? 319 HIS C CB  1 
ATOM   9346  C CG  . HIS C 1 319 ? -26.494 22.215  61.897  1.00 87.74  ? 319 HIS C CG  1 
ATOM   9347  N ND1 . HIS C 1 319 ? -26.774 22.856  60.709  1.00 80.62  ? 319 HIS C ND1 1 
ATOM   9348  C CD2 . HIS C 1 319 ? -26.899 20.914  61.755  1.00 83.26  ? 319 HIS C CD2 1 
ATOM   9349  C CE1 . HIS C 1 319 ? -27.293 21.975  59.854  1.00 81.61  ? 319 HIS C CE1 1 
ATOM   9350  N NE2 . HIS C 1 319 ? -27.372 20.758  60.482  1.00 74.23  ? 319 HIS C NE2 1 
ATOM   9351  N N   . ALA C 1 320 ? -23.816 23.978  60.877  1.00 74.31  ? 320 ALA C N   1 
ATOM   9352  C CA  . ALA C 1 320 ? -23.284 24.937  59.914  1.00 85.08  ? 320 ALA C CA  1 
ATOM   9353  C C   . ALA C 1 320 ? -24.318 25.970  59.434  1.00 84.69  ? 320 ALA C C   1 
ATOM   9354  O O   . ALA C 1 320 ? -23.968 26.850  58.640  1.00 84.33  ? 320 ALA C O   1 
ATOM   9355  C CB  . ALA C 1 320 ? -22.704 24.189  58.731  1.00 94.78  ? 320 ALA C CB  1 
ATOM   9356  N N   . VAL C 1 321 ? -25.578 25.865  59.872  1.00 75.68  ? 321 VAL C N   1 
ATOM   9357  C CA  . VAL C 1 321 ? -26.622 26.880  59.513  1.00 71.00  ? 321 VAL C CA  1 
ATOM   9358  C C   . VAL C 1 321 ? -27.449 27.202  60.759  1.00 63.54  ? 321 VAL C C   1 
ATOM   9359  O O   . VAL C 1 321 ? -27.525 28.380  61.116  1.00 53.54  ? 321 VAL C O   1 
ATOM   9360  C CB  . VAL C 1 321 ? -27.534 26.407  58.364  1.00 69.52  ? 321 VAL C CB  1 
ATOM   9361  C CG1 . VAL C 1 321 ? -28.698 27.357  58.135  1.00 59.86  ? 321 VAL C CG1 1 
ATOM   9362  C CG2 . VAL C 1 321 ? -26.770 26.179  57.069  1.00 64.13  ? 321 VAL C CG2 1 
ATOM   9363  N N   . LEU C 1 322 ? -28.071 26.193  61.361  1.00 64.72  ? 322 LEU C N   1 
ATOM   9364  C CA  . LEU C 1 322 ? -28.827 26.357  62.598  1.00 62.85  ? 322 LEU C CA  1 
ATOM   9365  C C   . LEU C 1 322 ? -28.055 27.221  63.586  1.00 64.15  ? 322 LEU C C   1 
ATOM   9366  O O   . LEU C 1 322 ? -26.844 27.033  63.729  1.00 59.15  ? 322 LEU C O   1 
ATOM   9367  C CB  . LEU C 1 322 ? -29.048 24.983  63.236  1.00 70.19  ? 322 LEU C CB  1 
ATOM   9368  C CG  . LEU C 1 322 ? -30.300 24.225  62.812  1.00 69.21  ? 322 LEU C CG  1 
ATOM   9369  C CD1 . LEU C 1 322 ? -30.271 22.792  63.353  1.00 66.76  ? 322 LEU C CD1 1 
ATOM   9370  C CD2 . LEU C 1 322 ? -31.545 24.973  63.285  1.00 68.06  ? 322 LEU C CD2 1 
ATOM   9371  N N   . ARG C 1 323 ? -28.789 28.139  64.244  1.00 62.56  ? 323 ARG C N   1 
ATOM   9372  C CA  . ARG C 1 323 ? -28.289 28.953  65.342  1.00 61.65  ? 323 ARG C CA  1 
ATOM   9373  C C   . ARG C 1 323 ? -29.120 28.708  66.609  1.00 63.06  ? 323 ARG C C   1 
ATOM   9374  O O   . ARG C 1 323 ? -28.751 29.198  67.668  1.00 69.38  ? 323 ARG C O   1 
ATOM   9375  C CB  . ARG C 1 323 ? -28.286 30.442  64.963  1.00 68.85  ? 323 ARG C CB  1 
ATOM   9376  C CG  . ARG C 1 323 ? -26.943 31.015  64.518  1.00 70.88  ? 323 ARG C CG  1 
ATOM   9377  C CD  . ARG C 1 323 ? -26.662 30.799  63.046  1.00 79.45  ? 323 ARG C CD  1 
ATOM   9378  N NE  . ARG C 1 323 ? -25.233 30.823  62.709  1.00 88.64  ? 323 ARG C NE  1 
ATOM   9379  C CZ  . ARG C 1 323 ? -24.546 29.808  62.171  1.00 85.25  ? 323 ARG C CZ  1 
ATOM   9380  N NH1 . ARG C 1 323 ? -24.868 28.552  62.429  1.00 71.05  ? 323 ARG C NH1 1 
ATOM   9381  N NH2 . ARG C 1 323 ? -23.508 30.055  61.392  1.00 84.39  ? 323 ARG C NH2 1 
ATOM   9382  N N   . LYS C 1 324 ? -30.210 27.930  66.537  1.00 73.89  ? 324 LYS C N   1 
ATOM   9383  C CA  . LYS C 1 324 ? -31.007 27.620  67.723  1.00 85.74  ? 324 LYS C CA  1 
ATOM   9384  C C   . LYS C 1 324 ? -31.173 26.113  67.934  1.00 81.76  ? 324 LYS C C   1 
ATOM   9385  O O   . LYS C 1 324 ? -30.628 25.301  67.181  1.00 76.15  ? 324 LYS C O   1 
ATOM   9386  C CB  . LYS C 1 324 ? -32.404 28.231  67.615  1.00 98.10  ? 324 LYS C CB  1 
ATOM   9387  C CG  . LYS C 1 324 ? -32.454 29.748  67.579  1.00 100.38 ? 324 LYS C CG  1 
ATOM   9388  C CD  . LYS C 1 324 ? -32.082 30.416  68.859  1.00 97.16  ? 324 LYS C CD  1 
ATOM   9389  C CE  . LYS C 1 324 ? -32.775 31.758  68.960  1.00 97.00  ? 324 LYS C CE  1 
ATOM   9390  N NZ  . LYS C 1 324 ? -31.940 32.726  69.698  1.00 106.85 ? 324 LYS C NZ  1 
ATOM   9391  N N   . THR C 1 325 ? -31.908 25.768  69.010  1.00 79.73  ? 325 THR C N   1 
ATOM   9392  C CA  . THR C 1 325 ? -32.341 24.404  69.285  1.00 79.66  ? 325 THR C CA  1 
ATOM   9393  C C   . THR C 1 325 ? -32.966 23.849  68.001  1.00 79.36  ? 325 THR C C   1 
ATOM   9394  O O   . THR C 1 325 ? -33.757 24.538  67.362  1.00 85.63  ? 325 THR C O   1 
ATOM   9395  C CB  . THR C 1 325 ? -33.309 24.345  70.485  1.00 77.03  ? 325 THR C CB  1 
ATOM   9396  O OG1 . THR C 1 325 ? -32.727 24.896  71.671  1.00 72.23  ? 325 THR C OG1 1 
ATOM   9397  C CG2 . THR C 1 325 ? -33.754 22.938  70.828  1.00 74.83  ? 325 THR C CG2 1 
ATOM   9398  N N   . ASP C 1 326 ? -32.565 22.633  67.602  1.00 62.78  ? 326 ASP C N   1 
ATOM   9399  C CA  . ASP C 1 326 ? -33.201 21.917  66.509  1.00 58.62  ? 326 ASP C CA  1 
ATOM   9400  C C   . ASP C 1 326 ? -34.569 21.382  66.953  1.00 61.15  ? 326 ASP C C   1 
ATOM   9401  O O   . ASP C 1 326 ? -34.655 20.595  67.891  1.00 56.08  ? 326 ASP C O   1 
ATOM   9402  C CB  . ASP C 1 326 ? -32.309 20.767  66.041  1.00 59.06  ? 326 ASP C CB  1 
ATOM   9403  C CG  . ASP C 1 326 ? -32.662 20.182  64.686  1.00 60.94  ? 326 ASP C CG  1 
ATOM   9404  O OD1 . ASP C 1 326 ? -33.753 20.509  64.128  1.00 54.18  ? 326 ASP C OD1 1 
ATOM   9405  O OD2 . ASP C 1 326 ? -31.813 19.421  64.176  1.00 65.01  ? 326 ASP C OD2 1 
ATOM   9406  N N   . PRO C 1 327 ? -35.691 21.744  66.288  1.00 61.80  ? 327 PRO C N   1 
ATOM   9407  C CA  . PRO C 1 327 ? -37.010 21.197  66.657  1.00 57.45  ? 327 PRO C CA  1 
ATOM   9408  C C   . PRO C 1 327 ? -37.159 19.693  66.394  1.00 61.96  ? 327 PRO C C   1 
ATOM   9409  O O   . PRO C 1 327 ? -38.102 19.050  66.882  1.00 62.00  ? 327 PRO C O   1 
ATOM   9410  C CB  . PRO C 1 327 ? -37.974 21.958  65.733  1.00 56.53  ? 327 PRO C CB  1 
ATOM   9411  C CG  . PRO C 1 327 ? -37.109 22.339  64.522  1.00 51.39  ? 327 PRO C CG  1 
ATOM   9412  C CD  . PRO C 1 327 ? -35.745 22.636  65.114  1.00 55.19  ? 327 PRO C CD  1 
ATOM   9413  N N   . ARG C 1 328 ? -36.244 19.160  65.558  1.00 56.15  ? 328 ARG C N   1 
ATOM   9414  C CA  . ARG C 1 328 ? -36.075 17.726  65.387  1.00 52.39  ? 328 ARG C CA  1 
ATOM   9415  C C   . ARG C 1 328 ? -35.551 17.117  66.685  1.00 48.47  ? 328 ARG C C   1 
ATOM   9416  O O   . ARG C 1 328 ? -36.057 16.083  67.106  1.00 42.35  ? 328 ARG C O   1 
ATOM   9417  C CB  . ARG C 1 328 ? -35.112 17.417  64.242  1.00 47.67  ? 328 ARG C CB  1 
ATOM   9418  C CG  . ARG C 1 328 ? -35.615 17.867  62.888  1.00 51.93  ? 328 ARG C CG  1 
ATOM   9419  C CD  . ARG C 1 328 ? -34.683 17.475  61.770  1.00 54.07  ? 328 ARG C CD  1 
ATOM   9420  N NE  . ARG C 1 328 ? -33.367 18.063  61.883  1.00 50.69  ? 328 ARG C NE  1 
ATOM   9421  C CZ  . ARG C 1 328 ? -32.336 17.720  61.116  1.00 62.32  ? 328 ARG C CZ  1 
ATOM   9422  N NH1 . ARG C 1 328 ? -32.529 16.958  60.049  1.00 69.16  ? 328 ARG C NH1 1 
ATOM   9423  N NH2 . ARG C 1 328 ? -31.121 18.156  61.415  1.00 73.52  ? 328 ARG C NH2 1 
ATOM   9424  N N   . TYR C 1 329 ? -34.562 17.776  67.313  1.00 46.71  ? 329 TYR C N   1 
ATOM   9425  C CA  . TYR C 1 329 ? -34.127 17.409  68.656  1.00 57.02  ? 329 TYR C CA  1 
ATOM   9426  C C   . TYR C 1 329 ? -35.342 17.402  69.602  1.00 54.22  ? 329 TYR C C   1 
ATOM   9427  O O   . TYR C 1 329 ? -35.626 16.411  70.275  1.00 50.07  ? 329 TYR C O   1 
ATOM   9428  C CB  . TYR C 1 329 ? -32.957 18.307  69.118  1.00 57.50  ? 329 TYR C CB  1 
ATOM   9429  C CG  . TYR C 1 329 ? -32.524 18.054  70.543  1.00 59.43  ? 329 TYR C CG  1 
ATOM   9430  C CD1 . TYR C 1 329 ? -33.303 18.469  71.620  1.00 55.29  ? 329 TYR C CD1 1 
ATOM   9431  C CD2 . TYR C 1 329 ? -31.387 17.313  70.824  1.00 61.23  ? 329 TYR C CD2 1 
ATOM   9432  C CE1 . TYR C 1 329 ? -32.944 18.189  72.931  1.00 54.87  ? 329 TYR C CE1 1 
ATOM   9433  C CE2 . TYR C 1 329 ? -31.012 17.027  72.131  1.00 65.37  ? 329 TYR C CE2 1 
ATOM   9434  C CZ  . TYR C 1 329 ? -31.792 17.466  73.192  1.00 60.69  ? 329 TYR C CZ  1 
ATOM   9435  O OH  . TYR C 1 329 ? -31.426 17.175  74.493  1.00 57.11  ? 329 TYR C OH  1 
ATOM   9436  N N   . VAL C 1 330 ? -36.088 18.510  69.618  1.00 55.43  ? 330 VAL C N   1 
ATOM   9437  C CA  . VAL C 1 330 ? -37.182 18.695  70.555  1.00 60.22  ? 330 VAL C CA  1 
ATOM   9438  C C   . VAL C 1 330 ? -38.203 17.557  70.424  1.00 57.17  ? 330 VAL C C   1 
ATOM   9439  O O   . VAL C 1 330 ? -38.767 17.136  71.433  1.00 58.32  ? 330 VAL C O   1 
ATOM   9440  C CB  . VAL C 1 330 ? -37.849 20.080  70.383  1.00 61.82  ? 330 VAL C CB  1 
ATOM   9441  C CG1 . VAL C 1 330 ? -39.039 20.236  71.327  1.00 59.71  ? 330 VAL C CG1 1 
ATOM   9442  C CG2 . VAL C 1 330 ? -36.860 21.233  70.557  1.00 56.65  ? 330 VAL C CG2 1 
ATOM   9443  N N   . ALA C 1 331 ? -38.449 17.072  69.198  1.00 51.13  ? 331 ALA C N   1 
ATOM   9444  C CA  . ALA C 1 331 ? -39.465 16.047  68.958  1.00 52.38  ? 331 ALA C CA  1 
ATOM   9445  C C   . ALA C 1 331 ? -38.993 14.687  69.475  1.00 55.54  ? 331 ALA C C   1 
ATOM   9446  O O   . ALA C 1 331 ? -39.815 13.837  69.828  1.00 52.07  ? 331 ALA C O   1 
ATOM   9447  C CB  . ALA C 1 331 ? -39.820 15.968  67.489  1.00 45.17  ? 331 ALA C CB  1 
ATOM   9448  N N   . GLN C 1 332 ? -37.665 14.491  69.511  1.00 57.22  ? 332 GLN C N   1 
ATOM   9449  C CA  . GLN C 1 332 ? -37.074 13.283  70.073  1.00 57.83  ? 332 GLN C CA  1 
ATOM   9450  C C   . GLN C 1 332 ? -37.305 13.313  71.581  1.00 56.88  ? 332 GLN C C   1 
ATOM   9451  O O   . GLN C 1 332 ? -37.816 12.353  72.152  1.00 55.44  ? 332 GLN C O   1 
ATOM   9452  C CB  . GLN C 1 332 ? -35.567 13.180  69.794  1.00 59.61  ? 332 GLN C CB  1 
ATOM   9453  C CG  . GLN C 1 332 ? -35.162 13.134  68.323  1.00 64.20  ? 332 GLN C CG  1 
ATOM   9454  C CD  . GLN C 1 332 ? -35.393 11.794  67.659  1.00 69.52  ? 332 GLN C CD  1 
ATOM   9455  O OE1 . GLN C 1 332 ? -36.450 11.173  67.830  1.00 63.31  ? 332 GLN C OE1 1 
ATOM   9456  N NE2 . GLN C 1 332 ? -34.393 11.343  66.901  1.00 65.47  ? 332 GLN C NE2 1 
ATOM   9457  N N   . ARG C 1 333 ? -36.928 14.449  72.192  1.00 56.85  ? 333 ARG C N   1 
ATOM   9458  C CA  . ARG C 1 333 ? -37.130 14.720  73.610  1.00 61.99  ? 333 ARG C CA  1 
ATOM   9459  C C   . ARG C 1 333 ? -38.575 14.427  74.052  1.00 51.90  ? 333 ARG C C   1 
ATOM   9460  O O   . ARG C 1 333 ? -38.803 13.887  75.127  1.00 45.33  ? 333 ARG C O   1 
ATOM   9461  C CB  . ARG C 1 333 ? -36.695 16.163  73.885  1.00 66.60  ? 333 ARG C CB  1 
ATOM   9462  C CG  . ARG C 1 333 ? -36.801 16.567  75.346  1.00 70.73  ? 333 ARG C CG  1 
ATOM   9463  C CD  . ARG C 1 333 ? -36.313 17.979  75.624  1.00 73.37  ? 333 ARG C CD  1 
ATOM   9464  N NE  . ARG C 1 333 ? -36.461 18.288  77.043  1.00 75.55  ? 333 ARG C NE  1 
ATOM   9465  C CZ  . ARG C 1 333 ? -35.863 17.619  78.027  1.00 78.69  ? 333 ARG C CZ  1 
ATOM   9466  N NH1 . ARG C 1 333 ? -34.572 17.337  77.944  1.00 77.36  ? 333 ARG C NH1 1 
ATOM   9467  N NH2 . ARG C 1 333 ? -36.560 17.242  79.091  1.00 73.30  ? 333 ARG C NH2 1 
ATOM   9468  N N   . GLU C 1 334 ? -39.557 14.732  73.203  1.00 58.87  ? 334 GLU C N   1 
ATOM   9469  C CA  . GLU C 1 334 ? -40.960 14.585  73.568  1.00 67.51  ? 334 GLU C CA  1 
ATOM   9470  C C   . GLU C 1 334 ? -41.375 13.122  73.561  1.00 60.30  ? 334 GLU C C   1 
ATOM   9471  O O   . GLU C 1 334 ? -42.093 12.695  74.461  1.00 75.24  ? 334 GLU C O   1 
ATOM   9472  C CB  . GLU C 1 334 ? -41.836 15.446  72.659  1.00 78.01  ? 334 GLU C CB  1 
ATOM   9473  C CG  . GLU C 1 334 ? -41.381 16.902  72.689  1.00 90.09  ? 334 GLU C CG  1 
ATOM   9474  C CD  . GLU C 1 334 ? -42.436 17.975  72.525  1.00 99.78  ? 334 GLU C CD  1 
ATOM   9475  O OE1 . GLU C 1 334 ? -42.040 19.164  72.537  1.00 93.68  ? 334 GLU C OE1 1 
ATOM   9476  O OE2 . GLU C 1 334 ? -43.633 17.619  72.390  1.00 109.51 ? 334 GLU C OE2 1 
ATOM   9477  N N   . PHE C 1 335 ? -40.911 12.368  72.558  1.00 58.68  ? 335 PHE C N   1 
ATOM   9478  C CA  . PHE C 1 335 ? -41.047 10.915  72.530  1.00 52.85  ? 335 PHE C CA  1 
ATOM   9479  C C   . PHE C 1 335 ? -40.446 10.282  73.789  1.00 51.80  ? 335 PHE C C   1 
ATOM   9480  O O   . PHE C 1 335 ? -41.015 9.351   74.356  1.00 49.21  ? 335 PHE C O   1 
ATOM   9481  C CB  . PHE C 1 335 ? -40.359 10.322  71.289  1.00 52.57  ? 335 PHE C CB  1 
ATOM   9482  C CG  . PHE C 1 335 ? -40.673 8.861   71.082  1.00 57.87  ? 335 PHE C CG  1 
ATOM   9483  C CD1 . PHE C 1 335 ? -41.873 8.477   70.496  1.00 58.39  ? 335 PHE C CD1 1 
ATOM   9484  C CD2 . PHE C 1 335 ? -39.833 7.866   71.572  1.00 60.26  ? 335 PHE C CD2 1 
ATOM   9485  C CE1 . PHE C 1 335 ? -42.210 7.137   70.359  1.00 54.97  ? 335 PHE C CE1 1 
ATOM   9486  C CE2 . PHE C 1 335 ? -40.178 6.523   71.456  1.00 60.57  ? 335 PHE C CE2 1 
ATOM   9487  C CZ  . PHE C 1 335 ? -41.368 6.164   70.852  1.00 58.13  ? 335 PHE C CZ  1 
ATOM   9488  N N   . ALA C 1 336 ? -39.279 10.782  74.212  1.00 54.47  ? 336 ALA C N   1 
ATOM   9489  C CA  . ALA C 1 336 ? -38.456 10.117  75.211  1.00 59.53  ? 336 ALA C CA  1 
ATOM   9490  C C   . ALA C 1 336 ? -38.995 10.367  76.621  1.00 60.44  ? 336 ALA C C   1 
ATOM   9491  O O   . ALA C 1 336 ? -38.928 9.474   77.462  1.00 60.79  ? 336 ALA C O   1 
ATOM   9492  C CB  . ALA C 1 336 ? -37.009 10.560  75.055  1.00 57.95  ? 336 ALA C CB  1 
ATOM   9493  N N   . LEU C 1 337 ? -39.505 11.579  76.878  1.00 64.63  ? 337 LEU C N   1 
ATOM   9494  C CA  . LEU C 1 337 ? -40.211 11.890  78.122  1.00 77.24  ? 337 LEU C CA  1 
ATOM   9495  C C   . LEU C 1 337 ? -41.408 10.948  78.303  1.00 73.46  ? 337 LEU C C   1 
ATOM   9496  O O   . LEU C 1 337 ? -41.603 10.378  79.376  1.00 70.05  ? 337 LEU C O   1 
ATOM   9497  C CB  . LEU C 1 337 ? -40.653 13.365  78.110  1.00 82.52  ? 337 LEU C CB  1 
ATOM   9498  C CG  . LEU C 1 337 ? -39.541 14.405  78.315  1.00 83.57  ? 337 LEU C CG  1 
ATOM   9499  C CD1 . LEU C 1 337 ? -39.982 15.794  77.865  1.00 77.64  ? 337 LEU C CD1 1 
ATOM   9500  C CD2 . LEU C 1 337 ? -39.075 14.440  79.769  1.00 80.90  ? 337 LEU C CD2 1 
ATOM   9501  N N   . LYS C 1 338 ? -42.196 10.781  77.235  1.00 74.14  ? 338 LYS C N   1 
ATOM   9502  C CA  . LYS C 1 338 ? -43.359 9.906   77.256  1.00 86.12  ? 338 LYS C CA  1 
ATOM   9503  C C   . LYS C 1 338 ? -42.984 8.439   77.506  1.00 90.06  ? 338 LYS C C   1 
ATOM   9504  O O   . LYS C 1 338 ? -43.686 7.763   78.256  1.00 79.52  ? 338 LYS C O   1 
ATOM   9505  C CB  . LYS C 1 338 ? -44.138 10.003  75.936  1.00 92.46  ? 338 LYS C CB  1 
ATOM   9506  C CG  . LYS C 1 338 ? -45.153 11.140  75.823  1.00 96.24  ? 338 LYS C CG  1 
ATOM   9507  C CD  . LYS C 1 338 ? -46.432 10.714  75.109  1.00 99.24  ? 338 LYS C CD  1 
ATOM   9508  C CE  . LYS C 1 338 ? -47.223 9.665   75.876  1.00 102.49 ? 338 LYS C CE  1 
ATOM   9509  N NZ  . LYS C 1 338 ? -47.540 8.468   75.055  1.00 91.23  ? 338 LYS C NZ  1 
ATOM   9510  N N   . HIS C 1 339 ? -41.896 7.950   76.876  1.00 83.78  ? 339 HIS C N   1 
ATOM   9511  C CA  . HIS C 1 339 ? -41.698 6.525   76.628  1.00 64.97  ? 339 HIS C CA  1 
ATOM   9512  C C   . HIS C 1 339 ? -40.515 5.904   77.376  1.00 61.38  ? 339 HIS C C   1 
ATOM   9513  O O   . HIS C 1 339 ? -40.417 4.685   77.464  1.00 55.53  ? 339 HIS C O   1 
ATOM   9514  C CB  . HIS C 1 339 ? -41.504 6.338   75.133  1.00 61.99  ? 339 HIS C CB  1 
ATOM   9515  C CG  . HIS C 1 339 ? -42.782 6.318   74.370  1.00 62.63  ? 339 HIS C CG  1 
ATOM   9516  N ND1 . HIS C 1 339 ? -43.524 5.181   74.206  1.00 63.00  ? 339 HIS C ND1 1 
ATOM   9517  C CD2 . HIS C 1 339 ? -43.394 7.322   73.681  1.00 60.07  ? 339 HIS C CD2 1 
ATOM   9518  C CE1 . HIS C 1 339 ? -44.593 5.474   73.464  1.00 68.55  ? 339 HIS C CE1 1 
ATOM   9519  N NE2 . HIS C 1 339 ? -44.543 6.806   73.148  1.00 66.71  ? 339 HIS C NE2 1 
ATOM   9520  N N   . MET C 1 340 ? -39.586 6.729   77.866  1.00 67.47  ? 340 MET C N   1 
ATOM   9521  C CA  . MET C 1 340 ? -38.386 6.224   78.513  1.00 68.34  ? 340 MET C CA  1 
ATOM   9522  C C   . MET C 1 340 ? -37.836 7.310   79.431  1.00 72.98  ? 340 MET C C   1 
ATOM   9523  O O   . MET C 1 340 ? -36.679 7.718   79.283  1.00 68.98  ? 340 MET C O   1 
ATOM   9524  C CB  . MET C 1 340 ? -37.326 5.809   77.479  1.00 70.52  ? 340 MET C CB  1 
ATOM   9525  C CG  . MET C 1 340 ? -37.406 6.563   76.144  1.00 70.63  ? 340 MET C CG  1 
ATOM   9526  S SD  . MET C 1 340 ? -36.047 6.264   74.949  1.00 71.34  ? 340 MET C SD  1 
ATOM   9527  C CE  . MET C 1 340 ? -34.600 6.766   75.886  1.00 58.51  ? 340 MET C CE  1 
ATOM   9528  N N   . PRO C 1 341 ? -38.648 7.805   80.406  1.00 84.55  ? 341 PRO C N   1 
ATOM   9529  C CA  . PRO C 1 341 ? -38.193 8.856   81.320  1.00 83.94  ? 341 PRO C CA  1 
ATOM   9530  C C   . PRO C 1 341 ? -37.067 8.354   82.231  1.00 83.58  ? 341 PRO C C   1 
ATOM   9531  O O   . PRO C 1 341 ? -36.169 9.119   82.603  1.00 68.98  ? 341 PRO C O   1 
ATOM   9532  C CB  . PRO C 1 341 ? -39.472 9.253   82.090  1.00 80.49  ? 341 PRO C CB  1 
ATOM   9533  C CG  . PRO C 1 341 ? -40.376 8.027   82.018  1.00 74.80  ? 341 PRO C CG  1 
ATOM   9534  C CD  . PRO C 1 341 ? -40.025 7.357   80.707  1.00 79.43  ? 341 PRO C CD  1 
ATOM   9535  N N   . ASP C 1 342 ? -37.093 7.046   82.540  1.00 81.38  ? 342 ASP C N   1 
ATOM   9536  C CA  . ASP C 1 342 ? -36.223 6.478   83.561  1.00 81.06  ? 342 ASP C CA  1 
ATOM   9537  C C   . ASP C 1 342 ? -34.962 5.841   82.957  1.00 78.05  ? 342 ASP C C   1 
ATOM   9538  O O   . ASP C 1 342 ? -34.109 5.402   83.715  1.00 76.19  ? 342 ASP C O   1 
ATOM   9539  C CB  . ASP C 1 342 ? -36.998 5.494   84.444  1.00 83.31  ? 342 ASP C CB  1 
ATOM   9540  C CG  . ASP C 1 342 ? -38.160 6.124   85.208  1.00 90.35  ? 342 ASP C CG  1 
ATOM   9541  O OD1 . ASP C 1 342 ? -38.033 7.288   85.640  1.00 84.62  ? 342 ASP C OD1 1 
ATOM   9542  O OD2 . ASP C 1 342 ? -39.181 5.441   85.396  1.00 95.78  ? 342 ASP C OD2 1 
ATOM   9543  N N   . ASP C 1 343 ? -34.804 5.811   81.621  1.00 72.33  ? 343 ASP C N   1 
ATOM   9544  C CA  . ASP C 1 343 ? -33.585 5.293   81.007  1.00 71.31  ? 343 ASP C CA  1 
ATOM   9545  C C   . ASP C 1 343 ? -32.387 6.139   81.453  1.00 72.74  ? 343 ASP C C   1 
ATOM   9546  O O   . ASP C 1 343 ? -32.448 7.370   81.388  1.00 72.10  ? 343 ASP C O   1 
ATOM   9547  C CB  . ASP C 1 343 ? -33.719 5.220   79.478  1.00 81.85  ? 343 ASP C CB  1 
ATOM   9548  C CG  . ASP C 1 343 ? -32.459 4.860   78.684  1.00 80.29  ? 343 ASP C CG  1 
ATOM   9549  O OD1 . ASP C 1 343 ? -31.569 5.733   78.542  1.00 73.19  ? 343 ASP C OD1 1 
ATOM   9550  O OD2 . ASP C 1 343 ? -32.400 3.728   78.154  1.00 79.35  ? 343 ASP C OD2 1 
ATOM   9551  N N   . PRO C 1 344 ? -31.275 5.508   81.915  1.00 71.33  ? 344 PRO C N   1 
ATOM   9552  C CA  . PRO C 1 344 ? -30.076 6.229   82.358  1.00 70.63  ? 344 PRO C CA  1 
ATOM   9553  C C   . PRO C 1 344 ? -29.467 7.205   81.348  1.00 71.47  ? 344 PRO C C   1 
ATOM   9554  O O   . PRO C 1 344 ? -29.108 8.333   81.708  1.00 74.12  ? 344 PRO C O   1 
ATOM   9555  C CB  . PRO C 1 344 ? -29.050 5.108   82.634  1.00 72.08  ? 344 PRO C CB  1 
ATOM   9556  C CG  . PRO C 1 344 ? -29.884 3.882   82.932  1.00 74.06  ? 344 PRO C CG  1 
ATOM   9557  C CD  . PRO C 1 344 ? -31.120 4.047   82.069  1.00 75.46  ? 344 PRO C CD  1 
ATOM   9558  N N   . ILE C 1 345 ? -29.364 6.764   80.082  1.00 76.59  ? 345 ILE C N   1 
ATOM   9559  C CA  . ILE C 1 345 ? -28.670 7.498   79.026  1.00 73.68  ? 345 ILE C CA  1 
ATOM   9560  C C   . ILE C 1 345 ? -29.520 8.697   78.577  1.00 64.21  ? 345 ILE C C   1 
ATOM   9561  O O   . ILE C 1 345 ? -28.979 9.769   78.296  1.00 56.96  ? 345 ILE C O   1 
ATOM   9562  C CB  . ILE C 1 345 ? -28.277 6.554   77.858  1.00 72.08  ? 345 ILE C CB  1 
ATOM   9563  C CG1 . ILE C 1 345 ? -27.439 5.366   78.354  1.00 71.71  ? 345 ILE C CG1 1 
ATOM   9564  C CG2 . ILE C 1 345 ? -27.571 7.314   76.741  1.00 68.88  ? 345 ILE C CG2 1 
ATOM   9565  C CD1 . ILE C 1 345 ? -26.967 4.421   77.276  1.00 70.13  ? 345 ILE C CD1 1 
ATOM   9566  N N   . PHE C 1 346 ? -30.850 8.531   78.532  1.00 61.36  ? 346 PHE C N   1 
ATOM   9567  C CA  . PHE C 1 346 ? -31.737 9.653   78.274  1.00 67.63  ? 346 PHE C CA  1 
ATOM   9568  C C   . PHE C 1 346 ? -31.569 10.733  79.348  1.00 73.79  ? 346 PHE C C   1 
ATOM   9569  O O   . PHE C 1 346 ? -31.522 11.923  79.022  1.00 89.82  ? 346 PHE C O   1 
ATOM   9570  C CB  . PHE C 1 346 ? -33.211 9.243   78.191  1.00 65.91  ? 346 PHE C CB  1 
ATOM   9571  C CG  . PHE C 1 346 ? -34.142 10.432  78.120  1.00 70.04  ? 346 PHE C CG  1 
ATOM   9572  C CD1 . PHE C 1 346 ? -33.917 11.462  77.208  1.00 68.69  ? 346 PHE C CD1 1 
ATOM   9573  C CD2 . PHE C 1 346 ? -35.217 10.559  78.987  1.00 71.57  ? 346 PHE C CD2 1 
ATOM   9574  C CE1 . PHE C 1 346 ? -34.747 12.573  77.155  1.00 67.24  ? 346 PHE C CE1 1 
ATOM   9575  C CE2 . PHE C 1 346 ? -36.061 11.662  78.912  1.00 69.08  ? 346 PHE C CE2 1 
ATOM   9576  C CZ  . PHE C 1 346 ? -35.818 12.671  78.010  1.00 63.72  ? 346 PHE C CZ  1 
ATOM   9577  N N   . GLN C 1 347 ? -31.497 10.327  80.624  1.00 69.53  ? 347 GLN C N   1 
ATOM   9578  C CA  . GLN C 1 347 ? -31.381 11.271  81.724  1.00 67.02  ? 347 GLN C CA  1 
ATOM   9579  C C   . GLN C 1 347 ? -30.119 12.119  81.591  1.00 61.07  ? 347 GLN C C   1 
ATOM   9580  O O   . GLN C 1 347 ? -30.105 13.255  82.051  1.00 56.54  ? 347 GLN C O   1 
ATOM   9581  C CB  . GLN C 1 347 ? -31.373 10.556  83.076  1.00 69.91  ? 347 GLN C CB  1 
ATOM   9582  C CG  . GLN C 1 347 ? -32.751 10.124  83.553  1.00 73.24  ? 347 GLN C CG  1 
ATOM   9583  C CD  . GLN C 1 347 ? -32.685 9.262   84.791  1.00 77.15  ? 347 GLN C CD  1 
ATOM   9584  O OE1 . GLN C 1 347 ? -33.602 8.497   85.094  1.00 88.39  ? 347 GLN C OE1 1 
ATOM   9585  N NE2 . GLN C 1 347 ? -31.579 9.350   85.506  1.00 63.49  ? 347 GLN C NE2 1 
ATOM   9586  N N   . VAL C 1 348 ? -29.068 11.575  80.973  1.00 61.14  ? 348 VAL C N   1 
ATOM   9587  C CA  . VAL C 1 348 ? -27.833 12.322  80.764  1.00 68.48  ? 348 VAL C CA  1 
ATOM   9588  C C   . VAL C 1 348 ? -27.934 13.273  79.567  1.00 69.24  ? 348 VAL C C   1 
ATOM   9589  O O   . VAL C 1 348 ? -27.349 14.366  79.584  1.00 57.73  ? 348 VAL C O   1 
ATOM   9590  C CB  . VAL C 1 348 ? -26.639 11.365  80.628  1.00 67.73  ? 348 VAL C CB  1 
ATOM   9591  C CG1 . VAL C 1 348 ? -25.411 12.048  80.044  1.00 66.13  ? 348 VAL C CG1 1 
ATOM   9592  C CG2 . VAL C 1 348 ? -26.328 10.740  81.974  1.00 64.68  ? 348 VAL C CG2 1 
ATOM   9593  N N   . VAL C 1 349 ? -28.643 12.847  78.516  1.00 74.77  ? 349 VAL C N   1 
ATOM   9594  C CA  . VAL C 1 349 ? -29.001 13.735  77.418  1.00 76.37  ? 349 VAL C CA  1 
ATOM   9595  C C   . VAL C 1 349 ? -29.864 14.892  77.928  1.00 69.37  ? 349 VAL C C   1 
ATOM   9596  O O   . VAL C 1 349 ? -29.657 16.032  77.516  1.00 56.67  ? 349 VAL C O   1 
ATOM   9597  C CB  . VAL C 1 349 ? -29.738 12.960  76.313  1.00 89.53  ? 349 VAL C CB  1 
ATOM   9598  C CG1 . VAL C 1 349 ? -30.491 13.898  75.377  1.00 93.25  ? 349 VAL C CG1 1 
ATOM   9599  C CG2 . VAL C 1 349 ? -28.777 12.059  75.551  1.00 103.94 ? 349 VAL C CG2 1 
ATOM   9600  N N   . SER C 1 350 ? -30.840 14.559  78.794  1.00 68.38  ? 350 SER C N   1 
ATOM   9601  C CA  . SER C 1 350 ? -31.832 15.483  79.330  1.00 66.05  ? 350 SER C CA  1 
ATOM   9602  C C   . SER C 1 350 ? -31.171 16.628  80.109  1.00 70.27  ? 350 SER C C   1 
ATOM   9603  O O   . SER C 1 350 ? -31.456 17.808  79.881  1.00 61.64  ? 350 SER C O   1 
ATOM   9604  C CB  . SER C 1 350 ? -32.782 14.710  80.200  1.00 64.27  ? 350 SER C CB  1 
ATOM   9605  O OG  . SER C 1 350 ? -33.893 15.496  80.561  1.00 69.02  ? 350 SER C OG  1 
ATOM   9606  N N   . MET C 1 351 ? -30.284 16.248  81.034  1.00 67.76  ? 351 MET C N   1 
ATOM   9607  C CA  . MET C 1 351 ? -29.475 17.183  81.796  1.00 75.06  ? 351 MET C CA  1 
ATOM   9608  C C   . MET C 1 351 ? -28.541 17.986  80.895  1.00 68.95  ? 351 MET C C   1 
ATOM   9609  O O   . MET C 1 351 ? -28.380 19.178  81.126  1.00 74.73  ? 351 MET C O   1 
ATOM   9610  C CB  . MET C 1 351 ? -28.622 16.446  82.832  1.00 84.45  ? 351 MET C CB  1 
ATOM   9611  C CG  . MET C 1 351 ? -29.295 16.280  84.186  1.00 89.97  ? 351 MET C CG  1 
ATOM   9612  S SD  . MET C 1 351 ? -28.514 14.927  85.094  1.00 99.54  ? 351 MET C SD  1 
ATOM   9613  C CE  . MET C 1 351 ? -26.874 15.616  85.302  1.00 101.31 ? 351 MET C CE  1 
ATOM   9614  N N   . LEU C 1 352 ? -27.899 17.353  79.900  1.00 64.07  ? 352 LEU C N   1 
ATOM   9615  C CA  . LEU C 1 352 ? -27.006 18.080  78.998  1.00 65.67  ? 352 LEU C CA  1 
ATOM   9616  C C   . LEU C 1 352 ? -27.732 19.247  78.315  1.00 67.57  ? 352 LEU C C   1 
ATOM   9617  O O   . LEU C 1 352 ? -27.112 20.281  78.063  1.00 60.17  ? 352 LEU C O   1 
ATOM   9618  C CB  . LEU C 1 352 ? -26.442 17.140  77.926  1.00 61.89  ? 352 LEU C CB  1 
ATOM   9619  C CG  . LEU C 1 352 ? -25.245 16.287  78.320  1.00 63.51  ? 352 LEU C CG  1 
ATOM   9620  C CD1 . LEU C 1 352 ? -24.903 15.329  77.194  1.00 57.74  ? 352 LEU C CD1 1 
ATOM   9621  C CD2 . LEU C 1 352 ? -24.035 17.136  78.660  1.00 66.66  ? 352 LEU C CD2 1 
ATOM   9622  N N   . TYR C 1 353 ? -29.018 19.049  77.969  1.00 66.61  ? 353 TYR C N   1 
ATOM   9623  C CA  . TYR C 1 353 ? -29.851 20.078  77.371  1.00 72.66  ? 353 TYR C CA  1 
ATOM   9624  C C   . TYR C 1 353 ? -29.851 21.338  78.245  1.00 88.35  ? 353 TYR C C   1 
ATOM   9625  O O   . TYR C 1 353 ? -29.786 22.458  77.732  1.00 89.04  ? 353 TYR C O   1 
ATOM   9626  C CB  . TYR C 1 353 ? -31.287 19.571  77.205  1.00 71.13  ? 353 TYR C CB  1 
ATOM   9627  C CG  . TYR C 1 353 ? -32.195 20.434  76.360  1.00 70.14  ? 353 TYR C CG  1 
ATOM   9628  C CD1 . TYR C 1 353 ? -31.682 21.265  75.370  1.00 70.60  ? 353 TYR C CD1 1 
ATOM   9629  C CD2 . TYR C 1 353 ? -33.577 20.418  76.543  1.00 63.14  ? 353 TYR C CD2 1 
ATOM   9630  C CE1 . TYR C 1 353 ? -32.510 22.059  74.590  1.00 78.44  ? 353 TYR C CE1 1 
ATOM   9631  C CE2 . TYR C 1 353 ? -34.417 21.207  75.772  1.00 67.56  ? 353 TYR C CE2 1 
ATOM   9632  C CZ  . TYR C 1 353 ? -33.882 22.030  74.789  1.00 78.40  ? 353 TYR C CZ  1 
ATOM   9633  O OH  . TYR C 1 353 ? -34.675 22.818  73.981  1.00 78.94  ? 353 TYR C OH  1 
ATOM   9634  N N   . GLU C 1 354 ? -29.923 21.139  79.572  1.00 93.66  ? 354 GLU C N   1 
ATOM   9635  C CA  . GLU C 1 354 ? -30.006 22.221  80.545  1.00 85.53  ? 354 GLU C CA  1 
ATOM   9636  C C   . GLU C 1 354 ? -28.658 22.938  80.650  1.00 80.91  ? 354 GLU C C   1 
ATOM   9637  O O   . GLU C 1 354 ? -28.573 24.163  80.527  1.00 82.99  ? 354 GLU C O   1 
ATOM   9638  C CB  . GLU C 1 354 ? -30.421 21.646  81.901  1.00 85.10  ? 354 GLU C CB  1 
ATOM   9639  C CG  . GLU C 1 354 ? -31.412 22.502  82.652  1.00 94.59  ? 354 GLU C CG  1 
ATOM   9640  C CD  . GLU C 1 354 ? -32.135 21.761  83.761  1.00 103.80 ? 354 GLU C CD  1 
ATOM   9641  O OE1 . GLU C 1 354 ? -31.979 22.175  84.924  1.00 115.09 ? 354 GLU C OE1 1 
ATOM   9642  O OE2 . GLU C 1 354 ? -32.867 20.779  83.463  1.00 101.55 ? 354 GLU C OE2 1 
ATOM   9643  N N   . VAL C 1 355 ? -27.604 22.141  80.834  1.00 77.78  ? 355 VAL C N   1 
ATOM   9644  C CA  . VAL C 1 355 ? -26.341 22.632  81.351  1.00 82.65  ? 355 VAL C CA  1 
ATOM   9645  C C   . VAL C 1 355 ? -25.409 23.105  80.224  1.00 85.96  ? 355 VAL C C   1 
ATOM   9646  O O   . VAL C 1 355 ? -24.585 23.985  80.450  1.00 91.12  ? 355 VAL C O   1 
ATOM   9647  C CB  . VAL C 1 355 ? -25.709 21.550  82.249  1.00 87.88  ? 355 VAL C CB  1 
ATOM   9648  C CG1 . VAL C 1 355 ? -24.697 20.686  81.508  1.00 90.66  ? 355 VAL C CG1 1 
ATOM   9649  C CG2 . VAL C 1 355 ? -25.088 22.163  83.493  1.00 100.92 ? 355 VAL C CG2 1 
ATOM   9650  N N   . VAL C 1 356 ? -25.531 22.553  79.006  1.00 83.45  ? 356 VAL C N   1 
ATOM   9651  C CA  . VAL C 1 356 ? -24.519 22.759  77.971  1.00 83.74  ? 356 VAL C CA  1 
ATOM   9652  C C   . VAL C 1 356 ? -24.713 24.085  77.230  1.00 80.94  ? 356 VAL C C   1 
ATOM   9653  O O   . VAL C 1 356 ? -23.717 24.697  76.829  1.00 74.09  ? 356 VAL C O   1 
ATOM   9654  C CB  . VAL C 1 356 ? -24.454 21.591  76.964  1.00 84.28  ? 356 VAL C CB  1 
ATOM   9655  C CG1 . VAL C 1 356 ? -23.350 21.803  75.940  1.00 79.35  ? 356 VAL C CG1 1 
ATOM   9656  C CG2 . VAL C 1 356 ? -24.277 20.241  77.642  1.00 89.76  ? 356 VAL C CG2 1 
ATOM   9657  N N   . PRO C 1 357 ? -25.957 24.542  76.923  1.00 86.76  ? 357 PRO C N   1 
ATOM   9658  C CA  . PRO C 1 357 ? -26.150 25.855  76.294  1.00 90.45  ? 357 PRO C CA  1 
ATOM   9659  C C   . PRO C 1 357 ? -25.701 27.070  77.117  1.00 87.55  ? 357 PRO C C   1 
ATOM   9660  O O   . PRO C 1 357 ? -25.064 27.951  76.538  1.00 88.24  ? 357 PRO C O   1 
ATOM   9661  C CB  . PRO C 1 357 ? -27.653 25.908  75.956  1.00 86.85  ? 357 PRO C CB  1 
ATOM   9662  C CG  . PRO C 1 357 ? -28.086 24.450  75.964  1.00 84.69  ? 357 PRO C CG  1 
ATOM   9663  C CD  . PRO C 1 357 ? -27.222 23.796  77.024  1.00 83.78  ? 357 PRO C CD  1 
ATOM   9664  N N   . PRO C 1 358 ? -26.000 27.201  78.446  1.00 86.99  ? 358 PRO C N   1 
ATOM   9665  C CA  . PRO C 1 358 ? -25.350 28.222  79.284  1.00 82.43  ? 358 PRO C CA  1 
ATOM   9666  C C   . PRO C 1 358 ? -23.825 28.337  79.133  1.00 75.46  ? 358 PRO C C   1 
ATOM   9667  O O   . PRO C 1 358 ? -23.296 29.443  79.078  1.00 69.81  ? 358 PRO C O   1 
ATOM   9668  C CB  . PRO C 1 358 ? -25.755 27.804  80.715  1.00 75.14  ? 358 PRO C CB  1 
ATOM   9669  C CG  . PRO C 1 358 ? -27.126 27.179  80.540  1.00 76.52  ? 358 PRO C CG  1 
ATOM   9670  C CD  . PRO C 1 358 ? -27.031 26.458  79.204  1.00 83.31  ? 358 PRO C CD  1 
ATOM   9671  N N   . ILE C 1 359 ? -23.142 27.192  78.998  1.00 83.39  ? 359 ILE C N   1 
ATOM   9672  C CA  . ILE C 1 359 ? -21.687 27.089  79.042  1.00 88.65  ? 359 ILE C CA  1 
ATOM   9673  C C   . ILE C 1 359 ? -21.039 27.396  77.682  1.00 95.80  ? 359 ILE C C   1 
ATOM   9674  O O   . ILE C 1 359 ? -19.968 28.009  77.643  1.00 94.47  ? 359 ILE C O   1 
ATOM   9675  C CB  . ILE C 1 359 ? -21.292 25.692  79.570  1.00 85.48  ? 359 ILE C CB  1 
ATOM   9676  C CG1 . ILE C 1 359 ? -21.764 25.498  81.012  1.00 87.34  ? 359 ILE C CG1 1 
ATOM   9677  C CG2 . ILE C 1 359 ? -19.795 25.440  79.426  1.00 90.07  ? 359 ILE C CG2 1 
ATOM   9678  C CD1 . ILE C 1 359 ? -21.554 24.096  81.543  1.00 90.96  ? 359 ILE C CD1 1 
ATOM   9679  N N   . LEU C 1 360 ? -21.655 26.954  76.572  1.00 95.83  ? 360 LEU C N   1 
ATOM   9680  C CA  . LEU C 1 360 ? -21.170 27.294  75.238  1.00 95.04  ? 360 LEU C CA  1 
ATOM   9681  C C   . LEU C 1 360 ? -21.521 28.754  74.906  1.00 86.90  ? 360 LEU C C   1 
ATOM   9682  O O   . LEU C 1 360 ? -21.064 29.300  73.901  1.00 68.27  ? 360 LEU C O   1 
ATOM   9683  C CB  . LEU C 1 360 ? -21.781 26.318  74.219  1.00 96.47  ? 360 LEU C CB  1 
ATOM   9684  C CG  . LEU C 1 360 ? -21.379 24.843  74.330  1.00 87.47  ? 360 LEU C CG  1 
ATOM   9685  C CD1 . LEU C 1 360 ? -22.344 23.958  73.554  1.00 89.84  ? 360 LEU C CD1 1 
ATOM   9686  C CD2 . LEU C 1 360 ? -19.964 24.620  73.818  1.00 78.27  ? 360 LEU C CD2 1 
ATOM   9687  N N   . SER C 1 361 ? -22.337 29.378  75.771  1.00 91.88  ? 361 SER C N   1 
ATOM   9688  C CA  . SER C 1 361 ? -22.760 30.764  75.636  1.00 88.32  ? 361 SER C CA  1 
ATOM   9689  C C   . SER C 1 361 ? -21.718 31.722  76.230  1.00 94.03  ? 361 SER C C   1 
ATOM   9690  O O   . SER C 1 361 ? -21.383 32.732  75.607  1.00 86.60  ? 361 SER C O   1 
ATOM   9691  C CB  . SER C 1 361 ? -24.104 30.947  76.290  1.00 84.43  ? 361 SER C CB  1 
ATOM   9692  O OG  . SER C 1 361 ? -24.949 31.718  75.460  1.00 86.65  ? 361 SER C OG  1 
ATOM   9693  N N   . SER C 1 362 ? -21.232 31.396  77.445  1.00 96.50  ? 362 SER C N   1 
ATOM   9694  C CA  . SER C 1 362 ? -20.125 32.081  78.106  1.00 98.67  ? 362 SER C CA  1 
ATOM   9695  C C   . SER C 1 362 ? -18.937 32.289  77.166  1.00 108.16 ? 362 SER C C   1 
ATOM   9696  O O   . SER C 1 362 ? -18.300 33.335  77.210  1.00 116.27 ? 362 SER C O   1 
ATOM   9697  C CB  . SER C 1 362 ? -19.661 31.323  79.325  1.00 94.38  ? 362 SER C CB  1 
ATOM   9698  O OG  . SER C 1 362 ? -20.678 31.323  80.312  1.00 105.37 ? 362 SER C OG  1 
ATOM   9699  N N   . LEU C 1 363 ? -18.616 31.263  76.365  1.00 114.49 ? 363 LEU C N   1 
ATOM   9700  C CA  . LEU C 1 363 ? -17.424 31.266  75.530  1.00 110.34 ? 363 LEU C CA  1 
ATOM   9701  C C   . LEU C 1 363 ? -17.665 32.054  74.237  1.00 113.46 ? 363 LEU C C   1 
ATOM   9702  O O   . LEU C 1 363 ? -16.695 32.432  73.579  1.00 108.84 ? 363 LEU C O   1 
ATOM   9703  C CB  . LEU C 1 363 ? -17.006 29.816  75.238  1.00 119.96 ? 363 LEU C CB  1 
ATOM   9704  C CG  . LEU C 1 363 ? -16.872 28.868  76.441  1.00 122.20 ? 363 LEU C CG  1 
ATOM   9705  C CD1 . LEU C 1 363 ? -16.018 27.655  76.087  1.00 123.52 ? 363 LEU C CD1 1 
ATOM   9706  C CD2 . LEU C 1 363 ? -16.316 29.566  77.681  1.00 112.02 ? 363 LEU C CD2 1 
ATOM   9707  N N   . GLY C 1 364 ? -18.942 32.288  73.864  1.00 115.77 ? 364 GLY C N   1 
ATOM   9708  C CA  . GLY C 1 364 ? -19.295 33.080  72.686  1.00 107.50 ? 364 GLY C CA  1 
ATOM   9709  C C   . GLY C 1 364 ? -18.502 32.661  71.445  1.00 111.66 ? 364 GLY C C   1 
ATOM   9710  O O   . GLY C 1 364 ? -18.200 33.481  70.581  1.00 103.30 ? 364 GLY C O   1 
ATOM   9711  N N   . LYS C 1 365 ? -18.221 31.354  71.356  1.00 123.28 ? 365 LYS C N   1 
ATOM   9712  C CA  . LYS C 1 365 ? -17.176 30.781  70.522  1.00 118.77 ? 365 LYS C CA  1 
ATOM   9713  C C   . LYS C 1 365 ? -17.798 30.129  69.287  1.00 123.63 ? 365 LYS C C   1 
ATOM   9714  O O   . LYS C 1 365 ? -17.525 30.564  68.166  1.00 119.22 ? 365 LYS C O   1 
ATOM   9715  C CB  . LYS C 1 365 ? -16.410 29.751  71.364  1.00 121.41 ? 365 LYS C CB  1 
ATOM   9716  C CG  . LYS C 1 365 ? -15.132 29.184  70.766  1.00 115.70 ? 365 LYS C CG  1 
ATOM   9717  C CD  . LYS C 1 365 ? -13.883 29.657  71.486  1.00 116.16 ? 365 LYS C CD  1 
ATOM   9718  C CE  . LYS C 1 365 ? -12.704 28.737  71.274  1.00 117.06 ? 365 LYS C CE  1 
ATOM   9719  N NZ  . LYS C 1 365 ? -11.526 29.228  72.022  1.00 116.62 ? 365 LYS C NZ  1 
ATOM   9720  N N   . VAL C 1 366 ? -18.634 29.099  69.526  1.00 131.52 ? 366 VAL C N   1 
ATOM   9721  C CA  . VAL C 1 366 ? -19.278 28.298  68.490  1.00 129.89 ? 366 VAL C CA  1 
ATOM   9722  C C   . VAL C 1 366 ? -20.584 28.982  68.065  1.00 126.37 ? 366 VAL C C   1 
ATOM   9723  O O   . VAL C 1 366 ? -21.319 29.491  68.913  1.00 123.62 ? 366 VAL C O   1 
ATOM   9724  C CB  . VAL C 1 366 ? -19.516 26.843  68.969  1.00 122.35 ? 366 VAL C CB  1 
ATOM   9725  C CG1 . VAL C 1 366 ? -18.226 26.156  69.414  1.00 113.04 ? 366 VAL C CG1 1 
ATOM   9726  C CG2 . VAL C 1 366 ? -20.565 26.742  70.071  1.00 112.49 ? 366 VAL C CG2 1 
ATOM   9727  N N   . LYS C 1 367 ? -20.879 28.973  66.755  1.00 106.52 ? 367 LYS C N   1 
ATOM   9728  C CA  . LYS C 1 367 ? -21.928 29.816  66.191  1.00 90.50  ? 367 LYS C CA  1 
ATOM   9729  C C   . LYS C 1 367 ? -23.329 29.251  66.493  1.00 91.02  ? 367 LYS C C   1 
ATOM   9730  O O   . LYS C 1 367 ? -24.329 29.932  66.251  1.00 81.95  ? 367 LYS C O   1 
ATOM   9731  C CB  . LYS C 1 367 ? -21.682 30.030  64.688  1.00 76.31  ? 367 LYS C CB  1 
ATOM   9732  N N   . ASP C 1 368 ? -23.415 28.013  67.025  1.00 91.69  ? 368 ASP C N   1 
ATOM   9733  C CA  . ASP C 1 368 ? -24.677 27.384  67.425  1.00 93.85  ? 368 ASP C CA  1 
ATOM   9734  C C   . ASP C 1 368 ? -24.489 26.756  68.807  1.00 98.44  ? 368 ASP C C   1 
ATOM   9735  O O   . ASP C 1 368 ? -24.014 25.627  68.904  1.00 112.35 ? 368 ASP C O   1 
ATOM   9736  C CB  . ASP C 1 368 ? -25.163 26.352  66.387  1.00 87.92  ? 368 ASP C CB  1 
ATOM   9737  C CG  . ASP C 1 368 ? -26.440 25.574  66.713  1.00 75.15  ? 368 ASP C CG  1 
ATOM   9738  O OD1 . ASP C 1 368 ? -27.342 26.149  67.363  1.00 72.86  ? 368 ASP C OD1 1 
ATOM   9739  O OD2 . ASP C 1 368 ? -26.562 24.408  66.257  1.00 60.81  ? 368 ASP C OD2 1 
ATOM   9740  N N   . PRO C 1 369 ? -24.845 27.461  69.913  1.00 94.94  ? 369 PRO C N   1 
ATOM   9741  C CA  . PRO C 1 369 ? -24.630 26.948  71.274  1.00 92.72  ? 369 PRO C CA  1 
ATOM   9742  C C   . PRO C 1 369 ? -25.717 25.999  71.786  1.00 90.09  ? 369 PRO C C   1 
ATOM   9743  O O   . PRO C 1 369 ? -26.019 25.975  72.977  1.00 79.37  ? 369 PRO C O   1 
ATOM   9744  C CB  . PRO C 1 369 ? -24.607 28.246  72.103  1.00 92.99  ? 369 PRO C CB  1 
ATOM   9745  C CG  . PRO C 1 369 ? -25.578 29.160  71.383  1.00 91.83  ? 369 PRO C CG  1 
ATOM   9746  C CD  . PRO C 1 369 ? -25.440 28.809  69.913  1.00 90.20  ? 369 PRO C CD  1 
ATOM   9747  N N   . TRP C 1 370 ? -26.262 25.186  70.871  1.00 88.43  ? 370 TRP C N   1 
ATOM   9748  C CA  . TRP C 1 370 ? -27.518 24.484  71.075  1.00 74.72  ? 370 TRP C CA  1 
ATOM   9749  C C   . TRP C 1 370 ? -27.431 23.103  70.432  1.00 63.16  ? 370 TRP C C   1 
ATOM   9750  O O   . TRP C 1 370 ? -26.528 22.851  69.626  1.00 55.37  ? 370 TRP C O   1 
ATOM   9751  C CB  . TRP C 1 370 ? -28.686 25.313  70.511  1.00 77.82  ? 370 TRP C CB  1 
ATOM   9752  C CG  . TRP C 1 370 ? -28.986 26.569  71.279  1.00 82.82  ? 370 TRP C CG  1 
ATOM   9753  C CD1 . TRP C 1 370 ? -28.637 27.842  70.935  1.00 81.34  ? 370 TRP C CD1 1 
ATOM   9754  C CD2 . TRP C 1 370 ? -29.719 26.681  72.514  1.00 85.10  ? 370 TRP C CD2 1 
ATOM   9755  N NE1 . TRP C 1 370 ? -29.083 28.734  71.870  1.00 83.14  ? 370 TRP C NE1 1 
ATOM   9756  C CE2 . TRP C 1 370 ? -29.750 28.050  72.852  1.00 83.11  ? 370 TRP C CE2 1 
ATOM   9757  C CE3 . TRP C 1 370 ? -30.337 25.763  73.371  1.00 91.92  ? 370 TRP C CE3 1 
ATOM   9758  C CZ2 . TRP C 1 370 ? -30.378 28.515  74.006  1.00 83.52  ? 370 TRP C CZ2 1 
ATOM   9759  C CZ3 . TRP C 1 370 ? -30.963 26.227  74.507  1.00 90.82  ? 370 TRP C CZ3 1 
ATOM   9760  C CH2 . TRP C 1 370 ? -30.985 27.585  74.817  1.00 84.91  ? 370 TRP C CH2 1 
ATOM   9761  N N   . PRO C 1 371 ? -28.340 22.165  70.806  1.00 60.98  ? 371 PRO C N   1 
ATOM   9762  C CA  . PRO C 1 371 ? -28.365 20.821  70.217  1.00 65.31  ? 371 PRO C CA  1 
ATOM   9763  C C   . PRO C 1 371 ? -28.971 20.698  68.818  1.00 67.11  ? 371 PRO C C   1 
ATOM   9764  O O   . PRO C 1 371 ? -29.859 21.481  68.453  1.00 69.79  ? 371 PRO C O   1 
ATOM   9765  C CB  . PRO C 1 371 ? -29.237 20.020  71.205  1.00 65.56  ? 371 PRO C CB  1 
ATOM   9766  C CG  . PRO C 1 371 ? -30.162 21.041  71.824  1.00 63.15  ? 371 PRO C CG  1 
ATOM   9767  C CD  . PRO C 1 371 ? -29.349 22.321  71.870  1.00 62.78  ? 371 PRO C CD  1 
ATOM   9768  N N   . ASN C 1 372 ? -28.453 19.707  68.058  1.00 70.25  ? 372 ASN C N   1 
ATOM   9769  C CA  . ASN C 1 372 ? -29.086 19.194  66.843  1.00 71.63  ? 372 ASN C CA  1 
ATOM   9770  C C   . ASN C 1 372 ? -29.622 17.781  67.128  1.00 77.68  ? 372 ASN C C   1 
ATOM   9771  O O   . ASN C 1 372 ? -29.552 17.317  68.267  1.00 75.52  ? 372 ASN C O   1 
ATOM   9772  C CB  . ASN C 1 372 ? -28.167 19.348  65.616  1.00 65.68  ? 372 ASN C CB  1 
ATOM   9773  C CG  . ASN C 1 372 ? -26.881 18.553  65.664  1.00 68.30  ? 372 ASN C CG  1 
ATOM   9774  O OD1 . ASN C 1 372 ? -26.882 17.351  65.409  1.00 66.18  ? 372 ASN C OD1 1 
ATOM   9775  N ND2 . ASN C 1 372 ? -25.775 19.226  65.930  1.00 64.12  ? 372 ASN C ND2 1 
ATOM   9776  N N   . VAL C 1 373 ? -30.213 17.117  66.113  1.00 73.63  ? 373 VAL C N   1 
ATOM   9777  C CA  . VAL C 1 373 ? -30.885 15.832  66.302  1.00 63.68  ? 373 VAL C CA  1 
ATOM   9778  C C   . VAL C 1 373 ? -29.955 14.756  66.860  1.00 63.44  ? 373 VAL C C   1 
ATOM   9779  O O   . VAL C 1 373 ? -30.413 13.921  67.642  1.00 57.05  ? 373 VAL C O   1 
ATOM   9780  C CB  . VAL C 1 373 ? -31.488 15.246  65.017  1.00 61.35  ? 373 VAL C CB  1 
ATOM   9781  C CG1 . VAL C 1 373 ? -32.984 15.072  65.147  1.00 59.62  ? 373 VAL C CG1 1 
ATOM   9782  C CG2 . VAL C 1 373 ? -31.066 15.966  63.748  1.00 62.83  ? 373 VAL C CG2 1 
ATOM   9783  N N   . ASP C 1 374 ? -28.696 14.747  66.390  1.00 56.24  ? 374 ASP C N   1 
ATOM   9784  C CA  . ASP C 1 374 ? -27.753 13.675  66.659  1.00 66.51  ? 374 ASP C CA  1 
ATOM   9785  C C   . ASP C 1 374 ? -27.495 13.528  68.156  1.00 61.38  ? 374 ASP C C   1 
ATOM   9786  O O   . ASP C 1 374 ? -27.113 12.449  68.613  1.00 63.13  ? 374 ASP C O   1 
ATOM   9787  C CB  . ASP C 1 374 ? -26.470 13.891  65.857  1.00 79.21  ? 374 ASP C CB  1 
ATOM   9788  C CG  . ASP C 1 374 ? -26.724 14.002  64.357  1.00 92.82  ? 374 ASP C CG  1 
ATOM   9789  O OD1 . ASP C 1 374 ? -27.369 13.092  63.799  1.00 100.54 ? 374 ASP C OD1 1 
ATOM   9790  O OD2 . ASP C 1 374 ? -26.266 14.994  63.749  1.00 96.43  ? 374 ASP C OD2 1 
ATOM   9791  N N   . ALA C 1 375 ? -27.756 14.603  68.905  1.00 64.35  ? 375 ALA C N   1 
ATOM   9792  C CA  . ALA C 1 375 ? -27.694 14.597  70.359  1.00 68.45  ? 375 ALA C CA  1 
ATOM   9793  C C   . ALA C 1 375 ? -28.729 13.654  70.980  1.00 66.09  ? 375 ALA C C   1 
ATOM   9794  O O   . ALA C 1 375 ? -28.493 13.148  72.080  1.00 68.64  ? 375 ALA C O   1 
ATOM   9795  C CB  . ALA C 1 375 ? -27.859 16.007  70.887  1.00 68.74  ? 375 ALA C CB  1 
ATOM   9796  N N   . HIS C 1 376 ? -29.852 13.396  70.289  1.00 59.70  ? 376 HIS C N   1 
ATOM   9797  C CA  . HIS C 1 376 ? -30.970 12.695  70.913  1.00 57.53  ? 376 HIS C CA  1 
ATOM   9798  C C   . HIS C 1 376 ? -31.353 11.376  70.220  1.00 60.27  ? 376 HIS C C   1 
ATOM   9799  O O   . HIS C 1 376 ? -32.133 10.604  70.775  1.00 59.65  ? 376 HIS C O   1 
ATOM   9800  C CB  . HIS C 1 376 ? -32.170 13.637  70.962  1.00 58.39  ? 376 HIS C CB  1 
ATOM   9801  C CG  . HIS C 1 376 ? -33.014 13.482  72.190  1.00 58.73  ? 376 HIS C CG  1 
ATOM   9802  N ND1 . HIS C 1 376 ? -33.454 12.276  72.672  1.00 56.98  ? 376 HIS C ND1 1 
ATOM   9803  C CD2 . HIS C 1 376 ? -33.450 14.441  73.057  1.00 62.13  ? 376 HIS C CD2 1 
ATOM   9804  C CE1 . HIS C 1 376 ? -34.147 12.478  73.792  1.00 60.10  ? 376 HIS C CE1 1 
ATOM   9805  N NE2 . HIS C 1 376 ? -34.153 13.817  74.050  1.00 62.97  ? 376 HIS C NE2 1 
ATOM   9806  N N   . SER C 1 377 ? -30.826 11.105  69.018  1.00 61.16  ? 377 SER C N   1 
ATOM   9807  C CA  . SER C 1 377 ? -31.281 9.975   68.209  1.00 61.07  ? 377 SER C CA  1 
ATOM   9808  C C   . SER C 1 377 ? -30.872 8.630   68.821  1.00 56.95  ? 377 SER C C   1 
ATOM   9809  O O   . SER C 1 377 ? -31.702 7.725   68.988  1.00 46.40  ? 377 SER C O   1 
ATOM   9810  C CB  . SER C 1 377 ? -30.769 10.092  66.781  1.00 60.34  ? 377 SER C CB  1 
ATOM   9811  O OG  . SER C 1 377 ? -31.361 11.178  66.090  1.00 58.43  ? 377 SER C OG  1 
ATOM   9812  N N   . GLY C 1 378 ? -29.577 8.523   69.147  1.00 56.69  ? 378 GLY C N   1 
ATOM   9813  C CA  . GLY C 1 378 ? -28.931 7.259   69.445  1.00 54.78  ? 378 GLY C CA  1 
ATOM   9814  C C   . GLY C 1 378 ? -29.450 6.628   70.729  1.00 51.29  ? 378 GLY C C   1 
ATOM   9815  O O   . GLY C 1 378 ? -29.556 5.403   70.818  1.00 44.66  ? 378 GLY C O   1 
ATOM   9816  N N   . CYS C 1 379 ? -29.783 7.478   71.708  1.00 55.04  ? 379 CYS C N   1 
ATOM   9817  C CA  . CYS C 1 379 ? -30.194 6.980   73.010  1.00 55.74  ? 379 CYS C CA  1 
ATOM   9818  C C   . CYS C 1 379 ? -31.540 6.255   72.908  1.00 53.58  ? 379 CYS C C   1 
ATOM   9819  O O   . CYS C 1 379 ? -31.803 5.298   73.648  1.00 56.76  ? 379 CYS C O   1 
ATOM   9820  C CB  . CYS C 1 379 ? -30.172 8.085   74.063  1.00 59.87  ? 379 CYS C CB  1 
ATOM   9821  S SG  . CYS C 1 379 ? -31.484 9.323   73.916  1.00 66.84  ? 379 CYS C SG  1 
ATOM   9822  N N   . ILE C 1 380 ? -32.368 6.669   71.944  1.00 49.33  ? 380 ILE C N   1 
ATOM   9823  C CA  . ILE C 1 380 ? -33.674 6.070   71.753  1.00 42.51  ? 380 ILE C CA  1 
ATOM   9824  C C   . ILE C 1 380 ? -33.518 4.708   71.076  1.00 42.16  ? 380 ILE C C   1 
ATOM   9825  O O   . ILE C 1 380 ? -34.184 3.750   71.450  1.00 43.10  ? 380 ILE C O   1 
ATOM   9826  C CB  . ILE C 1 380 ? -34.555 7.027   70.932  1.00 39.01  ? 380 ILE C CB  1 
ATOM   9827  C CG1 . ILE C 1 380 ? -34.809 8.336   71.673  1.00 40.59  ? 380 ILE C CG1 1 
ATOM   9828  C CG2 . ILE C 1 380 ? -35.846 6.332   70.514  1.00 43.21  ? 380 ILE C CG2 1 
ATOM   9829  C CD1 . ILE C 1 380 ? -35.639 9.338   70.890  1.00 41.19  ? 380 ILE C CD1 1 
ATOM   9830  N N   . GLN C 1 381 ? -32.661 4.654   70.042  1.00 43.44  ? 381 GLN C N   1 
ATOM   9831  C CA  . GLN C 1 381 ? -32.346 3.417   69.344  1.00 41.81  ? 381 GLN C CA  1 
ATOM   9832  C C   . GLN C 1 381 ? -31.766 2.431   70.356  1.00 41.19  ? 381 GLN C C   1 
ATOM   9833  O O   . GLN C 1 381 ? -32.203 1.287   70.453  1.00 41.07  ? 381 GLN C O   1 
ATOM   9834  C CB  . GLN C 1 381 ? -31.316 3.654   68.226  1.00 42.13  ? 381 GLN C CB  1 
ATOM   9835  C CG  . GLN C 1 381 ? -31.778 4.553   67.070  1.00 41.94  ? 381 GLN C CG  1 
ATOM   9836  C CD  . GLN C 1 381 ? -33.070 4.079   66.446  1.00 41.54  ? 381 GLN C CD  1 
ATOM   9837  O OE1 . GLN C 1 381 ? -33.969 4.873   66.180  1.00 45.52  ? 381 GLN C OE1 1 
ATOM   9838  N NE2 . GLN C 1 381 ? -33.176 2.783   66.201  1.00 30.02  ? 381 GLN C NE2 1 
ATOM   9839  N N   . TRP C 1 382 ? -30.761 2.894   71.102  1.00 36.85  ? 382 TRP C N   1 
ATOM   9840  C CA  . TRP C 1 382 ? -30.108 2.066   72.089  1.00 40.13  ? 382 TRP C CA  1 
ATOM   9841  C C   . TRP C 1 382 ? -31.132 1.440   73.032  1.00 42.25  ? 382 TRP C C   1 
ATOM   9842  O O   . TRP C 1 382 ? -31.054 0.244   73.304  1.00 38.85  ? 382 TRP C O   1 
ATOM   9843  C CB  . TRP C 1 382 ? -29.083 2.881   72.870  1.00 42.02  ? 382 TRP C CB  1 
ATOM   9844  C CG  . TRP C 1 382 ? -28.264 2.013   73.767  1.00 43.15  ? 382 TRP C CG  1 
ATOM   9845  C CD1 . TRP C 1 382 ? -28.555 1.612   75.042  1.00 42.04  ? 382 TRP C CD1 1 
ATOM   9846  C CD2 . TRP C 1 382 ? -27.040 1.358   73.402  1.00 48.33  ? 382 TRP C CD2 1 
ATOM   9847  N NE1 . TRP C 1 382 ? -27.579 0.774   75.511  1.00 45.24  ? 382 TRP C NE1 1 
ATOM   9848  C CE2 . TRP C 1 382 ? -26.627 0.612   74.533  1.00 51.49  ? 382 TRP C CE2 1 
ATOM   9849  C CE3 . TRP C 1 382 ? -26.243 1.349   72.250  1.00 49.58  ? 382 TRP C CE3 1 
ATOM   9850  C CZ2 . TRP C 1 382 ? -25.439 -0.128  74.538  1.00 49.73  ? 382 TRP C CZ2 1 
ATOM   9851  C CZ3 . TRP C 1 382 ? -25.080 0.606   72.261  1.00 53.02  ? 382 TRP C CZ3 1 
ATOM   9852  C CH2 . TRP C 1 382 ? -24.681 -0.115  73.391  1.00 46.32  ? 382 TRP C CH2 1 
ATOM   9853  N N   . HIS C 1 383 ? -32.070 2.256   73.536  1.00 42.08  ? 383 HIS C N   1 
ATOM   9854  C CA  . HIS C 1 383 ? -33.034 1.779   74.507  1.00 46.89  ? 383 HIS C CA  1 
ATOM   9855  C C   . HIS C 1 383 ? -33.854 0.618   73.943  1.00 45.94  ? 383 HIS C C   1 
ATOM   9856  O O   . HIS C 1 383 ? -34.260 -0.256  74.705  1.00 48.75  ? 383 HIS C O   1 
ATOM   9857  C CB  . HIS C 1 383 ? -33.958 2.904   74.991  1.00 53.97  ? 383 HIS C CB  1 
ATOM   9858  C CG  . HIS C 1 383 ? -35.090 2.459   75.889  1.00 58.62  ? 383 HIS C CG  1 
ATOM   9859  N ND1 . HIS C 1 383 ? -35.032 2.475   77.273  1.00 53.50  ? 383 HIS C ND1 1 
ATOM   9860  C CD2 . HIS C 1 383 ? -36.310 1.929   75.549  1.00 53.52  ? 383 HIS C CD2 1 
ATOM   9861  C CE1 . HIS C 1 383 ? -36.175 1.991   77.761  1.00 59.36  ? 383 HIS C CE1 1 
ATOM   9862  N NE2 . HIS C 1 383 ? -36.984 1.638   76.707  1.00 57.78  ? 383 HIS C NE2 1 
ATOM   9863  N N   . TYR C 1 384 ? -34.092 0.584   72.629  1.00 47.37  ? 384 TYR C N   1 
ATOM   9864  C CA  . TYR C 1 384 ? -34.903 -0.485  72.046  1.00 54.44  ? 384 TYR C CA  1 
ATOM   9865  C C   . TYR C 1 384 ? -34.053 -1.616  71.461  1.00 47.97  ? 384 TYR C C   1 
ATOM   9866  O O   . TYR C 1 384 ? -34.583 -2.470  70.755  1.00 56.36  ? 384 TYR C O   1 
ATOM   9867  C CB  . TYR C 1 384 ? -35.869 0.095   71.003  1.00 57.41  ? 384 TYR C CB  1 
ATOM   9868  C CG  . TYR C 1 384 ? -36.912 0.970   71.643  1.00 58.36  ? 384 TYR C CG  1 
ATOM   9869  C CD1 . TYR C 1 384 ? -37.948 0.417   72.381  1.00 57.00  ? 384 TYR C CD1 1 
ATOM   9870  C CD2 . TYR C 1 384 ? -36.791 2.344   71.613  1.00 54.85  ? 384 TYR C CD2 1 
ATOM   9871  C CE1 . TYR C 1 384 ? -38.868 1.214   73.038  1.00 62.23  ? 384 TYR C CE1 1 
ATOM   9872  C CE2 . TYR C 1 384 ? -37.712 3.155   72.250  1.00 61.16  ? 384 TYR C CE2 1 
ATOM   9873  C CZ  . TYR C 1 384 ? -38.755 2.591   72.966  1.00 63.90  ? 384 TYR C CZ  1 
ATOM   9874  O OH  . TYR C 1 384 ? -39.665 3.403   73.611  1.00 67.62  ? 384 TYR C OH  1 
ATOM   9875  N N   . GLY C 1 385 ? -32.748 -1.617  71.731  1.00 41.12  ? 385 GLY C N   1 
ATOM   9876  C CA  . GLY C 1 385 ? -31.907 -2.762  71.399  1.00 47.47  ? 385 GLY C CA  1 
ATOM   9877  C C   . GLY C 1 385 ? -31.129 -2.603  70.093  1.00 42.48  ? 385 GLY C C   1 
ATOM   9878  O O   . GLY C 1 385 ? -30.427 -3.513  69.683  1.00 45.23  ? 385 GLY C O   1 
ATOM   9879  N N   . VAL C 1 386 ? -31.250 -1.450  69.430  1.00 39.41  ? 386 VAL C N   1 
ATOM   9880  C CA  . VAL C 1 386 ? -30.426 -1.199  68.267  1.00 37.60  ? 386 VAL C CA  1 
ATOM   9881  C C   . VAL C 1 386 ? -29.113 -0.652  68.806  1.00 40.11  ? 386 VAL C C   1 
ATOM   9882  O O   . VAL C 1 386 ? -28.942 0.566   68.922  1.00 38.24  ? 386 VAL C O   1 
ATOM   9883  C CB  . VAL C 1 386 ? -31.113 -0.267  67.253  1.00 38.25  ? 386 VAL C CB  1 
ATOM   9884  C CG1 . VAL C 1 386 ? -30.335 -0.151  65.935  1.00 39.40  ? 386 VAL C CG1 1 
ATOM   9885  C CG2 . VAL C 1 386 ? -32.536 -0.730  66.978  1.00 40.54  ? 386 VAL C CG2 1 
ATOM   9886  N N   . VAL C 1 387 ? -28.208 -1.592  69.149  1.00 40.84  ? 387 VAL C N   1 
ATOM   9887  C CA  . VAL C 1 387 ? -26.963 -1.296  69.852  1.00 40.42  ? 387 VAL C CA  1 
ATOM   9888  C C   . VAL C 1 387 ? -25.774 -1.267  68.890  1.00 42.22  ? 387 VAL C C   1 
ATOM   9889  O O   . VAL C 1 387 ? -24.628 -1.024  69.299  1.00 44.73  ? 387 VAL C O   1 
ATOM   9890  C CB  . VAL C 1 387 ? -26.737 -2.335  70.963  1.00 43.25  ? 387 VAL C CB  1 
ATOM   9891  C CG1 . VAL C 1 387 ? -27.901 -2.342  71.939  1.00 45.19  ? 387 VAL C CG1 1 
ATOM   9892  C CG2 . VAL C 1 387 ? -26.473 -3.746  70.416  1.00 39.89  ? 387 VAL C CG2 1 
ATOM   9893  N N   . GLU C 1 388 ? -26.064 -1.492  67.599  1.00 43.52  ? 388 GLU C N   1 
ATOM   9894  C CA  . GLU C 1 388 ? -25.066 -1.559  66.539  1.00 38.51  ? 388 GLU C CA  1 
ATOM   9895  C C   . GLU C 1 388 ? -24.944 -0.159  65.947  1.00 36.92  ? 388 GLU C C   1 
ATOM   9896  O O   . GLU C 1 388 ? -25.688 0.236   65.048  1.00 38.76  ? 388 GLU C O   1 
ATOM   9897  C CB  . GLU C 1 388 ? -25.487 -2.654  65.550  1.00 41.62  ? 388 GLU C CB  1 
ATOM   9898  C CG  . GLU C 1 388 ? -25.789 -4.012  66.216  1.00 42.27  ? 388 GLU C CG  1 
ATOM   9899  C CD  . GLU C 1 388 ? -27.169 -4.335  66.803  1.00 45.98  ? 388 GLU C CD  1 
ATOM   9900  O OE1 . GLU C 1 388 ? -28.054 -3.432  66.880  1.00 43.26  ? 388 GLU C OE1 1 
ATOM   9901  O OE2 . GLU C 1 388 ? -27.380 -5.516  67.190  1.00 50.25  ? 388 GLU C OE2 1 
ATOM   9902  N N   . TYR C 1 389 ? -23.995 0.596   66.502  1.00 39.32  ? 389 TYR C N   1 
ATOM   9903  C CA  . TYR C 1 389 ? -23.766 2.008   66.212  1.00 44.10  ? 389 TYR C CA  1 
ATOM   9904  C C   . TYR C 1 389 ? -23.690 2.309   64.715  1.00 47.78  ? 389 TYR C C   1 
ATOM   9905  O O   . TYR C 1 389 ? -24.255 3.322   64.267  1.00 44.27  ? 389 TYR C O   1 
ATOM   9906  C CB  . TYR C 1 389 ? -22.443 2.474   66.838  1.00 51.03  ? 389 TYR C CB  1 
ATOM   9907  C CG  . TYR C 1 389 ? -22.328 2.278   68.335  1.00 52.99  ? 389 TYR C CG  1 
ATOM   9908  C CD1 . TYR C 1 389 ? -23.010 3.107   69.209  1.00 49.38  ? 389 TYR C CD1 1 
ATOM   9909  C CD2 . TYR C 1 389 ? -21.533 1.270   68.883  1.00 55.39  ? 389 TYR C CD2 1 
ATOM   9910  C CE1 . TYR C 1 389 ? -22.898 2.957   70.581  1.00 53.49  ? 389 TYR C CE1 1 
ATOM   9911  C CE2 . TYR C 1 389 ? -21.426 1.095   70.255  1.00 53.51  ? 389 TYR C CE2 1 
ATOM   9912  C CZ  . TYR C 1 389 ? -22.099 1.953   71.109  1.00 53.54  ? 389 TYR C CZ  1 
ATOM   9913  O OH  . TYR C 1 389 ? -22.019 1.825   72.479  1.00 48.22  ? 389 TYR C OH  1 
ATOM   9914  N N   . ASP C 1 390 ? -22.963 1.456   63.959  1.00 46.09  ? 390 ASP C N   1 
ATOM   9915  C CA  . ASP C 1 390 ? -22.615 1.758   62.570  1.00 46.51  ? 390 ASP C CA  1 
ATOM   9916  C C   . ASP C 1 390 ? -23.866 1.824   61.698  1.00 40.83  ? 390 ASP C C   1 
ATOM   9917  O O   . ASP C 1 390 ? -23.897 2.576   60.716  1.00 44.70  ? 390 ASP C O   1 
ATOM   9918  C CB  . ASP C 1 390 ? -21.609 0.749   62.011  1.00 55.00  ? 390 ASP C CB  1 
ATOM   9919  C CG  . ASP C 1 390 ? -20.195 0.902   62.566  1.00 62.07  ? 390 ASP C CG  1 
ATOM   9920  O OD1 . ASP C 1 390 ? -19.950 1.869   63.287  1.00 74.12  ? 390 ASP C OD1 1 
ATOM   9921  O OD2 . ASP C 1 390 ? -19.335 0.050   62.271  1.00 67.46  ? 390 ASP C OD2 1 
ATOM   9922  N N   . PHE C 1 391 ? -24.885 1.064   62.120  1.00 34.79  ? 391 PHE C N   1 
ATOM   9923  C CA  . PHE C 1 391 ? -26.164 0.973   61.450  1.00 33.74  ? 391 PHE C CA  1 
ATOM   9924  C C   . PHE C 1 391 ? -27.029 2.236   61.606  1.00 34.86  ? 391 PHE C C   1 
ATOM   9925  O O   . PHE C 1 391 ? -27.989 2.439   60.845  1.00 34.27  ? 391 PHE C O   1 
ATOM   9926  C CB  . PHE C 1 391 ? -26.919 -0.227  62.003  1.00 33.39  ? 391 PHE C CB  1 
ATOM   9927  C CG  . PHE C 1 391 ? -28.128 -0.579  61.175  1.00 34.82  ? 391 PHE C CG  1 
ATOM   9928  C CD1 . PHE C 1 391 ? -27.974 -1.175  59.933  1.00 33.05  ? 391 PHE C CD1 1 
ATOM   9929  C CD2 . PHE C 1 391 ? -29.407 -0.263  61.621  1.00 33.26  ? 391 PHE C CD2 1 
ATOM   9930  C CE1 . PHE C 1 391 ? -29.073 -1.455  59.149  1.00 32.90  ? 391 PHE C CE1 1 
ATOM   9931  C CE2 . PHE C 1 391 ? -30.513 -0.568  60.850  1.00 32.96  ? 391 PHE C CE2 1 
ATOM   9932  C CZ  . PHE C 1 391 ? -30.339 -1.170  59.621  1.00 36.95  ? 391 PHE C CZ  1 
ATOM   9933  N N   . TYR C 1 392 ? -26.718 3.126   62.556  1.00 35.32  ? 392 TYR C N   1 
ATOM   9934  C CA  . TYR C 1 392 ? -27.567 4.295   62.735  1.00 38.64  ? 392 TYR C CA  1 
ATOM   9935  C C   . TYR C 1 392 ? -27.622 5.119   61.446  1.00 40.86  ? 392 TYR C C   1 
ATOM   9936  O O   . TYR C 1 392 ? -28.634 5.721   61.112  1.00 43.81  ? 392 TYR C O   1 
ATOM   9937  C CB  . TYR C 1 392 ? -27.106 5.127   63.935  1.00 40.33  ? 392 TYR C CB  1 
ATOM   9938  C CG  . TYR C 1 392 ? -27.291 4.497   65.298  1.00 38.94  ? 392 TYR C CG  1 
ATOM   9939  C CD1 . TYR C 1 392 ? -28.076 3.378   65.482  1.00 42.99  ? 392 TYR C CD1 1 
ATOM   9940  C CD2 . TYR C 1 392 ? -26.628 4.993   66.403  1.00 37.66  ? 392 TYR C CD2 1 
ATOM   9941  C CE1 . TYR C 1 392 ? -28.228 2.789   66.732  1.00 45.89  ? 392 TYR C CE1 1 
ATOM   9942  C CE2 . TYR C 1 392 ? -26.761 4.413   67.658  1.00 43.32  ? 392 TYR C CE2 1 
ATOM   9943  C CZ  . TYR C 1 392 ? -27.584 3.317   67.837  1.00 43.29  ? 392 TYR C CZ  1 
ATOM   9944  O OH  . TYR C 1 392 ? -27.687 2.684   69.062  1.00 35.82  ? 392 TYR C OH  1 
ATOM   9945  N N   . THR C 1 393 ? -26.513 5.138   60.716  1.00 39.80  ? 393 THR C N   1 
ATOM   9946  C CA  . THR C 1 393 ? -26.392 5.930   59.511  1.00 37.84  ? 393 THR C CA  1 
ATOM   9947  C C   . THR C 1 393 ? -27.271 5.347   58.411  1.00 34.31  ? 393 THR C C   1 
ATOM   9948  O O   . THR C 1 393 ? -27.834 6.081   57.606  1.00 35.24  ? 393 THR C O   1 
ATOM   9949  C CB  . THR C 1 393 ? -24.907 6.044   59.140  1.00 43.76  ? 393 THR C CB  1 
ATOM   9950  O OG1 . THR C 1 393 ? -24.283 6.423   60.379  1.00 49.83  ? 393 THR C OG1 1 
ATOM   9951  C CG2 . THR C 1 393 ? -24.596 7.028   58.024  1.00 40.52  ? 393 THR C CG2 1 
ATOM   9952  N N   . VAL C 1 394 ? -27.404 4.025   58.381  1.00 32.66  ? 394 VAL C N   1 
ATOM   9953  C CA  . VAL C 1 394 ? -28.355 3.425   57.466  1.00 34.82  ? 394 VAL C CA  1 
ATOM   9954  C C   . VAL C 1 394 ? -29.781 3.922   57.726  1.00 35.15  ? 394 VAL C C   1 
ATOM   9955  O O   . VAL C 1 394 ? -30.541 4.058   56.763  1.00 36.98  ? 394 VAL C O   1 
ATOM   9956  C CB  . VAL C 1 394 ? -28.308 1.896   57.502  1.00 34.84  ? 394 VAL C CB  1 
ATOM   9957  C CG1 . VAL C 1 394 ? -29.357 1.296   56.583  1.00 34.20  ? 394 VAL C CG1 1 
ATOM   9958  C CG2 . VAL C 1 394 ? -26.932 1.375   57.134  1.00 39.62  ? 394 VAL C CG2 1 
ATOM   9959  N N   . LEU C 1 395 ? -30.168 4.141   59.002  1.00 31.23  ? 395 LEU C N   1 
ATOM   9960  C CA  . LEU C 1 395 ? -31.521 4.588   59.320  1.00 26.51  ? 395 LEU C CA  1 
ATOM   9961  C C   . LEU C 1 395 ? -31.738 5.997   58.794  1.00 28.78  ? 395 LEU C C   1 
ATOM   9962  O O   . LEU C 1 395 ? -32.779 6.329   58.211  1.00 28.88  ? 395 LEU C O   1 
ATOM   9963  C CB  . LEU C 1 395 ? -31.725 4.612   60.827  1.00 26.18  ? 395 LEU C CB  1 
ATOM   9964  C CG  . LEU C 1 395 ? -31.679 3.280   61.541  1.00 26.26  ? 395 LEU C CG  1 
ATOM   9965  C CD1 . LEU C 1 395 ? -31.630 3.485   63.038  1.00 28.50  ? 395 LEU C CD1 1 
ATOM   9966  C CD2 . LEU C 1 395 ? -32.893 2.468   61.181  1.00 27.75  ? 395 LEU C CD2 1 
ATOM   9967  N N   . PHE C 1 396 ? -30.740 6.836   59.076  1.00 31.44  ? 396 PHE C N   1 
ATOM   9968  C CA  . PHE C 1 396 ? -30.673 8.186   58.553  1.00 30.73  ? 396 PHE C CA  1 
ATOM   9969  C C   . PHE C 1 396 ? -30.934 8.125   57.048  1.00 30.18  ? 396 PHE C C   1 
ATOM   9970  O O   . PHE C 1 396 ? -31.841 8.819   56.577  1.00 35.07  ? 396 PHE C O   1 
ATOM   9971  C CB  . PHE C 1 396 ? -29.328 8.791   58.972  1.00 33.02  ? 396 PHE C CB  1 
ATOM   9972  C CG  . PHE C 1 396 ? -29.183 10.285  58.792  1.00 38.03  ? 396 PHE C CG  1 
ATOM   9973  C CD1 . PHE C 1 396 ? -29.953 11.004  57.878  1.00 43.35  ? 396 PHE C CD1 1 
ATOM   9974  C CD2 . PHE C 1 396 ? -28.258 10.985  59.538  1.00 41.56  ? 396 PHE C CD2 1 
ATOM   9975  C CE1 . PHE C 1 396 ? -29.804 12.371  57.717  1.00 44.44  ? 396 PHE C CE1 1 
ATOM   9976  C CE2 . PHE C 1 396 ? -28.125 12.358  59.392  1.00 44.09  ? 396 PHE C CE2 1 
ATOM   9977  C CZ  . PHE C 1 396 ? -28.891 13.050  58.480  1.00 43.81  ? 396 PHE C CZ  1 
ATOM   9978  N N   . GLY C 1 397 ? -30.172 7.269   56.332  1.00 26.88  ? 397 GLY C N   1 
ATOM   9979  C CA  . GLY C 1 397 ? -30.249 7.144   54.882  1.00 26.63  ? 397 GLY C CA  1 
ATOM   9980  C C   . GLY C 1 397 ? -31.625 6.728   54.348  1.00 30.47  ? 397 GLY C C   1 
ATOM   9981  O O   . GLY C 1 397 ? -32.028 7.168   53.267  1.00 34.66  ? 397 GLY C O   1 
ATOM   9982  N N   . ILE C 1 398 ? -32.349 5.868   55.080  1.00 32.05  ? 398 ILE C N   1 
ATOM   9983  C CA  . ILE C 1 398 ? -33.710 5.507   54.696  1.00 35.43  ? 398 ILE C CA  1 
ATOM   9984  C C   . ILE C 1 398 ? -34.612 6.751   54.823  1.00 41.65  ? 398 ILE C C   1 
ATOM   9985  O O   . ILE C 1 398 ? -35.372 7.086   53.907  1.00 42.39  ? 398 ILE C O   1 
ATOM   9986  C CB  . ILE C 1 398 ? -34.197 4.323   55.555  1.00 35.61  ? 398 ILE C CB  1 
ATOM   9987  C CG1 . ILE C 1 398 ? -33.361 3.060   55.326  1.00 35.07  ? 398 ILE C CG1 1 
ATOM   9988  C CG2 . ILE C 1 398 ? -35.667 4.044   55.324  1.00 35.98  ? 398 ILE C CG2 1 
ATOM   9989  C CD1 . ILE C 1 398 ? -33.509 2.044   56.422  1.00 34.43  ? 398 ILE C CD1 1 
ATOM   9990  N N   . GLY C 1 399 ? -34.496 7.473   55.951  1.00 33.70  ? 399 GLY C N   1 
ATOM   9991  C CA  . GLY C 1 399 ? -35.324 8.644   56.199  1.00 34.14  ? 399 GLY C CA  1 
ATOM   9992  C C   . GLY C 1 399 ? -35.092 9.756   55.185  1.00 35.05  ? 399 GLY C C   1 
ATOM   9993  O O   . GLY C 1 399 ? -36.036 10.233  54.576  1.00 33.84  ? 399 GLY C O   1 
ATOM   9994  N N   . ARG C 1 400 ? -33.821 10.142  55.004  1.00 36.60  ? 400 ARG C N   1 
ATOM   9995  C CA  . ARG C 1 400 ? -33.400 11.193  54.083  1.00 33.67  ? 400 ARG C CA  1 
ATOM   9996  C C   . ARG C 1 400 ? -33.842 10.937  52.640  1.00 31.43  ? 400 ARG C C   1 
ATOM   9997  O O   . ARG C 1 400 ? -33.966 11.865  51.843  1.00 32.58  ? 400 ARG C O   1 
ATOM   9998  C CB  . ARG C 1 400 ? -31.878 11.329  54.202  1.00 36.07  ? 400 ARG C CB  1 
ATOM   9999  C CG  . ARG C 1 400 ? -31.258 12.457  53.389  1.00 36.89  ? 400 ARG C CG  1 
ATOM   10000 C CD  . ARG C 1 400 ? -32.050 13.771  53.414  1.00 34.84  ? 400 ARG C CD  1 
ATOM   10001 N NE  . ARG C 1 400 ? -32.318 14.273  54.759  1.00 34.62  ? 400 ARG C NE  1 
ATOM   10002 C CZ  . ARG C 1 400 ? -31.422 14.935  55.508  1.00 34.46  ? 400 ARG C CZ  1 
ATOM   10003 N NH1 . ARG C 1 400 ? -30.256 15.300  54.976  1.00 28.42  ? 400 ARG C NH1 1 
ATOM   10004 N NH2 . ARG C 1 400 ? -31.726 15.240  56.765  1.00 28.85  ? 400 ARG C NH2 1 
ATOM   10005 N N   . ALA C 1 401 ? -34.131 9.693   52.275  1.00 32.80  ? 401 ALA C N   1 
ATOM   10006 C CA  . ALA C 1 401 ? -34.531 9.425   50.899  1.00 32.88  ? 401 ALA C CA  1 
ATOM   10007 C C   . ALA C 1 401 ? -35.880 10.059  50.583  1.00 30.65  ? 401 ALA C C   1 
ATOM   10008 O O   . ALA C 1 401 ? -36.138 10.374  49.428  1.00 25.34  ? 401 ALA C O   1 
ATOM   10009 C CB  . ALA C 1 401 ? -34.568 7.942   50.641  1.00 36.50  ? 401 ALA C CB  1 
ATOM   10010 N N   . LEU C 1 402 ? -36.745 10.211  51.597  1.00 30.04  ? 402 LEU C N   1 
ATOM   10011 C CA  . LEU C 1 402 ? -38.085 10.763  51.401  1.00 31.58  ? 402 LEU C CA  1 
ATOM   10012 C C   . LEU C 1 402 ? -37.966 12.139  50.769  1.00 30.24  ? 402 LEU C C   1 
ATOM   10013 O O   . LEU C 1 402 ? -38.588 12.423  49.746  1.00 32.33  ? 402 LEU C O   1 
ATOM   10014 C CB  . LEU C 1 402 ? -38.820 10.882  52.744  1.00 32.11  ? 402 LEU C CB  1 
ATOM   10015 C CG  . LEU C 1 402 ? -39.173 9.566   53.448  1.00 37.36  ? 402 LEU C CG  1 
ATOM   10016 C CD1 . LEU C 1 402 ? -39.519 9.797   54.918  1.00 43.23  ? 402 LEU C CD1 1 
ATOM   10017 C CD2 . LEU C 1 402 ? -40.332 8.846   52.771  1.00 36.11  ? 402 LEU C CD2 1 
ATOM   10018 N N   . GLY C 1 403 ? -37.125 12.977  51.385  1.00 29.17  ? 403 GLY C N   1 
ATOM   10019 C CA  . GLY C 1 403 ? -36.935 14.328  50.914  1.00 30.50  ? 403 GLY C CA  1 
ATOM   10020 C C   . GLY C 1 403 ? -36.152 14.363  49.613  1.00 31.11  ? 403 GLY C C   1 
ATOM   10021 O O   . GLY C 1 403 ? -36.516 15.104  48.704  1.00 32.96  ? 403 GLY C O   1 
ATOM   10022 N N   . VAL C 1 404 ? -35.081 13.564  49.548  1.00 33.11  ? 404 VAL C N   1 
ATOM   10023 C CA  . VAL C 1 404 ? -34.149 13.654  48.434  1.00 32.90  ? 404 VAL C CA  1 
ATOM   10024 C C   . VAL C 1 404 ? -34.826 13.188  47.151  1.00 30.86  ? 404 VAL C C   1 
ATOM   10025 O O   . VAL C 1 404 ? -34.680 13.858  46.141  1.00 25.73  ? 404 VAL C O   1 
ATOM   10026 C CB  . VAL C 1 404 ? -32.860 12.858  48.687  1.00 33.11  ? 404 VAL C CB  1 
ATOM   10027 C CG1 . VAL C 1 404 ? -32.033 12.738  47.421  1.00 35.37  ? 404 VAL C CG1 1 
ATOM   10028 C CG2 . VAL C 1 404 ? -32.028 13.493  49.782  1.00 36.78  ? 404 VAL C CG2 1 
ATOM   10029 N N   . LEU C 1 405 ? -35.547 12.055  47.210  1.00 30.58  ? 405 LEU C N   1 
ATOM   10030 C CA  . LEU C 1 405 ? -36.176 11.472  46.031  1.00 36.14  ? 405 LEU C CA  1 
ATOM   10031 C C   . LEU C 1 405 ? -37.284 12.393  45.517  1.00 40.21  ? 405 LEU C C   1 
ATOM   10032 O O   . LEU C 1 405 ? -37.391 12.582  44.303  1.00 45.97  ? 405 LEU C O   1 
ATOM   10033 C CB  . LEU C 1 405 ? -36.685 10.056  46.342  1.00 36.48  ? 405 LEU C CB  1 
ATOM   10034 C CG  . LEU C 1 405 ? -35.610 9.006   46.657  1.00 39.19  ? 405 LEU C CG  1 
ATOM   10035 C CD1 . LEU C 1 405 ? -36.213 7.644   46.944  1.00 42.19  ? 405 LEU C CD1 1 
ATOM   10036 C CD2 . LEU C 1 405 ? -34.612 8.868   45.514  1.00 41.69  ? 405 LEU C CD2 1 
ATOM   10037 N N   . ALA C 1 406 ? -38.061 12.993  46.435  1.00 43.98  ? 406 ALA C N   1 
ATOM   10038 C CA  . ALA C 1 406 ? -39.040 14.025  46.090  1.00 46.61  ? 406 ALA C CA  1 
ATOM   10039 C C   . ALA C 1 406 ? -38.359 15.216  45.413  1.00 45.24  ? 406 ALA C C   1 
ATOM   10040 O O   . ALA C 1 406 ? -38.811 15.680  44.369  1.00 47.62  ? 406 ALA C O   1 
ATOM   10041 C CB  . ALA C 1 406 ? -39.808 14.458  47.318  1.00 44.57  ? 406 ALA C CB  1 
ATOM   10042 N N   . ASN C 1 407 ? -37.242 15.666  45.978  1.00 38.00  ? 407 ASN C N   1 
ATOM   10043 C CA  . ASN C 1 407 ? -36.497 16.751  45.369  1.00 41.11  ? 407 ASN C CA  1 
ATOM   10044 C C   . ASN C 1 407 ? -36.013 16.365  43.965  1.00 34.33  ? 407 ASN C C   1 
ATOM   10045 O O   . ASN C 1 407 ? -36.041 17.192  43.090  1.00 39.19  ? 407 ASN C O   1 
ATOM   10046 C CB  . ASN C 1 407 ? -35.357 17.231  46.274  1.00 46.97  ? 407 ASN C CB  1 
ATOM   10047 C CG  . ASN C 1 407 ? -34.855 18.615  45.914  1.00 54.32  ? 407 ASN C CG  1 
ATOM   10048 O OD1 . ASN C 1 407 ? -33.653 18.820  45.701  1.00 63.43  ? 407 ASN C OD1 1 
ATOM   10049 N ND2 . ASN C 1 407 ? -35.778 19.569  45.833  1.00 53.62  ? 407 ASN C ND2 1 
ATOM   10050 N N   . LEU C 1 408 ? -35.615 15.122  43.702  1.00 34.14  ? 408 LEU C N   1 
ATOM   10051 C CA  . LEU C 1 408 ? -35.112 14.747  42.377  1.00 34.51  ? 408 LEU C CA  1 
ATOM   10052 C C   . LEU C 1 408 ? -36.221 14.780  41.328  1.00 33.34  ? 408 LEU C C   1 
ATOM   10053 O O   . LEU C 1 408 ? -35.967 15.034  40.150  1.00 29.57  ? 408 LEU C O   1 
ATOM   10054 C CB  . LEU C 1 408 ? -34.507 13.342  42.385  1.00 33.40  ? 408 LEU C CB  1 
ATOM   10055 C CG  . LEU C 1 408 ? -33.312 13.119  43.320  1.00 37.95  ? 408 LEU C CG  1 
ATOM   10056 C CD1 . LEU C 1 408 ? -32.640 11.803  42.998  1.00 37.72  ? 408 LEU C CD1 1 
ATOM   10057 C CD2 . LEU C 1 408 ? -32.320 14.291  43.292  1.00 37.78  ? 408 LEU C CD2 1 
ATOM   10058 N N   . VAL C 1 409 ? -37.442 14.455  41.748  1.00 36.41  ? 409 VAL C N   1 
ATOM   10059 C CA  . VAL C 1 409 ? -38.570 14.485  40.827  1.00 43.21  ? 409 VAL C CA  1 
ATOM   10060 C C   . VAL C 1 409 ? -38.821 15.926  40.372  1.00 39.58  ? 409 VAL C C   1 
ATOM   10061 O O   . VAL C 1 409 ? -38.950 16.196  39.189  1.00 41.50  ? 409 VAL C O   1 
ATOM   10062 C CB  . VAL C 1 409 ? -39.842 13.880  41.444  1.00 41.60  ? 409 VAL C CB  1 
ATOM   10063 C CG1 . VAL C 1 409 ? -40.995 13.994  40.469  1.00 43.97  ? 409 VAL C CG1 1 
ATOM   10064 C CG2 . VAL C 1 409 ? -39.661 12.428  41.844  1.00 40.24  ? 409 VAL C CG2 1 
ATOM   10065 N N   . TRP C 1 410 ? -38.847 16.845  41.332  1.00 39.34  ? 410 TRP C N   1 
ATOM   10066 C CA  . TRP C 1 410 ? -39.022 18.261  41.058  1.00 39.16  ? 410 TRP C CA  1 
ATOM   10067 C C   . TRP C 1 410 ? -37.890 18.844  40.206  1.00 36.86  ? 410 TRP C C   1 
ATOM   10068 O O   . TRP C 1 410 ? -38.143 19.562  39.260  1.00 38.18  ? 410 TRP C O   1 
ATOM   10069 C CB  . TRP C 1 410 ? -39.258 19.000  42.377  1.00 39.12  ? 410 TRP C CB  1 
ATOM   10070 C CG  . TRP C 1 410 ? -40.693 18.874  42.798  1.00 41.50  ? 410 TRP C CG  1 
ATOM   10071 C CD1 . TRP C 1 410 ? -41.216 17.990  43.693  1.00 39.35  ? 410 TRP C CD1 1 
ATOM   10072 C CD2 . TRP C 1 410 ? -41.815 19.599  42.248  1.00 43.93  ? 410 TRP C CD2 1 
ATOM   10073 N NE1 . TRP C 1 410 ? -42.578 18.109  43.745  1.00 43.03  ? 410 TRP C NE1 1 
ATOM   10074 C CE2 . TRP C 1 410 ? -42.974 19.103  42.885  1.00 43.33  ? 410 TRP C CE2 1 
ATOM   10075 C CE3 . TRP C 1 410 ? -41.943 20.619  41.291  1.00 43.91  ? 410 TRP C CE3 1 
ATOM   10076 C CZ2 . TRP C 1 410 ? -44.243 19.620  42.625  1.00 40.50  ? 410 TRP C CZ2 1 
ATOM   10077 C CZ3 . TRP C 1 410 ? -43.197 21.131  41.034  1.00 45.65  ? 410 TRP C CZ3 1 
ATOM   10078 C CH2 . TRP C 1 410 ? -44.327 20.633  41.696  1.00 44.89  ? 410 TRP C CH2 1 
ATOM   10079 N N   . ASP C 1 411 ? -36.651 18.472  40.460  1.00 38.44  ? 411 ASP C N   1 
ATOM   10080 C CA  . ASP C 1 411 ? -35.530 18.957  39.666  1.00 42.51  ? 411 ASP C CA  1 
ATOM   10081 C C   . ASP C 1 411 ? -35.747 18.650  38.184  1.00 35.74  ? 411 ASP C C   1 
ATOM   10082 O O   . ASP C 1 411 ? -35.419 19.463  37.316  1.00 34.24  ? 411 ASP C O   1 
ATOM   10083 C CB  . ASP C 1 411 ? -34.199 18.349  40.141  1.00 51.78  ? 411 ASP C CB  1 
ATOM   10084 C CG  . ASP C 1 411 ? -33.700 18.806  41.512  1.00 60.02  ? 411 ASP C CG  1 
ATOM   10085 O OD1 . ASP C 1 411 ? -34.189 19.872  41.999  1.00 74.81  ? 411 ASP C OD1 1 
ATOM   10086 O OD2 . ASP C 1 411 ? -32.828 18.086  42.107  1.00 70.76  ? 411 ASP C OD2 1 
ATOM   10087 N N   . ARG C 1 412 ? -36.295 17.464  37.901  1.00 35.51  ? 412 ARG C N   1 
ATOM   10088 C CA  . ARG C 1 412 ? -36.547 17.048  36.532  1.00 39.17  ? 412 ARG C CA  1 
ATOM   10089 C C   . ARG C 1 412 ? -37.815 17.702  36.001  1.00 39.22  ? 412 ARG C C   1 
ATOM   10090 O O   . ARG C 1 412 ? -37.881 18.066  34.823  1.00 35.97  ? 412 ARG C O   1 
ATOM   10091 C CB  . ARG C 1 412 ? -36.670 15.529  36.438  1.00 44.70  ? 412 ARG C CB  1 
ATOM   10092 C CG  . ARG C 1 412 ? -35.353 14.787  36.639  1.00 48.26  ? 412 ARG C CG  1 
ATOM   10093 C CD  . ARG C 1 412 ? -34.352 14.960  35.503  1.00 52.07  ? 412 ARG C CD  1 
ATOM   10094 N NE  . ARG C 1 412 ? -33.664 16.254  35.476  1.00 57.40  ? 412 ARG C NE  1 
ATOM   10095 C CZ  . ARG C 1 412 ? -32.949 16.747  36.484  1.00 56.11  ? 412 ARG C CZ  1 
ATOM   10096 N NH1 . ARG C 1 412 ? -32.490 17.985  36.413  1.00 50.19  ? 412 ARG C NH1 1 
ATOM   10097 N NH2 . ARG C 1 412 ? -32.739 16.011  37.570  1.00 55.18  ? 412 ARG C NH2 1 
ATOM   10098 N N   . ALA C 1 413 ? -38.803 17.840  36.898  1.00 38.44  ? 413 ALA C N   1 
ATOM   10099 C CA  . ALA C 1 413 ? -40.065 18.491  36.595  1.00 37.25  ? 413 ALA C CA  1 
ATOM   10100 C C   . ALA C 1 413 ? -39.782 19.898  36.062  1.00 40.03  ? 413 ALA C C   1 
ATOM   10101 O O   . ALA C 1 413 ? -40.242 20.255  34.976  1.00 36.25  ? 413 ALA C O   1 
ATOM   10102 C CB  . ALA C 1 413 ? -40.931 18.509  37.830  1.00 31.76  ? 413 ALA C CB  1 
ATOM   10103 N N   . LEU C 1 414 ? -38.945 20.657  36.792  1.00 40.42  ? 414 LEU C N   1 
ATOM   10104 C CA  . LEU C 1 414 ? -38.678 22.056  36.482  1.00 38.96  ? 414 LEU C CA  1 
ATOM   10105 C C   . LEU C 1 414 ? -37.518 22.219  35.497  1.00 40.23  ? 414 LEU C C   1 
ATOM   10106 O O   . LEU C 1 414 ? -37.128 23.357  35.206  1.00 41.24  ? 414 LEU C O   1 
ATOM   10107 C CB  . LEU C 1 414 ? -38.389 22.815  37.783  1.00 36.72  ? 414 LEU C CB  1 
ATOM   10108 C CG  . LEU C 1 414 ? -39.479 22.709  38.854  1.00 36.98  ? 414 LEU C CG  1 
ATOM   10109 C CD1 . LEU C 1 414 ? -39.094 23.506  40.079  1.00 39.98  ? 414 LEU C CD1 1 
ATOM   10110 C CD2 . LEU C 1 414 ? -40.825 23.160  38.340  1.00 41.17  ? 414 LEU C CD2 1 
ATOM   10111 N N   . GLY C 1 415 ? -36.915 21.097  35.072  1.00 40.57  ? 415 GLY C N   1 
ATOM   10112 C CA  . GLY C 1 415 ? -35.884 21.108  34.048  1.00 37.06  ? 415 GLY C CA  1 
ATOM   10113 C C   . GLY C 1 415 ? -34.584 21.763  34.498  1.00 38.03  ? 415 GLY C C   1 
ATOM   10114 O O   . GLY C 1 415 ? -33.858 22.269  33.648  1.00 39.66  ? 415 GLY C O   1 
ATOM   10115 N N   . TYR C 1 416 ? -34.249 21.701  35.804  1.00 42.36  ? 416 TYR C N   1 
ATOM   10116 C CA  . TYR C 1 416 ? -33.035 22.359  36.300  1.00 45.40  ? 416 TYR C CA  1 
ATOM   10117 C C   . TYR C 1 416 ? -31.784 21.817  35.599  1.00 42.98  ? 416 TYR C C   1 
ATOM   10118 O O   . TYR C 1 416 ? -31.689 20.615  35.308  1.00 43.43  ? 416 TYR C O   1 
ATOM   10119 C CB  . TYR C 1 416 ? -32.866 22.201  37.809  1.00 42.08  ? 416 TYR C CB  1 
ATOM   10120 C CG  . TYR C 1 416 ? -33.827 22.983  38.669  1.00 46.46  ? 416 TYR C CG  1 
ATOM   10121 C CD1 . TYR C 1 416 ? -34.497 24.120  38.234  1.00 46.82  ? 416 TYR C CD1 1 
ATOM   10122 C CD2 . TYR C 1 416 ? -34.070 22.560  39.960  1.00 48.28  ? 416 TYR C CD2 1 
ATOM   10123 C CE1 . TYR C 1 416 ? -35.361 24.808  39.078  1.00 46.31  ? 416 TYR C CE1 1 
ATOM   10124 C CE2 . TYR C 1 416 ? -34.942 23.217  40.807  1.00 44.78  ? 416 TYR C CE2 1 
ATOM   10125 C CZ  . TYR C 1 416 ? -35.587 24.355  40.376  1.00 47.07  ? 416 TYR C CZ  1 
ATOM   10126 O OH  . TYR C 1 416 ? -36.451 24.926  41.314  1.00 45.88  ? 416 TYR C OH  1 
ATOM   10127 N N   . ALA C 1 417 ? -30.819 22.712  35.337  1.00 38.31  ? 417 ALA C N   1 
ATOM   10128 C CA  . ALA C 1 417 ? -29.710 22.367  34.460  1.00 35.76  ? 417 ALA C CA  1 
ATOM   10129 C C   . ALA C 1 417 ? -28.593 21.737  35.276  1.00 41.09  ? 417 ALA C C   1 
ATOM   10130 O O   . ALA C 1 417 ? -28.603 21.758  36.511  1.00 44.69  ? 417 ALA C O   1 
ATOM   10131 C CB  . ALA C 1 417 ? -29.199 23.545  33.690  1.00 33.73  ? 417 ALA C CB  1 
ATOM   10132 N N   . ILE C 1 418 ? -27.643 21.158  34.538  1.00 40.58  ? 418 ILE C N   1 
ATOM   10133 C CA  . ILE C 1 418 ? -26.470 20.524  35.107  1.00 38.98  ? 418 ILE C CA  1 
ATOM   10134 C C   . ILE C 1 418 ? -25.726 21.531  35.992  1.00 42.60  ? 418 ILE C C   1 
ATOM   10135 O O   . ILE C 1 418 ? -25.629 22.715  35.663  1.00 43.39  ? 418 ILE C O   1 
ATOM   10136 C CB  . ILE C 1 418 ? -25.633 19.950  33.941  1.00 40.96  ? 418 ILE C CB  1 
ATOM   10137 C CG1 . ILE C 1 418 ? -24.477 19.072  34.431  1.00 39.22  ? 418 ILE C CG1 1 
ATOM   10138 C CG2 . ILE C 1 418 ? -25.177 21.041  32.977  1.00 38.89  ? 418 ILE C CG2 1 
ATOM   10139 C CD1 . ILE C 1 418 ? -23.729 18.381  33.324  1.00 39.73  ? 418 ILE C CD1 1 
ATOM   10140 N N   . GLU C 1 419 ? -25.259 21.053  37.157  1.00 48.37  ? 419 GLU C N   1 
ATOM   10141 C CA  . GLU C 1 419 ? -24.509 21.863  38.106  1.00 46.49  ? 419 GLU C CA  1 
ATOM   10142 C C   . GLU C 1 419 ? -23.047 21.885  37.669  1.00 41.13  ? 419 GLU C C   1 
ATOM   10143 O O   . GLU C 1 419 ? -22.386 20.867  37.690  1.00 43.45  ? 419 GLU C O   1 
ATOM   10144 C CB  . GLU C 1 419 ? -24.745 21.325  39.521  1.00 48.80  ? 419 GLU C CB  1 
ATOM   10145 C CG  . GLU C 1 419 ? -24.053 22.097  40.647  1.00 52.69  ? 419 GLU C CG  1 
ATOM   10146 C CD  . GLU C 1 419 ? -24.601 21.824  42.057  1.00 59.52  ? 419 GLU C CD  1 
ATOM   10147 O OE1 . GLU C 1 419 ? -25.837 21.963  42.270  1.00 80.88  ? 419 GLU C OE1 1 
ATOM   10148 O OE2 . GLU C 1 419 ? -23.807 21.476  42.955  1.00 59.16  ? 419 GLU C OE2 1 
ATOM   10149 N N   . ARG C 1 420 ? -22.573 23.058  37.249  1.00 43.30  ? 420 ARG C N   1 
ATOM   10150 C CA  . ARG C 1 420 ? -21.232 23.243  36.707  1.00 48.12  ? 420 ARG C CA  1 
ATOM   10151 C C   . ARG C 1 420 ? -20.761 24.630  37.145  1.00 46.56  ? 420 ARG C C   1 
ATOM   10152 O O   . ARG C 1 420 ? -20.838 25.584  36.374  1.00 42.40  ? 420 ARG C O   1 
ATOM   10153 C CB  . ARG C 1 420 ? -21.242 23.083  35.174  1.00 50.97  ? 420 ARG C CB  1 
ATOM   10154 C CG  . ARG C 1 420 ? -19.923 22.669  34.534  1.00 54.80  ? 420 ARG C CG  1 
ATOM   10155 C CD  . ARG C 1 420 ? -18.682 23.424  35.009  1.00 62.16  ? 420 ARG C CD  1 
ATOM   10156 N NE  . ARG C 1 420 ? -17.448 23.016  34.324  1.00 60.14  ? 420 ARG C NE  1 
ATOM   10157 C CZ  . ARG C 1 420 ? -16.201 23.196  34.784  1.00 56.40  ? 420 ARG C CZ  1 
ATOM   10158 N NH1 . ARG C 1 420 ? -15.962 23.962  35.846  1.00 41.63  ? 420 ARG C NH1 1 
ATOM   10159 N NH2 . ARG C 1 420 ? -15.194 22.603  34.156  1.00 53.52  ? 420 ARG C NH2 1 
ATOM   10160 N N   . PRO C 1 421 ? -20.344 24.813  38.419  1.00 46.47  ? 421 PRO C N   1 
ATOM   10161 C CA  . PRO C 1 421 ? -19.724 26.059  38.866  1.00 43.34  ? 421 PRO C CA  1 
ATOM   10162 C C   . PRO C 1 421 ? -18.306 26.157  38.323  1.00 43.48  ? 421 PRO C C   1 
ATOM   10163 O O   . PRO C 1 421 ? -17.830 25.222  37.678  1.00 44.90  ? 421 PRO C O   1 
ATOM   10164 C CB  . PRO C 1 421 ? -19.723 25.964  40.393  1.00 41.42  ? 421 PRO C CB  1 
ATOM   10165 C CG  . PRO C 1 421 ? -19.696 24.495  40.663  1.00 47.10  ? 421 PRO C CG  1 
ATOM   10166 C CD  . PRO C 1 421 ? -20.450 23.844  39.515  1.00 49.26  ? 421 PRO C CD  1 
ATOM   10167 N N   . LYS C 1 422 ? -17.668 27.304  38.581  1.00 44.88  ? 422 LYS C N   1 
ATOM   10168 C CA  . LYS C 1 422 ? -16.350 27.608  38.061  1.00 41.46  ? 422 LYS C CA  1 
ATOM   10169 C C   . LYS C 1 422 ? -15.314 27.472  39.177  1.00 44.48  ? 422 LYS C C   1 
ATOM   10170 O O   . LYS C 1 422 ? -15.560 27.835  40.322  1.00 39.97  ? 422 LYS C O   1 
ATOM   10171 C CB  . LYS C 1 422 ? -16.352 29.000  37.435  1.00 39.05  ? 422 LYS C CB  1 
ATOM   10172 C CG  . LYS C 1 422 ? -15.135 29.305  36.568  1.00 44.65  ? 422 LYS C CG  1 
ATOM   10173 C CD  . LYS C 1 422 ? -15.064 28.493  35.269  1.00 46.98  ? 422 LYS C CD  1 
ATOM   10174 C CE  . LYS C 1 422 ? -13.936 28.914  34.340  1.00 49.13  ? 422 LYS C CE  1 
ATOM   10175 N NZ  . LYS C 1 422 ? -12.619 28.345  34.717  1.00 50.04  ? 422 LYS C NZ  1 
ATOM   10176 N N   . SER C 1 423 ? -14.158 26.901  38.817  1.00 49.13  ? 423 SER C N   1 
ATOM   10177 C CA  . SER C 1 423 ? -13.036 26.731  39.726  1.00 51.96  ? 423 SER C CA  1 
ATOM   10178 C C   . SER C 1 423 ? -12.001 27.828  39.493  1.00 51.69  ? 423 SER C C   1 
ATOM   10179 O O   . SER C 1 423 ? -11.878 28.369  38.392  1.00 44.03  ? 423 SER C O   1 
ATOM   10180 C CB  . SER C 1 423 ? -12.381 25.378  39.551  1.00 51.96  ? 423 SER C CB  1 
ATOM   10181 O OG  . SER C 1 423 ? -13.353 24.356  39.536  1.00 53.57  ? 423 SER C OG  1 
ATOM   10182 N N   . VAL C 1 424 ? -11.218 28.086  40.543  1.00 49.91  ? 424 VAL C N   1 
ATOM   10183 C CA  . VAL C 1 424 ? -10.143 29.056  40.488  1.00 51.62  ? 424 VAL C CA  1 
ATOM   10184 C C   . VAL C 1 424 ? -8.968  28.494  41.278  1.00 54.01  ? 424 VAL C C   1 
ATOM   10185 O O   . VAL C 1 424 ? -9.141  27.643  42.145  1.00 52.72  ? 424 VAL C O   1 
ATOM   10186 C CB  . VAL C 1 424 ? -10.601 30.424  41.030  1.00 49.55  ? 424 VAL C CB  1 
ATOM   10187 C CG1 . VAL C 1 424 ? -11.838 30.926  40.278  1.00 54.67  ? 424 VAL C CG1 1 
ATOM   10188 C CG2 . VAL C 1 424 ? -10.848 30.405  42.535  1.00 42.74  ? 424 VAL C CG2 1 
ATOM   10189 N N   . THR C 1 425 ? -7.765  28.988  40.976  1.00 54.32  ? 425 THR C N   1 
ATOM   10190 C CA  . THR C 1 425 ? -6.562  28.522  41.640  1.00 47.51  ? 425 THR C CA  1 
ATOM   10191 C C   . THR C 1 425 ? -6.304  29.427  42.829  1.00 45.88  ? 425 THR C C   1 
ATOM   10192 O O   . THR C 1 425 ? -6.969  30.440  42.995  1.00 42.05  ? 425 THR C O   1 
ATOM   10193 C CB  . THR C 1 425 ? -5.374  28.494  40.673  1.00 47.36  ? 425 THR C CB  1 
ATOM   10194 O OG1 . THR C 1 425 ? -5.003  29.840  40.377  1.00 50.26  ? 425 THR C OG1 1 
ATOM   10195 C CG2 . THR C 1 425 ? -5.706  27.784  39.380  1.00 48.28  ? 425 THR C CG2 1 
ATOM   10196 N N   . THR C 1 426 ? -5.349  29.017  43.655  1.00 47.89  ? 426 THR C N   1 
ATOM   10197 C CA  . THR C 1 426 ? -4.809  29.841  44.713  1.00 48.18  ? 426 THR C CA  1 
ATOM   10198 C C   . THR C 1 426 ? -4.051  31.022  44.109  1.00 47.88  ? 426 THR C C   1 
ATOM   10199 O O   . THR C 1 426 ? -4.160  32.124  44.637  1.00 40.71  ? 426 THR C O   1 
ATOM   10200 C CB  . THR C 1 426 ? -3.883  28.995  45.594  1.00 58.94  ? 426 THR C CB  1 
ATOM   10201 O OG1 . THR C 1 426 ? -4.578  27.779  45.895  1.00 57.25  ? 426 THR C OG1 1 
ATOM   10202 C CG2 . THR C 1 426 ? -3.427  29.735  46.839  1.00 59.44  ? 426 THR C CG2 1 
ATOM   10203 N N   . ASP C 1 427 ? -3.311  30.786  43.004  1.00 44.12  ? 427 ASP C N   1 
ATOM   10204 C CA  . ASP C 1 427 ? -2.645  31.847  42.257  1.00 53.01  ? 427 ASP C CA  1 
ATOM   10205 C C   . ASP C 1 427 ? -3.618  32.967  41.872  1.00 55.71  ? 427 ASP C C   1 
ATOM   10206 O O   . ASP C 1 427 ? -3.306  34.151  42.024  1.00 63.75  ? 427 ASP C O   1 
ATOM   10207 C CB  . ASP C 1 427 ? -1.942  31.318  41.001  1.00 57.99  ? 427 ASP C CB  1 
ATOM   10208 C CG  . ASP C 1 427 ? -0.588  30.669  41.282  1.00 68.91  ? 427 ASP C CG  1 
ATOM   10209 O OD1 . ASP C 1 427 ? -0.322  30.343  42.469  1.00 72.85  ? 427 ASP C OD1 1 
ATOM   10210 O OD2 . ASP C 1 427 ? 0.215   30.515  40.322  1.00 61.55  ? 427 ASP C OD2 1 
ATOM   10211 N N   . MET C 1 428 ? -4.782  32.582  41.350  1.00 50.49  ? 428 MET C N   1 
ATOM   10212 C CA  . MET C 1 428 ? -5.817  33.514  40.949  1.00 48.26  ? 428 MET C CA  1 
ATOM   10213 C C   . MET C 1 428 ? -6.411  34.225  42.165  1.00 47.69  ? 428 MET C C   1 
ATOM   10214 O O   . MET C 1 428 ? -6.623  35.425  42.102  1.00 55.10  ? 428 MET C O   1 
ATOM   10215 C CB  . MET C 1 428 ? -6.922  32.778  40.187  1.00 51.56  ? 428 MET C CB  1 
ATOM   10216 C CG  . MET C 1 428 ? -6.548  32.507  38.746  1.00 53.17  ? 428 MET C CG  1 
ATOM   10217 S SD  . MET C 1 428 ? -7.634  31.288  37.938  1.00 56.61  ? 428 MET C SD  1 
ATOM   10218 C CE  . MET C 1 428 ? -9.139  32.251  37.746  1.00 60.80  ? 428 MET C CE  1 
ATOM   10219 N N   . LEU C 1 429 ? -6.676  33.520  43.273  1.00 47.59  ? 429 LEU C N   1 
ATOM   10220 C CA  . LEU C 1 429 ? -7.176  34.170  44.484  1.00 53.38  ? 429 LEU C CA  1 
ATOM   10221 C C   . LEU C 1 429 ? -6.156  35.167  45.042  1.00 57.81  ? 429 LEU C C   1 
ATOM   10222 O O   . LEU C 1 429 ? -6.519  36.092  45.764  1.00 61.08  ? 429 LEU C O   1 
ATOM   10223 C CB  . LEU C 1 429 ? -7.454  33.122  45.566  1.00 52.43  ? 429 LEU C CB  1 
ATOM   10224 C CG  . LEU C 1 429 ? -8.671  32.226  45.353  1.00 55.88  ? 429 LEU C CG  1 
ATOM   10225 C CD1 . LEU C 1 429 ? -8.774  31.218  46.495  1.00 56.54  ? 429 LEU C CD1 1 
ATOM   10226 C CD2 . LEU C 1 429 ? -9.941  33.046  45.224  1.00 53.33  ? 429 LEU C CD2 1 
ATOM   10227 N N   . GLU C 1 430 ? -4.876  34.898  44.774  1.00 54.36  ? 430 GLU C N   1 
ATOM   10228 C CA  . GLU C 1 430 ? -3.778  35.693  45.282  1.00 58.05  ? 430 GLU C CA  1 
ATOM   10229 C C   . GLU C 1 430 ? -3.632  36.959  44.442  1.00 62.04  ? 430 GLU C C   1 
ATOM   10230 O O   . GLU C 1 430 ? -3.361  38.018  44.999  1.00 57.58  ? 430 GLU C O   1 
ATOM   10231 C CB  . GLU C 1 430 ? -2.498  34.851  45.337  1.00 56.58  ? 430 GLU C CB  1 
ATOM   10232 C CG  . GLU C 1 430 ? -2.410  34.049  46.628  1.00 54.37  ? 430 GLU C CG  1 
ATOM   10233 C CD  . GLU C 1 430 ? -1.166  33.200  46.837  1.00 58.01  ? 430 GLU C CD  1 
ATOM   10234 O OE1 . GLU C 1 430 ? -0.475  32.869  45.830  1.00 50.79  ? 430 GLU C OE1 1 
ATOM   10235 O OE2 . GLU C 1 430 ? -0.866  32.903  48.034  1.00 60.52  ? 430 GLU C OE2 1 
ATOM   10236 N N   . LYS C 1 431 ? -3.830  36.855  43.119  1.00 67.15  ? 431 LYS C N   1 
ATOM   10237 C CA  . LYS C 1 431 ? -3.925  38.031  42.264  1.00 72.96  ? 431 LYS C CA  1 
ATOM   10238 C C   . LYS C 1 431 ? -5.049  38.961  42.777  1.00 76.03  ? 431 LYS C C   1 
ATOM   10239 O O   . LYS C 1 431 ? -4.797  40.133  43.038  1.00 72.92  ? 431 LYS C O   1 
ATOM   10240 C CB  . LYS C 1 431 ? -4.106  37.606  40.797  1.00 73.08  ? 431 LYS C CB  1 
ATOM   10241 C CG  . LYS C 1 431 ? -3.321  38.376  39.738  1.00 85.65  ? 431 LYS C CG  1 
ATOM   10242 C CD  . LYS C 1 431 ? -3.104  39.876  40.007  1.00 116.78 ? 431 LYS C CD  1 
ATOM   10243 C CE  . LYS C 1 431 ? -4.362  40.729  40.046  1.00 131.61 ? 431 LYS C CE  1 
ATOM   10244 N NZ  . LYS C 1 431 ? -4.592  41.486  38.793  1.00 129.51 ? 431 LYS C NZ  1 
ATOM   10245 N N   . TRP C 1 432 ? -6.277  38.449  42.972  1.00 76.11  ? 432 TRP C N   1 
ATOM   10246 C CA  . TRP C 1 432 ? -7.416  39.258  43.412  1.00 78.60  ? 432 TRP C CA  1 
ATOM   10247 C C   . TRP C 1 432 ? -7.236  39.827  44.824  1.00 73.05  ? 432 TRP C C   1 
ATOM   10248 O O   . TRP C 1 432 ? -7.900  40.786  45.193  1.00 74.93  ? 432 TRP C O   1 
ATOM   10249 C CB  . TRP C 1 432 ? -8.751  38.491  43.334  1.00 85.32  ? 432 TRP C CB  1 
ATOM   10250 C CG  . TRP C 1 432 ? -9.283  38.324  41.943  1.00 98.81  ? 432 TRP C CG  1 
ATOM   10251 C CD1 . TRP C 1 432 ? -9.343  39.269  40.955  1.00 110.59 ? 432 TRP C CD1 1 
ATOM   10252 C CD2 . TRP C 1 432 ? -9.831  37.117  41.377  1.00 112.96 ? 432 TRP C CD2 1 
ATOM   10253 N NE1 . TRP C 1 432 ? -9.861  38.726  39.812  1.00 126.35 ? 432 TRP C NE1 1 
ATOM   10254 C CE2 . TRP C 1 432 ? -10.173 37.408  40.038  1.00 125.56 ? 432 TRP C CE2 1 
ATOM   10255 C CE3 . TRP C 1 432 ? -10.041 35.814  41.857  1.00 107.80 ? 432 TRP C CE3 1 
ATOM   10256 C CZ2 . TRP C 1 432 ? -10.732 36.449  39.189  1.00 109.89 ? 432 TRP C CZ2 1 
ATOM   10257 C CZ3 . TRP C 1 432 ? -10.601 34.874  41.020  1.00 95.39  ? 432 TRP C CZ3 1 
ATOM   10258 C CH2 . TRP C 1 432 ? -10.937 35.190  39.705  1.00 94.22  ? 432 TRP C CH2 1 
ATOM   10259 N N   . ALA C 1 433 ? -6.393  39.229  45.659  1.00 70.91  ? 433 ALA C N   1 
ATOM   10260 C CA  . ALA C 1 433 ? -6.131  39.803  46.969  1.00 75.50  ? 433 ALA C CA  1 
ATOM   10261 C C   . ALA C 1 433 ? -5.072  40.903  46.868  1.00 78.34  ? 433 ALA C C   1 
ATOM   10262 O O   . ALA C 1 433 ? -4.902  41.653  47.825  1.00 64.65  ? 433 ALA C O   1 
ATOM   10263 C CB  . ALA C 1 433 ? -5.700  38.719  47.931  1.00 84.55  ? 433 ALA C CB  1 
ATOM   10264 N N   . GLY C 1 434 ? -4.328  40.923  45.756  1.00 82.04  ? 434 GLY C N   1 
ATOM   10265 C CA  . GLY C 1 434 ? -3.232  41.892  45.567  1.00 75.25  ? 434 GLY C CA  1 
ATOM   10266 C C   . GLY C 1 434 ? -1.941  41.426  46.215  1.00 85.29  ? 434 GLY C C   1 
ATOM   10267 O O   . GLY C 1 434 ? -1.622  41.954  47.288  1.00 101.57 ? 434 GLY C O   1 
ATOM   10268 N N   . ILE C 1 435 ? -1.195  40.507  45.587  1.00 87.13  ? 435 ILE C N   1 
ATOM   10269 C CA  . ILE C 1 435 ? 0.003   39.945  46.215  1.00 84.73  ? 435 ILE C CA  1 
ATOM   10270 C C   . ILE C 1 435 ? 1.166   39.889  45.203  1.00 81.01  ? 435 ILE C C   1 
ATOM   10271 O O   . ILE C 1 435 ? 1.225   38.921  44.424  1.00 69.89  ? 435 ILE C O   1 
ATOM   10272 C CB  . ILE C 1 435 ? -0.317  38.581  46.879  1.00 71.75  ? 435 ILE C CB  1 
ATOM   10273 C CG1 . ILE C 1 435 ? -1.311  38.767  48.036  1.00 66.07  ? 435 ILE C CG1 1 
ATOM   10274 C CG2 . ILE C 1 435 ? 0.949   37.851  47.318  1.00 68.80  ? 435 ILE C CG2 1 
ATOM   10275 C CD1 . ILE C 1 435 ? -1.552  37.546  48.907  1.00 61.08  ? 435 ILE C CD1 1 
HETATM 10276 O O1  . OAA D 2 .   ? -42.884 -28.352 11.812  1.00 48.93  ? 501 OAA A O1  1 
HETATM 10277 O O2  . OAA D 2 .   ? -44.888 -28.995 12.608  1.00 57.22  ? 501 OAA A O2  1 
HETATM 10278 O O4  . OAA D 2 .   ? -45.867 -25.894 15.092  1.00 76.67  ? 501 OAA A O4  1 
HETATM 10279 O O5  . OAA D 2 .   ? -45.214 -27.220 16.694  1.00 65.66  ? 501 OAA A O5  1 
HETATM 10280 O O3  . OAA D 2 .   ? -43.645 -28.183 15.289  1.00 65.94  ? 501 OAA A O3  1 
HETATM 10281 C C1  . OAA D 2 .   ? -43.936 -28.165 12.509  1.00 63.33  ? 501 OAA A C1  1 
HETATM 10282 C C2  . OAA D 2 .   ? -44.037 -26.886 13.342  1.00 62.46  ? 501 OAA A C2  1 
HETATM 10283 C C3  . OAA D 2 .   ? -44.274 -27.267 14.781  1.00 66.16  ? 501 OAA A C3  1 
HETATM 10284 C C4  . OAA D 2 .   ? -45.143 -26.768 15.543  1.00 70.07  ? 501 OAA A C4  1 
HETATM 10285 O O1  . OAA E 2 .   ? -23.751 -45.830 14.207  1.00 61.80  ? 501 OAA B O1  1 
HETATM 10286 O O2  . OAA E 2 .   ? -23.750 -46.138 16.399  1.00 64.66  ? 501 OAA B O2  1 
HETATM 10287 O O4  . OAA E 2 .   ? -20.686 -46.977 17.566  1.00 70.53  ? 501 OAA B O4  1 
HETATM 10288 O O5  . OAA E 2 .   ? -21.439 -45.419 18.891  1.00 80.55  ? 501 OAA B O5  1 
HETATM 10289 O O3  . OAA E 2 .   ? -20.991 -43.794 16.814  1.00 49.79  ? 501 OAA B O3  1 
HETATM 10290 C C1  . OAA E 2 .   ? -23.168 -45.850 15.318  1.00 69.37  ? 501 OAA B C1  1 
HETATM 10291 C C2  . OAA E 2 .   ? -21.669 -45.518 15.359  1.00 66.53  ? 501 OAA B C2  1 
HETATM 10292 C C3  . OAA E 2 .   ? -21.170 -45.000 16.701  1.00 70.45  ? 501 OAA B C3  1 
HETATM 10293 C C4  . OAA E 2 .   ? -21.118 -45.824 17.752  1.00 77.28  ? 501 OAA B C4  1 
HETATM 10294 O O1  . OAA F 2 .   ? -26.087 20.692  56.686  1.00 57.67  ? 501 OAA C O1  1 
HETATM 10295 O O2  . OAA F 2 .   ? -28.227 20.256  57.095  1.00 58.45  ? 501 OAA C O2  1 
HETATM 10296 O O4  . OAA F 2 .   ? -28.471 16.963  56.655  1.00 57.50  ? 501 OAA C O4  1 
HETATM 10297 O O5  . OAA F 2 .   ? -29.558 16.749  58.441  1.00 51.91  ? 501 OAA C O5  1 
HETATM 10298 O O3  . OAA F 2 .   ? -27.648 17.775  59.776  1.00 67.09  ? 501 OAA C O3  1 
HETATM 10299 C C1  . OAA F 2 .   ? -26.990 19.975  57.181  1.00 65.46  ? 501 OAA C C1  1 
HETATM 10300 C C2  . OAA F 2 .   ? -26.552 18.694  57.915  1.00 68.07  ? 501 OAA C C2  1 
HETATM 10301 C C3  . OAA F 2 .   ? -27.626 17.813  58.551  1.00 64.73  ? 501 OAA C C3  1 
HETATM 10302 C C4  . OAA F 2 .   ? -28.576 17.156  57.858  1.00 56.64  ? 501 OAA C C4  1 
HETATM 10303 O O   . HOH G 3 .   ? -30.886 -13.807 41.316  1.00 28.71  ? 601 HOH A O   1 
HETATM 10304 O O   . HOH G 3 .   ? -30.952 -40.534 39.094  1.00 42.63  ? 602 HOH A O   1 
HETATM 10305 O O   . HOH G 3 .   ? -37.457 -33.389 12.862  1.00 29.51  ? 603 HOH A O   1 
HETATM 10306 O O   . HOH G 3 .   ? -47.759 -8.396  31.537  1.00 36.64  ? 604 HOH A O   1 
HETATM 10307 O O   . HOH G 3 .   ? -42.648 -15.970 40.178  1.00 28.75  ? 605 HOH A O   1 
HETATM 10308 O O   . HOH G 3 .   ? -57.998 -29.430 15.099  1.00 36.50  ? 606 HOH A O   1 
HETATM 10309 O O   . HOH G 3 .   ? -51.195 -23.015 7.752   1.00 46.81  ? 607 HOH A O   1 
HETATM 10310 O O   . HOH G 3 .   ? -48.621 -38.568 13.956  1.00 55.78  ? 608 HOH A O   1 
HETATM 10311 O O   . HOH G 3 .   ? -28.329 -14.961 35.918  1.00 35.21  ? 609 HOH A O   1 
HETATM 10312 O O   . HOH G 3 .   ? -25.393 -19.292 41.854  1.00 28.48  ? 610 HOH A O   1 
HETATM 10313 O O   . HOH G 3 .   ? -27.224 -30.891 38.295  1.00 35.30  ? 611 HOH A O   1 
HETATM 10314 O O   . HOH G 3 .   ? -51.800 -13.331 38.600  1.00 38.38  ? 612 HOH A O   1 
HETATM 10315 O O   . HOH G 3 .   ? -36.802 -40.018 32.108  1.00 42.96  ? 613 HOH A O   1 
HETATM 10316 O O   . HOH G 3 .   ? -44.955 -32.401 18.692  1.00 37.27  ? 614 HOH A O   1 
HETATM 10317 O O   . HOH G 3 .   ? -54.909 -34.118 3.725   1.00 43.71  ? 615 HOH A O   1 
HETATM 10318 O O   . HOH G 3 .   ? -53.505 -17.971 23.558  1.00 45.35  ? 616 HOH A O   1 
HETATM 10319 O O   . HOH G 3 .   ? -37.676 -36.963 38.108  1.00 31.49  ? 617 HOH A O   1 
HETATM 10320 O O   . HOH G 3 .   ? -21.311 -16.177 37.107  1.00 39.66  ? 618 HOH A O   1 
HETATM 10321 O O   . HOH G 3 .   ? -30.553 -52.024 33.916  1.00 38.43  ? 619 HOH A O   1 
HETATM 10322 O O   . HOH G 3 .   ? -40.302 -17.152 40.069  1.00 25.48  ? 620 HOH A O   1 
HETATM 10323 O O   . HOH G 3 .   ? -49.358 -53.114 31.150  1.00 35.38  ? 621 HOH A O   1 
HETATM 10324 O O   . HOH G 3 .   ? -45.132 -36.150 19.904  1.00 59.64  ? 622 HOH A O   1 
HETATM 10325 O O   . HOH G 3 .   ? -50.859 -16.092 22.720  1.00 48.73  ? 623 HOH A O   1 
HETATM 10326 O O   . HOH G 3 .   ? -59.022 -30.016 12.529  1.00 47.80  ? 624 HOH A O   1 
HETATM 10327 O O   . HOH G 3 .   ? -43.281 -29.254 45.141  1.00 36.91  ? 625 HOH A O   1 
HETATM 10328 O O   . HOH G 3 .   ? -66.810 -35.288 34.785  1.00 32.39  ? 626 HOH A O   1 
HETATM 10329 O O   . HOH G 3 .   ? -62.727 -40.384 26.132  1.00 45.39  ? 627 HOH A O   1 
HETATM 10330 O O   . HOH G 3 .   ? -53.429 -46.263 19.488  1.00 41.68  ? 628 HOH A O   1 
HETATM 10331 O O   . HOH G 3 .   ? -48.650 -16.239 45.255  1.00 42.71  ? 629 HOH A O   1 
HETATM 10332 O O   . HOH G 3 .   ? -29.310 -39.097 37.420  1.00 35.08  ? 630 HOH A O   1 
HETATM 10333 O O   . HOH G 3 .   ? -60.580 -19.773 21.723  1.00 36.87  ? 631 HOH A O   1 
HETATM 10334 O O   . HOH G 3 .   ? -26.875 -13.598 38.000  1.00 26.22  ? 632 HOH A O   1 
HETATM 10335 O O   . HOH G 3 .   ? -65.978 -36.519 38.394  1.00 29.52  ? 633 HOH A O   1 
HETATM 10336 O O   . HOH G 3 .   ? -59.207 -30.485 31.159  1.00 28.12  ? 634 HOH A O   1 
HETATM 10337 O O   . HOH G 3 .   ? -25.127 -12.768 35.740  1.00 33.07  ? 635 HOH A O   1 
HETATM 10338 O O   . HOH G 3 .   ? -45.551 -9.584  34.680  1.00 33.04  ? 636 HOH A O   1 
HETATM 10339 O O   . HOH G 3 .   ? -35.552 -43.297 27.287  1.00 41.13  ? 637 HOH A O   1 
HETATM 10340 O O   . HOH G 3 .   ? -42.760 -21.241 44.845  1.00 35.52  ? 638 HOH A O   1 
HETATM 10341 O O   . HOH G 3 .   ? -42.717 -24.315 14.228  1.00 39.15  ? 639 HOH A O   1 
HETATM 10342 O O   . HOH G 3 .   ? -42.966 -58.455 25.996  1.00 44.93  ? 640 HOH A O   1 
HETATM 10343 O O   . HOH G 3 .   ? -47.980 -3.870  25.785  1.00 34.08  ? 641 HOH A O   1 
HETATM 10344 O O   . HOH G 3 .   ? -48.445 -12.445 16.535  1.00 49.27  ? 642 HOH A O   1 
HETATM 10345 O O   . HOH G 3 .   ? -27.476 -38.167 40.915  1.00 45.72  ? 643 HOH A O   1 
HETATM 10346 O O   . HOH G 3 .   ? -41.820 -36.754 21.137  1.00 46.18  ? 644 HOH A O   1 
HETATM 10347 O O   . HOH G 3 .   ? -46.019 2.482   15.677  1.00 47.50  ? 645 HOH A O   1 
HETATM 10348 O O   . HOH G 3 .   ? -54.652 -50.382 21.794  1.00 48.56  ? 646 HOH A O   1 
HETATM 10349 O O   . HOH H 3 .   ? -40.711 -39.392 -8.604  1.00 52.49  ? 601 HOH B O   1 
HETATM 10350 O O   . HOH H 3 .   ? -14.018 -25.975 40.387  1.00 28.71  ? 602 HOH B O   1 
HETATM 10351 O O   . HOH H 3 .   ? -28.838 -29.766 25.801  1.00 39.55  ? 603 HOH B O   1 
HETATM 10352 O O   . HOH H 3 .   ? -27.549 -12.840 19.469  1.00 50.30  ? 604 HOH B O   1 
HETATM 10353 O O   . HOH H 3 .   ? -30.550 -12.487 9.979   1.00 45.78  ? 605 HOH B O   1 
HETATM 10354 O O   . HOH H 3 .   ? 2.160   -49.538 29.606  1.00 46.67  ? 606 HOH B O   1 
HETATM 10355 O O   . HOH H 3 .   ? -2.786  -47.952 16.865  1.00 44.32  ? 607 HOH B O   1 
HETATM 10356 O O   . HOH H 3 .   ? -15.160 -25.641 42.803  1.00 24.18  ? 608 HOH B O   1 
HETATM 10357 O O   . HOH H 3 .   ? -20.727 -20.918 41.153  1.00 33.00  ? 609 HOH B O   1 
HETATM 10358 O O   . HOH H 3 .   ? -27.557 -29.495 10.011  1.00 47.50  ? 610 HOH B O   1 
HETATM 10359 O O   . HOH H 3 .   ? -13.955 -59.865 10.914  1.00 46.14  ? 611 HOH B O   1 
HETATM 10360 O O   . HOH H 3 .   ? -23.518 -61.927 32.445  1.00 50.66  ? 612 HOH B O   1 
HETATM 10361 O O   . HOH H 3 .   ? -23.021 -22.057 15.356  1.00 46.84  ? 613 HOH B O   1 
HETATM 10362 O O   . HOH H 3 .   ? -35.750 -32.935 -10.570 1.00 52.03  ? 614 HOH B O   1 
HETATM 10363 O O   . HOH H 3 .   ? -2.116  -34.305 12.030  1.00 53.44  ? 615 HOH B O   1 
HETATM 10364 O O   . HOH H 3 .   ? -9.040  -27.699 34.765  1.00 28.68  ? 616 HOH B O   1 
HETATM 10365 O O   . HOH H 3 .   ? 2.187   -54.751 30.100  1.00 51.27  ? 617 HOH B O   1 
HETATM 10366 O O   . HOH H 3 .   ? -11.920 -35.575 43.984  1.00 36.63  ? 618 HOH B O   1 
HETATM 10367 O O   . HOH H 3 .   ? -17.606 -15.278 20.014  1.00 40.07  ? 619 HOH B O   1 
HETATM 10368 O O   . HOH H 3 .   ? -18.943 -11.976 25.371  1.00 35.24  ? 620 HOH B O   1 
HETATM 10369 O O   . HOH H 3 .   ? -27.418 -23.890 12.019  1.00 34.78  ? 621 HOH B O   1 
HETATM 10370 O O   . HOH H 3 .   ? -19.735 -27.442 43.987  1.00 20.76  ? 622 HOH B O   1 
HETATM 10371 O O   . HOH H 3 .   ? -6.769  -44.888 22.345  1.00 66.29  ? 623 HOH B O   1 
HETATM 10372 O O   . HOH H 3 .   ? -26.180 -22.754 -1.084  1.00 44.18  ? 625 HOH B O   1 
HETATM 10373 O O   . HOH H 3 .   ? 7.783   -58.614 30.336  1.00 51.54  ? 626 HOH B O   1 
HETATM 10374 O O   . HOH H 3 .   ? -2.189  -39.435 37.064  1.00 27.43  ? 627 HOH B O   1 
HETATM 10375 O O   . HOH H 3 .   ? -13.044 -51.914 27.107  1.00 60.54  ? 628 HOH B O   1 
HETATM 10376 O O   . HOH H 3 .   ? -33.144 -55.781 11.560  1.00 53.98  ? 630 HOH B O   1 
HETATM 10377 O O   . HOH H 3 .   ? -36.106 -40.960 7.113   1.00 61.22  ? 631 HOH B O   1 
HETATM 10378 O O   . HOH H 3 .   ? -20.480 -11.587 22.967  1.00 41.22  ? 632 HOH B O   1 
HETATM 10379 O O   . HOH I 3 .   ? -35.211 3.533   64.105  1.00 40.21  ? 601 HOH C O   1 
HETATM 10380 O O   . HOH I 3 .   ? -32.291 17.007  52.483  1.00 23.18  ? 602 HOH C O   1 
HETATM 10381 O O   . HOH I 3 .   ? -21.545 -10.439 53.185  1.00 38.13  ? 603 HOH C O   1 
HETATM 10382 O O   . HOH I 3 .   ? -33.405 16.091  75.539  1.00 31.81  ? 604 HOH C O   1 
HETATM 10383 O O   . HOH I 3 .   ? -23.640 -14.006 46.308  1.00 22.42  ? 605 HOH C O   1 
HETATM 10384 O O   . HOH I 3 .   ? -39.133 -1.734  52.066  1.00 41.58  ? 606 HOH C O   1 
HETATM 10385 O O   . HOH I 3 .   ? -33.881 37.969  32.452  1.00 44.33  ? 607 HOH C O   1 
HETATM 10386 O O   . HOH I 3 .   ? -21.334 -13.321 52.803  1.00 29.75  ? 608 HOH C O   1 
HETATM 10387 O O   . HOH I 3 .   ? -27.504 -1.224  34.841  1.00 40.67  ? 609 HOH C O   1 
HETATM 10388 O O   . HOH I 3 .   ? -34.470 7.506   38.335  1.00 44.10  ? 610 HOH C O   1 
HETATM 10389 O O   . HOH I 3 .   ? -28.650 6.868   34.576  1.00 33.44  ? 611 HOH C O   1 
HETATM 10390 O O   . HOH I 3 .   ? -22.211 5.180   45.953  1.00 63.13  ? 612 HOH C O   1 
HETATM 10391 O O   . HOH I 3 .   ? -16.911 -4.785  50.633  1.00 41.55  ? 613 HOH C O   1 
HETATM 10392 O O   . HOH I 3 .   ? -29.511 22.466  38.882  1.00 52.34  ? 614 HOH C O   1 
HETATM 10393 O O   . HOH I 3 .   ? -54.348 14.044  60.797  1.00 43.55  ? 615 HOH C O   1 
HETATM 10394 O O   . HOH I 3 .   ? -30.262 1.011   33.864  1.00 32.07  ? 616 HOH C O   1 
HETATM 10395 O O   . HOH I 3 .   ? -35.542 -7.362  68.993  1.00 25.90  ? 617 HOH C O   1 
HETATM 10396 O O   . HOH I 3 .   ? -27.938 25.704  41.513  1.00 41.31  ? 618 HOH C O   1 
HETATM 10397 O O   . HOH I 3 .   ? -27.515 10.292  70.171  1.00 43.75  ? 619 HOH C O   1 
HETATM 10398 O O   . HOH I 3 .   ? -36.389 20.969  43.120  1.00 42.03  ? 620 HOH C O   1 
HETATM 10399 O O   . HOH I 3 .   ? -47.273 24.941  32.983  1.00 37.46  ? 621 HOH C O   1 
HETATM 10400 O O   . HOH I 3 .   ? -41.911 -6.646  65.678  1.00 40.03  ? 622 HOH C O   1 
HETATM 10401 O O   . HOH I 3 .   ? -55.474 16.356  50.704  1.00 40.07  ? 623 HOH C O   1 
HETATM 10402 O O   . HOH I 3 .   ? -39.514 -10.440 53.060  1.00 42.59  ? 624 HOH C O   1 
HETATM 10403 O O   . HOH I 3 .   ? -38.171 27.370  40.928  1.00 49.17  ? 625 HOH C O   1 
HETATM 10404 O O   . HOH I 3 .   ? -34.012 7.387   67.369  1.00 47.79  ? 626 HOH C O   1 
HETATM 10405 O O   . HOH I 3 .   ? -49.421 9.945   57.329  1.00 27.75  ? 627 HOH C O   1 
HETATM 10406 O O   . HOH I 3 .   ? -30.222 18.616  33.885  1.00 36.82  ? 628 HOH C O   1 
HETATM 10407 O O   . HOH I 3 .   ? -32.455 -5.440  67.763  1.00 31.07  ? 629 HOH C O   1 
HETATM 10408 O O   . HOH I 3 .   ? -36.799 8.482   67.072  1.00 60.41  ? 630 HOH C O   1 
HETATM 10409 O O   . HOH I 3 .   ? -31.853 12.679  36.537  1.00 31.14  ? 631 HOH C O   1 
HETATM 10410 O O   . HOH I 3 .   ? -35.842 -9.349  57.793  1.00 30.86  ? 632 HOH C O   1 
HETATM 10411 O O   . HOH I 3 .   ? -33.880 -7.513  66.384  1.00 32.14  ? 633 HOH C O   1 
HETATM 10412 O O   . HOH I 3 .   ? -21.814 31.270  59.401  1.00 46.18  ? 634 HOH C O   1 
HETATM 10413 O O   . HOH I 3 .   ? -58.070 4.796   49.127  1.00 45.28  ? 635 HOH C O   1 
HETATM 10414 O O   . HOH I 3 .   ? -31.016 24.301  42.367  1.00 33.74  ? 636 HOH C O   1 
HETATM 10415 O O   . HOH I 3 .   ? -44.400 -5.955  68.755  1.00 39.36  ? 637 HOH C O   1 
HETATM 10416 O O   . HOH I 3 .   ? -46.478 26.482  41.730  1.00 44.27  ? 638 HOH C O   1 
HETATM 10417 O O   . HOH I 3 .   ? -48.633 -0.431  67.478  1.00 48.10  ? 639 HOH C O   1 
HETATM 10418 O O   . HOH I 3 .   ? -33.266 25.394  74.687  1.00 53.59  ? 640 HOH C O   1 
HETATM 10419 O O   . HOH I 3 .   ? -40.581 24.513  51.973  1.00 38.49  ? 641 HOH C O   1 
HETATM 10420 O O   . HOH I 3 .   ? -30.925 17.892  39.397  1.00 38.76  ? 642 HOH C O   1 
HETATM 10421 O O   . HOH I 3 .   ? -30.146 -1.968  75.471  1.00 45.73  ? 643 HOH C O   1 
# 
